Miracle-dz/UniFAR-FTUs huggingface dataset:
Male Factors: An Ignored Etiology in Recurrent Pregnancy Loss

The etiologies of recurrent pregnancy loses could be chromosomal aberrations, uterine defects, immunological problems, endocrinological problems, advanced reproductive age, sperm deformities and gene mutations. But most often the male factors are neglected and not consider as major factor in Pregnancy loss. In male partner of the patients with recurrent pregnancy loss RPL have a significant increase in sperm DNA fragmentation and decreased sperm functions. This study was conducted to evaluate the correlation between male factors and pregnancy loss. In our study with 50 idiopathic RPL cases 30 cases were identified with female factors responsible for RPL, 7 cases with both male and female eitiologiesand rest 13 were idiopathic. Randomly selected males were taken as controls with proven fertility rate and compared with RPL group. The semen samples of the respective male partners were analysed along with basic semen analysis procedures. Sperm function test was carried out by Hypo-osmotic swelling test (HOS), Acrosomal Reaction (AR) and Nuclear decondensation test (NCD). Sperm motility, viability and sperm function tests scores were significantly lower in the RPL group when compared to the control group. Through this pilot study it is significant that male factor might be a possible contributing factor towards RPL. Therefore both the partners should be evaluated and treated simultaneously in order to achieve successful pregnancy
The connectivity of the Paranapanema River with two lateral lakes in its mouth zone into the Jurumirim Reservoir

: The connectivity of the Paranapanema River with two lateral lakes in its mouth zone into the Jurumirim Reservoir. The pattern of hydrological interactions of the Paranapanema River with two lateral lakes in its mouth zone into the Jurumirim Reservoir was examined during a four-year period (from January 1, 1998 to December 31, 2001). Measurements of water level and precipitation were obtained. The volume and surface area variability of the two lateral lakes was described for the study period. Except during a prolonged period of drought (from October 1999 to December 2000), the lakes were connected with the Paranapanema River, and the annual range of water level was around 2.4-3.0m. The variability of the lateral hydrologic pulse produced highest variation in surface area than volume in the two lakes (except during the drought period). However, the area elasticity coefficient of one of the lakes (Camargo Lake) was around 50% smaller than the other (Coqueiral Lake). The volume elasticity coefficient of the Camargo Lake was around five times smaller than of the Coqueiral Lake. The differences on elasticity coefficients were attributed to the morphometry of the lakes. Except during the drought, the lateral environments are maintained permanently in a potamophase. This type of behavior is not a characteristic of a floodplain. Thus, the stored water in the Jurumirim Reservoir acts as a buffer system of hydrological pulses, in the riverine zone of reservoir.
Prognostic Value of Lymph Node Ratio in Breast Cancer Patients with Adequate Pathologic Evidence After Neoadjuvant Chemotherapy

Background The prognostic role of axillary lymph node ratio (LNR) after neoadjuvant chemotherapy (NAC) in breast cancer has not been illuminated. This study was designed to investigate the prognostic role of LNR in breast cancer compared with traditional ypN stage. Material/Methods A total of 306 breast cancer patients diagnosed with positive axillary lymph nodes from January 2007 to December 2014 were eligible for this retrospective analysis. All enrolled patients were treated with a median of 4 cycles of NAC followed by mastectomy and level I, II, and III axillary lymph node dissection (ALND). Results The median duration of follow-up was 78 months (range, 7–147 months). Univariate analysis indicated that both the LNR category (P<0.001) and ypN stage (P<0.001) were significant associated with event-free survival (EFS) and overall survival (OS). However, multivariate analysis indicated that the LNR category was independently associated with EFS (P<0.001) and OS (P<0.001), while the ypN stage showed no statistical effect on EFS (P=0.391) or OS (P=0.081). On additional analyses stratified by molecular subtypes, we found that the prognosis of triple negative breast cancer could be better discriminated when the cutoff value of LNR was set at 0.15. Conclusions LNR showed a superior predictive value in evaluating prognosis of breast cancer patients after NAC. In addition, the LNR cutoff point 0.15 can accurately discriminate survival outcomes for different triple negative breast cancer subtypes.
BIOINFORMATICS TOOL DEVELOPMENT AND SEQUENCE ANALYSIS OF ROSACEAE FAMILY EXPRESSED SEQUENCE TAGS

BACKGROUND: An international community of researchers has generated a significant number of Expressed Sequence Tags (ESTs) for the Rosaceae, an economically important plant family that includes most temperate fruits such as apple, cherry, peach, and strawberry as well as other commercially valuable members. ESTs are fragments of expressed genes that can be used for gene discovery, developing markers for mapping and cultivar improvement via marker assisted selection. DESCRIPTION: The Genome Database for Rosaceae (GDR) was initiated to provide a curated and integrated web-based relational database for this family. I developed a key component of GDR to assemble and annotate the publicly available ESTs from the four main genera of the family (Prunus, Malus, Fragaria, Rosa). I created both genera and family level unigenes using the software CAP3 after extensive filtering, trimming and assembly. Further analysis includes marker mining for single nucleotide polymorphisms (SNPs) and simple sequence repeast (SSRs) with putative primer identification, and oligo identification for potential microarray development. Functional genomics efforts are supported with sequence similarity searching against major protein and nucleotide databases, gene product ontology assignment, and protein motif identification. I deployed the entire project on the GDR with all data available for browsing, searching, and downloading.
Hemophagocytic Lymphohistiocytosis in Children : Queen Rania Children's Hospital Experience

Results: Total number of cases were 42; 23 males (54.8%) and 19 females (45.2%), age was ranged from one month to 12 years. All patients met five to six criteria out of the eight HLH-2004 criteria: all patients had fever, splenomegaly, cytopenias and hemophagocytosis in the bone marrow examination; hyperferritinemia at time of presentation was seen in (95.9%), and proven CNS involvement in 10 patients (23.8%). A significant number of our cohort had oculocutaneous albinism phenotype (18 patients; 42.9%). Primary HLH was considered in 69%, while secondary or reactive HLH in 31%. All patients had received corticosteroids and cyclosporine as initial therapy, etoposide (VP-16) had been used only in 6 patients, rabbit antithymocyte globuline (ATG) in 5, and 10 patients (23.8%) received 11 allogenic hematopoietic stem cell transplantations (HSCT) as a curative treatment. The overall survival rate was 81%, HSCT group showed excellent outcome with survival rate of 90%.
Distorted Technology Adoption

I study institutional distortions as a driver of cross-country technology differences. I develop a quantitative model of heterogeneous firms that differ in underlying productivity and their institutional environment. Institutions that distort more productive firms delay the adoption of new technologies by decreasing investment of (otherwise) early adopters. Quantitatively, distortions explain around half of the observed crosscountry variation in adoption lags. Additionally, technology increases the loss from misallocation by double compared to a setting in which technology is held fixed.
The Value of Persian Weaning Tool in Prediction of Patients’ Weaning Outcome Compared with Physician- Directed Approach: A Diagnostic Accuracy Study

Background: One of the important criteria in patients receiving artificial respiration is the time of weaning from the mechanical ventilator. As physician’s decision might be somehow subjective, several tools have been suggested for prediction of the time of weaning more objectively. This study aimed to determine the predictive value of Persian Weaning Tool (PWT) compared with Physiciandirected approach as the gold standard. Methods: This diagnostic accuracy study was done in 2016-2017 in Two Medical and Educational Centers of Gorgan, Iran. 97 admitted patients in intensive care units, under mechanical ventilation were evaluated. The patients were recruited into the study by a convenience sampling method and evaluated for readiness to wean using two approaches (physician’s decision and using PWT). Successful weaning was considered as the ability of patient to breathe spontaneously during the first 48 hours after weaning. The sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), positive likelihood ratio (PLR), and negative likelihood ratio (NLR), as well as the agreement (kappa coefficient) between the two approaches, were calculated. In addition, to compare the differences between variables in two groups, chi-Square, T and man-Whitney tests were used. All analyses were performed using SPSS software ver.16, and MedCalc program ver.13. P<0.05 was considered as statistically significant. Results: Most patients (64.9%) were men. The mean age, duration of hospital admission, and D ow nl oa de d fr om g ou m s. ac . ir a t 7 :2 5 + 04 30 o n S at ur da y A pr il 25 th 2 02 0
Management Of Urd Bean Leaf Crinkle Virus In Urd Bean (Vigna Mungo L. Hepper)

Six plant extracts viz , Mirabtlis jalapa, Carthamus roseus. Datura metal, Bougainvitlea spectabilis, Boerhaavia diffusa and Azadirachta indica recorded maximum reduction in the incidence of urd bean leaf crinkle virus (ULCV) in urd bean crops at field level Among the antiphytovirat chemicals tested, DHT reduced the transmission to the maximum extent and increased the incubation period of virus in the urd bean plant Fresh buttermilk was significantly superior to fermented buttermilk in reducing the disease spread and increasing the incubation period of the virus in the plant. Casein was found effective in reducing the per cent transmission and increased the incubation period of the virus. Raising barrier crops viz maize, sorghum and pearl millet were equally effective in reducing the spread of the disease in field Spraying of DHT at two intervals. 7 and 22 DAS was found effective in reducing the disease spread when compared with Thuja, buttermilk, ivf jalapa and neem oil.
Effect of crop density on yield of bean Pinto Saltillo under irrigation in Chihuahua, Mexico

Resumen Se describen estudios sobre el uso de las altas densidades en frijol de riego en el estado de Chihuahua. La mayoria de los productores de frijol de riego cosechan una densidad por debajo de las recomendaciones de INIFAP. Los objetivos de los estudios aqui reportados fueron: a) realizar un muestreo aleatorio en parcelas comerciales de productores de frijol de riego en Chihuahua para determinar la poblacion de plantas en uso; y b) evaluar el rendimiento de grano de la variedad Pinto Saltillo de riego con diferentes densidades, localidades y anos. El muestreo de densidad en parcelas de productores de frijol de riego se realizo en 2009. Los experimentos para determinar el uso de altas densidades o densidades optimas se realizaron en 2010 en Fco. I. Madero, Bachiniva y en 2011 en Carbajal de Abajo, Cusihuiriachi e Independencia, Namiquipa. En cada localidad se utilizo el sistema de riego disponible por el productor pivote central, en las dos primeras localidades y sistema de aspersion manual en la tercera localidad. La fertilizacion y el manejo vario de acuerdo al productor. Las densidades utilizadas variaron desde 1 hasta 16 plantas por metro lineal (planta por m
Structure génétique et évolution de la spécialisation chez deux ectoparasites hématophages, les tiques Ixodes uriae et I. Ricinus, vecteurs de la borréliose de Lyme

De nombreuses etudes ont ete consacrees a expliquer la diversite du vivant. Chez les parasites, la specialisation pour differents types d'hotes peut etre un processus cle dans l'emergence et le maintien de cette diversite. Les traits d'histoire de vie du parasite et de ses hotes conditionnent la structuration de la variation genetique dans le temps et l'espace, et de la, la possibilite des divergences liees a l'hote. Dans cette these, nous nous sommes interesses a l'evolution de la specialisation dans deux systemes hotes/parasites impliquant des vecteurs de la borreliose de Lyme: les tiques Ixodes uriae, qui exploite les oiseaux marins coloniaux des regions polaires, et Ixodes ricinus, que l'on rencontre sur un large spectre d'hotes terrestres en Europe. Ces deux congeneriques ont en commun de nombreux traits, mais different notablement dans les types d'hotes qu'ils exploitent et leur strategie de rencontre. D'apres les elements de la biologie de base de ces especes, nous avons formule plusieurs hypotheses sur la repartition de l'information genetique de ces parasites en populations naturelles, et plus particulierement entre leurs hotes a l'echelle locale. De larges echantillonnages ont ete realises, et les tiques ont ete caracterisees a l'aide marqueurs microsatellites et mitochondriaux. Ces donnees ont ete analysees a l'aide de differents outils statistiques frequemment utilises en phylogeographie et en genetique des populations, incluant des methodes recemment developpees. Dans leur ensemble, les resultats ont permis d'etablir un scenario d'evolution recente et recurrente de la specialisation chez I. Uriae, qui varie en fonction des traits des hotes et leurs interaction locale avec la tique. Nos resultats suggerent egalement l'existence chez I. Ricinus de races specialisees sur differents types d'hotes (oiseaux, petit mammiferes, etc. ), et de mecanisme d'appariement assorti des partenaires sexuels au sein de ces races. Cette etude souligne l'importance des traits des parasites dans leur diversification (dispersion, strategie de rencontre des hotes et d'appariement). En particulier, la formation des races d'hotes dans les populations de tiques va fortement affecter la circulation des pathogenes qu'ils transportent, et remet ainsi en cause nos connaissances actuelles sur l'epidemiologie des maladies a tiques comme la borreliose de Lyme
A Qualitative Study on Acehnese Exposed to Traumatic Experience: Post Tsunami

The present study is a documentary based on a true civil war that had transpired between the Indonesian government and Free Aceh Movement (GAM). The insurgency in Aceh was a conflict fought by the Free Aceh Movement (GAM) between 1976 and 2005, with the goal of making the province of Aceh independent from Indonesia. In 2004, Aceh had been struck by the worst Tsunami in history which affected and changed 360 degrees the lives of Acehnese. The building of Aceh Baharu, highlights the Acehnese struggle and development for the betterment of Aceh. Therefore, the present study is aimed to draw factors influence towards traumatic experience amongst the Acehnese. The three factors draws based on the first observations are human violations, Aceh Current Development and Community Social Cohesion. This is a qualitative study which applies a cross-sectional observation and one-to-one in-depth interview. In addition, researchers will be actively present on the field of observation to witness the post tsunami development on exposed traumatic experience among the Acehnese. Apart of finding factors influence on traumatic experience. All recorded in-depth interview as well as observation process will be presented in a documentary form to demonstrate Aceh today with Acehnese new life’s without human violations current development of its infrastructure, economics, culture and continuous community social support which later renamed as ‘Aceh Baharu’. Therefore, the present study hopes to initiate the new beginning of Aceh investors and outsiders to invest and visit Aceh. It will also impact on the tourism sector to improve Acehnese lives.
Food quality affects diet preference of rabbits: experimental evidence

When foraging, small mammalian herbivores do not show a preference for the forage with the highest biomass, which can be explained by several hypotheses (e.g. antipredator considerations, more difficult handling of tall swards and/or the higher nutritional quality of shorter grasses). We tested the ability of rabbits to discriminate between plants of different nutritional value and whether they prefer the most nutritious. A feeding trial in which rabbits (Oryctolagus cuniculus (Linnaeus, 1758)) were offered two different types of grasses (fertilised and unfertilised) was executed under experimental conditions. The rabbits pre- ferred the grasses with the highest protein percentage, when conditions were controlled for sward height/plant biomass. This obser- vation is equivalent to results obtained in geese and provides experimental evidence about the capability of rabbits to select for plants with the highest nutritional quality.
A study on comparison of short term three dose antibiotic prophylaxis with conventional prolonged postoperative antibiotic coverage in development of surgical site infections

Surgical site infections are still an increasing threat to the surgeons despite advances in techniques of surgery, patient care and sterilization practices. They are the most common health care associated infections as reported globally. They are associated with prolonged hospital stay, increased economic loss, additional surgical procedures and increase chances of mortality. Multiple risk factors are involved in development of SSI ranging ABSTRACT
{null=Description of Rhyssocolpus vinciguerrae sp. n. (Dorylaimida, Nordiidae) from Iran and the first molecular study of this genus, en=Description of Rhyssocolpus vinciguerrae sp. n. (Dorylaimida, Nordiidae) from Iran and the first molecular study of this genus}

{null=Rhyssocolpus vinciguerrae sp. n. , from natural habitats in Iran, is described, illustrated and sequenced. It is characterised by the body length of 1.04-1.37 mm, lip region offset by depression and 11-13 μm broad, odontostyle 8-10 μm or 0.7-0.8 times the lip region diam. long, neck 227-265 μm long, pharyngeal expansion 80-95 μm long or 31-35% of total neck length, a dorsal cell mass present between cardia and the end of the anterior ovary/testis, uterus bipartite, 90-170 μm long, vulva longitudinal (V = 48-55), abundant irregularities in body cuticle around vulva, female tail conical with rounded terminus (35-55 μm, c = 24-34, c′ = 1.4-1.9), spicules 43-51 μm long and 6-8 spaced ventromedian supplements located outside the range of the spicules. It is very similar to R. aquilonius, R. arcticus and R. iuventutis. A molecular characterisation of the new species was done on ribosomal DNA nearfull-length small subunit 18S gene, internal transcribed spacer and partial 5.8S gene. The results obtained support a close relationship between Rhyssocolpus and Heterodorus, and a more distant relationship with Enchodelus. , en= Rhyssocolpus vinciguerrae sp. n. , from natural habitats in Iran, is described, illustrated and sequenced. It is characterised by the body length of 1.04-1.37 mm, lip region offset by depression and 11-13 μm broad, odontostyle 8-10 μm or 0.7-0.8 times the lip region diam. long, neck 227-265 μm long, pharyngeal expansion 80-95 μm long or 31-35% of total neck length, a dorsal cell mass present between cardia and the end of the anterior ovary/testis, uterus bipartite, 90-170 μm long, vulva longitudinal (V=48-55), abundant irregularities in body cuticle around vulva, female tail conical with rounded terminus (35-55 μm, c=24-34, c′=1.4-1.9), spicules 43-51 μm long and 6-8 spaced ventromedian supplements located outside the range of the spicules. It is very similar to R. aquilonius, R. arcticus and R. iuventutis. A molecular characterisation of the new species was done on ribosomal DNA near-full-length small subunit 18S gene, internal transcribed spacer and partial 5.8S gene. The results obtained support a close relationship between Rhyssocolpus and Heterodorus, and a more distant relationship with Enchodelus. }
The Practice of Interventional Gastrointestinal Endoscopy at a Tertiary Referral Hospital

Background : Interventional endoscopy enables one time diagnosis and treatment of gastrointestinal diseases with minimally invasive therapy and improved disease outcome. Local use has remained low with minimal reporting. Knowledge of current practice at a tertiary level may promote utilization of interventional gastrointestinal endoscopy. Objective : To describe the practice of interventional gastro intestinal endoscopy at Kenyatta National Hospital. Methods : In a prospective descriptive study consecutive sampling was used. Main variables were interventional procedure offered, sedation mode and immediate outcome of the procedure. Results : There were 211 cases and interventional endoscopy accounted for 21.7% of these.The male: female ratio was 1:0.9. The median age group was 41-50 years. Variceal band ligation, ERCP and esophageal stenting were the three most common procedures. No mortalities were recorded during the period of study. Conclusion : Our report describes application of interventional endoscopy in a variety of gastrointestinal diseases with acceptable immediate outcome. Key words : Interventional, Endoscopy, Varices, Banding
New Goals for Biology Education: Helping Teachers Make Science Accessible to More Students.

tion reform efforts is rapidly moving across the country. Among the reforms are Scope, Sequence, and Coordination (National Science Teachers Association); Project 2061 (American Association for the Advancement of Science); State-Wide Systemic Initiatives (National Science Foundation); and national goals and standards (National Research Council). Each reform attempts to define goals and develop materials and strategies for achievement. There is not just concern about the quality of education; there is also financial backing and considerable effort going toward changes. And, many of these efforts are aimed at changing not just one small aspect but the overall system of the educational enterprise-the curriculum, the role of teachers and teacher education, students, administrators, and evaluation. I currently codirect BioCom, one example of reform. BioComl is a tenth-grade curriculum that covers only eight topical units for a whole year. It focuses on a few basic ideas in each unit, requires less mathematics than other biology courses, and downplays the memorization of vocabulary words. Three units of BioCom-biodiversity, the biosphere, and ecosystems-are related to the environment. In addition, every unit has aspects of ecology,
SOLID WASTE AND EMERGENCY RESPONSE

VE is a highly beneficial technique used to reduce nonessential procurement and program costs. VE uses systematic and creative methods to reduce costs without sacrificing the reliability, efficiency, or original objectives of the project. Implementation of VE techniques by Federal Departments and Agencies was first required by the Ofice of Management and Budget Circular No. A-13 1, Januahy 26, 1988. Circular A-1 3 1 was last revised in 1993. The policies of Circular A-13 1 have been incorporated into the Federal Acquisition Regulation (FAR).