Miracle-dz/UniFAR-FTUs huggingface dataset:
Promising methods, questionable results: Developing an inverse model of the fossil ridge-transform intersection in the Troodos ophiolite in Cyprus

Introduction . 1 Geologic Background . 2 Cyprus . 2 Mathematic Background . 4 Modeling. 4 Continuum Mechanics. 6 Temperature Relationship to Young’s Modulus . 8 Prediction of Data . 10 Statistics. 10 Implementation . 13 Finite Element Analysis . 13 Optimization Implementation . 18 Results . 21 Small Dataset . 21 Full Dataset . 22 Discussion . 24 Results . 24 Shortcomings of the Model . 26 Problems With Implementation and Assumptions . 26 Did Past Studies Test for High Coupling Rates? 28 Problems Related to PyLith . 29 Conclusion . 30 Acknowledgements . 31 References . 32 Promising methods, questionable results: developing an inverse model of the fossil ridge-transform intersection in the Troodos ophiolite in Cyprus Matt Carter Senior Integrative Exercise March 13, 2019 Advisors: Dr. Sarah Titus, Carleton College Dr. Joshua Davis, Carleton College ABSTRACT Forward models are commonly used to investigate the stress regime of ridgetransform intersections. However, none of these previous studies have used real data to create an inverse model. I used forward modeling and a maximum likelihood estimate to create an inverse model of the fossil ridge-transform intersection in the Troodos ophiolite in Cyprus. I use the forward model to predict the spreading rate, rate of left lateral slip, and thermal properties based on observed dike pole directions. With this analysis, I find a half-spreading rate of 101.2 mm/yr and a slip rate 10.3 mm/yr best fit the observed dike pole orientations. The ratio of slip to spreading rate is much lower than predicted by previous forward models of ridge-transform intersections. However, the predicted orientations in the best case are still significantly different from the observed orientations, which indicates that there are likely problems with the model, its implementation, and perhaps with its assumptions about the behavior of dikes themselves.
Shipping noise predictions from AIS in the Faial-Pico area, Azores archipelago

The Azores archipelago, lying on the North Atlantic (NA) ocean, hosts one of the greatest diversities of cetaceans, and is an important habitat for several resident and migratory species. However, this unique diversity may be at risk due to the ocean noise generated by increasing commercial and recreational vessel traffic in the area. AIS shipping distribution and water column variability, together with suitable numerical propagation models were used to generate noise level maps for the area around Faial-Pico-São Jorge Islands, during June 2018. The generated noise level time-space distribution generally agrees with detected environmental variability and known navigation in the area, namely ferries between islands and fishing patterns.
Optimization of long-term Breast Cancer Cell Culture using live Imaging in an automated Perfusion System

I A significant quantity of questions remains in cellular biology. Some of them cannot be answered by applying traditional analytical techniques and request the development of new tools for research. Nowadays, the integration of microdevices and analytical platforms enables the acquisition of biological data in an agile and low-cost manner. Additionally, perfusion technologies allow us to recreate physiological microenvironments. For this reason, the integration of live-cell microscopy, perfusion, and microsystems, will enable control of the delivery of soluble factors and the tracking of single cells. These platforms have a vast potential to result in a better understanding of cell behavior, generating evidence for potential predictive models for disease treatment. We have developed a robust live-imaging fluidic system for studying breast cancer cells. Our data suggest fast and short pulses as the preferred strategy for perfused assays. This system will be the basis for further analysis of the effect of stimulatory growth factors and cytotoxic or cytostatic agents with therapeutic potential. Furthermore, we offer an overview of the challenges and considerations in the development of automated microsystems.
PII: S0022-247X(02)00419-5

We study the singular integral operator fx,t (y ′) = f (x − ty′), defined on all test functions f , whereb is a bounded function, α 0, Ω is suitable distribution on the unit sphere Sn−1 satisfying some cancellation conditions. We prove certain boundedness properties of TΩ,α on the Triebel–Lizorkin spaces and on the Besov spaces. We also use our results to study the Littlewood–Paley functions. These results improve and extend some well-known results.  2002 Elsevier Science (USA). All rights reserved.
ANALYSIS OF FACTOR AFFECTING INFANT MORTALITY RATE (IMR) IN EAST JAVA USING MULTIPLE LINEAR REGRESSION

Infant Mortality Rate (IMR) is one of the important indicators in public health. Indonesia still has a relatively high IMR compared to the neighboring countries. Based on the Indonesian Demographic Health Survey (IDHS) in 2012, IMR in East Java reached 25.50 deaths per 1000 births. IMR decline occurred during 2012 to 2015. Achievement depends on the factors that influence it. This study aims to create a model of IMR based on maternal and external factors in East Java. The method used was a non-reactive study using 38 districts/cities as sample units in East Java, which came from Central Bureau of Statistics secondary data in 2015. Statistical analysis used multiple linear regression. The results showed the independent variables together affected the IMR (p-value = 0,000 <0.05), but partially influenced by the age of the first married mother (p-value = 0,000 <0.05) and the helper delivery of non-medical personnel (p-value = 0.014 <0.05). The conclusion of this study is the regression equation model for IMR in East Java in 2015, which is IMR = 1,064 + 1,319 * (age of first marriage) + 0.439 * (helper of non-medical births). Suggestions for the Government of East Java Province to implement strategies so that infant mortality cases can be reduced.
Morphology of preimaginal stages of Minettia longipennis Fabricius (Diptera: Lauxaniidae) MAREK SEMELBAUER & MILAN KOZÁNEK (Slovakia)

Scanning electron microscopy documentation of all preimaginal stages of the lauxaniid species Minettia longipennis (Fabricius) is presented for the first time. Images of the following morphological structures of all larval instars are provided: pseudocephalon, antenna, maxillary palpus, facial mask, cirri, mouth hooks, ambulatory lobes, anterior and posterior spiracles. Illustrations of the cephalopharyngeal skeleton for all three instars in lateral, ventral and dorsal views are provided. All instars are clearly separable by morphological features. The first instar has unique modification of the facial mask and structure of the cephalopharyngeal skeleton. Second and third instars are similar in overall form and differ in details in structure of the mouthooks and anterior spiracles, and by the number of pharyngeal ridges.
CONCEPT ON LANDMARK DETECTION IN ROAD SCENE IMAGES TAKEN FROM A TOP-VIEW CAMERA SYSTEM

Abstract. In this paper, we demonstrate the inclusion of a top-view camera system mounted on a city bus in an existing sensor setup. A novel sensor setup with five down-facing cameras is mounted on the roof of a MAN Lion’s City 12 city bus to extract landmarks in road scene images. Its positioning is validated by an exemplary detection of lane markings. The concept for further landmark detection with the help of the presented camera system is explained in this paper and sensor data fusion methods are proposed. Based on our previous findings (Albrecht et al., 2019), strengths of the novel sensor system are introduced to improve the current environment perception system. For now, only a qualitative observation of the capability to detect lane markings and other landmarks can be presented. Future work will use the current findings for landmark detection for a vehicle self-localization system.
Confirmatory and supportive laboratory investigations in SARS-CoV-2 infection; a systematic review

The pandemic of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread over 210 countries. In order to mitigate the epidemic and to flatten the curve, apart from multiple containment measures, an accurate identification of those infected is imperative. The objective of this review was to review, systematically, the performance of diagnostic and screening technologies and the yield of different clinical samples for the detection of SARS-CoV-2. Here we have critically evaluated the results obtained from different clinical samples and laboratory investigations and the performance of rRT-PCR (real-time reverse transcriptase polymerase chain reaction) technique in the diagnosis of SARS-CoV-2.
Price Discrimination along Multiple Dimensions: New Evidence from a Regional Airline

I examine the case of a firm that practices both second-degree and third-degree price discrimination. I present a model showing conditions under which the premium for higher quality can either rise or fall as the firm implements group pricing. I then use new data from a regional airline to estimate how the two kinds of price discrimination interact, and how each is affected by changes in competition. I establish three key results, all new to the literature. First, in different markets, the two kinds of price discrimination can either offset or reinforce each other, in a manner that fits the model's predictions. Second, inter-temporal differences in prices are purely driven by price discrimination, rather than by scarcity pricing. Third, competition increases the extent of both kinds of price discrimination.
Helicobacter pylori Infections andAssociated Risk Factors among Women of Child Bearing Age due to infections by Helicobacter pylori in rural areas of Larkana, Sindh

Background. Early detection and treatment of Helicobacter pylori (H. pylori) infection in women of child bearing ages may reduce the risk of maternal health disorder. This study was conducted to determine the burden of H. pylori infections and associated risk factors among women of child bearing ages in rural areas of Larkana, Sindh. Methods. Facility based cross sectional study design was conducted from April to October 2019. The study recruited 195 pregnant and 137 non-pregnant women with age range of 16-40 years. Sociodemographic data of study participants were collected by structured questionnaire. Venous blood was analyzed to determine hemoglobin, H. pylori stool antigen test kit was used to assess H. pylori infection, and fresh fecal (stool) was used to examine intestinal parasites among study subjects. Data was entered and analyzed using SPSS version 21.0. Bivariate and multivariate logistic regression model using odds ratio (OR) at 95% confidence interval (CI) were calculated. P-value less than 0.05 was taken as statistically significant. Results. The overall burden of H. pylori infection among study participants was 29% (96/332). H. pylori infection was statistically significantly associated with pregnancy status (AOR: 1.825, CI (1.42-2.15), P=0.020), history of hyperemesis gravidarum (AOR=7.028, C.I (2.47-19.99), P=0.018), and low hemoglobin value (AOR=0.177, CI (0.083–0.379), p=0.003). There was no statistically significant association between H. pylori infection and sociodemographic characteristics and some expected risk factors like smoking, Khat chewing, alcohol drinking habit, and presence of intestinal parasites. Conclusion. In this study, H. pylori infection was still a public health problem in the study area. H. pylori infected women also had high rate of anemia compared to women who had not H. pylori infected. Hence clinician and other responsible bodies should give a special attention for women who had been infected with H. pylori. Further large case control studies are warranted to understand more the role of H. pylori, HG, and other associated risk factors. ----------------------------------------------------------------------------------------------------------------------------------Date of Submission: 07-05-2020 Date of Acceptance: 21-05-2020 ----------------------------------------------------------------------------------------------------------------------------------
Exogenous EBR mediated the plant growth and absorption and accumulation of Cu, Fe and Zn in tomato seedlings under Cu stress

As an essential element and a heavy metal, copper(Cu) occurs in various vital movements and metabolic processes of plant. In previous industrial and agricultural production, excess Cu2+ or Cu compounds were frequently intentionally or unintentionally discharged into the environment. In some polluted soils, Cu content exceeded ten times the original content of the soil. This led to fatal damages to plant growth and food security, and thus developing new phytoremediation pathways were imperative. Our early studies showed that exogenous 2,4-epibrassinolide(EBR) alleviated Cu stress and increased Cu accumulation in tomato seedlings. ‘Gailiang Maofen 802F1' was used as the plant material to explore the alleviation mechanism of EBR on tomato seedlings under Cu stress. Through nutrient solution cultivation in greenhouse conditions, we investigated the effects of EBR on tomato growth and mineral elements contents under Cu stress. The results showed that exogenous EBR effectively alleviated growth strains induced by Cu stress. 50 μmol·L? 1 of CuCl2 obviously restrained tomato growth and increased Cu content in tomato seedlings. Compared with seedlings exposed to Cu stress, 0.1 mg·L? 1 of exogenous EBR effectively increased leaf chlorophyll content and plant biomass respectively by 39.6% and 20.0%. Under Cu stress, exogenous EBR observably reduced Cu absorption and transport, simultaneously increasing contents of iron(Fe) and zinc(Zn) in roots. EBR efficiently regulated different chemical forms and Cu, Fe, Zn distributions among subcellular organelles and reduced Cu biotoxicity in cells. This was helpful to the normal growth of tomato and ensured regular physiological and biochemical metabolism of roots and leaves. Cu stress increased contents of different chemical species of Cu in tomato leaves and root. Addition of EBR under Cu stress increased contents of all forms of Cu except NaCl extracted Cu in leaf, compared with Cu stress. Proportion of movable Cu increased in leaves, and decreased in roots under Cu stress. Under Cu stress, EBR application made the proportions of movable and un-moveable Cu similar to those of CK, which indicated exogenous EBR obviously regulated the Cu chemical form and subcellular distribution in plant.
Effects of the Supplementation of Euphorbia hirta L. in Feed on the In-Vitro Rumen Fermentation and Digestibility

DOI: 10.21276/sjavs.2018. 5.4. 9 Abstract: The purpose of this research was to analyze the effect of Patikan Kerbau (Euphorbia hirta L) flour on the in-vitro rumen fermentation and digestibility using goat rumen fluid. The materials of the research were rumen fluid of goats, forage, tofu waste and E. hirta flour. The research method was experimental using Randomized Block Design with 6 treatments and 4 groups of goat rumen fluid as replication. The treatments of this experiment were herbal supplements in feed with different formulations: P0= control feed (forage 60%: concentrate 40%); P1= P0 + 5% E. hirta (dry matter basis); P2= P0 + 10% E. hirta; P3= P0 + 15% E. hirta; P4= P0 + 20% E. hirta, and P5= P0 + 25% E. hirta. The measured variables were pH rumen fluid, concentration of N-NH3, concentration of total VFA, dry matter digestibility and organic matter digestibility in the rumen fluid incubation 48 hour. Data were analyzed using variance (ANOVA), if there any differences in treatment, then continued with Duncan Multiple Range Test (DMRT). The result of the research showed that supplementation of E. hirta in feed did not significantly (P>0.05) affect on rumen pH, but it highly significant affected (P<0.01) on the total VFA concentration, N-NH3 concentration, dry matter and organic matter digestibility of feed. Conclusion of the research was the supplementation of E. hirta can affect the in-vitro rumen fermentation and digestibility. The best treatment is the supplementation of E. hirta flour 15% (P3) in feed because it can increase the concentration of total VFA, concentration of N-NH3, dry matter in vitro digestibility and organic matter in vitro digestibility without changing the rumen fluid pH.
PROSOCIAL AND PROACTIVE SAFETY CITIZENSHIP BEHAVIOUR (SCB) Prosocial and proactive “safety citizenship behavio ur” (SCB): The mediation role of affective commitment and psyc hological ownership

Safety citizenship behaviour (SCB) is an important participation factor in work-groups. Our study aims to study the influence of some anteceden ts of this safety-specific dimension of organizational citizenship. In the light of the cur rent research stream that distinguishes between prosocial vs. proactive forms of organizati onal citizenship, we will investigate the effects of the following variables: organizational support for safety participation; team safety climate; psychological ownership toward the managem ent of safety; affective commitment toward the organization. The research was conducted in a multinational chemical industry (N = 314). Prosocial oriented forms of SCB (safety stewardship) were mainly related to the influence of affective dimensions of organizational belongingness (affective commitment) . On the other hand, proactive oriented forms of SCB (safety voice) showed higher linkages with the internalization of safety promotion instan ces (psychological ownership) . The conclusions of the article include conceptual impli cations for academic research and managerial practice. The aim of this is to support a broader safety citizenship orientation by the workforce in the management of safety related i nstances in the workplace.
Features of patients that died for COVID-19 in a hospital in the south of Mexico: A observational cohort study

Background: Due to the wide spread of SARS-CoV2 around the world, the risk of death in individuals with metabolic comorbidities has dangerously increased. Mexico has a high number of infected individuals and deaths by COVID-19, as well as an important burden of metabolic diseases. However, reports about features of Mexican individuals with COVID-19 are scarce. The aim of this study was to evaluate demographic features, clinical characteristics, and the pharmacological treatment of individuals who died by COVID-19 in the south of Mexico. Methods: We performed an observational study including 185 deceased individuals with confirmed diagnosis of COVID-19. Data were retrieved from medical records. Categorical data was expressed as proportions (%) and numerical data were expressed as mean, standard deviation. Comorbidities and overlapping symptoms where plotted as Venn diagrams. Drug clusters were plotted as dendrograms. Results: The mean age was 59.53 years. There was a male predominance (60.1%). The mean hospital stay was 4.75 days. The most frequent symptoms were dyspnea (88.77%), fever (71.42%) and dry cough (64.28%). Present comorbidities were diabetes (60.63%), hypertension (59.57%) and obesity (43.61%). The main drugs used were azithromycin (60.6%), hydroxychloroquine (53.0%) and oseltamivir (27.3%). Conclusions: Mexican individuals who died of COVID-19 had shorter hospital stays, higher frequency of shortness of breath, and higher prevalence of diabetes compared with individuals from other countries. Also, there was a high frequency of off-label use of drugs for their treatment.
Clinical Efficacy of Immune Checkpoint Inhibitors in Older Non-small-Cell Lung Cancer Patients: A Meta-Analysis

Background: Immune checkpoint inhibitors (ICIs) have transformed the treatment landscape among non-small-cell lung cancer (NSCLC) patients. The efficacy of ICI therapy in older patients (≥65 years) is controversial and not fully clarified. We performed a systematic review and meta-analysis to evaluate the efficacy of ICIs in patients with advanced or metastatic NSCLC based on age (<65 years vs. ≥65 years). Methods: A comprehensive literature search for eligible randomized control phase II/III trials that compared the efficacy of anti-PD-1/PD-L1 agents against chemotherapy in advanced or metastatic NSCLC patients. Pooled overall survival (OS) and progression-free survival (PFS) estimates were calculated based on random/fixed effects models according to the heterogeneity between the studies. Results: A total of 10 studies involving 8 randomized controlled trials (2 updates) were enrolled in this meta-analysis [2,662 young patients (<65 years) and 1,971 older patients (≥65 years)]. The efficacy of anti-PD-1/PD-L1 agents is comparable between young (<65 years) and older (≥65 years) patients for OS [HR 0.75 95% CI (0.64–0.88) vs. 0.76 95% CI (0.66–0.87)]. However, our pooled analysis was not sufficient to show a significant benefit in terms of PFS for anti-PD-1/PD-L1 agents [HR 0.87 95% CI (0.74–1.01), P = 0.06]. In addition, we failed to see a PFS superiority of anti-PD-1/PD-L1 agents against chemotherapy in two age subgroups [<65 years and ≥65 years, HR 0.85 95% CI (0.72–1.01), P = 0.07 and HR 0.87 95% CI (0.68–1.10), P = 0.25]. Conclusion: ICIs therapy presents comparable efficacy in older advanced or metastatic NSCLC patients with young patients.
Effect of Graded Levels of Nitrogen on Weeds in Winter Maize

Field experiment was conducted for two years (1994–95 and 1995–96) at Agricultural Research Station, Banswara to study the extent of weed problem at graded levels of nitrogen and to find out effective and economically viable system of controlling weeds in winter maize. Maximum weed control efficiency (69.5%) was achieved with post-emergence application (30–35 DAS) of atrazine at 1.0 kg/ha which was statistically on a par with its pre-enlergence application. Mechanically weeded (twice) treatment yielded 44.3% weed control efficiency. Application of atrazine 1.0 kg/ha as post-emergence had an edge in respect of grain yield of maizecompared to its pre-emergence application but both maintained their superiority over 2, 4-D application.