Miracle-dz/UniFAR-FTUs huggingface dataset:
A review and meta-analysis of the survival rate of adult with osteonecrosis of the femoral head treated with transtrochanteric rotational osteotomy

Background: Osteonecrosis of the femoral head (ONFH) is a progressive disease, and transtrochanteric rotational osteotomy (TRO) is a promising option to treat hip preservation. Compared with outcomes of non-Asian patients, those of Asian patients are different. Once ONFH has progressed to the stage of collapse, total hip arthroplasty (THA) is an unavoidable surgical procedure. However, patients treated with TRO still have a certain rate of femoral head collapse. A meta-analysis was done to comprehensively understand the outcome of TRO surgery for ONFH, in which conversion to THA was used as an endpoint event or the survival rate of patients with ONFH after TRO surgery as an indicator. Methods: We retrieved electronic databases from the inception of the study until June 2022, using the survival rate after TRO surgery or that after conversion to the endpoint event of THA as the effect indicator. The Risk Difference Independent unmatched samples of counting information with 95% confidence intervals (CI) were used to calculate the outcome. Also, subgroup analysis was carried out for Asian and non-Asian patients. Heterogeneity and publication bias analyses were also done for the included studies Results: We pooled 19 studies, all of which were about applying TRO procedure for ONFH. There were 15 cohort studies, 4 case-control studies, and no randomized controlled studies. Based on the information extracted from the reported above (we extracted the relevant independent effect values separately for the case-control studies), this meta-analysis was performed based on a fixed-effect model, and META analysis was performed for an independent unpaired group of the samples. The total hip survival rate after TRO in ONFH was 0.58(95% CI = 0.45–0.72), The survival rate for Asians was: 0.68 (95% CI = 0.51–0.85) and for non-Asians was: 0.41 (95% CI = 0.17–0.64), respectively. Conclusions: The application of TRO surgery in ONFH can effectively relieve patients’ symptoms and they enjoy n a high survival rate, especially for Asian patients. This makes it a promising surgical technique.
Bergamot Essential Oil: A Method for Introducing It in Solid Dosage Forms

Bergamot essential oil (BEO) possess antimicrobial, antiproliferative, anti-inflammatory, analgesic, neuroprotective, and cardiovascular effects. However, it is rich in volatile compounds, e.g., limonene, that are susceptible to conversion and degradation reactions. The aim of this communication was to prepare a conjugate based on a quaternary ammonium chitosan derivative (QA-Ch) and methyl-βCD (MCD), coded as BEO/QA-Ch-MCD, to encapsulate BEO in order to stabilize its volatile compounds, eliminate its unpleasant taste, and convert the oil in a solid dosage form. The obtained conjugate, BEO/QA-Ch-MCD, was highly soluble and had a percentage of extract association efficiency (AE %), in terms of polyphenols and limonene contents, of 22.0 ± 0.9 and 21.9 ± 1.2, respectively. Moreover, stability studies under UV stress in simulated gastric fluid showed that BEO/QA-Ch-MCD was more able to protect polyphenols and limonene from degradation compared to free BEO or BEO complexed with MCD (BEO/MCD). The complexation and subsequent lyophilization allowed the transformation of a liquid into a solid dosage form capable of eliminating the unpleasant taste of the orally administered oil and rendering the solid suitable to produce powders, granules, tablets, etc. These solid oral dosage forms, as they come into contact with physiological fluids, could generate nanosized agglomerates able to increase the stability of their active contents and, consequently, their bioavailability.
Antioxidants in Animal Nutrition: UHPLC-ESI-QqTOF Analysis and Effects on In Vitro Rumen Fermentation of Oak Leaf Extracts

The genus Quercus supplies a large amount of residual material (e.g., bark, acorns, leaves, wood), the valorization of which can favor a supply of antioxidant polyphenols to be used in the pharmaceutical, nutraceutical, or cosmeceutical sector. The recovery of specialized metabolites could also benefit livestock feeding, so much so that polyphenols have gained attention as rumen fermentation modifiers and for mitigating the oxidative imbalance to which farm animals are subject. In this context, leaves of Quercus robur L. from Northern Germany were of interest and the alcoholic extract obtained underwent an untargeted profiling by means of ultra-high-performance liquid chromatography/high-resolution tandem mass spectrometry (UHPLC-HRMS/MS) techniques. As triterpenes and fatty acids occurred, the alcoholic extract fractionation pointed out the obtainment of a polyphenol fraction, broadly constituted by coumaroyl flavonol glycosides and condensed tannins. Total phenol, flavonoid and condensed tannins content assays, as well as antiradical (DPPH● and ABTS+●) and reducing activity (PFRAP) were carried out on the alcoholic extract and its fractions. When the effects on rumen liquor was evaluated in vitro in terms of changes in fermentation characteristics, it was observed that oak leaf extract and its fractions promoted an increase in total volatile fatty acids and differently modulated the relative content of each fatty acid.
Investigation of the DNA Damage and Oxidative Effect Induced by Venlafaxine in Mouse Brain and Liver Cells

Venlafaxine is an antidepressant used worldwide. Therefore, studies to confirm its safe use are mandatory. This report evaluated the drug DNA damage capacity in the brain and liver of ICR mice, and its oxidative effect on DNA, lipids, and proteins, as well as the amount of nitrites, also in the brain and liver. Determinations were made at 2, 6, 12, and 24 h post-treatment, excluding DNA oxidation that was observed at 2 h. The tested doses of venlafaxine were 5, 50, and 250 mg/kg. The results showed DNA damage in the brain with the two more elevated doses of venlafaxine at 2 and 6 h post-treatment and also at 12 h in the liver. The comet assay plus the FPG enzyme showed DNA damage in both organs with all doses. The two high doses increased lipoperoxidation in the two tissues from 6 to 12 h post-administration. Protein oxidation increased with the three doses, mainly from 2 to 12 h, and nitrite content was elevated only with the high dose in the liver. The drug was found to affect both tissues, although it was more pronounced in the liver. Interestingly, DNA oxidative damage was observed even with a dose that corresponds to the therapeutic range. The clinical relevance of these findings awaits further investigations.
Adsorption of 2,4-D and MCPA Herbicides on Carbon Black Modified with Hydrogen Peroxide and Aminopropyltriethoxysilane

The carbon black N-220 surface was subjected to modification through H2O2 oxidation and deposition of aminopropyltriethoxysilane. The pristine (CB-NM) and modified materials (CB-Ox and CB-APTES) were characterized by N2 adsorption–desorption isotherms, scanning electron microscopy, energy-dispersive X-ray spectroscopy (SEM-EDS), thermogravimetry, and FTIR spectroscopy. Carbon black samples were applied as adsorbents for the removal of 2,4-dichlorophenoxyacetic acid (2,4-D) and 2-methyl-4-chlorophenoxyacetic acid (MCPA) herbicides from aqueous solutions. The influence of their surface properties on adsorption efficiency was analyzed and discussed. The results showed that the adsorption of the herbicides was pH-dependent, and the most favorable adsorption was observed in an acidic environment. The experimental data best fit pseudo-second-order and Langmuir models for kinetic and equilibrium data, respectively. The adsorption rate of both the herbicides increased in the order of CB-APTES < CB-Ox < CB-NM and was closely correlated with the mesopore volume of the carbon blacks. The monolayer adsorption capacities were found to be 0.138, 0.340, and 0.124 mmol/g for the adsorption of 2,4-D and 0.181, 0.348, and 0.139 mmol/g for the adsorption of MCPA on CB-NM, CB-APTES, and CB-Ox, respectively. The results showed that the surface chemistry of the adsorbent plays a more important role than its porous structure. Both herbicides were preferably adsorbed on APTES-modified carbon black and were adsorbed the worst on oxidized carbon black (CB-APTES > CB-NM > CB-Ox).
Uncharted Waters: Selling a New Product Robustly

A seller introduces a novel product to an unfamiliar market. The seller sets a price and chooses how much information to disclose about the product to a representative buyer, who may incur a search cost to discover an outside option. The buyer knows her outside option distribution, but the seller knows only its mean and an upper bound on its support, and evaluates any selling strategy by its guaranteed profit. The robustly optimal strategy balances the trade-off between demand and surplus extraction: information design can boost demand by deterring the buyer’s search, but this requires providing her with a high payoff via a low price. I find that full disclosure is optimal only when the search cost is high, and different kinds of partial disclosure policies are optimal for lower search costs. Perhaps surprisingly, the price is not monotone in the search cost. These results shed light on the large variations in information disclosure policies among new products, and suggest that technological advancements that reduce search costs may increase prices and make information provision noisier. ∗Arizona State University, Email: kunzhang@asu.edu I am indebted to Hector Chade for his continuing guidance, encouragement, and support, and I am grateful to Mark Whitmeyer for numerous stimulating conversations and insightful suggestions. I would like to thank Dan Bernhardt, Zach Bethune, Nina Bobkova, Jaroslav Borovička, Jesse Bull, Albin Erlanson, Yuhta Ishii, Navin Kartik, Kyungmin (Teddy) Kim, Tomas Larroucau, Fernando Leiva Bertran, Yue Li, SurajMalladi, Alejandro Manelli, Marcel Pruess, Eddie Schlee, Siyu Shi, Eran Shmaya, Ludvig Sinander, Junze Sun, Ina Taneva, Galina Vereshchagina, Renkun Yang, Xiangqian Yang, Ziwei Wang, Nathan Yoder, John Zhu, and especially Andreas Kleiner, as well as the audience at Arizona, ASU, Andrés Bello, Dongbei, ESSEC, Georgia, HKU, Jinan, Queensland, Stony Brook, the 2022 Stony Brook International Conference on Game Theory, and SEA 92nd Annual Meeting for their helpful comments and suggestions. All errors are my own.
What Factors Determine the Online Consumer Behavior in This Digitalized World? A Systematic Literature

This review study envisioned to address the basic objective that is to investigate determinants of online consumer behavior. A conventional review strategy was used to address the objective raised above, i.e., systematic strategy, and also, the obtained data were analyzed via content analysis. In addition to the above, the study also employed descriptive research design to present the obtained result descriptively. According to the generated findings, purchase intention is the most studied area, which is followed by adoption, and conversely, continuance or repurchase stage of online consumer behavior is the most underresearched area. Perceived usefulness, perceived risk, attitude, perceived ease of use, trust, social influence, subjective norms, perceived enjoyment, security, perceived behavioral control, web design quality, privacy and security concerns, demographic factors (e.g., age, gender, occupation, education, and income), perceived value, service quality, perceived satisfaction, psychological factors (e.g., relative advantage), facilitating conditions, and consumers’ experience are the most influential factors significantly affecting online consumer behavior at large. Therefore, it is advised that industries those are experienced or newcomers in the market to work on the identified factors determining the online consumer behavior, to sustain and achieve success in this dynamic world.
Computation of Nonlinear Free-Surface Flows by a Meshless Numerical Method

A meshless numerical model for nonlinear free surface water waves is presented in this paper. Using the fundamental solution of the Laplace equation as the radial basis functions and locating the source points outside the computational domain, the problem is solved by collocation of boundary points. The present model is first applied to simulate the generation of periodic finite-amplitude waves with high wave steepness and then is employed to simulate the modulation of monochromatic waves passing over a submerged obstacle. Very good agreements are observed when comparing the present results with an analytical solution, experimental data, and other numerical results.
The Minimal Period Problem of Periodic Solutions for Autonomous Superquadratic Second Order Hamiltonian Systems

Abstract In this paper, we study the existence of periodic solutions with prescribed minimal period for superquadratic autonomous second order Hamiltonian systems defined on R n with no convexity assumptions. We use the direct variational approach for this problem on a W 1,2 -space of even functions, and prove new iteration inequalities on Morse indices. Using these tools and the saddle point theorem, we obtain results under precisely Rabinowitz′ superquadratic condition on potential functions. We show that for every T >0 the above mentioned system possesses a T -periodic even solution with minimal period not smaller than T /( n +2).
Recurrences and explicit formulae for the expansion and connection coefficients in series of classical discrete orthogonal polynomials

Two formulae expressing explicitly the difference derivatives and the moments of a discrete orthogonal polynomials {P n (x): Meixner, Kravchuk and Charlier} of any degree and for any order in terms of P n (x) themselves are proved. Two other formulae for the expansion coefficients of a general-order difference derivatives ∇ q f(x), and for the moments x ℓ∇ q f(x), of an arbitrary function f(x) of a discrete variable in terms of its original expansion coefficients are also obtained. Application of these formulae for solving ordinary difference equations with varying coefficients, by reducing them to recurrence relations in the expansion coefficients of the solution, is explained. An algebraic symbolic approach (using Mathematica), in order to build and solve recursively for the connection coefficients between two families of Meixner, Kravchuk and Charlier, is described. Three analytical formulae for the connection coefficients between Hahn–Charlier, Hahn–Meixner and Hahn–Kravchuk are also developed.
Observations of entrainment and time variability in the HH 47 jet

We present new Fabry-Perot images of the HH 47 jet that show the first clear evidence for entrainment in a jet from a young star. The material in the jet moves faster down the axis of the flow and slower at the edges, similar to viscous flow in a pipe. The higher excitation lines occur along the edges of the jet, as expected if entrainment accelerates and heats the ambient material. We confirm previous observations of multiple bow shocks in this system. Together, time variability and entrainment produce much of the observed shock-excited gas in this object. Our data show that the 'wiggles' along the jet are not caused by jet material tied to a spiraling magnetic field, but instead result from time variability, variable ejection angles, or inhomogeneities in the flow. The gas entrained in the HH 47 jet may be atomic; our results do not provide direct evidence that stellar jets drive molecular outflows.
On the Stability and Control of the Bicycle

After some brief history, a mathematical model of a bicycle that has become a benchmark is described. The symbolic equations of motion of the bicycle are given in two forms and the equations are interpreted, with special reference to stability. The mechanics of autostabilization are discussed in detail. The relationship between design and behavior is shown to be heavily speed-dependent and complex. Using optimal linear preview control theory, rider control of the bicycle is studied. It is shown that steering control by an optimal rider, especially at low speeds, is powerful in comparison with a bicycle’s self-steering. This observation leads to the expectation that riders will be insensitive to variations in design, as has been observed in practice. Optimal preview speed control is also demonstrated. Extensions to the basic treatment of bicycle dynamics in the benchmark case are considered so that the modeling includes more realistic representations of tires, frames, and riders. The implications for stability predictions are discussed and it is shown that the moderate-speed behavior is altered little by the elaborations. Rider control theory is applied to the most realistic of the models considered and the results indicate a strong similarity between the benchmark case and the complex one, where they are directly comparable. In the complex case, steering control by rider-lean-torque is feasible and the results indicate that, when this is combined with steer-torque control, it is completely secondary. When only rider-lean-torque control is possible, extended preview is necessary, high-gain control is required, and the controls are relatively complex. Much that is known about the stability and control of bicycles is collected and explained, together with new material relating to modeling accuracy, bicycle design, and rider control.
FREE NON-LINEAR VIBRATION OF A ROTATING THIN RING WITH THE IN-PLANE AND OUT-OF-PLANE MOTIONS

Free non-linear vibration of a rotating thin ring with a constant speed is analyzed when the ring has both the in-plane and out-of-plane motions. The geometric non-linearity of displacements is considered by adopting the Lagrange strain theory for the circumferential strain instead of the infinitesimal strain theory. By using Hamilton's principle, the coupled non-linear partial differential equations are derived, which describe the out-of-plane bending and torsional motions as well as the in-plane bending and extensional motions. During deriving the equations of motion, we discuss how to model the circumferential stress and strain in order to consider the geometric non-linearity. Four models are established: three non-linear models and one linear model. For the four models, the linearized equations of motion are obtained in the neighbourhood of the steady state equilibrium position. Based on the linearized equations of the four cases, the natural frequencies are computed at various rotational speeds and then they are compared. Through the comparison, this study recommends which model is appropriate to describe the non-linear behaviour more precisely.
Numerical Prediction of Particle Distribution of Solid-Liquid Slurries in Straight Pipes and Bends

Abstract Turbulent solid-liquid slurry flows in pipes are encountered in many engineering fields, such as mining. In particular, the distribution of the solids is a serious concern to engineers, but its determination involves considerable technical and economic difficulties. A two-fluid model for the numerical prediction of this parameter is presented. The model is robust and numerically stable, and requires relatively short computer time to provide a converged steady-state solution. The novelty of the proposed model and its better performance compared to similar ones reside in the method of accounting for some key physical mechanisms governing these flows, namely turbulent dispersion, interphase friction, and viscous and mechanical contributions to friction. The model is first validated by comparison with many experimental data available in literature regarding the horizontal pipe case over a wide range of operating conditions: delivered solid volume fraction between 9 and 40%; slurry velocity between 1 m/s and 5.5 m/s; and pipe diameter between 50 and 160 mm. A further comparison was performed with respect to recent experiments concerning a horizontal 90° bend.
Threshold voltage dependence on channel length in amorphous-indium-gallium-zinc-oxide thin-film transistors

A threshold voltage (Vth) dependence on channel length (L) is reported for amorphous-indium-gallium-zinc-oxide thin-film transistors (TFTs). Vth is found to shift negatively with decreasing L and the negative shift is drastic in TFTs with L < 4 μm. Combined analysis of current-voltage (I-V) and capacitance-voltage (C-V) curves shows that the Fermi energy (EF) at flat band shifts towards the conduction band (EC) with decreasing L, hence the negative Vth shift. Using the same analysis, the flat band carrier density (nFB) is also found to increase with decreasing L, revealing unintentional doping of the channel by carrier diffusion from the n+ doped source and drain regions as the cause of the negative Vth shift.
SIMULATION OF STRAIN LOCALIZATION: A REAPPRAISAL OF THE COSSERAT CONTINUUM

Classical continuum models, i.e. continuum models that do not incorporate an internal length scale, suffer from pathological mesh‐dependence when strain‐softening models are employed in failure analyses. In this contribution the governing field equations are regularized by adding rotational degrees‐of‐freedom to the conventional translational degrees‐of‐freedom. This so‐called elasto‐plastic Cosserat continuum model, for which an efficient and accurate integration algorithm and a consistent tangent operator are also derived in this contribution, warrants convergence of the load—deflection curve to a unique solution upon mesh refinement and a finite width of the localization zone. This is demonstrated for an infinitely long shear layer and a biaxial test of a strain‐softening elasto‐plastic von Mises material.
Multilevel Structure of Cellular Detonations in Type Ia Supernovae

This work presents the results of a numerical study of two-dimensional cellular thermonuclear detonations in degenerate C+O matter at densities 106-3×107 g cm-3. We found three levels of detonation cells of very different sizes which correspond to the C-, O-, and Si-reaction length scales. The Si cells are comparable to or even larger than the white dwarf size at densities below 107 g cm-3. In the presence of the cellular structures, the averaged half-reaction length compared to the one-dimensional case increases by the factor of 1.3 for the Si-reaction, and by a factor of 1.6 for the O- and C-reactions. The formation of unreacted pockets and overreacted regions behind the cellular detonation front creates concentration fluctuations in the reaction zone. The composition fluctuations and the reaction length increase may affect the spectra of Type Ia supernovae predicted by delayed-detonation models.
Overlapping Multiple Assignments

This paper studies an allocation problem with multiple assignments, indivisible objects, no endowments and no monetary transfers, where a single object may be assigned to several agents as long as the set of agents assigned the object satisfy a compatibility constraint. It is shown that, on the domain of complete, transitive and strict preferences, group-sorting sequential dictatorships are fully characterized by four different combinations of coalitional strategyproofness, strategyproofness, Pareto efficiency, non-bossiness, group-monotonicity and group-invariance. It is also demonstrated that the characterization in Papai (2001) of sequential dictatorships for the case where assignments are not allowed to overlap is contained in the main result.