Miracle-dz/UniFAR-FTUs huggingface dataset:
The Putative Auto-Inhibitory Domain of Durum Wheat Catalase (TdCAT1) Positively Regulates Bacteria Cells in Response to Different Stress Conditions

Catalase is a crucial enzyme in the antioxidant defense system protecting organisms from oxidative stress. Proteins of this kind play important roles in controlling plant response to biotic and abiotic stresses by catalyzing the decomposition of H2O2. The durum wheat catalase 1, TdCAT1, has been previously isolated and characterized. Here, using bio-informatic analysis, we showed that durum wheat catalase 1 TdCAT1 harbors different novel conserved domains. In addition, TdCAT1 contains various phosphorylation residues and S-Nitrosylation residues located at different positions along the protein sequence. TdCAT1 activity decreased after treatment with λ−phosphatase. On the other hand, we showed that durum wheat catalase 1 (TdCAT1) exhibits a low CAT activity in vitro, whereas a deleted form of TdCAT1 has better activity compared to the full-length protein (TdCAT460), suggesting that TdCAT1 could present a putative autoinhibitory domain in its C-terminal portion. Moreover, we showed that TdCAT1 positively regulates E. coli cells in response to salt, ionic and osmotic stresses as well as heavy metal stress in solid and liquid mediums. Such effects had not been reported and lead us to suggest that the durum wheat catalase 1 TdCAT1 protein could play a positive role in response to a wide array of abiotic stress conditions.
Impaired Mucosal Homeostasis in Short-Term Fiber Deprivation Is Due to Reduced Mucus Production Rather Than Overgrowth of Mucus-Degrading Bacteria

The gut mucosal environment is key in host health; protecting against pathogens and providing a niche for beneficial bacteria, thereby facilitating a mutualistic balance between host and microbiome. Lack of dietary fiber results in erosion of the mucosal layer, suggested to be a result of increased mucus-degrading gut bacteria. This study aimed to use quantitative analyses to investigate the diet-induced imbalance of mucosal homeostasis. Seven days of fiber-deficiency affected intestinal anatomy and physiology, seen by reduced intestinal length and loss of the colonic crypt-structure. Moreover, the mucus layer was diminished, muc2 expression decreased, and impaired mucus secretion was detected by stable isotope probing. Quantitative microbiome profiling of the gut microbiota showed a diet-induced reduction in bacterial load and decreased diversity across the intestinal tract, including taxa with fiber-degrading and butyrate-producing capabilities. Most importantly, there was little change in the absolute abundance of known mucus-degrading bacteria, although, due to the general loss of taxa, relative abundance would erroneously indicate an increase in mucus degraders. These findings underscore the importance of using quantitative methods in microbiome research, suggesting erosion of the mucus layer during fiber deprivation is due to diminished mucus production rather than overgrowth of mucus degraders.
Clinical, epidemiological, and histopathological aspects of breast cancer in female dogs at Federal Rural University of Rio de Janeiro Veterinary Hospital

Abstract This study aimed to evaluate the clinical, epidemiological, and histopathological aspects of canine breast tumors at the Federal Rural University of Rio de Janeiro Veterinary Hospital (VH-UFRRJ) between April 2017 and October 2018. The study included 137 female canine dogs with mammary neoplasia who underwent a mastectomy. The animals were evaluated using a standard form that guided anamnesis and physical examination to assess the tumor’s epidemiology, development, evolution, treatment choice, and disease prognosis. Furthermore, laboratory and imaging tests were performed on the animals to search for changes that suggested metastasis. The average age of the female dogs was 10 years, and mixed-breed dogs (33%) were the most affected, followed by poodles (21%). The inguinal (79%) and caudal abdominal (64%) breasts were the most affected. Approximately 26% of the animals were castrated, 32% had already reproduced throughout their lives, 30% had pseudocyesis, and only 8% used contraceptive methods. The majority were classified as stage I (33%) and stage III (39%) according to the Tumor-Node-Metastasis (TNM) Classification System of Malignant Tumors. In 95 female dogs, 191 nodules were histopathologically evaluated, and 62% of these animals had at least one malignant tumor. Statistically, there was a direct association between tumor size and malignancy. However, other associations, such as age at diagnosis and the degree of malignancy, were not confirmed. Therefore, it can be concluded that tumor size is an important prognostic factor, with tumors >3 cm having an approximately 70% chance of being malignant.
A modeling study of irrigation effects on global surface water and groundwater resources under a changing climate

This study investigates the effects of irrigation on global water resources by performing and analyzing Community Land Model 4.0 (CLM4) simulations driven by downscaled/bias‐corrected historical simulations and future projections from five General Circulation Models (GCMs). For each climate scenario, three sets of numerical experiments were performed: (1) a CTRL experiment in which all crops are assumed to be rainfed; (2) an IRRIG experiment in which the irrigation module is activated using surface water (SW) to feed irrigation; and (3) a PUMP experiment in which a groundwater pumping scheme coupled with the irrigation module is activated for conjunctive use of surface water and groundwater (GW) for irrigation. The parameters associated with irrigation and groundwater pumping are calibrated based on a global inventory of census‐based water use compiled by the Food and Agricultural Organization (FAO). Our results suggest that irrigation could lead to two major effects: SW (GW) depletion in regions with irrigation primarily fed by SW (GW), respectively. Furthermore, irrigation depending primarily on SW tends to have larger impacts on low‐flow than high‐flow conditions, suggesting increased vulnerability to drought. By the end of the 21st century, combined effect of increased irrigation water demand and amplified temporal‐spatial variability of water supply may lead to severe local water scarcity for irrigation. Regionally, irrigation has the potential to aggravate/alleviate climate‐induced changes of SW/GW although such effects are negligible when averaged globally. Our study highlights the need to account for irrigation effects and sources in assessing regional climate change impacts.
Angular-dependent vortex pinning mechanisms in YBa2Cu3O7 coated conductors and thin films

We compare the angular-dependent critical current density (Jc) in YBa2Cu3O7 films deposited on MgO templates grown by ion-beam-assisted deposition (IBAD), and on single-crystal substrates. We identify three angular regimes in which pinning is dominated by different types of correlated and uncorrelated defects. Those regimes are present in all cases, but their extension and characteristics are sample dependent, reflecting differences in texture and defect density. The more defective nature of the films on IBAD turns into an advantage as it results in higher Jc, demonstrating that the performance of the films on single crystals is not an upper limit for the IBAD coated conductors.
Antioxidant Activities of Optimized Enzymatic Protein Hydrolysates from Hybrid Sturgeon (Huso dauricus × Acipenser schrenckii) Prepared Using Two Proteases

ABSTRACT The objective of this work was to optimize the hydrolysis conditions of hybrid sturgeon (Huso dauricus × Acipenser schrenckii) protein using flavourzyme and compound proteinase, and to evaluate the antioxidant activity of hydrolysates. The lyophilized flavourzyme hydrolysate (FH) and compound proteinase hydrolysate (CPH) with degree of hydrolysis of 18.16% and 19.35% under optimal conditions had 85.36% and 87.24% protein content, 89.19 and 96.97 g/100 g protein total amino acid content, 92.86% and 95.12% protein solubility, and 902.47 nm and 1025.76 nm particle size, respectively. The CPH had the highest DPPH and ABTS radical scavenging activities, which were 71.04 and 66.84% with IC50 at 2.85 and 3.37 mg/mL, respectively; while the FH had higher metal-chelating activity, which was 58.37% with IC50 at 24.81 mg/mL. The obtained hydrolysates have excellent antioxidant properties and could be used as food additives and natural substitutes for synthetic antioxidants compounds, particularly in food and pharmaceuticals.
Tree network design with genetic algorithms an investigation in the locality of the pruefernumber en

When handling tree networks, a number of researchers have tried using the pruefernumber representation for encoding the network, but GAs often degraded or broke down when used on this encoding. This paper investigates the locality of the pruefernumber, which can be described as the relatedness of the phenotype (the tree) and the genotype (the pruefernumber) of trees. It is shown that the locality is highly irregular on the entire solution space. We demonstrate that for star and list networks small changes of the pruefernumber lead to small changes in the tree, whereas for all other networks the locality of the pruefernumber is low. Even worse, all areas of high locality are separated from each other by large areas of low locality. Using a GA with the pruefernumber can be useful when the good solutions tend to be a “star” or a “list”. As soon as the GA should find good solutions, which are more general trees, a degradation or even complete failure of the GA is inescapable.
Connecting a Star’s Convection Zone with its Corona

Abstract This paper discusses problems which have as their uniting theme the need to understand the coupling between a stellar convection zone and a magnetically dominated corona above it. Interest is concentrated on how the convection drives the atmosphere above, loading it with the currents that give rise to flares and other forms of coronal activity. The role of boundary conditions appears to be crucial, suggesting that a global understanding of the magnetic field system is necessary to explain what is observed in the corona. Calculations are presented which suggest that currents flowing up a flux rope return not in the immediate vicinity of the rope but rather in an alternative flux concentration located some distance away.
Studies on Philippine Melastoma (Melastomataceae)—the Rarely Collected M. laevifolium Group

Abstract. Members of the Melastoma laevifolium group in the Philippines which include the poorly known M. culionense from Culion Island and the new species M. lawrenceliaoi sp. nov. from Tawi-Tawi Island are herein taxonomically reassessed and described, respectively. Having the holotype missing/lost, M. culionense is herein lectotypified. Melastoma lawrenceliaoi is closely related to M. laevifolium from Borneo but differs by having flattened and furrowed young twigs, shorter leaves, midrib and longitudinal veins with slightly curved lanceolate scales up to ca. 0.8 mm long on the lower leaf surface, solitary flowers, shorter and grass green bracteoles, hypanthium sparsely covered with neatly appressed linear scales up to ca. 0.8 mm long, longer hypanthium lobes, ovate petals and shorter greyish anthers on the longer stamens. Taxonomic notes on M. laevifolium is herein provided too.
Teaching and Student Evaluation Tasks: Cross-Cultural Adaptation, Psychometric Properties and Measurement Invariance of Work Tasks Motivation Scale for Teachers

The present research aimed to test an Amharic version of the multi-dimensional Work Task Motivation Scale for Teachers (WTMST), which measures the five pillars of university instructors’ motivation toward teaching and student evaluation tasks based on self-determination theory (SDT). Therefore, the WTMST offers the first instrument to measure all five motivational elements, and today it is one of the most applicable instruments to assess teachers’ motivation. An Amharic version of the WTMST for teaching and student evaluation tasks was adopted and assessed in large-scale data (N=1,117). Our findings demonstrate excellent reliability and construct validity (convergent, discriminant, divergent and factorial). Besides, the results of the model comparisons provided that out of the four theoretically competing models (single-order factor, correlated factor, higher-order factor and bi-factor models), the bi-factor model was the most-fitted one used for measurement invariance across various groups. Results also suggest that the factor structure of the WTMST for both teaching and student evaluation tasks demonstrate consistency across gender (men, women), university types (research, applied, and general university), age and experience in teaching. Therefore, the WTMST for teaching and student evaluation tasks may be valid in Ethiopian higher education settings.
Recent Warming of Tropical Sea Surface Temperature and Its Relationship to the Northern Hemisphere Circulation

Analyses of the global sea surface temperature (SST) were performed to examine year to decadescale variations of SST. It is found that the tropical SST, especially in the central and eastern Pacific and in the Indian Ocean, has being increasing since the late 1970's. SST averaged in the whole tropics between 20*N and 20*S was warmer by about 0.3**. 0.4* in the 1980's than in the 1970's. Convective activity in the tropics detected by the satellite-measured outgoing longwave radiation becomes more enhanced corresponding to the recent warming of the tropical SST. The Southern Oscillation Index, which represents a strength of the tropical Walker circulation, accordingly tends to become negative after the late 1970's. The Pacific/North American teleconnection pattern with significant lowering of the geopotential height at 500 mb in the North Pacific has become dominant and persistent during winter seasons in the 1980's. It is suggested that these large atmospheric anomalies may be associated with tropical heat sources enhanced by the recent warming of the tropical SST.
Elastic and Proton-Dissociative ρ 0 Photoproduction at HERA ZEUS

Elastic and proton-dissociative ρ 0 photoproduction ( γp → ρ 0 p , γp → ρ 0 N , respec-tively, with ρ 0 → π + π − ) has been studied in ep interactions at HERA for photon-proton centre-of-mass energies in the range 50 < W < 100 GeV and for | t | < 0 . 5 GeV 2 , where t is the square of the four-momentum transfer at the proton vertex; the results on the proton-dissociative reaction are presented for masses of the dissociated proton system in the range M 2 N < 0 . 1 W 2 . For the elastic process, the π + π − invariant mass spectrum has been investigated as a function of t . As in ﬁxed target experiments, the ρ 0 resonance shape is asymmetric; this asymmetry decreases with increasing | t | , as expected in models in which the asymmetry is ascribed to the interference of resonant and non-resonant π + π − production. The cross section has been studied as a function of W ; a ﬁt to the resonant part with the form W a gives a = 0 . 16 ± 0 . 06 (stat.) +0 . 11 − 0 . 15 (syst.). The resonant part of the γp → π + π − p cross section is 11 . 2 ± 0 . 1 (stat.) +1 . 1 − 1 . 2 (syst.) µ b at h W i = 71 . 7 GeV. The t dependence of the cross section can be described by a function of the type A ρ exp ( − b ρ | t | + c ρ t 2 ) with b ρ = 10 . 9 ± 0 . 3 (stat.) +1 . 0 − 0 . 5 (syst.) GeV − 2 and c ρ = 2 . 7 ± 0 . 9 (stat.) +1 . 9 − 1 . 7 (syst.) GeV − 4 . The t dependence has also been studied as a function of W and a value of the slope of the pomeron trajectory α IP ′ = 0 . 23 ± 0 . 15 (stat.) +0 . 10 − 0 . 07 (syst.) GeV − 2 has been deduced. The ρ 0 spin density matrix elements r 0400 , r 041 − 1 and ℜ e [ r 0410 ] have been measured and found to be consistent with expectations based on s -channel helicity conservation. For proton-dissociative π + π − photoproduction in the ρ 0 mass range, the distributions of the two-pion invariant mass, W and the polar and azimuthal angles of the pions in the helicity frame are the same within errors as those for the elastic process. The t distribution has been ﬁtted to an exponential function with a slope parameter 5 . 8 ± 0 . 3 (stat.) ± 0 . 5 (syst.) GeV − 2 . The ratio of the elastic to proton-dissociative ρ 0 photoproduction cross section is 2 . 0 ± 0 . 2 (stat.) ± 0 . 7 (syst.).
Effect of Nanosilica Incorporation on Flexural Strength, Shear Bond Strength, and Color of Veneering Porcelain after Thermocycling

AIM: The focus of this research was to see how silica nanoparticles changed veneering porcelain over a zirconia core affected flexure strength, shear bond strength, and color. METHODS: A total number of 30 zirconia core veneer samples were constructed and classified according to silica nanoparticles modification of veneering porcelain into two groups: Group 1 (control group) veneering porcelain without any modification (n = 15) and Group 2 (modified group) veneering porcelain modified by silica nanoparticles (n = 15). Silica nanoparticles were added to the veneering porcelain powder at a rate of 5% by weight. Silica nanoparticles powder and veneering porcelain powder were manually crushed for about 10 min using a pestle and mortar then the mixed powder was combined with the porcelain moldings liquid to make a paste. After thermal cycling, each group was examined for flexural strength, shear bond strength, and color measurement (n = 5). Universal testing equipment was used to determine flexural and shear bond strength. The color shift was measured using a spectrophotometer. RESULTS: Flexural strength levels in the modified group (280.9 ± 29.85 Mpa) were substantially higher than in the control group (431.78 ± 22.73 Mpa). Shear bond strength values in the modified group (34.31 ± 5.6) were significantly higher than in the control group (26.97 ± 4.03). Color change was within the clinical acceptable range (1.71 ± 0.32). CONCLUSIONS: The addition of silica nanoparticles to veneering porcelain improved the flexural and shear bond strength, as well as, color change was within the clinical acceptable limits.
Quotient Equations and Integrals of Motion for Scalar Field

S.S. MoskaliukBogolyubov Institute for Theoretical PhysicsMetrolohichna Str. , 14-b, Kyiv-143, Ukraine, UA-03143e-mail: mss@bitp.kiev. uaAbstractIn this article a group-theoretical aspect of the method of dimensionalreduction is presented. Then, on the base of symmetry analysis for ananisotropic space geometrical description of dimensional reduction of equa-tion for scalar ﬁeld is given. Formula for calculating components of theenergy-momentum tensor from the variables of the ﬁeld factor-equations isderived.
Humate mining in northwestern New Mexico

Every fall since 1950, the New Mexico Geological Society (NMGS) has held an annual Fall Field Conference that explores some region of New Mexico (or surrounding states). Always well attended, these conferences provide a guidebook to participants. Besides detailed road logs, the guidebooks contain many well written, edited, and peer-reviewed geoscience papers. These books have set the national standard for geologic guidebooks and are an essential geologic reference for anyone working in or around New Mexico.
"Nodal gap" induced by the incommensurate diagonal spin density modulation in underdoped high-$T_c$ superconductors

Recently it was revealed that the whole Fermi surface is fully gapped for several families of underdoped cuprates. The existence of the finite energy gap along the -wave nodal lines (nodal gap) contrasts the common understanding of the -wave pairing symmetry, which challenges the present theories for the high- superconductors. Here we propose that the incommensurate diagonal spin-density-wave order can account for the above experimental observation. The Fermi surface and the local density of states are also studied. Our results are in good agreement with many important experiments in high- superconductors.
ASERUM BIOCHEMICAL PROFILES AND IMMUNO-STIMULATORY POTENTIALS OF Clarias gariepinus JUVENILES FED FISH MEAL CONTAINING DIFFERENT INCLUSION LEVELS OF Sesame indicum SEED MEAL

Sesame indicum L. is a class of the Pedaliaceae family of plants that contains good eatable oil, protein, mineral (calcium), and antioxidants and has been recommended as good food for ages. Beni seeds possess a nutritional content that is favour of digestibility, growth, and feed utilization among domesticated animals. The serum biochemical profiles and immunostimulatorypotentials of Clarias gariepinus juveniles fed Sesame indicum seed meal-based diets were carried out. Serum marker enzymes (ALT, AST, ALT, GGT, and LDH), serum chemistry; {glucose (GLU), total protein (TPN), bilirubin (BIL), cholesterol (CHL), albumin (ALB), creatinine (CTN), and immuno-stimulatory potentials; haemoglobin (Hb), packed cell volume (PCV), white blood cells (WBC), lymphocytes (LYM), neutrophils (NEU), monocytes (MON), eosinophil (EOS), and basophils (BAS) in C. gariepinus fed Sesame indicum seed meal-based diets were serum biochemical indices analyzed. High levels of serum marker enzymes {ALT (18.12-22.43U/L), AST (20.13-20.57U/L), ALT (18.62-22.65U/L), GGT (1.72-2.40U/L), LDH (104.35-110.01U/L)}, serum chemistry {Glucose (72.42- 75.34mg/dL), protein (7.01-7.04g/dL), bilirubin (0.44-1.52mg/dL), cholesterol (77.22-82.02mg/dL), albumin (2.46-3.65g/dL),creatinine (0.16-0.23mg/dL), and immuno-stimulatory potential (not greater than the permissible level) were observed in C. gariepinus fed S. indicum seed meal-based diets compared to those fed the control diet (DT1) only. Based on these results, the inclusion of S. indicum in the diets of C. gariepinus could therefore be saved and look promising in terms of health benefits.
Effect of minimally invasive surgery and laparotomy on wound infection and postoperative and intraoperative complications in the management of cervical cancer: A meta‐analysis

We performed a meta‐analysis to evaluate the effect of minimally invasive surgery and laparotomy on wound infection and postoperative and intraoperative complications in the management of cervical cancer. A systematic literature search up to July 2022 was performed and 10 231 subjects with cervical cancer at the baseline of the studies; 4307 of them were using the minimally invasive surgery, and 5924 were using laparotomy. Odds ratio (OR) with 95% confidence intervals (CIs) were calculated to assess the effect of minimally invasive surgery and laparotomy on wound infection and postoperative and intraoperative complications in the management of cervical cancer using the dichotomous methods with a random or fixed‐effect model. The minimally invasive surgery had significantly lower wound infection (OR, 0.20; 95% CI, 0.13–0.30, P < .001), and postoperative complications (OR, 0.48; 95% CI, 0.37–0.64, P < .001) in subjects with cervical cancer compared laparotomy. However, minimally invasive surgery compared with laparotomy in subjects with cervical cancer had no significant difference in intraoperative complications (OR, 1.04; 95% CI, 0.80–1.36, P = 0.76). The minimally invasive surgery had significantly lower wound infection, and postoperative complications however, had no significant difference in intraoperative complications in subjects with cervical cancer compared with laparotomy. The analysis of outcomes should be with caution because of the low sample size of 22 out of 41 studies in the meta‐analysis and a low number of studies in certain comparisons.