Miracle-dz/UniFAR-FTUs huggingface dataset:
Isolated Central Nervous System Metastasis From Neuroendocrine Carcinoma of the Cervix Without Pulmonary Metastasis

Neuroendocrine carcinoma of the cervix (NECC) accounts for 2% of all cervical cancers. Brain metastasis is rare, with few cases described in the literature, and is usually associated with preceding pulmonary metastasis. We describe an additional case of isolated brain metastasis without pulmonary metastasis from NECC and reflect on unique management. A 37-year-old woman with a history of NECC presented with severe headache post-total hysterectomy with pelvic lymph node dissection. The computed tomography (CT) scan demonstrated obstructive hydrocephalus with several intra-axial lesions located in the pineal region, left cerebellar hemisphere, and left frontal operculum. A right frontal ventriculostomy was initially placed to relieve the hydrocephalus. CSF was sent for cytology but was unrevealing. Due to the degree of brainstem compression and the need to obtain a pathologic diagnosis, a posterior fossa craniotomy for the removal of the lesion was performed. Histopathology demonstrated small blue cell tumors positive for neuroendocrine markers consistent with neuroendocrine carcinoma of the cervix. Resection of additional metastasis was not recommended. An endoscopic third ventriculostomy (ETV) was then performed in order to remove the ventriculostomy with success. The patient was then referred to radiation oncology and received whole-brain radiotherapy (WBRT) for a total of 30 Grays (3000 cGy) over 10 fractions. Interval imaging demonstrated complete resolution of the pineal and left frontal lesions. The patient was symptom-free for approximately three months. She then presented with paraplegia consistent with follow-up imaging of her neuraxis, demonstrating drop metastasis in her cervical, thoracic, and lumbar spine. Spinal radiation was given with partial recovery in upper extremity function, however, lower extremity function did not recover. The patient was then transferred to palliative care. There are no guidelines on NECC brain metastasis management. Brain metastasis is associated with reduced longevity. NECC has a propensity for early dissemination and treatment failure. ETV is preferred over ventriculoperitoneal shunting in cases with obstructive hydrocephalus, as it may reduce the risk of tumor seeding. Retrospectively, our patient may have benefitted from upfront craniospinal radiation.
Quality evaluation of musk melon seeds flour and jackfruit seeds flour for bakery products development

Bakery products are influenced by many factors including the ingredients used and the processing environment. The Musk melon and Jackfruits seed were separated and grinded. The analysis of musk melon flour, jackfruit flour and wheat flour gave the proximate composition and the results obtained. Jack fruit and musk melon seed flour cake was prepared and analysed with chemical (moisture, crude fibre, ash, protein, fat and carbohydrate contents) and sensory evaluation (manually with colour, flavour and overall acceptability) showed that jackfruit seed flour composite cake is very good and everybody like it.
Antibiotic sensitivity pattern of bacteria isolated from Nigerian currencies (Naira) circulating in some hospitals of Kano metropolis, Kano state, Nigeria

Microbial contamination of fomites such as currency notes is of public health concern as contaminated materials might act as vehicle for the transmission of pathogenic and drug resistant organisms. The aim of this study was to evaluate antibiotic susceptibility profile of bacteria isolated from Nigerian currencies circulating in some hospitals of Kano metropolis. Four hundred paper currency notes of all denominations obtained from three hospitals (Hasiya Bayero pediatrics hospital, Murtala Mohammad specialist hospital and Aminu Kano Teaching Hospital) and school environment (Bayero university Kano) were investigated. The samples were all screened for bacterial pathogens and some common nosocomial pathogens using standard microbiological procedures. Antibiotic susceptibility testing was done using disc diffusion method to detect the presence of resistant isolates including multidrug resistant organisms (MDR) and methicillin resistant Staphylococcus aureus (MRSA). The results of the study revealed that 84.7% of currencies were contaminated with pathogenic organisms. Bacteria isolated from currencies circulating in hospital were more resistant to antibiotics than non hospital source isolates (p 0.05) for MRSA from hospital and non hospital currencies respectively. Staphylococcus aureus, S. epidermidis, Escherichia coli, Bacillus species, Streptococcus species, Proteus species, Klebsiella spp, Salmonella spp and Pseudomonas aeruginosa were the most frequent isolated bacteria. Ampicillin, cotrimoxaxole, and amoxicillin/clavulanate showed high levels of inactivity. Ciprofloxacin had the greatest activity (40% to 100%) against the isolates. The study revealed that Currency notes circulating in hospital are highly contaminated with potentially pathogenic bacteria including drug resistant nosocomial pathogens, MRSA and MDR organisms. Measures should therefore be employed to ensure the safety of currency handlers in the hospital. Key words: Antibiotic, Sensitivity pattern, Bacteria, Nigerian Currencies, Hospitals
The Effect of Heparin on In Vitro Stimulated Platelet Aggregation by Elective Percutaneous Coronary Intervention

Background: The aim of the present study was to investigate the effects of heparin on in vitro stimulated platelet aggregation by elective percutaneous coronary intervention Methods: Thirty elective percutaneous coronary angioplasty (PTCA) patients were included in the present study. The patients were administered heparin as anticoagulant agent during PTCA. Two blood samples were obtained during the intervention before and 10 minutes after heparin bolus and stimulated platelet aggregation responses were investigated. Results: The difference in platelet aggregation response to adenosine diphosphate (ADP) before and after unfractionated heparin (UFH) was statistically significant (p<0.05). The differences in platelet aggregation responses to collagen, to epinephrine, and to ristocetin before and after UFH were not statistically significant (p>0.05). Conclusion: Heparin increases in vitro platelet aggregation stimulated with ADP in elective PTCA patients. This finding might explain the prothrombotic tendency of heparin, however further investigations are needed.
Long-Run Environmental Accounting in the US Economy

This paper estimates an augmented measure of national output inclusive of environmental pollution damage in the US economy over a 60-year period. The paper reports two primary findings. First, air pollution intensity declined precipitously from the 1950s to the modern era. Air pollution damage comprised roughly 30% of output in the post–World War II economy, declining to under 10% in 2016. Second, accounting for pollution damage significantly affects growth rates. Prior to the passage of the Clean Air Act in 1970, gross domestic product outpaced environmentally adjusted value added (EVA), defined as GDP less air pollution damage. Following passage of the act, EVA grew more rapidly than GDP. Macroeconomic and environmental policies, as well as the business cycle, appreciably affect damages and EVA growth.
Microorganism Distribution that Causes Abortionin Females of Fallujah City

The research included the study of microbiological content in the reproductive system and urinary tractinfections for abortions cases in the city of Fallujah. For this purpose, 121 swabs were taken, including50 swabs of the genital system (27 Vaginal and 23 Endo cervical swabs) and 71 swabs of urine. The resultrefer to that only 27 samples gave negative bacterial growth, while the other 94 samples showed growthof more than one species of bacteria on different media. The bacterial population isolated from the urinewas highest (81.7%), followed by vagina (74.1%) and the endo cervical (69.6%%). The results showedthat the ratios of the isolated bacterial samples were Escherichia coli (54.4%), Streptococcus agalactiae(17%), Staphylococcus aureus (12%), Klebsiella (8.5%), Pseudomonas aeruginosa (5.3%), Proteus (1%)and Candida albicans (1%). The E. coliwas the most common type bacterial isolates.Antibiotic sensitivitytests against 24 antibiotics were reveal that bacteria Escherichia colihave multiple resist against differentantibiotics, most isolates were highly resistant to Aztroenam followed by cefotaxime and ciproflaximerespectively, while their resistance to other antibiotics varied.The results also showed that Proteus whichisolated from urine samples and Candida albicans which isolated from vaginal specimens were the lowestpercentage, where only one isolate was obtain for each and the Candida abicans were resistant to all ofdifferent antibiotics used in this study.
Breeding for Resistance to Drought: A Case in Sorghum (Sorghum bicolor (L.)Moench)

Drought tolerance in sorghum was estimated in several ways: evaluation of grain yield under drought, the stability of yield, rate and duration of grain fill, seed weight, stay green and associated traits. Cultivars that tolerate pre-flowering water deficit are advantageous for the reason that yield components such as stand, tiller number, the number of heads, and especially the number of seed per head are determined during this period. Green leaf area at maturity is used as an indicator of post-anthesis drought resistance in sorghum breeding programs. For a successful selection of sorghum for drought resistance, the presence of considerable magnitude of variability in the available germplasm is a prerequisite. There is a positive correlation between drought tolerance and root length in sorghum. Moreover, water stress at seedling stage significantly affects the root to shoot ratio that seedling under water stress cause an increase in root length with a reduced diameter. In addition, numerous seedling traits have been suggested as important relative to drought tolerance including root weight, lateral root number and root-toshoot ratios. Therefore, the root to shoot ratio and its characteristics can be an indication of selection criteria for sorghum in respect of drought resistance. Molecular markers linked to QTL for drought tolerance could be used in increasing efficiency of breeding efforts to select sorghum germplasm with enhanced drought tolerance once these markers are identified through carefully monitored characterization of appropriate germplasm under stress conditions. Therefore, in this study the scientific results were evaluated and summarized.
Thirty-Five Years of Thyme: A Tale of Two Polymorphisms Why so many females? Why so many chemotypes?

Genetic polymorphisms that have readily discernible effects on phenotype provide model systems for the study of the evolutionary dynamics of natural populations. Some of the best examples of such polymorphisms, such as shell color and banding pattern in Cepaea nemoralis (Jones et al. 1977), industrial melanism in Biston betularia (Kettlewell 1973), mimetism in swallowtail butterflies (Turner 1977), and heterostyly in plants (Barrett 1992), illustrate the general importance of polymorphic variation. A consistent theme in studies of genetic polymorphism is that variations in the abundance of different morphs are common. Examinations of the basis of such variations have produced much information on the relative
Assessment of Morpho-Physiological, Yield and Yield Attributing Traits Related to Post Anthesis Drought in Wheat Genotypes Under Rainfed Condition in Rampur, Chitwan

This is an open access article & it is licensed under a Creative Commons Attribution Non-Commercial 4.0 International (https://creativecommons.org/licenses/by-nc/4.0/) A set of twenty wheat (Triticum aestivum L.) genotypes was evaluated to assess morpho-physiological, yield and yield attributing traits related to post-anthesis drought in wheat genotypes under rainfed condition in a Randomized completely block design with three replications at research farm of Faculty of Agriculture, Rampur, Chitwan, during winter season of 2016/2017. The result revealed highly significant genotypic effects for number of tillers per m area, plant height, spike length, number of grains per spike, weight of grains per spike, 1000 kernels weight, days to booting, days to heading, days to anthesis, days to flag leaf senescence, days to maturity, SPAD meter reading, peduncle length, grain filling duration and reproductive growth period. Significant genotypic effects were found for grain yield, biological yield and harvest index and an array of variation was found among the genotypes for each trait. But non-significant genotypic effect was found for canopy temperature depression. WK2373 gave highest grain yield kg/ha (3035 kg/ha) and biomass yield kg/ha (8080 kg/ha). This study presented WK2373, WK2379, WK2380, WK2386, WK2388, WK2383, WK 2378 and WK1481 the best genotypes governing different valuable traits. These potential genotypes for valuable traits found in different clusters. Crossing genotypes belonging to different clusters could maximize the opportunities for transgressive segregation as there is a higher probability that unrelated genotypes would contribute unique desirable alleles at different loci. Therefore, this study can help breeders to increase genetic diversity by selecting materials of divergent parentage for crosses, thereby reducing vulnerability to diseases and climate changes.
CatARact: Simulating Cataracts in Augmented Reality

For our society to be more inclusive and accessible, the more than 2.2 billion people worldwide with limited vision should be considered more frequently in design decisions, such as architectural planning. To help architects in evaluating their designs and give medical personnel some insight on how patients experience cataracts, we worked with ophthalmologists to develop the first medically-informed, pilot-studied simulation of cataracts in eye-tracked augmented reality (AR). To test our methodology and simulation, we conducted a pilot study with cataract patients between surgeries of their two cataract-affected eyes. Participants compared the vision of their corrected eye, viewing through simulated cataracts, to that of their still affected eye, viewing an unmodified AR view. In addition, we conducted remote experiments via video call, live adjusting our simulation and comparing it to related work, with participants who had cataract surgery a few months before. We present our findings and insights from these experiments and outline avenues for future work.
Invertebrate community structure and herbivory in a tropical rain forest canopy in Puerto Rico following Hurricane Hugo.

The effect of hurricane disturbance on canopy invertebrate communities was studied at the Luquillo Experimental Forest in Puerto Rico. Invertebrate community structure and herbivory were compared among tree species co-occurring in intact forest (standing trees) and canopy gaps. Foliage-bearing branches were collected using a long-handled insect net fitted with a closeable plastic bag. Invertebrates were tabulated and foliage was dried, weighed, and measured for area missing. Lepidoptera, predaceous beetles, and decomposers were significantly more abundant in standing trees; whereas, some sap-sucking arthropods were more abundant in canopy gaps, indicating that these taxa responded to changes in microclimate and/or host condition resulting from disturbance. Herbivory (estimated as leaf area missing) and numbers of several taxa differed significantly among tree species, likely reflecting host preferences based on foliage nutritional quality. Species diversity and the gradient of disturbance may have masked disturbance effects.
The impact of a date for understanding the importance of Homo naledi

We have recently described a new hominin species, Homo naledi, of unknown geological age. This provides a unique opportunity to present evolutionary hypotheses that will be tested when a date becomes available. We outline three possible scenarios that may apply to this species, exploring the implications of geological age for understanding its role in human evolution. The phylogenetic placement of H. naledi does not depend upon its geological age, but other aspects of the hominin record do.
Retrospective single-center analysis of the reasons and serious complications of peritoneal-related peritonitis in patients with end-stage renal disease undergoing peritoneal dialysis treatment

Abstract Introduction. Peritonitis is still a serious complication of peritoneal dialysis (PD). Consequences of peritonitis can be severe. The most severe are peritoneal dialysis discontinuation and patient’s death. In majority, peritonitis is bacterial in the origin. Mainly there is a gram-positive infection, less commonly gram-negative one. Some peritonitis are culture-negative, because of former antibiotics use. In minority, fungal, tuberculous or even viral peritonitis are observed. Aim. The aim of the present study is to analyze the number, origin and serious complications of peritoneal-related peritonitis cases found in our PD center. Material and methods. We performed a retrospective five-years evaluation of medical records. The total number of peritonitis episodes was 56 cases, underwent by 30 adult patients on chronic peritoneal dialysis. Peritonitis was diagnosed according to ISPD recommendations. Causes and serious complications of peritoneal-related peritonitis were analyzed in every single year. Etiology of peritonitis was classified on the basis of the result of effluent dialysate culture as: gram-positive, gram-negative and culture negative. Peritoneal dialysis discontinuation or patient’s death were defined as serious complications. Results. Among 56 cases of peritoneal-related peritonitis 44.6% were gram-positive, 26.8% gram-negative and 28.6% culture-negative. No fungal or tuberculosis peritonitis were found. Because of the peritonitis complications in the evaluated period, six patients discontinued peritoneal dialysis and were switched to hemodialysis (20%), two others died (6.7%). Conclusion. The further improvement in peritonitis’ causes identification and treatment is needed in order to reduce number of serious complications in our medical center.
Appetite and food consumption in the sea urchin Echinus esculantes L.

The importance of food intake due to sense of hunger (‘appetite’) and ‘social feeding’ in governing the rate of food intake was studied experimentally. The role of the degree of filling of the gut and the turnover time for food is discussed. Mean individual maximal food intake rate following 10 days of starvation was 2.8 g wwt Laminaria saccharina per 12 hours, decreasing smoothly within 36 hours to 0.4 g wwt per 12 hours (‘standard food intake’). Following 36 hours starvation, maximal food intake rate was again reached, giving a turnover time for food of 36 hours, and a voluntary food intake of 85 % of maximal consumption. In social feeding the same pattern was recorded, although maximal food intake rate was somewhat lower. The standard food intake was similar to that of the individual experiments, indicating that the maintenance of the standard energy requires a continuous intake of food.
Expression of Matrix Metalloproteinases in Marek'S Disease Tumours

Marek's disease is an important lymphoproliferative neoplasm of chickens, caused by oncogenic strains of herpes virus. Visceral lymphomas and invasion of both central nervous tissues and peripheral nerves by lymphoid cells are common findings. Matrix metalloproteinases (MMPs) are a group of enzymes responsible for extracellular matrix degradation and tumour metastases. The localisations of MMPs in tumour cells were evaluated immunohistochemically. As a result, positive reactions for MMP-9 and MMP-2 enzymes were found in the lymphoid tumour cells. These enzymes may take part in the pathogenesis of Marek's disease causing extracellular matrix degradation and metastasis.
Growth, yield and quality of ridge gourd as influenced by integrated nutrient management in coastal region of Maharashtra

A field experiment was conducted during Kharif-2016 to study the “Effect of integrated nutrient management on growth, yield and quality of ridge gourd. ” at Central Experiment Station, Wakawali, in Coastal region of Maharashtra. There were eight treatment combinations replicated thrice in a randornized block design. The result of the experiment showed that the growth, yield and quality of ridge gourd was significantly increased with integrated use of manure, fertilizers and bio-fertilizer. Among the various treatment tried, the treatment receiving an integration of manure, fertilizers and bio-fertilizer viz. 50 per cent RDN + 50 per cent N through poultry manure + P and K + Azotobacter @ 250 g 10 kg seed inoculation was significantly superior and recorded maximum growth parameters, yield and quality of ridge gourd. However, the treatment consisting 50 per cent RDN + 50 per cent N through vermicompost + P and K + Azotobacter @ 250 g 10 kg seed was at par with the earlier treatment in respect of above characters. On the basis of the results obtained during present investigation, it was observed that integrated use of 50 per cent RDN + 50 per cent N through poultry manure + P and K + Azotobacter @ 250g 10 kg seed is essential for improving growth parameter, yield and quality of ridge gourd grown in coastal region of Maharashtra.
Intertidal meiofaunal communities in relation to salinity gradients in the Ba Lai river, Vietnam

In order to reveal the characteristics of meiofaunal communities (MC) (specifically freshwater meiofauna) and its relationship with salinity gradients, meiofauna samples were collected in September 2015 in Ba Lai river (BLR), Mekong river, Vietnam. A total of 14 meiofaunal taxa were identified. The most dominant group was Nematoda, followed by Nauplii and Rotifera. The MC (specifically nematodes) in BLR were characterized by high abundances and diversities. The characteristics of MC in the downstream site (marine habitats) may be a considerable difference from those in the upstream site (fresh habitats). Abundances and diversities of nematode communities in the downstream site were much higher than observed in the upstream site, especially for abundances. Regarding MC, their abundance in the downstream site was also considerably higher than those in upstream site, whereas their diversity in the downstream site was lower than estimated in the upstream site. Furthermore, the Ba Lai dam (BLD) has the ability to change salinity gradients in BLR, while MC were a strong correlation with salinity. Therefore, the MC and their correlation with environmental variables can be considered as a good tool for the effects of dams on river’s ecosystems. Để xác định các đặc điểm của quần xã động vật đáy cỡ trung bình (đặc biệt là nhóm nước ngọt) và mối liên hệ giữa chúng với độ mặn, mẫu động vật đáy được thu thập vào tháng 09 năm 2015 trên sông Ba Lai, thuộc hệ thống sông Mekong, Việt Nam. Tổng cộng 14 nhóm động vật đáy được ghi nhận, ưu thế nhất là Nematoda, sau đó là Nauplii và Rotifera. Quần xã động vật đáy trên sông Ba Lai có mật độ và đa dạng cao và đặc điểm nhóm nước ngọt (trong đập Ba Lai) khác biệt với nhóm nước mặn (ngoài đập). Mật độ và đa dạng của nhóm Nematoda ngoài đập cao hơn trong đập. Trong khi đó, đa dạng quần xã động vật đáy trong đập cao hơn bên ngoài, mật độ thì ngược lại. Ngoài ra, đập Ba Lai làm biến đổi độ mặn trên sông Ba Lai, trong khi độ mặn có tương quan chặc chẽ với quần xã động vật đáy. Cụ thể, mật độ, đa dạng của quần xã tuyến trùng và mật độ của quần xã động vật đáy cỡ trung bình có tương quan thuận với độ mặn. Ngược lại, độ đa dạng quần xã động vật đáy cỡ trung bình có tương quan nghịch với độ mặn. Cho nên, quần xã động vật đáy có thể sử dụng làm chỉ thị cho tác động của đập chắn lên hệ sinh thái thủy vực.