Miracle-dz/UniFAR-FTUs huggingface dataset:
Clinical, laboratory features and minimal residual disease levels in childhood acute lymphoblastic leukemia at Hue Central Hospital, Viet Nam

Nguyen Thi Kim Hoa1, Phan Hung Viet2, Tran Kiem Hao1, Bui Binh Bao Son1,2 1Pediatric Center, Hue Central Hospital, Viet Nam 2Department of Pediatrics, Hue University of Medicine and Pharmacy, Viet Nam Characteristics of childhood acute lymphoblastic leukemia Clinical, laboratory features and minimal residual disease levels in childhood acute lymphoblastic leukemia at Hue Central Hospital, Viet Nam
Implementing localised curriculum drawing on a funds of knowledge perspective

In recent years in New Zealand, there has been a policy shift towards schools ‘localising’ the national curriculum to align with the context, aspirations, and knowledge of the local community and student population. In relation to mathematics education, this requires educators to understand and value the mathematical connections between diverse students’ funds of knowledge and use these to develop mathematical tasks. This article draws on interview responses from a case study of eight teachers from one low socio-economic, culturally diverse school to investigate their initial perceptions and actions to develop an appropriate localised mathematics curriculum drawing on diverse students’ funds of knowledge. The findings indicate that teachers viewed it as important to use real and relevant contexts in mathematics teaching. Interview responses indicated that both students and their families were seen as important sources of information. However, there were challenges for teachers to recognise students’ funds of knowledge related to mathematics beyond schooling or generic experiences.
Properties of Cellulose Fibres and Waste Plastic Modified Porous Friction Course Mixes

This paper summarizes the laboratory investigation on porous friction course mixes that were modified with cellulose fibres and waste plastics. Porous friction course mixes of three different aggregate gradations were tested for predetermined binder content. The influence of each modifier on the volumetric properties, permeability, aged abrasion loss, and moisture susceptibility of porous friction course mixes were evaluated. In order to determine the significance level of effect of modifiers on the above properties, the tests for analysis of variance (ANOVA) and Tukey’s multiple mean comparisons were performed. Results of statistical analyses indicate that the gradations are major source of variations in all response properties. However, modifiers too appreciably contributed in reducing the moisture-induced damages. The findings suggest that shredded waste plastics are potentially useful as modifiers to porous friction course mixes.
Overexpression of miR-664 is associated with poor overall survival and accelerates cell proliferation, migration and invasion in hepatocellular carcinoma

Introduction Hepatocellular carcinoma (HCC) is one of the leading causes of cancer-related death worldwide. This study aimed to investigate the expression patterns of microRNA-664 (miR-664) in HCC tissues and cells, and assess its clinical significance and functional role in HCC. Patients and methods One hundred and thirty-four paired HCC and non-cancerous tissues were collected from patients who underwent surgery in Qianfoshan Hospital affiliated to Shandong University (Shandong, China) between 2009 and 2012. Expression of miR-664 was measured by quantitative real-time polymerase chain reaction (qRT-PCR). Prognostic value of miR-664 in HCC was evaluated using Kaplan–Meier survival analysis and Cox regression analysis. Cell proliferation was analyzed using the CCK-8 assay, and cell migration and invasion of HCC cells was evaluated by the Transwell assay. Results Expression of miR-664 was significantly upregulated in HCC tissues and cells when compared with the normal controls (all P<0.05). MiR-664 expression was associated with lymph node metastasis, TNM stage and differentiation (all P<0.05) in the HCC patients. High miR-664 expression predicted poor overall survival (log-rank P=0.004) and acted as an independent prognostic factor (HR =1.945, 95% CI=1.078–3.508, P=0.027). According to cell experiments, the upregulation of miR-664 could promote, whereas the downregulation of miR-664 could inhibit proliferation, migration and invasion of HCC cells (all P<0.05). SIVA1 was predicted as a direct target gene of miR-664 in HCC. Conclusion All data indicated that overexpression of miR-664 is associated with poor prognosis of HCC patients, and may enhance tumor progression of HCC by targeting SIVA1. MiR-664 may be a candidate therapeutic target for HCC treatment.
When Practice Fails to Reduce Racial Bias in the Decision to Shoot: The Case of Cognitive Load

Practice improves performance on a first-person shooter task (FPST), increasing accuracy and decreasing racial bias. But rather than simply promoting cognitively efficient processing, we argue that the benefits of practice on a difficult, cognitively demanding task like the FPST rely, at least in part, on resource-intensive, cognitively effortful processing. If practice-based improvements require cognitive resources, then cognitive load should compromise the value of practice by depriving trained participants of the cognitive resources on which they depend. This experiment shows that inducing cognitive load eliminates the benefits of training, leading to an increase in racial bias, as predicted.
The Strength Characteristics of the Saline Soil after Leached

Through the permeability leach test,this paper analyzed the change rule of the strength parameters of the saline soil with salt content. The results show that the more salt the saline soil had before leached,the more cohesive force and internal friction angle is reduced after it was leached, and the relationship between them can be explained through hyperbolic function.According to the soil shear strength theory, deduced the calculation formula of the strength after leached. Through the verification, the calculation values of the strength parameter and measured values were very close. Shear strength calculation formula offers a theoretical basis for the design and the foundation stability calculation of buildings in saline soil areas.
Influences of Intermittent Anaerobic Exercise Program on Physical Fitness and Plasma Lactate, Oxidant and Anti-oxidant Status in Smokers and Non-smokers Judo Players.

Background: There is evidence of smoking’s negative impact and physical activity’s positive impact on long-term health. However, evidences regarding the association between smoking and exercise activity and the independent effects of these factors on antioxidant defense are lacking. The aim of this study is to investigate the association between smoking and the intermittent anaerobic exercise on the physical fitness, oxidant and antioxidant status in Judo player. Methods: Twenty male Judo player student from Department of Physical Education Al- Azhar University were enrolled in the study. They were of 2 groups, Non-smokers (NS) and smokers (SM). Both groups were subjected to regular Judo training program (2 hours/day, 3 sessions/week for 12 weeks). Also, both groups were subjected to an effort test (running of submaximal intensity until exhaustion ) and record of the maximum oxygen capacity (VO2max) using an ergometric bicycle. Heart rate (HR), mean arterial blood pressure (MBP) were recorded and blood samples were taken pre and post-effort test for determination of malondialdehyde (MDA),total antioxidant capacity (TAC), uric acid (Ua) and lactate (La) in the plasma. Also the time to exhaustion was recorded during the effort test. These measures were performed pre and post the training program. Results: At rest the pre-program data of SM showed significantly higher H.R. , and plasma MDA ,and significantly lower TAC with tendency to increase in MBP and La levels, and decrease in VO2max, and Ua levels compared to NS. Before program and in response to acute exercise SM showed significantly higher H.R, MDA and La levels with significantly lower TAC, Ua and time to exhaustion compared to NS. On the other hand, after the program and in response to acute exercise, SM showed more pronounced significantly higher HR, MBP, MDA and La with significantly lower VO2max, time to exhaustion and TAC with insignificant changes in the Ua compared to the NS that showed significant increase in the Ua levels with insignificant changes in the MDA, TAC and the La levels in response to acute exercise. In response to the training program, SM showed significantly higher HR, MBP, MDA and La levels, with significantly lower VO2max, time to exhaustion, and TAC, and insignificant changes in the Ua levels compared to NS. Conclusion: We conclude that cigarette smoking has a significant detrimental effects on cardiovascular fitness, physical endurance, TAC and lipid peroxidation that all worsened by the intermittent anaerobic exercise. On the contrary , this type of training is beneficial in nonsmokers. Also we demonstrated that smoking prevent the beneficial effects of exercise , so smoking should be avoided in Judo players. Smokers should be given strong encouragement to stop smoking and to improve physical fitness.
Investigating the Role of English Text in Character Building in the Context of the Private Institutes of Pakistan

English text from grade I is analyzed through a designed questionnaire. The questionnaire is based on Krawthol’s affective domain and administered among teachers and administrators of all campuses with in the same institute to find the role of English text in character building of students. Purposive sampling technique is used to select a sample of 76 participants from the defined population. Data derived from questionnaires is statistically investigated, such as t-test, ANOVA, Cohan’s d, eta and percentages. The survey result clearly shows the positive contribution of Grade I English text in character building of the students, presented in form of tables. Moreover, the research has imperative suggestions for teachers and curriculum developers for further research in the field of character building at elementary level.
Costal Cartilages Overgrowth Doesn’t Induce the Deformation of the Chest Wall in Experimental Animals

Introduction: Many consider overgrowth of the costal cartilages to be the etiological factor for chest wall deformities in children. The aim of this study is to investigate if induced overgrowth of the costal cartilages leads to the deformation of the chest wall in an animal model. Material and Methods: We injected insulin growth factor 1 (IGF1) solution directly under the perichondrium of the last three costal cartilages of rat pups. We used two different concentrations: 50 μg/ml (E50) and 100 μg/ml (E100). The procedure was repeated once per week for five consecutive weeks. Seven days from the last administration of injections, the animals were euthanized. We assessed the shape and measured the diameters of the thoracic cage. The last three costal cartilages were dissected; the samples were prepared and examined in light microscopy. Results: In E100 the sagittal and coronal diameters of the rib cage were larger than E50 and control groups but without any deformation of the chest wall. The microscopic examinations revealed an anabolic pattern in E100.Conclusion: Locally administered IGF1 stimulates, in a dose dependent manner, in-vivo cellular growth and multiplication in the costal cartilages. The induced overgrowth of the costal cartilages however, didn’t result in the deformation of the chest wall.
Factors influencing technical innovation in construction SMEs: an Australian perspective

Purpose – The intent of this research is to determine whether any common lessons can be drawn from the experience of individuals who have gone against the trend and delivered successful technical innovations in construction small and medium enterprises (SMEs). Design/methodology/approach – A value tree of contributing factors to technical innovation was developed from the literature and tested by surveying established technical innovators using analytic hierarchy process methodology. This approach aimed at capturing the experience of company decision makers who manage to deliver successful change with limited resources.Findings – The results reveal the importance of supportive clients and performance‐based building standards for innovative practice in construction. Significant differences were observed between small and medium‐sized companies and between product and process innovators.Research limitations/implications – In order to avoid a skewed sample, considerable effort was made to ensure that all surv.
Complete mitochondrial genome of the Yangtze grenadier anchovy, Coilia Brachygnathus (Clupeiformes: Engraulidae) from the upper Yangtze River

Abstract The Yangtze grenadier anchovy, Coilia brachygnathus, is a commercial fishery species in the middle and lower Yangtze River of China. Here, we describe a complete mitochondrial genome from the newly found population of C. brachygnahus in the upper Yangtze River. It was 16,857 bp in size and encodes for 2 rRNAs, 22 tRNAs, 13 protein-coding genes as well as a D-loop control region. Phylogenetic analysis confirmed the evolutionary relationship of the C. brachygnathus in the upper Yangtze to other five species of the genus Coillia. The mitochondrial genome would help to elucidate the origin of the new population of C. brachygnathus.
Determination of minimum number of random SNP for accurate population classification in rice (Oryza sativa L.)

Background: Classification of germplasm collections is of great importance for both the conservation and utilization of genetic resources. Thus, it is necessary to estimate and classify rice varieties in order to utilize these germplasms more efficiently for rice breeding. However, molecular classification of large germplasm collections can be costly and labor-intensive. Development of an informative panel of a few markers would allow for rapid and cost-effective assignment of crops to genetic sub-populations.Results: Here, the minimum number of random SNP for rice classification (MNRSRC) was studied using a panel of 51 rice varieties belonging to different sub-groups. Through the genetic structure analysis, the rice panel can be obviously divided into five subgroups. The estimation of the MNRSRC was performed using SNP random sampling method based on genetic diversity and population structure analysis. In the genetic diversity analysis, statistical analysis of the coefficient of variation (CV) was performed for MNRSRC estimation, and we found that CV variation tended to plateau when the number of SNP was around 200, which was verified by the both cross-validation error of K value and correlation analysis of genetic distance. When the number of SNPs was greater than 200, the distribution of cross-validation error value tended to be similar, and correlation coefficients, almost greater than 0.95, exhibited small range of variation. In addition, we found that MNRSRC might not be affected by the number of varieties and the type of varieties.Conclusion: The estimation of the MNRSRC was performed using SNP random sampling method based on genetic diversity and population structure analysis. The results demonstrated that at least about 200 random filtered SNP loci were required for classification in a rice panel. In addition, we also found that MNRSRC might not be affected by the number of varieties and the type of varieties. The study on MNRSRC in this study can provide a reference and theoretical basis for classification of different types of rice panels.
Miniaturised antennas using artificial magnetic materials with fractal hilbert inclusions

Artificial magnetic materials based on fractal Hilbert curves are used as a substrate to increase effective permeability, thus leading to antenna size miniaturisation. A miniaturised patch antenna with miniaturisation factor of 5.3, and impedance bandwidth of 2.11% is designed, numerically tested, fabricated, and measured.
Fatigue Failures of Centrifugal Impeller Disks

An unusual centrifugal impeller disk failure has been encountered in one of the stages of a multistage air compressor. The failure occurred when a triangular piece of metal separated from the disk at the rim of the impeller disk. Stress analyses show that the steady hoop stresses at the rim were very low. Metallurgical observations indicate that the failure was caused by high cycle fatigue in cast 17-4 PH steel. A modal analysis shows that the failure can be explained by a resonance condition. The excitation of the backward rotating tangential nodal pattern by the stationary vaned diffusers just downstream of the impeller rim causes this resonance condition. Avoiding the resonance condition by changing the number of diffuser vanes has eliminated the failures.Copyright © 1999 by ASME
The BAFF/APRIL system: emerging new and unappreciated biomarkers in autoimmunity

Belimumab, a new drug targeting a molecule named BAFF, is efficient in some patients suffering from an incurable illness called lupus. No tool is available enabling physicians to select patients who could benefit from belimumab. BAFF and/or related molecules, found in the blood or urine of patients, are associated with activity of lupus and a related illness called primary Sjogren’s syndrome. Specific associations of BAFF and other molecules were found with lupus manifestations involving kidney, joints, skin or brain. Ethnicity appears to influence some of these associations. Combining measurement of molecules may help selecting patients who may benefit from belimumab, or define new molecule(s) to target.
USE - Centered Design: Integrating the User, Instrument, and Goal

Integrating the User, Instrument, and Goal SECENTERED DESIGN? This is not a typographical error but an appeal to human factors professionals to move toward more complete integration of human factors with other design factors. Although user-centered design has been an essential tool for advocating the need to consider the human factors in system design, it is off target. Removing the r from user is not equivalent to removing the "user" from our considerations. In fact, we argue that removing the r will lead to a more complete integration of human factors with other design factors. The position that we pre• • • • • • • • • • • •• sent here is not a radically DES I G N novel one; it has been central to human factors (e.g., Taylor, 1957) and to functional approaches in psychology (Brunswik, 1956; Dewey, 1896; Gibson, 1966; 1979). Although advocates for usecentered design can be found, it still represents a minority position within the human factors literature. The concept of user singles out the so-called human factor as a special, distinct component within the system. However, few would argue with the claim that system design is an integrative process that spans human and environment. Norman and Draper (1986) acknowledge this in the preface of their seminal volume User-Centered System Design: "to understand successful design requires understanding of the technology, the person, and their mutual interaction" (p. 1). The concept of use may be better suited to the demand for integration. Use implies a goal (used for what? ). • • • • • • inextricably machine as
Can Blogs promote fair and equitable teamwork

Abstract Online collaboration tools can provide an opportunity to enhance community building while at the same time motivate students to actively participate in their learning. In this investigation an online learning environment was designed with the aim of promoting clear and transparent communication between higher education students to enable fair and equitable teamwork. The environment was designed with a combination of authentic project work, self-regulated tasks and reflective activity through the use of Bloggers. An evaluation of the learning environment was conducted through both qualitative and quantitative survey instruments. Introduction Pedagogies adopted at university sometimes operate within a ﬁtransmissive paradigmﬂ, emphasising the transfer of knowledge from teacher to student. This approach is not conducive to experiential, active learning where students take a pro-active role in questioning, sharing ideas and applying prior knowledge to develop new ideas. More recently however, the increased emphasis on generic transferable skills has required a reframing and rethinking of teaching practices to obtain desired learning outcomes (Biggs, 1999). In the investigation reported here, activities were designed so that student teams were required to share the workload, undertake separate tasks and maintain tight deadlines and schedules from one week to the next. These activities were designed to be authentic, self-regulated and reflective in nature, and demanded students to consider requirements of others, be adaptive, responsible and flexible. However, within this team-based context, students often complain about unfair assessment. Some work harder than others, yet usually the whole team is given the same mark. Many students finish the unit feeling unsatisfied with the result, and weary of teamwork, and the assessment methods used to distribute marks. The aim of this study was to help solve this problem, as well as making the unit a valuable learning experience. A review of the literature is firstly conducted to support the design of learning environment, which uses a combination of student contracts, self assessment, reflective reports and tutor led peer assessment sessions to help make the teamwork rewarding, as well as being fair and equitable. It was also hoped that the learning environment would enable students to develop social, collaborative, professional and communicative skills, as well as actively engaging them in learning.
Transformerless three-phase on-line UPS with high performance

A transformerless three-phase on-line uninterruptible power supply (UPS) is proposed. The proposed UPS is composed of a rectifier, an inverter and a battery charger/discharger. The rectifier regulates a DC-link voltage and performs power factor correction. On the other hand, the inverter provides a regulated sinusoidal output voltage and has the current-limiting capability for an impulsive load. The battery charger/discharger reduces the number of battery and supplies the power demanded by the load in the event of the input power failure or abrupt decrease of the input voltage. Since both neutral lines of the input and output voltages are connected at the centre of the DC-link, the need for an isolation transformer is eliminated and the size, weight and cost of the system are significantly reduced. Additionally, new control algorithms of the rectifier, the charger/discharger and the inverter are proposed.
Health and safety gateways for construction project planning

Purpose – This paper aims to report on the findings from a research project, commissioned by the UK Health and Safety Executive (HSE), investigating the integration of health and safety (H&S) with construction planning.Design/methodology/approach – A combination of group and individual interviews were undertaken with qualitative methods of analysis to develop an integrated process model.Findings – The model developed uses “Gateway” decision points, which allows flexibility and the early integration of H&S at a strategic level, although detailed planning is still required through the use of integrated management tools.Practical implications – This study will help practitioners who wish to integrate CDM principles using a process model. It has also informed the HSE with policy decisions for their review of the Construction Design and Management Regulations 1994.Originality/value – Previous research on construction H&S has tended to concentrate on site management. This study extends knowledge and understandi.