Miracle-dz/UniFAR-FTUs huggingface dataset:
Production performance, nutrient use efficiency, and predicted enteric methane emissions in dairy cows under confinement or grazing management system

Abstract There has been an intense debate regarding the economic, social, and environmental sustainability of confinement versus grazing dairy systems. Our goal was to conduct a meta-analysis to compare dry matter intake, milk yield and composition, nutrient use efficiency (i.e., feed efficiency, milk N efficiency), and predicted enteric CH4 emissions using studies that simultaneously evaluated confinement and grazing. We were able to include in the meta-analysis 8 peer-reviewed articles that met the following selection criteria: (1) publication between 1991 and 2021 in English language, (2) report either SEM or SD, (3) inclusion of at least 1 confinement [total mixed ration or fresh cut herbage fed indoors (i.e., zero-grazing)] and 1 grazing treatment in the same study, and (4) use of markers (internal or external) to estimate herbage dry matter intake. Two unpublished experiments were added to the data set resulting in a total of 10 studies for comparing confinement and grazing. The magnitude of the effect (i.e., effect size) was evaluated using weighted raw mean differences between grazing and confinement systems for a random effect model. Enteric CH4 production was predicted as follows: CH4 (g/d) = 33.2 (13.54) + 13.6 (0.33) × dry matter intake + 2.43 (0.245) × neutral detergent fiber. Dry matter intake (–9.5%), milk yield (–9.3%), milk fat yield (–5.8%), milk protein yield (–10%), and energy-corrected milk (–12%) all decreased in grazing versus confined dairy cows. In contrast, concentration of milk fat and feed efficiency (energy-corrected milk/dry matter intake) were not affected by management system. Whereas milk protein concentration increased, milk nitrogen (N) efficiency (milk N/N intake) tended to decrease in grazing compared with confinement. Predicted enteric CH4 production was 6.1% lower in grazing than confined dairy cows. However, CH4 yield (g/kg of dry matter intake) and CH4 intensity (g/kg of energy-corrected milk) did not change between confinement and grazing. In conclusion, while production performance decreased in grazing dairy cows, nutrient use efficiency and predicted enteric CH4 emissions were relatively similar in both management systems. Results of our meta-analysis should be interpreted with caution due to the small number of studies that met our inclusion criteria leading to a limited number of treatment mean comparisons.
Treatment adherence and effect of concurrent statin intensity on the efficacy and safety of alirocumab in a real-life setting: results from ODYSSEY APPRISE

Introduction The phase IIIb open-label ODYSSEY APPRISE study prospectively assessed the safety and efficacy of alirocumab (a proprotein convertase subtilisin/kexin type 9 [PCSK9] inhibitor) in a real-life setting in high cardiovascular risk patients with heterozygous familial hypercholesterolemia or low-density lipoprotein cholesterol (LDL-C) not at goal despite maximally tolerated dose statins ± other lipid-lowering therapies (NCT02476006). This post-hoc analysis assessed patient adherence to statins and alirocumab, plus alirocumab efficacy and safety, according to concomitant statin intensity and prior ezetimibe usage. Material and methods Patients received alirocumab 75 or 150 mg (dose adjustment based on physician’s judgment) every 2 weeks (for ≥ 3 to ≤ 30 months). Results Of 994 enrolled and treated patients, 58.4% received concomitant high-intensity statins, 18.2% received moderate/low-intensity statins, and 23.4% received no statin; 55.9% received prior ezetimibe. Mean alirocumab adherence (percent adherence defined as injections received/theoretical injections × 100) was 96.6% over 72.4 weeks’ mean treatment duration. Mean LDL-C reduction from baseline at Week 12 was similar between statin intensity subgroups (53.6–55.7%). More patients achieved LDL-C < 1.8 mmol/l and/or ≥ 50% reduction from baseline in the ≥ 100% versus < 100% adherent to alirocumab subgroup; high-intensity and low/moderate-intensity subgroups versus no statin subgroup; and prior ezetimibe versus no prior ezetimibe subgroup. Treatment-emergent adverse events occurred in 65.2–75.1% and 68.0–76.3% of patients across statin and ezetimibe subgroups, respectively. Conclusions In a real-life setting, patient adherence to alirocumab was high. Alirocumab provided clinically significant reductions in LDL-C, with most patients achieving LDL-C treatment targets across background statin therapy and prior ezetimibe therapy subgroups.
Epidemio-toxicological profile and reasons for fatal suicidal poisoning: A record-based study in South India

Introduction: Poisoning is the second frequent cause of suicide in India. To plan an effective intervention and awareness program, it is essential to know the sociodemographic profile, pattern, and reasons for suicide. Objective: We conducted this study to find the sociodemographic profile, pattern, and reasons for fatal suicidal poisoning. Methods: We conducted a record-based study in a tertiary hospital in Puducherry. We reviewed autopsies conducted between January 2010 and December 2014 for fatal suicidal poisoning. We extracted data using a data collection sheet for age, gender, marital status, occupation, residence, the reason for suicide, time of injury, time of death. We entered data in Microsoft Excel, and we did a descriptive analysis by using R software version. Results: We reviewed 3996 medicolegal autopsies, out of which 595 cases were of fatal suicidal poisoning. The mean age of the cases was 35.8 years (SD-14.6). The majority of the cases were married (74.8%) for 20–30 years (31.8%). Most of the victims were agriculture workers (22.2%), lived in a rural setting (84.4%), died during the daytime (61.2%), and in the summer season (54.5%). The most common poison used was organophosphates (48.7%), and the most common reason was family problems (30.2%). The median survival time (h) for the cases (n = 564) was 45.8 h (IQR: 16.4 to 110.6). Conclusion: We found fatal suicidal poisoning was common among males, young adults, married, agriculture workers/laborers, and in a rural setting. The findings help plan an effective intervention for suicide prevention in India.
Paleosecular Variations During the Last Glacial Period From Tengchong Qinghai Lake, Yunnan Province, China

In recent years, the evolution of the magnetic flux lobes in terms of location and intensity has been attributed to paleosecular variation of the geomagnetic field, reflecting outer‐core fluid convection close to the core‐mantle boundary. However, most results were based on observational data for the past 400 years supplemented by sparse archeomagnetic studies with data for approximately 3 kyr. In this paper, we construct a relative paleointensity (RPI) record and an inclination record spanning the past ∼90 kyr based on two cores from Tengchong Qinghai Lake (Yunnan Province, China), a closed crater lake that formed in the late Pleistocene. The evolution of flux lobes and the non‐dipole field can be assessed on a much longer time scale. Although the concentration and domain state of magnetic grains in the cores vary significantly, the RPI record is still representative of geomagnetic field features in the region of Yunnan Province, China. The contrasting trends in RPI with the records for eastern China since the late Holocene indicate the southeastward migration of the Siberian flux lobe. During the last glacial period, the RPI records of Tengchong Qinghai Lake and the North Atlantic Ocean show opposite trends, denoting the diverse and strong influence of the two flux lobe systems. The strong reverse flux lobe in the North Atlantic Ocean strengthened the non‐dipole field, while the weak normal flux lobe in Tengchong weakened the non‐dipole field.
Crop Yield Summary for Three Wetland Reservoir Subirrigation Systems in Northwest Ohio

Abstract. Wetland Reservoir Subirrigation Systems (WRSIS) are innovative agricultural water management and recycling systems comprised of three main components; a constructed wetland, a water storage reservoir, and cropland containing subsurface drainage pipe systems. Surface runoff and subsurface drainage from cropland are diverted to a constructed treatment wetland to partially remove nutrients and suspended sediment. Water from the wetland is then routed to a storage reservoir and held there until needed during the growing season for subirrigation. With subirrigation, water from the reservoir is added directly to some of the cropland subsurface drainage pipe systems in order to irrigate the crops through the root zone. Three WRSIS were installed in northwest Ohio; within Defiance, Fulton, and Van Wert Counties. These three sites were operated and monitored from 1996 through 2008. Potential WRSIS benefits included: (1) reduced offsite release of nitrogen nutrients and suspended sediment, (2) additional wetland vegetation and wildlife habitat, and (3) enhanced crop yields. With respect to crop production at all three sites combined, the subirrigated fields within WRSIS, as compared to fields with conventional, unrestricted subsurface drainage, were found to have respectively larger corn (Zea mays) and soybean (Glycine max) yields of 28.7% and 25.2% during dry growing seasons, 14.1% and 6.9% during near average or wet growing seasons, and 19.1% and 12.1% overall. Subirrigated field crop yield results varied between sites with the greatest corn and soybean production increases found at the Fulton County WRSIS, followed by the Van Wert County WRSIS, then the Defiance County WRSIS. At the Defiance County WRSIS, which had high clay content, low hydraulic conductivity soils, a shorter subirrigated field drain line spacing distance (half of what is typical) was found to improve the yield of corn, but not soybeans. This study indicates that WRSIS can provide significant crop yield benefits, especially during dry growing seasons.
Electromagnetic Field Measurements near Macrocellular Base Stations@@@قياس المجال الكهرومغناطيسي قريباً من المحطات القاعدية الخلوية للهاتف الجوال

The levels of electromagnetic radiation (EMR) to which general public is exposed and transmitted from the base stations of cellular mobile radio are investigated. The measurements of power density around base stations located in urban as well as suburban areas are obtained. The measured maximal power density at a level of 2 meters above ground is about 1.4 μW/cm2. The variation of power density with height above ground level is shown to be linear for a relatively limited height range (1-3 meters). The measured average power density is about 1 μW/cm2. The power level is almost steady within the suburban areas while it is rapidly fluctuating in the range of 0.20. 6 μW/cm2 within the urban areas, at distances greater than 40 m from the base stations. The measured level of power density is below the existing RF radiation exposure safety standards.
Indocyanine Green Fluorescence–Guided Lumpectomy of Nonpalpable Breast Cancer Versus Ultrasound-Guided Excision

Purpose The purpose of this study was to evaluate the use of indocyanine green–guided nonpalpable breast cancer lesion localization (INBCL) and to compare it with ultrasound localization (US). Methods We retrospectively reviewed 78 consecutive patients undergoing breast-conserving surgery for nonpalpable breast cancer (NBC). Of all 78 excisions, 42 cases were guided by INBCL and 36 by US. Results The rate of clear margins was 90.5% (38/42) in the INBCL group compared to the 83.3% (30/36) in the US (P = .548). A comparison of the margins at first excision for both INBCL and US, in the INBCL series, 92.9% (39/42) of cases had a margin less than 5 mm, whereas for US series, it was 72.2% (26/36) (P = .033). When results of the excised tissue are taken into account, the mean specimen volume for INBCL was 58 cm3, but for US it was 73 cm3, with difference in mean volume being 15 cm3 (P = .062). Conclusions INBCL for NBCs was more accurate than US because a smaller volume of the tissue may be excised by using the technique, without compromising margin status in nonpalpable lesions.
‘My son has lost his dignity’: dignity of persons with profound intellectual and multiple disabilities

Abstract The objective of this study is to describe and evaluate understandings of dignity of persons with profound intellectual and multiple disabilities. Intrinsic dignity cannot be lost and is inherent to being a human. Also, dignity is the extent to which these persons have enough positive experiences (individual dignity), have dignity in their relationships with familiar others (relational dignity), or with unknown others (societal dignity). While intrinsic dignity sometimes fails to include experiences of these persons and their family members, the other understandings are gradual, which means that these persons can lose their dignity. The understandings express a concern: the life of the person with severe disabilities is, respectively, worth respecting, living, sharing and caring about. We conclude that they can have dignity and that, in case of disagreement, it is important to clarify which dignity is meant and to make explicit the concerns at stake. Points of interest A mother stated, ‘My son has lost his dignity,’ while other parents assert that their child, like any other human being, cannot lose his dignity. The paper clarifies these differences between understandings of dignity. In this study, four understandings of dignity of persons with profound intellectual and multiple disabilities are evaluated. This means that their strengths and limitations are described. Parents and others, referring to dignity of persons with severe disabilities, want to express a concern, this paper argues. They want to make clear that the lives of these persons are worth respecting, living, sharing or caring about. Parents, health care professionals or others who disagree on dignity of a person with severe disabilities, this article concludes, should open themselves up for the other’s concerns. While their concerns may differ, they are both obviously concerned about this person, which is the starting point for providing good care and support.
Association of Non-alcoholic Fatty Liver Disease with Symptomatic and Asymptomatic Cholelithiasis: Cohort from Southeast Asian Patients

Introduction: With increasing prevalence of metabolic syndrome, sedentary lifestyle, and diabetes mellitus the burden of non-alcoholic fatty liver disease (NAFLD) is also increasing along with its complications including gallstone disease. That is why, this study aims to determine the association between non-alcoholic fatty liver disease with the prevalence of gallstone disease and also, risk factors associated with symptomatic and asymptomatic cholelithiasis. Methods: A prospective study design was performed and during the data collection phase we have enrolled a total of 218 patients who were diagnosed as a case of NAFLD from Asian Institute of Medical Sciences, Hyderabad between the periods of 19 months from March 2019 to October 2020. Diagnosis of NAFLD was made using liver biopsy and cholelithiasis with ultrasound abdomen. Both males and females with a primary diagnosis of NAFLD were included in this study. Patients were divided into symptomatic and asymptomatic gallstone disease and were further assessed for underlying risk factor associated with symptomatic and asymptomatic gallstone disease. Statistical package for the social sciences version 21 (SPSS) used for the entry of data and final analysis and a p value of <0.05 were considered as statistically significant. Results: The overall prevalence of gallstone disease in patients with NAFLD was 12.84% (n = 28) among them 19 (67.85%) patients were having symptomatic gallstone disease while 9 patients had asymptomatic gallstones disease (32.14%). Patients having mean age 49.01 years, uncontrolled blood sugar level (209.24 mg/dl), mean alkaline phosphatase 106.22 IU/L, female gender, and having diabetes mellitus were significantly associated with symptomatic gallstones disease (p value <0.05). Conclusion: In our study, the cohorts have shown bidirectional association between gallstone disease and NAFLD. Also prevalence of symptomatic gallstone disease is quite high and it was strongly associated with increasing age, female gender, raised blood glucose levels, and diabetes mellitus.
Job Satisfaction and Turnover Intention: Moderation of Organizational Trust and Organizational Justice

This study aims to analyze the role of organizational trust and organizational justice in moderating the effect of job satisfaction on turnover intention. The population in this study are employees in several information technology companies in Jakarta. The research sample amounts to 195 respondents. Data collection method is done through a questionnaire. Data analysis method uses structural equation modeling-partial least square (SEM-PLS). The results of this study prove that job satisfaction a negative affect on turnover intention. Organizational trust does not affect turnover intention. The interaction of job satisfaction and organizational trust as a moderating variable affects turnover intention. Organizational justice has a negative effect on turnover intention. The interaction of job satisfaction and organizational justice as a moderating variable does not affect turnover intention.
The Impact of Malnutrition on the Quality of Life of Colorectal Cancer Patients in a Tertiary Hospital

Abstract Malnutrition among colorectal cancer patients can impair quality of life and decrease survival. This study evaluated the nutritional status of colorectal cancer patients and its association with quality of life among Filipino colorectal cancer patients seen in a tertiary hospital. A cross-sectional study was conducted among colorectal cancer patients seen at the Philippine General Hospital between December 1, 2019 and February 28, 2020. Nutritional status was evaluated using the Subjective Global Assessment, while quality of life was assessed using the EORTC QLQ-C30. Descriptive statistics, ANOVA and logistic regression were employed for analysis. Among 292 patients, malnutrition was noted in 76.4%. Stage III cancer had a higher odds for malnutrition (OR (odds ratio) = 6.22, 95% confidence interval (CI): 1.59, 24.42). Patients who received or were currently receiving chemotherapy were less likely to develop malnutrition (OR = 0.35, 95% CI: 0.18–0.69). Global health status and all functional subscale scores for the severely malnourished group were lower while the scores for symptom scales increased with the degree of malnutrition. There was a high prevalence of malnutrition among colorectal cancer patients and this was associated with poor quality of life. Future directions emphasizing early nutritional screening and assessment are recommended.
Regional and rural clients’ presenting concerns and experiences of care when engaging with an online substance use counseling service

Abstract Introduction People are increasingly turning to online services for help with substance use concerns. There has, however, been limited research on the use of online substance use services by regional and rural populations. This study explored: (1) the experiences of care of regional and rural clients of an Australian national online text-based substance use counseling service, Counselling Online; (2) their reasons for accessing the service; and (3) their interaction with the counselor. Design and methods We thematically analyzed transcripts of 31 online counseling sessions involving regional and rural clients seeking help for their alcohol, cannabis or amphetamine use. Results Regional and rural clients commonly experienced difficulties accessing local services, were often in distress, and were navigating rurally-influenced social challenges. Counselling Online provided support, education and helped clients explore their substance use. Clients generally found Counselling Online beneficial, however some counselors were unaware of the unique issues affecting regional and rural clients, such as transportation barriers and geographical isolation. Discussion and conclusions Online substance use services provide useful support to regional and rural clients, however we identified several opportunities for improving the service experience for regional and rural clients. These include training online counselors on the unique experiences of regional and rural clients, adapting referrals to match client preferences, and encouraging counselors to ask about the physical location in which clients are using the service.
Determining Significant Risks in the Variability between Design-Stage Elemental Cost Plan and Final Tender Sum

AbstractSeveral researches have indicated that pre-tender estimating inaccuracies are significantly influenced by the level of risk information available to estimators. This study first identifies risk factors that influence variability between design-stage elemental cost plan and final tender sum (contract sum) in traditionally procured commercial building projects. It further evaluates the identified risk factors through risk measurement to determine the most significant ones during design development. Project data from New Zealand were obtained through online questionnaire and interview surveys to determine the construction consultants’ perspectives. Responses to the survey were analyzed by using descriptive statistics, risk mean analysis (RMA), degree of risk, coefficient of variation, and Kendall’s coefficient of concordance. A ranking of mean scores of the survey responses enabled the most significant risk factors to be determined. Interviews were analyzed by using thematic and documentary methods t.
Constructivist Grounded Theory or Interpretive Phenomenology? Methodological Choices Within Specific Study Contexts

Constructivist research methodologies are useful in discerning meanings of experience to subsequently inform and improve healthcare practice. For researchers who philosophically align with the constructivist paradigm, numerous methodologies are available from which to choose to address research questions. However, it can be challenging for researchers, especially novice ones, to choose the most appropriate methodology that aligns with the current state of knowledge of the identified topic, proposed research question, and the study purpose. To reduce the confusion faced by health researchers when choosing an appropriate methodology for a specific study, this paper compares two popular qualitative health research approaches: constructivist grounded theory and interpretive phenomenology. Philosophical underpinnings and the epistemological and ontological evolution of each methodology are explored with similarities and differences highlighted. Manifestation of the philosophical foundations of constructivist grounded theory and interpretive phenomenology are described in relation to data collection, analysis, and the research findings. To illustrate distinctions of each approach and support researchers in the navigation of methodological decision-making, a specific healthcare study context is presented: the rural family members’ experiences of a relative’s interhospital transfer for advanced critical care services. This study context is increasingly being recognized as an important area of healthcare research and practice. However, gaps in knowledge persist, specifically in relation to the experiences of rural family members when a critically ill relative requires an interhospital transfer to a distant urban center for advanced critical care services. Improved understanding of such experiences is necessary to inform the care provided to rural family members, potentially mitigating short and long-term negative consequences for these individuals. Within this example, the importance of the research purpose and research question within a specific study context is underscored as central to appropriate methodological decision-making.