Miracle-dz/UniFAR-FTUs huggingface dataset:
Supporting People with Acquired Brain Injury to Use a Reminding App; Narrow-deep vs. Broad-shallow User Interfaces

People with memory impairments following an acquired brain injury stand to benefit from smartphone apps as memory aids. Due, in part, to usability issues they use smartphone-based reminding less than the general population. Evidence suggests this group may benefit from user interface (UI) designs with more screens with less information per screen (narrow-deep UI) rather than fewer screens with more information per screen (broad-shallow UI). This study compared the difference in speed, accuracy, guidance needed, and task load for 32 people with acquired brain injury when setting reminders using narrow-deep and broad-shallow UI. They were also given cognitive assessments (measuring selective attention, executive functioning, and overall executive and memory ability) and interviewed about their UI preference. There was a significant difference in accuracy; participants were less accurate (they made two more errors on average for every three reminders set) using a broad-shallow compared to narrow-deep UI. The reason for this difference was that participants omitted more information when using broad-shallow UI. There were no differences in speed, guidance required, and overall task-load. Participants with better selective attention and more experience with smartphones benefited the most from narrow-deep UI compared to broad-shallow UI. Most participants preferred one UI over the other. Those who preferred narrow-deep found it easier to use, that they missed less information and liked having one piece of information at a time. Those who preferred broad-shallow found it easier to review the information and felt less likely to lose track. The findings can inform that implementation of UI choices to make apps more accessible for those with cognitive impairments.
Diverse Chromobox Family Members: Potential Prognostic Biomarkers and Therapeutic Targets in Head and Neck Squamous Cell Carcinoma

Background The Chromobox (CBX) family members were involved in a variety of physiological and oncological processes through the regulation of the epigenetic modification of chromatin. However, the comprehensive analysis of the CBX family in head and neck squamous cell carcinoma (HNSC) is lacking. Methods In this work, we used multiple online databases and tools to investigate the roles of CBX family in aspects of gene expression, prognostic evaluation, genetic alteration, immune micro-environment of tumor, and status of methylation. Results The mRNA expression levels of CBX1, CBX3, and CBX5 were aberrantly increased in patients with HNSC, while CBX7 was aberrantly decreased. Higher expression of CBX7 was significantly associated with longer OS. Within the 5–11% of genetic alteration rate of CBXs, CBX3 ranked the highest and CBX5/7 ranked the lowest. SPRR1B, S100A7, CASP14, CDSN, LCE3D were the top 5 neighbor genes with the strongest association with CBXs in HNSC patients. Signaling pathways such as epidermal cell differentiation, cornification, and peptide cross-linking were demonstrated to have a strong association with CBX genes. The profiles of immune cell infiltration had high similarity for the group of HNSC patients stratified by expression of CBXs. The methylation levels of CBX1 and CBX5 significantly decreased, while that of CBX7 significantly increased in HNSC samples when compared with normal tissue. Conclusion In conclusion, the CBX family showed its valuation for further investigation in HNSC. Our research highlighted that CBX7 had the potential to be a novel diagnostic and prognostic biomarker for patients with HNSC.
Neutralizing Antibodies and Cellular Immune Responses Against SARS-CoV-2 Sustained One and a Half Years After Natural Infection

Background COVID-19 has caused more than 2.6 billion infections and several million deaths since its outbreak 2 years ago. We know very little about the long-term cellular immune responses and the kinetics of neutralizing antibodies (NAbs) to SARS-CoV-2 because it has emerged only recently in the human population. Methods We collected blood samples from individuals who were from the first wave of the COVID-19 epidemic in Wuhan between December 30, 2019, and February 24, 2020. We analyzed NAbs to SARS-CoV-2 using pseudoviruses and IgG antibodies to SARS-CoV-2 spike (S) and nucleocapsid (N) protein using enzyme-linked immunosorbent assay in patients’ sera and determined SARS-CoV-2-specific T-cell responses of patients with ELISpot assays. Results We found that 91.9% (57/62) and 88.9% (40/45) of COVID-19 patients had NAbs against SARS-CoV-2 in a year (10–11 months) and one and a half years (17–18 months), respectively, after the onset of illness, indicating that NAbs against SARS-CoV-2 waned slowly and possibly persisted over a long period time. Over 80% of patients had IgG antibodies to SARS-CoV-2 S and N protein one and a half years after illness onset. Most patients also had robust memory T-cell responses against SARS-CoV-2 one and a half years after the illness. Among the patients, 95.6% (43/45) had an IFN-γ-secreting T-cell response and 93.8% (15/16) had an IL-2-secreting T-cell response. The T-cell responses to SARS-CoV-2 were positively correlated with antibodies (including neutralizing antibodies and IgG antibodies to S and N protein) in COVID-19 patients. Eighty percent (4/5) of neutralizing antibody-negative patients also had SARS-CoV-2-specific T-cell response. After long-term infection, protective immunity was independent of disease severity, sex, and age. Conclusions We concluded that SARS-CoV-2 infection elicited a robust and persistent neutralizing antibody and memory T-cell response in COVID-19 patients, indicating that these sustained immune responses, among most SARS-CoV-2-infected people, may play a crucial role in protection against reinfection.
MOLECULAR CHARACTERIZATION AND MATING STUDY OF Fusarium proliferatum FROM VARIOUS HOSTS IN MALAYSIA

Fusarium proliferatum is a well-known plant pathogenic fungus-infected many crops. The present study was carried out to molecularly identified and characterized morphologically identified F. proliferatum from various hosts and substrates. The species identity of the isolates was verified as F. proliferatum based on TEF-1α sequences and phylogenetic analysis indicated high intraspecific variations. RFLP-IGS analysis also indicated high intraspecific variations of which the isolates were clustered into three RFLP Groups (I, II, and III) comprising 67 IGS haplotypes. Seventy isolates were crossed-fertile and proven to be members of mating population D (MP-D) of Gibberella fujikuroi while four isolates were infertile. A high level of intraspecific variations is vital for F. proliferatum adaptation and survival in the host and environment. Correct species identification of F. proliferatum is important as the fungus is a well-known plant pathogen and mycotoxin producer. Correct species identity is also essential to strategize suitable disease control methods as well as to predict their host range and mycotoxin production.
Epidemiology of Hypothyroidism, Hyperthyroidism and Positive Thyroid Antibodies in the Croatian Population

Simple Summary The aim of this paper was to analyse the prevalence of hypothyroidism and hyperthyroidism in the Croatian population. This is the first epidemiological study of its kind conducted in our population. It is important to correctly diagnose thyroid dysfunction due to the detrimental effects of thyroid dysfunction on human health (especially in pregnant women and patients with cardiovascular diseases). The results of our study conducted on 4402 individuals, showed a higher prevalence of hypothyroidism in our country (10.5%) compared to other countries, while the prevalence of hyperthyroidism was quite similar (1.3%). We also observed that a high proportion of thyroid disorders remained undiagnosed (as many as 92.6% subclinical hypothyroid, 93.9% clinical hypothyroid, 83% subclinical hyperthyroid and 71.4% clinical hyperthyroid participants). Therefore, our study indicates that investing in prevention programs is crucial. Abstract Thyroid dysfunction appears to be the leading endocrine disorder. We conducted a cross-sectional study on 4402 individuals from three Croatian cohorts. The aim of this study was to analyse the prevalence of diagnosed and undiagnosed hypothyroidism, hyperthyroidism (subclinical and clinical) and positive thyroid antibodies in the Croatian population. The results of the study indicated that 17.6% of participants were euthyroid with positive antibodies. The prevalence of clinical and subclinical hypothyroidism was 3% and 7.4%, respectively, while the prevalence of clinical and subclinical hyperthyroidism was 0.2% and 1.1%, respectively. Among them, 92.6% subclinical hypothyroid, 93.9% clinical hypothyroid, 83% subclinical hyperthyroid and 71.4% clinical hyperthyroid participants were undiagnosed. Finally, the prevalence of undiagnosed subclinical and clinical hypothyroidism in our population was 6.9% and 2.8%, respectively, while the prevalence of undiagnosed subclinical and clinical hyperthyroidism was 0.9% and 0.1%, respectively. Women showed a higher prevalence of thyroid disorders; 1.57 times higher odds of euthyroidism with positive antibodies, 2.1 times higher odds of subclinical hyperthyroidism, 2.37 times higher odds of clinical hypothyroidism and 1.58 times higher odds of subclinical hypothyroidism than men. These results indicate an extremely high proportion of undiagnosed cases, and therefore require investments in a prevention programme.
The Effect of Teaching a Sports and Health Course on the Attitudes of the Hashemite University Students towards Certain Healthy Food Habits and Physical Activities Practice

This study aimed at identifying the effect of teaching a sports and health course on the Hashemite University students' attitudes towards certain food habits and the practice of physical activities. The study sample consisted of (100) male and female students, who are enrolled in the sports and health course in the first semester of the academic year 2020/2021. The instrument of Saleh and Al-Ahmadi (2016) was used for our study, which included (40) items distributed over two domains (healthy eating habits and physical activities practice). The scientific coefficients of the study instrument were calculated, and the total reliability coefficient amounted (0.91), as well as the means (M's) and standard deviations (SD's). Furthermore, the Test-Retest and MANOVA procedures were applied to identify the differences among the means and to answer the study questions. The results showed statistically significant differences between the pretest and posttest scores, which were in favor of the posttest. In addition, there were differences in the means of all the domains and the instrument, as a whole, between the pretest and posttest, which are ascribed to the gender variable, in favor of the females in the healthy eating habits domain, and in favor of males in the physical activities practice. The results further showed differences among the means in all the domains and the instrument, as a whole, between the pretest and posttest attributed to the college variable, in favor of the humane science colleges. Moreover, there were differences among the means in all the domains and the instrument, as a whole, between the pretest and posttest ascribed to the academic year variable, which were in favor of the first year in the physical activities practice domain. In the light of these results, the researcher concluded that teaching a "sports and health" course, with its concepts and information, has a positive effect in changing the students' attitudes towards the healthy eating habits and physical activities practice. The researcher recommended that this course should be introduced as a compulsory course for all the university students. Received: 31 October 2021 / Accepted: 10 December 2021 / Published: 5 March 2022
Gene Expression Analysis of Potato (Solanum tuberosum L.) Lipoxygenase Cascade and Oxylipin Signature under Abiotic Stress

The metabolism of polyunsaturated fatty acids through the lipoxygenase-catalyzed step and subsequent reactions is referred to as the lipoxygenase (LOX) pathway. The components of this system, such as jasmonates, are involved in growth, development and defense reactions of plants. In this report, we focus on dynamics of expression of different LOX pathway genes and activities of target enzymes with three abiotic stress factors: darkness, salinity and herbicide toxicity. To obtain a more complete picture, the expression profiles of marker genes for salicylic acid, abscisic acid, ethylene, auxin and gibberellin-dependent signaling systems under the same stresses were also analyzed. The gene expression in Solanum tuberosum plants was analyzed using qRT-PCR, and we found that the LOX-cascade-related genes responded to darkness, salinity and herbicide toxicity in different ways. We detected activation of a number of 9-LOX pathway genes; however, in contrast to studies associated with biotic stress (infection), the 9-divinyl ether synthase branch of the LOX cascade was inhibited under all three stresses. GC-MS analysis of the oxylipin profiles also showed the main activity of the 9-LOX-cascade-related enzymes after treatment with herbicide and darkness.
The effects of live streaming attributes on consumer trust and shopping intentions for fashion clothing

Abstract Small individual sellers and retailers use live streaming as a direct selling channel to demonstrate and sell their products. This study proposes a framework that examines the influence of live streaming attributes on customer trust and intentions to watch and purchase fashion clothing. Drawing on prior literature, we examine an extensive list of 20 live streaming attributes including product attributes, seller attributes, and other related attributes. The study is performed on 476 Thai consumers with diverse demographics. Results show that product quality and price transparency significantly influence customer trust and intentions to watch and purchase, while seller’s image of being trustworthy and the quality of seller’s Facebook page only show weak relationships. Another finding is that seller pre-announcing their broadcast timing will encourage higher intention to watch. And as expected, the trust in seller positively influences trust in product. These findings suggest opportunities for sellers to focus their attention on important live streaming attributes to develop trust with their customers and increase their customer intentions to watch and purchase. The study concludes with discussion on managerial implications and future work on live streaming commerce for fashion clothing products.
EXPLORING SERVICE LEARNING FROM THE PERSPECTIVE OF EARLY CHILDHOOD PRE-SERVICE TEACHER EDUCATION

Service learning has been stressed as an effective pedagogical approach to enhance students’ professional skills and citizenship for future development. However, service-learning research concerning early childhood pre-service teacher education has been rarely done. This study explored how undergraduate students in an early childhood pre-service teacher education program experienced in seven different service learning activities and discussed the meanings of their experiences from the perspective of early childhood pre-service teacher education. Participants in the study were 99 undergraduate students of early childcare and education. Their speech reflections, SL (Service learning) reports and verbal presentations during the course and service learning were analyzed qualitatively. The study revealed participants experienced emotion processes. In addition, participants learned professional skills and formed their teacher traits. How to balance the student choice and the goals of the course from SL activity needs to be taken into account
MDCT Findings in Gastrointestinal Perforations and the Predictive Value according to the Site of Perforation

Background: Gastrointestinal perforations are a frequent cause of acute abdominal symptomatology for patients in the emergency department. The aim of this study was to investigate the findings of multidetector-row computed tomography of gastrointestinal perforations and analyze the impact of any imaging signs on the presurgical identification of the perforation site. Methods: We retrospectively reviewed emergency MDCT findings of 93 patients submitted to surgery for gastrointestinal perforation at two different institutions. Two radiologists separately reviewed the emergency MDCT examinations performed on each patient, before and after knowing the surgical diagnosis of the perforation site. A list of findings was considered. Positive predictive values were estimated for each finding with respect to each perforation site, and correspondence analysis (CA) was used to investigate the relationship between the findings and each of the perforation types. Results: We did not find inframesocolic free air in sigmoid colorectal perforations, and in rare cases, only supramesocolic free fluid in gastroduodenal perforations was found. A high PPV of perivisceral fat stranding due to colonic perforation and general distension of upstream loops and collapse of downstream loops were evident in most patients. Conclusions: Our data could offer additional information on the perforation site in the case of doubtful findings to support surgeons, especially in planning a laparoscopic approach.
Phylogeographic analysis of Ligidium japonicum (Isopoda: Ligiidae) and its allied species reveals high biodiversity and genetic differentiation in the Kanto region, Japan

Research of the diversity and evolutionary history of Japanese soil invertebrates is scarce. Molecular data analysis can help to elucidate species classifications and evolutionary processes. We analyzed the mitochondrial cytochrome oxidase subunit I (COI) and nuclear 28S rDNA genes and the morphology of the male pleopod 2 endopod of Ligidium japonicum and its allied species from 67 sites in Hokkaido, Honshu and Shikoku, where only L. japonicum is thought to occur. We found males of the L. japonicum complex with a pleopod 2 endopod morphology matching that of the L. japonicum syntype specimens, except for the number of denticles at the inner margin. There were also more than five species that differed morphologically from the L. japonicum complex, and most of these species had allopatric distributions despite the absence of obvious barriers. A time‐calibrated molecular phylogeny implied that the L. japonicum complex of the Kanto region first differentiated allopatrically in the mountains; this was followed by independent dispersal of three lineages to the Kanto Plain and Boso Peninsula, where secondary contact occurred. Two of the three sympatrically distributed L. japonicum complex lineages had a significant difference in the number of denticles at the inner margin of male pleopod 2 endopods. This variation implies the presence of cryptic species within the L. japonicum complex.
DETERMINANTS AFFECT MOBILE WALLET CONTINUOUS USAGE IN COVID 19 PANDEMIC: EVIDENCE FROM VIETNAM

Abstract Disruptive technology has been prominent as a spotlight with countless innovations that improve human’s life efficiently. In Vietnam, COVID-19ʹs outbreak has reinforced citizens to adopt other types of payment without using cash, which easily diffuses virus. Till now, the number of studies related to continuance usage of mobile wallets in Vietnam has been rare. Hence, our purpose in this research is to study continuance usage in COVID-19 through determinants. This paper concentrates on Millennials and Zillennials living Ho Chi Minh City. PLS-SEM with data collected from questionnaires assesses the conceptual model that indicates the correlation between UTAUT2ʹs constructs, trust, price saving orientation, behavioral intention and continuance usage. As predicted, the findings show that there are positive relationships among all determinants. In the event of effort expectancy and social influence, despite unsatisfactory of statistical significance, they reflect current context. Besides, direct positive influences from two variables to behavioral intention lead to further research studies after the pandemic to conclude properly about their significance. From the study’s result, business strategies together with security’s policies have to be modified by providers as well as the government to motivate mobile wallet adoption in Vietnam, amplifying cashless society and financial inclusion targets.
Comparative assessment of thermal and thermochemical activation methods of South African kaolinite for effective adsorptive sequestration of humic acid from aqueous media

ABSTRACT Current research has demonstrated that the adsorption capacity of raw kaolin is considerably low. Advances in kaolin activation for enhanced utility and improved adsoptibility of pollutants include thermal treatment, acidification, or combined treatment. In this work activation of South African kaolinite with sulfuric acid and calcination is studied. Comparing the FTIR spectra of the activated kaolin i.e thermochemical treated kaolin (HAK) and thermal treated kaolin (HK) with raw kaolin the following main observation were noted; the bands attributable to Si-O stretching vibration (1023 and 1095 cm−1) increased in intensity by 61 and 59% for HK and HAK, respectively. Increasing the humic acid (HA) concentration (0.5–20 mg/L) increased the HA uptake for both adsorbents, HK increased from 0.52 to 0.75 mg/g while HAK increased from 0.59 to 0.86 mg/g. The adsorption of HA was delineated better by a pseudo-second-order model in both cases (Qe = 0.810; 0.793 mg/g for HK and HAK, respectively). From the synchronous spectra, two auto peaks were observed at (1650;1650) and (3246;3246) indicating concurrent and similar HA adsorption behavior on either of the adsorbents. From the results, it can be concluded that activation of kaolin improved its adsoptibility capacity for HA.
Progressivity analysis of pleomorphic adenoma toward carcinoma ex pleomorphic adenoma

Background: Pleomorphic adenoma (PA) is a benign salivary gland tumour with high incidence and recurrence after treatment. It may recur with the same appearance or develop toward malignancy, namely as carcinoma ex pleomorphic adenoma (CXPA). Howthis tumour can transform into a CXPA remains unclear. Purpose: The aim of this study was to analyse the possibility of pathogenesis and progressivity of PA to CXPA. Methods: Twenty-four samples of PA and three control samples of CXPA were stained with haematoxylin and eosin (HE), Mallory’s trichrome, and Periodic acid–Schiff (PAS). All of the PA cases were identified through different kinds of stroma, tumour cells types, morphologic patterns, or else through atypical appearance of the PA similar to the CXPA. Results: Twenty-four samples of PA demonstrated that the most dominant stroma was myxofibrous, and the dominant tumour cell type was plasmacytoid cells with a trabecular pattern. Additionally, in the pleomorphic histological picture of adenomas we found several patterns of malignant tumour behaviour, including pseudopodia, metaplasia and hyalinisation, and cholesterol crystals that are thought to come from fat cell necrosis derived from adipose metaplasia. Conclusions: PA displays several atypical characteristics that have the potential to develop into malignancies such as CXPA, due to capsular infiltration, necrosis, hyalinization and high mitotic activity of cells, but all these atypical characteristics that we observed still cannot be clearly classified as CXPA because they require other specific examinations.