Miracle-dz/UniFAR-FTUs huggingface dataset:
Determination of coagulopathy complicating severe preeclampsia and eclampsia with platelet count

Background: Preeclampsia is a dangerous complication which occurs potentially in pregnancy and is characterised by high blood pressure. It effects maternal and perinatal health and is complicated by abnormalities of coagulation. The aim of the study was to determine platelet count which predicted coagulopathy in patients with severe preeclampsia and eclampsia.Methods: Prospective cohort study done in all patients were admitted with diagnosis of severe preeclampsia and eclampsia and admitted for stabilisation. Blood samples were collected from all patients for detecting bleeding, clotting time, electrolytes, urea and creatinine, liver functions tests, full blood count, platelet count, prothrombin time, activated partial thromboplastin time and plasma fibrinogen level in 100 patients in total. Using chi square test, univariate analysis was conducted.Results: Out of 100 women patients, 70 (70%) patients had severe preeclampsia and 30 (30%) patients had eclampsia out of which 15 patients had thrombocytopenia. The incidence of thrombocytopenia among patients was 16.6%. Biochemical coagulopathy was noted in 7%. Patients with severe preeclampsia had platelet count of 185000±61289 per µl, PT was 13.52±1.48 sec, APTT was 34.52±2.49 sec and fibrinogen was 3.16±0.22 g/dl. Patients with eclampsia (with thrombocytopenia) had platelet count of 79528±14897 per µl, PT was 19.25±5.28 sec, APTT was 37.08±5.33 sec and fibrinogen was 2.67±0.53 g/dl. Thrombocytopenia was complicated with eclampsia and it was associated with biochemical coagulopathy which made the condition more severe.Conclusions: 80000 cells/µl is the thrombocytopenia level which is considered to be critical in severe preeclampsia and eclampsia. This will help to reduce maternal and perinatal mortality and morbidity rates.
Local tunability in a multi-port SQUID by an injection current

The tunability in Josephson junctions is foundational to the superconducting classical and quantum applications. Here, we demonstrate the local manipulation of supercurrent realized in a superconducting quantum interference device (SQUID) with two Nb/TiO x /Nb Josephson junctions that is biased at the TiO x layer. Our measurements indicate that the multi-port device allows for an easy and in situ tunability of the supercurrent. The control mechanism can be finely explained by simple yet valid theoretical methods, which take an effective electronic temperature across the SQUID and the self inductive magnetic flux into account. Furthermore, we show that the phase difference and kinetic inductance of this device can be tuned locally via the injection current. Thus, the device provides perspective for several superconducting electronics such as tunable superconducting circuits, sensitive magnetometry, and fast digital elements.
The Effect of Brand Relationship Quality on Post Purchase Loyalty on Premium Online Learning and Tutoring

In 2018, Indonesia Digital Education and E-Learning Market Outlook issued a report entitled "Rising Trend of Blended to Drive The Future Growth", the shown result was quite surprising because Indonesia was predicted to be the Top 5 Buyers of mobile learning products and services, competing with superpower countries such as China, the United States, together compete with developing countries such as Brazil and India. The total expenditure used to provide digital-based education in Indonesia has also increased in the last five years. The E-learning industry in Indonesia is highly developed. Start-up companies from within and outside the country produce online learning and tutoring with varied learning methods. One of the local online learning and tutoring provider that is having swift moves is Ruang Guru. However, competition between brands is enough to enter a reasonably intense phase. When a company invests in acquiring users, there will be a significant effort for customer retention, especially the usage of premium online learning and tutoring is set as a periodic subscription. This study analyzes the effect of brand relationship elements (satisfaction, commitment, and trust) on brand loyalty after purchasing. Using Partial Least Square as a data processing method. The study results show a significant positive effect of trust, satisfaction, and commitment to one element of brand loyalty, namely repurchase intention. In contrast, no significant positive effect between trust, satisfaction, and commitment with price tolerance will later be discussed in the discussion.
Antibiotic selection and risk profiles in patients receiving antibacterial cardiovascular implantable electronic device envelopes – a real world sample and analysis

The use of a cardiovascular implantable electronic device (CIED) envelope impregnated with antibiotics provides short-term local antibiotic delivery in the implant pocket and may lower infection risk. Biologic antibacterial (BIO) envelopes, such as the porcine extracellular matrix (ECM) device hydrated with antibiotics, facilitate active remodeling of the pocket into vital, vascularized tissue and provide short-term local antibiotic delivery. Limited clinical data is available on real-world clinician patient selection criteria, antibiotic choices, or clinical outcomes. To explore antibiotic hydration solution physician choices with respect to patient profiles, and to determine post-implant infection outcomes in patients receiving a CIED BIO envelope. A post-hoc sub-analysis of a multicenter, non-randomized study of 1017 patients receiving a biologic envelope (hydrated with or without antibiotics) during CIED procedures (SECURE Study) assessed antibiotic hydration choices, patient risk profiles, and the type and timing of infection for days 0–90 post procedure. Patient selection and antibiotic hydration choice were at the discretion of the treating physician. 850 patients received BIO envelopes, with a mean age of 71.9 years, and 60.5% having ≥2 standard infection risk factors. High power devices accounted for 47.6% and reoperations for 44.0% of the procedures. Antibiotic choice for envelope hydration prior to implantation is described in Table 1 below. Also, antibiotic combinations with gentamicin were used in 18.1% and other antibiotic combinations in 9.2% of patients. Patients receiving gentamicin hydrated BIO envelopes (BIO+G) trended toward fewer pocket infections vs. those without gentamicin (BIO-G) (0.0% vs. 1.6%, p=0.070) but the overall pocket infection rate of 1.2% was not significantly different based upon antibiotic choice. In a multivariate logistic regression model designed to predict the total infection rate, the use of gentamicin was associated with a 3-fold reduction in likelihood of infection, OR 3.0 (1.0–10.0); AUC=0.70. No differences in overall infection rates among patients undergoing lead or pocket revision only procedures (0.0% vs. 0.0%) or other major adverse events were observed based upon antibiotic usage. Real world clinical decision-making regarding antibiotic choice for biologic antibacterial envelopes varies among implanting clinicians and influences observed outcomes. The use of biologic antibacterial envelopes hydrated with gentamicin was associated with a lower likelihood of infection within 90 days when compared to biologic envelopes hydrated without gentamicin. Clinical trials to optimize patient selection processes and determine the best antibiotic choice when employing a CIED envelope merit further investigation. Type of funding sources: Other. Main funding source(s): The work was supported by Aziyo Biologics, Inc. Table 1. BIO Envelope Hydration
Identification of Three Novel PmGRI1 Genomic Resistance Islands and One Multidrug Resistant Hybrid Structure of Tn7-like Transposon and PmGRI1 in Proteus mirabilis

The widespread use of antibiotics in large-scale livestock production has led to serious antibiotic resistance. Proteus mirabilis is an important pathogenic bacterium on large-scale farms. Chromosomally localized mobilizable genetic elements (genomic islands) and mobile genetic elements (Tn7-like transposons) play an important role in the acquisition and transmission of resistance genes by P. mirabilis. To study the prevalence and resistance characteristics of antibiotic-resistant genomic islands in P. mirabilis of animal origin in China, we performed whole genome sequencing of P. mirabilis isolated from large-scale pig and chicken farms. Three new variants of PmGRI1 (HN31, YN8, and YN9), and a hybrid structure (HN2p) formed by the multidrug-resistant Tn7-like-HN2p transposon and a genomic island PmGRI1-HN2p, were identified from P. mirabilis. All variants underwent homologous recombination mediated by insertion sequence IS26. A genomic rearrangement in the chromosome between the Tn7-like-HN2p transposon and PmGRI1-HN2p occurred in HN2p. The heterozygous structure contained various antimicrobial resistance genes, including three copies of fluoroquinolone resistance gene qnrA1 and 16S rRNA methylase gene rmtB, which are rarely found in P. mirabilis. Our results highlight the structural genetic diversity of genomic islands by characterizing the novel variants of PmGRI1 and enrich the research base of multidrug resistance genomic islands.
Fungal biomarkers are detectable in Martian rock-analogues after space exposure: implications for the search of life on Mars

Mars is a primary target of astrobiological interest: its past environmental conditions may have been favourable to the emergence of a prebiotic chemistry and, potentially, biological activity. In situ exploration is currently underway at the Mars surface, and the subsurface (2 m depth) will be explored in the future ESA ExoMars mission. In this context, BIOlogy and Mars EXperiment was performed to evaluate the stability and detectability of organic biomarkers under space and Mars-like conditions. Our data suggested that some target molecules, namely melanin, azelaic acid and nucleic acids, can be detected even after 16 months exposure to Low Earth Orbit conditions by multidisciplinary approaches. We used the same techniques as onboard the ExoMars rover, as Raman and infrared spectroscopies and gas chromatograph-mass spectrometer, and polymerase chain reaction even if this is not planned for the imminent mission to Mars. These results should be taken into account for future Mars exploration.
Functional Connectivity at Rest between the Human Medial Posterior Parietal Cortex and the Primary Motor Cortex Detected by Paired-Pulse Transcranial Magnetic Stimulation

The medial posterior parietal cortex (PPC) is involved in the complex processes of visuomotor integration. Its connections to the dorsal premotor cortex, which in turn is connected to the primary motor cortex (M1), complete the fronto-parietal network that supports important cognitive functions in the planning and execution of goal-oriented movements. In this study, we wanted to investigate the time-course of the functional connectivity at rest between the medial PPC and the M1 using dual-site transcranial magnetic stimulation in healthy humans. We stimulated the left M1 using a suprathreshold test stimulus to elicit motor-evoked potentials in the hand, and a subthreshold conditioning stimulus was applied over the left medial PPC at different inter-stimulus intervals (ISIs). The conditioning stimulus affected the M1 excitability depending on the ISI, with inhibition at longer ISIs (12 and 15 ms). We suggest that these modulations may reflect the activation of different parieto-frontal pathways, with long latency inhibitions likely recruiting polisynaptic pathways, presumably through anterolateral PPC.
Alterations in Leg Muscle Glucose Uptake and Inter-Limb Asymmetry after a Single Session of tDCS in Four People with Multiple Sclerosis

Asymmetrical lower limb weakness is an early symptom and significant contributor to the progressive worsening of walking ability in people with multiple sclerosis (PwMS). Transcranial direct current stimulation (tDCS) may effectively increase neural drive to the more-affected lower limb and, therefore, increase symmetrical activation. Four PwMS (1 female, age range: 27–57) underwent one session each of 3 mA or SHAM tDCS over the motor cortex corresponding to their more-affected limb followed by 20 min of treadmill walking at a self-selected speed. Two min into the treadmill task, the subjects were injected with the glucose analog [18F]fluorodeoxyglucose (FDG). Immediately after treadmill walking, the subjects underwent whole-body positron emission tomography (PET) imaging. Glucose uptake (GU) values were compared between the legs, the spatial distribution of FDG was assessed to estimate glucose uptake heterogeneity (GUh), and GU asymmetry indices (AIs) were calculated. After tDCS, GU was altered, and GUh was decreased in various muscle groups in each subject. Additionally, AIs went from asymmetric to symmetric after tDCS in the subjects that demonstrated asymmetrical glucose uptake during SHAM. These results indicate that tDCS improved GU asymmetries, potentially from an increased neural drive and a more efficient muscle activation strategy of the lower limb in PwMS.
The Leontief Model in Research into the Economic Importance of Small Seaports: A Case Study

: Purpose: The article defines the economic importance of the seaport of Kołobrzeg, a local port located in the western part of the Polish Baltic coast. The study has distinguished three effects, direct, indirect, and induced, which constitute a full spectrum of the seaport's impact. The effects were discussed in terms of the output, the gross wages, and the employment figure. The subject matter discussed in the article is an introduction to a more extensive study, which is to be conducted on a representative group of local seaports. Design/Methodology/Approach: The port's significance in Kołobrzeg was determined using the Leontief model. The scope of the economic impact of the port was related to the Koszaliński subregion, a territorial unit at the NUTS 3 level. Regionalization of the national input-output table was performed using the Flegg Location Quotient (FLQ). The study was based on available statistical data, information obtained from the Main Statistical Office (GUS), and survey results. Findings: The importance of the port of Kołobrzeg is determined by the multiplier value, which is lower than in previous studies due to the reference area being narrowed down, and by the use of the FLQ formula reducing the self-supplying ability of the Koszalin subregion. The induced and direct effects had the most significant impact on the economy of the subregion, with the indirect effect being of a minor significance. Practical Implications: The study provides the decision-makers with information on the scope of impact and the economic significance of the Kołobrzeg port. They allow for a concentration of investment funds in the areas with the most significant impact on the local economy. the case of Polish seaports, no author has comprehensively determined their economic importance.
Diversity of Hesperiidae, Pieridae and Papilionidae Butterflies (Lepidoptera, Papilionoidea) in the mountain massif Shkoza in Kosovo

In this paper we present the results of a survey of three butterfly families: Hesperiidae, Pieridae and Papilionidae, in the Mountain massif Shkoza in central Kosovo, conducted from May to October 2016. Among 29 recorded butterfly species in this survey, 14 (48%) species belong to Pieridae, 10 (24%) to Hesperiidae and 4 (13.7%) to Papilionidae. Recorded species belong to five faunal elements according to Kudrna, Pennestorfer & Lux (2015) (KPS): 14 are Euro-Siberian (ES), 10 are Euro-Oriental (EO), two species are Mediterranean (EM), two are Holarctic (Hol) and one Boreo-Montane. Regarding the IUCN Red list status (van Swaay et al., 2010), three species Carcharodus floccifera (Zeller, 1847), Thymelicus acteon (Rottemburg, 1775) and Parnassius mnemosyne (Linnaeus, 1758) are Near Threatened (NT), while the other 27 are of Least Concern (LC). From our results we can conclude that the massif Shkoza has a well developed butterfly fauna, however further research is needed to have a complete picture of its diversity.
The Analysis of Brand Image and Brand Awareness on Purchase Decisions

The study aims to determine the effect of brand image and brand awareness on purchase decisions on Mayoutfit Bandung's consumers. The population in this study were all Mayoutfit Bandung Consumers. The sampling technique uses a simple random sampling method with a total sampling of 50 people. The measurement scale uses a Likert scale with multiple regression tests using the program application SPSS 16.0 for data analysis. Hypothesis testing using T-test shows that brand image positively affects purchasing decisions of 3,800; a significance value of 0.0000 < 0.05, and a regression coefficient of 0.146. Meanwhile, brand awareness has a positive effect on purchasing decisions of 3.862, a significance value of 0,000 < 0.005, and a regression coefficient of 0.606. Hypothesis testing using the f-test shows that the brand image and brand awareness variables influence purchasing decisions by 21%, with the remaining 79% influenced by other variables.
SLOGAN: SDC probability estimation using structured graph attention network

The trend of progressive technology scaling makes the computing system more susceptible to soft errors. The most critical issue that soft error incurs is silent data corruption (SDC) since SDC occurs silently without any warnings to users. Estimating SDC probability of a program is the first and essential step towards designing protection mechanism. Prior work suffers from prediction inaccuracy since the proposed heuristic-based models fail to describe the semantic of fault propagation. We propose a novel approach SLOGAN which transfers the prediction of SDC probability into a graph regression task. A program is represented in the form of dynamic dependence graph. To capture the rich semantic of fault propagation, we apply structured graph attention network, which includes node-level, graph-level and layer-level self-attention. With the learned attention coefficients from node-level, graph-level, and layer-level self-attention, the importance of edges, nodes, and layers to the fault propagation can be fully considered. We generate the graph embedding by weighted aggregation of the embeddings of nodes and compute the SDC probability by the regression model. The experiment shows that SLOGAN achieves higher SDC accuracy than state-of-the-art methods with a low time cost.
Measurement report: Cloud condensation nuclei activity and its variation with organic oxidation level and volatility observed during an aerosol life cycle intensive operational period (ALC-IOP)

Abstract. Cloud condensation nuclei (CCN) spectrum and the CCN activated fraction of size-resolved aerosols (SR-CCN) were measured at a rural site on Long Island during the Department of Energy (DOE) aerosol life cycle intensive operational period (ALC-IOP) from 15 July to 15 August 2011. During the last week of the ALC-IOP, the dependence of the activated fraction on aerosol volatility was characterized by sampling downstream of a thermodenuder (TD) operated at temperatures up to 100 ∘C. Here we present aerosol properties, including aerosol total number concentration, CCN spectrum, and the CCN hygroscopicity, for air masses of representative origins during the ALC-IOP. The hygroscopicity of organic species in the aerosol is derived from CCN hygroscopicity and chemical composition. The dependence of organic hygroscopicity on the organic oxidation level (e.g., atomic O:C ratio) agrees well with theoretical predictions and results from previous laboratory and field studies. The derived κorg and O:C ratio first increase as TD temperature increases from 20 ∘C (i.e., ambient temperature) to 50 or 75 ∘C and then decrease as TD temperature further increases to 100 ∘C. The initial increases of O:C and κorg with TD temperature below 50 ∘C are likely due to evaporation of more volatile organics with relatively lower O:C and hygroscopicity such as primary organic aerosol. At the high TD temperatures, the decreases of O:C and κorg indicate that evaporated organics were more oxygenated and had lower molecular weights. These trends are different from previous laboratory experiments and field observations, which reported that organic O:C increased monotonically with increasing TD temperature, whereas κorg decreased with the TD temperature. One possible reason is that previous studies were either focused on laboratory-generated secondary organic aerosol (SOA) or based on field observations at locations more dominated by SOA.
Survey of Wintering Eurasian woodcock in Western Europe

The Eurasian woodcock ( Scolopax rusticola ) is a mostly migratory wader (Charadriiformes) that is broadly distributed across the Palearctic. This species winters in or migrates through all European countries and is an important quarry species in many of them. Sustainable management of the species requires information regarding abundance and demographic parameters to be collected regularly. This is a complex task given that different phases of its annual life cycle occur in different countries and, due to the species’ secretive behavior, Eurasian woodcock populations cannot be prop-erly evaluated by common bird-census techniques. In Europe, woodcock hunters from different countries have joined in the Federation of Western Palearctic Woodcock Associations (FANBPO), collecting data on hunting activity that can be used to annually evaluate relative abundance and demographic parameters. To investigate variation in Eurasian woodcock relative abundance during and between hunting seasons, we fitted generalized additive mixed models (GAMMs) to data collected in France, Spain, and Portugal (Franco-Iberian region; 2006–2007 to 2015–2016) to analyze the variation in the number of different Eurasian woodcock seen per hunting trip. For these countries and for Switzerland, Italy, Ireland, and Wales, we also analyzed demographic parameters (the ratios of female:male and juvenile:adult) from bagged birds. In the Franco-Iberian region the relative abundance during the autumn-winter period increased from September to the beginning of December, and remained high thereafter with a slight decrease until the end of February; in the last 10 years, relative abundance has remained stable during autumn migration and winter. The sex ratio remained stable in the Swiss-Franco-Iberian and Swiss-Italian regions, but the former had a higher proportion of females. The age ratio varied among hunting seasons and regions. This research is an example of the effective use of data collected through citizen science that aims to maintain a favorable conservation status of the Eurasian woodcock while allowing a rational use of its populations via sustainable and controlled hunting.