Miracle-dz/UniFAR-FTUs huggingface dataset:
Ertapenem Supplemented Selective Media as a New Strategy to Distinguish β-Lactam-Resistant Enterobacterales: Application to Clinical and Wastewater Samples

The increase in carbapenem-resistant Enterobacterales (CRE) is mostly driven by the spread of carbapenemase-producing (CP) strains. In New Caledonia, the majority of carbapenemases found are IMP-type carbapenemases that are difficult to detect on routine selective media. In this study, a culture-based method with ertapenem selection is proposed to distinguish non-CRE, non-CP-CRE, and CP-CRE from samples with very high bacterial loads. Firstly, assays were carried out with phenotypically well-characterized β-lactam-resistant Enterobacterales isolates. Then, this approach was applied to clinical and environmental samples. Presumptive CP-CRE isolates were finally identified, and the presence of a carbapenemase was assessed. In a collection of 27 phenotypically well-characterized β-lactam-resistant Enterobacterales, an ertapenem concentration of 0.5 µg·mL−1 allowed distinguishing CRE from non-CRE. A concentration of 4 µg·mL−1 allowed distinguishing CP-CRE from non-CP-CRE after nine hours of incubation. These methods allowed isolating 18 CP-CRE from hospital effluents, including the first detection of a KPC in New Caledonia. All these elements show that this cost-effective strategy to distinguish β-lactam-resistant Enterobacterales provides fast and reliable results. This could be applied in the Pacific islands or other resource-limited settings, where limited data are available.
Nowcasting Challenges during the Beijing Olympics: Successes, Failures, and Implications for Future Nowcasting Systems

Abstract The Beijing 2008 Forecast Demonstration Project (B08FDP) included a variety of nowcasting systems from China, Australia, Canada, and the United States. A goal of the B08FDP was to demonstrate state-of-the-art nowcasting systems within a mutual operational setting. The nowcasting systems were a mix of radar echo extrapolation methods, numerical models, techniques that blended numerical model and extrapolation methods, and systems incorporating forecaster input. This paper focuses on the skill of the nowcasting systems to forecast convective storms that threatened or affected the Summer Olympic Games held in Beijing, China. The topography surrounding Beijing provided unique challenges in that it often enhanced the degree and extent of storm initiation, growth, and dissipation, which took place over short time and space scales. The skill levels of the numerical techniques were inconsistent from hour to hour and day to day and it was speculated that without assimilation of real-time radar reflectivit.
Atmospheric gravity waves and aircraft turbulence encounters

Abstract We describe aircraft turbulence-atmospheric gravity wave events which occurred during a 2-day period over the Continental Divide. The waves are observed by two microbarograph networks an each side of the divide and last for several hours at a time. We show them to be unstable modes of the jet stream, corresponding to propagating internal gravity waves. We also show that the position of aircraft-reported turbulence coincides with the critical levels of the waves.
Volatility in the Turkish wholesale electricity market: an assessment

ABSTRACT Electricity prices are determined in wholesale markets. A major issue in determining prices is the distortive effect of high volatility of supply. This paper investigates the volatility of electricity supply in the Turkish energy exchange for the period between 2017 and 2020, by using hourly data. We find that volatility increased substantially during this period and uncertainty became a major issue. High volatility brings non-price variables such as institutional and political preferences to the forefront in terms of the decision-making of suppliers. We also discuss the dominance of bilateral contracts, the design of the renewable support mechanism, and the disappearance of independent traders in the wholesale market as some of the major issues that correlate with high volatility.
Mamma Mia! Revealing Hidden Heterogeneity by PCA-Biplot - MPC Puzzle for Italy’s Elderly Poor

I investigate consumption patterns in Italy and use a PCA-biplot to discover a consumption puzzle for the elderly poor. Data from the third wave (2017) of the Eurosystem’s Household Finance and Consumption Survey (HFCS) indicate that Italian poor old-aged households boast lower levels of the marginal propensity to consume (MPC) than suggested by the dominant consumption models. A customized regression analysis exhibits group di ff erences with richer peers to be only half as large as prescribed by a traditional linear regression model. This analysis has benefited from a visualization technique for high-dimensional matrices related to the unsupervised machine learning literature. I demonstrate that PCA-biplots are a useful tool to reveal hidden relations and to help researchers to formulate simple research questions. The method is presented in detail and suggestions on incorporating it in the econometric modeling pipeline are given.
First-principles investigations of the electronic structure and magnetocrystalline anisotropy in strained magnetite Fe 3 O 4

The electronic structure and magnetocrystalline anisotropy energy of strained fcc Fe 3 O 4 have been studied by using the linear muffin-tin orbital method within density functional theory. A uniaxial strain applied along the [001] direction of the magnetite is considered. It is found that the applied strain would initially reduce the calculated band gap of the majority spin and then turn the half-metallic behavior in the cubic limit into the normal metallic state at high in-plane strains of -1.3% and 2.1%. The calculated fourth-order anisotropy constant K 1 of cubic Fe 3 O 4 is in fair agreement with the experimental value. The magnitude of K 1 appears to be suppressed under large extensive lateral strains. The second order uniaxial anisotropy constant K o u t is positive for extensive in-plane strains and is negative for compressive in-plane strains. The positive value of K o u t minus the shape anisotropy indicates that an Fe 3 O 4 film under an extensive in-plane strain larger than 0.2% would show the perpendicular magnetization, in good agreement with recent experiments on Fe 3 O 4 films on MgO(100) and CoO(100). Interestingly, site decomposition shows that the A- and B-site Fe atoms in the strained magnetite have comparable anisotropy energies but with the opposite signs, while the oxygen's contribution is negligible. This implies that under an extensive lateral strain, the B-site irons would favor perpendicular magnetization while the A-site irons would prefer an in-plane magnetization. The total K o u t is dictated by that of the B-site irons due to their number being twice that of the A-site irons.
Global Sea Surface Temperature Prediction Using a Multimodel Ensemble

Abstract In a tier-two seasonal prediction system, prior to AGCM integration, global SSTs should first be predicted as a boundary condition to the AGCM. In this study, a global SST prediction system has been developed as a part of the tier-two seasonal prediction system. This system uses predictions from four models—one dynamic, two statistical, and persistence—and a simple composite ensemble method is applied to these models. The simple composite ensemble prediction system has predictive skill over most of the global oceans for up to a 6-month forecast lead time. The simple ensemble method is also compared with other more sophisticated ensemble methods. The simple composite method has forecast skill comparable to the other ensemble methods over the ENSO region and significantly better skill outside the ENSO region.
Methods for Assessing Spillover in Network-Based Studies of HIV/AIDS Prevention among People Who Use Drugs

Human Immunodeficiency Virus (HIV) interventions among people who use drugs (PWUD) often have spillover, also known as interference or dissemination, which occurs when one participant’s exposure affects another participant’s outcome. PWUD are often members of networks defined by social, sexual, and drug-use partnerships and their receipt of interventions can affect other members in their network. For example, HIV interventions with possible spillover include educational training about HIV risk reduction, pre-exposure prophylaxis, or treatment as prevention. In turn, intervention effects frequently depend on the network structure, and intervention coverage levels and spillover can occur even if not measured in a study, possibly resulting in an underestimation of intervention effects. Recent methodological approaches were developed to assess spillover in the context of network-based studies. This tutorial provides an overview of different study designs for network-based studies and related methodological approaches for assessing spillover in each design. We also provide an overview of other important methodological issues in network studies, including causal influence in networks and missing data. Finally, we highlight applications of different designs and methods from studies of PWUD and conclude with an illustrative example from the Transmission Reduction Intervention Project (TRIP) in Athens, Greece.
Effectiveness of Paliperidone Palmitate in Reducing Acute Psychiatric Service Use for Patients Suffering from Psychosis—A Retrospective Mirror-Image Study

Poor adherence to antipsychotic treatment is a leading cause of relapse for patients suffering from psychotic disorders and the use of long-acting injectable antipsychotics (LAI) may lead to improved clinical outcomes. This was a 1-year mirror-image study examining the clinical outcomes after monthly administration of paliperidone palmitate (PP1M). The primary outcome measure was the total days of psychiatric hospitalization in the 1-year before and 1-year after initiation of PP1M. Data from 158 patients were included in the study. Most of the patients suffered from schizophrenia. In the year after initiation of PP1M, the mean number of hospitalization days fell from 106.53 to 19.10 (p < 0.001). There were significant reductions in the mean number of hospitalizations and emergency room visits. The use of paliperidone palmitate is associated with significant reduction in both the number of admissions and days of psychiatric hospitalization.
Encapsulation of Orange Peel Oil in Biopolymeric Nanocomposites to Control Its Release under Different Conditions

Orange peel oil (OPO) is one of the most common flavorings used in the food industry, but it is volatile under environmental conditions (the presence of light, oxygen, humidity, and high temperatures). Encapsulation by biopolymer nanocomposites is a suitable and novel strategy to improve the bioavailability and stability of OPO and its controlled release. In this study, we investigated the release profile of OPO from freeze-dried optimized nanocomposite powders as a function of pH (3, 7, 11) and temperature (30, 60, and 90 °C), and within a simulated salivary system. Finally, its release kinetics modelling was performed using experimental models. The encapsulation efficiency of OPO within the powders, along with the morphology and size of the particles, were also evaluated by an atomic force microscopy (AFM) analysis. The results showed that the encapsulation efficiency was in the range of 70–88%, and the nanoscale size of the particles was confirmed by AFM. The release profile showed that the lowest and the highest release rates were observed at the temperatures of 30 and 90 °C and in the pH values of 3 and 11, respectively, for all three samples. The Higuchi model provided the best model fitting of the experimental data for the OPO release of all the samples. In general, the OPO encapsulates prepared in this study showed promising characteristics for food flavoring applications. These results suggest that the encapsulation of OPO may be useful for controlling its flavor release under different conditions and during cooking.
Development of a Digital-Preneurship Measurement Instrument: Alignment Approach Through Project-Based Learning

The purposes of this research are (a) to make an instrument to measure the achievement of project-based digitalpreneurship learning in students; (b) to describe the quality of the project-based digitalpreneurship learning achievement assessment instrument for vocational high school students; (c) to measure the competence and skills. This study employed to research and development as its methodology, using a combination procedure between Oriondo and Antonio and, Mardapi. The development procedure includes three stages: instrument design, instrument testing, and measurement. A total of 795 students who participated in the study at 5 vocational high schools in Yogyakarta's special region served as responders. Data analysis in this development uses the content validity of the formula Aiken V Index, confirmatory factor analysis establishes the construct's validity, and construct reliability. Measurement instrument development. Research findings that (a) the instrument is ready to be used in the measurement; (b) the quality of the project-based digitalpreneruship learning achievement assessment instrument for vocational high school students is well tested. This is evidenced by the validity test which has a high score >. 8; The proof of construct validity in this study using CFA > . 5; GOF chi-square value with a critical value of df = 289, X2 = 323, p-value with a critical value of . 079, RMSEA with a critical value of RMSEA . 019 (≤ .08), SMRM with a critical value of SRMR 0.030 (≤ .05), CFI with a critical value of CFI . 990 (> .97), and an NFI with a critical value of NFI . 989 ( > .90); (c) the measurement results are identified in the process that needs to be improved again regarding the digitalpreneurship skills of vocational high school students.
Platelet and ferritin as early predictive factors for the development of macrophage activation syndrome in children with Kawasaki disease: A retrospective case-control study

Objective To investigate the early predictive factors for Kawasaki disease complicated with macrophage activation syndrome (KD-MAS) Methods We performed a retrospective case-control study in children with KD from August 2017 to August 2022, involving 28 cases with KD-MAS and 112 cases not developing KD-MAS. Based on the univariate analysis, binary logistic regression was used to identify the early predictive factors for KD-MAS development, and the receiver operating characteristic curve (ROC) analysis was carried out to obtain the optimal cut-off value. Results Two predictive factors were associated with the development of KD-MAS, which were PLT (OR = 1.013, 95%CI, 1.001–1.026), and serum ferritin (OR = 0.991, 95%CI, 0.982–0.999). The cut-off value of PLT was 110 × 109/L, and the cut-off value of serum ferritin was 548.4 ng/ml. Conclusion Children with KD who had a PLT count under 110 × 109/L, and a serum ferritin level over 548.4 ng/ml are more likely to develop KD-MAS.
Physical activity and quality of life of patients with fibromyalgia

Background Fibromyalgia Syndrome (FMS) has been linked to decreased social functioning, poor mental health, and quality of life (QOL). Increased physical functioning and activity can result in improvements in social, mental and overall health, as well as lowered depression and anxiety levels. Objectives The aim of this study was to determine physical activity levels and QOL amongst patients diagnosed with fibromyalgia in the Johannesburg region of South Africa. Methods The research design was cross-sectional. Descriptive and quantitative data were collected. FMS patients (n=38) completed an online questionnaire on the Google Forms platform. The questionnaire was comprised of four components, namely Demographics, the Global Physical Activity Questionnaire (GPAQ), the Fibromyalgia Impact Questionnaire (FIQR), and the Short Form-36 (SF-36). During data analysis, descriptive characteristics and correlations were computed. The significance level was set at p ≤ 0.05. Results Results revealed high FIQR scores (67%) accompanied with low QOL scores (<50% in all domains). There was no correlation between physical activity and FIQR, and physical activity and QOL. Conclusion High scores on the impact of FMS were associated with lower overall QOL scores. However, the relationship between physical activity, and the impact of FMS and QOL remain inconclusive.
Functional Outcome Analysis of Stereotactic Catheter Aspiration for Spontaneous Intracerebral Hemorrhage: Early or Late Hematoma Evacuation?

Background: Minimally invasive stereotactic catheter aspiration becoming a promising surgical alternative for intracerebral hemorrhage (ICH) patients. Our goal is to determine the risk factors that lead to poor functional outcomes in patients undergoing this procedure. Methods: Clinical data of 101 patients with stereotactic catheter ICH aspiration were retrospectively reviewed. Univariate and multiple logistic analyses were used to identify risk factors for poor outcomes 3 months and 1 year after discharge. Univariate analysis was used to compare the functional outcome between early (<48 h after ICH onset) and late hematoma evacuation (≥48 h after ICH onset) groups, as well as for the odd ratios assessment in terms of rebleeding. Results: Independent factors for poor 3-month outcome included lobar ICH, ICH score > 2, rebleeding, and delayed hematoma evacuation. Factors for poor 1-year outcome included age > 60, GCS < 13, lobar ICH, and rebleeding. Early hematoma evacuation was linked to a lower likelihood of poor outcome both 3 months and 1 year post-discharge, but with higher risk of postoperative rebleeding. Conclusions: Lobar ICH and rebleeding independently predicted both poor short- and long-term outcomes in patients with stereotactic catheter ICH evacuation. Early hematoma evacuation with preoperative rebleeding risk evaluation may benefit patients with stereotactic catheter ICH evacuation.
Sigmis: A Feature Selection Algorithm Using Correlation Based Method

Feature Selection is one of the preprocessing steps in machine learning tasks. Feature Selection is effective in reducing the dimensionality, removing irrelevant and redundant feature. In this paper, we propose a new feature selection algorithm (Sigmis) based on Correlation method for handling the continuous features and the missing data. Empirical comparison with three existing feature selection algorithms using UCI data sets shows that the proposed system is very effective and efficient in selecting the feature set.
Students’ Knowledge Regarding Antibiotic Usage for Children Upper Respiratory Tract Infections

Upper respiratory tract infections are the most common illness among children under 5 years old. Knowledge regarding antibiotics usage is essential especially among pharmacy and nursing students. To assess students' knowledge regarding the use of antibiotics to treat children upper respiratory tract infection (URTIs). A cross-sectional study was conducted on 300 students collected from the College of Nursing and Pharmacy in a private university in Baghdad using convenience sampling. Data collection was done using an electronic platform. Around two-thirds (58.7%) of the students have a good level of knowledge. Only (41.3%) of students had poor knowledge about the use of antibiotics in children's upper respiratory tract infections. More than half (60.33%) of the students were aware of antibiotic resistance resulting from the overuse of antibiotics. There was a significant association between gender and Knowledge on antibiotics usage (P value=0.022). The students' knowledge regarding the use of antibiotics to treat children upper respiratory tract infection was good. More health promotions and educational campaigns are required to help students understand the correct use of antibiotics.
Domaines sans point critique intérieur sur l'espace projectif complexe

Introduction. En 1953, Oka [1[ a montre que tout domaine pseudoconvexe fini sans point critique interieur sur l'espace de n variables complexes est holomorphe-convexe. Ii a indique en chemin que Bans tout domaine de cette sorte, it existe une fonction pseudoconvexe ayant certaines proprietes.l' En 1962, Nishino [2[ a indique que d'apres une idee des methodes d'Oka, un espace analytique est holomorphiquement complet, s'il admet une fonction de Levi strictement positive et complete. Dans le present Memoire, on verra que Bans tout domaine pseudoconvexe sans point critique interieur ayant au moms un point f rontiere sur 1'espace projectif complexe a n dimensions, it existe une fonction pseudoconvexe ayant les proprietes d'Oka,2' qui est par definition meme, une fonction de Levi strictement positive et complete d'apres Nishino.
Arabicization or Englishization of higher education in the Arab world? Controversies, policies and realities

Though there have been many calls for the Arabicization versus Englishization of higher education in the Arab world, no previous work seems to have comprehensively covered these calls and their outcomes in the region. In this paper, the authors review literature on the following four main pertinent issues: (a) the arguments for and against the Arabicization versus Englishization of higher education in the Arab world; (b) Arabicization attempts of higher education; (c) current Englishization policies and orientations of Arab higher education systems; and (d) realities of EMI practices in Arab universities. It is concluded that higher education Arabicization movements in the Arab world have not brought about their desired outcomes due to some barriers, whereas Englishization policies and practices have increasingly expanded in the region in the last three decades. The paper ends with discussing the implications of the review.
Nonlinear fast magnetosonic waves in solar coronal holes

A coronal hole is modeled as a slab of cold plasma threaded by a vertical, uniform magnetic eld. A periodic driver acting at the coronal base is assumed to drive the velocity component normal to the equilibrium magnetic eld. Previous works indicate that, in the linear regime, only fast mode perturbations propagate, since Alfv en waves are excluded from the model and the slow wave is absent in the cold plasma limit. However, in this work, it is shown that nonlinear terms in the magnetohydrodynamic (MHD) equations give rise to excitation of the velocity component parallel to the equilibrium , with a lower amplitude than the normal component. Another consequence of nonlinearities is the generation of higher-frequency Fourier modes, which can be detected by Fourier analyzing the velocity variations above the photosphere. The nature of the nonlinear interactions in the MHD equations determines the frequency of those modes. These interactions are quadratic in the case of the parallel component, while they are cubic in the case of the normal component. Therefore, nonlinearly excited frequencies 2! d ,4 ! d ,6 ! d, ::: are present in the parallel velocity, whereas frequencies 3! d ,5 ! d ,7 ! d, ::: are present in the normal velocity, with ! d the driving frequency.
Econometric analysis of realized volatility and its use in estimating stochastic volatility models

Summary. The availability of intraday data on the prices of speculative assets means that we can use quadratic variation‐like measures of activity in financial markets, called realized volatility, to study the stochastic properties of returns. Here, under the assumption of a rather general stochastic volatility model, we derive the moments and the asymptotic distribution of the realized volatility error—the difference between realized volatility and the discretized integrated volatility (which we call actual volatility). These properties can be used to allow us to estimate the parameters of stochastic volatility models without recourse to the use of simulation‐intensive methods.