Miracle-dz/UniFAR-FTUs huggingface dataset:
FVE-novel: Recovering Draft Genomes of Novel Viruses and Phages in Metagenomic Data

Background Despite the recent surge of viral metagenomic studies, recovering complete virus/phage genomes from metagenomic data is still extremely difficult and most viral contigs generated from de novo assembly programs are highly fragmented, posing serious challenges to downstream analysis and inference. Results Here we develop FVE-novel, a computational pipeline for reconstructing complete or near-complete viral draft genomes from metagenomic data. FVE-novel deploys FastViromeExplorer to efficiently map metagenomic reads to viral reference genomes or contigs, performs de novo assembly of the mapped reads to generate scaffolds, and extends the scaffolds via iterative assembly to produce final viral scaffolds. We applied FVE-novel to an ocean metagenomic sample and obtained 268 viral scaffolds that potentially come from novel viruses. Through manual examination and validation of the ten longest scaffolds, we successfully recovered four complete viral genomes, two are novel as they cannot be found in the existing databases and the other two are related to known phages. Conclusions The hybrid reference-based and de novo assembly approach used by FVE-novel represents a powerful new approach for exploring viral diversity in metagenomic data. FVE-novel is freely available at https://github.com/saima-tithi/FVE-novel .
Influence of Elevated CO2 and Municipal Wastewater Feed on the Productivity, Morphology, and Chemical Composition of Arthrospira (Spirulina) platensis

In this work, a marine strain of Arthrospira (Spirulina) platensis (CCMP1925) was submitted to high concentrations of municipal wastewater (WW) and carbon dioxide (CO2). Under standard conditions (Zarrouk medium and optimal light), production reached 2.79 g/kg of culture after 8 days. Adding wastewater to the mixture led to an increased cell density reaching 3.29 g/kg below 40% wastewater, while above 40%, wastewater was shown to inhibit productivity. At an elevated CO2 concentration fed to the mixture, production reached 3.55 g/kg, although increasing the concentration of CO2 above 2% (v/v) was shown to inhibit the production of biomass. High concentrations of combined wastewater and CO2 were generally shown to be detrimental for the production of algal biomass. However, some synergetic effects were observed for the optimal cell density that was obtained after 5 days for a mixture involving 40% wastewater and 8% CO2, while after 8 days, the best results were obtained with a 40% WW mixture and 0% CO2. A c.
Westerdykella reniformis: A New Record from Field Soils in Korea

During a survey of fungal diversity in different provinces of South Korea in 2017, a new fungal isolate was discovered. This fungal isolate was identified as Westerdykella reniformis, based on its morphological characteristics and phylogenetic analysis, using internal transcribed spacer (ITS) and 28S ribosomal DNA (28S rDNA) sequence data. To our knowledge, W. reniformis has not previously been reported in South Korea. Thus, in this study, we report a new record of a species from the Dothideomycetes class in Korea, and provide a detailed description with morphological illustrations.
Cocuk ve Ergenlerde EMDR:
Travma Sonrasi Stres Bozuklugu Tedavisindeki Etkililigi Uzerine Bir Derleme

Anahtar kelimeler Göz hareketleriyle duyarsızlaştırma ve yeniden işleme (EMDR), travma, çocuk, psikoterapi Öz EMDR, birçok farklı psikoterapi yaklaşımının tekniklerini bir araya getiren ve zihinsel bilgi işleme süreçleri ile bedensel uyarımları eşleştirerek travmatik deneyimlerin olumsuz etkilerine karşı çok yönlü müdahale edilmesini sağlayan bir tedavi yöntemidir. EMDR başlangıçta bireysel olarak yetişkinlere uygulanmak üzere tasarlanmıştır, ancak daha sonra çocuklar, ergenler ve gruplarla yapılan çalışmalarda da kullanılan geniş çaplı bir tedavi uygulaması haline gelmiştir. Bu çalışmanın amacı, çocuklukta karşılaşılan travmatik deneyimleri olan ve travma sonrası stres belirtisi gösteren çocukların tedavisinde, EMDR kullanımına dair kuramsal çerçevenin ve geçmiş çalışmaların gözden geçirilmesidir. Çocuklukta meydana gelen travmatik deneyimlerin, yetişkinlikte birçok psikolojik rahatsızlığa ve davranış problemlerine sebep olduğu, yanı sıra çocuğun normal gelişim sürecinde aksamalara yol açtığı bilinmektedir. Çocuklarla yapılan çalışmalar, EMDR yönteminin kısa süreli uygulamalarda bile TSSB semptomlarının azaltılmasında ve psikolojik iyi oluşun desteklenmesinde etkili bir yöntem olduğunu göstermiştir. Bu yönüyle, çocuklarda travma tedavisi için EMDR kullanımının yaygınlaştırılmasının faydalı olabileceği düşünülmektedir. Bireysel ve toplumsal ruh sağlığı açısından, çocukların yaşadıkları olumsuz deneyimleri en aza indirmesi ve gelecek yaşamları için koruyucu bir müdahale olması nedeniyle EMDR yöntemi geçerli, etkili ve verimli bir tedavi yöntemi olarak görülmektedir.
Integrative characterization and validation of tumor-associated immune signature combined with immune-infiltration analysis in clear cell renal cell carcinoma

Background We aimed to explore and validate a prognostic immune signature for predicting the prognosis of ccRCC patients, combined with immune-infiltration analysis. Methods We obtained the multi-omics data from public datasets. Differential analysis was performed by edgeR package. Prognostic immune signature was identified by univariate Cox analysis, and we constructed an integrative tumor-associated immune Genes (TAIG) model from the multivariate Cox results. Functional analysis was conducted to uncover the related crosstalk. Importantly, we implemented the CIBERSORT algorithm to estimate the immune cell fractions in ccRCC samples and analyzed the differential abundance of tumor-infiltrating immune cells in two TAIG groups using Wilcoxon rank-sum test. The prognostic role of differential immune cells was further assessed by Kaplan-Meier analysis. In addition, we investigated the associations of single immune signature with specific immune cells. Results A total of 628 ccRCC patients were included in our integrative analysis, including 537 ccRCC patients in discovery group and 91 patients in validation group. Then, we identified the 14 key immune signatures. The AUC was 0.802 and patients with higher TAIG suffered from worse prognosis. Correlation analysis indicated that TAIG correlated tightly with clinical variables and TMB. Moreover, functional analysis also implicated the immune-related GO items or crosstalk. Therefore, we discovered the relationships of TAIG with tumor-infiltrating immune cells. The differential abundance of immune cells showed significant prognostic difference consisted of memory activated CD4 + T cell, T follicular helper cells, T regulatory cell, and so on. Moreover, we also characterized the associations between identified signature with specific immune cells. Finally, the 5-year AUC in ICGC cohort was 0.72, suggesting the robustness of TAIG that we constructed. Conclusions Totally, our team characterized the tumor-associated immune signature in ccRCC and further uncovered the prognostic tumor-infiltrating immune cells related with TAIG, providing a comprehensive foundation for investigating mechanisms or individualized immunotherapy.
In situ Crystallization of N(SiMe3)3 and As(SiMe3)3: Trigonal planar or pyramidal coordination of the central atoms?

Abstract In situ crystallization technique at low temperature was used to obtain single crystals of the low melting compounds N(SiMe3)3 1 and As(SiMe3)3 3. N(SiMe3)3 has a waxy consistence at room temperature. The solid-state structure of both compounds has been determined by single-crystal X-ray diffraction analysis. N(SiMe3)3 is distorted and shows nearly a trigonal planar coordination of the central nitrogen atom. In contrast, the heavier homologue As(SiMe3)3 shows a trigonal pyramidal coordination with Si-As-Si 103.4(6)°–104.9(6)°.
Selected determinants of the frequency of consuming particular food product groups among regional-level football referees

The aim of the study was to assess the frequency of consuming particular food groups among regional-level football referees depending on age, refereeing experience and sense of generalised self-efficacy. The study was conducted among a group of 138 male football referees from the Malopolska and Podkarpacie regions, using the authors’ own questionnaire on food consumption frequency and the Generalised Self-Efficacy Scale (GSES). It was shown that along with the age of the referees, the frequency of consuming fruit (p < 0.001), milk and dairy products with reduced fat content (p < 0.001), poultry and cold-cuts (p < 0.01) as well as nuts (p < 0.001) increased, while the frequency of consuming white cereal products (p < 0.001) and sea fish (p < 0.05) decreased. Along with refereeing experience, the frequency of eating fruit (p < 0.001), milk and dairy products with reduced fat content (p < 0.01), poultry meat and cold-cuts (p = 0.001), nuts (p < 0.001) and alcoholic beverages (p < 0.001) increased, while the frequency of consuming white cereal products (p < 0.001), sea fish (p < 0.05) and sweet carbonated drinks (p < 0.01) decreased. A positive correlation was found between the intensity of generalised self-efficacy and the frequency of consuming milk and dairy products with reduced fat content (p < 0.01), fermented dairy products (p < 0.01), eggs (p < 0.001) and mineral water (p < 0.001) as well as dry red wine (p < 0.05), and a negative correlation was noted with the frequency of consuming pork (p < 0.05), fast food products (p = 0.001) and sweetened carbonated beverages (p < 0.001). In the examined group of regional-level football referees, there was a tendency towards more rational nutrition choices along with age and refereeing experience as well as a sense of self-efficacy, while the most explicit trends regarded relationships with the sense of self-efficacy.
Hadamard well-posedness for a structure acoustic model with a supercritical source and damping terms

This article is concerned with Hadamard's well posedness of a structural acoustic model consisting of a semilinear wave equation defined on a smooth bounded domain \begin{document}$ \Omega\subset\mathbb{R}^3 $\end{document} which is strongly coupled with a Berger plate equation acting only on a flat part of the boundary of \begin{document}$ \Omega $\end{document} . The system is influenced by several competing forces. In particular, the source term acting on the wave equation is allowed to have a supercritical exponent, in the sense that its associated Nemytskii operators is not locally Lipschitz from \begin{document}$ H^1_{\Gamma_0}(\Omega) $\end{document} into \begin{document}$ L^2(\Omega) $\end{document} . By employing nonlinear semigroups and the theory of monotone operators, we obtain several results on the existence of local and global weak solutions. Moreover, we prove that such solutions depend continuously on the initial data, and uniqueness is obtained in two different scenarios.
The Effect of Work-Family Conflict and Social Support on Job Satisfaction: A Case Study of Female Employees in Indonesia

This study aimed to measure the effect of work-family conflict and social support (supervisor, peer, and family support) on the job satisfaction of the female employees of two private companies in Indonesia. Data collection was done by simple random sampling of 145 population of female employees. The returned and valid questionnaire results were 139 samples. Data processing was used SEM method with SmartPLS 3.0 software. The results of this study concluded that work-family conflict, peer support, and family support have a significant effect on job satisfaction. Meanwhile, supervisor support has not a significant effect on job satisfaction. This new research proposed a model for building job satisfaction among the private company employees in Indonesia through enhancing social support and manage work-family conflict.
Wellness Review 2020, Part 2

Introduction: This article comprises Part 2 of the Journal of Wellness review of 2020 wellness literature (July – December). In this review, JWellness editors continue the goal of offering a cohesive summary of recent publications within the wellness domain. We summarize new science and resilience initiatives published outside of JWellness that seek understanding of either burnout and its prevention or thriving in the medical community. Methods: From the interval of 01 July – 31 Dec 2020, PubMed was queried for empirical research studies, review articles, and editorials in accordance with the following algorithm: an article was required to have two delineating keywords, each from a separate grouping. The first identified medical professionals in either the title or the abstract: (“clinical professionals,” “physicians,” or “caregivers”), and the other identified a wellness-related keyword in the title: (“wellness,” “burnout,” “resilience,” or “resiliency”). Literature in Review: A total of 234 articles resulted. The list for inclusion was then narrowed to sixty-three articles plus one that was hand-picked. Recent literature into physician wellness, burnout and resilience continues to focus heavily on COVID-19. Well-researched topics include burnout surveillance, proposals for and small investigations into resilience, multiple studies attempting to differentiate characteristics that predispose to burnout, and the impact of the pandemic. Less has been written on leadership, financial wellness, and sustainable resilience-building initiatives. We note relatively few control-measured interventional studies—the majority of which remain small in endeavor and short in duration, limiting generalizability. Conclusion: Recent literature into physician wellness, burnout and resilience focuses heavily on COVID-19. Many workplace / organizational factors negatively influence wellness: cumbersome EHRs, cultures not focused on socialization and self-compassion, and high physician task load. We express optimism regarding future interventional studies of burnout mitigation and resilience enhancement.
Density Functional Theory Analysis of Metal/Graphene Systems As a Filter Membrane to Prevent CO Poisoning in Hydrogen Fuel Cells

Hydrogen fuel cells are a very promising potential replacement for internal combustion engines. However, their current use is limited by carbon monoxide poisoning of the platinum anode catalyst that occurs when CO enters the cell in the H2 feed gas. A novel new solution to this problem is the addition of a metal/graphene filter membrane exterior to the cell. This membrane will remove CO from the feed gas, allowing reduced loading of the expensive Pt catalyst and increasing cell lifetime. In the current work, density functional theory (DFT) was used to analyze graphene membranes containing nickel, copper, platinum, and iridium/gold atoms. The binding energy of the metal to the graphene was measured for a lone system and in the presence of CO and H2 to predict its durability. The binding energy of CO and H2 to metal was also measured to estimate its efficiency. All systems were analyzed using natural bond orbitals (NBOs). It was found that copper is a poor choice for use in membranes in all respects. Nickel.
A persistence‐based Wold‐type decomposition for stationary time series

This paper shows how to decompose weakly stationary time series into the sum, across time scales, of uncorrelated components associated with different degrees of persistence. In particular, we provide an Extended Wold Decomposition based on an isometric scaling operator that makes averages of process innovations. Thanks to the uncorrelatedness of components, our representation of a time series naturally induces a persistence‐based variance decomposition of any weakly stationary process. We provide two applications to show how the tools developed in this paper can shed new light on the determinants of the variability of economic and financial time series. Wold decomposition temporal aggregation persistence heterogeneity forecasting C18 C22 C50
Qualidade de sementes de feijão-azuki dessecadas com saflufenacil e submetidas ao armazenamento

The objective of this study was to evaluate the effect of using the herbicide saflufenacil desiccant pre-harvest and storage on the physiological and sanitary quality of azuki bean seeds. Six doses of saflufenacil herbicide (0, 50, 75, 100, 150 and 200 g a.i. ha-1) were tested and two evaluation periods of seed quality: harvest and six months after harvest. The desiccant application occurred at physiological maturity of azuki bean and seeds were stored in paper bags (kraft) under natural conditions - 25.4 ± 3 °C temperature and 67.3 ± 3% relative humidity. The saflufenacil may be used up to a dose of 65 g a.i. ha-1, without harming the physiological seed quality. The storage caused a drop in the percentage of germination, increase in the number of abnormal seedlings and reduction in size and dry mass of seedlings. Desiccation pre-harvest and storage reduces the infestation of Cladosporium, Fusarium and Rizhopus on the azuki bean seed.
Whole-body Vibration Attenuates Pyroptosis-Mediated Inflammation but Accelerates Progression of Intervertebral Disc Degeneration

Background Whole body vibration (WBV) is a non-pharmaceutical therapy that has been widely incorporated into clinical practice for musculoskeletal disorders, including low back pain (LBP). Intervertebral disc (IVD) degeneration (IVDD) is clinically associated with LBP and is known as the main cause for LBP. However, cumulative evidence also suggested WBV might have an adverse impact on IVDs. Moreover, previous studies have been focusing on the effects of WBV on healthy mice, rather than those suffering from IVDD. Thus, uncertainties still exist concerning the effects of WBV on IVDs undergoing IVDD. This study was aiming to evaluate the effects of WBV intervention on the development and progression of IVDD mouse model induced by lumbar spine instability (LSI) surgery. Methods LSI surgery, by resecting the lumbar 3 rd -5 th spinous processes along with the supraspinous and interspinous ligaments, was conducted in 10-week-old male mice which then received WBV treatment (1 h per day, 5 days per week, at 3 Hz with peak acceleration at 0.4 g) or sham treatment. The progression of IVDD was evaluated by MRI, μCT and histological analyses after WBV treatment. The matrix metabolism, distribution of sensory nerves, pyroptosis in IVDs tissues were determined by immunohistological analysis or real-time PCR. The apoptosis of IVD cells was detected by TUNEL assay. Results LSI surgery was successful in producing IVDD modeling. WBV caused decreases in IVD height and annulus fibrosus (AF) score, as well as increased numbers of apoptotic cells in IVD tissues. WBV contributed to sensory innervation into AF and upregulation of Adamts5 and MMP3 expression in IVDD mice received LSI surgery. In addition, WBV treatment triggered earlier activation of Wnt/β-catenin signaling in IVDD mice with WBV treatment compared with those without WBV treatment. Unexpectedly, WBV significantly attenuated Caspase-1 and IL-1β expression in AF. Conclusions Collectively, our findings demonstrate that WBV treatment may worsen the development of ongoing IVDD. Decrease of IL-1β expression after WBV intervention may partially account for patient self-reported pain relief after WBV treatment in some previous trials. This study may help us better understand the effects of WBV intervention on patients experiencing LBP resulting from the degeneration of lumbar IVDs.
Financial Reporting Quality and Dividend Policy: New Evidence from an International Level

This study examines the link between financial reporting quality and dividend payout across 123 countries. We find that financial reporting quality increases dividend payout after controlling for firm and country specifics. We also investigate different channels that mediate the relation between financial reporting quality and dividend payout. We find that the positive association between high-quality financial reporting and dividend payout is more pronounced when firms have free cash flow problems, face financial constraints, and are located in countries with greater minority shareholder protection rights. Conversely, firms benefit less from this positive relation when located in countries with higher accounting standards. The findings remain consistent after several robustness checks, thus highlighting the effectiveness of more transparent disclosure of financial information in reducing information asymmetry related to firms’ internal agency costs and their relationships with external parties.
Soil Microbiological Attributes Under Ecological Restoration Technologies in Subtropical Forest

To accelerate the recovery of degraded environments, it is necessary to use ecological restoration techniques, which require validation according to the ecosystem conditions where are implemented. This work aimed to evaluate soil microbiological attributes under different ecological restoration technologies in a subtropical forest. The study was conducted at UTFPR-DV, southwest of Paraná, in an ecotone between Mixed Ombrophilous Forest and Semideciduous Seasonal Forest and on an Oxisol. In December 2010, a tillage area of at least 17 years old was isolated and the passive restoration, tree planting and nucleation treatments were installed in 40x54 m plots and four replications. In November 2018 the soil was sampled in these plots and in a native forest area as a reference. There were calculated soil organic carbon content (OCC) and microbiological attributes such as microbial biomass N and C (NMIC and CMIC), basal respiration, fungal spore content and the metabolic (qCO2) and microbial quotient (MICq). It can be concluded that nucleation technology can restore soil microbiological attributes but has not yet reached the conditions of a natural environment. Passive restoration is not a good technology for restoring soil microbiological attributes. The higher contents of CMIC, NMIC, OCC, MICq and fungal spores in the soil under native forest compared to HIGHLIGHTS  Soil microbiological attributes are sensitive to evaluate soil quality in ecological restoration.  The recovery of soil microbiology is slow in areas under ecological restoration.  Changes in forest cover interfere in soil microbiological activity. 2 Rosa, G. F. ; et al. Brazilian Archives of Biology and Technology. Vol.63 no.spe: e20190651, 2020 www.scielo. br/babt ecological restoration technologies indicate that eight years of adoption of these techniques have not yet been enough to fully recover soil microbiological activity.