Miracle-dz/UniFAR-FTUs huggingface dataset:
PERCIEVED BARRIERS TO PHYSICAL ACTIVITY

Background: Perceived barriers to moderate-to-vigorous physical activity (MVPA) may contribute to the low rates of MVPA in adolescents. We examined the psychometric properties of scores from the Perceived Barriers to MVPA scale (PB-MVPA) by examining composite reliability and validity evidence based on the internal structure of the PB-MVPA and relations with other variables. Methods: This study was a cross-sectional analysis of data collected in 2013 from adolescents (N=507; Mage=12.40, SD=.62) via self-report scales. Results: Using exploratory and confirmatory factor analyses, we found that perceived barriers were best represented as two factors representing internal (e.g., “I am not interested in physical activity”) and external (e.g., “I need equipment I don’t have”) dimensions. Composite reliability was over . 80. Using multiple regression to examine the relationship between perceived barriers and MVPA, we found that perceived internal barriers were inversely related to MVPA (β=-.32, p<.05). Based on results of the analysis of variances, there were no known-group sex differences for perceived internal and external barriers (p>.26). Conclusions: The PB-MVPA scale demonstrated evidence of score reliability and validity. To improve the understanding of the impact of perceived barriers on MVPA in adolescents, researchers should examine internal and external barriers separately.
UDC 612.394-054 Comparable characteristics of biologically driven eating behavior in diff erent ethnic groups of medical students

Methods: The study group includes 209 respondents who are foreign students (aged 17 to 28) who studied in LNMU while residing in dormitories or rented apartments. Participants were surveyed using the English version of the Dutch Eating Behavior Questionnaire DEBQ (Van Strien et al., 2002) and additional original questions about nutritional interventions for healthy food habits. BMI was calculated based on self-reported height and weight. Statistical analysis with JAMOVI provided Cronbach’s α coeffi cient analysis with determination of confi dence interval – 95%СІ.
Zona de manejo para preparo do solo na cultura da cana-de-açúcar

Soil compaction influences all stages of crop growth, but in many low yield sugarcane fields critical levels and effects of soil compaction are ignored. Therefore, identifying localization and intensity of compaction are very relevant for descompactation of soil. In this context, this study aimed to apply three criteria for delineating zones for soil compaction management: soil layer where first appear values of soil penetration resistance considered critical for sugarcane growth; cone index for 0-40 cm layer, and depth of occurrence of maximum soil penetration resistance. Sampling was carried out in a grid with 113 points spaced at 100 m, georeferenced by means of a Global Positioning System receiver. Soil penetration resistance in eight layers of 5 cm depth, cone index and depth of occurrence of maximum penetration resistance were determined from data gathered by an automatic measuring penetrometer. Estimative of non-sampled values were obtained by means of kriging interpolation, which allowed drawing of contour maps and the definition of four regions in the field for site specific subsoiling.
OP-EJEC170144 654..659

Cardiology Unit, Azienda Ospedaliero-Universitaria di Ferrara, Cona, (FE), Italy; Division of Cardiology, Department of Diagnostics, Clinical and Public Health Medicine, University of Modena and Reggio Emilia, Policlinico d Modena, Italy; Heart and vascular institute, Cleaveland Clinic, Cleaveland, USA; Cardiology Unit, Maria Cecilia Hospital, GVM Care & Research, Cotignola, Italy; and Maria Cecilia Hospital, GVM Care & Research, E.S. : Health Science Foundation, Cotignola, Italy
Rapid GC-MS Analysis of Pesticide Residues Using Analyte Protectants

Abstract A multi-residue method was developed to determine pesticides in foods using analyte protectants to compensate for matrix effects. Promising analyte protectants and combinations of these analyte protectants were evaluated for masking active sites in gas chromatography systems. The optimal combination of analyte protectants was determined to be the mixture of polyethylene glycol and olive oil. Calibration curves for analyte protectants in both neat solvents and matrix-matched standards were compared and similar response enhancement was observed. This result suggests a convenient calibration method using a combination of analyte protectants in neat solvent instead of the conventional matrix-matched standards calibration method.
Alliance Rupture: an unsuccessful case of psychoanalytic psychotherapy with a borderline patient

This paper aims to understand the processes of rupture of the Therapeutic Alliance (TA) of a case of interrupted psychoanalytic psychotherapy (PP) with a patient with Borderline Personality Disorder (BPD). This is a systematic case study that comprises 15 sessions of PP, one patient with complaints of impulsiveness and difficulties in interpersonal relationships, and his female therapist. The sessions were videotaped and transcribed. The identification of ruptures was made by the Rupture Resolution Rating System (3R's). There were 100 ruptures of AT, of these 69% were withdrawal ruptures and 31% of confrontation. We found 30 contributions from therapist to ruptures. The withdrawal ruptures are more subtle and difficult to identify, occurring more frequently than those of confrontation in the treatment. In the case of patients with BPD, therapists should develop skills to make interventions focused on TA. The need for other studies that seek to replicate the research in other cases of success and therapeutic failure is highlighted.
The Impact of Pro-Poor Reforms on Consumers and the Water Utility in Maputo, Mozambique

Over one billion people gained access to piped water between 2000 and 2015. Piped water access in sub-Saharan Africa (SSA), however, is the lowest of all SDG regions and is declining: in 2017, only 56% of the urban population in SSA had access to piped water in their homes, down from 65% in 2000. Increasing water access via private connections is difficult for many of utility providers in SSA, and unconnected households may also choose not to connect to the water utility network because of low-quality utility service, high water charges and high connection fees. This paper focuses on understanding the impact of the pro-poor water reforms implemented between 2010 and 2019 in the Greater Maputo Area (GMA), Mozambique; specifically, it attempts to understand how households were able to obtain piped water access through a water connection campaign, a reduction of the connection fee, and the option of paying in instalments. We use data collected in 2010 and 2012 – before and after these policy changes were introduced – from 1300 households in 6 poor neighbourhoods in peri-urban Maputo. This paper also investigates the broader sectoral impacts of these policies over time from the water utility’s perspective, using data from sector reports and interviews with key informants that were conducted by one of the authors in 2019. We found that between 2009 and 2017, the number of domestic private connections more than doubled in the GMA. Both the utility connection campaign and the reduction in connection fees facilitated water access for low-income households – although the poorest households were still unable to access piped water in the studied neighbourhoods – and for a few households, access was made possible by the option of paying the connection fee in instalments. Such rapid increases in the number of connections had two important implications for the water sector: first, as the number of private connections increased, the quality of service decreased significantly; second, the increase in domestic connections among largely low-income and relatively low-consuming customers resulted in major financial challenges for the system. These results are in line with those of other authors who argue that social and financial goals cannot be achieved in tandem; they also support findings in the existing literature on the limited ability of tariffs to deliver subsidies to the poor.
Prevalence of maxillofacial fractures in hospital patients: A five year retrospective study

1. Department of Oral and Maxillofacial Surgery, Alborz University of Medical Sciences, Karaj, Iran 2. Dental Clinical Research Development Unit, Alborz University of Medical Sciences, Karaj, Iran 3. Department of neurosurgery, Shahid madni hospital, Alborz University of Medical Sciences, karaj, Iran 4. Department of Epidemiology and Biostatistics, Dental School, Tehran University of Medical Sciences, Tehran, Iran 5 Department of Surgery, Shahid Madni hospital, Alborz University of Medical Sciences, karaj, Iran 6. Student Research Committee, Alborz University of Medical Sciences, Karaj, Iran
Theorising and Modeling Interface Design Quality and its Predictive Influence on Learners’ Post Adoption Behaviour in E-Learning Course Environments

The current study, guided by the cross-sectional survey method, assessed interface design quality, and its predictive ability on E-learners’ post-adoption behavior in E-learning course environments. DeLone and McLean’s Information Systems Success Model, Khan’s E-learning Framework, and Bhattacherjee’s Information System Continuance Model formed the current study's theoretical underpinning. Data for the study were collected from 232 E-learners in selected Ugandan higher learning institutions, using a 38-item self-administered questionnaire. Principal Components Analysis produced a four-factor structure of interface design quality that comprised of content interactivity, accessibility design, system navigation, and visual-aesthetics design, which were found to be valid and reliable using Confirmatory Factor Analysis. The Structural Equation Model fit indices revealed that the hypothesised model achieved adequate goodness-of-fit to the data. Regarding the structural relationships, the four factors were found to be statistically significant predictors of E-learners’ satisfaction; and in-turn, satisfaction impacted learning agility. The results have clearly aligned with the study's theoretical framework, buttressing existing empirical data on interface designs and end-user post adoption with E-learning interventions. The current study is crucial for making evidence-based pedagogical and design decisions by key E-learning stakeholders for the successful implementation and continued use of digital learning solutions in higher education contexts.
Lime and phosphorus effects on the dry matter production of eragrostis curvula on dystrophic clay soils

Abstract The dry matter yield responses of Eragrostis curvula to P and lime over two seasons on Balmoral and Balgowan soil series in the Natal Mistbelt are discussed. With this work forming part of a study aimed at characterizing P fixation in these soils, P (0, 100, 300 and 600 kg P/ha) and lime (0, 2 000 and 6 000 kg/ha as calcium hydroxide), were applied three years prior to establishment of E. curvula. Highly significant yield responses to P were noted, P effects being particularly dramatic at establishment, when response continued to the highest P level. Yields over the two seasons were closely related to soil test (AMBIC) values, with a threshold P test of 7mg/L being indicated. E. curvula displayed a remarkable ability to tolerate soil acidity, and yield responses to lime, although significant, were not nearly as marked as responses to P. In the absence of lime, where acidity was severe (pH[KCl] = 3,8 to 3,9; soil acid saturation = 60 to 80 %) yields were 87 to 97 % of those attained with the highe.
Exercise combined with trimetazidine improves anti-fatal stress capacity through enhancing autophagy and heat shock protein 70 of myocardium in mice

Background: Anti-stress capacity is important to resist the occurrence of adverse events. To observe the effects of exercise, trimetazidine alone or combined on the anti-stress capacity of mice, and further explore its potential mechanism. Methods: Forty-four C57BL/6 male mice aged 8 weeks were randomly divided into four groups (n=11 for each group): control group (group C), exercise group (group E), trimetazidine group (group T), exercise combined with trimetazidine group (group TE). After the intervention, each group was randomly subdivided into the exhaustive exercise (EE, n=6) and the non-EE (n=5) subgroups. The mice in the EE-subgroup underwent EE. Mice were sacrificed 12 hours later after EE. The myocardial ultrastructure and autophagosomes were observed under an electron microscope. The expression of autophagy-related proteins: BNIP3, LC3-II, and P62 were analyzed and the heat shock protein 70 mRNA transcription and protein expression were also investigated. Results: Exercise or trimetazidine increased the expression of BNIP3, LC3-II, and heat shock protein 70, decreased the expression of P62 pre- and post-EE while the combination has the synergistic effect. Conclusion: Exercise and trimetazidine, alone or combined enhanced the anti-stress capacity of mice significantly. The underlying mechanism may be associated with the promotion of autography and the expression of heat shock protein 70.
SPECTRAL ALGEBRAIC GEOMETRY

1.1. A motivating example: elliptic cohomology theories. Generalized cohomology theories are functors which take values in some abelian category. Traditionally, we consider ones which take values in abelian groups, but we can work more generally. For instance, take cohomology theories which take values in sheaves of graded abelian groups (or rings) on some given topological space, or in sheaves of graded OS-modules (or rings) on S, where S is a scheme, or possibly a more general kind of geometric object, such as a Deligne-Mumford stack , and OS is its structure sheaf. Given a scheme (or Deligne-Mumford stack) S, it is easy to construct an example of a cohomology theory taking values in graded OS-algebras; for instance, using ordinary cohomology, we can form F∗(X) := ( U 7→ H(X,OS(U)) ) ,
Downregulation of death receptor 4 is tightly associated with positive response of EGFR mutant lung cancer to EGFR-targeted therapy and improved prognosis

Death receptor 4 (DR4), a cell surface receptor, mediates apoptosis or induces inflammatory cytokine secretion upon binding to its ligand depending on cell contexts. Its prognostic impact in lung cancer and connection between EGFR-targeted therapy and DR4 modulation has not been reported and thus was the focus of this study. Methods: Intracellular protein alterations were measured by Western blotting. Cell surface protein was detected with antibody staining and flow cytometry. mRNA expression was monitored with qRT-PCR. Gene transactivation was analyzed with promoter reporter assay. Drug dynamic effects in vivo were evaluated using xenografts. Gene modulations were achieved with gene overexpression and knockdown. Proteins in human archived tissues were stained with immunohistochemistry. Results: EGFR inhibitors (e.g., osimertinib) decreased DR4 levels only in EGFR mutant NSCLC cells and tumors, being tightly associated with induction of apoptosis. This modulation was lost once cells became resistant to these inhibitors. Increased levels of DR4 were detected in cell lines with acquired osimertinib resistance and in NSCLC tissues relapsed from EGFR-targeted therapy. DR4 knockdown induced apoptosis and augmented apoptosis when combined with osimertinib in both sensitive and resistant cell lines, whereas enforced DR4 expression significantly attenuated osimertinib-induced apoptosis. Mechanistically, osimertinib induced MARCH8-mediated DR4 proteasomal degradation and suppressed MEK/ERK/AP-1-dependent DR4 transcription, resulting in DR4 downregulation. Moreover, we found that DR4 positive expression in human lung adenocarcinoma was significantly associated with poor patient survival. Conclusions: Collectively, we suggest that DR4 downregulation is coupled to therapeutic efficacy of EGFR-targeted therapy and predicts improved prognosis, revealing a previously undiscovered connection between EGFR-targeted therapy and DR4 modulation.
Chemical composition of the volatile oil of Chenopodium ambrosioides L. from Mianyang in Sichuan Province of China and its sub-chronic toxicity in mice

Purpose: To determine the chemical constituents of the volatile oil of Chenopodium ambrosioides L. from Mianyang in Sichuan Province of China, and assess the sub-chronic toxicity of the volatile oil in mice.Methods: The volatile chemical components were analyzed by gas chromatography-mass spectrometry (GC-MS). Sixty Kunming mice were divided into six groups of ten mice each. One group served as control (no treatment), two groups were orally administered ρ-cymene at doses of 3 and 7 mg/kg, respectively, for 27 days, while three groups received the volatile oil at doses of 10, 25 and 40 mg/kg, respectively, for the same duration. Sub-chronic toxicity in the mice was evaluated by observing their general behavior, measuring serum levels of aspartate transaminase (AST) and alanine transaminase (ALT), evaluating liver, heart, kidney and thymus indices, and assessing the histological morphology of the organs.Results: The volatile oil contained 14 chemical components, of which α-terpinene and ρ-cymene accounted for 32.89 and 24.25 %, respectively. The volatile oil caused significant (p < 0.05) increase in liver index, and serum AST and ALT levels, and also induced distinct morphological changes in mouse liver, heart and kidney.Conclusion: The main volatile components of the oil are α-terpinene and ρ-cymene. The volatile oil showed dose-dependent toxicity in mice, thus lending some support for the safe use of C. ambrosioides in traditional medicine. Keywords: Chenopodium ambrosioides, Volatile oil, Oral toxicity, AST and ALT, Histopathological changes
PII: S0038-0717(01)00013-X

We studied soil moisture dynamics and nitrous oxide (N2O) ̄uxes from agricultural soils in the humid tropics of Costa Rica. Using a splitplot design on two soils (clay, loam) we compared two crop types (annual, perennial) each unfertilized and fertilized. Both soils are of andic origin. Their properties include relatively low bulk density and high organic matter content, water retention capacity, and hydraulic conductivity. The top 2±3 cm of the soils consists of distinct small aggregates (dia. ,0.5 cm). We measured a strong gradient of bulk density and moisture within the top 7 cm of the clay soil. Using automated sampling and analysis systems we measured N2O emissions at 4.6 h intervals, meteorological variables, soil moisture, and temperature at 0.5 h intervals. Mean daily soil moisture content at 5 cm depth ranged from 46% water ®lled pore space (WFPS) on clay in April 1995 to near saturation on loam during a wet period in February 1996. On both soils the aggregated surface layer always remained unsaturated. Soils emitted N2O throughout the year. Mean N2O ̄uxes were 1.04 ^ 0.72 ng N2O-N cm 22 h (mean ^ standard deviation) from unfertilized loam under annual crops compared to 3.54 ^ 4.31 ng N2O-N cm 22 h from the fertilized plot (351 days measurement). Fertilization dominated the temporal variation of N2O emissions. Generally ̄uxes peaked shortly after fertilization and were increased for up to 6 weeks (`post fertilization ̄ux'). Emissions continued at a lower rate (`background ̄ux') after fertilization effects faded. Mean post-fertilization ̄uxes were 6.3 ^ 6.5 ng N2O-N cm 22 h while the background ̄ux rate was 2.2 ^ 1.8 ng N2O-N cm 22 h. Soil moisture dynamics affected N2O emissions. Post fertilization ̄uxes were highest from wet soils; ̄uxes from relatively dry soils increased only after rain events. N2O emissions were weakly affected by soil moisture during phases of low N availability. Statistical modeling con®rmed N availability and soil moisture as the major controls on N2O ̄ux. Our data suggest that small-scale differences in soil structure and moisture content cause very different biogeochemical environments within the top 7 cm of soils, which is important for net N2O ̄uxes from soils. q 2001 Elsevier Science Ltd. All rights reserved.
Transmitting Information About Crime and Crime Prevention to Citizens: The Evanston Newsletter Quasi-Experiment

Paul J. Lavrakas is an assistani professor of journalism and director of urban affairs at the Center for Urban Affairs and Policy Research, Northwestern University, 2040 Sheridan Road, Evanston, 1L 60201. He received a B. A. in social sciences from Michigan State University, an M. A. in experimental social psychology from Loyola University of Chicago, and a Ph.D. in applied social psychology from Loyola University of Chicago. Dr. Lavrakas' main area of interest is community crime prevention research and evaluation, including citizens' protective reactions to crime and fear of crime. Dennis P. Rosenbaum is a research psychologist and assistant professor at the Center for Urban Affairs and Policy Research, Northwestern University, 2040 Sheridan Road, Evanston, IL 60201. He received a B.A. in psychology fromClairmonl Mens College, an MA. in social psychology from the University of Waterloo, and a Ph.D. in applied social psychology from Loyola University of Chicago. Dr. Rosenbaum's areas of interest include research and evaluation of police/community anti-crime programs, employee theft programs, youth gang and delinquency research, and research on the psychology of victimization. Frank Kaminski is a planning/research officer in the Division of Coordination and Consultation, Evanston Police Department, 1454 Elmwood, Evanston, IL 60204. He received his B.A. in criminal justice from the University of Illinois and his M. A. in public administration from Roosevelt University. Officer Kaminski's main areas of interest include community crime prevention programming and police planning and policy formulation.
Reduced miR-16 levels are associated with VEGF upregulation in high-risk myelodysplastic syndromes

Objective: Overexpression of vascular endothelial growth factor (VEGF), a major angiogenic factor, was found in myelodysplastic syndromes (MDS) and showed different expression statuses in different risk groups of MDS. We aimed to investigate the possible role of microRNA (miR)-15a and miR-16 on the regulation of VEGF expression and their effect on angiogenesis in lower- and higher-risk MDS. Methods: We studied peripheral blood and bone marrow samples of MDS patients or several leukaemia and MDS cell lines by enzyme-linked immunosorbent assay, immunohistochemical staining, immunofluorescence and quantitative PCR for expression levels of VEGF, miR-15a and miR-16. MiRNA transfection and Luciferase reporter assays were conducted to investigate whether VEGF is a target of miR-16. Migration and tube formation assays were performed in cells exposed to medium from cells with overexpressed or knockdown miR-16. Results: It showed a significantly lower level of miR-16 in higher-risk MDS patients, while the VEGF levels were upregulated. Inverse correlation between VEGF and miR-16 were determined in cells lines including SKM-1, THP-1, and K562 cells. Overexpression of miR-16 in SKM-1 cells resulted in reduced VEGF secretion and cell protein levels. Direct binding of miR-16 to the 3' untranslated region (3'-UTR) of VEGF was confirmed by luciferase reporter assays. The migration and tube formation of human umbilical vein endothelial cells decreased in the presence of medium from SKM-1 cells with overexpressed miR-16. Conclusion: These data suggest that miR-16 may play a role in angiogenesis in higher-risk MDS by targeting VEGF and therefore modulating MDS progression. MiR-16 might be a novel therapeutic target in higher-risk MDS.