Miracle-dz/UniFAR-FTUs huggingface dataset:
Postbiotics secreted by Lactobacillus sakei EIR/CM-1 isolated from cow milk microbiota, display antibacterial and antibiofilm activity against ruminant mastitis-causing pathogens

Abstract Mastitis is one of the most important and multi-factorial diseases affecting dairy cows. This study was conducted to evaluate the effect of postbiotics secreted by lactic acid bacteria on mastitis. Within this aim, a total of 10 raw milk samples of healthy dairy cows were processed for the isolation of microbiota-derived bacteria. Following the isolation protocol, 24 isolates showing phenotypic characters similar to Lactobacillus species on specific MRS agar were selected and screened for their antibacterial activity against important mastitis-causing pathogens using the agar well diffusion method. According to the screening of the isolates, only one strain was found effective against all tested pathogens and selected for further assays. The isolate that exhibited a remarkable inhibitory effect was then identified as Lactobacillus sakei by 16S rRNA sequence analysis. The minimum inhibitory concentration of the postbiotics secreted by L. sakei into the culture medium was defined between the range of 40–50 mg/L. The antibacterial activity was also determined to be an acid-dependent effect, and HPLC analysis confirmed the presence of lactic acid (21.42 mg/mL) as the most common acid in the postbiotics. Among the 37 fatty acids, only oleic acid, palmitic acid, and stearic acid were detected. In addition to its antibacterial activity, postbiotics significantly reduced the biofilm formation of pathogens following the co-incubation, pre-treatment, and eradication assays, confirmed by confocal-laser and scanning electron microscopy. In conclusion, postbiotics with antibacterial and antibiofilm activity against important mastitis-causing pathogens can be used as a promising and natural agent in the prevention of mastitis. HIGHLIGHTS Lactobacillus sakei EIR/CM-1 was isolated from Holstein cow’s milk microbiota. Postbiotics from the strain EIR/CM-1 displayed the highest antibacterial activity against ruminant mastitis-causing pathogens. Co-incubation with postbiotics at 5 mg/mL and above concentrations reduced the biofilm formation of ruminant mastitis-causing pathogens by more than 70%. Lactic acid was found to be the highest organic acid in postbiotics.
Inflation and leptogenesis in high-scale supersymmetry

No-scale supergravity provides a successful framework for Starobinsky-like inflation models. Two classes of models can be distinguished depending on the identification of the inflaton with the volume modulus, $T$ (C-models), or a matter-like field, $\phi$ (WZ-models). When supersymmetry is broken, the inflationary potential may be perturbed, placing restrictions on the form and scale of the supersymmetry breaking sector. We consider both types of inflationary models in the context of high-scale supersymmetry. We further distinguish between models in which the gravitino mass is below and above the inflationary scale. We examine the mass spectra of the inflationary sector. We also consider in detail mechanisms for leptogenesis for each model when a right-handed neutrino sector, used in the seesaw mechanism to generate neutrino masses, is employed. In the case of C-models, reheating occurs via inflaton decay to two Higgs bosons. However, there is a direct decay channel to the lightest right-handed neutrino which leads to non-thermal leptogenesis. In the case of WZ-models, in order to achieve reheating, we associate the matter-like inflaton with one of the right-handed sneutrinos whose decay to the lightest right handed neutrino simultaneously reheats the Universe and generates the baryon asymmetry through leptogenesis.
Precocious inventors: early patenting success and lifetime inventive performance

ABSTRACT Precocious inventors have a higher inventive productivity during their remaining career. Inventors who have their first patent either applied for extraordinarily fast or a first patent of especially high quality are regarded as precocious. This paper systematically includes individual and employer characteristics that can drive career productivity beside an early patenting success to reveal the true productivity effect of precociousness. We show that early patenting success reveals dimensions of inventive ability that are not captured in individual characteristics that are predetermined at the start of the career such as the school education level. The favourable work environment precocious inventors enjoyed also has a relatively low explanatory value for career productivity. Precocious inventors also do not benefit from cumulative advantage. Although also rival firms can use early patenting success as indicator for a high career productivity, early employers can retain a high share of their precocious inventors. We propose several reasons for this surprising phenomenon.
Learning to Answer by Learning to Ask: Getting the Best of GPT-2 and BERT Worlds

Automatic question generation aims at the generation of questions from a context, with the corresponding answers being sub-spans of the given passage. Whereas, most of the methods mostly rely on heuristic rules to generate questions, more recently also neural network approaches have been proposed. In this work, we propose a variant of the self-attention Transformer network architectures model to generate meaningful and diverse questions. To this end, we propose an easy to use model consisting of the conjunction of the Transformer decoder GPT-2 model with Transformer encoder BERT for the downstream task for question answering. The model is trained in an end-to-end fashion, where the language model is trained to produce a question-answer-aware input representation that facilitates to generate an answer focused question. Our result of neural question generation from text on the SQuAD 1.1 dataset suggests that our method can produce semantically correct and diverse questions. Additionally, we assessed the performance of our proposed method for the downstream task of question answering. The analysis shows that our proposed generation & answering collaboration framework relatively improves both tasks and is particularly powerful in the semi-supervised setup. The results further suggest a robust and comparably lean pipeline facilitating question generation in the small-data regime.
Suitability of Ground Water in Southwest Kirkuk for Human Consumptions

Groundwater is one of the important sources of providing the human with water for drinking and other purposes. In Iraq, most of the agricultural land far from surface water sources, which forced these farmers to use groundwater wells as a source to cover the needs of the water and uses for different household. Furthermore, in some areas of Iraq, the available surface water that is suitable for human consumption is insufficient. Hence, the ground water is the viable solution to provide drinking water.The aim of this study is to show the extent validity of the ground water for various human uses.Twenty wells were chosen at different location in the southwest of Kirkuk city. Physical and chemical tests were carried for each water samples which include nitrite- nitrogen, phosphate, total hardness as CaCo3, total dissolved solids, chloride, PH, and turbidity. The results were evaluated and compared accordingly with World Health Organization (WHO) specifications. The results showed that the ground water in the study areas not suitable for drinking because of the contamination with Nitrite – nitrogen, phosphate and high contents of total hardness and TDS
A Divergence Minimization Perspective on Imitation Learning Methods

In many settings, it is desirable to learn decision-making and control policies through learning or bootstrapping from expert demonstrations. The most common approaches under this Imitation Learning (IL) framework are Behavioural Cloning (BC), and Inverse Reinforcement Learning (IRL). Recent methods for IRL have demonstrated the capacity to learn effective policies with access to a very limited set of demonstrations, a scenario in which BC methods often fail. Unfortunately, due to multiple factors of variation, directly comparing these methods does not provide adequate intuition for understanding this difference in performance. In this work, we present a unified probabilistic perspective on IL algorithms based on divergence minimization. We present $f$-MAX, an $f$-divergence generalization of AIRL [Fu et al., 2018], a state-of-the-art IRL method. $f$-MAX enables us to relate prior IRL methods such as GAIL [Ho & Ermon, 2016] and AIRL [Fu et al., 2018], and understand their algorithmic properties. Through the lens of divergence minimization we tease apart the differences between BC and successful IRL approaches, and empirically evaluate these nuances on simulated high-dimensional continuous control domains. Our findings conclusively identify that IRL's state-marginal matching objective contributes most to its superior performance. Lastly, we apply our new understanding of IL methods to the problem of state-marginal matching, where we demonstrate that in simulated arm pushing environments we can teach agents a diverse range of behaviours using simply hand-specified state distributions and no reward functions or expert demonstrations. For datasets and reproducing results please refer to this https URL .
Ionic diffusion and proton transfer of MgCl2 and CaCl2 aqueous solutions: an ab initio study under electric field

ABSTRACT We report on a series of ab initio molecular dynamics simulations on MgCl and CaCl aqueous solutions subjected to the effect of static electric fields. The diffusion properties of the solvated cationic species have been investigated both in the low-to-moderate field regime and for intense field strengths, where correlated proton transfers between the water molecules take place. Albeit the Grotthuss-like motion of the protons H dramatically affects the standard relative mobility of monovalent cations such as Li, Na, and K [Phys Chem Chem Phys 2017;19:20420], here we demonstrate that the rule ‘the bigger the cation the higher its mobility’ is preserved for divalent cations – such as Mg and Ca – even when a sustained protonic current is established by the field action. Notwithstanding the presence of charged particles anticipates the field threshold of the molecular dissociation of water from 0.35 V/Å to 0.25 V/Å, such a shift does not depend on the nominal charge the cations hold. Protons flow more easily in the MgCl solution (=2.3 S/cm) rather than in the CaCl (=1.7 S/cm) electrolyte solution because of a twofold reason. Firstly, Ca, being larger than Mg, more strongly hampers the propagation of a charge defect of the same sign (i.e. H). Secondly, we demonstrate that the mobility of Ca is sizably higher than that of Mg. This way, by spanning more efficiently the aqueous environment, Ca further inhibits the proton transfers along the H-bonded network. Finally, the protonic conduction efficiency is inversely proportional both to the ionic radii and to the nominal charge of the cations present in solution.
Assessment of knowledge and practice of oxygen therapy among doctors and nurses: A survey from Ondo State, Southwest Nigeria

Oxygen is among the commonly used drugs in acute emergencies. Prescription and administration of oxygen in emergencies by healthcare providers are reported to be inappropriate in most settings. There is a huge gap in the knowledge of health-care providers on various aspects of oxygen therapy. The purpose of this study was to assess the knowledge and practice of oxygen therapy among doctors and nurses working in Ondo State, South-West Nigeria and see how it compares with standard practice with a view to improving the quality care in this regard. A descriptive cross-sectional study was employed. The data were collected electronically using the Monkey survey application from consenting doctors and nurses through a self-administered validated and structured questionnaire. The questionnaire included the professional characteristics, educational background, awareness and use of oxygen therapy guidelines, knowledge of oxygen, indication for acute oxygen, and oxygen delivery practices. Data were analyzed using descriptive statistics and association between variables explored with Chi-square test at P < 0.05. One hundred and seventy-six health workers participated in the study with mean age of 37.30 ± 8.88 years. One hundred and twelve (63.60%) of the respondents were doctors while 64 (36.40%) of the respondents were nurses. Sixty-eight (60.70%) of the doctors and 19 (29.70%) of nurses had a high level of knowledge of oxygen therapy (p<0.001). About half of both doctors and nurses had a poor practice level of oxygen therapy. The duration of oxygen administration (how long ago the respondent was involved in oxygen use and previous to formal training on oxygen therapy) were significantly associated with level of knowledge of oxygen therapy (p<0.001, 0.017). Results from this study suggest that the level of knowledge was high in about half of the respondents and about the same percentage had poor oxygen therapy practice in hospitals in Ondo State, South West Nigeria. Therefore, regular training of healthcare workers should be encouraged to update their knowledge and practice of oxygen therapy.
Freshwater migratory movements in a widely distributed New Zealand amphidromous fish Cheimarrichthys fosteri

ABSTRACT Amphidromous fishes engage in migration to overcome the spatial mismatch between adult and larval habitat. The torrentfish (Cheimarrichthys fosteri), an endemic New Zealand amphidromous fish and only member of the Family Cheimarrichthyidae, display distinct spatial sexual segregation, but the migration assumed to overcome this segregation for reproduction is undocumented. We investigated the instream distribution of torrentfish, gaining insight into how barriers to reproduction are overcome, and how sex shapes migratory choices for the individual. We surveyed torrentfish at two spatial scales, examining the effects of sex and sexual maturity on distribution. We found that female torrentfish engage in prolonged upstream migrations, up to 100 km inland, with male torrentfish migrating upstream to a lesser extent. Both sexes return downstream to spawn, with males returning at the onset of maturity, while females may return and migrate back upstream, potentially making multiple downstream spawning migrations. Juvenile upstream migration likely results in competitive release and access to resources, but sets up a conflict between reproduction and transport of larvae into the nursery habitat in a timely manner. Adult downstream migration in torrentfish resolves this conflict and is similar to documented downstream spawning migrations in catadromous species.
Forced coupling vibration analysis of FBAR based on two-dimensional equations associated with state-vector approach

In our previous work, a system of two-dimensional equations for piezoelectric thin-film acoustic wave resonators (FBAR) has been derived and then successfully applied on the free vibration analysis of a finite FBAR plate. In this paper, we analyzed the forced vibrations of FBAR with alternating voltage applied on its electrodes. The derived two dimensional equations were simplified based on straight-crested wave approximations and were rewritten into matrix formalism by state-vector approach. With the knowledge of matrix function, the state-vector equation was successfully solved. Results of admittance were obtained with the dependence on the driving frequency and the aspect ratio. The obtained figure was compared with the frequency spectra obtained in free vibration analysis. Different aspect ratios and quality factors were taken to study the effects of them on the admittance. It is shown that admittance is highly influenced by mode couplings. Thus the work in this paper will be important for the thorough understanding of the coupling vibration of FBAR and its optimization design.In our previous work, a system of two-dimensional equations for piezoelectric thin-film acoustic wave resonators (FBAR) has been derived and then successfully applied on the free vibration analysis of a finite FBAR plate. In this paper, we analyzed the forced vibrations of FBAR with alternating voltage applied on its electrodes. The derived two dimensional equations were simplified based on straight-crested wave approximations and were rewritten into matrix formalism by state-vector approach. With the knowledge of matrix function, the state-vector equation was successfully solved. Results of admittance were obtained with the dependence on the driving frequency and the aspect ratio. The obtained figure was compared with the frequency spectra obtained in free vibration analysis. Different aspect ratios and quality factors were taken to study the effects of them on the admittance. It is shown that admittance is highly influenced by mode couplings. Thus the work in this paper will be important for the thoroug.
ASPEK-ASPEK HUKUM PERLINDUNGAN KONSUMEN DALAM PENYELENGGARAAN PERGURUAN TINGGI SWASTA DI INDONESIA

Penelitian ini menganalisa aspek-aspek hukum perlindungan konsumen dalam penyelenggaraan perguruan tinggi swasta di Indonesia. Penelitian ini menggunakan metode penelitian hukum normatif dengan metode pendekatan perundang-undangan ( statue approach ) dan pendekatan konseptual ( conseptual approach ). Berdasarkan hasil penelitian dapat disimpulkan bahwa Pertama, kedudukan para pihak dan produk jasa dalam penyelenggaraan perguruan tinggi swasta dapat dikategorikan sebagai para pihak dan produk dalam Undang-Undang Perlindungan Konsumen. Kedua, Pola hubungan hukum para pihak dalam penyelenggaraan perguruan tinggi swasta yakni antara mahasiswa dengan perguruan tinggi swasta memiliki kesamaan dengan hubungan antara konsumen dan pelaku usaha. Dimana hubungan hukum tersebut berlandaskan pada peraturan perundang-undangan, perjanjian, informasi dan kesepakatan antara para pihak. Sehingga melahirkan hak, kewajiban, dan tanggung jawab yang harus dipenuhi oleh masing-masing pihak. Selanjutnya terkait pertanggungjawaban penyelenggara PTS terhadap kerugian yang diderita oleh mahasiswa dapat didasarkan pada adanya kesalahan berupa perbuatan melawan hukum berdasarkan Pasal 1365 KUHPerdata atau kelalaiannya berdasarkan Pasal 1366 KUHPerdata dan/atau disebabkan perbuatan orang-orang yang menjadi tanggungannya berdasarkan Pasal 1367 KUHPerdata; adanya implied warranty , terutama terkait dengan tingkat kualitas atau janji-janji mengenai jasa pendidikan yang ditawarkan perguruan tinggi swasta kepada mahasiswa, serta prinsip strict liability juga dapat dijadikan dasar menuntut apabila terdapat hubungan kausalitas antara cacatnya produk pendidikan (Ijazah) dengan kerugian mahasiswa. Dimana selain dibebankan untuk mengganti kerugian mahasiswa, penyelenggara perguruan tinggi swasta sebagai pelaku usaha juga dapat dikenakan sanksi administratif dan sanksi pidana berdasarkan pembuktian lebih lanjut mengenai adanya unsur kesalahan yang dilakukan oleh organ badan penyelenggara dan/atau pengelola perguruan tinggi swasta.
Psychological Capital, future-oriented coping, and the well-being of secondary school teachers in Germany

Abstract It is essential to understand how teachers cope with stress and how this affects their well-being as teachers work in very demanding environments. The study employed the transactional model of stress and coping as a theoretical framework to investigate the relationship between the Psychological Capital dimensions (self-efficacy, hope, resilience, and optimism), future-oriented coping (proactive and preventive coping), and work-related well-being (job satisfaction and work engagement). An online survey was completed by 213 secondary school teachers in Germany. Multiple hierarchical regression analyses indicated that optimism and self-efficacy were significant predictors of proactive coping, and hope predicted preventive coping. Optimism, hope, and resilience had a significant impact on job satisfaction. Furthermore, hope, optimism, and proactive coping significantly predicted work engagement. Proactive coping mediated the relationship between teachers’ self-efficacy and work engagement as well as between optimism and work engagement, whereas preventive coping was not a significant mediator. The results imply that developing the Psychological Capital dimensions and proactive coping through interventions can be a valuable avenue to increase teacher well-being.
COVID-19 and Kidney Involvement – A Systematic Review

Coronavirus disease 2019 (COVID-19) is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). It has resulted in an ongoing worldwide pandemic since it was first recognized in December 2019. The kidney is one of the organs most easily affected by COVID-19. The injury of the kidney by COVID-19 manifested as hematuria, proteinuria, serum creatinine fluctuations, and even acute kidney injury (AKI). Critically ill patients with COVID-19 are much more prone to suffer from AKI. Moreover, AKI is related to poor outcomes in the patients infected with SARS-CoV-2. Therefore, early detection and active prevention of kidney injury are very important. In this article, we reviewed the epidemiology, clinical characteristics, pathogenesis, pathological manifestations, treatment, and prognosis of kidney injury in patients with COVID-19. It is expected to provide valuable insights for disease prevention and control from the perspective of nephrologists.
The Relationship between Falling and Quality of Life for The Elderly over 65 : Using Korean community health survey

Purpose : Few studies have examined the relationship between elderly falls and quality of life (QOL) in a large general population. Furthermore, although many studies have investigated the relationships between socio-demographic factors and falls, relatively few studies have evaluated the associations of places and environments with QOL of fall. The purpose of the scheme was to identify the relationship between falls and QOL in a large sample of the elderly. Methods : This study used raw data from the 2013 Korean community health survey. A total of 228,781 people participated in the 2013 study among them 61.552 people were aged 65 or older. Authors also excluded 40 people whose QOL confirmation was unclear. Therefore, final analysis was conducted 61,512 senior citizens. The survey contained questions about the occurrence of falls, number of falls occurring per year, location of occurrence, and cause of falls. QOL was measured using the EQ-5D, an evaluation tool developed by the EuroQol group. Results : The results showed a statistically significantly lower QOL to little fear and full of fear as compared with no fear of falls (p<.05). The number of falls was statistically significantly lower in one, two, and three or more times, than in zero (i.e. no falls)(p<.05). In the falling environments, fall experience, but not related to lighting (p>.05), had a significant lower in QOL compared without the experience (p<.05). Conclusion : This study concluded that there is a strong connection between fall and QOL to the elderly, particularly regarding the number of occurrences, place, and environment. However, we found that an environment (e.g. the lack of lighting) might not affect QOL. It means that when the experts who make an effective tool or intervention may not need to consider indoor and outdoor darkness.