Miracle-dz/UniFAR-FTUs huggingface dataset:
Correlation of the mechanical and structural properties of trabecular bone assessed by wave propagation and imaging methods

This study aimed to assess the correlation of the location- and direction-dependent mechanical and structural properties of trabecular bone using the wave propagation and imaging methods and to propose a non-invasive approach for the assessment of the quality of trabecular bone. Two bovine femur trabecular bone specimens were prepared and tested using the Rayleigh wave propagation tests and CT-scan imaging. The elastic modulus of the specimens was estimated in different regions of interest (ROIs) and wave propagation directions by the solution of the presented Rayleigh wave propagation model. The structural parameters of the specimens were also obtained via the processing of CT-scan images for all of the tested ROIs and directions. The estimated elastic modulus was in the range between 321and 1322 MPa for different ROIs and directions, showing significant heterogeneity and anisotropy of the bone specimens. The Pearson correlation and linear regression analyses were carried out between the obtained mechanical and structural properties, which revealed that the elastic modulus decreased with the trabecular separation and increased with the trabecular thickness and bone volume fraction. A semi-empirical relation was developed to obtain the elastic modulus of trabecular bone using the structural parameters obtained from imaging or vice versa.
Transferability Intercomparison: An Opportunity for New Insight on the Global Water Cycle and Energy Budget

A new approach, called transferability intercomparisons, is described for advancing both understanding and modeling of the global water cycle and energy budget. Under this approach, individual regional climate models perform simulations with all modeling parameters and parameterizations held constant over a specific period on several prescribed domains representing different climatic regions. The transferability framework goes beyond previous regional climate model intercomparisons to provide a global method for testing and improving model parameterizations by constraining the simulations within analyzed boundaries for several domains. Transferability intercomparisons expose the limits of our current regional modeling capacity by examining model accuracy on a wide range of climate conditions and realizations. Intercomparison of these individual model experiments provides a means for evaluating strengths and weaknesses of models outside their “home domains” (domain of development and testing). Reference si.
Impact of the Madden–Julian Oscillation on Western North Pacific Tropical Cyclogenesis Associated with Large-Scale Patterns

AbstractThe intraseasonal variability of tropical cyclogenesis in the western North Pacific (WNP) basin is explored in this study. The relation of cyclogenesis in each of the five large-scale patterns identified in recent work by Yoshida and Ishikawa is associated with the Madden–Julian oscillation (MJO). Confirming previous results, more events of cyclogenesis are found during the active MJO phase in the WNP. Furthermore, results indicate that most of the tropical cyclogenesis is associated with the monsoon shear line large-scale pattern during the active phase. The genesis potential index (GPI) and its individual components are used to evaluate the environmental factors that most contribute toward cyclogenesis under the different phases of the MJO. GPI exhibits a large positive anomaly during the active phase of the MJO, and such an anomaly is spatially correlated with the events of cyclogenesis. The analysis of each factor indicates that low-level relative vorticity and midlevel relative humidity are t.
The dynamics of a viscous vortex dipole

The structure of a two-dimensional viscous dipole is accurately analyzed using both numerical simulations and theoretical analyses. First, a model is proposed, which computes the dipole velocity and the vortex ellipticity based on a heuristic relation between a vortex patch and a vortex with distributed vorticity profile. Second, during the stage where vortices are close to each other, a generalized self-similar solution is postulated to describe the vorticity profiles observed during the viscous spreading of the dipole. Numerical as well as theoretical considerations are given, which demonstrate the adequacy of such a hypothesis. Finally the structure of the tail that is generated behind the dipole is given in an analytical form, which favorably compares to numerical results.
Scaffolding Self-Regulation in an Online English Language Course: Utility of Contract Learning

As students’ achievement is correlated with self-regulation, finding interventions promoting self-regulated learning (SRL) in online courses is a current focus of research. However, few studies have explored the potential of contract learning in scaffolding and developing SRL in non-traditional learners who have work and family and are at risk of dropout. Here, we investigate the utility of contract learning using a qualitative approach. Using a qualitative approach, we collected data from the experience of one teacher and seven non-traditional learners in an online English for Specific Purposes (ESP) course. The data were collected from teacher logs over eight months and semi-structured interviews with the students. The results of deductive thematic analysis of the data indicate that contract learning positively affected the forethought, performance, and self-reflection phases. Further, despite the cognitive, emotional, external, motivational, and behavioral challenges aggravated by the pandemic, the teacher’s efforts to implement contract learning affected the persistence and effort, goal setting, strategic planning, and time management of most learners (N = 4). Possible reasons for the learners’ success and failure and the implications for developing SRL skills in students at risk of dropout in online English courses are discussed.
The Relationship Between Horizontal and Vertical Velocity Wavenumber Spectra in Global Storm-resolving Simulations

Several studies have reported vertical kinetic energy spectra almost white in horizontal wavenumber space with evidence of two maxima at synoptic scales and mesoscales, leaving the explanation of these maxima open. Processes known to influence the shape of the horizontal kinetic energy spectra include the superposition of quasi-linear inertia-gravity waves (IGWs), quasigeostrophic turbulence, and moist convection. In contrast, vertical kinetic energy has been discussed much less, as measuring vertical velocity remains challenging. This study compares the horizontal and vertical kinetic energy spectra and their relationships in global storm-resolving simulations from the DYAMOND experiment. The consistency of these relationships with linear IGW theory is tested by diagnosing horizontal wind fluctuations associated with IGW modes. Furthermore, it is shown that hydrostatic IGW polarization relations provide a quantitative prediction of the spectral slopes of vertical kinetic energy at large scales and mesoscales, where the intrinsic frequencies are inferred from the linearized vorticity equation. Our results suggest that IGW modes dominate the vertical kinetic energy spectra at most horizontal scales, whereas an incompressible, isotropic scaling of the continuity equation captures the relationship between horizontal and vertical kinetic energy spectra at small scales.
Dual-wavelength neodymium-doped yttrium aluminum garnet laser with chromium-doped yttrium aluminum garnet as frequency selector

We report on a potential source for the generation of terahertz radiation using the well-known neodymium-doped yttrium aluminum garnet as the laser material, and chromium-doped yttrium aluminum garnet (Cr:YAG) as the frequency selector and saturable absorber. Continuous-wave output power as high as 5.28 W at 1052 nm was achieved. With Cr:YAG, the laser has a dual-wavelength output at 1052 and 1064 nm. The maximum average output power, pulse repetition rate, and pulse energy are 3.75 W, 41.2 kHz, and 90.1 μJ, respectively. We also found that the intensity ratio of the two oscillating modes can be tuned by adjusting the pump power.
Path integral for gauge theories with fermions

The Atiyah-Singer index theorem indicates that a naive unitary transformation of basis vectors for fermions interacting with gauge fields is not allowed in general. On the basis of this observation, it was previously shown that the path-integral measure of a gauge-invariant fermion theory is transformed nontrivially under the chiral transformation, and thus leads to a simple derivation of ''anomalous'' chiral Ward-Takahashi identities. We here clarify some of the technical aspects associated with the discussion. It is shown that the Jacobian factor in the path-integral measure, which corresponds to the Adler-Bell-Jackiw anomaly, is independent of any smooth regularization procedure of large eigenvalues of D in Euclidean theory; this property holds in any even-dimensional space-time and also for the gravitational anomaly. The appearance of the anomaly and its connection with the index theorem are thus related to the fact that the primary importance is attached to the Lorentz-covariant ''energy'' operator D and that D and . gamma. /sub 5/ do not commute. The abnormal behavior of the path-integral measure at the zero-frequency sector in the presence of instantons and its connection with spontaneous symmetry breaking is also clarified. We comment on several other problems associated with the anomaly and on the Pauli-Villars regularization method.
Underwater sound radiated by bubbles released by melting glacier ice

Passive acoustics monitoring techniques have been examined as a method to remotely sense activity of glacier ice near the ice-ocean boundary [Ann. of Glaciology 53, 113-121 (2012)]. Sound from glacier calving events and the resultant breaking and bobbing of the ice after impact with the water ranges from infrasound ( 10kHz) generated by breaking tsunamis and seiches after impact. Bubbles are known to form within ice during glacier formation and can be released from glaciers as they undergo submarine melting. Due to the possibility of high internal bubble pressure, this release can occur in the form of jetting or squirting events. Signals hypothesized to be from bubbles being released from melting glacier ice were measured in at various field locations in Alaska using passive autonomous hydrophone moorings and near-surface recordings in the 1 kHz-3 kHz frequency range. To temporally and spatially correlate such acoustic emissions with bubble activity, a set of laboratory measurements was performed using small samples of glacier ice and acoustic emission was positively correlated with bubble release. Taken together, these measurements support the use of passive acoustics to monitor marine glacier ice melt.
A characterization of marginal distributions of (possibly dependent) lifetime variables which right censor each other

It is well known that the joint distribution of a pair of lifetime variables $X_1$ and $X_2$ which right censor each other cannot be specified in terms of the subsurvival functions $$P(X_2 > X_1 > x), \quad P(X_1 > X_2 > x)$ \quad \text{and} \quad $P(X_1 = X_2 > x)$$ without additional assumptions such as independence of $X_1$ and $X_2$. For many practical applications independence is an unacceptable assumption, for example, when $X_1$ is the lifetime of a component subjected to maintenance and $X_2$ is the inspection time. Peterson presented lower and upper bounds for the marginal distributions of $X_1$ and $X_2$, for given subsurvival functions. These bounds are sharp under nonatomicity conditions. Surprisingly, not every pair of distribution functions between these bounds provides a feasible pair of marginals. Crowder recognized that these bounds are not functionally sharp and restricted the class of functions containing all feasible marginals. In this paper we give a complete characterization of the possible marginal distributions of these variables with given sub-survival functions, without any assumptions on the underlying joint distribution of $X_1, X_2$. Furthermore, a statistical test for an hypothesized marginal distribution of $(X_1$ based on the empirical subsurvival functions is developed.
Weight Loss From Combination Anti-Obesity Medication Regimens Can Approach that Achieved From Bariatric Surgery

Abstract Obesity is a multifactorial chronic disease for which treatment remains challenging. While the cornerstone treatment is lifestyle modification, the addition of anti-obesity medications leads to greater weight reduction. In cases where monotherapy with a single anti-obesity medication results in either weight stabilization or only modest weight reduction, combination regimens can be highly effective, especially those including glucagon-like peptide-1 receptor agonists. We report the case of a 23-year-old male initially presenting with a body mass index of 84.3 kg/m2. In addition to lifestyle modification therapy, he was started on phentermine, topiramate, and metformin, which only resulted in weight stabilization after 1 year. Subsequently, semaglutide (a glucagon-like peptide-1 receptor agonist) was added, along with a lower calorie diet, which resulted in a 32.5% total body weight reduction, approximating that which can be achieved following metabolic/bariatric surgery. This case highlights the potential benefit of combination anti-obesity medication regimens including glucagon-like peptide-1 receptor agonists, as such regimens may provide a synergistic effect by targeting multiple eating behavior pathways simultaneously. Further studies are needed to evaluate the efficacy of combination anti-obesity medication regimens, especially among those achieving suboptimal response to monotherapies.
Tumor-Infiltrating Lymphocytes in Localized Prostate Cancer: Do They Play an Important Role?

Background Localized prostate cancer is a heterogeneous entity, and new biomarkers are required for risk stratification. This study aimed to characterize tumor-infiltrating lymphocytes (TILs) in localized prostate cancer and assess their potential prognostic markers. Methodology Radical prostatectomy specimens were analyzed to determine infiltration levels of CD4+, CD8+, T cells, and B cells (characterized by CD20+ cells) in the tumor tissue using immunohistochemistry and the recommendations of the International TILs Working Group 2014. The clinical endpoint was biochemical recurrence (BCR), and the study sample was divided into two cohorts (cohort 1: without BCR; cohort 2: with BCR). Prognostic markers were assessed using Kaplan-Meier and univariate/multivariate Cox regression analysis using SPSS version 25 (IBM Corp., Armonk, NY, USA). Results We included 96 patients in this study. BCR occurred in 51% of the patients. Normal TILs infiltration was found in most of the patients (41/31, 87%/63%). T CD4+ infiltration was statistically superior in cohort 2. This enrichment was associated with BCR (p < 0.05; log-rank test). After adjustment for routine clinical variables and Gleason grade groups (grade group ≤2 and grade group ≥3), it remained an independent prognostic variable of early BCR (p < 0.05; multivariate Cox regression). Conclusions This study showed that immune cell infiltration appears to be an important prognostic variable for early recurrence in localized prostate cancer.
Evaluation of the Cytotoxic Effect of Pd2Spm against Prostate Cancer through Vibrational Microspectroscopies

Regarding the development of new antineoplastic agents, with a view to assess the selective antitumoral potential which aims at causing irreversible damage to cancer cells while preserving the integrity of their healthy counterparts, it is essential to evaluate the cytotoxic effects in both healthy and malignant human cell lines. In this study, a complex with two Pd(II) centers linked by the biogenic polyamine spermine (Pd2Spm) was tested on healthy (PNT-2) and cancer (LNCaP and PC-3) prostate human cell lines, using cisplatin as a reference. To understand the mechanisms of action of both cisplatin and Pd2Spm at a molecular level, Fourier Transform Infrared (FTIR) and Raman microspectroscopies were used. Principal component analysis was applied to the vibrational data, revealing the major metabolic changes caused by each drug, which were found to rely on DNA, lipids, and proteins, acting as biomarkers of drug impact. The main changes were observed between the B-DNA native conformation and either Z-DNA or A-DNA, with a higher effect on lipids having been detected in the presence of cisplatin as compared to Pd2Spm. In turn, the Pd-agent showed a more significant impact on proteins.
Are strain-induced effects truly strain induced? A comprehensive study of strained LCMO thin films

We report results on strained La2∕3Ca1∕3MnO3 (LCMO) films that are able to distinguish between true strain effects and effects due simply to the reduced film thickness. Biaxially strained LCMO films were grown on SrTiO3, NdGaO3, and LaAlO3. The films on SrTiO3 and LaAlO3 are elastically strained and those on NdGaO3 are only slightly strained. We observe that both the saturation moment (Msat) and the Curie temperature (TC) are suppressed as the films become thinner, regardless of the strain. Thus, the decrease in Msat and TC is due to the two-dimensional nature of the films and not the strain.
Association of Depression, Poor Mental Health Status and Asthma Control Patterns in US Adults Using a Data-Reductive Latent Class Method

Objectives To explore the association between depression, poor mental health status, and asthma control patterns among US adults using a latent class analysis (LCA) approach. Methods We used data from 10,337 adults aged 18 years and above from the 2016 Behavioral Risk Factor Surveillance System (BRFSS) Asthma Call-back Survey. Data-reductive LCA was used to derive asthma control patterns in the population using class variables indicative of asthma control. Besides univariate analysis, adjusted and unadjusted logistic regression models were used to examine the association of depression and poor mental health on the derived asthma control patterns. Results About 27.8% of adults aged <55 reported depression, while 27.3% aged ≥55 years were depressed. The latent class prevalence of asthma control patterns was 42.8%, 31.1%, and 26.1%, corresponding to good, fair, and poor asthma control patterns, respectively. In adults aged <55 years, odds of depression (OR=1.52, 95% CI=1.27-1.82) and poor mental health (OR=1.58, 95% CI=1.27-1.96) were higher in the poor asthma control group compared to the good asthma control group. Odds for depression (OR=1.28, 95% CI=1.06-1.53) were also higher in the moderate asthma control group compared to the good asthma control group. Among those aged ≥55 years, depression odds (OR=1.57, 95% CI=1.31-1.87) were higher in only the poor asthma control group. Conclusions These findings may have public health implications. Detecting, screening, and treating depression and mental health disorders may help improve asthma control in people with asthma.
Dielectric constant of dipolar hard sphere mixtures

The dielectric constant of dipolar hard sphere mixtures is calculated from the analytic solution of the mean spherical approximation (MSA) and using Monte Carlo simulation. The MSA is solved using the factorization technique pioneered by Wertheim and Baxter and extended to nonspherical interactions by Blum. The simulations are performed using the Ewald technique to take into account the long‐ranged dipolar interactions. The simulation results are compared to those obtained from the MSA as well as a modified MSA and a continuum theory due to Looyenga.
When Hierarchical Federated Learning Meets Stochastic Game: Toward an Intelligent UAV Charging in Urban Prosumers

Unmanned aerial vehicles (UAVs) nowadays are developing rapidly for various applications such as UAV taxis and delivery drones. However, the limited battery energy restricts the flight distance of the UAVs. Thus, urban prosumers equipped with drone recharge stations are introduced to provide charging services for the UAVs. In this article, first, a day-ahead energy scheduling problem for UAV charging-enabled urban prosumers is studied, where the objective is to maximize the overall energy satisfaction of the prosumers with ensuring the Quality of Service (QoS) of the charged UAVs. Specifically, to deal with the considered problem, we decompose it into two stages: 1) the day-ahead energy requirement data prediction stage and 2) energy scheduling stage per prosumer. Thus, second, a joint method based on hierarchical federated learning (HFL) on long short-term memory (LSTM) architecture (HFL-LSTM) and stochastic game-based multi-agent double deep $Q$ -learning (MADDQN) with community agent-independent approach is proposed. In particular, the HFL-LSTM approach is leveraged to forecast each prosumer’s energy requirement data without centralized collecting local prosumers’ data such that to protect data privacy. Then, the stochastic game is adopted to analyze the formulated problem, aiming to find the Nash equilibrium (NE) strategy. Afterward, MADDQN with a community agent-independent method is utilized to achieve the best energy scheduling strategy per prosumer. Finally, the experimental results demonstrate the superiority of the proposed joint method that can achieve the lowest mean squared error with the value of 0.0152 and the highest energy satisfaction $(36388)$ achieved by the NE policy compared with the benchmarks.
INFLUENCE OF BOUNDARY CONDITIONS UNCERTAINTIES ON THE SIMULATION OF VENTILATED ENCLOSURES

The aim of this study is the assessment of the effect of input data uncertainties on the predictions achieved for a ventilated room by means of a computational fluid dynamics (CFD) technique. We first describe the characteristics of the model (experimental setup and numerical approach). This is followed by a review of sensitivity and uncertainty analysis methods in order to choose the most appropriate one. Taking into account the numerical model particularities, a differentiation analysis with finite differences is applied. The methodology is based on an automatic generation of the perturbation size imposed on the inputs. Experimental-numerical confrontations concerning the uncertainty domains are given for air mean velocity and temperature within the enclosure, as well as for room wall heat transfer calculations.
Oscillation theory for indefinite Sturm-Liouville problems with eigenparameter-dependent boundary conditions

In previous papers we have studied oscillation properties of Sturm–Liouville problems (−Py′)′ + qy = λry, with λ-dependent boundary conditions, under various ‘definiteness’ conditions. Here we present a new, unified, approach which also covers cases previously untreated, e.g. of semidefinite weight, and also the fully indefinite problem.
Governance Quality and Trade Performance in Sub-Saharan Africa

In this study, nexuses between governance and trade performance in terms of natural resource rents are assessed in 44 Sub‐Saharan African countries. The empirical evidence is based on Tobit regressions. The findings show that political governance (entailing “voice and accountability” and political stability) and institutional governance (consisting of the rule of law and corruption control) have a negative effect on trade performance. The findings are consistent with the perspective that resource rents are linked to inefficiencies in governance which are further detrimental to trade performance within the remit of natural resource rents on the one hand and, on the other, the premise of the prevailing weak institutions in the region less likely to boost trade performance.