Miracle-dz/UniFAR-FTUs huggingface dataset:
A fresh approach for intercession of nonresponse in multivariate longitudinal designs

ABSTRACT The occurrence of nonresponse is very much plebeian in surveys, which troubles the analysis, and hence, an inappropriate inference is left out. To counterbalance the sour effects of the incompleteness, fresh imputation techniques have been proposed with the aid of multi-auxiliary variates for the estimation of population mean on successive waves. Properties of the proposed estimators have been elaborated, and they have been compared with the work of Priyanka et al. (2015). Detailed simulation study is carried out to substantiate the empirical and theoretical results. Several possible cases have been addressed in which nonresponse can occur.
In Vitro Characterization of chIFITMs of Aseel and Kadaknath Chicken Breeds against Newcastle Disease Virus Infection

Simple Summary Aseel and Kadaknath are indigenous chicken breeds in India. Due to their distinctiveness, these two breeds are becoming more important. Aseel has a reputation for cockfighting and having high-quality meat. The black flesh of Kadaknath is famous, and it is mostly raised for its meat and eggs. Both breeds have heat and disease tolerances. The chicken interferon-inducible transmembrane protein (chIFITM) genes function by preventing the entry of viruses into host cells, inhibiting viral replication, and controlling the viral load. This research was conducted to ascertain the level of chIFITM gene expression against the Newcastle disease virus (NDV) in chicken embryo fibroblast cells of both breeds. There are five members of the chIFITM gene family: chIFITM1, chIFITM2, chIFITM3, chIFITM5, and chIFITM10. chIFITM1, 2, and 3 have immune-related activity; as a result, these three are referred to as immune-related IFITM (IR-IFITM). All the chIFITM genes were shown to be highly expressed in the CEF cells of both breeds during our investigation. The Kadaknath CEF cells had a significantly low viral load and a high quantity of mRNAs for the chIFITM genes when the breeds were compared. Aseel cells demonstrated an earlier onset of NDV-induced cytopathic changes compared to Kadaknath. Abstract Newcastle disease (ND) is highly contagious and usually causes severe illness that affects Aves all over the world, including domestic poultry. Depending on the virus’s virulence, it can impact the nervous, respiratory, and digestive systems and cause up to 100% mortality. The chIFITM genes are activated in response to viral infection. The current study was conducted to quantify the mRNA of chIFITM genes in vitro in response to ND viral infection. It also examined its ability to inhibit ND virus replication in chicken embryo fibroblast (CEF) cells of the Aseel and Kadaknath breeds. Results from the study showed that the expression of all chIFITM genes was significantly upregulated throughout the period in the infected CEF cells of both breeds compared to uninfected CEF cells. In CEF cells of the Kadaknath breed, elevated levels of expression of the chIFITM3 gene dramatically reduced ND viral growth, and the viral load was 60% lower than in CEF cells of the Aseel breed. The expression level of the chIFITMs in Kadaknath ranged from 2.39 to 11.68 log2 folds higher than that of control CEFs and was consistently (p < 0.01) higher than Aseel CEFs. Similar to this, theIFN-γ gene expresses strongly quickly and peaks at 13.9 log2 fold at 48 hpi. Based on these cellular experiments, the Kadaknath breed exhibits the potential for greater disease tolerance than Aseel. However, to gain a comprehensive understanding of disease resistance mechanisms in chickens, further research involving in vivo investigations is crucial.
Association of Soluble Markers of Inflammation With Peri-coronary Artery Inflammation in People With and Without HIV Infection and Without Cardiovascular Disease

Abstract Background Inflammation is linked to elevated cardiovascular disease (CVD) risk in people with HIV (PWH) on antiretroviral therapy (ART). Fat attenuation index (FAI) is a measure of peri-coronary inflammation that independently predicts CVD risk in HIV-uninfected persons. Whether FAI is associated with soluble inflammatory markers is unknown. Methods Plasma levels of inflammatory markers were measured in 58 PWH and 16 controls without current symptoms or prior known CVD who underwent coronary computed tomography angiography and had FAI measurements. A cross-sectional analysis was performed, and associations of markers with FAI values of the right coronary artery (RCA) and left anterior descending artery (LAD) were assessed using multivariable regression models adjusted for the potential confounders age, sex, race, low-density lipoprotein cholesterol, body mass index, and use of lipid-lowering medication. Results Several inflammatory markers had significant associations with RCA or LAD FAI in adjusted models, including sCD14, sCD163, TNFR-I, and TNFR-II, CCL5, CX3CL1, IP-10. Conclusions The associations between indices of systemic and peri-coronary inflammation are novel and suggest that these systemic markers and FAI together are promising noninvasive biomarkers that can be applied to assess asymptomatic CVD in people with and without HIV; they also may be useful tools to evaluate effects of anti-inflammatory interventions.
Recent Results From MINOS

The MINOS experiment (Main Injector Neutrino Oscillation Search) uses two detectors sep-arated from 735 km to measure the oscillation parameters of the beam of muon neutrinos produced by the NuMI facility. Neutrino oscillations are observed by comparing the observed energy spectrum at the Far Detector, in Northern Minnesota, with the expectation extrapo-lated from the measured spectrum at the Near Detector at Fermilab. This paper describes four results from the ﬁrst three years of operation. Firstly, the observation of muon neutrino disappearance that gives the best measurement of ∆ m 223 to date. Secondly, the result from the 7% component of muon antineutrinos in the beam that allows us to study, for the ﬁrst time in a long-baseline accelerator experiment, antineutrino oscillations and set a limit on their oscillation parameters. Thirdly, the search for electron neutrino appearance that sets a limit on the mixing angle sin 2 (2 θ 13 ). Finally, the analysis of the neutral current energy spectrum that produces an upper limit on the fraction of sterile neutrinos mixing with muon neutrinos.
Promoting Sustainable Tourist Behavior through Promotional Marketing

This study aims to investigate the current state of Bhaktapur, Nepal, as a tourist destination and how promotional marketing strategies can be used to increase the number of tourists visiting the area. The research uses the AIDA model to analyze Bhaktapur's promotional marketing as a tourist destination. 282 tourists were surveyed through the Kobo Toolbox app to gather information about their demographics and travel profiles. The data was analyzed using SPSS and SEM to find variations in groups and predict the impact of promotional marketing on sustainable tourism demand in Bhaktapur. The findings indicate that utilizing a range of promotional marketing strategies, such as social media, and targeting different demographic groups can be effective in attracting tourists and highlight the significance of tourism as a key source of foreign exchange revenue for Nepal and suggests that promoting Bhaktapur as a tourist destination can contribute to the country's economic growth. This study contributes to the rising interest in determining the Internet's significance as a commercial tool in the tourist industry. Internet is currently the primary method for hotels and other service-based enterprises to communicate with their clients. Thus, this study aims to fill a vacuum in the literature by demonstrating how to leverage the Internet and social media as part of a marketing strategy to build a sustained demand among visitors concerned with social concerns and the environment.
Estimation and Inference of Linear Trend Slope Ratios With an Application to Global Temperature Data

We examine estimation and inference of the ratio of linear trend slopes between two time series. Our methodological results are motivated by recent empirical climate papers that estimate and test hypotheses about the relative warming rate in the lower‐troposphere relative to surface warming, i.e. the amplification ratio. We analyze statistical properties of several estimators and test statistics that allow serial correlation. Relative merits of the estimators and test statistics depend on the magnitude of the trend slopes relative to the noise in the data. We make specific recommendations for practitioners. We revisit the empirical findings of Klotzbach et al. (2009, 2010) and obtain similar results using our recommended approach.
Computations of heave added mass and damping coefficients of some rigid bodies using WAMIT

The heave added mass and damping coeﬃcients of some rigid bodies are computed using the three-dimensional radiation/diﬀraction code WAMIT [5], which is based on the boundary element method. The higher-order panel method is used, whereby the velocity potential on the body is represented by B-splines in a continuous manner. In most ap-plications, this provides a more accurate solution compared to the low-order method, whereby the geometry of the body is represented by an ensemble of ﬂat quadrilateral panels, and the velocity potentials are approximated by piece-wise constant values on each panel. The panel models are prepared using the CAD program MultiSurf [4]. The geometry is imported directly from MultiSurf into WAMIT by linking to the MultiSurf kernel during execution of WAMIT. The link between WAMIT and MultiSurf allows the user to override ﬂoating-point values in the deﬁnition of any entity in the model. This allows a single model (parametrically constructed) to be analysed in a wide variety of conﬁgurations without opening the model and making any changes in MultiSurf. The option to remove the eﬀects of irregular frequencies is used. Also, co-sine spacing is used to provide better resolution in regions with high gradients. Patches are automatically subdivided into panels such that the maximum length of each panel is approximately equal to a speciﬁed parameter. By decreasing this parameter, systematic convergence tests can be made easily without changing any other parameters or inputs.
Comparison of laboratory parameters of a mountain bike specific performance test and a simulated race performance in the field

Previous studies have described the need for a tailored performance test to predict mountain bike performance. This test should improve characterisation of intensive and intermittent physiological demands of mountain biking. Therefore, the aim of the study was to identify mountain bike related parameters that can more accurately explain the variance of mountain bike performance. Ten competitive mountain bike riders (age: 34 Â± 8.7 years; VI‡O 2 peak: 69 Â± 11.1 mlÂ·min âˆ’1 Â·kg âˆ’1 ) participated in the following tests: (a) an incremental bicycle ergometer test to determine their individual anaerobic threshold (IAT) and maximal oxygen consumption (VI‡O 2 peak), (b) an isometric strength test, (c) a second bicycle ergometer test consisting of time trials with maximal effort during 10-s, 1-min and 5-min trials and (d) a simulated race in the field. The laboratory parameters were scaled by body weight and subsequently compared with the mean power scaled by body weight and the race time using univariate correlations ( r power ; r time ) . The incremental test parameters of individual anaerobic threshold ( r power = 0.70; r time = âˆ’0.74) and VI‡O 2 peak ( r power = 0.85; r time = âˆ’0.86) showed strong correlations with the mean power output during the race and the race time. This result also applies for PO of the laboratory time trials during 1 min ( r power = 0.69; r time = âˆ’0.68) and 5 min ( r power = 0.63; r time = âˆ’0.82). PO of the 10-s time trial ( r power = 0.20; r time = âˆ’ 0.44), as well as maximal muscle strength ( r power = âˆ’0.13; r time = âˆ’0.24), were weakly correlated. In conclusion, power outputs of the 1- and 5-min time trials showed similar correlations with race performance compared with traditional aerobic parameters. These findings underline that traditional aerobic parameters of an incremental test, as well as power output during short high intensive intervals, should be considered when analysing mountain bike performance. Â
Risk Management in Private Companies and Public Sector Organizations: A Preliminary Comparative Study

Purpose – The effectiveness of risk management in an organization depends largely on its organizational culture as revealed in its governance structure and organizational process. The research question of this study is how to develop strategy to improve the effectiveness of risk management under the constraints of a given organizational culture. The objective of this study is to show that there are fundamental differences and similarities between the governance structure and organizational process that significantly influence the effectiveness of risk management in private companies and the one in public sector organizations. Methodology – To achieve the objective, legal documents of major public and private organizations are reviewed and key resource persons working for the organizations are interviewed. Findings – This paper reports preliminary results that identify several important dimensions of governance structure and organizational process in both sectors that crucially influence the effectiveness of risk management. Originality – Studies on the similarities and differences between public and private organizations in implementing risk management have been very rare. Very few studies explicitly address the effectiveness of risk management in the perspective of the comparative study. This study has never been carried out before, at least in the Indonesian context.
Periodontitis Severity Grading Scale and C-Reactive Protein: A Possible Relation

Background C-reactive protein (CRP) is the first acute-phase protein and is an exceptional investigative marker for local and systemic inflammation. The periodontitis severity grading scale (PSGS) indicates the extent of periodontal inflammation. Therefore, the aim of the study was to explore the correlation between the markers of systemic and periodontal inflammation as assessed by CRP and the PSGS in participants with periodontitis. Materials and methods The present study enrolled 85 systemically healthy participants with periodontitis. PSGS and CRP levels were measured in each participant. Descriptive and inferential statistics were applied for analysis. Results The PSGS scores ranged from 24 to 213, and the CRP levels ranged from 0.5 to 3.23 mg/l. This shows a positive correlation between the periodontal scale and CRP. A nonsignificant (p-value > 0.05) correlation exists between age and CRP score, and a significant association was seen between gender and severity of periodontitis with p-value < 0.02. A highly significant association between gender and CRP score was found with p-value < 0.001. Conclusion The level of serum CRP dramatically increased with the severity of periodontitis. The results of this study point to a highly significant correlation between markers of systemic and periodontal inflammation, as well as a strength of association between the two markers.
Wideband and high efficiency reflective polarization rotator based on metasurface

Abstract A wideband and high efficiency reflective polarization rotator (PR) based on metasurface is presented. The unit cell of the PR consisting of two oblique symmetry triangle split rings and simulated results show the PR has more than 90% polarization conversion efficiency from 9.24 to 17.64 GHz (a relative bandwidth of 62.50%) under normal incidence. The broad polarization conversion bandwidth and high efficiency results from multiple plasmon resonances and nearly 100% polarization conversion is obtained at three plasmon resonances. The mechanism of the proposed PR is analyzed by surface current distributions. Electric and magnetic resonances generate broad polarization conversion bandwidth and high polarization conversion ratio within the operating band. In addition, we analyze the polarization states of the PR unit numerically based on the reflected fields, which serves as theoretical predictions of polarization conversion. To verify the simulation results and analysis, a sample was fabricated and measured. The measured results are in good agreement with simulated results and numerical analysis.
Wild Vitex agnus-castus L.: Phytochemical Characterization, Acute Toxicity, and Bioactive Properties

Wild Vitex agnus-castus (VAC) is a Mediterranean plant that is rich in bioactive metabolites. This study aimed to validate, for the first time, the beneficial use of VAC fruits and fruit decoctions (VFDs) through in vitro and in vivo trials. Forty-one volatile components were detected in VAC fruits, with 1,8-cineole (30.3%) comprising the majority. The antioxidant activity of VFD was measured by using different in vitro methods (EC50 of 0.16 mg/mL by β-carotene bleaching inhibition assay) and by measuring the DNA protection power. Using the disc diffusion assay, the antimicrobial activity of VFD was evaluated, and it exhibited a noticeable anticandidal activity. VFD did not cause any toxicity or mortality in rats treated with doses > 200 mg/kg. Using the acetic acid writhing test, the antinociceptive activity of VFD was measured. Our results showed that VFD at 200 mg/kg exhibited a higher analgesic activity (81.68%) than acetylsalicylic acid used as a positive control (74.35%). Its gastroprotective ability was assessed by HCl/ethanol-induced gastric lesions, which were remarkably inhibited (84.62%) by intraperitoneal administration of VFD. This work helps to validate the popular use of VAC to treat nociceptive, inflammatory, and gastric disorders and encourages researchers to further investigate the identification of pharmacological compounds from this species.
Using Edutainments in Teaching Orthodontic Lateral Cephalometric and Dental Cast Analysis

Background: Many educators have developed an interest in an emerging new concept called entertainment education (edutainment). Edutainment is a kind of tool that, in this age of technology, can be easily incorporated into education. Objectives: This study aimed to use edutainment for teaching orthodontic lateral cephalometric and dental cast analysis as well as to evaluate the dental students’ attitudes towards it. Methods: In this cross-sectional study, the multimedia-enhanced with edutainment was designed using Articulate Storyline version 3.5. To evaluate the students’ attitudes, 52 ninth-semester dental students doing their second semester in 2019 - 2020 were included in the study. Then they were asked to complete a standard questionnaire with a 7-point Likert scale from strongly disagree to strongly agree and including 26 items in eight domains of perceived self-efficacy, perceived satisfaction, understanding usefulness, behavioral concept, e-learning system quality, interactive learning activities, e-learning effectiveness, and multimedia instructions. Data were analyzed and expressed using independent sample t-test, one-way ANOVA, and descriptive statistics. Results: The majority of the students had positive attitudes towards the areas of perceived self-efficacy (83.3%), perceived satisfaction (90.4%), perceived usefulness (96.8%), behavioral intention (91.7%), e-learning system quality (75%), interactive learning activities (73.1%), e-learning effectiveness (88.5%), and multimedia education (85.3%). Conclusions: In sum, the students’ attitudes towards learning were positively and significantly influenced by the designed educational multimedia enhanced with edutainments to teach lateral cephalometric analysis in orthodontics. It was found that the application of edutainment as an educational tool together with traditional training may have been an effective method for teaching and, therefore, it was recommended that edutainment should be used as an alternative to traditional methods during crises such as the COVID-19 pandemic.
Perceived Organizational Support and Pedagogical Content Knowledge of TLE Teachers; the Mediating Role of Program Resources

This study determined the mediating effect of program resources on perceived organizational support and pedagogical content knowledge of TLE teachers. Quantitative descriptive correlational design was employed. The study was conducted through online survey in a public school of Division of Davao del Sur during the school year 2021-2022. The TLE public junior high school teachers who are the respondents were chosen using purposive sampling. Data utilized in this study were gathered through adopted questionnaires. Mean, Pearson product-moment correlation and path analysis were among the statistical tools used. Results revealed that TLE teachers had a very high level of perceived organizational support, a very high level of pedagogical content knowledge, and a high level of program resources. Moreover, there is a significant relationship among perceived organization support of TLE teachers and their pedagogical content knowledge, perceived organization support and program resources, and program resources and pedagogical content knowledge. It was also revealed that the program resources partially mediated the relationship between perceived organizational support and pedagogical content knowledge. With considerations on the findings of the study, the perceived organization support of TLE teachers was evident at all times. Second, the pedagogical content knowledge as perceived by TLE teachers was important all the time. Lastly, the program resources were evident most of the time. It was recommended that the school administrators should support the improvement of program resources in schools.
Non-Hermitian Chern bands and Chern numbers

The relation between chiral edge modes and bulk Chern number is a paradigmatic example of bulk-boundary correspondence. We show that in the presence of non-Hermiticity, the Chern number defined by the Bloch Hamiltonian is not strictly tied to the chiral edge modes. We introduce a non-Bloch Chern number for non-Hermitian Chern bands, which faithfully counts the chiral edge modes. The theory is backed up by the open-boundary energy spectra and dynamics of a concrete lattice model, whose phase diagram is found to be consistent with the theoretical prediction. Our results highlight a unique and essential feature of non-Hermitian bands.
Maternal Exposure to Potentially Toxic Metals and Birth Weight: Preliminary Results from the DSAN-12M Birth Cohort in the Recôncavo Baiano, Brazil

Prenatal exposure to potentially toxic metals (PTM) may impair fetal growth (FG). We investigated the relationship between maternal exposure to lead (Pb), cadmium (Cd) and manganese (Mn) and birth weight (BW) of 74 newborns. Blood was collected during the second trimester of pregnancy to determine Pb (PbB) and Cd (CdB), while hair (MnH) and toenails (MnTn) were used for Mn. Samples were analyzed by graphite furnace atomic absorption spectrophotometry (GFAAS). Sociodemographic and BW data were collected from questionnaires and maternity records, respectively. The medians (P25th–P75th) of PbB, CdB, MnH, and MnTn were, respectively, 0.9 (0.5–1.8) µg/dL; 0.54 (0.1–0.8) µg/L; 0.18 (0.1–0.4) µg/g; and 0.65 (0.37–1.22) µg/g. The means (standard deviation) of birth weight according to sex were 3067 (426.3) and 3442 (431) grams, respectively, for girls and boys. MnTn presented an inverse correlation with the BW/gestational age ratio for girls (rho = −0.478; p = 0.018), suggesting the effect of sex modification. Although BW correlation with CdB was not statistically significant, hierarchical linear regression (beta = −2.08; 95% CI–4.58 to 0.41) suggested a fetotoxic effect. These results confirmed the threat PTMs may represent and the need for more extensive research to elucidate their role in inadequate FG in developing countries.