Miracle-dz/UniFAR-FTUs huggingface dataset:
Enhanced Recovery After Urogynecologic Surgery: A Survey of Patient Experience

Objectives The aim of this study was to identify which aspects/components of the enhanced recovery program (ERP) were associated with a positive patient surgical experience for patients undergoing urogynecologic surgery. Methods A total of 198 patients who underwent pelvic reconstructive surgery requiring hospital admission were invited to complete questionnaires modeled after the validated Consumer Assessment of Healthcare Providers and Systems Surgical Care Survey patient experience survey. Patients were asked about 3 phases of ERP interventions: (1) before surgery (patient education, carbohydrate loading), (2) during the hospital stay (pain control, nausea, early ambulation), and (3) after discharge (return of bladder and bowel function). Results One hundred patients completed the survey (51% response rate). Greater than 90% of patients rated their overall surgical experience favorably (≥8 on 1–10 scale) regardless of age (P = 0.98), race (P = 0.26), education level (P = 0.12), perception of overall health (P = 0.17), or number of prior surgical procedures (P = 0.86). Ninety-two percent of patients reported that preoperative teaching about surgery was “very helpful,” and specifically 90% reported that the ERP educational handbook was useful. Patients who reported a poor perception of their overall mental health were more likely to rate their surgical experience less favorably (<8 on 1–10 scale; P = 0.01), as were patients who left the hospital with a Foley catheter (P = 0.03). Conclusions Greater than 90% of women surveyed who rated undergoing inpatient pelvic reconstructive surgery positively perceived their surgical experience within the ERP. The majority of patients who had a positive perception of the perioperative experience found the preoperative patient education useful.
Assessment of Fatigue Life and Stiffness of Asphalt Concrete After Implementation of Additives

Modifying asphalt binder with additives can enhance the overall physical properties of asphalt concrete. In the present investigation, an attempt has been made to use 2 % of silica fumes and 4 % of fly ash class F for modification of asphalt binder in wet process. Asphalt concrete wearing course slab samples have been prepared under roller compaction. The beam specimens of 400 mm length and 50 mm height and 63 mm width were extracted from the slab samples. The beam specimens were subjected to the four-point repeated flexural bending beam test. The flexural stiffness was calculated under three constant micro strain levels of (250, 400, and 750). The fatigue life was monitored in terms the number of load repetitions to reach the required reduction in stiffness of 50 %. It was concluded that the flexural stiffness increases by (11, and 15) %, (17.7, and 63.6) %, (57.2, and 65) % when 2% of silica fumes or 4 % of fly ash are implemented and the specimen’s practices 750, 400, and 250 micro strain levels respectively. However, the fatigue life increases by (40, and 72.8) %, (115, and 220.6) %, (46, and 94.6) % when 2% of silica fumes or 4 % of fly ash are implemented and the specimen’s practices 750, 400, and 250 micro strain levels respectively. It is recommended to use modified binder with silica fumes and fly ash in asphalt concrete to enhance the fatigue life and stiffness.
Intercultural Human Resource Management Practices and Employees Satisfaction in Quoted Food and Beverages MNC in Nigeria

This study assessed the impact of intercultural human resource management practices (Recruitment and Selection practices, Employee empowerment practice, and Compensation practice) on employees’ satisfaction in food and beverages MNCs in Nigeria. The study adopted descriptive survey research design. The target population comprises 6,356 staff of quoted food and beverages MNCs in Nigeria. Taro Yamane statistical formulae was used to determine the sample size of 1,568. Purposive sampling technique was used to determine the respondents which included Nigerians and Other Nationals working in the quoted food and beverages MNCs. A structured survey questionnaire was adapted, validated, and used for the construct ranged between 0.61 and 0.93. The response rate to the 1,568 copies of the questionnaire administered was 74%. Data were analysed using descriptive and inferential (Student T-test of multiple regression analysis) statistics. Hypotheses were tested at 0.05 level of significance using SPSS 20. Findings revealed that, Recruitment and Selection practices, Employee empowerment practice, and Compensation practice had significant positive influence on employees’ satisfaction among Nigerians and Other Nationals in food and beverages MNCs in Nigeria (β = - .025 - .441 ; P< .000 ; β = - .025; P> .343); (β = - .124 -.514; P< .000): (β = .168 - .299; P< .000: β = -.15; P> .566; - .225 -.246; P< .000): (β = -.144 -.421; P< .000; β = -.004; P> .886): (β = -.105 - .456; P< .000 -.001) respectively, except for power distance that had negative and insignificant influence on employees’ satisfaction among Nigerians with respect to recruitment and selection and collectivity and individuality that had negative and insignificant influences on employees’ satisfaction among Nigerians with respect to compensation and employee empowerment.
Hot-spot identification on a broad class of proteins and RNA suggest unifying principles of molecular recognition

Chemically diverse fragments tend to collectively bind at localized sites on proteins, which is a cornerstone of fragment-based techniques. A central question is how general are these strategies for predicting a wide variety of molecular interactions such as small molecule-protein, protein-protein and protein-nucleic acid for both experimental and computational methods. To address this issue, we recently proposed three governing principles, (1) accurate prediction of fragment-macromolecule binding free energy, (2) accurate prediction of water-macromolecule binding free energy, and (3) locating sites on a macromolecule that have high affinity for a diversity of fragments and low affinity for water. To test the generality of these concepts we used the computational technique of Simulated Annealing of Chemical Potential to design one small fragment to break the RecA-RecA protein-protein interaction and three fragments that inhibit peptide-deformylase via water-mediated multi-body interactions. Experiments confirm the predictions that 6-hydroxydopamine potently inhibits RecA and that PDF inhibition quantitatively tracks the water-mediated binding predictions. Additionally, the principles correctly predict the essential bound waters in HIV Protease, the surprisingly extensive binding site of elastase, the pinpoint location of electron transfer in dihydrofolate reductase, the HIV TAT-TAR protein-RNA interactions, and the MDM2-MDM4 differential binding to p53. The experimental confirmations of highly non-obvious predictions combined with the precise characterization of a broad range of known phenomena lend strong support to the generality of fragment-based methods for characterizing molecular recognition.
A Survey on Industry 4.0 for the Oil and Gas Industry: Upstream Sector

The market volatility in the oil and gas (O&G) sector, the dwindling demand for oil due to the impact of COVID-19, and the push for alternative greener energy are driving the need for innovation and digitization in the O&G industry. This has attracted research interest from academia and the industry in the application of industry 4.0 (I4.0) technologies in the O&G sector. The application of some of these I4.0 technologies has been presented in the literature, but the domain still lacks a comprehensive survey of the application of I4.0 in the O&G upstream sector. This paper investigates the state-of-the-art efforts directed toward I4.0 technologies in the O&G upstream sector. To achieve this, first, an overview of the I4.0 is discussed followed by a systematic literature review from an integrative perspective for publications between 2012-2021 with 223 analyzed documents. The benefits and challenges of the adoption of I4.0 have been identified. Moreover, the paper adds value by proposing a framework for the implementation of I4.0 in the O&G upstream sector. Finally, future directions and research opportunities such as framework, edge computing, quantum computing, communication technologies, standardization, and innovative areas related to the implementation of I4.0 in the upstream sector are presented. The findings from this review show that I4.0 technologies are currently being explored and deployed for various aspects of the upstream sector. However, some of the I4.0 technologies like additive manufacturing and virtual reality are least explored.
STEM integrated education and multimodal educational material

The present article aims to underline the role of multimodal educational material in STEM Integrated early childhood education. Through social semiotics assumption that meaning arises in action and interaction, we argue that robotics, digital media, haptic materials, toys, books, tablets, actions, and artifacts have an active and dynamic role in multimodal learning and construct meaning in young children's STEM educational process. The literature review has revealed a research gap concerning combined multimodal aspects in STEM concepts for young children. We adopted a mixed-method collective case study design based on four case studies in which children interact with multimodal STEM educational material. Due to the principles for effective STEM teaching and the perspectives of integrated STEM education, our findings illustrate that MmEM in STEM concepts, through play-based, model-based, inquiry-based teaching practices (among other open-ended), may provide to children multimodal learning environments, engage them in authentic and meaningful learning, promote teamwork, communication and social skills, challenge and motivate them to make meaning of their learning.
Characterization of Atypical Pheochromocytomas with Correlative MRI and Planar/Hybrid Radionuclide Imaging: A Preliminary Study

Pheochromocytomas may show atypical imaging findings leading to diagnostic pitfalls. We correlated the results of magnetic resonance imaging (MRI) with those of radionuclide studies in patients with pheochromocytomas. T2-weighted (-w), T1-w chemical-shift and T1-w dynamic contrast enhanced (DCE) MRI sequences were evaluated to assess tumor structure. 131Iodine metaiodobenzylguanidine (MIBG) scintigraphy, 18fluoro (F) deoxyglucose (FDG) positron emission tomography/computed tomography (PET/CT) or FDG PET/MRI were evaluated for direct comparison. Of a total of 80 adrenal lesions in 73 patients, 20 in 18 patients were pheochromocytomas. More than half (55%) of the pheochromocytomas (n = 11) had the typical increased signal intensity on T2-w and T1-w DCE, while the remaining (n = 9) lesions showed atypical findings; of these nine latter atypical lesions, seven (35%) were cystic (two totally, three predominantly and two partially) and two (10%) were hemorrhagic on MRI. In these atypical lesions, MIBG scintigraphy (n = 5), FDG PET/CT (n = 6) or FDG PET/MRI (n = 2) showed inhomogeneous tracer uptake in the residual viable tissue providing tumor characterization; however, one predominantly cystic pheochromocytoma showed false negative MIBG scan. Our preliminary results show that cystic degeneration may be frequent in pheochromocytoma being so marked that only a thin rim of viable cells may residue to disclose the true nature of the tumor. MRI findings together with those of correlative planar/hybrid radionuclide images are helpful to characterize these atypical pheochromocytomas. In particular, tumor accumulation of MIBG and/or FDG is able to classify these lesions as not simple cysts; in detail, the presence of partial MIBG uptake allows the diagnosis of pheochromocytomas, while the presence of partial FDG uptake generically reflects the presence of viable solid tissue of such cystic tumors.
Workplace Incivility and Job Satisfaction: Mediation of Subjective Well-Being and Moderation of Forgiveness Climate in Health Care Sector

Our study investigates the role of subjective well-being and forgiveness climate between workplace incivility and job satisfaction. Drawing on conservation of resource theory, we proposed a model in which workplace incivility is associated with job satisfaction through subjective wellbeing, and forgiveness climate moderates this association. Data was collected through a survey method from 672 nurses and doctors in the health care sector at two different times. Respondents completed workplace incivility and subjective well-being scale at Time 1, and a forgiveness climate and job satisfaction scale at time 2. Findings through PROCESS Macros (Model 5) show that workplace incivility has a negative influence on job satisfaction and subjective well-being. Subjective well-being plays a mediating role in the negative effect of workplace incivility on job satisfaction. Moreover, forgiveness climate moderates the relationship between workplace incivility and job satisfaction. The implications for practice and research are discussed.
THE RELATIONSHIP BETWEEN L2 LISTENING AND METACOGNITIVE AWARENESS ACROSS LISTENING TESTS AND LEARNER SAMPLES

ABSTRACT To better understand the relationship between second-language (L2) listening comprehension and metacognitive awareness, we examined the moderating effects of listening tests and learner samples while focusing on aspects of metacognitive awareness. Students of English-as-a-foreign-language at a Japanese university (n = 75; the 2019 cohort) took the Test of English as a Foreign Language Institutional Testing Program (TOEFL ITP®) test, a paper-based TOEFL; the TOEFL Internet-based test (TOEFL iBT®); and the Metacognitive Awareness Listening Questionnaire (MALQ). Another group of students (n = 107; the 2020 cohort) took the TOEFL ITP and MALQ. Random forest analysis was applied to the results of the 2019 cohort, showing that, in order of importance, person knowledge, mental translation, and directed attention were related to listening comprehension in both listening tests. Problem solving was not related in either listening test. Further, planning and evaluation strategies were related to listening comprehension only in the TOEFL ITP. Comparison between the TOEFL ITP results of the 2019 and 2020 cohorts showed that only person knowledge was related to listening comprehension across the two cohorts, indicating a strong generalizability of person knowledge and weak generalizability of the remaining metacognitive strategies across learners. Implications and future directions are discussed.
Wastewater surveillance of SARS-CoV-2 corroborates heightened community infection during the initial peak of COVID-19 in Bexar County, Texas

ABSTRACT The purpose of this study was to conduct a preliminary assessment of the levels of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA in wastewater at the Salitrillo Wastewater Treatment Plant in Texas during the initial peak of coronavirus disease 2019 (COVID-19) outbreak. Raw wastewater influent (24 h composite, time-based 1 L samples, n = 13) was collected weekly during June–August 2020. We measured SARS-CoV-2 RNA in wastewater by reverse transcription droplet digital PCR using the same N1 and N2 primer sets as employed in COVID-19 clinical testing. Virus RNA copies for positive samples (77%) ranged from 1.4 × 102 to 4.1 × 104 copies per liter of wastewater, and exhibited both increasing and decreasing trends, which corresponded well with the COVID-19 weekly infection rate (N1: ρ = 0.558, P = 0.048; N2: ρ = 0.487, P = 0.092). A sharp increase in virus RNA concentrations was observed during July sampling dates, consistent with the highest number of COVID-19 cases reported. This could be attributed to an increase in the spread of COVID-19 infection due to the Fourth of July holiday week gatherings (outdoor gatherings were limited to 100 people during that time). Our data show that wastewater surveillance is an effective tool to determine trends in infectious disease prevalence, and provide complementary information to clinical testing.
Occult Nodal Metastasis Defined by PET-CT Identifies a Unique Clinical Subtype of Lung Cancer: A Retrospective Multicenter Study

PurposeTo investigate the surgical prognosis and efficacy of adjuvant therapy in non-small cell lung cancer (NSCLC) with occult lymph node metastasis (ONM) defined by positron emission tomography-computed tomography (PET-CT). MethodsA total of 3537 NSCLC patients receiving surgical resection were included in this study. The prognosis between patients with ONM and evident nodal metastasis, ONM patients with and without adjuvant therapy were compared, respectively.ResultsONM was associated with significantly better prognosis than evident nodal metastasis whether for patients with N1 (5-year OS: 56.8% versus 52.3%, adjusted p value=0.267; 5-year RFS: 44.7% versus 33.2%, adjusted p value=0.031) or N2 metastasis (5-year OS: 42.8% versus 32.3%, adjusted p value=0.010; 5-year RFS: 31.3% versus 21.6%, adjusted p value=0.025). In ONM population, patients receiving adjuvant therapy yielded better prognosis comparing to those without adjuvant therapy (5-year OS: 50.1% versus 33.5%, adjusted p value<0.001; 5-year RFS: 38.4% versus 22.1%, adjusted p value<0.001). Conclusions﻿ONM defined by PET-CT identifies a unique clinical subtype of lung cancer, ONM is a favorable prognostic factor whether for pathological N1 or N2 NSCLC and adjuvant therapy could provide additional survival benefits for ONM patients.
Geographical Distribution of Zebu Breeds in Brazil And Their Relationship With Environmental Variables and Human Development Indicator

The aim of this study was to evaluate the geographical distribution of zebu breeds in Brazil and correlate their occurrence with environmental variables and human development indicator. The herds of purebred zebu cattle in Brazil were classified as beef breeds (Brahman, Polled Brahman, Nelore, Polled Nelore and Tabapuã), dairy breeds (Gir and Polled Gir), and dual-purpose breeds (Guzerá, Indubrasil, Polled Indubrasil, Sindhi and Polled Sindhi), all breeds being spatialized in ArcGIS program. Variables examined included environmental and human development indicator. The statistical analysis included analysis and logistic regression.The lower distribution of zebu cattle in the states of Northeast compared to other locations is probably due to its extreme climate, highly susceptible to long periods of high temperatures and lower precipitation, which directly affects local livestock. The beef breeds were evenly spread throughout the country. The location occupied for beef breeds was influenced by environmental variables, showing a higher incidence with increased precipitation, normalized difference vegetation index (NDVI), temperature, relative humidity and temperature humidity index (THI), as well as establishments without family agriculture and rivers and streams with forest protection. The location used for dual-purpose and dairy breeds was influenced by areas with cultivated cutting forages, areas with integrated crop-livestock forest systems and areas with rotational grazing system, indicating a higher occupation in fertile lands. The Gir breed, the only one with dairy exploration in this study, showed herds in establishments with family agriculture, characterized by small to medium farms, and in regions with higher altitude.
Fracture Fixation Technique and Chewing Side Impact Jaw Mechanics in Mandible Fracture Repair

Lower jaw (mandible) fractures significantly impact patient health and well‐being due to pain and difficulty eating, but the best technique for repairing the most common subtype—angle fractures—and rehabilitating mastication is unknown. Our study is the first to use realistic in silico simulation of chewing to quantify the effects of Champy and biplanar techniques of angle fracture fixation. We show that more rigid, biplanar fixation results in lower strain magnitudes in the miniplates, the bone around the screws, and in the fracture zone, and that the mandibular strain regime approximates the unfractured condition. Importantly, the strain regime in the fracture zone is affected by chewing laterality, suggesting that both fixation type and the patient's post‐fixation masticatory pattern—ipsi‐ or contralateral to the fracture— impact the bone healing environment. Our study calls for further investigation of the impact of fixation technique on chewing behavior. Research that combines in vivo and in silico approaches can link jaw mechanics to bone healing and yield more definitive recommendations for fixation, hardware, and postoperative rehabilitation to improve outcomes. © 2021 The Authors. JBMR Plus published by Wiley Periodicals LLC on behalf of American Society for Bone and Mineral Research.
Framing Benefits in Decision Aids: Effects of Varying Contextualizing Statements on Decisions About Sacubitril-Valsartan for Heart Failure

Background. Presenting numeric data alone may result in patients underappreciating clinically significant benefits. Contextualizing statements to counter this may raise concern about absence of neutrality. These issues arose during construction of a decision aid for sacubitril-valsartan, a heart failure medication associated with a ∼3% absolute reduction in 2-year mortality that carries high out-of-pocket cost. A contextualizing statement framing this as a “pretty big benefit” was incorporated. The impact of statements like this within decision aids is unknown. Objective. This online Qualtrics survey sought to deepen understanding of benefit framing by testing the impact of varying contextualizing statements within a decision aid for sacubitril-valsartan. Design. Participants were randomly assigned to receive one of six abbreviated versions of a decision aid for sacubitril-valsartan that varied only by contextualizing statement (ranging from strongly neutral to strongly positive and using relative and absolute risk reductions). Participants were asked to answer questions regarding the likelihood of taking the medication at a cost of $50/month and their perception of the drug’s benefits. Results. A total of 1873 participants who were demographically similar to the heart failure population completed the survey. Fifty-four percent were willing to take sacubitril-valsartan at $50/month. Each of the five experimental contextualizing statements was compared with the baseline version; no significant differences were observed in reported likelihood of taking sacubitril-valsartan. After controlling for demographics and covariates, group assignment did not predict likelihood of taking the medication. Higher income, better self-reported health status, and younger age were associated with increased likelihood of taking sacubitril-valsartan. Limitations. This study used a hypothetical scenario and evaluated one method of delivering contextualizing statements. Conclusions. Contextualizing statements as tested within this decision aid did not affect decision making.