Miracle-dz/UniFAR-FTUs huggingface dataset:
Rural, Regional, Racial Disparities in Telemedicine Use During the COVID-19 Pandemic Among US Adults: 2021 National Health Interview Survey (NHIS)

Objective The primary objective of this study is to conduct a comparative analysis of telemedicine utilization patterns among adult populations residing in both rural and urban areas and evaluate the probability of telemedicine adoption among adults dwelling in both rural and urban areas amid the backdrop of the COVID-19 pandemic. Methods Our study has attained sample populations (n = 279,260, National Weighted Estimates = 2,391,188,373) through the secondary analysis of the National Health Interview Survey (NHIS) for the year 2021. We examined the relationship between the rural, regional, and racial variables using chi-square tests and binary logistic regression associated with telemedicine use in our multivariable analysis. Results Telemedicine use by population decreased with decreasing urbanization level, from 40.2% among adults living in large central metropolitan to 29.7% among adults living in rural area (p<0.0001). Regarding household income, adults with 400% or more of the federal poverty level (FPL) were significantly more likely to use telemedicine than adults with less than 100% of the FPL. Females were more likely than males to utilize telemedicine. In terms of region, adults living in the West were 1.25 times more likely to use telemedicine than adults living in the Northeast, and minority race/ethnicity groups (eg, Non-Hispanic Black, Hispanic, and other) are less likely to use the telemedicine rather than Non-Hispanic White. Conclusion Health equity is attained when all demographic groups enjoy uniform access to healthcare services, but disparities emerge when there are discernible variations in access to treatment. Considering this study’s findings, it becomes evident that the distinctions in poverty rates, median income levels, and healthcare utilization patterns across racial and regional lines may serve as indicators of potential health equity concerns.
The sensory evaluation and antimicrobial efficacy of Lactobacillus acidophilus supernatant on Salmonella enteritidis in milk

Abstract Postbiotics are metabolites derived from living probiotic bacteria like Lactobacillus strains, during the fermentation process and/or produced in pure form on laboratory scales. These compounds, depending on the type of probiotic from which they are prepared, have specific antibacterial agents such as: organic acids, bacteriocins, short‐chain fatty acids, and peptides. The objective of this study was to investigate the effect of Lactobacillus acidophilus supernatant (LAS) on the growth pattern of Salmonella enteritidis at fluctuating temperatures and the sensory evaluation of milk that contains this probiotic. Baranyi and Roberts's model determined the best‐fit curve for the microbial growth. According to mathematical equations, the highest and lowest specific growth (μ max) rates of S. enteritidis were obtained at 0.055 h−1 and 0.0059 h−1 and also highest and lowest maximum generation time (MGT) values were obtained at 20.06 h and 8.85 h, respectively. Sensory evaluation by the Triangel test reveals that LAS could not establish a significant (p > .05) adverse effect on milk perceptible. Regarding the results obtained in the present study, LAS, without causing adverse sensory change, could act as a safe food additive for the control of bacterial pathogens and reducing food waste, particularly in milk and milk‐containing food products.
Hurricane Wind Speed And Rain Rate Retrieval Algorithm For The Stepped Frequency Microwave Radiometer

This thesis presents the development and validation of the Hurricane Imaging Retrieval Algorithm (HIRA) for the measurement of oceanic surface wind speed and rain rate in hurricanes. The HIRA is designed to process airborne microwave brightness temperatures from the NOAA, Stepped Frequency Microwave Radiometer (SFMR), which routinely collects data during NOAA hurricane hunter aircraft flights. SFMR measures wind speeds and rain rates at nadir only, but HIRA will soon be integrated with an improved surface wind speed model for expanded utilization with next generation microwave hurricane imagers, such as the Hurricane Imaging Radiometer (HIRad). HIRad will expand the nadir only measurements of SFMR to allow the measurement of hurricane surface winds and rain over a wide swath Results for the validation of HIRA retrievals are presented using SFMR brightness temperature data for 22 aircraft flights in 5 hurricanes during 2003-2005. Direct comparisons with the standard NOAA SFMR empirical algorithm provided excellent results for wind speeds up to 70 m/s. and rain rates up to 50 mm/hr.
The Insertion of Threaded Acetabulum Components: Indications According to Specific Acetabulum Anatomy and Methods to Avoid Pitfalls

New-generation threaded acetabulum components have been used in total hip arthroplasty (THA) with good outcomes. We have extensively used the EcoFit® SC cup (Implantcast, Buxtehude, Germany) in our practice. In this report, we present some major complications related to the use of this implant, as well as insights regarding the surgical technique to avoid such adverse effects. Furthermore, we attempt to describe certain contraindications for using threaded cups in THA, taking into account specific patient anatomy and intraoperative acetabulum preparation. We have observed acetabulum roof and posterior wall fractures, as well as incomplete placement of the component. Ensuring the meticulous preparation of the peripheral rim of the acetabulum is crucial to prevent incomplete placement since threaded components have a larger diameter than that of the reamers used to prepare the acetabulum. Additionally, when dealing with the acetabula where the posterior or anterior walls have thinned, it is advisable to refrain from using a threaded cup to avoid the risk of intraoperative fractures caused by the torque forces exerted during implant insertion.
Prevention of Acid Mine Drainage (AMD) by using sulfur-bearing rocks for a cover layer in a dry cover system in view of the form of sulfur

Acid Mine Drainage (AMD) is one of the environmental problems caused in mining operation. The exposure of sulfide minerals in rocks to water and oxygen in the excavation process leads to AMD. The cover system has been constructed to prevent AMD in many cases in Indonesia for the availability and low-cost maintenance. Waste rocks are classified into Potentially Acid Forming (PAF), which is sulfur-bearing rocks, or Non Acid Forming (NAF) based on the results of geochemical analysis in the system. PAF is covered by NAF to prevent the contact of PAF with water and oxygen for the prevention of AMD in many cases in Indonesia. However, it is difficult to construct the cover system due to the shortage of NAF when most of waste rocks are PAF materials in the field. There are additionally varieties of PAF materials due to the content of sulfur in rocks in the field: some of them are unlikely to be the source of AMD. For the reasons, sample analysis of the waste rocks obtained in coal mines in Indonesia and the leaching test were conducted in order to discuss the use of some of PAF materials for the cover layer in such a case. The results indicated that it can be possible to use some of PAF materials in which most of sulfur compounds are readily-soluble for the cover layer instead of NAF after the reduction of the potential of acid production of rocks. Meanwhile, the rocks in which most of sulfur compounds are sulfide minerals have to be preferentially backfill in the dumping site since they can contribute to AMD for a long-term. The form of sulfur in rocks, therefore, should be taken into account to select PAF to utilize for the cover layer. This new concept of the cover system in which some of PAF materials are used for the cover layer makes the construction of the cover system without a large amount of NAF possible to prevent
Online learning during COVID-19: Key challenges and suggestions to enhance effectiveness

The COVID-19 pandemic has wreaked havoc on every aspect of society. It has caused profound disruption to the education system as governments around the world have temporarily closed educational institutions to contain the spread of the coronavirus. Face-to-face classes have been canceled and moved online, bringing about the rise of online learning that has allowed learners to continue their education. The sudden transition from face-to-face to online learning has, however, posed numerous challenges for students, teachers, administrators, and education leaders. Drawing on previously published sources, this article first attempts to explain different terms used to describe online learning. It then discusses key challenges posed by the widespread adoption of online learning during the pandemic, followed by a discussion of suggestions made by different researchers to enhance the effectiveness of online learning. The article concludes with a summary of key challenges and suggestions and brief recommendations for the broader adoption of online and blended learning in the post-COVID-19 world.
Airway and Systemic Immune Responses Following the Third COVID-19 Vaccination in COPD Patients

Introduction Booster vaccinations are required to maintain protection against COVID-19. COPD patients are at higher risk of developing severe illness following SARS-CoV-2 infection. Previous cross-sectional analysis after the second COVID-19 booster showed similar immune responses in COPD patients and controls, but pre-vaccination samples were not available. This longitudinal study evaluated systemic and airway immune responses in COPD patients using samples obtained pre- and post-third COVID-19 vaccination. Methods Twelve COPD patients were recruited, with plasma, nasal and sputum (n = 10) samples collected pre-vaccination and 4- and 14-weeks post vaccination. Samples were analyzed for anti-spike IgA and IgG and cellular immunity. The ability of plasma and nasal samples to block ACE2-spike protein interaction was assessed for Wild type, Delta, and Omicron spike variants. Results Vaccinations increased anti-spike IgG in plasma (p < 0.001), nasal (IgG p < 0.001) and sputum (p = 0.002) samples, IgA in plasma (p < 0.001) and blood cellular immunity (p = 0.001). Plasma and nasal anti-spike IgA levels correlated (rho: 0.6, p = 0.02), with similar results for IgG (rho: 0.79, p = 0.003). Post-vaccination nasal (p = 0.002) and plasma (p < 0.001) samples were less effective at blocking Omicron spike binding to ACE2 compared to the Wild type spike variant. Discussion Airway and systemic immune responses against SARS-CoV-2 increased in COPD patients following a third COVID-19 vaccination. Nasal and systemic responses in COPD patients were less effective against Omicron variant compared to previous variants.
Morphology, Anatomy and Chemical Composition of Salvia fruticosa Mill in Al-Marj (Libya)

Macro, micromorphological and chemical characteristics of Salvia fruticosa Mill, wild growing in Libya were studied. The aim of the present study is to provide new properties for the identification and description of this species. The features of leaf morphology, verticillaster number, bract, calyx, corolla, stamens, trichomes, collenchyma’s rows, vascular bundle and mesophyll structure are important characters to distinguish this species. In the study, we observe morphologically different types of glandular trichomes. The results of leaf architecture studies can provide a more accurate basis for the identification of this species. The essential oil contained cineol (43.93%), β-pinene (11,43%), α-pinene (9.53%), β-myrcene (9.08%), caryophyllene (8.75%), camphor (5.12%) and α-terpineol (4.15%).
Potential effect of opium addiction on lipid profile and blood glucose concentration in type 2 diabetic patients in Iran

ABSTRACT Background: Diabetes is one of the most common chronic diseases in the world. People believe that opium improves blood glucose and lipid profiles in these patients and controversial studies show the effect of consumption of opium in controlling these indices. Accordingly, this study aimed to compare the serum levels of blood indices such as fasting blood glucose (FBS), Hemoglobin A1c (HbA1c) and lipid profile in opium users and non-users in type ΙΙ diabetic patients. Methods: In this cross-sectional study, among type II diabetic patients referred to the Diabetes Clinic of Birjand 45 opium users and 135 non-users were selected and entered the study by the convenience sampling method. Results: The results of this study showed that the mean serum levels of FBS, HbA1c, and serum lipid profiles were not significantly different between the two groups of opium users and non-users, but the levels of triglyceride (TG) were significantly 0.18 unit higher in the opium users, compared to non-opium users. Conclusion: According to the results, the use of opium does not affect the indices of blood glucose, HbA1c and serum lipid profiles except triglyceride in diabetic patients. The general belief that opioid use reduces biochemical indices does not seem to be correct. Abbreviations: FBS: fasting blood sugar; HbA1c: Hemoglobin A1c; LDL: low-density lipoprotein; HDL: High-density lipoproteins; HDL-C: High-density lipoproteins-cholesterol; BMI: Body mass index; IQR: Inter quartile range; TG: triglyceride; TC: total cholesterol; NS: non-significant; S: significant; ATN: Acute tubular necrosis
The pine processionary moth Thaumetopoea pityocampa (Notodontidae) species complex: a phylogeny-based revision

The pine processionary moth, Thaumetopoea pityocampa, is an iconic insect in the Mediterranean culture because of its economic and medical importance and the unique traits of the life history, namely the winter feeding and the construction of conspicuous silk tents by the larvae. Its taxonomic status, however, is unclear because the type material is not available and there is confusion among the several species and subspecies described in the last centuries. In the present study, a metadata analysis of morphological and molecular data of the species in the T. pityocampa complex were considered for species delimitation, using more than 400 individuals from more than 120 geographic locations. A reconstruction of the origin of the material used for the first formal description has allowed to identify the type locality and to design a neotype. In addition, as Denis and Schiffermüller were referring to the work of Réaumur for details about the species, the description provided by Réaumur was reviewed. The results indicate that the barcode region of mitochondrial DNA is a reliable trait to separate species in most cases whereas morphological traits are not. Hybridization among taxa makes it difficult to delimit species in contact zones when mating barriers are not present. In other cases, such as the populations of Crete Island, the lack of gene flow with the mainland population may support species delimitation even when morphological traits are not conclusive. Thus, the new species Thaumetopoea cretensis is described here based on the evidence obtained from a previous study. Species delimitation based on both mitochondrial and nuclear markers allowed maintenance of three species of the complex (T. cretensis, T. pityocampa, and T. wilkinsoni) while more data are needed to determine the status of two recently described species: T. hellenica and T. mediterranea.
Exploring the impact of gamification and the Flippity tool in teaching Brazilian culture: insights and recommendations

Gamification in education makes learning engaging, motivating, and interactive, stimulating active participation and skill development through game elements. In this context, this experiential report aims to describe and reflect on the use of games as an aid in the literacy process in the early years of elementary school, and how the use of the digital tool Flippity can contribute to this process. Besides that, we conducted a bibliographic analysis on the topic to enrich the reflection. The study reveals positive outcomes of using games in children’s literacy education, fostering enjoyable learning experiences. Based on these findings, we offer six recommendations to enhance gamification in literacy teaching to promote effective learning for students.
Phytochemical investigation and antimicrobial activity from rhizomes of alocasia odora K. Koch

Alocasia odora is a common plant species in Viet Nam. A phytochemical investigation of the ethyl acetate extract (EtOAc) of A. odora rhizomes collected in Tuyen Quang province led to the isolation and determination of five compounds, including three alkaloids, alocasin A (1), hyrtiosin B (2), hyrtiosulawesine (3), one mono-phenol, p-hydroxycinamic acid (4), and one fatty acid, myristic acid (5). The chemical structures of those compounds were determined by 1D and 2D-NMR spectroscopic, MS data and compared with those reported in the literature. Antimicrobial activity against microorganisms was evaluated using the broth microdilution method, showing that alkaloids 1 - 3 exhibited antimicrobial activity against reference strains with MIC values ranging from 8 µg/mL to 128 µg/mL, in which compound 1 was the most active with MIC values calculated between 8 µg/mL and 32 µg/mL. Compound 4-5 did not display antimicrobial activity at the studied concentration, MIC > 128 µg/mL. This is the first time the antimicrobial effect of A. odora has been reported.
Shallow ice-core drilling at Mount Wrangell, Alaska

During the 2003 summer we initiated a three-year study of climate and volcanic history on Mt. Wrangell, Alaska (60°N, 144°W, 4317 m). It is being done in comparison with research on Ushkovsky Volcano (56°N, 160°E, 3903 m), Kamchatka Peninsula, Russia. Both are ice-covered, andesitic volcanoes on the north Pacific rim, at 4000 m altitude and within 6° in latitude. In June 2003 a research camp was established in the Summit Caldera of Mt. Wrangell for the purpose of ice core drilling, radio echo sounding of ice depth, and maintenance of previously established photo control points on crater rims for use in aerial photugramiuetry. A 50m ice core of high quality was obtained in sections 50 cm long, with a new drill which performed very well. It will be analyzed for δ 1 8 O and δD as well as for chemical analyses of major ions and volcanic ash traces. The core extended back to 1981 and overlapped stratigraphically with core and pit studies done from 1961 to 1982 on Mt Wrangell. The 10-m deep temperature was - 18.9 °C and was found to be higher as much as 1 °C than those observed in 1970s.
Keratosis Pilaris-like Eruption during Treatment of Chronic Myeloid Leukemia with Tyrosine Kinase Inhibitors: Literature Review and Report of a Case Related to Imatinib

The advent of tyrosine kinase inhibitors (TKIs) blocking BCR-ABL activity has revolutionized the therapeutic management of patients with chronic myeloid leukemia (CML). Adverse cutaneous reactions (ACRs) are common nonhematologic adverse events associated with the use of BCR-ABL TKIs. A characteristic pattern of eruption resembling keratosis pilaris (KP) has been described in patients treated with these drugs, especially nilotinib and dasatinib. The pathogenesis of this ACR is still unknown. This type of reaction appears to be uncommon with imatinib. Here, we report the case of an elderly patient with an asymptomatic KP-like eruption, which appeared one month after starting treatment with imatinib for CML. The case presentation is accompanied by a review of similar reactions in patients with CML treated with BCR-ABL inhibitors, attempting to make an excursus on the molecular targets of such drugs and possible mechanisms underlying this ACR.
The Relationship between Trop-2, Chemotherapeutic Drugs, and Chemoresistance

Trop-2 is a highly conserved one-pass transmembrane mammalian glycoprotein that is normally expressed in tissues such as the lung, intestines, and kidney during embryonic development. It is overexpressed in many epithelial cancers but is absent in non-epithelial tumors. Trop-2 is an intracellular calcium signal transducer that participates in the promotion of cell proliferation, migration, invasion, metastasis, and probably stemness. It also has some tumor suppressor effects. The pro-tumoral actions have been thoroughly investigated and reported. However, Trop-2’s activity in chemoresistance is less well known. We review a possible relationship between Trop-2, chemotherapy, and chemoresistance. We conclude that there is a clear role for Trop-2 in some specific chemoresistance events. On the other hand, there is no clear evidence for its participation in multidrug resistance through direct drug transport. The development of antibody conjugate drugs (ACD) centered on anti-Trop-2 monoclonal antibodies opened the gates for the treatment of some tumors resistant to classic chemotherapies. Advanced urothelial tumors and breast cancer were among the first malignancies for which these ACDs have been employed. However, there is a wide group of other tumors that may benefit from anti-Trop-2 therapy as soon as clinical trials are completed.
Bathymetric controls on very low frequency rip current motions

ABSTRACT McCarroll, R.J.; Brander, R.W. , and Turner, I.L. , 2016. Bathymetric controls on very low frequency rip current motions. In: Vila-Concejo, A. ; Bruce, E. ; Kennedy, D.M. , and McCarroll, R.J. (eds.), Proceedings of the 14th International Coastal Symposium (Sydney, Australia). Journal of Coastal Research, Special Issue, No. 75, pp. 418-422. Coconut Creek (Florida), ISSN 0749-0208. Time-averaged mean rip currents are forced by persistent gradients in dissipation over shallow bars and deep rip channels. Time-variable horizontal surfzone eddies, at the ∼10 min or very low frequency (VLF) range, are forced by stochastic wave breaking injecting vortical energy into the surfzone. Previous observations note that deep channel rips have greater variability of velocity while shallow channel rips exhibit greater variability in trajectory, this suggests a continuum of flow states that at present are poorly understood. This paper investigates the degree of bathymetric control on VLF motions illustrating how VLF motions manifest on different morphologies. Three field sites are investigated using low-pass filtered: (i) mean velocity; (ii) variable eddy velocity; (iii) directional standard deviation; and (iv) instantaneous vorticity. A VLF flow-type parameter is introduced to differentiate flow regimes, based on degree of bathymetric control. A novel classification scheme is introduced: (i) strong bathymetric control, with high mean velocities and rip cell oscillation; (ii) moderate control, with high mean velocities and variable VLF trajectories; and (iii) weak control, with low mean velocities and mobile eddies. Level of bathymetric control may be related to channel orientation, in addition to relative depth. This study improves our understanding of rip flow variability over short times frames, with implications for sediment transport and beach safety.