Miracle-dz/UniFAR-FTUs huggingface dataset:
Investigating the Effect of TNF α (-863) and TNF α (-308) genes Polymorphism on the Progression of Disease in Patients with Cystic Fibrosis

Background: Recent studies have shown that the course of cystic fibrosis in patients with this disease differs despite the same mutation in CFTR gene. We aimed to investigate the role of polymorphism in TNF α (-308) and TNF α (-863), and its effect on the phenotype of the patients with cystic fibrosis and progression of disease. Materials and Methods: In this case-control study, 50 children with cystic fibrosis and 50 healthy children were examined for TNF-α-308 GA and TNF α - 863CA polymorphism.Four ml of citrated blood was taken from the patients in order to perform the DNA purifying and PCR-RFLP. With custom designed primers, PCR was done. Then with restriction enzymes PCR-RFLP was performed on the product of previous PCR. Changes were analyzed taking the following into consideration: diagnosis age, starting point of the pulmonary disease. Hb O2 saturation level, FEV1, and FVC. Also, for each of them, a Schwachman index basis score was calculated and results are mentioned. Results: Patient’s average age was 21±5.1 years old (ranged 5-26 years), and 48.9% (n=24) of patients were females. The average age at diagnosis was also 39.78 ±13.51 months. Patients with genotype TNF-α-308GA were older in diagnostic time compared to TNF-α-308GG genotype. However, for other variables, such as O2 sat, FEV1, FVC no difference was observed. Patients Heterozygote genotypes for “C” allele (CA) of TNF-863 have better Schwachman score than CC genotype. Conclusion The results of this research emphasize the importance of genetic factors affecting inflammatory processes. Identifying these variables is helpful in treating patients with cystic fibrosis disease.
Molecular characterization of some brinjal genotypes (Solanum melongena L) using simple sequence repeat (SSR) markers

To analyze genetic variability of 48 brinjal genotypes by Simple Sequence Repeat (SSR) markers, four primers named smSSR01, smSSR03, smSSR11 and smSSR14 were selected for analyze the data. Four primers generated clear bands and a total of 44 alleles were detected among the 48 brinjal genotypes (9.0 to 14.0 alleles per locus with a mean of 11.0 alleles per locus). According to Nei’s (1973), the highest level of gene diversity value 0.8672 was observed in loci smSSR11 and the lowest level of gene diversity value 0.6580 was observed in the loci smSSR14 with a mean diversity of 0.7847. As a measure of the informativeness of microsatellites, the PIC value ranges from a low of 0.6413 (smSSR14) to a high of 0.8536 (smSSR11) and averaged 0.7660. The genetic distance (GD) between genotypes was computed from combined data for the four primers, ranging from 0.250 to 1.000. The highest genetic distance (1.000) was observed between Morich Begun (Small) vs. Laffa (Long, Violet), Morich Begun (Small) vs. BARI Begun -1 and many other genotype pairs and also the lowest genetic distance (0.250) was found in Morich Begun (Small) vs. Pahoza-2, Morich Begun (Small) vs. BAU Begun-1, Singnath (Long, Violet) vs. Laffa BAU (Long, Violet), Borka (Long, Green) vs. Purple Long and many other genotype pairs. The Unweighed Pair Group Method with Arithmetic Means (UPGMA) cluster tree analysis lead to the grouping of the 48 genotypes into seven major clusters and the genotypes that are derivatives of genetically similar type form cluster together. Maximum brinjal genotypes include cluster IV. The SSR markers used in the present study were able to differentiate forty eight brinjal genotypes genetically. The results of the study suggested that SSR can be used as a suitable genetic marker to identify the brinjal genotypes. However, further studies involving large number of genotypes and primers need to be conducted to get more precise information and help enhance the knowledge of students and researchers relating to molecular characterization of other solanaceious crops. Key words: Brinjal, SSR, Genetic Diversity
Coherence of social practices: the case of meat consumption

Social practices are routine behaviour like going to work, cooking and showering which integrates different kinds of elements, such as bodily activities, material artefacts, skills and associated meaning. Understanding social practices is vital to address routine, collective and conventional consumption and the environmental effects associated with our daily lives. This article provides a contribution to a better understanding of social practices. It is hypothesised that practices that spread and persist in a considerable part of a society must be coherent: the elements involved are complementary in a way that a) implies cognitive consistency and that b) the individual has appropriate skills and knowledge to perform the respective behaviour. A literature review and a case-study on meat consumption practices provide confirmation of the hypothesis. The concept of coherence constitutes a promising starting point for future research on the emergence, spread and persistence of social practices.
Emotional and Behavioral Disorders in Pediatric Cancer Patients

Objectives Childhood malignancies raise a range of medical, psychological and social concerns. Identifying psychiatric disorders along with providing mental health services to prevent the emergence and aggravation of mental health problems in children seems necessary in pediatric hospitals. We aimed to find out the frequency of probable emotional and behavioral disorders among children and adolescents with malignancy. Materials & Methods This was a cross-sectional study conducted at the Hematology-Oncology Ward of Mofid Hospital, Tehran, Iran, during 2017-2018. Emotional and behavioral disorders were assessed in 399 pediatric cancer patients aged 5 to 12 years using the Parent Checklist of CSI-4. Results: Overall, 89.2% of the samples met the diagnostic criteria for at least one disorder. The most prevalent psychiatric disorders were specific phobia (57%), enuresis (41.9%), obsessive-compulsive disorder (45.6%) and separation anxiety disorder (30.3%). Our results did not show any significant relationship between gender or disease type and the prevalence of psychiatric disorders. Conclusion: The prevalence of emotional and behavioral disorders in pediatric cancer patients admitted to children’s hospitals is common. These disorders affect the treatment and quality of life of these patients. Therefore, our findings may guide parents, nurses and clinicians to become more cognizant of the identification and management of these disorders.
May passive dispersal of fungal enemies with native substrates in olive nurseries help to control phytonematodes?

Description of the subject. In Morocco, expanding agricultural sector under “Morocco Green Plan” will also introduce plant diseases and plant parasitic nematodes (PPN). Soil substrate used in most of the olive nurseries is potentially inhabited by PPN and natural enemies. Objectives. This work assessed the co-occurrence of PPN and nematophagous fungi (NF) in substrates and potential of NF to suppress PPN. Method. The diversity of PPN and NF genera was characterized in 305 substrate samples, isolated from 25 olive nurseries and functional activity (nematicidal and enzymatic) of NF was evaluated. Results. High PPN diversity was detected in the isolated samples and substrates were differentiated by NF activity. Global partition between PPN and NF diversity patterns confirmed prey-predator antagonism. Moreover, PPN-NF patterns depend on the fungal survival (saprophytes vs obligate parasites) and antagonism (predation vs toxicity) processes. However, even the NF strains with maximum fitness (growth, sporulation, enzymatic activity) were not inevitably the most effective against PPN. Consequently, it was hypothesized that predation and competition could be an adaptation process of NF to overcome environmental stress and exploit alternative or supplementary nutrient sources. Conclusions. The use of diverse native NF from cultivated and wild soils offer future prospects for the development of PPN management strategies in olive nurseries.
Degradation of CEX antibiotic from aqueous environment by US/S2O82-/NiO process: optimization using Taguchi method and kinetic studies

The extensive production and consumption of antibiotics have led to an increasing occurrence of antibiotic residuals in various aquatic compartments, presenting a significant threat to both the ecosystem and human health. This study aimed to investigate the removal of cephalexin (CEX) antibiotic from aqueous solutions by ultrasonic/persulfate/nickel oxide NPs (US/S2O8/NiO) hybrid process. To increase the removal efficiency, affecting parameters on the US/S2O8/NiO hybrid process were investigated and optimized by adopting the Taguchi design of experiments approach. The controllable factors such as solution pH, reaction time, initial concentration of CEX antibiotic, S2O8 concentration and NiO nanoparticle were optimized. Under optimum conditions (pH = 3, reaction time = 90 min, CEX = 20 mg/L, NiO = 5 mg/L and S2O8 = 400 mg/L) and using the US/S2O8/NiO process, the CEX, COD and TOC removal efficiencies were 96.05%, 68.02% and 47.14%, respectively. The studies to determine the percentage contribution of each controllable factor was also carried out. The pH of the solution was identified as the most influential factor, and its percentage contribution value was up to 70% in the studied process. Considering the parameters of the kinetics, it was found that the removal CEX antibiotic using the hybrid process obeys the pseudo-first-order kinetics. The results showed that US/S2O8/NiO hybrid process could be optimally used to treat the wastewater containing antibiotics such as CEX and could be considered as an effective and ecofriendly method.
DEFORMATION OF HIGHLY COMPRESSED WOUND ROLLS

R. C. Benson, J. E. LaFieche and K. D. Stack University of Rochester Rochester, NY, U.S.A. This study concerns tl1e loss oflap tension and interlayer pressure in a wound roll due to the compression of the web. Compression of the web thickness also aITects the amount of mate1ial that may be wound into a roll of a given diameter. Stress predictions are made using a new, nonlinear wound roll model developed by the Mechanics ofFlexible Shuctures Project at the University of Rochester. Compmison to e,pe1imenlal data available in the literature is excellenl We fmd that for some mate1ials such as polyethylene terephthalate (PET) the effect of web compressibility is relatively insignificant. For other materials, like paper, the effect is important.
Acceptance, Quality and Trust Factors â€“ Conceptual Model for Open Government Data Potential Use

To implement Big Data extensively in the public sector, many governments around the world are taking their initiative to ensure that Open Government Data (OGD) is a success. Even though the governments had provided thousands of datasets in the open data website, the level of use of open government data is still a question that has not been resolved. Therefore, the objective of this paper is to propose a new model of measuring the level of use of open government data. By integrating the Unified Theory of Acceptance and Use of Technology (UTAUT), IS Success Model (ISSM) and Trust factors, this new model perhaps can be a major contribution to the governments in ensuring that citizens are getting benefits from the datasets provided in the open data website.
The ‘ideal’ PE Kit to help reduce Body Image concerns within Adolescent Girls

Introduction: Adolescent girls typically possess dissatisfaction towards their bodies and is particularly prevalent when taking part within Physical Education (PE) lessons. It is therefore important to investigate whether the design of their own PE kit could have a positive effect on how they participate within PE. Methods: A sample of n = 40 female participants from Years 7 and 11 were recruited from two secondary schools, to provide a comparison. A non-validated questionnaire was designed to address the 3 research objectives using a Likert scale. Descriptive statistics and percentages were used for further analysis and interpretation. Results: 20% of Year 7 girls were most dissatisfied with their feet as opposed to 35% of Year 11’s with their upper arm. With regards to their current PE kit, Year 7 girls were least satisfied with shorts (20%) and Rugby shirt (25%), whereas, the Year 11’s were least satisfied with skirt and shorts (15%) and the polo shirt (15%). The design of the PE kit saw similarities between both Year 7 and 11, in particular where the designs covered up the body parts the participants were least satisfied with. Conclusion: Overall, girls would prefer a PE kit that was fitted, to allow for comfort and ease of movement, but also that covered certain body parts, including thighs and upper arm. By allowing girls to have a choice of their own PE kit, could help increase participation levels as they move through adolescence. Recommendations: Future research could involve all year groups within secondary schools.
EFFECT OF BISPHOSPHONATES ON THE ALVEOLAR BONE OF RATS WITH GLUCOCORTICOIDS INDUCED OSTEOPOROSIS

INTRODUCTION: Bone is a unique tissue that undergoes frequent remodeling. An imbalance between bone formation and resorption results in osteoporosis. Glucocorticoids (GCs) are widely used clinically as anti-inflammatory and immunomodulatory. However, their prolonged use may induce osteoporosis. Currently, evidences revealed that also the alveolar processes are subject to osteoporosis. Bisphosphonates, such as Alendronate, Risedronate and Zoledronate, are recommended by several international guidelines as the first-line therapy for the prevention and treatment of generalized glucocorticoids induced osteoporosis (GIOP). OBJECTIVES: To evaluate the effect of bisphosphonates (Risedronate) on the alveolar bone of rats with glucocorticoids induced osteoporosis. MATERIALS AND METHODS: Thirty female albino rats were divided into 3 equal groups (10 rats each) as follows: Group I: control group. Group II: glucocorticoids group (Dexamethasone 0.6mg/kg twice/week subcutaneously). Group III: Risedronate treated group; rats were given Dexamethasone (0.6mg/kg twice/week subcutaneously) and Risedronate (1mg/kg/day orally). After 12 weeks, rats were euthanized, and the mandibular alveolar bone was evaluated histologically by light microscope and ultra-structurally by scanning electron microscopy and energy dispersive X-ray (EDX) microanalysis. RESULTS: Group II showed deterioration of the alveolar bone in comparison to the control group I. The alveolar bone structure in Group III rats, treated by bisphosphonates (Risedronate), showed remarkable improvement both histologically and ultrastructurally in comparison to group II. Moreover, EDX analysis revealed a significant decrease of calcium levels in group II in comparison to group I. However, in group III calcium levels were restored to normal levels comparable to the control group I. CONCLUSIONS: Glucocorticoids intake induces loss of the alveolar bone; which, could be counterbalanced by bisphosphonates.
THE CORRELATION BETWEEN DEMAND FACTORS AND HEALTH CARE SERVICE UTILIZATION BY CONTRIBUTION BENEFICIARY PATIENTS

Background: National Health Insurance is the government's effort to increase public access to health care services. As the implementer of the National Health Insurance, the Outpatient Unit of Haji General Hospital, Surabaya has undergone the decrease of contribution beneficiaries’ visits from 2010-2013. This condition indicates a decrease in health care utilization by the low-income community.Aim: This study aims to identify the correlation between health care demands and health care utilization by the contribution beneficiary patients.Method: The study was an observational analytic using a cross-sectional design. A systematic random sampling technique was used to determine the sample of the study. The respondents were 74 contribution beneficiary patients who possessed a district government free care scheme and had ever utilized the health care services at the Outpatient Unit of Haji General Hospital, Surabaya, and at least 13 years old. The data were collected through questionnaires and analyzed with Spearman and Chi-Square tests (α =0.05). Results: Health status, insurance needs, additional costs, gender, ethnicity, education, and income did not have a significant correlation with the health care service utilization by the contribution beneficiary patients at the Outpatient Unit of Haji General Hospital. It was identified that the older the people are, the higher the frequency of health care utilization is. Besides, service time was proven to be the determinants of health care utilization (p = 0.006). Conclusion: The most influential factors in utilizing the health care services by contribution beneficiary patients are service time and age. Based on those factors, the Haji General Hospital requires to improve its services and service timeliness for the elderly contribution beneficiary patients.Keywords: demand, contribution beneficiary patients, utilization.
Role of packaging in consumer buying behavior

Article history: Received: October 26, 2019 Received in revised format: November 27 2019 Accepted: November 28, 2019 Available online: November 28, 2019 Every year about 95% of new products fail for a simple reason that most customers do not have the time or energy to think about the advantages or disadvantages of the products they place in their shopping carts, so they rely on shortcuts to make a purchase decision such as quality, beauty and excellence of product packaging. Packaging becomes part and parcel of our contemporary life especially in the continuous development for the conception of marketing. It becomes one of the basic dimensions for the concept of production because it plays big role to emphasize the mental image of the product on the consumer’s side. The importance of packaging leads several of marketing thinkers to consider it as enclosed marketing mix elements and one of corner stone in which goods depend on its success process. Therefore, the current study aims to study the concept and the importance of packaging and its role in attracting the consumer’s attention, and to determine the difficulties that the companies undergo in the field of packaging. The study depends on assembling the primary data on questionnaire designed especially for this purpose, and distributed to 600 consumers in Riyadh city. In addition to that secondary data is collected from resources related to the study subject. Simple statistical analysis is used to analyze the data. The results of research confirm the big role for the packaging in consumer attraction in study sample with all dimensions (design, color, size, and shape). The most important recommendation of the study is that to adopt a clear policy for packing in industrial organizations that cope with high technological development and the fast changing in consumer's tastes. It must be taken into the consideration the modern marketing orientations in product's packaging including the green marketing that depends on using material that has a little environmental effect at packaging process compared with traditional methods. © 2020 by the authors; licensee Growing Science, Canada
Islamophobic Discourses in Hillary Clinton’s Speech at Council of Foreign Relations during US- Presidential Elections 2016

Mohsin Hassan Khana*, Hamedi Mohd Adnanb, Haifa Aljuaidc, Roziah Mohamed Isad a,b(Media & Communication Studies, University of Malaya, Kuala Lumpur Malaysia, c(Faculty of Educational Studies, University Putra Malaysia, 43400 Seri Kembangan, Selangor, Malaysia, d(Gender Studies, University of Malaya, Malaysia, Email: aMohsin18516@gmail.com, bhamedi@um.edu. pk, chaifalii87@gmail.com d roziemohamed@yahoo.com
Characteristics of Ag Doped ZnO Thin Films Prepared by Sputtering Method

This paper presents results of preparation of Ag doped ZnO bulk sample by solid state reaction and Ag doped ZnO thin films by sputtering method. Effect of doping concentration (1, 2 and 4%) on the properties of the thin films was investigated. Various methods were utilized to investigate characteristics of the samples: X-ray diffraction, Raman scattering spectroscopy, photoluminescence, energy dispersive X-Ray spectroscopy, scanning electron microscopy, atomic force microscope, absorption spectroscopy and Hall measurement. The results show that Ag diffused into ZnO crystal lattice after heat treatment at 1200oC. As-prepared thin film samples exhibit low resistivity in the order of 10-3Ω. cm. The film doped with 2% Ag shows the lowest resistivity of 1.8´10-3Ω. cm which is potential for making transparent electrodes in optoelectronics.
Cross-sectional analysis of foreign direct investments (FDIs) in Albania

For developing countries, foreign direct investments (FDI) have had and continue to have an important role in meeting the strategic needs of the development of these countries. If a host country offers competitive advantages and untapped resources such as: lower production costs, unexploited natural resources, fiscal and legal incentives, etc., the development potential of FDI in that country will be very high. The main purpose of this paper is to provide an analysis of the performance of FDI with the focus in Albania as part of the Western Balkan. The paper reflects the connections between the macroeconomic indicators (GDP, GDP per capita, total tax rate, the distance between countries, and dummy variables) and the level of the stock of FDI in Albania. In order to explain these connections, it is used a cross-section analysis with a panel data of 21 origin countries of foreign investors in Albania, data are annual time series from 2007 to 2013. Furthermore, to analyze the existence of potential for attracting foreign investors in Albania likewise their concentration referred to economic activities or origin countries, it is used the analysis of Herfindal-Hirshman Index.
Determinant of Work Motivation and Supervisor Performance

The objective of this study was to analyse factors which, either partially or simultaneously, affect Work Motivation (MK) and Supervisor Performance (KS) of the companies gathered at Kawan lama Group, Indonesia. Descriptive and explanatory methods were used in this research, with an explanatory survey used as the approach. The population used in this study was 2844 persons, who were working in 6 companies of Kawan Lama Group in the entirety of Indonesia. The number of samples was decided based on Slovin formula, and as many as 351 persons were taken by proportional random sampling technique. Data analysis was performed by using SEM (Structural Equation Modelling) with the program of Linear Structural Relationship (LISREL 8.80). The result of this study recommended that the management of Kawan Lama Group enhances the variable of KS in order to prioritize improvement of variables of GK, especially in the dimension of participative leadership style, to be more specific to the indicator which consults and discusses problems with subordinates before making a decision. Whereas, to improve MK, the management should fix up the variable of BO, especially in the dimension of innovation and risk-taking, more specifically, the indicator of act innovatively.
Elderly patients and PD-L1-positive advanced non-small cell lung cancer: is pembrolizumab monotherapy effective and safe?

The administration of drugs acting on the immune system in order to improve the body’s ability to recognize and destroy cancer cells is really changing the history of lung cancer. In the pre-immunotherapy era, only 5.5% of patients with advanced non-small cell lung cancer (NSCLC) were alive 5 years after diagnosis and the majority of these patients did not exceed the year (1).