Miracle-dz/UniFAR-FTUs huggingface dataset:
Seismic hydraulic fracture migration originated by successive deep magma pulses: The 2011–2013 seismic series associated to the volcanic activity of El Hierro Island

In this manuscript we present a new interpretation of the seismic series that accompanied eruptive activity off the coast of El Hierro, Canary Islands, during 2011–2013. We estimated temporal variations of the Gutenberg‐Richter b value throughout the period of analysis, and performed high‐precision relocations of the preeruptive and syneruptive seismicity using a realistic 3‐D velocity model. Our results suggest that eruptive activity and the accompanying seismicity were caused by repeated injections of magma from the mantle into the lower crust. These magma pulses occurred within a small and well‐defined volume resulting in the emplacement of fresh magma along the crust‐mantle boundary underneath El Hierro. We analyzed the distribution of earthquake hypocenters in time and space in order to assess seismic diffusivity in the lower crust. Our results suggest that very high earthquake rates underneath El Hierro represent the response of a stable lower crust to stress perturbations with pulsatory character, linked to the injection of magma from the mantle. Magma input from depth caused large stress perturbations to propagate into the lower crust generating energetic seismic swarms. The absence of any preferential alignment in the spatial pattern of seismicity reinforces our hypothesis that stress perturbation and related seismicity, had diffusive character. We conclude that the temporal and spatial evolution of seismicity was neither tracking the path of magma migration nor it defines the boundaries of magma storage volumes such as a midcrustal sill. Our conceptual model considers pulsatory magma injection from the upper mantle and its propagation along the Moho. We suggest, within this framework, that the spatial and temporal distributions of earthquake hypocenters reflect hydraulic fracturing processes associated with stress propagation due to magma movement.
The mediating role of social support in promoting physical activity among children in South Africa

Background Low physical activity (PA) participation levels and increasing non-communicable diseases in children are concerning in South Africa and globally. Objectives We sought to assess the mediating role of perceived social support factors on the relationship between PA enjoyment and PA levels among rural, peri-urban and urban school children. Method A cross-sectional study was adopted to assess peer, family and teacher encouragement as mediators on the relationship between perceived PA enjoyment and perceived physical activity participation among children, using the Physical Activity Questionnaire for Older Children (PAQ-C). The sample comprised a random sample of primary school learners aged 9–14 years. Results The sample consisted of 870 primary school learners with a mean age of 11.0 ± 1.49 years. Most participants were girls (n = 519; 59.7%). The findings suggest low levels of perceived PA participation (mean = 2.33, standard deviation [s.d.]: 0.43). Peer (β = 0.0187, 95% confidence interval [CI]: 0.0088, 0.0307), family (β = 0.0280, 95% CI: 0.0155, 0.0425) and teacher (β = 0.0242, 95% CI: 0.0127, 0.0378) encouragement partially mediates the relationship between perceived PA enjoyment and perceived PA participation. Family encouragement (β = 0.0158, 95% CI: 0.0017, 0.0311) has the most considerable mediating effect, followed by teacher encouragement (β = 0.0125, 95% CI: 0.0010, 0.0269). Conclusion The findings demonstrated low levels of perceived PA participation in school learners. Therefore, we recommends including social factors as mediators in PA intervention programmes in primary schools. Clinical implications Social support factors as mediators on the relationship between PA enjoyment and PA participation among children may improve children’s PA participation levels and help prevent non-communicable diseases in future.
LATEST CAMBRIAN CORNUTES (ECHINODERMATA: STYLOPHORA) FROM THE TAEBAEKSAN BASIN, KOREA

Abstract The oldest echinoderms and first cornute stylophorans ever reported from Korea are described, based on more than 40 specimens collected from the Late Cambrian of the Taebaeksan Basin. New material doubles the number of stylophorans described from Asia and the number of specimens of Late Cambrian stylophorans recorded throughout the world. Three different cornutes are identified: Sokkaejaecystis serrata n. gen. and sp. and two genus and species indeterminate forms A and B. Sokkaejaecystis serrata and indeterminate form B are assigned to the Chauvelicystinae, while the systematic position of indeterminate form A within cornutes is difficult to assess. This new material suggests paleobiogeographic connections between echinoderm faunas from Korea, western North America (Wyoming), and western Europe (Montagne Noire, Shropshire). A cladistic analysis of selected cothurnocystids shows that Sokkaejaecystis n. gen. is closely related to Prochauvelicystis and the sister group of a clade uniting Ampelocarpus with Lyricocarpus. The analysis also confirms the placement of Milonicystis within the Chauvelicystinae and questions the monophyly of the genus Chauvelicystis.
Eliminating Spatial Correlations of Anomaly: Corner-Visible Network for Unsupervised Hyperspectral Anomaly Detection

Hyperspectral anomaly detection (HAD) is crucial for identifying and analyzing abnormal objects in various domains. While existing methods have shown promising results by designing detection methods tailored to specific anomaly characteristics, there is a need for a highly versatile approach that can effectively handle anomalies, particularly those with large spatial sizes. In this article, we propose an end-to-end corner-visible network (CVNet) for unsupervised HAD. Specifically, we introduce a corner-visible convolution that leverages the statistical dependencies of the background within the receptive field while eliminating spatial correlations with potential anomalies for background generation. To address the grid effect caused by the corner-visible convolution, a background smoothing module is employed by using the conventional convolution. Furthermore, adaptive mean-squared error (MSE) and structural similarity index (SSIM) losses are employed to suppress anomaly reconstruction, resulting in a reliable reconstructed background map. Anomalies are identified through the residual of the original hyperspectral image (HSI) and the reconstructed background. Extensive experiments conducted on three publicly datasets demonstrate the effectiveness of our proposed method in handling different types of anomalies. The state-of-the-art performance showcases the versatility and applicability of CVNet in HAD. The codes of this work will be available for the sake of reproducibility at https://github.com/Cloudynewbee/CVNet-HAD.
Tomographic image of the axial low‐velocity zone at 12°50′N on the East Pacific Rise

The 1982 MAGMA seismic refraction experiment yielded a large set of accurate P wave travel times corrected for bathymetry and anisotropy which sample the structure of the East Pacific Rise (EPR) at 12°50′N. The arrivals were recorded using ocean bottom seismographs at three sites: on axis, and at 7 km and 16 km east of the axis. We invert 2320 travel times for the twodimensional crustal seismic velocity structure across the EPR axis, assuming that the velocity structure is invariant along strike. The travel times provide strong evidence for compressional velocity anisotropy in the upper crust corresponding to ∼10% faster velocities for propagation parallel to the axis than perpendicular to the axis; the travel tunes used for the tomography are corrected for the effects of this azimuthal anisotropy. Our preferred model contains only the structure clearly required by the data (structure which is stable under excessive smoothing) and achieves a variance reduction of 81% relative to the laterally homogeneous starting model. We resolve a substantial zone beneath the rise axis in which the velocity is reduced by 0.4 to 0.7 km/s; this low-velocity zone (LVZ) is about 7 km wide and extends from a depth of about 1.5–2.0 km down to Moho at a depth of 5.5 km. The LVZ is slightly asymmetric, extending 1 km further to the east than to the west of the axis. In the shallow (<1.0 km depth) crust, a pattern of velocity variations is imaged in which velocities are high at the spreading axis, decrease between 3 km and 7 km east of the axis, and then increase again between 10 and 15 km east of the axis. We investigate the resolution of the inversion using an impulse response method; the LVZ and off-axis upper crustal variations are well resolved. In addition, the travel time data indicate that an axial high-velocity anomaly less than 2 km wide exists in the upper crust but is not resolved by the inversion. The small velocity reductions of the LVZ are consistent with hot rock containing only a small quantity of melt. These results, combined with the multichannel seismic reflection lines and expanded spread profiles from the northern EPR, suggest that the zone of high melt fraction under the spreading center is confined to a narrow, thin lens capping a broad zone of hot plutonic rocks. The upper crustal velocity reduction within 1 km of the axis reflects near-axial thickening of the extrusive layer and the later reduction probably reflects porosity increases due to near-axial tectonism; the upper crustal velocity increase beyond 15 km off axis is attributed to porosity decreases associated with hydrothermal alteration.
Knowledge and Awareness of Rare Diseases Among Healthcare Professionals in the Kingdom of Bahrain

Aim Recent studies highlighted that lack of knowledge on rare diseases is a problem that requires attention. This study aims to assess healthcare professionals' general awareness and knowledge of rare diseases in a tertiary hospital in the Kingdom of Bahrain. Method The study employed a cross-sectional design, utilizing a survey questionnaire derived from the most recent literature. The survey encompassed socio-demographic factors and quiz-based questions that were previously created by Domaradzi and Walkowiak to assess knowledge and awareness of rare diseases. To ensure convenience and accessibility, the survey was made available in both Arabic and English languages. Results Of a total of 333 responses, 25.2% were physicians, 53.8% were nurses, and 21.0% were allied health personnel. The majority of participants (87.4%) were aware of and had heard the term "rare diseases" prior to this survey. Participants were able to recognize what age group is frequently affected by rare diseases (p=0.023) and what the common cause of rare diseases worldwide is (p<0.001). Overall scores showed that only four participants answered all questions correctly, testing their knowledge of rare diseases. There was a weak correlation between self-declared knowledge and the overall score achieved (r=0.190; p<0.001), which indicates that the population's self-declared knowledge did not portray their actual knowledge of rare diseases. Conclusion This study highlights the need for improved knowledge of rare diseases among healthcare professionals, which aligns with the global knowledge landscape. To bridge the knowledge gap, we recommend action plans to ensure that healthcare professionals have rich knowledge of rare diseases and further improve patient care. Additionally, enhancing advocacy efforts is crucial to ensure optimal local and global patient care services.
Acriflavine, a HIF-1 inhibitor, preserves vision in an experimental autoimmune encephalomyelitis model of optic neuritis

Introduction Optic neuritis (ON) is often an early sign of multiple sclerosis (MS), and recent studies show a link between HIF-1 pathway activation and inflammation. This study aimed to determine if inhibition of the HIF-1 pathway using the HIF-1a antagonist acriflavine (ACF) can reduce clinical progression and rescue the ocular phenotype in an experimental autoimmune encephalomyelitis (EAE) ON model. Methods EAE-related ON was induced in 60 female C57BL/6J mice by immunization with MOG33-55, and 20 EAE mice received daily systemic injections of ACF at 5 mg/kg. Changes in the visual function and structure of ACF-treated EAE mice were compared to those of placebo-injected EAE mice and naïve control mice. Results ACF treatment improved motor–sensory impairment along with preserving visual acuity and optic nerve function. Analysis of retinal ganglion cell complex alsoshowed preserved thickness correlating with increased survival of retinal ganglion cells and their axons. Optic nerve cell infiltration and magnitude of demyelination were decreased in ACF-treated EAE mice. Subsequent in vitro studies revealed improvements not only attributed to the inhibition of HIF-1 butalso to previously unappreciated interaction with the eIF2a/ATF4 axis in the unfolded protein response pathway. Discussion This study suggests that ACF treatment is effective in an animal model of MS via its pleiotropic effects on the inhibition of HIF-1 and UPR signaling, and it may be a viable approach to promote rehabilitation in MS.
Diagnostic Value of Preoperative uPAR-PET/CT in Regional Lymph Node Staging of Oral and Oropharyngeal Squamous Cell Carcinoma: A Prospective Phase II Trial

The detection of lymph node metastases is a major challenge in oral and oropharyngeal squamous cell carcinoma (OSCC and OPSCC). 68Ga-NOTA-AE105 is a novel positron emission tomography (PET) radioligand with high affinity to urokinase-type plasminogen activator receptor (uPAR), a receptor expressed on the surfaces of tumor cells. The aim of this study was to investigate the diagnostic value of uPAR-PET/CT (computerized tomography) in detecting regional metastatic disease in patients with OSCC and OPSCC compared to the current imaging work-up. In this phase II trial, patients with OSCC and OPSCC referred for surgical treatment were prospectively enrolled. Before surgery, 68Ga-NOTA-AE105 uPAR-PET/CT was conducted, and SUVmax values were obtained from the primary tumor and the suspected lymph nodes. Histology results from lymph nodes were used as the standard of truth of metastatic disease. The diagnostic values of 68Ga-uPAR-PET/CT were compared to conventional routine preoperative imaging results (CT and/or MRI). The uPAR expression in resected primary tumors and metastases was determined by immunohistochemistry and quantified digitally (H-score). A total of 61 patients underwent uPAR-PET/CT. Of the 25 patients with histologically verified lymph node metastases, uPAR-PET/CT correctly identified regional metastatic disease in 14 patients, with a median lymph node metastasis size of 14 mm (range 3–27 mm). A significant correlation was found between SUVmax and the product of the H-score and tumor depth (r = 0.67; p = 0.003). The sensitivity and specificity of uPAR-PET/CT in detecting regional metastatic disease were 56% and 100%, respectively. When added to CT/MRI, uPAR-PET was able to upstage 2/11 (18%) of patients with occult metastases and increase the sensitivity to 64%. The sensitivity and specificity of 68Ga-NOTA-AE105 uPAR-PET/CT were equivalent to those of CT/MRI. The significant correlation between SUVmax and uPAR expression verified the target specificity of 68Ga-NOTA-AE105. Despite the target specificity, the sensitivity of imaging is too low for nodal staging and it cannot replace neck dissection.
Salinity Variations in the Southern California Current

Abstract Hydrographic observations southwestward of the Southern California Bight in the period 1937–99 show that temperature and salinity variations have very different interannual variability. Temperature varies within and above the thermocline and is correlated with climate indices of El Nino, the Pacific decadal oscillation, and local upwelling. Salinity variability is largest in the surface layers of the offshore salinity minimum and is characterized by decadal-time-scale changes. The salinity anomalies are independent of temperature, of heave of the pycnocline, and of the climate indices. Calculations demonstrate that long-shore anomalous geostrophic advection of the mean salinity gradient accumulates along the mean southward trajectory along the California Current and produces the observed salinity variations. The flow anomalies for this advective process are independent of large-scale climate indices. It is hypothesized that low-frequency variability of the California Current system results from u.
Jovian Magnetospheric Injections Observed by the Hubble Space Telescope and Juno

We compare Hubble Space Telescope observations of Jupiter's FUV auroras with contemporaneous conjugate Juno in situ observations in the equatorial middle magnetosphere of Jupiter. We show that bright patches on and equatorward of the main emission are associated with hot plasma injections driven by ongoing active magnetospheric convection. During the interval that Juno crossed the magnetic field lines threading the complex of auroral patches, a series of energetic particle injection signatures were observed, and immediately prior, the plasma data exhibited flux tube interchange events indicating ongoing convection. This presents the first direct evidence that auroral morphology previously termed “strong injections” is indeed a manifestation of magnetospheric injections, and that this morphology indicates that Jupiter's magnetosphere is undergoing an interval of active iogenic plasma outflow.
Quantified vertical motions and tectonic evolution of the SE Pyrenean foreland basin

Abstract Local isostatic backstripping analysis is performed across the eastern part of the Ebro foreland basin between the Pyrenees and the Catalan Coastal Ranges. The subsidence analysis is based on two well-dated field-based sections and four oil-wells aligned parallel to the tectonic transport direction of the eastern Pyrenean orogen. The marine infill of the foreland basin is separated into four, third-order, transgressive-regressive depositional cycles. The first and second depositional cycles are located in the Ripoll piggy-back basin and the third and fourth ones are located south of the syn-depositional emergent Vall-fogona thrust. Subsidence curves display a typical convex-up shape with inflection points recording the onset of rapid tectonic subsidence. Inflection points coincide roughly with the base of depositional cycles. Rates of tectonic subsidence are less than 0.1 mm a−1 in distal parts of the basin and up to 0.53 mm a−1 in proximal parts during second depositional cycle. Younger depositional cycles show maximum rates of tectonic subsidence of 0.26 mm a−1. The locus of subsidence within the basin migrated southward at a rate of c. 10 mm a−1. This flexural wave crossed the complete Ebro foreland basin in 10–11 Ma. The intraplate Catalan Coastal Ranges at the southeastern margin of the Ebro foreland basin produced an increase of tectonic subsidence rate at 41.5 Ma. Maximum rates of tectonic subsidence coincide with deep-marine infill of the basin, maximum rates of shortening and thrust front advance, and low topographic relief orogenic wedge. Transgressive-regressive depositional cycles can be controlled partly by reductions of available space within the basin during tectonic thickening of the sedimentary pile by layer parallel shortening, folding and thrusting. Although much less constrained, an approximation of post-thrusting exhumation and isostatic and tectonic uplift, as well as a first determination of possible amounts of eroded material of parts of the Ebro basin illustrate the impact of post-depositional erosion and uplift on the foreland.
Disabled beggars in Addis Ababa, Ethiopia

This study brings together qualitative and quantitative data to better understand the lives of people with disabilities who beg in Ethiopia. It sets out to provide an initial understanding of the lives of disabled beggars with particular emphasis on determining social and economic factors, and sequences of events or patterns of behaviour that are common to people with disabilities who now work as beggars. Chapter 3 provides an overview of the demographic characteristics of the survey respondents, including their education and vocational training levels and work history. Additional attention was directed to identifying possible areas of intervention that might sever the links between disability and poverty. The study yielded an intriguing set of results that identify: the complex set of issues with which disabled beggars grapple; a series of points where targeted intervention by governments, UN agencies, NGOs and disabled people's organizations could help break the on-going cycle of disability and poverty; and choices that lead some men and women with disabilities to beg. The study contains recommendations for policy, programming and areas for further research.
Mathematical analysis of epidemic model to assess the impact of lockdown on COVID-19

Covid-19 and its variants, have been a worst pandemic, the entire world has witnessed. Tens of millions of cases have been recorded in over 210 countries and territories as part of the ongoing global pandemic that is still going on today. In this paper, we propose a SEI mathematical model to investigate the impact of lockdown to the controlling and spreading of infectious disease COVID-19. The epidemic model incorporates constant recruitment, experiencing infectious force in the latent period and the infected period. The equilibrium states are computed. Under some conditions, results for local asymptotic stability and global stability of disease-free and endemic equilibrium are established by using the stability theory of ordinary differential equations. It is seen that when the basic reproduction number , the dynamical system is stable and diseases die out from the system and when , the disease persists in the dynamical system. When , trans critical bifurcation is appeared. The numerical simulations are carried out to validate the analytical results.
CONTRIBUTION TO THE SPELEOLOGY OF STERKFONTEIN CAVE, GAUTENG PROVINCE, SOUTH AFRICA

The authors present more data about the speleological aspect of the Sterkfontein Cave, famous for its bone breccia which yielded abundant hominid remains. They also briefly review the previous voluminous studies by numerous authors, which are mainly dealing with the paleontology, stratigraphy and sedimentology of the breccia. The present investigations were oriented to hitherto poorly investigated aspects such as detail mapping of the cave, its country rock stratigraphy and recording the underground extension of the basal part of the breccia body. The cave consists of a complex network of phreatic channels, developed along joints in Neoarchaean cherty dolostone over a restricted surface of 250x250m. The combined length of all passages within this area amounts to 5,23km. The system extends over a height of about 50m and the dry part of it is limited downwards by the water-table appearing as numerous static pools. The fossiliferous breccia (= Sterkfontein Formation) forms an irregular lenticular mass 75x25m horizontally by 40m vertically, which is included within the passage network. It crops out at surface and in the cave, and resulted from the filling of a collapse chamber, which was de-roofed by erosion. The present investigation confirmed that the cave and the Sterkfontein Formation are part of a single speleogenetic event. The breccia resulted from cavity filling by sediments introduced from a pit entrance, whereas many of the phreatic passages around it, which are developed at the same elevation, were only partly filled or remained entirely open up to present. This filling took place mainly in a vadose environment. Taking into account the age of the Sterkfontein Formation (>3,3-1,5 My, from base to top), the geomorphic evolution of the landscape and the context of other caves in the region, it seems that the cave might have started to form 5 My ago. It has been continuously developing up to present as a result of a slow drop of the water-table.