Miracle-dz/UniFAR-FTUs huggingface dataset:
Exposure to Aqueous-Alcoholic Extract of Parsley Leaves (Petroselinum crispum) in Lead-Treated Rats Alleviate Liver Damage

Lead (Pb) poisoning and the induced potential of the lesion is a global concern with harmful effects on multiple body systems, particularly the liver system. In this study, we have investigated the efficacy of aqueous-alcoholic extract of parsley leaves (PAE), which is a component of flavonoids that could play an important role in the antioxidant property, in preventing liver Pb-damages. For this, sixty adult male rats were randomly divided into six groups in a factorial arrangement: control; receiving oral gavage for 21 days with 2 mL water; 500 ppm Pb; 100 and 200 mg/kg PAE in combination form with Pb, and 200 mg/kg PAE. Liver enzymes and oxidative stress indexes were computed for liver stress, in blood serum. Apoptosis levels were assessed in the evaluation of liver gene expression. Data indicated that Pb reduced liver weight and feed intake. The results showed that Pb significantly increased the liver enzymes contents in the blood serum in the comparison vehicle group. Furthermore, the MDA contents of the Pb group rats were significantly more than that of the vehicle group. Likewise, T-AOC and the activities of CAT and SOD were significantly reduced. Meanwhile, Pb administration induced liver apoptosis-related genes by upregulating Bax and TNF-α genes and downregulating the Bcl-2 gene of animals. At the same time, administration of PAE significantly improved liver oxidative and apoptosis changes. Thus, this study provides a novel mechanistic approach concerning Pb-induced toxicity, due to PAE antioxidant activity.
EFFECTIVENESS OF INSTRUCTIONAL PROGRAM ON BREAST FEEDING TECHNIQUES FOR PRIM GRAVID WOMEN WHO RETURN THE PRIMARY HEALTH CARE CENTER IN AL-NAJAF CITY

Background: Breastfeeding support from the health care professionals can be effective in influencing a mother's decision to initiate and maintain breastfeeding. However, mothers do not always receive adequate breastfeeding education. Methodology: Quasi-experimental design is used to investigate the effectiveness of an instructional program among prim gravid women. Non probability ((purposive sample)) of 60 prim gravid women's participate in this study . they are divided into two groups: 30 women as study group are exposed to the instructional program, and other 30 prim gravid women are not exposed to the instructional program considered as control group. The study starting on 25th of December 2020 12th of June, 2021. Results: The results of this study indicating an increase in the level of post-test knowledge assessment about breastfeeding techniques and post feeding techniques of the study group after receiving the instructional program was mean of the score (ranged: 0.73-1.00), which rests on pass levels. Conclusions: The study reveals that the instructional program has positive effect on the study sample on the knowledge and practices of prim gravid women about breastfeeding techniques. Keywards: Effectiveness, Instructional Program, Breastfeeding, prim gravid women.
An innovative design concept for improving the durability of concrete bridges

It is proposed to build concrete bridges with tendons fully encapsulated in plastic ducts and without the use of reinforcing steel. In this case the durability of the proposed bridge depends only on the durability of the concrete because corrosion is no longer a determining factor regarding the lifetime of the structure. The requirements of the serviceability and ultimate limit states are fulfilled by providing post‐tensioned tendons with strands fully encapsulated in plastic ducts and watertight anchorages. Since the proposed bridge does not contain any steel, which would be endangered by material‐related corrosion, there is no need for insulation to the deck. Consequently, there is also no need for pavement and edge beams. This concept of building bridges represents a breakthrough with regard to sustainability and durability of concrete bridges and is applicable to small and mediumsized bridges. The method has already been implemented for the design of the Egg‐Graben Bridge in the Großarl valley in the province of Salzburg, Austria. Prior to the actual construction of the bridge, large‐scale tests were performed to obtain practical values for the serviceability, ductility and loadbearing capacity of this structural system.
Luteolin suppresses tumor proliferation through inducing apoptosis and autophagy via MAPK activation in glioma

Purpose Glioma is a malignant tumor that originates in the brain and spine and is difficult to be completely removed. Though glioma patients receive active treatment, the survival rate is still poor. Therefore, it is urgent to discover a new medicine to treat glioma patients in order to improve the survival rate. In this study, we explored the anticancer effect and the potential mechanism of luteolin on glioma in vitro. Materials and methods Cell viability was determined by Cell Counting Kit-8 (CCK-8) assay. Fluorescent microscopy and flow cytometry analysis were used to determine the cellular apoptosis. Western blot analysis was performed to explore the changes in protein expression. Quantitative reverse transcription-PCR (qRT-PCR) analysis was utilized to evaluate the expression level of the tumor suppressor miR-124-3p. Results CCK-8 assays indicated that luteolin significantly inhibited glioma cell proliferation in a time- and dose-dependent manner. Fluorescent microscopy and flow cytometry analysis confirmed that luteolin induced glioma cell apoptosis. Western blot analysis showed that luteolin induced cellular apoptosis in glioma cells via MAPK activation (JNK, ERK, and p38). Luteolin stimulated the death receptor (FADD) to regulate the apoptosis proteins (Caspase-8, Caspase-3, and PARP). Luteolin increased the expression levels of LC3B II/I and downregulated the level of p62 that promotes cell autophagy. Finally, qRT-PCR confirmed that luteolin upregulated the expression levels of miR-124-3p. Conclusion These findings illustrate that luteolin may be a potential drug for glioma treatment.
Information systems in support of employee empowerment: A study of manufacturing organisations in the UK.

This thesis investigates the role of computer-based information systems in manufacturing organisations that are encouraging employee empowerment. The central proposition of the research is that information systems are not able to empower employees, but they can support the new work practices created by empowerment, depending on the specific organisational circumstances. A postal survey addressing the top 450 manufacturing organisations in the UK is reported, which reveals the extent and characteristics of empowerment adoption and the main issues arising from the use of IS in this context. These were elaborated in a series of 20 in-depth interviews in selected organisations. While the data from the interviews highlighted the support that IS provide to employees and uncovered some problematic aspects, the further, more detailed study of two large manufacturing organisations enabled a better understanding of the nature of these difficulties. A conceptual framework based on structuration theory was employed for data analysis. The case studies reported suggest that the interaction between information systems and employees is in many cases problematic, because it continually reproduces the deeper structural properties of the organisation that essentially constrain empowerment. Although the encouragement of empowerment has affected some organisational practices, traditional institutionalised features largely persist. These not only inform the design and development of existing IS, but are continually reproduced through their use and management. However, this research revealed some instances where the interaction between human agents and IS did not reproduce, but rather transformed elements of structural properties. An analysis of these situations provided improved insights into the impact of IS on organisational structure, and their role in both the reproduction and transformation of structural properties. Our findings suggest that information systems cannot only support employees in their work practices at the level of action, but that they can also trigger a change in the structural properties of their organisation, thus contributing to empowerment. Critical to this transformation, which can be either intended or unintended, is the interplay between various groups of organisational actors and their motivations and interests for change. An improved perspective on the role of IS in unintended transformations of structure is put forward and to conclude, some implications of the research for both IS theory and IS practice are elicited.
Correlation Filtering of Modal Dynamics using the Laplace Wavelet

Wavelet analysis allows processing of transient response data commonly encountered in vibration health monitoring tasks such as aircraft flutter testing. The Laplace wavelet is formulated as an impulse response of a single mode system to be similar to data features commonly encountered in these health monitoring tasks. A correlation filtering approach is introduced using the Laplace wavelet to decompose a signal into impulse responses of single mode subsystems. Applications using responses from flutter testing of aeroelastic systems demonstrate modal parameters and stability estimates can be estimated by correlation filtering free decay data with a set of Laplace wavelets.
Le rôle des archées dans l'inflammation et leur impact sur la santé humaine

V TABLE DES MATIÈRES . VII LISTE DES TABLEAUX . XI LISTE DES FIGURES . XIII LISTE DES ABRÉVIATIONS ET DES SIGLES . XVII REMERCIEMENTS . XXI AVANT-PROPOS . XXIII 1. CHAPITRE
Knowledge Management and Organizational Design

From the Publisher: The collection draws on fifty years of management thinking and presents key issues facing knowledge-intensive organizations. The selections are concise, clearly written and present a rich framework of examples drawn from real management experience. Arranged thematically, the chapters discuss decision-making, organization structure, innovation, strategic alliances, managing knowledge workers and power relations. Represented in this volume are the ideas of influential academics including the late economist Frederick Hayek and French sociologist Michael Crozier, as well as world-renowned management thinkers such as Harvard Business School Professor Rosabeth Moss Kanter and Charles Handy.
Echocardiographic Heart Changes in Pregnancies Complicated with Gestation Hypertension and Preeclampsia

Introduction: Echocardiography as an imaging method is increasingly being used in obstetrics in the management of hemodynamic changes which occur in normal but also in pregnancies with gestational hypertension/preeclampsia. Aim: The aim of the study is to show that some of the heart changes in pregnancies complicated with gestational hypertension and preeclampsia are abnormal and further follow up of these patients is needed. Methods: A total of 81 patients were enrolled in the study. The patients were further divided in two groups. Pregnant women with gestational hypertension or preeclampsia (51) and a control group of normotensive pregnancies (30). A total of 3 echocardiograph exam were made, the first upon entry in the study (28 -34 g.w), the second 2 weeks after delivery and the last 6 months after delivery. Results and discussion: We found several statistically significant results that involve the IVS, PWLV, LKM, left chamber hypertrophy and diastolic function. Diastolic dysfunction usually shows up before systolic dysfunction in the evolution of ischemic/hypertensive cardiovascular disease and is of prognostic value in predicting long term cardiovascular morbidity. The changes seen 6 months after delivery on our last control mean that those changes are permanent and need further prevention strategies. Conclusion: From the noninvasive methods echocardiography is the most favorable method in identifying structural changes and functional changes in pregnancies with hypertension. Echocardiography allows fast, reproducible information and is both safe for mother and fetus.
Direction of gait asymmetry following stroke determines acute response to locomotor task

Background Given the prevalence of gait dysfunction following stroke, walking recovery is a primary goal of rehabilitation. However, current gait rehabilitation approaches fail to demonstrate consistent benefits. Furthermore, asymmetry is a prominent feature of gait dysfunction following stroke. Differential patterns of gait asymmetry may respond differently to gait training parameters. Objective The purpose of this study was to determine whether differential responses to locomotor task condition occur on the basis of direction of step length asymmetry (Symmetrical, NPshort, Pshort) observed during overground walking. Methods Participants first walked overground at their self-selected walking speed. Overground data were compared against three task conditions all tested during treadmill walking: self-selected speed with 0% body weight support (TM); self-selected speed with 30% body weight support (BWS); and fastest comfortable speed with 30% body weight support and nonparetic leg guidance (GuidanceNP). Our primary outcomes were: step length, single limb support duration, and stride length. Results We identified differences in the response to locomotor task conditions for each step length asymmetry subgroup. GuidanceNP induced an acute spatial symmetry only in the NPshort group and temporal symmetry in the Symmetrical group. Conclusions Task conditions consistent with locomotor training do not produce uniform effects across subpatterns of gait asymmetry. We identified differential responses to locomotor task conditions between groups with distinct asymmetry patterns, suggesting these subgroups may require unique intervention strategies. Despite group differences in asymmetry characteristics, improvements in symmetry noted in the Symmetrical and NPshort groups were driven by changes in both the paretic and nonparetic limbs.
COMPARATIVE GENOMICS ANALYSIS OF GROWTH HORMONE (GH), INSULIN-LIKE GROWTH FACTOR 1 (IGF-1) AND MYOSTATIN (MSTN) GENE SEQUENCES IN CHICKEN, RABBIT AND SHEEP

A THESIS SUBMITTED TO THE SCHOOL OF POSTGRADUATE STUDIES, AHMADU BELLO UNIVERSITY ZARIA IN PARTIAL FULFILLMENT OF THE REQUIREMENTS FOR THE AWARD OF MASTER OF SCIENCE DEGREE IN ANIMAL SCIENCE DEPARTMENT OF ANIMAL SCIENCE, FACULTY OF AGRICULTURE AHMADU BELLO UNIVERSITY, ZARIA, NIGERIA
Construction and Testing of GFRP Steel Hybrid-Reinforced Concrete Bridge-Deck Slabs of Sainte-Catherine Overpass Bridges

AbstractHybrid reinforcement for concrete bridge-deck slabs is being investigated through a collaboration project between the Ministry of Transportation of Quebec (MTQ) and the University of Sherbrooke. This paper presents design concepts, construction details, and results of live-load field tests of the twin hybrid-reinforced bridges (P-15502N and P-15502S) on Sainte Catherine Road in Sherbrooke, Quebec (Canada). These hybrid-reinforced slab-on-girder bridges are simply supported over a single span of 43,415 mm. Their 200-mm-thick concrete deck slabs are continuous over four spans of 2,650 mm each, with an average overhang of about 1,000 mm on both sides (measured perpendicular to the girder axis). The deck slabs were reinforced with glass fiber–reinforced polymer (GFRP) reinforcing bars in the top mat and with galvanized steel bars in the bottom mat. One of the two bridges (P-15502S) was instrumented with fiber-optic sensors (FOSs) in the bridge-deck slab (over and between the girders). The instrumented.
Innovator'S Dilemma

The innovator's dilemma explores the reasons why incumbent companies fail in the face of certain types of market and/or technological change. They fail because they listen to their customers, and focus of investing in sustaining technologies. However, this leaves them unable to cope with rise of disruptive technologies. Keywords: disruptive innovation; disruptive technologies; sustaining technologies; technological change; process technology
Accuracy of intraocular lens power calculation formulas in a steep cornea: A case report

There is no enough knowledge about the accuracy of intraocular lens (IOL) power calculation formulas in steep corneas. This study may be the first one that compares the accuracy of the SRK II formula with Holladay1, Hoffer Q and Haigis formulas in steep corneas. We reported a case of a 60-year-old female, with a cataract in the left eye and with a steep cornea. We used the modern formulas; Holladay1, Hoffer Q and Haigis. The result (+7.0D) was unexpected compared to the manifest refraction and to the IOL power calculated in the right eye using the same formulas which was (+17.0D). We implanted (+12.0D) Sensar 1-piece IOL depending on our clinical experience. The post-operative refraction was (+0.00/-1.75axis106). Postoperative, we used the patient data to find the best formula in this case. We found that the SRK II (A118) result was (+11.5D) and thus this formula was the most accurate in this case. Keywords: SRK II; Holladay1; Hoffer Q; Haigis
Au fait law placements

Purpose – Enhancing student employability and bridging the gap between theory and practice in law education requires a more multifaceted approach than the traditional mix of lectures, tutorials and simulations. Law placements also provide an opportunity to reinforce the importance of the professional practice standards and requirements laid down by the Law Society of Scotland. The purpose of this paper is to analyse the design and implementation of law placements from the point of initiation to becoming a regular practice. The emphasis is on placements embedded in the programme of study offered to Stage 3 students to facilitate their career choices prior to specialisation in the final year. Design/methodology/approach – This study utilises a longitudinal multi-method approach, allowing the analysis of various aspects the development and practical implementation of law-related placements. The views of students, academic staff and representatives of local employers are gathered by in-depth interviews. A ref.
Critical failure factors of Lean Six Sigma: a systematic literature review

Purpose – Lean Six Sigma (LSS) is a continuous improvement methodology that aims to reduce the costs of poor quality, improve the bottom-line results and create value for both customers and shareholders. The purpose of this paper is to explore the critical failure factors for LSS in different sectors, such as manufacturing, services, higher education, etc. Design/methodology/approach – The following research is based on a systematic literature review of 56 papers that were published on Lean, Six Sigma and LSS in well-known academic databases from 1995 to 2013. Findings – There are 34 common failure factors of LSS cited in this paper. There are some common factors for failure, such as a lack of top management commitment and involvement, lack of communication, lack of training and education, limited resources and others. Many gaps and limitations are discussed in this paper and need to be explored in future research. Originality/value – The paper is one of the first systematic literature reviews to explore .
Thru-the-wall Eavesdropping on Loudspeakers via RFID by Capturing Sub-mm Level Vibration

The unprecedented success of speech recognition methods has stimulated the wide usage of intelligent audio systems, which provides new attack opportunities for stealing the user privacy through eavesdropping on the loudspeakers. Effective eavesdropping methods employ a high-speed camera, relying on LOS to measure object vibrations, or utilize WiFi MIMO antenna array, requiring to eavesdrop in quiet environments. In this paper, we explore the possibility of eavesdropping on the loudspeaker based on COTS RFID tags, which are prevalently deployed in many corners of our daily lives. We propose Tag-Bug that focuses on the human voice with complex frequency bands and performs the thru-the-wall eavesdropping on the loudspeaker by capturing sub-mm level vibration. Tag-Bug extracts sound characteristics through two means: (1) Vibration effect, where a tag directly vibrates caused by sounds; (2) Reflection effect, where a tag does not vibrate but senses the reflection signals from nearby vibrating objects. To amplify the influence of vibration signals, we design a new signal feature referred as Modulated Signal Difference (MSD) to reconstruct the sound from RF-signals. To improve the quality of the reconstructed sound for human voice recognition, we apply a Conditional Generative Adversarial Network (CGAN) to recover the full-frequency band from the partial-frequency band of the reconstructed sound. Extensive experiments on the USRP platform show that Tag-Bug can successfully capture the monotone sound when the loudness is larger than 60dB. Tag-Bug can efficiently recognize the numbers of human voice with 95.3%, 85.3% and 87.5% precision in the free-space eavesdropping, thru-the-brick-wall eavesdropping and thru-the-insulating-glass eavesdropping, respectively. Tag-Bug can also accurately recognize the letters with 87% precision in the free-space eavesdropping.
HRMO in the region Kennemerland: A descriptive analysis: Prevalence, diagnostics, costs, transmission and risk factors

Background This paper describes (1) the Highly Resistant Gram Negative Rod (HR-GNR) prevalence rate, (2) their genotypes, acquired resistance genes and (3) associated risk factors of HR-GNR colonization among the hospitalized population in the Dutch region Kennemerland. Methods Between 1 October 2013 and 31 March 2014, cross-sectional prevalence measurements were performed in three regional hospitals as part of each hospitals infection control program. Rectal swabs were analyzed at the Regional Public Health Laboratory Kennemerland by direct culturing. Genotypes and acquired resistance genes of positive isolates were determined using Whole Genome Sequencing with the MiSeq instrument (Illumina). Association between several independent variables and HR-GNR positivity was examined using logistic regression models. Results Out of 427 patients, 24 HR-GNR positive isolates were recovered from 22 patients, resulting in a regional HR-GNR colonization prevalence (95% CI) of 5.2% (3.6-7.9). Of these 22 positive patients, 15 were Extended Spectrum Beta-Lactamase (ESBL) positive (3.5% (2.15.7)), 7 patients were positive for a Fluoroquinolones and Aminoglycosides (Q&A) resistant Enterobacteriaceae (1.6% (0.8-3.3)) and from one patient (0.2% (0-1.3)) a Stenotrophomonas maltophilia resistant towards co-trimoxazole was isolated. No carbapenemase producing Enterobacteriaceae (CPE), multi-resistant Acinetobacter species or multi-resistant Pseudo­ monas aeruginosa were isolated. The ESBL genes found were blaCTX-M-1 (n = 4, 25.0%), bla­ CTX-M-15 (n = 3, 18.8%), blaCTX-M-27 (n = 2, 12.5%), blaCTX-M-14b (n = 2, 12.5%), blaCTX-M-9 (n = 2, 12.5%), blaCTX-M-14 (n = 1, 6.3%), blaCTX-M-3 (n = 1, 6.3%), blaSHV-11 (n = 1, 6.3%) and blaSHV-12 (n = 1, 6.3%). Being known HR-GNR positive in the past was the only significant associated risk factor for HR-GNR positivity, odds ratio (95%CI): 7.32 (1.82-29.35), p-value = 0.005. Conclusions Similar ESBL prevalence rates and genotypes (3.5%) were found in comparison to other Dutch studies. When previously HR-GNR positive patients are readmitted, they should be screened for HR-GNR colonization since colonization with GR-GNRs could be prolonged. We recommend for future studies to include all defined HR-GNRs in addition to ESBLs in prevalence studies, in order to obtain a more comprehensive overview of colonization with HR-GNRs. 21 Prevalence, risk factors and molecular epidemiology of HR-GNRs in hospitalized patients