Miracle-dz/UniFAR-FTUs huggingface dataset:
Mental Health Impact of the COVID-19 Pandemic on Mexican Population: A Systematic Review

The COVID-19 pandemic has had an impact on mental health in the general population, but no systematic synthesis of evidence of this effect has been undertaken for the Mexican population. Relevant studies were identified through the systematic search in five databases until December, 2021. The selection of studies and the evaluation of their methodological quality were performed in pairs. The Newcastle-Ottawa Scale (NOS) was used for study quality appraisal. The protocol of this systematic review was registered with PROSPERO (protocol ID: CRD42021278868). This review included 15 studies, which ranged from 252 to 9361 participants, with a total of 26,799 participants. The findings show that COVID-19 has an impact on the Mexican population’s mental health and is particularly associated with anxiety, depression, stress and distress. Females and younger age are risk factors for development mental health symptoms. Mitigating the negative effects of COVID-19 on mental health should be a public health priority in Mexico.
Strength Training in Climbing: A Systematic Review

Supplemental Digital Content is Available in the Text. Abstract Langer, K, Simon, C, and Wiemeyer, J. Strength training in climbing: A systematic review. J Strength Cond Res 37(3): 751–767, 2023—The aim of this review was to provide an overview of the state of research on strength training in climbing and to answer the question how climbing performance, maximum grip strength, upper-limb strength endurance, maximum upper-limb strength, and upper-limb power as dependent variables are affected by different types of training. Moreover, we addressed the question which training methods and training parameters are most effective in increasing climbing and bouldering performance. Searches of MEDLINE (PubMed), SPORTDiscus, ProQuest, and Google Scholar were conducted for studies that met the following criteria: (a) examining effects of training on at least one of the dependent variables, (b) controlled longitudinal design with pretest and posttest, and (c) detailed information on training parameters and subjects. Twelve studies were included into the review. The quality of the studies was rated according to the PEDro scale, and the training interventions were classified according to training method (maximum strength [MS], hypertrophy [HYP], and endurance [END]), specificity (specific, semispecific, and unspecific), and static or dynamic exercises. For 9 of the 12 studies, effect sizes were calculated and the treatments compared. The results showed (a) positive effects of strength training on all variables, (b) a trend toward a mixture of MS and HYP or END training, (c) a trend toward semispecific exercise, and (d) similar effects for dynamic and static exercise with a trend toward a mixture of both. Coaches and athletes are recommended to combine static and dynamic semispecific exercises in a HYP and MS or END training.
Nutritional and anti-gastro ulcerative role of the gum Arabic (Acacia senegal L.) compared to a reference drug

Background: As alcohol consumption increases, ethanol impacts ulcers as a factor that causes stomach mucosal invasion, which leads to stomach ulcers. Alcohol damages the stomach through a number of processes, including increased gastric secretion, the release of pro-inflammatory cytokines, and ethanol induces a variety of pathogenic events as it is associated with the formation of stomach ulcers.Objective: The goal of this study was to see if gum Arabic as a functional food could protect albino rats against ethanol-induced stomach damage.Materials and Methods: Six groups of 30 female albino rats were formed: normal control, ulcer control, omeprazole + ethanol, and groups 4, 5, and 6, which were given GA at 7.5, 12, 25 g/ kg/ day (bw), then lab rat were given 5 mL/kg /day (bw) ethanol orally for 30 days to cause stomach mucosal damage.Results: GA suppressed gastric inflammation by lowering TNF-α and IL-6 levels while increasing IL-10 levels. GA also improved HDL, total protein, albumin, and globulin levels while lowering cholesterol, triglycerides, VLDL-C, LDL-C, and phospholipids.Conclusion: These findings demonstrate that GA plays a protective role toward gastric mucosal injury in rats induced by ethanol, which in turn reduced the inflammatory response, and significantly reduced the hemorrhagic gastric lesions and the pH of the gastric contents. Keywords: Functional food, Alcoholic, polysaccharides, soluble fiber, tumor necrosis factor alpha, oxidative stress
Promising Colloidal Rhenium Disulfide Nanosheets: Preparation and Applications for In Vivo Breast Cancer Therapy

Photothermal therapy (PTT) has become an important therapeutic strategy in the treatment of cancer. However, exploring novel photothermal nanomaterials with satisfactory biocompatibility, high photothermal conversion efficiency, and efficient theranostic outcomes, remains a major challenge for satisfying clinical application. In this study, poly-ethylene glycol modified rhenium disulfide (PEG-ReS2) nanosheets are constructed by a simple-liquid phase exfoliation method. The PEG-ReS2 nanosheets were demonstrated to have good solubility, good biocompatibility, low toxicity, and strong capability of accumulating near-infrared (NIR) photons. Under 808 nm laser irradiation, the PEG-ReS2 nanosheets were found to have an excellent photothermal conversion efficiency (PTCE) of 42%. Moreover, the PEG-ReS2 nanosheets were demonstrated to be ideal photothermal transduction agents (PTAs), which promoted rapid cancer cell death in vitro and efficiently ablated tumors in vivo. Interestingly, the potential utility of up-regulation or down-regulation of miRNAs was proposed to evaluate the therapeutic outcomes of PEG-ReS2 nanosheets. The expression levels of a set of miRNAs in tumor-bearing mice were restored to normal levels after PTT therapy with PEG-ReS2 nanosheets. Both down-regulation miRNAs (miR-125a-5p, miR-34a-5p, miR-132-3p, and miR-148b-3p) and up-regulation miRNAs (miR-133a-3p, miR-200c-5p, miR-9-3p, and miR-150-3p) were suggested to be important clinical biomarkers for evaluating therapeutic outcomes of breast cancer-related PTT. This work highlights the great significance of PEG-ReS2 nanosheets as therapeutic nanoagents for cancer therapy.
Benzocaine and eugenol as anesthetics for Brycon hilarii - doi: 10.4025/actascianimsci.v35i2.16644

Anesthetic products are frequently employed during fish handling practices; however, the correct doses of the various chemicals for different species are still unknown. This study determined the ideal concentrations of benzocaine and eugenol as anesthetics used in Brycon hilarii juveniles. The fish were acquired from a commercial fish farm located in western Parana state, Brazil, totaling 104 juveniles, with average body weight and length of 50.04 ± 20.80 g and 16.30 ± 12.32 cm respectively. The study was carried out at the Aquiculture Laboratory from the Aquaculture Management Study Group - GEMAq at the West Parana State University. Five benzocaine concentrations (50.0, 100.0, 150.0, 200.0 and 250.0 mg L -1 ) and seven eugenol concentrations (50.0, 100.0, 150.0, 200.0, 250.0, 300.0 and 350 mg L -1 ) were evaluated in order to assess the induction time to anesthesia. The fish were transferred to anesthetic-free tanks to recover, and the time needed to return to normal activity was recorded. The best results were observed with the benzocaine dose of 100 mg L -1 and the eugenol dose between 100 and 150 mg L -1 .
Safety and efficacy of inclisiran in South African patients at high cardiovascular risk: A subanalysis of the ORION phase III clinical trials.

BACKGROUND Inclisiran significantly reduced low-density lipoprotein cholesterol (LDL-C) in individuals with heterozygous familial hypercholesterolaemia, established atherosclerotic cardiovascular disease (ASCVD) or ASCVD risk equivalents (type 2 diabetes, familial hypercholesterolaemia or a 10-year risk of a cardiovascular event ≥20%) in the ORION phase III clinical trials. Infrequent dosing at days 1, 90, 270 and 450 resulted in a mean LDL-C reduction of ~50%. A total of 298 participants from South Africa (SA) were enrolled. Local data are needed to support the use of inclisiran in the SA population, potentially addressing an unmet need for additional LDL-C-lowering therapies. Objectives. To analyse the ORION phase III trial data to assess the efficacy and safety of inclisiran in SA participants. Methods. ORION-9, 10 and 11 were randomised, double-blind, phase III trials. Participants were receiving maximally tolerated statins with or without other lipid-lowering therapies (excluding protein convertase subtilisin/kexin type 9 (PCSK9) inhibitors). Participants were randomised 1:1 to inclisiran sodium 300 mg/284 mg (free acid) or placebo administered at days 1, 90, 270 and 450. The co-primary endpoints were the LDL-C percentage change from baseline to day 510 and the time-averaged percentage change in LDL-C from baseline after day 90 up to day 540. Key secondary endpoints included the absolute change in LDL-C from baseline to day 510, the time-averaged absolute change from baseline after day 90 up to day 540, and changes in other lipids and lipoproteins. Results. The mean age of the participants was 58.6 years (56% male). The mean LDL-C level at baseline was 3.6 mmol/L. At day 510, inclisiran reduced LDL-C levels by 54.2% compared with placebo (95% confidence interval (CI) -61.3 - -47.2; p<0.0001). The corresponding time-averaged reduction in LDL-C was 52.8% (95% CI -57.9 - -47.8; p<0.0001). Treatment-emergent adverse events at the injection site were more common with inclisiran compared with placebo (10.1% v. 0.7%); however, all were mild or moderate in nature and none were persistent. Conclusion. Inclisiran, given in addition to maximally tolerated standard lipid-lowering therapy, is effective and safe and results in robust reductions in LDL-C in SA patients at high cardiovascular risk.
Development of Gluten-Free Cupcakes Enriched with Almond, Flaxseed, and Chickpea Flours

Background. The mixing of cereals and legumes with nuts and seeds can produce various products that can be optimal for consumption with respect to their nutritional density. The use of legumes in gluten-free foods is becoming very prominent with increase in advancement in food engineering and technology. This study was aimed to develop a gluten-free product (cupcake) enriched with chick pea flour, almonds, and flaxseeds for celiac disease patients. Materials and Methods. The procured raw material including almonds, chickpea flour, and flaxseeds was mixed in appropriate amounts, and cupcakes were formulated following a specified recipe. The cupcakes were divided in five groups based on their recipe. First one was wheat based; 2nd one was corn and rice based; and next 3 were chickpea, almond, and flaxseed based, respectively. The cupcakes were checked for their proximate analysis parameters (carbohydrate, protein, and nitrogen-free extract), gluten and heavy metals (lead, chromium, and arsenic), bacterial load (E. coli, total coliforms, salmonella, yeast, and molds), fatty acid, texture parameters (firmness, cohesiveness, gumminess, and chewiness), and physical parameters (weight, height, volume, and specific volume). All these parameters were compared with wheat-based cupcakes to assess the product’s quality. Results. The volume of intervention cupcakes was a bit low compared to wheat/rice-based cupcakes but the specific volume was comparable. In texture analysis, firmness, gumminess, and chewiness were enhanced in intervention cupcakes compared to control but cohesiveness was comparable also. The carbohydrate contents were significantly lower in intervention cupcakes 22–30% compared to control cupcakes. Protein, fiber, and fat contents were significantly higher 11–14, 8–10, and 40%, respectively, with improvement (2-3 folds) in calcium, zinc, and iron contents in intervention cupcakes. All the safety parameters including heavy metals and bacterial and fungal load were found normal. The sensory attributes like size and color were found to be less acceptable but odor and taste were comparatively high in formulated products. Conclusion. The use of chickpeas, almonds, and flaxseeds in high concentration was first-time used to formulate a recipe of gluten-free cupcake. These cupcakes were more nutritious compared to available conventional recipes. Apparently, no health hazard was found in these cupcakes. Some sensory characteristics of cupcakes were slightly lower and comparable to wheat/rice-based cupcakes.
Increase in Suspended Sediment Contents by a Storm Surge in Southern Bohai Sea, China

Most of the existing results were related to the impact of land storms on sediment, and few explained the impact of storms on sediment movement and its formation law from the mechanism. At present, the research on the impact of storm on sediment suspension on the North Bank of Longkou City in the south of Bohai Sea was not clear. Therefore, this study aimed to explore the formation and mechanism of storm on suspended sediment from the perspective of hydrodynamic characteristics and sediment distribution by monitoring the impact of storm on sediment suspension in the south of Bohai Sea. A storm with wind speeds of 4.5–13.5 m/s occurred in the coastal area of the north side of Longkou City located in Southern Bohai Sea in April, 2015. Suspended sediment samples were obtained using automatic samplers, and the results showed that the suspended sediment content was 7.8 mg/L under normal weather conditions, which reached 121.2 mg/L at the highest during the storm event. Waves and tides were synchronously observed by acoustic Doppler current meter. Wave height was more closely correlated with wind speed when the wind veered to north, and the maximum wave height was 243 cm. The reciprocating motion of the current at the sampling site was strong, with the maximum current speed of 43.8 cm/s and a water depth of 10 m. The results of laser analysis showed that the bottom sediments were composed of 92% sand and 8% silt, with a medium diameter of 0.102 mm. From the experimental observation and result analysis, it was known that the strong dynamic process during storm surge led to the movement of sediment surface and the resuspension of sediment.
PRECIPITATION AND UNDERSTORY VEGETATION DIVERSITY DRIVE VARIATIONS IN SOIL ORGANIC CARBON DENSITY: RESULTS FROM FIELD SURVEYS AND SATELLITE DATA OF TWO DIFFERENT PERIODS IN THE GREATER KHINGAN MOUNTAINS OF NORTHEAST CHINA

The forest ecosystem in Greater Khingan Mountains (GKM) is the largest primary forest in northern China. Accurate assessment of the regional carbon (C) pool of soils and analysis of the control factors are essential for setting appropriate forest management policies. Our study was designed to prove the hypothesis that forest soil acts as a C sink owing to continuous C accumulation, which results from constant biomass production within the GKM forests. We investigated topsoil (0-20 cm) C dynamics and diving force in GKM forests (both the Inner Mongolia and Heilongjiang sectors) based on field data from 2000 to 2019. The mean soil organic C density (SOCD) in the topsoil was 10.64 ± 0.83 kg C m across the GKM, and the increase rate was 0.15±0.05 kg C m y. Our results also demonstrated the critical role of precipitation and under vegetation diversity in shaping soil organic C dynamics across the GKM, suggesting that the relationship between the soil C cycle and temperature is unstable in northern ecosystems. Our results provided a new reference range for estimating surface soil C pools in GKM forests ecosystems based on field measurements.
Thermo-torsional buckling and postbuckling of thin FGM cylindrical shells with porosities and tangentially restrained edges

Abstract This paper aims to analyze the effects of porosities, tangential constraints of boundary edges and elevated temperature on the buckling and postbuckling behaviors of thin functionally graded cylindrical shells subjected to uniform torsion. The porosities are assumed to exist within functionally graded material (FGM) according to even and uneven distributions. The properties of constituents are assumed to be temperature dependent and effective properties of porous FGM are determined using a modified rule of mixture. Mathematical formulations are established within the framework of classical shell theory taking into account von Kármán–Donnell nonlinearity and elasticity of tangential edge constraints. Multi-term analytical solutions are assumed to satisfy simply supported boundary conditions and Galerkin method is used to determine buckling torsional load and load–deflection relation for postbuckling analysis. Numerical results show that porosities have remarkably deteriorative influences on the torsional buckling resistance and postbuckling load capacities of FGM cylindrical shells. This study also reveals that tangential edge constraints have pronouncedly beneficial and detrimental effects on the postbuckling strength of torsion-loaded porous FGM cylindrical shells at room and elevated temperatures, respectively.
Influence of Season and Sowing Method on the Growth and Yield of Lowland Rice (Oryza sativa L.) at Zigau Bauchi State

Field experiment was conducted at Goria farm Zigau, Shira Local Government Area of Bauchi State, Nigeria during the wet and dry seasons of 2015 and 2016 to study the influence of season and sowing method on the growth and yield of lowland rice. A lowland variety FARO 44 was used for the study. The treatments consisted of two seasons (dry and wet) and four different sowing methods (Transplanting, Dibbling, Drilling and Broadcasting). The treatments were laid in Randomized Complete Block Design (RCBD) replicated four times. The result revealed that growing the crop during the wet season produced significantly (p ≤ 0.01) taller plants than those of the dry season. Dry season sowing on the other hand, had significantly (p ≤ 0.01) more tillers, number of seeds per spike, spikes number per hill and grain yield (kg/ha) than the wet season rice production. At different sowing methods, transplanting produced a significantly (p ≤ 0.01) higher number of tillers per plant, number of seeds per spike, seed weight per spike and grain yield (kg/ha) than all the other sowing methods used. The result further revealed that the dibbling method of sowing significantly (p ≤ 0.01) gave higher number of spikes per hill than all other treatments studied. Rice farmers in the study area can therefore, in addition to their traditional wet season rice production, introduce dry season production which was observed to have high yield potential. Farmers are also advised to transplant their crop instead of their traditional broadcasting method or other methods for higher yield.
Layer-by-layer analysis: tribological behaviour of Ni60A coating on copper substrate prepared by plasma cladding

To further clarify the characteristics of plasma-cladded Ni60A coating on copper, the microstructure and wear behavior were analyzed layer by layer. Along the depth direction, the coating can be divided into three regions according to the difference of microstructure: upper, middle and bottom. The phase composition in different regions was the same (including γ-(Cu, Fe, Ni), Cr23C6, CrB and Ni3Si), and there was no obvious difference in the volume fraction of strengthening phases (Cr23C6 and CrB). Due to the stronger load-bearing capacity of larger-size strengthening phases, the wear resistance of middle region was slightly higher than that of upper region. However, the high copper content in bottom region led to a decrease in hardness and resistance to plastic shear, which significantly reduced the wear resistance (2.3 times lower than upper region). Chemical composition had a greater impact on the wear resistance than size and distribution uniformity of strengthening phases.
Promoting Adherence to Iron Chelation Treatment in Beta-Thalassemia Patients

Abstract Thalassaemia is one of the commonest inherited genetic disorders world-wide with around 25,000 births of the most severely affected transfusion dependent children annually. Patients with transfusion dependent thalassaemia require regular blood transfusions to maintain life but because of this will develop iron overload. To remove the excess iron, patients are required to take iron chelation therapy (ICT). ICT requires lifelong adherence to treatment to prevent end organ damage from developing. Many of these preventable complications make adherence to therapy more complex for patients. In this review, we focus on two commonly encountered patient scenarios and discuss how different psychological models and a relational theory can be used to understand and support adherence to treatment.
Music-mechanisms at the core of music therapy: Towards a format for a description of music therapy micro-interventions

ABSTRACT Introduction The quality and quantity of music therapy research are increasing, as are the number of systematic reviews and meta-analyses. However, the latter often define the effect of music therapy treatment as inconclusive. This is frequently due to a lack of clear description of the intervention or the core function of music. Clearly described music therapy interventions might lead to improved treatment fidelity. This article offers a possible solution in three parts. First, limitations in music therapy research are discussed. Second, the design for a format of a practice-based intervention description is explained. In the third part of the article, an example illustrates the use of the format. Method The suggested micro-intervention format could lead to a greater reliability in empirical research through the recognition of the working-mechanisms of music therapy intervention at a micro-level. The micro-intervention format was created in collaboration with practicing music therapists, Master students, and a board member for scientific innovation of a professional association. Results The micro-intervention format allows music therapists to describe music therapy interventions in detail, including the intervention and its musical working-mechanisms. The format is intended to guide music therapists to execute their intervention in comparable manners, which in the case of a scientific study could improve research fidelity. “Music therapeutic guidance to reduce agitation in dementia care using improvisation and familiar songs” is used to illustrate the micro-intervention format. Discussion Development and dissemination of music therapy micro-interventions could lead to improved research outcomes and strengthen the evidence-based foundation of the profession.
Stability and Asymmetry of Tide‐Influenced River Bifurcations

Bifurcations are important geomorphological features in tide‐influenced deltas. At bifurcations, river flow and tides distribute sediment over the channel network and determine the morphodynamic evolution of the entire delta. Using a one‐dimensional numerical model, we study the effects of tides on the morphological evolution of bifurcations from river‐dominated to tide‐dominated systems. In accordance with previous studies, bifurcations with small tidal influence, in which the flood flow hardly drives morphological change, have a larger range of Shields stress and width‐to‐depth ratio conditions for which symmetric bifurcations are stable to depth perturbations, compared to their river‐dominated counterparts. We extended the existing studies to tide‐dominated conditions. When bifurcations become increasingly tide‐dominated, the range of conditions under which balance discharge partition (symmetric morphology) can exist, shrinks. Under these conditions, the bed can also change during the flood phase and growth of the bed asymmetry is larger than the decay during ebb. However, the bed asymmetry in equilibrium becomes less pronounced with increasing tidal dominance. We conclude that tides reduce the tendency of closure and abandonment of one of the downstream channels compared to river‐dominated bifurcations, either by inhibiting the instability or by reducing asymmetry.