Miracle-dz/UniFAR-FTUs huggingface dataset:
Multiphasic profiles for voltage-dependent K+ channels: Reanalysis of data of MacKinnon and coworkers

In a study of the role that voltage-dependent K+ channels may have in the mechanosensation of living cells (Schmidt et al. Proc Soc Natl Acad Sci USA 109: 10352-10357. 2012), the data were as conventionally done fitted by a Boltzmann function. However, as also found for other data for ion channels, this interpretation must be rejected in favor of a multiphasic profile, a series of straight lines separated by discontinuous transitions, quite often in the form of noncontiguities (jumps). The data points in the present study are often very unevenly distributed around the curvilinear profiles. Thus, for 43 of the 75 profiles, the probability is less than 5% that the uneven distribution is due to chance, for 26 the probability is less than 1%, and for 12 the probability is less than 0.1%, giving a vanishingly low overall probability for all profiles. Especially at low voltages, the differences between the fits to curvilinear and multiphasic profiles may be huge. In the multiphasic profiles, adjacent lines are quite often parallel or nearly so, in which case the transitions are, necessarily, in the form of jumps. The lines in the multiphasic profiles appear to be perfectly straight, with no indication of any curvilinearity. The r values are for the most part high, quite often exceedingly high. In addition to activation of ion channels, a wide variety of biological as well as non-biological processes and phenomena involving binding, pH, folding/unfolding and effect of chain length can be well represented by multiphasic profiles (Nissen 2015a,b, 2016. Posted on arXiv.org with Paper ID arXiv: 1511.06601, 1512.02561 and 1603.05144). Introduction
Investigating the basis of memory-based effects on common ground

ABSTRACT Much previous research has investigated the effect of domain-general memory processes on production and comprehension in conversation. In this paper, we present a paradigm in which common ground targets are kept consistent between a participant and two different speakers, and demonstrate a speaker effect that draws participants’ attention away from the common ground target in Experiment 1. Further, we hypothesise that one important factor that promotes speaker identity as a cue for memory processes is that speakers are in conversational partners’ shared attention at the memory coding phase. In Experiments 2 and 3, we demonstrate a non-speaker cue can give rise to a memory-based interference effect when the relevant contextual information is in shared attention but not when it is not. Our results provide an important insight into the interplay of domain-general memory mechanisms and domain specific biases for shared attention.
Effectiveness of two biopesticides against the invasive tomato pest Tuta absoluta

Tuta absoluta (Meyrick) (Lepidoptera: Gelechiidae) is among the most devastating pests worldwide of solanaceous plants, particularly of tomato (Solanum lycopersicum L.). Since its recent introduction into sub‐Saharan Africa, it has become an additional widespread tomato pest throughout the region. When no control measures are taken, yield losses caused by T. absoluta larvae can reach 100%. Chemical control remains the primary management option despite its many adverse effects and increasing inefficiency due to the species’ endophytic habits and ability to develop insecticide resistance. Safer and more effective alternatives are therefore urgently required. Here, we investigated the effectiveness of two bioinsecticides compared to that of a widely used deltamethrin‐based synthetic insecticide, in preventing damage caused by T. absoluta larvae to tomato leaves and fruits, thereby affecting tomato yield. A field trial was conducted in 2018 and 2019 in northwestern Senegal using a randomized complete block design. Damage caused by T. absoluta affected approximately 65% of total leaf area and 3–24% of the fruits. Damage to the leaves caused by other insect species or other factors was less significant. At the dose applied, the chemical insecticide did not significantly reduce the surface area of leaflets affected by T. absoluta or other causal agents, the number of T. absoluta mines on the leaflets, or the proportion of fruits damaged. In contrast, the azadirachtin and Bacillus thuringiensis (Bt) formulations rapidly and significantly reduced damage to both leaves and fruits. The proportion of fruits damaged was reduced by a factor two and the total tomato yield was improved, particularly when the Bt formulation was used. In addition to their effectiveness in reducing damage caused by T. absoluta larvae to tomato leaves and fruit, and increasing the yield of marketable fruits, the viability of these organic alternatives was shown. The scope of our results is discussed in the context of T. absoluta control, in particular in integrated pest management programmes for tomato crops.
Sustainable Mobility Policy Analysis Using Hybrid Choice Models: Is It the Right Choice?

In recent years, sustainable mobility policy analysis has used Hybrid Choice Models (HCM) by incorporating latent variables in the mode choice models. However, the impact on policy analysis outcomes has not yet been determined with certainty. This paper aims to measure the effect of HCM on sustainable mobility policy analysis compared to traditional models without latent variables. To this end, we performed mode choice research in the city of Santander, Spain. We identified two latent variables—Safety and Comfort—and incorporated them as explanatory variables in the HCM. Later, we conducted a sensitivity study for sustainable mobility policy analysis by simulating different policy scenarios. We found that the HCM amplified the impact of sustainable mobility policies on the modal shares, and provided an excessive reaction in the individuals’ travel behavior. Thus, the HCM overrated the impact of sustainable mobility policies on the modal switch. Likewise, for all of the mode choice models, policies that promoted public transportation were more effective in increasing bus modal shares than those that penalized private vehicles. In short, we concluded that sustainable mobility policy analysis should use HCM prudently, and should not set them as the best models beforehand.
Organizational Learning for Environmental Sustainability: Internalizing Lifecycle Management

Implementing a substantial environmental strategy that addresses all phases of the product lifecycle is a complex and demanding challenge that most organizations fail to convincingly overcome. Based on a case study of five frontrunner companies located in Italy and Norway, this study explores the factors that promote, or hinder, the learning process underlying the implementation of substantial measures for lifecycle management and how this can contribute to further internalizing environmental sustainability throughout the organization. The article contributes to the literature on organizational learning and environmental sustainability by showing, from a dynamic perspective, the enablers of organizational learning required for internalizing lifecycle management in organizations. A new framework for environmental sustainability based on the 4Is (intuiting, interpreting, integrating, and institutionalizing) organizational learning model is put forward in line with the concept of lifecycle management. Managerial implications are also discussed.
Risk Factors Associated with End-Stage Renal Disease in Type 2 Diabetes Mellitus Patients

Diabetes Mellitus is a chronic disease and has various complications, including diabetic nephropathy. This complaint is found in 20-40% of diabetes patients and a primary cause of end-stage renal disease. Identifying risk factors has an important role in the implementation of various health promotion and disease prevention activities. This research aims to know the risk factors which related to end-stage renal disease. This is an analytic descriptive study with a case control approach. The study involves 23 people in the test group and 46 in the control group. Bivariat analysis showed risk factors for end-stage renal disease are duration of DM (p-value:0.028), diet pattern (p-value: 0.000; OR: 13.5), hypertension (p-value: 0.036; OR: 2.9), smoking (p-value: 0.027; OR: 3.3), alcohol consumption (p-value: 0.034; OR: 0.3). While sex (p-value: 0.222), history of renal disease in the family (p-value: 0.09), activities (p-value: 0.149/0.457), dyslipidemia (p-value: 0.561) and HbA1c (p-value: 0.246) are not risk factors of end-stage renal disease. The risk factors correlated with end-stage renal disease is duration of DM suffered, smoking habit, drinking alcohol, diet pattern, hypertension. It is recommended that nurses develop a nursing care standardization focused on preventive effort to minimize complication, especially end-stage renal disease.
Insightful behaviour in arthropods?

Arthropod behaviour is usually explained through ‘hard-wired’ motor routines and learning abilities that have been favoured by natural selection. We describe observations in which two arthropods solved rare and perhaps completely novel problems, and consider four possible explanations for their behaviours: (i) the behaviour was a pre-programmed motor routine evolved to solve this particular problem, or evolved for other functions but pre-programmed to be recruited for this function under certain conditions; (ii) it was learned previously; (iii) it resulted by chance; or (iv) it was the result of insightful behaviour. Pre-programmed solutions can be favoured by natural selection if they provide solutions to common or crucial problems. Given the apparent rarity of the problems that these animals solved, the solutions they employed are unlikely to represent innate behaviour. Learning and random chance seem unlikely, although we cannot rule them out completely. Possibly these animals employed some degree of insight.
Enhancing consumers’ self-reported loyalty intentions in Islamic Banks: The relationship between service quality and the mediating role of customer satisfaction

Abstract The main objective of this paper is to investigate how service quality and customer satisfaction are correlated to self-reported loyalty intentions in Islamic banks. The paper presents primary data collected by self-administered questionnaires involving a sample of 655 respondents from all local Islamic Banks in Jordan. The results show that compliance, tangibility, responsiveness, assurance, and empathy positively linked to self-reported loyalty intentions, with compliance and assurance appearing as the greatest correlation with self-reported loyalty intentions compared to other service quality dimensions. Islamic banks should focus on continuous improvement of service quality due to the direct correlation with customer satisfaction and loyalty. It is important for Islamic banks to review and endorse all policies and procedures to ensure that their documents and investments are undertaken in line with the requirements of Islamic law. Managers should pay special attention to the service quality provided by their employees and develop their skill set through training and education programmes based on Islamic principles. As the first study of its kind in Jordan, the paper’s contribution stems from filling the research gap in examining the relationship between the various service quality dimensions and self-reported loyalty intentions in Islamic banks using the CARTER model.
Estimation of the Climate Change Impact on the Hydrological Balance in Basins of South-Central Chile

In this study, the SWAT (Soil Water Assessment Tool) hydrological model is implemented to determine the effect of climate change on various hydrological components in two basins located in the foothills of the Andes: the Quino and Muco river basins. The water cycle is analyzed by comparing the model results to climatic data observed in the past (1982–2016) to understand its trend behaviors. Then, the variations and geographical distribution of the components of the hydrological cycle were analyzed using the Representative Concentration Pathway (RCP)8.5 climate scenario to model two periods considering the immediate future (2020–2049) and intermediate future (2050–2079). In this way, in the study area, it is predicted that yearly average temperatures will increase up to 1.7 °C and that annual average precipitation will decrease up to 210 mm for the intermediate future. Obtained results show that the analyzed parameters presented the same trend behavior for both periods of time; however, a greater impact can be expected in the intermediate future. According to the spatial distribution, the impact worsens for all the parameters as the elevation increases in both basins. The model depicted that yearly average evapotranspiration would increase around 5.26% and 5.81% for Quino and Muco basins, respectively, due to the large increase in temperature. This may cause, when combined with the precipitation lessening, a decrease around 9.52% and 9.73% of percolation, 2.38% and 1.76% of surface flow, and 7.44% and 8.14% of groundwater for Quino and Muco basins, respectively, with a consequent decrease of the water yield in 5.25% and 4.98% in the aforementioned watersheds, respectively.
Elucidating the Influence of the d-Band Center on the Synthesis of Isobutanol

As the search for carbon-efficient synthesis pathways for green alternatives to fossil fuels continues, an expanding class of catalysts have been developed for the upgrading of lower alcohols. Understanding of the acid base functionalities has greatly influenced the search for new materials, but the influence of the metal used in catalysts cannot be explained in a broader sense. We address this herein and correlate our findings with the most fundamental understanding of chemistry to date by applying it to d-band theory as part of an experimental investigation. The commercial catalysts of Pt, Rh, Ru, Cu, Pd, and Ir on carbon as a support have been characterized by means of SEM, EDX-mapping, STEM, XRD, N2-physisorption, and H2-chemisorption. Their catalytic activity has been established by means of c-methylation of ethanol with methanol. For all catalysts, the TOF with respect to i-butanol was examined. The Pt/C reached the highest TOF with a selectivity towards i-butanol of 89%. The trend for the TOFs could be well correlated with the d-band centers of the metal, which formed a volcano curve. Therefore, this study is another step towards the rationalization of catalyst design for the upgrading of alcohols into carbon-neutral fuels or chemical feedstock.
The Antecedents and Consequences of Local Product-Ethnicity Perception—A Study of an Asian Advanced Emerging Market

Although local product ethnicity (local PE) can serve as a key factor in explaining home country biases in local product superiority, this construct has been ignored since it was introduced. To address this limitation, this article proposes a four-phase research model (identifying consumer characteristics, constructing product category schema, categorizing local PE, and evaluating local vs. foreign products) to examine the antecedents and consequences of local PE in an Asian advanced emerging market, which is argued to be a more appropriate context (e.g., more evenly distributed local PE and nonlocal PE categories and coexistence of local and Western product superiority) than developed countries or less-developed emerging markets for this study. Regarding antecedents, the authors identify factors related to consumers’ experiences, information searching, and cognitive bases that can affect their construction of structured knowledge (schemas) about local products within particular categories. Specifically, local embeddedness of product categories is introduced to capture consumer knowledge about strong connotations stereotypically linking the local country to particular categories. As for consequences, the authors compare consumer evaluations of local versus developed-country products/services between local PE and nonlocal PE categories. Four surveys were conducted to empirically examine the model of local PE. The results support the hypotheses.
Do Growth Spillovers Matter?

Accepted: 31 January 2021 Abstract Although the Yogyakarta Special Region and Central Java are two independent provinces with different regulations, these economies were integrated as a unity that interacts with each other, so this study examined whether the growth spillovers between regencies/cities occurred in these provinces. The data included economic growth, education, working-age population, and asphalted road published by the Central Bureau of Statistics for 2001-2018. This study used a regression analysis based on the Dynamic Ordinary Least Square (DOLS) model. The results showed that there were growth spillovers. The economic growth of a regency/city was positively influenced by economic growth in its surrounding regions. A particular regency/city obtained benefit from economic growth occurred in its surrounding. Meanwhile, an increase in the working-age population and the asphalted road positively affects economic growth. However, the increase in education did not affect economic growth. Therefore, the local government needs to improve connectivity between regions by building road networks and enhancing intergovernmental cooperation.
THE MULTIPLE MEDIATION ROLES OF TRUST AND SATISFACTION IN THE EFFECT OF PERCEIVED CORPORATE SOCIAL RESPONSIBILITY ON LOYALTY

Purpose – This study aims at investigating the effect of corporate social responsibility perceptions of local people living in Diyarbakır on bank loyalty in terms of banking services and the mediator roles of trust and satisfaction in this effect. Research methodology – Cronbach’s Alpha coefficients, reliability, convergent and discriminant validity and multicollinearity were examined before testing the hypotheses of the research. The validity of the measurement model for the variables that are included in the model was examined by the confirmatory factor analysis. Partial least squares path modelling was used to analyze the research model and hypotheses, and multiple mediation analysis was used to test the mediation effects. The collected data were analyzed by the software SPSS 22.0 and SmartPLS 3.3. 0. Findings – The research results exposed that the corporate social responsibility perceptions of bank customers have significant and positive effects on bank loyalty. Furthermore, satisfaction has had partial mediation effects on the relationship between CSR perception and loyalty. Research limitations – The population covers individuals with regular wage or salary who live in Diyarbakır. The survey was conducted between October 1 and December 1, 2019, with convenience sampling technique and 400 questionnaires were collected. Practical implications – When conducting CSR activities, businesses should emphasize that trust and satisfaction have an essential effect as well as loyalty. Originality/Value – This study investigated the simultaneous multiple mediator effects of trust and satisfaction in the relationship between CSR and loyalty.
The Flexible Care Model: Transformative Practices for University Counseling Centers

ABSTRACT College and university counseling centers have maintained core practices of advanced scheduling, thorough psychosocial assessment before treatment, and traditional 50-minute psychotherapy sessions since their inception in the mid-late 1900s. This approach has become challenged in the current university mental health landscape, which has seen a significant increase in demand for psychological treatment on campus, interest in rapid access to care, and long wait times for services. Drawing on principles from common factors research, multicultural psychology, and urgent care medicine, the Flexible Care Model embraces an alternative approach, with core practices that include same day access, variable session lengths, goal-focused counseling, and customizable follow-up plans. This article is an introduction to the model.
Exploring residents' support for integrated casino resort development: a new gaming destination in Vietnam

ABSTRACT Integrated casino resorts have presented themselves as key strategic gaming destinations in many countries. Several countries including Vietnam have developed integrated casino resorts to attract tourists and to stay competitive. To achieve sustainable success, residents’ perceptions should be considered in strategic planning and execution of gaming destinations. This study explores residents’ perceptions of integrated casino resorts and how these perceptions are extended for identifying conditions influencing residents’ support in gaming destination development. A newly developed gaming destination, the Grand Ho Tram Resort and Casino in South Vietnam, was chosen as the research site. Semi-structured in-depth face-to-face interviews were conducted for data collection. NVivo was preliminarily used for thematic analysis and content analysis was further undertaken for analysing and interpreting the data. Favourable social and economic returns were found as necessary conditions to secure residents’ support. Efforts in improving cultural and environmental well-being of residents should be promoted to elicit residents’ support for sustained gaming destination development. Given residents’ perceptive insights into impacts of significance to them, the findings will be beneficial for strategic planning and execution of gaming destinations and future tourism development.
Healthcare workers’ knowledge, risk perception, safety-relevant practices, and work situation during the COVID-19 pandemic: A quantitative survey from Switzerland

Objective: To determine the impact of the COVID-19 pandemic on healthcare workers and healthcare students in higher education and to assess their clinical knowledge, media use, risk perception, perception of governmental measures, and adherence to preventive guidelines to provide policymakers with field-based evidence. Methods: This cross-sectional quantitative survey was conducted by two-stage cluster sampling among Swiss healthcare workers, who performed patient care during the first pandemic wave, and who also pursued an education at a university of applied sciences at the same time (a Bachelor’s or Master’s degree in nursing or an executive degree in healthcare). 75 individuals participated between 5th May and 1st June 2020. Their data was analyzed by bivariate hypothesis testing and multiple logistic regression. Results: Considerable levels of task-related and emotional stress were prevalent, accompanied by a large proportion of respondents who did not have sufficient protective materials or necessary decisions in place to effectively protect themselves or others from infection with COVID-19. Knowledge was considerably limited, especially regarding the efficacy of standard hygiene as a preventive measure. The preparation of the government and the healthcare sector was perceived as insufficient. Conclusions: Comprehensive management of infodemic challenges and foresighted development of education, human resources, clinical processes, and protective materials are highly recommended.