Miracle-dz/UniFAR-FTUs huggingface dataset:
Influence of incubating monocalcium phosphate with liquid hog manure on inorganic phosphorus, organic phosphorus and phosphorus availability in two Quebec soils

The effects of incubating monocalcium phosphate monohydrate (MCPM) with liquid hog manure (LHM) on P availability and uptake by Italian ryegrass (Lolium multiflorum Lam.) were evaluated in a 99-d growth chamber experiment. Liquid hog manure with (0.738 g P kg−1 fresh LHM) or without MCPM was aerated for a 21-d period at 24 °C. The soils used in this experiment were an Ormstown silty clay loam (Orthic Humic Podzol), and a Ste. Rosalie clay loam (Humic Podzol). Five treatments were applied to each soil: (i) control with no LHM or MCPM additions, (ii) MCPM, (iii) LHM incubated without MCPM, (iv) LHM incubated with MCPM, and (v) the separate applications of MCPM and LHM incubated without MCPM. Rates of MCPM and LHM applications were 513 kg P2O5 ha−1 and 32 t ha−1, respectively. Incubating LHM with MCPM resulted in a loss of 6% of the total manure-N during the 3-wk incubation period, compared with a 67% loss from the unamended LHM. Additions of both MCPM and LHM had the same effect on shoot-P contents and soil.
Single Junctions in ZnO Varistors Studied by Current-Voltage Characteristics and Deep Level Transient Spectroscopy

The electronic properties of individual grain boundaries in ZnO varistors were characterized by current-voltage ( I-V ) measurements and high-temperature zero-bias deep level transient spectroscopy (DLTS). A single-junction electrode pattern was designed using photolithography in order to study these properties. It was found that interface trap energy levels and capture cross sections vary with the polarities of trap filling pulses. The behavior indicates that the grain boundary potential barriers are not symmetric. Asymmetry was also observed in I-V measurements. Intergranular differences in chemical composition, distribution of chemisorbed oxygen, and grain boundary microstructure were suggested to be responsible for the asymmetry in electronic properties.
Discriminating Microbial Community Structure Between Peri-Implantitis and Periodontitis With Integrated Metagenomic, Metatranscriptomic, and Network Analysis

Peri-implantitis and periodontitis are both polymicrobial diseases induced by subgingival plaque accumulation, with some differing clinical features. Studies on the microbial and gene transcription activity of peri-implantitis microbiota are limited. This study aimed to verify the hypothesis that disease-specific microbial and gene transcription activity lead to disease-specific clinical features, using an integrated metagenomic, metatranscriptomic, and network analysis. Metagenomic data in peri-implantitis and periodontitis were obtained from the same 21 subjects and metatranscriptomic data from 12 subjects were obtained from a database. The microbial co-occurrence network based on metagenomic analysis had more diverse species taxa and correlations than the network based on the metatranscriptomic analysis. Solobacterium moorei and Prevotella denticola had high activity and were core species taxa specific to peri-implantitis in the co-occurrence network. Moreover, the activity of plasmin receptor/glyceraldehyde-3-phosphate dehydrogenase genes was higher in peri-implantitis. These activity differences may increase complexity in the peri-implantitis microbiome and distinguish clinical symptoms of the two diseases. These findings should help in exploring a novel biomarker that assist in the diagnosis and preventive treatment design of peri-implantitis.
Reaction Kinetics of One-Pot Xylan Conversion to Xylitol via Precious Metal Catalyst

The hydrolytic hydrogenation of xylan to xylitol by a one-pot process was studied in detail in a batch reactor. The reaction was catalyzed by a combination of diluted sulfuric acid and precious metal Ru on carbon powder. Process parameters were varied between 120–150°C, while maintaining constant hydrogen pressure at 20 bar and an acid concentration equivalent to pH 2. The xylan solution consisted of 1 wt% beechwood powder (Carl Roth, >90%) in deionized water. Sulfuric acid was added to the solution until pH two was reached, then the 0.3 wt% catalyst powder (5% Ru on Act. C) was added and the solution was put into the batch reactor. The first approach of kinetic modeling began with conventional first-order kinetics and compared this to a more complex model based on Langmuir–Hinshelwood kinetics. The xylan and xylitol data reached a good fit. However, the modeling results also showed that the rate-limiting step of xylose-formation was still not represented in a satisfactory manner. Therefore, the model was adapted and developed further. The advanced model finally showed a good fit with the intermediate product xylose and the target product xylitol. The overall modeling methods and results are presented and discussed.
Tolerance to Bone Marrow Transplantation: Do Mesenchymal Stromal Cells Still Have a Future for Acute or Chronic GvHD?

Mesenchymal Stromal Cells (MSCs) are fibroblast-like cells of mesodermal origin present in many tissues and which have the potential to differentiate to osteoblasts, adipocytes and chondroblasts. They also have a clear immunosuppressive and tissue regeneration potential. Indeed, the initial classification of MSCs as pluripotent stem cells, has turned into their identification as stromal progenitors. Due to the relatively simple procedures available to expand in vitro large numbers of GMP grade MSCs from a variety of different tissues, many clinical trials have tested their therapeutic potential in vivo. One pathological condition where MSCs have been quite extensively tested is steroid resistant (SR) graft versus host disease (GvHD), a devastating condition that may occur in acute or chronic form following allogeneic hematopoietic stem cell transplantation. The clinical and experimental results obtained have outlined a possible efficacy of MSCs, but unfortunately statistical significance in clinical studies has only rarely been reached and effects have been relatively limited in most cases. Nonetheless, the extremely complex pathogenetic mechanisms at the basis of GvHD, the fact that studies have been conducted often in patients who had been previously treated with multiple lines of therapy, the variable MSC doses and schedules administered in different trials, the lack of validated potency assays and clear biomarkers, the difference in MSC sources and production methods may have been major factors for this lack of clear efficacy in vivo. The heterogeneity of MSCs and their different stromal differentiation potential and biological activity may be better understood through more refined single cell sequencing and proteomic studies, where either an “anti-inflammatory” or a more “immunosuppressive” profile can be identified. We summarize the pathogenic mechanisms of acute and chronic GvHD and the role for MSCs. We suggest that systematic controlled clinical trials still need to be conducted in the most promising clinical settings, using better characterized cells and measuring efficacy with specific biomarkers, before strong conclusions can be drawn about the therapeutic potential of these cells in this context. The same analysis should be applied to other inflammatory, immune or degenerative diseases where MSCs may have a therapeutic potential.
Ordered nitrogen complexes overcoming strength–ductility trade-off in an additively manufactured high-entropy alloy

ABSTRACT Strength and ductility were simultaneously enhanced in the additively manufactured CoCrFeMnNi high-entropy alloy by laser powder bed fusion (LBPF) under reactive N2 atmosphere. It was found that nitrogen atoms picked up during additive manufacturing line-up to form ordered nitrogen complexes (ONCs) in the octahedral interstitial position of the HEA matrix. Dislocation multiplication is then facilitated by the formation of ONCs during LPBF, leading to a higher dislocation density with smaller dislocation cells. Dislocation strengthening, combined with interstitial strengthening, endows the additively manufactured HEA with the yielding strength of 690 MPa, 15% higher than that of the counterparts fabricated under inert atmosphere. More interestingly, the ONCs stimulate dislocation nucleation and engender more heterogeneous microstructure, giving rise to an outstanding ductility of 15.3%, with an increment of 34%. As a result, the strength–ductility trade-off was successfully reversed by the nitrogen doping during LPBF under reactive atmosphere.
CircRNA_ACAP2 Suppresses EMT in Head and Neck Squamous Cell Carcinoma by Targeting the miR-21-5p/STAT3 Signaling Axis

Circular RNAs (circRNAs) contain microRNA (miRNA)-specific binding sites and can function as miRNA sponges to regulate gene expression by suppressing the inhibitory effect of miRNAs on their target genes. MiR-21-5p has been reported to be involved in the development of head and neck squamous cell carcinoma (HNSCC) and plays an important role in the activation of epithelial-mesenchymal transition (EMT). However, the upstream regulatory mechanism and downstream targets of miR-21-5p in tumor cells remain unknown. CircRNA_ACAP2 inhibits the function of miR-21-5p by binding to its specific binding sites in HNSCC cells. Overexpression of CircRNA_ACAP2 inhibits the proliferation and migration of HNSCC cells, while downregulation of CircRNA_ACAP2 has the opposite effect. STAT3 is a direct target gene of miR-21-5p and a transcription factor of ZEB1. We demonstrate that CircRNA_ACAP2 functions as a tumor suppressor gene in HNSCC and that its function is regulated via the miR-21-5p/STAT3 signaling axis.
Improved handoff quality and reduction in adverse events following implementation of a Spanish-language version of the I-PASS bundle for pediatric hospitalized patients in Argentina

Introduction communication errors between medical personnel are known to be a leading source of adverse events (AEs). The implementation of teamwork training together with the use of a standardized handoff bundle has previously shown to reduce the number of AEs. However, the applicability of this program in spanish-speaker countries remains unclear. Objective to assess whether the exploratory implementation of I-PASS bundle in an Argentine pediatric hospital is associated with a reduction in the rate of AEs. Methods Design: an exploratory, uncontrolled, pre-post study. Population and sample: medical records (MR), medical prescriptions, and physician reports were reviewed in two clinical wards of the "Hospital General de Niños Pedro de Elizalde". Intervention: I-PASS Spanish version, an standardized handoff bundle consists in: a mnemonics, an introductory workshop, a written handoff tool, simulation sessions, and structured observations with feedback. Results we reviewed 264 MR. Preventable AEs decreased by 62.8% between pre-intervention and post-intervention period (12.1 vs 4.5 AEs/100 admissions; IC95: 0.010; 0.142; [p = 0.025]). Adherence to the use of quality handoff key elements increased significantly, from 25% to 61% in post-intervention period (p = 0.0001). Handoff duration did not change significantly (5.5 ± 0.2 vs 5.3 ± 0.3 minutes per patient [p = 0.59]). Conclusion Implementation of an I-PASS Spanish version was associated with a significant reduction in the rate of AEs and with improvements in handoff quality; without changes in duration.
Education for All: How Schooling Is Creating Social Changes for Lowered-Caste Girls in Rural India

Arguments for the expansion of formal schooling have long focused on individual outcomes from schooling, including increasing income, reducing poverty, delaying marriage, and improving health, particularly for girls and women. For nearly three decades now, global education agendas have supported girls’ education in an effort to achieve these outcomes. A large body of research analyzes girls’ individual empowerment from schooling, but less attention is given to how schooling is creating change in families and communities, particularly for lowered-caste girls in India. This article places longitudinal data from a three-year qualitative interview study of schoolgirls in Rajasthan alongside qualitative life-history interviews of girls who completed secondary school in Uttarakhand to understand how schooling affects social changes for lower castes. The analysis, using an intersectional and relational approach, illustrates how girls’ schooling shifts kin and caste relations connected to marriage and work but in ways that do not transform the stickiness of caste and gender norms. We argue that educational policies and programs must attend to the ways in which caste is implicated in achieving outcomes of delayed marriage and formal employment for lowered-caste girls in Indian communities if schooling is to create positive social change.
AChRs Degeneration at NMJ in Aging-Associated Sarcopenia–A Systematic Review

Sarcopenia is an aging process with a decline of skeletal muscle mass and function, which is a challenging public health problem with reduced quality of life in patients. The endplate, the post-synaptic part of the neuromuscular junction (NMJ), occupies 0.1% of the myofiber surface area only, but is composed of millions of acetylcholine receptors (AChRs) that are efficient in binding to acetylcholine (ACh) and triggering skeletal muscle contraction. This systematic review aims to examine aging-associated alterations of post-synaptic AChRs, including morphology, function and related gene expression. A systematic literature search was conducted in PubMed, Embase and Web of Science with relevant keywords by two independent reviewers. Original pre-clinical and clinical studies regarding AChRs changes during aging with available full text and written in English were included. Information was extracted from the included studies for further review. In total, 30 articles were included. Various parameters assessing AChRs alterations by radioassay, immunofluorescence, electrophysiology and mechanical test were reported. Endplate fragmentation and denervation were common in old skeletal muscles during aging. To ensure efficient NMJ transmission and force generation, type I or IIb muscle fibers tended to have increased ACh quanta releasing after electrical stimulations, while type IIa muscle fibers tended to have stronger binding between ACh and AChRs, but the overall function of AChRs was reduced during aging. Alterations of AChRs area depended on muscle type, species and the progress of muscle atrophy and type I muscles fibers tended to demonstrate enlarging AChRs areas. Myogenic regulator factors (MRFs) can regulate the expression of AChRs subunits, while decreased MRF4 may lead to expression changes of AChRs subunits during aging. Sarcoglycan-α can delay low-density lipoprotein receptor-related protein 4 (LRP4) degradation. This protein was increased in old muscles but still cannot suppress the degradation of LRP4. Investigating the role of these AChRs-related genes in the process of aging may provide a potential target to treat sarcopenia.
Diffusing a Movement: An Analysis of Strategic Communication in a Transnational Movement

ABSTRACT This research explores how and by which mechanisms and processes a social movement diffuses to other countries or regions and the role of communication management in this spread. Findings suggest activists and advocates involved in the diffusion process can be understood as strategic translators whose work is locally oriented, but also whose connections and frames of reference are transnational. Activists and advocates are not merely receivers of information; rather, they are active seekers who engage with transnational ideas, information, and connections.
Energy transfer in supramolecular assemblies of oligo(p-phenylene vinylene)s terminated poly(propylene imine) dendrimers

Poly(propylene imine) dendrimers have been functionalized with π-conjugated oligo(p-phenylene vinylene)s (OPV's) through an amide linkage and are fully characterized. In solution the dendrimers behave as globular entities without specific interactions between the OPV units. The OPV dendrimers have an amphiphilic nature and self-assemble at the air−water interface forming stable monolayers in which the dendritic surfactants presumably adopt a cylindrical shape; all the OPV's are aligned perpendicular to the water surface, and the dendritic poly(propylene imine) cores face the aqueous phase. Optical spectra taken from Langmuir−Blodgett films show a small blue shift indicative of interactions between the OPV units. Spin-coated homogeneous thin films could be obtained from solutions containing dendrimers loaded with dyes. The optical properties of these films are similar to the Langmuir−Blodgett films which points to the same type of organization of the OPV's. The OPV dendrimers are effective extractants of a.
Prevalence and Cognitive Profiles of Children With Comorbid Literacy and Motor Disorders

There is a high prevalence of comorbidity between neurodevelopmental disorders. Contemporary research of these comorbidities has led to the development of multifactorial theories of causation, including the multiple deficit model (MDM). While several combinations of disorders have been investigated, the nature of association between literacy and motor disorders remains poorly understood. Comorbid literacy and motor disorders were the focus of the two present studies. In Study 1, we examined the prevalence of comorbid literacy and motor difficulties relative to isolated literacy and motor difficulties in a community sample (N = 605). The prevalence of comorbidity was five times greater than expected by chance alone, implying some relationship between difficulties. In Study 2, we examined the cognitive profiles of children with literacy and motor disorders amongst a subsample of children from Study 1 (N = 153). Children with literacy disorder had deficits in phonological processing, selective attention, and memory whilst children with motor disorder had deficits in visuospatial processing and memory, suggesting the disorders should be considered to have both independent and shared (memory) cognitive risk factors. Children with comorbid literacy and motor disorder demonstrated an additive combination of these deficits. Together, these findings are consistent with predictions from the MDM.
Psychological Nursing of Patients With Stroke in China: A Systematic Review and Meta-Analysis

The present study aimed to evaluate the efficacy of psychological nursing of patients with stroke in China. The Embase, PubMed, Cochrane Library, CNKI, and Wanfang databases were searched from inception to February 1, 2020. Randomized controlled trials (RCTs) reporting the efficacy of psychological nursing of patients with stroke were included. Revman 5.3 and Stata 15.0 were used for data analysis. Twelve RCTs and 1,013 patients with stroke were included in this systematic review and meta-analysis. The results revealed a significant difference in the Hamilton depression score between the psychological nursing and usual care groups. The meta-analysis of three studies (n = 235) that used a depressive symptom control of ≥25% as the outcome measure showed a significant difference between the two groups. In addition, significant differences were detected in the National Institute of Health stroke scale score and activities of daily living score between the two groups. The present meta-analysis suggests that in China, compared to the usual care, psychological nursing is more effective for alleviating depressive symptoms, improving neurological rehabilitation, and recovering the ability of daily life.
Understanding the Effects of Antecedents on Continuance Intention to Gather Food Safety Information on Websites

Virtual community websites are one of the applications that provide a platform for people with common interests to extend their social relations in social media. With the proliferation of food safety incidents in recent years, social media has often been a major channel for public engagement in risk communication because of its social networking and immediate interaction. To understand the users’ needs and satisfaction, this study proposed a model to develop and evaluate the antecedents of continuance intention toward food safety information from social media. Based on the questionnaire collected from 289 Facebook users, this study assessed the integrated model of the expectation-confirmation theory and technology acceptance model with technology readiness as moderator. The results showed that the perceived ease-of-use, usefulness, and confirmation indirectly affected social media continuance usage intention through satisfaction; perceived ease-of-use, usefulness, and satisfaction were the direct determinants that affected the users’ social media continuance intention. Furthermore, positive technology readiness had significant effects on the relationship between the perceived ease-of-use, usefulness, confirmation, satisfaction, and continuance intention toward food safety information. This study contributes some important suggestions and managerial implications for food safety promotion providers, practitioners, and academics in the food industry, and social media environment.
Innsbruck Teleportation Experiment in the Wigner Formalism: A Realistic Description Based on the Role of the Zero-Point Field

In this article, an undulatory description of the Innsbruck teleportation experiment is given, grounded in the role of the zero-point field (ZPF). The Wigner approach in the Heisenberg picture is used, so that the quadruple correlations of the field, along with the subtraction of the zero-point intensity at the detectors, are shown to be the essential ingredients that replace entanglement and collapse. This study contrasts sharply with the standard particle-like analysis and offers the possibility of understanding the hidden mechanism of teleportation, relying on vacuum amplitudes as hidden variables.
Assessment of Safety and Probiotic Traits of Enterococcus durans OSY-EGY, Isolated From Egyptian Artisanal Cheese, Using Comparative Genomics and Phenotypic Analyses

An Enterococcus durans strain, designated OSY-EGY, was previously isolated from artisanal cheese. In this work, comparative genomic and phenotypic analyses were utilized to assess the safety characteristics and probiotic traits of the bacterium. The comparative genomic analysis revealed that the strain is distantly related to potentially pathogenic Enterococcus spp. The genome was devoid of genes encoding acquired antibiotic resistance or marker virulence factors associated with Enterococcus spp. Phenotypically, the bacterium is susceptible to vancomycin, ampicillin, tetracycline, chloramphenicol, and aminoglycosides and does not have any hemolytic or gelatinase activity, or cytotoxic effect on Caco-2 cells. Altogether, these findings confirm the lack of hazardous traits in E. durans OSY-EGY. Mining E. durans OSY-EGY genome, for probiotic-related sequences, revealed genes associated with acid and bile salts tolerance, adhesion, competitiveness, antioxidant activitiy, antimicrobial activity, essential amino acids production, and vitamins biosynthesis. Phenotypically, E. durans OSY-EGY was tolerant to acidic pH (3.0), and presence of 0.3% bile salts. The bacterium showed adhesion capability to Caco-2 cells, cholesterol-lowering effect, DPPH scavenging activity, and antimicrobial activity against several Gram-positive pathogenic bacteria. Based on the current work, we propose that E. durans OSY-EGY is a potentially safe strain with desirable probiotic and antimicrobial traits. Thus, the investigated strain could be a promising candidate for several industrial applications.