Miracle-dz/UniFAR-FTUs huggingface dataset:
Effects of Soymilk on Serum Insulinemic Status and High Sensitivity C-Reactive Protein Levels in Healthy Postmenopausal Women of Bangladesh

Background: Postmenopausal women are at increased risk for cardiac diseases because many risk factors are aggravated by menopause. Isoflavones are phytoestrogens present in natural sources, and they may modulate risk factors favorably, involving mechanisms similar to estrogen. The study aimed to assess the effects of soymilk on serum insulinemic status and hs-C reactive protein (CRP) levels of postmenopausal women of Bangladesh. Methods: Thirty-six women (aged 50 ± 5 years, M ± SD) participated in a randomized, un-blind, open-ended, crossover study design for 52 days. During the study period, the patients made four visits (before and after the intervention including the washout period). The soymilk group consumed 350 mL of milk twice a day for 21 days; the milk contained ~30 mg of isoflavones. Fasting blood glucose (FBG), postprandial glucose (PPG), HbA1c, serum insulin, and hs-CRP were measured on day 0, day 21, day 31, and day 51 with a 10-day washout period. Paired t-test was performed to determine the effects of soymilk on the CVD risks among postmenopausal women and a student t-test was p The mean (±SD) of soymilk in glycemic, After crossover, No nificantly at the end of 51 days. Conclusions: Soy isoflavones did not improve serum insulinemic status and hs-C reactive protein (CRP) levels among Bangladeshi postmenopausal women. Further studies need to be elucidated by considering a follow-up study with a large sample size.
MiR-223-3p affects myocardial inflammation and apoptosis following myocardial infarction via targeting FBXW7

Background Myocardial infarction (MI) is one of the main causes of disability and death in the world, leading to myocarditis and cardiomyocyte apoptosis. Studies have shown that microRNA (miRNA) is involved in myocarditis and apoptosis. The main purpose of this study was to explore the regulatory mechanism of miR-223-3p on myocarditis and apoptosis after MI. Methods We cultured H9c2 cells and detected the expression of miR-223-3p in cells treated with different concentrations of H2O2. Sprague Dawley (SD) rats were fed with normal diet, constructed an MI model and detect the expression of miR-223-3p in heart tissue. Overexpression or inhibition of miR-223-3p was conducted in MI model cells in vitro, and the contents of the inflammatory factors tumor necrosis factor-α (TNF-α), interleukin-6 (IL-6), and interleukin-10 (IL-10) in cell supernatant were detected by enzyme-linked immunosorbent assay (ELISA). Cell apoptosis was detected by flow cytometry. Luciferase activity assay was used to detect the targeting relationship between miR-223-3p and FBXW7, and the expression of FBXW7 in cells was also detected. Overexpression of miR-223-3p was performed in MI rats to detect the expression of inflammatory factors, FBXW7, and apoptosis in rat cardiac tissue. Results The expression of miR-223-3p was down regulated in MI models established in vitro and in vivo. Overexpression of miR-223-3p can inhibit inflammatory response and apoptosis in H9c2 cells and cardiac tissues. It was revealed that miR-223-3p can inhibit the expression of FBXW7, reduce myocarditis and apoptosis after MI, and improve cardiac function. Conclusions It is possible that miR-223-3p reduces myocarditis and apoptosis after MI and improves cardiac function by targeted inhibition of FBXW7 expression.
How the simultaneous usage of multiple screens affects information processing and advertising effectiveness

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The Language of War: A Conceptual Replication and Extension of Abe (2012) and Matsumoto and Hwang (2013)

Legislative bodies have very important roles and understanding the psychology of their decision-making processes is a useful area of study. We add to this area by replicating two previous studies: Abe (2012) and Matsumoto and Hwang (2013) in the context of a legislative body. The present study hypothesized that legislators who support war measures would be externally focused and less cognitively complex in their speeches, while opponents of war measures would be internally focused. Speeches were obtained pertaining to the decisions for the U.S. to take military action in Kosovo, Iraq, and Libya. While we found mixed results depending on the circumstances of a speciﬁc conﬂict, we demonstrate how automated language analysis can be combined with voting records to better understand behavioral action, such as legislative decision.
Sequential Application of Column Leaching and Plant Uptake Tests to Assess the Effect of Various Commercial Amendments on Cu Immobilization in Ultra-High Cu-Contaminated Soil

The presence of copper (Cu)-contaminated soil has increased recently due to agricultural and industrial activities. Immobilization techniques using soil amendments have attracted significant research because of their cost-effectiveness, eco-friendliness, and community acceptance. This study used various commercial amendments, including magnetite (M), talc (T), activated carbon (AC), and cornstarch (CS), to immobilize Cu in soil contaminated by acidic waste materials with Cu in Korea (9546 ± 5 mg/kg). To evaluate the immobilizing effect of these amendments, this study applied a sequential process of column leaching and plant uptake tests to observe the ability of Cu to remain in soil with and without amendments through the Cu removal rate. The amendments were characterized by SEM, XRD, and specific surface area and applied to the soil at a rate of 2% (w/w). The first stage of evaluation, i.e., the column leaching test, was conducted by continuously pumping distilled water (DW) for 28 days, and the second stage of evaluation, i.e., the plant uptake test, was started immediately after by planting 10-day-old lettuce seedlings for 28 days. The experimental results showed that all of the amendments had a significant effect on Cu immobilization Cu in soil (p < 0.05), and the T treatment showed the highest efficiency in Cu immobilization, with only 47.0% Cu loss compared to 73.5% in the control soil when assessed by sequential column leaching and plant uptake tests. In conclusion, this study provides an effective assessment method to evaluate the effect of amendments on Cu immobilization in soil, as well as providing feasible options to immobilize Cu using commercial amendments.
Graded betti numbers and shifts of the symbolic power of a general star configuration in ℙ n

Abstract In [37] the author finds a graded minimal free resolution of the 2-nd order symbolic power of a general star configuration in of any codimension r, which generalizes the result of Galetto et al. in [18, Theorem 5.3], and of Geramita et al. in [20, Theorem 3.2]. In [33] we find a graded minimal free resolution of the m-th order symbolic power of a general star configuration in of codimension r for m = 3, 4 with and also find them for codimension 2 with any In this paper, we show how to find a closed formula of graded Betti numbers and shifts of the symbolic power of a general star configuration in of any codimension r based on representation theory and matroid configurations for which generalizes the result of Biermann et al. in [3, Corollary 5.7] and [31, Proposition 7.9]. We also show an example of our methods to find a closed formula of their graded Betti numbers and shifts for any codimension r with
Stochastic estimation of the distribution of soil water repellency on the soil surface in a humid‐temperate forest

Soil water repellency (SWR) increases surface runoff and preferential flows. Thus, quantitative evaluation of SWR distribution is necessary to understand water movements. Because the variability of SWR distribution makes it difficult to measure directly, we developed a method for estimating an SWR distribution index, defined as the areal fraction of surface soil showing SWR (SWRarea). The theoretical basis of the method is as follows: (1) SWRarea is equivalent to the probability that a position on the soil surface is drier than the critical water content (CWC); SWR is present (droplets absorbed in >10 s) when the soil surface is drier than the CWC and absent when it is wetter. (2) CWC and soil moisture content (θ) are normally distributed independent variables. (3) Thus, based on probability theory, the cumulative normal distribution of θ – CWC (f(x)) can be obtained from the distributions of CWC and θ, and f(0), the cumulative probability that θ – CWC < 0, gives the SWRarea. To investigate whether the method gives reasonable results, we repeatedly measured θ at 0–5 cm depth and determined the water repellency of the soil surface at multiple points in fixed plots with different soils and topography in a humid‐temperate forest. We then calculated the CWC from the observed θ–SWR relationship at each point. We tested the normality of the CWC and θ distributions and the correlation between CWC and θ. Then, we determined f(x) from the CWC and θ distributions and estimated the SWRarea on each measurement day. Although CWC and θ were both normally distributed, in many cases they were correlated. Nevertheless, the CWC–θ dependency had little effect on the estimation error, and f(x) explained 69% of the SWRarea variability. Our findings show that a stochastic approach is useful for estimating SWRarea.
Determination of the Size of a Proposed Bike-Sharing Program in Las Vegas, Nevada

Bike-share systems have been installed in cities worldwide as a way to attract travelers to use transit rather than the automobile. This has been proved to be an effective way of mitigating congestion on the road. The objective of this study is to develop a method to determine the size of the bike-share program in terms of the number of bicycles, the number and location of the stations, the number of docks at each station. To achieve the objectives of this study, a literature review was conducted on university bike-sharing systems in the U.S. and abroad. Various cases of bike-share programs were analyzed, in which each case consisted of a different number and location of bike-share stations. The demand corresponding to these stations was used as the input to a simulation model developed in this study to determine the number of docks in stations and bicycles in the system on and around campus at UNLV. These sizing parameters of the bike-share system then were used in a cost and benefit analysis to determine which cases could achieve maximum benefit, given a limitation of the initial costs. It was found that provision of one peripheral station and three internal stations at strategic locations provide relatively higher benefit cost ratio at lower initial cost.
Ability of dairy cows to ensure reproduction in contrasted grass-based systems: The cow for the system?

Reproductive performance of dairy cows has been declining while their milk production was improving. The strong genetic selection that was applied on milk production is considered to be responsible for this. Each step of the reproductive process has been impacted: abnormal ovarian activity is more common in the current population, the duration and intensity of oestrus has dramatically decreased and the occurrence of pregnancy failures has increased. The consensus in the literature is that reproduction is impaired because dairy cows are investing most of their resources in milk production. The aim of this Ph.D. thesis is to explore the effect of alternative selection strategies based on milk fat and protein content on robustness of dairy cows. Our hypotheses were that at similar genetic merit for milk solids yield, compared to cows with high genetic merit for milk yield, dairy cows with high genetic merit for fat and protein contents (i) are exporting less energy in milk and are consequently safeguarding their body reserve; (ii) have better reproductive performance (earlier resumption of ovarian activity, more intense oestrus, better ability to ensure pregnancy). Our results suggest that cows selected for production through high fat and protein content instead of high milk yield would resume ovarian activity earlier, have similar oestrus intensity but more pregnancy failures. These intriguing results suggest that the steps of the reproductive process are genetically partly disentangled. Selecting dairy cows for fat and protein content is not a promising way to improve reproduction while maintaining production performance.
A model of multiple tumor marker for lymph node metastasis assessment in colorectal cancer: a retrospective study

Background Assessment of colorectal cancer (CRC) lymph node metastasis (LNM) is critical to the decision of surgery, prognosis, and therapy strategy. In this study, we aimed to develop and validate a multiple tumor marker nomogram for predicting LNM in CRC patients. Methods A total of 674 patients who met the inclusion criteria were collected and randomly divided into primary cohort and internal test cohort at a ratio of 7:3. An external test cohort enrolled 178 CRC patients from the West China Hospital. Clinicopathologic variables were obtained from electronic medical records. The least absolute shrinkage and selection operator (LASSO) and interquartile range analysis were carried out for variable dimensionality reduction and feature selection. Multivariate logistic regression analysis was conducted to develop predictive models of LNM. The performance of the established models was evaluated by the receiver operating characteristic (ROC) curve, calibration belt, and clinical usefulness. Results Based on minimum criteria, 18 potential features were reduced to six predictors by LASSO and interquartile range in the primary cohort. The model demonstrated good discrimination and ROC curve (AUC = 0.721 in the internal test cohort, AUC = 0.758 in the external test cohort) in LNM assessment. Good calibration was shown for the probability of CRC LNM in the internal and external test cohorts. Decision curve analysis illustrated that multi-tumor markers nomogram was clinically useful. Conclusions The study proposed a reliable nomogram that could be efficiently and conveniently utilized to facilitate the assessment of individually-tailored LNM in patients with CRC, complementing imaging and biopsy tests.
Can Economic Growth Reduce Public Dissatisfaction? Evidence from a Panel Threshold Model in Chinese Cities

Much is known about the relationship between economic growth and satisfaction, while little is known about the relationship between economic growth and dissatisfaction. This study measures the levels of public dissatisfaction in 36 Chinese cities from 2011 to 2018 using data from an official online petition platform. We construct panel data to analyze the impact of per capita GDP and per capita income on public dissatisfaction. The results show that per capita income has a significant negative effect on public dissatisfaction, but only once the per capita income exceeds a threshold amount. In the extended discussion, the nonlinear relationship between income and public dissatisfaction is described as a stair-shaped curve. The results imply the need for developing countries to adhere to economic policies based on income maximization.
COVID‐19 in rural Africa: Food access disruptions, food insecurity and coping strategies in Kenya, Namibia, and Tanzania

Abstract This study assesses the extent of COVID‐19‐related food insecurity in Kenya, Tanzania, and Namibia. Using the Household Food Insecurity Access Scale, we measure food insecurity in various dimensions and document several food access disruptions associated with the COVID‐19 pandemic between April and July 2020. Furthermore, we assess the association of COVID‐19 countermeasures with the adoption of various strategies in line with the coping strategies index. We rely on a unique phone survey that followed households who participated in an earlier field‐based survey. First, through Ordinary Least‐Squares and Probit regressions, we show a strong and statistically significant association between COVID‐19 countermeasures and food access disruptions and food insecurity in each of the three countries. We then use a multivariate probit regression model to understand the use of the various coping strategies, including reducing food intake, increasing food search, and relying more on less nutritious foods. We provide evidence on the complementarities and trade‐offs in using these coping strategies. COVID‐19 and related lockdown measures coincided with a deleterious increase in food insecurity in rural Africa.
Clinical Potential of Dental Pulp Stem Cells in Pulp Regeneration: Current Endodontic Progress and Future Perspectives

Dental caries is a common disease that not only destroys the rigid structure of the teeth but also causes pulp necrosis in severe cases. Once pulp necrosis has occurred, the most common treatment is to remove the damaged pulp tissue, leading to a loss of tooth vitality and increased tooth fragility. Dental pulp stem cells (DPSCs) isolated from pulp tissue exhibit mesenchymal stem cell-like characteristics and are considered ideal candidates for regenerating damaged dental pulp tissue owing to their multipotency, high proliferation rate, and viability after cryopreservation. Importantly, DPSCs do not elicit an allogeneic immune response because they are non-immunogenic and exhibit potent immunosuppressive properties. Here, we provide an up-to-date review of the clinical applicability and potential of DPSCs, as well as emerging trends in the regeneration of damaged pulp tissue. In addition, we suggest the possibility of using DPSCs as a resource for allogeneic transplantation and provide a perspective for their clinical application in pulp regeneration.
“If I Didn’t Have Them, I’m Not Sure How I Would Have Coped with Everything Myself”: Empowering and Supporting Parents/Carers of High-Risk Young People Assisted by Community Forensic CAMHS

Abstract Parent/carer involvement in their child’s support for mental health difficulties is a critical component of effective care. 13 Community Forensic Child and Adolescent Mental Health Services (F:CAMHS) across England were developed to provide specialist support to young people at high risk of harm to self and in particular others, and their families. The aim of this study is to explore parent/carer experiences of Community F:CAMHS. Thematic analysis of interviews (N = 18, from 5 sites) was conducted. Superordinate themes generated focused on 1) facilitators; and 2) barriers to support. Subthemes generated relate primarily to facilitators, particularly empowering parents/carers through the co-production of strategies to help, “holding” cases (taking ownership), and acting on behalf of and supporting parents/carers. Managing clear, joined-up communication across multi-agencies is also of key importance. Barriers to effective support are a lack of joined-up communication at the beginning of the implementation of the services, awareness of Community F:CAMHS, and limited contact. Implications, including the need to further embed the Community F:CAMHS offering in the overall provision of support for this population are discussed. Areas for future research are identified, including the exploration of how young people's characteristics and outcomes may impact parents/carers’ experiences of interacting with services.
A Multi-Eavesdropper Scheme Against RIS Secured LoS-Dominated Channel

Reconfigurable intelligent surface (RIS) has been shown as a promising technique to increase the channel randomness for secret key generation (SKG) in low-entropy channels (e.g., static or line-of-sight (LoS)), without small-scale fading. In this letter, we show that even with the aid of RIS, collaborative eavesdroppers (Eves) can still estimate the legitimate Alice-Bob channel and erode their secret key rates (SKRs), since the RIS induced randomness is also reflected in the Eves’ observations. Conditioned on Eves’ observations, if the entropy of RIS-combined legitimate channel is zero, Eves are able to estimate it and its secret key. Leveraging this, we design a multi-Eve scheme against the RIS-secured LoS dominated scenarios, by using the multiple Eves’ observations to reconstruct the RIS-combined legitimate channel. We further deduce a closed-form secret key leakage rate under our designed multi-Eve scheme, and demonstrate the results via simulations.
comparative study between McCoy laryngoscope versus the tascope in orotracheal intubation in adult surgical patients undergoing general anaesthesia

Introduction: McCoy laryngoscope and video laryngoscopes are being increasingly used as they offer advantages over the conventional laryngoscopes in airway management. The aim of this study is to compare and evaluate the efficacy of McCoy laryngoscope and TAScope in providing good glottic view and ease of intubation and observing the hemodynamic stress response. Materials and Methods: It is a randomised study including 60 patients aged 18-60 years with ASA grade I and II, divided equally in Group M and Group T, posted for elective surgery. Ease of intubation was evaluated by intubation difficulty score(IDS). Hemodynamic parameters, intubation time and airway trauma were compared in both the groups. Results: IDS TOTAL was higher in group M and was statistically significant (p<0.001). The mean time taken for intubation in group T was 46.08seconds and 26.53seconds in group M (p<0.001). There was a transient increase in pulse and blood pressure after laryngoscopy in both the groups but rise were less in group T. Less airway trauma was observed in group M as compared to group T. TAScope took more time compared to McCoy but it resulted in better first attempt intubation, provided more haemodynamic stability and less airway trauma as compared to McCoy.