Miracle-dz/UniFAR-FTUs huggingface dataset:
Effects of nursing intervention based on a positive motivational model on cardiac function, self-management and quality of life in elderly patients with coronary heart disease.

OBJECTIVE The aim of this study was to analyze the effects of nursing intervention based on a positive motivational model on cardiac function, self-management, and life quality in elderly patients with coronary heart disease (CHD). PATIENTS AND METHODS A total of 112 elderly CHD patients were picked as the subjects of this research from August 2021 to August 2022. All patients were randomized to the observation group and regular group by a two-color sampling method, with 56 cases in each group. Subjects in the regular group and observation group received traditional interventions and additional positive motivational model nursing interventions, respectively. The cardiac function [left ventricular ejection fraction (LVEF), left ventricular end-systolic diameter (LVESD), left ventricular end-diastolic diameter (LVEDD)], sports endurance, self-management ability, psychological status [depression self-assessment scale (SDS), anxiety self-assessment scale (SAS)], and life quality before and after the intervention were compared between two groups. The readiness for discharge scores and satisfaction with nursing care were compared between the two groups after the intervention. RESULTS After the intervention, the LVEF levels of the patients in both groups were elevated, and the LVESD and LVEDD levels were sharply decreased (p < 0.05). The improvement in cardiac function indexes was more evident in the observation group than in the regular group (p < 0.001). The readiness for discharge score of patients was markedly higher in the observation group than in the regular group (p < 0.01). After the intervention, the self-management score and sports endurance score of patients in both groups were evidently elevated (p < 0.05), which were much higher in the observation group than in the control (p < 0.001). The nursing satisfaction of patients in the observation group was 92.86%, much higher than 73.21% in the regular group (p < 0.05). The observation group had much lower SDS and SAS scores than the regular group after the intervention (p < 0.001). After the intervention, the observation group had a much higher life quality score than the regular group (p < 0.001). CONCLUSIONS The nursing intervention model based on the positive motivation model could significantly improve the cardiac function, discharge readiness, sports endurance, and self-management behavior of elderly patients with CHD, thereby improving their quality of life and achieving higher patient satisfaction.
The urban climate of Mexico City

spannungen fiihren iiber sie hinaus direkt zum Haupt zentrum. Ihre Entwicklung wird von zentrifugalen Kraften der Ballungskerne gesteuert. Sie wachsen, jedoch nicht aus eigener Kraft sondern als Satelliten. Demgegenuber steht die sich eigenstandig verstar kende regionale Vormacht der Prafektur-Hauptorte, die echte Regionalzentren geworden sind. Sobald es ihnen gelang, konkurrierende Nachbarstadte funktio nal zu iiberschichten und grofienmafiig zu iiberholen, wuchs und wachst ihr Vorsprung unaufhaltsam wei ter. Das ist Aomori gegeniiber Hirosaki erst halb, Sap poro gegeniiber Asahikawa und Otaru bereits voll ge lungen. Mentalitat und Wanderungsverhalten der ja panischen Bevolkerung unterstutzen den Prozefi der Selbstverstarkung, der das Modell des ? Grofien To kyo" auf verschiedene ? Klein-Tokyos" im ganzen Land ubertragt.
The transcription factor DUX4 orchestrates translational reprogramming by broadly suppressing translation efficiency and promoting expression of DUX4-induced mRNAs

Translational control is critical for cell fate transitions during development, lineage specification, and tumorigenesis. Here, we show that the transcription factor double homeobox protein 4 (DUX4), and its previously characterized transcriptional program, broadly regulates translation to change the cellular proteome. DUX4 is a key regulator of zygotic genome activation in human embryos, whereas misexpression of DUX4 causes facioscapulohumeral muscular dystrophy (FSHD) and is associated with MHC-I suppression and immune evasion in cancer. We report that translation initiation and elongation factors are disrupted downstream of DUX4 expression in human myoblasts. Genome-wide translation profiling identified mRNAs susceptible to DUX4-induced translation inhibition, including those encoding antigen presentation factors and muscle lineage proteins, while DUX4-induced mRNAs were robustly translated. Endogenous expression of DUX4 in human FSHD myotubes and cancer cell lines also correlated with reduced protein synthesis and MHC-I presentation. Our findings reveal that DUX4 orchestrates cell state conversion by suppressing the cellular proteome while maintaining translation of DUX4-induced mRNAs to promote an early developmental program.
Pukepuke Fonua: an exploratory study on the faikava as an identity marker for New Zealand-born Tongan males in Auckland, New Zealand

Based on my Master’s thesis, this paper is an exploratory study of the experiences and perceptions of a group of NZ-born Tongan males living in Auckland on what participation in the Tongan cultural of the faikava meant to them, how they valued this experience and whether they believed participation could help minimise some of the social pressures Tongan youth face today – such as alcohol and drug abuse and youth gang affiliation. Reports indicate that a factor in NZ-born Pacific Island youth engaging in these and other risky behaviours in New Zealand is their lack of cultural identity and security. For this study, the methodological framework of phenomenology and talanoa was employed involving individual talanoa with 12 participants who were members of faikava clubs in the Auckland region. These clubs were mainly linked to churches, villages and old boys associations. The talanoa were conducted in Tongan and English which was recorded. Findings were that the faikava played a significant role in teaching and reinforcing the pukepuke fonua or maintaining the Tonga culture and language for this group. In fact, they referred to the faikava as a cultural classroom where through engagement in debates, songs and music, they learnt, rejuvenated and maintained the Tongan culture and language. In sum, the faikava was a supplementary education site. In addition, the faikava also fostered intergenerational harmony, as the elders passed on customary knowledge. They also listened to the views of these younger participants. Finally for this group, the faikava had served as a diversion from alcohol consumption and affiliation with youth gangs. All 12 participants affirmed the value of the faikava and hope that this would be maintained in the future. On the basis of the results of this research, it can be concluded that the faikava is serving as an identity marker for NZ-born Tongan males today as a situation where the Tongan language and culture is learnt, reinforced and maintained. As this study does not represent the total population of NZ-born Tongan males living in the Auckland area, further research is warranted.
Use of Isotropic Stress State Framework to Evaluate the Effect of Suction on Some Mechanical Parameters of Sainte-Rosalie Clay Submitted to Confined Compression

This paper reports experimental data gathered while performing isotropic tests on a heavy agricultural clay soil from Quebec province (Eastern Canada). Tests performed were onedimensional compression, isotropic compression, and K0. Tests on saturated soil samples were performed using conventional procedures; tests on unsaturated samples were performed after the desired suction was applied to the samples. Samples used in all the tests were processed at the same suction before the selected suction was applied. For the one-dimensional compression tests, the chosen suction was applied by moistening or drying while the axis translation method was used for applying suction to soil samples in isotropic compression and K0 tests. Results show that soil plastic and elastic parameters are suction dependant. In addition, strength of Sainte-Rosalie clay measured under different suctions in K0 tests quantified the significant strength gain observed in the field when this material evolves from wet to dry conditions.
Fractal, predictability index and variability in trends analysis of river-water dynamics

ABSTRACT Statistical modelling, analysis of physico-chemical parameters chemical oxygen demand (COD), biochemical oxygen demand (BOD), dissolved oxygen (DO), water temperature (WT), free ammonia (AMM), total Kjeldahl nitrogen (TKN), total coliform (TC), fecal coliform (FC) and potential of hydrogen (pH) monitored at the Hathnikund barrage (Haryana) sample site of river Yamuna in India have been studied. It has been observed that water-quality parameters such as COD-BOD, AMM-TKN, WT-pH and TC-FC are positively correlated whereas COD-DO, BOD-DO, TKN-FC and DO-WT are negatively correlated. For water-quality parameters such as pH, AMM, TC and FC no seasonal pattern is observed. Parameters such as COD, BOD, TKN, DO and WT follow a six-month seasonal pattern. All the parameters except DO and WT follow a positive trend for monthly and annual variations. BOD, AMM and TKN have anti-persistence behaviour for both monthly and yearly variations. For parameters COD (+27.83%), BOD (+42.36%), AMM (+49.63%), TKN (+22.71%), TC (+141.80%) and FC (+42.89%) the future trend remains positive with high variability. WT (−7.47%) follows a negative trend with low variation and DO (−17.12%) has a negative trend with lofty variation. Using fractal, predictability index and variability in trend analysis, it is concluded that all parameters, except pH and WT, cross the prescribed limits of WHO/EPA and if the same trend should be followed, then in the future the quality of water shall continuously deteriorate and water may not be fit for drinking, agriculture and industrial use.
Political Connections and Business Strategy: The Impact of Types and Destinations of Political Ties on Business Diversification in Closed and Open Political Economic

This paper studies how different types and destinations of connections between business leaders and political actors create strategic benefits in closed and open political economic systems. The analysis examines how political ties facilitate diversification by business groups in Taiwan between 1986 and 1998, before and after the country underwent extensive political and economic liberalization that led to changes in diffusion of power, tie accountability, and public scrutiny. We show that formal position interlocks with the dominant party or senior government officials provide the greatest strategic benefits in a closed political economic system, while informal social ties to a wider range of political actors provide greater strategic benefits when a political economic system becomes more open.
Different sedation profiles with ciprofol compared to propofol represented by objective sedation level assessments by BIS and its acute hemodynamic impact in 3 escalated doses of ciprofol and propofol in healthy subjects: a single-center, open-label, randomized, 2-stage, 2-way crossover trial.

OBJECTIVE To compare the sedation profiles and the pharmacokinetic, pharmacodynamic and safety characteristics of ciprofol and propofol at 3 escalated dose levels in healthy Chinese male subjects. PATIENTS AND METHODS Eighteen subjects were planned to be enrolled into 3 dose groups in turn: group 1 (ciprofol-0.4 mg/kg vs. propofol-2.0 mg/kg), group 2 (ciprofol-0.6 mg/kg vs. propofol-3.0 mg/kg) and group 3 (ciprofol-0.8 mg/kg vs. propofol-4.0 mg/kg). They were randomly assigned into a ciprofol or propofol group in a ratio of 1:1, with sequences of ciprofol-propofol or propofol-ciprofol, separated with a washout period of at least 48 h. RESULTS A total of 19 subjects were enrolled and 18 completed the trial. The median time to being fully alert after induction by ciprofol was longer than for propofol. The bispectral index (BIS) recovered significantly slower with ciprofol than with propofol 5 min and 10 min after reaching its lowest points. Systolic blood pressure (group 1: p=0.041; group 2: p=0.015; group 3: p=0.004) and mean arterial pressures (group 1: p=0.026; group 2: p=0.015; group 3: p=0.004) measured by the area under the curve below the baseline during the 2 min after induction were significantly less for ciprofol compared to propofol, but a significant change in diastolic blood pressure was only observed in group 3 (p=0.002). Eighteen (100.0%) subjects experienced 47 ciprofol-related treatment emergent adverse events (TEAEs) and 17 (94.4%) subjects had 54 propofol-related TEAEs, which were mainly hypotension, involuntary movements, respiratory depression, and pain at the injection site with severity of grade 1 or 2. CONCLUSIONS Ciprofol may be well tolerated at higher doses in the clinical practice and exhibited significantly different sedation profiles to propofol.
Quantifying the Dynamic Evolution of Graded Gravel Beds Using Particle Tracking Velocimetry

AbstractThe motion of graded gravels under steady and spatially uniform turbulent flow is investigated in laboratory conditions using particle tracking velocimetry (PTV). The gravel bed is subjected to flows approaching critical armor velocity, and water worked until static armor is reached. A digital particle tracking (DPT) algorithm, based on image subtraction between subsequent frames, is developed and applied on the particle scale as the graded gravel bed is water-worked. The dynamic evolution of graded gravels is quantified continuously for up to 8 h. Characteristics of particle motion are identified, and movement patterns under complex flow conditions are analyzed. Particle tracking is applied to low-frequency (0.67-fps) and high-frequency (30-fps) data. This study provides a new perspective on gravel particle transport distances, trajectory sinuosity, sediment transport rate, fractional sediment transport rates, particle movement patterns, and instantaneous particle velocities.
Common Cancer Types and Risk of Stroke and Bleeding in Patients With Nonvalvular Atrial Fibrillation: A Population‐Based Study in England

Background The association between cancer and stroke or bleeding outcomes in atrial fibrillation is unclear. We sought to examine how certain types of cancer influence the balance between stroke and bleeding risk in patients with nonvalvular atrial fibrillation (NVAF). Methods and Results We estimated stroke and bleeding risk among adult patients with NVAF and certain types of cancer (breast, prostate, colorectal, lung, and hematological cancer) from 2009 to 2019 based on data from the UK Clinical Practice Research Datalink GOLD and Aurum databases. The control group included patients with NVAF only. Of 177 065 patients with NVAF, 11379 (6.4%) had cancer (1691 breast, 3955 prostate, 1666 colorectal, 2491 hematological, and 1576 lung). Compared with patients without cancer, stroke risk was higher in patients with breast cancer (adjusted hazard ratio [aHR], 1.20 [95% CI, 1.07–1.35) and with prostate cancer (aHR, 1.11 [95% CI, 1.01–1.12) if diagnosed within 6 months before NVAF. The risk of bleeding was increased in subjects with hematological cancer (aHR, 1.55 [95% CI, 1.40–1.71]), lung cancer (aHR, 1.49 [95% CI, 1.25, 1.77]), prostate cancer (aHR, 1.38 [95% CI, 1.28–1.49]), and colorectal cancer (aHR, 1.36 [95% CI, 1.21–1.53]), but not for subjects with breast cancer. The more recent the cancer diagnosis before NVAF diagnosis (within 6 months), the higher the risk of bleeding. Conclusions Breast and prostate cancer are associated with increased stroke risk, whereas in some cancer types, the risk of bleeding seemed to exceed stroke risk. In these patients, prescribing of oral anticoagulant should be carefully evaluated to balance bleeding and stroke risk.
Geomorphology of the Colorado River in the Grand Canyon

Sediment supplied to the Colorado River within the Grand Canyon has been sorted into distinct deposits of three grain size ranges. The major rapids are formed by boulder deposits from side-canyon tributaries. As a result of a fourfold reduction in peak discharge when Glen Canyon Dam was closed in 1963, new fan debris may increase the gradient through some of the rapids by a factor of 1.8. Cobbles and gravel, transported only during flood stages, are preferentially deposited in the wider sections of the river as bars and riffles and are, for the most part, inactive during post-dam discharges. Fine-grain (largely sandy) terraces occur throughout the canyon, especially along the banks of the large reverse eddies above and below the rapids. The lower terraces are being reworked into beach-like shores by diurnally-varying, post-dam discharges. A slight net lateral erosion of the terraces has resulted. Prior to construction of the dam, sandy bed deposits underwent scour averaging about 1 m during spring floods, balanced by deposition from tributary sources during the summer. Downstream from rapids, decreased turbulence due to lower discharges has resulted in deposition averaging 2.2 m on the bed within the upper portions of the canyon. Differences in rock types along the river determine overall channel morphology. Rocks of low resistance result in a wide valley, a meandering channel, and abundant cobble bars and sand terraces. Narrow channels with rapids and deep pools are most frequent within the sections of the canyon where Precambrian crystalline rocks dominate.
Coupled ocean‐atmosphere response to north tropical Atlantic SST: Tropical Atlantic dipole and ENSO

The coupled ocean‐atmosphere response to changes of the north tropical Atlantic (NTA) SST is investigated using a coupled ocean‐atmosphere general circulation model. The model explicitly demonstrates that a NTA SST anomaly can organize an inter‐hemispheric SST dipole in boreal spring over both the tropical Atlantic and eastern tropical Pacific primarily through a coupled wind‐evaporative‐SST (WES) feedback. While the tropical Atlantic dipole eventually decays in summer and fall, the eastern tropical Pacific dipole subsequently evolves into an ENSO‐like pattern through the seasonal migration of the ITCZ and coupled ocean‐atmosphere feedbacks.
Assessment of the quantitative and qualitative buffer function of an alluvial wetland: hydrological modelling of a large floodplain (Garonne River, France)

For 2 years, water flow‐patterns in the Garonne floodplain of south‐western France were studied in the field and through hydrodynamic modelling (MARTHE Hydrodynamic Software developed by BRGM). Water flow‐paths and the transport of dissolved elements between river and aquifer have been investigated and modelled. In order to quantify the buffer function of the alluvial floodplain, we focused our work on the effect of a major flood on the water flow‐direction, and on nitrate transport. Thus, we showed that the effect of a large flood in the river was rapidly lost with increasing distance from the river. During the observation period, a hydrologically active strip only 300 m wide on either side of the riverbed played a buffering role in absorbing the flood crest. It was also found that meanders favour the exchange between river and alluvial aquifer, shown by the creation of bypasses between the upstream and downstream parts of meanders. This, in turn, contributes to a dilution of nitrates in the phreatic aquifer, which here has higher nitrate content than the surface water; such dilution may result in an overestimation of the denitrification process in the wooded riverbanks. The coupling of chemical measurements—especially of chlorides and nitrate—with modelling of the dissolved‐element transport allows us to establish the water balance for the riparian wetland, and to separate the effect of dilution and denitrification on nitrate concentration. This indicated the existence of areas in the riparian wetlands where denitrification is particularly strong, leading to reductions in nitrate concentrations of 10 to 30 mg/l NO3− during the flood. Copyright © 2003 John Wiley & Sons, Ltd.
A model investigation of turbulence‐driven pressure‐pumping effects on the rate of diffusion of CO2, N2O, and CH4 through layered snowpacks

Pressure pumping at the Earth's surface is caused by short-period atmospheric turbulence, longer-period barometric changes, and quasi-static pressure fields induced by wind blowing across irregular topography. These naturally occurring atmospheric pressure variations induce periodic fluctuations in airflow through snowpacks, soils, and any other porous media at the Earth's surface. Consequently, the uptake or release of trace gases from soils and snowpacks is a combination of molecular diffusion and advection forced by pressure pumping. Using model-estimated fluxes, this study attempts to quantify the influence that turbulent pressure fluctuations with periods between 0.1 and 1000 s can have on the rate of exchange of CO2, N2O, and CH4 through a seasonal snowpack. Data for this study were collected at a forested subalpine meadow site in the Rocky Mountains of southern Wyoming, during February 1995 when the snowpack was distinctly layered and approximately 1.4 m deep. The data include mole fraction of CO2, N2O, and CH4 just above and at the base of the snowpack, several profiles of CO2, N2O, and CH4 mole fraction in the top l m of the snowpack, and a profile of snowpack density and tortuosity. Turbulent atmospheric pressure-pumping fluctuations, sampled at approximately 11 Hz for several hours, were obtained with a fast response differential pressure sensor. A one-dimensional steady state diffusion model and one- and three-dimensional time-dependent pressure-pumping models are used to estimate the gas fluxes through the snowpack. Boundary conditions are provided by grab samples just above the snowpack and at the soil/snow interface. The pressure-pumping models are driven by the observed pressure fluctuations, and all models include the observed layering of the snowpack. As with previous studies the present results indicate that the effects of pressure pumping are diminished with increasingly strong gradients. Furthermore, we conclude that unless pressure pumping influences the gas concentrations at the boundaries of the snowpack, it appears unlikely that it can significantly impact the rate of gaseous diffusion through the snowpack. Even two- and three-dimensional effects, which can have a significant short-term impact on the fluxes and concentration profiles, are nearly eliminated when averaged over a period of hours. It is also suggested that vertical layering is important for three-dimensional pressure-pumping studies and that the time-dependent temperature term, which is traditionally ignored when modeling dynamic pressure variations, may in fact be dominant in some situations and probably should be incorporated in future modeling studies of pressure pumping.
M-44 SODIUM CYANIDE EJECTORS IN THE ANIMAL DAMAGE CONTROL PROGRAM, 1976-1986

Author(s): Connolly, Guy E. | Abstract: This paper summarizes Animal Damage Control (ADC) program records relating to M-44 use during Fiscal Years 1976-86. During these years, M-44s were used in 14 western states to take 103,255 animals, including 92,843 coyotes, 5,544 other target canids, and 4,868 nontarget animals. More animals were taken in Texas than in all other states combined. Program-wide during FY 1977-81, M-44 effort averaged approximately 5,600 unit years annually and 1.2 target animals were recovered per M-44 year. M-44s accounted for 12.3 percent of all coyotes taken by the ADC program during FY 1976-86. The coyote take by M-44s doubled from FY 1981 through 1986. In FY 1986, more coyotes were taken by M-44s than by any other method in Texas, New Mexico, and Nebraska. Program-wide in that year, aerial hunting ranked first, the leghold trap second, and the M-44 third in numbers of coyotes taken. The M-44 has increased in importance since its reregistration in 1971, but the coyote lake by M-44 has not approached the peak reached in 1971.