Miracle-dz/UniFAR-FTUs huggingface dataset:
Practical quantum synchronization for the Schrödinger–Lohe system

We present a practical synchronization method for the Schrödinger–Lohe (S–L) system distinct potentials. The S–L model describes the spatial-temporal evolution of the wave functions of quantum Lohe oscillators on a network with Lohe couplings. When the potential effects are ignored, complete wave function synchronization (CWFS) can emerge in the sense that the L2-distance between wave functions exponentially approaches zero for a class of initial wave functions. In contrast, when the Lohe oscillators are under the effect of potential forces, CWFS cannot occur. In this study, we employ a weaker concept of quantum synchronization for discussing the asymptotic collective behavior of the S–L model. This concept leads to ‘practical synchronization’ of the S–L model. In practical synchronization, the L2-distance between wave functions can be upper bounded by the inverse power of the square root of the coupling strength; as the coupling strength increases. Thus, the L2-discrepancy between wave functions arbitrarily decreases as the coupling strength increases. We present a sufficient analytical framework for this practical synchronization, which is a generalization of the earlier result in (Choi S-H and Ha S-Y 2014 J. Phys. A: Math. Theor. 47 355104)
On the formation of binary stars

Les conditions requises pour que le noyau d'un nuage moleculaire dense puisse s'effondrer pour former un systeme binaire ou multiple sont considerees. Il est suggere que la fragmentation est realisee pour former une binaire si l'effondrement est amorce par une impulsion exterieure. La nature et la dimension de l'impulsion requise sont discutees
Monitoring Expression of Balance during Therapy in Children with Postural Disorders

In the literature, we find information about the impact of changes in the shape of the spine on the efficiency of equivalent reactions, and we also find information about the methods and effects of physiotherapy in improving equivalent reactions. However, there is a lack of publications showing the process of changes taking place over time and defining their nature at individual stages of treatment. The aim of this study is to present the process of monitoring the expression of balance in patients aged 8–12 years with postural disorders, in the course of the therapeutic process. The shape of the spine and the efficiency of equilibrium reactions in standing posture and during gait were assessed in all the subjects. The subjects were put into two groups: with a shape-of-spine disorder and without one. The recommended set of therapeutic activities in home conditions lasted about 20 min and was performed by the child with a parent’s supervision. The therapeutic program was based on elements of neurophysiological methods: Vojta and PNF. The following parameters were measured: the maximum movement of the center of pressure (CoP) in the frontal plane during gait, the maximum movement of the CoP in the sagittal plane, the movement of the CoP in the frontal plane in static conditions and the movement of the CoP in the sagittal plane in static conditions. Six statistically significant differences were recorded, and all of them were related to measurement I. The Friedman test result was statistically significant for all the indexes. Post hoc analyses were performed using the Dunn–Bonferroni test. The children with shape-of-spine disorders had a lower efficiency of equivalent reactions in relation to the children without disorders. The therapy with the application of neurophysiological methods in the treatment of shape-of-spine disorders improved equilibrium reactions in these patients. Long-lasting and thorough observations of the therapeutic process in children with shape-of-spine disorders should include the monitoring of the efficiency of equilibrium reactions.
Hepatic Oxi-Inflammation and Neophobia as Potential Liver–Brain Axis Targets for Alzheimer’s Disease and Aging, with Strong Sensitivity to Sex, Isolation, and Obesity

Research on Alzheimer’s disease (AD) has classically focused on alterations that occur in the brain and their intra- and extracellular neuropathological hallmarks. However, the oxi-inflammation hypothesis of aging may also play a role in neuroimmunoendocrine dysregulation and the disease’s pathophysiology, where the liver emerges as a target organ due to its implication in regulating metabolism and supporting the immune system. In the present work, we demonstrate organ (hepatomegaly), tissue (histopathological amyloidosis), and cellular oxidative stress (decreased glutathione peroxidase and increased glutathione reductase enzymatic activities) and inflammation (increased IL-6 and TNF𝛼) as hallmarks of hepatic dysfunction in 16-month-old male and female 3xTg-AD mice at advanced stages of the disease, and as compared to age- and sex-matched non-transgenic (NTg) counterparts. Moreover, liver–brain axis alterations were found through behavioral (increased neophobia) and HPA axis correlations that were enhanced under forced isolation. In all cases, sex (male) and isolation (naturalistic and forced) were determinants of worse hepatomegaly, oxidative stress, and inflammation progression. In addition, obesity in old male NTg mice was translated into a worse steatosis grade. Further research is underway determine whether these alterations could correlate with a worse disease prognosis and to establish potential integrative system targets for AD research.
Antioxidant potential of Lycium barbarum and Delphinium denudatum to
 improve shelf life of acid-coagulated milk model system

11 ABSTRACT 12 13 Acid coagulation of milk model viz., channa is one of the common processing methods 14 of various dairy products. Channa is a traditional dairy product used as the base for many 15 sweets. Being nutrient dense, they are in peril to lysis of proteins and lipids and have lower 16 shelf-life. The present study aimed to prepare functional channa exploring antioxidants 17 p o t e n t i a l of two locally available fruit and flower Lycium barbarum and 18 Delphinium denudatum respectively to make them functional dairy products with better 19 shelf-life. The value-added channa was optimized for its processing with the incorporation 20 of 3% Lycium barbarum and 0.25% Delphinium denudatum . The value added channa was 21 optimized and standardized for its processing and subjected to an in vitro antioxidant 22 profile analysis of total phenols, total flavonoids content, DPPH, ABTS and FRAP assays 23 and product storage profile. The value-added channa prepared with 3% Lycium barbarum and 24 0.25% Delphinium denudatum was having a shelf life of more than three weeks stored at 25 refrigeration temperature . Thus, functional channa can be prepared with the fortification of 3% 26 Lycium barbarum and 0.25% Delphinium denudatum with enhanced shelf-life .
Factors Contributing to the Long-Term Sea Level Trends in the Iberian Peninsula and the Balearic and Canary Islands

We present an attempt to estimate the long-term changes in Relative Sea Level (RSL), in addition to the different factors contributing to such trends on a local and regional scale, using a statistical linear model. The time series analysis corresponded to 17 tide-gauges, grouped in three different areas: the northern and western Atlantic coasts of the Iberian Peninsula, the Canary Islands, and the southern and eastern coasts of the Iberian Peninsula and Balearic Islands. The analysis was performed for two periods: 1948–2019, using tide-gauge data; and 1993–2019, using both tide-gauge and altimetry data for comparison. The trends for the period 1948–2019 ranged between 1.09 ± 0.14 (Canary Islands) and 2.05 ± 0.21 mm/yr for the northern and western Atlantic Iberian Peninsula. Altimetry data during the period 1993–2019 yielded quite homogeneous results for all the locations and regions, ranging between 2.7 ± 0.4 and 3.0 ± 0.3 mm/yr. In contrast, the results obtained from tide-gauge data for this recent period showed a large dispersion, very likely due to local effects, or perhaps even to levelling or instrumental errors. Nevertheless, when the results were averaged for each area, the observed trends were comparable to the altimetry results, with values of 2.3 ± 0.8, 2.7 ± 0.5, and 2.8 ± 0.8 mm/yr for the three regions of study. A stepwise forward linear regression was used to relate the observed RSL variability to the atmospheric forcing and the thermosteric and halosteric components of the sea level. Surprisingly, the thermosteric and halosteric contributions were not significantly correlated to the observed RSL in many cases; consequently, the steric, the total addition of mass, the mass of salt, and the freshwater contributions to the observed sea level trends could not be reliably estimated. This result seems to have been the consequence of the scarcity of temperature and salinity data; this hypothesis was confirmed, with the exception of the tide-gauge data for L’Estartit. This location is close to a well sampled region. In this case, the atmospheric variables and the thermosteric and halosteric terms accounted for 80% of the observed RSL variance, and the contributions of these terms could be estimated. The freshwater contribution for this location was between 1.3 and 1.4 mm/yr, consistent with recent estimations of the contributions of glaciers and Greenland and Antarctica Ice Sheets. These results highlight the importance of monitoring programs and routine sampling for the determination of the different factors contributing to the sea level variability.
Characteristics of Salvia miltiorrhiza methylome and the regulatory mechanism of DNA methylation in tanshinone biosynthesis

Abstract Salvia miltiorrhiza is a model medicinal plant with significant economic and medicinal value. Its roots produce a group of diterpenoid lipophilic bioactive components, termed tanshinones. Biosynthesis and regulation of tanshinones has attracted widespread interest. However, the methylome of S. miltiorrhiza has not been analysed and the regulatory mechanism of DNA methylation in tanshinone production is largely unknown. Here we report single-base resolution DNA methylomes from roots and leaves. Comparative analysis revealed differential methylation patterns for CG, CHG, and CHH contexts and the association between DNA methylation and the expression of genes and small RNAs. Lowly methylated genes always had higher expression levels and 24-nucleotide sRNAs could be key players in the RdDM pathway in S. miltiorrhiza. DNA methylation variation analysis showed that CHH methylation contributed mostly to the difference. Go enrichment analysis showed that diterpenoid biosynthetic process was significantly enriched for genes with downstream overlapping with hypoCHHDMR in July_root when comparing with those in March_root. Tanshinone biosynthesis-related enzyme genes, such as DXS2, CMK, IDI1, HMGR2, DXR, MDS, CYP76AH1, 2OGD25, and CYP71D373, were less CHH methylated in gene promoters or downstream regions in roots collected in July than those collected in March. Consistently, gene expression was up-regulated in S. miltiorrhiza roots collected in July compared with March and the treatment of DNA methylation inhibitor 5-azacytidine significantly promoted tanshinone production. It suggests that DNA methylation plays a significant regulatory role in tanshinone biosynthesis in S. miltiorrhiza through changing the levels of CHH methylation in promoters or downstreams of key enzyme genes.
The Impact of Perceived Organizational Support on Employee Motivation in Indonesia Technology Startup Companies Post Pandemic Covid 19

Covid 19 poses significant challenges for Indonesian technology start-ups. Beginning with shifts in work modes, unstable global conditions, and geopolitics. This has caused many businesses to lay off employees, which can negatively impact employee motivation and perceptions of the organization. Perceived organizational support and motivation are crucial factors to consider in this circumstance, as the startup industry in Indonesia is rapidly growing and positively impacting the economy. This study presents an overview of the current state of perceived organizational support, autonomous motivation, and controlled motivation among employees of technology startups. It also investigates the effect of perceived organizational support on autonomous and controlled motivation among employees in Indonesian technology startups, which can be beneficial knowledge for startup practitioners. This study’s respondents involve 279 employees from Indonesian technology startups. Its analysis employs a simple linear regression method. The findings show that among employees at technology startups, perceived organizational support significantly affects autonomous motivation but has no significant effect on controlled motivation.
A Rare Case of Regorafenib-Induced ST-Elevation Myocardial Infarction

Regorafenib is an oral multi-kinase inhibitor that is used in the treatment of chemotherapy-resistant metastatic colorectal carcinoma. However, multi-kinase inhibitors have been known to cause cardiac side effects, most notably hypertension. Myocardial ischemia is a very extraordinary adverse effect of regorafenib. Our patient was a 74-year-old gentleman with stage IVa colon cancer who underwent a right colectomy with end ileostomy and was on cycle two of regorafenib during the presentation. He came in with acute onset chest pain that was intermittent, non-exertional, and radiating to the back. His left heart catheterization did not reveal any atherosclerotic lesions, and his ST-elevation myocardial infarction (STEMI) was deemed an extremely rare adverse event from regorafenib. We are herewith reporting a case of regorafenib-induced STEMI.
Sustaining Students’ Mental Health Through the Use of Tiktok Application

The relationship between social media use and an increase in mental health problems has long been established. Since the TikTok application became the most widely used app in 2019 has been an issue with the students. This study was conducted primarily to assess students’ mental health through the use of the TikTok application. Quantitative data were collected from randomly selected college students within the Province of Sultan Kudarat who are using the TikTok application for almost a year regardless of gender with a total number of thirty (30), coming from different tertiary schools in Region XII. Adapted test items in the survey questionnaire were made from Google forms and were disseminated online through messenger and Google mails, considering the Covid 19 pandemic. Descriptive analysis showed a positive impact between the level of engagement in terms of frequency of use, duration of use and the students’ use of TikTok application, the level of effects of the abovementioned application in students’ mental health; the level of students’ management of mental health in terms of academic stress, family crisis and peer pressure. Conclusion of these findings indicated that the use of TikTok application can raise awareness about the importance of using the said application with moderation and can help implement early interventions and prevention for the symptoms of any mental health issues associated with the identified common factors namely academic stress, family crisis, and peer pressure.
Espace des représentations du groupe d'un noeud classique dans un groupe de Lie

Nous donnons, sous certaines conditions, une methode generale de construction d'un arc de representations non metabeliennes d'extremite une representation abelienne donnee du groupe d'un noeud d'une sphere d'homologie rationnelle dans un groupe de Lie complexe connexe reductif. Nous determinons egalement la structure locale de la variete des representations au voisinage de la representation abelienne.
Colorectal Cancer in the Young: Research in Early Age Colorectal Cancer Trends (REACCT) Collaborative

Simple Summary Colorectal cancer is becoming more common in adults under 50. This trend has been observed worldwide, the reasons for which are unclear. Research has suggested that young patients present with more advanced diseases compared to their older counterparts yet have similar survival. How young patients respond to current treatments is unknown as they represent a small proportion of studies to date. The aim of this study is to evaluate disease-specific features and survival of patients diagnosed with colorectal cancer under 50 years of age. Increased understanding of the characteristics of early-age onset colorectal cancer will help to design age-specific preventative, diagnostic, and treatment strategies for these patients and to inform public health policies and initiatives. Abstract Background: The incidence of colorectal cancer (CRC) is increasing in the young (under 50). Defining the clinicopathological features and cancer-specific outcomes of patients with early-onset CRC is important to optimize screening and treatment strategies. This study evaluated disease-specific features and oncological outcomes of patients with early-onset CRC. Methods: Anonymized data from an international collaboration were analyzed. The inclusion criteria for this study were patients aged <50 years with stage I-III disease surgically resected with curative intent. Overall and disease-free survival were calculated using the Kaplan–Meier method. Results: A total of 3378 patients were included, with a median age of 43 (18–49) and a slight male preponderance (54.3%). One-third had a family history of colorectal cancer. Almost all (>95%) of patients were symptomatic at diagnosis. The majority (70.1%) of tumors were distal to the descending colon. Approximately 40% were node positive. Microsatellite instability was demonstrated in one in five patients, representing 10% of rectal and 27% of colon cancers. A defined inherited syndrome was diagnosed in one-third of those with microsatellite instability. Rectal cancer displayed a worse prognosis stage for stage. Five-year disease-free survival for stage I, II, and III colon cancer was 96%, 91%, and 68%, respectively. The equivalent rates for rectal cancer were 91%, 81%, and 62%. Conclusions and relevance: The majority of EOCRC would be captured with flexible sigmoidoscopy. Extending screening to young adults and public health education initiatives are potential interventions to improve survivorship.
Estimating the Elasticity of Turnover from Bunching: Preferential Tax Regimes for Solo Self-employed in Italy

Turnover is a key indicator of economic activity, but we know little about how much entrepreneurs adjust it as a response to taxation. This is because business taxation is usually based on profits, rather than turnover. This paper exploits the notch created by the eligibility cut-off of the preferential (turnover) tax regime for solo self-employed in Italy to study turnover responses to taxation. I find that solo self-employed bunch below the turnover threshold to be eligible for the preferential scheme. Effects are different in different sectors, with professionals and business intermediaries showing the largest responses. Then, I estimate the turnover tax elasticity by focusing on the (last) marginal buncher. To do so, I adapt the models of Kleven and Waseem (2013) and Harju et al. (2019) to derive a modified indifference condition that fits the institutional set-up. The baseline estimate for the turnover tax elasticity is 0.072.
Urbanization and Other Land Use Land Cover Change Assessment in the Greater Kumasi Area of Ghana

Urbanization posits the expression of urban expanse expansion due to population growth, rise in built-up areas, high population density and its corres-pondingly urban way of life. Unrestrained impetus of development and land use land cover change (LULCC) portent several issues such as unlawful urban sprawl, loss of agricultural land, forest loss and other associated complica-tions. This study analyzed the dynamics of urbanization and other LULCC in Ghana’s Greater Kumasi area via Landsat images (TM 1986, OLI 2013 and OLI 2023) using ERDAS Imagine, Idrisi and ArcGIS software. Implementing supervised classification technique, the Maximum Likelihood Classifier (MLC) procedure was employed to categories the study area into five LULC classes. Accuracy assessment undertaken on the resultant LULC maps was deemed very satisfactory. The results from 1986-2023 pointed to an upsurge in a built-up extent as of 8% to 41%, a decrease in Closed Forest from 9% to 4%, another decrease in Open Forests from 64% to 33%, a slight increase from 16% to 20% in farmlands and a stable level of water share. Further analysis indicated that the study area had undergone LULCC within the periods 1986-2013 and 2013-2023 at 60% and 37% respectively. The findings showed uncontrolled urban sprawling along major roads and forest loss as deforestation outside protected areas and degradation in protected forest. The monitoring of urbanization and other LULCC is important for local, and national governments and other bodies charged with the implementation of programs
Characterization of Flavor Profile of “Nanx Wudl” Sour Meat Fermented from Goose and Pork Using Gas Chromatography–Ion Mobility Spectrometry (GC–IMS) Combined with Electronic Nose and Tongue

Sour meat is a highly appreciated traditional fermented product, mainly from the Guizhou, Yunnan, and Hunan provinces. The flavor profiles of sour meat from goose and pork were evaluated using gas chromatography–ion mobility spectrometry (GC–IMS) combined with an electronic nose (E-nose) and tongue (E-tongue). A total of 94 volatile compounds were characterized in fermented sour meat from both pork and goose using GC–IMS. A data-mining protocol based on univariate and multivariate analyses revealed that the source of the raw meat plays a crucial role in the formation of flavor compounds during the fermentation process. In detail, sour meat from pork contained higher levels of hexyl acetate, sotolon, heptyl acetate, butyl propanoate, hexanal, and 2-acetylpyrrole than sour goose meat. In parallel, sour meat from goose showed higher levels of 4-methyl-3-penten-2-one, n-butyl lactate, 2-butanol, (E)-2-nonenal, and decalin than sour pork. In terms of the odor and taste response values obtained by the E-nose and E-tongue, a robust principal component model (RPCA) could effectively differentiate sour meat from the two sources. The present work could provide references to investigate the flavor profiles of traditional sour meat products fermented from different raw meats and offer opportunities for a rapid identification method based on flavor profiles.