Miracle-dz/UniFAR-FTUs huggingface dataset:
Oxytocin in Behavior Therapy: Enhancing the Acceptance of Body Contact between Mother and Children by Application of Oxytocin – a Case Study

nicht mehr traumabezo-gen war, sondern ein Rest, der auf der Basis klassischer Konditionierung weiterbestand, ohne irgendeine aktuelle Funktion. Der Effekt des Oxytocins trat fast sofort nach Anwendung ein und steigerte die Toleranz für Körperkontakt von 10 s (vor der Intervention) auf eine Stunde und mehr (mit Oxytocin). Die Patientin beschrieb den Effekt als angenehm und entspannend. Nach 3 Wochen wurde der Einsatz von Oxytocin beendet, und wie vor-ausgesagt steigerte sich die Akzeptanz von Körperkontakt kontinuierlich weiter und blieb mindestens 22 Mona-te stabil. Schlussfolgerungen: Dies zeigt, dass der Einsatz von Oxytocin die Mutter-Kind-Interaktion schnell und nachhaltig verbessern kann. Weitere Studien sollten untersuchen, ob der Einsatz von Oxytocin eine effektive Möglichkeit sein könnte, physischem Missbrauch von Kindern vorzubeugen und die Eltern-Kind-Beziehung zu verbessern.
Does School Lunch Fill the “Snap Gap” at the End of the Month?

This article investigates the relationship between the timing of Supplemental Nutrition Assistance Program (SNAP) benefit payments and participation in school lunch and breakfast using the National Household Food Acquisition and Purchase Survey. An event study approach examines participation over the five‐day window before and after the SNAP payment. We find that school lunch participation decreases by 17–23 percentage points immediately after the SNAP payment among 11–18 year olds while breakfast drops by 19–36 percentage points. The decline begins the day prior to payment. We find no effects for 5–10 year olds. Models examining participation over the full SNAP month using individual fixed effects yield similar findings. Among teenagers, participation in school lunch and breakfast decline in the first two weeks of the SNAP month, increasing afterward. Non‐school meals show the opposite pattern. Overall, results indicate SNAP households rely more on school lunch and breakfast toward the end of the SNAP month.
TQM and performance appraisal: complementary or incompatible? Abstract Despite the scholarly interest in performance management as a prime determinant of the effectiveness of enterprise process improvement methods such as total quality management (TQM)

Despite the scholarly interest in performance management as a prime determinant of the effectiveness of enterprise process improvement methods such as total quality management (TQM) and its derivatives, few empirical studies have explicitly explored the practice of performance management systems in TQM-focused organisations. In order to redress this imbalance, this study aims to describe how organisational and managerial forces result in performance management systems failing to embrace the core values and principles of process improvement methods such as TQM. Using a qualitative study of six large UK-based automobile and auto parts manufacturers, our results illustrate how manager-controlled, individual-focused, past-oriented, long-cycle, and narrowly defined performance appraisal (PA) systems can intervene to underline the ultimate potential of TQM. The paper concludes with the discussion of implications for theory and practice of TQM and human resource performance management.
Automatic synthesis of reconfigurable instruction set accelerators

• A submitted manuscript is the author's version of the article upon submission and before peer-review. There can be important differences between the submitted version and the official published version of record. People interested in the research are advised to contact the author for the final version of the publication, or visit the DOI to the publisher's website. • The final author version and the galley proof are versions of the publication after peer review. • The final published version features the final layout of the paper including the volume, issue and page numbers.
TOURISTS’ PERSPECTIVES OF MARINE ECOSYSTEM SERVICES AS THE FIRST STAGE OF PARTICIPATORY MODELING IN THE SOUTH COAST OF SAO PAULO

Although the tourism sector is tightly connected to environmental issues, it is one of the least prepared to deal with changes in environmental conditions, especially with climate changes. Monitoring environmental quality in consolidated coastal destinations becomes fundamental to face the complexity involving marine and coastal ecosystems and tourist afflux. The assessment of stakeholders’ perspective of the benefits these ecosystems provide can be a first step towards the use of modeling approaches to assist coastal planning. As part of a modeling process, this work explores tourists’ perspective of marine ecosystem services, conditions considered in destination choice, and their reaction to changes in seawater quality through a semi structured survey at the municipality of Ubatuba, Sao Paulo, Brazil. The results show that the most perceived ecosystem services are cultural (recreational and aesthetic) and provision (fishery). Also, they identified water quality as the most important aspect of beach selection, which was considered a factor of destination choice. In addition, sewage and solid waste were the most significant factors perceived as responsible for altering seawater quality. The results reinforce the potential of including tourists’ point of view to subsidize the design of socio-ecological modeling approaches.
PROPERTIES OF NONUNIFORM RANDOM GRAPH MODELS

This is a survey on network models designed to produce graphs that resemble natural networks. Unlike artificially generated networks, natural networks are graphs that have been constructed based on some phenomenon or object of the real world. The report includes two extensive case studies of natural networks that emerge from engineering applications: the network model of the router-level Internet and the Web graph, which is a model of the World Wide Web. Several different models for generating such networks are discussed. After a brief summary of basic graph theory, the traditional model of uniform random graphs is presented with generalizations. Two recent models of natural graphs are discussed in detail: the small-world networks that capture characteristics of social networks, and the scale-free networks that imitate real-world communication networks. Several variations of both models are presented, including some deterministic models. After studying the mathematical descriptions of the models and some analytically derived properties, experimental work is documented. Properties of different network models are examined by software implementations of the model descriptions. In addition to calculating some graph theoretical metrics, the algorithmic implications of the network models are studied through the running times of an algorithm that determines the order of a maximum clique in a given graph. This report also contains a brief review on clustering algorithms for graphs. The goal of clustering is to identify semantically meaningful entities from arbitrary graphs. The traditional approach to clustering is to split the given graph into clusters starting from the entire graph. This does not scale well to very large graphs, and therefore algorithms that employ local search are of interest. In this work, heuristic methods for finding clusters from large and possibly unknown graphs are proposed.
Running Head: DEVELOPING IDENTITY LEADERSHIP IN DISABILITY SPORT

Based on social identity principles we explore the efficacy of a leadership intervention in elite 13 disability sport. A two-year longitudinal design involved an elite male disability soccer team 14 that prepared for a World Championship in Year 1 and then reformed for Paralympic 15 competition in Year 2. Athlete data indicated marginal to significant increases from baseline 16 to intervention phases in social identification, identity leadership displayed by staff, and 17 hours practice completed away from training camps, but no significant change in 18 mobilization of effort (in Year 1 and 2). We discuss the applied implications, study 19 limitations, and opportunities for future researchers. 20
Polygenic Risk for Externalizing Disorders: Gene-by-Development and Gene-by-Environment Effects in Adolescents and Young Adults

In this project, we aimed to bring large-scale gene-identification findings into a developmental psychopathology framework. Using a family-based sample, we tested whether polygenic scores for externalizing disorders—based on single nucleotide polymorphism weights derived from genome-wide association study results in adults ( n = 1,249)— predicted externalizing disorders, subclinical externalizing behavior, and impulsivity-related traits among adolescents ( n = 248) and young adults ( n = 207) and whether parenting and peer factors in adolescence moderated polygenic risk to predict externalizing disorders. Polygenic scores predicted externalizing disorders in adolescents and young adults, even after we controlled for parental externalizing-disorder history. Polygenic scores also predicted subclinical externalizing behavior and impulsivity traits in the adolescents and young adults. Adolescent parental monitoring and peer substance use moderated polygenic scores to predict externalizing disorders. This illustrates how state-of-the-science genetics can be integrated with psychological science to identify how genetic risk contributes to the development of psychopathology.
pp60 c-Src Kinase Mediates Growth Effects of the Full-Length Precursor Progastrin 1–80 Peptide on Rat Intestinal Epithelial Cells, in Vitro

Growth factor effects of precursor forms of gastrins have be- come evident in recent years. However, intracellular path-ways that mediate growth effects of the precursor molecules are not known. In previous studies, we reported an increase in Tyr phosphorylation of pp60 c-Src in intestinal epithelial cells (IEC) in response to the fully processed form of gastrin [gastrin 1–17 (G17)]. We have now examined whether c-Src ki- nase is similarly phosphorylated and activated in response to the full-length precursor molecule, progastrin (PG) 1–80, (re- combinant human PG) in IEC cells. We found a significant increase in pp60 c-Src kinase activity in response to both G17 and PG (0.1–1.0 n M ), suggesting that growth effects of both the precursor and fully processed gastrin molecules may be me- diated via similar pathways. On the other hand, pp62 c-Yes was not phosphorylated or activated in response to either G17 or PG. To examine whether c-Src kinase mediates proliferative effects of PG, IEC cells were microinjected with anti-Src-IgG and 3 H-thymidine ( 3 H-Tdr) uptake of the cells measured. Con- trol cells received nonimmune IgG. The 3 H-Tdr uptake of cells stimulated with 1.0 n M PG was significantly reduced in cells microinjected with anti-c-Src-IgG; control IgG had no effect. In cells stimulated with 1.0% fetal calf serum, microinjection with c-Src-IgG had no effect on 3 H-Tdr uptake. The specificity of the effect was further confirmed by blocking the inhibitory effect of anti-c-Src-IgG with antigenic Src peptide. These results suggest that activation of c-Src kinase likely represents a critical step in mediating proliferative effects of both the precursor and fully processed forms of gastrins on IEC. ( En- docrinology 144: 201–211, 2003) c-Src
The relationships among psychological determinants, risk behaviour, and road crashes: implications for RSE programmes

Road safety education (RSE) assumes that psychological determinants predict risk behaviour, and subsequently that risk behaviour predicts crash involvement. This study examined the validity of this assumption, by analysing these relationships in two age groups of teen cyclists and pedestrians: a younger age group (12 and 13 years old: n = 1372) and an older age group (14 through 16 years old: n = 938). A questionnaire was administered at school during regular class consisting of items on demographics, on risk behaviour based on the Generic Error Modelling System (GEMS), on psychological determinants targeted in RSE programmes, and on crash involvement. For both age groups, the results indicated that risk behaviour predicted crashes (young group R 2 = .05; older group R 2 = .11). Path analyses also confirmed that risk behaviour could be predicted from the psychological determinants, sharing respectively 44% of the variance in the younger age group and 34% in the older group. In conclusion, these results confirm the RSE assumption that psychological determinants are associated with a higher frequency of risk behaviours and that the latter are again associated with higher crash frequencies. Just as in earlier studies on adolescent risk behaviour, the GEMS based distinction between errors and violations was not confirmed, suggesting that this distinction – derived from studies on adult car drivers – may not apply to young adolescent cyclists and pedestrians. (a) violations, errors, play and lack of of risk (H1), (b) these risk behaviours and (c) the psychological determinants risk behaviour and To assess the generalizability of
RRTM_A_274518 119..128

1Department of Internal Medicine, School of Medicine, Texas Tech University Health Sciences Center, Lubbock, TX 79430, USA; 2Center for Tropical Medicine and Infectious Diseases, School of Medicine, Texas Tech University Health Sciences Center, Lubbock, TX 79430, USA Abstract: Schistosomiasis is a neglected tropical disease inflicting significant morbidity in humans worldwide. The disease is caused by infections with a parasitic trematode belonging to the genus Schistosoma. Over 250 million people are currently infected globally, with an estimated disability-adjusted life-years of 1.9 million attributed to the disease. Current understanding, based on several immunological studies using experimental and human models of schistosomiasis, reveals that complex immune mechanisms play off each other in the acquisition of immune resistance to infection/reinfection. Nevertheless, the precise characteristics of these responses, the specific antigens against which they are elicited, and how these responses are intricately regulated are still being investigated. What is apparent is that immunity to schistosome infections develops slowly and over a prolonged period of time, augmented by the death of adult worms occurring naturally or by praziquantel therapy. In this review, aspects of immunity to schistosomiasis, host–parasite interactions and their impact on schistosomiasis vaccine development are discussed.
Mathematical Communication Ability Assessed By Student Self- efficacy In Learning The Two Stay Two Stray (TSTS) Model on Ability of Process Approach

_______________________________________________________________ This study aims to determine the ability of mathematical communication in terms of students self-efficacy in learning type two stay two stray (TSTS) cooperative approaches with process skills. The method used in this research is mixed method with concurrent embedded design. This research was conducted in class VII SMPN 40 Semarang in the academic year 2017/2018 with class VII F as an experimental class subjected to cooperative learning model type TSTS approached by process skills and class VII G as a control class subjected to the Problem Based Learning model. Data is collected by tests, questionnaires, observation sheets and interviews. Subject taking techniques based on self-efficacy were taken 2 subjects for each category by random sampling . The results showed that the description of mathematical communication skills in terms of students' self-efficacy varied. This is shown from 7 students with high self-efficacy categories obtained mathematical communication skills in the form of 5 students in the high category and 2 students in the moderate category, from 21 students in the category of self-efficacy being obtained mathematical communication skills results in the form of 8 students in
PREVALENCE AND ASSOCIATION OF MICROALBUMINURIA IN HYPERTENSIVE PATIENTS WITH OR WITHOUT TYPE 2 DIABETES.

events - both in with with ABSTRACT Background : Microalbuminuria develops from progressive, subclinical, structural and functional changes within the kidney and represents a sensitive marker of early renal disease. Microalbuminuria is typically defined as a 24-h urinary albumin excretion rate (UAE) of 30-300mg (20-200 µ g/min) or urinary albumin: creatinine ratio (UACR) of 2.5-30mg/mmol in men, 3.5-30mg/mmol in women. The aim of this study was to determine prevalence and association of urinary microalbuminuria (MAU) in patients with hypertension and/or type 2 diabetes mellitus (DM). Methods: The study was a prospective, cross sectional and observational study conducted on patients with hypertension with or without type 2 diabetes mellitus of KIMS Hospital and Research Centre, Bangalore. The main outcome measures were the prevalence of MAU as assessed by fully automated immune turbidometry method and blood pressure. Demographic variables, presence of co morbidities, use of cardiovascular and antidiabetic drugs and biochemical variables were also analyzed. Results : A total of 150 patients (50 with hypertension, 50 with both DM and hypertension and 50 controls), 66%woman, were included in the study. Overall prevalence of MAU was 86% in patients with DM and hypertension, 76% in patients with hypertension. In multivariate analysis, predictors for MAU were the presence of DM or hypertension, HbA1c, male, age, blood pressure, and total cholesterol and triglyceride TG. Conclusion : Hypertension and DM are the established risk factors for cardiovascular disease and renal disease. Routine MAU screening by turbidometry method would help identify individuals at risk and increase awareness of kidney disease and TOD.
Health and Well-Being in Emerging Adults’ Same-Sex Relationships: Critical Questions and Directions for Research in Developmental Science

Researchers have yet to account for the potentially unique experiences of emerging adults who are in or seeking to be in a relationship with a same-sex romantic partner. This article articulates an agenda for research focused on better understanding and addressing the health and well-being of emerging adults in or pursuing same-sex romantic relationships. We provide a general summary of what is known about health and well-being in same-sex relationships, followed by an overview of the current and changing social climate surrounding same-sex relationships. We point out how recent historical changes present sexual minority emerging adults with unique relational benefits and challenges that have not been examined within the social and health sciences. We conclude by proposing a set of research questions to help develop knowledge needed to improve the health and well-being of emerging adults in or pursuing same-sex relationships.
Deep anterior lamellar keratoplasty for keratoconus: Elements for success

Advanced keratoconus may require keratoplasty when the patient can no longer achieve functional vision with glasses and contact lenses. Deep anterior lamellar keratoplasty (DALK) has become the surgical treatment of choice due to its undisputed advantages over penetrating keratoplasty including the reduced risk of intraoperative complications, the absence of endothelial immune rejection, and the longer graft survival. Albeit “big-bubble” DALK still represents the most popular surgical method, several modifications have been developed over the years. This allowed standardization of the technique, with improved success rates and clinical outcomes. This review presents an overview on the literature on DALK surgery for keratoconus. We discuss state-of-the art surgical techniques, current evidence on the clinical outcomes and complications as well as possible future directions.
Antioxidant and antiproliferative activities of n-hexane extract and its fractions from Blumea balsamifera L. leaves

Blumea balsamifera is a plant species that has been popularly used to treat a broad spectrum of diseases. In efforts of tackling the increasing threat of cancers, B. balsamifera has been studied for its anticancer potentials. Hence, through this research, we aimed to evaluate the antioxidant and antiproliferative activities of n-hexane extract from B. balsamifera L. leaves along with its fractionation products. After the n-hexane extract has been obtained, the sample was column chromatographed using gradient elution with n-hexane:ethyl acetate solvent. All the isolation protocols produced 1 n-hexane extract and 10 different fractions (fractions 1–10). Antioxidant and antiproliferative effects of the samples were assessed based on 2,2-diphenyl-1-picrylhydrazyl and brine shrimp lethality test assay, respectively. None of the samples have a strong antioxidant level because all samples yielded IC50 of more than 100 ppm – the best of them was fraction 8 with IC50 = 113.716 ppm. On contrary, most of the samples were observed to have a potent antiproliferative effect, especially fraction 8 with LC50 = 2.00 ppm. Taken altogether, fraction 8 from the n-hexane extract of B. balsamifera L. leaves is the most potential candidate for proliferative disease therapy, where further studies confirming the results are required.
A randomized, open-label, multicentered parallel-group clinical study to evaluate the efficacy and safety of Joint Core™ compared to Jointace DN™ in osteoarthritis patients

Background: Osteoarthritis (OA) is one of the most common musculoskeletal diseases worldwide, with pain, joint stiffness, fatigue associated with disability, and loss of physical activity. There is a need for an effective and safer alternative medication for the management of OA knee in elderly patients as the current medications possess severe risks to the patient compromising the quality of life. Methodology: The study design and setting were phase 3, randomized, open-label, multicentered, active-controlled parallel-group interventional trial conducted at secondary care centers in Puducherry. Fifty patients (50) patients with OA knee were enrolled as per study criteria and randomized to receive Joint Core™ and Jointace DN™ for 12 weeks. The outcomes were assessed using various pain scales and subscales, Short-Form Health-12 (SF-12) questionnaire, and inflammatory markers. The data obtained at baseline and weeks 4, 8, and 12 were compared and statistically analyzed. Results: Joint Core™ showed continuous reduction in the Visual Analog Scale pain scores at 4, 8, and 12 weeks and improvement in Western Ontario and McMaster Universities OA Index subscale and pain global assessment scales and good response rate in the Outcome Measures for Rheumatology Committee and OA Research Society International Standing Committee for Clinical Trials Response Criteria Initiative scores proving it to be efficacious in the treatment of OA knee compared to Jointace DN™. The safety assessed showed that Joint Core™ produces minimal gastrointestinal side effects and does not affect any organs as assessed by the laboratory parameters. Conclusion: Joint Core™ is effective and safe in the treatment of OA knee when compared to its comparator Jointace DN™. Joint Core™ can be an alternative treatment option in the patients with OA knee who are intolerant to diacerein-based combinations available to treat OA.