Miracle-dz/UniFAR-FTUs huggingface dataset:
Melanoma in the blink of an eye: Pathologists’ rapid detection, classification, and localization of skin abnormalities

ABSTRACT Expert radiologists can quickly extract a basic “gist” understanding of a medical image following less than a second exposure, leading to above-chance diagnostic classification of images. It is currently unclear whether this pattern of results is applicable to pathology, another medical imaging domain demanding visual diagnostic interpretation. To further characterize the rapid interpretation medical images, this study examined eye movements and diagnostic decision-making when pathologists were briefly exposed to digital whole slide images of melanocytic skin biopsies. Twelve resident (N = 5), fellow (N = 5), and attending pathologists (N = 2) with experience interpreting dermatopathology briefly viewed 48 cases presented for 500 ms each, and we tracked their eye movements towards abnormalities, their ability to classify images as containing or not containing invasive melanoma, and their ability to localize critical image regions. Results demonstrated rapid shifts of the eyes towards critical abnormalities, high diagnostic sensitivity and specificity, and surprisingly high accuracy localizing critical diagnostic regions. Furthermore, when pathologists fixated critical regions with their eyes, they were subsequently more likely to successfully localize that region on an outline of the image. Results are discussed relative to models of medical image interpretation and innovative methods for monitoring and assessing expertise development during medical education and training.
Analysis of Visible Light Communication Link's Performance in Fire Smoke Environment

This paper mainly studies the communication performance of visible light communication link in fire smoke environment. Compared with the previous studies, this study no longer only considers a single wavelength and considers the influence of smoke and background light noise. Firstly, the variation of background light noise caused by sunlight during a day was analyzed, then signal-to-noise ratio (SNR) and bit error rate (BER) of the visible light communication link in fire smoke environment with different visibility were calculated, and finally, the variation of received power with the angle β between the LED optical axis and the communication link (from LED to receiver) was analyzed. The results show that, during a day from 07:00 to 18:30, background light noise first increases and then decreases, BER changes in the same trend and reaches the maximum at about 13:00, while SNR changes in the opposite trend and reaches the minimum at about 13:00. When visibility is 100 m, the maximum difference of SNR between 7:00 and 13:00 is about 19 dB, and the maximum difference of BER is about 5.3E-10. At 7:00, the maximum difference of SNR is about 13 dB between the visibility of 1 m and the visibility of 100 m, and the maximum difference of BER is about 1.44E − 11, and received power decreases with the increase of β. In addition, SNR increases with visibility of fire smoke environment, and BER changes in the opposite trend. Lastly, in order to enhance the performance of visible light communication in fire smoke environment, this paper gives the transmitting power scheme.
Verified Progress Tracking for Timely Dataflow

Large-scale stream processing systems often follow the dataflow paradigm, which enforces a program structure that exposes a high degree of parallelism. The Timely Dataflow distributed system supports expressive cyclic dataflows for which it offers low-latency data-and pipeline-parallel stream processing. To achieve high expressiveness and performance, Timely Dataflow uses an intricate distributed protocol for tracking the computation’s progress. We modeled the progress tracking protocol as a combination of two independent transition systems in the Isabelle/HOL proof assistant. We specified and verified the safety of the two components and of the combined protocol. To this end, we identified abstract assumptions on dataflow programs that are sufficient for safety and were not previously formalized
Statistical Analysis of Joint Type-I Generalized Hybrid Censoring Data from Burr XII Lifetime Distributions

The quality of the products coming from different lines of production requires some tests called comparative life tests. For lines having the same facility, the lifetime of the product is distributed by Burr XII, the lifetime distribution, and units are tested under type-I generalized hybrid censoring scheme. The observed censoring data are used under maximum likelihood and the Bayes method to estimate the model parameters. The theoretical results are discussed and assessed through data analysis and Monte Carlo simulation study. Finally, we reported some brief comments obtained from numerical computation.
Influence of Mn-Mg Co-doping on the Dielectric Properties of Barium Strontiun Titanate Thin Film

Undoped and Mn-Mg co-doped barium strontiun titanate (Ba0.25Sr0.75TiO3) thin films were deposited on Pt/Ti/SiO2/Si substrates by a sol-gel technique. X-ray diffraction (XRD) analysis and FE-SEM reveal that the films exhibite a pure perovskite phase structure, uniform grain sizes and crack-fee. The dielectric constant, loss, tunability and leakage current density are 200, 0.010, 38%, 1×10-5A/cm2, respectively, at a 1mol% Mn-Mg content. The improved BST thin films can be used for tunable microwave devices.
THE RELATIONSHIP BETWEEN SOCIO-DEMOGRAPHIC FACTORS AND CORRUPTION KNOWLEDGE AMONG MALAYSIAN PUBLIC SERVANTS: AN EXPLORATORY STUDY

It is significant to note a lack of studies and literature that address the idea of knowledge about corruption, particularly concerning Malaysia. Hence, this exploratory study has been designed to address several factors in this regard; (1) to develop a construct that will enable some form of measurement of corruption knowledge, and which is based on the interpretation of the Malaysian Anti-Corruption Act 2009 (MACC Act 2009), (2) to measure the level of corruption knowledge, and (3) to examine the effects of socio-demographic factors on the level of corruption knowledge. A ten-item construct intended to enable the level of corruption knowledge to be measured has been developed. 1,579 public servants participated in the resulting survey. Descriptive and statistical tests were performed using IBM-SPSS Statistics 21 software. The results indicated that Malaysian public servants exhibit deficiencies in their knowledge of corruption. The study also revealed that the amount of knowledge of corruption an individual might have was influenced by gender, age, education level, income, and tenure.
Supplementary of Self-Supervised 3D Mesh Reconstruction from Single Images

1. Network Structure The input data X = [I,M ] ∈ RH×W×4 is concatenated by the original RGB single image I ∈ RH×W×3 and its silhouette mask M ∈ RH×W×1. Our 3D mesh reconstruction model consists of 4 sub-encoders, i.e. Camera Encoder Ec, Light Encoder El, Shape Encoder Es, and Texture Encoder Et. These sub-encoders separately encode corresponding attribute feature to avoid mutual effect, as illustrated in Fig. 1. The landmark feature extractor Ef is the conventional U-Net network whose output resolution is equal to the input resolution H ×W and output channel is 128. The landmark classification network is a MLP network with three layers whose output dimension is V . 2. Limitations and Failure Cases Although our SMR can effectively reconstruct 3D mesh object on multiple category-specific datasets with only 2D silhouette annotations, there are still two main limitations to be overcome in the near future: Limitation 1: Silhouette Annotations. It still requires silhouette annotations. For the sake of simplification, we have not considered the influence of background information. For some category-specific objects, such as horse, we annotate their silhouette annotations by detectron2. Thus the incorrect annotations will influence the reconstructed results. The failure case is illustrated in Fig. 2. Limitation 2: Non-Rigid Objects. It is not fit for non-grid objects, like the humans or flowers. Since it is difficult to determine the canonical viewpoints and the topological limitations of mesh representation. To avoid these limitations, we will further predict the silhouette masks by self-supervised learning and build a fully unsupervised 3D reconstruction model for more general objects. 3. More Reconstruction Results 3D Reconstruction On ShapeNet On the Shapenet dataset, since our SMR aims to model category-specific object, we perform experiments on these 13 categories one-byone. We introduce the ground truth camera parameters so as to evaluate the reconstructed accuracy and compare with other supervised methods to demonstrate SMR’s effective5x5 Conv, 32 5x5 Conv, 64 5x5 Conv, 128
Ecology of Pairbond Stability

Humans are a pairbonding species, and this is reflected in our behaviour and our physiology (Quinlan 2008). While their form and duration varies, pairbonds exist in all human societies—and there are very few, if any, exceptions to this rule. To understand the stability of pairbonds it is useful to look at the contexts under which they are unstable, to examine the factors that increase the probability of divorce or dissolution. These factors have been well studied by scholars in sociology, psychology, anthropology, medicine, and law. Despite this, the ecological factors driving pairbond stability and divorce have received much less attention in humans as they have in studies of other pairbonding species, like birds.
Handling Extreme Class Imbalance in Technical Logbook Datasets

Technical logbooks are a challenging and under-explored text type in automated event identification. These texts are typically short and written in non-standard yet technical language, posing challenges to off-the-shelf NLP pipelines. The granularity of issue types described in these datasets additionally leads to class imbalance, making it challenging for models to accurately predict which issue each logbook entry describes. In this paper we focus on the problem of technical issue classification by considering logbook datasets from the automotive, aviation, and facilities maintenance domains. We adapt a feedback strategy from computer vision for handling extreme class imbalance, which resamples the training data based on its error in the prediction process. Our experiments show that with statistical significance this feedback strategy provides the best results for four different neural network models trained across a suite of seven different technical logbook datasets from distinct technical domains. The feedback strategy is also generic and could be applied to any learning problem with substantial class imbalances.
Reinforcement Learning for Optimizing Agent Strategies

Reinforcement learning agents are one of the best methods of general problem solving. The algorithm AlphaGo Zero (AZ) in particular achieved stateof-the-art results in solving multiple board games. However, it is suited only for solving adversary deterministic environments and finds few real-life applications, as finding complete information about real-life processes is next to impossible. In our work, we analyze how exactly does AZ function and how it can be adjusted for solving non-adversary stochastic environments, while introducing a redundancy checking technique to prune the state tree more effectively. Finally, we design a custom environment and examine how the simple DQN algorithm compares to the adjusted AZ both with and without redundancy checking, showing that the version utilizing the redundancy checking heuristic remarkably outperforms both the DQN and the unamplified AZ.
The comparison of radiofrequency and Cyanoacrylate embolization therapy in vena saphena magna ablation

Zafer Cengiz Er1, Bugra Destan2, Sedat Ozcan3 1Department of Cardiovascular Surgery, Bozok University Faculty of Medicine, Yozgat 2Department of Cardiovascular Surgery, Mehmet Akif Ersoy State Hospital, Çanakkale 3Department of Cardiovascular Surgery, Canakkale Onsekiz Mart University Faculty of Medicine, Çanakkale, Turkey The comparison of radiofrequency and Cyanoacrylate embolization theraphy The comparison of radiofrequency and Cyanoacrylate embolization therapy in vena saphena magna ablation
Ultrasonography in emergency service, evaluation of central venous catheterization

Dilay Satılmış1, Oya Güven2, Burcu Genc Yavuz3, Mehmet Özgür Erdoğan4, Şahin Çolak3 1Department of Emergency Medicine,University of Health Sciences Sultan 2 Abdülhamid Han Training and Research Hospital, Istanbul 2Department of Emergency Medicine ,Rumeli University, Kırklareli 3Department of Emergency Medicine,University of Health Sciences Haydarpaşa Numune Training and Research Hospital, Istanbul 4Department of Emergency Medicine, Bahçeşehir University, Istanbul, Turkey Ultrasonography in emergency service Ultrasonography in emergency service, evaluation of central venous catheterization
Vocabulary Learning Strategies and Cognitive Styles among Junior High School Students in Taiwan

This study investigates the use of vocabulary learning strategies (VLSs) among EFL junior high school students in Taiwan, and explores the relationship between the use of VLSs and cognitive styles. We administered a VLS questionnaire and a Hidden Figures Test (HFT) to 277 Grade 9 junior high school students. The results show that students do not often use VLSs. Moreover, cognitive style is significantly correlated with the use of the following 3 VLS categories: social strategies, memory strategies, and metacognitive strategies—but not cognitive strategies. We suggest that teachers help students understand various VLSs and their cognitive styles to improve and facilitate their learning.
Research Article: Otolith shape analysis of three mudskipper species of Persian Gulf

The variation in otolith shape of three syntopic species of mudskippers Boleophthalmus dussumieri, Periophthalmus waltoni, and Scartelaos tenuis from the tidal flats of Qeshm Island in Persian Gulf was studied based on Elliptic Fourier Analysis. Principal component analysis and Discriminant analysis could separate the specimens of every species with 100% classification success, which proves the variability of otolith among the three fish species. Cluster analysis produced two main clusters, one cluster encompasses only specimens from P. waltoni and the other contains S. tenuis and B. dussumieri. The result of the present study revealed the power of geometric morphometrics in discriminating the three mudskippers. It is also concluded that otolith traits especially its geometric morphometric could be regarded as an invaluable source of information for paleontology, phylogeny, taxonomy and ecology of fishes.
DIAGNOSING SARCOPENIA: FUNCTIONAL PERSPECTIVES AND A NEW ALGORITHM FROM ISarcoPRM

Sarcopenia is an important public health problem, characterized by age-related loss of muscle mass and muscle function. It is a precursor of physical frailty, mobility limitation, and premature death. Muscle loss is mainly due to the loss of type II muscle fibres, and progressive loss of motor neurones is thought to be the primary underlying factor. Anterior thigh muscles undergo atrophy earlier, and the loss of anterior thigh muscle function may therefore be an antecedent finding. The aim of this review is to provide an in-depth (and holistic) neuromusculoskeletal approach to sarcopenia. In addition, under the umbrella of the International Society of Physical and Rehabilitation Medicine (ISPRM), a novel diagnostic algorithm is proposed, developed with the consensus of experts in the special interest group on sarcopenia (ISarcoPRM). The advantages of this algorithm over the others are: special caution concerning disorders related to the renin-angiotensin system at the case finding stage; emphasis on anterior thigh muscle mass and function loss; incorporation of ultrasound for the first time to measure the anterior thigh muscle; and addition of a chair stand test as a power/performance test to assess anterior thigh muscle function. Refining and testing the algorithm remains a priority for future research. LAY ABSTRACT Sarcopenia is an important public health problem, characterized by age-related loss of muscle mass and muscle function. The diagnostic recommendations published to date have addressed total or appendicular muscle mass. However, under the umbrella of the International Society of Physical and Rehabilitation Medicine (ISPRM), experts in the special interest group on sarcopenia (ISarcoPRM) developed a new algorithm, based on regional measurements and functional evaluations of the anterior thigh muscle, which is the most commonly and initially affected condition in sarcopenia. Unlike other suggestions, diseases associated with the renin-angiotensin system are emphasized in this algorithm, and ultrasound has been used for measurement of anterior thigh muscle mass.
Brain activation in Highly Superior Autobiographical Memory: The role of

This is the first study to examine functional brain activation in a single case of Highly Superior Autobiographical Memory (HSAM) who shows no sign of OCD. While previous work has documented the existence of HSAM, information about brain areas involved in this exceptional form of memory for personal events relies on structural and resting state connectivity data, with mixed results so far. In this first task-based fMRI study of a normal individual with HSAM, dates were presented as cues and two phases were assessed during memory retrieval, initial access and later elaboration. Results showed that initial access was very fast, did not activate the hippocampus, and involved activation of predominantly posterior visual areas, including the precuneus. These areas typically become active during later stages of elaboration of personal memories rather than during initial access. Elaboration involved a balanced bilateral activation of most of the autobiographical network areas, rather than the more typical shifts observed in people without HSAM. Overall, the pattern of brain activations, which rests on repeated observations in a single individual, highlights a strong involvement of the precuneus and an idiosyncratic initial access to personal memory representations. Implications for the nature of personal memories in HSAM are discussed.
Sildenafil citrate in healthy and diseased hearts

Sildenafi l citrate is one of the frontline drugs used to manage erectile dysfunction (ED). Chemically, it is described as 1-[[3-(6,7-dihydro-1-methyl-7-oxo-3-propyl-1H –pyrazolo [4,3-d] pyrimidin-5-yl)-4 ethoxyphenyl] sulfonyl]-4-methylpiperazine citrate (C22H30N6O4 S). It is a highly selective inhibitor of cyclic guanine monophosphate-specifi c phosphodiesterase type-5. There had been heightened concerns following reports that sildenafi l citrate may increase the risk of cardiovascular events, particularly fatal arrhythmias, in patients with cardiovascular disease. So the cardiac electrophysiological eff ects of sildenafi l citrate have been investigated extensively in both animal and clinical studies. This article ties up the various outcomes of the investigations with a view to guiding physicians and patients that use sildenafi l citrate to manage erectile dysfunction, especially as it concerns its eff ect on their cardiovascular function in health and in disease. Sildenafi l citrate could impact negatively on ailing hearts, but on a healthy heart, there may not be any such impact, rather, it improves on heart performance as it lowers the blood pressure.
Notch1 mutation drives clonal expansion in normal esophageal epithelium but impairs tumor growth

NOTCH1 mutant clones occupy the majority of normal human esophagus by middle age, but are comparatively rare in esophageal cancers, suggesting NOTCH1 mutations may promote clonal expansion but impede carcinogenesis1–3. Here we test this hypothesis. Visualizing and sequencing NOTCH1 mutant clones in aging normal human esophagus reveals frequent biallelic mutations that block NOTCH1 signaling. In mouse esophagus, heterozygous Notch1 mutation confers a competitive advantage over wild type cells, an effect enhanced by loss of the second allele. Notch1 loss alters transcription but has minimal effects on epithelial structure and cell dynamics. In a carcinogenesis model, Notch1 mutations were less prevalent in tumors than normal epithelium. Deletion of Notch1 reduced tumor growth, an effect recapitulated by anti-NOTCH1 antibody treatment. We conclude that Notch1 mutations in normal epithelium are beneficial as wild type Notch1 promotes tumor expansion. NOTCH1 blockade may have therapeutic potential in preventing esophageal squamous cancer.
Basic tools and continuity-like properties in relator spaces

This paper provides the unification of several continuity-like properties of functions and relations in the framework of relator spaces. Motivated by Galois connections, we consider an ordered pair of relations instead of a single relation. A family R of relations on a set X to another set Y is called a relator on X to Y . All reasonable generalizations of the usual topological structures (such as proximities, closures, topologies, filters and convergences, for instance) can be derived from relators. Therefore, they should not be studied separately. From the various topological and algebraic structures (such as lower bounds, minimum and infimum, for instance) derived from relators, by using Pataki connections, we can obtain several closure and projection operations for relators. Each of them will lead to four continuity-like properties of an ordered pair of relators.
ORR_A_268517 183..188

1Department of Orthopedic Surgery, University of Manitoba, Winnipeg, MB, Canada; 2Pan Am Clinic Foundation, Winnipeg, MB, Canada Background: Semi-sterile and full preparation and draping techniques are commonly used in closed reduction percutaneous pinning (CRPP) of supracondylar fractures. Debate exists whether full preparation and draping is safer than semi-sterile technique in regards to infection risk and the utility of pre-operative antibiotics. This study is a comparison of infection rates, pre-operative antibiotic administration, cost and surgical time between techniques. Methods: A retrospective chart review of 336 pediatric patients with supracondylar fractures repaired with CRPP at our institution was completed between January 2014 and April 2018, 168 per technique. Infection rates, pre-operative antibiotic administration, preparation-to-incision time and cost in semi-sterile draping versus full preparation and draping techniques were compared. Results: Of the 336 patients, 1/168 (0.1%) in the full preparation and draping group developed an infection compared to 0/168 (0%) patients in the semi-sterile group. Preoperative antibiotics (Cefazolin) were administered to 76/168 (23%) patients in the full preparation and draping group and 0/168 (0%) in the semi-sterile group. The infection found received pre-operative antibiotics. Mean preparation-to-incision time for the semisterile group was 2.4±2.0 minutes and the full preparation and draping group was 9.9 ±4.2 minutes (p <0.001). Surgical supply cost was $80.72 [CDN] and 108.24$ [CDN], respectively, for the semi-sterile and full preparation and draping groups. Conclusion: Risk of infection using a semi-sterile draping technique was safe and comparable to a full preparation and draping technique when used in CRPP of supracondylar fractures. The administration of pre-operative antibiotics does not appear to make a difference in infection rates. Semi-sterile operative technique is cost effective and has decreased preparation-to-incision time.