Retinal degenerative diseases : laboratory and therapeutic investigations

Basic Science Underlying Retinal Degeneration. - Analysis of Genes Differentially Expressed During Retinal Degeneration in Three Mouse Models. - Regulation of Angiogenesis by Macrophages. - Protein Kinase C Regulates Rod Photoreceptor Differentiation Through Modulation of STAT3 Signaling. - Pigment Epithelium-derived Factor Receptor (PEDF-R): A Plasma Membrane-linked Phospholipase with PEDF Binding Affinity. - The Function of Oligomerization-Incompetent RDS in Rods. - The Association Between Telomere Length and Sensitivity to Apoptosis of HUVEC. - Photoreceptor Guanylate Cyclases and cGMP Phosphodiesterases in Zebrafish. - RDS in Cones Does Not Interact with the Beta Subunit of the Cyclic Nucleotide Gated Channel. - Increased Expression of TGF-? 1 and Smad 4 on Oxygen-Induced Retinopathy in Neonatal Mice. - ZBED4, A Novel Retinal Protein Expressed in Cones and Muller Cells. - Tubby-Like Protein 1 (Tulp1) Is Required for Normal Photoreceptor Synaptic Development. - Growth-Associated Protein43 (GAP43) Is a Biochemical Marker for the Whole Period of Fish Optic Nerve Regeneration. - Multiprotein Complexes of Retinitis Pigmentosa GTPase Regulator (RPGR), a Ciliary Protein Mutated in X-Linked Retinitis Pigmentosa (XLRP). - Misfolded Proteins and Retinal Dystrophies. - Neural Retina and MerTK-Independent Apical Polarity of ? v? 5 Integrin Receptors in the Retinal Pigment Epithelium. - Mertk in Daily Retinal Phagocytosis: A History in the Making. - The Interphotoreceptor Retinoid Binding (IRBP) Is Essential for Normal Retinoid Processing in Cone Photoreceptors. - Aseptic Injury to Epithelial Cells Alters Cell Surface Complement Regulation in a Tissue Specific Fashion. - Role of Metalloproteases in Retinal Degeneration Induced by Violet and Blue Light. - Mitochondrial Decay and Impairment of Antioxidant Defenses in Aging RPE Cells. - Ciliary Transport of Opsin. - Effect of Hesperidin on Expression of Inducible Nitric Oxide Synthase in Cultured Rabbit Retinal Pigment Epithelial Cells. - Profiling MicroRNAs Differentially Expressed in Rabbit Retina. - Unexpected Transcriptional Activity of the Human VMD2 Promoter in Retinal Development. - Microarray Analysis of Hyperoxia Stressed Mouse Retina: Differential Gene Expression in the Inferior and Superior Region. - Photoreceptor Sensory Cilia and Inherited Retinal Degeneration. - Role of Elovl4 Protein in the Biosynthesis of Docosahexaenoic Acid. - Molecular Genetics and Candidate Genes. - Molecular Pathogenesis of Achromatopsia Associated with Mutations in the Cone Cyclic Nucleotide-Gated Channel CNGA3 Subunit. - Mutation Spectra in Autosomal Dominant and Recessive Retinitis Pigmentosa in Northern Sweden. - 1 Rhodopsin Mutations in Congenital Night Blindness. - GCAP1 Mutations Associated with Autosomal Dominant Cone Dystrophy. - Genotypic Analysis of X-linked Retinoschisis in Western Australia. - Mutation Frequency of IMPDH1 Gene of Han Population in Ganzhou City. - Diagnostic, Clinical, Cytopathological and Physiologic Aspects of Retinal Degeneration. - Reversible and Size-Selective Opening of the Inner Blood-Retina Barrier: A Novel Therapeutic Strategy. - Spectral Domain Optical Coherence Tomography and Adaptive Optics: Imaging Photoreceptor Layer Morphology to Interpret Preclinical Phenotypes. - Pharmacological Manipulation of Rhodopsin Retinitis Pigmentosa. - Targeted High-Throughput DNA Sequencing for Gene Discovery in Retinitis Pigmentosa. - Advances in Imaging of Stargardt Disease. - Protamine Sulfate Downregulates Vascular Endothelial Growth Factor (VEGF) Expression and Inhibits VEGF and Its Receptor Binding in Vitro. - Computer-Assisted Semi-Quantitative Analysis of Mouse Choroidal Density. - Thioredoxins 1 and 2 Protect Retinal Ganglion Cells from Pharmacologically Induced Oxidative Stress, Optic Nerve Transection and Ocular Hypertension. - Near-Infrared Light Protect the Photoreceptor from Light-Induced Damage in Rats. - BDNF Improves the Efficacy ERG Amplitude Maintenance by Transplantation of Retinal Stem Cells in RCS Rats. - The Role of Purinergic Receptors in Retinal Function and Disease. - Macular Degeneration. - Fundus Autofluorescence Imaging in Age-Related Macular Degeneration and Geographic Atrophy. - Endoplasmic Reticulum Stress as a Primary Pathogenic Mechanism Leading to Age-Related Macular Degeneration. - Proteomic and Genomic Biomarkers for Age-Related Macular Degeneration. - Impaired Intracellular Signaling May Allow Up-Regulation of CTGF-Synthesis and Secondary Peri-Retinal Fibrosis in Human Retinal Pigment Epithelial Cells from Patients with Age-Related Macular Degeneration. - PPAR Nuclear Receptors and Altered RPE Lipid Metabolism in Age-Related Macular Degeneration. - The Pathophysiology of Cigarette Smoking and Age-Related Macular Degeneration. - Oxidative Stress and the Ubiquitin Proteolytic System in Age-Related Macular Degeneration. - Slit-Robo Signaling in Ocular Angiogenesis. - Animal Models of Retinal Degeneration. - Evaluation of Retinal Degeneration in P27KIP1 Null Mouse. - Differences in Photoreceptor Sensitivity to Oxygen Stress Between Long Evans and Sprague-Dawley Rats. - Retinal Degeneration in a Rat Model of Smith-Lemli-Opitz Syndrome: Thinking Beyond Cholesterol Deficiency. - Do Calcium Channel Blockers Rescue Dying Photoreceptors in the Pde6b rd1 Mouse? - Effect of PBNA on the NO Content and NOS Activity in Ischemia/Reperfusion Injury in the Rat Retina. - Recent Insights into the Mechanisms Underlying Light-Dependent Retinal Degeneration from X. Laevis Models of Retinitis Pigmentosa. - A Hypoplastic Retinal Lamination in the Purpurin Knock Down Embryo in Zebrafish. - Functional Changes in Inner Retinal Neurons in Animal Models of Photoreceptor Degeneration. - Photoreceptor Cell Degeneration in Abcr -/- Mice. - Investigating the Mechanism of Disease in the RP10 Form of Retinitis Pigmentosa. - Congenital Stationary Night Blindness in Mice - A Tale of Two Cacna1f Mutants. - Protection of Photoreceptors in a Mouse Model of RP10. - Correlation Between Tissue Docosahexaenoic Acid Levels and Susceptibility to Light-Induced Retinal Degeneration. - Activation of Muller Cells Occurs During Retinal Degeneration in RCS Rats. - Effect of 3? -Daidzein Sulfonic Sodium on the Anti-oxidation of Retinal Ischemia/Reperfusion Injury in Rats. - Structural and Functional Phenotyping in the Cone-Specific Photoreceptor Function Loss 1 (cpfl1) Mouse Mutant - A Model of Cone Dystrophies. - The Differential Role of Jak/Stat Signaling in Retinal Degeneration. - Neuroprotection and Gene Therapy. - Gene Therapy in the Retinal Degeneration Slow Model of Retinitis Pigmentosa. - PEDF Promotes Retinal Neurosphere Formation and Expansion In Vitro. - A Multi-Stage Color Model Revisited: Implications for a Gene Therapy Cure for Red-Green Colorblindness. - Achromatopsia as a Potential Candidate for Gene Therapy. - Function and Mechanism of CNTF/LIF Signaling in Retinogenesis. - gp130 Activation in Muller Cells is Not Essential for Photoreceptor Protection from Light Damage. - Neuroprotectin D1 Modulates the Induction of Pro-Inflammatory Signaling and Promotes Retinal Pigment Epithelial Cell Survival DuringOxidative Stress. - Adeno-Associated Virus Serotype-9 Mediated Retinal Outer Plexiform Layer Transduction is Mainly Through the Photoreceptors.