Miracle-dz/UniFAR-FTUs huggingface dataset:
Interpreting Textual Artefacts: Cognitive Insights into Expert Practices

Ancient textual artefacts are the substrate of our scholarly knowledge of ancient civilisations. This knowledge is discovered, extracted, and created through the daily practice of interpretation of these ancient documents. The cognitive aspects of this act of knowledge creation are at the core of the research presented in this paper. In order to identify the various cognitive processes that are mobilised to extract meaning from ancient and difficult to read textual artefacts, I have observed how papyrologists approach the task of interpreting Roman stylus tablets and how assyriologists study tablets written in an as-yet-undeciphered script, Proto-Elamite. Linking these observations with findings from the cognitive sciences, I have identified perceptual processes that establish a visual feedback loop, a kinaesthetic feedback loop, and an aural feedback loop. These feedback loops only become effective sense-making mechanisms if they integrate processes that allow for knowledge to grow. These processes are conceptual processes that involve semantic memory, structural knowledge as well as insight, creativity and collaboration.
Association between psychosocial distress, sexual disorders, self-esteem and quality of life with male androgenetic alopecia: a population-based study with men at age 46

Objectives To study the association between androgenetic alopecia (AGA) and its severity with psychosocial well-being in male subjects aged 46 years at the population level. Design Cross-sectional study. Setting The Northern Finland Birth Cohort 1966 (NFBC1966). Participants Data were available for 892 male subjects aged 46 years. Interventions Study subjects underwent comprehensive health examinations including a skin evaluation by dermatologists and determination of AGA according to the Norwood classification. They also filled in a questionnaire battery that included previously validated questionnaires: the Hopkins Symptom Checklist-25, the Beck Depression Inventory–II; the Generalised Anxiety Disorder Screener; a 15-dimensional measure of health-related quality of life; a 12-Item General Health Questionnaire. The battery also included questions about self-esteem and sexual health. Main outcome measurements The presence of AGA and its severity, psychosocial well-being. Results AGA was found in 68.5% of subjects, 27.8% of the cases were severe, 33.2% moderate and 39.0% mild. There was no significant association between the presence of AGA or its severity with depression, anxiety, quality of life, self-esteem or sexual symptoms. Those with severe AGA reported lower sexual activity when compared with those without AGA; however, the difference was not statistically significant. Conclusions Middle-aged men with AGA did not differ from men without AGA in terms of psychosocial well-being.
Residual selectivity of some pesticides on the predatory bug, Orius minutus (Hemiptera: Anthochoridae)

ABSTRACT Orius species are predators of mites and many small insects such as aphids, scales, thrips, and insect eggs. Five insecticides (buprofezin, flonicamid, sulfoxaflor, flupyradifurone, and spirotetramat) and two acaricides (spiromesifen and emamectin benzoate) with low toxicity to natural enemies that are being used to control those pest groups were evaluated for their acute toxicity against adult females of Orius minutus (L.) (Hemiptera: Anthocoridae) and Orius laevigatus (Fieber) in a glass vial assay. Among the seven pesticides, spirotetramat and spiromesifen were the least acute toxic to both predators. In an experiment on sublethal toxicity of spirotetramat and spiromesifen against only O. minutus, we found that neither material negatively affected any of the life history parameters of O. minutus except for fecundity. A potted plant experiment was also conducted to confirm the efficacy of the combined use of spiromesifen and O. minutus against Tetranychus urticae Koch (Acari: Tetranychidae), and this combination was found to reduce the T. urticae population significantly more than the single treatment or untreated control. Therefore, we conclude that spiromesifen is a selective acaricide with less negative effect on biological parameters of O. minutus compared to other pesticides tested.
Recurrence rate of sphenoid wing meningiomas and role of peritumoural brain edema: a single center retrospective study

Objective: To evaluate the recurrence rate of the operatively treated sphenoid wing meningiomas (SWMs) in relation to other factors and role of PTBE in recurrence as a prognostic factors in a series of 67 patients. Materials and methods: The magnetic resonance imaging (MRI), and pathology data for 67 patients with SWM, who underwent surgery at Uzhhorod Regional Neurosurgical Center between 2007 and 2021 were examined. The recurrence rate and role of PTBE in recurrence in relation to: gender, age, extend of resection, histopathology, tumor volume, location and time of recurrence were evaluated. Follow-up period ranged from 6 to 168 months (median, 87 months) after surgical resection. Results: In our study, the mean age of patients is 47 years, ranged (20-74), at the average (53.5). Male 16 (23.9%), female 51 (76.1%). Mean tumor volume was (32.8cm3), ranged 4.2cm3-143.7cm3. Edema Index (EI) 1; 27 (40.3%) absent edema, and (EI) >1; in 40 (59.7%) present edema. Recurrence rate was 11 (16.4%) patients, 8 (20.0%) patients with PTBE, as compared to 3 (11.1%) patients without PTBE, (p=0,50). Female (8 patients, 15.7%), male (3 patients, 18.7%). The mean age of recurrence was 50.9 years, ranged (21-75), at the average 52.0 years. The mean age in female was 50.8 years, in male 51.0. Bivariate analysis of simultaneous effect of gender and age on SWM recurrence with logistic regression yield both main effect and interaction effect (β gender=M=7.56±6.44, P=0.24; β age=-0.034±0.031, p=0.28; β interaction term=-0.13±0.12, p=0.26). Out of 11 recurrence cases, (2 cases, 9.5%) with small tumour volume, (5 cases, 15.6%) with medium, (3 cases, 33.3%) with large, and (one case, 20.0%) with giant tumour volume. The effect of tumour volume on recurrence rate is insignificant, χ2=2.42, p=0.49. Location of SWM; the recurrence was in (6 cases, 25.0%) of CM location, (2 cases, 25.0%) of SOM and (3 cases, 11.5%) in lateral SWM, (p=0.19). Pathological grade, in the low grade (Gr.I) 7 recurrence cases (13.0%), as compared to 4cases (44.4%) in atypical Gr II, (p=0.01). Simpson grade, the recurrence rate was; 0% in Gr. I; 13.9% in Gr. II; 20.0% in Gr.III; and 33.3% in Gr. IV and 3 cases had died in the early post op (p<0.05). Conclusion: The factors which had a strong impact on the recurrence rate in our study,; i) pathological grade (Gr. II, atypical type) p=0.01 and ii) Simpson grade (extend of tumor resection, p<0.05), while, PTBE (P=0.50), tumor volume (χ2=2.42, p=0.49) and location (χ2=3.37, p=0.19), are weak and non strong factors for recurrence. However, time of recurrence is shorter in patients with PTBE (W=20.5, p=0.092). WHO Gr. II (Spearman’s p=-0.86, p=0.00063) and negligible for Simpson grade (Spearman’s=-0.15, p=0.66).
Design Concepts and Prototypes of Vibration Isolators Using Bi-Stable Foldable Structures

In this paper, a new vibration isolator using origami-based foldable structures is proposed and the performance of the isolator is numerically evaluated to prevent structural vibration. Next, the prototype of the isolator is introduced.It has been known that the origami-based foldable structures based on torsional buckling pattern provide the bistable folding motions under the given conditions. We propose to apply additional linear springs to this structure. It is numerically confirmed that the structure with additional linear springs can work as a vibration isolator around the region that the total spring stiffness of the whole structure reaches the relative minimum value that is close to zero. The prototype of the isolator consists of metallic components. The structure is adequately simplified from the above-mentioned conceptual foldable structure, still maintaining the bi-stability.Copyright © 2015 by ASME
Dynasty Control of the Process of Forming Coalition of Political Parties in the 2020 Cilegon Local Leaders Election

Abstract This paper discusses the power of political dynasties in Cilegon in the process of forming a coalition of political parties in the 2020 Pilkada. The embodiment of political dynasties continues to be accommodated to perpetuate power by putting aside the track record of organizing experience both in parties and in state institutions. The theory used in this study is the theory of political dynasties and party coalitions. The research method uses a qualitative study with an explanatory case study approach. The focus of this study is to explain how coalition maps are formed and how the influence of dynasties on political parties. The results of this study indicate that the strong influence of political dynasties in Cilegon arises because of the power that has been held since Cilegon City was founded after Banten officially became a province. At that time the elected mayor was Tubagus Aat Syafaat and continued with his sons Tubagus Iman Ariyadi and Ratu Ati Marliati until the 2020 Local Leader Election. The family mainly used the Golkar Party and lower-middle parties to perpetuate their power to form the Minimum Winning Coalition model so that passed the nomination process. Keywords: political dynasty; party coalition; pilkada; cilegon cityAbstrak Tulisan ini membahas kekuatan dinasti politik yang ada di Kota Cilegon dalam proses pembentukan koalisi partai politik di Pilkada tahun 2020. Pengejawantahan dinasti politik terus diakomodasi untuk melanggengkan kekuasaan dengan menyampingkan rekam jejak pengalaman pengorganisasian baik di partai maupun di kelembagaan negara. Teori yang digunakan dalam penelitian ini adalah teori dinasti politik dan koalisi partai. Adapun metode penelitian menggunakan kualitatif dengan pendekatan studi kasus eksplanatoris. Fokus kajian ini yaitu mengupas tentang bagaimana peta koalisi terbentuk dan bagaimana pengaruh dinasti terhadap partai-partai politik. Adapun hasil penelitian ini menunjukkan bahwa pengaruh kuat dari dinasti politik di Cilegon muncul akibat dari kekuasaan yang dimiliki sejak Kota Cilegon berdiri setelah Banten resmi menjadi Provinsi. Saat itu yang terpilih sebagai Walikota yaitu Tubagus Aat Syafaat dan dilanjut dengan anaknya Tubagus Iman Ariyadi dan Ratu Ati Marliati sampai pada saat Pilkada 2020. Keluarga tersebut memanfaatkan utamanya Partai Golkar dan partai-partai menengah-bawah untuk melanggengkan kekuasaannya untuk membentuk model Minnimal Winning Coalition agar lolos proses pencalonannya. Kata Kunci: dinasti politik; koalisi partai; pilkada; kota cilegon
Discriminated against but engaged: The role of communicative actions of racial minority employees

ABSTRACT Grounded in the situational theory of problem-solving (STOPS), two survey studies investigated how racial minority employees in the U.S. perceive and communicate about discriminatory situations within their organizations and how they are related to their engagement levels. Results of Study 1 suggested that experiences of discriminatory acts at work are negatively associated with racial minority employees’ engagement, whereas their situational perceptions are positively associated with their communicative behaviors toward direct supervisor and peers. Communicative behaviors with supervisors, not peers, in turn, fostered their engagement. Study 2 replicated and extended Study 1 in different contexts, revealing the moderating role of a diverse climate in affecting employees’ situational perceptions about workplace discrimination. Theoretical and practical implications for communication studies are discussed.
B Lineage Cells in ANCA-Associated Vasculitis

Anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) is a systemic autoimmune disease that affects small sized blood vessels and can lead to serious complications in the lungs and kidneys. The prominent presence of ANCA autoantibodies in this disease implicates B cells in its pathogenesis, as these are the precursors of the ANCA-producing plasma cells (PCs). Further evidence supporting the potential role of B lineage cells in vasculitis are the increased B cell cytokine levels and the dysregulated B cell populations in patients. Confirmation of the contribution of B cells to pathology arose from the beneficial effect of anti-CD20 therapy (i.e., rituximab) in AAV patients. These anti-CD20 antibodies deplete circulating B cells, which results in amelioration of disease. However, not all patients respond completely, and this treatment does not target PCs, which can maintain ANCA production. Hence, it is important to develop more specific therapies for AAV patients. Intracellular signalling pathways may be potential therapeutic targets as they can show (disease-specific) alterations in certain B lineage cells, including pathogenic B cells, and contribute to differentiation and survival of PCs. Preliminary data on the inhibition of certain signalling molecules downstream of receptors specific for B lineage cells show promising therapeutic effects. In this narrative review, B cell specific receptors and their downstream signalling molecules that may contribute to pathology in AAV are discussed, including the potential to therapeutically target these pathways.
Influence of religious coping and religious identity on post COVID-19 well-being among Chinese university students

ABSTRACT This research explored how religious coping and religious identity are related to post-pandemic well-being among Chinese university students. The brief RCOPE, Multi-Religion Identity Measure, and post-pandemic well-being scale were administered to 1739 university students. Results showed that religious coping was significantly positively related to post-pandemic well-being, while religious identity was significantly negatively related to post-pandemic well-being beyond demographic variables. The research implicated that university administrators and teachers can use the above inventories to understand religious coping, religious identity, and post-pandemic well-being among university students more comprehensively. Second, professional religious personnel such as Dharma Masters, Preachers, and Imams could promote students’ post-pandemic well-being by increasing their religiousness within legal places of worship. Third, the findings can help students understand the associations between religious coping, religious identity, and post-pandemic well-being, which may stimulate them to improve the latter by increasing their religious coping and religious identity. The significance and limitations of the present research are also discussed.
Curcumin as an Epigenetic Therapeutic Agent in Myelodysplastic Syndromes (MDS)

Growth Factor Independence 1 (GFI1) is a transcription factor with an important role in the regulation of development of myeloid and lymphoid cell lineages and was implicated in the development of myelodysplastic syndrome (MDS) and acute myeloid leukaemia (AML). Reduced expression of GFI1 or presence of the GFI1-36N (serine replaced with asparagine) variant leads to epigenetic changes in human and murine AML blasts and accelerated the development of leukaemia in a murine model of human MDS and AML. We and other groups previously showed that the GFI1-36N allele or reduced expression of GFI1 in human AML blasts is associated with an inferior prognosis. Using GFI1-36S, -36N -KD, NUP98-HOXD13-tg mice and curcumin (a natural histone acetyltransferase inhibitor (HATi)), we now demonstrate that expansion of GFI1-36N or –KD, NUP98-HODXD13 leukaemic cells can be delayed. Curcumin treatment significantly reduced AML progression in GFI1-36N or -KD mice and prolonged AML-free survival. Of note, curcumin treatment had no effect in GFI1-36S, NUP98-HODXD13 expressing mice. On a molecular level, curcumin treatment negatively affected open chromatin structure in the GFI1-36N or -KD haematopoietic cells but not GFI1-36S cells. Taken together, our study thus identified a therapeutic role for curcumin treatment in the treatment of AML patients (homo or heterozygous for GFI1-36N or reduced GFI1 expression) and possibly improved therapy outcome.
Markov chain and incomplete Gamma distribution analysis of weekly rainfall over Navsari region of south Gujarat

In the present study the weekly rainfall data of 34 years (1980-2013) for Navsari region were used for Markov Chain and incomplete gamma distribution analysis. The present study has been carried out to find the probabilities of occurrence of dry and wet weeks during rainy season and weekly analysis of rainfall for Navsari region. The dry and wet spell analysis was carried out for weekly rainfall based on Markov Chain Model considering less than 20.0 mm, 40.0 mm, 60.0 mm, 80.0 mm and 100.0 mm rainfall in a week as a dry week and 20.0 mm, 40.0 mm, 60.0 mm, 80.0 mm and 100.0 mm or more as a wet week. The earliest and delayed onset week of rainy season was 21 Standard Meteorological Week (SMW) (21-27 May) and 32 SMW (6-12 August), respectively. Similarly the earliest and delayed week of post-monsoon season was 40 SMW (1-7 October) and 48 SMW (26 November-2 December) during 23 29 SMW. The probability of rainfall occurrence at weekly intervals at 10, 25, 50, 75 and 90 per cent levels were assessed using the incomplete gamma distribution function. The incomplete gamma probability distribution for weekly rainfall at Navsari region indicates that there is 90% probability of getting an assured rainfall of at least 1025.6 mm and 50% probability of getting 1523.6 mm. The results through analysis have been used for agricultural planning at Navsari region. Generally, the transplanting of paddy in Navsari region is carried out during 28 to 30 standard meteorological weeks (SMW) after monsoon onset, while the sugarcane planting is done during 42 to 45 SMWs.
Comparison of Pocket Pulse Oximeter and Standard Pulse Oximeter With ABG Analysis in Critically Ill Patients

Background: Pulse oximetry (SpO2) is a standard monitoring device in patients presenting to EMDs and intensive care units (ICUs). Pocket pulse oximeters (PPOs) are used widely in wards, EMDs, and small hospitals/clinics. These inexpensive PPOs also guide therapeutic interventions. Few studies have evaluated the accuracy of SpO2 in patients presenting to critical care areas vis-à-vis devices like PPO and standard pulse oximeter (SPO). This study becomes extremely relevant in view of the ongoing crisis of the COVID-19 pandemic wherein SpO2 monitoring is very important in hospitals, quarantine centers, small clinics, or even at home. Methods: Patients presenting to critical areas who underwent arterial blood gases (ABG) analysis on the recommendation of the treating physician between November 2016 and October 2018 were included in this study. Along with the ABG analysis, a simultaneous assessment of SpO2 was done with a single PPO and SPO and all values were noted. Statistical analysis was done using the SPSS v.21. 0 for Windows. Results: The study included 300 patients. We compared the O2 saturations of ABG, SPO, and PPO with respect to sex, different age groups, and at different levels of ABG pCO2, HCO3, and pH in all patients. All parameters were compared using the Pearson’s correlation test; the results showed that ABG O2 saturations were closer to the SPO than the PPO but the differences were not statistically significant as the Pearson’s correlation values for all parameters were >0.8. We also compared the parameters by Bland Altman Plot and all observations were outside 95% CI (confidence interval), which means that there was a good agreement between O2 saturations by all three methods, that is, ABG, SPO, and PPO; however, ABG O2 saturations were closer to SPO than PPO but this difference was not statistically significant. Hence, we conclude that the PPO is a useful tool for reliable monitoring of O2 saturations. Conclusion: This study highlights that inexpensive and noninvasive PPO can be used as a standard monitoring device with reliability in critically ill patients presenting to EMDs, ICUs, and small hospitals/clinics, quarantine centers, and even at home.
Numerical Investigation of the Thermo-Acoustic Influence of the Turbine on the Combustor

Lean premixed combustion technology became state-of-the-art in modern gas turbines for power generation to reduce NOx emissions. In these systems, thermo-acoustic oscillations are easily excited in the combustion chamber. Due to the high heat release density, extreme amplitudes can occur which reduce component life or may even cause damage to the engine. Knowledge of the acoustic behavior is required in order to understand and predict these instabilities. This study of the combustor-turbine interaction is focused on the reflection coefficient analysis. The interface between the combustion system and the first turbine stage is the focus area of this study. The rotating components need to be included as outlook of this work. Compressible Large Eddy Simulation (LES) resolving acoustics is applied based on the open source CFD code OpenFOAM. Five cases of increasing complexity are presented. The main idea is to begin the study based on simple geometries such as a convergent-divergent nozzle and two nozzles respectively convergent and divergent, to proceed with increased complexity by adding a vane section, and finally to investigate the behavior of a realistic turbine design. The real engine case consists of an authentic geometry including a can annular combustion chamber and turbine vane section. These cases are studied as basic generic tests in order to validate analytical formulae and to test the CFD methods applied. Calculations with acoustic excitation and non reflecting boundary conditions (NRBC) at the computational inlet and outlet domains are carried out to verify the plausibility of the acoustic set up. The forced response approach is applied provoking a wave excitation at the inlet of the combustion chamber. Multi-harmonic excitation with small amplitudes is used to stay in the linear range. The post-processing for all cases is performed using the two-microphone method in order to calculate the reflection coefficient and the acoustic impedance taking into account the effects of the mean flow.Copyright © 2015 by Siemens Energy, Inc.