Miracle-dz/UniFAR-FTUs huggingface dataset:
Predictive value of cardiopulmonary fitness parameters in the prognosis of patients with acute coronary syndrome after percutaneous coronary intervention

Objectives We aimed to determine the predictive value of cardiopulmonary exercise testing (CPX) in the prognosis of patients with acute coronary syndrome (ACS) treated with percutaneous coronary intervention (PCI). Methods We conducted a retrospective study including patients who underwent CPX within 1 year of PCI between September 2012 and October 2017. Patients were followed-up until the occurrence of a major adverse cardiac event (MACE) or administrative censoring (September 2019). A Cox regression model was used to identify significant predictors of a MACE. Model performance was evaluated in terms of discrimination (C-statistic) and calibration (calibration-in-the-large). Results In total, 184 patients were included and followed-up for a median 51 months (interquartile range: 36–67 months) and 32 events occurred. Multivariable analysis revealed that body mass index and Gensini score were significant predictors of a MACE. Four CPX-related variables were found to be predictive of a MACE: premature CPX termination, peak oxygen uptake, heart rate reserve, and ventilatory equivalent for carbon dioxide slope. The final prediction model had a C-statistic of 0.92 and calibration-in-the-large 0.58%. Conclusion CPX-related parameters may have high predictive value for poor outcomes in patients with ACS who undergo PCI, indicating a need for appropriate treatment and timely management.
Effect of transport length on in vivo oxidative status and breast meat characteristics in outdoor-reared chicken genotypes

Abstract The aim of the study was to evaluate the effect of transport length on in vivo oxidative status and breast meat characteristics in two chicken genotypes reared under free range conditions. A total of 200 male chicks, 100 from fast-growing (Ross 308) and 100 from medium-growing (Naked Neck) strain were used. Fifty-six of these, 28 for genotype, before slaughtering, were randomly allocated to 2 pre-slaughter conditions: absence (0 h) or 4 h of transport. The transport length significantly affected the in vivo oxidative status of broiler greatly reducing the α and δ-tocopherol, retinol and lutein + zeaxanthin content of plasma, and increased the oxidative stress (thiobarbituric acid reactive substances, TBARS) in both strains. Concerning meat quality, the pH (0, 2 and 24 h post-mortem) of breast muscles of chickens transported for 4 h, showed higher values, and respect to strains, Naked Neck had lower values. The pH values were negatively correlated with the lightness (2–24 h) and the shear force of meat. The transport length significantly affected the fatty acid profile of breast muscle, with a decrease in polyunsaturated fatty acids and an increase in TBARS value. Even the antioxidants content of breast was reduced by chicken transport (α-tocotrienol, α-, δ-tocopherol and lutein + zeaxanthin), especially in Naked Neck birds. In conclusion, the results indicate that transport for 4 h prior to slaughter, negatively affect the meat quality of poultry. Slow-growing chickens seem more sensible to stress transport due to the higher kinetic behaviour of these strains.
Analgesic efficacy of infiltration between the popliteal artery and capsule of the knee (iPACK) block added to local infiltration analgesia and continuous adductor canal block after total knee arthroplasty: a randomized clinical trial

Background A combination of motor-sparing analgesia with local infiltration analgesia (LIA) and continuous adductor canal block (CACB) may improve postoperative pain and functional recovery for total knee arthroplasty (TKA). We hypothesized that the addition of a novel technique for posterior knee block, known as the infiltration between the popliteal artery and capsule of the knee (iPACK) block, to LIA with CACB would reduce opioid requirements. Methods In this double-blinded randomized controlled trial, 72 patients were assigned to receive either LIA with CACB (LIA+CACB group) or iPACK block with LIA and CACB (iPACK+LIA+CACB group). The primary outcome was cumulative postoperative intravenous morphine consumption within 24 hours. The secondary outcomes included numerical rating scale pain scores, incidence of posterior knee pain, performance test results, patient satisfaction, length of stay, and adverse events. Results Morphine consumption within 24 hours postoperatively showed no significant intergroup difference (LIA+CACB; 1.31±1.85 mg vs iPACK+LIA+CACB; 0.61±1.25 mg, p=0.08). There were no clinically significant differences in the overall pain scores between the groups. The lower Timed Up and Go test scores on postoperative days 1 and 2, along with a shorter duration of hospitalization, were found in the iPACK+LIA+CACB group (p<0.05). Conclusion The addition of an iPACK block to the LIA and CACB does not reduce the postoperative opioid consumption nor improve analgesia. However, it may improve immediate functional performance and reduce the length of hospitalization after TKA. Trial registration number TCTR20180702001.
Histopathological characterization of L. donovani infection in RAG2-/-mice

A recent study demonstrated lower incidence of fever and hepatosplenomegaly in HIV-positive VL patients than HIV-negative VL patients, indicating that acquired immunity have important roles in development of hepatosplenomegaly also in human VL. To explore the roles of acquired immunity in pathology of VL, pathological characterization of L. donovani infection in RAG2 -/- mice was performed. One hundred million promastigotes were inoculated intraperitoneally to RAG2 -/- mice as well as BALB/c mice, and organs were harvested from the animals at 2, 4, 8 and 12 weeks after infection and examined for parasite burdens and pathological changes. L. donovani infection induced splenomegaly in BALB/c mice; the length of the spleen after 12 weeks of infected mice was as twice as that of naive mice. In contrast, such the enlargement was not observed in RAG2 -/- mice. Accumulations of mononuclear cells were found in the liver of infected BALB/c mice, whereas such the formations were less found in RAG2 -/- mice. These results suggest that development of hepatosplenomegaly during experimental VL is dependent on the T cell or B cell rather than the presence of parasites. Mongolian Journal of Agricultural Sciences Vol.15(2) 2015; 43-50
An Analysis of the Business Communication Skills Needed By Entry-Level Accountants

Numerous surveys have established the importance of communication skills for entrylevel accountants, but none has identified the specific communication skills needed. To help us identify what skills to emphasize in an accounting curriculum, members of the Institute of Management Accounting (IMA) and the American Institute of Certified Public Accountants (AICPA) were surveyed to determine (1) the relative importance of 32 business communication skills cited in business communication literature and (2) the level of satisfaction with college preparation in those skills. Based on mean ratings on two five-point scales, English skills (pertaining to spelling, grammar, and punctuation) were significantly more important than oral and writing skills. Nine communication skills were identified as needing emphasis in an accounting curriculum. In addition, the ratings varied significantly by respondent organization (AICPA versus IMA), office size, and business activity (assurance/tax, finance, other). Suggestions on how to use these results to improve an accounting curriculum are provided.1
The emerging psychosocial profile of the adult congenital heart disease patient

Purpose of review With advances in the diagnosis and treatment of congenital heart disease (CHD), over 90% of infants born with CHD now reach adulthood. Patients with CHD require lifelong care and are at an increased risk of psychological distress, neurocognitive deficits, social challenges, and a lower quality of life (QOL). There exists limited research on how to best to support the long-term mental healthcare needs of this unique cohort. There remains limited data on directed mental health interventions and their long-term results in adults with CHD (ACHD). Recent findings Recent findings indicate high incidences of anxiety and depression in this growing population and how key concepts such as trauma, illness identity, and resilience maybe playing a role in the lives of adult patients with CHD. Attention must be focused to theorize and conduct further research to determine the effectiveness of treatment options based upon these new findings. Summary Many individuals with CHD do not receive appropriate mental health screening and care. The authors advocate for effective psychosocial interventions to address patients’ illness identity and resilience, with the goal of an improved QOL in mind.
Association of GWAS‐susceptibility loci with ischemic stroke recurrence in a Han Chinese population

Recently, genome‐wide association studies (GWAS) have found many new susceptible genetic variants for ischemic stroke (IS) occurrence. However,the roles of GWAS‐susceptibility loci in stroke prognosis are just beginning. The present study aimed to examine whether these GWAS‐linked loci polymorphisms are associated with ischemic stroke recurrence in a Chinese population.
A natural endocast of an early Miocene odontocete and its implications in cetacean brain evolution

The natural endocast Museo di Geologia e Paleontologia of the Università degli Studi di Torino (MGPT)‐PU 13873 is described and analyzed in order to interpret its taxonomic affinities and its potential significance on our understanding of cetacean brain evolution. The endocast is from the early Miocene of Piedmont (between ca. 19 and 16 million years ago), Northwestern Italy, and shows a number of plesiomorphic characters. These include: scarcely rounded cerebral hemispheres, cerebellum exposed in dorsal view with little superimposition by the cerebral hemispheres, short temporal lobe, and long sylvian fissure. The distance between the hypophysis and the rostral pons is particularly high, as it was determined by the calculus of the hypothalamus quotient, suggesting that the development of a deep interpeduncular fossa was not as advanced as in living odontocetes. The encephalization quotient (EQ) of MGPT‐PU 13873 is ~1.81; therefore, this specimen shows an EQ in line with other fossil whales of the same geological age (early Miocene). Comparative analysis shows that there is a critical lack of data from the late Miocene and Pliocene that prevents us to fully understand the recent evolution of the EQ diversity in whales. Moreover, the past diversity of brain size and shape in mysticetes is virtually unknown. All these observations point to the need of additional efforts to uncover evolutionary patterns and processes on cetacean brain evolution.
Bioecology and management of the banana skipper (Erionota thrax).

Bananas and plantains are important food crops to several people in the world. One of the most important folivorous insect pest on these crops is the banana skipper; Erionota thrax. The larvae of these large butterflies can cause mean leaf defoliation of about 60 , leading to yield losses of about 20 . Indigenous to Southeast Asia, life stages of the pest are attacked by several parasitoids of which Ooencyrtus erionotae, Cotesia erionotae and Brachymeria spp. are the major ones. Infestation and parasitism of the pest varies with plant growth stages, leaf ages, between interior and field edges, and seasons. Significantly higher infestation and parasitism found on pre-flowered plants, younger leaves and during the rainy season. In addition, eggs and larvae are randomly distributed while pupae are clumped and parasitized eggs and pupae are clumped while that of larvae is random. Although E. thrax has never been reported on non-Musa species or weeds, other smaller Erionota species have been recorded on Asystacia intrusa, Ipomoea cairica, Mimosa pudica and Cloeme rutidesperma. _____________________________________________________________________________________________________________
Karyotypes and B chromosome of greater long-tailed hamster (Cricetulus triton)

The karyotypes of greater long tailed hamster (Cricetulus triton) from Jinan, Mt. Tai, Shandong Province, Mts. Changbai, Jilin Province and Xian, Shaanxi Province in China were observed by conventional and banding technique . The diploid chromosome number and karyotype are identical in the samples of Jinan, Mts. Changbai and Xian , i. e. , 2n=28, and the karyotype consists of 11 pairs of telocentric and 2 pairs of metacentric chromosomes, X chromosome is subtelocentric and Y metacentric. Diploid number of the sample from Mt. Tai is 28～29, one extra unpaired chromosome existed in the observed metaphases by 67 5%. It is B chromosome which is the smallest telocentric in the complement. A chromosomes of the sample were identical with that of samples from Jinan , Xian and Mts. Changbai.The G banded, C banded, and silver stained karyotypes have been observed, no difference was found among samples from four localities. The origin of B chromosome was discussed in the paper.
The relationship between prior sexual abuse and reactions to sexual harrassment: Literature review and empirical study.

This article examines whether individuals who have had prior sexual abuse experiences, including sexual harassment (SH) and child sexual abuse, are hypersensitive to potential SH-related stimuli or overreact to social sexual experiences. Some psychologists and legal scholars suggest that previous sexual abuse or exposure to violence against women produces altered perceptions of current interactions and situations in those women. The review of the extant empirical literature examining such relationships and the findings presented here in an interrelated set of 5 studies provide little general or consistent support for a relationship between prior abuse experiences and current perceptions about SH. Caution is advised in judging either the veracity of an SH complaint or the objectivity of a potential juror's reaction to such a claim on the basis of her prior sexual abuse experiences. The literature review and empirical study lend weight to the irrelevance of such inquiries in judging credibility of SH complainants.
SSR- Based Genetic Diversity Assessment in Tetraploid and Hexaploid Wheat Populations

Molecular analysis fora set of hexaploid(Triticum aestvium)and tetraploid(Triticum durum)wheat cultivars was investigated by applying 11 SSR primers set. The plant materials consisted of 45 genotypes 15 of which were Triticum aestivumand 30 ofT. durum obtained fromfour different regions Egypt, Greece, Cyprus and Italy. PCR products were separated on a 6% denaturing polyacrylamide gel electrophoresis and produced a total of 3840 DNA fragments which were used for the molecular analysis. The estimated parameters computed by POPGENE (Version 1.32) within the two population
Factors Limiting Fecundity and Germination in Small Populations of Silene regia (Caryophyllaceae), a Rare Hummingbird-pollinated Prairie Forb

-The prairie forb Silene regia is restricted to small isolated populations in the eastern part of its range. I examined factors that limit fecundity and germination in these small populations. Although S. regia flowers rarely self due to dichogamy, geitonogamous crosses demonstrated self-compatibility. Substantial fruit production required pollination by ruby-throated hummingbirds (Archilochus colubris). Exclusion of hummingbirds (but not most insects) sharply reduced fruit production and seed numbers. Resource competition within individual inflorescences limited percent fruit set in some populations in certain years. Clipping of neighboring vegetation and watering S. regia did not increase reproductive output significantly. Silene regia seedings emerged at low rates (<5%) in field experiments, but field emergence increased twoto three-fold with soil disturbance and burning. Natural recruitment of seedlings occurred only in burned sites. Of all factors examined, burning had the greatest positive effects on reproductive output. In addition, controlling for the effects of burning, reproductive output was greater for plants in larger than smaller populations. By increasing fecundity and recruitment, prescribed burning can be used to expand population sizes of Silene regia.
The role of G-protein-coupled receptors in the biological activity of γδ T lymphocytes

The data collected in this work represent the first evidence that G-protein-coupled signalling exist in γδ T cells via histamine and fMLP receptors. The bigenic amine histamine and the bacterial peptide fMLP have been demonstrated to be novel chemoattractant factors for circulating human γδ T cells, which are critical members of the immunological tumor surveillance machinery. Here, we analyzed the influence of histamine on the interaction of human γδ T cells with tumor cells such as the A2058 human melanoma cell line, the human Burkitt's non-Hodgkins lymphoma cell line Raji, the T-lymphoblastic lymphoma cell line Jurkat, and the NK cell-sensitive erythroleukaemia line K562. We found that histamine inhibits the spontaneous cytolytic activity of γδ T cells in response to these cell lines. The downregulation of γδ T cell mediated cytotoxicity involves the histamine receptor subtype 2 (H2R), the activation of Gs proteins and increased cAMP intracellular levels. On the other hand, histamine activates the common signalling pathways of chemotaxins such as Gi-protein-dependent actin reorganization, the increase of intracellular Ca2+ and the induction of migratory response in γδ T lymphocytes. Our data indicate that histamine contributes to the mechanism by which tumor cells escape immunological surveillance. The bacterial-cell-wall-derived peptide N-formyl-Met-Leu-Phe (fMLP) is a well characterized chemotactic factor for phagocytes such as neutrophils, monocytes and dendritic cells. Here, we analyzed the influence of fMLP on isolated human peripheral blood γδ T cells. We found that fMLP induces intracellular calcium transients, actin reorganization, CD11b upregulation and the migration of γδ T cells. Pretreating γδ T cells with pertussis toxin inhibited all fMLP-stimulated cell responses, implicating the involvement of Gi proteins in the induced signalling cascade. The present data suggest that, in addition to phagocytes, N-formyl peptides also regulate the trafficking and activation of γδ T cells.
A Culture Chamber for Tropical Rain Forest Plants

A typical greenhouse, although it may function as a tropical house or humid house, usually fails to meet the requirements for growing certain types of tropical plants, notably such rain forest epiphytes as filmy ferns, grammitid ferns, and lycopods. Humidity appears to be the most critical factor for these plants. Temperature and light must also be correct, but they are easier to control. The great success of workers at Kew Gardens and elsewhere in Great Britain in growing these difficult plants has been attributed largely to a climate which enhances efforts to maintain conditions of high humidity, moderate temperature, and indirect light. My research at the University of Michigan involves the study of fern gametophytes which propagate themselves vegetatively by means of gemmae. Self-propagating gametophytes are found in three primarily tropical fern families: Hymenophyllaceae, Vittariaceae, and Grammitidaceae (Farrar, 1967). The culture of these gametophytes apart from their sporophytes has not been difficult. Most of the variety of techniques commonly used for gametophyte culture are suitable (cf. Stokey, 1930; Steeves et al., 1955; Kleinschmidt, 1957; Miller and Miller, 1961), provided that spores or clean, healthy gametophytes are available as innoculating material. For my own work I prefer the method described by Basile (1964) for the culture of bryophytes. A problem arises, however, when
Biological characterization of Australian isolates of citrus tristeza virus and separation of subisolates by single aphid transmissions

Citrus tristeza virus in Australian citrus is a complex of isolates that differ in biological properties and rates of aphid transmission. Biological characterization of isolates on citrus indicators produced a range of symptoms varying in type and severity depending on the field host and geographical location. Single aphid transmissions with the vector Toxoptera citricida separated some of these subisolates based on biological indexing on three citrus indicators and the numbers of inclusion bodies produced. Inclusion numbers produced in Citrus aurantiifolia were positively related to isolate and subisolate severity in that host.
A NEW FORM OF THE SORICIDAE (INSECTIVORA) FROM THE PLEISTOCENE OF NORTH CHINA

The aim of our paper is to describe lower jaw of an insectivore from Chiachiashan near Tangshan in North China. It is kept in the collection of the Institute of Vertebrate Palaeontology and Palaeoanthropology of the Academia Sinica. It was probably collected by W. C. Pei together with other mammalian remains from the same locality but was not mentioned in his paper (W. C. Pei, 1930). We examined it and compared with some of the recently described European, Asian and North American forms of the Insectivora. The comparison led us to the conclusion that we were dealing with a representative of a new species and genus of the Soricidae.
Feeding Ecology of Gadwalls in Louisiana in Winter

Feeding ecology of gadwalls (Anas strepera) wintering in southwestern Louisiana was examined during November-March 1977-78. Gadwalls consumed 95.3% plant vegetation, 0.5% plant seeds, and 4.2% animal matter. Algae comprised one-third of the diet, and common widgeongrass (Ruppia maritima), dwarf spikerush (Eleocharis parvula), spiked watermilfoil (Myriophyllum spicatum), and baby pondweed (Potamogeton pusillus) were also important foods. Diet was similar for both sexes, and food preference was usually related to relative abundance of available foods. Wintering gadwalls consumed large amounts of vegetation to meet metabolic requirements, thus habitat management practices should ensure the production and availability of nutritious and preferred foods during October-May. J. WILDL. MANAGE. 46(1):71-79 Over 1 million waterfowl winter in southwestern Louisiana (H. A. Bateman, unpubl. reps., La. Wildl. and Fish. Comm., 1977-78). Many areas have been modified through construction of impoundments and weirs that regulate water levels and increase production of waterfowl foods (Chabreck 1976). However, thousands of hectares of habitat are lost annually due to oil and commercial development, channelization, diking, erosion, and saltwater intrusion (Duffy 1974). Concern over habitat loss and the welfare of wintering waterfowl has stimulated interest in the requirements of wintering waterfowl and how well present management meets these requirements (Fredrickson and Drobney 1979). Gadwalls comprise over one-third of the wintering duck population in southwestern Louisiana (Bateman, unpubl. reps., 197778). Gadwall numbers in managed areas have increased dramatically in the past few decades (Perry et al. 1971). Previous feeding-ecology studies of wintering gadwalls have been confined to the southeastern United States, and did not assess seasonal variation in diets (Kerwin and Webb 1972, Landers et al. 1976). I examined the feeding ecology of gadwalls to identify seasonal requirements and suggest modifications in present management practices that may better provide for dietary needs. I thank R. Crawford, T. Joanen, L. McNease, K. Paulus, D. Trauger, and W. Wrenn for help during the study. I am grateful to personnel of Sabine National Wildlife Refuge and Little Pecan Island Hunt Club, B. Richard, and hunters for providing gizzards. P. DuBowy helped with invertebrate identification, R. Carlson with proximate analysis of foods, and A. Afton, R. Blohm, R. Sayler, G. Swanson, and 2 anonymous referees with manuscript review. Financial support was provided by the U.S. Fish and Wildlife Service, University of North Dakota, and the Society of Sigma Xi.