Miracle-dz/UniFAR-FTUs huggingface dataset:
MIRNA-205 EXPRESSION WITH PROGRESSION OF LOW-GRADE SQUAMOUS CERVICAL INTRAEPITHELIAL LESIONS (LSIL): A PILOT STUDY

– Objective: In 2020, cervical cancer was the fourth most diagnosed cancer in women worldwide, with approximately 604,000 new cases and a total of 342,000 deaths. Human Papillomavirus (HPV) as a major risk factor for cervical cancer has been well established. MicroRNAs play a wide range of roles in physiological and pathological processes including cancer development. The aim of this study is to investigate whether miR-205 expression may be used as a novel triage approach to predict high-grade CIN as a pilot study in LBC samples from patients attending the Colposcopy Clinic at the tertiary Hospital of Tuanku Jaffar in Kuala Lumpur (Malaysia). Patients and Methods: A pilot prospective case-control study was conducted. Tissue samples were obtained from 22 patients with abnormal smears and RNA isolation was performed using miRNA PCR (Qiagen, Hilden, Germany). Results: Among the low-grade smears, 53.33% (15/22) were found to be upregulated with miR-205. A total of 5 folds of miR-205 upregulation in low-grade lesions were predictive of CIN 2 lesions. However, this was not statistically significant (p=0.097). miR-205 expression levels had a higher specificity compared to HPV testing in predicting the absence of CIN 2/3 in low-grade lesions. miR-205 expression had no association with HPV positivity, grade of smears, and histopathological findings (CIN I and CIN II). Conclusions: Upregulation of miR-205 expression had a higher specificity compared to HPV testing; however, this trend was not statistically significant. miR-205 expression had no association with HPV positivity, grade of smears and histopathological findings (CIN I and CIN II).
An approach to inferential reasoning levels on the Chi-square statistic

This paper presents an approach of progressive levels of inferential reasoning on the Chi-square statistic, going from informal to formal reasoning. The proposal is based on epistemic criteria retrieved from a historical-epistemological study of such statistic and the contributions of statistics education literature on inferential reasoning. In this regard, some theoretical and methodological notions from the onto-semiotic approach were used to identify meanings attributed to the Chi-square statistic throughout its evolution and development. The mathematical characteristics of those meanings are closely linked to the indicators of the levels proposed. The nature of the four levels on the Chi-square statistic allowed us to develop an initial approach to levels of inferential reasoning, which could be applied to other statistics such as z, student’s t and F.
Chemical Composition, Olfactory Evaluation and Antioxidant Effects of the Essential oil of Origanum Majorana L. from Albania

The chemical composition of marjoram essential oil (Origanum majorana L.) was determined by GC/FID and GC/MS. As major compounds of the oil terpinen-4-ol (21.3%), trans-sabinene hydrate (15.5%), γ-terpinene (14.0%), and α-terpinene (8.9%) were identified. The odour profile and evaluation of marjoram essential oil was established. Marjoram oil has antiradical activity with regard to DPPH, exceeding that of the phenolic component thymol. The oil exhibited scavenging effect on the hydroxyl radicals (OH•), as well, which substantially exceeded that towards the DPPH radical - the respective concentrations for 50% inhibition of the radicals (IC50) were 0. 11μg/mL for OH• and 341. 0μg/mL for DPPH. Marjoram essential oil was capable of antioxidant activity in a linoleic acid emulsion model system, where at concentration of 0.05% it inhibited conjugated dienes formation by 50.00% and the generation of linoleic acid secondary oxidized products by 79.85%.
Exploring Co-Occurrence on a Meso and Global Level Using Network Analysis and Rule Mining

Starting from a bipartite classification network of objects and classification criteria – in our case taken from Archäologische Bibliographie 1956-2007 [14] – we present a way to explore the ecology of classification co-occurrence. Enabling meso-level exploration, we construct and enrich a weighted network of classification co-occurrence with a useful lift-significance measure, based on learned association rules. Enabling global-level exploration, we use hierarchical link clustering HLC to extract sense-making communities from the co-occurrence network, taking into account that classifications can belong to multiple communities, resulting in a community overlap network. Finally, visualizing and exploring the results including evolution in time, we offer important insights regarding the structure of classical archaeology as a discipline, while making an interesting case for applying our technique to similar datasets covering other disciplines.
and Space Administration. The Observatory was made possible by the generous financial support of the W.M. Keck

We explore the redshift evolution of the metal content of damped Lyman α systems (DLAs) with new observations of four absorbers at z < 1.5; together with other recently published data, there is now a sample of ten systems at intermediate redshifts for which the abundance of Zn has been measured. The main conclusion is that the column density–weighted mean metallicity, [〈Zn/H〉] = −1.03 ± 0.23 (on a logarithmic scale), is not significantly higher at z < 1.5 than at earlier epochs, despite the fact that the comoving star formation rate density of the universe was near its maximum value at this redshift. Gas of high column density and low metallicity dominates the statistics of present samples of DLAs at all redshifts. For three of the four DLAs our observations include absorption lines of Si, Mn, Cr, Fe, and Ni, as well as Zn. We argue that the relative abundances of these elements are consistent with a moderate degree of dust depletion which, once accounted for, leaves no room for the enhancement of the α elements over iron seen in metal poor stars in the Milky Way. This is contrary to previous assertions that DLAs have been enriched solely by Type II supernovae, but can be understood if the rate of star formation in the systems studied proceeded more slowly than in the early history of our Galaxy. These results add to a growing body of data all pointing to the conclusion that known DLAs do not trace the galaxy population responsible for the bulk of star formation. Possible reasons are that sight-lines through metal rich gas are systematically underrepresented because the background QSOs are reddened, and that the most actively star forming galaxies are also the most compact, presenting too small a cross-section to have been probed yet with the limited statistics of current samples. Subject headings: cosmology:observations — galaxies:abundances — galaxies:evolution — quasars:absorption lines
Effects of Therapeutic Ultrasound on Radiation-Induced Skin Damage and Restriction of joint Mobility in Rats

This study was designed to evaluate therapeutic ultrasound (TUS) in improvement of radiation-induced skin damages and restriction of joint mobility. Eighteen adult male rats were divided into control (Con-G), 30-Gy x-ray irradiation (30 Gy-G), and 30-Gy x-ray irradiation with TUS treatment group (US-G), and then 30 Gy-G and US-G were 30 Gy irradiated to their right hind limb. US-G underwent pulsed TUS (3 MHz, 0.5 W/cm 2 , 10 min/d, 5 d/wk) to irradiated skin. The main outcome included difference in skin reaction score, ankle joint range of motion (ROM) and histological examination of skin. In our results, radiation-induced disorders were significantly severe from 14 days after x-ray irradiation, and TUS significantly improved the skin damages 28 days after x-ray irradiation and reduced the early restriction of ROM. Then, the present findings indicate the possibility of TUS as an adjuvant treatment for radiation-induced skin disorder, though further examinations for the morphological and molecular changes in the x-ray irradiated skin mediated by TUS are required.
HBANK: Monetary Policy with Heterogeneous Banks †

We study monetary, liquidity, and macroprudential policy transmission in a Heterogeneous Bank New Keynesian (HBANK) model that is solved in sequence space. Using a su ffi cient-statistic approach, we show that the combination of incomplete markets and costly bank insolvency breaks the “as-if” result, generating substantial amplification of policy shocks relative to the representative-bank benchmark. There is a trade-o ff between macroeconomic and financial stabilization: contractionary monetary policy worsens financial stability by raising the likelihood of bank insolvency in the lower tail of the bank size distribution. We enrich our baseline framework with departures from perfect deposit and credit market competition and apply it to the study of monetary, forward guidance, macroprudential, and reserve requirement policies. We validate our model empirically with novel cross-sectional and time-series facts on U.S. commercial banks.
Mathematics teachers’ self-efficacy beliefs and its relationship with teaching practices

Given that teachers’ self-efficacy belief is correlated with students’ performance and positive behavior in terms of teaching, the present study examined the teaching practices of mathematics teachers and their self-efficacy beliefs with regard to some variables (gender, educational background, teaching phase, and school type). This study is underpinned by a positivist paradigm and a quantitative research approach. The researchers employed a survey research design. The population for this study is made up of all mathematics teachers in schools located in the Eastern Cape Province, South Africa from which a total of 266 mathematics teachers teaching in senior phase, further education and training phase, and intermediate phase were randomly sampled. In order to collect data, teachers teaching practice self-efficacy scale, which consisted of 23 items and four dimensions was employed. One-way analysis of variance, independent samples t-test, and arithmetic mean were conducted in analyzing the collected data. Despite having a high degree of confidence in their instructional strategies, teachers’ low self-efficacy beliefs were found to be influenced by the kind of schools, where they were teaching and their level of education. Based on these findings, it was recommended that relevant stakeholders in the education sector should make schools conducive to learning through the provision of required instructional materials that supports the teaching and learning of mathematics.
Octocoral Symbiodiniaceae, but not bacterial communities, are resistant to compositional changes from heat stress on a subtropical reef Short title: heat stress and the octocoral holobiome

Microbes are essential to the holobiome of all organisms, so when organisms are impacted by environmental stressors the changes to microbial communities can inform on the health state of the host and even cause host disease. In early 2019 marine heatwaves occurred across eastern Australia, resulting in differential bleaching across Lord Howe Island reefs. Here we examined the Symbiodiniaceae and bacteria associated with bleaching susceptible Cladiella sp.1, and Symbiodiniaceae associated with two bleaching resistant octocoral species – Cladiella sp.2 and Xenia cf crassa – during and after marine heatwaves and between two reefs, Sylphs Hole (heavily impacted) and Coral Gardens (mildly impacted). While we found that Cladiella sp.1 Symbiodiniaceae community structure was not altered by bleaching, beta diversity dispersion of Symbiodiniaceae in unbleached colonies was higher at Sylphs Hole than Coral Gardens, suggesting dysbiosis. Unbleached colonies of all species had different Symbiodiniaceae communities between reef sites, and communities were stable through time. Bacterial communities differed between bleached and unbleached Cladiella sp.1, and bleached colonies’ microbial communities changed after bleaching alert levels returned to “no stress”, showing a delayed microbial response to bleaching. Finally, unbleached colonies from Sylphs Hole had higher bacterial alpha diversity compared to colonies at Coral Gardens, which together with possible Symbiodiniaceae dysbiosis suggests that the unbleached colonies at Sylphs Hole were impacted by heatwaves without clear physical changes in the field. So, corals and their microbial communities may be affected at heavily stressed sites regardless of bleaching status.
Facile preparation of low-cost HKUST-1 with lattice vacancies and high-efficiency adsorption for uranium

In this work, we prepared HKUST-1 and HKUST-1 with lattice vacancies (HLV) using benzoic acid (BA) as a low-cost modulator to replace part of the traditional trimesic acid ligand (H3BTC). The structure and morphology of the products were characterized by FTIR, XRD, SEM and XPS. The adsorption performance of the products for uranium from aqueous solutions was investigated. The results showed that the sorption of U(vi) on HKUST-1 and HLV agreed with the Langmuir isotherm model (RHKUST-12 = 0.9867 and RHLV2 = 0.9828) and the maximum adsorption capacity was 430.98 mg g−1 and 424.88 mg g−1, respectively. According to kinetics studies, the adsorption fitted better with a pseudo-second-order model (RHKUST-12 = 1.0000 and RHLV2 = 0.9978). The as-prepared adsorbents were used for the removal of uranium from real water samples as well. The results showed that HLV with lower cost is a promising adsorbent for uranium from aqueous solutions.
What factors influence the rediscovery of lost tetrapod species?

We created a database of lost and rediscovered tetrapod species, identified patterns in their distribution and factors influencing rediscovery. Tetrapod species are being lost at a faster rate than they are being rediscovered, due to slowing rates of rediscovery for amphibians, birds and mammals, and rapid rates of loss for reptiles. Finding lost species and preventing future losses should therefore be a conservation priority. By comparing the taxonomic and spatial distribution of lost and rediscovered tetrapod species, we have identified regions and taxa with many lost species in comparison to those that have been rediscovered-our results may help to prioritise search effort to find them. By identifying factors that influence rediscovery, we have improved our ability to broadly distinguish the types of species that are likely to be found from those that are not (because they are likely to be extinct). Some lost species, particularly those that are small and perceived to be uncharismatic, may have been neglected in terms of conservation effort, and other lost species may be hard to find due to their intrinsic characteristics and the characteristics of the environments they occupy (e.g. nocturnal species, fossorial species and species occupying habitats that are more difficult to survey such as wetlands). These lost species may genuinely await rediscovery. However, other lost species that possess characteristics associated with rediscovery (e.g. large species) and that are also associated with factors that negatively influence rediscovery (e.g. those occupying small islands) are more likely to be extinct. Our results may foster pragmatic search protocols that prioritise lost species likely to still exist.
How do pre-service teachers view Galois theory? A questionnaire study

Abstract algebra is an important part of mathematics teacher education as it provides the rigorous mathematical foundations for many mathematics topics covered in school classrooms. Throughout their academic career, many secondary mathematics teachers even enroll in more advanced algebra courses, which often culminate in Galois theory. However, very little is known about educational aspects of Galois theory and respective mathematics education research is scarce. We contribute to closing this gap by reporting on the results of an exploratory questionnaire study with a sample of n=39 pre-service mathematics teachers, inquiring about the raison d’être of incorporating Galois theory into teacher education: Is Galois theory viewed as useful for their later profession and which connections are drawn to the secondary mathematics classroom? On the one hand, the results of our study indicate that a vast majority of pre-service teachers do not perceive studying Galois theory as meaningful and struggle to exemplify connections between Galois theory and secondary school mathematics. On the other hand, a small share of the participants experienced Galois theory as an important part of mathematics that elegantly connects a variety of algebraic and geometric notions.
Prizewinning Dissertation 2022

Eastern European and former Soviet Union countries transitioned from command to market economy after the Cold War. The market was blamed for poor health consequences and increasing tobacco consumption throughout this shift. This study enters the state vs market debate by focusing on the state's function. A regression with fixed effects is run to study the correlation between foreign direct investments, as a proxy for the market, and state quality, as a proxy for the state, on tobacco consumption, as a component of development. Findings suggest that the state, not the market, may have influenced tobacco use and, consequently, development
Shelf­life and post­harvest quality of tomato ( Lycopersicon esculen‐ tum Mill.) varieties to diﬀerent packaging materials at Mersa, North Wollo, Ethiopia

: Tomato (Lycopersicon esculentum Mill.) has a short shelf life at ambi­ ent conditions and is a highly perishable crop. Extreme post­harvest losses occur as a result of the wrong packaging materials. However, by employing the right packing materials, tomato varietals can have longer shelf lives. Globally rising fresh tomato demand has forced the development of essential mecha­ nisms, including packaging materials, to improve shelf life. The current study was initiated to evaluate the quality and shelf­life of tomato varieties in response to packaging materials at Mersa, North Wollo, Ethiopia, during 2021 cropping season. Three replications of a completely randomized design were used to test three tomato varieties (Roma VF, Oval red and Woyno) and seven packing materials [closed carton (CC), open carton (OC), closed wooden box (CWB), open wooden box (OWB), perforated polyethylene bag (PPB), non­per­ forated polyethylene bag (NPPB) and control (C)] at room temperature (20­ 22°C). According to the ﬁndings, there is a signiﬁcant (P<0.05) interaction eﬀect between packaging materials and varieties on a number of parameters, includ­ ing physiological weight loss, decay percentage, disease incidence, total soluble solids (TSS), tomato fruit PH, juice color score, overall acceptability, marketabil­ ity percentage, and shelf life. Non­perforated polyethylene plastic experienced the highest physiological weight losses of 79.88% and 79.63% after
Human occupation of the northern Arabian interior during early Marine Isotope Stage 3

The early part of Marine Isotope Stage (MIS) 3 (ca. 60–50 ka) is a crucial period for studying human demography and behaviour in south‐west Asia, and how these relate to climatic changes. However, the archaeological and palaeoenvironmental records for MIS 3 in critical areas such as the Arabian Peninsula remain poorly developed. Here, we present findings from the Al Marrat basin in the Nefud desert, which provides the first clear evidence for both increased humidity and human occupation of the interior of northern Arabia during early MIS 3. A Middle Palaeolithic assemblage, dated by optically stimulated luminescence to ca. 55 ka, was found stratified within a sequence of relict palustrine deposits indicative of shallow water body formation in the Al Marrat basin. Hominin presence in northern Arabia at this time coincides with the intensification and northward displacement of monsoon rainfall systems during a period of maximum insolation. These findings add to a growing corpus of palaeoenvironmental evidence, which indicates that the Arabian interior was neither arid nor unpopulated during early MIS 3, and that hydrodynamic responses to enhanced moisture availability facilitated demographic expansions into the Arabian interior.
Seasonal Variation of Water Mass Distributions in the Eastern Yellow Sea and the Yellow Sea Warm Current

【A seasonal circulation pattern in the eastern Yellow Sea (EYS) is suggested from the water mass analysis and geostrophic calculation using the hydrographic data collected by National Fisheries Research and Development Institute during the years of 1970 to 1990. This research focuses on the presence of inflow of warm (and saline) waters into EYS in summer. EYS is divided into two regions in this paper: the west coast of Korea (WCK) and the central Yellow Sea (CYS). In CYS, waters are linked with warm waters near Cheju Island in winter, but with cold waters from the north in summer (in the lower layer). It is not simple to say about WCK because of the influences of freshwater input and tidal mixing. Nevertheless, water mass analysis reveals that along WCK, waters have the major mixing ratios (40-60%) of warm waters in summer, while the dominant mixing ratios (50-90%) of cold waters in winter. Such a seasonal change of water mass distribution can be explained only by seasonal circulation. In winter, warm waters flow northward into CYS and cold waters flow southward along WCK. In summer, warm waters flow northward along WCK and cold waters flow southward into CYS. This circulation pattern is supported by both statistical analysis and dynamic depth topography. Accordingly, Yellow Sea Warm Current may be defined as the inflow of warm waters to CYS in winter and to WCK in summer. 】
Alcohol consumption and protective behavioural strategy use among Australian young adults

Alcohol is an important feature of most modern Western societies and since European settlement alcohol has played an important role in the social, economic, and political culture of Australia. Alcohol consumption is widely accepted and has become an integral part of Western culture; in particular playing an important role in the lives of young adults as they negotiate their entry into adulthood (Roche et al., 2007). However, it is only in fairly recent times that a culture of bingedrinking has become truly noticeable through worldwide media attention (Alcohol Education and Rehabilitation Foundation [AERF], 2007; Australian Medical Association [AMA], 2008; Department of Health and Ageing, 2008; Martinic & Measham, 2008; Roche et al., 2007; West, 2008).