Miracle-dz/UniFAR-FTUs huggingface dataset:
The effect of endometriosis on live birth rate and other The effect of endometriosis on live birth rate and other reproductive outcomes in ART cycles: a cohort study reproductive outcomes in ART cycles: a cohort study

STUDY QUESTION : What is the effect of endometriosis compared to unexplained subfertility on live birth rate in women undergoing IVF and embryo transfer (ET)? SUMMARY ANSWER : Endometriosis decreases live birth rate in women undergoing IVF-ET treatment, particularly increasing severity of the disease. WHAT of the of a multi-locular cyst with ground-glass appearance and no vascular papillary projections. We did not collect information on the interval between the diagnosis of endometriosis and start of IVF treatment. Those in the non-exposed group were de ﬁ ned as women with con ﬁ rmed ovulatory cycles with mid-luteal progesterone of at least 16 pmol/l, patent Fallopian tubes demonstrable with dye test at laparoscopy and no evidence of endometriosis on laparoscopy, con ﬁ rming a diagnosis of unexplained subfertility. Those with multiple diagnoses, severe male factor subfertility, undergoing donor ART treatment, choosing to freeze embryos or returning for a subsequent cycle were excluded. We also excluded cases of treatment protocols other than the long GnRH agonist.
SELECTION OF COLLISION DETECTION MODEL ON THE BASIS OF A COLLISION OF INCOMPATIBLE VEHICLES

: In today's world, many road users are exposed to the risk of accident. The consequences of the potential crash depend not only on the collision speed, but also on the type of vehicle. The article shows the problems connected with choosing an appropriate collision detection model in the case of a collision of two incompatible vehicles. In addition, directions and values of acceleration of inertia during the crash have been determined and presented. The case study is a collision of a motor car with a combine-harvester in which the problem of incompatibility is particularly noticeable. Simulation calculations were performed using the V-SIM4 code. Experimental verification has demonstrated practical application of a collision detection volumetric model, which best represents the impact of such a vehicle. The article also includes information on how to use the collision detection model in the V-SIM4 code, which may be used by court judges, assessors and investigators, as verification of these collision computers codes for cars is unavailable in the literature. Therefore, the subject of the article is both cognitive and practical.
A nonclassical non-V (cid:1) 14J (cid:1) 18 CD1d-restricted (type II) NKT cell is sufﬁcient for down-regulation of tumor immunosurveillance

The importance of immunoregulatory T cells has become increasingly apparent. Both CD4 (cid:1) CD25 (cid:1) T cells and CD1d-restricted NKT cells have been reported to down-regulate tumor immunity in mouse tumor models. However, the relative roles of both T cell populations have rarely been clearly distinguished in the same tumor models. In addition, CD1d-restricted NKT cells have been reported to play a critical role not only in the down-regulation of tumor immunity but also in the promotion of the immunity. However, the explanation for these apparently opposite roles in different tumor models remains unclear. We show that in four mouse tumor models in which CD1d-restricted NKT cells play a role in suppression of tumor immunity, depletion of CD4 (cid:1) CD25 (cid:1) T cells did not
QTL for Pubertal and Seasonality Traits in Male Pe`re David’s (cid:1) Red Deer Interspecies Hybrids

The unique Pe`re David’s ( Elaphurus davidianus ) (cid:1) red deer ( Cervus elaphus ) backcross hybrid has been used to search for evidence of quantitative trait loci (QTL) for antler pubertal (date and live weight at pedicle initiation) and antler seasonality (date of antler cleaning and casting) traits in temperate species of deer. Analyses using marker information revealed evidence for a QTL for date at pedicle initiation (LOD (cid:2) 3.7) and live weight at pedicle initiation (LOD (cid:2) 3.1). These QTL explained 13% and 11% of the phenotypic variance in these traits, respectively. The January tetra ( Hemigrammus hyanuary Durbin) exhibits two eye color phenotypes. These have a silver iris, which is characteristic of the species, and a green color variant. Segregation patterns observed in the progenies from 12 different crosses support an hypothesis for the monogenic inheritance of iris coloration in this species.
BANYAN. VII. A NEW POPULATION OF YOUNG SUBSTELLAR CANDIDATE MEMBERS OF NEARBY MOVING GROUPS FROM THE BASS SURVEY

We present the results of a near-infrared (NIR) spectroscopic follow-up survey of 182 M4–L7 low-mass stars and brown dwarfs (BDs) from the BANYAN All-Sky Survey (BASS) for candidate members of nearby, young moving groups (YMGs). We confirm signs of low gravity for 42 new BD discoveries with estimated masses between 8 and 75 M Jup ? > and identify previously unrecognized signs of low gravity for 24 known BDs. We refine the fraction of low-gravity dwarfs in the high-probability BASS sample to ∼82%. We use this unique sample of 66 young BDs, supplemented with 22 young BDs from the literature, to construct new empirical NIR absolute magnitude and color sequences for low-gravity BDs. We show that low-resolution NIR spectroscopy alone cannot differentiate between the ages of YMGs younger than ∼120 Myr, and that the BT-Settl atmosphere models do not reproduce well the dust clouds in field or low-gravity L-type dwarfs. We obtain a spectroscopic confirmation of low gravity for 2MASS J14252798–3650229, which is a new ∼27 M Jup ? > , L4 γ bona fide member of AB Doradus. We identify a total of 19 new low-gravity candidate members of YMGs with estimated masses below 13 M Jup ? > , 7 of which have kinematically estimated distances within 40 pc. These objects will be valuable benchmarks for a detailed atmospheric characterization of planetary-mass objects with the next generation of instruments. We find 16 strong candidate members of the Tucana–Horologium association with estimated masses between 12.5 and 14 M Jup ? > , a regime where our study was particularly sensitive. This would indicate that for this association there is at least one isolated object in this mass range for every 17.5 − 5.0 + 6.6 ? > main-sequence stellar member, a number significantly higher than expected based on standard log-normal initial mass function, however, in the absence of radial velocity and parallax measurements for all of them, it is likely that this over-density is caused by a number of young interlopers from other associations.
Bacteriological Quality and Antibiogram of Isolates from Potable Water Sources in Community,

: This study sought to determine the bacteriological quality of some boreholes and storage tanks used for drinking and other domestic purposes in Ekosodin community and evaluated the antimicrobial susceptibility patterns of the groundwater resources isolates. A total of 48 samples were collected from three boreholes and storage tanks for a period of two months. Samples were analyzedfor microbiological content following standard procedures. Feacal Coliform (FC) and Feacal Streptoccocci (FS) counts and antimicrobial susceptibility patterns were evaluated using the Most Probable Number and Kirby-Bauer methods respectively.The mean FC counts (1.2±0.3Cfu/100ml -55±10Cfu/100ml) and meanSF counts (0cfu/100ml – 9.25±1.1Cfu/100ml) in some of the samples examined, exceeded the WHO limit of 0Cfu/100ml for drinking water. Significant differences were recorded for mean FS counts betweensome boreholes and storage tanks. Escherichia coli (34%), Klebsiella sp (23%), Pseudomonas sp (19%) and Feacal Streptococci (12%) were amongst the identified isolates from the water samples. The antibiogram analysis revealed that all isolates (87%) except some strains of Feacal Streptococci were sensitive to ciprofloxacin and 73% of isolates were resistant to Erythromycin. All isolates exhibited a multi drug resistance to at least eight antibiotics. The microbial analysis revealed a faecal contamination of the groundwater, making it unfit for drinking without proper disinfection.
Identiﬁcation of in vitro growth conditions for c-Kit–negative hematopoietic stem cells

Our laboratory recently identiﬁed a quies-cent class of pluripotent hematopoietic stem cells (PHSCs) that are lineage negative (Lin neg ), lack c-Kit, and are able to give rise to c-Kit–positive (c-Kit pos ) PHSCs in vivo. This population fails to proliferate in vitro but has delayed reconstituting activity in vivo. In this study, we puriﬁed these cells to enrich for the PHSCs and we identiﬁed in vitro conditions capable of supporting their maturation. The c-Kit– negative (c-Kit neg ) cells exhibited differential expression of Sca-1, CD34, CD43, CD45, and Thy 1.2. We puriﬁed the cells based on Sca-1, as it is expressed on active PHSCs. We detected pre–colony-forming unit spleen (pre–CFU-s) activity in both the Sca-1 neg and Sca-1 pos populations, indicating the presence of primitive PHSCs in both populations. However, our in vitro studies suggest that the Sca-1 pos population is enriched for PHSCs. The in vitro systems that support the growth of these dormant cells include a modiﬁed long-term marrow culture and various stromal cell lines. In modiﬁed long-term bone marrow cultures, c-Kit neg cells gave rise to c-Kit pos PHSCs, with long-term reconstitution activity in vivo. Thus we have established an in vitro system to examine PHSC maturation that will allow us to study the mediators of the c-Kit neg to c-Kit pos transition. (Blood. 2003;102: 3120-3128) ©
Implementation of Lean-Kaizen in Saudi Arabian Higher Education Sector

: The Lean-Kaizen has been utilized in different sectors over the past years as a continuous improvement tool and wastes elimination to gain competitive advantage. Indeed, Lean- Kaizen implementation in the higher education sector has not been employed effectively in some countries. The paper aims to examine the current status of Lean-Kaizen implementation in the Saudi Arabian higher education sector. The survey was distributed to several universities in Saudi Arabia and the findings of the survey illustrated that the implementation of Lean-Kaizen is still in the early stages and not adopted widely in universities within Saudi Arabia. The paper provides valuable information about the current status of the Lean - Kaizen implementation in the Saudi Arabian higher education sector. A recommendation was proposed to guide universities and practitioners for future continuous improvement efforts.
Effect of 30 Minutes Brisk Walking on Hemoglobin Concentration and Leukocyte Count

Walking is an isotonic exercise and has been associated with physiological changes in many systems including hematological system. The aim of this study was to examine acute changes in some of the blood parameters after a 30 min of brisk walk in fifty young healthy subjects of Chitwan, Nepal. The venous blood samples were drawn before & after 30 minutes of brisk walking. Estimation of hemoglobin concentration, total leukocyte count and differential leukocyte count was determined. Statistical data was analyzed using SPSS software version 20. Dependent t-test was used to compare the means before and after the walk. The study demonstrated that brisk walk for even 30 minutes has some positive influence on blood parameters. Hemoglobin concentration, Leukocyte count, Neutrophil percentage were increased significantly (p<0.05) while lymphocyte was decreased. It was concluded that brisk walking is also physiological stress to body which is healthy and also leads to improvement in hemodynamic status.
Non-linear pulsations in Wolf-Rayet stars

Numerical simulations of the evolution of strange-mode instabilities into the non-linear regime have been performed for a wide range of stellar parameters for Wolf-Rayet stars. It has been shown that the Wolf-Rayet models reach radial velocities which amount to up to 30% of their escape velocity. The acoustic luminosities suggest a connection to the observed mass loss. Most of the models show a jump in the mean effective temperature after reaching the non-linear regime. This jump is related to the run of the opacity.
Elementary Principles in Statistical Mechanics: Developed with Especial Reference to the Rational Foundation of Thermodynamics

Preface 1. General notions. The principle of conservation of extension-in-phase 2. Application of the principle of conservation of extension-in-phase to the theory of errors 3. Application of the principle of conservation of extension-in-phase to the integration of the differential equations of motion 4. On the distribution-in-phase called canonical, in which the index of probability is a linear function of the energy 5. Average values in a canonical ensemble of systems 6. Extension-in-configuration and extension-in-velocity 7. Farther discussion of averages in a canonical ensemble of systems 8. On certain important functions of the energies of a system 9. The function PHI and the canonical distribution 10. On a distribution in phase called microcanonical in which all the systems have the same energy 11. Maximum and minimum properties of various distributions in phase 12. On the motion of systems and ensembles of systems through long periods of time 13. Effect of various processes on an ensemble of systems 14. Discussion of thermodynamic analogies 15. Systems composed of molecules.
Risk Behaviour and Attachment of Adolescents in Lower Secondary Education in Slovakia

– In this paper we focused on the relation between the attachment of the adolescents and the risk behaviour production . In the research we worked with 220 adolescents in the lower secondary education system, average age 12.32 years. We applied two research methods: IPPA-R (Inventory of Parent and Peer Attachment – Revised; Greenberg, Armsden, 1987), QRB (Questionnaire of Risk Behaviour; Čerešník, 2016). In general, we assumed that the higher risk behaviour production of the adolescents with worse relation with the parents and the peers, the lower is the level of attachment. The results showed that this assumption can be supported.
DDDT_A_288841 1749..1763

1Department of Neurosurgery, Henan Provincial People’s Hospital, Central China Fuwai Hospital, Central China Fuwai Hospital of Zhengzhou University, Zhengzhou, People’s Republic of China; 2Department of Neurosurgery, The Second Affiliated Hospital of Air Force Military Medical University, Xi’an City, People’s Republic of China Background: The role of Hydroxysafflor Yellow A (HSYA) in glioma is less studied, this research determined the effect of HSYA on glioma cells. Methods: The expressions of MYC and NBS1 in glioma tissues were detected by bioinformatics analysis and verified by RT-qPCR. The target relationship between MYC and NBS1 was predicted by bioinformatics. After treating the cells with HSYA, silenced MYC, or overexpressed NBS1, the viability, apoptosis, proliferation, invasion, migration, and DNA damage of the glioma cells were detected by MTT, flow cytometry, colony formation, transwell, wound healing, and γH2AX immunofluorescence assays, respectively. IC50 of HSYA in glioma cells was analyzed by Probit regression analysis. The expressions of MYC, NBS1, factors related to migration, invasion, apoptosis, and DNA damage of the glioma cells were determined by Western blot or RT-qPCR. Results: MYC and NBS1 were high-expressed in glioma, and NBS1 was targeted by MYC. HSYA and siRNA targeting MYC inhibited the cell viability, proliferation, invasion, migration, and induced the cell apoptosis of glioma cells. HSYA upregulated the expressions of MYC, γH2AX, E-Cadherin, Bax, and Cleaved-PARP1, stimulated the activation of NBS1, MRE11, RAD50, and ATM, and downregulated the expressions of N-Cadherin and Bcl2 in glioma cells. SiMYC decreased the IC50 of HSYA in the glioma cells, enhanced the sensitivity of glioma cells to HSYA, and inhibited the activation of NBS1 and ATM. NBS1 overexpression reversed the effect of siRNA targeting MYC on glioma cells. Conclusion: MYC silencing inhibited the DNA damage response via regulation of NBS1, leading to DNA repair deficiency, and subsequently enhanced the sensitivity of glioma cells to HSYA.
Francisella tularensis T-Cell Antigen Identiﬁcation Using Humanized HLA-DR4 Transgenic Mice (cid:1)

There is no licensed vaccine against the intracellular pathogen Francisella tularensis. The use of conventional mouse strains to screen protective vaccine antigens may be problematic, given the differences in the major histocompatibility complex (MHC) binding properties between murine and human antigen-presenting cells. We used engineered humanized mice that lack endogenous MHC class II alleles but that express a human HLA allele (HLA-DR4 transgenic [tg] mice) to identify potential subunit vaccine candidates. Speciﬁcally, we applied a biochemical and immunological screening approach with bioinformatics to select putative F. tularensis subsp. novicida T-cell-reactive antigens using humanized HLA-DR4 tg mice. Cell wall- and membrane-associated proteins were extracted with Triton X-114 detergent and were separated by fractionation with a Rotofor apparatus and whole-gel elution. A series of proteins were identiﬁed from fractions that stimulated antigen-speciﬁc gamma interferon (IFN- (cid:1) ) production, and these were further downselected by the use of bioinformatics and HLA-DR4 binding algorithms. We further examined the validity of this combinatorial approach with one of the identiﬁed proteins, a 19-kDa Francisella tularensis a expressing (DRB1*0401) functioning antigen-presenting cells. Intranasal immunization of HLA-DR4 tg mice with the single antigen FopB conferred signiﬁcant protection against lethal pulmonary challenge with an F. tularensis subsp. holarctica live vaccine strain. These results demonstrate the value of combining functional biochemical and immunological screening with humanized HLA-DR4 tg mice to map HLA-DR4-restricted Francisella CD4 (cid:2) T-cell epitopes.
2 : Boosted AGN and star formation activity in CIZA a massive post-merger cluster at z = 0.19

Cluster mergers may play a fundamental role in the formation and evolution of cluster galaxies. Stroe et al. (2014) revealed unexpected over-densities of candidate H α emitters near the ∼ 1 Mpc-wide shock fronts of the massive ( ∼ 2 × 10 15 M (cid:12) ) “Sausage” merging cluster, CIZA J2242.8+5301. We used Keck/DEIMOS and WHT/AF2 to conﬁrm 83 H α emitters in and around the merging cluster. We ﬁnd that cluster star-forming galaxies in the hottest X-ray gas and/or in the cluster sub-cores (away from the shock fronts) show high [S II ] 6716/[S II ] 6761 and high [S II ] 6716/H α , implying very low electron densities ( < 30 × lower than all other star-forming galaxies outside the cluster) and signiﬁcant contribution from supernovae, re-spectively. All cluster star-forming galaxies near the cluster centre show evidence of significant outﬂows (blueshifted Na D ∼ 200 − 300 km s − 1 ), likely driven by supernovae. Strong outﬂows are also found for the cluster H α AGN. H α star-forming galaxies in the merging cluster follow the z ∼ 0 mass-metallicity relation, showing systematically higher metallicity ( ∼ 0.15-0.2 dex) than H α emitters outside the cluster (projected R > 2 . 5 Mpc). This suggests that the shock front may have triggered remaining metal-rich gas which galaxies were able to retain into forming stars. Our observations show that the merger of impressively massive ( ∼ 10 15 M (cid:12) ) clusters can provide the conditions for signiﬁcant star-formation and AGN activity, but, as we witness strong feedback by star-forming galaxies and AGN (and given how massive the merging cluster is), such sources will likely quench in a few 100 Myrs.
OPTH_A_331700 3939..3945

1Research Department, King Khaled Eye Specialist Hospital, Riyadh, Saudi Arabia; 2Department of Ophthalmology, Prince Sultan Medical Military City, Riyadh, Saudi Arabia; 3Vitreoretinal Division, King Khaled Eye Specialist Hospital, Riyadh, Saudi Arabia; 4Department of Translational Medicine, University of Ferrara, Ferrara, Italy; 5Department of Ophthalmology, Clinical Sciences, Skane County University Hospital, Lund University, Lund, Sweden
Global Gene Expression Patterns of Nostoc punctiforme in Steady-State Dinitrogen-Grown Heterocyst-Containing Cultures and at Single Time Points during the Differentiation of Akinetes and Hormogonia (cid:1) †

The vegetative cells of the ﬁlamentous cyanobacterium Nostoc punctiforme can differentiate into three mutually exclusive cell types: nitrogen-ﬁxing heterocysts, spore-like akinetes, and motile hormogomium ﬁla- ments. A DNA microarray consisting of 6,893 N . punctiforme genes was used to identify the global transcription patterns at single time points in the three developmental states, compared to those in ammonium-grown time zero cultures. Analysis of ammonium-grown cultures yielded a transcriptome of 2,935 genes, which is nearly twice the size of a soluble proteome. The NH 4 (cid:1) -grown transcriptome was enriched in genes encoding core metabolic functions. A steady-state N 2 -grown (heterocyst-containing) culture showed differential transcription of 495 genes, 373 of which were up-regulated. The majority of the up-regulated genes were predicted from studies of heterocyst differentiation and N 2 ﬁxation; other genes are candidates for more detailed genetic analysis. Three days into the developmental process, akinetes showed a similar number of differentially expressed genes (497 genes), which were equally up- and down-regulated. The down-regulated genes were enriched in core metabolic functions, consistent with entry into a nongrowth state. There were relatively few adaptive genes up-regulated
Towards End-to-End Learning of Monocular Visual-Inertial Odometry with an Extended Kalman Filter

Towards End-to-End Learning of Monocular Visual-Inertial Odometry with an Extended Kalman Filter Chunshang Li Master of Applied Science Graduate Department of University of Toronto Institute for Aerospace Studies University of Toronto 2020 Classical visual-inertial fusion relies heavily on manually crafted image processing pipelines, which are prone to failure in situations with rapid motion and texture-less scenes. While end-to-end learning methods show promising results in addressing these limitations, embedding domain knowledge in the form of classical estimation processes within the endto-end learning architecture has the potential of combining the best of both worlds. In this thesis, we propose the first end-to-end trainable visual-inertial odometry (VIO) algorithm that leverages a robo-centric Extended Kalman Filter (EKF). The EKF propagates states through a known inertial measurement unit (IMU) kinematics model and accepts relative pose measurements and uncertainties from a deep network as updates. The system is fully differentiable and can be trained end-to-end through backpropagation. Our method achieves competitive results among state of the art classical and learning based VIO methods on the KITTI dataset.
Convergence of the Relative Pareto Eﬃcient Sets

The aim of this paper is to present new results on the convergence of relative Pareto eﬃcient sets and the lower semicontinuity of relative Pareto eﬃcient point multifunctions under perturbations. Our results extend some results of Luc et al. [16, Theorem 2.1], Bednarczuk [4, Theorem 4] and [5, Proposition 3.1], Lucchetti and Miglierina [17, Proposition 3.1]. Some remarks and examples are provided for analysing the results obtained and for comparing them with the preceding results.