Miracle-dz/UniFAR-FTUs huggingface dataset:
Making the Case for Standardized Outcome Measures in Exercise and Physical Activity Research in Chronic Kidney Disease

Physical activity and exercise are core components of lifestyle modification strategies for the management of chronic kidney disease (CKD). Yet, physical activity levels have consistently remained poor across all stages of CKD. Exercise interventions, including aerobic and resistance training, and lifestyle interventions promoting physical activity, have been shown to improve a multitude of clinical endpoints and factors important to patients; however, despite the evidence, the provision of physical activity in clinical practice is still inadequate. The usefulness of any study hinges on the adequacy and clinical relevance of the outcomes and outcome measures used. Inconsistent reporting and wide disparities in outcome use across studies limit evidence synthesis to help guide clinical practice. The kidney exercise and physical activity field has been particularly prone to inconsistent outcome reporting. To ensure research is relevant and able to influence clinical practice and future research, we need to ensure the use (and reporting) of standardized, relevant outcome measures. Core outcome sets (COS) have been widely developed across many chronic conditions, yet these COS have not been tailored to physical activity and exercise in CKD. Outcomes in clinical research need to be relevant to the intervention being employed. From this perspective, we summarize the importance that standardizing outcomes and outcome measures may have in relation to physical activity and exercise interventions for people living with kidney disease.
Using chemically modified Ocimum tenuiflorum as an efficient and low-cost biosorbent for removing Congo red from aqueous solutions

The powder of Ocimum tenuiflorum leaves (OtLP) was modified by ZnCl2, H2C2O4, or CuS. The modified powders were characterized and applied as adsorbents for the first time to adsorb Congo red (CR). The effects of the most potent experimental variables on the CR adsorption by the chosen adsorbent were examined. Kinetic, isotherm, and thermodynamic constants were investigated. The best adsorbent was discovered to be the powder modified by ZnCl2 and CuS, which removed 97.82% of the CR and had a pore size of 1349.0 Å, pore volume of 2.1211 cm³. g−1, and a 281.16 m2.g−1 surface area. This adsorption followed models of second order and Langmuir for its kinetics and isotherms, respectively. Thermodynamic analyses proved that this adsorption is both heat-absorbing and spontaneous. The high uptake capacities (625.000, 714.286, and 769.231 mg.g−1) obtained in this study prove that this adsorbent will gain a significant attention in the field of water decontamination.
A Peer-Led Anatomy Dissection Experience for Second-Year Medical Students

In the fall of 2021, a cohort of second-year osteopathic medical students took part in a regional dissection experience led by their peers. During the students’ first year of medical school, when they would have normally participated in anatomy dissections, they instead took part in a prosection-based gross anatomy course due to COVID restrictions. Many students requested the opportunity to learn dissection techniques, dissect regions of interest for specialties, and participate in this medical school “rite of passage” when COVID restrictions eased. This article describes the planning and implementation of a regional dissection program for 42 second-year medical students that occurred outside normal curricular hours at the West Virginia School of Osteopathic Medicine (WVSOM). This program was led by two second-year osteopathic medical students who had previously performed a full donor dissection as well as assisted in teaching at the college level. One of the main advantages of this program was the use of a limited number of donors compared to the large number of students who were able to participate in dissection in a meaningful way. A disadvantage was that each pair of students was only able to dissect one region of the body during their sessions. A quality improvement survey was conducted after the experience and 26% of participants provided feedback for potential future programs at WVSOM. Students reported enjoying the experience and becoming more comfortable using dissection instruments. This dissection program could be used as a template for an anatomy elective, a brief introduction to dissection, or a summer course. https://doi.org/10.21692/haps.2023. 005
Rock Phosphate Solubilizing Potential of Soil Microorganisms: Advances in Sustainable Crop Production

Phosphorus (P) is one of the most important elements required for crop production. The ideal soil pH for its absorption by plants is about 6.5, but in alkaline and acidic soils, most of the consumed P forms an insoluble complex with calcium, iron, and aluminum elements and its availability for absorption by the plant decreases. The supply of P needed by plants is mainly achieved through chemical fertilizers; however, in addition to the high price of these fertilizers, in the long run, their destructive effects will affect the soil and the environment. The use of cheap and abundant resources such as rock phosphate (RP) can be an alternative strategy for P chemical fertilizers, but the solubilization of P of this source has been a challenge for agricultural researchers. For this, physical and chemical treatments have been used, but the solution that has recently attracted the attention of the researchers is to use the potential of rhizobacteria to solubilize RP and supply P to plants by this method. These microorganisms, via. mechanisms such as proton secretion, organic and mineral acid production, siderophore production, etc., lead to the solubilization of RP, and by releasing its P, they improve the quantitative and qualitative performance of agricultural products. In this review, addressing the potential of rhizosphere microbes (with a focus on rhizobacteria) as an eco-friendly strategy for RP solubilization, along with physical and chemical solutions, has been attempted.
The Influence of Convenience, Expediency, and Trust on Consumers' Decisions in Using Digital Platforms as A Means of Paying Zakat, Infaq, and Alms

Advances in technology and information have made zakat, infaq, and alms managers innovate and collabo-rate with various digital platforms in Indonesia which aim to facilitate the distribution of zakat, infaq, and alms (ZIS). This research was conducted to find out and analyze the variables of convenience, expediency, and trust that influence consumers' decisions in using digital platforms to pay zakat, infaq, and alms. The sample used in this study was 155 respondents who were domiciled in the Jakarta, Bogor, Depok, Tange-rang, and Bekasi (Jabodetabek) regions. In the selection of samples, this study used purposive sampling techniques and data processing was carried out using the IBM Version 26.0 Statistical Package for the So-cial Sciens (SPSS) application. The results showed that all independent variables, namely convenience, expediency, and trust have an influence both partially and simultaneously on consumers' decisions to use digital platforms as a means of paying zakat, infaq, and alms. The easier it is to use, the benefits are felt, and consumer trust in digital platforms when paying for ZIS using digital platforms can increase consum-ers' decision to use digital platforms as a means of paying for ZIS.
Liquid Film Thickness for Gas-Liquid Annular Flow Across Grid Spacer with Vanes in Simple 3 × 3 Rod Bundle Channel

Abstract This study reports the effects of the grid spacer with mixing vane (MV) on gas velocity for air single-phase flow and liquid film thickness for air-water two-phase annular flow in a 3 × 3 rod bundle channel. To investigate the effects of the shape of the spacers, three kinds of spacers were installed into the channel: spacer without MV (without MV), spacer with four MVs (4-MV30), and spacer with two MVs (2-MV30). The 4-MV30 and 2-MV30 had vanes that were inclined 30 deg from the vertical axis. Gas velocity was measured with a hot-wire anemometer and liquid film thickness was measured with the constant electric current method. From the gas velocity measurement, it was found that the irregularities in the velocity distribution became smaller toward downstream of the spacer. For the 2-MV30, the flow distribution was asymmetric and the flow was biased. From the liquid film thickness measurement, it was found that the liquid film thickness became thicker downstream of the spacer.
Low-temperature relaxor state induced by epitaxial compression in PbSc 0.5 Nb 0.5 O 3 films

The use of high-performance perovskite-structure epitaxial relaxor ferroelectric films [S. H. Baek et al., Science 334, 958 (2011)] is hindered by the lack of knowledge of epitaxial effects therein. It is experimentally shown here that a biaxial epitaxial compression can favor the relaxor state over ferroelectricity. The absence of the ferroelectric transition and the existence of the low-temperature relaxor state are evidenced by a combination of x-ray diffraction, dielectric, polarization, and optical studies of PbSc${}_{0.5}$Nb${}_{0.5}$O${}_{3}$ films epitaxially grown on La${}_{0.5}$Sr${}_{0.5}$CoO${}_{3}$/MgO(001). This finding is beyond existing models of polarization in perovskite-structure epitaxial films and beyond the established ability to induce ferroelectricity by an epitaxial strain.
Continuity of Early Intervention Services in New York City During the COVID-19 Pandemic

In response to COVID-19, the New York City Early Intervention (EI) Program rapidly transitioned from in-person to teletherapy services. We describe the timing of service resumption among children who received EI services between March 1 and March 17, 2020. The proportion of children who transitioned to teletherapy-only was 25% as of March 24, rising to 78% by July 6. By December 31, 2020, 87% of the cohort had resumed either teletherapy or in-person services. Child age, race, language, and neighborhood poverty all predicted service resumption timing. Children with a diagnosis of autism spectrum disorder were more likely to transition to teletherapy, and children with only 1-2 domains of delay were more likely to discontinue services altogether. Continuity of EI services during the COVID-19 public health emergency was a critical priority. Timely policy changes facilitated swift return to services and avoided exacerbation of the long-standing racial disparities in access to EI services.
Using reflection to demonstrate development of active citizenship and critical consciousness through authentic and locally based projects

ABSTRACT Concepts such as active citizenship and critical consciousness are increasingly relevant to enable students to meet the challenges of tomorrow. Additionally, self-reflection is a powerful tool to observe the development of abstract concepts such as these. This qualitative exploratory study examined the extent to which university students in Colombia enhanced their critical consciousness and a sense of active citizenship through projects focused on cases of violence against social leaders in their region. During the project, 93 students in four academic cohorts wrote a total of 155 reflections related to their experiences. These were analyzed using qualitative content analysis with the AtlasTi software. The results evidenced a shift in students’ critical consciousness including a deeper understanding, a recognition of significance, an acknowledgement of privilege, and an awareness of the connection between local and global issues in relation to the topic of the project. In addition, traits of active citizenship were observed such as a sense of collective responsibility, a desire to contribute, a sense of empowerment, and growth in empathy. This research demonstrates the potential for authentic locally based project topics for developing active citizenship and enhancing critical consciousness as well as reinforcing the potential for reflections to demonstrate such development.
Pathways From Individual Characteristics to Subjective Consequences of Sex: The Mediating Role of Risky Sexual Encounters

Abstract Objectives: This study examined associations between young adults’ psychological characteristics and psychosocial consequences of sex, and whether risky sexual encounters mediated these associations. Methods: College students (N = 265; M age = 19.49) completed questionnaires concerning risky sexual relationships, behaviors, situations, and psychosocial consequences during their most recent encounter and over the last year. Results: Sexual restraint indirectly predicted positive consequences of the most recent encounter via risky sexual behaviors. Sexual restraint and permissiveness predicted positive and negative consequences over the past year via risky relationships. Conclusions: Psychological characteristics may influence the likelihood of risky sexual encounters, thereby influencing consequences.
No Consistent Simulated Trends in the Atlantic Meridional Overturning Circulation for the Past 6,000 Years

The Atlantic Meridional Overturning Circulation (AMOC) is a key feature of the North Atlantic with global ocean impacts. The AMOC's response to past changes in forcings during the Holocene provides important context for the coming centuries. Here, we investigate AMOC trends using an emerging set of transient simulations using multiple global climate models for the past 6,000 years. Although some models show changes, no consistent trend in overall AMOC strength during the mid‐to‐late Holocene emerges from the ensemble. We interpret this result to suggest no overall change in AMOC, which fits with our assessment of available proxy reconstructions. The decadal variability of the AMOC does not change in ensemble during the mid‐ and late‐Holocene. There are interesting AMOC changes seen in the early Holocene, but their nature depends a lot on which inputs are used to drive the experiment.
Point Optimal Invariant Tests of a Unit Root in Models with Structural Change

This study proposes tests for the null hypothesis of a unit root against shifting trend stationary alternatives. In particular, models with structural change in the form of level or trend shifts are studied. Roots local-to-unity are addressed in models with structural change and asymptotic power functions of the tests are derived using local-to-unity asymptotic framework. These tests have good power properties against shifting trend stationary alternatives. Tests in the presence of multiple shifts are also examined. The asymptotic distributions of the tests are derived under exogenous and endogenous shift point assumptions. The asymptotic and ﬁnite sample percentiles of the tests are tabulated using Monte Carlo integration. Monte Carlo simulations reveal that tests have good power and size properties against various alternatives.
Implication of the Transmembrane Domain in the Interleukin 10 Receptor Platform Oligomerisation

Interleukin 10 (IL-10) exerts anti-inflammatory and immune regulatory roles through its fixation to the IL-10 receptor (IL-10R). The two subunits (IL-10Rα and IL-10Rβ) organise themselves to form a hetero-tetramer to induce the activation of the transcription factor STAT3. We analysed the activation patterns of the IL-10R, especially the contribution of the transmembrane (TM) domain of the IL-10Rα and IL-10Rβ subunits, as evidence accumulates that this short domain has tremendous implications in receptor oligomerisation and activation. We also addressed whether targeting the TM domain of IL-10R with peptides mimicking the TM sequences of the subunits translates into biological consequences. The results illustrate the involvement of the TM domains from both subunits in receptor activation and feature a distinctive amino acid crucial for the interaction. The TM peptide targeting approach also appears to be suitable for modulating the activation of the receptor through its action on the dimerization capabilities of the TM domains and thereby constitutes a potential new strategy for the modulation of the inflammation in pathologic contexts.
Incremental Recomputation of Pig Latin’s Nest and Unnest Operators

This master’s thesis addresses the maintenance of pre-computed structures, which store a frequent or expensive query, for the nested bag data type in the high level work-flow language Pig Latin. This thesis defines a model suitable to accommodate incremental expressions over nested bags on Pig Latin. Afterwards, the partitioned normal form for sets is extended with further restrictions, in order to accommodate the nested bag model, allow the Pig Latin nest and unnest operators revert each other, and create a suitable environment to the incremental computations. Subsequently, the extended operators – extended union and extended difference – are defined for the nested bag data model with the partitioned normal form for bags (PNF Bag) restriction, and semantics for the extended operators are given. Finally, incremental data propagation expressions are proposed for the nest and unnest operators on the data model proposed with the PNF Bag restriction, and the proof of correctness is given.
The Immunosuppressive Roles of PD-L1 during Influenza A Virus Infection

The clinical benefits of targeting programmed death-ligand 1 (PD-L1) in various cancers represent a strategy for the treatment of immunosuppressive diseases. Here, it was demonstrated that the expression levels of PD-L1 in cells were greatly upregulated in response to H1N1 influenza A virus (IAV) infection. Overexpression of PD-L1 promoted viral replication and downregulated type-I and type-III interferons and interferon-stimulated genes. Moreover, the association between PD-L1 and Src homology region-2, containing protein tyrosine phosphatase (SHP2), during IAV/H1N1 infection was analyzed by employing the SHP2 inhibitor (SHP099), siSHP2, and pNL-SHP2. The results showed that the expressions of PD-L1 mRNA and protein were decreased under SHP099 or siSHP2 treatment, whereas the cells overexpressing SHP2 exhibited the opposite effects. Additionally, the effects of PD-L1 on the expression of p-ERK and p-SHP2 were investigated in PD-L1-overexpressed cells following WSN or PR8 infection, determining that the PD-L1 overexpression led to the decreased expression of p-SHP2 and p-ERK induced by WSN or PR8 infection. Taken together, these data reveal that PD-L1 could play an important role in immunosuppression during IAV/H1N1 infection; thus, it may serve as a promising therapeutic target for development of novel anti-IAV drugs.
Evolutionary Programming Using Mutations Based on the t Probability Distribution

Consulted some previous mutations,this paper proposed an evolutionary programming(EP)using mutations based on the t probability distribution(tEP). The t probability distribution can connect with Gaussian and Cauchy probability distribution.Its variance is changeable by adjusting degree of freedom n.Rules of t mutations according to the change ofn and standard deviation are analyzed by simulations,and the relationship among number of generations,standard deviation and minimum fitness are briefly summarized.Then an EP using adaptive t mutations(AtEP)is put forward at the end.The AtEP uses several t mutations with different n at the same time,so it can integrate the advantages of Gaussian and Cauchy mutation.And simulation evidence shows the algorithm is better than classical EP algorithm.
Observations of GRBs in the mm/submm range at the dawn of the ALMA era

Abstract Gamma-ray bursts (GRBs) generate an afterglow with an emission peaking in the millimetre and submillimeter (mm/submm) range during the first hours to days, making the study in these wavelengths of great importance. Here we give an overview of the data that has been collected for GRB observations in this wavelengths until September 2011. The total sample includes 102 GRBs, of which 88 have afterglow observations, and the rest are only host galaxy searches. The 22 detections cover the redshift range between 0.168 and 8.2 and have peak luminosities that span 2.5 orders of magnitude. With the start of the operations at ALMA, the sensitivity with respect to previous facilities has already improved by over an order of magnitude. We estimate that, once completed, ALMA will be able to detect ~98 % of the afterglows. This proceeding is based on the work published by de Ugarte Postigo et al. (2012).
Dynamic Magnetoelectric Effect of Soft Layered Composites with a Magnetic Elastomer

Multilayered magnetoelectric materials are of great interest for investigations due to their unique tuneable properties and giant values of magnetoelectric effect. The flexible layered structures consisting of soft components can reveal lower values of the resonant frequency for the dynamic magnetoelectric effect appearing in bending deformation mode. The double-layered structure based on the piezoelectric polymer polyvinylidene fluoride and a magnetoactive elastomer (MAE) with carbonyl iron particles in a cantilever configuration was investigated in this work. The gradient AC magnetic field was applied to the structure, causing the bending of the sample due to the attraction acting on the magnetic component. The resonant enhancement of the magnetoelectric effect was observed. The main resonant frequency for the samples depended on the MAE properties, namely, their thickness and concentration of iron particles, and was 156–163 Hz for a 0.3 mm MAE layer and 50–72 Hz for a 3 mm MAE layer; the resonant frequency depended on bias DC magnetic field as well. The results obtained can extend the application area of these devices for energy harvesting.
How Job Satisfaction Mediating the Influence of Non-Physical Work Environment and Career Development on Employee Turnover Intention at PT XYZ

The purpose of this study was to determine the effect of the non-physical work environment as well as ca-reer development on job satisfaction and its impact on turnover intention at PT. XYZ. This research is quantitative, using path analysis research tools and survey research methods to collect primary data by dis-tributing questionnaires to 171 employees of PT. XYZ as the respondent. The results of the study indicate that there is a significant influence of the non-physical work environment and career development on turn-over intention, which is mediated by job satisfaction at PT. XYZ. A pleasant non-physical work environ-ment and the implementation of career development programs can reduce the level of turnover intention of employees of PT. XYZ, which is supported by the feeling of getting job satisfaction in completing tasks and responsibilities within the company. The implication of the results of this study is that PT. XYZ needs to improve human relationships both vertically and horizontally, design career planning programs, and design attractive financial and non-financial benefits plans.