Miracle-dz/UniFAR-FTUs huggingface dataset:
THE EFFECT OF THE TRAINING PROGRAM ABOUT MANAGEMENT OF ELDERS’ COMMON PROBLEMS ON THE LEVEL OF JOB STRESS IN CAREGIVERS OF NURSING HOMES

Background and Objective: With increasing older people population, the need to provide health care services in nursing homes is increasing. The aim of this study was to determine the effect of an educational program about the management of common problems in old age on the level of job stress in the caregivers of Golestan province nursing homes. Material and Methods: This pre-experimental study was conducted on all 24 caregivers (11 males and 13 females) working in the nursing homes of Golestan province. The valid and reliable instruments were a researcher-made questionnaire to evaluate the knowledge and Osipow's job stress questionnaire, the intervention was an educational package to increase their knowledge and skills about the management of old age problems. The questionnaires were completed before, immediately after, one month and three months after the training. The data was analyzed by analysis variance, Pearson correlation, independent t-test and paired t-test. Results: With increasing the knowledge of the caregivers, a significant reduction in job stress scores (p<0.001) was found after three months. Two components of job stress including overload (p<0.001) and insufficiency (p=0.002) showed significant decreases after three months compared to the mean scores before training. Conclusion: Due to The effect of training on stress reduction, providing comprehensive training programs for caregivers may lead to higher quality services and health promotion for both elders and their caregivers.
Efficacy and Tolerance of Fludarabine and Cyclophosphamide (FC) Combination Regimen in advance stage of Chronic Lymphocytic Leukemia

Background: based on data suggesting synergistic activity of fludarabine (F) and cyclophosphamide (C) combination therapy. This study was conducted to assess the efficacy and tolerability of this combination chemotherapy in Iraqi adult patients with advanced chronic lymphocytic leukemia (CLL), reflected by better response rate, treatment free survival and overall survival benefit. Patient and Methods: A prospective study carried out in Baghdad teaching hospital and national hematology center in Baghdad between February 2005 and fabruary 2009. It included 64 Iraqi patients aged between 39-77 years old with advanced stage CLL. Written informed consent wasobtained from all patients prior to start of therapy. They received FC combination therapy (fludarabine 25 mg/ m2 plus cyclophosphamide 250mg/ m2 for 3 days intravenously, repeated every 28 days). Treatment was administered for 6 courses. Results: Out of 64 CLL patients with Binet stage B&C who were included in this study, 41(64.1%) patients were male and 23 (35.9%) patients were females (M:F ratio1.7:1) with median time of follow-up 26 months. median age was 59.9 years. Forty- eight (75%) patients were previously untreated, of them 22 (45.8%) patients were stage B and 26 (45.1%) patients were stage C while the other 16 (25%) patients with CLL were previously treated with an alkylating agents, of them 7(43.7%) of stage B and 9 (56.2%) with stage C. This combination chemotherapy resulted in 39.1% complete remission and 39.1% partial remission. The two years median treatment-free survival was 90% with the median duration of response was 18 months. there was a significant difference (p<0.005) between the different Binet stage group (C&B) and degree of response, with better response rate in those with stage C than those with stage B. the overall response rate was 88.5%, 65.5% for stage C and B respectively.The major toxicity (grade 3-4) were nausea and vomiting while the myelosupression of grade 1&2 for leucopenia and neutropenia occur in 19%, 14% respectively. Conclusion: Fludarabine and cyclophosphamide combination regimen is an effective therapy for patients with advance CLL with high response and complete remission rate in those untreated and previously treated CLL patients, with good tolerability to this combination.
4-Bromo-N-(4-methoxy-2-nitrophenyl)benzamide

In the title compound, C14H11BrN2O4, the amide segment makes dihedral angles of 23.4 (2) and 20.5 (2)° with the benzene rings, while the dihedral angle between the bezene rings is 2.90 (8)°. The nitro and methoxy groups are almost coplanar with their bound benzene ring, with the r.m.s. deviation for the 11 non-H atoms being 0.0265 (1) Å. An intramolecular N—H⋯O hydrogen bond generates an S(6) ring motif. In the crystal, molecules are linked into [2-10] chains by weak C—H⋯O and C—H⋯Br interactions, which form an R 2 2(8) motif between pairs of molecules in the chain. A Br⋯O [3.2018 (12) Å] short contact also occurs.
1-(2-Chloro-5-nitrophenyl)-3-(2,2-dimethylpropionyl)thiourea

With the exception of the C atoms of two of the methyl groups of the tert-butyl substituent, all of the non-H atoms of the title compound, C12H14ClN3O3S, lie on a mirror plane. The 2-chloro-5-nitrophenyl and 2,2-dimethylpropionyl substituents are, respectively, cis and trans relative to the thiocarbonyl S atom across the two C—N bonds. Intramolecular N—H⋯O and C—H⋯S hydrogen bonds form S(6) ring motifs, also in the mirror plane. Despite the presence of two N—H subsituents, no intermolecular hydrogen bonds are observed in the crystal structure. Weak π–π contacts [centroid–centroid distances of 4.2903 (17) Å] involving adjacent aromatic rings link the molecules in a head-to-tail fashion above and below the molecular plane.
(E)-1-(2-Hydroxyphenyl)-3-(3,4,5-trimethoxyphenyl)prop-2-en-1-one

The title compound, C18H18O5, was prepared by the condensation of 2-hydroxyacetophenone with 3,4,5-trimethoxybenzaldehyde. The trimethoxyphenyl and hydroxyphenyl rings of the chalcone system are approximately coplanar.
Lipoprotéines plasmatiques et anorexie mentale. Effet de la réalimentation

Objectifs et methodologie : La frequence de l'hypercholesterolemie dans l'anorexie mentale n'a ete appreciee que sur de petites series. C'est pourquoi nous avons etudie le profil des lipoproteines plasmatiques et son evolution sous realimentation chez 120 patients atteints d'anorexie mentale. Une ultracentrifugation des lipoproteines a ete effectuee avant et sous realimentation. Les resultats ont ete compares a ceux de 2 groupes de sujets apparies pour le sexe et l'âge : un groupe de sujets sains et un groupe de patients ayant d'autres types de denutrition. Resultats : Chez les anorexiques, le cholesterol total etait significativement plus eleve que chez les autres denutris, et plutot plus bas que celui des sujets sains. Il etait superieur a 250 mg/100 ml dans 16 % des cas, mais inferieur a 150 mg/100 ml dans 26 % des cas. Dans 36 % des cas, le cholesterol-LDL etait superieur a 150 mg/100 ml, le plus souvent associe a un cholesterol HDL eleve. Les triglycerides et les TG-VLDL etaient plus eleves chez les anorexiques que chez les sujets sains. Sous realimentation, l'incidence de ces differentes anomalies diminuait. Le cholesterol total, LDL et HDL etaient correles positivement a l'index de masse corporelle et a l'albuminemie, et negativement a la denutrition, aux hormones thyroidiennes et au processus inflammatoire. Conclusion : Dans l'anorexie mentale, l'hypercholesterolemie relative est explicable par l'absence de syndrome inflammatoire. Moins frequente que l'hypocholesterolemie, elle est souvent associee a une elevation du cholesterol HDL et se corrige sous renutrition.
1,5-Dimethyl-2-nitroimino-1,3,5-triazinane

The asymmetric unit of the title compound, C5H11N5O2, contains two independent molecules. The two triazine rings adopt envelope conformations. Intramolecular C—H⋯N and N—H⋯O hydrogen bonds result in the formation of two five- and two six-membered rings which are nearly planar; in addition, they are also nearly coplanar. In the crystal structure, intermolecular N—H⋯N, C—H⋯N and C—H⋯O hydrogen bonds link the molecules.
Correlation of Blood Glucose Level, Glycated Hemoglobin, Total Cholesterol and Triacylglycerol Level in Diabetic Patients Attending Tertiary Care Hospital in Eastern Nepal

Background: Measurement of blood glucose level and glycated hemoglobin (HbA1c) are widely used for long term management of diabetes and its complications. Dyslipidemia, an abnormal level of lipids in blood, is frequently associated with diabetes as a strong risk factor for developing cardiovascular disease, and its control can prevent cardiovascular complications. In this study of diabetic patients, we assessed the blood glucose level, HbA1c and estimated average glucose (eAG) to determine the correlation with lipid profiles specifically the total cholesterol(TC) and triacylglycerol(TAG).
UROLITÍASE OBSTRUTIVA EM BOVINOS NO SEMI-ÁRIDO PARAIBANO

OBSTRUCTIVE UROLITHIASIS IN CATTLE IN PARAIBA’S SEMIARID REGION This study reports three cases of bovine obstructive urolithiasis in Paraiba’s semiarid region. The animals showed depression, dehydration, strangury, abdominal discomfort, and bruxism. One of them had severe ascites and eventually died; the others were able to recover after urethrostomy. Urolithiasis frequently occurs in cattle that are not castrated and eat a highroughage diet. There is a need to carry out more studies that investigate the composition of urinary calculi and its probable causes in order to develop prophylactic measures to control urolithogenic processes.
ACUTE AND CHRONIC REACTIONS TO TRAUMA IN CHILDREN AND ADOLESCENTS

This publication is intended for professionals training or practicing in mental health and not for the general public. The opinions expressed are those of the authors and do not necessarily represent the views of the Editor or IACAPAP. This publication seeks to describe the best treatments and practices based on the scientific evidence available at the time of writing as evaluated by the authors and may change as a result of new research. Readers need to apply this knowledge to patients in accordance with the guidelines and laws of their country of practice. Some medications may not be available in some countries and readers should consult the specific drug information since not all dosages and unwanted effects are mentioned. Organizations, publications and websites are cited or linked to illustrate issues or as a source of further information. This does not mean that authors, the Editor or IACAPAP endorse their content or recommendations, which should be critically assessed by the reader. Websites may also change or cease to exist. ©IACAPAP 2014. This is an open-access publication under the Creative Commons Attribution Non-commercial License. Use, distribution and reproduction in any medium are allowed without prior permission provided the original work is properly cited and the use is non-commercial. Suggested citation: Bui E, Ohye B, Palitz S, Olliac B, Goutaudier N, Raynaud JP, Kounou KB & Stoddard FJ Jr. Acute and chronic reactions to trauma in children and adolescents. In Rey JM (ed), IACAPAP e-Textbook of Child and Adolescent Mental Health. Geneva: International Association for Child and Adolescent Psychiatry and Allied Professions 2014. Eric Bui MD, PhD
Does wearing high-heeled shoe cause hallux valgus? a survey of 1,056 Chinese females

Objective: To determine the prevalence of hallux valgus and its relationship to wearing high-heel shoes in Chinese females. Methods: A total of 1,056 healthy females between the ages of 18 and 65 responded to the self-reported questionnaires. Photographs of each classified hallux valgus condition were given as references and each respondent was asked to rate her foot condition as well as completing a questionnaire. The study took place between June and August 2008 in Hong Kong. Data analysis: Cross-tabulation and frequencies commands were used to compute the incidences of hallux valgus with regard to age, severity of illness, complaints and actions taken by the respondents. A chi-square statistic was used to compare the frequencies of occurrences between younger and older respondents. The relative risk (RR) was calculated in order to understand the probability of having hallux valgus in relation to wearing high-heels and family history. Results: Of the 1,056 respondents, 36.5% indicated having various degree of hallux valgus. 29.5% (n=312) had ‘mild’ condition, 4.8% (n=50) had ‘moderate’ and only 2.2% (n=24) reported ‘severe’ hallux valgus. 5o ‘extreme’ case was reported. Subjects over aged 40 had higher injury prevalence (chi-square=34.4; p<.01) than the young counterparts. 88.8% of those having hallux valgus reported that their family members had history of hallux valgus. 73.2% of them who did not wear high-heels regularly but with family history also had hallux valgus. For those with no family history but often wore high-heels, only 2.8% had hallux valgus. Subjects with family history of hallux valgus would be 26 times (RR=26) as likely as those without family history and often wore high-heeled shoes to develop hallux valgus. Conclusion: Hallux valgus is prevalent in the Chinese females. Wearing high-heels seemed to not be a predisposing factor of hallux valgus in Chinese females; however a family history was a major concern.
The Role of Membrane Lipid Composition on Skeletal Muscle Damage in the Rodent Model of Duchenne Muscular Dystrophy

ii CONTRIBUTIONS . v TABLE OF CONTENTS . vi LIST OF FIGURES . ix LIST OF TABLES . xi CHAPTER 1: INTRODUCTION . 1 Biological membranes . 2 Membrane composition . 2 Membrane lipids . 2 Phospholipids . 3 Glycolipids . 4 Cholesterol . 4 Fatty acids . 6 Membrane proteins . 8 Membrane fluidity . 8 Phospholipid species . 9 Fatty acid characteristics . 9 Cholesterol . 11 Membrane structure protein function relationship . 11 Impact of lipid composition on protein function . 12 Skeletal muscle . 14 Skeletal muscle cell structure . 16 Skeletal muscle fibre types . 19 Skeletal muscle mechanics . 21 Membrane lipid composition in mammalian skeletal muscles . 27 Sarcolemma Functions . 28 Muscular dystrophy . 33 Rodent model of muscular dystrophy, mdx mice . 34 Muscular dystrophy etiology . 35 Chronology of mdx phenotype . 42 Statement of the problem . 60
(4-Methoxyphenyl)(4-methylcyclohexyl)methanone

The title compound, C15H20O2, crystallizes with two independent molecules of similar geometry in the asymmetric unit. The cyclohexyl ring adopts a chair conformation in each molecule. In the crystal, molecules related by translation are linked into chains along the a axis via weak C—H⋯O interactions.
2,3,4,9-Tetrahydro-1H-carbazole

In the title compound, C12H13N, two methylene C atoms of the cyclohexene ring are disordered over two sites with occupancies of 0.591 (10) and 0.409 (10); both disorder components adopt half-chair conformations. The crystal structure is stabilized by intermolecular N—H⋯π and C—H⋯π interactions.
Population Dynamics of Tetranychus urticae Koch (Acarina: Tetranychidae) of Carnation under Protected Conditions

The seasonal incidence data on carnation indicated that mite population was started from 9th SMW (0.45 mite/plant) and there was a gradual increase in population and reach its peak during 27th SMW (34.51/plant) (Standard Meteorological Week). Mite population was fluctuated from 0.45 to 34.51 per plant during October 2008 to September 2009. Correlation studies between weather parameter and T. urticae revealed that the mobile stages of mite had highly significant positive correlation with maximum temperature (r= 0.76177) and minimum temperature (r= 0.35665) whereas, morning and evening relative humidity (RH) had exhibited significant negative correlation with mite population were r= -0.76923 and r= -0.45777, respectively
Moving from teaching older learners to young learners : cases of English language teachers in Turkey

This thesis explores the experiences of four English language teachers in Turkey who moved from teaching in either high schools or language schools to teaching English to young learners. The study follows these teachers in their first year of teaching in primary school, describes the changes they went through in their approach to teaching English, and identifies the influences on these changes. The background to this research was an educational reform which introduced English into the primary curriculum. After this reform, there was a shortage of English teachers at the primary level. A common solution was to recruit English teachers from other levels of the educational system. Three of the participating teachers taught in high school before they moved to teach English in the primary school. One of the participating teachers taught English to adults in a language school before moving to the primary level. The data for the study was generated through systematic interviews with the teachers, as well as regular observations of their classes, over the course of the school year. The interpretation of the data was informed by the existing literature on teaching English to young learners and the literature on teacher change. At the end of the school year, all of the teachers said they would like to continue teaching English in the primary school. In adjusting to teaching children, the teachers mainly focused on developing class management strategies. The teachers did not, however, focus on maximising opportunities for learning the target language. The main influences on the teachers' change were in-service training, textbooks, as well as interaction with and support from colleagues. The research contributes to the debate of how to best facilitate the introduction of English into primary schools, and calls for further research into teacher development in the context of such curricular reforms.
3‐(3,7‐Di­methyl­octa‐2,6‐dienyl­oxy)‐1,8‐di­hydroxy‐6‐methyl‐9,10‐anthra­quinone

The 9,10-anthra­quinone ring system of the title compound, C25H26O5, is essentially planar. The O-geranyl substituent is at the meta position with respect to the hydroxyl group. O—H⋯O intramolecular hydrogen bonds are observed in the molecular structure. The molecules form centrosymmetric hydrogen-bonded dimers via intermolecular C—H⋯O hydrogen bonds which generate rings of motif R22(10). The crystal structure is further stabilized by weak π–π interactions.
3-(3,4-Dimethoxyphenyl)-4-(2-methoxyanilino)furan-2(5H)-one

In the title compound, C19H19NO5, the furanone unit makes a dihedral angle of 30.93 (6)° with the benzene ring and a dihedral angle of 9.51 (6)° with the aniline ring. In the crystal, intermolecular C—H⋯O hydrogen bonds and C—H⋯π contacts link the molecules into sheets. A weak intramolecular hydrogen bond is also observed.
(1-Adamantyl)diphenylmethanol

In the title compound, C23H26O, the adamantane cage consists of three fused cyclohexane rings in classical chair conformations with absolute values of the C—C—C angles in the range 106.57 (11)–111.56 (12)°. The dihedral angle between the two phenyl rings is 81.38 (4)°. Although a hydroxy group is present as a conceivable donor, no hydrogen bonds are observed in the crystal structure.
PATTERNS OF PRESCRIPTION & EFFICACY EVALUATION OF ANTIDEPRESSANTS IN A TERTIARY CARE TEACHING HOSPITAL IN EASTERN INDIA

Aim: Patterns of Prescription & efficacy evaluation of Antidepressants in a tertiary care teaching hospital of Eastern India. Objective: Depression is associated with marked personal, social and economic morbidity affecting 9.5% of population worldwide. Prompt diagnosis and treatment can alleviate symptoms in over 80% of the cases. Present study investigates the prescribing patterns of different antidepressants & correlates the use of different antidepressant groups with their efficacy by using standardized tools for evaluation of efficacy. Subjects & Methods: A prospective, observational and cross sectional study was conducted in the out-patient department of Psychiatry in I.M. S & SUM Hospital in collaboration with S.C. B. Medical College & Hospital. A total of 160 cases were enrolled for the present study to investigate the prescribing pattern of antidepressants using a predesigned format. Statistical Analysis : Statistical analysis for both pattern of use & efficacy were done using chi square test & Wilcoxson’s signed rank test respectively. Results: Females suffered from depression more than their male counterparts. Unmarried people suffered more from depression and most of them had background stressors in life. Monotherapy was practiced more frequently than polytherapy with 2or more drugs. Selective Serotonin Reuptake Inhibitors (SSRI) like Escitalopram was found out to be the most preferred antidepressant among the psychiatrists of this hospital. Conclusion: Thus, out of three major antidepressant groups of drugs being prescribed for the treatment of depression, selective serotonin reuptake inhibitors are preferred over others because of their better side effect profile.
A comparison of liquid and solid culture media with radiometric system for detection of mycobacteria in clinical specimens

The present study was done on 100 consecutive specimens, received in the tuberculosis laboratory for culture of mycobacteria to determine the sensitivity of and time taken by Lowenstcin Jensen (IJ) medium, Middlcbrook 7H9(MB7H9) broth and BACTEC 460 TB radiometric system. Out of 100, a total of 59 specimens tested positive for acid fast bacilli (AFB) by microscopy and 65 were culture positive by one or another culture technique. In all, 59 were positive on LJ medium with sensitivity of 90.8% and average detection time of five weeks, 60 were positive by BACTHC radiomctric system with sensitivity of 92.3% and average detection time of three weeks and MB7H9 broth showed positive growth in 45 specimens with average detection time of six weeks and sensitivity of 62.9%. Two cases were detected by LJ medium. 3 by BACTHC and one by MB7F19 broth exclusively. ‘I he results suggest that although LJ and BACTEC arc more sensitive culture methods than MB7H9 broth and BACTEC is more rapid and sensitive than the other two, yet none are 100% sensitive. Simultaneous use of all the three is suggested for more efficient isolation of mycobacterium species
Strategies to prevent potentially inappropriate prescribing and adverse drug reactions in older patients

Title Strategies to prevent potentially inappropriate prescribing and adverse drug reactions in older patients Author(s) Cullinan, Shane Publication date 2015 Original citation Cullinan, S.P. 2015. Strategies to prevent potentially inappropriate prescribing and adverse drug reactions in older patients. PhD Thesis, University College Cork. Type of publication Doctoral thesis Rights © 2015, Shane P. Cullinan. http://creativecommons.org/licenses/by-nc-nd/3.0/
Study of childhood hansens disease at a tertiary care centre

Leprosy is an infectious disease caused by Mycobacterium leprae. Significant numbers of children are seen to be affected in high endemic regions. The number of childhood leprosy cases is important to de termine the level of disease transmission and can be considered as an index of prevalence of disease in the population. The percentage of childhood leprosy in the state of Maharashtra was 12.70 during the year 2012-2013 with a prevalence of leprosy 0.92. During the year 2011-2012, the percentage of child leprosy was 13.04 with prevalence of 1.07.
Discrimination against older people

The increasing number of old people is becoming a growing policy concern. Negative attitudes towards old people raise questions about the extent to which discrimination against old people exists and elder abuse occurs. This paper describes the occurrence of discrimination against old people and elder abuse, as well as the factors related to it, based on a review of (scientific) literature, official documents and the actions of legal bodies. Frequent or regular age discrimination, as experienced by old people themselves, is reported by a quarter of European citizens. Data on elder abuse vary and are often not representative; the same goes for data on inequality. Nevertheless, the analysis shows that discrimination against old age and elder abuse occurs regularly in the ‘western world’. Vulnerable old people are especially at risk. National and regional, multi-component action plans are recommended to combat discrimination against old people.