Miracle-dz/UniFAR-FTUs huggingface dataset:
ANALYSIS OF PARTIAL DIALLEL CROSS FOR YIELD AND IT’S COMPONENTS IN DURUM WHEAT

Eight parents of durum wheat were crossed using partial diallel cross method in the 2008/2009 growing season. The eight parents and their 12 F1 progenies were grown in the 2009/2010 at the Farm of the College of Agriculture, Duhok University, Iraq using a Randomized Complete Block Design with three replications to estimate the general combining ability of the parents, gene action, heritability and heterosis for yield and its components. The results showed highly significant differences among genotypes for all the studied characters. The parent LD 357 E had a positive general combining ability effect in most characters including grain yield. The dominance was greater than additive genetic variance in most the characters. Heritability in narrow sense was high for days to 75% flowering, 1000-kernel weight and grain yield/plant besides expected genetic advance was high for all characters. Maximum number of hybrids showed significant positive heterosis for 1000-kernel weight and grain yield/plant and the hybrid [Dour 29× LD 357 E] had the highest positive heterosis for most studied characters including grain yield.
IL-17A, IL-17E and IL-17F as Potential Biomarkers for the Intensity of Low-Grade Inflammation and the Risk of Cardiovascular Diseases in Obese People

Low-grade inflammation is a factor that predisposes to many obesity-related comorbidities. The immune mechanisms controlling the inflammatory response related to the secretory activity of adipocytes and its consequences for the organism are still under investigation. Methods: 84 obese adult volunteers (BMI ≥ 30 kg/m2) were tested by BIA. Serum samples were collected to analyze the concentrations of interleukins IL-17A, IL-17E and IL-17F. The subjects completed the original questionnaire, the FFQ-6 food consumption frequency questionnaire and the food diary. Results: The level of IL-17E and IL-17F was positively correlated with the BMI value and the level of IL-17E increased with the content of subcutaneous fat. Its increased blood concentration was also observed in individuals who declared that they were diagnosed with atherosclerosis and/or were taking beta-blockers. Products that were related with a low level of the above-mentioned interleukins were vegetables, groats, eggs, red meat, fast-food and alcohol. The level of these interleukins was positively correlated with the frequent consumption of confectionery and breakfast cereals. Nutrients that decreased the concentrations of IL-17 isoforms were potassium, iron, vitamins B6 and C, and folic acid. Conclusions: Both IL-17E and IL-17F may be closely related to the intensity of low-grade inflammation and be biomarkers of cardiovascular disease risk. Food products or the nutrients they contain may affect the levels of the above-mentioned interleukins as well as IL-17A.
Testing the measurement invariance of perceived freedom scale by gender

Studies that aim to point out structural differences between groups assume that the measurement tool will function similarly, and thus the results of such measurements will have similar psychometric features. Hence, this study aimed to test the measurement invariance (MI) of the construct validity of the Perceived Freedom in Leisure Scale (PFLS). The research sample consisted of 1097 university students (480 women and 617 men). The MI of the PFLS was tested by multigroup confirmatory factor analyses that test the invariance of the covariance structures within the scope of structural equation modeling. The study yielded evidence which indicates that the measurement model defined for the factor structure of the scale provides MI in terms of gender. The fit indexes for formal invariance, which is the first phase of MI, are χ2 /df = 1.48; CFI = . 97; NFI = . 91; and RMSEA = . 065. Meanwhile, the study observed that a value regarding metric, scalar, and strong invariances, which pertain to other phases of MI, is within acceptable limits (≤−.01 ∆CFI ≤.01). According to the results, we can deduce that the items on a psychological measurement tool represent the same psychological structure among groups.
A Longitudinal 3D Investigation on Facial Similarity among Two Monozygotic Twins in Their First Childhood: An Application of the 3D-3D Facial Superimposition Technique

Children affected by orofacial disorders mix functional alterations with morphological problems, and suitable techniques should be devised for their analysis. Stereophotogrammetry and 3D-3D facial superimposition have already proven to reliably assess morphological differences even between twin siblings, separating the effect of genetic and environmental factors. However, little information is available about twin babies. We longitudinally analyzed a couple of healthy monozygotic twin sisters aged 6 months to 5 years (height time points). The entire 3D facial models of the two sisters were registered according to the least point-to-point distance, and the relevant RMS (root mean square) distance between the facial models was calculated at each time and compared with reference data recorded from adult twins (Mann-Whitney test, p < 0.05). RMS values in the twin sisters were on average 1.18 ± 0.21 mm, and 1.86 ± 0.53 mm in adults, with a significant difference (p < 0.01). Results showed that twins are more similar in early childhood when environmental factors are supposed to have not influenced facial morphology sufficiently. Additionally, the technique seems adequate to detect even small differences: the faces of the twin sisters were not fully identical. 3D-3D facial superimposition techniques can objectively quantify facial dissimilarity even in monozygotic twins. The method may be applied to the faces of twins discordant for some orofacial and maxillofacial pathology and potentially separate genetic and environmental factors.
I am ‘better’ than you! The influence of upward social comparison on the intention to work abroad among doctors in Iraq: the mediating mechanism of attitude towards leaving

Abstract The primary objective of the study was to verify the possibility that social comparisons occurred between professionals (i.e. doctors) in their country of origin to similar others in different hospitals, healthcare systems, and countries. In addition, this study also examined whether these social comparisons resulted in an intention to work abroad among these professionals who remained in their home country. On a sample of 450 Iraqi doctors, we used Structural Equation Modeling through partial least squares (PLS-SEM) to analyse the data. Our study found that upward comparison and attitude towards leaving positively affected the intention to work abroad among doctors who remained in Iraq. Further, the relationship between upward comparison and intention to work abroad was mediated by attitude towards leaving. Our study extends the brain drain literature by examining the role of social comparison, specifically upward comparison, in the migration of professionals and how such a comparison leads to intention to work abroad. The implications for theory and practices to reduce such a comparison among professionals are discussed.
The problem of evaluating primary school students in the online education process

Distant education studies carried out during the COVID-19 pandemic period are handled at different education levels and from different perspectives. The purpose of this research is to evaluate the problem of evaluation of primary school students in online education with the opinions of teachers. This research was carried out by using qualitative research methods. The study group of the research consisted of 25 classroom teachers working in various primary schools in Almaty, Kazakhstan, in the 2021-2022 academic year. A semi-structured interview form was used as a data collection tool in the research. As a result of the research, teachers stated that face-to-face education is more advantageous than distance education in the evaluation of students. The teachers categorized the problems they encountered in the field of measurement and evaluation during the distance education process as technical problems, communication problems, method problems, and student problems. They suggested technical support, communication support, choosing the appropriate method, and motivating the students as the solution to the problems. Keywords: Distance education; evaluation; online education; teacher opinions
Oral intake of a new full-spectrum hyaluronan improves skin profilometry and ageing: a randomized, double-blind, placebo-controlled clinical trial

Skin aging is a physiological condition which leads to structural and functional changes in skin. Common signs of aging are the gradual decrease of hyaluronic acid (HA) in the skin and the appearance of wrinkles. Therefore, effective HA supplementation could counteract HA deficiency and improve skin parameters, providing a safe profile for use which is easily incorporated into daily routine. To evaluate a food supplement containing a wide range of hyaluronans of different molecular weights (full-spectrum hyaluronan [FS-HA]) in order to ameliorate skin conditions in adult females. Sixty subjects showing mild-to-moderate skin aging signs were enrolled in a double-blind, randomized, placebo-controlled clinical trial to receive 200 mg/day of FS-HA (ExceptionHYAL® Star), or placebo, for 28 days. Dermatological parameters were evaluated at T0d and T28d. Product efficacy and tolerance were further evaluated using a self-assessment questionnaire. In addition, HA serum levels were weekly evaluated in a proportion of enrolled subjects. After only 28 days, subjects in the active arm showed a statistically significant improvement in all evaluated dermatological parameters related to skin aging. Skin became more hydrated (+10.6%) and protected from dehydration, with a decrease in both wrinkle depth −18.8%) and volume (−17.6%) and increase in elasticity and firmness (+5.1%). Instrumental results were further confirmed by self-assessment questionnaire outcomes. Administration of a food supplement based on innovative hyaluronans from bio-fermentation, characterized by a wide range of molecular weights, resulted in a quick and significant amelioration of typical signs of skin aging.
Relationship between Nursing Students’ Clinical Learning Environment Satisfaction, their Self-Efficacy and Academic Achievement

The clinical practice is the most significant element of nursing education, which must be practiced in suitable setting. The worth of Clinical Learning Environment is a valid indicator to confirm the value of nursing curriculum. The quality of patient care is only reasonable, if nursing staff have acquired high quality of clinical training during their nursing education and their employment years. Objective: Identify the relationship between nursing students’ Clinical Learning Environment satisfaction, their self-efficacy, and academic achievement. Setting: Six clinical training Hospitals namely: Alexandria Main University Hospital, Alexandria New University Hospital, Alexandria Students' University Hospital, El Shatby Pediatric Hospital, El Shatby Obstetric Hospital, and El Maamoura Psychiatric Hospital. Subjects: Nursing students enrolled in different nursing courses and affiliated to Faculty of Nursing – Alexandria University during their four consecutive academic years were recruited in this study (n=324). Tools: Clinical Learning Environment Inventory (CLEI) and College Academic Self-Efficacy Scale (CASES), and Personal Data Tool. Results: More than two thirds of the students were satisfied with their Clinical Learning Environment. Statistically significant positive correlation between Nursing students’ Clinical Learning Environment satisfaction, their SelfEfficacy and Academic Achievement in nursing courses existed and also, between students’ study year in nursing Faculty, Clinical training specialty, clinical training unit and Clinical Learning Environment satisfaction. A statistically significant positive correlation was detected between students’ age, study year in nursing Faculty, type clinical training hospitals, clinical training specialty, type clinical training units and their levels of self-efficacy. Conclusion: Nursing students highlighted negative areas that could be taken into consideration by the faculty members to enhance the Clinical Learning Environment. There is statistically significant positive correlation between Nursing students’ Clinical Learning Environment satisfaction, their Self-Efficacy and Academic Achievement in nursing courses. Recommendations: Measurement of nursing students’ satisfaction about the Clinical Learning Environment should be conducted in a compassionate and nonthreatening manner. Staff development programs for clinical instructors are needed to promote their skills in providing effective clinical training for nursing students. Opportunities should be allowed for nursing students to express their opinions about effectiveness of Clinical Learning Environment. The clinical instructors should assist nursing students to solve the problems facing them in the Clinical Learning Environment.
An International Professional Development Collaboration: Supporting Teachers in the Kingdom of Saudi Arabia through an Immersion Program in the United States

The Kingdom of Saudi Arabia (KSA) recently initiated multiple, one-year, school immersion programs to help 25,000 KSA teachers better support KSA students and the KSA education system after spending time abroad in teacher education programs throughout the United States (US). This study explored the effects of one such program, aimed at helping KSA teachers become agents of change. The authors examined how the 46 KSA teachers involved in this program changed. Survey-research and English language tests were used to show that the immersion program yielded its desired effects: the program increased teachers’ sense of efficacy; improved teachers’ pedagogical, content, technical, and English language skills; and enhanced teachers’ understandings of education across nations and cultures, with emphasis on the transfer of features of the US educational system back to the KSA (although teachers were uncertain about the extent to which the transference desired might actually occur). Via supplemental interviews, the authors also identified self-reported influential sources of change. The article examines how these sources of change impacted KSA teachers’ mindsets regarding their teaching. The study confirms that the program influenced participants through their school immersion experiences, given that the program offered KSA teachers chances to learn more about student-centered learning approaches and more customized and individualized care for students.
Effects of calorie restriction on reactive oxygen species production by mitochondrial reverse electron transport, mitochondrial permeability transition pore, and beta-adrenergic stimulation during cardiac hypertrophy

Calorie restriction is a nutritional intervention that reproducibly protects against the maladaptive consequences of cardiovascular diseases. Pathological cardiac hypertrophy leads to cellular growth, dysfunction (with mitochondrial dysregulation), and oxidative stress. The mechanisms behind the cardiovascular protective effects of calorie restriction are still under investigation. In this study, we addressed the impact of calorie restriction on mitochondria, oxidative stress markers, and β-adrenergic signaling during cardiac hypertrophy. This dietetic intervention prevented cardiac protein elevation, decreased atrial natriuretic peptide levels, and blocked the increase in heart weight per tibia length index seen in isoproterenol-induced cardiac hypertrophy. Our data suggest that inhibition of cardiac pathological growth by calorie restriction is accompanied by a lower mitochondrial reactive oxygen species formation and improved mitochondrial content. We also found that superoxide dismutase and glutathione peroxidase activities negatively correlate with cardiac hypertrophy. Calorie restriction also attenuated the opening of the Ca2+-induced mitochondrial permeability transition pore in mitochondria isolated from isoproterenol-treated mice. Isoproterenol (a β-agonist) increases cardiac rate (chronotropic response) and force of contraction (inotropic response). Given the nature of cardiac hypertrophy induction by isoproterenol, we tested whether calorie restriction could change the cardiac β-adrenergic sensitivity. Using isolated rat hearts in a langendorff system, we found that calorie restriction mice (similar to controls) have preserved β-adrenergic signaling. On the flipside, hypertrophic hearts (treated for seven days with isoproterenol) were insensitive to β-adrenergic activation using isoproterenol (50 nM). Despite protecting against cardiac hypertrophy, calorie restriction did not alter the lack of responsiveness to isoproterenol of isolated hearts harvested from isoproterenol-treated rats. These results suggest (through a series of mitochondrial, oxidative stress, and cardiac hemodynamic studies) that calorie restriction possesses beneficial effects against hypertrophic cardiomyopathy. However, it may lack effects on some of the hypertrophic consequences, such as β-adrenergic signaling repression.
Association of the PECAM-1 (Leu125Val) and P-Selectin (Thr715Pro) Gene Polymorphisms With Unexplained Spontaneous Miscarriages

Introduction: The aim of this study was to investigate the possible effect of the PECAM-1-C373G (Leu125Val) and P-Selectin-A37674C (Thr715Pro) polymorphisms in unexplained spontaneous abortions. Methods: In a case-control design, Greek nulligravida women with recurrent idiopathic miscarriages <20 weeks of gestation and fertile controls were genotyped by pyrosequencing. Results: There was no significant association of the PECAM-1-C373G (Leu125Val) polymorphism with recurrent abortions. Although the P-Selectin-A37674C (Thr715Pro) polymorphism was not associated with miscarriages overall, the association was statistically significant for younger women (carriers of the P-Selectin-37674C allele: <35 years: odds ratio (OR) = 3, 95% confidence interval (CI): 1.13-7.97, p = 0.023; <30 years: OR = 6.75, 95%CI: 2.02-22.58, p = 0.002). In comparison with CC/AA genotype, the combined carriers of the PECAM-1-373G and P-Selectin-37674C alleles had OR =8.81 (95%CI: 1.07-72.50, p = 0.024). The association of the coexistence of the two polymorphisms was stronger in younger women (<35 years: OR = 12.07, 95%CI: 1.38-105.68, p = 0.014; <30 years: OR = 65, 95%CI: 3.38-1251.28, p = 0.001), and late (OR = 10.64, 95%CI: 1.16-97.60, p = 0.024) and second-trimester miscarriages (OR = 26, 95%CI: 1.84-367.71, p = 0.014). The association between carriage of the P-Selectin-37674C allele and recurrent miscarriages was significant for younger women. Conclusion: The coexistence of the PECAM-1-373G and P-Selectin-37674C alleles increased the miscarriage risk for the total population studied, suggesting an interaction between the two polymorphisms, more pronouncedly in younger women and the association was stronger for late fetal loss.
Effect of Simvastatin on Alcohol Induced Hepatitis in Experimental Rat

to prevent or cure alcohol-induced liver disease (ALD) at any stage. Consequence, therapeutic solutions are still a key requirement for those patients. The current study was intended to evaluate the effect of simvastatin in ethanol induced hepatitis and its progression. We demonstrated that chronic drinking of ethanol significantly elevated liver enzymes which were decrease upon simvastatin treatment, indicating its ameliorative effect. TG level was increased in alcohol induced hepatitis group when compared to normal control group and supplementation with simvastatin showed insignificant decrease of serum TG. However, there is insignificant change in the serum total cholesterol in the present model of alcohol induced hepatitis and the results represent the reversal of hypercholesteremia after 55 days. These results suggest simvastatin could prove not beneficial in the prevention or treatment of ALD.
Effect of Nursing Intervention Package on Prevention of Uterine Prolapse among Pregnant Women in Third Trimester

Background: Uterine prolapse occurs when the uterus descends towards or through the opening of the vagina below its normal anatomical position. Aim of study: Was to evaluate effect of nursing intervention package on prevention of uterine prolapse among pregnant women in third trimester. Design: A quasi experimental design was utilized to fulfill the aim of the study: two groups were studied (study and control group) with pre, post and follow up test. Setting: The study was conducted at obstetrics and gynecology outpatient clinic at Benha university hospital. Sample: A purposive sample of 90 women was selected according to the inclusion criteria. Tools of data collection: Four tools were included, a structured interviewing questionnaire sheet, women's reported practices sheet toward prevention of uterine prolapse, modified Likert scale and assessment tool for uterine displacement. Results: There were a highly statistical correlation between total knowledge, total practices, and total attitude among studied women (study and control groups) as (p ≤0.000) and (p ≤ 0.006) . Also women who applied the nursing intervention package (study group) had no degrees of uterine prolapse in the follow up test. Conclusion: There was a highly statistical improvement in the study group than control group regarding the total level of knowledge, practice and attitude about prevention of uterine prolapse posttest. Recommendation: Develop awareness programs for the pregnant women to improve their knowledge, practice and attitude about uterine prolapse.