Miracle-dz/UniFAR-FTUs huggingface dataset:
A UNIFIED WALL-BOUNDARY CONDITION FOR THE LATTICE BOLTZMANN METHOD AND ITS APPLICATION TO FORCE EVALUATION

A unified wall-boundary condition for the pressure-based lattice Boltzmann method (LBM) is pro- posed. The present approach is developed from the direct-forcing technique in the immersed boundary method and is derived from the equilibrium pressure distribution function. The proposed method can handle many kinds of wall boundaries, such as fixed wall and moving wall boundaries, in the same way. It is found that the new method has the following advantages: (1) simple in concept and easy to imple- ment, (2) higher-order accuracy, (3) mass conservation, and (4) a stable and good convergence rate. Based on this wall-boundary condition, if a solid wall is immersed in a fluid, then by applying Gauss's theorem, the formulas for computing the force and torque acting on the solid wall from fluid flow are de- rived from the volume integrals over the solid volume instead of from the surface integrals over the solid surface. Based on the pressure-based LBM, inlet and outlet boundary conditions are also proposed. The order of accuracy of the proposed boundary condition is demonstrated with the errors of the velocity field, wall stress, and gradients of velocity and pressure. The steady flow past a circular cylinder is sim- ulated to demonstrate the efficiency and capabilities of the proposed unified method.
In situ formed scaffold with royal jelly-derived extracellular vesicles for wound healing

Background: Safe and effective wound healing can be a major clinical challenge. Inflammation and vascular impairment are two main causes of inadequate wound healing. Methods: Here, we developed a versatile hydrogel wound dressing, comprising a straightforward physical mixture of royal jelly-derived extracellular vesicles (RJ-EVs) and methacrylic anhydride modified sericin (SerMA), to accelerate wound healing by inhibiting inflammation and promoting vascular reparation. Results: The RJ-EVs showed satisfactory anti-inflammatory and antioxidant effects, and significantly promoted L929 cell proliferation and migration in vitro. Meanwhile, the photocrosslinked SerMA hydrogel with its porous interior structure and high fluidity made it a good candidate for wound dressing. The RJ-EVs can be gradually released from the SerMA hydrogel at the wound site, ensuring the restorative effect of RJ-EVs. In a full-thickness skin defect model, the SerMA/RJ-EVs hydrogel dressing accelerated wound healing with a healing rate of 96.8% by improving cell proliferation and angiogenesis. The RNA sequencing results further revealed that the SerMA/RJ-EVs hydrogel dressing was involved in inflammatory damage repair-related pathways including recombinational repair, epidermis development, and Wnt signaling. Conclusion: This SerMA/RJ-EVs hydrogel dressing offers a simple, safe and robust strategy for modulating inflammation and vascular impairment for accelerated wound healing.
Regional Model Life Tables and Stable Populations

The intention of this volume is to make available to demographers and statisticians extended tabulations that will expedite a wide range of demographic analysis and estimation of population statistics. The tables presented are of 2 principal types: model life tables and stable populations. This volume makes available a set of model life tables somewhat different and more extensive than the United Nations collection and a large number--almost 5000--of stable populations with a variety of associated parameters including the age distributions of deaths. The 3 chapters of the introductory text present a general description of model life tables and stable populations a brief account of the methods of calculation used to construct the tables and illustrative uses of the tables and explanations of the terms and symbols employed. The life tables presented were calculated on the basis of the joint use of data originating from continuous registration and from an enumeration of the population at a given time. A basic collection was obtained containing 326 male and 326 female life tables. The 4 families of life tables presented in this volume are the result of a search for several distinctive patterns in the variation of mortality rates with age. 9 principal sets of correlations were experimented with for each sex: tables before 1870; tables for Russia and certain Balkan areas; tables for selected Central European areas; tables for Scandinavian countries; tables for Spain Portugal and Southern Italy; tables for Switzerland; tables for countries with reliable data and previously not included; tables reflecting mortality when there is an unusually high incidence of tuberculosis; and modern tables based on relatively inaccurate data primarily from Asia Africa and Latin America.
The Synergy between Glutathione and Phenols—Phenolic Antioxidants Repair Glutathione: Closing the Virtuous Circle—A Theoretical Insight

Glutathione (GSH) and phenols are well-known antioxidants, and previous research has suggested that their combination can enhance antioxidant activity. In this study, we used Quantum Chemistry and computational kinetics to investigate how this synergy occurs and elucidate the underlying reaction mechanisms. Our results showed that phenolic antioxidants could repair GSH through sequential proton loss electron transfer (SPLET) in aqueous media, with rate constants ranging from 3.21 × 106 M−1 s−1 for catechol to 6.65 × 108 M−1 s−1 for piceatannol, and through proton-coupled electron transfer (PCET) in lipid media with rate constants ranging from 8.64 × 106 M−1 s−1 for catechol to 5.53 × 107 M−1 s−1 for piceatannol. Previously it was found that superoxide radical anion (O2•−) can repair phenols, thereby completing the synergistic circle. These findings shed light on the mechanism underlying the beneficial effects of combining GSH and phenols as antioxidants.
The Impact of Statistical Distributions of Colours on Colour Category Acquisition

Different accounts have been proposed to explain the remarkable crosscultural similarities of human colour categories. One of these accounts, known as empiricism, places the burden of the explanation on the statistical distribution of colours in the shared environment we live in. It has been claimed that this factor is essential for the nature of human colour categories and that it is even capable to account for the evolution of colour categories as observed in human cultures. We present a computational model to verify this hypothesis, which improves on previous work by Yendrikhovskij (2001a). Our results suggest that the chromatic environment does not fully explain the nature of human colour categories, however the distribution of colours in the environment does bias the acquisition of colour categories. We suggest how culture and specifically language might account for the observed nature of human colour categories.
Transvaginal ultrasonography predictive model for the detection of pelvic congestion syndrome

Background The diagnosis of pelvic congestion syndrome (PCS) remains a challenge given the lack of universally accepted criteria. Although venography (VG) is the current gold standard for the diagnosis of PCS, non-invasive techniques like transvaginal ultrasonography (TVU) appear to be a valid alternative. The aim of this study was to design a predictive model for the venographic diagnostic of PCS using the parameters identified by TVU in patients with clinical suspicion of PCS, in order to individually assess the need to perform an invasive diagnostic and therapeutic technique such as VG. Methods An observational and cross-sectional prospective study was conducted including 61 consecutively recruited patients with clinical suspicion of PCS, who were referred by the Pelvic Floor, Gynecology and Vascular Surgery Units, who were distributed in two groups: 18 belonging to the normal group and 43 to the PCS’s group. We implemented and compared 19 binary logistic regression models, including the parameters that showed statistical significance in the prior univariate analysis. We evaluated individual predictive values with a receiver operating characteristic (ROC) curve and the area under the curve (AUC). Results The selected model, based on the presence of pelvic veins or venous plexus of 8 mm or larger, observed by transvaginal ultrasound, had an AUC of 0.79 (95% CI: 0.63–0.96; P<0.001), with a sensitivity of 0.90 and specificity of 0.69, while the VG had a sensitivity of 86.05%, a specificity of 66.67%, and a positive predictive value of 86.05%. Conclusions This assessment presents a feasible alternative that could potentially be added to our usual gynecological practice.
Multi-bump solutions for Schrödinger equation involving critical growth and potential wells

In this paper, we consider the following Schrodinger equation with critical growth $$-\Delta u+(\lambda a(x)-\delta)u=|u|^{2^*-2}u \quad \hbox{ in } \mathbb{R}^N, $$ where $N\geq 5$, $2^*$ is the critical Sobolev exponent, $\delta>0$ is a constant, $a(x)\geq 0$ and its zero set is not empty. We will show that if the zero set of $a(x)$ has several isolated connected components $\Omega_1,\cdots,\Omega_k$ such that the interior of $\Omega_i (i=1, 2, ., k)$ is not empty and $\partial\Omega_i (i=1, 2, ., k)$ is smooth, then for any non-empty subset $J\subset \{1,2,\cdots,k\}$ and $\lambda$ sufficiently large, the equation admits a solution which is trapped in a neighborhood of $\bigcup_{j\in J}\Omega_j$. Our strategy to obtain the main results is as follows: By using local mountain pass method combining with penalization of the nonlinearities, we first prove the existence of single-bump solutions which are trapped in the neighborhood of only one isolated component of zero set. Then we construct the multi-bump solution by summing these one-bump solutions as the first approximation solution. The real solution will be obtained by delicate estimates of the error term, this last step is done by using Contraction Image Principle.
A Generalization of Commutative and Alternative Rings

In [3] Schafer has defined generalized standard rings as rings satisfying the identities (1) (2) (3) and observed that these identities imply (y,y, (x, z)) = 0 and if the characteristic is not three, (x, y, x 2) = 0. Schafer determined the structure of simple, finite-dimensional generalized standard algebras of characteristic not two or three by showing that they must be either commutative, Jordan, or alternative. Previously one of us [2] had studied accessible rings, which are defined by the identities (x,y,z) + (z,x,y) – (x,z,y) = 0 and ((w,x), y,z) = 0.
A boat’s afterlife: multiple translations of migratory debris

Over the past decade, images of boats crossing or sinking in the Mediterranean have become extremely familiar to European publics. What is less familiar is the processes through which those boats are re-purposed, becoming artistic or even commodified goods once they reach a port of landing. Caught between being considered waste and valuable objects, these debris have been moved and re-purposed with scarce acknowledgement of the political work that these practices perform. This paper argues that practices of translation transform objects into waste or valuables and reveal crucial fault lines in the politics of migration – such as the limits of a politics of posthumous commemoration and the de-politicisation of border deaths. Translation works through a wide variety of professional practices and the assembling of value, which informs the staging of materials as waste or as valuables. By analysing the case of the art installation Barca Nostra, this article rethinks the role of migratory debris and the multiplicity of meaning attributed to them by highlighting how they must be read simultaneously as waste and objects of value to fully understand how practices of translation contribute to the de-politicisation of border deaths, leaving state violence in the Mediterranean unchallenged.
Wide Awake Local Anesthesia No Tourniquet Surgery of Carpal Tunnel Syndrome: Patients’ Experience and Recall Bias in a Day-Care Setting

Background and Objective: Wide-Awake Local Anesthesia No Tourniquet (WALANT) is a technique of local anesthesia commonly used in the surgical treatment of a wide variety of conditions affecting the upper extremity, including Carpal Tunnel Syndrome (CTS). The recent retrospective studies investigated patient experiences in a wide variety of hand disorder-related cases. The aim of our study is to evaluate patient satisfaction regarding open surgical treatment for CTS using the WALANT technique. Material and Methods: we enrolled 82 patients with CTS without medical record of surgical treatment for CTS. For WALANT, a hand surgeon used a combination of 1:200,000 epinephrine, 1% lidocaine, and 1 mL 8.4% sodium bicarbonate solution without tourniquet application and sedating the patient. All patients were treated in a day-care setting. For assessment of patient experience, Lalonde’s questionnaire was adapted. Participants completed survey twice: one month and six months after the surgical treatment was performed. Results: the median pre-operative pain score for all patients was 4 (range 0–8) after one month and 3 (range 1–8) after six months. The median intraoperative pain score for all patients was 1 (range 0–8) after one month and 1 (range 1–7) after six months. The median post-operative pain score for all patients was 3 (range 0–9) after one month and 1 (range 0–8) after six months. More than half (61% after one month and 73% after six months) of the patients responded by stating that their real experience of WALANT was better than their initial expectations. An absolute majority of patients (95% after one month and 90% after six months) would recommend WALANT treatment to their relatives. Conclusions: overall, patient satisfaction with treatment for CTS using WALANT is high. Furthermore, complications related to the performed treatment and persistent post-operative pain could be associated with more reliable patient recall of this healthcare intervention. A longer period of time between intervention and assessment of patient experience could possibly be a reason for recall bias.
Modeling Temperature-Dependent Behavior of Soft Clay

AbstractIn this study, an anisotropic thermal-elastic-plastic (TEP) constitutive model is developed for soft clays. Two yield surfaces, namely the current yield surface and reference yield surface, are adopted to characterize the development of plastic volumetric strain (i.e., the unique internal variable of the two surfaces) due to either mechanical or thermal loading. The model is formulated based on the framework of the Modified Cam-Clay model, with only two additional parameters introduced (i.e., α and θ), to account for stress-induced anisotropy and thermal-induced translation of compression curves, respectively. Based on the model, a simplified equation is proposed to quantify the effect of drained heating on the undrained shear strength of clay. The predictive capability of the proposed model and the simplified equation for undrained shear strength are verified against published results of temperature-controlled triaxial tests on soft clay. By assessing seven different types of clays, the thermal-r.
Histologic Analysis of Idiopathic Pulmonary Fibrosis by Morphometric and Fractal Analysis

Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive fibrotic lung disorder, ultimately leading to respiratory failure and death. Despite great research advances in understanding the mechanisms underlying the disease, its diagnosis, and its treatment, IPF still remains idiopathic without known biological or histological markers able to predict disease progression or response to treatment. The histologic hallmark of IPF is usual interstitial pneumonia (UIP), with its intricate architectural distortion and temporal inhomogeneity. We hypothesize that normal lung alveolar architecture can be compared to fractals, such as the Pythagoras tree with its fractal dimension (Df), and every pathological insult, distorting the normal lung structure, could result in Df variations. In this study, we aimed to assess the UIP histologic fractal dimension in relationship to other morphometric parameters in newly diagnosed IPF patients and its possible role in the prognostic stratification of the disease. Clinical data and lung tissue specimens were obtained from twelve patients with IPF, twelve patients with non-specific interstitial pneumonia (NSIP), and age-matched “healthy” control lung tissue from patients undergoing lung surgery for other causes. Histology and histomorphometry were performed to evaluate Df and lacunarity measures, using the box counting method on the FracLac ImageJ plugin. The results showed that Df was significantly higher in IPF patients compared to controls and fibrotic NSIP patients, indicating greater architectural distortion in IPF. Additionally, high Df values were associated with higher fibroblastic foci density and worse prognostic outcomes in IPF, suggesting that Df may serve as a potential novel prognostic marker for IPF. The scalability of Df measurements was demonstrated through repeated measurements on smaller portions from the same surgical biopsies, which were selected to mimic a cryobiopsy. Our study provides further evidence to support the use of fractal morphometry as a tool for quantifying and determining lung tissue remodeling in IPF, and we demonstrated a significant correlation between histological and radiological Df in UIP pattern, as well as a significant association between Df and FF density. Furthermore, our study demonstrates the scalability and self-similarity of Df measurements across different biopsy types, including surgical and smaller specimens.
Generalized Stirling Numbers, Convolution Formulae and p, q-Analogues

Abstract In this paper, we study two generalizations of the Stirling numbers of the first and second kinds, inspired from their combinatorial interpretation in terms of 0-1 tableaux. They are the 𝔄-Stirling numbers and the partial Stirling numbers. In particular, we give a q and a p, q-analogue of convolution formulae for Stirling numbers of the second kind, due to Chen and Verde-Star, and we extend these formulae to Stirling numbers of the first kind. Included in this study are the a, d-progressive Stirling numbers, corresponding to 0-1 tableaux with column lengths from an arithmetic progression ﹛a + id﹜i≥0.
Calibration of Low-cost Sensors for Measurement of Indoor Particulate Matter Concentrations via Laboratory/Field Evaluation

Recently, low-cost sensors (LCSs) have been widely used in monitoring particulate matter (PM) mass concentrations. Maintaining the accuracy of the sensors is important and requires rigorous calibration and performance evaluation. In this study, two commercial LCSs, Plantower PMS3003 and Plantower PMS7003, were evaluated in the laboratory and in the field using a reference-grade PM monitor (GRIMM 11-D). Laboratory evaluation was conducted with polystyrene latex (PSL) particles in a 1 m 3 chamber at 20 ° C with a relative humidity of 20%. Each LCS indicated higher mass concentrations than GRIMM 11-D for small-sized PSL particles (0.56 µ m); however, the LCSs indicated lower mass concentrations than GRIMM 11-D for PSL particles larger than 0.56 µ m. In addition, the difference in mass concentrations between the LCS and GRIMM 11-D became higher with particle sizes greater than 0.56 µ m. Nonetheless, a high correlation (R 2 > 0.9) between each LCS and GRIMM 11-D was obtained. Field evaluation was conducted at Yonsei University (Seoul, South Korea) from February 12 to March 31, 2022. The LCSs showed generally higher PM mass concentrations than GRIMM 11-D; however, some data points of the LCSs revealed different trends. We observed that outdoor PM 10 /PM 2.5 and relative humidity had notable impacts on the LCS data; in addition, LCS sensitivity depended on whether the PM concentration was low or high. Based on these observations, regression-based calibration models were constructed using the selected independent variables (outdoor PM 10 /PM 2.5 and relative humidity) after dividing the PM concentration into low and high sections. Consequently, the accuracy of the LCSs was significantly enhanced. Therefore, using LCSs with the calibration models can replace the use of expensive reference PM monitors, resulting in cost savings.
Low Prevalence of HSV-1 and Helicobacter pylori in HNSCC and Chronic Tonsillitis Patients Compared to Healthy Individuals

Recent studies identified viral and bacterial factors, including HSV-1 and H. pylori, as possible factors associated with diseases such as chronic tonsillitis and cancers, including head and neck squamous cell carcinoma (HNSCC). We assessed the prevalence of HSV-1/2 and H. pylori in patients with HNSCC, chronic tonsillitis, and healthy individuals using PCR after DNA isolation. Associations were sought between the presence of HSV-1, H. pylori, and clinicopathological and demographic characteristics and stimulant use. HSV-1 and H. pylori were most frequently identified in controls (HSV-1: 12.5% and H. pylori: 6.3%). There were 7 (7.8%) and 8 (8.6%) patients with positive HSV-1 in HNSCC and chronic tonsillitis patients, respectively, while the prevalence of H. pylori was 0/90 (0%) and 3/93 (3.2%), respectively. More cases of HSV-1 were observed in older individuals in the control group. All positive HSV-1 cases in the HNSCC group were associated with advanced tumor stage (T3/T4). The prevalence of HSV-1 and H. pylori was highest in the controls compared to HNSCC and chronic tonsillitis patients, which indicates that the pathogens were not risk factors. However, since all positive HSV-1 cases in the HNSCC group were observed only in patients with advanced tumor stage, we suggested a possible link between HSV-1 and tumor progression. Further follow-up of the study groups is planned.
Changes in and Predictors of HIV among People Who Inject Drugs in Mizoram, Northeast India, from 2007 to 2021

This study aimed to examine the changes in and predictors of the human immunodeficiency virus (HIV) among people who inject drugs (PWID) in Mizoram, Northeast India, over a period of 15 years (2007–2021). A sample of 14783 PWID was extracted from the Targeted Intervention (TI) services under the Mizoram State AIDS Control Society (MSACS). A chi-square test was used to compare the differences in HIV prevalence across the three 5-year periods, and a multiple logistic regression analysis was used to determine predictors after adjusting for sociodemographic, injecting and sexual behaviours. The results showed that compared to 2007–2011, HIV prevalence was almost three times higher in 2012–2016 (AOR 2.35; 95% CI 2.07–2.66) and almost two times higher in 2017–2021 (AOR 1.41; 95% CI 1.24–1.59). The results suggest that participants who were females (AOR 2.35; 95% CI 2.07–2.66), married (AOR 1.13; 95% CI 1.00–1.27), separated/divorced/widowed (AOR 1.74; 95% CI 1.54–1.96), of middle school level education (AOR 1.24; 95% CI 1.06–1.44), sharing needles/syringes (AOR 1.78; 95% CI 1.61–1.98) and receiving a regular monthly income were positively associated with HIV infection. Condom use with a regular partner (AOR 0.77; 95% CI 0.70–0.85) was high among PWID. Despite targeted interventions under MSACS to reduce HIV in Mizoram, the prevalence of HIV/AIDS among PWID remained high between 2007 and 2021. Policymakers and stakeholders should tailor future interventions based on the factors identified in this study that are associated with HIV infection. Our findings highlight the importance of socio-cultural factors in HIV epidemiology among PWID in Mizoram.