Miracle-dz/UniFAR-FTUs huggingface dataset:
Does Divergence of Opinions make better minds? Evidence from Social Media

We investigate whether disagreement on StockTwits provides firm-specific information. Using supervised machine learning approaches and a novel dataset, we predict investors' recommendations and measure disagreement among investors on StockTwits. Our findings suggest that an increase in investors' disagreement results in a drop in return synchronicity. The negative impact of investors' disagreement on return synchronicity suggests higher inflows of firm-specific information. In line with this view, we find that disagreement improves price informativeness by increasing the price leads of earnings. Further empirical evidence suggests that the negative impact of disagreement on return synchronicity is more pronounced for firms with less transparent information environments and higher salience on StockTwits.
Medication Management at Home and Medication Adherence in Older Patients with Polypharmacy: In-Depth Interviews with Home Visits

Objectives: This study qualitatively explores the patients with polypharmacy medication management at home. Design: Qualitative study with in-depth interviews and home visits Setting: A semiurban area in the Pathum-Thani province, Thailand. Participants: We interviews 19 elderly patients aged [≥]60 years with polypharmacy at their houses and took photos of medication storage locations. Results: Of the 19 patients (mean age=69 years), nine reported good medication adherence. Two themes emerged: medication management at home and factors affecting medication adherence. Medication management at home comprised three subthemes: a medication storage system, a medication sorting system, and remaining medications. Some patients with medication nonadherence removed medications from blister packages. Other factors affecting medication adherence included knowledge, attitude, and lifestyles. All the patients had a positive attitude towards medication adherence; however, misunderstanding about medication administration prevented them from adhering to medications. Conclusion: The elderly patients managed medications at home differently. Medication nonadherence was common in those who removed medications from blister packages. Doctors and pharmacists should encourage the patients to use pillboxes or discourage patients from removing medications from blister packages.
Micropathology of the Internal Organs of Japanese Quails Naturally Infected with Eimeria tenella

Сoccidiosis is a protozoan disease caused by Eimeria bateri (E. bateri), Eimeria tsunodai (E. tsunodai), Eimeria uzura (E. uzura), Eimeria tenella (E. tenella), Eimeria necatrix (E. necatrix), and Eimeria acervulina (E. acervulina). The goal of the current study was to explore the micropathology of the duodenum, jejunum, caecum, liver, lung, spleen, kidney, adrenal gland of Japanese quails naturally infected with. E. tenella. The histopathological examination revealed that developmental E. tenella led to the damage of caecal, duodenal, and jejunal. Necrosis and desquamation of the integumentary epithelium, atrophy of crypts and folds, hemorrhages, lymphoid infiltration were confirmed in the mucous membrane of these intestines. The main changes observed in the parenchymal organs involved the fatty dystrophy of hepatocytes and lymphoid infiltration of parenchyma of the liver, stagnant hyperemia and edema of the lungs; granular dystrophy and necrosis of epithelial cells of the collecting ducts of the kidneys, venostasis of blood sinusoids of the spleen, hyperplasia of interrenal tissue, and dystrophia of suprarenal tissue of the adrenal gland. Morphometric studies have shown that pathological changes in the organs of quails infected with E. tenella led to a decrease in the thickness of the caecal mucosa, volume of the parabronchial lumen of the lung, and the number of renal corpuscles of the infected group, compared to the control group. The indicators of the interrenal-adrenal index of the adrenal glands, the number of clusters of lymphoid cells of the liver, and lymphoid nodules of the spleen increased. The received information could offer deep insights about pathogens in quails coccidiosis and can be used for planning therapeutic measures.
Effect of Addition of Tungsten Carbide on the Structural and Physical Properties of an Aluminum-Based System By Powder Method

The powder technology method was used for the purpose of making samples from the compound (Al-10%Al2O3-%WC), where the first support material was used alumina Al2O3 at a fixed rate of 10% and the second support material WC was in different proportions (0,5, 10,15,20) %, the three powders were grinded together for a period of two hours, then put into a mold and the process was pressed with a hydraulic press at 5 tons for a time of one minute. An English-origin oven was used and the sintering process was done for the samples at 560°C and for a time of only two hours. After that, compositional tests (XRD), physical (real and apparent density, real and apparent porosity) and mechanical (diagonal compressive strength) were performed on the sintered samples. As these tests gave encouraging results with almost distinctive characteristics at a ratio of mixing of 20% WC and thermal sintering of 560°C, as the bulk density was within the limits of 5.51 g/cm3 while the real density was 4.9 g/cm3, while the minimum apparent porosity was 8.83% and the porosity. The real one is 11.76%, while the diagonal compressive strength is 45.33MPa. As for the structural results of the X-ray diffraction after the sintering process, it showed the emergence of a new phase of the tertiary metal oxide (WO3) and the (Triclinic) phase, as well as the emergence of tungsten carbide in the cubic phase.
Anti-quorum sensing effect of streptococcus agalatiaceae by Zinc Oxide, Copper Oxide, and Titanium Oxide nanoparticles

Quroum sensing system found in many species of bacteria, including Streptococcus agalactiae that use to regulate many virulence and pathogenicity characteristics. So, this study achieved to detect the inhibitory effect of (CuO, ZnO, TiO2) nanoparticles on quorum sensing of Streptococcus agalactiae. The bacterial isolates of Streptococcus agalactiae were obtained from vaginal and rectal swabs from pregnant women who visited maternity and children hospital in Al-Diwaniyah city from 7/2018 to 4/2019. Three metal oxides nanoparticles (CuO, ZnO, TiO) were used which was examined using a scanning electron microscope and then three different concentrations were prepared (100,250,500) μg\ml to study its effectiveness against quorum sensing. The nanoparticles showed their effectiveness in inhibiting the quorum sensing of Streptococcus agalactiae through the formation of a clear inhibition zone around the wells. Copper oxide nanoparticles showed high efficiency in inhibition of the quorum sensing with a diameter of (35) mm. Also, zinc oxide nanoparticles showed efficacy against the quorum sensing with diameter (27) mm, while the less inhibition effect appeared with the use of titanium oxide, where the diameter of inhibition was (20) mm. The results of the study showed the efficiency of nano-oxides (TiO2, ZnO, CuO) in inhibiting the quroum sensing of S.agalactiae bacteria, and copper oxide was the most efficient among them. So, there is need to further studies to detect the effect of nanoparticles on quorum sensing and virulence factors of other bacteria.
Hydroxychloroquine's Influence on Hypoxic and Hypokalemic ventricle: An Insilico Perspective

Hydroxychloroquine (HCQ) has been widely used, irrespective of pre reported cardiotoxicity. This demands further investigation on the mechanisms of HCQ interaction under hypoxia without and with a pro-arrhythmic comor-bidity like hypokalemia in the ventricular tissue as well as its effects when excited with premature beats (PBs) to understand the possibility of arrhythmic occurrence. This is made possible by configuring a 2D transmural anisotropic ventricular tissue model consisting of endocardial, mid-myocardial and epicardial myocytes for mild and severe hypoxia, hypokalemia and HCQ conditions. Results show that along with a QT interval reduction, low amplitude or T-wave inversion is observed in mild and severe hypoxia conditions respectively. No significant adverse effect of HCQ is observed in both cases. Under hypokalemia, mild hypoxia creates notched T-waves. Including HCQ has the effect of increasing the QT interval and T-peak. In presence of PBs, arrhythmia is generated only in presence of hypokalemia. Further, severe hypoxia causes inverted T-waves and a shortened QT-interval in hypokalemic comor-bid configuration. In presence of PBs, reentry is created only on addition of hypokalemia. When treated with HCQ, no notable changes occurred. This in-silico ventricular model indicates that HCQ treatment has no significant adverse effect in presence of hypokalemia and hypoxia, except in the combination of mild hypoxia with hypokalemia condition where it initiated a re-entrant arrhythmia pattern. These results could help guide treatment with HCQ.
The emission reduction potential of electric transport modes in Finland

The transportation sector has become the fastest growing source of greenhouse gas (GHG) emissions. One solution to mitigate the impacts is a shift towards electric modes. Where previous studies have only focused on the replacement of individual modes, our study presents a more holistic approach by comparing land-based, water-based and airborne transportation modes. We study the GHG emission reduction potentials of electric cars, buses, trains, ferries and aircraft in comparison to existing modes on 34 routes within Finland and across the Baltic Sea to Sweden and Estonia. By comparing the GHG emissions in carbon dioxide equivalents (CO2-eq) per passenger kilometer for each mode, we also consider the emissions generated from battery production as well as the differences in the energy mix from electricity production of the three studied countries. In addition to CO2-eq emissions per passenger kilometer, we also take real door-to-door travel times into account. Our study found that electric transportation modes possess great potential for emissions reduction. Nevertheless, depending on the energy mix used for electricity production, the emissions of electric transportation modes can exceed those of existing modes significantly. In addition, the emissions generated by battery production can have a significant share of the total emissions and should therefore always be considered. Finally, while also taking into account the door-to-door travel times, our study identified the great potential of electric aircraft to provide a less carbon intensive transportation option paired with short travel times starting on routes beyond 300 km where no high-speed rail exists as well as on routes across the water.
Design and implementation of multiplexed amplicon sequencing panels to serve genomic epidemiology of infectious disease: A malaria case study

Multiplexed PCR amplicon sequencing (AmpSeq) is an increasingly popular application for cost‐effective monitoring of threatened species and managed wildlife populations, and shows strong potential for the genomic epidemiology of infectious disease. AmpSeq data from infectious microbes can inform disease control in multiple ways, such as by measuring drug resistance marker prevalence, distinguishing imported from local cases, and determining the effectiveness of therapeutics. We describe the design and comparative evaluation of two new AmpSeq assays for Plasmodium falciparum malaria parasites: a four‐locus panel (“4CAST”) composed of highly diverse antigens, and a 129‐locus panel (“AMPLseq”) composed of drug resistance markers, highly diverse loci for inferring relatedness, and a locus to detect Plasmodium vivax co‐infection. We explore the performance of each panel in various public health use cases with in silico simulations as well as empirical experiments. The 4CAST panel appears highly suitable for evaluating the number of distinct parasite strains within samples (complexity of infection), showing strong performance across a wide range of parasitaemia levels without a DNA pre‐amplification step. For relatedness inference, the larger AMPLseq panel performs similarly to two existing panels of comparable size, despite differences in the data and approach used for designing each panel. Finally, we describe an R package (paneljudge) that facilitates the design and comparative evaluation of genetic panels for relatedness estimation, and we provide general guidance on the design and implementation of AmpSeq panels for the genomic epidemiology of infectious disease.
Corrections to universal Rényi entropy in quasiparticle excited states of quantum chains

We investigate the energy eigenstate Rényi entropy of generic bipartition in the fermionic, bosonic, and spin-1/2 XY chains. When the gap of the theory is large or all the momenta of the excited quasiparticles are large, the Rényi entropy takes a universal form, which is independent of the model, the quasiparticle momenta, and the subsystem connectedness. We calculate analytically the Rényi entropy in the extremely gapped limit and find different additional contributions to the universal Rényi entropy in various models. The corrections to the universal Rényi entropy cannot be neglected when the momentum differences of the excited quasiparticles are small. The Rényi entropy derived in the extremely gapped limit is still valid in the slightly gapped and even critical chains as long as all the momenta of the excited quasiparticles are large. In the case of double interval in the XY chain we find new universal results and their corrections. We call the result universal even though it is only valid for double interval in the spin-1/2 XY chain. In the case of the bosonic chain in the extremely massive limit we find analytically a novel formula for the Rényi entropy written as the permanent of a certain matrix. We support all of our analytical results with numerical calculations.
A procedure to redesign a comparable blade structure of a two-bladed turbine based on a three-bladed reference

Two-bladed turbines might be an alternative for future offshore wind turbine installations due to the promising opportunity to be more economical compared to three-bladed turbines. Looking at the rotor blades, two-bladed turbines with a comparable design either rotate 22.5% faster or have up to 50% increased chord lengths. The latter result in a significantly higher second moment of area, which enables rotor mass savings and thus fewer costs while withstanding ~50 % higher flapwise loads per blade. Unfortunately, such a design could also cause buckling issues. Increasing the design tip speed reduces stability issues but lowers the rotor mass savings. Consequently, the challenging task is to find an optimal compromise between preventing buckling and saving rotor mass, and thus to ensure a fair comparison of two- and three-bladed turbines’ blades. To overcome this challenge, a procedure for redesigning a comparable blade structure is introduced. The procedure is exemplarily demonstrated for large 20 MW offshore wind turbines. Compared to the three-bladed reference, the overall rotor mass reduction of the two-bladed turbine is 13.5 % for the most beneficial compromise detected. Simultaneously, the blades showing good accordance with the reference concerning static stresses and buckling characteristics under their respective loads.
Numerical findings on crucial viral pathogens in Rainbow trout (Onchorhynchus mykiss) farms of northern Iran

Viral hemorrhagic septicemia virus (VHSV), Infectious hematopoietic necrosis virus (IHNV), and infectious pancreatic necrosis virus (IPNV) are documented as the most considerable viral pathogens in Rainbow trout (Onchorhynchus mykiss). This study aimed to evaluate the frequency of these pathogens in 65 farms with suspected clinical signs in northern Iran from March 2016 to February 2018. Logistic regression analysis used to assess the effect of several determinant factors on the occurrence of these pathogens. In total, 19 (29.23%) farms were positive by a reverse transcription-polymerase chain reaction (RTPCR). The frequency of VHSV, IHNV, and IPNV was reported 18.5%, 6.2%, and 4.61%, respectively. The most affected farms (78.95%) used river water. Furthermore, our results revealed that using river water raised the chances of viral disease by 5 times (OR = 5.02; P = 0.01). Correspondence M Khosravi, Department of Pathobiology, Faculty of Veterinary Medicine, Amol University of Special Modern Technologies, Amol, Iran (e-mail: mojtaba.kh.dvm@gmail.com). Thus, using river water was a risk factor for the occurrence of viral pathogens. From four weight groups (A to D); fishes in groups A (fish < 1 gr) and B (1 to 20 gr) were more affected but not statistically significant (P>0.05). This study has provided insight into the frequency of these targeted viruses. Collectively, establishing routine rapid diagnostic programs and setting up basic educational practices can be valuable to design the prevention and control strategies.
Spectroscopic Study for Effect of Heating Temperatures on the Black Seed Oil

The existing investigation explains the effect of temperature on black seed oil, what are the changes that occur to the oil when it is heated to a temperature higher than (100 C°), and what is the effect of that change on human health when using this oil.it was heated to several temperatures ranging from (30 C°) to (150 C°). The absorbance of the samples was measured before and after heating using the UFI device. The intensity was also measured by irradiating each sample using a red laser. It has been found that when the oil is heated to a temperature higher than 100 C°, a change occurs in the composition of the oil with a change in its physical properties such as color, smell, taste … etc. and the formation of another compound, and the new compound may be toxic.
Synthesis, characterization, and spectroscopic properties of new azo dyes derived from Sulfamerazine based on β- diketones and azo-metal (II) complexes

In the present study, two new azo dyes from 4-amino-N-(4-methyl-2- pyrimidinyl(benzenesulfonamide) with acetylacetone( L1) and benzoyl acetone(L2) were synthesized. The characterization of dyes has been described by IR,C.H. N,1H-NMR, and TGA. The reaction of these new dyes with acetate salts of copper(II) and nickel(II) in molar ratios of 1:2 was carried out to produce azo metal(II) complexes. Theanalytical data show that the metal to ligand ratio [M:L] in all complexes is (1:2). The spectral and analytical data revealed that this ligand behaves as a bidentate chelating. The thermal behavior of these compounds was investigated based on thermogravimetric (TGA) analyse. Thermal decomposition of these compounds is multi-stage processes.
Response of Three Bread Wheat Cultivars to Foliar Spray by Some Micro- Nutrients Nano- Particles

A field experiment was carried out during 2017/18 and 2018/19 seasons at the Agronomy Department Experimental Farm, Agriculture Faculty, Assiut University, to study the effect of foliar spray by some Nano micro-nutrients on production of three bread wheat cultivars. The experiment was laid out in randomized complete block design (RCBD) using strip plot arrangement with three replications. Foliar spray with tap water (solvent as a control) and Foliar spray with Fe, Mn, Zn, Fe+Mn, Fe+Zn, Mn+Zn and Fe+Mn+Zn in Nano form at 200 ppm were allocated horizontally, while bread wheat cultivars (Sids-1, Sids-12 and Gemmeaza-11) were arranged vertically. The obtained results show that the foliar spray treatment by some micro-nutrients Nano-particles had a significant effect on plant height, kernels number spike, 1000 kernel weight, kernel weight spike and grain yield in both seasons. Thus, wheat plants which were sprayed by Fe+Mn+Zn produced the highest mean values of the most previous traits. Furthermore the studied cultivars had a significant effect on all studied traits. In addition, Gemmeaza-11 cultivar produced the highest mean values of most studied traits in the two growing seasons. Here too, the interaction between some micro-nutrients Nano-particles and bread wheat cultivars had a highly significant (P ≤ 0.01) and significant (P ≤ 0.05) influence on grain yield in the first and second seasons respectively. Thus, the highest mean values of grain yield (26.80 and 26.95 ardab fed. in the tow respective seasons) were obtained from Gemmeaza11 cultivar which was sprayed by Fe+Mn+Zn Nano-particles in both seasons.
Central oxidative stress and early vocational outcomes in first episode psychosis: A 7-Tesla Magnetic Resonance Spectroscopy study of glutathione

Following the first episode of psychosis, some patients develop poor social and occupational outcomes, while others display a pattern of preserved functioning. Several lines of evidence from preclinical, genetic and biochemical studies suggest a role for high oxidative stress in poor functional outcomes. The measurement of intracortical glutathione (GSH) using magnetic resonance spectroscopy (MRS) provides an opportunity to investigate the relationship between central antioxidant tone and functional outcomes at the time of first episode psychosis (FEP). A body of epidemiological studies indicates better functional outcomes in patients at early stages of schizophrenia compared to patients at a chronic, established phase of illness. We scanned 57 patients with FEP and 30 matched healthy controls and estimated GSH resonance using 7-Tesla MRS. We minimised the confounding effects of illness chronicity, long-term treatment exposure and metabolic complications by recruiting patients with <2 weeks of lifetime antipsychotic exposure on average and followed up this cohort for the next 1 year to determine functional outcomes. Patients with FEP who achieved employment/education or training status (EET) in the first year, had higher GSH at the baseline than healthy controls. Social and occupational functioning assessment scale (SOFAS) scores were also significantly higher in patients with higher GSH levels at the outset, after adjusting for various confounds including baseline SOFAS. Patients who were not in employment, education or training (NEET) did not differ from healthy subjects in their GSH levels. Our observations support a key role for the central antioxidant tone in the functional outcomes of early psychosis.
Are Private Equity Funds Superior Real Estate Investors? Evidence from the Hotel Industry

We dissect the performance of private equity (PE) investors in commercial real estate. We observe acquisitions, dispositions, and granular performance data for several thousand U.S. hotels. Investments by PEs specializing in the hospitality industry lead to more substantial operating efficiency gains than those by their generalist counterparts. Specialist PEs also improve bottom-line profits—although at the expense of lower guest satisfaction—and realize significantly higher capital gains than other types of investors. By contrast, generalist PE funds’ main comparative advantage in real estate markets may be their access to cheap financing.
Scale and Performance in Active Management are Not Negatively Related

We revisit the nature of returns to scale following Pástor, Stambaugh, and Taylor (2015). Using replicated versions of their domestic equity fund sample, we confirm their negative and significant relation between industry scale and performance. However, upon closer examination we find the diseconomies of scale at the industry level result is an artifact of data errors that comprise less than 0.05% of the sample―168 out of 332,516 observations―that occurred most often in the year 2000. We are unable to find industry level diseconomies of scale in the post 2001 era. A major source of these errors is the incorrect use of Morningstar’s current performance benchmarks to measure historical return performance. We confirm the non-result findings using Fama-French three-factor adjusted returns, which are not subject to benchmarking errors.