Miracle-dz/UniFAR-FTUs huggingface dataset:
Impact of diabetes on prognosis of gastric cancer patients performed with gastrectomy

Objective This study aimed to determine the impact of type 2 diabetes mellitus (T2DM) on clinical outcomes of gastric cancer (GC) patients and explore whether metformin use and good glycemic control could reverse it. Methods Clinicopathologic data of consecutive GC patients who underwent gastrectomy at Nanfang Hospital between October 2004 and December 2015 were included. Propensity score matching (PSM) was performed to balance the important factors of the disease status between non-T2DM and T2DM group. The last follow-up time was January 2019. Results A total of 1,692 eligible patients (1,621 non-T2DM vs. 71 T2DM) were included. After PSM, non-T2DM group (n=139) and T2DM group (n=71) were more balanced in baseline variables. The 5-year cancer-specific survival (CSS) rate in T2DM group (47.0%) was inferior to that in non-T2DM group (58.0%), but did not reach statistical significance [hazard ratio (HR)=1.319, 95% confidence interval (95% CI): 0.868−2.005, P=0.192]. While the 5-year progress-free survival (PFS) rate of T2DM group (40.6%) is significantly worse than that in non-T2DM group (56.3%) (HR=1.516, 95% CI: 1.004−2.290, P=0.045). Univariate and multivariate analyses showed that T2DM was an independent risk factor for PFS but not for CSS. In T2DM group, metformin use subgroup was associated with superior 5-year CSS and PFS in compared with non-metformin use subgroup, although the difference was not statistically significant (5-year CSS: 48.0%vs. 45.4%, HR=0.680, 95% CI: 0.352−1.313, P=0.246; 5-year PFS: 43.5%vs. 35.7%, HR=0.763, 95% CI: 0.400−1.454, P=0.406). The 5-year CSS rate was 47.5% in good glycemic control subgroup and 44.1% in poor glycemic control subgroup (HR=0.826, 95% CI: 0.398−1.713, P=0.605). And both two subgroups yielded a similar 5-year PFS rate (42.2%vs. 36.3%, HR=0.908, 95% CI: 0.441−1.871, P=0.792). Conclusions DM promoted disease progress of GC after gastrectomy but had not yet led to the significant discrepancy of CSS. For GC patients with T2DM, metformin use was associated with superior survival but without statistical significance, while better glycemic control could not improve the prognosis.
Beta-casein A1/A2, kappa-casein and beta-lactoglobulin polymorphisms in Turkish cattle breeds

Abstract. In this study, the genetic diversity of three milk protein genes namely beta-casein, kappacasein and beta-lactoglobulin was estimated in Turkish cattle breeds. Based on these genes, breeds in Turkey have been grouped as: 1) Eastern Anatolian Red, Anatolian Black and Southern Anatolian Red and 2) Turkish Grey, Turkish Holstein and Holstein Candidate Bulls. B alleles of the three studied genes, which were reported to be positively related with cheese yield and quality, seemed to be low-intermediate for beta-casein and kappa-casein but relatively high for beta-lactoglobulin in the first group of Turkish breeds compared to other breeds of the world. The kappa-casein E allele, which has a negative effect on cheese quality, is absent in Turkish cattle breeds, except in Holstein Candidate Bulls. Therefore, the results suggest that milk of Turkish native breeds is suitable for cheese making. Based on observations of the Turkish breeds, some suggestions were made regarding breeding practices in Turkey.
Population-based Large-scale longitudinal analysis of relationship between asthma and neoplasia

Background A relationship between asthma and the development of cancer has been reported, but remains controversial because of contradictory results from population studies. Methods Two large-scale observational, all payers claim datasets from the US-based Healthcare Cost and Utilization Project (HCUP) were used for discovery and validation. Associations between asthma and neoplasms were discovered using Causal Inference Using Composition of Transitions (CICT) in data from the State of Florida. Validation was completed in eight case-control cohorts for patients exposed to subtypes of asthma and COPD using data from the State of California. Control groups were matched on gender, age, race and history of tobacco abuse. Odds ratio analysis with Bonferroni-Holm correction measured the association of asthma and COPD with 26 different neoplasms. ICD9CM codes were used to identify exposures and outcomes. Findings CICT identified 17 association between asthma and neoplasms in the discovery datasets. In the validation dataset, 208 case-control, analyses were conducted between subtypes of Asthma (N= 999,370, male= 33%, age= 50) and COPD (N=715,971, male = 50%, age=69) with the corresponding matched control groups (N=8,400,004, male= 42%, age= 47). Allergic asthma was associated with benign neoplasms of the meninges, salivary, pituitary, parathyroid, and thyroid glands (OR:1.52 to 2.52), and primary malignant neoplasms of breast, hematopoietic, and lymphatic system (OR: 1.45 to 2.05). COPD was associated with neoplasms in the lung, bladder and hematopoietic system. Interpretation The combination of machine learning for the discovery of associations with epidemiological methods for validation shows that allergic asthma is associated with neoplastic transformation of common structures of secretory organs. Funding None.
Foreign-body Ingestions in Children During COVID-19 Pandemic in a Pediatric Referral Center

In February 2020, the COVID-19 pandemic overwhelmed Italy. We retrospectively reviewed all attendances and emergency (A&E) admissions due to foreign-body ingestions (FBIs) to an Italian pediatric referral hospital, from February 24 to April 24, 2020, COVID-19 lockdown and compared them with the same period in the previous 4 years. A total of 101 cases were recorded. Mean age of admission was 4.6 years. Groups did not differ for gender (P = 0.4) or age (P = 0.3). Among FBIs ingestions, 24.0% occurred in children with <2 years of age and 47.5% in children from 2 to 6 years of age. In the 2020 study period, 9 patients were seen for batteries ingestion compared with a median value of one among compared periods. The rates of batteries ingestions increased significantly over the observational period (P < 0.001). We report a dramatic increase in batteries ingestions in children, a potentially fatal event, during the COVID-19 pandemic lockdown.
Modeling the Electro-chemical Properties of Microbial Opsin ChrimsonR for Application to Optogenetics-based Vision Restoration

Optogenetic activation of neurons [1] have greatly contributed to our understanding of how neural circuits operate, and holds huge promise in the field of neural prosthetics, particularly in sensory restoration. The discovery of new channelrhodopsins, Chrimson — which is 45 nm more red-shifted than any previously discovered or engineered channelrhodopsin — and its mutant ChrimsonR with faster kinetics [2] made this technology available for medical applications. However, a detailed model that would be able to accurately reproduce the membrane potential dynamics in cells transfected with ChrimsonR under light stimulation is missing. We address this issue by developing the first model for the electrochemical behavior of ChrimsonR that predicts its conductance in response to arbitrary light stimulation. Our model captures ON and OFF dynamics of the protein for stimuli with frequencies up to 100 Hz and their relationship with the brightness, as well as its activation curve, the steady-state amplitude of the response as a function of light intensity. Additionally, we capture a slow adaptation mechanism at a timescale at the order of minutes. Our model holds for light intensities covering the whole dynamic range of the channel (from response onset to saturation) and for timescales in the order of up to several minutes. This model is a new step towards modeling the spiking activity of ChrimsonR-expressing neurons, required for the precise control of information transmission in optogenetics-based Brain-Computer Interfaces, and will inform future applications of ChrimsonR based optogenetics.
KEANEKARAGAMAN JAMUR ARBUSKULA DI PULAU ENGGANO [Diversity of Arbuscular Fungi in Enggano Island]

A study on diversity of arbuscular fungi (AF) in forest area and small plantation in eastern part of Enggano island was done. Twelve species of AF were identified from this island. Eleven species had been reported from Java and associated with different kinds of plant, but three species i.e. Gigaspora gigantea, Glomus multicaule and Scutellospora heterogama were not common, while Sclerocystis taiwanensis is a new record for Indonesia. All species of AF recorded from this island were described by their morphological characters and their distribution in Enggano island were presented.
Evaluation of Antidepressant Activity of Hydroalcoholic Extract of Commiphora Mukul (Engl.), Burseraceae in Mice.

Commiphora mukul (CM) is reported for several neurological disorders, but it is not been reported for its antidepressant activity. The aim of the present work was to evaluate the antidepressant activity of a hydroalcoholic extract of Commiphora Mukul (HECM) and its chloroform and ethyl acetate fractions using acute depression models in mice. The effects of acute oral pretreatment of HECM (50, 100, or 200 mg/kg p.o.), chloroform soluble fraction and ethyl acetate soluble fraction of HECM (20mg/kg p.o. and 40 mg/kg p.o.) and fluoxetine (10 mg/kg p.o.) were evaluated using force swim test (FST) and tail suspension test (TST) in mice. Immobility duration in FST and TST was measured one hour after of all the treatments. At the end of TST plasma corticosterone was measured. Both HECM and both the fractions showed dose dependent normalization of immobility duration in both the parameters along with the normalization of plasma corticosterone levels. HECM exerts antidepressant effect in acute models of depression in mice.
Effects of Replaced Plant Oils on the Quality Properties in Low-Fat Hamburger Patties

Effects of substituting olive, corn, soybean, and sunflower oils (each at 50% substitution) on chemical composition and sensory quality of beef hamburger patties were determined. Although beef patties added with plant oils were not different in chemical composition to control (added beef fat 10%), they had 2.0-3.8% lower caloric contents, 3.7-5.9% lower cooking loss, and less diameter and thickness changes after cooking. Beef patties with olive oil had lowest before and after cooking. In textural properties, control had higher hardness, cohesiveness, and gumminess than patties with plant oils, whereas no differences in springiness were observed between control nod all plant oil-treated patties. Beef patties containing olive oil had higher scores for overall acceptability than other patties.
Annual cycle of White-winged Scoters (Melanitta fusca) in eastern North America: migratory phenology, population delineation, and connectivity

Understanding full annual cycle movements of long-distance migrants is essential for delineating populations, assessing connectivity, evaluating crossover effects between life stages, and informing management strategies for vulnerable or declining species. We used implanted satellite transmitters to track up to 2 years of annual cycle movements of 52 adult female White-winged Scoters (Melanitta fusca (Linnaeus, 1758)) captured in the eastern United States and Canada. We used these data to document annual cycle phenology; delineate migration routes; identify primary areas used during winter, stopover, breeding, and molt; and assess the strength of migratory connectivity and spatial population structure. Most White-winged Scoters wintered along the Atlantic coast from Nova Scotia to southern New England, with some on Lake Ontario. White-winged Scoters followed four migration routes to breeding areas from Quebec to the Northwest Territories. Principal postbreeding molting areas were in James Bay and the St. Lawrence River estuary. Migration phenology was synchronous regardless of winter or breeding origin. Cluster analyses delineated two primary breeding areas: one molting area and one wintering area. White-winged Scoters demonstrated overall weak to moderate connectivity among life stages, with molting to wintering connectivity the strongest. Thus, White-winged Scoters that winter in eastern North America appear to constitute a single continuous population.
Response of Cowpea (Vigna Unguiculata L) Varieties to Defoliation

Loss of foliage in cowpea (Vigna unguiculata [L] Walp) as a result of field physiological disorders and/or diseases is detrimental to the growth and development of the crop in both tropical and sub-tropical areas. Field studies on effects of defoliation in cowpea were conducted at the University for Development Studies, Tamale in Northern Ghana during the 2015 and 2016 cropping seasons. Four cowpea varieties, namely Songotra, Padituya, Binaaba and Sanzi were subjected to the following five levels of defoliation: 0 %, 25 %, 50 %, 75 % and 100 %. The treatment combinations were replicated three times in randomised complete block design. Results indicated that the varieties differed from each other in terms of vegetative growth and yield responses to defoliation. The overall best grain yielder was Padituya whilst Binaaba was the poorest in terms of grain yield. Up to 50 % defoliation of any of the four varieties was not observed to be detrimental to growth and grain production. Keywords : Cowpea Varieties, Experimental Defoliation, Growth, Grain Yield
Mouthpart deformities in non-biting midge larvae from a cadmium contaminated stream in Northern Thailand.

Deformities in the mouthparts of non-biting midge larvae, particularly in the teeth of the mentum, were studied in cadmium polluted areas in Mae Tao Stream, Mae Sot District, Tak Province, Northern Thailand. Non-biting midge larvae were sampled together with water and sediment from 4 study sites: sites MT1 and MT2 were upstream to a zinc mine and unpolluted by cadmium; sites MT3 and MT4 were downstream and polluted with cadmium. From the water temperature, pH, electrical conductivity, total dissolved solids, dissolved oxygen, nitrate-nitrogen, ammonia-nitrogen, and orthophosphate, the stream water quality was classified as moderately clean. The cadmium concentrations MT3 and MT4 exceeded the European maximum permissible level of 3.0 mg/kg for agricultural soil. A total of 3067 larvae and 21 taxa representing 3 subfamilies (Chironominae, Orthocladiinae, and Tanypodinae) from the four sampling sites were screened for mentum deformities. The results indicated that the deformity incidence of larvae was 5% at MT3 and MT4 and 0.20% at MT1 and 0.75% at MT2. Hence the mouthpart deformities of non-biting midge larvae could be potentially used as a bio-indicator for cadmium pollution.
Genetic variability and character association studies for seed yield and component characters in soybean [Glycine max (L.) Merrill] under North-western Himalayas

The present investigation was undertaken to assess the genetic variability and character associations for seed yield and component characters in 307 soybean germplasm lines. The lines were raised in augmented block design in four blocks during kharif 2014. Out of these, twenty seven promising genotypes were selected and forwarded for evaluation along with four checks in randomized block design with three replications at CSKHPKV, Palampur (H.P) during kharif 2015. The analysis of variance revealed the presence of sufficient genetic variability in the breeding material. High PCV and moderate GCV were recorded for harvest index and biological yield/plant. High heritability coupled with high genetic advance were observed for harvest index followed by biological yield /plant, seed yield /plant, number of pods/plant and 100-seed weight indicating the predominance of additive gene action in controlling the trait. Number of branches /plant, number of seeds /pod, biological yield/plant and harvest index exhibited significantly positive correlation with seed yield /plant both at phenotypic and genotypic levels. Two traits viz., harvest index and biological yield /plant could be considered as direct selection indices for yield improvement in soybean.
Investigation of Fe2O3 with MgAl2O4 for chemical-looping combustion

Chemical-looping combustion (CLC) is a combustion technology with inherent separation of the greenhouse gas CO2. The technique involves the use of a metal oxide as an oxygen-carrier, which transfers oxygen from the combustion air to the fuel. The metal oxide Fe2O3 on MgAl2O4 support was examined, and particles of diameter 125−180 μm were prepared by freeze-granulation. The reactivity was evaluated in a fluidized-bed reactor, where the atmosphere was periodically changed. Reduction was performed in 50% CH4 and 50% H2O, while the oxidation was performed in 5% O2. The sintering temperature and the ratio of metal oxide/inert were varied in order to find the optimal particle properties. The particles were characterized with respect to crushing strength, surface structure, and chemical composition, and 60% Fe2O3 on 40% MgAl2O4 sintered at 1100 °C was found to be the most suitable oxygen carrier. The particle had a high reactivity and showed no tendency to agglomerate or break apart during the cyclic tests. The .
Predicting rapeseed oil content with near‑infrared spectroscopy

The objective of this work was to establish a calibration equation and to estimate the efficiency of near-infrared reflectance (NIR) spectroscopy for evaluating rapeseed oil content in Southern Brazil. Spectral data from 124 half-sib families were correlated with oil contents determined by the chemical method. The accuracy of the equation was verified by coefficient of determination (R2) of 0.92, error of calibration (SEC) of 0.78, and error of performance (SEP) of 1.22. The oil content of ten genotypes, which were not included in the calibration with NIR, was similar to the one obtained by the standard chemical method. NIR spectroscopy is adequate to differentiate oil content of rapeseed genotypes.
Disentangling Mandatory IFRS Reporting and Changes in Enforcement

We discuss “Mandatory IFRS Reporting and Changes in Enforcement” by Christensen, Hail, and Leuz (CHL, in this issue). We begin by discussing CHL in the context of prior literature, and subsequently discuss the research design, results, and inferences. CHL seeks to contribute to the literature by disentangling the liquidity benefits of changes in accounting standards from those of changes in enforcement. Taken at face value, we believe that the evidence in CHL suggests that both change in enforcement and adoption of International Financial Reporting Standards (IFRS) confer liquidity benefits. The largest benefits obtain when the change to IFRS reporting is combined with change in enforcement. This is not to say that enforcement conveys capital market benefits but IFRS reporting does not, or that IFRS reporting conveys capital market benefits but enforcement does not; both are necessary to confer capital market benefits.
PERCEPTIONS ON QUALITY OF LIFE IN MALAYSIA: THE URBAN-RURAL DIVIDE

Spatial strategy then known as regional planning, was conceptualized and formally institutionalized in the Second Malaysia Plan, to be among the major instruments of the New Economic Policy (NEP). Urbanization in this context was envisaged to help achieve the spatially balanced development target of the NEP, serving as a means to improve the socioeconomic status of the population in general, and increase the participation of Bumiputras in particular, in the modern urban sector (2nd Malaysia Plan, 1971). Conscious planning which characterizes the countryâ€™s development since independence has placed Malaysia currently to be among Asiaâ€™s best. The challenge of the concomitant rapid rate of urbanization however, continues to remain one of bridging the multidimensional urban-rural gaps. The National Urbanization Policy (NUP) and National Physical Plan (NPP) while fully cognizant of the potentially divisive globalization effect on national development, stress the enhancement of overall living qualities for sustainability. This paper seeks to explore the differences between the importance and satisfaction in living qualities between the urban and rural dwellers in 14 quality of life domains. These domains are Population and Family, Participation in Education, Human Resource, Health, Income, Expenditures and Savings, Housing, Environment, Transportation, Culture and Entertainment, National Unity, Communication and Technological Change, Social Participation, Public Safety and Social Security. Quality of Life Index in this study which is based on a questionnaire survey on 3,500respondents was derived using the Customer Satisfaction Index. It revealed a gap between the perceived importance and satisfaction rating for most of the quality of life domains studied. This gap prevailed for both rural and urban respondents.
Phenotypic Correlations in Broiler Breast Meat Quality and some Welfare Criteria: Implications of Photoperiod Length and Light Intensity

The goals of this research were to estimate the phenotypic correlations among various meat quality traits, carcass parts weight, some blood parameters, and eye dimensions from a male broiler line and to describe the relation among these variables. Two photoperiod length groups and two light intensity groups of commercial meat-type broilers were used as treatments. A total of 272 1 day-old male broiler chicks (Ross 308) were randomly assigned to four treatment groups based on the photoperiod length and light intensity, with four replicates. Eight broilers from each group were used for colour measurement (CIE L*a*b*), pH, cooking loss, and water holding capacity at the age of 42 days. The pH at 24 hours after postmortem (pHu) was capable of directly interfering with the attributes of the meat, since this trait was inversely related with a*, water holding capacity and pH 15 mins postmortem (pH15) in the dim, reducing (DRLI) group, indicating an effect of pHu decrease during 24h postmortem on protein denaturation. This study demonstrates that the variables of poultry meat quality are related and that there is a phenotypical association between a* value, water holding capacity (WHC) and the other attributes of the meat. The pHu, a* value and WHC could be efficient meat quality indicators in this broiler line. Corticosterone (CORT) level had a significant positive correlation (r=0.323, P<0.05) with glucose level in the bright light (BLI) group. Eye weight had a significant correlation with all eye dimensios in increasing photoperiod length group.
RESPONSE OF WHEAT (TRITICUM AESTIVUM L.) PLANTS TO FOLIAR SPRAYING OF SOME BIO-STIMULANTS (YEAST EXTRACT, ARGININE, B12 AND THEIR INTERACTIONS)

A field experiments were carried out in season of 2013/2014 at Botanical garden, Botany and Microbiology Dept., Fac. ofSci. , Al- Azhar Univ., Nasr City, Cairo, to study the effect of foliar applications of some bio-stimulants (dry yeast extracts, arginine,B12 and their interactions) on growth, total yield, quality and some chemical constituents of wheat plants. Results showedthat, foliar spraying of wheat plants with bio-stimulants especially yeast extract had a significant effect on vegetative growth,yield and quality. Shoot fresh weight of wheat plants were improved by yeast extract at all doses and B 12 foliar applicationduring the first stage. Results showed that addition of any of these treatments has been significantly increased the dry weight ofroots during two stages as compared to the control in almost cases. The contents of pigments of wheat plants showed, significantincreases in chlorophyll a, b, a+b and carotenoids content in response to various treatments. Results indicated that foliarapplication of all these treatments increased amylase activity compared to control during the second stage. Application of yeast(6 g l-1) + B12 or yeast (6 g l-1) + arginine showed the heaviest 100 seeds weight (4.16 and 4.11 g) respectively as a comparedwith untreated plant(2.9 g). Moreover it could be concluded that foliar spraying of yeast (4g/l) +Arg. led to obtain the highestvalues of yielded seeds protein, while the highest values of yielded carbohydrates at yeast (4g/l) +B12 of wheat plants.