Miracle-dz/UniFAR-FTUs huggingface dataset:
Early detection of atrial fibrillation in patients with heart failure reduces the risk of subsequent hospitalization: a subanalysis of the randomized TIM-HF2 trial

Abstract Aims To evaluate the rate of new-onset atrial fibrillation (AF) and the potential improved outcome in heart failure (HF) patients using non-invasive remote patient management (RPM) compared with usual care (UC). Methods and results This analysis assessed a subgroup of 1538 patients of the TIM-HF2 trial with chronic HF, New York Heart Association Class II or III, admission to hospital for HF within 12 months before randomization, and a left ventricular ejection fraction (LVEF) of 45% or lower. Patients with AF in the baseline electrocardiogram (ECG), with an implanted cardiac device, a history of ablation therapy, and recent anticoagulation were excluded, leaving 347 patients for final analysis (RPM = 175; UC = 172). The percentage of days lost due to unplanned cardiovascular hospitalization or death of any cause (primary endpoint of TIM-HF2), the rate of newly detected AF, and the hospitalization rate due to AF were analysed. For patients with new AF, there was a significant reduction for the primary endpoint in the RPM group [5.5%, 95% confidence interval (CI) 0–11.6 vs. UC: 14.6%, 95% CI 8.0–21.2; P < 0.001]. Within the first 3 months, the detection rate of new AF was significantly higher in the RPM group (5.1%) compared with UC (1.2%), P = 0.035. After 1 year, 23 patients (13.1%) assigned to RPM and 12 patients (7.0%) assigned to UC had newly detected AF, P = 0.056. Unplanned hospitalizations related to AF were significantly lower in the RPM group (2 out of 23 patients vs. UC: 10 out of 12 patients; P < 0.001). Conclusion In this subgroup of HF patients in the TIM-HF2 trial, non-invasive daily ECG transmission leads to a four times higher detection rate of new AF compared with UC. This was associated with a significant reduction of days lost due to unplanned cardiovascular hospitalizations, especially hospitalizations related to AF.
Strategic Responses to Digital Disruption in Incumbent Firms – A Strategy-as-Practice Perspective

ABSTRACT Hardly any organization remains unaffected by the digitalization of society and the whole global economy is shaken by disruptive digital innovations (DDI). This calls for strategic responses from incumbent firms to remain relevant in a changing environment. This study explores the phenomenon of digital transformation and the development of digital business strategy in the context of incumbent firms, in this case, the hotel industry. We address the following research questions: 1) How are hotel organizations disrupted by digital innovations? and 2) How do they respond strategically to these disruptions? The research approach consists of multiple longitudinal case studies of two international hotel chains, offering a rich dataset. “Strategy-as-practice” is used as a theoretical lens. The results show three overall organizational responses due to DDI including: 1) relating to a new digital business environment; 2) translating strategy to practices 3) renegotiating value. Contributions include extending the existing literature on digital strategies and responses to digital disruptions in incumbent firms as well as providing implications to practice.
Evidence of the relationship between attention deficit/hyperactivity disorder (ADHD) and emotional abuse in a sample of preschool children

ABSTRACT This study has aimed to evaluate the relationship between preschool attention deficit/hyperactivity disorder (ADHD) and emotional abuse. Fifty-six children with ADHD aged 5 and 6 years and their mothers, and sixty-five children without a diagnosis of ADHD and their mothers have been included in this study. ADHD symptomatology and emotional abuse potential of mothers have been assessed by the Conners’ Parent Rating Scale-Revised-Short Form (CPRS-RS) and the Scale for Emotional Abuse Potential of Parents with Children Aged 3 to 6 (SEAPP-C3-6) respectively. Mothers of children with ADHD had significantly higher causal sub-dimension scores of SEAPP-C3-6 than that of the mothers of the controls. The higher emotional abuse potential scores of mothers have been significantly associated with higher Conners scores, male gender, disruptive behavior disorders comorbidity, low income and parental education level and parental psychopathology. This study has revealed that preschool ADHD is an important risk factor for emotional abuse. Clinicians shall be aware of the emotional abuse potential among children with ADHD.
Concepts for Which We Need Others More: The Case of Abstract Concepts

The capability to form and use concepts is a core component of human cognition. Although all concepts are grounded in sensorimotor processes, more abstract concepts (e.g., “truth”) collect more heterogeneous and perceptually dissimilar exemplars; thus, linguistic interaction and social interaction are particularly crucial for their acquisition and use. Because of their indeterminacy, abstract concepts generate more uncertainty than more concrete concepts; hence, they induce people to monitor their inner knowledge longer and then to consult others to ask for information and negotiate the concept’s meaning. I propose that people need others more for abstract concepts than for concrete concepts: Other people are essential to acquire, process, and use abstract concepts. Conceiving abstract concepts in these terms requires the employment of novel, interactive methods to investigate how people represent them during their use.
A Review on UAV-Based Remote Sensing Technologies for Construction and Civil Applications

UAV-based technologies are evolving and improving at a rapid pace. The abundance of solutions and systems available today can make it difficult to identify the best option for construction and civil projects. The purpose of this literature review is to examine the benefits and limitations of UAV-based sensing systems in the context of construction management and civil engineering, with a focus on camera-based and laser-based systems. The risk factors associated with UAV operations at construction sites are also considered.
Karyotype description and comparative chromosomal mapping of rDNA and U2 snDNA sequences in Eigenmannialimbata and E.microstoma (Teleostei, Gymnotiformes, Sternopygidae)

﻿Abstract The genus Eigenmannia Jordan et Evermann,1896 includes electric fishes endemic to the Neotropical region with extensive karyotype variability and occurrence of different sex chromosome systems, however, cytogenetic studies within this group are restricted to few species. Here, we describe the karyotypes of Eigenmannialimbata (Schreiner et Miranda Ribeiro, 1903) and E.microstoma (Reinhardt, 1852) and the chromosomal locations of 5S and 18S rDNAs (ribosomal RNA genes) and U2 snDNA (small nuclear RNA gene). Among them, 18S rDNA sites were situated in only one chromosomal pair in both species, and co-localized with 5S rDNA in E.microstoma. On the other hand, 5S rDNA and U2 snRNA sites were observed on several chromosomes, with variation in the number of sites between species under study. These two repetitive DNAs were observed co-localized in one chromosomal pair in E.limbata and in four pairs in E.microstoma. Our study shows a new case of association of these two types of repetitive DNA in the genome of Gymnotiformes.
Business Model Innovation in Research and Development: State of the Art and Based on Public Needs

Every institution has business models, but some are not properly realized to benefit and meet the public needs. The aim of the study was to improve the government's existing business models in space technology to meet the public needs. Related studies regarding the issues were reviewed, and personal observation was conducted at the government space institution in Indonesia. The study found that to attain the public needs, the development of the business model in space technology should consider four aspects, research and development expenditures, wellbeing, sustainable cities and communities, and adoption of emerging technologies. Incorporating the four aspects into the existing business model is expected to bring the research and development closer to what the public wants.
Multifunctional Gold Nanoparticles in Cancer Diagnosis and Treatment

Abstract Cancer is the second leading cause of death in the world, behind only cardiovascular diseases, and is one of the most serious diseases threatening human health nowadays. Cancer patients’ lives are being extended by the use of contemporary medical technologies, such as surgery, radiotherapy, and chemotherapy. However, these treatments are not always effective in extending cancer patients’ lives. Simultaneously, these approaches are often accompanied with a series of negative consequences, such as the occurrence of adverse effects and an increased risk of relapse. As a result, the development of a novel cancer-eradication strategy is still required. The emergence of nanomedicine as a promising technology brings a new avenue for the circumvention of limitations of conventional cancer therapies. Gold nanoparticles (AuNPs), in particular, have garnered extensive attention due to their many specific advantages, including customizable size and shape, multiple and useful physicochemical properties, and ease of functionalization. Based on these characteristics, many therapeutic and diagnostic applications of AuNPs have been exploited, particularly for malignant tumors, such as drug and nucleic acid delivery, photodynamic therapy, photothermal therapy, and X-ray-based computed tomography imaging. To leverage the potential of AuNPs, these applications demand a comprehensive and in-depth overview. As a result, we discussed current achievements in AuNPs in anticancer applications in a more methodical manner in this review. Also addressed in depth are the present status of clinical trials, as well as the difficulties that may be encountered when translating some basic findings into the clinic, in order to serve as a reference for future studies.
Pemanfaatan Berbagai Sumber Pupuk Kandang sebagai Sumber N dalam Budidaya Cabai Merah (Capsicum annum L.) di Tanah Berpasir

The aim of the research was to examine the effects of various sources of manure as a nitrogen sources on the cultivation of red chili. The experiment was conducted using experimental methods which are arranged in Complete Randomized Design (CRD) comprised 4 treatments, namely 90 ton of cow manure per hectare, 60 ton of goat manure per hectare, 36 ton of chicken manure per hectare and standard fertilizers (1 ton NPK/hectare and 20 tons of chicken manure/hectare). The results showed that treatment of manure and standards provide similar effects to the real plant height, weight fresh fruit and fruit diameter, but a significantly different effect on the weight of fresh and dry weight of plant biomass, number of fruits per plant, fruit lenght and production red chilies. Treatment of 90 tons of cow manure per hectare gave the bighest production of red chili that is 302.58 grams per plant, but did not differ significantly with treatment of 36 tons of chicken manure per hectare.
Labour Union Practices and its Influence on Performance of Teachers in Public Secondary Schools in Arusha District Council

The labour practices may affect teachers’ performance either positively or negatively. The inability of teachers’ labour union to deliver its mandate has contributed in de-motivating teachers in their work performance. The study sought to; highlight the labour union practices in secondary schools and examine the influence of labour union practices on work performance of teachers in public secondary school in Arusha district. The study was guided by Social Action Theory by Bowey. The study used convergent parallel mixed method design whereby the study converges or merges quantitative and qualitative data in order to provide a comprehensive analysis of the study problem. Data were collected using the questionnaire, structured interview, and documentary review. The sample size consisted of 126 respondents. Reliability (r = 0.67) of the instrument was tested using Cronbach Alpha. Quantitative data was analysed using descriptive statistics in the SPSS version 20 and results were presented in tables of frequencies and percentages. Qualitative data was analysed thematically alongside research questions. The study reveals that Tanzania Teachers’ union (TTU) fights for teachers’ job security, defending their rights, participating in collective bargaining agreement on behalf of teachers and advocating for teachers’ salary increment. Moreover, the findings reveal that lack of teachers’ job promotions de-motivate them while conducive working environment inspires teachers. The study recommends that teachers need to support the union fully since the union’s strength is obtained through its membership, the teachers as the members of TTU need to join forces together and exhibit solidarity.
How to better incorporate geographic variation in Airbnb price modeling?

Since entering the Chinese market in 2015, Airbnb has become a major player in the Chinese home-sharing arena. This article uses data from 8012 active Airbnb listings in Shanghai and presents three models (linear regression, geographically weighted regression, and random forest) to study the determinants of Airbnb listing prices and incorporate geographic variation in price modeling. Results show that property quality plays a key role in shaping listing prices. Due to Airbnb’s distinctions from traditional lodging in both features and business models, Airbnb pricing determinants differ accordingly. For example, location conditions were found to have a limited impact in regions with established transportation networks. Among the three models, random forest performed best in terms of prediction accuracy. Lastly, practical implications are discussed.
Modeling, Optimization, and Characterization of High Concentration Photovoltaic Systems Using Multijunction Solar Cells

Recent advancements in the development of high-efficiency multijunction solar cells have led to a renewed interest in the design and implementation of high concentration photovoltaic systems. With the emergence of novel materials and design structures, understanding the operation of multijunction solar cells has become a challenging task. Modeling and simulation hence play an important role in the analysis of such devices. In this dissertation, techniques for accurate optoelectrical modeling of concentrating photovoltaic systems, based on multijunction solar cells, are proposed. A 2-dimensional, distributed circuit model is proposed, parametrized to values obtained by numerical modeling of three multijunction cell designs, namely: a three-junction, lattice matched design, a three-junction lattice-mismatched, inverted metamorphic design, and a four-junction, lattice matched design. Cell performance for all the three designs is evaluated under both uniform and nonunifom illumination profiles at high concentrations and efficiency enhancement by optimizing finger spacing is proposed. The effect of luminescent coupling from higher bandgap subcells is also determined. Fresnel-lens based, refractive concentrating optical systems are modeled and optimized using an optical ray-tracing simulator at two different concentrations, with and without a secondary optical element. The corresponding optical efficiency, acceptance angle, and the degree of nonuniformity are determined for each optical system. An integrated approach, combining optical design with electrical modeling is proposed for optimizing the multijunction solar cell in tandem with the corresponding concentrating optics. The approach is validated by on-sun, acceptance angle measurements, using a three-junction, ii lattice-matched cell. Also, temperature effects are modeled and are experimentally validated for a threejunction, lattice-matched design. Experimental results with a single-junction, dilute-nitride cell, targeted for four-junction operation, are presented as well. A modified distributed circuit model is used for analysis of temperature effects in a four-junction solar cell, and the results under both uniform and nonuniform temperature profiles are presented. When implemented, the designs and their corresponding analyses, may result in new insights into the development of CPV systems, thereby enabling enhanced efficiencies at higher concentrations.
A review of the constant strain-rate stress corrosion cracking test. Discussion

A review of six years operational experience in using the slow strain test procedure has indicated several unique advantages associated with dynamic strain techniques and also identified an area of limitation. The chief advantage of the dynamic slow strain test procedure is that it is much more aggressive in producing stress corrosion cracking (SCC) than conventional constant-strain or constant-load tests, so that the testing time is considerably reduced. The procedure reduces the incubation period for crack nucleation by virtue of continuous straining above the elastic limit on smooth surfaces, and avoids the pitfalls associated with reducing incubation times by means of precracking and other methods. With the latter methods, marked chemical inhomogeneities in an environment have been observed so that spurious results are obtained. The slow strain test is also ideally suited, on a "go-no-go" basis, for rapid sorting or screening of environment/metal or environment/metallurgical-condition combinations which can produce SCC. However, the test is not suitable for ranking materials with regard to their resistance to SCC when the strength levels and microstructure vary widely. Furthermore, because of the test severity, discretion must be exercised in translating susceptibility to SCC observed in the laboratory to anticipated performance in service.
The Role of the Metabolism of Zinc and Manganese Ions in Human Cancerogenesis

Metal ion homeostasis is fundamental for life. Specifically, transition metals iron, manganese and zinc play a pivotal role in mitochondrial metabolism and energy generation, anti-oxidation defense, transcriptional regulation and the immune response. The misregulation of expression or mutations in ion carriers and the corresponding changes in Mn2+ and Zn2+ levels suggest that these ions play a pivotal role in cancer progression. Moreover, coordinated changes in Mn2+ and Zn2+ ion carriers have been detected, suggesting that particular mechanisms influenced by both ions might be required for the growth of cancer cells, metastasis and immune evasion. Here, we present a review of zinc and manganese pathophysiology suggesting that these ions might cooperatively regulate cancerogenesis. Zn and Mn effects converge on mitochondria-induced apoptosis, transcriptional regulation and the cGAS-STING signaling pathway, mediating the immune response. Both Zn and Mn influence cancer progression and impact treatment efficacy in animal models and clinical trials. We predict that novel strategies targeting the regulation of both Zn and Mn in cancer will complement current therapeutic strategies.
Perceived stress, stigma, and social support among Nepali health care workers during COVID-19 pandemic: A cross-sectional web-based survey

The COVID-19 pandemic has caused immense psychological distress among Health Care Workers (HCWs). HCWs have been stigmatized by people at their workplace and community, fearing that health care workers are the sources of spreading the virus. This study aimed to assess the perceived stress, stigma, and social support of Nepali health care workers during the COVID-19 pandemic. A web-based cross-sectional survey was conducted among 380 Nepali HCWs. Perceived stress was measured using Perceived Stress Scale (PSS-10). The questionnaire related to stigma was derived from a study conducted to measure stigma among HCWs during the Middle East respiratory syndrome coronavirus (MERS-CoV) outbreak. Furthermore, perceived social support was measured by Oslo Social Support Scale (OSSS-3). Associated factors were examined using Chi-square tests followed by multivariate logistic regression analyses at the significance level of 0.05. This study illustrated that nearly half (44.2%) of the respondents perceived poor social support. Similarly, almost 3% of the HCWs experienced high perceived stress, whereas 87.6% perceived moderate stress, and 35% of the HCWs felt stigmatized. Nepali healthcare workers experienced perceived stress, social stigma, and social support in various severity levels during the COVID-19 pandemic. COVID-19 emergency is emotionally difficult and where psychological distress can jeopardize outcomes and affect work performance. Appropriate psychological interventions are needed to promote the mental well-being of the healthcare workers.
Quarkonium production in p+p collisions at RHIC and LHC

Quarkonium production mechanism is still an unresolved question. This paper provides an overview of recent quarkonium production studies performed at RHIC and LHC in p + p collisions at a wide range of collision energies. After a brief explanation of representative theoretical models, experimental results of the quarkonium spectra and polarizations are presented with comparison to the model calculations. The spectra are overall rather well described by production model calculations, with a few exceptions, while no significant polarization is observed beyond large uncertainties for J/ψ and ϒ, and thus no constraint on the models is obtained at present. Recently, new observables have been measured such as charged particle multiplicity dependence of quarkonium production, which provides a way to understand the interplay between hard and soft processes, and associated production of quarkonium (J/ψ in jets and double production), which provides more information about production mechanism. A trend of non-linear increase of quarkonium production with increasing the particle multiplicity is observed both at RHIC and LHC, but it is reproduced by most models and further studies and more data are needed in order to differentiate them. Meanwhile, the first measurements of J/ψ in jets show that it is produced with larger activity within a jet than simulated by PYTHIA. A comment on the study of J/ψ-hadron femtoscopic correlations to measure their mutual interaction is also given. In summary, the production mechanism remains a puzzle, but more precise studies will be possible with upcoming RHIC and LHC runs.
Farm-scale biomass pelletizer performance for switchgrass pellet production.

Abstract. The impact of feedstock characteristics (moisture content, additive content) and operational parameters (die temperature, pelletizer speed) on pellet quality, plugging tendency, and pelletizer energy use was investigated for a small-scale pelletizer, suitable for on-farm use (~70 kg h-1 rated output). Ground switchgrass () was prepared in small (