Miracle-dz/UniFAR-FTUs huggingface dataset:
Being a Mother, Student, and Educator: Graduate Student-Mothers' Parenting Experience During COVID-19 Pandemic

COVID-19 pandemic has been a life-changing experience in many families, affecting parents whose current responsibilities are not only being caregivers, but also educators to their children who are forced to learn from home. This situation deeply affects student mothers who have multiple roles at home, which are maintaining a postgraduate study, being housewives, and accompanying their children in online learning. This study aims to explore the lived experience of student mothers in parenting their school-age children during the pandemic, which is viewed from the quality of parenting (positive and negative parenting) and parenting stress perceived by mothers during the home learning activities. The participants were four mothers who are currently undergoing postgraduate study and have children enrolled in kindergarten and primary school (grade 1-3), and learning from home during the pandemic. The method used is qualitative, with an exploratory approach. The data were obtained through online semi-structured interviews and processed using thematic analysis methods. There are 7 themes emerged from the results, which are: 1) balancing multiple responsibilities, 2) experience in educating children from home, 3) adjusting parent expectations, 4) changes in social relationships , 5) agreements about screen time, 6) eating behaviors and physical exercises, 7) setting up new routine. These themes which will be discussed further, along with their implications for the parents’ psychological well-being.
Review on Phyto-chemistry and pharmacological activity of Melia azedarach

: Medicinal plants as essential additives in foods, beverages, and medications have been a part of human culture since the dawn of time. Medicinal plants' nutritional, pharmacological, biological, and toxicological characteristics have numerous applications in numerous industries. Nowadays, most people rely on complementary and alternative therapies to treat various illnesses derived from natural sources. Melia azedarach is one of the plants (Meliaceae family) grown in numerous Indian states. The entire plant or its parts (leaves, stem and roots) have medicinal characteristics and have been used by native and tribal people in various parts of India for a very long time. This plant has traditionally been used to cure various conditions, including piles, itching, asthma, leprosy, and cough. The current study includes a comprehensive analysis of its systematic botanical position, phytochemical analysis, research on the plant's pharmacological activity, and medicinal applications.
Peg-Grafted Liposomes for L-Asparaginase Encapsulation

L-asparaginase (ASNase) is an important biological drug used to treat Acute Lymphoblastic Leukemia (ALL). It catalyzes the hydrolysis of L-asparagine (Asn) in the bloodstream and, since ALL cells cannot synthesize Asn, protein synthesis is impaired leading to apoptosis. Despite its therapeutic importance, ASNase treatment is associated to side effects, mainly hypersensitivity and immunogenicity. Furthermore, degradation by plasma proteases and immunogenicity shortens the enzyme half-life. Encapsulation of ASNase in liposomes, nanostructures formed by the self-aggregation of phospholipids, is an attractive alternative to protect the enzyme from plasma proteases and enhance pharmacokinetics profile. In addition, PEGylation might prolong the in vivo circulation of liposomes owing to the spherical shielding conferred by the polyethylene (PEG) corona around the nanostructures. In this paper, ASNase was encapsulated in liposomal formulations composed by 1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC) or 1,2-dimyristoyl-sn-glycero-3-phosphocholine (DMPC) containing or not different concentrations of 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N [methoxy (polyethylene glycol)-2000] (DSPE-PEG). Nanostructures of approximately 142–202 nm of diameter and polydispersity index (PDI) of 0.069 to 0.190 were obtained and the vesicular shape confirmed by Transmission Electron Microscopy (TEM and cryo-TEM). The encapsulation efficiency (%EE) varied from 10% to 16%. All formulations presented activity in contact with ASNase substrate, indicating the liposomes permeability to Asn and/or enzyme adsorption at the nanostructures’ surface; the highest activity was observed for DMPC/DSPE-PEG 10%. Finally, we investigated the activity against the Molt 4 leukemic cell line and found a lower IC50 for the DMPC/DSPE-PEG 10% formulation in comparison to the free enzyme, indicating our system could provide in vivo activity while protecting the enzyme from immune system recognition and proteases degradation.
Implementasi Kurikulum Merdeka untuk Meningkatkan Motivasi Belajar pada Sekolah Menengah Kejuruan Pusat Keunggulan

Kurikulum merupakan sebuah wadah yang akan menentukan arah pendidikan. Untuk pelaksanaan pembelajaran Kurikulum merdeka menekankan tercapainya kompetensi sikap, pengetahuan dan keterampilan. SMKN 1 Tana Toraja merupakan sekolah yang mengimplementasikan Kurikulum merdeka dalam pembelajaran. Implementasi Kurikulum merdeka diharapkan dapat meningkatkan motivasi belajar siswa, karena kurikulum ini pada dasarnya berpusat pada siswa. Guru hanya sebagai fasilitator dan mediator serta motivator bagi siswa, agar siswa semangat dalam belajar dan mendapat hasil baik. Metode penelitian yang di gunakan adalah Penelitian ini menggunakan metode penelitian lapangan, dengan pendekatan kualitatif dan mengambil latarbelakang di SMKN 1 Tana Toraja. Subjek dalam penelitian ini adalah Waka Kurikulum, Guru dan siswa, Pembelajaran yang baik adalah bersifat menyeluruh dalam melaksanakannya dan mencakup berbagai aspek, baik aspek kognitif, afektif maupun psikomotorik, sehingga dalam pengukuran peningkatan dari hasil keberhasilannya selain dilihat dari segi kuantitas juga dari kualitas yang telah dilakukan di sekolah-sekolah apa yang ingin dicapai melalui inovasi pendidikan tersebut, yaitu usaha untuk mengubah proses pembelajaran, perubahan dalam situasi belajar yang menyangkut kurikulum, peningkatan fasilitas belajar mengajar serta peningkatan mutu profesional guru.Mengacu pada pendapat tersebut, maka penerapan merdeka dalam pembelajaran, yang mana pembelajaran yang aktif harus ditandai adanya rangkaian terencana yang melibatkan siswa secara langsung, komprehensif, baik fisik, mental maupun emosi. Hal ini sering diabadikan oleh guru, karena guru lebih mementingkan pada pencapaian tujuan dan target kurikulum. Salah satu upaya guru dalam menciptakan suasana aktif, efektif dan menyenangkan dan pembelajaran harus berpusat pada siswa, sehingga dalam proses pembelajaran yakni dengan menggunakan metode-metode yang tepat dan alat media. Hal ini dapat membantu guru dalam menggerakkan, menjelaskan gambaran ide dari suatu materi yang sesuai dengan kurikulum merdeka. Hasil penelitian ini dapat disimpulkan bahwa Implementasi Kurikulum merdeka dalam meningkatkan motivasi belajar siswa pada mata pelajaran sudah berjalan dengan semestinya dan mengalami peningkatan selama persemesternya.
Joining particle and fluid aspects in streamer simulations

• A submitted manuscript is the author's version of the article upon submission and before peer-review. There can be important differences between the submitted version and the official published version of record. People interested in the research are advised to contact the author for the final version of the publication, or visit the DOI to the publisher's website. • The final author version and the galley proof are versions of the publication after peer review. • The final published version features the final layout of the paper including the volume, issue and page numbers.
E-procurement adoption in Indonesian government: A study of TOE model

Due to innovations, the Industrial Revolution 4.0 has become a popular trend among the public. The Indonesian government is eager to implement e-procurement in accordance with Presidential Regulation No. 16 of 2018 on government procurement. The purpose of this study is to assess the impact of each TOE model factor on Indonesian e-procurement adopters, as well as to investigate how the diffusion of innovation theory categorizes them. This study employed a quantitative method and SmartPLS version 3.0 to examine the model, based on Teo et al. (2009), which set the major structure. In this study, state-owned firms and their subsidiaries, as well as other private enterprises that operate in the infrastructure and construction sectors and participate in Indonesia’s e-procurement system, were used as samples. The result show that top management support (β = 0.279; p &lt; 0.05) and information sharing culture (β = 0.783; p &lt; 0.05) have positive and significant effects on e-procurement adoption. On the other hand, perceived cost (β = 0.097; p &gt; 0.05), firm size (β = –0.080; p &gt; 0.05), and business partner influence (β = –0.057; p &gt; 0.05) did not contribute any effect significantly. This study expects that the organizing committee for government goods and services procurement, as well as participants in government goods and services procurement, would pay attention to and consider significant components in the implementation of e-procurement outside of the applicable legislation.
A fundamental test for physics: the galactic supermassive obscure bodies

The problem of the enormous gravitational effects observed by the astronomers in several galactic nuclei with obscure bodies appears puzzling. These bodies are too large to be neutron stars generated by supernovae of primeval stars and are too small to be considered a new kind of obscure galaxies. This contradiction represents a fundamental test which might destroy the established gravitational theories. We present a new physical paradigm which substitutes the old "gravitational mass" guessed by Newton more than tree centuries ago.
Asteroid Family Physical Properties

An asteroid family is typically formed when a larger parent body undergoes a catastrophic collisional disruption, and as such family members are expected to show physical properties that closely trace the composition and mineralogical evolution of the parent. Recently a number of new datasets have been released that probe the physical properties of a large number of asteroids, many of which are members of identified families. We review these data sets and the composite properties of asteroid families derived from this plethora of new data. We also discuss the limitations of the current data, and the open questions in the field.
Vibrio Dynamics and Health Status of Pacific White Shrimp Fed with Cinnamaldehyde-Containing Feed

Highlight Research Cinnamaldehyde for shrimp Dynamics of Vibrio and the correlation with shrimp health status Green and yellow Vibrio bacteria in water, intestine, and hepatopancreas of shrimp Cinnamaldehyde decrease the number of green Vibrio bacteria Abstract Disease can cause shrimp mortality and high economic losses caused by Vibriosis group. One alternative is using cinnamaldehyde which function as an anti-microbial and inhibit the production of toxins released by microorganisms. This study aimed to evaluate the administration of cinnamaldehyde on the dynamics of Vibrio bacteria and the health status of Pacific white shrimp fed with cinnamaldehyde-containing feed. This study used a completely randomized design (CRD) consisted of 4 treatments and 3 replications consisting of treatment K, A, B, and C which mean feeding without cinnamaldehyde, feeding containing cinnamaldehyde dose of 0.05%, 0.1%, and 0.2% respectively. Parameters included total bacteria (green and yellow Vibrio) in water, intestine, and hepatopancreas, as well as immune responses parameters, including total hemocyte count (THC), respiratory burst (RB), and phenol-oxidase (PO). All data were tabulated in Microsoft Excel 2016 and all statistical analysis was conducted in the SPSS v.22. 0 software with one-way ANOVA followed by Duncan Multiple Range Test (DMRT (P=0.05). The results showed that the administration of cinnamaldehyde influences the dynamics of Vibrio and health status of shrimp. At the beginning and at the end of cinnamaldehyde administration, green and yellow Vibrio bacteria are mostly found in water, intestine, and hepatopancreas. The administration of cinnamaldehyde to Pacific white shrimp can reduce the number of green Vibrio bacteria both in the intestine and hepatopancreas as shown in treatments C and B. Cinnamaldehyde also affected the higher percentage of yellow Vibrio bacteria in treatments C and B compared to control (K). The highest immune responses of THC and RB were produced in treatments A and C compared to K. The decrease of green Vibrio bacteria and increased colonization of yellow Vibrio bacteria were correlated with immune responses. The best treatment in this study is treatment C.
Sex Differences in All-Cause Inpatient Mortality Risk in Gastric Cancer: Nationwide Inpatient Population-Based Study

Objective The purpose of this study is to evaluate the differences in demographic characteristics, comorbidities, and hospital outcomes in gastric cancer inpatients by sex and evaluate the risk factors for in-hospital mortality in gastric cancer inpatients by sex. Methods We conducted a cross-sectional study using the nationwide inpatient sample (NIS, 2019). Our sample included 22,415 adult inpatients (age ≥18 years) hospitalized with a primary discharge diagnosis of gastric cancer that was identified by the international classification of diseases, 10th revision (ICD-10) codes of C16.x. Independent univariate binomial logistic regression models were used to evaluate the odds ratio (OR) of predictors associated with all-cause in-hospital mortality in gastric cancer inpatients by sex. Results The total number of patients admitted with gastric cancer was 22,415, out of which 62.7% were males and 37.3% were females, with the mean age at the admission of 65.5 years and 66.4 years, respectively. While studying comorbidities, we found that 41.5% percent of all patients had gastric cancer with metastasis, and there existed a significantly higher prevalence in males (42.2% vs. 40.4% in females). Other important and statistically significant comorbid conditions that were prevalent in these patients include complicated diabetes (12.2%), obesity (12.1%), depression (8%), and alcohol abuse (3.1%). Females between 50-59 years of age were at 2.5 times increased risk of mortality compared to those less than 40 years of age (OR: 2.5; 95% CI: 1.28-4.95). Conclusion Females of the age group 50-59 years are at greater risk of all-cause inpatient mortality due to gastric cancer. Black males are at increased risk of all-cause inpatient mortality compared to White males. Gastric cancer incidence and mortality rates have been down trending with the development of screening and better treatment options, but it still continues to be a major burden on the healthcare system.
Intention to use novel methods of male directed contraception among college students

Purpose : Currently, men have two choices for contraception: the male condom and vasectomy. Male condoms have limited user efficacy, and vasectomies are not easily reversible. To supplement vasectomy and condom use, the World Health Organization has backed the urgent development of male-directed contraception (MDC). Using the Theory of Planned Behavior (TPB), this study was guided by the following aims: (1) describe college men’s attitudes, subjective norms, and perceived behavioral control towards male birth control methods and (2) determine if the following factors are associated with intention to use MDC methods: masculinity, attitudes, subjective norms, and perceived behavior control. Methods : This study used a cross-sectional design. Data were collected online, via email, from male college students at one Midwestern University. Results : Attitudes, subjective norms, and perceived behavioral control were statistically significant predictors of intention to use a male hormonal pill, transdermal gel, and hormonal injection. Attitudes and subjective norms were also found to be associated with intention to use a male birth control implant. Conclusion : These results suggest the TPB may be a suitable theory for further investigation into the intended use of MDC. Attitudes and subjective norms accounted for the most variability in intention to use MDC. Future research should therefore investigate specific attitudes and subjective norms that influence the intention to use developmental methods of MDC. Future research should also consider additional theoretical models, such as the Health Belief Model, to investigating to use developmental of
Zinc Oxide Nanoparticles as Potential Delivery Carrier: Green Synthesis by Aspergillus niger Endophytic Fungus, Characterization, and In Vitro/In Vivo Antibacterial Activity

We aimed to synthesize zinc oxide nanoparticles (ZnO NPs) using the endophytic fungal extract of Aspergillus niger. The prepared ZnO NPs were characterized, and their in vitro and in vivo antibacterial activity was investigated. Isolated endophytic fungus identification was carried out using 18S rRNA. A. niger endophytic fungal extract was employed for the green synthesis of ZnO NPs. The in vitro antibacterial activity of the prepared ZnO NPs was elucidated against Staphylococcus aureus using the broth microdilution method and quantitative real-time polymerase chain reaction (qRT-PCR). Additionally, the in vivo antibacterial activity was elucidated using a systemic infection model in mice. The biosynthesized ZnO NPs showed a maximum optical density at 380 nm with characteristic peaks on the Fourier-transform infrared spectrum. The X-ray diffraction pattern was highly matched with a standard platform of zinc oxide crystals. Energy-dispersive X-ray analysis confirmed that the main composition of nanoparticles was zinc and oxygen atoms. Scanning and transmission electron microscopies showed spherical geometry with a smooth surface. Zeta potential measurements (26.6 ± 0.56 mV) verified the adequate stability of ZnO NPs. Minimum inhibitory concentrations of ZnO NPs against S. aureus isolates ranged from 8 to 128 µg/mL. Additionally, ZnO NPs revealed antibiofilm activity, resulting in the downregulation of the tested biofilm genes in 29.17% of S. aureus isolates. Regarding the in vivo experiment, ZnO NPs reduced congestion and fibrosis in liver and spleen tissues. They also improved liver function, increased the survival rate, and significantly decreased inflammatory markers (p < 0.05). ZnO NPs synthesized by A. niger endophytic fungus revealed a promising in vivo and in vitro antibacterial action against S. aureus isolates.
Salt, Not Always a Cardiovascular Enemy? A Mini-Review and Modern Perspective

Dietary salt intake is a long-debated issue. Increased sodium intake is associated with high blood pressure, leading to salt-sensitive hypertension. Excessive salt intake leads to arterial stiffness in susceptible individuals via impaired nitric oxide action and increased endothelin-1 expression, overactivity of the renal sympathetic nervous system and also via aldosterone-independent activation of the mineralocorticoid receptor. Salt restriction in such individuals reduces blood pressure (BP) values. The optimal level of salt restriction that leads to improved cardiovascular outcomes is still under debate. Current BP and dietary guidelines recommend low sodium intake for the general population. However, a specific category of patients does not develop arterial hypertension in response to sodium loading. In addition, recent research demonstrates the deleterious effects of aggressive sodium restriction, even in heart failure patients. This mini review discusses current literature data regarding the advantages and disadvantages of salt restriction and how it impacts the overall health status.
Effects of Organic Acid and Feed Restriction Intensity on the Performance and Immune Response of Broilers

experiments data analyzed the data. This study was performed to evaluate the effects of organic acid and feed restriction intensity on the performance and immune response of broilers. For this purpose, 540 one-day-old male broilers of Ross 308 strain were grown in a 3×3 factorial experiment with three levels of Globacid (0, 0.5, and 1 mL/L) and three levels of feed restriction intensity (0, 10, and 20%) in a completely randomized design with 9 experimental treatments, 6 replicates with 10 chickens in each replicate up to 42 days of age. The group containing Globacid (1 mL/L) and the restriction intensity of 10% had the highest significant difference compared to the control ( p <0.05). The highest thymus weight was observed in the treatments with Globacid levels of 0.5 and 1 mL/L, respectively ( p < 0.05). Also, the highest humoral immune response among the groups was seen in the group containing Globacid (1 mL/L) and the restriction intensity of 10% ( p < 0.05). The results of this study generally showed that increasing the level of organic acid together with reducing the intensity of dietary restriction can improve the performance and immune responses of broilers.
Description of a Neotropical gall inducer on Araceae: Arastichus, gen. nov. (Hymenoptera, Eulophidae) and two new species

A new genus of a Neotropical gall inducing tetrastichine eulophid on Araceae is described and confirmed using Ultraconserved Elements (UCE) phylogenomic data. Arastichus Gates, Hanson, Jansen-González & Zhang, gen. nov., includes two new species and one species transferred from Aprostocetus Westwood: A. capipunctata Gates, Hanson, Jansen-González & Zhang, sp. nov., A. gallicola (Ferrière), comb. nov., and A. gibernau, Gates, Hanson, Jansen-González & Zhang, sp. nov.
Interaction Between a Vortex and a Turbulent Boundary Layer. Part 1: Mean Flow Evolution and Turbulence Properties

An experimental study was conducted to examine the interaction between a single weak streamwise vortex and a two-dimensional turbulent boundary layer. Attention was focused on characterizing the effect of the boundary layer on the vortex, including the effects of a moderate adverse pressure gradient. Rapid growth of the vortex core was observed, and a flattening of the core shape occurred when the dimension of the core radius became comparable to the distance of the vortex center from the surface. Adverse pressure gradients caused an increase in the rate of core growth, and therefore, a stronger distortion of the core shape. Measurements of surface skin friction beneath the vortex and some of the Reynolds stresses are presented.
Infinite and Finite Block-Length FD Transmissions With Spatially-Correlated RIS Channels

The reconfigurable intelligent surface (RIS)-assisted wireless communication system is studied in this paper, where two full-duplex (FD) users simultaneously communicate with each other. The reception at each user is facilitated through a dedicated RIS. Owing to the geometry and placements of meta-atoms, the analysis incorporates spatial-correlation among the channels related to RIS. Using moment-matching approach, a new analytical framework is presented for spatially-correlated channels considering the optimal phase-shifts from RIS meta-atoms. The effects of residual self-interference (RSI), self-reflections and interference from the RIS of transmitting user are considered in the analysis. The expressions are derived for the outage probability and ergodic capacity for infinite block-length transmission, and for finite block-length transmission, the expressions are obtained for block-error rate (BLER), ergodic capacity and system goodput. To gain further insights, the expression for the asymptotic outage probability is also derived. The finding of this paper confirms the ability of RIS-assisted communication to counter the detrimental effects of self-interference in FD scenario, even in presence of spatial-correlation. The derived expressions are validated using the Monte-Carlo simulations.