Miracle-dz/UniFAR-FTUs huggingface dataset:
Modal Decomposition Techniques: Application in Coherent Structures for a Saccular Aneurysm Model

Aneurysms are localized expansions of blood vessels which can be fatal upon rupture. Studies have shown that aneurysm flows exhibit complex flow phenomena which consist of single or multiple vortical structures that move within the flow cycle. Understanding the complex flow behaviors of aneurysms remain challenging. Thus, the goal of this study is to quantify the flow behavior and extract physical insights into aneurysm flows using advance data decomposition methods, Proper Orthogonal Decomposition (POD) and Dynamic Mode Decomposition (DMD). The velocity field data were obtained by performing 2D Particle Image Velocimetry (2D PIV) on the mid-plane of an idealized, rigid, saccular aneurysm model. The input flow conditions were set to Rep=50 and 150 for a fixed α=2 using a precisely controlled piston pump system. POD was used to quantify the spatial features of the flows, while DMD was used to obtain insight on the dynamics. The results obtained from POD and DMD showed the capability of both methods to quantify the flow field, with the modes obtained providing different insights into the flow evolution in the aneurysm. The curve-fitting step of the POD time-varying coefficients, and the appropriate selection of DMD modes based on their energy contribution, allowed the mathematical flow models from POD and DMD to reconstruct flow fields at any given time step. This can be used for validation of numerical or computational data.
Pengaruh Jumlah Desa Wisata dan Jumlah Kunjungan Wisatawan Desa Wisata Terhadap Pendapatan Asli Daerah di Provinsi D.I. Yogyakarta

This study aims to see how the influence of the number of tourist villages and the number of tourist village visits on local revenue in the Province of D.I. Yogyakarta. The data used in this study is secondary data for 2016-2020 obtained from BPS D.I. Yogyakarta. The analysis used is multiple linear analysis with the help of the eviews 10 application. Based on the results of the analysis of the number of tourist villages and the number of tourist visits to tourist villages simultaneously, there is no significant effect on local revenue in the Province of D.I. Yogyakarta. Partially, the variable number of tourist villages has a significant effect on local revenue in the Province of D.I. Yogyakarta, while the variable number of tourist visits to tourist villages has no significant effect on local revenue in the Province of D.I. Yogyakarta.
LGBT Tourism in South Africa: the influence of customer value on behavioural intention

ABSTRACT The potential economic contributions of the LGBT tourism market have received the attention of scholars, destination marketing practitioners and tourism businesses, highlighting the LGBT society as a lucrative market, while also signifying the distinctive needs of the LGBT community. This study investigates the impact of customer value on behavioural intentions in the LGBT tourism sector. Data was collected from 406 LGBT tourists using a self-administered electronic questionnaire. Data analysis was performed using the partial least squares structural equation modelling (PLS-SEM) technique. Results indicate that two out of five identified dimensions of customer value (functional value and emotional value) significantly impact customer value. Furthermore, customer value has a positive and significant impact on word of mouth. The results provide an understanding of important dimensions of creating customer value for LGBT tourism destinations. Managerial implications for LGBT tourism destinations are drawn from the research findings, and suggestions for future research are presented.
The Structure and Function of Next-Generation Gingival Graft Substitutes—A Perspective on Multilayer Electrospun Constructs with Consideration of Vascularization

There is a shortage of suitable tissue-engineered solutions for gingival recession, a soft tissue defect of the oral cavity. Autologous tissue grafts lead to an increase in morbidity due to complications at the donor site. Although material substitutes are available on the market, their development is early, and work to produce more functional material substitutes is underway. The latter materials along with newly conceived tissue-engineered substitutes must maintain volumetric form over time and have advantageous mechanical and biological characteristics facilitating the regeneration of functional gingival tissue. This review conveys a comprehensive and timely perspective to provide insight towards future work in the field, by linking the structure (specifically multilayered systems) and function of electrospun material-based approaches for gingival tissue engineering and regeneration. Electrospun material composites are reviewed alongside existing commercial material substitutes’, looking at current advantages and disadvantages. The importance of implementing physiologically relevant degradation profiles and mechanical properties into the design of material substitutes is presented and discussed. Further, given that the broader tissue engineering field has moved towards the use of pre-seeded scaffolds, a review of promising cell options, for generating tissue-engineered autologous gingival grafts from electrospun scaffolds is presented and their potential utility and limitations are discussed.
Kinetic Gait Parameters in Unilateral Lower Limb Amputations and Normal Gait in Able-Bodied: Reference Values for Clinical Application

Unilateral lower limb amputations usually present with asymmetric interlimb gait patterns, in the long term leading to secondary physical conditions and carrying the risk of low physical activity and impairment of general health. To assess prosthetic fittings and rehabilitation measures, reference values for asymmetries as well as the most significant gait parameters are required. Kinetic gait data of 865 patients with unilateral lower limb amputations (hip and knee disarticulations, transfemoral, transtibial and foot amputations) and 216 able-bodied participants were quantitatively assessed by instrumented gait analyses. Characteristic spatiotemporal (stance time, walking speed, step length and width) and ground reaction force parameters (weight-acceptance and push-off peak) were contrasted to normal gait. All spatiotemporal and ground reaction force parameters differed significantly from normal gait with the largest differences in transfemoral amputations. These also differed between amputation levels and showed age-dependencies. The stance time and push-off peak difference were identified as the most discriminative parameters with the highest diagnostic specificity and sensitivity. The present results mark the first step to establishing universal reference values for gait parameters by means of which the quality and suitability of a prosthetic fitting and the rehabilitation progress can be assessed, and are generalizable for all adults with unilateral lower limb amputations in terms of level walking.
PLL Based Sub-/Super-Synchronous Resonance Damping Controller for D-PMSG Wind Farm Integrated Power Systems

Existing sub-/super-synchronous (SSO) suppression methods for the direct-drive permanent magnet synchronous generators (D-PMSG) integrated power systems are mainly achieved by external devices or sub-synchronous resonance damping controller (SSRDC) at the converters, facing challenges of considerable control costs, complex parameters tuning, or inadaptability to various operating conditions. To address these problems, this paper proposes an adaptive SSRDC based on the phase-locked loop (PLL) for D-PMSG integrated power systems. Firstly, the PLL parameter is found critical to SSO suppression by a comprehensive sensitivity analysis on the dominant poles of the impedance closed-loop transfer function. Motivated by this finding, this paper then designs a PLL-based SSRDC, which features a simple structure, easy parameter tuning, and flexible adaptability to various operating modes. The simplicity in structure is guaranteed by the avoidance of phase compensation. Benefiting from the simple structure, only one key parameter needs to be tuned. Moreover, two principles of parameter tuning are proposed to enhance the efficiency, robustness, and adaptability of the proposed SSRDC. The controller-hardware-in-the-loop (CHIL) tests verify the validity of the proposed SSRDC under various operating conditions. Finally, some concerns about this method such as frequency estimation, computational efficiency and potential impacts on PLL are thoroughly analyzed and clarified.
Hormonal Fluctuations and Periodontal Status in Postmenopausal Women

Introduction While the short-term effects of hormonal events on gingival inflammation have been well described, their long-term effects on the periodontium have received less attention. Our investigation was aimed at evaluating the correlation between hormonal fluctuations and periodontal status in postmenopausal women from the profile of the Rafsanjan Cohort Study. Material and Methods. We used the data obtained from the profile of the Rafsanjan Cohort Study (RCS) as a part of the prospective epidemiological research studies in Iran (PERSIAN). The RCS includes 10,000 participants aged 35–70 years old. Among this population, the periodontal status data of 4143 women were available. Of these 4,143, the postmenopausal women were included in the study, and those who had a history of gingival treatment during the past 6 months were excluded from the study. Finally, 928 postmenopausal women were included in the present study. Periodontal status was assessed by measuring the clinical attachment loss, pocket depth, and bleeding on probing (BOP). Univariate and multivariate regression analyses were applied using three different models. Results The results showed that 53.2% of postmenopausal women had periodontitis. There were significant differences between the participants with and without periodontitis in brushing frequency and educational status (P < 0.05). After adjusting for all potential confounders, no correlation was found between hormonal fluctuations and periodontal status. Conclusion There was no correlation between hormonal fluctuations and periodontal status.
High Drug Capacity Doxorubicin-Loaded Iron Oxide Nanocomposites for Cancer Therapy

Magnetic nanoparticles (MNPs) have great potential in the drug delivery area. Iron oxide (Fe3O4) MNPs have demonstrated a promising effect due to their ferrimagnetic properties, large surface area, stability, low cost, easy synthesis, and functionalization. Some coating procedures are required to improve stability, biocompatibility, and decrease toxicity for medical applications. Herein, the co-precipitation synthesis of iron oxide MNPs coated with four types of primary surfactants, polyethylene glycol 2000 (PEG 2000), oleic acid (OA), Tween 20 (Tw20), and Tween 80 (Tw80), were investigated. Dynamic light scattering (DLS), ζ-potential, and transmission electron microscopy (TEM) techniques were used for morphology, size, charge, and stability analysis. Methylene blue reactive oxygen species (ROS) detection assay and the toxicity experiment on the lung adenocarcinoma A549 cell line were conducted. Two loading conditions for anticancer drug doxorubicin (DOX) on MNPs were proposed. The first one provides high loading efficiency (~90%) with up to 870 μg/mg (DOX/MNPs) drug capacity. The second is perspective for extremely high capacity 1757 μg/mg with drug wasting (DOX loading efficiency ~24%). For the most perspective MNP_OA and MNP_OA_DOX in cell media, pH 7.4, 5, and 3, the stability experiments are also presented. MNP_OA_DOX shows DOX pH-dependent release in the acidic pH and effective inhibition of A549 cancer cell growth. The IC50 values were calculated as 1.13 ± 0.02 mM in terms of doxorubicin and 0.4 ± 0.03 µg/mL in terms of the amount of the nanoparticles. Considering this, the MNP_OA_DOX nano theranostics agent is a highly potential candidate for cancer treatment.
Discrete Mixed-Integer Shooting (DMIS): Algorithm and Application to Plug-In Hybrid Electric Vehicle Energy Management Accounting for Fuel Cranking and Actual Powertrain Efficiency Maps

This article presents an algorithm for mixed-integer nonlinear optimal control problems (OCPs) formulated directly in discrete time. In our current application, we address the energy management of a plug-in hybrid electric vehicle (PHEV) seeking to achieve minimum trip fuel consumption under a terminal state-of-charge (SOC) equality constraint while avoiding powertrain efficiency map approximations in order to maximize its fuel economy (FE). An additional engine cranking state with a nonsmooth state and control transition cost is then incorporated to prevent undesired engine on/off behaviors. We pursue a single shooting-based numerical algorithm, motivated by the success of the computationally efficient Pontryagin’s Minimum Principle (PMP)-based single shooting in achieving similar FE results as dynamic programming (DP) for the power-split optimization problem without the additional engine cranking state shown in prior work. The Discrete Mixed-Integer Shooting (DMIS) algorithm, with costate backward-in-time propagation, is presented here, avoiding unstable shooting iterations that are typically encountered in PMP-based single shooting. When applying DMIS to solve the power-split problem with cranking fuel consideration, we show through simulation that it leads to better FE results than the PMP-based single shooting without the cranking state, thus demonstrating the effectiveness of the DMIS algorithm. Finally, experimental dynamometer test results with the model predictive powertrain controller solved by DMIS for minimum trip fuel consumption are presented and discussed, demonstrating its real-time execution and the cranking fuel reduction capability.
Body Composition Changes in College Athletes during the COVID-19 Lockdown

Background: In the spring of 2020, COVID-19 shocked the college sports world with athletes having seasons abruptly canceled and sent home under mandatory lockdown orders. Athletes and athletic performance staff had no idea when they would be back on campus or have access to on-campus athletics facilities. This situation caused substantial concern regarding potential adverse changes to athletic performance and body composition in the athletes. The purpose of this study is to assess how weight, muscle mass, and fat mass changed in collegiate athletes while they were prohibited from using on-campus athletic facilities due to the COVID-19 pandemic. Methods: Body weight, fat mass, and muscle mass were measured using bioelectrical impedance analysis as part of routine care for 77 collegiate athletes (n = 43 male, n = 34 female) pre-lockdown (Jan 2020) and shortly after their return to on-campus training (Aug/Sept 2020). 4 questions were asked to assess eating behavior and physical activity. Pre- and post-lockdown body composition data and survey data were analyzed using ANOVA and ANCOVA (SAS 9.4). To account for differences in body size, height was used to calculate Body Mass Index (BMI), Fat Mass Index (FMI), and muscle mass index (MMI) for assessing changes in weight, fat mass, and muscle mass, respectively. Results: No significant differences by sex in BMI or MMI were detected between pre and post lockdown. FMI changed according to sex, males lost FMI and females gained FMI. Conclusion: These data demonstrate potential sex differences in fat mass changes among college athletes during a mandatory absence from on-campus athletic facilities and in-person support from coaching and performance staff. Future research should determine whether future breaks - either anticipated or unanticipated-influence body composition and what the drivers of changes in body composition may be. Such research may help to develop sex-specific strategies for maintaining optimal body composition and athletic performance during extended breaks from structured athletic training.
Improving access to care and community health in Haiti with optimized community health worker placement

The national deployment of polyvalent community health workers (CHWs) is a constitutive part of the strategy initiated by the Ministry of Health to accelerate efforts towards universal health coverage in Haiti. Its implementation requires the planning of future recruitment and deployment activities for which mathematical modelling tools can provide useful support by exploring optimised placement scenarios based on access to care and population distribution. We combined existing gridded estimates of population and travel times with optimisation methods to derive theoretical CHW geographical placement scenarios including constraints on walking time and the number of people served per CHW. Four national-scale scenarios that align with total numbers of existing CHWs and that ensure that the walking time for each CHW does not exceed a predefined threshold are compared. The first scenario accounts for population distribution in rural and urban areas only, while the other three also incorporate in different ways the proximity of existing health centres. Comparing these scenarios to the current distribution, insufficient number of CHWs is systematically identified in several departments and gaps in access to health care are identified within all departments. These results highlight current suboptimal distribution of CHWs and emphasize the need to consider an optimal (re-)allocation.
Innovative optical method for sensing the nutritional stress in hydroponically cultivated plants

ABSTRACT Well-balanced nutrition is important for the successful cultivation of healthy plants. In this paper, we demonstrate a nondestructive optical method that can sense a deficiency of certain nutrients. The setup was tested on hydroponically grown Ocimum basilicum. The plants were subjected to nutrient deficiency by the exclusion of one of the essential elements (Fe, Mg, P, N) from the hydroponic solution. A control group of plants, fed by the balanced hydroponic solution, was also grown under the same conditions. The proposed method tracks and records the optical transmittance of the plants' leaves. All groups exhibit clearly defined day-night Circadian rhythms. When compared to the control group, the treated plants exhibited modified circadian rhythms of the optical transmission, suggesting an early indicator of the plants' stress. The condition of the plants under test was also assessed by the more common (destructive) methods such as: measurements of the determination of the photosynthetic pigment content, dray weight determination and the efficiency of PSII. Several biological parameters were observed, calculated and compared to the graphs of optical transmission dependence in real time. Presented results have demonstrated a significant potential of the proposed optical method for the early detection of plants' stress in hydroponic cultivation.
Is central pancreatectomy an effective alternative to distal pancreatectomy for low-grade pancreatic neck and body tumors: A 20-year single-center propensity score-matched case-control study

Backgrounds/Aims Central pancreatectomy (CP) is associated with a higher rate of postoperative pancreatic fistula (POPF), and it is less preferred over distal pancreatectomy (DP). We compared the short- and long-term outcomes between CP and DP for low-grade pancreatic neck and body tumors. Methods This was a propensity score-matched case-control study of patients who underwent either CP or DP for low-grade pancreatic neck and body tumors from 2003 to 2020 in a tertiary care unit in southern India. Patients with a tumor >10 cm or a distal residual stump length of <4 cm were excluded. Demographics, clinical profile, intraoperative and postoperative parameters, and the long-term postoperative outcomes for exocrine and endocrine insufficiency, weight gain, and the 36-Item Short Form Survey (SF-36) quality of life questionnaire were compared. Results Eighty-eight patients (CP: n=37 [cases], DP: n=51 [control]) were included in the unmatched group after excluding 21 patients (meeting exclusion criteria). After matching, both groups had 37 patients. The clinical and demographic profiles were comparable between the two groups. Blood loss and POPF rates were significantly higher in the CP group. However, Clavien-Dindo grades of complications were similar between the two groups (p = 0.27). At a median follow-up of 38 months (range = 187 months), exocrine sufficiency was similar between the two groups. Endocrine sufficiency, weight gain, SF-36 pain control score, and general health score were significantly better in the CP group. Conclusions Despite equivalent clinically significant morbidities, long-term outcomes are better after CP compared to DP in low-grade pancreatic body tumors.
Importance of Breed, Parity and Sow Colostrum Components on Litter Performance and Health

Simple Summary Colostrum quality and quantity can influence the growth, health, and survival of sow offspring, and can therefore influence sow productive performance. Colostrum quality can be affected by a multitude of factors; of these, the breed of the sows and its parity were investigated in the present study. The aim of the study was to identify the influence of sow breed and parity on colostrum components and to associate these with the survival, growth, and occurrence of diarrhoea of their litters. The results revealed that a more robust breed, such as Duroc, could have more colostral immunoglobulins (Igs) than the Large White and Landrace breeds. Gilts are characterised by a higher fat % and number of somatic cells (SCs), which are positively correlated to each other. Piglet survivability until weaning can increase with an increased quantity of IgA and SCs in the colostrum; piglet diarrhoea can decrease with an increased quantity of IgA. Increasing knowledge regarding swine colostrum composition and its relation to litter performance can help in designing new intervention strategies to improve the welfare and economic sustainability of pig rearing systems. Abstract The aims of this study were to investigate the effect of breed and parity on colostrum components, and to associate sow breed, parity, and colostrum components with survival, growth, and the occurrence of diarrhoea of their litters. In Experiment 1, 64 sows (Duroc = 13; Landrace = 17 and Large White = 34) were included. In Experiment 2, 71 sows with different parities (1 = 10; 2 = 16; 3 = 13; 4 = 12; ≥5 = 20) were included. The number (N) of live piglets, litter body weight (Experiment 1), and the occurrence of diarrhoea (Experiment 1) were recorded at farrowing, at 2–3 days of age, and at weaning. Colostrum was analysed for proximate composition, immunoglobulins (Igs), and somatic cell count (SCC). Stepwise regressions and ANOVA models were used to associate breed, parity, and colostrum components with litter performance. The Duroc breed had the highest IgG and IgA (p < 0.005). Gilts had a higher fat% and SCC (p< 0.0001); these compounds were positively correlated (r = 0.45). Increased IgA tended to increase the N of weaned piglets (p = 0.058) and reduce litter diarrhoea (p = 0.021). The SCC increased the N of weaned piglets (p = 0.031). Overall, this study confirmed that breed and parity can influence the colostrum composition and highlighted the key role of Igs and somatic cells in piglet health.