Miracle-dz/UniFAR-FTUs huggingface dataset:
The interaction between grain boundary and tool geometry in nanocutting of a bi-crystal copper

Anisotropy is one central influencing factor on achievable ultimate machined surface integrity of metallic materials. Specifically, grain boundary has a strong impact on the deformation behaviour of polycrystalline materials and correlated material removal at the microscale. In the present work, we perform molecular dynamics simulations and experiments to elucidate the underlying grain boundary-associated mechanisms and their correlations with machining results of a bi-crystal Cu under nanocutting using a Berkovich tool. Specifically, crystallographic orientations of simulated bi-crystal Cu with a misorientation angle of 44.1° are derived from electron backscatter diffraction characterization of utilized polycrystalline copper specimen. Simulation results reveal that blocking of dislocation motion at grain boundaries, absorption of dislocations by grain boundaries and dislocation nucleation from grain boundaries are operating deformation modes in nanocutting of the bi-crystal Cu. Furthermore, heterogeneous grain boundary-associated mechanisms in neighbouring grains lead to strong anisotropic machining behaviour in the vicinity of the grain boundary. Simulated machined surface morphology and machining force evolution in the vicinity of grain boundary qualitatively agree well with experimental results. It is also found that the geometry of Berkovich tool has a strong impact on grain boundary-associated mechanisms and resultant ploughing-induced surface pile-up phenomenon.
Educating a health service workforce about dementia: a qualitative study

Purpose People who are living with dementia are core health service users but there are ongoing concerns about the quality of their care and the need for improved education of healthcare staff. This paper reports on a qualitative study that investigated staff perspectives of an ethnodrama (‘Barbara’s Story’) which was used to educate an entire health service workforce and promote a person-centred approach to care. Design/Methodology/Approach The study used a qualitative, longitudinal design with focus groups held with clinical (nurses, allied health professionals, medical) and non-clinical staff. In Phase 1 there were 10 focus groups (n=67 participants) and one individual interview. In Phase 2 there were 16 focus groups (n=77 participants) and three individual interviews. Findings Barbara’s Story raised awareness of dementia, engaged staff emotionally and prompted empathetic responses and improved interactions. The project’s senior leadership, whole organisation and mandatory approach were well-supported, with a perceived impact on organisational culture. The project helped to embed practice developments and initiatives to support person-centred care. Barbara’s story is now well integrated into the organisation, thus supporting sustainability. Originality/value Whilst there are increasing resources for educating about dementia, there are fewer evaluations, particularly for large-scale initiatives, and there is a lack of focus on long-term effects. The study findings indicate that education about dementia can be delivered to a whole work force in a sustainable manner, to prompt empathy, raise awareness, support person-centred care and impact on individual behaviour and organisational culture.
PENGARUH KEPEMIMPINAN DAN PENGEMBANGAN SUMBER DAYA MANUSIA TERHADAP KEPUASAN KERJA, MOTIVASI KERJA, DAN KINERJA KARYAWAN BANK SULSELBAR

This study aims to explain the effect of leadership and human resource development on job satisfaction, job motivation and employees performance. Analysis by using Structural Equation Modeling (SEM) with alpha 5% to test the significance of research variable. The data were taken from all Bank Sulselbar employees using cluster random sampling technique. The total respondents were 184 respondents. Questionnaire (main instrument), interview, observation, and documentary were used in collecting the data. Results of analysis (at significance level of 5%) showed that: 1) leadership has a significant effect on job satisfaction, 2) human resource development has a significant effect on job satisfaction, 3) leadership has a significant effect on job motivation, 4) human resource development has a significant effect on job motivation, 5) leadership has a significant effect on employee performance, 6) human resource development has a significant influence employee performance, 7) job satisfaction has a significant effect on job motivation, 8) job satisfaction has a significant effect on employee performance, and 9) job motivation does not significantly affect on employee performance.
Acquisition of Cancer Stem Cell Behaviour Plays a Role in Drug Resistance to Combination Chemotherapy and Prognosis in Head and Neck Cancer

Objective: Head and Neck Squamous Cell Carcinoma (HNSCC) demonstrate an exceptional initial response to induction chemotherapy; nevertheless, loco-regional relapse is widespread and not clearly understood. In this study, we investigated the role of Cancer Stem Cells (CSCs) in mediating chemo resistance using patient cohorts and cell line models. Methods: Profiling of CSC markers was carried out in primary untreated (Cohort I, N=33) and post treatment recurrent (Cohort II, N=27) HNSCC patients by Quantitative PCR (Q-PCR) and Immunihistochemistry (IHC). The prognostic significance of these markers was assessed by ROC curves and logistic regression analyses. The stem cell related behaviour of the drug resistant TPFR cell lines was assessed by the expression of CSC markers and other properties such as self-renewal, migration and tumorigenicity. Results: Post-treatment recurrent patients showed an over-expression of CSC markers (CD44, ABCG2 and NOTCH1) compared to the treatment naive cohort. Additionally, CD44 (p=0.028) and ABCG2 (p=0.019), in combination, were poor prognosticators (AUC 0.76). The resistant cell lines (Hep-2 TPFR and CAL-27 TPFR) were further characterized to delineate the role of CSCs in drug resistance. Analogous to the patients, these cells showed an enrichment of CD44+ cells accompanied by an increased spheroid formation (p<0.005) and migratory capacity (p<0.05). The up regulation of CSC markers (CD133, BMI and NOTCH1) and their resistance-mediating targets such as drug transporters and survival/anti-apoptotic pathways suggested possible causal mechanisms. Furthermore, the higher clonogenic survival in the presence of cisplatin (p<0.05) signifying an increased self-renewal capacity with drug resistance. The Hep-2 TPFR (102 cells) also showed an increased tumorigenicity (2/3; 9.5-fold increase in tumor burden) as compared to the parental (1/3; 6-fold). Conclusion: Our findings suggest that TPF combination chemotherapy enriches the resident cache of CSCs, ultimately leading to drug resistance. Consequently, in a sub set of patients, these drug resistant CSCs might contribute towards disease relapse/recurrence.
Insight into the Boundary Layer Flows of Free Convection and Heat Transfer of Nanofluids over a Vertical Plate using Multi-Step Differential Transformation Method

This paper presents an insight into the boundary layer of free convection and heat transfer of nanofluids over a vertical plate at very low and high Prandtl number. Suitable similarity variables are used to convert the governing systems of nonlinear partial differential equations of the flow and heat transfer to systems of nonlinear ordinary differential equations which are solved using multi-step differential transformation method. The approximate analytical solutions are verified with numerical solutions. From the parametric studies, it is observed that the velocity and temperature of the nanofluid decreases and increases, respectively as the Prandtl number and volume-fraction of the nanoparticles in the base fluid increase. Also, the decrease in velocity and increase in temperature are highest in lamina shaped nanoparticle followed by platelets, cylinder, bricks and sphere shaped nanoparticles, respectively. Using a common base fluid to all the nanoparticle type, it is observed that the decrease in velocity and increase in temperature are highest TiO2 followed by CuO, Al2O3 and SWCNTs nanoparticles, in that order. The present study will enhance the understanding of free convection boundary-layer problems.
Syringomyelia

conditions. He contrasts his position with that of philosopher Daniel Callahan, who considers “natural limits” t o health care by age-based cutoffs. Loewy specifically takes issue with Callahan, since age alone has no functional relevance. At the difficult interface between the experimental and the therapeutic, Loewy advocates social decisions that draw limits for interventions with little likelihood of success, in order to provide for the basic needs of the wider public. What Loewy does not fully consider is how the social consensus he advocates can be accomplished. He has no thorough discussion of the philosophy consensus, and of whether i t is achievable in our pluralistic society. But time will tell if the various grass roots experiments in democratic limit-setting that are now ongoing in many regions of the United States will be fruitful. Loewy appears to hope that a consensus is possible, based on a common wish to alleviate human suffering. He refers to the notion of “rationally controlled hostility” in considering the ways communities reach consensus with specific issues a t specific times. Allocation limits are real. We can add Loewy to a growing list of prominent physicians and philosophers looking to democratic processes for the establishment of priorities in health care that will make resources available on some acceptable level for all those in need. His attention to the actual medical condition of individuals is preferable to the more simplistic but less moral approach of categorically denying access to life-saving treatment simply on the basis of age.
Same-Sex Marriage: List of tables

List of tables Preface Same-sex marriage timeline 1. Marriage, culture and law 2. Doing the rite thing: cultural practices of commitment 3. How do I love thee? Questioning the marriage model 4. Making it legal: marriage, law and legality 5. Sin or civil right? Debating marriage in the states 6. Conclusion: marriage and beyond Epilogue Appendices Notes Court cases References Index.
PLASMA C-REACTIVE PROTEIN LEVELS AS A PROGNOSTIC MARKER IN FIRST EVER ACUTE ISCHEMIC STROKE

BACKGROUND AND PURPOSE: Acute ischemic stroke may trigger an inflammatory response that leads to increased levels of C-reactive protein (CRP). High levels of CRP may be associated with poor outcome because they reflect either an inflammatory reaction or tissue damage. We related plasma CRP levels to first ever ischemic stroke and its role as a diagnostic aid. METHODS: Sixty patients fulfilling inclusion and exclusion criteria with first ever acute ischemic stroke were included in study. CT scan of brain was done after 24 hours of onset of symptoms to confirm the diagnosis. Plasma CRP level was determined after 12 hours and before 72 hours of onset of symptoms in all CT confirmed ischemic stroke patients. This clinical study was done from January 2008 to June 2009. CRP was randomly measured in 60 age and sex matched individuals admitted in other wards of the hospital matched in all possible criteria expect the disease under study as a control group. RESULTS: The CRP concentration in ischemic strokes was independent of infarction site, the value was more between 51-70 years of age group and almost equal in both genders. 54 of the 60 ischemic strokes studied had CRP value >6 mg/l and only 6 patients had 6 mg/l, which is insignificant. CONCLUSION: The CRP level is significantly higher in ischemic strokes and by its elevation between 12-72 hours of symptom onset is a bad prognostic indicator. The risk of poor outcome or death at 3 months increased with higher levels of CRP. Elevated CRP values is a risk factor in association with other risk factors like diabetes/hypertension.
Effects of Zhuang Gu Guan Jie pills on Kidney Deficiency Osteoarthritis rat organ coefficient and total bilirubin

Objective To observe the impacts of Zhuanggu-guanjie Pill(ZGGJP) on organ coefficients and total bilirubin(TBIL) in normal rats,osteoarthritis rats and osteoarthritis rats with kidney deficient,and to evaluate the pill's pharmacological effect on osteoarthritis rats model with different syndrome.Methods: Oophorectomy method was used to build kidney deficient model,4 weeks later,anterior cruciate ligament and partial medial meniscus of right knee joint were cut to build osteoarthritis model.Drugs were oral administrated in low or high dosages after osteoarthritis operation,and lasted for 4 weeks.The body mass and organs mass were weight their organ coefficients,such as heart,liver,spleen,lung,kidneys,adrenal glands,and thymus gland and so on,were calculated and TBIL concentration in serum were tested also.Results: There was no rats died in the experimental period.Compared with normal control rats,organ coefficients of thymus gland,liver and adrenal glands in normal rats with high dosages of ZGGJP were significantly higher.Whereas in kidney deficient osteoarthritis rats,the thymus gland coefficient was obviously elevated,but the liver and kidney coefficients were significantly decreased.In addition,the TBIL contents in both normal rats and osteoarthritis rats were higher than that in normal control rats.Conclusion: The effects of ZGGJP oral administration in different types of syndromes were different,and were greater in normal rats,this clued the toxicity of ZGGJP was related with different syndrome types of diseases which were treated.These findings suggest that the drugs were applied according to syndrome differentiation so that a better clinical effect was obtained.
National Job Corps Study: Findings Using Administrative Earnings Records Data. Princeton, NJ: Mathematica Policy Research

This report uses annual Social Security earnings data employers report to the Internal Revenue Service, as well as quarterly wage records employers report to state unemployment insurance agencies, to examine impacts on earnings in years five to seven after random assignment. The research team found no impact on employment or earnings overall, suggesting that the benefits of the program are smaller than the substantial program costs. However, Job Corps may be cost-effective for older youth (those ages 20 to 24 when they applied to the program), whose positive earning gains observed early on in the evaluation persisted during the post-survey period. The authors note that only long-term followup can clarify questions about the program's cost-effectiveness.
The Relationship Between Memorable Messages and Identity Construction

Barros Campbell, Raphaela, M.A., Spring 2018 Communication Studies The Relationship Between Memorable Messages and Identity Construction Chairperson: Dr. Betsy Wackernagel Bach A qualitative analysis is reported here, in which 22 international students were interviewed about their overall experiences studying abroad, as well as memorable messages received and the context in which those were communicated. Scholars like Larson and Gill (2017) and Alvesson (2010) have focused on the role communication plays in constructing identity. With that in mind, Knapp et al.’s (1981) concept of memorable messages informs how specific messages influence individuals’ sense of who they are. This study expands knowledge on the relationship between memorable messages and international students’ identity construction, focusing on the impact of messages exchanged before and during their study abroad experience. MEMORABLE MESSAGES AND IDENTITY CONSTRUCTION iii
Enhancing Classroom Interaction Creatively

Creative language teaching that allows students to communicate freely enhances not only classroom interaction but also their interaction in the real world. Hence, this study examined the authentic classroom practices that encourage communication opportunities. Four classroom practices such as building prior knowledge, communitarian, multiple representations and protracted language events were observed, recorded and analyzed using weighted means, frequency counts, percentages, ranks and the Cochran Q-test. Findings revealed that building on prior knowledge and communitarian teachings were predominantly used followed by multiple representations and protracted language event, the least. The study showed that teachers use varied teaching practices to provide communication opportunities for students. The study recommends that: (1) the use of multiple representations and protracted language event should also be utilized by teachers to provide students with varied activities and to develop with confidence their communication skills; (2) Activities given to students should be more challenging to encourage them to ask questions that develop their critical thinking.
Human Activity Recognition Making Use of Long Short-Term Memory Techniques

The optimisation and validation of a classifiers performance when applied to real world problems is not always effectively shown. In much of the literature describing the application of artificial neural network architectures to Human Activity Recognition (HAR) problems, postural transitions are grouped together and treated as a singular class. This paper proposes, investigates and validates the development of an optimised artificial neural network based on Long-Short Term Memory techniques (LSTM), with repeated cross validation used to validate the performance of the classifier. The results of the optimised LSTM classifier are comparable or better to that of previous research making use of the same dataset, achieving 95% accuracy under repeated 10-fold cross validation using grouped postural transitions. The work in this paper also achieves 94% accuracy under repeated 10-fold cross validation whilst treating each common postural transition as a separate class (and thus providing more context to each activity).
Radiation safety awareness among patients and radiographers in three hospitals in Port Harcourt

People become nervous and worried whenever they are exposed to X-rays or similar forms of radiation. Such reactions may be attributed to ignorance, hearsay or actual knowledge of the harmful effects associated with these forms of radiation. To ascertain the true position a Radiation Safety Awareness survey was conducted among patients who receive X-ray irradiation at three Hospitals in Port Harcourt, Rivers State. The study employed the use of a carefully thought-out questionnaire administered to one hundred and fifty (150) patients and radiographers at the selected hospitals. Seventy-five of eighty (93.8%) of the radiographers, and sixty of seventy (85.7%) of patients responded. Of these 44 (58.7%) of the radiographers reported that they were aware of the dangers of ionizing radiation, while 52 (86.7%) of the patients expressed ignorance. We have shown that the patients’ awareness of the dangers of ionizing radiation is very poor while level awareness by the radiographers is unacceptable. In conclusion, concerted effort is to be made by all concerned for a successful healthcare delivery.
Assessment of the mental health of Irish Adolescents in the community

Aim: This study aims to assess a community of Irish adolescents using the Strengths and Difficulties Questionnaire (SDQ) for behavioural difficulties and mental health disorders. Method: All fifth and sixth class pupils attending eight primary schools were eligible to participate. The self-report version of the SDQ was administered to the pupils in the classroom. Results: Thirty participants (8.7%) had an abnormal SDQ score and 53 (15.3%) had a borderline abnormal SDQ score. Abnormal SDQ scores were more common among females (9.7%; mean score = 11.86; sd = 5.4) than among males (7.6%; mean score = 10.96; sd = 5.26). The difference was most pronounced on the emotional symptoms subscale (females received a mean score of 4.03 [sd = 2.1] compared to a mean male score of 2.90 [sd = 2.1]). Conclusions: Mental health problems are widespread among Irish adolescents. The SDQ is a useful preliminary assessment tool of the mental health profile of Irish adolescents and highlights the need for childhood mental health promotion in schools. The SDQ could also be used in a primary care setting to screen adolescents for mental disorders.
A Gadamerian hermeneutic study of nurses' experiences of recognising and managing patients with clinical deterioration and critical illness in a NHS trust in Wales

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Anti-Müllerian hormone predicts menopause: a long-term follow-up study in normoovulatory women

It has been postulated that the menopause is preceded by a fixed interval of natural sterility related to the number of follicles in the ovaries; the ovarian reserve. This paper hypothesized that an estimate of ovarian reserve might make prediction of age at menopause, which is highly variable, possible. This could then allow improved management of age-related infertility and timely initiation of preventive measures for menopause-related conditions associated with early or late onset of the menopause. This study proposed anti-Müllerian hormone (AMH), antral follicle count (AFC) and early-follicular folliclestimulating hormone (FSH) as candidate markers for estimation of ovarian reserve and prediction of age at menopause. The cohort comprised 302 normoovulatory women drawn from three previous studies. At time 1 (T1), an AFC was performed and AMH/early-follicular FSH concentration measured. At time 2 (T2), an average of 11.2 y post-T1, participants completed detailed questionnaires. On the basis of their answers, individuals were placed into five subgroups: regular cycle, menopausal transition, menopause, use of exogenous oestrogens or surgical removal of uterus/ovaries. Individuals in the latter two groups were excluded from the study, 45 could not be followed up and 12 had missing data, leaving 173 women available to be included in the statistical analysis. AMH, AFC and FSH at T1 were all significantly correlated with time to menopause (P , 0.001). With the exception of FSH, all markers had good predictive capacities, with that of AMH being further improved when adjusted for age (C-statistic, 0.9). A nomogram for prediction of age at menopause is presented in this paper and shows the normal distribution shifts considerably depending on age-specific AMH. Limitations of the study included the use of a cohort comprised of women from three previous studies. Furthermore, AMH concentrations in different groups were determined using different assays and a correction factor applied to align the results from the two assays. The numbers used for statistical analysis were fairly small, and larger studies would be required to confirm the findings of this paper. Most significantly, the spread of predicted age at menopause was large (an average of 5.8 y either side of the median), questioning whether AMH is an improvement on current predictors of age at menopause.