Miracle-dz/UniFAR-FTUs huggingface dataset:
Effect of Zinc Oxide Nanoparticles on The Spleen of Adult Male Albino Rat and The Possible Protective Role of Selenium: Microanatomical and Biochemical Study.

: Thirty five adult male albino rats were used in this study. They were divided into 7 groups: Group I (Control), Group II (low dose Zno NPs group) , Group III (medium dose Zno NPs group) , Group IV (high dose Zno NPs group) , Group V (low dose Zno NPs-selenite group), Group VI (medium dose Zno NPs-selenite group), Group VII (high dose Zno NPs-selenite group): tissue of the spleen was examined histopathologically and immunohistochemical , Determination of blood cells count (number of white blood cells (WBCs), red blood corpuscles (RBCs) and platelets. Also tissue level of Hydrogen peroxide (H2O2) and paraoxonase-1(pon-1): for detection of oxidative stress estimated for all groups, PCR detection of apoptosis inducing factor (AIF), apoptotic protease activating factor-1 and caspases 3 and Zinc level in the spleen. Results of the present study showed that, compared to controls: orally intake of Zinc oxide nanoparticles (Zno NPs) cause marked changes in spleen tissues as thickening of capsule, thickening of trabeculae , destruction of white pulp and red pulp expansion especially in groups receiving zinc oxide nanoparticles only and these changes markedly decreased on groups receiving selenium as protection.
Diabetes Self-Management: Self-reported recommendations and patterns in a large population

OBJECTIVE Diabetes self-management is the cornerstone of overall diabetes management. Yet many questions concerning self-management remain unanswered. The current study was designed to examine several questions about diabetes self-management: 1) What do individuals report being told to do? 2) What are their self-reported levels and patterns of self-care? 3) Are there differences on self-reported self-management recommendations and levels across various subgroups? RESEARCH DESIGN AND METHODS Mailed surveys were returned by 2,056 individuals (73.4% response rate). Of the total, 13.8% had IDDM and the remainder had NIDDM, with 65% of the NIDDM group using insulin. RESULTS The levels and patterns of self-management were consistent with those found in previous studies, i.e., individuals most regularly followed their prescribed medication regimen and least regularly followed recommendations for lifestyle changes of diet and exercise. There were significant differences on reported self-management recommendations across different subgroups. Comparisons on level of self-management across diabetes type revealed significant differences for diet and glucose testing. Differences were also found on self-management levels for a number of individual characteristics, including age, working status, and type of insurance, along with knowledge of the Diabetes Control and Complications Trial findings. CONCLUSIONS These findings provide important information on perceived self-management recommendations and the specific self-management levels and patterns in individuals with diabetes. The current findings may help health professionals better understand the levels and correlates of diabetes self-management and direct future research.
Diabetes self-management : strategies to support patients and health care professionals

Education is an essential part of diabetes care. However, in the Netherlands, no education programme was available for everyone at any time and adaptive to user’s specific needs. The aim of this article is to describe the structured development and final content of a type 2 diabetes web-based education programme. A web-based education programme – the Diabetes Interactive Education Programme (DIEP) – was developed using intervention mapping and involved collaboration between programme planners, Dutch diabetes organizations and potential users (patients and health care professionals). DIEP incorporates information, multimedia and tools to support self-reflection, goal setting, problem solving and active patient participation. www.diep. info consists of seven chapters with basic and additional information, a dictionary, self-management checklists and a workbook for goal setting and preparation for consultations. The information included is mostly spoken text supported by headlines, images, video and patient experiences. Adoption, implementation and evaluation plans have been made. Outcomes of the process and effect evaluation will be reported in the future. DIEP is a unique education programme, based on theory and planned development, which is supported by diabetes organizations. By using multimedia and incorporating different functionalities, DIEP attempts to meet the current practice requirements. DIEP aims to meet the needs of multiple, specific patient groups in the future, and has already been adapted for use in different countries (e.g. Belgium). Development of www.diep. info ⏐23
Understanding Momentum and Reversal

Stock momentum, long-term reversal, and other past return characteristics that predict future returns also predict future realized betas, suggesting these characteristics capture time-varying risk compensation. We formalize this argument with a conditional factor pricing model. Using instrumented principal components analysis, we estimate latent factors with time-varying factor loadings that depend on observable firm characteristics. We show that factor loadings vary significantly over time, even at short horizons over which the momentum phenomenon operates (one year), and that this variation captures reliable conditional risk premia missed by other factor models commonly used in the literature. Our estimates of conditional risk exposure can ex- plain a sizeable fraction of momentum and long-term reversal returns and can be used to generate even stronger return predictions.
Relations between abundance characteristics and rotation velocity for star-forming MaNGA galaxies

I.A. Z. acknowledge support within the framework of Sonderforschungsbereich (SFB 881) on >The Milky Way System> (especially subproject A05), which is funded by the German Research Foundation (DFG). L.S. P. and I.A. Z. thank for their hospitality of the Astronomisches Rechen-Institut at Heidelberg University, where part of this investigation was carried out. I.A. Z. acknowledges the support of the Volkswagen Foundation under the Trilateral Partnerships grant No. 90411. I.A. Z. acknowledges the support by the Ukrainian National Grid project (especially subproject 400Kt) of the NAS of Ukraine. J.M. V acknowledges financial support from projects AYA2017-79724-C4-4-P, of the Spanish PNAYA, and Junta de Andalucia Excellence PEX2011-FQM705. This work was partly funded by the subsidy allocated to Kazan Federal University for the state assignment in the sphere of scientific activities (L.S.P.).
vancomycin-resistant enterococcal infections : epidemiology , clinical manifestations , and optimal management

License. The full terms of the License are available at http://creativecommons.org/licenses/by-nc/3.0/. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. Permissions beyond the scope of the License are administered by Dove Medical Press Limited. Information on how to request permission may be found at: http://www.dovepress. com/permissions.php Infection and Drug Resistance 2015:8 217–230 Infection and Drug Resistance Dovepress
Mid-regional pro-atrial natriuretic peptide and pro-adrenomedullin testing for the diagnostic and prognostic evaluation of patients with acute dyspnoea.

AIMS The aim of this study was to assess diagnostic and prognostic value of mid-regional pro-atrial natriuretic peptide (MR-proANP) and adrenomedullin (MR-proADM) for the evaluation of patients presenting to the emergency department with acute dyspnoea. METHODS AND RESULTS A total of 560 patients from the pro-B type natriuretic peptide Investigation of Dyspnoea in the Emergency Department were evaluated; 180 had acutely decompensated heart failure (ADHF). Concentrations of amino-terminal pro-B type natriuretic peptide (NT-proBNP), MR-proADM, and MR-proANP were measured, and patients were followed to 4 years for survival. Logistic regression evaluated utility of MR-proANP in ADHF diagnosis. Area under the curve (AUC), multivariate Cox regression, net reclassification improvement, and Kaplan-Meier survival analyses were used for mortality analyses. Mid-regional pro-atrial natriuretic peptide was higher in patients with ADHF (median 329 vs. 58 pmol/L; P < 0.001), and remained an independent predictor of HF diagnosis even when NT-proBNP was included as a covariate (odds ratio = 4.34, 95% CI = 2.11-8.92; P < 0.001). In time-dependent analyses, MR-proADM had the highest AUC for death during the first year; after 1 year, MR-proANP and NT-proBNP had a higher AUC. Both mid-regional peptides were independently prognostic and reclassified risk at 1 year [MR-proANP, hazard ratio (HR) = 2.99, MR-proADM, HR = 2.70; both P < 0.001] and at 4 years (MR-proANP, HR = 3.12, P < 0.001; MR-proADM, HR = 1.51, P = 0.03) and in Kaplan-Meier curves both mid-regional peptides were associated with death out to 4 years, individually or in a multimarker strategy. CONCLUSION Among patients with acute dyspnoea, MR-proANP is accurate for diagnosis of ADHF, while both MR-proANP and MR-proADM are independently prognostic to 4 years of the follow-up.
Soil moisture retrieval using L-band time-series SAR data from the SMAPVEX12 experiment

The algorithms for retrieving soil moisture contents within the top 5 cm of the soil using the L-band multipolarized radar data from the future Soil Moisture Active and Passive (SMAP) mission were applied to the data sets obtained by the recent aircraft field campaign in Winnipeg Canada in 2012 (SMAPVEX12), and the algorithm performance was evaluated. Two algorithms are: the time-series inversion of radar scattering forward models "data-cubes" and the change detection method. The SMAPVEX12 data sets include airborne synthetic aperture radar (SAR) data and ground-based measurements of soil and vegetation. These data were collected over fields with diverse crops and a wide range of moisture and vegetation conditions. In general, volumetric soil moisture and backscattering coefficients showed a positive relationship and the vegetation effects were significant for corn and beans. Assessed over all available fields of corn, beans, pasture, and wheat, the datacube time-series inversion resulted in a retrieval rmse of 0.050 to 0.090 cm3/cm3, and correlations of 0.5 to 0.9. Compared with the change detection approach, the data-cube inversion performed better in the presence of significant vegetation growth.
Evaluation of Retinal Nerve Fiber Layer Thickness with Optical Coherence Tomography in Type 1 Diabetes Mellitus Patients

ABS TRACT Ob jec ti ve: To eva lu a te re ti nal ner ve fi ber la yer (RNFL) thick ness chan ges of type 1 dia be tes mel li tus (DM) pa ti ents with and wit ho ut di a be tic re ti no pathy (DR). Ma te ri al and Met hods: One hun dred-eigh te en pa ti ents with type 1 DM and 49 age-matc hed con trol sub jects we re en rol led in the study. Ni net y e ight of 118 di a be tic pa ti ents with DR we re as sig ned as gro up 1 and the re ma i ning 20 pa ti ents wit ho ut DR we re la be led as gro up 20 (n= 98). The RNFL thick ness of all subjects we re me a su red using op ti cal co he ren ce to mog raphy (OCT). Re sults: The study inc lu ded 118 type 1 DM pa ti ents with a me an age of 18.77±8.80 ye ars. The me an age of 49 sub jects in the control gro up was 18.71 ± 5.72 (ran ge 7-40) ye ars.The me an RNFL thick ness was 103.79 ± 6.45 μm in the con trol gro up, 100.00 ± 11.93 μm in gro up 1 and 85.59 ± 19.81 μm in gro up 2. The dec re a se in gro up 2 was fo und sta tis ti cally sig ni fi cant (p< 0.001). The me an RNFL thick ness in the su pe ri or, na sal, in fe ri or and tem po ral qu ad rants we re less in gro up 1 com pa red to con trols, ho we ver this da ta was not sta tis ti cally sig ni fi cant (p= 0.274, p= 0.149, p= 0326, p= 0783, res pec ti vely). In gro up 2, the RNFL thick ness re ve a led a sta tis ti cally sig ni fi cant dec re a se in all qu ad rants (p< 0.001) ex cept tem po ral qu ad rant (p= 0.396). The me an du ra ti on of DM was sig ni fi cantly lon ger in gro up 2 (153.80 ± 70.35) com pa red to gro up 1 (60.76 ± 50.41 months) (p< 0.001). However, the re was no cor re la ti on bet we en the RNFL thick ness and the du ra ti on of DM. Conc lu si on: The RNFL thickness of pa ti ents with type 1 DM was fo und less com pa red to con trol sub jects. This was mo re pro mi nent in pa ti ents with es tab lis hed re ti no pathy (gro up 2). The se fin dings sug ges ted that the RNFL thick ness me a su re ment with the aid of OCT may be used as an ad junc ti ve di ag nos tic to ol for early di ag no sis of DR.
Ulam stabilities for nonlinear Volterra-Fredholm delay integrodifferential equations

In the present research paper we derive results about existence and uniqueness of solutions and Ulam--Hyers and Rassias stabilities of nonlinear Volterra--Fredholm delay integrodifferential equations. Pachpatte's inequality and Picard operator theory are the main tools that are used to obtain our main results. We concluded this work with applications of obtained results and few illustrative examples.
Stochastic Surface Growth

Growth phenomena constitute an important field in nonequilibrium statistical mechanics. Kardar, Parisi, and Zhang (KPZ) in 1986 proposed a continuum theory for local stochastic growth predicting scale invariance with universal exponents and limiting distributions. For a special, exactly solvable growth model (polynuclear growth - PNG) on a one-dimensional substrate (1+1 dimensional) we confirm the known scaling exponents and identify for the first time the limiting distributions of height fluctuations for different initial conditions (droplet, flat, stationary). Surprisingly, these so-called Tracy-Widom distributions have been encountered earlier in random matrix theory. The full stationary two-point function of the PNG model is calculated. Its scaling limit is expressed in terms of the solution to a special Rieman-Hilbert problem and determined numerically. By universality this yields a prediction for the stationary two-point function of (1+1)-dimensional KPZ theory. For the PNG droplet we show that the surface fluctuations converge to the so-called Airy process in the sense of joint distributions. Finally we discuss the theory for higher substrate dimensions and provide some Monte-Carlo simulations.
A comparative study of the physicochemical properties and emulsion stability of coconut milk at different maturity stages

Based on chemical analysis, mature coconut (MC) milk had the highest moisture content (p<0.05), followed by immature coconut (IMC) and overlay mature coconut (OMC) milk, respectively. OMC milk had the highest lipid content while IMC milk showed the lowest lipid content (p<0.05). The lowest protein and carbohydrate contents were found in MC milk (p<0.05). Cocosin with MW of 55 kDa was observed as the major protein in all coconut milks; however, the band intensity slightly decreased with increasing maturity stages. Increase in oil droplet size was observed with increasing maturity stages.Therefore, maturity stages have an influence on the chemical compositions, properties and emulsion stability of coconut milk.
Growth , yield and quality responses to gibberellic acid ( GA 3 ) of Wax apple Syzygium samarangense var . Jambu air madu fruits grown under field conditions

A study was carried out to investigate the effects of gibberellic acid (GA3) on the growth and development of the red jambu air madu fruits (Syzygium samarangense). Various horticultural parameters were monitored during two seasons of fruit growth between December, 2008 to December, 2009 with the application of three concentrations of GA3 at 20, 50 and 100 mg/L. It was observed that the application of GA3 at 50 mg/L increased fruit length and diameter. Furthermore, it enhanced faster fruit growth and color development in addition to increasing fruit number, weight and yield. It also decreased premature fruit dropping. However, spraying with 20 mg/L GA3 increased the number of buds and fruit setting and reduced bud dropping before anthesis. With regard to fruit quality, the application of GA3 at 50 mg/L increased total soluble solids (TSS), total sugar, total biomass and total flavonoids content in the fruits by 112, 97, 45 and 92% compared with the control treatment. In addition, anthocyanin content, total phenol and antioxidant activity was higher in GA3 treated fruits. From this study, it can be concluded that spraying with 50 mg/L GA3 once a week results in better yield and quality of jambu madu fruits under field conditions.
Trophic interactions and abiotic forcing in the aquatic ecosystems : a modeling approach

Analyses of the effects of extreme climate periods have been used as a tool to predict ecosystem functioning and processes in a warmer world. The winter half-year 2006/2007 (w06/07) has been extremely warm and was estimated to be a half-amillennium event in central Europe. Here we analyse the consequences of w06/07 for the temperatures, mixing dynamics, phenologies and population developments of algae and daphnids (thereafter w06/07 limnology) in a deep central European lake and investigate to what extent analysis of w06/07 limnology can really be used as a predictive tool regarding future warming. Different approaches were used to put the observations during w06/07 into context: 1) a comparison of w06/07 limnology with long-term data, 2) a comparison of w06/07 limnology with that of the preceding year, and 3) modelling of temperature and mixing dynamics using numerical experiments. These analyses revealed that w06/07 limnology in Lake Constance was indeed very special as the lake did not mix below 60m depth throughout winter. Because of this, anomalies of variables associated strongly with mixing behaviour, e.g. Schmidt stability and a measure for phosphorus upward mixing during winter exceeded several standard deviations the long-term mean of these variables. However, our modelling results suggest that this extreme hydrodynamical behaviour was only partially due to w06/07 meteorology per se, but depended also strongly on the large difference in air temperature to the previous cold winter which resulted in complete mixing and considerable cooling of the water column. Furthermore, modelling results demonstrated that with respect to absolute water temperatures, the model “w06/07” most likely underestimates the increase in water temperature in a warmer world as one warm winter is not sufficient to rise water temperatures in a deep lake up to those expected under a future climate.
Measurement of the ratio of branching fractions $\mathcal{B}(B^0\to K^{*0}\gamma)/\mathcal{B}(B_s^0\to\phi\gamma)$

The ratio of branching fractions of the radiative B decays B0 ->K*0 gamma and Bs0 ->phi gamma has been measured using 0.37 fb-1 of pp collisions at a centre of mass energy of sqrt(s) = 7 TeV, collected by the LHCb experiment. The value obtained is BR(B0 ->K*0 gamma)/BR(Bs0 ->phi gamma) = 1.12 +/- 0.08 ^{+0.06}_{-0.04} ^{+0.09}_{-0.08}, where the first uncertainty is statistical, the second systematic and the third is associated to the ratio of fragmentation fractions fs/fd. Using the world average for BR(B0 ->K*0 gamma) = (4.33 +/- 0.15) x 10^{-5}, the branching fraction BR(Bs0 ->phi gamma) is measured to be (3.9 +/- 0.5) x 10^{-5}, which is the most precise measurement to date.
Development and Analytical Validation of an Enzyme-linked Immunosorbent Assay (ELISA) for the Measurement of Feline Alpha1-proteinase Inhibitor (fa1-PI) in Serum and Feces and the Evaluation of Fecal fa1-PI Concentrations in Cats with Idiopathic Inflammatory Bowel Disease or Gastrointestinal Neoplas

Development and Analytical Validation of an Enzyme-Linked Immunosorbent Assay (ELISA) for the Measurement of Feline Alpha1-Proteinase Inhibitor (fα1-PI) in Serum and Feces and the Evaluation of Fecal fα1-PI Concentrations in Cats with Idiopathic Inflammatory Bowel Disease or Gastrointestinal Neoplasia. (August 2012) Kathrin Fetz Burke, med. vet. , Dr. med. vet. ; University of Veterinary Medicine, Hannover, Germany Chair of Advisory Committee: Dr. Jörg M. Steiner Alpha1-proteinase inhibitor (α1-PI) has been shown to be a useful marker of gastrointestinal protein loss in some species. The objectives of this study were, first, to develop and analytically validate an ELISA for the measurement of α1-PI in feces and serum from cats, and, second, to evaluate fecal α1-PI concentrations in healthy cats and cats with chronic gastrointestinal disease. The lower detection limits of the ELISA were 0.02 g/L for serum and 0.04 μg/g for feces. The observed-to-expected (O/E) ratios for serial dilutions of serum and fecal samples ranged from 100.0 to 129.7% (mean ±SD: 112.2 ±9.9%) and 103.5 to 141.6% (115.6 ±12.8%), respectively. The O/E ratios for samples spiked with seven known concentrations of α1-PI ranged from 82.3 to 107.8% (94.7 ±7.6%) for serum and 78.5 to 148.7% (96.8 ±18.2%) for feces. The coefficients of variation for intra-assay and interassay variability were <7.9% and <12.1% for serum, and 5.3%, 11.8%, and 14.2% and
Plant Science Today

Wild Solanum torvum shows widespread distribution throughout the state of Tripura. In this investigation, diversity analysis of five populations of S. torvum, each represented by single accession, from different geographical locations of Tripura has been carried out for the first time using two types of molecular markers, Simple Sequence Repeats (SSR) and Rapid Amplified Polymorphic DNA (RAPD). SSR markers revealed a high degree of polymorphism (86.38%) in comparison to RAPD primers (79.16%). Polymorphic information content ranged from 0.28 to 0.54 for SSR and 0.16 to 0.41 for RAPD, respectively. UPGMA cluster analyses based on molecular data grouped the genotypes into two different clusters. Our findings suggests that SSR has a high discriminatory power wherein it was observed that the genotype from Jampui hills (STP5) with greater genetic diversity is stabilized in the high altitude of SubHimalayan region of Tripura in the due course of evolution.
Technological Entrepreneurship in China: How Does It Work?

Contents: Foreword Introduction 1. Entrepreneurship of Innovative High-tech Development in China: Two Case Studies Huijiong Wang, Shantong Li and Yan Hong 2. Regional Innovation Systems in China - An Analysis of Industry-Science Linkages in the Bohai Bay Area Ulrike Tagscherer, Henning Kroll and Xin Luo 3. Upgrading Strategies of Electronics Firms within the Regional Innovation System of the Pearl River Delta, Illustrated by the Example of Two Hong Kong Firms Henning Kroll and Daniel Schiller 4. From a University-run Enterprise to a Leading Group of Regional IT Industrial Clusters: In a Perspective of Academia-Government-Industry Triple Helix Chunyan Zhou 5. Solar Photovoltaic Industry Development from the Early 90s to the World Leadership Marco Andreozzi 6. Huawei and Zhengfei Ren: Leadership in a Technology-Innovative Firm Yingying Zhang and Yajun Wu 7. Spreadtrum: Aspiring to be a World Class Chip Company Yan Wan and Shi-Ji Gao 8. A Case Study on Chinese Manufacturing Company's Catch-up Strategy and R&D Talent's Creative Role Identity Management Chaoying Tang and Jiannong Shi 9. Technological Entrepreneurship with Chinese Characteristics: The QQ Robot Case Claudio Petti, Xiaowei Hu and Shujun Zhang
Management in tourism

Jesenko (statistical methods, University of Maribor) and Kiereta (economics, University of Aachen) gather work on less-studied aspects of tourism management. Human resources, the planning process in tourism, and the need for implementation of new media related to holidays and business travel are major subjects discussed here. Environmental protecti