Miracle-dz/UniFAR-FTUs huggingface dataset:
Predator Group Composition Indirectly Influences Food Web Dynamics through Predator Growth Rates

Considerable theoretical work predicts that intraspecific trait variation can have profound ecological consequences by altering species interactions. Because of their high flexibility, behavioral traits may be especially relevant in mediating how species respond to one another, thus affecting food web dynamics and ecosystem functioning. However, empirical evidence supporting this idea is limited. Here, we generated predator groups where we manipulated the composition of behavioral types within the groups to assess effects on predator growth rates, prey communities, basal resources, and ecosystem functioning in replicated outdoor ponds. Using European perch (Perca fluviatilis), we created three types of predator populations: two where all individuals expressed either bold or shy phenotypes and one that contained a mix of individuals of the two behavioral types. Bold perch grew faster in mixed populations, indicating that predator growth depends on each individual’s behavioral type and that of its group members. However, there was no evidence that the behavioral composition of the perch population directly altered the dynamics of lower trophic levels. Instead, final perch biomass, not behavioral composition, had the strongest influence on lower trophic levels. Thus, the central question may not be whether predator behavior matters at all for trophic dynamics but rather when behavioral effects will predominate over effects of other influences, such as predator biomass variation.
Student Satisfaction with Online Learning during the COVID-19 Pandemic: A Study at State Universities in Sri Lanka

This quantitative study investigated the determinants of students’ satisfaction with their online learning experience at Sri Lankan universities during the COVID-19 pandemic. The data was collected from 1376 undergraduates enrolled in various courses in humanities and social sciences at three state-owned universities in the country. The results of the Structural Equation Modeling (SEM) revealed that the independent variables of the model, namely perceived learner motivation, perceived challenges of e-learning, and interaction significantly affected students’ satisfaction with their new online learning experience. Out of the three variables, learner motivation exerted the strongest effect on students’ satisfaction, implying the crucial role self-regulated learning—characterized by motivation—plays in online learning environments. The study has several implications for both creating and ensuring the long-term sustainability of productive and student-friendly online learning spaces in higher education.
Seismic performance of new adobe bricks masonry: Design and experiment

At present, adobe houses with traditional characteristics are still widely used in rural areas in western China, but their seismic performance is relatively poor, and they often suffer serious damage under earthquake. To improve the seismic performance of traditional adobe buildings while retaining the characteristics of residential buildings, the mechanical properties of compressed earth blocks (CEB) were tested in this study, and the microstructure characteristics of CEB after failure were analyzed by electron microscope. On this basis, six adobe wall specimens were designed and tested by quasi-static loading to investigate the influence of core columns and different types of bricks on its seismic performance. The results show that the core column can improve the bearing capacity and shear capacity of hollow CEB, and it can also significantly increase the bearing capacity, energy dissipation capacity, and ductility of CEB wall. In general, the adobe wall with core columns shows excellent seismic performance, which can provide a new choice for improving the seismic performance of the adobe house.
A Sex-Stratified Analysis of Monocyte Phenotypes Associated with HIV Infection in Uganda

Women with HIV may experience higher rates of non-AIDS comorbidities compared to men with HIV, but the underlying mechanisms are not well understood. We investigated sex-related differences in the effects of HIV on monocyte phenotypes within the Ugandan Study of HIV effects on the Myocardium and Atherosclerosis (mUTIMA). Of 133 participants who provided blood for flow cytometry assays, 86 (65%) were women and 91 (68%) were persons living with HIV (PLWH) on antiretroviral therapy. The median age was 57 (interquartile range, 52–63) years. PLWH exhibited a lower proportion of circulating CD14+CD16- classical monocytes (66.3% vs. 75.1%; p < 0.001), and higher proportion of CD14+CD16+ inflammatory monocytes (17% vs. 11.7%; p = 0.005) compared to HIV-uninfected participants. PLWH had an increased expression of the chemokine receptor CX3CR1 in total monocytes (CX3CR1+ monocytes, 24.5% vs. 4.7%; p < 0.001) and monocyte subsets. These findings were generally similar when analyzed by sex, with no significant interactions between sex and HIV status in adjusted models. Our data show that the inflammatory monocyte subset is expanded and monocyte CX3CR1 chemokine receptor expression is enhanced among PLWH, regardless of sex. Whether these parameters differentially affect risk for non-AIDS comorbidities and clinical outcomes in women with HIV requires additional investigation.
The Effectiveness of Cochlear Implantation for Children of Hereditary Deafness: A Multicenter Retrospective Study

Aim To study the effectiveness of cochlear implantation in deaf children with gene mutation. Method 420 children from three medical centers with cochlear implants were selected. Before wearing the cochlear implant and 6 months after wearing the cochlear implant, the children's rehabilitation efficacy was evaluated through categories of auditory performance (CAP) and speech intelligibility rating (SIR). The SSF-MCDI and MUSS before and after the treatment were also compared. Results The CAP and SIR scores of the children after the intervention were higher than those before the intervention (P < 0.05). Univariate analysis found that the age of cochlear implantation, parents' education level, and monthly family income were all influencing factors of the CAP score of children with prelingual cochlear implantation (P < 0.05). Multivariate logistic regression analysis shows that the age of cochlear implantation <5 years, parents' education level, and monthly household income are all independent risks of CAP scores in children with prelingual deaf cochlear implantation. Univariate analysis found that the age of cochlear implantation, parents' education level, and monthly household income are all based on the SIR scores of children with prelingual cochlear implantation. Multivariate logistic regression analysis can be obtained: the age of cochlear implantation less than 5 years, the education level of parents, and the monthly family income are independent risk factors for SIR scores in children with prelingual deaf cochlear implantation (P < 0.05). Conclusion The rehabilitation effect of cochlear implants is significant, and the age of cochlear implantation, parents' education level, and monthly family income are all related factors that affect the rehabilitation effect.
Using Venn Diagrams to Evaluate Digital Contact Tracing: Panel Survey Analysis

Background Mitigation of the spread of infection relies on targeted approaches aimed at preventing nonhousehold interactions. Contact tracing in the form of digital proximity tracing apps has been widely adopted in multiple countries due to its perceived added benefits of tracing speed and breadth in comparison to traditional manual contact tracing. Assessments of user responses to exposure notifications through a guided approach can provide insights into the effect of digital proximity tracing app use on managing the spread of SARS-CoV-2. Objective The aim of this study was to demonstrate the use of Venn diagrams to investigate the contributions of digital proximity tracing app exposure notifications and subsequent mitigative actions in curbing the spread of SARS-CoV-2 in Switzerland. Methods We assessed data from 4 survey waves (December 2020 to March 2021) from a nationwide panel study (COVID-19 Social Monitor) of Swiss residents who were (1) nonusers of the SwissCovid app, (2) users of the SwissCovid app, or (3) users of the SwissCovid app who received exposure notifications. A Venn diagram approach was applied to describe the overlap or nonoverlap of these subpopulations and to assess digital proximity tracing app use and its associated key performance indicators, including actions taken to prevent SARS-CoV-2 transmission. Results We included 12,525 assessments from 2403 participants, of whom 50.9% (1222/2403) reported not using the SwissCovid digital proximity tracing app, 49.1% (1181/2403) reported using the SwissCovid digital proximity tracing app and 2.5% (29/1181) of the digital proximity tracing app users reported having received an exposure notification. Most digital proximity tracing app users (75.9%, 22/29) revealed taking at least one recommended action after receiving an exposure notification, such as seeking SARS-CoV-2 testing (17/29, 58.6%) or calling a federal information hotline (7/29, 24.1%). An assessment of key indicators of mitigative actions through a Venn diagram approach reveals that 30% of digital proximity tracing app users (95% CI 11.9%-54.3%) also tested positive for SARS-CoV-2 after having received exposure notifications, which is more than 3 times that of digital proximity tracing app users who did not receive exposure notifications (8%, 95% CI 5%-11.9%). Conclusions Responses in the form of mitigative actions taken by 3 out of 4 individuals who received exposure notifications reveal a possible contribution of digital proximity tracing apps in mitigating the spread of SARS-CoV-2. The application of a Venn diagram approach demonstrates its value as a foundation for researchers and health authorities to assess population-level digital proximity tracing app effectiveness by providing an intuitive approach for calculating key performance indicators.
EGFRK 521 mediates resistance to Cetuximab in head and neck cancer

EGFRK521 mediates resistance to Cetuximab in head and neck cancer 1 Friederike Braig, Malte Kriegs, Minna Voigtlaender, Beate Habel, Tobias Grob, Karina 2 Biskup, Veronique Blanchard, Markus Sack, Anja Thalhammer, Isabel Ben Batalla, Ingke 3 Braren, Simon Laban, Antje Danielczyk, Steffen Goletz, Elzbieta Jakubowicz, Bruno 4 Märkl, Martin Trepel, Rainald Knecht, Kristoffer Riecken, Boris Fehse, Sonja Loges, 5 Carsten Bokemeyer, and Mascha Binder 6 7 1 Department of Oncology and Hematology, BMT with section Pneumology, University Medical 8
Perceived Effects of Climate Change and Extreme Weather Events on Forests and Forest-Based Livelihoods in Malawi

The emerging risks and impacts of climate change and extreme weather events on forest ecosystems present significant threats to forest-based livelihoods. Understanding climate change and its consequences on forests and the livelihoods of forest-dependent communities could support forest-based strategies for responding to climate change. Using perception-based assessment principles, we assessed the effects of climate change and extreme weather events on forests and forest-based livelihood among the forest-dependent communities around the Mchinji and Phirilongwe Forest Reserves in the Mchinji and Mangochi districts in Malawi. Content analysis was used to analyze qualitative data. The impact of erratic rainfall, high temperatures, strong winds, flooding, and droughts was investigated using logistic regression models. The respondents perceived increasing erratic rainfall, high temperatures, strong winds, flooding, and droughts as key extreme climate events in their locality. These results varied significantly between the study sites (p < 0.05). Erratic rainfall was perceived to pose extended effects on access to the forest in both Phirilongwe in Mangochi (43%) and Mchinji (61%). Climate change was found to be associated with reduced availability of firewood, thatch grasses, fruits and food, vegetables, mushrooms, and medicinal plants (p < 0.05). Erratic rainfall and high temperatures were more likely perceived to cause reduced availability of essential forest products, and increased flooding and strong winds were less likely attributed to any effect on forest product availability. The study concludes that climate change and extreme weather events can affect the access and availability of forest products for livelihoods. Locally based approaches such as forest products domestication are recommended to address threats to climate-sensitive forest-based livelihoods.
ER Morphology in the Pathogenesis of Hereditary Spastic Paraplegia

The endoplasmic reticulum (ER) is the most abundant and widespread organelle in cells. Its peculiar membrane architecture, formed by an intricate network of tubules and cisternae, is critical to its multifaceted function. Regulation of ER morphology is coordinated by a few ER-specific membrane proteins and is thought to be particularly important in neurons, where organized ER membranes are found even in the most distant neurite terminals. Mutation of ER-shaping proteins has been implicated in the neurodegenerative disease hereditary spastic paraplegia (HSP). In this review we discuss the involvement of these proteins in the pathogenesis of HSP, focusing on the experimental evidence linking their molecular function to disease onset. Although the precise biochemical activity of some ER-related HSP proteins has been elucidated, the pathological mechanism underlying ER-linked HSP is still undetermined and needs to be further investigated.
Beneficial effects of a nobiletin‐rich formulated supplement of Sikwasa (C. depressa) peel on cognitive function in elderly Japanese subjects; A multicenter, randomized, double‐blind, placebo‐controlled study

Abstract Background Nobiletin exerts beneficial effects on cognitive function in various animal models of Alzheimer's disease. The present study aimed to investigate the benefits and safety of a combination food of nobiletin‐rich extract from C. depressa peel for healthy elderly subjects. Methods The nobiletin‐containing test food (Nobilex®) comprised high‐purity nobiletin powder combined with dried root powder of K. parviflora and dried lead powder of P. japonicum and was administered to elderly Japanese subjects once a day for 16 weeks. The Japanese version of the Wechsler Memory Scaled‐Revised (WMS‐R) was used as a primary evaluation item for the assessment of global memory. Data from a protocol‐matched population (Per Protocol Set: PPS) (n = 108) were analyzed. Results The scores of “general memory” or “visual memory” in the indices of WMS‐R were significantly higher in the nobiletin‐containing test food group than in the placebo group. The difference in the total WMS‐R score was significantly higher in the test‐food group (9.0 ± 7.20) than in the placebo group (5.9 ± 7.70). An age‐stratified analysis of the WMS‐R test showed similar changes in subjects aged ≦74 years to those in the overall subject population. In the stratified analysis involving subjects with an MMSE‐J score of between 24 and 28, the “figural memory” subscale score in WMS‐R was significantly higher in the test food group than in the placebo group. Conclusion The present results indicate that the nobiletin‐containing test food is beneficial for improving memory dysfunction in healthy elderly subjects.
Determining the role of service quality, trust and commitment to customer loyalty for telecom service users: a PLS-SEM approach

PurposeThe purpose of this paper is to determine the role of service quality (SQ), trust and commitment to customer loyalty (CL) for telecom service users. Further, the moderating role of gender, marital status and connection type within the model was tested.Design/methodology/approachA measurement model was created based on valid 615 responses from Indian TSUs for SQ, trust, commitment and loyalty with the help of partial least squares structural equation modeling (PLS-SEM). Multi-group analysis (MGA) was conducted to understand the moderating effect of marital status, gender and connection type within the model.FindingsThe results suggest that, out of five dimensions of SQ, only responsiveness, assurance and empathy have a significant positive relationship with both commitment and trust. Tangibility has a significant positive relationship with trust only. Both commitment and trust have a significant impact on loyalty. It was noticed that both commitment and trust act as mediators between three SQ dimensions (assurance, empathy and responsiveness) and CL. MGA revealed that empathy and responsiveness positively induce trust in telecom users who are single. Whereas, assurance increases commitment toward telecom service providers in married users. Assurance and empathy significantly contribute toward commitment and trust, respectively, in male users as compared to females. Empathy was found important for postpaid users for trust-building, whereas trust was found to be more important for prepaid users to stay loyal to the service provider.Originality/valueThis article contributes toward understanding the role of SQ, trust and commitment to CL moderated by marital status, gender and connection type in an integrated model concerning telecom service.
Optimization of the Frying Temperature and Time for Preparation of Healthy Falafel Using Air Frying Technology

Air-frying is an innovative technique for food frying that uses hot air circulation to prepare healthy products. The objectives of this study were to establish simplified models to reflect the efficacy of the air frying process at varying temperatures and times on the quality attributes of falafel, and to optimize the frying conditions for producing air-fried falafel. Moisture content, color, fat content, hardness, and sensory evaluation of the fried falafel were analyzed under varied temperatures (140 °C, 170 °C, and 200 °C) and time periods (5 min, 10 min, and 15 min). Statistical analysis was then applied to obtain the best fit model that can describe the properties of fried falafel. Results indicated that moisture content, fat content, and L*-value of air-fried falafel were adversely related to the frying temperature and time, but the hardness and ΔE of fried falafel were increased as the frying temperature and time increased. Moreover, an increase followed by a decrease was shown for the appearance, aroma, crispness, taste, and overall preference scores with the increase in frying temperature and time. The regression analysis showed that the proposed models could be properly used for predicting the properties of the fried falafel. In addition, the overlaid plots resulted in the optimum frying temperature of 178.8 °C and time of 11.1 min. Interestingly, the fat content of the air-fried falafel reduced by 45% at optimal frying conditions compared with that for the deep-fat fried one at 180 °C for 7 min (control). In comparison, the air-fried falafel was lower in fat content, higher in hardness with more acceptable appearance and crispness scores than deep-fat fried falafel. Such information could be beneficial to the manufacturers of the falafel to produce an optimal and healthy product.
A Composite Initialization Method for Phase Retrieval

Phase retrieval is a classical inverse problem with respect to recovering a signal from a system of phaseless constraints. Many recently proposed methods for phase retrieval such as PhaseMax and gradient-descent algorithms enjoy benign theoretical guarantees on the condition that an elaborate estimate of true solution is provided. Current initialization methods do not perform well when number of measurements are low, which deteriorates the success rate of current phase retrieval methods. We propose a new initialization method that can obtain an estimate of the original signal with uniformly higher accuracy which combines the advantages of the null vector method and maximal correlation method. The constructed spectral matrix for the proposed initialization method has a simple and symmetrical form. A lower error bound is proved theoretically as well as verified numerically.
Daily Physical Activity and Sleep Measured by Wearable Activity Trackers during the Coronavirus Disease 2019 Pandemic: A Lesson for Preventing Physical Inactivity during Future Pandemics

Wearable activity trackers are devices that are comfortably worn on the body and are designed to be effective in monitoring daily physical activity and improving physical fitness of the wearer. This review aimed to investigate the impact of the coronavirus disease 2019 (COVID-19) pandemic on physical activity measured using wearable activity trackers and discuss future perspectives on wearable activity trackers during pandemics. Daily physical activity was significantly decreased during the COVID-19 pandemic. The implementation of strict public health measures, such as total lockdown, can decrease people’s physical activity by 50% or more of that prior to the lockdown. Physical inactivity is significantly associated with several health problems, including obesity, diabetes, cardiovascular disease, and cancers; therefore, an effective healthcare system to prevent physical inactivity during pandemics should be established. It is essential to create a network between healthcare organizations and wearable activity tracker users to monitor real-time health status and prepare for the future pandemic.
Beware the rebound effect: regional anesthesia increases opioid utilization after humerus fracture surgery

Introduction Regional anesthesia (RA) is used reduce pain in proximal humerus and humeral shaft fracture surgery. The study hypothesis was that RA would decrease opioid demand in patients undergoing fracture surgery. Materials and methods Opioid demand was recorded in all patients ages 18 and older undergoing proximal humerus or humeral shaft fracture surgery at a single, Level I trauma center from 7/2013 – 7/2018 (n = 380 patients). Inpatient opioid consumption from 0–24, 24–48, and 48–72 h and outpatient opioid demand from 1-month pre-operative to 90-days post-operative were converted to oxycodone 5-mg equivalents (OE's). Unadjusted and adjusted models were constructed to evaluate the impact of RA and other factors on opioid utilization. Results Adjusted models demonstrated increases in inpatient opioid consumption in patients with RA (6.8 estimated OE's without RA vs 8.8 estimated OE's with RA from 0–24 h post-op; 10 vs 13.7 from 24–48 h post-op; and 8.7 vs 11.6 from 48–72 h post-op; all p < 0.05). Estimated cumulative outpatient opioid demand was significantly higher in patients with RA at all timepoints. Discussion In proximal humerus and humeral shaft fracture surgery, RA was associated with increased inpatient and outpatient opioid demand after adjusting for baseline patient and treatment characteristics.
An empirical study of drivers for the adoption of logistics innovation

ABSTRACT By drawing on a large representative sample of German firms, we examine patterns and drivers of logistics innovation. We find that firm size, R&D intensity, product innovation, engagement in international markets, and competitive pressure are all positively related to the probability that a firm introduces logistics innovation and to the breadth of adoption across different types of logistics innovation. However, specific notable differences arise: digital logistics innovation is mainly adopted by larger firms and in response to cost and performance motives. In contrast, the adoption of environmental logistics innovation responds more strongly to market pressure.