Miracle-dz/UniFAR-FTUs huggingface dataset:
Prognostication of Canine T Cell Lymphoma

Prognostication of Canine T cell Lymphoma Nariman Deravi University of Guelph, 2017 Advisor: Dr. Dorothee Bienzle Canine lymphoma is a heterogeneous disease with many different subtypes. T cell lymphoma (TCL) is variable in outcome, and includes subtypes with non-progressive, indolent and aggressive disease course. Methods used to categorize lymphoma including cytopathology, flow cytometry, histopathology, and immunochemistry. Many different classification schemes have been used in the past, however, currently an adaptation of the human World Health Organization (WHO) classification is proposed. This classification categorizes lymphoma based on cytopathology, flow cytometry, histopathology, immunohistochemistry, and molecular techniques. Association of immunotype and subtype with disease course is incompletely defined. The goal of this study was to associate immunotype and different WHO subtypes with prognosis. Retrospectively, flow cytometric immunotyping for 127 canine TCL were analyzed in relation to survival and progression free interval. Samples originated from 101 multicentric, 8 mediastinal, 6 cutaneous, 5 hepatosplenic, 5 gastrointestinal and 2 other anatomic subtypes of TCL. Compared to patients with multicentric TCL, those with gastrointestinal lymphoma had shorter survival and progression free interval, and those with hepatosplenic lymphoma had shorter progression free interval. Among patients with multicentric TCL, immunotypes of CD4/CD8 /MHCII, CD4/CD8/MHCII and CD4/CD8/MHCII were associated with longer survival than the CD4/CD8/MHCII immunotype, and immunotypes of CD4/CD8/MHCII, CD4 /CD8/MHCII, and CD4/CD8/MHCII were associated with longer progression free intervals. Prospectively, cytopathological, flow cytometric, histopathological, and immunohistochemical data was collected from 16 patients. Samples included 8 peripheral T cell Lymphoma – not otherwise specified (PTCL-NOS), 6 T zone lymphomas (TZL), and 2 T lymphoblastic lymphomas (T LBL). Both aggressive and indolent forms were identified in the PTCL-NOS and T LBL categories with unique immunotypes consistent with the retrospective study. TZL were always indolent and had consistent immunotypes. MHC class II expression was associated with favourable prognosis. Grading based on mitoses or Ki67 expression did not significantly affect outcome. Interobserver agreement was non-existent for cytopathology and flow cytometry, and
Design of targeted photosensitizer-conjugates towards Neuropilin-1 and folate receptors for improving the selectivity of anti-cancer photodynamic therapy

Photodynamic therapy (PDT) is a type of cancer therapy that could offer many advantages. One possible way to improve the effectiveness of PDT is the elaboration of third generation photosensitizers (PSs) which consisted of PSs coupled with targeting agents. This thesis focuses on improving the selectivity of PS delivery through designing targeted PS agents. The first part of the thesis deals with the study of a PS-folic acid (PS-FA). FA is a well-known targeting unit which bonds with high efficiency to folic acid receptor over-expressed on the surface of many cancer cells. We particularly checked the stability of folic acid under the influence of environmental factors. The second part is devoted to the study of KDKPPR peptide designed to target neuropilin-1, a receptor over-expressed in neovessels. Several modifications of the peptide were made and the analogues were tested through ELISA assays to evaluate their binding capability following the modifications. The third part of the thesis is related to the synthesis of porphyrin and peptide building blocks through click chemistry technique to form multiple conjugates with different numbers of porphyrins and peptides attached to the platforms
Sawn-timber and kraft pulp properties of Pinus elliottii × Pinus caribaea var. hondurensis and Pinus patula × Pinus tecunumanii hybrids and their parental species

A study was undertaken to evaluate the quality of the timber produced by Pinus elliottii × Pinus caribaea var. hondurensis (PECH) and the Pinus patula × Pinus tecunumanii low elevation (PPTL) and high elevation (PPTH) hybrids and their parent species for both kraft pulp and sawn-timber production. Trees were taken from unthinned tree improvement trials managed for pulpwood, ranging in age between 15 and 19 years. All sawn boards produced by study trees met the minimum wood density requirement for S5-grade structural timber (360 kg m−3), but approximately 17% of the boards failed to meet the other requirements for the grade, largely due to knot-related defects. Results of dynamic modulus of elasticity assessments performed on all of the boards suggested that a large percentage of boards would not meet the specified average stiffness (7 800 MPa). This was confirmed by the results of static bending tests performed on a subsample of boards. All boards tested for all species and hybrids met the required fifth percentile bending strength value for grade S7 (15.8 MPa) according to SANS 6122 (2008) specifications. The kraft pulping results indicated that the samples taken from the upper part of the stem yielded slightly better results on average than the samples representing the whole tree with respect to uniformity in the kappa vs charge and temperature, and yield vs kappa traits, with slight improvement of pulp yield (52% vs 50%) and some strength properties compared with whole tree pulping. Samples from the upper part of the stem had a close delignification rate in the 60–80 kappa range. The delignification rate for PPTL in the 60–80 kappa range was slower and the yield was slightly lower than P. patula (53.17% vs 52.72%) despite a higher kappa number. The pulp strengths short-span compressive test, breaking length and tearing strength of PECH were similar to those of P. elliottii, which were in turn generally lower than those of P. patula. The pulp strengths of PPTL and PPTH were similar to those of P. patula, whereas P. caribaea strengths were intermediate between those of P. patula and P. elliottii. With the exception of a slightly lower pulp yield, PPTL emerged as the best all-round hybrid for both pulp and sawn-timber properties.
Incidence and within field dispersion pattern of pod borer, Helicoverpa armigera (Lepidoptera: Noctuidae) in chickpea in Ethiopia

Abstract Podborer is a major pest of chickpea in Ethiopia. Field surveys were conducted in 2013/2014 and 2014/2015 in central and northwestern Ethiopia to assess the prevalence and within field distribution of the pest. Although podborer was prevalent throughout the surveyed areas, there was a significant difference in larval density (0.10–3.75 larvae per m2) among zones and districts within zones. This variation was attributed to cropping history, cropping patterns, chickpea-crop adjacency, and weather (rainfall and temperature) conditions before and during the season as well as control measures applied. The optimum sample size required for precision ranged from 98, when podborer density was 10/m2, to 1045, when podborer density was ≤1/m2. Within field distribution of the larvae fitted a negative binomial distribution indicating that the larvae had a clumped/aggregated dispersion pattern. These results will enable chickpea stakeholders to develop and apply appropriate integrated crop management techniques for the control of podborer.
Vegetable Soybean Tolerance to Pyroxasulfone

If registered for use on vegetable soybean, pyroxasulfone would expand the options for weed management systems in the crop. In order to determine the potential crop injury risk of pyroxasulfone on vegetable soybean, the objective of this work was to quantify vegetable soybean tolerance to pyroxasulfone applied PRE and EPOST. Twenty-one vegetable soybean and two grain-type soybean cultivars were treated with pyroxasulfone at 417 g ai ha-1 (twice the recommended field use rate) PRE, EPOST, or not treated. Plant population density was unaffected by pyroxasulfone. Only low levels (<10%) of crop injury were observed within a few weeks after PRE and EPOST treatments. Soybean cultivars were not differentially affected by pyroxasulfone, as evidenced by the lack of interactions between cultivar and treatment for any crop response variable. The low amount of risk of crop injury associated with pyroxasulfone is no different for vegetable soybean cultivars grown in the US for commercial production than grain-type soybean. Nomenclature: Bentazon; fomesafen; imazamox; linuron; pyroxasulfone; sulfentrazone; soybean, Glycine max (L.) Merr.
Organic carbon patterns and budgets in the Long Island Sound estuary

A multi‐year observational time series was evaluated across the 150 km central axis of the U.S. east coast's Long Island Sound (LIS) estuary, in three distinct regions. Fluxes were calculated at the boundaries of the regions using observations coupled to a hydrodynamic model and applied to a mass balance to assess organic carbon (OC) export from LIS. For all years, during stratified summer periods, LIS was a net exporter of OC to the continental shelf. LIS annual net carbon export however, varied with river flow. The heterotrophic or autotrophic nature of LIS also shifted inter‐annually. During the mass balance analysis period (2009–2012), LIS ranged between net OC import from the continental shelf and heterotrophy in the lowest river flow year (2012) and net export of OC and autotrophy in the highest flow year (2011). Analysis suggests that LIS switches from net OC import to export when the annual river inputs exceed 19 km3 yr−1. Applying these thresholds to the annual river flow record suggests that net import occurred in 15% of the last 20 years and that LIS usually is a net exporter of OC (85%). Annually averaged LIS carbon export values based on river flow conditions over the last 20 yr are estimated at 56 ± 64 × 106 kg yr−1. Analysis also suggests that LIS shifts from net heterotrophic to net autotrophic when annual river flow exceeds 26 km3 yr−1 (35% of the last 20 yr). Net heterotrophic conditions are most common, representing 65% of the last 20 yr.
AZOLLA- AN ALTERNATE AND SUSTAINABLE FEED FOR LIVESTOCK

Azolla is very rich in proteins, essential amino acids, vitamins (vitamin A, vitamin B12, Beta Carotene), growth promoter intermediaries and minerals like calcium, phosphorous, potassium, ferrous, copper, magnesium etc. Azolla, on a dry weight basis, is constituted of 25-35% protein content, 10-15% mineral content and 7-10%, a combination of amino acids, bio-active substances and biopolymers. Carbohydrate and oil content in Azolla is very low. Thus the biocomposition of Azolla, makes it one of the most economic and efficient feed substitutes for livestock. Moreover, Azolla can be easily digested by livestock, owing to its high protein and low lignin content. Azolla can also be fed to sheep, goat, pig and rabbit as feed substitute.
The Documentary Film

Although documentary is defined as the genre of cinema closest to reality, the presentation of reality on the screen is a problem in itself. The reality of the physical world is recreated on the screen according to the choice made by the producer through the receiver/camera. Due to the nature of the medium, it cannot be known to what extent these elections represent the truth. The search for reality/emphasis that each of the documentary film movements have defended in their own discourses leads to semantic confusion due to the unknown nature of truth. The main difficulty in classifying documentary genres lies in this confusion of concepts. Both translations of concepts into our own language and the meanings they correspond to in other languages often do not fully correspond to each other. This situation makes it difficult to classify documentary film forms under certain sub-headings. Another factor lies in the fact that the concept of truth cannot be fully understood and defined. Finding the reality of documentaries is often a matter of ethical values for the filmmaker who produced the documentary. For this reason, the search for truth, which the director defended in his documentary film, is a problem associated with the subjective ethical values that he adheres to, so he is always open to criticism and questions. In this study, based on the definition of documentaries and groundbreaking documentaries, the problem of reality in documentary films will be discussed through specific movements and films. As a result of this discussion, under the appropriate headings, it will be discussed whether the films that are questioned within the critical point of view reflect reality or not. As a result of the definitions and conclusions drawn, a generic table of classification of documentary genres will be created, and points to be considered in the classification will be clarified. This classification table is based on individual judgment and not on precise measurement and classification. The reasons for the qualitative evaluations that make up this individual judgment are explained in the relevant sections of the study together with the inferences made. This study has been prepared to show the source of the problems that will arise in other studies on the classification of documentary genres, and to provide information on how a certain classification should be made on this issue. кино, реальность кино, классификация.
Editorial

This issue of Signs takes up a subject-science-that is too often neglected or distorted by the new scholarship about women. The issue also appears at a crucial time in the development of that scholarship. Part of the politics of consciousness, the new scholarship has sought to drain some ideas of their power, to give others new strength. It has tried, as well, to change public institutions that shape the private mind. It has, during the past decade, grown enormously. ' However, despite that zeal and promise, it still provokes resistance. Although surliness has historically been a common response to any new, invigorating intellectual
MICROSATELLITE MARKERS (SRR) AS A TOOL TO ASSIST IN IDENTIFICATION OF EUROPEAN PLUM (PRUNUS DOMESTICA)

The aim of this study was, parallel to the usual morphological identification of cultivars, to fingerprint a subset of 45 European plum cultivars with 7 SSR primers, to determine if there was sufficient polymorphism to differentiate the cultivars. And furthermore, to establish one routine method for cultivar identification for European plums at the KOB, and then use this new method as a technique to differentiate two unknown samples, as well as examine the authenticity and purity of cultivars for the nursery industry. The 7 SSR markers generated a total of 140 alleles in the European plum. The number of alleles per locus ranged from 31 for EMPaS01 to 10 for EMPaS02 with an average of 20 alleles per locus. The polymorphism information content (PIC) for the 7 SSR loci varied from 0.857 to 0.94 with an average of 0.898. Based on the PIC values, primer pair EMPaS01 was the most informative while EMPaS02 was the least informative.
Flowering performance and yield of established and recent strawberry cultivars (Fragaria × ananassa) as affected by raising temperature and photoperiod

ABSTRACT Plants of six strawberry cultivars were raised under controlled conditions and tested for flowering and yield potential. Short days (SD) at intermediate temperatures for 4 weeks in August induced profuse flowering in subsequent long days (LD) in all cultivars except the late-flowering ‘Malwina’. LD conditions induced flowering only in ‘Nobel’, which has an everbearing parent. ‘Nobel’ and ‘Saga’ exhibited broad temperature adaptation for SD floral induction, which was generally reduced or suppressed at 9 and 27°C. After autumn planting, all cultivars flowered most abundantly in plants raised in SD and intermediate temperatures. Flowering was earliest in ‘Nobel’ and ‘Rumba’. Plants that did not reach floral commitment after 4 weeks in SD continued and completed induction under subsequent natural SD conditions after planting in the field, demonstrating the capability of fractional induction. Berry yield varied in parallel with flowering in the field and was always higher in plants raised under SD conditions. The traditional cultivars ‘Florence’ and ‘Sonata’ out-yielded the more recent cultivars. Some cultivars lost more than two thirds of their initiated flowers during the winter with obvious consequences for their yields. With proper raising management, acceptable yields were obtained after autumn planting even in a cool Nordic climate.
Dry weight loss in leaves of dominant species in a successional sequence of the Mesopotamian Espinal (Argentina)

Aim of study : To compare litter decomposition dynamics among different species within a single forest type and also between a single species in different forest successional stages. Area of study : Different forests of a known successional sequence of the Mesopotamian Espinal, placed in Villaguay Department, Entre Rios Province, Argentina. Material and methods : A standard “litter bags” technique was employed. Chemical analyses of C and N were performed for leaves. A regression analysis was applied and data were fitted to a double exponential model. Means estimated among forests and species within each forest were compared using the Tukey-Kramer test. Main results : The model predicted that leaves would completely mineralize in the mid-term. Leaf decomposition rate in different species (both in the Secondary forest and Mature forest) had dry matter residues in the following decreasing order: Acacia caven > Prosopis nigra > Prosopis affinis > Celtis ehrenbergiana. Research highlights : Successional stage was not found to be a factor determining the decomposition rate among species. Different decomposition rates, observed among different species, would not be attributed to initial quality of residues in terms of C and N, but would be associated with a positive feedback process related to nutrient cycle; thus, a greater decomposition would increase nutrient availability and, consequently, litterfall input.
Nutlet morphology and its taxonomic implication in some taxa of Lamiaceae in Egypt

Nutlet morphology of 28 taxa belonging to 15 genera of Lamiaceae were examined using light and scanning electron microscopy. The taxa included representatives of the three subfamilies Ajugoideae, Lamioideae and Nepetoideae which all collected especially from Sinai, Egypt. Morphological characters, including nutlet shape, color, size; hilum (shape, length x width and position); epidermal cell shape; anticlinal walls (level, undulation, thickness and secondary sculpture); outer periclinal cell walls (level and secondary sculpture) are presented. The reticulate type was the most common among the studied taxa. Four types of basic anticlinal cell wall boundaries were recognized and many different shapes of the outer periclinal cell wall were described. Nutlet ornamentation, shape, size, colour and particularly hilum characters proved to be good taxonomic characters for the Egyptian Lamiaceae taxa. A key for the identification of the investigated taxa based on nutlet characters is provided.
Strongly surjective maps from certain two-complexes with trivial top-cohomology onto the projective plane.

For the model two-complex $K$ of the group presentation $\mathcal{P}=\langle x,y\,|\,x^{k+1}yxy \rangle$, with $k\geq1$ odd, we describe representatives for all free and based homotopy classes of maps from $K$ into the real projective plane and we classify the homotopy classes containing only surjective maps. With this approach we get an answer, for maps into the real projective plane, for a classical question in topological root theory, which is known so far, in dimension two, only for maps into the sphere, the torus and the Klein bottle. The answer follows by proving that for all $k\geq1$ odd, $H^2(K;mathbb{Z})=0$ and, for $k\geq3$ odd, there exist maps from $K$ into the real projective plane which are strongly surjective. For $k=1$, there is no such a strongly surjective map. 55N25, 57M20.
Graph Random Neural Networks for Semi-Supervised Learning on Graphs

We study the problem of semi-supervised learning on graphs, for which graph neural networks (GNNs) have been extensively explored. However, most existing GNNs inherently suffer from the limitations of over-smoothing, non-robustness, and weak-generalization when labeled nodes are scarce. In this paper, we propose a simple yet effective framework---GRAPH RANDOM NEURAL NETWORKS (GRAND)---to address these issues. In GRAND, we first design a random propagation strategy to perform graph data augmentation. Then we leverage consistency regularization to optimize the prediction consistency of unlabeled nodes across different data augmentations. Extensive experiments on graph benchmark datasets suggest that GRAND significantly outperforms state-of-the-art GNN baselines on semi-supervised node classification. Finally, we show that GRAND mitigates the issues of over-smoothing and non-robustness, exhibiting better generalization behavior than existing GNNs. The source code of GRAND is publicly available at this https URL.
Regulation of the Invasive Plant Heracleum persicum by Private Landowners in Tromsø, Norway

In the city of Tromsø in northern Norway, invasive Tromsø palm (Norwegian: Tromsøpalme; English: Persian hogweed) is widespread. Although Tromsø palm has negative impacts on biodiversity and contains a phototoxic sap that burns human skin, it is also considered to be a local symbol of Tromsø city and is appreciated by many inhabitants. This study examined private landowners’ characteristics, perceptions, and landowners’ regulation of invasive Tromsø palm on their parcels on Tromsø Island in 2012 (vegetation season: May–September) to provide information concerning which landowner groups could be assisted by official regulation. Eleven key informants and 17 landowners were interviewed. Afterward, Tromsø palm on Tromsø Island was mapped using aerial photos and street-level photos from Google Maps®/Google Street View® and fieldwork verification. This distribution map was superimposed on a property map in a geographic information system to produce a map showing private parcels that contained Tromsø palm and associated neighboring parcels that did not contain Tromsø palm. Questionnaires were mailed to the 441 owners of the selected parcels, and 199 of the returned questionnaires were analyzed. Tromsø palm was more likely to be fully regulated/absent on a parcel that was inhabited (particularly if the owner lived on-site) and less likely to be fully regulated/absent if the parcel was jointly managed by several households. These findings indicate that authorities could focus their management efforts on supporting regulation efforts of those private landowners who own currently uninhabited or rented-out parcels and landowners of parcels jointly managed by several households. Furthermore, those landowners who found regulation measures against the plant on Tromsø Island important tended to have partly or fully regulated Tromsø palm on their plots. This might imply that information campaigns from authorities might encourage more landowners to regulate Tromsø palm. Nomenclature: Tromsø palm (Norwegian: Tromsøpalme; English: Persian hogweed); Heracleum persicum Fischer/H. laciniatum auct. scand. ; non Hornem.