Miracle-dz/UniFAR-FTUs huggingface dataset:
To Assess the Efficacy and Safety of Various Anti-heliminthics against Ascariasis Lumbricoides among a Study Population in North India

Copyright © 2018 Phcog.Net. This is an openaccess article distributed under the terms of the Creative Commons Attribution 4.0 International license. Cite this article: Kawoosa Z, Javid G, Yattoo GN, Gulzar GM, Sodhi JS, Shah AH, Khan M, Hamid S. To Assess the Efficacy and Safety of Various Anti-heliminthics against Ascariasis Lumbricoides among a Study Population in North India. OGH Reports. 2018;7(1):25-34. ABSTRACT Introduction: More than 24% of the world’s population, are infected with soil-transmitted helminth infection. Aim: To assess the helminthic load & efficacy and safety of various antiheliminthics. Methods: A total of 400 patients who met the inclusion criteria were recruited after proper consent. Subjects were divided into Four groups (100 each) randomly & receive different antihelminthic drugs. Cure rate and egg reduction rate was used as a primary outcome measure. Three weeks later two more stool samples were analyzed by two methods 1) Direct Smear method & 2) Concentration method. On follow-up, each group were randomly assigned a single dose of albendazole (single 400 mg dose), mebendazole (100 mg, BD×3 days), pyrantel pamoate (11 mg/kg orally once) and ivermectin (0.2 mg/kg orally once) using a randomization procedure.The data was statistically analysed. Observations: Among 400 patients, 63% were 5-19 years of age, 68% were male, 73.5% were from rural areas, 71% were literate, 62% were in the low income group, 58% reported closed sanitation, 6.75% were having low BMI, 26.25% were having High Absolute Eosinophilic Count before treatment, 77.5% were non-anaemic. 92.5% did not have icterus. In the present study it was seen that the difference among the four drugs was statistically significant as per demographic variables. Significant decrease of worm load after treatment were comparable with each other. However, Presence of Worm across papillae seen after upper GI endoscopy and persistent biliary ascariasis was comparable in all the four drug groups. Overall, the efficacy of anthelmintic drugs was excellent and statistically significant (p<0.001). Conclusion: Albendazole and mebendazole having cure rates of 90% and also reducing the mean egg count by 90%. Also treatment of school children every 4 monthly may be necessary in high endemic areas, like ours. All these drugs which we used in our study are safe and no significant side effects were observed.
Effects of land cover type on community structure and functional traits of alpine stream benthic macroinvertebrates

In the European Alps, due to the current changes in land use driven by different social and economic factors, grasslands and pastures are being increasingly replaced by forests. Whereas many studies have focused on the impacts of urbanisation and intensive agricultural activities, no study has evaluated the effects of changes among types of natural to semi‐natural land cover in the Alps with a focus on lotic environments. Here, combining taxonomic and functional approaches, we show the effects of four different alpine land cover types (rocks, grasslands, coniferous forests, valley bottom pastures) on stream benthic macroinvertebrate communities. Irrespective of elevation, grasslands and pastures exhibited unpredicted similarity in terms of the composition of the macroinvertebrate assemblages and hosted the highest diversity of benthic organisms, whereas in each of the other land cover types, the density and diversity of the faunal assemblages showed distinct and characteristic values. When analysing the functional diversity decomposed to richness, evenness, and divergence components, grasslands and pastures again showed a similar trend, being characterised by high levels of resource exploitation and niche differentiation, with the potential to host additional organisms. However, as expected, differences driven by land cover type and elevation emerged when examining the single functional traits, since elevation played a major role in terms of the distribution of traits conferring resistance and resilience. Our results demonstrate that land cover type is a prominent factor influencing the taxonomic and functional variety of stream benthic macroinvertebrate communities. Moreover, alpine grasslands contained an unexpected diversity of aquatic insects, as previously assessed for other organisms (e.g. plants and snails). Overall, our study highlights the importance of the preservation of the diversity of habitats in the alpine region, with a special focus needed for valuable semi‐natural landscapes, such as grasslands and pastures, particularly in a time of increasing intensification and abandonment of lands in the alpine context.
Comparison of laryngeal mask airway supreme™ versus endotracheal intubation in positive pressure ventilation with muscle relaxant for intraoperative and postoperative conditions

Background: Laryngeal Mask Airways are increasingly being used now a day as an option to endotracheal intubation, as it is less invasive and causes less discomfort in the postoperative period. The aim of this study was to evaluate the clinical use of the laryngeal mask airway Supreme in patients undergoing elective gynaecological surgeries under general anaesthesia and compare it with endotracheal intubation. Methods: 60 ASA I and II females, having BMI <30kg.m in the range of 20-50 years of age, scheduled for elective gynaecological surgeries were randomly allocated to one of the two groups according to the device used (LMAS or ETT). Time required for insertion, number of attempts, hemodynamic response to insertion/removal and incidence of immediate and late postoperative complications such as coughing, laryngospasm, sore throat, dysphagia etc. were assessed. Results: Number of attempts for successful insertion was similar but time required for LMA SupremeTM insertion was significantly less (25.40±12.90 versus 33.27±14.82 sec) similarly, time required for nasogastric tube insertion was significantly more in ETT group (30.28±16.22 versus 21.93±12.64 sec). No episode of failed ventilation or hypoxia was recorded. The changes in hemodynamic parameters were significantly higher after endotracheal intubation and during extubation. Incidence of postoperative complications was significantly higher after endotracheal intubation (p<0.05). Conclusions: The LMA SupremeTM is a suitable alternative to endotracheal intubation during general anaesthesia for elective gynaecological surgeries with the added advantage of less hemodynamic response during airway management and lower incidence of postoperative complications.
A review of applicant faking in selection interviews

Since faking is a common phenomenon in personnel selection (Donovan, Dwight, & Hurtz, 2003) there is a long history of research on faking in personality tests (e.g., Birkeland, Manson, Kisamore, Brannick, & Smith, 2006; Viswesvaran & Ones, 1999). Furthermore, the examination of impression management tactics that are used by job applicants in employment interviews is not new (e.g., Gilmore & Ferris, 1989; Stevens & Kristof, 1995). However, it is only in the last decade that we have observed a growing interest in the examination of applicant faking in employment interviews (Bourdage, Roulin, & Levashina, 2017). The long reluctance of prior research to investigate interview faking might seem surprising given its practical implications. Indeed, the vast majority of applicants use faking tactics in interviews but applicants also vary in the extent to which they engage in faking (e.g., Levashina & Campion, 2007). As such, faking can potentially change their rank order, impact who gets hired, and thus represent a possible threat to the criterion-related validity of interviews. The turnaround point concerning interview faking research is probably the publication of Levashina and Campion's (2006) theoretical model of applicant faking in interviews and of their subsequent scale to measure faking in interviews (Levashina & Campion, 2007). Over a decade later, we believe that enough theoretical and empirical work has been accumulated over recent years to warrant a first review. This review makes a number of important contributions to the literature. First, we identify issues for which sufficient data are available and consensus has been reached. Second, we identify relevant limitations of previous research as well as important but still unanswered questions for which more research is needed. Third, we discuss possible reasons for diverging findings in certain areas and describe the necessary research to gain insights into the reasons for these findings. Fourth, we provide suggestions for future theoretical Received: 21 August 2019 | Revised: 18 December 2019 | Accepted: 12 January 2020 DOI: 10.1111/ijsa.12280
Cardiovascular risk assessment in ecuadorian elderly population yield of four different models

Objectives The present study aims to: i) calculate the cardiovascular disease (CVD) risk profile of an Ecuadorian hypertensive elderly sample using four different models: (1) the 2003 Systematic Coronary Risk Evaluation (SCORE) risk model, (2) the 2008 Framingham Risk Score (FRS, both using lipids profile and body mass index - BMI), (3) the 2013 AHA/ACC Pooled Cohort Equations model, and (4) the 2015 SCORE for Older Population - O.P., and; ii) assess the relationship between several independent variables: (1) dependence; (2) abuse; (3) creatinine; (4) estimated glomerular filtration rate (eGFR); (5) glucose; (6) HOMA-IR index; (7) albumin; (8) thyroid stimulating hormone (TSH); (9) high-sensitivity C-reactive protein (hsCRP); and (10) vitamin D (25OHD) serum levels and predicted CVD risk in the elderly according to each of the four tested models. Methods This cross-sectional study analyzed the Ecuadorian National Dataset of Health, Welfare and Aging in the Elderly (SABE-ECU) conducted in 2009. From 5235 subjects belonged to the original database, a sample of 951 participants was selected after excluded missing values. We estimated the predicted 10-year risk of CVD based on the four model equations previously mentioned. In addition, logistic regression models were used to find odds ratios (OR) and corresponding 95% confidence intervals (CI) between proposed novel cardiovascular risk factors and predicted CVD risk. Results In 2009, one-third of the Ecuadorian hypertensive elderly population is allocated in the “high CVD risk” category according to the four equations used. In the adjusted logistic regression model, low eGFR (<60 ml/min, OR 0.23, [0.06-0.92]), low albumin serum level (<3.5 g/dl, OR 8.09, [1.63-40.04]), high HOMA-IR index (≥3.2, OR 2.01, [1.22-3.30]), and high hsCRP serum level (≥1.1 mg/L, OR 2.00, [1.12-3.58]) showed association with CVD risk when using FRS and SCORE O.P. models. Conclusion We found that low eGFR, high HOMA-IR index, low albumin and high hsCRP serum levels are independently and significantly associated with CVD risk in the study individuals. These laboratory variables could be included as predictor markers for CVD risk in future elder-validated scores. More studies are needed to assess the complex interaction between aging, hypertension, nutritional
Treating Obstructive Sleep Apnea with Continuous Positive Airway Pressure May Aid Weight Loss in Patients with Obesity on a Calorie Restriction Diet

Results: Total 300 patients were divided into asymptomatic patients (OSA-A, n = 89), symptomatic OSA (OSA-S, n = 164), and OSA on CPAP treatment (OSA-T, n = 47) groups. At the end of 16 weeks, the absolute weight loss of the OSA-T group was significantly greater than that of the OSA-S and OSA-A groups (-12.1 ± 5.9 vs. -9.5 ± 5.5 vs. -8.7 ± 5.3 kg, P < 0.01). A correlation of CPAP treatment to the absolute weight loss (Spearman’s correlation coefficient -0.181, P = 0.013) was established after adjustment of body weight, age and gender.
EQUILIBRIUM VALUATION OF CURRENCY OPTIONS UNDER A DISCONTINUOUS MODEL WITH CO-JUMPS

Abstract In this paper, we study the equilibrium valuation for currency options in a setting of the two-country Lucas-type economy. Different from the continuous model in Bakshi and Chen [1], we propose a discontinuous model with jump processes. Empirical findings reveal that the jump components in each country's money supply can be decomposed into the simultaneous co-jump component and the country-specific jump component. Each of the jump components is modeled with a Poisson process whose jump intensity follows a mean reversion stochastic process. By solving a partial integro-differential equation (PIDE), we get a closed-form solution to the PIDE for a European call currency option. The numerical results show that the derived option pricing formula is efficient for practical use. Importantly, we find that the co-jump has a significant impact on option price and implied volatility.
Bacterial Community Composition of Sapanca Lake During a Cyanobacterial Bloom

Microbial community compositions and functions of freshwater ecosystems vary due to the environmental parameters and water chemistry. Transient bloom events play a crucial role on the community profiles. In this study, a specific focus was set to provide a snapshot of the bacterial community composition in Lake Sapanca, associated with cyanobacterial bloom by high throughput sequencing method. For this purpose, a sample was collected in the shore of Lake Sapanca during a cyanobacterial bloom, and the bacterial community profile was examined by 16S rRNA amplicon sequencing using the Illumina MiSeq platform. Cyanobacteria represented 94% of the all reads. The bacterial community was re-calculated to evaluate the bacterial diversity in detail by filtering cyanobacterial sequences. The community was dominated by Proteobacteria (44%) and Bacteroidetes (33%) species which are abundant in freshwater ecosystems having an ability to degrade complex organics. Among the classified genera, Flavobacterium and Rheinheimera dominated the bacterial community suggesting a strong link between those species and the cyanobacterial bloom. The experimental work presented here provides one of the first investigations of total bacterial communities in Lake Sapanca by the high throughput sequencing method. Further work is needed with more sampling points and time series to fully understand the bacterial diversity and dynamics.
Comparison of Right- and Left-Leg Balance Points in Female Volleyball Players and Sedentary Controls

Abstract This research was conducted to compare the static and dynamic balance points of sedentary women and volleyball players. 10 athletes and 11 sedentary women participated in this research. Balance measurements were done by FBT (Flamingo Balance Test) for static balance and SEBT (Star Excursion Balance Test) for dynamic balance. Sedentary group’s total dynamic balance value was measured as 619.1± 48.99, and athlete group’s was 704.88±67.80. Static balance value of sedentary group was 17.46± 3.05, and athlete group’s was 10.75±4.71. As a result, in the both dynamic and static balance values, athlete group had significantly better balance points than the others. It can be stated that this is a result of long term regular training of the athlete group. Also, the left-foot dynamic balance points were higher compared to the right-foot dynamic balance points in especially athletes. The results suggest that leg balances may be related to cerebral lateralization.
Ergodic capacity of antenna selection aided massive multi-user MIMO systems with imperfect CSI in correlated time-varying channels

In this study, the authors address antenna selection (AS)-aided massive multi-user multiple-input-multiple-output (MU-MIMO) system based on maximum signal-to-noise ratio, where imperfect channel state information (CSI), time-varying channel and antenna spatial correlation are considered. More explicitly, a computationally simple training-based channel estimator is firstly employed for obtaining the imperfect down-link CSI. Channel quantisation (CQ) is subsequently introduced by the feedback link which is used for feeding back so-obtained CSI to base station. Time varying coefficient is utilised to characterise channel time variety and antenna spatial correlation is modelled by Kronecker model. Furthermore, the authors derive closed-form ergodic channel capacity of the AS-aided MU-MIMO system with channel estimation error, CQ error and delay feedback, which has not yet been addressed in the state-of-the-art approaches. Simulation results are provided to demonstrate the tightness of their theoretical computations of the ergodic channel capacity.
Clinical Study of Coma in Children

1 Associate Professor, Department of Paediatrics, Govt. Vellore Medical College, Vellore 2 Assistant Professor, Department of Paediatrics, Govt. Vellore Medical College, Vellore 3 Professor, Department of Paediatrics, Govt. Vellore Medical College, Vellore *Corresponding Author Dr Theranirajan E Professor of Paediatrics, Department of Paediatrics, Govt. Vellore Medical College, Vellore Ph: 9003517417, Email: theranirajan1966@gmail.com ABSTRACT Background: Coma is a state of unarousable psychogenic unresponsiveness, in which the subjects lie with eyes closed. It has been an enigma for clinicians for many years and searching for the cause and prognosis is always a huge task. Objective: To study the etiology of coma, find out morbidity and mortality pattern and to determine the outcome of coma in children. Method: 60 children in the age group of 2 months to 12 years for a period of one year from January 2016 to December 2016, admitted with non-traumatic coma in the Department of Paediatrics, Govt, Vellore Medical College, Vellore were included in the study. A detailed history was taken and thorough examination was done according to the proforma. Patients were evaluated daily till discharge as advised or death. Outcome was classified into good recovery, moderate disability, severe disability, persistent vegetative state and death. Results: The incidence of non-traumatic coma was 1.18% among all paediatric admissions. The common cause of non-traumatic coma in the present study was due to Metabolic-Toxic lesions (81.66%) as compared to structural lesions (18.34%). Mortality due to structural causes was high (18.18%) when compared to metabolic-toxic lesions. Low GCS, abnormal pupillary reflex, absent corneal reflex and Doll’s eye movement had significant impact on prognosis. Children with coma duration more than 48 hours had 22.22% mortality (p value 0.02). Conclusion: CNS infections are the commonest cause of non-traumatic coma and it is possible to predict mortality and morbidity due to non-traumatic coma with simple clinical signs.
Productive Performances of Crossbred Dairy Cattle at Holetta Agricultural Research Center

This study was conducted to evaluate the productive performances of crossbred dairy cattle at Holetta research center dairy farm. A total of 6685 performance records were used and analyzed to determine the effect of period of calving, season of calving, parity and genetic group. The parameters used us indicator of productive performances were Lactation milk yield (LMY), daily milk yield (DMY) and lactation length (LL). The GLM procedure of SAS 2004 software was used for analysis. The overall least square means and standard errors for Lactation milk yield (LMY), daily milk yield (DMY) and lactation length (LL) were ÷ 2204.05 ± 21.12 kg, 6.88 ± 0.05 kg and 326.69 ± 2.03 days, respectively. Result of fixed effect analysis indicated that calving period, genetic group and parity were significantly (p 50%) in the present study revealed that performances were continued to increase with increasing proportion of exotic genes. Keywords: Borena, Ethiopia, Holetta, Holstein Friesian DOI : 10.7176/FSQM/92-04 Publication date: December 31 st 2019
Prospective randomized comparative study of skin adhesive glue (2- methyl -2- cyanopropionate or cyanoacrylate) versus conventional skin suturing by suture material/skin stapler in clean surgical cases

Background: To compare cosmetic appearance of skin closure wound by three methods -sutures, staples and skin adhesive glue. Traditional skin closure using sutures causes more pain, infection, needs its removal, time consuming and leaves behind bad scar. Nowadays, good cosmetic appearance of operated site is appealing among patients. Surgeons are looking for faster, comfortable and cosmetically best technique for skin closure. Newer techniques need to be evaluated which are better than suture and staples. 2-octylcyanoacrylate is easier to use, flexible, water resistant, pain free sealed skin closure without its need for removal and has better cosmesis. Methods: This study is conducted from July 2010 to April 2013 in 90 patients at LTMG Hospital. Wounds of clean surgeries closed with suture material, skin staples and skin adhesive glue were studied in 30 patients each. Patients were randomized using standardized methods. Patients followed up over period of 28 days and their scars were assessed according to the modified Hollander cosmesis scale(MHCS) and cosmetic visual analogue scale(VAS). Patient allotment was done using random number table. Results: Mean MHCS score for skin adhesive group on day 7 was 4.83 which was significantly more than 3.90for suture and 3.97 for stapler. Mean VAS score for skin adhesive group on day 7 was 67.67 which was significantly more than 61.67 for suture and stapler each. Mean MHCS and VAS score for skin adhesive group on day 7, 14 and 28 were significantly more than suture and stapler groups. Conclusions: Octylcyanoacrylate can be used for skin closure in clean elective surgeries with better cosmetic outcome as compared to staples and sutures.
Progress in the second-moment closure for bubbly flow based on direct numerical simulation data

Data from direct numerical simulations (DNS) of disperse bubbly flow in an upward vertical channel are used to develop a new second-moment closure for bubble-induced turbulence (BIT) in the Euler–Euler framework. The closure is an extension of a BIT model originally proposed by Ma et al. (Phys. Rev. Fluids, vol. 2, 2017, 034301) for two-equation eddy-viscosity models and focuses on the core region of the channel, where the interfacial term and dissipation term are in balance. Particular attention in this study is given to the treatment of the pressure–strain term for bubbly flows and the form of the interfacial term to account for BIT. For the latter, the concept of an effective BIT source is proposed, which leads to a significant simplification of the modelling work for both the pressure–strain correlation and the interfacial term itself. The anisotropy of bubbly flow is analysed with the aid of the anisotropy-invariant map obtained from the DNS data, and a parameter governing this issue is established. The complete second-moment closure is tested against reference data for different bubbly channel flows and a case of a bubble column. The agreement achieved with the DNS data is very good and the performance of the new model is better than obtained with the standard procedure. Furthermore, the model is shown to be robust and to fulfil the requirements of realizability.
Residualization: justification, properties and application

Although it is usual to find collinearity in econometric models, it is commonly disregarded. An extended solution is to eliminate the variable causing the problem but, in some cases, this decision can affect the goal of the research. Alternatively, residualization not only allows mitigation of collinearity, but it also provides an alternative interpretation of the coefficients isolating the effect of the residualized variable. This paper fully develops the residualization procedure and justifies its application not only for dealing with multicollinearity but also for separating the individual effects of the regressor variables. This contribution is illustrated by two econometric models with financial and ecological data, although it can also be extended to many different fields.