Miracle-dz/UniFAR-FTUs huggingface dataset:
The complexifications of pseudo-Riemannian manifolds and anti-Kaehler geometry

In this paper, we first define the complexification of a real analytic map between real analytic Koszul manifolds and show that the complexified map is the holomorphic extension of the original map. Next we define an anti-Kaehler metric compatible with the adapted complex structure on the complexification of a real analytic pseudo-Riemannian manifold. In particular, for a pseudo-Riemannian homogeneous space, we define another complexification and a (complete) anti-Kaehler metric on the complexification. One of main purposes of this paper is to find the interesting relation between these two complexifications (equipped with the anti-Kaehler metrics) of a pseudo-Riemannian homogeneous space. Another of main purposes of this paper is to show that almost all principal orbits of some isometric action on the first complexification (equipped with the anti-Kaehler metric) of a semi-simple pseudo-Riemannian symmetric space are curvature-adapted isoparametric submanifolds with flat section in the sense of this paper.
Quasi-coherent sheaves on the moduli stack of formal groups

The central aim of this monograph is to provide decomposition results for quasi-coherent sheaves on the moduli stack of one-dimensional formal groups. These results will be based on the geometry of the stack itself, particularly the height filtration and an analysis of the formal neighborhoods of the geometric points. The main theorems are algebraic chromatic convergence results and fracture square decompositions. There is a major technical hurdle in this story, as the moduli stack of formal groups does not have the finitness properties required of an algebraic stack as usually defined. This is not a conceptual problem, but in order to be clear on this point and to write down a self-contained narrative, I have included a great deal of discussion of the geometry of the stack itself, giving various equivalent descriptions.
Reduction in thermal stress of marine copepods after physiological acclimation

Abstract We studied the phenotypic response to temperature of the marine copepod Paracartia grani at the organismal and cellular levels. First, the acute (2 days) survival, feeding and reproductive performances at 6–35°C were determined. Survival was very high up to ca. 30°C and then dropped, whereas feeding and fecundity peaked at 23–27°C. An acclimation response developed after longer exposures (7 days), resulting in a decline of the biological rate processes. As a consequence, Q10 coefficients dropped from 2.6 to 1.6, and from 2.7 to 1.7 for ingestion and egg production, respectively. Due to the similarity in feeding and egg production thermal responses, gross-growth efficiencies did not vary with temperature. Respiration rates were less sensitive (lower Q10) and showed an opposite pattern, probably influenced by starvation during the incubations. The acclimation response observed in the organismal rate processes was accompanied by changes in body stoichiometry and in the antioxidant defense and cell-repair mechanisms. Predictions of direct effects of temperature on copepod performance should consider the reduction of Q10 coefficients due to the acclimation response. Copepod population dynamic models often use high Q10 values and may overestimate thermal effects.
Association between bone mineral density at different anatomical sites and both mortality and fracture risk in patients receiving renal replacement therapy: a longitudinal study

Abstract Background The clinical utility of bone mineral density (BMD) measurement by dual-energy X-ray absorptiometry (DXA) is debated in end-stage kidney disease (ESKD). We assessed the ability of BMD measured at different anatomical sites to predict mortality and fracture risk in patients requiring renal replacement therapy (RRT). Methods We reviewed all-cause mortality as well as incident hip and overall fracture risk in RRT patients who had BMD measured at the femoral neck, lumbar spine, arm, head, pelvis and total body as part of their routine follow-up between January 2004 and June 2012 at a single university centre. Results A total of 588 patients were included. The median follow-up was 6.5 years, the mean age was 59.6 years and 57.9% were males. Femoral neck BMD (FNBMD) (normal/high versus low) was negatively associated with mortality in univariate and multivariate analyses (P < .001 and P = .048, respectively). Other sites of BMD measurements were not associated with mortality. In multivariate analysis, FNBMD was negatively associated with hip and any fracture risk (P = .004 and P = .013, respectively). No significant interaction was found between FNBMD and gender or parathyroid hormone (PTH) (P = .112 and P = .794, respectively). Conclusions BMD measured at the femoral neck is predictive of mortality in patients requiring RRT, regardless of modality. Low BMD might be a marker of global patient frailty rather than a direct causal factor in this setting. FNBMD is also a strong predictor of hip and any fracture risk in this population, regardless of bone turnover as assessed by PTH levels. FNBMD is thus an overall prognostic marker in patients requiring RRT.
Hom-quantum groups III: Representations and module Hom-algebras

We study Hom-quantum groups, their representations, and module Hom-algebras. Two Twisting Principles for Hom-type algebras are formulated, and construction results are proved following these Twisting Principles. Examples include Hom-quantum n-spaces, Hom-quantum enveloping algebras of Kac-Moody algebras, Hom-Verma modules, and Hom-type analogs of U_q(sl_2)-module-algebra structures on the quantum planes.
Peripheral Arterial Disease Prevalence in a Population-Based Sample of People with Diabetes on the Caribbean Island of Barbados

Background Peripheral arterial disease (PAD) is a risk factor for amputation and systemic atherosclerotic disease. Barbados has a high diabetes prevalence, and 89% of diabetes-related hospital admissions are for foot problems. Foot examination is infrequent in Barbados primary care. The prevalence and potential risk factors for PAD in people with diabetes in Barbados were studied. Methods Multistage probability sampling was used to select a representative population sample of people ≥25 years of age with known diabetes or fasting blood glucose ≥7 mmol/L or HbA1c ≥6.5%. We administered the Edinburgh claudication questionnaire and assessed the ankle brachial pressure index (ABI) and Doppler waveform in both dorsalis pedis and posterior tibial arteries. Participants were classified into categories based on ABI as follows: PAD ≤0.90 in any leg; borderline 0.91 to 0.99 in one leg and the other not ≤0.90 or >0.4; normal 1.00 to 1.40 in both legs; and non-compressible >1.40 in one leg and the other not ≤0.9. Waveforms crossing the zero-flow baseline were categorised as normal. Multivariable logistic regression assessed the associations of potential risk factors with PAD. Results Of 236 participants (74% response rate, 33% male, median age 58.6 years), 51% had previously diagnosed diabetes. Of nine people with symptoms of definite or atypical claudication, four had PAD and one had non-compressible arteries. ABI prevalence (95% CI) was PAD 18.6% (13.8, 24.6), borderline 21.9% (16.6, 28.4), normal 55.5% (49.4, 61.5) and non-compressible 3.9% (1.6, 9.3). Increasing age and female gender were independently associated with PAD. Over 80% of normal legs (ABI 1.00 to 1.40) had normal posterior tibial and dorsalis pedis waveforms, while only 23% legs with PAD (ABI ≤0.90) had normal waveforms in both arteries (Kappa = 0.43). Conclusion Asymptomatic PAD is common in people with diabetes and requires ABI screening to detect it. Female gender is associated with PAD.
Folate Decorated Multifunctional Biodegradable Nanoparticles for Gastric Carcinoma Active Targeting Theranostics

Introduction Gastric cancer remains a major clinical issue and little progress has been made in the treatment of gastric cancer patients during recent decades. Nanoparticles provide a versatile platform for the diagnosis and treatment of gastric cancer. Methods We prepared 7-ethyl-10-hydroxycamptothecin (SN-38) 125I-radiolabelled biodegradable nanoparticles with folate surface modification (125I-SN-38-FA-NPs) as a novel nanoplatform for targeted gastric carcinoma theranostics. We characterized this system in terms of particle size, morphology, radiostability, and release properties and examined the in vitro cytotoxicity and cellular uptake properties of 125I-SN-38-FA-NPs in MNK 7 and NCI-N7 cells. The pharmacokinetics and biodistribution of 125I-SN-38-FA-NPs were imaged by single photon emission computer tomography (SPECT). An MNK7 tumor-bearing model were established and the in vivo antitumor activity of 125I-SN-38-FA-NPs was evaluated. Results SN-38 was readily radiolabeled with 125I and exhibited high radiostability. Poly-lactic-co-glycolic acid (PLGA) nanoparticles (NPs) were formed by solvent exchange, and displayed spherical morphology of 100 nm in diameter as characterized by dynamic light scattering (DLS) and transmission electron microscopy (TEM). A 2.5-fold greater uptake of 125I-radiolabelled SN-38-loaded folate-decorated PLGA nanoparticles (125I-SN-38-FA-NPs) than 125I-radiolabelled SN-38-loaded PLGA nanoparticles (125I-SN-38-NPs) were record in MKN7 tumor cells. NPs and folate-decorated PLGA nanoparticles (FA-NPs) also had good biocompatibility in methyl thiazolyl tetrazolium (MTT) assays. Pharmacokinetic, biodistribution and SPECT imaging studies showed that 125I-SN-38-FA-NPs had prolonged circulation, were distributed in the reticuloendothelial system, and had high uptake in tumors with a higher tumor accumulation of 125I-SN-38-FA-NPs than 125I-SN-38-NPs recorded at 24 h postinjection. In vivo SN-38-FA-NPs significantly inhibited tumor growth without causing obvious side effects. Conclusion Folate receptor alpha (FOLR1) targeted drug-loaded nanoparticles enable SPECT imaging and chemotherapy, and provide a novel nanoplatform for gastric carcinoma active targeting theranostics.
Riemann Hypothesis may be proved by induction

The transformations of the sum identities for generalized harmonic and oscillatory numbers, obtained earlier in our recent report [1], enable us to derive the new identities expressed in terms of the corresponding square roots of x. At least one of these identities may be applied to prove the Riemann Hypothesis by induction. Additionally using this approach, the new series for Euler's constant gamma has been found.
Lighting Control Including Daylight and Energy Efficiency Improvements Analysis

Energy used for lighting is one of the major components of total energy consumption in buildings. Nowadays, buildings have a great potential to reduce their energy consumption, but to achieve this purpose additional efforts are indispensable. In this study, the need for energy savings evaluation before the implementation of lighting control algorithms for a specified building is highlighted. Therefore, experimental tests have been carried out in a university building with laboratories and other rooms, equipped with KNX building automation system. A dimmable control strategy has been investigated, dependent on daylight illuminance. Moreover, a relationship between external and internal daylight illuminance levels has been evaluated as well. Based on the experimental results, the authors proposed a method for the rough estimation of electrical energy savings. Since, according to the EN 15232 standard, Building Automation and Control Systems (BACS) play an important role in buildings’ energy efficiency improvements, the BACS efficiency factors from this standard have been used to verify the experimental results presented in the paper. The potential to reduce energy consumption from lighting in non-residential buildings by 28% for offices and 24% for educational buildings has been confirmed, but its dependence on specific building parameters has been discussed as well.
Chow--Kuenneth decomposition for special varieties

In this paper we investigate Murre's conjecture on the Chow--K\"unneth decomposition for two classes of examples. We look at the universal families of smooth curves over spaces which dominate the moduli space $\cM_g$, in genus at most 8 and show existence of a Chow--K\"unneth decomposition. The second class of examples include the representation varieties of a finitely generated group with one relation. This is done in the setting of equivariant cohomology and equivariant Chow groups to get equivariant Chow--K\"unneth decompositions.
The Witten equation, mirror symmetry and quantum singularity theory

For any non-degenerate, quasi-homogeneous hypersurface singularity, we describe a family of moduli spaces, a virtual cycle, and a corresponding cohomological field theory associated to the singularity. This theory is analogous to Gromov-Witten theory and generalizes the theory of r-spin curves, which corresponds to the simple singularity A_{r-1}. We also resolve two outstanding conjectures of Witten. The first conjecture is that ADE-singularities are self-dual; and the second conjecture is that the total potential functions of ADE-singularities satisfy corresponding ADE-integrable hierarchies. Other cases of integrable hierarchies are also discussed.
Seroprevalence and Genetic Characterization of Toxoplasma gondii among Children with Neurodevelopmental Disorders in Egypt

Toxoplasma gondii is a parasite with a special predilection for the central nervous system. Toxoplasmosis's contribution to the triggering of many neurodevelopmental disorders was established. This study aimed to detect the seroprevalence and genotypes of T. gondii strains in children with neurodevelopmental disorders. The study included 180 children with neurodevelopmental disorders and 180 children in the control group. Assessment of seropositivity of Toxoplasma IgM and IgG antibodies in patients and controls was carried out. Genetic characterization of T. gondii was obtained by nested polymerase chain reaction (PCR) and restriction fragment length polymorphism (RFLP) technique targeting dense granule gene (GRA6). Our results showed that the overall seroprevalence of T. gondii antibodies in the patient and controls was 35.6% and 11.7%, respectively. Nested PCR showed positivity in 11.1% of the patient group for T. gondii DNA. T. gondii seropositivity rate was significantly high in patients with hydrocephalus and also in patients with epilepsy. Positive nested PCR was significantly high in children with hydrocephalus only. Genotyping using nested PCR-RFLP showed genotype I (80%) followed by atypical strains (20%) with no association with any specific clinical presentation. In conclusion, among toxoplasmosis-positive children with neurodevelopmental disorders, analysis of T. gondii GRA6 locus revealed the predominance of type I genotype followed by atypical strains.
Clinical Characteristics and Long-Term Outcomes of MINOCA Accompanied by Active Cancer: A Retrospective Insight Into a Cardio-Oncology Center Registry

Background Clinical characteristics and long-term outcomes of patients with myocardial infarction with non-obstructive coronary arteries (MINOCA) and cancer are insufficiently elucidated. Objectives We sought to characterize these patients hospitalized in a tertiary cardio-oncology center and to find the potential determinants affecting their long-term mortality. Methods MINOCA was diagnosed in 72 of the 1,011 patients with consecutive myocardial infarction who underwent coronary angiography. Mortality rates and their determinants were analyzed within a median follow-up of 69.2 (37.8–79.9) months. Results Active cancer was identified in 21 (29.2%) of patients with MINOCA and in 113 (12.0%) patients with myocardial infarction and obstructive coronary artery disease (MI-CAD) (p < 0.001). MINOCA patients with cancer were characterized by a higher incidence of anemia (47.6 vs. 21.6%, p = 0.03) and more frequently Takotsubo syndrome (19.1 vs. 2.0%, p = 0.01) than in non-cancer MINOCA. The troponin T/hemoglobin ratio was higher in both cancer MINOCA and MI-CAD groups when compared with their respective non-cancer patients (both p < 0.05). The age and sex-standardized mortality rates were significantly higher in cancer MINOCA (26.7%/year) when compared with non-cancer MINOCA (2.3%/year, p = 0.002) and in cancer MI-CAD (25.0%/year) vs. non-cancer MI-CAD (3.7%/year, p < 0.001). Active cancer (HR 3.12, 95% CI 2.41–4.04) was independently associated with higher long-term mortality, while higher hemoglobin levels (HR 0.93, 95% CI 0.88–0.99, per g/dl) and a MINOCA diagnosis (HR 0.69, 95% CI 0.47–0.97) improved long-term survival. Conclusion Patients with MINOCA were comorbid with cancer more frequently than MI-CAD. In turn, an active malignancy was associated with an unfavorable long-term survival both in MI-CAD population and in patients with MINOCA.
High-Speed and Hardware-Efficient Successive Cancellation Polar-Decoder

This brief presents an algorithm for the processing element (PE) of polar decoder based on 2’s complement representation of logarithmic likelihood ratios. It simplifies computation and alleviates critical path delay of PE. In addition, we propose a low complexity algorithm and <inline-formula> <tex-math notation="LaTeX">${p}$ </tex-math></inline-formula>-node architecture for 2-bits successive-cancellation (SC) polar-decoding scheme. Furthermore, overall SC polar decoder-architecture has been design by incorporating suggested PE architectures as well as <inline-formula> <tex-math notation="LaTeX">${p}$ </tex-math></inline-formula>-nodes to support code-length and code-rate (<inline-formula> <tex-math notation="LaTeX">${r}$ </tex-math></inline-formula>) of 1024 bits and 1/2, respectively. We have synthesized and post-layout simulated our design in UMC 180-nm CMOS process and it occupies an area of 6.1 mm<inline-formula> <tex-math notation="LaTeX">$^{\boldsymbol 2}$ </tex-math></inline-formula> and operates at a maximum clock frequency of 446 MHz. Our decoder delivers a throughput of <inline-formula> <tex-math notation="LaTeX">$298{r}$ </tex-math></inline-formula> Mb/s which is 16% better than the state-of-the-art implementation. It has achieved better throughput efficiency of <inline-formula> <tex-math notation="LaTeX">$1.01{r}$ </tex-math></inline-formula> compared to recently reported works.
University of Alberta Access and Engagement in Treatment-Aided Addiction Recovery: Differences between Men and Women by

Background. Addiction treatment research increasingly recognizes the importance of access factors (i.e., systematic barriers and facilitators) and engagement factors (i.e., perceptions of coercion, motivation, and social networks) as determinants of clients’ response to treatment programs. While gender differences in the natural history of drug use are well documented, few studies examined whether access and engagement systematically differ for adult women versus men seeking treatment for addictions. This study is divided into three Research Objectives. Objective 1: To determine whether men and women differ in variables associated with treatment access. Objective 2: To determine whether men and women differ in perceptual variables associated with treatment engagement. Objective 3: To determine whether men and women differ in quality of engagement early in the process of addiction treatment using a regression analysis including coercion, motivation, social support as independent variables and treatment engagement subscales as dependent variables. Methods. Secondary analysis of data collected from a cohort of clients seeking treatment at an Albertabased residential program. Baseline (N = 328) instruments assessed treatment access variables, including the Social Control Index (SCI), the MacArthur Perceived Coercion Scale (MAPCS), the Stages of Change Readiness and Treatment Eagerness Scale (SOCRATES), and Perceived Social Support from Friends and from Family (PSS Fa-Fr) (Polcin & Weisner, 1999; Gardner et al., 1993; Miller & Tonigan, 1996; Procidano & Heller, 1983). One month later, follow up surveys (n = 273) assessed treatment engagement (TE) variables using a treatment engagement scale from Simpson and Joe, 2004. Results. Demographic analysis revealed gender difference in treatment and drug history. Objective 1: Men and women differed significantly in treatment access; women were more likely mandated to treatment from a formal referral source. Formal referral sources are agencies or individuals external to the individuals operating at an institutional or organizational level. Objective 2: Men and women differed significantly in their perceptions of coercion and social networks but not motivation; women perceived greater coercion from formal sources and more support from their friends. Objective 3: Among alcohol clients only the TEcommitment subscale was significant and the SCI and the SOCRATESAMREC subscale were significant. Among the drug clients the main effects were significant for all TE subscales. The SOCRATES AMREC subscale and the PSS-Fa for TE confidence and rapport were significant, while the SOCRATESTS subscale was significant for all three subscales of the TE. Conclusion. Men and women differ in their experiences prior to entering treatment, engagement in treatment, and perceptions of coercion, motivation, and social networks. These differences reflect to varying degrees socially constructed gender roles.
Assessment of Completeness of Reporting in Randomized Controlled Trials of Acupuncture Therapy for Chronic Obstructive Pulmonary Disease

Objective To assess the completeness of reporting in randomized controlled trials (RCTs) of acupuncture therapy (AT) for chronic obstructive pulmonary disease (COPD). Methods We systematically searched PubMed, Embase, Cochrane Library, Web of Science, China National Knowledge Infrastructure (CNKI), Chongqing VIP (CQVIP), WANFANG Data, and China Biology Medicine (CBM) for studies published from their inception to May 8, 2021. The completeness of reporting was evaluated by CONSORT statement and STRICTA guidelines. Univariate and multivariate regression analyses were performed to preliminarily explore the factors related to completeness of reporting. Results A total of 44 RCTs were included. The overall quality score (OQS) based on the CONSORT statement and STRICTA guidelines ranged from 3 to 26 and 7 to 14, with a median of 10 and 11, respectively. Among the 35 items of the CONSORT statement, 10 items were fully reported with reporting rate > 70%, and 11 items were poorly reported at a rate < 5%. Among the 17 items of the STRICTA guidelines, 10 items were adequately reported with > 70%, and only 3 items were incompletely reported at a rate < 20%. The agreement of most items was determined as “good”, “substantial”, or “moderate”. By regression analysis, publication language (β coefficient: 6.432, 95% CI: 3.202 to 9.663, P <0.001) and funding source (β coefficient: 3.159, 95% CI: 1.045 to 5.273, P =0.004) acted as independent predictors of completeness of reporting according to the CONSORT statement. However, no variables associated with the STRICTA guidelines were identified. Conclusion The completeness of reporting of AT for COPD was inadequate. The condition relatively improved for trials with publication in the English language and funding source. By recommendation, reports should be strictly standardized in accordance with the CONSORT statement and STRICTA guidelines to improve the clinical research evidence of AT for COPD.