Miracle-dz/UniFAR-FTUs huggingface dataset:
Effect of Abiotic Climatic Factors on the Gonadal Maturation of the Biocontrol Agent Sphaerophoria rueppellii (Wiedemann, 1830) (Diptera: Syrphidae)

Simple Summary Knowledge about the morphology and functioning of the male and female reproductive system in insects is key to understanding their reproductive biology, and to assessing the effects that environmental factors, such as temperature or photoperiod, can have on oviposition, fecundity, and lifespan. This knowledge is particularly interesting in those species that are mass-reared, as in the case of the predatory syrphid Sphaerophoria rueppellii. Given the lack of published information regarding sexual maturation in syrphids, this type of study, applied to beneficial insects used as biological control agents, offers, firstly, the chance to improve their mass breeding under controlled conditions and, secondly, to know their capability for pest control response under field conditions. Our results show that photoperiod and temperature affect development and gonad maturation in S. rueppellii males and females. Abstract The hoverfly Sphaerophoria rueppellii is currently one of the most effective predators commercially available for aphid pest control. However, knowledge of the reproductive system of males and females of this syrphid is limited. The present article aims to report how changes in the temperature and photoperiod may affect development of the gonads (ovaries and testes), oviposition, and fecundity during the lifespan of S. rueppellii. Four environmental conditions (14L:10D, T: 20 ± 1 °C; 12L:12D, T: 20 ± 1 °C; 14L:10D, T: 25 ± 1 °C; and 12L:12D, T: 25 ± 1 °C) were used to determine oviposition, hatching percentage, and lifespan during a period of 30 days after the adult emergence. The maturation of the ovaries was done under three treatments (barley leaves with aphids always available; barley leaves two days per week with aphids available; no barley leaves available), and in the same environmental conditions noted above. Males at 14L:10D, 20 ± 1 °C; and 14L:10D, 25 ± 1 °C; were used to analyze and study the maturation of the testes. Females at 14L:10D; T: 25 ± 1 °C showed a significant difference in oviposition, percentage of hatching, and rate of eggs. A detailed description of the male and female gonads was undertaken, and it was determined that the conditions in which males sexually mature early are at 14L:10D, 25 ± 1 °C. These results will improve the application of S. rueppellii in crops, for the control of aphid pests.
A Consistent Framework for Coupling Basal Friction With Subglacial Hydrology on Hard‐Bedded Glaciers

Below hard‐bedded glaciers, both basal friction and distributed subglacial drainage are thought to be controlled by a network of cavities. Previous coupled hydro‐mechanical models, however, describe cavity‐driven friction and hydraulic transmissivity independently, resulting in a physically inconsistent cavity evolution between the two components of the models. Here, we overcome this issue by describing the hydro‐mechanical system using a common cavity‐evolution description, that governs both transient friction and hydraulic transmissivity. We show that our coupling approach is superior to previous formulations in explaining a unique observation record of glacier sliding speed from the French Alps. We find that, at multi‐day to multi‐decadal timescales, sliding speed can be expressed as a direct function of basal shear stress and water discharge, without accounting for water pressure, which simply adjusts to maintain the cavitation ratio needed to accommodate the water supply.
Effect of Career Development Module (CDIM) on Students’ Career Maturity and Decision Making in Saudi Arabia

Human development tasks must be geared toward achieving career planning for adolescents' future careers. Career planning is an important part that will determine the success of adolescents’ future lives. This study examines the impact of a career development intervention module on high school students’ career maturity and decision-making in Saudi Arabia. A quasi-experimental design involving pre-test and post-tests was adopted using forty respondents randomly selected from each of the two high schools assigned into experimental and control groups. Two sets of questionnaires were adopted and used for data collection. An independent t-test showed that a career development intervention module has a significant effect on Saudi high school students’ career maturity and career decision-making. Thus, the career development intervention module significantly improved students’ maturity in career choice and decision-making for future life. As a result, professional career training should be designed around this model to provide counselors with the skills needed to help high school students in Saudi Arabia make better career choices.
Effect of Prior International Experience on Cultural Intelligence Level and Cross-Cultural Adjustment Among Temporary Project Team

Globalisation is no longer a new phenomenon in recent years. Many businesses employ eligible expatriates to work in their organisations, including the construction sector. The ability of an expatriate to adapt effectively across cultures is commonly referred to as cultural intelligence (CQ) and cross-cultural adjustment (CCA). Both are cited as essential factors for expatriate performance in the international workplace. Nevertheless, the interrelationship between the CQ of the international construction project team and CCA has mostly been ignored. Hence, this study intended to explore the correlation between CQ and CCA levels among construction expatriates and further investigated the effect of prior international experience on their CQ and CCA level. Spearman rank correlation and Mann-Whitney U test were conducted on the 191 responses accepted. The results revealed their CQ has positively and significantly correlated with CCA, i.e. general, work and interaction, particularly in motivational CQ. Moreover, expatriates' prior international experience in the study domain could lead expatriates to a lower CQ and a lower adjustment level. Respondents with prior international work experience had a higher CQ level. However, the longer the period of previous international work experience, the weaker the cognitive CQ and behavioural CQ. This study can contribute to the predictors affecting the outcome of international assignments that can be employed to select the right applicants to fit into a multicultural project team in the construction industry.
Loop Diuretics Are Associated with Increased Risk of Hospital-Acquired Acute Kidney Injury in Adult Patients: A Retrospective Study

Background: The association between loop diuretics and acute kidney injury (AKI) remains unclear. Methods: The population studied was selected from the Epidemiology of AKI in Chinese Hospitalized patients (EACH) study. Exposure to loop diuretics was defined as any filled prescription prior to the date when AKI was detected in patients with HA-AKI, and prior to the last date of SCr testing in those without AKI. The outcome was AKI, defined by the Kidney Disease Improving Global Outcomes criteria. Associations between loop diuretics and HA-AKI were examined by Cox proportional hazards models adjusted for baseline and time-dependent covariates. Results: Of the 150,020 patients, 16,437 (11.0%) were prescribed loop diuretics, and 5717 (3.8%) experienced HA-AKI events. The crude rates of HA-AKI in patients who were and were not prescribed loop diuretics were 1632 (9.9%) and 3262 (2.8%), respectively. A multivariate cox proportional hazards analysis showed that exposure to loop diuretics was associated with significantly increased risks of HA-AKI compared with non-users (hazard ratio (HR), 1.61; 95% CI (confidence interval), 1.55–1.67), other diuretics (HR, 1.09; 95% CI, 1.03–1.15), and osmotic diuretics (HR, 1.30; 95% CI, 1.20–1.42). Compared with other diuretics, the use of loop diuretics was associated with higher risks of HA-AKI in women, in patients without hypertension, in patients without heart failure, in patients without liver cirrhosis, and in patients not requiring surgery. Conclusions: Loop diuretics are widely used and are associated with increased risks of HA-AKI in hospitalized adults. Renal function should be more closely monitored during the use of loop diuretics.
Verification of Mechanical Properties of Historical Brick Masonry Walls with Masonry Quality Index Method in Iran

ABSTRACT Identification of mechanical characteristics of the materials used in heritage constructions is one of the most important steps in their seismic assessment, which may be determined through destructive, semi-destructive (or minor destructive) and non-destructive tests. Due to the fact that destructive and semi-destructive testing on heritage buildings is often impossible, Italian researchers have proposed a qualitative method called the masonry quality index to estimate the mechanical properties of heritage building materials. In this article, the MQI method has been validated in seven different historical buildings in Qajar dynasty period dating back to 1785–1925 A.D. The results were compared to those of double flat jack tests performed with permission from the Ministry of Cultural Heritage, Tourism and Handicrafts in Iran. The compressive strength and elastic modulus for brick masonry were in the range of 0.4–2.5 MPa and 650–4150 MPa, respectively. In addition, two equations were presented to estimate the compressive strength and elastic modulus of historical masonry walls without the need for performing minor destructive in-situ tests.
Family Climate in Nurturing Individuals’ Self-Concept: A Qualitative Study

In general, family has a significant influence on how individuals form their self-evaluations because they form their primary self-concepts in their familial context, which serves as a foundation for secondary self-concepts formed through relationships outside the family. Therefore, this paper aims to focus on the influence of family climate in nurturing individuals’ self-concept. This study obtained the data from qualitative research for the doctoral degree of one of the authors and involved 46 millennial respondents who lived in Malaysia. The Google Forms (Docs) have been utilised in conducting a web-based written interview from May to July 2021. By referring to the feedback of the respondents, this study found the family climate influenced the self-concept of the individuals in five aspects, which are in terms of their ideology, education, character building, religious belief, and political belief. This study believes that the identification of the influence of family climate toward the self-concept of their family members allows more opportunities for them to improve their families’ significant responsibilities in helping their children build and refine their positive self-concept. As a result, key qualities and characteristics of good citizenship are promoted at the individual, interpersonal and societal levels.
Renal Cell Carcinoma: A Complex Therapeutic Challenge in the Elderly

An increase in age and the occurrence of renal cell carcinoma have been positively correlated. A strict therapeutic protocol for early diagnosis, screening, prevention, and population awareness needs to be well-established as a rationale to approach the morbidity at a treatment-eligible phase in the aged. Genetic predisposition appears to have a minor role in the disease pathology. Imaging modalities, providing high-resolution images of the tumor, have undoubtedly benefitted the diseased subset in aiding the diagnosis, however, a preliminary guideline protocol for its early implication in concordance with the initial symptoms needs to be adopted. Burdening of the geriatric age group by concomitant co-morbidities further deteriorates the devastating effects of the primary tumor, which, in total, appear to evolve as a final, complex stage of the illness in the majority, leading to an eventual high mortality rate. Despite being a challenging task for managing the tumor, age should not be considered the sole treatment barrier for approaching the disease.
New Peptide Functionalized Nanostructured Lipid Carriers with CNS Drugs and Evaluation Anti-proliferative Activity

Nanoparticulate systems have been widely investigated as delivery vectors for efficient drug delivery in different diseases. Nanostructured lipid carriers (NLC) are composed of both solid and liquid lipids (glyceryl dibehenate and diethylene glycol monoethyl ether) and have demonstrated enhanced biological compatibility and increased drug loading capability. Furthermore, the use of peptides, in particular cell-penetrating peptides, to functionalize nanoparticles and enhance cell membrane permeation was explored in this paper. In this paper, we described the synthesis of a new conjugated of tranylcypromine with MAP. In addition, taking into consideration our previous results, this study developed different NLCs loaded with three central nervous system (CNS) drugs (tacrine (TAC), rasagiline (RAS), and tranylcypromine (TCP)) functionalized with model amphipathic peptide (MAP) and evaluated their activity against cancer cells. Particle size analysis demonstrated NLC presented less than 200 nm and a polydispersity index less than 0.3. Moreover, in vitro results showed that conjugation of MAP with drugs led to a higher decrease in cell viability of a neuroblastoma cell line and Caco-2 cell line, more than MAP alone. Furthermore, NLC encapsulation contributed to higher cellular delivery and enhanced toxic activity at lower concentrations when compared with free or co-administration drug-MAP conjugate.
Probing the Flipped Learning Literature in Social Sciences and Humanities Education

was the main focused filed in the employment of flipped learning compared to others. In addition, it was seen that the majority of the flipped learning studies included first year's students as the study level. Meanwhile, the most significant challenges encountered by students and instructors is the activities design depending on the technology being used and limited resources and time. The results revealed that the flipped learning is an effective approach in promoting positive outcomes and the needed century skills. Collaborative research amongst countries on the effect of flipped learning in the future studies to produce more complete findings.
Moderation of the Association between Primary Language and Health by Race and Gender: An Intersectional Approach

In the United States (US), limited English proficiency is associated with a higher risk of obesity and diabetes. “Intersectionality”, or the interconnected nature of social categorizations, such as race/ethnicity and gender, creates interdependent systems of disadvantage, which impact health and create complex health inequities. How these patterns are associated with language-based health inequities is not well understood. The study objective was to assess the potential for race/ethnicity, gender, and socioeconomic status to jointly moderate the association between primary language (English/Spanish) and having obesity and diabetes. Using the 2018 Behavioral Risk Factor Surveillance System (n = 431,045), weighted generalized linear models with a logistic link were used to estimate the associations between primary language (English/Spanish) and obesity and diabetes status, adjusting for confounders using stratification for the intersections of gender and race/ethnicity (White, Black, Other). Respondents whose primary language was Spanish were 11.6% more likely to have obesity (95% CI 7.4%, 15.9%) and 15.1% more likely to have diabetes (95% CI 10.1%, 20.3%) compared to English speakers. Compared to English speakers, Spanish speakers were more likely to have both obesity (p < 0.001) and diabetes (p < 0.001) among White females. Spanish speakers were also more likely to have obesity among males and females of other races/ethnicities (p < 0.001 for both), and White females (p = 0.042). Among males of other racial/ethnic classifications, Spanish speakers were less likely to have both obesity (p = 0.011) and diabetes (p = 0.005) than English speakers. Health promotion efforts need to recognize these differences and critical systems–change efforts designed to fundamentally transform underlying conditions that lead to health inequities should also consider these critical sociodemographic factors to maximize their effectiveness.
Muscle and Adipose Tissue Communicate with Extracellular Vesicles

In numerous body locations, muscle and adipose tissue are in close contact. Both tissues are endocrine organs that release cytokines, playing a crutial role in the control of tissue homeostasis in health and diseases. Within this context, the identification of the signals involved in muscle–fat crosstalk has been a hot topic over the last 15 years. Recently, it has been discovered that adipose tissue and muscles can release information embedded in lipid-derived nanovesicles called ‘extracellular vesicles’ (EVs), which can modulate the phenotype and the homeostasis of neighboring recipient cells. This article reviews knowledge on EVs and their involvement in the communication between adipose tissue and muscle in several body locations. Even if the works are scarce, they have revolutionized our vision in the field of metabolic and cardiovascular diseases.
NSS_A_256987 509..524

Ying Huang Steve Hennig Ingo Fietze Thomas Penzel 1,2 Christian Veauthier 1 1Interdisciplinary Center of Sleep Medicine, Charité University Medicine Berlin, Berlin 10117, Germany; 2Department of Biology, Saratov State University, Saratow, Russia Background: Sleepiness at the wheel affects 10% to 15% of drivers and is one major cause of death on highways with one-third of fatal accidents. Obstructive sleep apnea (OSA) is one of the most common sleep disorders leading to sleepiness at the wheel. The aim of this study was to compare the psychomotor vigilance test reaction time (PVT RT) in OSA patients and controls (morning and afternoon) with the results of a divided attention steering simulator (DASS). A second purpose was to compare these results with the mean sleep latencies in the multiple sleep latency test (MSLT), the Epworth Sleepiness Scale (ESS) values and a neurocognitive test (test of attentional performance, TAP). Patients and Methods: Thirty eight OSA patients and 16 age and sex matched healthy controls were investigated by ESS, PVT, TAP, MSLT, and DASS (response time, failed responses, lane deviation, and off-road-events). Results: With increasing age, the performance in the DASS decreased. There was no correlation between the DASS and the results of the MSLT and ESS. The controls showed a significantly faster DASS response time in the morning compared to OSA patients (median 2.1 versus 3.0; p=0.044) and fewer off-road events (9 versus 37; p=0.042). We found a moderate correlation between the PVT RT and all parameters of the DASS, as well as the TAP “alertness” subtest. Conclusion: The increase of PVT RT as well as the decreased tonic alertness in the TAP in untreated OSA patients correlated with an impairment of simulated driving performance. The PVT and the TAP are both suitable diagnostic tools for measuring impaired driving ability in OSA patients. The MSLT did not correlate with the simulated driving performance. We recommend investigation of a longer version of the PVT in order to increase its sensitivity.
Single Nucleotide Variants Associated with Colorectal Cancer Among Iranian Patients: A Narrative Review and

: Colorectal cancer has been considered as one of the complicated multi-stage processes after adenoma-carcinoma sequence. Therefore, studies of the molecular dysregulation basis could present information on the recognition of the potent biomarkers and treatment targets for this disease. Even though outcomes of the patients with colorectal cancer have been improved largely with current annual screening plans, it is necessary to have reliable prognostic biomarkers because of the disease heterogeneity. There is a signi ﬁ cant relationship between SNP in IL1RN* 2 (IL1ra), − 509 C/T (TGFB1), rs11556218 T>G and rs4778889 T/C (IL16), miRNA-binding site polymorphisms in IL16, rs4464148 (SMAD7), rs6983267 (EGF), GSTT1, TACG haplotype (CTLA4), 1793G> A (MTHFR), Leu/Leu genotype of (EXO1), − 137 G/C (IL18), C/T genotype (XRCC3), I3434T (XRCC7), MGMT, C3435T (MDR1), ff genotype of FokI, 677CT+TT (MTHFR), G2677T/A (MDR1) and CRC. Increased risk has been observed in VDR ApaI genotype “ aa ” . Finally, the protective effect has been explored in the TACA haplotype (CTLA4). According to the ﬁ ndings, the genetic polymorphisms in the immunity-associated genes are related to the CRC amongst the Iranian patients. Therefore, more large-scale functional investigations are necessary for con ﬁ rming the results.
Family-Supportive Supervisor Behaviors and Psychological Distress: A Secondary Analysis across Four Occupational Populations

This study assessed the associations of employee’s perceptions of family-supportive supervisor behaviors (FSSB) and their psychological distress across four occupational populations (n = 3778): Information technology; healthcare; military-connected Veterans; and National Guard service members. Data were gathered and analyzed from four larger archival datasets to compare differences in these relationships. Results revealed significant negative relationships between employee reports of FSSB and their psychological distress within occupations, as expected. Furthermore, results revealed significant differences across occupational populations for employee reports of both FSSB and psychological distress. Hierarchical moderated multiple regression analyses were conducted to examine the extent of these mean differences across groups. Results revealed significant differences among these four groups such that the military-connected Veteran employees demonstrated significantly stronger associations of FSSB, and psychological distress compared to the other three occupations of information technology, healthcare, and National Guard service members. These findings suggest the importance of FSSB to worker psychological health across a variety of occupational populations, specifically noting the importance and presence of FSSB for Veteran employees’ psychological distress in civilian workplaces. Practical implications include the need for training leaders on how to better support employees’ work and non-work lives, mental health, and well-being.