Miracle-dz/UniFAR-FTUs huggingface dataset:
Changes in Quality of Sleep, Mood, and Other Neuropsychiatric Symptoms After Switching Dolutegravir/Lamivudine/Abacavir to Darunavir/Cobicistat/Emtricitabine/Tenofovir Alafenamide in a Randomized Study of People With Human Immunodeficiency Virus With Poor Sleep Quality: GESIDA 10418

Abstract Background Although switching antiretroviral therapy (ART) in people with human immunodeficiency virus experiencing insomnia due to dolutegravir-related neurotoxicity is well founded upon evidence, there is a lack of proof in regard to the outcome of stopping dolutegravir-based ART in people without insomnia but reporting poor sleep quality. Methods This is a randomized, multicenter, open-label study to evaluate the reversibility of patient-reported sleep disturbances in patients on dolutegravir/lamivudine/abacavir without insomnia after switching to darunavir/cobicistat/emtricitabine/tenofovir alafenamide. The participants were randomized to switch ART at baseline or at week 4 and then completed 8 weeks of darunavir/cobicistat/emtricitabine/tenofovir alafenamide. Our primary objective was to compare changes in sleep quality between arms at week 4. Secondary objectives were to compare changes in mood and neuropsychiatric symptoms (NS) at week 4 and 4 and 8 weeks after switching to darunavir/cobicistat/emtricitabine/tenofovir alafenamide. The participants completed a survey, including the Pittsburgh Sleep Quality Index (PSQI), the Hospital Anxiety and Depression scale (HADS), and specific questions to explore NS, at each visit to assess those objectives. Results We included 72 participants. The results show that study arms were similar at baseline; however, at week 4, PSQI scores remained unchanged with dolutegravir/lamivudine/abacavir, whereas patients improved significantly after switching to darunavir/cobicistat/emtricitabine/tenofovir alafenamide. Similar differences between arms were also observed in HADS and NS changes. At weeks 4 and 8 after all participants switched to darunavir/cobicistat/emtricitabine/tenofovir alafenamide, we have observed significant improvements in PSQI and HAD scores and in NS. Conclusions In patients reporting subclinical sleep disturbances without insomnia, switching from dolutegravir/lamivudine/abacavir to darunavir/cobicistat/emtricitabine/tenofovir alafenamide was associated with better sleep quality and improvements in mood and NS.
Updates on COVID-19: Virology, Etiology, Epidemiology, Pathogenesis, Diagnosis, Transmission and Prevention

COVID-19 is a pandemic malady caused by SARS-CoV-2, a novel coronavirus. It is a global threat that has affected 223 countries and territories all over the world. According to the WHO report as of April 06, 2022 coronavirus has affected 492,189,439 people globally with 6,159,474 confirmed deaths. The pandemic of COVID-19 has badly affected Bangladesh likewise many other countries of the world. According to Worldometer report on 06 April 2022 the number of confirmed cases of COVID-19 were 1,951,903 with 29,123 deaths, and 1,886,036 COVID-19 recoveries in Bangladesh. After originating from China, this notorious virus has been spread to almost all the countries of the world. Its spike protein aids in binding with the ACE2 receptors of the cell membrane resulting in cell entry, replication, and induction of inflammatory and pro-inflammatory responses leading to the pathogenic condition. The novel COVID-19 virus has structural and genetic similarity with its predecessors specially SARS-CoV and MERS-CoV. This review presents the existing literature on COVID-19 and discusses different aspects of COVID-19 including virology, etiology, epidemiology, pathogenesis, diagnosis, transmission and susceptibility and preventive measures of COVID-19. Bangladesh Pharmaceutical Journal 25(2): 143-163, 2022 (July)
Effect of High-performance Work Practices on Civil Servants Health Based on Two Sides of the Job Demands-resources Model in the National Research and Innovation Agency Indonesia

The purpose of this paper is to examine the effect of High-Performance Work Practices (HPWPs) viewed from two sides of the Job Demands-Resources (JD-R) model on employee health. The proposed model was tested on 402 civil servants of the Indonesian Research and Innovation Agency. We utilized Partial Least Squares Structural Equation Modeling (PLS-SEM) to analyze the study. Our results show that HPWPs has a significant positive impact on employee health, job satisfaction, employee engagement, and challenge stressors. Besides that, we found that HPWPs has a negative impact on stressors and emotional exhaustion. In addition, job satisfaction, employee engagement, challenge and hindrance stressors become partial mediators in the positive effect of HPWPs on employee health. Meanwhile, supportive leadership tends to reduce the positive influence of HPWPs on employee health. The results of this study indicate that agencies should pay more attention to the dose of JD-R and the role of leadership in HPWPs in order to improve employee well-being. Because if job demands higher than the work resources, it has a negative impact on employees, even excessive leadership roles in the HPWPs have a negative impact on employees
Spacecraft Charging on ATS-5.

Abstract : The distribution of plasma electron and proton temperature at the time of spacecraft charging events during eclipse are obtained from ATS-5 data for 1969 to 1971. The mean RMS electron temperature is 3 keV and the highest value measure is 6.5 keV. The mean RMS ion temperature is 9 keV; the highest value is 12 keV. The current-voltage characteristic curve shows that a threshold current for charging exists which is 0.000001 A/sq m. The charging current has a narrow distribution around 0.0000015 A/sq m. The spacecraft ground potential varies approximately linearly with RMS plasma electron temperature consistent with the behavior of a dielectric probe in a plasma. (Author)
Patients' self-care for side effects of chemotherapy after mastectomy

Background: Chemotherapy is medicine used to destroy cancer cells and treat breast cancer. It is toxic to fast growing cancer cells. The aim of this study was to assess the patients 'self-care practices for side effects of chemotherapy after mastectomy. Design: A descriptive exploratory research design was utilized to achieve aim of the study. Setting: the study was conducted at the oncology outpatient breast clinics at Dar El Salam oncology center. Sample: Purposive samples of 117 patients were included in the study. Tools: Tool I: Structured interview questionnaire: Part I: Socio demographic characteristics of patients, Part II: Medical health history assessment, Part III: Patients’ knowledge regarding chemotherapy. Tool II: Patients' self-care practices assessment sheet:. Part I: Assessment of patients 'self-care practices regarding chemotherapy, Part II: Patients' daily living activities. Results: 65.0% of the studied patients had satisfactory total knowledge score regarding chemotherapy, about half them had satisfactory total self-care practices score regarding chemotherapy's side effects. Conclusion: there were highly statistically significant positive correlation between the studied patients' total knowledge regarding chemotherapy and their total self-care practices. Recommendations: Continuous evaluation of patient's' knowledge and practice is essential to identify patient's needs and factors affecting their performance & activities of daily living.
Modelling Monthly Rainfall of Calabar, Nigeria Using Box-Jenkins (ARIMA) Method

Rainfall has both positive and negative effects on human activities hence, correct prediction of the period of occurrence is very essential. However, the traditional method of predicting months of heavy rainfall is gradually fading out as irregular rainfall pattern is been experienced in most regions of the world. The rainfall pattern in Calabar city in Southern Nigeria has been reported in past literatures of being irregular. Hence, this research applied the Auto-Regressive Integrated Moving Average (ARIMA) also known as Box-Jenkins method to model the rainfall pattern of Calabar. This was achieved by subjecting 50years monthly rainfall (1971 – 2020) to gretl software version 2021b. The analysed data showed that the rainfall of the study area required just one-time differencing to attain stationarity at 95% confidence, while the order of the Auto-Regressive AR(p) and Moving Average MA(q) models were either 1 or 2 in both cases. Hence ARIMA(1,1,1), ARIMA(1,1,2), ARIMA(2,1,1) and ARIMA(2,1,2) were identified and further analyses revealed that ARIMA(2,1,2) best suited the rainfall of the study area. A diagnostic check was carried out on the selected ARIMA (2,1,2) model and it was observed to be reliable (minimal white noise) thereafter, it was used to forecast the rainfall of the study area for some months.
Pollution, Production Efficiency and Economic Growth: A Synthesis

Production efficiency of the firm is defined to be the maximum ratio of output to input in this paper. When a society reaches Pareto optima, this society achieves its aggregative efficiency. If the firm does not produce efficiently, transformation rate on production frontier does not make any sense because production frontier can be extended if the firm improves its own production efficiency. Therefore, production efficiency of the firm is the necessary condition of Pareto optima. Since total input is equivalent to total cost in the sense of aggregating different inputs, the concept of production efficiency of the firm can be mathematically converted into minimum cost (i.e., minimum input). When input is minimized, pollution that arises from production is minimized, ether. Thus, pollution is minimized by the efficient firm while the firm grows efficiently. This conclusion implies that government intervention is unnecessary. Consequently, the primary policy to reduce pollution would be promoting anti-pollution technology and subsiding the firm to upgrade its equipment as well as improving production efficiency of the firm rather than charging Pigovian tax and enforcing government regulation except that minimum pollution makes people not endure or environment not sustain. To summarize, this paper integrates efficiency, externality (e.g., pollution), market mechanism (e.g., supply and demand), government intervention (e.g., Pigovian tax), increasing return to scale and economic growth into growth model of the firm by which we are capable to propose pollution policy.
Compositional Data Analysis (CoDA) of Clinopyroxene From Abyssal Peridotites

We analyze a large database of abyssal peridotite clinopyroxene compositions using log‐ratio transformation, principal component analysis (PCA) and k‐means clustering, to better understand clinopyroxene compositional systematics in abyssal peridotites. We combine this analysis with open‐system melting models to investigate the potential sources of compositional variation. PCA shows that 84% of the variation in clinopyroxene compositions can be represented using only 2‐dimensional information. We use k‐means clustering to classify clinopyroxene compositions into four clusters. Clusters 1–3, representing 85% of the data, show progressive depletions in LREE/HREE, and are associated with decreases in Na2O in clinopyroxene, and general increases in Cr# of spinel. We interpret peridotites with clinopyroxene compositions from clusters 1–3 to represent residues of partial melt extraction. The degree of melt extraction increases from cluster 1 to 3, and exerts a primary control on compositional variations. The presence or absence of garnet‐field melting prior to spinel‐field melting and the retained melt fraction during partial melting exert secondary controls on clinopyroxene compositions. Cluster 4 clinopyroxenes, representing show less fractionated LREE/HREE with low‐HREE abundances, elevated Sr, and depleted signatures in their host peridotites. Clinopyroxene compositions in cluster 4 cannot be modeled by melt depletion alone. Instead, they are only reconstructed in our models where melt‐rock interaction, suggesting that peridotites with cluster 4 clinopyroxenes have experienced both of these processes. Clusters 1–4 are observed in most ridges, reflecting compositional heterogeneity on each ridge. This variability reflects variations in the degree of partial melting, amount of garnet‐field melting, retained melt fractions, and melt‐rock interaction.
Clinical Effectiveness of Egyptian Articaine (4% Artpharmadent) Versus Imported Articaine (4% Artinibsa) in Extraction of Primary Molars: Randomized Clinical Trial

Objective: the objective of this study is to compare the clinical effectiveness of a relatively new locally manufactured articaine (Artpharmadent 4% 1/100.000, made in Egypt) versus imported articaine (Artinibsa 4% 1:100.000, made in France) in buccal infiltration anesthesia during extraction of primary molars. Subjects and Methods: A prospective, randomized, split-mouth comparative study was conducted on children aged from 6 - 10 years old having bilateral badly decayed mandibular or maxillary primary molars. Children were randomly chosen from the outpatient clinic of paediatric dentistry department, Cairo University. Split-mouth technique was followed to give buccal infiltrations of Artpharmadent on one side and Artinibsa on the other at separate visits. Child pain and behaviour were assessed using Wong–Baker FACES pain rating scale and face, leg, activity, cry and consolability (FLACC) Behavioural Pain Assessment Scale. Results: Both anaesthetic types showed comparable and high clinical effectiveness in pain control during extraction. FLACC behavioural pain scale showed insignificant difference with both local anaesthetics. Conclusion: locally manufactured articaine buccal infiltration anesthesia is effective as imported one. It showed deep and painless alternative to anaesthetize primary molars and related supporting tissues.
On the classification of three-dimensional compact Kaehler manifolds of nonnegative bisectional curvature

After the solution of Frankel conjecture by Mori [5] and Siu & Yau [8], it is natural to consider the classification of compact Kaehler manifolds of nonnegative bisectional curvature. In this direction there are some previous works, for example, the characterization of hyperquadrics by Siu [7], and the splitting theorem of Kaehler manifolds of nonnegative bisectional curvature by Howard, Smyth, and Wu [3], [9]. Besides these general dimensional studies there is a low dimensional result by Howard & Smyth [2] that is the complete classification of two-dimensional compact Kaehler manifolds of nonnegative curvature. In this paper, proceeding in this direction, we consider the case of three-dimension and obtain some results which, combined together with the above results of Howard, Smyth and Wu, [2], [3] and [9], enable us to settle the classification of three-dimensional compact Kaehler manifolds of nonnegative bisectional curvature. Namely our goal is the following theorem. Theorem 3. Let M be a three-dimensional compact Kaehler manifold of nonnegatiυe bisectional curvature. If M has quasipositiυe Ricci curvature, then M is biholomorphic to one of the following: P 3 , Q\ P 1 X P 2 , P X P X P 1 . The author would like to thank Professor S. -T. Yau, under whose advice this work was done.
Exposure level from selected base station tower around Kuala Nerus: a preliminary analysis

Health risk due to RF radiation exposure from base station tower (BST) has been debated for years leading to public concerns. Thus, this preliminary study aims to measure, evaluate and analyze the exposure level on three selected BST around Kuala Nerus. The measurement of exposure level in terms of voltage amplitude (dBmV) data were recorded using spectrum analyzer. The trend of exposure level shows that the characteristics of environment around the BST sites contribute to the variation of voltage amplitude for all study sites. Besides, the radiation exposure level of BST depends on several factors such as: the distance from the radiation sources, the height of the tower, tilt and direction of the antennas fixed on the top of the tower, the number of antennas on single tower, the type of radiation pattern, the direction of main beam of radiation, the feeding power and the operating frequency
Orientation and Mobility Practitioners: A Comparison Study of Changes in Demographics

Introduction: Three early studies from 1974 to 2000 provided information on demographics and salient characteristics of the profession of orientation and mobility (O&M). The current study compared demographic information from those studies with data from a survey instrument administered in 2019. The purpose of this article is to examine changes in demographics that have emerged in the ensuing years. Method: The questionnaire was disseminated using Qualtrics. It was distributed to practitioners in the profession via all available professional electronic discussion groups and was advertised on the websites of the Academy for Certification of Vision Rehabilitation and Education Professionals (ACVREP) and Association for the Education and Rehabilitation of the Blind and Visually Impaired (AER). Findings: The number of O&M practitioners who responded to the survey was 628. Data indicate that the O&M profession is still predominantly Caucasian, and females continue to be in the majority and have expanded within the profession. The percentage of O&M practitioners working in school settings increased by 14% from earlier studies, and respondents had a median age of 41–50 years. Discussion: The results of this study show that the profession remains primarily female, mostly Caucasian, and 65% of practitioners are 41 year of age or older. O&M practitioners continue serving school-age students, thereby supporting results from previous studies. Finally, salaries of O&M practitioners have positively increased over time after accounting for inflation. Implications for Practitioners: Current characteristics of O&M practitioners have implications for recruitment of more diverse young professionals to serve the diversity of those they teach. It is evident the field should try to increase diversity within its ranks to mirror the diverse population they serve. Moreover, O&M salaries have kept pace or exceeded inflation, and thus the profession continues to be attractive in recruiting qualified and diverse professionals.
Conditional Score Approach to Errors‐in‐Variable Current Status Data Under the Proportional Odds Model

Abstract. The conditional score approach is proposed to the analysis of errors‐in‐variable current status data under the proportional odds model. Distinct from the conditional scores in other applications, the proposed conditional score involves a high‐dimensional nuisance parameter, causing challenges in both asymptotic theory and computation. We propose a composite algorithm combining the Newton–Raphson and self‐consistency algorithms for computation and develop an efficient conditional score, analogous to the efficient score from a typical semiparametric likelihood, for building an asymptotic linear expression and hence the asymptotic distribution of the conditional‐score estimator for the regression parameter. Our proposal is shown to perform well in simulation studies and is applied to a zebrafish basal cell carcinoma data involving measurement errors in gene expression levels.
Does Religiosity Matter in Personal Knowledge Management and Job Performance? A Case of Employees in Public Sector in Malaysia

Malaysia is currently in the phase of the Fourth Industrial Revolution (4IR) in which organizations have to deal with Big Data and the value of the technology becomes essential in this respect. In preparing for that, in the current time, our way of life will have to be altered according to the developments that will emerge from this revolution. Based on the 4IR, personal knowledge management becomes the best approach to access Big Data. This is because, during this revolution, employees are no longer able to store and retrieve information via the previous traditional database management system. The revolution of big data in Malaysia also gives a huge impact on employees in the public sector, as they are the backbone of the country and the Big Data is believed to be able to sustain all developments. In this line of discussion comes the purpose of this study which is to examine the relationship between personal knowledge management and employee performance in the selected public organization sector in Shah Alam. Additionally, religiosity takes the role of moderation variable in fulfilling the objectives of the study. The quantitative survey is used to collect the data with a convenient sampling technique being used to collect data from 200 respondents. The finding of this study informed that personal knowledge management is significantly associated with employee performance. Interestingly, the finding also revealed that religiosity moderates the relationship between personal knowledge management and employee performance. The findings suggested that as Islam is governed by the Shariah laws, Muslims are expected to be responsible and careful with everything that they do. As this involves workplace employment too, consequently, work performance in the organization can improve in terms of personal knowledge management whereby they are wise in using the enriched knowledge from big data for their career achievement and more importantly for the success and prosperity of the organization they work in.
Study of Bifenazate, Indoxacarb and Emamectin Benzoate Residues on Tomato

Experiments were conducted on the tomato to study the residues and dissipation rates of bifenazate, indoxacarb, and emamectin benzoate during the summer plantation of 2021 at different intervals (2h), 1, 3, 6, 9, 12, and 15 days. QuEChERS method was used for extraction and clean-up and analyzed using HPLC. Results revealed that the initial amounts of bifenazate, indoxacarb, and emamectin benzoate in leaves and fruits were3.641, 1.463; 2.592, 0.943, and 1.721, 0.215, respectively. Loss percentages in residues were higher in tomato fruits than leaves. The half-life (t½) values of bifenazate, indoxacarb, and emamectin benzoate were 1.86, 2.16; 1.83, 3.01, and 0.973, 1.16 days in tomato fruits and leaves, respectively. No residues were detected in processed tomato paste from contaminated tomato fruits with the tested pesticides indicating 100% removal. Also, washing tomato fruits resulted in a 22.92–42.45, 5.57–21.31, and 15.79–33.02% removal percentage from the residues of bifenazate, indoxacarb, and emamectin benzoate, respectively. Contaminated tomatoes could be consumed safely after 3 days for unwashed and washed fruits contaminated with the three tested pesticides according to the maximum residues limit (MRL) of the EU pesticides database - European Commission.