Miracle-dz/UniFAR-FTUs huggingface dataset:
Antibody Mediated Intercommunication of Germinal Centers

Antibody diversification and selection of B cells occur in dynamic structures called germinal centers (GCs). Passively administered soluble antibodies regulate the GC response by masking the antigen displayed on follicular dendritic cells (FDCs). This suggests that GCs might intercommunicate via naturally produced soluble antibodies, but the role of such GC–GC interactions is unknown. In this study, we performed in silico simulations of interacting GCs and predicted that intense interactions by soluble antibodies limit the magnitude and lifetime of GC responses. With asynchronous GC onset, we observed a higher inhibition of late formed GCs compared to early ones. We also predicted that GC–GC interactions can lead to a bias in the epitope recognition even in the presence of equally dominant epitopes due to differences in founder cell composition or initiation timing of GCs. We show that there exists an optimal range for GC–GC interaction strength that facilitates the affinity maturation towards an incoming antigenic variant during an ongoing GC reaction. These findings suggest that GC–GC interactions might be a contributing factor to the unexplained variability seen among individual GCs and a critical factor in the modulation of GC response to antigenic variants during viral infections.
Exploring the roles of self-determined motivation and perceived organizational support in organizational change

PurposeThe primary purpose of this study is not only to examine the connections between self-determined motivation, attitudes toward change and participation in change, but also to explore the moderating impact of perceived organizational support on organizational change, and the mediating role of attitudes toward change in the link between perceived competence and participation in change.Design/methodology/approachThe data were collected from one semiconductor manufacturing company (study 1) and one logistics service company (study 2). Employees who experienced organizational change before were invited to finish the survey. The partial least squares-structural equation modelling (PLS-SEM) technique and SPSS PROCESS (model 14) were utilized to analyze the data.FindingsThe study findings indicated that the perceived autonomy and relatedness were positively connected with perceived competence, which in turn would lead to better attitude toward change. Additionally, it was found that the perceived competence and attitude toward change would positively predict participation in change. More importantly, perceived organizational support would reinforce the positive relationship between attitude toward change and participation in change.Originality/valueAlthough there are many organizational change reports, relatively little attention has been paid not only to the mediating role of attitudes toward change in the implication of organizational change but also to the moderating impact of perceived organizational support on the final success of organizational change.
Family Herpesviridae and neuroinfections: current status and research in progress

This article addresses the relationship between human herpesviruses (HHVs) and neuroinfections. Alphaherpesviruses, betaherpesviruses and gammaherpesviruses are neurotropic viruses that establish latency and exhibit reactivation capacity. Encephalitis and meningitis are common in cases of HHV. The condition promoted by HHV infection is a purported trigger for certain neurodegenerative diseases. Ongoing studies have identified an association between HSV-1 and the occurrence of Alzheimer’s disease, multiple sclerosis and infections by HHV-6 and Epstein-Barr virus. In this review, we highlight the importance of research investigating the role of herpesviruses in the pathogenesis of diseases that affect the nervous system and describe other studies in progress.
Eigenvalues of modulus 1

Proof. For w and z in C let w~z iff w and z are dependent. It is easy to verify that ~ is an equivalence relation. Let . Observe that each member of (P is denumerably infinite. Thus an uncountable set V must intersect uncountably many members of (P. We may take for U any set obtained by selecting exactly one member from each of the nonvoid members of {Pr\V:PE
Stability of oxygen point defects in UO 2 by first-principles DFT + U calculations: Occupation matrix control and Jahn-Teller distortion

Point-defect formation energies in uranium dioxide ${\text{UO}}_{2}$ are still a matter of debate due to the significant discrepancies between the various studies published in the literature. These discrepancies stem from the density functional theory $(\text{DFT})+U$ approximation that creates multiple energy minima and complexifies the search for the ground state. We report here $\text{DFT}+U$ values of the formation energies for the single oxygen interstitial and vacancy in ${\text{UO}}_{2}$, both in the fluorite and the Jahn-Teller distorted structures, using a scheme developed on bulk ${\text{UO}}_{2}$ [B. Dorado, B. Amadon, M. Freyss, and M. Bertolus, Phys. Rev. B 79, 235125 (2009)] and based on occupation matrix control. We first investigate the Jahn-Teller distortion in ${\text{UO}}_{2}$ in the noncollinear antiferromagnetic order and we show that the distortion stabilizes the system by $50\text{ }\text{meV}/{\text{UO}}_{2}$ compared to the fluorite structure. Moreover, it is found that the oxygen atoms are displaced in the $⟨111⟩$ directions, in agreement with experiments. For the bulk fluorite structure, we show that the use of the Dudarev approach of the $\text{DFT}+U$ without occupation matrix control systematically yields the first metastable state, located $45\text{ }\text{meV}/{\text{UO}}_{2}$ above the ground state. As a result, all previously published point-defect formation energies are largely underestimated. We then use the occupation matrix control scheme to calculate the formation energies of the single oxygen interstitial and vacancy in ${\text{UO}}_{2}$. We confirm that this scheme always allows one to reach the lowest energy states and therefore yields reliable formation energies. Finally, we compare our values with those obtained in previous studies and show that the discrepancies observed stem from the calculations of defective supercells which have reached different metastable states.
Distribution and flight heights of Sandwich Terns Thalasseus sandvicensis during different behaviours near wind farms in the Netherlands

ABSTRACT Flight heights and behaviour of 1460 Sandwich Terns Thalasseus sandvicensis in the Dutch North Sea were recorded with a laser range finder during ship-based surveys in 2020 and 2021. Over 87% of all Sandwich Terns were flying below 20 m, and fewer than 1.5% were recorded above 40 m, leading to a two-fold increase in the collision risk model estimates for the Borssele offshore wind farm in the Netherlands compared to the current standard flight height distributions.
Two Results on Union-Closed Families

We show that there is some absolute constant $c>0$, such that for any union-closed family $\mathcal{F} \subseteq 2^{[n]}$, if \mbox{$|\mathcal{F}| \geq (\frac{1}{2}-c)2^n$}, then there is some element $i \in [n]$ that appears in at least half of the sets of $\mathcal{F}$. We also show that for any union-closed family $\mathcal{F} \subseteq 2^{[n]}$, the number of sets which are not in $\mathcal{F}$ that cover a set in $\mathcal{F}$ is at most $2^{n-1}$, and provide examples where the inequality is tight.
On the Surjectivity of Certain Maps

We prove in this article the surjectivity of three maps. We prove in Theorem $1.6$ the surjectivity of the Chinese remainder reduction map associated to the projective space of an ideal with a given factorization into ideals whose radicals are pairwise distinct maximal ideals. In Theorem $1.7$ we prove the surjectivity of the reduction map of the strong approximation type for a ring quotiented by an ideal which satisfies unital set condition. In Theorem $1.8$ we prove for Dedekind type domains which include Dedekind domains, for $k\geq 2$, the map from $k$-dimensional special linear group to the product of projective spaces of $k$ mutually co-maximal ideals associating the $k$-rows or $k$-columns is surjective. Finally this article leads to three interesting questions $[1.9, 1.10, 1.11]$ mentioned in the introduction section.
Is the Zero-P Spacer Suitable for 3-Level Anterior Cervical Discectomy and Fusion Surgery in Terms of Sagittal Alignment Reconstruction: A Comparison Study with Traditional Plate and Cage System

The Zero-P spacer was primarily developed aiming to reduce the morbidity associated with the traditional anterior cervical plate. During the past decade, many authors have reported the use of Zero-P spacers for anterior cervical discectomy and fusion (ACDF) of one or two segments. Nevertheless, there is still a paucity of knowledge on the safety and feasibility of using Zero-P spacers for 3-level fixation. The objective of this study was to investigate the clinical and radiological outcomes, with a focus on the sagittal alignment reconstruction of 3-level ACDF surgery using Zero-P spacers versus those using a traditional plate and cage system. From Sep 2013 to Aug 2016, a total of 44 patients who received 3-level ACDF surgery due to cervical spondylotic myelopathy were recruited. The Zero-P spacer was used in 23 patients (group ZP) and the traditional plate and cage system in 21 (group PC). Clinical outcomes were analyzed by Neck Disability Index (NDI) and Japanese Orthopedic Association (JOA) scores, and dysphagia was evaluated using the Bazaz score. Radiological outcomes, including fusion rate, adjacent segment degeneration (ASD), and especially changes in cervical sagittal alignment, were analyzed. The NDI and JOA scores did not differ significantly between the two groups postoperatively (p > 0.05); however, there was significantly less dysphagia in patients using Zero-P spacers at the 3- and 6-month follow-up (p < 0.05). At the 24-month follow-up, the fusion rate and ASD were similar between the two groups (p > 0.05). Interestingly, patients using Zero-P spacers had a significantly lower postoperative C2-7 Cobb angle and fused segment Cobb angle, compared to those using a traditional plate and cage system (p < 0.05); meanwhile, the fused segment disc wedge was also found to be significantly smaller in patients using Zero-P spacers after surgery (p < 0.05). Moreover, we further divided patients into subgroups according to their cervical lordosis. In patients with a preoperative C2-7 Cobb angle ≤ 10°, significantly less cervical and local lordosis, as well as disc wedge, were seen in group ZP after surgery (p < 0.05), while in others with a preoperative C2-7 Cobb angle > 10°, no significant difference in postoperative changes of the cervical sagittal alignment was seen between group ZP and group PC (p > 0.05). Zero-P spacers used in 3-level ACDF surgery could provide equivalent clinical outcomes and a lower rate of postoperative dysphagia, compared to the traditional plate and cage system. However, our results showed that it was inferior to the cervical plate in terms of sagittal alignment reconstruction for 3-level fixation. We recommend applying Zero-P spacers for 3-level ACDF in patients with good preoperative cervical lordosis (C2-7 Cobb angle > 10°), in order to restore and maintain physiological curvature of the cervical spine postoperatively.
n-DIMENSIONAL PROJECTIVE VARIETIES WITH THE ACTION OF AN ABELIAN GROUP OF RANK n − 1

Let X be a normal projective variety of dimension n ≥ 3 admitting the action of the group G := Zn 1 such that every non-trivial element of G is of positive entropy. We show: 'X is not rationally connected' ⇒ 'X is G-equivariant birational to the quotient of a complex torus' ⇐⇒ 'KX + D is pseudo-effective for some G-periodic effective fractional divisor D. ' See Main Theorem 2.5. To apply, one uses the above and fact: 'the Kodaira dimension �(X) ≥ 0' ⇒ 'X is not uniruled' ⇒ 'X is not rationally connected. ' We may generalize the result to the case of solvable G as in Remark 2.7.
Surface roughness effects on turbulent boundary layer structures

A turbulent boundary layer structure which develop over a κ-type rough wall displays several differences with those found on a smooth surface. The magnitude of the wake strength depends on the wall roughness. In the near-wall region, the contribution to the Reynolds shear stress fraction, corresponding to each event, strongly depends on the wall roughness. In the wall region, the diffusion factors are influenced by the wall roughness where the sweep events largely dominate the ejection events. This trend is reversed for the smooth-wall. Particle Image Velocimetry technique (PIV) is used to obtain the fluctuating flow field in the turbulent boundary layer in order to confirm this behavior. The energy budget analysis shows that the main difference between rough- and smooth-walls appears near the wall where the transport terms are larger for smooth-wall. Vertical and longitudinal turbulent flux of the shear stress on both smooth and rough surfaces is compared to those predicted by a turbulence model. The present results confirm that any turbulence model must take into account the effects of the surface roughness
Well-posedness and numerical treatment of the Blackstock equation in nonlinear acoustics

We study the Blackstock equation which models the propagation of nonlinear sound waves through dissipative fluids. Global well-posedness of the model with homogeneous Dirichlet boundary conditions is shown for small initial data. To this end, we employ a fixed-point technique coupled with well-posedness results for a linearized model and appropriate energy estimates. Furthermore, we obtain exponential decay for the energy of the solution. We present additionally a finite element-based method for solving the Blackstock equation and illustrate the behavior of solutions through several numerical experiments.
K-theory of Rotation Algebra Crossed Products by Amalgamated Products of Finite Cyclic Groups.

The $K$-groups of the crossed product of the rotation C*-algebra $A_\theta$ by free and amalgamated products of the cyclic groups $\mathbb Z_n$, for $n=2,3,4,6$, are calculated. The actions here arise from the canonical actions of these groups on the rotation algebra under the flip, cubic, Fourier, and hexic automorphisms, respectively. An interesting feature in this study is that although the inclusion $A_\theta \to A_\theta \rtimes \mathbb Z_n$ induces injective maps on their $K_0$-groups, the same is not the case for the inclusions $A_\theta \rtimes \mathbb Z_d \to A_\theta \rtimes \mathbb Z_n$ for $2\le d < n \le 6$ and $d|n$, which we endeavor to calculate. Further, while for free products $K_1(A_\theta \rtimes [\mathbb Z_{m} \ast \mathbb Z_{n}]) = 0$, for amalgamated products $K_1(A_\theta \rtimes [\mathbb Z_{m} \ast_{\mathbb Z_{d}} \mathbb Z_{n}]) = \mathbb Z^k$ is non-vanishing ($k=1,2$).
On Rham cohomology of locally trivial Lie groupoids over triangulated manifolds

Based on the isomorphism between Lie algebroid cohomology and piecewise smooth cohomology of a transitive Lie algebroid, it is proved that the Rham cohomology of a locally trivial Lie groupoid G on a smooth manifold M is isomorphic to the piecewise Rham cohomology of G, in which G and M are manifolds without boundary and M is smoothly triangulated by a finite simplicial complex K such that, for each simplex ∆ of K, the inverse images of ∆ by the source and target mappings of G are transverses submanifolds in the ambient space G. As a consequence, it is shown that the piecewise de Rham cohomology of G does not depend on the triangulation of the base.
Dimension theory for linear solenoids

We develop the dimension theory for a class of linear solenoids, which have a ”fractal” attractor. We will find the dimension of the attractor, proof formulas for the dimension of ergodic measures on this attractor and discuss the question whether there exists a measure of full dimension. MSC 2000: 37C45, 28D20, 28A80
Scattering Study of Fermions Due to Double Dirac Delta Potential in Quaternionic Relativistic Quantum Mechanics

Scattering discussion due to Double Dirac Equation in Quaternionic version of relativistic quantum mechanics has been studied in this paper in details. In such a quantum mechanics Dirac equation in presence vector and scalar potential has been considered. Then a Quaternionic double Dirac delta potential comes to our considered system which causes to scatter the particles. Scattering states of the particles have been derived as well as reflected and transmission coefficients are calculated.
E-portfolio as an academic writing assessment tool in higher education: Strengths and challenges

This study investigated the use of an e-Portfolio for assessment at a Malaysian public university. Prior to the advent of the Internet, paper portfolios are ubiquitous forms of projects and assessments. However, they have limitations in terms of portability, shareability, and delayed two-way communication between instructors and students about progress. In lieu of paper portfolio, the e-Portfolio was introduced in an advanced English language course at a public university in Malaysia. The novelty of the e-Portfolio’s implementation renders it necessary to seek the insights of those who are directly involved in its use. Therefore, this study aims to explore the perceptions of the instructors and students regarding their use of the e-Portfolio throughout the course. This is a qualitative study whereby the main data collection method involved interviews. The data were imported to NVivo 12, and thematic analysis was used as the primary method of data analysis. A total of three instructors and 18 students participated in this study. The findings reveal that the instructors and students perceived the contribution of the e-Portfolio in the aspects of writing stages, digital artefacts, accessibility, personalised writing experience, feedback and communication, and motivation. The results demonstrate that mutually perceived challenges by the instructors and students were poor Internet connectivity and difficulty adapting to the e-Portfolio. The study highlights the benefits and shortcomings of using the e-Portfolio as an assessment tool for academic writing. This will guide practitioners and researchers to better implement the e-Portfolio in higher education institutions.
Strategies for the next cycles of intrapopulation improvement of sour passion fruit

ABSTRACT In breeding programs, the identification of genetic variability and knowledge of genetic constitutions existing within segregating populations are of fundamental importance for the success and continuation of the program. The present study aimed to quantify the genetic diversity among progenies of a sour passion fruit population based on morphoagronomic variables of flowers and fruits using the Ward-MLM (modified location model) procedure, which was efficient in quantifying genetic diversity and allowed the identification and consistent formation of three groups within the population. Among the groups formed, group I presented the highest means for the variables related to flowers, group II presented the highest values for the variables related to yield, and group III presented the highest means for the variables related to fruit quality. The androgynous length, nectariferous chamber length, anther surface, nectareous chamber length, and stigma surface were the variables that most contributed to the divergence between the evaluated genotypes. Crosses between groups II and III genotypes are promising for the next cycle, contributing to increased production and improvement of the physical and chemical quality of fruits.
Mixed-Order Relation-Aware Recurrent Neural Networks for Spatio-Temporal Forecasting

Spatio-temporal forecasting has a wide range of applications in smart city efforts, such as traffic forecasting and air quality prediction. Graph Convolutional Recurrent Neural Networks (GCRNN) are the state-of-the-art methods for this problem, which learn temporal dependencies by RNNs and exploit pairwise node proximity to model spatial dependencies. However, the spatial relations in real data are not simply pairwise but sometimes in a higher order among multiple nodes. Moreover, spatio-temporal sequences deriving from nature are often regulated by known or unknown physical laws. GCRNNs rarely take into account the underlying physics in real-world systems, which may result in degenerated performance. To address these issues, we devise a general model called Mixed-Order Relation-Aware RNN (MixRNN+) for spatio-temporal forecasting. Specifically, our MixRNN+ captures the complex mixed-order spatial relations of nodes through a newly proposed building block called Mixer, and simultaneously addressing the underlying physics by the integration of a new residual update strategy. Experimental results on three forecasting tasks in smart city applications (including traffic speed, taxi flow, and air quality prediction) demonstrate the superiority of our model against the state-of-the-art methods. We have also deployed a cloud-based system using our method as the bedrock model to show its practicality.
Habitual night waking associates with dynamics of waking cortical theta power in infancy

Abstract The implications of the substantial individual differences in infant sleep for early brain development remain unclear. Here, we examined whether night sleep quality relates to daytime brain activity, operationalized through measures of EEG theta power and its dynamic modulation, which have been previously linked to later cognitive development. For this longitudinal study, 76 typically developing infants were studied (age: 4–14 months, 166 individual study visits) over the course of 6 months with one, two, three, or four lab visits. Habitual sleep was measured with a 7‐day sleep diary and actigraphy, and the Brief Infant Sleep Questionnaire. Twenty‐channel EEG was recorded while infants watched multiple rounds of videos of women singing nursery rhymes; oscillatory power in the theta band was extracted. Key metrics were average theta across stimuli and the slope of change in theta within the first novel movie. Both objective and subjective sleep assessment methods showed a relationship between more night waking and higher overall theta power and reduced dynamic modulation of theta over the course of the novel video stimuli. These results may indicate altered learning and consolidation in infants with more disrupted night sleep, which may have implications for cognitive development.