Miracle-dz/UniFAR-FTUs huggingface dataset:
Convective precipitation over a Mediterranean area: From identification to trend analysis starting from high‐resolution rain gauges data

Heavy rainfall events are likely to become more frequent and severe in the next future, under the effects of a changing climate. In this context, the scientific literature is characterized by a relevant number of studies trying to identify the convective component of precipitation, since this kind of phenomena, due to their short duration and high intensity, may lead to an increased risk of flash floods or debris flows and, consequently, human life losses and economic damages. In this study, a separation between the convective and stratiform precipitation, starting from the subhourly precipitation time series recorded over Sicily (Italy), is provided on a monthly scale. Results show that the percentage of convective precipitation increases as the associated intensity increases, following what is generally known about convective events. Moreover, during the summer months, higher percentages of convective rainfall are generally reached for lower values of intensity, since this season favours the occurrence of these phenomena due to high temperature and relative humidity. In addition to the regional analysis, even an at‐site analysis has been carried out, through the definition of a critical intensity threshold to identify the predominant convective component for each rain gauge. This analysis has pointed out that such convective events have occurred mainly in the east part of the island mainly due to the complex orography of this area, which favours the occurrence not only of such phenomena but of flash floods and debris flows as well.
Effect of Testosterone on the Extinction Period of Morphine-induced CPP in Male Rats

Background: Sex-related differences in the incidence, prevalence, symptoms, and side effects of drug use, especially narcotics, have been previously shown in animal models and human studies. Objectives: In the presents study, the effects of different doses of testosterone on morphine extinction period were investigated in a rat model. Methods: Forty mature male Wistar rats were randomly allocated to four categories (10 in each group), including control (received intramuscular injection of vehicle) and testosterone (received intramuscular injection of testosterone at 1, 2.5 and 5 mg/kg) during the extinction period. Conditioned place preference (CPP) test was done to assess the psychological phenomena of drug craving and relapse. The CPP score was calculated in five stages, including the baseline (preconditioning), acquisition (conditioning), expression (postconditioning), extinction, and reinstatement. Results: Our results demonstrated that testosterone (1, 2.5 and 5 mg/kg) significantly extended morphine extinction duration compared to the control group. It has been shown that dopamine neurotransmission in mesocorticolimbic system is affected by testosterone through androgen receptors in adolescence and alteration in testosterone level could affect drug use vulnerability. Conclutions: It seems that normalization of testosterone levels reduces the symptoms of opioid withdrawal syndrome and have important clinical implication for clinicians to understand the effects of testosterone dysregulation on the extinction and withdrawal periods.
Structure, Expression and Promoter Activity of Ubiquitin Genes From Rice (Oryza Sativa L.).

Successful transgenic plant production is largely dependent on the use o f suitable promoters. In this study, we describe isolation of rice ubiquitin genes, and demonstrate the potential utility o f the rice ubiquitin promoters in monocot transformation systems. Two polyubiquitin genes (RUBQI and RUBQ2) and two ubiquitin extension/fusion genes (RUBQ3 and RUBQ4) have been isolated from a rice genomic BAC library. DNA sequence data revealed that both RUBQI and RUBQ2 contained an open reading frame encoding a hexameric precursor ubiquitin and an intron immediate upstream o f the initiation codon. The two ubiquitin fusion/extension genes RUBQ3 and RUBQ4 contained one copy o f the ubiquitin coding region interrupted by an intron. Northern blot analyses using the 3’-untranslated region as gene specific probes showed that RUBQI and RUBQ2 were actively expressed in all rice plant tissues tested. Deletion analysis o f the 5'-upstream region o f RUBQ2 revealed a putative 70 bp enhancer region that produced a 2.5fold stimulatory effect on promoter activity. RUBQ2 promoter activity was dependent on the presence of its own intron since promoter activity was reduced to background levels when the intron was deleted. In transient assays, GUS activity from constructs containing RUBQ1 and RUBQ2 promoters in rice suspension cells was 10 to 15 fold greater than those using the 35S promoter, and 2 to 3 fold greater than constructs with the maize polyubiquitin Ubil promoter. In stable transformation experiments, GUS expression levels from constructs containing RUBQI or RUBQ2 promoters were 22 and 48-fold greater in stably transformed calli, and 8 to 35-fold greater in transgenic rice plants, respectively, compared to those from a construct containing the 35S promoter. A six fold increase in gene silencing events were observed
Personality and Age of Male National Team of Ukraine in Kyokushin Karate—Pilot Study

This article is a continuation of the research on personality in combat sports in karate. The authors’ goal was to verify the relationship between personality and age of kyokushin karate practitioners. The male national team of Ukraine in karate kyokushin (N = 7) participated in the personality study with the use of the Big Five model. The NEO-FFI (NEO Five-Factor Inventory) Personality Questionnaire was applied as a research tool and the package of statistical methods IBM SPSS Statistics 27.0 (IBM Polska, Warszawa, Poland) was used to compute the research results. The study showed that there were differences in the intensity of openness to experiences between individual samples only at the level of the statistical trend. Masters showed a higher level of openness to experiences in relation to juniors (p = 0.081) and seniors (p = 0.097). Also, a negative and strong correlation between the intensity of neuroticism and conscientiousness among the respondents was noted. A conclusion was drawn that, with age, karatekas probably manifest greater openness to experience, which is the result of their sports experience, high sports level and pro-health values of karate. On the other hand, good emotional adaptation of karatekas is strictly related to conscientiousness.
Design and Simulation of an Advanced Solid-state Photomultiplier for Fiber-Optic Communication Systems

Detection of weak infrared light is essential for high data rate fiber-optic communication systems since itsperformance depends heavily on the sensitivity and bandwidth of photodetectors. Semiconductor diodes are themost common types of photodetectors that are widely considered. Indium Arsenide (InAs), being an AvalanchePhotodiode (APD), has become a solid-state photodetector of choice owing to its ability to detect infrared light ofup to about 3.5 μm. In this work, the depletion width and electric field profile of p-i-n InAs were simulated andused to obtain the multiplication gain. The effect of combining a series of p-i-n InAs in order to obtain longerdepletion width for the purpose of achieving high multiplication gain was investigated. To achieve this main target,the work was designed in two stages. The first stage involved designing a simple p-n junction of InAs to test themodel. Further improvement of the design to increase the depletion region was carried out by sand-witching anintrinsic piece of semiconductor material between the p and n-regions to form p-i-n InAs. The results obtainedshowed that the modification led to an interesting increase in the depletion width, electric field and themultiplication gain. In the second stage, the series of p-i-n InAs were combined to form an “Advanced solid-statephotomultiplier”. For the first time, a larger depletion width was achieved and thus increased multiplication gain.The results presented deduced that this novel design is promising since an appreciable gain much greater than 1000was achieved at about 6 V. Therefore, this could be used as an alternative to photomultiplier tube as well as otherexpensive photodetectors available.
Aerodynamic study of a 3D backward facing double step applied to safer launch and recovery of helicopters on ships

This study is concerned about the safety of helicopter launch and recovery on frigates. Therefore, it consists in investigating the airwake of a simplified frigate, modeled by a 3D backward facing double step in order to have a better understanding of such 3D unsteady flows. The mean and fluctuating velocity fields have been analyzed mainly experimentally through PIV, hot-wire anemometry, oil-flow visualizations . This has enabled to observe 3D structures, confirmed by a numerical computation. In particular, the results show a mean flow asymmetry. A sensitivity study around the zero degree drift angle has shown that the flow is bi-stable for this geometry. This bi-stability has been observed in several wind-tunnels for a wide variety of upstream geometric conditions. The understanding of this phenomenon is required for future control of such complex flows.
An integrative redescription of Echiniscus quadrispinosus quadrispinosus Richters, 1902 (Heterotardigrada, Echiniscidae) from the terra typica in Taunus Mountain Range (Europe; Germany)

In the present study, we used an integrative taxonomy approach to redescribe a population of Echiniscus quadrispinosus quadrispinosus Richters, 1902 from the neotype locality in the Taunus Mountain Range (Germany). We found clear differences in the chaetotaxy formula between the life stages of E. q. quadrispinosus. The body appendages B are, in general, absent in juveniles. Moreover, in larvae all body lateral appendages, except for E, are absent. We also obtained DNA sequences of 18S rRNA, 28S rRNA, ITS-2, and COI of E. q. quadrispinosus from the neotype locality and three Norwegian populations. Comparison with the sequences available in GenBank showed low genetic differences between the neotypic population and specimens from other localities. Therefore, we decided to establish our specimens from Taunus Mountain Range as neotype and paraneotypes of E. q. quadrispinosus. We also discussed and amended the taxonomic status of three subspecies E. q. brachyspinosus Bartoš, 1934, E. q. cribrosus Murray, 1907 and E. q. fissispinosus Murray, 1907 and established them as junior synonyms of E. q. quadrispinosus. Finally, we also confirmed E. lichenorum Maucci, 1983 as a valid species, clearly different from E. q. quadrispinosus.
Electric Vehicle Charging Infrastructure in Croatia – First-Hand Experiences and Recommendations for Future Development

One of the most serious obstacles to massive deployment of electric vehicles is insufficient and cumbersome charging infrastructure. Both the number of charging points and their power capacity are often insufficient. On top of that, this new technology often suffers from many issues related to insufficient testing, immaturity and irregular handling. This paper summarizes the issues with the electric vehicle charging infrastructure and describes first-hand experiences with long-range electric vehicle trips originating from Zagreb, Croatia, during 2022. Issues with the charging points locations, power and availability are assessed. Based on these experiences, the paper provides some thoughts on the possible directions of the further development of the electric vehicle charging infrastructure in Croatia.
Thermoelectromechanical Response of a Piezoelectric Strip with Two Parallel Cracks of Different Lengths

This work is concerned with the thermoelectromechanical fracture behavior of two parallel cracks of different lengths in a piezoelectric material strip under thermal loading. The crack faces are assumed to be insulated thermally and electrically. Fourier transform techniques are used to reduce the mixed boundary value problems to two systems of singular integral equations. Numerical calculations are carried out, and detailed results are presented to illustrate the influence of the geometric parameters on the thermal stress and electric displacement intensity factors.
Multi‐step‐ahead flood forecasting using an improved BiLSTM‐S2S model

Rainfall–runoff modeling is a complex hydrological issue that still has room for improvement. This study developed a coupled bidirectional long short‐term memory (LSTM) with sequence‐to‐sequence (Seq2Seq) learning (BiLSTM‐Seq2seq) model to simulate multi‐step‐ahead runoff for flood events. The bidirectional LSTM with Seq2Seq learning (LSTM‐Seq2Seq) and multilayer perceptron (MLP) was set as benchmarks. The results show that: (1) root mean absolute error is reduced by approximately 19% up to 27%, and the Nash–Sutcliffe coefficient of efficiency is improved by 14% up to 34% for 6‐h‐ahead runoff prediction for BiLSTM‐Seq2Seq compared LSTM‐Seq2Seq and MLP; (2) The BiLSTM‐Seq2Seq model has good performance not only for one‐peak flood events but also for multi‐peak flood events; and (3) BiLSTM‐Seq2Seq can mitigate the time‐delay problem and time lag is shortened by 39% up to 69% in comparison to LSTM‐Seq2Seq and MLP. These results suggest that the time‐delay problem can be mitigated by BiLSTM‐Seq2Seq, which has excellent potential in time series predictions in the hydrological field.
Effect of Store Image, Social Media, and Perceived Risk on Purchase Intention of Specialty Stores

Fierce competition makes Specialty store entrepreneurs try to produce innovations to be able to create purchase intentions in their stores, several factors, such as store image, social media, perceived risk, are suspected to have an influence on purchase intentions towards Specialty Stores in Surabaya, therefore the authors conducted research on these factors on purchase intention. The research design used a causal research design, quantitative data. The sample population is 150 people who live in Surabaya. The sampling technique used in this study used non-probability sampling by purposive sampling. The data analysis technique used in this research is the Structural Equation Modeling (SEM) program LISREL 8.80. Based on the results of the analysis, it is confirmed that there is a positive influence between store image, Social Media, and perceived risk on purchase intention; and there is an indirect influence of store image and Social Media on purchase intention through perceived risk.
Familial Occurrence of KienbockÂ’s Disease

The human body has an elaborate system for managing and regulating the amount of key trace metals circulating in blood and stored in cells. Nutrient metals from our diet are incorporated into blood if blood levels are depleted, transported into cells if cellular levels are inadequate, or excreted if blood and cell levels are sufficient or overloaded. When this system fails to function properly, abnormal levels and ratios of trace metals can develop. One of the most common trace-metal imbalances is elevated copper and depressed zinc. The ratio of copper to zinc is clinically more important than the concentration of either of these trace metals [1]. There are 2-4 grams of Zn distributed throughout the human body [2]. Most zinc is in the brain, muscle, bones, kidney and liver, with the highest concentrations in the prostate and parts of the eye [3]. It is the second most abundant transition metal in organisms after iron and it is the only metal which appears in all enzyme classes [2,4]. Copper is also a vital dietary nutrient, although only small amounts of the metal are needed for well-being [5]. Although copper is the third most abundant trace metal in the body [behind iron and zinc], the total amount of copper in the body is only 75-100 milligrams [6]. Copper is present in every tissue of the body, but is stored primarily in the liver, with fewer amounts found in the brain, heart, kidney, and muscles.
Psychological impact of the covid-19 pandemic on healthcare workers in Kuwait

Objective: In this study, we aim to assess the prevalence of depression and anxiety among Health care workers during the COVID-19 outbreak in Kuwait. Methods: The study is a cross-sectional survey. An anonymous self-reported online questionnaire was administered. Patient Health Questionnaire-4 (PHQ-4) was used for assessment in addition to collecting demographic data and other data related to physical health and workplace characteristics. The fears of getting COVID-19 infection or transmitting the infection to their families was also assessed. Results: Altogether, 607 Health care workers completed the survey. The estimated prevalence of severe anxiety and depression was 26.9% (moderate to severe 54%). Younger (p<0.001), female (p< 0.001) Health care workers occupying junior grade jobs (p= 0.001) tended to show higher prevalence of anxiety and depression. Frontline Health care workers who did not receive personal protective equipment training (p< 0.001) or those who reported being forced to join frontlines (p= 0.002) had higher anxiety and depression scores. Risk factors for severe anxiety and depression included being physician (Odds ratio [OR] 2.55; p = 0.027) and younger age group (OR, 2.53; p<0.001). We found a significant correlation between PHQ-4score and the perceived fear of being infected (r = 0.53, p <0.001) or transmitting the infection to their families (r = 0.49, p <0.001). Conclusion: Our study showed a high prevalence of anxiety and depression among Health care workers in Kuwait. Young female Health care workers showed a higher prevalence of anxiety and depression during this pandemic.
Online Learning a Binary Labeling of a Graph

We investigate the problem of online learning a binary labeling of the vertices for a given graph. We design an algorithm, Majority, to solve the problem and show its optimality on clique graphs. For general graphs we derive a relevant mistake bound that relates the algorithm’s performance to the cut size (the number of edges between vertices with opposite labeling) and the maximum independent set in the graph. We next introduce a novel complexity measure of the true labeling the frontier and relate the number of mistakes incurred by Majority to this measure. This allows us to show, in contrast to previous known approaches, that our algorithm works well even when the cut size is bigger than the number of vertices. A detailed comparison with previous results is given.
BrainPhys Neuronal Media Support Physiological Function of Mitochondria in Mouse Primary Neuronal Cultures

In vitro neuronal cultures are extensively used in the field of neurosciences as they represent an accessible experimental tool for neuronal genetic manipulation, time-lapse imaging, and drug screening. Optimizing the cultivation of rodent primary neuronal cultures led to the development of defined media that support the growth and maintenance of different neuronal types. Recently, a new neuronal medium, BrainPhys (BP), was formulated envisioning the mimicry of brain physiological conditions and suitability for cultured human iPSC-derived neurons and rat primary neurons. However, its advantages in mouse primary neuronal cultures and its effects in neuronal bioenergetics are yet to be demonstrated. In this study, we validated the beneficial use of BP in mouse primary neuronal cultures based on the observation that neuronal cultures in BP media showed enhanced ATP levels, which increased throughout neuronal maturation, a finding that correlates with higher mitochondrial activity and ATP production at later maturation stages, as well as an increased glycolysis response on mitochondrial inhibition and increased mitochondrial fuel flexibility. Taken together, our data demonstrate that BP medium promotes mitochondrial activity along with neuronal maturation of in vitro cultures.
Is Human Vomeronasal Organ A Myth or A Neglected Structure?

The human vomeronasal organ (VNO) is a structure situated under the anteroinferior side of the nasal septum. It is mainly described in the rodents and found as a part of the accessory olfactory system. It has been shown to consist of specialized olfactory sensory cells, which function in perception of pheromones. With a large number of literature on the human VNO, there is little concensus of its persistence and functionality in human. During a routine dissection of nasal cavity, we recognized a one-sided vomeronasal pit in one of the six fresh-frozen cadavers (17 %) and described the position and structure of this rare structure morphologically. The present study summarizes the literature about the VNO and describes its structural and functional findings.
The Effect of Training and Development on Employee Performance Against Innovative Work Behavior as a Mediation Variable at PT. Telkom Banda Aceh

This study was to analyze the training and development effect on employee innovative work behavior and employee performance in PT. Telkom Banda Aceh. The population was 202 people, they were the employees at PT. Telkom Banda Aceh. A sampling of each unit was done at simple random by lottery. Determination of the sample used the Stratified Random Sampling technique based on the grid. The number of samples was determined by the Slovin formula so that 134 people were obtained. Data were analyzed through structural equation modeling (SEM). Result reveals that in the PT. Telkom Banda Aceh, training, development, innovative work behavior, and employee performance of PT. Telkom Banda Aceh has been going well, training affects the performance of employees, development affects the performance of employees, training affects the innovative work behavior of employees, development affects the innovative work behavior of employees, innovative work behavior affects the performance of employees, training affects employee performance through innovative work behavior of employees, Development affects employee performance through innovation in employee work behavior. In the model, we can see that the innovative work behavior acts as a partial mediator. So the function of improving employee performance at PT. Telkom Banda Aceh is a function of increasing the frequency and quality of training and development, as well as increasing the innovative work behavior of its employees. These findings can be the basis of academic theory and can be developed for further research by adding other variables to the model.
Application and Design of Switches Used in CAR

Among the many oncology therapies, few have generated as much excitement as CAR-T. The success of CAR therapy would not have been possible without the many discoveries that preceded it, most notably, the Nobel Prize-winning breakthroughs in cellular immunity. However, despite the fact that CAR-T already offers not only hope for development, but measurable results in the treatment of hematological malignancies, CAR-T still cannot be safely applied to solid tumors. The reason for this is, among other things, the lack of tumor-specific antigens which, in therapy, threatens to cause a lethal attack of lymphocytes on healthy cells. In the case of hematological malignancies, dangerous complications such as cytokine release syndrome may occur. Scientists have responded to these clinical challenges with molecular switches. They make it possible to remotely control CAR lymphocytes after they have already been administered to the patient. Moreover, they offer many additional capabilities. For example, they can be used to switch CAR antigenic specificity, create logic gates, or produce local activation under heat or light. They can also be coupled with costimulatory domains, used for the regulation of interleukin secretion, or to prevent CAR exhaustion. More complex modifications will probably require a combination of reprogramming (iPSc) technology with genome editing (CRISPR) and allogenic (off the shelf) CAR-T production.