Miracle-dz/UniFAR-FTUs huggingface dataset:
Study of Young Indonesian's Psychological Attitude and Purchase Intention toward Slow Fashion

The current fashion system depresses resources, pollutes and destroys nature and its ecosystem. However, slow fashion encourages innovation in increasing value and relationships with customers, such as improving quality and authenticity, prioritizing local products and partners, and paying attention to fair trade principles. It is crucial to understand slow fashion, especially in developing countries with large populations. Against this background, this study examines how environmental awareness, clothing disposal behavior, shopping behavior for environmentally friendly products, and fashion interests influence psychological attitudes and purchase intentions towards slow fashion. The data collected mostly from university students majoring in home economics at three universities in Indonesia's central city. A total of 316 complete responses obtains during the investigation. SEM is used to test the predicted factors to influence psychological approaches and acquisition intentions of slow fashion products. This research shows that shopping behavior of environmentally friendly products (SBEFP), awareness of the Environment (AE), and fashion interests (FI) have a favorable result on psychological attitudes and acquisition intentions of slow fashion. However, this attitude has a partial relationship with consumption purposes concerning toward slow fashion.
Role of the Multidrug Efﬂux System MexXY in the Emergence of Moderate Resistance to Aminoglycosides among Pseudomonas aeruginosa Isolates from Patients with Cystic Fibrosis

This study investigates the role of active efﬂux system MexXY in the emergence of aminoglycoside (AG) resistance among cystic ﬁbrosis (CF) isolates of Pseudomonas aeruginosa . Three genotypically related susceptible and resistant (S/R) bacterial pairs and three other AG-resistant CF strains were compared to four non-CF strains moderately resistant to AGs. As demonstrated by immunoblot experiments, pump MexY was strongly overproduced in all of the resistant bacteria. This MexXY upregulation was associated with a 2- to 16-fold increase in the MICs of AGs in the S/R pairs and lower intracellular accumulation of dihydrostreptomycin. Alterations in mexZ , the repressor gene of operon mexXY , were found in all of the AG-resistant CF isolates and in one non-CF strain. Complementation of these bacteria with a plasmid-borne mexZ gene dramatically reduced the MICs of AGs, thus highlighting the role played by MexXY in the development of moderate resistance in CF patients. In contrast, complementation of the three non-CF strains showing wild-type mexZ genes left residual levels of resistance to
Overreaction in the Thrift IPO Aftermarket Overreaction in the Thrift IPO Aftermarket

on only a proportion of the pre-conversion market value. If we assume positive pre-conversion market value, then by con-Published Abstract We study the initial returns and long-run performance of a unique sample of thrifts that have recently converted from mutual to stock form. In addition to a full claim on all IPO proceeds, new investors in a converted thrift also receive a claim on all pre-conversion mar- ket value at no cost. Thus, the average firm in our sample has a degree of underpricing automatically built into its offer price. We find that after removing the large initial returns, cumulative excess returns for the firms in our sample are positive for 12 months after the IPO. Beginning in the second year after the IPO, the average firm in our sample undergoes a significant price correction that lasts approximately 18 months and which produces negative cumulative abnormal returns for up to 5 years post-issue. Differences in risk-ad- justed returns also indicate negative long-run returns, with poor performance concentrated in the second and third years following the IPO. The return differences are most pronounced among the small thrifts in our sample, and are broadly consistent with investor over- reaction at the time of the IPO that continues for 6–12 months before prices begin reverting back to fundamental value.
A Single Nucleotide Polymorphism of Follicle-Stimulating Hormone Receptor Gene in Turkish Women With Polycystic Ovary Syndrome: A Cross-Sectional Study A B T R A C T

S Objective: The aim of this study was to evaluate both the frequency of Asn680Ser polymorphism of follicle stimulating hormone receptor (FSHR) and whether this polymorphism is associated with polycystic ovary syndrome (PCOS) in a Turkish population. Patients and Methods: 100 patients with PCOS and 100 controls were recruited from Eastern Turkey. Venous blood samples were obtained for genetic study, hormone profile, glucose and insulin assays. Asn680Ser polymorphism of FSHR was analyzed by polymerase chain reaction (PCR) amplification and direct DNA sequencing. Two groups were compared for body mass index (BMI), modified Ferriman-Gallwey (mFG) score, fasting glucose, fasting insulin, insulin resistance, hormone and lipid status. Then, all patients were divided into subgroups for genotypes of FSHR polymorphism. These subgroups were also compared for these mentioned parameters. Results: The difference between women with PCOS and controls in allelic frequencies for Asn680Ser polymorphism of FSHR were not significant. When this single nucleotide polymorphism (SNP) at codon 680 was separately analyzed, no significant difference was found in the genotype frequency among the Asn680Asn, Asn680Ser, andSer680Ser subgroups. There were no significant differences in BMI, mFG score, levels of fasting glucose and fasting insulin, HOMA-IR, and also levels of FSH, luteinizing hormone, estradiol, prolactin, thyroid stimulating hormone, total testosterone among the PCOS patients carrying different genotypes of Asn680Ser polymorphism Conclusion: there is no association between Asn680Ser polymorphism of FSHR and PCOS in Turkish women from eastern provinces of Turkey. In addition, this SNP seems not to be associated with BMI, IR and PCOS-associated endocrine hormones.
Observational and Theoretical Investigation of Cylindrical Line Source Blast Theory Using Meteors

ii Co-Authorship Statement. iv Dedication . vi Acknowledgments. vii List of Figures . xiii List of Tables . xvii List of Appendices . xviii List of Symbols . xix Chapter 1 . 1
Validation Study of the Indonesian Internet Addiction Test among Adolescents

Background: Internet addiction is a serious problem that can negatively impact both the physical and mental health of individuals. The Internet Addiction Test (IAT) is the most common and worldwide used instrument to screen internet addiction. This study sought to investigate the psychometric properties of an Indonesian version of the IAT. Methods: A total of 643 high school students participated in the study. The IAT questionnaire was made the focus of forward translation, expert panel discussions, back translation, a face validity study, a pilot study, and a psychometric properties evaluation. Factor structure was analysed by exploratory (EFA) and confirmatory factor (CFA) analyses, whereas reliability was measured with Cronbach’s alpha coefficient. Results: The factor analysis revealed that a three-factor model of the Indonesian version of the IAT identified in the EFA displays better psychometric properties than a one-factor model of the same. The Cronbach’s alpha score is 0.855. A significant association was also observed between the level of internet addiction with gender (p = 0.027) and the duration of internet use per day (p = 0.001). Conclusion: The Indonesian version of the IAT provides good validity and reliability in a three-dimensional model. Therefore, it can be utilised as a tool for screening internet addiction in the Indonesian population.
Gene Sequences Direct Gonadotroph-Specific Expression in Transgenic Mice

Our laboratory reported previously that chimeric genes encoding either rat somatostatin (SS) or human GH (hGH), but containing the identical mouse metallothionein-l (MT) promoter/enhancer sequences and hGH 3'-flanking sequences, were selectively expressed in the gonadotrophs of transgenic mice. The experiments reported here were designed to identify the DNA sequences responsible for this unexpected cell-specific expression within the anterior pituitary. We produced new transgenic mice expressing fusion genes that tested separately the requirement of the MT or 3'-hGH sequences for gonadotroph expression. A fusion gene that retained the original MT and SS sequences, with a simian virus 40 polyadenylation signal exchanged for the 3'-hGH sequences, no longer directed strong pituitary expression, but was active in the liver. In con-trast, a cytomegalovirus promoter/enhancer-SS-hGH fusion gene was expressed at the same high level in the anterior pituitaries of transgenic mice as the originally studied MT-SS-hGH gene. Immunohistochemical analysis indicated that pituitary expression of the cytomegalovirus promoter/enhancer-SS-hGH fusion gene was also restricted to gonadotroph cells in adult mice. These studies indicate that sequences within the 3'-flanking region of the hGH gene can direct expression of chimeric genes to pituitary cells that do not normally produce growth hormone. (Molecular Endocrinology 3: 2028-2033, 1989)
AIS Electronic Library (AISeL) Knowledge Sharing Culture, Intellectual Capital and Organisational Performance

Knowledge sharing culture (KSC) and intellectual capital (IC) are two significant sources in achieving a competitive advantage and are essential for long-term success of any organization. Intellectual capital is the sum of all knowledge used to develop the process of conducting business to gain competitive advantages. However, the role of organizations’ KSC in building IC and supporting organizational performance has received limited attention, although KSC creates a context of shared values, which fosters learning and knowledge development. The main aim of this research paper is to explore how KSC and IC (human, structural and relational capital) influences organizational performance. Through a quantitative survey of 140 employees from 37 organizations in Saudi Arabia, we confirm our hypotheses that KSC is positively related to IC, and that human and relational capital is in turn positively related to organizational performance. However, we found no relationship between structural IC and organizational performance.
Possible Protective Effect or Harmful of Ketamine on Isquemia-Induced Acute Kidney Injury in a Pediatric Murine Model

The association between Ketamine and renal function begins in animal models, since the 1970s, particularly in relation to the effects on renal blood flow [1,2]. Factors on renal hemodynamics such as decreased cardiac output and blood pressure, sympathetic nerve stimulation and catecholamine release and, increased renin, angiotensin and vasopressin were involved [3]. From this century, the presence of N-Methyl-D-Aspartate Receptors (NMDA-R) outside the Central Nervous System (CNS) [4] where they had been initially identified has been proposed, whereby the existence of the NMDA-R in the kidney and its functional role becomes important [5,6] in this way, the possible effects of NMDA-R antagonists, such as ketamine.
Global Transcriptome Analysis of Staphylococcus aureus Bioﬁlms in Response to Innate Immune Cells

The potent phagocytic and microbicidal activities of neutrophils and macrophages are among the ﬁrst lines of defense against bacterial infections. Yet Staphylococcus aureus is often resistant to innate immune defense mechanisms, especially when orga-nized as a bioﬁlm. To investigate how S. aureus bioﬁlms respond to macrophages and neutrophils, gene expression patterns were proﬁled using Affymetrix microarrays. The addition of macrophages to S. aureus static bioﬁlms led to a global suppression of the bioﬁlm transcriptome with a wide variety of genes downregulated. Notably, genes involved in metabolism, cell wall syn-thesis/structure, and transcription/translation/replication were among the most highly downregulated, which was most dra-matic at 1 h compared to 24 h following macrophage addition to bioﬁlms. Unexpectedly, few genes were enhanced in bioﬁlms after macrophage challenge. Unlike coculture with macrophages, coculture of S. aureus static bioﬁlms with neutrophils did not greatly inﬂuence the bioﬁlm transcriptome. Collectively, these experiments demonstrate that S. aureus bioﬁlms differentially modify their gene expression patterns depending on the leukocyte subset encountered.
Bullying Protective Program and Its Effect on Self-efficacy and Self-esteem among Nursing Students

Bullying among nurses and nursing students is a serious issue and generates a negative culture that threatens the ethics of nursing professionals and causes burnout or turnover among nurses. Hence, we must seriously consider measures to prevent it. Moreover, self-efficacy and self-esteem is crucial for the ability and performance of nursing students in the work environment. The aim of this study was to investigate the effect of applying bullying protective program on self-efficacy and self-esteem among nursing students. A quasi-experimental research design one group pre-test, post-test and follow-up test was used. All family and community health nursing students (221) who enrolled in the fourth year-second semester of the academic year (2018-2019) at the faculty of nursing who agreed to be part in this study were included. Two tools were utilized which are General Self-Efficacy Scale (GSE) and Rosenberg's Global Self-esteem Scale, in addition to program implementation. There were statistically significant differences in both self-efficacy and self-esteem levels before and after the bullying protective program. There were a highly statistical significant improvement in the different levels of both self-esteem and self-efficacy immediately after bullying protective program and after 3 months (follow-up test) among nursing students compared to before the program where (p = 0.000). Implementation of a bullying protective program has a positive effect on improving self-efficacy and self-esteem of nursing students. Nursing curricula should integrate the concept of bullying and how to confront it in a professional manner. Also, the nursing college should set policies to eradicate the occurrence of bullying in the workplace, which creates a positive influence on the learning environment and the nursing profession as a whole.
The mechanisms and dynamics of (cid:1) v (cid:2) 3 integrin clustering in living cells

uring cell migration, the physical link between the extracellular substrate and the actin cytoskeleton mediated by receptors of the integrin family is constantly modified. We analyzed the mechanisms that regulate the clustering and incorporation of activated v 3 integrins into focal adhesions. Manganese (Mn 2 ) or mutational activation of integrins induced the formation of de novo F-actin–independent integrin clusters. These clusters recruited talin, but not other focal adhesion adapters, and overexpression of the integrin-binding head domain of talin increased clustering. Integrin clustering required immobilized ligand and was prevented D by the sequestration of phosphoinositole-4,5-bisphosphate (PI(4,5)P 2 ). Fluorescence recovery after photobleaching analysis of Mn 2 -induced integrin clusters revealed increased integrin turnover compared with mature focal contacts, whereas stabilization of the open conformation of the integrin ectodomain by mutagenesis reduced integrin turnover in focal contacts. Thus, integrin clustering requires the formation of the ternary complex consisting of activated integrins, immobilized ligands, talin, and PI(4,5)P 2 . The dynamic remodeling of this ternary complex controls cell motility.
University of Birmingham COVID-19 and Acute Sarcopenia

: The COVID-19 pandemic has had a devastating global impact, with older adults being most at risk of death from the disease. However, acute sarcopenia occurs in survivors of COVID-19; older adults and the most critically unwell patients are the most at risk. Acute sarcopenia is an under-recognised condition of acute muscle insufficiency, defined by declines in muscle function and/or quantity within six months, usually following a stressor event. This commentary reviews definition and mechanisms of acute sarcopenia in COVID-19 and suggests recommendations for research and clinical practice. Research should now focus on the longer-term consequences of acute sarcopenia in patients who have suffered from COVID-19. At the same time, clinicians need to be increasingly aware of the condition, and measurements of muscle strength, quantity, and physical performance should be embedded into clinical practice. Clinicians should consider the risks of acute sarcopenia when weighing up the risks and benefits of treatment (e.g. dexamethasone), and instigate multidisciplinary treatment including dietetics input.
IMAGING-2021.00014_proof 1..10

Background: In December 2019, pneumonia caused by coronavirus Disease-19 (COVID-19) occurred in Wuhan, Hubei Province, China. Currently, COVID-19 has spread worldwide. In accordance with the restrictions of the Hungarian Government, several epidemic hospitals and centers have been established in Hungary. The first infected patient was detected on 4th March, 2020 in our country, who was not a Hungarian citizen. The first patient died of pneumonia caused by COVID-19 was on 15 March. The Hungarian epidemic curve is flattened and more prolonged. We aimed to report our computer tomography (CT) findings in correlation with clinical status in patients with COVID-19 infection. Material and methods: All patients with laboratory-identified Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infection by real-time polymerase chain reaction (PCR) and who underwent chest CT were collected between March 26, 2020, and April 20, 2020, in our hospital. In our centre we had 107 PCR confirmed COVID-19 positive patients in this period. 52 patient (male: female 1:2, average age: 67.94) were admitted to our central epidemic hospital, according to their complains: fever, dyspnoea, hypoxaemia, altered mental status, comorbidity, sepsis or if patient isolation could not be performed. In case of every patient we took blood test, nasopharyngeal sample and a chest CT without contrast agent. In our CT report we used a score system to characterize the severity. Results: The majority of infected patients had a history of exposure in nursing homes and mostly presented with fever and cough. The present study confirmed the findings about results of other researches. The COVID-19 pneumonia affected the elderly patients, caused hypoxia, cough and sepsis. On the CT scan, typical signs were seen in the cases of PCR confirmed patients. Conclusion: The limitations of the present study include the low number of patients. Collectively, our results appear consistent with previous studies. Chest CT examination plays an important role in the diagnosis and estimation of the severity of the novel coronavirus pneumonia. Future research should examine strategically the features of the Hungarian population.
Short Communication : Genetic diversity of the IGF 2 gene as a source of genetic marker for halal authentication ANTI

Hamdani AD, Madihah, Suryohastari RB, Virgianti DP, Putrie RFW. 2018. Genetic diversity of the IGF2 gene as a source of genetic marker for halal authentication. Nusantara Bioscience 10: 203-209. The main issue of halal authenticity is the availability of reliable and rapid analytical methods to identify animal species in raw and processed food. The two most popular procedures for identifying the source of the meat are protein-based and DNA-based methods, including mass spectroscopy (MS) using a peptide marker or PCR based DNA marker, respectively. This study aims to investigate the genetic diversity of insulin-like growth factor 2 (IGF2) gene, mainly from porcine (Sus scrofa) and bovine (Bos taurus) as a source of genetic marker for halal authentication by in-silico analysis using bioinformatic tools. Multiple sequence alignment and phylogenetic tree construction of IGF2 protein sequences from representative species of mammals, birds, and fishes showed the paraphyletic relationship between the IGF2 protein of S. scrofa and B. taurus. Protein structure analysis revealed differences in helical structures near the carboxyl end of the protein, while gene analysis showed different number of exon and motifs. By in-silico analysis, we have designed a peptide marker from amino acids at position of 93-107 (S. scrofa) and 93-112 (B. taurus) from peptide preptin region that resulted in different pattern of mass spectrum between the two species. We have also identified two DNA markers that can be detected by PCR using two primers sets designed from the IGF2 transcript sequences, to examine the presence of porcine in the sample. Thus, this study provides new genetic predictive markers, derived from the IGF2 gene, to identify the source of meat for halal authentication.
A New Method of Measuring Discipline Disproportionality Applied to Title 1 Montessori and Non-Montessori Schools

Research on discipline disproportionality has been hindered by the lack of a reliable measure. In this study, we propose a novel way to measure discipline disproportionality using multilevel modeling, and we demonstrate how it resolves many of the issues inherent in more common methods—namely, relative rate ratios and risk differences. One previous study suggests there is less discipline disproportionality in Montessori schools, so we used our new method, along with more common methods, to compare discipline disproportionality in a sample of Title 1 Montessori and non-Montessori schools that was identified using propensity score matching. Results showed that overall suspension rates were significantly lower in Montessori schools but that discipline disproportionality was similar across school settings.
The Pre-NH 2 -Terminal Domain of the Herpes Simplex Virus 1 DNA Polymerase Catalytic Subunit Is Required for Efﬁcient Viral Replication

The catalytic subunit of herpes simplex virus 1 DNA polymerase (HSV-1 Pol) has been extensively studied; however, its full com-plement of functional domains has yet to be characterized. A crystal structure has revealed a previously uncharacterized pre-NH 2 -terminal domain (residues 1 to 140) within HSV-1 Pol. Due to the conservation of the pre-NH 2 -terminal domain within the herpesvirus Pol family and its location in the crystal structure, we hypothesized that this domain provides an important function during viral replication in the infected cell distinct from 5 = -3 = polymerase activity. We identiﬁed three pre-NH 2 -terminal Pol mutants that exhibited 5 = -3 = polymerase activity indistinguishable from that of wild-type Pol in vitro : deletion mutants Pol (cid:1) N43 and Pol (cid:1) N52 that lack the extreme N-terminal 42 and 51 residues, respectively, and mutant PolA 6 , in which a conserved motif at residues 44 to 49 was replaced with alanines. We constructed the corresponding pol mutant viruses and found that the pol (cid:1) N43 mutant displayed replication kinetics similar to those of wild-type virus, while pol (cid:1) N52 and pol A 6 mutant virus infection resulted in an 8-fold defect in viral yield compared to that achieved with wild type and their respective rescued derivative viruses. Additionally, both pol (cid:1) N52 and pol A 6 viruses exhibited defects in viral DNA synthesis that correlated with the observed reduction in viral yield. These results strongly indicate that the conserved motif within the pre-NH 2 -terminal domain is important for viral DNA synthesis and production of infectious virus and indicate a functional role for this domain.