Miracle-dz/UniFAR-FTUs huggingface dataset:
Kemampuan Penalaran Matematis Ditinjau dari Kemampuan Pemecahan Masalah

Tujuan penelitian ini untuk mendeskripsikan pelaksanaan pembelajaran matematika dan mendeskripsikan klasifikasi kemampuan penalaran matematis ditinjau dari kemampuan pemecahan masalah siswa. Penelitian ini menggunakan metode penelitian kualitatif deskriptif. Teknik pengumpulan data yang dilakukan dalam penelitian ini yaitu melalui tes, observasi, wawancara, angket, dan dokumentasi. Hasil penelitian yang diperoleh dari pembelajaran matematika termasuk dalam kategori baik dengan presentase 78%, sedangkan data klasifikasi penalaran matematika didapatkan presentase sebesar 70% pada aspek memahami pengertian dalam kategori tinggi, aspek berpikir logis termasuk dalam kategori tinggi dengan presentase 53,3%, aspek memahami contoh negatif termasuk dalam kategori sangat tinggi dengan presentase 76,7%, aspek berpikir sistematis dan menentukan strategi termasuk dalam kategori tinggi dengan presentase 73,3%, berpikir konsisten termasuk dalam kategori tinggi dengan presentase 66,7%, aspek membuat alasan termasuk dalam kategori rendah dengan presentase 33,3%, aspek berpikir deduksi termasuk dalam kategori rendah dengan presentase 36,7%, aspek menentukan metode termasuk dalam kategori sangat tinggi dengan presentase 80%, sedangkan pada aspek menarik kesimpulan termasuk dalam kategori tinggi dengan presentase 60%. Secara keseluruhan didapatkan hasil presentase sebesar 62,3% teramasuk dalam kategori tinggi
Engineering modification of genome-reduced strain Bacillus amyloliquefaciens for enhancing surfactin production

Background: Genome reduction and metabolic engineering have emerged as intensive research hotspots for constructing the promising functional chassis and various microbial cell factories. Surfactin, a lipopeptide-type biosurfactant with broad spectrum antibiotic activity, has wide application prospects in anticancer therapy, biocontrol and bioremediation. Bacillus amyloliquefaciens LL3, previously isolated by our lab, contains an intact srfA operon in the genome for surfactin biosynthesis.Results: In this study, a genome-reduced strain GR167 lacking ~4.18% of the B. amyloliquefaciens LL3 genome was constructed by deleting some unnecessary genomic regions. Compared with the strain NK-1 (LL3 derivative, ΔuppΔpMC1), GR167 harbored faster growth rate, higher transformation efficiency, increased intracellular reducing power level and higher heterologous protein expression capacity. Furthermore, the chassis cell GR167 was engineered for enhanced surfactin production. Firstly, the iturin and fengycin biosynthetic gene clusters were deleted from GR167 to generate GR167ID. Subsequently, two promoters PRsuc and PRtpxi from LL3 were obtained by RNA-seq and promoter strength characterization, and then they were individually substituted for the native srfA promoter in GR167ID to generate GR167IDS and GR167IDT. The best mutant GR167IDS showed a 678-fold improvement in the transcriptional level of the srfA operon relative to GR167ID, and it produced 311.35 mg/L surfactin, with a 10.4-fold increase relative to GR167.Conclusions: The genome-reduced strain GR167 was advantageous over the parental strain in several industrially relevant physiological traits assessed and it was highlighted as a chassis cell for further genetic modification. In future studies, further reduction of the LL3 genome can be expected to create high-performance chassis for synthetic biology applications.
Analyzing the value of NUSAP1 in hepatocellular carcinoma from clinical and molecular mechanism perspectives: Bioinformatics-based approach.

Background: Hepatocellular carcinoma (HCC) is one of the most common and highest mortality rates carcinomas worldwide. At present, there are varies of therapeutic methods can be provided for HCC patients. However, there is no one method can inhibit occurrence and development of HCC very well, and prognosis of HCC patients is still very poor. Herein, our study aims to identify a key gene closely related to occurrence, development, poor prognosis of HCC and explore its underlying mechanism from molecular level.Methods: GSE62232, GSE102079, GSE112790 and GSE121248 genes expression profile datasets were screened from Gene Expression Omnibus (GEO) database. R studio was used to identify DEGs of each dataset. Venn online tool was used to generate a Venn diagram and screen overlapping DEGs of the four datasets. Search Tool for the Retrieval of Interacting Genes (String) online tool was used to draw Protein–Protein Interaction (PPI) network. And the most significant module and the key gene NUSAP1 in PPI network were identified by MCODE and cytoHubba plug-in in Cytoscape software. Oncomine database and Kaplan–Meier Plotter database were used to analyze relationships between expression of NUSAP1 and occurrence, development, prognosis of HCC. The cBioPortal online tool was used to identify co-expression genes of NUSAP1 in HCC patients from TCGA database. Then, KEGG pathway analysis was carried out by DAVID online tool and Cell cycle pathway map was generated by Kyoto Encyclopedia of Genes and Genomes (KEGG) online tool.Results: A total of 86 overlapping DEGs were screened, which included 55 up-regulated DEGs and 31 down-regulated DEGs. Then the key gene NUSAP1 in the PPI network were screened using cytoHubba plug-in in Cytoscape software. We found NUSAP1 may be associated with occurrence, development and poor prognosis of HCC by analyzing HCC patients in Oncomine database and Kaplan–Meier Plotter. Co-expression genes of NUSAP1 in TCGA database were obtained by cBioPortal. And KEGG pathway analysis was produced using the top 300 co-expression genes of NUSAP1, the result showed most co-expression genes closely related to the expression of NUSAP1 were concentrated in Cell cycle. Thus, we generate a KEGG pathway map of Cell cycle and found that most of these genes were located in S phase and G2/M phase of the Cell cycle and they could regulate the genes in G1 phase, hence, we inferred that NUSAP1 may regulate the progression of HCC by promoting the transition from the G1 phase to the S phase.Conclusion: NUSAP1 may influence occurrence, development and prognosis of HCC and might be a new molecular marker in HCC.
PENGARUH PENAMBAHAN AMPAS KELAPA DAN KULIT PISANG TERHADAP PRODUKSI BIOGAS DARI KOTORAN SAPI

Abstrak Bahasa Indonesia Biogas merupakan sebuah energi terbarukan atau energi alternatif yang memanfaatkan proses pembusukan dari berbagai macam limbah organik yang dapat menghasilkan gas metana (CH4). Tujuan penelitian ini adalah untuk mengetahui komposisi substrat yang optimum dan pengaruh penambahan ampas kelapa dan kulit pisang terhadap produksi biogas dari kotoran sapi. Parameter yang diamati meliputi: karakteristik bahan, derajat keasaman (pH), temperatur, produksi dan produktivitas biogas serta karakteristik nyala dari biogas. Penelitian ini diharapkan dapat menghasilkan teknologi tepat guna untuk mengolah limbah ampas kelapa dan kulit pisang menjadi produk yang bernilai tambah dan informasi ilmiah tentang pengaruh penambahan ampas kelapa dan kulit pisang terhadap biogas. Penelitian menggunakan rancangan acak lengkap dengan 6 perlakuan perbandingan komposisi berturut-turut kotoran sapi : kulit pisang : ampas kelapa yakni A 50:40:10, B 50:30:20, C 50:20:30, D 50:10:40, E 50:0:50, dan F 50:50:0 dengan masing-masing 3 kali ulangan. Data dianalisis menggunakan ANOVA dilanjutkan dengan uji Duncan. Hasil penelitian menunjukkan bahwa penambahan ampas kelapa dalam berpengaruh terhadap pH, C/N rasio, dan produksi biogas kumulatif; tetapi tidak berpengaruh terhadap temperatur, dan produktivitas biogas. Semakin banyak penambahan ampas kelapa maka semakin turun pH substrat, C/N rasio, dan produksi biogas. Kondisi optimum ada pada perlakuan F dengan komposisi 50:50:0 tanpa penambahan ampas kelapa dengan C/N rasio 21,22 dan pH 5,5-6,5. Abstract Bahsasa Inggris Biogas is a renewable or alternative energy utilizing the decomposition process of a wide range of organic wastes that generates methane gas (CH4). The purpose of this study the effect of the addition of coconut pulp and banana peels on biogas yield from cow dung. Parameters to be observed include: characteristics of substrates, degree of acidity (pH), temperature, biogas production and biogas yield, as well as the flame from biogas burning. This research is expected to produce appropriate technology for treating waste of coconut pulp and banana peels into value added products and scientific information on the effect of the addition of coconut pulp and banana peels to biogas. The experiment design was a completely randomized design of six treatments consecutive composition of cow dung : banana peel : coconut pulp namely A 50:40:10, B 50:30:20, C 50:20:30, D 50:10:40, E 50:0:50, and F 50:50:0 with 3 repetitions. The data were analyzed by ANOVA followed by Duncan test. The results showed that the addition of coconut pulp in the biogas composition affected on pH, C/N ratio, and biogas production, but had no effect on the temperature, and biogas yield. The increase in coconut pulp resulted in lower pH, and the C/N ratio lower, and lower biogas production. The optimum conditions for treatment with composition of 50:50:0 without the addition of coconut pulp with a C/N ratio of 21,22 and pH of 5,5-6,5.
Occurrence and characterization of Trichomitus batrachorum (Protista, Trichomonadidae) from Rhinella marina (Amphibia, Bufonidae) in the Philippines

Trichomonad isolation from amphibians is new in the Philippines as trichomonad studies in the country are few, limited only to mammals, reptiles and birds. Moreover, there are very few studies on amphibian-associated trichomonad ultrastructure and morphology. Trichomitus batrachorum (Ts. batrachorum) was isolated from Rhinella marina fecal samples and identified using SEM and TEM for ultrastructural study and 18S rRNA gene sequencing. A 37.5% prevalence of Ts. batrachorum from R. marina was observed based on in vitro culture and molecular analysis. Characteristics of this coprozoic trichomonad that provided distinctive features for classification included body size and shape, three anterior flagella and a recurrent flagellum, lamelliform undulating membrane, type A costa periodicity, V-shaped parabasal body, well-developed pelta, shape and location of organelles such as the nucleus, blepharoplast, axostyle, comb-like organelle, hydrogenosomes and the observation of a pseudocyst stage. DNA sequence analysis corroborated these results, and generated phylogenetic trees with high bootstrap support further proved the identity of the isolate. The few identified trichomonads in the Philippines exhibit the capability for adaptation to new hosts and it is possible they have zoonotic potential. These findings contribute to the existing trichomonad data sets in the country. This is the first ultrastructural study of Ts. batrachorum species isolated from a toad.
Smooth muscle Rac1 contributes to pulmonary hypertension

Pulmonary hypertension (PH) is a multifactorial chronic disease characterized by an increase in pulmonary artery (PA) resistance leading to right ventricle (RV) failure. Endothelial dysfunction and alteration of NO/cGMP signalling in PA plays a major role in PH. We recently described the involvement of the Rho protein Rac1 in the control of systemic blood pressure through its involvement in NO‐mediated relaxation of arterial smooth muscle cell (SMC). The aim of this study was to analyse the role of SMC Rac1 in PH.
Think-aloud usability testing of an app to increase physical activity

Background Insufficient physical activity is one of the most important risk factors for non-communicable diseases and should therefore be intensively prevented in all age groups. According to several trials, activity can be effectively increased by smartphone-based interventions. However, the use of digital applications depends on many factors such as user acceptance and intuitive operability. Therefore, usability testing has proven to be important for the successful development of digital interventions. Thus, the German app “VIDEA bewegt” was tested for its usability in order to assess strengths and weaknesses and to improve the app. Methods In April 2019, ten interviews were conducted using the think-aloud method and following a standardised protocol. The adult participants were confronted with “VIDEA bewegt” for the first time and had to perform pre-defined tasks covering the main features of the app. Demographics of the participants and their expectations towards the app were collected. The interviews were recorded and transcribed. The analysis of the transcripts was performed independently by two team members following the deductive qualitative content analysis according to Mayring. Results The app was rated positively in terms of design, basic registration process and the largely self-explanatory navigation. Users missed an explanation of the basic structure and included components of the programme. Several usability problems were described, including technical errors and problems with understanding individual control elements. Four of ten participants could imagine using the app in the future. Conclusions All test participants were able to use the app independently to a large extent and most of the a priori defined goals were achieved successfully. With certain minor changes, the usability can therefore be assessed as good. Trial registration The performed usability test is the basis of a study named “Evaluation of an app-based activity intervention for statutory health insured people” which is registered in the German Clinical Trials Register (DRKS). DRKS-ID: DRKS00017392 (14 June 2019)
Model Grouping in a Mixed-model Assembly Line

This paper investigates the problems of grouping N products on an assembly line with an objective of maximizing the option grouping rate. Before developing a mixed model grouping algorithm, simulation studies are committed for developing operating rules and evaluating the layout production systems. A mixed model grouping algorithm is suggested and it is applied to the color selection lane in automobile production system, which reveals a high mixed model grouping rate.
Paper title: Fast and Furious 3: illegal street racing, sensation seeking and risky driving behaviours in New Zealand

words): Illegal street racing is receiving increased media attention but there is little research in Australia and New Zealand to guide creative responses to this socially problematic behaviour. The paper investigates the relationship between interest in motor sport, illegal street racing and other risky driving behaviours amongst a sample of young male drivers in Christchurch. The study obtained questionnaire data from students in late high school, polytechnic college and university. The measured variables included a driving violations scale, attitudes to speeding, sensation seeking propensity, level of interest in motor sport and participation in illegal street racing. The results indicate that experience with motor sport was a significant factor in the explanation of both risky driving behaviour and the level of involvement in illegal street racing, taking into account the influence of sensation seeking. However, the way in which motor sport was linked with risky driving was different from the way it was linked with illegal street racing. Motor sport had a more direct influence on street racing, but influenced risky driving behaviour through the influence on attitude to speeding. The street racing group is characterised by high levels of sensation seeking and high levels of involvement in motor sport.
Capacity Estimation on Turboroundabouts with Gap Acceptance and Flow Level Methods

In the literature, linear models and exponential models based on gap acceptance theory are distinguished. Parameters for the linear models can be estimated only at the level of traffic flow, whereas the gap acceptance theory assumes that behavioral parameters (critical gap, follow-on time, and minimum headway) can be estimated at the vehicle level, and then capacity can be determined. However, in the latter method, measurements must also be made under saturated conditions because of so-called pseudoconflict (caused by vehicles leaving the roundabout in the opposite leg direction). An analysis of data sources (vehicle level and traffic flow level) indicates that the parameters estimated at the vehicle level correspond with those estimated at the level of traffic flow for single-lane roundabouts, but not for more complex situations. Despite this deficiency, better results can be gained with a model based on the present gap acceptance theory than with a linear model, provided that the parameters are adjusted to consider traffic flow measurements under saturated conditions. Additional research will be necessary to determine which underlying assumptions of the gap acceptance models cause these deficiencies. In Germany, capacity is higher in turboroundabouts than in compact two-lane roundabouts because of better use of the inner lane in the turboroundabout.
Environmental and organisational drivers for the nature of the relationship between illegal miners and mining companies

Artisanal and/or illegal mining occurs throughout the African continent and is affected by government institutions and their policies, mining companies and their activities as well as the communities where it occurs. Mining companies, in particular, make significant investments in the communities around their mines via corporate social responsibility (CSR). Mining companies choose to either acknowledge that illegal miners are in fact a stakeholder in the community around the mine, and manage the relationship proactively, or they choose to accept that the activity is illegal and/or opt for the government and police to get involved in managing the relationship. The research explores the possibility of mining companies and illegal miners cooperating with each other, instead of competing, and the nature of the mining companies CSR and stakeholder engagement (SE) strategies that make for a more transformational relationship. The research establishes the environmental and organisational factors that drive this relationship. Ten interviews were conducted with CSR practitioners, sustainability managers, asset protection experts, consultants and geologists working for gold mining companies operating throughout Africa. Qualitative data was collected through the use of semistructured interviews and the data was analysed using content analysis. Through this research, a stakeholder identification and engagement tool has been developed for mining companies and their managers to use throughout their global operations. This tool can be used to report and manage the relationship with illegal miners globally, as the relationship is highly dependent on the country setting and context. © 2014 University of Pretoria. All rights reserved. The copyright in this work vests in the University of Pretoria.
Comparison of the results of targeted temperature management of patients after sudden out-of-hospital cardiac arrest in intensive care units and intensive cardiac care units.

BACKGROUND Targeted temperature management (TTM) procedure is used to treat patients after sudden out-of-hospital cardiac arrest (OHCA). AIMS The aim of the analysis was to compare the results of TTM between cardiological (ICCU) and anesthesiological (ICU) departments. METHODS The Polish Registry of Therapeutic Hypothermia gathered data on 377 OHCA patients from 26 centers (257 and 120 patients were treated in the ICCU and ICU, respectively). Qualification for the TTM was based on the current inclusion criteria for the therapy. Analysed data included medical history and data on TTM and additional treatment. Main outcomes were in-hospital survival and complications, as well as neurological assessment using Glasgow Coma Scale (GCS) and 6-point Rankin scale. RESULTS Both ICU and ICCU patients were mostly males, with a mean age of 60 years. There were no significant differences regarding the medical history, mechanism of arrhythmia responsible for OHCA, GCS on admission, times of cardiopulmonary resuscitation activities and the times to the target temperature (33°C). The ICCU patients more likely had coronary angiography, dual antiplatelet therapy, intra-aortic balloon pump, intravascular hypothermia, dopamine and dobutamine, while the ICU patients norepinephrine. Pneumonia and acute renal failure occurred more frequently in the ICCU group. Death occurred in 17% and 20% of the ICU and ICCU patients (p=0.57), respectively. Rankin scale after 48 hours from the moment of discontinuation of sedation and at discharge were comparable for both groups. CONCLUSIONS ICCU become a considerable alternative to ICU to treat OHCA patients with the TTM.
SC Connect: Secure Server Access from Mobile Device

With the rise of technology, Server requirements have grown at an overwhelming pace. Accessing these servers and performing administrative tasks on them remotely has always been a great challenge. A popular utility used for this is the Secure Shell (SSH) which is being used extensively to get shell access on servers. SSH is however prone to vulnerabilities like Dictionary Attacks and Man-In-The-Middle (MITM) attacks. Further on, accessing servers from mobile devices is not yet feasible, SSH remains the de facto choice for it however SSH via third-party applications from mobile devices poses a security risk. In this paper, I've proposed an alternative system for accessing servers from mobile devices from operating systems Android and iOS. The main idea here is to keep commands pre-defined on servers and facilitate their execution from mobile applications securely.