Miracle-dz/UniFAR-FTUs huggingface dataset:
Identification and exploration of gene product annotation instability and its impact on current usages

Proteins are macromolecules responsible for a wide range of activities in the structure and function of cells. Their activities have been described in different contexts as a mean to elucidate their “function”. These descriptions have been captured across biological databases in a standardized format called Gene Ontology Annotations (GOA), to disseminate the knowledge and extrapolate the information to other proteins whose function is still unknown. Furthermore, the annotations are used to analyse and interpret data from high-throughput studies and also as a benchmark for the assessment of protein function prediction algorithms. Constant changes occur in GOA that can potentially impact such usages, but only limited effort has been put into exploring their instability, or to assess the impact that these changes have on reproducibility or interpretation of previous analyses. In the present work, I performed the most comprehensive analysis of the annotation instability for 14 representative model organisms (E.coli, fruit fly, mouse, etc.). The results showed important instability patterns that were species-specific. As such information would be of use to the community to trace the instability of annotations of their interest, a web-based visualization tool was built to track these changes on a protein, functional term and species specific basis. Additionally, we identified artifacts on the annotation data that can be attributed to curation patterns. We propose such artifacts to be considered for a more accurate assessment of function prediction algorithms. Furthermore, the impact that changes in the annotations have on common settings like gene set enrichment analyses was also explored. In particular, 2,000
Joint Data-Driven Estimation of Origin–Destination Demand and Travel Latency Functions in Multiclass Transportation Networks

The traffic assignment problem is a widely used formulation for designing, analyzing, and evaluating transportation networks. The inputs to this model, besides the network topology, are the origin–destination (OD) demand matrix and travel latency cost functions. It has been observed that small perturbations to these inputs have a large impact on the solution. However, most efforts on estimating these using data do so separately and are typically based on parametric models or surveys. In this article, we present a kernel-based framework that jointly estimates the OD demand matrix and the travel latency function in single- and multiclass vehicle networks. To that end, we formulate a bilevel optimization problem, and then, we transform it to a quadratically constrained quadratic program (QCQP). To solve this QCQP, we propose a trust-region feasible direction algorithm that sequentially solves a quadratic program. In addition, we also provide an alternating optimization method. Our results show that the QCQP method achieves better estimates when compared with disjoint and sequential methods. We show the applicability of the method by performing case studies using data for the transportation networks of Eastern Massachusetts Area and New York City.
Airbnb vs booking: determinants of the use of collaborative and traditional online accommodations

ABSTRACT The collaborative economy has grown exponentially, significantly transforming certain economic sectors such as Hospitality. New collaborative platforms now compete with other digital platforms already established through hospitality services. But, are they the same types of users on both types of platforms? The objective of this study is to contribute to the sharing economy by studying consumer patterns and identifying differences between the users of sharing platforms as compared to traditional accommodation online platforms, where Airbnb and Booking are the respective world leaders. In this work, we emphasize the role of digital skills as well as trust in the digital environment, along with socio-demographic variables thought to be determinants of use of these platforms. Our results indicate that some variables including gender and income level increase the likelihood of use of Airbnb and Booking platforms in different ways. Digital skills appear to be crucial predictors of using both platforms, while greater digital trust increases the likelihood of use of Booking over that of Airbnb.
Social Support in the Workplace between Teleworkers, Office‐Based Colleagues and Supervisors

This paper draws upon the findings of qualitative interviews carried out with teleworkers, their office-based colleagues and supervisory staff of a teleworking initiative introduced by a UK public sector local authority to explore workplace social support relationships. Our study found differences between office-based and permanent teleworking staff in terms of social support. For teleworkers relationships at work are complex, with social support networks being established prior to working at home. By working from home, teleworkers were able to develop greater social support relationships with some colleagues, predominantly other teleworkers, whilst at the same time allowing them to distance themselves from negative work relationships. Overall, a social disconnection developed between teleworkers and office based staff. In contrast social support was more important for office-based workers, who valued co-worker relationships with other office-based staff.
Chelarctus and Crenarctus (Crustacea: Scyllaridae) from Coral Sea waters, with molecular identification of their larvae

Abstract Chelarctus Holthuis, 2002 is widely distributed throughout the Indo-West Pacific, but its biogeographic patterns are unknown because Southern Hemisphere areas, such as the Coral Sea, remained poorly explored. Recent cruises organized by the Muséum national d'Histoire naturelle of Paris and the Australian Institute of Marine Science allowed the molecular identification of Crenarctus crenatus (Whitelegge, 1900), Chelarctus aureus (Holthuis, 1963) and Chelarctus crosnieri Holthuis, 2002 phyllosomae. The Coral Sea C. crenatus larvae are identical to stages IX and X of Scyllarus sp. Z, described in detail by Webber and Booth (2001). Descriptions of phyllosoma stages VI, IX and X of Ch. aureus and stages IX and X of Ch. crosnieri are also presented here. Morphological differences between Crenarctus and Chelarctus larvae are established for the first time and previous misidentifications in the literature are re-assessed.
Uncovering the complexities of remote leadership and the usage of digital tools during the COVID-19 pandemic: A qualitative diary study

The COVID-19 pandemic has fundamentally changed the way people work and live. More people than ever work from home. Due to the sudden changes, leaders are faced with various challenges, such as the fear of loss of control or keeping their teams motivated. In this study, we explore the daily experiences of leaders aiming to work effectively while using digital tools and working remotely during the COVID-19 pandemic. The overarching purpose of our study is to gain a better understanding about how leaders navigate the complexities of crisis-induced remote leadership by the use of digital tools by addressing the following questions: (1) Which practices do leaders use to deal with the complexities of day-to-day remote leadership during the COVID-19 pandemic? (2) How do different digital tools fit the diverse leadership practices? (3) What drives and inhibits leaders’ effectiveness in dealing with the complexities of remote leadership during the COVID-19 pandemic? To explore these research questions, we draw on longitudinal data from 155 qualitative diaries written by 31 leaders over a five-work-day period. We identify four categories of leadership practices, namely (1) solve problems collaboratively and monitor team progress, (2) create space for socialising and teambuilding, (3) make the team feel supported and encourage feedback and (4) communicate to build a virtual culture of trust. Our findings reveal that leaders demonstrate a broad repertoire of leadership practices, whereby relation orientation is more pronounced than task orientation. Moreover, leaders tend to focus on operational and team-oriented leadership practices, and they encounter the challenge of choosing the right digital tool to match their message. Our study’s results show that they use a variety of digital tools, but video conferences seem especially suitable for supporting remote leadership practices. However, several factors have impacts on remote leadership effectiveness, which we consider in the managerial implications.
The Effect of Floor Height on Secondhand Smoke Transfer in Multiunit Housing

Secondhand smoke (SHS) exposure remains a major public health concern in the United States. Homes have become the primary source of SHS exposure, with elevated risks for residents of multiunit housing. Though this differential risk is well-documented, little is known about whether SHS exposure varies by floor height. The aim of this study was to examine whether SHS accumulates in higher floors of multiunit housing. Using validated passive nicotine sampling monitors, we sampled air nicotine concentrations on multiple floors of 21 high-rise (>15 floors) buildings in New York City. Within the buildings, measurements were collected in three locations: non-smoking individual apartments, hallways and stairwells. Measurements were collected in two winter and two summer waves to account for potential seasonality effects. We analyzed the percent of filters with detectable nicotine and quantified nicotine concentration (µg/m3). Higher floor levels were positively associated with both airborne nicotine measures, with some variation by location and season observed. In winter, the trends were statistically significant in apartments (floors ≤7: 0.022 µg/m3; floors 8–14: 0.026 µg/m3; floors ≥15: 0.029 µg/m3; p = 0.011) and stairwells (floors ≤7: 0.18 µg/m3; floors 8–14: 0.19 µg/m3; floors ≥15: 0.59 µg/m3; p = 0.006). These findings can inform interventions to mitigate the SHS exposure of residents in multiunit housing.
Testing the Permanent Income Hypothesis using the Spanish Christmas Lottery.

The Spanish Christmas Lottery is one of the most common lottery games played in Spain. This paper analyses how local windfall gains from the Christmas Lottery can affect household consumption behavior. We find that there is a significant increase in goods consumption in the winning Regions. More precisely, we find that durable goods are sensitive to lottery winnings, meaning that those households living in the winning Regions of the lottery spend more on this type of goods. Non-durable goods do not seem to react to the income shock, as the estimated effect is inelastic, although the effect is statistically significant. Despite these findings are in line with the theoretical predictions, these results imply a violation of the Permanent Income Hypothesis for long-life goods, as households do not smooth their consumption when a onetime and positive income shock occurs.
Composite Resin Preheating Techniques for Cementation of Indirect Restorations

Purpose Resin-based materials have been preheated by using different techniques and commercial devices. However, a consensus on the clinical protocol for cementing with preheated composite resins is lacking. The aim of this scoping review was to identify the different methods used for heating composite resins as used for cementing indirect adhesive restorations and to determine the benefits and limitations. Study Selection. A search was performed on PubMed/MEDLINE, Embase, Cochrane, Web of Science, Scopus, LIVIVO, and the nonpeer-reviewed literature database. Studies on preheating composite resins for cementing indirect restorations were included, with no restrictions on the type of study, year of publication, or language. The following data were extracted: preheating technique, the device used for preheating, preset temperature, and warming time. Results In total, 304 studies were identified. After removing duplicates, 270 articles were selected, and 14 articles were included in the final evaluation. Half of the included studies reported similar preheating techniques using the Calset device for composite resins. The temperatures of 54°C and 68°C were most frequently reported, with a mean warming time of 5 minutes. Conclusions Preheating composite resins for the cementation of indirect restorations reduces viscosity, but the material must be used promptly after removal from the device. Practical Implications. Different methodologies for preheating composite resins have been reported and used in clinical dental practice. To achieve good results and guide the clinician on use, the techniques for heating composite resins for cementation need to be standardized. Keeping the material warm until the restorative procedure, the thickness of the indirect restoration, and the composition of the composite resins can directly affect the outcome of the procedure.
Advances in the Management of Hodgkin’s Lymphoma

Hodgkin’s lymphoma (HL) is a malignant lymphoma of B cell origin. It is commonly seen in young adults, more so in males. The survival of patients with HL has improved dramatically over the past two decades as a result of treatment with combination chemotherapy (CT) and / or radiotherapy (RT). Though the disease has been widely reported and carefully studied in the West, limited data are available from developing countries. Earlier studies from India have shown a spectrum of HL different from that reported in western studies; the important differences include an earlier median age of onset, increased frequency of the mixed cellular (MC) histological subtype (55%-70%), presence of ‘B’symptoms and advanced disease (stage III and IV) in more than 50% of patients at diagnosis.
Mechanical Properties of Cold Mix Asphalt (CMA) Mixed with Recycled Asphalt Pavement

From the perspective of sustainability and environmental concerns, the use of cold-mix asphalt (CMA) and recycled asphalt pavement (RAP) is more advantageous than the use of hot mix asphalt (HMA) and warm mix asphalt (WMA). Some researchers used a mixture of CMA and RAP to improve the mechanical properties of pavement and made it more economical. However, only a few studies have focused on using a high content of RAP—particularly 100% RAP—as the virgin aggregate. Therefore, this study aims to analyse cold-mix asphalt (CMA) using 100% recycled asphalt pavement (RAP) instead of virgin aggregate raw materials and to determine the best mixture for the production of environmentally friendly asphalt. It is necessary to investigate the performance of CMA mixed with RAP in terms of the resilient modulus, indirect tensile strength, fatigue and rutting resistance. In this study, the percentage of bitumen emulsions added is 2%, 2.5%, 3%, 3.5%, and 4%, along with 100% RAP material. The results indicate that the fatigue life of the RAP mixture increased by 49.34% with the addition of bitumen emulsion (BE) from 2% to 4%, while the wheel tracking test experienced a decrease in rutting depth along with an increase in BE dose of 4%, which was 9 mm. The mixture containing 4% asphalt emulsion has the best performance. The results suggested that increasing the BE dosage increases the resistance against rutting and fatigue.
Hyperspectral Data Classification Algorithm considering Spatial Texture Features

As a cutting-edge technology, hyperspectral remote sensing has been widely applied in many fields, including agricultural production, mineral identification, target detection, disaster warning, military reconnaissance, and urban planning. The collected hyperspectral data have high spectral resolution and spatial resolution and are characterized by a large amount of information, redundancy, and high dimension. At the same time, there is a strong correlation between the bands. Therefore, hyperspectral data not only provides rich information but also brings great challenges for subsequent processing. Hyperspectral image classification is a hot issue in remote sensing information processing. Traditional hyperspectral remote sensing image classification methods only use the spectral features of the image without considering the spatial features of each pixel in the hyperspectral remote sensing image. In this paper, a hyperspectral image classification method is proposed not only considering spectral features but also considering texture features. This method jointly considers both these features. Firstly, six texture features contributing a lot to each pixel of hyperspectral remote sensing image are extracted by using a gray level cooccurrence matrix, and then, the spectral features of each pixel in neighbor are combined to form the texture-spectral features. Finally, the classification experiment of the Indian Pines and Pavia University scene is carried out based on a support vector machine and extreme random tree algorithm, and the obtained results show that the proposed method achieves higher classification performance than the traditional method.
Is decision-making impairment an endophenotype of Anorexia Nervosa?

Introduction Patients with anorexia nervosa (AN) show impaired decision-making ability, but it is still unclear if this is a trait marker, i.e. a stable endophenotype of AN, or a state parameter, i.e. being explained by present symptoms and associated comorbidity. Objectives We aimed to determine whether decision-making impairment is an endophenotype of AN. We hypothesized that decision-making alteration would not respect the criteria of an endophenotype, and that these alterations would have a relationship with illness severity. Methods Ninety-one patients with acute AN (A-AN), 90 unaffected relatives (UR), 23 patients remitted from AN (R-AN) and 204 healthy controls (HC) underwent the Iowa Gambling Task (IGT) and psychometric assessments. Prospective Valence Learning model (PVL) was employed to distinguish the cognitive dimensions underlying the decision-making process. Performance at the IGT was compared between the four groups and then analysed according to clinical and psychometric variables. Results Patients with A-AN scored worse than UR and HC at the IGT (p<.01). PVL-feedback sensitivity parameter was lower in patients with R-AN and A-AN than in the two other groups (p<.01) and PVL-loss aversion parameter was lower in A-AN than in UR and R-AN (p<.01). Decision-making style, in particular learning and loss aversion parameters, accounted for a significant part of variance of psychopathology in patients with AN (p<.01). Conclusions Impaired decision-making represents a state-associated, cognitive hallmark of AN. The aggravation of reward modulation along with illness progression may explain the persistence of symptoms despite their consequences on health. Reversal of decision-making impairment should not be limited by inherited vulnerability. Disclosure No significant relationships.
How do top executives handle their work and family life? A taxonomy of top executives' work–family balance

Aiming to increase understanding of work–family balance at the executive level and to derive implications for human resource management, this study analyses patterns of the way in which different top executives handle the interface between work and family domains. Drawing on role theory, research on work–family linkages and a qualitative study with 42 top executives, the authors identify eight constructs that constitute top executives' work–family balance. By applying cluster analysis to dyadic data from 220 top executives and their life partners, they detect five top executive work–family balance types, according to the interplay of the top executives' satisfaction and functioning at work and at home, as well as the conflicts between the two life domains. The balance types imply significant variance in highly relevant outcomes, such as job performance and job attitudes.
Transient Precipitation Increase During Winter in the Eastern North America

Previous studies have reported that enhanced eddy moisture convergence causes future increase of winter precipitation in the eastern North America in a warmer climate. This study investigates the mechanisms of the change in moisture convergence. Using ensemble simulations from climate models and composite analysis of moisture budget, we show that in the southeast United States, two thirds of the enhanced moisture convergence is caused by local thermodynamics due to increase of moisture, while one third is caused by stronger eddy wind convergence. In the north, it is primarily caused by the increase of moisture gradient associated with the spatial distribution of both the climatological temperature and the large amplitudes of the eddy temperature in the region of the storm tracks. Results help to better understand the physical mechanism of more winter precipitation in the eastern North America in a warmer climate.
Agent-based simulation of mobility in real-world transportation networks: effects of acquiring information and replanning en-route (Extended Abstract)

Macroscopic and equilibrium-based models for traffic assignment and simulation disregard many details of traffic movement. For some applications, one needs to understand and analyze microscopic properties. This paper discusses an agent-based simulation of route choice under different conditions of demand generation, number, and types of travelers. The effects of en-route decision-making and vehicle-tovehicle communication were tested in a real-world scenario. The analysis has considered different classes of travelers, which is only possible if a microscopic, agent-based simulation is used. The main conclusion is that for travelers whose trips are long, there is a benefit of using communication and replan en-route, depending on the demand volume.
Critical Reading Skills of the Descriptive Genre Through E-Learning

It has been found that in reading lectures, students at Bung Hatta University had difficulty understanding the text because they did not know about the genre of the text. This is because students study theory more than they practice reading. The purpose of this research was to describe the critical reading ability of Indonesian Language Education (Pindo) FKIP students at Bung Hatta University by applying the descriptive text genre. Theories proposed by Akaaya, Haromi and Akin were employed. Qualitative and quantitative methods were used. The research subjects were 23 students of the Indonesian Language and Literature Education Study Program, FKIP Bung Hatta University, Padang, class of 2020/2021. The score obtained for making and answering questions was 8.65, determining the structure of descriptive texts was 8.52, determining the structure of exposition texts was 8.60, concluding news texts was 7.78, and commenting on news texts was 7.91. The results showed that overall, the students of Pindo FKIP Bung Hatta University were able to read critically with a score of 8.25, which can be categorized as good. Keywords: descriptive text genre, critical reading, e-learning
High Step-Down Bridgeless Sepic/Cuk PFC Rectifiers With Improved Efficiency and Reduced Current Stress

In this article, two high step-down bridgeless power factor correction rectifiers based on the switched inductor network (SIN) are introduced. The proposed rectifiers employ the SIN to provide high step-down voltage gain with a higher duty cycle than the competitors. They also offer higher efficiency, lower current stress, and total peak switching device powers. A thorough and straightforward design algorithm in the discontinuous conduction mode is provided that ensures a unity power factor and a low total harmonic distortion with a simple control scheme. As a demonstration of the superior performance of the proposed rectifiers, a 300-W high-gain sepic rectifier setup with 48Vdc output voltage from a 230Vrms/50Hz source is built in the laboratory.