Miracle-dz/UniFAR-FTUs huggingface dataset:
THE EFFECT OF PROBIOTIC AND ENZYME MIXTURE CONTAINING PHYTASE ON GROWTH PERFORMANCE, CARCASS CHARACTERISTICS, MEAT QUALITY AND BIOCHEMICAL CONSTITUENTS OF PLASMA OF BROILER CHICKS FED DIFFERENT PROTEIN LEVELS

The influence of dietary protein levels and two types of pro-nutrients e.g. enzyme mixture containing phytase or probiotics on growth performance, carcass characteristics, meat quality and plasma biochemical constituents of broiler chicks was studied herein as means of improving protein utilization and decreasing feed cost. A complete randomized factorial design was conducted including two levels of crude protein 22 and 20% CP in the starting and 20 and 18% CP in the growingfinishing periods. Each CP level was fed either without or with enzyme mixture containing phytase or probiotics. Thus, there were 6 dietary experimental treatments, each one was fed to 24 one d-old unsexed broiler chicks divided equally among four replicates of 6 chicks each housed in a battery (30×35×40 cm). At the end of the experiment, 3 chicks of each treatment were slaughtered to determine carcass characteristics and meat quality traits. Furthermore, four plasma blood samples of each treatment were collected to determine some biochemical constituents. Also, nutrients digestibility and economic efficiency of treatments were also calculated. Increasing protein level significantly increased growth, decreased feed intake thus improved feed conversion ratio (FCR), protein conversion ratio (PCR) and economic efficiency. Pro-nutrients supplementation significantly increased growth, decreased feed intake and improved FCR, PCR and economic efficiency, with probiotics being more efficiently than enzyme mixture containing phytase, and this was clear in each protein level. Enzyme mixture containing phytase or probiotics significantly improved digestibility of dry matter and crude fibre. Increasing protein level significantly increased front part and decreased hind part, meanwhile protein level and /or pro-nutrients did not significantly affect chemical composition and physical characteristics of meat. Enzyme mixture containing phytase increased plasma Ca and inorganic phosphorus (iP), the later was significantly increased by probiotics supplementation, too. Plasma ALT was significantly decreased due to probiotics supplementation, showing the improvement in liver functions. In conclusion, low crude protein diet e.g. 20 and 18% in the starter and growerfinisher diets, respectively could be fed to broiler chicks when supplemented with probiotics cocktail containing Bacillus subtillis fermentation extract, Brewers yeast extract, lactic acid, citric acid, calcium propionate, sodium aluminosilicate and DLmethionine without adverse effects on growth performance and carcass quality, moreover it improved economic efficiency.
coupled Hydrodynamic Flow Focusing (cHFF) to Engineer Lipid–Polymer Nanoparticles (LiPoNs) for Multimodal Imaging and Theranostic Applications

An optimal design of nanocarriers is required to overcome the gap between synthetic and biological identity, improving the clinical translation of nanomedicine. A new generation of hybrid vehicles based on lipid–polymer coupling, obtained by Microfluidics, is proposed and validated for theranostics and multimodal imaging applications. A coupled Hydrodynamic Flow Focusing (cHFF) is exploited to control the time scales of solvent exchange and the coupling of the polymer nanoprecipitation with the lipid self-assembly simultaneously, guiding the formation of Lipid–Polymer NPs (LiPoNs). This hybrid lipid–polymeric tool is made up of core–shell structure, where a polymeric chitosan core is enveloped in a lipid bilayer, capable of co-encapsulating simultaneously Gd-DTPA and Irinotecan/Atto 633 compounds. As a result, a monodisperse population of hybrid NPs with an average size of 77 nm, with preserved structural integrity in different environmental conditions and high biocompatibility, can be used for MRI and Optical applications. Furthermore, preliminary results show the enhanced delivery and therapeutic efficacy of Irinotecan-loaded hybrid formulation against U87 MG cancers cells.
Effect of Shade on Agro-Morphological Parameters and Weed Flora of Saffron (Crocus sativus L.) Cultivation in the Semiarid Zone of Eastern Morocco

Saffron (Crocus sativus) has been an important medicinal plant since ancient times. This study aimed to seek the optimal light intensity for saffron growth by quantifying the effects of different shade levels on yield, vegetative growth, and weed development in the eastern region of Morocco. The plants were grown for 24 months in full sun (control) and 30%, 50%, and 70% shade. Overall, the results showed that shade positively affected the yield and vegetative growth parameters of saffron plants, with the highest yield (0.61 g/m2) and number of leaves (105 leaves/tuft) recorded when the plants were exposed to light shade (30%). The color of the leaves under the 70% shade levels was dark green. The results from the underground part showed that shade is positively correlated with the weight and diameter of daughter corms where the 70% shade recorded the highest values of weight (65 g) and percentage of large diameter corms (39%). As for weed density, this parameter was significantly affected by shade. The lowest weed density was recorded for the 70% shade treatment. In conclusion, 30% shade is suggested as optimal light irradiation for saffron cultivation.
EFFECT OF INFORMATION TECHNOLOGY INFRASTRUCTURE ON CUSTOMER RELATIONSHIP MANAGEMENT IN PRIVATE HOSPITALS IN KENYA

Purpose: The purpose of this study was to establish the effect of information technology infrastructure on customer relationship management in private hospitals in Kenya Materials and Methods: The study adopted descriptive survey design. It targeted 161 private hospitals which are accredited by NHIF in Kenya and which formed the unit of analysis of the study. Simple random sampling was then be used to obtain the 644 respondents. The researcher utilized a structured questionnaire with a five-point Likert scale to gather the data. The collected data was coded and entered in SPSS for further analysis. Descriptive and inferential analysis was conducted. Before inferential analysis was conducted, diagnostics tests were done. Results: The findings indicate there was a statistical and significant relationship between information technology infrastructure and customer relationship management. Therefore, the research theory was rejected and the substitute hypothesis that information technology infrastructure has a statistically significant effect on CRM in private hospital was supported. The results show that if private hospitals enhanced their technology initiatives such as interconnecting operating systems, installing human-friendly machine system and improving network and telecommunication technology, patients would be satisfied with their services and would come back or refer a friend. Unique contribution to theory, practice and policy: The study recommends that hospitals ought to enhance their CRM policies so as to deliver quality services that satisfy Information technology infrastructure can revolutionize healthcare with the right policy choices. IT can foster new human connectivity thresholds and is a powerful tool of global convergence through the cross-border provision of services and can as well provide new opportunities for the production of knowledge and skills.
Study of The Effect of Functional Endoscopic Sinus Surgery on Spirometry in Patients with Chronic Rhinosinusitis and Chronic Obstructive Lung Disease

The goal of this study is to assess the effect of functional endoscopic sinus surgery (FESS) on spirometry results in patients with chronic rhinosinusitis (CRS) and chronic obstructive lung disease. In Otorhinolaryngology and chest departments in Beni-Suef University hospital from August 2016 to February 2019, 60 patients were included in this study: 47 were asthmatic and 13 were chronic obstructive pulmonary disease (COPD) and all had chronic rhinosinusitis with nasal polypi, preoperative spirometry and computerized tomography (CT) were done. Lund-MacKay CT score system was used. After FESS by comparing results of preoperative spirometry in Forced Expiratory Volume at 1 st second percentage (FEV1%) and Forced Expiratory Volume at 1 st second/ Forced Vital Capacity percentage (FEV1/FVC%) and Lund-MacKay CT score, there was a statistical significance in improvement of FEV1% and FEV1/FVC% on 1 st and 3 rd months postoperative in both asthmatic and COPD patients and there was a statistical significance in decrease of Lund-MacKay CT score on 3 rd month postoperatively.
Renal Volume Nomogram on Computed Tomography in North Indian Population Correlated with Age, Gender and Height

Introduction: Assessment of renal size is a difficult task in view of the complex shape of kidney. Among different imaging modalities Computed Tomography (CT) and Magnetic Resonance Imaging (MRI) owing to their 3 Dimensional reconstructional ability are quite helpful in assessment of kidney size. A relationship between renal size and anthropometric parameters is an issue of interest. Aim: To assess kidney size in North Indian adult population using CT and to assess its relationship with age, sex and height. Materials and Methods: This was a cross-sectional study done over a period of two years (January 2018 to December 2019) in which a total of 300 adults aged between 20-90 years with normal renal function were enrolled. Age and sex of subjects was noted and their heights were measured. All the subjects underwent computed tomographic assessment for kidney size using 384 Slice Somatom Force, Seimens Corp. Multidetected CT machine. Contrast enhanced abdominal CT was performed to visualise the kidneys. Linear renal dimensions (length, lateral diameter, anteriorposterior diameter) were measured and renal volume was calculated using the ellipsoid volume formula. Data was analysed using Statistical Package for the Social Sciences (SPSS) version 21.0 software. Independent samples t-test, paired t-test, Analysis of Variance (ANOVA) and Pearson coefficient constants were calculated. Results: A total of 300 subjects were included, with the mean age of subjects were 41.12 years. Exactly half (50%) were males. Mean kidney size was 94.62 (95% CI: 90.27-98.97) cm3 for right side and 119.84 (95% CI=113.40-126.29) cm3 for left side. Average kidney size was 107.23 (95% CI=102.66-111.80) cm3. For both the sides, males had significantly larger kidney as compared to that of females (p-value <0.01). With increasing age, a significant decline in kidney size was observed (p-value <0.001). With increasing height, a significant increase in kidney size was observed (p-value <0.001). Height showed a significant positive correlation with both right and left side of kidney size (r=0.588, p-value <0.05). Conclusion: The present study provided the normal range for kidney size among North Indian adults using CT. The findings showed an age, gender and height dependence of kidney size in present study population.
Community‐based postural control assessment in autistic individuals indicates a similar but delayed trajectory compared to neurotypical individuals

Autistic individuals exhibit significant sensorimotor differences. Postural stability and control are foundational motor skills for successfully performing many activities of daily living. In neurotypical development, postural stability and control develop throughout childhood and adolescence. In autistic development, previous studies have focused primarily on individual age groups (e.g., childhood, adolescence, adulthood) or only controlled for age using age‐matching. Here, we examined the age trajectories of postural stability and control in autism from childhood through adolescents using standardized clinical assessments. In study 1, we tested the postural stability of autistic (n = 27) and neurotypical (n = 41) children, adolescents, and young adults aged 7–20 years during quiet standing on a force plate in three visual conditions: eyes open (EO), eyes closed (EC), and eyes open with the head in a translucent dome (Dome). Postural sway variability decreased as age increased for both groups, but autistic participants showed greater variability than neurotypical participants across age. In study 2, we tested autistic (n = 21) and neurotypical (n = 32) children and adolescents aged 7–16 years during a dynamic postural control task with nine targets. Postural control efficiency increased as age increased for both groups, but autistic participants were less efficient compared to neurotypical participants across age. Together, these results indicate that autistic individuals have a similar age trajectory for postural stability and control compared to neurotypical individuals, but have lower postural stability and control overall.
Colorectal cancer surgery in elderly patients 80 years and older: a comparison with younger age groups.

Background A reduction in complications and mortality can be observed over the last few decades among elderly patients in the early postoperative period for colorectal cancer (CRC) surgery, but long-term outcomes are largely unknown. This study aimed to investigate the long-term outcomes of elderly patients 80 years and older after CRC surgery in comparison with younger age groups. The influence of clinical, oncological, and physical parameters on outcome were retrospectively analyzed. Methods A total of 346 patients underwent CRC surgery with curative intent between January 2013 and December 2017. Patients were divided into three age groups: younger than 60 (n=47), between 60 and 79 (n=218), and 80 and older (n=81). Clinicopathological variables including comorbidity, modified frailty index, prognostic nutrition index (PNI), operative/postoperative data, and outcome including cause of death were compared among age groups. To identify factors associated with death from CRC and other causes, univariate and multivariate analyses using the Cox proportional hazards model were performed. Results Immediate postoperative morbidity of patients with Clavien-Dindo grades of III or greater (16.0%) and the 30-day mortality rate (2.5%) of patients 80 years and older were not statistically different from those of younger age groups. Long-term disease-free survival was also similar among age groups, suggesting CRC surgery provides oncological benefit to patients irrespective of age. Multivariate analysis revealed that R1 resection, advanced tumor stage, carcinoembryonic antigen (CEA) level of >5 ng/mL, undifferentiated tumor, and longer postoperative hospital stay were risk factors for CRC death. Long-term overall survival was significantly reduced in comparison to younger age groups. Seventy percent of deaths in elderly patients during follow-up were primarily from respiratory failure and cardiovascular disease. Multivariate analysis demonstrated that advanced age, frailty, low PNI, and open procedure were risk factors for other causes of mortality. Conclusions Elderly patients undergoing CRC surgery appeared to enjoy similar oncological benefits as younger age groups. Since both modified frailty index and PNI were correlated with mortality unrelated to CRC, preoperative assessment of these factors can be important for predicting outcome and selecting patients for prehabilitation.
Effects of Iron Deficiency and Its Indicators on Lymphocyte Subsets: A Study at King Fahd Hospital of the University, Saudi Arabia

Background Iron deficiency plays an important role in our body’s immunity. Several studies have shown that it is frequently associated with infections. Objective This study aimed to discover the effect of iron deficiency on immunity by demonstrating changes occurring in lymphocyte subsets among patients with an established diagnosis of iron deficiency. Methods A total of 64 iron-deficient patients and 19 healthy controls were included. Complete blood counts, serum iron, ferritin, and total iron-binding capacity were assessed. Lymphocyte subsets were evaluated by flow cytometry. Results Among iron-deficient patients, the anemic ones (Hb ≤11 g/dL) showed significantly lower absolute lymphocyte counts (p=0.013), lower relative and absolute NK-cell counts (p=0.025 and p=0.003, respectively), higher relative T-cell and CD4+-cell counts (p=0.026 and p=0.002, respectively). B cells and CD8+ T cells were not affected by any iron-deficiency indicators. Iron-deficient anemia patients showed a three- to fourfold increase in risk of having recurrent infections. Conclusion Iron deficiency has an obvious effect on lymphocyte subsets. Changes in lymphocyte subsets started mainly in response to decreased hemoglobin, rather than decreased ferritin and/or iron. Synchronously decreased hemoglobin and increased total iron-binding capacity led to absolute decreases in total lymphocytes, mainly NK cells, and relative increases in T cells, mainly the helper ones. Monitoring changes in lymphocyte subsets may be helpful in identifying patients at risk of recurrent infections.
A GAN-Based Short-Term Link Traffic Prediction Approach for Urban Road Networks Under a Parallel Learning Framework

Road link speed is often employed as an essential measure of traffic state in the operation of an urban traffic network. Not only real-time traffic demand but also signal timings and other local planning factors are major influential factors. This paper proposes a short-term traffic speed prediction approach, called PL-WGAN, for urban road networks, which is considered an important part of a novel parallel learning framework for traffic control and operation. The proposed method applies Wasserstein Generative Adversarial Nets (WGAN) for robust data-driven traffic modeling using a combination of generative neural network and discriminative neural network. The generative neural network models the road link features of the adjacent intersections and the control parameters of intersections using a hybrid graph block. In addition, the spatial-temporal relations are captured by stacking a graph convolutional network (GCN), a recurrent neural network (RNN), and an attention mechanism. A comprehensive computational experiment was carried out including comparing model prediction and computational performances with several state-of-the-art deep learning models. The proposed approach has been implemented and applied for predicting short-term link traffic speed in a large-scale urban road network in Hangzhou, China. The results suggest that it provides a scalable and effective traffic prediction solution for urban road networks.
Investigating The variations in The expression level of CEA and TIMP-1 markers in Human Colorectal Carcinoma in Egyptian Patient

Background/Aims: In this current study, Our aim is studying verification and confirmation of the use of two markers of colorectal cancer in Egyptian patients to discover the disease and diagnose it early, because the deaths associated with it are constantly increasing and very worrying, and there are previous studies, which some have reported that confirmed the high level of these markers in Blood plasma, when colon cancer occurs and some other studies have not been confirmed, and we did this study to verify their association with the disease in the presence of an increase in their level in blood plasma in Egyptian patients with the disease than healthy people or not related and these two were chosen CEA and TIMP-1 because they have found them linked to many different types of cancers and we want to work on using them in the early diagnosis of colorectal cancer to avoid death from it and improve the diagnosis in the initial stages of its occurrence so that we can quickly cure it and get rid of it forever and improve the level of survival rate when an injury occurs in the Egyptian society and It has been proven from this study that both the CEA and TIMP-1 concentration is present in the blood plasma with an increase in patients than in healthy humans. Materials and Methods: Blood samples were collected from eighty-four Egyptian patients. They were categorized into 64 patients with CRC: males 45.5% and females 54.5% with age range from 23 to 73 years (Mean ± SD: 45.8 ± 12.4 years); and 20 healthy controls: males 55% and females 45% with age range from 25 to 67 years (Mean ± SD: 43.7 ± 10.8 years). Results: A clear increase in the concentration of markers ( CEA, TIMP-1) included in the study in blood plasma in patients more than healthy with a wide and clear difference, which indicates the correlation of the increase with the presence of the disease . Conclusion: It has been verified and confirmed in this study that both markers CEA and TIMP-1 increase in the case of disease and therefore can be used significantly in detection and the diagnosis of the disease early and improve its treatment and recovery from it
Effects of Deep Rotary-Subsoiling Tillage Method on Brown Physical Properties and Maize Growth in Northeast of China

【Objective】 The feasibility of deep rotary-subsoiling tillage method in maize production was explored in northeast of China. 【Method】The designed six tillage treatments were rotary tillage(R),subsoiling tillage(S),deep rotary-subsoiling 30 cm(DRS30),deep rotary-subsoiling 50 cm(DRS50),deep rotary-subsoiling 30 cm+plastic film mulching(DRS30P),deep rotary-subsoiling 50 cm+plastic film mulching(DRS50P). The effects of different tillage methods on some soil physical properties,maize root,spring maize growth and crop yield were measured in Changtu county of Liaoning province.R and S were set as the control. 【Result】Deep rotary-subsoiling treatments could effectively break plow pan,significantly improved some soil physical properties.The soil bulk density of deep rotary-subsoiling treatments were lower than that of the control(including R and S). DRS50P treatment was the lowest and R treatment was the highest among treatments.Soil temperature and soil water content were higher in DRS50P and DRS30P treatments than other treatments.DRS50 and DRS30 treatments showed the lowest levels in soil water content at seedling stage,DRS50 and DRS30 were the higher than the control at other stages.Some soil physical properties in DRS50P and DRS30P,DRS50 and DRS30 treatments showed significant differences.Deep rotary-subsoiling treatments promoted the growth of maize root system.At jointing and milky stages,DRS50P and DRS30P treatments gained the highest amount of root number,root length,root volume and root shoot ratio,followed by DRS50 and DRS30 treatments.R treatment showed the lowest levels in the above parameters.At maturity stage,root length and root number in DRS50P and DRS30P treatments were the highest,root volume and root shoot ratio were the lower than other treatments.The differences of plant traits in DRS50P and DRS30P,DRS50 and DRS30 treatments were little.Deep rotary-subsoiling treatments promoted maize growth and development of shoot,and increased the yield of grain.DRS50P and DRS30P treatments evidently increased ear length,ear diameter,kernels per row and hundred-kernel weight.DRS50P treatment had the highest grain yield of 12 137.4 kg·hm-2,and grain yield of DRS30P treatment ranked the second places of 11 929.2 kg·hm-2.The differences between DRS50P and DRS30P showed no significant,but were significantly higher than that of other treatments.DRS50P and DRS30P treatments respectively increased yield by 23.0% and 20.8% than R treatment,by 14.1% and 12.1% than S treatment. 【Conclusion】In consideration of the comprehensive operation cost and power consumption,the DRS30P seems worth promoting.