Miracle-dz/UniFAR-FTUs huggingface dataset:
Identifying knowledge gaps for successful restorative aquaculture of Ostrea edulis: a bibliometric analysis

Background: Active restoration is necessary to enhance the recovery of Ostrea edulis reefs, which contribute to many ecosystem services. Restoration can be integrated within aquaculture practices, bringing positive environmental changes while maximising space utilisation. The restoration project MAREA (MAtchmaking Restoration Ecology and Aquaculture) aims to bring back O. edulis in the North-West Adriatic addressing the feasibility of its cultivation. Both successful restoration and sustainable aquaculture require a thorough understanding of the ecological needs, as the requirements of both activities need to be harmonized. Therefore, one of the preliminary activities before embarking on the pilot was the completion of a thorough literature review to identify research directions and gaps required for ‘restorative aquaculture’, aiming to gather the most up to date O . edulis knowledge on a global and local scale. Methods: Internet (Web of Science, Scopus, Google scholar) and physical resources (libraries) were searched for all available global and local knowledge on O . edulis. Bibliometrix was used to identify the main research topics using keywords, titles, and abstracts analyses. Studies were then manually screened and summarised to extract knowledge specific to restoration and aquaculture. Results: While restoration studies are recent, evidence for the loss of this species and potential causes (and solutions) have been discussed since the end of the 19 th century. While diseases were a leading cause for reef loss, substratum limitation appears to be one of the leading limiting factors for both restoration and aquaculture of O . edulis, and was already mentioned in the early texts that were found. Conclusions: The review highlighted that restoration success and aquaculture feasibility depend upon the crucial stage of settlement. The project ‘MAREA’ will therefore increase its focus on this stage, both in terms of timing, location, and materials for settlement plates placement.
Influence of breed on the quality of in vivo produced embryos from Boran and Holstein Friesian cross dairy breed in Ethiopia

The variation of the dairy breed can determine the success of bovine embryo transfer by influencing the quantity and quality of in vivo embryo production. In this experiment, output and quality of in vivo produced embryos using semen of progeny tested Holstein Friesian (HF) sire in Boran and HF*Boran F1 cross cows, and semen from purebred Boran sire in HF*Boran F1 cross and Boran cows were evaluated. Boran (n=18) and HF*Boran cross (n=18) breed donor dams were superovulated using a previously optimized follicular stimulating hormone (FSH) (Pluset®) dose regimen: 650 IU for HF*Boran cross and 250 IU for Boran breeds. Each cow was flushed on Day-7 post insemination and embryos were evaluated for their developmental stages and quality. Superovulatory response rates were 88.9% and 83.3%, respectively, for Boran and HF*Boran with no significant (P>0.05) breed differences. Total recovery rates were relatively lower (56.5%) in Boran compared to in HF*Boran (67.4%). The mean (±SE) embryo flush outputs were 6.5±0.8 for Boran and 6.9±0.7 forHF*Boran with no significant breed difference. Recovery of a transferrable embryo was significantly higher (68.0%; P<0.05) in HF*Boran dam inseminated with HF sire semen. Boran cows yielded a significantly higher (P<0.05) proportion of unfertilized ovum (57.6 %) irrespective of the sire breeds. Comparatively, a higher number of degenerated embryos were produced by HF*Boran cows. This study demonstrated that the presence of breed-related differences in both the quality and quantity of in vivo produced Bovine embryos.
Investigating antimicrobial features and drug interactions of sedoanalgesics in intensive care unit: an experimental study

Study Objective Aim of this study was to evaluate antimicrobial effects and interaction between analgesic combinations of fentanyl citrate, dexmedetomidine hydrochloride and tramadol hydrochloride on Staphylococcus aureus, Klebsiella pneumoniae, Escherichia coli, Pseudomonas aeruginosa and Candida albicans which are some of the most common nosocomial infection related microorganisms. Design In vitro prospective study. Setting University Clinical Microbiology Laboratory. Measurements In order to evaluate in vitro antimicrobial effects and interaction between analgesic combinations, tramadol hydrochloride, fentanyl citrate and dexmedetomidin were used against S. aureus ATCC 29213, K. pneumoniae, E. coli ATCC 25922, P. aeruginosa ATCC 27853 and C. albicans ATCC 10231 standard strains by microdilution method. Main Results According to microdilution assays tramadol has shown the most efficient antimicrobial activity also it has been observed that 10 μg/ml concentrated dexmedetomidine has antimicrobial effects on S. aureus, K. pneumoniae and P. aeruginosa. Fentanyl has displayed evident inhibitory potency on the pathogens except for Klebsiella pneumoniae, nevertheless our predefined minimum concentration inhibited growth by 9.5 %. Fentanyl and dexmedetomidine together exhibited more antimicrobial effect on P. aeruginosa and E. coli growth. Additionally, when the three drugs examined together, microbial inhibition occurred more than expected on E. coli again and also on C. albicans growth. Conclusions Our results revealed the antimicrobial properties and synergy with the different combinations of fentanyl, dexmedetomidine and tramadol against the most common nosocomial infection agents in the ICU. This is the first study in the literature looking into the microbial “interactions” of opioids and sedative drugs but more research is needed in order to define clinico-laboratory correlation.
Portfolio investment and U.S. monetary policy announcements: An event study analysis using high-frequency data from Mexico

We study how unconventional monetary policy announcements affected the entry of foreign investment in debt and equity in Mexico, placing special focus on announcements related to the third QE program and the taper tantrum episode. A novel dataset on daily debt and equity flows, that maps Balance of Payments data quite well, allows this paper to provide a better insight into movements of capital. The results suggest that both equity and debt flows reacted immediately to unexpected U.S. monetary policy announcements, particularly if these are considered as bad news by investors. In turn, results using weekly data support the idea that investors interested in fixed income instruments move more prudently than those interested in equity which react quickly.
CEO CHARACTERISTICS AND EARNINGS MANAGEMENT: EVIDENCE FROM INDONESIA

The CEO has an important role as a decision maker in the company and is responsible for the company's performance. This study was conducted to measure the effect of CEO on earnings management in 495 samples of non-financial companies listed on the Indonesia Stock Exchange in 2017-2019 using panel regression analysis with classical assumption testing. The results of panel regression examiners show that there is no significant effect between female CEOs and CEO turnover on earnings management proxies with discretionary accruals. Meanwhile, CEO tenure and company size show a significant negative relationship with earnings management. On the other hand, leverage and return on assets have a significant positive effect on earnings management. In addition, there is no significant influence between company age and Market to Book ratio on earnings management.
OTT_A_322697 4761..4777

1Department of Thoracic Surgery, Saitama Medical Center, Jichi Medical University, Saitama, Japan; 2Department of Medicine, Saitama Medical Center, Jichi Medical University, Saitama, Japan; 3Department of Pathology, School of Medicine, International University of Health and Welfare, Tochigi, Japan; 4Division of Pulmonary Medicine, Department of Medicine, Jichi Medical University, Tochigi, Japan; 5Department of Breast and Endocrine Surgery, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan; 6Division of Breast Surgery, Hospital of the National Center for the Global Health and Medicine, Tokyo, Japan; 7Department of Gastrointestinal Surgery, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan; 8Department of Molecular and Cellular Pathology, Graduate School of Medical Sciences, Kanazawa University, Kanazawa, Japan; 9Tokushima University IndustryUniversity R&D Startup Leading Institute, Tokushima, Japan Introduction: Trefoil Factor (TFF) is a member of a protein family comprised of three isoforms, of which TFF-1 exhibits antithetical functions; promotion or suppression of cell proliferation, survival and invasion, depending on the cancer type. However, the pathobiological function of TFF-1 in lung carcinoma has been still unclear. Methods: We examined the expression and secretion of TFF-1 using cultured human lung carcinoma cells by immunoblotting, immunofluorescence, enzyme-linked immunosorbent assay and quantitative real-time PCR analyses. The effects of TFF-1 on various phenotypes were analyzed in two cell lines, including those transfected with cDNA encoding TFF-1. Cell proliferation and death were examined by hemocytometer cell counting and by colorimetric viability/cytotoxicity assay. Cell cycle profile, migration and invasion were also examined by flow cytometry, wound healing assay and Matrigel Transwell assay, respectively. The effect of TFF-1 overexpression was confirmed by additional transfection of TFF-1-specific siRNA. Results: Endogenous TFF-1 protein expression and secretion into the media were observed exclusively in adenocarcinoma-derived cell lines. Forced overexpression of TFF-1 drove cell cycle transition, while the proliferation decreased by 19% to 25% due to increased cell death. This cell death was predominantly caused by apoptosis, as assessed by the activation of caspase 3/7. Cell migration was also suppressed by 71% to 82% in TFF-1-transfected cells. The suppressive effect of TFF-1 on proliferation and migration was restored by transfection of TFF-1 siRNA. Moreover, invasion was also suppressed to 77% to 83% in TFF-1-transfected cells. Conclusion: These findings reveal that TFF-1 functions as a suppressor of cancer proliferation by induction of apoptosis, cell migration and invasion and thus may provide a synergistic target for potential treatment strategies for human lung carcinoma.
Development and validation of a novel pre-operative comprehensive prognostic score in esophageal squamous cell carcinoma

We herein propose a novel integrative score based on inflammatory and nutritional score, coagulation indicator and tumor marker, named comprehensive prognostic score (CPS), to predict post-operative survival in resectable esophageal squamous cell carcinoma (ESCC). We also aimed to establish and validate a nomogram based on CPS and other clinical features for individual survival prediction. A total of 490 resectable ESCC patients were randomly divided into either a training or validation cohort at a ratio of 7:3 for retrospective analysis. The CPS, based on squamous cell carcinoma antigen, C-reactive protein to albumin ratio, neutrophil to lymphocyte ratio, and fibrinogen, was divided into two models to verify its prognostic value. The predictive model of CPS-based nomogram was established and validated in two cohorts. The patients with CPS low group in Model 1 had better 5-year cancer-specific survival (CSS) than those in CPS high group (50.7% vs. 17.8%, p < 0.001). For Model 2, the 5-year CSS for CPS 0, 1 and 2 were 75.0%, 38.9% and 13.3%, respectively (p < 0.001). CPS was confirmed as an independent prognostic score in both models. The CPS-based nomogram can accurately and effectively predict survival in resected ESCC. The CPS is a novel, simple, and effective predictor in resectable ESCC. Moreover, CPS has a potential independent prognostic value in predicting post-operative survival, which can accurately and effectively predict individual survival in resectable ESCC.
Agile Software Development Techniques: A Survey

In this IT era, where there is a race of software development, it is necessary to introduce such types of software development techniques which will help the practitioners to deliver fast solutions. In the past, various traditional approaches were used for this purpose, but now agile techniques are getting more popular because conventional software development approaches are not efficient in managing the changing requirements. The agile software development process is one of the most emerging lightweight software development methodologies, which uses iterative and prototype development approaches to accommodate changes in software requirements. Final software products are delivered to the end-users in short iterations. One of the most noticeable drawbacks of agile methods is their limited courtesy to the structured and architectural design of the system. Hence this development approach will restrict small to medium design decisions only. In this paper, we have performed the analysis of different agile techniques, which will help the readers to understand their positive and negative points and select the most appropriate technique suited to their projects.
A temperature-dependent mechanical model to assess the stability of degrading permafrost rock slopes

Abstract. Over the last 2 decades, permafrost degradation has been observed to be a major driver of enhanced rock slope instability and associated hazards in high mountains. While the thermal regime of permafrost degradation in high mountains has been addressed in several modelling approaches, no mechanical models that thoroughly explain rock slope destabilisation controls in degrading permafrost have been developed. Meanwhile, recent laboratory studies have shown that degrading permafrost affects both, rock and ice mechanical strength parameters as well as the strength of rock–ice interfaces. This study presents a first general approach for a temperature-dependent numerical stability model that simulates the mechanical response of a warming and thawing permafrost rock slope. The proposed procedure is exemplified using a rockslide at the permafrost-affected Zugspitze summit crest. Laboratory tests on frozen and unfrozen rock joint and intact rock properties provide material parameters for discontinuum models developed with the Universal Distinct Element Code (UDEC). Geophysical and geotechnical field surveys reveal information on permafrost distribution and the fracture network. This model can demonstrate how warming decreases rock slope stability to a critical level and why thawing initiates failure. A generalised sensitivity analysis of the model with a simplified geometry and warming trajectory below 0 ∘C shows that progressive warming close to the melting point initiates instability above a critical slope angle of 50–62∘, depending on the orientation of the fracture network. The increase in displacements intensifies for warming steps closer to 0 ∘C. The simplified and generalised model can be applied to permafrost rock slopes (i) which warm above −4 ∘C, (ii) with ice-filled joints, (iii) with fractured limestone or probably most of the rock types relevant for permafrost rock slope failure, and (iv) with a wide range of slope angles (30–70∘) and orientations of the fracture network (consisting of three joint sets). Here, we present a benchmark model capable of assessing the future destabilisation of degrading permafrost rock slopes.
Stability of Al-bearing superhydrous phase B at the mantle transition zone and the uppermost lower mantle

Abstract We determined the stability and chemical composition of Al-bearing superhydrous phase B at 20–24 GPa and 1400–2000 °C to discuss the mechanism of water transport in the mantle transition zone and uppermost lower mantle at temperatures close to the mantle geotherm. Superhydrous phase B contained significant amounts of Al2O3, from 14 to 32 wt%, and Al-bearing superhydrous phase B remained stable, even at 2000 °C and pressures of approximately 20–24 GPa. Moreover, two types of superhydrous phase B with different chemical compositions coexisted at 20–24 GPa and 1600 °C. The Al2O3 and H2O contents increased, and the MgO and SiO2 contents decreased as the pressure and temperature increased up to 1600 °C. Above 1600 °C, the MgO and Al2O3 contents increased, and the SiO2 and H2O contents decreased as the temperature increased. We found two substitution mechanisms: (1) 2Mg2+ + Si4+ ⇄ 2Al3+ + 2H+ + □Mg (Mg site vacancy) (2Mg2+ = Al3+ + H+ + □Mg):(Si4+ = Al3+ + H+) = 1:1, (2) Si4+ + 16H+ ⇆ 4Mg2+ + 4Al3+. The maximum H2O content of Al-bearing superhydrous phase B is 11.1(3) wt%, which is ~ 1.9 times larger than that of the Mg-end-member. The crystal structures of the two coexisting superhydrous phase B values are expected to be slightly different from each other. The present results indicate that Al-bearing superhydrous phase B can be stable in a subducted slab with a high Al content compared to pyrolite (e.g, chlorite) at temperatures typical of the mantle transition zone and the lower mantle. Thus, water can be transported to the lower mantle by Al-bearing superhydrous phase B in the subducting slab, even at the typical mantle geotherm.
The Role of Religiosity and Spirituality in Motivating and Improving Students’ Performance in Indonesia

Aims: This study aimed to investigate the relationship model of religiosity, spirituality, intrinsic motivation, and extrinsic motivation with students' performance in Indonesian students based on different beliefs or religions in the country. Methodology: This study used a survey method with a questionnaire conducted on 628 students as a sample. The relationship between all variables was tested using Pearson’s correlation and the direct relationship between the independent variables on the dependent variable using multiple linear regression analysis. Furthermore, the mediating model test was conducted using structural equation modeling with a two-step approach. Results: The findings showed that motivation, religiosity, and spirituality affected students’ performance. Furthermore, intrinsic and extrinsic motivation serially mediated the relationship model between religiosity and spirituality with students' performance. Conclusion: This paper addressed the need to understand how to motivate and improve students' performance from a religious and spiritual perspective. The findings of this paper can be used to identify curriculum preparation that includes religiosity in it to increase students' motivation and performance. Furthermore, this paper has demonstrated that religiosity and spirituality are very important for students in Indonesia because they can increase motivation so that student achievement becomes better.
Effect of Temperature on Life History of Bemisia Tabaci (Gennadius) (Homoptera: Aleyrodidae) on Cassava Manihot Esculenta Crantz

The aim of the present study was to evaluate the relationships between environmental temperatures and life-history traits of whitefly Bemisia tabaci on cassava in the Northern part of Vietnam. The influence of temperature on the biological characteristics of whitefly B. tabaci fed on cassava was evaluated at 20ºC, 25ºC, 27. 5ºC, and 30ºC using individual insect rearing methodology. Results of the study showed that the development time from egg to adult of B. tabaci was influenced by temperatures. The data indicated that under different temperatures (20ºC, 25ºC, 27.5ºC, and 30ºC), the life cycle of B. tabaci were 41.46, 28.64, 24.29, and 20.25 days, respectively. The determination of lower developmental threshold and degree days for whitefly development were 11. 2ºC and 344.8 degree-days. There were 14.31 whitefly generations within 1 year on cassava suggesting this plant is a suitable host plant for the development and reproduction of B. tabaci. Female longevity ranged from 4.92 to 10.23 days. The fecundity ranged from 49.3 to 74.0 eggs/female. The mortality rate reached its highest rate of 36.27% at 30ºC. Our results suggested that B. tabaci had high reproduction rates and demonstrated their positive fitness traits on cassava in a wide range of temperatures, being a potential important pest of cassava cultivars.
UNAFLOW: a holistic wind tunnel experiment about the aerodynamic response of floating wind turbines under imposed surge motion

Abstract. Floating offshore wind turbines are subjected to large motions due to the additional degrees of freedom of the floating foundation. The turbine rotor often operates in highly dynamic inflow conditions, and this has a significant effect on the overall aerodynamic response and turbine wake. Experiments are needed to get a deeper understanding of unsteady aerodynamics and hence leverage this knowledge to develop better models and to produce data for the validation and calibration of existing numerical tools. In this context, this paper presents a wind tunnel experiment about the unsteady aerodynamics of a floating turbine subjected to surge motion. The experiment results cover blade forces, rotor-integral forces, and wake. The 2D sectional model tests were carried out to characterize the aerodynamic coefficients of a low-Reynolds-number airfoil with harmonic variation in the angle of attack. The lift coefficient shows a hysteresis cycle close to stall, which grows in strength and extends in the linear region for motion frequencies higher than those typical of surge motion. Knowledge about the airfoil aerodynamic response was utilized to define the wind and surge motion conditions of the full-turbine experiment. The global aerodynamic turbine response is evaluated from rotor-thrust force measurements, because thrust influences the along-wind response of the floating turbine. It is found that experimental data follow predictions of quasi-steady theory for reduced frequency up to 0.5 reasonably well. For higher surge motion frequencies, unsteady effects may be present. The turbine near wake was investigated by means of hot-wire measurements. The wake energy is increased at the surge frequency, and the increment is proportional to the maximum surge velocity. A spatial analysis shows the wake energy increment corresponds with the blade tip. Particle image velocimetry (PIV) was utilized to visualize the blade-tip vortex, and it is observed that the vortex travel speed is modified in the presence of surge motion.
Reputation or Interaction: What Drives Cooperation on Economic Sanctions?

This article studies cooperation on multilateral economic sanctions. Despite low effectiveness and sanction-busting, multilateral economic sanctions are a popular tool of foreign policy. We explore an instrumental approach to sanctions and develop a game theory framework where sender states face a collective action problem when coordinating multilateral coercion. We indicate that cooperation can be achieved through repeated interactions and reputation. We test empirically the two mechanisms with the TIES data on economic sanctions and adherence to past sanction regimes and the Correlates of War data on membership in International Organisations. Our results indicate that reputation is a strong predictor of cooperation on multilateral economic coercion. The effect of repeated interaction appears conditional on reputation; states with poor reputation mediate its effect through repeated interaction.