Miracle-dz/UniFAR-FTUs huggingface dataset:
Thromboprophylaxis after orthopaedic surgery with an oral, direct factor Xa inhibitor: Pooled results of two phase Iib clinical trials.

Thromboembolic events, such as deep vein thrombosis (DVT) and pulmonary embolism (PE), are a serious risk after surgical procedures, such as major orthopaedic surgery. BAY 59-7939 is an oral, direct Factor Xa inhibitor in clinical development for the prevention and treatment of thromboembolic disorders. The efficacy and safety of BAY 59-7939 for thromboprophylaxis have been determined relative to enoxaparin in two clinical trials, one after elective total hip replacement surgery, and one after elective total knee replacement surgery. Both trials were multicenter, multinational, double-blind, dose-ranging studies; the hip surgery trial was performed in Europe, and the knee surgery trial in North America. This pre-specified analysis combines data from both trials. Patients (n=1343) were randomized to oral BAY 59-7939 at 2.5, 5, 10, 20, or 30 mg twice daily (bid), or subcutaneous enoxaparin (40 mg once daily starting 12 hours before hip surgery, or 30 mg bid starting 12 hours after knee surgery). Treatment continued until mandatory bilateral venography was performed 5–9 days after surgery. The primary efficacy endpoint was a composite of DVT, PE, and all-cause mortality, and was analyzed in 914 per-protocol patients. The secondary efficacy endpoint was major venous thromboembolism (VTE) - proximal DVT, PE, and VTE-related death. The primary safety endpoint was major, post-operative bleeding, and was analyzed in 1317 patients. Observed pooled event rates are shown in the table. No significant dose-response relationship for efficacy was observed with BAY 59-7939 ( P =0.39 and P =0.46 for primary and secondary endpoints, respectively) in logistic regression models using total daily dose and adjusting for study, age and gender effects; this was potentially due to the efficacy achieved with the lower BAY 59-7939 doses. A significant dose-response relationship was observed for major, post-operative bleeding with BAY 59-7939 ( P
The relation between the cancer characteristics and quality of life in the patients under chemotherapy

هدیکچ هدـنیآ یاهتفرشیپ و رثؤم یاهنامرد یاشگ هار اهنت هن یگدنز تیفیک دروم رد تاعلاطا هب یبایتسد :همدقم . دشابیم رثؤم رایسب یشخبناوت تامادقا و یتیامح یاههمانرب ءاقترا رد هکلب تسا طاـ بترا یـسررب روظنم هب هک تسا یطابترا عون زا یعطقم یفیصوت هعلاطم کی رضاح شهوژپ :راک شور و داوم یژوـلوکنا بـختنم هاــ گنامرد هب هدننکهعجارم ینامرد یمیش تحت یناطرس نارامیب رد یگدنز تیفیک و ناطرس یاهیگژیو (رپوت یاهروموت) ناطرس عاونا هب لاتبم نارامیب زا رفن 200 قیقحت نیا رد . تسا هتفرگ تروص نارهت یکشزپ مولع هاگشناد یاهمانـ شسرپ تاـ علاطا یروآدرـگ رازبا . دندش باختنا فده رب ینتبم یریگهنومن تروص هب دندوب ینامرد یمیش تحت هک ،لوا شخب :دوب شخب هس لماش و تشگیم لیمکت رامیب هدنورپ هب هعجارم و رامیب دوخ شرازگ ،هبحاصم قیرط زا هک دوب ،یراـمیب تدـم لوط ،ناطرس هلحرم ،ناطرس عون لیبق زا ناطرس یاهیگژیو ،مود شخب ؛کیفارگومد تایصوصخ نازیـم و ندـب ءاـضعا درـکلمع نداد تــسد زا ای شهاک ،رامیب طسوت ناطرس راکنا ای لوبق ،ناطرس زا یشان درد ،یلغـش تـیعضو ،یمـسج تیلاعف ،یمومع تیعضو ریظن یگدنز تیفیک داعبا یسررب لماش ،موس شخب و یگتسخ . باوخ و یعامتجا طـسوتم (%66) شـهوژپ دروــم یاهدحاو تیرثکا یگدنز تیفیک هک دوب نآرگنایب شهوژپ یاههتفای :اههتفای ناطرـس عوـن نـیب هـک داد ناـشن جیاـتن یـگدـنز تـیفیک اـب ناطرـس یاــ هیگژیو طابترا صوصخ رد . تسا هدوب یگتـسخ تدـش و (p=0/001) ندـب ءاـضعا درـکلمع نداد تـسد زا اــی شهاک ،(p=0/007) درد تدش ،(p=0/007) زا یراـمیب تدـم لوـط ،یراــ میب راکنا ای لوبق نیب یلو تشاد دوجو یرادانعم طابترا یگدنز تیفیک اب (p=0/000) . تشادن دوجو یرادانعم طابترا یگدنز تیفیک اب ناطرس هلحرم و صیخشت نامز ءاضعا درکلمع نداد تسد زا ای شهاک ،درد ،ناطرس عون هلمج زا ناطرس یاهیگژیو زا یخرب :یریگهجیتن . دراد ریثأت ینامردیمیش تحت نارامیب یگدنز تیفیک رب یگتسخ و
Record Keeping Practices of Secondary School Principals: An Enugu State Education Zone Study

This study was designed to establish record keeping practices of secondary school principals in Enugu State Education Zone and problems associated with keeping of records. The study was a descriptive research design guided by four research questions. Questionnaire, titled “Record Keeping Practice of Secondary school Principals in Enugu Education Zone of Enugu State” which was designed by the researcher was used for data collection. 650 secondary school teachers and 28 principals from Enugu Education Zone of Enugu State were used for the study; thereby bringing the total study population to 678. Data was analyzed using mean and the level of acceptance for answering each research question was based on a mean of 2.5 and above on four point rating scale. The result among others shows that secondary school principals and teachers in Enugu State indicated that records presently kept in their schools include admission register, attendance register, weekly diaries of work, log book, visitor’s book, staff record register, staff minutes book, school time-table, punishment book, school accounts books and education edict and regulation Manual. It was the opinions of the secondary school principals and teachers that the administrative practices that characterize the keeping of day to day administrative records to senior teachers, record events as they occur in the appropriate record booklets, keep accurate custody of record materials and books in the offices, check every item of information in the records before appending their signatures and monitor teachers’ adherence to instructions on the keeping of records. There was no significant difference between the opinions of secondary school teachers and principals with regard to the administrative practices that characterize the keeping of records in secondary schools in Enugu Education Zone. Based on findings of the study, recommendations were made.
Contrast-enhanced ultrasound in the assessment of the transitional zone of microwave ablations in an ex vivo perfused liver model; is it a useful tool?

Background and Aims: Microwave ablation (MWA) under different imaging guidance is a new technique for treating liver malignancies. The ablation creates a transitional zone at the periphery of the ablated region. In this zone, few cancer cells might escape heat causing local recurrence. Therefore, a more defined transitional zone is required to avoid residual cancer. Study Design: Experimental study with a block design. Place and Duration of Study: Departments of Hepatobiliary and Pancreatic surgery, department of Radiology and department of Histopathology; University hospitals of Leicester, UK. May-July Original Research Article Alzaraa et al.; BJMMR, 8(4): 298-312, 2015; Article no.BJMMR. 2015.452 299 2011. Methodology: MWA with different powers (50 W, 70 W, 90 W) were created in five ex vivo perfused porcine livers. The ablations were evaluated on morphology, grey-scale US, CEUS and histology. Statistical analysis of the data was performed using ANOVA test. Results: CEUS showed better demarcation of the lesion’s border when compared with the greyscale US. There was a significant difference in the long axis of the ablation among morphology, grey-scale US and CEUS (P < 0.0001), and a significant difference in the lesion size between powers (P = 0.0064). There was no difference in the short-axis, but a significant difference in the lesion size between powers (P = 0.0306). A significant difference in the width of the transitional zone (TZ) was noticed between powers 50W and 90W (P= 0.015). Conclusion: CEUS shows better demarcation of the ablated zone when compared with the greyscale-US, a finding that could provide guidance in the assessment of the ablation zone during treatment. CEUS does not show superiority over morphology or grey-scale US in reflecting the actual size of the lesion. Histology remains the only method to provide exact measurements of the transitional zone width when compared with morphology. Further research is required to confirm these results.
HEALTH-PROMOTING BEHAVIORS IN PERSONS ADMITTED TO THE HEALTH CENTER SELECTED IN TEHRAN

Health-promoting behaviors in people admitted to selected health centers in Tehran. The significance of health-promoting behaviors in maintaining people's performance and independence and promoting the quality of life increases with age. This analytical cross-sectional study was conducted to determine health-promoting behaviors in people admitted to selected health centers in Tehran in 2010. In this study, 612 people (239 men and 373 women) admitted to Tehran's selected health centers were selected purposefully. The data were collected using "HealthPromoting Lifestyle Profile II. " This standard instrument consists of 6 subscales namely, nutrition, physical activity, spiritual growth, health responsibility, interpersonal relations, and stress management. To maintain weight of the items, the total scores of the instrument and subscales were calculated using mean scores. To do so, each item was assigned a score of 1-4. The independent t test and Pearson correlation coefficient were used to analyze the data. The spiritual growth and physical activity subscales comprised the maximum and minimum mean scores, respectively. The health responsibility and physical activity showed the maximum significant correlation, and the physical activity and the interpersonal relations scores showed the minimum significant correlation. The physical activity and health responsibility subscales got minimum scores. This necessitates the health care staff and authorities to pay more attention to these two subscales and take action to obviate or reduce these problems.
MUSCULOSKELETAL DISORDERS AND DISEASES IN FINLAND

Out of a nationally representative sample of 8,028 persons aged 30 years and over, 80% participated in a comprehensive health examination which included a standard clinical examination by a physician. Using standard criteria based on medical history, symptom history and physical status, chronic low-back syndrome was diagnosed in 10.8% of men and 11.0% of women, neck syndrome in 5.7% of men and 7.3% of women, hip osteoarthritis in 5.5% of men and 4.6% of women, knee osteoarthritis in 6.1% of men and 8.3% of women, and rheumatoid factor positive polyarthritis in 0.3% of men and 0.7% of women. In comparison with the Mini-Finland health survey carried out 20 years earlier, the prevalence of low-back and neck syndromes was found to have decreased in both sexes; the prevalence of knee osteoarthritis had decreased in women but not in men. Quantitative ultrasound measurements made at the heel showed that low bone density is common in the Finnish population, whereas the prevalence of self-reported osteoporosis is low and the prevalence of those being monitored by a doctor due to their osteoporosis is even lower. The length of education was inversely associated with the prevalence of common musculoskeletal syndromes. Self-rated disability at work and during leisure time was strongly associated with the presence of musculoskeletal disorders or diseases. A musculoskeletal disease or complaint was the principal reason for the most recent visit to a physician in 12% of Finnish adults, which indicates the proportion of all the visits attributable to this disease group. In addition to public registers and national interview surveys, repeated health examination surveys are necessary for studying the prevalence of common musculoskeletal disorders and for monitoring their development.
COMMENT REPORT OF THE CLAY MINERALS SOCIETY NOMENCLATURE COMMITTEE FOR 1982 AND 19831

1. The report of this committee for 1980-81 (Bailey et aL, 1982) with respect to the recommended nomenclature for regular interstratifications of Clay minerals has been approved without change by the International Mineralogical Association Commission on New Minerals and Mineral Names. 2. The committee recommends the name hydrobiotite for a regular 1:1 interstratification of biotite and vermiculite, as reported by Brindley et al. (1983). 3. The committee recommends that the approved species names for regular interstratifications should only be used by authors if the full requirements of the committee for regularity have been satisfied. For interstratified clays regular enough to meet the requirement that the coefficient of variation (CV) the d(00/) values is equal to or less than 0.75, it is permissible to state that the clay is, for example, rectorite-like or of the rectorite type, if the following conditions are satisfied: (a) tests have been carded out to determine the nature of the component layers; and (b) at least three orders of a superlattice spacing (including two odd orders) have been observed. Terminology of this sort may be useful for pure specimens where CV > 0.75 or for impure specimens where CV cannot be calculated due to overlap of peaks. Less regular specimens should be termed mica/smectite irregular interstratifications, etc. It is always desirable to characterize these clays in as much detail as possible. 4. Discussion is continuing as to the nomenclature of interstratifications that deviate by more than 5% from the ideal l: 1 ratio and as to criteria for regularity ofinterstratifications in other than 1:1 ratios (e.g., as in "tarasovite").
The Effect of Cross Year Peer Tutoring in Pharmacy Dispensing Classes: The Wolverhampton Experience

Background: Peer tutoring has been used as an educational tool for sometime in undergraduate healthcare teaching. However, in pharmacy, this approach appears not to have been reported in the literature. Aims: To gauge student opinion on a cross year peer tutoring scheme that involved senior peers (final year students) facilitating academic staff in first year dispensing classes. Method: Ten fourth year students volunteered to facilitate first year dispensing classes. Fourth year students were briefed as to their role and each student was involved in a minimum of two dispensing classes. After the final dispensing class had taken place both first and fourth year student opinion was sought on their experiences via online questionnaires. Results: Both first and fourth year students were very positive about their experiences. First year students learnt from their peers and were able to relate to see how they might themselves develop. Fourth year students benefitted by being able to reinforce skills and knowledge and used the experience as a means of reflection, which helped them realise how they had developed and gave them more confidence in their ability. Both sets of students had empathy toward each other. This was most apparent with regard to first year students feeling more at ease asking questions of their peers rather than academic staff. Conclusion: The peer tutoring scheme used in dispensing classes was seen by both tutees and tutors as beneficial.
Colostomy in Children: Indications and Complications

Objective: To determine the indication and frequency of complications occurring with construction of colostomy in children. Methodology: This descriptive study was conducted at Paediatric Surgery department of PMC Hospital and at Mumtaz Medical Center (Pvt.) Nawab Shah, from April 2008 to December 2009. All patients who required colostomy as the part of management were included in this study. The patients who were operated upon previously or elsewhere and were referred after having colostomy, were excluded. In all patients loop colostomy was performed. Complications after colostomy construction were noted on a proforma. Results: Thirty- seven colostomies were created in 36 patients. Sigmoid loop colostomies were 51.35%, Right and left transverse colostomies in 24.32% each. All patients were operated due to congenital anomalies. Twenty-eight patients had anorectal malformation and 8 Hirschsprung’s disease. Common Complications related to stoma were excoriation of skin 58.82% and prolapse of stoma (50%). Anaemia due to chronic blood loss was seen in 53.33% of patients. Transverse loop colostomy had higher number of complications / problems as compared with sigmoid loop colostomy. Five (13.88%) patients died (Three because of septicaemiae, one because of high grade fever at home, and one died on 2 nd of PSARP, the cause could not be ascertained. Conclusion: Construction of colostomy in paediatric patients carries high frequency of complications and requires careful technique. A sigmoid loop colostomy is an ideal as it has minimal complications. Stoma care clinic and enterostomal therapist can be helpful in educating families for stoma care and to decrease the incidence of complications.
Population Ecology and Evaluation of Suppression Scenarios for Introduced Utah Chub

Introduced Utah Chub Gila atraria were ﬁ rst sampled in Henrys Lake, Idaho, in 1993, and their presence in the system is a concern given possible interactions with sport ﬁ shes. Our objective was to describe the population dynamics of Utah Chub in Henrys Lake. A total of 362 Utah Chub was sampled via gill nets, with an average catch rate of 20.5 ﬁ sh / net-night (SE = 6.0) during May 2016. Average TL was 210 mm (SE = 3), and average weight was 134 g (SE = 5). Pectoral ﬁ n rays were used to provide estimates of growth and age structure. Utah Chub varied in age from 2 to 12 years, and recruitment was stable (recruitment coef ﬁ cient of determination = 0.96). Estimated total annual mortality was 40% (SE = 4%). Fecundity of Utah Chub in Henrys Lake increased with length and varied from 6,232 to 156,797 eggs / female. Age-structured population models were constructed using the demographics data, and estimated average population growth rate over a 10-year period was 1.17. This study provides a comprehensive descrip- tion of Utah Chub population dynamics and insight on their management in systems where they are not native. This information is not only useful for guiding management actions but also serves to further our understanding of Utah Chub ecology.
A study of Eggplant Leaf Spot Disease in Greenhouses at Basrah Province

The present study has been conducted to isolate and identify the leaf fungal spot pathogens of eggplant at different regions of Basrah city and their chemical control. The results showed that the disease was spread at all regions cultivated with eggplant at Basrah province with infection percentages of 46.6-88.5%. The highest infection percent was recorded at Garmat Ali region (88.5%), while the lowest percent was recorded at the Agricultural station (46.6%). The highest percent of disease severity (50 %) was recorded at Tomato Cultivars Breeding Project, while the lowest percent was recorded at Agricultural station (20%). Alternaria alternata, Cladosporium oxysporum and Curvularia lunata were isolated from the leaves infected with spot disease, the pathogenicity test revealed that all isolated fungi were pathogenic. C. oxysporum and C. lunata were recorded for the first time in Iraq as causal agents of eggplant leaf spot. The results showed that the fungicide Ortiva inhibited the growth of the fungi with an average of 95.7%, followed by Difecor ( 94.9%), additionally, it was noticed that all examined fungicides completely inhibited the growth of both C. oxysporum and C. lunata ( %100 for each one). The study revealed that the fungicide Ortiva significantly reduced the disease severity of eggplant leaf spot disease up to 11.6% compared with control treatment which was 25%. Finally the results explained that the fungicide Ortiva gave the best protection to eggplant which infected with leaf spot disease compared to the other fungicides, it achieved a best plant height, higher dry weight of shoot and root systems, higher leaf area and higher leaves number. Therefore it is recommended for controlling the spot disease.
Testing the basic tenet of the molecular clock and neutral theory by using ancient proteomes

Early research on orthologous protein sequence comparisons by Margoliash in 1963 discovered the astonishing phenomenon of genetic equidistance, which has inspired the ad hoc interpretation known as the molecular clock. Kimura then developed the neutral theory and claimed the molecular clock as its best evidence. However, subsequent studies over the years have largely invalidated the universal molecular clock. Yet, a watered down version of the molecular clock and the neutral theory still reigns as the default model for phylogenetic inferences. The seemingly obvious tenet of the molecular clock on evolutionary time scales remains to be established by using ancient sequences: the longer the time of evolutionary divergence, the larger the genetic distance. We here analyzed the recently published Early Pleistocene enamel proteome from Dmanisi and found that ancient proteins were more distant to an outgroup than their orthologs from extant sister species were. The results are completely unexpected from the molecular clock but fully predicted by the notion that genetic distances or diversities are largely at optimum saturation levels as described by the maximum genetic diversity (MGD) theory.
Determining the diet of an African mesocarnivore, the caracal: scat or GPS cluster analysis?

The caracal Caracal caracal is the largest of Africa's small felids (<20 kg). Across much of Africa, particularly where larger predators have been extirpated, caracal are one of the main carnivores contributing to livestock predation. Caracal dietary studies are outdated, typically have small sample sizes and have mainly relied on scat analysis. We used a combination of scat analysis (n = 250 scats) and GPS cluster visitation (n = 458 clusters visited; n = 91 clusters with feeding events) to estimate caracal diet in South Africa's Succulent Karoo, a global biodiversity hotspot. Based on both methods, rock hyrax Procavia capensis was the caracal's main prey. Small mammals accounted for 25.3% of total biomass consumed by caracal using scat analysis, however, were absent based on GPS cluster investigations. Domestic sheep Ovis aries biomass consumed was much higher (59.5%) when inferred from GPS cluster visitation than from scats (5%). Wild medium-to-large mammalian prey had little variation between the two methods. GPS telemetry did not enable detection of small prey (<1 kg) and possibly over-represented large prey items, including livestock. Scat analysis provided a broader representation of caracal diet, but scat investigations could have underestimated larger prey since caracals ingest only small amounts of hair from large-bodied animals. We recommend a combination of GPS cluster visitation and scat analysis to determine the diet of caracal and other mesocarnivores across a range of prey sizes.