Miracle-dz/UniFAR-FTUs huggingface dataset:
Changes in dental care behaviour between 2002 and 2012 and its association with complete dentition in men and women in Switzerland

Background: In industrialized countries, the awareness of oral hygiene measures has increased and the number of missing teeth has been decreasing. A higher number of missing teeth was reported by women despite their more intense oral hygiene. The aim of this study was to compare oral hygiene and its association to oral health with a complete dentition in women and men in Switzerland between 2002 and 2012. Methods: Weighted data from the Swiss-Health-Surveys in 2002 and 2012 were used to quantify the number of missing teeth, the prevalence of prosthetic dental restorations, dental visits and tooth brushing. Sex-stratified logistic regression analysis was performed for subjects aged [≥]65-yrs to assess associations between a complete or functional dentition and dental visits, frequency of tooth brushing and socio-demographic factors. Results: In all age groups, the prevalence of dental visits and frequent tooth brushing increased and the prevalence of missing teeth decreased between 2002 and 2012. In 2012, the prevalence of a complete dentition was 87% in men and 85.3% women aged <25-yrs and 8.2% or 15.6% in the [≥]85-yrs old. Prevalence of dental visits varied between 45.2% in the [≥]85-yrs in 2002 and 73.1% in the 55-65-yrs old in 2012 in women and between 26.0% in the [≥]85-yrs in 2002 and 68.1% in the 55-65-yrs old in 2012 in men. Frequent tooth brushing was more often reported by women (87.7%/81.4%) than men (73.5%/65.5%) in 2012 and 2002. Subjects aged [≥]65-yrs, who visited their dentist within the last year, were twice as likely to have a functional dentition compared to subjects not having visited their dentist in the last year (men: 2.10, 1.68-2.63; women: 2.16, 1.73-2.70) in 2012, in 2002 this association was even stronger. A complete dentition was also associated with high income, higher education and non-smoking in 2012 in men and women. Conclusion: In women and men, oral hygiene practices improved and the mean number of missing teeth substantially decreased between 2002 and 2012. Although women followed oral hygiene recommendations more closely than men, they still do not have a higher prevalence of a complete dentition, except in the oldest age groups.
Oncologic therapy shapes the fitness landscape of clonal hematopoiesis

Clonal hematopoiesis (CH) is frequent in cancer patients and associated with increased risk of therapy related myeloid neoplasms (tMN). To define the relationship between CH, oncologic therapy, and tMN progression, we studied 24,439 cancer patients. We show that previously treated patients have increased rates of CH, with enrichment of mutations in DNA Damage Response (DDR) genes (TP53, PPM1D, CHEK2). Exposure to radiation, platinum and topoisomerase II inhibitors have the strongest association with CH with evidence of dose-dependence and gene-treatment interactions. We validate these associations in serial sampling from 525 patients and show that exposure to cytotoxic and radiation therapy imparts a selective advantage specifically in hematopoietic cells with DDR mutations. In patients who progressed to tMN, the clone at CH demarcated the dominant clone at tMN diagnosis. CH mutational features predict risk of therapy-related myeloid neoplasm in solid tumor patients with clinical implications for early detection and treatment decisions.
MODIC CHANGES AND END PLATE INVOLVEMENT ASSESSMENT BY MRI AND RADIOGRAPHY.

Back ground: Diagnosing low back pain clinically is difficult in certain situations; in such cases identifying the cause can be done by radiological investigations such as plain radiography, MRI. The main factors responsible for low back ache include degenerative disc disease, infective, congenital, neoplastic and non traumatic spondylolisthesis. Aim: The aim of this study is to study the MODIC changes among patients presenting with low back pain and end plate involvement assessment by MRI and radiography. Materials and Methods: Data from all the patients was collected pertaining to age, sex, socioeconomic status, relevant personal history, family history, history of trauma. These patients were advised to undergo Plain radiography and MRI to identify exact cause of low back ache. Results of MODIC changes, anteroposterior, lateral view radiography findings and MRI end plate changes in sagittal T1W, T2W and STIR sequences was entered into spread excel sheet and evaluated. Results: Out of 120 patients with low back ache, 44 (36.6%) patients were noted with MODIC changes by radiography and MRI. Out of 44 patients with MODIC changes, 17 (38.6%) patients who had type II/III and 12 (27.2%) patients who had type II were observed in majority, followed by 7 (15.9%) patients with type I/II, 6 (13.6%) patients with type III and 2 (4.5%) patients with type I. Conclusion: Now-a-days, most number of patients unable to bear pain anymore, so advancement is going more towards accurate diagnosis and early management. In such cases MRI is an ultimate to diagnose the pathology behind Low Back Pain and Plain radiography is readily available in any nearby accessible health care settings.
Development of Application for Identification of Hydrocarbon Prospect Zone In Well Logging Based on Fuzzy Logic

In the oil and gas industry, subsurface well log measurements are typically performed by geoscientists and petro physicists in exploration and production settings. Well logs provide valuable information on the petrophysical properties of underground petroleum reserves. However, random errors and noise during the acquisition process are prone to occur, causing the decision-making phase to be inaccurate. Although most of these problems can be solved today by using advanced acquisition techniques, there is a need for a proper algorithm to be developed to define an accurate hydrocarbon prospect zone. An application that is used for determining the contents zone of hydrocarbon in a drilling well has been developed based on fuzzy logic. This application can predict the hydrocarbon prospect zone as performed by experts. Fuzzy logic is used in the decision-making module by mapping input space into the output with respect to the hydrocarbon prospect zone. This study utilizes log measurements such as gamma ray, resistivity, neutron, and density to estimate the hydrocarbon prospect zone when raw logging procedures. The inference system that is used is Fuzzy Inference System (FIS) - Mamdani. Using test data from refinery wells in East Kalimantan, the proposed application achieves an accuracy level of 90.06%.
Nonlocal TV-Gaussian prior for Bayesian inverse problems with applications to limited CT reconstruction

Bayesian inference methods have been widely applied in inverse problems due to the ability of uncertainty characterization of the estimation. The prior distribution of the unknown plays an essential role in the Bayesian inference, and a good prior distribution can significantly improve the inference results. In this paper, we propose a hybrid prior distribution on combining the nonlocal total variation regularization (NLTV) and the Gaussian distribution, namely NLTG prior. The advantage of this hybrid prior is two-fold. The proposed prior models both texture and geometric structures present in images through the NLTV. The Gaussian reference measure also provides a flexibility of incorporating structure information from a reference image. Some theoretical properties are established for the hybrid prior. We apply the proposed prior to limited tomography reconstruction problem that is difficult due to severe data missing. Both maximum a posteriori and conditional mean estimates are computed through two efficient methods and the numerical experiments validate the advantages and feasibility of the proposed NLTG prior.
Variability and spatial correlation of soil micronutrients and organic matter with macadamia nut production

ABSTRACT Soil fertility is the key to agricultural production. The spatial correlation and location of nutrients may significantly affect the yields. The objective of this work was to evaluate the variability and spatial correlation of iron (Fe), copper (Cu), manganese (Mn), zinc (Zn), and organic matter (OM) with macadamia nut yield. The study was conducted in an Oxisol cultivated for 20 years with macadamia nut in São Mateus, state of Espírito Santo, Brazil. A 100 point grid was used comprising an area of 144 × 140 m with a minimum distance between points of 5 m, in which a single composite soil sample was collected from 0-0.20 m layer for chemical analysis of Fe, Cu, Mn, Zn and OM. Nuts under the canopy’s projection were harvested from February to June, 2015. The data were evaluated by geostatistical analysis using semivariograms, and kriging was used to map spatial distributions of nutrients and nut yield. All evaluated attributes showed strong or moderate spatial dependence structure. The OM was correlated positively with micronutrients, but only Zn was positively correlated with nut yield. Crossed semivariograms adequately explained the maps of Zn and Mn; and Fe showed opposite tendency for macadamia nut yield.
The prognostic factors between different viral etiologies among advanced hepatocellular carcinoma patients receiving sorafenib treatment

Sorafenib is currently the first‐line therapy for advanced hepatocellular carcinoma (aHCC) patients. However, the outcomes and prognostic factors of sorafenib therapy have not been well investigated. We aimed to investigate the pretreatment factors and outcomes among Taiwanese aHCC patients receiving sorafenib treatment. A total of 347 patients with aHCC and well‐compensated liver cirrhosis (Child‐Pugh A) status receiving sorafenib were consecutively enrolled from March 2013 through December 2016. Pre‐treatment clinical data and viral hepatitis markers were collected and analyzed with their outcomes. The primary endpoint of the study was overall survival. The factors associated with overall survival were also investigated. The median overall survival of all the patients was 238 days (range, 9‐1504 days) with a 1‐year overall survival of 43.2%. Positive hepatitis B surface antigen and absence of portal vein thrombosis (PVT) were independent factors associated with better overall survival. The median duration of sorafenib therapy was 93.0 days (range, 4‐1504 days). After stopping sorafenib, the median survival was 93.0 days (range, 1‐1254 days). The 1‐year survival after stopping sorafenib was 21.2%. In chronic hepatitis B patients, total bilirubin level was the only factor associated with overall survival. Hepatitis C antibody RNA negativity, tumor size, PVT, and white blood cell count were the independent factors associated with survival among those chronic hepatitis C patients. There were different prognostic factors stratified by viral etiologies in aHCC patients receiving sorafenib. Viral eradication increased survival in chronic hepatitis C patients.
Diarrhoea incidence prediction using climate data: Machine Learning approaches

Diarrhoea disease pose significant threats to national morbidity and mortality in Vietnam, especially on children below 5 years old. Being a climate sensitive disease, it has strong links to various meteorological factors like rainfall. Together with global climate changes, these meteorological factors have contributed the increasing of Diarrhoea incidence in Vietnam. Thus, having an effective early warning system is becoming an urgent need. However, it has not been paid enough attention with very few research works, mainly focusing on quantilizing the relationships among climate and diarrhoea incidence using linear regressions. Exploring more sophisticated machine learning techniques is therefore an interesting work towards more efficient and effective warning systems. In this paper, different types of prediction models from traditional to deep learning methods are studied for predicting Diarrhoea rate in six provinces in Vietnam in both long- and short-terms. Experiments show that LSTM-ATT acquires better performance compared to all other approaches like SARIMA, CNN, LSTM, Transformer, and Prophet.
Successful abatacept treatment for Felty’s syndrome in a patient with rheumatoid arthritis

Abstract We report the case of a 69-year-old man with a 38-year history of rheumatoid arthritis (RA), who developed Felty’s syndrome, successful treatment with abatacept (ABT). He was treated with etanercept 50 mg/w and methotrexate 8 mg/w for the past 5 years. He was suffered from febrile neutropenia 6 months ago. Etanercept and methotrexate was discontinued 3 months ago, however, neutrophil count was not changed. Abdominal ultrasound showed splenomegaly, the diagnosis of Felty’s syndrome was made. Granulocyte colony-stimulating factor therapy showed no effect on neutropenia, he was treated with ABT. After ABT therapy, absolute neutrophil count was elevated 234/μL to 1840/μL.
Research on the Unethical Conducts and Practices among Professionals in the Construction Industry

Construction industry involved with large number of stakeholders. This industry has a complex contractual structure besides facing with several of psychological human behavior that exposed to the unethical conducts and practices among professionals. Professional ethics warmly has been discussed today within the construction industry. Ethics can be known as a major catalyst for the construction industry to attain status to a successful industry in the worldwide. As a result the aims to be a developed country can be achieved with cooperation from every structural in the construction community. However, without any changes on the unethical conducts and practices among professionals in the construction industry can make it all this becomes useless. Thus, the solid understandings and changes need to be executed, implemented and reinforced to ensure that the problems in the professional ethics can be resolved. This paper discusses and reviews on the unethical conducts and practices among professionals in the different countries such as Malaysia, Pakistan, Australia, Kenya, United Kingdom and China whereby the different behavior will be visible. The most common highlighted for the unethical conducts and practices among professionals in the construction industry were the corruption, negligence, unfair conduct, overriding on audit process over contracting process, favoritism, strict rule, conflict of interest, collusive tendering and violation of environmental ethics. In the previous studies, there were mechanism suggested whereby they are divided into three mechanisms included short, medium and long term solutions based on the project factors which are time, cost and quality. The mechanisms suggested can be catalyst in achieving and enhancing ethical conducts and practices among the professional in the construction industry. This review will provide useful information to every stakeholder in confronting with the unethical conducts and practices among professionals in the construction industry involved
The Role of Food Delivery Services by Online Motorcycle Taxi on the Development of Culinary Home-Based Enterprises

The existence of home-based enterprises (HBEs) as the activities that utilize house as a place both to live and to generate income has been challenged by competition among them. The enterprises can take the advantages of technological advances to overcome this issue. One of the technologies that support the development of HBEs is online motorcycle taxi as a part of innovation in the urban infrastructure. The research case study area is around the area of UNDIP Tembalang-Semarang that is known as an education and housing area with many culinary businesses supplying the needs of students and the local community. Hence, this study takes a case of culinary HBEs that benefits from the existence of food delivery services provided by online motorcycle taxi. This study aims to examine the role of food delivery services provided by online motorcycle taxi in the development of culinary HBEs around the education area. This research uses both quantitative and qualitative descriptive method. The roles of this online services are examined from the perspective of culinary HBEs owners, online motorcycle taxi riders, and the consumers. The result is that there are several roles of online motorcycle taxi services namely maximizing business potential, helping business promotion activities, and providing easy access to customers, can be seen from the increasing income offline and online transactions and also the increasing service coverage of the culinary HBEs.
Genes and speciation: is it time to abandon the biological species concept?

Abstract The biological species concept (BSC) is the cornerstone of neo-Darwinian thinking. In BSC, species do not exchange genes either during or after speciation. However, as gene flow during speciation is increasingly being reported in a substantial literature, it seems time to reassess the revered, but often doubted, BSC. Contrary to the common perception, BSC should expect substantial gene flow at the onset of speciation, not least because geographical isolation develops gradually. Although BSC does not stipulate how speciation begins, it does require a sustained period of isolation for speciation to complete its course. Evidence against BSC must demonstrate that the observed gene flow does not merely occur at the onset of speciation but continues until its completion. Importantly, recent genomic analyses cannot reject this more realistic version of BSC, although future analyses may still prove it wrong. The ultimate acceptance or rejection of BSC is not merely about a historical debate; rather, it is about the fundamental nature of species – are species (and, hence, divergent adaptations) driven by a relatively small number of genes, or by thousands of them? Many levels of biology, ranging from taxonomy to biodiversity, depend on this resolution.
Towards Expanding Quinoa Cultivation in Egypt: The Effect of Compost and Vermicompost on Quinoa Pests, Natural Enemies and Yield under Field Conditions

Increasing production and reducing pests’ population while preserving the environment is an essential goal nowadays. New strategies are needed to achieve this goal, to bridge food gap and achieve food security. Quinoa is a promising crop and could partially substitute wheat in baked products and assist in overcoming wheat gap in Egypt. This study aimed to identify pests and their natural enemies in quinoa plantation, the population dynamics of both and the effect of compost and vermicompost fertilization on pests’ population and quinoa yield under field conditions. The study was carried out in El Giza Research Station of the Agricultural Research Centre—Egypt, from November till March, in two successive seasons, 2016/2017 and 2017/2018. The experiment was set up in a complete randomized block design. Variety Masr 1 was tested and yellow sticky traps were used to monitor insects’ numbers. Three main pests were detected: Aphis craccivora, Empoasca. decipiens and Bemisia tabaci. The most common pest was aphids followed by potato leafhoppers. Compost fertilized quinoa attracted fewer pests and resulted in less yield compared to vermicompost. Parasitoids appeared earlier than predators and their numbers were the highest throughout the two seasons. Pests’ and natural enemies’ peaks were determined to facilitate IPM interventions. It is recommended to use vermicompost in quinoa production rather than compost, as it increased yield, provided that an IPM strategy is implemented in which natural enemies are the main players. Further investigations are needed to understand the interaction between predators and parasitoids in quinoa field in order to maximize the benefit of their existence in IPM programs.
A New Mechanism to Alleviate the Crises of Confidence in Science-With an Application to the Public Goods Game

Creation of empirical knowledge in economics has taken a dramatic turn in the past few decades. One feature of the new research landscape is the nature and extent to which scholars generate data. Today, in nearly every field the experimental approach plays an increasingly crucial role in testing theories and informing organizational decisions. Whereas there is much to appreciate about this revolution, recently a credibility crisis has taken hold across the social sciences, arguing that an important component of Fischer (1935)'s tripod has not been fully embraced: replication. Indeed, while the importance of replications is not debatable scientifically, current incentives are not sufficient to encourage replications from the individual researcher's perspective. We analyze a novel mechanism that promotes replications by leveraging mutually beneficial gains between scholars and editors. We develop a model capturing the trade-offs involved in seeking independent replications before submission of a paper to journals. We demonstrate the operation of this method via an investigation of the effects of Knightian uncertainty on cooperation rates in public goods games, a pervasive and yet largely unexplored feature in the literature.
Bipolar Electrocautery Versus Clipping Endo-Hemostasis during Laparoscopic Castration in Lateral Recumbent Horses -

Principal contest of laparoscopic castration is achieving optimal endo-hemostasis of the testicular blood vessels. The present study was designed to describe and compare two endo-hemostatic techniques; electrocauterization and clipping in lateral recumbent horses. The study was performed on eight horses admitted for routine castration. Multiple technical difficulties associate bipolar electrocauterization technique such as impairment of visibility of the surgical field due to engendered smoke, the necessity for frequent cycles of coagulation-transection, bleeding from improperly coagulated vessels and tissue carbonizing. These difficulties increased the surgical time and decreased the feasibility of the procedure. Meanwhile, Clipping endo-hemostatic technique especially Multi-Fire clipping is advisable as a safe alternative procedure for elective laparoscopic castration in lateral recumbency. It has the superior hemostatic capabilities coupled with simple technical feasibility; two ports, one surgeon and scored the minimal operative time and no intra-operative complications.
Comparison of The Anti-Inflammatory and Immunomodulatory Mechanisms of Two Medicinal Herbs: Meadowsweet (Filipendula ulmaria) and Harpagophytum (Harpagophytum procumbens)

Background: Meadowsweet (Filipendula ulmaria) and Harpagophytum (H. procumbens) are two medicinal herbs traditionally used for their anti-inflammatory effect. Nonetheless, if the effects of the single compounds isolated from these plants have been well described, little is known about the molecular mechanisms behind whole extracts. Methods: We studied and compared the effects of methanolic extracts from the aerial parts of F. ulmaria (FUE) and from the roots of H. procumbens (HPE) on different markers of inflammation such as antioxidant capacity, leukocyte ROS production, COX-2/PGE2 pathway or cytokine secretions. Results: FUE proved to be better than HPE in terms of antioxidant capabilities. Even if their effect on COX-2/PGE2 were similar, we found that their immune-modulatory activities were quite different. In the basal state, the FUE favored cytokines associated with Th1 lymphocytes whereas the HPE decreased the secretion of IL-21 and IL-23, associated with Th17 cells. In PHA-stimulated cells, the HPE increased the characteristic cytokines of Th1 cells, whereas the effects of the FUE were more nuanced. Conclusion: Though both plants are known as anti-inflammatory herbs, these results suggested that, apart from their similar anti-inflammatory effect on COX-2/PGE2, both could improve neutrophil and monocyte recruitment, as well as monocytes/macrophages and Th1, and presumably Th17, activation. Therefore, their impact on immune response was more likely immunostimulant.