Miracle-dz/UniFAR-FTUs huggingface dataset:
Machine learning-based neddylation landscape indicates different prognosis and immune microenvironment in endometrial cancer

Endometrial cancer (EC) is women’s fourth most common malignant tumor. Neddylation plays a significant role in many diseases; however, the effect of neddylation and neddylation-related genes (NRGs) on EC is rarely reported. In this study, we first used MLN4924 to affect the activation of neddylation in different cell lines (Ishikawa and HEC-1-A) and determined the critical role of neddylation-related pathways for EC progression. Subsequently, we screened 17 prognostic NRGs based on expression files of the TCGA-UCEC cohort. Based on unsupervised consensus clustering analysis, patients with EC were classified into two neddylation patterns (C1 and C2). In terms of prognosis, substantial differences were observed between the two patterns. Compared with C2, C1 exhibited low levels of immune infiltration and promoted tumor progression. More importantly, based on the expression of 17 prognostic NRGs, we transformed nine machine-learning algorithms into 89 combinations. The random forest (RSF) was selected to construct the neddylation-related risk score according to the average C-index of different cohorts. Notably, our score had important clinical implications for EC. Patients with high scores have poor prognoses and a cold tumor state. In conclusion, neddylation-related patterns and scores can distinguish tumor microenvironment (TME) and prognosis and guide personalized treatment in patients with EC.
Does Intradialytic Group Exercise Programme Influence Patient-Reported Outcomes, Laboratory Parameters, and Anthropometric Parameters in Maintenance Hemodialysis Patients? A Single-Group Repeated-Measures Trial

Background Maintenance hemodialysis(MHD) patients often suffer from fatigue and are recommended to undertake physical activities. The optimal format of exercise rehabilitation for MHD patients remains uncertain despite demonstrated health benefits. This study aimed to evaluate the effectiveness of an intradialytic group exercise programme for MHD patients. Methods This was a single-centre, single-group repeated-measures design study. The 12-week, three times per-week intradialytic group exercise programme was conducted for around 30 min during the first 2 hours of each dialysis session. Patient-reported outcomes including fatigue, anxiety, depression and health-related quality of life, laboratory parameters including haemoglobin, albumin, pre-albumin and hypersensitive C-reactive protein, and anthropometric parameters including triceps skinfold thickness, mid-upper arm circumference, mid-arm muscle circumference and handgrip strength, were measured at baseline, immediately post-intervention and 12-weeks post-intervention. The repeated-measures analysis of variance and Friedman test were used to compare the parametric and non‐parametric data across time points, respectively. Results Ninety patients were enrolled and 75 completed. Participants reported significant improvements across time points in fatigue (F = 10.19, p < 0.01), depression (F = 19.20, p < 0.001), health-related quality of life (F = 5.36, p = 0.006), haemoglobin (F = 3.43, p = 0.047), albumin (F = 4.42, p = 0.032), hypersensitive C-reactive protein (χ2 = 50.39, p < 0.001), pre-albumin (χ2 = 11.85, p = 0.003), triceps skinfold thickness (F = 25.03, p < 0.001), mid-upper arm circumference (F = 6.32, p = 0.005), mid-arm muscle circumference (F = 4.89, p = 0.02), and handgrip strength (F = 13.59, p < 0.001). Although the mean anxiety score tended to reduce, the difference across time points was nonsignificant (F = 1.33, p = 0.27). Conclusion The findings suggested that the intradialytic group exercise programme could improve MHD patients’ fatigue, depression, health-related quality of life, nutritional status, and inflammation. Trial Registration Chinese Clinical Trial Registry ChiCTR2000034394 (04/07/2020).
The head-on interaction of two solitary waves of unequal amplitude

In this paper we consider the interaction of two unequal solitary waves travelling in opposite directions. The interaction equations are derived from the perturbation expansion of the Euler equations, which lead to the Boussinesq equation at lowest order. These equations are recast to obtain two weakly coupled KdV equations which are solved by the method of inverse scattering. We show that the amplitude of each solitary wave after interaction is reduced. This change in the amplitudes is shown to be fifth order in ε, the order of magnitude of the amplitude of the waves. This is in agreement with the change of amplitude produced by the interaction of two equal waves which arises in the reflection of a wave by a vertical wall.
The Rater Bundle Model

In this article an item response model is introduced for repeated ratings of student work, which we have called the Rater Bundle Model (RBM). Development of this model was motivated by the observation that when repeated ratings occur, the assumption of conditional independence is violated, and hence current state-of-the-art item response models, such as the rater facets model, that ignore this violation, underestimate measurement error, and overestimate reliability. In the rater bundle model these dependencies are explicitly parameterized. The model is applied to both real and simulated data to illustrate the approach.
Influence of temperature-humidity index, calf sex, and parity on gestation length in Holstein cows

Abstract: The present study aimed to analyse the gestation length (GL) variability in locally born purebred Holstein dams (n = 1047), in a private farm, under Saharan climate. The overall GL mean was 278.73 ± 6.67 days. A general linear model revealed that the GL was significantly affected by calf sex (p = 0.035) with a minor increase of 0.19% in males, dam parity (p = 0.016) and calving season (p < 0.0001) including the shortest lengths recorded in heifers and during heat stress period. Moreover, a negative regression (–1.96%) in recent years was recorded in GL by the influence (p = 0.01) of years of birth, breeding, and calving of cows. Our findings show that cows that were inseminated and gave birth during the cold season (temperature-humidity index, THI < 74) had 11.54 days longer (p = 0.048) gestation period compared to animals that were inseminated and gave birth during the hot season (THI > 84). Similarly, the association (p = 0.003) between dam parity and calf sex revealed that the GL of multiparous cows that gave birth to male calves was higher (3.07 days) than that of male calves from heifers. The findings can contribute to a better understanding of the environmental and animal factors association’s effects on GL in Holstein cows under hyperarid zone and assisting in the adequate management of pregnant females.
Accounting for non-photosynthetic vegetation in remote-sensing-based estimates of carbon flux in wetlands

Monitoring productivity in coastal wetlands is important due to their high carbon sequestration rates and potential role in climate change mitigation. We tested agricultural- and forest-based methods for estimating the fraction of absorbed photosynthetically active radiation (f APAR), a key parameter for modelling gross primary productivity (GPP), in a restored, managed wetland with a dense litter layer of non-photosynthetic vegetation, and we compared the difference in canopy light transmission between a tidally influenced wetland and the managed wetland. The presence of litter reduced correlations between spectral vegetation indices and f APAR. In the managed wetland, a two-band vegetation index incorporating simulated World View-2 or Hyperion green and near-infrared bands, collected with a field spectroradiometer, significantly correlated with f APAR only when measured above the litter layer, not at the ground where measurements typically occur. Measures of GPP in these systems are difficult to capture via remote sensing, and require an investment of sampling effort, practical methods for measuring green leaf area and accounting for background effects of litter and water.
Teachers’ views on ‘food’ animals for sustainability education: an exploratory study

Abstract Sustainability education is crucial in helping students deal with current health and environmental challenges through dietary choices. This study aims to provide an understanding of how the teachers surveyed (n = 416, 85% women; 58% teaching natural sciences) view the importance of the following interrelated issues for sustainability: (1) the viability of diets for tackling environmental challenges and natural resource management; (2) the health benefits of traditional versus plant-based diets; and (3) the impacts of factory farming on animals and animal sentience. Most participants recognised the importance of a sustainable education model that encourages reducing meat consumption while adopting healthy plant-based diets. Furthermore, the majority recognise animal sentience and agree that schools should address the negative impacts of factory farming on animals and the environment. The results are striking, as they indicate that most teachers’ views contrast with the traditionalist and instrumental portrayal of animals in national core curricula.
Universal size and shape of viscous capillary jets: application to gas-focused microjets

The size and shape of capillary microjets are analysed theoretically and experimentally. We focus on the particular case of gas-focused viscous microjets, which are shaped by both the pressure drop in the axial direction occurring in front of the discharge orifice, and the tangential viscous stress caused by the difference between the velocities of the co-flowing gas stream and liquid jet behind the orifice. The momentum equation obtained from the slender approximation reveals that the momentum injected into the jet in these two regions is proportional to the ratio of the pressure drop to the orifice diameter. Thus, the liquid-driving forces can be reduced to a single term in the momentum equation. Besides, the size and shape of gas-focused microjets were experimentally measured. The experiments indicated that the Weber number has a minor influence on the jet diameter for steady, stable jets, while both the axial coordinate and the Reynolds number affect its size significantly. When the experimental results are expressed in terms of conveniently scaled variables, one obtains a remarkable collapse of all measured jet diameters into a single curve. The curve matches a universal self-similar solution of the momentum equation for a constant driving force, first calculated by Clarke (Mathematika, vol. 12, 1966, p. 51) and not yet exploited in the field of steady tip-streaming flows, such as flow focusing and electrospray. This result shows that the driving force or motor mentioned above attains a rather homogeneous value at the region where the gas-focused microjet develops. The approach used in this work can also be applied to study other varied microjet generation means (e.g. co-flowing, electrospray and electrospinning).
Shifts on compact and discrete Lie groups:algebraic-topological invariants and classification problems

Abstract This paper is devoted to an investigation of various dynamical concepts for group shift systems which are invariant by algebraic conjugacy (i.e., topological conjugacy preserving the group structure). The concept of controllability, which is stronger than topological transitivity, and the concept of limit dimension, which is analogous to topological entropy, are discussed at length. Particular attention is dedicated to the abelian case, for which duality results are also established.
Excitation of an infinite antenna above a dissipative earth

The antenna problem consisting of exciting an infinitely long horizontal thin wire with an arbitrary distribution of impressed electric field along the axis of the wire is discussed. The special case of excitation by a delta function voltage source is solved. The current on the antenna is found as a sum of two residue (discrete) contributions and two branch integration (continuous) contributions. The far field and orthogonality properties of both the discrete and continuous modes are discussed. Finally, expressions are given for the current on the antenna. From this current the input conductance of the antenna can be obtained.
Modeling electron and hole transport with full-band structure effects by means of the Spherical-Harmonics Expansion of the BTE

The Spherical-Harmonics solution of the Boltzmann Transport Equation (BTE) in silicon is generalized to the full-band case for both electrons and holes. The relevant scattering mechanisms, including impact ionization, are modeled consistently. Comparison with experimental data and Monte Carlo (MC) analysis emphasize the importance of a correct description of the band structure and impact ionization especially in the analysis of carrier transport at high energies, and the ability of the Spherical-Harmonics Expansion (SHE) scheme to efficiently incorporate the features of the transport mechanisms to a rather general extent.
Simulation of the Asian summer monsoon and its dependence on model horizontal resolution

The 1986-1989 Asian summer monsoons have been simulated using a state-of-the-art atmospheric General Circulation Model (GCM), spectrally truncated at 63, 42, 31 and 21 total wavenumbers, corresponding to horizontal resolutions ranging from 200-600 km. The mean June-September Asian monsoons have been analyzed and compared to the observed mean monsoon behaviour. Large-scale features such as the lower tropospheric westerly jet, the upper tropospheric tropical easterlies, the Tibetan anticyclone, and copious rainfall over continental Asia are captured by the model at all resolutions. As the resolution is increased, the core of the low-level westerly jet moves towards Somalia and becomes more realistic. The model, however, produces excessive precipitation over the equatorial Indian Ocean and over the southern slopes of the Tibetan plateau, and these errors become accentuated at higher resolution. Furthermore, the monsoon is displaced southward at higher resolutions as is clearly evidenced by a shift in the position of the Tibetan anticyclone. A budget analysis of the upper-level vorticity suggests that this may be related to the excessive ascent over the southern slopes of the Tibetan plateau. A smooth orography test has been made at T63 truncation using T21 truncated orography, in order to assess the contribution due to orographic changes. Smooth orography alleviates the excessive precipitation over the southern slopes of the Tibetan plateau and has a strong and generally beneficial impact on the monsoon over land. It also gives large-scale dynamical monsoon indices in better agreement with observations, yet does not alleviate the excessive precipitation over the equatorial Indian Ocean. The excessive oceanic precipitation is partly due to a systematic intensification of the equatorial convergence zones with increased resolution, yet this appears to be only weakly coupled to the dynamics of the monsoon circulation.
Motion of individual domain walls in a nickel-iron ferrite

Samples have been cut from single crystals of the nickel-iron ferrite (NiO) 0.75 (FeO 0.25 Fe 2 O 3 in such a way that they contain one and only one movable ferromagnetic domain wall. The viscous damping coefficient for this wall, which is a measure of the losses associated with domain wall motion in this material, has been measured as a function of temperature. This damping shows a very large increase as the temperature goes down to the region of 77°K. The value of this damping is correlated with the Landau-Lifshitz equation for the rotational motion of magnetization by means of previously available theoretical analysis. In addition, it is suggested that the sharp increase in damping at low temperatures is due to a relaxation associated with a rearrangement of the valence electrons on the divalent and trivalent iron ions in the ferrite. A tentative phenomenological theory of the losses based on this mechanism is presented.
Automatic continuity of certain isomorphisms between regular Banach function algebras

Abstract Let A and B be regular semisimple commutative Banach algebras; that is to say, regular Banach function algebras. A linear map T denned from A into B is said to be separating or disjointness preserving if f.g = 0 implies Tf.Tg = 0, for all f, g ∈ A In this paper we prove that if A satisfies Ditkin's condition then a separating bijection is automatically continuous and its inverse is separating. If also B satisfies Ditkin's condition, then it induces a homeomorphism between the structure spaces of A and B.
The Primordial Helium Abundance: Systematic Effects and a New Determination

We present new high-quality spectrophotometric observations of 27 supergiant H II regions in 23 low-metallicity blue compact galaxies (BCGs) with oxygen abundance 12 + log (O/H) between 7.22 and 8.17 (Z☉/50 ≤ Z ≤ Z☉/6), most of which were selected from the first and second Byurakan objective-prism surveys. Combining this new data with our previous sample of 10 low-metallicity BCGs, we extract a subsample of 27 H II regions in 24 BCGs most appropriate for the determination of the primordial helium abundance Yp. We find that the most metal-deficient BCG known, I Zw 18 (Z ~ Z☉/50), cannot be used for this purpose because of its abnormally low He I line intensities. We have examined critically the systematic effects that may influence the determination of Yp. We find that the effects of the corrections for neutral helium and for underlying stellar absorption in the He I lines, possible deviations from case B recombination theory, fluorescent enhancement of the He I line intensities, temperature fluctuations in H II regions, Wolf-Rayet stellar winds, and supernova shock waves to be small. The main effect comes from the particular set of atomic data used. The best set of atomic data for use in the determination of Yp is composed of Smits's He I emissivities and Kingdon & Ferland's collisional enhancement correction factors. This set gives the smallest dispersion of the data in the Y-O/H and Y-N/H planes and corrects best the data for collisional enhancement effects. By extrapolating the Y versus O/H and Y versus N/H linear regressions to O/H = N/H = 0, we obtain Yp = 0.243 ± 0.003 for both regressions, considerably larger than the values derived before. In the framework of the standard hot big bang nucleosynthesis model with a number of neutrino families Nν = 3 and a neutron half-lifetime τn = 887 s, our new Yp gives a baryon-to-photon number ratio η=3.51. 0−0.7 × 10-10, or a baryonic mass fraction Ωh250=0.05±0.01. Our Yp determination is fully consistent with measurements of the primordial 7Li in Galactic halo stars and of (D +3He) in the local interstellar medium and the solar system, and consistent at the 2 σ level with the primordial D abundance derived in a quasar absorption system by Tytler, Fan, & Burles. We derive a slope dY/dZ = 1.7 ± 0.9, considerably smaller than the slopes obtained before and consistent with chemical evolution models for star-forming dwarf galaxies with an outflow of well-mixed material. Extrapolation to solar metallicity with such a slope gives the correct solar helium mass fraction within the errors.
COVID-19 and the Mental Health Crisis Faced by Students From a Private University in the Philippines: A Phenomenological Study

The focus of this study was the students lived experiences and perspectives of the COVID-19 pandemic and its associated lockdowns. Although there is considerable quantitative evidence that the pandemic significantly strained the general population's mental health, qualitative attempts to explore the psychosocial determinants that could have moderated and mitigated its adverse effects are limited. Based on empirical phenomenological methods of inquiry, this study aimed to provide a more eidetic portrait of the lived experience of the pandemic-induced environment from the perspective of 36 first-year college students from a private university in the Philippines. A thematic analysis of their responses to the online structured written interview surfaced three strands that enabled them to cope, adapt, and even thrive: finding the family, finding faith, and finding meaning. The researchers recommend that youth ministers, positive psychology practitioners, and school guidance counselors enact and implement programs that can strengthen the supportive role of family and religion to enable the youth to respond well to the current pandemic and beyond.
Boundary element method applied to the bending analysis of thin functionally graded plates

The present work introduces the boundary element method applied to the bending analysis of functionally graded plates. It is assumed that material properties are graded through the thickness direction of the plate according to a power law distribution. The neutral surface position for such plate is determined and the classical plate theory based on the exact neutral surface position is employed to extract the equilibrium equations. A direct approach based on the Green's identity is used to formulate boundary element method. By introducing a novel approach, domain integrals which arise from distributed transverse loads are transformed into boundary integrals. In case studies, three geometrical shapes including, rectangular, circular and elliptic for functionally graded plates with/without hole are considered. Comparative studies are first carried out to evaluate the sufficiency of the proposed method for bending analysis of isotropic and functionally graded plates subjected to the transverse loads. Then, a series parametric study is performed to examine the influences of the power of functionally graded material, boundary conditions and geometrical parameters on the deformation and stress of functionally graded plates.
Deformation Quantization for Actions of R ]D

Oscillatory integrals The deformed product Function algebras The algebra of bounded operators Functoriality for the operator norm Norms of deformed deformations Smooth vectors, and exactness Continuous fields Strict deformation quantization Old examples The quantum Euclidean closed disk and quantum quadrant The algebraists quantum plane, and quantum groups References.
Spatial modelling of snow water equivalent using airborne and ground- based snow data

As the population and industrial infrastructure of the United States continue to grow, the demand for water and the need to forecast water resources accurately are intensifying. Hence, the National Weather Service maintains a set of conceptual, continuous, hydrologic simulation models used to generate extended streamflow predictions, water supply outlooks and flood forecasts that are the basis for major water management and disaster emergency services decisions for the United States. A vital component of the hydrologic simulation models is a snow accumulation and ablation model that uses observed temperature and precipitation data to simulate snow cover conditions. The simulated model states are updated throughout the snow season using snow water equivalent estimates obtained from airborne and ground-based snow water equivalent data. The National Weather Service has developed a spatial model to obtain integrated snow water equivalent estimates for updating the snow model; however, it is designed to incorporate only ground-based data. In this research, we describe the spatial model and show how to modify it to include data of two different supports (the airborne and ground-based data) so that more precise integrated snow water equivalent estimates can be obtained. The results are illustrated on snow data collected in the Upper Colorado River basin.