Miracle-dz/UniFAR-FTUs huggingface dataset:
Influence of Language Coaching Techniques on Undergraduate Students’ Motivation in the Process of Foreign Languages Teaching at Non-linguistic Specialties

The application of coaching techniques is popular in the worldwide practice of specialist training and is used in various fields. However, the problem of introduction of coaching technniques in foreign languages learning in Ukraine remains insufficiently covered and requires a more detailed study. This paper aimed to study the influence of language coaching techniques (LCT) on undergraduate students’ motivation in the process of foreign language teaching at non-linguistic specialties. The study sought to answer the main research questions: 1.What effect would LCT have on undergraduate students’ motivation to learn foreign languages at Ternopil Volodymyr Hnatiuk National Pedagogical University (TNPU) in Ukraine? 2. How will the students perceive LCT while learning languages? The research employs qualitative methods (scientific observations, analysis of student activity results) to substantiate research theoretical grounds; quantitative metods (testing and self-assessment reviews) to identify the efficacy of LCT, communicative methods (conversations, discussions), and methods of mathematical analysis to do calculations of the collected research data. The conducted experiment involved randomly chosen 62 second-year students of the first (bachelor) higher education level of non-linguistic specialties of TNPU. The study concluded that the applied LCT at foreign language classes during the experiment provided positive dynamics in the growth of students’ motivation to knowledge acquisition. The findings would have practical significance for teachers of foreign languages who want to organize the learning process and make it more effective.
Pseudo-multiplicative unitaries on C*-modules and Hopf C*-families I

Pseudo-multiplicative unitaries on C*-modules generalize the multiplicative unitaries of Baaj and Skandalis [1], and are analogues of the pseudo-multiplicative unitaries on Hilbert spaces studied by Enock, Lesieur, Vallin [5], [10], [21]. We introduce Hopf C*-families on C*-bimodules and associate to special classes of pseudo-multiplicative unitaries two Hopf C*-families. Furthermore, we discuss dual pairings and counits on these Hopf C*-families, etale and proper pseudo-multiplicative unitaries, and two classes of examples. In a later article, we will study regularity conditions on pseudo-multiplicative unitaries, coactions of Hopf C*-families on C*-algebras, and duality. Mathematics Subject Classification (2000). 46L55; 46L08, 22A22, 46L05.
Effect of Vacuum Packaging on the Biochemical, Viscoelastic, and Sensory Properties of a Spanish Cheese during Chilled Storage

The unique qualities of Spanish cheeses, such as the San Simón da Costa (SSC) cheese, are protected by the Protected Designation of Origin (PDO) status. The technological importance of chilled storage at 4 °C of vacuum-packaged (V) and natural (N) (unpackaged) cheeses was examined. For this purpose, the physico-chemical, biochemical, mechanical (puncture tests), viscoelastic (oscillatory and transient tests) and sensory properties of V and N cheeses were compared and analysed. During chilled storage, the caseins in V cheeses did not undergo proteolytic reactions. Low temperature maintained a low intensity of proteolytic phenomena for up to 6 months. Lipolysis was more intense in the N than in the V samples. The moisture content decreased in the N cheeses during chilled storage, and thus, the casein matrix concentration and ionic strength increased, resulting in an increase in the gel strength (S) parameter and complex modulus (G*), and the conformational stability−high stress amplitude (σmax). The low and similar values of the n’ and n’’ exponents (mechanical spectra) and the n parameter (transient tests) indicated the high degree of the temporal stability of the cheese network in both the N and V samples, irrespective of storage time. Likewise, the similar values of the phase angle (δ) for the N and V cheeses during storage indicate energy-stable bonds in the SSC cheese matrix. The attributes of the oral tactile phase (firmness, friability, gumminess, and microstructure perception), mechanical parameters and viscoelastic moduli enabled the discrimination of the packaged and unpackaged cheeses. Cheeses chilled and stored without packaging were awarded the highest scores for sensory attributes (preference) by trained panellists.
Theoretical prediction of GaN nanostructure equilibrium and nonequilibrium shapes

A wide variety of nanostructure shapes have been observed for GaN under different growth conditions. These shapes include but are not limited to hexagonal pyramid, prismatic, triangular cross-section nanowires, and arrow-headed shapes. Using Wulff’s plot and kinetic Wulff’s plot for GaN under thermodynamic equilibrium and under various kinetic conditions, we present a model to theoretically predict and explain these faceted nanostructure shapes. Legendre transformation on Wulff’s plot and kinetic Wulff’s plot has been extensively utilized to obtain the faceted equilibrium shapes in equilibrium. In addition, equilibrium and nonequilibrium faceted geometry of nanostructures have also been predicted by numerical simulations using level set methods and the proposed kinetic Wulff’s plot.
Wind Anisotropy and Angular Momentum Loss in a Massive Rotating Binary System

The model of anisotropic loss of the mass and angular momentum is constructed and the non-conservative evolution of the binary system is investigated in this paper. The joint effects of the centrifugal force and tidal force cause the configurations of two components to become triaxial ellipsoids. The high-order disturbing potential, which includes the rotational and tidal distortions, is applied to describe the local gravity in a close binary system. The geff (� , ')-effect dominates the mass-loss distribution in the massive O-type star. Both the geff(� , ')-effect and the � -effect have an important influence on the equatorial ejection, and the Roche lobe overflow and the H-shell burning occur earlier in the rotational models. The rotation and tide can intensify the mass loss before mass overflow, and the rate of stellar wind goes down, resulting from a decrease of the luminosity in the subsequent stages. The highorder disturbing potential and other associated physical factors may significantly affect the Roche lobe and might be possible to drive the non-conservative mass transfer process when the stars approach the break-up rotation. Rotation and tide can allow the primary to shift towards the blue side of the HR diagram and modify the thermal relaxation time-scale in the slow phase of the mass transfer in Case A. The star attempts to attain thermal equilibrium and displays a slightly cyclical expansion and contraction. When stellar wind was taken into consideration in the model, the secondary star accreted less mass than the model without stellar wind.
The Effects of Moxifloxacin and Gemifloxacin on the ECG Morphology in Healthy Volunteers: A Phase 1 Randomized Clinical Trial

Moxifloxacin and gemifloxacin are the two newer broad-spectrum 8-methoxy-quinolone derivatives that are used to treat various bacterial infections in cardiac patients. In this research study, we assessed the impact of moxifloxacin and gemifloxacin on the QT intervals of electrocardiograms in normal adult doses and draw a comparison, in a controlled environment, on healthy volunteers. Additionally, the effect of both test drugs on the QRS complex was checked. Sixty healthy volunteers were randomly assigned to two groups via R-software, and each respectively received moxifloxacin and gemifloxacin for five days. The research ethics committee approved the research, and it was registered for clinical trial under NCT 04692623. The participants’ electrocardiograms were obtained before the start of the dose (baseline) and on the fifth day. Significant prolongation of QT interval was noted in moxifloxacin (p < 0.0001) as compared to gemifloxacin treated groups. There were no cases of QTc prolongation over the usual limits (450–470 ms) in the gemifloxacin-treated group, however, QTc prolongations at the rate of 30 and 60 ms from the baseline were noted, interpreted as per the EMEA guidelines. These findings indicate that moxifloxacin caused significant (p < 0.0001) QT interval prolongation (QTIP) as compared to gemifloxacin. In contrast to the previously reported literature, the prominent effect of moxifloxacin on the widening of the QRS-complex was noted with no such effect on QRS-widening in the gemifloxacin-treated group. It is concluded that both drugs have the potential for considerable QT interval prolongation (QTIP) effects, which is one of the risk factors for developing torsade de pointes (TdPs) in cardiac patients. Thus, clinicians should exercise caution when prescribing moxifloxacin and gemifloxacin to cardiac patients and should consider alternate treatment options.
Chemical Space Virtual Screening against Hard-to-Drug RNA Methyltransferases DNMT2 and NSUN6

Targeting RNA methyltransferases with small molecules as inhibitors or tool compounds is an emerging field of interest in epitranscriptomics and medicinal chemistry. For two challenging RNA methyltransferases that introduce the 5-methylcytosine (m5C) modification in different tRNAs, namely DNMT2 and NSUN6, an ultra-large commercially available chemical space was virtually screened by physicochemical property filtering, molecular docking, and clustering to identify new ligands for those enzymes. Novel chemotypes binding to DNMT2 and NSUN6 with affinities down to KD,app = 37 µM and KD,app = 12 µM, respectively, were identified using a microscale thermophoresis (MST) binding assay. These compounds represent the first molecules with a distinct structure from the cofactor SAM and have the potential to be developed into activity-based probes for these enzymes. Additionally, the challenges and strategies of chemical space docking screens with special emphasis on library focusing and diversification are discussed.
Sex-Specific Models to Predict Insulin Secretion and Sensitivity in Subjects with Overweight and Obesity

Sex-specific differences exist in insulin secretion (ISec) and sensitivity (IS) in humans. However, current fasting indices used to estimate them, such as HOMA and QUICKI, are not sex-specific. We aimed to develop sex-specific models to improve the prediction of ISec and IS by fasting measures in adults with overweight/obesity. A post hoc analysis was conducted on baseline data of two clinical trials completed between 2010 and 2020 (37 men and 61 postmenopausal women, 45–73 years, BMI > 25 kg/m2, without chronic disease). Glucose-induced insulin or C-peptide secretions and IS were measured using gold-standard Botnia-clamps, which is a 1 h intravenous glucose tolerance test followed by a 3 h hyperinsulinemic–euglycemic clamp. Stepwise regression analysis using anthropometric and fasting plasma glucose, insulin, and lipoprotein-related measures was used to predict ISec and IS. First-phase, second-phase and total glucose-induced ISec were predicted by a combination of fasting plasma insulin and apoB without or with plasma glucose, triglyceride, and waist circumference in women (R2 = 0.58–0.69), and by plasma insulin and glucose without or with BMI and cholesterol in men (R2 = 0.41–0.83). Plasma C-peptide, alone in men or followed by glucose in women, predicted C-peptide secretion. IS was predicted by plasma insulin and waist circumference, followed by HDL-C in women (R2 = 0.57) or by glucose in men (R2 = 0.67). The sex-specific models agreed with the Botnia-clamp measurements of ISec and IS more than with HOMA or QUICKI. Sex-specific models incorporating anthropometric and lipoprotein-related parameters allowed better prediction of ISec and IS in subjects with overweight or obesity than current indices that rely on glucose and insulin alone.
Seroprevalence of Anti-Echinococcus granulosus Antibodies and Risk Factors for Infection in Blood Donors from Western Romania

Cystic echinococcosis is a worldwide-distributed zoonotic parasitic disease. This cross-sectional study aimed to assess the seroprevalence and risk factors potentially associated with Echinococcus granulosus in healthy blood donors from Timis County, an endemic region in Western Romania. Serum samples were collected from 1347 Romanian blood donors. Serologic tests to determine the presence of anti-Echinococcus antibodies were performed using an anti-Echinococcus-ELISA immunoassay. Anti-Echinococcus antibodies were detected in 38 blood donors, indicating an overall seroprevalence of 2.8%. The seropositivity rate was 3.7% in females and 3.1% in blood donors residing in urban areas. The highest seropositivity was found in the age group of 31–40 years (3.6%). There were no significant differences between Echinococcus seropositivity and gender, area of residence, age, contact with dogs, or raising sheep. This serologic survey evaluated for the first time the presence of Echinococcus antibodies in healthy blood donors from Western Romania and the potential risk factors associated with echinococcosis. Our results suggest that this zoonotic infection might evolve asymptomatically in apparently healthy individuals. Further studies should be conducted in the general population to estimate the true extent of human echinococcosis and its risk factors.
Prime Labeling Of Friendship Graphs

K. Vaithilingam Associate Professor of Maths Govt. Arts College, C.Mutlur-608 102 Chidambaram. Abstract: A graph with vertex set V is said to have a prime labeling if its vertices are labeled with distinct integer 1,2,3. V such that for edge xy the labels assigned to x and y are relatively prime. A graph which admits prime labeling is called a prime graph. In this paper we investigate prime labeling for some fan related graphs. We also discuss prime labeling in the context of some graph operations namely fusion and duplication in fan Fn
Limits on the space density of gamma-ray burst sources

Gamma-ray burst spectra which extend to several MeV without significant steepening indicate that there is negligible degradation due to two-photon pair production. The inferred low rate of photon-photon reactions is used to give upper limits to the distances to the sources and to the intensity of the radiation from the sources. These limits are calculated under the assumptions that the bursters are neutron stars which emit uncollimated gamma rays. The principal results are that the space density of the gamma-ray burst sources exceeds approx.10 W pc T if the entire surface of the neutron star radiates and exceeds approx.10 T pc T if only a small cap or thin strip in the stellar surface radiates. In the former case the density of gamma-ray bursters is approx.1% of the inferred density of extinct pulsars, and in the latter case the mean mass density of burster sources is a few percent of the density of unidentified dark matter in the solar neighborhood. In both cases the X-ray intensity of the sources is far below the Rayleigh-Jeans limit, and the total flux is at most comparable to the Eddington limit. This implies that low-energy self-absorption near 10 keV is entirely negligible and thatmore » radiation-driven explosions are just barely possible. « less
Sonographic and Magnetic Resonance Characteristics of Gynecological Sarcoma

Introduction: Gynecological sarcomas are rare malignant tumors with an incidence of 1.5–3/100,000 and are 3–9% of all malignant uterine tumors. The preoperative differentiation between sarcoma and myoma becomes increasingly important with the development of minimally invasive treatments for myomas, as this means undertreatment for sarcoma. There are currently no reliable laboratory tests or imaging-characteristics to detect sarcomas. The objective of this article is to gain an overview of sarcoma US/MRI characteristics and assess their accuracy for preoperative diagnosis. Methods: A systematic literature review was performed and 12 studies on ultrasound and 21 studies on MRI were included. Results: For the ultrasound, these key features were gathered: solid tumor > 8 cm, unsharp borders, heterogeneous echogenicity, no acoustic shadowing, rich vascularization, and cystic changes within. For the MRI, these key features were gathered: irregular borders; heterogeneous; high signal on T2WI intensity; and hemorrhagic and necrotic changes, with central non-enhancement, hyperintensity on DWI, and low values for ADC. Conclusions: These features are supported by the current literature. In retrospective analyses, the ultrasound did not show a sufficient accuracy for diagnosing sarcoma preoperatively and could also not differentiate between the different subtypes. The MRI showed mixed results: various studies achieved high sensitivities in their analysis, when combining multiple characteristics. Overall, these findings need further verification in prospective studies with larger study populations.
Spatial statistics: Marks, maps, and shapes

ABSTRACT Spatial statistics is concerned with phenomena unfolding in space and possibly also evolving in time, expressing a system of interactions whereby an observation made at a (spatiotemporal) location is informative about observations made at other locations. In general, the interactions are best described probabilistically, rather than deterministically. Spatial scales range from the microscopic (for example, when describing interactions between molecules of a liquid) to planetary (for example, when studying the Earth’s ozone layer) or even larger; temporal scales are similarly varied. Marks indicate objects whose spatial locations are influenced by the presence and nature of other objects nearby: trees of the same or different species in a grove, molecules in a liquid, or galaxies throughout the universe. The statistical models are (marked) spatial point processes. Maps describe the variability of the values of a property across a geographical region. The Ising model of ferromagnetism describes collective properties of atoms arranged in a regular lattice. When mapping the prevalence or the incidence of a disease at the level of counties or parishes, the observations are associated with subsets of a region whose spatial relations are meaningful. Many maps are drawn based on observations made at a finite set of locations distributed either regularly or irregularly throughout a 2D or 3D spatial domain. For example, the mass fraction of uranium in soils and surface sediments across Colorado. Gaussian random functions are a model of choice for such quantities, possibly after re-expression. Shapes arise owing to modulated interactions between surface elements anchored to points in space — “generators” in the nomenclature of Ulf Grenander’s pattern theory. Probability distributions on spaces of generators and on spaces of interactions between them can then be used to describe variations on patterns and to fit shape models.
Transient deformation and drag of decelerating drops in axisymmetric flows

Transient deformation and drag coefficients of decelerating drops in axisymmetric flows are numerically computed. The drag coefficients are compared with those of solid spheres. In the case of drops, the behavior of the drag coefficient is dependent on the deformation and internal circulation of the drops in addition to the factors which are important for solid spheres. These, in turn, are dependent on the gas-based Weber number (Weg) and the Ohnesorge number (Ohl). At the relatively low Weg of 1, when the deformation is small, the drag coefficients are about the same for the solid sphere and drop. When Weg is increased, the deformation increases and the difference increases. At the highest Weg of 100, the drop reaches a point of secondary breakup. In general, oblate shapes result in greater drag and prolate shapes in lower drag relative to the solid sphere. Increasing Ohl, which implies increasing viscous forces in the liquid relative to surface tension forces, leads to less deformation and hence lesser .
Evaluation of Molecular Methods to Identify Chagas Disease and Leishmaniasis in Blood Donation Candidates in Two Brazilian Centers

In Brazil, blood donation is regulated by the Brazilian Ministry of Health, and all States follow the same protocol for clinical and laboratory screening. Brazil is an endemic country for Chagas disease (CD), caused by Trypanosoma cruzi, and for leishmaniasis, caused by a species of Leishmania spp. Screening for leishmaniosis is not routinely performed by blood banks. Given the antigenic similarity between T. cruzi and Leishmania spp. , cross-reactions in serological tests can occur, and inconclusive results for CD have been found. The objective of this study was to apply molecular techniques, e.g., nPCR, PCR, and qPCR, to clarify cases of blood donation candidates with non-negative serology for CD and to analyze the difference between the melting temperature during real-time PCR using SYBR Green. Thirty-seven cases that showed non-negative results for CD using chemiluminescent microparticle immunoassay (CMIA) tests from blood banks in Campo Grande, MS, and Campinas, SP, were analyzed. In the serum samples, 35 samples were evaluated by ELISA, and 24.3% (9/35) showed positive results for CD. nPCR was able to detect 12 positive results in 35 samples (34.28%). qPCR for T. cruzi was quantifiable in the samples that showed a value ≥0.002 par eq/mL (parasite equivalents per milliliter), and in 35 samples, 11 (31.42%) were positive. Of all evaluated samples using the described tests (CMIA, ELISA, nPCR, and qPCR), 18 (48.6%) were positive for CD. For MCA by qPCR, the melting temperature was 82.06 °C ± 0.46 for T. cruzi and 81.9 °C ± 0.24 for Leishmania infantum. The Mann–Whitney test showed a significant value of p < 0.0001. However, the differentiation between T. cruzi and L. infantum could not be considered due to temperature overlap. For leishmaniasis, of the 35 samples with non-negative serology for CD tested by the indirect fluorescent antibody test (IFAT), only one sample (2.85%) was positive (1:80). The PCR for Leishmania spp. was performed on 36 blood samples from donation candidates, and all were negative. qPCR for L. infantum showed 37 negative results for the 37 analyzed samples. The data presented here show the importance of performing two different tests in CD screening at blood banks. Molecular tests should be used for confirmation, thereby improving the blood donation system.