Miracle-dz/UniFAR-FTUs huggingface dataset:
COMPARATIVE STUDIES OF THE IN VITRO ACTIVITY OF THE FUNGICIDES OXADIXYL AND METALAXYL

The two phenylamide fungicides oxadixyl and metalaxyl were compared in vitro with respect to their activity against a diversity of zoosporic fungi and representative higher fungi. The spectrum of activity of these fungicides, formerly thought to inhibit only members of the Peronosporales, was expanded to include Pythiopsis cymosa in the Saprolegniales and Lagenidium giganteum in the Lagenidiales, both fungi that cannot synthesize their own sterols as is the case with members of the Peronosporales. Zoophagus insidians, a member of the Peronosporales that makes ergosterol, was insensitive to oxadixyl and metalaxyl. The Hyphochytriomycetes showed a sensitivity intermediate between that of sensitive fungi and that of the higher fungi. Different genera and different species among sensitive fungi had varying degrees of sensitivity to oxadixyl and metalaxyl. Sensitivity was also influenced by incubation time, growth medium, and incubation temperature. Stages in the life cycle of Phytophthora palmivora that were sensitive to oxadixyl and metalaxyl included vegetative growth, sporan? gium formation, and sporangium germination. Zoospore behavior, encystment, and cyst germination were not influenced by the two fungicides. Inhibition of germling growth by metalaxyl began less than 90 min after cyst germination. Mitotic divisions occurred at con? centrations ofthe fungicides that gave a 50% inhibition of growth. The results are compared with those of other workers and the significance of the results with respect to control and possible mechanisms of action is discussed.
Leptospirosis and scrub typhus co–infection in febrile patients

Leptospirosis has to be differentiated from other aetiologies of acute febrile illness like scrub typhus, malaria, enteric fever, dengue and spotted fever. Concurrent infection of leptospirosis can occur with typhoid fever, brucellosis and rickettsial infections. A study was done in a tertiary care centre in Eastern India to determine simultaneous presence of infection of leptospirosis and scrub typhus in sera of febrile patients. IgM antibodies to both leptospira and scrub typhus were detected by Enzyme linked immunosorbant assay (ELISA). During the study period of two years a total of 608 serum samples were received for serology for leptospirosis. Out of these samples 26 patients had IgM antibodies to leptospira, of which 11 (42.31%) also had IgM antibodies to scrub typhus. As both leptospirosis and scrub typhus present with similar clinical features, co-infection of these two diseases may occur and it requires molecular methods for confirmation of these cases.
Price and volume relationship in the U.S. livestock futures markets

The objective of this work is to examine the relationship between closing prices and trading volume in the livestock futures markets of lean hogs, live cattle and feeder cattle. The parametric quantile regressions methodology is employed. Daily data between 1/1/2010 and 31/7/2019 were utilized. Findings suggest that the relationship between the two variables is non-linear. Price-volume relationship is positive (negative) under positive (negative) returns. Furthermore, co-movement is weaker at the lower quantiles and stronger at the higher quantiles. Results are in line with the empirical findings of the price-volume relationship in six agricultural futures markets from the study by Fousekis and Tzaferi (2019). This is the first study that utilizes the parametric quantile regressions method in the livestock futures market, in order to examine the returns-volume dependence.
Digestibility, ruminal characteristics, and meat quality of fattening lambs fed different levels of fennel (Foeniculum vulgare) seed powder

The objective of this experiment was to evaluate of effect of fennel seed powder (FSP) on digestibility, ruminal characteristics, and meat quality. In a completely randomized design, three diets containing zero (without FSP), 0.75% and 1.5% FSP were fed to 30 Kermani fattening male lambs (eight months old), with an average initial body weight of 27.5 ± 0.450 kg for 80 days. There was no effect of diets on apparent nutrient digestibility, but dry matter intake (DMI) was higher (P<0.05) for the diets containing FSP. The lambs fed the FSP diets had more final body weight (BW), weight of warm carcass and lean meat than lambs fed control diet (P<0.05). Ruminal pH, and NH3-N and acetic acid concentrations were higher in lambs on FSP diets than in control group (P<0.05). Ruminal protozoal population and propionic acid concentration were lower (P<0.05) in lambs fed FSP than the control diets. The meat fat content decreased but protein content increased in lambs fed on FSP diets. The malondialdehyde concentration in Longissimus dorsi of lambs fed FSP diets was lower compared with the control lambs. The results suggested that fennel seed feeding to fattening lambs, by improving the ruminal fermentation and meat quality, might be a suitable natural antioxidant for the meat production industry.
Aspects of Electrochemically Activated Water Solutions Practical Use

This article analyzes the issue of developing ecologically safe technologies for obtaining the electrochemically activated water solutions for ensuring the rational use of water resources and reducing the volume of discharges of harmful substances into the environment. The necessity of controlling the depth of electrochemical activation for obtaining ecologically safe industrial water solutions and reducing the energy consumption of this process was substantiated. The ecological advantages of electrochemically activated solutions application were presented as compared to the chemical solutions in the technologies of activated carbon surfaces modification to increase the supercapacitors electrode specific capacitance, preparation of the gypsum plaster mixing water to improve the physicochemical properties of gypsum stone, as well as efficiency of use of disinfectant based on the electrochemically activated water solutions solutions, approbated in the sugar production industry. It was experimentally confirmed that the depth of electrochemical activation significantly affects the efficiency of practical use of activated water solutions. The proposed theoretical models allow prediction of the activation modes for solving specific problems.
A Study On Comparison Of Pain Score Between Upper Limb And Lower Limb Fractures

Introduction: Pain is the most common chief complaint of patients presenting to Emergency Department (ED). Pain is not simply a signal for tissue injury, but also a signal to seek repair and recuperation. The aim of this study was to determine whether upper limb (UL) or lower limb (LL) fracture has more pain and to evaluate the association between types of fracture (UL vs LL) with adequacy of pain relief. Methodology: A study was conducted from July to October 2005 in ED, Hospital Universiti Sains Malaysia (HUSM). Patients who fulfill the inclusion criteria were selected. Paramedics in charged were the assistants; at the same time became the observer. The paramedics were not involved in the decision making for pain management. Pain severity score was assessed by using Numeric Rating Scale (NRS). Results: 42 patients were enrolled. 85.7% (n=36) were male and 14.3% were female. Mean age is 29.6 years old. Mean NRS on arrival for UL and LL fractures were 6.47 ± 1.70 and 7.80 ± 2.53 respectively. Mean NRS for mixed fractures (both UL and LL) was 7.60 ± 3.36. There was no statistically significant association between fracture sites and analgesic administration (p value=0.300). There were 70.6% and 70.0% of the patients with UL and LL fractures had adequate pain relief whereas 80% of patients with mixed fractures had adequate pain relief (p value= 0.902). Conclusion: LL and mixed fractures had more pain score on arrival but there was no statistically significant association between fracture sites and analgesics administration and no association between fracture sites with adequacy of pain relief.
Studies on influence of different cropping systems on soil fertility sustenance in the vertic ustropept

A research work was initiated during 2018-19 at Tamil nadu agricultural University with different cropping sequences involving annual crops in three seasons with four cropping sequences along permanent fodder crops such as BN hybrid grass, desmanthus and cenchrus to study the influences of these cropping on soil quality parameters. The results are, the physicochemical do not influenced by cropping sequences. The higher level of organic carbon (5.88 g/kg), available nitrogen (265 kg/ha), available phosphorus of 22.3 kg/ha, available potassium of 598 kg/ha was registered in cowpea-ragi-green manure sequence. The higher value of active soil carbon (685 mg/kg) was recorded in bajra napier (BN) fodder grass. The cowpea-ragi-green manure (GM) recorded higher macro aggregates carbon (6.58 g/kg), higher micro aggregate associated carbon (8.66 g/kg), Higher soil dehydrogenase enzyme activity of 179.3 mg TPF/kg/24 hrs and alkaline phosphatase activity (58.25 PNP ug/g/hr) was observed in cowpea-ragi-GM. The microbial population, bacteria, fungi and actinomycetes are better expressed in cowpea-ragi-GM (52 cfu x 10-6 g/soil, 23 cfu x 10-4 g/soil and 13 cfu x 10-3g/soil.
Effect of experimental phenylketonuria on the development of skin of prenatel and newborn fetuses.

Phenylketonuria (PKU) is a genetic disorder that is characterized by an inability of the body to utilize the essential amino acid, phenylalanine. The disease results from a deficiency in phenylalanine hydroxylase, the enzyme catalyzing the conversion of phenylalanine to tyrosine. The present work studied the Effect of experimental phenylketonuria on the development of skin of prenatel and newborn fetuses.The disease was induced in pregnant rats by daily intragastric administration of 30 mg. DL-a-methylphenylalanine/kg body weight plus 60 mg/kg body weight at 12 h intervals throughout pregnancy till parturition. Treatment with alphamethylphenylalanine/phenylalanine resulted in significant decrease of accumulated body weight gain during pregnancy as well as exhibited marked growth retardation of prenatal fetuses and delivered newborn. The growth retarded fetuses was manifested by decreased body weight, malformed both fore -& hind limb, oedematous skin & superficial hematomas widely spreads in different parts of the body. Vibrissae skin hair were characterized by curved free ends as well as reduction of their size and length. Cornification was retarded . The epidermis attained a considerable thinning with delayed differentiation of epidermal cell layers.The growing hair follicles lacked normal characteristic appearance. These results suggested that exposure of the fetus to high plasma concentrations of phenylalanine caused a delay in the biochemical maturation of the fetal rat.
Trauma-focused treatment outcome for complex PTSD patients: results of an intensive treatment programme

ABSTRACT Background Complex PTSD (CPTSD) has been incorporated in the 11th edition of the International Classification of Diseases (ICD-11) as a mental health condition distinct from PTSD. Objective The objective of the current study is to determine whether individuals classified as having CPTSD can benefit from an intensive trauma-focused treatment, resulting in decreased PTSD and CPTSD symptoms, and loss of diagnoses. Method Patients diagnosed with PTSD (N = 308) took part in an intensive 8-day treatment programme combining prolonged exposure, EMDR therapy, psycho-education, and physical activity. The treatment was not phase-based in that it did not contain a stabilization phase or skill training prior to therapy. CPTSD diagnosis was assessed by means of the International Trauma Questionnaire (ITQ) and PTSD diagnosis was assessed with both the ITQ and CAPS-5. Treatment response was measured with the CAPS-5, PCL-5, and ITQ. Results Symptoms of both PTSD and CPTSD significantly decreased from pre- to post-treatment resulting in a significant loss of CAPS-5 based PTSD (74.0%) and ITQ-based PTSD and CPTSD diagnoses (85.0% and 87.7%, respectively). No adverse events occurred in terms of suicides, suicide attempts, or hospital admissions. Conclusions The results are supportive of the notion that the majority of patients classified as having CPTSD strongly benefit from an intensive trauma-focused treatment for their PTSD.
On generalizations of the Lorentzian distance function Contents

One of the most relevant objects of my study was the Lorentzian distance and some related concepts. This is, however confusingly, not a distance. It’s usual definition in the setting of a smooth Lorentzian manifold is the analogue to it’s Riemannian counterpart, with the principal distinction that it does not satisfy the triangle inequality, but the reverse triangle inequality. This is a direct consequence of the signature of the Lorentzian metric. In this section I will present the 3 different approaches that will be discussed.
Drought Index as Indicator of Salinization of the Salento Aquifer (Southern Italy)

Salento peninsula (Southern Italy) hosts a coastal carbonate and karst aquifer. The semi-arid climate is favourable to human settlement and the development of tourism and agricultural activities, which involve high water demand and groundwater exploitation rates, in turn causing groundwater depletion and salinization. In the last decades these issues worsened because of the increased frequency of droughts, which emerges from the analysis of Standardized Precipitation Index (SPI), calculated during 1949–2011 on the base of monthly precipitation. Groundwater level series and chloride concentrations, collected over the extreme drought period 1989–1990, allow a qualitative assessment of groundwater behaviour, highlighting the concurrent groundwater drought and salinization.
The effect of prestress force magnitude and eccentricity on the natural bending frequencies of prestressed concrete structures

This paper describes the outcome of static 3-point bending testing and output-only experimental modal analysis on 9 post-tensioned concrete beams. Static 3-point bending testing and dynamic impact testing were conducted on each of the 9 beams at diﬀerent levels of post-tensioning force. The Fast Fourier Transform (FFT) was implemented on the dynamic accelerometer impact data, and the fundamental frequencies of the simply supported post-tensioned concrete beams were determined by a peak-picking algorithm at each post-tensioning load level. The tests were repeated 10 times at each impact location to ensure repeatability of the experiment. There were 3 impact locations per post-tensioning load level, and there were 11 post-tensioning load levels at which the beams were tested. A ﬁrst-order linear regression model was then applied to the measured fundamental bending frequencies with increasing post-tensioning load. Statistical signiﬁcance tests were subsequently conducted on the recorded data to determine if any statistically signiﬁcant changes in fundamental bending frequency with increasing post-tensioning load was observed, for both static and dynamic results. The results obtained for the static 3-point bending tests were then compared and contrasted with the results obtained from dynamic testing. No statistically signiﬁcant relationship between natural frequency and post-tensioning load level was found for these uncracked concrete beams.
Avaliação da atividade antifúngica dos óleos essencias de Lippia alba (Mill.) N. E. Brown (Verbenaceae) e Cymbopogon citratus (D.C.) Stapf (Poaceae)

The use of medicinal plants is widespread throughout the world including Brazil, where there is a great variety of species and extensive tradition in its use. The objective of this study was to evaluate the antifungal activity of the following essential oils; Lippia alba (Mill.) N.E. Brown (Verbenaceae), and Cymbopogon citratus (DC) Stapf individually as well as its mixture. The extraction of these essential oils was done with dried leaves, using the technique of distillation by steam suction on the Clevenger apparatus for a period of 3 hours. Antifungal activity was determined by Minimum Inhibitory Concentration (MIC), obtained by micro-dilution techniques and Minimum Fungicidal Concentration (MFC), front strains of Candida albicans (ATCC 10231), Candida tropicalis (ATCC 28707) and Candida parapsilosis (ATCC 22019). From the results obtained, it was found that the essential oils Lippia alba and Cymbopogon citratus showed antifungal activity against all strains of Candida, being that better activity was observed by the essential oil of Cymbopogon citratus. It was also seen that the blend of the essential oils did not strengthen the antifungal activity against the microorganisms that were tested. However, this study was only the first step, requiring new research to assess the interaction between the oils, as well as determine which specific substances are responsible for this activity.
The Practice of Open Innovation by SMEs in the Food Industry

This paper examines the practice of open innovation by Small and Medium-sized Enterprises (SMEs) in the food industry. We adopted a multiple case study approach and conducted in-depth semi-structured interviews with four food SMEs in the Flanders region of Belgium. The results of the analysis show that food SMEs practice open innovation mostly through inbound open innovation activities rather than outbound, mainly due to lack of sufficient resources. Food SMEs typically lack sufficient financial capital, technology, and human capital. Within inbound open innovation activities, collaboration with organizations is found to be a key element for food SMEs’ internal development and innovation of new products.
Cyclosporine Broadens the Therapeutic Potential of Lenalidomide in Myeloid Malignancies

The immunomodulatory drug lenalidomide is used for the treatment of certain hematologic malignancies, including myelodysplastic syndromes (MDS). Lenalidomide interacts with cereblon (CRBN), a component of the CRL4CRBN E3 ubiquitin ligase complex, leading to ubiquitination and subsequent degradation of substrates, such as transcription factor Ikaros (Ikaros family zinc finger 1, IKZF1). With a genome loss of function screen, we recently identified two novel pathways mediated by lenalidomide in MDS. In this review, we summarized the major findings of these two pathways and their clinical implications. Depletion of G protein-coupled receptor 68 (GPR68) or an endogenous calcineurin (CaN) inhibitor, regulator of calcineurin 1 (RCAN1), reversed the inhibitory effect of lenalidomide on MDSL cells, an MDS cell line. Intriguingly, both GPR68 and RCAN1 expression levels were upregulated in MDSL cells after treatment with lenalidomide that was dependent on diminishment of IKZF1, indicating that IKZF1 functioned as a transcription repressor for GPR68 and RCAN1. Mechanistic studies revealed that upregulation or activation of GPR68 induced a Ca2+/calpain pro-apoptotic pathway, while upregulation of RCAN1 inhibited the CaN pro-survival pathway in MDSL cells. Notably, the pharmacological CaN inhibitor, cyclosporine, enhanced the sensitivity to lenalidomide in MDS as well as acute myeloid leukemia (AML). Surprisingly, pretreatment with lenalidomide reversed the immunosuppressive effects of cyclosporine on T lymphocytes. Our studies suggest that lenalidomide mediates degradation of IKZF1, leading to derepression of GPR68 and RCAN1 that activates the Ca2+/calpain pro- apoptotic pathway and inhibits the CaN pro-survival pathway, respectively. Our studies implicate that cyclosporine extends the therapeutic potential of lenalidomide to myeloid malignancies without compromising immune function.
Application of chitosan edible coating for preservation of tomato

Tomato is one of the most widely consumed fresh fruit in the world. It is extremely perishable. Edible coatings serve as the best possible alternative to reduce the post-harvest losses by delaying the ripening of tomato and increasing the shelf life without affecting the quality. Tomatoes were coated by dipping method with different concentrations of chitosan. The effect of this coating on TSS, pH, titratable acidity, shrinkage and lycopene content of tomato were investigated for a period of 30 days at ambient temperatures. Coated tomatoes were firmer, higher in titratable acidity, less decayed. Change in pH and TSS were observed to be less in coated samples than the control fruit at the end of storage. On 20th day of storage, lowest TSS value (5.1% Brix) was recorded in 2.5% chitosan and the highest TSS value (6.8% Brix) was recorded in control. The tomato in control showed a rapid deterioration from 20th day of storage. On the contrary, the coating on tomatoes delayed the ripening and extended the shelf life up to 30 days. From the results, it was concluded that 2.5% chitosan treatment resulted in better extension of the shelf life of tomato on storage when compared 0.5%, 1%, 2% chitosan coatings.
Clinical, Hematobiochemical And Trace-Elements Alterations In Camels With Sarcoptic Mange (Sarcoptes Scabiei Var Cameli) Accompanied By Secondary Pyoderma

Sarcoptic mange is a common, zoonotic and important disease facing camel farming systems with grave economic losses. The present study was applied to estimate the effect of sarcoptic mange on clinical condition, hematobiochemical criteria and trace-element status among camels in Egypt. A total number of thirty dromedary camels (Camelus dromedarius) were investigated in the present study. The animals were divided into fourteen diseased camels affected with sarcoptic mange and sixteen apparently healthy camels. Complete case history and clinical examination included respiration, pulse rates and body temperature was applied. The main clinical manifestations included over thickening of the skin with scales, fissuring, intense itching, unthriftiness, weight loss, and debility. Clinical examination showed significant increase (P≤0.05) and (P≤0.01) for respiration and pulse rates respectively in affected camels. Hematological analysis in diseased camels showed a significant decrease in PCV (P≤0.05), Hb (P≤0.001), RBCs count (P≤0.01), MCHC (P≤0.001) and relative (%) lymphocytic level (P≤0.001) while significant increase was recorded for MCV (P≤0.01), TLC (P≤0.01), relative (%) neutrophils (P≤0.001) and eosinophils levels (P≤0.01). Results of biochemical constituents in affected camels showed a significant decrease (P≤0.001) in total protein, albumin, glucose and zinc levels while A/G ratio showed significant (P≤0.01) decrease. Both serum total iron and copper levels showed a significant (P≤0.05) decrease in diseased camels compared to healthy camels. Skin swab samples revealed Staphylococcus spp. in the majority of mange infected cases indicating secondary pyoderma. In conclusion, sarcoptic mange had a deleterious effect on physical, hematobiochemical condition and trace-element status in camels.
Application of Model-Based Deep Learning Algorithm in Fault Diagnosis of Coal Mills

The coal mill is one of the important auxiliary engines in the coal-fired power station. Its operation status is directly related to the safe and steady operation of the units. In this paper, a model-based deep learning algorithm for fault diagnosis is proposed to effectively detect the operation state of coal mills. Based on the system mechanism model of coal mills, massive fault data are obtained by analyzing and simulating the different types of faults. Then, stacked autoencoders (SAEs) are established by combining the said data with the deep learning algorithm. The SAE model is trained by the fault data, which provide it with the learning and identification capability of the characteristics of faults. According to the simulation results, the accuracy of fault diagnosis of coal mills based on SAE is high at 98.97%. Finally, the proposed SAEs can well detect the fault in coal mills and generate the warnings in advance.