Miracle-dz/UniFAR-FTUs huggingface dataset:
Development of a Biodegradable Electro-Insulating Liquid and Its Subsequent Modification by Nanoparticles

The paper is focused on the possibility of replacing petroleum-based oils used as electro-insulating fluids in high voltage machinery. Based on ten years of study the candidate base oil for the central European region is rapeseed (Brassica napus) oil. Numerous studies on the elementary properties of pure natural esters have been published. An advantage of natural ester use is its easy biodegradability, tested according to OECD–301D (Organisation for Economic Co-operation and Development) standard, and compliance with sustainable development visions. A rapeseed oil base has been chosen for its better resistance to degradation in electric fields and its higher oxidation stability. The overall ester properties are not fully competitive with petroleum-based oils and therefore have to be improved. Percolation treatment and oxidation inhibition by a phenolic-type inhibitor is proposed and the resulting final properties are discussed. These resulting fluid properties are further improved using titanium dioxide (TiO2) nanoparticles with a silica surface treatment. This fluid has properties suitable for use in sealed distribution transformers with the advantage of a lower price in comparison with other currently used biodegradable fluids.
Mathematially based management of Saccharomyces sp. batch propagations and fermentations

Yeast propagation increasingly stands for a central step in beer production and emprises an important economical and technological factor in brewing practice. Vitality and quality of the propagated yeast exerts a relevant influence on the subsequent fermentation run and the resulting beer quality. Therefore, the yeast inoculum must be available at pitching time in the right amount and especially in the right quality. To guarantee this by process management tools, in particular by modelling and active process control, is a main feature of this work. Two kinetic models of yeast propagation are introduced. These modelling approaches represent the basis for a control strategy aiming on the provision of an optimal inoculum at the starting time of subsequent industrial fermentations. Both models, a Black Box model and a metabolic model, include respiratory metabolism on sugars and ethanol as well as fermentative metabolism on sugars. Limitation effects, occurring due to specific nutritional data of the growth medium beer wort, were taken into account for sugar, nitrogen, ethanol and oxygen concentrations. Correspondingly, inhibitions of the metabolism by ethanol and high sugar concentrations were formulated. The models especially represent the Crabtree-effect. For model validation, literature data were used and selected experiments within the relevant range of manipulated variables (temperature, dissolved oxygen) were conducted for different yeast strains and propagation strategies. In a sensitivity analysis three parameters were identified as particularly relevant. After adaptation of these parameters on data sets, simulations, based on the suggested models, matched these data with a deviation below 10 mmol/L (0.2% w/w for sugar concentrations and 6.2*106 cells/mL for biomass concentration). The variable parameters showed a characteristic temperature dependency, which could be described by mathematical functions. The implementation of these functions in both models allowed predictive simulations of the yeast propagation process even applying non-isothermal trajectories. During experiments it was proved that in ideally mixed fermenters the dissolved oxygen concentration affects the yeast growth only below concentrations of 0.1 ppm. Predictive simulations allowed an active process control by a precise adjustment of trajectories of both, temperature and dissolved oxygen concentration. Thus, the optimal crop time of the inoculum could be varied within a period of two days in order to maintain high fermentation activity for the subsequent anaerobic fermentation. The validity of the modelling approaches was proved for industrial propagations and fermentations in breweries as well. In particular for the industrial propagations above mentioned accuracies were achieved. Accuracies of the simulation of brewing yeast fermentations resulted in a practicable range not before a sedimentation model was included in the process models.
Practice patterns for Lynch syndrome-associated endometrial cancer management in Korea

Objectives: This study aimed to investigate practice patterns for the management of LS-associated endometrial cancer among Korean gynecologic oncologists. Material and methods: Members of the Korean Society of Gynecologic Oncology were surveyed using a selfadministered questionnaire regarding their knowledge and clinical management of LS by paper or e-mail. Results: Of the 49 participants, the median age was 43 years (range, 30–75). The respondents worked mainly in Seoul (25/49, 51.0%) and the capital area (16/49, 32.7%). The average score on LS knowledge assessment was 3.8 (range, 0–8) with a maximum score of 8. The following tools were used by the respondents for the identification of inherited endometrial cancer: obtaining of family history (46.7%), immunohistochemistry (IHC) test for four mismatch repair (MMR) genes (38.8%), and microsatellite instability (MSI) test (8.2%) for all endometrial cancer patients. The indications for recommending the germline MMR gene test were endometrial cancer with a family history (5/49, 10.2%), patients who met the Amsterdam II criteria (32/49, 65.3%), abnormal IHC test results (13/49, 26.5%), and abnormal MSI test results (8/49, 16.3%). Approximately half of the respondents recommended cascade testing (28/49, 57.1%) to the family of the proband and recommended riskreducing management for MMR mutation carriers (27/49, 55.1%). Conclusion: Gynecologic oncologists in Korea are not aware of genetic risk assessment and patient counseling about LS. Therefore, it is necessary to educate physicians and develop guidelines in this regard.
The Technical Default Spread

We build a dynamic general equilibrium model in which endogenous loan covenants allocate investment control rights between borrowers and lenders, and study its implications for investment, risk-taking, and asset prices in the cross-section. When borrowers enter technical default by breaching a covenant, control rights switch from borrowers to lenders. Lenders optimally choose low-risk projects, thus mitigating borrowers’ risk-shifting incentives and reducing the firm’s cost of equity. A calibrated version of our model allows us to match the technical default spread that we find in the data: firms that are closer to technical default earn on average 4% lower future returns than firms that are further away from their technical default thresholds. We argue theoretically and show empirically that the technical default spread arises from different economic forces than the distress anomaly. JEL Codes: E2, E3, G12
A Probable Mechanism for Recurring Outbreak of Respiratory Syndrome During Autumn Season in Ahvaz City, Iran

Background: Recurring annual asthma or asthma-like outbreak in Ahvaz City, Iran, has become a serious public health problem. A toxic gas, a chemical compound, or an allergen with unknown nature and mechanism leads to severe asthma outbreaks each year. Bronchospasm, cough, dyspnea, chest tightness, and wheezing are the main symptoms of these attacks. Oxygen and anti-asthma therapy are effective treatments in outbreak management. Based on our findings, it is hypothesized that vast amounts of ammonium nitrate used in agriculture underlay high concentrations of nitrate. This substance is transported by PM10 and is the main cause of the respiratory outbreak. Methods: The concentration of nitrate was determined by the ion chromatography method in dust samples during 2015-2016. Using spectroscopic methods, the effect of nitrate ions on hemoglobin oxidation and methemoglobin formation was studied. Results: Our results indicate that the concentration of ammonium nitrate in dust collected from indoor spaces is five times higher than the levels allowed amount in airborne pollutants. Our findings also indicate that this concentration of nitrate in the bloodstream can instantly increase methemoglobin percent to 18% with symptomatic consequences. Conclusion: The exact mechanism proposed by this study is that inhaled nitrate or nitric acid finally increases the nitrate in the circulation of affected individuals. Hemoglobin oxidation and methemoglobin formation are the subsequent events leading to methemoglobinemia with asthma-like reactions seen in Ahvaz respiratory syndrome. Restricting or even prohibiting ammonium nitrate application in agriculture seems to be an urgent measure to stop Ahvaz's recurring respiratory syndrome.
Impacts of Catfish Effluents on Water Quality Parameters of Majidun Stream, South-West, Nigeria

There has been a great concern about the level of safety of surface waters, especially in developing countries where there is an exponential increase in water pollution and water-borne diseases. The aim of this study was to assess the effect of catfish pond effluents on water quality of stream water where five catfish farms were located. Water samples were taken on monthly basis, 20 cm of below water surface from the streams that receive effluents from neighboring fishponds. Water quality indicators like dissolved oxygen, biochemical oxygen demand (BOD5), nitrate, nitrite, water temperature, ammonia and Hydrogen ion Concentration (pH) were examined in the sampled waters in accordance with the American Public Health Association standards. The average values of water quality indicators examined at effluents and non-effluents discharged sites of the stream indicated that water (24.6 ± 0.2, 24.2 ±0.1), (7.29±0.30, 7.30±0.10), (6.90±0.4, 7.07±0.1 mg/l), (0.40±0.04, 0.27±0.01), (3.77±0.26, 2.34±0.16 mg/l), (3.59±0.11, 2.80±0.02 mg/l) and (3.51±0.24, 2.46±0.21 mg/l) at (p≥0.05) respectively for temperature, pH, dissolved oxygen, total ammonia, total nitrogen, total phosphorus, and BODs. They were significant differences (P 0.05) excepts temperature and pH, between values obtained at effluents discharged and non-effluents discharged sites, indicating that improper discharges of catfish pond effluents could resulted into environmental contamination
Caesarean sections and outcomes of labor induction after the introduction of a new intravaginal device: retrospective analysis

Background: To evaluate the outcomes and process of labour induction following the introduction of a new vaginal device with slow releasing dinoprostone (Propess). Methods: Data were collected on the indications for labour induction, the process of induction and delivery, and the outcomes of delivery for 171 term pregnancies between 1 January 2020 and 31 August 2020. Excluded from this study were patients with preterm delivery, multiple pregnancies, or pre-labour rupture ofmembranes. Data for the standard dinoprostonemedication (PG)andPropessgroupswasanalysedandcompared. Results: Of the 93women (54.4%of total) induced in thePGgroup, 55 (59.1%) received Prostin tablets, 17 (18.3%) received 1 mg of Prostin gel, and 21 (22.6%) received 2 mg of Prostin gel. Seventy eight women (45.6%) received the new intravaginal device (Propess group). The five most frequent indications for labour induction were post-term pregnancy (53, 31.0%), GDM (42, 24.6%), oligohydramnios (30, 17.5%), IUGR (21, 12.3%), and hypertensive disease (20, 11.7%). The Bishop scores were unfavourable in the majority of cases (119, 69.6%). The length of induction was less than 24 hours in 134 women (78.4%). Oxytocin was usedmore frequently (p = 0.001) in the Propess group and thesewomenunderwentmore frequent caesarean section (20.5%vs 12.9%, p=0.31). The statusofbabieswasgood inbothgroups. Conclusion: Introduction of the Propess device tomainstreammedical practice has led to rapid implementation and resulted in improvedworklow and positive outcomes for both the baby andmother.
Analysing the satisfaction of halal restaurant guests through online ratings on TripAdvisor

Providing halal products is one of the key factors in the lives of members of the Islamic faith. The physical and economic availability of halal food has an important place in the decision-making process about the movements of Muslim tourists. Currently, the Halal market is rapidly expanding, contributing to an increase in the number of the Muslim population and their travels. The main goal is to analyse the satisfaction of halal restaurant guests expressed through online numerical ratings. Authors used automated techniques for collecting guests’ ratings. Restaurants that were analysed were chosen by selecting the criteria “halal” on TripAdvisor. Information about the origin of reviewers and gender are also collected. The paper also tries to answer the question whether the origin of guests and type of halal restaurants have an influence on their satisfaction with services in selected facilities. The results indicated the presence of significant differences in guest’s satisfaction among different types of restaurants. One of the possible limitations of this research is an insufficient number of evaluating criteria for expressing a satisfaction which are available on TripAdvisor for analysis that is more precise.
CMAR_A_288522 181..192

*These authors contributed equally to this work Objective: To determine the independent and combined prognostic value of sarcopenia and systemic inflammatory markers in esophageal cancer patients undergoing definitive radiotherapy. Methods: Sarcopenia was diagnosed on the basis of the skeletal muscle index (SMI) as determined by the skeletal muscle area at the third lumbar (L3) region and body height. The optimal cutoff value of systemic inflammatory markers was determined by the receiveroperating curve (ROC). Logistic regression was used to analyze the correlation among different variables. Cox proportional hazards model was used to identify the factors significantly correlated to overall survival (OS). Based on the results of multivariate survival analysis, a nomogram was established to predict the survival rate. The accuracy of the nomogram was evaluated by the coordination index and the calibration curve. Results: A total of 100 esophageal cancer patients were included, of which 77 exhibited sarcopenia. The lymphocyte–monocyte ratio (LMR) was significantly correlated to the risk of sarcopenia (OR = 0.637, 95% CI, 0.452–0.898, P = 0.010). In addition, sarcopenia (P = 0.002, HR = 3.991, 95% CI: 1.653–9.638) and LMR < 2.67 (P < 0.001, HR = 2.665, 95% CI: 1.563–4.543) were independent predictors of OS. Two nomograms with good predictive accuracy were established. Conclusion: Sarcopenia and LMR can independently predict the survival of patients with esophageal cancer receiving definitive radiotherapy and have good combined prognostic value.
The Impact of e-Learning Quality on Student Satisfaction and Continuance Usage Intentions during COVID-19

—The COVID-19 pandemic has severely affected people’s lives, changing the ways of working, living, playing, and learning. With this pandemic, classroom learning has been suspended due to infection concerns, and e-learning has emerged, becoming an important mechanism for educational institutions to continue their teaching and learning activities. However, there have been only a few empirical studies providing insight into the factors affecting students’ e-learning satisfaction and usage behaviors during the COVID-19 outbreak. Thus, this study aims to investigate the impact of e-learning quality on student satisfaction and continuance usage intentions among higher education students in Thailand during the pandemic. Based on empirical research with 185 higher education students, the results revealed that e-learning quality was a second-order construct comprised of three elements, namely, course content and design, administrative and technical support, and instructor and learner characteristics. Course content and design was the most important dimension of overall e-learning quality. Furthermore, overall e-learning quality had a significant positive impact on student satisfaction and continuance usage intentions toward e-learning platforms. Mediation analysis indicated that student satisfaction partly mediated the relationship between e-learning quality and continuance usage intentions. © 2021, International Journal of Information and Education Technology. All rights reserved.
In vitro Antioxidant, Cytotoxic and Antidiabetic Activities of Protein Hydrolysates Prepared from Chinese Pond Turtle (Chinemys reevesii)

SUMMARY Research background Cardiovascular diseases and diabetes are the biggest causes of death globally. Bioactive peptides derived from many food proteins using enzymatic proteolysis and food processing have a positive impact on the prevention of these diseases. The bioactivity of Chinese pond turtle muscle proteins and their enzymatic hydrolysates has not received much attention, thus this study aims to investigate their antioxidant, antidiabetic and cytotoxic activities. Experimental approach Chinese pond turtle muscles were hydrolysed using four proteolytic enzymes (Alcalase, Flavourzyme, trypsin and bromelain) and the degrees of hydrolysis were measured. High-performance liquid chromatography (HPLC) was conducted to explore the amino acid profiles and molecular mass distribution of the hydrolysates. The antioxidant activities were evaluated using various in vitro tests, including 1,1-diphenyl-2-picrylhydrazyl (DPPH) and 2,2’-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS), hydroxyl radical scavenging activity, reducing capacity, chelating Fe2+ and lipid peroxide inhibition activity. Antidiabetic activity was evaluated using α-amylase inhibition and α-glucosidase inhibition assays. Besides, cytotoxic effect of hydrolysates on human colon cancer (HT-29) cells was assessed. Results and conclusions The amino acid composition of the hydrolysates revealed higher mass fractions of glutamic, aspartic, lysine, hydroxyproline and hydrophobic amino acids. Significantly highest inhibition of lipid peroxidation was achieved when hydrolysate obtained with Alcalase was used. Protein hydrolysate produced with Flavourzyme had the highest radical scavenging activity measured by DPPH (68.32%), ABTS (74.12%) and FRAP (A700 nm=0.300) assays, α-glucosidase (61.80%) inhibition and cytotoxic effect (82.26%) on HT-29 cell line at 550 µg/mL. Hydrolysates obtained with trypsin and bromelain had significantly highest (p<0.05) hydroxyl radical scavenging (92.70%) and Fe2+ metal chelating (63.29%) activities, respectively. The highest α-amylase (76.89%) inhibition was recorded when using hydrolysates obtained with bromelain and Flavourzyme. Novelty and scientific contribution Enzymatic hydrolysates of Chinese pond turtle muscle protein had high antioxidant, cytotoxic and antidiabetic activities. The findings of this study indicated that the bioactive hydrolysates or peptides from Chinese pond turtle muscle protein can be potential ingredients in pharmaceuticals and functional food formulations.
PHYTOCHEMICAL SCREENING AND ANTIOXIDANT ACTIVITY OF BANANA PEEL

Banana (Musa paradaisica), is grown worldwide and consumed as ripe fruit or used for culinary purposes. Peels form about 18-33% of the whole fruit and are a waste product. With a view to exploiting banana peel as a source of valuable components, the nutritional composition, antioxidant components were determined. The phytochemical analysis of aqueous and organic solvent extracts of banana peel (Musa Paradisiaca) reveal the presence of alkaloids, flavanoids, carbohydrates, proteins, Tannins, Terpenoid, Saponins, Glycosides and Anthroquiones. The phytochemicals alkaloids, flavanoids and tannins have a very good antioxidant property while saponins and terpenoids have antimicrobial activity. The qualitative analysis of Aqueous and organic solvent extracts of banana peel (Musa Paradisiaca) reveals the presence of reducing sugar (glucose and fructose). The qualitative analysis of Amino acids in banana peel (Musa Paradisiaca) reveals the presence of tryptophan, phenylanine, tyrosine, ariginine and cysteine. The quantitative analysis of starch, Proteins were done. The proteins and carbohydrates contents were higher in Musa paradisiaca peel extracts of ethanol. The qualitative analysis of tryptophan were carried out in Musa paradisiaca peel extract and the tryptophan was found to be higher in water and ethanol extracts. The amino acid typtophan is the precursor for the formation of serotonin which plays an important role as a neurotransmitter. In the central nervous system, serotonin plays an important role as a neurotransmitter in the modulation of anger, aggression, body temperature, mood, sleep, human sexuality, appetite, and metabolism. The qualitative analysis of minerals like Iron, Phosphorous, calcium, potassium, sodium were carried out in banana peel (Musa Paradisiaca). The mineral compound was higher in the aqueous extract then the organic extracts. Potassium ions plays an important role in the muscle construction and nerve impulse transmission. Sodium ions are necessary for the regulation of body fluids and blood. Phosphorous helps to maintain normal Acid-base balance by acting as one of the body’s most important buffer. Iron is necessary to deliver oxygen through the body in the form of hemoglobin.
DMSO_A_288065 367..377

1Clinical Trials Unit, The First Affiliated Hospital of Sun Yat-Sen University, Guangzhou 510080, People’s Republic of China; 2Department of Endocrinology, The First Affiliated Hospital of Sun YatSen University, Guangzhou 510080, People’s Republic of China; 3Phase I Clinical Trial Center, The First Affiliated Hospital of Sun Yat-Sen University, Guangzhou 510080, People’s Republic of China; 4Department of Medical Records, The First Affiliated Hospital of Sun YatSen University, Guangzhou 510080, People’s Republic of China
State-of-the-Art and Challenges of Vehicle Dynamics with Multibody Dynamics Approaches

A review of the current use of multibody dynamics methods in the analysis of the dynamics of vehicles is given. Railway vehicle dynamics as well as road vehicle dynamics are considered, where for the latter the dynamics of cars and trucks and the dynamics of single-track vehicles, in particular motorcycles and bicycles, are reviewed. Commonalities and differences are shown and open questions and challenges are given as directions for further research in this field.
Board structure and disclosure of intellectual capital: An empirical study in an emerging market

Capital market regulators have concentrated on company transparency, including and also intellectual capital disclosure (ICD) throughout the previous decade. Jensen and Meckling (1976) stated that high disclosure can reduce agency costs and the uncertainty faced by investors. This research aims to explore the ways the board structure, comprising board size, independence, female board members and CEO dichotomy, affects intellectual capital disclosure within Indonesia. A sample comprising 323 non-commercial companies in 7 industries listed publicly from 2008 to 2017 on Indonesia Stock Exchanges (IDX) was analyzed using ordinary least squares (OLS) regression. This study found a positive and signiﬁcant impact of board size which implied that a higher total number of members of the board of directors results in a higher extent of ICD. The larger the number of outside board members, the better. This makes the board more independent and allows it to provide a higher level of corporate governance to shareholders. The findings revealed the level of ICD significantly and negatively affected CEO duality statistically. The complete findings indicated robust implications of board structure for ICD. This study may be utilized to facilitate higher intellectual capital awareness and foster ICD execution by IDX capital market administrators.