Miracle-dz/UniFAR-FTUs huggingface dataset:
The Impact of High-Fidelity Simulation on Nursing Students’ The Impact of High-Fidelity Simulation on Nursing Students’ Flexible and Reflective Thinking in Higher Education Flexible and Reflective Thinking in Higher Education

This study evaluated the effect of high-fidelity simulation with both mannequins and live actors on flexible and reflective thinking of nursing students. Students enrolled in an undergraduate nursing program were recruited to participate in this study. Ninety students, all female, completed both pre-and post-surveys. The researchers conducted a paired samples t -test to determine if there is a statistically significant difference in students’ level of flexible thinking before and after they experienced the high-fidelity simulation. Moreover, we conducted multivariate correlational analysis to examine the relationships between flexible thinking and reflective thinking. In general, statistical results in this study provide empirical support for the values of clinical simulation and debriefing on nursing students’ flexible and reflective thinking. High-fidelity simulation can expose students to controlled and dynamic clinical environments, allowing them to attempt the transfer of theory to practice, learn from collaborative and active learning tasks, and be open-minded to multiple perspectives and in diverse situations. We conclude that critical reflection is an important piece of development in flexible thinking and reflective learning. During the time of post-simulation interactions, students are encouraged to reflect objectively on their performance in each scenario. The input from peers and instructors provides students with the opportunity to assess their personal ability to transfer theory to practice and evaluate if the theory design of the course is providing them with the needed information to care for the clients presented in the clinical simulation scenarios.
Differential Sorting of Pelecypod Valves in the Swash Zone

ABSTRACT Differential sorting of right and left valves of pelecypods was found to be common on Mustang and Padre Island beaches, Texas. Determination of stable orientations of valves in unidirectional flume currents enables one to predict their behavior on a beach washed by obliquely approaching waves. The valves become initially stable with respect to the oblique swash and then are sorted by the backwash. The following swash tends to re-enforce this sorting. Further observations on the beach confirm that opposing valves behave as predicted. The sense of sorting is correlated to the direction of wave approach and hence with the direction of longshore drift. Interpretations of paleodrift directions from R-L sorting may be possible, but the narrowness of the inter-tidal zone in which the sorting takes place, and the rapidity of resorting, plus uncertainties in the hydro-dynamic behavior of fossilized material, dictate extreme care in attempting such analyses.
Relationship between Nurses' Workplace Ostracism, Harmony and Compassionate Goal at Main Mansoura University Hospital

1.ABSTRACT Background: Nursing has a reputation for being a predominantly stressful profession. Ostracism, which is a form of mistreatment in the nursing workplace, is neglected in the nursing profession although it can affect the quality of healthcare services. Aim : This study aims to assess the relationship between nurses' workplace ostracism, harmony and compassionate goal at Main Mansoura University Hospital. Research design : A descriptive correlational research design was used. Methods : A convenience sample consisted of 101 staff nurses were enrolled in the study. Data were collected by using three tools namely workplace ostracism, harmony and compassionate goal scale. Results : The study finding revealed that all of staff nurses were low level regarding workplace ostracism, while more than three quarter of them have high level of harmony and majority of them have a satisfactory level regarding compassionate goal. As well, there was a highly significant relation between workplace ostracism and harmony and a highly significant relation between harmony and compassionate goal. Conclusion : There was a highly significant relation between workplace ostracism and harmony and a highly significant relation between harmony and compassionate goal. Recommendation : Health care organizations must always look for novel approaches to detect the presence of workplace ostracism and investigate its causes, such as work overload, bad role models, or communication styles. As well, encourage nurses to socialize with one another frequently and provide them with opportunity to do so.
RATES OF TREE-ISLAND MIGRATION,

Rates of spruce (Picea engelmannii) and fir (Abies lasiocarpa) tree-island migration were estimated by radiocarbon dating the trails of dead wood left by three krummholz tree islands as they moved downwind across the forest-tundra ecotone on Niwot Ridge, Colorado Front Range. The leeward ends of the tree islands have expanded eastward at average rates of 1.5 to <2.6 cm/yr due to rooting of low horizontal branches; the windward ends of the tree islands have receded eastward at average rates of 0.9 to 1.9 cm/yr due to needle death by freezing or desiccation. The trees are in equilibrium with their environments, or are becoming elongated. Long-term movement rates deter- mined by radiocarbon dating are lower than short-term rates estimated from annual measurements of leeward shoot growth. Changes in the direction of tree-island migration with time show no consistent trends that can be used to reconstruct past changes in winter wind direction. Errors in archeological radiocarbon dates resulting from prehistoric use of old tree-island wood for fuel are unlikely to exceed 100 yr in the Front Range timberline environment.
Evaluation of Encapsulation Potential of Selected Star-Hyperbranched Polyglycidol Architectures: Predictive Molecular Dynamics Simulations and Experimental Validation

Polymers, including non-linear copolymers, have great potential in the development of drug delivery systems with many advantages, but the design requires optimizing polymer–drug interactions. Molecular dynamics (MD) simulations can provide insights into polymer–drug interactions for designing delivery systems, but mimicking formulation processes such as drying is often not included in in silico studies. This study demonstrates an MD approach to model drying of systems comprising either hydrophilic tinidazole or hydrophobic clotrimazole drugs with amphiphilic hyperbranched copolyethers. The simulated drying protocol was critical for elucidating drug encapsulation and binding mechanisms. Experimentally, two polymers were synthesized and shown to encapsulate clotrimazole with up to 83% efficiency, guided by interactions with the hydrophobic core observed in simulations. In contrast, tinidazole is associated with surface regions, indicating capacity differences between drug types. Overall, this work highlights MD simulation of the drying process as an important tool for predicting drug–polymer complex behaviour. The modelled formulation protocol enabled high encapsulation efficiency and opened possibilities for the design of delivery systems based on computationally derived binding mechanisms. This demonstrates a computational–experimental approach where simulated drying was integral to elucidating interactions and developing optimized complexes, emphasizing the value of molecular modelling for the development of drug delivery formulations.
Study the Antibacterial Mechanism of Diclofenac and its Activity Alone or Combined with Ciprofloxacin in Treating Urinary Tract Infection

This study aimed to compare the effects of diclofenac, ciprofloxacin and their combination groups on urine tract infection (U.T.I.s) caused by resistance E coli 0157 H7 in vitro and in vivo. Two hundred urine samples were collected from adult women patients suffering from U.T. I.s from February 2022 to July 2022. The urine specimen was cultured on the blood agar and then incubated at 37°C for (1-2) days; MacConkey agar is the media used for determining the biochemistry results, and identification by Rapidchek test which was performed on typical colonies from the selective plate. The M.I. C effect of Diclofenac began at (25600µg/ml) against resistance E coli 0157H7 while M.I. C of ciprofloxacin it was at (0.96mg/ml), but M.I. C of a combination between (diclofenacn+ciprofloxacin) it was at (400+0.48) mg/ml. Resistance induction assay,with the ciprofloxacin has increased four times, while with the diclofenac has doubled, whilst the combination between (diclofenacn+ciprofloxacin) has no changed after 21 days, according to M.I. C.in the time-kill assay, it was proved that the ciprofloxacin and the combination between (diclofenacn+ciprofloxacin) works after 6 hours, compared to the diclofenac, which started to reduce bacterial counting after 40. After that, the examination was carried out by scanning electronic microscope (S.E.M.) to exam the mechanics of diclofenac,work which was found that it was works as anti-biofilm In this study, forty-eighth (48) rabbits were used and divided into six groups as follow positive control (P.C.), negative control (N.C.), diclofenac (D.C.) in 1mg/kg group, ciprofloxacin (C.I.P.)in7mg/kg group, combination (ciprofloxacin 3.5 mg/kg+diclofenac1mg/kg)COM1 group and combination (ciprofloxacin 1.75 mg/kg+diclofenac1mg/kg) com2 All animals (injected with 0.1 ml in CFU E coli 0157 H7 by urinary catheterization route excepting negative control all group excepting negative control resulted in a significant increase in pus cell, epithelium cell concentration in the urine after three days E coli 0157 H7 infection comparison with negative control while in all experimental period after (14 days) showed no significant (P < 0.05) between positive control (P.C.) and diclofenac treated groups but combination COM1 group and com2 decrease significantly (P< 0.05) after (seven and fourteen) days comparison with positive control. diclofenac can be combined with antibiotics as an anti-virulence agent, enhancing the immune system's ability to eradicate infection
Atmospheric response to the extreme Arctic sea ice conditions in 2007

An atmospheric general circulation model driven with the observed 2007 extreme Arctic sea surface temperatures and sea ice concentrations responds with higher surface air temperature over northern Siberia and the Eastern Arctic Ocean (+3 K), increased heat uptake of the ocean in summer (+40 W m−2) and increased oceanic heat losses in fall (−60 W m−2) compared to a climatological scenario. A pronounced low sea level pressure anomaly over the Eastern Arctic (−200 Pa) reinforces a sea level pressure dipole over the Arctic that has been observed to become an increasingly important feature of the Arctic atmospheric circulation in summer. The anomalous pressure distribution contributes to sea ice transport from the Eastern Arctic and is likely to reinforce the original sea ice extent anomaly. The results thus support assessments of observational data over recent years that sea ice loss may feed back onto the atmospheric circulation in the northern hemisphere. The resulting late summer / early fall (JAS) atmospheric anomalies are very robust, they appear in virtually all of the 40 realizations of the experiment. However, we find no significant continuation of the atmospheric signal into the winter as has been suggested based on atmospheric observational data.
Numerical simulation of 3-D seepage field in the tailings of complex terrain

This paper puts forth a generalization method of 3-D numerical model for finite element analysis of 3-D seepage flow field in the tailing pond of a complex terrain.In this generalization,fitting curves are generated to the data of major control points of topographical profiles,and a curved surface is created from these curves.Then using the curved surfaces a 3-D generalization model can be built.By this method,the 3-D seepage flow was simulated and the results are in good agreement with the measurements.
The helpful effect of vitamin D and coconut oil in modulating the histological disorders of the splenic tissue in hyperglycemic mice

The present study aims to study the effect of vitamin D (Vit. D) or/and coconut oil (C.O) on the splenic histological changes of diabetic adult mice induced by streptozotocin (STZ). The mice were divided into 7 groups (n=10), and the experimental duration was 4 weeks. Group 1 (GpI): control group without any treatment; GpII and GpIII: non-diabetic groups, orally received Vit. D in a dose of 500 IU (6.25 ml)/kg b.w/d or C.O in a dose of 7.5 ml /kg b.w/d ,respectively; GpIV: diabetic group injected i.p. with a single dose of STZ (200 mg/kg bw). Gps V, VI and VII: administration of Vit. D or C.O or both together to diabetic group respectively. The results showed no significant changes in the blood glucose (BG), insulin, and splenic weight in GpII and GpIII. GpIV showed a significant increase in BG, significant decrease in insulin levels, and splenic weight values. GpV recorded a moderate decrease in BG, and a moderate increase in insulin levels and splenic weight atrophy. While GpVI or GpVII showed a marked decrease in BG and an increase in insulin levels and splenic weight increment. Histologically, the splenic sections of control or non-diabetic mice received either Vit. D or C.O showed normal structure of the splenocytes. GpIV showed great numbers of giant cells, disarrangement, interference of red and white pulps, and dilated congested blood vessels. Mild improvement was seen in GpV, while in GpVI or GpVII showed a marked improvement in the splenic tissues. In conclusion, diabetic mice received Vit. D/C. O showed strong anti-hyperglycemic effects to restore the glucose and insulin levels close to normal levels. It also restored the splenic weight and histological architecture close to normal status than those administered Vit. D alone.
Inlet Formation and Evolution of the Sediment Bypassing System: New Inlet, Cape Cod, Massachusetts

ABSTRACT Nauset Spit was breached during a moderate northeast storm on 2 January 1987, forming New Inlet. Factors leading to the breach included a long-term narrowing of the barrier; a 0.5-m storm surge superimposed on near perigean, perihelion, and spring tide conditions; restricted flow through existing inlets, and large differences in tidal range and tidal phase between the ocean and Pleasant Bay. Ultimately, destruction of the foredune ridge and a large hydraulic slope across the barrier (> 1.2 m) facilitated the development of an overwash channel, which led to tidal exchange and inlet formation. As the channel captured an increasingly larger portion of the bay tidal prism, the inlet grew in size from 0.5 km after two months to almost 2.0 km wide by early 1988. Opening of New Inlet increased the tidal range from 1.2 to 1.5 m, which drastically changed the hydraulic character and sediment transport patterns in Pleasant Bay. The opening of New Inlet washed much of the sand from the eroding barrier into the bay. As the dimensions of the inlet increased, the ebb-tidal delta grew in volume reducing the amount of sediment bypassing the inlet. Sand continues to enter the backbarrier building sand shoals and bedforms. The decrease in sand supply to the downdrift barrier caused 100 m to 300 m of shoreline recession immediately south of the inlet from 1990 to 2000. During the past six years the rate of erosion has decreased slightly due to more active transport of sediment past the inlet. The major mechanism of inlet sediment bypassing is accomplished through the breaching of hydraulically more efficient channels through the outer portion of the ebb delta. This process results in the formation of swash bars along the downdrift portion of the delta. These bars are 100 m to 300 m long and attach to the landward beach every 1 to 3 years. Permanent breaching of the spit platform has not occurred at New Inlet due to rapid accretion of Nauset Spit and backbarrier shoals directing ebb flow away from the spit platform.
3D Printing Technologies for Fabrication of Magnetic Materials Based on Metal–Polymer Composites: A Review

Additive manufacturing is a very rapidly developing industrial field. It opens many possibilities for the fast fabrication of complex-shaped products and devices, including functional materials and smart structures. This paper presents an overview of polymer 3D printing technologies currently used to produce magnetic materials and devices based on them. Technologies such as filament-fused modeling (FDM), direct ink writing (DIW), stereolithography (SLA), and binder jetting (BJ) are discussed. Their technological features, such as the optimal concentration of the filler, the shape and size of the filler particles, printing modes, etc., are considered to obtain bulk products with a high degree of detail and with a high level of magnetic properties. The polymer 3D technologies are compared with conventional technologies for manufacturing polymer-bonded magnets and with metal 3D technologies. This paper shows prospective areas of application of 3D polymer technologies for fabricating the magnetic elements of complex shapes, such as shim elements with an optimized shape and topology; advanced transformer cores; sensors; and, in particular, the fabrication of soft robots with a fast response to magnetic stimuli and composites based on smart fillers.
Thresholds for Paleozoic ice sheet initiation

Continental drift and atmospheric greenhouse gas concentrations have each, in turn, been proposed to explain the evolution of Paleozoic climate from early era ice-free conditions to late era continental-scale glaciation, despite continually increasing solar luminosity. To assess the relative roles of continental configuration and atmospheric p CO 2 on the formation of continental-scale ice sheets, we use a coupled ice sheet–climate model to simulate ice sheet initiation at eight different Paleozoic time slices using uniform topography. For each time slice, we simulate the climate at three atmospheric pCO 2 levels (560, 840, and 1120 ppm) and both constant (97.5% of modern) and time-appropriate solar luminosity values. Under constant luminosity, our results indicate that continental configurations favor ice sheet initiation in the mid-Paleozoic (400–340 Ma). After accounting for solar brightening, ice sheet initiation is favored in the early Paleozoic (480–370 Ma) simulations. Neither of these results is consistent with geological evidence of continental-scale glaciation. Changes in atmospheric pCO 2 can reconcile these differences. Sufficiently high ( ≥1120 ppm) or low (≤560 ppm) pCO 2 overcomes paleogeographic and luminosity predispositions to ice-free or ice age conditions. Based on our simulations and geological evidence of glaciation and atmospheric composition, we conclude that atmospheric pCO 2 was the primary control on Paleozoic continental-scale glaciation, while paleogeographic configurations and solar irradiance were of secondary importance.
CT Imaging Assessment of Pancreatic Adenocarcinoma Resectability after Neoadjuvant Therapy: Current Status and Perspective on the Use of Radiomics

Pancreatic adenocarcinoma (PDAC) is the most common pancreatic cancer and is associated with poor prognosis, a high mortality rate, and a substantial number of healthy life years lost. Surgical resection is the primary treatment option for patients with resectable disease; however, only 10–20% of all patients with PDAC are eligible for resection at the time of diagnosis. In this context, neoadjuvant therapy has the potential to increase the number of patients who are eligible for resection, thereby improving the overall survival rate. For patients who undergo neoadjuvant therapy, computed tomography (CT) remains the primary imaging tool for assessing treatment response. Nevertheless, the interpretation of imaging findings in this context remains challenging, given the similarity between viable tumor and treatment-related changes following neoadjuvant therapy. In this review, following an overview of the various treatment options for PDAC according to its resectability status, we will describe the key challenges regarding CT-based evaluation of PDAC treatment response following neoadjuvant therapy, as well as summarize the literature on CT-based evaluation of PDAC treatment response, including the use of radiomics. Finally, we will outline key recommendations for the management of PDAC after neoadjuvant therapy, taking into consideration CT-based findings.
Chemical, Molecular, and Histological Techniques for Detection of Adulteration in some Egyptian Meat Products

HIS study aimed to detect the adulteration of some beef products (burger, sausage, luncheon) using chemical, molecular, and histological techniques. We used a total of 63 beef product samples (21 from each product) collected from Egyptian markets. Based on costs, these samples were categorized into class A (high price), class B (medium price), and class C (low price). Adulteration was detected using the chemical composition to estimate protein%, the high-resolution melting (HRM) approach of the real-time PCR (HRM-PCR) to detect species substitution, and the histological examination to detect the adulterated tissue. The chemical analysis showed significantly higher measured protein % in class A beef products than in Class B and C. Molecular detection of mitochondrial 16S rRNA using HRM-PCR revealed the presence of meat adulteration in class B and C by mixing beef meat with either meat of other animals (donkey, dog, and cat) which normally are not consumed or slaughtered in Egypt or meat of other closely related animal species such as sheep and goat. On the histological level, adulteration was also found as noticed by the presence of a large number of tissues other than meat including bone, cartilage, fat, connective tissue, and large blood vessels, especially in class B and C products. With these data, we could conclude that medium and low-price meat products had a high incidence of adulteration. We argue that this strategy for the detection of meat adulteration might be used to safeguard consumers against food fraud in developing countries like Egypt.
Combining controlled-source seismology and local earthquake tomography to derive a 3-D crustal model of the western Alpine region

SUMMARY We present a newly developed approach of combining controlled-source seismology (CSS) and local earthquake tomography (LET) data to obtain a new 3-D crustal model of the western Alpine region. Our approach combines either data by taking into account the strengths of the individual seismic methods. Our western Alpine 3-D model is primarily based on a welldefined Moho, constrained by CSS and LET data, and includes smooth lateral variations in seismic velocities mainly constrained by LET data, but locally also by CSS data. The consistent combination of results from the two different seismic methods is feasible due to LET Moho elements, as defined by characteristic P-wave velocities and their uncertainty estimates. These uncertainty estimates are based on values of the diagonal element of the resolution matrix, absolute P-wave velocities that are typical for crust and mantle and a specific velocity gradient across the Moho discontinuity. Finally, our definition of LET Moho elements and their uncertainties is validated by comparisons of highest quality Moho results from both methods coinciding in 353 localities. Our model clearly shows three Moho surfaces, being Europe, Adria and Liguria as well as major tectonic structures like suture zones and the high-velocity Ivrea body. In general, it is in a good agreement with previous studies. The biggest differences occur along plate boundaries, where the strong lateral velocity variations arebestresolvedbyLET.DuetothelargernumberofavailableMohoreflectorelementsamore accurate definition of plate boundaries at Moho level is possible and, therefore, new insights in deep lithosphere structures of the Alpine collision zone can be expected. Furthermore, our new 3-D crustal model directly includes a 3-D migrated image of the Ivrea body.