Miracle-dz/UniFAR-FTUs huggingface dataset:
Effect of probiotics and Yucca schidigera extract supplementation on broiler meat quality

The current study investigated the effect of dietary supplementation with probiotics and Yucca schidigera extract on physicochemical parameters, proximate composition, mineral content and fatty acid profile of broiler breast and thigh muscles. In total, 240 one-day old broilers were randomly allocated into two dietary treatments groups: 1) Control (basal diet), 2) experimental (basal diet with two probiotics Pediococcus acidilactici and Saccharomyces cerevisiae and Yucca schidigera extract). The results showed that the pH value was higher in the experimental group than in the control group (p < 0.05). However, drip, cook and thaw losses were not influenced by dietary treatment (p > 0.05). A significant increase in protein, Fe, Zn, Na, P and a significant decrease in lipid, Cu and Cr contents was exhibited in experimental group relative to control group (p < 0.05). The proportion of stearic acid and saturated fatty acids was significantly (p < 0.05) reduced, whereas linoleic acid and polyunsaturated fatty acids contents were significantly (p < 0.05) increased in breast and thigh muscles of fed the experimental diet. We concluded that additive supplementation of the diet with probiotics and Yucca schidigera extract could improve meat quality.
MicroRNA-107 promotes apoptosis of acute myelocytic leukemia cells by targeting RAD51

Introduction This study aimed to investigate the role of microRNA (miRNA) that affects acute myelocytic leukemia (AML) and its potential molecular mechanism by constructing a miRNA–mRNA interaction network using bioinformatics methods. Material and methods MicroRNA expression data of AML were retrieved from Gene Expression Omnibus (GEO) and analyzed by microarray analysis. Expression levels of miR-107 and RAD51 mRNA were detected by quantitative real time polymerase chain reaction (qRT-PCR). Protein expression of RAD51, pro-apoptotic protein Bax, apoptosis related protein CytC and anti-apoptotic protein Bcl-2 were determined by Western blot. The rate of cell apoptosis was detected by Annexin-V/PI. The predicted targeting relationship between miR-107 and the 3′UTR of RAD51 was first predicted by the online application TargetScan and then verified by dual-luciferase assay. Results Acute myelocytic leukemia-associated genes (n = 197) and miRNAs (n = 1701) were retrieved from the database, the interaction network of miRNA-mRNA was constructed and the core position was occupied by RAD51. miR-107 exhibited a regulatory effect on RAD51 in which the mRNA and protein expression of RAD51 were both significantly inhibited by miR-107 mimics in vitro. Additionally, down-regulated expression of miR107 as well as up-regulated expression of RAD51 were detected not only in the plasma of AML patients compared to healthy volunteers, but also in AML cell lines compared to the normal bone marrow stromal cell line. Further study found that increased expression of miR-107 and the consequent down-regulation of RAD51 could aggravate the apoptosis of AML cells in vitro. Conclusions Our present results showed that the crucial role of RAD51 and miR-107 in the apoptosis of AML cells, i.e., miR-107 promotes the apoptosis of AML cells through down-regulating the expression of RAD51.
CHEMICAL COMPOSITION OF BUFFALO’S RAW MILK AND ITS RURAL PRODUCTS IN SOME VILLAGES IN SOHAG GOVERNORATE

A lot of 180 samples of fresh buffalo’s raw milk, and its rural milk products (laban rayeb, Samna, cream, Kareish cheese, and Mish cheese) were collected from 10 villages from Sohag Governorate). These samples were applied for chemical analysis (pH value, Total Solids, Ash, Total protein and Fat). It was found that the average contents were 6.73, 15.79%, 0.75%, 3.99 % and 6,71 % respectively for Buffalo’s milk; 4.63, 11.53%, 0.67%, 4.68% and 2.23% respectively for Laban rayeb; 5.11, 53.5%, 0.52%, 3.04% and 31.4% respectively for Cream; 4.33, 98.61%, 0.05%, 0.19% and 98.38% respectively for Samna; 4.32, 26.56%, 3.02%, 15.31% and 4.24% respectively for Kareish cheese, and were 4.41, 38.8%, 11.37%, 18.51% and 4.9% respectively for Mish cheese. In the cases of Kareish and Mish cheese the cheeses, average of salt content were 7.1 and 15.39 respectively. Statistical analysis showed that there were highly significant variations among products of the different villages. These variations may be attributed the different behavior of farmers through the milking and manufacture processes of these products.
Bacterial and clinical assessment of two different designs tooth supported overdenture

This study compared the bacteriological effect and clinical finding of two different designs of abutments in tooth supported over denture.Materials and Methods: Twenty male completely edentulous patients were selected and randomly divided into two equal groups according to the abutments design. Group 1: Patients were rehabilitated with complete over denture supported by two dome shaped endodontically treated teeth with composite plug. And Group 2: Patients were rehabilitated with complete over denture supported by two dome shaped Endodontically treated teeth with zirconium post and coping. The Microbiological swabs were collected from buccal, lingual, mesial and distal surfaces of the abutment for each patient in order to evaluate the bacterial colonization. On other hand, the clinical assessment was done including pocket depth evaluation. at the time of insertion, 3, 6, 9 and 12 months after over denture insertion. The data were collected and statistically analyzed. Results: The quantitative bacterial culture from each group of patients ( n=10) had revealed statistical significant increase the percentage of bacterial count in (group I) of patients that were wearing over dentures without coping compared to the other group of patients (group II) that were wearing over dentures with zirconium coping with statistical significant difference( p<.0.001<.0.001) and regarding the clinical assessment there was no statistical significant difference between two groups . Conclusion: Abutments supported over denture with zirconium copings as regard to bacterial and clinical assessment are much better for oral hygiene maintenance than abutments without copings. Further studies are recommended by other experimental means like Electron Microscopy, other bacterial species to support this research.
Using A Group Support System in Strategic Academic Planning – A Field Experimental Study on the Influence of Facilitation

This paper presents the results from a field experimental study on the role of facilitation for improving the quality of ideas generated in a GSS environment used for strategic planning within an academic department. The content of the ideas on academic management generated as part of the planning work is not discussed as it is specific for the particular department. Instead we focus here on process facilitation in group decision making and the role of the facilitator. The contributions of the paper are in the originality of the application area (academic strategic management) chosen for the use of a GSS and in the insights from the field experimental study on the effect of facilitation on the quality of the work of the participating lecturers from a university computing department who had real vested interest in the problem of concern
“Why Does a Teacher Feel the Need to Post My Kid?”: Parents and Teachers Constructing Morally Acceptable Boundaries of Children’s Social Media Presence

Posting about children on social media is common practice today, with adults acting as agents who make choices about these digital representations. This study focuses on the management of children’s online presence as debated in an online parenting forum by thematically analyzing 556 posts from 13 discussion threads about daycare and elementary school teachers sharing pictures of their students online. Findings show how this event is framed as a boundary crossing undermining parents’ ability to steward their children’s digital footprints. Furthermore, posters stress the risks associated with such photo-sharing behavior, construct moral identities creating the roles of the good or bad parent and teacher in a social media age, and propose solutions to regain control and restore parental agency. These findings suggest that this occurs to affirm the family as a higher-level system when it comes to setting boundaries about children’s social media presence.
Polyvinyl alcohol/CuO nanocomposite hydrogels: facile synthesis and long-term stability

Within this study, Polyvinyl alcohol/CuO nanocomposite hydrogels were synthesized through dispersing CuO nanoparticles in a PVA solution, using the freeze-thawing procedure in order for physically crosslinking. The average particle size of CuO nanoparticles which was added to the hydrogel was determined as 3.51 nm according to the XRD analysis after the ball milling process. The presence of CuO nanoparticles in nanocomposite hydrogels was determined by UV-vis spectroscopy, FESEM, EDS, and FTIR analysis. Also, the rheological properties of neat hydrogel and PVA/CuO nanocomposite hydrogels were examined. The addition of CuO nanoparticles to the polymer structure develops rheological features of PVA hydrogels. The Effect of CuO content of nanocomposite hydrogels on the swelling behavior and long term stability was investigated. These nanocomposite hydrogels demonstrated unique properties for biomedical applications due to their high swellability at pH 2.1 as the pH values of the stomach and long term stability. According to these results, the addition of CuO to the hydrogel structure improved the swelling characteristics of neat PVA hydrogel.
Foreign direct investment and economic growth: the role of democracy

This study investigates the growth-effect of foreign direct investment (FDI) in 67 developing countries covering from 1984 to 2016, with a special emphasis on the role of democracy. The empirical results obtained from generalized method of moments (GMM) estimation demonstrate that democracy plays a crucial role in moderating the positive effect of FDI on output growth. The results are robust to several alternative measures of democracy and FDI. This suggests that the marginal effect of FDI on growth depends on the level of democracy such that countries which promote democratic institution benefit more from FDI inflows. The finding is consistent with the growing view that the growth-effect of FDI depends on other intervening factors in the host countries.
The influence of website quality on consumer’s e-loyalty through the mediating role of e-trust and e-satisfaction: An evidence from online shopping in Vietnam

The aim of the present study is to examine the influence of website quality on consumer’s e-loyalty, noting the mediating role of e-trust, e-satisfaction, and perceived enjoyment. Besides, this study examines the consequence of consumer’s e-loyalty. Survey data collected from 594 respondents aged at least 16 years and performed some online shopping through websites in Vietnam. Based on the theoretical framework, PLS-SEM using SmartPLS 3.0 software was deployed to discover links between the constructs. The results showed a positive effect of website quality on e-loyalty, which was mediated partially through consumer e-trust and e-satisfaction. Moreover, e-loyalty had a positive association with electronic word of mouth (eWOM) as well. The main findings of this research provide some empirical implications for Internet marketers and online retailers in Vietnam. E-vendors should understand the customers’ expectations and e-loyalty regarding online shopping to attract new customers as well as to retain their existing customers.
Volatile production differs between oak leaves infested by leaf-miner Phyllonorycter harrisella (Lepidoptera: Gracillariidae) and galler Neuroterus quercusbaccarum (Hymenoptera: Cynipidae)

Plants defend themselves by producing various volatile organic compounds (VOCs) that have direct and indirect effects on insect herbivores. Their production is often specific to the plant and herbivore species involved, with some herbivores being able to manipulate their production. Here, we used passive volatile sampling using polydimethysiloxane (PDMS) tubing to compare VOCs produced by control, mined and galled oak leaves in the field. Leaves mined by a microlepidopteran leaf-miner (Phyllonorycter harrisella) produced a lower amount of two sesquiterpenes and an increased amount of eucalyptol. In contrast, leaves galled by the gall wasp (Neuroterus quercusbaccarum) did not produce a lower amount of any of the VOC measured when compared to the control. They produced a higher amount of farnesene, β-bourbonene and eucalyptol. Some of these VOC are known for their anti-herbivore function. In a second experiment, we treated the experimental leaves with the phytohormone methyl jasmonate (MeJA) to determine if leaf-miners or gallers reduced the overall inducibility of infested leaves. MeJA induced a sixteen-fold increase in VOC production. However, there was no difference in VOC production of control, mined and galled leaves treated with MeJA. Our results show that up- and down-regulation of VOCs can vary among leaves infested by different herbivores. More experiments are needed to determine if this is due to manipulation by the herbivores themselves or due to a defensive response of the plant.
Knowledge and practices among male medical students regarding smoking and its hazards

Background: Tobacco use is the leading preventable cause of death worldwide, and according to the latest estimates, by year 2030, 10 million annual tobacco-attributable deaths worldwide, 70% of which will be in low-middle-income countries. The purpose of study was too assess the knowledge and practices regarding cigarette smoking among male medical students in Allama Iqbal Medical College, Lahore, Pakistan and to assess the awareness of students regarding smoking related health hazards. Methods: A Cross-Sectional Study was conducted From May 2009 - September 2009 in Allama Iqbal Medical College, Lahore, Pakistan. The male students enrolled in Allama Iqbal Medical College Lahore, were selected by non-probability convenient sampling. Results: In present study 47.3% respondents were smokers, 94.1% were knowledgeable about hazards of smoking, 85.9% were aware about passive smoking, and 19.1% started consuming tobacco below 17 years of age. Only 19.1% tried to quit smoking but none of them succeeded. 25% have no family association of smoking. There were 18.2% who’s mostly close friends were smokers only 13.2% smokes more than 15 cigarettes daily. 43.6% said they would smoke cigarette if one of their close friends offer them. 30.5% believe cigarette smoking help to relax and 25% want to quit smoking among them 10% want to quit due to its hazards while 5.9% due to family pressure. Conclusions: Present study concluded that high proportion male medical students smoke cigarette. Most of them were unaware about tobacco consumption hazards, and passive smoking.
Intelligence, Errors and Strategic Choices in the Repeated Prisoners' Dilemma

A large literature in behavioral economics has emphasized in the last decades the role of individual differences in social preferences (such as trust and altruism) in influencing behavior in strategic environments. Here we emphasize the role of attention and working memory, and show that social interactions among heterogeneous groups are mediated by differences in cognitive skills. Our design uses a repeated prisoner’s dilemma; we compare rates of cooperation in groups of subjects separated according to their IQ, with those in integrated groups, where subjects of different IQ are pooled together. In integrated groups we observe higher aggregated cooperation rates and profits than in separated groups. There are gains in earnings among lower IQ subjects who learn how to cooperate faster than when they play separately, and smaller losses for higher IQ subjects. We also see that higher IQ subjects become less lenient when they are matched with lower IQ subjects than when they play separately. This pattern is an instance of a general phenomenon, which we demonstrate in an evolutionary game theory model, in which higher IQ among subjects induces –possibly thanks to better working memory– a lower frequency of errors in strategy implementation. We show that players indeed choose less-lenient strategies in environments in which subjects have higher error rates. Estimations of errors and strategies from the experimental data are consistent with the hypothesis and model’s predictions.
In vitro ruminal degradation of carbohydrate fractions in tropical grasses fertilized with nitrogen

The goal was to determine the digestion rates of carbohydrate fractions A (sugars, oligosaccharides and organic acids), B1 (starch and soluble fiber), NSC (non-structural carbohydrates) and B2 (available NDF) in four tropical grasses using the gas production technique. Samples of whole forage (WF), residue insoluble in 90% ethanol (EIR) and isolated NDF (iNDF) were fermented in vitro and gas production measured. Gas volumes were determined from the following fractions, A = WF minus EIR; B1 = EIR - ND; NSC = WF - iNDF; and B2 = iNDF. Grasses were Andropogon gayanus, Urochloa brizantha, Cynodon plectostachyus, and Megathyrsus maximus each grown in Veracruz, Mexico on four plots (5×5 m), fertilized (relationship equivalent to 0 and 100 kg N/ha) and clipped 35 d after the N fertilization. A complete randomized block design with factorial arrangement 4×2 and two replicates per treatment was used. Factors were grass species and N fertilization. Data were fit using a single-pool exponential model with lag. The volume (mL gas/100 mg OM), rate (%/h) and lag (h) were: WF (22.8; 5.3; 2.1); A (3.2; 15.7; 0.5); B1 (1.5; 15.7; 0.2); and B2 (18.3; 6.6; 5.2). Andropogon and Urochloa had higher NSC content compared to Megathyrsus and Cynodon but lower gas yield per unit of NSC. Rates of digestion for the B2 fraction ranged from 4 to 8 %/h; and NSC digestion rate averaged 15.7 %/h. Nitrogen fertilization reduced carbohydrate pool sizes but did not affect rates of digestion. It is concluded that the rates of digestion of the carbohydrate fractions differs by grass specie.
UV Phototherapy: A New Look at the UV Sources and Doses

Ultraviolet (UV) lamps are widely used in phototherapy, especially for the treatment of skin diseases. Although the positive effect of UV radiation is mainly associated with the synthesis of vitamin D in human skin, nevertheless, to avoid negative consequences, the determination of radiation doses is based on the erythemal activity of UV sources, and, as a rule, the initial doses are 0.5 1 MED. Moreover, although broadband UV lamps are known to be more productive for the vitamin D synthesis, narrowband UV sources are preferred to minimize the negative effect of UV radiation on DNA. To find the missing link between the erythemal and ‘antirachitic’ UV doses we performed direct measurements of the erythemal activity and the vitamin D synthetic capacity of the two most used UV lamps broadband TL12 and narrowband TL01 (Philips). Erythemal doses were calculated from the spectroradiometer data, and antirachitic activity was measured using an original method based on the in vitro model of vitamin D synthesis. As expected, with an erythema dose of 1 SED (100 J/m2), the amount of direct precursor of vitamin D formed under the TL12 lamp was significantly higher than under the TL01 lamp. Thus, if the UV therapeutic effect is associated with the synthesis of vitamin D, then the time of UV irradiation with the TL12 lamp can be significantly reduced. These results show the feasibility of revising the conventional recommendations on UV light sources and doses in order to reduce negative UV effects.
INVESTIGATIVE ANALYSIS OF LARGE TRUCK ACCIDENT CAUSATION A. James McKnight The TRB Committee for Review of the FMCA Truck Crash Causation Study

The cost in damage, injury, and life resulting from accidents has focused great attention within government, industry and the public on means of preventing their occurrence and reducing their consequences. One logical step in accident prevention is discovering what causes them. The FMCSA Large Truck Crash Causation Study (LTCCS) represents just such an effort. Gathering information on 1,000 crashes involving large trucks is expected to yield information that can be applied to accident prevention.
The implications of novel oral anticoagulation in ocular surgery

Anticoagulation drugs play a significant role in modern day surgeryto treat and prevent thromboembolic disease. Warfarin is one of the commonest anti-coagulation used. The dosing of warfarin can be accurately managed by checking international normalized ratio (INR). It is of vital importance when any surgery is planned for a patient so that the dose of warfarin can be adjusted to decrease complication related with bleeding. The advent of new oral anticoagulation therapy with improved safety profile has improved clinical outcomes. However it’s difficult to adjust the dosing of oral anticoagulants for any surgery due to lack of monitoring test like INR and subsequently difficult to reverse their anti-coagulant effect. Anti-coagulation needs to be very closely monitored and dose adjusted to avoid any complications of intra-ocular surgery. The clinician’s ability to understand appropriate dose management and follow-up decisions will have a deep impact, if such decisions are wrong. There is limited evidence and guideline for use and adjusting the dosage of newer anti-coagulant for intraocular surgery. The aim of this study is to provide evidence-based guidelines for the management of patients receiving novel oral anticoagulant therapy in Ophthalmology practice. A reproducible framework has been created with this guideline that may provide a process to synchronize outpatient anticoagulation supervision. This guideline aims to provide a practical, clinician focused approach to periprocedural anticoagulant management, which is valuable to both ophthalmologists and anesthetists who play a major part in providing local blocks and sedation, monitoring patients and managing life threatening conditions, should the need arise.
Vitamin D Deficiency Aggravates Hepatic Oxidative Stress and Inflammation during Chronic Alcohol-Induced Liver Injury in Mice

Vitamin D deficiency has been reported in alcoholics. This study is aimed at evaluating the effects of vitamin D deficiency on chronic alcohol-induced liver injury in mice. Mice were fed with modified Lieber-DeCarli liquid diets for 6 weeks to establish an animal model of chronic alcohol-induced liver injury. In the VDD+EtOH group, mice were fed with modified diets, in which vitamin D was depleted. Vitamin D deficiency aggravated alcohol-induced liver injury. Furthermore, vitamin D deficiency aggravated hepatocyte apoptosis during alcohol-induced liver injury. Although it has a little effect on hepatic TG content, vitamin D deficiency promoted alcohol-induced hepatic GSH depletion and lipid peroxidation. Further analysis showed that vitamin D deficiency further increased alcohol-induced upregulation of hepatic inducible nitric oxide synthase (inos), two NADPH oxidase subunits p47phox and gp91phox, and heme oxygenase- (HO-) 1. By contrast, vitamin D deficiency attenuated alcohol-induced upregulation of hepatic antioxidant enzyme genes, such as superoxide dismutase (sod) 1 and gshpx. In addition, vitamin D deficiency significantly elevated alcohol-induced upregulation of hepatic proinflammatory cytokines and chemokines. Taken together, these results suggest that vitamin D deficiency aggravates hepatic oxidative stress and inflammation during chronic alcohol-induced liver injury.