Miracle-dz/UniFAR-FTUs huggingface dataset:
COMPARATIVE ANALYSIS OF DRY AND WET PROCESSING OF COFFEE WITH RESPECT TO QUALITY AND COST IN KAVRE DISTRICT, NEPAL: A CASE OF PANCHKHAL VILLAGE

A study was conducted at Panchkhal Village Development Committee (VDC) in Kavre district to compare and analyze two processing methods (dry and wet methods) with respect to quality and benefit cost ratio. A total of 30 respondents (farmers, processors, traders and consumers) were selected during survey whereas 7 coffee chain actors (except a local roaster) out of 30 respondents were chosen for in depth case studies. Results showed that there was significant difference in quality of coffee based on cup taste test (at 5% significance level, p=0.001). The average moisture content of coffee bean taken from different lots from dry processing method was found to be 12.83% which was higher than the standard commercial moisture range (9-12%) recommended by the International Coffee Organization (ICO). Moisture content (2.66) and flavour (2.3) are the major determinants of coffee quality according to quality attribute importance index. Depulping and fermentation was the most important coffee processing step followed by cherry sorting and grading determining the coffee quality. Knowledge and training was the major influencing factor for quality coffee production followed by supply of quality input. Benefit cost ratio for dry method was found to be higher (1.4) than wet method (1.2). Similarly, 40% respondents considered that inaccessibility to credit is the main reasoning factor behind adoption of two processing methods among farmers. These results could also be helpful in implementing the programs and formulating policies based on farmers need and capacity in order to improve the quality of coffee for export market.
The therapeutic use of the zonulin inhibitor AT-1001 (Larazotide) for a variety of acute and chronic inflammatory diseases.

BACKGROUND The involvement of intercellular tight junctions and, in particular, the modulation of their competency by the zonulin pathway with a subsequent increase in epithelial and endothelial permeability, has been described in several chronic and acute inflammatory diseases. In this scenario, Larazotide, a zonulin antagonist, could be employed as a viable therapeutic strategy. OBJECTIVE The present review aims to describe recent research and current observations about zonulin involvement in several diseases and the use of its inhibitor Larazotide for their treatment. METHODS A systematic search was conducted on PubMed and Google Scholar, resulting in 209 publications obtained with the following search query: "Larazotide," "Larazotide acetate," "AT-1001," "FZI/0" and "INN-202. " After careful examination, some publications were removed from consideration because they were either not in English or were not directly related to Larazotide. RESULTS The obtained publications were subdivided according to Larazotide's mechanism of action and different diseases: celiac disease, type 1 diabetes, other autoimmune diseases, inflammatory bowel disease, Kawasaki disease, respiratory (infective and/or non-infective) diseases, and other. CONCLUSIONS A substantial role of zonulin in many chronic and acute inflammatory diseases has been demonstrated in both in vivo and in vitro, indicating the possible efficacy of a Larazotide treatment. Moreover, new possible molecular targets for this molecule have also been demonstrated.
TALPID 3 controls centrosome and cell polarity and the human ortholog KIAA 0586 is 1 mutated in Joubert syndrome ( JBTS 23 ) 2 3

Citation for published version: Stephen, LA, Tawamie, H, Davis, GM, Tebbe, L, Nürnberg, P, Nürnberg, G, Thiele, H, Thoenes, M, Boltshauser, E, Uebe, S, Rompel, O, Reis, A, Ekici, AB, McTeir, L, Fraser, AM, Hall, E, Mill, P, Daudet, N, Cross, C, Wolfrum, U, Jamra, RA, Davey, MG & Bolz, HJ 2015, 'TALPID3 controls centrosome and cell polarity and the human ortholog KIAA0586 is mutated in Joubert syndrome (JBTS23)', eLIFE, vol. 4, no. September. https://doi.org/10.7554/eLife.08077
Consumer Interest in Commercial Applications of Body Scan Data

Three dimensional body scan technology is being targeted for utilization in the apparel industry, specifically for automated custom fit, size and fit prediction, virtual try-on, personal shopper services, co-design mass customization, custom pattern development for home sewers, and research. But the ultimate success of commercial applications of body scan data will be consumer acceptance and use of the applications. In this study, we surveyed a sample of 203 women 34-55 years of age about their interest in these six commercial and apparel research applications after they were scanned. The results indicated high interest by over 80% of the sample in virtual try-on, size prediction, custom fit, and personal shoppers. When asked to select the application of highest appeal, virtual try-on was selected by 35% of the sample while custom fit, size prediction, and personal shopper applications were selected by 15-16% each. Women with dissatisfaction with ready-to-wear pant fit, higher incomes, and Internet buyers were significantly more likely to look for and purchase clothing on the Internet if these scan-based applications were available commercially. Recommendations are made for future experimental and focus group research to study how consumer interest in adopting these applications could be stimulated.
Temperament, environment, and antisocial behavior in a population sample of preadolescent boys and girls

Antisocial behavior can be triggered by negative social experiences and individuals' processing of these experiences. This study focuses on risk-buffering interactions between temperament, perceived parenting, socio-economic status (SES), and sex in relation to antisocial behavior in a Dutch population sample of preadolescents (N = 2230). Perceived parenting (overprotection, rejection, emotional warmth) was assessed by the EMBU (a Swedish acronym for My Memories of Upbringing) for children, temperament (effortful control and frustration) by the parent version of the Early Adolescent Temperament Questionnaire-Revised, SES by information on parental education, occupation, and income, and antisocial behavior by the Child Behavior Checklist (parent report) and the Youth Self-Report (child report). All parenting and temperament factors were significantly associated with antisocial behavior.The strongest risk-buffering interactions were found for SES which was only related to antisocial behavior among children with a low level of effortful control or a high level of frustration. Furthermore, the associations of SES with antisocial behavior were more negative for boys than for girls. Thus, the effects of SES depend on both the temperament and sex of the child.
Effects of Social Media Interaction on Self-Esteem among Students in Public Secondary Schools in Nairobi County, Kenya

: Adolescents are part of the generation that is growing up in a time when digital technology is rapidly expanding. Therefore, social media interaction has become a way of living for adolescents who are experiencing rapid changes in their development. Part of the changes experienced is a result of the desire for independence and search for self-identity. Self-esteem is part of self-identity. There is uncertainty about how social media interaction impacts adolescents' self-esteem. Therefore, this article investigated the effects of social media platforms on self-esteem among high school students in public secondary schools in Nairobi County, Kenya. The study employed a descriptive survey research design. A sample size of 379 respondents was obtained through stratified and simple random sampling. A structured questionnaire assisted in data collection. SPSS version 20 was employed to assist in data analysis. Descriptive statistics were obtained and presented in tables. The linear regression model was used to predict the effect of social media interactions on self-esteem. The model was significant F (1, 344) =2.662, p-value >. 05. The coefficient of self-esteem based on social media interaction showed that the regression weight was not statistically significant ( p> .05). The output showed social media interaction does not affect students’ self-esteem ( β = .088, t = 19.934, p> .05). It is essential that training is provided to parents, educators, and students to improve their skills and knowledge on digital media, as social media is a powerful resource that can be utilized in schools and at home to support social development. ‘increase in social media usage causes the self-esteem of individuals to decrease. One hour spent on Facebook daily results in a 5.574 decrease in the self-esteem score of an individual’ (p.336). Jan et al (2017) used both questionnaires and interviews, which are the instruments the current study is using. Some studies seem to imply that the use of social media platforms is of more benefit to adolescents with low self-esteem. For example, Ellison et al (2007) asserted that teenagers with lower self-esteem find social media beneficial and in particular Facebook compared to those with higher self-esteem. Their findings were supported by Tazghini and Siedlecki who found the same thing. Similarly, Shaw and Gant noted that online communication can heighten social support that on the other hand reduces imagined loneliness and dejected emotions thereby growing self-esteem. Australian Research Alliance for Students and Youth supports that ‘Students and youth who are loved and safe are confident, have a strong sense of self-identity, and have high self-esteem’ (p.8).
Title Reprogramming Roadblocks Are System Dependent

Author(s) Chantzoura, Eleni; Skylaki, Stavroula; Menendez, Sergio; Kim, Shin-Il; Johnsson, Anna; Linnarsson, Sten; Woltjen, Knut; Chambers, Ian; Kaji, Keisuke Citation Stem Cell Reports (2015), 5(3): 350-364 Issue Date 2015-09-08 URL http://hdl.handle. net/2433/226438 Right © 2015 The Authors. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/). Type Journal Article Textversion publisher
TOPFARM - next generation design tool for optimisation of wind farm topology and operation

The present report is the publishable final activity report for the EU project TOPFARM. The project has been running from 1st December 2007 to 30th November 2010, and has successfully addressed optimization of wind farm topology and control strategy based on aero-elastic modeling of loads as well as of power production as seen in an economical perspective. Crucial factors in this regard are the overall wind climate at the wind farm site, the position of the individual wind turbines, the wind turbine characteristics, the internal wind farm wind climate, the wind turbine control/operation strategy for wind turbines interacting through wakes, various cost models, the optimization strategy and a priori defined constraints imposed on the wind farm topology. In TOPFARM, the object function used in the optimization platform is formulated in economical terms, thus ensuring the optimal balance between capital costs, operation and maintenance costs, cost of fatigue lifetime consumption and power production output throughout the design lifetime of the wind farm. The report describes the project consortium and the project activities, which has been organized in 9 Work Packages. A summary description of the results is given, and reference is made to a large number of publications resulting from the project.
MERIT-Infonomics Research Memorandum series ICT-Investment, Knowledge Accumulation and Endogenous Growth

In this paper we present an endogenous growth model based on Lucas (1988). We have extended the Lucas model by incorporating ICT-capital next to human capital. We take account of spillovers from ICT use in human capital formation to final output production. The effects on growth of these spillovers depend very much on whether they are external or completely internalised. We find that welfare is positively affected, the stronger these spillovers are, but also the more these spillovers are internalised. In addition, we find that in the case of limited internalised knowledge spillovers, we may face a multiple equilibria steady state growth situation, that has an inherent tendency to select the non-optimum (high growth) equilibrium in which all types of capital are ‘over accumulated’, including ICT-capital. This suggests that there is room for policy intervention here, because there exists an ‘optimum’ value of the knowledge-spillover parameter where both equilibria coincide and over accumulation does not happen. Adriaan van Zon, MERIT, Maastricht University Phone: +31 43 3883890, Fax: +31 43 3884905 e-mail: Adriaan.vanZon@Merit.Unimaas. NL
Design and evaluation of network coding in a P 2 P VoD system

To measure the impact of Network Coding on classical P2P systems, we have designed and added a Network Coding module in an existing P2P-VoD system called PPlayer. As we worked in a micro environment we got more focused on the influence of Network Coding on individual peer rather than on the overall system throughput. However, the tests performed in our laboratory have highlighted some advantages. With equal performances, less data are sent on the network and slow peers can help to provide data. But Network Coding implies a heavy computing complexity which is an obstacle in the deployment of Network Coding at a large scale. To deal with it we propose two solutions: the generation of half decoded blocks and a buffering system allowing a peer to provide more peer at the same time. Summary
Multivariate Submodular Optimization

Submodular functions have found a wealth of new applications in data science and machine learning models in recent years. This has been coupled with many algorithmic advances in the area of submodular optimization: (SO) $\min/\max~f(S): S \in \mathcal{F}$, where $\mathcal{F}$ is a given family of feasible sets over a ground set $V$ and $f:2^V \rightarrow \mathbb{R}$ is submodular. In this work we focus on a more general class of \emph{multivariate submodular optimization} (MVSO) problems: $\min/\max~f (S_1,S_2,\ldots,S_k): S_1 \uplus S_2 \uplus \cdots \uplus S_k \in \mathcal{F}$. Here we use $\uplus$ to denote disjoint union and hence this model is attractive where resources are being allocated across $k$ agents, who share a `joint' multivariate nonnegative objective $f(S_1,S_2,\ldots,S_k)$ that captures some type of submodularity (i.e. diminishing returns) property. We provide some explicit examples and potential applications for this new framework. For maximization, we show that practical algorithms such as accelerated greedy variants and distributed algorithms achieve good approximation guarantees for very general families (such as matroids and $p$-systems). For arbitrary families, we show that monotone (resp. nonmonotone) MVSO admits an $\alpha (1-1/e)$ (resp. $\alpha \cdot 0.385$) approximation whenever monotone (resp. nonmonotone) SO admits an $\alpha$-approximation over the multilinear formulation. This substantially expands the family of tractable models for submodular maximization. For minimization, we show that if SO admits a $\beta$-approximation over \emph{modular} functions, then MVSO admits a $\frac{\beta \cdot n}{1+(n-1)(1-c)}$-approximation where $c\in [0,1]$ denotes the curvature of $f$, and this is essentially tight. Finally, we prove that MVSO has an $\alpha k$-approximation whenever SO admits an $\alpha$-approximation over the convex formulation.
Retinoblastoma protein promotes uterine epithelial cell cycle arrest and necroptosis for embryo invasion

Retinoblastoma protein (RB) encoded by Rb1 is a prominent inducer of cell cycle arrest (CCA). The hormone progesterone (P4) promotes CCA in the uterine epithelium and previous studies indicated that P4 activates RB by reducing the phosphorylated, inactive form of RB. Here, we show that embryo implantation is impaired in uterine‐specific Rb1 knockout mice. We observe persistent cell proliferation of the Rb1‐deficient uterine epithelium until embryo attachment, loss of epithelial necroptosis, and trophoblast phagocytosis, which correlates with subsequent embryo invasion failure, indicating that Rb1‐induced CCA and necroptosis of uterine epithelium are involved in embryo invasion. Pre‐implantation P4 supplementation is sufficient to restore these defects and embryo invasion. In Rb1‐deficient uterine epithelial cells, TNFα‐primed necroptosis is impaired, which is rescued by the treatment with a CCA inducer thymidine or P4 through the upregulation of TNF receptor type 2. TNFα is expressed in the luminal epithelium and the embryo at the embryo attachment site. These results provide evidence that uterine Rb1‐induced CCA is involved in TNFα‐primed epithelial necroptosis at the implantation site for successful embryo invasion.
Detection and Bloody Profiles Evaluation of Naturally Infected Camels with Subclinical Trypanosoma evansi, Iraq

The current study directs for detection the molecular-prevalence of Trypanosoma evansi in naturally subclinical infected camels by PCR assay, in addition to establishment a reference values for blood parameters of study animals. During of April to November/2018, the total results for testing 92 venous blood samples were revealed on 27.17% T. evansi positive camels. Among T. evansi infected camels, significant increases (P0.05) were detected in age factor at 1-4 years group; whereas, no significant variation (P>0.05) was showed between groups of areas and gender factors. Concerning to hematology, significant decreases were showed in total RBCs, Hb, and MCHC; with significant increases in MCV and MCH. For leukocytes, significant increases were showed in total WBCs and lymphocytes only. In serum-biochemical indices, significant decreases (P0.05) were observed in albumin, albumin/globulin ratio, as well as in glucose; and significant increases in AST, ALT, GGT, ALP, CK, total protein, and globulins; but neither in BUN nor total bilirubin. For serum-minerals, significant decrease and significant increase were recorded respectively in iron and phosphorus; however, no significant differences were detected in calcium, magnesium, sodium, and potassium. In clotting factors, the findings were revealed on significant decreases in platelet and fibrinogen concentration, with significant increases in ACT, Prt, and Aptt. However, MPV and PDW were appeared without significant variation.
Reaction Pathways for the Deoxygenation of Biomass‐Pyrolysis‐Derived Bio‐oil on Ru: A DFT Study using Furfural as a Model Compound

Fast pyrolysis is emerging as a promising route for the production of liquid fuels from biomass. However, pyrolysis‐derived bio‐oil needs to be upgraded prior to its utilization as a fuel and hydrodeoxygenation (HDO) is an important catalytic step for its upgrade. Design of suitable catalysts with high activity and selectivity for the HDO process requires detailed understanding of the underlying catalytic reaction mechanism. As ruthenium (Ru)‐based catalysts have been proposed to be the most effective HDO catalysts, the complete reaction network for HDO of furfural, a representative of furanic compounds present in bio‐oil, is elucidated in this study on the Ru(0 0 1) surface by using first‐principles density functional theory calculations. The reaction pathways for the formation of furfuryl alcohol (FA), tetrahydrofurfuryl alcohol (THFA), methyltetrahydrofuran (MTHF), methylfuran (MF), cyclopentanol, 1,2‐ and 1,5‐pentane diols, furan, and pentanes are established. Furan ring‐opening is facile on Ru surfaces and our calculations predict pentane formation to be thermodynamically and kinetically favored in the vapor‐phase hydrodeoxygenation of furfural on Ru surfaces.
Long-memory in asset returns and volatility: evidence from West Africa

This paper measures the degree of long-memory or long-range dependence in asset returns and volatility of two stock indices in Ghana and Nigeria. The presence of long-memory opens up opportunities for abnormal returns to be made by analyzing price history of a particular market. The authors employ the Hurst exponent to measure the degree of long-memory which is evaluated by a semiparametric method, the Local Whittle estimator. The ﬁndings show strong evidence of the presence of long-memory in both returns and volatility of the indices studied, suggesting that neither of the markets in Ghana and Nigeria is weak-form e (cid:421)
Unemployment Protection and Labour Market Reform in France and Great Britain in the 1990s: Solidarity Versus Activation?

Standard accounts of unemployment protection and labour market policy reform tend to put France and the UK at opposing ends of the spectrum of values and policy directions in Europe. British efforts in the 1990s of switching emphasis from ‘passive’ benefit payment towards promoting participation in ‘active’ programmes of labour market integration are widely understood as a product of liberalism, individualism and increasing labour market flexibility, introducing a degree of workfare into the overall structure of unemployment support. By contrast, in France the resistance of traditional values and a ‘social treatment of unemployment’ are often portrayed as having put a brake on labour market reform and retrenchment of unemployment protection. After a reflection on the respective national discourses, the article challenges this view and points to a more complex reality that includes not only acknowledgement of labour market differences but also trends of convergence and counterintuitive developments. Secondly, it claims that in the 1990s Britain and France have both moved increasingly towards an unemployment policy based on activation, but in forms which reflect, to a great extent, different political incentive structures. The political implications of differentially institutionalised interests have in this way driven unemployment policy in different, but not opposing, directions. Recognition of this more nuanced reality should enable a better theoretical understanding of the social and political conditions for successful activation policies.
The practice of job crafting and its impact on job outcomes

This study aims to investigate the effect of job crafting practices on job outcomes (work engagement and job satisfaction). This research was conducted on workers at Perseroan Terbatas (PT). Petra Arun Gas (PAG) with a working population of 180 people. Samples were taken as many as 123 people based on Krejcie and Morgan Sample Tables (in Sekaran & Bougie, 2009, pp. 254-255). The selection of sample members was carried out using the simple random sampling method. Primary data is obtained by distributing questionnaires to all samples. Data were analyzed using simple linear regression analysis tools with the help of SPSS. The results of the research data analysis show that job crafting has a significant effect on the two dependent constructs, namely work engagement and job satisfaction.