Miracle-dz/UniFAR-FTUs huggingface dataset:
Preliminary Study of the Bactericide Properties of Biodegradable Polymers (PLA) with Metal Additives for 3D Printing Applications

Plastic is a highly used material in various sectors. Due to its plentiful availability in the environment, microorganism surface contamination is a risk. The aim of this work is to achieve bactericidal capacity in plastics that reduces the microorganism’s colonization risk and, consequently, reduces the chances of having an infection with E. coli and Listeria monocytogenes bacteria. Using polylactic acid (PLA) as the polymeric matrix, mixtures in concentrations of metal additive of ions of silver (Ag) R148 and S254 in 1% and 2% have been studied and manufactured. The materials are developed on an industrial scale through a process that proceeds as follows: (I) a mixture of polymer and additive in a double-screw compounder to obtain the compound in different concentrations, (II) the manufacture of filaments with a single-screw extruder, (III) 3D printing parts. Therefore, materials are evaluated in the form of powder, pellets and printed pieces to ensure their antibacterial effectiveness throughout the manufacturing process. The results of the research show antibacterial effectiveness for E. coli and Listeria monocytogenes of metal additives and polymeric compounds for all manufacturing phases on an industrial scale, with the effectiveness for additive R148 predominating at a concentration of 2%, demonstrating its microbial efficacy on surfaces with potential application in medicine.
Eating Vegetables First Regardless of Eating Speed Has a Significant Reducing Effect on Postprandial Blood Glucose and Insulin in Young Healthy Women: Randomized Controlled Cross-Over Study

People with fast eating habits have been reported to have an increased risk of diabetes and obesity. To explore whether the speed of eating a test meal (tomato, broccoli, fried fish, and boiled white rice) influences postprandial blood glucose, insulin, triglyceride, and free fatty acid levels, 18 young, healthy women consumed a 671 kcal breakfast at fast speed (10 min) and slow speed (20 min) with vegetables first and slow speed (20 min) with carbohydrate first on three separate days. This study was conducted using a within-participants cross-over design in which all participants consumed identical meals of three different eating speeds and food orders. Significant ameliorations of both fast and slow eating with vegetables first regimen on postprandial blood glucose and insulin levels at 30 and 60 min were observed compared with those of slow eating with carbohydrates first. In addition, the standard deviation, large amplitude of excursion, and incremental area under the curve for blood glucose and insulin in both fast and slow eating with vegetables first were all significantly lower than those of slow eating with carbohydrate first. Interestingly, there was no significant difference between fast and slow eating on postprandial blood glucose and insulin levels as long as vegetables were consumed first, although postprandial blood glucose at 30 min was significantly lower in slow eating with vegetables first than that of fast eating with the same food order. These results suggest that food order with vegetables first and carbohydrate last ameliorates postprandial blood glucose and insulin concentrations even if the meal was consumed at fast speed.
The Assessment of Multiplex PCR in Identifying Bacterial Infections in Patients Hospitalized with SARS-CoV-2 Infection: A Systematic Review

Bacterial infection can occur in patients hospitalized with SARS-CoV-2 in various conditions, resulting in poorer outcomes, such as a higher death rate. This current systematic review was conducted in order to assess the efficiency of multiplex PCR in detecting bacterial infections in hospitalized COVID-19 patients, as well as to analyze the most common bacterial pathogens and other factors that interfere with this diagnosis. The research was conducted using four electronic databases (PubMed, Taylor&Francis, Web of Science, and Wiley Online Library). Out of 290 studies, nine were included in the systematic review. The results supported the use of multiplex PCR in detecting bacteria, considering its high sensitivity and specificity rates. The most common bacterial pathogens found were Klebsiella pneumoniae, Staphylococcus aureus, Pseudomonas aeruginosa, Streptococcus pneumoniae, and Haemophilus influenzae. The median age at admission was 61.5 years, and the majority of patients were men (70.3%), out of a total of 1553 patients. The proportion of ICU admission was very high, with a pooled proportion of 52.6% over the analyzed studies, and an average duration of hospitalization of 13 days. The mortality rate was proportionally high, as was the rate of ICU admission, with a pooled mortality of 24.9%. It was discovered that 65.2% of all patients used antibiotics before admission, with or without medical prescription. Antibiotic treatment should be considered consciously, considering the high risks of developing antibiotic resistance.
An Analysis of Television Satire on Kiky Saputri’s Roasting in Lapor Pak!

Humor has always been and will remain to be part of the political landscape, even though it may take a temporary break from time to time. The range of political humor is immense, including roasting comedy. In general, past research has succeeded in showing the importance of roasting comedy and how it employs the figure of speech. The problem is although the roasting is broadcast on national television, none of them has examined it using the theory of television satire. Thus, this research aimed to analyze the presupposition of roasting comedy and to study the roasting comedy by using the heuristic structures of television satire, which include: space, target, rhetoric, media, and time. The writers used qualitative methods to analyze the data using critical discourse analysis (CDA). This study used Kiky Saputri’s roasting video of DKI Jakarta governor Anies Baswedan in Lapor Pak! comedy program. The video was taken from the YouTube account Trans7 Official entitled “Kiky ROASTING Anies Baswedan, Pasukan Auto Jantungan! | LAPOR PAK! (09/11/21) Part 4”. This program was selected for its popularity and has won the Indonesian Television Award (ITA) 2021 in the most popular non-drama primetime program category. Among the program's episodes, this episode has become viral with more than 6.8 million views and was widely published in major national news portals. From the analysis, it can be concluded that Kiky Saputri’s roasting comedy has a specific pattern. Furthermore, because the Lapor Pak! program fulfilled Jones' heuristic structure, Kiky Saputri's roasting Anies Baswedan attracted much attention.
Which Patients with Carpal Tunnel Syndrome are More Associated with Fibromyalgia Syndrome?

Objective: In this study, it was aimed to detect the presence of Fibromyalgia Syndrome (FMS) and related factors in patients diagnosed by Carpal Tunnel Syndrome (CTS). Materials and Methods: Demographic data and the features of CTS were noted by applying face-to-face questionnaire method. The existence of FMS in patients with CTS was investigated using the 2016 American College of Rheumatology (ACR) Fibromyalgia Diagnostic criteria. The Fibromyalgia Impact Questionnaire (FIQ) was introduced to patients diagnosed with FMS. Then, the correlations between the incidence of FMS in CTS patients, the presence of FMS and the hand with CTS, the severity of CTS and the existence of FMS, the presence of FMS and the duration of CTS symptoms, and finally CTS severity and FIQ were concurrently examined. Results: 151 patients included in the study. Bilateral CTS was detected in 89 (58.9%) patients. CTS was mild in 55 (36.4%), moderate in 87 (57.6%), and severe in 9 (6.0%) patients. Concomitant FMS was detected in 73 (48.3%) of all CTS patients. FMS rate is higher in patients with bilateral CTS (p=0.001). No significant relevance was observed between the severity of CTS and the presence of FMS (p = 0.864). The median duration of CTS symptoms with FMS patients was 24 (1-240) months; this period was found to be 12 (1-120) months in those without FMS. No significant relations between the presence of FMS and the duration of CTS symptoms were encountered (p = 0.073). The severity of CTS and FIQ demonstrated no significant difference (p=0.955). Conclusion: The case of FMS is high in specially bilaterally CTS patients. The fact that there may be common points in the pathogenesis of these two diseases suggests that it should be considered for diagnosis and treatment.
On the Advent of Super-Resolution Microscopy in the Realm of Polycomb Proteins

Simple Summary The genomes of metazoans are organized at multiple spatial scales, ranging from the double helix of DNA to whole chromosomes. The intermediate genomic scale of kilobases to megabases, which corresponds to the 50–300 nm spatial scale, is particularly interesting because the tridimensional arrangement of chromatin is implicated in multiple regulatory mechanisms. Indeed, a crucial hallmark of cellular life is the widespread ordering of many biological processes in nano-/mesoscopic domains (10–200 nm), which now may be revealed by an imaging toolbox referred to as super-resolution microscopy. In this context, polycomb proteins stand as major epigenetic modulators of chromatin function, acting prevalently as repressors of gene transcription. This work reviews the current state-of-the-art super-resolution microscopy applied to polycomb proteins. Of note, super-resolution data have complemented cutting-edge molecular biology methods in providing a rational framework for understanding how polycomb proteins may shape 3D chromatin topologies and functions. Abstract The genomes of metazoans are organized at multiple spatial scales, ranging from the double helix of DNA to whole chromosomes. The intermediate genomic scale of kilobases to megabases, which corresponds to the 50–300 nm spatial scale, is particularly interesting, as the 3D arrangement of chromatin is implicated in multiple regulatory mechanisms. In this context, polycomb group (PcG) proteins stand as major epigenetic modulators of chromatin function, acting prevalently as repressors of gene transcription by combining chemical modifications of target histones with physical crosslinking of distal genomic regions and phase separation. The recent development of super-resolution microscopy (SRM) has strongly contributed to improving our comprehension of several aspects of nano-/mesoscale (10–200 nm) chromatin domains. Here, we review the current state-of-the-art SRM applied to PcG proteins, showing that the application of SRM to PcG activity and organization is still quite limited and mainly focused on the 3D assembly of PcG-controlled genomic loci. In this context, SRM approaches have mostly been applied to multilabel fluorescence in situ hybridization (FISH). However, SRM data have complemented the maps obtained from chromosome capture experiments and have opened a new window to observe how 3D chromatin topology is modulated by PcGs.
Do social influences, awareness, or experience matter? Toward a better understanding of Farm-related Injury Risk Perception among agricultural science college students in Ireland

Introduction Formal farm safety education/training should be tailored, in terms of the approach, content and delivery, to students undertaking agriculture education and training to enhance Farm-related Injury Risk Perception (FIRP). To this end, this paper assesses factor(s) explaining or predicting levels of FIRP amongst students studying for a degree in agriculture science. Methods A cross-sectional online survey was conducted with a nationally representative sample of Bachelor of Agriculture Science (BAgrSc) students (N = 417) (aged 18–20) in Ireland. Descriptive [frequency and cross-tabulations) and inferential (Ordinal Logistic Regression (OLR)] analyses were applied to evaluate the effects of social influences, experience (of farming, of a near-miss or injury), and awareness (of others who were injured or killed on the farm) on FIRP. Results The study found that social influences negatively affected FIRP (P < 0.05). A relatively small number of students reported experiencing an injury (n = 56, 13.4%) that resulted in them being unable to participate in educational or social activities. A quarter of the respondents did, however, record experiencing a near-miss/close call (n = 106, 25.4%). A notable proportion (n = 144, 34.5%) of students had personal connections to someone who died as a consequence of a farm-related incident and 56.4% (n = 235) knew someone who was moderately or severely injured. OLR findings established that experiencing a severe injury, having a near-miss or close call, and awareness of a farm-related death or injury positively affects FIRP (P < 0.05). Conclusions Perception of farm risks amongst students in Ireland is low. Students who recorded higher levels of risk perception were, however, more likely to report experiencing a near-miss, close call or severe injury, or knowing someone who experienced a farm-related injury or fatality. Farmers, family or friends were found to negatively impact the FIRP and this reflects previous research findings. Our findings highlight the need for education and training programs to enhance opportunities for student peer-to-peer learning through sharing of experiences and/or knowledge of farm injuries and/or fatalities. Such activities will enhance awareness and understanding amongst the general population of students leading to increased FIRP and contribute to a reduction in risk-taking.
A study of advanced high-loaded transonic turbine airfoils

The development of high-performance turbine airfoils has been investigated under the condition of a supersonic exit Mach number. In order to obtain a new aerodynamic design concept for a high-loaded turbine rotor blade, we employed an evolutionary algorithm for numerical optimization. The target of the optimization method, which is called evolutionary strategy (ES), was the minimization of the total pressure loss and the deviation angle. The optimization process includes the representation of the airfoil geometry, the generation of the grid for a blade-to-blade computational fluid dynamics analysis, and a two-dimensional Navier-Stokes solver with a low-Re k-e turbulence model in order to evaluate the performance. Some interesting aspects, for example, a double shock system, an early transition, and a redistribution of aerodynamic loading on blade surface, observed in the optimized airfoil, are discussed. The increased performance of the optimized blade has been confirmed by detailed experimental investigation, using conventional probes, hotfilms, and L2F system.
GALAXY COLORS IN VARIOUS PHOTOMETRIC BAND SYSTEMS

A study is made of stellar and galaxy colors using a spectrophotometric synethesis technique. We show that use of good color response functions and a modern determination of the spectroscopic energy distribution for a alpha-Lyr gives synthetic colors in a good agreement with photometric observations to about 0.05 mag. The synthetic method then is applied to sutdy galaxy colors using the spectrophotometric atlas of Kennicutt (1992), and a comparison is made with observed galaxy colors. The K-correction is calculated and compared with that of Coleman, Wu and Weedman (1980). We then study colors of galaxies in various photometric band systems and obtain color transformation laws, which enable us to find offsets among different systems. We include 48 photometric bands in our study.
Effect of tapering on natural frequencies of rotating beams

The problem of free vibration of a rotating tapered beam is investigated by developing explicit expressions for the mass, elastic and centrifugal stiffness matrices in terms of the taper ratios. This investigation takes into account the effect of tapering in two planes, the effect of hub radius as well as the stiffening effect of rotation. The equations of motion are derived; the associated generalized eigenvalue problem is defined in conjunction with a suitable Lagrangian form and solved for a wide range of parameter changes. The effect of tapering on the natural frequencies of the beam is examined with all parameter changes present. Results are compared with those available in literature and are found to be in excellent agreement.
The magnetic field structure of a snowflake divertor

The snowflake divertor exploits a tokamak geometry in which the poloidal magnetic field null approaches second order; the name stems from the characteristic hexagonal, snowflakelike shape of the separatrix for an exact second-order null. The proximity of the poloidal field structure to that of a second-order null substantially modifies edge magnetic properties compared to the standard X-point geometry (with a first-order null); this, in turn, affects the edge plasma behavior. Modifications include: (1) The flux expansion near the null-point becomes 2–3 times larger. (2) The connection length between the equatorial plane and divertor plate increases. (3) Magnetic shear just inside the separatrix becomes much larger. (4) In the open-field-line region, the squeezing of the flux-tubes near the null-point increases, thereby causing stronger decoupling of the plasma turbulence in the divertor legs and in the main scrape-off layer. These effects can be used to reduce the power load on the divertor plates and/or .
Effect of Sliding Friction on Contact Stresses in a Rectangle Compressed by Rigid Planes

double Fourier transforms. Although the author hasn't proven a theorem for the justification of the method (particularly as to the question of completeness), he has given it considerable thought and he believes that the method should work. The nonexistence, of course, of such a theorem is certainly no evidence that the method is not applicable. Be that as it may, the question is an important one which eventually will have to be answered. But then Professor Benthem's work (see discussion reference [4]) may also be subject to the same criticism inasmuch as the author has not proven completeness and furthermore whether the problem admits a solution in a separable form, particularly in 8 and 0. 2 Due to the space requirements that the Journal imposes, the author was obligated to restrict himself to a short and formal discussion of the method thus sacrificing mathematical rigor. One, however, if he so desires, may investigate the question of whether the displacement and stress functions (52)-(61) are meaningful. 3 From the statement of the paragraph following equation (77), it is clear that the exact value of the coefficients Aj-^ must be determined from equations (72) and (75). However, due to insufficient research funds, the author had no other alternative but to truncate the system (72) for k = j = 0. While we have no (mathematical) error analysis for the justification of the truncation per se, we have (numerically) studied the system carefully and have found plenty of evidence that equation (78) does represent the main contribution. However, it should be emphasized that equation (79) which leads to the author's three-dimensional singularities involves no truncation whatsoever. Be that as it may, the author well recognizes the fact that the coefficients 4„' should inevitably be computed exactly. However, we have not as yet been successful in securing the necessary research funds to complete this and other important questions of the foregoing problem.
Polarization singularities in isotropic random vector waves

Following Nye & Hajnal, we explore the geometry of complex vector waves by regarding them as a field of polarization ellipses. Singularities of this field are the C lines and L lines, where the polarization is purely circular and purely linear, respectively. The singularities can be reinterpreted as loci of photon spin 1 (C lines) and 0 (L lines). For Gaussian random superpositions of plane waves equidistributed in direction but with an arbitrary frequency spectrum, we calculate the density (length per unit volume) of C and L lines.
Prevention of Pregnancy Loss: Combining Progestogen Treatment and Psychological Support

Pregnancy loss can be defined as a loss before either 20 or 24 weeks of gestation (based on the first day of the last menstrual period) or the loss of an embryo or fetus less than 400 g in weight if the gestation age is unknown. Approximately 23 million pregnancy losses occur worldwide every year, equating to 15–20% of all clinically recognized pregnancies. A pregnancy loss is usually associated with physical consequences, such as early pregnancy bleeding ranging in severity from spotting to hemorrhage. However, it can also be associated with profound psychological distress, which can be felt by both partners and may include feelings of denial, shock, anxiety, depression, post-traumatic stress disorder, and suicide. Progesterone plays a key part in the maintenance of a pregnancy, and progesterone supplementation has been assessed as a preventative measure in patients at increased risk of experiencing a pregnancy loss. The primary objective of this piece is to assess the evidence for various progestogen formulations in the treatment of threatened and recurrent pregnancy loss, postulating that an optimal treatment plan would preferably include a validated psychological support tool as an adjunct to appropriate pharmacological treatment.
Characterization of surface-exposed structural loops as insertion sites for foreign antigen delivery in calicivirus-derived VLP platform

Chimeric virus-like particles (cVLPs) show great potential in improving public health as they are safe and effective vaccine candidates. The capsid protein of caliciviruses has been described previously as a self-assembling, highly immunogenic delivery platform. The ability to significantly induce cellular and humoral immunity can be used to boost the immune response to low immunogenic foreign antigens displayed on the surface of VLPs. Capsid proteins of caliciviruses despite sequence differences share similar architecture with structural loops that can be genetically modified to present foreign epitopes on the surface of cVLPs. Here, based on the VP1 protein of norovirus (NoV), we investigated the impact of the localization of the epitope in different structural loops of the P domain on the immunogenicity of the presented epitope. In this study, three distinct loops of NoV VP1 protein were genetically modified to present a multivalent influenza virus epitope consisting of a tandem repeat of M2/NP epitopes. cVLPs presenting influenza virus-conserved epitopes in different localizations were produced in the insect cells and used to immunize BALB/c mice. Specific reaction to influenza epitopes was compared in sera from vaccinated mice to determine whether the localization of the foreign epitope has an impact on the immunogenicity.
Connectedness structure of Pan-European Equity REITs

ABSTRACT This paper examines the interconnectedness among European equity REITs (Real Estate Investment Trusts) due to increased financialization of the real estate sector and European economic integration. It uses two models, Diebold and Yilmaz's generalised variance decomposition and Barunik and Krehlik's time-frequency dynamics framework. The study covers a sample of 42 Pan-European REITs over a 15-year period from 2004 to 2018 and finds that the connectedness among REITs is influenced by the geographical location and performance of commercial real estate sub-sectors. The dynamic analysis shows that the source of shocks does not determine the persistence, but rather how the markets interpret the shocks during high-frequency intervals. The paper concludes that the connectedness structure among REITs reflects uncertainty interaction, with some effects observed mainly at high frequency levels, and few unexpected shocks found in the long-term stability of REIT returns.