Miracle-dz/UniFAR-FTUs huggingface dataset:
Trajectories of Instrumental and Emotional Social Support and the Associated Risk of Mortality in Bereaved Older Adults in Taiwan

This study identified the trajectories of instrumental and emotional perceived social support (PSS) from 1996 to 2003 and investigated the associated risk of mortality in bereaved older adults in Taiwan. The study analyzed 1,188 bereaved older adults who had experienced loss of a spouse, a child, or both before 1996 from the Taiwan Longitudinal Study on Aging. More favorable trajectories of PSS are associated with lower mortality risk in bereaved older adults. Compared with the spousal or dual bereavement, the parental bereavement benefited more from consistently high instrumental PSS. The present study revealed that consistently high emotional PSS had a stronger protective effect on mortality risk for a widow or widower than did consistently high instrumental support. The findings of this study can serve as an empirical reference to inform social policies and clinical practices for bereaved older adults in culturally similar societies.
Mean free path of hot electrons at the surface of boron‐doped silicon

Electrons can be injected from silicon into silicon dioxide in a metal‐oxide‐semiconductor‐transistor (MOST) structure in which electrons are accelerated in the depletion layer of the channel region in a direction perpendicular to the Si‐SiO2 interface. An analysis of the resulting oxide current as a function of the reverse voltage applied to the source and drain regions is carried out using an extension of a model proposed by Shockley. This leads to an estimate of the mean free path λ of the hot electrons in the silicon. It appears that a heavily doped source and drain, formed by a phosphorus diffusion, or the dislocations generated by this diffusion, have the effect of increasing λ by, presumably, the removal of scattering centers. The largest value of λ observed, λ=135 A, is possibly equal to the value of the mean free path for the generation of high‐energy phonons.
Convenient Synthesis of N-Heterocycle-Fused Tetrahydro-1,4-diazepinones

A general approach towards the synthesis of tetrahydro-4H-pyrazolo[1,5-a][1,4]diazepin-4-one, tetrahydro[1,4]diazepino[1,2-a]indol-1-one and tetrahydro-1H-benzo[4,5]imidazo[1,2-a][1,4]diazepin-1-one derivatives was introduced. A regioselective strategy was developed for synthesizing ethyl 1-(oxiran-2-ylmethyl)-1H-pyrazole-5-carboxylates from easily accessible 3(5)-aryl- or methyl-1H-pyrazole-5(3)-carboxylates. Obtained intermediates were further treated with amines resulting in oxirane ring-opening and direct cyclisation—yielding target pyrazolo[1,5-a][1,4]diazepin-4-ones. A straightforward two-step synthetic approach was applied to expand the current study and successfully functionalize ethyl 1H-indole- and ethyl 1H-benzo[d]imidazole-2-carboxylates. The structures of fused heterocyclic compounds were confirmed by 1H, 13C, and 15N-NMR spectroscopy and HRMS investigation.
Adaptive time-delay estimation and control of optimized Stewart robot

Aiming at a more efficient and accurate performance of parallel manipulators in the existence of complex kinematics and dynamics, a robust generalizable methodology is proposed here for an integrated 6-DOF Stewart platform with rotary time-delayed actuators torque control. The suggested method employs a time-delay linear–quadratic integral regulator with online artificial neural network gain adjustment. The unknown time-delay is estimated through a novel robust adaptive estimator. The global asymptotic stability of the estimator is proved via a Lyapunov function. The controller is developed in MATLAB software and implemented on the robot designed in ADAMS software to ensure that the real-time tracking error of a nonlinear system with an unknown time-delay is kept to a minimum. The sensitivity of the controller to the parameter choices is studied via implementing the controller in ADAMS software and is validated by investigating the performance on a naturalistic fabricated robot. The approach is assessed using simulation and experimental tests to show the feasibility, optimum, and zero-error convergence of the technique developed.
An ultrasonography-based contrast-enhanced for distinguishing between benign and malignant hepatocellular carcinoma

To analyze the practical value of contrast-enhanced ultrasound in liver benign and malignant tumors. 60 patients with liver tumors were chosen as research materials from June 2019 to October 2021, and their malignant and benign tumors were analyzed by contrast-enhanced ultrasound. Results show ultrasonic imaging was used to test the sensitivity of liver malignant tumor, coincidence rate 92.7% to 92.9%, and index of 78 were significantly higher than that of conventional ultrasound (χ2 = 8.8000, 9.9068, 9.3544, p<0.01). The initial increase time (18.25±3.04), peak time (35.73±8.43), decreased time (55.42±0.89), and continuous enhancement time (84.96±1.57) for benign liver tumors were all higher than those for malignant tumors (t = 5.3487, 5.4924, 37.0273, 82.0934, p <0.01). The peak intensity of contrast enhanced ultrasound for benign tumors (19.57±3.43) was lower than that for malignant tumors (t = 4.3096, p<0.01). So, contrast-enhanced ultrasound has significant value in differentiating benign from malignant liver tumors.
Intrathecal Nalbuphine and Dexmedetomidine as Adjuvants to Bupivacaine versus Plain Bupivacaine for Orthopedic Surgeries under Subarachnoid Block: A Comparative Study

Background: In long bone surgeries, the severity of pain is more, demanding good intraoperative anesthesia, and prolonged postoperative analgesia. This is achieved in spinal anesthesia with adjuvants to local anesthetics, which act synergistically. Aims: The aim of this study was to compare the efficacy of nalbuphine and dexmedetomidine as adjuvants to bupivacaine versus bupivacaine alone in lower limb orthopedic surgeries under the subarachnoid block (SAB). Settings and Design: This is a prospective, randomized, double-blind control study conducted on 60 patients belonging to the American Society of Anesthesiologists physical status Classes I and II, undergoing lower limb orthopedic surgeries under SAB. Materials and Methods: Sixty patients were divided into three groups by computer-generated randomization. Group A received 2.7 mL of 0.5% hyperbaric bupivacaine with 1.5 mg nalbuphine, Group B received 2.7 mL of 0.5% hyperbaric bupivacaine with 10 μg dexmedetomidine, and Group C received 2.7 mL of 0.5% hyperbaric bupivacaine with 0.5 mL of normal saline (total volume made to 3.2 mL in all groups with normal saline). Time of onset of block, duration of sensory, and motor blocks were noted. Changes in hemodynamic parameters, postoperative first rescue analgesia requirement, and side effects were recorded. Statistical Analysis Used: Data were analyzed using SPSS 22 version software. P < 0.05 was considered statistically significant. Results: There was no significant difference in the onset of sensory or motor blocks in the three groups. However, the time taken for regression of sensory block was longer in Group B that was statistically significant. Conclusion: Intrathecal dexmedetomidine acts as a better adjuvant with bupivacaine in providing quality anesthesia, prolonged sensory and motor block, and good postoperative analgesia with less incidence of adverse effects compared to nalbuphine and bupivacaine alone.
Environmental niche overlap in sibling planktonic species Calanus finmarchicus and C. glacialis in Arctic fjords

Abstract Knowledge of environmental preferences of the key planktonic species, such as Calanus copepods in the Arctic, is crucial to understand ecosystem function and its future under climate change. Here, we assessed the environmental conditions influencing the development stages of Atlantic Calanus finmarchicus and Arctic Calanus glacialis, and we quantified the extent to which their niches overlap by incorporating multiple environmental data. We based our analysis on a 3‐year seasonal collection of zooplankton by sediment traps, located on moorings in two contrasting Svalbard fjords: the Arctic Rijpfjorden and the Atlantic‐influenced Kongsfjorden. Despite large differences in water temperature between the fjords, local realized ecological niches of the sibling Calanus species overlapped almost perfectly. The exception was the earliest copepodites of C. glacialis in Rijpfjorden, which probably utilized the local ice algal bloom in spring. However, during periods with no sea ice, like in Kongsfjorden, the siblings of both Calanus species showed high synchronization in the population structure. Interestingly, differences in temperature preferences of C. finmarchicus and C. glacialis were much higher between the studied fjords than between the species. Our analysis confirmed the high plasticity of Calanus copepods and their abilities to adapt to highly variable environmental settings, not only on an interannual basis but also in a climate warming context, indicating some resilience in the Calanus community.
Performance of Derived Laboratory Biomarkers with Regard to 30-Day Mortality in Kidney Transplant Recipients with COVID-19

There are limited data on the performance of laboratory-derived biomarkers in kidney transplant recipients (KTR) with COVID-19. This observational study enrolled 65 KTR with COVID-19 who were treated at the University Hospital of Split up to March 2022. Laboratory-derived biomarkers (neutrophile-to-lymphocyte (NLR) ratio, platelet-to-lymphocyte ratio, monocyte-to-lymphocyte ratio, De Ritis ratio, C-reactive protein (CRP)-to-albumin ratio, lactate dehydrogenase (LDH)-to-hemoglobin ratio, CRP-to-lymphocyte ratio, red cell distribution width-to-albumin ratio, platelet-to-albumin ratio, D-Dimer-to-albumin ratio, D-Dimer-to-NLR ratio, LDH-to-albumin ratio, and LDH-to-white blood cell (WBC) ratio) were calculated, and their performance with regard to 30-day mortality was determined. Mortality events occurred in 12 patients (18.5%), which was significantly associated with increased De Ritis (HR 3.83, 95% CI 1.57–9.35, p = 0.003), CRP-to-albumin (HR 1.36, 95% CI 1.13–1.64, p = 0.001), LDH-to-hemoglobin (HR 1.44, 95% CI 1.07–1.92, p = 0.015), CRP-to-lymphocyte (HR 1.03, 95% CI 1.01–1.07, p = 0.003), D-dimer-to-albumin (HR 4.94, 95% CI 1.38–7.24, p = 0.038), LDH-to-albumin (HR 1.20, 95% CI 1.05–1.36, p = 0.008), and LDH-to-WBC (HR 1.03 95% CI 1.01–1.05, p = 0.024) ratios. Out of these, the best area-under-the-curve (AUC) values were achieved with De Ritis (AUC 0.691), CRP-to-albumin (AUC 0.764), LDH-to-hemoglobin (AUC 0.877), CRP-to-lymphocyte (AUC 0.739), and LDH-to-albumin (AUC 0.827) ratios, while the best discrimination displayed LDH-to-hemoglobin ratio (Harrell’s C 0.808 and Somers’ D 0.616). The overall calibration was satisfactory for all models. Derived laboratory biomarkers such as the de Ritis, CRP-to-albumin, LDH-to-hemoglobin, CRP-to-lymphocyte, and LDH-to-albumin ratios show significant association and discrimination with all-cause mortality in KTR with COVID-19, suggesting its potential risk stratification role.
Interstellar 12C/13C ratio revisited

Observations of the molecular ion CH + at 4232 A in the direction of ζ Oph have determined the 12 CH + / 13 CH + abundance ratio to be 67.6±4.5. The equivalent widths of 12 CH + and 13 CH + lines used for this determination were 23.246±0.068 mA and 0.410±0.022 mA, respectively. The line profiles show a very broad component with Gaussian velocity dispersion parameter b=9.9±1.3 km s −1 . These data provide strong evidence that the 12 C/ 13 C abundance ratio in the direction of ζ Oph is close to 70
Generation of Multiple Arbovirus-like Particles Using a Rapid Recombinant Vaccinia Virus Expression Platform

As demonstrated by the 2015 Zika virus outbreak in the Americas, emerging and re-emerging arboviruses are public health threats that warrant research investment for the development of effective prophylactics and therapeutics. Many arboviral diseases are underreported, neglected, or of low prevalence, yet they all have the potential to cause outbreaks of local and international concern. Here, we show the production of virus-like particles (VLPs) using a rapid and efficient recombinant vaccinia virus (VACV) expression system for five tick- and mosquito-borne arboviruses: Powassan virus (POWV), Heartland virus (HRTV), severe fever with thrombocytopenia syndrome virus (SFTSV), Bourbon virus (BRBV) and Mayaro virus (MAYV). We detected the expression of arbovirus genes of interest by Western blot and observed the expression of VLPs that resemble native virions under transmission electron microscopy. We were also able to improve the secretion of POWV VLPs by modifying the signal sequence within the capsid gene. This study describes the use of a rapid VACV platform for the production and purification of arbovirus VLPs that can be used as subunit or vectored vaccines, and provides insights into the selection of arbovirus genes for VLP formation and genetic modifications to improve VLP secretion and yield.
On The Properties Of Random Entire Functions

We consider random entire functions of the form where (X j (ω), j≥0) is a sequence of independent and identically distributed random variables defined on the probability space (Ω, A, P), ω∈Ω and z=re iθ . An important characteristic of f(z, ω), is sup θ∈[−π,π]| f(re iθ ,ω)|, with its growth as r→∞ of particular significance. Results describing the latter using the Wiman–Valiron method are known for random entire functions generated by bounded random variables. In contrast to this work, we consider the important class of Gaussian entire functions and determine the properties of sup θ∈I ε | f(re iθ ,ω)| for large r, when I ε⊂[−π,π] excludes a neighbourhood of θ=0. As our techniques exploit the assumption that f(re iθ ,ω),θ∈[−π,π] is a Gaussian process, we show that a wide range of random entire functions have Gaussian characteristics for sufficiently large r. The latter may be of independent interest as it can be used to determine the expected number of zero crossings of the real and imaginary parts of f(re iθ ,ω) and related quantities. #This work was carried out as part of Technology Group 10 of the MoD Corporate Research Programme. (©British Crown Copyright 2000/DERA.)
EXISTENCE OF SOLUTIONS OF STRONG VECTOR EQUILIBRIUM PROBLEMS

In this paper, we consider strong form of a vector equilibrium problem and establish some existence results for solutions of such a problem in the setting of topological vector spaces. We provide several coercivity conditions under which strong vector equilibrium problem has a solution. Our results generalize and extend the results of Bianchi and Pini [10] to the topological vector space setting.
The II P method for estimating multivariate functions from noisy data

The Π method for estimating an underlying smooth function of M variables, (x l , …, xm ), using noisy data is based on approximating it by a sum of products of the form Π m φ m (x m ). The problem is then reduced to estimating the univariate functions in the products. A convergent algorithm is described. The method keeps tight control on the degrees of freedom used in the fit. Many examples are given. The quality of fit given by the Π method is excellent. Usually, only a few products are enough to fit even fairly complicated functions. The coding into products of univariate functions allows a relatively understandable interpretation of the multivariate fit.
A multivariate analysis of undergraduate physics students' conceptions of quantum phenomena

Both pre-university and undergraduate students have conceptual problems with the ideas in quantum physics. The initial findings of a study to investigate undergraduate students' understanding of quantum phenomena are presented. The study shows that a questionnaire approach can be used to elicit students' ideas regarding quantum phenomena and that multivariate analysis can be used to draw out both clusters of conceptions and dimensions of understanding.
Quantitative studies of spin-momentum-transfer-induced excitations in Co/Cu multilayer films using point-contact spectroscopy

We have measured current-induced magnetic excitations in a variety of exchange-coupled Co/Cu multilayers using point-contact spectroscopy. A step in the dc resistance and corresponding peak in dV/dI are observed at a critical current Ic whose value depends linearly on applied magnetic field Bapp′ in agreement with Slonczewski’s theory. These features are observed for both in- and out-of-plane fields. Excitations in ferromagnetically coupled films occur even without an applied field. The spin transfer efficiency is determined from the slope and intercept of Ic vs Bapp and varied from contact to contact. For out of plane magnetized samples, the deduced spin transfer efficiency values are in good agreement with the predictions of Slonczewski.
Perils of Underestimating Species Diversity: Revisiting Systematics of Psammocambeva Catfishes (Siluriformes: Trichomycteridae) from the Rio Paraíba do Sul Basin, South-Eastern Brazil †

Psammocambeva, a subgenus of Trichomycterus s.s. , includes a clade endemic to south-eastern Brazil, the Psammocambeva alpha-clade (PAC), containing species with similar colour pattern and fin morphology, making difficult their identification without accurate examination. The greatest diversity of PAC species occurs in the Rio Paraíba do Sul basin area (RPSA), situated within the Atlantic Forest, one of the most important and endangered biodiversity centres in the world. Herein, we: perform a multigene phylogeny focusing on species of PAC; revise morphological characters diagnosing species of PAC from the RPSA, with special attention to those equivocally synonymised in a recent study; describe two new species, and provide a key for species identification. Molecular and morphological evidence supported the recognition of eight valid species belonging to four species complexes. Data indicated that T. auroguttatus, T. travassosi, and T. longibarbatus are valid species. Finally, we discuss the negative impacts of underestimating species diversity in regions under the intense process of natural habitat loss, concluding that integrative approaches are important tools to estimate species diversity, but they should include a range of morphological characters informative to delineate and diagnose groups and their respective species, in association with phylogenies generated by robust molecular datasets.
Modeling differential car-following behavior under normal and rainy conditions: A memory-based deep learning method with attention mechanism

In order to analyze and learn the difference in car-following behavior between normal and rainy days, we first collect car-following trajectory data of an urban elevated road on normal and rainy days by microwave radar and analyze the differences in speed, relative speed, acceleration, space headway, and time headway among data through statistics. Secondly, owing to the time-series characteristics of car-following data, we use the long short-term memory (LSTM) neural network optimized by attention mechanism (AM) and sparrow search algorithm (SSA) to learn the different car-following behaviors under different weather conditions and build corresponding models (ASL-Normal, ASL-Rain, where ASL stands for AM-SSA-LSTM), respectively. Finally, the simulation test shows that the mean square error (MSE) and reciprocal of time-to-collision (RTTC) of the ASL model are better than those of LSTM and intelligent diver model (IDM), which is closer to the real data. The ASL model can better learn different driving behaviors on normal and rainy days. However, it has a higher sensitivity to weather conditions from cross test on normal and rainy data-sets which need classification training or sample diversification processing. In the car-following platoon simulation, the stability performances of two models are excellent, which can describe the basic characteristics of traffic flow on normal and rainy days. Comparing with ASL-Rain model, the convergence time of ASL-Normal is shorter, reflecting that cautious driving behavior on rainy days will reduce traffic efficiency to a certain extent. However, ASL-Normal model produces a more severe and frequent traffic oscillation within a shorter period because of aggressive driving behavior on normal days.
A logistics scheduling model: scheduling and transshipment for two processing centers

Logistics scheduling refers to problems in which decisions on job scheduling and transportation are integrated into a single framework. A logistics scheduling model for two processing centers that are located in different cities is presented. Each processing center has its own customers. When the demand in one processing center exceeds its processing capacity, it is possible to use part of the capacity of the other processing center subject to a job transshipment delay. Such a coordinated scheduling situation can be modeled as a parallel-machine scheduling problem with transshipment between the machines. We study problems with different objective functions and constraints, and propose various algorithms to solve these problems. Discussions on the benefits and incentives for the coordinated approach are presented.
Transjugular Intrahepatic Portosystemic Shunt in Chronic Portal Vein Thrombosis—From Routine Recommendations to Demanding Scenarios

Portal vein thrombosis (PVT), particularly the presence of portal cavernoma, was traditionally considered a relative contraindication for transjugular intrahepatic portosystemic shunting (TIPS) due to the technical difficulties in accessing and maneuvering the portal vein and avoiding the high risk for bleeding periportal collaterals. However, the last decade has seen a surge in the number of studies—mostly case reports and small series of patients—demonstrating that TIPS is not only technically feasible in the vast majority of these patients but also provides effective and long-term control of symptoms associated with portal hypertension in cases refractory to the standard line of therapy. The present article aims to provide a concise but exhaustive overview of the role and the standard and technically difficult TIPS placement scenarios in patients with chronic non-malignant PVT and with and without underlying liver disease. The review is strategically punctuated by exemplary instances from the authors’ experience.
The distribution of bright OB stars in the Canis Major–Puppis–Vela region of the Milky Way

The picture of the young stellar groups in the Canis Major–Puppis–Vela (215°<l<275°) section of the Milky Way is studied and updated utilizing uvbyβ photometry of intrinsically luminous OB stars. We use all data from the literature to create a sample with 98 per cent completeness to 9.5 mag. The very dense low reddened OB association CMa OB1 is confirmed at a distance of 0.99 (±0.05 s.e.) kpc. Towards Puppis the brightest intrinsically luminous stars do not reveal Pup OB1 and Pup OB2. In the same direction, we separate two small groups, previously related to the association surrounding NGC 2439 at 3.5–4.5 kpc. The first one contains four highly reddened B-type supergiants situated in front of the cluster at 1.03 (±0.14 s.e.) kpc – much closer to the Sun than has been estimated before. The second one lies north-west from the cluster at 3.2 (±0.23 s.e.) kpc according to our estimate. In the direction to Vela, the bright OB stars are apparently embedded in a dust cloud and spread out between 0.3 and 2.5 kpc, forming clumps over this distance range. In general, the prominent apparent young structures delineated by the brightest intrinsically luminous OB stars in the directions of Canis Major and Vela are some 20–25 per cent closer to the Sun than has previously been thought. This is in agreement with the Hipparcos results for the Galactic OB associations, and is highly likely to be caused by the overestimation of the spectroscopic distances used in the previous studies.