Miracle-dz/UniFAR-FTUs huggingface dataset:
A Network Pharmacology Approach to Reveal the Underlying Mechanisms of Paeonia lactiflora Pall. On the Treatment of Alzheimer's Disease

Objective To investigate the potential active compounds and underlying mechanisms of Paeonia lactiflora Pall. (PLP) on the treatment of Alzheimer's disease (AD) based on network pharmacology. Methods The active components of PLP were collected from Traditional Chinese Medicine System Pharmacology (TCMSP) database, and their possible target proteins were predicted using TCMSP, SwissTargetPrediction, and STITCH databases. The putative AD-related target proteins were identified from Therapeutic Target Database (TTD), GeneCards, and MalaCards database. The compound-target-disease network interactions were established to obtain the key targets about PLP acting on AD by network topology analysis. Then, the function annotation and signaling pathways of key targets were performed by GO and KEGG enrichment analysis using DAVID tools. Finally, the binding capacity between active ingredients and key targets was validated by molecular docking using SystemsDock tools. Results There were 7 active compounds involving in 151 predicted targets identified in PLP. Besides, a total of 160 AD-related targets were identified. Among these targets, 30 shared targets of PLP and AD were acquired. After topological analysis of the PLP potential target-AD target network, 33 key targets that were highly responsible for the therapeutic effects of PLP on AD were obtained. Further GO and KEGG enrichment analysis showed that these key targets were significantly involved in multiple biological processes and pathways which participated in cell apoptosis and inflammatory response and maintained the function of neurons to accomplish the anti-AD activity. The molecular docking analysis verified that the 7 active compounds had definite affinity with the key targets. Conclusions The ameliorative effects of PLP on AD were predicted to be associated with regulating neural cell apoptosis, inflammatory response, and neurotrophy via various pathways such as PI3K-Akt signaling pathway, MAPK signaling pathway, and neurotrophin signaling pathway.
E-learning Benchmarking Adoption: A Case Study of Sur University College

As an integral tool nowadays, e-learning presents fresh paradigm in the fields of education and management. The effectiveness of e-learning in the improvement of learning and teaching method has been proven. Accordingly, there have been countless works carried out to gain comprehension on the adoption of e-learning particularly in terms of its use extent. Furthermore, a new model of e-learning Success based on McLean & DeLone Information System Success (IS Success) and Diffusion of Innovation (DOI) and the effects of e-learning on student’s performance are comprehensively highlighted. Appositely, e-learning benchmarking adoption among students is characterized and measured in this study with the integration of DOI with IS Success attributed with such adoption. In this quantitative study, data were gathered from the students enrolled in SUC. The results indicate that and the variables of relative advantage, complexity, system quality, information quality and service quality appear to have significant linkage to the adoption of e-learning as well as net benefit is significantly correlated with the adoption of e-learning. In regards to the used methods for examining the adoption of e-learning particularly, future studies could benefit from the use of quantitative and qualitative methods in combination.
Effect of Withania somnifera in the treatment of male infertility: A literature review

The high prevalence of male infertility associated with the high costs of its conventional treatment motivated researchers to look for alternative approaches to the treatment of sexual dysfunction. The use of medicinal plants for these fins has been adopted in Withania somnifera which is one of the plants that has been associated with improvements in male fertility. Thus, the aim of this study was to review data available in the literature on the effect of W. somnifera in the treatment of male infertility. The Pubmed, Lilacs and Medline databases from 2009 to 2019 were searched and 9 articles selected, including intervention articles, systematic review and meta-analysis. Also known as Aswagandha or "Indian Ginseng", the part of W. somnifera most used in treating infertility is the root, mainly in the form of extract. It acts through two mechanisms: "oxidative" and "non-oxidative", both associated with improved sperm count, motility and morphology. However, further studies should be conducted investigating isolated phytochemicals to verify their true functionality. Key words: Male infertility, male sexual disorders, Withania somnifera.
Perfective Aspect in the Languages of Madang Province, Papua New Guinea

When we consider tense and aspect in the grammars of the languages in the world, the perfective aspect and the related usages (completive, terminative, and imperfective) are important features (Bybee et al. 1994: chapter 3). This study examines perfective usages of Trans-New Guinea languages and Austronesian languages spoken in Madang Province, Papua New Guinea.1) Though Trans-New Guinea languages and Austronesian languages are grammatically and lexically different from each other (Foley 2000), this study tries to find common aspectual features by contrasting these sample languages (Lynch 1998: 62-64, Nose 2016a, Nose 2016b). This study chose the four sample languages spoken in Madang Province at the north-west of Papua New Guinea: Amele and Kobon in Trans-New Guinea, and Bel and Manam in Austronesian (see Figure 1). These languages might have connected Trans-New Guinea and Austronesian languages and their grammars could have influences each other (cf. Dempwolff n.d., Nose 2016b, Ross 2002). As a result, these languages generally maintain partly complicated elements in their grammars (Foley 2000). Moreover, they have dense contacts with Tok Pisin, the lingua franca of Papua New Guinea. This study examines the perfective features of the sample languages and summarizes them in terms of functional perspective. Finally, this study works to clarify aspectual features in the area and explain their perfective usages in terms of their semantic characteristics (Frawley 2013, Nose 2019). Perfective Aspect in the Languages of Madang Province, Papua New Guinea
LOCAL NGOS AND FOREIGN DONORS RELATIONSHIP IN THE CONTEXT OF PEACE-BUILDING A qualitatite analysis of the frictional encounter local/global in peace-building practices in postindependence Kosovo

This Master Thesis investigates the current role of LNGOs in delivering and implementing peacebuilding projects in the context of post-independence Kosovo. Due to LNGOs financial dependency from foreign donors, their role in peace-building has been questioned and challenged. The aim is to examine to what extent LNGOs are implementing the process of peace-building from below with regard to the relationship LNGOs/foreign donors. Semi-structured interviews with members from LNGOs in Kosovo have been carried out in order to collect empirical evidence to analyze the above objective. The relationship LNGOs/foreign donors has been framed according to the theory of frictional encounters between local/global and its possible outcomes. The empirical evidences show interesting results from the encounter LNGOs and foreign donors in Kosovo, which prove the possibility for LNGOs to pursue local needs and priorities in peace-building practices despite their financial dependency from foreign donors. This Thesis aims to fill the existing gap in peace-building and conflict resolution field. List of Abbreviations NGO = Non-governmental organization LNGO = Local Non-governmental organization INGO = International Non-governmental organization UN = United Nations UNMIK = United Nations Interim Administration Mission in Kosovo OSCE = Organization for Security and Co-operation in Europe EULEX = European Union Rule of Law Mission ICO = International Civilian Office UNHCR = The United Nations High Commissioner for Refugees USAID = The United States Agency for International Development UNDP = United Nations Development Programme ODA = Official Development Assistance KCS = Kosovar Civil Society EUFOR = European Union Force
The Relative Importance Of Transformational Leadership And Contingent Reward On Satisfaction With Supervision In Nonprofit And For-profit Organizations

We study the relationships and intervening mechanism between leaders’ transformational and contingent reward behaviors and the raters’ satisfaction with their supervision in the context of nonprofit and for-profit management settings in the United States. The results show that regardless of the context, transformational leadership on the part of the manager relates positively to the raters’ satisfaction with supervision and that this relationship is stronger in nonprofit organizations. Our results also provide evidence for the differential impact of contingent reward in for-profit and nonprofit settings. In the for-profit context, the relationship between contingent reward and satisfaction with supervision is negative while in nonprofit organizations this relationship is positive. In both contexts, transformational leadership positively moderates the effect of contingent reward on employee satisfaction with supervision. Our findings contribute to an improved understanding of how managers’ different leadership styles affect satisfaction depending on the organizational context. Practical implications for managers in both nonprofit and for-profit settings are provided
EFFECT OF CHEMICAL AND ORGANIC FERTILIZER AND AGRICULTURAL DISTANCES ON GROWTH AND YIELD OF TWO LETTUCE (LACTUCA SATIVA L.) VARIETIES GROWN UNDER UNHEATED PLASTIC HOUSE

This experiment was conducted in an unheated plastic house in Horticulture and Landscape design Department, college of Agriculture and Forestry, Mosul University during the winter season of the year 2013-2014 to investigate the possibility of lettuce crop production under protected condition during the winter season, which cannot be grown in the field at this time in Mosul City. Two lettuce cultivars were used Binco and Paris Island, the seeds were planted in 5/9 and transplanted inside the unheated plastic house in 5/11 at two agricultural distances: 30 and 40 cm and plants were fertilized with two organic fertilizers: Pow hums and Humistar which were applied to the soil as a solution at a rate of 3 gm.l for the two organic fertilizers, the control treatment was fertilized with a chemical fertilizer at the recommended rates. An RCBD factorial experiment with 12 treatments (2 x 2 x 3) were used. Results showed that there were no significant differences between the two varieties in most vegetative growth and yield traits while there were a significant superiority of the 40 cm distance on the 30 cm distance in head circumference, leaf area, stem weight and mean marketable head weight while there were a significant superiority of the treatment of 30 cm planting distance in terms of marketable and total yield. It is worth to note that there were no significant differences between the organic fertilization treatments with the normal chemical fertilized plants in terms of vegetative and yield in all vegetative traits mentioned traits expect the mean stem weight.
CYTOGENETIC BIOMONITORING AND IMMUNOCYTOCHEMICAL STUDIES ON CAR SPRAY PAINTERS IN ENUGU METROPOLIS, ENUGU STATE, NIGERIA

Objective: This study assessed the cytogenetic damage associated with occupational exposure to paints by evaluating exfoliated buccal epithelial cells from car spray painters in Enugu metropolis using some biological markers. Methods: A total of 352 apparently healthy males, comprising 200 car spray painters and a control group of 152 individuals, participated in the study. Buccal smears were obtained from each participant and were stained using hematoxylin and eosin technique. A total of 1000 cells per individual were scored under light microscopy to determine the frequencies of micronuclei (MN) and binucleate cells (BNC). Structured questionnaires were used to obtain relevant participant information. Expression patterns of Ki-67and p53 genes on the buccal cells were determined by immunocytochemical methods. Results: Car spray painters had significantly increased frequencies of MN and BNC (*p<0.05) when compared to the control subjects. Paint sprayers aged over 35 years had higher buccal cell MN frequency when compared to those <25 years. Furthermore, car spray painters who have worked for ≥15 years had higher frequencies of MN when compared to those who had worked for <5 years (*p<0.05). Smoking and alcohol consumption increased the MN frequency of the car spray painters (*p<0.05). There was no expression of p53 and Ki-67 genes in the buccal cells of both control and exposed subjects. Conclusion: Car spray painters in Enugu metropolis may be occupationally exposed to substances capable of inducing genotoxic changes which manifested as increased frequency of MN in their buccal cells.
THE NATURE OF THE DRAUPNER GIANT WAVE OF 1 JANUARY 1995 AND THE ASSOCIATED SEA-STATE, AND HOW TO ESTIMATE DIRECTIONAL SPREADING FROM AN EULERIAN SURFACE ELEVATION TIME HISTORY

On New Year’s Day of 1995 a severe storm occurred in the central North Sea at Statoil’s Draupner platform. At just before 15.30, a wave crest of 18.5m was recorded by a downwards pointing laser wave gauge. This is one of the highest wave crests ever recorded in the North Sea and has generated much interest as a possible ‘freak’ or ‘rogue’ wave, see for example Haver and Jan Andersen (2000) and Prevosto and Bouffandeau (2002).
Acorpus-Basedresearai of Adjecfive+ Preposition Patterns Found in English as Second Language (ESL) Learners' Handout

This corpus-based research attempted to analyze whether the Adjective + preposition patterns taught in Structure 4 course were commonly used in the English native speakers’ real communication as reflected in a corpus. The primary data were taken from Structure 4 materials used by the Faculty of Language and Literature, Satya Wacana Christian University. Meanwhile, language samples gotten from Corpus of Contemporary American English (COCA) became the secondary data. The patterns of Adjective + Preposition were grouped into two classifications, the major and minor usages. The results of this research showed that materials of Structure 4 coursereflected the major usage of the English real communication. 51percent of Adjective + Preposition patterns written on the handout were used as the major usage in the realcommunication of English native speakers. Meanwhile, the 49 percent reflected the minor usage
Cross-Lingual Ability of Multilingual BERT: An Empirical Study

Recent work has exhibited the surprising cross-lingual abilities of multilingual BERT (M-BERT) -- surprising since it is trained without any cross-lingual objective and with no aligned data. In this work, we provide a comprehensive study of the contribution of different components in M-BERT to its cross-lingual ability. We study the impact of linguistic properties of the languages, the architecture of the model, and the learning objectives. The experimental study is done in the context of three typologically different languages -- Spanish, Hindi, and Russian -- and using two conceptually different NLP tasks, textual entailment and named entity recognition. Among our key conclusions is the fact that the lexical overlap between languages plays a negligible role in the cross-lingual success, while the depth of the network is an integral part of it. All our models and implementations can be found on our project page: this http URL .
The Concept of Peace Education with Dialogic Teaching Approach in History Learning

Peace education is a necessity in creating a civil society in today's multicultural world. This article is an attempt to develop the concept and practice of peace education with dialogic teaching approach in history learning. This study used qualitative research method with literature review approach by analyzing articles related to the research corpus, i.e. peace education, dialogic teaching approach, controversial history, and history learning. The results of this study indicate that the dialogic teaching approach is an effective learning approach in teaching controversial historical material. The concept of peace education with dialogic teaching approach in teaching history consist of three learning domains, thus are teaching-learning, instruments, and assumption. The dialogic teaching approach can create a democratic dialogue between students-teacher and studentstudent so that students can build critical thinking skills, as well as responsibility and tolerance.Thus values are important in the peacebuilding process so that students are able to eliminate prejudice and build trust in the social community they are living.
University of Birmingham Computational implementation of a Hebbian learning network and its application to configural forms of acquired equivalence

We describe and report the results of computer simulations of the three-layer Hebbian network informally described by Honey, Close, and Lin (2010): A general account of discrimination that has been shaped by data from configural acquired equivalence experiments that are beyond the scope of alternative models. Simulations implemented a conditional principlecomponents analysis (CPCA) Hebbian learning algorithm and were of four published experimental demonstrations of configural acquired equivalence. Experiments involved training rats on appetitive bi-conditional discriminations in which discrete cues, (w and x) signaled food delivery (+) or its absence (-) in four different contexts (A, B, C and D): Aw+ BwCw+ DwAxBx+ CxDx+. Contexts A and C acquired equivalence. In three of the experiments acquired equivalence was evident from subsequent revaluation, from compound testing or from whole-/part-reversal training. The fourth experiment added concurrent bi-conditional discriminations with the same contexts but a pair of additional discrete cues (y and z). The congruent form of the discrimination, in which A and C provided the same information about y and z, was solved relatively readily. Parametric variation allowed the network to successfully simulate the results of each of the four experiments. Honey, R. , Close, J., & Lin, T. C. E. (2010). Acquired distinctiveness and equivalence: a synthesis. In C. Mitchell & M. Le Pelley. Oxford: Oxford University Press.
Nutritionists and the comprehensive care of overweight individuals in primary care

ABSTRACT Objective This study sought to highlight the different types of challenges for the integral care of overweight individuals in primary care based on the perception of nutritionists. Methods This is a qualitative study with primary care professionals from the Federal District, Brazil. Semi-structured interviews were conducted to understand the perceptions regarding the organization of integral care. The analysis of the data was based on the theoretical framework Theoretical Domains Framework. Results Challenges related to 10 of the 12 different domains proposed by the theoretical framework were identifi ed. These challenges are related to the capability, opportunity and motivation of workers to act to offer moreeffective care. Conclusion The different nature of the barriers identifi ed were overlapped, which reveal the need for professional qualifi cation along with the consolidation of an appropriate care model for chronic noncommunicable diseases such as obesity.
EFFECTS OF GROUND GRANULATED BLAST-FURNACE SLAG ON THE INDEX AND COMPACTION PARAMETERS OF CLAYEY SOILS

The use of industrial wastes in soil stabilization not only provides for the re-use of waste materials, which may cause environmental pollution, but also leads to cost benefits. In this context, the use of industrial wastes in the stabilization of fine-grained soils has become a research topic in recent years. The aim of this study is to evaluate the potential use of granulated blast-furnace slag (GBFS) in clayey soil stabilization. In this study, the GBFS obtained from the Iskenderun iron-steel plant as an industrial waste was ground into two different fineness levels, and the effects of their incorporation into lowplasticity Kolsuz clay and high-plasticity bentonite clay in various rates (5%, 10%, 20%, 30%, and 50%) on the particle weight of unit volume, the consistency limits, and the compaction parameters are investigated. Based on the experimental results, it is clear that the GBFS has a positive effect on the stabilization of both clayey soils. It was also concluded that the improvement in bentonite clay is greater than that in Kolsuz clay. Thus, GBFS seems to be a promising material for the stabilization of clayey soils.
Relationship between Partnering Process in Construction and Customer Satisfaction

Partnering Process in the construction sector is generally known as very simple and beneficial progress, which mainly aims to bring success for all the participants that take place during the project. Human factor and systematic working environment is observed as important components of the success of the partnering process. Individualistic characteristics of the human and dependency of systematic working environment toward human attitude leads a research necessity towards the human factor upon Partnering progress. When the studies over human characteristics have been generally observed, various researches have showed that emotional characteristic of the person has huge effect on the decision mechanism over the cases. Customer satisfaction is one of the cases that have been stated in various researches which try to explain market conditions according to human decisions and their triggering points. When these factor’s above considered its clear to see that there could be a relationship between Customer Satisfaction and Partnering Process in Construction. It is observed that the mutual relationship between the cases will either lead a successful cooperation in long term or unsuccessful ultimate point of the relation when the specific requirements and characteristics of the concepts have been taken into account.
ePubWU Institutional Repository

This article investigates the influence of competition on price and product quality among Austrian camping sites, a market characterized by both horizontal (spatial) and vertical product differentiation. Theoretically, the effect of competition on quality is ambiguous and depends on the degree of cost substitutability between output and quality. Estimating a system of equations shows that intense competition has a positive impact on product quality and a negative effect on prices (conditional on quality). As high quality is associated with high prices, the total effect of competition on prices is rather small.