Miracle-dz/UniFAR-FTUs huggingface dataset:
Supply chain stakeholder pressure for the adoption of sustainable supply chain practices: examining the roles of entrepreneurial and sustainability orientations

Purpose This study examines the relationship between supply chain stakeholder pressure from customers and suppliers for the adoption of social and environmental sustainable supply chain management (SSCM) practices given the simultaneous conditional effects of both entrepreneurial orientation (EO) and sustainability orientation (SO). Design/methodology/approach The authors conducted a survey of US firms focused on their relationship with their top supplier or buyer by spend. This study used conditional process analysis to measure the relationship between stakeholder pressure and adoption of SSCM practices as well as the double moderation effects of EO and SO on this relationship. Findings The results show that both EO and SO simultaneously function as moderators of the effect of supply chain stakeholder pressure on the adoption of social and environmental SSCM practices. However, EO will only get firms so far in the adoption of SSCM practices. Once a strong SO takes effect, higher practice adoption ensues but the effect of stakeholder pressure weakens. Practical implications For those firms that have lower levels of SO, EO and supply chain stakeholder pressure are still essential drivers for the adoption of SSCM practice. The results of this study suggest that focal firms should work closely with suppliers to increase their levels of SO while also maintaining pressure for the adoption of SSCM practices. Originality/value This study shows the concurrent effect of two organizational level drivers on the adoption of SSCM practices, indicating that efforts in developing a strong SO are more likely to prepare firms for the adoption of SSCM practices.
Advances in the Diagnosis of Pancreatic Cystic Lesions

Pancreatic cystic lesions (PCLs) are a heterogenous group of lesions ranging from benign to malignant. There has been an increase in PCLs prevalence in recent years, mostly due to advances in imaging techniques, increased awareness of their existence and population aging. Reliable discrimination between neoplastic and non-neoplastic cystic lesions is paramount to ensuring adequate treatment and follow-up. Although conventional diagnostic techniques such as ultrasound (US), magnetic resonance imaging (MRI) and computer tomography (CT) can easily identify these lesions, assessing the risk of malignancy is limited. Endoscopic ultrasound (EUS) is superior to cross-sectional imaging in identifying potentially malignant lesions due to its high resolution and better imaging characteristics, and the advantage of allowing for cyst fluid sampling via fine-needle aspiration (FNA). More complex testing, such as cytological and histopathological analysis and biochemical and molecular testing of the aspirated fluid, can ensure an accurate diagnosis.
Educational technologies to guide pulmonary tuberculosis sputum collection: a systematic review

ABSTRACT Objective: To evaluate the contributions of educational technologies used during the guidelines for sputum collection from pulmonary tuberculosis. Method: Systematic review guided by Preferred Reporting items for Systematic Reviews with protocol registered in the database International Prospective Register of Systematic Reviews, with number CRD42020208162. The search was performed in the Cinahl, Scopus, PubMed, Web of Science, Embase, Lilacs, CENTRAL, CAPES, Proquest, OpenGrey databases and manual search in the reference list. The search, selection of studies, data extraction, and methodological evaluation using the Cochrane Risk-of-Bias tool were performed by two independent reviewers. Results: A total of 2,488 studies were evidenced, with seven being selected and analyzed, of which four used structured lectures; three, educational booklet; and one, an educational video, used alone or together, impacting the bacteriological confirmation of tuberculosis. The studies had a low risk of bias. Conclusion: Scientific evidence has shown that educational technologies contribute to increasing the quality, volume, and appearance of the sputum sample, which improves the bacteriological confirmation of the disease.
Influenza Vaccination Coverage among Multiple Sclerosis Patients: Evolution over Time and Associated Factors

Our objective was to determine the influenza vaccination rate in a Spanish cohort of multiple sclerosis (MS) patients. A retrospective cohort study was carried out. Patients who attended the MS unit of the Lozano Blesa Hospital of Zaragoza between January 2015 and 2020 were included. The variables were obtained by reviewing the specialized and primary care records. Associations between receiving the vaccine in each flu season and the other variables were analyzed using bivariate analysis and multiple logistic regression models. A total of 260 patients were studied, with a median age of 31 years at the time of diagnosis. A total of 62.3% (162/260) were women. Vaccination coverage ranged from 20.4% in the 2015–2016 and 2016–2017 seasons to 41.5% in the 2019–2020 season (p = 0.000). Having been vaccinated in the previous season (ORa: 16.47–390.22; p = 0.000) and receiving a vaccination recommendation from the hospital vaccination unit (ORa: 2.44–3.96; p < 0.009) were associated with being vaccinated. The coverage is in an intermediate position compared to other countries. It is necessary to improve the referral system of these patients to the hospital vaccination unit because the information obtained by this service contributed to higher vaccination rates.
Characterization of radar clutter as a spherically invariant random process

A statistical characterisation of clutter as a complex random process is needed in the design of optimum detection schemes. The paper considers modelling complex clutter as a spherically invariant random process (SIRP), namely assuming that its PDFs can be expressed as non-negative definite quadratic forms, a generalisation of a Gaussian process. Relevant properties of SIRPs are summarised, and shown to comply with basic requirements such as circular symmetry of the joint PDF of the in-quadrature components or, equivalently, the uniformity of the phase distribution. A constraint of admissibility must be imposed on the envelope distribution, but most commonly used envelope distributions, including Weibull, contaminated Rayleigh and K-distribution are shown to be admissible. Although a general SIRP is not ergodic, a characterisation of the clutter process as an SIRP scanned in the ensemble is finally proposed, which restores ergodicity. The interpretation of this model in the light of already proposed composite scattering models is also discussed.
From big bang cosmology to the cyclic universe in dynamic equilibrium

A cyclic model of a timeless universe in dynamic equilibrium is suggested in which the fundamental stage of physical processes is a three-dimensional non-local quantum vacuum defined by reduction-state processes of creation/annihilation of quanta which occur in correspondence to elementary energy fluctuations. It is shown in what sense this model implies the existence of symmetry between the energy of matter and energy of space and, consequently, of a cyclic transformation space-matter-space-matter. in the active galactic nuclei. It is concluded by demonstrating how this model of the cyclic universe in dynamic equilibrium allows us to resolve some important problems of the Standard Cosmological Model.
Association between Individual Norepinephrine Transporter (NET) Availability and Response to Pharmacological Therapy in Adults with Attention-Deficit/Hyperactivity Disorder (ADHD)

Background: The role of the norepinephrine transporter (NET) has received increased focus in recent studies on the pathogenesis of attention-deficit/hyperactivity disorder (ADHD). The predictive value for pharmacological treatment and its link to other health or social limitations has been little-studied. This follow-up research on adult patients with ADHD aimed to explore whether the therapy response and health and social impairments depend on baseline individual NET availability. Methods: Data were collected from 10 patients on personal, family and professional situations, mental and physical health and treatments received after baseline via online and telephone surveys and were compared to baseline data to evaluate treatment-related changes. Results: The majority of our ADHD patients did not show therapy responses but showed improvements due to pharmacological treatment. There was no evidence of relationships between pre-treatment NET availability and therapy response or health/social limitations. Conclusions: Pharmacological monotherapy was insufficient to promote symptom remission, especially for participants with extreme insufficiency in NET availability, but improved outcomes in academic and social functioning. Psychotherapy should be considered as an add-on to the standard treatment approach due to its positive outcome in reducing social limitations. The prognostic value of individual NET availability in predicting the response to therapy needs further studies with large sample sizes.
Tool Use in Horses

Simple Summary Tool use has not yet been confirmed in horses, mules or donkeys. As this subject is difficult to research with conventional methods, we used crowdsourcing to gather data. We asked equid owners and carers to report and video examples of “unusual” behaviour via a dedicated website, and we searched YouTube and Facebook for videos of equids showing tools. From 635 reports, including 1014 actions, we found 13 unambiguous cases of tool use. Tool use was associated with restricted management conditions in 12 of the 13 cases, and 8 of the 13 cases involved other equids or humans. The most frequent tool use, with seven examples, was for foraging, for example, equids using sticks to scrape hay into reach. There were four cases of tool use for social purposes, such as horses using brushes to groom others, just one case of tool use for escape, in which a horse threw a halter when it wished to be turned out, and one case of tool use for comfort, in which a horse scratched his abdomen with a stick. Equids therefore can develop tool use, especially when management conditions are restricted, but it is rare. Abstract Tool use has not yet been confirmed in horses, mules or donkeys. As this subject is difficult to research with conventional methods, we used a crowdsourcing approach to gather data. We contacted equid owners and carers and asked them to report and video examples of “unusual” behaviour via a dedicated website. We also searched YouTube and Facebook for videos of equids showing tool use. From 635 reports, including 1014 behaviours, we found 20 cases of tool use, 13 of which were unambiguous in that it was clear that the behaviour was not trained, caused by reduced welfare, incidental or accidental. We then assessed (a) the effect of management conditions on tool use and (b) whether the animals used tools alone, or socially, involving other equids or humans. We found that management restrictions were associated with corresponding tool use in 12 of the 13 cases (p = 0.01), e.g., equids using sticks to scrape hay within reach when feed was restricted. Furthermore, 8 of the 13 cases involved other equids or humans, such as horses using brushes to groom others. The most frequent tool use was for foraging, with seven examples, tool use for social purposes was seen in four cases, and there was just one case of tool use for escape. There was just one case of tool use for comfort, and in this instance, there were no management restrictions. Equids therefore can develop tool use, especially when management conditions are restricted, but it is a rare occurrence.
Clinical and Virological Response to Convalescent Plasma in a Chronic Lymphocytic Leukemia Patient with COVID-19 Pneumonia

The burden of COVID-19 remains unchanged for immunocompromised patients who do not respond to vaccines. Unfortunately, Omicron sublineages are resistant to monoclonal antibodies authorized in Europe so far, and small chemical antivirals have contraindications and toxicities that have not been studied in these patients. We report here the successful treatment of COVID-19 pneumonia lasting for 4 months after the transfusion of COVID-19 convalescent plasma (CCP) in a patient with severe immunosuppression due to both chronic lymphocytic leukemia and venetoclax treatment. The patient achieved a complete clinical, radiological and virological response after six transfusions (600 mL each) of high-titer CCP collected from triple-vaccinated and convalescent donors. This dramatic case adds to the mounting evidence of CCP efficacy in immunocompromised patients, provided that high-titer and large volumes are infused.
A Novel Computational Tool for the Fractional-Order Special Functions Arising from Modeling Scientific Phenomena via Abu-Shady–Kaabar Fractional Derivative

Recently, a generalized fractional derivative formulation, known as Abu-Shady–Kaabar fractional derivative, is studied in detail which produces satisfactory results that are consistent with conventional definitions of fractional derivative such as Caputo and Riemann-Liouville. To derive the fractional forms of special functions, the generalized fractional derivative is used. The findings demonstrate that the current findings are compatible with Caputo findings. In addition, the fractional solution to the Bessel equation is found. While modeling phenomena in engineering, physical, and health sciences, special functions can be encountered in most modeling scenarios related to electromagnetic waves, hydrodynamics, and other related models. Therefore, there is a need for a computational tool for computing special functions in the sense of fractional calculus. This tool provides a straightforward technique for some fractional-order special functions while modeling these scientific phenomena in science, medicine, and engineering.
Segmentation of Oral Leukoplakia (OL) and Proliferative Verrucous Leukoplakia (PVL) Using Artificial Intelligence Techniques

PVL (proliferative verrucous leukoplakia) has distinct clinical characteristics. They have a proclivity for multifocality, a high recurrence rate after treatment, and malignant transformation, and they can progress to verrucous or squamous cell carcinoma. AI can aid in the diagnosis and prognosis of cancers and other diseases. Computational algorithms can spot tissue changes that a pathologist might overlook. This method is only used in a few studies to diagnose LB and PVL. To see if their cellular nuclei differed and if this cellular compartment could classify them, researchers used a computational system and a polynomial classifier to compare OLs and PVLs. 161 OL and 3 PVL specimens in the lab were grown, photographed, and used for training and computation. Exam orders revealed patients' sociodemographics and clinical pathologies. The nucleus was segmented using Mask R-CNN, and LB and PVL were classified using a polynomial classifier based on nucleus area, perimeter, eccentricity, orientation, solidity, entropies, and Moran Index (a measure of disorderliness). The majority of OL patients were male smokers; most PVL patients were female, with a third having malignant transformation. The neural network correctly identified cell nuclei 92.95% of the time. Except for solidity, 11 of the 13 nuclear characteristics compared between the PVL and the LB showed significant differences. The 97.6% under the curve of the polynomial classifier was used to classify the two lesions. These results demonstrate that computational methods can aid in diagnosing these two lesions.
Olive Oil Phenolics and Platelets—From Molecular Mechanisms to Human Studies

Chronically activated, dysfunctional platelets mediate the progression of the majority of non-communicable diseases in a pleiotropic fashion. Antiplatelet therapy remains an attractive therapeutic means which however hasn’t reached the expected targets according to the promising preclinical studies. It is therefore obvious that the consumption of foods demonstrating antiplatelet activity may be a less drastic but on the other hand a more sustainable way of achieving daily antiplatelet therapy, either alone or in combination with antiplatelet drugs. Olive oil is probably the main cardioprotective component of the Mediterranean Diet according to the results of observational and dietary intervention studies. Among all phytochemicals of olive oil, its unique phenolics seems to be responsible for the majority of its cardioprotective properties. This review article aims to highlight the platelet modulating roles of olive oil polyphenols, trying to critically assess whether those properties could partially explain the cardioprotective role of olive oil. The cellular and animal studies clearly show that extra virging olive oil (EVOO) phenolics, mainly hydroxytyrosol, are able to inhibit the activation of platelets induced by several endogenous agonists and pathologies. However, the outcomes of the pre-clinical studies are difficult to be translated to humans mainly because the dosages and the chemical forms of the phenolics used to these studies are much higher and different to that found in human circulation. Despite the heterogeneity of the few human trials on the field so far, the results are promising showing that EVOO can exert antiplatelet actions in real, acute or long-term, trials and at least part of this antiplatelet action can be attributed to the phenolic content of EVOOs. Although we clearly need better, well-powered studies to give certain answers on this field the antiplatelet properties of olive oil phenolics is a promising, emerging mechanism which may explain some of the health properties of EVOO and the Mediterranean Diet.
EXPLORING STUDENTS’ USE OF E-RESOURCES IN THE E-LIBRARIES OF THE PUNJAB

This study was conducted to explore students’ use of E-resources in the E-libraries of the Punjab by using Unified Theory of Acceptance and Use of Technology (UTAUT) model. The use of e-resources included; performance expectancy, effort expectancy, social influence, facilitating condition, and behavioral intention to use the e-resources. Students’ access to e- collection, ease of access, frequency of using resources, and problems associated with access to e-resources was also explored. A quantitative survey was conducted using a descriptive research design. All 20 e-libraries of the Punjab were the population of this research. Six e-libraries were selected randomly as a sample. The sample was selected from the list of users registered in each library using a proportionate sampling technique. The total number of participants was 250. A self-developed questionnaire with 26 items and a checklist having 8 items, was used to collect the data. To analyze the data descriptive statistics was used. The findings of this study showed that students agreed that they were getting advantages from these e-libraries and these e-libraries were very helpful in their study. They could easily and more efficiently do their work by using and accessing e-library resources. These e-libraries were especially beneficial for those students who did not afford laptops. It is suggested that the government should increase the number of these e-libraries and these libraries should be established in all big cities of Pakistan. The library staff should focus on resolving the problems which students are facing, like a shortage of computers and off-library access.
Examining the Asymmetric Effects of Third Country Exchange Rate Volatility on Trade between the US and the EU

This paper aims to examine the symmetric and asymmetric effects of third country exchange rate volatility on the trade flow between the US and EU from January 2003 through March 2021. The monthly disaggregated data of the top twelve export and import industries are the sample frame. We find that separating increased volatility from declines and introducing a nonlinear adjustment to the volatility shows a more significant outcome than symmetric analysis. Different industries carry distinctive behaviors regarding exchange rate risk, and the third country effect plays a vital role in trade. Moreover, increased CNY/USD real exchange rate volatility increases bilateral trade between the US and EU.
Exploring Human Capital Training Trends Using Bibliometric Analysis

A workforce is so called human capital is an asset to country, organization and company. An effective investment in human capital can be seen in the development of innovation, productivity, and competitiveness of a country. This topic of human capital training is important because most developing countries human capital investment is done through training and education. It is believed that sustainable human capital investment in training and education is vital to ensure a high economic growth and development. Thus, the objective of this study is to perform bibliometric analysis on scientific literature published in the field of human capital training and education. Scopus database was used to gather all related literature on human capital training and education. The methodology used for this study apart from SPSS and Microsoft Excel software, we also utilise Publish or Perish software to integrate the data and perform simple analysis before using VOSviewer to perform data visualisation. The main finding for this research indicates a total of 1,218 documents were retrieved based on the keyword search results and 10 articles were excluded. The study of human capital training and education begins 53 years ago to be exact in 1968. Most articles were written in English and published in journals and conferences articles. Majority of these articles were in the Business, Management and Accounting fields. The bibliometric analysis presents the advancement of the scientific literature on human capital training and education and highlights the area of interest where future researchers could explore. The area for future research in human capital development including education,
Nicotine Exerts Cytotoxic Effects in a Panel of Healthy Cell Lines and Strong Irritating Potential on Blood Vessels

The use of tobacco products is a major global public health issue, as it is the leading cause of preventable death worldwide. In addition, nicotine (NIC) is a key component of electronic and conventional cigarettes. Although nicotine’s addictive potential is well known, its health effects are not entirely understood. Thus, the main objective of the present study was to evaluate its toxicological profile both in vitro, at the level of three healthy cell lines, and in ovo, at the level of the chorioallantoic membrane. Five different concentrations of nicotine were used in keratinocytes, cardiomyocytes, and hepatocytes for the purpose of evaluating cell viability, cell morphology, and its impact on nuclei. Additionally, the hen’s egg test on the chorioallantoic membrane (HET-CAM) method was used to assess the biocompatibility and irritant potential of the chorioallantoic membrane. Across all cell lines studied, nicotine was proven to be significantly damaging to cell viability, with the highest concentration tested resulting in less than 2% viable cells. Moreover, the morphology of cells changed dramatically, with alterations in their shape and confluence. Nicotine-induced cell death appears to be apoptotic, based on its impact on the nucleus. In addition, nicotine was also found to have a very strong irritating effect on the chorioallantoic membrane. In conclusion, nicotine has an extremely strong toxicological profile, as demonstrated by the drastic reduction of cell viability and the induction of morphological changes and nuclear alterations associated with cellular apoptosis. Additionally, the HET-CAM method led to the observation of a strong irritating effect associated with nicotine.