Miracle-dz/UniFAR-FTUs huggingface dataset:
Applicability of the Klein-Gordon equation for pair production in vacuum and plasma.

In this paper, a phase-space description of electron-positron pair creation will be applied, based on a Wigner transformation of the Klein-Gordon equation. The resulting theory is similar in many respects to the equations from the Dirac-Heisenberg-Wigner formalism. However, in the former case, all physics related to particle spin is neglected. In the present paper we compare the pair-production rate in vacuum and plasmas, with and without spin effects, in order to evaluate the accuracy and applicability of the spinless approximation. It is found that for modest frequencies of the electromagnetic field the pair production rate of the Klein-Gordon theory is a good approximation to the Dirac theory, provided the matter density is small enough for Pauli blocking to be neglected, and a factor of 2 related to the difference in the vacuum energy density is compensated for.
Quantum Theory without the Axiom of Choice, and Lefschetz Quantum Physics

In this paper, we discuss quantum formalisms that do not use the axiom of choice. We also consider the fundamental problem that addresses the (in)correctness of having the complex numbers as the base field for Hilbert spaces in the København interpretation of quantum theory, and propose a new approach to this problem (based on the Lefschetz principle). Rather than a theorem–proof paper, this paper describes two new research programs on the foundational level, and focuses on basic open questions that arise in these programs.
Feature-Scale Simulations of Particulate Slurry Flows in Chemical Mechanical Polishing by Smoothed Particle Hydrodynamics

In this paper, the mechanisms of material removal in chemical mechanical polishing (CMP) processes are investigated in detail by the smoothed particle hydrodynamics (SPH) method. The feature-scale behaviours of slurry flow, rough pad, wafer defects, moving solid boundaries, slurry-abrasive interactions, and abrasive collisions are modelled and simulated. Compared with previous work on CMP simulations, our simulations incorporate more realistic physical aspects of the CMP process, especially the effect of abrasive concentration in the slurry flows. The preliminary results on slurry flow in CMP provide microscopic insights on the experimental data of the relation between the removal rate and abrasive concentration and demonstrate that SPH is a suitable method for the research of CMP processes.
LeTI: Learning to Generate from Textual Interactions

Fine-tuning pre-trained language models (LMs) is essential for enhancing their capabilities. Existing techniques commonly fine-tune on input-output pairs (e.g., instruction tuning) or with numerical rewards that gauge the output quality (e.g., RLHF). We explore LMs' potential to learn from textual interactions (LETI) that not only check their correctness with binary labels but also pinpoint and explain errors in their outputs through textual feedback. Our focus is the code generation task, where the model produces code based on natural language instructions. This setting invites a natural and scalable way to acquire textual feedback: the error messages and stack traces from code execution using a Python interpreter. LETI iteratively fine-tunes the model, using the LM objective, on a concatenation of natural language instructions, LM-generated programs, and textual feedback. Prepended to this fine-tuning text, a binary reward token is used to differentiate correct and buggy solutions. LETI requires no ground-truth outputs for training and even outperforms a fine-tuned baseline that does. LETI not only improves the performance of LMs on a code generation dataset MBPP, but also generalizes to other datasets. Trained on MBPP, it achieves comparable or better performance than the base LMs on unseen problems in HumanEval. Furthermore, compared to binary feedback, we observe that textual feedback leads to improved generation quality and sample efficiency, achieving the same performance with fewer than half of the gradient steps. LETI is equally applicable in natural language tasks when they can be formulated as code generation, which we empirically verified on event argument extraction.
Multi-Grained Knowledge Retrieval for End-to-End Task-Oriented Dialog

Retrieving proper domain knowledge from an external database lies at the heart of end-to-end task-oriented dialog systems to generate informative responses. Most existing systems blend knowledge retrieval with response generation and optimize them with direct supervision from reference responses, leading to suboptimal retrieval performance when the knowledge base becomes large-scale. To address this, we propose to decouple knowledge retrieval from response generation and introduce a multi-grained knowledge retriever (MAKER) that includes an entity selector to search for relevant entities and an attribute selector to filter out irrelevant attributes. To train the retriever, we propose a novel distillation objective that derives supervision signals from the response generator. Experiments conducted on three standard benchmarks with both small and large-scale knowledge bases demonstrate that our retriever performs knowledge retrieval more effectively than existing methods. Our code has been made publicly available at https://github.com/18907305772/MAKER.
Warm Molecular Gas in the Central Parsecs of the Buried Nucleus of NGC 4418 Traced with the Fundamental CO Rovibrational Absorptions

We investigated the inner buried nucleus of a nearby luminous infrared galaxy, NGC 4418, using high-resolution spectroscopy of fundamental carbon monoxide (CO) rovibrational absorptions around 4.67 μm for the first time. This method allowed us to examine the physical and kinematical properties in the hot inner region of this nucleus. We detected a series of both very deep (partly saturated) 12CO and moderately deep (optically thin) 13CO absorption lines and inferred a large column density (N H2 = (5 ± 3) × 1023 cm−2 in front of the 5 μm photosphere) of warm (T ex ≃ 170 K) molecular gas by assuming an isothermal plane-parallel slab illuminated by a compact background mid-infrared-emitting source. We modeled that the warm CO absorber almost covers the central heating source and that it is an inner layer around the 5 μm photosphere (at r = several parsecs) of a compact shroud of gas and dust (d ∼ 100 pc). The width of the absorption lines (110 km s−1) and their small deviation from the systemic velocity (<10 km s−1) are consistent with a warm and turbulent layer with little bulk motion in the radial direction.
One Fits All: Power General Time Series Analysis by Pretrained LM

Although we have witnessed great success of pre-trained models in natural language processing (NLP) and computer vision (CV), limited progress has been made for general time series analysis. Unlike NLP and CV where a unified model can be used to perform different tasks, specially designed approach still dominates in each time series analysis task such as classification, anomaly detection, forecasting, and few-shot learning. The main challenge that blocks the development of pre-trained model for time series analysis is the lack of a large amount of data for training. In this work, we address this challenge by leveraging language or CV models, pre-trained from billions of tokens, for time series analysis. Specifically, we refrain from altering the self-attention and feedforward layers of the residual blocks in the pre-trained language or image model. This model, known as the Frozen Pretrained Transformer (FPT), is evaluated through fine-tuning on all major types of tasks involving time series. Our results demonstrate that pre-trained models on natural language or images can lead to a comparable or state-of-the-art performance in all main time series analysis tasks, as illustrated in Figure 1. We also found both theoretically and empirically that the self-attention module behaviors similarly to principle component analysis (PCA), an observation that helps explains how transformer bridges the domain gap and a crucial step towards understanding the universality of a pre-trained transformer.The code is publicly available at https://github.com/DAMO-DI-ML/One_Fits_All.
Mechanization of scalar field theory in (1+1)-dimensions: BPS mech-kinks and their scattering

We present an updated version of a general-purpose collective coordinate model that aims to fully map out the dynamics of a single scalar field in (1+1)-dimensions. This is achieved by a procedure that we call a `mechanization': we reduce the infinite number of degrees of freedom down to a finite and controllable number by chopping the field into flat segments connected via joints. In this paper, we introduce two new ingredients to our procedure. The first is a manifestly BPS mechanization in which BPS mech-kinks saturate the same bound on energy as their field-theoretical progenitors. The second is allowing the joints to `switch', leading to an extended concept of the effective Lagrangian, through which we describe direct collisions of mech-kinks and anti-kinks.
Black Americans, hospitalization, and advance care planning: Structural vulnerability in Home Health Value-Based Purchasing

Skilled home health (HH) is the largest long-term care setting and the fastest-growing site of healthcare in the United States (U.S.). Home Health Value-Based Purchasing (HHVBP) is a structure of Medicare that penalizes U.S. HH agencies for high hospitalization rates. Prior studies have shown inconsistent evidence about associations of race with hospitalization rates in HH. Evidence supports that Black or African Americans are less likely to participate in advance care planning (ACP), or to complete written advance directives, which could affect their potential for hospitalization when nearing end of life. In this quasi-experimental study, we used Medicare administrative datasets, the Weighted Acute Care Services Use Rates (WACSUR) score, and the Advance Care Planning Protocol (ACPP) score to determine whether the proportion of Black HH patients in the U.S. was correlated with acute care use rates and the robustness of agency protocols on ACP. We used primary and secondary data from the U.S. from 2016-2020. We included Medicare-certified HH agencies. Spearman’s correlation coefficient was used. We found a statistical trend showing that the greater proportion of Black patients enrolled in a HH agency, the greater tendency to have a high hospitalization rate. Our findings suggest that HHVBP may encourage patient selection and exacerbate health disparities. Our findings support recommendations for alternative measures of quality in HH to include measures of goal-concordant care coordination when patients are denied admission to HH.
Negative symptoms in children and adolescents with early-onset psychosis and at clinical high-risk for psychosis: systematic review and meta-analysis

Background Early-onset psychosis (EOP) refers to the development of a first episode of psychosis before 18 years of age. Individuals at clinical high risk for psychosis (CHR-P) include adolescents and young adults, although most evidence has focused on adults. Negative symptoms are important prognostic indicators in psychosis. However, research focusing on children and adolescents is limited. Aims To provide meta-analytical evidence and a comprehensive review of the status and advances in the diagnosis, prognosis and treatment of negative symptoms in children and adolescents with EOP and at CHR-P. Method PRISMA/MOOSE-compliant systematic review (PROSPERO: CRD42022360925) from inception to 18 August 2022, in any language, to identify individual studies conducted in EOP/CHR-P children and adolescents (mean age <18 years) providing findings on negative symptoms. Findings were systematically appraised. Random-effects meta-analyses were performed on the prevalence of negative symptoms, carrying out sensitivity analyses, heterogeneity analyses, publication bias assessment and quality assessment using the Newcastle–Ottawa Scale. Results Of 3289 articles, 133 were included (n = 6776 EOP, mean age 15.3 years (s.d. = 1.6), males = 56.1%; n = 2138 CHR-P, mean age 16.1 years (s.d. = 1.0), males = 48.6%). There were negative symptoms in 60.8% (95% CI 46.4%–75.2%) of the children and adolescents with EOP and 79.6% (95% CI 66.3–92.9%) of those at CHR-P. Prevalence and severity of negative symptoms were associated with poor clinical, functional and intervention outcomes in both groups. Different interventions were piloted, with variable results requiring further replication. Conclusions Negative symptoms are common in children and adolescents at early stages of psychosis, particularly in those at CHR-P, and are associated with poor outcomes. Future intervention research is required so that evidence-based treatments will become available.
The ComRS-SigX Pathway Regulates Natural Transformation in Streptococcus ferus

Natural transformation is the process by which bacteria take up DNA and allows for acquisition of new genetic traits, including those involved in antibiotic resistance. This study demonstrates that the understudied species Streptococcus ferus is capable of natural transformation using a peptide-pheromone system like that previously identified in Streptococcus mutans and provides a framework for future studies concerning this organism. ABSTRACT The ability to take up and incorporate foreign DNA via natural transformation is a well-known characteristic of some species of Streptococcus, and is a mechanism that rapidly allows for the acquisition of antibacterial resistance. Here, we describe that the understudied species Streptococcus ferus is also capable of natural transformation and uses a system analogous to that identified in Streptococcus mutans. S. mutans natural transformation is under the control of the alternative sigma factor sigX (also known as comX), whose expression is induced by two types of peptide signals: CSP (competence stimulating peptide, encoded by comC) and XIP (sigX-inducing peptide, encoded by comS). These systems induce competence via either the two-component signal-transduction system ComDE or the RRNPP transcriptional regulator ComR, respectively. Protein and nucleotide homology searches identified putative orthologs of comRS and sigX in S. ferus, but not homologs of S. mutans blpRH (also known as comDE). We demonstrate that natural transformation in S. ferus is induced by a small, double-tryptophan containing sigX-inducing peptide (XIP), akin to that of S. mutans, and requires the presence of the comR and sigX orthologs for efficient transformation. Additionally, we find that natural transformation is induced in S. ferus by both the native XIP and the XIP variant of S. mutans, implying that cross talk between the two species is possible. This process has been harnessed to construct gene deletions in S. ferus and provides a method to genetically manipulate this understudied species. IMPORTANCE Natural transformation is the process by which bacteria take up DNA and allows for acquisition of new genetic traits, including those involved in antibiotic resistance. This study demonstrates that the understudied species Streptococcus ferus is capable of natural transformation using a peptide-pheromone system like that previously identified in Streptococcus mutans and provides a framework for future studies concerning this organism.
Prototypicality analysis of the Comprehensive Assessment of Psychopathic Personality (CAPP): A cross‐cultural perspective

The Comprehensive Assessment of Psychopathic Personality (CAPP) model is a new lexically based concept of psychopathy that has potential clinical utility. The main purpose of this research is to investigate the generalizability of the CAPP conceptual model in South Korea. In the current study, 88 experts and 1727 laypeople in South Korea were asked to evaluate the prototypicality of the symptoms of psychopathy (CAPP items) by using a Korean translation of the CAPP model (K‐CAPP). In addition, 11 international prototypicality studies were systematically compared to the ratings by experts in the present study. As a result, it indicated that Korean experts and laypeople, on average, rated K‐CAPP symptoms as moderately to highly prototypical of psychopathy, and more prototypical of psychopathy than symptoms theoretically unrelated to psychopathy (foils). Also, prototypicality ratings of K‐CAPP symptoms made by those two groups were similar to each other as well as to ratings by experts and laypeople using the CAPP in other 11 countries. In conclusion, these results clearly show that both experts and laypeople in the current study conceptualized PPD in almost the same way as experts and laypeople from previous studies using the CAPP model.
Re-irradiation for recurrent/progressive pediatric brain tumors: from radiobiology to clinical outcomes

ABSTRACT Introduction Brain tumors are the most common solid tumors in children. Neurosurgical excision, radiotherapy, and/or chemotherapy represent the standard of care in most histopathological types of pediatric central nervous system (CNS) tumors. Even though the successful cure rate is reasonable, some patients may develop recurrence locally or within the neuroaxis. Area covered The management of these recurrences is not easy; however, significant advances in neurosurgery, radiation techniques, radiobiology, and the introduction of newer biological therapies, have improved the results of their salvage treatment. In many cases, salvage re-irradiation is feasible and has achieved encouraging results. The results of re-irradiation depend upon several factors. These factors include tumor type, extent of the second surgery, tumor volume, location of the recurrence, time that elapses between the initial treatment, the combination with other treatment agents, relapse, and the initial response to radiotherapy. Expert opinion Reviewing the radiobiological basis and clinical outcome of pediatric brain re-irradiation revealed that re-irradiation is safe, feasible, and indicated for recurrent/progressive different tumor types such as; ependymoma, medulloblastoma, diffuse intrinsic pontine glioma (DIPG) and glioblastoma. It is now considered part of the treatment armamentarium for these patients. The challenges and clinical results in treating recurrent pediatric brain tumors were highly documented.
DISCOVERY OF AN EXTRAORDINARY NUMBER OF RED SUPERGIANTS IN THE INNER GALAXY

In this Letter, we present a search for Galactic red supergiant stars (RSGs) in the direction of the inner Galaxy. A total of 94 targets selected from the 2MASS and GLIMPSE I North catalogs—via their blue extinction-free Q1 and Q2 colors—were spectroscopically observed at infrared wavelengths (in the H- and K-bands at R ∼ 1000), and an extraordinary high detection rate of RSGs ( > 61 % ) was found. We identified spectroscopically 58 RSGs, based on their flat continua and large equivalent widths of the CO-band at 2.293 μm (EW > 45 Å). This increase corresponds to about 25% of previously known RSGs in the Galactic region 10° < l < 60°, −1. °1 < b < 1. °1. In order to confirm the location of the new RSGs in the inner Galaxy, distances were estimated for a subsample of 47 stars with the clump method and found to range from 3.6 ± 0.4 to 8.6 ± 0.7 kpc. The large new sample will allow us to investigate Galactic metallicity gradients as a function of galactocentric distances and azimuthal angles. Such information is currently an highly disputed issue to constrain models of Galaxy formation and evolution.
DCR preferences among oculoplastic surgeons: Barriers and facilitators to adoption of endoscopic DCR

Objective To determine the preference for dacryocystorhinostomy (DCR), patient selection criteria for endoscopic DCR, endoscopic DCR technique, and barriers to adoption of endoscopic DCR. Method Cross-sectional study conducted from May-December 2021. A survey was sent to oculoplastic surgeons. Questions on demographic characteristics, type of clinical practice, technique preferences, barriers and facilitators to adoption of endoscopic DCR were included. Results 245 participants completed the survey. Most respondents were located at an urban site (84%), were in private practice (66%), and had been in practice for more than 10 years (58.9%). Sixty one percent perform external DCR as the first line procedure for treating primary nasolacrimal duct obstruction. The most common factor influencing the surgeon's decision to perform endoscopic DCR was the patient's request (37%) followed by endonasal exam (32%). The most common barrier for not performing endoscopic DCR was the lack of experience and lack of training during fellowship (42%). The most worrisome complication for most respondents was failure of the procedure (48%), followed by bleeding (30.3%). Eighty one percent believe surgical mentorship and supervision during initial cases would facilitate endoscopic DCR learning. Conclusions External Dacryocystorhinostomy is the preferred technique for treating primary acquired nasolacrimal duct obstruction. Learning endoscopic DCR early during fellowship training and high surgical volume to improve the learning curve dramatically impacts the adoption of the procedure.
Intimate Partner Violence and Children Under 5 Morbidities and Mortality in Afghanistan: Findings From a National Survey

Limited knowledge exists concerning the prevalence and drivers of intimate partner violence (IPV) against Afghan women and its association with child morbidity and mortality in Afghanistan. The study used data from the 2015 Afghanistan Demographic and Health Survey (ADHS 2015). The prevalence and associated sociodemographic factors of IPV were described by analyzing the data from Afghan women aged 15 to 49 years selected for the IPV module in ADHS 2015 (n = 24,070) whose children under 5 (n = 22,927) were included in the further analysis to estimate the morbidity and mortality of children and its association with IPV. It appeared that more than half of the Afghan women aged 15 to 49 years experienced IPV in the past year. Illiteracy (odds ratio [OR] = 1.69; 95% CI: 1.19, 2.39), living in rural areas (OR = 1.47; [1.19, 1.82]) being from the Pashtun, Tajik, Uzbek, and Pashai ethnic backgrounds were associated with a higher risk of IPV exposure. In general, the likelihood of child mortality within the first 5 years was higher among children born to mothers exposed to IPV, particularly physical and sexual even after adjustment for sociodemographic inequalities, the number of antenatal care, and marriage age. In addition, the odds of diarrhea, acute respiratory infection, and fever in the past 2 weeks were significantly higher among the children of victimized mothers in both adjusted and unadjusted models. Moreover, low birth weight and small birth size were more likely to be observed among the children of a mother who either experienced sexual or physical violence. The findings emphasized the elevated risk of morbidity and mortality among children under 5 born to mothers exposed to IPV and incorporating IPV screening into maternity and child care could reduce these adverse outcomes among Afghan women.
Model‐based estimation of the health care expenditure and out‐of‐pocket payment for assisted reproductive technology: A retrospective linkage study using the Japanese national ART registry

From April 2022, the Japanese government funding system for assisted reproductive technology (ART) has shifted from government subsidies to universal health insurance. To date, studies estimating the health care expenditure for ART are scarce. We estimated health care expenditures for ART cycles and compared the proportion of patients' out‐of‐pocket payment by ovarian stimulation protocols under the Japanese government subsidy system.