Miracle-dz/UniFAR-FTUs huggingface dataset:
Role of ayurveda drugs in the management of psychological distress in adolescents: Evidences

Adolescent age group constituting 21% of India’s population is the period of rapid physical, sexual, psychological growth. Increased parental and peer pressure can put this age group into lots of stress. Poor mental health is strongly related to other health and development concerns in young people notably, lower educational achievements, substances abuse, violence and poor reproductive and sexual health. Unfortunately, modern medicine based neurological drugs have met with unsatisfactory success in treatment of various neuropsychiatric disorders due to multi-factorial nature of these diseases. The Medhya Rasayanas are a special class of Ayurvedic nutraceuticals which are specific to brain and nervous system. They are claimed to promote cognitive functions of the brain and are specifically indicated for maintenance of psychological well being. Medhya rasayana drugs play an essential role in the treatment of psychiatric and psychosomatic diseases. The mode of this therapy involves the individual to attain sedation, calmness, tranquility or a stimulation of activities of brain. Based on the experimental and clinical research, it is known that these drugs have varying degree of psychotropic action and are known to possess antidepressant, sedative and tranquilizing action. These plants are used both in herbal and conventional medicine and offer benefits that pharmaceutical drugs lack. Present review entails the evidences of medhya rasayana drugs in management of psychological distress in adolescents and reveals that these drugs have potential to alleviate the distress among adolescents.
Manoeuvring Bioactive Materials in Dentistry - A Review

Bioactivity refers to bio-inductive activity. The materials which induce such activity are bioactive materials. These materials induce a reaction from living tissue. Bioactive materials have a role in the promotion of the healing process, repair, maintaining the vitality of pulp, etc. The material should be sterile, bacteriostatic and bactericidal in nature. Bioactive materials are used in dentin remineralization, maintaining long-term restorations bonded with cement, and repairing intra-bony lesions. A biomaterial is a substance, external layer or assembly that interconnect with an organic system. Biognosisan analysis of, structure or uses of biologically generated materials, their mechanisms and processes for the formation of likely products by arti icial mechanisms that mimics natural structures. A biomaterial is a substance, external layer or assembly that interconnect with an organic system. These materials differ in their form and function and composition. Bioactive substances function works due to the inauguration of growth initiators and multiple cells. It aids in “growth, immigration, and distinction of odontoblast-like cells producing tissue matrix. Bioactive matrix form an outer layer of an apatite-like substance in association with inorganic phosphate solution. Bioactive materials like calcium hydroxide, mineral trioxide aggregate, biodentin, etc., are commonly used in routine practice. As these materials have multiple purposes, this review focuses to highlight newer materials in the category of bioactivity and their implications in dentistry particularly.
Application of Chelate and Nano-Chelate Zinc Micronutrient Onmorpho-physiological Traits and Essential Oil Compounds of Peppermint (Mentha piperita L.)

Peppermint (Mentha piperita L.) from Lamiaceae family is one of the most important medicinal plants, used in food, sanitary and cosmetic industries. The aim of this study was to examine the effects of Nano Zinc and Zinc-Chelate on morpho-physiological traits and essential oil composition of peppermint. A factorial experiment was conducted based on Randomized Complete Block Design (RCBD) with three replications in Karaj, Iran, in 2016. Treatments were zinc micronutrient in two levels (Zinc-Chelate and zinc nanoparticles) and concentration in four levels (0, 0.5, 1 and 1.5 g/l). The zinc micronutrient was applied in foliar spraying in three times of the interval of 15 days up to flowering stages. Results showed that both of Nano zinc and Zinc-Chelate micronutrient significantly increased all of morpho-physiological traits than that for control. The higher values were obtained in Zinc-Chelate (1.5 g/l) and Nano zinc (1 g/l), respectively. The effects of treatments were significant at 21 out of 34 compounds. The higher compounds with average values of 19.7%, 7.8%, 5.9%, 5.7%, 4.9% and 4.1% were obtained in Menthol, Menthone, Menthofuran, Piperitone, Menthyl acetate and Beta-caryophyllen, respectively. Nano zinc (1.5 g/l) had increased Menthol, Menthone and Menthofuran content up to 28%, 61% and 237% higher than the control, respectively. t. It was concluded that foliar spraying of Nano zinc (1 g/l) in flowering stage had increased dry matter yield and essential oil content and spraying of Nano zinc (1.5 g/l) had increased essential oil composition of peppermint.
A mediation analysis: Board of directors’ composition, R&D investment, and international firm performance

The majority of the works with financial theoretical bases try to grant an important role to the board of directors (henceforth referred as BD) as an internal mechanism of governance limiting the opportunist behaviour of the managers and to study its role and its attributes in the achievement of the performance. Seldom the studies which examined the indirect relation between the BD, which markedly differs according to the type of the national systems of governance, and the firm performance through the level of investment in research and development (henceforth referred as R&D), except for the works of Zouari and Zouari-Hadiji (2014a, 2014b). Abstract
Unusual pattern of recurrence and atypical visceral metastases in extremity soft tissue sarcoma: a case report

Soft-tissue sarcomas (STS) are a rare group of tumors, commonly arising in the extremities. For extremity STS, the main treatment strategy is limb sparing surgery followed by neoadjuvant radiotherapy. Patterns of disease relapse after multimodal treatment have been analyzed in the past decades, being the lung the first recurrence site. Non-pulmonary metastases are uncommon and are associated with worse prognosis. Local recurrences are less frequent and usually develop after a longer period of time. Local control depends on tumor grade and size, surgical margins and adjuvant radiotherapy. Here, we describe the case of an extremity STS fibrosarcoma in a 30-year-old male that in the course of the disease developed multiple marginal recurrences followed by gastric, lung and soft-tissue metastases. All local recurrences where identified by the patient himself and confirmed by magnetic resonance imaging (MRI). Limb marginal recurrences were treated with a multidisciplinary approach consisting of radical surgery and radiotherapy. Metastatic lesions were initially resected and adjuvant chemotherapy was considered after the last distant failure. STS can have an unpredictable pattern of recurrence, therefore follow-up protocols should be tailored to individual risk. Multimodal management for primary site is the key to achieve higher local control rates, and it should also be considered as an approach for secondary sites in selected patients.
IMPACT OF TREATMENT WITH DIRECT ACTING ANTIVIRAL AGENTS (DAAS) ON MIXED CRYOGLOBULINEMIA OF HCV EGYPTIAN PATIENTS

Background: Up to 74% of patients affected by HCV have HCV-related extrahepatic manifestation (EHMs) including autoimmune diseases, mixed cryoglobulinemia (MC) and non-Hodgkin lymphomas (NHL). Objective: To study the impact of treatment with direct acting antiviral agents (DAAS) on mixed cryoglobulinemia of HCV Egyptian patients. Patients and methods: This study was carried out in cooperation between the Hepato-gastroenterology and Infectious Diseases Department, Al-Azhar University, Cairo, and Shebin Elkom Fever Hospital from March 2018 to December 2019. The study included 80 patients with HCV-related EHMs including cutaneous (30 patients), musculoskeletal (30 patients) and renal manifestation (20 patients). All patients were naive to treatment with DAAs (Sofosbuvir/Daclatasvir ± Ribavirin regimen). Results: Purpuric papules of the lower extremities were the most frequent cutaneous lesion (80%), and arthralgia was the most frequent in musculoskeletal manifestations (90%). Diffuse membranoproliferative glomerulonephritis was the most frequent lesion in patients, with renal manifestations (90%). Significant increase occurred in the serum cryoglobulin levels and RF, with significant decreasein C3 and C4 serum levels in all groups. There were significant decrease in the mean cryoglobulin levels from positive to negative, with significant decline in RF concentrations, and rise in C3 and C4 serum levels approaching the normal values. There were improvements in the presenting HCV-MC clinical manifestations in variable degrees, rangingfrom 71.42% in patients with glomerulonephritis to 98.4% in patients with purpura. Eighty-seven percent of the included patients showed complete response (clinical, virologicaland immunological recovery), and 13% showed partial response (virological and immunological recovery without clinical improvement of cryoglobulinemia associated manifestations). Conclusion: DAAs, in the form of Sofosbuvir/Daclatasvir ± Ribavirin regimen, were treatment of choice for HCV infection, and considered in cases of HCV-MC as they were associated with clinical improvement in most patients.
Improved Steganography Techniques For Different Types Of Secret Data

: Steganography is an interesting aspect of data hiding art where the secret data such as (binary bits, logo, image, audio, and others) are embedded in a cover media without raising any suspicion about the existence of that data. Over the years, different steganography techniques for digital images have been presented to be applied in various applications such as security and privacy control. Some of these techniques are based on transforming the image from the spatial domain to the transform domain as a pre-processing step before embedding the secret data. This paper presents two improved steganography techniques in the transform domain based on Slantlet transform (SLT) and different data embedding methods. In the first proposed technique, a secret image can be embedded in a cover image by calculating the difference blocks of SLT coefficients and modifying the coefficients according to the root mean square error values. In the second proposed technique, a sequence of binary bits can be embedded in a cover image by modifying the carrier SLT subbands according to the secret data bits and the mean values of SLT coefficients for image’s blocks. The experimental results proved the efficiency of the proposed techniques in comparison with the previous transform-based steganography techniques.
Examining Memorable Tourism Experience On Memorable Trip Experience, Subjective Well-Being And Revisit Intention

: The present study examined the memorable tourism experience of Kim et al (2012) dimension on memorable tripe experience, subjective well-being and revisit intention. The data were collected from 362 respondents through online among the tourist in Pondicherry, India. Structural equation modeling was adopted to test the hypotheses developed for the study. The result shown the subjective well-being acted as mediating dimension between memorable trip experience and revisit intention. All the four hypotheses developed for the study were accepted. The results of the inner model demonstrate the interrelationship (including mediation effect) between the different theoretical constructs in the model. Bootstrapping (5000 re-samples), standardized root mean square (SRMR), path analysis, R-square, Stone–Geisser test or blindfolding (predictive relevance or Q 2 ) and effect size (f 2 ) analysis were performed using SmartPLS3 (Ali et al., 2018). A value less than 0.08 for SRMR is considered acceptable for PLS path models (Ali et al., 2018). Results revealed the SRMR value was 0.074, indicating an adequate model. Four path relationships were significant as presented in the above structural model assessment table. This study has few limitations. First it is highly destination specific and based on convenience sampling technique, thus the findings couldn’t be generalize to other tourism destination. Further studies can be conducted in different tourist spot to generalize the significance of this study. Next, the sample consists of only Indian citizens, in future study; foreign tourist can also be included in the sample. Finally other construct can be included to measure memorable tourism experience.
Maternal literacy and malnutrition in children: A comparative study.

Objective: Nutritional status is an important aspect of child’s health profile and affects child’s development and growth. This study aimed at exploring relationship between maternal literacy and malnutrition in children under-five years old. Methods: Two groups were made comprising of mothers, according to the nutritional status of their under-five children presenting in free clinic in Ali Raza Abad Lahore with URTI. Results: Significant difference was found in literacy level in two groups; with 38% illiteracy amongst mothers with malnourished children as compared to 14% amongst women with children not suffering from malnutrition and p value at 0.0062. More mothers of children suffering from malnutrition were found illiterate as compared to mother of well-nourished children. Conclusion: As illiteracy affected children nutrition it is recommended that illiterate women may be targeted for health education on short term basis and education be made mandatory for long term solution to this problem.
Correlation between Sonographic Findings of Maternal Thyroid Gland and Thyroid Function Tests during Pregnancy

Background: Pregnancy has great influence on maternal thyroid gland. It induces significant physiological as well as hormonal changes that alters the maternal thyroid function. Our goal was to determine this pregnancy associated changes in thyroid gland. Objective: To correlate the sonographic findings of maternal thyroid gland with thyroid function tests during pregnancy. Material and methods: 135 pregnant women were recruited in this study, data of TSH, T3 and T4 was obtained and correlated it with the sonographic findings of maternal thyroid gland in each trimester of pregnancy. Results: In the 135 sampled pregnant women, mean thyroid gland volume was 4.08±1.19 cm3. The mean levels of T3, T4 and TSH were v3.37±. 44 pmol/L, 14.96±2.49 pmol/L and 1.21±. 92 mIU/L respectively. A remarkable correlation between thyroid hormones and thyroid volume was observed. Conclusion: It is concluded that the ultra-sonographic findings is correlated with the thyroid function tests during pregnancy.
Effect of Platelet-rich Plasma in Regeneration of Thin Endometrium and Its Implications in in vitro Fertilization Cycles: A Novel Approach

The thin endometrium is an important cause of failure of cycle cancellations in in vitro fertilization (IVF). Several modalities like estrogen, low-dose aspirin, heparin, vaginal sildenafil, pentoxifylline, and granulocyte-colony stimulating factor (G-CSF) intrauterine perfusion have been tried and studied in patients with a thin endometrium. We discuss platelet-rich plasma (PRP) administration by intrauterine infusion as a novel approach in these patients. We reviewed and analyzed all important and relevant articles including case series, pilot studies, and case reports published from January 2000 to December 2020. Studies pertaining to other uses of PRP were not included. We found that intrauterine infusion of PRP can significantly increase the endometrial thickness and improve the pregnancy rates in infertile patients with thin endometrium <6 mm. How to cite this article: Pandey K, Garg R, Lal P, et al. Effect of Platelet-rich Plasma in Regeneration of Thin Endometrium and Its Implications in in vitro Fertilization Cycles: A Novel Approach. J South Asian Feder Obst Gynae 2020;12(5):313–316.
Response of Germination and Seedling Development of Cotton to Salinity under Optimal and Suboptimal Temperatures

The objective of the study was to investigate the effects of salinity stresses (50, 100, 150, 200 and 250 mM of NaCl) on germination and early seedling growth of six cotton varieties (Lydia, Carisma, Flash, BA151, BA525 and ST468) under optimum (25°C) and low temperature (18°C) conditions. Germination percentage, mean germination time, germination index, germination stress tolerance index, seedling length, vigor index, seedling fresh and dry weight of cotton varieties were investigated. Results showed that low temperature led to decreasing in germination and seedling growth, and caused retardation of mean germination time. Under suboptimal temperature, germination percentage reduced from 86.3% to 77.8% and seedling length decreased from 12.02 cm to 5.36 cm. Each increase in salinity levels higher than 50 mM resulted in decreasing in germination and seedling growth parameters of cotton varieties. No seedling growth was observed at 250 mM of NaCl at 18°C. Cotton varieties showed different tolerance levels to salinity, while they could tolerate it up to 100 mM. It was concluded that Flash and ST468 varieties exhibited better performance under salinity stresses both at optimal and suboptimal temperatures. Research Article Article History Received : 28.04. 2020 Accepted : 04.07. 2020
EFFECT OF PHYSICAL RESTRAINT GUIDELINES ON NURSES' PERFORMANCE AT MANSOURA UNIVERSITY HOSPITALS

Physical restraint is a piece of equipment or device that restricts a patient's ability to move. Restraints may keep a patient from getting out of bed or moving arms and legs excessively. The aim of this study was to establish, apply basic guidelines for nurses that dealing with restrained patients and evaluate the effect of physical restraint guidelines on nurse's performance. Methods A Quasi experimental research design was used in this study. Sample all nurses (90) that dealing with physical restraint patients were selected from the Mansoura University Hospitals. Five tools were used for data collection. Results of the present study found that, the mean age of the nurses was 28.73 ± 6.91years. In addition to all of the studied nurses had unsufficient practices score and 84.4% of them had unsufficient knowledge score as pretest, while 78.9% of the subject study had sufficient practice and 94.4% of them had sufficient knowledge after direct implementation physical restraint guidelines, on the other hand on the follow up phase the same study reveled that 63.3% of the nurses had sufficient practice while 76.7% had sufficient knowledge score regarding physical restraint application. The study concluded; there was significantly improvement in nurses’ knowledge and practice concerning to physical restraint application after implementation of physical restraint guidelines.
The communication role: the use of social networking sites in primary health care

It is well known that the growth of users on social networking sites has forced many in-stitutions to consider the relevance of this communication channel. However, nothing is known about the use of social networking sites by the ACeS – Agrupamentos de Centros de Saúde, public services integrated in the Portuguese health service (Serviço Nacional de Saúde [SNS]), whose mission is to provide primary health care, the health’s promotion and disease’s prevention as well as the connection to other services for the continuity of healthcare. At the time of its creation, in 2008, the government recognized that primary health care is the central pillar of the health system. It is argued in this study that communication should be oriented towards fulfilling the mission of the institutions. In this way, it is intended to understand how the communication pro-cess by these SNS institutions, particularly those that use social networking sites, is contributing to the fulfilment of their organisational missions. The objectives of this study were to identify the ACeS that are present on Facebook and to analyze the communication that has been developed there. The corpus of analysis consisted of the universe of all the ACeS existing in Portugal. The sources of our data were all public publications on the ACeS Facebook pages in 2018. For the systematic analysis of the data (analysis of the manifest messages), it was used the method of content analysis both with a quantitative and qualitative nature.
Study of emergency laboratory parameters in acute oraganophosphorus poisoning in a rural population- retrospective study

Introduction: Organophosphorus poisoning (OPP) is one of the common medical emergencies among rural population in India due to suicide attempts. The purpose of this study was to investigate the relationship between the initial emergency laboratory parameters (electrolytes, liver function test, random blood glucose (RBS), renal function test, Hb, RBC and WBC) and severity of organophosphate poisoning based on Bardin’s Classification and type of OP compound consumed in patients admitted to emergency department with OPP. Materials and Methods: A retrospective observational study was done in OPP patients admitted to emergency medicine department. Based on Bardin’s classification all OPP cases were classified into 3 Grades of severity of poisoning. Hematological and biochemical parameters were compared based on this severity of poisoning. Results: With random sampling of 45 patients, 19 male and 26 female patients aged between 25-35 years, admitted with OPP were included in the study. The severity of poisoning was worst in females. The pseudocholinesterase, potassium and creatinine levels were significantly low in patients of grade 3 than grade 1 and grade 2 (p <0.05, 0.05 and 0.02 respectively) poisoning. Liver enzymes (AST, ALT and ALP) were elevated in Grade 3 poisoning patients much higher than Grade 1 and Grade 2 (p value 0.004, 0.002 and 0.06 respectively). Hyperglycemia was significantly observed in Grade 3 poisoning patients at the time of admission. (p value 0.03). There was significant hypokalemia (0.02), low RBC counts (0.02) and pseudocholinesterase levels (p value 0.01) in patients who had consumed chlorpyriphos and phorate. Conclusion: Emergency laboratory parameters in acute oraganophosphorus poisoning reflect the need for basic diagnostic facility in rural area. Laboratory parameters can also serve as possible predictive markers for severe outcomes and prognosis in OP poisoning. The knowledge of type of OP compound consumed can predict the severity of OP intoxication and need for emergency intervention.