Miracle-dz/UniFAR-FTUs huggingface dataset:
Breast Cancer Survivors And Medication Adherence: The Role Of Health Beliefs, Perceptions Of Aging, And Partner Support

Aromatase inhibitors (AIs) are a daily endocrine therapy for post-menopausal breast cancer survivors and often cause difficult side effects. Women who do not adhere to AI treatment are at higher risk of cancer recurrence and mortality, yet poor adherence is a prevalent problem. This dissertation explores potentially modifiable, psychosocial predictors of AI adherence. In Chapter 1, to determine how to measure adherence in subsequent studies, we examined the psychometric properties of two self-report adherence measures. Using estrogen assays to assess convergent validity, we found that neither measure performed well; however, in exploratory analyses, a “yes/no” item about use of an AI in the past month was found to be associated with estrogen metabolite levels. In Chapter 2, we examined whether survivors’ health beliefs about AI treatment predicted their adherence behaviors. Higher perceived barriers to AI treatment, but not perceived susceptibility to cancer recurrence or perceived benefits of AI treatment, predicted non-adherence. In Chapter 3, we examined the role of arthralgia-associated aging perceptions. After controlling for the severity of arthralgia (a common side effect of AIs), we found that the risk of non-adherence was higher among women who perceived that they had aged rapidly while on the treatment. We used a mixed-methods approach in Chapter 4 to examine the role of partner support. Our qualitative findings suggest that integration of partners into follow-up care and partner support around body changes and sexual dysfunction associated with AIs may contribute to women’s ability to persist with their treatment. Our quantitative results demonstrated that satisfaction with partner support around AI treatment was determined by affection and emotional support, whereas informational and tangible support had no bearings on their satisfaction levels. Support preferences did not differ between women with lower and higher levels of pain from AI side effects; however, women with higher levels of pain tended to receive more informational support. Together, these findings can inform intervention content for women who are at risk of not adhering to AI treatment. Degree Type Dissertation Degree Name Doctor of Philosophy (PhD) Graduate Group Psychology First Advisor Dianne L. Chambless
Drivers' Assessment of Hazard Perception

Encountering dangerous situations while driving is ubiquitous. Existing research suggest that specific populations such as, novice drivers are more prone to errors in detecting and responding to driving hazards. Hazard perception training programs have been developed in attempts to improve or accelerate the acquisition of such skills. However, drivers’ attitudes and knowledge regarding vulnerable populations and hazard perception training programs remain largely unknown. Three-hundred-five participants completed an online survey assessing their beliefs about influential factors affecting hazard detection and response, perceived usefulness and preferred types of training programs, and self-assessment of driving skills. Although many existing training programs are computer-based, participants preferred on-road hazard perception training. Such findings may assist in improving existing programs, which currently fail to show nearand far-transfer effects. Similarly, novice drivers reported being most likely to engage in training programs – possibly linked to their reported high value of the usefulness of such programs and awareness of their vulnerability to commit errors. Although autonomous vehicles should mitigate these errors, researchers and government officials suggest automated vehicles will not be commercially available for 10 years. Therefore, the results of the present study provide insight into drivers’ beliefs about dangerous situations, which may prove useful in developing and improving training programs aimed at mitigating crash risk.
Implementing target range oxygen in critical care: A quality improvement pilot study

Background Iatrogenic hyperoxaemia is common on critical care units and has been associated with increased mortality. We commenced a quality improvement pilot study to analyse the views and practice of critical care staff regarding oxygen therapy and to change practice to ensure that all patients have a prescribed target oxygen saturation range. Methods A baseline measurement of oxygen target range prescribing was undertaken alongside a survey of staff attitudes. We then commenced a programme of change, widely promoting an agreed oxygen target range prescribing policy. The analyses of target range prescribing and staff survey were repeated four to five months later. Results Thirty-three staff members completed the baseline survey, compared to 29 in the follow-up survey. There was no discernible change in staff attitudes towards oxygen target range prescribing. Fifty-four patients were included in the baseline survey and 124 patients were assessed post implementation of changes. The proportion of patients with an oxygen prescription with a target range improved from 85% to 95% (χ2 = 5.17, p = 0.02) and the proportion of patients with an appropriate prescribed target saturation range increased from 85% to 91% (χ2 = 1.4, p = 0.24). The improvement in target range prescribing was maintained at 96% 12 months later. Conclusions The introduction and promotion of a structured protocol for oxygen prescribing were associated with a sustained increase in the proportion of patients with a prescribed oxygen target range on this unit.
Pemecahan Masalah Matematika (Aritmatika Sosial) Menggunakan Tradisi Marosok

Pemecahan masalah merupakan suatu proses kompleks yang menuntut seseorang untuk menyelesaikan permasalahan dengan cara menentukan masalah, mengurangi bahkan menghilangkan masalah tersebut. Salah satu cara yang digunakan manusia sebagai pemecahan masalah adalah melalui budaya. Budaya lahir dari proses berfikir manusia untuk hidup bermasyarakat. Salah satu bentuk budaya yang masih bertahan adalah Tradisi Marosok yang digunakan masyarakat Minangkabau untuk kegiatan jual beli ternak. Hal ini dilakukan masyarakat Minangkabau sebagai upaya pelestarian budaya yang kian menurun. Dengan upaya tersebut menunjukkan bahwa terlihat fenomena etnomatematika dalam tradisi Marosok. Melalui tradisi Marosok, peneliti ingin memecahkan masalah matematika yang berkaitan dengan materi aritmatika sosial. Penelitian ini menggunakan pendekatan kualitatif, dianalisis dengan deskriptif kualitatif dan teknik pengumpulan data melalui observasi, wawancara dan dokumentasi dengan teknik analisis menggunakan triangulasi data. Hasil penelitian ini menunjukkan bahwa fenomena jual beli ternak melalui tradisi marosok dapat digunakan sebagai contoh pengaplikasian pemecahan masalah matematika tentang aritmatika sosial.
ANTIHYPERTENSIVE ACTIVITY ETHANOLIC EXTRACT OF BULB ELEUTHERINE AMERICANA MERR ON FRUCTOSE-INDUCED HYPERTENSION RATS

Objective : This study aimed to evaluate ethanolic extract of bulb of Eleutherine americana Merr as antihypertensive. Methods : This study examined the effect of ethanol extract of bulb of Eleutherine americana Merr on urine volume, blood pressure, and electrocardiogram (ECG) profile. Diuretic activity was evaluated by the Lipschitz method. Furosemide (3.6 mg/kg) used as standard drug. Animal rats model of hypertension were induced by fructose 66% in the diet for 21 d. Captopril (2.5 mg/kg) used as standard antihypertension. Parameters measured were urine volume for 24 h, systolic and diastolic blood pressure, and electrocardiogram profile. Results : High fructose diet for 21 d reduced R-R, P-R interval of the electrocardiogram, increased systolic and diastolic blood pressure and heart rate compared to normal group statistically significant (p 0.05). The group received a dose of 100 mg/kg showed diuretic activity comparable to furosemide 3.6 mg/kg (p>0.05). The group received a dose of 25, 50, 100 mg/kg, showed improved on R-R, P-R interval of the electrocardiogram, and heart rate. Conclusion : It can be concluded that ethanolic extract of bulb Eleutherine americana Merr play important role in regulating blood pressure, increased urine volume and improved electrocardiogram profile.
Quality of Life for North Korean Female Refugees: The Influence of Physical Health, PTSD, and Social Support

Background of the Study.The purpose of this study was to test a mediation model that describes the pathwaysthrough which female North Korean defectors’ perceived physical health and Post-traumatic stress disorder(PTSD) symptoms may be associated with their quality of life. Specifically, we aimed to investigate whether socialsupport would mediate the association between North Korean defectors’ perceived physical health and PTSDsymptoms and their quality of life. Methods. The study sample included 172 female North Korean defectorsliving in South Korea. Participants completed a health condition checklist, the Posttraumatic Stress DisorderChecklist-Civilian Version (PLC-C), the Multidimensional Scale of Perceived Social Support (MSPSS), andthe Korean version of the Short-Form 8-Item Health Survey (SF-8). Results. The structural equation modelconfirmed the hypothesized mediation model, with the following indices: χ2 (38) = 86.184, CFI = 0.97, NFI =0.95, TLI = 0.96, RMSEA = 0.08 (90% CI: 0.06 - 0.10). Discussion. Our findings could help counselors understandunique issues that women refugees may experience as well as protective factors in their life (i.e., social support).
Educational needs of elementary school women teachers in healtheducational area

This study examines educational needs of elementary school women teachers in the health education area by means of a specially prepared questionnaire. The results show that the women teachers are very interested in health education area but at the present time they do not fully appreciate new possibilities and duties for health education that arise from new health concepts and Framework Education Programmes. The educational needs of the health education area can be on self-reflection of teachers; the can deepen the teacher qualification both cognitively and also from a personal development aspect. Those educational needs should find an edequate offer in additional education of teachers which would be composed wiht the concept of the current health issues organically included into the pedagogical theory and practice nad would bring progress in the health literacy of the teachers.
Role of diffusion weighted magnetic resonance imaging of intra and extra axial intracranial lesions

Diffusion weighted imaging (DWI) is a technique that assesses local environment at the cellular level to determine changes in the random movement of water protons. Whereas DWI is most often used to identify acute arterial ischemia, other processes that interfere with or restrict the movement of water can cause notable changes on DWI, including neoplastic lesions, encephalitis, pyogenic abscesses and occasional ABSTRACT
Novel meta-analysis pipeline of heterogeneous high-throughput gene expression datasets reveals dysregulated interactions and pathways in asthma

Introduction: Asthma is a complex and chronic inflammatory disorder with varying degrees of airway inflammation. It affects ~235 million people worldwide, and about 8% of the United States population. Unlike single-gene disorders, asthma phenotypes are guided by a highly variable combination of genotypes, making it a complex disease to study computationally. Recently, several independent high-throughput gene expression studies in bioinformatics have identified and proposed numerous molecular drivers involved in asthma initiation and progression. However, there is a poor consensus in our understanding of the molecular factors involved in the mechanism of this disease due to inherent genetic heterogeneity. Such an uncertainty in bioinformatics studies have led to a "reproducibility crisis" in the field, where similar analyses can often yield greatly varying results. In this study, we seek to harness heterogeneity in asthma by applying a meta-analysis that explores varying tissue environments. Methods: We use three publicly-available microarray gene expression datasets, belonging to different tissues in asthma patients, from NCBI's Gene Expression Omnibus (GEO). As a meta-analysis, we apply a mixed-model effect size test to determine differentially expressed (DE) genes across all three studies. Then, The datasets are pre-processed and subjected to Weighted Gene Co-expression Network Analysis (WGCNA) for identification of functional modules. Using module preservation, we determine modules in asthma that were not preserved in the healthy condition, then combine the three with a Fisher's test for a set of asthma-unique modules. These modules are explored using functional analysis (i.e. GO term analysis). Using the DE genes as well as known transcription factors, we re-construct Gene Regulatory Networks (GRNs) for each of our shortlisted modules. We then studied the topology of these GRNs using hive plots to reveal underlying dysregulations, paving the way for future analyses. Results: Our analysis reveals a novel perspective to a key interaction in asthma inflammatory regulation, the CHD4-CCL26 transcription relation. Our hive plot analysis is able to explore this gene interaction beyond the typical "over-expression, under-expression" results from typical bioinformatics studies. We reveal that CCL26, an important regulator of asthma, appears to increase in expression and topological degree in asthma, but loses connection to CHD4, which seems to be characteristic to the asthma disease. Such analysis suggests that the topology of gene networks, above simply expression values, may be key to understanding the nuanced interactions between fundamental biomarkers and drug targets in complex diseases like asthma.
Esthetic perception regarding periodontal changes: a crosssectional study

Objective: Facial appearance has become an important factor of social interaction. The perception of patients regarding the changes promoted by treatment has become a focus of study today. Thus, the proposal of the present study was to evaluate the esthetic perception of lay people regarding esthetic periodontal changes. Method: The total sample comprised 180 individuals divided into three different age groups (15-19, 35-44, and 65-74 years). Nine images with digital alterations in the gingival contour were used. One of the images served as an esthetic standard for the research (ideal image). The images were presented to the evaluators using slide show software ( Microsoft PowerPoint 2013, Microsoft, California). Was used the Wilcoxon, Kruskal-Wallis and Mann-Whitney test. The level of significance was 5% (α = 0.05). Results: Statistical differences were found between the esthetic perception of different age groups. The sample was composed only of lay people of three different age groups, and it was evident that the younger age group has a more accurate perception regarding changes in the gingival contour. Conclusion: The changes in the gingival contour perceived as less attractive were the changes between the central incisors. The younger age group had a more accurate esthetic perception in this study. KEYWORDS Periodontics; Gingival esthetics; Perception; Esthetics.
Influence of Polymer Types on the Mechanical Properties of Polymer-Modified Cement Mortars

This is an experimental study showing the effect of four types of polymers (acrylate polymer (AC), polyvinyl alcohol (PVA), styrene–butadiene rubber (SBR), and ethylene-vinyl acetate (EVA)) on the mechanical properties of polymer-modified cement mortars (PCMs). One polymer dosage was used in this study (3%), and the effect of this dosage on PCMs was compared with a control mortar mix with 0% polymer. The compressive, flexural, and pull-off bond strengths were measured and compared with previous results in works of literature. The effect of polymer addition on improving the mechanical properties of PCMs was clarified, and this effect was more obvious on the flexural strength than that on the compressive strength. The PCMs containing EVA showed the best performance, with up to 33% and 63% increases in compressive and flexural strengths after 28 days, respectively. In comparison, AC, PVA, and SBR produced smaller (16%–46% compared to control) improvements in the flexural strength after 28 days. In general, PCMs containing EVA showed the best mechanical properties.
THE ASSOCIATION BETWEEN DISTRESS AND BOTH SOCIAL SUPPORT AND SOCIAL CONSTRAINT IN RECENTLY DIAGNOSED CANCER SURVIVORS: A DAILY ASSESSMENT STUDY

OF THESIS THE ASSOCIATION BETWEEN DISTRESS AND BOTH SOCIAL SUPPORT AND SOCIAL CONSTRAINT IN RECENTLY DIAGNOSED CANCER SURVIVORS: A DAILY ASSESSMENT STUDY This study evaluated two distinct aspects of social functioning (specifically, social support and social constraint) in an attempt to increase understanding of its bidirectional relationship with distress after cancer diagnosis. Participants in this intensive longitudinal study were all recently diagnosed, first primary cervical or head/neck cancer survivors (n=47). Data collection involved a comprehensive baseline assessment and 30-day period of daily assessment (n=37) of key variables (i.e., social support, social constraint, and distress). Data were analyzed using unconditional and conditional multilevel linear models. None of the variables changed significantly over the 30-day period. On a typical day, social constraint and distress were predictive of one another (ps < .001). Social support and distress did not demonstrate a bidirectional relationship (ps > .05). In the context of cancer adjustment and survivorship, future interventions for distress should consider targeting social constraint and interventions for social constraint should consider targeting distress.
Antimicrobial activity of multifaceted lactoferrin or graphene oxide functionalized silver nanocomposites biosynthesized using mushroom waste and chitosan

Hybrid nanoparticles designed to exert multiple mechanisms of antibacterial action offer a new approach to the fight against pathogenic resistant bacteria. In this study, nanomaterials with the dual actions of antibacterial and anti-biofilm activities were developed using silver nanoparticles (AgNPs) functionalized with either lactoferrin (LTF) or graphene oxide (GO). AgNPs were synthesized using mushroom waste as a reducing agent and chitosan (CS) as a stabilizing agent, prior to their surface functionalization with either GO (AgGO) or LTF (Ag-LTF). The AgNPs exhibited a surface plasmon resonance (SPR) band at 430 nm, as determined by UV-vis spectroscopy, whereas the absorption of AgGO and Ag-LTF occurred at 402 and 441 nm, respectively. Particle size analysis of AgNPs, AgGO, and Ag-LTF revealed sizes of 121.5 ± 10.5, 354.0 ± 1.6, and 130.8 ± 1.2 nm, respectively. All AgNPs, Ag-LTF, and AgGO inhibited selected Gram-positive bacteria and Gram-negative bacteria with comparable antibacterial performance, as determined by the agar diffusion method. Despite the absence of antibacterial activity by GO and LTF, a synergistic effect of AgGO and Ag-LTF was observed as they had a greater activity against P. aeruginosa. Moreover, Ag-LTF did not affect cell viability and migration rate of cells, suggesting the non-toxicity of Ag-LTF. In conclusion, AgNPs, Ag-LTF, and AgGO possess antibacterial activity, which may offer an alternative for future antibacterial agents.
A Cyclic Game for Service-Oriented Resource Allocation in Edge Computing

Existing works adopt the Edge-Oriented Resource Allocation (EORA) scheme, in which edge nodes cache services and schedule user requests to distribute workloads over cloud and edge nodes, so as to achieve high-quality services and low latency. Unfortunately, EORA does not fully take into account the fact that service providers are sometimes independent from the edge operators with their own objectives. To deal with the conflict and cooperation between service providers and edge nodes, we devise a service-oriented resource allocation (SORA) scheme, where edge nodes and service providers adjust their resource allocations to provide requested services. We first prove that such resource allocation problem is NP-hard. We then propose a three-sided cyclic game (3CG) involving users, edge nodes, and service providers who make their individual decisions by choosing respectively high-quality services, high-value users, and cost-effective edge nodes for service deployment. Based on 3CG, we prove the existence and approximation ratio of pure-strategy Nash equilibriums (NEs). We also develop both centralized and distributed approximate algorithms for resource allocation. Finally, extensive experimental results validate the effectiveness and convergence of the proposed algorithms.
A 373-F2 0.21%-Native-BER EE SRAM Physically Unclonable Function With 2-D Power-Gated Bit Cells and ${V}_{\text{SS}}$ Bias-Based Dark-Bit Detection

This article presents a highly stable SRAM-based physically unclonable function (PUF) using enhancement–enhancement (EE)-structure bit cells for native stability improvement. The PUF bit cells are power-gated 2-D and are normally in the OFF state, which largely reduces power and is beneficial to attack tolerance. In addition, a dark-bit detection technique based on a lightweight integrated <inline-formula> <tex-math notation="LaTeX">${V}_{\text {SS}}$ </tex-math></inline-formula>-bias generator is implemented in order to screen out potentially unstable bit cells (dark bits) induced by supply voltage/temperature (VT) variations and other factors. Measured native bit error rate (BER) of prototype chips fabricated in 130-nm standard CMOS is 0.21% at 0.8 V and 23 °C, which is 14<inline-formula> <tex-math notation="LaTeX">$\times $ </tex-math></inline-formula> better compared with the conventional SRAM-based PUF. After masking the detected dark bits, no bit error (3339 bits <inline-formula> <tex-math notation="LaTeX">$\times $ </tex-math></inline-formula> 500 evaluations) appeared at the worst VT corner across 0.8 to 1.4 V and −40 °C to 120 °C. This technique also eliminated all unstable bits in the accelerated aging test. Both the data before and after dark-bit masking have passed all applicable NIST SP 800–22 randomness tests. The measured operational energy at 0.8 V is 128 fJ/bit and the standby power is 0.44 pW/bit, thanks to the 2-D power-gating scheme. The nMOS-only bit cell is highly compact, with a normalized bit cell area of 373 F <sup>2</sup>.
Revisions to Quarterly National Accounts data in Luxembourg

This study examines the revision histories of national accounts data in Luxembourg. I analyse first releases and revisions in the quarterly national accounts (QNA) published by the National Institute of Statistics (STATEC). Reliability is evaluated by measuring revision size, variability as well as the frequency in sign changes and acceleration/deceleration switches. In addition, the predictability of revisions is assessed by applying regression analysis. Overall, the results point to high uncertainty surrounding early QNA estimates, also in international comparison. I find that revisions to GDP and its components are substantial. While there is no clear evidence of a bias in year-on-year real GDP growth, this does not hold for some GDP components.