Miracle-dz/UniFAR-FTUs huggingface dataset:
Come into Bloom: A Grounded Theory of Well-Being among Filipino University Students

Most studies in positive psychology focused on psychological factors and their impact on mental health based on Western models and quantitative approaches (Datu et al., 2018). Thus, there is a need to develop further the knowledge and application of concepts and theoretical models grounded in the lived experiences of the Filipino population. The present study utilized a grounded theory method to build a Filipino-based well-being model among university students. The BLOOMS Model of Well-being proposed that holistic well-being comprises five interconnected dimensions (Academic, Psycho-emotional, Physical, Social, and Spiritual). The study found that personal factors, social influences, and unexpected life events influenced well-being. Also, the study suggested that the following strategies enhanced well-being: building, leveraging, owning, opening, molding, and self-enhancing practices, leading to holistic growth. Data from this study can serve as a resource for further exploration of positive psychology and developing mental health policies and programs for university students.
A thermal finite line contact EHL model of a helical gear pair

A thermal finite line contact elastohydrodynamic lubrication (EHL) model is developed to study lubricated contact performance of a helical gear pair. Three typical engagement positions during a meshing cycle, i.e. the engage-in position, the engage-out position and the pitch point position are chosen to show effect of load, speed, and addendum modification on pressure distribution, film profile, temperature field, etc. Results show temperature rise increases as the load or the speed goes up. The temperature distribution when the gear pair engaging around the pitch point behaves like a V-shape with higher values at the end parts. For the case with a standard center distance, proper addendum modification, i.e., negative modification for the bigger gear and positive modification for the small gear is good for improving lubrication performance and the service life of the helical gear drive.
Field test of a permanent in-well fiber-optic seismic system

A deviated borehole was drilled and completed to test systems for deployment of permanent in-well three-component fiber-optic seismic sensors. Two systems were developed and tested for deployment of these sensors. The first system involved using a passive mandrel device to enable coupling of the sensors simply using the weight of the tubing. The second system involved use of an active mandrel that incorporates a spring-loaded pad device to isolate the sensor from the tubing vibration. In addition, reference wireline vertical-seismic-profile data were acquired both in the empty cased borehole and through the tubing at the same location as the fiber optic sensor. Analysis of the data showed that best results were obtained using the active design. Tubing-related resonances were noted on data acquired using the passive design, whereas the active design did a good job of discriminating among these undesirable signals.
‘Dual’ labour market? Patterns of segmentation in European labour markets and the varieties of precariousness

This article aims to empirically explore how European labour markets are segmented and who the outsiders are. The article moves beyond the dichotomous approach to understanding labour market division, often based solely on examining employment relationships. Taking a multi-dimensional approach to defining labour market precariousness, this study incorporates aspects such as income, job prospects and subjective insecurity. Latent Class Analysis is used on data taken from the 2015 European Working Conditions Survey to extend the traditional definition of outsider-ness. Four labour market segments are found: insiders and three different types of outsiders: typical outsiders, dead-end insiders and subjective outsiders. Looking at the cross-national aspect, variations are found in the segmentation patterns, especially in terms of who the outsiders are. The findings show the need to examine various aspects of labour precariousness in order to capture the complexity of post-industrialised labour markets and identify different types of outsiders across Europe that need to be protected for building a more cohesive society.
Mind the gap: technology, millennial leadership and the cross-generational workforce

It comes as no surprise that different generations respond to and utilise emerging technology in vastly different ways. However as more Millennials take on leadership positions within academic libraries, their attitudes towards and uses of technology may bring conflicting expectations for leadership to the forefront. What are the generational traits and motivations of the Millennial and how will they manifest themselves as a style of leadership? What are some areas of tension arising from Millennial leadership and technology utilisation, and what steps can the Millennial leader take to alleviate such tension? Written by a Millennial who became a Dean of University Libraries at the age of 29, this article explores the challenges faced by the Millennial leader and the inherent opportunities for growth at both the personal and the organisational levels.
VX765, a Specific Caspase-1 Inhibitor, Alleviates Lung Ischemia Reperfusion Injury by Suppressing Endothelial Pyroptosis and Barrier Dysfunction

Lung ischemia reperfusion injury (LIRI) is a complex pathophysiological process with high morbidity and mortality. An important pathophysiological characteristic of LIRI is endothelial barrier dysfunction, although the mechanism involved in this process remains unclear. VX765, a specific caspase-1 inhibitor, has been shown to have a protective effect against several diseases including sepsis, atherosclerosis, and glial inflammatory disease. The objective of this study was to determine whether VX765 had a protective effect in LIRI. The results showed that lung ischemia/reperfusion (I/R) and oxygen/glucose deprivation and reoxygenation (OGD/R) induced endothelial pyroptosis and barrier dysfunction characterized by an inflammatory response. Treatment with VX765 successfully alleviated I/R- and OGD/R-induced endothelial pyroptosis and barrier dysfunction by inhibiting caspase-1 in vivo and in vitro. In conclusion, these findings showed that VX765 provided effective protection against lung I/R-induced endothelial pyroptosis and barrier dysfunction.
A PROCEDURE FOR QUANTITATIVE KINEMATIC ANALYSIS IN RUNNING ON TREADMILL

The purpose of this paper is to describe and test a method and a special developed software package capable of doing a complete 3-D kinematic analysis in treadmill running, including the assessment of kinematic asymmetries by a simultaneous right and left analysis. A pilot study using 8 recreational runners demonstrated that accurate and repeatable quantitative data can be collected and analyzed with the procedure. Comparison of specific kinematic data with literature studies revealed same significant difference in total joint range of motion. Some measurements and samples plots are also presented and discussed. The method and the user friendly software presented here seems to be an useful tool for scientists, trainers and athletes to assess and evaluate biomechanical data during running.
Assessment of Human Mycotoxin Exposure in Hungary by Urinary Biomarker Determination and the Uncertainties of the Exposure Calculation: A Case Study

Urinary biomarkers of mycotoxin exposure were evaluated in the case of healthy people (n = 41) and coeliac patients (n = 19) by using a multi-biomarker LC-MS/MS immunoaffinity based method capable to analyse biomarkers of nine mycotoxins, i.e., fumonisin B1 (FB1), fumonisin B2 (FB2), deoxynivalenol (DON), zearalenone (ZEN), ochratoxin A (OTA), Aflatoxin B1 (AFB1), T-2 toxin, HT-2 toxin and Nivalenol (NIV). Urinary biomarker concentrations were used to calculate the probable daily intake (PDI) of fumonisin B1, deoxynivalenol, zearalenone and ochratoxin A and compared with their tolerable daily intake (TDI). The human urinary excretion rate values reported in the literature and the 24 h excretion rate measured in piglets were used to estimate and compare the PDI values of the four mycotoxins. The highest mean biomarker concentrations were found for DON (2.30 ng/mL for healthy people and 2.68 ng/mL for coeliac patients). Mean OTA concentration was significantly higher (p < 0.001) in healthy people compared to coeliac patients. PDI calculated with piglets excretion data exceeded the TDI values by a much smaller percentage than when they were calculated from human data, especially for FB1. The uncertainties arising from the different calculations can be well perceived on the basis of these data.
Fe3+/FeT ratios of amphiboles determined by high spatial resolution single-crystal synchrotron Mössbauer spectroscopy

Abstract The Fe3+/FeT ratios (Fe3+/[Fe2++Fe3+]) in minerals can be used to understand their crystallization and post-crystallization conditions. However, as natural minerals are often zoned and contain inclusions, bulk techniques, e.g., wet chemistry, may not provide accurate Fe3+/FeT values for a single phase of interest. We determined Fe3+/FeT ratios of amphiboles in different crystallographic orientations by single-crystal synchrotron Mössbauer spectroscopy (SMS) in energy and time domain modes from four volcanic localities (Long Valley Caldera, Mount St. Helens, Lassen Volcanic Center, U.S.A., and Mt. Pinatubo, Philippines). The high spatial resolution (as low as 12 × 12 μm spot size) and standard-free nature of SMS allow the detection of intra-grain compositional heterogeneities in Fe3+/FeT with relatively low uncertainties. We combine SMS with major element compositions, water contents, and hydrogen isotope compositions to document the Fe3+/FeT ratios as a function of mineral composition and post-crystallization dehydrogenation. Spectra were fitted with up to five distinct sites: ferrous iron on M(1), M(2), M(3), and ferric iron on M(2) and M(3), consistent with X‑ray diffraction studies on single crystals of amphibole. The Fe3+/FeT ratios range from 0.14 ± 0.03 (Long Valley Caldera), 0.51 to 0.63 ± 0.02 (representing intra-grain heterogeneities, Mount St. Helens) to 0.86 ± 0.03 (Lassen Volcanic Center). The latter grain experienced post-crystallization dehydrogenation, shown by its low water content (0.6 ± 0.05 wt%) and its elevated hydrogen isotope composition (δD = +25 ± 3‰ relative to SMOW). The Fe3+/FeT ratios of 0.62 ± 0.01 and 0.20 ± 0.01 of two Mt. Pinatubo grains correlate with high-Al2O3 cores and low-Al2O3 rims and smaller phenocrysts in the sample, respectively. This study shows that SMS is capable of distinguishing two different domains with dissimilar Fe3+/FeT values formed under different crystallization conditions, demonstrating that SMS in combination with major element, water, and hydrogen isotope compositions allows the interpretation of amphibole Fe3+/FeT ratios in the context of crystallization and post-crystallization processes.
Dynamics of a Laser-Induced Bubble above the Flat Top of a Solid Cylinder—Mushroom-Shaped Bubbles and the Fast Jet

The dynamics of a laser-induced bubble on top of a solid cylinder is studied both experimentally and numerically. When the bubble is generated close to the flat top along the axis of the cylinder and its maximum radius exceeds the one of the flat top surface, it collapses in the form of a mushroom with a footing on the cylinder, a long stem and a hat-like cap typical for a mushroom head. The head may collapse forming a thin, fast liquid jet into the stem, depending on bubble size and bubble distance to the top of the cylinder. Several experimental and numerical examples are given. The results represent a contribution to understand the behavior of bubbles collapsing close to structured surfaces and in particular, how thin, fast jets are generated.
Terminal heterocyst differentiation in the Anabaena patA mutant as a result of post-transcriptional modifications and molecular leakage

The Anabaena genus is a model organism of filamentous cyanobacteria whose vegetative cells can differentiate under nitrogen-limited conditions into a type of cell called heterocyst. These heterocysts lose the possibility to divide and are necessary for the colony because they can fix and share environmental nitrogen. In order to distribute the nitrogen efficiently, heterocysts are arranged to form a quasi-regular pattern whose features are maintained as the filament grows. Recent efforts have allowed advances in the understanding of the interactions and genetic mechanisms underlying this dynamic pattern. However, the main role of the patA and hetF genes are yet to be clarified; in particular, the patA mutant forms heterocysts almost exclusively in the terminal cells of the filament. In this work, we investigate the function of these genes and provide a theoretical model that explains how they interact within the broader genetic network, reproducing their knock-out phenotypes in several genetic backgrounds, including a nearly uniform concentration of HetR along the filament for the patA mutant. Our results suggest a role of hetF and patA in a post-transcriptional modification of HetR which is essential for its regulatory function. In addition, the existence of molecular leakage out of the filament in its boundary cells is enough to explain the preferential appearance of terminal heterocysts, without any need for a distinct regulatory pathway. Author summary Understanding multicellular pattern formation is key for the study of both natural and synthetic developmental processes. Arguably one of the simplest model systems for this is the filamentous cyanobacterium Anabaena, that in conditions of nitrogen deprivation undergoes a dynamical differentiation process that differentiates roughly one in every ten cells into nitrogen-fixing heterocysts, in a quasi-regular pattern that is maintained as the filament keeps growing. One of the most characteristic mutations affecting this process forms heterocysts mostly constrained to the terminal cells of the filament. We have used experimental observations to propose a mathematical model of heterocyst differentiation able to reproduce this striking phenotype. The model extends our understanding of the regulations in this pattern-forming system and makes several predictions on molecular interactions. Importantly, a key aspect is the boundary condition at the filament’s ends: inhibitors of differentiation should be able to leak out of the filament, or otherwise the terminal cells would not differentiate. This highlights, in a very clear example, the importance of considering physical constraints in developmental processes.
E-Service Quality, E-Loyalty, and E-Satisfaction Muslim Travellers

This study aims to determine the effect of e-service quality on e- loyalty with e-satisfaction as an intervening variable for muslim travellers. The population are Traveloka users in Java. Purposive random sampling are used. The sample was obtained from 170 respondents by online collecting data questionnaire. SPSS 21.0 program are used to data analyze. The analytical tool were Multiple Regression and Path Analysis. The results showed that: e-service quality aspects of reliability, tangible, and empathy had a positive and significant effect on e-satisfaction. E- satisfaction and E-Service have a positive and significant impact on e- loyalty. E-satisfaction can mediate the impact of reliability, tangible, and empathy on e-loyalty, while responsiveness and assurance do not mediate the effect of e-satisfaction on e-loyalty The results of this study can theoretically strengthen the existing theory that e-satisfaction can mediate the effect of reliability, tangible and empathy on e-loyalty, while responsiveness and assurance do not mediate the impact of e-satisfaction on e-loyalty. The practical implications in this study are used as input for platform provider to improve the quality of services provided by platform provider to muslim travelers.
Retrograde capabilities of adeno-associated virus vectors in the central nervous system

Adeno-associated virus (AAV) vectors delivered at the axonal terminals can be retrogradely transported toward neuronal cell bodies throughout the axons. This retrograde phenomenon can serve as a powerful tool for experiments and gene therapy using AAVs. The advantages of using AAV vectors delivered retrogradely are greater cellular specificity, high transduction efficiency, increased safety, and absence of cytotoxicity. The numerous axonal projections in the nervous system provide a neuronal network for the convenient and widespread distribution of viral vectors between adjacent brain structures and over long distances. The retrograde efficiency of AAVs in the neurons of the central nervous system (CNS) depends on AAV serotype, the region of injection, and the type of neurons. In this review, we describe AAV serotypes and their retrograde transport properties after injection and discuss brain structures or types of cells that are targeted for retrograde transport. In particular, AAV serotypes 2, 5, 8, 9, rh10, and PHP.eB are extensively reviewed as they demonstrate retrograde transport potential suitable for use in gene therapy applications.
Ergonomic Risks in the Printing Company and Workers’ Wellbeing

The aim of the study was to analyze the ergonomic risks in the printing company and to study the impact of ergonomics risks on employees’ wellbeing. The study involved 67 company workers aged 18 to 67 years. In the study, physical load evaluation methods and questionnaire on welfare and psychoemotional risks at work, adopted by Swedish Environmental Research Institute, were used. It was proved that production workers were subjected to increased physical workload. At work they are exposed to physical pressure on hands, shoulders and back. The workload is more affected by the increase in work tension due to limited time of order execution. It was concluded that ergonomic risks partly affect employees’ wellbeing; however, uncertainty about the organization’s long-term plans and lack of understanding of employees’ contribution to performance of the organization are the most important reasons that affect the employees’ wellbeing.
Light activated semiconductors for ETC pulsed power applications

The integration of a capacitive pulsed power supply system into a combat fighting vehicle with ETC weaponization requires the development of compact PPS modules with a high reliability of their energy storage and pulse forming components. To fulfill these requirements a variety of switch technologies have been investigated for many years. This paper gives first results of the investigations on a new type of a semiconducting switch which is activated directly by an optical trigger input. The attractiveness of this switch is its lower trigger power requirement, its compact set-up, and its high reliability. Integrated breakdown diodes prevent the switch from a damage in case of a malfunction of the trigger system of one wafer. A high voltage set-up of this switch technology was tested under ETC conditions. The paper presents the test set-up as well as the results obtained from the experiments. In the conclusion of the paper, the impacts of this switch technology on the development of future ETC gun PPS modules is discussed.
The Place of Nipple-Sparing Mastectomy in the Treatment of Breast Cancer: Review of the Literature

Introduction: Mastectomy with conservation of the nipple-areola complex (NAC) in breast cancer care has been controversial with regards to the oncological safety of this procedure and the risk of complications including NAC necrosis. Aim: The objective of this study is to assess, through a literature review, the safety and reliability of a conservative NAC mastectomy in breast cancer treatment, paying attention to the rate of local recurrence and complications. Methods: A review of the literature was conducted from PubMed data, and articles published between January 2007 and December 2017, using the terms “nipple-sparing mastectomy”, “breast cancer”, “local recurrence”, “necrosis of the nipple”, “global complications”. The articles were analyzed with regards to the following parameters of evaluation: local recurrence, recurrence rate at NAC level, global complication rates and nipple necrosis rates. Results: In the 36 studies we selected, the average rate of local recurrence was 3.23%. The average rate of recurrence at the NAC was 0.81%. The average rate of complications was 20%. The average rate of necrosis of the NAC was 5.9%. The main factors of these recurrences were the tumor size > 5 cm and tumor stage > stage II. Conclusion: Conservative mastectomy of the nipple-areola complex offers an aesthetic advantage and oncological safety in carefully selected patients with breast cancer.
An Insight into the Abiotic Stress Responses of Cultivated Beets (Beta vulgaris L.)

Cultivated beets (sugar beets, fodder beets, leaf beets, and garden beets) belonging to the species Beta vulgaris L. are important sources for many products such as sugar, bioethanol, animal feed, human nutrition, pulp residue, pectin extract, and molasses. Beta maritima L. (sea beet or wild beet) is a halophytic wild ancestor of all cultivated beets. With a requirement of less water and having shorter growth period than sugarcane, cultivated beets are preferentially spreading from temperate regions to subtropical countries. The beet cultivars display tolerance to several abiotic stresses such as salt, drought, cold, heat, and heavy metals. However, many environmental factors adversely influence growth, yield, and quality of beets. Hence, selection of stress-tolerant beet varieties and knowledge on the response mechanisms of beet cultivars to different abiotic stress factors are most required. The present review discusses morpho-physiological, biochemical, and molecular responses of cultivated beets (B. vulgaris L.) to different abiotic stresses including alkaline, cold, heat, heavy metals, and UV radiation. Additionally, we describe the beet genes reported for their involvement in response to these stress conditions.
How international marketers make decisions: exploring approaches to learning and using heuristics

PurposeThe paper addresses the following research question: how do decision-makers use heuristics in their international business (IB) environment? Whereas, the literature has focused on entrepreneurial companies, here contrasting approaches to learning and using heuristics in international marketing (IM) decisions are examined and discussed.Design/methodology/approachThe paper aims to address a gap in the study of micro-foundations of internationalization, exploiting research from other disciplinary fields. It combines a multidisciplinary literature review and longitudinal case studies to illustrate different approaches in learning and using heuristics by international marketers.FindingsInternational marketers can adopt “closed” heuristics that are consolidated and consistently followed, or “open” heuristics, which are constantly being adapted and learned. Established multinationals learn heuristics in international marketing decision-making, following both “closed” and “open” models.Originality/valueThis paper offers an original contribution by presenting different approaches not yet examined in the literature, focusing on how international marketers make decisions through learning and using heuristic rules. The focus is on established exporters, in contrast to the literature that has largely paid attention to the effectiveness of heuristics in new entrepreneurial firms.
THE EFFECTS OF LATERAL FRONT FORK FLEXIBILITY ON THE VIBRATIONAL MODES OF STRAIGHT-RUNNING SINGLE-TRACK VEHICLES

SUMMARY By means of a mathematical model the effects of lateral front fork flexibility on the vibrational modes of single-track vehicles have been studied. The analysis performed by Sharp has been used as a starting point. The results have been compared with Roe's empirical findings. The results of the analysis have been translated into practical advice for a more optimal front fork construction.