Miracle-dz/UniFAR-FTUs huggingface dataset:
Resolving some of the earliest names for Corallina species (Corallinales, Rhodophyta) in the North Pacific by sequencing type specimens and describing the cryptic C. hakodatensis sp. nov. and C. parva sp. nov.

Partial rbcL sequences from type specimens of three of the earliest described Corallina species showed that C. arbuscula (type locality: Unalaska Island, Alaska, USA) and C. pilulifera (type locality: Okhotsk Sea, Russia) are synonymous, with C. pilulifera as the taxonomically accepted name and that C. vancouveriensis (type locality: Botanical Beach, Vancouver Island, Canada) is a distinct species. To identify molecular species limits and clarify descriptions and distributions of C. pilulifera and C. vancouveriensis, we sequenced and analyzed portions of one mitochondrial and two plastid genes from historical and recent collections. The single‐gene phylogenetic reconstructions support the recognition of both species as distinct, as well as two additional species, C. hakodatensis sp. nov. and C. parva sp. nov., which are sister to, and often morphologically indistinguishable from C. pilulifera and C. vancouveriensis, respectively. DNA sequence data currently illustrate that C. pilulifera is found in the cold northern Pacific waters from the Okhotsk Sea of Russia to Hokkaido, Japan, eastward across the Aleutian Islands to Knoll Head, Alaska, and as far south as Nanaimo, British Columbia. Corallina vancouveriensis is distributed as far west as Attu Island in the Aleutian Islands to Sitka, Alaska, and southeasterly at numerous sites from British Columbia to the north of Point Conception, California, USA. The cryptic species C. hakodatensis and C. parva occur sympatrically with their sister species but with narrower ranges. The complex phylogenetic relationships shown by the single gene trees recommend Corallina as a model genus to explore coralline algal biogeography, evolution, and patterns of speciation.
Effect of Fatty Infiltration of the Infraspinatus Muscle on Outcomes and Graft Failure After Arthroscopic Superior Capsule Reconstruction for Irreparable Posterosuperior Rotator Cuff Tears

Background: Superior capsule reconstruction (SCR) was developed as an alternative treatment for irreparable rotator cuff tears to restore superior stability of the glenohumeral joint. Although fatty infiltration (FI) of the rotator cuff muscles, especially the infraspinatus, has been implicated as a predictor of outcomes and graft integrity after rotator cuff repair, it has not been fully investigated in cases of SCR. Purpose: To evaluate the effect of FI of the infraspinatus muscle on clinical and radiological outcomes after SCR. Study Design: Cohort study; Level of evidence, 3. Methods: A total of 55 consecutive patients with irreparable posterosuperior rotator cuff tears who underwent SCR between January 2013 and August 2020 were included retrospectively. Preoperative and postoperative clinical and radiological findings (median follow-up of >2 years), including magnetic resonance imaging results, were thoroughly reviewed. The patients were divided into 2 groups: group 1 with mild FI of the infraspinatus (Goutallier grades 0-2) and group 2 with severe FI of the infraspinatus (Goutallier grades 3-4). The American Shoulder and Elbow Surgeons score, Constant score, visual analog scale score for pain, and range of motion were evaluated. Acromiohumeral distance and rotator cuff tear arthropathy using the Hamada classification were assessed on plain radiography. Postoperative graft integrity was evaluated by magnetic resonance imaging. Graft failure was defined as complete discontinuity. Univariate and multivariable logistic regression analyses were performed to evaluate clinical and radiological findings that might be associated with successful SCR. Results: Clinical and radiological outcomes significantly improved after SCR. Graft failure was noted in 15 (27.3%) patients and was more frequent in group 2 than in group 1 (50.0% vs 14.3%, respectively; P = .004). Univariate analysis indicated a significant association between severe FI in the infraspinatus (group 2) and graft failure after SCR (odds ratio, 6.00 [95% CI, 1.65-21.80]; P = .006). Multivariable analysis indicated that FI of the infraspinatus was the only factor associated with graft failure (odds ratio, 6.37 [95% CI, 1.63-24.90]; P = .008). Conclusion: Severe FI of the infraspinatus muscle was a factor indicating a poor prognosis for graft integrity after SCR. Preoperative evaluation of FI in the rotator cuff muscles can help predict postoperative outcomes and may help guide therapeutic options.
Nucleon sigma term and strange quark content from lattice QCD with exact chiral symmetry

We calculate the nucleon sigma term in two-flavor lattice QCD utilizing the Feynman-Hellman theorem. Both sea and valence quarks are described by the overlap fermion formulation, which preserves exact chiral and flavor symmetries on the lattice. We analyze the lattice data for the nucleon mass using the analytical formulae derived from the baryon chiral perturbation theory. From the data at valence quark mass set different from sea quark mass, we may extract the sea quark contribution to the sigma term, which corresponds to the strange quark content. We find that the strange quark content is much smaller than the previous lattice calculations and phenomenological estimates.
Search for prompt production of χc and X(3872) in e+e- annihilations

We have searched for prompt production of χc1, χc2 and X(3872) in continuum e+e- annihilations using a 386fb-1 data sample collected around s=10.6GeV with the BABAR detector using the γJ/ψ decay mode. After accounting for the feed-down from ψ(2S)→γχc1,2, no significant signal for prompt χc1,2 production is observed. We present improved upper limits at 90% confidence level on the production cross sections of 77fb for χc1 and 79fb for χc2, for events where the χc momentum exceeds 2.0 GeV and there are at least three additional charged tracks. These limits are consistent with NRQCD predictions. We also set an upper limit on the prompt production of X(3872) through the decay X(3872)→γJ/ψ. © 2007 The American Physical Society.
On a new approach to the problem of the zero distribution of Hermite-Padé polynomials for a Nikishin system

A new approach to the problem of the zero distribution of Hermite-Pad\'e polynomials of type I for a pair of functions $f_1,f_2$ forming a Nikishin system is discussed. Unlike the traditional vector approach, we give an answer in terms of a scalar equilibrium problem with harmonic external field, which is posed on a two-sheeted Riemann surface.
Weak limits in non-linear conductivity

The problem of characterizing weak limits of sequences of solutions for a non-linear diffusion equation of $p$-laplacian type is addressed. It is formulated in terms of certain moments of underlying Young measures associated with main fields corresponding to the non-linear equation. We show two main results. One is a necessary condition; the other one a sufficient counterpart. Unlike the linear case, those two conditions do not match.
Performance of a Convolutional Neural Network Derived From PPG Signal in Classifying Sleep Stages

Automatic sleep stage classification is vital for evaluating the quality of sleep. Conventionally, sleep is monitored using multiple physiological sensors that are uncomfortable for long-term monitoring and require expert intervention. In this study, we propose an automatic technique for multi-stage sleep classification using photoplethysmographic (PPG) signal. We have proposed a convolutional neural network (CNN) that learns directly from the PPG signal and classifies multiple sleep stages. We developed models for two- (Wake-Sleep), three- (Wake-NREM-REM) and four- (Wake-Light sleep-Deep sleep-REM) stages of sleep classification. Our proposed approach shows an average classification accuracy of 94.4%, 94.2%, and 92.9% for two, three, and four stages, respectively. Experimental results show that the proposed CNN model outperforms existing state-of-the-art models (classical and deep learning) in the literature.
Phase 2 Trial of Baxdrostat for Treatment-Resistant Hypertension.

BACKGROUND Aldosterone synthase controls the synthesis of aldosterone and has been a pharmacologic target for the treatment of hypertension for several decades. Selective inhibition of aldosterone synthase is essential but difficult to achieve because cortisol synthesis is catalyzed by another enzyme that shares 93% sequence similarity with aldosterone synthase. In preclinical and phase 1 studies, baxdrostat had 100:1 selectivity for enzyme inhibition, and baxdrostat at several dose levels reduced plasma aldosterone levels but not cortisol levels. METHODS In this multicenter, placebo-controlled trial, we randomly assigned patients who had treatment-resistant hypertension, with blood pressure of 130/80 mm Hg or higher, and who were receiving stable doses of at least three antihypertensive agents, including a diuretic, to receive baxdrostat (0.5 mg, 1 mg, or 2 mg) once daily for 12 weeks or placebo. The primary end point was the change in systolic blood pressure from baseline to week 12 in each baxdrostat group as compared with the placebo group. RESULTS A total of 248 patients completed the trial. Dose-dependent changes in systolic blood pressure of -20.3 mm Hg, -17.5 mm Hg, -12.1 mm Hg, and -9.4 mm Hg were observed in the 2-mg, 1-mg, 0.5-mg, and placebo groups, respectively. The difference in the change in systolic blood pressure between the 2-mg group and the placebo group was -11.0 mm Hg (95% confidence interval [CI], -16.4 to -5.5; P<0.001), and the difference in this change between the 1-mg group and the placebo group was -8.1 mm Hg (95% CI, -13.5 to -2.8; P = 0.003). No deaths occurred during the trial, no serious adverse events were attributed by the investigators to baxdrostat, and there were no instances of adrenocortical insufficiency. Baxdrostat-related increases in the potassium level of 6.0 mmol per liter or greater occurred in 2 patients, but these increases did not recur after withdrawal and reinitiation of the drug. CONCLUSIONS Patients with treatment-resistant hypertension who received baxdrostat had dose-related reductions in blood pressure. (Funded by CinCor Pharma; BrigHTN ClinicalTrials.gov number, NCT04519658.).
Towards a mathematical formalism for classifying phases of matter

We propose a unified mathematical framework for classifying phases of matter. The framework is based on different types of combinatorial structures with a notion of locality called lattices. A tensor lattice is a local prescription that associates tensor networks to those lattices. Different lattices are related by local operations called moves. Those local operations define consistency conditions for the tensors of the tensor network, the solutions to which yield exactly solvable models for all kinds of phases. We implement the framework to obtain models for symmetry-breaking and topological phases in up to three space-time dimensions, their boundaries, defects, domain walls and symmetries, as well as their anyons for 2+1-dimensional systems. We also deliver ideas of how other kinds of phases, like SPT/SET, fermionic, free-fermionic, chiral, and critical phases, can be described within our framework. We also define another structure called contracted tensor lattices which generalize tensor lattices: The former associate tensors instead of tensor networks to lattices, and the consistency conditions for those tensors are defined by another kind of local operation called gluings. Using this generalization, our framework also covers mathematical structures like axiomatic (non-fully extended or defective) TQFTs, that do not directly describe phases on a microscopic physical level, but formalize certain aspects of potential phases, like the anyon statistics of 2+1-dimensional phases. We also introduce the very powerful concept of (contracted) tensor lattice mapping, unifying a lots of different operations, such as stacking, anyon fusion, anyon condensation, equivalence of different fixed point models, taking the Drinfel'd centre, trivial defects or interpreting a bosonic model as a fermionic model.
Sintilimab versus docetaxel as second‐line treatment in advanced or metastatic squamous non‐small‐cell lung cancer: an open‐label, randomized controlled phase 3 trial (ORIENT‐3)

Treatment options for Chinese patients with locally advanced or metastatic squamous‐cell non‐small‐cell lung cancer (sqNSCLC) after failure of first‐line chemotherapy are limited. This study (ORIENT‐3) aimed to evaluate the efficacy and safety of sintilimab versus docetaxel as second‐line treatment in patients with locally advanced or metastatic sqNSCLC.
Calabi-Yau modular forms in limit: Elliptic Fibrations

We study the limit of Calabi-Yau modular forms, and in particular, those resulting in classical modular forms. We then study two parameter families of elliptically fibred Calabi-Yau fourfolds and describe the modular forms arising from the degeneracy loci. In the case of elliptically fibred Calabi-Yau threefolds our approach gives a mathematical proof of many observations about modularity properties of topological string amplitudes starting with the work of Candelas, Font, Katz and Morrison. In the case of Calabi-Yau fourfolds we derive new identities not computed before.
The Witt group of non-degenerate braided fusion categories

Abstract We give a characterization of Drinfeld centers of fusion categories as non-degenerate braided fusion categories containing a Lagrangian algebra. Further we study the quotient of the monoid of non-degenerate braided fusion categories modulo the submonoid of the Drinfeld centers and show that its formal properties are similar to those of the classical Witt group.
Deconstruction of unparticles

We discuss properties of hypothetical scale invariant (unparticle) matter by viewing it as a tower of massive particles. We show how peculiar properties of unparticles emerge in the limit when the mass spacing parameter {delta} vanishes. We explain why the unparticle cannot decay in this limit and how, for finite {delta}, the decays manifest themselves in a relation between the reconstructed invariant mass and vertex displacement. We describe a model field theory in AdS{sub 5} which explicitly implements the deconstruction procedure by truncating the extra dimension to size of order 1/{delta}.
Quasiisometries of negatively curved homogeneous manifolds associated with Heisenberg groups

We study quasiisometries between negatively curved homogeneous manifolds associated with diagonalizable derivations on Heisenberg algebras. We classify these manifolds up to quasiisometry, and show that all quasiisometries between such manifolds (except when they are complex hyperbolic spaces) are almost similarities. We prove these results by studying the quasisymmetric maps on the ideal boundary of these manifolds.
Metabolic rate and climate change across latitudes: evidence of mass-dependent responses in aquatic amphipods

ABSTRACT Predictions of individual responses to climate change are often based on the assumption that temperature affects the metabolism of individuals independently of their body mass. However, empirical evidence indicates that interactive effects exist. Here, we investigated the response of individual standard metabolic rate (SMR) to annual temperature range and forecasted temperature rises of 0.6–1.2°C above the current maxima, under the conservative climate change scenario IPCC RCP2.6. As a model organism, we used the amphipod Gammarus insensibilis, collected across latitudes along the western coast of the Adriatic Sea down to the southernmost limit of the species' distributional range, with individuals varying in body mass (0.4–13.57 mg). Overall, we found that the effect of temperature on SMR is mass dependent. Within the annual temperature range, the mass-specific SMR of small/young individuals increased with temperature at a greater rate (activation energy: E=0.48 eV) than large/old individuals (E=0.29 eV), with a higher metabolic level for high-latitude than low-latitude populations. However, under the forecasted climate conditions, the mass-specific SMR of large individuals responded differently across latitudes. Unlike the higher-latitude population, whose mass-specific SMR increased in response to the forecasted climate change across all size classes, in the lower-latitude populations, this increase was not seen in large individuals. The larger/older conspecifics at lower latitudes could therefore be the first to experience the negative impacts of warming on metabolism-related processes. Although the ecological collapse of such a basic trophic level (aquatic amphipods) owing to climate change would have profound consequences for population ecology, the risk is significantly mitigated by phenotypic and genotypic adaptation.
Topological defects with power-law tails

We study interactions of kinks and antikinks of the (1 + 1)-dimensional ϕ8 model. In this model, there are kinks with mixed tail asymptotics: power-law behavior at one infinity versus exponential decay towards the other. We show that if a kink and an antikink face each other in way such that their power-law tails determine the kink-antikink interaction, then the force of their interaction decays slowly, as some negative power of distance between them. We estimate the force numerically using the collective coordinate approximation, and analytically via Manton’s method (making use of formulas derived for the kink and antikink tail asymptotics).
Soft X-ray excess in the Coma cluster from a Cosmic Axion Background

We show that the soft X-ray excess in the Coma cluster can be explained by a cosmic background of relativistic axion-like particles (ALPs) converting into photons in the cluster magnetic field. We provide a detailed self-contained review of the cluster soft X-ray excess, the proposed astrophysical explanations and the problems they face, and explain how a 0.1- 1 keV axion background naturally arises at reheating in many string theory models of the early universe. We study the morphology of the soft excess by numerically propagating axions through stochastic, multi-scale magnetic field models that are consistent with observations of Faraday rotation measures from Coma. By comparing to ROSAT observations of the 0.2- 0.4 keV soft excess, we find that the overall excess luminosity is easily reproduced for gaγγ ∼ 2 × 10-13 Ge -1. The resulting morphology is highly sensitive to the magnetic field power spectrum. For Gaussian magnetic field models, the observed soft excess morphology prefers magnetic field spectra with most power in coherence lengths on 𝒪(3 kpc) scales over those with most power on 𝒪(12 kpc) scales. Within this scenario, we bound the mean energy of the axion background to 50 eV≲ ⟨ Ea ⟩ ≲ 250 eV, the axion mass to ma ≲ 10-12 eV, and derive a lower bound on the axion-photon coupling gaγγ ≳ √(0.5/Δ Neff) 1.4 × 10-13 Ge -1.
Rational equivalence and Lagrangian tori on K3 surfaces

Fix a symplectic K3 surface X homologically mirror to an algebraic K3 surface Y by an equivalence taking a graded Lagrangian torus L in X to the skyscraper sheaf of a point y of Y. We show there are Lagrangian tori with vanishing Maslov class in X whose class in the Grothendieck group of the Fukaya category is not generated by Lagrangian spheres. This is mirror to a statement about the `Beauville--Voisin subring' in the Chow groups of Y, and fits into a conjectural relationship between Lagrangian cobordism and rational equivalence of algebraic cycles.
Partial replacement of red and processed meat with legumes: a modelling study of the impact on nutrient intakes and nutrient adequacy on the population level

Abstract Objective: The shift towards plant-based diets with less meat and more legumes is a global target and requires an understanding of the consequences of dietary adequacy on the population level. Our aim was to model the impact of partial replacement of red and processed meat with legumes on nutrient intakes and population shares below dietary reference intakes. Design: Modelling study with three scenarios anchored in meat cut-offs: ≤ 70 g/d (Finnish dietary guideline); ≤ 50 g/d (Danish dietary guideline); ≤ 30 g/d (EAT-Lancet recommendation). In all subjects, the amount of meat in grams over the cut-off was replaced with the same amount of legumes. The SPADE method was used to model usual intake distributions. Meaningful differences in average intakes and in population shares below dietary reference intakes compared to the reference (FinDiet) were evaluated based on non-overlapping 95 % CI. Setting: Finnish national food consumption survey (FinDiet 2017). Subjects: Finnish adults (n 1655) aged18–74 years (47 % men). Results: The scenarios introduced increases in the average intakes of fibre, folate, K, Mg, Cu and Fe, and decreases in intakes of saturated fat, niacin, vitamin B12, Se and Zn. Meaningful shifts of the usual intake distributions of fibre and folate towards improvement in intakes emerged already in ‘scenario 70 g’. Overall, distribution shifts towards a higher probability of inadequate intakes of the studied nutrients were not observed. Conclusions: These results support the public health message to partly replace meat with legumes and may benefit nutrition policy actions towards sustainable diets in the Nordic countries and beyond.
Classification of a family of non-almost-periodic free Araki–Woods factors

We obtain a complete classification of a large class of non almost periodic free Araki-Woods factors $\Gamma(\mu,m)"$ up to isomorphism. We do this by showing that free Araki-Woods factors $\Gamma(\mu, m)"$ arising from finite symmetric Borel measures $\mu$ on $\mathbf{R}$ whose atomic part $\mu_a$ is nonzero and not concentrated on $\{0\}$ have the joint measure class $\mathcal C(\bigvee_{k \geq 1} \mu^{\ast k})$ as an invariant. Our key technical result is a deformation/rigidity criterion for the unitary conjugacy of two faithful normal states. We use this to also deduce rigidity and classification theorems for free product von Neumann algebras.
Inverse limits as attractors in parameterized families

We show how a parameterized family of maps of the spine of a manifold can be used to construct a family of homeomorphisms of the ambient manifold which have the inverse limits of the spine maps as global attractors. We describe applications to unimodal families of interval maps, to rotation sets, and to the standard family of circle maps.
Finiteness of cohomology groups of stacks of shtukas as modules over
 Hecke algebras, and applications

In this paper we prove that the cohomology groups with compact support of stacks of shtukas are modules of finite type over a Hecke algebra. As an application, we extend the construction of excursion operators, defined by V. Lafforgue on the space of cuspidal automorphic forms, to the space of automorphic forms with compact support. This gives the Langlands parametrization for some quotient spaces of the latter, which is compatible with the constant term morphism. Comment: published version