Miracle-dz/UniFAR-FTUs huggingface dataset:
Review of “Impact of Holuhraun volcano aerosols on clouds in cloud-system resolving simulations” by to Atmospheric Chemistry and

This study performed sensitivity experiments for a region around the North Atlantic to investigate the effects of volcanic smoke aerosols as cloud condensation nuclei (CCN) associated to the eruption in Holuhraun on the cloud properties in the volcanic smoke trails. A scientific goal is to investigate how liquid water path (LWP) and cloud fraction change in response to increase in CCN and subsequently cloud droplet number (Nd) in the volcanic plumes. Regional cloud-resolving simulations with approximately 2.5 km grid spacings were conducted for a week when emission of SO2 from the eruption was clearly identified in satellite observations. The simulation results were compared to satellite observations for cloud to check how the observed difference in cloud properties between in and outside the volcanic plumes was reproduced in the simulations. The simulation considering effects of volcanic smokes replicated the observed increase in Nd in the plumes. However, the same simulation overpredicted increase in significantly LWP and slightly in cloud fraction.
Study the Relation between Fatigue, Sleepiness and Accidents among the workers of Indian Weaving Industries

It has been found that shift work can disrupt human circadian rhythms which are normally acclimated to daytime wakefulness and nighttime rest. At physiological level, medical investigations have demonstrated that circadian de-synchronization can lead to changes in hormonal levels, increase risk of cardiovascular disease, produce sleep-cycle disturbances and result in significant fatigue. Shift work is growing in modern society as an important tool for flexibility of work organization. The aim of this study was to examine the rate of exhaustion and sleepiness around the shift and non-shift workers and its relation to occupational accidents. This was a cross-sectional study on the workers of Indian weaving textile industrial Group. Study included 150 shift workers as the case and 141 non-shift workers as the control. A multi-part questionnaire including demographic characteristics, Piper Fatigue Scale (PFS) and Epworth Sleepiness Scale (ESS) were applied. The X2 test and t-test were used to measure differences between variables. The mean of PFS scores in the two groups was significantly different (p=0.045), but the difference in the mean of ESS scores was not significant. Shift workers with the reported accident had a higher score on fatigue than shift workers with no accident (p<0.001) whereas the difference in the number of accidents in the two groups was not related significantly to the rate of sleepiness. The rate of fatigue or exhaustion and the number of the work accidents was more in the shift workers. Also, fatigue or exhaustion had a stronger relationship with the occupational accidents as compared to sleepiness. It seems that evaluation of exhaustion as compared to sleepiness is a more accurate factor for preventing work accidents.
Cataract Surgery of Femtosecond Laser–Assisted Process

Femtosecond laser–assisted cataract surgery (FLACS) is a relatively new technology that created a broad interest among ophthalmic surgeons following its introduction. In 2011, I wrote an editorial titled “Femtosecond laser: The future of cataract surgery” [1]. My concluding statements in this editorial read “Only time will tell whether this laser technology will be adapted into standard ophthalmic practice in the same way that phacoemulsification supplanted ECCE (Extra Capsular Cataract Extraction) in the treatment of cataracts. The technology has several potential advantages in the performance of quality cataract surgery. Its adaptation to the field of cataract surgery must still be determined. ” In the 7 years since this editorial, there has been a period of excitement regarding this new technology among ophthalmologists followed by a period of less excitement and questioning of this technology. At the recent American Academy of Ophthalmology meeting in Chicago, there was a session titled “Cataract controversies on trial. ” One of the areas of controversy was a pointcounterpoint presentation, which on one hand stated “FLACS will bring people flocking,” and on the other hand, stated “FLACS will die a slow death. ” Following these two presentations, the audience was asked to vote on which of the two viewpoints they agreed with and the majority voted that FLACS will die a slow death.
Hydrodynamics of swimming microorganisms in complex fluids

Li, Gaojin PhD, Purdue University, December 2016. Hydrodynamics of Swimming Microorganisms in Complex Fluids. Major Professor: Arezoo M. Ardekani, School of Mechanical Engineering. Swimming motion of microorganisms, such as spermatozoa, plankton, algae and bacteria, etc., ubiquitously occurs in nature. It affects many biological processes, including reproduction, infection and the marine life ecosystem. The hydrodynamic effects are important in microorganism swimming, their nutrient uptake, fertilization, collective motions and formation of colonies. In nature, microorganisms have evolved to use various fascinating ways for locomotion and transport. Different designs are also developed for the locomotion of artificial nanoand microswimmers. In this study, we use several different computational models to investigate the behavior of microswimmers. Microorganisms typically swim in the low Reynolds number regime, where inertia is negligible. They interact with each other, surfaces and external flow field. Microorganisms often swim in complex fluids, exhibiting non-Newtonian behavior, including viscoelasticity and shear-thinning viscosity. These biological materials contain network of glycoprotein fibers and gel-like polymers. Therefore on the scale of microorganisms, their fluid environments are heterogeneous rather than homogenous. In this study, we develop a computational platform to investigate swimming motion of a single and multiple microorganism(s) in the bulk fluid and near surfaces in complex fluids. We also investigate the role of fluid rheological properties and flow field on the migration of inert particles in a channel flow of viscoelastic fluids.
Post-Transplant Lymphoproliferative Disorders Arising after Allogeneic Hematopoietic Cell Transplantation: A Comprehensive Review

Post-Transplant Lymphoproliferative Disorder (PTLD) is a heterogeneous disorder that complicates both Solid Organ Transplantation (SOT) and Allogeneic Hematopoietic Cell Transplantation (allo-HCT). While the characterisitcs of SOT and HCT- PTLD are similar, important differences include lower incidence, early onset, rare graft involvement and donor origin for HCT-PTLD. Up to 10-20% of PTLD cases can lack tissue expression of EBV (EBV- PTLD); the response of EBV- PTLD to reduction in immunosuppression and treatment with rituximab is similar to that of EBV+ PTLD. In the allo-HCT, advanced age, T cell depletion ( in-vivo or ex-vivo ), use of unrelated and cord blood donors as the graft source, and transplant from HLA mismatched donors, are each associated with an increased incidence of PTLD. However, these risk factors cannot be easily extrapolated, as for example use of post-transplant cyclophosphamide for GvHD prophylaxis in the haploidentical allo-HCT is not associated with an increased risk of PTLD. While most PTLD arise from B cells, T or NK-cell PTLD constitute approximately 10-15% of all PTLD and are associated with extranodal involvement, aggressive course and poor survival. The revised World Health Organization (WHO) classification from 2016 categorizes PTLD into 6 subgroups, ranging from plasmacytic hyperplasia to classical Hodgkin lymphoma. Serial EBV DNAemia monitoring by PCR is effective in facilitating diagnosis but early recognition due to elevated EBV DNAemia alone has failed to significantly improve outcomes. It is essential to confirm the diagnosis and determine PTLD subtype by biopsy in order to deliver the most appropriate therapy as anti-CD20 monoclonal antibody therapy is generally effective but not for the PTLD subtypes of classical Hodgkin lymphoma PTLD. New approaches include cellular therapy with EBV-specific cytotoxic T lymphocytes.
The Journal of Toxicological Sciences

Prenatal diesel exhaust (DE) exposure is associated with detrimental health effects in offspring. Although previous reports suggest that DE exposure affects the brain of offspring in the developmental period, the molecular events associated with the health effects have largely remained unclear. We hypothesized that the DNA methylation state would be disrupted by prenatal DE exposure. In the present study, the authors examined the genome-wide DNA methylation state of the gene promoter and bioinformatically analyzed the obtained data to identify the molecular events related to disrupted DNA methylation. Pregnant C57BL/6J mice were exposed to DE (DEP; 0.1 mg/m3) in an inhalation chamber on gestational days 0-16. Brains were collected from 1-day-old and 21-day-old offspring. The genomewide DNA methylation state of the brain genome was analyzed by methylation-specific DNA immunoprecipitation and subsequent promoter tiling array analysis. The genes in which the DNA methylation level was affected by prenatal DE exposure were bioinformatically categorized using Gene Ontology (GO). Differentially methylated DNA regions were detected in all chromosomes in brains collected from both 1-day-old and 21-day-old offspring. Altered DNA methylation was observed independently of the presence of CpG island. Bioinformatic interpretation using GO terms showed that differentially methylated genes with CpG islands in their promoter were commonly enriched in neuronal differentiation and neurogenesis. The results suggest that prenatal DE exposure causes genome-wide disruption of DNA methylation in the brain. Disrupted DNA methylation would disturb neuronal development in the developmental period and may be associated with health and disease in later life.
Aging Kinetics of Human Hearts and Skin: New Aging Theories and Implications in the Use of Sunscreens

Published data on cardiac indexes and superficial nutritive capillary densities from photo-protected and photo-exposed areas as well as collagen contents of skin of forearms from a large number of normal subjects over several decades of lifespan were reanalyzed using a first-order kinetic model. Excellent logarithmic linear fittings were all obtained. Slopes from the photo-protected and photo-exposed studies were virtually parallel. These results appear to directly contradict the widely accepted theory of accelerated aging. It also indicates an apparent lack of effects of mild or moderate sunray exposure on skin aging and appears to contradict the conventional skin aging theory that photoaging or sunray exposure is responsible for about 80 to 90% of total skin aging. In view of many reported health benefits of UV radiation the common practice of using sunscreens can now be seriously questioned, and in fact it may be harmful to one’s health. New theories for heart aging and skin aging are postulated. Cardiac index is proposed as an aging marker for studying body aging and enhancement of cardiac index may be explored to enhance health and increase life expectancy. Reversibility of skin aging is re-considered.
Strategic management: A perspective on the development of the field of strategic management and the contribution of the Irish Journal of Management

Abstract This paper analyses the progress made in the field of strategic management over the past three decades. One approach to analysing a discipline’s trajectory is to explore its exemplary research. We review the papers awarded the Dan and Mary Lou Schendel, Strategic Management Society (SMS) Best Paper Award of the Strategic Management Journal (SMJ) since 1993, to demonstrate the emergence of strategic management as a specific discipline with a distinct view of how firms generate competitive advantage. Our paper interprets the development of the discipline from its market-based and structural roots to attempts to decipher the ‘black box’ of the organisation in analysing capabilities, particularly dynamic capabilities, and resources. Our study shows how the conceptual breakthroughs of the exemplary papers are further developed by the field through theory testing and extension using increasingly sophisticated methodologies published by journals such as Irish Journal Of Management (IJM). Our review of both journals highlights that despite increasing market, social and cultural instability since these seminal papers were first conceived, their lessons are still relevant and increasingly critical to both theory and practice in establishing the future trajectory for strategic management and a framework for organisations to compete.
Health impacts of aWISE: a longitudinal study

Purpose – This paper aims to report findings from the first year of the Vanguard Laundry evaluation study, which explores the impacts of a work integration social enterprise (WISE) on health. Design/methodology/approach – Drawing on social determinants of health (SDH) conceptual framework, a mixed-methods longitudinal case study is used to evaluate the health impacts of a WISE employing people with lived experience of mental illness. In stage one of this study, 31 participants including staff and managers completed semi-structured interviews, validated health and well-being measures and a questionnaire based on the organisation’s theory of change. Quantitative data were analysed descriptively, and qualitative data are analysed thematically. Findings – Data provided further evidence of the conceptualised WISE pathways for impact on SDH through employment, social integration, increased income, improved social position and living conditions. While social enterprise (SE) beneficiary staff had lower well-being scores than other staff members and management, the majority reported improved health, increased social supports and enhanced well-being through improvedmaterial conditions and increased sense of purpose, confidence and social connection. Research limitations/implications – Stage one of this study relied on self-reported data. Future stages will incorporate income support and health data extracted from government agencies with participant consent. Originality/value – This paper responds to calls for longitudinal studies that include a range of participants and use health outcome measures to further explore how a WISE impacts health through acting on SDH.
Liaison nursing for stroke patients: results of a Dutch evaluation study

Liaison nursing for stroke patients: results of a Dutch evaluation study Liaison nurses, employed by a home care organization, were introduced into two Dutch hospitals to improve discharge planning for stroke patients. The main aim of the study presented was to gain insight into the effects of liaison nursing on the quality of the discharge process and related outcomes. After the introduction of liaison nursing, hospital nurses completed a questionnaire on satisfaction with the liaison nurse. In addition, both before and after the introduction of liaison nursing, two groups of discharged stroke patients were interviewed by telephone. The records of these patients were also studied with respect to background characteristics and duration of hospital stays. The hospital nurses were, generally, positive about the liaison nurse and the job she did (e.g. they found that home care was better organized). Further, after the introduction of liaison nursing, more patients stated that their post-discharge needs had been discussed not later than 48 hours prior to discharge, and more patients said their aftercare had been discussed with community nurses. However, the number of patients whose medication had arrived at home on time had decreased. The results also indicated that there was no significant difference in the duration of stay between the before and after group. overall conclusion that the been moderately successful in their However, since the in only two hospitals, findings may not be representative of other settings. Future research on liaison nursing is therefore recommended.
Factors Influencing Social Media Addiction among G.C.E. Advanced Level Students in Sri Lanka: A Case Study in Colombo District, Sri Lanka

Social Media Addiction is regarded as a form of psychological or behavioral dependence on social media platforms driven by an obsessive, uncontrollable urge to use social media. Typically, young people addicted to social media are more likely to report poor mental health including psychological distress. Bergen Social Media Addiction Scale (BSMAS) is a distinct measurement used to evaluate the addiction level of a particular individual. According to Data Reportal (2020), social media penetration in Sri Lanka stands at 30 percent including a majority of youngsters. Since G.C. E. Advanced Level examination is a critical examination instrumental in pursuing higher education, it is of great importance to identify significant factors affecting social media addiction among Advanced Level students. A sample of 250 students was drawn using multi-stage clustering from Colombo district which recorded the highest internet usage in 2018. The primary data were collected through online and questionnaire surveys. To achieve the main objective, factor analysis and binary logistic regression were used. It was revealed that peer influence, entertainment, and owning a smartphone positively affected the total students' social media addiction. When it comes to female students, parent and peer utilization of social media and online interpersonal relationships were identified as important factors. Similarly, peer influence, subject stream, and owning a smartphone were identified as influential factors for male students' addiction. It was further revealed that male students who were studying in the art stream and technology stream had a higher possibility of addiction compared to that of the physical science stream. The overall research provides important recommendations on possible actions to prevent addiction.
LAYERED SOLUTIONS TO THE VECTOR ALLEN-CAHN EQUATION IN R 2 . MINIMIZERS AND HETEROCLINIC CONNECTIONS

Let W : R m → R be a nonnegative potential with exactly two nondegenerate zeros a − (cid:54) = a + ∈ R m . We assume that there are N ≥ 1 distinct heteroclinic orbits connecting a − to a + represented by maps ¯ u 1 ,. , ¯ u N that minimize the one-dimensional energy J R ( u ) = (cid:82) R ( | u (cid:48) | 2 2 + W ( u )) ds . We ﬁrst consider the problem of characterizing the minimizers u : R n → R m of the energy J Ω ( u ) = (cid:82) Ω ( |∇ u | 2 2 + W ( u )) dx . Under a nondegeneracy condition on ¯ u j , j = 1 ,. ,N and in two space dimensions, we prove that, provided it remains away from a − and a + in corresponding half spaces S − and S + , a bounded minimizer u : R 2 → R m is necessarily an heteroclinic connection between suitable translates ¯ u − ( · − η − ) and ¯ u + ( · − η + ) of some ¯ u ± ∈ { ¯ u 1 ,. , ¯ u N } . Then we focus on the existence problem and assuming N = 2 and denoting ¯ u − , ¯ u + the representations of the two orbits connecting a − to a + we give a new proof of the existence (ﬁrst proved in [32]) of a solution u : R 2 → R m of ∆ u = W u ( u ) , that connects certain translates of ¯ u ± .
Effects of La3+ on Surface Charges, Dielectrophoresis, and Electrofusion of Barley Protoplasts1

When dielectrophoresis and electrofusion of barley (Hordeum vulgare var Moor) leaf protoplasts were assayed in the presence of 0.1 to 1 millimolar lanthanum ion (La3+) in the basal medium (0.7 molar mannitol, 1 millimolar piperazine-N,N-bis[2-ethanesulfonic acid]-Na [pH 6.7], 0.1 millimolar CaCl2), dielectrophoresis and induction of electrofusion were strongly inhibited. The latter remained inhibited and the former recovered by about 60% after washing the La3+-treated protoplasts without EDTA. These inhibitions were almost completely abolished by washing the La3+-treated protoplasts with 1 millimolar EDTA. Inductively coupled plasma atomic emission spectroscopic analysis revealed that protoplasts retained a considerable amount of La3+ after washing without EDTA and released most of the bound La3+ by washing with 1 millimolar EDTA. This tightly bound La3+ seemed responsible for the inhibition of electrofusion and dielectrophoresis that was observed in the La3+-treated protoplasts after washing. {-potentials of protoplasts were -39.0 ± 3.2 millivolts, -16.7 ± 2.6 millivolts, and virtually zero in media containing 0, 0.1, and 0.3 millimolar La3+ (I= 7.2 millimolar), respectively, and had a positive value (+ 14.2 ± 2.2 millivolts) in the presence of 1 millimolar La3+. These effects of La3+ on {-potentials were easily abolished by washing without EDTA. This indicates that charged species located at the surface of plasma membrane of protoplasts cannot account for the sites at which La3+ exerts its inhibition of dielectrophoresis and electrofusion. In contrast, the promotion of spherical fusion and the reduction of broken fusion products observed in the presence of La3+ were almost completely abolished by washing without EDTA. Our results also indicate that the initial induction and development of electrofusion can be studied independently.
Evaluation of Clinical & Etiological Profile of Children with Seizures

Background: Seizures are a transient occurrence of signs and/or symptoms resulting from abnormal excessive or synchronous neuronal activity in the brain. Better understanding of seizures in terms of clinical presentation and etiology is required not only for abortion of acute attack but also for long term control of epilepsy. Subjects and Methods: This retrospective observational study included those children who were admitted with seizures within last 1 year time period of our study. Variables including age, sex, type of seizure, laboratory test results, neuroimaging, EEG findings, duration of hospital stay, diagnosis and final outcome were studied. Results: Incidence of seizures decreased with increasing age with less than 5 years age group most commonly involved. Generalized tonic clonic seizure were the most common type of seizure with febrile seizures being most common. etiology followed by CNS infections. Febrile seizures had best outcome while CNS infections had highest morbidity and mortality. Conclusion: We found CNS infections to be the most common etiology and a poor outcome. Acute episode of seizures is one of the commonest causes of hospitalization with high morbidity and mortality. Being a developing nation, strict measures to prevent infection can reduce the occurrence of seizures in children thus preventing long term neurological sequelae in children.
Understanding the Underrepresentation of Qualitative Research Approaches to Built Environment Research in Nigeria

ABSTRACT There is evidence that scholars in some countries, including Nigeria, primarily employ the quantitative approach to research, and that in some cases this approach is used inappropriately. This leaves research questions that should be tackled from a qualitative standpoint either unaddressed or incorrectly addressed. The aim of this study is to understand why the qualitative approach (QA) has failed to gain similar recognition in Nigeria and other countries, and by extension, the disposition of researchers towards its use. The impact of the disposition of researchers toward QA was also explored. Researchers in the various built environment (BE) disciplines in Nigeria were interviewed. The results revealed that there is a preference for quantitative research, while QAs are used if convenient. Furthermore, the study revealed that the educational background of academics and their poor understanding of the qualitative paradigm explain their disposition toward the adoption of the QA in research. This finding suggests that academic followers instead of leaders are being produced, and that research is done for ad hominem promotion. In advancing the understanding of QA in BE research in Nigeria, this study also draws the attention of stakeholders in the academia to the implications of a preference by researchers for quantitative research.