Miracle-dz/UniFAR-FTUs huggingface dataset:
Primary diagnosis, survival and long-term outcome in young horses with problems in the neonatal period

In this study, neonatal disorders of foals in a referral hospital (n=170), survival and further development until the age of at least three years were analysed retrospectively. The most frequent primary diagnosis was septicemia (33%), followed by prematurity (16%), failure of passive transfer (FPT; 13%) and gastro-intestinal problems (8%). Out of 170 foals, 108 survived and were discharged healthy. Survival rate was lowest in premature neonates (22%) and foals with septicemia (55%). In all other groups > 80% of the foals survived and were discharged healthy. The frequency of primary diagnoses did not differ between female and male foals. Only in cases with meconium impaction, statistical significance was nearly reached (2 female, 9 male, p=0.06). Pronounced deviations from normal clinical and laboratory values were mainly found in premature foals (e.g. decreased body temperature, prolonged capillary refill time, immature blood count). For 70 foals, information on development up to an age of at least 3 years was available. Out of these, 42 had been healthy during at least 3years after treatment in the neonatal period. A variety of problems were reported in the remaining 28 foals.
Comparative Study of Potassium Chloride and Sodium Bicarbonate as an adjuvant to Lignocaine Hydrochloride with Adrenaline in Supraclavicular Brachial Plexus Block

This is a double blind randomized clinically controlled comparative study of addition of potassium chloride and sodium bicarbonate to lignocaine hydrochloride with adrenaline in brachial plexus block. 60 patients of ASA I and II of aged between 20 to 60 years of either sex posted for upper limb surgery were randomly allocated into two groups A and B. Group A received 30 ml of lignocaine hydrochloride with adrenaline ( 1:200000) and sodium bicarbonate ( 7.5%w/v). Group B received 30ml of lignocaine hydrochloride with adrenaline (1:200000) and potassium chloride (15%w/v compare). We observed onset of block, duration of block and duration of analgesia. It was observed that in group B onset of sensory block was earlier when compared to group A and it is statistically not significant (3.11±1.6 v/s 5.6±2.83, p value >0.05). Onset of motor block was earlier in group A when compared to group B (9.15±1.87 v/s 13.73±2.05) and this is statistically significant ( p value<0.001). Duration of sensory block (162.66±30.83 v/s 142.25±20.83), duration of motor block (186.83±40.18 v/s 152.25±29.74) and duration of analgesia (276.50±32.14 v/s 218.75±20.15) was prolonged in group B when compared to group A and it is statistically significant (p value<0.001).
A REMARK ON A SUBCLASS OF ANALYTIC FUNCTIONS

In the present paper, we investigate a subclass of analytic functions defined by a multiplier transformation. The class is previously studied by Laura Stanciu and Daniel Breaz [6] for f ∈ A. We here study this class for f ∈ Ap and obtained certain results for starlikeness and convexity of analytic functions f ∈ Ap. We also present correct version of some results of Laura Stanciu and Daniel Breaz [6]. 2010 Mathematics Subject Classification: 30C80, 30C45.
Elite Capture in the Absence of Democracy: Evidence from Backgrounds of Chinese Provincial Leaders∗

This paper analyzes the effect of social ties between a provincial leader and key provincial stakeholders on governance in China. Using province-level panel data for 26 years, we show that party secretaries who built their careers within the province are less predatory towards business and have higher public goods provision, while sustaining the same level of economic growth, compared to those who were appointed to their positions from outside the province. To identify the effect, we exploit exogenous variation in the central leadership combined with the timing of provincial leaders’ term appointments. Evidence suggests that the results are not driven by differences in local knowledge or innate preferences. We interpret the findings as the effect of elite capture on governance. Formally, provincial leaders are accountable only to the center and are given strong incentives to deliver economic growth, possibly at expense of other goals, such as public goods provision. Provincial leaders who built their careers within provinces are bound by implicit contracts with provincial elites, who helped them to power. Preferences of provincial elites in China are closer to those of the general population than that of politicians. Thus, in the absence of democracy, elite capture serves as an imperfect substitute for a local accountability mechanism. ∗We thank Andrei Bremzen, Georgy Egorov, Ronny Freier, Sergei Guriev, Irena Grosfeld, Eliana La Ferrara, David Li, Shang-Jin Wei, and participants of the 13th Annual Conference of the International Society for New Institutional Economics at the University of California at Berkeley, the 3rd Global Institute China-Russia Conference at Tsinghua University, and CEPR workshop of political economy of development for helpful comments. We also thank Ryan Monarch and Lynn Liu for excellent research assistance. †Persson is from Columbia University; Zhuravskaya is from the New Economic School (NES) and the Center for Economic Policy Research (CEPR). Please send correspondence to: Ekaterina Zhuravskaya, New Economic School, 47 Nakhimovsky prospect, 117418 Moscow, Russia, Email: EZhuravskaya@nes.ru, Phone: (7495) 9255002, Fax: (7495) 9255003.
Smoking cessation, version 1.2016 clinical practice guidelines in oncology

Cigarette smoking has been implicated in causing many cancers and cancer deaths. There is mounting evidence indicating that smoking negatively impacts cancer treatment efficacy and overall survival. The NCCN Guidelines for Smoking Cessation have been created to emphasize the importance of smoking cessation and establish an evidence-based standard of care in all patients with cancer. These guidelines provide recommendations to address smoking in patients and outlines behavioral and pharmacologic interventions for smoking cessation throughout the continuum of oncology care.
TMEM16A ameliorates vascular remodeling by suppressing autophagy via inhibiting Bcl-2-p62 complex formation

Rationale: Transmembrane member 16A (TMEM16A) is a component of calcium-activated chloride channels that regulate vascular smooth muscle cell (SMC) proliferation and remodeling. Autophagy, a highly conserved cellular catabolic process in eukaryotes, exerts important physiological functions in vascular SMCs. In the current study, we investigated the relationship between TMEM16A and autophagy during vascular remodeling. Methods: We generated a transgenic mouse that overexpresses TMEM16A specifically in vascular SMCs to verify the role of TMEM16A in vascular remodeling. Techniques employed included immunofluorescence, electron microscopy, co-immunoprecipitation, and Western blotting. Results: Autophagy was activated in aortas from angiotensin II (AngII)-induced hypertensive mice with decreased TMEM16A expression. The numbers of light chain 3B (LC3B)-positive puncta in aortas correlated with the medial cross-sectional aorta areas and TMEM16A expression during hypertension. SMC-specific TMEM16A overexpression markedly inhibited AngII-induced autophagy in mouse aortas. Moreover, in mouse aortic SMCs (MASMCs), AngII-induced autophagosome formation and autophagic flux were blocked by TMEM16A upregulation and were promoted by TMEM16A knockdown. The effect of TMEM16A on autophagy was independent of the mTOR pathway, but was associated with reduced kinase activity of the vacuolar protein sorting 34 (VPS34) enzyme. Overexpression of VPS34 attenuated the effect of TMEM16A overexpression on MASMC proliferation, while the effect of TMEM16A downregulation was abrogated by a VPS34 inhibitor. Further, co-immunoprecipitation assays revealed that TMEM16A interacts with p62. TMEM16A overexpression inhibited AngII-induced p62-Bcl-2 binding and enhanced Bcl-2-Beclin-1 interactions, leading to suppression of Beclin-1/VPS34 complex formation. However, TMEM16A downregulation showed the opposite effects. Conclusion: TMEM16A regulates the four-way interaction between p62, Bcl-2, Beclin-1, and VPS34, and coordinately prevents vascular autophagy and remodeling
TIME MANAGEMENT AND ORGANIZATIONAL EFFECTIVENESS: A STUDY OF MANUFACTURING COMPANIES IN PORT HARCOURT, NIGERIA

The study investigates the relationship between Time Management and Organizational effectiveness in manufacturing firms in Port Harcourt. The study adopted quasi-experimental research design since it is a cross sectional survey. The population of the study is 192, and the study focused on the population since the population size is small. The data were analyzed using Spearman‟s Rank Order Correlation Coefficient Statistic through the use of Statistical Package for Social Sciences (SPSS). The findings revealed a positive and significant relationship between Time Management and Organizational effectiveness. Hence, the study therefore concludes that Time Management affects Organizational effectiveness in manufacturing firms in Port Harcourt, and recommended that management should actively engage in prioritizing that will facilitate and improve organizational effectiveness in the organization. They should also delegate responsibility in order to improve customer‟s satisfaction and organizational effectiveness. They should encourage proper scheduling of work to various units in the organization to ensure organizational effectiveness. Effective organizational structure should be set up for proper control of the organizational resources that will ensure organizational effectiveness in the organizations. The research study could not cover the service organizations. Hence, there is need to examine the extent to which time management affect organizational effectiveness in manufacturing firms in Port Harcourt.
DEV127415 2386..2387

Pankaj Dhonukshe1,*,¶, Fang Huang2,#,*, Carlos S. Galvan-Ampudia2,$,*, Ari Pekka Mähönen1,†, Jürgen Kleine-Vehn3,@, Jian Xu1,‡, Ab Quint2, Kalika Prasad1,£, Jiřı ́ Friml3,¥, Ben Scheres1,μ and Remko Offringa2,§ Section of Molecular Genetics, Department of Biology, Utrecht University, Padualaan 8, 3584CH Utrecht, The Netherlands. Molecular and Developmental Genetics, Institute Biology Leiden, Leiden University, Sylvius Laboratory, Sylviusweg 72, 2333BE Leiden, The Netherlands. Department of Plant Systems Biology, Flanders Institute for Biotechnology, Technologiepark 927, 9052 Ghent, Belgium. These authors contributed equally to this work No longer at this address Present address: Institute of Integrative Biology, University of Liverpool, Crown Street, Liverpool L69 7ZB, UK. Present address: Plant Reproduction and Development, Ens de Lyon, 15 parvis René Descartes BP 7000 69342 Lyon Cedex 07, France. Present address: Institute of Biotechnology, University of Helsinki, P.O. Box 65, FIN-00014, Helsinki, Finland. Present address: Department of Applied Genetics and Cell Biology (DAGZ), Muthgasse 18, 1190 Wien, Austria. Present address: Department of Biological Sciences, Faculty of Sciences, National University of Singapore, 14 Science Drive 4, Singapore 117543. Present address: School of Biology, Indian Institute of Science Education and Research, Thiruvananthapuram 695016, Kerala, India. Present address: Institute of Science and Technology Austria (IST Austria), Am Campus 1, A-3400 Klosterneuburg, Austria. Present address: Plant Developmental Biology, Wageningen University, Postbus 633, 6700AP Wageningen, The Netherlands. Author for correspondence (r.offringa@biology.leidenuniv.nl)
IN-SITU RAMAN SPECTROSCOPY STUDIES OF OXYGEN SPILLOVER AT SOLID OXIDE FUEL CELL ANODES

The present work is centered on the combined studies of anodic processes in electrode-supported solid oxide fuel cells (SOFCs) using in-situ Raman spectroscopic and electrochemical measurements. A possibility to perform direct spectroscopic measurements at the inner electrolyte | anode interface in the case of anode-supported SOFC with polycrystalline thin-film zirconia solid electrolyte was experimentally demonstrated. The application of anodesupported SOFC architecture makes also it possible to significantly extend the range of operating temperatures and current densities across the electrochemical cell. The results confirm a direct incorporation of oxygen anions transported through zirconia electrolyte into the ceria-based anode sublayer, with subsequent fuel oxidation at the cermet anode.
Reliability of Physical Examination, Diagnosis and Treatment of Low-Back Pain by Physiotherapy Practitioners in Some Selected Hospitals in Zambia

Background: Low back pain (LBP) is a common disorder that has great consequences in terms of human sufferings and costs related to treatment, disability and lost productivity world over. Reliable physical examination and diagnosis are a fundamental elements in the effective clinical management of LBP. Clinicians like physiotherapists are expected to base their clinical and treatment decisions on physical examination results and diagnosis of LBP. We carried out a study to evaluate the reliability of the physical examination, diagnosis and treatment of LBP by physiotherapy practitioners in five selected referral hospitals in Zambia. Methodology: A cross sectional study design utilising descriptive correlational techniques were employed for the study. A total of 25 physiotherapy practitioners (n=13 degree and n=12 diploma holders) were recruited for the study. The study included 100 patients aged between 1860 years with LBP referred to the physiotherapy department at five referral hospitals across Zambia. A standardized physical examination form was used by raters to capture the required clinical information. The reliability assessments were done using the intrarater and interrater tests. A total of 50 patients were each examined separately and consecutively by two physiotherapy practitioners (interrater) while the remaining 50 patients were examined by single therapists who repeated the examination on the same patient after three days (intrarater). Data was entered using SPSS version and descriptive statistics and Cohen's kappa statistical test was used to assess the level of agreement between the two clinical findings obtained (minimum κ: 0.61). Results: The interrater and intrarater reliability for the assessment of LBP were; physical examination results (κ: 0.39; fair; range 0.09-0.83) and (κ: 0.62; good; range 0.06-0.94), for diagnosis (κ: 0.65; good; range -0.13-1.00) and (κ: 0.86; very good; range 0.43-1.00) and treatment (κ: 0.66; good; range 0.10-1.00) and (κ: 0.69; good; 0.23-1.00) respectively. Furthermore, the results showed that 14% and 62% of the raters scored above the minimum priori in the interrater and intrarater reliability respectively of physical examination category, while diagnosis had 52% and 92% and treatment had 56% and 60%. Conclusion: Physical examination techniques among physiotherapy practitioners for LBP varied greatly and had inadequate reliability especially interrater relaibility. The diagnosis and treatment of LBP were considered reliable among physiotherapy practitioners from some selected hospitals in Zambia. A clinically applicable, valid and reliable classification system of physical examination for physiotherapy practitioners may be essential for future high quality research studies to be able to demonstrate the efficacy of diagnosis and physiotherapy management of LBP in Zambia.
Innovative stochastic modeling of residential exposure due to a WiFi source placed in uncertain position

This study focused on the exposure evaluation of the electric field 2D spatial distribution of the E-field in a one-floor apartment when a WiFi source is placed in uncertain position. An innovative approach that combines a Principal Component Analysis and Kriging model in order to build space-dependent surrogate models was applied and validated. Results showed the feasibility of the approach.
Test-Anxiety and Self-Esteem as a Predictor of Secondary School Students’ Academic Self-Efficacy in Ekiti State

This study investigated test-anxiety and self-esteem as a predictor of secondary school students’ academic self-efficacy in Ekiti State. It also examined the relationship betweenthe twopsycho-social factors (self-esteem and test-anxiety) and students’ academic self efficacy. The study employed the descriptive research design of the survey type. The population consisted of all students from the public secondary schools in Ekiti central senatorial district of Ekiti State. The sample for this study was 200 students which were selected from four secondary schools using Multistage Sampling technique. A self-structured questionnaire tagged “Psychosocial Factors and Students’ Academic Self-Efficacy Questionnaire (PFSASEQ)” was used to collect relevant data for the study. The face and content validity of the instrument was determined by experts of Test and Measurements and researcher’s supervisor. It was said to have facial relevance and concerned with the subject matter, the instrument claim to measure. The hypotheses postulated were subjected to inferential statistics of Pearson Product Moment Correlation analysis. All the hypotheses were tested at 0.05 level of significance.The findings of the study revealed that there was significant relationship between test-anxiety, self – esteem and students’ academic self – efficacy. Based on the findings of the study, it was recommended among others that students self-esteem can be enhanced and test-anxiety reduced by creating an enabling environment for mentoring where they can practice assertiveness skills which will in turn boost their confidence to perform all academic tasks successfully .
Dance for health: The importance of community engagement and project sustainability

Dance for Health is an intergenerational approach to increasing activity, reducing the risk of obesity, and improving health awareness in an urban community. The purpose of this research was to explore the impact of community engagement in Dance for Health on graduate nurse practitioner (NP) students and inner city high school (HS) students, and to describe the factors that impact project sustainability. Qualitative surveys were administered to all students to explore their experience with community engagement. Attendance was taken and quantitative surveys were administered to community participants to evaluate the factors impacting sustainability of the intervention. We deduced the following themes from the student surveys: 1) Intergenerational togetherness, 2) Positive environment, 3) Increased awareness, 4) HS student leaders, 5) Health careers exposure for HS students, 6) Community exposure for NP students, 7) Rewarding collaboration. Eighty-eight percent of community participants continued to attend the events two months after the University involvement ceased. Community participants most commonly responded that they attended the events because it was good exercise, fun, safe, and made them “feel good”. Students who were involved stated that engagement in a community-driven, culturally relevant intervention enriched their education and leadership skills. To increase this kind of activity and improve community health overtime, universities must promote sustainability of their interventions by partnering with communities to understand their goals and priorities, and providing a culturally relevant, positive environment for physical activity and education.
Kim, M and Lee, CK and Jung, Timothy (2019)Exploring Consumer Behavior in Virtual Reality Tourism Using an Extended Stimulus-Organism-Response

Although virtual reality (VR) is an emerging technology in tourism, little research has conducted on what factors make consumers visit locations presented by VR. To address this gap in the literature, this study developed a theoretical framework including authentic experience, cognitive and affective responses, attachment, and visit intention with VR tourism using a stimulus-organism-response (SOR) theory. The results revealed significant impacts of authentic experience on cognitive and affective responses, indicating that authentic experience is an important factor in VR tourism. The study identified cognitive and affective responses as significant mediators in predicting attachment and visit intention. The results demonstrated that the intention to visit places shown in VR tourism was influenced by attachment to VR. Cognitive response was a stronger influence than affective response on the intention to visit a destination in VR. This study sheds light on why potential tourists visit destinations shown in VR.
Elevated neutrophil-to-lymphocyte and platelet-to-lymphocyte ratios predict post-stroke depression with acute ischemic stroke

Post-stroke depression (PSD) is the most prevalent psychiatric complication of acute ischemic stroke. The neutrophil-to-lymphocyte ratio (NLR) and the platelet-to-lymphocyte ratio (PLR) are indicators of inflammation and are associated with stroke and depression. Therefore, the purpose of the present study was to examine the relationship between NLR/PLR and PSD. Retrospective analysis was carried out in 376 patients with first-ever acute ischemic stroke in the First Affiliated Yijishan Hospital of Wannan Medical College between March 2015 and September 2017. Patients were divided into PSD (n=104; 27.7%) and non-PSD (n=272; 72.3%) groups according to the Diagnostic and Statistical Manual of Mental Disorders-IV criteria at 6 months after stroke. Clinical data were collected retrospectively. NLR and PLR were acquired retrospectively from the routine blood tests performed at admission. A total of 120 healthy volunteers from the physical examination center in the First Affiliated Yijishan Hospital of Wannan Medical College were recruited as controls. Using logistic regression analysis, NLR (≥4.02) and PLR (≥203.74) were independently associated with PSD. NLR, odds ratio (OR) 3.926, 95% confidence intervals (CI, 2.365-7.947), P<0.001; PLR, OR 3.853, 95% CI (2.214-6.632), P=0.002. The ability of the combined index [area under the receiver operating characteristic curve, 0.701; 95% CI (0.622-0.780); P<0.001] to diagnose PSD was greater than that of either ratio alone. Higher NLRs and PLRs (≥4th quartile) were associated with PSD with a 5.79-fold (P<0.001) increase compared with lower levels of both. Higher NLRs and PLRs were found to be associated with depression 6 months after stroke, and the combined index was more meaningful than either alone in the early clinical detection of PSD.
University of Birmingham Costs and benefits of realism and optimism

• Users may freely distribute the URL that is used to identify this publication. • Users may download and/or print one copy of the publication from the University of Birmingham research portal for the purpose of private study or non-commercial research. • User may use extracts from the document in line with the concept of ‘fair dealing’ under the Copyright, Designs and Patents Act 1988 (? ) • Users may not further distribute the material nor use it for the purposes of commercial gain.