Miracle-dz/UniFAR-FTUs huggingface dataset:
Drug interactions of oral anticoagulants

Background: Oral anticoagulants (OACs) are the drugs of choice where long-term anticoagulation is needed due to convenience of dosing. But their use has potential for several drug interactions. Monitoring for potential interactions with timely management will decrease the risk of complications of anticoagulation.Methods: We aimed to assess the presence of potential drug-drug interactions in patients on oral anticoagulants for various indications. Prescriptions of a cohort of patients on oral anticoagulants were analyzed. Potential drug interactions were identified using free software available at www.drugs. com and classified into major, moderate and minor types.Results: Of the 135 patients in the study, 83 were males and mean age was 52.9±17.3 years. Most commonly used OACs were vitamin K antagonists (VKAs) (80.0%) followed by direct oral anticoagulants (DOACs) (20.0%). Median number of concomitant medications per patient was 4 (IQR 3-6). A total of 307 potential interactions were identified in 121 patients with a median of 2 interactions per patient. Of the 56 patients who had potential for major drug interactions, 45 (41.6%) were on VKAs and 11 (40.7%) on DOACs had potential to develop major interactions. Using logistic regression model, significant predictors of major drug interactions were age>60 years (OR 2.50; 95% CI 1.05-5.95; p=0.04) and presence of venous thromboembolism VTE (OR 0.09; 95% CI 0.02-0.55; p=0.01). Conclusions: This hospital-based study showed potential drug interactions with OACs. Age more than 60 years and presence of VTE were significant predictors of major interactions. Awareness of potential interactions and monitoring doses of OACs help to prevent complications of therapy.
Auto-correlation function of PD pulses under electrical treeing degradation

Pulse correlation in PD signals was analyzed with auto-correlation function of PD pulses occurring in tree channels at 50 Hz ac voltage application as well as PD pulses occurring in several simple model electrodes. It was clarified that the auto-correlation function of PD pulse trains was strongly affected by void shape including tree length. It was found that even simple model electrodes, which showed very similar /spl phi/-q distribution patterns to those of tree channels, had different auto-correlation functions from those of PD pulse trains of tree channels. The results suggest that the auto-correlation function may give additional information about the PD mechanism to that given by the /spl phi/-q distribution patterns. >
Rice as an alternative feed ingredient in swine diets

Abstract It has become important to explore alternative feed ingredients to reduce feed costs, which are burdensome for livestock production. In addition, it is desirable to find efficient and functional alternative ingredients for traditional feed ingredients in pig diets, considering the stress and sensitivity of disease of pig. Rice is produced around the world like corn that is the typical energy source in pig diets. Although the nutritional quality varies depending on the degree of milling, rice, except whole grains (paddy rice), contains more starch than corn and its structure and granule size are easier to digest than corn. In addition, the fact that rice has fewer non-starch polysaccharides (NSP) and anti-nutritional factors (ANFs) is also effective in improving digestibility and various polyphenols in rice can help modulation of immune responses, which can be beneficial to the gastrointestinal environment and health of pig. Many studies have been conducted on rice focusing on things such as degree of milling, substitution rates of corn, granule size, and processing methods. Most results have shown that rice can be partially or completely used to replace corn in pig diets without negatively affecting pig growth and production. While further research should focus on the precise biological mechanisms at play, it was confirmed that the use of rice could reduce the use of antibiotics and pig removal and protect pigs from gastrointestinal diseases including diarrhea. From this point of view, rice can be evaluated as a valuable feed ingredient for swine diets.
BODY IMAGE, SELF-ESTEEM AND QUALITY OF SEXUAL LIFE AMONG WOMEN AFTER HYSTERECTOMY

Background: Hysterectomy is particular type of surgery, which can influence the patient's life. In fact, deciding to undergo hysterectomy is a difficult process for every woman, especially psychologically. Aim: This study aims to investigate the relation between body image, self-esteem and quality of sexual life among women after hysterectomy. Subjects and Method: A descriptive correlational research design was used. The study was conducted at outpatient clinic of Oncology Center of Mansoura University. The study involved 188 women with hysterectomy. Tools of data collection: used four tools; body image scale, selfesteem scale, Quality of sexual life questionnaire and an interview questionnaire. The data was collected through an interview questionnaire. Results: Revealed that above half of women with hysterectomy was high concern with body image, majority of women with hysterectomy had high level of self-esteem and above three quarters of women reported being satisfied with their sexual life after hysterectomy. Conclusion: There was a strong positive correlation between patient's body image and self-esteem also, positive correlation between patient's self-esteem and quality of their sexual life. The main recommendation: Suggested is initiating comprehensive health educational programs as well as rehabilitation programs for all women following cancer treatment in outpatient's clinics of oncology department units should be held, including psychological, social and physical relatedissues.
Prediction of Mortality Incidence in Patients with Chronic Kidney Disease Based on Influential Prognostic Factors with Competing Risks Approach

Background: Chronic Kidney Disease (CKD) is a disease in which the kidney’s functionality declines gradually. The aim of this study was to identify significant laboratory prognostic factors on death due to CKD in a clinical complex. Materials and Methods: A retrospective study including 109 patients with the end-stage renal disease treated at Iran Helal pharmaceutical and the clinical complex was conducted between 2014-2018. The survival time was set as the time interval between starting dialysis until death due to CKD. Also, the transplantation was considered as competing risk, which was occurred for a few patients. A three-parameter Gompertz model was used that considers both the event of interest and the competing event simultaneously. Results: Death due to CKD occurred in 29 (26.6%) of the patients and 19(17.4%) with transplantation. Serum uric acid was a significant prognostic factor that decreased the hazard of mortality by 21%. Serum phosphorus and age by increasing the risk of death, were poor prognoses for the event of interest. Serum uric acid and phosphorus 6.9-9.9 (mg/dl) were associated with 72% and 4.05- fold increased hazard of transplant, respectively. The 4-year cumulative incidence of death and transplant was 48.4% and 29.2%, respectively. Conclusion: We have deduced that high serum phosphorus levels and increased levels of age were associated with worse outcomes. High serum uric acid level was related to better survival, which could be explained by having a better protein-rich diet alongside the high albumin level.
Multi-stakeholder collaboration in Urban Living Labs

Urbanization is spreading at a rapid pace, putting cities under heavy pressure with environmental issues such as global warming resulting from CO2 emission. A sense of urgency to find solutions is consequently widespread, and society at large is striving to find suitable and inventive ways to adapt. As a result, Urban Living Labs (ULLs) have emerged. By comparing three different ULLs in Norway, this thesis aims to see how different actors, consisting of political, private, academic, and public stakeholders, work together to co-create sustainable mobility solutions. Through the use of an analytical framework consisting of the Quintuple Helix Model, four values of co-creation, and four roles of citizens, this thesis hence seeks to explore why and how the stakeholders collaborate, and what role the citizens are perceived to have in such collaboration. The research suggests that the reason why stakeholders collaborate is mainly to achieve social innovation by challenging existing social frameworks. This overarching goal can further be backed up by an underlying focus on product and service innovation and how this can enhance efficient and sustainable outcomes. How the collaboration take form is characterized by the creation of a sharing culture, which focuses on bringing out the best of each other through building on each stakeholders’ strength and expertise. The responsible stakeholder for connecting citizens seems, however, to be unclear, mostly varying between political and private stakeholders. It is further emphasized that the lack of experience with citizen involvement hinders the ULLs’ potential of collaborating with the citizens. Consequently, a cultural shift appreciating collaboration with multiple stakeholders, i.e. multi-stakeholder collaboration, is required. Additional factors influencing the collaboration potential of enhancing knowledge creation are political budgets, laws, and time. The role of the citizens in the collaboration appears to range from being testers of products to being active contributors to the development process, where the latter is most common. It is ultimately argued that ULLs are currently being shaped by elements from both New Public Management and New Public Governance, forming the motivations, structures, and roles of the collaboration. As a result, hereof ULLs are seen to work as initiatives that facilitate a collaborative approach towards urban governance.
Study of the multilayer assembly and complex formation of poly(diallyldimethylammonium chloride) (PDADMAC) and poly(acrylic acid) (PAA) as a function of pH

The assembly of polyelectrolyte multilayers and the formation of complexes in a solution of poly(diallyldimethylammonium chloride) (PDADMAC) and poly(acrylic acid) (PAA) have been studied as a function of pH. Quartz Crystal Microbalance with Dissipation (QCM-D) in combination with Ellipsometry shows that PAA–PDADMAC multilayers display a supralinear growth pattern at pH 3 with a corresponding change in the frequency response of more than 650 Hz for 17 polyelectrolyte layers. Atomic Force Microscopy (AFM) confirmed the formation of a 200 nm thick film. For pH values higher than 6, assembly is drastically reduced resulting in values below 150 Hz in the QCM-D for the same number of layers. Isothermal Titration Calorimetry (ITC) and Dynamic Light Scattering (DLS) were used to study complex formation. At pH 3, an exothermic heat of complex formation of −2.11 kcal mol−1 was measured. With increasing pH, the heat of complex formation has been seen to decrease. At pH 10, the heat of complex formation tends to be more endothermic and is approximately 0 at pH 13. The addition of urea to PAA at pH 13 resulted in an exothermic heat of complex formation of 1.41 kcal mol−1 during titration with PDADMAC, highlighting the role of hydrogen bonding with water of PAA in governing the interaction between PAA and PDADMAC.
The Perception of Business Risks by SMEs in the Czech Republic

This article aims to find out which business risks determine the perception of the business environment of small and medium-sized enterprises (SME) in the future. 454 SMEs from the Czech Republic participated in the case study by filling in an online questionnaire. Linear regression models were used to verify statistically significant causal relationships between selected indicators of business risks and respondents' perception of the future of business. The results show that selected indicators of the market, financial, personnel, legal and operational risk determine the perceived future of business. Strategic risk indicators do not significantly affect the perceived future of business. The most important indicators: market risk — adequacy of sales of products and services; financial risk — an indicator of the company's financial performance; personnel risk — an indicator of employees' initiative to increase performance; legal risk — an indicator of respondents' ability to understand the basic legal aspects and operational risk — an indicator of the use of company capacities. All the indicators from above have a positive effect on the future perception of the company. Implications for Central European audience: The attitudes of small and medium-sized enterprises represent a certain degree of subjectivity (human factor), which does not always reflect the real position of the enterprise. However, it is the main representatives of SMEs (owners and top managers) who try to manage business risks to have a more positive perception of their future in the business environment in the Czech Republic. The results based on the business environment of the Czech Republic are important not only for the owners of SMEs, but also for state and non-profit institutions dealing with various forms of SME support.
The Effectiveness of Learning Circle Assisted by Geogebra Software Reviewed from Creative Thinking and Visual Thinking Ability of Junior High School Students

The development of creative thinking ability was one of the focuses in learning mathematics. Creative thinking is one of the skills needed in a society, so it is necessary to develop these skills as early as possible. This research aims to describe the effectiveness of learning circle assisted by Geogebra software reviewed from creative thinking and visual thinking ability of Junior High School students. This research was a quasi-experimental research using pretest-posttest control group design. The population was all grade VIII student of One State Sedayu Junior High School. Sample of this research was selected by purposive sampling technique. Two classes from eight classes were selected. The experimental class was VIII F and the control class was VIII G. The experimental class was taught by using Geogebra software while the control class is by using the conventional one. The instruments used on this research were creative thinking test and visual thinking ability test. The result of this research showed that learning circle assisted by Geogebra software is more effective than conventional method for improving creative thinking and visual thinking ability.
Do firms substitute earnings management methods? The case of the MENA region

The purpose of this paper is to empirically test whether firms substitute accruals-based earnings management with real activities-based earnings management or complement the two methods in the MENA region. Further, this paper seeks to investigate the impact of IFRS adoption on accruals-based earnings management. To test the research hypotheses, this paper employs a panel fixed-effects regression model for a sample of 798 non-financial listed MENA region firms over the period 2008-2015, inclusively. The research findings provide evidence that firms complement accruals-based and real activities-based earnings management methods rather than substituting one earnings management method for the other, which suggests that MENA firms conduct both methods concurrently to achieve earnings targets and are not constrained by the relative costs of employing a particular method. Furthermore, a significant positive association between GDP growth and accruals-based earnings management is found, which provides evidence that economic growth leads to a greater degree of accruals-based earnings management behavior in MENA region firms.
Controlling Cucumber Powdery Mildew using Cow Milk and Whey under Greenhouse Conditions

The role of raw cow's milk and whey (40 and 50% dilution in water) and number of sprays against cucumber powdery mildew caused by Sphaerotheca fuliginea was studied in greenhouse experiments during 2017/18 and 2018/19. As a result of number of sprays, the disease severity percentage and area under the disease progress curve (AUDPC) were affected by the number of sprays with raw milk and whey. The number of sprays played an important role in controlling powdery mildew, and significant differences have occurred among all applied sprays. Four sprays with intervals of one week was the effective treatment in reducing disease severity, AUDPC values, compared to other treatments, i.e., two and three sprays in comparison to the fungicide as well as a control treatment. Additionally, treated plants showed a significant increase in plant growth and yield parameters in case of spraying four times. Also, the activity of defense-related enzymes (catalase, peroxidase, and polyphenoloxidase) and amino acid proline was high in response to increasing the number of sprays at four times compared with untreated plants. Light and scanning electron microscopic observations showed a clear change in the morphology of S. fuliginea spores, in addition to hyphae degradation and loss the vitality of conidia as well as rupturing the content of conidia. The results obtained also indicated that cow's milk and whey dilution effectively reduced the powdery mildew signs and symptoms on infected cucumber plants at 50% with the four sprays treatment being the most effective treatment.
Phenotypic characterization of sheep populations in Tahtay Maichew district, Northern Ethiopia

Eighteen quantitative measurements and fourteen qualitative characteristics taken from 306 adult sheep (57 rams and 249 ewes) were used to characterize sheep populations of district, Ethiopia. Most traits showed significant variation by zone, sex and age groups with higher values generally recorded for rams as compared to ewes. Middle age group animals displayed highest values for several traits, reflecting the optimal production age. zone affected ewes more than rams. The highland sheep height at withers, widest shoulder points and longest hair, indicative of adaptation to their environment. Qualitative characteristics of the studied sheep populations such as tail shape, plain coat color pattern, skin, hairy fiber and the absence of horn, toggle, ruff and beard suggest that they constitute a previously sheep breed. Tan coat color differentiated high and midland sheep from lowland sheep where white and brown colors were dominant. Canon bone length, height at withers and tail length were the three most important variables used in discriminating the sheep populations. On average 66% of the animals could be classified into their respective zone. Our data suggest that highland sheep populations are distantly related to lowland sheep, while midland sheep are more closely related to lowland sheep. It can be concluded that breeding programs specific to each zone need to be designed for sustainable utilization and conservation of the studied sheep populations. Furthermore, molecular based studies might allow further characterization of Ethiopian sheep breeds.
Revisiting the Dividend and Investment Puzzle: An International Review using US Corporate Governance Data

ARTICLE DETAILS ABSTRACT History Revised format: November 2020 Available Online: December 2020 This explanatory comparative review uses pooled regression, weighted least squares and GLS panel analysis on 943 listed US firms (2005-2009), while examining the effect of corporate governance (good and questionable), profitability and sales revenue on dividends and investment, seeking to examine the different aspects of the dividend and investment puzzle. After rigorous robust scrutiny, the research empirically endorses the claim that Corporate governance pursue investment decision, while curbing dividend payout, profoundly by questionable corporate governance; cash dividends are seldom given in the US. Sales Revenue (and the firm’s value) boost investments, while its positive influence on dividends is insignificant. All other tactics impede Dividend policy, most profoundly by the firm’s value. Taxable income impedes investment. On the other hand, the firm’s value and sales revenue do significantly influence corporate investment decisions, as postulated by the pecking order, capital structure substitution and residual theories. The empirical results reveal the latent capitalization/expensing ploy used by listed firms. Results suggest that US firms prefer investing funds generated from sales revenue, while expensing off tax deductible profits, thus benefiting from both the virtues of capital investment and expensing. Tax implication as well as the fallacy of dividend avoidance is also examined, apart from recommending policy for regulatory authorities as well as governors (board of directors) of firms to pursue.
Optimization of Tensile-Shear Strength in the Dissimilar Joint of Zn-Coated Steel and Low Carbon Steel

The present study features analytical and experimental results of optimizing resistance spot welding performed using a pneumatic force system (PFS). The optimization was performed to join SECC-AF (JIS G 3313) galvanized steel material with SPCC-SD low carbon steel. The SECC-AF is an SPCC-SD (JIS G 3141) sheet plate coated with zinc (Zn) with a thickness of about 2.5 microns. The zinc coating on the metal surface causes its weldability to decrease. This study aims to obtain the highest tensile-shear strength test results from the combination of the specified resistance spot welding parameters. The research method used the Taguchi method using four variables and a combination of experimental levels. The experimental levels are 2-levels for the first parameter and 3-levels for other parameters. The Taguchi optimization experimental results achieved the highest tensile-shear strength at 5049.64 N. It properly worked at 22 squeeze time cycles, 25 kA of welding current, and 0.6-second welding time and 12 holding-time cycles. The S/N ratio analysis found that the welding current had the most significant effect, followed by welding time, squeeze time, and holding time. The delta S/N ratio values were 1.05, 0.67, 0.57 and 0.29, respectively.
NIST Update: ISAP v2.0

Isap was designed with a focus on robustness against implementation attacks including both side-channel and fault attacks. In particular, special care has been taken when designing the mode so that implementations of Isap without any primitive-level countermeasures provide already a higher baseline with respect to protection against side-channel and fault attacks compared to most other authenticated encryption schemes including CCM [22] and GCM [23]. Hence, Isap is of particular interest for all applications where robustness against side-channel and fault attacks is crucial, including various IoT applications, firmware updates of devices, various NFC and smartcard applications, bitstream encryption of FPGAs, etc. In the following, we outline Isap’s protection claims against implementation attacks.