Miracle-dz/UniFAR-FTUs huggingface dataset:
Liming Positively Modulates Microbial Community Composition and Function of Sugarcane Fields

Liming combined with an optimum quantity of inorganic fertilizer, as a soil amendment in intensive agriculture, is a viable agricultural practice in terms of improving soil nutrient status and productivity, as well as mitigating soil degradation. The chief benefits of this strategy are fundamentally dependent on soil microbial function. However, we have limited knowledge about lime’s effects on soil microbiomes and their functions, nor on its comprehensive influence on soil nutrient status and the productivity of sugarcane plantations. This study compares the impacts of lime application (1-year lime (L1), 2-year lime (L2), and no lime (CK) on microbial communities, their functions, soil nutrient status, and crop yield in a sugarcane cropping system. We employed Illumina sequencing and functional analysis (PICRUSt and FUNGuild) to decipher microbial communities and functions. In comparison with CK, lime application (L1 and L2) mitigated soil acidity, increased the level of base cations (Ca2+ and Mg2+), and improved soil nutrient status (especially through N and P) as well as soil microbial functions associated with nutrient cycling and that are beneficial to plants, thereby improving plant agronomic parameters and yield. Liming (L1 and L2) increased species richness and stimulated an abundance of Acidobacteria and Chloroflexi compared to CK. In comparison with CK, the two functional categories related to metabolism (amino acid and carbohydrate) increased in the L1 field, whereas cofactors and vitamin metabolites increased in the L2 field. Turning to fungi, compared to CK, liming enriched symbiotrophs (endophytes, ectomycorrhizae, and arbuscular mycorrhizae) and led to a reduction of saprotrophs (Zygomycota and wood saprotrophs) and pathotrophs. The observed benefits of liming were, in turn, ultimately reflected in improved sugarcane agronomic performance, such as increased stalk height and weight in the sugarcane planting system. However, the increase in the above-mentioned parameters was more prominent in the L2 field compared to the L1 field, suggesting consecutive liming could be a practical approach in terms of sustainable production of sugarcane.
Luhong Granules Prevent Ventricular Remodelling after Myocardial Infarction by Reducing the Metabolites TMAO and LPS of the Intestinal Flora

Background Ventricular remodelling is a common pathological change at all stages of heart disease. Luhong granules are widely used in patients with chronic ventricular remodelling after myocardial infarction and can alleviate chest tightness, shortness of breath, and other symptoms. However, its effect on ventricular remodelling remains to be studied. Purpose In this study, we investigated the effects of these granules on myocardial fibrosis in a rat model of myocardial infarction in vivo. Methods Male Wistar rats were randomly divided into four groups: the sham operation group, the acute myocardial infarction (AMI) group, the Luhong granule group, and the vancomycin group, with a sample size (n) of 10 rats in each group. The AMI model was established in all rats by ligation of the left anterior descending (LAD) coronary artery (the sham operation group did not undergo ligation). Luhong granules (0.5 ml·kg−1·d−1), vancomycin (0.075 g·ml−1·d−1), and 0.9% saline (5 ml·kg−1·d−1 for the sham operation and AMI groups) were administered orally for 6 weeks. Echocardiography was used to check cardiac structure and function. Myocardial and small intestinal tissue morphology was observed by haematoxylin and eosin (H&E) staining, and heart samples were stained with Masson's trichrome to analyse myocardial fibrosis. 16S rDNA sequencing was performed to detect changes in the gut flora. The level of trimethylamine N-oxide (TMAO) in plasma samples was quantified by stable isotope dilution liquid chromatography-tandem mass spectrometry (LC-MS). Results H&E and Masson's trichrome staining of cardiac tissues showed that Luhong granules could partially reverse ventricular remodelling and improve intestinal barrier function (P < 0.05). Echocardiographic analysis showed that, compared with the AMI group, the left ventricular ejection fraction (LVEF) in the Luhong granule group was increased (P < 0.05). Stool sequencing and microbiological analysis showed changes in Bacteroidales, Alistipes, Phascolarctobacterium, etc., which can produce TMAO. We found that Luhong granules can reduce Bacteroidales, Alistipes, and Phascolarctobacterium at the genus level. The levels of TMAO and lipopolysaccharides (LPS) in plasma samples were reduced in the Luhong granule group (P < 0.05). Conclusions Our results indicate that Luhong granules reduce TMAO and LPS levels in circulating blood by improving intestinal flora and intestinal barrier function to delay ventricular remodelling after myocardial infarction.
ČASOPIS PRO PĚSTOVÁNÍ MATEMATIKY A FYSIKY

after attaining flae temperatures o f liquid helium was the superc o nductivity o f s o me metals. Alth o ugh a vast am o unt o f experimental facts has been c o llected since that time (1911) the difficulties in the interpretati o n o f these facts in terms o f the the o ries o f electr o nic c o nducti o n in metals seem still t o be insurm o untable. In this article a brief survey is given b o th o f the experimental as well as the the o retical aspects o f the pr o blem.
Sexual activity of women in different trimesters of pregnancy

Introduction. Sexual activity in pregnant women is often taboo. It is important to maintain intimate contacts, deepening ties with a partner. Pregnancy is a time of numerous changes in the female body, and the specific changes occur in the various trimesters of pregnancy with the development of the child. Plays an important role as a partner approach to pregnancy and its interest in the personal problems of a pregnant woman, because the mutual understanding between partners means that pregnancy is an incentive for them to seek new ways of sexual satisfaction. Aim: Characterization of form and frequency of sexual activity of women in different trimesters of pregnancy. Material and methods. The study was conducted in the years 2010 2011 and it included 200 women residing in the obstetric ward newborn in the Provincial Specialist Hospital of University in Lublin. Diagnostic survey method was used, the survey technique, the instrument was a questionnaire survey of his own design. The collected data were statistically analyzed. Before testing, the project received a positive opinion of the Bioethics Committee at the Medical University of Lublin. Results. The most common form of sexual activity in pregnant women were kissing, vaginal, petting and foreplay. Most women in different trimesters of pregnancy was sexually active once a week, while experiencing the feelings of pleasure. In most cases, pregnant women were not at risk, and sexual activity during pregnancy has decreased over time compared to pre-pregnancy. Conclusion. Sexual activity of women in different trimesters of pregnancy remains an embarrassing subject for women. Despite the absence of contraindications to sexual activity during pregnancy, women abandoned their many forms of sexual activity. Women were most active sexually in the first trimester of pregnancy, and are reluctant to enjoy the sexual satisfaction in the third trimester.
The development of legume-based yogurt by using water kefir as starter culture

The aim of the present work was to develop legume-based kefir yogurts to replace conventional dairy yogurts that are not suitable to be consumed by vegetarians and consumers who have lactose intolerance and milk allergy. Soy and black bean milk were incubated at 15°C and 20°C for 24 h with 35 g of water kefir grains to produce kefir yogurt. The proximate composition, physico-chemical and microbiological characteristics of the yogurts were evaluated. At 20°C, soy and black bean milk produced kefir yogurts with significantly lower pH, total soluble solids, and sucrose concentration, indicating that fermentation process carried out at 20°C had higher efficiency than 15°C; meanwhile, black bean milk produced better kefir yogurts than soymilk. Black bean kefir yogurt which was fermented at 20°C had higher level of total plate count (2.05 × 107 CFU/mL), yeast and mould count (6.95 × 106 CFU/mL), and lactobacilli count (8.3 × 105 CFU/mL) as compared to other kefir yogurts. In general, 20°C produced kefir yogurt with better technological properties. Both soymilk and black bean milk were good alternative substrates for kefir yogurt production.
University of Groningen Role of FDG PET/CT in monitoring treatment response in patients with invasive fungal infections Ankrah,

Introduction Invasive fungal infections (IFIs) occur mostly in immunosuppressed patients and can be life-threatening. Inadequate treatment is associated with high morbidity and mortality. We examined the role of 2-fluorodeoxyglucose positron emission tomography integrated with CT (FDG-PET/CT) in monitoring IFIs and therapy decision-making, and evaluated the role of baseline metabolic parameters in predicting the metabolic response. Methods All patients between October 2009 and March 2018, diagnosed with IFIs, treated with antifungal drugs, and who underwent FDG-PET/CT at baseline and at one or more timepoints during treatment were retrospectively included. The electronic patient files were reviewed for pathology, microbiology, and laboratory findings. All FDG-PET/CT scans were performed according to standardized European Association of Nuclear Medicine/EANM Research Limited (EANM/EARL) protocols. For each scan, the global total lesion glycolysis (TLG) and metabolic volume (MV), highest maximum standardized uptake value (SUVmax), and peak standardized uptake value (SUVpeak) were determined. The role of FDG-PET/CT on monitoring antifungal therapy was assessed by looking at the clinical decision made as result of the scan. Furthermore, the added value of the baseline metabolic parameters in predicting metabolic response to the antifungal treatment was evaluated. Results Twenty-eight patients with in total 98 FDG-PET/CT scans were included with a mean age of 43 ± 22 years. FDG-PET/ CT altered management in 14 out of the 28 patients (50%). At the final FDG-PET/CT scan, 19 (68%) had a complete metabolic response (CMR), seven a partial response and two patients were defined as having progressive disease. Using receiver operative analysis, the cut-off value, sensitivity, specificity, and significance for the baseline TLG and MV to discriminate patients with CMR were 160, 94%, 100%, p < 0.001 and 60, 84%, 75%, p = 0.001 respectively. Conclusion FDG-PET/CT is useful in the monitoring of IFIs resulting in management therapy change in half of the patients. Baseline TLG and MV were found to be able to predict the metabolic response to antifungal treatment.
Antioxidant, DNA protective and antibacterial activities of Terminalia bellerica extracts

Terminalia bellerica Roxb. , commonly known as Beleric myrobalan, is a well-known large deciduous tree with various pharmaceutical properties. However, scientific information on T. bellerica, growing in India, as regards to its phytochemical constituents and pharmacological properties is very limited. With this in view, this study investigated the antioxidant, DNA protective and antibacterial activities of different parts (fruit pulp, seed and bark) of T. bellerica. Methanol (70%) and water (100% distilled water) were used for the extraction and analysis of total phenolic contents (TPC). Plant extracts were further screened for antibacterial activity against both gram (+) and gram (-) bacteria and minimum inhibitory concentration (MIC) values were calculated. Amongst the tested extracts, methanolic extract contained more TPC than aqueous extract. Methanolic fruit pulp (MEFP) showed lower IC50 (118.7 µg/ml) for free radical, (77.65 µg/ml) superoxide anion radical, (73.76 µg/ml) hydroxyl radical scavenging activity, (115.6 µg/ml) lipid peroxidation and (184.98 µg/ml) ferric thiocyanate assay. Methanolic extract also exhibited more potential DNA protective and antibacterial activity than aqueous extract. Furthermore, the correlation between TPC and antioxidant studies revealed that phenolics are mainly responsible for antioxidant, DNA protective and antibacterial activities of T. bellerica. This study suggests that the methanolic extract of T. bellerica could be a potential source of natural antioxidants. Key words: Terminalia bellerica, antioxidative, DNA protective, antibacterial.
DMSO_A_211776 2395..2404

*These authors contributed equally to this work Background: The metabolic syndrome (MetS) is highly prevalent and associated with higher risk of diabetes and cardiovascular events. Exercise programs have been shown to improve components of MetS, but the optimal design of a structured exercise program for treatment of the MetS remains unclear. Purpose: To assess the impact of different exercise programs on the MetS and its components. Methods: MEDLINE via PubMed and Embase was searched. Randomized controlled trials of supervised exercise alone and in combination with nutrition programs compared with usual care in adults with the MetS were selected. Two authors independently reviewed articles to select eligible studies and performed data abstraction. Eight studies representing 1218 patients were included. The participants had a median age of 51, median BMI of 29 kg/m, and were 55% male. Mean weight loss increased with program duration. For combination programs, the mean weight loss was −2.6 kg, −3.7 kg, and −6.5 kg for 3, 6, and 12 months, respectively. The components of the MetS most frequently statistically significantly improved were waist circumference (6/6 studies), blood pressure (4/6 studies), and high-density lipoprotein cholesterol (3/6 studies). Limitations: Studies did not include long-term follow-up post program completion to evaluate persistence of benefit. It is unknown whether the same results would be found in an older, more obese population. Conclusion: Supervised exercise programs yield significant resolution of components of the MetS, particularly in reducing waist circumference. Longer program duration and frequent interval sessions appear to have highest benefit and thus may help reduce cardiovascular risk and diabetes associated with the MetS.
“What’s the verdict?”: Measuring differences in students’ attitudes towards Autism Spectrum Disorder (ASD) and non-ASD sex offenders.

The previous research has neglected to measure attitudes towards ASD sex offenders. The current study used a 20-item, 5-point Likert scale questionnaire, created by the researcher, to measure and compare the differences in attitudes of undergraduate students towards ASD and non-ASD sex offenders. The two participant groups were provided with separate vignettes to read regarding a fictional sex offender; and they then completed the three-section questionnaire.Independent Sample T-Tests in SPSS software was used to calculate the mean and significance of the participants’ scores between the ASD and the control group. Results showed a significant difference in scores between the ASD and control group for section 1, which was directly pertinent to the vignettes, but no significant differences were found in sections 2, 3 or in the total questionnaire scores. This research discusses the implications of leniency towards ASD sex offenders in government legislation and in jury-settings.
Intellectual capital and market value: evidence from Jordan

This research aims to apply the value-added intellectual coefficient (VAIC) model to test the impact of intellectual capital (IC) on market value of the Jordanian industrial firms. The research increases the awareness of the need for firms of all sizes to communicate and value their business beyond capturing numbers alone. The sample for this study is 73 Jordanian manufacturing shareholders companies during the period 2005–2017. The sample employed consists of 648 firm-year observations. Market value is measured using the market capitalization over the total assets. Valuation approaches are a challenging area created to enable the stakeholders, or outside parties, to put an economic value on a firm.The IC and its components: capital employed (CEE), structural capital (SCE), and human capital (HCE) of industrial firms have been analyzed, and their impact on market value has been estimated using regression models. The results show that there is no relationship between IC and the market value; HCE is associated with the market value, and SCE and CEE are not associated with the market value. This could be explained by the increase in employees’ training, as a regular training program is an essential factor in managers’ and employees’ performance. Practically, investors have a positive view of a firm that has higher employee expenditure than its investment in physical capital. Future research should be made on the empirical analysis of other sectors to determine whether different results and explanations can be obtained.
Cerebroventricular Injection of Cigarette Smoke Condensate Produce Generalized Seizures Decreased by Muscarinic Receptor Antagonist in Rats

Tobacco smoke is a complex multicomponent system, in which more than 4800 compounds have been identified by chromatographic techniques; many of these compounds are carcinogenic. However, there is a great deal of research into the association between smoking and diseases such as heart attacks, strokes and cancers. Nevertheless rare are the studies on the association between smoking and epilepsy because the exact roles of smoking and nicotine use in epilepsy have not been well examined. In this study the authors evaluate the convulsive effects of intracerebroventricular administration of cigarette smoke condensate in rats and compare intensity of seizures with kainic acid-induced seizures as a model of epilepsy. The role of cholinergic system was also evaluated using mAChRs antagonist in cigarette smoke condensate (CSC) induced seizures. Results indicate that central injection of cigarette condensate provides an epileptic behavior similar to that induced by kainic acid. However a pretreatment with atropine reduced seizures and all their parameters.
Management of false smut disease of rice

The study was conducted in Palamu district of Jharkhand to know the socio-economic status of farmers. They were categorized in three groups i.e. small, medium and large farmers which were differ from each other with regard to socio–economic factors and found that 54.66 per cent rice growers has medium level of knowledge. Most of the small category farmers have high technological gap of lack of technological guidance (69.60%) followed by lack of money (66.13 %). The different sub practices grouped into 6 categories and found that plant protection measures is one of the major concerns for technological gap First spray of Carbendazim 50 WP @ 2 g/l of water before panicle initiation and second at milking stage Propiconazole 25EC @ 1 mi/l of water was effective in reducing incidence of false smut diseases and increased the grain yields.
African Journal of Pharmacy and Pharmacology Vol

To explore the effect of Xingnaojing on the somatostain and arginine vasopressin in a rat vascular dementia model, a total of 24 male Sprague-Dawley rats were randomly divided into three groups: sham group (S), vascular dementia group (VD) and Xingnaojing group (XNJ). The memory was measured by Morris water maze test before operation and before and after Xingnaojing treatment. Treatment was performed for 15 days, and then rats were sacrificed. The contents of somatostain (SS) and arginine vasopressin (AVP) in different brain regions (frontal cortex, temporal lobe, hippocampus, cerebral ganglion and corpora striatum) were determined by radioimmunoassay. When compared with S and XNJ groups, the escape latency was significantly prolonged and the platform crossing dramatically decreased in the VD group (P < 0.01); and the SS content was predominantly decreased in frontal area cortex, temporal lobe, hippocampus, cerebral ganglion and corpora striatum (P < 0.01). The AVP content was reduced, but significant difference was only found in the temporal lobe and corpora striatum (P < 0.05). The abnormal learning and memory in VD animals may be attributed to the decrease of SS and AVP after multiple cerebral infractions. Xingnaojing can predominantly raise the contents of SS and AVP in the brain of VD rats, and consequently improve the spontaneous activity and the ability of learning and memory. Xingnaojing injection should be sealed from light, in ampoule bottles, 10 ml each, and this product is an aromatic drug, used immediately after opening, to prevent evaporation.
Nurses’ attitudes and behaviors during bachelor of nursing students’ clinical learning experiences

Objective: This study aimed to examine the nurse-student relationship during clinical learning experiences.Methods: Students at all levels of a Bachelors nursing program completed the Nursing Student Perception of Civil and Uncivil Behaviors tool (NSPCUB) after clinical experiences during each semester over one calendar year at a small Midwestern university. The tool included 12 items, four demographic questions, and two qualitative questions.Results: A total of 302 surveys were returned. The majority of surveys were completed by second semester students on a medical-surgical unit. The majority of students had positive experiences. Night shift nurses had a significantly higher mean on two variables. There was also statistical significance between second and third semester students on two variables. There were no statistical differences between units and hospitals. Student’s comments were mostly positive, though negative experiences still occurred.Conclusions: Nurses can positively impact student’s clinical learning experiences. Students have both positive and negative experiences in the clinical setting. Several positive themes were identified including role modeling, skill acquisition/teaching, communication and critical thinking development. Negative themes also occurred including rudeness, feeling ignored and inappropriate behavior. Further research is recommended.
Evaluation of aphrodisiac properties of the aqueous extract of the trunk barks of Spathodea campanulata P. Beauv. (Bignoniaceae) on albino rats (Rattus norvegicus)

Spathodea campanulata P. Beauvois (Bignoniaceae) is a tree from the tropical and subtropical forests of Africa, used in folk medicine for the treatment of several diseases such as gastric pain, rheumatism, lumbago, cataracts and some intestinal parasites. In West Cameroon, traditional healers use a decoction of the bark of the trunk as an aphrodisiac in males. The objective of the present study was to evaluate the aphrodisiac activity of the aqueous extract of the trunk barks of S. campanulata in male rats. The male rats were divided into five lots: A, B, C, D and E of six animals each. Lot A received 5 ml/kg of distilled water daily for 8 days (negative control). Lot B received 5 mg/kg of Sildenafil Citrate (Viagra®) daily for 8 days (positive control). Lots C, D and E received 200, 400 and 800 mg/kg, respectively of the aqueous extract of the trunk barks of S. campanulata daily for 8 days. On the first, fourth and eighth day of administration, the copulatory parameters were observed and recorded. The extract induced an increase in erectile function stimulation through the significant increase (p<0.001) in the number of erections, the frequency of mount and a decrease in mount latency, reflecting an increase in sexual stimulation; an increase in the frequency of intromission (p<0.001) and a decrease in intromission latency, reflecting a stimulation of sexual performance. There was also an increase in ejaculation frequency and ejaculation latency (p<0.001). These results indicate a pro-ejaculatory aphrodisiac potential of the aqueous extract of the trunk barks of S. campanulata in male rats and would justify the empirical use of this plant in the treatment of erectile dysfunction in humans, in traditional medicine. Key words: Spathodea campanulata, aqueous extract, erectile dysfunction, aphrodisiac, male rat.