Miracle-dz/UniFAR-FTUs huggingface dataset:
Clinical Effect of Standardized Dietary Avoidance Therapy on Children with Milk Protein Allergy and Its Effect on Intestinal Flora

Objective The aim of this study is to analyze the clinical effect of standardized dietary avoidance therapy on children with cow milk protein allergy (CMPA) and its effect on the intestinal flora. Methods The clinical data of 200 children with CMPA from our hospital from February 2020 to May 2021 were collected, and they were divided into a study group (n = 100) and a routine group (n = 100) based on different intervention modalities. The routine group received routine treatment, whereas the standardized dietary avoidance therapy was used in the study group. The clinical effects and related intestinal microflora indexes of the two groups were analyzed and compared. Results There was no significant difference in the incidence of related symptoms between the two groups before intervention (P > 0.05), and the conditions of the two groups were improved after intervention. The incidences of skin (2%), digestive tract (3.00%), and respiratory tract (1.00%) in the study group were significantly lower than those in the routine group (14.00%, 18.00%, and 11.00%) (P > 0.05). The time taken for complete remission of symptoms and milk tolerance months in the study group (41.23 ± 23.68, 13.28 ± 6.17) were significantly shorter than those in the routine group (145.14 ± 66.74, 16.17 ± 8.05) (P > 0.05). The values of height, weight, and head circumference (HC) of children in the study group (79.88 ± 2.18, 11.09 ± 1.34, 47.88 ± 0.63) were higher than those in the routine group (76.21 ± 2.34, 9.81 ± 1.18, 45.98 ± 0.59) (P > 0.05). The levels of Lactobacillus and Enterococcus (9.95 ± 0.89, 11.31 ± 1.05) in the study group were higher than those in the routine group (9.11 ± 0.74, 10.38 ± 0.94), and the levels of yeast-like fungi in the study group (3.08 ± 0.24) were lower than those of the routine group (3.82 ± 0.31) (P > 0.05). Conclusion The standardized dietary avoidance therapy is remarkable in the treatment of CMPA, in which the children were able to tolerate ordinary milk earlier, and the intestinal flora was significantly improved, thereby promoting the growth and development of children. It therefore merits clinical promotion.
Role of Olaparib in the Management of Metastatic Castration-Resistant Prostate Cancer: A Japanese Clinician’s Perspective

Abstract Several studies have identified various targetable genomic alterations in prostate cancer, which accumulate during carcinogenesis and cancer progression. Genomic alterations in genes involved in DNA damage repair by homologous recombination repair may predict increased sensitivity to poly-ADP ribose polymerase (PARP) inhibitors. The Phase 3 PROfound trial has shown that treatment with the PARP inhibitor olaparib was associated with an improved radiographic progression-free survival and overall survival among patients with homologous recombination repair-deficient metastatic castration-resistant prostate cancer (mCRPC) after the treatment with androgen receptor targeting therapy, especially in men with BRCA1 or BRCA2 mutation. In Japan, olaparib was approved in December 2020 for the treatment of mCRPC with BRCA1 or BRCA2 mutation. In addition, genetic tests to detect BRCA1 or BRCA2 mutation to select patients who are likely to benefit from olaparib were also approved. This review summarizes the status of olaparib treatment for mCRPC, focusing on the situation in Japan.
Assessing the Effect of Underground Void on Strip Footing Sitting on a Reinforced Sand Slope with Numerical Modeling

This paper presents the results of the numerical analysis undertaken to investigate the effect of the underground void on the load-bearing capacity of a strip footing placed on an unreinforced and geogrid-reinforced sand slope with a void inside. The failure mechanism of the soil was also investigated. The numerical model was obtained using 2D plane-strain FEM analysis (in Plaxis software), in which the nonlinear Mohr-Coulomb model was utilized. The effects of various parameters such as the number of geogrid layers (N), the vertical distance ratio between the top of the cavity from the base of footing (H/B), the horizontal distance of void centerline to the footing center (X/B), on the behavior of footing are studied in this research. The results indicate that there is a critical zone under the footing in which the existence of void has no influence on the bearing capacity and stability of the footing. In addition, the use of geogrid reinforcement reduces the settlement and enhances bearing capacity. Finally, the bearing capacity factor and failure mechanism increase with increasing horizontal and vertical void distances ratios (X/B and H/B) and reinforcement layers.
Validation of the Short Food Literacy Questionnaire in the Representative Sample of Polish Internet Users

Analogous to health literacy, food literacy can be defined as a set of cognitive and social skills associated with the ability to acquire and understand information about food and nutrition to make appropriate nutritional decisions. In the literature, several terms such as food, nutrition, or nutritional literacy are used in parallel, differing in some aspects of their meaning. Food literacy is an important measure of the effectiveness of nutritional education interventions and appropriate instruments for its measurement should be available in every society. The aim of this study was the assessment of the validity and testing of a proposed model of the Short Food Literacy Questionnaire (SFLQ) culturally adapted into Polish. The analysis was performed on data from an online survey in a representative sample of 1286 adult internet users. Exploratory (EFA) and confirmatory factor (CFA) analyses were performed on two different subsets obtained through random splitting of the initial dataset. The Polish version of the SFLQ had good internal consistency (Cronbach’s α 0.841; Guttman split-half coefficient was 0.812). The EFA revealed that the tool had a three-factor latent structure. The distinguished dimensions were ‘information accessing’, ‘knowledge’, and ‘information appraisal’. The subscales also showed acceptable internal consistency based on the values of the Cronbach’s α coefficients (ranging from 0.768 to 0.845). The CFA confirmed a good fit of the three-factor model with at least five indexes achieving acceptable levels (CFI = 0.972, GFI = 0.963, AGFI = 0.940, NFI = 0.959, and RMSEA = 0.059). The validation of the Polish version of the SFLQ revealed, contrary to earlier reports, not a single but a three-factor structure of the instrument. The SFLQ will be an important tool for the assessment of the effectiveness of educational interventions and population studies analyzing the determinants of food literacy in Poland.
Insecticide spray regimes to manage Helicoverpa armigera (Hubner) and their impact on natural enemies in cotton under high density planting system

This study evaluated some new class insecticides viz., chlorantraniliprole 18.5SC, flubendiamide 480SC, spinosad 45%SC, indoxacarb 14.5SC and emamectin benzoate 5%SG in cotton under high density planting system (HDPS). These were evaluated against Helicoverpa armigera (Hubner) and their impact on natural enemies were also observed. Experiments were conducted at the ICAR-Central Institute for Cotton Research, Nagpur during 2013-14. Each of the new molecules were sprayed in eight different windows 60 days after sowing (DAS), 60 and 80 DAS, 60, 80 and 100 DAS, 60, 80 100 and120 DAS, 100 and 120 DAS, 80,100 and 120 DAS, 120 DAS and unsprayed control along with three replicates each were analysed in randomized complete block design. The damage by H. armigera was observed by counting healthy and damaged squares and bolls, and % worked out. The whole plant incidence was recorded in case of major predators sampled including spiders and coccinellids. The spray regime 2 (60 and 80 DAS), regime 3 (60, 80 and 100 DAS), regime 4 (60, 80, 100 and 120 DAS) and regime 6 (80, 100 and 120 DAS) were found superior in managing bollworms with by recording least square damage. The results on natural enemies’ populations (spiders and coccinellids) clearly revealed that, all spray regimes were more or less safe to the natural enemies. However, spray regime 1 (spray at 60 DAS), regime 2 (spray at 60 and 80 DAS) and regime 3 (spray at 60, 80 and 100 DAS) recorded maximum natural enemies. Maximum natural enemies was reported at 80 DAS in all the insecticidal spray regimes. Chlorantraniliprole, flubendiamide, spinosad, indoxacarb and emamectin benzoate through the spray regime 2 (spray at 60 and 80 DAS) was observed to be the best option against H. armigera by controlling it in early stage itself and to sustain natural enemies in the cotton ecosystem.
Population Dynamics of Major Insect Pests of Common Bean in Kashmir Valley

This study is on the bean aphid Aphis fabae Scopoli, whitefly Bemisia tabaci (Genn.), bean weevil Conapium sp. indet. , flea beetle Altica himensis Shukla which are found associated as pests at different phenological stages of the common bean Phaseolus vulgaris L. Of these A. fabae, B. tabaci and Conapium sp. indet. were categorized as major pests as they caused significant damage. The incidence of these pests showed a peak on the 35th standard meteorological week (SMW) in all the three locations studied. The peak incidence at Bandipora was 11.80 ± 0.66, 3.10 ± 0.58 and 1.20 ± 0.08, respectively; at Baramulla, the peak was 10.40 ± 0.62, 3.40 ± 0.13 and 1.30 ± 0.07, respectively; and at Kupwara, it was varying as 12.60 ± 0.69, 3.40 ± 0.13 and 1.30 ± 0.07 for the three pests, respectively.
Mobilities and home: the notion of becoming insiders among the Sri Lankan Northern Tamil IDPs in Colombo

Abstract This article considers the varied complexities of forced migration, belonging, virtual and imagined mobilities, and ideas of home. Addressing the idea of home among the internally displaced persons (IDPs) of Sri Lanka, this article will seek to explain how they locate home and their approaches towards returning. Doing so will elucidate the extent of IDP’s feelings of ‘insider’ or ‘outsider’ status at their places of displacement. The collected data will be analyzed through theoretical frameworks that consider differing notions of home, mobility and sense of belonging. Drawing on the life experiences of the Tamil IDPs in the capital city of Colombo in Sri Lanka, I will argue that home has become mobile for many of the respondents. Through assimilation, many IDPs have successfully adapted to their new locales, viewing it more suitable than their places of origin. The collective research is qualitative in nature, analyzed through the use of primary and secondary data collected in Colombo in three phases, from January to March 2013, November to December 2019 and September to December 2021. Findings suggest that displacement has facilitated the process of recreating experiences of home in Colombo. I argue that IDPs are able to carry their homes along with them in ways that transcend the limitations of time or space. However, they are still on the journey of ‘becoming insiders’, not yet ‘being insiders’.
Aphrodisiac Effect of Aloe vera Gel Supplementation in Diet of Drosophila melanogaster Meigen

The well-established model organism Drosophila melanogaster Meigen was used in the present study to ascertain the aphrodisiac property of Aloe vera gel supplementation in diet on it’s mating behaviour and fitness parameters. The results revealed that the gel supplementation enhanced its reproductive performance. Male Drosophila individuals with high vigour (short mating latency period) reacted quickly in a female’s presence, while a male with less vigour (a large mating latency period) responded slowly. Copulation duration was found to be negatively correlated with mating latency. Treated groups showed longer copulation duration and shorter mating latency period. Female fecundity was observed to be significantly and positively correlated with copulation duration. Increased copulation duration in A. vera supplement fed females revealed increased egg lying. Thus, A. vera gel supplemented diet enhances the reproductive fitness parameters in D. melanogaster.
Farmer Led Irrigation Initiatives And Its Impact On The Livelihoods Of Smallholder Farmers Under Redistributed Lands: A Case Study Of Mazowe District A1 Resettled Farmers, Zimbabwe

: Farmer led irrigation farming (FLI) is a vital strategy in the livelihoods of smallholder farmers especially the A1 model resettled farmers in Zimbabwe who now operate in an unpredictable natural and economic environment which has become more and more volatile especially under the prevailing climate changing environment and more recently global epidemics like COVID 19. FLI is now a revolutionary agricultural intensification approach which is already in progress and has the magnitude to significantly transform the living standards of smallholder farmers. However a rigorous assessment of its impact of A1 resettled under its Fast Track Land Reform (FTLRP) is lacking. This study bridges the gap by assessing role of FLI farming iniatives on the livelihoods of resettled farmers under redistributed lands in Mazowe District in Mashonaland Central Province in Zimbabwe. The sample size for the study for quantitative data was 310 A1 farmers practicing FLI in Mazowe District while 5 public officers were for qualitative data. A questionnaire was used to collect household data. Processing of data was done using the Structural Equation Model (STEM). This study found out that smallholder farmer led irrigation had a positive impact on the socio economic aspects of the livelihoods of A1 resettled farmers under Mazowe District of Mashonaland Central Province of Zimbabwe. The study, therefore, recommended ICT development for extension officers who in turn are expected to assist A1 farmers as they embark on FLI farming while improving level of education will help farmers acquire the necessary information needed for decision making under the FLI. Government subsidy interventions will help farmers acquire FLI hardware at affordable costs while enhanced female participation is also envisaged to help stabilize household food security situations. The study also recommends further studies to establish other factors that might provide further insights into the effect of farmer led irrigation farming on livelihoods of farmers.
Theoretical study of P1 wave passing through a double-layer wave impeding block in the unsaturated soil

Based on the propagation theory of elastic waves in unsaturated porous medium and single-phase elastic medium, the calculation model of a double-layer wave impeding block (WIB) as vibration isolation barrier in unsaturated soil foundation is established. The analytical solution of the transmission/reflection amplitude ratio of P1 wave passing through a double-layer WIB in unsaturated soil foundation are derived by Helmholtz vector decomposition theorem. The influences of physical and mechanical parameters such as saturation, wave impedance ratio, density, and shear modulus on the vibration isolation effect of the double-layer WIB when P1 wave passing through the double-layer WIB in the unsaturated soil foundation are analyzed by parametric studies. The results show that the saturation has a small effect on the transmission/reflection coefficients of P1 and S waves and a significant effect on the transmission/reflection coefficients of P2 and P3 waves. The wave impedance ratio and the shear modulus and density of the double-layer WIB have a significant effect on the transmission/reflection coefficients. The optimal shear modulus and wave impedance ratio of the double-layer WIB can be selected to obtain the best vibration isolation effect, which provides theoretical guidance for the application of the double-layer WIB in the field of unsaturated ground vibration control.
Thermal Properties of Solar Collector Comprising Oscillating Heat Pipe in a Flat-Plate Structure and Water Heating System in Low-Temperature Conditions

Solar collectors are very important to the photothermal utilization of solar energy in low-temperature conditions. In this paper, a solar collector comprising an oscillating heat pipe in a flat-plate structure is designed and studied experimentally. The thermal properties are studied in detail, and we finally obtain the startup temperature and the expression of the instantaneous efficiency with a relative error of 5%. The results show that the impact of inclination angles on the startup properties of the solar collector is significant to the thermal properties. The comparisons of the efficiency of the present design and similar products are also displayed and discussed, showing that an oscillating heat pipe collector in a flat-plate structure overcomes the low efficiency, high startup temperature and bad pressure resistance of conventional solar collectors. In addition, the thermal properties of the water heating system based on the novel collector were also tested, illustrating the differences between the solar irradiance and the water heating system. Some improvements (e.g., shell material and assembly method) were made in this system design process to increase the heat transfer efficiency and solve the corrosion and pressure resistance problems.
The Association of Gender and Mortality in Geriatric Trauma Patients

The association of gender with mortality in trauma remains a subject of debate. Geriatric trauma patients have a higher risk of mortality compared to younger patients. We sought to evaluate the association of gender with mortality in a group of geriatric trauma patients presenting to an academic level 1 trauma center (trauma center designated by New York State capable of handling the most severe injuries and most complex cases). Methods: We performed a retrospective review of geriatric trauma patients who were admitted to our trauma center between January 2018 and December 2020. Data collected included vital signs, demographics, injury, and clinical characteristics, laboratory data and outcome measures. The study controlled for co-morbidities, injury severity score (ISS), and systolic blood pressure (SBP) in the ED. Multivariable logistic regression analysis was performed to evaluate the association of gender and mortality. Results: 4432 geriatric patients were admitted during the study period, there were 1635 (36.9%) men and 3859 (87.2%) were White with an average age of 81 ± 8.5 years. The mean ISS was 6.7 ± 5.4 and average length of stay was 6 ± 6.3 days. There were 165 deaths. Male gender (OR 1.94, 95% CI 1.38 to 2.73), ISS (OR 1.12, 95% CI 1.09 to 1.14), Emergency Department SBP less than 90 mmHg (OR 6.17, 95% CI 3.17 to 12.01), and having more than one co-morbidity (OR 2.28, 95% CI 1.55 to 3.35) were independently predictive of death on multivariable logistic regression analysis. Conclusion: Male gender, Emergency Department systolic blood pressure less than 90 mmHg, having more than one co-morbidity, and injury severity are independent predictors of mortality among geriatric trauma patients.
Design, implementation and evaluation of a postgraduate workshop on cross-border healthcare in Europe – Mixed methods research

Introduction In European border regions, healthcare providers join forces to make full use of the potential of healthcare. Trainees need to be aware of the challenges and opportunities of cross-border healthcare. To increase such awareness, a workshop was designed, implemented and evaluated. The workshop was entitled ‘Creating cross-border collaborators’ and combined elements of contextual, collaborative and reflective learning. The aim of the study was to understand how this workshop enhanced trainees’ awareness of challenges and opportunities of cross-border healthcare. Methods Using a mixed-methods approach, focus-group interviews (QUAL) were held with trainees (N = 16) and trainees (N = 13) completed a survey (QUAN) about their workshop experiences. The workshop was held three times for three different groups of trainees. Results Quantitative analysis (of surveys) demonstrated increased self-reported awareness of cross-border healthcare. All learning principles contributed to this awareness, however reflective learning slightly less. Qualitative analysis (of focus-group interviews) unearthed the following four themes: (1) Attention to cross-border healthcare fostered awareness of its complexity; (2) real-life examples stimulated recognition of challenges and opportunities; (3) discussions in interdisciplinary and international groups helped to see different perspectives; and (4) reflection made trainees think about their own role and perspective. Quantitative and qualitative data are strongly cohered. Conclusion According to participating trainees, a workshop with elements of contextual, collaborative and reflective learning did improve trainee awareness of cross-border healthcare. This study highlights that theoretical insights into learning can and should inform the design and evaluation of workshops.
Sustainability Performance and the Cost of Capital

This study examines the association between firms’ environmental, social, and governance (ESG) performance and the cost of capital for the largest European firms listed on the STOXX Euro 600 in a large panel from 2002 to 2018. We find that ESG is priced by both debt and equity markets, although in different directions. While better ESG performance is associated with a lower cost of equity, the relationship is positive regarding the cost of debt. We also account for industry idiosyncrasies. The relationship with the cost of equity is penalized for firms lagging in ESG performance compared with industry peers, and the industry median corporate sustainability performance score is around optimal to balance the cost of equity and cost of debt. We also find that ESG is not influential in shaping firms’ cost of capital in periods of financial and sovereign crises. Overall, in the same research setting, we find that the channels of firms’ cost of capital composition behave differently in response to changes in sustainability performance.
English For Chemistry Book As A Learning Resource In University

This study is a specified inspection of the development of the chemistry educational sources. The purposes of this study are: (1) to develop a book “English for Chemistry”, (2) to assess the quality of the book based on appraisement of lecturers and students. The type of the research is R & D. There many stages carried out in this investigation developed by Borg & Gall. The instrument used to assess the quality of this book is a set of quality having some aspects and criteria. The evaluations included 6 aspects with 33 criteria for lecturers and 4 aspects with 25 criteria for students. The evaluation result is in qualitative data and then the result is analyzed by the ideal evaluation criteria category guide to determine the quality of the book. Based on lecturers’ assessments, the book has a good quality, going to the score of 116 out of 165 and ideal percentage 70.3%. Meanwhile, in students’ side, the book is also classified as a good quality, whose score is 103 out of 125 and ideal percentage 82.4%. Development english for chemistry book, helping student understand scientific words of chemistry in english.