Miracle-dz/UniFAR-FTUs huggingface dataset:
DIAGNOSIS AND TREATMENT OF DEPRESSION IN PERSONS WITH INTELLECTUAL DISABILITY

This paper considers, from the theoretical point of view, the problem of diagnosing and treatment of depressive disorders in people with intellectual disability (ID), relying primarily on the results of previous researches, which stress the etiological, symptomatic, diagnostic and therapeutic specifics when it comes to depression and its correlates in this population. The interest in mental health and psychopathology of people with ID intensified during the seventh decade of the previous century, when it became clear that some cognitive and behavioral symptoms are not, as hitherto thought, only a part or a consequence of the syndrome of intellectual disability, but a sign of ongoing mental disorder. So, the idea of ''dual diagnosis'' was born, and now it provides guidelines for the growing number of studies which theoretically and empirically review different issues of mental health problems in people with ID. Likewise, the observation of syndrome groups of genetic disorders resulting in intellectual disability has led to the narrowing of the circle of genetic syndromes that carry increased risk for the onset of depression and its correlates, such as: Down syndrome, Fragile X syndrome and Prader-Willi syndrome. Potential diagnostic problem in people with ID, when it comes to depression, may arise from ''diagnostic overshadowing’’ of depression symptoms, which often remain hidden under abnormal behavior and adjustment disorders, especially in patients with severe forms of ID. As a possible way to overcome these problems some authors have proposed the concept of ''behavioral equivalents of depression'' or behavioral disorders that evidently can be associated with depression, such as social withdrawal, aggression, hostility, irritability, psychomotor agitation or retardation. Intensification of these forms of behavior may be a sign of developing depression, and in that sense, this view represents a useful starting point. When it comes to therapeutic approaches, there is a general tendency in favour of psycho pharmacotherapy in the treatment of depression, although there is a growing number of researches that prove the favourable effects of cognitivebehavioral and psychoanalytic psychotherapy. Acta Medica Medianae 2011;50(3):81-89.
The measurement and clinical significance of the Han and Uigur female pelvis in the region of Xinjiang.

Objective To investigate the anatomical characteristics and the clinical significance of the Han and Uigur female pelvis in the region of Xinjiang. Methods The pelvis of child-bearing period women were studied and divided into 3 groups: Xinjiang Han group,Xinjiang Uigur group and The Han group in the South,then the obstetric diameters were observed and analyzed by using the methods of three-dimensional reconstruction and three-dimensional measurement. Results The percentage of sacrococcygeal joint abnormalities in Xinjiang Uigur group are more remarkably increased (P0.05) than that of the other groups. Differences are significant in obstetric diameters in the plane of pelvic inlet between the Han nationality group and Uigur ethnic group (P0.05),but there is no significant difference about the diameters in other planes. The sagittal entrance diameter of Xinjiang Han group are shaply increased(P0.05) and the conjugate of the inlet decreased(P0.05) compared with that of the South Han group. Conclusion Female pelvis has its own characteristics ,racial differences and regional differences,so we should pay a attention to these differences in clinical work.
Current issues in IT education

Addressing the ongoing quest for teaching excellence in an increasingly technological society, the information presented in this volume addresses how to effectively implement teaching technologies across disciplinary boundaries. The scholarly dimensions of belief, inquiry, argument, and reflection in information systems are presented with attention to educational theories of metacognition, technology literacy, and community informatics. Training for e-business and public agency work are discussed to better equip instructors for the distinctive information needs of these sectors.
Association between enamel hypoplasia and dental caries in primary second molars and permanent first molars: A 3-year follow-up study

Context: Enamel hypoplasia is a defect caused by disturbances during enamel formation. These defects in the enamel present important clinical significance as they predispose a tooth to dental caries. Aim: The aim of this study was to assess the longitudinal relationships between enamel hypoplasia and caries experience of primary second molars and permanent first molars. Materials and Methods: The study sample consisted of 765 subjects who underwent dental examinations at both ages 6 and 9 by the calibrated examiner. Primary second molars and permanent first molars were scored for the presence of enamel hypoplasia for each participant. Caries presence and number of decayed and filled surfaces (dfs and DFS) were determined at ages 6 and 9. The relationships between enamel hypoplasia and caries experience were assessed using multivariable regression models. Results: At the tooth level, 2.8% and 3.5% of children had hypoplasia on primary second molars and permanent first molars respectively. Multivariable logistic regression analyses showed that children with enamel hypoplasia were at a significantly higher risk of caries at both ages 6 (odds ratio, OR = 5.27 for primary second molars and OR = 3.21 for permanent first molars) and age 9 (OR = 3.45 for primary second molars and OR = 4.57 for permanent first molars), and that a statistically significant association was seen with caries incidence (OR = 2.08 for primary second molars and OR = 2.87 for permanent first molars). Conclusion: Enamel hypoplasia appears to be a significant risk factor for caries in both primary second molars and permanent first molars and should be considered in caries risk assessment.
Changes in Pediatric Gastrointestinal Endoscopy: Review of a Recent Hospital Experience

Purpose: This study was performed to review the recent experiences of pediatric gastrointestinal (GI) endoscopy done in one university hospital. Methods: A retrospective review of medical records was conducted of 1,040 pediatric cases who underwent GI endoscopy at the Pusan National University Hospital between January 2001 to June 2005. Results: A total of 1,040 endoscopies (upper 840 and lower 200) were performed. The male/ female ratio was 1.25:1. Neonates and infants accounted for 6.0% and 16.5% respectively. Half of the children were below 5 years (mean age 8.5±2.1 years). Upper and lower GI diagnostic endoscopies were performed in 634 and 163 children respectively. Abdominal pain (38.8%), vomiting (19.4%), foreign body (17.7%), and hematemesis (10.3%) were the main reasons for esophagogastroduodenoscopy. Hematochezia (56.0%), abdominal pain (27.5%) and diarrhea (3.0%) were the main reasons for colonoscopy. Upper GI therapeutic procedures included retrieval of foreign bodies, balloon dilatations of esophageal stricture, PEG, and variceal ligation in 148, 27, 15, and 3 children, respectively. Therapeutic lower GI endoscopies were performed in 37 children (polypectomy in 92%, argon lazer cauterization for angiodysplasia in 4%). Conclusion: GI endoscopy played an important role in the diagnosis and treatment of GI diseases in children. Procedures in younger aged children, cases evaluated by colonoscopy and therapeutic endoscopies are increasing in pediatric practice. (Korean J Pediatr Gastroenterol Nutr 2007; 10: 20∼27)
An Evaluation Of An Afterschool Program In a Title 1 Elementary School

i PREFACE . ii ACKNOWLEDGEMENTS . iv DEDICATION . v CHAPTER ONE: INTRODUCTION . 1 Purpose of the Evaluation . 5 Rationale . 14 Goals of the Program Evaluation . 17 Exploratory Questions . 23 Primary Exploratory Questions . 23 Secondary Questions . 24 Conclusion . 24 SECTION TWO: REVIEW OF LITERATURE . 26 Introduction . 26 Prevalence of Afterschool Programs . 26 History of 21 CCLC . 28 Student Characteristics in the Program. 30 Role of Academics in Afterschool Programs . 32 Relationships between Students and Staff in the Program . 35 Parental Involvement in Afterschool Program . 35 Conclusion . 40 SECTION THREE: METHODOLOGY.41 Research Design Overview . 41 Participants . 43 Data Gathering Techniques . 44 Participant Surveys . 45 Principals, Assistant Principal, Counselor Survey . 46 Teachers Survey . 46 21st CCLC Staff Survey . 47 21st CCLC Parent Survey . 47
The Impact of Yoga on the Quality of Life and Functional Performance of Chinese Older People

Results and conclusions: A total of 127 completed the main study, with the attrition rate of 5.9%. After 12 weeks of intervention, significant differences were found in the overall physical (p=0.015) and mental components (p=0.023) in the summary measures of SF-36 between the intervention and control groups. Significant improvement was likewise observed in TUGT (p<0.001) but not in OLST results (p=0.438) of the intervention group. Innovation: A 12-week yoga programme could improve the quality of life and gait speed of the participants. Positive information about the benefits of this exercise should be promoted.
THU0344 DAS-28, SDAI and CDAI in the patients with rheumatoid arthritis and concomitant fibromyalgia

Background Composite indices DAS-28 (Disease Activity Score, assessing 28 joints), SDAI (Simplified Disease Activity Index), CDAI (Clinical Disease Activity Index) are widely used instruments for the assessment of disease activity in the patients (pts) with rheumatoid arthritis (RA), but they may not be sufficient to evaluate activity in cases of RA associated with chronic pain syndromes such as fibromyalgia (FM). Objectives To examine the FM impact on disease activity composite indices in pts with RA. Methods We examined 120 pts (29 males, 91 females) with RA on the presence of concomitant FM according the ACR criteria (1990). All the patients were examined by the same rheumatologist, assessing TJC (tender joint count), SJC (swollen joint count) and TPC (tender point count). Laboratory parameters included erythrocyte sedimentation rate (ESR), C-reactive protein (CRP), rheumatoid factor (RF) and anti-citrullinated peptide antibody (ACPA). RA activity was evaluated by three composite indices (DAS-28, SDAI and CDAI) and functional disability by Health Assessment Questionnaire (HAQ). Results The diagnosis of FM was established in 25 (20.8%) pts with RA (RAF), 4 men and 21 women. RA and RAF pts did not differ significantly in sociodemographic characteristics (age, eduacation, marital status, RA duration), laboratory inflammatory markes, RF and ACPA seropositivity. RAF pts in comparison to RA pts were found to reach significantly higher scores in all three composite indices (DA-28 5.35±1.1 vs. 3.67±1.4, p<0.0001; SDAI 31.8±10.9 vs. 13.5±10.8, p<0.0001; CDAI 29.6±10.7 vs. 11.8±9.4, p<0.0001) and in disability level (HAQ 1.83±0.64 vs. 0.87±0.76, p<0.0001). Detailed analysis revealed that TJC and VAS-GH (patient’s global health on a 100 mm visual analog scale) contributed mostly to the disease activity diferencies in RA and RAF, but doctor’s global health VAS was also significantly increased in pts with RAF in comparison to RA. Conclusions Rheumatologists, using disease activity composite indices in a daily clinical practice and clinical trials, should be aware of the limitations when these indices do not reflect real inflammatory activity but result from measurements dependent on an individual patient’s pain perception. Disclosure of Interest None Declared
LATE-BREAKING ABSTRACT: A novel role for CCR3 in promoting airways hyperreactivity; Role for CCR3-muscarinic M3 receptor heterodimers

We have developed a novel therapeutic inhibitor against the chemokine receptor CCR3 for allergic asthma that significantly inhibited the MCh PC 20 response in a Phase IIa trial in mild-to-moderate asthmatics. In vivo , AXP1275 had shown significant efficacy in reducing inflammatory mediators and cellular infiltrates in non-human primate models of allergic asthma, and, surprisingly, had also inhibited airways hyperreactivity and methacholine constriction responses (PC 150 ). In addition, inhibition was seen with ex-vivo carbachol (CCh)-induced constriction in human lung tissue. In order to discern pharmacologically-relevant mechanisms for inhibition of CCh-induced lung constriction by AXP1275, we have investigated the receptor pharmacology of CCR3 in human lung tissue. Immunohistochemically, CCR3 is present on epithelium and smooth muscle, and is co-localized with the muscarinic M3 receptor. In receptor transfectants, CCL11 and CCh cross-sensitize agonist-induced calcium mobilization, suggesting cooperativity between CCR3 and M3. AXP1275 and muscarinic receptor antagonists inhibit responses in a similarly-cooperative manner. Bioluminescence resonance energy transfer (BRET) assays demonstrated that CCR3 and M3 heterodimerize, and this was further supported by receptor co-immunoprecipitation assays. Receptor heterodimerization of CCR3 and M3 on non-leukocytic cells in vivo may provide a plausible explanation for the efficacy of CCR3-selective inhibitors on the hyperreactivity response in asthma.
An essay on the principle of population : or, A view of its past and present effects on human happiness; with an inquiry into our prospects respecting the future removal or mitigation of the evils which it occasions.

Published in two volumes, these books provide a student audience with an excellent scholarly edition of Malthus' Essay on Population. Written in 1798 as a polite attack on post-French revolutionary speculations on the theme of social and human perfectibility, it remains one of the most powerful statements of the limits to human hopes set by the tension between population growth and natural resources. Based on the authoritative variorum edition of the versions of the Essay published between 1803 and 1826, and complete with full introduction and bibliographic apparatus, this edition is intended to show how Malthusianism impinges on the history of political thought, and how the author's reputation as a population theorist and political economist was established.
Fabrication and Observation of Clinical Application of Xenogeneic Acellular Dermal Matrix

Objective To reduce the antigen of allogeneic dermis and investigate its availability for comoposite transplantation. Methods Split-thickness skin grafts from common swine were divided into two groups with or without glutaraldehyde cross-linking treatment. Then the cross-linked sADM (sADM1) and non cross-linked sADM (sADM0) were embedded subcutaneously in rabbits and transplanted after scar was excised off. The histological observation was performed to determine the results of sADM1 and sADM0 after transplantation. Results The sADM0 with severe immune response were infiltrated by autologenous tissue cells in the early phase after embeded in rabbits. Furthermore, the degeneration and contraction of sADM0 were observable. By comparison, the sADM1 with less histocompatibility, slight immune response, and unobservable degeneration and contraction, showed comparatively complete appearance and histological structure till 30 weeks after embedment. sADM overlaid with auto-over thin split-thickness skin (OTS) were compositely transplanted onto the wounds. The survival rate was about 78.9% similar to that of auto-thin split-thickness skin (TTS). In the group of sADM0 overlaid with OTS, the survived grafts showed an early immune response and observable contraction, and appeared like OTS after transplantation. In the group of sADM1- overlaid with OTS, the survived grafts with slight early immune response and contraction locked flat and touched soft as TTS. Conclusion The sADM1 used as dermal substitute of composite skin could retard the early immune response and improve the result of OTS transplantation, but couldn't completely prevent delayed heterogeneous rejection, indicating the sADM need to be improved.
Effects of structure on hydrogel microbead function

Hydrogel microbeads are capable of trapping, protecting and delivering components. We investigated how different production parameters influenced the microstructure of protein and polysaccharide hydrogel microbeads, and how that in turn influenced the functional properties of the microbeads as encapsulation devices in various systems. We found that by changing the production method and the hydrocolloid type and density we could create a variety of structures with different strengths, breakdown patterns and diffusivity profiles. Most importantly, the functionality of the hydrogel microbeads is not dependent on the individual production parameters, but on a system in which the hydrogel matrix, the diffusing compound moving into or out of the microbead, and the environment in which the microbead is present, all play varying but important roles in the complete system. The hydrogel microbead by itself is a viable encapsulation device but may also be the basis for a more complex encapsulation system in which several components may be encapsulated together and which may be triggered to release by outside influences.
Knowledge and Attitudes of Women about Breast Cancer, Self Breast Examination and Healthy Life Style Behaviours

Objective: The present study was conducted to determine the knowledge and attitudes of female students, who have just started to attend university, about breast cancer, self breast examination and healthy life style behaviours. Materials and Methods: This descriptive study consisted of 384 female university students who started to attend Erciyes University in the 2009-2010 academic year. Three hundred and thirty one women were included in the study. Data were collected with an Individual Information Form including questions regarding socio-demographic characteristics, with a Questionnaire Form to determine knowledge and attitudes of women about breast cancer and self breast examination and with a Health Promoting Life Style Profile Scale (HPLP-II) to determine healthy life style behaviours. Data were analyzed with mean and percentage values, Mann Whitney U and Kruskal Wallis H tests on SPSS version 17.0 package program. Results: The mean age of the women was 19.37±1.3 (min-max) years. It was determined that the majority of women had inadequate knowledge about symptoms of breast cancer, the population at risk and how to do the self breast examination. Of the women, 13.3% did self breast examination. Women who knew women with breast cancer carried out significantly more self breast examinations (p<0.05). The total scores of HPLP-II Scale of women were significantly different between knowledge about breast cancer and knowing the importance of early diagnosis in breast cancer (p<0.05). Conclusion: As a consequence, it may be concluded that educating women about breast cancer and self breast examination at younger ages is important in order to achieve early detection of breast cancer, which is common among women.
An Exploratory Study of the Impact of e‐Service Process on Online Customer Satisfaction

Although extensive academic research has examined the dynamics of interpersonal interactions between service providers and customers, much less research has investigated customer service encounters through technological interfaces such as the Web in electronic commerce transactions. Corporate websites have become an important point of contact with customers for many companies. Service has been described as one of the most important attributes for online business to influence traffic and sales. However, more research is needed to understand how Web‐based technological capabilities of services affect customer satisfaction. In this paper, we propose viewing the interface between online buyers and sellers through the lens of service management to identify possible determinants of online customer satisfaction. A company's website is considered its electronic service delivery system. We look at this electronic service delivery system from its process point of view. Our findings indicate that as the electronic service delivery system process improves, a customer's perception of the website's ease of use increases, leading to increased service value and perceived control over the process, which increases customer satisfaction. The research provides evidence that the technological capabilities embedded in the website processes are an important factor in determining service quality and ultimately online customer satisfaction.
Empirical analysis of the intrinsic–extrinsic distinction of judgments of learning (JOLs): Effects of relatedness and serial position on JOLs.

: A. Koriat's (1997) cue-utilization framework provided a significant advance in understanding how people make judgments of learning (JOLs). A major distinction is made between intrinsic and extrinsic cues. JOLs are predicted to be sensitive to intrinsic cues (e.g., item relatedness) and less sensitive to extrinsic cues (e.g., serial position) because JOLs are comparative across items in a list. The authors evaluated predictions by having people make JOLs after studying either related (poker-flush) or unrelated (dog-spoon) items. Although some outcomes confirmed these predictions, others could not be readily explained by the framework. Namely, relatedness influenced JOLs even when manipulated between participants, primacy effects were evident on JOLs, and the order in which blocks of items were presented (either all related items first or all unrelated items first) influenced JOLs. The authors discuss the framework in relation to these and other outcomes.
Delivery Room Management of RDS

Respiratory Distress Syndrome RDS is a leading cause of short and long term morbidity and mortality in the preterm neonate. While the discovery and use of surfactant for RDS has improved neonatal survival as a whole, there are a variety of aspects of delivery room care that can improve outcomes further. In this article we will review evidence to optimize delivery room care of pre term neonate with RDS. *Corresponding author: Saima Aftab, MD, Assistant Professor of Pediatrics, Children’s Hospital of Philadelphia, Perelman School of Medicine, University of Pennsylvania, USA, E-mil: saima.aftabmd@gmail.com Received March 16, 2013; Accepted June 13, 2013; Published June 17, 2013 Citation: Aftab S, Gerdes JS (2013) Delivery Room Management of RDS. J Pulmon Resp Med S13: 003. doi:10.4172/2161-105X.S13-003 Copyright: © 2013 Aftab S, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.