Miracle-dz/UniFAR-FTUs huggingface dataset:
Visualizing the Distribution of Jujube Metabolites at Different Maturity Stages Using Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry Imaging

Chinese jujube (also called Chinese date, Ziziphus jujuba Mill.) is an economically important tree in China and provides a rich source of sugars, vitamins, and bioactive components, all of which are indispensable and essential for the composition and participation in life processes of the human body. However, the location of these metabolites in jujube fruits has not been determined. This study applied matrix-assisted laser desorption/ionization mass spectrometry imaging (MALDI-MSI) to investigate the spatial distribution of sugars, organic acids, and other key components in jujube fruits at different developmental periods. Soluble sugars such as hexoses and sucrose/maltose significantly increase with fruit ripening, while organic acids show an overall trend of initially increasing and then decreasing. Procyanidins and rutin exhibit specific distributions in the fruit periphery and peel. These findings suggest that MALDI-MSI can be used to study the spatial distribution of nutritional components in jujube fruits, providing insights into the changes and spatial distribution of substances during jujube fruit development. This technique offers a scientific basis for jujube breeding, utilization, and production.
Nutritional and Shelf-Life Estimation of Nutritive Muffins Incorporating Dillenia indica and Terminalia Chebula Flour

The present study was undertaken to develop nutritive muffins using Dillenia indica and Terminalia chebula, evaluate their sensory attributes, nutrient content and conduct shelf-life studies. Three variations of muffins were developed and under each formulation, three different level of incorporations were made and compared to a control muffin. The developed muffins were evaluated for their sensory acceptability and the most preferred F2 formulation was selected and evaluated for proximate composition and shelf life. Developed nutritive muffins had been highly accepted in all attributes, is nutrient-dense, innovative and healthier snack but low shelf-life due to non-addition of any artificial preservative.
Multi-Omics of Familial Thoracic Aortic Aneurysm and Dissection: Calcium Transport Impairment Predisposes Aortas to Dissection

Several genetic defects, including a mutation in myosin heavy chain 11 (Myh11), are reported to cause familial thoracic aortic aneurysm and dissection (FTAAD). We recently showed that mice lacking K1256 of Myh11 developed aortic dissection when stimulated with angiotensin II, despite the absence of major pathological phenotypic abnormalities prior to stimulation. In this study, we used a comprehensive, data-driven, unbiased, multi-omics approach to find underlying changes in transcription and metabolism that predispose the aorta to dissection in mice harboring the Myh11 K1256del mutation. Pathway analysis of transcriptomes showed that genes involved in membrane transport were downregulated in homozygous mutant (Myh11ΔK/ΔK) aortas. Furthermore, expanding the analysis with metabolomics showed that two mechanisms that raise the cytosolic Ca2+ concentration—multiple calcium channel expression and ADP–ribose synthesis—were attenuated in Myh11ΔK/ΔK aortas. We suggest that the impairment of the Ca2+ influx attenuates aortic contraction and that suboptimal contraction predisposes the aorta to dissection.
Prevalence of Allergic Diseases and Risk Factors in Preschool Children

Allergic diseases are very common in children. The aim of this study is to obtain information about the frequency and risk factors of allergic diseases in kindergarten children aged 3-6 years. This study was carried out between 13.02. 2018 and 30.12. 2018 in kindergartens, in accordance with the ISAAC Phase I protocol for children aged 3-6 years. The study was carried out by distributing 3000 questionnaires in 20 kindergartens. 2001 out of 2040 collected questionnaires were included in the study. Of the participants, 986 (49.3%) were female and 1015 (50.7%) were male. The frequency of asthma symptoms was 30.4% (n=608). The frequency of allergic rhinitis symptoms was found to be 37.1% (743 people). The risk of asthma symptoms was significantly higher in males, those whose mothers smoked during pregnancy, those born preterm, those with a smoker at home and those with mold in the home (p
How Extracellular Nano-Vesicles Can Play a Role in Sepsis? An Evidence-Based Review of the Literature

Abstract Sepsis is a systemic inflammatory reaction caused by infection. Severe sepsis can lead to multiple organ dysfunction, with a high incidence rate and mortality. The molecular pathogenesis of sepsis is complex and diverse. In recent years, with further study of the role of extracellular vesicles (EVs) in inflammatory diseases, it has been found that EVs play a dual role in the imbalance of inflammatory response in sepsis. Due to the great advantages such as lower toxicity, lower immunogenicity compared with stem cells and better circulation stability, EVs are increasingly used for the diagnosis and treatment of sepsis. The roles of EVs in the pathogenesis, diagnosis and treatment of sepsis were summarized to guide further clinical studies.
Evaluation of sweet potato (Ipomoea batatas L.) performance and soilproperties under tillage methods and poultry manure levels

Research study on the effect of tillage systems and application rate of poultry manure on sweet potato (Ipomoea batatas) in Alfisol of southwest Nigeria is lacking. Field trials were conducted in 2006, 2007 and 2008 cropping seasons on an Alfisol (Oxic Tropuldalf) at Owo in rainforest zone of southwest Nigeria. The trials consisted of the factorial combinations of two tillage methods (manual clearing and conventional tillage) and four manure levels (0, 5, 10 and 15 t/ha) arranged in a randomized complete block design and replicated three times. Conventional tillage alone (CTo) resulted in lower soil N, P, K, Ca, Mg and soil organic C and better leaf N, P, K, Ca and Mg concentrations, growth and yield of sweet potato compared with manually cleared (MCo) plots. The better performance of sweet potato under conventional tillage (CTo) was adduced to reduced bulk density. Bulk density was negatively correlated with yield. Conventional tillage alone (CTo) improves sweet potato tuber yield by 62, 55 and 42% in 2006, 2007 and 2008, respectively compared with manual clearing alone (MCo). In both the manually cleared and conventionally tilled plots, soil organic C, N, P, K, Ca, Mg and water content increased with amount of poultry manure, while soil pH, bulk density and temperature were reduced. Yields given by 5, 10 and 15 t/ha poultry manure were not significantly different under both manually cleared and conventionally tilled treatments. Conventional tillage plus 5 t/ha poultry manure (CT+5 PM) produced the highest overall yield. Compared with manual clearing alone (MCo) and conventional tillage alone (CTo), conventional tillage plus 5 t/ha poultry manure (CT+5 PM) improved tuber yield of sweet potato by 117 and 43%, respectively. Therefore the use of 5 t/ha poultry manure with conventional tillage is recommended for sweet potato production on an Alfisol of southwest Nigeria.
Characterization of products of the early stages of pedogenesis in ornithogenic soil from Maritime Antarctica

Limited pedogenesis on the Antarctic continent results in unusual, but important, short‐range order inorganic phases and organo‐mineral complexes (both with broad peaks from X‐ray diffraction) in the clay fraction, which can be studied by sequential chemical extractions. We aimed to develop a better sequential extraction procedure to obtain more detailed discrimination of the short‐range order phases (SROP) of the clay fraction of soil from Maritime Antarctica. Selected chemical properties of the soil and clay fraction were related to different phases of these products. The total amount of SROP and organo‐mineral complexes in the clay fraction ranged from 15.1 to 43.9%, with greater occurrence in ornithogenic soil. The continuous incorporation of guano from penguins into the soil profile has contributed to increasing amounts of organo‐mineral complexes. Short‐range order phases have an important effect on soil chemical properties, such as an increase in non‐exchangeable acidity, quantity of hydroxyl groups on the surface of the colloidal fraction, the buffering capacity of Al3+ from non‐exchangeable and structural forms of the element, and a decrease in soil CEC. The greater number of sequential extraction steps enabled the separation of SROP and organo‐mineral complexes into two phases of stability, with a clear predominance of the more soluble forms.
Infrasound pulses from lightning and electrostatic field changes: Observation and discussion

Narrow (~1–2 s) infrasound pulses that followed, with ~11 to ~50 s delays, rapid changes of electrostatic field were observed by a microbarometer array in the Czech Republic during thunderstorm activity. A positive pressure fluctuation (compression phase) always preceded decompression; the compression was usually higher than the decompression. The angles of arrival (azimuth and elevation) were analyzed for selected distinct events. Comparisons of distances and azimuths of infrasound sources from the center of microbarometer array with lightning locations determined by the European Cooperation for Lighting Detection lightning detection network show that most of the selected events can be very likely associated with intracloud (IC) discharges. The preceding rapid changes of electrostatic field, their potential association with IC discharges, and high‐elevation angles of arrival for near infrasound sources indicate that an electrostatic mechanism is probably responsible for their generation. It is discussed that distinguishing the relative role of thermal and electrostatic mechanism is difficult and that none of the published models of electrostatic production of infrasound thunder can explain the presented observations precisely. A modification of the current models, based on consideration of at least two charged layers, is suggested. Further theoretical and experimental investigations are however needed to get a better description of the generation mechanism.
TOMATO FRUIT YIELD AND EVAPOTRANSPIRATION IN THE CONDITIONS OF SOUTH SERBIA

AKSIC, M. , S. GUDZIC, N. DELETIC, N. GUDZIC and S. STOJKOVIC, 2011. Tomato fruit yield and evapotranspiration in the conditions of South Serbia. Bulg. J. Agric. Sci., 17: 150-157 Water is a limited agricultural resource, so this study has been related to rational use of water in the intensive tomato growing technology. The two-year investigation was carried out by a biological procedure – through field trials in the conditions with irrigation of tomato hybrid Amati F 1 , on alluvium soil type, in the river valley of Southern Morava, near Nish. The experiments were set in random complete block design with four replications, where three irrigation variants were involved (SWP of 20 kPa, 30 kPa, 40 kPa) together with the unirrigated control. Observing both investigation years, the highest fruit yield was reached at the variant with SWP of 30 kPa, while in variants with higher (SWP of 20 kPa) and lower (SWP of 40 kPa) soil moisture fruit yield decreased. The greatest tomato fruit yield was observed when the average water consumption for ETP amounted 584 mm, so this value could be regarded as tomato’s demand for water in south Serbia. The highest values of WUE and IWUE for tomato were reached in the variant with SWP of 30 kPa, meaning rational water consumption was enabled at this SWP value. The study results have shown that, using tensiometer, tomato irrigation regime can be successfully kept at SWP of 30 kPa, on alluvium soil type in south Serbia.
Pure Isolated Internuclear Ophthalmoplegia as Presentation of Midbrain Ischemic Stroke: A Case Report

Internuclear ophthalmoplegia (INO) is a condition characterized by impaired ocular movement, leading to an inability to perform coordinated lateral gaze, resulting in ophthalmoplegia. This impairment results from damage to the medial longitudinal fasciculus (MLF), which can occur because of various types of lesions localized in the pons or midbrain. In this case, we report on a 67-year-old man with multiple comorbidities who arrived at the emergency department with complaints of sudden dizziness and an unsteady gait. During the examination, he exhibited left INO, which was characterized by limited left eye adduction and multidirectional nystagmus of the right eye when performing right lateral gaze.
Concentration of Heavy Metals in Sediment and Seagrasses Tissue of the Red Sea Coastal Water of the Sudan

The study investigated the concentration of Lead, Cadmium, Nickels and Chromium in sediment and seagrass tissues at six selected sites along the Su-danese Red Sea coast. The findings of the study added some important and necessary information about the status and condition of the coastal environment in the Sudanese Red Sea coast in terms of the extent of pollution with heavy metals. The study sites included: Marsa Bashayer, Marsa Dama Dama, Green Area, Shipyard, Marsa Halout and Dungonab Bay. The Atomic Absorption Spectrophotometer was used to measure Lead, Cadmium and Nick-els. The colorimetric detection method was used for Chromium using the Spectrophotometer. Marsa Dama Dama site revealed high levels concentration of heavy metals in sediment for Lead (60.5) µg/g, Cadmium (0.22) µg/g and Chromium (146.65) µg/g. Marsa Halout showed the highest mean concentration of Nickel in sediment at 14 µg/g. The variation of concentration of metals in sediment between the sites was not significant. The mean concentration of metals in seagrass species tissues ranged from 3.9 to 26.25 µg/g for Lead, 0.1 to 0.90 µg/g for Cadmium, 0.38 to 5.96 µg/g for Nickel and 0.15 to 0.495 µg/g for Chromium. The differences of concentration of heavy metals in seagrass tissues among the sites were significant for Lead and not significant
Short- and Long-Term Variability of Snow Albedo

The progress of snow albedo for the 1991 winter from Helligdagshaugen research site, Norway, is presented. The temporal reduction of albedo decreases as the snow undergoes a process of metamorphosis, as long as the snow depth is large enough to prevent absorption of solar radiation by the underlying terrain. Later, as the snow depth becomes less than about 10 cm and the area of bare patches grows, there is an increase in the temporal rate of reduction in albedo. An accumulated daily maximum temperature index is shown to be a good predictor of both the long-term development of the snow albedo and the daily mean albedo. The actual albedo deviates from the predicted long-term albedo due to variable meteorological conditions of which solar radiation is the most important one. Solar radiation and snow albedo are negatively correlated. Linear regression is performed for a winter period with no melting and for two distinct melting periods. Snow albedo was first determined as a function of temperature index alone. An improved accuracy of 2-6 per cent in estimated snow albedo was obtained when solar radiation was included. Very similar regression coefficients were found for two different periods.
Mutual Relations among Personal, Social and Organizational Factors in The Process of Education

The education process is most importantly aimed at optimal children’s development and their successful learning. School, thus, has a task to provide safety, underlying the clear rules of behaviour and zero tolerance for violence, and to create a positive and stimulating atmosphere. Such school approach is based on dynamic mutual relations among learners, their families, teachers, classes, the entire school, and a wider social context in which the school exists and operates. In a high-quality school, individual differences are accepted, and no one is excluded from the process of making more important decisions. Therefore, it is vital to see how much the school recognizes, encourages, and frees learners’ natural curiosity as well as their critical assessment of their own and social values. In order to contribute to creating a positive school atmosphere and thus encourage the learners’ progress and their wish to learn, this paper examines learners’ opinions about their own behaviour, satisfaction with school and ways of teaching, and the quality of family environment (a questionnaire has been designed for this purpose). The research was conducted in one primary school in the Zagreb area, including 114 seventh-and eighth-graders. To determine the grade-and gender-related differences, the non-parametric Mann-Whitney test was used for testing significance between two independent samples. With the purpose of creating a positive school atmosphere, mutual relations among learners’ personal and social, and the schools’ organizational factors have been analysed, and the results show a statistically significant difference in the learners’ opinions about the non-acceptable forms of behaviour, as well as the quality of the family environment, effective parenting, and the perception of personal and social development. There is a statistically significant difference between seventh-and eighth-graders in their self-assessments of the development of a positive responsible attitude towards their health and safety, ability to recognize the consequences of their own and others’ actions, acceptance of rules of cooperation, and attitudes about family environment. These results in the process of education raise additional questions that can serve to further elaborate the methodology and search for ways to develop self-evaluation and prevention programs in the future, making them a more efficient and effective approach to improving the overall school work
Randomized full‐waveform inversion: a dimenstionality‐reduction approach

Full-waveform inversion relies on the collection of large multiexperiment data volumes in combination with a sophisticated back-end to create high-fidelity inversion results. While improvements in acquisition and inversion have been extremely successful, the current trend of incessantly pushing for higher quality models in increasingly complicated regions of the Earth reveals fundamental shortcomings in our ability to handle increasing problem sizes numerically. Two main culprits can be identified. First, there is the so-called “curse of dimensionality” exemplified by Nyquist’s sampling criterion, which puts disproportionate strain on current acquisition and processing systems as the size and desired resolution increases. Secondly, there is the recent “departure from Moore’s law” that forces us to develop algorithms that are amenable to parallelization. In this paper, we discuss different strategies that address these issues via randomized dimensionality reduction.
Synthesis of graded CdS1−xSex nanoplatelet alloys and heterostructures from pairs of chalcogenoureas with tailored conversion reactivity

A mixture of N,N,N′-trisubstituted thiourea and cyclic N,N,N′,N′-tetrasubstituted selenourea precursors were used to synthesize three monolayer thick CdS1−xSex nanoplatelets in a single synthetic step. The microstructure of the nanoplatelets could be tuned from homogeneous alloys, to graded alloys to core/crown heterostructures depending on the relative conversion reactivity of the sulfur and selenium precursors. UV-visible absorption and photoluminescence spectroscopy and scanning transmission electron microscopy electron energy loss spectroscopy (STEM-EELS) images demonstrate that the elemental distribution is governed by the relative precursor conversion kinetics. Slow conversion kinetics produced nanoplatelets with larger lateral dimensions, behavior that is characteristic of precursor conversion limited growth kinetics. Across a 10-fold range of reactivity, CdS nanoplatelets have 4× smaller lateral dimensions than CdSe nanoplatelets grown under identical conversion kinetics. The difference in size is consistent with a rate of CdSe growth that is 4× greater than the rate of CdS. The influence of the relative sulfide and selenide growth rates, the duration of the nucleation phase, and the solute composition on the nanoplatelet microstructure are discussed.
Investigating doctors implementation of ACC/AHA blood cholesterol treatment recommendations at a tertiary hospital in Northern Saudi Arabia

Background: The 2018 American College of Cardiology (ACC) and American Heart Association (AHA) updated data on blood cholesterol treatment guidelines showed a significant shift in treating atherosclerotic cardiovascular disease (ASCVD). In 2018, recommendations were adopted to increase the number of persons using statin therapy. Still, real-world observations of how treatment use has changed, especially in Saudi Arabia, have yet to be limited in the literature. Doctors' implementation of ACC/AHA 2018 recommendations regarding prescribing medications has yet to be studied in Saudi Arabia. Aim: To examine doctors' implementation of ACC/AHA 2018 cholesterol recommendations in managing acute atherosclerotic cardiovascular disease patients. Results: Almost 47% of the patients were managed according to the 2018 ACC/AHA recommendations. However, 53% of patients did not take statins. Doctors adhered to the recommendations when working with patients with myocardial issues, in contrast to other events. Of the non-adherent patients, 40% refused the treatment because of their beliefs or fear of the side effects. Conclusion: Our primary analysis concluded that statin recommendations were not given to more than half of the patients with acute atherosclerotic diseases; moreover, some did not receive any statin therapy.
What does the general population think 'Dance and Health' needs to further develop?

In recent years, the interactive discipline of 'dance and health' has been demonstrated by researchers to have a positive effect on public health. However, further examination and identification of problems are needed in this context to improve 'dance and health'. 'Dance and health' in its form, population, and context, is influenced by the subjectivity of researchers in their practice projects, and more scientific and academic theories need to be constructed to fill the academic gap in this discipline. This research is based on the stance that 'dance and health' benefit the general public. By reviewing the existing literature to confirm the value function of 'dance and health', problems are identified, listening to the general public's views in this research, and further suggestions are made for future development of 'dance and health'.