Miracle-dz/UniFAR-FTUs huggingface dataset:
Administration of Intravenous Lipid Emulsion for Dextromethorphan Poisoning with Serotonin Syndrome: A Case Report

Dextromethorphan (DXM) is used to treat colds and coughs; however, it can cause central nervous system symptoms, such as severe serotonin syndrome (SS). To our knowledge, there is no specific treatment for severe DXM poisoning, and there are no reports on the clinical use of intravenous lipid emulsion (ILE) for its treatment. Herein, we report a case of severe DXM poisoning with SS that was successfully treated with ILE. An older adolescent male visited the emergency department 1 h after ingesting 4500 mg of DXM orally. Physical examination revealed generalized convulsions, muscle rigidity, mydriasis (8.0/8.0 mm), and flushed skin, with a Glasgow Coma Scale score of 8 (E3V1M4). Severe DXM poisoning with SS was diagnosed. The patient was intubated and administered midazolam for continuous convulsions and SS. Activated charcoal was also administered, and body surface cooling was performed. After an 11 h intensive care unit admission, SS with mydriasis (6.0/6.0 mm) did not improve. Subsequently, 1100 mL of 20% soybean oil was injected as an ILE. Mydriasis improved (3.5/3.5 mm) 30 min after ILE administration; simultaneously, blood DXM concentration rapidly increased approximately two-fold. After discontinuing midazolam, the patient’s consciousness signs improved, and he was weaned off the ventilator. SS was cured with no recurrence of convulsions. In cases of DXM poisoning with severe central nervous system disorders, such as SS, ILE treatment can potentially be an effective therapeutic option. For oral overdose cases, where the drug may remain in the intestinal tract, measures such as administering activated charcoal should be taken before administering ILE.
Use of Advanced Hybrid Closed-Loop System during Pregnancy: Strengths and Limitations of Achieving a Tight Glycemic Control

Background: Pregnant women with type 1 diabetes mellitus (T1DM) face an elevated risk of complications for both themselves and their newborns. Experts recommend strict glycemic control. The advanced hybrid closed-loop (AHCL) system, though not officially approved for pregnant T1DM patients, is promising for optimal glycemic control. Methods: We collected CGM metrics, HbA1c levels, insulin pump settings, and doses from a 33-year-old pregnant woman with 23-year history of T1DM from the 6th week of gestation to birth. She was initially on continuous insulin pump therapy with CGM and switched to the AHCL system (MiniMedTM 780G, Medtronic, Northridge, CA, USA) between weeks 13 and 14. Results: The AHCL system improved glycemic control from weeks 14 to 26, achieving international guidelines with TIR = 72%, TAR = 24%, TBR = 4%. At week 30, TIR was 66%, TAR 31%. By altering diet and adding ‘fake carbohydrates’, she maintained TIR ≥ 70%, TBR ≤ 4%, TAR ≤ 26% from week 34 to birth. A healthy 4 kg, 53 cm baby boy was born at week 38. Conclusions: The use of the AHCL system holds significant promise for improving glycemic control in pregnancy. Optimal glycemic control with MiniMedTM 780G in pregnancy requires accurate carbohydrate counting, specific timing of insulin doses in relation to meal consumption and dietary choices that reduce the glycemic load of meals continue to be crucial factors in achieving optimal glycemic control during pregnancy using the MiniMedTM 780G system. Further research and clinical studies are needed to explore the full potential of these advanced systems in managing T1DM during pregnancy and optimizing maternal and neonatal outcomes.
The role of urban growth, climate change, and their interplay in altering runoff extremes

Changes in climate and urban growth are the most influential factors affecting hydrological characteristics in urban and extra‐urban contexts. The assessment of the impacts of these changes on the extreme rainfall–runoff events may have important implications on urban and extra‐urban management policies against severe events, such as floods, and on the design of hydraulic infrastructures.
An Account of Diversity of Pollinators from Bangladesh

This study explores the diversity, relative abundance, evenness, and richness of pollinators in the Rajshahi University Campus, in Bangladesh. A total of 625 individuals belonging to both invertebrates and vertebrates were recorded. Among the invertebrates, 44 insect species in five orders such as Hymenoptera, Diptera, Hemiptera, Coleoptera, and Lepidoptera were collected. The results revealed that the Lepidoptera and Hymenoptera were more abundant. Around 17 vertebrates in four orders, including Aves and Mammalia were also recorded. The diversity indices were: H'=3.82, with the Evenness (E=0.93), and Margalef’s Richness Index (d=9.32). Also 59 pollinator-visiting plants were enlisted.
FLORISTIC COMPOSITION AND DIVERSITY OF HOMEGARDENS IN ANGARA BLOCK, RANCHI, JHARKHAND

The study focused on the composition and diversity of plant species in homegarden of four selected villages of Angara block of Ranchi, Jharkhand. A total of 101 plant species (21 tree, 10shrubs, 13 sapling, 11 seedling and 46 herbs) belonging to 43 families were recorded. In the tree layer Verbenaceae, Rhamnaceae Anacardiaceae and Leguminosae in sapling layer Rhamnaceae, Verbenaceae and Anacardiaceae, in seedling layer, Rhamnacea,Verbenaceae and Moraceaein shrubs layer Caricaceae,Moringaceae and Verbenaceae were most dominant family. However, in herbs layer Poaceae, Brassicaceae, Solanaceae Cucurbitaceae and Malvaceae were most dominant family.Density of tree, sapling, seedling, shrubs and herbs were 840, 170,140,1160 and 102320 stems ha-1 respectively. The basal cover of tree, sapling, seedling, shrubs and herbs were39.26, 0.62, 0.62, 11.07 and 45.09 respectively. Diversity indices of different villages of study area the Shannon index of tree, sapling, seedling, shrubs and herbs were 3.46, 2.77, 2.50, 2.27 and3.67, respectively. Similarly, Simpson’s index of tree layer were 0.12 , sapling layer 0.17,sapling layer 0.18 , shrubs layer 0.25 and herb layer 0.11 and Species richness of the tree, sapling, seedling, shrub and herb were 2.22, 1.36,1.01, 0.72 and 1.91, respectively. Equitability were 1.24of tree layer, 1.33 of sapling layer, 1.40 of seedling layer, 1.27 of shrub layer, 1.17 of herb layer. Beta diversity lies between1.31 to 2.63S of the tree, sapling, seedling, shrub and herb layer. The practice of indigenous agroforestry homegarden is an integral component in Jharkhand and play crucial role in supplying vegetables, fruits, fuel wood, small timber, herbs and spices etc for their daily requirement. These homegardens serves as an important source of food and that also maintains productivity, protect natural resources, minimize environmental impacts and provide economic and social needs.
East Anatolian plateau constructed over a continental basement: No evidence for the East Anatolian accretionary complex

The East Anatolian plateau (Turkey) is extensively covered by Neogene to Quaternary volcanic-sedimentary rocks, and is characterized by an attenuated lithospheric mantle. Its pre-Neogene basement is commonly considered to consist entirely of Late Cretaceous to Oligocene oceanic accretionary complexes, formed at the junction of several continental blocks. Here we report on three main exposures of the pre-Neogene basement in this region. The exposed areas consist mainly of amphibolite-to granulite-facies metamorphic rocks, including marble, amphibolite, metapelite, metagranite, and metaquartzite. An upper amphibolite-to granulitefacies domain is equilibrated at similar to 0.7 GPa and similar to 800 degrees C at 83 +/- 2 Ma (2 sigma). U-Pb dating of magmatic zircons from the metagranite yielded a Late Ordovician-early Silurian protolith age (444 +/- 9 Ma, 2 sigma). The detrital zircons from one metaquartzite point to a Neoproterozoic-early Paleozoic provenance. Ophiolitic rocks tectonically sit on the metamorphic rocks. Both the metamorphic and ophiolitic rocks are in turn unconformably covered by lower Maastrichtian clastic rocks and reefal limestones, suggesting that the whole exhumation process and juxtaposition with the ophiolitic rocks had occurred by the early Maastrichtian. Several lines of evidence, such as (1) the absence of any indication of a former high-pressure metamorphism in the metamorphic rocks, (2) the allochthonous nature of the ophiolitic rocks, (3) the presence of metagranite with a Late Ordovician-early Silurian protolith age, and (4) the Neoproterozoic- early Paleozoic provenance of detrital zircons in the metaquartzite (in contrast to the dominance of late Paleozoic-Mesozoic crystalline rocks in the adjacent continental blocks) indicate a substantial component of continental basement beneath the Neogene to Quaternary cover. Thus, the loss of the lithospheric mantle probably resulted from lithospheric foundering processes beneath the plateau, rather than just slab steepening and break-off.
An Exploratory Overview of Teacher Educators’ Demographic Based Insight Regarding Standards of Quality of Teacher Education in Public Sector Universities of Pakistan

The quality of teacher education is highly contingent on professional standards and teachers’ firm belief in these standards. By following the standards, teacher education can be revolutionized. Keeping in view this utmost need of standards, the present study was envisioned to review teacher educator’s insight regarding standards of quality of teacher education. For this purpose, an exploratory survey was conducted with the help of an open ended questionnaire based on ten national professional standards. Two demographics gender and teachers’ designation were focused. Questionnaire was administered over 55 teacher educators out of which 49 questionnaire were returned. These teacher educators were purposively selected as they were teaching to preservice teachers in teacher education departments of various public sector universities of Punjab, KP and Federal. There were total 15 questions in this questionnaire. Results of the study concluded that majority of teachers were well aware of these standards. In all standards data showed a marginal gender based difference. However,in terms of training teachers revealed that there is lack of training regarding implementation of these standards. Teachers were found weak in standard of professional code of conduct and assessment techniques. Half of the majority of teachers were hopeful that standards can improve quality of teacher education. The study recommends training program for teachers for teachers’ continuous professional development and to empower them for using ICTs and for opting diverse assessment techniques.
How long and how frequent is sufficient? Long time study (2003-2022) of variation in occurrence, species richness and fructification of grassland-fungi in a semi-natural grassland in South-Western Norway

The semi natural grassland described in this paper, Hovaneset in Stord municipality, South-Western Norway, has been examined for grassland fungi for 20 years, from 2003 until today (2022). This has resulted in the discovery of 92 different species after a total of 180 visits to the locality. Change in the frequency of survey to approximately a weekly visit during the seasons from 2010 resulted in a large increase in species diversity, also of red-listed species. During these last 13 years of survey, the total number of species more than doubled, and the number of red-listed species more than tripled, which clearly shows the huge effect in changing the frequency of visits to a visit once a week during the season. The survey also clearly shows that the number of finds during a visit varies greatly from year to year and from week to week. In an optimal year for grassland fungi, around 70% of the species that grow there can be found in a weekly survey throughout the season, while a less good year gives a maximum of 40% finds. The survey also shows that the time of visit in a particular year is decisive for how many species are found in one visit. In an optimal year for grassland fungi, at the best possible match with time of survey, you can find up to 50% of the species growing there in one visit, but more likely it will be around 35%. It therefore shows very clearly that visits during the whole season is necessary to get hold on all fungi growing here. The survey also shows that many grassland fungi have very irregular fructification from one year to the other, which particularly applies to species within the genera Clavaria and Entoloma. Only ten species were found each year during the survey, most of which were waxcaps (Hygrocybe s.l.), while 14 species were only found in one of the years of survey. The time of fruiting also seems to have changed during the 20 years the survey has been ongoing. The week with the highest number of species recorded in 2021/22 is approximately 3-4 weeks later than it was in 2013/14. This is particularly clear for the genus Entoloma, which normally has an early and limited fruiting period.
An observation-based method to quantify the human influence on hydrological drought: upstream–downstream comparison

ABSTRACT In this present era of the Anthropocene, human activities affect hydrology and droughts. Quantifying this human influence improves our understanding and builds fundamental knowledge for water resource management. Analysis of observation data is useful in progressing this knowledge as these human activities and feedbacks are intrinsically included. Therefore, here we present an observation-based approach, the upstream–downstream comparison, to quantify changes in hydrological drought downstream of a human activity. We demonstrate this approach in a basin in northern Chile, where a reservoir was introduced. A sensitivity analysis is performed to assess how different choices of drought analysis threshold can affect the results and interpretation. We find that many commonly used choices do not exclude human activities from the threshold and therefore could be underestimating the change detected due to the human influence. The upstream–downstream comparison avoids this through the application of the upstream station threshold rather than the human-influenced downstream station.
Dispersion Characteristics From Simplified Dispersion Equation for Open Rectangular Planar Tape Helix

A rectangular open tape helix is analyzed for its dispersion characteristics that are numerically computed from the dispersion equation derived without any prior assumption of the current density distribution on the tape helix surface. The dispersion equation is a conjoint expression evaluated along the axial and transverse directions, obtained by applying the accurate boundary conditions to one-quarter of the structure. The dispersion characteristics are numerically computed for fundamental harmonic and a few higher-order modes after truncating an infinite number of simultaneous equations represented in the form of a determinantal representation: $\vert \textbf {A}\vert = \textbf {0}$ . Comparing the computed characteristics to those of the theoretical sheath helix model reveals that they are significantly different. The dispersion characteristics are numerically computed, and the phase velocity and interaction impedance are simulated for various dimensional variations of the structure. Plotted phase velocity and interaction impedance curves reveal the potential usability of such devices as compact traveling wave tubes that can be miniaturized and printed to operate at much higher frequencies than conventional TWTs.
Finite element modeling of tidal flow and bed -load transport in the Great Bay Estuarine system, New Hampshire

Current, sea level and bed-load transport are investigated in the Great Bay Estuary, New Hampshire---a shallow, well-mixed system with low freshwater input. Main channel tidal currents are over 2 m/sec, and its dynamic balance is dominated by the pressure gradient and bottom friction. Current and sea level forced by the M2, M4, M6 tides at the estuary mouth are simulated by two numerical models---a three-dimensional, harmonic model that solves the linearized shallow water equations (FUNDY5); and a vertically averaged, time stepping, non-linear model (ADAM). ADAM makes use of a kinematic assumption (that is, the local and advective accelerations are neglected) and accounts for flooding and dewatering over tidal flats by employing a groundwater component. FUNDY5 is used as a preliminary diagnostic tool to identify the general properties of the estuarine flow and to identify grid problems. ADAM is used as a prognostic model to simulate the tidal hydrodynamics of the estuarine system. The accuracy of the hydrodynamic predictions is evaluated by comparison with ten tidal elevation and four cross-section averaged current measurements. The results show that the kinematic assumption holds for the lower and middle sections of the estuary but fails in the upper sections, due in part to the increased importance of accelerations in these sections. Residuals (time averages) of currents are also investigated and yielded flood directed pathways over the shallow flats and ebb directed pathways in the deep channels. Currents simulated by ADAM are then used to model bed-load transport in the vicinity of a rapidly growing shoal located in the main channel of the lower system. Consisting of coarse sediments, the shoal must be dredged every 5--9 years. Two approaches are taken---an Eulerian parametric method in which elemental bedload flux vectors are calculated at each time step; and a Lagrangian particle tracking approach in which a finite number of sediment particles are released at different times in the M2 cycle and tracked. Both methods yield pathways and accumulations in agreement with the observed shoal formation and the long-term rate of sediment accumulation in the shoal area.
Effect of Tempeh and Daidzein on Calcium Status, Calcium Transporters, and Bone Metabolism Biomarkers in Ovariectomized Rats

Menopause marks a critical life stage characterized by hormonal changes that significantly impact bone health, leading to a heightened susceptibility to bone fractures. This research seeks to elucidate the impact of daidzein and tempeh on calcium status, calcium transporters, and bone metabolism in an ovariectomized rat model. Forty female Wistar rats, aged 3 months, participated in a two-phase experiment. The initial phase involved inducing a calcium deficit, while the second phase comprised dietary interventions across five groups: Sham (S) and Ovariectomy (O) with a standard diet, O with bisphosphonate (OB), O with pure daidzein (OD), and O with tempeh (OT). Multiple parameters, encompassing calcium levels, calcium transporters, bone histopathology, and serum bone metabolism markers, were evaluated. The findings revealed that the OT group showcased heightened levels of bone turnover markers, such as pyridinoline, C-telopeptide of type I collagen, bone alkaline phosphatase, and procollagen type I N-terminal propeptide, in contrast to S and O groups, with statistical significance (p < 0.05). Histopathologically, both the OD and OT groups exhibited effects akin to the OB group, indicating a decrease in the surface area occupied by adipocytes in the femoral bone structure, although statistically non-equivalent, supporting the directionally similar trends. Although TRPV5 and TRPV6 mRNA expression levels in the jejunum and duodenum did not display statistically significant differences (p > 0.05), the OD and OT groups exhibited increased expression compared to the O group. We hypothesized that obtained results may be related to the effect of isoflavones on estrogen pathways because of their structurally similar to endogenous estrogen and weak estrogenic properties. In conclusion, the daily consumption of pure daidzein and tempeh could potentially improve and reinstate calcium status, calcium transport, and bone metabolism in ovariectomized rats. Additionally, isoflavone products demonstrate effects similar to bisphosphonate drugs on these parameters in ovariectomized rats.
Spatial and temporal analysis of extreme bioclimate conditions in Vojvodina, Northern Serbia

Several indices, with focus on extreme climate and bioclimate events have been calculated and their trends (over 1961 to 2014) analyzed in order to identify possible changes in temperature‐related climate extremes over Vojvodina region, Northern Serbia. Physiologically equivalent temperature (PET) has been used for the assessment of bioclimatological extremes in Vojvodina. A number of indices for temperature extremes have been defined by CLIVAR (Climate Variability and Predictability) and they are modified in order to detect extremes in bioclimatological variables (PET). In this study, we used 11 PET indices. The results indicate that the whole area is dominated by significant increase in the frequency of warm conditions and significant decrease in the cold conditions. These results could indicate that the warming in Vojvodina could be due to the more pronounced and higher frequency of warm bioclimatological extreme conditions. The frequency and the duration of heat waves are increasing for the whole area, while the decrease in number and duration of cold waves is not so pronounced.
The mediating role of intention of learning behaviour in learning behaviour

Improving the quality of postgraduate study is one that must be addressed with the increase in the number of postgraduate students. This study aims to analyse the effects of learning attitude, learning motivation and self-efficacy on learning behaviour through the intention of learning behaviour, and the effect of learning behaviour on learning outcome. Measurements were made on 560 postgraduate students after the development of a scale. The scale was analysed for reliability and exploratory factor analysis using SPSS software. The date were then analysed using structural equation modelling (SEM) analysis techniques with path analysis and bootstrap methods. The results of the study showed that students’ attitudes towards learning and self-efficacy had a significant indirect on learning behaviour through the mediating involvement of intention to learn behaviours, and learning behaviour had a significant effect on learning outcome. Therefore, there is a need to improve learning behaviour by improving students’ intention to learn behaviour so that they can have good learning outcome.
Magnetic Hyperthermia Therapy for High-Grade Glioma: A State-of-the-Art Review

Magnetic hyperthermia therapy (MHT) is a re-emerging treatment modality for brain tumors where magnetic nanoparticles (MNPs) are locally delivered to the brain and then activated with an external alternating magnetic field (AMF) to generate localized heat at a site of interest. Due to the recent advancements in technology and theory surrounding the intervention, clinical and pre-clinical trials have demonstrated that MHT may enhance the effectiveness of chemotherapy and radiation therapy (RT) for the treatment of brain tumors. The future clinical success of MHT relies heavily on designing MNPs optimized for both heating and imaging, developing reliable methods for the local delivery of MNPs, and designing AMF systems with integrated magnetic particle imaging (MPI) for use in humans. However, despite the progression of technological development, the clinical progress of MHT has been underwhelming. This review aims to summarize the current state-of-the-art of MHT and offers insight into the current barriers and potential solutions for moving MHT forward.