Miracle-dz/UniFAR-FTUs huggingface dataset:
Comparison of wax ball centric registration technique with Gothic arch tracing: A clinical study

Background: Wax-ball centric relation technique is a novel, fast, dentist and patient friendly method of registration of centric position during establishment of jaw relation. Objective: To compare Wax Ball centric registration technique with Gothic arch tracing and record the deviations in recording Wax Ball centric registration technique compared to Gothic arch tracing. Materials and Methods: In a Clinical setting, comparative clinical Trial was conducted among a random sample of 20 elderly patients aged 30-60 years old, centric relation was recorded and compared using Wax Ball and Gothic arch tracing methods. The deviations observed with Wax ball technique compared to Gothic arch tracing method were recorded. Cohen’s Kappa test was applied to test the level of agreement between the techniques. Results: Out of the total 20 recordings of wax ball technique, 10 recordings showed deviations (Anterior -3, Posterior-7). The mean deviation was 0.6±0.5mm (Range 0-2mm). Mean anterior deviation was 1.16±0.7mm and mean posterior deviation was 0.92±0.34mm. There was fair agreement between the two methods. (66.66%-agreement, Cohen’s Kappa value=0.39). Conclusion: Wax-ball centric relation technique could be a useful, fast and user-friendly method to record centric position.
High Performance Reconstruction Framework for Straight Ray Tomography

We develop a high-performance scheme to reconstruct straight-ray tomographic scans. We preserve the quality of the state-of-the-art schemes typically found in traditional computed tomography but reduce the computational cost substantially. Our approach is based on 1) a rigorous discretization of the forward model using a generalized sampling scheme; 2) a variational formulation of the reconstruction problem; and 3) iterative reconstruction algorithms that use the alternating-direction method of multipliers. To improve the quality of the reconstruction, we take advantage of total-variation regularization and its higher-order variants. In addition, the prior information on the support and the positivity of the refractive index are both considered, which yields significant improvements. The two challenging applications to which we apply the methods of our framework are grating-based \mbox{x-ray} imaging (GI) and single-particle analysis (SPA). In the context of micro-resolution GI, three complementary characteristics are measured: the conventional absorption contrast, the differential phase contrast, and the small-angle scattering contrast. While these three measurements provide powerful insights on biological samples, up to now they were calling for a large-dose deposition which potentially was harming the specimens ({\textit{e.g.}}, in small-rodent scanners). As it turns out, we are able to preserve the image quality of filtered back-projection-type methods despite the fewer acquisition angles and the lower signal-to-noise ratio implied by a reduction in the total dose of {\textit{in-vivo}} grating interferometry. To achieve this, we first apply our reconstruction framework to differential phase-contrast imaging (DPCI). We then add Jacobian-type regularization to simultaneously reconstruct phase and absorption. The experimental results confirm the power of our method. This is a crucial step toward the deployment of DPCI in medicine and biology. Our algorithms have been implemented in the TOMCAT laboratory of the Paul Scherrer Institute. In the context of near-atomic-resolution SPA, we need to cope with hundreds or thousands of noisy projections of macromolecules onto different micrographs. Moreover, each projection has an unknown orientation and is blurred by some space-dependent point-spread function of the microscope. Consequently, the determination of the structure of a macromolecule involves not only a reconstruction task, but also the deconvolution of each projection image. We formulate this problem as a constrained regularized reconstruction. We are able to directly include the contrast transfer function in the system matrix without any extra computational cost. The experimental results suggest that our approach brings a significant improvement in the quality of the reconstruction. Our framework also provides an important step toward the application of SPA for the {\textit{de novo}} generation of macromolecular models. The corresponding algorithms have been implemented in Xmipp.
Frequency and clinical features of deficient mismatch repair in ovarian clear cell and endometrioid carcinoma

Objective To clarify the frequency of deficient mismatch repair (dMMR) in Japanese ovarian cancer patients, we examined microsatellite instability (MSI) status and immunohistochemistry (IHC) subtypes, including endometrioid carcinoma (EMC), clear cell carcinoma (CCC), or a mixture of both (Mix). Methods We registered 390 patients who were diagnosed with EMC/CCC/Mix between 2006 and 2015 and treated at seven participating facilities. For 339 patients confirmed eligible by the Central Pathological Review Board, MSI, IHC, and MutL homolog 1 methylation analyses were conducted. The tissues of patients with Lynch syndrome (LS)-related cancer histories, such as colorectal and endometrial cancer, were also investigated. Results MSI-high (MSI-H) status was observed in 2/217 CCC (0.9%), 10/115 EMC (8.7%), and 1/4 Mix (25%). Additionally, loss of MMR protein expression (LoE-MMR) was observed in 5/219 (2.3%), 16/115 (14.0%), and 1/4 (25%) patients with CCC, EMC, and Mix, respectively. Both MSI-H and LoE-MMR were found significantly more often in EMC (p<0.001). The median (range) ages of patients with MMR expression and LoE-MMR were 54 (30–90) and 46 (22–76) (p=0.002), respectively. In the multivariate analysis, advanced stage and histological type were identified as prognostic factors. Conclusion The dMMR rate for EMC/CCC was similar to that reported in Western countries. In Japan, it is assumed that the dMMR frequency is higher because of the increased proportion of CCC.
Circular economy in the Australian AEC industry: investigation of barriers and enablers

ABSTRACT The architecture, engineering and construction (AEC) industry has a reputation for low resource efficiency worldwide. Policymakers are exploring various avenues to address the issue, with one option being a shift toward a circular economy (CE). However, first one must identify how the relevant stakeholders perceive the concept. Hence, this study aimed to elicit stakeholders’ perceptions about CE and identify the main barriers and enablers affecting its adoption in the Australian context. A total of 132 respondents representing various stakeholder groups were surveyed. The findings revealed that only participants’ awareness of CE has a meaningful link with adoption; and this has a statistically significant association with major CE adoption indicators (i.e. adoption, willingness to apply, level of agreement on considering CE as business ethics and that CE is beneficial). The top three barriers were a: ‘lack of incentives’; ‘lack of specific regulations’; and a ‘lack of knowledge’. The three top enablers were reported to be ‘R&D of enabling technologies’, ‘educate project stakeholders’ and ‘provide evidence for the CE added value’. This paper could inform policy development activities in the Australian context and provides the foundation for a roadmap to a CE within the national AEC industry.
Consumer Satisfaction, Consumer-Brand Identification, and Repurchase Intention

This study proposes whether consumers will be loyal to a product with a brand that they have just bought and tried by knowing their repurchase intention. This study unfolds consumer satisfaction and consumer brand identification as the factors which can influence repurchase intention. A total of 177 samples were used. Path analysis in WarpPLS was used to examine the proposed hypotheses. The results showed a positive relationship influence of consumer satisfaction on repurchase intention. The results also showed a positive consumer-brand identification on repurchase intention. However, consumer-brand identification failed to moderate the relationship between customer satisfaction and repurchase intention.
Stem-nesting Hymenoptera in Irish farmland: empirical evaluation of artificial trap nests as tools for fundamental research and pollinator conservation

Insect pollinators are suffering global declines, necessitating the evaluation and development of methods for long-term monitoring and applied field research. Accordingly, this study evaluated the use of trap nests (“bee hotels”) as tools for investigating the ecology of cavity nesting Hymenoptera within Irish agricultural landscapes. Three trap nests consisting of 110 mm diameter plastic pipe containing 100 cardboard nest tubes of varying diameter were placed at eight apple orchards and eight oilseed rape sites and left in the field for five months. Sealed nest tubes occurred at 15 of the 16 sites, and in 77% of the 48 nests. However, only 7% of the 4800 individual nest tubes were sealed, and only 4% produced cavity-nesting Hymenoptera. Three cavity nesting bee species (Hylaeus communis, Osmia bicornis, Megachile versicolor) and two solitary wasp species (Ancistrocerus trifasciatus, A. parietinus) emerged from nest tubes. There were significant differences among species in terms of emergence date and the diameter of nest tubes from which they emerged, the latter allowing the calculation of niche width and niche overlap, and informing choice of tube size in future studies/conservation efforts. Trap nests, therefore, offer a valuable tool for fundamental ecological research and a model system for investigating interactions between stem-nesting species within their wider ecological networks. The ability of trap nests to actually increase farmland pollinator abundance and diversity as part of agri-environment schemes requires additional investigation. However, used in sufficient numbers, these trap nests provide valuable biogeographical data for cavity nesting Hymenoptera and offer a viable means for long term monitoring of these species in Irish farmland.
Wildfire does not affect spore abundance, species richness, and inoculum potential of arbuscular mycorrhizal fungi (Glomeromycota) in ferruginous Canga ecosystems

Canga ecosystems develop over superficial iron crusts with shallow and nutrient-poor soils. Under these conditions, arbuscular mycorrhizal fungi (AMF) play an important role in helping plants to overcome abiotic and biotic stresses. Canga can suffer periodic burning and yet it is unknown what the impacts of fire are to AMF communities. We aimed to compare AMF in Canga areas affected by burning (BC) with those with no previous history of burning (NC). We compared AMF species composition, spore numbers, species richness, and mycorrhizal inoculum potential. The total number of spores, AMF species richness and mycorrhizal colonization measured in the infectivity bioassay were not significantly different between areas. A total of 23 species in 10 genera were recovered, with most species belonging to Gigasporaceae and Acaulosporaceae. BC and NC shared 52 % of AMF species. Gigaspora albida, Gigaspora gigantea, and Dentiscutata heterogama sporulated exclusively in trap cultures. We concluded that AMF spore communities were not affected by burning in Canga soils as measured by spore abundance, species richness and infectivity. Our data contribute to the inventory of soil biodiversity associated with Canga, a high biodiverse and threatened Brazilian ecosystem.
Parental Efficacy in Managing Smartphone Use of Adolescents with Attention-Deficit/Hyperactivity Disorder: Parental and Adolescent Related Factors

Parental management has an important role in preventing problematic smartphone use among adolescents with attention-deficit/hyperactivity disorder (ADHD). This study aimed to examine the parental factors (e.g., demographics, depressive symptoms and parenting styles) and adolescent factors (e.g., demographics, ADHD and oppositional defiant disorder [ODD] symptoms, and problematic smartphone use) related to parental efficacy in managing adolescent smartphone use (PEMASU) among 237 parents of adolescents with ADHD. PEMASU was measured by the Parental Smartphone Use Management Scale. Parental depressive symptoms and parenting styles (parental affection/care and overprotection) were measured by the Center for Epidemiologic Studies—Depression Scale and Parental Bonding Instrument, respectively. Adolescent ADHD and ODD symptoms and problematic smartphone use were measured by the Swanson, Nolan, and Pelham, version IV scale and Problematic Smartphone Use Questionnaire, respectively. Three models of hierarchical linear regression were performed to examine the parental and adolescent factors related to PEMASU. The results indicated that adolescent older age and more severe ODD symptoms and problematic smartphone use were significantly associated with lower PEMASU, whereas greater parental affection/care was significantly associated with higher PEMASU. This study demonstrated that both parental and adolescent factors contribute to PEMASU among parents of adolescents with ADHD. Intervention programs aiming to enhancing PEMASU need to take these related factors into consideration.
Monensin supplementation during late gestation of beef cows alters maternal plasma concentrations of insulin-like growth factors 1 and 2 and enhances offspring preweaning growth

Abstract This study evaluated the effects of maternal prepartum supplementation of dried distillers grains (DDG), with or without monensin addition, on maternal performance and physiology and offspring preweaning growth. On day 0 (approximately 197 ± 4 d prepartum), 150 multiparous, Brangus crossbred beef cows were ranked by their initial body weight (BW; 524 ± 51 kg) and body condition score (BCS; 5.0 ± 0.63), and then randomly assigned into one of 15 bahiagrass (Paspalum notatum) pastures (10 cows and 8.1 ha/pasture). Maternal treatments were randomly assigned to pastures (5 pastures/treatment) and consisted of no prepartum supplementation of DDG (NOSUP) or supplementation of DDG at 1 kg/cow/d (dry matter basis; DM) added with 0 mg (SUP) or 200 mg/d of monensin (SUPMO) from days 0 to 77. Effects of maternal treatment and maternal treatment × day of the study were not detected (P ≥ 0.63) for any forage data. Cow BCS on day 35 and near calving (day 77) did not differ (P ≥ 0.19) between SUP and SUPMO cows but both groups had greater (P ≤ 0.001) BCS compared with NOSUP cows. Cow BCS at the start of the breeding season (day 142) and on day 168 were the greatest (P < 0.0001) for SUPMO cows, least for NOSUP cows, and intermediate (P ≤ 0.02) for SUP cows. Maternal plasma concentrations of glucose did not differ (P ≥ 0.25) among treatments. Plasma concentrations of insulin-like growth factor 1 (IGF-1) on day 77 were the least for NOSUP cows (P ≤ 0.05) and did not differ (P = 0.66) between SUP and SUPMO cows, whereas plasma concentrations of IGF-2 on days 35 and 77 were greatest (P ≤ 0.05) for SUPMO cows and did not differ (P ≥ 0.60) between NOSUP and SUP cows. Birth BW of first offspring did not differ (P = 0.77) between SUP and SUPMO calves but NOSUP calves were lighter at birth (P ≤ 0.05) compared with SUP and SUPMO calves. Percentage of cows pregnant with a second offspring did not differ (P = 0.72) between SUP and SUPMO cows and were the least for NOSUP cows (P ≤ 0.05). First offspring BW at weaning (day 325) was greatest (P ≤ 0.05) for SUPMO calves, least for NOSUP calves, and intermediate for SUP calves. Therefore, adding monensin into prepartum DDG supplements for Bos indicus-influenced beef cows did not increase cow prepartum BCS but led to greatest offspring preweaning growth, likely by modulating maternal plasma concentrations of IGF-1 and IGF-2 during gestation.
Increased LRG1 Levels in Overweight and Obese Adolescents and Its Association with Obesity Markers, Including Leptin, Chemerin, and High Sensitivity C-Reactive Protein

Leucine-rich α-2 glycoprotein1 (LRG1) is a member of the leucine-rich repeat (LRR) family that is implicated in multiple diseases, including cancer, aging, and heart failure, as well as diabetes and obesity. LRG1 plays a key role in diet-induced hepatosteatosis and insulin resistance by mediating the crosstalk between adipocytes and hepatocytes. LRG1 also promotes hepatosteatosis by upregulating de novo lipogenesis in the liver and suppressing fatty acid β-oxidation. In this study, we investigated the association of LRG1 with obesity markers, including leptin and other adipokines in adolescents (11–14 years; n = 425). BMI-for-age classification based on WHO growth charts was used to define obesity. Plasma LRG1 was measured by ELISA, while other markers were measured by multiplexing assay. Median (IQR) of LRG1 levels was higher in obese (30 (25, 38) µg/mL) and overweight (30 (24, 39) µg/mL) adolescents, compared to normal-weight participants (27 (22, 35) µg/mL). The highest tertile of LRG1 had an OR [95% CI] of 2.55 [1.44, 4.53] for obesity. LRG1 was positively correlated to plasma levels of high sensitivity c-reactive protein (HsCRP) (ρ = 0.2), leptin (ρ = 0.2), and chemerin (ρ = 0.24) with p < 0.001. Additionally, it was positively associated with plasma level of IL6 (ρ = 0.17) and IL10 (ρ = 0.14) but not TNF-α. In conclusion, LRG1 levels are increased in obese adolescents and are associated with increased levels of adipogenic markers. These results suggest the usefulness of LRG1 as an early biomarker for obesity and its related pathologies in adolescents.
Characteristics and Clinical Ocular Manifestations in Patients with Acute Corneal Graft Rejection after Receiving the COVID-19 Vaccine: A Systematic Review

This study aimed to determine the characteristics and clinical ocular manifestations of acute corneal graft rejection after coronavirus disease 2019 (COVID-19) vaccination. We conducted an online search of the PubMed and EMBASE databases. Data on recipients’ characteristics, corneal transplantation types, interval between vaccination and allograft rejection, clinical manifestations, and graft rejection medication were extracted. Thirteen articles on 21 patients (23 eyes) with acute corneal graft rejection after COVID-19 vaccination, published between April and December 2021, were included. The median (interquartile range) age at the onset of rejection was 68 (27–83) years. Types of transplantation included penetrating keratoplasty (12 eyes), Descemet membrane endothelial keratoplasty (six eyes), Descemet stripping automated endothelial keratoplasty (four eyes), and living-related conjunctival-limbal allograft (one eye). The interval between vaccination and rejection ranged from 1 day to 6 weeks. Corneal edema was the leading clinical manifestation (20 eyes), followed by keratic precipitates (14 eyes) and conjunctival or ciliary injection (14 eyes). Medications included frequently applied topical corticosteroids (12 eyes), followed by a combination of topical and oral corticosteroids (four eyes). In addition, the clinical characteristics of corneal allograft rejection after COVID-19 vaccination were identified. Corneal transplant recipients may require further vaccination, necessitating appropriate management and treatment.
Soft Tissue and Biomolecular Preservation in Vertebrate Fossils from Glauconitic, Shallow Marine Sediments of the Hornerstown Formation, Edelman Fossil Park, New Jersey

Simple Summary Original organics and soft tissues are known to persist in the fossil record. To date, these discoveries derive from a limited number of ancient environments, (e.g., rivers, floodplains), and fossils from rarer environments remain largely unexplored. We studied Cretaceous–Paleogene fossils from a peculiar marine environment (glauconitic greensand) from Jean and Ric Edelman Fossil Park in Mantua Township, NJ. Twelve samples were demineralized in acid to remove the mineral component of bone. This treatment frequently yielded products that are visually consistent with bone cells, blood vessels, and bone matrix from modern animals. Fossil specimens that are dark in color exhibit excellent microscopic bone preservation and yielded a greater recovery of original soft tissues, whereas light-colored specimens exhibit poor microscopic preservation and yielded few to no soft tissues. Additionally, a well-preserved femur of a marine crocodilian was found to retain original bone protein by reactions with antibodies. Our results: (1) corroborate previous findings that original soft tissue and proteins can be recovered from fossils preserved in marine environments, and (2) expand the range of ancient environments documented to preserve original organics and soft tissues. This broadens the suite of fossils that may be fruitful to examine in future paleomolecular studies. Abstract Endogenous biomolecules and soft tissues are known to persist in the fossil record. To date, these discoveries derive from a limited number of preservational environments, (e.g., fluvial channels and floodplains), and fossils from less common depositional environments have been largely unexplored. We conducted paleomolecular analyses of shallow marine vertebrate fossils from the Cretaceous–Paleogene Hornerstown Formation, an 80–90% glauconitic greensand from Jean and Ric Edelman Fossil Park in Mantua Township, NJ. Twelve samples were demineralized and found to yield products morphologically consistent with vertebrate osteocytes, blood vessels, and bone matrix. Specimens from these deposits that are dark in color exhibit excellent histological preservation and yielded a greater recovery of cells and soft tissues, whereas lighter-colored specimens exhibit poor histology and few to no cells/soft tissues. Additionally, a well-preserved femur of the marine crocodilian Thoracosaurus was found to have retained endogenous collagen I by immunofluorescence and enzyme-linked immunosorbent assays. Our results thus not only corroborate previous findings that soft tissue and biomolecular recovery from fossils preserved in marine environments are possible but also expand the range of depositional environments documented to preserve endogenous biomolecules, thus broadening the suite of geologic strata that may be fruitful to examine in future paleomolecular studies.
Weak nearly uniform soothness and worth property of fidirect sums of Banach spaces

We shall characterize the weak nearly uniform smoothness of the ψ-direct sum X⊕ψY of Banach spaces X and Y . The Schur and WORTH properties will be also characterized. As a consequence we shall see in the `∞-sums of Banach spaces there are many examples of Banach spaces with the fixed point property which are not uniformly non-square. 2000 Mathematics Subject Classification: 46B20, 46B99.
Measuring the Economic Value of the Negative Externality of Livestock Malodor in South Korea

The South Korean livestock industry has increased in scale and production, generating positive impacts on the national economy. However, livestock externalities, primarily malodor, have subsequently led to increased conflicts between producers and affected communities. This study estimated Korean households’ willingness-to-pay (WTP) for government subsidies to help address livestock malodor using a contingent valuation method (CVM) derived from a double-bounded dichotomous choice model. The annual average household WTP was estimated at 29,206 Korean won (KRW) (USD 25). This was slightly higher than the respondents’ self-reported average amount of KRW 25,457 (USD 22). The estimated economic value nationally is KRW 628 billion (USD 546 million) annually, for a total of KRW 3.14 trillion (USD 2.73 billion) over a proposed five-year period. The public’s estimated WTP can be leveraged to improve livestock management practices, more efficient waste disposal techniques, and improved husbandry methods to address conflicts between producers and surrounding communities.