Miracle-dz/UniFAR-FTUs huggingface dataset:
Effects of Isothermic Irrigation on Core Body Temperature During Endoscopic Urethral Stone Treatment Surgery Under Spinal Anesthesia: A Randomized Controlled Trial.

Purpose? Isothermic irrigation decreases the reduction in core temperature and shivering in patients undergoing transurethral resection of prostate gland but this effect has not been studied in patients undergoing endoscopic urethral stone treatment surgery. The current study is designed to study the effect of isothermic hydration on core temperature in patients scheduled for endoscopic urethral stone treatment surgery under spinal anesthesia. Materials and Methods? Sixty patients allocated randomly into two groups. In GroupW (n = 30) irrigation fluid at 37°C was used whereas at room temperature in GroupRT (n = 30). Spinal anesthesia was performed at L3-L4 interspace with 15mg of hyperbaric bupivacaine. Core temperature, shivering, and hemodynamic parameters were measured every minute until 10th minute and five minute intervals until the end of operation. Shivering and surgeon comfort was also recorded. The primary outcome was the core temperature at the end of surgery. Frequencies, means, standard deviations, percentages, chi-square tests, independent samples t-test, and Mann Whitney U tests were used where eligible for the statistical analysis.Results? Baseline core temperature was 36.6 ± 0.4°C in GroupW and 36.6 ± 0.5°C in GroupRT (P = .097) which decreased to 36.0 ± 0.5°C and 35.2 ± 0.7°C respectively (P = .018) at the end of operation. Shivering was observed in 36.7% (n = 11) in GroupRT and 6.7% (n = 2) in GroupW (P = .012). Hemodynamic parameter changes and demographic data were not significant between groups.Conclusion? Isothermic irrigation decreases both the reduction in core temperature and the incidence of shivering while increasing the surgeon comfort.
A Study on the influence of Emotional Intelligence on Employee Performance

The present paper is an attempt to study the relationship between emotional intelligence and employee performance in the organisational context. The concepts of emotional intelligence, its dimensions, employee performance and its components have been presented in the first part of the discussion. Emotional intelligence is a skill in which persons will differ significantly due to a number of factors. The factors that influence the emotional intelligence are demographic factors, personal factors, educational factors and work life factors. Emotional intelligence has a role in the utilisation of skill and knowledge of an employee for achieving the organisational objectives. Emotional Intelligence is constituted by its four dimensions such as Emotion Perceiving, Emotion Using, Emotion Understanding and Emotion Managing. Employee performance is the effort put by the employees for the accomplishment of organisational objectives. Employee performance is the result of employee behaviour at the work place with the interaction of three factors such as Emotional intelligence, Cognitive Intelligence and Work Environment. The outcomes of employee behaviour are Job performance, Interpersonal facilitation and work attitude. The consolidated result of these components contributed by an employee at the work place is termed as employee performance. We have also presented a conceptual model describing the influence of emotional intelligence on the employee performance.
Towards (comparative) educational research for a finite future

ABSTRACT Educational scholars, particularly those working in comparative education, have largely failed to recognise, let alone discuss, the impending finite-ness of global resources. The field continues to operate on an assumption of infinite resources, an implicit cultural horizon in place since at least the Western Enlightenment. It has missed the epochal shift that is now upon us; unable to contribute to the deep transformation of research and practices that has now become urgent. Herein we discuss how such concerns might be addressed, suggesting an approach that centres ontological alterity through comparative method as means of making the turn towards a sustainable future.
Short-term blood pressure variability outweighs average 24-h blood pressure in the prediction of cardiovascular events in hypertension of the young.

OBJECTIVE The association of short-term blood pressure (BP) variability (BPV) with cardiovascular events (CVEs) is controversial. Aim of this study was to investigate whether BPV measured as weighted 24-h SD was associated with CVE in a prospective cohort study of young patients screened for stage 1 hypertension. METHODS We performed 24-h ambulatory BP monitoring in 1206 participants aged 33.1 ± 8.5 years, untreated at baseline examination. Participants were divided into two categories with low (<12.8 mmHg) or high (≥12.8 mmHg) SBPV. Hazard ratios for CVE associated with BPV expressed either as continuous or categorical variable were computed from multivariable Cox models. RESULTS During 15.4 ± 7.4 years of follow-up there were 69 fatal and nonfatal CVE. In multivariable Cox models, high SBPV was an independent predictors of CVE [2.75 (1.65-4.58); P = 0.0001] and of coronary events [3.84 (2.01-7.35), P < 0.0001]. Inclusion in the model of development of hypertension requiring treatment during the follow-up, did not reduce the strength of the associations. Addition of SBPV to fully adjusted models had significant impact on risk reclassification and integrated discrimination (relative integrated discrimination improvement for BPV as continuous variable: 13.5%, P = 0.045, and for BPV as categorical variable: 26.6%, P = 0.001). When the coefficient of variation was used as BPV metric similar results were obtained. Of note, in all Cox models average 24-h BP was no longer an independent predictor of outcome after BPV was included. CONCLUSION Short-term BPV adds to the risk stratification for cardiovascular events in young-to-middle-age patients screened for stage 1 hypertension over and above traditional 24-h ambulatory monitoring indexes.
Dipeptidyl Peptidase 4 Activity Is Related to Body Composition, Measures of Adiposity, and Insulin Resistance in Subjects with Excessive Adiposity and Different Degrees of Glucose Tolerance

Background The enzyme dipeptidyl peptidase 4 (DPP4) has been recently recognized as an adipo-myokine. However, studies that associate its constitutive activity with body composition, anthropometry, and insulin resistance (IR) are very scarce and included only healthy people. Methods First, we investigated the relationships of constitutive DPP4 activity, body composition (assessed by bioelectrical impedance analysis), and measures of adiposity and IR in fifty-two subjects of both sexes, 18-50 years, and BMI ≥25.0 kg/m2 who comprised three groups according to glucose tolerance. Additionally, we evaluated associations among DPP4 activity and adipokines, gut peptides, and biochemical variables at fasting and 30 and 60 min after a standardized meal intake. Results DPP4 activity was no different among the three groups. At fasting, pooled analysis showed it was positively correlated with measures of central adiposity, such as WC (P = 0.011) and WHR (P = 0.009), and with all measures of IR, but inversely related to indexes of general adiposity, such as fat mass percentage (P = 0.014) and BAI (P = 0.0003). DPP4 activity was also associated with lean mass (r = 0.57, P < 0.0001). After meal intake, DPP4 activity remained significantly associated with insulin, leptin, and resistin. In multiple regression analysis, BAI, WHR, percent lean mass, HOMA-IR, and leptin influenced DPP4 activity and explained approximately 26% of the variance on it. Conclusions Constitutive DPP4 activity is positively associated with lean mass, central adiposity, and IR and negatively to general adiposity. Furthermore, it seems to be influenced by body composition and IR and could also be viewed as an adipo-myokine in subjects with excessive adiposity and different stages of glucose tolerance.
Recognizing two new Hippolyte species (Decapoda, Caridea, Hippolytidae) from the South China Sea based on integrative taxonomy

Hippolyte shrimps exhibit abundant biological diversity and display great ecological significance in seaweed bed ecosystems. Dozens of Hippolyte specimens were collected from Hainan Island and the Xisha Islands in the South China Sea. Detailed examination indicates that some of these specimens represent new Hippolyte species. Based on morphological, genetic, and ecological data, Hippolyte chacei sp. nov. and H. nanhaiensis sp. nov. are described. H. chacei sp. nov. was collected from the Sargassum sp. biotope in Hainan Island and is distinguished from congeners by its unique mandible and the dactylus of the third to fifth pereiopods; this species has a basal position in the Indo-West Pacific species clade in the phylogenetic tree which is reconstructed based on 16S rRNA gene. H. nanhaiensis sp. nov. was collected from the biotopes of Galaxaura sp. or Halimeda sp. in the Xisha Islands, and it differs from congeners in a series of characters associated with rostrum, scaphocerite, antennular peduncle, and spines on the dactylus of the third to fifth pereiopods. Additionally, it is sister to H. australiensis in the phylogenetic tree. A key to identifying mature female Hippolyte species of the Indo-West Pacific and neighboring seas is provided.
The Missing Ingredient in Zero-Shot Neural Machine Translation

Multilingual Neural Machine Translation (NMT) models are capable of translating between multiple source and target languages. Despite various approaches to train such models, they have difficulty with zero-shot translation: translating between language pairs that were not together seen during training. In this paper we first diagnose why state-of-the-art multilingual NMT models that rely purely on parameter sharing, fail to generalize to unseen language pairs. We then propose auxiliary losses on the NMT encoder that impose representational invariance across languages. Our simple approach vastly improves zero-shot translation quality without regressing on supervised directions. For the first time, on WMT14 English-FrenchGerman, we achieve zero-shot performance that is on par with pivoting. We also demonstrate the easy scalability of our approach to multiple languages on the IWSLT 2017 shared task.
Contrasting effects of different pH‐raising materials on N2O emissions in acidic upland soils

Acidic soils, occupying ca. 40% of the world's arable soils, often need to be managed (e.g., to raise their pH and to improve crop productivity); however, the environmental impact of raising soil pH is often difficult to assess. Increasing soil pH stimulates the reduction of N2O to N2, thus lowering N2O emissions associated with denitrification, but can also increase autotrophic nitrification rates and related N2O emission. Using a 15N tracing technique, we provide process‐based insights into the effects of two acid‐neutralizing materials (quicklime [CaO] vs. pig manure) on N2O emissions in an acidified upland soil that had experienced excessive N application. Without pH adjustments we found that N2O emissions, stimulated by supply of reactive N, were related to denitrification‐ and heterotrophic nitrification‐derived N2O emissions, whereas autotrophic nitrification‐derived N2O emissions declined with decreasing soil pH. These effects were reversed by increasing soil pH via liming. However, increasing the soil pH via application of pig manure significantly increased soil N2O emissions from both nitrification and denitrification. Our study highlights that pH‐amelioration practices may enhance N2O emissions depending on the type of material applied to the soil. Therefore, both pH remediation and greenhouse gas mitigation options need to be considered together to avoid adverse environmental effects. The effect of different acid‐neutralizing materials on soil N2O emissions should be incorporated into ecosystem models to better estimate global N2O emissions when pH amelioration is practised.
Real-Time Monitoring of Ascorbic Acid-Mediated Reduction of Cytotoxic Effects of Analgesics and NSAIDs on Tenocytes Proliferation

Tendinopathy is a common painful musculoskeletal disorder treated by injection of analgesics and nonsteroidal anti-inflammatory drugs (NSAIDs), which are believed to have cytotoxicity toward tenocytes. Ascorbic acid is an antioxidant that promotes collagen biosynthesis and prevents free radical formation. It is believed to protect tenocytes from oxidative stress. The optimal concentration of ascorbic acid, especially when used in conjunction with anesthetics and NSAIDs injection, to treat different stages of tendinopathies is unknown. Human tenocytes were isolated from a torn edge of the supraspinatus tendon of a 51-year-old male patient during arthroscopic repair. We monitored real-time changes in human tenocyte proliferation upon exposure to different concentrations of ascorbic acid, bupivacaine, and ketorolac tromethamine using the xCELLigence system. No significant changes in cell index were observed between the control group and tenocytes treated with the 3 concentrations of ascorbic acid. Tenocytes exposed to 0.5% bupivacaine and 30 or 15 mg/mL ketorolac tromethamine revealed significant reduction in tenocytes proliferation. Bupivacaine 0.5% with 250 μg/mL ascorbic acid and 15 mg/mL ketorolac tromethamine with 250 μg/mL ascorbic acid showed the least cytotoxicity against tenocytes. The optimal ascorbic acid concentration required to reduce the cytotoxic effects of bupivacaine and ketorolac tromethamine was demonstrated using this platform.
Algılanan Müdür Yönetim Tarzı ve İçsel Motivasyonun Öğretmenlerin Örgütsel Bağlılığına Etkisi

Bu calismanin amaci, ogretmen algilarina gore algilanan mudur yonetim tarzi ve icsel motivasyonun orgutsel baglilik ile iliskisini betimlemektir. Bu amacla calismaya katilan ogretmenlerin algilanan mudur yonetim tarzi, icsel motivasyon ve orgutsel baglilik duzeyi betimlenerek, degiskenler asindaki iliskiler arastirilmistir. Arastirmanin calisma grubunu 2018-2019 egitim ogretim yili Edirne ili Uzunkopru ilce merkezinde yer alan toplam 26 resmi ilk ve orta dereceli okullarda gorevli 480 ogretmen olusturmustur. Analizler 391 veri seti uzerinden yapilmistir. Birinci bolumunde calismaya katilan ogretmenlerin kisisel bilgilerinin yer aldigi veri toplama aracinin ikinci bolumde Ustuner (2016) tarafindan gelistirilen “Algilanan Mudur Yonetim Tarzi Olcegi”, Dundar, Ozutku ve Taspinar (2007) tarafindan gelistirilen “Icsel Motivasyon Olcegi” ve Ustuner (2009) tarafindan gelistirilen “Ogretmenler icin Orgutsel Baglilik Olcegi” yer almistir. Verilerin analizinde SPSS 18 paket programi kullanilmistir. Arastirmada betimsel istatistik analizleri, t testi, tek yonlu varyans analizi ve regresyon analizi yapilmistir. Elde edilen bulgulara gore, ogretmenlerin isbirlikli mudur yonetim tarzi algi duzeyinin oldukca yuksek, otoriter mudur yonetim tarzi algi duzeyinin dusuk, ilgisiz ve karsi koyucu mudur yonetim tarzlari algi duzeyinin ise oldukca dusuk duzeyde, icsel motivasyon algi duzeyinin oldukca yuksek ve orgutsel baglilik algi duzeyinin yuksek duzeyde oldugu gorulmustur. Arastirmada ayrica cinsiyet ve brans degiskenine gore anlamli farklilik oldugu, kidem degiskenine gore anlamli farklilik olmadigi bulgusuna ulasilmistir. Arastirmada algilanan isbirlikli mudur yonetim tarzi ve icsel motivasyonu ile ogretmenlerin orgutsel bagliligi arasinda pozitif ve orta duzeyde anlamli bir iliski bulunmus ve ogretmenlerin algilanan isbirlikli, otoriter, ilgisiz, karsi koyucu mudur yonetim tarzlari ile icsel motivasyonun onlarin orgutsel bagliliginin anlamli bir yordayicisi oldugu belirlenmistir.
Abordagem molecular da leucemia transitória e da leucemia mieloide, associadas à síndrome de down

vii INTRODUCAO 1 1. Hematopoiese normal e leucemica 1 2. Leucemogenese na sindrome de Down 3 3. Gene GATA1 4 3.1. Familia GATA 5 3.2. Mutacoes no GATA1 da LT e LM-SD 6 4. Mutacoes no gene GATA1 em pacientes com anemia diseritropoietica 11 4.1. Estudos experimentais de gata1 em camundongos 13 4.2. Interacao proteina-proteina 15 5. Outras mutacoes associadas a LT e LM-SD 16 6. Trissomia do cromossomo 21 e suas implicacoes 18 6.1. Efeitos da trissomia do cromossomo 21 na hematopoiese fetal 19 6.2. Expressao genica da trissomia do cromossomo 21 20 6.3. Oncogenes candidatos leucemicos do cromossomo 21 20 6.4. miRNAs codificados pelo cromossomo 21 22 7. Doenca residual minima (DRM) 24 8. Metodos de diagnostico para LT e LM-SD 25 OBJETIVOS 28 CASUISTICA E METODOS 29 1. Pacientes 29 1.1. Pacientes com suspeita clinica de anemia diseritropoietica sem SD 30 2. Analise citogenetica 30 2.1. Obtencao de metafases a partir do cultivo de leucocitos de sangue periferico (SP) e de celulas de medula ossea (MO) 30 3. Analise Molecular 32 3.1. Extracao de DNA a partir de linfocitos 33
Expression analysis of tumour necrosis factor alpha (TNF-α) and alkaline phosphatase in occupational workers exposed to low dose of X-radiation: A case-control study.

Objectives To evaluate liver and inflammatory biomarkers in occupationally exposed radiology workers. METHODS The descriptive study was conducted at Mufti Mehmood Memorial Teaching Hospital and Gomal Centre of Biochemistry and Biotechnology, Gomal University, Dera Ismail Khan, Pakistan, from September 2017 to May 2018, and comprised X-ray technicians working 48-72 hours per week, and a group of age- and gender-matched unexposed healthy controls. The exposed group was divided into three sub-groups based on their radiation work duration. Liver health status involved estimation of alanine aminotransferase, aspartate aminotransferase, alkaline phosphatase, gamma-glutamyl transferase GGT and bilirubin through automated chemistry analyser, while serum tumour necrosis factor-alpha and interleukin- 6 levels through enzyme-linked immunosorbent assay technique. Relative gene expression analysis of tumour necrosis factor-alpha and alkaline phosphatase was performed through reverse transcription-polymerase chain reaction. Data was analysed using SPSS 20. RESULTS Of the 70 subjects, 50(71.4%) were cases with a mean age of 36.98±8.07 years and 20(28.6%) were controls with a mean age of 36.80±7.78 years. Serum alanine aminotransferase and alkaline phosphatase levels showed significant elevation in the cases compared to the controls (p<0.0001), although alanine aminotransferase levels were within the normal range. The difference in aspartate aminotransferase, gamma-glutamyl transferase and bilirubin levels was not significant (p>0.05). Tumour necrosis factor-alpha concentration was significantly high in the cases compared to the controls (p<0.0001). In contrast with proteomic analysis, relative gene expression analysis revealed reduced level of alkaline phosphatase and tumour necrosis factor-alpha in the cases compared to the controls (p<0.05). CONCLUSIONS Serum proteomic analysis of X-ray technicians indicated acute inflammatory conditions, while genomic analysis exhibited down-regulation of alkaline phosphatase and tumour necrosis factor-alpha genes.
Wuchsstoff und Wachstum

Die wichtigsten Ergebnisse der vorliegenden Arbeit konnen folgenderweise zusammengefasst werden. Die stetige Bildung (12) eines physikalisch zu handhabenden wachstumsfordernden Stoffes (Wuchsstoff) in der aussersten Spitze einer Avena-Koleoptile wird bewiesen (1), (5), (6), (20). Eine Methode zur quantitativen Analyse dieses Stoffes ist ausgearbeitet worden (1), (4), (9), (10), (11), (12), (13) und hat es moglich gemacht folgende Eigenschaften desselben zu bestimmen. Innerhalb gewisser Grenzen beschrankt der Wuchsstoff das Wachstum vollig (9) und ist das Wachstum der Wuchsstoffmenge proportional (9), (13); ohne Wuchsstoff kein Wachstum (38), (42). *) Der Wuchsstoff ist licht- (36) und hitzebestandig (37), hat ein Molekulargewicht zwischen 350 und 400 (29), und wird beim Wachstum aufgebraucht (32), (40). Wahrschein- lieh ist er nicht spezifisch (48) und bewirkt nur eine erhohte Dehnbarkeit der Zellwand (49). In der Koleoptile ist der Wuchsstoffstrom polar (31), (33), die Konzentration des Stoffes nimmt basalwarts ab (41). Ein anderer Faktor, Zellstreckungsmaterial genannt, beschrankt das vom Wuchsstoff hervorgerufene Wachstum (14), (15), (43), (45); in der Koleoptile nimmt seine Konzentration basal warts zu (46). Wuchsstoff und Zellstreckungsmaterial sind die einzig nachweisbaren inneren „limiting factors” des Wachstums (14), (15), (39), mittels diesen beiden ist das normale Wachstum einer Koleoptile vollig erklarlich (47), (47a). Die nicht mehr wachsenden basalen Koleoptilzonen haben ihr Wachstum nur durch Wuchsstoffmangel eingestellt (42). Das Wachstum des Mesokotyls wird ebenfalls vom Wuchsstoff bedingt (44). Eine geringe Lichtmenge (1000 M.K.S.) ruft sofort eine kurz anhaltende Verringerung der aus der Spitze hinausdiffundierenden Wuchsstoffmenge hervor (52), welche die Lichtwachstumsreaktion veranlasst (53). Einseitig einfallendes Licht lenkt den sonst allseitig aus der Spitze kommenden Wuchsstoffstrom derweise ab, dass die Lichtflanke sehr wenig (58) und die Schattenflanke einen Uberschuss des Wuchsstoffes empfangt (56), (59), (60), welche Wuchsstoffdifferenz vollstandig genugt um die phototropischen Krummungen zu erklaren; es gibt also keine phototropischen Reizstoffe (51), (61). Als Folge der erhaltenen Resultate muss die Theorie von Blaauw fur die Erklarung der phototropischen Krummung nach Spitzenreizung abgelehnt werden (54); der Lichtabfall ist fur die Entstehung der letzteren bestimmend. Am Schluss dieser Arbeit, die ganz im Botanischen Institut der Utrechter Universitat bearbeitet wurde, muss ich meinem Lehrer und Vater Herrn Prof. Dr. F. A. F. C. Went meinen besonderen Dank aussprechen fur so manche Anweisung und namentlich fur seine ausserst scharfe Kritik, mittels welcher er meine Arbeit stetig gefordert hat. Herrn Prof. Dr. L. G. M Baas-Becking danke ich fur vielerlei Anregung, und schliesslich bin ich Herrn Assistenten H. E. Dolk sehr verplichtet fur alle Hilfe und die Uberlassung einiger sehr wichtigen Versuchsresultate.
Economic Attitudes, Social Attitudes and Their Psychological Underpinnings – A Study of the Finnish Political Elite

We investigated the relation between economic and social attitudes and the psychological underpinnings of these attitudes in candidates (N = 9515) in the Finnish 2017 municipal elections. In this politically elite sample, right-wing economic attitudes and social conservatism were positively correlated (r = 0.41), and this correlation was predominantly driven by those on the economic left being socially liberal, and vice versa. In terms of underlying psychological processes, consistent with dual process models of political ideology, the anti-egalitarian aspect of social dominance orientation was more strongly associated with right-wing economic attitudes, and the conventionalism and aggression aspects of right-wing authoritarianism with social conservatism. Our results show that even in a non-United States context in which the masses organize their political attitudes on two independent dimensions, these dimensions are moderately aligned among certain parts of the political elite, and that the political attitudes of the political elite can be traced to underlying psychological motivations. We argue that equality concerns could play a role in explaining why the left-right and liberal-conservative dimensions are more strongly aligned among those on the left and those more liberal.