Miracle-dz/UniFAR-FTUs huggingface dataset:
Polynomial-Type Lyapunov–Krasovskii Functional and Jacobi–Bessel Inequality: Further Results on Stability Analysis of Time-Delay Systems

To derive a less conservative stability criterion via Lyapunov-Krasovskii functional (LKF) method, in previous literature, multiple integral terms are usually introduced into the construction of LKFs. This article generalizes the results of previous literature by proposing a polynomial-type LKF, which contains the LKFs with multiple integral terms as special cases. In addition, a Jacobi–Bessel inequality is presented to bound the derivative of such LKF. As a result, an improved stability criterion of time-delay systems is established. Finally, two numerical examples are given to illustrate the effectiveness, and advantages of our method.
Chemically induced neurite-like outgrowth reveals a multicellular network function in patient-derived glioblastoma cells

ABSTRACT Tumor stem cells and malignant multicellular networks have been separately implicated in the therapeutic resistance of glioblastoma multiforme (GBM), the most aggressive type of brain cancer in adults. Here, we show that small-molecule inhibition of RHO-associated serine/threonine kinase proteins (ROCKi) significantly promoted the outgrowth of neurite-like cell projections in cultures of heterogeneous patient-derived GBM stem-like cells. These projections formed de novo-induced cellular network (iNet) ‘webs’, which regressed after withdrawal of ROCKi. Connected cells within the iNet web exhibited long range Ca2+ signal transmission, and significant lysosomal and mitochondrial trafficking. In contrast to their less-connected vehicle control counterparts, iNet cells remained viable and proliferative after high-dose radiation. These findings demonstrate a link between ROCKi-regulated cell projection dynamics and the formation of radiation-resistant multicellular networks. Our study identifies means to reversibly induce iNet webs ex vivo, and may thereby accelerate future studies into the biology of GBM cellular networks. Summary: ROCK inhibition significantly promotes the outgrowth of cell projections in glioblastoma multiforme stem-like models, which in turn enabled the de novo formation of multicellular networks.
Remdesivir Use in Patients Requiring Mechanical Ventilation due to COVID-19

Abstract Background Remdesivir has been associated with accelerated recovery of severe coronavirus disease 2019 (COVID-19). However, whether it is also beneficial in patients requiring mechanical ventilation is uncertain. Methods All consecutive intensive care unit (ICU) patients requiring mechanical ventilation due to COVID-19 were enrolled. Univariate and multivariable Cox models were used to explore the possible association between in-hospital death or hospital discharge, considered competing-risk events, and baseline or treatment-related factors, including the use of remdesivir. The rate of extubation and the number of ventilator-free days were also calculated and compared between treatment groups. Results One hundred thirteen patients requiring mechanical ventilation were observed for a median of 31 days of follow-up; 32% died, 69% were extubated, and 66% were discharged alive from the hospital. Among 33 treated with remdesivir (RDV), lower mortality (15.2% vs 38.8%) and higher rates of extubation (88% vs 60%), ventilator-free days (median [interquartile range], 11 [0–16] vs 5 [0–14.5]), and hospital discharge (85% vs 59%) were observed. Using multivariable analysis, RDV was significantly associated with hospital discharge (hazard ratio [HR], 2.25; 95% CI, 1.27–3.97; P = .005) and with a nonsignificantly lower mortality (HR, 0.73; 95% CI, 0.26–2.1; P = .560). RDV was also independently associated with extubation (HR, 2.10; 95% CI, 1.19–3.73; P = .011), which was considered a competing risk to death in the ICU in an additional survival model. Conclusions In our cohort of mechanically ventilated patients, RDV was not associated with a significant reduction of mortality, but it was consistently associated with shorter duration of mechanical ventilation and higher probability of hospital discharge, independent of other risk factors.
Effect of seed polymer coating on field performance and quality of pigeonpea [Cajanus cajan (L.) Millsp]

An experiment was conducted to study the response of pigeonpea to seed polymer coating on crop growth, seed yield and quality of pigeonpea [Cajanus cajana (L.) Millsp] during kharif of 2011-12. The experiment consisted of eight seed treatments with three replications were laid out in simple randomized block design. The results of the present investigation revealed that T8 (deltamethrin 2.8 EC at 0.3 ml/kg seeds+vitavax power at 3 g/kg seed+polymer seed coating at 5 ml/kg seeds) was found to be significantly superior in growth and yield parameters viz., plant height (206.78 cm), number of primary branches (18.12), number of secondary branches (25.16), number of pods/plant (231.33), pod yield per plant (78.85 g), seed yield per plant (40.35 g), seed yield/hectare (16.79 q/ha) as compared to untreated control. The laboratory studies on seed quality indicated that all the seed quality parameters viz., 100 seed weight, germination percentage, seedling length, seedling dry weight, vigor index and electrical conductivity were found to higher in seeds obtained from T8 compared to other treatments
Delayed peracute capture myopathy in a Himalayan Ibex Capra sibirica (Mammalia: Cetartiodactyla: Bovidae)

The present study focused on the capture myopathy as a fatal consequence of capture and rescue operation in an endangered Himalayan Ibex kid. The Ibex died 48 hours after being captured without showing specific clinical signs. Post-mortem examination revealed renal cortical necrosis, degeneration of tubular cells and congestion as the main histopathological findings in kidneys. Myocardial lesions consisted of multifocal degenerative changes of myofibres, hyalinization and nuclear degeneration with pyknosis. Skeletal muscles that appeared grossly normal showed mild to moderate degeneration and fragmentation with intermittent loss of striation. The pathological findings were indicative of delayed peracute capture myopathy. This is believed to be the first report of capture myopathy in an endangered Himalayan ibex from India underlining the importance of understanding the causes of mortality in such endangered wild species as a prerequisite to successful conservation programme.
Reciprocal hybridization between diploid Ficaria calthifolia and tetraploid Ficaria verna subsp. verna: evidence from experimental crossing, genome size and molecular markers

Ficaria is a taxonomically intriguing polyploid complex with high morphological variability. Both hybridization and polyploidization have been suggested as the main evolutionary forces behind the high morphological variability in this genus; however, detailed studies are lacking. In Central Europe, two Ficaria taxa (diploid F. calthifolia and tetraploid F. verna subsp. verna) occasionally co-occur in local sympatry, which might result in hybridization. We investigated sympatric populations of the two Ficaria taxa using flow cytometry, chromosome counts, AFLP analysis and plastid DNA sequencing; we also performed experimental homoploid and heteroploid crosses to determine the frequency and direction of hybrid triploid formation, an alternative route of triploid origin (autopolyploidy) and the possibility of a one-step neoallotetraploid origin. Sympatric populations were composed of three genetic clusters corresponding to diploid F. calthifolia (2n = 16), tetraploid F. verna subsp. verna (2n = 32) and triploid plants (2n = 24). The holoploid genome size and AFLP data suggest a hybrid origin of the triploids, thereby making their formation via autopolyploidization in F. calthifolia unlikely. The triploid populations are monoclonal and of independent origin. In contrast, the parental populations exhibit high genotypic diversity and frequent sexual reproduction, including those of predominantly asexual F. verna subsp. verna. Experimental crossing confirmed that both parental taxa produce fertile seeds via a sexual pathway, but not by apomixis, and that both serve as pollen acceptors in heteroploid crosses, which is consistent with the plastid sequencing. However, hybridization is asymmetric, with maternal-excess crosses being significantly more successful. No signs of neoautotetraploidization or neoallotetraploidization were detected. In summary, recent gene flow between the studied Ficaria taxa is either limited or absent.
INDOOR SHORT-TERM EXPOSURE TO AIRBORNE PARTICULATE MATTER FROM TRADITIONAL COOKSTOVES IN RURAL AREAS OF MALAWI. A CASE OF NSABWE AND BAULENI VILLAGES

This study was carried out to assess the short-term exposure to respirable particulate matter (PM2.5) from biomass combustion. A total of 24 households were sampled from two rural villages in Lilongwe, viz Nsabwe and Bauleni villages. Levels of particulate matter were measured using a portable gas detector. Indoor mean concentrations of PM2.5 ranged from 457 to 698 µg/m3, with no significant difference between the two villages, suggesting exposure to similar levels of airborne particulate matter. The observed levels are far above the recommended WHO limit for indoor air, posing a great health risk, more especially to the women and children who frequently visit the cooking areas. There is therefore need to widen appropriate intervention measures to reduce the current levels of indoor air pollution in the rural areas.
THE IMPACT OF EARNING PER SHARE AND RETURN ON EQUITY ON STOCK PRICE

Research conducted to determine the effect of Earning Per Share and Return on Equity on Stock Prices, a survey on the Nikkei 225 Index of issuers in 2018 on the Japan Stock Exchange. the number of issuers in this study was 57 issuers. The data taken is the 2018 financial report data. Based on the results of data processing with the SPSS version 25 program shows that Earning Per Share and Return on Equity affect the Stock Price of 67.3% and partially Earning Per Share has a positive effect on Stock Prices. Furthermore, Return on Equity has a negative effect on Stock Prices. If compared to these two variables, EPS has the biggest and significant influence on stock prices, however, Return on Equity has a negative effect on stock prices
Global education policy mobilities and subnational policy practice

ABSTRACT Drawing on data from three levels of education policy-making in Canada, in this paper we identify variegated interactions of global circulations of sustainability discourses in education in relation to priorities and responses at subnational levels of government, including provinces and territorial ministries of education, local school divisions, and schools. Understanding ‘scale’ as mutable and practiced vs. fixed, we discuss instances of policy recoding or mutation when global UN priorities have been shifted to reflect language or priorities suited to education ministries and school divisions; as well as examples of policy immobility, where subnational education bodies did not engage with UN sustainability approaches. Cases of policy amplification are also highlighted, in which school division policy priorities appeared to increase the influence of provincial policy. In some cases, intentional efforts of ‘rescaling’ seemed to influence policy responses, such as through processes of school division amalgamation, or the growing attempts to relocalise policy in Canada’s north. We draw on data from across six Canadian provinces and territories and 10 school divisions to better understand the mobilities of sustainability in education policy in relation to subnational policy practice, including via topological influences such as policy actors and certification programmes.
Necl-5/Poliovirus Receptor Interacts With VEGFR2 and Regulates VEGF-Induced Angiogenesis

Rationale:Vascular endothelial growth factor (VEGF), a major proangiogenic agent, exerts its proangiogenic action by binding to VEGF receptor 2 (VEGFR2), the activity of which is regulated by direct interactions with other cell surface proteins, including integrin αVβ3. However, how the interaction between VEGFR2 and integrin αVβ3 is regulated is not clear. Objective:To investigate whether Necl-5/poliovirus receptor, an immunoglobulin-like molecule that is known to bind integrin αVβ3, regulates the interaction between VEGFR2 and integrin αVβ3, and to clarify the role of Necl-5 in the VEGF-induced angiogenesis. Methods and Results:Necl-5-knockout mice displayed no obvious defect in vascular development; however, recovery of blood flow after hindlimb ischemia and the VEGF-induced neovascularization in implanted Matrigel plugs were impaired in Necl-5-knockout mice. To clarify the mechanism of the regulation of angiogenesis by Necl-5, we investigated the roles of Necl-5 in the VEGF-induced angiogenic response.
Genetic analysis of a heritage variety collection

Abstract Landraces (including heritage varieties) are an important agrobiodiversity resource offering considerable value as a buffer against crop failures, as a crop for niche markets, and as a source of diversity for crop genetic improvement activities underpinning future food security. Home gardens are reservoirs of landrace diversity, but some of the accessions held in them are vulnerable or threatened with extinction. Those associated with seed saving networks have added security, for example, ca. 800 varieties are stored in the Heritage Seed Library (HSL) of Garden Organic, UK. In this study, Amplified Fragment Length Polymorphisms-based genetic analysis of accessions held in the HSL was used to (a) demonstrate the range of diversity in the collection, (b) characterize accessions to aid collection management and (c) promote broader use of the collection. In total, 171 accessions were included from six crops: Vicia faba L. , Pisum sativum L. , Daucus carota L. , Cucumis sativus L. , Lactuca sativa L. and Brassica oleracea L. var. acephala (DC.) Metzq. Average expected heterozygosity ranged from 0.18 to 0.28 in D. carota; 0.02–0.18 in P. sativum; 0.05–0.18 in L. sativa; 0.15–0.26 in B. oleracea var. acephala; 0.15–0.37 in C. sativus and 0.07–0.36 in V. faba. Genetic diversity and Fst values generally reflected the breeding system and cultivation history of the different crops. Comparisons of the diversity found in heritage varieties with that found in commercial varieties did not show a consistent pattern. Principal coordinates analysis and Unweighted Pair Group Method with Arithmetic Mean cluster analysis were used to identify four potential duplicate accession pairs.
Aboveground Biomass Allocation and Additive Allometric Models for Natural Larix gmelinii in the Western Daxing’anling Mountains, Northeastern China

Accurate estimates of tree component and aboveground biomass strongly depend on robust and precise allometric equations. However, site-specific and suitable biomass equations are currently scarce for natural Larix gmelinii forests in the western Daxing’anling Mountains, northeastern China. This study aimed to evaluate the biomass allocation patterns within tree components and develop additive allometric biomass equations for species of L. gmelinii. A total of 58 trees were destructively sampled and measured for wood (inside bark), bark, branch and leaf biomass. For each component, we assessed the share of biomass allocated to different components by computing its ratio; we also tested two allometric equations based on diameter at breast height (dbh) alone, and dbh fitted with height (h) as independent variables. Seemingly unrelated regression methodology was used to fit an additive system of biomass allometric equations. We performed an independent dataset to evaluate the predictive ability of the best model system. The results revealed that wood biomass accounted for approximately 60% of the aboveground biomass. Wood and branch biomass ratios increased with increasing dbh, while a reverse trend was observed for bark and leaf biomass ratios. All models showed good fitting results with Adj.R2 = 0.958–0.995. Tree dbh provided the lowest estimation errors in the regressions associated with branches and leaves, while dbh2 × h generated the most precise models for stems (wood and bark). We conclude that these allometric equations will accurately predict biomass for Larix trees in the western Daxing’anling Mountains.
Examining the Popularity Concept in the Initial Public Offering (IPO) Market

2 POPULARITY. 5 Overview . 5 Classical Finance . 7 Capital Asset Pricing Model (CAPM) . 9 Fama-French Three-Factor Model . 12 Net Equilibrium Theory (NET) . 15 Behavioral Finance Overview . 18 Popularity Asset Pricing Model (PAPM) . 21 Conclusion . 29 INITIAL PUBLIC OFFERINGS (IPO) . 30 Overview . 30 Short-Term Underpricing Phenomenon . 31 Long-Term Overpricing Phenomenon . 34 Hot Issue Markets . 36 Conclusion . 38 EXAMINING POPULARITY IN THE IPO MARKET . 39 Overview . 39 Limitations. 40 Methodology . 41 CASE STUDIES. 43 #1 – Amazon.com (AMZN) . 43 #2 – eBay Inc. (EBAY) . 46 #3 – United Parcel Service (UPS) . 49 #4 – Stamps.com (STMP) . 52 #5 – Netflix Inc. (NFLX) . 55 #6 – Axis Capital Holdings LTD (AXS) . 58 #7 – Google Inc. now Alphabet Inc. (GOOGL) . 61 #8 – Domino’s Pizza Inc. (DPZ) . 63 #9 – Facebook Inc. (FB) . 65 #10 – Twitter Inc. (TWTR) . 67 #11 – Shake Shack Inc. (SHAK) . 69
Characterization of speciated atmospheric mercury concentration measurements in northern Utah

Two years of speciated atmospheric mercury data in the Intermountain West are examined for annual, seasonal, and diurnal patterns, as well as influences of precipitation. Mercury is a pollutant in the atmosphere that occurs as three species: gaseous elemental mercury (GEM), particulate-bound mercury (PBM), and gaseous oxidized mercury (GOM). Mercury can enter ecosystems from the atmosphere via wet and dry deposition. In aquatic ecosystems, it can convert to the neurotoxin methylmercury, which has prompted consumption advisories for both fish and waterfowl. A Tekran ambient air mercury monitor was deployed at a site (UT96) near the Great Salt Lake, Utah as part of the Atmospheric Mercury Network (AMNet). UT96 has the only such detector in continuous operation in Utah with two years of data (July 2009 June 2011). All three mercury species exhibit right-skewed distributions and vary in concentration over multiple orders of magnitude. GEM is the dominant species with a median concentration of 1.58 ng m−3 (range 0.25 64.47 ng m−3). PBM has a median concentration of 5.7 pg m−3 (range 0 803.2 pg m−3), while GOM has a median concentration of 2.6 pg m−3 (range 0 225.6 pg m−3). The sporadic nature of the extremely high GEM and PBM events suggest that they primarily result from local/regional emissions. In contrast, extremely high GOM events depend strongly on time of day and season, suggesting a connection to meteorological conditions. All three species exhibit statistically significant seasonal and diurnal patterns. GOM exhibits the strongest seasonal pattern, peaking during summer with median summer concentrations a factor of six greater than median winter concentrations. GEM and PBM peak during winter. All three species exhibit statistically significant diurnal patterns for at least part of the year. GOM has the most pronounced diurnal cycle, particularly during summer. Median concentrations of GOM during the afternoons of summer months are greater than 20 pg m−3, while median concentrations overnight are below 5 pg m−3. GEM and PBM both exhibit minima in concentrations during the afternoons, and both exhibit the largest diurnal variation amplitude during summer. Neither GEM nor PBM exhibit a statistically significant diurnal pattern during winter. An examination of the influences of precipitation on mercury concentrations indicates that precipitation scavenges GOM more efficiently than PBM, and that the scavenging increases as the amount of precipitation increases. Mixed precipitation scavenges PBM better than either rain or snow alone. The median GOM concentration during rain, snow, and mixed precipitation were all below the method detection limit (MDL), and could not be distinguished. There are some indications in the data that rain may promote slightly elevated concentrations of GEM.
Organic and inorganic fertilizer amendments on sustainable health of garden pea (Pisum sativum L.)

The study aims at assessing the effects of biofertilizer consortium and its integration with organic and chemical fertilizers on growth, yield and quality of garden pea on long term basis without any deleterious effect on natural resource base. The common pea (also known as the garden pea or field pea), is a herbaceous annual in the Fabaceae (formerly Leguminoseae) family. It is a legume known universally to fix atmospheric nitrogen with symbiotic activity of Rhizobium leguminosarum. The national yield of pea stands at 9.5 t/ha against the backdrop of Assam’s average productivity of 4 t/ha (Anonymous, 2014).
A Hybrid BCI Using Singular Value Decomposition Values of the Fast Walsh–Hadamard Transform Coefficients

One of the main goals of a brain computer interface (BCI) is to enable a communication channel between the brain and electronic devices by converting neural activity into control commands either for devices or applications. Because of the excellent temporal resolution, low set-up cost, and noninvasive nature, BCI systems generally use electroencephalography (EEG) for an input signal. However, EEG suffers from poor spatial resolution, and it is contaminated by various external and internal artifacts, such as environmental magnetic noises and body movements. These limitations directly affect the performance of the EEG-based BCI system, and it might not work at the desired level. On the other hand, near-infrared spectroscopy (NIRS) has an advantage of relative robustness against body movements and electrical artifacts. Additionally, it is also a promising neural signal recording method which provides good spatial resolution. In this study, we particularly focused on compensating the limitations of EEG-based BCI system by adding simultaneous NIRS modality features. In order to show the effectiveness of our method, we used an open-access data set, which was recorded from 29 subjects with simultaneous EEG-NIRS system during the imagination of opening and closing either a left- or right-hand. The features were extracted by calculating the singular value decomposition values of the Fast Walsh–Hadamard transform coefficients. Afterward, the ${k}$ -nearest neighbor algorithm was performed to classify the features. The performance of the proposed method was evaluated in terms of classification accuracy and kappa value metrics. The achieved results showed that combining a hybrid BCI system with EEG-NIRS modalities can enhance the performance of a BCI by 6.75% compared to the single-modality solution of EEG.