Miracle-dz/UniFAR-FTUs huggingface dataset:
Nutritional and technological characteristics of common and spelt wheats are affected by mineral fertilizer and organic stimulator NANO-GRO

The effect of biostimulators on plants affects an increase in the level of plant resistance to stress factors which normally occurs in plants, while under non-stress conditions it affects better utilization of the genetically conditioned potential. Based on the field experiments conducted in the years 2011-2013 at the Experimental Station in Tomaszkowo, the effect of mineral fertilization and an organic plant growth stimulator, NANO-GRO®, was determined on the height of grain yield and its components, on the content of macro- and microelements and technological quality (protein and its fraction composition, starch, gluten, Zeleny index, hardness and bulk density) in the grain of common wheat and spelt. The combined application of basic mineral fertilization (NPK) with an organic growth stimulator, NANO-GRO®, had no effect on the grain yield and its components in common wheat and spelt, except increasing 1000 grain weight in spelt. Additional spraying of plants with preparation NANO-GRO® contributed to an increase in the content of P, Ca, Cu, Mn, Zn, a decrease in Mg content in spelt grain, an increase in the amount of Cu, Fe, and a decrease in Mg, Ca, Mn in wheat grain. It also caused an increase in the content of protein, gluten and Zeleny index, and a decrease in bulk density in common wheat grain. The content of starch increased in spelt grain, while the content of protein, gluten and grain hardness decreased. The amount of enzymatic proteins (albumins and globulins) increased in both cereals, while the amount of glutenins (as a result of a decrease in low molecular weight fractions, LMW) increased in spelt grain. An increase in gliadins was observed (ω, α/β, γ) as well as a decrease in the total glutenins (as a result of a decrease in LMW fractions) in common wheat grain. The use of the growth stimulator NANO-GRO® favorably affected the ratio of gliadins to glutenins in spelt grain.
Progress in the Design of Molecular Targeted Drugs for Gastric Cancer

Gastric cancer is one of the most common cancers in China, and its pathogenesis is related to many molecular signaling pathways and related factors. The more critical molecular pathways include MET pathway, PI3K / AKT pathway, and MAPK pathway. In addition, the EGFR family and factors related to tumor angiogenesis are also important factors, which are closely related to tumor cell proliferation, apoptosis, and metastasis. The results of the study will provide new ideas and methods for the treatment of gastric cancer and lay the groundwork for the development of new gastric cancer drugs. On this basis, a variety of molecular targeted drugs have entered the clinical trial stage, among which, trastuzumab and apatinib have shown good efficacy. This paper summarizes the molecular pathogenesis of gastric cancer, and summarizes the mechanism of action, combination chemotherapy and research progress of trastuzumab and apatinib, so as to provide reference for future research on targeted therapy for gastric cancer.
Comprehensive comparison of clinicoradiological, laboratory, and prognostic factors of community-acquired pneumonia in diabetic and nondiabetic hospitalized patients

Background/aim Community-acquired pneumonia (CAP) is one of the leading infectious causes of mortality, and diabetes mellitus is a globally prevalent disease. Consequently, the cooccurrence of these two disorders can be common and create challenging medical conditions. Therefore, it was aimed to compare the various aspects of CAP in diabetic and nondiabetic patients, in order to have a comprehensive and comparative picture of the differences. Materials and methods In this cross-sectional study, CAP patients with and without diabetes were assessed for clinicoradiological signs, laboratory features, disease severity, and pneumonia outcomes. Results Analyzed herein were 172 CAP patients (77 had diabetes and 95 were nondiabetic). Clinical and radiological signs of pneumonia were mostly similar between the groups, except for purulent sputum, which was more prevalent among the nondiabetic patients. The laboratory results were also mostly similar. However, analysis of the outcomes and prognosis showed different results. The diabetic patients had a longer mean duration of hospital stay (8.52 days vs. 7.93 days, p = 0.015), higher median pneumonia severity based on the CURB-65 criteria (3 vs. 2, p = 0.016), and higher intensive care unit (ICU) admission requirement (22.1% vs. 7.3%, p = 0.004). Moreover, the mortality rate for the diabetic patients was nonsignificantly higher (16.8% vs. 15.7%, p = 0.453). Furthermore, the results of the logistic regression analysis showed that the diabetic patients had significantly higher odds of experiencing more severe forms of pneumonia (adjusted odds ratio (AOR): 5.77, 95% CI: 2.52–13.20), requiring ICU hospitalization (AOR: 3.56, 95% CI: 1.39–9.11), and having a longer hospital stay (AOR: 2.01, 95% CI: 1.09–3.71). In addition, although there was no significant relationship between the severity of pneumonia and the amount of glycated hemoglobin (HbA1c) in the diabetic patients (p = 0.940), the higher level of HbA1c in the nondiabetic patients was significantly correlated with a higher severity of pneumonia (p = 0.002). Conclusion While diabetic patients with CAP have the same clinicoradiological and laboratory features as nondiabetic patients, the presence of diabetes can significantly worsen the outcomes and prognosis of pneumonia.
Digital Commons @ University of Digital Commons @ University of South Florida South Florida

In 2015 Dr. Pratiksha Vaghela started the “Stop Poking Me” campaign which was aimed at curbing the increase in the number of needlesticks at the James A. Haley Veteran Affairs Hospital (JAHVA). The data for needlesticks was collected by the Occupational Medicine Clinic (OMC) between Oct 2013 and Oct 2016. We then obtained the original data from Dr. Vaghela’s project and compared the data to assess whether the new implementations have truly decreased the number of needlesticks. There was a 23.6% reduction in the number of needlesticks between 2013 and 2016 and even more importantly a 60.1% reduction between 2015 and 2016. Our project shows that the decrease correlates to the implementation of the “Stop Poking Me” campaign.
Clutter and Map Legibility in Automated Cartography: A Research Agenda

Abstract:The clutter effect occurs when there is an excessive amount of information in a map or when this information is disorganized. Measurement of clutter is essential to improve the quality of outputs produced using automated cartographic systems. This paper reviews some existing methods for measuring clutter from different research communities, highlighting the lack of suitable methods for use in automated map design. Three use cases are presented to show what kind of clutter measures are needed to go further with the automation of map design, particularly in generalization, in symbol/style specification, and in heterogeneous data integration and visualization. One measure cannot capture all the aspects of clutter, and combination of clutter measures at each step of the whole map design process should be investigated for automated cartography. A research agenda for clutter assessment regarding some specific cartographic processes is provided. Résumé:L’effet de clutter intervient lorsqu’une carte comporte une quantité excessive d’informations ou, que les informations qu’elle comporte manquent d’organisation. Il est indispensable de savoir mieux mesurer la complexité qui en résulte, afin de contrôler la qualité des cartes produites grâce à des processus automatiques. Dans cet article, nous présentons des méthodes de mesure de cette complexité qui sont actuellement utilisées par différents chercheurs, et nous montrons qu’elles ne sont pas adaptées à la conception automatique de cartes. Nous présentons trois cas d’utilisation pour illustrer le type de mesures requis pour améliorer la conception des cartes, particulièrement en matière de généralisation, de spécification du style cartographique et d’intégration et de visualisation de données disparates. Il en ressort notamment qu’une seule mesure ne peut pas saisir tous les aspects de la complexité des cartes, et qu’il faudrait donc envisager d’utiliser la combinaison de différentes mesures à chaque étape de la conception automatisée d’une carte. Nous suggérons des recherches qui permettraient d’établir des moyens de mesurer la complexité liée à certains processus cartographiques.
Molecular analysis of the S-RNase in self-incompatible Solanum chacoense

Self-incompatibility (SI) is the inherited ability of a fertîle hermaphrodite flowering plant to prevent seif-fertilization by blocking the growth of pollen tubes on or inside the pistil. SI constitutes a prezygotic barrier present in about half of the Angiosperm families, and is one of the most widespread evolutionary devices used by flowering plants to prevent inbreeding depression by promoting gene exchange within a species. This cell-ceil recognition mechanism, by far more complex than previously imagined, involves finely tuned pollen-pistil interactions under the control of elements of the 5-locus. As a result, self-incompatible plants reject selfbut accept non-self pollen. Solanaceae, Rosaceae and Scrophulariaceae families display gametophytic SI (GSI), where the breeding behavior of the pollen is determined by its own haploid genotype. Controlled by a single multigenic S-Iocus, the pistillar-expressed determinant to SI in these familles is a polymorphic RNase (S-RNase), a glycoprotein secreted in the extracellular matrix of the style. The pollen determinant to S-RNase-mediated SI has only recently been identified as an F-box encoded by the so-called S haplotype-specific F-box gene (SFB) or S-locus F-box gene (SLF), according to the various authors. In our first study we tried to understand why diploid pollen containing two different pollen determinants is typically self-compatible. We generated S11S11S13S13 tetraploids and analyzed the behavior of their pollen on pistils of transgenic plants expressing a dual-specific S11113-RNase. If the compatibility were due to lack of pollen-S gene expression (silencing), the S11S13 pollen produced by the SlISHS13S13 tetraploids would be compatible with the transgenic plants. Alternatively, if competitive interaction between SH and S13 pollen-S components present together in diploid pollen takes place, the Sj;S13 pollen should be rejected by the transgenic plants, because our dual-specific S11113-RNase rejects both SH and S. pollen. Since the genetic analysis revealed full rejection 0f S11S13 pollen, we concluded that the pollen components of the SI system are fully expressed in diploid heterozygous pollen.
Ancestral role of Fat-like cadherins in planar cell polarity

Fat family cadherins are enormous proteins that regulate planar cell polarity (PCP) and cell adhesion in bilaterian animals. Their evolutionary origin can be traced back to prebilaterian species, but their ancestral function(s) are unknown. We identified Fat-like and Dachsous cadherins in Hydra, a member of the early-diverging metazoan phylum Cnidaria. Hydra has a simple body plan with only two epithelial layers and radial symmetry. We find that Hydra homologues of Fat-like (HyFat) and Dachsous (HyDs) co-localize at the apico-lateral membrane of ectodermal epithelial cells. Remarkably, HyFat is planar polarized perpendicular to the oral-aboral axis of the animal. Using knockdown approaches we found that HyFat is involved in the regulation of local cell alignment, but is dispensable for the global alignment of ectodermal myonemes along the oral-aboral axis. The intracellular domain (ICD) of HyFat is involved in the morphogenesis of ectodermal myonemes. Thus, Fat family cadherins have ancient, prebilaterian functions in cell adhesion, tissue organization and planar polarity.
Image Emotion Analysis Combining Attention Mechanism and Multi-level Correlation

The development of social network has brought a large amount of image information, and the research on image emotion has gradually attracted wide attention. The current image emotion analysis methods based on multi-level features simply splice the features at each level and then classify the emotions, which not only ignores the correlation between features at different levels, but also ignores the synergistic effect between global features and local features. Therefore, this paper proposes an emotion model (MAML) based on mixed attention and multi-level dependence of images, which uses spatial and channel attention mechanisms to extract local emotion region features of images. Bi-directional Long Short Term Memory network (BiLSTM) is used to establish correlation between multi-level image global features. The experimental results of MAML model on artphoto and abstract data sets prove the validity of MAML model.
Consciousness and Prospects of Autoclaved Aerated Concrete (AAC) Blocks for Wall Construction: Comparative Study Nigeria and South Africa

Autoclaved Aerated Concrete Block (AACB) is a viable, sustainable walling material for building projects but has not been given the attention it deserves in developing countries. To increase the usage of AACB on building projects, this study examines the consciousness and prospects for its use in Nigeria and South Africa. The objectives are (i) to evaluate the degree of knowledge about AACB, (ii) the variants in Nigeria and South Africa, and to assess the likelihood of adopting AACB in Nigeria—the study centres on Lagos and five provinces in South Africa. Lagos was chosen in Nigeria because the State is the only place in Nigeria where AAC blocks have been used. A total of 145 questionnaires were administered to professionals who had been involved in AAC projects. In contrast, 17 South African respondents familiar with AACB in construction projects were polled online using Google Forms. Convenience and snowball sampling procedures were used for construction professionals in both countries. Data were analysed using Statistical Package for the Social Sciences (SPSS) version 23.0. Statistics such as percentages and mean scores were explored using analysis of variance (ANOVA) and the Mann-Whitney U test. Findings indicate that construction professionals in Nigeria know very little about 19 of the 20 documented AACBs. However, the South African professionals are very knowledgeable about AACB grade 42.5 OPC and AACB of AP/RHA and fully aware of AACB with grade 52.5 OPC, though they know nothing about the Bamboo Leaf Ash (BLA) AACB. This means that Nigerian professionals have a moderate stance on using AACB. The study concludes that South African Builders are more aware of AACB and its variants than Nigeria. This implies that AACB manufacturing in Nigeria would not thrive in the construction market due to poor patronage since patronage is directly related to product awareness. The study, therefore, suggests that building construction professionals should increase their understanding of AACB through continuous development training, workshops, and seminars on environmentally friendly building materials. Another suggestion is for consultants, clients, developers, contractors, governments, and research institutions to continuously conduct research and embrace findings on the AACB and new building construction materials regarding usage, wear, tears and durability.
Ursodeoxycholic Acid Prophylaxis and the Reduction of Gallstone Formation After Bariatric Surgery: An Updated Meta-Analysis of Randomized Controlled Trials

Gallstone formation following bariatric surgery poses a significant clinical concern, prompting various preventive strategies, including ursodeoxycholic acid (UDCA) prophylaxis. This systematic review and meta-analysis aimed to assess the efficacy of UDCA in preventing gallstone formation after bariatric surgery. A comprehensive literature search was conducted in major databases up to September 2023, identifying 12 randomized controlled trials (RCTs) meeting the inclusion criteria. The studies, spanning from 1993 to 2022, involved 2,767 patients who underwent diverse bariatric procedures. The primary outcome was the overall incidence of cholelithiasis, with secondary outcomes encompassing gallstone occurrences at three, six, and 12 months; symptomatic cholelithiasis; and rates of cholecystectomy. The Cochrane risk-of-bias tool was utilized for evaluating study quality, and statistical analyses were conducted using the RevMan software (Cochrane Collaboration, London, UK). Patients receiving UDCA demonstrated a significantly lower overall incidence of gallstones post-bariatric surgery (risk ratio [RR] 0.13; P < 0.0001). Subgroup analyses confirmed reduced gallstone incidence at three months (P = 0.04), six months (P < 0.00001), and one year (P < 0.00001) with UDCA prophylaxis. Symptomatic cholelithiasis incidence was also lower in the UDCA group (RR 5.70; P < 0.00001), and cholecystectomy rates were significantly reduced (RR 3.05; P = 0.002). This meta-analysis supports the efficacy of UDCA prophylaxis in preventing gallstone formation after bariatric surgery. The findings suggest that UDCA administration not only lowers overall gallstone incidence but also reduces the occurrence of symptomatic cholelithiasis and mitigates the need for cholecystectomy. However, caution is warranted due to heterogeneity, diverse surgical procedures, and limited long-term follow-up in the included studies. Further research with standardized protocols and extended observational periods is recommended to strengthen the evidence base and guide clinical practice.
STI pathogens in the oropharynx: update on screening and treatment

Purpose of review The rise in antimicrobial resistance in several STI pathogens such as Neisseria gonorrhoeae has become a public health threat as only one first-line treatment remains. Reducing screening interval for gonorrhoea and chlamydia in high-prevalence populations has been proposed to address antimicrobial stewardship, but this remains controversial. This review aimed to revisit the epidemiology of infections at the oropharynx and review the current screening recommendations and treatment guidelines in different populations. Recent findings Emerging evidence suggests that the oropharynx is the primary anatomical site for gonorrhoea transmission but maybe not for chlamydia transmission. Most international guidelines recommend 3-monthly oropharyngeal gonorrhoea and chlamydia screening for high-prevalence populations (e.g. men who have sex with men) but not low-prevalence populations (e.g. heterosexuals) given the clinical and public health benefits of screening in low-prevalence populations are still unclear. Doxycycline remains the first-line treatment for oropharyngeal chlamydia in most guidelines. However, some countries have moved from dual therapy (ceftriaxone and azithromycin) to monotherapy (ceftriaxone) for oropharyngeal gonorrhoea treatment to address antimicrobial stewardship. Summary The transmission of gonorrhoea and chlamydia is still not fully understood. Further work will be required to evaluate the benefits and harms of reducing screening in high-prevalence populations.
The effect of decision making related rationalization on fraud and the mediating role of psychosocial work environment

This study aims to examine the influence of the psychosocial work environment on the proclivity for asset misuse in the context of local government management, with a focus on the perceptions of administrators in Central Sulawesi Province. Employing purposive sampling, a total of 39 government units constituted the study's population, with a final sample size of 114 participants, comprising administrators, officers, and managers. WarpPLS software was employed to analyze the data. The findings reveal a positive relationship between rationalization and the inclination toward asset misuse. Additionally, rationalization exhibits a negative impact on the psychosocial work environment. Finally, the psychosocial work environment demonstrates a negative influence on the propensity for asset abuse. These outcomes suggest that the psychosocial work environment plays a pivotal role in mitigating the inclination for asset misuse within the local government of Central Sulawesi Province. This research sheds light on the significance of fostering a positive psychosocial work environment to enhance decision-making processes and reduce the likelihood of fraudulent activities in the management of government assets. Understanding these dynamics is crucial for the development of strategies to promote ethical and responsible asset management in local government entities.
Incidence and Determinants of Diarrheal Cases in Children Under Five Admitted at Kampala International University Teaching Hospital, IshakaBushenyi District, Western Uganda

Diarrhoea stands as a significant global public health issue, with the WHO reporting approximately 2.5 billion cases annually among children below five years old. This study aimed to ascertain the prevalence of diarrhoea and its influencing factors in children under five admitted to Kampala International University Teaching Hospital (KIU-TH). Employing a cross-sectional and descriptive approach, quantitative data was gathered through selfadministered and investigator-led questionnaires, utilizing digital tools such as Google Sheets for data collection. A total of 238 mothers, randomly selected using convenience sampling, whose children were admitted at KIU-TH constituted the study's sample. The results, presented through 95% Confidence Intervals (C.I), Odd Ratios (OR), and P-values, were computed using Binary Logistic Regression with Pearson’s correlation in SPSS Version 26, and graphically represented using Microsoft Excel Software. At the time of data collection, the prevalence of diarrhoea among children under five admitted at KIU-TH stood at 24.4% based on maternal responses. This high prevalence was found to be influenced by several factors, including the child's vaccination status, the early introduction of supplementary foods, premature weaning practices, and the child's age. Notably, exclusive breastfeeding practices were not adhered to, with mothers introducing other foods at a young age and initiating early weaning practices. Keywords: Diarrhoea, Children under five years of age, Vaccination status, early weaning.
FOOD HABITS OF NESTING GOLDEN EAGLES (AQUILA CHRYSAETOS) ON SANTA CRUZ AND SANTA ROSA ISLANDS, CALIFORNIA

Between 2000 and 2007, we studied food habits of golden eagles (Aquila chrysaetos) nesting on Santa Cruz and Santa Rosa islands by analyzing prey remains recovered from 11 nests—7 on Santa Cruz Island and 4 on Santa Rosa Island. We collected 464 prey items representing 28–30 species. Based on biomass, the most important prey for golden eagles before feral pigs (Sus scrofa) were eradicated from the islands were feral piglets (31.4%), mule deer (Odocoileus hemionus) fawns and elk (Cervus elaphus) calves (18.0%), common raven (Corvus corax; 17.4%), cormorants (Phalacrocorax sp.; 10.3%), and gulls (Larus sp. 6.7%). There were island-specific differences both in species and biomass of prey. On Santa Cruz Island, the eagles’ diet consisted of feral pigs (63.2%), gulls (13.3%), and common ravens (8.9%); while on Santa Rosa Island the eagles’ diet consisted of mule deer fawns (34.6%), common raven (25.8%), cormorants (14.2%), and waterfowl (8.6%). Prior to removal of feral pigs, island foxes (Urocyon littoralis) and feral piglets comprised 5.9% and 63.2% of the biomass found in the eagle nests on Santa Cruz Island; however after removal of feral pigs, we found a greater proportion of island foxes (45.7–57.7%), common ravens (24.7–26.7%), and gulls (18.0–19.5%) in the nest remains. The depauperate nature of the vertebrate prey on the islands has resulted in golden eagles foraging on a number of prey species not typically eaten by eagles elsewhere in North America such as island fox, western spotted skunk (Spilogale gracilis), feral piglets, mule deer fawns, common raven, barn owl (Tyto alba), gulls, and cormorants.