Miracle-dz/UniFAR-FTUs huggingface dataset:
Some results on λ‐designs with two block sizes

A λ‐design is a family ℬ︁ = {B1, B2, …, Bv} of subsets of X = {1, 2, …, v} such that |Bi∩Bj| = λ for all i≠jand not all Bi are of the same size. The only known example of λ‐designs (called type‐1 designs) are those obtained from symmetric designs by a certain complementation procedure. Ryser [J Algebra 10 (1968), 246–261] and Woodall [Proc London Math Soc 20 (1970), 669–687] independently conjectured that all λ‐designs are type‐1. Let g = gcd(r − 1, r* − 1), where rand r* are the two replication numbers. Ionin and Shrikhande [J Combin Comput 22 (1996), 135–142; J Combin Theory Ser A 74 (1996), 100–114] showed that λ‐designs with g = 1, 2, 3, 4 are type‐1 and that the Ryser–Woodall conjecture is true for λ‐designs on p + 1, 2p + 1, 3p + 1, 4p + 1 points, where pis a prime. Hein and Ionin [Codes and Designs—Proceedings of Conference honoring Prof. D. K. Ray‐Chaudhuri on the occasion of his 65th birthday, Ohio State University Mathematical Research Institute Publications, 10, Walter de Gruyter, Berlin, 2002, pp. 145–156] proved corresponding results for g = 5 and Fiala [Codes and Designs—Proceedings of Conference honoring Prof. D. K. Ray‐Chaudhuri on the occasion of his 65th birthday, Ohio State University Mathematical Research Institute Publications, 10, Walter de Gruyter, Berlin, 2002, pp. 109–124; Ars Combin 68 (2003), 17–32; Ars Combin, to appear] for g = 6, 7, and 8. In this article, we consider λ designs with exactly two block sizes. We show that in this case, the conjecture is true for g = 9, 11, 12, 13, 15, 16, 17, 19, 20, 21, and for g = 10, 14, 18, 22 with v≠4λ − 1. We also give two results on such λ‐designs on v = 9p + 1 and 12p + 1 points, where pis a prime. © 2010 Wiley Periodicals, Inc. J Combin Designs 19:95‐110, 2011
Chemical Composition, Antioxidant, and Antibiofilm Properties of Essential Oil from Thymus capitatus Plants Organically Cultured on the Greek Island of Lemnos

Essential oils (EOs) are mixtures of volatile plant secondary metabolites and have been exploited by humans for thousands of years for various purposes because of their many bioactivities. In this study, the EO from Thymus capitatus, a thyme species organically cultured on the Greek Island of Lemnos, was analyzed for its chemical composition (through GC-FID and GC-MS), antioxidant activity (AA), and total phenolic content (TPC), as well as its antimicrobial and antibiofilm actions against three important foodborne bacterial pathogens (Salmonella enterica ser. Typhimurium, Listeria monocytogenes, and Yersinia enterocolitica). For the latter investigations, the minimum inhibitory concentrations (MICs) and minimum biofilm inhibitory concentrations (MBICs) of the EO against the planktonic and biofilm growth of each pathogen were determined, together with the minimum biofilm eradication concentrations (MBECs). Results revealed that T. capitatus EO was rich in thymol, p-cymene, and carvacrol, presenting high AA and TPC (144.66 μmol TroloxTM equivalents and 231.32 mg gallic acid equivalents per g of EO, respectively), while its MICs and MBICs ranged from 0.03% to 0.06% v/v and 0.03% to 0.13% v/v, respectively, depending on the target pathogen. The EO was able to fully destroy preformed (mature) biofilms of all three pathogenic species upon application for 15 min, with MBECs ranging from 2.00 to 6.25% v/v. Overall, the results demonstrate that the EO of organically cultured T. capitatus presents strong antioxidant, antibacterial, and antibiofilm properties and could, therefore, be further exploited as a functional and antimicrobial natural formulation for food and health applications.
SGLT2 inhibitors among patients with heart failure with preserved ejection fraction: A meta-analysis of randomised controlled trials

Background: Sodium-glucose co-transporter 2 (SGLT2) inhibitors have been recommended in the practice guidelines for the treatment of patients with heart failure with reduced ejection fraction; however, their effects among patients with preserved ejection fraction have been debatable. Objective: We aim to evaluate the SGLT2 inhibitor effect among patients with heart failure with reduced ejection fraction, including DELIVER and EMPEROR-Preserved trials. Methods: We performed a systematic literature search using the PubMed, Embase, Scopus, and Cochrane libraries for relevant articles from inception until August 30th, 2022. Statistical analysis was performed by calculating hazard ratio (HR) using the random effect model with a 95% confidence interval (CI) and probability value (P). Statistical significance was met if 95% CI does not cross numeric “1” and P < . 05. Results: Six studies with a total of 15,989 total patients were included in the final analysis. The mean age of patients enrolled in SGLT2 inhibitors and placebo was 69.13 and 69.37 years, respectively. The median follow-up duration was 2.24 years. SGLT2 inhibitors reduced composite cardiovascular mortality or first hospitalization for heart failure (HR, 0.80 [95% CI: 0.74–0.87], P < .001, I2 = 0%), heart failure hospitalization (HR, 0.74 [95% CI: 0.67–0.82], P < .001, I2 = 0%) compared with placebo. However, all-cause mortality (HR, 0.97 [95% CI: 0.89–1.06], P = .54, I2 = 0%) and cardiovascular mortality (HR, 0.96 [95% CI: 0.82–1.13), P = . 66, I2 = 35.09%] were comparable between both groups. Conclusion: Our study finding shows that SGLT2 inhibitors significantly reduced the risk of first HF hospitalization or cardiovascular death and HF hospitalization; however, all-cause mortality was comparable between the groups.
Swine-to-Ferret Transmission of Antigenically Drifted Contemporary Swine H3N2 Influenza A Virus Is an Indicator of Zoonotic Risk to Humans

Human-to-swine transmission of influenza A (H3N2) virus occurs repeatedly and plays a critical role in swine influenza A virus (IAV) evolution and diversity. Human seasonal H3 IAVs were introduced from human-to-swine in the 1990s in the United States and classified as 1990.1 and 1990.4 lineages; the 1990.4 lineage diversified into 1990.4. A–F clades. Additional introductions occurred in the 2010s, establishing the 2010.1 and 2010.2 lineages. Human zoonotic cases with swine IAV, known as variant viruses, have occurred from the 1990.4 and 2010.1 lineages, highlighting a public health concern. If a variant virus is antigenically drifted from current human seasonal vaccine (HuVac) strains, it may be chosen as a candidate virus vaccine (CVV) for pandemic preparedness purposes. We assessed the zoonotic risk of US swine H3N2 strains by performing phylogenetic analyses of recent swine H3 strains to identify the major contemporary circulating genetic clades. Representatives were tested in hemagglutination inhibition assays with ferret post-infection antisera raised against existing CVVs or HuVac viruses. The 1990.1, 1990.4. A, and 1990.4. B.2 clade viruses displayed significant loss in cross-reactivity to CVV and HuVac antisera, and interspecies transmission potential was subsequently investigated in a pig-to-ferret transmission study. Strains from the three lineages were transmitted from pigs to ferrets via respiratory droplets, but there were differential shedding profiles. These data suggest that existing CVVs may offer limited protection against swine H3N2 infection, and that contemporary 1990.4. A viruses represent a specific concern given their widespread circulation among swine in the United States and association with multiple zoonotic cases.
The existence of full gaps and deaf bands in two-dimensional sonic crystals

Theoretical and experimental determination of sonic band structures of two-dimensional (2-D) arrays of rigid cylinders in air is reported. We present measurements for square and triangular lattices. A variational method is employed to calculate the acoustic dispersion relation. Experimentally, a transmission technique and the analysis of the phase delay between the incident and scattered waves by the structure are used to construct the acoustic bands. The comparison between theory and experiments allows to fully characterize the band gaps and it has also demonstrated the existence of deaf bands; i.e., bands which cannot be excited due to symmetry reasons. For the case of square lattice we show that the structure with a filling fraction of 0.41 has a full acoustic gap.
Reduction of Viral and Bacterial Activity by Using a Self-Powered Variable-Frequency Electrical Stimulation Device

Viruses and bacteria, which can rapidly spread through droplets and saliva, can have serious effects on people’s health. Viral activity is traditionally inhibited using chemical substances, such as alcohol or bleach, or physical methods, such as thermal energy or ultraviolet-light irradiation. However, such methods cannot be used in many applications because they have certain disadvantages, such as causing eye or skin injuries. Therefore, in the present study, the electrical stimulation method is used to stimulate a virus, namely, coronavirus 229E, and two types of bacteria, namely, Escherichia coli and Staphylococcus aureus, to efficiently reduce their infectivity of healthy cells (such as the Vero E6 cell in a viral activity-inhibition experiment). The infectivity effects of the aforementioned virus and bacteria were examined under varying values of different electrical stimulation parameters, such as the stimulation current, frequency, and total stimulation time. The experimental results indicate that the activity of coronavirus 229E is considerably inhibited through direct-current pulse stimulation with a current of 25 mA and a frequency of 2 or 20 Hz. In addition, E. coli activity was reduced by nearly 80% in 10 s through alternating-current pulse stimulation with a current of 50 mA and a frequency of 25 Hz. Moreover, a self-powered electrical stimulation device was constructed in this study. This device consists of a solar panel and battery to generate small currents with variable frequencies, which has advantages of self-powered and variable frequencies, and the device can be utilized on desks, chairs, or elevator buttons for the inhibition of viral and bacterial activities.
Diagnosis of Aspergillosis in Horses

Invasive pulmonary aspergillosis (IPA) may be a rare cause of granulomatous pneumonia in horses. The mortality of IPA is almost 100%; direct diagnostic tools in horses are needed. Bronchoalveolar lavage fluid (BALF) and serum samples were collected from 18 horses, including individuals suffering from IPA (n = 1), equine asthma (EA, n = 12), and 5 healthy controls. Serum samples were collected from another 6 healthy controls. Samples of BALF (n = 18) were analyzed for Aspergillus spp. DNA, fungal galactomannan (GM), ferricrocin (Fc), triacetylfusarinin C (TafC), and gliotoxin (Gtx). Analysis of 24 serum samples for (1,3)-β-D-glucan (BDG) and GM was performed. Median serum BDG levels were 131 pg/mL in controls and 1142 pg/mL in IPA. Similar trends were observed in BALF samples for GM (Area under the Curve (AUC) = 0.941) and DNA (AUC = 0.941). The fungal secondary metabolite Gtx was detected in IPA BALF and lung tissue samples (86 ng/mL and 2.17 ng/mg, AUC = 1).
Nuclear Starburst Activity in the Seyfert 2 Galaxy NGC 2273

We present spectrophotometric results of the Seyfert 2 galaxy NGC 2273. The presence of high-order Balmer absorption lines (H8, H9, H10) and weak equivalent widths of CaII K λ3933, CN λ4200, G-band λ4300 and MgIb λ5173 clearly indicate recent star-forming activity in the nuclear region. Using a simple stellar population synthesis model, we find that for the best fit, the contributions of a power-law featureless continuum, an intermediate-age (~ 108 yr) and an old (> 109 yr) stellar population to the total light at the reference normalization wavelength are 10.0%, 33.4% and 56.6%, respectively. The existence of recent starburst activity is also consistent with its high far-infrared luminosity (log LFIR/L☉ = 9.9), its infrared color indexes [α(25, 60) = −1.81 and α(60, 100)= −0.79, typical values for Seyfert galaxies with circumnuclear starburst], and its q-value (2.23, ratio of infrared to radio flux, very similar to that of normal spirals and starburst galaxies). Byrd et al. have suggested that NGC 2273 might have interacted with NGC 2273B in less than 109 yr ago, so the starburst activity in this galaxy could have been triggered by tidal interaction, as indicated in recent numerical simulations.
The absorption of axial acoustic waves by a perforated liner with bias flow

The effectiveness of a cylindrical perforated liner with mean bias flow in its absorption of planar acoustic waves in a duct is investigated. The liner converts acoustic energy into flow energy through the excitation of vorticity fluctuations at the rims of the liner apertures. A one-dimensional model that embodies this absorption mechanism is developed. It utilizes a homogeneous liner compliance adapted from the Rayleigh conductivity of a single aperture with mean flow. The model is evaluated by comparing with experimental results, with excellent agreement. We show that such a system can absorb a large fraction of incoming energy, and can prevent all of the energy produced by an upstream source in certain frequency ranges from reflecting back. Moreover, the bandwidth of this strong absorption can be increased by appropriate placement of the liner system in the duct. An analysis of the acoustic energy flux is performed, revealing that local differences in fluctuating stagnation enthalpy, distributed over a finite length of duct, are responsible for absorption, and that both liners in a double-liner system are absorbant. A reduction of the model equations in the limit of long wavelength compared to liner length reveals an important parameter grouping, enabling the optimal design of liner systems.
The Link Between Empty Sella Syndrome, Fibromyalgia, and Chronic Fatigue Syndrome: The Role of Increased Cerebrospinal Fluid Pressure

Abstract The etiopathogenesis of fibromyalgia (FM) and chronic fatigue syndrome (CFS) is not yet elucidated. Hypothalamo-pituitary-adrenal (HPA) axis dysfunction is reflected in the hormonal disturbances found in FM and CFS. Some study groups have introduced a novel hypothesis that moderate or intermittent intracranial hypertension may be involved in the etiopathogenesis of FM and CFS. In these conditions, hormonal disturbances may be caused by the mechanical effect of increased cerebrospinal fluid pressure, which hampers blood flow in the pituitary gland. Severe intracranial pressure may compress the pituitary gland, resulting in primary empty sella (ES), potentially leading to pituitary hormone deficiencies. The aim of this narrative review was to explore whether similar hormonal changes and symptoms exist between primary ES and FM or CFS and to link them to cerebrospinal fluid pressure dysregulation. A thorough search of the PubMed and Web of Science databases and the reference lists of the included studies revealed that several clinical characteristics were more prevalent in primary ES, FM or CFS patients than in controls, including increased cerebrospinal fluid pressure, obesity, female sex, headaches and migraine, fatigue, visual disturbances (visual acuity and eye motility abnormalities), vestibulocochlear disturbances (vertigo and neurosensorial hearing loss), and bodily pain (radicular pain and small-fiber neuropathy). Furthermore, challenge tests of the pituitary gland showed similar abnormalities in all three conditions: blunted adrenocorticotropic hormone, cortisol, growth hormone, luteinizing hormone, and thyroid stimulating hormone responses and an increased prolactin response. The findings of this narrative review provide further support for the hypothesis that moderately or intermittently increased cerebrospinal fluid pressure is involved in the pathogenesis of FM and CFS and should stimulate further research into the etiopathogenesis of these conditions.
A possible mechanism of the Asian summer monsoon-ENSO coupling

A significant coupling of the Asian summer monsoon and ENSO was examined using the NCEP/NCAR reanalysis for the period 1973-1995. Results show that a monsoon index, which is defined as meridional gradient of summertime upper-tropospheric thickness (200-500 hPa) anomalies across 20°N over the Indian subcontinent, is highly correlated with Nino-3 SST anomalies in the preceding spring. This is strongly suggestive of the presence of the indirect impact of anomalous SST forcing associated with ENSO on the Asian summer monsoon. Due to attenuated Walker circulation in response to a warm episode, convection is suppressed over the northern tropical Indian Ocean and the maritime continent from the preceding winter to spring. The suppressed tropical convection in the preceding spring generates anomalous cyclonic circulation to the west of the Tibetan Plateau as a result of the Rossby-type response to convective heating off the equator. The convection-induced anomalous cyclonic circulation accompanied by large-scale ascending atmospheric motion contributes substantially to increased rainfall and greater soil moisture, thus resulting in decreased land-surface temperature over central Asia to the northwest of the Indian subcontinent. On the other hand, warm SST anomalies are initially introduced over the tropical Indian Ocean in late spring prior to the onset of the monsoon due to the changes in the surface heat flux and/or dynamic response of the ocean to wind forcing, in intimately association with pronounced in situ low-level northeasterly wind anomalies and less cloud cover. Both these different physical processes in the land and ocean areas are crucially responsible for reduced land-ocean thermal contrast (or reduced meridional tropospheric temperature gradient), eventually bringing about the weakening of the Asian summer monsoon. The reverse situation is quite true for strong monsoon years. Once the summer monsoon becomes weak (strong) at its early stage due to these processes, the initially induced warm (cool) SST anomalies over the tropical Indian Ocean are further intensified. The mechanism proposed here is valid during the period from the late 1970s to the early 1990s when weak and strong monsoon years are categorized. During that period, the unusual Nino-3 SST anomalies tend to persist from the preceding winter until summer, hence serving as a bridge between the ENSO prevailing in the preceding winter and anomalous summer monsoon. However, regardless of when the monsoon-ENSO coupling is prominent, both the springtime outgoing longwave radiation and low-level wind anomalies dominating over the tropical Indian Ocean, associated with anomalous Walker circulation, are still crucial factors in terms of the potential predictability of the Asian summer monsoon.
Room for Feelings: A “Working Memory” Account of Affective Processing

In the past decades, affective science has overwhelmingly demonstrated the unique properties of affective information to bias our attention, memory, and decisions. At the same time, accumulating evidence suggests that neutral and affective representations rely on the same working memory substrates for the selection and computation of information and that they are therefore restricted by the same capacity limitations that these substrates impose. Here, we integrate these insights into a working memory model of affective processing (WMAP). Drawing on competitive access models of working memory, we discuss its role in the various stages of affective processing, from attentional selection to maintenance and memory storage, and resulting feelings and actions. We end our overview with some open questions and future directions.
Percolation theory on pairs of matching lattices

An important magnitude in percolation theory is the critical probability, which is defined as the supremum of those values of the occupation‐probability p, for which only finite clusters occur. In 1964 Sykes and Essam obtained the relation P(s)c(L) +P(s)c(L*) =1, where L and L* are a pair of matching lattices and P(s)c denotes the critical probability (site‐case). The proof was not complete, but based on certain assumptions about the mean number of clusters. Though Sykes and Essam suggested that the above relation holds for all mosaics (i.e., multiply‐connected planar graphs) and decorated mosaics, we have constructed a counterexample. Subsequently, for a more restricted class of graphs, an alternative derivation of the Sykes–Essam relation is given, this time based on the usual assumption that below the critical probability the mean cluster size is finite. The latter assumption is also used to prove for some nontrivial subgraphs of the simple quadratic lattice S, that their critical probability is equal .
Hierarchies of Difference Boundary Value Problems

This paper generalises the work done in Currie and Love (2010), where we studied the effect of applying two Crum-type transformations to a weighted second-order difference equation with various combinations of Dirichlet, non-Dirichlet, and affine -dependent boundary conditions at the end points, where is the eigenparameter. We now consider general -dependent boundary conditions. In particular we show, using one of the Crum-type transformations, that it is possible to go up and down a hierarchy of boundary value problems keeping the form of the second-order difference equation constant but possibly increasing or decreasing the dependence on of the boundary conditions at each step. In addition, we show that the transformed boundary value problem either gains or loses an eigenvalue, or the number of eigenvalues remains the same as we step up or down the hierarchy.
The Effect of Starting Blood Glucose Levels on Serum Electrolyte Concentrations during and after Exercise in Type 1 Diabetes

Fear of hypoglycemia is a major exercise barrier for people with type 1 diabetes (PWT1D). Consequently, although guidelines recommend starting exercise with blood glucose (BG) concentration at 7–10 mmol/L, PWT1D often start higher, potentially affecting hydration and serum electrolyte concentrations. To test this, we examined serum and urine electrolyte concentrations during aerobic exercise (cycling 45 min at 60%VO2peak) in 12 PWT1D (10F/2M, mean ± SEM: age 29 ± 2.3 years, VO2peak 37.9 ± 2.2 mL·kg−1·min−1) with starting BG levels: 8–10 (MOD), and 12–14 (HI) mmol/L. Age, sex, and fitness-matched controls without diabetes (CON) completed one exercise session with BG in the normal physiological range. Serum glucose was significantly higher during exercise and recovery in HI versus MOD (p = 0.0002 and p < 0.0001, respectively) and in MOD versus CON (p < 0.0001). During exercise and recovery, MOD and HI were not significantly different in serum insulin (p = 0.59 and p = 0.63), sodium (p = 0.058 and p = 0.08), potassium (p = 0.17 and p = 0.16), calcium (p = 0.75 and 0.19), and magnesium p = 0.24 and p = 0.09). Our findings suggest that exercise of moderate intensity and duration with higher BG levels may not pose an immediate risk to hydration or serum electrolyte concentrations for PWT1D.