Miracle-dz/UniFAR-FTUs huggingface dataset:
A one parameter fit for glassy dynamics as a quantum corollary of the liquid to solid transition

We apply microcanonical ensemble considerations to suggest that, whenever it may thermalise, a general disorder-free many-body Hamiltonian of a typical atomic system has solid-like eigenstates at low energies and fluid-type (and gaseous, plasma) eigenstates associated with energy densities exceeding those present in the melting (and, respectively, higher energy) transition(s). In particular, the lowest energy density at which the eigenstates of such a clean many body atomic system undergo a non-analytic change is that of the melting (or freezing) transition. We invoke this observation to analyse the evolution of a liquid upon supercooling (i.e. cooling rapidly enough to avoid solidification below the freezing temperature). Expanding the wavefunction of a supercooled liquid in the complete eigenbasis of the many-body Hamiltonian, only the higher energy liquid-type eigenstates contribute significantly to measurable hydrodynamic relaxations (e.g. those probed by viscosity) while static thermodynamic observables become weighted averages over both solid- and liquid-type eigenstates. Consequently, when extrapolated to low temperatures, hydrodynamic relaxation times of deeply supercooled liquids (i.e. glasses) may seem to diverge at nearly the same temperature at which the extrapolated entropy of the supercooled liquid becomes that of the solid. In this formal quantum framework, the increasingly sluggish (and spatially heterogeneous) dynamics in supercooled liquids as their temperature is lowered stems from the existence of the single non-analytic change of the eigenstates of the clean many-body Hamiltonian at the equilibrium melting transition present in low energy solid-type eigenstates. We derive a single (possibly computable) dimensionless parameter fit to the viscosity and suggest other testable predictions of our approach.
Trans*-Sexualität neu denken: Eine partizipative Interviewstudie zu gelingender Sexualität ohne Genitalangleichung

Zusammenfassung Einleitung Studien zur Sexualität von trans* Personen sind häufig durch das heteronormative Bias geprägt, alle trans* Personen würden eine Genitalangleichung anstreben, um penil-vaginalen penetrativen Geschlechtsverkehr ausüben zu können, als (trans*) Mann in der insertiven, als (trans*) Frau in der aufnehmenden Rolle. Diese Studie untersucht erstmals die Sexualität von trans* Personen, die keine Genitalangleichung anstreben und mit ihrer Sexualität zufrieden sind. Forschungsziele Ziel der Studie ist es, die individuelle Sexualität von Menschen dieser Personengruppe zu beleuchten und die intrapsychischen, interaktionellen und kollektiven Ressourcen zu analysieren, auf die sie dabei zurückgreifen. Darunter fallen auch Strategien, um den scheinbaren Widerspruch von Geschlechtsidentität und Körperlichkeit zu überbrücken. Methoden Es wurden sechs leitfadengestützte qualitative Interviews durchgeführt und mithilfe einer inhaltlich strukturierenden qualitativen Inhaltsanalyse ausgewertet. Die Studie beinhaltete verschiedene partizipative Elemente. So wurden die Ergebnisse im Rahmen einer partizipativen Feedbackschleife durch die Teilnehmenden kommunikativ validiert. Ergebnisse Die Teilnehmer_innen berichten von vielfältigen, genitalen wie non-genitalen sexuellen Praktiken, die unabhängig von den damit assoziierten Geschlechterrollen stattfinden. Dabei greifen sie auf verschiedene Ressourcen und Strategien zurück. Insbesondere wird die geschlechtsanzeigende Funktion von Genitalien auf drei Ebenen dekonstruiert: individuell durch die Teilnehmenden selbst, interaktionell über die Anerkennung ihrer Geschlechtsidentität durch sexuelle Partner_innen und kollektiv durch die Communitys, in denen sie sich bewegen. Schlussfolgerung Die Studie entkräftet die oft unhinterfragte Vorannahme, dass trans* Personen per se ihre Genitalien nur widerwillig oder unter Erfahrungen von körperlicher Dysphorie in der Sexualität einsetzen. Mit den richtigen Ressourcen müssen sexuelle Rolle, Genitalienstatus und Geschlechtsidentität nicht stereotyp zusammenfallen, um gelingende Sexualität zu praktizieren.
Early life thermal stress modulates hepatic expression of thermotolerance related genes and physiological responses in two rabbit breeds

Abstract There are few data about early thermal conditioning (TC) and its effect on later life in rabbits. Therefore, the present study aimed to investigate the impact of exposing two rabbit breeds to early age short-term heat stress (EA-STHS) on physiological parameters and hepatic expression levels of some genes. Rabbits from New Zealand White (NZW) and Baladi Black (BB) rabbit breeds were reared in a controlled environmental chamber (28 ± 2 °C and 40 ± 2% RH). At 42 days of age, rabbits from both breeds were equally divided into two groups; control (untreated) and heat exposed groups (kept at 36 ± 1 °C and 62% RH for 6 h). At 13 weeks of age, rabbits of all groups were re-exposed to acute heat stress (36 ± 1 °C and 62% RH for 6 h). At 13 weeks of age, plasma CORT, plasma MDA, and hepatic MDA had significantly lower levels in the rabbits from the two breeds subjected to EA-STHS than untreated control groups. plasma TAC and the relative hepatic expression of all the studied genes like Hsp70, HspA9, Hsp90α and UCP2 had significantly higher levels in EA-STHS treated NZW and BB rabbits compared with the control groups. In conclusion, the results suggest that EA-STHS has a long-lasting effect on the later life response to acute heat stress in NZW and BB breeds, as indicated by the hepatic expression profile of several genes, corticosterone, and antioxidant parameters. Additionally, each breed had characteristic patterns for the tested parameters at each time point and treatment. HIGHLIGHTS Rabbits are susceptible to thermal stress, which is associated with adverse effects on production and reproduction traits. Early-age thermal conditioning is one of the suggested protective treatments to reduce the heat stress adverse effects. Early age short-term thermal stress may induce thermotolerance ability to later time heat exposure in both rabbit breeds.
The Genetics Conceptual Understanding of Indonesian and United States Undergraduate Biology Students

Genetics as a core concept of life science is essential for understanding biology. Examining genetics understanding among biology majors is becoming important since they must necessarily achieve some level of genetics understanding to advance their career. This study compares Indonesian biology majors’ genetics understanding with previously published data from students in the United States (US). This study also identifies the effect of academic year and program on genetics understanding by administering the Genetics Concept Assessment (GCA) to 377 biology majors in Indonesia. IRT-Rasch modeling was performed for instrument validation, followed by one-way ANOVA and independent sample t-test for the analysis. The results showed that Indonesian biology majors’ genetics understanding was significantly affected by academic year but was not affected by the academic program. Indonesian biology majors had a slightly similar level of genetics understanding with US non-majors’ pre-test scores, while Indonesian biology majors’ scores were two times lower than US majors’ post-test scores. The implications of reducing the gap between two countries are discussed.
Heterogeneity between Core Needle Biopsy and Synchronous Axillary Lymph Node Metastases in Early Breast Cancer Patients—A Comparison of HER2, Estrogen and Progesterone Receptor Expression Profiles during Primary Treatment Regime

Simple Summary All initial therapeutic decisions in early breast cancer are commonly based on the intrinsic subtype consisting of estrogen (ER), progesterone (PR), the human epidermal growth factor 2 (HER2) receptors and the proliferation marker Ki67. However, breast cancer is a very heterogeneous disease, and receptor expression is reported to change during progression. Little is known about receptor changes at the primary site. In a German single center study, we retrospectively analyzed a mostly therapy naive cohort of 215 primary breast cancer patients with axillary synchronous lymph node metastases (LNM). We compared core needle biopsy tissue of the primary tumor (t-CNB) to axillary LNM and detected receptor discordance for all three receptors at the primary site. Abstract In breast cancer therapeutic decisions are based on the expression of estrogen (ER), progesterone (PR), the human epidermal growth factor 2 (HER2) receptors and the proliferation marker Ki67. However, only little is known concerning heterogeneity between the primary tumor and axillary lymph node metastases (LNM) in the primary site. We retrospectively analyzed receptor profiles of 215 early breast cancer patients with axillary synchronous LNM. Of our cohort, 69% were therapy naive and did not receive neoadjuvant treatment. Using immunohistochemistry, receptor status and Ki67 were compared between core needle biopsy of the tumor (t-CNB) and axillary LNM obtained during surgery. The discordance rates between t-CNB and axillary LNM were 12% for HER2, 6% for ER and 20% for PR. Receptor discordance appears to already occur at the primary site. Receptor losses might play a role concerning overtreatment concomitant with adverse drug effects, while receptor gains might be an option for additional targeted or endocrine therapy. Hence, not only receptor profiles of the tumor tissue but also of the synchronous axillary LNM should be considered in the choice of treatment.
Young South Asians With ST-Elevation Myocardial Infarction (STEMI) – Outcomes, Clinical and Angiographic Profiles.

Background: Why STEMI in young South Asians (SAs) has more adverse outcomes compared to elder population is underexplored. We conducted this study to learn about common risk factors, disease patterns and prognostic factors in this population.Methods: It was an observational study from 2013-2019 done at the Aga Khan University Hospital, Karachi, Pakistan, a tertiary care hospital. Patients aged <45 years who presented with their first episode of ST elevated Myocardial Infarction (STEMI) and who underwent Primay PCI were included. Patients with previous MI or revascularization were excluded. Details of risk factors, lesion complexity and outcomes were noted. Main outcome measures were:i. Primary outcome of 30 day All-cause mortalityii. Secondary outcomes: (a) Composite of Shock/CPR/VT/Vfib, (b) Ejection fraction <35%, (c) Delayed discharge >5 daysResults: Of a total of 1207 patients, only 165 patients (13%) were <45 years old. Common risk factors included male gender 90.3%, n=149, obesity in 48.3%, n=69, history of tobacco in 45%, n=74 and positive family history in 48.4%, n=80. LAD was the culprit in 77.0%, n=127 with Single vessel disease (SVCAD) in 68%, n=112. Primary outcome of 30 day All-cause mortality was seen in 3.6%, n=6 patients. Secondary outcomes: (i) Composite of Shock/CPR/VT/Vfib was seen in 12%, n=20 associated to initial SBP <110 mmhg (OR 4.1, 95% CI 1.2-13.4) or heart failure (OR 3.5, 95% CI 1.0-12.6). (ii) Ejection fraction <35% was seen in 29%. n=48 associated to anterior infarction (OR 5.0, 95% CI 1.8-13.5 ), Time to hospital (TTH) >4 hours (OR 2.6, 95% CI 1.0-6.7) and heart failure (OR 5.1, 95% CI 1.7-15.4). (iii) Delayed discharge >5 days was seen in 27.3%, n=45 associated to TTH >4 hours (OR 3.8, 95% CI 1.3-11.2), the Composite of Shock/CPR/VT/VF (OR 6.4, 95% CI 1.9-21.6) and HTN (OR 2.1, 95% CI 1.0-5.2). Conclusion: Young SAs with STEMI are usually obese, tobacco-users with positive family history. LAD is the most common culprit vessel. Anterior STEMI, delayed presentation, initial SBP, and heart failure may help stratify these patients.
Effectiveness of the Portugal 2020 Programme: A Study from the Citizens’ Perspective

The European Structural and Investment Funds (ESIF) are the main instrument of the European Union (EU) Cohesion Policy to promote convergence, economic growth and reduce imbalances between EU members. The objectives of the 2014–2020 programming period follow the agenda of the Europe 2020 Strategy to promote smart, sustainable and inclusive growth of EU members. Since before joining the EU, in 1986, until the end of the Portugal 2020 Partnership Agreement (PT2020), Portugal will have received more than EUR 130 billion. Have the subsidies that Portugal has received been well applied? Our study fills a gap in the literature by portraying citizens’ perceptions about the effectiveness of EU funds for the development of the country and its regions. The study is quantitative in nature, and a non-probabilistic sample of 1119 participants answered our survey. A high proportion (76%) of the respondents considered that EU funds contributed to the development of the region where they live, although a significant percentage of the respondents (more than half) considered that there may be corruption in Portugal. The Portuguese also mentioned the existence of practices such as favouritism and lobbying regarding the approval of projects. Our findings are supported by the literature, which refers to “lost opportunities” in the inefficient application of ESIF, while recognising that EU funds have played a significant role in Portugal’s development over the last three decades.
Pesticide Usage: Attitudes and Practices among Rural Farmers in South India

Background: The major occupational diseases in India are occupational accidents, pneumoconiosis, musculoskeletal injuries, pesticide poisoning, and work place stress. Despite of low consumption of pesticides on global scale, cases of pesticide poising among Indian farmers are increasing every year. The reasons are many so in this study we wanted to assess the famers’ attitudes and practices about pesticide usage in rural areas of north Karnataka. Methods: A field based cross sectional study was conducted in the rural areas of Karnataka state Gadag district. Farmer’s, attitudes and practices about pesticide usage and its harmful effects on human health was assessed. A pre-tested semi-structured questionnaire was used to obtain the data from January to February 2020. Data were collected at the rural settings by visiting their house and agriculture fields. Results: Totally 265 farmers were interviewed, out of that Almost all of them have good attitudes about pesticide usage, impacts on environment and only 40% of them have good practices about the pesticide usage. Conclusion: Majority of the Farmers have good attitudes and practices about pesticide usage. Nearly more than half of the participants have poor practices in personal protective equipment’s usage while spraying the pesticide.
Intersection theorems for generalized weak KKM set‐valued mappings with applications in optimization

In this paper, we introduce the concept of generalized weak KKM mapping that is more general than many others encountered in the KKM theory. Then, two previous intersection theorems of the author are extended from weak KKM mappings to generalized weak KKM mappings. Applications of these results to set‐valued equilibrium problems and minimax inequalities are given in the last two sections.
Inhalational Bacteriophage and Nanosilver Effectiveness on nCOVID-19: A Case Report

This is a case report of an immunocompromised plus (nCOVID-19) infected elderly Iraqi man in the AL-KARAMA respiratory care unit. Consequently, this man presented on 2/6/2020 following accelerated respiratory deterioration over two days with positive PCR and CT scan confirmation. Ordinarily, SPO2 84% at room temp despite the oxygen administration 4 L/min, not intubated. Therefore, the physician staged this case as IIb according to clinical staging for nCOVID-19. Moreover, he had uncontrolled IDDM and right nephrectomy for renal cell carcinoma before three years. Although, the physician applied nCOVID-19 guidelines of the ministry of Health-Iraq for three days but without a response. So, the researchers added an Inhalational Bacteriophage solution to an Inhalational Nanosilver colloid (designated by the authors) alternative after patient consent. Interestingly, there were fast and notable improvements in the patient's overall health plus relief of the respiratory symptoms. Consequently, a continuous increase in his SPO2 over the next day approaching 97%. Moreover, an improvement in his speaking and walking commencing to discharge well plus a negative PCR. Thus, the Inhalational Bacteriophage and Nanosilver are the most beneficial treatment including the prevention of nCOVID-19 complications in all stages.
Validation of a TAM Extension in Agriculture: Exploring the Determinants of Acceptance of an e-Learning Platform

Supporting education and training initiatives has been identified as an effective way to address Sustainable Development Challenges. In this sense, e-learning stands out as one of the most viable alternatives considering its advantages in terms of resources, time management, and geographical location. Understanding the reasons that move users to adopt these technologies is critical for achieving the desired social objectives. The Technology Acceptance Model (TAM) provides valuable guidelines to identify the variables shaping users’ acceptance of innovations. The present study aims to validate a TAM extension designed for FARMER 4.0, an e-learning application in the agricultural sector. Findings suggest that content quality (CQ) is the primary determinant of farmers’ and agricultural entrepreneurs’ perception of the tool’s usefulness (PU). Furthermore, experience (EXP) and self-efficacy (SE) shape potential users’ perceptions about ease of use (PEOU). This study offers helpful insight into the design and development of e-learning applications in the farming sector and provides empirical evidence of TAM’s validity to assess technology acceptance.
Inoculant and urea-molasses additives for forage sorghum silage

Inoculant (1177 in one trial) and non-protein nitrogen (LSA-100 in two trials) silage additives were evaluated with whole-plant forage sorghum silage. Steers fed LSA-100 silage gained faster than steers fed control silage supplemented with soybean meal (4.8% in trial 1; 12% in trial 2). Feed conversion was improved 11% in trial 1 and was similar to the control silage in trial 2. Silage inoculated with 1177 supported rates and efficiencies of gain similar to the control silage. Of the nitrogen added from LSA-100, 90.9% in trial 1 and 86.2% in trial 2 was recovered from the concrete stave silos. Dry matter recoveries averaged 6.0 percentage units less for LSA-100 silages than controls, however 1177 increased recovery by 2.65 units. In general, silage from the bottom half of each silo was far more stable in air than that from the top half. The additives did not consistently affect aerobic stability.
Increase in secondary organic aerosol in an urban environment

Abstract. The evolution of fine aerosol (PM1) species as well as the contribution of potential sources to the total organic aerosol (OA) at an urban background site in Barcelona, in the western Mediterranean basin (WMB) was investigated. For this purpose, a quadrupole aerosol chemical speciation monitor (Q-ACSM) was deployed to acquire real-time measurements for two 1-year periods: May 2014–May 2015 (period A) and September 2017–October 2018 (period B). Total PM1 concentrations showed a slight decrease (from 10.1 to 9.6 µg m−3 from A to B), although the relative contribution of inorganic and organic compounds varied significantly. Regarding inorganic compounds, SO42-, black carbon (BC) and NH4+ showed a significant decrease from period A to B (−21 %, −18 % and −9 %, respectively), whilst NO3- concentrations were higher in B (+8 %). Source apportionment revealed OA contained 46 % and 70 % secondary OA (SOA) in periods A and B, respectively. Two secondary oxygenated OA sources (OOA) were differentiated by their oxidation status (i.e. ageing): less oxidized (LO-OOA) and more oxidized (MO-OOA). Disregarding winter periods, when LO-OOA production was not favoured, LO-OOA transformation into MO-OOA was found to be more effective in period B. The lowest LO-OOA-to-MO-OOA ratio, excluding winter, was in September–October 2018 (0.65), implying an accumulation of aged OA after the high temperature and solar radiation conditions in the summer season. In addition to temperature, SOA (sum of OOA factors) was enhanced by exposure to NOx-polluted ambient and other pollutants, especially to O3 and during afternoon hours. The anthropogenic primary OA sources identified, cooking-related OA (COA), hydrocarbon-like OA (HOA), and biomass burning OA (BBOA), decreased from period A to B in both absolute concentrations and relative contribution (as a whole, 44 % and 30 %, respectively). However, their concentrations and proportion to OA grew rapidly during highly polluted episodes. The influence of certain atmospheric episodes on OA sources was also assessed. Both SOA factors were boosted with long- and medium-range circulations, especially those coming from inland Europe and the Mediterranean (triggering mainly MO-OOA) and summer breeze-driven regional circulation (mainly LO-OOA). In contrast, POA was enhanced either during air-renewal episodes or stagnation anticyclonic events.
Effectiveness of Project-Based Learning Models in Improving Students' Creativity (A Literature Review)

The learning process on the 2013 curriculum uses a scientific approach that emphasizes students' activity in learning (student-centered learning). Learning that uses a scientific approach needs to be supported by the appropriate model and method. Project-based learning is one of the suggested learning models in the 2013 curriculum (K13). This learning model is designed to engage students in investigating real-world problems in their learning. Project-based learning drives teaching and learning, involves students in the learning process, motivates, and enhances the creativity of students. Hence, project-based learning is the appropriate learning model to improve students' creativity because it requires the students to be directly involved in their learning. Besides, students will also be more interested in learning because the problems used are related to their environment. Thus, the purpose of this paper is sharing the effectiveness of project-based learning model in improving students' creativity.
ABORIGINAL VERSUS NON‐ABORIGINAL ALCOHOLICS IN AN ALCOHOL WITHDRAWAL UNIT

Fifty‐five Aboriginal alcoholic males were compared with ninety non‐Aboriginal alcoholic males, presenting voluntarily for treatment at an alcohol withdrawal unit. Although the chronological development of excessive drinking habits was similar, significant differences in drinking patterns and social backgrounds were found. Aboriginal patients consumed more alcohol, had lower levels of educational and vocational achievement and were more often homeless. However, physical condition was similar in both groups. It was suggested that treatment of both groups should be similar in the acute withdrawal phase and that there was need for more rehabilitation and after‐care facilities for Aboriginal alcoholics rather than for more medical units.