Miracle-dz/UniFAR-FTUs huggingface dataset:
Geosynthetic Reinforced Soil Bridge Abutments

1 Numerical Simulation of Deformation and Failure Behavior of 1 Geosynthetic Reinforced Soil Bridge Abutments 2 3 Yewei Zheng, A.M.ASCE; Patrick J. Fox, F.ASCE; and John S. McCartney, M.ASCE 4 5 Abstract: This paper presents a numerical investigation of the deformation and failure behavior 6 of geosynthetic reinforced soil (GRS) bridge abutments. The backfill soil was characterized 7 using a nonlinear elasto-plastic constitutive model that incorporates a hyperbolic stress-strain 8 relationship with strain softening behavior and the Mohr-Coulomb failure criterion. The geogrid 9 reinforcement was characterized using a hyperbolic load-strain-time model. The abutments were 10 numerically constructed in stages, including soil compaction effects, and then monotonically 11 loaded in stages to failure. Simulation results indicate that a nonlinear reinforcement model is 12 needed to characterize deformation behavior for high applied stress conditions. A parametric 13 study was conducted to investigate the effects of reinforcement, backfill soil, and abutment 14 geometry on abutment deformations and failure. Results indicate that reinforcement spacing, 15 reinforcement stiffness, backfill soil friction angle, and abutment height are the most significant 16 parameters. The shape of the failure surface is controlled by abutment geometry and can be 17 approximated as bilinear. 18 19
An Exploratory Study of the Use of Migrant Remittances at the Household Level in Barbados

Remittances have grown significantly over the last decade worldwide resulting in them becoming a major source of external development finance. In developing countries which account for approximately 74% of all remittances received worldwide, it is recognized that remittances play an essential role in their economic development. With the increasing importance of remittances as a source of capital flows to developing countries there has been a proliferation of research on various aspects of remittances. While studies for the wider Caribbean have focused on multiple aspects of remittances, research on the Barbadian economy has concentrated on the macroeconomic aspect of remittances and their impact on the economy. This paper takes a different approach by examining remittances to Barbados from a microeconomic perspective. In this connection, the paper seeks to determine the demographic profile of persons in Barbados receiving remittances and the primary uses of these remittances. Data were obtained via a survey conducted at the money transfer operator, Money Gram, between April and June 2013. The key finding is that remittances were used mainly for consumption purposes, in particular purchasing food and paying utility bills. This result corroborates the findings of other studies on developing economies.
What counsellors need to know male depression?

The lower prevalence of depression in men has been related to depression not being as well-recognised in men as it is in women. We sought to understand this phenomenon by reviewing the evidence on male depression, concentrating on practices in the UK. Additionally, we aimed to draw conclusions that would contribute to the improvement of health promotion and of the diagnosis for male depression. Our perusal of the available evidence has revealed that some depressed men experience significant difficulties not only in disclosing but also in identifying their depression and that men often exhibit atypical symptoms such as anger. Furthermore, depressed men are often involved in attempts to self-manage their depressive symptoms. This stoic approach compromises the wellbeing of depressed men and it discourages them from accessing appropriate support resources. We conclude with suggestions for practice and research.
Speech Intelligibility in Reverberation is Reduced During Self-Rotation

Speech intelligibility in cocktail party situations has been traditionally studied for stationary sound sources and stationary participants. Here, speech intelligibility and behavior were investigated during active self-rotation of standing participants in a spatialized speech test. We investigated if people would rotate to improve speech intelligibility, and we asked if knowing the target location would be further beneficial. Target sentences randomly appeared at one of four possible locations: 0°, ± 90°, 180° relative to the participant's initial orientation on each trial, while speech-shaped noise was presented from the front (0°). Participants responded naturally with self-rotating motion. Target sentences were presented either without (Audio-only) or with a picture of an avatar (Audio–Visual). In a baseline (Static) condition, people were standing still without visual location cues. Participants’ self-orientation undershot the target location and orientations were close to acoustically optimal. Participants oriented more often in an acoustically optimal way, and speech intelligibility was higher in the Audio–Visual than in the Audio-only condition for the lateral targets. The intelligibility of the individual words in Audio–Visual and Audio-only increased during self-rotation towards the rear target, but it was reduced for the lateral targets when compared to Static, which could be mostly, but not fully, attributed to changes in spatial unmasking. Speech intelligibility prediction based on a model of static spatial unmasking considering self-rotations overestimated the participant performance by 1.4 dB. The results suggest that speech intelligibility is reduced during self-rotation, and that visual cues of location help to achieve more optimal self-rotations and better speech intelligibility.
Cognition and Emotion Distinguishing between level and impact of rumination as predictors of depressive symptoms: An experience sampling study

Rumination — repetitively thinking about one ’ s emotional state, its causes and consequences — exacerbates negative mood and plays an important role in the aetiology and maintenance of depression. Yet, it is unclear whether increased vulnerability to depression is associated with simply how much a person ruminates, or the short-term impact rumination has on a person ’ s negative mood. In the current study, we distinguish between the level versus the impact of rumination, and we examine how each uniquely predicts changes in depressive symptoms over time in an undergraduate sample. Using experience sampling, we assessed students ’ ( N = 101) subjective experiences of positive and negative affect and their use of rumination and distraction in daily life for seven days. Participants also reported their depressive symptoms before and after the experience sampling. Increases in depressive symptoms over the week were predicted by how much people ruminated, but not by its impact on negative mood.
Study the relationship between information management behaviour of grape growers of Vijayapur district of Karnataka

The present study was conducted in Vijayapur district of Karnataka. Vijayapur district was selected purposively as the area under grape cultivation is more in this district in comparison to other district. Two taluks Vijayapur and Indi were selected from the Vijayapur district randomly for drawing the sample of respondents. Twelve villages were selected from each taluk and from each village 10 grape growers were selected on random basis. Total 120 respondents selected for the study. From the both Vijayapur and Indi taluk. The data was collected by personal interview method. Research findings reported that the independent variables like education, annual income, occupation extension contact, mass media size of land holding, organizational participation decision making ability shows highly positive and significant relationship with information management behaviour at 0.05 level of probability. Other variables like age and family size showed non-significant relationship with information management behaviour.
How to build VLSI-efficient neural chips

This paper presents several upper and lower bounds for the number-of-bits required for solving a classification problem, as well as ways in which these bounds can be used to efficiently build neural network chips. The focus will be on complexity aspects pertaining to neural networks: (1) size complexity and depth (size) tradeoffs, and (2) precision of weights and thresholds as well as limited interconnectivity. They show difficult problems-exponential growth in either space (precision and size) and/or time (learning and depth)-when using neural networks for solving general classes of problems (particular cases may enjoy better performances). The bounds for the number-of-bits required for solving a classification problem represent the first step of a general class of constructive algorithms, by showing how the quantization of the input space could be done in O (m{sup 2}n) steps. Here m is the number of examples, while n is the number of dimensions. The second step of the algorithm finds its roots in the implementation of a class of Boolean functions using threshold gates. It is substantiated by mathematical proofs for the size O (mn/{Delta}), and the depth O [log(mn)/log{Delta}] of the resulting network (here {Delta} is the maximum fan in). Using the fan in as a parameter, a full class of solutions can be designed. The third step of the algorithm represents a reduction of the size and an increase of its generalization capabilities. Extensions by using analogue COMPARISONs, allows for real inputs, and increase the generalization capabilities at the expense of longer training times. Finally, several solutions which can lower the size of the resulting neural network are detailed. The interesting aspect is that they are obtained for limited, or even constant, fan-ins. In support of these claims many simulations have been performed and are called upon.
of Women’s Health, Issues & Care Determinants of Low Maternal and Newborn Health Service Utilization in Haiti: A Community-Based Cross-Sectional Study

Background Haiti suffers from among the world’s poorest maternal and newborn health (MNH) indicators and utilization of skilled MNH care remains alarmingly low. In 2013, Enfants du Monde (EdM) and Doctors of the World Switzerland initiated a project aiming to empower women and communities to improve MNH and increase demand for skilled care. During 2013 participatory community assessment (PCA) was conducted, followed by a cross-sectional baseline study in 2014 to better understand the situation and lay the groundwork for implementation of interventions. A cross-sectional design was adopted for the study, using a mixed- methods approach. The quantitative component consisted of a randomized survey of 320 women who had given birth during the previous year living in the intervention area. Qualitative methods included focus groups discussions with women (n=8) and male partners (n=2) and semi-structured interviews (n=10) with health workers: Results in rural compared Notably, (ANC) remains 83% ANC 34% of the attendant. three (63%), (41%) and FGDs and financial barriers remain important obstacles. In addition, women express low satisfaction regarding health services and interactions with providers. These results of the study demonstrate that a number of factors come into play impacting on women’s decision to seek care, reach health facilities and obtain skilled MNH care once at health facilities. Haitian context. These delays have been identified as the following: 1) the delay in deciding to seek appropriate obstetric care; 2) the delay in reaching appropriate services once the decision has been made; and 3) the delay in receiving services once at the health facility [4]. Improving MNH requires taking into consideration and working with women to overcome barriers which present themselves at each delay. While the expansion and improvement of health services is essential to improving MNH and serves to address the third delay in particular, it is equally important to address the first two delays, and more globally to empower women, While geographic and financial barriers remain important, other obstacles are also critical, including the social status of women, preference of care from matrones— traditional birth attendants (TBA) practicing widely in Haiti, and low perceptions of the quality of care and treatment by health care professionals. These studies revealed a number of factors which contribute to preventing women and newborns from accessing MNH services. Effectively improving MNH in Haiti requires action at both the community- and health services-level to address the multitude of factors contributing to low utilization of services.
Assessment of Fluoride Bioaccumulation Potential in African Catfish ( Clarias gariepinus ) Reared in Fluoride Rich Water

Fluoride bioaccumulation in fish poses a significant impact on their growth, survival and consequently to upper trophic levels. Few studies have reported the impacts of high fluoride concentrations and their accumulation potential to catfish in African settings. A 60-day catfish cultivation was conducted at Ngarenanyuki ward and the Nelson Mandela African Institution of Science and Technology (NM-AIST) in Arusha, Tanzania to determine fluoride bioaccumulation and its impacts to catfish growth and survival . Juvenile catfish were exposed to 36 mg F – /L pond water and synthetic water containing fluoride (NaF) concentrations of 5, 15, 36 and 45 mg/L in aquaria set at NM-AIST laboratory. Fluoride concentrations in fish tissues were analysed by ion-selective electrode. Fish survival rate was greater than 90% in ≤ 36 mg/L fluoride levels compared to 65.8% in 45 mg F – /L aquarium. Significant fluoride bioaccumulation was observed in fish bones (222.00 mg/kg, dry weight), gills (177.4 mg/kg), skin (9 mg/kg) and low amount in fillets (1.467 mg/kg). Fluoride bioaccumulation significantly rose with fluoride levels increase and exposure time (p = 0.000). The study concludes that high fluoride occurrence and its increased exposure time increases fluoride bioaccumulation in African catfish. Therefore, growing catfish in water containing ≥ 45 mg F – /L requires defluoridation process.
OPTH_A_356423 385..387

Age-related macular degeneration (AMD) is the leading cause of severe, permanent visual impairment and blindness in people over the age of 60. The World Health Organization (WHO) estimates that 8.7% of global blindness is caused by AMD. The financial burden is enormous with global costs of visual impairment reaching US $343 billion. In 2020, estimated 15.2 million people aged over 50 years were blind worldwide, and an additional 78.8 million had moderate-tosevere vision impairment due to cataracts. Cataract and age-related macular degeneration are common causes of decreased vision, causing visual impairment that often occurs simultaneously. Although modern cataract surgery is a safe and effective treatment for cataract-induced visual loss, some ophthalmologists have had fear in the past that surgery could worsen macular degeneration. This has been disproven by various studies in the past. It was shown that Quality of Life (QOL) benefits were predominant in the group that underwent cataract surgery and that there was no increased risk of progression of maculopathy. Recent clinical and scientific evidence does not find cataract surgery to cause or worsen AMD. Nevertheless, the reduced prognosis and possible effects should be discussed in detail with the patients already preoperatively. The purpose of low-vision rehabilitation is to allow people to resume performing activities of daily living skills (ADLs) and achieving self-autonomy through improved quality of life (QOL), with reading being one of the most important tasks. This is achieved by special training (neuroadaptation) in the use of assistive technology by prescribing appropriate devices, which range from basic magnifiers to high-magnification video-magnifiers to smartphones and tablets to virtual and augmented reality tools. Intraocular vision-improving devices, such as the Implantable Miniature Telescopes (IMT) and intraocular lens (IOL) implants, may be superior to external devices for improving vision in patients with AMD because they provide a more intuitive technology with respect to head motion, vestibular ocular reflex adaptation, and monocular depth perception. However, challenges may remain, for some patients, with adaptation to new bi-ocular vision status. In the past, it has been shown that cost and rehabilitation time are factors in patient management with intraocular devices. Patients require much more intensive care both preand post-implantation, including additional controls and evaluations. Technological improvements and developments have made these implants safer and the procedure itself less dangerous with reduced post-operative sequelae. Therefore, it has become apparent that the limiting factor is not so much of the actual surgery but rather the patient selection and rehabilitation process. It has been shown that these cases are complex and should never be routine interventions. We were also able to show in a multicenter study that testing with conventional visual acuity tests, such as the standard Snellen and Early Treatment Diabetic Retinopathy Study (ETDRS) charts, may be less predictive in determining
Characterization of Isoprenaline- and Salmeterol-Stimulated Interactions between (cid:1) 2 -Adrenoceptors and (cid:1) -Arrestin 2 Using (cid:1) -Galactosidase Complementation in C2C12 Cells

(cid:1) -Arrestin is an adaptor protein that has been shown to couple G protein-coupled receptors (GPCRs) to clathrin-coated pits and target them for subsequent internalization. More recently, (cid:1) -arrestin 2 has also been shown to be involved in the activation of mitogen-activated protein kinase cascades by G pro- tein-coupled receptors independently of G protein activation. Direct interactions between proteins can be monitored using enzyme complementation between two inactive deletion mutants of (cid:1) -galactosidase ( (cid:1) -gal; (cid:1) (cid:2) and (cid:1) (cid:3) ). In the present study, we have used fusion proteins of the human (cid:1) 2 -adreno- ceptor (C-terminal (cid:1) -gal (cid:1) (cid:2) ) and (cid:1) -arrestin 2 ( (cid:1) -gal (cid:1) (cid:3) ) to study directly the pharmacology of this interaction in C2C12 cells expressing the (cid:1) 2 -adrenoceptor- (cid:1) -gal (cid:1) (cid:2) fusion protein at low physiological levels (38.2 (cid:2) 2.7 fmol (cid:1) mg protein (cid:3) 1 ). Isoprenaline, noradrenaline, and adrenaline ( (cid:3) log EC 50 (cid:4) 5.9, 5.5, and 5.7, respectively) stimulated an association between the (cid:1) 2 -adrenoceptor and (cid:1) -arrestin 2 at much higher concentrations the of
Attempt TCP ACK-Storm Based Virtual Network Attacks and Defence Solutions

The rapid development of the digital age has been pushing people to access a mobile working environment when handsets are becoming more diverse and convenient with the help of Virtualization Technology. The speed and usability of Virtualization Technology are astounding for saving initial investment costs and optimizing IT infrastructure. Such Virtualization Technology is what businesses are interested in and makes the virtual server market growing strongly, especially for businesses that have many branches. However, virtual systems (hypervisors) are more vulnerable than traditional servers according due to many network attacks from curious users. Therefore, it's necessary to prepare for the worst circumstances, understand clearly, and research for new threats that can break down the virtual system. In this paper, we attempt to demonstrate the TCP ACK storm based DoS (Denial of Service) attack on virtual and Docker networks to show the threats that easily are happen on services deploying on virtual networks. Based on such consequence, we propose some solutions to prevent our virtual system from potential risks.
the (IOP-29) with the Test of Memory Malingering (TOMM) in symptom validity A study with a Portuguese sample of experimental feigners

This study tested whether combining the Inventory of Problems – 29 (IOP-29) with the Test of Memory Malingering (TOMM) would increase sensitivity in the detection of experimentally feigned mental health problems, compared to using either test alone. Additionally, it also evaluated (a) the effects of administration order of these two tests and (b) the cultural and linguistic applicability of these tests to a European Portuguese population. The IOP-29 and TOMM were administered to a community sample of 100 nonclinical, adult volunteers from Portugal, with the instruction to feign mental health problems. Half were instructed to feign mild traumatic brain injury (mTBI) symptoms, half were instructed to feign major depression. Administration order had no effects on the tests’ scores, and both measures produced excellent sensitivity values, ranging from . 82 to . 98 for the TOMM, and from . 88 to 1.00 for the IOP-29, when using standard a-priori cut-off scores. More importantly, combining the results of TOMM with those of IOP-29 notably increased sensitivity compared to using either test alone. This study thus supports the use of the IOP-29 together with the TOMM in multi-method symptom validity assessments and provides initial evidence that both tests can be used also in Portugal.
drives triple-negative breast cancer metastasis through reduction of lipid-droplet abundance and stimulation of fatty acid oxidation.

Triple-negative breast cancer (TNBC) is notoriously aggressive with high metastatic potential, which has recently been linked to high rates of fatty acid oxidation (FAO). Here we report the mechanism of lipid metabolism dysregulation in TNBC through the prometastatic protein, CUB-domain containing protein 1 (CDCP1). We show that a “ low-lipid ” phenotype is characteristic of breast cancer cells compared with normal breast epithelial cells and negatively correlates with invasiveness in 3D culture. Using coherent anti-Stokes Raman scattering and two-photon excited fluorescence microscopy, we show that CDCP1 depletes lipids from cytoplasmic lipid droplets (LDs) through reduced acyl-CoA production and increased lipid utili- zation in the mitochondria through FAO, fueling oxidative phosphorylation. These findings are supported by CDCP1 ’ s interaction with and inhibition of acyl CoA-synthetase ligase (ACSL) activity. Impor- tantly, CDCP1 knockdown increases LD abundance and reduces TNBC 2D migration in vitro, which can be partially rescued by the ACSL inhibitor, Triacsin C. Furthermore, CDCP1 knockdown reduced 3D invasion, which can be rescued by ACSL3 co-knockdown. In vivo, inhibiting CDCP1 activity with an engineered blocking fragment (extracellular portion of cleaved CDCP1) lead to increased LD abun- dance in primary tumors, decreased metastasis, ACSL activity in two animal models of TNBC. metastases in prognostic marker metastatic for the development of TNBC therapeutics to specifically block CDCP1-driven FAO and oxidative phosphorylation, which contribute to TNBC migration and metastasis. therapeutic targets for blocking TNBC metastasis: cell-surface antigen CUB- domain containing protein 1 (CDCP1) and proteins in the lipid metabolism pathway. CDCP1 regulates lipid metabolism by re- ducing cytoplasmic lipid droplet abundance, stimulating fatty acid oxidation and oxidative phosphorylation. This metabolic pathway likely contributes to the energy production required for cell migration and metastasis of TNBC, and represents a potential therapeutic target.