Miracle-dz/UniFAR-FTUs huggingface dataset:
Upper limit for tidal power with lateral bypass

We derive the upper limit for power extraction from an open-channel flow with lateral bypass representing tidal power or run-of-river plants for the complete range of blockage $\unicode[STIX]{x1D70E}$, Froude number $Fr_{2}$ and turbine head $H_{T}$. For this, a generic turbine model is used: a momentum and energy sink distributed over the geometric blocking $\unicode[STIX]{x1D70E}$ of the channel allowing lateral bypass. It is indicated that existing models neglect important aspects of the free-surface deformation due to the energy extraction, yielding unphysical behaviour at high blockage, high Froude number or high turbine head. The asymptotic validity of existing theories for $\unicode[STIX]{x1D70E}\rightarrow 0$, $Fr_{2}\rightarrow 0$, $H_{T}\rightarrow 0$ becomes evident: firstly, by comparing existing theories with the presented general theory; and secondly, by the experimental validation of the existing and presented theories. The accompanying systematic experimental study comprises a wide range of blockage ratios, $0.25\leqslant \unicode[STIX]{x1D70E}\leqslant 1.0$, of downstream Froude numbers, $0.2\leqslant Fr_{2}\leqslant 0.5$, and of different turbine heads, $H_{T}$, measured in multiples of the specific energy $E_{0}$ of the undisturbed flow. The subsequent model-based optimisation allows an indication of the optimal turbine head $H_{T,opt}/E_{0}$ as well as the maximal obtainable coefficient of performance $C_{P,opt}$ as a function of $\unicode[STIX]{x1D70E}$ and $Fr_{2}$ or downstream water depth $h_{2}/E_{0}$, respectively. The theory reveals points of operation in which there is a surge wave in the tailwater. The new physical insight and optimisation results may serve for plant design and operation, as well as for investment decisions.
The Determinants Influencing Managerial Accounting in Vietnamese Manufacturing and Trading Enterprises

Currently, there are few studies at the marco level to analyze the current development of managerial accounting in Vietnam. Based on literature review and multiple regression analysis, this study aims to examine the determinants influencing the development of managerial accounting in Vietnamese manufacturing and trading enterprises. The study collected primary data of 173 enterprises over 500 enterprises through a questionaire survey, representing the valid response rate of 34.6%. The research results show that age and size of enterprises, business environment, information needs of managers, product characteristics, and quality of accountants are the main determinants positively affecting the development of managerial accounting in the Vietnameses enterprises.
Who Pays for and Who Benefits from Minimum Wage Increases? Evidence from Israeli Tax Data on Business Owners and Workers

Abstract A key goal of a higher minimum wage is income redistribution towards low-income families. Existing research on the minimum wage focuses on the impact on affected workers, but is silent on the incomes of the owners of businesses who pay for a higher minimum wage. Higher minimum wages will do more to redistribute income if the owners of businesses who pay the minimum wage are nearer the top of the income distribution, and vice versa. We study evidence on the incidence of the minimum wage on the incomes of business owners using a unique administrative dataset on the universe of tax records for Israel, in the period surrounding a large minimum wage increase. We find that the minimum wage hike reduced profits of companies, with minimum-wage intensive companies bearing the bulk of the cost and adjusting their workforces more aggressively. Notably, profits declined more for lower-income business owners. Moreover, owners of businesses with higher shares of minimum-wage workers ranked at the bottom of the income distribution of business owners. In addition, spouses of business owners earn less than the owners while minimum wage workers have higher earning spouses, further reducing the redistributive effect of the minimum wage.
Are silver dressings effective antimicrobial therapies

Atlanta — In vitro assessment of the efficacy of silver dressings may not adequately reflect their performance in a clinical setting, according to Stephen C. Davis, research associate professor, department of dermatology and cutaneous surgery, University of Miami School of Medicine. Carlos Ricotti, M.D., a wound healing fellow with Prof. Davis, discussed their work on the antimicrobial efficacy of silver dressings at the 14th annual meeting of the Wound Healing Society.
Predicting Short-Term Traffic Speed Using a Deep Neural Network to Accommodate Citywide Spatio-Temporal Correlations

The traffic speed on a given road segment is affected by the current and past speeds on nearby segments, and the influence further cascades into the rest of a transport network. Thus, a successful forecasting model should consider not only the impact of neighboring road segments but also that of distant segments. Based on this principle, the approach proposed here projects the topology of a real traffic network into the structure of a deep neural network in order to accommodate citywide spatial correlations as well as temporal dependencies. This approach leads to interesting model interpretations in terms of traffic state transition and propagation, which form a basis for extending the proposed forecasting model. The present study was conducted with a large-scale data set collected over 10 months, and traffic speeds were successfully forecasted for 170 road segments in Gangnam, Seoul, Korea.
Postgraduate education among family and community physicians in Brazil: the Trajetorias MFC project

Neither primary health care or family and community medicine are recognized as knowledge areas in Brazil, for the purpose of postgraduate education (master's, Ph.D.) or research. Our objective was to describe the postgraduate education trajectories of family and community physicians in Brazil. In this observational, exploratory study, we used data from SBMFC and SisCNRM to compile the list of physicians and community physicians, and then downloaded their curricula vitae from the Lattes Platform, verifying all data for consistency. A master's degree was held by one in eight, and a Ph.D., by one in forty; most degrees were in collective health. Women (versus men) were less likely to hold master's degrees, and even less likely to hold Ph.D. degrees. Professional (versus academic) master's degrees and those in other areas (versus in medicine or collective health) were also associated with lower probability of obtaining a Ph.D. degree. Certified specialists (versus those with a medical residency) with a postgraduate degree were more likely to have earned it before becoming family and community physicians. We suggest that researchers in public health critically examine the relative benefits of different postgraduate trajectories for the professional performance of family and community physicians.
RBBP6 induces non-small cell lung cancer cell proliferation and high expression is associated with poor prognosis

Lung cancer is the most common cause of cancer-associated mortality in China with 85% of patients having non-small cell lung cancer (NSCLC). Identifying NSCLC driver genes and prognostic markers is critical to reducing these numbers. The studies of retinoblastoma binding protein 6 (RBBP6) performed on NSCLC is limited. The present study aimed to investigate the molecular function and the prognostic potential of RBBP6 in NSCLC using the A549 cell line and patient samples, respectively. The functional effect on cancer cell proliferation and prognostic value of RBBP6 were examined in vitro and in vivo using reverse transcription-quantitative PCR, immunofluorescence, immunohistochemistry (IHC) and xenograft implantation. The results demonstrated that RBBP6 mRNA expression was significantly higher in NSCLC tissues compared with in adjacent normal samples. When RBBP6 mRNA expression was interfered with using short hairpin RNA, A549 cell proliferation and xenograft tumor growth were reduced. Additionally, IHC and survival analysis demonstrated that patients with NSCLC with high expression levels of RBBP6 had a shorter median overall survival time compared with patients with low RBBP6 expression (31 vs. 51.5 months), and this was more prominent in stage I–II patients (43 vs. >67 months). High expression levels of RBBP6 indicated poor prognosis in patients with NSCLC. This may be due to the ability of RBBP6 to promote cancer cell proliferation. RBBP6 may be a potential prognostic biomarker and a therapeutic target for NSCLC.
Updated efficacy and tolerability of durvalumab in locally advanced or metastatic urothelial carcinoma.

286Background: Anti-PD-L1 immunotherapy has shown promising clinical activity in urothelial carcinoma (UC). We report on a planned update of efficacy and follow-up in patients (pts) receiving durvalumab for the treatment of locally advanced or metastatic UC. Methods: Pts received durvalumab 10 mg/kg Q2W up to 12 months (mo), unacceptable toxicity or confirmed progressive disease. Tumor PD-L1 expression was assessed using the validated Ventana SP263 assay (PD-L1 high = TC ≥ 25% or IC ≥ 25%). Primary endpoints were confirmed ORR by RECIST v1.1 with blinded independent central review (BICR) and safety. Duration of response (DoR) and overall survival (OS) were key secondary endpoints. Results: As of July 24, 2016 (data cutoff [DCO]), the primary efficacy population included 103 pts who were followed for at least 13 weeks (median duration of follow up 7.3 mo); 37% had ≥ 2 prior regimens; 97% had prior platinum treatment; 95% had visceral metastases; and 49% had liver metastases at baseline. As of the DCO, 21 p.
EBOLA VIRUS DISEASE (EVD) INFORMATION AWARENESS AMONG THE PEOPLE OF OGBOMOSO ENVIRONS

This study focused on Ebola Virus Disease (EVD) information awareness among the people of Ogbomoso environs. The study made use of cross sectional research design and data were collected with the aid of structured questionnaire from one hundred and fifty (150) respondents selected through a cluster sampling technique from three local government areas. Descriptive statistics was used for the study; this involved the use of percentage, frequency, cumulative and clustered bar charts to analyze variables. The data were analyzed using IBM Statistical Package for Social Science (SPSS). The findings showed that most of the respondents had high level of literacy. Majority of them were informed on Ebola virus disease (EVD) but were less informed regarding possibilities of transmission of the virus through partaking in funeral activities when compared with other means of transmission. Moreover a large percentage of 82 and 80 sourced their information from radio/ television and friends/colleaques respectively, among which radio and television was discorvered to be the most effective source. There is the need for government to establish EVD awareness and information sensitization centre where residents can have a quick access to EVD information, its mode of transmission and preventive measures in Ogbomoso town.
The Strategy of Bad Loans “Pang Pade Payu” in Village Credit Institution in Buleleng District

This research was motivated by a phenomenon in the district of Buleleng related to the number of LPD with conditions that are less healthy to jammed has increased. In addition, the number of LPD that are stuck in Buleleng regency is the highest in Bali. The purpose of this study is to determine the implications of the internal control system and credit policy on the credit settlement strategy, the settlement of bad loans is settled by the principle of “Pang Pada Payu”. The number of samples in this study were 60 LPD selected based on the stratified random sampling method. The data analysis technique used in this study was a structural equation model (seminal structural modeling) based on variance or component based sem with smartpls 3.0 analysis tools. Based on the results of testing the internal control system has a significant positive effect on the strategy of settlement bad loans “Pang Pade Payu” Bad Loans Strategy in LPD in Buleleng Regency. Both credit policies have a significant positive effect on the strategy of settlement bad loans “Pang Pade Payu” Bad Loans Strategy in Village Credit Institutions in Buleleng Regency. Copyright © Universitas Pendidikan Ganesha. All rights reserved. * Corresponding author. E-mail addresses: nimadesriayuni90@gmail.com (Ni Made Sri Ayuni) A R T I C L E I N F O Article history: Received 19 August 2019 Received in revised form 16 September 2019 Accepted 15 October 2019 Available online 26 November 2019
Human adipose-derived mesenchymal stem cells accelerate decellularized neobladder regeneration

Abstract Decellularized natural bladder matrices (neobladders) represent an exciting means to regenerate the bladder following bladder cancer-associated cystectomy. In this study, we compare the evolution of decellularized matrices with recellularized matrices by seeding it with human adipose-derived mesenchymal stem cells (ADSC) after implantation following partial cystectomy in rats. We discovered significant anatomical differences since 10 days after neobladder implantation with the ADSC-containing matrices promoting a significant recovery of mature p63- and cytokeratin 7-positive urothelium. We also discovered significantly induced expression of the vimentin mesoderm marker in the submucosal layer in ADSC-seeded matrices. Interestingly, we found a higher expression of smooth muscle actin in transversal and longitudinal smooth muscle layers with ADSC-seeded matrices. Furthermore, ADSC also showed increased vascularization and nerve innervation of the neobladder as determined by the distribution of CD31 and S100β reactivity, respectively. We believe that ADSC and their paracrine-acting pro-regenerative secretome within decellularized matrices represent an efficient bladder substitution strategy; however, we require a fuller understanding of the mechanisms involved before clinical studies can begin.
Exploring Targeted Contrast-Enhanced Ultrasound to Detect Neural Inflammation

Targeted contrast-enhanced ultrasound (TCEUS) is an innovative method of molecular imaging used for detection of inflammatory biomarkers in vivo. By targeting ultrasound contrast to cell adhesion molecules (CAMs), which are known inflammatory markers within neural tissue, a more direct evaluation of neural inflammation can be made. Due to the novel nature of TCEUS, standardized methods of image analysis do not yet exist. Time intensity curve (TIC) shape analysis is currently used in magnetic resonance contrast imaging to determine temporal behavior of perfusion. Therefore, the presented research attempts to determine TIC shape analysis utility in TCEUS imaging by applying it to TCEUS scans targeted to CAMs present in neural inflammation. This was done in an animal model that underwent a traumatic spinal cord injury to induce inflammation (n = 31). Subjects were divided into four groups, each receiving a TCEUS targeted to a different CAM seven days after surgery (P-selectin, intracellular adhesion molecule 1 [ICAM-1], vascular cell adhesion molecule 1 [VCAM-1], and control). TICs were generated using average pixel intensity within the injured region of the spinal cord. TIC shape analysis found similar curves were produced while targeting P-selectin and VCAM-1, both demonstrating rapid and sustained enhancement. Control injections demonstrated no enhancement. ICAM-1 injections demonstrated limited enhancement and a shape similar to the control.
A Wearable Mechatronic Device for Hand Tremor Monitoring and Suppression: Development and Evaluation

Tremor, one of the most disabling symptoms of Parkinson’s disease (PD), significantly affects the quality of life of the individuals who suffer from it. These people live with difficulties with fine motor tasks, such as eating and writing, and suffer from social embarrassment. Traditional medicines are often ineffective, and surgery is highly invasive and risky. The emergence of wearable technology facilitates an externally worn mechatronic tremor suppression device as a potential alternative approach for tremor management. However, no device has been developed for the suppression of finger tremor that has been validated on a human. It has been reported in the literature that tremor can be selectively suppressed by mechanical loading. Therefore, the objectives of this thesis were to develop a wearable tremor suppression device that can suppress tremor at the wrist and the fingers, and to evaluate it on individuals with PD in a pre-clinical trial. To address these objectives, several experiments were performed to quantify hand tremor; an enhanced high-order tremor estimator was developed and evaluated for tremor estimation; and a wearable tremor suppression glove (WTSG) was developed to suppress tremor in the index finger metacarpophalangeal (MCP) joint, the thumb MCP joint, and the wrist. A total of 18 individuals with PD were recruited for characterizing tremor. The frequencies and magnitudes of the linear acceleration, angular velocity, and angular displacement of tremor in the index finger MCP joint, the thumb MCP joint, and the wrist were quantified. The results showed that parkinsonian tremor consists of multiple harmonics, and that the second and third harmonics cannot be ignored. With the knowledge of the tremor characteristics, an enhanced high-order tremor estimator was developed to acquire better tremor estimation accuracy than its lower-order counterpart.
An investigation of the effectiveness of professional learning activities for physics teachers in Saudi Arabia

This thesis addressed the issue of professional learning activities for teachers as an important factor that may affect students’ achievement in physics. It is recognised that it is not the only one. Other factors that could influence students’ achievements include availability and use of learning resources, classroom size and climate, family background characteristics, and students’ attitudes toward physics. Professional development can play a vital role in helping teachers to improve their teaching skills, knowledge and competencies. However, research shows that many professional development programs have failed to improve teaching practice (Birman, Desimone, Porter & Garet, 2000; Newmann, King, & Youngs, 2001; Armour & Yelling, 2004; Hofman & Dijkstra, 2010). This is also the case in Saudi Arabia for physics teachers where there are many opportunities for training and professional development, but these are not being reflected in student achievement. As seen in the disparity of results, with Saudi Arabian students in secondary schools obtained a low mean score in physics compared with chemistry, biology and geology (Educational Information Centre, 2010). This lack of training effectiveness may occur due to: poor analysis of teacher training needs (Alnooijm, 2005; Abo Atwan, 2008); failing to provide teachers with appropriate content during training courses (Kildan, Ibret, Pektas, Aydinozu, Incikabi, & Recepoglu, 2013); or trainers’ not being adequately skilled (Mansour, 2003; Al-Shehri, 2006). Such deficiencies reinforce that more effective approaches, such as Guskey’s (2002) five levels of Continuing Professional Development (CPD) and Transformative Professional Development (TPD) (Johnson & Fargo, 2010), should be drawn upon to inform training approaches.
Spiders (Arachnida: Araneae) in organic apple (Rosaceae) orchards in southeastern France

Abstract The role of spiders (Arachnida: Araneae) in biological control programmes has received less attention than that of insect natural enemies. The aim of this two-year study was to obtain descriptive data on spider spring field population structure and dynamics. The study was carried out in one insecticide-free and four organic apple orchards in southeastern France. Rolls and bands of corrugated cardboard near the ground and shoots infested with Dysaphis plantaginea (Passerini) (Hemiptera: Aphididae) in the tree canopy were used to sample spiders. Thirty-three spider species belonging to 14 families were identified from both sampling methods. Cheiracanthium mildei Koch (Araneae: Cheiracanthiidae) was clearly the predominant arboreal spider species in aphid-infested shoots (>57%). More than half of the spiders recorded in cardboard bands belonged to three species Drassodes pubescens (Thorell) (Araneae: Gnaphosidae), Pseudeuophrys erratica (Walckenaer) (Araneae: Salticidae), and Icius hamatus (Koch) (Araneae: Salticidae). Salticidae (39.9%) and Gnaphosidae (23.4%) families dominated significantly the spider assemblages observed in the cardboard rolls and were present on almost all sampling dates. However, in the two shelter types, the spider abundance curve clearly had a poly-modal shape. This may be due to the sequential arrival of some spider species or their dominance in a certain period of our study.
Ordinary and Slow Earthquakes Reproduced in a Simple Continuum System With Stochastic Temporal Stress Fluctuations

Earthquakes are complex and diverse, ranging from energetic and destructive megathrust earthquakes to slow earthquakes. Complex earthquake rupture processes are generally modeled by prescribing a deterministic system and solving deterministic differential equations. However, such approaches cannot adequately capture the temporal evolution of a complex fault system because of the inherent unpredictability that results from various unprescribed processes. Such unpredictability may be better represented by time‐dependent stochastic fluctuations in addition to the deterministic estimates. Here, we demonstrate that the consideration of time‐dependent stochastic stress fluctuations in ordinary crack simulations can reproduce a variety of ruptures, including both crack‐like and pulse‐like ordinary (fast) earthquakes and slow earthquakes, by simply changing the strength drop and the initial stress level. The results indicate that stochasticity is effective for reproducing and better understanding the diversity of earthquakes, including slow earthquakes.
CORRELATION BETWEEN INTRA-ABDOMINAL PRESSURE AND C- REACTIVE PROTEIN IN ACUTE PANCREATITIS

This study aimed at establishing the predictive value of the markers CRP and IAP within 48 hours from admission in patients with acute pancreatitis and to compare their predictive value. In our study, we used CRP values at 48 hours after admission, as a predictive marker for the evolution to SAP and we compared them with IAP at 48 hours and with Ranson and APACHE II scores also calculated at 48 hours. We used ROC curves for representation and comparison of APACHE II score, Ranson score, CRP and IAP at 48 hours after admission and for determining their value as predictors of progression to severe acute pancreatitis.