Miracle-dz/UniFAR-FTUs huggingface dataset:
GREEN SYNTHESIS OF SILVER NANOPARTICLES USING GLYCINE MAX SEEDS AQUEOUS EXTRACT AND STUDY OF ITS ANTI-DEPRESSANT ACTIVITY AGAINST FORCED SWIM TEST

of ABSTRACT Present study investigates the synthesis of silver nanoparticles using aqueous extract Glycine max (AEGM) and evaluating its antidepressant activity in forced swim test (FST) by using amitriptyline as a standard anti-depressant drug. Synthesized Silver Nanoparticle from Aqueous Extract of Glycine max (SNAEGM) were characterized by advanced techniques like UV, XRD, SEM, FTIR and Zeta potential, and its anti-depressant potential by FST. Successful synthesis of SNAEGM by ecofriendly and low cost method was justified by change of color of solution to dark brown, appearance of peak at 440nm in UV spectroscopy, average particle size with in nano range by XRD and SEM, zeta potential of -12.9mV and appearance of functional group bands of different plant phytoconstituents in FTIR. Control group animals showed increased immobility time which was significantly (p<0.0001) decreased in amitriptyline (20mg/kg), AEGM (200mg/kg) and SNAEGM (160mg/kg). Moreover it was observed that SNAEGM was more effective in decreasing immobility time as compared to AEGM and amitriptyline. Thus we conclude Glycine max is effective tool for synthesis of nanoparticles and have potential anti-depressant activity. Further research is required to explore the in-depth molecular mechanism involved in treatment of depression.
University of Birmingham Archipelagos and meta-archipelagos

The term meta-archipelago has been in use in cultural studies for some time, to refer to certain complex island areas in which the boundaries between conventionally recognised archipelagos are indistinct, although the concept also carries additional connotations. Use of the term in biogeography appears more recent and without effort to prescribe its meaning. We outline, from a biogeographical perspective, distinctions between meta-archipelagos and archipelagos and those islands not occurring within either collective grouping, highlighting that network analysis tools provide metrics for formal analytical purposes. others. The Ke Islands are described with this group on account of their ethnology, though zoologically and geographically they belong to the Moluccas…”
Spontaneous Regression of Atypical Primary Cutaneous Diffuse Large B-Cell Lymphoma on Cheek upon Methotrexate Withdrawal

Primary cutaneous diffuse large B-cell lymphoma (PCDLBCL) accounts for approximately 6% of all cutaneous lymphomas. PCDLBCL are usually seen in leg, however they can be seen in other location in 15% of cases.It usually affects elderly women and is associated with poor prognosis.Solitary lesions are relatively rare. The recommended treatment is as for systemic diffuse large B-cell lymphoma (DLBCL). We present an atypical case of PCDLBCL occurring on the cheek of an elderly woman and its spontaneous resolution upon withdrawal of methotrexate therapy for rheumatoid arthritis. It is paramount to recognise these cases and correlation being undertaken in order to avoid inappropriate chemotherapy.
Effect of Hydroalcoholic Extract of Centella Asiatica and its Synergy with N–Acetyl Cysteine on Marble– Burying Behavior in Mice: Implications for Obsessive– Compulsive Disorder

Traditionally, Centella asiatica Lin. (CA) whole plant is used as anti– compulsive, memory enhancing, anxiolytic and antidepressant effects. However, no scientific validation is available on the anti–compulsive potential of the plant. To reduce the doses of CA and N–acetyl cysteine combination study was also carried out to target two different neurotransmitters. This study was carried out to examine the effect of CA whole plant hydroalcoholic extract and its combination with N–acetyl cysteine on marble–burying behavior test. Mice from different groups were administered with vehicle, CA (50, 100, 200 or 500 mg/kg), N–Acetyl–L–Cysteine (NAC) (25, 50, 100 or 200 mg/kg) and fluoxetine (5, 10 or 20 mg/kg). One hour after CA and thirty minutes after NAC or fluoxetine administration, individual mice was subjected to marble burying test for thirty minutes and actophotometer for ten minutes. CA (200 and 500 mg/kg, p.o.), NAC (100 and 200 mg/kg, p.o.) and fluoxetine (10 and 20 mg/ kg, p.o.) significantly inhibited marble–burying behavior in mice. Moreover, in separate experiments, co–treatment with sub–effective dose of both CA (50 or 100 mg/kg, p.o.) and NAC (25 or 50 mg/kg, p.o.) significantly decreased marble–burying behavior at doses, which either of these alone could not protect the behavior. All dose levels of CA, NAC and fluoxetine showed insignificant changes in locomotor activity in actophotometer. Our results reveal that Centella asiatica possesses anti–compulsive activity and co–administration of CA with nutraceutical N–acetyl cysteine also show synergistic effects in reducing obsessive–compulsive behavior in mice.
Topics in supersymmetry and physics beyond the standard model

OF THE DISSERTATION Topics in Supersymmetry and Physics Beyond the Standard Model by Jean-Francois Fortin Dissertation Director: Professor Thomas Banks In this thesis we explore different aspects related to the central concepts of supersymmetry and physics beyond the Standard Model. We start by investigating fine-tuning in the minimal supersymmetric extension of the Standard Model, where the regions with the minimal amount of fine-tuning of electroweak symmetry breaking are found. Afterwards, we concentrate on a more formal aspect of supersymmetry, studying spontaneous symmetry breaking in supersymmetry using the superspace formalism. Thereafter we direct our attention to supersymmetry as physics beyond the Standard Model, looking more specifically at supersymmetry breaking in metastable states. First, we discuss possible undetected Higgs decays in the Pentagon model with renormalizable lepton number violating couplings which also explain neutrino masses. Second, we generalize metastable supersymmetry breaking in supersymmetric quantum chromodynamics to phenomenologically viable models of direct gauge mediation by adding single and multitrace deformations. Third, we introduce a new model of physics beyond the Standard Model, the Pyramid Scheme, and study its implications, focusing on dark matter and its astrophysical signatures in particular. Four, we examine tunneling constraints in models of Cosmological Supersymmetry Breaking, arguing that these models can have no supersymmetric vacuum states in the infinite Planck mass limit. Finally, we present a general study of the possible gamma ray signatures coming from dark matter annihilation or decay.
How to survive the brief water-coverage of vernal ponds? Early hatching date and rapid larval development in Aeshna affinis (Odonata: Aeshnidae)

The objective of our study was to identify mechanisms enabling typical inhabit-ants of vernal ponds in temperate climate zones to complete their larval development under the time-constrained conditions of temporary larval habitats. We compared both hatching phenology and larval development of Aeshna affinis with those of its permanent water congener A. mixta under semi-natural conditions and with literature data on other European Aeshnidae. We identified the following traits enabling rapid univoltine development in vernal ponds: i) Seasonally early hatching: A. affinis hatched significantly – on average 22 days – earlier than A. mixta . ii) Relatively small size difference between the second and the final larval stadium: Second-stadium larvae of A. affinis were significantly larger than those of all other European Aeshnidae, but the exuviae are among the smallest of this family in Europe. Therefore, larval growth coefficient and the number of larval stadia are smaller than in any other European Aeshnidae. iii) A low degree-day sum during larval development, being significantly lower than that of A. mixta. Although median larval development time of the vernal pond species A. affinis was longer than that of A. mixta , the first emerged significantly – on average 18 days – earlier than the latter.
Administering Email Usage: A Cross Case Analysis of Experiences with Electronic Monitoring and Control in Eastern Region of Ghana

An email system is a critical business tool. However, as electronic business activity increases, ad-hoc email implementation, prolonged management neglect and user abuse of email systems have generated negative effects. Anticipating, managing and preventing these negative effects has become increasingly important as organizations struggle to derive benefits from these systems. Many organizations try to control the negative effects of email through a combination of policies and electronic monitoring. However, monitoring can be contentious and policies are often inadequate. This paper presents the results of a multiple case study investigation of email system monitoring and control in four organizations. The study highlights the need to formulate a coordinated and comprehensive response consisting of technical, formal and informal controls. The study reveals the effectiveness of email management committees, training, policies, and sustained awareness when combined with email monitoring. The paper concludes by identifying key factors for effectively monitoring and controlling email usage.
Previously Uncharacterized,* WA-) solates from an Investigation of Canine Pneumonia

Mycoplasmas recovered from the respiratory tract and genitourinary system of dogs, with and without respiratory infection, have been characterized by biological and immunological methods. Some of the isolates were identified as being similar to the three species of canine mycoplasmas described earlier under the designation Mycoplasma spumans, M. canis, and M. maculosum. Other mycoplasmas placed in three groups (A, C, and D) were found to be clearly distinct from the three classified species. Group A strains fermented glucose but not mannose and were serologically distinct from other canine mycoplasmas recovered in this study. These strains were subsequently found to be biologically and serologically related to a previously reported, but unclassified, canine mycoplasma. Group D strains differed in some biological properties but were serologically related. These were found to be nonfermenting mycoplasmas representing isolations from the throat and bladder of dogs. They were serologically distinct from other canine mycoplasmas and were apparently unrelated to other known mycoplasma serotypes. Group C mycoplasmas were recovered only from the lungs of dogs. Within the group, they differ in some immunological properties but appear to be serologically distinct from other canine strains. They can also be separated from other dog strains in their ability to ferment glucose and mannose. Group B strains were found to have biological properties similar to M. canis strains but seemed to be
Content Contribution for Revenue Sharing and Reputation: A Dynamic Structural Model

This study examines the incentives for content contribution in social media. we propose that exposure and reputation are the major incentives for contributors. Besides, as more and more social media web sites offer advertising-revenue sharing with some of their contributors, shared revenue provides an extra incentive for contributors who have joined revenue-sharing programs. we develop a dynamic structural model to identify a contributor’s underlying utility function from observed contribution behavior. we recognize the dynamic nature of the content-contribution decision—that contributors are forward-looking, anticipating how their decisions affect Published in Journal of Management Information Systems, 2012, 29 (2), 41-76. DOI: 10.2753/MIS0742-1222290203 42 TANg, gu, AND whINSTON future rewards. using data collected from YouTube, we show that content contribution is driven by a contributor’s desire for exposure, revenue sharing, and reputation and that the contributor makes decisions dynamically.
The Simultaneous Optical-toX-ray Spectral Energy Distribution of Soft X-ray Selected AGN observed by Swift

We report Swift observations of a sample of 92 bright soft X-ray selected active galactic nuclei (AGN). This sample represents the largest number of AGN observed to study the spectral energy distribution (SED) of AGN with simultaneous optical/UV and X-ray data. The principal motivation of this study is to understand the SEDs of AGN in the optical/UV to X-ray regime and to provide bolometric corrections which are important in determining the Eddington ratio L/LEdd. In particular, we rigorously explore the dependence of the UV-EUV contribution to the bolometric correction on the assumed EUV spectral shape. We find strong correlations of the spectral slopes αX and αUV with L/LEdd. Although Narrow-Line Seyfert 1 galaxies (NLS1s) have steeper αX and higher L/LEdd than Broad-Line Seyfert 1 galaxies (BLS1s), their optical/UV to X-ray spectral slopes αox and optical/UV slopes αUV are very similar. The mean SED of NLS1s shows that in general this type of AGN appears to be fainter in the UV and at hard X-ray energies than BLS1s. We find a strong correlation between αX and αUV for AGN with X-ray spectral slopes αX<1.6. For AGN with steeper X-ray spectra, both this relation and the relation between αX and L/LEdd break down. At αX≈1.6, L/LEdd reaches unity. We note an offset in the αUVL/LEdd relation between NLS1s and BLS1s. We argue that αUV is a good estimator of L/LEdd and suggest that αUV can be used to estimate L/LEdd in high-redshift QSOs. Although NLS1s appear to be highly variable in X-rays they only vary marginally in the UV. Subject headings: galaxies: active
Using Audio Lingual Method to Improve Students Pronunciation Ability of Darul Mahdiah Private School

This study aims at finding out how the use Audio Lingual Method through Repetition Drill Technique improves Thai students’ pronunciation ability. This is a Classroom Action Research (CAR) conducted in Darul Mahdiah private school Songkhla-Thailand. The subjects of the study are 16 Thai students of class 6/2 at the school. The data were collected from pronunciation tests and analyzed by using percentages analysis. The result of the students’ pronunciation improvement was as follows; in the pre-pronunciation test the students’ pronunciation score was 0% (excellent), 0% (very good), 31.25% (good), 31.25% (low) and 37.5% (failed), in the cycle 1 post test the score was 0% (excellent), 14.29% (very good), 50% (good), 21.42% (low) and 14.29% (failed), and the score of the cycle 2 post test was 6.25% (excellent), 37.5% (very good), 43.75% (good), 12.5% (low) and 0% (failed). This leads to the conclusion that the students’ improved pronunciation was due to the two reasons; first, the students’ pronunciation ability improved through repetition drill since they got used to pronounce words intelligibly as what the teacher modeled. Keywords: audio lingual method, repetition drill, pronunciation, thai students
Clinical Study Expression and Function of Ephrin-B1 and Its Cognate Receptor EphB2 in Human Abdominal Aortic Aneurysm

We examined the expression of ephrin-B1 and its cognate receptor EphB2, key regulators of angiogenesis and embryogenesis, in human abdominal aortic aneurysm (AAA) and analyzed their functional roles in cell migration. From 10 patients (9 males and 1 female; age, 68 . 5 ± 2 . 4) who underwent vascular surgery for AAA, we obtained AAA and adjacent control tissues. Using real-time RT-PCR, we analyzed expression of ephrin-B1 and EphB2. We also histologically localized these molecules in AAA tissues. Finally, e ﬀ ects of ephrin-B1 and EphB2 on inﬂammatory cell chemotaxis were examined by cell migration assay. Expression levels of ephrin-B1 (0 . 410 ± 0 . 046 versus 1 . 198 ± 0 . 252, P = 0 . 027) and EphB2 (0 . 764 ± 0 . 212 versus 1 . 272 ± 0 . 137, P = 0 . 594) were higher in AAA than normal control. Both ephrin-B1 and EphB2 were expressed in macrophages, T lymphocytes, and endothelial cells within AAA. In chemotaxis assay, ephrin-B1 and EphB2 inhibited mononuclear-cell chemotaxis induced by stromal derived factor-1 down to 54 . 7 ± 12 . 7% ( P = 0 . 01) and 50 . 7 ± 13 . 1% ( P = 0 . 01), respectively. These data suggest that ephrin-B1 and EphB2 might be functional in human adult inﬂammatory cells and involved in the pathogenesis of AAA, although speciﬁc roles of these molecules should further be sought.
Effect of Third Party Funds and BI Rate on Credit Distribution of BNI

This study aims to examine the effect of third-party funds and BI Rate to Bank BNI lending in the period of 2010 until the third quarter of 2016 with multiple linear regression analysis methods. The results of this research to produce numbers R square of 98.5% means that independent variables can explain 98.5% of the dependent variable and the rest is explained by other variables not examined by the independent variables used simultaneously significant effect on lending. While partially, third party funds and a significant positive effect on credit distribution mean when the deposits rise, the loan portfolio also increased and vice versa. While the BI Rate has no effect on credit in a positive direction. The suggestions that could be recommended include increasing third party funds by improving the performance of employees or gift for the customer in order to get more fund: Optimization lending to the public in accordance with the function of the bank; and using regression analysis with a distributed lag models for further research so that better results.
Risk and risk management in the credit card industry (cid:2)

Using account-level credit card data from six major commercial banks from January 2009 to December 2013, we apply machine-learning techniques to combined consumer tradeline, credit bureau, and macroeconomic variables to predict delinquency. In addition to providing accurate measures of loss probabilities and credit risk, our models can also be used to analyze and compare risk management practices and the drivers of delinquency across banks. We ﬁnd substantial heterogeneity in risk factors, sensitivities, and predictability of delinquency across banks, implying that no single model applies to all six institutions. We measure the eﬃcacy of a bank’s risk management process by the percentage of delinquent accounts that a bank manages effectively, and ﬁnd that eﬃcacy also varies widely across institutions. These results suggest the need for a more customized approached to the supervision and regulation of ﬁnancial in- stitutions, in which capital ratios, loss reserves, and other parameters are speciﬁed individually for each institution according to its credit risk model exposures and forecasts.
Doubly-Weighted Pseudo-Almost Periodic Functions

We introduce and study a new concept called doubly-weighted pseudo-almost periodicity, which generalizes the notion of weighted pseudo-almost periodicity due to Diagana. Properties of such a new concept such as the stability of the convolution, translation-invariance, existence of a doubly-weighted mean for almost periodic functions, and a composition result will be studied.
Effect of Andrographis paniculata on Ion Transport in Human Respiratory Epithelium

Andrographis paniculata , also known as Fah Talai Jone in Thailand, is an herb traditionally used in China, India and Southeast Asia. It has been widely used for centuries, for the treatment of respiratory infection and common cold. However, the effect of Andrographis paniculata in regulating ion transport in respiratory epithelium is currently has not well understood. Thus, the present study was aimed to determine the effect of Andrographis paniculata on ion transport in human respiratory epithelium using NCI-H441 cell line using Ussing chamber technique. The equivalent short-circuit (I sc ), an indicator of ion transport across the epithelium was calculated. The results showed that Andrographis and CFTR Cl channel blockers. Taken together these findings suggest that Andrographis paniculata increases Na + absorption via ENaC without any effect on Cl - secretion in H441 cells. 5 µg/ml 100 U/ml The cells were maintained in 75 cm 2 flasks and incubated in a of 5 % CO 2 at 37 until they reach 70 % confluence before plating on Snapwell For Ussing chamber studies, the cells were plated on Snapwell at the density 250,000 cells/insert and grown in RPMI 1640 medium supplemented with 100 nM dexamethasone. After seeding for 24 hr, apical side of the cells were washed and 100 µl of fresh media added whereas the bottom compartment of the Snapwell were filled with 1.5 ml of fresh media and subsequently changed every 48 hr. Monolayers were incubated for 4-5 days until tight junctions were developed. Ussing chamber study: Ussing chamber technique was used to determine the equivalent short-circuit current representing ion transport property of H441 cell monolayers grown on permeable supports (Snapwell). The Ussing chamber is separated into two compartments, apical and basolateral, divided by the monolayer. Each half of the chamber was filled with physiological bathing solution containing (in NaCl (130), KCl (4), H-HEPES (5), Na + HEPES (5), MgCl 2 (1), CaCl 2 (1) and glucose (5); pH 7.4. The chamber was connected to a data acquisition system (PowerLab 4/30, ADInstruments, New South Wales, Australia) and a high impedance device to prevent current to be drawn from the circuit by equipment. Transepithelial potential difference (V te ) was monitored continuously using a Chart V 7 program with reference to the basolateral side of the epithelium. Transepithelial resistance (R te ) was determined by applying short (200 ms) current pulses (3 µA, period 6 s). The equivalent short-circuit current (I sc ) was calculated according to Ohm’s Law (I = V/R). Short-circuit current was allowed to stabilize for approximately 10 min before performing the experiment.
Nevirapine Signiﬁcantly Reduces the Levels of Racemic Methadone and ( R )-Methadone in Human Immunodeﬁciency Virus-Infected Patients

Methadone is metabolized by various isoforms of the cytochrome P450 family, which can be induced by many drugs, including nevirapine. The objective of the present study was to determine the effects of coadministration of nevirapine and methadone on the dose-adjusted areas under the concentration-time curves (AUCs) of racemic and ( R )-methadone. Twenty-ﬁve human immunodeﬁciency virus-infected subjects taking stable single daily doses of racemic methadone or ( R )-methadone were included in this prospective, single-crossover trial. At the baseline, nevirapine was either started as part of a new regimen containing two nucleoside reverse transcriptase inhibitors (NRTIs) or added to an ongoing NRTI regimen. Patients could increase their methadone doses if withdrawal symptoms developed. Twelve-hour pharmacokinetic proﬁles were obtained before and 28 days after the start of nevirapine treatment. The total concentrations of methadone and its inactive metabolite, 2-ethylidene-1,5-dimethyl-3,3-diphenylpyrrolidine (EDDP), in serum were determined by liquid chromatography-tandem mass spectrometry. Among the 20 evaluable patients, coadministration of nevirapine signiﬁcantly decreased the mean dose-adjusted AUC of methadone by 41%. AUC reductions were similar for patients taking racemic methadone (37%; n (cid:1) 11) and ( R )-methadone (44%; n (cid:1) 9). AUC changes ranged from mild increases in three patients to decreases of up to 70%. Fourteen of 20 patients required additional methadone due to withdrawal symptoms. However, the median dose increase was only 15%, which was less than that which would have been expected from the pharmacokinetic data. The AUC of EDDP increased signiﬁ- cantly, by 35%. Methadone dose adjustments are justiﬁed when methadone is coadministered with nevirapine. Due to extensive variability, the adjustments must be tailored to the individual patient’s needs.