Miracle-dz/UniFAR-FTUs huggingface dataset:
Teacher-student -task -interactions in a motor skills programme for an adolescent boy with autism spectrum disorder: a systematic observation study (Interacción profesor-alumno-tarea en un programa de desarrollo de capacidades motrices en un adolescente con TEA: un estudio de observación sistemática

Abstract This study illustrates the potential offered by observational methodology for analysing spontaneous behaviours and interactions by students with autism spectrum disorder (ASD). We present a case study in which we observed, analysed and interpreted how an adolescent boy with ASD interacted both verbally and non-verbally with his physical education teacher and with different gym- and pool-based tasks within a motor skills development programme. The data were annotated in the free software LINCE using an ad hoc observation instrument combining a field format and category systems. The quality of the data was confirmed by high levels of interobserver agreement (calculated quantitatively using Cohen’s kappa statistic). Two diachronic techniques at the forefront of observational methodology, lag sequential analysis (GSEQ) and polar coordinate analysis (HOISAN), were used to investigate activating and inhibitory relationships corresponding to desirable and undesirable verbal and non-verbal interactions between the boy and the different zones in the motor skills circuits and the teacher’s responses to these interactions.
Tumor Necrosis Factor and its Soluble Receptors as Potential Diagnostic Markers of Endometriosis

Introduction Tumor necrosis factor (TNF) is a proinflammatory and angiogenic factor produced by activated macrophages. TNF acts through the cell membrane receptors TNFR1 and TNFR2, whose soluble forms play an important role in regulating TNF activity through competition with its receptors. The aim of this study was to evaluate whether TNF and/or its soluble receptors are useful to detect endometriosis in women undergoing laparoscopy for gynecological complains. Methods This was a prospective, controlled, cross-sectional study including 75 consecutive women scheduled for gynecological laparoscopy due to chronic pelvic pain, infertility, or a pelvic image suggestive of endometrioma. Plasma TNF and soluble TNF receptors (sTNFR1 and sTNFR2) were measured by flow cytometry with the Cytometric Bead Array Human TH1/TH2 Kit (BD Biosciences). Results Women ultimately proven to have endometriosis had lower preoperative plasma levels of sTNFR1 (median 81 pg/mL vs. 121 pg/mL, p<0.05), resulting in higher TNF/sTNFR1 ratios compared to those without endometriosis (0.055 vs. 0.033, p<0.05). Using the cut-off <108 pg/mL for plasma sTNFR1 to detect endometriosis in this setting, the sensitivity was 51.6% (95% confidence interval [CI], 35%-68%), the specificity was 75.0% (95% CI, 61%-85%) and the positive likelihood ratio was 2.1 (95% CI, 1.1-3.8). The area under the ROC curve was 0.647 (SE = 0.065; 95% CI, 0.519-0.774; p = 0.031). Conclusions Plasma sTNFR1 levels are lower in symptomatic women with confirmed endometriosis compared to symptomatic women without endometriosis. The lower plasma sTNFR1 levels may increase the bioavailability of TNF, thereby contributing to the systemic low grade inflammation associated with endometriosis.
HEAT SHOCK PROTEIN GP96 DRIVES DICHOTOMOUS LYMPHOCYTE RESPONSES VIA DNA METHYLOME REMODELING AND STAT1 SIGNALING IN ANTIGEN PRESENTING CELLS

Immune responses primed by endogenous heat shock proteins (HSPs), specifically gp96, have been used for immunotherapy of cancer. Immunization with low doses of gp96 primes a response that is dominated by T helper type 1 (Th1) cells and cytotoxic T lymphocytes (CTLs), which allows for recognition and killing of tumor cells. However, increasing the dose of gp96 primes a response characterized by regulatory T (Treg) cells and immunosuppression. Although the T cell responses driving this dose dichotomy have been studied in multiple systems, innate mechanisms that control T cells in the context of gp96 immunization remains unknown. The antigen presenting cells (APCs) involved in this response are the main focus of Chapters 1 and 2 of this thesis. Here we show gp96 preferentially engages conventional and plasmacytoid dendritic cells (pDCs) under low and high doses respectively, through the HSP receptor CD91. We show that DNA methyltransferase 1 (DNMT1) is active in multiple APC population in response to gp96 stimulation, and that global DNA methylome and protein expression changes occur in these populations in response to in vivo immunization. Methylation-dependent upregulation of neuropilin-1 (Nrp1) on pDCs enables long term interactions with Treg cells that enhance their function in suppressing ongoing Th1 anti-tumor immunity. Our study defines a CD91-dependent mechanism through which gp96 controls dichotomous immune responses, relevant to the therapy of cancer and autoimmunity. Additionally, we are interested in the signaling pathways initiated by gp96-CD91 interaction. Previous studies have shown that NF-B and p38 MAPK are activated in HSP-responsive macrophages, but the consequences of p38 activation were not investigated. Chapter 3 will focus on the downstream mediators of p38, specifically the transcription factor STAT1, and the cytokine expression and secretion that follows. We show that gp96-treated macrophages upregulate STAT1-dependent cytokines as a result of STAT1 phosphorylation. This event requires intact CD91 and p38 MAPK. Importantly, STAT1 target CXCL10 is upregulated in response to gp96 and is critical for APC-NK cell crosstalk. Given that NK cells are required for anti-tumor immunity elicited by gp96 immunization, we hypothesize that STAT1 activation in responding APCs is necessary for tumor rejection.
Human Resource Development and Spiritual Intelligence: An investigation amongst Management students in Delhi NCR

: The study seeks to investigate the relationship between spiritual intelligence and its relative impact on students’ academic performance. Several studies link SI with intellectual development. This study aims to analyse the phenomenon of spiritual intelligence (SI) within the framework of human resource development (HRD) research. Qualitative and quantitative data were analysed. The study was conducted among management students residing in Delhi NCR. The findings confirm that spiritual quotient factors are applicable in the Indian context. In addition, the study reveals that the spiritual quotient is significantly correlated with academic performance. The study uses the scale developed by King (2008) to measure spiritual intelligence through spiritual intelligence self report inventory (SISRI) which includes 24 statements. From
GATTACA: Lightweight Metagenomic Binning with Compact Indexing of Kmer Counts and MinHash-based Panel Selection

We introduce GATTACA, a framework for rapid and accurate binning of metagenomic contigs from a single or multiple metagenomic samples into clusters associated with individual species. The clusters are computed using co-abundance profiles within a set of reference metagnomes; unlike previous methods, GATTACA estimates these profiles from k-mer counts stored in a highly compact index. On multiple synthetic and real benchmark datasets, GATTACA produces clusters that correspond to distinct bacterial species with an accuracy that matches earlier methods, while being up to 20× faster when the reference panel index can be computed offline and 6× faster for online co-abundance estimation. Leveraging the MinHash technique to quickly compare metagenomic samples, GATTACA also provides an efficient way to identify publicly-available metagenomic data that can be incorporated into the set of reference metagenomes to further improve binning accuracy. Thus, enabling easy indexing and reuse of publicly-available metagenomic datasets, GATTACA makes accurate metagenomic analyses accessible to a much wider range of researchers.
Leader Unethical Pro-Organizational Behavior and Employee Unethical Conduct: Social Learning of Moral Disengagement as a Behavioral Principle

Unethical behavior in organizations has attracted much attention among researchers, yet we know little about when and why unethical behavior conducted by leaders that is intended to benefit the organization—or leader unethical pro-organizational behavior (UPB)—might translate into employee unethical behavior. Drawing on a social-learning-of-principle perspective, which proposes that people can learn the principles that govern observed behaviors, we propose that employees, especially those with a high power distance orientation, can abstract and learn a moral disengagement behavioral principle by observing leader UPB. This learned moral disengagement behavioral principle then enables them to engage in unethical behaviors that may be intended to benefit or harm their organizations. In two multiwave field studies with data collected from real estate agents, we found overall support for our theoretical model but the moderating effect of power distance orientation. We discuss some key theoretical and practical implications of these findings.
Wilt incidence and cultural variability of Fusarium oxysporum f.sp. udum collected from different districts of Uttar Pradesh

Pigeonpea (Cajanus cajan) L. Millsp. is an important legume crop widely used as food grain as it is rich source of protein, carbohydrate, essential amino acids, minerals and fibres. India is reknowned as a major pigeonpea producer country all over the world. Pigeonpea is susceptible to a number of pathogens, among which Fusarium oxysporum f.sp. udum is considered as the most important fungal pathogen causing considerable economic loss in India and all over the world. Among different states in India, Uttar Pradesh is the major pigeonpea growing state having most of the wilt susceptible pigeonpea growing areas causing considerable yield losses. In the present study, collection of diseased samples from wilt affected areas of different districts, isolation of test fungi, test of pathogenicity in pots under wirenet house condition was conducted. Further test of wilt incidence of the selected strains of Fusarum oxysporum f.sp. udum through root dip method and soil inoculation method was undertaken in earthen pots under wirenet house to make a precise comparison between the two methods. Cultural variabilities like radial growth, growth rate and mycelia dry weight among the selected isolates were studied under laboratory conditions.
Chromosome numbers of Carex

Chromosome numbers were determined for 97 samples of 95 sedge taxa (Carex) from the following countries: Austria (6 records), Bulgaria (1), the Canary Islands (Spain, 1), Cape Verde (1), the Czech Republic (51), Hungary (1), Italy (2), Norway (8), Russia (15), Slovakia (1), Sweden (1) and 9 North American plants cultivated in Czech botanical gardens. Chromosome numbers for Carex argunensis, C. callitrichos, C. campylorhina, C. flavocuspis subsp. krascheninnikovii, C. paniculata subsp. hansenii, C. pallida, C. quadriflora and C. xiphium are reported here for the first time. The first reports are presented for the European portion of the distribution area of Carex obtusata and for the Central European portion of the distributional areas of C. chordorrhiza, C. otrubae, C. rhizina and C. strigosa.
In vitro antibacterial effect of Argentine propolis extracts on Streptococcus mutans and Actinomyces viscosus

Aim: In the present study, the antibacterial activity of the Ethanol Extract of Propolis (EEP), collected from various regions (Mendoza, Santiago del Estero, and Corrientes) in Argentina, against Streptococcus mutans ATCC® 35668™ and Actinomyces viscosus ATCC® 15987™ (MicroBioLogics Inc., USA) was investigated. Methods: Identification of geographic and botanical origin was based on a reconnaissance survey. Phytochemical screening of propolis was carried out on ethanolic extracts using standard methods to identify the constituents (aluminum chloride colorimetric method, Folin-Ciocalteu colorimetric method, thin layer chromatography). The agar diffusion method (discs and wells) and serial dilution method (plates and tubes) were used to evaluate the antibacterial activity of EEP. Results: EEP exerted various degrees of antibacterial activity against S. mutans and A. viscosus, depending on the geographic area of collection. Phytochemical screening showed that the bioactive compounds correspond to phenolic compounds and flavones. EEP from Tunuyán (Mendoza), where the most abundant vegetation belongs to Populus sp. , showed the highest content of phenolic compounds (220.92±2.01 mg/g) and flavonoids (30.39±0.25 mg/g). This sample showed the most profound antibacterial activity among the EEP tested. By the agar-well diffusion method, we found a high susceptibility with an inhibitory halo of 11.25 ± 4.68 mm and 10.90 ± 4.21 mm against S. mutans and A. viscosus, respectively. It also presented low Minimum Inhibitory Concentration and Minimum Bactericidal Concentration values against S. mutans (MIC 0.05 mg/mL - MBC 0.46 mg/mL) followed by A. viscosus (MIC 0.11 mg/mL - MBC 0.93 mg/mL). Conclusions: The combined results from all methods indicated that S. mutans is more susceptible to the effect of the Tunuyán EEP than A. viscosus.Uniterms: Propolis. Streptococcus mutans. Actinomyces viscosus. Microbial sensitivity tests.
Distribution and abundance of Panulirus spp. phyllosomas off the Mexican Caribbean coast

We evaluated the abundance and distribution of Panulirus spp. phyllosomas collected during two oceanographic cruises in March 2006 and January 2007 along the Mexican Caribbean coast. In total, 1138 phyllosomas were collected in 2006, and 492 were collected in 2007, comprising three families: Palinuridae; Scyllaridae; and Sinaxidae. The most abundant species of Panulirus for both cruises was Panulirus argus (Latreille, 1804). DNA barcoding methods also confirmed the identity of the phyllosomal stages of Panulirus guttatus (Latreille, 1804). The most abundant phyllosomal stages of P. argus in both years were early (I–III) and mid stages (IV–VIII) mostly found near Banco Chinchorro. The least abundant late stages (IX–X) were widely dispersed offshore. During both cruises, >70% of phyllosomal abundance was concentrated in the surface layers (0–50 m). Statistical models indicated that depth, along with year, geographical area, and time of day, were important for early- and mid-stage phyllosoma stages. The distribution and densities of phyllosomas off Quintana Roo differed among years and areas, likely due to varying environmental conditions and mediated by physical processes and the seasonality of reproductive activity of the local and regional spawning stock. In addition, early-stage phyllosomas appeared to avoid surface waters during periods of increased moonlight.
Contributions of assessment-related critical incidents to language teacher identity development

ABSTRACT While research on teachers’ Critical Incidents (CIs) has grown exponentially, little research has been done on teachers’ assessment-related CIs, much less examining the contributions of such CIs to their identity sense-making. This study aimed to fill some of this gap by exploring assessment-related CIs of 13 Iranian L2 teachers and the associated contributions to their identity development. Data were collected from narrative frames and cognitive interviews and analyzed via grounded theory and thematic analysis. The results indicated that the teachers narrated more teaching low incidents than teaching high incidents. The CIs had influenced the teachers’ self-images, had mediated the way they defined their role in relation to other institutional participants, and were accompanied by institutional restrictions that had limited the teachers in enacting their preferred assessment practices and developing their autonomy. Results of the study offer implications to policy-makers and teacher educators regarding the importance of unpacking teachers’ assessment CIs to enhance the effectiveness of their educational systems.
Avifauna of Saurashtra University Campus, Rajkot, Gujarat, India

We examined the avifauna of Saurashtra University Campus (SUC), Rajkot, Gujarat from July to December 2017. The study area was divided into four sections: North (N), East (E), South (S) and West (W) and surveyed over 18 visits (four line transects/visit). We recorded a total of 82 bird species from 67 genera, 40 families and 16 orders. Of these 57 species were terrestrial and 25 aquatic. By population size the most abundant birds were members of Columbidae (28%), Sturnidae (13%), and Charadridae (8%). Seventy per cent of birds observed (n=7665) were classed as very common and 2% (n=261) as very rare. Species density (S/N = 3.39) and population density (n/N = 196) were at their maximum in December. Ecological indices on temporal base reveal high species richness and Simpson diversity (1/D =17.0 and 1-D= 0.942) in August and November and Shannon diversity was high (H’=3.275) in November during study period.
Influence of rainfall on population dynamics and survival of a threatened rodent (Pseudomys novaehollandiae) under a drying climate in coastal woodlands of south-eastern Australia

Abstract. In Mediterranean systems, such as south-east Australia, predictions of climate change including lower rainfall and extended drought, threaten vulnerable mammal species. We investigated the relationship between rainfall and population dynamics for a native rodent at risk of extinction, the New Holland mouse (Pseudomys novaehollandiae). In the eastern Otways, the species was significantly influenced by rainfall, exhibiting a population irruption (15–20 individuals ha–1) following six years of above-average rainfall and a precipitous decline to site extinction during subsequent drought. The decline was predominantly related to loss of adults before and during breeding seasons, together with an apparent decrease in juvenile survival. Population abundance was positively correlated with a rainfall lag of 0–9 months. We propose that the response of this omnivore to high rainfall was mediated through increased productivity and that rainfall decline resulted in resource depletion and population decline. Under a drying climate the direct impacts of rainfall decline will continue. However management of other threats may increase the species’ resilience. Burning to provide optimal successional vegetation, protection of refugia, and predator control are priorities. However, burning should be avoided during drought, as the likelihood of local extinctions is substantial.
Márkus and the retrieval of the sociological Adorno

Major sociological work related to the culture industry thesis was undertaken by Adorno during his period as a ‘refugee scholar’ in the USA. It has been charged with a ‘sociological deficit’ by leading figures within critical theory, typically without reference to that US context. A dialogue with Márkus’s work on Adorno and the Marxian production paradigm can redress failings in those critiques. However, such a task is complicated by the limitations of Márkus’s own major essay on this topic. This paper thus conducts an immanent critique of Márkus: ‘Márkus against Márkus’. Márkus’s proposals for the application of the Marxian production paradigm to aesthetic culture and his prospective vision for critical theory are so found to be very compatible with Adorno’s related work.
Effects of accelerated ageing and cryopreservation on seeds and embryonic axes of Phaseolus vulgaris L and Arachis hypogaea L. Germination and seedlings vigor

The effects of artificial aging and cryopreservation methods on the germination of seeds and embryonic axes of Phaseolus vulgaris and Arachis hypogaea , were studied. Aging and cryopreservation treatments in bean seeds not affect the germination percentage, reaching values not significantly different from control. Germination percentage was higher when isolated embryonic axes were studied. Aging treatments gave rise to larger bean seedlings than the controls and cryopreservation treatments affected the size depending on the explant used. In groundnut seeds, aging treatments and cryopreservation positively affected germination and vigor of seedlings, but embryonic axes from not rehydrated aging seeds not germinate. Undried groundnut seeds not survive cryopreservation, while the dried ones showed a germination behavior superior to the control. Embryonic axes tolerate immersion in liquid nitrogen but when droplet-vitrification was used, formed callus instead of seedlings. Electrolyte leakage was always higher in embryonic axes than in seeds, both in beans and groundnut, and not to have a significant effect, under the conditions studied, on germination and vigor of seedlings. The present study evidences the possibility of cryopreserving, by simple procedures, germplasm of beans and groundnut, and to verify the aging tolerance of the seeds and embryonic axes of these important species.
Using GRU based deep neural network for intrusion detection in software-defined networks

This paper considers the possibility of using machine learning methods in solving the problem of intrusion detection in software-defined networks (SDN). The work is devoted to the research and development of a network attack classifier, which is a core of the intrusion detection systems. To evaluate the methods, an existing data set was used, which includes network traffic records with a several different network attack scenarios. A comparison of machine learning methods implementing neural networks on a selected data set is presented. Based on the results, it can be concluded that the task of intrusion detection in software-defined networks can be successfully solved using deep neural networks.
It’s a Peoples Game, Isn’t It?! A Comparison Between the Investment Returns of Business Angels and Machine Learning Algorithms

Investors increasingly use machine learning (ML) algorithms to support their early stage investment decisions. However, it remains unclear if algorithms can make better investment decisions and if so, why. Building on behavioral decision theory, our study compares the investment returns of an algorithm with those of 255 business angels (BAs) investing via an angel investment platform. We explore the influence of human biases and experience on BAs’ returns and find that investors only outperformed the algorithm when they had extensive investment experience and managed to suppress their cognitive biases. These results offer novel insights into the role of cognitive limitations, experience, and the use of algorithms in early stage investing.