Miracle-dz/UniFAR-FTUs huggingface dataset:
Interprofessional Team-based Learning: Building Social Capital

Often the first-time health professionals work together is as new graduates, with a paucity of shared learning among the various health disciplines within university curricula. This is largely due to the complexities of delivering interprofessional education (IPE) and the preference of individuals to work within their established silos. With its ability to nurture collaboration among students, there is a developing trend to use team-based learning (TBL) as a teaching method to engage health care students in IPE. Using the conceptual lens of social capital theory, the purpose of this article is to provide readers with an overview and evidence for the use of TBL within the interprofessional health care education setting, highlighting the benefits and challenges.
Prevention and Killing Efficacy of Carbapenem Resistant Enterobacteriaceae (CRE) and Vancomycin Resistant Enterococci (VRE) Biofilms by Antibiotic-Loaded Calcium Sulfate Beads

Carbapenem-resistant Enterobacteriaceae (CRE) and vancomycin-resistant Enterococci (VRE) have emerged as multidrug-resistant (MDR) pathogens associated with periprosthetic joint infections (PJI). In this study, we evaluated the efficacy of antibiotic-loaded calcium sulfate beads (ALCSB) in inhibiting bacterial growth, encouraging biofilm formation and killing preformed biofilms of CRE and VRE. Three strains of Klebsiella pneumoniae (KP) and a strain of Enterococcus faecalis (EF) were used. ALCSB of 4.8-mm diameter were loaded with vancomycin (V) and gentamicin (G), V and rifampicin (R), V and tobramycin (T) or R and meropenem (M), and placed onto tryptic soy agar (TSA), spread with one of the test strains and incubated for 24 h at 37 °C. Beads were transferred daily onto fresh TSA spread plates and the zone of inhibition (ZOI) was recorded until no inhibition was observed. ALCSB containing R + M or R + V produced the most extensive ZOI up to 5 weeks. Biofilm prevention efficacy was investigated by challenging ALCSB daily with 5 × 105 CFU/mL bacterial cells and analyzing for biofilm formation at challenges 1, 2 and 3. In the biofilm killing experiments, ALCSB were added to pre-grown 3-day biofilms of KP and EF strains, which were then analyzed at days 1 and 3 post-exposure. The CFU counts and confocal images of the attached cells showed that ALCSB treatment reduced colonization and biofilm formation significantly (5–7 logs) with combinations of R + M or R + V, compared to unloaded beads. This study provides evidence that the local release of antibiotics from ALCSB may be useful in treating the biofilms of multidrug-resistant strains of CRE and VRE.
Demographic, Social, and Economic Factors of Internalizing Problems in Referred and Non-Referred Adolescents

Depressive symptoms and suicidal ideation are common internalizing problems during adolescence. Numerous studies have explored the role of certain demographic, social, and economic factors in their development in referred or non-referred adolescents, but not simultaneously in both groups. In this study, we examined the association between age, gender, parents’ educational level, and socioeconomic status (SES) and depressive symptoms and suicidal ideation in a referred group (n = 211) and a non-referred (n = 1401) group of adolescents. We also examined the moderating role that these factors play in the relationships between both internalizing problems. The results showed: higher levels of depressive symptoms and suicidal ideation in the referred group; an increase in both problems during early-to-middle adolescence in the non-referred group; an association between low SES and suicidal ideation in both groups; an association between low father’s education level and depressive symptoms in the non-referred group; and no gender differences in either of these two internalizing problems. The moderation analyses showed that age, in referred adolescents, and SES, in non-referred adolescents, moderated the relationship between depressive symptoms and suicidal ideation. This study contributes to the identification of groups of vulnerable adolescents that could constitute the target populations of preventive programs.
Association of polymorphism genes LPL, ADRB2, AGT and AGTR1 with risk of hyperinsulinism and insulin resistance in the Kazakh population

Hyperinsulinism and insulin resistance are closely associated with several common diseases including type 2 of diabetes, cardiovascular diseases, and metabolic syndrome. The present study aimed to determine the association between hyperinsulinism, insulin resistance and the polymorphism of genes, including angiotensin II receptor type 1 (AGTR1), angiotensinogen (AGT), β2-adrenoreceptor (ADRB2) and lipoprotein lipase (LPL), in the Kazakh population. The design of the current research was a case-control study, involving 460 subjects (age range, 18-65 years). For every subject, plasma glucose, insulin, total cholesterol, triglycerides, high-density lipoprotein, low-density lipoprotein, apolipoprotein B and apolipoprotein A1 were examined. Moreover, reverse transcription-quantitative PCR was conducted to detect the polymorphism genes LPL Ser447Ter, ADRB2 Gln27Glu, AGT Thr174Met and AGTR1 A1166C. Hyperinsulinism was considered when the insulin level was elevated >24.9 IU/ml. The homeostasis model assessment insulin resistance (HOMA-IR) was used to evaluate insulin resistance. The subjects were divided into hyperinsulinism (17 men and 24 women) and normal level insulin (214 men and 205 women) groups, which were also split into insulin resistance group (HOMA-IR >2.7; 80 men and 105 women) and those without insulin resistance group (151 men and 124 women). The results suggested that LPL Ser447Ter (rs328) allele G was associated with a lower risk of hyperinsulinism (P=0.037). Furthermore, polymorphisms of genes ADRB2 Gln27Glu (rs1042714), AGT Thr174Met (rs4762) and AGTR1 A1166C (rs5186) were not associated with hyperinsulinism and insulin resistance in the Kazakh population. No interaction was identified between LPL Ser447Ter, ADRB2 Gln27Glu, AGT Thr174Met and AGTR1 A1166C. Therefore, the results indicated that haplotype combinations were not associated with insulin resistance.
Site-Of-Care Viscoelastic Assay in Major Trauma Improves Outcomes and Is Cost Neutral Compared with Standard Coagulation Tests

Major hemorrhage is often associated with trauma-induced coagulopathy. Targeted blood product replacement could achieve faster hemostasis and reduce mortality. This study aimed to investigate whether thromboelastography (TEG®) goal-directed transfusion improved blood utilization, reduced mortality, and was cost effective. Data were prospectively collected in a U.K. level 1 trauma center, in patients with major hemorrhage one year pre- and post-implementation of TEG® 6s Hemostasis Analyzers. Mortality, units of blood products transfused, and costs were compared between groups. Patient demographics in pre-TEG (n = 126) and post-TEG (n = 175) groups were similar. Mortality was significantly lower in the post-TEG group at 24 h (13% vs. 5%; p = 0.006) and at 30 days (25% vs. 11%; p = 0.002), with no difference in the number or ratio of blood products transfused. Cost of blood products transfused was comparable, with the exception of platelets (average £38 higher post-TEG). Blood product wastage was significantly lower in the post-TEG group (1.8 ± 2.1 vs. 1.1 ± 2.0; p = 0.002). No statistically significant difference in cost was observed between the two groups (£753 ± 651 pre-TEG; £830 ± 847 post-TEG; p = 0.41). These results demonstrate TEG 6s-driven resuscitation algorithms are associated with reduced mortality, reduced blood product wastage, and are cost neutral compared to standard coagulation tests.
Feeding behavior and productive performance of steers fed pearl millet grain-based diets containing proportions of babassu mesocarp bran

The objective of this study was to evaluate the feeding behavior and feedlot productive performance of dairy-origin steers fed for 84 days ground pearl millet grain-based diets with 0, 120, 240, 360, and 480 g kg-1 of babassu mesocarp bran (BMB) and a standard diet based on ground corn. Thirty Holstein-Zebu steers with average initial body weight of 371.02±27 kg were used. The experimental design was completely randomized, with five replications. Dry matter intake showed better fit with the quadratic regression equation with the inclusion of BMB, reaching a maximum value in diets with 360 g of this by-product. There was no difference for dry matter intake between pearl millet- and corn-based diets. There was no difference in total digestible nutrients intake between diets. The digestibility coefficient of organic matter decreased linearly with the increase in the dietary level of BMB. The digestibility coefficient of organic matter was not different between corn and millet diets. There was no difference in feeding time between diets. Total requirement of metabolizable energy increased linearly with inclusion of BMB. However, total requirements of metabolizable energy did not differ between the corn- and pearl millet-based diets. Average daily gain decreased linearly with the increase in BMB, with adjustment forced by the sharp decline of this variable in diets with 480 g of BMB. There was no difference in average daily gain between corn- and pearl millet-based diets. The inclusion of levels above 360 g of babassu mesocarp bran in pearl millet-based diets reduces the supply of metabolizable energy and the productive performance of feedlot dairy steers.
Crystal structure of 1-ferrocenyl-2-(4-nitrophenyl)ethyne

The title ferrocene derivative including an alkyne and a para-nitrophenyl substitution crystallizes in the P21/n space group. In the ferrocene unit, the pentadienyl (Cps) rings are in an eclipsed conformation. Strong intermolecular π–π-stacking, CH(Cp)—C(Cp), and O(p-nitrophenyl)—HC(Cp) interactions consolidate the crystal structure.
Bidirectional Influence of the COVID-19 Pandemic Lockdowns on Health Behaviors and Quality of Life among Chinese Adults

Background: The coronavirus disease 2019 (COVID-19) pandemic has created challenges that have caused profound changes in health behaviors. This study aimed to explore how COVID-19 is affecting the health-related quality of life (QoL) among Chinese adults. Methods: The data of health-related behaviors and QoL were collected via online surveys from 2289 adults (mean age = 27.8 ± 12 years) who had been isolated at home for an average of 77 days. Results: More than 50% of the respondents reported that their time engaged in daily physical activity (PA) decreased, while sedentary behavior (SB) time increased compared with that before the lockdown. Only 20% of the respondents reported engaging in moderate-to-vigorous PA, 23% of adults reported changed their diets to be healthier, and 30% reported consuming more vegetables, fruits, and milk products than before home-isolation. During home-isolation, 75.2% of the adults rated their sleep quality as very good, and 65% reported that they were satisfied with their QoL. Sleep quality mediated the relationship between PA and QoL. Conclusion: The two-to-three-month home-isolation has had mixed effects on adult health behaviors in China. The participants were found to have focused more on their eating quality and patterns, which had a positive influence on their QoL. However, people should be encouraged to exercise at home with limited space to maintain a generally healthy lifestyle during a prolonged quarantine.
Expression profile and association analysis of the porcine DQB1 gene with peripheral blood T lymphocyte subsets

Major histocompatibility complex (MHC) class II molecules play an important role in immunology by presenting antigens to T lymphocytes. As a key member of the MHC class II gene family, the DQB1 gene is involved in interacting with T cells in immune reactions. This study was designed to screen variations in exon 3 of the DQB1 gene in Large White, Landrace and Songliao Black pigs, and to investigate the association between DQB1 gene polymorphisms and peripheral blood T lymphocyte subsets in Large White samples. In addition, the spatial transcription profile of the DQB1 gene was examined, and the effect of gene polymorphisms on its mRNA level was further analyzed. One missense mutation in exon 3 of the DQB1 gene was first identified by DNA pool sequencing, and samples were genotyped by using the polymerase chain reactionrestriction fragment length polymorphism method. Statistical analysis indicated that the DQB1 genotype was significantly associated with CD4 ＋ CD8 － , CD4 － CD8 ＋ and CD4 ＋ /CD8 ＋ indexes (P 0.05). These results suggest that the DQB1 gene may be a promising candidate gene for porcine disease resistance.
Systematic analysis of enhancer and promoter interactions

Enhancer mapping has been greatly facilitated by various genomic marks associated with it. However, little is available in our toolbox to link enhancers with their target promoters, hampering mechanistic understanding of enhancer–promoter (EP) interaction. We develop and characterize multiple genomic features for distinguishing true EP pairs from noninteracting pairs. We integrate these features into a probabilistic predictor for EP interactions. Multiple validation experiments demonstrate a significant improvement over state-of-the-art approaches. Systematic analyses of EP interactions across 12 cell types reveal several global features of EP interactions: (i) a larger fraction
IAS Versus U.S. GAAP: Information Asymmetry–Based Evidence from Germany's New Market

Motivated by the debate about globally uniform accounting standards, this study investigates whether firms using U.S. generally accepted accounting principles (GAAP) vis-a-vis international accounting standards (IAS) exhibit differences in several proxies for information asymmetry. It exploits a unique setting in which the two sets of standards are put on a level playing field. Firms trading in Germany's New Market must choose between IAS and U.S. GAAP for financial reporting, but face the same regulatory environment otherwise. Thus, institutional factors such as listing requirements, market microstructure, and standards enforcement are held constant. In this setting, differences in the bid-ask spread and share turnover between IAS and U.S. GAAP firms are statistically insignificant and economically small. Subsequent analyses of analysts' forecast dispersion, initial public offering underpricing, and firms' standard choices corroborate these findings. Thus, at least for New Market firms, the choice between IAS and U.S. GAAP appears to be of little consequence for information asymmetry and market liquidity. These findings do not support widespread claims that U.S. GAAP produce financial statements of higher informational quality than IAS. Copyright 2003 The Institute of Professional Accounting, University of Chicago.
Competitive pressure and labor productivity: world iron ore markets in the 1980s

Does the extent of competitive pressure industries face influence their productivity? We study a natural experiment conducted in the iron ore industry as a result of the collapse in world steel production in the early 1980s. For iron ore producers, whose only market is the steel industry, this collapse was an exogenous shock. The drop in steel production differed dramatically by region: it fell by about a third in the Atlantic Basin but only very little in the Pacific Basin. Given that the cost of transporting iron ore is very high relative to its mine value, Atlantic iron ore producers faced a much greater increase in competitive pressure than did Pacific iron ore producers. In response to the crisis, most Atlantic iron ore producers doubled their labor productivity; Pacific iron ore producers experienced few productivity gains. ; This article originally appeared in the American Economic Review. (c) American Economic Association.
Invasive Alien Fish Species in Freshwater of the Continents

This review article presents the updated informationof freshwater Invasive Alien Species (IAS) of fishes of the continents to understand the homogenate progression in global freshwater ecosystems and the leading pathways of freshwater IAS fish introduction throughout the continents. North America contains 45 freshwater invasive fish species within 18 families, which is the most profuse off all other continents, whereas, Australia possesses the lowermost amount of freshwater IAS fish, 18 species under 8 families. Besides, Asia retains 41 freshwater IAS fish under 14 families and Europe acquires 32 species under 18 families. The uppermost spreader IAS fish family is Cyprinidae followed by Cichlidae subsequently. Nine common fishes ( Carassius auratus, Cyprinus carpio, Onchorynchus mykiss, Oreochromis mossambicus, Poecilia reticulata, Salmo salar, Salmo trutta and Salvelinusfontinalis) turned out invasive in all the continents (without Antarctica). Among IAS introduction pathways, aquaculture causes the highest percentage of freshwater IAS introduction in all continents. Aquaculture root 25% of IAS fish introduction in Africa, 21% in Asia, 19% in Australia, 20% in Europe, 19% in North America and 19% in South America. There is hardly any documentation on freshwater IAS fishes of Antarctica. Therefore, future research consideration may be designed. J. Environ. Sci. & Natural Resources, 8(2): 63-74 2015
Root characteristics of high-yield C Liangyou rice combinations of two-line hybrid rice.

【Objective】 The root characteristics of C Liangyou rice combinations and the correlation between root characteristics and yield were studied. 【Method】 The root morphology,root physiology as well as the correlation between root characteristics and yield were studied by using seven C Liangyou rice combinations as experimental materials and Shanyou 63 as a control. 【Result】 The results showed that root dry weight,number of adventitious root,total length of adventitious root,total root volume,root growth abilities,total root absorption area,root active absorption area and root oxidation ability of the combination were significantly higher than those of the control Shanyou 63.Root dry weight,number of adventitious root,total length of adventitious root,total root absorption area,and root oxidation ability at the heading stage,and root growth abilities at the grain filling stage and the milking stage had a significant positive correlation with yield per plant.Stepwise regression indicated that the number of adventitious root and root oxidation ability at the heading stage were the main influencing factors of high yield of rice and could be regarded as reliable indicators for cultivation and management and genetic inprovement of rice. 【Conclusion】 It is concluded that root morphology is good and the root is vigorous in C Liangyou rice combinations at all stages,its morphological and physiological characteristics ensure the efficient absorption of nutrient and water in the whole growing period,which is the base leading to high yield of C Liangyou rice combinations.Strong root vigor at the late growing stage,and proper ratio of root to shoot and the harmonious growth of root and shoot are also the main causes leading to high yield of C Liangyou rice combinations.
Completely Bounded Maps and Operator Algebras

1. Introduction 2. Positive maps 3. Completely positive maps 4. Dilation theorems 5. Commuting contractions 6. Completely positive maps into Mn 7. Arveson's extension theorems 8. Completely bounded maps 9. Completely bounded homomorphisms 10. Polynomially bounded operators 11. Applications to K-spectral sets 12. Tensor products and joint spectral sets 13. Operator systems and operator spaces 14. An operator space bestiary 15. Injective envelopes 16. Multipliers and operator algebras 17. Completely bounded multilinear maps 18. Applications of operator algebras 19. Similarity and factorization degree.
Bacillus atrophaeus Spore Survival on Netted Muskmelon Surfaces after Moist Heat Treatment

It has been reported that netted muskmelons (Cucumis melo var. cantalupensis) treated with moist heat (steam or hot-water immersion) have reduced populations of vegetative surface organisms that may be responsible for spoilage, or that may be pathogenic to consumers. It is unknown, however, what affect a similar heat treatment may have on infesting bacterial endospores (which are dormant, nonreproductive structures that are resistant to environmental stress). Also, any heat treatment used must be effective without exceeding the treated melon’s thermal damage threshold. In this study, natural microflora on muskmelon rind pieces treated from 75 to 95 C for 3 minutes and whole fruit rinds inoculated with Bacillus atrophaeus spores and treated at 85 C for 3 minutes were observed as a model system to explore the efficacy of moist heat in reducing surface populations of bacterial spores. There were significant reductions in populations of aerobic, nonspore-forming microbes, although the treatments had little to no effect on either the recoverable populations of inoculated B. atrophaeus spores or indigenous spore-forming bacteria. Recovery studies suggested a less than 2 log10 unit reduction of inoculated B. atrophaeus spores after a 3-minute, 85 C moist heat treatment, and no heat injury symptoms developed on melons during storage for 2 weeks at 5 C. Increasing treatment temperature from 75 to 95 C resulted in no increase in efficacy in terms of recovery of indigenous vegetative bacteria. The results of this study suggest that aqueous heat treatment is not a suitable method for reducing populations of the resting structures of spore-forming bacteria from the surface of netted muskmelons.
A Stage Model of Knowledge Management Systems Diffusion Process: Findings from an Australian Study

This study presents a stage model of knowledge management systems (KMS) diffusion process. It then provides empirical test of the sequence of KMS diffusion process in Australia. Structural equation modelling (SEM) using LISREL is used as the analytical tool for the empirical tests. The results show that all the hypotheses related to the sequence of the KMS diffusion process are significant. This is an important and significant finding. It clearly demonstrates how KMS adoption and diffusion phenomenon should be planned in Australian organizations. The results of the study add value to the literature of knowledge management. Also, the results provide practical and applicable suggestions to those companies, which are embarking on the adoption and diffusion of knowledge management system in Australia or elsewhere