Miracle-dz/UniFAR-FTUs huggingface dataset:
Linking seasonal distribution patterns with prey availability in a central‐place forager, the Steller sea lion

Aim We used a novel approach to infer foraging areas of a central‐place forager, the Steller sea lion (Eumetopias jubatus), by assessing changes in the temporal and spatial distribution patterns of sea lions at terrestrial sites. Specifically, our objectives were (1) to classify seasonal distribution patterns of Steller sea lions and (2) to determine to what extent the seasonal distribution of Steller sea lions is explained by seasonal concentrations of prey.
Pollution Assessment Based on Element Concentration of Tree Leaves and Topsoil in Ayutthaya Province, Thailand

Atmospheric aerosol particles containing heavy metal contaminants deposit on the surface of plant leaves and the topsoil. Our aim was to reveal the pollution along an industrial–urban–rural gradient (IURG) in the central provinces of Thailand. Leaf samples from Ficus religiosa and Mimusops elengi were collected along with topsoil samples under the selected trees. Al, Ba, Ca, Cr, Cu, Fe, K, Mg, Mn, Na, Ni, Pb, and Zn concentrations were determined by ICP-OES in soil and plant samples. Soils were not polluted according to the critical value; furthermore, the elemental composition did not differ among the sampling sites of the IURG. The rural site was also polluted due to heavy amounts of untreated wastewater of the adjacent Chao Phraya River. Bioaccumulation factors of Ba, Cu, and Mn was higher than 1, suggesting active accumulation of these elements in plant tissue. Our findings proved that the deposition of air pollutants and the resistance to air pollutants in the case of plant leaves were different and that humus materials of the soils had relevant role in bioaccumulation of Al, Ba, and Cu. At the same time, the geochemical background, the source of pollution, and the local plant species greatly influence the metal content of any given environmental compartment.
Factors Associated with Procedural Thromboembolisms after Mechanical Thrombectomy for Acute Ischemic Stroke

Background and objective: Procedural thromboembolisms after mechanical thrombectomy (MT) for acute ischemic stroke has rarely been studied. We retrospectively evaluated factors associated with procedural thromboembolisms after MT using diffusion-weight imaging (DWI) within 2 days of MT. Materials and Methods: From January 2018 to March 2020, 78 patients with acute ischemic stroke who underwent MT were evaluated using DWI. Procedural thromboembolisms were defined as new cerebral infarctions in other territories from the occluded artery on DWI after MT. Results: Procedural thromboembolisms were observed on DWI in 16 patients (20.5%). Procedural thromboembolisms were associated with old age (73.8 ± 8.18 vs. 66.8 ± 11.2 years, p = 0.021), intravenous (IV) thrombolysis (12 out of 16 (75.0%) vs. 25 out of 62 (40.3%), p = 0.023), heparinization (4 out of 16 (25.0%) vs. 37 out of 62 (59.7%), p = 0.023), and longer procedural time (90.9 ± 35.6 vs. 64.4 ± 33.0 min, p = 0.006). Multivariable logistic regression analysis revealed that procedural thromboembolisms were independently associated with procedural time (adjusted odds ratio (OR); 1.020, 95% confidence interval (CI); 1.002–1.039, p = 0.030) and IV thrombolysis (adjusted OR; 4.697, 95% CI; 1.223–18.042, p = 0.024). The cutoff value of procedural time for predicting procedural thromboembolisms was ≥71 min (area under the curve; 0.711, 95% CI; 0.570–0.851, p = 0.010). Conclusions: Procedural thromboembolisms after MT for acute ischemic stroke are significantly associated with longer procedural time and IV thrombolysis. This study suggests that patients with IV thrombolysis and longer procedural time (≥71 min) are at a higher risk of procedural thromboembolisms after MT for acute ischemic stroke.
Effects of Match-Related Contextual Factors on Weekly Load Responses in Professional Brazilian Soccer Players

This study aimed to quantify the weekly training load distributions according to match location, opponent standard, and match outcome in professional soccer players. Rate-of-perceived-exertion-based training load (sRPE) and distance- and accelerometry-based measures were monitored daily during 52 training sessions and 11 matches performed by 23 players. Athletes who played ≥ 60 min during non-congested weeks were considered for data analysis. The training days close to away matches (e.g., one day before the match = MD-1) presented greater sRPE, distance-based volume measures, and mechanical work (player load) compared to the training days close to home matches (p = 0.001–0.002; effect size (ES) = medium−large). The most distant days of the home matches (e.g., five days before the match = MD-5) presented higher internal and external loads than before away matches (p = 0.002–0.003, ES = medium). Higher sRPE, distance-based volume measures, and mechanical work were found during the middle of the week (e.g., three days before the match, MD-3) before playing against bottom vs. medium-ranking teams (p = 0.001–0.01, ES = small−medium). These metrics were lower in MD-5 before matches against bottom vs. medium-ranking opponents (p = 0.001, ES = medium). Higher values of all external load measures were observed during the training session before winning matches (MD-1) compared to a draw or loss (p < 0.001–0.001, ES = medium−large). In conclusion, the training load distribution throughout the week varied considerably according to match-contextual factors.
Large scale-variability in otolith microstructure and microchemistry: The case study of Diplodus sargus sargus (Pisces: Sparidae) in the Mediterranean Sea

Abstract Pelagic larval duration (PLD) and trace elements in otoliths provide basic information to investigate the dispersal history of marine fishes. Due to the paucity of such information in the Mediterranean region, we assessed PLD, hatching and settlement duration and timing, and otolith microelemental composition of the White Sea bream (Diplodus sargus sargus) from multiple locations (hundreds of kilometers from each other) along the Italian coast (Mediterranean Sea). Otoliths were read to assess PLD and analyzed by a laser ablation inductively coupled plasma mass spectrometer in the core, larval and juvenile regions. PLD ranged from ∼14 to 17 days and significantly changed among locations, similarly to hatching (temporal windows of 10–24 days) and settlement (8–22 days) duration and timing, and microelemental fingerprints. These results show (1) a non-negligible large-scale variability in juvenile fish traits and otolith chemistry ever tested before for any Mediterranean fish; (2) the usefulness to properly estimate those traits and chemical features that may help shed light on spatial patterns of population connectivity and dispersal of marine fishes.
Composição química de folhas de oliveira (Olea europaea L.) da região de Caçapava do Sul, RS

The olive tree (Olea europaea L.) is a plant characteristic of the Mediterranean region that is cultivated in various countries of the world due to the great interest in the production of olives and their oil, which is rich in essential fatty acids. The leaves of the olive tree are an important by-product generated by pruning of trees that have significant amount of phenolic and fatty acids important to health. Given the importance of compounds present in olive leaves and the recent crop in southern Brazil, this study aimed to perform an exploratory study on the proximate composition, total phenolic compounds, fatty acids and minerals present in the leaves of the 'Arbequina' variety from Cacapava do Sul, RS, Brazil. The results showed that the leaves had 8.14±0.24% of total lipids, with an amount of polyunsaturated fatty acids more than half of the total content of fatty acids, in special linolenic acid (18:3n3, 46,7%), which is present in the olive oil in general close to the concentration of 1%. The concentration of total phenolics was 30.21±0.31mg GAE g-1 and the predominant minerals in the leaves were Ca, K, Mg, P and S (between 1153 and 11448mg g-1). The sodium concentration was considered low (65.4±5.20mg g-1). These results demonstrate that the leaves from olive trees cultivated in the region of Cacapava do Sul have great potential for use in dietary supplementation both human and animal because are rich in nutrients
Dose Water Extract of Cinnamon (Cinnamomum Zeylanicum) Exhibits Anti-Diabetic Properties in Cultured 3T3-L1 Adipocytes: A Concurrent Assessment of Adipogenesis, Lipolysis and Glucose Uptakes

Cinnamon is a common spice which is widely advocated for its efficacy controlling of hyperglycemia. However, the mechanism of action has yet to be established for the effect on the blood glucose concentration. Cinnamon was extracted with water and induced to cell line namely 3T3-L1 preadipocyte (American Type cell Culture Collection). The cell proliferation, differentiation (adipogenesis) and glucose uptake activity were assessed by measuring the uptake of radio-labelled glucose. Furthermore, for comparison glucose oxidase assay was also performed by using Glucose Assay Kit (Sigma-Aldrich, Inc). The collected data was statistically analysed using SPSS version 12.0 for any possible differences. This study revealed that there was a significant (P<0.01) increase the activity/adipogenesis. This increase activity was accompanied by significant (P<0.01) increase in the glucose uptake and reduced catalytic activity of lipids (lipolysis). The finding reveals that C. Zeylanicum extract has similar effect to that of insulin activity. The present study suggests that the cinnamon enhances glucose uptakes, reduces the lipid breakdown and resembles insulin activity.
Rearing the corn borer, Ostrinia nubilalis (Hubn.), on a semi-artificial diet

Zusammenfassung Der Maisbohrer, Ostrinia nubilalis, kann in groser Zahl mit Erfolg auf einer halbkunst-lichen Diat aus getrockneten Bohnen, Brauhefe, Agar, Ascorbinsaure und Schimmelpilz-Hemmstoffen gezuchtet werden. Die Zunahme dieser Hemmstoffe uber einen bestimmten Anteil fuhrte zur Entwicklungsverzogerung und Reduktion der Eizahl. Dieselbe Diat ist auch fur die Aufzucht der Noctuide Spodoptera littoralis geeignet.
Alterações fisiológicas e bioquímicas em sementes de café secas em sílica gel e soluções salinas saturadas

O objetivo deste trabalho foi avaliar alteracoes fisiologicas e bioquimicas em sementes de cafe submetidas a secagem rapida, em silica gel, e a secagem lenta, em solucoes salinas saturadas. As sementes foram secas ate que atingissem os seguintes teores de agua: 40, 30, 20, 15, 10 e 5% (base umida). Apos a secagem, uma parte das sementes foi imediatamente avaliada quanto ao desempenho fisiologico e ao perfil de enzimas do processo oxidativo, e outra parte foi avaliada apos armazenagem em condicao hermetica, em câmara fria e seca, por quatro meses. A velocidade de secagem e o teor final de agua tiveram efeito significativo sobre a qualidade fisiologica das sementes. Apos a secagem rapida em silica gel, as sementes toleraram teores finais de agua mais baixos. No entanto, apos a secagem lenta, as sementes com teores finais de agua mais elevados apresentaram maior qualidade. O periodo de armazenamento nao afetou a germinacao, mas prejudicou o vigor das sementes. A secagem rapida apresenta maior potencial de dano ao endosperma do que aos embrioes. O perfil enzimatico das sementes de cafe e afetado pelo teor final de agua e pela velocidade de secagem.
Visualization of Germination Proteins in Putative Bacillus cereus Germinosomes

Bacillus cereus can survive in the form of spores for prolonged periods posing a serious problem for the manufacture of safe shelf-stable foods of optimal quality. Our study aims at increasing knowledge of B. cereus spores focusing primarily on germination mechanisms to develop novel milder food preservation strategies. Major features of B. cereus spores are a core with the genetic material encased by multiple protective layers, an important one being the spores′ inner membrane (IM), the location of many important germination proteins. To study mechanisms involved in germination of B. cereus spores, we have examined the organization of germinant receptors (GRs) in spores′ IM. Previous studies have indicated that in spores of B. cereus ATCC 14579 the L-alanine responsive GR, GerR, plays a major role in the germination process. In our study, the location of the GerR GR subunit, GerRB, in spores was examined as a C-terminal SGFP2 fusion protein expressed under the control of the gerR operon′s promoter. Our results showed that: (i) the fluorescence maxima and integrated intensity in spores with plasmid-borne expression of GerRB-SGFP2 were significantly higher than in wild-type spores; (ii) western blot analysis confirmed the expression of the GerRB-SGFP2 fusion protein in spores; and (iii) fluorescence microscopy visualized GerRB-SGFP2 specific bright foci in ~30% of individual dormant spores if only GerRB-SGFP2 was expressed, but, noticeably, in ~85% of spores upon co-expression with GerRA and GerRC. Our data corroborates the notion that co-expression of GR subunits improves their stability. Finally, all spores displayed bright fluorescent foci upon expression of GerD-mScarlet-I under the control of the gerD promoter. We termed all fluorescent foci observed germinosomes, the term used for the IM foci of GRs in Bacillus subtilis spores. Our data are the first evidence for the existence of germinosomes in B. cereus spores.
INVESTIGATION OF ANTIOXIDANT ACTIVITY AND TOTAL PHENOLIC CONTENT OF VARIOUS FRACTIONS OF AERIAL PARTS OF PIMPINELLA BARBATA (DC.) BOISS

Free radicals play an important role in degenerative diseases. They can also induce nutrition and medicines deterioration. Fortunately, formation of free radical is controlled by a variety of systems which are called "antioxidants". Herbal medicines have been focused as new sources of antioxidants with limited complications. Pimpinella barbata (DC.)Boiss is an annual plant from Apiaceae family. In this study, DPPH radical scavenging assay and FRAP method were used for assaying the antioxidant activity and Folin-Ciocalteu, for quantitative determination of total phenolic content of methanolic, n-hexane, and dichloromethane extract of P.barbata. The antioxidant power in DPPH assay and total phenolics in Folin-Ciocalteu method were evaluated as shown in decreasing order: Methanolic extract > dichloromethane extract > n-hexane extract. In FRAP assay, dichloromethane extract was the most potent while the methanolic extract was the weakest one. In both DPPH assay and Folin-Ciocalteu method, methanolic extract exhibited the highest activity and the most phenolic content respectively while in FRAP test dicholoromethane was shown the highest activity. These results are in agreement with other studies and showed that different tests do not necessarily confirm each other. Key word: Free radicals, Pimpinell barbata (DC.)Boiss, FRAP, DPPH, Total phenolic content.
Identification of regenerative processes in neonatal spinal cord injury in the opossum (Monodelphis domestica): A transcriptomic study

This study investigates the response to spinal cord injury in the gray short‐tailed opossum (Monodelphis domestica). In opossums spinal injury early in development results in spontaneous axon growth through the injury, but this regenerative potential diminishes with maturity until it is lost entirely. The mechanisms underlying this regeneration remain unknown. RNA sequencing was used to identify differential gene expression in regenerating (SCI at postnatal Day 7, P7SCI) and nonregenerating (SCI at Day 28, P28SCI) cords +1d, +3d, and +7d after complete spinal transection, compared to age‐matched controls. Genes showing significant differential expression (log2FC ≥ 1, Padj ≤ 0.05) were used for downstream analysis. Across all time‐points 233 genes altered expression after P7SCI, and 472 genes altered expression after P28SCI. One hundred and forty‐seven genes altered expression in both injury ages (63% of P7SCI data set). The majority of changes were gene upregulations. Gene ontology overrepresentation analysis in P7SCI gene‐sets showed significant overrepresentations only in immune‐associated categories, while P28SCI gene‐sets showed overrepresentations in these same immune categories, along with other categories such as “cell proliferation,” “cell adhesion,” and “apoptosis. ” Cell‐type–association analysis suggested that, regardless of injury age, injury‐associated gene transcripts were most strongly associated with microglia and endothelial cells, with strikingly fewer astrocyte, oligodendrocyte and neuron‐related genes, the notable exception being a cluster of mostly downregulated oligodendrocyte‐associated genes in the P7SCI + 7d gene‐set. Our findings demonstrate a more complex transcriptomic response in nonregenerating cords, suggesting a strong influence of non‐neuronal cells in the outcome after injury and providing the largest survey yet of the transcriptomic changes occurring after SCI in this model.
Different strategies, distinguished cooperation efficiency, and brain synchronization for couples: An fNIRS‐based hyperscanning study

Individuals may employ different strategies when cooperating with others. For example, when two participants are asked to press buttons simultaneously, they may press the buttons as quickly as possible (immediate response strategy) or press them in a delayed pattern (delayed response strategy). Despite recognition of interpersonal brain synchronization (IBS) as a fundamental neural mechanism of cooperation, it remains unclear how various strategies influence cooperative behavior and its neural activities.
Young adult predictors of alcohol dependence up to age 53: A 44-year prospective cohort study of Danish men.

AIMS To examine (1) if there is a positive association between drinking volume in young men and lifetime risk of alcohol dependence (AD) and (2) if there are other associations between young adulthood factors and lifetime risk of AD. DESIGN Prospective cohort study of sons of fathers with alcohol use disorder (AUD) and matched low-risk controls without paternal AUD. SETTING AND PARTICIPANTS A total of 204 men, who were assessed at baseline in 1979 at age 19-20 years, were followed through record linkage with Danish registers and consecutive psychiatric interviews at the ages of 33, 43 and 53 years. MEASUREMENTS AD diagnoses were interview-based according to the Diagnostic and Statistical Manual of Mental Disorders, Third Edition or made by treating clinicians according to the International Classification of Diseases (ICD) Revision 8 (ICD-8) until 1993 and Revision 10 (ICD-10) from 1994.We estimated odds ratios (ORs) with 95% confidence intervals (CI) for the development of AD after adjustment for confounders including smoking, social status, and paternal AUD. FINDINGS The following variables from the examination at age 19-20 independently predicted lifetime AD: alcohol consumption > 21 beverages/week vs 0-21 (OR 2.46, 95% CI 1.22-4.97), police contact (OR= 2.60, 95% CI 1.28-5.28) and institutionalization related to the individual (OR=2.90, 95% CI 1.39-6.02). Compared with <1 beverages/week, the risk for AD did not increase significantly for drinking volume categories: 1-7, 8-14, or 15-21 beverages/week. CONCLUSION Independently of other risk factors in young adulthood, young Danish men's risk for lifetime alcohol dependence appears to be predicted by a drinking volume at age 19-20 years exceeding 21 beverages per week.
Patient perceptions of autologous serum eye drops for severe dry eye disease

Autologous serum eye drops (ASED) have been used for refractory dry eye disease (DED) since 1975 due to the added benefit of nutrients, enzymes, growth factors and other biological agents that are missing from commercial artificial eye drops.1, 2 This paper examines the impact of DED on patients' quality of life in relation to the severity of the disease and the subjective experience of patients using ASED.
Poor sleep associated with overuse of media during the COVID-19 lockdown

1Université de Paris, EA 7330 VIFASOM (Vigilance Fatigue Sommeil et Santé Publique), Paris, France, 2APHP, Hôtel-Dieu, Centre du Sommeil et de la Vigilance, Consultation de pathologie professionnelle Sommeil Vigilance et Travail, Paris, France, 3CESP (Centre de recherche en Épidémiologie et Santé des Populations), Université Paris-Saclay, UVSQ, Univ. Paris-Sud, Inserm U1018, Villejuif, France, 4Southeastern Health Regional Observatory (ORS Paca), Marseille, France and 5AMU, UMR Vitrome, IHU Méditerrannée, IRD, Marseille, France
Anxiety and Avoidance in Adults and Childhood Trauma Are Associated with Negative Religious Coping

Religion as a coping strategy is mostly connected with positive health outcomes. Yet, negative religious coping (NRC) has been associated with rather negative outcomes that affect one’s health. The aim of this study was to explore whether insecure adult attachment and childhood trauma are associated with higher NRC. A sample of Czech adults (n = 531, 51.1 ± 17.2 years; 43.5% men) participated in a survey. As measures, the NRC subscale of the Brief RCOPE, the Experiences in Close Relationships-Revised questionnaire, and the Childhood Trauma Questionnaire-Short Form (CTQ-SF) were used. From the whole sample, 23.7% respondents reported higher NRC. Respondents with higher anxiety in close relationships were more likely to use negative coping strategies, with an odds ratios (OR) of 1.27 (95% confidence interval 1.01–1.59). Similarly, avoidance was associated with negative coping OR = 1.41 (1.13–1.75). Moreover, each subscale of the CTQ-SF revealed a significant association with high summary NRC. Respondents who reported physical neglect scored highest on summary NRC with OR = 1.50 (1.23–1.83) after controlling for sociodemographic variables, but also for anxiety and depression. Our findings support the idea that childhood trauma experience and adult attachment style are associated with higher use of NRC strategies.