Miracle-dz/UniFAR-FTUs huggingface dataset:
Determination of Anti-Mycoplasma Capricolum Subsp. Capripneumoniae Antibodies For The Sero-Epidemiology of Contagious Caprine Pleuropneumonia

Contagious caprine pleuro-pneumonia (CCPP) is fatal disease of goats and causes huge economic losses due to high morbidity and mortality. CCPP is enlisted as notifiable animal disease by OIE. The causative agent of CCPP is Mycoplasma capricolum subsp. capripneumoniae (Mccp). The present study was aimed to investigate the seroprevalence of CCPP in northern Pakistan. The study areas were divided into three zones; northern zone, central zone and tribal zone. A total of 1300 serum samples were collected during November 2017 – April 2019 from goats of different age and sex and were analysed by monoclonal antibody based cELISA. The analyses revealed 227 (17.5%) samples positive for anti-Mccp antibodies. The zone wise distribution of CCPP in goats was significantly different (P˂0.05), indicated by positive sera for Mccp of 23% animals from northern zone followed by 15% and 13% animals from tribal and central zones, respectively. The analysis of data showed non-significant values in the seroprevalence among bucks and doe(s), indicated by anti-Mccp sera from 16.6% bucks and 18.3% doe (s). Moreover, among different age groups the prevalence of disease in adult goats (20%) was significantly (P˂0.05) higher than kids (10.8%). It is evident from the present study that CCPP caused by Mccp is prevalent in Pakistan and both sex of animals are equally susceptible to Mccp infection. Furthermore the disease is more prevalent in northern zone.
Unraveling Gut Microbiota Signatures Associated with PPARD and PARGC1A Genetic Polymorphisms in a Healthy Population

Recent studies have revealed the importance of the gut microbiota in the regulation of metabolic phenotypes of highly prevalent metabolic diseases such as obesity, type II diabetes mellitus (T2DM) and cardiovascular disease. Peroxisome proliferator-activated receptors (PPARs) are a family of ligand-activated nuclear receptors that interact with PPAR-γ co-activator-1α (PPARGC1A) to regulate lipid and glucose metabolism. Genetic polymorphisms in PPARD (rs 2267668; A/G) and PPARGC1A (rs 8192678; G/A) are linked to T2DM. We studied the association between the single-nucleotide polymorphisms (SNPs) rs 2267668 and rs 8192678 and microbiota signatures and their relation to predicted metagenome functions, with the aim of determining possible microbial markers in a healthy population. Body composition, physical exercise and diet were characterized as potential confounders. Microbiota analysis of subjects with PPARGC1A (rs 8192678) and PPARD (rs 2267668) SNPs revealed certain taxa associated with the development of insulin resistance and T2DM. Kyoto encyclopedia of gene and genomes analysis of metabolic pathways predicted from metagenomes highlighted an overrepresentation of ABC sugar transporters for the PPARGC1A (rs 8192678) SNP. Our findings suggest an association between sugar metabolism and the PPARGC1A rs 8192678 (G/A) genotype and support the notion of specific microbiota signatures as factors related to the onset of T2DM.
Complications of Percutaneous Endoscopic Gastrostomy (PEG) Tube Applied to Endoscopy Unit Patients

Background: In patients who find difficulty in eating or who have lost the ability to swallow food, percutaneous endoscopic gastrostomy (PEG) is the preferred method of long-term tube feeding. Although PEG is a usually safe technique, several complications sometimes arise. Objective: To study the advantage and disadvantage of PEG to improve the maneuver and increase the success rate by identification of outcome complications of PEG and their management and evaluation of the efficacy of PEG in improving patient's lifestyles. Patients and methods: This retrospective, single-center study was done on 60 patients who needed PEG tube in the endoscopy unit of internal medicine department, Zagazig University Hospital during the period from December 2020 to May 2021. All patients were subjected to complete relevant evaluation before the study in the form of complete history taking, clinical examination, lab investigation, pelvi-abdominal ultrasound, multislice CT or MRI to assess advanced cancer or peritoneal metastasis and endoscopic examination for outlet patency. Results: A total of 16 patients (26.67 %) had PEG-related complications. Fourteen (23.3 %) patients had minor complications. The most common minor complication recorded was insertion site infection that found in 5 (8.3 %) patients. Two (3.3%) patients in our study reported major PEG-related complications. One (1.7%) patient had massive hematemesis and melena and one (1.7%) patient reported buried bumper syndrome. Conclusion: We concluded that PEG had received global acceptability as a safe approach for administering enteral feeding in patients with inadequate oral intake for more than 28 days and a functioning GI system.
Indigenous Entrepreneurship and Organizational Tensions: When Marginality and Entrepreneurship Meet

This article explores how marginality influences indigenous entrepreneurship through tensions that emerge from the constant threat of seeing indigenous cultures fade away. Based on a qualitative study in Quebec, this article theorizes a process that explains how the context of marginality influences indigenous entrepreneurship. Four concurrent dynamics provide insight into the realities of indigenous entrepreneurship. This article paves the way for new lines of research on indigenous entrepreneurship, the micro-foundations of tensions, and the link between emotions and cognition in managing these tensions.
Rotations in a Seven Story Reinforced Concrete Hotel accompanying Nonlinear Waves During Earthquake Excitation

We model a seven-story, reinforced-concrete building in Van Nuys, California, that was damaged during the 1994 Northridge earthquake. We use a one-dimensional, layered, shear-beam model with bi-linear material properties, and we examine how the rotations (local strains and drifts) in this model depend upon the distribution of the stiffness along the building height, the nonlinear properties of the reinforced concrete, and the nature of strong motion. We show how, following the powerful waves propagating up and down the building, point rotations take place that differ from the corresponding average drift angles. These point rotations are larger near the rigid floor slabs (near the top and bottom ends of the columns, shear walls, and non-structural members found at all floors) and propagate as slow waves up and down the building. These slow rotational waves occur only while the material is experiencing large nonlinear deformations, and their amplitudes grow with ductility. We note that recording these rotational waves in real time may provide a powerful new vehicle for health monitoring of full-scale structures excited by large transient forces when their structural members enter large nonlinear deformations.
Residual Energy Maximization for Wireless Powered Mobile Edge Computing Systems With Mixed-Offloading

This paper studies a joint design of resource allocation and task offloading in a wireless powered mobile edge computing network involving different types of computation tasks. To deal with diverse computation tasks, we explore a mixed-offloading paradigm to support the coexistence of partial and binary offloading modes. Specifically, devices harvest energy from an access point (AP) via wireless power transfer (WPT) and utilize the harvested energy to execute their computation tasks using partial or binary offloading. Based on a practical non-linear energy harvesting model, a residual energy maximization problem is formulated by jointly optimizing the transmit power of the AP, the offloading power of devices, the time allocation on WPT and task offloading, and the task partitions and the binary offloading decisions of devices, which turn out to be a non-convex mixed-integer non-linear programming problem. Thus, we develop an efficient dual-layer optimization algorithm by decomposing the optimization problem into an inner and outer layer structure that aims to obtain resource allocation and offloading decisions. Simulation results show that our proposed scheme achieves residual energy gains compared to existing schemes.
EFFICACY ENHANCEMENT OF FOUR BIO-CONTROL AGENTS AGAINST Spodoptera littoralis (Boisd.) BY FLUORESCENT BRIGHTENER

Efficacy enhancement of four biocontrol agents; Spintor 24% SC (Spinosad), Neemix 4.5% EC (Azadirachtin), Protecto 10% WP (Bacillus thuringiensis) and S. littoralis nucleopolyhedrovirus (SpliNPV) against S. littoralis larvae using Fluorescent Brightener-28 (FB) was investigated. These biocontrol agents were arranged according to LC50 values in the following descending order; Spintor 24% SC (0.097 μg/cm 2 ), Neemix 4.5% EC (0.119 μg/cm 2 ), Protecto 10% WP (0.262μg/ cm 2 ) and SpliNPV (1469.388 PIB’s/mm 2 ). There was no enhancement in the efficacy of Spintor 24% SC or Protecto 10% WP at LC10 and LC25 levels when FB was added at 0.01, 0.1 and 1.0%. On the contrary, Neemix 4.5% EC and SpliNPV were enhanced by combination with of FB concentrations. The highest enhancement effect tested was found with SpliNPV at LC25 value with 1.0% FB, where the co-toxicity factor reached 348.8, 650 and 129.9 5, 6 and 7 days after application, respectively. The results indicated that there was a positive correlation between activity enhancement of Neemix 4.5% EC & SpliNPV and rate of increasing FB concentration. The estimated LT50 value of tested larvae decreased from 7.01 days in the virus alone to 6.91, 6.30 and 5.70 days when FB at 0.01, 0.1 and 1.0% was added to the virus, representing percentage reductions in time which reached 1.4, 10.1 and 18.7%, respectively. Generally, the addition of FB reduced the LC10 and LC25 values of Neemix or SpliNPV and hastened the death of S. littoralis larvae. Also, it was found that the addition of 1% FB to SpliNPV at LC10 caused a decrease in larval weight of S. littoralis reached by 44.1%.
Contrasting Challenges of Urban, Suburban, and Rural First-Generation College Students to Improve Retention Programs

The success of first-generation college students (FGCS) is critical to higher education’s role in promoting equity and social mobility among underrepresented populations. Although research on FGCS exists, a comprehensive literature review demonstrates an overgeneralization of FGCS characteristics in the presentation of the data. This study reviewed literature from 2000 through 2020 to identify barriers to academic success reported by FGCS in urban, suburban, and rural settings. Findings show varying challenges across settings in three themes: issues arising from academic preparation, issues in persistence, and non-academic influences. The implications of this study guide postsecondary institutions in creating more effective retention programs to address the challenges FGCS faces in a given setting. By illuminating differences in FGCS challenges, this study combats overgeneralizations of a diverse and geographically dispersed population of students.
Applications of chitosan and chitosan nanoparticles in fish aquaculture

Fish aquaculture is considered an important agricultural activity capable of ending nutritional deficiencies and contributing to poverty reduction (Kaleem & Sabi, 2021). During the past couple of decades, a remarkable and enormous progression in aquaculture has outpaced capture fisheries. While, in the upcoming years, it is predicted to serve as a principal source of aquatic animal requirements (Maclean, 2003 and Ahmed et al., 2020). Thus, fish demand continues to grow throughout the world moving towards intensive aquaculture systems, especially in the developing countries, where fish are important source of the animal protein and the artificial feeding, where fish form the major component (Maclean, 2003 and Abdel-Ghany & Salem, 2020). Recently, aquaculture has been ARTICLE INFO ABSTRACT Article History: Received: Dec. 25, 2021 Accepted: Jan.3, 2022 Online: Jan. 10, 2022 _______________
Safety culture in the Norwegian Petroleum Industry: Towards an understanding of interorganisational culture devolopment as network learning

In such complex industries as the petroleum industry, the effect and quality of SHE management will to an increasing extent be dependant upon the interaction between many different actors from different cultures and organisations. Processes of cross-cultural learning will thus be of crucial importance for what one can achieve. It is argued in this article that an actor-network theoretical approach could contribute with revealing findings in this area, and bring a deeper understanding of the complexities and relations between culture and learning. Individuals and organisations should be seen as constituted within heterogeneous networks in which knowing and learning not are limited by artificial boundaries, such as ‘departments’, ‘organisations’ or even ‘communities of practice’. The paper discusses and critiques some aspects of safety culture in the petroleum industry as it is described and theorized in the literature. It is further drawing upon central perspectives of actornetwork theory and organizational learning theory to suggest an understanding of safety culture development as ‘network learning’. The article concludes with identifying some areas for future
Analysis on Literature Review of Competency

Currently, human resources management has been viewed as a key strategy to low the cost of human capital and improve an organization’s economic growth. The term of “competency” plays the important role in improving job performance and in turn qualifies human resources. Especially, under the climate of globalization, the workplace requires business practitioners to acquire a new set of knowledge, skills, and attitudes to face the diversity and complication of the new business environment successfully. The main purpose of this study was to analyze a review of the literature concerning the development, models, categorization, paradigm shift. Especially, the study collected Taiwanese research patterns of competency. Moreover, the system of Taiwan TrainQuali System(TTQS) was presented as a successful example in application of competency.
Transmission LossAnalysis of Expansion Chamber Mufflers with Mean Flow

Based on a variational formulation, a generalized three-dimensional acoustic finite element model is first developed to analyze the acoustic characteristics of expansion chamber mufflers with mean flow. The convective effects induced by mean flow are taken into account in the mass, damping and stiffness matrix of the finite element model. In addition, the boundary conditions, including non-reflex terminations and absorptive materials, are derived for transmission loss (TL) analysis. By doing so, the TL with the factors of mean flow, area expansion ratio and absorptive materials is then calculated. Calculation results correlate well with the plane wave theory and those in previous literature for expansion chambers. The effect of mean flow on TL analysis of expansion chambers is obviously found at high frequency. The proposed method is also employed to assess the performance of ladder mufflers. Finally, a novel expansion chamber muffler with inside perforated plates is designed and its effectiveness demonstrated herein.
A Split-GAL4 screen identifies novel sleep-promoting neurons in the Ventral Nerve Cord of Drosophila

As in the mammalian system, sleep in Drosophila is regulated by multiple brain regions. Among them, neurons projecting to the dorsal Fan-Shaped Body (dFB) have been intensively studied and the data suggest they play a critical role in sleep regulation. The 23E10-GAL4 driver is the most widely used tool to label and manipulate dFB neurons. Multiple studies have reported that activation of 23E10-GAL4 neurons promotes sleep. However, anatomical analyses revealed that 23E10-GAL4 labels 23-30 dFB neurons in the Drosophila brain and many non-dFB neurons in the brain and in the Ventral Nerve Cord (VNC), the fly equivalent of the spinal cord. To better understand the role of individual dFB neurons in sleep regulation, we undertook a Split-GAL4 screen to gain access to subsets of 23E10-GAL4 expressing cells. In this study, we report the discovery of two VNC cholinergic sleep-promoting neurons labeled by the 23E10-GAL4 driver.
The molecular basis of flowering time regulation

Flowering is controlled by a series of signals integrated to regulate gene expression and coordinate development. The flowering hormone FLOWERING LOCUS T (FT) positively regulates flowering while the highly homologous TERMINAL FLOWERING 1 (TFL1) negatively regulates flowering. FT is recruited to the promoter in a complex with FD, a transcription factor belonging to the bZIP family, and 14-3-3. This complex is called flowering activating complex (FAC). Here TFL1 is shown to form a complex with 14-3-3 proteins and FD that has striking similarity to the FAC. By probing the extended loop of TFL1 a small region was identified towards the N-terminus of the loop that is involved in mediating the interaction with 14-3-3. This TFL1–14-3-3 platform can interact with the C-terminus of FD, and moreover this interaction occurs between FD and 14-3-3 rather than directly between FD and TFL1 as had been previously speculated. Results indicate that the TFL1–14-3-3 complex, but not FT–14-3-3, can interact with the AP1 promoter from Arabidopsis and that FD is not required for this interaction. In addition, we have located a region of three residues near the C-terminal portion of the loop that when mutated can convert FT from an activator of flowering into a strong repressor of flowering in vivo. Overall, the results suggest that TFL1 can associate with DNA and recruit FD to specific regulatory sites via 14-3-3 proteins, while FT is recruited via FD to a different region within the AP1 promoter region. The data thus provide the basis for a mechanistic model for the antagonistic functions of FT and TFL1 in regulating flowering.
‘It’s like getting your car checked’: the social construction of diabetes risk among participants in a population study

In western industrialised societies, asymptomatic individuals are increasingly labelled as at-risk of future illness and targeted for public health interventions. These at-risk people are identified through health checks, population studies and national screening programs. The main purpose of communicating such risk to individuals is to motivate them to make lifestyle changes. Many of these risk-labels are controversial, both medically and ethically. Based on the relational theory of risk and a thematic analysis of qualitative interviews, we explore how individuals defined as at-risk perceive and conceptualise information about risk of developing diabetes. The interviews were conducted in 2019 with 26 participants from an ongoing population study in Norway. After participating within the screening, participants were informed that they had elevated or intermediate glycated haemoglobin values, and therefore at risk of developing type 2 diabetes. Our data reveal an ambiguous situation: while receiving information about being at-risk may function as a vulnerability-reminder that might motivate lifestyle changes, it can also create unnecessary fear over a disease that may never occur. Danger and uncertainty were interrelated aspects in the ways in which our participants conceptualised risk. Participants risk perceptions seemed to be regulated by fear, followed by a need for reassurance. Differences in risk perceptions and accounts of lifestyle changes depended on people’s trust in expert information versus their own experiences. Trust in medical expertise played a significant role in the ways in which participants constructed their risk, as well as their accounts of lifestyle changes.
The Impact of an Overlaid Ripple Current on Battery Aging: The Development of the SiCWell Dataset

Fast-switching semiconductors induce ripple currents on the high-voltage DC bus in the electric vehicle (EV). This paper describes the methods used in the project SiCWell and a new approach to investigate the influence of these overlaid ripples on the battery in EVs. The ripple current generated by the main inverter is demonstrated with a measurement obtained from an electric vehicle. A simulation model is presented which is based on an artificial reference DC bus, according to ISO 21498-2, and uses driving cycles in order to obtain current profiles relevant for battery cycling. A prototype of a battery cycling tester capable of high frequency and precise ripple current generation was developed and is used to cycle cells with superimposed ripple currents within an aging study. To investigate the impact of the frequency and the amplitude of the currents on the battery’s lifetime, these ripple parameters are varied between different test series. Cell parameters such as impedance and capacity are regularly characterized and the aging of the cells is compared to standard DC cycled reference cells. The aging study includes a total of 60 automotive-sized pouch cells. The evaluation of ripple currents and their impact on the battery can improve the state-of-health diagnosis and remaining-useful life prognosis. For the development and validation of such methods, the cycled cells are monitored with a measurement system that regularly measures current and voltage with a sampling rate of 2 MHz. The resulting dataset is suitable for the design of future ripple current aging studies as well as for the development and validation of aging models and methods for battery diagnosis.
Epidemiology and Outcomes of Hospitalized Adults with SARS-CoV-2 Community-Acquired Pneumonia in Louisville, Kentucky

Background: During the ongoing pandemic of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), SARS-CoV-2 community-acquired pneumonia (CAP) has been the primary cause of hospitalization. The objective of this study was to evaluate the clinical characteristics and outcomes of 1,013 patients hospitalized with SARS-CoV-2 CAP from September 2020 through March 2021 in Louisville, Kentucky. Methods: This was a retrospective observational study of 1,013 patients hospitalized with SARS-CoV-2 CAP at eight of the adult hospitals in the city of Louisville from Septem- ber 2020 through March 2021. Patients with 1) a positive reverse transcriptase-polymerase chain reaction (RT-PCR) for SARS-CoV-2, 2) fever, cough, or shortness of breath, and 3) an infiltrate on chest imaging were defined as having SARS- CoV-2 CAP. Data were abstracted from each hospital’s electronic health record. Descriptive statistics were performed on clinical and epidemiological characteristics of hospitalized patients with SARS-CoV-2 CAP. Demographic characteristics of the study population were compared with census data from the city of Louisville. Data were analyzed by descriptive and inferential statistics using R version 3.4. 0. Results: Of the 1,013 patients hospitalized with SARS-CoV- 2 CAP, the median age was 65 years, 53% were males, 24% reported their race as African American or Black, and 6% identified as Hispanic. The most frequent comorbidities were hypertension (73%), obesity (56%), and diabetes (43%). At the time of admission, 60% required supplemental oxygen. The mortality rate was 19% for the total population and 45% for the 359 patients admitted to the intensive care unit (ICU). For each comorbidity, the proportion of hospital- ized patients with SARS-CoV-2 CAP was significantly different from the Louisville population ( P < 0.001). No significant differences were noted in race or ethnicity compared to the city of Louisville. Conclusions: The elderly, males, and patients with a history of coronary artery disease, cerebrovascular disease, chronic obstructive pulmonary disease, hypertension, diabetes, renal disease, or obesity are overrepresented among hospitalized patients with SARS-CoV-2 CAP compared to the Louisville population. These patients are also more likely to require ICU care and experience worse clinical outcomes, with death oc- curring in approximately one in every five hospitalizations.