Miracle-dz/UniFAR-FTUs huggingface dataset:
YouTube Channel: An Alternative Social Media to Enhance EFL Students’ Speaking Skill

The use of YouTube channel allows students to comprehend lessons easier and motivates students in learning. The aim of this study is to know whether or not there is a significant effect of using YouTube channel to students’ speaking achievement. YouTube encourages positive learning attitude if it is incorporated in classroom teaching to supplement language learning especially speaking. The design of this study was experimental research that was conducted at English language study program of Universitas Islam Riau. 48 students of the first semester were selected as the sample of the study. After applying YouTube channel in teaching speaking, it was found that the value of sig. 2-tailed was 0.000 which is lower than the probability value of 0.05. It means there was a significant improvement on students’ speaking achievement after being taught by using YouTube channel.
Calculation of active earth pressure against retaining walls under translation mode considering soil arching effect in cohesive soil

In this study, the contour of the soil arch is not assumed as a certain curve, and the soil stress analysis is conducted on a differential element with two dimensions. Herein, analytical expressions of the active earth pressure, active earth force are derived based on the static equilibrium of the differential element. Furthermore, the effects of wall-soil friction angle and soil internal friction angle on the active earth pressure are investigated. Eventually, comparisons among the proposed method of this study and the previous measured data and other analytical approaches yield satisfactory results.
Determinants of Customer Satisfaction and Its Implications on Word of Mouth in E-Commerce Industry: Case Study in Indonesia

The aim of this study is to analyze the effect of several antecedents of customer satisfaction in e-commerce industry, namely web design, time saved, product variety, and delivery performance, and their consequences on customer satisfaction and word of mouth. The investigation used purposive sampling with repeat buyers as criteria. 100 samples were eligible and feasible to test after validity and reliability are concluded. The results show that website design, time saved, and delivery performance are significantly influence on customer satisfaction. In the meantime, website design, time saved, and product variety were effect on word of mouth. In addition, the result also confirms the hidden role of customer satisfaction as intervening variable partially.
Mindfulness for Preventing Psychosocial Risks in the Workplace: A Systematic Review and Meta-Analysis

Organizations today are implementing psychological interventions to promote the job performance and wellbeing of their employees. Mindfulness-based interventions (MBIs) can contribute to providing workers with competencies and skills and develop their strengths. MBIs are therefore becoming more and more present in the workplace, sometimes using online intervention programs, which offer a promising direction in prevention and intervention for health. The objective of this study is to analyze the efficacy of MBIs on psychological variables in the workplace. For this purpose, a search for scientific articles published from 2009 to 2019 was made in the Psicodoc, PsycINFO, and Web of Science databases, where a total of 468 articles were found. After filtering with preestablished inclusion criteria, 24 studies were included in the systematic review and meta-analysis. The results of the meta-analysis suggest that intervention in mindfulness positively influences psychological variables related to employee health and wellbeing. However, it is recommended to continue performing new studies to confirm this finding.
Long-term prediction method of reactive load based on LSTM neural network

In the operation of the power system, the prediction of reactive load can provide accurate data foundation conditions for reactive power compensation planning. Aiming at the characteristics of time series, non-linearity and small fluctuation of power reactive load data, this paper proposes a reactive power load prediction method based on LSTM (long short-term memory) neural network. The proposed method is used to process and predict the power reactive load data of a certain area in Fujian Province. The experimental results show that the LSTM model with one layer and 64 neuron structures have the best result among the support vector regression (SVR), the random forest model (RF), Recurrent Neuron Network (RNN), LSTM-CNN hybrid neural network, the prediction of reactive load on long-term scale has higher accuracy and stability.
Incorporating recombination into the study of recent human evolutionary history

The aim of this work is to use the information left by recombination in our genomes to make inferences on the recent evolutionary history of human populations. For that, a novel method called IRiS has been developed that allows detecting specific past recombination events in a set of extant sequences. IRiS is extensively validated and studied in whole set of different scenarios in order to assess its performance. Once recombination events are detected, they can be used as genetic markers to study the recombinational diversity patterns of human populations. We apply this innovative approach to a whole set of different human populations within the Old World that were specifically genotyped for this end and we provide new insights in the recent human evolutionary history of our species.
Building Connections and Relationships at School: Youth Reflect on Mentoring Their Younger Peers

Most peer mentoring studies have focused on outcomes for mentees. This investigation examines seventh- and eighth-grade youth mentors’ roles in providing support and companionship to younger peer mentees. Group concept mapping (GCM) explored youth mentors’ reflections on the connections and relationships made through a peer mentoring program, 2 to 4 years after participating in the program. Results showed three key concepts: (a) Communication Skills, (b) Relationships With Mentees, and (c) Connections With School and Staff. Mentors noted their improved communication skills with mentees and improved interpersonal relations with fellow mentors and school staff. Implications and future research are discussed.
The Role of Transcription Factors in Regulating Adult Neurogenesis after Excitotoxic Brain Injury

ii Acknowledgements . iii List of Figures . 1 List of Tables . 3 List of Abbreviations. 4 Chapter 1. Literature Review . 7 1.1. Stem Cells . 7 1.2. Developmental Neurogenesis . 8 1.2. 1. Early Forebrain Patterning . 8 1.2. 2. Dorsal Forebrain Neurogenesis . 9 1.2. 3. Ventral Forebrain Neurogenesis . 11 1.2. 4. Neurogenesis-Gliogenesis Switch . 12 1.3. Adult Neurogenesis . 15 1.3. 1. The Subgranular Zone. 16 1.3. 2. The Subventricular Zone . 18 1.3. 3. The Rostral Migratory Stream . 22 1.4. Regulation of Neurogenesis . 25 1.4. 1. Extrinsic Factors . 25 1.4. 2. Intrinsic Factors . 32 1.5. Regulation of Adult Neurogenesis . 35 1.5. 1. Regulation of Type B Neural Stem Cells . 35 1.5. 2. Transition from Neural Stem Cell to Transit Amplifying Precursor Cell . 36 1.5. 3. Oligodendroglial Transit Amplifying Precursor Cells and OPCs . 38 1.5. 4. Neurogenic Transit Amplifying Precursor Cells and Neuroblasts . 38 1.6. Neural Cell Loss and Endogenous Repair . 40 1.6. 1. Acute Brain Injury . 40 1.6. 2. Neurodegenerative Diseases . 48 1.7. Summary . 51 1.8. Hypothesis . 52 1.9. Specific Project Aims . 52
Transcriptomic and metabolomic studies on the protective effect of molecular hydrogen against nuclear electromagnetic pulse-induced brain damage

Background Excessive doses of electromagnetic radiation pose a negative impact on the central nervous system and lead to mental disorders. Molecular hydrogen can scavenge intracellular hydroxyl radicals, acting as an antioxidant, anti-apoptotic and anti-inflammatory agent. We seek to assess the capability of molecular hydrogen to ameliorate brain damage induced by electromagnetic radiation. Methods NEMP (nuclear electromagnetic pulse), a subset of electromagnetic pulse with high voltage value that could cause severe brain injury, was applied to this study. Male wild-type rats were divided into four groups: the control group, the H2 (Molecular hydrogen) group, the NEMP group and the NEMP+H2 group. Rats in the H2 group and the NEMP+H2 group were fed with saturated hydrogen-rich water from 3 days before NEMP exposure (electromagnetic field intensity 400 kV/m, rising edge 20 ns and pulse width 200 ns) to the day of sacrifice. One day after exposure, animal behavior experiments were performed, and samples for transcriptomics and metabolomics analysis were collected. Seven days after exposure, histopathological experiments were conducted. Results The data from the elevated plus maze and the open field test showed that NEMP exposure elicited anxiety-like behavior in rats, which could be alleviated by H2 treatment. Histopathological results manifested that NEMP exposure-induced injuries of the neurons in the hippocampus and amygdala could be attenuated by H2 treatment. Transcriptomic results revealed that NEMP exposure had a profound effect on microtubule structure in the brain. And the combined analysis of transcriptomics and metabolomics showed that H2 has a significant impact on the neuroactive ligand-receptor interaction, synaptic vesicle cycle and synapse etc. Moreover, it was indicated that the glutathione metabolic pathway played a vital role in the NEMP exposure-induced damage and the protective activity of H2. Conclusions H2 is identified as a potent agent against NEMP exposure-induced brain damage and has the potential to be a promising electromagnetic radiation protectant.
The Roles of Patients’ Authenticity and Accepting External Influence, and Clinicians’ Treatment Styles in Predicting Patients’ Dental Anxiety and Avoidance of Dental Appointments

A substantial proportion of adults suffer from high dental anxiety, which is related to poor oral health and functioning. Using authenticity theory and self-determination theory, we applied a model testing two moderated mediation hypotheses: (i) the negative indirect association between authenticity and avoiding dental appointments through dental anxiety would be more evident when clinicians provides higher levels of autonomy support; and (ii) the indirect positive association between accepting external influence and avoiding dental appointments through dental anxiety would be more evident when clinicians provides higher levels of controllingness. Participants (N = 208) responded to a survey with validated questionnaires. The model with hypotheses were tested using Structural Equation Modeling (SEM) in LISREL and Conditional Process Modeling (moderated mediation). The results supported our hypotheses. The SEM model tested was found to fit the data well. Patient’s personality and dental clinic treatment environments predicted 38% of the variance in dental anxiety, which explained 38% of avoidance of treatment.
Induction of an antioxidant enzyme system and other oxidative stress markers associated with compatible and incompatible interactions between chickpea (Cicer arietinum L.) and Fusarium oxysporum f. sp.ciceris

To ascertain if active oxygen species play a role in fusarium wilt of chickpea caused by Fusarium oxysporum f. sp. ciceris, the degree of lipid peroxidation (malondialdehyde formation) and the activity levels of diamine oxidase (DAO), an apoplastic H2O2-forming oxidase, and several antioxidant enzymes, namely ascorbate peroxidase (APX), catalase (CAT), glutathione reductase (GR), guaiacol-dependent peroxidase (GPX) and superoxide dismutase (SOD), were determined spectrophotometrically in roots and stems of ‘WR315’ (resistant) and ‘JG62’ (susceptible) chickpea cultivars inoculated with the highly virulent race 5 of the pathogen. Moreover, APX, CAT, GPX and SOD were also analysed in roots and stems by gel electrophoresis and activity staining; and the protein levels of APX and SOD in roots were determined by Western blotting. In roots, infection by the pathogen increased lipid peroxidation and CAT and SOD activities, although such responses occurred earlier in the incompatible compared with the compatible interactions. APX, GPX and GR activities were also increased in infected roots, but only in the compatible interaction. In stems, infection by the pathogen increased lipid peroxidation and APX, CAT, SOD and GPX activities only in the compatible interaction, and DAO activity only in the incompatible one. In general, electrophoregrams agreed with the activity levels determined spectrophotometrically and did not reveal any differences in isoenzyme patterns between cultivars or between infected and non-infected plants. Further, Western blots revealed an increase in the root protein levels of APX in the compatible interaction and in those of SOD in both compatible and incompatible interactions. In conclusion, whereas enhanced DAO activity in stems, and earlier increases in lipid peroxidation and CAT and SOD activities in roots, can be associated with resistance to fusarium wilt in chickpea, the induction of the latter three parameters in roots and stems along with that of APX, GR (only in roots) and GPX (only in stems) activities are rather more associated with the establishment of the compatible interaction.
Mediating Role of the Positive Psychological Capital on the Relation between the Authentic Leadership Style and Employees Work Engagement: An Applied Study on Hospitality Industry

The most valuable and unique resource that the organizations have under today’s conditions is the human resources. The positive psychology perspective, trying to understand the human resource in all its parts that brings hope, self-efficacy, optimism, and resilience features into the forefront draws attention to utilize this resource in the most effective way. Moreover, the leadership perspectives that discover the positive psychological capital (PsyCap) elements and contribute to the employees’ development becomes more important in the employees’ work engagement. In this context, this study aims at determining the relation between the authentic leadership and employees’ work engagement and mediating role of the PsyCap on this relationship. The study was carried out with 462 employees working at 4 and 5 star hotels in the cities in the Central and Eastern Black Sea regions in Turkey. Validity of the study’s scales was evaluated by explanatory (EFA) and confirmatory factor analyses (CFA) and the relations between the variables that comprise the research design were evaluated by the Structural Equation Model (SEM). Findings reveal that, the authentic leadership has a positive effect on both work engagement and PsyCap and PsyCap has a positive effect on the work engagement. Moreover, it is determined that the PsyCap has a partial mediating role in the authentic leadership’s effect on the work engagement. Bootstrap test results also show that the mediating role of the PsyCap determined is significant. As a result, within the framework of the research variables, it can be stated that authentic leaders affect employees’ work engagement directly with their leadership characteristics and partially by supporting and developing employees’ PsyCap elements.
Temporal Distance and Descriptive Norms on Environmental Behaviors: A Cross-Cultural Examination of Construal-Level Theory

Rapid urbanization has beset sustainable consumption. Although many countries are increasingly taking pro-environmental stances, most countries continue to have a low recycling rate and a high littering rate. This study examines the effect of temporal distance as a part of Construal-Level Theory and descriptive norms on pro- and contra-environmental behaviors (i.e., recycling and littering) cross-culturally. Participants were recruited from the United States and South Korea, and randomly assigned to one of five versions of the survey. Findings indicated stronger intention to recycle for the distant future (only 3-year) and no significant difference for littering. Americans showed higher likelihood to recycle than Koreans while Koreans showed higher likelihood to litter when temporal distance was disregarded. Situational descriptive norms showed significant differences cross-culturally, but the interaction of culture and time distance was not visible. Theoretical implications for Construal-Level Theory research and practical implications for environmental policymakers in encouraging pro-environmental behaviors are discussed.
Influence of N6-Benzyladenine and Sucrose on In Vitro Direct Regeneration and Microrhizome Induction of Kaempferia parviflora Wall. Ex Baker, An Important Ethnomedicinal Herb of Asia

Kaempferia parviflora is an ethnomedicinally important plant. Conventional propagation of K. parviflora is hindered by slow growth rate, long dormancy periods and dual use of rhizomes for seeds as well as marketable produce. In our study, we developed a promising dual-phase micropropagation protocol to increase number of plantlets, survivability, biomass and quality plantlets for mass production. Multiple shoot regeneration was found most successful on Murashige and Skoog (MS) media supplemented with 35.52 μM N6-benzyladenine (BA) in terms of highest number of shoots (22.4 ± 1.84), leaves (29.27 ± 1.30), and roots (17.8 ± 1.72) per explant. High survivability was observed with an acclimatisation percentage of 100% in sterile perlite medium. This method was shown to be preferable compared to conventional propagation in terms of propagation time and number of plantlets. Regenerated in vitro plantlets were then successfully induced to form microrhizomes in MS media with an optimal concentration of 6% (w/v) sucrose. Increase in microrhizome biomass (35.7 ± 2.59 g per flask), number of microrhizomes (5.2 ± 0.78), shoots (8.5 ± 1.58) and roots (8.5 ± 1.58) were observed for this treatment. This investigation successfully highlights the manipulation of single factors in short time frame to produce a simple and efficient alternative propagation method for K. parviflora.
Patients’ self-assessed sleep as a nursing tool during hospital care: A pilot study

Sleep in hospital is considered a challenge from both a patient and a nursing perspective. To enable nurses to promote patients’ sleep during hospital care it is essential to have valid, reliable and useful sleep assessment tools at hand. The aim of the present study was to evaluate and compare the outcomes of objectively estimated sleep and self-reported sleep quality. Data were collected through continuous wrist-worn actigraphy and completion of the Richards–Campbell Sleep Questionnaire (RCSQ) in a pilot study on 25 patients during hospital care. A correlation between mean values for the two assessments was shown for the second night but not for the third night of assessment, and it was concluded that the two assessments might capture different dimensions of sleep. Furthermore, based on a high response rate and an evident feasibility in a nursing context the RCSQ may facilitate person-centered care.
Very High Density Point Clouds from UAV Laser Scanning for Automatic Tree Stem Detection and Direct Diameter Measurement

Three-dimensional light detection and ranging (LiDAR) point clouds acquired from unmanned aerial vehicles (UAVs) represent a relatively new type of remotely sensed data. Point cloud density of thousands of points per square meter with survey-grade accuracy makes the UAV laser scanning (ULS) a very suitable tool for detailed mapping of forest environment. We used RIEGL VUX-SYS to scan forest stands of Norway spruce and Scots pine, the two most important economic species of central European forests, and evaluated the suitability of point clouds for individual tree stem detection and stem diameter estimation in a fully automated workflow. We segmented tree stems based on point densities in voxels in subcanopy space and applied three methods of robust circle fitting to fit cross-sections along the stems: (1) Hough transform; (2) random sample consensus (RANSAC); and (3) robust least trimmed squares (RLTS). We detected correctly 99% and 100% of all trees in research plots for spruce and pine, respectively, and were able to estimate diameters for 99% of spruces and 98% of pines with mean bias error of −0.1 cm (−1%) and RMSE of 6.0 cm (19%), using the best performing method, RTLS. Hough transform was not able to fit perimeters in unfiltered and often incomplete point representations of cross-sections. In general, RLTS performed slightly better than RANSAC, having both higher stem detection success rate and lower error in diameter estimation. Better performance of RLTS was more pronounced in complicated situations, such as incomplete and noisy point structures, while for high-quality point representations, RANSAC provided slightly better results.
Patients’ Attitude and Feeling Toward the Presence of Medical Students in Educational Clinics

Background: Clinical education calls for the interaction between the patient and the medical learner and considering the significance of the patients’ satisfaction and its role in clinical education to learners. Accordingly, the present study aimed to investigate patients’ attitudes and feelings toward the presence of medical students in educational clinics. Materials and Methods: This cross-sectional descriptive study was conducted on 274 patients visiting the clinics in 2018, who were selected by the convenience sampling method. The data were collected using the questionnaire of Izadi et al in two parts and then analyzed by SPSS 16. Results: The results showed that the total score of patients’ attitudes toward the presence of the students was 66.3, which was above the expected average score (i.e., 3). In addition, the total score of patients’ feelings toward the presence of the students was 67.3, which was above the expected average score (i.e., 3). Moreover, the average score of female patients’ feelings toward the presence of the students was significantly lower than that of male patients (P<0.05). Eventually, individuals with education levels below diploma and above bachelors were the most and least comfortable about the presence of the students (P<0.05). Conclusion: Therefore, patients had a positive feeling and attitude toward the presence of the students in the clinics. These factors need to receive more attention to increase the satisfaction and quality of clinical education.
Celastrol inhibits store operated calcium entry and suppresses psoriasis

Introduction: Psoriasis is an inflammatory autoimmune skin disease that is hard to cure and prone to relapse. Currently available global immunosuppressive agents for psoriasis may cause severe side effects, thus it is crucial to identify new therapeutic reagents and druggable signaling pathways for psoriasis. Methods: To check the effects of SOCE inhibitors on psoriasis, we used animal models, biochemical approaches, together with various imaging techniques, including calcium, confocal and FRET imaging. Results and discussion: Store operated calcium (Ca2+) entry (SOCE), mediated by STIM1 and Orai1, is crucial for the function of keratinocytes and immune cells, the two major players in psoriasis. Here we showed that a natural compound celastrol is a novel SOCE inhibitor, and it ameliorated the skin lesion and reduced PASI scores in imiquimod-induced psoriasis-like mice. Celastrol dose- and time-dependently inhibited SOCE in HEK cells and HaCaT cells, a keratinocyte cell line. Mechanistically, celastrol inhibited SOCE via its actions both on STIM1 and Orai1. It inhibited Ca2+ entry through constitutively-active Orai1 mutants independent of STIM1. Rather than blocking the conformational switch and oligomerization of STIM1 during SOCE activation, celastrol diminished the transition from oligomerized STIM1 into aggregates, thus locking STIM1 in a partially active state. As a result, it abolished the functional coupling between STIM1 and Orai1, diminishing SOCE signals. Overall, our findings identified a new SOCE inhibitor celastrol that suppresses psoriasis, suggesting that SOCE pathway may serve as a new druggable target for treating psoriasis.