Miracle-dz/UniFAR-FTUs huggingface dataset:
EFFECTS OF AQUEOUS STEM BARK EXTRACT OF XYLOPIA AETHIOPICA ON THE REPRODUCTIVE FUNCTIONS OF MALE RATS

Objective: The sexual stimulatory effect of aqueous stem bark extract of Xylopia aethiopica which is commonly used traditionally for the treatment of fertility-related problems in males is reported in this work. Methods: The present study investigated the effect of 14 d oral administration of 1 ml/kg distilled water (control), 100, 200 and 300 mg/kg of body weight of the stem bark extract on some fertility parameters of the Swiss male rats. So, all the target organs (testis, epididymis, vas deferens, seminal vesicle and prostate) were weighed. The sperm motility and sperm count in testis, epididymis and vas deferens were determined. Serum and tissue protein, as well as cholesterol, were evaluated. The serum testosterone level was also assessed. Results: The extract did not produced significant change in the mobility of sperm, the sperm count in vas deferens, the relative weight of body and accessory organs at all doses. The daily sperm production (DSP) and the weight of prostate significantly increased at a dose of 100 mg/kg (p<0.01) while the sperm count in cauda epididymis increased at a dose of 200 mg/kg. The testicular and serum cholesterol significantly increased (p<0.001) at the dose of 100 mg/kg whereas the testicular and serum proteins increased (p<0.001) at the dose of 200 mg/kg. The serum testosterone level increased following 14 d of treatment (p<0.01) at the dose of 100 mg/kg. Conclusion : The results suggest that Xylopia aethiopica may have the potentials of being developed into a male fertility enhancing drug.
Ehrenfest time and chaos

The Ehrenfest time gives the scale of time on which the Bohr correspondence principle (Bohr, 1920) remains valid for a quantum evolution of an initial state at high characteristic quantum numbers (or small effective Planck constant ) closely following the corresponding classical distribution. For a narrow initial wave packet the Ehrenfest theorem (Ehrenfest, 1927) guaranties that the average values of quantum operators are close to the corresponding classical averages. For systems with integrable classical dynamics the Ehrenfest time is rather long being generally inversely proportional to the Planck constant (or another power of it). The new nontrivial situation appears for classically chaotic dynamics when nearby trajectories diverge exponentially with time due to exponential instability of motion characterized by the positive Kolmogorov-Sinai entropy . Thus in such semiclassical systems the Ehrenfest time is logarithmically short . The properties of the Ehrenfest time of quantum dynamics of such chaotic systems, with related examples, are discussed below.
A Search Method for Reassembling the Elements of a Broken 2D Object

Searching for and reassembling the elements that used to form one whole is a very common issue faced by archaeologists. This is because preparing an interesting museum exhibition consists in the presentation of the objects that have been put together, not a pile of messily disassembled puzzle pieces. The article presents the concept of using the linguistic methods in the process of joining the elements of a 2D jigsaw puzzle. The method developed in the first stage creates the edge description of an object by defined unit vectors of the same length but different directions, and assigns them a designation in the form of letters, which leads to the creation of abstract words in the form of a sequence of signs. In the second stage, the words with a defined length of strings belonging to two different objects are compared. The authors have created a program that performs an exhaustive search until the pool of available elements is fully exhausted. The conducted numerical experiments indicate the correctness of the method and effectiveness in determining the places of joining elements. The developed method will be useful to automate the reassembly of 2D elements from archaeological excavations.
PENGEMBANGAN INSTRUMEN TES KEMAMPUAN BERARGUMENTASI PADA MATERI IMPULS DAN MOMENTUM

ABSTRACT The ability to argue is an ability that needs to be mastered by students to pass on their knowledge to others. This study aims to develop a test instrument for the ability to argue on impulse and momentum material. The test instrument was adapted from the Toulmin's Argument Pattern (TAP) model. This research includes research and development by taking a 3-D model that is define, design, and develop. A total of five items of description are made based on indicators of argumentation ability. In the results of expert validation it is obtained that the test instrument is feasible to be developed by considering the improvement of the items by expert advice. The results of the development of the whole item is valid, and has a high reliable value of 0.78. Keywords : development of instruments, the ability to argue, impulses and momentum.
Sleep quality and duration following evening intake of alpha-lactalbumin: a pilot study#

Abstract Tryptophan loading enhances sleep quality by increasing the ratio of plasma tryptophan to large neutral amino acids (TRP:LNAA) and consequently synthesis and availability of serotonin in the brain. Alpha-lactalbulmin (A-LAC) is rich in tryptophan and has the highest TRP:LNAA of all protein sources. This pilot study investigated the effect of an evening intake of A-LAC on objective and subjective sleep measures in male subjects without sleep complaints. Ten healthy male university students (aged: 26.9 ± 5.3 years; BMI: 21.7 ± 1.9 kg.m−2) participated in a double-blind, randomized, and placebo-controlled crossover counter-balanced study. Objective (actigraphy) and subjective (sleep log) sleep measures were recorded for two nights after a standardized evening meal supplemented with either A-LAC (20 g) or a placebo of sodium caseinate (20 g) one hour before bedtime. Evening A-LAC intake resulted in increased objective and subjective total sleep time by 12.8% (p = 0.037) and 10.8% (p = 0.013), respectively, compared to placebo. Objective sleep efficiency increased by 7.0% (p = 0.028) following A-LAC with no significant effects for other sleep indices. This pilot study demonstrates the efficacy of evening A-LAC intake on sleep quality in young healthy adults, however further large-scale studies are warranted to confirm the benefit.
Poisson Weighted Ishita Distribution: Model for Analysis of Over-Dispersed Medical Count Data

Abstract A new over-dispersed discrete probability model is introduced, by compounding the Poisson distribution with the weighted Ishita distribution. The statistical properties of the newly introduced distribution have been derived and discussed. Parameter estimation has been done with the application of the maximum likelihood method of estimation, followed by the Monte Carlo simulation procedure to examine the suitability of the ML estimators. In order to verify the applicability of the proposed distribution, a real-life set of data from the medical field has been analysed for modeling a count dataset representing epileptic seizure counts.
The High-energy Radiation Environment around a 10 Gyr M Dwarf: Habitable at Last?

Recent work has demonstrated that high levels of X-ray and UV activity on young M dwarfs may drive rapid atmospheric escape on temperate, terrestrial planets orbiting within the habitable zone. However, secondary atmospheres on planets orbiting older, less active M dwarfs may be stable and present more promising candidates for biomarker searches. In order to evaluate the potential habitability of Earth-like planets around old, inactive M dwarfs, we present new Hubble Space Telescope and Chandra X-ray Observatory observations of Barnard’s Star (GJ 699), a 10 Gyr old M3.5 dwarf, acquired as part of the Mega-MUSCLES program. Despite the old age and long rotation period of Barnard’s Star, we observe two FUV (δ130 ≈ 5000 s; E130 ≈ 1029.5 erg each) and one X-ray (EX ≈ 1029.2 erg) flares, and we estimate a high-energy flare duty cycle (defined here as the fraction of the time the star is in a flare state) of ∼25%. A publicly available 5 Å to 10 μm spectral energy distribution of GJ 699 is created and used to evaluate the atmospheric stability of a hypothetical, unmagnetized terrestrial planet in the habitable zone (rHZ ∼ 0.1 au). Both thermal and nonthermal escape modeling indicate (1) the quiescent stellar XUV flux does not lead to strong atmospheric escape: atmospheric heating rates are comparable to periods of high solar activity on modern Earth, and (2) the flare environment could drive the atmosphere into a hydrodynamic loss regime at the observed flare duty cycle: sustained exposure to the flare environment of GJ 699 results in the loss of ≈87 Earth atmospheres Gyr−1 through thermal processes and ≈3 Earth atmospheres Gyr−1 through ion loss processes. These results suggest that if rocky planet atmospheres can survive the initial ∼5 Gyr of high stellar activity, or if a second-generation atmosphere can be formed or acquired, the flare duty cycle may be the controlling stellar parameter for the stability of Earth-like atmospheres around old M stars.
BANK 4.0 EXPERIENTIAL QUALITY AND ITS EFFECT ON WORD OF MOUTH BEHAVIOR, SATISFACTION AND INTENTIONS

Bank 4.0 is a modern banking platform that is based entirely on digital technology with absolutely no physical interaction between customers and banks. Since 2017, Bank 4.0 has grown rapidly in Indonesia. However, it raises new concerns as the emergence of issues related to Bank 4.0 experiential quality. This research aims at determining the effects of Bank 4.0 experiential quality on word of mouth behavior, customer satisfaction and continuance intention based on perception of millennial customer in Indonesia. Quantitative method was used in this research by using the multivariate data analysis technique. Data collected from 673 millennial customers who have access to Bank 4.0 applications. This research discovered that Bank 4.0 experiential quality has been empirically proven to directly affect word of mouth behavior, customer satisfaction and continuance intention. This research is the first study that explored Bank 4.0 experiential quality and its effects on three main variables in marketing, namely, word of mouth behavior, continuance intention, and customer satisfaction, based on millennial customer perceptions. The results from this study can help Bank 4.0 to improve marketing performance through experiential quality.
Iranian Students’ Attitudes toward International Agricultural Issues: A Case Study of Agricultural Extension and Education Students

Outdoor experiments on a once-through single glazed solar air heater with perforated metal absorber plate were conducted to determine the practical effect of absorber plate porosity as well as suction air flow rate on the collector thermal efficiency and its total pressure drop. Three aluminum absorber plates were made perforated by drilling circular holes with different diameter/pitch ratios in square layout. A fan was employed at the top of the collector to suck ambient air from the bottom side through absorber plate perforations. The flow channel was designed such that uniform air flow over the entire absorber plate area could be achieved. Five levels of air mass flow rates (0.0065 to 0.0321 kg m -2 s -1 ) were adopted. Pressure drop across the apparatus was measured. The inlet air was preheated by short wavelength radiation absorbed by the cover as well as the long wavelength emission by the absorber prior to catching the heat from transpired absorber plate. A maximum thermal efficiency of 84% could be achieved for the most part of the porous absorber plate at the highest air mass flow rate. The collector with minimum porosity showed a maximum pressure drop. In some experiments, the glass cover was removed to determine the outdoor effect of glazing. Comparing the performance of the collector with and without glazing showed that the unglazed collector was about 25% less efficient than the glazed one at the same overall operating conditions. This reduction can be attributed to high top radiative and convective heat losses for the unglazed collector at the outdoor conditions. The pressure drop for the uncovered collector showed a lower magnitude in comparison to the covered one. The inlet air passes and heats up (21-59°C above the ambient) through the solar collector, therefore the fresh and clean hot air can be continuously supplied for many purposes such as solar drying system.
The uracil-DNA glycosylase UNG protects the fitness of normal and cancer B cells expressing AID

Abstract In B lymphocytes, the uracil N-glycosylase (UNG) excises genomic uracils made by activation-induced deaminase (AID), thus underpinning antibody gene diversification and oncogenic chromosomal translocations, but also initiating faithful DNA repair. Ung−/− mice develop B-cell lymphoma (BCL). However, since UNG has anti- and pro-oncogenic activities, its tumor suppressor relevance is unclear. Moreover, how the constant DNA damage and repair caused by the AID and UNG interplay affects B-cell fitness and thereby the dynamics of cell populations in vivo is unknown. Here, we show that UNG specifically protects the fitness of germinal center B cells, which express AID, and not of any other B-cell subset, coincident with AID-induced telomere damage activating p53-dependent checkpoints. Consistent with AID expression being detrimental in UNG-deficient B cells, Ung−/− mice develop BCL originating from activated B cells but lose AID expression in the established tumor. Accordingly, we find that UNG is rarely lost in human BCL. The fitness preservation activity of UNG contingent to AID expression was confirmed in a B-cell leukemia model. Hence, UNG, typically considered a tumor suppressor, acquires tumor-enabling activity in cancer cell populations that express AID by protecting cell fitness.
EXTENDED TAM TEST ON INDONESIAN SMEs’ FINTECH USERS & ITS FINANCIAL REPORTS

Indonesia have SME accounting standard that effective in 2018, but this standard adoption is not popular at that time. Hence recent fastest growing in financial technology adoption by food industries’ SME creating the need for having financial reports in order to make an exact reconciliation for the payment. This research wants to know whether this financial technology usage will lead to SME’s to make financial reports according to accounting standard. The model is designed to test the Extended Technology Acceptance Model (Extended-TAM). Population here is SME in food industry that on Grabfood list. 100 sample were drawn using purposive sampling for SME that uses OVO, a financial technology company that partnering with Grabfood. Data then analyzes using WarpPLS.This results is consistent with Extended TAM. The result also shows that adoption of FinTech will trigger SME to make better financial reports to make reconciliation process in billing easier.
Leadership Self-Efficacy and Organizational Commitment of Faculty Members: Higher Education

Education is one of the means of achieving sustainable development. Universities are responsible for training and generating skilled personnel needed in attaining holistic development; to accomplish the goals for which universities were established, effective leadership is required. The beliefs upheld by leaders about their ability to accomplish targets and deliver as expected is an indispensable constituent of university administration. Therefore, this research study examined connections between leaders’ self-efficacy and faculty members’ organizational commitment in Saudi Arabian universities. Therefore, 400 faculty members were randomly selected from three different public universities in the central, south-western and northern part of the country. Using the Pearson product correlation coefficient, it was found that positive connection occurs amongst leaders’ self-efficacy and affective commitment. Additionally, there is a positive association among leaders’ self-efficacy and continuance commitment. Leadership self-efficacy has a positive connection with normative commitment. In order to improve organizational commitment of faculty members, leaders must step up their self-efficacy and provide an enabling environment for team work and innovation.
Resistance and resilience of social–ecological systems to recurrent typhoon disturbance on a subtropical island: Taiwan

Tropical cyclones (TCs) have major effects on ecological and social systems. However, studies integrating the effects of TCs on both social and ecological systems are rare, especially in the northwest Pacific, where the frequency of TCs (locally named typhoons) is the highest in the world. We synthesized studies of effects of recurrent typhoons on social and ecological systems in Taiwan over the last several decades. Many responses to TCs are comparable between social and ecological systems. High forest ecosystem resistance, evident from tree mortality below 2% even following multiple strong typhoons, is comparable with resistance of social systems, including the only 4% destruction of river embankments following a typhoon that brought nearly 3000 mm rainfall in three days. High resilience as reflected by quick returns of leaf area index, mostly in one year, and streamwater chemistry, one to several weeks to pre-typhoon levels of ecosystems, are comparable to quick repair of the power grid within one to several days and returns of vegetable price within several weeks to pre-typhoon levels of the social systems. Landslides associated with intense typhoons have buried mountain villages and transported large quantities of woody debris to the coast, affecting the coastal plains and reefs, illustrating a ridge-to-reef link between ecological and societal systems. Metrics of both social and ecological function showed large fluctuations in response to typhoons but quickly returned to pre-disturbance levels, except when multiple intense typhoons occurred within a single season. Our synthesis illustrates that the social–ecological systems in Taiwan are highly dynamic and responsive to frequent typhoon disturbance, with extraordinarily high resistance and resilience. For ecosystems, the efficient responsiveness results from the selective force of TCs on ecosystem structure and processes. For social systems, it is the result of the effects of TCs on planning and decision making by individuals (e.g., farmers), management sectors, and ultimately the government. In regions with frequent TCs, the social–ecological systems are inevitably highly dynamic and rapid responses are fundamental to system resistance and resilience which in turn is key to maintaining structure and function of the social–ecological systems.
Cardiovascular Toxicity of Targeted Therapies for Cancer: An Overview of Systematic Reviews

Abstract Background Several targeted therapies for cancer have been associated with cardiovascular toxicity. The evidence for this association has not been synthesized systematically nor has the quality of evidence been considered. We synthesized systematic review evidence of cardiovascular toxicity of individual targeted agents. Methods We searched MEDLINE, Embase, and the Cochrane Database of Systematic Reviews for systematic reviews with meta-analyses of cardiovascular outcomes for individual agents published to May 2020. We selected reviews according to prespecified eligibility criteria (International Prospective Register of Systematic Reviews CRD42017080014). We classified evidence of cardiovascular toxicity as sufficient, probable, possible, or indeterminate for specific cardiovascular outcomes based on statistical significance, study quality, and size. Results From 113 systematic reviews, we found at least probable systematic review evidence of cardiovascular toxicity for 18 agents, including high- and all-grade hypertension for bevacizumab, ramucirumab, axitinib, cediranib, pazopanib, sorafenib, sunitinib, vandetanib, aflibercept, abiraterone, and enzalutamide, and all-grade hypertension for nintedanib; high- and all-grade arterial thromboembolism (includes cardiac and/or cerebral events) for bevacizumab and abiraterone, high-grade arterial thromboembolism for trastuzumab, and all-grade arterial thromboembolism for sorafenib and tamoxifen; high- and all-grade venous thromboembolism (VTE) for lenalidomide and thalidomide, high-grade VTE for cetuximab and panitumumab, and all-grade VTE for bevacizumab; high- and all-grade left ventricular ejection fraction decline or congestive heart failure for bevacizumab and trastuzumab, and all-grade left ventricular ejection fraction decline/congestive heart failure for pazopanib and sunitinib; and all-grade corrected QT interval prolongation for vandetanib. Conclusions Our review provides an accessible summary of the cardiovascular toxicity of targeted therapy to assist clinicians and patients when managing cardiovascular health.
Identification of larval fish in mangrove areas of Peninsular Malaysia using morphology and DNA barcoding methods

Summary The identification of larval fish has been an important morphological issue in marine biology due to the dramatic transformations that most species undergo from early larval stages to adulthood. Insufficient morphological diagnostic characters in larval fishes made it easy to misidentify them and a difficult process to key to genus and species level. The experiment aims to find out, by applying DNA barcoding, how consistent the morphological identifications can be among larval fish. Larval fish were mainly collected using plankton nets around mangrove areas in Pendas (Johor), Setiu (Terengganu), Pekan (Pahang) and Matang (Perak) Malaysia between April 2015 and October 2015. A total of 354 samples were morphologically identified, mostly to the family level and a few to the genus level. Larval fish ranged from 1.5 mm to 31 mm of total length, with the most abundant individuals being <3 mm. Among them, a total of 177 individuals were selected for DNA barcoding analyses. Molecular works involved polymerase chain reaction (PCR) and sequencing of mitochondrial Cytochrome c Oxidase I (COI) gene fragment (655 base pairs) methods. DNA barcoding enabled all samples to be identified down to species level. The overall genetic identities ranged from 91% to 100%. Morphological identification classified the specimens into 19 families and 11 genera while DNA barcoding identified them into 19 families 33 genera and 40 species. A comparison between the two methods showed a mismatched identification of 42.6% where the accuracy percentage for morphological identification was moderate for the family level (67.8%) but was low for genus level identification (30%). The DNA barcoding method also managed to successfully identify 86.4% of the samples up to their species level where morphological method has failed to do so. The most misidentified families in the study were Blenniidae, Sparidae, Apogonidae Ambassidae and Monachantidae while almost all samples from the family Gobiidae and Engraulidae were correctly identified to family level because of their distinct morphology. In conclusion, taxonomic studies of larval fish should continue using combination of both morphology and DNA barcoding methods. Morphological identification should be more conservative i.e., when in doubt, it is better to key only to family and not to the genus and species level. DNA barcoding is a better method for deeper taxonomic levels identification with the existence of robust sequence reference libraries and should be able to validate the accuracy of traditional larval fish identification.