Miracle-dz/UniFAR-FTUs huggingface dataset:
Toys and Toy Accessories Strike Back

Supplemental digital content is available in the text. Abstract Objective The aim of the study was to examine age-associated injury trends and severe injury proportions for plush toys, toy figurines, and doll and toy accessories. We hypothesized that the proportion of severe injuries would be highest in the younger than 3-year and 3- to 5-year age groups. Methods We analyzed injury patterns from plush toys, toy figurines, and doll and toy accessories for ages of 0 to 18 years from 2010 to 2018 using the Consumer Product Safety Commission National Electronic Injury Surveillance System. Exclusion criteria included unspecified toy categories, adult or pet involvement, or unspecified disposition. National estimates were calculated with National Electronic Injury Surveillance System sample weights. Outcome of interest was severe injury proportions per age and toy category. Severe injury was defined as life- or limb-threatening injuries or injuries requiring admission. χ2 test was used to analyze the distribution of categorical variables. Results We analyzed 1360 injuries. The majority occurred in female (n = 771, 56.7%) and ages of 3 to 5 years (n = 580, 42.7%). Annual injury frequency remained stable. One fifth of injuries were severe (n = 321, 23.6%), with a national estimate of 9304.7. The majority of both total (n = 778, 57.2%) and severe injuries (n = 182, 56.7%) resulted from toy figurines. Life-threatening injury secondary to foreign body aspiration or ingestion with a risk for asphyxiation was the most common severe injury. Severe injuries were significantly more common in the younger than 3-year group (odds ratio, 3.59; 95% confidence interval, 2.40–5.36) and 3- to 5-year age group (odds ratio, 2.97; 95% confidence interval, 2.01–4.39) than the older than 5-year age group. Conclusions Injury frequency remained stable. The greatest proportion of injuries were in ages up to 5 years, with most injuries occurring in the 3- to 5-year age category, and a significant proportion of injuries were severe.
THEORETICAL MODEL FOR SHAPED CHARGE JETS PENETRATION AND CAVITY RADIUS CALCULATION

This paper analyzes the radial response of a target due to the penetration of the shaped charge jets. The radius variation of the jet in the motion process is deduced based on the virtual origin concept. The variation of the cavity radius in the penetrating process is analyzed,and a theoretical model to describe the relation between the cavity radius and penetration,and the relation between the cavity radius and time,is developed based on the quasi-steady hydrodynamic penetration theory. A comparison between predicted results and experimental results demonstrates better agreement. This study may provide valuable references to engineering practice.
Patient Characteristics, Antimicrobial Susceptibilities, and Outcomes

Background: Morganella morganii is an unusual opportunistic pathogen causing often health care–associated infections mostly in patients with underlying comorbidities. Except for bacteremia, few studies on other types of infections caused by this organism are available. Methods: The characteristics and outcome of any type ofM.morganii infection treated at the University Hospital of Heraklion, Crete, Greece, between January 2013 and December 2018 were retrospectively studied. Results: A total of 90 patients (57.8%men;mean age ± SD, 67.8 ± 21.1 years) with M. morganii infections were identified. The patients were hospitalized in medical (52.2%), surgical (25.6%), and pediatric department (4.4%), and in the intensive care unit (10%). Only 7 (7.8%) were outpatients. The most frequent were urinary tract (34.5%), and skin and soft tissues infections (33.3%). Of all cases included, 58.9% were health careassociated, whereas in 66.7%, the infection was polymicrobial. Most patients (82.2%) had at least 1 underlying comorbidity. The clinical isolates ofM. morganii exhibited high susceptibility rates to carbapenems (100%), amikacin (98.9%), cefepime (94.4%), piperacillin/tazobactam (93.3%), and third-generation cephalosporins and aztreonam (90% each). The empirical treatment given was appropriate for 90% of the 82 patients with available data. Οverall andM.morganii infection–relatedmortality rates were 10% and 7.8%, respectively. Conclusions: AlthoughM. morganii infections are infrequently encountered in healthy individuals, they should be considered in inpatients with underlying comorbidities. The urinary tract, and the skin and soft tissues are the most frequently affected sites, whereas polymicrobial infections are very common. Appropriate antimicrobial treatment is associated with favorable prognosis.
The Role of Cognitive Conflict and Control

The purpose of this article is to provide a theoretical account of the experience of stuttering that incorporates previous explanations and recent experimental findings. According to this account, stuttering-like disfluencies emerge during early childhood from excessive detection of cognitive conflict due to subtle limitations in speech and language processes. For a subset of children who begin to stutter, the development of approach-avoidance motivational conflict likely contributes to a chronic reliance on cognitive control processes during speech. Consequently, maladaptive activation of right hemisphere inhibitory cortices to the basal ganglia via a hyperdirect pathway results in involuntary, episodic, and transient freezing of the motor system during speech initiation. This freeze response, consistent with defensive behavior in threatening situations, may lead to stuttering persistence, tension and struggle, maladaptive speech physiology, and feelings of anxiety and loss of control.
Numerical Simulation of a Generic Rocket Base Flow with Plume in a Supersonic Environment

The numerical investigation is based on three detached eddy simulations. Similar to the experiments one simulation is performed for the configuration with a closed nozzle exit. The second one includes the nozzle flow and the interaction of the plume with the base flow. A third simulation with a refined resolution of the region where the nozzle shear layer expanded has been started to address the deviation of the numerically nearly steady expansion of the plume to the experimentally observed unsteadiness of the plume. Due to the ongoing calculations the focus of the discussion is on the mean values in comparison to respective experimental results. Good agreement is achieved for the position of the recompression shock in the base flow without plume and for Pitot pressure profiles taken at the edge of the base and in the plume. The influence of the support on the boundary layer of the model is well captured. The nozzle flow and the expansion of the plume are reproduced within the accuracy of the measurements.
Recordkeeping Error or Strategic Seasonal Substitution?

This paper demonstrates workers’ compensation claims and occupational injuries recorded in the SOII show a qualitatively similar seasonal trend. These seasonal patterns are inversely related to the seasonal fluctuations in short-term disability and private insurance claims. These findings have important implications for health care providers. Objective: I compare the seasonal patterns observed in the Survey of Occupational Injuries and Illnesses (SOII) to claims data from the IBM® MarketScan® Research Databases. Methods: I construct monthly injury rates and claims rates by supplementing occupational injuries and other claims data with hours data from the Current Population Survey and estimate seasonal effects using an Unobservable Components Model. Results: While workers’ compensation data and the SOII display similar seasonal patterns, the year-end decline in the MarketScan data is 1/3 to 1/2 the magnitude observed in the SOII. Short-term disability and private health insurance claims display seasonal patterns inversely related to occupational injuries. Conclusions: Part of the year-end decline in occupational injuries observed in the SOII is likely due to recordkeeping error. There is also some evidence of strategic seasonal substitution between various health-compensation alternatives.
Genotyping of familial Mediterranean fever gene (MEFV)—Single nucleotide polymorphism—Comparison of Nanopore with conventional Sanger sequencing

Background Through continuous innovation and improvement, Nanopore sequencing has become a powerful technology. Because of its fast processing time, low cost, and ability to generate long reads, this sequencing technique would be particularly suitable for clinical diagnostics. However, its raw data accuracy is inferior in contrast to other sequencing technologies. This constraint still results in limited use of Nanopore sequencing in the field of clinical diagnostics and requires further validation and IVD certification. Methods We evaluated the performance of latest Nanopore sequencing in combination with a dedicated data-analysis pipeline for single nucleotide polymorphism (SNP) genotyping of the familial Mediterranean fever gene (MEFV) by amplicon sequencing of 47 clinical samples. Mutations in MEFV are associated with Mediterranean fever, a hereditary periodic fever syndrome. Conventional Sanger sequencing, which is commonly applied in clinical genetic diagnostics, was used as a reference method. Results Nanopore sequencing enabled the sequencing of 10 target regions within MEFV with high read depth (median read depth 7565x) in all samples and identified a total of 435 SNPs in the whole sample collective, of which 29 were unique. Comparison of both sequencing workflows showed a near perfect agreement with no false negative calls. Precision, Recall, and F1-Score of the Nanopore sequencing workflow were > 0.99, respectively. Conclusions These results demonstrated the great potential of current Nanopore sequencing for application in clinical diagnostics, at least for SNP genotyping by amplicon sequencing. Other more complex applications, especially structural variant identification, require further in-depth clinical validation.
Integrating genomic information and productivity and climate-adaptability traits into a regional white spruce breeding program

Tree improvement programs often focus on improving productivity-related traits; however, under present climate change scenarios, climate change-related (adaptive) traits should also be incorporated into such programs. Therefore, quantifying the genetic variation and correlations among productivity and adaptability traits, and the importance of genotype by environment interactions, including defense compounds involved in biotic and abiotic resistance, is essential for selecting parents for the production of resilient and sustainable forests. Here, we estimated quantitative genetic parameters for 15 growth, wood quality, drought resilience, and monoterpene traits for Picea glauca (Moench) Voss (white spruce). We sampled 1,540 trees from three open-pollinated progeny trials, genotyped with 467,224 SNP markers using genotyping-by-sequencing (GBS). We used the pedigree and SNP information to calculate, respectively, the average numerator and genomic relationship matrices, and univariate and multivariate individual-tree models to obtain estimates of (co)variance components. With few site-specific exceptions, all traits examined were under genetic control. Overall, higher heritability estimates were derived from the genomic- than their counterpart pedigree-based relationship matrix. Selection for height, generally, improved diameter and water use efficiency, but decreased wood density, microfibril angle, and drought resistance. Genome-based correlations between traits reaffirmed the pedigree-based correlations for most trait pairs. High and positive genetic correlations between sites were observed (average 0.68), except for those pairs involving the highest elevation, warmer, and moister site, specifically for growth and microfibril angle. These results illustrate the advantage of using genomic information jointly with productivity and adaptability traits, and defense compounds to enhance tree breeding selection for changing climate.
Distrust within protected area and natural resource management: A systematic review protocol

Trust is a key variable for successful natural resource management and is commonly the focus of conceptual and methodological development. Distrust, on the other hand, is frequently cited as an obstacle to management, but appears to be rarely defined, conceptually underdeveloped, and inconsistently examined. This systematic review protocol (OSF preregistration https://doi.org/10.17605/OSF.IO/GKUAW) was developed to answer two primary questions in relation to protected area and natural resource management: 1) How is distrust conceptualized, and 2) What methods are used to gather evidence of distrust? The aim is to provide a comprehensive overview of how distrust is theoretically developed and what questions are used to uncover distrust. Also, it will summarize findings on what leads to and results from distrust. Four academic and eight gray literature databases will be searched using Boolean keyword searches. Articles eligible for inclusion are those that present original research, gather and present evidence of distrust, and focus on protected areas and/or natural resource management. The review will result in a narrative synthesis that summarizes approaches to distrust within protected area and natural resource management.
Dietary choline in gonadectomized kittens improved food intake and body composition but not satiety, serum lipids, or energy expenditure

Gonadectomy is a major risk factor for feline obesity. The lipotropic effects of choline have demonstrated benefits for growth and carcass composition in livestock. The consumption of supplemental choline on body weight (BW), body composition, lipid metabolism, energy expenditure (EE), and serum satiety hormones were evaluated in 15 gonadectomized male kittens. Kittens were offered a base diet formulated for growth (3310mg choline/kg dry matter [DM]) to daily energy requirements (DER) over an 11-week acclimation. Post-gonadectomy, kittens were assigned to a base diet (CONTROL, n = 7) or choline group (base diet with additional choline at 300mg/kg BW0.75 as a top dress) (CHOLINE, n = 8). For 12-weeks post-neuter, kittens were offered three times their DER over three meals to mimic ad libitum feeding. At week -1 and 12, body composition was assessed using dual energy x-ray absorptiometry (DXA), 24-hour indirect calorimetry was performed for EE and respiratory quotients (RQ), and fasted serum samples were analyzed for lipid compounds and satiety hormones. Daily food intake (FI) and weekly BW were measured. Data was analyzed as a repeated measures of variance (ANCOVA) using the GLIMMIX procedure with time and group as fixed effects. CHOLINE had lower mean daily FI and lower rates of BW accretion (P<0.05) in contrast to CONTROL. All absolute body composition data increased over time for both groups, with lower increases in total tissue mass (P = 0.031) and fat mass (P = 0.005) in CHOLINE. Serum satiety hormones and lipid compounds did not differ (P>0.05) between groups, but both groups experienced a decrease in low-density lipoproteins and increase in high-density lipoproteins (P<0.05). Primary substrate utilization showed lipid use when fasted and use of protein or mixed macronutrients in the fed state. Fed state EE decreased post-gonadectomy (P = 0.004), however, CHOLINE did not affect total EE or RQ. These results suggest that supplemental dietary choline reduces FI, BW, and fat mass and may help to reduce the propensity of weight gain and subsequent obesity in gonadectomized feline populations.
The relation between urinary sodium and potassium excretion and risk of cardiovascular events and mortality in patients with cardiovascular disease

Background Most evidence on the relationship between sodium and potassium intake and cardiovascular disease originated from general population studies. This study aimed to evaluate the relation between estimated 24-hour sodium and potassium urinary excretion and the risk of recurrent vascular events and mortality in patients with vascular disease. Methods 7561 patients with vascular disease enrolled in the UCC-SMART cohort (1996–2015) were included. Twenty-four hour sodium and potassium urinary excretion were estimated (Kawasaki formulae) from morning urine samples. Cox proportional hazard models with restricted cubic splines were used to evaluate the relation between estimated urinary salt excretion and major adverse cardiovascular events (MACE; including myocardial infarction, stroke, cardiovascular mortality) and all-cause mortality. Results After a median follow-up of 7.4 years (interquartile range: 4.1–11.0), the relations between estimated 24-hour sodium urinary excretion and outcomes were J-shaped with nadirs of 4.59 gram/day for recurrent MACE and 4.97 gram/day for all-cause mortality. The relation between sodium-to-potassium excretion ratio and outcomes were also J-shaped with nadirs of 2.71 for recurrent MACE and 2.60 for all-cause mortality. Higher potassium urinary excretion was related to an increased risk of both recurrent MACE (HR 1.25 per gram potassium excretion per day; 95%CI 1.13–1.39) and all cause-mortality (HR 1.13 per gram potassium excretion per day; 95%CI 1.03–1.25). Conclusions In patients with established vascular disease, lower and higher sodium intake were associated with higher risk of recurrent MACE and all-cause mortality. Higher estimated 24-hour potassium urinary excretion was associated with a higher risk of recurrent MACE and all-cause mortality.
Does team-based learning affect test scores of the basic medical sciences students in a modular curriculum?

Objectives: The aim of the study was to determine the effectiveness of team-based learning (TBL) sessions as a learning tool and to assess the satisfaction level of medical students towards TBL in modular curriculum. Methods: Using the quasi-experimental study design, TBL sessions were conducted, involving students of 1st and 2nd year of Bachelor of Medicine and Bachelor of Surgery. The TBL infrastructure comprised of pre-class preparation, in-class individual readiness assurance pre-test and post-test, before and after group discussion, respectively. The responses of the students regarding TBL satisfaction were recorded through a structured questionnaire (5-point Likert-type scale) while Wilcoxon signed rank test was applied to measure the effectiveness of TBL sessions. Results: Out of 192 students, 85% agreed or strongly agreed that TBL helped them think critically, identify their knowledge gaps, boosted their confidence, and motivated them in group participation. Significantly better post-test scores were found in all modules where TBL was used as a teaching tool (Z range = -5.33 to -11.81, P < 0.00). Conclusion: TBL increases the post-test score in majority of the students, indicating improved learning process. It not only keeps students engaged throughout the learning process but incites critical thinking, problem solving skills, and confidence. Further studies are required to see long-term benefit of TBL in students’ learning.
Development and validation of new evaluation scale for measuring stroke patients’ motivation for rehabilitation in rehabilitation wards

Objective This study aimed to develop the Motivation in stroke patients for rehabilitation scale (MORE scale), following the Consensus-based standards for the selection of health measurement instruments (COSMIN). Method Study participants included rehabilitation professionals working at the convalescent rehabilitation hospital and stroke patients admitted to the hospital. The original MORE scale was developed from an item pool, which was created through discussions of nine rehabilitation professionals. After the content validity of the scale was verified using the Delphi method with 61 rehabilitation professionals and 22 stroke patients, the scale’s validity and reliability were examined for 201 stroke patients. The construct validity of the scale was investigated using exploratory factor analysis (EFA), confirmatory factor analysis (CFA), and item response theory analysis. Cronbach’s alpha confirmed its internal consistency. Regarding convergent, discriminant, and criterion validity, Spearman’s rho was calculated between the MORE scale and the Apathy Scale (AS), Self-rating Depression Scale (SDS), and Visual Analogue Scale (VAS), which rates the subjective feelings of motivation. Results Using the Delphi method, 17 items were incorporated into the MORE scale. According to EFA and CFA, a one-factor model was suggested. All MORE scale items demonstrated satisfactory item response, with item slopes ranging from 0.811 to 2.142, and item difficulty parameters ranging from -3.203 to 0.522. Cronbach’s alpha was 0.948. Regarding test-retest reliability, a moderate correlation was found between scores at the beginning and one month after hospitalization (rho = 0.612. p < 0.001). The MORE scale showed significant correlation with AS (rho = -0.536, p < 0.001), SDS (rho = -0.347, p < 0.001), and VAS (rho = 0.536, p < 0.001), confirming the convergent, discriminant, and criterion validity, respectively. Conclusions The MORE scale was verified as a valid and reliable scale for evaluating stroke patients’ motivation for rehabilitation.
A systematic review about the performance indicators related to ball possession

The purpose of this review was to investigate the influence of the performance indicators related to ball possession on the match outcome and team performance. Following the PRISMA 2020 (Preferred Reporting Items for Systematic Reviews and Meta-analyses) guidelines, this systematic review searched for literature on Web of Science, Scopus and Pub Med database, the publication date of the retrieved literature is set from January 2000 to December 2020. The keywords ‘football’ or ‘soccer’ were each paired with the following terms: ‘ball possession’, ‘ball recovery’, ‘ball regain’, ‘transition’, ‘playing style’, ‘possession zone’, ‘duration’ and ‘running performance’. The search returned 2,436 articles. After screening the records against set criteria, 75 analysis were made, and their technical and physical indicators were identified. Through analysing ball-possession related variables, the review concluded that the match outcome is not related to ball possession percentage. The ball possession percentage is not dominant to predict the match success. The status of ball possession percentage can affect the team’s performance in passing, organizational and running distance with the ball possession. There are league differences in ball possession strategies and duration. The frequency and offensive efficiency of direct ball recovery types are higher than indirect types. Ball possessions regained in the defensive third were higher than the final third. However, there remain some limitations such as the difference in the definition of concepts and sample participants, only a few studies consider the influence of situational variables and lack of in-depth analysis on ball possession strategy. Therefore, further study should adopt a more comprehensive approach, establishing a new connection between possession strategy and more technical and tactical indicators.