Miracle-dz/UniFAR-FTUs huggingface dataset:
Haemorrhagic Lupus: A Diagnosis Emergency, Report about 6 Cases

Introduction: Haemorrhagic manifestations rarely represent the mode of onset of lupus and are a therapeutical and diagnosis emergency. We report 6 cases of haemorrhagic manifestations disclosing lupus. Patients and methods: It’s about a retrospective, descriptive and multicentric study ranged from 1st January 2014 to 5th January 2019. Were included in the study all cases of lupic disease revealed by hemorrhagic disorders, recorded in 3 Internal Medicine Departments in Dakar: DalalJamm, Dantec, Pikine. The diagnosis of lupus was made on the basis of the 1997 modified classification criteria of ACR for SLE. Results: We gathered 6 cases of women affected by lupic disease. The mean age was 32 years old with extremes ranged from 17 to 56 years. According to haemorrhagic disorders, the diagnosis of lupus was automatically made in 5 of the cases and it took 6 to confirm the last one. Haemorrhagic features were ruled by purpura (3/6 cases) and nosebleeding associated with gumbleeding (2/6 cases), epistaxis and melena (1/6 case), hypermenorrhea (1/6 case), cerebral haematoma (1/6case). Cutaneous (5/6), articular (4/6), renal (2/6) and serous (2/6) disorders specially represented the other manifestations. Biological findings showed cytopenia with 3 cases of anaemia, 1 case of leucopenia and 6 cases of thrombopenia. The average of the platelet count was at 20,000 cells/mm 3 with extremes ranged from 1000 to 35,000 cells/mm 3 . Thrombocytopenia was related to autoimmune thrombocytopenic purpura in 3 cases, to Evans’ syndrome in 2 cases, to macrophage activation syndrome in 1 Immunological investigations found the presence of antinuclear antibodies anti-dsDNA and anti-Sm All received bolus administration Prednisone at a of 1.5 mg/kg (3 cases) and 1 mg/kg to the other patients. A transfusion of platelet concentrates was performed for all of them. The evolution was favorable in 4 cases. Two patients died according to a septic and haemorrhagic shock. Conclusion: We report 6 cases of haemorrhagic manifestations disclosing lupus. Cutaneo-mucous location was more frequent and was related to moderate to severe thrombocytopenia with the presence of anti-Sm antibodies.
AIN on silicon based surface acoustic wave resonators operating at 5 GHz

The fabrication and characterisation of surface acoustic wave resonators operating in the gigahertz frequency range are presented. The devices were fabricated on thin AlN layers deposited by magnetron sputtering on high resistivity (100) oriented silicon substrates. Using direct writing e-beam lithography, well defined interdigital transducers with 300 nm finger width and spacing have been obtained. On-wafer microwave measurements have demonstrated a narrow bandstop frequency characteristic with high rejection at approximately 5 GHz and an electromechanical coupling coefficient of 0.53 .
How modal noise in multimode fibers depends on source spectrum and fiber dispersion

The speckle contrast for multimode fibers, and thus the modal noise, is essentially given by the impulse response of the fiber and the power spectrum of the source. Theoretical and experimental results show that laser sources with a large spectrum of narrow longitudinal modes may cause high speckle contrast and important modal noise over more than 1-km length in graded-index multimode fibers.
Successful Treatment of Nannizziopsis guarroi Infection Using Systemic Terbinafine in a Central Bearded Dragon (Pogona vitticeps)

Abstract Nannizziopsis guarroi infection in lizards presents therapeutic challenges, with reports of poor clinical outcomes, including antifungal toxicity, incomplete clearance of infection, and recrudescence of infection being common. The case presented here describes the successful treatment of an N. guarroi infection using systemic terbinafine and environmental disinfection in a captive-bred central bearded dragon (Pogona vitticeps). The lizard presented with darkly colored cutaneous lesions, and mycologic culture samples were identified as N. guarroi using matrix-assisted laser desorption/ionization–time of flight. Based upon the lack of clinical resolution of cutaneous lesions, weight loss, and reduced appetite, initial treatment with voriconazole was discontinued. Terbinafine was prescribed, and weekly environmental disinfection with sodium hypochlorite was initiated until cutaneous clearance of the fungus was confirmed by negative culture, histopathology, and N. guarroi quantitative polymerase chain reaction from cutaneous swab. Terbinafine treatment was discontinued after 80 days. There were no clinical signs of toxicity associated with the prolonged treatment, and the lizard has not developed any cutaneous lesions or illness in more than 2 yr of clinical follow-up. Although the ideal treatment of N. guarroi is still being investigated, this case demonstrates a promising and safe treatment option for an increasingly common and devastating disease.
Proposed Hybrid CorrelationFeatureSelectionForestPanalizedAttribute Approach to advance IDSs

NetworkIntrusionDetectionSystem(NIDS), widely used network infrastructure. Although many datamining has been used to increase the effectiveness of IDSs, current ID still struggle to perform well. therfore; proposed a new NIDS focused on feature_selection. The proposed CorrelationFeatureSelection_ForestPanalizedAttributes(CFS_FPA) used for dimensionality_reduction and selects the optimal_subset. based on two steps: first check each feature with a target(class) and choose only features that most effective by applying CFS filter using a statistical_method, then applied FPA to select only features will enhance ID and reduce_dimensionality. proposal tested with the NSLKDD experimental results of accuracy 0.997% and 0.004 FAR, wherein UNSWNB15_dataset accuracy and FAR are 0.995%, 0.008 consequently.
Photonic crystal slow light devices in silicon

Photonic crystals offer strong confinement of light, as well as control over the group velocity. We compare the resulting enhancement to that available in cavities and show that the group velocity can be controlled over a large spectral range, thus giving access to nonlinear functions. We show how coupled cavities allow tuning of the slowdown factor and present a very compact (5 μm long) optical switch based on slow light concepts.
“The Paper Is White”: Examining Diversity Issues With the Next Generation of Journalists

Although the lack of diversity in newsrooms and reporting remains a serious issue in the journalism industry, college journalism education and student media provide a critical opportunity for change. Yet prior research has found notable diversity gaps in both. This study analyzed the state of diversity at a Midwestern university student newspaper and found significant gaps in coverage of diverse populations. The findings suggest the need for more comprehensive diversity education within the college classroom and campus media advising. This is important not only for more representative student media, but also for the future of journalism.
Optoelectronic system integration on silicon: waveguides, photodetectors, and VLSI CMOS circuits on one chip

Optical waveguides, photodetectors, and VLSI CMOS circuits are integrated monolithically in different ways: in a combined integration technique the light-guiding film is deposited and covered with a SiO/sub 2/ layer replacing standard PSG as the dielectric insulation of polysilicon and metallization. In a stacked method the waveguide fabrication starts after metallization and test of the CMOS circuits. Electrooptical coupling is performed by butt-, leaky wave-, or, mirror-coupling of waveguides and photodetectors. To fabricate the system, SWAMI LOCOS technique is applied for monolithic integration of both, integrated optical devices, and microelectronic circuits. This paper discusses the integration technology and the results of static and dynamic measurements. >
Development of an Add-on 23Na-MRI Radiofrequency Platform for a 1H-MRI System Using a Crossband Repeater: Proof-of-concept

23Na-MRI provides information on Na+ content, and its application in the medical field has been highly anticipated. However, for existing clinical 1H-MRI systems, its implementation requires an additional broadband RF transmitter, dedicated transceivers, and RF coils for Na+ imaging. However, a standard medical MRI system cannot often be modified to perform 23Na imaging. We have developed an add-on crossband RF repeater system that enables 23Na-MRI simply by inserting it into the magnet bore of an existing 1H MRI. The three axis gradient fields controlled by the 1H-MRI system were directly used for 23Na imaging without any deformation. A crossband repeater is a common technique used for amateur radio. This concept was proven by a saline solution phantom and in vivo mouse experiments. This add-on RF platform is applicable to medical 1H MRI systems and can enhance the application of 23Na-MRI in clinical usage.
Shock experiments on basalt—Ferric sulfate mixes and their possible relevance to the sulfide bleb clusters in large impact melts in shergottites

Large impact‐melt pockets in shergottites contain both Martian regolith components and sulfide/sulfite bleb clusters that yield high sulfur concentrations locally compared to bulk shergottites. The regolith may be the source of excess sulfur in the shergottite melt pockets. To explore whether shock and release of secondary Fe‐sulfates trapped in host rock voids is a plausible mechanism to generate the shergottite sulfur bleb clusters, we carried out shock recovery experiments on an analog mixture of ferric sulfate and Columbia River basalt at peak pressures of 21 and 31 GPa. The recovered products from the 31 GPa experiment show mixtures of Fe‐sulfide and Fe‐sulfite blebs similar to the sulfur‐rich bleb clusters found in shergottite impact melts. The 21 GPa experiment did not yield such blebs. The collapse of porosity and local high‐strain shear heating in the 31 GPa experiment presumably created high‐temperature hotspots (~2000 °C) sufficient to reduce Fe3+ to Fe2+ and to decompose sulfate to sulfite, followed by concomitant reduction to sulfide during pressure release. Our results suggest that similar processes might have transpired during shock production of sulfur‐rich bleb clusters in shergottite impact melts. It is possible that very small CO presence in our experiments could have catalyzed the reduction process. We plan to repeat the experiments without CO.
How Much Value is Added by Value Added Models? An Analysis of Teachers’ Performance Over Time Using New York State Assessment Data

How Much Value is Added by Value Added Models by Mariana Ristea Adviser: Professor David Rindskopf There is a strong movement to evaluate teachers on the basis of students’ performance. To compare teachers fairly, as each may have a mixture of students with different abilities in a given subject area, one should account for variables reflective of students’ subject knowledge and background when entering a course. Most methods of control consist of highly sophisticated statistical models mostly difficult to explain to educators who are being evaluated using such methods. This research presents two value-added methods that could be replicated by using inhouse resources and standardized student assessment data which are either continuous or ordinal. One method is simpler to implement if one’s goal is to evaluate teachers’ performance based on students’ assessments scores reported as ordinal measures. The second method is similar to a more typical value-added approach and uses hierarchical linear structures to determine a classification of teachers’ performance based on their students’ assessment scores reported as continuous measures. Teachers’ “value-added” in a given academic year is typically calculated using students’ longitudinal New York State assessment data, reported in both ordinal and continuous forms. Comparison of results obtained from both methods, along with their interpretations, are used to examine trade-offs between accuracy of methods and their ease of use and transparency. The code used is included for practitioners who may wish to replicate this value-added methodology. Suggestions related to educational policy and feasibility of implementation of methods are also discussed.
The relationship between planned behavior family factors and intention to study abroad

This study explores the relationship between planned behaviour, i.e. attitude towards behaviour, subjective norm and perceived behavioural control and coherence towards intention to enrich the literature - Vietnamese students studying abroad at university. In addition, the study also explores the factors related to family cohesion to the intention of Vietnamese students to study abroad. This study was conducted through a cross-sectional survey using a targeted sampling technique (n=350). The SEM model was used to test the hypotheses. The SEM model proved that: The decisive factor affects the intention to study abroad with the coefficient of Regression Weight = 0.222. The subjective norm factor (norm) affects the intent variable with the coefficient of Regression Weight = 0.138; The behavioural intention control factor affects the intent factor with Regression Weights = 0.276; The factor through family cohesion (cohesion) affects the intent factor with Regression Weights = 0.159. The conclusions of this study provide valuable data for study abroad managers, universities, study abroad consulting service providers and families who want to invest in their children to study abroad.
Intraband and interband optical crosstalk in multiwavelength optical cross connects using tunable fiber Bragg gratings and optical circulators

Fiber Bragg grating (FBG) based wavelength division multiplexer (WDM) optical cross connect (OXC) is of great importance, which has the advantages of good performance and potential low cost. Optical crosstalk plays a major role in limiting practical implementations of an OXC. Crosstalk analyses presented so far generally focus on the traditional multiplexer/demultiplexer and optical switch based OXC architecture. In this paper, optical crosstalk in multiwavelength reconfigureable nonblocking OXCs using tunable FBGs and optical circulators (OCs) is discussed. Two crosstalk mechanisms, intraband and interband, are identified and analytical models are presented. Both first-order and second-order crosstalk contributions have been studied. For the intraband crosstalk, results show that the worst case coherent crosstalk is the dominant crosstalk, which is ~ 23 - 25 dB higher than the incoherent crosstalk, depending on the switching states of the 2 x 2 OXCs. For the interband crosstalk, results show that it is nonaccumulative and becomes very small with the increase of the number of fibers or the cascaded stages of 2 x 2 OXCs. However it deteriorates with the increase of the number of wavelengths per fiber.
Financial Performance and Human Development with Control of Regional Characteristics

Regional autonomy is a policy given by the central government to local governments. The granting of this right to autonomy will encourage the acceleration of economic development in the community. Local governments begin to regulate all affairs in their regions independently so that they will be faster in overcoming all existing problems, including problems of community welfare. The implementation of regional autonomy also gives full rights to regional governments, including in financial management in the regions. Effective, efficient, transparent and responsible financial management is an important basis for improving the community's welfare. Of course, increasing the financial performance of local governments will also increase the human development index. The performance of the local government needs to be assessed as a form of our supervision to the government. This government performance assessment can be measured through the ratio of regional independence, effectiveness and efficiency. In addition, proper management of existing resources in the area will be able to improve the welfare of the community. The purpose of this study is to empirically test the ratio of independence, effectiveness, efficiency to the human development index by controlling regional characteristics in the form of capital expenditures, operational expenditures, government size, regional original income, and population. The amount of data in this study were 29 districts and 6 cities in Central Java during 2015-2019. The results of this study state that the independence ratio, effectiveness ratio, and efficiency ratio can have a significant effect on the human development index. In addition, the control variables for regional characteristics in the form of capital expenditures, operational expenditures, government size, and population are able to influence the human development index. Meanwhile, local revenue has no effect on the human development index.
Fatigue Reliability Assessment of Deteriorated Bridges under Vehicle Dynamic Impacts

Environmental corrosion and vehicle dynamic impacts are among the major threats to the safety of existing bridges. The structural reliability is greatly endangered by their combined effects, which could possibly lead to a catastrophic failure. In this paper, the fatigue reliability of existing deteriorating steel bridges is evaluated. The dynamic stress ranges were obtained based on vehicle-bridge dynamic analysis. Varied material corrosion rates, vehicle types, vehicle speeds, and time-varied road surface conditions are considered. In the fatigue damage assessment approach, the bridge deteriorations of the road surface condition and structural components are included. At the end of each stress block, the fatigue life is estimated by evaluating the cumulative probability of failure. The effects of the corrosion induced area loss and moment of inertia reduction are limited and are much less than the random effects from road surface condition. Corrosion-induced fatigue strength reduction has a large effect on fatigue life. More than 60% reduction of fatigue life is predicted for different corrosion levels. The fatigue strength reduction is found more sensitive for the fatigue life estimation. Last, a new dynamic amplification factor for life-cycle bridge fatigue design (DALC) is proposed which is defined as the ratio of the life-cycle nominal live load stress range and the maximum static stress range. Fatigue damages from multiple stress range cycles due to each vehicle passage at varied vehicle speeds under various road conditions in bridge's life cycle and progressive deterioration are included.
Proteogenomic analysis of aneuploidy reveals divergent types of gene expression regulation across cellular pathways

How cells control gene expression is a fundamental question. The relative contribution of protein-level and transcript-level regulation to this process remains unclear. Here we perform a proteogenomic analysis of tumors and untransformed cells containing somatic copy number alterations (SCNAs). By revealing how cells regulate transcript and protein abundances of SCNA-containing genes, we provide insights into the rules of gene regulation. While gene compensation mainly occurs at the protein level across tumor types, genes gained or lost show surprisingly low protein compensation in lung and high RNA compensation in colon cancer. Protein complex genes have a strong protein-level regulation while non-complex genes have a strong transcript-level regulation. Exceptions are plasma membrane protein complexes showing a very low protein-level regulation. Strikingly, we find a strong negative association between the degree of transcript-level and protein-level regulation across genes and pathways. Moreover, genes participating in the same pathway show similar degree of transcript- and protein-level regulation. Pathways including translation, splicing and mitochondrial function show a stronger protein-level regulation while cell adhesion and migration pathways show a stronger transcript-level regulation. These results suggest that the evolution of gene regulation is shaped by functional constraints and that many cellular pathways tend to evolve a predominant mechanism of gene regulation, possibly due to energetic constraints. Highlights Proteogenomic analyses of cancer SCNAs reveal tissue specificity in gene compensation. Genes gained or lost show surprisingly low protein compensation in lung cancer and unexpected RNA compensation in colon cancer. We use DNA-RNA and RNA-protein correlations to infer the degree of RNA-level and protein-level regulation. Protein complex genes and non-complex genes show high protein-level and RNA-level regulation, respectively. Plasma membrane complexes are an exception showing more RNA-level than protein-level regulation than other complex genes. Genes participating in the same pathway show similar degree of RNA-level and protein-level regulation. There is a strong negative relationship between the RNA- and protein-level regulation among pathways, suggesting that they are regulated either at the protein or at the RNA level. Genes involved in RNA processing and protein synthesis are upregulated in highly aneuploid tumors, especially at the protein level.
Effect of educational interventions on knowledge of the disease and glycaemic control in patients with type 2 diabetes mellitus: a systematic review and meta-analysis of randomised controlled trials

Background Globally, type 2 diabetes has continued to increase, now accounting for over 90% of all diabetes cases. Though the magnitude of uncontrolled glycaemic levels in patients with type 2 diabetes is steadily rising, evidence showed that effectively controlled glycaemic levels can prevent complications and improve the quality of life of these patients. As little is known about the effect of educational interventions on this population, this systematic review and meta-analysis evaluated the effectiveness of educational interventions versus standard care on glycaemic control and disease knowledge among patients with type 2 diabetes. Methods PubMed, Google Scholar, Cochrane Library, Scopus, African Journals Online and Wiley Online Library were searched. Two authors independently assessed within-trial risk of bias in each included study using revised Cochrane risk-of-bias tool for randomised trials. A random-effects model was employed to estimate combined effect sizes. Subgroup analyses were employed to investigate possible sources of heterogeneity between studies. The overall certainty of the evidence was evaluated using the Grading of Recommendations Assessment, Development and Evaluation approach. Results A total of 19 trials with 2708 study participants were included in the review. Primary outcomes (glycaemic control) were reported in 18 trials. The pooled estimated impact of educational intervention on glycaemic levels using the random-effects model was −0.83 (95% CI: −1.17 to –0.49, p<0.001). Subgroup analyses revealed greater A1c reductions in those studies with intervention duration of up to 3 months and with empirical intervention designs. Educational interventions led to significant increases in participants’ knowledge of type 2 diabetes (standardised mean difference: 1.16; 95% CI: 0.71 to 1.60; I2=93%). Conclusion In the current review overall, educational interventions can potentially lead to improved glycaemic control levels in patients with type 2 diabetes despite heterogeneity across the studies. Besides, the findings showed that educational interventions could increase disease knowledge among patients with type 2 diabetes. PROSPERO registration number CRD42020205838.