Miracle-dz/UniFAR-FTUs huggingface dataset:
The “War” Concept in Russian and Chinese Socio-Cultural Environment

The main idea of the article is to analyze the concept of war in Russian and Chinese sociocultures, combining methods of linguo-cognitive and psycholinguistic approaches. The concept of war, on the one hand, is studied in terms of its linguistic manifestation with the help of cognitive-definitive analysis, and on the other hand, we attempt to examine the perception of this concept in the native speakers consciousness via psycholinguistic experiment. This technique allows us to consider the language manifestation of the studied concept, that is, to draw a conclusion about the linguistic worldview, and at the same time compare the main features of the “war” concept with the idea of a war in the minds of native speakers, that is, to draw a conclusion about the cognitive worldview. Studying the “war” concept allows us to fully understand the attitude of different peoples towards life, death and the principles of historical development. The study showed that the attitude of Russian and Chinese native speakers to the issues of war and peace is quite different: for Chinese culture, the dominant is materialistic consequences from the warfare and the image of the enemy, and for the Russian – the spiritual sufferings that war brings and the idea of the war as a craft.
“Soft” Factors in Pandemic Response: Comparative Intercountry Analysis

The article discusses the challenges of the COVID-19 pandemic response that has engulfed most countries, highlights and analyses the response strategies adopted by governments Using the example of the United States, Russia, Great Britain, Spain, Italy, Germany, Japan and China, the authors have analysed the adopted restrictive regimes, models of enforcement to comply with them, schemes and tools to support the economy According to open sources, the authors estimated the duration and severity of the restrictive regimes for economic and social activity, the severity of punishments for violations of restrictive regimes, the scale of assistance to the population and business, and compliance with restrictive regimes The article pays a special attention to identifying the role of “soft” factors, such as trust and national culture, in the implementation of the pandemic response policy The authors used the index of ethnic fractionalization to characterize the homogeneity of society The article confirms that more collectivist, long-term and less masculine cultures tend to strictly comply with restrictive regimes, but the penalties imposed in countries with such a cultural code have been more severe The analysis showed that in countries with a more individualized and masculine culture, large packages of support for the population and business were allocated with a moderate severity of punishment for non-compliance with restrictions In these countries, the tension and discontent of the population, which had accumulated during the period of the restrictive regimes, became more pronounced The results obtained give grounds to assert that “soft” factors play an important role in shaping the policy of responding to the threat of a pandemic;the strategies chosen by countries in an explicit or implicit form reflect national, cultural and institutional characteristics © Siberian Federal University All rights reserved
Short-and-Long-Term Outcomes after Coronary Rotational Atherectomy in Patients Treated with Trans-Catheter Aortic Valve Implantation

Background. Coronary artery disease (CAD) is a common finding among patients undergoing trans-catheter aortic valve implantation (TAVI), who often present severely calcified coronary lesions. Evidence is scarce about the use of rotational atherectomy (RA) in this setting, in particular regarding long-term outcome. Methods. RA was performed on severely calcified coronary lesions concomitant with TAVI in a consecutive series of patients treated between 2010 and 2020. Immediate and long-term clinical outcomes are reported. Results. A concomitant CAD (coronary stenosis visually > 50%) was observed in 402/845 (47.6%) consecutive patients undergoing TAVI at the University Hospital of Verona. Angioplasty was performed in 104 patients (12.3%). Among these, 19 patients (18.3%, 20 coronary arteries), were treated with RA after TAVI: 10 after implantation of a balloon-expandable trans-catheter valve and 9 after a self-expandable valve. All procedures were successful. Hypotension occurred in 3 patients (15.8%), with rapid recovery after the procedure; CI-AKI (contrast-induced acute kidney injury) in 3 patients (15.8%), of which two recovered within discharge. At a median follow-up of 21.5 months (Q1–3: 6–36) event free survival was 83.3%. Only one patient suffered a target vessel failure >2 years after RA. Neither stroke nor peri-procedural infarctions were detected. Conclusions. RA concomitant with TAVI was feasible and safe in patients treated with implantation of either self-expandable, or balloon-expandable trans-catheter aortic valves. Long-term clinical events related to the coronary procedure were extremely infrequent and the survival rate at median follow-up of 21.5 months was 83.3%.
Fast Softmax Sampling for Deep Neural Networks

The softmax function has been widely popularized due to its frequent use in neural networks. It features a linear computation time that can dominate training time if the output space is very large. This project explores the use of kmeans clustering and uniform sampling to approximate the softmax function and achieve O( √ N) run time. We additionally present experiments varying the number of clusters and update frequency of the data structure, showing that the softmax approximation has potential to provide a significant reduction to complexity.
Media Violence and Children's ADHD-Related Behaviors: A Genetic Susceptibility Perspective

This study examined the relationship between media violence exposure and Attention-deficit/hyperactivity disorder (ADHD)-related behaviors. Using survey (parent-reported) and genetic data of 1,612 Dutch children (aged 5 to 9 years), we examined genetic disposition as a possible cause of individual differences in children's use of and susceptibility to media violence. The gene variant of interest was the 5-HTTLPR polymorphism, which has been associated with ADHD-related behaviors in previous research. Results showed that the "long" variant of the gene polymorphism was related to greater violent media use, which in turn was related to more ADHD-related behaviors. The 5-HTTLPR genotype did not moderate the effect of media violence on ADHD-related behaviors. This study provides insight into the role of genetic factors in media effects.
ANALYSING INTENTION AND ACTION IN MOBILE BANKING SERVICES

Technological advances at the level of mobile devices are transforming the world. Banking users are able to conduct banking services at any place, and at any time, with m-banking. The purpose of this research is to analyse intention and action in m-banking services. A research model was developed and PLS was used to test the causalities in the proposed model. Our proposal extends the existing models with an assessment of the actual usage of m-banking and of how behavioural intention translates into action. This study found that the main determinants of behavioural intention for m-banking are social influence and relative advantage. Furthermore, perceived risk, lack of information and usage barriers have a negative effect on m-banking behavioural intention. Perceived risks, e-banking use, and behaviour intention are found to be significant antecedents of m-banking use. Gender has a positive and significant influence on m-banking usage, but not on the construction of behavioural intention. Classification- JEL:
The EnergyKids Pilot Study: Comparing Energy Balance of Primary School Children during School and Summer Camp

Children’s energy requirements may vary during school and summer camp days. To evaluate energy balance during these two periods, seventy-eight children (45% females, 8–10 years) living in Parma, Italy, were enrolled in this observational study. Participants completed a 3-day food diary and wore an activity tracker for three consecutive days during a school- and a summer camp-week to estimate energy intake (EI) and energy expenditure (TEE). Height and body weight were measured at the beginning of each period to define children’s weight status. BMI and EI (school: 1692 ± 265 kcal/day; summer camp: 1738 ± 262 kcal/day) were similar during both periods. Both physical activity and TEE (summer camp: 1948 ± 312; school: 1704 ± 263 kcal/day) were higher during summer camp compared to school time. Therefore, energy balance was more negative during summer camp (−209 ± 366 kcal/day) compared to school time (−12 ± 331 kcal/day). Similar results were observed when males and females were analyzed separately but, comparing the sexes, males had a higher TEE and a more negative energy balance than females, during both periods. The results strongly suggest that an accurate evaluation of children’s energy balance, that considers both diet and physical activity, is needed when planning adequate diets for different situations.
Dislocation-induced superfluidity in a model supersolid

Motivated by recent experiments on the supersolid behavior of $^4$He, we study the effect of an edge dislocation in promoting superfluidity in a Bose crystal. Using Landau theory, we couple the elastic strain field of the dislocation to the superfluid density, and use a linear analysis to show that superfluidity nucleates on the dislocation before occurring in the bulk of the solid. Moving beyond the linear analysis, we develop a systematic perturbation theory in the weakly nonlinear regime, and use this method to integrate out transverse degrees of freedom and derive a one-dimensional Landau equation for the superfluid order parameter. We then extend our analysis to a network of dislocation lines, and derive an XY model for the dislocation network by integrating over fluctuations in the order parameter. Our results show that the ordering temperature for the network has a sensitive dependence on the dislocation density, consistent with numerous experiments that find a clear connection between the sample quality and the supersolid response.
Cell-based therapy in soft tissue sports injuries of the knee: a systematic review

ABSTRACT Introduction An ever-increasing number of clinics are offering purportedly ‘regenerative’ stem-cell treatments, although cell-based therapies may not primarily act as stem cells and have shown the ability to regenerate end-target tissues in some clinical studies only. We aim to systematically review the evidence for their use in soft-tissue sports injuries of the knee. Areas covered A search for articles pertaining to the use of preparations of, or containing, mesenchymal stem cells (MSCs) in human subjects in sports knee injuries yielded 14 relevant results for inclusion after screening: 7 used cultured MSCs, 5 bone marrow concentrate (BMC), and the remaining 2 evaluated stromal vascular fraction (SVF) and tenocyte-like-cells. Most studies were level 3 or lower (n = 9). Expert opinion There is insufficient high-quality evidence for the use of cell-based therapies that demonstrates either ligamentous or tendinous healing, meniscal volume restoration, or post-traumatic osteoarthritis amelioration/regression. Methods of cell harvesting, preparation, and application are highly heterogenous. Efforts should be directed toward standardization of protocols and their reporting, starting with more basic scientific investigations of MSCs and their niche, as well as rigorous, large clinical RCTs adhering to the reporting principles set out by recent expert consensus.
Agressivity in Adolescence and its Connection to Attachment

Aim: The present research is to explore the manifestation of aggressive behaviors in the years of adolescence and its relation to the type of attachment a with caregivers such as the mother and father, starting from the teenage point of view. The study was conducted during the 2016-2017 in 6 high schools of the city of Tirana. The sample included 693 teenagers aged 16-20 years old. We used the Parent’s Attachment Inventory (IPPA) (Armsden, Greenberg, 1987) that consists of 50 questions and the Questionnaire on Aggression (Buss, Perry, 1992) with 12 Likert-type questions exploring four dimensions of aggressiveness. Results: The study revealed that it is of great importance in the way of communication with parents and the connection with the emergence of some aggressive behaviors. There are obvious differences between males and females regarding aggressive behavior. Conclusion: We could refer that the linkage of parental figures with two forms of aggression emphasizes the significance of creating safe communication bridges throughout their development as a basis for adaptation with a positive approach to the environment.
Cyclin-dependent Kinase 1 and Aurora Kinase choreograph mitotic storage and redistribution of a growth factor receptor

Endosomal trafficking of receptors and associated proteins plays a critical role in signal processing. Until recently, it was thought that trafficking was shut down during cell division. Thus, remarkably, the regulation of trafficking during division remains poorly characterized. Here we delineate the role of mitotic kinases in receptor trafficking during asymmetric division. Targeted perturbations reveal that Cyclin-dependent Kinase 1 (CDK1) and Aurora Kinase promote storage of Fibroblast Growth Factor Receptors (FGFRs) by suppressing endosomal degradation and recycling pathways. As cells progress through metaphase, loss of CDK1 activity permits differential degradation and targeted recycling of stored receptors, leading to asymmetric induction. Mitotic receptor storage, as delineated in this study, may facilitate rapid reestablishment of signaling competence in nascent daughter cells. However, mutations that limit or enhance the release of stored signaling components could alter daughter cell fate or behavior thereby promoting oncogenesis.
Hyperandrogenism by Liquid Chromatography Tandem Mass Spectrometry in PCOS: Focus on Testosterone and Androstenedione

The identification of hyperandrogenism in polycystic ovary syndrome (PCOS) is concerning because of the poor accuracy of the androgen immunoassays (IA) and controversies regarding which androgens should be measured. The aim of our study was to evaluate the impact of the assessment of testosterone (T) and androstenedione (A) by liquid chromatography in tandem with mass spectrometry (LC/MS-MS), in the diagnosis of PCOS. We evaluated 131 patients referred for suspected PCOS. Fourteen patients in total were excluded, some because of other diagnosis (n = 7) or incomplete diagnostic workup (n = 7). We measured T and A both by IA and LC-MS/MS in the 117 subjects included. We calculated free T (fT) by the Vermeulen formula and recorded clinical and metabolic data. 73 healthy females served as controls to derive immunoassays (IA) and LC-MS/MS reference intervals for T, fT and A. PCOS was confirmed in 90 subjects by IA and in 93 (+3.3%) by LC-MS/MS. The prevalence of biochemical hyperandrogenism in PCOS by LC-MS/MS increased from 81.7% to 89.2% if A was also considered. The most frequently elevated androgens were fT (73.1%) and A (64.5%) and they had similar levels of accuracy in differentiating PCOS and controls (0.34 ng/dL, Sn 91% Sp 89%; 1.16 ng/mL, Sn 91% Sp 88%, respectively). Free testosterone correlated with body mass index (BMI), homeostatic model assessment (HOMA)-index, glycated hemoglobin (HbA1c), and sex-binding globulin (SHBG). The results confirm that LC-MS/MS is slightly more sensitive than IA in the diagnosis of PCOS with LC-MS/MS detecting higher levels of fT and A. Moreover, assessment of fT and A by LC-MS/MS had a similar level of accuracy in discriminating between PCOs and control subjects. Lastly, fT by LC-MS/MS correlates with adverse metabolic parameters.
Dynamics and competition of CRISPR–Cas9 ribonucleoproteins and AAV donor-mediated NHEJ, MMEJ and HDR editing

Abstract Investigations of CRISPR gene knockout editing profiles have contributed to enhanced precision of editing outcomes. However, for homology-directed repair (HDR) in particular, the editing dynamics and patterns in clinically relevant cells, such as human iPSCs and primary T cells, are poorly understood. Here, we explore the editing dynamics and DNA repair profiles after the delivery of Cas9-guide RNA ribonucleoprotein (RNP) with or without the adeno-associated virus serotype 6 (AAV6) as HDR donors in four cell types. We show that editing profiles have distinct differences among cell lines. We also reveal the kinetics of HDR mediated by the AAV6 donor template. Quantification of T50 (time to reach half of the maximum editing frequency) indicates that short indels (especially +A/T) occur faster than longer (>2 bp) deletions, while the kinetics of HDR falls between NHEJ (non-homologous end-joining) and MMEJ (microhomology-mediated end-joining). As such, AAV6-mediated HDR effectively outcompetes the longer MMEJ-mediated deletions but not NHEJ-mediated indels. Notably, a combination of small molecular compounds M3814 and Trichostatin A (TSA), which potently inhibits predominant NHEJ repairs, leads to a 3-fold increase in HDR efficiency.
Parent-child aggression, adult-partner violence, and child outcomes: A prospective, population-based study

Parent-child physical aggression (PCPA) and adult intimate partner violence (IPV) are com- mon forms of family violence that often co-occur. Their deleterious effects on children and adolescents have been well documented. However, important questions remain regarding whether the type of violence exposure, the experience of one or both forms, the chronicity of violent experiences, and the age, gender, and SES of the child, differentially inﬂuence developmental outcomes. Data on 2810 children from the Project on Human Development in Chicago Neighborhoods were analyzed. Children aged 3–9 at the outset were assessed three times, at 3-year intervals. Primary caregivers reported on IPV, PCPA, and children’s externalizing and internalizing symptoms. Children’s externalizing and internalizing symp- toms were examined as a function of time, age, gender, socioeconomic status (SES), and the time-varying effects of cumulative IPV and PCPA exposure. Cumulative experiences of IPV and PCPA each adversely affected the developmental trajectories of both externalizing and internalizing symptoms, but in different ways; and they did so independently of participants’ age, gender, or SES, which all functioned as signiﬁcant, independent predic-tors of child outcomes. PCPA was by far the more potent of the two forms of violence; and when both forms occurred, they worked additively to affect outcomes. Important questions remain regarding the reasons for the differential potency of these two forms of family violence on childhood symptoms, and related implications for interventions, as well as for later adult behavior.
Clustering of lifestyle risk factors among adult population in India: A cross-sectional analysis from 2005 to 2016.

INTRODUCTION Individual's early life style and health behaviors are directly linked to chronic non-communicable diseases. Considering the increased burden of NCDs during the last two decades, the aim of this study is to assess co-occurrence/clustering of lifestyle risk factors and its association with different socio-demographic and economic characteristics among adult men and women in India from 2005-2016. METHODS This study utilized the data from the National Family Health Survey 2005-06 and 2015-16 survey rounds. Multinomial logistic regression is employed to evaluate co-occurrence of multiple risk factors among adult men and women of different socio-economic and demographic characteristics to identify the subgroups with elevated risk of clustering of multiple unhealthy lifestyle risk factors. RESULTS More adult men in India tend to exhibit clustering of multiple non-communicable disease risk factors than females. Individuals between 30-49 years of age, residing in urban areas, the population with no education, separated couples and those from poor economic strata are the specific population subgroups show higher prevalence of co-occurrence of multiple risk factors. The regional pattern of clustering of risk factors shows that the prevalence of co-occurrence of multiple risk factors is higher among men and women from the North-Eastern part of India compared to the other regions of the country. CONCLUSION The prevalence of clustering of multiple risk factors associated with chronic NCDs is substantially high and has increased between 2005-06 to 2015-16. India may therefore experience a significant increase in the burden of chronic non-communicable diseases in the coming years. We therefore conclude that appropriate strategies should be implemented by policy makers and the government to reduce the overall health burden of NCDs due to lifestyle habits.
Effect of pressure on Fe-Mg, Ni and Mn diffusion in (FeMg)SiO olivine

The pressure dependence of Fe-Mg interdiffusion coefficients, as well as of diffusion coefficients of the trace elements Ni and Mn in olivine, have been determined from diffusion anneals carried out using oriented single crystals in multianvil presses. This is the first determination of activation volumes of diffusion of trace elements (Ni, Mn) in olivine. Results from an isothermal polybaric (1673 K, 6 12 GPa) and an isobaric polythermal (1623 1823 K, 12 GPa) set of experiments were combined to constrain Manuscript
Oral potentially malignant disorders: new insights for future treatment.

PURPOSE OF REVIEW The purpose of this review is to define the issues regarding oral potentially malignant disorders (OPMDs) and provide an overview of currently available treatments and ongoing clinical trials for future opportunities. RECENT FINDINGS Nowadays, the treatment of choice of OPMD is surgery, whose role in preventing malignant transformation is however limited because of the high rate of recurrence and field cancerization. There have been several attempts of combining systemic therapies with surgery to reduce risk of malignant transformation. The identification of biomarkers that could predict malignant transformation is crucial in better tailoring the risk profile and possible therapeutic approaches. SUMMARY Loss of heterozygosity remains the most predictive marker of malignant transformation; however, role of specific microRNA and OPMD immune infiltration are emerging as potential biomarkers. Given the failure of previous trials with various chemopreventive strategies, new strategies should be defined to address the issue of systemic prevention of malignant transformation. Recent updates about immune infiltration and the immune-equilibrium concept for OPMD could shed light into new preventive approaches.
Ultrasound guidance may have advantages over landmark‐based guidance for some nerve conduction studies

Precise placement of stimulating and recording electrodes is vital when performing nerve conduction studies (NCSs). In this study, we aimed to determine whether ultrasonography (US) was more precise in localizing the superficial radial nerve (SRN), dorsal ulnar cutaneous nerve (DUCN), ulnar nerve (UN) crossing the cubital tunnel, and radial nerve (RN) crossing the spiral groove (SG) compared to conventional techniques.