Miracle-dz/UniFAR-FTUs huggingface dataset:
Catheter-based Cardiovascular Therapy — The Impact of Stenting in Coronary Artery Disease

Since the first application of percutaneous transluminal coronary angioplasty (PTCA) in humans in 1977, catheter-based revascularization has seen tremendous growth. The indications have been expanded; innovative technologies combined; knowledge about the pathobiology of tissue reactions increased; and new frontiers in pharmaceutical and molecular biology research chartered [31]. Now PTCA is accepted as an efficient therapy in the treatment of coronary artery disease. However, some limitations of balloon angioplasty are apparent. Such identified problems are (a) the inability to dilate resistant or elastic lesions; (b) inefficiency in controlling or preventing vessel dissection; and (c) the inability to control restenosis effectively, particularly in long lesions and after recanalization of chronic or acute (thrombotic) vessel closure. These shortcomings led to "new" devices that intended to reduce these problems. Of these new devices, coronary stenting has doubtlessly revolutionized the clinical practice of interventional cardiology by partially overcoming some of the described limitations of balloon angioplasty, particularly abrupt vessel closure and restenosis. The rate of de novo or provisional stenting in coronary catheter-based interventions has increased to more than 60%. A broad spectrum of new indications led to a reduction in surgical revascularization procedures and stimulated the widespread use of catheterbased coronary interventions, including ambulatory procedures (Table 1). The questions remain: Are these strategic approaches being subjected to properly controlled clinical trials? Or is this seemingly zealous fervor with which many practitioners support universal stent implantation based only on the allure of the immediate angiographic results and the ease of implantation [21]? Are coronary stents a breakthrough technology or just another small step [19]?
The Nigerian local chicken hormonal functional status as influenced by age and sex factors

A study was conducted to investigate the effect of age and sex on the hormonal status of the Nigerian Local Chicken raised in the Teaching and Research Farm of the Rivers State University Nkpolu-Oroworukwo, Port Harcourt. A total of forty (40) heterogeneous population of the Nigerian Local Chickens were used in a Completely Randomized Block Design (CRBD). Blood samples were collected from 10 males and 10 females from two different age groups (21 and 72 weeks). Hormonal assay was conducted to ascertain the values of some growth and reproductive hormones. These includes; thyroxin (T4), Triiodothyroxine (T3), Thyroid stimulating hormone (TSH). Prolactin (PRL), testosterone (TET), estrogen (E), luteinizing hormone (LH), follicle stimulating hormone (FSH) and progesterone (PROG). PRL, FSH, PROG and TET were significantly (p<0.05) affected by age while others were not significant (p<0.05). Prolactin had higher value for birds under the ages of 21 weeks than 72 weeks of age with a corresponding value of 28.35ng/mL and 8.64ng/mL respectively. Sex effect on hormones showed that, all hormones studied were significant except Tri-iodothyronine (T3). Testosterone as observed in this study was also influenced by age. Male birds unlike their female counterparts at 72 weeks of age recorded higher means value of 4.14 ± 0.52 than those of 21 weeks of age (1.11 ± 0.07). Therefore, the study was able to demonstrate the influence of age and sex on the status of hormones in the Nigerian Local Chicken.
TEST-TAKING STRATEGIES AND READING COMPREHENSION OF SAUDI EFL STUDENTS

There is an increasing interest in studies investigating the correlation between TestTaking Strategies (TTSs) and reading comprehension achievement among EFL learners. The relationship between the aforementioned variables is still unclear and more studies are needed in this area. The major concern of this study is to examine the correlational relationship between the use of test-taking strategies and reading comprehension. The sample of this study included 64 undergraduate students majoring in English language at King Khalid University, Saudi Arabia. The present research employed three instruments for data collection process; English Language Placement Test was used to distribute students according to their proficiency level, two reading passages taken from TOEFL reading comprehension tests, and a questionnaire adapted from Cohen and Upton (2007) asking about TTSs. The results of the present study showed that Saudi EFL students used test-taking strategies at a moderate level. There was no statistically significant correlation between test-taking strategies use and students’ achievement in reading comprehension tests. There was also no significant differences between test-taking strategies and students; achievement in reading comprehension attributed to language proficiency level. Some pedagogical implications for EFL teachers were presented and discussed.
Exploring the long-term effect of strategy work: The case of Sustainable Sydney 2030

Strategy has become an important concern and practical tool in urban management and governance, with the literature highlighting implementation as a hallmark of effective strategy. Whilst such a strategy–action link (which we label here as ‘implementation nexus’) has been well established, other long-term effects have been documented in less detail. Our study of Sustainable Sydney 2030 finds that strategy was effective to the extent to which it changed the institutional a priori of what a collective of actors engaged in city-making knows, what it can articulate and how its members relate to each other. We capture this effect as ‘institution nexus’ and theorise our findings with Ludwik Fleck’s concept of ‘thought style’ of a focal ‘thought collective’– notions that also centrally influenced Mary Douglas’ work on ‘how institutions think’. We contribute to extant research by adding the institution nexus as a long-term effect of urban strategy as well as by advancing strategy theory in urban studies to foreground its ability to shape institutions.
Original Article

1 Associate Professor, Oral & Maxillofacial Pathology, School of Dentistry, Shahid Beheshti University of Medical Sciences, Tehran, Iran 2 Assistant Professor, Department of Oral & Maxillofacial Pathology, School of Dentistry, Gilan University of Medical Sciences, Rasht, Iran 3 Professor, Proteomics Research Center, School of Rehabilitation, Shahid Beheshti University of Medical Sciences, Tehran, Iran
Don’t make a habit out of it: Impaired learning conditions can make goal-directed behavior seem habitual.

Habitual processes are often seen as the mechanisms underlying various suboptimal behaviors. Moors, Boddez, and De Houwer (2017) challenged this view, arguing that the influence of goaldirected processes may be underestimated in explaining suboptimal behavior. Much evidence for habitual processes in humans comes from studies that used an outcome devaluation test within a task called the Fabulous Fruit Game (FFG; de Wit, Niry, Wariyar, Aitken, & Dickinson, 2007). In particular, poor performance on the FFG has been taken as evidence for increased reliance on habits. Recently, however, it was shown that the outcome devaluation test in the FFG targets the wrong outcome, which likely leads to an overestimation of habitual processes (De Houwer, Tanaka, Moors, & Tibboel, 2018). We propose, in addition, that previous findings of differences in performance on the FFG do not reflect differences in habitual and goal-directed processing, but rather depend on differences in learning conditions such as task difficulty, and the opportunity, capacity, and motivation to learn the relevant contingencies. Our study shows that a lack of motivation leads to a pattern that would usually be interpreted as evidence for habits when in fact the behavior is goal-directed.
Drug utilization study in geriatric patients visiting medicine OPD in tertiary care hospital

Background: Drug utilization study is of utmost importance in the elderly. The consumption of drug amongst elderly segment of society is maximum and many of them use at least three prescribed drugs, concurrently. One of the plausible explanation of usage of large number of medicines is prevalence of multi-morbidities as well as suffer from chronic and degenerative pathology amongst them along with the alteration of pharmacokinetics and pharmacodynamics of many drugs are altered with advanced age. Thus, the aim of this study was to assess current prescribing practices among physicians for geriatric patients in tertiary care hospital. Methods: A prospective, observational and cross-sectional study was conducted in Department of Pharmacology in collaboration with Department of Medicine in a tertiary healthcare hospital. As per inclusion criteria, patients visiting Medicine outpatient department (OPD) from 01 October 2018 to 31 December 2018 were enrolled in the study. Results: The average number of drugs per encounter was 4.1. 100% of the drugs were prescribed by their generic name and those prescribed from World Health Organization (WHO) list of essential medicines were 70.2%. Analysis of polypharmacy showed maximum 11 and minimum 1 drug was prescribed. Overall analysis of the drugs showed, the most common route of administration was orally. Drugs acting on cardiovascular system (CVS), gastrointestinal system (GI) system, analgesics and anti-inflammatory drugs and vitamins and mineral supplements constitute the major bulk of drug prescribed. Conclusions: In our study, though polypharmacy was found but it was necessary unavoidable, but was within the WHO standards of 1.6 to 4.8. Drugs acting on CVS and GI system were the most common drugs prescribed. Prescriptions with injections and steroids were less in the study population. All the drugs were prescribed by their generic name and most were present in the essential list of medicines.
Glutathione S- Transferase as a Marker of Acute Kidney Injury in Pediatric Intensive Care, Zagazig University Children Hospital

Background: Glutathione S-transferases (GST) are major phase II detoxification enzymes having central roles in the cellular detoxication of a diverse group of exogenous and endogenous harmful compounds. Objective: The aim of the work was to investigate the role of GST in development of acute kidney injury in PICU, Zagazig University Children Hospital. Patients and Methods: A prospective cohort study was conducted on 50 pediatric patients admitted to PICU who were divided into two groups according to incidence of Acute Kidney Injury (AKI). Patients were subjected to clinical, laboratory, and plasma & urinary GST evaluation. Results: AKI developed in 24% of patients. There was no significant relation between presence of AKI and patient age, gender, weight, height, or clinical outcome. There were significant relations between plasma and urine GST and presence of AKI. There is statistically non-significant relation between Pediatric Risk, Injury, Failure, Loss, End-Stage renal disease (pRIFLE) staging and plasma and urine GST. There were statistically significant negative correlations between each of plasma and urine GST on one side and both heart rate and estimated creatinine clearance on the other side. Plasma GST can predict presence of AKI at cutoff ≥30.5, with AUC 0.964, sensitivity 100%, specificity 84. %, PPV 66.7%, NPV 100% , accuracy 88%. Urinary GST in prediction of AKI was ≥12.5, with AUC 0.95, sensitivity 91.7%, specificity 84.2%, with accuracy 86%. Conclusion: It could be concluded that AKI had significant incidence in PICU admission. High levels of plasma and urine GST Pi after admission in PICU are associated with an increased development of AKI and GST Pi is a valuable tool for early diagnosis of AKI.
Outcome of Spousal versus Related Donor Renal Transplantation-A Retrospective Comparative Study

Introduction: Kidney transplantation is the treatment of choice for end stage renal disease (ESRD) . Living donor transplants contribute to majority of kidney transplants in India. Objectives of the study: To assess the graft outcomes of Spousal donor (SD) transplants and to compare that with those of Related Donor (RD) transplants. Materials & methods: Adults aged 18 years or more who underwent kidney transplantation from a SD or RD between January 2010 and October 2016 were included in the present study. Patients undergoing deceased were excluded from the study. Similarly , patients undergoing a second renal transplant, those with increased cold ischemia times (greater than 6 h), non-compliant with medications and those with no follow-up were excluded from the study. Outcome data at 6 months post-transplant was collected retrospectively from 2010 to 2016. Results: A total of 211 live related renal transplants were performed at our hospital during the study period. Among those with complete follow-up (n=100) SDs constituted 30% and remaining 70 percent were parents. The recipients in the SD group were significantly older than the RD group (mean age SD 42.2 ± 8.3 years, RD 30.0 ± 9.5 years; P < 0.0001). The donors in the SD group were significantly younger (mean age SD 35.6 ± 8.2 years, RD 45.2 ± 11.5 years; P < 0.0001). Acute rejection episodes were higher in the RD group as compared to the SD group (SD 16%, RD 28.3%; P =0.01). Among SD group, rejection rates were lower in patients who received induction therapy as compared to those who did not; the difference however was not statistically significant (induction-12.3%, no-induction-18.8%; P = 0.28). There was no difference in the incidence of infective complications following transplant, between the two recipient groups. Conclusions: Outcomes of SD renal transplants are comparable to those of RD transplants. Better use of induction therapy helps in improving outcomes in these patients.
Effect of Dividend on Stock Market Price: A Panel Data Approach

Purna Man Shrestha* Abstract Dividend policy is major concern for investor, managers and policy makers. Proper dividend policy helps to achieve the wealth maximization goal of the firm. This study has examined the impact of dividend on stock market price of Nepalese enterprises. For this purpose 33 dividend paying companies listed on NEPSE has been selected as sample. Likewise, this study used unbalance panel data for the period of 2000/01 to 2018/19. Breusch and Pagan Lagrangian multiplier test concluded that Pooled regression model is not appropriate and Hausman test concluded that Random Effect model is not appropriate for the data used in this study. Thus, this study adopted Fixed Effect model to analyze the impact of dividend on stock market price. This study concluded that there is significant impact of dividend on stock market price of Nepalese enterprises after controlling return on equity, earnings per share and return on equity. Finally, this study concluded that cash dividend has significant negative and stock dividend has significant positive impact on stock market price of Nepalese enterprises.
Relationship among brand legitimacy, perceived value, re-purchase intentions and cultural inspiration: an empirical perspective. Asian J. Soc. Econ. Sci., 10(1): 01-08. http://ajses.science-line.com;

Core purpose of the study was to investigate the effects of brand legitimacy on re-patronage intentions. Study took an empirical investigation, where one hundred and eighty-four (184) valid responses were consider to measure. Social media channels were used to collect data from targeted respondents. Questionnaire were design in two languages (English & Arabic), in order to avoid inconvenience. Total four constructs, and five hypotheses were developed. To measure the considered construct items SPSS was used. It was noted after the measurement process that all the hypotheses are having significant and positive relationships. Such as, brand legitimacy impacts re-patronage intentions, brand legitimacy impacts perceiving value, perceiving value impact re-patronage intentions, perceiving value impacts cultural inspiration and cultural inspiration impacts re-patronage intentions. Original Article PII: S238309482100001-10 Rec. 24 February, 2021 Acc. 03 June, 2021 Pub. 25 June, 2021
The Effects of Allogeneic cADSCs on an Experimental Ear Auricular Defect to Evaluate Cartilage Regeneration in a Canine Model

Objective: Ear is one of the most important organs of the auditory system and may fail as a result of trauma, tumors, or other diseases. Allograft transplantation of adult stem cells has been used as an excellent procedure for restoring damage from different diseases. The aim of this study is to assess the regenerative ability of adipose-derived stem cells in ear auricle cartilage defects in a dog model injected with different treatments. Materials and Methods: The adipose-derived stem cells were isolated from canine adipose tissue. After cultured in medium, these cells were obtained after four passages. This study evaluated into three groups: Groups 1 and 2 were determined by mixing of the adipose-derived stem cells with fibrin glue biomaterial and without fibrin glue, respectively. The mixing of the adipose-derived stem cells with fibrin glue biomaterial and without fibrin glue were separately injected into the mid-portion of a surgically provided canine auricular cartilage injury. After two months, the auricular defect evaluated histologically.
Correlation of Epicardial Adipose Tissue Thickness with the Presence and Severity of Angiographic Coronary Artery Disease: a Cross Sectional Study

Background: Epicardial Adipose Tissue Thickness (EATT) has clinically correlated with abdominal fat and metabolic syndrome. The incidence of CAD is likely to increase further because of rapid urbanisation and its accompanying lifestyle changes, including changes in diet, physical inactivity, drug and alcohol intake, as well as an increase in the prevalence of DM. Objective: To correlate the Epicardial Adipose Tissue Thickness (EATT) to predict presence and severity of angiographic coronary artery disease. Materials & Methods: This was a cross sectional observational study conducted in department of General medicine at Chalmeda Anand Rao Institute of Medical Sciences, Karimnagar, India from March 2019 to March 2020. 100 consecutive patients were enrolled with age more than 18 to 75 years undergoing coronary angiography for this study. Written informed consent was obtained from all the participants. Results: In this study consisting of 100 participants participated in the study having mean age of 56.53 ± 10.46 years. Mean EATT score in obese patients found more which 12.6 with SD of 3.481 compare to Overweight and Normal patients. The cutoff value of EAT on echocardiography to diagnose significant CAD was 6.50 mm on receiver operating characteristic curve analysis with an area under the curve being 0.872 and sensitivity of 95.6% and specificity of 77.8%. Conclusion: Use of EAT thickness measurement in routine practice could be of assistance in identifying patients at risk and guiding them in proper control risk factors and, if required, undergoing evaluations with invasive approaches.
Chemical composition of cherry fruit from the cultivars Kelleris 16 and Łutówka depending on different water conditions and fertilization.

The research was conducted in 2011-2012, at the Experimental Station in Lipnik near Stargard Szczeciński, on soil classified as Haplic Cambisol, with low useful water retention. The experiment was designed with a split-plot method and repeated seven times. Grass cover was maintained in the row middles while the area underneath the trees was kept as herbicide fallow. The trees were planted in 4x2 m spacing. The assessment concerned the influence of irrigation and NK fertilisation on the dry matter and chemical composition of cherry fruit from the cultivars Kelleris 16 and Łutówka. Micro-irrigation was used at water potential in soil lower than 0.01 MPa. According to agronomic recommendations, nitrogen fertilizers were applied in early spring and potassium fertilizers in autumn in the following doses: 0 NK (control, no fertilization), 1 NK – 80 kg ha-1 (40+40), 2 NK – 160 kg ha-1 (80+80), according to agronomic recommendations. Ammonium nitrate containing 34% of nitrogen and potash salt containing 60% of potassium were used for fertilization. Observations of the irrigated trees showed an increase in the dry mass in their fruit, as well as a decrease in nitrogen, potassium and magnesium concentrations, but an increase in the amount of calcium. Chemical analyses of the fruit harvested from the trees fertilized with nitrogen and potassium demonstrated an increase in the analysed traits (macroand micronutrients), at both 1NK and 2NK fertilization levels.
Gender Differences in Attitude Toward Trauma Survivors

This research examined the relation between gender and perceptions of trauma survivors. The societal expectations of males and females differ, especially when concerning emotions (Booth, McDermott, Cheng, & Borgogna, 2019). This becomes an issue when attempting to increase trauma awareness and support efforts of those seeking help. It is necessary to recognize how each gender differs in experiencing and/or perceiving trauma. We explored the relationship between self stigma, masculinity, and empathy among male and female college students. Participants included 141 students (72.3% female; 66% Caucasian). Students reported their perceptions of trauma and responses to scales through an online survey. Independent samples t-tests and correlations provided evidence of significantly more female participants viewing the female vignette as brave. There were also significantly more male participants that viewed the female vignette as mentally weak. This data provides support for the stigma males may have towards females with trauma and mental health issues.
Melatonin: A potential therapeutic agent against COVID-19

Coronaviruses (CoVs) are RNA viruses that cause infections of the respiratory, gastrointestinal, and central nervous systems, among others. The pathological symptoms of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) include excessive inflammation, elevated oxidative stress, and an exaggerated immune response, ultimately leading to a cytokine storm and subsequent progression to acute lung injury (ALI)/acute respiratory distress syndrome (ARDS) and often, death. Melatonin is a multifunctional and highly significant biomolecule that has antiinflammatory, anti-oxidative, anti-apoptotic, and neuroprotective actions with no serious undesired side effects, even when administered in high doses. In this review, we present a brief account of the origin of coronaviruses, their characteristic features, infections, transmission, and the causes of coronavirus disease 2019 (COVID-19). We discuss their structure, genome organization, and mechanisms of cellular entry, as well as the pathogenicity of severe acute respiratory syndrome (SARS-CoV), Middle East respiratory syndrome coronavirus (MERS-CoV), and SARS-CoV-2. Furthermore, we provide an account of the typical characteristic features of melatonin, such as its antioxidant, anti-inflammatory, immunomodulatory, and ameliorative effects on various virus-induced infections. Additionally, we identify the rationale for using melatonin as both a prospective adjuvant with vaccine therapy, and as an antiviral immune stimulator. Finally, we provide a perspective on the use of melatonin as a treatment against COVID-19.