Miracle-dz/UniFAR-FTUs huggingface dataset:
Crosstalk between the Producers and Immune Targets of IL-9

IL-9 has been reported to play dual roles in the pathogenesis of autoimmune disorders and cancers. The collaboration of IL-9 with microenvironmental factors including the broader cytokine milieu and other cellular components may provide important keys to explain its conflicting effects in chronic conditions. In this review, we summarize recent findings on the cellular sources of, and immunological responders to IL-9, in order to interpret the role of IL-9 in the regulation of immune responses. This knowledge will provide new perspectives to improve clinical benefits and limit adverse effects of IL-9 when treating pathologic conditions.
The Influence of Employee Competency and Career Management on Career Commitment: Regional Government in Indonesia

This study aims to test the influence of employee competency and career management on career commitment in Indonesia. The study uses the cross-sectional data of regional government employees collected from February to April 2020. Regression and structural equation modeling are employed. The results base on the effect of employee competency and career management on career commitment in Indonesia are in line with the existing theory (i.e., Bandura’s Career Theory). Employee competency has a significant positive influence on career management and career commitment, which shows that regional government employees with high competency generate effective career management, and in turn career commitment increased. Regional governments with their career management program should formulate human resources management practice policy (e.g., career support, training, career development program, and orientation programs) in order to increase their competency. The positive effect of employee competency on career management is because of the effective training and career development program. The positive influence of career management on career commitment is due to the regional government providing an attractive career program, thus, employees’ career commitment improved. The positive influence of employee competency on career commitment via career management is implemented by regional government support to improve the career management program.
Testicular Biometry for Breeding Soundness Evaluation of Sahiwal Males Reared under Tropical Conditions

Background: The testicular biometry such as scrotal circumference (SC) and scrotal volume, affect semen quality hence bull fertility and thus testicular biometry can be used for breeding soundness of bulls. Methods: The present study was carried out to study the testicular parameters of 77 Sahiwal males of different ages and to establish its importance for selection of breeding bulls during 2015-2016 at ICAR-NDRI, Karnal. The testicular biometry of each male was done at monthly intervals using Vernier calliper, cloth tap and ultrasonography. Result: The semen quality parameters were significantly (P less than 0.05) more in the group having higher scrotal circumference. The scrotal circumference follows the curvilinear manner of growth from 12 months to greater than 72 months (correlation value of 0.92 and R2 0.84). The paired testicular volume (PTV) differed significantly (P less than 0.05) between different age group males. Scrotal circumference and paired testicular volume are directly related to semen quality hence bull fertility. Thus, testicular biometry is an important criterion for breeding soundness for selecting Sahiwal males.
Calculation of the frequencies and intensities in the infrared spectrum of the ethyl radical

The infrared spectra of matrix isolated ethyl radicals have been simulated by a normal coordinate calculation, fitting the vibrational frequencies of all, partially and fully deuterated species CH3CH2⋅, CH3CD2⋅, CD3CH2⋅, and CD3CD2⋅, together with the calculation of the IR intensities by modified CNDO and INDO open shell procedures. A good reproduction of the observed spectra is in agreement with the theoretical molecular geometry and the special structural features shown by deviations of the force constants for the ethyl radical compared to that of related saturated and unsaturated hydrocarbons.
The Effect of Lactation Number on Physico-Chemical and Microbiological Parameters of Milk from Small and Medium Bovine Farms located in Transilvania Region

Milk is a biological fluid where fats are distributed in microglobules (2-10 million/cm3), in an aqueous solution of proteins, carbohydrates and other substances. The main physico-chemical properties of milk are: density, viscosity, specific heat, boiling point, freezing point, pH and total acidity. Microbiological quality is represented by the presence or absence of pathogens or alterations, which can contaminate milk as a raw material. The comparative nutritional and microbiological quality of milk from three counties, from Transilvania Region, were fat percentage, total protein, casein content, lactose, pH, urea, total germ count (TGC) and somatic cell count (SCC). The best percentages of fat were obtained in Bihor County, with mean values of all lactations of 4.00%. This was followed by Hunedoara County with 3.97% and Alba County with 3.95%. The highest protein percentages were obtained in samples collected in Bihor County, with mean values of 3.57%, followed by Hunedoara County with 3.52% and Alba County with 3.51%. Most physicochemical indices fall within the normal limits, unanimously accepted by existing standards, but microbiological indices in some cases do not meet the requirements for the admission of raw milk.
Dissecting the Roles of Cuticular Wax in Plant Resistance to Shoot Dehydration and Low-Temperature Stress in Arabidopsis

Cuticular waxes are a mixture of hydrophobic very-long-chain fatty acids and their derivatives accumulated in the plant cuticle. Most studies define the role of cuticular wax largely based on reducing nonstomatal water loss. The present study investigated the role of cuticular wax in reducing both low-temperature and dehydration stress in plants using Arabidopsis thaliana mutants and transgenic genotypes altered in the formation of cuticular wax. cer3-6, a known Arabidopsis wax-deficient mutant (with distinct reduction in aldehydes, n-alkanes, secondary n-alcohols, and ketones compared to wild type (WT)), was most sensitive to water loss, while dewax, a known wax overproducer (greater alkanes and ketones compared to WT), was more resistant to dehydration compared to WT. Furthermore, cold-acclimated cer3-6 froze at warmer temperatures, while cold-acclimated dewax displayed freezing exotherms at colder temperatures compared to WT. Gas Chromatography-Mass Spectroscopy (GC-MS) analysis identified a characteristic decrease in the accumulation of certain waxes (e.g., alkanes, alcohols) in Arabidopsis cuticles under cold acclimation, which was additionally reduced in cer3-6. Conversely, the dewax mutant showed a greater ability to accumulate waxes under cold acclimation. Fourier Transform Infrared Spectroscopy (FTIR) also supported observations in cuticular wax deposition under cold acclimation. Our data indicate cuticular alkane waxes along with alcohols and fatty acids can facilitate avoidance of both ice formation and leaf water loss under dehydration stress and are promising genetic targets of interest.
Important Indicators in Increasing Nurse Loyalty in The Covid-19 Pandemic Time

Hospital is a means of health efforts that carry out health service activities and is a service provider institution. Health services in a hospital have an important role in achieving success in hospital services. This study aims to determine the effect of intrinsic motivation, leadership, supervision, intrinsic motivation on the satisfaction and loyalty of nurses in Ganesha General Hospital. The number of samples involved was 84 people using random sampling. Data collection was carried out using a questionnaire. Data analysis techniques using smartPLS. The results showed that intrinsic motivation has a positive effect on job satisfaction. Leadership has a positive effect on job satisfaction. Supervision has a positive effect on job satisfaction in nurses. Intrinsic motivation has a positive effect on job loyalty. Supervision has a positive effect on job loyalty. Job satisfaction has a positive effect on job loyalty to nurses at Ganesha General Hospital.
Narrative Engagement and Interpersonal Communication about Substance Use on Adolescent Substance Use Behaviors: A Case Study of Keepin’ it REAL

The present study examined direct and indirect effects of adolescent narrative engagement on substance use behaviors via refusal self-efficacy. This study also tested moderation effects of communication about substance use with parents, siblings, and friends on substance use behaviors. Students in 8th grade (N = 225) participated in surveys at two different time points. Path analyses revealed a positive association between identification with main characters and refusal self-efficacy as well as negative associations between refusal self-efficacy and the past 30-days substance use. Communication with parents and friends significantly moderated the relationship between refusal self-efficacy and the past 30-days substance use.
Simvastatin-Loaded Nanomicelles Enhance the Osteogenic Effect of Simvastatin

Objectives. The present study intended to further verify that simvastatin-loaded nanomicelles (SVNs) enhanced the role of simvastatin (SV) in promoting osteoblast differentiation in vitro and to evaluate the effect of SVNs on bone defect repair in vivo. Methods. SVNs were synthesized by dialysis. MG63 cells were subjected to intervention with 0.25 μmol/l of SVNs and SV. A 3-(4,5-dimethylthiazol-2-yl)-5-(3-carboxymethoxyphenyl)-2-(4-sulfophenyl)-2H-tetrazolium (MTS) assay kit and flow cytometry were used to determine cell proliferation activity, cell cycle distribution, and apoptosis. The osteoblastic differentiation of MG 63 cells was evaluated by measuring alkaline phosphatase (ALP) activity, ALP staining, and the expression levels of the osterix (Osx) and osteocalcin (OC) proteins. In addition, 0.5 mg of SVNs or SV was applied to the skull defect area of rabbits. Micro-CT, hematoxylin and eosin (HE) staining, and Masson’s trichrome staining were used for qualitative and quantitative evaluation of new bone in three dimensions and two dimensions. Results. The SVNs had a mean diameter of 38.97 nm. The encapsulation and drug-loading efficiencies were 54.57 ± 3.15 % and 10.91 ± 0.63 % , respectively. In vitro, SVNs and SV can inhibit the proliferation activity and promote osteogenic differentiation of MG63 cells by arresting MG63 cells at the G0/G1 phase without increasing the apoptosis rate. In vivo quantitative results showed that the bone mineral density (BMD), bone volume (BV)/total volume (TV) ratio, and trabecular number (Tb.N) in the gelatin sponge with SVNs (SVNs-GS) group and gelatin sponge with SV (SV-GS) group were 362.1%, 292.0%; 181.3%, 158.0%; and 215.2%, 181.8% of those in the blank control (BC) group, respectively. Histological results identified the new bone tissue in each group as irregular fibrous bone, and the arrangement of trabecular bone was disordered. There were significantly more osteoblasts and new capillaries around the trabecular bone in the SVNs-GS group and SV-GS group than in both the BC and drug-free nanomicelle (DFNs) groups. Both in vitro and in vivo, SVNs exhibited greater osteogenic efficacy than SV. Conclusion. SVNs significantly improved the osteogenic efficacy of SV.
Experimental investigation and comparison of subcooled flow boiling of TiO2 nanofluid in a vertical and horizontal tube

In this study, variations of local heat transfer coefficient are obtained in subcooled flow boiling conditions for water/TiO2 nanofluid in a vertical and horizontal tube. The results for the base fluid are compared with the predictions of the well known Shah correlation and Gnielinski formula for laminar and turbulent flows for single-phase forced convection and also with Chen correlation for subcooled flow boiling. A good agreement between the results is realized. At the subcooled regime, heat transfer coefficient of nanofluid is less than that of the base fluid and it decreases by increasing nanoparticle concentration for both of the channels; however, addition of the nanopraticles into the fluid causes that the vapor volume fraction increases.
Knowledge, attitude and motivation toward stem cell transplantation and donation among Saudi population in Riyadh: Are Saudi people aware enough about the importance of stem cell transplantation and donation?

Stem cell transplantation is considered nowadays an important lifesaving therapy for various fatal blood diseases including cancers, certain inherited blood diseases, and some diseases of the immune system (NHS). This type of cells differ from other cells in the body by having the ability to divide and renew themselves for long period as well as the ability to differentiate into all cells of the body (knowledge and perception). Working as a repair system within various types Abstract
In the Money: Gender and Jockey Success on the Thoroughbred Racetrack

This paper examines the relative performance and access to mounts of female jockeys in American horseracing, the only major professional sport where female and male athletes directly compete on a regular basis. We modeled the determinants of the probability for a jockey finishing a race “in-the-money”—placing first, second, or third, and the determinants for receiving mounts. Among other findings, the results indicated that the probability for female jockeys finishing a race in the money was not significantly different from male jockeys, ceteris paribus, yet female jockeys continue to receive fewer mounts after controlling for other relevant, observable factors.
Solving Steiner trees: Recent advances, challenges, and perspectives

The Steiner tree problem (STP) in graphs is one of the most studied problems in combinatorial optimization. Since its inception in 1970, numerous articles published in the journal Networks have stimulated new theoretical and computational studies on Steiner trees: from approximation algorithms, heuristics, metaheuristics, all the way to exact algorithms based on (mixed) integer linear programming, fixed parameter tractability, or combinatorial branch‐and‐bounds. The pervasive applicability and relevance of Steiner trees have been reinforced by the recent 11th DIMACS Implementation Challenge in 2014 and the PACE 2018 Challenge. This article provides an overview of the rich developments from the last three decades for the STP in graphs and highlights the most recent computational studies for some of its closely related variants.
Affecting Factors Teacher Work Satisfaction

Abstract. This study aims to determine the factors that effect teacher job satisfaction. In obtaining the data, a quantitsative approach is used with an explanatory coreeelational design because it aims to describe and measure the degree of relationship between variables in causal modeling using part analysis. The results showed that:First, leadership has a direct effect on teacher job satisfaction with a path coefficient of 0.173. Second, self esteem has a direct effect on teacher job satisfaction with a path coefficient of 0.173.
Distribution and frequency of mating types of Rhynchosporium commune in central Alberta

Abstract Rhynchosporium commune, the cause of barley scald, is an important disease of barley in Canada. Multiple studies have indicated that cryptic sexual reproduction may occur between opposite mating types (MAT1-1 and MAT1-2). The occurrence of R. commune mating types in Canada has not been determined previously. Infected leaves from barley cultivars in seven commercial fields and three breeding nurseries in central Alberta were collected and subjected to multiplex PCR to assess the presence of scald mating types within the lesions. Mating types were determined in 410 scald lesions from 288 leaves. Over 10% of lesions contained both mating types, and 44% of leaves with more than one lesion analyzed were colonized by both mating types. The mating types significantly deviated from the 1:1 ratio that would have been expected with frequent sexual reproduction. MAT1-2 was more common in six of the ten locations and for the region as a whole. The presence of both mating types, often in close proximity to each other, suggests that the cryptic sexual stage could be present in Alberta if it does occur. The skewed mating type ratio does suggest, however, that asexual reproduction is predominant within the pathogen population.
Managing brands in tough times: A review of literature for future marketing

Branding is absolutely critical to a business because of the overall impact it makes on your company. Branding can change how people perceive your brand, it can drive new business and increase brand awareness. Branding is important because not only is it what makes a memorable impression on consumers but it allows your customers and clients to know what to expect from your company. It is a way of distinguishing yourself from the competitors and clarifying what it is you offer that makes you the better choice. Your brand is built to be a true representation of who you are as a business, and how you wish to be perceived. A quick look at recent history shows economic recessions are fairly regular occurrences. Uncomfortable readjustments for us wayward, over-borrowing, rather greedy inhabitants of the developed world. Maybe not all of us, but enough to set the relentless ripple effect in motion. Whether this current event turns into its bigger brother, a full-blown depression remains to be seen. But what is certain is that businesses who use these tough times wisely, as opposed to adopting a siege mentality, will come out the other end in a much better position. The paper highlights the brand management tactics in tough times with the review of research.
Study framing influences crowdsourced rates of problem gambling and alcohol use disorder.

OBJECTIVE Crowdsourcing is an increasingly popular source of participants in studies of problem gambling. Studies with crowdsourced samples have reported prevalence rates of problem gambling between 10 and 50 times higher than traditional sources of estimates. These elevated rates may be due to study framing motivating self-selection. In this preregistered study, we examined whether study framing influences self-reported problem gambling severity and harmful alcohol use in a sample of participants recruited from a popular crowdsourcing website. METHOD Two recruitment notices for an online questionnaire were placed on Amazon Mechanical Turk (MTurk). Notices were framed as "Gambling and Health" or "Alcohol and Health. " Only participants who passed data checks were retained for confirmatory analyses (N = 564; 44% of recruited participants). Participants in the gambling framing (N = 261) and in the alcohol framing (N = 303) were compared on the Problem Gambling Severity Index (PGSI) and Alcohol Use Disorders Identification Test (AUDIT). RESULTS Problem gambling rates and severity scores were significantly greater for participants in the gambling framing compared to those in the alcohol framing. Self-reported scores of harmful alcohol use were significantly greater for participants in the alcohol framing compared to those in the gambling framing, but there was no significant difference in prevalence rates for harmful alcohol use. CONCLUSIONS Study framing is an important consideration for gambling and alcohol research. We found that study framing may substantially increase the observed rates of problem gambling severity in crowdsourced samples, potentially via encouragement of self-selection. (PsycInfo Database Record (c) 2021 APA, all rights reserved).
The Use of Blended Learning in EFL (Writing Skills): A Case for Rosetta Stone Software

The purpose of education at Moscow Aviation Institute (MAI) is to qualify highly trained professionals who are ready to communicate and also take part in scientific sphere. We have created an English language course that blends in person instruction enhanced with wiki interactive tools. This study tests Rosetta stone software on MAI students’ writing skills. We decided to find the difference between the results of blended learning approach as alternative to traditional course of EFL, especially we were focused on the progress in writing skills. We decided to start this hybrid course for some reasons: to encourage the students of MAI to read, speak and especially write properly; to find new ways of interaction between the professors and the students. Rosetta stone blended course is one of the key online language learning programs of educational success nowadays. Hence, we designed a treatment using Rosetta Stone software to examine its effect on EFL students’ writing skills at MAI. Our department of linguistics and translation is well-equipped with modern personal computers, web cameras etc. A sample of 48 technical first-year students started a language course at MAI. 24 students represented the control group, and 24 students represented the experimental group. The control and experimental groups were taught by the same program. Throughout the course, the learners working within the framework of traditional paradigm followed the typical communicative approach routine. The participants of the experimental group were instructed to view the material posted on Rosetta Stone platform and to do extra homework several times a week. Among the benefits of course we can name: accessibility of materials, students’ desire to study and to test something new, an opportunity to study whenever and wherever they want, ability to concentrate indoors home, progress in writing and other skills. The analysis revealed that the experimental group outstriped the control group with traditional way of education. In conclusion, we can say, that blended learning can successfully improve the progress in writing skills of EFL studies at MAI.
Magnesium and zinc complexes of a potentially tridentate β-diketiminate ligand

The synthesis of the unsymmetrically substituted β-diketimine, 2-(2-methoxyphenylimino)-4-(2,6-diisopropylphenylamido)pent-2-ene, (BDI-2)H, is described and its complexation chemistry with magnesium and zinc is explored. Emphasis is placed on the preparation of alkoxide and amide derivatives for the ring-opening polymerisation of lactide; their behaviour as polymerisation initiators is compared to analogous compounds supported by the N,N′-bis(2,6-diisopropylphenyl) β-diketiminate ligand, BDI-1. (BDI-2)H reacts with Me2Mg to give the bis(chelate) complex, (BDI-2)2Mg, 3. Magnesium alkyls supported by BDI-2 may be prepared by increasing the size of the alkyl group. Hence, lithiation of (BDI-2)H affords [(BDI-2)Li]2, 4; its subsequent treatment with iPrMgCl produces (BDI-2)MgiPr, 5. Aminolysis of complex 5 using iPr2NH yields the amide complex, (BDI-2)MgNiPr2, 6. Zn(NTMS2)2 and ZnEt2 react with (BDI-2)H to give (BDI-2)Zn(NTMS2), 7, and (BDI-2)ZnEt, 8, respectively. The former is converted into the siloxide complex,(BDI-2)Zn(OSiPh3), 9, upon reaction with Ph3SiOH. The chloride derivative, (BDI-2)ZnCl, 10, has also been prepared via the reaction of ZnCl2 with 4. Crystallographic analysis of compounds 3, 4, 7 and 8 reveals that the potential for (BDI-2) to bind in a tridentate manner is only realised with the more electrophilic metals Li and Mg. Compared to their (BDI-1) counterparts, complexes 6, 7 and 9 are more active, but less well-controlled, initiators for the ring-opening polymerisation of rac-lactide, a consequence of the diminished steric protection afforded by (BDI-2) relative to (BDI-1).