Miracle-dz/UniFAR-FTUs huggingface dataset:
ANTIOXIDATIVE AND CARDIO-PROTECTIVE EFFECTS OF ETHANOLIC EXTRACT OF GINGER ON TRITON WR-1339 INDUCED HYPERLIPIDEMIA IN RATS

-The present study aimed to clarify the protective effect of ethanolic extract of ginger on Triton WR-1339 induced hyperlipidemia in rats. Forty male rats were randomly divided into four groups: control, Triton WR-1339 treated group received 250 mg/kg b.wt intraperitoneally (3 times per week), ginger treated group received ethanolic extract of ginger 400 mg/kg b.wt orally and ginger pretreated Triton WR-1339 group received Triton WR-1339 and ethanolic extract of ginger at the same doses for three weeks. Hyperlipidemic rats exhibited significant increase in serum total lipids, cholesterol, triacylglycerol, low density lipoprotein and very low density lipoprotein levels with reduction in serum high density lipoprotein level. Also, serum testosterone, progesterone, estradiol, triiodothyronine and thyroxine hormones, and aspartate trans-aminase, lactate dehydrogenase, creatine kinase and creatine kinase-MB isoenzyme activities, and Troponin I level were significantly increased. Cardiac malondialdehyde level was increased while glutathione-S-transferase, glutathione peroxidase, and glutathione reductase activities, and reduced glutathione level were significantly decreased. Treatment with ethanolic extract of ginger significantly reduced serum lipid levels and normalized serum biomarkers of cardiac functions, increased serum endocrine hormones and antioxidant enzymatic activities with subsequent decrease of malondialdehyde level. We concluded that ethanolic extract of ginger has a protective role against cardiac damaging effect of hyperlipidemia.
COMA CARE: Body Movement and Health Monitoring for COMA Patient using IoT

I oT is essential for keeping track of the wellbeing of coma patients. Through timely detection, constant ability observing can save up to 60% of human lives. The equipment is specifically made for real-time observing of coma patients' wellbeing meters. The usage of GSM and IoT has made it supplementary apt to identify the patient's situation or condition. For obtaining the patient's temperature, coronary temperament rate, eye crusade, and oxygen inundation probability. In this proposed technique includes a amount of smart instruments, including hotness, heartbeat, eye flicker, and SPO2 (bordering duct oxygen inundation) sensors. This system accelerometer sensor is being utilised to show the coma patients' movement. It has the capability to immediately inform a medical professional if several abrupt variations in the usual choice of body constraints occur, such by way of a drop or growth in physique heat or a surge in body fluid density that are not steady circumstances for improved fitness.
Becker Digital

Background: The character higher order scales (self-directedness, cooperativeness, and self-transcendence) in the temperament and character inventory are important general measures of health and well-being [Mens Sana Mono-graph 11:16–24 (2013)]. Recent research has found suggestive evidence of common environmental influence on the development of these character traits during adolescence. The present article expands earlier research by focusing on the internal consistency and the etiology of traits measured by the lower order sub-scales of the character traits in adolescence. Methods: The twin modeling analysis of 423 monozygotic pairs and 408 same sex dizygotic pairs estimated additive genetics (A), common environmental (C), and non-shared environmental (E) influences on twin resemblance. All twins were part of the on-going longitudinal Child and Adolescent Twin Study in Sweden (CATSS). Results: The twin modeling analysis suggested a common environmental contribution for two out of five self-directedness sub-scales (0.14 and 0.23), for three out of five cooperativeness sub-scales (0.07–0.17), and for all three self-transcendence sub-scales (0.10–0.12). Conclusion: The genetic structure at the level of the character lower order sub-scales in adolescents shows that the proportion of the shared environmental component varies in the trait of self-directedness and in the trait of coopera-tiveness, while it is relatively stable across the components of self-transcendence. The presence of this unique shared environmental effect in adolescence has implications for understanding the relative importance of interventions and treatment strategies aimed at promoting overall maturation of character, mental health, and well-being during this period of the life span
A New Approach to Juice Yield Loss in Oranges Following Freezing Weather

A new objective method of calculating yield loss in crops of oranges due to drying is presented. The method utilizes test house extraction data and historical nonfreeze year yield data for the crops. Yield loss calculations by the new method are compared to yield loss values de termined by USDA Federal Crop Insurance Crop adjusters using the dryness cut method. This study covers a total of 375,866 90 Ib (40.9 kg) boxes of early midseason and late varieties harvested and delivered to Florida processing plants after the January 1977 freeze. The new method may overcome 4 limitations of the dryness cut method. When variability of the dryness cut losses were compared to the variability of the calculated losses for iCooperative research of the Florida Department of Citrus and the University of Florida, IFAS, Agricultural Research and Education Center, Lake A\rred, Florida. 2The authors acknowledge the helpful review suggestions of Dr. B. A. Eagerman in simplification of the equation. Proc. Fla. State Hort. Soc. 90: 1977. the same crops, the dryness cut method showed significantly more variability at the 99.9% level. Citrus fruit left on the tree exhibit loss of juice by dry ing as a result of freezing weather. Consequently, freezing weather can result in serious economic losses to the grower. The equivalent of approx 1/3 of Florida's citrus crops were lost due to the 1977 freeze. The USDA administers the Federal Crop Insurance Corp. (FCIC) to alleviate these losses for participating growers. FCIG adjusters are re sponsible for evaluating crop losses due to freezing. Freeze damage and crop loss has long been estimated by the dry ness cut method (1) although its exact origin is unknown. Westbrook (6) lists an excellent bibliography of early work on frozen citrus fruit. The dryness cut method of evaluating frozen fruit is specified for use by USDA-FCIC adjusters (5) and also for use by Florida Department of Agriculture In spectors (3, 7) in determining U.S. grades of oranges (4) for shipment to the fresh fruit markets. The dryness cut method has the following serious limitations: 1. It is open to subjective errors such as: (a) visual esti mation of depth of cut, 1/4, 1/2, or 2/3 of the distance from the stem end to the blossom end or 1/4, 1/2, or 3/4 inch at the stem end, and (b) visual estimation of the extent of internal dryness at the cut surfaces (2, 4). 2. Required manual contact and visual appraisal of each fruit is time consuming and fatiguing. 3. Sampling is often done in the grove under widely varying conditions which precludes the more representative mechanically drawn sample associated with the test house analysis. 4. Training of new personnel and retraining old person nel at the occurrence of an infrequent freeze is a problem
Mechanisms Of Cannabinoid Cb 2 Receptor-Mediated Reduction Mechanisms Of Cannabinoid Cb 2 Receptor-Mediated Reduction Of Dopamine Neuronal Excitability In Mouse Ventral Tegmental Of Dopamine Neuronal Excitability In Mouse Ventral Tegmental Area Area

Background: We have recently reported that activation of cannabinoid type 2 receptors (CB 2 Rs) reduces dopamine (DA) neuron excitability in mouse ventral tegmental area (VTA). Here, we elucidate the underlying mechanisms. Methods: Patch-clamp recordings were performed in mouse VTA slices and dissociated single VTA DA neurons. Findings: Using cell-attached recording in VTA slices, bath-application of CB 2 R agonists (JWH133 or ﬁ ve other CB 2 R agonists) signi ﬁ cantly reduced VTA DA neuron action potential (AP) ﬁ ring rate. Under the patch-clamp whole-cellrecordingmodel,JWH133(10 μ M)mildlyreducedthefrequencyofminiatureexcitatorypostsynaptic currents (mEPSCs) but not miniature inhibitory postsynaptic currents (mIPSCs). JWH133 also did not alter evoked EPSCs or IPSCs. In freshly dissociated VTA DA neurons, JWH133 reduced AP ﬁ ring rate, delayed AP initiation and enhanced AP after-hyperpolarization. In voltage-clamp recordings, JWH133 (1 μ M) enhanced M-type K + currents and this effect was absent in CB 2 − / − mice and abolished by co-administration of a selective CB 2 R antagonist (10 μ M, AM630). CB 2 R-mediated inhibition in VTA DA neuron ﬁ ring can be mimicked by M-current opener (10 μ M retigabine) and blocked by M-current blocker (30 μ M XE991). In addition, enhancement of neuronal cAMP by forskolin (10 μ M) reduced M-current and increased DA neuron ﬁ ring rate. Finally, pharmacolog-icalblockofsynaptictransmissionbyNBQX(10 μ M),D-APV(50 μ M)andpicrotoxin(100 μ M)inVTAslicesfailed to prevent CB 2 R-mediated inhibition, while intracellular infusion of guanosine 5'-O-2-thiodiphosphate (600 μ M, GDP-β -S) through recording electrode to block postsynaptic G-protein function prevented JWH133-induced reduction in AP ﬁ ring. Interpretation: Our results suggest that CB 2 Rs modulate VTA DA neuron excitability mainly through an intrinsic mechanism, including a CB 2 R-mediated reduction of intracellular cAMP, and in turn enhancement of M-type K + currents. Fund:
Physicochemical Characterization and Sugar Profile of Argentinian Honeys from the Phytogeographic Provinces Paranaense and Pampeana in Misiones

The characterization of honeys from the Biomes and vegetation units of the Phytogeographical Provinces (PP) located in the Province of Misiones (Argentina) was performed by analysis of sugar profile and physicochemical parameters (Free Acidity, pH, Electrical Conductivity (EC), colour and contents of moisture, ash, total soluble solids and hydroxymethylfurfural) used for quality control of honey. The honeys analysed were authentic and traceable, and met the specifications of the national and/or international standards for the evaluated parameters, denoting blossom origin and confirming high quality, maturity and freshness. The influence of biome and Vegetation Units (VU) on physical and chemical parameters of the studied honeys was defined regarding both flora and pedoclimatic conditions. Honeys from VU-27 presented significantly higher contents of fructose, ash and total soluble solids, pH and EC and lower moisture content than those from VU-3. To the authors’ best knowledge, sugar profiles, free acidity and contents of ash and total soluble solids in honeys from the different PPs, vegetation units and Biomes of Misiones are reported for the first time. This study contributes to the classification of honeys from Misiones, helping to increase added value and access new markets.
Heritability of Autism Spectrum Disorder in a UK Population-Based Twin Sample.

IMPORTANCE Most evidence to date highlights the importance of genetic influences on the liability to autism and related traits. However, most of these findings are derived from clinically ascertained samples, possibly missing individuals with subtler manifestations, and obtained estimates may not be representative of the population. OBJECTIVES To establish the relative contributions of genetic and environmental factors in liability to autism spectrum disorder (ASD) and a broader autism phenotype in a large population-based twin sample and to ascertain the genetic/environmental relationship between dimensional trait measures and categorical diagnostic constructs of ASD. DESIGN, SETTING, AND PARTICIPANTS We used data from the population-based cohort Twins Early Development Study, which included all twin pairs born in England and Wales from January 1, 1994, through December 31, 1996. We performed joint continuous-ordinal liability threshold model fitting using the full information maximum likelihood method to estimate genetic and environmental parameters of covariance. Twin pairs underwent the following assessments: the Childhood Autism Spectrum Test (CAST) (6423 pairs; mean age, 7.9 years), the Development and Well-being Assessment (DAWBA) (359 pairs; mean age, 10.3 years), the Autism Diagnostic Observation Schedule (ADOS) (203 pairs; mean age, 13.2 years), the Autism Diagnostic Interview-Revised (ADI-R) (205 pairs; mean age, 13.2 years), and a best-estimate diagnosis (207 pairs). MAIN OUTCOMES AND MEASURES Participants underwent screening using a population-based measure of autistic traits (CAST assessment), structured diagnostic assessments (DAWBA, ADI-R, and ADOS), and a best-estimate diagnosis. RESULTS On all ASD measures, correlations among monozygotic twins (range, 0.77-0.99) were significantly higher than those for dizygotic twins (range, 0.22-0.65), giving heritability estimates of 56% to 95%. The covariance of CAST and ASD diagnostic status (DAWBA, ADOS and best-estimate diagnosis) was largely explained by additive genetic factors (76%-95%). For the ADI-R only, shared environmental influences were significant (30% [95% CI, 8%-47%]) but smaller than genetic influences (56% [95% CI, 37%-82%]). CONCLUSIONS AND RELEVANCE The liability to ASD and a more broadly defined high-level autism trait phenotype in this large population-based twin sample derives primarily from additive genetic and, to a lesser extent, nonshared environmental effects. The largely consistent results across different diagnostic tools suggest that the results are generalizable across multiple measures and assessment methods. Genetic factors underpinning individual differences in autismlike traits show considerable overlap with genetic influences on diagnosed ASD.
Quantification des contributions aux écoulements dans un bassin englacé par modélisation glacio-hydrologique. : Application à un sous-bassin de la Dudh Koshi (Népal, Himalaya).

Dans un contexte de recul des glaciers cause par le changement climatique et d'augmentation des besoins en eau due a l'accroissement de la population et au developpement economique, quantifier les contributions a l'origine des ecoulements dans les bassins versants de montagne himalayens est necessaire a la gestion de la ressource en eau actuelle ainsi qu'a la recherche de solutions d'adaptation aux impacts du changement climatique.La modelisation hydrologique est un outil adapte a la comprehension du fonctionnement des bassins versants de montagne cependant, le manque de donnees meteorologique dans les regions de haute altitude et la representation simplifiee des processus cryospheriques dans les modeles hydrologiques induisent de fortes incertitudes sur la simulation des debits dans les rivieres.Cette these vise a quantifier les differentes contributions aux ecoulements ainsi que leurs variations saisonnieres a l'echelle locale en appliquant un modele glacio-hydrologique dans un bassin englace de l'Himalaya nepalais.Une nouvelle parametrisation de l'albedo de la neige et de la fonte des glaciers couverts ainsi qu'une implementation d'un module d'avalanche sont ajoutes dans le modele DHSVM-GDM pour ameliorer la simulation du couvert neigeux et de l'evolution des glaciers.L'analyse du bilan hydrologique simule avec la nouvelle configuration du modele montre que les glaciers jouent un role important sur les debits a l'exutoire, notamment en hiver ou les debits sont principalement controles par l'ecoulement de l'eau liquide stockee dans les glaciers.Cette these met en relief la difficulte de quantifier la contribution des glaciers dans les debits de riviere, en effet, sur le bassin etudie, cette contribution est estimee a 45 % de l'ecoulement total si on considere la part des ecoulements issus de la fonte de glace, ou bien a 70 % si on considere la part des ecoulements provenant des zones englacees.L'incertitude des resultats de modelisation est etudiee en evaluant les impacts de la representation des processus dans le modele et de l'incertitude des donnees de forcage sur la simulation des contributions aux ecoulements.L'incertitude sur la surface englacee dans le bassin genere une incertitude de 20 % sur le volume de fonte de glace simule et l'incertitude sur les donnees de precipitations aboutit a une estimation de la contribution de la fonte de glace aux ecoulements est comprise entre 28 et 70 % des debits annuels.
UNSPAT: Uncertainty-Guided SpatioTemporal Transformer for 3D Human Pose and Shape Estimation on Videos

We propose an efficient framework for 3D human pose and shape estimation from a video, named Uncertainty-Guided SpatioTemporal Transformer (UNSPAT). Unlike previous video-based methods that consider temporal relationships with global average pooled features, our approach incorporates both spatial and temporal dimensions without compromising spatial information. We address the excessive complexity of spatiotemporal attention through two modules: Spatial Alignment Module (SAM) and Space2Batch. The modules align input features and compute temporal attention at every spatial position in a batch-wise manner. Furthermore, our uncertainty-guided attention re-weighting module improves performance by diminishing the impact of artifacts. We demonstrate the effectiveness of the UNSPAT on widely used benchmark datasets and achieve state-of-the-art performance. Our method is robust to challenging scenes, such as occlusion, and cluttered backgrounds, showing its potential for real-world applications.
The continuance intention of users toward mobile assisted language learning: The case of DuoLingo

: Recently, mobile learning has become a potential approach in education due to its use inside and/or outside the classroom. Considering that the majority of mobile device users are 18-29 years old higher education students and English is the predominant language of the internet, this study aimed to predict the continuance intention of users toward mobile-assisted language learning (MALL) after fourteen weeks experience on a mobile application, namely Duolingo. To do this, we used the Technology Acceptance Model, Theory of Planned Behavior and Expectation Confirmation Model. The participants were 379 students taking the course English I. This cross-sectional survey study revealed that perceived behavioral control, attitude, subjective norms, satisfaction, and perceived usefulness have a significant effect on the university students’ continuance intention to use MALL. In turn, it validated our proposed model on the continuance intention to use MALL. Based on the results of this study, some practical and theoretical implications were discussed.
Active Transfer Learning for Efficient Video-Specific Human Pose Estimation Supplementary Material

This supplementary material covers the additional re-sults and visualizations that were excluded from the main paper due to a lack of space. Specifically, the following contents are included: i) The complete table of our experiment results in the main paper, the impact of hyperparam-eter changes in our proposed method, and the validation of proposed uncertainty criteria (Sec. A). ii) The experimental results of video-specific ATL on JRDB-Pose (Sec. B), iii) A statement about the limitations of the proposed method (Sec. C), and iv) Additional qualitative examples of sample selection by proposed THC, WPU, and DUW (Sec. D).
Chemical changes of in-package microwave-treated dhap khoa during storage

In-package microwave-treated dhap khoa (a heat-desiccated milk product) was investigated to determine chemical changes during its storage at different temperatures. An optimized sample of dhap khoa packed in a polypropylene pack was stored at 10, 35 and 45 °C temperatures. The changes in Hydroxymethylfurfural (HMF), Thiobarbituric acid (TBA)
ISMIP6-based Antarctic Projections to 2100: simulations with the BISICLES ice sheet model

The contribution of the Antarctic ice sheet is one of the most uncertain components of sea level rise to 2100. Ice sheet models are the primary tool for projecting future sea level contribution from continental ice sheets. The Ice Sheet Model Intercomparison for the Coupled Model Intercomparison Phase 6 (ISMIP6) provided projections of the ice sheets contribution to sea level over the 21st century. It quantified uncertainty due to ice sheet model, climate scenario, forcing climate model and uncertain model parameters. We present simulations following the ISMIP6 framework with the BISICLES ice sheet model, 5 alongside new experiments extending the ISMIP6 protocol to more comprehensively explore uncertain ice sheet processes. These results contributed to Antarctic projections of Edwards et al. (2021), which formed the basis of sea level projections for the Sixth Assessment Report of the Intergovernmental Panel on Climate Change (AR6). The BISICLES experiments presented here show the important interplay between surface mass balance forcing and ocean driven melt, with high warming, high accumulation forcing conditions leading to mass gain (negative sea level contribution) under low sensitivity to ocean driven 10 melt. Conversely, we show that when sensitivity to ocean warming is high, ocean melting drives increased mass loss despite high accumulation. Finally, we show that collapse of ice shelves due to surface warming increases sea level contribution by 25 mm for both moderate and high sensitivity of ice shelf melting to ocean forcing tested.
Neural correlates of inspection time: the tactical role of P3b

Both P3b and Inspection Time Task (ITT) are related with intelligence, yet their relationships have not been well addressed. This event-related potential study sought to address this question with four levels of discriminative stimulus duration, and further tried to shed lights on the long controversial subject about what psychological process is associated with P3b. Participants (N=25) were asked to perform this ITT while undergoing 64-channel EEG recording. A Tapping task and four Elementary Cognitive Tests (ECTs), including a Simple Reaction Time (SRT), 2 Choice Reaction Time task (CRT), and a Pattern Discrimination task (PD), were included. N1, P1, and P3b at Pz were analyzed. Results showed that the P3b latency signiﬁcantly prolonged with the increase of ITT duration. More intriguingly, the P3b latencies was negatively correlated with ITT accuracies but positively correlated with the RTs of the SRT, but only in the 34 ms condition. No signiﬁcant correlation was found between the P3b latencies and the RTs of other ECTs or the Tapping task. Our results indicate that those who are able to accurately perceive and process very brieﬂy presented stimuli have a higher information processing speed reﬂected by P3b latency, which is likely a reﬂection of mainly bottom-up process to form a perceptual memory and a decision. We conclude that these results support Verleger et al.’s view that P3b elicited by ITT, at least in the early stage, is more related with tactical processing that marks the closure of a perceptual epoch, rather than strategic processing or metacognition.