Miracle-dz/UniFAR-FTUs huggingface dataset:
Effect of Massage Before or After Exercise on Delayed-onset Muscle Soreness in a Rat Model

Background. Delayed-onset muscle soreness (DOMS), also known as tenderness of touch, refers to the pain caused by muscle mechanical stimulation, such as contraction and stretching. Chinese massage has been widely used in the treatment of sports fatigue and sports injury, but there is controversy in the efficacy. In this experiment, we established DOMS model in rats to observe the prevention and treatment effect of massage, to find the best time for intervention, and to provide scientific basis for the prevention and treatment of exercise fatigue.Methods. 130 male SD(sprague-dawley, SD) healthy rats were randomly divided into blank group, control group and massage group. Except for blank group, the other rats received DOMS model. Professionals applied kneading and twisting methods on both lower limbs of rats. The expression of IL-2, IL-6 and IL-8 in skeletal muscle of rats were determined by western blot, PCR and ELISA, and the content of serum creatine kinase was determined by ELISA. In addition, we measured the concentration of Ca2+, Ca2+-ATPase in mitochondria of skeletal muscle. The changes of skeletal muscle structure were observed by scanning electron microscopy.Result. After massage, the expression of IL-2, IL-6, IL-8 and CK decreased compared with control group (P < 0.01), the expression of IL-2, IL-6 and IL-8 in post massage group was lower than that in front massage group (P < 0.01), and the content of CK in front massage group was lower than that in post massage group(P < 0.01). The content of Ca2+ in front massage 24, 48 and 72h group was lower than that in post massage (P < 0.01), the concentration of Ca2+-ATPase in front massage 24h and 72h group was lower than that in post massage group (P < 0.05). Conclusion. Massage can prevent the injury of muscle and reduce the inflammatory reaction of muscle after exercise. It can also improve the activity of Ca2+-ATPase, enhance the transport of Ca2+ by mitochondria and protect the skeletal muscle.
Photo-driven CO2 Reduction to Hydrocarbons: Carbon Flux and Energy Transforming by Marine Microbial Community

Background: Microbial activities play a crucial role in the carbon and energy cycle of the ocean. Microbial communities in the MCP has been proposed the function of transforming carbon, yet the potential for direct CO 2 reduction to the organic carbon is rarely considered in the carbon cycle and energy transforming. Results: Here we showed a naturally inherent photo-driven bioprocess of CO 2 reduction producing C 1 -C 6 alkanes/alkenes by the marine microbial community with CO 2 consumption rate of 100.87 uM day -1 . Upon the metabolite profiles and metagenomic sequencing analysis, we revealed the mechanism of CO 2 conversion to hydrocarbons that CO 2 fixation was dominantly completed with the Calvin-Benson-Bassham cycle, tricarboxylic acid cycle, and Wood-Ljungdahl cycle, while nitrogenases, aldehyde decarbonylase and carboxylic acid reductase played the crucial roles on the hydrocarbon formations. As these insights, the pathway of CO 2 to hydrocarbons was proposed. Isolated microorganisms from the enriched community, including Pseudomonas sp. , Serratia sp. , Candidatus sp. , Clostridium sp. , Enterococcus sp . , Salmonella sp. , Rhodospirillum sp. , Thalassospira sp. , Thioclava sp. , Stenotrophomonas sp. and Desulfovibrio sp. , were tentatively integrated for validating the hypothesized process. Results exhibited that the improved performance of CO 2 reduction to hydrocarbons was achieved by this group. Conclusions: This study demonstrated a natural microbial CO 2 reduction process contributing to the carbon and energy cycle in the ocean, and could provide a microbial “CO 2 -hydrogenation process” or “fischer-tropsch process” for industrial application.
STUDENTS’ PERCEPTIONS OF TEACHERS’ WRITTEN CORRECTIVE FEEDBACK IN THE MALAYSIAN ESL CLASSROOM

Purpose – This study examined the types of written corrective feedback provided to ESL students in writing classes in Malaysian secondary schools, and their perceptions towards the provision of written corrective feedback in the Malaysian context. Methodology – A survey questionnaire was administered randomly among 720 Form Four students from 10 secondary schools in Penang. The questionnaire was based on a Likert scale and responses were analysed using descriptive statistics. Findings – Results showed that most learners benefited from and preferred direct feedback, and tended to focus on form such as grammar, paragraph organisation, content and clarity of ideas. Students preferred this form of feedback as they were able to understand errors more clearly. It was found that most students were unable to self-regulate their own errors; a majority could not locate their own errors and had become passive learners within the Malaysian schooling system. Significance – The study is significant to Malaysian secondary schools in its effects, depicting the many forms of corrective feedback available in the ESL context that can be employed in school besides the popularized direct feedback used within the syllabus.
Why do Italian psychology graduates dream of becoming psychotherapists?

The role of potential motivations for psychotherapy training is receiving growing attention in the context of psychotherapy research. The present study examines the entire decision-making process for undertaking psychotherapy training in Italian psychology graduates. This is a quali-quantitative study using mixed methods and recruiting from a convenience sample. An on-line questionnaire with open-ended questions about problem/ need recognition, information search, alternative evaluation, purchase, and post-purchase
RETURN SAHAM PERUSAHAAN SUBSEKTOR PROPERTI DAN REAL ESTATE DI INDONESIA: RASIO LIKUIDITAS, RASIO SOLVABILITAS, DEGREE OF LEVERAGE

<p class="Standard"><em>Keuntungan </em><em>dalam ber</em><em>investasi di pasar modal dapat dicerminkan melalui perolehan return atas saham yang dipilih. </em><em> </em><em>Saat ini, semakin banyak investor yang berminat berinvestasi di perusahaan propert</em><em>i</em><em>. </em><em>Bisnis properti sangat menjanjikan dikarenakan tingginya permintaan dari masyarakat dan harga jual properti yang memiliki kecenderungan selalu naik</em><em>. </em><em> </em><em>Penelitian ini </em><em>bertujuan untuk </em><em>menguji</em><em> </em><em>pengaruh rasio likuiditas, rasio solvabilitas</em><em>,</em><em> dan degree of leverage terhadap return saham. Penelitian ini menggunakan</em><em> sampel</em><em> data keuangan perusahaan yang bergerak </em><em>di</em><em> subsektor properti dan real estate yang terdaftar di BEI pada periode tahun 2012 s.d. </em><em>tahun </em><em>2019. </em><em> Hasil penelitian ini menunjukkan bahwa </em><em>solvabilitas berpengaruh positif terhadap return saham </em><em>sedangkan</em><em> likuiditas, operating leverage dan financial leverage tidak berpengaruh terhadap return saham perusahaan. </em></p>
Stress and Sleep Disturbances During a COVID-19 Lockdown April 2020

A COVID-19 related Stress Scale was developed for this study to address the specific stressors related to the pandemic lockdown experience. Based on a Survey Monkey study on 260 healthy individuals (18-82 years), the stress scale scores and its individual items were significantly correlated with scores on scales for health, media use, mood states including anxiety and depression, posttraumatic stress symptoms, fatigue and sleep disturbances. Stepwise regression analysis suggested that depression, media use and fatigue scale scores contributed to 52% of the variance on the stress scale scores. In turn, the stress scale scores and items were significantly correlated with sleep disturbances, as were health, anxiety, depression, fatigue and PTSD symptoms. Stepwise regression analysis revealed that 52% of the variance on the sleep scale scores was explained by fatigue and posttraumatic stress scale scores. These data suggest that individuals experiencing COVID-19 lockdowns are experiencing psychological symptoms and lockdown-related stressors that are contributing to sleep disturbances that highlight the need for interventions during lockdowns. Stress and Sleep Disturbances During a COVID-19 Lockdown April 2020
Proteomic Analysis of CRISPR Cas 9 Mediated Mdig Deletion in Triple Negative Breast Cancer Cells

BackgroundWe have identified an environmentally inducible gene, mdig that predicted the overall survival in breast cancer patients. We showed that mdig regulated breast cancer cell growth, motility and invasion partially through DNA and histone methylation. However, we have lacked a comprehensive analysis of the proteomic profile of mdig in triple negative breast cancer cells. MethodsWe applied mass spectrometry to acquire global proteomic and post translational modification analysis for triple negative breast cancer cells MDA-MB-231 that had mdig deleted via CRISPR Cas 9 gene editing. Using label-free bottom up quantitative proteomics, we compared wildtype control (WT) and mdig knockout (KO) MDA-MB-231 cells and identified the proteins and pathways that are significantly altered with mdig deletion. The Ingenuity Pathway Analysis (IPA) platform was further used to explore the signaling pathway networks incorporating differentially expressed proteins. Results904 differentially expressed (p < 0.005) proteins were identified in MDA-MB-231 cells that had mdig deletion. Approximately 30 pathways and networks linked to the pathogenicity of breast cancer and populated by the differentially expressed proteins were either activated or inhibited. IPA established that the differentially expressed proteins have relevant biological actions in cell growth, motility and malignancy. This analysis provides a rich source of potential candidate therapeutic targets with potential prognostic significance in triple negative breast cancer. Data are available via ProteomeXchange with identifier PXD016688.Conclusions These data provide the first insight into protein expression patterns in breast cancer associated with a complete disruption of the mdig gene. Differentially expressed proteins between WT and KO MDA-MB-231 triple negative breast cancer cells provide substantial information regarding key proteins, biological process and pathways that are modulated by mdig and contribute to breast cancer tumorigenicity and invasiveness. Mdig modulated signaling pathways and hub molecules provide novel targets for the development of treatment strategies and breast cancer therapies.
To assess the knowledge of adolescents about the dietary behaviour & its consequences

Background: Adolescence represents a real opportunity to make a difference in lifelong patterns. There are 1.2 billion adolescents in the world, 85% of them live in developing countries. The adolescent population constitutes about 18 to 25% of the total population of the South East Asia Region. Objective: To assess the knowledge of Adolescents about the dietary behaviour & its consequences. Material and Methods: The present observational cross-sectional study was carried out in Department of Community Medicine, Santosh Medical College, Ghaziabad & Urban area of district Ghaziabad. The unit of the study was selected adolescent students studying in randomly selected schools of Ghaziabad city. Adolescents aged 10 to 19 years studying in the selected schools of urban Ghaziabad were included for the study. The period of study was from November 2011 to October 2012 Results: 253 (67.5%) male and 192 (51.2%) female had knowledge about healthy diet. about half of the female 193 (51.5%) preferred homemade food while about two-third 252 (67.2%) of boys preferred outside food. Males 162 (43.2%) ate junk food daily, 183 (48.8%) ate weekly and 30 (8.0%) ate occasionally while in females 108 (28.8%) ate junk food daily, 218 (58.1%) ate weekly and 49 (13.1%) ate occasionally. 270 (72.0%) male and 265 (70.7%) female had knowledge that consuming junk food regularly can harm health. 209 (55.7%) male and 224 (59.7%) female were encouraged from surrounding to eat outside or junk food. Conclusions: Considering the large no. of adolescents in our country, the study thus evokes an urgent need to stimulate an action to identify those at risk and those who need treatment and prevention of progression of the health risk behaviors, among the adolescents.
Platelet-to-lymphocyte ratio at 24h after thrombolysis is a prognostic marker in acute ischemic stroke patients

Background The changes in the platelet-to-lymphocyte ratio (PLR) before and after recombinant tissue plasminogen activator (rtPA) treatment and the time point at which the PLR is a potentially valuable prognostic predictor in patients wit ischemic stroke remain largely unknown. Therefore, the purpose of this study was to explore the characteristics of the PLR and evaluate their effects on clinical outcomes before and 24 h after rtPA treatment. Methods This study included 741 consecutive patients with acute ischemic stroke who underwent intravenous thrombolysis with rtPA. We collected data on demographics, vascular risk factors, medication history, and other clinical information pertaining to all patients. Specifically, blood samples for PLR measurement were collected on admission and 24 h after stroke. The outcome was assessed by using the Modified Rankin Scale (mRS) at 3 months and whether death occurred within 3 months or not. Univariate and multivariate logistic regression analysis was used to assess the association of the PLR with the risks of poor outcome (mRS>2) and death. An individualized prediction model was established to predict poor outcome. Results Of the 741 patients, 255 (34.4%) had poor outcome, and 43 (5.8%) died. The PLR significantly increased 24 h after rtPA in patients with poor outcome and death. Logistic analysis revealed that higher PLR 24 h after rtPA was independently associated with increased risks of poor outcome and death. However, the PLR on admission was not associated with the risks of poor outcome and death. The individualized prediction model for poor outcome based on the 24-h PLR exhibited favorable discrimination (areas under the curves of the training and validation groups: 0.743 and 0.729, respectively), calibration (P > 0.05), and clinical usefulness. Conclusions We found the PLR to be a variable that potentially predicts the risks of poor outcome and death in patients with acute ischemic stroke 24 h after rtPA; however, it cannot make the same prediction on admission.
Linking African and Western models through integration of trickster folktales in the application of Cognitive Behavior Therapy for depression

With independence in the 1950’s and 60’s, the number of African students in European and American universities increased significantly. At least 9.1% of all international students in the United States were Africans (Zikopoulos, 1997). Major re-entry challenges for Africans are how to effectively address the differences between western psychological theories and techniques and the African belief systems, ideas about causation, illness behavior and therapeutic expectations (Nzewi, 1989,1992). This is the central question in the dialectical discourse on cultural relativism and universalism. If there is primacy of the human universals (the biological æYXO§O°IA, 2009, 16 (2) ◆ 146-163 PSYCHOLOGY, 2009, 16 (2) ◆ 146-163
Sources and Severity of Stress in Various Domains among First Year Medical Students and its Relationship with their Academic Performance: A Cross Sectional Study

Background: First year medical students are the most vulnerable group to experience stress in their newenvironment in the field of medicine. The present study evaluated perceived stress among them along withits correlation with academic performance.Method: An Indian adaptation of the Medical Student Stressor Questionnaire (MSSQ) was used to determinethe effect of stress on the academic performance of students. Responses were correlated with their respective1st professional exam marks.Results: Stress due to examinations was reported by 24.5% students and due to excess syllabus by 33%. Some students (11.8%) experienced severe stress due to relationship issues, due to unjustified gradingprocess (10.4%) and health issues. Females had more academic and group activity related stress as comparedto males. The students who participated in sports or cultural societies had higher Drive and Desire relatedstress levels in contrast to the non-participants. The interpersonal & intrapersonal relatedstress (IRS score)of students was negatively correlated with their academic performance. The increased stress among femaleparticipants was related to an improved academic performance in them.Conclusions: Too much stress negatively interfered with student’s preparation, concentration andperformance while positive stress helped student achieve peak performance.
Mortality trends in a Cohort of Canadian Psoriatic Arthritis Patients

Methods: We reviewed retrospectively the charts of psoriatic arthritis patients who died from 1995-2010.We included 13 deceased patients with a psoriatic arthritis di-agnosis and compared them with 140 patients living with psoriatic arthritis that at-tend the same clinic. The population was derived from a single academic rheumatol-ogist’s practice in St. John’s, Newfoundland, Canada. Patients are seen at six-month intervals with a history and physical exam performed at each visit. Laboratory data was collected at each visit. Diagnosis of psoriatic arthritis is based on the CASPAR Classifcation and Diagnostic Criteria for Psoriatic Arthritis. Results: The mean age of the 13 deceased patients was 62.9 years. Of these, 38.5% were female and 85.7% had an erythrocyte sedimentation rate greater than 15 mm/hour vs. 36.4% of patients living with psoriatic arthritis. Of deceased patients, 16%had dystrophic nail changes of vs. 59.6% of living patients. Health Assessment Questionnaire was found to show a signifcantly greater loss in function in deceasedpatients. (1.39 vs. 0.70, p= 0.002). Almost half of the deceased patients had used Prednisone (46.2%) as opposed to 11.2% of living patients. Conclusions: We realize that this study employs a small sample size. Increased ESR and Health Assessment Questionnaire score were found to be associated with mor-tality in psoriatic arthritis patients. Dystrophic nail changes were found to be pro-tective for psoriatic arthritis patients.
Physiochemical properties of n-n heterostructured TiO2/Mo-TiO2 composites and their photocatalytic degradation of gaseous toluene

Abstract The composite TiO2/Mo-TiO2 were prepared by a modified sol-gel method. The prepared catalysts were characterized by X-ray diffraction, BET analysis, SEM, X-ray photoelectron spectroscopy, and UV–vis diffused reflectance spectroscopy techniques. The structural characterization results demonstrated that Mo was successfully doped into the TiO2 lattice and caused slight changes in the physiochemical properties. The UV–vis DRS showed a red shift of the adsorption edge to the visible region. The photocatalytic decomposition efficiencies of the catalysts were examined with toluene as a typical VOC in a continuous flow reactor. The photocatalytic activity of the n-n heterogeneous TiO2/Mo-TiO2 was greater than that of pure TiO2 and Mo-TiO2, and the catalyst containing a Mo/Ti mole ratio of 2.5% exhibited optimum photocatalytic properties. In general, a relative humidity of 35%, a higher oxygen content, a lower initial toluene concentration, and a higher UV intensity were beneficial for toluene decomposition.
Cryptoparties: empowerment in internet security

: Cryptoparties (CPs) are a global movement of forums where citizens can come to learn how to improve their digital privacy and security. The present paper is one of the few empirical studies on CPs and is based on participant observation of three CPs. I demonstrate that the organisers of CPs strive for an egalitarian space for teaching and learning. Even though this goal is not always achieved, CPs might still serve as an example of citizen education in a technological society where every citizen needs to deal with complex technological issues. In addition, this paper contributes to the emerging debate on ‘doing internet governance’, broadening our focus to include user-based and decentred practices. I argue for the political relevance of CPs showing how they enact decentred threat-scenarios to a non-expert public.
Fast high-resolution nanoDMA measurements with a 25 ms response time electrometer

ABSTRACT Two fast electrometer circuits (1011 and 1012 V/A) are installed in a Faraday cage having a relatively small residence time. Removing readily distinguishable occasional spikes, the root mean square (r.m.s.) noise level at 1012 V/A is 0.11 fA when acquiring data at 1 Hz. This value is close to the expected thermal resistor noise at room temperature (0.09 mV). Both electrometers exhibit a 20 ms flow-related delay, followed by respective half-height rise-times of ∼4 and 25 ms. Fast high-resolution mobility spectra in the 1–2 nm size range are acquired with electrosprayed tetraheptylammonium ions by combining these electrometers with a high-speed DMA. At 1012 V/A, there is no ion mobility peak distortion when acquiring data with discrete voltage steps and dwelling 100 ms at each voltage. With the 1011 V/A electrometer, the DMA voltage VDMA is continuously swept up and down over 600 V in a triangular wave, at up to 1200 V/s. A shift ΔVDMA in the peak center is apparent, with little peak shape distortion. ΔVDMA is symmetric with respect to up or down sweep, and linear with sweep frequency, corresponding approximately to a pure delay Δt = 25 ms. This peak displacement may be offset by adding the correction ΔVDMA = Δt (dVDMA/dt) to the measured peak voltage. Extrapolating the measurements made here over a mobility range Zmax/Zmin of 4 to a much wider mobility range of 300 typical of aerosol studies, we conclude that almost undistorted high-resolution mobility spectra may be acquired in 1.3 s. Copyright © 2017 American Association for Aerosol Research
Time spent in referral process and its determinants among clients of maternal and child health service in Jimma zone, Ethiopia, 2020; A cross-sectional study.

Background The time spent between referring and receiving health facilities is an important determinant of the outcome of the referred patients/clients especially among women in low income countries due to poor access to early and appropriate referrals. Thus, the aim of this study is to assess the average time spent between referring and service utilization at receiving health facility.Methods A cross-sectional study was employed by using time and motion approach. Structured questionnaire and observation checklist were used for collecting data. SPSS 21 version was used for data analysis and binary and multivariable logistic regression analysis was carried out to identify a variable which has a significant association on the basis of OR, 95% CI and a P value of less than 0.05. Result A total of 266 women were participated in the study with the mean age of the study population is 24.65(± 5.03) years. Majority 223(83.8%) of the participants came for maternal health services and more than half 143(53.8%) of the respondents were self-referrals. Amongst the referred cases the main reason for the referral was for further evaluation and management. Women spent a maximum of 540 minutes on the way to arrive at receiving health facility. Residence and distance were the predictor variables for average time spent. More than two fifth of the women wait more than three hours to get the service at receiving health facility. Residence and distance were the determinant variables for average time spent.Conclusion In general, women wait a maximum of one and half hours to contact health care providers for assessment and more than two fifth of the women wait more than three hours to get the service at receiving health facility. Giving due emphasis to referral system as an integral part of maternal health was essential.