Miracle-dz/UniFAR-FTUs huggingface dataset:
A Nonisolated DC–DC Boost Converter With High Voltage Gain and Balanced Output Voltage

This paper presents a dc-dc boost converter with high voltage gain based on the three-state switching cell for split-capacitor neutral-point-clamped inverters. The proposed converter is analyzed considering the operation in continuous conduction mode and duty cycle higher than 0.5, which corresponds to overlapping mode. The main characteristics of the topology are operation at high switching frequency, whereas the input inductor is designed for twice such frequency; in order to minimize weight and volume, the voltage stress across the switches is lower than half of the output voltage and naturally clamped by one output capacitor, allowing the use of MOSFET transistors with reduced intrinsic on-resistance; the input current presents small ripple; the output voltage can be further stepped up by increasing the transformer turns ratio without compromising the voltage stress across the switches; and the output voltage is naturally balanced, thus making the converter suitable for supplying split-capacitor inverters. Several topologies where a high voltage step-up is possible are initially investigated in the literature. Then, the principle of operation and experimental results for a 1-kW prototype are presented to validate the theoretical analysis and demonstrate the converter performance.
Changes in Precipitation-Runoff Relationship in Six Catchments of the Adriatic Coast of Central Italy

Besides climate change, human activities may introduce variability in the flow regime. Thus, investigation of the impacts of climate change and human activity on hydrology recently has become an important issue. In this paper hydrological data of six catchments in the coastal area of the Adriatic sea, in central Italy, were used to detect statistically significant trends and change points in annual rainfall and streamflow. Moreover, potential changes in precipitation-runoff relationship have been investigated and finally a quantitative evaluation of the effect of climate variability and human activities on runoff has been assessed separately, with the former individuated as the more influent.
Reduction of Quality (RoQ) attacks on structured peer-to-peer networks

In contrast to traditional brute-force attacks, RoQ (Reduction of Quality) attacks are periodic, stealthy, yet potent, which exploit the vulnerability of adaptation mechanisms to undermine certain services. As the application-level peer-to-peer (p2p) protocols depend on a recovery-adjustment process to maintain global consistency of routing information when peers join and leave the systems, we propose a novel breed of RoQ attacks in structured p2p systems: (1) We induce a general model for RoQ attacks, and then derive in structured p2p networks a new attack form that RoQ attackers periodically create concurrent failure through manipulation of massive nodes, degrading the system performance repeatedly. (2) We explore the impacts of RoQ attacks on Chord with detailed analysis and theoretical estimations, and confirm them by simulation results on p2psim, including successful lookup ratio and lookup latency. Moreover, we also discuss the detection and defense against such attacks and the improvements of protocols for attack tolerance.
New type of feeding transformer for AC railway traction system

At Shinkansen substations in Japan that receive electric power from an extra-high voltage system, we have been using modified Woodbridge connected transformers for traction power supply since the inauguration of the Sanyo Shinkansen, which commenced commercial operations in March 1972. However, this transformer is of a rather complicated structure. Therefore, we studied a new type of transformer, equipped with equal functions, however a simpler mechanism as compared with a conventional one. We termed the transformer a roof-delta connected transformer since it has a roof-winding and a delta-winding. The roof-delta connected transformer expectable to decrease costs by reducing quantity of winding. We fabricated roof-delta connected transformers for trial at 66kV-voltage. We performed various tests including measurement of neutral phase current. Test results revealed that this transformer is applicable to the used in AC traction feeding system. The first practical roof-delta connected transformer is going to be installed at a new Shinkansen substation constructed by JRTT. JR East is also planning at present to install them at existing Tohoku and Joetsu Shinkansen substations for their renewal. This paper describes the fundamental characteristics of the roof-delta connected transformer and the test results.
A SUB-ARCSECOND SURVEY TOWARD CLASS 0 PROTOSTARS IN PERSEUS: SEARCHING FOR SIGNATURES OF PROTOSTELLAR DISKS

We present a 1.3 mm dust continuum survey toward nine Class 0 protostars and two Class I protostars in the Perseus molecular cloud, using CARMA with a resolution of ∼0. ″3 (70 AU). This sample approximately doubles the number of Class 0 protostars observed with spatial resolutions <100 AU at millimeter wavelengths, enabling the presence of large protostellar disks and proto-binary systems to be probed. We have detected flattened structures with radii >100 AU around two sources (L1448 IRS2 and Per-emb-14), and these sources may be strong disk candidates. Marginally resolved structures within 30° of perpendicular to the outflow are found toward three protostars (L1448 IRS3C, IRAS 03282+3035, L1448C) and are considered disk candidates. Two others (L1448 IRS3B, IRAS 03292+3039) have complex resolved structures, possibly indicative of massive, fragmenting inner envelopes or disks; L1448 IRS3B also has evidence for a companion separated by 0. ″9 (∼210 AU). The candidate first hydrostatic core L1451-MMS is marginally resolved on 1″ scales and the Class 0 protostar IC 348-MMS and does not have strong indications of resolved structure at any scale. The strong disk candidate sources were followed up with C18O ( J = 2 → 1 ? > ) observations; we detect velocity gradients that are consistent with the expected rotation axis, but without enough sensitivity to determine if it is Keplerian. We compare the observed visibility amplitudes to radiative transfer models of protostellar envelopes and disks. The visibility amplitude ratios show that a compact component (possibly a disk) is necessary for five of nine Class 0 sources. An envelope-only scenario cannot be ruled out for the other four Class 0 sources. We conclude that there is evidence for the formation of large disks in the Class 0 phase, but Class 0 disks likely have a range of radii and masses that depend on the initial conditions of their parent cores.
Analysis of a class of k-dimensional merge procedures, with an application to 2d delaunay triangulation in expected linear time after two-directional sorting

This paper exploits the notion of \unnn-ished sites" in the average-case analysis of k-dimensional divide-and-conquer algorithms. This general result is then applied to the 2D case, and it is shown that the divide-and-conquer construction of the Delaunay triangulation of a set of planar points quasi-uniformly distributed in a square may be done in expected linear time after a two-directional preprocessing sort. This method is readily implemented, and, as shown by the easily reproduced results provided, it is one of the fastest worst-case optimal methods ever suggested to construct real-scale Delaunay triangulations in the plane.
Nonconvex One-bit Single-label Multi-label Learning

We study an extreme scenario in multi-label learning where each training instance is endowed with a single one-bit label out of multiple labels. We formulate this problem as a non-trivial special case of one-bit rank-one matrix sensing and develop an efficient non-convex algorithm based on alternating power iteration. The proposed algorithm is able to recover the underlying low-rank matrix model with linear convergence. For a rank-$k$ model with $d_1$ features and $d_2$ classes, the proposed algorithm achieves $O(\epsilon)$ recovery error after retrieving $O(k^{1.5}d_1 d_2/\epsilon)$ one-bit labels within $O(kd)$ memory. Our bound is nearly optimal in the order of $O(1/\epsilon)$. This significantly improves the state-of-the-art sampling complexity of one-bit multi-label learning. We perform experiments to verify our theory and evaluate the performance of the proposed algorithm.
HISTONE DEACETYLASE 6 Controls Gene Expression Patterning and DNA Methylation-Independent Euchromatic Silencing 1

To investigate the role of chromatin regulators in patterning gene expression, we employed a unique epigenetically controlled and highly tissue-specific green fluorescent protein reporter line in Arabidopsis (Arabidopsis thaliana). Using a combination of forward and reverse genetic approaches on this line, we show here that distinct epigenetic regulators are involved in silencing the transgene in different tissues. The forward genetic screen led to the identification of a novel HISTONE DEACETYLASE6 (HDA6) mutant allele (epigenetic control1, hda6-8). This allele differs from the previously reported alleles, as it did not affect DNA methylation and only had a very modest effect on the release of transposable elements and other heterochromatic transcripts. Overall, our data shows that HDA6 has at least two clearly separable activities in different genomic regions. In addition, we present an unexpected role for HDA6 in the control of DNA methylation at CG dinucleotides.
A Dual Ascent Framework for Lagrangean Decomposition of Combinatorial Problems

We propose a general dual ascent (message passing) framework for Lagrangean (dual) decomposition of combinatorial problems. Although methods of this type have shown their efficiency for a number of problems, so far there was no general algorithm applicable to multiple problem types. In this work, we propose such a general algorithm. It depends on several parameters, which can be used to optimize its performance in each particular setting. We demonstrate efficiency of our method on the graph matching and the multicut problems, where it outperforms state-of-the-art solvers including those based on the subgradient optimization and off-the-shelf linear programming solvers.
Oedichirus spelaeus n. sp., the first cave dwelling beetle from Madagascar (Coleoptera: Staphylinidae: Paederinae)

1Institute of Evolutionary Biology (CSIC-Universitat Pompeu Fabra), Barcelona, Spain 2MECADEV UMR 7179 MNHN/CNRS, Paris, France 34 rue du centre, Angaïs, France CCorresponding author: arnaud1140@yahoo.fr Abstract During an expedition of the French National Museum of Natural History in the Tsingy de Namoroka National Park, we systematically collected the cave fauna. Various mainly troglophilic species were found, but one of the most surprising discoveries was a Staphylinidae belonging to a new species and remarkable for its morphologic adaptations: reduced eyes, long antennae and legs, and depigmentation. This species is the first cavernicolous beetle described from Madagascar. A description of the new species is provided, as well as molecular data and details of the ecology of the species. A. Faille and J.C. Lecoq. Oedichirus spelaeus n. sp. , the first cave dwelling beetle from Madagascar (Coleoptera: Staphylinidae: Paederinae). Journal of Cave and Karst Studies, v. 80, no. 1, p. 13-18. DOI: 10.4311/2017LSC0112R2
Learning Ontologies to Improve the Quality of Automatic Web Service Matching

Automatically finding suitable Web services given a request is a difficult problem because the interface descriptions of Web services are often terse and cryptic. Dictionary and information retrieval based techniques have proven useful in disambiguating the semantics of service descriptions, but they are limited in their capability to consider the relationships between the words describing the Web services. Current ontology-based approaches typically require a user to explicitly create domain ontologies. This paper presents a novel technique that significantly improves the quality of semantic Web service matching by (1) automatically generating ontologies based on Web service descriptions and (2) using these ontologies to guide the mapping between Web services. Our approach differs from earlier work on service matching by considering the relationship between words rather than treating them as a bag of unrelated words. The experimental results indicate that with our unsupervised approach we can eliminate up to 70% of incorrect matches that are made by dictionary-based approaches.
Infection of HeLa cells with poliovirus results in modification of a complex that binds to the rRNA promoter

In HeLa cells, RNA polymerase I (Pol I)-mediated transcription is severely inhibited soon after infection with poliovirus. We have developed a gel retardation assay to analyze DNA-protein complexes formed at the Pol I promoter. We show here that two complexes (A and C) formed by nuclear extracts from uninfected cells disappear after infection of cells with poliovirus. In contrast, a new, rapidly migrating complex (D) is formed in virus-infected cell extract. This change in the mobility of gel-retarded complexes correlates well with the kinetics of inhibition of rRNA transcription in virus-infected cells. Incubation of nuclear extracts from mock-infected cells with bacterially expressed, purified poliovirus protease 3C results in the disappearance of complexes A and C with concomitant generation of complex D. A partially purified transcription factor fraction derived from uninfected cells that contains complex A is able to restore Pol I transcription when added to virus-infected cell extracts, suggesting that this complex plays an important role in Pol I transcription. These results suggest that poliovirus proteinase 3C may have an important role in the shutoff of Pol I transcription in cells infected with poliovirus.
Interacting with social networks of intelligent things and people in the world of gastronomy

This article introduces a framework for creating rich augmented environments based on a social web of intelligent things and people. We target outdoor environments, aiming to transform a region into a smart environment that can share its cultural heritage with people, promoting itself and its special qualities. Using the applications developed in the framework, people can interact with things, listen to the stories that these things tell them, and make their own contributions. The things are intelligent in the sense that they aggregate information provided by users and behave in a socially active way. They can autonomously establish social relationships on the basis of their properties and their interaction with users. Hence when a user gets in touch with a thing, she is also introduced to its social network consisting of other things and of users; she can navigate this network to discover and explore the world around the thing itself. Thus the system supports serendipitous navigation in a network of things and people that evolves according to the behavior of users. An innovative interaction model was defined that allows users to interact with objects in a natural, playful way using smartphones without the need for a specially created infrastructure. The framework was instantiated into a suite of applications called WantEat, in which objects from the domain of tourism and gastronomy (such as cheese wheels or bottles of wine) are taken as testimonials of the cultural roots of a region. WantEat includes an application that allows the definition and registration of things, a mobile application that allows users to interact with things, and an application that supports stakeholders in getting feedback about the things that they have registered in the system. WantEat was developed and tested in a real-world context which involved a region and gastronomy-related items from it (such as products, shops, restaurants, and recipes), through an early evaluation with stakeholders and a final evaluation with hundreds of users.
IRBIT is a novel regulator of ribonucleotide reductase in higher eukaryotes

Regulating DNA building blocks The bulding blocks of DNA, deoxynucleotide triphosphates, are synthesized by the enzyme ribonucleotide reductase (RNR). Its central role in DNA synthesis and its aberrant expression in tumors have made it an important anticancer target, but nucleoside analog inhibitors of RNR can have adverse side effects. Arnaoutov and Dasso identify IRBIT (IP3-receptor-binding protein released with inositol 1,4,5-trisphosphate) as an RNR-binding protein. IRBIT regulates the activity of RNR by stabilizing the inactive form bound to deoxyadenosine triphosphate in the low-affinity A site. In turn, phosophorylation of IRBIT regulates its RNR-binding activity. IRBIT provides a new target for RNR inhibition that might avoid some of the side effects of current drugs. Science, this issue p. 1512 A regulator of the enzyme that makes the building blocks of DNA provides a new target for anticancer drugs. Ribonucleotide reductase (RNR) supplies the balanced pools of deoxynucleotide triphosphates (dNTPs) necessary for DNA replication and maintenance of genomic integrity. RNR is subject to allosteric regulatory mechanisms in all eukaryotes, as well as to control by small protein inhibitors Sml1p and Spd1p in budding and fission yeast, respectively. Here, we show that the metazoan protein IRBIT forms a deoxyadenosine triphosphate (dATP)–dependent complex with RNR, which stabilizes dATP in the activity site of RNR and thus inhibits the enzyme. Formation of the RNR-IRBIT complex is regulated through phosphorylation of IRBIT, and ablation of IRBIT expression in HeLa cells causes imbalanced dNTP pools and altered cell cycle progression. We demonstrate a mechanism for RNR regulation in higher eukaryotes that acts by enhancing allosteric RNR inhibition by dATP.
One-step patterning of aligned nanowire arrays by programmed dip coating.

A fundamental step in the construction of nanowire devices is transfer of the nanowires from their stock to the substrate on top of which the device will be built. Therefore, alignment and controlled positioning of the nanowires are highly desirable, especially for the large-scale (e.g., on a 4-inch (10-cm) wafer) fabrication of parallel device arrays. Nanowires are normally synthesized and processed in solution. Therefore, any subsequent patterning technique would inevitably involve a dewetting step. Herein we show that nanowires can be aligned and selectively deposited at the edge of a drying droplet as a result of evaporation-induced capillary flow. This contact-line deposition can be regulated with a simple dip-coating setup to create massive nanowire arrays with predefined spacing and tunable wire density. It also enables the selective placement of the nanowire arrays directly onto prefabricated electrode arrays, thus providing a facile and inexpensive method for the large-scale fabrication of nanowire-based devices. Although it is possible to integrate nanowires directly into some specific device platforms during synthesis, it is more common to make nanowire devices starting from a nanowire suspension with a subsequent patterning process. A few methods have been developed to make aligned nanowire arrays on a substrate, for example, Langmuir–Blodgett, microfluidic, 7] electric-field-assisted assembly, and optical trapping. For all these patterning processes, nanowires are either made or processed within a solvent. As a result, any such technique would eventually encounter solvent evaporation before the final dried nanowire pattern is obtained. Therefore, it should be of great interest and technological importance to explore the full extent of the dewetting process for assembling nanostructures. 12] Herein we report our observation of contact-line deposition and alignment of nanowires in an evaporating droplet. These findings are then employed and tailored for large-scale patterning of nanowires by dip coating. Ring-shaped stains are often observed when a droplet of colloidal solution (e.g., coffee) is dried. An outward capillary flow of the solvent is necessary to compensate the loss of solvent at the perimeter, which also carries the dispersed materials to the solvent–substrate contact line and leads to highly selective deposition along the perimeter of the droplet. We have discovered that in a drying droplet containing nanowires, this capillary flow also sorts the nanowires along the radial direction (Figure 1a), especially when the solvent is volatile (e.g., methylene chloride or chloroform). Figure 1b shows a typical ring-shaped stain obtained from drying a droplet of nanowire dispersion in methylene
Tranexamic acid reduces perioperative blood loss of posterior lumbar surgery for stenosis or spondylolisthesis

Background: A prospective, randomized, double-blind, placebo-controlled study was performed. The routine usage of TA in spinal surgery is controversial. Only a few studies have focused on patients undergoing posterior lumbar surgery for stenosis or spondylolisthesis, although a large clinical cohort exists in the population. This study aimed to evaluate the effect and safety of TA in reducing perioperative blood loss in posterior lumbar surgery for stenosis or spondylolisthesis. Methods: 100 eligible patients out of 126 were randomized to receive either a bolus dose of 30 mg/kg TA i.v, a maintenance dosage of 2 mg/kg/h TA, or an equivalent volume of normal saline. The pedicle screw system was used for fixing in all the patients, followed by decompression and posterior lumbar interbody fusion. The primary outcomes were intraoperative estimated blood loss and total blood loss. The secondary outcomes were receiving packed red blood cells and postoperative hemoglobin and hematocrit levels. Results: In total, 4 patients were excluded from the analyses, 50 patients were in the TA group, and 46 in the placebo group. The demographic and baseline data between the groups were not statistically different. The intraoperative estimated blood loss and the total blood loss were 33% and 41% lower in the TA group than the placebo group, respectively. The blood transfusion rate did not vary significantly (P = 0.191). Except a patient with a dural tear in the placebo group, no other complications were observed. Conclusion: TA significantly reduced the perioperative blood loss in patients undergoing posterior lumbar surgery for stenosis or spondylolisthesis.
The Nas Parallel Benchmarks

A new set of benchmarks has been developed for the performance evaluation of highly parallel supercom puters. These consist of five "parallel kernel" bench marks and three "simulated application" benchmarks. Together they mimic the computation and data move ment characteristics of large-scale computational fluid dynamics applications. The principal distinguishing feature of these benchmarks is their "pencil and paper" specification—all details of these benchmarks are specified only algorithmically. In this way many of the difficulties associated with conventional bench- marking approaches on highly parallel systems are avoided.