Miracle-dz/UniFAR-FTUs huggingface dataset:
Can google search volume index predict the returns and trading volumes of stocks in a retail investor dominant market

Abstract This research examines whether Google search volume index (GSVI), a proxy of investor attention, can predict the excess returns and abnormal trading volumes of TPEx 50 index constituents. It also explores the motive underlying GSVI based on positive or negative shocks to stock prices. The empirical data include 48 companies from TPEx 50 index constituents and cover a period from 1 September 2016 to 31 August 2019. The empirical results present that (1) lagged GSVI negatively affects current excess returns, perhaps due to the characteristics of TPEx, in which there are a higher proportion of retail investors, smaller listed companies, and a higher information asymmetry problem. (2) Lagged GSVI can positively affect abnormal current trading volumes. (3) If GSVI is driven by positive shocks, then it can predict excess returns and abnormal trading volumes positively.
Are online learning modules the kiss of life or death for lecture attendance

Background: In their original context, lectures were once the only means of disseminating scholarly work to the eyes and ears of an elite few. The evolution of the printing press however, resulted in more affordable books that empowered self-directed learning outside of the classroom. Lecturers could subsequently set pre-reading exercises, intent on establishing an early understanding of threshold concepts, so that motivated students would explore the subject matter more deeply. More recent technological advances have now similarly re-defined the contents of the learning toolbox for the contemporary student, with the Internet providing an effective conduit for the more prolific use of interactive learning and assessment software. Purpose: Nevertheless, there is palpable concern amongst many academics that the increased use in these online resources might lead to reduced lecture attendance in institutions that still advocate the value of an on campus university experience. However, when considering the benefits of such flexible online learning conditions, the question posed in this paper is: Do the online and face-to-face (f2f) components of multi-mode delivery in a blended learning experience, mutually encourage the effective use of both in-person and digitally available resources? Design/Method: The online study habits of level-1 engineering students were observed when freely available online material became far more synchronised and pertinent to particular f2f lectures. Students were encouraged to utilise the online material in a timely manner, in preparation for quizzes that closed immediately prior to the lecture. Also, students were asked why they attended lectures and whether they thought the online resources added value to the f2f lectures. Results: It was observed that when the online material was freely available throughout the semester, and not synchronised to particular f2f lectures, the online resources were under utilised. However, once the students were encouraged to use relevant online resources in a timely manner, prior to f2f lectures, by closing the availability of a quiz beforehand, the use of the online resources increased dramatically without any adverse effect on lecture attendance. Students continued to perceive merit in the f2f lectures, as well as the online material, as long as both resources offered additional educational value. Conclusions: The online and f2f components of multi-mode delivery in a blended learning experience can mutually encourage the effective use of both in-person and digitally available resources. Poorly attended lectures may therefore not linked to the more prolific use of online resources, but most likely the result of lectures perceived as boring, unappealing, or seen as offering no additional educational experience.
Effect of Thermomechanical Treatment on Mechanical Properties and Microstructure of Titanium Alloy Ti-6AL-4V ELI for Orthopedic Applications

— Traffic accidents and osteoporosis significantly contribute to the incidence of fractures in Indonesia, increasing the need for orthopedic implant materials, such as titanium alloy Ti-6Al-4V ELI, which has good biocompatibility and availability in the market. However, its strength needs to be increased through thermomechanical treatment to maintain its durability. In this study, such treatment was applied with a combination of solution heat treatment at 950°C and a 1-hour holding time, followed by, subsequently, rapid cooling using water quenching, plastic deformation with deformation variations of 10%, 20%, and 30%, and aging treatment at a temperature of 550°C and holding time for 1.5 hours. The material surface microstructure was observed using an Olympus GX71 optical microscope; the chemical composition was measured using Electron dispersive X-ray, and; the hardness was measured using a Vickers microhardness tester. All data obtained were then analyzed to determine the effect of thermomechanical treatment on the increase and changes in the tested material’s hardness and microstructure, respectively. The results showed that thermomechanical treatment could increase the hardness of Ti-6Al-4V ELI, as expressed by the equation HVN = 135ε + 381.5, with a correlation coefficient of 0.991. Hence, it could be concluded that thermomechanical treatment can increase the hardness of Ti-6Al-4V ELI and, finally, change its microstructure, indicating an increase in the α phase. Therefore, Ti-6Al-4V ELI treated with thermomechanical treatment can be an alternate material in orthopedic implant applications
Theoretical and Experimental Results for the S414, Slotted, Natural-Laminar-Flow Airfoil

The S414, slotted, natural-laminar-flow airfoil was designed for rotorcraft applications and has been analyzed theoretically using MSES and OVERFLOW. In addition, it has been verified experimentally in the Pennsylvania State University Low-Speed, Low-Turbulence Wind Tunnel. The primary objectives of the design are high maximum lift and low profile drag, both of which have been achieved while satisfying a thickness constraint. The theoretical analyses show good agreement with the experimental results. The experimental results are compared with those of the S406 and S411 airfoils, which were designed to similar specifications, and illustrate the potential benefits of the slotted, natural-laminar-flow concept.
Psychometric Testing of the Technological Competency as Caring in Nursing Instrument – Revised (English Version Including a Practice Dimension)

Background: The middle range theory Technological Competency as Caring in Nursing (TCCN) guides nursing practices. The TCCN Instrument (TCCNI) measures perception dimension of the theory and has been revised and translated into the Japanese language (TCCNI-R). Testing the translated version of the TCCNI-R to English language with the inclusion of a practice dimension is warranted.Purpose: This study aims to determine the psychometric properties of the TCCNI-Revised English version with Practice dimension (TCCNI-RePract). Methods: A web-based cross-sectional study was conducted with data from 202 valid questionnaire copies from professional nurses in selected hospitals and nurse educators in universities. Results: The suitability for factor analysis was determined using Kaiser-Meyer-Olkin index (0.93), Bartlett's sphericity test of 3256.93, p<0.001, the anti-image correlations ranged between 0.87 and 0.96, and an average value of communalities of 0.66. In the four rotations conducted with the maximum likelihood method with a Harris-Kaiser Orthoblique rotation, four items were excluded with factor loadings less than 0.40. These results determined the final scale with 21 items and four subscales, namely: (1) Knowing the person (8 items); (2) Technological competency as Caring (6 items); (3) Technology and caring (4 items); and (4) Expression of nursing as Caring (3 items). Cronbach’s alpha coefficient for the total scale was 0.94. With two dimensions of the TCCNI-RePract, the perception dimension had significantly higher scores than the practice dimension. When comparing mean factor point among the dimensions, the perception scores were significantly higher for Factor 1 and Factor 3.Conclusion:The TCCNI-RePract is an acceptable tool that can reliably measure nurses’ perception and practice of TCCN. It is affirmed that with this tool, measuring perception and practice status of TCCN theory is possible. It is considered that the evaluation results can be used to plan in-hospital education.
Potential for the Adoption of Probabilistic Risk Assessments by End-Users and Decision-Makers

ABSTRACT In the area of risk assessment associated with ecotoxicological and plant protection products, probabilistic risk assessment (PRA) methodologies have been developed that enable quantification of variability and uncertainty. Despite the potential advantages of these new methodologies, end-user and regulatory uptake has not been, to date, extensive. A case study, utilizing the Theory of Planned Behavior, was conducted in order to identify potential determinants of end-user adoption of probabilistic risk assessments associated with the ecotoxicological impact of pesticides. Seventy potential end-users, drawn from academia, government, industry, and consultancy organizations, were included in the study. The results indicated that end-user intention to adopt PRA varied across the different end-user groups. The regulatory acceptance of PRA was contingent on social acceptance across the regulatory community regarding the reliability and utility of the outputs. Training in interpretation of outputs is therefore highly relevant to regulatory acceptance. In other end-user sectors, a positive attitude toward PRA, “hands on” experience, and perceived capability of actually performing PRA is an important determinant of end-user intention to adopt PRA. It is concluded that training programs targeted to the specific needs of different end-user sectors should be developed if end-user adoption of PRA is to be increased.
Poleward distribution of mesopelagic fishes is constrained by seasonality in light

Aim: Mesopelagic fishes have a near-global distribution in the upper 1,000 m from tropical to sub-Arctic oceans across temperature regimes. Yet, their abundance decreases poleward and viable populations seem excluded from high latitudes. Why? Location: North Atlantic between 50– 85°N, with implications for high-latitude oceans globally. Time period: Present-day. Major taxa studied: Diel vertically migrating (DVM) mesopelagic fishes. Methods: We use a mechanistic, state-dependent life-history model to characterize DVM mesopelagic fishes. This model links light-dependent encounters
Morphological Characterization of Lithognathus mormyrus (Linnaeus, 1758) Populations in the Southern Black Sea (Turkey)

Morphological characteristics such as meristic counts and body shape have long been used in stock identification. Fifty striped seabream, Lithognathus mormyrus, individuals were sampled from the south Black Sea between January 2020 and November 2020. Morphometric characteristics were given as the percentage of total length (TL%). Species identification and shape differences between sexes of striped seabream were analyzed by different statistical methods. The biggest maximum length and weight values (TL=310 mm for TW=399.73 g) were found for the southern Black Sea in this study. The mean TL of female individuals (X=205.26 mm) was found higher than male individuals (X=199.10 mm). The TL% ratio of head length was found as 24.45% for all individuals. In this study, isometric growth (t=2.009, p>0.05) was determined for all individuals and the length-weight relationship (LWR) was found as W=0.013TL3. 003 (r2=0.983). This study revealed that the morphological characteristics of L. mormyrus differ significantly between female and male individuals and the species may be a good example of sexual dimorphism.
Model-Based Efficacy and Toxicity Comparisons of Moxifloxacin for Multidrug-Resistant Tuberculosis

Abstract Background Moxifloxacin (MOX) is used as a first-choice drug to treat multidrug-resistant tuberculosis (MDR-TB); however, evidence-based dosing optimization should be strengthened by integrative analysis. The primary goal of this study was to evaluate MOX efficacy and toxicity using integrative model-based approaches in MDR-TB patients. Methods In total, 113 MDR-TB patients from 5 different clinical trials were analyzed for the development of a population pharmacokinetics (PK) model. A final population PK model was merged with a previously developed lung-lesion distribution and QT prolongation model. Monte Carlo simulation was used to calculate the probability target attainment value based on concentration. An area under the concentration-time curve (AUC)-based target was identified as the minimum inhibitory concentration (MIC) of MOX isolated from MDR-TB patients. Results The presence of human immunodeficiency virus (HIV) increased clearance by 32.7% and decreased the AUC by 27.4%, compared with HIV-negative MDR-TB patients. A daily dose of 800 mg or a 400-mg, twice-daily dose of MOX is expected to be effective in MDR-TB patients with an MIC of ≤0.25 µg/mL, regardless of PK differences resulting from the presence of HIV. The effect of MOX in HIV-positive MDR-TB patients tended to be decreased dramatically from 0.5 µg/mL, in contrast to the findings in HIV-negative patients. A regimen of twice-daily doses of 400 mg should be considered safer than an 800-mg once-daily dosing regimen, because of the narrow fluctuation of concentrations. Conclusions Our results suggest that a 400-mg, twice-daily dose of MOX is an optimal dosing regimen for MDR-TB patients because it provides superior efficacy and safety.
Tall building with steel plate shear walls subject to load reversal

This paper presents a state‐of‐the‐art review of research on thin unstiffened steel plate shear walls including recent research advances, in addition to a case study building that used them as the primary lateral‐force‐resisting system. Thin unstiffened steel plate shear walls are becoming an attractive alternative to traditional lateral‐force‐resistance systems because they exhibit desirable structural properties. A properly designed steel plate shear wall will have considerable energy dissipation capacity, ductility, initial stiffness and ultimate strength. Furthermore, the said walls are efficient in terms of cost and space due to their light weight, ease of construction and small footprint. The case study building is a 55‐story high‐rise system that took advantage of these properties. Details are presented regarding the design process and tools that were used to ensure a safe and efficient structure. Copyright © 2011 John Wiley & Sons, Ltd.
The Use of Online Synchronous Discussion Groups to Enhance Community Formation and Professional Identity Development

Synchronous online discussions are being increasingly used in higher education in order to facilitate learning and group interaction between on-campus and off-campus students. In response to calls from the engineering community to integrate humanities studies into the engineering curriculum, English and Engineering faculty at a large urban university collaborated to design an online literature discussion course for first-year engineering students. Students were assigned two works of literature that dealt with ethical and professional development issues in engineering. The online discussions took place outside class in a Multiuser Object Oriented (MOO) environment, where all discussions were logged. As researchers examined the transcripts of these discussions, the theme of community formation emerged. The transcripts were coded and then used to identify the varying levels of community formation during the course of the semester as well as the students’ development of professional identity. Results suggest that behaviors of the mentor, negotiation of group knowledge, and exclusion of late arriving members characterized communities. The results also suggest that through reading and discussion of professional issues, students may begin to view themselves as members of the engineering profession.
Pathophysiology of Non-IgE-Mediated Food Allergy

Abstract Non-IgE-mediated food allergies are a group of disorders characterized by subacute or chronic inflammatory processes in the gut. Unlike IgE mediated food allergies that may result in multi-organ system anaphylaxis, the non-IgE mediated food allergies primarily affect the gastrointestinal tract. This review outlines the clinical manifestations, epidemiology, pathophysiology, and management of non-IgE-mediated food allergies. An updated literature search of selected non-IgE-mediated food allergies was conducted for this review using PubMed database to the current year (2021). Reviewed disorders include food protein-induced enterocolitis syndrome (FPIES), food-protein enteropathy (FPE), food protein-induced allergic proctocolitis (FPIAP), and eosinophilic gastrointestinal disorders (EGIDs) such as eosinophilic esophagitis (EoE). While extensive gains have been made in understanding FPIES, FPIAP, FPE, and EoE, more information is needed on the pathophysiology of these food allergies. Similarities among them include involvement of innate immunity, T-lymphocyte processes, alteration of the intestinal lumen at the cellular level with the appearance of inflammatory cells and associated histologic changes, and specific cytokine profiles suggesting food-specific, T-cell, and immune-mediated responses. While FPIES and FPIAP typically resolve in early childhood, EGIDs typically do not. Emerging new therapies for EoE offer promise of additional treatment options. Further studies identifying the immunopathogenesis, associated biomarkers, and mechanisms of tolerance are needed to inform prevention, diagnosis and management.
Integration of Web Processing Services with Workflow-Based Scientific Applications for Solving Environmental Monitoring Problems

Nowadays, developing and applying advanced digital technologies for monitoring protected natural territories are critical problems. Collecting, digitalizing, storing, and analyzing spatiotemporal data on various aspects of the life cycle of such territories play a significant role in monitoring. Often, data processing requires the utilization of high-performance computing. To this end, the paper addresses a new approach to automation of implementing resource-intensive computational operations of web processing services in a heterogeneous distributed computing environment. To implement such an operation, we develop a workflow-based scientific application executed under the control of a multi-agent system. Agents represent heterogeneous resources of the environment and distribute the computational load among themselves. Software development is realized in the Orlando Tools framework, which we apply to creating and operating problem-oriented applications. The advantages of the proposed approach are in integrating geographic information services and high-performance computing tools, as well as in increasing computation speedup, balancing computational load, and improving the efficiency of resource use in the heterogeneous distributed computing environment. These advantages are shown in analyzing multidimensional time series.
Intraoral Digital Radiography for Adult Age Estimation: A Reliable Technique

Aims and objectives: This study aimed at estimating the age of an individual from mandibular premolars using the pulp to tooth area ratio (AR) measured from the digital intraoral radiographic images or radiovisuographic images (RVGs). Materials and methods: The study comprised of 120 patients divided into two subsets of 30 test subjects and 90 study subjects. The RVG images of mandibular premolars were acquired and the pulp to tooth area ratio was measured using the software Jenoptic ProgRess Version 2.7. Pearson’s correlation test and regression analysis was employed. Intraobserver variation was evaluated with paired t-test. Results: The AR was a significant (p-value <0.001) predictor of age with a mean absolute error (MAE) of 5.38 years using the formula, Age = 89.778-379.020 (AR). This equation when applied on the test subset revealed no statistically significant difference (p = 0. 256) between estimated and chronological ages with no gender differences. The age estimated from the RVG images were more accurate in 36 to 50 year patients. Conclusion: Considering that the acceptable error limits for forensic age estimation is being less than ±10 years, this method of age estimation provides a fairly accurate and reliable noninvasive method.
Finding genetic factors associated with cognitive abilities

The article provides an overview of the results of modern genetic studies of human cognitive abilities. Finding genetic factors, associated with cognitive abilities, will have far-reaching ramifications at all levels of understanding from DNA to brain and to behavior. Despite its complexity, cognitive ability is a reasonable candidate for molecular genetic research because it is one of the most heritable features of behavior. The first attempts to find genetic factors, associated with cognitive abilities, focused on genes, involved in brain development and function, but this direction proved to be unproductive, as it turned out that there are about 18.000 genes, and it was too difficult to detect among them those genes that are involved in cognitive processes. In addition, a considerable number of genetic factors of human traits are single-nucleotide polymorphisms (SNPs) which are in non-coding DNA regions rather than in traditional genes. The effect of each separate SNP is unimportant, and a clear expression of the general cognitive ability is noticeable only if all the associated SNPs are involved. Currently, over 11,000 such SNPs have been identified, which are uneven in different functional regions of the genome: over 60 % in gene introns, almost 30 % in intergenic DNA regions, about 5 % in gene exons, and about 5 % in transcribed regions (downstream, upstream) and frame regions (UTR'5, UTR'3) of genes. Also there are found 74 SNPs, associated with school achievements. These SNPs are disproportionately located in genes that regulate transcription and alternative splicing of other genes, which are expressed in nerve tissues of the brain during its prenatal development. Finding genetic factors that explain the inheritance of cognitive abilities is important for both science and society. Information about these factors can be used in other fields of human science – human genetics and medicine. It will open up new scientific horizons for education too owing to understanding of the genetic aspects of learning and memory