Miracle-dz/UniFAR-FTUs huggingface dataset:
A 20-Gb/s/Pin Compact Single-Ended DCC-Less DECS Transceiver With CDR-Less RX Front-End for On-Chip Links

This article presents a 20-Gb/s/pin 0.0024-mm2 single-ended data-embedded clock signaling (DECS) transceiver (TRX) for short-reach on-chip links. The receiver (RX) directly recovers (self-slicing) and deserializes (auto-deserialization) the data from the DECS input of the RX front-end without a clock and data recovery (CDR) or clock and data alignment (CDA) circuits, while improving the timing requirement and the tolerance to duty cycle error and supply noise. At 20 Gb/s/pin, the horizontal eye was measured 0.99 UI at nominal and remained equal to or larger than 0.88 UI either when the clock duty cycle changed from 40% to 60% or when a 50-MHz 300-mV<inline-formula> <tex-math notation="LaTeX">$_{\mathrm {p-p}}$ </tex-math></inline-formula> sinusoidal supply noise was injected to the RX from a printed circuit board (PCB). In addition, the proposed RX could tolerate a 200-MHz 300-mV<inline-formula> <tex-math notation="LaTeX">$_{\mathrm {p-p}}$ </tex-math></inline-formula> sinusoidal supply noise and 200-mV<inline-formula> <tex-math notation="LaTeX">$_{\mathrm {p-p}}$ </tex-math></inline-formula> crest factor 7 (CF7) Gaussian supply noise, while achieving 0.90 UI horizontal eye size in both cases. Because complex clocking circuits were removed, the active RX core excluding on-die-terminations (ODTs) achieved the smallest area occupancy of 0.000058 mm2 and decent energy efficiency of 0.18 pJ/b. With the proposed technique, a compact high-speed short-reach on-chip link is feasible without expensive high-speed duty cycle correction (DCC), duty cycle detection (DCD), CDR, or CDA. The proposed TRX was fabricated in 28-nm CMOS low-power performance (LPP) technology.
Quantitative, Targeted Analysis of Gut Microbiota Derived Metabolites Provides Novel Biomarkers of Early Diabetic Kidney Disease in Type 2 Diabetes Mellitus Patients

Diabetic kidney disease (DKD) is one of the most debilitating complications of type 2 diabetes mellitus (T2DM), as it progresses silently to end-stage renal disease (ESRD). The discovery of novel biomarkers of early DKD becomes acute, as its incidence is reaching catastrophic proportions. Our study aimed to quantify previously identified metabolites from serum and urine through untargeted ultra-high-performance liquid chromatography coupled with electrospray ionization-quadrupole-time of flight-mass spectrometry (UHPLC-QTOF-ESI+-MS) techniques, such as the following: arginine, dimethylarginine, hippuric acid, indoxyl sulfate, p-cresyl sulfate, L-acetylcarnitine, butenoylcarnitine and sorbitol. The study concept was based on the targeted analysis of selected metabolites, using the serum and urine of 20 healthy subjects and 90 T2DM patients with DKD in different stages (normoalbuminuria—uACR < 30 mg/g; microalbuminuria—uACR 30–300 mg/g; macroalbuminuria—uACR > 300 mg/g). The quantitative evaluation of metabolites was performed with pure standards, followed by the validation methods such as the limit of detection (LOD) and the limit of quantification (LOQ). The following metabolites from this study resulted as possible biomarkers of early DKD: in serum—arginine, dimethylarginine, hippuric acid, indoxyl sulfate, butenoylcarnitine and sorbitol and in urine—p-cresyl sulfate.
Predicting Chemical Composition and Apparent Total Tract Digestibility on Freeze-Dried Not Ground Faeces Using Near-Infrared Spectroscopy in Pigs

Simple Summary Near-infrared reflectance spectroscopy (NIRS) is widely used to predict the nutritional value of raw materials and complete feeds in feed mills. Recently, faecal NIRS was proposed as a fast and cheap method to predict nutrient digestibility to partially replace in vivo digestibility trials. Previous studies used freeze-dried ground (FDG) faeces via NIRS, but the use of not ground (FDNG) faeces could save time and workload. The objective of the present study was to compare the results obtained with NIRS using faecal samples in two forms, FDNG and FDG, to predict faecal chemical composition and apparent total tract digestibility (ATTD) coefficients. Faecal samples were collected from grower-finisher pigs at pen level, freeze-dried, and analysed via NIRS as FDNG and FDG faeces. NIRS calibrations were developed and successfully predicted faecal chemical components and ATTD coefficients of nutrients for both FDNG and FDG faeces. Thus, faecal NIRS is a potential tool to evaluate faeces’ chemical components and ATTD coefficients of nutrients, and those are successfully predicted using FDNG faeces, saving analysis time and workload. Abstract The present study aimed to compare NIRS results using freeze-dried ground or not ground (FDG or FDNG) faeces to predict faecal chemical composition and apparent total tract digestibility (ATTD) coefficients. Two different batches of pigs were used (n = 20 mixed sex pens/batch; 11 pigs/pen; Duroc × (Large White × Landrace)). The first batch of pigs (B1; 50.1 ± 3.44 kg body weight (BW)) was used at 13 wks of age and the second batch (B2; 87.0 ± 4.10 kg BW) was used at 18 wks of age. For both B1 and B2, pens were assigned to five diets formulated to obtain a control [10.03 MJ of net energy (NE), 160.0 g of crude protein (CP), and 9.5 g of standardized ileal digestive (SID) lysine (Lys) per kg of feed], low protein (132.0 g CP and 7.5 g SID Lys), high protein (188.0 g CP and 11.5 g SID Lys), low energy (9.61 MJ NE/kg), and high energy (10.45 MJ NE/kg) diets. After a 10-day adaptation period, one faecal sample was collected daily from each pen floor during 6 days in both B1 and B2 (n = 120/batch). Faecal samples were freeze-dried and analysed via NIRS as FDNG and FDG faeces. Dry matter (DM), organic matter (OM), CP, gross energy (GE), fat, and ATTD coefficients were analysed/calculated. The NIRS calibrations were evaluated by cross-validation, splitting the data in four random groups, or using the leave-one-out method. For both FDNG and FDG faeces, coefficients of determination for calibration (R2cv) and residual predictive deviation (RPD) values were: close to 0.9 and 3 for DM and CP, 0.7–0.8 and ≥2 for OM and GE, 0.6 and <2 for fat, and 0.54–0.75 and ≤2 for ATTD coefficients, respectively. CP was better predicted using FDG faeces (p < 0.05), while DM and OM ATTD were better predicted using FDNG faeces (p < 0.05). In conclusion, NIRS successfully predicts faeces’ chemical components and ATTD coefficients of nutrients using FDNG or FDG faeces.
Environmental Influences on the Intensity and Configuration of Tropical Cyclone Concentric Eyewalls in the Western North Pacific

Using brightness temperature data from passive microwave satellite imagery, this study examines tropical cyclones (TCs) with concentric eyewall (CE) in the western North Pacific between 1997 and 2011. The identified CEs are divided into two types according to the characteristics of the eyewall replacement cycle (ERC) in the microwave imagery: a CE with a typical ERC (T-ERC) and a CE without an ERC (N-ERC). It is indicated that 88 % T-ERCs reach peak intensity near (0.2 h after on average) CE formation, whereas 90 % N-ERCs reach peak intensity prior to (22.0 h on average) CE formation. In general, N-ERCs tend to occur when there are strong interactions between the environment and the CE, whereas T-ERCs occur in a relatively quiet environment. The three-dimensional conceptual models of the environmental configurations for both CE types are proposed. Specifically, N-ERCs are accompanied by stronger southwesterly and southeasterly inflows, active low-level trough, and stronger subtropical high (SH) and South Asia high (SAH), compared with T-ERCs. For N-ERCs, the stronger inflows may bring in a large amount of moisture, and the active low-level trough may result in a large vertical wind shear (VWS). The stronger SH and SAH may contribute to changes in the intensity and direction of the VWS for N-ERCs, and hence trigger the development of local convection in the outer eyewall. The asymmetries in the convection of the outer eyewall may weaken the ability to cut off the radial inflow to the inner eyewall. Consequently, N-ERCs fail to finish the ERC and weaken rapidly in intensity, even though the moisture remains sufficient after CE formation.
Effects of Different Eimeria Inoculation Doses on Growth Performance, Daily Feed Intake, Gut Health, Gut Microbiota, Foot Pad Dermatitis, and Eimeria Gene Expression in Broilers Raised in Floor Pens for 35 Days

Simple Summary Coccidiosis, which is induced by Eimeria spp. , is one of the most predominant diseases and causes tremendous economic losses in the world. The effects of Eimeria infection on broilers at slaughter ages in floor pen conditions should be elucidated to conduct further studies investigating the effects of feed additives and bioactive compounds as alternatives for anti-coccidial drugs in broilers. The study was aimed to investigate the effects of different inoculation doses of E. acervulina, E. maxima, and E. tenella with different doses on growth performance, gut ecosystem, and oocyst shedding in broilers raised in floor pens for 35 days. Eimeria infection decreased body weight (BW) in the acute phase (D 21), and this effect was prolonged to the final day (D 35). Eimeria oocysts were observed in the litter until D 35, which may indicate that Eimeria spp. reinfected broilers. Eimeria infection dramatically reduced crude fat (CF) digestibility in the acute phase, which may be associated with reduced fat content in the broilers on D 35. Gut microbiota was negatively affected by Eimeria infection in both acute phase and on D 35. In conclusion, Eimeria infection negatively affected the growth performance and gut ecosystem in broilers, and the negative effects were prolonged to D 35 in floor pen conditions. Abstract The study was conducted to investigate the effects of different Eimeria inoculation doses on the growth performance, gut ecosystem, and body composition of broilers in floor pens for 35 days. A total of 750 15-day-old broilers were allocated to five experimental groups with six replicate pens. The five experimental groups included unchallenged control (CON); Eimeria dose 1 (ED1): E. acervulina: 31,250/E. maxima: 6250/E. tenella: 6250; Eimeria dose 2 (ED2): E. acervulina: 62,500/E. maxima: 12,500/E. tenella: 12,500; Eimeria dose 3 (ED3): E. acervulina: 125,000/E. maxima: 25,000/E. tenella: 25,000; and Eimeria dose 4 (ED4): E. acervulina: 250,000/E. maxima: 50,000/E. tenella: 50,000. On D 21, BW were linearly reduced by increased Eimeria inoculation doses (p < 0.01). On D 35, the Eimeria challenge groups had significantly lower BW compared to the CON group. Increased Eimeria inoculation doses linearly decreased crude fat (CF) (p < 0.01) on D 21. Increased Eimeria inoculation doses tended to increase the relative abundance of the phylum Proteobacteria (p = 0.098) on D 21. On D 35, lean:fat was linearly reduced by increased Eimeria inoculation doses (p < 0.05). Eimeria infection negatively influenced growth performance and gut health in broilers in the acute phase, and the negative effects were prolonged to D 35 in floor pen conditions.
Atypical Presentation of Primary Hyperparathyroidism as Recurrent Pancreatitis: A Case Report With a Review of the Literature

The majority of the patients with primary hyperparathyroidism (PHPT) are asymptomatic. The most common organ systems involved in PHPT are the kidneys and the skeletal system. In rare instances, acute or chronic pancreatitis may be presenting feature in PHPT patients. The association between these both diseases is still the topic of debate. Here, we put forth a case of a 52-year-old female with three episodes of pancreatitis in the last six months who was diagnosed with PHPT during the fourth episode of pancreatitis based on raised serum amylase and serum lipase levels along with ultrasonography (USG) findings of the abdomen. Pancreatitis in the absence of additional risk factors such as gallstones and alcohol abuse along with raised parathyroid hormone (PTH), hypercalcemia and osteolytic bone lesions led us towards the diagnosis of PHPT. On radio imaging such as MRI and CT scans of the neck, parathyroid adenoma was found in the posterior aspect of the right lobe of the thyroid. She was treated with parathyroidectomy. Serum calcium and PTH levels normalised postoperatively. As can be seen from our case, recurrent pancreatitis with hypercalcaemia should be evaluated for PHPT.
A Generic Sure Independence Screening Procedure

ABSTRACT Extracting important features from ultra-high dimensional data is one of the primary tasks in statistical learning, information theory, precision medicine, and biological discovery. Many of the sure independent screening methods developed to meet these needs are suitable for special models under some assumptions. With the availability of more data types and possible models, a model-free generic screening procedure with fewer and less restrictive assumptions is desirable. In this article, we propose a generic nonparametric sure independence screening procedure, called BCor-SIS, on the basis of a recently developed universal dependence measure: Ball correlation. We show that the proposed procedure has strong screening consistency even when the dimensionality is an exponential order of the sample size without imposing sub-exponential moment assumptions on the data. We investigate the flexibility of this procedure by considering three commonly encountered challenging settings in biological discovery or precision medicine: iterative BCor-SIS, interaction pursuit, and survival outcomes. We use simulation studies and real data analyses to illustrate the versatility and practicability of our BCor-SIS method. Supplementary materials for this article are available online.
Maternal cognitive mind-mindedness and maternal time as predictors of inhibitory control in toddlerhood

ABSTRACT This study examined how maternal cognitive mind-mindedness, maternal time, and their interactions predict inhibitory control in Chinese children. Participants were 88 toddlers (59% girls) and their mothers from Beijing, China. Maternal cognitive mind-mindedness was coded in mother–child interactions and mothers reported weekly interaction duration at 14, 25, and 38 months of children's ages. Children's inhibitory control and language were assessed by age-appropriate standard assessments at 25 and 38 months. Regression analyzes showed that the interactions of cognitive mind-mindedness with maternal time were positively associated with inhibitory control both concurrently and longitudinally, after accounting for children's language and gender. Specifically, for mothers who spent more time with her child, cognitive mind-mindedness positively predicted inhibitory control, whereas for mothers who spent less time with her child, this prediction was non-significant. These findings suggest that spending substantial ‘quality time’ with children is key to facilitating inhibitory control skills in early childhood.
Global well-posedness for $n$-dimensional Boussinesq system with viscosity depending on temperature

In this paper, we study the global well-posedness issue for the Boussinesq system with the temperature-dependent viscosity in R n ( n ≥ 2). With a temperature damping term, we ﬁrst get a global solution in R 2 , provided the initial temperature is exponentially small compared with the initial velocity ﬁeld. Then, using a weighted Chemin-Lerner-type norm, we can also give a global large solution in R n if the initial data satisﬁes a nonlinear smallness condition. In particular, our results imply the global large solutions without any smallness conditions imposed on the initial velocity.
Reproductive potential of the blue crab spawning stock in Chesapeake Bay across eras and exploitation rates using nemertean worms as biomarkers

: Assessments of reproductive potential and spawning history of marine and estuarine crabs are limited due to issues with determination of age and spawning history. The spawning stock of the blue crab Callinectes sapidus in Chesapeake Bay was heavily fished and declined in the 1990s. Management actions were implemented between 2001 and 2008 to reduce spawning stock exploitation and trigger recovery. Whether these actions impacted the demography of female spawners is unknown. We assessed demographics of overwintering mature female crabs in 1992−1996 and 2020−2022 by classifying them as first-year (imminent primiparous) or second-year (primiparous and multiparous) spawners based on presence of mature nemertean worms (Carcinonemertes carcinophila) in their gill chambers. We also investigated organismal and environmental predictors of second-year spawners. We provide the first annual estimates of the proportion of multi-year spawners at the population level. Management actions reduced exploitation rates by 41% after 2008, and the proportion of second-year spawners was greater than in the 1990s. Nonetheless, exploitation rate in a given year did not predict proportion of second-year spawners in the following year. Second-year spawners tended to be smaller females, or females with a high gonadosomatic index or longevity indicators (i.e. fouling by barnacles). High proportions of large, highly fecund, overwintering first-year spawners in the 2020s support the need for enhanced protection of females in spring to allow these females to spawn. Finally, nemertean worms are a useful, easily implemented tool to determine spawning history and age-specific reproductive potential of crabs that undergo a terminal molt prior to spawning.
Do Industry Specialist Audit Firms Inﬂuence Real Earnings Management? The Role of Auditor Independence

economically important auditee. Our ﬁndings remain robust after controlling for endogeneity and self-selection bias and performing several further analyses. This study is the ﬁrst to prove that auditor independence can moderate the effectiveness of industry specialist auditors in mitigating REM practices. The results have implications for policy makers to enhance the current regulation structure of auditing and accounting professions. The results also provide new insights into the association between audit quality, REM and auditor independence in an emerging economy
ASSESSMENT OF ROAD TRAFFIC NOISE IN SELECTED URBAN RESIDENTIAL AND CONSTRUCTION AREAS

The work presented in this paper includes a field investigation of road traffic noise between residential and construction areas in a selected urban area. The aim of this study was to assess the level of noise pollution from road traffic noise in Seri Kembangan, Selangor. Therefore, this study included measurements of traffic noise level, evaluation of the percentage traffic volume between residential and construction areas; and identification of the correlation between traffic volume and traffic noise level. An EXTECH 407764 sound level meter was used to take noise level measurements for 1 hour and 30 minutes in one-minute intervals at both study sites. The parameter collected in the noise level monitoring was average noise level (LAeq). The traffic volume study was conducted using manual counts for 30 minutes. Four types of vehicles were counted, namely cars, vans, motorcycles, and heavy vehicles. Based on statistical analysis, it can be concluded that both sites had high traffic noise levels which exceeded the maximum permissible limit of 60 dBA during daytime, according to Malaysian guidelines, due to several factors. The findings show that road infrastructure such as noise barriers need to be further implemented, especially in residential areas. Mitigation of noise pollution must be further carried out by contractors. Additionally, further investigations need to be conducted by the relevant authorities to reduce the level of noise which may affect the quality of life for the communities in the area.
What factors underlie burden tolerance in South Korea? Policy implementation domain, administrative efficiency, and bureaucratic personality

ABSTRACT Although administrative burden has been studied in relation to social policy, the experience of policy implementation as onerous is relevant to all policy domains, and citizens can experience burden in virtually any encounter with the state. Moreover, perceptions of administrative burden can be influenced by administrative values, such as efficiency. Burden tolerance captures an individual’s belief that the compliance, learning, and psychological costs associated with policy implementation are legitimate and functional, and consequently their willingness to impose these costs on policy targets. We hypothesise that burden tolerance is conditioned by both policy implementation domain and the efficiency of the implementing organisation. Additionally, we link bureaucratic personality, or the tendency to view rules as intrinsically desirable and legitimate, to burden tolerance. We test our hypotheses using a representative sample of South Korean citizens and a survey experiment. Our results suggest that, first and contrary to our expectations, policy domain does not affect burden tolerance. Second, knowledge about inefficiency negatively affects tolerance. Third, bureaucratic personality is positively related to tolerance. We also discuss the contextual aspects of administrative burden, and particularly how the East Asian and Korean policy context may have implications for the generalisability of the administrative burden concept.
A Symmetry for Resolution of the Gauge Hierarchy Problem without SUSY, Null Higgs Condensate Energy, and Null Zero Point Energy

Alternative forms for solutions of the quantum field equations and their implications for physical theory, are considered. Incorporation of these alternative solutions, herein deemed supplemental solutions, into the development of quantum field theory leads to simple resolutions of more than one extant problem in high energy physics and quantum cosmology. The symmetry between the traditional and supplemental solutions results in a direct and natural zero-point energy value of zero, and, as well, a possible mechanism for cancelling the Higgs condensate energy, thereby providing a potential resolution of the large cosmological constant problem. Further, this symmetry may also resolve the Higgs gauge hierarchy problem. Resolutions of seeming theoretic impediments to supplemental fields, in particular, non-positive definite Fock space metric and vacuum decay, are presented. As the traditional-supplemental symmetry is already inherent in quantum field theory, it requires no extension to the fundamental mathematics of the theory.