Miracle-dz/UniFAR-FTUs huggingface dataset:
Mycofumigation with the endophytic fungi Fusarium proliferatum (Matsushima) Nirenberg and Diaporthe sp. for the control of banana and mango anthracnose

Banana and mango are the top commodities in the Philippines that are traded worldwide however, fungal diseases such as anthracnose affect their yield and quality. Environmentally sound control strategies have been explored and one of these is mycofumigation using fungal endophytes. This alternative approach is understudied in the Philippines, hence, the study aimed to evaluate the mycofumigation potential of fungal endophytes collected from Mt. Makiling, Luzon, Philippines and their pathogenicity to banana and mango fruits. In vitro and in vivo mycofumigation assays were conducted with a completely randomized design layout with triplicates per treatment under laboratory conditions. The fungal endophytes used as mycofumigants, Diaporthe sp. and Fusarium proliferatum, were comparatively effective in controlling the anthracnose of banana and mango. The mycelial growth for in vitro assay of Colletotrichum musae and Colletotrichum gloeosporioides were significantly reduced compared to the control when exposed to volatile organic compounds produced by the fungal endophytes. In addition, the results of the in vivo mycofumigation assay against C. musae showed Diaporthe sp. had a significantly higher inhibition rate (93%) than F. proliferatum (67%) when grown on potato dextrose agar plates. The bioefficacy of the Diaporthe sp. and F. proliferatum was improved when grown on peanut and corn seed substrates with a reduction of banana and mango anthracnose severity ranging from 82 to 100%. Cultures grown on corn substrate performed better than those grown on peanut. Pathogenicity tests also revealed that these endophytic fungi did not cause disease in the banana or mango fruits indicating their potential as good biocontrol agents against C. musae and C. gloeosporioides.
The drivers of the project of finance interest rate in the ASEAN-4 countries

This paper highlights the significant aspects of the project finance theme in terms of the prospective return of the infrastructure project, the risk mitigation feature of project finance in addressing various risks, and future stability requirements in achieving the future country growth target through infrastructure investment. This paper attempts to investigate the determinants of the total interest rate charged on project finance. We found that the critical risk factor does not affect the interest rate, because the critical risk factor with the proxy of political stability and government effectiveness does not affect the interest of project financing loans due to the characteristics of ASEAN-4 countries.
Challenges in Emerging Adulthood Related to the Impact of Childhood Bullying Victimization

Findings from interviews with 15 emerging adults (M age = 29.00, SD = .37) subjected to bullying victimization as children and suffering from poor psychological health in emerging adulthood revealed experiences of a very long duration of victimization, coping through adaptation to the bullying, and experiences of not receiving help from school personnel. Many participants described experiences of depression, anxiety, and even suicidal thoughts during the school-years victimization. They perceived several direct long-term consequences of the victimization in emerging adulthood: feelings of insecurity; actively avoiding social situations; an identity formed into viewing oneself as worthless; and body-image problems. Additionally, many of them still felt anger towards school personnel who they remembered as not stopping the victimization. A longitudinal and prospective design enabled insights into victims’ experiences of both the childhood victimization as well as perceived long-term consequences on their emerging adulthood – and into how the victims experience that these aspects might be related.
Effectiveness of a nurse-led Mindfulness-based Tai Chi Chuan (MTCC) program on Posttraumatic Growth and perceived stress and anxiety of breast cancer survivors

ABSTRACT Background With the development of positive psychology, posttraumatic growth research on cancer patients has attracted increasing attention from researchers. It is immensely important to effectively increase the posttraumatic growth level of cancer patients and improve their quality of life. Objectives To investigate the effectiveness of a nurse-led mindfulness-based Tai Chi Chuan (MTCC) programme for increasing posttraumatic growth (PTG) and decreasing the perceived stress and anxiety of breast cancer survivors. Methods A RCT was conducted. Participants were randomly assigned to either the MTCC group or the control group. The programme included 59 women with stage I–III breast cancer. Participants in the intervention group participated in a nurse-led 8-week, twice a week, one-hour per day mindfulness-based exercise programme. The effectiveness of the intervention was measured three times (T1 – before intervention; T2 – after intervention; T3 – one year after intervention) using validated scales, including the PTG inventory (PTGI), Perceived Stress Scale (PSS), and Self-rating Anxiety Scale (SAS). A repeated-measure analysis of variance model was used to analyse the data. Results Compared with the wait-list control group, the PTG level in the MTCC group was much higher after the 8-week intervention and the follow-up (F = 374.98, P < .000). The results showed that MTCC increased the level of PTG, and the effect persisted 1 year after intervention. In addition, PSS (F = 55.22, P < .000) and SAS (F = 148.92, P < .000) scores were significantly decreased at T2 and T3. Conclusion The research preliminarily revealed that the MTCC programme was simple, effective, and more suitable to clinical nurses which should be recommended to cancer survivors to promote their recovery. HIGHLIGHTS The posttraumatic growth level of breast cancer survivors may decrease as time goes on. A nurse-led MTCC programme facilitates significant improvements in the posttraumatic growth level of breast cancer survivors.
VIBROACOUSTIC MODELING OF A LAUNCH VEHICLE PAYLOAD FAIRING FOR ACTIVE ACOUSTIC CONTROL

Low frequency active acoustic attenuation is examined for the payload fairing of a representative small launch vehicle. The feasibility of using structural sensors and actuators for active acoustic control is assessed with a numerical model of the fairing. The results of the numerical analysis indicate that broadband damping decreases the interior overall sound pressure level between 4 dB and 10 dB, depending on the amount of structural damping that is added to the vibration modes. Singular value analyses demonstrate that point force actuators and in-plane strain actuators have the control authority for active acoustic control. Control studies indicate that local velocity feedback reduces the average vibration level of the fairing by roughly 50%, and that the force levels required of the control system are within the range of conventional point force and piezoceramic actuators.
EFFECT OF USING SOME POLLINATORS ON PRODUCTIVITY OF SOME OLIVE CULTIVARS

The present study was carried out during two successive growing seasons 2014 and 2015 in a private orchard located at Cairo-Alexandria desert road, 64 km from Cairo, to evaluate the efficiency of pollinator on productivity and quality attributes of eight olive cultivars, namely Aggizi, Dolce, Kalamata, Maraki, Coratina, koroneiki, Picual and Manzanillo. Ten year old olive trees, grown in sandy soil, planted at 6 X 3 meters apart and irrigated by the drip irrigation system were used for this investigation. The results revealed that, there were differences in the onset and duration of flowering among the studied cultivars in both seasons. The earliest cultivar in flowering was Aggizi, while the latest cultivar in this respect was Kalamata Cv. in both seasons. Regarding flowering duration, it was observed that the studied cultivars overlapped in their blooming period where it is varied between 15 and 20 days in 2014 and 14-18 days in 2015. The highest perfect flower percentage was observed in Dolce and Coratina Cvs. With respect to self-incompatibility index, Aggizi, Dolce, Maraki and Koroneiki were self-compatible. Then, Picual and Coratina Cvs. recorded partially selfincompatible, whereas, Kalamata and Manzanillo Cvs. recorded higher degree of selfincompatibility,Cross pollination induced the best results with regard to fruit set %, and fruit weight and oil content in most olive cultivars. It can be recommended that, the suitable pollinator for each cultivar were as follows: Maraki and Aggizi were good pollinators for each other, Koroneiki for Dolce, Manzanillo and Picual. Finally, Dolce was a good pollinator for Kalamata, Coratina and Koroneiki.
Attitude Compensation Control for Quadrotor Under Partial Loss of Actuator Effectiveness

In this paper, an augmented fault tolerant attitude control system is presented to address the problem of attitude adjustment for a quad-rotor unmanned aerial vehicle with inertia parameter uncertainties, the external disturbance and the partial loss of actuator effectiveness. To tackle system uncertainty and actuator faults, a fixed time compensation controller is developed based on adaptation mechanism combing with a monitor strategy and Nussbaum gain technique. Robust compensation algorithms under the proposed closed loop system structure are derived in the sense of Lyapunov stability analysis such that the attitude tracking-errors converge to a prescribed compact set in a fixed time. Finally, the simulation results demonstrate the effectiveness of the proposed controller.
Emergence of High Prevalence of Extended-Spectrum Beta-Lactamase and Carbapenemase-Producing Enterobacteriaceae Species among Patients in Northwestern Ethiopia Region

Background World Health Organization identified some Enterobacteriaceae as superbugs because of their high production and spread of extended-spectrum beta-lactamases (ESBL) and carbapenemases. Moreover, their resistance against commonly prescribed antibiotics left few choices of drugs to treat infection. This study is aimed at determining the magnitude of ESBL and carbapenemase-producing Enterobacteriaceae pathogens and their antimicrobial resistance pattern. Materials and Methods A hospital-based cross-sectional study was carried out from February to April 2019 in the Northwestern Ethiopia region. A total of 384 patients presumptive for bacterial infections were conveniently enrolled in the study. Specimens were collected and processed following standard bacteriological procedures. Drug susceptibility tests were performed using disk diffusion technique. ESBL and carbapenemase enzymes were tested by double disk diffusion and modified carbapenem inhibition methods, respectively. The data obtained were analyzed using SPSS version 22 software, and descriptive statistics were summarized in tables and graphs. Results Out of 384 clinical specimens processed 100 (26%) were culture positive for Enterobacteriaceae. The proportion of Enterobacteriaceae infection was relatively higher among in-patients 86 (32.6%) than out-patients 14 (11.7%). Overall, Escherichia coli 35 (9.1%) was the leading isolate followed by Klebsiella pneumoniae 31 (8.1%). Klebsiella pneumoniae 15 (15.6%) was the most frequent isolate from bloodstream infection and is the leading isolate from intensive care unit patients 15 (38.3%). Overall, 44 (44%) of Enterobacteriaceae were extended-spectrum beta-lactamase producers. Among them, Citrobacter spp. was the leading one 4 (80%) followed by Enterobacter cloacae 6 (60%) and K. pneumoniae 18 (58.1%). Furthermore, 6 (6%) of Enterobacteriaceae were carbapenemase-producers, in which 5 (50%) of E. cloacae and 3 (9.7%) of K. pneumoniae had highest percentage. Conclusions. ESBL and carbapenemase-producing isolates of Enterobacteriaceae are alarmingly spreading in the study area. Thus, improving the infection prevention strategy and further screening at the national level is recommended to develop the optimal use of antibiotics.
Attention-Based Multimodal Image Feature Fusion Module for Transmission Line Detection

Transmission line (TL) inspection is important for ensuring a stable supply of electricity to rural areas. Currently, there are several TL detection approaches based on computer vision; however, they have limitations owing to background clutter in visible light images. This article presents a novel multimodal image feature fusion module that utilizes both visible light and infrared images to enhance the TL-detection performance. The proposed module consists of a multibranch feature extraction (MFE) block followed by a channelwise attention (CA) block. The first block extracts the representative features of each modal input using multiple branches. The outputs of the MFE block are jointly aggregated into an attention vector in the CA block. Finally, the attention vector recalibrates each input feature of the proposed module. To reduce the number of additional parameters due to the insertion of the module, we introduced a channel-shrink factor in the MFE block and utilized a $1\times {1}$ convolution in the CA block. Comparison experiments with various augmented conditions of day, night, fog, and snow were conducted on a real-world dataset, which we constructed by visible light and infrared images. The results showed that the proposed module outperformed not only the case of single modal input but also the state-of-the-art fusion methods, regardless of the baseline networks. Additionally, the proposed module showed effectiveness in terms of capacity when the baseline network has a large number of weight parameters.
A Major Intestinal Catabolite of Quercetin Glycosides, 3-Hydroxyphenylacetic Acid, Protects the Hepatocytes from the Acetaldehyde-Induced Cytotoxicity through the Enhancement of the Total Aldehyde Dehydrogenase Activity

Aldehyde dehydrogenases (ALDHs) are the major enzyme superfamily for the aldehyde metabolism. Since the ALDH polymorphism leads to the accumulation of acetaldehyde, we considered that the enhancement of the liver ALDH activity by certain food ingredients could help prevent alcohol-induced chronic diseases. Here, we evaluated the modulating effects of 3-hydroxyphenylacetic acid (OPAC), the major metabolite of quercetin glycosides, on the ALDH activity and acetaldehyde-induced cytotoxicity in the cultured cell models. OPAC significantly enhanced the total ALDH activity not only in mouse hepatoma Hepa1c1c7 cells, but also in human hepatoma HepG2 cells. OPAC significantly increased not only the nuclear level of aryl hydrocarbon receptor (AhR), but also the AhR-dependent reporter gene expression, though not the nuclear factor erythroid-2-related factor 2 (Nrf2)-dependent one. The pretreatment of OPAC at the concentration required for the ALDH upregulation completely inhibited the acetaldehyde-induced cytotoxicity. Silencing AhR impaired the resistant effect of OPAC against acetaldehyde. These results strongly suggested that OPAC protects the cells from the acetaldehyde-induced cytotoxicity, mainly through the AhR-dependent and Nrf2-independent enhancement of the total ALDH activity. Our findings suggest that OPAC has a protective potential in hepatocyte models and could offer a new preventive possibility of quercetin glycosides for targeting alcohol-induced chronic diseases.
Sensitivity of Tri-Axial Accelerometers within Mobile Consumer Electronic Devices: A Pilot Study

Tri-Axial accelerometers built into mobile devices allow for the measurement of motion characteristics by measuring the instantaneous acceleration of an object, compared to gravity at any given time. The objective of this study was to establish a protocol for a large scale study to determine the sensitivity of acceleration values. Five devices were used to collect instantaneous accelerations recorded by the SWAY Software in a steady state. Repeated measures were recorded in both screen-up and screen-down positions with the device laying flat and angled to 60-degrees. In the flat position, screen-up and screen-down mean accelerations were -1.0074g (+0.0202g) and 0.9966g (+0.0189g) respectively with a sensitivity of 0.0165g (+0.0086g). In the 60-degree position, screen-up and screen-down mean accelerations were -0.5094g (+0.0198g) and 0.4929g (+0.0207g) respectively with a sensitivity of 0.0190g (+0.0065g). These devices demonstrated consistent sensitivity values across multiple devices as demonstrated by low coefficients of variability.
When and why Language Assertiveness Affects Online Review Persuasion

Recent research suggests that not only what is said (i.e., opinions) but also how it is said (i.e., language styles) can affect persuasion. Extending this stream of work, the current research aims to understand how language assertiveness affects online review persuasion. Study 1 explores consumers’ general perceptions of assertive versus nonassertive language and opinions about their relative persuasiveness in online reviews. Study 2 utilizes an experimental design to examine the congruency effects between language assertiveness and temporal distance on consumer responses. We find that online reviews containing assertive (vs. nonassertive) language engender higher perceived review helpfulness and more favorable attitudes toward the reviewed business for consumers whose travel time is in the distant future, whereas nonassertive (vs. assertive) language is more effective for consumers whose travel time is in the near future. Furthermore, mediation analysis results suggest that psychological comfort is the underlying mechanism explaining such effects.
Knowledge, Beliefs, Attitude and Practices of Nurses Caring for Tobacco- Smoking Patients with Psychiatric Problems

Tobacco smoking is a common problem among residential psychiatric settings. People with mental disorders have been found to have higher rates of nicotine dependence than the general population. They also have higher mortality rate from tobacco related conditions. Nurses working in Psychiatric and mental health settings are ideally placed to deliver smoking cessation intervention to the client. Objective: Assess knowledge, beliefs, attitude and practices of nurses caring for tobacco-smoking patients with psychiatric problem. Settings: The study was conducted at two settings; Neuropsychiatry Department at Tanta University Hospital and Psychiatric Department at Psychiatric, Neurology and Neurosurgery Center at Tanta University. Tool: Psychiatric Nurses’ Knowledge, Belief, Attitude and Practices towards Patients’ Tobacco-Smoking Questionnaire was used to collect the data for the present study. Results: The present study revealed that, more than half of studied nurses have high level of knowledge and the majority of nurses have positive attitude regarding smoking cessation, and about half of nurses have low level of practice regarding smoking cessation. Also, the majority of nurses face many challenges and barriers in helping patients to stop smoking. There were positive statistically significant relationships between the nurses' knowledge, attitude and belief and their level of practice towards psychiatric patient smoking cessation. Also this study stated a positively significant relation between nurses' level of knowledge, attitude and practices with their socio demographic characteristics; age and years of experiences, attending training program, educational level and intention to help psychiatric patient in smoking cessation. Conclusion: Nurses in general have knowledge, proper beliefs and a positive attitude toward smoking cessation yet, the level of practice of smoking cessation was low. Recommendations: The main recommendations pertaining to this study is to address training needs for nurses on smoking cessation intervention methods and techniques in addition to providing mental health nurses with the skills to deliver effective Smoking cessation intervention.
The Effect of Juingong Meditation on the Theta to Alpha Ratio in the Temporoparietal and Anterior Frontal EEG Recordings

(1) Background: The effect of Juingong meditation on brainwave patterns has not been explored yet. This study aimed to study the changes in brainwave patterns produced by Juingong meditation, through electroencephalography (EEG) measurements. (2) Methods: The study included 23 participants from the Hanmaum Seon Center in Korea. EEG measurements were performed using InteraXon’s four-channel EEG measurement equipment, Muse. It measures EEG patterns in the temporoparietal and anterior frontal lobes. Brainwaves were measured in two different states: when Juingong meditation was practiced and when instructed mind wandering (IMW) was practiced. The EEG recordings were analyzed using the theta/alpha index. (3) Results: In the Juingong meditation state, the power of alpha was relatively higher than that of theta and these results were valid in the temporal parietal lobe channel. This indicates that relatively more alpha waves were induced in the temporal parietal lobe when Juingong meditation was practiced. (4) Conclusions: When Juingong meditation is practiced, the theta/alpha ratio changes without delay, which means that the practical effect of Juingong meditation on brainwave patterns is immediately apparent.
The Role of AGE-RAGE Signalling as a Modulator of Gut Permeability in Diabetes

There is increasing evidence for the role of intestinal permeability as a contributing factor in the pathogenesis of diabetes; however, the molecular mechanisms are poorly understood. Advanced glycation endproducts, of both exogenous and endogenous origin, have been shown to play a role in diabetes pathophysiology, in part by their ligation to the receptor for advanced glycation endproducts (RAGE), leading to a proinflammatory signalling cascade. RAGE signalling has been demonstrated to play a role in the development of intestinal inflammation and permeability in Crohn’s disease and ulcerative colitis. In this review, we explore the role of AGE-RAGE signalling and intestinal permeability and explore whether activation of RAGE on the intestinal epithelium may be a downstream event contributing to the pathogenesis of diabetes complications.
Pharmacological Inhibition of Epac1 Averts Ferroptosis Cell Death by Preserving Mitochondrial Integrity

Exchange proteins directly activated by cAMP (Epac) proteins are implicated in a wide range of cellular functions including oxidative stress and cell survival. Mitochondrial-dependent oxidative stress has been associated with progressive neuronal death underlying the pathology of many neurodegenerative diseases. The role of Epac modulation in neuronal cells in relation to cell survival and death, as well as its potential effect on mitochondrial function, is not well established. In immortalized hippocampal (HT-22) neuronal cells, we examined mitochondria function in the presence of various Epac pharmacological modulators in response to oxidative stress due to ferroptosis. Our study revealed that selective pharmacological modulation of Epac1 or Epac2 isoforms, exerted differential effects in erastin-induced ferroptosis conditions in HT-22 cells. Epac1 inhibition prevented cell death and loss of mitochondrial integrity induced by ferroptosis, while Epac2 inhibition had limited effects. Our data suggest Epac1 as a plausible therapeutic target for preventing ferroptosis cell death associated with neurodegenerative diseases.