Miracle-dz/UniFAR-FTUs huggingface dataset:
Early-life inflammatory markers and subsequent episodes of depression and psychotic experiences in the ALSPAC birth cohort

Background Inflammation is implicated in depression and psychosis, including association of childhood inflammatory markers on the subsequent risk of developing symptoms. However, it is unknown whether early-life inflammatory markers are associated with the number of depressive and psychotic symptoms from childhood to adulthood. Methods Using the prospective Avon Longitudinal Study of Children and Parents birth cohort (N=up-to 6,401), we have examined longitudinal associations of early-life inflammation [exposures: interleukin-6 (IL-6), C-reactive protein (CRP) levels at age 9y; IL-6 and CRP DNA-methylation (DNAm) scores at birth and age 7y; and IL-6 and CRP polygenic risk scores (PRSs)] with the number of depressive episodes and psychotic experiences (PEs) between ages 10-28 years. Psychiatric outcomes were assessed using the Short Mood and Feelings Questionnaire and Psychotic Like Symptoms Questionnaires, respectively. Exposure-outcome associations were tested using negative binomial models, which were adjusted for metabolic and sociodemographic factors. Results Serum IL-6 levels at age 9y were associated with the total number of depressive episodes between 10-28y (n=4,262; {beta}=0.086; 95%CI:0.036-0.137; pFDR=0.009). CRP DNAm score at birth was associated with total number of PEs, size but this association did not survive correction for multiple testing (n=822; {beta}=0.204; 95%CI:0.024-0.388; p uncorrected=0.027; pFDR=0.252). Other immune measures were not associated with depression or PEs. Conclusions Early-life inflammatory markers are associated with the burden of depressive episodes and of PEs subsequently from childhood to adulthood. These findings support a potential role of early-life inflammation in the aetiology of depression and psychosis and highlight inflammation as a potential target for treatment and prevention.
International Journal of Agriculture and Environmental Research

The study analyzed effects of farmers’ attitudes towards post-harvest losses of citrus in Ushongo Local Government Area of Benue State, Nigeria. Primary data were collected from 90 citrus farmers randomly selected using a structured questionnaire. Data were analyzed using descriptive and inferential statistics. Results showed that farmers experienced high post-harvest losses during harvesting (M=2.96), storage (M=2.48), gathering of fruits (M=2.38), transportation (M=2.34), packaging and bagging (M=2.31), wholesale market (M=2.24) and sorting (M=2.12). The losses were caused by improper harvesting (M=4.99), poor sanitation (M=4.98), pest and disease attacks (M=4.96), exposure of fruits to sun (M=4.81), high rate of bruising (M=4.75), poor handling (M=4.62), among others. The effects of losses on citrus included reduction in output (M=2.00), reduction in farmers’ income (M=2.00), poor taste (M=2.00) and so on. Farmers’ suggested storage of fruits in cool places (M=2.00), removal of dirts before packaging (M=2.00), among others as measures for reducing post-harvest losses in citrus. The study revealed that household size (0.064; p ≤, 0.078), level of education (-0.068; p ≤ 0.045) and citrus farming experience (0.001; p ≤, 0.084) significantly influenced extent of losses of citrus among farmers. The study further found that there exists a relationship (r=0.209) between farmers’ attitudes towards citrus production and extent of post-harvest losses of citrus. It was concluded that farmers experienced high post-harvest losses in citrus with great effects on their production and income but possessed positive attitudes for reducing losses of the fruits.
The Morality of Organization vs. Organized Members: Organizations are Attributed More Control and Responsibility for Negative Outcomes in the Organization Frame than the Members Frame

Seven experiments demonstrate that framing an organizational entity (the target) using an organization frame (“an organization comprised of its constituent members”) versus a members frame (“constituent members comprising an organization”) alters people’s attribution of responsibility to the target following a negative outcome, despite identical information conveyed. Specifically, the target in the organization (vs. members) frame was perceived to have more control over a negative outcome, which led to an increased attribution of responsibility (Studies 1-3). This effect surfaced for both for-profits and non-profits (Study 5). However, when the target in the members frame had explicit control over the outcome (Study 3), or when participants held strong beliefs in individual free will (Study 4), the effect of frame on responsibility attenuated. To the extent that framing increased perceptions of control, punishment for the target also increased (Studies 6a and 6b). By demonstrating how a subtle shift in framing can impact people’s perceptions and judgments of organizations, we reveal important knowledge about how people understand organizations and the psychological nature of organizational and group perception.
Institutional Knowledge at Singapore Management University The Art of Representation: How Reputation Affects Success with Different Audiences in the Contemporary Art Field

We study the effects of actors ’ audience-specific reputations on their levels of success with different audiences in the same field. Extending recent work that has emphasized the presence of multiple audiences with different concerns, we demonstrate that considering audience specificity leads to an improved understanding of reputation effects. Using data on emerging artists in the field of contemporary art from 2001 to 2010, we investigate the manner in which artists ’ audience-specific reputations affect their sub-sequent success with two distinct audiences: museums and galleries. Our findings suggest that audience-specific reputations have systematically different effects with respect to success with museums and galleries. Our findings also illuminate the extent to which audience-specific reputations are relevant for emerging research on the contingent effects of reputation. In particular, our findings support our predictions that audiences differ from one another in terms of the extent to which other signals (specifically, status and interaction with other audiences) enhance or reduce the value of audience-specific reputations. Our study thus advances theory by providing empirical evidence for the value of incorporating audience-specific reputations into the general study of reputation.
Key Success Factors of Community Health Workers Program in Garut, Indonesia

Aim: This study aims to investigate the experience of Indonesian community health workers (CHW) particularly in the aspect of motivation, advantages gained, obstacles and challenges related to the implementation of Saving Next Generation Institute (SNGI) program in Garut, Indonesia Methods: This study is a qualitative study. Semi-structured interviews were conducted with ten (10) community health workers who were enrolled in the program. Data were analyzed by using thematic analysis. Findings: The study reveals that the participating CHWs have positive experiences with the program. Respondents were motivated to gain comprehensive knowledge and skills from joining the program to serve their community better. Also, the CHWs acknowledged their getting more empowerment, skill-building, positive communication, self-satisfaction, and recognition from the program compared to the state program. Conflicts among the CHWs, the sustainability of the program, and the types of incentives such as transport fees and material incentives were mentioned to be the challenges in the program. Conclusion: This study substantiates what CHWs’ consider points of importance from the program. Points included are sharing synchronous common goals between CHWs and the program, having identified and appropriate program which meets the CHWs’ needs, having positive communication with all stakeholders and having suitable incentives. Findings from this study should be considered an insight for both non-state actors and the Indonesian government in order to ensure future improvement and program upscaling. Future research might expand to analyzing the dynamics of state and non-state interaction and organizational behavior which highlights communication among stakeholders in the program.
Multilevel Flash Memories: Channel Modeling, Capacities and Optimal Coding Rates

—This paper is concerned with channel modeling and capacity evaluation of the multilevel ﬂash memory with m levels. The m -level ﬂash memory is modeled as an m -amplitude- modulation channel with input-dependent additive Gaussian noise whose standard deviation depends on the channel input. The capacity as well as the optimal coding rate of an m -level ﬂash memory channel ( m -LFMC) is given. If the channel output is observed after a (ﬁnite) quantizer, then the channel is further transformed into a discrete memoryless channel, which yields an approximation of the capacity for the m -LFMC. Actually, the determination of the capacity for the m -LFMC can be transformed into a two-step optimization problem, which can be numerically solved by an alternating iterative algorithm. This algorithm delivers not only the optimal input/level distribution but also the optimal values of levels. This algorithm also delivers the optimized number of levels at any given voltage-to-deviation ratio. Numerical results are presented to show the consistency with well-known Smith’s results for the amplitude-limited AWGN channel and the applicability of the modeling method, and to reveal that a ﬁnite level quantization of the channel output for the m -LFMC suffers from a negligible loss of information rate compared to the capacity.
Complete Partitioning Policy with Different Handover Priority schemes for Multi-Class Traffic in LEO Mobile Satellite Systems

— In this paper, an analytical framework is developed to evaluate the performance of complete partitioning (CP) policy with two different handover priority schemes for multi-class traffic in Low Earth Orbit-Mobile Satellite Systems (LEO-MSS). The queuing of handover requests priority scheme is examined as the first priority scheme. Where, in the second priority scheme a combination of guard channel and handover request queuing priority schemes is developed.
Studies on wear behavior of AA2024-B 4 C composites

--- The present work, aims at investigating the wear properties of AA2024 alloy before and after introducing particulates. B 4 C particulate reinforced AA2024 alloy metal matrix composites were prepared by stir casting method. Weight fraction of the reinforcement was varied 0 to 6 wt. % of B 4 C in steps of 3 wt. %. For each composite, during processing the reinforcement particles were pre-heated to a temperature of 400 0 C and then dispersed into the vortex of molten AA2024 alloy. The micostructural characterization was done using scanning electron microscope, which revealed uniform distribution of B 4 C particles in Al matrix.Pin-on-disc wear testing machine was used to evaluate the wear of prepared specimens, in which a hardened EN32 steel disc was used as the counter face. The results revealed that the wear in terms of height loss was increased with increase in normal load and sliding speed for all the conditions. Further, wear studies also suggest that wear resistance of the AA2024-3 & 6 wt. % B 4 C composites was lesser than that of the AA2024 matrix.
Innovation, Institutional Development, and Insider Trading

A positive stock market valuation of a firm’s innovative assets grants the firm credibility as an innovator, facilitates the financing of future R&D, and is, therefore, an important step towards a firm’s ability to create and sustain a competitive advantage. Using a dataset of publicly listed firms in China, we show that in weak institutional environments innovative assets face a lower market valuation. We, further, show that insider trading acts as a signal for the value of innovative assets and increases the stock market valuation of innovative assets. Entrepreneurship, and Dynamics, Industry CIE2021 Research the CAED2021
Experimentally Validated Extension of the Operating Range of an Electrically Driven Turbocharger for Fuel Cell Applications

: From an aerodynamic point of view, the electric turbocharger for the air supply of an automotive fuel cell faces difﬁcult requirements: it must not only control the pressure level of the fuel cell, but it also has to operate with very high efﬁciency over a wide range. This paper explores features for the compressor and the turbine of an existing electric turbocharger, which are intended to meet the speciﬁc requirements of a fuel cell in an experimentally validated numerical study. Adjustable diffuser or nozzle vanes in the compressor and turbine achieve wider operating ranges but compromise efﬁciency, especially because of the necessary gaps between vanes and end walls. For the turbine, there are additional efﬁciency losses since the pivoting of the nozzle vanes leads to incidence and thus to ﬂow separation at the leading edge of the nozzle vanes and the rotor blades. An increase in the mass ﬂow and a slight efﬁciency improvement of the turbine with the low solidity nozzle vanes counteracts these losses. For the compressor, a reduction in the diffuser height and its inﬂuence over the operating range and power consumption yields an increase in surge margin as well as in maximum efﬁciency.
PHYTOCHEMICAL AND MOLECULAR STUDIES ON NARCISSUS IN EGYPT

This study was carried out in National Research Center in Dokki, Egypt in collaboration with Botany department, Faculty of Science, Mansoura University during 2007-2009 seasons. This study first, aims to find Egyptian wild narcissus bulbs for scientific records and genetic fingerprinting as an Egyptian species. Unfortunately the bulbs almost disappeared from about two decades under the pressure of tourism and ordinary cultivation in north coast of the country. Hopeless looking for any evidence it may be still found, but our search in many areas in Egypt fails to find any bulb. And so, the study continues based on another two species of narcissus foreign one Narcissus tazetta cultivated for many years in Egypt and a commercial variety from flowers producer. The other aim of our study was to carry out phytochemical screening to estimate the natural components of Narcissus tazetta plants and data showed that many constituents were found in the form of alkaloids including flavonoids, tannins, sterols and triperpenes. Finally, molecular studies using RAPD-PCR were carried out to fingerprint the two species of narcissus using ten 10-mer primers, indicating that unique fingerprinting bands as produced by primers number 1, 2 and 3 could clearly discriminate between the two species for example, fragments with approximately molecular size of 2764 bp, 2344 bp, 1114 bp, 978 bp and 792 bp were detected in Narcissus tazetta profile while, fragments with approximately molecular size of 1787 bp, 1996 bp, 1592 bp and 583 bp were detected in commercial narcissus profile.
Polyunsaturated fatty acid levels and the risk of keratinocyte cancer: A Mendelian Randomisation analysis.

Background: Keratinocyte cancer (KC) is the commonest cancer, imposing a high economic burden on the healthcare system. Observational studies have shown mixed associations between polyunsaturated fatty acids (PUFAs) and KC; basal cell carcinoma (BCC) and squamous cell carcinoma (SCC). We explored if genetically predicted PUFA levels are associated with BCC and SCC risks. Methods: We conducted a two sample Mendelian Randomisation study using PUFA level GWASs from the CHARGE consortium (n > 8,000), and the meta-analysis GWASs from UKB, 23andMe and Qskin for BCC ( n =651,138) and SCC ( n = 635,331) risk. Results: One standard deviation increase in genetically predicted levels of linoleic acid (OR = 0.94, 95% CI = 0.91-0.97, P = 1.4 × 10 -4 ) and alpha-linolenic acid (OR = 0.91, 95% CI = 0.86-0.96, P = 5.1 × 10 -4 ) was associated with a reduced BCC risk, while arachidonic acid (OR = 1.04, 95% CI = 1.02-1.06, P = 3.2 × 10 -4 ) and eicosapentaenoic acid (OR=1.10, 95% CI = 1.04-1.16, P = 1.5 × 10 -3 ) were associated with an increased BCC risk. Conclusion: Higher genetically predicted levels of linoleic acid and alpha-linolenic acid were associated with a reduced BCC risk, but arachidonic acid and eicosapentaenoic acid were associated with a higher BCC risk. Impact: PUFA related diet and supplementation could influence BCC aetiology. such as ROS- reactive oxygen species. LOX - lipoxygenase; COX-cyclooxygenases ( COX-1 and COX-2 ); PGE, prostaglandin E; ROS- reactive oxygen species; FADS2 -Fatty Acid Desaturase 2; FADS1 - Fatty Acid Desaturase 1.
An overview of ISCAT 2000

The Investigation of Sulfur Chemistry in the Antarctic Troposphere (ISCAT) took place over the timer period of 15 November to 31 December in the year 2000. The study location was the Amundsen Scott Station in Antarctica. ISCAT 2000 deﬁnes the second phase of a program designed to explore tropospheric chemistry in Antarctica. As in 1998, the 2000 ISCAT study revealed a strong oxidizing environment at South Pole (SP). During the 2000 investigation, however, the suite of measurements was greatly expanded. These new measurements established the recycling of reactive nitrogen as a critical component of this unique environment. This paper ﬁrst presents the historical background leading up to the ISCAT 2000 observations; then it focuses on providing a summary of the year 2000 results and contrasts these with those recorded during 1998. Important developments made during the 2000 study included the recording of SP data for several species being emitted from the snowpack. These included NO, H 2 O 2 and CH 2 O. In this context, eddy-diffusion ﬂux measurements provided the ﬁrst quantitative estimates of the SP NO and NO x snow-to-atmosphere ﬂuxes. This study also revealed that HNO 3 and HO 2 NO 2 were major sink species for HO x and NO x radicals. And, it identiﬁed the critical factors responsible for SP NO levels exceeding those at other polar sites by nearly an order of magnitude. Finally, it reports on the levels of gas phase sulfur species and provides evidence indicating that the absence of DMS at SP is most likely due to its greatly shorten chemical lifetime in the near vicinity of the plateau. It is proposed that this is due to the inﬂuence of NO on the distribution of OH in the lower free troposphere over a region that extends well beyond the plateau itself. Details related to each of the above ﬁndings plus others can be found in the 11 accompanying Special Issue papers.
A refined nonlocal hyperbolic shear deformation beam model for bending and dynamic analysis of nanoscale beams

This paper proposes a new nonlocal higher-order hyperbolic shear deformation beam theory (HSBT) for the static bending and vibration of nanoscale-beams. Eringen’s nonlocal elasticity theory is incorporated, in order to capture small size effects. In the present model, the transverse shear stresses account for a hyperbolic distribution and satisfy the free-traction boundary conditions on the upper and bottom surfaces of the nanobeams without using shear correction factor. Employing Hamilton’s principle, the nonlocal equations of motion are derived. The governing equations are solved analytically for the edges of the beam are simply supported, and the obtained results are compared, as possible, with the available solutions found in the literature. Furthermore, the influences of nonlocal coefficient, slenderness ratio on the static bending and dynamic responses of the nanobeam are examined.
Reveal Voluntary Auditor Switching Determinants in Indonesia: Evidence from Financial Services Sector

Many argue that factors affecting voluntary auditor switching by clients have not been common-ly agreed. This research attempts to investigate whether management change, company growth, the credibility of auditor, and audit tenure both simultaneously and partially influence voluntary auditor switching by auditee. We use public companies from financial services listed in the Indonesian Capital Market over period 2011-2016 as research objects. We conduct logistic regression to reveal whether relationship between those variables exists. Based on our analysis, we conclude that those four independent variables have no significant impacts on voluntary auditor rotation. This result not only confirms some previous studies but also contrary with a number of former researches. Therefore, we suggest that future research shall consider other variables such as good corporate governance components to obtain more convincing results.
1 Chromosome-encoded hemolysin, phospholipase and 2 collagenase contribute to virulence for fish in plasmidless 3 isolates of Photobacterium damselae subsp. damselae

25 Photobacterium damselae subsp. damselae is a pathogen of marine animals including 26 fish of importance in aquaculture. The virulence plasmid pPHDD1, characteristic of 27 highly hemolytic isolates, encodes the hemolysins damselysin (Dly) and phobalysin 28 (PhlyP). Strains lacking pPHDD1 constitute the vast majority of the isolates from fish 29 outbreaks, but genetic studies to identify virulence factors in plasmidless strains are 30 scarce. Here we show that the chromosome-I encoded hemolysin PhlyC plays a role in 31 virulence and cell toxicity in pPHDD1-negative isolates of this pathogen. By combining 32 the analysis of whole genomes and of gene deletion mutants, we identified two hitherto 33 uncharacterized chromosomal loci encoding a phospholipase (PlpV) and a collagenase 34 (ColP), respectively. PlpV was ubiquitous in the subspecies and exerted hemolytic 35 activity against fish erythrocytes which was enhanced in the presence of lecithin. ColP 36 was restricted to a fraction of the isolates, and was responsible for the collagen- 37 degrading activity in this subspecies. Consistent with the presence of signal peptides in 38 PlpV and ColP sequences, mutants for the type II secretion system (T2SS) genes epsL 39 and pilD exhibited impairment in the production of phospholipase and collagenase 40 activities. Sea bass virulence experiments and cell culture assays demonstrated a major 41 contribution of PhlyC and PlpV to virulence and toxicity. demonstrate that the plasmidless strains produce two hitherto uncharacterized 50 ubiquitous toxins encoded in chromosome I: the hemolysin PhlyC and the 51 phospholipase PlpV. We report a main role of these two toxins in fish virulence and in 52 cell toxicity. Our results constitute the basis for a better understanding of the virulence 53 of a widespread marine pathogen. (PlpV) and a gelatinase/collagenase (ColP). Our results revealed a main 96 role of the chromosomal hemolysin gene hlyA ch and the phospholipase gene plpV in fish 97 virulence and cell toxicity. In addition, we provide for the first time the complete with 3% egg yolk extract (Oxoid), and results were evaluated after 24 h of culture at 25ºC. The gelatinase activity assay was conducted by spotting 10 µl of a TSB-1 overnight culture onto TSA-1 plates supplemented with 1% gelatin (Oxoid), and results were developed after 48 h of incubation at 25 °C by covering the agar plate