Miracle-dz/UniFAR-FTUs huggingface dataset:
THE DYNAMICS OF NEUROHUMORAL MEDIATORS OF VASOCONSTRICTION AND VASODILATION AND TROPONIN I IN PATIENTS WITH ACUTE MYOCARDIAL INFARCTION DEPENDING ON THE DEGREE OF CONCOMITANT OBESITY.

OBJECTIVE The aim: Is to evaluate copetin's, MRproADM's and troponin's I dynamic in patients with acute myocardial infarction depending on the degree of concomitant obesity. PATIENTS AND METHODS Material and methods: The study included 105 patients with AMI. There were formed 2 groups: 1st group of patients with AMI and concomitant obesity (n=75), 2nd group - patients with AMI without obesity (n=30). 37 patients had obesity of the I degree, 38 patients - II degree. The groups were comparable in age and gender. Copeptin, MRproADM, troponin I were determined by enzyme immunoassay method. Data are presented as mean values and the error of the mean (M±m). Differences were considered statistically significant at p<0,05. RESULTS Results: It was found an increased copeptin's level by 73,8 % (p<0,001) in obesity I degree and by 205,9 % in obesity II degree compared with group with isolated AMI, MRproADM - by 30,68 % (p<0,001) and 54,5 % (p<0,001) respectively. Concentration of copeptin was higher by 76 % (p<0,001) in patients with AMI and II degree obesity comparing to patients with obesity of I degree, and MRproADM - by 18,3% (p<0,001) respectively. Troponin I value fully corresponded the comparison group both in obesity of I degree and II degree (p>0,05). CONCLUSION Conclusions: The present study provides evidence that a high activity of copeptin and MRproADM in patients with AMI and obesity of I degree with an excessive activity of a marker of vasoconstriction copeptin in conditions of moderate inadequate to the needs MRproADM functioning in patients with obesity of II degree.
Exploring the Relationships between Possible Selves and Early Teacher Identity of Turkish Pre-service Teachers

Pre-service teacher (PST) education at higher education institutions is pivotal to early teacher identity development. Possible selves theory presents a framework for understanding teacher professional identity, which is theoretically supported but not empirically tested sufficiently. This study set out to examine PSTs’ early teacher identity in the Turkish context and the expected and feared possible selves of PSTs as predictors of early teacher identity through structural equation modeling based on empirical data from 350 freshmen and senior PSTs. The results suggest that PSTs’ expected teacher possible selves have a medium level significant and positive effect on early teacher identity, while feared teacher possible selves have a low level significant and negative effect on early teacher identity. PSTs’ early teacher identity and possible selves were found as very high, which is also examined in terms of gender, grade, and department variables. The results are discussed, and suggestions are offered for pre-service teacher education.
Acidified Diet Increases the Trace Mineral Content in Whole Body Fish Labeo rohita Fingerlings

| The present study was designed to check minerals in fish body with organic acid supplemented diets in Labeo rohita fingerlings. Five experimental diets were prepared containing organic acid (0%), malic acid (2%), citric acid (2%), formic acid (2%), lactic acid (2%) and designed as “OA1, OA2, OA3, OA4 and OA5”, respectively. Eight weeks experimental trail were performed. Water quality characteristics (dissolved oxygen, pH and temperature) were checked daily throughout the trail. Results concluded that the body mineralization in L. rohita was increased by supplementation of organic acid. The maximum body mineralization was noted in fish fed with the dietary group OA3 that contain citric acid and minimum mineralization was noted in the diet OA5 containing lactic acid when compared with other dietary treatments. In conclusion, citric acid showed best response as compared to other dietary supplemented organic groups. Article History Received: April 04, 2018 Revised: June 13, 2018 Accepted: June 20, 2018 Published: August 04, 2018 Authors’ Contributions LS executed the research. MA supervised the study. SZHS did statistical analysis. MF helped in compiling the data. HN and QS helped in writing the article.
Clinical Features in Patients with Acute Pulmonary Edema with Confirmed Coronavirus Disease 2019 (COVID-19): Comparison with Those without Acute Pulmonary Edema

Background: Although poor clinical outcomes have been reported for Coronavirus Disease 2019 (COVID-19), comprehensive data regarding Acute Pulmonary Edema (APE) concomitant with patients with COVID-19 are scarce. This study investigated the clinical features and outcomes of APE in patients with COVID-19. Methods: Of 50 patients enrolled from a COVID-19 registry database, 5 patients presented with APE (APE group) and 45 did not (Non-APE [NAPE] group). Results: Most clinical presentations and in-hospital courses were different between the groups. The APE group was older (P=0.001) and had higher prevalence of underlying diabetes (P=0.005), hypertension (P=0.005), coronary artery disease (P=0.001), stroke/transient ischemic attack (P=0.001) and chronic renal failure (P=0.002). The APE group had significantly higher prevalence of sputum (P=0.002), higher body temperature (P=0.004) and shock (P=0.002). The APE group had significantly higher prevalence of ST depression (P=0.023) and T-wave inversion (P=0.045). The APE group had significantly higher levels of high sensitivity-C Reactive Protein (hs-CRP) (P=0.007), Erythrocyte Sedimentation Rate (ESR) (P=0.001) and procalciton in (P=0.001). The APE group had significantly higher prevalence of bilateral involvement (P=0.002) and multi-lobal involvement (P=0.001) of Ground Glass Opacities (GGO). The APE group required more frequent use of inotropics (P=0.002), ventilator (P=0.001), Angiotensin-converting enzyme inhibitors (P=0.001), diuretics (P=0.001), and antibiotics (P=0.001). The APE group had significantly higher in-hospital mortality (P=0.002). Conclusion: Our study demonstrated that the APE group had higher in-hospital mortality than the NAPE group. A meticulous diagnostic and therapeutic approach should be considered for elderly patients with COVID-19 having diabetes, hypertension, coronary artery disease, chronic renal failure, stroke, and ST depression and T-wave inversion, bilateral, multi-lobal involvement of GGO and high levels of ESR, hs-CRP and procalcitonin at the time of admission.
Comparison of pharmacomechanical and surgical interventions for thrombosed native arteriovenous fistulas

Background This study aims to compare success and patency rates of pharmacomechanical thrombectomy versus open surgical thrombectomy for thrombosed native arteriovenous fistulas. Methods A total of 96 patients (56 males, 40 females; mean age 61±11.7 years; range, 26 to 82 years) with a thrombosed native arteriovenous fistula between January 2016 and December 2018 were retrospectively analyzed. The patients were divided into two groups as pharmacomechanical thrombectomy (n=42) and open surgical thrombectomy (n=54). Primary failure rate and primary patency rate at 6 and 12 months were recorded. Results Of 42 patients in the pharmacomechanical thrombectomy group, 41 (98%) had additional interventions, and primary failure occurred in four patients (10%). Primary failure was seen in 15 (28%) patients in the surgical group. The primary patency rates at 6 and 12 months were significantly higher in the pharmacomechanical treatment group than the surgical group (85% vs. 67% and 78% vs. 55%, respectively; p<0.05). Conclusion Pharmacomechanical thrombectomy procedure yields higher primary patency rates than open surgical thrombectomy for thrombosed native arteriovenous fistula.
Bulgarian species of genus Astragalus as potential sources of mauritianin

Mauritianin is a relatively rare flavonoid, but several studies revealed its pharmacological potential. In this study overground parts of ten Astragalus species were investigated for mauritianin content to find a reliable source of the compound. The quantity of the flavonoid in each extract was determined by a novel high performance liquid chromatography-high resolution mass spectrometry method. For the first time mauritianin is reported in A. cicer, A. onobrychis, A. glycyphyllos, A. glycyphylloides, A. corniculatus and A. ponticus. Only in A. depressus the compound was not found. Significant differences in mauritianin content (from 4 to 1642 ng/mg dry weight) of the samples were observed. Noteworthy, A. onobrychis var. chlorocarpus and A. cicer could be considered as a potential source of the compound, substituting the rare A. monspessulanus subsp. monspessulanus.
Weakly Supervised Deep Learning Methods for Biomicroscopy

Optical microscopy, an invaluable tool in biology and medicine to observe and quantify cellular function, organ development, or disease mechanisms, requires constant trade-offs between spatial, temporal, and spectral resolution, invasiveness, acquisition time, and postprocessing effort. Deep learning technologies have enabled multiple applications that are transforming our day-to-day routines, including the way we approach microscopy. Yet despite the ever-increasing computational power, it is often the lack of labeled training data that is the limiting factor for wide adoption in this domain. Annotating data is often a lengthy and expensive task, since it involves tedious work, generally by skilled experts. In this thesis, I explored “weakly supervised” learning methods targeted at a variety of applications to enhance microscopy images and extract physical information from a single image. The specificity of these “weakly supervised” methods is the fact that they use very little prior information about the image in order to keep the effort to annotate training data as low as possible. Specifically, I reduced the dimensionality of the learning problem by targeting the experiment towards estimating the parameters of a spatially-variant Point Spread Function (PSF) model using a Convolutional Neural Network (CNN), which does not require instrumentor object-specific calibration. Using such a model permitted to simulate realistically accurate training data that could be generalized, once the model was trained, to real microscopy images. I extensively benchmarked different network architectures, training datasets and simulation modalities towards the optimal PSF prediction performance and robustness to image degradation. Starting from the estimated PSF model parameters, I developed a variety of applications, such as a semi-blind spatially-variant deconvolution method for image deblurring and enhancement, a robust and fast microscopy auto-focus, a method for the estimation of the object surface from a single 2D image, and a method for the estimation of the object velocity in a fluid, all of them with minimal need for a priori knowledge about the optical setup.
Noisy Multipath Parallel Hybrid Model for Remaining Useful Life Estimation (NMPM)

The parallel hybrid models of different deep neural networks architectures are the most promising approaches for remaining useful life (RUL) estimation. In light of that, this paper introduces for the first time in the literature a new parallel hybrid deep neural network (DNN) solution for RUL estimation, named as the Noisy Multipath Parallel Hybrid Model for Remaining Useful Life Estimation (NMPM). The proposed framework comprises of three parallel paths, the first one utilizes a noisy Bidirectional Long-short term memory (BLSTM) that used for extracting temporal features and learning the dependencies of sequence data in two directions, forward and backward, which can benefit completely from the input data. While the second parallel path employs noisy multilayer perceptron (MLP) that consists of three layers to extract different class of features. The third parallel path utilizes noisy convolutional neural networks (CNN) to extract another class of features. The concatenated output of the previous parallel paths is then fed into a noisy fusion center (NFC) to predict the RLU. The NMPM has been trained based on a noisy training to enhance the generalization behavior, as well as strengthen the model accuracy and robustness. The NMPM framework is tested and evaluated by using CMAPSS dataset provided by NASA.
Study of the initial glycerol concentration effects upon bacterial cells adaptation and biodegradation kinetics on a submerged aerated fixed bed reactor using biocell® packing

The present work provides an experimental study of the effect of the glycerol concentration on removal performances in a Submerged Aerobic Fixed-Film (SAF) Reactor performing in batch mode. This study consisted in adding various initial substrate concentrations of synthetic solutions (glycerol) in order to assess their effects on biodegradation kinetics and then on bacterial cells adaptation. For this purpose, three series of tests were made. The first two series were carried out with initial Chemical Oxygen Demand concentrations respectively of 330 mgO2/L (SL) and 1120 mgO2/L (SH). The third series (SS) was carried out with gradually increasing concentrations, in which initial COD values were 480, 590 and 760 mgO2/L. It has been found that the adaptation time decreased when the initial concentration increased. But, when synthetic solutions were renewed for a new adaptation, better performances were observed. Increasing initial COD solutions (SS test) showed excellent performances; in fact, it seems combine both, the advantage of low substrate concentration (better adaptability, interesting time for adaptation – case of SL test) and of a high concentrated synthetic solutions (better treatment performance and high biodegradation kinetics constant – case of SH test). Received 16 Feb 2016, Revised 17 Apr 2016, Accepted 25 Apr 2016
Adjuvant radiochemotherapy in locally advanced gastric cancer: from evidence to daily clinical practice in a single institution

Background Gastric cancer is one of the main important causes of cancer death in Chile. Objective To report the results of adjuvant radiochemotherapy in advanced gastric cancer. Material and Methods Between 2000 and 2018, 214 subjects aged 23–85 (median, 62) years with lymph node and/or serosa involvement were treated with adjuvant chemoradiotherapy after curative resection. Results With a median follow-up of 41 months, overall 3- and 5-year survival was 54.9% and 40.85%, respectively. On multivariate analysis, the factors associated with lower survival were aged >65 years, stage group and number of lymph nodes involved. Conclusion In patients with locoregionally advanced gastric cancer treated with curative intent with surgery and adjuvant radiochemotherapy, the overall 5-year survival reported from local clinical practice is similar to that reported in randomised series and supports its use as an effective treatment for this type of patients in our country.
HYDROLOGIC AND WATER QUALITY COMPARISON OF FOUR TYPES OF PERMEABLE PAVEMENT AND STANDARD ASPHALT IN EASTERN NORTH CAROLINA

quality differences among pavement types. The four permeable sections were pervious concrete (PC), two types of permeable interlocking concrete pavement (PICP) with small-sized aggregate in the joints and having 12.9% (PICP1) and 8.5% (PICP2) open surface area, and concrete grid pavers (CGP) filled with sand. The site was located in poorly drained soils, and all permeable sections were underlain by a crushed stone base with a perforated pipe underdrain. The effects of rainfall depth, rainfall intensity, antecedent dry period, season, and lot age were evaluated for all pavement types. Hydrologic differences among pavements were evaluated for surface runoff volume, total outflow volume, peak flow rate, and peak delays. All permeable pavements significantly and substantially reduced surface runoff volumes and peak flow rates when compared to standard asphalt (p<0.01), but of the permeable pavements, CGP generated the greatest surface runoff volumes (p<0.01). The PICP1 and CGP generated significantly lower outflow volumes than asphalt and the other permeable pavement sections evaluated (p<0.01). These two sections were able to store up to 6mm of rainfall, a volume equivalent to roughly 30% of the median rainfall event that occurred during the study. Further, these sections had the lowest peak flows and the longest peak delays. The response of the PICP1 cell was likely due to an increased base storage volume resulting from an elevated pipe underdrain; whereas, the CGP cell response was attributed to water retention in the sand fill layer. Permeable pavement surface runoff and peak flow delay appeared to be most dependent on rainfall intensity, whereas outflow volume and peak flow reductions were most dependent on rainfall depth. Rainfall and asphalt runoff water quality samples were compared to permeable pavement subsurface drainage samples for pH and concentrations of total nitrogen (TN), nitrite-nitrate as nitrogen (NO 2,3-N), total Kjeldahl nitrogen (TKN), ammonia as nitrogen (NH 4-N), organic nitrogen (ON), total phosphorus (TP), orthophosphate (OPO 4), and total suspended solids (TSS). Due to problems with initial laboratory results, analyses of water quality parameters pavements were effective in buffering acidic rainfall pH (p<0.01). The pH of permeable pavement subsurface drainage was higher than that of asphalt runoff (p<0.01) and the PC cell had the highest pH values of all pavement sections (p<0.01). Further, permeable pavement subsurface drainage tended to have lower NH 4-N and TKN concentrations than asphalt runoff and rain. With the exception of the CGP cell, permeable pavements had higher NO 2,3-N concentrations …
Do different sampling designs produce differences in the metrics of curimba, Prochilodus lineatus (Characiformes: Prochilodontidae)?

Successful fisheries studies require an appropriate sampling design that produces unbiased data, because biased data do not allow valid conclusions to be made about the statistical population (Zar, 2010). Given that it is rarely possible to obtain data from all the sample units of a statistical population (Pagano, Gauvreau, 2000; Hansen et al., 2007), a sampling design must be probabilistic so that each sample unit has the same chance of being sampled (Pagano, Gauvreau, 2000). A sampling design stipulates how samples are organized in space and/or time in an observational study (Gotelli, Elisson, 2004), also called a mensurative experiment (Hurlbert, 1984), which is when the researcher generally does not control any of the variables being quantified. The general sampling designs most frequently used are simple random, systematic, stratified and clustered, which are all probabilistic (Wilde, Fisher, 1996; Pagano, Gauvreau, 2000; Hansen et al., 2007; Noble et al., 2007). However, among these general sampling designs it is still possible to establish more specific sampling designs since there is more than one option for determining the location of fish sampling sites. Specific sampling designs may be fixed – i.e., the same sampling sites are sampled successively in time, or variable – i.e., new Do different sampling designs produce differences in the metrics of curimba, Prochilodus lineatus (Characiformes: Prochilodontidae)?
§«“¡ —¡æ—π∏å¢Õß§«“¡‡¢â¡¢—π ́’√—¡√’ ‘ μ‘π°—∫¥—TMπ’¡«≈°“¬¢Õß‡¥Á°«—¬√ÿàπÕâ«π „π®—ßÀ«—¥¡À“ “√§“¡ The Relationship of Serum Resistin Concentration and Body Mass Index (BMI) of Obese Adolescent in Mahasarakam Province

Resistin is a newly discovered peptide hormone with impact on insulin sensitivity was proposed as a new mechanism to explain the pathogenic sequence of adipocyte-obesity-insulin resistance. This research aimed to determine serum resistin concentration levels in adolescents and the relationship between resistin concentration and body mass index (BMI), in selected high school students in Mahasarakam province. The research protocol and 77 consented students who enrolled in this study were ethical approved by Mahasarakam research ethic committee division. The students weight, height, BMI, fasting blood sugar (FBS) and triglyceride (TG) were examined during March to June 2008. This study found that: 16 male and 61 female adolescent students with average weight 71.27±13.87 kg, height 1.6±0.07 m, BMI 27.67±4.24 kg/m, biceps skinfold thickness 15.27±6.89 mm, triceps skinfold thickness 23.55±7.54 mm, TG 77.13±43.92 mg/dL, FBS 87.74±8.21 mg/dL and resistin 5.69±0.93 mg/dL. The weight and height of male is higher than female (p =0.003, p<0.001 respectively), but biceps skinfold thickness, triceps skinfold thickness, TG of female is higher than male. Resistin was detected in female; concentrations ranged from 3.83 mg/dL to 7.82 mg/dL and in male 3.91 mg/dL to 6.52 mg/dL. In female resistin levels were higher (5.87±0.84) than male (4.98±0.94) (p<0.001). The relationship analysis found that: resistin serum levels in both male and female related to BMI, biceps skinfold thickness, triceps skinfold thickness statistical significantly. The furthermore it should be the parameter used as association of serum resistin with markers of obesity (eg. weight, BMI, FBS) was strongly statistical significantly (p<0.05) in both gender groups, this may be determinant to indicated insulin resistance prior fasting blood sugar was elevated, but vise-versa for FBS in male. Keyword: resistin, body mass index (BMI) and adolescent J Sci Technol MSU 2008;27(4):362-368
Effects of joint manipulation in the upper cervical spine on the signs and symptoms of subjects with headache: a blind, clinical trial

BACKGROUND Headaches are among the most common diseases and, according to the World Health Organization, a large part of the population has been or will be affected by this symptom. However, the minority of people with headache disorders worldwide are adequately diagnosed by a health care provider and, therefore, headaches have been underestimated, under-recognized and undertreated throughout the world. Headache can be defined as any pain that is felt in the head segment and can be classified as primary (when pain is not a symptom of another pathology) or secondary to another disease. Among primary conditions, migraine and tension-type headache are the most common and disabling. The latter is the most common form of headache, both in adults and adolescents. In addition, tension-type headache can cause substantial levels of disability for patients and their families as well as for society as a whole due to the high prevalence in the general population. Regarding pain, studies have shown that the cervical spine shows hyperalgesia responses in children with headache, and they also suffer from neck pain and that this is a negative prognostic factor for headache. Thus, some authors suggest an evaluation of the cervical spine when the subject has headache. The diagnostic criteria formulated by the international cervicogenic headache study group include: unilateral headache without changing sides; pain occurring with movement of the neck; pain during head support in an unconventional position and / or external pressure on the upper cervical or occipital region; restriction of cervical mobility; ipsilateral neck, shoulder and arm pain. In fact, cervical disorders have traditionally been linked to different types of headaches. For example, reduced neck mobility has been found in subjects suffering from cervicogenic headache and chronic tension-type headache (CTTH), but not in subjects with migraine. Thus, it is important that the evaluation and intervention in the cervical spine are part of the approach of the patient with cervicogenic headache. Mayoralas et al. assessed the cervical mobility of children with and without headache and found that those who had headache showed less cervical mobility for flexion, extension and right and left inclinations, but not for rotation, when compared to children without headache. Fernandez de las Penãs et al. found decreased cervical mobility in adults with CTTH. The treatment of this type of headache is challenging.