Miracle-dz/UniFAR-FTUs huggingface dataset:
Observation of organic matters concentrations in agricultural runoff in the Red River Delta (Vietnam)

Due to utilization increase of chemical fertilizers and manures and of a large water volume for irrigation, agricultural runoff has significantly accelerated water pollution. The Red River locates in Vietnam where agriculture plays an important role in the country’s economy. This paper presented the observation results of organic matters concentrations in agricultural runoff from different plant fields (vegetable, flower and rice) in the Red River Delta in 2013 -2014. The results showed that DOC concentrations varied in a high range from 1.0 mg.L-1 to 37.1 mg.L-1, averaging 10.2 ± 6.2 mg.L-1 whereas POC concentrations varied from 0.5 to 4.5 mg.L-1, averaging 1.7 ± 0.7 mg.L-1 for a total 104 samples observed. TOC concentrations in water from the vegetable and flower fields (11.7 ± 7.3 mg.L-1 and 12.6 ± 6.0 mg.L-1 respectively) were higher than the one from the rice field (8.5 ± 6.6 mg.L-1). Lower organic matters concentrations were found in the rainy season than in the dry season due to dilution process. The results suggest the needs for regularly monitoring and efforts to control organic matter pollution from agricultural runoff in the Red River basin or other river basins in developing countries. Do sử dụng phân bón và thể tích nước tưới lớn, canh tác nông nghiệp đã và đang góp phần đáng kể gây ô nhiễm nguồn nước. Sông Hồng nằm ở Việt Nam, nơi ngành nông nghiệp đóng vai trò quan trọng trong nền kinh tế. Bài báo trình bày kết quả quan trắc hàm lượng cacbon hữu cơ (TOC) bao gồm dạng hòa tan (DOC) và không tan (POC), trong nước chảy tràn từ đất canh tác (rau, hoa, lúa) ở đồng bằng sông Hồng năm 2013 -2014. Kết quả cho thấy DOC thay đổi rất rộng từ 1,0 mg.L-1 đến 37,1 mg.L-1, trung bình đạt 10,2 ± 6,2 mg.L-1 trong khi POC thay đổi từ 0,5 mg. L-1 đến 4,5 mg.L-1, trung bình đạt 1,7 ± 0,7 mg.L-1 đối với 104 mẫu nước. TOC từ trồng rau và hoa (11,7 ± 7,3 mg. L-1 và 12,6 ± 6,0 mg.L-1) cao hơn so với trồng lúa (8,5 ± 6,6 mg. L-1). TOC trong mùa mưa thấp hơn so với mùa khô. Cần thường xuyên giám sát và nỗ lực kiểm soát ô nhiễm chất hữu cơ do nước chảy tràn từ đất canh tác ở lưu vực sông Hồng.
ALUNG February 22/2

JAMES H. FISHER,1 VLADIMIR SHEFTELYEVICH,1 YE-SHIH HO,2 SUZANNE FLIGIEL,3 FRANCIS X. MCCORMACK,4 THOMAS R. KORFHAGEN,5 JEFFREY A. WHITSETT,5 AND MACHIKO IKEGAMI5 1Pulmonary/Critical Care Medicine, Denver Health Medical Center and University of Colorado Health Sciences Center, Denver, Colorado 80262; 5Division of Pulmonary Biology, Children’s Hospital Medical Center, and 4Pulmonary and Critical Care Medicine, University of Cincinnati School of Medicine, Cincinnati, Ohio 45229-3039; 2Institute of Chemical Toxicology, Wayne State University, and 3Department of Pathology, John D. Dingell Veterans Affairs Medical Center, Detroit, Michigan 48201
DOES BANKING COMPETITION ALLEVIATE OR WORSEN CREDIT CONSTRAINTS FACED BY SMALL AND MEDIUM ENTERPRISES? EVIDENCE FROM CHINA By

Banking competition may enhance or hinder the financing of small and medium enterprises. Using a survey on the financing of such enterprises in China, combined with detailed bank branch information, we investigate how concentration in local banking market affects the availability of credit. We find that lower market concentration alleviates financing constraints. The widespread presence of joint-stock banks has a larger effect on alleviating these constraints, than the presence of city commercial banks, while the presence of state-owned banks has a smaller effect. (83 words) JEL Classification: D41; D43; G21
AHEART May 45/5

Chen, Li-Wen, Chau-Fong Chen, and Yih-Loong Lai. Chronic activation of neurokinin-1 receptor induces pulmonary hypertension in rats. Am. J. Physiol. 276 (Heart Circ. Physiol. 45): H1543–H1551, 1999. —In this study we explored the hypothesis that chronic activation of neurokinin-1 (NK-1) receptor induces pulmonary hypertension in Wistar rats. First, the activation of NK-1 receptor on the pulmonary circulation was investigated by use of a chronic injection of NK-1 agonist [Ser,Met(O2)]-substance P (1 3 1029 mol/kg) for 2 wk at sea level (rats breathed room air) and during hypoxia (rats were placed in a hypobaric 380-Torr chamber). Second, we studied the effect of NK-1 antagonist (CP-96345) on developing and developed (after 4 wk of chronic hypoxia) pulmonary hypertension. Pulmonary arterial pressure, the weight ratio of right ventricle to left ventricle 1 septum, hematocrit, and substance P (SP) were measured. We found that NK-1 agonist significantly increased pulmonary arterial pressure in the sea-level but not in the hypoxic group. However, NK-1 agonist induced neither right heart hypertrophy nor polycythemia. CP-96345 significantly decreased pulmonary arterial pressure in the hypoxic group but had no effect in the sea-level group. Furthermore, CP-96345 significantly attenuated the acute SP-induced increase in pulmonary arterial pressure in the sea-level and hypoxic groups, with a larger increase in the hypoxic group. These results suggest that chronic activation of NK-1 receptor induces pulmonary hypertension and that there is an increase in the sensitivity of pulmonary vessels in response to SP in chronically hypoxic rats.
Sustainable and environmentally friendly reinforced soil slopes and walls constructed with draining geogrids: recent UK experience

Research has shown that geotechnical engineers and the construction industry in general like to think of themselves as working to benefit the environment and providing for future generations in tandem, if not always in harmony, with nature. However, engineers still prefer to work with high quality and expensive imported granular fill, rather than seriously consider using recycled spoil generated as part of construction activities. Engineers can design reinforced soil structures using marginal poorly drained fills without the need to import granular fill, which has both cost and environmental implications. Marginal fills typically have high silt and/or clay contents which, when loaded, have the potential to generate excess pore water pressures in the structural backfill. Poor drainage in the structural fill reduces the available strength of the fill, thus reducing the bond between the fill and the geogrid reinforcement. Therefore, to use marginal fill efficiently, adequate drainage must be provided in the reinforced soil structure. By using a novel geocomposite that combines reinforcement and drainage into a geogrid sustainable and environmentally friendly slopes and walls can be designed and constructed. Between 2015 and 2017 an innovative design methodology and approach for the construction of reinforced slopes and walls, up to 17m in height, with low-permeability fills was successfully used in the UK. The design and construction experience gained in the UK is presented to confirm the effectiveness of the system and given engineers confidence in the use of marginal fills in reinforced soil systems.
EFFECT OF CRYOGENIC TREATMENTS ON MECHANICAL PROPERTIES OF 7075 ALUMINUM ALLOY MATRIX/AL2O3 PARTICLES REINFORCED COMPOSITES

Aluminum alloy7075was used as base material to the metal matrix composites (MMMCS) with different wt % of Al2O3. (0.2, 0.4, 0.6, 0.8, and 1), the size of Alumina reinforced material particles is 10 Nano meter, were fabricated using stir casting technique. The effect of cryogenic treatments on adding Al2O3 nano particles content on the mechanical properties of the MMMCS. It was observed that the nanomaterial reinforcement led to high improvement in ultimate strength ( ), yield stress ( ), BHN hardness and ductility the improvements were due to good distribution of Al2O3 and refinement of base metals matrix aluminum grains. The maximum improvement in ultimate strength, yield stress and BHN hardness was observed at 0.2 wt %. Al2O3. While the minimum value of Elongation % was obtained at 0.2 wt. % Al2O3.
Syndrome-linked CK 2 α mutations have reduced kinase activity

The Okur-Chung Neurodevelopmental Syndrome, or OCNDS, is a newly discovered rare neurodevelopmental disorder. It is characterized by developmental delay, intellectual disability, behavioral problems (hyperactivity, repetitive movements and social interaction deficits), hypotonia, epilepsy and language/verbalization deficits. OCNDS is linked to de novo variants in CSNK2A1, that lead to missense or deletion/truncating mutations in the encoded protein, the protein kinase CK2α. Eighteen different missense CK2α mutants have been identified to date, however no biochemical or cell biological studies have yet been performed to clarify the functional impact of such mutations. Here, we show that 15 different missense CK2α mutations lead to varying degrees of loss of kinase activity as recombinant purified proteins and when mutants are ectopically expressed in mammalian cells. We further detect changes in the phosphoproteome of three patient derived fibroblast lines and show that the subcellular localization of CK2α is altered for some of the OCNDS-linked mutants and in patient derived fibroblasts. Our data argue that reduced kinase activity and abnormal localization of CK2α may underlie the OCNDS phenotype.
Saccharomyces cerevisiaeplasmamembranenutrient sensors and their role inPKA signaling

The ability to elicit a fast intracellular signal leading to an adaptive response is crucial for the survival of microorganisms in response to changing environmental conditions. Therefore, in order to sense changes in nutrient availability, the yeast Saccharomyces cerevisiae has evolved three different classes of nutrient-sensing proteins acting at the plasma membrane: G protein-coupled receptors or classical receptor proteins, which detect the presence of certain nutrients and activate signal transduction in association with a G protein; nontransporting transceptors, i.e. nutrient carrier homologues with only a receptor function, previously called nutrient sensors; and transporting transceptors, i.e. active nutrient carriers that combine the functions of a nutrient transporter and receptor. Here, we provide an updated overview of the proteins involved in sensing nutrients for rapid activation of the protein kinase A pathway, which belong to the first and the third category, and we also provide a comparison with the best-known examples of the second category, the nontransporting transceptors, which control the expression of the regular transporters for the nutrient sensed by these proteins.
SUSTAINABLE MANAGEMENT PRACTICES FOR BROODSTOCK DEVELOPMENT, INCUBATION AND HATCHING OF MACROBRACHIUM ROSENBERGII USING PROBIOTICS IN A MODEL HATCHERY OF BANGLADESH

The influences of probiotics Sanolife MIC comparing with antibiotics OTC were tested in both water quality and growth parameters for the brood-stock development, incubation and hatching of Macrobrachium rosenbergii. The study was to find out a sustainable practice of hatchery management applying probiotics instead of using antibiotics frequently. Influences of the application of three doses, Sanolife MIC @0.50, 0.65 and 0.80 ppm in water were checked in egg incubation, spawning and hatching phases. Sanolife Pro-1 @4 ppm was used in the feed of brood-stock as a supporting gut-probiotic in all the three trials with MIC. Findings of MIC based trials were compared with a control group of treatments with antibiotic OTC (@4.0 ppm in favor of the objectives of the study. Among three doses as 0.50, 0.65 and 0.80 ppm of MIC, the dose 0.65 ppm was found to be best in respect to the findings of the study. Water pH, DO, NH3, NO3 and NO2 level were found to be comparatively more stable and more favorable in probiotics based trials than that of antibiotic. Increased feeding appetite of spawners, earlier (4 days) embryonic development, higher (9%) hatching rate, 3% less disability of new hatchlings, better physical condition and higher (10%) rate of attraction to illumination of new hatchlings and absence of disease contamination in probiotic based trial (trial with 0.65 ppm) revealed much better efficiency and sustainability of using probiotics than that of antibiotic in rearing phases of berried prawn brood-stocks.
Characterisation of cardiac pathology in 23 autopsies of lethal <fc>COVID</fc>â•’19

While coronavirus disease 2019 (COVID-19) primarily affects the respiratory tract, pathophysiological changes of the cardiovascular system remain to be elucidated. We performed a retrospective cardiopathological analysis of the heart and vasculature from 23 autopsies of COVID-19 patients, comparing the findings with control tissue. Myocardium from autopsies of COVID-19 patients was categorised into severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) positive (n = 14) or negative (n = 9) based on the presence of viral RNA as determined by reverse transcriptase polymerase chain reaction (RT-PCR). Control tissue was selected from autopsies without COVID-19 (n = 10) with similar clinical sequelae. Histological characteristics were scored by ordinal and/or categorical grading. Five RT-PCR-positive cases underwent in situ hybridisation (ISH) for SARS-CoV-2. Patients with lethal COVID-19 infection were mostly male (78%) and had a high incidence of hypertension (91%), coronary artery disease (61%), and diabetes mellitus (48%). Patients with positive myocardial RT-PCR died earlier after hospital admission (5 versus 12 days, p < 0.001) than patients with negative RT-PCR. An increased severity of fibrin deposition, capillary dilatation, and microhaemorrhage was observed in RT-PCR-positive myocardium than in negatives and controls, with a positive correlation amongst these factors All cases with increased cardioinflammatory infiltrate, without myocyte necrosis (n = 4) or with myocarditis (n = 1), were RT-PCR negative. ISH revealed positivity of viral RNA in interstitial cells. Myocardial capillary dilatation, fibrin deposition, and microhaemorrhage may be the histomorphological correlate of COVID-19-associated coagulopathy. Increased cardioinflammation including one case of myocarditis was only detected in RT-PCR-negative hearts with significantly longer hospitalisation time. This may imply a secondary immunological response warranting further characterisation.
Estimation of Heterosis and Combining Ability for Some White Maize Inbred Lines Using Half-Diallel Crossing

Eight S7 white maize inbred lines were derived from selfing of S5 inbred lines of two populations, i.e., Giza-2 and IW-469 were chosen to be used as parents of a half-diallel crossing and obtained on 28 F1 crosses, which evaluated along with the 2 check hybrids at Experimental Farm, Faculty of Agriculture, Al-Azhar University, Assiut Branch in 2021 to identify the best parental general combiners and specific combinations to improve maize for earliness and yield. Results manifested that highly significant differences were detected among crosses for all the studied traits. Also, means squares due to GCA and SCA were highly significant for all traits. The ratio of σGCA/σSCA was less than one for all traits. The 4 crosses; P1 x P4, P3 x P6, P5 x P6 and P7 x P8 possessed desirable significant positive heterotic effects for increasing grain yield/plant relative to the checks SC136 and SC-10, and among them the cross P3 x P6, also possessed significant negative desirable standard heterotic effects for tasseling and silking earliness relative to both the check hybrids. The parent P8 possessed significant desirable GCA effects for grain yield and its components with silking earliness. The 14 crosses; P1 × P2, P1 × P4, P1 × P5, P1 × P8, P2 × P3, P2 × P8, P3 × P4, P3 × P6, P3 × P7, P3 × P8, P4 × P5, P5 × P6, P5 × P7 and P7 × P8 possessed significant positive desirable SCA effects for high yielding ability and among them the 2 crosses; P1 × P8 and P2 × P3, also possessed significant desirable SCA effects for tasseling and silking earliness.
Comparative Study Of Decision Making Techniques For Multi-Attribute Decision Making Problems

The selection of the method of decision-making in order to determine the expected outcomes of the solution of the case of multi attributes is difficult because faced with the problems associated with the subjectivity and inconsistency of the results of the calculation. Therefore, scientists continue to develop a variety of approaches in order to produce the proper method with a minimal degree of subjectivity from the decision maker. This article discusses the literature review three methods of decision making by utilizing the weighting of the criteria in determining the outcome of the decision process. They are Analytical hierarchy process (AHP), TOPSIS and PROMETHEE. The discussion in this article is not intended to discredit one or several existing methods, however, because the presence of these three methods has provided significant benefits in the process of determining an alternative to the concept of decision support systems, and in certain cases subjectivity is required in the absence of mathematical procedures specific to describe human creative process in assessing something.
High Voltage Special Issue: Thermally Conductive but Electrically Insulating Materials For High Voltage Applications Heat conductive h-BN/CTPB/epoxy with enhanced dielectric properties for potential high-voltage applications

To enhance the toughness and electrical insulation properties of cured epoxy, carboxyl-terminated polybutadiene (CTPB) liquid rubber was used to modify epoxy in this study, and the thermal conductivity, mechanical and dielectric properties of modified epoxy were investigated. The results indicate that the CTPB-epoxy exhibits higher impact strength and lower dielectric constant and loss compared with pure epoxy. Further, hexagonal boron nitride (hBN) was used to reinforce epoxy modified with 20 phr CTPB. It is found that compared with the hBN/epoxy under the same filler loading, the heat conductive hBN/CTPB/epoxy possesses a lower dielectric permittivity and dissipation factor in all frequency ranging from 102–107 Hz, a higher electrical resistivity and dielectric breakdown strength, and improved mechanical toughness. Therefore, the prepared hBN/CTPB/epoxy composites are potentially useful in practical electrical insulation applications.
Transparency in the Municipal Public Management: An Evaluation of Rio Grande do Sul State’s Municipalities

The objective of the present study is to determine the transparency level of Rio Grande do Sul state’s municipalities, identifying the variables that explain it. This is a documental and quantitative research, observing the most recent information disclosed in the state’s transparency websites, identifying if the data disclosure is correct, through the Municipal Public Management’s Transparency Index, as well as the regression analysis and descriptive statistics. In this way, it is possible to observe that most state’s municipalities present an average level of transparency. Besides, it was observed that, from the eleven socioeconomical variables that were analyzed, only five are capable of influencing the transparency index. Therefore, many measures must still be adopted by the state’s municipal managements, so that they enforce the Access to Information Law and fulfill all of the aspects that come from the transparency.
XEN ® Gel Stent: A Comprehensive Review on Its Use as a Treatment Option for Refractory Glaucoma

: The XEN Gel Microstent is a subconjunctival microinvasive glaucoma surgical device developed with the aim of improving the predictability and safety pro ﬁ le of bleb-forming glaucoma surgical procedures. The stent is a hydrophilic tube composed of a porcine gel cross-linked with glutaraldehyde with good stability and biocompatibility with minimal tissue reaction. This device has demonstrated promising outcomes with fewer risks compared to traditional surgeries. The aim of the review is to present early studies on different designs of the XEN Gel Stent, to summarize different surgical techniques of implantation and to analyze more comprehensively the results, complications and rates of needling of the commercially available device (Xen 45). The review will address separately special cases (PXG, UVG, ICE, congenital glaucoma) and describe small series and case reports.
ArticleSubstitution effects on the optoelectronic properties of Coumarin derivativesAmit Kumar1*

Coumarin derivatives have gathered major attention largely due to their versatile utility in a wide range of applications. In this framework, we report a comparative computational investigation on the optoelectronic properties of 3-phenylcoumarin and 3-heteroarylcoumarin derivatives established as enzyme inhibitors. Specifically, we concentrate on the variation in the optoelectronic characteristics for the hydroxyl group substitutions within the coumarin moiety. In order to realize our aims, all-electron density functional theory and time dependent density functional theory calculations were performed with a localized Gaussian basis-set matched with a hybrid exchange–correlation functionals. Molecular properties such as highest occupied molecular orbital (HOMO) and lowest unoccupied molecular orbital (LUMO) energies, vertical ionization (IEV) and electron affinity energies, absorption spectra, quasi-particle gap, and exciton binding energy values are examined. Furthermore, the influence of solvent on the optical properties of the molecules is considered. We found a good agreement between the experimental (8.72 eV) and calculated (8.71 eV) IEV energy values for coumarin. The computed exciton binding energy of the investigated molecules indicated their potential optoelectronics application.
New Cooperation and Novel Innovations: The Role of Regional Brokerage and Collaboration Intensity

Along with the increased importance of technology innovation, the importance of collaboration has been highlighted for conducting the innovation. This study discusses the importance of brokerage role of regions in co-inventor collaboration for establishing novel innovation and new collaboration. In addition, we address how regional collaboration intensity interacts with the brokerage role, highlighting its mediating effect. For this purpose, empirical analysis has been conducted with EPO PATSTAT database and European Regional Database (ERD) covering the European regions between 1986 and 2015. Our finding shows that the brokerage roles contribute to the extension of collaboration network, but are not efficient for the creation of new invention. Collaboration intensity, however, helps both novel innovation and new collaboration, and especially it positively interacts with brokerage role indicating that a region can take the benefit from being broker in collaboration. JEL Classification: O31, R11, D85
JJesign Problems: II

Several Global Positioning System (GPS) receivers were reviewed and human factors problems associated with the user interface were noted. The problems documented below include specific control and display problems, design inconsistencies across units, and general design problems that apply to all of the units reviewed. Discussing these problems highlights the need to make pilots aware of issues that may require specific training or other preventive measures. Recommendations for design improvements are provided.