Miracle-dz/UniFAR-FTUs huggingface dataset:
Agro-Entrepreneurial Intention among University Students: a study under the premises of Theory of Planned Behavior

This study empirically examines how graduate students’ attitude, subjective norm, perceived behavioral control, knowledge, and acceptance of agro-business influence student intention to start agro-entrepreneurship and the moderating effect of gender and faculty on the relationship among the factors based on the Theory of Planned Behavior. The study adopted the cross-sectional design from 300 public university students. The results of the study revealed that attitude toward agro-entrepreneurship, perceived behavioral control, and acceptance of agro-entrepreneurial exert a positive and significant effect on agro-entrepreneurial intention among university students. Moreover, the gender-based multiple group analysis revealed that male graduate students accept more agro-business than female students. Thus, policy makers can facilitate the promotion of agro-entrepreneurship among graduate students. Based on Theory of Planned Behavior, this study improves our understanding on university students’ agro-entrepreneurial intention in Malaysia. Finally, the discussion, recommendations and conclusion of the study are discussed in the research paper.
The feelings and coping strategies of children placed in Flemish family foster care

This article describes how 27 foster children aged 12 to 18 years old, placed in Flemish long-term family foster care, experience life in their foster family and how they cope with their feelings. Evidence from a combination of the children's selection of visual images displaying different emotions (emoticons) and semi-structured interviews shows that they mostly express positive feelings, such as happiness and pride, but simultaneously experience difficult emotions like sadness, anger and confusion. Positive feelings are mostly related to being able to feel like an ‘ordinary’ kid and negative ones to strained relationships with birth parents. Investigations into how the children cope with these emotions distinguished two groups: those who talk about their feelings with friends and other supportive figures and those who hide them. The latter group needs to be provided with strategies to better comprehend and express their feelings; among those suggested were activities that offer tranquility, consolation or distraction and having a private place for themselves. More attention to the emotional experiences of foster children and the ways they cope with their emotions is recommended in policy, practice and research if children's well-being is to be enhanced.
Corruption in Public Administration as a Brake on Transition to Industry 4.0

The transition to Industry 4.0 presumes the use of innovation potential which is also determined by the institutional environment, including the level of corruption and its perception. The post-communist countries of Central and Eastern Europe are characterized by a higher level of corruption and higher share of the shadow economy, which can fundamentally reduce their innovation potential and thus become the brake on the transition to Industry 4.0. The aim of this paper is thus to evaluate the effects of corruption in public administration on the size and structure of the shadow economy, and to determine whether the existence of corruption may affect the transition of a country and society to Industry 4.0. Based on an extended DSGE (Dynamic Stochastic General Equilibrium) model and using the data for the Czech Republic, the paper finds that corruption in public administration has a much more destructive and long-term effect on the capital accumulation than on the size of the workforce. In that sense, corruption can become a significant obstacle to the transition, underlining that the task of public policies is not only to support digitization, robotization, and further development of technologies, but especially to ensure a transparent non-corrupt environment of public administration.
Childlessness among adopted women: A study of the role of attachment through Bird’s Nest Drawings

Adopted adults are presented in the literature as having a more insecure attachment than the general population. They are also less likely to want to have children of their own, which is significant in that studies have shown that attachment is an important determinant of the desire for parenthood. The aim of the present study was to link these two findings and seek a better understanding of the role of attachment in adoptees’ choice of childlessness. Semi-structured interviews were conducted with seven nulliparous adopted women who did not wish to have children; during these interviews they also undertook the Bird’s Nest Drawing (BND) test. This allows access to participants’ parental representations in addition to measuring their attachment. Analysis of the drawings and associated stories suggested that insecure attachment (especially avoidant) is particularly decisive in the choice of childlessness. Their interview responses stressed adequate or inadequate mothering, self-sufficiency and threat to the family, which further indicated why the women chose not to have children. The theoretical and clinical implications of the findings are discussed, particularly the value of the Bird’s Nest Drawing test for adults who have experienced early discontinuities in their lives.
Two New Purine Alkaloids-based Magnetic Organic Substances and Their Characterization

In this study, magnetic theophylline and adenine were synthesized and characterized. The characteristic peaks of anion appeared in the ultraviolet spectra, infrared spectra, mass spectra and Raman spectrum, which indicated that the target magnetic molecules were successfully synthesized. At the same time, the contents of C, H and N in the magnetic theophylline were determined by elemental analysis and compared with the theoretical values in order to verify the structures identified by spectral data. The results also showed that the synthesized magnetic theophylline had high purity. Moreover, the magnetic properties of two kinds of magnetic molecules were measured by using vibrating sample magnetometer (VSM) analysis, and the coercivity and other important data could be determined from the hysteresis loops. It was concluded that the two molecules were paramagnetic. Finally, micro-reaction system was initially developed in this study for synthesizing such kind of magnetic molecules.
Solutions for nonhomogeneous fractional (p, q)-Laplacian systems with critical nonlinearities

Abstract In this article, we aimed to study a class of nonhomogeneous fractional (p, q)-Laplacian systems with critical nonlinearities as well as critical Hardy nonlinearities in R N {{\mathbb{R}}}^{N} . By appealing to a fixed point result and fractional Hardy-Sobolev inequality, the existence of nontrivial nonnegative solutions is obtained. In particular, we also consider Choquard-type nonlinearities in the second part of this article. More precisely, with the help of Hardy-Littlewood-Sobolev inequality, we obtain the existence of nontrivial solutions for the related systems based on the same approach. Finally, we obtain the corresponding existence results for the fractional (p, q)-Laplacian systems in the case of N = s p = l q N=sp=lq . It is worth pointing out that using fixed point argument to seek solutions for a class of nonhomogeneous fractional (p, q)-Laplacian systems is the main novelty of this article.
Perceptions Toward the Federal Flight Deck Officer Program and Willingness to Fly

In the aftermath of the September 11 terrorist attacks against the United States, numerous changes were implemented to aviation security. One of those programs was the arming of commercial airline pilots with handguns while they were on duty in a flight capacity. Since its inception, the Federal Flight Deck Officer (FFDO) program has been controversial in nature. The purpose of this study was to examine participant perceptions and their willingness to fly based on whether or not the pilot of their hypothetical flight was armed and participating in the FFDO program. A sample of 812 participants was selected from both India and the United States using Amazon’s Mechanical Turk® (MTurk). In general, the findings indicate that participants were more willing to fly when their pilot was armed; however, American females indicated no significant difference between the two conditions. Affect measures were also collected from participants and suggest that the relationship between the condition and the participants’ willingness to fly was mediated by emotions. The findings of the study provide information on participants’ view of the arming of pilots and suggest that, for the most part, participants in this study seem supportive of FFDO and the arming of pilots of commercial airliners. This finding is limited to participants who take part in online human intelligence tasks through services such as MTurk, who may or may not have been a commercial flight passenger.
The relationship of quality of life and selected sociodemographic factors in patients with inflammatory bowel disease

Abstract Introduction Inflammatory bowel disease (IBD) is a group of chronic inflammatory diseases of the gastrointestinal tract with relapsing-remitting episodes that are very burdensome for the patient. Understanding the sociodemographic factors that affect a patient’s quality of life helps us to better understand the behavior and life circumstances of the patient as well as the patient’s ability to cope with the stresses caused by IBD. Aim The aim of the study was to identify factors that affect the quality of life of patients with IBD. Material and methods The study involved 100 patients with confirmed IBD (50 subjects with Crohn’s disease and 50 subjects with ulcerative colitis). Women constituted 45% (n=45) of the study group, while the remaining 55% (n=55) of the group were men. The mean age of the respondents participating in the study was 37.27±13.38. The youngest patient was 20 years old and the oldest was 76. The respondents were treated at the Department of General and Colorectal Surgery and at the Department of Digestive Tract Diseases (both at Medical University in Łódź, Poland). Data were collected using the SF-36 general questionnaire, the IBDQ specific questionnaire, and the original author’s questionnaire. Participation in the study was anonymous and voluntary. A significance level of 0.05 was adopted in the statistical analysis. Results The study showed that the quality of life of IBD patients is reduced. The psychosocial factors influencing the quality of life of IBD patients include education, place of residence, professional activity, having a spouse, and lack of surgical intervention. However, no significant relationship was found between the respondents’ gender and age and their quality of life in any of the domains of the SF-36 and IBDQ questionnaire. Conclusions The occurrence of IBD, a chronic and incurable disease, reduces the quality of life of those patients. However, a higher level of education, living in a larger community, and increased physical activity all have a positive impact on the quality of life of patients with IBD.
Green synthesis of manganese-doped superparamagnetic iron oxide nanoparticles for the effective removal of Pb(ii) from aqueous solutions

Abstract In the current study, pure and manganese-doped superparamagnetic iron oxide nanoparticles (Mn-doped SPIONPs) were successfully prepared by a green approach using a fresh aqueous extract of Asparagus officinalis as a reducing and stabilizing agent. Magnetic behaviors of pure and Mn-doped SPIONPs were measured at room temperature against various field strengths by a vibrating sample magnetometer (VSM). The saturation magnetization was in the range of 5.39–2.07 emu. Absorption at 340 nm in the UV-visible spectrum confirmed the presence of iron oxide nanoparticles (IONPs). The presence of plant extract as a capping agent was confirmed by Fourier transform infrared (FTIR) spectroscopy. The crystalline nature of IONPs was confirmed by X-ray diffraction. A gradual increase in size was observed with increasing concentration of Mn. The synthesized materials were applied successfully as sorbent for the effective removal of lead ions (Pb(ii)). Experimental results of adsorption were also analyzed by Langmuir and Freundlich isotherm equations at different temperatures. The results suggested that sorption processes were spontaneous, and the synthesized SPIONPs displayed PbII removal capacity at higher loadings with q m of 21.3 and 29.56 mg·g−1 for undoped and 7% Mn-doped IOPNs, respectively, as compared to the commercial activated carbon.
Industrial evaluation of design heuristics for additive manufacturing

Abstract Additive manufacturing (AM) has gained prominence over the last 15 years and become a viable manufacturing option. Since there is great industrial interest to implement serial production of products using AM, the education of engineers in design for additive manufacturing (DfAM) is important today. DfAM extends on design for manufacturing to provide knowledge about the new design opportunities enabled by AM. A set of design heuristics for additive manufacturing (DHAM) to assist designers with conceptual-level DfAM has previously been proposed. In this paper, these DHAM are evaluated through workshops with 3 engineering companies and 19 engineers, in which the participants re-design existing company products for AM using the DHAM as an aid, and then give feedback. The DHAM are well received by the workshop participants, and they find that the DHAM are good for teaching others about the capabilities of AM, provide a checklist of items to consider to help avoid oversights, and encourage the generation of new ideas. Criticisms include the number of examples provided and the lack of information about how to implement the ideas concretely. It is also found that the DHAM fulfil 16 of 18 criteria for early design phase DfAM methods, identified in academic literature.
RAS mutation and associated risk of malignancy in the thyroid gland: An FNA study with cytology‐histology correlation

Activating point mutations of the RAS gene (NRAS, HRAS, and KRAS) can be seen in benign and malignant thyroid tumors; among these, NRAS mutations are more commonly seen. This study was conducted to evaluate the thyroid risk of malignancy (ROM) associated with RAS mutations in thyroid fine‐needle aspiration (FNA) at the authors' institution.
Nocardiosis diagnosed on bronchoalveolar lavage: Role of cytopathology

Nocardia are gram‐positive, filamentous bacteria that have the potential to cause serious disease, particularly in immunocompromised patients. Nocardia may cause a complex clinical picture, with radiologic features that can mimic other infectious organisms or malignancy. The organisms are not easily identified on cytologic examination given their weak staining with routine preparations and because they may be obscured by the associated inflammatory exudate. However, recognition of subtle features and a high index of suspicion in the appropriate clinical setting can lead to the appropriate triaging of material for ancillary stains and confirmatory microbiology tests. We herein present three cases of nocardiosis diagnosed on bronchoalveolar lavage in order to discuss the clinical presentation and cytomorphologic features with emphasis on the role of cytopathologists in facilitating timely diagnosis and helping direct appropriate management.
A partnership of the lipid scramblase XK and of the lipid transfer protein VPS13A at the plasma membrane

Chorea-acanthocytosis and McLeod syndrome are diseases with shared clinical manifestations caused by mutations in VPS13A and XK, respectively. Key features of these conditions are the degeneration of caudate neurons and the presence of abnormally shaped erythrocytes. XK belongs to a family of plasma membrane (PM) lipid scramblases whose action results in exposure of PtdSer at the cell surface. VPS13A is an ER-anchored lipid transfer protein with a putative role in the transport of lipids at contacts of the ER with other membranes. Recently VPS13A and XK were reported to interact by still unknown mechanisms. So far, however, there is no evidence for a colocalization of the two proteins at contacts of the ER with the PM, where XK resides, as VPS13A was shown to be localized at contacts between the ER and either mitochondria or lipid droplets. Here we show that VPS13A can also localize at ER-PM contacts via the binding of its PH domain to a cytosolic loop of XK, that such interaction is regulated by an intramolecular interaction within XK and that both VPS13A and XK are highly expressed in the caudate neurons. Binding of the PH domain of VPS13A to XK is competitive with its binding to intracellular membranes that mediate other tethering functions of VPS13A. Our findings support a model according to which VPS13A-dependent lipid transfer between the ER and the PM is coupled to lipid scrambling within the PM. They raise the possibility that defective cell surface exposure of PtdSer may be responsible for neurodegeneration.
Inhibiting presynaptic calcium channel mobility in the auditory cortex suppresses synchronized input processing

The emergent coherent population activity from thousands of stochastic neurons in the brain is believed to constitute a key neuronal mechanism for salient processing of external stimuli and its link to internal states like attention and perception. In the sensory cortex, functional cell assemblies are formed by recurrent excitation and inhibitory influences. The stochastic dynamics of each cell involved is largely orchestrated by presynaptic CAV2.1 voltage-gated calcium channels (VGCCs). Cav2.1 VGCCs initiate the release of neurotransmitters from the presynaptic compartment and are therefore able to add variability into synaptic transmission which can be partly explained by their mobile organization around docked vesicles. To investigate the relevance of Cav2.1 channel surface mobility for the input processing in the primary auditory cortex (A1) in vivo, we make use of a new optogenetic system which allows us to acutely cross-link Cav2.1 VGCCs via a photo-cross-linkable cryptochrome mutant, CRY2olig. In order to map neuronal activity across all cortical layers of the A1, we performed laminar current-source density (CSD) recordings with varying auditory stimulus sets in transgenic mice with a citrine tag on the N-terminus of the VGCCs. Clustering VGCCs suppresses overall sensory-evoked population activity, particularly when stimuli lead to a highly synchronized distribution of synaptic inputs. Our findings reveal the importance of membrane dynamics of presynaptic calcium channels for sensory encoding by dynamically adjusting network activity across a wide range of synaptic input strength. Statement of Significance Voltage Gated Calcium Channel (VGCC) mobility plays an important role in neuronal firing dynamics. Failure of these channels to function or be regulated has been linked to migraine and ataxia. We here link the microscopic process of VGCC mobility to the mesoscopic population dynamics as a mechanism to regulate and appropriately amplify synaptic inputs of different strengths to the mouse primary auditory cortex. We also demonstrate a novel and effective technique with which VGCC function can be further explored in meso- or macroscopic scales and with behaving subjects. We believe that this is of importance to the broader scientific community in aspects of non-linear scaling in the brain, potential translational applications, and basic research on cortical mechanisms of physiological function.
Proteomic characterization of spinal cord synaptoneurosomes from Tg-SOD1/G93A mice supports a role for MNK1 and local translation in the early stages of amyotrophic lateral sclerosis

The isolation of synaptoneurosomes (SNs) represents a useful means to study synaptic events. However, the size and density of synapses varies in different regions of the central nervous system (CNS), and this also depends on the experimental species studied, making it difficult to define a generic protocol for SNs preparation. To characterize synaptic failure in the spinal cord (SC) in the Tg-SOD1/G93A mouse model of amyotrophic lateral sclerosis (ALS), we applied a method we originally designed to isolate cortical and hippocampal SNs to SC tissue. Interestingly, we found that the SC SNs were isolated in a different gradient fraction to the cortical/hippocampal SNs. We compared the relative levels of synaptoneurosomal proteins in control (Tg-SOD1) animals, with Tg-SOD1/G93A mice at onset and those that were symptomatic using iTRAQ proteomics. The results obtained suggest that an important regulator of local synaptic translation, MNK1 (MAP kinase interacting serine/threonine kinase 1), might well influence the early stages of ALS.
Disruption of the microphysiological niche alters matrix deposition and causes loss of mitochondrial Ca2+ control in skeletal muscle fibers

Cells rapidly lose their physiological phenotype upon disruption of their extracellular matrix (ECM)-intracellular cytoskeleton interactions. Here, we investigated acute effects of ECM disruption on cellular and mitochondrial morphology, transcriptomic signatures, and Ca2+ handling in adult mouse skeletal muscle fibers. Adult skeletal muscle fibers were isolated from mouse toe muscle either by collagenase-induced dissociation of the ECM or by mechanical dissection that leaves the contiguous ECM intact. Experiments were generally performed four hours after cell isolation. At this time, there were striking differences in the gene expression patterns between fibers isolated with the two methods; 24h after cell isolation, enzymatically dissociated fibers had transcriptomic signatures resembling dystrophic phenotypes. Mitochondrial appearance was grossly similar in the two groups, but 3D electron microscopy revealed shorter and less branched mitochondria in enzymatically dissociated than in mechanically dissected fibers. Similar increases in free cytosolic [Ca2+] during repeated tetanic stimulation were accompanied by marked mitochondrial Ca2+ uptake only in enzymatically dissociated muscle fibers. The aberrant mitochondrial Ca2+ uptake was partially prevented by the mitochondrial Ca2+ uniporter inhibitor Ru360 and by cyclosporine A and NV556, which inhibit the mitochondrial protein Ppif (also called cyclophilin D). Importantly, inhibition of Ppif with NV556 significantly improved survival of mice with mitochondrial myopathy in which muscle mitochondria take up excessive amounts of Ca2+ even with an intact ECM. In conclusion, skeletal muscle fibers isolated by collagenase-induced dissociation of the ECM display aberrant mitochondrial Ca2+ uptake, which involves a Ppif-dependent mitochondrial Ca2+ influx resembling that observed in mitochondrial myopathies.