Miracle-dz/UniFAR-FTUs huggingface dataset:
The influence of Career Development and Management Support on Employee Performance PT Bank Rakyat Indonesia (Persero) Wonosari Branch Office mediated by Employee Engagement

This study aims to analyze the effect of career development and management support on employee performance of PT Bank Rakyat Indonesia (Persero) Wonosari Branch Office mediated by employee engagement. This study uses Partial Least Square to determine the relationship so that researchers use the Smart PLS application to determine the relationship between employee performance variables. The sample in this study were employees within the scope of PT Bank Rakyat Indonesia (Persero) Wonosari Branch Office totaling 90 employees. This study uses quantitative data by distributing questionnaires to all samples studied. Based on outer testing, this study passed the validity and reliability tests. While based on the Inner model, the results show that management support positively has a significant positive effect on employee engagement. However, career development on employee performance, management support on employee performance, career development on employee engagement, management support on employee engagement, has no significant effect. For PT Bank Rakyat Indonesia (Persero) Wonosari Branch Office, it is recommended to further improve company facilities in this case management support and career development in order to improve employee performance in the future. For further research, it is expected to increase the number of respondents, because the amount of research data greatly affects the results of the analysis.
Regular Exercise Throughout Pregnancy and Maternal Recovery Postpartum

2 Introduction.3 Methods.5 Search Strategy and Selection Criteria.5 Results.8 Literature Search Results.8 Literature Review Results.11 Decrease in the need for Caesarean Delivery.11 Decrease in Requests for Analgesia During Labor.12 Decrease in Excessive Weight Gain in Pregnancy.13 Additional Findings.13 Discussion.15 Limitations.16 Conclusion.17 Implications for Practice.18 Implications for Research.19 References.20
Direct evidence of lipid transport by the Drs2–Cdc50 flippase upon truncation of its terminal regions

Abstract P4‐ATPases in complex with Cdc50 subunits are lipid flippases that couple ATP hydrolysis with lipid transport to the cytoplasmic leaflet of membranes to create lipid asymmetry. Such vectorial transport has been shown to contribute to vesicle formation in the late secretory pathway. Some flippases are regulated by autoinhibitory regions that can be destabilized by protein kinase‐mediated phosphorylation and possibly by binding of cytosolic proteins. In addition, the binding of lipids to flippases may also induce conformational changes required for the activity of these transporters. Here, we address the role of phosphatidylinositol‐4‐phosphate (PI4P) and the terminal autoinhibitory tails on the lipid flipping activity of the yeast lipid flippase Drs2–Cdc50. By functionally reconstituting the full‐length and truncated forms of Drs2 in a 1:1 complex with the Cdc50 subunit, we provide compelling evidence that lipid flippase activity is exclusively detected for the truncated Drs2 variant and is dependent on the presence of the phosphoinositide PI4P. These findings highlight the critical role of phosphoinositides as lipid co‐factors in the regulation of lipid transport by the Drs2–Cdc50 flippase.
Transcriptional alteration of NF-κB-associated long noncoding RNAs in the stomach of Helicobacter pylori-infected and non-infected patients.

INTRODUCTION Helicobacter pylori could colonize the gastric mucosa and cause gastritis, ulcers and cancer. Numerous virulence factors have been identified in this bacterium that play important roles in promoting gastric disorders. Although the interaction of long noncoding RNAs (lncRNAs) with transcription, processing, and translation of genes associated with different diseases are described, their interaction with the inflammatory genes and H. pylori infection in the gastric tissue is not well known. This study compared changes in common NF-κB-regulatory lncRNAs in the gastric tissue of H. pylori-infected and non-infected patients with gastritis. Moreover, a link between the virulence entity of the strains and the transcriptional changes was analyzed. METHODOLOGY Two groups of infected and non-infected patients with chronic gastritis were included in the study. Genotyping of the H. pylori strains was done by PCR and relative changes in the expression of NF-κB and regulatory lncRNAs, lincRNA-p21, MALAT1, NKILA, were measured by relative quantitative real time-PCR. RESULTS Transcriptional levels of MALAT1, lincRNA-p21, and NKILA genes decreased in the infected patients compared with the non-infected patients, which was significantly linked with increased NF-κB gene expression. Our results showed that a hypervirulent strain of H. pylori with oipA"on"/HP-NAP+/iceA1+/iceA2+/vacA s1m1/s1m2+/cagA+ genotype can promote a higher level of NF-κB transcription in the inflamed tissue. CONCLUSIONS H. pylori infection could promote down-regulation of lincRNA-p21, MALAT1 and NKILA in the infected gastric tissue in correlation with NF-κB upregulation. More detailed studies are needed to show a link between the virulence genes and their impact on the regulation of lncRNAs in the stomach.
Original Research Article Effect of Radiotherapy on Flexural Strength of Luting Cementsan In Vitro Study

Aim - The aim of this study was to evaluate changes in the flexural strength of luting cements due to radiotherapy. Methodology- Total of 90 rectangular specimens of 25×2×2 mm dimension were fabricated by utilizing the putty consistency polyvinyl siloxane rubber mould. They were grouped based on their type. Group A included 30 specimens made of zinc phosphate cement, Group B included 30 specimens fabricated using glass ionomer luting cement, and Group C consisted of 30 specimen’s fabricated using resin luting cement. Once the specimens were set, they were stored in distilled water between the experiments. After 24 hours, 15 from each group of the mentioned cements were subjected to irradiation fractionally upto 60 Gy by a Cobalt-60 external beam machine. Remaining specimens from each group were used as controls. After radiotherapy, the specimens were stored in distil water for 24 hours until performing the 3 point bend test. All the specimens were subjected to 3 point bend test on universal testing machine for checking flexural strength. Statistics- Kruskal Wallis Test followed by Mann Whitney test as post hoc analysis was used to compare the mean values of different parameters between three groups of Irradiated and controlled samples. The level of significance was set at P<0.05. Results- After exposure to fractional irradiation for 4 weeks, in the zinc phosphate luting cement (Group-A) and glass ionomer luting cement (Group-B), showed a slight decrease in flexural strength. The resin luting cement (Group-C) showed slight increase in flexural strength. Conclusion- Among all the groups, the resin luting cement showed a slight increase in flexural strength when compared to the other luting cement groups after fractional irradiation
Assessing the Assisted Six-Minute Cycling Test as a Measure of Endurance in Non-Ambulatory Patients with Spinal Muscular Atrophy (SMA)

Assessing endurance in non-ambulatory individuals with Spinal Muscular Atrophy (SMA) has been challenging due to limited evaluation tools. The Assisted 6-Minute Cycling Test (A6MCT) is an upper limb ergometer assessment used in other neurologic disorders to measure endurance. To study the performance of the A6MCT in the non-ambulatory SMA population, prospective data was collected on 38 individuals with SMA (13 sitters; 25 non-sitters), aged 5 to 74 years (mean = 30.3; SD = 14.1). The clinical measures used were A6MCT, Revised Upper Limb Module (RULM), Adapted Test of Neuromuscular Disorders (ATEND), and Egen Klassifikation Scale 2 (EK2). Perceived fatigue was assessed using the Fatigue Severity Scale (FSS), and effort was assessed using the Rate of Perceived Exertion (RPE). Data were analyzed for: (1) Feasibility, (2) Clinical discrimination, and (3) Associations between A6MCT with clinical characteristics and outcomes. Results showed the A6MCT was feasible for 95% of the tested subjects, discriminated between functional groups (p = 0.0086), and was significantly associated with results obtained from RULM, ATEND, EK2, and Brooke (p < 0.0001; p = 0.029; p < 0.001; p = 0.005). These findings indicate the A6MCT’s potential to evaluate muscular endurance in non-ambulatory SMA individuals, complementing clinician-rated assessments. Nevertheless, further validation with a larger dataset is needed for broader application.
Short Text, Large Effect: Measuring the Impact of User Reviews on Android App Security & Privacy

Application markets streamline the end-users’ task of finding and installing applications. They also form an immediate communication channel between app developers and their end-users in form of app reviews, which allow users to provide developers feedback on their apps. However, it is unclear to which extent users employ this channel to point out their security and privacy concerns about apps, about which aspects of apps users express concerns, and how developers react to such security- and privacy-related reviews. In this paper, we present the first study of the relationship between end-user reviews and security- & privacy-related changes in apps. Using natural language processing on 4.5M user reviews for the top 2,583 apps in Google Play, we identified 5,527 security and privacy relevant reviews (SPR). For each app version mentioned in the SPR, we use static code analysis to extract permission-protected features mentioned in the reviews. We successfully mapped SPRs to privacy-related changes in app updates in 60.77% of all cases. Using exploratory data analysis and regression analysis we are able to show that preceding SPR are a significant factor for predicting privacy-related app updates, indicating that user reviews in fact lead to privacy improvements of apps. Our results further show that apps that adopt runtime permissions receive a significantly higher number of SPR, showing that runtime permissions put privacy-jeopardizing actions better into users’ minds. Further, we can attribute about half of all privacy-relevant app changes exclusively to third-party library code. This hints at larger problems for app developers to adhere to users’ privacy expectations and markets’ privacy regulations. Our results make a call for action to make app behavior more transparent to users in order to leverage their reviews in creating incentives for developers to adhere to security and privacy best practices, while our results call at the same time for better tools to support app developers in this endeavor.
Effect of Cash Storage on the Financial Performance of Commercial Banks in Kenya

Purpose: The study sought to establish the effect of cash storage and on financial performance of commercial banks of Kenya. Methodology: The research was carried out through a descriptive survey research design. Descriptive design was used because it focused on complex analysis to bring out the correlation of variables. The study population was all the 43 commercial banks registered and licensed to operate in Kenya. These commercial banks formed the unit of analysis. A census was conducted on all the banks. The sampling frame of the survey of the banks was one head of operations and head of finance from each of the 43 commercial banks located in Nairobi County. The target respondents was hence 86. The study used both primary and secondary data for analysis. Inferential analysis techniques including correlation, regression and t-tests were used to achieve the study objectives. SPSS version 21 was used for analysis. Findings: The study findings indicated that the correlation between, cash storage and financial performance is positive. Further results indicated cash storage had a positive significant effect on cash storage and ROA is positive and significant. Unique Contribution to Theory, Practice and Policy: The study was anchored on cash management theory to evaluate the effect of cash storage on the financial performance of Commercial Banks in Kenya. The study recommends that commercial banks and other financial institutions involved in handling of cash should put in place proper reconciliation practices for instance increasing the frequency of reconciling books. The study also recommends that advanced practices of cash storage for instance investing in fire proof safes for storing cash and also in closed circuit television security cameras for surveillance of cash storage areas and also invest in alarm system in cash storage areas and also restricted access to cash storage areas by lock, key, passwords and other security measures so as to reduce fraud arising as a result of poor cash storage practices.
THE GEODYNAMIC SETTING OF LARGE-SCALE METALLOGENESIS IN MAINLAND CHINA, EXEMPLIFIED BY SKARN TYPE GOLD DEPOSITS

This paper summarizes the geological characteristics of seventy skarn-type gold deposits occurred in various tectonic units of China. They include 1 super-large, 19 large and 24 medium-sized, and contain a total resource of approximately 1 000 tons of gold, accounting for 20% of China's gold reserves. This shows that skarn-type gold is one of the most important kinds of gold resources and worth of more attention in geological research and gold exploration. In compiling a distribution map of skarn-type gold deposits, it is found that gold-bearing skarns are sited in collisional orogenic belts, fault-controlled magmatic belts and reactivated cratonic margins. All of the Chinese skarn gold provinces were affected by Phanerozoic collisional orogenesis. On the basis of compiling the data set of isotope ages for skarn-type gold deposits and other kinds of hydrothermal deposits and their related granitoids, combined with a synthesis of geological evolution of different tectonic units, it is revealed that the metallogenesis of skarn-type gold deposits in China always postdated the final oceanic closure or the beginning of inter-continent collision in each tectonic unit by about 50 Ma. This rules out the possibility that these skarn-type gold deposits were formed in a magmatic arc setting resulted from oceanic plate subduction. Linking the common p-T-t path for collisional orogeny to the tectonic evolution of metallogenic provinces in China shows that the large-scale granitic magmatism and metallogenesis in China occurred in a decompression-geothermal increase regime during tectonic transition from collisional compression to extension, instead of post-collisional tectonism. Therefore, the CMF model, which is based on the architecture and dynamic mechanism of collision orogens, can be used to interpret the temporal and spatial distribution and the genesis of the skarn gold deposits in China.
The Effect of Financial Performance and Company Size on Company Value: A Review of Literature Studies

The literature review article on the Effect of Financial Performance and Company Size on Company Value aims to formulate a research hypothesis that evaluates the relationship between these variables in future research. The method for writing this literature review article is based on the literature review research method, with data sources coming from various platforms such as Google Scholar, Mendeley, Semantic Scholar, and other online academic sources. The findings from this literature review article show that financial performance has a significant impact on company value, while company size has no effect on company value.
Diffusion effects in the Belgian fertility transition : space-time analyses at the municipal and individual levels (1887–1934)

Between the late nineteenth century and early twentieth century, couples all around Europe began to deliberately limit their offspring, leading to an unparalleled decline in fertility levels. Even though these transformations affected all European societies, they did not happen for everyone in all places at the same time. Changes in family behaviour typically started in certain groups in specific places and later spread to the rest of the population. The underlying mechanisms of the spread of new fertility trends, however, are still a matter of debate. On the one hand, it could be argued that the determinants of fertility change – such as economic and cultural shifts – do not happen simultaneously everywhere. On the other hand, it has been suggested that there could be something more behind the patterns of change: diffusion processes, via the exchange of ideas and information between people, could affect the spread of new behaviours. The main purpose of this thesis is to investigate the underlying mechanisms of the spread of modern fertility behaviour in Belgium during the fertility transition. To this end, the research relies on a unique body of data gathered from different sources between 1886 and 1934. The datasets offer a high level of spatial and temporal precision and combine macro and micro perspectives. Different quantitative methods are employed in order to investigate the impact of diffusion on the timing, the pace and the geography of fertility decline.
ANALYTIC SOLUTION OF FRACTIONAL ADVECTION DISPERSION EQUATION WITH DECAY FOR CONTAMINANT TRANSPORT IN POROUS MEDIA

Advection and dispersion are the movements of contaminants/solute particles along with ﬂowing groundwater at the seepage velocity in porous media. The aim of this paper is to ﬁnd concentration of contaminant in ﬂowing groundwater using fractional advection dispersion equation with decay involving Hilfer derivative with respect to time. Time fractional advection-dispersion equation describe particle’s motion with memory in time. The solution of time fractional advection dispersion equation with decay is obtained in terms of Mittag-Leﬄer function and Green function. The eﬀect of the decay is to reduce mass and concentration of the solution, which is a function of time and space variable.
Sedimentary features reveal transport paths for Holocene sediments on the Kristianstad coastal plain, SE Sweden

Abstract We have investigated coastal and aeolian deposits on the Kristianstad plain in southernmost Sweden by a combination of methods that has yielded data on sedimentary features such as grain-size variations, shape and character of quartz grain surfaces (determined in light microscope and scanning electron microscope), and mineralogical composition. Such sedimentary techniques have been not applied to coastal deposits in this part of the Baltic Sea region before. The littoral, foredune and parabolic dune sands are sedimentologically similar, only a slight grain-size transformation by aeolian processes in the foredune was observed. Sand in straight-crested dunes, on the other hand, originates from immature glaciolacustrine sediments, seen e.g. through the increase in mineral maturity during active aeolian transport. Finally, a palaeosol, occuring below an aeolian cover, carries both aeolian and glaciolacustrine sedimentary signals.
HPLC method for quantifying verbascoside in Stizophyllum perforatum and assessment of verbascoside acute toxicity and antileishmanial activity

We report the chemical composition of the crude leaf extracts obtained from Stizophyllum perforatum (Cham.) Miers (Bignoniaceae), a simple high-performance liquid chromatography–diode array detection (HPLC-DAD) method based on mangiferin as an internal standard to quantify verbascoside, and the verbascoside acute oral toxicity and antileishmanial activity. HPLC–high-resolution mass spectrometry–DAD (HPLC–HRMS–DAD) analyses of the crude ethanol S. perforatum leaf extracts (CE-1 and CE-2) revealed that verbascoside was the major constituent in both extracts. CE-1 was purified, and verbascoside and casticin, among other compounds, were isolated. The developed HPLC-DAD method was validated and met the required standards. Investigation of the CE-2 acute toxicity indicated a lethal dose (LD50) greater than 2,000 mg/kg of body weight. Both CE-1 and CE-2 exhibited antileishmanial activity. The isolated compounds, verbascoside and casticin, also displayed antileishmanial activity with effective concentrations (IC50) of 6.23 and 24.20 µM against promastigote forms and 3.71 and 18.97 µM against amastigote forms of Leishmania amazonensis, respectively, but they were not cytotoxic to J774A.1 macrophages. Scanning electron microscopy of the L. amazonensis promastigotes showed that the parasites became more rounded and that their plasma membrane was altered in the presence of verbascoside. Additionally, transmission electron microscopy demonstrated that vacuoles emerged, lipids accumulated, kinetoplast size increased, and interstitial extravasation occurred in L. amazonensis promastigotes exposed to verbascoside. These findings suggest that S. perforatum is a promising candidate for further in vivo investigations against L. amazonensis.
Comparing the linear and nonlinear buoyancy-driven circulation

The buoyancy-driven circulation is studied in an idealized domain using two models, one based on the linearized planetary geostrophic equations and a fully nonlinear GCM. The surface buoyancy is specified (relaxed) to a chosen function of latitude in the linear (nonlinear) model. The models yield similar baroclinic flow in the interior, where the surface velocities are primarily zonal, and near the southern boundary, where a westward surface flow feeds the western boundary current (WBC). They differ however in the north. While the linear model has westward surface flow of limited vertical extent near the northern wall, the GCM has baroclinic flow which extends to the bottom with eastward surface velocities. The difference is due to convection, which weakens the stratification in the nonlinear model, amplifying the thermal wind transport associated with the surface buoyancy gradient. The WBC flow in the GCM feeds this, with northward surface flow over its entire length (as seen in nearly all previous similar studies). This in turn determines the meridional overturning circulation, since the WBC accounts for the largest meridional velocities. Roughly half the upwelling occurs in the WBC in the GCM and half in the interior, while the upwelling occurs in the interior and near the southern wall in the linear model. The study highlights the role of convection in modifying the response to the surface buoyancy gradient.
Dynamic Interactions between Diarrhoeagenic Enteroaggregative Escherichia coli and Presumptive Probiotic Bacteria: Implications for Gastrointestinal Health

This study delves into the temporal dynamics of bacterial interactions in the gastrointestinal tract, focusing on how probiotic strains and pathogenic bacteria influence each other and human health. This research explores adhesion, competitive exclusion, displacement, and inhibition of selected diarrhoeagenic Escherichia coli (D-EAEC) and potential probiotic strains under various conditions. Key findings reveal that adhesion is time-dependent, with both D-EAEC K2 and probiotic L. plantarum FS2 showing increased adhesion over time. Surprisingly, L. plantarum FS2 outperformed D-EAEC K2 in adhesion and exhibited competitive exclusion and displacement, with inhibition of adhesion surpassing competitive exclusion. This highlights probiotics’ potential to slow pathogen attachment when not in competition. Pre-infecting with L. plantarum FS2 before pathogenic infection effectively inhibited adhesion, indicating probiotics’ ability to prevent pathogen attachment. Additionally, adhesion correlated strongly with interleukin-8 (IL-8) secretion, linking it to the host’s inflammatory response. Conversely, IL-8 secretion negatively correlated with trans-epithelial electrical resistance (TEER), suggesting a connection between tight junction disruption and increased inflammation. These insights offer valuable knowledge about the temporal dynamics of gut bacteria interactions and highlight probiotics’ potential in competitive exclusion and inhibiting pathogenic bacteria, contributing to strategies for maintaining gastrointestinal health and preventing infections.