Miracle-dz/UniFAR-FTUs huggingface dataset:
Incorporation of deuterated RRR- or all-rac-α-tocopherol in plasma and tissues of α-tocopherol transfer protein–null mice

BACKGROUND Most vitamin E supplements contain synthetic all-rac-alpha-tocopherol [2,5,7,8-tetramethyl-2RS-(4'RS,8'RS,12-trimethyltridecyl)-6-chromanol] with 8 stereoisomers; only 1 is identical to the natural stereoisomer, RRR-alpha-tocopherol [2,5,7,8-tetramethyl-2R-(4'R,8'R,12-trimethyltridecyl)-6-chromanol]. In humans, 2R-alpha-tocopherol stereoisomers are preferentially maintained in the plasma, a function that has been attributed to hepatic alpha-tocopherol transfer protein (alpha-TTP), but this hypothesis has not been tested. OBJECTIVE We sought to determine the functions of alpha-TTP by comparing mice that express alpha-TTP with mice that are genetically unable to express alpha-TTP. DESIGN Adult alpha-TTP null (Ttpa(-/-); n = 5), heterozygous (Ttpa(+/-); n = 7), and wild-type (Ttpa(+/+); n = 3) mice consumed equimolar RRR-alpha-[5,7-(C(2)H(3))(2)]-(d(6))- and all-rac-alpha-[5-(C(2)H(3))]-(d(3))-tocopheryl acetates (30 mg/kg diet each) for 3 mo. Subsequently, we measured labeled and unlabeled alpha-tocopherols in plasma and 17 tissues. RESULTS In all mice, plasma and tissue d(6)- + d(3)-alpha-tocopherols represented approximate 80-90% of total alpha-tocopherol. In the Ttpa(-/-) mice, low total alpha-tocopherol concentrations were found in plasma (5.4%) and most other tissues (2-20%), but liver concentrations were 39% of those of Ttpa(+/+) mice. Peripheral tissue ratios of d(6)- to d(3)-alpha-tocopherol were 1.1 plus minus 0.1 and 1.8 plus minus 0.2 in Ttpa(-/-) and Ttpa(+/+) mice, respectively (P < 0.0001), showing that alpha-TTP preferentially selects 2R-alpha-tocopherols for secretion into plasma. This 2:1 ratio does not support the currently defined international unit of 1.36:1 RRR-alpha-tocopherol to all-rac-alpha-tocopherol. CONCLUSION Deletion of the alpha-TTP gene in mice results in an accumulation of dietary alpha-tocopherol in the liver and depletion of peripheral tissue alpha-tocopherol.
Evaluation of the P16INK4a Expression in Cervical Biopsy Specimen SBMCH

In early 1980 human papillomavirus (HPV) were the risk factor and most commonly affects younger women. Many test have developed since then and among that a biomarker test system have developed and clinically evaluated. P16INK4a is used as an important marker for indicating neoplastic transformation for cervical dyplasia. This study was done to evaluate the P16INK4a expression in cervical biopsy in 50 cases. Two cases were identified a P16INK4a positive and remaining 48 didn’t show P16INK4a expression proving the hypothesis that p16INK4a is capable of showing the dysplasia positive cases.
The Europeanisation of Citizenship in the Successor States of the Former Yugoslavia (CITSEE) Lineages of Citizenship in Montenegro

This paper explores the evolution of citizenship policies in Montenegro. It employs Richard Bellamy's concept of the lineages of citizenship, which analyses the normative aspectsof citizenshipby lookingat interactions between 'stateand society within a given national political community'. In unveiling the processes and the context that shaped the Montenegrin citizenship policies at different times, the paper examines the active relationship between three major aspects of citizenship: legal, political and identity/emotional. Following a historical overview of the development of citizenship policies, this paper focuses on the recent political circumstances that have shaped the normative aspects of citizenship. As such, it also triggers questions about what layer of identity the citizenship legislation in fact encapsulates. The final part of the paper examines the multivalence of citizenship in the context of Europeanisation. Transiting 'the European route' has, in fact, recalibrated the relationship between the legal, political and emotional/identity aspects of citizenship in Montenegro.
METAL LEVELS IN COMMON SEAWEEDS FROM SUEZ BAY

Metal levels (Cd, Co, Cr, Cu, Mn, Fe, Pb, Ni and Zn) were determined in water and 24 species of seaweeds at 8 sites on Suez Bay close to the industrial and urban zone, from March 1998 through February 1999. The seaweeds of the Suez Bay contribute competently for elimination of trace metals from the water. The levels of metal in seawater were between 0.105 ppb for chromium and 20.76 ppb for zinc. In seaweed species, the levels were between 1.93 ppm for chromium and 1528.89 ppm for iron. Many species have high capacity for absorption of certain metals, making them good bioremediators. At the forefront, Cladophoropsis zollingeri (Chlorophyta) accumulated Cr, Fe, and Mn at 70, 112, and 306 times their levels in seawater. For Cd, Co, and Pb, calcareous algae such as Jania rubens, Halimeda tuna, and Galaxaura oblongata are good bioremediators. They accumulated 29, 32, and 34 times the levels measured in seawater.
Simulation of Water Stress and Climate Change Impacts on Canola Yield, Seed Quality and Water Productivity at North Delta, Egypt محاکاة تأثیرات تغیر المناخ والإجهاد المائی على محصول وجودة بذور الکانولا وانتاجیة وحدة المیاه فی شمال الدلتا، مصر.

A field trial was conducted at Sakha Experimental Research Station, Kafr El-Sheikh Governorate, Egypt during the two successive winter seasons of 2018/2019 and 2019/2020 to calibrate and validate the AquaCrop model (Version 5). Two cultivars of canola (Serw4 and Serw6) were sown to study the influence of two irrigation regimes (50 and 70% of soil moisture depletion SMD). Then, AquaCrop model was calibrated using the dataset of 1st season and validated using the 2nd season dataset by different statistical indicators i.e. coefficient of determination (R2) and degree of agreement (d). Also, the simulation of climate change impact on canola yields was done. Results show that mostly, irrigation at 50% depletion from soil moisture gives higher values of seed and biomass yields (Mg ha-1) and canola water productivity compared to 70% depletion from soil moisture. This trend is found with both canola cultivars but the Serw4 records values better than Serw6. Also, results show that AquaCrop model (Version 5) is able to simulate well seed and biomass yield of canola cultivars as well as canola water productivity under different irrigation treatments at the studied region, where, values of R2 and d record a robust agreement among predicted and observed values. As for the simulation of climate change influence, the findings indicate that increasing temperature leads to increasing the reduction percentage of seed yield of different canola cultivars, and the reduction percentage with Serw6 was more than Serw4.
Prospects for Evaluating the Damageability of Asphalt Concrete Pavements During Cold Recycling

The article considers improvement of the methodology for accounting for the degradation of asphalt concrete working in the upper layers of the pavement. Development of recycling technologies for road structures is an ongoing process; it allows reaching a higher quality of reclaimed materials and using them for subsequent construction of structural layers, including the upper layers without the protective ones, as well as during repair and reconstruction of roads of various technical categories. At the same time, the system of pre-project assessment (diagnostics) of the state of asphalt concrete pavements cannot be considered optimal and effective because the determined indicators demonstrate that, firstly, various surface and structural defects are present, and, secondly, that the indicators mentioned above are more relevant to the road structure as a whole. The joint handling of the theoretical and experimental data allows concluding that damageability level depends on the physical, mechanical and structural properties, the main being maximal structural strength and the number of elastic bonds involved in the deformation process. A variant of modelling of asphalt concrete damageability depending on the work capacity is proposed, when the reduced amount of dissipated energy is replaced with sufficient accuracy for practice by the ratio of the actual number of load application cycles (freezing and thawing cycles) to the limit. A correlation between the level of damageability and the kinetics of changes of the interpore space of asphalt concrete under the influence of strain (temperature, climatic factors) has been established. Results allow fixing (predicting) the level of damageability by measuring the level of water permeability. The research methodology and equipment for implementation thereof was developed earlier, it can be effectively used at the stage of pre-project diagnosis.
Diversification of Fads2 in Finfish Species: Implications for Aquaculture

The capabilities for biosynthesis of long-chain (≥C20) polyunsaturated fatty acid (LC-PUFA) of farmed fish have been extensively studied in order to determine qualitative requirements for dietary essential fatty acids and to ensure high levels of omega-3 LC-PUFA in the farmed products for human consumption. Although LC-PUFA biosynthesis comprises multiple steps catalyzed by several enzymes, rate-limiting reactions in the pathways are controlled by fatty acid desaturases (Fads), enzymes introducing new double bonds into fatty acyl chains. The repertoire of Fads-encoding genes varies among vertebrates. Mammals have two FADS with known roles in the LC-PUFA biosynthetic pathways, namely FADS1 with Δ5 desaturase activity and FADS2 with Δ6 activity. Interestingly, teleosts, the fish group which most farmed species belong to, appear to have lost fads1 during evolution and therefore Fads2 is the sole enzyme able to account for the desaturation reactions in the LC-PUFA pathway in teleosts. Unlike mammals though, functions of teleost Fads2 have diversified remarkably as a result of species-specific evolutionary history and environmental factors including habitat (marine vs freshwater), trophic level and ecology. This paper reviews the recent progress made on molecular aspects underlying the functional diversity of Fads2 characterized so far from finfish species. Specifically, we discuss the potential implications that Fads2 functions have for the ability of fish species to efficiently utilize dietary fatty acids when fed on vegetable oilbased feeds. In addition, current developing technologies including genetic approaches (e.g. transgenesis) to improve the LC-PUFA biosynthetic capability of fish are discussed.
Antibacterial activity of Securidaca longipedunculata stem bark against some clinical bacterial isolates

Securidaca longipedunculata is a multipurpose plant with a long history of use in Nigerian and African traditional medicine. The present study was aimed to investigate the antibacterial activity of the aqueous stem bark extract of this important plant against clinical isolates of Escherichia coli, Salmonella typhi, Staphylococcus aureus, Shigella dysenteriae, Pseudomonas aeruginosa and Klebsiella pneumoniae. The result shows that the extract was active against all the tested bacterial isolates; the highest activity was recorded against Staphylococcus aureus (36 mm) and lowest activity against Shigella dysenteriae (24 mm). The minimum inhibitory concentration was observed within the range of 2.5-5 mg/ml, while the minimum bactericidal concentration was observed within the range of 5-10 mg/ml. The phytochemical screening revealed the presence of anthraquinones, saponins, phenolic compounds, carbohydrates, glycosides, steroids, terpenoids, alkaloids and flavonoids. The study has supported the use of this plant in the management of bacterial diseases and could serve as a potential source of antibacterial drugs of plant origin.
Foreign Capital, Real Sector Financing and Excessive Leverage in Turkey: What Went Wrong?

Recently, large swings in inflation and exchange rates revealed that non-financial sector is heavily geared and extremely vulnerable. Therefore, a study trying to identify the contributing factors is needed. Separating firms into groups, based on size and stock market trading status; changes in financing patterns are investigated via panel data methodology. The study aims at fulfilling the need for analyzing the consequences of foreign capital flow at firm level and documenting its significance in addition to assessing the efficacy of contemporary monetary policy. Economic conditions significantly facilitated lending process, strengthening corporate access to credit, and resulted in excessive borrowing both in the form of foreign and domestic currency. With such heavy burden of debt, non-financial sector has been facing both exchange rate and the liquidity risks. The more severely a firm was previously challenged by financing limitations, the more it borrowed once the limitations are relaxed, contributing to excessive debt burden of the economy in proportion to its previous financing challenges.
THE CHEMICAL COMPOSITION OF DIFFERENT BARLEY VARIETIES GROWN IN LITHUANIA

The objective of the study was to evaluate the range variation in chemical composition and antinutritional factors of 6 spring and 6 winter barley varieties grown in Lithuania. Grain samples of different varieties were analysed for crude protein, crude fat, crude ash, crude fibre and β-glucans. The content of crude protein in spring barley varieties was higher than in winter varieties and ranged between 10.35% DM and 12.38% DM. Variety Michelle accumulated the highest content of crude protein. Content of crude fat in both spring and winter barley varieties ranged between 1.09% DM and 2.00% DM and crude ash ranged between 1.94% DM and 2.40% DM. The NFE content varied from 65.45% DM to 69.08% DM in the analysed varieties of barley. The mean β-glucan content was lower in spring barley samples (1.64% DM, ranging between 1.09% DM and 2.36% DM in different varieties), and in winter barley samples, it was 2.89% DM (ranging between 2.19% DM and 3.95% DM in different varieties). We found the high variation in β-D-glucan content within winter barley varieties, and the results indicate that varieties KWS Meridian and Lorely had the highest levels of β-D-glucan (> 3% DM). The present study showed considerable differences in chemical composition between spring and winter barley varieties grown in Lithuania. The winter varieties of barley accumulated the highest amount of β-glucan, as an antinutritional factor in nutrition of monogastric animals.
The effect of audit quality on analyst following

Abstract Analysts’ behavior is important, because they play a significant role in the capital market. Prior studies already show the effects of firm characteristics on analysts’ behavior, however, there was a lack of research analyzing the effects of audits on financial analysts’ behavior. Therefore, I examine the effect of audit quality on analyst following that is one of the most popular analysts’ behaviors. Higher quality audit makes the users of the financial reports more reliable, thus, this reliability makes analysts easier and more accurate to forecast earnings of that firm, then analysts are more likely to follow this firm. Using two different audit quality measures, results indicate that firms receiving high-quality audit services have more analyst following than others. These results show that audit quality is also one of the determinants of analyst following behavior.
Spatial and temporal dynamics of tomato mottle geminivirus and Bemisia tabaci (Genn.) in Florida tomato fields

Progression of tomato mottle geminivirus (TMoV), and abundance and dispersion of adult whitefly, Bemisia tabaci (Gennadius) B biotype, were monitored in 1992 and 1993 in 91 experimental plots located on 10 commercial tomato farms. Prior to harvest (73 to 75 days post plant) within-row aggregation of tomato mottle-infected plants was detected by means of ordinary runs analysis in only two of 14 plots that exhibited a disease incidence greater than 5%. At harvest (95 to 107 days post plant), within-row aggregation was detected in 11 of 21 plots. Significant clustering of diseased plants occurred in only 7% of plots analyzed with Gray's two-dimensional distance class analysis. The observed pattern of disease in these plots was characterized as having numerous small clusters of symptomatic plants scattered throughout plots prior to harvest. No relationship was observed between disease incidence and the degree of aggregation. Dispersion patterns of adult B. tabaci fluctuated throughout the season with values of the Morisita's index ranging from less than 1 (indicating a uniform dispersion pattern) to greater than 2 (indicating an aggregated pattern). Abundant sources of immigrating viruliferous whitefly vectors, rather than secondary spread within fields, appeared to be the driving force behind epidemics of tomato mottle in this production system characterized by frequent applications of insecticides.
Volumetric Traffic Count Survey And Statistical Analysis On Baraki Intersection Kabul Afghanistan

the current paper is evaluated the traffic characteristics which is vital for selecting an appropriate geometric design of pavement. The traffic data includes traffic volume, traffic speed, and the percentage of trucks or other large vehicles. Traffic volume is an important basis for determining what improvements, if any, are required on a highway or street facility. Traffic volumes can be expressed in terms of average daily traffic or design hourly volumes. These volumes must be used to calculate the service flow rate, which is typically used for evaluations of geometric design alternatives. This study was found the variability of traffic volumes by vehicle classification. It is discussed the traffic volume in terms of statistics. The purpose of this study is to demonstrate how to estimate daily traffic volumes in peak hours which is selected 3-hour-vehicles counts and also identifying, collecting the data, and analyzing it. This study has counted more than 12179 vehicles for 3 hours for each observation period is 15 min. It is distributed as follows; 9035 cars, 137 taxies, 1710 Light vehicle, 755 heavy vehicles, 86 bus, 456 minibusses. It is found the percentage of cars 75% in one location site and it is selected the highest percentage of vehicles.
INVESTIGATION OF THE INHIBITIVE PROPERTIES OF MANGIFERA INDICA (MANGO) SEED EXTRACT ON ALUMINUM METAL CORROSION IN 0.5M HCL MEDIUM

Mangifera indica (Mango) seed extract was examined as corrosion inhibitor for aluminum in hydrochloric acid medium. The inhibition properties of the extract were investigated using gravimetric method in the form of a prolonged period of experimentation (21 days) and a rapid period of experimentation (5 hours). Inhibitor concentration (0.2 g/L – 1.0 g/L) and time were the considered factors at ambient temperature. In the case of the prolonged test, variation of weight loss was monitored periodically in 0.5M HCl medium in the presence of the different concentrations of the inhibitor and its absence. The weight loss was calculated in grams as the difference between the initial weight and the weight after the removal of the corrosion product. In the rapid test case, air was introduced in the acidic medium and weight loss measurements also taken after the experiment. The concentration of extract with the highest inhibition efficiency for the prolonged test experiment was 0.4g/L, with an efficiency of 95.31% recorded while the highest inhibition efficiency value for the rapid test case was 93.68% recorded for the 1.0g/L concentration. However, most of the efficiency values obtained in the former were low compared with those obtained in the latter. This shows that Mangifera indica seed extract better inhibited the corrosion of aluminum in hydrochloric acid during the
IMPACTS OF COMPOST, BIOFERTILIZER AND/OR SOME ANTIOXIDANT TREATMENTS ON GLADIOLUS (GLADIOLUS GRANDIFLORAS) B. Corms and cormels production and some chemical constituents

Gladiolus is commercially propagated by its underground structure for production of flowers and corms as well as cormels. A field experiment was conducted during two successive seasons of 2018/2019 and 2019/2020 to investigate the effects of compost as an organic fertilizer (0, 5, 10 and 15 ton/fed) and Microbein biofertilizer (M.B.) at 50 ml/plant and/or some antioxidant treatments (salicylic and ascorbic acids) on corm and cormels production and chemical constituents of Gladiolus grandiflorus var. Jester plants. The obtained results indicated that corm diameter (cm), number of new cormels/plant, dry weight of corm and cormels (g), as well as, chemical constituents including chlorophyll a, b, carotenoids in the fresh leaves and percentages of N, P and K in the dry leaves were gradually increased by increasing levels of compost with significant differences. The highest corm diameter (5.27 cm) was produced by plants received compost at 15 ton/fed in combination with Microbein biofertilizer (M.B.) plus salicylic acid plus vitamin C while least size (2.5 cm) of corm was observed in control plants. All six treatments of Microbein biofertilizer (M.B.) at 50 ml/plant and/or some antioxidant (salicylic and ascorbic acids) treatments each at 50 ppm significantly increased corms and cormels production and the content of chemical constituents in comparison with control treatments. Treatments of Microbein biofertilizer (M.B.) plus salicylic acid plus ascorbic acid (vit. C) was more effective than other treatments for corm and cormels production, as well as, photosynthetic pigments content (mg/g. F.W.) and the percentage of nitrogen, phosphorus and potassium, in most cases. The interaction between compost, Microbein biofertilizer (M.B.) and/or some antioxidant (salicylic and ascorbic acids) treatments were significant for all previous characters. In some cases, the highest values of corms and cormels production were achieved by compost (15 ton/fed) in combination with Microbein biofertilizer (M.B.) plus salicylic acid plus ascorbic acid (vit. C) followed by 15 ton/fed compost with M.B. + vit. C then 10 ton/fed compost with M.B. + salicylic acid + vit. C which recorded the highest contents of pigments and elements of N, P and K.
Consumption of safe drinking water in Pakistan: its dimensions and determinants

Abstract. Safe drinking water is one of the basic human needs. Poor quality of drinking water is directly associated with various waterborne diseases. The present study has attempted to analyze the household preferences for drinking water sources and the adoption of household water treatment (HWT) in Pakistan by using the household data of Pakistan Demographic and Health Survey 2017–2018 (PDHS, 2018). This study found that people living in rural areas, those with older heads of household and those with large family sizes are significantly less likely to use water from bottled or filtered water. Households with media exposure, education, women's empowerment in household purchases and high incomes are more likely to use bottled or filtered water. Similarly, households are more likely to adopt HWT in urban areas, when there is a higher level of awareness (through education and media), higher incomes, women enjoy a higher level of empowerment, and piped water is already used. However, households that use water from wells and have higher family sizes are less likely to adopt water purifying methods at home.
Evaluation of MRR in ECDM Process with FEA

- Electro chemical discharge machining (ECDM) or Electro chemical spark machining (ECSM) or Electrochemical anode machining (ECAM) or Spark assisted chemical machining (SACM) is one of the non-conventional machining process. This process is predominantly used for machining electrically non conducting materials. ECDM is a hybrid process combination of both Electrical discharge machining (EDM) and Electro-chemical machining (ECM) the electrical discharge during machining results in major material removal while the chemical action results in minute material removal which helps in obtaining better surface finish. An attempt has been made to develop a finite element simulation model to evaluate material removal rate (MRR) in case of quart and the results are compared with the experimental results available to validate the model.