Miracle-dz/UniFAR-FTUs huggingface dataset:
Multi-Institutional Breast Cancer Detection Using a Secure On-Boarding Service for Distributed Analytics

The constant upward movement of data-driven medicine as a valuable option to enhance daily clinical practice has brought new challenges for data analysts to get access to valuable but sensitive data due to privacy considerations. One solution for most of these challenges are Distributed Analytics (DA) infrastructures, which are technologies fostering collaborations between healthcare institutions by establishing a privacy-preserving network for data sharing. However, in order to participate in such a network, a lot of technical and administrative prerequisites have to be made, which could pose bottlenecks and new obstacles for non-technical personnel during their deployment. We have identified three major problems in the current state-of-the-art. Namely, the missing compliance with FAIR data principles, the automation of processes, and the installation. In this work, we present a seamless on-boarding workflow based on a DA reference architecture for data sharing institutions to address these problems. The on-boarding service manages all technical configurations and necessities to reduce the deployment time. Our aim is to use well-established and conventional technologies to gain acceptance through enhanced ease of use. We evaluate our development with six institutions across Germany by conducting a DA study with open-source breast cancer data, which represents the second contribution of this work. We find that our on-boarding solution lowers technical barriers and efficiently deploys all necessary components and is, therefore, indeed an enabler for collaborative data sharing.
Systems theoretic process analysis applied to Air Force acquisition technical requirements development

The Air Force experienced 12 Class A aviation mishaps in 2016, which resulted in 16 fatalities and 9 destroyed aircraft. So far in 2017, The Air Force has again experienced 12 Class A mishaps with 5 fatalities and 7 destroyed aircraft. (1) In addition to these mishaps, development of new aircraft or modifications to aircraft often take well over the planned duration. Developmental test identifies design deficiencies that must be addressed before the aircraft is fielded, which requires expensive and lengthy redesign cycles. A systems approach to design with humans included as part of the system can improve both the development process and aviation safety. Such an approach was created by Professor Nancy Leveson at MIT and is called Systems Theoretic Process Analysis (STPA). STPA is shown to be applicable to the Air Force acquisitions process throughout the product lifecycle. STPA is also compliant with the airworthiness handbook, MIL-HDBK-516C, and STPA documentation is beneficial to the airworthiness certification inspectors. STPA is applied to two use cases. One is a conceptual JSTARS aircraft, and the other is an unmanned aerial vehicle (UAV) that was modified from a general aviation aircraft. The Air Force is currently in source selection for a replacement to the JSTARS aircraft. The high-level STPA analysis is for a functional replacement to the JSTARS aircraft, as would be needed early in the acquisitions process. Additionally, accidents, hazards, and a safety control structure are developed for the JSTARS support system. The UAV analysis is more detailed, and provides information that is necessary during the Technology Maturation & Risk Reduction phase of an acquisition process. Thesis Supervisor: Nancy G. Leveson Title: Profess of Aeronautics and Astronautics and Engineering Systems
Prevalence of Chondral Lesion in Knee Arthroscopy

Introduction: Chondral lesions are painful and disabling, have a poor capacity for repair, and may predispose patients to early osteoarthritis. Chondral lesions are difficult to diagnose clinically because meniscal injuries also have similar features and clinical signs have low predictive value and specificity. Arthroscopy is the definitive modality of diagnosis. The purpose of this study is to provide a data on prevalence of chondral lesions in patients with symptomatic knees requiring arthroscopy. So that probable outcomes in terms of pain and swelling of the knee following arthroscopy can be explained to the patient. Method: This was hospital based prospective observational study. There were 75 patients (45male and 30female) of the age group 18-50 years included in this study. Patients having symptomatic knee pain were screened clinically and those fulfilling inclusion criteria were included in study. Patient profile, clinical and arthroscopic findings were recorded in proforma. Chondral lesions were graded according to Outer bridge classification system. Results: Chondral lesions were found in 49.33% (n=37) of all patients (n=75) with average age of 29 years. Most of the patients were students and average duration of symptoms was 18 months. In these patients, 60% related their current knee problem to a previous trauma. Outer bridge Grade III accounted 46% of all lesions. Of the chondral lesions, 50% were in the medial femoral condyle, 17% in patella, 16% in lateral femoral condyle and 10% in trochlea. Concomitant medial meniscus injury, anterior cruciate ligament injury or both were found in 19%, 13%and 17% of the cases respectively. Conclusion: Our study supports that articular cartilage defects are common findings in knee arthroscopy. So patients with meniscus like symptoms but not diagnostic clinically or radiologically should always have the suspicions of chondral lesion. However the findings could not be generalized because of relatively small sample size.
How to manage online review

Background Due to new technologies, electronic word-of-mouth (eWOM) is becoming increasingly important, and has proven to have a significant impact in the decision-making process within the tourist industry. There is a large assortment of research focusing on why consumers voice their opinion online and engage in eWOM. However, there is little research to be found concerning how hotels currently manage online review sites from a service management perspective. Purpose The purpose of this thesis will focus on how hotels actively incorporate online review sites in their management and marketing strategy from a service management perspective. Method Primaryand secondary sources have been used in order to fulfil the purpose of this thesis. A multiple case study including in-depth interviews as well as observations has provided important empirical findings for the analysis and conclusion. Conclusion Through this thesis, the authors have been able to establish how hotels can work successfully with online review sites from a service management perspective. The strategic issue concerned with eWOM is how to encourage customers to interact through TripAdvisor and write and share reviews. In addition, how to treat the online reviews maturely, and how to interact and use the information is imperative.
A CAUSAL RELATIONSHIP BETWEEN QUALITY MANAGEMENT PRACTICES, SUPPLY-CHAIN PRACTICES, DEMAND-CHAIN PRACTICES, AND COMPANY PERFORMANCE

Studi ini mengembangkan suatu hubungan kausal antara lima konstruk penelitian Quality Management Practices (QMP), Supply-Chain Practices (SCP), Demand-Chain Practices (DCP), Company Performance (Value-Gain Performance atau VGP dan Monetary-Gain Performance atau MGP) dengan menggunakan Structural Equation Modeling (SEM)—studi kasus pada industri migas di Indonesia. Model konseptual penelitian ini merupakan kolaborasi dari berbagai penelitian sebelumnya yang terkait dengan enam dimensi praktik manajemen kualitas berbasis Deming’s 14 points sebagai variabel independen, manajemen rantai pasokan yang terintegrasi (sektor hulu dan sektor hilir migas) sebagai variabel mediator, dan kinerja perusahaan (non keuangan dan keuangan) sebagai variabel dependen. Berdasarkan model struktural akhir menunjukkan paraktik manajemen kualitas (QMP) memiliki pengaruh positif lebih besar ke praktik rantai pasokan (SCP) daripada ke praktik rantai permintaan (DCP). QMP berpengaruh langsung ke kinerja non keuangan perusahaan (VGP) dan tidak berpengaruh langsung ke kinerja keuangan perusahaan (MGP). QMP juga berpengaruh tidak langsung ke MGP melalui SCP, DCP, dan VGP. berpengaruh VGP. hubungan kausal antar konstruk penelitian memberikan gambaran bahwa perusahaan migas di Indonesia mempertimbangkan kinerja keuangan (VGP) untuk meningkatkan kinerja keuangan perusahaan (MGP). contoh ketepatan pasokan dsitribusi merupakan faktor untuk perbaikan secara sistemik. model struktural akhir didukung oleh nilai X 2 /df, GFI, AGFI, CFI, RMR, RMSEA, P, yang secara simultan menunjukkan the best fit to the data. ini memberikan kontribusi bahwa model penelitian ini sangat berpotensi untuk dilakukan studi replikasi untuk industri manufaktur maupun jasa. Penelitian berikutnya perlu membuktikan persamaan dan perbedaan antara industri manufaktur dan jasa melalui model struktual dari industri migas di Indonesia. Bagi pihak manajemen perusahaan migas di Indonesia, penelitian digunakan untuk membuat prioritas perbaikan terpadu.
Characterizing Germanium Junction Transistors

Transistors have provided the basis of modern electronics. Being relatively intricate devices, and often exhibiting intense parameter variation, this type of electronic devices has motivated much research interest especially regarding their characterization and modeling. In this work, we apply a recently reported modeling methodology, based on the Early effect, for characterizing new old stock NPN and PNP small signal germanium junction transistors and comparing them to more modern silicon bipolar junction devices. The Early approach is special in the sense that its two parameters, namely the Early voltage $V_a$ and a proportionality parameter $s$, are fixed and independent of transistor operation. Remarkable results are obtained, including the fact that the four considered groups, namely NPN and PNP germanium and silicon devices, occupy mostly non-overlapping regions in the Early parameter space, with PNP devices presenting larger parameter variability in both cases. Surprisingly, the considered germanium devices exhibited smaller parameter variability than observed for the silicon counterparts. When mapped into the more traditional space defined by the current gain and output resistance parameters, the four transistor groups exhibited much larger overlaps and yielded a clustering structure much less organized than allowed by the Early mapping. This result suggest that the Early representation of transistors is more compatible and inherently related to the structure of amplifying devices such as those considered in this work. In addition, it was verified that the center of mass of each of the NPN-PNP pairs of germanium and silicon devices are crossed by respective $\beta$-isolines for gains of 130 and 250, respectively. Germanium devices were also characterized as having smaller output resistance and smaller magnitudes of Early voltage.
CHEMICAL COMPOSITION OF BOVINE MILK DURING THE FIRST WEEK POSTPARTUM AND ITS INFLUENCE BY SOME HEAT TREATMENTS

Bovine colostrum is the early milk produced by cows during the first several days postpartum. This early milk has a nutrient profile and immunological composition substantially different from mature milk. In the present study the chemical composition and immunoglobulin G (IgG) of bovine milk during the first week of postpartum were determined and the effect of heat treatments on bovine milk IgG contents was evaluated. Individual milk samples were collected from five cows at 0- 0.5, 1, 2, 3, 4, 5, 6 and 7 days postpartum. The obtained results showed that the total solids, total protein, fat and ash contents decreased irregular with time after parturition, while the lactose content increased. The concentrations of IgG were significantly higher during 0-0.5 and 1 st days than those of other days postpartum, where the mean±SD of IgG concentrations were 122.60±5.24 and 118.44±5.90 g/L during 0-0.5 and 1 st days postpartum, respectively. However, IgG concentrations were dropped markedly with time progress of lactation at the end of the first week (7 th day), the mean±SD of IgG concentration was 55.16±17.30 g/L that dropped to 55.01% when compared with its concentrations at 0-0.5 day. IgG of bovine milk was influenced by heat treatments, where the concentrations of IgG in thermal treated milk were decrease to 28.24, 30.27 and 30.18% at 63°C/30 min and 57.33, 73.54 and 95.1% at 72°C/15 sec during 1, 2 and 3 days postpartum, respectively. On the other hand, the most thermal influence on IgG in milk was during thermal heated at 100°C/10 min, where the percentages of losses were 95.72% at 1 st and 100% at 2 and 3 days postpartum.
Paraoxonase Polymorphism (Gln 192 -Arg) Is Associated with Coronary Heart Disease in Japanese Noninsulin-Dependent Diabetes Mellitus

Serum paraoxonase/arylesterase (PONA) is associated with high-densitylipoproteinandmaypreventoxidationoflow-densitylipoproteinbyhydrolyzinglipidperoxides.Arecentreportsuggestedanassociationofglutamine(Atype)/arginine(Btype)polymorphismatposition192ofPONAgenewithcoronaryheartdisease(CHD)amongCaucasianpa-tientswithnoninsulin-dependentdiabetesmellitus(NIDDM). However,conflictingresultshavealsobeenreported.Toinvestigatethesignifi-canceofthispolymorphisminthepathogenesisofCHD,weperformedanassociationstudyofthispolymorphismwithCHDinJapaneseNIDDMpatients.Wegenotyped164patientswithNIDDM,42withCHD,and122withoutCHD.OtherknownriskfactorsforCHDwere matched between the 2 groups. AB (cid:49) BB isoforms were detected in 41 of 42 diabetic patients with CHD. The proportion of B allele carriers (AB (cid:49) BB) was significantly higher than that of AA carriers among di- abetic patients with CHD compared with those without CHD ( (cid:120) 2 (cid:53) 7.68, P (cid:53) 0.003). Multivariatelogisticregressionanalysesshowedamarkedly examinetriglyceridelevelsbetweentwogroups;Kruskal-Wallistestwasusedforacomparisonoftriglyceridesamongthreegroups;andStu-dent’s t -test was used for analysis of other parameters. Chi-squared test and Fisher’s exact test were performed to compare the distribution of PONA genotypes and allele frequencies, respectively. Student’s t -test was used to analyze the parameters of AA or AB (cid:49) BB carriers except for triglycerides, which were analyzed by Mann-Whitney U test. Multivar- iate logistic regression analyses were performed on PONA genotypes, sex, age, systolic and diastolic blood pressure, proportion of smokers, and serum total cholesterol.
An Economic Approach to Generalize Findings from Regression-Discontinuity Designs

Regression-discontinuity (RD) designs estimate treatment eﬀects at a cutoﬀ. This paper shows that much can be learned about average treatment eﬀects for the treated (ATT), untreated (ATUT), and population (ATE) if the cutoﬀ was chosen to maximize the gain from treatment, net of costs. The ATT must be positive and the RD estimate bounds the ATT from below and the ATUT from above, implying bounds for the ATE. Optimality of the cutoﬀ rules out constant treatment eﬀects. The treatment eﬀect must be increasing at the cutoﬀ, making cutoﬀ optimality testable. The theoretical results are applied to existing RD studies.
Efektivitas Kegiatan Praktikum terhadap Hasil Belajar Fisika Kelas X pada Materi Asas Black di SMA Muhammadiyah 4 Yogyakarta Tahun Ajaran 2015/2016

Abstract The aim of this research to study the effectiveness of practical activities to learn physics class X results on the principle of black in SMA Muhammadiyah Yogyakarta 4 2015/2016 academic year. The purpose of this study to determine the preparation and implementation of practical activities and to investigate the effectiveness of practical activities to learn physics class X results on the principle of black material. This study was an experimental study. The method used in this study Pre-Experimental with One-group pretest-posttest design. Subjects of research include teachers and students in grade 4 X.C SMA Muhammadiyah Yogyakarta. Data collected by the test, questionnaire, observation, and interviews. In this study showed that the preparation and implementation of the principles black lab activities were apparent from the tools and materials used by 85.2% in both categories. While the initial implementation of related activities, processes, and final practicum activities obtained an overall average percentage of 90.27% senses good category. Practical activities effectively to the learning outcomes physics class X on the principle of black material. Keywords: effectively, Practical activities, the learning outcomes. Abstrak Penelitian tentang efektivitas kegiatan praktikum terhadap hasil belajar fisika kelas X pada materi asas black di SMA Muhammadiyah 4 Yogyakarta tahun ajaran 2015/2016. Tujuan penelitian ini untuk mengetahui persiapan dan pelaksanaan kegiatan praktikum serta untuk mengetahui efektivitas kegiatan praktikum terhadap hasil belajar fisika kelas X pada materi asas black. Penelitian ini merupakan penelitian eksperimen. Metode yang digunakan dalam penelitian ini Pre-Experimental dengan One- Group Pretest-Posttest Design. Subjek penelitian meliputi guru dan siswa kelas X.C SMA Muhammadiyah 4 Yogyakarta. Data dikumpulkan dengan tes, angket, observasi, dan wawancara. Pada penelitian ini diperoleh hasil bahwa persiapan dan pelaksanaan kegiatan praktikum asas black dilihat dari kondisi alat dan bahan yang digunakan sebesar 85,2% dengan kategori baik. Sedangkan pelaksanaan yang berkaitan dengan awal kegiatan, proses kegiatan dan akhir kegiatan praktikum diperoleh presentase rata-rata keseluruhan sebsesar 90,27% dengan kategori baik. Kegiatan praktikum efektif terhadap hasil belajar fisika kelas X pada materi asas black. Kata kunci: efektivitas, kegiatan praktikum, hasil belajar.
Prevalence of Pediatric Adherence Level to Asthma Medications International Journal of Community & Family Medicine

any indication of poor adherence, as worsening of asthma symptoms despite having an adequate treatment or recurrent hospitalizations. Goes hand in hand, detecting poor adherence early allow the physician to intervene early and avoid the unnecessary change in the medications or increasing the doses [6]. This study aims to assess adherence to asthma medications among pediatric population in Saudi Arabia, correlate poor adherence with the level of asthma control and investigate the factors that may influence the patient's adherence. annual estimated of non-adherence in United States about billion US dollars [15]. different long the side and the cost of the treatment, related the child's parents of education, knowledge about asthma, parent's Abstract Objective: To assess adherence to asthma medications among paediatric population in Saudi Arabia, correlate poor adherence with the level of asthma control and investigate the factors that may influence the patient's adherence. Methods: This Cross-sectional study will include 319 paediatric participants, they will be recruit from two paediatric asthma clinics at King Abdullah Medical City (KAMC) and Maternity and Children Hospitalin Makkah (MCHM) by using a valid Arabic translation of the 8-item Morisky medication adherence scale (MMAS-8). Results: The adherence rate among children by MMAS-8 identified in 35.1 % were low adherence rate, while medium adherence were 64.9%. The adherence rate significantly increased with the parent’s educational level among mothers (P-Value = <0.001) while the fathers is (P-Value = 0.004). Moreover, the prevalence of parents concern about asthmatic medication side effects of long-term usage are 56.7% while 43.3% of parents are not. Conclusion: The studies in Saudi Arabia showed high prevalence of asthma among children and a high rate of poor asthma control, yet no studies was conducted to assess the rate of pediatric adherence to asthma medication also the burden of the problem of “non-adherence” among asthmatic children in terms of medical complications, educational problems and health-care cost. In general, studies showing the benefits of strict adherence to asthma medication, in form of better control of asthma symptoms as well as decrease in asthma morbidity and mortality.
Healthy Subjects Patients with Multiple Sclerosis Than in Proteolipid Protein Occur More Often in Encephalitogenic Region of Myelin Surges of Increased T Cell Reactivity to an

We have previously shown that patients with multiple sclerosis (MS) have increased T cell responses to the immunodominant region (residues 184–209) of myelin proteolipid protein (PLP). The present study investigated whether this reactivity ﬂuctuates over time and correlates with disease activity. We performed monthly limiting dilution assays for 12–16 mo in four healthy subjects and ﬁve patients with relapsing-remitting MS to quantify the frequencies of circulating T cells proliferating in response to PLP 41–58 , PLP 184–199 , PLP 190–209 , myelin basic protein (MBP), MBP 82–100 , and tetanus toxoid. Disease activity was monitored by clinical assessment and gadolinium-enhanced magnetic resonance imaging of the brain. There were ﬂuctuations in the frequencies of autoreactive T cells in all subjects. Compared with healthy controls, MS patients had signiﬁcantly more frequent surges of T cells reactive to the 184–209 region of PLP, but infrequent surges of T cell reactivity to MBP 82–100 . There was temporal clustering of the surges of T cell reactivity to MBP 82–100 and MBP, suggesting T cell activation by environmental stimuli. Some clinical relapses were preceded by surges of T cell reactivity to PLP 184–209 , and in one patient there was signiﬁcant correlation between the frequency of T cells reactive to PLP 184–199 and the total number of gadolinium-enhancing magnetic resonance imaging lesions. However, other relapses were not associated with surges of T cell reactivity to the Ags tested. T cells reactive to PLP 184–209 may contribute to the development of some of the
ANEMIA IN PREGNANT WOMEN IN ARAR, NORTHERN SAUDI ARABIA

Background: Anemia are important risk factors for the health and development of women as well as in the neonates. Anaemia affects one-quarter of the world’s population and is concentrated in preschool-aged children and women, making it a global public health problem. Anemia is pregnancy has become an important public health issue. Objectives: To find out the prevalence of anemia and evaluate its association with multiparty in pregnant women attending the Maternity and children Hospital of Arar, Northern Saudi Arabia. Methods: A descriptive cross-sectional study of one 299 cases of pregnant women who came to Maternity and children Hospital of Arar, Northern Saudi Arabia, for antenatal checkup. The data was collected on a structured proforma which was evaluated subsequently. Results : In a total of 299 cases, there 55.5%) of the studied women (46.2%) had 2-3 children, 11.7% were primigravid and 17.4% had > 5 children. The total prevalence of Lab. diagnosed anemia among the studied pregnant women was 34.8%. Mild anemia (10-11 g/dL) was found in 26.8%, moderate anemia (7.0–9.9 g/dL) in 7.0% and severe anemia (Hb of <7 g/dL or less) in 1% of the total pregnant women, but Unknown Hb level was reported by 24.1%. There was insignificant association between lab. diagnosed anemia and parity as 53.3% cases of primigravida were suffering from anemia while in women who have 3-5 children 53.3% were anemic and multiparous (having >5children) women revealed slight increased risk of anemia with the figure of 41.5%. Conclusion: Anemia is quite common in the pregnant women of this region. There is slightly increased risk of anemia in primigravida as compared to multiparous female. The data highlighted the importance of iron supplements for expecting mothers and raised the need of awareness programs for the community in this regard.