Miracle-dz/UniFAR-FTUs huggingface dataset:
Current Efforts to Make Bikeshare More Equitable: Survey of System Owners and Operators

The number of public bikeshare systems has been increasing rapidly across the United States over the past 5 to 10 years. To date, most academic research around bikeshare systems in the United States has focused on the logistics of planning and operationalizing successful systems. Investigations of system users and effects on the local community are less common, and studies that are focused on efforts to engage underserved communities in bikeshare systems are rarer still. This paper relies on a survey of representatives from 56 U.S. bikeshare systems to better understand and document current approaches toward serving low-income and minority populations. The survey asked about equity policies and metrics, the degree to which equity considerations affect a variety of system practices, what the existing barriers to utilizing bikeshare are for target populations, and what challenges the bikeshare system entity faces in addressing those barriers. Results indicate that nearly one in four bikeshare systems has written policies around equity; nearly half of bikeshare systems with more than 500 bikes have such policies. However, many more systems consider equity in various aspects of their systems. Equity considerations affected station siting, fee structure and payment systems, and promotion and marketing in a majority of systems (68%, 72%, and 57%, respectively), and operations and data collection and analysis, though to a lesser extent (42% each). Bikeshare systems reported cost, access, and outreach as the largest barriers to equity, in addition to overall funding and staff levels.
Cooperation for innovation and its impact on technological and non-technological innovations: empirical evidence for European manufacturing SMEs

We advance the notion that cooperation for innovation can demonstrate beneficial effects on firms' innovation performance. Whilst most empirical studies to date have focused on the impact of cooperation on technological product and process innovations, this study adopts a broader definition of innovation that encompasses both technological innovations and non-technological organizational and marketing innovations taking into account their complementary and interrelated nature. Drawing on a unique sample of traditional manufacturing small and medium-sized enterprises (SMEs) in seven EU regions, the study shows that cooperation for innovation increases firms' innovativeness. This conclusion is based on the positive association across the breadth of cooperation, i.e. the number of cooperative ties, with each measure of innovation outcomes, without exhibiting diminishing returns. In addition, empirical evidence suggests heterogeneous effects of individual cooperative ties on innovation performance. Overall, the results indicate that a portfolio approach to cooperation for innovation enhances innovation performance in traditional manufacturing SMEs. Finally, the findings confirm the complementary nature of technological and non-technological innovations.
Evaluation of iodate toxicity (KIO 3 ) on growth, morpho-physiological characteristics and mineral nutrients concentrations of potato ( Solanum tuberosum L. cv. Agria)

The current study was aimed to assess the effects of different iodate concentrations on morpho-physiological characteristics of potato. In this regard, a pot experiment was carried out during the spring and summer 2013. Five concentrations of KIO 3 including control beside 10, 20, 40, and 80 mg/Kg soil were applied through irrigation system. The results showed that all selected agronomical and morphological characteristics of potato except dry weight of stem (SDW) and root (RDW) were negatively affected by high iodate concentrations. The results showed that applying 80 mg KIO 3 /Kg soil compared to control resulted in around 15, 86, 84, 41, 16, 25, 20, and 87% reductions in harvest index (HI), leaf dry weight (LDW), tuber dry weight (TDW), plant dry weight (PDW), stem length (SL), root length (RL), plant height (PH), and number of tuber per plant (NT), respectively. Iodate application (80 mg KIO 3 /Kg soil vs. control) also affected potato’s physiological characteristics including chlorophyll content (SPAD), relative water content (RWC), water use efficiency (WUE), evapo-transpiration efficiency (ETE), cell membrane stability index (CMSI) and tolerance index (TI) showing around 27, 12, 87, 39, 40, and 77% reductions for each one, respectively. Increasing iodate concentrations, although, showed no effect of Zn concentration of root and Fe and Mn concentrations of leaf, gradually decreased Zn concentration of leaf and increased Fe and Mn concentrations of root and Cu concentrations of root and leaf. Plants also showed several visible symptoms including stunting, chlorosis, browning of leaf tip and reduction in growth due toxicity.
Self-regulation by Managers and Organizational Performance: On the Importance of Transcending the Managerial Role at Work

Due to their high power role, managers tend to focus on gains and organizational ideals (i.e., to adopt a promotion orientation). This management behavior is often valued by their direct environment. However, adopting a role-defined self-regulation orientation has the downside of being unilateral and may not help managers to contribute optimally to organizations facing relatively complex tasks. The current research predicts that managers who are able to transcend their role-defined promotion orientation (i.e., by adopting a prevention orientation) can have added value for organizations. A field study amongst 34 Dutch social service organizations was conducted. Self-reports concerning self-regulatory orientations of 50 managers were related to the organizational performance of the social services. As hypothesized, the ability of these managers to use a prevention orientation was positively related to indicators of organizational performance. Manager’s self-reported use of a promotion orientation was not related to these indicators. Our study is the first to show a positive relation between managers’ use of the prevention orientation and objective organizational performance. Our research suggests that organizations facing relatively complex tasks could benefit from managers who are able to transcend their role-defined promotion orientation. account for some of the inconsistencies in the Our findings suggests that managers tend to overestimate the importance of being and visionary, and may overlook the risks involved in solely focusing on this aspect of their broader responsibilities.
University The effects of 2 weeks of interval vs continuous walking training on glycaemic control and whole-body oxidative stress in individuals with type 2 diabetes

Aims/hypothesis The aim of this study was to evaluate the effects of oxygen consumption-matched short-term interval walking training (IWT) vs continuous walking training (CWT) on glycaemic control, including glycaemic variability, in individuals with type 2 diabetes. We also assessed whether any training-induced improvements in glycaemic control were associated with systemic oxidative stress levels. Methods Participants ( n =14) with type 2 diabetes completed a crossover trial using three interventions (control intervention [CON], CWT and IWT), each lasting 2 weeks. These were performed in a randomised order (computerised generated randomisation) and separated by washout periods of 4 or 8 weeks after CON or training interventions, respectively. Training included ten supervised treadmill sessions, lasting 60 min/session, and was performed at the research facility. CWT was performed at moderate walking speed (75.6%±2.5% of walking peak oxygen consumption [ 2peak O V  ]), while IWT was performed as alternating 3 min repetitions at slow (58.9% ± 2.0% 2peak O V  ) and fast (90.0% ± 3.6% 2peak O V  ) walking speed. Before and after each intervention, the following was assessed: 24 h continuous glucose monitoring (CGM) and urinary free 8-iso prostaglandin F 2α (8-iso PGF 2α ; a marker for oxidative stress), physical fitness and body composition. Neither participants nor assessors were blinded to the interventions. Conclusions/interpretation Short-term IWT, but not CWT, improves CGM-derived measures of glycaemic control independent of changes in physical fitness and body composition in individuals with type 2 diabetes. Systemic oxidative stress levels are unaffected by short-term walking and changes in oxidative stress levels are not associated with changes in glycaemic control.
GIS-based Fertility Assessment and Mapping for Agricultural Research Station, Tandur, Telangana, India

This study was conducted to determine the soil fertility status of the Agricultural Research Station, Tandur of To identify the soil sampling points, GPS device was used and collected total of 60 soil samples on grid-based method at a depth of 0–15 cm. The collected samples were analyzed for pH, EC, OC, N, P 2 O 5 , K 2 O, Zn, Cu, Fe and Mn status by following standard methods in the laboratory of Regional Agricultural Research Station, Palem, PJTSAU, Nagarkurnool District of Telangana, and Arc-GIS software was used further to prepare soil fertility maps. Around 37.5% of samples fall in neutral pH, whereas 62.5% samples were found as moderately alkaline reactions and entire farm soils were non-saline. Among the analyzed soil samples, 37.29% samples were in low organic carbon content, and rest of the samples i.e., 62.71% have medium organic carbon content and total samples were low in available N content (< 280 kg ha -1 ). The analyzed farm samples were medium to high in available phosphorus and potassium (28.67 & 71.33 % of P 2 O 5 and 16.96 & 83.04 % of K 2 O respectively) content. In contrast, the micronutrients (Zn, Cu, Fe & Mn) exceeded their sufficiency level and suggested for amelioration measures to enhance research efficacy in the farm and to build future research strategies based on the determined soil fertility status.
The inﬂuence of van der Waals forces on a bubble moving in a tube

We present a theoretical study of the unsteady thin-ﬁlm dynamics of a long bubble of negligible viscosity that advances at a uniform speed in a cylindrical capillary tube. The bubble displaces a viscous, nonwetting ﬂuid, creating a thin ﬁlm between its interface and the tube walls. The ﬁlm is considered thin enough that intermolecular forces in the form of van der Waals attractions are signiﬁcant and thin-ﬁlm rupture is possible. In the case of negligible intermolecular forces, a steady-state solution exits where a ﬁlm of uniform thickness is deposited in the annular region between the bubble interface and the tube walls. However, once intermolecular interactions are important, the interface is perturbed out of its steady state and either (i) the perturbation grows suﬃciently before reaching the rear meniscus of the bubble such that rupture occurs; or (ii) the perturbation remains small due to weak intermolecular forces until it leaves the bubble interface through the rear meniscus. We obtain, both numerically and asymptotically, the time-scale over which rupture occurs, and thus, we ﬁnd a critical capillary number, depending on the bubble length and the strength of the intermolecular forces, below which the ﬁlm is predicted to rupture.
Redeﬁning Escherichia coli (cid:1) 70 Promoter Elements: (cid:2) 15 Motif as a Complement of the (cid:2) 10 Motif (cid:1) †

Classical elements of (cid:1) 70 bacterial promoters include the (cid:2) 35 element ( (cid:2) 35 TTGACA 30 ), the (cid:2) 10 element ( (cid:2) 12 TATAAT (cid:2) 7 ), and the extended (cid:2) 10 element ( (cid:2) 15 TG (cid:2) 14 ). Although the (cid:2) 35 element, the extended (cid:2) 10 element, and the upstream-most base in the (cid:2) 10 element ( (cid:2) 12 T) interact with (cid:1) 70 in double-stranded DNA (dsDNA) form, the downstream bases in the (cid:2) 10 motif ( (cid:2) 11 ATAAT (cid:2) 7 ) are responsible for (cid:1) 70 –single-stranded DNA (ssDNA) interactions. In order to directly reﬂect this correspondence, an extension of the extended (cid:2) 10 element to a so-called (cid:2) 15 element ( (cid:2) 15 TGnT (cid:2) 12 ) has been recently proposed. I investigated here the sequence speciﬁcity of the proposed (cid:2) 15 element and its relationship to other promoter elements. I found a previously undetected signiﬁcant conservation of (cid:2) 13 G and a high degeneracy at (cid:2) 15 T. I therefore deﬁned the (cid:2) 15 element as a degenerate motif, which, together with the conserved stretch
Edinburgh Explorer Relationship of Platelet Reactivity With Bleeding Outcomes During Long-Term Treatment With Dual Antiplatelet Therapy for Medically Managed Patients With Non-ST-Segment Elevation Acute Coronary Syndromes

Background- — The relationship between “ on-treatment ” low platelet reactivity and longitudinal risks of major bleeding dual antiplatelet therapy following acute coronary syndromes remains uncertain, especially for patients who do not undergo percutaneous coronary intervention. Methods and Results- — We analyzed 2428 medically managed acute coronary syndromes patients from the Targeted Platelet Inhibition to Clarify the Optimal Strategy to Medically Manage Acute Coronary Syndromes (TRILOGY ACS) trial who had serial platelet reactivity measurements (P2Y 12 reaction units; PRUs) and were randomized to aspirin + prasugrel versus aspirin + clopidogrel for up to 30 months. Contal ’ s method was used to determine whether a cut point for steady-state PRU values could distinguish high versus low bleeding risk using 2-level composites: Global Use of Strategies to Open Occluded Coronary Arteries (GUSTO) severe/life-threatening or moderate bleeding unrelated to coronary artery bypass grafting (CABG) and non-CABG Thrombolysis In Myocardial Infarction (TIMI) major or minor bleeding.Exploratoryanalysesused3-levelcompositesthatincorporatedmildandminimalGUSTOandTIMIevents.ContinuousmeasuresofPRUs(per10-unitdecrease)werenotindependentlyassociatedwiththe2-levelGUSTO(adjustedhazardratio[HR],1.01;95%CI,0.96 – 1.06) or TIMI composites (1.02; 0.98 – 1.07). Furthermore, no PRU cut point could signi ﬁ cantly distinguish bleeding risk using the 2-level composites.However,thePRUcutpointof75differentiatedbleedingriskwiththe3-levelcompositesofGUSTO(26.5%vs12.6%;adjustedHR,2.28;95%CI,1.77 – 2.94; P < 0.001) and TIMI bleeding events (25.9% vs 12.2%; adjusted HR, 2.30; 95% CI, 1.78 – 2.97; P < 0.001). Conclusions- — Among medically managed non-ST-segment elevation acute coronary syndromes patients receiving prolonged dual antiplatelet therapy, PRU values were not signi ﬁ cantly associated with the long-term risk of major bleeding events, suggesting that low on-treatment platelet reactivity does not independently predict serious bleeding risk.
Better bound on the exponent of the radius of the multipartite separable ball (12 pages)

We show that for an m-qubit quantum system, there is a ball of radius asymptotically approaching {kappa}2{sup -{gamma}}{sup m} in Frobenius norm, centered at the identity matrix, of separable (unentangled) positive semidefinite matrices, for an exponent {gamma}=0.5(ln 3/ln 2-1){approx_equal}0.292 481 25 much smaller in magnitude than the best previously known exponent, from our earlier work, of 1/2. For normalized m-qubit states, we get a separable ball of radius {radical}(3{sup m+1}/(3{sup m}+3))x2{sup -(1+{gamma}}{sup )m}{identical_to}{radical}(3{sup m+1}/(3{sup m}+3))x6{sup -m/2} (note that {kappa}={radical}(3)), compared to the previous 2x2{sup -3m/2}. This implies that with parameters realistic for current experiments, nuclear magnetic resonance (NMR) with standard pseudopure-state preparation techniques can access only unentangled states if 36 qubits or fewer are used (compared to 23 qubits via our earlier results). We also obtain an improved exponent for m-partite systems of fixed local dimension d{sub 0}, although approaching our earlier exponent as d{sub 0}{yields}{infinity}.
Dowling M (2016) Influences on quality of prescribing in breast cancer patients. Nurse Prescribing, 14 (10):448-452.

This paper presents a discussion on both positive and negative influences on quality of prescribing in clinical practice. It explores how such influences impact on breast cancer patients on adjuvant hormonal therapy. Nurse prescribing is a relatively new development within nursing in Ireland and continues to develop. Guiding the registered prescribing nurse in practice, prescribing duties are undertaken in line with a dual framework incorporating both legislative and professional mandates. Though these guidelines serve to direct and ensure quality prescribing, no governing mandate meets all the complexities and challenges faced in clinical practice. This paper critically analyses how differing factors impact on the process of quality prescribing for breast cancer patients on adjuvant hormonal therapy. Factors explored include the prescriber, patient, illness, also the healthcare setting and economics. Since hormonal therapy in the adjuvant setting for breast cancer patients is associated with a reduction in both recurrence and mortality rates. The impact of quality prescribing can result in a meaningful long term outcome for this particular group of patients.
LSHTM Research Online Density and Infectivity in and of

Forty-word summary: Plasmodium falciparum gametocyte skin sequestration has long been hypothesized but never formally tested. We observed no evidence for higher gametocyte densities in skin tissue of naturally infected gametocyte carriers or blood meals of mosquitoes feeding on their skin. ABSTRACT Background. Plasmodium falciparum transmission depends on mature gametocytes that can be ingested by mosquitoes taking a bloodmeal on human skin. Although gametocyte skin sequestration has long been hypothesized as important contributor to efficient malaria transmission, this has never been formally tested. Methods . In naturally infected gametocyte carriers from Burkina Faso, we assessed infectivity to mosquitoes by direct skin feeding and membrane feeding. We directly quantified male and female gametocytes and asexual parasites in: i) finger prick blood, ii) venous blood, iii) skin biopsies, and in pools of mosquitoes that fed iv) on venous blood or, v) directly on skin. Gametocytes were visualized in skin tissue by confocal microscopy. Results. Whilst more mosquitoes became infected when feeding directly on the skin compared to venous blood (odds ratio 2.01; 95% CI 1.21 – 3.33, p = 0.007), concentrations of gametocytes in the subdermal skin vasculature were not higher compared to other blood compartments; only sparse gametocytes were observed in skin tissue. Discussion. Our data strongly suggest that there is no significant skin sequestration of P. falciparum gametocytes. Gametocyte densities in peripheral blood are thus informative for predicting onward transmission potential to mosquitoes and can be used to target and monitor malaria elimination initiatives.
Infertility among Women Accessing Care in Selected Fertility Clinics in Port Harcourt, Nigeria

This study examined infertility among women accessing care in selected fertility clinics in Port Harcourt. The study was a descriptive survey of selected fertility clinics in Port Harcourt. The target population included all women on fertility treatment in the clinics during the period of conducting the study (March to June 2019) which totaled 362. The entire population was used in the study; hence the total sampling technique was employed. A structured scale with a reliability index of 0.82 reflecting the study variables was used as the data collection instrument. Analysis of data from field survey was done using descriptive and inferential statistics. The Statistical Package for Social Sciences (SPSS) version 22 was employed in the data analytical process. And results were presented in tables. Results revealed that out of the 362 respondents studied, 156(43.0%) were experiencing primary infertility while 206(57.0%) had secondary infertility problems; of all causes of infertility among women, uterine problems contribute 10%, tubal disorders 22%, ovulation problems, 60% and unknown causes, 8%; that there is a significant relationship between age and experience of infertility among women (>0.05). The study concludes that there is a higher incidence of secondary than primary infertility among women. The need for women of child bearing age to be educated on the factors associated with secondary infertility and the measures that can be taken to prevent its occurrence is recommended.
Relationship of facial type and nasopalatine canal course

The aim of this study was to describe the course of the nasopalatine canal, the adjacent vertical bone quantity, and whether it might differ among vertical facial types using cone beam computed tomography (CBCT) scans. linear measurements were perpendicular to the palate at the level of 1 st molar/2 nd premolar (5/6), 2 nd premolar/1 st premolar (4/5), and 1 st premolar/canine (3/4). Screen-prints were used to measure the inclination of the nasopalatine canal in relation to the maxillary jaw base. Maxillary and mandibular divergence was assessed on
Modeling Localization and Failure with High-order Finite Elements

This thesis presents a consistent modeling approach to the phenomenon of deformation localization and material failure, based on high-order finite elements. Strong discontinuities are incorporated into the finite element formulation in an embedded manner. As opposed to previous concepts, the presented approach is consistently deduced regarding its possible application in the context of high-order finite elements. Put forth by a novel reassessment of the strong discontinuity kinematics, an extended p-adaptive formulation is established. Three-dimensional numerical investigations show that the proposed approach facilitates a minimization of potential locking effects. Compared to a corresponding low-order approach, a significantly enhanced numerical resolution of the failure process can be observed.
Cross-Linking of CD4 Molecules Upregulates Fas Antigen Expression in Lymphocytes by Inducing Interferon-y and Tumor Necrosis Factor-cu Secretion

We have recently shown that, in unfractioned peripheral blood mononuclear cells (PBMCs), the cross-linking of CD4 molecules (CD4XL) is sufficient to induce T-cell apoptosis. However, the underlying mechanism for the CD4XL-medi-ated T-cell apoptosis is largely unknown. Several recent studies have shown that Fas antigen (Ag), a cell-surface molecule, mediates apoptosis-triggering signals. We show here that cross-linking of CD4 molecules, induced either by anti-CD4 monoclonal antibody (MoAb) Leu3a or by human immunodeficiency virus-l (HIV-1) envelope protein gp160, upregulates Fas Ag expression as well as Fas mRNA in normal lymphocytes. Addition of the tyrosine protein kinase inhibitor genistein or of the immunosuppressive agent cyclosporin A abrogated these effects. The upregulation of TNF-u were found to contribute to Fas Ag upregulation and both anti-INF-y and anti- TNF-(u antibodies blocked CD4XL-induced Fas Ag upregulation and lymphocyte apoptosis. These findings strongly sug- gest that aberrant cytokine secretion induced by CD4XL and consequent upregulation of Fas Ag expression might play a critical role in triggering peripheral T-cell apoptosis and thereby contribute to HIV disease pathogenesis.