Miracle-dz/UniFAR-FTUs huggingface dataset:
Long term survival following a medical emergency team call at an Australian regional hospital

Objective: To investigate the long term survival of medical emergency team (MET) patients at an Australian regional hospital and describe associated patient and MET call characteristics. Design: Retrospective cohort study. Data linkage to the statewide death registry was performed to allow for long term survival analysis, including multivariable Cox proportional hazards regression and production of Kaplan–Meier survival curves. Setting: A large Australian regional hospital. Participants: Adult patients who received a MET call from 1 July 2012 to 3 March 2020. Main outcome measures: Survival to 30, 90 and 180 days; one year; and 5-years after index MET call. Results: The study included 6499 eligible patients. The cohort median age was 71 years, and 52.4% of the patients were female. Surgical (39.6%) and medical (36.9%) patients comprised most of the cohort. Thirty-day survival was 86.5% one-year survival was 66.1%. Among patients aged < 75 years, factors independently associated with significantly higher long term mortality included age (hazard ratio [HR], 3.26 [95% CI, 2.63–4.06]; for patients aged 65-74 v 18–54 years), male sex (HR, 0.71 [95% CI, 0.61–0.83]; for females) and pre-existing limitation of medical therapy (HR, 2.76; 95% CI, 2.28–3.35). Among patients aged ≥ 75 years, factors independently associated with significantly higher long term mortality included age (HR, 1.46 [95% CI, 1.29–1.65]; for patients aged ≥ 85 years), male sex (HR, 0.74 [95% CI, 0.66–0.83]; for females), and altered MET criteria (HR, 1.33; 95% CI, 1.03–1.71). Conclusions: Long term survival probabilities of MET call patients are affected by factors including age, sex, and limitation of medical therapy status. These data may be useful for clinicians conducting end-of-life discussions with patients.
Markers of Atrial Cardiopathy in Severe Embolic Strokes of Undetermined Source

Background and Purpose The current definition of embolic strokes of undetermined source (ESUS) seems to be too broad, including strokes due to heterogeneous mechanisms, such as atrial cardiopathy and other occult cardiac conditions, aortic arch plaques, and non-stenosing atherosclerosis, that can be differently associated with clinical stroke severity at the time of presentation. The aim of our study was to assess the possible association between neurological deficit severity and presence of markers of atrial cardiopathy in ESUS. Methods We retrospectively reviewed the medical records of a cohort of 226 ESUS patients (105 M, 121 F), that were divided into two groups according to the severity of neurological deficit (99 mild strokes with NIHSS ≤ 5 and 127 severe strokes with NIHSS >5). The following indices of atrial cardiopathy were evaluated: P wave dispersion, P wave max, P wave min, P wave mean, P wave index, P wave axis, left atrial size. Results Patients with severe ESUS were significantly older (74 ± 12 vs. 67 ± 14 years, P < 0.001) and female sex was prevalent (67 vs. 36%, P > 0.001); they had higher values of P-wave-dispersion (51 ± 14 vs. 46 ± 13, P = 0.01), P-wave-max (131 ± 20 vs. 125 ± 15 ms, P = 0.01), P-wave-index (16 ± 5 vs. 15 ± 5 ms, P = 0.01), left atrial size (20 ± 6 vs. 18 ± 4 cm2, P = 0.01), left atrial volume index (31 ± 14 vs. 27 ± 11 ml/m2, P = 0.04), in comparison with mild ESUS. An abnormal P wave axis was detected more frequently in severe ESUS (21 vs. 9%, P = 0.01). Furthermore, multivariate logistic regression showed that age (OR = 1.21 for each 5-year increase, 95% CI 1.09–1.35), sex (OR = 3.24 for female sex, 95% CI 1.82–5.76) and PWD (OR = 1.32 for each 10-ms increase, 95% CI 1.07–1.64) were the best subset of associated variables for severe ESUS. Conclusions Our findings shed light on specific clinical characteristics of severe ESUS including the presence of atrial cardiopathy that could play a pathogenic role in this subgroup of patients. Searching for atrial fibrillation in these patients is especially important to perform the most appropriate therapy.
Ophthalmoparesis and Bilateral Ptosis as a Rare Manifestation of Todd's Phenomenon: Case Report and Review

Todd's paresis or phenomenon (TP) is a focal weakness in a part of the body after a seizure. Seizure is an abrupt change in behavior caused by the cerebral cortex's electrical hyper-synchronization of neuronal networks. After the seizure, there is usually a transition period from the ictal state to the pre-seizure baseline level of awareness and function, referred to as the postictal period. Postictal symptoms include many systems, including sensory, motor, and psychosis. This phenomenon is named after Robert Bentley Todd, who first described it. Todd's paresis can be confused with other conditions, most commonly a stroke. Postictal ocular manifestation may be accompanied by aphasia or hemiplegia, but isolated gaze palsy is rarely reported. We are reporting a rare and first known isolated ophthalmoparesis and ptosis as postictal findings with no structural abnormalities present in imaging studies and complete resolution over three weeks on its own as an atypical postictal phenomenon. Patients with an underlying structural abnormality of the brain are more susceptible to Todd's phenomenon. Unusual manifestations of Todd's phenomenon are rare but clinically relevant and are decisive in therapeutic decision-making. Our patient presents a rare manifestation of Todd's phenomenon as ptosis and ophthalmoparesis in an elderly male with no underlying structural brain abnormalities that resolved within three weeks. Further research into the causes is needed to distinguish it from a stroke
Qualification, socialization, and subjectification: a discussion of the purpose of daily physically active learning through the lens of secondary school teachers

ABSTRACT Based on the fact that many youth do not meet global health recommendations for physical activity (PA), and that schools constitute an arena in which all children may be reached, PA integrated into school settings is critical. Inspired by the theoretical framework of Gert Biesta and his three domains of education, i.e. qualification, socialization and subjectification, this study examines secondary school teachers’ overall perceptions of the purpose of physically active learning (PAL) in secondary school. This is accomplished by using a longitudinal design, and interviewing 12 teachers three times – before, during, and after a PA school intervention that they organized. The analysis of the teachers statements revealed two main purposes that are related to the domain of qualification, two to the domain of socialization, and none to the domain of subjectification. However, the analysis showed that some perceptions are implicitly related to the domain of subjectification. Our findings correspond with the leading discourse, which highlights the importance of public health and academic outcomes in terms of PAL. We suggest, however, that the aim of implementing PA in schools should comprise all three domains of education, and that teachers must achieve a successful balance between different aims, and make decisions based upon desired results in upcoming pedagogical situations.
THM-coupled numerical analysis of temperature and groundwater level in-situ measurements in artificial ground freezing

Belarusian Potash salt deposits are bedded under aquifers and unstable soil stratums. Therefore, to develop the deposits a vertical mine shaft sinking is performed using the artificial ground freezing technology. Nowadays, real time observations of ground temperature and groundwater level is applied to control the ground freezing process. Numerical simulation can be used for a comprehensive analysis of measurements results. In this paper a thermo-hydro-mechanical model of freezing of water saturated soil is proposed. The governing equations of the model are based on balance laws for mass, energy and momentum for a fully saturated porous media. Clausius-Clayperon equation and poroelastic constitutive relations are adopted for description of a coupled change in water and ice pore pressure, porosity and a stress-strain state of freezing soil. The proposed model enables us to describe evolution of equivalent water content measured in Mizoguchi’s test and predict frost heave strain in one-sided freezing test. Numerical simulation of ground freezing in the Petrikov mining complex located in Belarus has shown that the model is able to describe field measurements of pore pressure inside a forming frozen wall. Furthermore, the mismatch between hydro- and thermo-monitoring data obtained during the artificial freezing is analyzed.
Assessment and Treatment for Coronary Microvascular Dysfunction by Contrast Enhanced Ultrasound

With growing evidence in clinical practice, the understanding of coronary syndromes has gradually evolved out of focusing on the well-established link between stenosis of epicardial coronary artery and myocardial ischemia to the structural and functional abnormalities at the level of coronary microcirculation, known as coronary microvascular dysfunction (CMD). CMD encompasses several pathophysiological mechanisms of coronary microcirculation and is considered as an important cause of myocardial ischemia in patients with angina symptoms without obstructive coronary artery disease (CAD). As a result of growing knowledge of the understanding of CMD assessed by multiple non-invasive modalities, CMD has also been found to be involved in other cardiovascular diseases, including primary cardiomyopathies as well as heart failure with preserved ejection fraction (HFpEF). In the past 2 decades, almost all the imaging modalities have been used to non-invasively quantify myocardial blood flow (MBF) and promote a better understanding of CMD. Myocardial contrast echocardiography (MCE) is a breakthrough as a non-invasive technique, which enables assessment of myocardial perfusion and quantification of MBF, exhibiting promising diagnostic performances that were comparable to other non-invasive techniques. With unique advantages over other non-invasive techniques, MCE has gradually developed into a novel modality for assessment of the coronary microvasculature, which may provide novel insights into the pathophysiological role of CMD in different clinical conditions. Moreover, the sonothrombolysis and the application of artificial intelligence (AI) will offer the opportunity to extend the use of contrast ultrasound theragnostics.
An Analysis of the Relationship between Resilience and Clinical Competence in Nurses : Descriptive-analytical Study

Objective: Resilience and clinical competence are two important components of providing nursing care to patients. The goal was to determine the correlation between clinical competence and resilience in the nurses at Babol University of Medical Sciences. Methods: This descriptive and correlational study was conducted in 2019-20. A total of 424 nurses working in the intensive care units and general wards of six hospitals affiliated with Babol University of Medical Sciences were selected using the stratified sampling technique. Liou’s Nursing Clinical Competence Questionnaire was used to assess the clinical competence of the nurses, and Connor-Davidson Resilience Scale was used to assess the nurses’ resilience. The descriptive statistics, Pearson’s correlation coefficient, t student, and one-way ANOVA methods were used in data analysis. Results: The mean score on the seven dimensions of clinical competence was high (174.8624.19). The nurses had the highest mean scores on “clinical care” and “management and leadership” dimensions (4.7731.50, 4.728.61) in the order mentioned. They also had the lowest mean scores on the “mentoring and teaching” and “professional progress” dimensions in the order mentioned (3.5319.10, 3.4119.14). The meanstandard deviation of the nurses’ resilience score was 73.3612. 66. The results of Pearson’s correlation test indicated a positive significant relationship between all clinical competence dimensions and nurses’ resilience (p<0.001, r=0.493). Conclusion: Given the strong relationship between resilience and clinical competence, nursing managers are recommended to carry out proper planning to improve the clinical competence and resilience of nurses.
Commentary: Chinese as a Second Language Multilinguals' Speech Competence and Speech Performance: Cognitive, Affective, and Sociocultural Perspectives

Citation: Ma C, Zhang S and Li C (2022) Commentary: Chinese as a Second Language Multilinguals’ Speech Competence and Speech Performance: Cognitive, Affective, and Sociocultural Perspectives. Front. Psychol. 13:935909. doi: 10.3389/fpsyg.2022. 935909 Commentary: Chinese as a Second Language Multilinguals’ Speech Competence and Speech Performance: Cognitive, Affective, and Sociocultural Perspectives
Knowledge and Beliefs regarding Seasonal Influenza Vaccine among Pregnant Women Attending Antenatal Clinics

Background: Seasonal influenza during pregnancy is a potentially life-threatening illness. It is associated with an increased risk for both mother and fetus, as; respiratory and cardio-pulmonary hospitalization, pre-term delivery, fetal distress, and death. The current study aims to assess knowledge and beliefs regarding seasonal influenza vaccine among pregnant women attending antenatal clinics. Methods: A descriptive correlational research design was adopted for this study to achieve the study aim. Tool: Three tools were used to collect the data; 1) structured interviewing questionnaire schedule, 2) seasonal Influenza knowledge assessment tool, and 3) influenza vaccine beliefs scale. Sample: A purposive of 160 pregnant women was enrolled in the study. Setting: the study was conducted at the outpatient antenatal clinics, maternity hospital, Cairo University, Egypt. Results: The mean age of the study sample was 29.98 ± 6.107 years. About 45.6% of them had primary and secondary education with more than half of the study sample were working (51.9%). More than half of the study sample (51.9%) had a sufficient level of knowledge with a positive beliefs regarding seasonal influenza vaccine during pregnancy. The barrier of pregnant women not taking the vaccine was; expensive; women not welling and fears from safety of the vaccine. Conclusions: Pregnant women had a sufficient level of knowledge and positive beliefs regarding influenza vaccination during pregnancy. Recommendations: These findings are important in tailoring educational programs and addressing the training needs of increase awareness regarding seasonal influenza during pregnancy for all women attending outpatient clinics. Also, the obstetricians should be highlighted the need for a national policy for the use of vaccines during pregnancy.
Modelling and experimental investigations of composition-dependent heat and mass transfer during Cu–Ni alloy nanoparticle synthesis in a transferred arc helium plasma

In the synthesis of alloy nanoparticles (NPs) via arc evaporation and fast quenching, the composition of the synthesized NPs differs significantly from that of the precursor. The properties of the NPs formed following evaporation of a copper–nickel anode by a helium arc are investigated using a nucleation model coupled to the thermal and flow fields derived from a magneto-hydrodynamic simulation of the arc, and experimentally. Results are obtained for three different Cu:Ni precursor compositions, 10:90, 50:50 and 90:10 at%. The synthesized particles are spherical with different size distributions and have a higher concentration of Cu than the precursor in all three cases, in contrast to previous observations, but in accordance with the predictions of the model. Emission spectroscopic measurements of copper and nickel lines indicate that the concentration of atomic copper in the plasma region near the anode is much higher than that of the nickel, in accordance with the predictions of the model. The higher vapour pressure of copper compared to nickel, and its higher activity in the alloy precursor (anode), immersed in a self-consistent thermal and flow field maintained by the transferred arc are found to play a critical role. The thermodynamic, radiative and transport properties of the helium plasma contaminated with evaporated precursor are important in determining the thermal and flow fields.
Glomerular Filtration and Proteinuria as a Cardiovascular Risk

An estimated 10% of the American population has some degree of renal disease, although asymptomatic. In Brazil, no data are available on the prevalence of chronic renal d isease. A number of studies show a direct and close relationship between the degree of renal dysfunction and Cardiovascular Disease (CVD) risk. Th is increased CVD risk, despite being maximal in end-stage renal failu re, begins to be noticed with slight declines in renal function. In addition, the presence of renal in jury, even with normal renal function, evidenced by proteinuria or microalbuminuria, is also a potent CVD risk factor. At present, the primary causes of renal disease are diabetic nephropathy and hypertensive nephrosclerosis, accelerated by cigarette smoking and dyslipidemia. Hence, increased CVD risk in patients with chronic kidney disease may be secondary to the accumulation of these classical risk factors; however, frequency of CVD events in these patients is higher than that predicted by equations that take into account such classical factors. Therefore, there may be mechanis ms intrinsic to renal lesion capable of accelerating systemic atherosclerosis. Accordingly, uremic toxicity itself, increased oxidative stress, change in the coagulation cascade, changes in lipid levels and hypervolemia are involved in the genesis of early atherosclerosis in patients with chronic kidney disease. It is incumbent on clinicians, nephrologists, hypertension specialists, and cardiologists to identify these patients through urinalysis, serum creatinine measurement, and microalbuminuria screening in order to reduce, through intensive treatment, to revert at least in part, the high CVD risk o f that diseased portion of the population.
Spatholobus suberectus Dunn Water Extract Ameliorates Atopic Dermatitis–Like Symptoms by Suppressing Proinflammatory Chemokine Production In Vivo and In Vitro

S. patholobus suberectus Dunn, a traditional Chinese herbal medicine, has various pharmacological activities, such as anti-inflammatory properties. However, to the best of our knowledge, its therapeutic effect on atopic dermatitis (AD) has not been investigated. In this study, we explored the effect of S. suberectus Dunn water extract (SSWex) on AD in vivo and in vitro. In Dermatophagoides farina extract (DfE)–treated NC/Nga mice, the oral administration of SSWex alleviated AD-like symptoms, such as ear thickness, dermatitis score, epidermal thickness, immune cell infiltration, and levels of AD-related serum parameters (immunoglobulin E, histamine, and proinflammatory chemokines). In HaCaT cells, the production of proinflammatory chemokines induced by interferon-γ (IFN-γ) and tumor necrosis factor-α (TNF-α) was inhibited by SSWex pretreatment. SSWex treatment inhibited the phosphorylation of mitogen-activated protein kinase and activation and translocation of transcriptional factors, such as signal transducer and activator of transcription 1 and nuclear factor kappa B in IFN-γ/TNF-α–stimulated HaCaT cells. These results indicate that SSWex may be developed as an efficient therapeutic agent for AD.
Practical Training Health Hazards among Secondary Technical Nursing Students

Background: Health hazards are a neglected public health issue among nursing students in developing countries. This has exposed nursing students in developing countries to various forms of hazards which had negative consequences on their wellbeing and performance at work. Aim of study: Was to assess practical training health hazards among secondary technical nursing students. Research design: A descriptive design was used to carry out this study. Setting: This study was conducted at two secondary Technical Nursing Schools in Benha City. Sample: Convenient sample included 222 nursing students. Tools: Two tools were used in this study, Tool I: A structured interviewing questionnaire to assess nursing students socio demographic characteristics, practical training health hazards facing nursing students, health problems that acquired after joining with secondary technical nursing schools and nursing students knowledge regarding practical training health hazards and protective measures Tool II: Observational checklist to assess nursing students practices toward protective measures. Results: 67.6% of studied nursing students exposed to stress as psychological hazards, 64.4% of them exposed to noise as physical hazards in addition to, 53.6% of them exposed to chemical hazards as latex powder that found in the gloves and 44.1% of them exposed to ergonomic hazards as carrying tools and supplies. 87.4% of them had back pain and neck pain, 45.5% &42.8% had stress and skin allergy respectively. 26.1% of them had good knowledge regarding practical training health hazards and protective measures. 77.9% of them had satisfactory practices. Conclusion: There were highly statistical significance relation between total knowledge level and total practices level. Recommendation: Develop and implementing health education and training programs to upgrade the nursing students' knowledge and practice toward health hazards associated with practical training.
Relationship Between Mortality and Seizures After Intracerebral Hemorrhage: A Systematic Review and Meta-Analysis

Background The relationship between mortality and seizures after intracerebral hemorrhage (ICH) has not yet been understood until now. A meta-analysis was performed to assess the effect of post-ICH seizures on mortality among patients with ICH. Methods PubMed and Embase were searched from the establishment of the databases to December 2021 to identify literature that evaluated the relationship between post-ICH seizures and mortality in ICH. Crude odds ratios and adjusted odds ratios with a 95% confidence interval (CI) were pooled using a random-effects model. Results Thirteen studies involving 245,908 participants were eventually included for analysis. The pooled estimate suggested that post-ICH seizures were not associated with significantly increased mortality in patients with ICH (crude odds ratios 1.35, 95% CI: 0.91–2; adjusted adds ratios 1.22, 95% CI: 0.78–1.88). However, the relationship was not consistent in subgroup analysis or robust in a sensitivity analysis. Conclusions This meta-analysis proved that post-ICH seizures were not associated with significantly increased mortality in patients with ICH. However, this result could be influenced by confounding factors, so more high-quality research is needed.