Miracle-dz/UniFAR-FTUs huggingface dataset:
Microsatellite-Based Genotyping, Analysis of Population Structure, Presence of Trichomonas vaginalis Virus (TVV) and Mycoplasma hominis in T. vaginalis Isolates from Southwest of Turkey

Background: The present study aimed to determine genetic diversity of Trichomonas vaginalis (T. vaginalis) isolates with microsatellite markers in Turkey (Nov 2015 to 2016) and to create a web-based microsatellite typing (MT) approach for the global interpretation of the data. In addition, the endosymbiosis of Mycoplasma hominis (M. hominis) and T. vaginalis virus (TVV) in the isolates was also examined. Methods: The allele sizes for each locus were calculated and microsatellite types were determined according to the allele profiles. The population structure was examined with Bayesian clustering method. A website (http://mttype.adu.edu.tr) was created for collection and sharing of microsatellite data. Presence of TVV and M. hominis in T. vaginalis isolates were investigated with electrophoresis and PCR. Results: Of 630 vaginal samples T. vaginalis was detected in 30 (4.7%) and those were used for further analysis. The structure produced by a clustering algorithm revealed eight genetic groups. The typing of isolates according to microsatellites revealed 23 different microsatellite types. Three clones were determined among isolates (MT10 16.7%; MT18 10% and MT3 6.7%). The frequency of TVV and M. hominis was 16.6% (n=5) and 20% (n=6), respectively. Conclusion: Presence of three clones among 30 T. vaginalis isolates indicated that microsatellite-based genotyping was efficient to determine the clonal distribution of T. vaginalis isolates. Therefore, a promising tool might be developed further and adapted to the studies dealing with molecular epidemiology of T. vaginalis. Microsatellite data from forthcoming studies will be deposited and presented on the website. In addition, we also presented the frequency of two endosymbionts in T. vaginalis isolates for the first time in Turkey.
Effectiveness of The Coastal Tourist Nursing Model to Improve Balawista Behaviour in Bali Province

Introduction: Indonesia is an archipelagic country which is surrounded by coasts with great potential to develop the existing tourism sector. Objective: The aim of this research is to improve the coastal tourist nursing model to improve the behaviour of the Balawista (the coastal rescuer team). The coastal tourist nursing model is a part of community nursing. Method: The design of this research is operational research with three phaseswhich are phase I problem identification, phase II model and module development andphase III the coastal tourist nursing model trial through the establishment of a coastal health post by using quantitative quasi experimental research post-test with the control group, with a cluster sampling technique.The coastal tourist nursing model was carried out on the coast of Central Kuta sub-district, Badung Regency in 118 Balawistas. The statistical test used was chi square, t-test, multiple linear regression test and General linier Model Repeated Measure (GLM-RM). Results: The results obtainedwere that the coastal tourist nursing model wasproven to affect the Balawista’sbehaviour. Therefore this model can be used as one of the health efforts based on the communitywithin the coastal community in Indonesia.
Raman spectroscopy of 2‐hydroxyethyl methacrylate‐acrylamide copolymer using gamma irradiation for cross‐linking

A copolymer hydrogel was made by mixing acrylamide and 2-hydroxyethyl methacrylate monomers in water and polymerizing with gamma irradiation. The progress of polymerization and the vibrational structure of the hydrogel were examined using Raman spectroscopy. Raman spectra indicated that the copolymer has a molecular structure different from polyacrylamide or the individual monomers. The Raman data also indicate the presence of cross-linking at the CO, NH2, and OH side chains. The spectra further suggest the continuous lengthening of the backbone of the polymers with increasing gamma dose. This is shown as the increase in CC modes as CC vibrations decrease. Raman spectra changed most dramatically as the monomer mixture became a gel at a dose of approximately 320 Gy. Spectral differences were subtler with doses exceeding 640 Gy, although chain lengthening continued beyond 1500 Gy. Potential applications of the copolymer hydrogel include reconstructive tissue as well as a standard material for radiation protection dosimetry. Results are discussed in relation to other potential applications of this polymer and dose-dependent changes in the Raman spectrum. Copyright © 2006 John Wiley & Sons, Ltd.
Low-Intensity Whole-Body Vibration: A Useful Adjuvant in Managing Obesity? A Pilot Study

The use of whole-body vibration (WBV) for therapeutic purposes is far from being standardized and an empirical foundation for reporting guidelines for human WBV studies has only very recently been published. Controversies about safety and therapeutic dosage still exist. The present study aimed to investigate the metabolic and mechanical effects of low-intensity WBV according to the ISO 2631 norm on subjects with obesity. Forty-one obese subjects (BMI ≥ 35 kg/m2) were recruited to participate in a 3-week multidisciplinary inpatient rehabilitation program including fitness training and WBV training. During WBV the posture was monitored with an optoelectronic system with six infrared cameras (Vicon, Vicon Motion System, Oxford, UK). The primary endpoints were: variation in body composition, factors of metabolic syndrome, functional activity (sit-to-stand and 6-min walking test), muscle strength, and quality of life. The secondary endpoints were: modification of irisin, testosterone, growth hormone, IGF1 levels. We observed significant changes in salivary irisin levels, Group 2 (p < 0.01) as compared to the control group, while muscle strength, function, and other metabolic and hormonal factors did not change after a 3-week low-intensity WBV training with respect to the control group. Future studies are needed to further investigate the potential metabolic effect of low-intensity WBV in managing weight.
Productive, behavioral and physiological performance of feedlot Guzerat and 1⁄2 Guzerat × 1⁄2 Aberdeen Angus cattle

The objective of this study was to compare the productive, behavioral and physiological performance of feedlot Guzerat and 1⁄2 Guzerat × 1⁄2 Aberdeen Angus cattle. The experiment was conducted in a commercial feedlot for 80 days, between April and June 2016. Fifteen male Guzerat and 15 male 1⁄2 Guzerat-Aberdeen Angus cattle, both at the same age, with respective average initial weights of 381.27 and 401.34 ± 54.70 kg, were used. The animals were kept in collective pens, one for each breed group, with 14 m2 available per animal. Environmental conditions, respiratory frequency and behavior were evaluated for 12h00, starting at 06h00 and ending at 18h00. Feeding, rumination, rest, other activities and social, body care, anomalous, playful and locomotion behavior were observed. To examine the productive responses, initial weight, final weight, average daily weight gain, total weight gain, carcass yield, conformation and fatness were measured. Behaviors referring to feeding, rumination and other activities did not differ between the breed groups, except for the rest, playful and locomotion behaviors. A significant difference was detected (p < 0.05) for respiratory frequency and productive characteristics between the breed groups. In conclusion, 1⁄2 Guzerat × 1⁄2 Aberdeen Angus were superior to Guzerat cattle in productive performance. However, for behavioral and physiological variables, Guzerat animals exhibited better performance.
Ovarian follicular granulosa cells play a critical role onin

26 Objective: The aim of our study was to determine thatwhether ERβ regulates cell s 27 proliferation, steroidogenesis, autophagy and signalingsignalling pathways in bovine 28 ovarian granulosa cells in vitro. 29 Methods: In this study, bovine ovarian granulosa cells (BGCs) were cultured and 30 transfected with ERβ siRNA (si-ERβ) or overexpressiona plasmid overexpressing 31 ERβ (oe-ERβ), and CCK-8 kit was used to detectassess the cell proliferation. , 32 Rreal-time PCR was used to measure the genesgene transcription. Western-blot 33 blotting was used to determinemeasure proteins expression, and a specific kit was 34 used to measure the production of steroid hormones. 35 Results: The results showed the ERβ onaffects BGC proliferation for the first time 36 according to the gene transcription levels of FSHR, CYP19A1, HSD3β1 and STAR, 37 and onthe production of E2 and P4. ERβ was identified as an important nuclear 38 receptor that induced BGC autophagy based on the mRNA and protein expression 39 ofon the current results autophagyrelated genes mRNA level and protein expression. 40 MeanwhileFurthermore, the role of ERβ onin BGC autophagy was confirmed through 41 the treatment ofwith rapamycin (RAPA) or 3-methyladenine (3-MA) onin BGCs by 42 co-transfection with si-ERβ or oe-ERβ in BGCs, respectively. The results ofrelated to 43 AKT/mTOR signalling and its phosphorylation suggested that ERβ induces BGC 44 Ac c pt d Ar tic le
Para-Clinical and Immunological Evaluation in Buerger's Disease as a Suspected Autoimmune Disease: Case Series

Background: Autoimmunity causes the loss of normal immune homeostasis and involves the presence of autoantibodies and inflammation. Thromboangiitis obliterans or Buerger's disease (BD) refers to a type of vascular obstructive syndrome, with tobacco exposure accounting for disease formation and progression. However, the current understanding of autoimmunity is unclear in the context of BD, and the scientific findings are not enough to support autoimmune mechanisms. This study was aimed at investigating autoimmunity factors in patients with BD. Methods: Clinical and experimental examinations were performed on 80 patients with BD. The diagnostic work-up for autoimmunity was composed of IgM rheumatoid factor (RF), anti-nuclear antibodies (ANA), The erythrocyte sedimentation rate (ESR), anti-cyclic citrullinated peptide (CCP) antibodies, Antiphospholipid antibodies (APA), Anti-cardiolipin antibodies (ACLA), anti-double-stranded DNA (ds-DNA), and extractable nuclear antigen (ENA) profile. Immunomarkers were detected using the quantitative enzyme-linked immunosorbent assay (ELISA). Results: Raynaud's phenomenon (84.93%), cold sensitivity (76.25%), and claudication (73.75%) were the most common symptoms in the BD patients. Also, 64.29% represented with high ANA levels and positive RF, while 42.11% were found with increased ANA and ESR levels. The ANA/RF positive BD patients had ESR> 15 mm/hr and a high prevalence of cold sensitivity, claudication, and Raynaud's phenomenon (p> 0.05). Conclusions: There is a possibility of a non-specific autoimmune disposition among BD patients. RF and ANA could be considered for predicting disease progression.
Classifying aerosol particles through the combination of optical and physical-chemical properties_ Results from a wintertime campaign in Rome (Italy)

The “Carbonaceous Aerosol in Rome and Environs” (CARE) experiment took place at a Mediterranean urban background site in Rome (Italy) deploying a variety of instrumentation to assess aerosol physical-chemical and optical properties with high-time resolution (from 1 min to 2 h). In this study, aerosol optical properties, chemical composition, and size distribution data were examined with a focus on the analysis of several intensive optical properties obtained from multi-wavelength measurements of aerosol scattering and absorption coefficients. The spectral behaviour of several quantities related to both aerosol composition and size was explored, analysing their high-time resolved temporal patterns and combining them in order to extract the maximum information from all the available data. A methodology to separate aerosol types using optical data only is here proposed and applied to an urban area characterised by a complex mixture of particles. A key is given to correctly disentangle cases that could not be distinguished observing only one or few parameters, but that can be clearly separated using a suitable ensemble of optical properties. The SSCAAE, i.e. the wavelength dependence of the Single Scattering co-albedo 1-SSA (where SSA is the Single Scattering Albedo) that efficiently responds to both aerosol size and chemical composition – resulted to be the best optical intensive parameter to look at for the discrimination between episodes characterised by specific aerosol types (e.g. sea salt, Saharan dust) and more mixed conditions dominated by local emissions. However, this study also highlighted that it is necessary to combine temporal patterns of different optical parameters to robustly associate SSCAAE features to specific aerosol types. In addition, the complete chemical speciation and the hightime resolved size distribution were used to confirm the aerosol types identified via a combination of aerosol optical properties. Look-up tables with most suitable ranges of values for optical variables were produced; therefore, these pieces of information can be used at the same site or at locations with similar features to quickly identify the occurrence of aerosol episodes. Graphical frameworks (both from the literature and newly designed) are also proposed; for each scheme features, advantages, and limitations are discussed.
Fear of Hazards in Commodity Futures Markets Fernandez-Perez, Adrian and Fuertes, Ana-Maria and Gonzalez-Fernandez, Marcos and Miffre, Joelle

We examine the commodity futures pricing role of active attention to weather, disease, geopolitical or economic threats or “hazard fear” as proxied by the volume of internet searches by 149 query terms. A long-short portfolio strategy that sorts the cross-section of commodity futures contracts according to a hazard fear signal captures a significant premium. This commodity hazard fear premium reflects compensation for extant fundamental, tail, volatility and liquidity risks factors, but it is not subsumed by them. Exposure to hazard-fear is strongly priced in the cross-section of commodity portfolios. The hazard fear premium exacerbates during periods of adverse sentiment or pessimism in financial markets.
Depression of the melting temperature by moisture for α‐form crystallites in human hair keratin

DSC thermal analysis has been carried out for human hair samples with various moisture contents to investigate the melting temperature depression behavior of α‐form crystallites in human hair. This is achieved by adopting a novel technique using silicon oil as the thermal medium, which permits hair samples to retain a range of moisture contents in between completely dry and fully saturated. The results show that the melting temperature of the α‐form crystallites in human hair varies with moisture content from 205°C for dry hair to 155°C for the hair sample with moisture content of 23%. These experimental results are particularly useful for clarification of the conceptual ambiguities associated with the molecular properties of α‐helices and α‐form crystallites. Furthermore, the Flory–Huggins theory was employed to determine the water–helix interaction parameter (χ = 4.5) and the α‐form crystallinity of human hair (22%), a figure consistent with that obtained by the XRD method (21%). © 2004 Wiley Periodicals, Inc. Biopolymers, 2005
Miltefosine: A Miracle Drug for Meningoencephalitis Caused by Free-Living Amoebas

Meningoencephalitis caused by free-living amoebas (FLA) has a high mortality rate, and most treatments are ineffective. FLA includes Naegleria, Fowleri, Acanthamoeba, and Balamuthia mandrillaris (M). We explore the use of miltefosine in the treatment of one of these infections. The concerning mortality of the infection obligates us to look for more effective treatments for meningoencephalitis caused by FLA. During this review, we will consolidate the knowledge of using miltefosine in these three infections. We will investigate the mechanism by which the drug is effective in these infections as well. After this comprehensive review, we should assess if miltefosine improves the mortality and prognosis of the infection with the information collected. We used a Medical Subject Headings (MeSH) search on PubMed. Inclusion criteria included papers written in the English language and human subjects research for the past 25 years. Until today, there are no definitive guidelines to be followed when treating such patients. However, miltefosine has demonstrated promising results. Miltefosine decreases the usual mortality rate in the three infections; however, there are few reports due to the low frequency of these infections. Almost all cases we documented have survived. More information needs to be gathered for the use of miltefosine for these infections.
Cyclodextrin-Enhanced Biodegradation of Phenanthrene

The effectiveness of in situ bioremediation in many systems may be constrained by low contaminant bioavailability due to limited aqueous solubility or a large magnitude of sorption. The objective of this research was to evaluate the effect of hydroxypropyl-β-cyclodextrin (HPCD) on phenanthrene solubilization and biodegradation. Results showed that analytical-grade HPCD can significantly increase the apparent solubility of phenanthrene. The increase in apparent solubility had a major impact on the biodegradation rate of phenanthrene. For example, in the presence of 105 mg L-1 HPCD, the substrate utilization rate increased from 0.17 mg h-1 to 0.93 mg h-1 while the apparent solubility was increased from 1.3 mg L-1 to 161.3 mg L-1. As a result, only 0.3% of the phenanthrene remained at the end of a 48 h incubation for the highest concentration of HPCD tested (105 mg L-1). In contrast, 45.2% of the phenanthrene remained in the absence of HPCD. Technical-grade HPCD, which contains the biodegradable impurity pro.
Non-Blocking Synchronization in Operating Systems

Synchronizing shared objects using blocking techniques can come with significant performance and reliability issues, like deadlocks. Non-blocking algorithms can offer a solution for these problems by allowing multiple threads to modify shared data structures concurrently and atomically committing the result. However, despite this obvious advantage, their use in modern operating systems is quite rare. Still, quite a bit of research has gone into using non-blocking data structures in operating systems. This paper presents concepts for using non-blocking algorithms in the context of operating systems and discusses their advantages and disadvantages. Both a straightforward methodology for wait-free locking with helping and a cooperative non-blocking scheduler are covered.
Functional electrical properties of the endothelium in lymphatic vessels of the guinea‐pig mesentery

1 The resting and agonist‐stimulated properties of endothelial cells and electrical communication between the endothelium and smooth muscle were investigated in open segments of guinea‐pig mesenteric lymphatic vessels using intracellular microelectrodes. 2 Endothelial cells had a mean resting membrane potential (RMP) of – 71.5 ± 0.5mV (n= 100) which was significantly different from the value of −60.8 ± 1.1 mV (n= 75) recorded in smooth muscle. 3 Acetylcholine (ACh, 5–1 μm) generally evoked an initial hyperpolarization followed by depolarization (mean 3.4 ± 0.5 mV and 15.4 ± 1.0 mV, respectively, n= 75). 4 Ca2+‐activated K+ channels were likely to underlie the ACh‐induced hyperpolarization as this response exhibited an increase in membrane conductance, was larger in 0.5 mm K+ solution and was blocked by charybdotoxin (50 nm). 5 The endothelium did not exhibit a response to nitric oxide (NO) as the NO‐donor sodium nitroprusside did not alter the RMP and the electrical responses to ACh were not affected by the NO‐synthase inhibitor Nω‐nitro L‐arginine at a concentration which markedly inhibited smooth muscle hyperpolarization. 6 Electrical coupling between the endothelium and smooth muscle was not functional as there was extremely limited electrical continuity (1 in 12, endothelial/smooth muscle cell simultaneous recordings) and bradykinin, noradrenaline and isoprenaline caused different electrical responses in the two cell types. 7 These results provide the first description of RMP and electrical responses to various agonists in the lymphatic endothelium and its lack of functional electrical coupling with the smooth muscle.
Toward A ‘Pro-biotic’ Study of Organizing

Perhaps, I began thinking as I reflected on this book, we should add a second hyphen to the term ‘de-colon-izing’ when speaking of organizational knowledge. The colonic metaphor resonates with a theory one of my mentors once espoused as the ‘Pampers theory’ of organizational knowledge production (Calàs, 1990). I will not go into that theory beyond noting in passing that Pampers is the trade name of a popular disposable nappie. Into a field ready for rigorous de-colon-ization, Prasad et al. have produced a valuable resource for developing more, well, ‘probiotic’ organizational knowledge, one contributing to better (post)colonic health. I encourage organizational theorists of all perspectives to make Postcolonial Theory and Organizational Analysis a part of their libraries.
Metal ion content of some Greek wines

Summary The concentrations of fourteen metal ions were determined in 113 commercial Greek wines by atomic absorption or emission spectroscopy. The ions of K (1440 mg l−1), Na (27.7 mg l−1), Mg (101 mg l−1) and Ca (31.9 mg l−1) were found in greatest concentration. Among the others, mean Fe and Al concentrations were 3.51 and 2.35 mg l−1, respectively; Cu, Zn and Pb were between 0.20 and 0.41 mg l−1; and Li, Ni, Cr, Co and Cd were < 0.10 mg l−1. These results are compared critically with published data on wines of widely differing origins.
Espousal of Ma–ori Values in the Workplace

This study investigated the relationship between organisational espousal of cultural group values and organisational commitment and citizenship behaviours. The study focused on Ma–ori employees, and their perceptions of the extent to which their organisation espoused some of the central values of Te Ao Ma–ori (the Ma–ori world), specifically manaakitanga (caring), whakawhanaungatanga (relationships), wairuatanga (spirituality), auahatanga (creativity) and kaitiakitanga (guardianship). Furthermore, the role of identification with the Ma–ori culture was investigated as a potential moderator of the relationship between organisational espousal of each of the Ma–ori values and the outcome variables. The methodology was tested in a sample of 91 Ma–ori employees from Ma–ori-led organisations. The participants completed an anonymous online survey. The data was analysed using moderated hierarchical regression analysis. Organisational espousal of the composite Ma–ori values wairuatanga and whakamana tangata was reciprocated with organisational commitment. Although no significant main effects were found with respect to Ma–ori values and organisational citizenship behaviours the interaction of identification with Ma–ori culture with Ma–ori values influenced this outcome; those with lower identification with Ma–ori culture, and who also perceived that their organisation did not espouse Ma–ori values, reported lower levels of organisational citizenship behaviours. Taken together, the results suggest that organisations benefit in being aware of, and incorporating values of the cultural groups represented in the workforce with their overall practices, as this is manifested in higher commitment and citizenship behaviours among employees. O Ma–ori values