Miracle-dz/UniFAR-FTUs huggingface dataset:
Computational Study of Halide Perovskite-Derived A2BX6 Inorganic Compounds: Chemical Trends in Electronic Structure and Structural Stability

The electronic structure and energetic stability of A2BX6 halide compounds with the cubic and tetragonal variants of the perovskite-derived K2PtCl6 prototype structure are investigated computationally within the frameworks of density-functional-theory (DFT) and hybrid (HSE06) functionals. The HSE06 calculations are undertaken for seven known A2BX6 compounds with A = K, Rb, and Cs; and B = Sn, Pd, Pt, Te, and X = I. Trends in band gaps and energetic stability are identified, which are explored further employing DFT calculations over a larger range of chemistries, characterized by A = K, Rb, Cs, B = Si, Ge, Sn, Pb, Ni, Pd, Pt, Se, and Te; and X = Cl, Br, I. For the systems investigated in this work, the band gap increases from iodide to bromide to chloride. Further, variations in the A site cation influences the band gap as well as the preferred degree of tetragonal distortion. Smaller A site cations such as K and Rb favor tetragonal structural distortions, resulting in a slightly larger band gap. For varia.
Changes in prevalence and causes of visual impairment and cataract surgical coverage in Nampula, Mozambique between 2011 and 2018: findings from two cross-sectional surveys

Background Globally, there are few examples of repeated eye health surveys to assess changes in prevalence and causes of visual impairment, and service coverage over time. Two separate, unlinked rapid assessments of avoidable blindness (RAAB) were conducted in Nampula province, Mozambique in 2011 and 2018. This paper reports the observed changes and examines how the trends differ for males and females. Methods Standard RAAB methodology was used in both studies. Two-stage cluster sampling was used to generate random samples of adults aged over 50 years. Participants underwent a simplified visual acuity exam focusing on presenting and pinhole visual acuity (VA), a lens exam and posterior segment exam using a direct ophthalmoscope for all subjects with presenting VA < 6/18. Data were analysed using Stata and logistic regression models were developed to assess changes. Results The 2011 study enrolled 3,050 people and examined 96.9% (2,954 people). The 2018 survey enrolled 4,191 people and examined 95.8% (4,015 people). Age and sex adjusted estimates of blindness decreased from 6.2% in 2011 to 4.5% in 2018 (z=-2.21, p = 0.028), severe visual impairment remained the same (2.6% in 2011 and 2.7% in 2018, z = 0.1, p = 0.9) and moderate visual impairment increased (5.9% in 2011 to 11.0% in 2018, z = 5.78, p < 0.001). Cataract surgical coverage was higher among males in both surveys (13.4% among males vs 7.7% among females in 2011, and 40.0% among males vs 19.4% among females in 2018) and the gender disparity grew between surveys. Conclusions Significant changes were observed in the eye health and service coverage between 2011 and 2018. An increase in the proportion of good visual acuity among operated eyes between the surveys is of note and may correspond with improvements made to the services provided in the province. Further improvements to services are required to improve access for women and people with moderate visual impairment.
Lack of knowledge and awareness on cervical cancer vaccination hinders the administration of HPV vaccination among the health care professionals.

Background: Cervical cancer is the second most common cancer among females in India. This study was conducted regarding current awareness about cervical cancer, which is helpful in designing educational programs and to overcome barriers associated for knowledge enhancement about cervical cancer and its screening & vaccination. Methods : This is a cross-sectional study conducted among 318 health care professionals working in tertiary hospitals across Chennai, Tamil Nadu, India. A semi-structured questionnaire with 31 items was developed by the researchers to explore the knowledge and attitudes on cervical cancer, cervical cancer prevention and HPV(Human Papilloma Virus)vaccination. Results: Among the 318 respondents, 90.6% were aware of cervical cancer, but only 29.2% had done screening against cervical cancer and 19.8% got vaccinated. 94.7% of the study subjects heard of HPV and 86.2% knew that HPV causes cervical cancer. 83.3% people knew that PAP( Papanicolaou) smear test detects the cervical cancer. But, only 29.2% had PAP test. 68.2% of the study subjects knew that cancer cervix can be prevented by vaccination. But only 19.8% got vaccinated . Only 34.9% know that HPV vaccine can be given to boys. Most common reason for not getting vaccination was lack of awareness. 77.2% in our study are willing for vaccination and recommendation to their friends and family members. Conclusion: Lack of awareness with regard to the cervical cancer could be the possible hurdle for the HPV vaccination among the health professionals.
Environmentally sensitive hydrogel functionalized with electroactive and complexing‐iron(III) catechol groups

Thermoresponsive pNIPA (poly (N-isopropylacrylamide)) gels modified with dopamine methacrylamide were synthesized using free-radical polymerization. In this way, the catechol groups were introduced into the polymer network. The presence of dopamine in the gel led to a significant shift in the volume phase transition temperature (VPTT). It was found that hydrogels were electroactive and that oxidation of catechol groups also led to a strong shift in the VPTT. The temperature window, that is, the range of temperature where volume of the gel could be substantially changed by oxidation of the catechol groups, for the gel formed from the polymerization solution containing 5% of the dopamine derivative, was 30–40 °C. Additionally, the influence of Fe3+ ions, which form the most stable complexes with dopamine, on swelling behavior of the gels was investigated at various pH. © 2017 Wiley Periodicals, Inc. J. Polym. Sci., Part A: Polym. Chem. 2017
Analysing Dynamic Change in Children’s Socio-Emotional Development using the Strengths and Difficulties Questionnaire in a large UK Longitudinal Study

Background: Most mental health difficulties have their onset during childhood and adolescence. Many children who suffer from one mental health issue also suffer from at least one co-occurring disorder. Autoregressive latent trajectory models with structured residuals (ALT-SR) and multilevel graphical vector autoregression (GVAR) are recent complementary approaches that can help provide new insights into the reciprocal relationships between multiple mental health domains and advance the understanding of the development of comorbidities.Methods: This study uses ALT-SR and multilevel GVAR models to analyse the temporal, contemporaneous and between-person relationships between emotional problems, peer problems, conduct problems, hyperactivity/inattention and prosociality as measured by the parent-reported Strengths and Difficulties Questionnaire (SDQ) in 17,478 children taking part in the UK Millennium Cohort Study at ages 3, 5, 7, 11, 14 and 17 years. Results: Results from both the ALT-SR and the multilevel GVAR model highlight that children’s strengths and difficulties in different domains of psychosocial functioning are dynamically associated with each other over- and within-time. The ALT-SR highlighted that hyperactivity/inattention plays a central role in affecting other domains over developmental time while the GVAR model highlighted comparably strong bidirectional relationships between conduct problems and prosociality as well as between emotional problems and peer problems. Conclusion: This study highlights that mental health difficulties influence one another dynamically over time. As illustrated in the domains of the SDQ, these dynamic changes can be modelled using the complementary techniques of ALT-SR or GVAR models, each offering different insights into the nature of comorbidity.
The Effect of the Country of Origin on Chinese Smartphone Purchase Intention

: This research aims to examine several factors that is impacted towards smartphone purchase intention. A survey through questionnaire with 200 accounting students has been conducted in this research. Each statement measured by a questionnaire where shared with Google docs. Total of samples in this research is about 200 respondents where that is students with major accounting on five colleges in Batam city. Result shows that country image has positive effect towards purchase intention, product perceived quality has positive effect towards purchase intention, and brand familiarity has positive effect towards purchase intention. This research is limited only by accounting students, the writer hopes that similar studies further will expand the research sample so the research can be generalized.
Test Anxiety: A Case of ESL Vocabulary Testing Using Multiple-Choice Items and Error Identification Tests

The current study seeks to discern the impact of test anxiety on English language students’ test performance. The major instruments which helped gathering data were two different formats of vocabulary test and a questionnaire survey which identified the level of anxiety. Participants were fifty female English language learners who were studying at intermediate and upper-intermediate levels of English. These students were grouped into two groups of MC and EI according to their scores in the examinations they were given in the pre-test phase, multiple-choice test and error identification test. The survey after the pre-test indicated the level of anxiety these tests have brought. During a span of twenty-week period students received different teaching plans respectively. The same tests in pre-test were administered in the post-test phase and the questionnaire illustrated the level of anxiety after each student has received particular treatment. The findings showed that the level of test anxiety is higher in the group which received and tested on error identification format of vocabulary knowledge test. This increase of test anxiety was by definition significant in comparison with the other group, MC. The other important part of this study was coming to this conclusion that while students were given their particular teaching plans, debilitative anxiety still impedes them from having a strong and high performance which in turn needs more considerations from their teachers and examiners.
Understanding Patterns of Healthy Aging Among Men Who Have Sex With Men: Protocol for an Observational Cohort Study

Background With the graying of sexual and gender minority communities and the growing number of people aged ≥50 years living with HIV, it is increasingly important to understand resilience in the context of the psychosocial aspects of aging and aging well. Objective This paper aims to describe the methods and sample for the Understanding Patterns of Healthy Aging Among Men Who Have Sex With Men study. Methods This observational cohort study was conducted within the Multisite AIDS Cohort Study (MACS) and was designed to explore resiliencies to explain patterns of health and illness among middle-aged and older sexual minority men. To be eligible, a participant had to be an active participant in the MACS, be at least 40 years of age as of April 1, 2016, and report any sex with another man since enrollment in the MACS. Results Eligible participants (N=1318) completed six biannual surveys between April 2016 and April 2019. The mean age of the sample was 59.6 years (range 40-91 years). The sample was mostly White, educated, gay-identified, and included both HIV-positive (656/1318, 49.77%) and HIV-negative (662/1318, 50.23%) men. Conclusions Understanding resiliencies in aging is a critical springboard for the development of more holistic public health theories and interventions that support healthy aging among older sexual minority men. International Registered Report Identifier (IRRID) RR1-10.2196/25750
The Effect of Service Quality on Loyalty of Tri Indonesia Cellular Operator

This research was conducted to explain service quality as the main factor that determines the level of customer satisfaction in service quality dimensions. In addition, this research investigates whether the level of service quality provided by Tri Indonesia can increase customer satisfaction in using Tri cellular operator. The respondents of this research were Tri cellular operator users in Indonesia which were divided into three regions with a total sample of 400 respondents and conducted using non-probability sampling technique. Data processing tools was PLS-SEM and the findings indicated that there was a significant effect between service quality and loyalty. Moreover, this research can be used as a competitive strategy with business competitors, and can measure the quality performance provided by companies by looking at the level of consumer loyalty.
Penggunaan Digital Marketing untuk Memperluas Pasar dan Meningkatkan Daya Saing UMKM

Salah satu permasalahan yang membuat daya saing UMKM masih rendah adalah terbatasnya kemampuan para pelaku usaha dalam melakukan pemasaran. Kegiatan pengabdian pada masyarakat ini dilaksanakan untuk mengenalkan produk UMKM keripik singkong ke pasar yang lebih luas, meningkatkan daya saing UMKM melalui pemanfaatan digital marketing. Dalam pengabdian ini, metode yang digunakan untuk memecahkan permasalahan adalah memberikan penyuluhan, pelatihan, dan pendampingan kepada pelaku UMKM yang menjadi mitra. Kegiatan tersebut dilaksanakan secara bertahap selama 2 bulan. Dari kegiatan yang telah dilaksanakan, mitra cukup memahami tentang konsep digital marketing dan mampu menggunakan internet untuk melakukan pemasaran. Meningkatnya kemampuan mitra dalam melakukan pemasaran diharapkan dapat membantu mitra untuk memperoleh pasar yang lebih luas dan meningkatkan daya saing mitra sebagai pelaku UMKM
Modelling Amyloidosis in Mice

Amyloidosis is a group of disorders in which specific soluble proteins convert into insoluble extracellular fibrillar deposits. Certain mutations in amyloid prone proteins result in aggressive forms of the disease. β2-microglobulin (β2m), a cell surface protein and transthyretin (TTR), a normal plasma protein, are inherently amyloidogenic. In patients undergoing long-term dialysis, ineffective clearance of β2m from the plasma results in sustained increase of its concentration and its deposition as amyloid. Wild type TTR is the amyloid precursor in senile systemic amyloidosis, a cause of heart failure in the elderly, and various different mutations in the human TTR gene cause the autosomal dominant conditions familial amyloid polyneuropathy and familial amyloid cardiomyopathy. The D76N β2m variant causes highly penetrant hereditary systemic amyloidosis. Similarly, the S52P TTR variant also causes aggressive amyloidosis which is characterised by prominent cardiac ATTR deposits. Animal models for Aβ2m amyloidosis and ATTR amyloidosis have long been sought to enable a better understanding of disease mechanisms and for validation of diagnostic methods and treatments, but previous attempts to model these diseases in vivo have met with limited or no success. The aims of this project were to generate mouse models of: (1) Aβ2m amyloidosis and (2) cardiac ATTR amyloidosis by transgenic expression of these highly amyloidogenic variants. In the work presented here, hβ2mD76N transgenic mice and hTTRS52P transgenic mice were generated. Despite expressing high plasma concentrations of the amyloidogenic proteins, the mice did not spontaneously develop amyloidosis. After priming amyloid deposition with pre formed amyloid fibrils, the hβ2mD76N transgenic mice failed to develop amyloid deposits. It is notable that most of the β2m circulates bound in a complex, potentially limiting the availability of free β2m monomers for conversion into fibrils. In the hTTRS52P transgenic mice, priming of amyloid deposition with amyloid fibrils led to consistent and reproducible development of cardiac ATTR amyloidosis.
Repurposing combination therapy of Voacamine with Vincristine for down regulation of HIF-1α/FASN co-axis and PHD2 activation in ER+ mammary neoplasia

Background The current study was attempted to inquest the role of combination therapy of Voacamine and Vincristine for the prevention of mammary gland carcinoma through prolyl hydroxylase-2 activation. The prolyl hydroxylase‐2 activation leads the downregulation of hypoxia‐inducible factor‐1α and fatty acid synthase. Over expression of hypoxia inducible factor-1α and fatty acid synthase is previously reported in solid tumor of mammary gland. Methods After screening a battery of natural compounds which were similar to vincristine, vocamine was selected as a possible prolyl hydroxylase-2 activator and justify its activity using 7, 12-Dimethylbenz[a]anthracene induced rat model. The combination therapy was evaluated for cardiac toxicity using hemodynamic profile. The angiogenic markers were evaluated using carmine staining. Monotherapy and combination therapy were also evaluated for liver and kidney toxicity through haematoxylin and eosin staining. The combination therapy also delineated the markers of oxidative stress favorably. Afterwards, the disruption of fatty acids was evaluated using gas chromatography. Results The immunoblotting analysis validated that combination therapy has a potential to switch on the prolyl hydroxylase-2 activity and thus initiate proteolytic degradation of hypoxia‐inducible factor‐1α and its consequence effects. The combination therapy also stimulated programmed cell death (apoptosis) in rapidly dividing cancer cells. Conclusion The present study explores the role of voacamine in activation of prolyl hydroxylase-2 which can decrease over expression of hypoxia‐inducible factor‐1α and fatty acid synthase in cells of mammary gland carcinoma.
Nutraceuticals Induced Structural Changes in Broiler Gastrointestinal Tract Microbiota

Background The effects of nutraceuticals on the modulation of the intestinal microbiota are receiving increased attention however there are scarce number of studies investigating their effects in broiler meat production. The aim of this study was to implement feeding strategies and carry out a comprehensive trial on the interplay between carotenoids, anthocyanins, fructo-oligosaccharides, probiotics and gastrointestinal tract microbiota. Our feeding program was applied on an intensive production system with 1080 broiler Ross 308 flock.Results We observed that nutraceuticals and synbiotics did not affect growth performance remarkably nevertheless, positive correlation was found between body weight and the beneficious Bacteroidales, Corynebacteriales and Pseudomonadales. Nutraceuticals were shown to boost broiler intestinal diversity and differentially enriched Lactobacillus, Enterococcus, Streptococcus and Escherichia-Shigella in core microbiome during the different stages of broiler rearing. Furthermore, diet supplemented with different nutraceuticals was shown to increase the number of unique beneficial bacteria (Faecalibacterium, Akkermansia). Conclusion We concluded that nutraceutical-based feeding strategies can offer a promising, green approach for intensive poultry rearing by improving the health and production of livestock. We believe that the conversion of food industrial waste would result more sustainable bioactive component rich forages which invention could be implemented by other commercial antibiotic-free animal production system providing safe and quality meat.
Structure of turbulent rich hydrogen‐air premixed flames

In the present article, series of experiments were conducted to study the structure characteristics of premixed flames in turbulent rich hydrogen‐air mixtures within a constant‐volume turbulent combustion system, 7 equivalence ratios (1.2, 1.4, 1.6, 1.8, 2.0, 2.2, and 2.5), and 5 turbulent intensity (0, 0.494, 0.742, 1.080, and 1.309 m/s) were studied. With the increase of turbulent intensity, the cellularity degree was obviously enhanced for turbulence promoted the formation and the development of initial cracks by wrinkling flame‐front; furthermore, the enhanced hydrodynamic instability was also one important reason. Turbulence would change the linear growth of critical radius to equivalence ratio into nonlinear, but the variation extents had limitation. The wrinkling index of flame‐front would rise as flame expanded, and the wrinkling index on flames with similar size would be increased with the increase of turbulence once the turbulent intensity was sufficiently high. From the variations of the root mean square of related oscillation on flame‐front, it could be found that the partial amount of oscillation induced by sole turbulence was declined as flame expanded for the breakup of large eddies.
Influences of the Cu Substitution at Hg Site in Hg1 - xCuxBa2Ca2Cu3O8+δSuperconductors

The influences of the Cu substitution at Hg site in the HgOd layer, upon the microstructure, Tc and oxygen content of Hg-1223 have been investigated. High temperature superconductor with a nominal composition Hg1-xCuxBa2Ca2Cu3O8 + δ for Cu ( 5 . 0 0 £ £ x ) have been prepared by the two-steps solid state reaction method under optimum conditions. XRD showed a tetragonal structure with a high ratio of Hg-1223 superconductor phase. Tc enhancement has been determined with the Cu concentration was is found to be Tc = 153 K for x = 0.3, while the oxygen content observed variously with Cu concentration. Hg 1-xCuxBa2Ca2Cu3O8+δ structure, oxygen content and Tc behavior have been discussed.
Evaluation of Heavy Metal Tolerance Level (MIC) and Bioremediation Potentials of Pseudomonas aeruginosa Isolated from Makera-Kakuri Industrial Drain in Kaduna, Nigeria

Bacterial strains isolated from the Kakuri drain were characterized and subjected to various concentrations of heavy metal salts and their ability to tolerate the heavy metals (Minimum Inhibitory Concentration-MIC) was determined. This shows their ability to tolerate and survive in environments with high levels of heavy metal salts. Eight(8) heavy metals were considered , and included ; Cobalt Chloride (CoCl2), Cadmium Chloride (CdCl2),Copper Sulphate (CuSo4), Mercury Chloride (HgCl2), Nickel Chloride (NiCl2), Potassium Dichromate (K2Cr207), Lead Chloride (PbCl2) and Zinc Sulphate (ZnS04). Strains were subjected to varied millimolar concentrations (1, 2, 5, 10, 20, 30 and 50 mM). Positive and Negative controls were set up to a certain the tolerance level amongst the strains. 100% growth of all strains was observed at 1 mM concentration, while 100% growth was recorded with CuS04, ZnS04 and HgCl2. Most strains were inhibited or could not tolerate the salts at 10 mM concentration, with the exception of ZnS04, PbCl2, and CdCl2. No growth (100% inhibition) was noticed on plates with 20, 30, 40 or 50 mM concentrations. It therefore shows that the strains isolated from the kakuri drain could withstand presence of heavy metals salts up to a concentration of 10 mM.