Miracle-dz/UniFAR-FTUs huggingface dataset:
Students’ Perceptions of a Token Economy in an Undergraduate Science Flipped Class-Room

Abstract: Engaging students in higher education is a critical aspect of student learning (Barkley, 2009; Coates, 2005). Flipped classroom are being reported in the literature as a means to engage students in the learning process, compared to traditional lectures (O’Flaherty & Phillips, 2015). However, flipped classrooms are difficult to implement without students taking an active role in the learning process (Long, Cummins, & Waugh, 2017). Token economies, which are widely used in primary school settings but rarely reported in higher educational settings, enable instructors to provide students with rewards to reinforce targeted student behaviors (Hine, Ardoin, & Call, 2018; McClurg & Morris, 2014), and may be useful in the flipped classroom model. In this mixed methods case study, the researchers collected survey and focus group data from 48 undergraduate students who attended a science course with a token economy to determine the students’ perceptions of the token economy and satisfaction of the novel rewards offered. The findings indicated that over 90% of the students participated in the token economy and 74% of students indicated that the reward system reinforced the student behaviors necessary for an effective flipped classroom. The students also discussed how the token economy provided motivation and additional opportunities to master course content, decreased student anxiety, and enhanced the student-teacher relationship.
Differences in the MRI Signature and ADC Values of Diffuse Midline Gliomas with H3 K27M Mutation Compared to Midline Glioblastomas

Simple Summary Diffuse midline glioma is a rare distinct brain tumor entity introduced by the recent WHO (Lyon, France) brain tumor classification. MR imaging is important for detection as well as characterization of these midline tumors, which are located within the brainstem, since neurosurgical tissue sampling in these locations can be challenging. We therefore searched for possible differences in the MRI pattern between diffuse midline gliomas and midline glioblastomas, both regarded as grade IV entities. Abstract We conducted a two-center retrospective survey on standard MRI features including apparent diffusion coefficient mapping (ADC) of diffuse midline gliomas H3 K27M-mutant (DMG) compared to midline glioblastomas H3 K27M-wildtype (midGBM-H3wt). We identified 39 intracranial DMG and 18 midGBM-H3wt tumors. Samples were microscopically re-evaluated for microvascular proliferations and necrosis. Image analysis focused on location, peritumoral edema, degree of contrast enhancement and DWI features. Within DMG, MRI features between tumors with or without histomorphological GBM features were compared. DMG occurred in 15/39 samples from the thalamus (38%), in 23/39 samples from the brainstem (59%) and in 1/39 tumors involving primarily the cerebellum (2%). Edema was present in 3/39 DMG cases (8%) versus 78% in the control (midGBM-H3wt) group (p < 0.001). Contrast enhancement at the tumor rim was detected in 17/39 DMG (44%) versus 67% in control (p = 0.155), and necrosis in 24/39 (62%) versus 89% in control (p = 0.060). Strong contrast enhancement was observed in 15/39 DMG (38%) versus 56% in control (p = 0.262). Apparent diffusion coefficient (ADC) histogram analysis showed significantly higher skewness and kurtosis values in the DMG group compared to the controls (p = 0.0016/p = 0.002). Minimum relative ADC (rADC) values, as well as the 10th and 25th rADC-percentiles, were lower in DMGs with GBM features within the DMG group (p < 0.001/p = 0.012/p = 0.027). In conclusion, DMG cases exhibited markedly less edema than midGBM-H3wt, even if histomorphological malignancy was present. Histologically malignant DMGs and midGBM-H3wt more often displayed strong enhancement, as well as rim enhancement, than DMGs without histomorphological malignancy. DMGs showed higher skewness and kurtosis values on ADC-histogram analysis compared to midGBM-H3wt. Lower minimum rADC values in DMGs indicated malignant histomorphological features, likely representing a more complex tissue microstructure.
The impact of preoperative neurological symptom severity on postoperative outcomes in cervical spondylotic myelopathy

Study Design: The study design is a retrospective cohort study. Objective: To compare patient-reported outcomes between patients with mild versus moderate-to-severe myelopathy following surgery for cervical spondylotic myelopathy (CSM). Summary of Background Data: Recent studies have demonstrated that decompression for CSM leads to improved quality of life when measured by patient-reported outcomes. However, it is unknown if preoperative myelopathy classification is predictive of superior postoperative improvements. Materials and Methods: A retrospective review of patients treated surgically for CSM at a single institution from 2014 to 2015 was performed. Preoperative myelopathy severity was classified according to the modified Japanese Orthopaedic Association (mJOA) scale as either mild (≥15) or moderate-to-severe (<15). Other outcomes included neck disability index (NDI), 12-item short-form survey (SF-12), and visual analog scale (VAS) for arm and neck pain. Differences in outcomes were tested by linear mixed-effects models followed by pairwise comparisons using least square means. Multiple linear regression determined whether any baseline outcomes or demographics predicted postoperative mJOA. Results: There were 67 patients with mild and 50 patients with moderate-to-severe myelopathy. Preoperatively, patients with moderate-to-severe myelopathy reported significantly worse outcomes compared to the mild group for NDI, Physical Component Score (PCS-12), and VAS arm (P = 0.031). While both groups experienced improvements in NDI, PCS-12, VAS Arm and Neck after surgery, only the moderate-to-severe patients achieved improved mJOA (+3.1 points, P < 0.001). However, mJOA was significantly worse in the moderate-to-severe when compared to the mild group postoperatively (-1.2 points, P = 0.017). Both younger age (P = 0.017, β-coefficient = −0.05) and higher preoperative mJOA (P < 0.001, β-coefficient = 0.37) predicted higher postoperative mJOA. Conclusions: Although patients with moderate-to-severe myelopathy improved for all outcomes, they did not achieve normal absolute neurological function, indicating potential irreversible spinal cord changes. Early surgical intervention should be considered in patients with mild myelopathy if they seek to prevent progressive neurological decline over time.
The Politics of White Identity and Settlers’ Indigenous Resentment in Canada

Abstract This article introduces White identity as an understudied concept in Canadian politics and compares how White settlers’ ingroup attachments and their outgroup attitudes—specifically, White settlers’ anti-Indigenous attitudes—shape Canadian politics. We find that White identity is associated with greater support for government spending on policies that disproportionately benefit White Canadians, such as pensions, whereas Indigenous resentment is associated with greater opposition toward government spending on policies that are often perceived as disproportionately benefiting Indigenous peoples, such as welfare. In Canada outside Quebec, both White identity and anti-Indigenous attitudes are associated with voting Conservative. In Quebec, White identity mobilizes support for the Bloc Québécois, while White settlers’ negative attitudes toward Indigenous peoples are not associated with vote choice.
FERTILITY OUTCOMES AFTER MEDICAL AND SURGICAL MANAGEMENT OF TUBAL ECTOPIC PREGNANCY

SUMMARY The objective was to investigate whether the method of treatment (surgical or medical) affects achieving a new pregnancy, as well as the time to and prognosis of the new pregnancy, in women with ectopic pregnancy (EP). Information on patients treated in our hospital between 2013 and 2014 for EP was retrieved from the computerized patient records. Data on whether these patients achieved pregnancy after EP treatment, time from treatment to new pregnancy, and prognosis of pregnancy were collected by phone interviews. A total of 101 women were analyzed. In addition to descriptive analysis, the χ2-test and Kruskal Wallis test were used to compare the groups. A new pregnancy was present in 84 (83.2%) of the women after EP treatment. There was no significant difference among the women having undergone medical treatment (methotrexate), surgical treatment, medical treatment followed by surgical treatment, or observational management approach in terms of achieving a new pregnancy after treatment and time to and prognosis of the new pregnancy. The study could not determine which treatment method would be superior in women with EP and in planning future pregnancy, but concluded that close clinical and laboratory monitoring is appropriate before deciding on aggressive interventions.
Development of Equivalent Circuit Models of Permanent Magnet Synchronous Motors Considering Core Loss

Permanent magnet synchronous motor (PMSM) possesses the advantages of low power loss, high power density and high torque density and, hence, has achieved broad applications in both industrial drives and home appliances. With the increasing demands for high power density, the PMSM often operates at high speed and high frequency, leading to high power loss and temperature rise. Consequently, proper consideration of power loss, including the core loss, has attracted much attention for the modelling, designing, controlling and optimizing of PMSMs. However, the widely used equivalent circuit model, capable of providing good analysis results with fast calculation, often ignores the core loss, which may lead to unsatisfactory motor performance. This paper aims to investigate the development of equivalent circuit models, with predictable core loss for PMSMs, and proposes novel equivalent circuit models, which improve the core loss prediction accuracy in the load conditions. Some thoughts about the further improvement of the models are proposed and discussed.
Respiratory Syncytial Virus Infection Modeled in Aging Cotton Rats (Sigmodon hispidus) and Mice (Mus musculus)

Serious infection with respiratory syncytial virus (RSV) is associated with high risk in infants, children, and elderly. There is currently no approved vaccine against RSV infection, and the only available prevention is immunoprophylaxis utilized in high-risk infants, leaving the elderly without many options. In the elderly, the chronic low-grade inflammatory state of the body can play a significant role during infection. The cotton rat and mouse have emerged as the preferred small animal models to study RSV infection in the elderly. These animal models of aging have shown an age-dependent time course for clearance of virus correlating with a significantly diminished cytotoxic T lymphocyte and humoral immune response in old animals compared to adult animals. In addition, protection through vaccination is reduced in aging rodents. These results mirror the findings in humans. In mice and cotton rats, treatment with ibuprofen, a nonselective nonsteroidal anti-inflammatory drug (NSAID), to decrease the chronic low-grade inflammation of the elderly immune system has proven successful in restoring the function of cytotoxic lymphocytes. While more research is required, these treatment types promise a beneficial effect in addition to a putative vaccine. Choosing an appropriate animal model to study RSV infection in the aging immune system is essential to benefit the growing population of elderly in the world. This review focuses on the current research of RSV infection in the cotton rat and mouse as model systems for an aging immune system.
SARS-CoV-2 Vaccination Coverage and Key Public Health Indicators May Explain Disparities in COVID-19 Country-Specific Case Fatality Rate Within European Economic Area

Aim To investigate the reasons for disparity regarding the country-specific COVID-19-related case fatality rate (CFR) within the 30 countries of the European Economic Area (EEA). Materials and methods Data regarding population, area, COVID-19-associated infections/deaths, vaccination, life expectancy, elderly population, infant mortality, gender disparity, urbanization, gross domestic product (GDP), income per capita, health spending per capita, physicians, nursing personnel, hospital beds, ICU beds, hypertension, diabetes, obesity, and smoking from all EEA countries were collected from official sources on January 16, 2022. Correlation coefficients were computed, and optimal scaling using ridge regression was used to reach the most parsimonious multivariate model assessing any potential independent correlation of public health parameters with COVID-19 CFR. Results COVID-19 CFR ranges from 0.1% (Iceland) to 4.0% (Bulgaria). All parameters but population density, GDP, total health spending (% of GDP), ICU beds, diabetes, and obesity were correlated with COVID-19 CFR. In the most parsimonious multivariate model, elderly population rate (P = 0.018), males/total ratio (P = 0.013), nurses/hospital beds (P = 0.001), physicians/hospital beds (P = 0.026), public health spending (P = 0.013), smoking rate (P = 0.013), and unvaccinated population rate (P = 0.00005) were demonstrated to present independent correlation with COVID-19 CFR. In detail, the COVID-19 CFR is estimated to increase by 1.24 times in countries with vaccination rate of <0.34, 1.11 times in countries with an elderly population rate of ≥0.20, 1.14 times in countries with male ratio values ≥0.493, 1.12 times in countries spending <2,000$ annually per capita for public health, 1.14 and 1.10 times in countries with <2.30 nurses and <0.88 physicians per hospital bed, respectively, and 1.12 in countries with smoking ratio ≥0.22, while holding all other independent variables of the model constant. Conclusion COVID-19 CFR varies substantially among EEA countries and is independently linked with low vaccination rates, increased elderly population rate, diminished public health spending per capita, insufficient physicians and nursing personnel per hospital bed, and prevalent smoking habits. Therefore, public health authorities are awaited to consider these parameters in prioritizing actions to manage the SARS-CoV-2 pandemic.
Isolation, Characterization, and Genomic Analysis of Three Novel E. coli Bacteriophages That Effectively Infect E. coli O18

Escherichia coli (E. coli) is one of the most common pathogenic bacteria worldwide. Avian pathogenic E. coli (APEC) causes severe systemic disease in poultry (Colibacillosis), and accordingly, has an extreme risk to the poultry industry and public health worldwide. Due to the increased rate of multi-drug resistance among these bacteria, it is necessary to find an alternative therapy to antibiotics to treat such infections. Bacteriophages are considered one of the best solutions. This study aimed to isolate, characterize, and evaluate the potential use of isolated bacteriophages to control E. coli infections in poultry. Three novel phages against E. coli O18 were isolated from sewage water and characterized in vitro. The genome size of the three phages was estimated to be 44,776 bp, and the electron microscopic analysis showed that they belonged to the Siphoviridae family, in the order Caudovirales. Phages showed good tolerance to a broad range of pH and temperature. The complete genomes of three phages were sequenced and deposited into the GenBank database. The closely related published genomes of Escherichia phages were identified using BLASTn alignment and phylogenetic trees. The prediction of the open reading frames (ORFs) identified protein-coding genes that are responsible for functions that have been assigned such as cell lysis proteins, DNA packaging proteins, structural proteins, and DNA replication/transcription/repair proteins.
Fixed-Time Neural Control of Robot Manipulator With Global Stability and Guaranteed Transient Performance

Nowadays, due to many limitations in reality, the optimization of tracking precision and convergence time has attracted the attention of researchers in robotics community. In this article, a fixed-time adaptive neural network (NN) controller is proposed for unknown robot manipulators. A switching mechanism is integrated into the control design such that the semiglobal stability of the conventional NN control systems can be extended to global stability. The time-varying barrier Lyapunov function and the fixed-time control technique are incorporated into the controller design to guarantee the prescribed motion constraints and the fixed-time convergence simultaneously. Compared with some existing fixed-time NN control algorithms, the assumption that NN weight should be upper bounded can be relaxed in our work. Finally, the simulation and experiment studies are respectively carried out based on an unknown 2-degree of freedom robot and a Baxter robot to demonstrate the effectiveness and superiority of the proposed control scheme.
Genomics‐based higher classification of the species‐rich hairstreaks (Lepidoptera: Lycaenidae: Eumaeini)

We propose a higher classification of the lycaenid hairstreak tribe Eumaeini – one of the youngest and most species‐rich butterfly tribes – based on autosome, Lepidopteran Z sex chromosome and mitochondrial protein‐coding genes. The subtribe Neolycaenina Korb is a synonym of Callophryidina Tutt and subtribe Tmolusina Bálint is a synonym of Strephonotina K. Johnson, Austin, Le Crom, & Salazar. Proposed names are Rhammina Prieto & Busby, new subtribe; Timaetina Busby & Prieto, new subtribe; Atlidina Martins & Duarte, new subtribe; Evenina Faynel & Grishin, new subtribe; Jantheclina Robbins & Faynel, new subtribe; Paiwarriina Lamas & Robbins, new subtribe; Cupatheclina Lamas & Grishin, new subtribe; Parrhasiina Busby & Robbins, new subtribe; Ipideclina Martins & Grishin, new subtribe; and Trichonidina Duarte & Faynel, new subtribe. Phylogenetic results from the autosome and Z sex chromosome analyses are similar. Future analyses of datasets with hundreds of terminal taxa may be more practical time‐wise by focussing on the smaller number of sex chromosome sequences (2.6% of nuclear protein‐coding sequences). The phylogenetic classification and biological summaries for each subtribe suggest that a variety of factors affected Eumaeini diversification. About a dozen kinds of male secondary sexual organs with frequent evolutionary gains and losses occur in Atlidina, Evenina and Jantheclina (141 species combined). Females have been shown to use these organs to discriminate between conspecific and nonconspecific males, facilitating sympatry among close relatives. Eumaeina, Rhammina and Timaetina (140 species combined) are overwhelmingly montane with some evidence for a higher incidence of sympatric diversification. Seven Neotropical lineages in five subtribes invaded the temperate parts of the Nearctic Region with a diversification increase in the Callophryidina (262 species). North American Satyrium and Callophrys then invaded the Palearctic at least once each, with a major species‐richness increase in Satyrium. The evolution of litter‐feeding detritivores within Calycopidina (172 species) resulted in an increase in diversification rate compared with its flower‐feeding sister lineage. Atlidina, Strephonotina, Parrhasiina and Strymonina (562 species combined) each contain a mixture of genera that specialize on one or two caterpillar food plant families and genera that are polyphagous. These would be appropriate subtribes to assess how the breadth of caterpillar food plants and the frequency of host shifts affected diversification.
Anisakis, Something Is Moving inside the Fish

The first case of human infection by a species of the Anisakidae family was reported more than 60 years ago. Over the last 20 years, Anisakis has become a highly studied parasite, not only for its parasitism, but also for its role as an inducer of allergic reactions. Several studies have indicated that the pathological changes occurring within the gastrointestinal tract during infection with Anisakis simplex are the combined result of the direct action of the larvae invading the tissue and the complex interaction between the host’s immune system and the parasite. Although the most commonly described pathologies are digestive, urticaria/angioedema and anaphylaxis, occupational asthma and arthritis have been seldom described. This paper is a narrative of the immune-mediated reaction induced by this parasite over the course of the last two decades.
Examining the effect of transcranial direct current stimulation on the dominant motor cortex in the indirect measurement of physical ability

Background: The effects of transcranial direct current stimulation (tDCS) on specific sports skills have received extensive attention, however, it is difficult to accurately determine its effect on physical performance due to the complexity of the tasks. The objective of this study was to investigate the effects of uni-hemispheric anodal tDCS of the motor cortex (M1) on the indirect measurement of physical ability in healthy men. Methods: Thirteen healthy, right-leg-dominant men aged between 21 and 32 years (26.53± 2.73 years) participated in two different experimental conditions in a randomized, single-blinded crossover design: anodal stimulation (a-tDCS) and sham-tDCS (2mA for 20 minutes targeting the left M1 contralateral to dominant leg). Before and immediately after the tDCS stimulation, participants completed the standing long jump (SLJ) and sidestep test (SST), and their blood pressure and heart rate were checked for the safety of tDCS application. Results: No significant difference was observed between a-tDCS and sham-tDCS (F(1,24) = 0.02, p = 0.86, η p = 0.001) on SLJ. Also, no significant changes in SLJ were observed between preand post-stimulation sessions for both conditions (F(1,24) = 1.18, p = 0.28, η p = 0.047). Similarly, SST scores were not significantly different from a-tDCS and sham-tDCS condition (F(1,24) = 0.57, p = 0.45, η p = 0.024). Significant changes in SST were not observed throughout the experiment sessions for both stimulation conditions (F(1,24) = 0.12, p = 0.73, η p = 0.005). Conclusions: The uni-hemispheric a-tDCS applied over the M1 for 20 minutes may not be a valuable tool to obtain the physical performance benefits from the tasks that require bilateral lower limb power output, such as SLJ and SST.