Miracle-dz/UniFAR-FTUs huggingface dataset:
First attempt to quantify W7-X island divertor plasma by local experiment-model comparison

As a complement to our recent work [], which focused on understanding the basic detachment physics and general experimental and numerical trends observed in the W7-X island divertor, this paper compares EMC3-Eirene simulation results with different local diagnostics, including IR cameras, Langmuir probes, Hα-cameras, and Thomson scattering. The main purposes are to (1) justify the simulation setup in the previous work, (2) identify the application limitations of the current EMC3-Eirene model, (3) verify the consistency of different diagnostics, and (4) isolate the main geometric and physical effects that need to be prioritized in further developing the EMC3-Eirene code and improving diagnostic capabilities. It turns out that the current version of the EMC3-Eirene code (without drifts) is not yet able to quantitatively reproduce all selected local measurements simultaneously under the current experimental conditions (in particular, the existence of error fields). Nevertheless, it can be shown that within a reasonable range of variation in magnetic configuration, cross-field transport, and SOL plasma state in the modeling, a region of overlap between the numerical results and the local measurements can be established. More accurate model-experiment comparisons will require clarification of error fields, implementation of drifts in EMC3, and improvement of diagnostic capabilities.
Determination of Esomeprazole by Complexation Method

Esomeprazole magnesium trihydrate is an effective proton pump inhibitor used for dyspepsia and peptic ulcer. In the present study and a simple, accurate and precise spectroscopic method has been developed for the estimation of esomeprazole in raw material and tablet dosage forms. The method involves complexation of esomeprazole in H2SO4 with iron(II) and 1,10-Phenanthroline and the colour developed was stabilized by using o-phosphoric acid. The coloured solution showed an absorption maximum of 507 nm. A calibration curve was plotted (0.5-4 μg/ml) and found a regression co efficient r2=0.9723. The limit of detection was found to be 0.522318 and limit of quantification was found to be 0.15833. A result of analysis obtained from the studies was validated statistically and by recovery studies. The methods showed good reproducibility and recovery with %RSD less than 1.
Interactive comment on “Numerical investigation on spectral geometries and their relation to non-Gaussianity in sea states with occurrence of rogue waves: wind-sea dominated events” by

In line 53-55, the authors say that “it remains difficult to assess directly the severity of the deviation from Gaussianity for a given sea state, or to infer the nature of the dominant nonlinearities. ” I didn’t figure out why the authors argued “it remains difficult”. I believe that the existing theories mentioned in line 51-53 can be applied to predict the non-Gaussianity for operational wave forecasts. Therefore, I cannot understand why HOSM was required to predict the kurtosis for the rogue wave events mentioned in the manuscript. Since the line 53-55 corresponds to the key issue of this manuscript, I think these lines should be written in more detail.
Personality Traits among Psychiatric Out-patients with Suicide Attempt Attending Tertiary Care Hospital in Eastern Nepal

Background-Suicide attempt is a self-injurious behaviour with a nonfatal outcome. Studies report increasing hospital admissions due to self-inflicted harm (SIH) as well as a higher likelihood of associated psychosocial factors in SIH cases. We conducted a study to explore personality traits, socio-demographic profiles and psychiatric disorders among the suicide attempt cases in a tertiary care hospital setting of eastern Nepal.Methods-It was a descriptive study conducted with purposive sampling in a tertiary care hospital among suicide attempt cases who visited to out-patient department of psychiatry. A total of 113 cases (calculated sample size) were enrolled after written informed consent within study period of 1 year. Personality traits were analyzed by using ‘Personality Trait Inventory’ questionnaire. Psychiatric diagnosis was made as per the ICD-10 diagnostic criteria. Demographic variables were recorded in a semi-structured proforma.Results-Majority of the subjects were female, married and literate, with the most common age group being 20–29 and < 20 years. Most of them were Hindu, from low socioeconomic status, joint family and cities, and were homemakers. Poisoning was the most common mode of suicide attempt and organo-phosphorous compounds the most common poison used. Some (13.3%) had past and 5.3% had family history of suicidal attempt. Most cases 63 (55.8%) were referred from Departments of Internal Medicine, followed by Emergency 28 (24.8%), self 18 (15.9%) and Paediatrics 4 (3.5%). The common ICD-10 psychiatric diagnoses were: Substance use disorder, main being alcohol (42%), Adjustment (34%) and mood disorders (22%). Emotional instability trait was the most common Personality Trait 70 (61.9%), followed by Depressive tendency 46 (40.7%). Personality disorder was present in 34%; most common being Emotionally unstable personality disorder.Conclusions-Emotional instability trait was found in the highest number of suicide attempt patients.
EFFICIENCY IN APPLICATION OF OIL ROYALTIES RESOURCES: IDENTIFICATION OF BENCHMARK BRAZILIAN MUNICIPALITIES

In a context that presents an opportunity for academic discussion on the quality of receipt of oil royalty revenues and the efficiency in the use of these resources, research aims to identify which municipalities receiving oil royalties can be considered as benchmark in the application of budgetary resources. The relevance of this study lies in the academic and political discussions on the subject generated from the discovery of large oil reserves in the Brazilian territory and the consequent changes in the legislation on the model of sharing these resources. The Data Envelopment Analysis instrument (CCR model) was used to verify the efficiency in the allocation of public resources in 115 municipalities located throughout the Brazilian territorial extension, considering as input variables “tax revenues” and “current transfer revenues”, and as a product-variable, the “Municipal Human Development Index”, which was preceded by a cluster analysis. Results indicated that more than 70% of the investigated municipalities have an efficiency score of less than 0.4, suggesting a marked difference between the results achieved by the benchmark municipalities and the other municipalities not located at the efficiency frontier. These results are consistent with previous studies, which indicate that the resources destined to minimize the effects of negative externalities from oil extraction activities may not be generating the desired results regarding the improvement in human development of its receptors.
Niosome Encapsulated Bromelain Reduced IL-6 and TNF-α in LPS Induced Human Skin Fibroblast Cell Line

The topical delivery of bromelain as an anti-inflammatory solution for skin inflammation has attracted the attention of researchers. Due to the skin barrier issue, a new method was designed for the effective delivery of specific doses of bromelain to the desired action sites. A niosome was selected as a novel and practical transdermal vehicle for the delivery of bromelain to inflamed sites. In this regard, a lipopolysaccharide (LPS)-induced human skin fibroblast (HSF1184) cell line was assembled in-vitro as a simulated model. The levels of interleukin-6 (IL-6) and tumour necrosis factor alpha (TNF-α), the two immune-modulatory regulators of cell responses to inflammation, were measured to determine the response towards the niosome-encapsulated bromelain treatment. The results showed that the niosome-encapsulated bromelain significantly reduced the levels of IL-6 and TNF-α compared to the non-encapsulated bromelain, the vehicle (niosome) and the control.
The High Intensity Proton Accelerator Facility

The High Intensity Proton Accelerator Facility at PSI routinely produces a proton beam with up to 1.4 MW power at a kinetic energy of 590 MeV. The beam is used to generate neutrons in spallation targets, and pions in meson production targets. The pions decay into muons and neutrinos. Pions and muons are used for condensed matter and particle physics research at the intensity frontier. This section presents the main physics and technology concepts utilized in the facility. It includes beam dynamics and the control of beam losses and activation, power conversion, efficiency aspects, and performance figures, including the availability of the facility.
Distance Preserving Graph Embedding

Today graph data structures are everywhere, be it social graphs describing the relation between diﬀerent accounts on social media platforms, road graphs describing the connections between diﬀerent intersections in a city, or network graphs describing the connections between diﬀerent servers. Being able to quickly query the shortest path distance between two nodes in such graphs can be of great use. However, using traditional graph traversing shortest path algorithms such as Di-jkstra [1] or Floyd-Warshall [2] is slow on big graphs, and alternatively storing all shortest path information for lookup takes too much space. Therefore, there have been various attempts at ﬁnding ways to speed up shortest path queries. Some of them include introducing shortcuts in the graph that preserve distance or computing labels for each node that encode the distance to selected landmark nodes. This paper explores other approaches that have not been explored in-depth yet. On the one hand, we investigate the distance preserving capabilities of established node embedding techniques using a simple multilayer perceptron. On the other hand, we propose our own graph neural network models for generating distance preserving embeddings and predicting shortest path distances. Furthermore, we investigate the relationships between certain parameters such as embedding size and prediction accuracy.
Using RFLP-PCR Technique in Determining Genotypes of Giardia lamblia from Diarrhea Cases in Children in AL-Diwaniyah City, Iraq

Introduction: Giardia lamblia is one of the most prevalent intestinal protozoa in the world, which affect children in both undeveloped and developing countries. This study aimed to determine genotypes of the Giardia lamblia using polymerase chain reaction (PCR) and restriction fragment length polymorphism (RFLP)-PCR techniques. Additionally, the relationship between genotype patterns and their geographical distribution, gender, and age was investigated. Methods: The current study included 926 samples of faeces of children suffering from diarrhoea, who visits the internal clinics at Teaching Hospital, and Child Hospital in AL- Diwaniyah City from November 2012 - Jun 2013. For age groups of 1-12 years exclusively. The samples were examined using a direct mount wet smear, The positive samples were preserved without adding preservatives at a temperature of -20°C until the DNA extraction for G. lamblia genotyping by using PCR and RFLP-PCR technique. Results: Giardia lamblia was detected in 2.15% (20/926) of samples from diarrhea cases in children by amplification of glutamate dehydrogenase gene (gdh) using two specific primers GDHiR and GDHiF. It was revealed that 7 samples belonged to genotype A (35%) and 13 samples belonged to genotype B (65%). All genotype A samples belonged to subgenotype AII (100%), while genotype B samples belonged to subgenotypes BIII (53.61 %) and BIV (47.38 %). Genotype A was detected in children of 1-6 years of age while B genotype was detected in all age groups. Both of the genotypes have been detected in both genders (male and female) and genotype B was found in both urban and rural areas; however, its prevalence was higher in rural areas than in urban areas (100% and 30%, respectively). Conclusion: There are two genotypes of Giardia lamblia, genotype A and genotype B, each of which has secondary genetic patterns which include AII, BIII, and BIV.
Proof of Polignac's conjecture for gap equal to eight

In this paper proof of the Polignac's Conjecture for gap equal to eight is going to be presented. It will be shown that consecutive primes with gap eight could be obtained through two stage sieve process, and that will be used to prove that infinitely many primes with gap eight exist. The proof represents an simple extension of the recently presented proof that infinitely many sexy prime exist. The major contribution of this paper is presentation of all elementary modules that are necessary for the proof of Polgnac's conjecture in general case.
DMSO_A_237700 1203..1214

1Lee’s Endocrinology Clinic, Pingtung 90000, Taiwan; 2Division of Cardiology, Department of Internal Medicine, E-Da Hospital, Kaohsiung 82445, Taiwan; 3School of Medicine for International Students, College of Medicine, I-Shou University, Kaohsiung 82445, Taiwan; 4The School of Chinese Medicine for Post Baccalaureate, College of Medicine, I-Shou University, Kaohsiung 82445, Taiwan; 5Division of Endocrinology andMetabolism, Department of Internal Medicine, E-Da Hospital, Kaohsiung 82445, Taiwan; 6Division of Cardiology, Department of Internal Medicine, E-Da Cancer Hospital, Kaohsiung 82445, Taiwan; 7Division of Gastroenterology and Hepatology, Department of Internal Medicine, E-Da Hospital, Kaohsiung 82445, Taiwan; 8Health Examination Center, E-Da Dachang Hospital, Kaohsiung 80794, Taiwan Purpose: This study aimed to investigate the common and unique risk factors and bidirec-
Urinary Bladder Calculus in an Adult Male Patient Presenting With Obstructive Features: The Radiologic Findings and a Case Report

Urinary lithiasis is a very common urological disease but bladder lithiasis is very uncommon and account for about 5% of urolithiasis and most frequent urolithiasis in pediatric age. It is very important to exclude lower urinary tract obstruction as the cause, but significant cases may come without obstruction. The male sex is more affected than the female sex. This is a case of a 65-year-old male patient with complaint of suprapubic pain, dysuria and increased frequency of micturition for more than two years prior to presentation. Abdominopelvic ultrasound demonstrated a continuous bicovex-shaped echogenicity casting posterior acoustic shadow masking the posterior bladder wall posteriorly in keeping with a bladder calculus. There is associated moderate hydroureteronephrosis with enlargement of the kidneys bilaterally. The plain abdominopelvic radiograph demonstrated a dumb-bell shaped radio-opacity of calcific density in the pelvic cavity in keeping with a bladder calculus The patient had extraperitoneal cystolithotomy with extraction of the entire calculus and got better. We present a case of an obstructive calculus in a 65-year-old male patient without an obvious infravesical urinary obstruction due to its rare nature and peculiar presentation.
Raising the bar to ultradisciplinary collaborations in management of chronic thromboembolic pulmonary hypertension

Chronic thromboembolic pulmonary hypertension is an underdiagnosed and potentially fatal subgroup of pulmonary hypertension, if left untreated. Clinical signs include exertional dyspnea and non-specific symptoms. Diagnosis requires multimodality imaging and heart catheterization. Pulmonary endarterectomy, an open heart surgery, is the gold standard treatment of choice in selected patients in specialized centers. Targeted medical therapy and balloon pulmonary angioplasty can be effective in high-risk patients with significant comorbidities, distal pulmonary vascular obstructions, or recurrent/persistent pulmonary hypertension after pulmonary endarterectomy. Currently, there is a limited number of data regarding novel coronavirus-2019 infection in patients with chronic thromboembolic pulmonary hypertension and the changing spectrum of the disease during the pandemic. Challenging times during this outbreak due to healthcare crisis and relatively higher case-fatality rates require convergence; that is an ultradisciplinary collaboration, which crosses disciplinary and sectorial boundaries to develop integrated knowledge and new paradigms. Management strategies for the "new normal" such as virtual care, preparedness for further threats, redesigned standards and working conditions, reevaluation of specific recommendations, and online collaborations for optimal decisions for chronic thromboembolic pulmonary hypertension patients may change the poor outcomes.
Evaluating methods for debris-flow prediction based on rainfall in an Alpine catchment

Abstract. The prediction of debris flows is relevant because this type of natural hazard can pose a threat to humans and infrastructure. Debris-flow (and landslide) early warning systems often rely on rainfall intensity–duration (ID) thresholds. Multiple competing methods exist for the determination of such ID thresholds but have not been objectively and thoroughly compared at multiple scales, and a validation and uncertainty assessment is often missing in their formulation. As a consequence, updating, interpreting, generalizing and comparing rainfall thresholds is challenging. Using a 17-year record of rainfall and 67 debris flows in a Swiss Alpine catchment (Illgraben), we determined ID thresholds and associated uncertainties as a function of record duration. Furthermore, we compared two methods for rainfall definition based on linear regression and/or true-skill-statistic maximization. The main difference between these approaches and the well-known frequentist method is that non-triggering rainfall events were also considered for obtaining ID-threshold parameters. Depending on the method applied, the ID-threshold parameters and their uncertainties differed significantly. We found that 25 debris flows are sufficient to constrain uncertainties in ID-threshold parameters to ±30 % for our study site. We further demonstrated the change in predictive performance of the two methods if a regional landslide data set with a regional rainfall product was used instead of a local one with local rainfall measurements. Hence, an important finding is that the ideal method for ID-threshold determination depends on the available landslide and rainfall data sets. Furthermore, for the local data set we tested if the ID-threshold performance can be increased by considering other rainfall properties (e.g. antecedent rainfall, maximum intensity) in a multivariate statistical learning algorithm based on decision trees (random forest). The highest predictive power was reached when the peak 30 min rainfall intensity was added to the ID variables, while no improvement was achieved by considering antecedent rainfall for debris-flow predictions in Illgraben. Although the increase in predictive performance with the random forest model over the classical ID threshold was small, such a framework could be valuable for future studies if more predictors are available from measured or modelled data.
One Size Does Not Fit All in Resource-Constrained ASR

The application of deep neural networks to the task of acoustic modeling for automatic speech recognition has resulted in dramatic decreases in ASR word error rates, enabling the use of this technology for interacting with smart phones and personal home assistants in high-resource languages. Developing ASR models of this caliber, however, requires hundreds or thousands of hours of transcribed speech recordings, which presents challenges for the vast majority of the world’s languages. In this paper, we investigate the utility of three distinct architectures that have previously been used for ASR in languages with limited training resources. We train and test these systems on publicly available ASR datasets for several typologically and orthographi-cally diverse languages, which were produced under a variety of conditions using different speech collection strategies, practices, and equipment. Although these corpora are comparable in size, we ﬁnd that no single ASR architecture outperforms all others. In addition, word error rates vary signiﬁcantly, in some cases within the range of those typically reported for high-resource languages. Our results point to the importance of considering language-speciﬁc and corpus-speciﬁc factors and experimenting with multiple approaches when developing ASR systems for languages with limited training resources.
Comparison between ultrasound guided regional anaesthesia and general anaesthesia in arteriovenous fistula creation at the Douala General Hospital

Department of Surgery and Specialities, Faculty of Medicine and Pharmaceutical Sciences, University of Douala, Douala, Cameroon. Department of Emergency Medicine Anaesthesiology and Critical Care, Douala General Hospital, Douala Cameroon. Department of Clinical Sciences, Faculty of Medicine and Pharmaceutical Sciences, the University of Douala, Douala, Cameroon. Department of Internal Medicine, Faculty of Medicine, Douala General Hospital, Douala, Cameroon. Department of Surgery, Faculty of Medicine, Douala General Hospital, Douala Cameroon. Department of Nephrology, Faculty of Medicine, Deaconess Hospital, Evansville, Indiana, USA.
The Effect of Pre-Operative Oral Carbohydrate Loading On Inflammatory Markers in Patients, With Advanced Stage Ovarian Cancer Undergoing Surgery: Randomised Control Trial

Objective: Historically, patients have fasted before elective surgery to ensure an empty stomach to avoid aspiration. However, fasting-induced biological changes may adversely affect the speed of recovery after surgery. In our randomised control trial, we tested the effect of oral carbohydrate loading on the inflammatory markers in patients undergoing major surgery for advanced stage ovarian cancer. Methods: A double-blinded, single-centre randomised trial was designed to recruit 110 patients with advanced stage epithelial ovarian cancer undergoing either primary surgery, or neoadjuvant chemotherapy prior to debulking surgery (IDS) (reference number: 08/H1306/108). Following informed consent, the patients were randomised into two groups. Group 1 received the carbohydrate drink and group 2 received flavoured water. The volume of fluid in both groups was 800ml the night before the surgery and 400ml two hours before the induction of anaesthesia. We examined the white cell, neutrophil and lymphocyte counts as well as lymphocyte subsets using a flowcytometry approach. Results: Between March 2009 and December 2011, 85 patients were approached, 80 patients were randomised and 75 completed the study. A decision was made to close the trial early, as a change in routine clinical practice meant that patients were admitted on the day of surgery rather than a day before. Analysis of the data revealed that oral carbohydrate loading can positively modulate the white cell counts in patients undergoing primary surgery rather than IDS. Conclusion: In this single-centre study, that failed to recruit the planned number of patients, we found evidence to support that oral carbohydrate intake pre-operatively has some positive influence in enhancing white cell counts in patients with advanced stage ovarian cancer having interval debulking surgery.
Egyptian Journal of Aquatic Biology & Fisheries

INTRODUCTION In contaminated aquatic environments several toxic metals occur, often creating undesirable living conditions for many plants and animals (Divya et al., 2012). Among animal species, fishes are the inhabitants that cannot escape from the detrimental effects of heavy metals (Olaifa et al., 2004). One category of toxic contaminations accumulated by fishes is heavy metals such as lead (Pb), mercury (Hg), cadmium (Cd), chromium (Cr) and arsenic (As). Any of these heavy metals can destroy life when they concentrate in the ARTICLE INFO ABSTRACT Article History: Received: Feb. 8, 2020 Accepted: March 22, 2020 Online: March 28, 2020 _______________