Miracle-dz/UniFAR-FTUs huggingface dataset:
Management of patients who deliberately harm themselves

Deliberate self harm is a behaviour not an illness. It is defined as any act by an individual with the intent of harming himself or herself physically and which may result in some harm. Deliberate self harm has also been called “attempted suicide” or “parasuicide. ” Although attempted suicide should be restricted to cases where a fatal intent can be assumed, these terms are often used synonymously. Suicide is the subcategory with a fatal outcome. #### Summary points Patients who deliberately harm themselves should be assessed as comprehensively and thoroughly as possible, including the risk for suicide A multidisciplinary team approach to assessment and management is optimal A psychiatrist should be involved in the evaluation Management should be individualised on the basis of the assessment; mostly treatment for associated psychiatric disorders and assistance with precipitating circumstances Patients accepting offers for help should be followed up quickly Typically 10-30 per 100 000 people commit suicide annually. Deliberate self harm that is non-fatal may be 10-20 times more frequent. Both fatal and non-fatal deliberate self harm constitute considerable public health problems regarding both individual suffering and costs to society. The motivations behind acts of deliberate self harm vary. One motivation may be a wish to die. Deliberate self harm may also constitute a more or less dysfunctional way of achieving wanted changes of life—for example, escape, attention, manipulation of others. The intent in each person is complex and ambivalent. Although some aspects of suicidal behaviour might be interpreted as rational, the behaviour is contrary to basic biological principles of survival. Therefore it may be postulated that some link in the individual's perception, cognitive and emotional processing, and behaviour is disordered—that is, a psychiatric disorder. This is corroborated by empirical studies. In a two year Swedish study of 812 consecutive patients who had deliberately harmed themselves, 11% …
Eﬀicient Composition for Virtual Camera Control

Automatically positioning a virtual camera in a 3D environment given the speciﬁcation of visual properties to be satisﬁed (on-screen layout of subjects, vantage angles, visibility) is a complex and challenging problem. Most approaches tackle the problem by expressing visual properties as constraints or functions to optimize, and rely on computationally expensive search techniques to explore the solution space. We show here how to express and solve the exact on-screen positioning of two or three subjects using a simple and very efﬁcient technique. We express the solution space for each couple of subjects as a 2D manifold surface. We demonstrate how to use this manifold surface to solve Blinn’s spacecraft problem with a straightforward algebraic approach. We extend the solution to three subjects and we show how to cast the complex 6D optimization problem tackled by most contributions in the ﬁeld in a simple 2D optimization on the manifold surface by pruning large portions of the search space. The result is a robust and very efﬁcient technique which ﬁnds a wide range of applications in virtual camera control and more generally in computer graphics.
ORIGINAL STUDY Role of Pulsed Radiofrequency in Management of Chronic Discogenic Lumbosacral Radicular Pain

Background data: Lumbosacral radicular pain is the most common neuropathic pain and is secondary to multiple pathologies, mostly disc herniation. Despite conservative treatment, about 10% of patients still suffer from chronic pain. Previous clinical studies reported promising results of using pulsed radiofrequency (PRF) for 2 e 4 min. Purpose: This study aims to evaluate the ef ﬁ cacy and safety of (PRF) for 8 min in managing chronic discogenic lumbosacral radicular pain. Study design: A prospective descriptive clinical case series. Patients and methods: This study was conducted on 30 patients with lumbosacral discogenic radicular pain diagnosed clinically and radiologically. All patients underwent PRF for corresponding dorsal root ganglia for 8 min under ﬂ uo-roscopy with 1, 3-, and 6-month postprocedural follow-up regarding pain relief using the numerical rating scale (NRS). The patient satisfaction index (PSI) was used to assess the outcomes and responses to PRF 6 months after the procedure, and all results were analyzed. Results: The preprocedural mean NRS was 7.7, which dropped after the procedure at 1, 3-, and 6-month follow-up to 2.7, 2.8, and 3, respectively. Therefore, the average improvement at the 6-month follow-up was 4.7, which means a 61% average decline of the mean NRS of pain intensity after PRF at the 6-month follow-up. The success of PRF, as de ﬁ ned by at least a 50% reduction of NRS, was 90%, 86.7%, and 80% after 1, 3-, and 6-month follow-ups, respectively ( P -value ¼ 0.001). The most important factor predicting the outcome was the degree of nerve root compression ( P -value ¼ 0.002). Conclusion: Pulsed radiofrequency for 8 min is a safe and effective minimally invasive procedure in the short-term management of chronic lumbosacral discogenic radicular pain, especially in mild and moderate nerve root compression.
Oh in the Coastal Boundary Layer of Crete during Minos Oh in the Coastal Boundary Layer of Crete during Minos: Measurements and Relationship with Ozone Photolysis Acpd Oh in the Coastal Boundary Layer of Crete during Minos

Hydroxyl radical (OH) concentrations were measured in August 2001 at Finokalia Station on the northeastern coast of Crete during the Mediterranean Intensive Oxidant Study (MINOS). OH was measured based on selected ion chemical ionization mass spectrometry (SI/CIMS) with a time resolution of 30 s and signal integration of 5 min.
THE IMPACT OF TOURIST’S INTENTION TO USE WEB 3.0: A CONCEPTUAL INTEGRATED MODEL BASED ON TAM & DMISM

The rapid revolution of information technology has enhanced the global tourism industry that positively changed the structure of economy in large scale. Today, tourists face difficulties to find information to meet their needs or exceed their expectations due to the huge amount of information in the current Web and tourism portals. This has made the tourists or travelers decision to visit a particular destination very difficult. The main purpose of this research is to propose a conceptual integrated model to determine the factors influencing tourist’s intentions to use Web3.0. Therefore, despite the enormous transformative innovation that the Web3.0 will provide, there is still a significant gap between the current applied systems and the new technology at this moment. Besides that, the literature has shown that there are only few publications that used integrated theoretical model of Technology Acceptance Model (TAM) and Delone and Mclean Information System Model (DMISM) to investigate tourist’s intention to use new technology particularly Web 3.0. In addition, this research not only defines Web3.0, but also determines the possible challenges, risks, and opportunities that are emerged from Web3.0 technology specifically in the tourism domain. Moreover, while Web3.0 is prominent across businesses, there is surprisingly very limited academic work devoted to study its effect on consumer’s intentions to use and the tourism industry is not an exception. Consequently, this study will provide more insights, advance our understanding and contribute to this growing area of research as well as the proposed integrated conceptual model can serve as fundamental framework to be used in different domains.
FACTORS THAT INCREASE INTEREST IN USING MUTUAL FUND APPLICATION WITH USER ACCEPTANCE APPROACHES

There are many online investment applications that are not registered to OJK (Financial Service Authority) so that the legality of the application does not exist. This legality makes the credibility of other online investment applications highlighted. Credibility affects the intention to use an application. A mobile application success is also depending to intention to use. These issues should be highlighted because give direct impact both for legalized mutual fund application and the citizen. The purpose of this study is to determine the factors that affecting the intention to use mutual fund investment applications Bibit.id in the millennial generation. This Study use Technology Acceptance Model (TAM) that has modified by the Author. The modifications of Technology Acceptance Model using several external variables such as Financial Literacy, Trust, Social Influence, User Interface, User Experience. The results of the analyzed data show Financial Literacy, Perceived Ease of Use, Social Influence, User Experience, and Perceived Usefulness should be a consideration while develop the mutual fund application. In this research found Financial Literacy have positive impact to Intention to Use, more easily the application used makes the application more useful. The useful application affecting to intention to use. Social influence both working environment or family makes the application more easy to use. Users feel, the easier to use application better than the application interface.
W Capacity Expansion in the Integrated Supply Network for an Electricity Market

—Constraints in fuel supply, electricity generation and transmission interact to affect the welfare of strategic generators and price-sensitive consumers. We consider a mixed integer bilevel programming model in which the leader makes capacity expansion decisions in the fuel transportation, generation, and transmission infrastructure of the electricity supply network to maximize social welfare less investment cost. Based on the leader's expansion decisions, the multiple followers including the fuel suppliers, ISO and generation companies simultaneously optimize their respective objectives of cost, social welfare, and profit. The bilevel program is formulated as a mathematical program with complementarity constraints. The computational challenge posed by the discrete character of transmission expansions has been managed by multiple model reformulations. A lower bound provided by a nonlinear programming reformulation increases the efficiency of solving a binary variable reformulation to global optimality. A single-level optimization relaxation serves as a competitive benchmark to assess the effect of generator strategic operational behavior on the optimal capacity configuration.
Application of wetland waste plant biochar in combination with arbuscular mycorrhizal fungi on immobilization of Cd in contaminated soil

In this study, biochar pyrolyzed from different wetland waste plants (Reed, Typha, Canna) was used to immobilize Cd in contaminated soil. The results showed that biochar could all enhance the residual Cd 2+ in soil. Moreover, Ca500 (pyrolyzed at 500 ℃ from Canna) showed the best immobilization capacity due to its larger surface, higher number of pores and its regular, smooth structure. Optimum conditions for Ca-500 immobilization to Cd 2+ in soil were: amount 6% (wt%) and contacting time 16 weeks, the exchangeable and the state of bound to carbonates of heavy metals reduced 92.08% and 67.64%, respectively. After combining biochar with arbuscular mycorrhizal, the results showed that the combined system could more effectively reduce the transportable Cd content in soil, increase the proportion of residual Cd, effectively reduce the migration of Cd, improve the biomass and root length of vegetables, reduce Cd absorption by vegetables and the ability of vegetables to transfer Cd from root to the upper part, and reduce the edible safety risk. Simultaneously, biochar with arbuscular mycorrhizal can improve the antioxidant capacity of vegetables and their resistance to heavy metals, optimize the composition of soil microbial community, and improve soil microbial abundance and community β -diversity. It can also signi�cantly change the functional gene expression of soil microorganisms, soil fertility, and the self-healing ability to heavy metals.
THE ROLE OF EXPERIENCE AND SELF-EFFICACY IN THE TECHNOLOGY ACCEPTANCE MODEL: A STUDY CASE FOR PRACTITIONERS AND TRAINEES

The purpose of the current study is to estimate the factors stimulating the acceptance and use of information technology (IT) systems by practitioners and trainees. To solve this problem, the research has applied the technology acceptance model (TAM) - this model has been becoming one of the widely accepted research models in the field of IT applications. However, when conducting a comprehensive review of existing literature, it was found that the relationship results in TAM were inconsistent between the studies given the diversity of predictive factors in the TAM along with cultural differences. Therefore, this study attempts to suffice this gap by assessing the interaction factors in TAM with the e-learning context of working adults. The results show that experience, enjoyment, and self-efficacy affected learners' perceived usefulness and ease of use, which in turn affected the satisfaction and intent of the behavior. Therefore, this study has provided insight into how learners shape their attitudes and intentions for e-learning.
Dual Infrasound Sources from a Vulcanian Eruption of Sakurajima Volcano Inferred from Cross‐Array Observation

The study of volcano infrasound is becoming increasingly popular (Johnson and Ripepe, 2011; Fee and Matoza, 2013) with analysis of the recorded signals contributing to our understanding of eruption dynamics and enhancing capabilities in remote monitoring of volcanoes. Multiple studies have determined the source locations of the infrasound from volcanic eruptions. For example, Ripepe and Marchetti (2002) analyzed infrasound records for events occurring at Stromboli volcano. The authors successfully located different active vents in the craters to a horizontal resolution within a few tens of meters. Additionally, Jones and Johnson (2011) identified a migrating source of infrasound on the surface of the 200 m radius Santiaguito dome. Further from the vent region, infrasound signals are also generated by volcanic jet flow throughout the plume (Matoza et al. , 2009; Fee et al. , 2010). In these cases, large‐scale turbulent interactions within the volcanic plume are likely to be the source of infrasound waves. For these signals, the infrasound spectrum has a shape similar to that of man‐made turbulent jet noise (Tam et al. , 1996; Matoza et al. , 2009). It is plausible that infrasound waves recorded during volcanic eruptions are a composite signal generated by both processes at the vent/crater and within the eruption cloud itself. However, the source of infrasound is seldom constrained with sufficient spatial resolution to discriminate between signals at the vent or in the volcanic cloud. Determination of detailed infrasound source position and/or its time evolution during an eruption is a key research aim. In this paper, we investigate the locations of infrasound sources and reflections during vulcanian eruptions of Sakurajima volcano in Japan. Cyclic vulcanian eruptions and continuous open‐vent degassing characterize the recent activity of the Showa crater of Sakurajima volcano, which has been ongoing since June 2006 (Iguchi et al. , 2013). Total numbers of …
Edinburgh Research Explorer The genome-defence gene Tex19.1 suppresses LINE-1 retrotransposons in the placenta and prevents intra-uterine growth retardation in mice

DNA methylation plays an important role in suppressing retrotransposon activity in mammalian genomes, yet there are stages of mammalian development where global hypomethylation puts the genome at risk of retro-transposition-mediated genetic instability. Hypomethylated primordial germ cells appear to limit this risk by expressing a cohort of retrotransposon-suppressing genome-defence genes whose silencing depends on promoter DNA methylation. Here, we investigate whether similar mechanisms operate in hypomethylated trophectoderm-derived components of the mammalian placenta to couple expression of genome-defence genes to the potential for retrotransposon activity. We show that the hypomethylated state of the mouse placenta results in activation of only one of the hypomethylation-sensitive germline genome-defence genes: Tex19.1. Tex19.1 appears to play an important role in placenta function as Tex19.1 2 / 2 mouse embryos exhibit intra-uterine growth retardation and have small placentas due to a reduction in the number of spongiotropho-blast, glycogen trophoblast and sinusoidal trophoblast giant cells. Furthermore, we show that retrotrans-poson mRNAs are derepressed in Tex19.1 2 / 2 placentas and that protein encoded by the LINE-1 retrotransposon is upregulated in hypomethylated trophectoderm-derived cells that normally express Tex19.1 . This study suggests that post-transcriptional genome-defence mechanisms are operating in the placenta to protect the hypomethylated cells in this tissue from retrotransposons and suggests that imbalances between retrotransposon activity and genome-defence mechanisms could contribute to placenta dysfunction and disease.
Proximate, Antinutrient and Mineral Composition of Five Varieties (Improved and Local) of Cowpea, Vigna unguiculata, Commonly Consumed in Samaru Community, Zaria-Nigeria

In Nigeria, several improved varieties of cowpea have been developed, yet little effort has been made to ascertain their nutritional advantage over local varieties, hence the need for this research. In this work, five varieties of cowpea (which include two local and three improved varieties) consumed in Samaru community, Zaria-Nigeria were analyzed for their proximate composition, antinutrients and mineral contents. The results shows that IAR48 an improved variety has significantly higher (p 0.05) between the five varieties. In conclusion, the result of this research suggests that the improved varieties are indeed better than the local varieties.
Di V erential expression of thyroid hormone receptor isoforms is strikingly related to cardiac and skeletal muscle phenotype during postnatal development

The genomic actions of thyroid hormones (THs) are mediated by receptors (TRs) that are encoded by two protooncogenes, c-erb A-Æ and c-erb A-(cid:226) . The precise functions of the TR isoforms are unclear and this study focuses on the potential roles of the TR Æ and TR (cid:226) isoforms in mammalian striated muscles postnatally. The porcine TR Æ 1, TR Æ 2 and TR (cid:226) 1 cDNAs were ﬁrst cloned, sequenced and characterised by Northern blotting. A quantitative analysis of TR isoform expression was then undertaken, using RNase protection analysis with novel riboprobes designed to detect relative expression levels of TR Æ 1, TR Æ 2, TR (cid:226) 1 and TR (cid:226) 2, in functionally distinct muscles from 7-week-old pigs kept under controlled conditions of nutrition and thermal environment. We found a striking muscle-speciﬁc pattern of TR Æ isoform distribution: in heart the mRNA level of TR Æ 2 (non-TH binding) was markedly greater ( P <0·01) than that of TR Æ 1 (TH binding); in longissimus dorsi the opposite pattern of expression occurred (TR Æ 1>TR Æ 2, P <0·001); in soleus , diaphragm and rhomboideus there were no di V erences between the two isoforms. The overall abundance of TR (cid:226) was very much lower than that of TR Æ , and TR (cid:226) 1 was expressed at a higher level than TR (cid:226) 2 in all muscles. Together with recent data from TR gene inactivation studies and the established role of TH in determining myosin heavy chain isoform expression and muscle phenotype, these results suggest a role for di V eren-tial expression of TR isoforms in acquisition and maintenance of optimal cardiac and skeletal muscle function.
Monitoring Annoyance and Stress Effects of Wind Monitoring Annoyance and Stress Effects of Wind Turbines on Nearby Residents: A Comparison of U.S. Turbines on Nearby Residents: A Comparison of U.S. and European Samples and European Samples

As wind turbines and the number of wind projects scale throughout the world, a growing number of individuals might be affected by these structures. For some people, wind turbine sounds and their effects on the landscape can be annoying and could even prompt stress reactions. This comparative study analyzed a combined sample of survey respondents from the U.S., Germany and Switzerland. It utilized a newly developed assessment scale (AS-Scale) to reliably characterize these stress-impacted individuals living within populations near turbines. Findings indicate low prevalence of annoyance, stress symptoms and coping strategies. Noise annoyance stress (NAS-Scale) was negatively correlated with the perceptions of a lack of fairness of the wind project's planning and development process, among other subjective variables. Objective indicators, such as the distance from the nearest turbine and sound pressure level modeled for each respondent, were not found to be correlated to noise annoyance. Similar result patterns were found across the European and U.S. samples.
Decreased T Cell Levels in Critically Ill Coronavirus Patients: single-center, prospective and observational study

Background: Since Dec. 2019, COVID-19 pandemic has been outbreak. T cells play an important role in dealing with various disease-causing pathogens. However, the role of T cells played in COVID-19 patients is still unknown. Our study aimed to describe immunologic state of the critical ill COVID-19 patients. Methods: 63 patients with confirmed COVID-19 pneumonia admitted Department of Intensive Care Unit of the First Affiliated Hospital of Harbin Medical University. The immunologic characteristics（lymphocyte apoptosis, the expression of PD-1 and HLA-DR in T cells, T cell subset levels, redistribution and the production of inflammatory factors）as well as their laboratory parameters were compared between severe group and critical group.Results: The level of T cells in peripheral blood was decreased in critical patients compared with that in severe patients, but the expression levels of PD-1 (CD4+: 24.71% VS 30.56%; CD8+: 33.05% VS 32.38%) and HLA-DR (T cells: 36.28% VS 27.44%; monocytes: 20.58% VS 23.83%) in T cells were not significantly changed, and apoptosis and necrosis were not different in lymphocytes (apoptosis: 1.04% VS 1.27%; necrosis: 0.67% VS 1.11%), granulocytes, or monocytes between those two groups.Conclusions: There is severe immunosuppression in critical ill COVID-19 patients. Redistribution of T cells might be the main reason for lymphocytic decline. Decreasing the infiltration of T lymphocytes in the lung may be beneficial for the treatment of COVID-19. Trial registration: The study was approved by the Ethics Committee of the First Affiliated Hospital of Harbin Medical University. Code number: kyk2020003.
The Chronology of Occupation on Maungarei {Mount Wellington): a Large Volcanic Cone Pa in Auckland

Maungarei is one of a number of very extensive pre-European Maori settlements on the volcanic cones of Auckland. It was tbe scene of several major rescue excavations between 1960 and 1972. Recently obtained radiocarbon dates suggest that allbougb occupation may have begun earlier, the main phase of terrace construction and pit building on the cone was between the mid-sixteenth and late seventeenth centuries A.D. There was some later occupation of tbe substantially remodelled crater rim in the eighteenth or early nineteenth centuries, although the site was apparently uninhabited when Europeans first visited the area.