Miracle-dz/UniFAR-FTUs huggingface dataset:
Effects of combined cognitive and physical intervention on enhancing cognition in older adults with and without mild cognitive impairment: A systematic review and meta-analysis

Background Combined cognitive and physical intervention is commonly used as a non-pharmacological therapy to improve cognitive function in older adults, but it is uncertain whether combined intervention can produce stronger cognitive gains than either single cognitive or sham intervention. To address this uncertainty, we performed a systematic review and meta-analysis to evaluate the effects of combined intervention on cognition in older adults with and without mild cognitive impairment (MCI). Methods We systematically searched eight databases for relevant articles published from inception to November 1, 2021. Randomized controlled trials (RCTs) and non-randomized controlled trials (NRCTs) were used to compare the effects of the combined intervention with a single cognitive or sham intervention on cognition in older adults with and without MCI aged ≥ 50 years. We also searched Google Scholar, references of the included articles, and relevant reviews. Two independent reviewers performed the article screening, data extraction, and bias assessment. GRADEpro was used to rate the strength of evidence, and RevMan software was used to perform the meta-analysis. Results Seventeen studies were included in the analysis, comprising eight studies of cognitively healthy older adults and nine studies of older adults with MCI. The meta-analysis showed that the combined intervention significantly improved most cognitive functions and depression (SMD = 0.99, 95% CI 0.54–1.43, p < 0.0001) in older adults compared to the control groups, but the intervention effects varied by cognition domains. However, there was no statistically significant difference in the maintenance between the combined and sham interventions (SMD = 1.34, 95% CI −0.58–3.27, p = 0.17). The subgroup analysis also showed that there was no statistical difference in the combined intervention to improve global cognition, memory, attention, and executive function between cognitive healthy older adults and older adults with MCI. Conclusions Combined intervention improves cognitive functions in older adults with and without MCI, especially in global cognition, memory, and executive function. However, there was no statistical difference in the efficacy of the combined intervention to improve cognition between cognitive healthy older adults and older adults with MCI. Moreover, the maintenance of the combined intervention remains unclear due to the limited follow-up data and high heterogeneity. In the future, more stringent study designs with more follow-ups are needed further to explore the effects of combined intervention in older adults. Systematic review registration https://www.crd. york.ac. uk/PROSPERO/#recordDetails, identifier: CRD42021292490.
Modeling to predict thermal aging for flame-retardant fabrics considering thermal stability under fire exposure

The performance of firefighters’ clothing will deteriorate due to various exposures. Predicting its service life before decommissioning is essential to guide the use and maintenance of the uniform. The aim of this study is to introduce a model to predict the tensile strength of flame-retardant fabrics under fire exposure. The thermal degradation and microstructure of Kevlar/polybenzimidazole and polyimide/Kevlar fabrics were investigated. The decrease of tensile strength was attributed to the chemical changes and the development of microstructure cracks and charring of the fibers. Multiple linear regression (MLR) and artificial neural network (ANN) models were established to predict the tensile strength after thermal aging. The ANN model presented a better prediction result (R2 = 0.88, root mean square error (RMSE) = 96.91) than the MLR method (R2 = 0.76, RMSE = 138.61). The addition of fabric backside temperature (T), glass transition temperature (Tg), and degradation temperature (Td) further increased the R2 (4%) and decreased the RMSE (14.99) of the ANN model, which was recommended as a prediction approach with better accuracy. The findings of this study will contribute to estimating the continuous performance of firefighting clothing.
Estimates of genetic variability, inter character association and path analysis in turmeric over environments

Pooled data of 27 traits, including quantitative and qualitative, from 15 turmeric varieties grown in three locations over two years were used to estimate the genetic parameters of variability and path analysis. High genotypic coefficient of variation (GCV) combined with high phenotypic coefficient of variation (PCV) was observed for collar girth, length of mother rhizome, number of mother rhizomes, weight of mother rhizome, weight of primary rhizome, number of secondary rhizomes, primary rhizome inter-nodal length, bisdemethoxycurcumin (BDMC), demethoxycurcumin (DMC), curcumin (CUR) and yield. High heritability coupled with high genetic advance as per cent mean (GAM) was recorded for plant height, number of shoots, leaf petiole length, leaf length, collar girth, length of mother rhizome, girth of mother rhizome, primary rhizome inter-nodal length, dry recovery, oleoresin, BDMC, DMC and curcumin. Correlation coefficients showed that yield was significantly associated with collar girth, weight of mother rhizome, number of primary rhizomes, weight of primary rhizome and number of secondary rhizomes. Path coefficient analysis at phenotypic level revealed that, positive direct effect was high for length of mother rhizome followed by number of mother rhizomes, weight of primary rhizome and curcumin content. The study confirmed that characters such as weight of mother rhizome, girth of mother rhizome, weight of primary rhizomes, number of primary rhizomes and curcumin content can be relayed upon to form selection criteria in turmeric.
COVID-19 restrictions, pub closures, and crime in Oslo, Norway

ABSTRACT Alcohol consumption and crime are closely linked and there is often more crime near pubs and bars. Few studies have considered the impact of restricting access to pubs or bars on crime, and the present study aims to provide more insight into this by using the restrictions to combat the COVID-19 pandemic as a natural experiment. In Oslo, Norway, alcohol serving was banned twice during 2020, and at other times during the year, restrictions were placed on how late it could be served. In the present paper, these restrictions are analysed, alongside more general COVID-19 restrictions, to assess their association with crime. To identify these, we employ negative binomial regression models of daily crime counts for nine types of crime adjusted for the day of the week, the week of the year, and the year itself. This is in addition to the presence, or absence, of alcohol-related restrictions and more general COVID-19 restrictions. The findings suggest that both, general restrictions and bans on serving alcohol, reduced crime, although not universally across all crime types and times of the day. When pubs are ordered not to sell alcohol after midnight there appears to be an unexpected increase in crime.
Mechanisms of Landslide Destabilization Induced by Glacier‐Retreat on Tungnakvíslarjökull Area, Iceland

The massive worldwide deglaciation leads to more frequent slope instabilities in mountainous terrains. The physical processes leading to such destabilizations are poorly constrained due to little monitoring of dynamic parameters at the local scale. Here we study a very large slow‐moving landslide (∼0.8 km2), on the flank of Tungnakvíslarjökull glacier in Iceland. Based on a combination of remote sensing images, we monitor the landslide and glacier kinematics over 75 years, with a focus over the period 1999–2019 when rapid glacier wastage has been observed. The landslide accelerates from 2 to 45 m/yr in the 6 years following a sudden increase in glacier mass loss. This acceleration coincides with intense quake activity (Mℓ < 2.8), recorded by a regional seismic network. We show that this seismicity is caused by the landslide sliding on a rough surface. The evolution of the quake magnitudes suggests a progressive segmentation of the landslide mass during its acceleration.
A Pilot Study Considering Ecoroofs as Therapeutic Landscapes

The potential for urban open spaces to convey therapeutic benefits is increasingly substantiated. More work is needed to specifically consider how low impact designs to manage stormwater such as ecoroofs perform in this context. Here, we report on a pilot study addressing: (1) factors determining whether a hospital has an ecoroof, and (2) how ecoroofs might convey therapeutic benefits. We utilized a mixed methods approach which encompassed phone interviews of hospital ecoroof managers as well as analysis of national hospital databases. We also conducted a local case study which compared cortisol samples and stress indicators from patients, staff, and caregivers visiting an ecoroof to those waiting indoors at the Oregon Health and Sciences University in Portland OR. Behavioral observations took place at this same location. In 2017, we identified 105 hospitals with ecoroofs in the contiguous United States. Our analysis of a national hospital database found two factors that significantly increased the likelihood of a hospital having an ecoroof: Medicaid discharges per year; and non-profit status. Interviews with practitioners nationally revealed a wide range of motivations but that therapy was a consideration for a majority, but notably not all, of the hospitals surveyed. They similarly noted variation in roof design, maintenance, and programming around horticultural therapy; we highlight some best practices here. Our physiological case study was limited in sample size. Preliminary findings showed that salivary cortisol levels varied by ecoroof visitor type, ranging on average from 0.09 μg/ml for caregivers to 0.30 μg/ml for patients. We did not observe any significant changes in visitor cortisol. This could be explained by low replication or the short treatment duration. Alternatively, these pilot data may indicate a gap in horticultural therapy theory vs. practice. Behavioral observations demonstrated a wide array of different uses of the ecoroof space such as cell phone use and passing by. Though preliminary, our findings suggest that therapeutic effects may vary by user type and activity and depend on roof design and goals. This study offers both information on the therapeutic potential of hospital ecoroofs as well as lessons learned regarding different approaches to researching this somewhat new topic.
Acute effects of mixed circuit training on hemodynamic and cardiac autonomic control in chronic hemiparetic stroke patients: A randomized controlled crossover trial

Objectives: To investigate whether a single bout of mixed circuit training (MCT) can elicit acute blood pressure (BP) reduction in chronic hemiparetic stroke patients, a phenomenon also known as post-exercise hypotension (PEH). Methods: Seven participants (58 ± 12 years) performed a non-exercise control session (CTL) and a single bout of MCT on separate days and in a randomized counterbalanced order. The MCT included 10 exercises with 3 sets of 15-repetition maximum per exercise, with each set interspersed with 45 s of walking. Systolic (SBP) and diastolic (DBP) blood pressure, mean arterial pressure (MAP), cardiac output (Q), systemic vascular resistance (SVR), baroreflex sensitivity (BRS), and heart rate variability (HRV) were assessed 10 min before and 40 min after CTL and MCT. BP and HRV were also measured during an ambulatory 24-h recovery period. Results: Compared to CTL, SBP (∆-22%), DBP (∆-28%), SVR (∆-43%), BRS (∆-63%), and parasympathetic activity (HF; high-frequency component: ∆-63%) were reduced during 40 min post-MCT (p < 0.05), while Q (∆35%), sympathetic activity (LF; low-frequency component: ∆139%) and sympathovagal balance (LF:HF ratio: ∆145%) were higher (p < 0.001). In the first 10 h of ambulatory assessment, SBP (∆-7%), MAP (∆-6%), and HF (∆-26%) remained lowered, and LF (∆11%) and LF:HF ratio (∆13%) remained elevated post-MCT vs. CTL (p < 0.05). Conclusion: A single bout of MCT elicited prolonged PEH in chronic hemiparetic stroke patients. This occurred concurrently with increased sympathovagal balance and lowered SVR, suggesting vasodilation capacity is a major determinant of PEH in these patients. This clinical trial was registered in the Brazilian Clinical Trials Registry (RBR-5dn5zd), available at https://ensaiosclinicos.gov. br/rg/RBR-5dn5zd. Clinical Trial Registration: https://ensaiosclinicos.gov. br/rg/RBR-5dn5zd, identifier RBR-5dn5zd
INCIDENCE OF MYCOTOXINS IN MOULDY SMOKED DRIED FISH AND MEAT (KUNDI) MARKETED IN SOUTHWESTERN NIGERIA

The mycotoxicological safety of 85 mouldy dried fish (n=40) and meat (n=45) samples purchased from Ijebu-ode, Ogun State and Aleshinloye, Ibadan, Oyo State markets both in South Western part of Nigeria respectively, was assessed due to heavy consumption of these animal protein sources by many low-income families in Nigeria. The presence of aflatoxigenic moulds and levels of aflatoxins in the samples were determined by the dilution plating technique and high performance thin-layer chromatographic method. The predominant fungal species isolated from the samples was Aspergillus niger-clade (49.65%); other species isolated include Aspergillus section Flavi (36.83%) and (13.52%). All samples analysed for mycotoxin presence were contaminated with aflatoxin B1. Aflatoxin B2, G1 and G2 were below detectable limits. About 13% of the samples had aflatoxin B1 concentration higher than the maximum acceptable level (10 ng/g). Results imply that the consumption of mouldy dried meat can result in serious public health hazard and hence there is need for advocacy programs to enlighten the populace on proper processing and storage of meat products.
Determining Experience Quality on Customers' Perceived Value, Satisfaction and Loyalty

It is essential in the hospitality and tourism industries to meet the gastronomic expectations of travelers. The purpose of this study is to investigate the impact of customer perceived value on customer loyalty and satisfaction, experience quality on customer perceived value and loyalty and investigate the impact of customer satisfaction on customer loyalty. Survey questionnaires were delivered to 201 participants in Tangerang City. The design of the sample used in this study was nonprobability sampling with a technique of purposive sampling with the criteria that you have had culinary tours in Tangerang at least 2 times a year. Data collection was obtained for 3 months Descriptive statistics and PLS-SEM were used to analyze the data. This is a quantitative descriptive analysis. The result show that Customer perceived value have a positive and significant effect on customer loyalty and customer satisfaction, experience quality have a positive and significant effect on customer perceived value, customer satisfaction have a positive and significant effect on customer loyalty. The study findings have one hypothesis is not supported. The study's findings will be useful guides for hospitality and tourism in building a more strategically situated approach to customer satisfaction.
Mixture Decompositions using a Decomposition of the Sample Space

We study the problem of finding the smallest $m$ such that every element of an exponential family can be written as a mixture of $m$ elements of another exponential family. We propose an approach based on coverings and packings of the face lattice of the corresponding convex support polytopes and results from coding theory. We show that $m=q^{N-1}$ is the smallest number for which any distribution of $N$ $q$-ary variables can be written as mixture of $m$ independent $q$-ary variables. Furthermore, we show that any distribution of $N$ binary variables is a mixture of $m = 2^{N-(k+1)}(1+ 1/(2^k-1))$ elements of the $k$-interaction exponential family.
Spectral Analysis of the Martian Atmospheric Turbulence: InSight Observations

In this study, we perform spectral analysis of Martian near‐surface turbulence using the in‐situ observations by NASA's InSight lander on Mars. A recent study on the daytime Martian boundary layer using the InSight observations showed that the conventional Kolmogorov energy cascade of inertial subrange fails to predict the spectral density of pressure (Banfield et al., 2020, https://doi.org/10.1038/s41561-020-0544-y). Here we extend this by investigating diurnal and seasonal variations in the spectral density of pressure, as the indicator of the Martian atmospheric turbulence. We show distinct spectral behaviors for the daytime and nighttime conditions. Moreover, we report the important effects of regional dust storms, gravity waves (GWs), bore, and solitary waves on the turbulent energy cascade. Our results show that the presence of a dust storm and GW activity can enhance the turbulence of the nighttime boundary layer of Mars despite the extreme stably stratified conditions compared to the terrestrial case.
Healthy Gut Microbiome Composition Enhances Disease Resistance and Fat Deposition in Tibetan Pigs

The gut microbiota is involved in a range of physiological processes in animals, and modulating the microbiome composition is considered a novel target for identifying animal traits. Tibetan pigs show better fat deposition and disease resistance compared to Yorkshire pigs. However, studies investigating the correlation between favorable characteristics in Tibetan pigs and the gut microbial community remain scarce. In the current study, 1,249,822 high-quality sequences were obtained by amplicon sequencing of the colon contents of Tibetan and Yorkshire pigs. We found that at the boundary level, the abundance and relative abundance of colon bacterial community in Tibetan pigs were higher than that in Yorkshire pigs (P > 0.05). Phylum level, Firmicutes were the dominant colonic microflora of Tibetan and Yorkshire pigs, and the ratio of Firmicutes to Bacteroides in Tibetan pigs was slightly higher than in Yorkshire pigs. Actinobacteria and Spirobacteria were significantly higher in Tibetan pigs than in Yorkshire pigs (P < 0.05). At the genus level, the relative abundance of Bifidobacterium, Lactobacillus, and Bacteriologist, which are related to disease resistance, was significantly higher than that in Yorkshire pigs in Yorkshire pigs. In conclusion, the composition and abundance of colonic intestinal microflora in Tibetan pigs were closely related to their superior traits. Bifidobacteria, Ruminococcaceae, and Family-XIII-AD3011-Group are conducive to improving disease resistance in Tibetan pigs. Lactobacillus and Solobacterium were observed to be the main bacterial communities involved in fat deposition in Tibetan pigs. This study will provide a new reference for the development and utilization of Tibetan pigs in future.
Impact of qualified gatekeepers on team absorptive capacity: the mediating role of knowledge combination capability

Purpose This study aims to examine direct effects of qualified team gatekeepers on absorptive capacity (AC), and the mediating roles of combinative capabilities – knowledge integration capability (KIC) and interteam coordination. Design/methodology/approach A social networking analysis was used to analyze a unique data set collected from all members of 32 Japanese research and development (R&D) teams to identify key individuals who perform daily gatekeeping functions. This study analyzed the data through partial least squares structural equation modeling with higher-order latent variables. Finally, cross-validation tests were used with holdout samples to test the model’s predictive validity. Findings Qualified gatekeepers directly contribute to teams’ realized AC but not to their potential AC. Furthermore, qualified gatekeepers can improve their teams’ capability to absorb and exploit external knowledge by facilitating their capability to consolidate knowledge, that is, its KIC and interteam coordination. Originality/value Unlike prior research that asks top managers to identify team gatekeepers, this study used social network analysis to identify these vital individuals. This study provides a new framework indicating how qualified gatekeepers impact the AC of R&D teams through the examination of both the direct and indirect paths of gatekeeping abilities, two combinative capabilities as mediators and team AC.
Tunable White Light for Elders (TWLITE): A Protocol Demonstrating Feasibility and Acceptability for Deployment, Remote Data Collection, and Analysis of a Home-Based Lighting Intervention in Older Adults

Sleep disturbances are common in older adults and may contribute to disease progression in certain populations (e.g., Alzheimer’s disease). Light therapy is a simple and cost-effective intervention to improve sleep. Primary barriers to light therapy are: (1) poor acceptability of the use of devices, and (2) inflexibility of current devices to deliver beyond a fixed light spectrum and throughout the entirety of the day. However, dynamic, tunable lighting integrated into the native home lighting system can potentially overcome these limitations. Herein, we describe our protocol to implement a whole-home tunable lighting system installed throughout the homes of healthy older adults already enrolled in an existing study with embedded home assessment platforms (Oregon Center for Aging & Technology—ORCATECH). Within ORCATECH, continuous data on room location, activity, sleep, and general health parameters are collected at a minute-to-minute resolution over years of participation. This single-arm longitudinal protocol collected participants’ light usage in addition to ORCATECH outcome measures over a several month period before and after light installation. The protocol was implemented with four subjects living in three ORCATECH homes. Technical/usability challenges and feasibility/acceptability outcomes were explored. The successful implementation of our protocol supports the feasibility of implementing and integrating tunable whole-home lighting systems into an automated home-based assessment platform for continuous data collection of outcome variables, including long-term sleep measures. Challenges and iterative approaches are discussed. This protocol will inform the implementation of future clinical intervention trials using light therapy in patients at risk for developing Alzheimer’s disease and related conditions.