Miracle-dz/UniFAR-FTUs huggingface dataset:
Why Elderly Patients with Ground Level Falls Die Within 30 Days And Beyond

Background: Together with a growing geriatric population in the United States, ground level falls (GLF) are troubling and quickly becoming a significant cause for geriatric trauma deaths. This study describes the factors associated with GLF fall deaths and examines how these factors changed mortality rate over a 3-year follow-up. Methods: A retrospective study was conducted based on the ASU Center of Health Information and Research (CHiR) database. The dataset included 52,391 patients with GLF admissions at 4 Level-I trauma centers in Arizona from 2008-2011. Patients were identified using ICD-9 GLF specific E-codes E885.x to E888.x. 49,138 patients 2, TRISS 2. Conclusion: GLF although considered a low-energy mechanism of injury, is fast becoming a significant cause of mortality among the elderly, beginning immediately after the injury, through intermediate and longer-term follow-up periods. Mortality outcomes were modified only by the unalterable effects of chronic conditions such as cardiac diseases, stroke, cancer, diabetes or liver diseases in subsequent years. We recommend trauma level 1 activation for all elderly patients who suffer GLF with concerns for head injury and emphasis on aggressive head injury management strategies to mitigate GLF-related deaths.
METABOLIC EFFECTS OF DIETARY PROTEINS

Droits d’auteur L'Université de Lausanne attire expressément l'attention des utilisateurs sur le fait que tous les documents publiés dans l'Archive SERVAL sont protégés par le droit d'auteur, conformément à la loi fédérale sur le droit d'auteur et les droits voisins (LDA). A ce titre, il est indispensable d'obtenir le consentement préalable de l'auteur et/ou de l’éditeur avant toute utilisation d'une oeuvre ou d'une partie d'une oeuvre ne relevant pas d'une utilisation à des fins personnelles au sens de la LDA (art. 19, al. 1 lettre a). A défaut, tout contrevenant s'expose aux sanctions prévues par cette loi. Nous déclinons toute responsabilité en la matière.
Duration of untreated psychosis in two Arab samples from Egypt and Saudi Arabia: Clinical and sociocultural correlates

BackgroundThe duration of untreated psychosis (DUP) varies considerably across different cultures and settings. However, cross-cultural studies have mostly been either comparisons between developed and developing countries or comparisons between different ethnic groups in unicultural investigations. Studies comparing more socioculturally related countries, such as Arab countries, are required. To the best of our knowledge, no previous studies have compared DUP between Egypt and Saudi Arabia. AimsThe aims of the study are to determine DUP in two samples of patients with first-episode psychosis from Egypt and Saudi Arabia; to explore the sociodemographic, clinical, and help-seeking characteristics that are associated with DUP in these two groups; to distinguish which of these sociodemographic, clinical and help-seeking correlates the DUP are shared by Egyptian and Saudi Arabian patient groups and which are more culture specific; and to test the hypothesis that severity of illness predicts the length of DUP. MethodsA total of 96 (50 from Egypt and 46 from Saudi Arabia) consecutive attendees at two outpatient clinics with first-episode psychosis were assessed by semistructured interviews. In addition to the determination of DUP and help-seeking contacts, patients were assessed by the Positive and Negative Syndrome Scale. ResultsThe mean DUP was 3.2 and 3.1 years for the Egyptian and Saudi Arabian patient groups, respectively. There were no significant differences between the two groups with regard to most of the variables studied. Variables that significantly correlated with DUP were entered into multiple regression analyses. The final model, which accounted for 56.9% of the variance in DUP, included only two variables: ‘first contact’ and ‘mode of onset’. ConclusionIn the two countries, patients with first-episode psychosis were found to have long DUP. First contact with a traditional (faith) healer and insidious mode of onset of psychosis were the two significant predictors of long DUP. Although severity of negative symptoms, as indicated by Positive and Negative Syndrome Scale negative subscale scores, was correlated with DUP, it could not be retained in the final regression model as a significant predictor. Our hypothesis that severity of illness predicts long DUP had to be rejected. Factors found to influence DUP should be taken into account in early intervention initiatives.
Status Survey and Countermeasures on Normal Senior Students' Teacher's Professional Identity from Education Quality Evaluation and Monitoring Perspective

The survey shows: the normal senior students have a higher "professional expectation and professional efficacy"and lower "professional value and professional volition"; in teachers professional identity and the three dimensions of professional value,professional volition,professional expectation,female normal senior students are significantly better than male normal senior students; the proportion of high or secondary professional expectation of the students from the rural areas is significant higher than that of the urban students. Based on this survey,we propose that teachers 'professional identity should be included in quality monitoring index system of normal students,that the problem of improving teachers professional identity should be emphasized from the stage of teacher education,and that we should take measures to comprehensively improve the professional identity of normal senior students.
Morbidity and mortality pattern at the emergency paediatric unit of Mother and Child Hospital Akure, Nigeria

Background: Morbidity and mortality pattern differs among regions. Also, there may be variations within a nation partly due to availability and cost of health services as well as the health-seeking behavior of the people. Aims: To describe the spectrum and outcome of paediatricmedical emergencies in a free integrated maternal and child health facility in south western Nigeria. Also, the likelihood of death from specific diseases in the setting was evaluated. Methods: The data were analyzed using the Software Package for Social Science (SPSS) version 20.0 (Windows Inc; Chicago, IL, USA). Categorized data were presented as percentages. Using inferential analysis, Odds ratio (OR) and 95% confidence interval (CI) were calculated for common disorders as possible predictors of under-five mortality. P-value <0.05 was considered significant. Results: The total number of under-fives admitted in the EPU during the study period was 2361, with a male preponderance (53.5%); 21.3% were neonates (<1month old), 38.8% post-neonatal infants (1-12months) and the rest (39.9%) aged 13-60months.The commonest emergencies seen in the unit were severe malaria (31.2%), gastroenteritis (16.9%) and pneumonia (8.6%). The overall mortality rate was low (3.7%) with a majority (96.6%) of deaths occurring in the first 24 hours.The commonest causes of death were infections. The case fatality rates (CFR’s) were as follows: septicemia (38.5%), aspiration pneumonitis (10.5%), meningitis (10.0%), severe malnutrition (7.0%), severe malaria (5.6%), gastroenteritis (4.3%), pneumonia (2.9%) and neonatal disorders (2.2%). The most significant predictors of death were septicemia (OR = 17.06, 95% C.I. = 5.46-53.26)and severe malaria (OR = 1.98, 95% C.I. = 1.29-3.03). Conclusion: Infectious diseases are the leading paediatric emergencies and commonest causes of deaths among under-five children in our hospital. The overall outcome of childhood disorders managed in our cost-free facility compared favorably with findings in fee-paying health systems elsewhere in Nigeria. Keywords: morbidity, mortality, paediatric emergencies, Mother and Child Hospital
Quality attributes of pomegranate fruit and co-products relevant to processing and nutrition

Pomegranate is widely cultivated in several parts of the world. Agricultural practices that goes hand in hand with the use of modern technology in harvesting, handling and processing pomegranate fruit often lead to postharvest losses in pomegranate industries. An investigation of the quality attributes and functional properties of pomegranate fruit and their practical applications in processing and nutrition is necessary to make all fruit harvest count. This review presents an overview on the physico-chemical, textural and functional properties of pomegranate fruit and coproducts and their applications in processing and nutrition. Furthermore, some of these properties of pomegranate cultivars grown in different regions were compared and the corresponding unique qualities of the fruit highlighted.
EFFECT OF EARLY HEAT STRESS ON THE PRODUCTIVE PERFORMANCE AND PHYSIOLOGICAL RESPONSE IN SOME LOCAL CHICKEN STRAINS

This experiment was conducted to study the effect of heat stress at early age on heat shock proteins, plasma Triiodothyronine (T3), thermal reaction, productive performance, egg quality, and immune response of Matrouh and Inshas chicks. Seven hundred and twenty, one day old chicks (360 Matrouh chicks and 360 Inshas chicks) were used in this study. Birds from each strain were divided into three groups. The first was not treate and kebt as acontrol group (T1), the birds in the second group were exposed to (42°C-43°C ±1°C) for 4 hrs at three days of age (T2) while birds of the third group were exposed to the same thermal treatment of the second group but at four weeks of age (T3). After these treatments birds of (T1 , T2 and T3) were raised under regular conditions. At 18 weeks of age 90 chicks from each strain (30 birds from each group) were subjected to heat stress (42°C-43°±1°C) for 4 hrs. Blood samples were taken from (5 chicks) before and after this heat stress. At 18 wks of age 5 birds from each treatment group were slaughtered. Blood samples were taken just prior and after heat exposure for analysis. Rectal temperature (RT) and respiration rate (RR) were measured before and after exposure to heat stress. Samples of liver (1g) were frozen in liquid nitrogen for further analysis. The second period of experimental was from sexual maturity till 6 months, on the same birds from previous two strains to study the effect of heat stress on egg quality. The important results obtained were: 1Early heat conditioning birds showed increase on the expression of heat shock proteins (70 and 90). 2Early heat exposure birds had the lowest plasma T3 content compared to control and (T3). 3Early heat exposure birds had significant higher antibody titer against SRBC’s than control. 4Results show that body weights were the highest in early heat exposed groups only in the Matrouh strain. 5Early heat exposure caused lower rectal temperature and respiration rate in both strains. 6Heat stress caused an insignificant increase in plasma total protein, albumin and globulin than that of control birds. 7Heat stress at early age (3-day) improved in some parameters of egg quality and egg weight. Therefore heat stress at early age can improve thermotolerance at maturity then improve in the performance of bird. Keyword: Early heat stress, heat shock protein, T3 hormone, body weights, egg quality.
Incidence of early pregnancy bleeding in the Eastern region of Saudi Arabia

Background: Early pregnancy bleeding (EPB) is defined as bleeding within the first 20 weeks of gestation. Women who present with bleeding in early pregnancy have 30 – 50% probability of having a failed pregnancy. Recent US statistics report that it accounts for 1.6% of all ED visits. Although first-trimester vaginal bleeding is an alarming symptom, there is limited published literature on its incidence, timing, and risk factors and there is no published data from the KSA. Methods: This retrospective cohort study included pregnant women who attended their first antenatal visit between August 2011 and May 2012. Results: The number of participants was 724 women who attended the antenatal clinic for first pregnancy visit. 37.85% of them (274) of developed first trimester vaginal bleeding. 62% experienced mild bleeding, 15.4% had moderate bleeding, 13.9% had spotting, while 4.9% of had severe bleeding. The incidence of threatened miscarriage was the highest (11.5%) followed by incomplete miscarriage (8.8%) and missed carriage (7.7%). The incidence of molar pregnancy in our study of 0.55% was very high. Conclusions: The incidence of first trimester vaginal bleeding is high in our center when compared with figures from published literature. The incidence of threatened miscarriage is low, while the incidence of complete or incomplete miscarriage is relatively high. Similar to other reports from Asia, the incidence of molar pregnancy was very high. Further research is recommended to justify the detected high first trimester vaginal bleeding rates and to identify potentials of prevention or improvement of the outcomes of bleeding.
Perfil bioquímico de tejido foliar de aguacate (Persea americana Mill.) y su relación con la sensibilidad al ataque de muérdago (Familia Loranthaceae)

El aguacate drymifolia es sensible al ataque de muerdago, mientras, Hass y Mendez presentan tolerancia. Esta diferencia podria estar relacionada con los metabolitos secundarios producidos por la planta. Se determino el perfil bioquimico de los aguacates drymifolia , Hass y Mendez, y la relacion con la sensibilidad/tolerancia al muerdago. Se evaluaron 27 individuos drymifolia, un Hass y un Mendez, de tres localidades de Michoacan, Mexico. La extraccion y analisis de los compuestos volatiles se realizo por cromatografia de gases acoplado a espectrometria de masas y los resultados se compararon con los espectros de la biblioteca NIST. Los compuestos mas abundantes fueron estragol, cariofileno, (+)-4-careno y γ-terpineno, con 95.0, 88.0 y 90.1%, del total de 116 compuestos identificados, en drymifolia , Hass y Mendez, respectivamente. En aguacate Hass se identificaron 1,3,4,5,6,7-hexahidro-2,5,5-trimetil 2H-2,4a-etanonaftaleno (0.84%), α-cubebeno (0.33 %), 2,4,6–acido octatrienoico (0.24 %) y α–felandreno (0.21%) y en Mendez, timol (0.06%) pero en ningun individuo drymifolia . Ademas, 2,5-bisbenzaldehido tuvo 21.7X y 19.7X, veces mas concentracion en Hass y Mendez, respectivamente, que en drymifolia . El aguacate drymifolia presento mayor cantidad de metabolitos secundarios, pero los compuestos mas abundantes fueron compartidos en las tres variedades. Los compuestos no detectados en aguacate drymifolia podrian estar relacionados con la tolerancia a muerdago.
Investigative progress in prophylaxis and treatment of ARDS with ambroxol

Ambroxol is probably one of the most promising surfactant stimulating agents. It was paid much attention to its protective action in respiratory system in recent years, Ambroxol was applied in prophylaxis and treatment of ARDS and gained better clinical effect. The mechanism of prophylaxis and treatment of ARDS maybe: (1 ) decreasing release of pro-inflammatory(TNFα, IL-1 ) and correlative cytokines, relieving the manifestation of SIRS in lung; (2 ) enhancing of anti-oxidant defence mechanisms, preventing lung injury by reactive free oxygen radicals (e. g. OH, HOCl); (3 ) stimulating synthesis and excretion of endogenetic pulmonary surfactant (PS) by lung alveolar type Ⅱ cells, preventing degradation of PS by phospholipase A, increasing compliance of lung; (4) relieving destruction potential difference of trachea wall in ARDS. There mayb have better clinical effect in prophylaxis and treatment of ARDS with Ambroxol.
Normal values of biochemical parameters in serum of New Zealand White Rabbits

ÖZET Amaç: Bir organ kompleksi olan laboratuvar hayvanları biyomedikal çalışmalarda insanlar için model olarak kullanılmaktadır. Bu nedenle, laboratuvar hayvanlarının normal fizyolojik değerleri, sağlık durumlarıyla ilgili önemli bilgiler sağlar. Bu çalışmada da Yeni Zelanda tavşanlarının serum normal biyokimyasal değerlerinin belirlenmesi amaçlanmıştır. Yöntem: Toplam 93 (60♂; 33♀) tavşanın kulaklarından kan alındı. Serum örneklerinde biyokimyasal testler yapıldı. Analizler için biyokimyasal parametrelerin belirlenmesinde ticari teşhis kitleri kullanıldı. İstatistiksel olarak, erkek ve dişi tavşana göre değişkenlerin ortalama değerleri arasındaki fark bağımsız sample t-testi ile analiz edildi.
A cancer invasion model combined with CAF aggregates incorporating GM containing a p53 inhibitor.

The objective of this study is to design a cancer invasion model based on an interaction between cancer cells and cancer-associated fibroblasts (CAF) aggregates. The strength of this study is to incorporate gelatin hydrogel microspheres (GM) containing pifithrin-α (PFT) of a p53 inhibitor (GM-PFT) with the CAF aggregates. Incorporation of GM-PFT allowed CAF aggregates to enhance the alpha-smooth muscle actin expression level at a high concentration of PFT. When the cancer cells were co-cultured with the CAF aggregates incorporating GM-PFT, the invasion rate of cancer cells was significantly high compared with CAF aggregates or CAF aggregates incorporating GM with or without the same dose of free PFT as well as two-dimension cultured CAF with or without the same does of PFT. In addition, an inhibitor of matrix metalloproteinase decreased the cancer invasion rate for the CAF aggregates incorporating GM-PFT. It is concluded that the interaction between cancer cells and CAF aggregates incorporating GM-PFT of biological activation needs to realize the invasion of cancer cells even in vitro.
Influence of binding polynomials on feasibility of biochemical reactions

- Each metabolite in a specific biochemical reaction at specified pH and pMg is available as an equilibrated mixture of different charged ions and it is named as "pseudo-isomers or metabolite species". In this study, the establishment of stoichiometry was carried out by considering the sum of the metabolite species taking part in a biochemical reaction at specified pH, pMg, ionic strength I, T and P. The transformed Gibbs free energy change of reaction ) ( 0' G r  for the biochemical conversion of fructose 6-phosphate to fructose 1,6 phosphate in glycolysis pathway was calculated and compared with their corresponding standard Gibbs free energy change of reaction ) ( 0 G r  . The results revealed that that there is significant difference in values of ) ( 0' G r  and ) ( 0 G r  . Thus, it is inferred that the thermodynamic property ) ( 0 G r  is not sufficient to provide a criterion for the spontaneity of biochemical reaction. Transformed Gibbs free energy change must be minimized rather than standard Gibbs free energy change of reaction at the state of equilibrium in the case of biochemical reactions
Intermingled fates of the South China Sea and Philippine Sea plate

Recent studies have shown the extent and nature of the South China Sea (SCS) at the end of spreading by unfolding (i.e. structurally restoring) the Manila slab, which is the subducted part of the SCS, and by identifying the nature of the crustlithosphere (oceanic or thinned continental) from mid-slab P-wave velocity perturbations (dVp) [1,2]. The objective of this paper is to propose a reconstruction of the SCS at the end of seafloor spreading and to discuss its geodynamic consequences in the context of the SCS and Philippine Sea plate (PSP) evolution. Reasonably accurate PSP paleo-latitudes and poorly defined paleo-declinations were primarily used to establish the kinematic evolution of the PSP through time (e.g. [3,4]) until 2016, when Wu et al. [1] introduced new kinematic constraints based on the unfolding and restoration of Southeast Asian slabs. Here, we propose to better constrain the relationship between the SCS, the Huatung basin (HB) and the PSP. Our main target is to bring new light on the challenging problem of SCS subduction initiation along a major shearplate boundary. For that, we build on the new kinematic constraints provided by Wu et al. [1] and consider that the HB was not formed during Tertiary (e.g. [5,6]), but during the early Cretaceous (e.g. [7]). GEOMETRY OF THE SCS OCEANIC DOMAIN AT THE END OF SEAFLOOR SPREADING
A systematic review of the efficacy and tolerability of selective serotonin reuptake inhibitors in the treatment of Chinese patients with depressive disorders

quality was also moderate at best. “Randomised” and “doubleblinding” were written only in titles and abstracts of 34 studies. Seven studies had no abstract. 27 studies (44%) had no English abstract. 29 Studies (46.8%) failed to report Dropout rates. An overview of other items, which are not explicitly evaluated in CONSORT, is presented in Table 15. Table 15. Frequency and percentage of items related to reporting quality reported in the 62 included Chinese double-blind RCTs. Information reported Frequency Percentage Informed consent 20 32.3 Financial support 5 8.1 ITT 11 17.7 Dropout due to side effects 19 30.7 No dropout 1 1.6 Dropout rate of 0-5% 13 21.0 Dropout rate of 6-10% 13 21.0 Dropout rate of more than 11% 6 9.7 Email address of corresponding author 14 22.6 ITT: intention-to-treat Furthermore, three pairs of publications [32] and [67], [35] and [60], [47] and [34] showed striking similarities in both text and figures. In addition, another study [80] was found to have similarities with a study [155] which was excluded because of single-blinded design. All pairs were conducted in different groups and regions. Contact details for the corresponding author were only provided for one study, thus further exploration was not possible. 3.3 Efficacy and tolerability measures The forest plots of the analyses are presented in Appendix 6 (Analyses 1.1-14.4). MH RR of response rate and remission rate lower than one indicate a difference in favor of the control group; whilst MH RR of dropout rate lower than one indicates a difference in favor of the
Prevalence and Risk Factors of Disordered Eating Attitudes and Behaviors Among High-school Girls in Al-Madinah City, Saudi Arabia

To determine the prevalence of disordered eating attitudes and behaviors among high-school girls in Al-Madinah City, Saudi Arabia. A cross-sectional descriptive study was conducted in Al-Madinah city in 2014-15. A multi- stage random sampling technique was adopted to include female students of government secondary schools. The Eating Attitudes Test (EAT-26) and socio-economical questionnaires were used in the study for assessing the prevalence of disordered eating. All data were entered and analyzed using SPSS version 20. Overweight and obesity were reported among 11.2% and 5.6% of them, respectively, whereas 31.3% of the participants were underweight. The overall prevalence of disordered eating attitudes among female students was 42.5%. This rate was significantly higher among younger (≤16 years old) and those of the first scholastic level than others. The rate of disordered eating attitude was reported at a higher rate among obese students (59.1%) than underweight (41.5%) and normal students (42.4%). The commonest reported disordered eating behavior was self-reported binge eating behaviour (25.2%), followed by self-induced vomiting (8.7%) and the use of laxatives/ diuretics to control weight (6.1%). The findings show a high prevalence of disordered eating attitude among high school female students in Al-Madinah city. Younger girls and those of the first scholastic level showed higher disordered eating attitude.