Miracle-dz/UniFAR-FTUs huggingface dataset:
Conflicting Outcomes of Human Cytomegalovirus Infection Detected with Immunohistochemistry and Real-Time PCR in Korean Glioblastoma Patients

Background: Glioblastoma Multiforme (GBM) is the most frequent brain tumor with a median overall survival of less than 2 years. Several studies indicate that most of GBM tumors are associated with the Human Cytomegalovirus (HCMV). Based on HCMV infection of GBM in recent studies, experimental therapies including antiviral medication and immunotherapy are emerging. However, the presence of HCMV in GBM is still controversial because a minority of studies failed to identify the evidence of HCMV in GBM until recently. The aim of the study is to find the evidence of HCMV in Korean GMB tumors. Method: We collected 98 cases of GBM from 2004 to 2012. To detect the low level expression of HCMV antigen and gene in GBM tumors, we performed immunohistochemistry and real-time PCR. We used two antibodies, HCMV pp65 and HCMV EA, for immunohistochemistry. Eighteen cases containing sufficient tumor cells and showing moderate intensity in at least one of pp65 and EA immunohistochemistry were chosen to implement real-time PCR. Result: The HCMV pp65 antigen was detected in 73/90 (81.1%) and HCMV EA antigen was found in 46/90 (51.1%) of GBM cases. Seventeen cases (18.9%) showed moderate intensity for pp65 antigen and 12 cases (13.3%) showed moderate intensity for EA antigen. In contrary to positive immunohistochemical expressions, real-time PCR failed to detect HCMV UL55 gene in selected 18 glioblastoma specimens. Conclusion: HCMV antigens were immunohistochemically expressed in Korean GBM cases, which was not confirmed by real-time PCR. The evidence of HCMV infection in Korean GBM tumors was uncertain.
The Anatomy of a Web Archive Image Search Engine - Technical Report

This paper presents the research and development of a large-scale web image search engine, implemented as an added-value service to Arquivo.pt’s web archive. Users submit a text query and receive as result a list of related archived images and corresponding metadata. Supporting image search over web archives raises new challenges, namely having multiple versions of images and pages referenced by the same URLs over time. This raises problems that live-web search engines do not need to address: how to handle duplication of web-archived images over time and how to rank search results considering the temporal features. At the same time, the volume of temporal data to be processed is considerable, at over 8.5 billion files (2.4 billions images) crawled since 1992. Our approach to information extraction strikes the balance between coverage and efficient representation. This was achieved by storing only metadata that changed over time and by performing content based de-duplication, enabling finding duplicates indexed under different URLs. In addition, we developed a generic algorithm to image caption extraction from HTML pages created over the lifetime of the web. The main contributions of this paper are algorithms to identify relevant textual content in web pages that describe live-web and archived web images, a system architecture and workflow to index web-archived images and a ranking algorithm to order search results over web-archived images. This service is publicly available and fully open source; as of April 2021, it supports image search over 2.4 billion images crawled between 1992 and 2019.
NDT_A_288108 945..955

1Department of Preventive Intervention for Psychiatric Disorders, National Institute of Mental Health, National Center of Neurology and Psychiatry, Tokyo, Japan; 2Department of Neuropsychiatry, Kyorin University School of Medicine, Tokyo, Japan; 3Faculty of Rehabilitation, Niigata University of Health and Welfare, Niigata, Japan; 4Japan Medical Office, Takeda Pharmaceutical Company Limited, Tokyo, Japan; 5Medical Affairs, Lundbeck Japan KK, Tokyo, Japan; 6Medical Affairs Value Evidence, H. Lundbeck A/S, Valby, Denmark Background: Accumulating evidence suggests the presence of cognitive impairment in patients with major depressive disorder (MDD), which affects their psychosocial function and quality of life (QoL). PERFORM-J (Prospective Epidemiological Research on Functioning Outcomes Related to MDD in Japan) is an observational, multicenter study to assess longitudinal changes in depressive symptoms, psychomotor speed, subjective cognitive function, and psychosocial function. Methods: Five hundred and eighteen Japanese outpatients with MDD initiating new antidepressant monotherapy (first-line or switch from previous drug) as part of their routine medical care participated in this study. Assessments at baseline and over the 6-month observation period included physician-rated depression severity (Montgomery–Åsberg Depression Rating Scale), psychomotor speed (Digit Symbol Substitution Test; DSST), subjective cognition (Perceived Deficits Questionnaire–Depression), psychosocial function (Sheehan Disability Scale), and QoL (EuroQol-5 Dimension-5 Level). Results: Antidepressant treatment for 6 months improved depressive symptoms and subjective cognitive impairment (cognitive complaints), whereas psychomotor speed remained impaired (ie, DSST total score was >1 standard deviation below the norm) in 35.6% of patients at 6 months. Impairment of subjective cognition, but not psychomotor speed at month 2 was associated with poor psychosocial function and QoL at 6 months. There was a trend for higher relapse rates at 6 months in patients with greater subjective cognitive impairment at 2 months. Conclusion: These findings highlight the importance of evaluating cognitive difficulties to predict long-term outcomes in patients with MDD. Early intervention for cognitive complaints may decrease the relapse rate, which warrants further study.
Right-Tail Range Restriction: A Lurking Threat to Detecting Associations between Traits and Skill among Experts

It has been claimed by prominent authors that there is no relationship between differences in some human traits (e.g., cognitive ability, physical ability) and differences in skill among experts. We assert that the failure to detect such associations is often due to an extreme form of range restriction that particularly plagues research focused on expert samples: right-tail range restriction (RTRR). RTRR refers to a lack of representation of data from the far right segment of the normal distribution, inhibiting the observation of statistical associations. Using two example studies we demonstrate that, when RTRR is not present, relationships between differences in experts’ traits and differences in their degree of skill can be observed. Based on the characteristics of these studies we make recommendations for methodological practices that can be followed to help investigators overcome RTRR and facilitate the continued development of a robust and replicable science of expertise.
Stakeholders' Views on Integrated Reporting-Case Study in Vietnam

This study aims at exploring the stakeholders’ views on integrated reporting (IR), thereby providing an indication of the readiness of Vietnamese businesses to adopt IR. This survey focuses on Vietnamese businesses involved in preparation of the integrated report and other stakeholders. Its findings show a low level of knowledge about IR in Vietnam, however, the majority of stakeholders are eager to learn more about it. Most businesses in Vietnam have not yet discovered its benefits as well as its implementation process. Therefore, it is necessary to equip knowledge and provide technical support through training, coaching, conferences, seminars, etc. Study purpose: This study is aims at exploring the stakeholders’ views on in Vietnam an emerging economy in Southeast Asia. Study motivation: IR and its benefits have been widely accepted all over the world, however, in Vietnam, only a few businesses have adopted it. This study explores its causes, thereby proposing solutions to promote its adoption in Vietnam. Study design, approach and method: The study explores the stakeholders’ views through a survey of 200 subjects including report makers and other stakeholders. Key findings: The findings show that knowledge about IR in Vietnam is low, however the majority of stakeholders are eager to learn more about it. The stakeholders are uncertain about the role of the current reporting system, but they think that IR will help improve the disclosure. Practical significance: The limited knowledge of IR may keep the Vietnamese business from adopting IR. Equipping IR knowledge and providing technical support is necessary to make IR more popular, thereby providing a transparent financial market, attracting the attention of various international investors.
High-Sensitivity GPS - the Low Cost Future of GNSS ?!

SUMMARY In general it has to be distinguished between GPS receivers and evaluation techniques used by surveyors, and the mass market solutions. Main difference is the accuracy that can be reached. During the last years two developments have taken place that may change the attitude of a surveyor regarding this separation. On the one hand research and implementation regarding use of low cost GPS receivers for geodetic purpose is on the way. In future this may lead to a merger of these two application fields. On the other hand the mass market gets more interesting as a working field for surveyors. The latter is connected with the catch words wireless-assisted GPS and more recently high-sensitivity GPS. These new technologies allow to establish a higher availability of GNSS signals in urban canyons or even indoor. An overview about these technologies is given in this paper as well as an insight into the respective market. The paper deals with quality characteristics like availability and accuracy of high sensitivity GPS receivers as well as navigation receivers. Recent results obtained at University Stuttgart are presented. As expected availability increases, but accuracy is reduced, if low quality signals are tracked. Additionally the possibilities for the geodetic community to reach “geodetic” accuracies are outlined based on new results using low cost receivers. ZUSAMMENFASSUNG Im Allgemeinen ist zwischen hochgenauen GPS Empfangern und Auswertetechniken und den Massenmarktlosungen zu unterscheiden; insbesondere aufgrund der erreichbaren Genauigkeit. In den letzten Jahren haben zwei Entwicklungen stattgefunden, die die Einstellung des Vermessers hinsichtlich dieser Trennung andern konnten. Einerseits wird der Einsatz von Low Cost GPS Empfangern fur geodatische Anwendungen erforscht. Andererseits steigert sich die Attraktivitat des Massenmarkts fur den Vermesser. In diesem Zusammenhang spielen die Schlagworter wireless-assisted und high-sensitivity GPS eine grose Rolle. Diese neuen Technologien erlauben eine hohere Verfugbarkeit von GPS Signalen in Strasenschluchten oder sogar innerhalb von Gebauden. Der Beitrag gibt sowohl einen Uberblick uber diese Technologien als auch einen Einblick in die jeweiligen Marktsegmente. Der Beitrag beschaftigt sich mit Qualitatsmerkmalen wie Verfugbarkeit und Genauigkeit von High-Sensitivity GPS Empfangern und Navigationsempfangern. Wie erwartet steigt die Verfugbarkeit bei gleichzeitiger Reduktion der Genauigkeit, wenn schwache GPS Signale genutzt werden.
Ionizing radiation effects on phosphorus implanted N/sup +/ poly gate MOS capacitors with thin gate oxides

Radiation effects on phosphorus implanted N/sup +/ poly-gate MOS capacitors with a 15-nm oxide grown at different temperatures are investigated. The dependence of the radiation hardness of thin gate oxides on the oxidation temperature as a function of the irradiation bias is investigated, and the results obtained are compared with those of previous studies for both thick and thin oxides. It is shown that the response of the gate oxide depends on the temperature of the phosphorus implant anneal for n/sup +/ poly implanted gate with an implant energy of 50 keV. A qualitative model is proposed to explain the negative trapping exhibited in the oxides of the capacitors which received an 850 degrees C implant anneal. The model suggests that these electron traps are related to the phosphorus concentration and its electrical activation in the oxide due to the implant anneal temperature. >
What is the impact of Work-From-Home (WFH) Arrangements on the Quality of Life (QoL)?

The ongoing pandemic has forced countries’ education systems to continue to operate in a fragile and uncertain environment. Given the limited existing literature regarding the pandemic’s impact on the Quality of life (QoL) for teachers, this study aims to bridge the gap and provide a detailed analysis of how the extent of providing online courses and time to transition online during the pandemic could impact a tertiary educator’s QoL. The factors defining the dependent variable, QoL, were derived from past studies and made applicable within the confines of our research. The independent variables are the amount of time spent working online, notice to transition online, and various control variables. The study will utilize cross-sectional data collated by conducting convenience and volunteer sampling surveys with Embry-Riddle Aeronautical University (ERAU) faculty in campuses around the world. The data will be analyzed through regression analysis and ANOVA test. The findings of the study will aid in the development of government and educational policies to ensure the future sustainability of the education workforce in the unknown endemic landscape.
Students’ Perceptions of ESP Academic Writing Skills through Flipped Learning during Covid-19

Learners studying English for Specific Purposes (ESP) at University regard writing academic papers as a complex process since they have to consider issues about academic writing conventions as well as ethics. This current research examines university students’ perceptions of ESP academic writing within the context of the online learning which emerged due to Covid-19 and, therefore, through the Information and Communication Technologies (ICT) and, particularly, utilizing the Flipped Learning approach as an active learning strategy to enhance ESP academic written competence. To be more specific, we examined how students, in tertiary education, perceived ESP academic writing skills within the field of Business English. The participants are 28 students doing the Degree in Administration and Business Management in a Spanish polytechnic. A mixed method research has been conducted for this current paper since both quantitative as well as qualitative methods were utilized for data collection. Regarding this study, both a questionnaire and a focus group interview were utilized to analyse the data. The outcomes proved that students’ perceptions towards academic ESP written competence, using Business English, within the Flipped Learning approach was positive. The major results showed students’ awareness of their needs and ESP written requirements. This research concludes with some future research suggestions.
EFFECT OF SOME PRE AND POSTHARVEST TREATMENTS ON THE KEEPING QUALITY OF POINSETTIA CUT FLOWERS: I: EFFECT OF DIFFERENT FERTILIZATION REGIMES AND IRRIGATION LEVELS ON THE VEGETATIVE, ROOT GROWTH, FLOWERING AND CHEMICAL COMPOSITION OF PLANTS.

A comprehensive postharvest study on poinsettia cut flowers was carried out during the two successive seasons of 1997/98 and 1998/99 at the Veget. and Flor. Dept., Faculty of Agriculture, Mansoura University to evaluate the effect of a Super Grow fertilizer at 0.0, 0.3, 0.6 and 0.9 g/plant once weekly combined with different irrigation levels of 150, 300, 450 and 600 ml/plant once every 3 days and different flower holding solutions as follows : sucrose (15 g/L), silver nitrate (25 ppm), boric acid (10 ppm), citric acid (10 ppm) and their interaction on vase life and quality of cut poinsettia flowers. The obtained results indicated that the heaviest flowers weight (19.87 %) resulted from treated plants with the fertilizer at 0.9 g/plant, irrigated with 450 ml/plant combined with holding flowers in citric acid (10 ppm) + sucrose (15 g/L) solution. Moreover, the highest water uptake (3.26 ml/fl), the best positive water balance (0.94 ml/fl./day) and the longest vase life (19.75 days) were produced from plants treated with the fertilizer at 0.9 g/plant, irrigated with 450 ml/plant and combined with holding flowers in silver nitrate (25 ppm). However, the fertilized plants with 0.3 g/plant and irrigated with the minimum water level of 150 ml/plant showed almost half the vase life prementioned (9.0 day) when hold in water only in the first season. The present study recommended that applying Super Grow fertilizer at 0.9 g/L once every week, with irrigation level at 450 ml/plant once per 3 days and combined with holding flowers in silver nitrate (25 ppm) to obtain the longest vase life and best quality of poinsettia cut flowers.
Political Information Use and Its Relationship to Beliefs in Conspiracy Theories Among the German Public

This study investigates how exposure to different news sources, propensity to vote (PTV) for a party and demographics are related to belief in conspiracy theories drawing on three repeated cross-sectional surveys in Germany 2017–2019. Results show that frequent exposure to alternative news sites and video-sharing platforms increased conspiratorial beliefs. Frequency of exposure to the quality press, public service TV news, and news aggregators diminished beliefs in conspiracy theories. Exposure to TV news, legacy media online, tabloids, social media, and user comments was unrelated to such beliefs. PTV for far left and right parties increased conspiratorial beliefs, moderate party preference reduced them.
The role of the bill-of-materials as a CAD/CAPM interface and the key importance of engineering change control

The BoM (bill-of-materials) which is essentially a structured parts list, is generated automatically by most modern CAD systems and is used by the CAPM system to explode the master production schedule (MPS) into both gross and net component requirements. The role of the bill-of-materials is central to the integration of computer-aided design and computer-aided production management systems. Increasingly specific customer demands often involve significant changes to the bill-of-materials. The authors explain the implications of engineering change control on the bill-of-materials and the CAD/CAPM interface. Case studies illustrate the success of introducing engineering change control to integrate manufacturing and design systems. >
Evaluation of Rehabilitation of Surgically Repaired Flexor Hand Tendons and Ultrasonographic Follow up of Their Healing

Objectives: To evaluate the role of early rehabilitation of surgically repaired flexor hand tendons in improvement of clinical outcome and the role of musculoskeletal ultrasound in follow up of their healing. Patients and methods: Thirty patients with 31 repaired flexor tendons. Assessment was done after 2nd, 4th,8th and 12th weeks of rehabilitation by visual analogue scale (VAS), total active motion of injured fingers (TAM), grip strength, hand assessment tool (HAT) score and ultrasound (US). Results: There was a significant development in pain assessed by VAS, TAM, grip strength and HAT score of the affected hand (p<0.001). Ultrasonographic assessment of healing flexor tendons showed significant improvement in defect size, thickness, vascularity, echogenicity and margination. There was positive correlation between margination of healing flexor tendon with VAS, hand grip and HAT score. Conclusions: Application of proper rehabilitation programs has a great impact on improving the functional outcome after surgical repair of flexor hand tendons. High-frequency ultrasound is used to follow up tendon healing after surgical repair and to assess the state of tendon repair in relation to clinical result.
High reliability GaAs MESFET for suppressed hot-electron-induced degradation of high efficiency power amplifiers

As a result of channel recess engineering, GaAs MESFET breakdown voltage was improved with minimal sacrifice of device RF performance. The dc breakdown voltages defined at gate current of 1 mA/mm as high as 21.5 V were achieved for the MESFETs with increased channel recess width. A consistent increase in breakdown voltage was observed at RF by using the waveform probing technique. The new MESFET offers suppression of hot-electron effects for improved reliability of high-efficiency power amplifiers with an estimated order of magnitude increase in device lifetime.
Acceleration Characteristics of Starting Vehicles

Acceleration characteristics of starting vehicles are needed for many transportation analysis and design purposes involving driveways, turning bays, intersecting streets, traffic signals, railroad crossings, simulation software, and so forth. Constant acceleration is sometimes assumed, or AASHTO Green Book values based on piecewise-constant accelerations are sometimes adopted. However, continuing research has shown that linearly decreasing acceleration rates better represent both maximum vehicle acceleration capabilities and actual motorist behavior. It is not acceleration that usually is constant during speed changes; it is the rate of change in acceleration. The evolution of AASHTO acceleration values for design is traced, and the literature is reviewed for pertinent field observations. Linearly decreasing acceleration (and some deceleration) model parameters are calibrated for various sets of observational and design data. Despite published results from thousands of field measurements, the values selected for design were found to be based mostly on vehicle performance capabilities, with conjecture about how many of these capabilities are normally used by drivers. Design accelerations were found to deviate substantially from observed accelerations. At the start of motion, observed accelerations were about 15 percent faster for passenger cars and 45 percent faster for SU (single unit) trucks than design accelerations. As speed increased, observed accelerations dropped three to four times faster than design accelerations for these vehicles. Observed accelerations for WB-15 trucks began 40 percent to 75 percent slower than design accelerations, and they were considerably slower than the values in the Green Book for trucks at railroad crossings. Voids in the available information base are identified. Linearly decreasing design acceleration rates for motorists operating different classes of vehicles in different design situations are recommended, and revisions for Green Book parameters and charts are suggested. The recommended acceleration model greatly simplifies acceleration parameters but implies using different acceleration relationships for different design speeds instead of one for all.