Miracle-dz/UniFAR-FTUs huggingface dataset:
Two-mode giant optical non-linearity with a single quantum dot in a photonic waveguide

Controlling light by light at the single photon level is a fundamental quest in the field of quantum computing, quantum information science and classical ultra-low power optical computing. A quantum light emitter made of a single two-level system is a highly non-linear medium, where the interaction of one photon with the medium can modify the transmission of another incoming photon. In this scenario, the most challenging issue to obtain a giant optical non-linearity is to optimize photon-emitter interaction. This issue can be overcome by inserting the quantum emitter inside a photonic structure. This system is known as “one-dimensional atom”: the light collection efficiency as well as the probability for an emitter to absorb a photon fed into the structure is maximum. In this study, we aim at using such kind of system to experimentally realize a two-mode giant non-linearity, in which the reflection of one light mode is controlled by another light mode at the single-photon level. The system consists of a semiconductor InAs/GaAs quantum dot, which can be considered as an artificial atom, embedded inside a GaAs photonic wire, which is an optical waveguide. The photonic wire defines a single spatial mode around the emitter and offers a close to unity light-emitter interaction efficiency. In addition, the photonic wire also possesses a spectrally broadband operation range. Thanks to these two excellent features of the system, we experimentally demonstrate in this thesis a single-mode and a two-mode giant non-linearity obtained at the level of just a few tens of photons per emitter lifetime. This realizes an integrated ultra-low power all-optical switch.
It Takes a Village: Using Network Science to Identify the Effect of Individual Differences in Bilingual Experience for Theory of Mind

An increasing amount of research has examined the effects of bilingualism on performance in theory of mind (ToM) tasks. Bilinguals outperform monolinguals in ToM when comparing groups. However, it is unclear what aspects of the bilingual experience contribute to this effect in a dynamic construct like ToM. To date, bilingualism has been conceptualized as a dichotic skill that is distinct from monolingualism, obscuring nuances in the degree that different bilingual experience affects cognition. The current study used a combination of network science, cognitive, and linguistic behavioral measurements to explore the factors that influence perspective-taking ToM based on participants’ current and previous experience with language, as well as their family networks’ experience with language. The results suggest that some aspects of the bilingual experience predict task performance, but not others, and these predictors align with the two-system theory of ToM. Overall, the findings provide evidence for the extent to which individual differences in bilingualism are related to different cognitive outcomes.
Design of memory Alias Table based on the SRAM 8T‐Cell

A memory Alias Table holds a major role in Register Renaming Unit (RRU), which is responsible for maintaining the translation between logical registers to physical registers under the given instruction(s). This work presents the design of the memory Alias Table based on the SRAM‐based 8T‐Cell with multiport write, read, and content‐address operations for two‐way three operands machine cycle. The design of the memory Alias Table of size 32‐row × 6‐bit has SRAM‐based CAM cell of type 21T‐Cell that comprises four‐read ports, two‐write ports, and two‐content‐address ports. The content‐address examines the register under‐test against all contents of the memory Alias Table in parallel and releases the associated match index address. Results show that the four read ports operate simultaneously within the half‐cycle, while the two write ports operate simultaneously within the other half‐cycle. The operation of the two content‐address ports is managed during the half‐cycle of the read phase. Thus, the three operations occur within a single cycle without latency. HSPICE simulations using 90 nm/1 V CMOS process reveal that the memory Alias Table provides the three operations within a one‐cycle of 1 GHz consuming an average power of 0.13 mW.
Tongbixiao Pills Improve Gout by Reducing Uric Acid Levels and Inhibiting Inflammation

Gout is a chronic disease. Gout symptoms are often experienced in the middle of the night. The onset of gout in the middle of the night is closely related to abnormal liver and gallbladder meridian. The purpose of this study was to investigate the clinical efficacy and possible mechanism of action of Tongbixiao pills in the treatment of hyperuricemia and gouty arthritis. The Tongbixiao pills we used included several traditional Chinese medicines, most of which tonify the spleen; strengthen the liver; benefit the kidney; and reduce heat, dampness, and blood stasis. In this randomized clinical study of 105 patients, we found that Tongbixiao pills can reduce uric acid levels in hyperuricemia patients. Additionally, the efficacy was similar to that of allopurinol and the level of uric acid did not increase significantly at eight weeks after withdrawal. In the absence of notable adverse reactions, Tongbixiao pills can also increase uric acid excretion, reduce serum creatinine and lipid levels, and reduce inflammation and relieve gout symptoms. In addition, we used SD rats to simulate gout and arthritis and divided them into five groups: normal group, model group, low-dose group, medium-dose group, and high-dose group. The inflammatory indices of the 40 SD rats were observed. After seven days, ankle swelling in rats in the treatment group was significantly reduced. The indices of uric acid, creatinine, and urea nitrogen in the treatment group were significantly lower than those in the model group, which proved that Tongbixiao pills could inhibit hyperuricemia in rats, thus treating gout. This study demonstrates that Tongbixiao pills can treat gout, provide more treatment options for gouty arthritis, and improve the quality of life of patients.
Patient Activeness During Online Medical Consultation in China: Multilevel Analysis

Background Online medical consultation is an important complementary approach to offline health care services. It not only increases patients’ accessibility to medical care, but also encourages patients to actively participate in consultation, which can result in higher shared decision making, patient satisfaction, and treatment adherence. Objective This study aims to explore multilevel factors that influence patient activeness in online medical consultations. Methods A data set comprising 40,505 patients from 300 physicians in 10 specialties was included for multilevel analysis. Patient activeness score (PAS) was calculated based on the frequency and the proportion of patient discourses to the total frequency of doctor-patient interactions. Intraclass correlation coefficients were calculated to identify between-group variations, and the final multilevel regression model included patient- and physician-level factors. Results Patients were not equally active in online medical consultations, with PASs varying from 0 to 125.73. Patient characteristics, consultation behavioral attributes, and physician professional characteristics constitute 3 dimensions that are associated with patient activeness. Specifically, young and female patients participated more actively. Patients’ waiting times online (β=–.17; P<.001) for physician responses were negatively correlated with activeness, whereas patients’ initiation of conversation (β=.83; P<.001) and patient consultation cost (β=.52; P<.001) in online medical consultation were positively correlated. Physicians’ online consultation volumes (β=–.10; P=.01) were negatively associated with patient activeness, whereas physician online consultation fee (β=.03; P=.01) was positively associated. The interaction effects between patient- and physician-level factors were also identified. Conclusions Patient activeness in online medical consultation requires more scholarly attention. Patient activeness is likely to be enhanced by reducing patients’ waiting times and encouraging patients’ initiation of conversation in online medical consultation. The findings have practical implications for patient-centered care and the improvement of online medical consultation services.
Measuring the Impact of Greece as a Safe Branding Tourist Destination: Evidence from Spain and Greece

After the first wave of the COVID-19 outbreak, many tourist destinations promoted a safe, COVID-free image to attract tourists. The main purpose of this paper is to examine and analyze the effect that the image of a place as a safe tourist destination (STD)—in our case, Greece—can have on the decision-making processes of tourists who were willing to take summer holidays in 2020 amid the COVID-19 pandemic. We examined the relationships between destination safety perceptions, trust, attractive attributes of destinations, travel intentions, and health-protective behavior for domestic and inbound tourists from Spain. This study confirms differences in destination safety perceptions among domestic and inbound tourists from countries that have suffered significant negative impacts due to the novel coronavirus.
Efflux pump and its inhibitors: Cause and cure for multidrug resistance

Multidrug resistance has become a threat to global public health as a result of resistance of microbes toward several drugs leading to prolonged period of illness, disability, incapacity, and death. Such multidrug resistance is seen principally in organisms involved in nosocomial infections also called as hospital-acquired infections. Enterococcus species, Staphylococcus aureus , Klebsiella pneumoniae , Acinetobacter baumannii , Pseudomonas aeruginosa , and Enterobacter species (ESKAPE pathogens) are one of the major causes of nosocomial infections. Organisms acquire resistance to various antibiotics because of repetitive use and unprescribed medication. There are different mechanisms responsible for multidrug resistance, viz. inactivation by enzymes or alteration of drug, modification of drug binding site, reduction in intracellular drug accumulation, formation of biofilm, and preventing drug access to target (efflux pump). Among these the most common mechanism adopted by the organism is efflux pump and is profoundly seen in P. aeruginosa , Escherichia coli , and Candida albicans. An efflux pump is the channel that actively exports antimicrobials and other compounds out of the cell. Molecules involved in the inhibition of efflux mechanisms are known as efflux pump inhibitors. In this review, we mainly focus on the efflux pump as the major cause of escape of pathogens (mainly ESKAPE pathogens) from the action of antibiotics and strategies that can be used to overcome the resistance caused by these pumps.
Computed Tomography–Based Stiffness Measures of Trabecular Bone Microstructure: Cadaveric Validation and In Vivo Application

Osteoporosis causes bone fragility and elevates fracture risk. Applications of finite element (FE) analysis (FEA) for assessment of trabecular bone (Tb) microstructural strength at whole‐body computed tomography (CT) imaging are limited due to challenges with Tb microstructural segmentation. We present a nonlinear FEA method for distal tibia CT scans evading binary segmentation of Tb microstructure, while accounting for bone microstructural distribution. First, the tibial axis in a CT scan was aligned with the FE loading axis. FE cubic mesh elements were modeled using image voxels, and CT intensity values were calibrated to ash density defining mechanical properties at individual elements. For FEA of an upright volume of interest (VOI), the bottom surface was fixed, and a constant displacement was applied at each vertex on the top surface simulating different loading conditions. The method was implemented and optimized using the ANSYS software. CT‐derived computational modulus values were repeat scan reproducible (intraclass correlation coefficient [ICC] ≥ 0.97) and highly correlated (r ≥ 0.86) with the micro‐CT (μCT)‐derived values. FEA‐derived von Mises stresses over the segmented Tb microregion were significantly higher (p < 1 × 10−11) than that over the marrow space. In vivo results showed that both shear and compressive modulus for males were higher (p < 0.01) than for females. Effect sizes for different modulus measures between males and females were moderate‐to‐high (≥0.55) and reduced to small‐to‐negligible (<0.40) when adjusted for pure lean mass. Among body size and composition attributes, pure lean mass and height showed highest (r ∈ [0.45 0.56]) and lowest (r ∈ [0.25 0.39]) linear correlation, respectively, with FE‐derived modulus measures. In summary, CT‐based nonlinear FEA provides an effective surrogate measure of Tb microstructural stiffness, and the relaxation of binary segmentation will extend the scope for FEA in human studies using in vivo imaging at relatively low‐resolution. © 2022 The Authors. JBMR Plus published by Wiley Periodicals LLC on behalf of American Society for Bone and Mineral Research.
Pre-timed control for an under-saturated and over-saturated isolated intersection: a Bee Colony Optimization approach

ABSTRACT In this paper we study the problem of determining the optimum cycle and phase lengths for isolated signalized intersections. Calculation of the optimal cycle and green phase lengths is based on the minimization of the average control delay experienced by all vehicles that arrive at the intersection within a given time period. We consider under-saturated as well as over-saturated conditions at isolated intersections. The defined traffic signal timing problem, that belongs to the class of combinatorial optimization problems, is solved using the Bee Colony Optimization (BCO) metaheuristic approach. The BCO is a biologically inspired method that explores collective intelligence applied by honey bees during the nectar collecting process. The numerical experiments performed on some examples show that the proposed approach is competitive with other methods. The obtained results show that the proposed approach is capable of generating high-quality solutions within negligible processing times.
Performance monitoring by managerial teams

Purpose This paper aims to explore the design of management teams when the critical task facing individual managers is monitoring the performance of worker teams and producing performance measures under uncertain information environments. Design/methodology/approach The authors use a multi-agent LEN framework – linear contract, exponential utility and normal density – to model the incentive provision and organizational design. Findings The main lesson is that the use of performance measures under uncertainty is greatly affected by the potential for free-riding in the very monitoring activities which generate the measures to begin with. Accordingly, the value of having a management team, that is the incremental benefit of having a second manager, depends on the monitoring technology. Of particular importance are the potential free-riding in monitoring effort among multiple managers and synergies gained from having more than one manager, such as correlation among the performance measures produced or improvement due to splitting workers pool into separate groups for each manager to monitor separately. Originality/value The paper pushes this line of research further by explicitly modeling the endogenous process of signal generation within a rich economic environment. In this environment, number of workers being evaluated and number of managers who produce the signals are both endogenous. Furthermore, both workers and managers are subject to moral hazard problem. In particular, the managers suffer from potential free-riding problems but may benefit from synergistic forces due to team monitoring.
DO PARENTS INTRODUCE AGRICULTURAL LIVELIHOOD TOWARDS RURAL-YOUTH? Understanding Communication Pattern Between Parents and Rural-Youth related to Agricultural Livelihood in Ciasmara Village, Pamijahan Sub-district, Bogor Regency

The regeneration of agricultural workers has decreased in the last 10 years, this is feared to have an impact on food security in Indonesia. There are several things that cause the absence of young workers in agricultural sector, including how agricultural values are passed on to their children. This study will focus on (1) identifying communication frequency between parents and youth in context of agricultural work (2) identifying actors that communicate with rural youth in context of agricultural work. (3) Identifying the discussion topics between parents and rural youth in context of agricultural work. This research was carried out in Ciasmara Village, Bogor Regency from June 2020 - August 2021. Ciasmara Village was chosen as the research location because the village is one of the rice barns in Bogor Regency and the largest rice contributor to the capital city area. A total of 120 village youths were selected as research respondents through purposive sampling method. The results showed that parents still communicated about agriculture to their children in the context of rice cultivation and how to harvest rice. Both of these information are the most frequently discussed information because they are closely related to family labor to save production costs.
Characterization and Discrimination of Italian Olive (Olea europaea sativa) Cultivars by Production Area Using Different Analytical Methods Combined with Chemometric Analysis

Olives and olive products are particularly important for the national agroindustrial sector, for the aspects related to the production territory (authenticity), and for the link with the Mediterranean Diet. Several studies indicate that the elemental profile of olive and olive products depends on the production area in which the olive trees were grown, and the elemental content of the olives can be used as a marker of the production area. In order to confirm this hypothesis, the multi-elemental profile of olive drupes and olive leaves of eleven cultivars arising from two different production areas was evaluated through ICP-MS and ICP-AES techniques. In addition, some leaf samples were analysed by LPAS in order to evaluate the applicability of this new analytical technique for determining the geographic origin. The obtained results, combined with chemometric tools, showed the possibility of discriminating samples according to the production area on the basis of the elemental content, as well as by LPAS.
One Year of Experience Managing Peritonitis Secondary to Gastrointestinal Perforation at a Tertiary Care Hospital: A Retrospective Analysis

Introduction Peritonitis secondary to gastrointestinal perforation causes high morbidity and mortality rates in the emergency department with an immediate need for surgical intervention. Despite improved surgical management procedures, patients are still suffering from gastrointestinal leak causing peritonitis that demands surgical management by highly skilled surgeons in high-quality surgical units. Material and methods This paper presents one year of experience in the surgical treatment of gastrointestinal perforation-related peritonitis by surgeons in Lahore General Hospital, Lahore, Pakistan. Data was retrospectively collected from patient records and quantitatively analyzed. Involved patients developed peritonitis secondary to gastrointestinal perforation requiring surgical exploration and interventions in the emergency department between November 2020 and October 2021. Results One hundred and fifty-eight patients were involved; the mean age was 43.46 years. The number of males was 87 (55.06%). The patients mostly presented with generalized abdominal pain (57.6%). All the patients had perforation-related peritonitis, which was most prevalent in the ileum (62%). The most performed surgical intervention was loop ileostomy (36.71%). Compared to other published reports, the incidence rate of wound dehiscence in the hospital was relatively higher. Postoperatively, wound infection was low if the skin was left open (23.62%) compared to closed skin (38.7%). Patient outcomes were acceptable as the death rate was low (3.2%, 5/158). Conclusion Peritonitis caused by gastrointestinal perforation is associated with a high risk of morbidity that necessitates surgical exploration. Leaving skin wound open after the surgical intervention is recommended to decrease the incidence of wound infection and dehiscence.
An Exploration of Chaos in Electrical Circuits

This senior project investigates chaotic behavior and controlled chaos in electrical circuits. It primarily focuses on two types of circuits: one with a varicap diode and one with a operational ampliﬁer based Chua diode. These are the non-linear elements of the circuit that produce chaotic behavior in voltage outputs. Attempts to get the circuits to function correctly were unsuccessful, but the project includes a theoretical investigation of the chaotic behavior of the circuits through bifurcations and period doubling, as well as ways this behavior could be theoretically controlled.
Homogeneous and Stratified Liquid-Liquid Flow Effect of a Viscosity Reducer: I. Comparison in parallel plates for heavy crude

Production of heavy crude oil in Mexico, and worldwide, is increasing which has led to the application of different methods to reduce viscosity or to enhance transport through stratified flow to continue using the existing infrastructures. In this context, injecting a viscosity improver that does not mix completely with the crude, establishes a liquid-liquid stratified flow. On the basis of a parallel plates model, comparing the increase of flow that occurs in the one-phase case which assumes a complete mixture between the crude and the viscosity improver against another stratified liquid-liquid (no mixing between the oil and compared improver); it was found that in both cases there is a flow increase for the same pressure drop with a maximum for the case in which the flow improver is between the plates and the crude.
Processed meat consumption increases risk of type 2 diabetes mellitus in adults aged 40 years and older

Background Type 2 diabetes mellitus (T2DM) remains a public health problem in the world, including Indonesia. The high mortality of T2DM is triggered by an unhealthy eating pattern and sedentary lifestyle. We aimed to investigate the relationship of food intake pattern and its related factors with T2DM in adults 40 years and older. MethodsThis was a cross-sectional study conducted on 11,022 men and women with T2DM aged 40 years and older. Major dietary patterns were collected and multiple logistic regression analysis was used to determine the effect of covariates. Statistical significance was set at a p-value of <0.05. ResultsMales and individuals aged >40 years comprised 50.17% and 26.19%, respectively, of the 11,022 respondents. Individuals aged over 50 years had a higher risk of developing diabetes than those aged less than 50 years (AOR =5.67, 95% CI=1.37-21.94, p<0.05). Dietary processed meat was associated with a higher risk of T2DM (AOR = 4.9; 95% CI=1.08-22.20, p<0.05). Carbohydrate and fruit intakes were negatively associated with and protective factors for DM (AOR= 0.01; 95% CI=0.01-0.06, p<0.01; AOR = 0.35; 95% CI=0.15-0.83, p<0.01). However, physical activity was not a risk factor for T2DM. ConclusionsProcessed meat consumption, age over 50 years, and carbohydrate intake may increase the risk of T2DM in adults. Conversely, fruit intake may decrease the risk of T2DM in adults. There is a need to control the diet and lifestyle for the early prevention of DM.