Miracle-dz/UniFAR-FTUs huggingface dataset:
Using the GY* trait interaction in ecological field trials to evaluate grain yield of wheat varieties

Gubatov, T. , Tsenov, N. & Yanchev, I. (2021). Using the GY* trait interaction in ecological field trials to evaluate grain yield of wheat varieties. Bulg. J. Agric. Sci., 27 (2), 333–341 Setting and purpose: The purpose of this study is to investigate the possibility of an integral grain yield estimation by taking into account the genotype*environment interaction of yield traits in winter common wheat. Methods: At three main locations for the grain production in Bulgaria, 40 winter common wheat varieties were studied. Several productivity traits have been studied as follows: height of stem (HOS), number of productive tillers per m2 (NPT); number of grains per spike (NGS); thousand grain weight (TGW), weights of grain per spike (WGS), the number of grains per m2 (NGm), total above-ground biomass (TBM), harvest index (HI) and grain yield (GY) itself. A new methodology is used to assess the behaviour of each of the varieties, based on the relationship of its grain yield with some productivity traits, by measuring their change in different environmental conditions. Key results: The interaction of genotype x environment is essential for each of the tested traits. The variation of each of them is examined against the background of the others, and then evaluated through its relationship to grain yield. An integrated assessment of varieties is applied through the interaction of their traits and yield components (GY*T) with environmental conditions. Nevertheless of the close means of traits in the tested varieties, a significant difference was found between them. Conclusions: The established Mean Superiority Index (MSI) allows them to be properly stacked and grouped versus check varieties. The approach applied may group successfully varieties by traits that effect grain yields. The reasons for the specific grain yield of each of the varieties are analyzed by the combination of some character, which are dynamically variable according to the environments. Evaluation of a large number of varieties is fully possible by using the GY*trait approach that allows determination of their suitability for production and breeding value, as well.
PRESSURE DROP IN FIXED, EXPANDED AND FLUIDIZED BEDS, PACKED COLUMNS AND STATIC MIXERS - A UNIFIED APPROACH

On the basis of force and energy balance, a generalized approach has been developed for the prediction of pressure drop in fixed, expanded and fluidized beds, packed columns and static mixers. It has been shown that the Ergun type equation can be derived from first principles. i) Pressure drop in fixed, fluidized and expanded beds: Spherical particles
Bioinformatics analysis reveals that ANXA1 and SPINK5 are novel tumor suppressor genes in patients with oral squamous cell carcinoma

Background Oral squamous cell carcinoma (OSCC) is a solid tumor of squamous epithelial origin. Currently, surgery is still the main treatment for OSCC, with radiotherapy and chemotherapy as important adjuvant treatments. However, the problem of poor prognosis of OSCC patients still exists in clinical practice. To explore further potential biomarkers or treatment targets in OSCC patients, this study used a high-throughput gene expression database to study the potential molecular mechanisms of OSCC carcinogenesis. Methods The GEO database related to OSCC was searched and analyzed using GEO2R. Oncomine and the Human Protein Atlas were used to evaluate the expression level of differentially-expressed genes (DEGs). The cBioPortal dataset was used to analyze the mutations of the potential DEGs and patient survival. Results Three GEO datasets, GSE146483, GSE138206, and GSE148944, were downloaded and 7 DEGs were found in common in OSCC tissues. Using Oncomine and the Human Protein Atlas, ANXA1, IL1RN, and SPINK5 were decreased in cancer tissues, while protein levels of APOE and IFI35 were increased accordingly. Interestingly, low levels of ANXA1 and SPINKS were associated with the TNM stage of OSCC patients. No mutations in DEGs were found in OSCC patients, based on the cBioPortal dataset. Survival analysis indicated OSCC patients with high MSR1 had poor overall survival (OS), while low expression of CXCR4, ANXA1, IL1RN, and SPINK5 also predicted poor OS in OSCC patients. Conclusions Our findings uncovered 7 potential biomarkers of OSCC patients, with ANXA1 and SPINK5 serving as potential tumor suppressor genes in OSCC.
Determinants of Brand Loyalty: Survey of Wardah Cosmetics Consumer in Jabodetabek, Indonesia

This study tries to explore the determinants of Wardah cosmetics brand loyalty in Jabodetabek Indonesia. The independent variable is product quality, service quality, promotion and customer satisfaction. A sample of 100 respondents in Jabodetabek area & the sampling technique is convenience sampling (which includes whoever is found in accordance with the focus of research). The technique to get data is questionnaire, the scale used is a Likert scale where the answers are given a score of one to five. The results showed that product quality & consumer satisfaction had a significant effect on Wardah brand cosmetic loyalty while service quality and promotion had no significant effect on Wardah cosmetics brand loyalty.
The Role of Serum miR-497 on the Predictive Index of Early Diagnosis and Poor Prognosis of Atherosclerosis Cerebral Infarction

Background: Serum miR-497 can be used as a predictive index of the early diagnosis and poor prognosis of atherosclerosis cerebral infarction (ATCI). Methods: Overall, 135 ATCI patients, treated in The Second Affiliated Hospital of Nantong University, Nantong 226001, P.R. China from Apr 2012 to Jan 2015, were included in ATCI group. Whereas, 77 patients with non-atherosclerosis cerebral infarction were put in the control group. RT-qPCR was performed for detecting serum miR-497 expression, whose relationship with the patients’ clinicopathological parameters was analyzed. Receiver operating characteristic (ROC) curves were plotted to evaluate values of serum miR-497 for diagnosing ATCI patients and their 3-year and 5-year overall survival rates (OSRs). Cox regression analysis was conducted on prognostic factors of ATCI patients. Results: miR-497 remarkably rose in the serum of ATCI patients, and was correlated with histories of hypertension, smoking and diabetes mellitus (DM). Its areas under curves (AUCs) for diagnosing these pathological parameters were 0.803, 0.817 and 0.819, respectively. Its expression was higher in the serum of the patients with recurrence and poor prognoses. Its AUCs for predicting the two conditions were 0.924 and 0.937, respectively. The 3- and 5-year OSRs of patients with low expression were remarkably higher than those of patients with high expression. Conclusion: miR-497 and histories of hypertension, smoking and DM were independent prognostic factors affecting the 3-year OSR of ATCI patients. miR-497 expression rises in ATCI patients, so this miR is expected to become a serum diagnostic marker for ATCI.
Racial Socialization in Non-Hispanic White American Families: An Exploration of the Role of Parental Racial-Ethnic Socialization

RACIAL SOCIALIZATION IN NON-HISPANIC WHITE AMERICAN FAMILIES: AN EXPLORATION OF THE ROLE OF PARENTAL RACIAL-ETHNIC SOCIALIZATION Julia Carmen Rodil Old Dominion University, 2021 Director: Dr. Alan Meca Racial-ethnic socialization is a largely unstudied topic for White Americans. Most of the research on racial-ethnic socialization (RES) focuses on minority populations, but more literature is starting to focus on RES in White individuals. However, the mechanisms by which RES messages are transmitted are understudied. This study examined how prior parental RES strategies (i.e., egalitarianism, history of other groups, group differences, preparation for bias, general discrimination, and discrimination against other groups) impacted White college students’ own attitudes towards ethnic-racial minorities (i.e., racist, colorblind, and multicultural) and how these attitudes influenced inclusive (and non-inclusive) behavior, psychosocial costs of racism (White empathic reactions towards racism, White guilt, and White fear of others), and implicit biases. Findings showed that group differences and preparation for bias strategies were significantly associated with racist and color-blind attitudes. Results for socialization strategies regarding egalitarian messages and discrimination were mixed. Racist and color-blind attitudes resulted in less inclusive behavior and mixed findings for psychosocial costs (less guilt, less empathy, more fear), whereas multicultural attitudes resulted in less psychosocial costs (less fear and guilt). Results suggest that colorblindness is a particularly dangerous racial attitude, as it is complicit in perpetuating racism by failing to address the reality of racial inequality. The results
Role of Mitochondrial Dynamics in Microglial Activation and Metabolic Switch

Microglia act as sensors of injury in the brain, favoring its homeostasis. Their activation and polarization toward a proinflammatory phenotype are associated with injury and disease. These processes are linked to a metabolic reprogramming of the cells, characterized by high rates of glycolysis and suppressed oxidative phosphorylation. This metabolic switch can be reproduced in vitro by microglial stimulation with LPS plus IFN-γ. To understand the mechanisms regulating mitochondrial respiration abolishment, we examined potential alterations in mitochondrial features during this switch using rat primary microglia. Cells did not show any change in mitochondrial membrane potential, suggesting a limited impact in the mitochondrial viability. We provide evidence that reverse operation of F0F1-ATP synthase contributes to mitochondrial membrane potential. In addition, we studied the possible implication of mitochondrial dynamics in the metabolic switch using the mitochondrial division inhibitor-1 (Mdivi-1), which blocks dynamin-related protein 1 (Drp1)–dependent mitochondrial fission. Mdivi-1 significantly reduced the expression of proinflammatory markers in LPS plus IFN-γ–treated microglia. However, this inhibition did not lead to a recovery of the oxidative phosphorylation ablation by LPS plus IFN-γ or to a microglia repolarization. Altogether, these results suggest that Drp1-dependent mitochondrial fission, although potentially involved in microglial activation, does not play an essential role in metabolic reprogramming and repolarization of microglia.
Evaluation of Spatio-Temporal Land Use and Land Cover Dynamics Using Geospatial Technologies: The Case of Majang Zone, Ethiopia

The dynamics of land use-land cover changes is one of the phenomena which interweave the socioeconomic, political, and environmental issues in Ethiopia. This study investigated the land use-land cover (LULC) changes in the Majang Zone of Gambela Region, Ethiopia over a period of 33 years from 1985 to 2018. Four sets of Landsat imageries (i.e.,1985, 1996, 2007, and 2018) were the input data from which LULC maps were produced and analyzed using remote sensing and GIS applications. Concurrently, key informants’ interviews, focus group discussions, and questionnaires were used to identify and describe the drivers of LULC changes. The LULC change analysis revealed a continuous decline of forest lands throughout the first (1985-1996), second (1996-2007), and third (2007-2018) study periods by 10.7%, 17%, and 31.5%, respectively. Similarly, shrub/grasslands decreased in all consecutive three periods by 22%, 29.5%, and 63.7%. On the contrary, settlement areas increased by 53.6% in the first, 102.4% in the second, and 65% in the third period. Agricultural lands also expanded over the study periods by 34.8%, 17.6%, and 26.5%, respectively. The overall results of the analysis showed that between the years 1985 and 2018, forest lands, shrub/grasslands, and water bodies declined by 49.7%, 80%, and 42.3%, while agricultural lands and settlement areas increased by 100.6%, and 413%, respectively. Along with the dynamics, population pressure, land tenure policy, cropland expansion, and settlement expansion were identified as the leading causes that triggered LULC changes observed over the 33 years of the study period. The findings indicated that the Majang zone has been subjected to extensive agricultural investments and settlement expansions at the cost of forest lands and shrub/grasslands. Therefore, it is important to prioritize and design strategies for better LULC systems and natural resource conservation for integrated and sustainable development.
The Roles of CSR and Marketing Ethics in FMCG Company’s Reputation During the Covid-19 Pandemic

This study aimed to reveal whether Corporate Social Responsibility (CSR) and marketing ethics have certain roles in the reputation of Fast-Moving Consumer Goods (FMCG) Company during the Covid-19 pandemic. This study used survey method by collecting data through questionnaire. The respondents in this study were 128 consumers of FMCG and acquired by using the convenience sampling technique and the data was then analysed using SPSS. The result of this study showed that CSR and marketing ethics positively and significantly affect the FMCG company’s reputation, either partially or simultaneously during this Covid-19 pandemic.
Spatial analysis of long‐term effects of different tillage practices based on penetration resistance

Measuring penetration resistance (PR) is a common technique for evaluating the effects of field management on soils. This study focuses on the effects of long‐term tillage on the spatial distribution of PR, comparing reduced and conventional tillage (CT) practices. The study site, located in Lower Saxony (Germany), has been subdivided into three plots, with one plot having been managed conventionally, whereas reduced tillage (RT) practices have been applied to the other two. In total, PR was measured at 63 randomly selected points. The PR data were stepwise interpolated using kriging with external drift. Core samples have been taken at 20 additional sites. The results show significant differences in PR between the different tillage practices. Within the conventionally managed plot, PR ranges to 2.3 MPa less in the topsoil than under RT. However, measured saturated hydraulic conductivity and amount of biopores at the depth of 30–35 cm are significantly greater under RT, indicating improved soil properties under RT. Comparisons between the headlands (HL) and the inner field point out the effects of intense field traffic in the HL, where maximum PR values of about 6 MPa have been measured. The spatial prediction of PR values show that long‐term effects of different tillage practices result in clearly structured patterns between CT and RT and the HL. Combining extensive PR measurements and point measurements of additional soil properties supports an adequate interpretation of PR data and can lead to fieldwide derivation of soil functions influenced by field management.
THE EFFECTIVE TEACHER OF ENGLISH: AN EXPLORATORY QUALITATIVE STUDY OF INDIAN ENGLISH TEACHERS’ BELIEFS

Introduction Teachers’ beliefs about teaching and learning are known to be important influences, both on their classroom practice and on the likelihood of their being receptive to innovation and change (Borg 2018; Richardson 1996). There is evidence that these beliefs vary between countries and cultures (Alexander 2000; Schweisfurth 2013), one of the factors that has caused a number of authors, including within foreign and second language teaching, to argue for the need for contextappropriate pedagogy (e.g. Holliday 1994). Despite India today being the largest education system in the world (Anderson & Lightfoot 2019), it is notable that very little research has been conducted into Indian teachers’ beliefs (Brinkmann 2015), a clear gap in the research literature that this study aims to fill. Particularly in the field of English language teaching, which has a deep-rooted history in India’s colonial period (Kumar 2005) and frequently involves the combined teaching of language and literature, such research is likely to inform the steady stream of educational initiatives currently taking place in India (e.g. British Council 2016; Mody 2013; TEJAS 2019), the success of which will depend, in part, on the extent of their compatibility with teachers’ prior beliefs (Lamb 1995). The study will also inform understandings of the relationship between teachers’ beliefs and (socio)cultural contexts (Alexander 2000; Hu 2002). In order to achieve these aims, this study investigates the beliefs of English language teachers and teacher educators in India regarding the classroom practices, personal attributes and beliefs of an imagined effective Indian teacher of English through a specific community of practice (CoP; Lave & Wenger 1991). It uses an original, qualitative survey instrument to produce an effective teacher ‘prototype’ (Sternberg & Horvath 1995), comparing this to prior studies, both in India and other countries, and discussing implications for teacher education and development.
Rebooting Virtual Memory with Midgard

Computer systems designers are building cache hierarchies with higher capacity to capture the ever-increasing working sets of modern workloads. Cache hierarchies with higher capacity improve system performance but shift the performance bottleneck to address translation. We propose Midgard, an intermediate address space between the virtual and the physical address spaces, to mitigate address translation overheads without program-level changes.Midgard leverages the operating system concept of virtual memory areas (VMAs) to realize a single Midgard address space where VMAs of all processes can be uniquely mapped. The Midgard address space serves as the namespace for all data in a coherence domain and the cache hierarchy. Because real-world workloads use far fewer VMAs than pages to represent their virtual address space, virtual to Midgard translation is achieved with hardware structures that are much smaller than TLB hierarchies. Costlier Midgard to physical address translations are needed only on LLC misses, which become much less frequent with larger caches. As a consequence, Midgard shows that instead of amplifying address translation overheads, memory hierarchies with large caches can reduce address translation overheads.Our evaluation shows that Midgard achieves only 5% higher address translation overhead as compared to traditional TLB hierarchies for 4KB pages when using a 16MB aggregate LLC. Midgard also breaks even with traditional TLB hierarchies for 2MB pages when using a 256MB aggregate LLC. For cache hierarchies with higher capacity, Midgard’s address translation overhead drops to near zero as secondary and tertiary data working sets fit in the LLC, while traditional TLBs suffer even higher degrees of address translation overhead.
Effect of Eight-Week Combined Strength-Balance Training on Muscle Strength, Balance and Quality of Life in Children with Monoplegic Cerebral Palsy

1 Assistant Professor, Department of Sport Sciences, Faculty of Social Sciences, Imam Khomeini International University, Qazvin, Iran 2 Ms of exercise physiology, Allame Gazvini Institute, Qazvin, Iran * Corresponding author: Abbas Sadeghi, Assistant Professor, Department of Sport Sciences, Faculty of Social Sciences, Imam Khomeini International University, Qazvin, Iran. E-mail: sadeghi@soc.ikiu. ac.ir How to Cite this Article: Sadeghi A, Pourrazi H, Mafi S. Effect of Eight-Week Combined Strength-Balance Training on Muscle Strength, Balance and Quality of Life in Children with Monoplegic Cerebral Palsy. J North Khorasan Univ Med Sci. 2020;7(2):52-62. DOI: 10.29252/ijrn.7. 2.52
Thinking between disciplines: an aesthetics of knowledge1

What should be understood by the invocation of an ‘aesthetics of knowledge’? It is clearly not a matter of saying that the forms of knowledge must take on an aesthetic dimension. The expression presupposes that such a dimension does not have to be added as a supplementary ornament, that it is there in every sense as an immanent given of knowledge. It remains to be seen what this implies. The thesis that I would like to present is simple: to speak of an aesthetic dimension of knowledge is to speak of a dimension of ignorance which divides the idea and the practise of knowledge themselves.
University of Birmingham Self-management of health care behaviors for COPD: a systematic review and meta-analysis

Purpose: This systematic review aimed to identify the most effective components of interventions to facilitate self-management of health care behaviors for patients with COPD. Methods: We used standard review methods with a systematic search to May 2012 for randomized controlled trials of self-management interventions reporting hospital admissions or health-related quality of life (HRQoL). Mean differences (MD), hazard ratios, and 95% confidence intervals (CIs) were calculated and pooled using random-effects meta-analyses. Effects among different subgroups of interventions were explored including single/multiple components and multicomponent interventions with/without exercise. Results: One hundred and seventy-three randomized controlled trials were identified. Self-management interventions had a minimal effect on hospital admission rates. Multicomponent interventions improved HRQoL (studies with follow-up  6 months St George’s Respiratory Questionnaire (MD 2.40, 95% CI 0.75–4.04, I 2 57.9). Exercise was an effective individual component (St George’s Respiratory Questionnaire at 3 months MD 4.87, 95% CI 3.96–5.79, I 2 0%). Conclusion: While many self-management interventions increased HRQoL, little effect was seen on hospital admissions. More trials should report admissions and follow-up participants beyond the end of the intervention.
Does Earnings Management Matter for Strategy Research?

Strategic management research frequently seeks to explain variation in organizational performance using metrics such as accounting profits scaled by firm assets (ROA). A concern with accrual-based accounting methods, perhaps best illustrated by a large discontinuity in the distribution of ROA around zero for U.S. public firms, is that operational and accounting practices will artificially inflate/deflate accounting profit. In this manuscript we establish that such earnings management is common, introduces non-classical noise, and distorts our understanding of broad drivers of firm performance. We conclude with analysis showing that an alternative performance measure, Cash Flows from Operations on Assets (OCFOA), offers a robust vehicle for checking results using accounting profits.