Miracle-dz/UniFAR-FTUs huggingface dataset:
Radio-opacity of the Bones of Commonly Consumed Fish from the Red Sea

Introduction Foreign body (FB) ingestion is one of the most common complaints presenting at an emergency department (ED), with fish bone impaction being a frequent cause of presentation. Fish bones might be challenging to identify on routine radiography and ED physicians are often left in a state of uneasiness owing to the fear of complications occurring if the fish bone is not removed. Objective This study aimed to establish the factors affecting the radio-opacity of fish bones on X-ray. Materials and methods The study involved the top three fish species consumed on Saudi Arabia’s western coast. Fish bones from three specimens of each species were radiographically examined by hand-picking bones from different parts of the fish, with particular attention paid to bones that are difficult to spot. Bones were then arranged beside each other, and radiographs were taken for comparison. Inter-species and intra-species radio-opacity variation was tested. Further, the weight of each fish and method of cooking (baked vs. fried) were tested for their effect on radio-opacity. Results No significant difference in radio-opacity was found among and between different species, and the method of cooking did not alter the radio-opacity of fish bones. Significant differences in radio-opacity were noted with the difference in the diameter and size of the fish bones, which tended to be less radio-opaque in smaller-sized fish, regardless of the species. Conclusion The exact fish species and method of cooking did not alter the fish bone density on an X-ray. The size of the fish and the size of the fish bone are better predictors of higher fish bone density.
Helping Johnny to Search: Usable Encrypted Search on Webmail System

: End-to-end encryption is becoming common in messaging applications. E-mail that is the one of most popular a messaging application has several standards and systems in its encryption. However, it is hard to say that e-mail encryption has spread enough. It has been pointed out that there are usability problems in message encryption. Even though various studies on message encryption and usability have been made, there is no study discussing utility function such as searching and sorting. In this paper, the search function is focused. We aim to investigate the usability problems on encrypted search. Therefore, a method that applies encrypted search transparently is proposed at ﬁrst. The implementation of the proposed method is achieved using Google Chrome Extension for Gmail, and evaluation both performance and usability is conducted. We found that participants do not mind whether the search function is encrypted or not if both have almost identical UI and encrypted search operates at high speed.
4-[（Furan-2-ylmethylene）-amino]-1,5- dimethyl-1,2-dihyl-1,2-dihydo-pyrazol-3-one

The title compound (C16H15N3O2, Mr = 281.31) has been synthesized and characterized by elemental analysis and single-crystal X-ray diffraction. The Schiff base compound is a derivative of 4-aminoantipyrine. As expected, the molecular structure adopts a trans configuration about the C=N double bond. It crystallizes in the monoclinic system, space group P21/c with a = 11.150(3), b = 9.906(3), c = 13.624(4) ? , β = 106.360(4)°, V = 1443.9(7) ? 3, Z = 4, Dc = 1.294 g/cm3, F(000) = 592, μ(MoKα) = 0.088 mm-1, R = 0.0577 and wR = 0.1214. Of the 5766 total reflections, 2540 were unique. In the molecule there exist two different planes of pyrazoline and O(2)～C(10) phenyl ring, which are appro- ximately coplanar (r.m.s. de deviation from the combined mean plane is 0026 ? ) with the dihedral angle between them of 6.3°.
Effects of Breast Cancer Stem Cell Extract Primed Dendritic Cell Transplantation on Breast Cancer Tumor Murine Models

Cancer stem cells are considered as an origin of cancer. Cancer stem cells can cause tumors in mice models. Recent studies proved the efficacy of some promising therapies to treat cancers. Dendritic cell (DC) therapy is one of the best promising therapies to treat cancer. In recent years, DC therapy is performed by using primed cancer cell antigens of DC to immune organism body. This research aims to combine DC therapy with cancer stem cell antigen for treating breast cancer in murine models. DCs were derived from mouse bone marrow monocytes. Then they were primed with the breast cancer cell antigen prior to employ into the tumor mice model. This was performed to determine whether the DCs would capture and eventually migrate, be present in the spleen and present the cancer antigens to autologous CD8 T cells; induce the activation of the CTL response. The existence of tumors in mice was evaluated after 15-60 days from transplantation. The results showed that 40% mice of the experimental group, with injected breast cancer stem cell antigen loaded DCs, got tumors after 18 transplantation days. But in control group 100% mice got tumors after 15 transplantation days. It is also noticed that transplanted DCs could migrate into spleen, stimulate CD8 T cells and CD45 T cells proliferation. Specially, the ratio of CD8 T cells strongly increased in comparison to control or normal mice. These results are important and provides most required initial platform to do further experiment. Results of this study also established a promising novel targeting therapy for cancer, especially for breast cancer. Research Article
Profile of systemic sclerosis and associated renal involvement

Background: Systemic sclerosis (SSc) patients are encountered in all parts of the world. Few Indian studies are found in the literature on this connective tissue disorder of unknown etiology. The spectrum of sclerodermatous diseases comprises a wide variety of clinical entities. Renal involvement is not common in Indian patients when compared to western patient′s in spite of the kidney being commonly affected in scleroderma due to vascular changes. Aim and Objective: To primarily study the prevalence of renal involvement in SSc and to correlate it with high-sensitivity C-reactive protein (hsCRP) over a period of 1 year in a tertiary care hospital in North-East India. Materials and Methods: A total of 38 consecutive scleroderma patients of both sexes, diagnosed by established criteria, were examined, and hsCRP was estimated in all. Evaluation for nephropathy by biochemical tests and sonography were carried out. Relevant clinical/biochemical examinations were carried out. Results: SSc was 3 times more common in mostly in middle aged females. About 50% presented within 1 year of disease onset. Renal involvement was uncommon (18%) and hsCRP was detected in 26%. Conclusion: SSc with nephropathy, not renal crisis, presents early and hsCRP is a good marker for the same.
Outcome of cord-blood transplantation from related and unrelated donors

Background Cord-blood banks have increased the use of cord-blood transplantation in patients with hematologic disorders. We have established a registry containing information on the outcome of cord-blood transplantation. Methods We sent questionnaires to 45 transplantation centers for information on patients receiving cord-blood transplants from 1988 to 1996. Reports on 143 transplantations, performed at 45 centers, were studied, and the responses were analyzed separately according to whether the donor was related or unrelated to the recipient. Results Among 78 recipients of cord blood from related donors, the Kaplan–Meier estimate of survival at one year was 63 percent. Younger age, lower weight, transplants from HLA-identical donors, and cytomegalovirus-negative serologic results in the recipient were favorable prognostic factors. Graft-versus-host disease of at least grade II occurred at estimated rates of 9 percent in 60 recipients of HLA-matched cord blood and 50 percent in 18 recipients of HLA-misma.
Epidemiologic study of osteoarthritis of the knee

In view of possible involvement of susceptible kind, degree or mode of living in the onset of osteoarthritis of the knee, we examined by questioning 104 patients with primary osteoarthritis of the knee for their occupations, modes of living, etc. before the onset.The results revealed obesity as the most responsible factor, but not the causal predominance of hard labors. Acute onset and night pain have been experienced by 30% and more than 50% of the patients, respectively.These results suggested progressive narrowing of articular fissures, on one hand and bone necrosis preceeded by sudden bone destruction leading to rapid deformity, on the other.
Utilization of Molecular Testing in Thyroid Cytology: A Concrete Aid? New Insights

Thyroid nodules are a common finding in the general population. The differential diagnoses of these lesions encompass numerous entities, both nonneoplastic and neoplastic. Fine-needle aspiration cytology is the most important diagnostic tool for evaluating thyroid lesions. It has found worldwide application because of its simplicity, safety, and costeffectiveness, and its essential role is mainly focused on the discrimination between benign andmalignant neoplasms. Increasing knowledge of molecular mechanisms of thyroid cancer, combined with an inability to definitively characterize a proportion of cases cytologically, has encouraged research into and clinical utilization of molecular techniques on fine-needle aspiration cytology samples. In particular, BRAF, RET/PTC, or RAS alterations are found inmore than 70% of papillary thyroid carcinomas, and some of them are associated with more aggressive tumor behavior. Furthermore, there is evidence of correlation ofBRAFmutationswith extrathyroidal extension, advanced tumor stage, and nodal or, less frequently, distant metastases. We believe that molecular testing can contribute to patient management, as an ancillary tool, in selected thyroid cases. However, molecular studies should not be ordered indiscriminately as a reflex test, and their results must not replace cytologic interpretation and clinical judgment.
Multivariate logistic regression analysis of risk factors for demodex infection in college students

AIM: To probe into the risk factors for demodex infection in college students for the prevention and treatment of it.METHODS: The influential factors of demodex infection were tested in some college students of Grade Ⅰ-Ⅳ in Luoyang city in 2004 by the methods of transparent adhesive paste,questionnaire and logistic regression analysis.RESULTS: The positive demodex infection rate of the college students was 24.85%(84/338) and the multivariate logistic regression analysis showed that the main factors causing demodex infection in college students were related to injury in face,annual family income per capita,habitual use of bath tools,types of soap chosen in face washing and their majors.CONCLUSION: The demodex infection in college students is closely related to their skin conditions,and social and behavioral factors.
Biology of mosquitoes.

日本には約110種の蚊が産する。 その中で医学的に重要なのは, 幼虫(ボウフラ)が人里近くの水域に発生し, 雌成虫がヒトから好んで吸血する種である。 西日本ではアカイエカ(南西諸島ではネッタイイエカにおきかわる), チカイエカ, コガタアカイエカ, ヒトスジシマカなどが最も重要である。 これらの種は生態がことなるので, その被害に対する効果的対策もことなる。 雌成虫が吸血源となる動物を発見して完了するまでの過程は複雑で, わかつていない点もある。
1-Propyl-1H-indole-2,3-dione

In the title compound, C11H11NO2, the 1H-indole-2,3-dione unit is essentially planar, with an r.m.s. deviation of 0.0387 (13) A. This plane makes a dihedral angle of 72.19 (17)° with the plane of the propyl substituent. In the crystal, chains propagating along the b axis are formed through C—H⋯O hydrogen bonds.
Somatostatin immunoreactivity in bone and joint tissues

USING immunoelectron microscopy we have investigated the presence of somatostatin in normal bone and joint tissues. We observed somatostatin labeling in the myelinated nerve fibers of the periosteum, the bone marrow cells and in the mature bone matrix but only slightly in the synovial cells. Quantification of somatostatin in bone tissue by radioimmunoassay showed highest levels in bone marrow followed by periosteum and cortical bone. These findings suggest a role for somatostatin in bone and joint physiology.
Carbapenem resistance in clinically significant Non fermenting gram negative bacilli

BACKGROUND/OBJECTIVES: The growing increase in the rates of antibiotic resistance is a major cause for concern in both non-fermenting bacilli . β-lactams have been the mainstay of treatment for serious infections, and the most active of these are the carbapenems. Acquired metallo-β-lactamases (MBL) have recently emerged as one of the most worrisome resistance mechanisms owing to their capacity to hydrolyze all β-lactams, including carbapenems. We have undertaken this study to ascertain the prevalence of MBL-producing non-fermenting bacilli. MATERIALS AND METHODS: The study included 93 isolates of NFGNB from Blood, endotracheal aspirates, sputum, urine, urinary catheter tip & pus between January 2012- January 2013. Antibiotic susceptibility to antibiotics was done by Modified Kirby Bauer method. All the isolates with a zone size ≤19mm for imipenem were included in our study to detect the presence of MBL by Imipenem-EDTA double-disc synergy test (DDST). Imipenem resistant, non MBL isolates were tested by Modified Hodge test & Amp C β lactamases. RESULTS: Of the 93 imipenem resistant NFGNB, 27(29.03%) were Pseudomonas spp. ,66(70.96%) were Acinetobacter spp.Among them, 10(37.03%) Pseudomonas spp. and seven (10.60%) Acinetobacter spp. were MBL positive by Imipenem EDTA double-disc synergy test (DDST). Five (8.40%) Acinetobacter spp. were Amp C positive and one (5.88%)strain of Pseudomonas showed positive Modified hodge test. CONCLUSION: MBL production is an important mechanism of carbapenem resistance among Pseudomonas spp. but not among Acinetobacter spp. Carbapenemases other than MBL may be responsible for carbapenem resistance in NFGNB.
Antioxidant Capacity and Metal Content of Physalis Peruviana L. Fruit Sold in Markets

1 Ayşe Eken1, Burcu Ünlü-Endirlik1, Ayşe Baldemir2, Selen İlgün2, Buğra Soykut3, Onur Erdem3, Cemal Akay3 1Erciyes University, Faculty of Pharmacy, Department of Pharmaceutical Toxicology, Kayseri, 2Erciyes University, Faculty of Pharmacy, Department of Pharmaceutical Botanic, Kayseri, 3Gulhane Military Medical Academy, Department of Pharmaceutical Toxicology, Ankara, Turkey Antioksidan Aktivite ve Metal İçerik / Antioxidant Activity and Metal Content Antioxidant Capacity and Metal Content of Physalis peruviana L. Fruit Sold in Markets
Research paper Indices of non-specific immunity: an element of natural immunity in rabbits infected with RHD (rabbit haemorrhagic disease) virus

The paper describes non-specific immunity mediated by parameters of cell and humoral immunity in rabbits experimentally infected with seven haemagglutinating strains of the rabbit haemorrhagic dis ease (RHD) virus, including one which is an antigenic variant of RHDV, originating from various Euro pean countries and with a different isolation time. In addition to the studies performed earlier on dif ferent strains of RHDV, this paper also shows that the immunological differences between the strains may be the core of the existence of immunotypes among RHDV.
Rhinopharyngeal Predictors of Snoring Among Adult African Patients

Rhinopharyngeal Predictors of Snoring Among Adult African Patients Purpose: This study purposed to examine structural anomalies in the upper airways, predominantly nose and pharynx, among an adult African sample and to determine these anomalies as possible predictors of habitual snoring. Patients and Methods: Consecutive adult patients that attended an ENT clinic were recruited into the study. Information obtained included socio-demographics and Berlin questionnaire was used to obtain information about snoring. Results: Male patients constituted 56.4% of total of 195 study subjects; mean age was 43.5 ± 15.6 years (range 20-79 years). 92 (47.2%) of subjects had tertiary education, 116 (59.5%) were married. 25(12.9%) had BMI >30.0 (Mean ± SD; 24.1 ± 4.6 kg/m2). 36 patients (18.5%) were habitual snorers. Statistically significant differences were observed at p< 0.05 between non-habitual and habitual snorers in the nasal findings, namely structural abnormalities of nasal pyramid (5.0 Vs 16.7%) and engorgement of nasal turbinates (32.1 Vs 61.1%).
ASSOCIATION OF MENOPAUSE WITH INFLAMMATION-SENSITIVE PROTEIN THE C-REACTIVE PROTEIN AMONG THE INDIAN WOMEN

BACKGROUND: The changes during menopause are associated with cardiovascular risk factors. Since inflammation is believed to have a role in the pathogenesis of cardiovascular events, measurement of markers of inflammation like high sensitivity C - reactive protein hsCRP has been proposed as a method to improve the prediction of the risk of these events. AIMS: The aim of the study was to look at the association of menopause with the inflammatory marker hsCRP, in the pathogenesis of cardiovascular events in urban south Indian menopausal women. SETTING & DESIGN: 30 pre-menopausal women as a control & 30 post-menopausal women as a subject were, taken from the Medicine OPD, Medical camps, and staff from Dr.B. R.Ambedkar Medical College Hospital and employees from HMT watch factory. Inclusion criteria: Normal healthy women & women who had undergone surgical menopause. Exclusion criteria: women with a history of chronic infections like liver disease, rheumatoid disease, jaundice, women on oral contraceptives and hormone therapy. Ethical approval was obtained, subjects were briefed about the study protocol and tests, and a written consent was taken. METHODS AND MATERIAL: Anthropometry measurements (Height, Weight, Waist/Hip ratio (WHR), Body Mass index (BMI)), CARDIOVASCULAR PARAMETERS: Systolic blood pressure (SBP)and Diastolic blood pressure (DBP), & BIOCHEMICAL PARAMETERS: Hemoglobin (Hbgm. %), Total Leucocyte Count (TLC), Differential Count (DC), hsCRP was estimated and compared for 30 premenopausal women &30 postmenopausal women. STATISTICAL ANALYSIS: Chi-square and Fisher exact test, Student t test done using SPSS 11.0 and Systat 8.0, Excel used to generate graphs, tables. RESULTS: Mean ±SD (0.68±1.32mg/L) of hsCRP in post-menopausal women was double the Mean± SD (0.34±0.85mg/L) of hsCRP in pre-menopausal women. The post-menopausal women had an elevated hsCRP (>1mg/L) compared to the premenopausal women but not statistically significant. CONCLUSION: hsCRP is increased in post-
Treatment of Diffuse Large B-cell Lymphoma

Abstract Diffuse large B-cell lymphoma (DLBCL), the most common subtype of non–Hodgkin lymphoma, usually presents in older adults with slightly increased incidence in males. Untreated, it has an aggressive course, but a remarkable increase in cure rates has resulted from combination chemoimmunotherapy, combining rituximab with chemotherapy regimens like cyclophosphamide, doxorubicin, vincristine, and prednisone. With chemoimmunotherapy, increasing dose intensity or administration of more than 6 cycles does not seem to improve results significantly. The International Prognostic Index remains prognostic, and although gene expression profiling can identify subgroups with differing prognoses, they have yet to determine treatment choices in clinical practice. In human immunodeficiency virus–associated DLBCL, rituximab plus infusional etoposide, prednisone, vincristine, cyclophosphamide, and doxorubicin seems to improve event-free and overall survival. More than 30% of DLBCL cases will ultimately relapse, requiring high-dose therapy with autologous stem cell transplantation. Newer agents targeting specific molecular pathways involved in pathogenesis are being studied in the maintenance and relapsed settings.
Assessing Symptoms Experienced by Patients With Cancer: Occurrence, Intensity, Distress, Interference, and Frequency

Patients with cancer experience multiple symptoms during their disease trajectory, all of which have the potential to cause significant distress and interference with patient quality of life. In order to adequately manage cancer-related symptoms, nurses caring for patients with cancer need to fully understand each patient’s symptom experience. The purpose of this study was to identify the symptom profile of patients being treated for cancer and to validate a new symptom assessment tool for use with persons with cancer. A sample of 234 sequential patients with a variety of cancers was accrued over 18 months in a community medical center and a regional cancer center. Consenting patients completed the newly developed Cancer Symptom Scale (CSS), the Multidimensional Quality of Life–Cancer scale, and a demographic data form. A subset of patients completed the CSS a second time with a short delay. Descriptive statistics were used to report the symptom data, and Pearson correlations and Cronbach’s &agr; were used to evaluate the validity and reliability. The sample had slightly more women (55.6%) than men and was predominantly white (82.9%) and married (63.2%). The most common types of cancer reported were leukemia, breast, lymphoma, and colorectal cancer. The mean age of the sample was 60.4 years. Fatigue and feeling drowsy affected more than half of the sample. Feeling irritable (mean, 7.3), having problems with sex (mean, 6.6), and sweats (mean, 6.3) had the highest intensity mean scores, whereas feeling irritable (mean, 6.7) and diarrhea (mean, 6.4) caused the most distress. Most frequently occurring symptoms were problems with urination (mean, 6.9) and problems with sex (mean, 6.9). Symptoms causing the most interference with life were diarrhea (mean, 6.0) and feeling irritable (mean, 5.7). Correlation of CSS subscales with the Multidimensional Quality of Life–Cancer scale (r = −0.34 to −0.56; P = .000) at the hypothesized level supported construct validity. Test-retest reliability (r = 0.74-0.81) and internal consistency (&agr; = .73-.74) were excellent. Patients have multiple symptoms that are intense, distressing, and frequent and cause interference with their lives, and all have an impact on the overall quality of their lives. Thus, nurses should use comprehensive and validated tools to assess these multiple symptoms in order to be able to manage them. The CSS is a valid and reliable tool that is useful in assessing multiple dimensions of multiple symptoms in patients with cancer. Further studies of its validity and reliability are warranted.
The Effect Of Health Insurance On Intensive Care Mortality And Procedural Utilization

ATS 2010, NEW ORLEANS— Adult patients without health insurance admitted to intensive care units (ICUs) in Pennsylvania hospitals are at a 21 percent increased risk of death compared to similar patients with private insurance, according to researchers from the University of Pennsylvania. The difference in mortality risk was not explained by patient characteristics or differences in care at the hospital level, suggesting that uninsured patients might receive poorer quality care.
Modification of Gloidblatt 2K1C Hypertension Model in Rats

Objective To expand laboratory investigation of hypertension and study a new method for establishing renovascilar hypertensive rat model.Methods The acupuncture needle and silkgature were used to instead of clip to narrow the renal artery of rats.Results A success rate of 86% was got in our experiment.The obviously elevated SBP in rats were showed two weeks after operation respectively.Conclusion This modified methods is feasible and with a higher successful rate and can be used to study hypertension further.