Miracle-dz/UniFAR-FTUs huggingface dataset:
PATHOGENICITY OF FUSARIUM VERTICILLOIDES ON MAIZE RELATED TO DETECTABLE FUMONISIN B1

Aggressiveness of 10 Fusarium verticilloides isolates originated from naturally infected maize grains were studied towards susceptible cultivar ,Three Way Cross(TWC-310) seedling. Isolates differentiation has been done based on pathogenicity parameters as: a percentage of non-emerged seedlings, survival plants, plant vigour and disease severity. All tested isolates expressed various degrees of pathogenic capabilities as slightly, moderately and highly virulent. Percentage of survival plants and vigour were reduced, while disease severity ratio increased from 2.7 51.6%. Fumonisin production can play a role not only in plant pathogenicity but also in pathogen aggressiveness. The study suggested to correlate between the ability of examined isolates to produce that mycotoxin in vitro with their phytotoxicity behaviour. Isolates have been screened if some or all can synthesize fumonisin B1, whereas relatively different levels were detectable ranging from (400-1.680 μg/ mL). So, positive relationship between the aggressiveness of tested Fusarium isolates and their ability to produce this metabolite in vitro.
Customer Satisfaction on e-SERVQUAL in Islamic Online Banking Services

The recent development in the e-commerce services has shown a variety of established companies participating in the web business environment including Islamic banks. Business with the most experience and success in using e-commerce are beginning to realize that the indicator of success or failure of the e-commerce environment was included in the online services. Nowadays, the trend of a business is to serve the customer with best quality of services to enhance the consumer satisfaction and compete with the global competitors as online services enabled registered user to make products purchase transaction only through website such as check and manage financial standing, transfer funds, bill payment, prepaid reload and so forth. However, in recent times, Islamic banking users faced problems with the online system such as cannot log in to the system, payment failure and mostly security and privacy hindrance. Therefore, this study aimed to investigate the relationship between electronic service quality (e-SERVQUAL) and customer satisfaction towards Islamic Online Banking Services users. Based on the sample size, only 76 respondents were selected to participate in this study by using a convenience sampling. Further, Pearson correlation and multiple regression were reported to analyze the mentioned relationship. The findings have shown that there is a positive relationship between e-SERVQUAL and customer satisfaction in using Islamic online banking services. Based on the findings, Islamic online banking developer is recommended to improve more on their responsiveness in order to provide quick response to their customer’s requirements. Moreover, they also should be more reliable in providing accurate information in performing the promised services. They must assure that all of their customers can quickly get responds and true feedback regarding their problems to ensure customer satisfy with service provided. Besides, the safety of the website and the protection of customer information also considered a vital action that should be concerned in order to increase the customers’ satisfaction.
Decreased Risk of Coronavirus Disease 2019–Related Hospitalization Associated With the Omicron Variant of Severe Acute Respiratory Syndrome Coronavirus 2

Abstract Among 134 223 patients with coronavirus disease 2019 (COVID-19), we assessed how risk of hospitalization changed at different intervals in the pandemic, controlling for prior COVID-19 immunity. In multivariable analysis, outpatients with COVID-19 during the Omicron-predominant time period had significantly lower odds of hospitalization compared to pre-Delta (adjusted odds ratio, 0.26 [95% confidence interval, .22–.32]).
Underreporting of accidents with cutting and piercing objects in nursing

This study aimed at: identifying occupational accidents caused by percutaneous injuries among nursing workers, identifying whether or not accidents were reported and at learning about the reason for non-reporting. It is a descriptive study with a quantitative analysis of the data collected through the interview technique applied to 394 nursing workers from two hospitals in Sao Paulo State. The results showed that 30% of the 394 workers had an accident in 2001 and of such accidents, 277 (70.30%) were caused by percutaneous injuries, 173 (62.45%) accidents were reported and 104 (37.55%) were not reported. The reasons leading to non-reporting were related to beliefs, lack of knowledge and information concerning contamination risks and to the form of data recording.
Chapter 10: Compositions Created with Constraint Programming Torsten Anders

: This chapter surveys music constraint programming systems, and how composers have used them. The chapter motivates and explains how users of such systems describe intended musical results with constraints. This approach to algorithmic composition is similar to the way declarative and modular compositional rules have successfully been used in music theory for centuries as a device to describe composition techniques. In a systematic overview, this survey highlights the respective strengths of different approaches and systems from a composer's point of view, complementing other more technical surveys of this field. This text describes the music constraint systems PMC, Score-PMC, PWMC (and its successor Cluster Engine), Strasheela and Orchidée -- most are libraries of the composition systems PWGL or OpenMusic. These systems are shown in action by discussing the composition process of specific works by Jacopo Baboni-Schilingi, Magnus Lindberg, Örjan Sandred, Torsten Anders, Johannes Kretz and Jonathan Harvey.
Emotional Loneliness, Suicidal Ideation, and Alexithymia in Adolescents Who Commit Child-to-Parent Violence

The objective of this research was to explore the relationship between involvement in child-to-parent violence (CPV) and the development of emotional loneliness, suicidal ideation, and alexithymia based on sex; 1,928 adolescents of both sexes participated (50.5% males and 49.5% females), aged between 12 and 18 years (M = 14. 67, SD = 1.77), enrolled in four educational centers in Spain. A multivariate analysis of variance (3 × 2 MANOVA) was applied using sex and CPV levels as independent variables. Univariate analyses were carried out to explore the significant relationships detected. Results showed that the adolescents with higher CPV scored higher in emotional loneliness, suicidal ideation, and alexithymia. Girls showed a greater prevalence of CPV at the medium and high levels. An interaction of sex and CPV with alexithymia was detected. Girls with high and moderate values of CPV presented a higher level of alexithymia. These results provide novel information in the field of CPV. Previous research has placed the main focus of analysis on the adolescents’ behavior problems and not so much on their perceptions of personal adjustment and their emotional experiences. The information presented in this study contributes to achieve a more precise definition of the profile of adolescent who assault their parents for better prevention of CPV.
Historical contingencies and phage induction diversify bacterioplankton communities at the microscale

Significance The microbial decomposition of organic matter is a critical component of the global biogeochemical cycle that emerges from cellular interactions on microscale resource patches. The ecological processes controlling community dynamics in these microenvironments remain poorly understood. We show, through metagenomics, metabolomics, and modeling, that complex marine microbial communities growing on microscale resource particles diverge both taxonomically and functionally due to stochastic colonization, historical contingencies, and growth processes affected by community contexts. Prophage induction, especially among keystone organisms, is one significant contributor to covariation in community composition, species diversity, and biomass. Our results suggest that variability in microscale community assembly promotes coexistence among diverse metapopulations and that divergence in microscale functional states may translate to large-scale variation in particle degradation rates.
Development of Probabilistic Risk Assessment Methodology of Decay Heat Removal Function Against Combination Hazard of Low Temperature and Snow for Sodium-Cooled Fast Reactors

A probabilistic risk assessment (PRA) should be performed not only for earthquake and tsunami which are major natural events in Japan but also for other natural external hazards. However, PRA methodologies for other external hazards and their combination have not been sufficiently developed. This study is aimed at developing a PRA methodology for the combination of low temperature and snow for a sodium-cooled fast reactor which uses the ambient air as its ultimate heat sink to remove decay heat under accident conditions. The annual exceedance probabilities of low temperature and of snow can be statistically estimated based on the meteorological records of temperature, snow depth and daily snowfall depth. To identify core damage sequence, an event tree was developed by considering the impact of low temperature and snow on decay heat removal systems (DHRSs), e.g., a clogged intake and/or outtake for a DHRS and for an emergency diesel generator, an unopenable door on necessary access routes due to accumulated snow, failure of intake filters due to accumulated snow, and possibility of water freezing in cooling circuits. Recovery actions (i.e., snow removal and filter replacement) to prevent loss of DHRS function were also considered in developing the event tree. Furthermore, considering that a dominant contributor to snow risk can be failure of snow removal around intakes and outtakes caused by loss of the access routes, this study has investigated effects of electric heaters installed around the intakes and outtakes as an additional countermeasure. By using the annual exceedance probabilities and failure probabilities, the event tree was quantified. The result showed that a dominant core damage sequence caused by a snow and low temperature combination hazard is the failure of the electric heaters and the loss of the access routes for snow removal due to low temperature and snowfall which last for a day, and daily snowfall depth of 2 m/day.
Relationship between the number of lymph nodes dissected and prognosis in muscle‐invasive bladder cancer in the era of neoadjuvant chemotherapy

Many studies have shown a good prognostic association with a large number of lymph node dissections. However, most of these studies did not include patients who have received neoadjuvant chemotherapy. The purpose of this study was to verify the relationship between survival outcomes and the number of lymph nodes removed during radical cystectomy in patients with muscle‐invasive bladder cancer in the era of neoadjuvant chemotherapy.
Parasitic plant small RNA analyses unveil parasite-specific signatures of microRNA retention, loss, and gain

Abstract Parasitism is a successful life strategy that has evolved independently in several families of vascular plants. The genera Cuscuta and Orobanche represent examples of the two profoundly different groups of parasites: one parasitizing host shoots and the other infecting host roots. In this study, we sequenced and described the overall repertoire of small RNAs from Cuscuta campestris and Orobanche aegyptiaca. We showed that C. campestris contains a number of novel microRNAs (miRNAs) in addition to a conspicuous retention of miRNAs that are typically lacking in other Solanales, while several typically conserved miRNAs seem to have become obsolete in the parasite. One new miRNA appears to be derived from a horizontal gene transfer event. The exploratory analysis of the miRNA population (exploratory due to the absence of a full genomic sequence for reference) from the root parasitic O. aegyptiaca also revealed a loss of a number of miRNAs compared to photosynthetic species from the same order. In summary, our study shows partly similar evolutionary signatures in the RNA silencing machinery in both parasites. Our data bear proof for the dynamism of this regulatory mechanism in parasitic plants.
LncRNA CASC9 activated by STAT3 promotes the invasion of breast cancer and the formation of lymphatic vessels by enhancing H3K27ac‐activated SOX4

Numerous long noncoding RNAs (lncRNAs) are abnormally expressed in breast cancer (BC), but the underlying mechanisms remain large unknown. Here, we aimed to investigate the functions and mechanisms of lncRNA cancer susceptibility candidate 9 (CASC9) in BC. Western blotting and quantitative real‐time PCR (qRT‐PCR) were performed to assess gene and protein expression, respectively. The proliferative and metastatic abilities of BC cells were tested by cell counting kit‐8 and transwell assays, respectively. The formation of lymphatic vessels was detected by tube formation assay. Chromatin immunoprecipitation (ChIP) and dual luciferase reporter assays were performed to verify molecular interactions. CASC9 was found to be highly expressed in BC tissues and cell lines, and ectopic overexpression was positively associated with tumor volume, TNM stage, and lymph node metastasis. In addition, CASC9 silencing significantly inhibited the proliferation and invasion of BC cells, as well as BC‐associated invasion and formation of lymphatic vessels of human dermal lymphatic endothelial cells. Mechanical studies demonstrated that CASC9 could be transcriptionally activated by STAT3 and elevate SOX4 expression by enhancing the acetylation of its promoter region. Our results illustrated that STAT3‐activated CASC9 served as a tumor‐promoting gene involved in promoting BC invasion and BC‐associated formation of lymphatic vessels by upregulating SOX4 through altering H3K27ac level. This finding elucidated a new underlying network of CASC9 in the metastasis of BC.
Analysis of stability law and optimization of slope angle during excavation of deep concave mine slope

Occasional collapse failure is a typical occurrence during mine slope excavation processes. This study aimed to investigate the disaster law in the process of mining slope excavation, and further explore the optimal selection of excavation angle. Based on the systematic analysis of the residual sliding force and deformation response characteristics during slope excavation, the increment of the residual sliding force increases and the stability coefficient decreases with the increase in excavation depth. Additionally, a numerical model of the Jinchuan mining area in Jinchuan City, Gansu Province, China was created using the Midas-GTS finite element software. The influence of different excavation slope angles on slope stability was analyzed via numerical simulation under certain step slope height and width. The results show that the force and deformation of the slope were unfavorable to slope stability, and the slope stability coefficient would decrease gradually with the increase in slope angle. In addition, the optimal excavation angle combination ranges were determined as 62°~ 65°, 64°~ 67°, 67°~ 69°, 70°~ 71°, 73°, 75°~ 76°, 77°~ 80°considering the stability and maximum recovery. Therefore, the above research results verify the loading effect of mine slope excavation, and can serve as a reference for studies on the optimal range of excavation angles for the mine slope.
Cooling‐activated dorsomedial hypothalamic BDNF neurons control cold defense in mice

BDNF and its expressing neurons in the brain critically control feeding and energy expenditure (EE) in both rodents and humans. However, whether BDNF neurons would function in thermoregulation during temperature challenges is unclear. Here, we show that BDNF neurons in the dorsomedial hypothalamus (DMHBDNF) of mice are activated by afferent cooling signals. These cooling‐activated BDNF neurons are mainly GABAergic. Activation of DMHBDNF neurons or the GABAergic subpopulations is sufficient to increase body temperature, EE, and physical activity. Conversely, blocking DMHBDNF neurons substantially impairs cold defense and reduces energy expenditure, physical activity, and UCP1 expression in BAT, which eventually results in bodyweight gain and glucose/insulin intolerance. Therefore, we identify a subset of DMHBDNF neurons as a novel type of cooling‐activated neurons to promote cold defense. Thus, we reveal a critical role of BDNF circuitry in thermoregulation, which deepens our understanding of BDNF in controlling energy homeostasis and obesity.
SleepFCN: A Fully Convolutional Deep Learning Framework for Sleep Stage Classification Using Single-Channel Electroencephalograms

Sleep is a vital process of our daily life as we roughly spend one-third of our lives asleep. In order to evaluate sleep quality and potential sleep disorders, sleep stage classification is a gold standard method. In this paper, we introduce a novel fully convolutional neural network architecture (SleepFCN) to classify sleep stages into five classes using single-channel electroencephalograms (EEGs). The framework of SleepFCN includes two major parts for feature extraction and temporal sequence encoding namely multi-scale feature extraction (MSFE) and residual dilated causal convolutions (ResDC), respectively. These are then followed by convolutional layers of 1-sized kernels instead of dense layers to build the fully convolutional neural network. Due to the imbalance in the distribution of sleep stages, we incorporate a weight corresponding to the number of samples of each class in our loss function. We evaluated the performance of SleepFCN using the Sleep-EDF and SHHS datasets. Our experimental results show that the proposed method outperforms state-of-the-art works in both classification correctness and learning speed.
Individual and community-level determinates of risky sexual behaviors among sexually active unmarried men: A multilevel analysis of 2016 Ethiopian Demographic and Health Survey

Background In Ethiopia, HIV/AIDS continues to be a major public health problem mostly due to the high prevalence of risky sexual behaviors. However, research on risky sexual behavior and its determinants among unmarried men (never married, widowed, and divorced) who are highly vulnerable to risky sexual behavior was limited. Therefore, this study aimed to assess the magnitude of risky sexual behavior and its determinants among non-married men using a nationally representative sample. Methods The analysis was done on 5680 sexually active unmarried men aged 15–59 years using data from the 2016 Ethiopia Demographic Health Survey (EDHS). The main outcome variable was risky sexual behavior which defined as having at least one of the following: multiple sexual partners; initiation of sex before the age of 18 years; inconsistent condom use in the last 12 months; alcohol consumption at last sex. Multivariable generalized linear mixed-effects regression was employed to identify variables associated with risky sexual behavior. Result The overall magnitude of risky sexual behavior was 26.9% (95% CI; 25.7, 28.0). Currently employed (AOR = 2.49, 95% CI = 1.64–3.77), history of HIV testing (AOR = 2.51, 95% C = 1.95–3.23), drinking alcohol almost every day (AOR = 5.49, 95 CI = 2.73–11.02), and using Internet daily (AOR = 1.99, 95% CI = 1.06–3.74) increase the odds of risky sexual behavior. Whereas, primary education (AOR = 0.44, 95% CI = 0.32–0.61), secondary education level (AOR = 0.46, 95% CI = 0.29–0.72) and a high proportion of community-level media exposure (AOR = 0.42, 95% CI = 0.12–0.75) decrease the odds of risky sexual behavior. Conclusion In general, a significant proportion of sexually active unmarried men in Ethiopia have practiced risky sexual behavior. An intervention should be designed which are against the factors found to increase the odds of risky sexual behavior to reduce the incidence of HIV and other sexually transmitted infections.
Electronic health record data use in the assessment of quality indicators for glucocorticoid osteoporosis screening in systemic lupus erythematosus

Objective To determine whether electronic health record (EHR) data components could be identified and used to assess bone health quality indicators in patients with systemic lupus erythematosus as a foundation for population health management. Methods We identified patients in our EHR system who had diagnosis codes for lupus from 2012 to 2017 and characterized them based on the frequency and dosage of prescribed glucocorticoid medications. The medical records of patients who received repeated high-dose glucocorticoid orders were further reviewed for osteoporosis, osteoporotic fractures, receipt of appropriate preventive screening, and orders for protective medications based on established quality indicators. Descriptive statistics were calculated to summarize results. Results We identified 617 patients with a lupus diagnosis; 414 received glucocorticoid prescriptions, 189 received chronic, high-dose; and 83 received chronic, low-dose prescription orders. Of those with chronic high-dose glucocorticoid prescriptions, 14% had an osteoporosis diagnosis, 3% had an osteoporotic fracture, 51% received a prescription for calcium/vitamin D, 43% had bone mineral density screening orders, 20% received a spine radiograph order, 29% had a documented T-score, 12% received a prescription for osteoporosis medication, and 6% had a documented osteoporosis screening. We were able to identify data elements in the EHR for all nine components of the osteoporosis management quality indicator. Conclusions It is possible to identify data in the EHR for all attributes of the quality indicator for osteoporosis in lupus patients who receive chronic high-dose glucocorticoids. However, missing data and need to extract data from text-based notes may make development of population management tools challenging.
Pre-harvest desiccation strategies of soybean culture: a scenario without paraquat

Abstract The objective of this study was to evaluate the use of diquat, glufosinate ammonium, saflufenacil and flumioxazim, positioned alone and/or combined, in the pre-harvest desiccation of soybean crops. For this purpose, a field experiment was conducted, with application of the treatments in the phenological stage R 7.2 of soybean. At 3 DAA, the herbicides diquat and their combinations with flumioxazin and ammonium glufosinate, at all doses, resulted in defoliation and desiccation percentages greater than 90%. At 5 DAA, only the flumioxazin and glufosinate ammonium treatments, alone, did not show indices for harvesting. At 10 DAA, only the control differed from the other treatments in relation to desiccation, demonstrating the need to apply desiccants to enable harvest. The results indicate that the combination of herbicides may represent an alternative to reduce doses and increase the efficacy of isolated products through synergism, in addition to operational gains.