Miracle-dz/UniFAR-FTUs huggingface dataset:
The Polycomb group gene Ezh 2 prevents hematopoietic stem cell exhaustion

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Microfossil-based biostratigraphy of the Precambrian Hecla Hoek sequence, Nordaustlandet, Svalbard

Summary The Precambrian Murchisonfjorden Supergroup of Nordaustlandet, Svalbard, contains approximately 6000 m of folded, but essentially unmetamorphosed, shallow marine sedimentary rocks. The abundant microfossils found through much of the section allow confident biostratigraphic subdivision of the succession and correlation with contemporaneous sequences in East Greenland and Scandinavia. Diamictite-bearing rocks of the Gotia Group (uppermost in the sequence) contain a depauperate assemblage of acritarchs dominated by Bavlinella Javeolata. A Vendian age of deposition is indicated. Carbonates of the immediately underlying Ryssö Formation contain a wide variety of microfossils including stromatolitic associations of several types, planktonic acritarchs, and, near the top of the formation, vase-shaped heterotrophic protists. The acritarchs, including Chuaria circularis, Kildinella hyperboreica, K. sinica, Trachysphaeridium spp. , and others, and the protistan remains indicate a latest Riphean age. The underlying Hunnberg Formation is similarly fossiliferous. A typically Late Riphean acritarch suite is present, and in addition double-walled forms and large (500 μm), thick-walled spheroids bearing club-shaped 10 μm diameter spines are found. Thus, it appears that the entire carbonate sequence of the Roaldtoppen Group was deposited late in Late Riphean time. The thick detrital succession comprising the lowermost part of the unmetamorphosed Nordaustlandet sequence, the Celsiusberget and Franklinsundet groups, contains fossils at various levels. Although microfossils are often somewhat coalified, identifiable Late Riphean taxa such as Chuaria circularis and Kildinella spp. are present in rocks as low as the middle Westmanbukta Formation. The presence of the distinctive carbonaceous macrofossil Tawuia dalensis in the Kapp Lord Formation permits an age estimate of 850–900 Ma for this formation. All told, the entire Murchisonfjorden Supergroup of Nordaustlandet appears to have been deposited during the Late Riphean and Vendian intervals. The long-recognized lithostratigraphic parallels between this sequence and the Eleonore Bay and Tillite Groups of East Greenland are complemented by strong biostratigraphic similarities.
Medical treatment and long‐term survival in a prospective study of 84 patients with endocrine pancreatic tumors

A prospective study was performed on 84 patients with neuroendocrine pancreatic tumors. Fifty‐nine (70%) had malignant tumors and received causal medical treatment. Streptozotocin in combination with 5‐fluorouracil or doxorubicin was used as first‐line treatment and produced overall objective responses in 20 of 44 (45%) patients with a median duration of response of 27.5 months. Thirty‐two patients who failed on chemotherapy subsequently received interferon treatment and 20 (63%) responded objectively with a median duration of 20.5 months. Octreotide, third‐line treatment in 14 patients, produced objective responses in four patients (28%) (median duration of response, 16 months). The median survival from diagnosis in malignant cases was 6.7 years. Even if none of the current medical therapies are curative for patients with malignant endocrine pancreatic tumors, a prolonged survival would be observed during the last decade. Since the age at diagnosis has not been dramatically reduced despite improvements in diagnostic methods, the prolonged survival might be attributed to causal medical treatment. Cancer 65:1883‐1890, 1990.
Investing in Engineering Student Leaders Through Industrial and STEM Partnerships

Students, universities, and industry are all struggling during these economically-challenging times. Students face rising tuition costs, universities face a reduction of state funding, and industry has a looming shortage of future technical leaders. Creating industrial and government partnerships to support the development of America’s future technical leaders has become imperative. The Southern Illinois University Carbondale’s (SIUC) Leadership Development Program (LDP) meets many of these pressing problems. The LDP has received more than $1 million from corporate sponsors and the National Science Foundation’s (NSF) Science, Technology, Engineering, and Mathematics (STEM) program to attract and develop engineering technical leaders. The university strives to graduate community-college-degreed transfer students within two and one half-years in an engineering leadership program.
Correlations between the Cross-Sectional Area and Moment Arm Length of the Erector Spinae Muscle and the Thickness of the Psoas Major Muscle as Measured by MRI and the Body Mass Index in Lumbar Degenerative Kyphosis Patients

Purpose: Lumbar degenerative kyphosis (LDK) is a subgroup of the flatback syndrome, which is a condition caused by spinal degeneration. LDK is reported to be the most frequent cause of lumbar spine deformity in the farming districts of the ‘oriental’ countries. We investigated the relationship between the cross-sectional area (CSA) and the moment arm length (MAL) of the erector spinae muscle and the thickness of the psoas major muscle (PT) and the body mass index (BMI) by performing statistical analysis, and we tried to show the crucial role of these variables for diagnosing LDK. Materials and Methods: From July 2004 to April 2005, we retrospectively reviewed 17 LDK patients who had undergone anterior lumbar interbody fusion (ALIF) with posterior stabilization. We measured both the CSA & MAL on the transverse cross-sectional MR image of the trunk at the fourth to fifth vertebrae (L4/5). The MAL was defined as the anterior-posterior distance between the center of the erector spinae muscle and that of the vertebral body. A comparative study was undertaken between the LDK group and the matched (according to age & gender) control group with regard to the CSA, MAL, PT and BMI. Results: The 17 LDK patients were all females [age: 62.5±4.93 years, height: 157±6.19 cm, weight: 55.59±4.7 kg, and BMI: 22.58±2.08 kg/m 2 ]. The control group patients were all females [age: 63.6±2.27 years, height: 156±5.05 cm, weight: 59.65±7.39 kg and BMI: 24.38 ±2.94 kg/m 2 ]. Spearman’s rho indicated a positive association between the CSA & BMI (rho=0.49, p=0.046), between the MAL & BMI (rho=0.808, p=0.000) and between the CSA & PT (rho=0.566, p=0.018) in the LDK patients. In terms of the CSA versus MAL, there was a positive association in both groups (rho=0.67, p=0.000, MAL=0.023CSA+5.454 in the LDK group; rho=0.564, p=0.018, MAL=0.02CSA+5.832 in the control group with using linear regression analysis). Independent t-tests revealed that both groups had statistically different mean values (p=0.000) in terms of the CSA & MAL. Conclusion: This study showed that the patients with LDK not only had atrophied erector spinae muscles, but also atrophied psoas major muscles and short MALs, which is harmful because of the increased lower back load in the aged patients. Along with BMI, measurement of the CSA, MAL & PT on the MR images provides an objective assessment of the dimension & severity of the muscle atrophy in the LDK patients.
Man, a Geomorphological Agent: An Introduction to Anthropic Geomorphology

Even the cost of a publication man a geomorphological agent an introduction to anthropic geomorphology by d nir%0D is so economical; lots of people are actually stingy to establish aside their cash to acquire guides. The other factors are that they really feel bad and also have no time to head to guide shop to browse guide man a geomorphological agent an introduction to anthropic geomorphology by d nir%0D to read. Well, this is contemporary era; many books could be got conveniently. As this man a geomorphological agent an introduction to anthropic geomorphology by d nir%0D as well as more publications, they could be entered really fast methods. You will certainly not have to go outside to obtain this book man a geomorphological agent an introduction to anthropic geomorphology by d nir%0D
Virulence and Antimicrobial Resistance Profiling of Salmonella Serovars Recovered from Retail Poultry Offal in KwaZulu-Natal Province, South Africa

As poultry organ meat is widely consumed, especially in low- and middle-income countries, there is reason to investigate it as a source of Salmonella infections in humans. Consequently, the aim of this study was to determine the prevalence, serotypes, virulence factors and antimicrobial resistance of Salmonella isolated from chicken offal from retail outlets in KwaZulu-Natal, South Africa. Samples (n = 446) were cultured for the detection of Salmonella using ISO 6579-1:2017. Presumptive Salmonella were confirmed using matrix-assisted laser desorption ionisation time-of-flight mass spectrometry. Salmonella isolates were serotyped using the Kauffmann–White–Le Minor scheme and antimicrobial susceptibility was determined by the Kirby–Bauer disk diffusion technique. A conventional PCR was used for the detection of Salmonella invA, agfA, lpfA and sivH virulence genes. Of the 446 offal samples, 13 tested positive for Salmonella (2.91%; CI = 1.6–5). The serovars included S. Enteritidis (n = 3/13), S. Mbandaka (n = 1/13), S. Infantis (n = 3/13), S. Heidelberg (n = 5/13) and S. Typhimurium (n = 1/13). Antimicrobial resistance against amoxicillin, kanamycin, chloramphenicol and oxytetracycline was found only in S. Typhimurium and S. Mbandaka. All 13 Salmonella isolates harboured invA, agfA, lpfA and sivH virulence genes. The results show low Salmonella prevalence from chicken offal. However, most serovars are known zoonotic pathogens, and multi-drug resistance was observed in some isolates. Consequently, chicken offal products need to be treated with caution to avoid zoonotic Salmonella infections.
Spectral Angle Minimization for the Retrieval of Optically Active Seawater Constituents from MODIS Data

The application of global algorithms to optical satellite imagery often fails to correctly assess the concentrations of seawater constituents (chlorophyll, CHL, suspended sediments, SS, and yellow substance, YS) in spectrally complex marine environments. Additional problems may come from inaccurate radiometric, atmospheric, and geometric corrections of the remotely sensed imagery. This issue is currently analyzed using a data set of seawater samples and MODIS images taken in the Tuscany Sea (Central Italy). The analysis demonstrates that the mentioned problems mainly introduce amplitude variations in the measured reflectance. This may have negative effects on the outcome of inversion algorithms based on the minimization of conventional spectral errors. Such effects can be notably reduced by using an error index derived from the angle between measured and simulated reflectance vectors, which is insensitive to spectral amplitude variations. The potential of a classical and the new error indices is first evaluated by regressing their values against concentration differences of optically active constituents found over the available sample pairs. The performance of the two error indices are then assessed within an inversion algorithms applied to the same samples. The results obtained show the potential of the new error index particularly to improve the estimation of CHL concentration.
Dialogic Reading

Dialogic reading is an evidence-based practice for preschool children who are typically developing or at-risk; yet there is limited research to evaluate if it has similar positive effects on the language and preliteracy skills of children with disabilities. This quasi-experimental study examined the effects of dialogic reading, with the incorporation of pause time, on the language and preliteracy skills of 42 preschool children with disabilities. Following random assignment of students at the classroom level, participants were equally distributed into an intervention (n = 21) and a comparison group (n = 21). Children received either dialogic reading or typical storybook reading for 10 to 15 min per day, 3 days per week, for 6 weeks. Children in the intervention group scored significantly higher on receptive and expressive near-transfer vocabulary assessments. This occurred both for words that were specifically targeted during dialogic reading, and for additional vocabulary words in the storybook.
Perception and reality: assessing priorities for sustainable development in the Niger River delta

The Niger Delta is the richest part of Nigeria in terms of natural resources. The area has large oil and gas deposits, as well as extensive forests, good agricultural land and abundant fish resources. Despite the tremendous natural and human resource base, the region's potential for sustainable development remains unfulfilled and its future is being threatened by environmental degradation and deteriorating economic conditions which are not being addressed by present policies and actions. Twenty-five years of oil development have not brought significant benefits to the region. Resource-use decisions are being driven by a lack of development, poor health, stagnant agricultural productivity, very limited opportunities in urban areas, rapid population growth, and tenuous property rights. The article attempts to advance beyond the prevailing emotive arguments on the causes of environmental degradation by examining the full range of environmental issues to determine priorities and to suggest options for sustainable development within an integrated coastal zone management framework.
Hydroclimatic changes in a climate‐sensitive tropical region

In this study, the hydroclimatic variables of Orissa, a tropical region in eastern India, and the cyclonic disturbances over the Bay of Bengal were analysed to assess trends and variations using nonparametric statistical procedures. The trend results revealed pronounced warming pattern in the monthly maximum temperatures and cooling pattern in the monthly minimum temperatures for the period 1987–2001. The differential forcing mechanisms of greenhouse gases and aerosols were considered as a reason for the temperature extremes. For the period 1960–2003, significant upward shift was observed in June rainfall, particularly over the region where orography influences the rainfall. This study provides strong evidence suggesting the occurrence of abrupt shifts in the cyclonic disturbances over the Bay of Bengal. For the period 1901–2003, the monsoon depressions and cyclonic storms, which contribute a substantial amount of rainfall in Orissa and central India, exhibited significant downward abrupt shifts during 1971 and 1950, respectively. However, severe cyclonic storms in the post‐monsoon season showed significant upward shift during the 1961–1965 pentad. More cases of non‐significant decreasing trends were observed in the monsoon rainfall for the period 1980–2003 in spite of high inter‐annual variability. These trends may be attributed to the significant downward shift in the monsoon depression from 1983 onwards analysed for the period 1960–2003. Results also show that the observed trends are highly sensitive to the season of analysis and the period of records. Copyright © 2012 Royal Meteorological Society
Factors Predicting Outcomes After Surgical Resection for Sporadic Cerebellar Hemangioblastomas

Hemangioblastomas are benign neoplasms of the central nervous system that often occur in the posterior fossa and especially in the cerebellar hemispheres (2). They manifest as highly vascular, solid, or cystic tumors. Hemangioblastomas of the brain may occur sporadically, but in about 20%e30% of cases, they are associated with von Hippel-Lindau (VHL) disease (14). Despite similar histologic characteristics, syndromic hemangioblastomas show systemic manifestations different from those of sporadic tumors. Hemangioblastomas associated with VHL disease may manifest with aggressive development through rapidly evolvingormultifocal lesionsandmayhavea strong effect on long-term patient outcomes (24). However, in some clinical studies, patients with sporadic hemangioblastomas and patients with hemangioblastomas associated with VHL disease are considered together as the sample (4, 20), and the studies specifically report the outcomes of syndromic hemangioblastomas (10, 14, 15, 17). In the present study, we retrospectively investigated the clinical and radiologic characteristics of patients who underwent surgical resection of sporadic cerebellar hemangioblastomas to determine the factors that can predict long-term outcomes.
Affect Acceptance by the Public of the Virtual Delivery of Public Services : The Effect of

Little is known about the determinants of acceptance by the general public of virtual delivery of governmental services. The authors conduct an empirical study of the factors that influence the willingness of individuals to consent to a para-authentic virtual experience with a public sector employee as part of the delivery of a public service. This study is based on the theory of social presence and on the unified theory of acceptance and use of technology (UTAUT). The authors test these hypotheses using 224 questionnaires completed by persons who have filed a police report using synchronous video-mediated communication (VMC). This multiple regression analysis shows that four variables are likely to predict willingness to use virtual interaction as a part of the delivery of a public service: performance expectations, social presence, social influence, and anxiety. Two findings were especially interesting. First, affective predictors, as opposed to cognitive predictors, were found to be of increasing importance for the acceptance by the public of virtual service delivery. Second, social presence emerged as the strongest affective predictor. This study’s empirical findings support the a priori assumption that affective predictors, as opposed to cognitive predictors, are relatively more important in predicting the intention to use virtual technologies, when contrasted with conventional technologies.
Stratigraphy and sedimentary environments of the Lower Cambrian Gog Group in the southern Rocky Mountains of Western Canada: Transgressive sandstones on a broad continental margin

Abstract The architecture, distribution and facies of sandstone bodies in the Gog Group of the southern Rocky Mountains of Western Canada record the dynamics of sand movement on the broad continental shelf of West Laurentia during the Early Cambrian phase of worldwide transgression. These sandstones represent early deposits of a passive margin under high rates of sediment supply; accommodation was sustained by high rates of thermal subsidence plus sea-level rise. This study focuses on the stratigraphy and sedimentology in the Bow Valley region, specifically the sector from Mount Assiniboine northwest to the North Saskatchewan River. The objectives are to: 1) revise the existing stratigraphic nomenclature; 2) provide a general facies description and paleoenvironmental analysis of the constituent units; and 3) place the depositional setting in the context of the evolution of the Western Canada Sedimentary Basin. The Gog Group in this area has historically comprised four units: the Fort Mountain Lake Louise, St. Piran and Peyto formations. North of Bow Pass, an additional unit, the Jasper Formation, occurs below the Fort Mountain Formation and is related to accommodation created by active rift-faulting during the latest Neoproterozoic. In the Lake Louise and Lake O’Hara area, four new formal subdivisions within the St. Piran Formation are proposed: Lake O’Hara, Lake Oesa, Lake Moraine and Wiwaxy Peaks members. A wide range of subenvironments is recognized. The Fort Mountain Formation and the uppermost part the Lake O’Hara and Moraine Lake members record shallow-subtidal sedimentation. The correlative interval at Mount Assiniboine appears to have been deposited closer to the source area, and paleocurrents reveal sediment transport towards the north, parallel to the shoreline. The Lake Louise Formation was deposited in a protected low-energy, inner-shelf setting, while most of the Lake O’Hara Member records inner-shelf compound dunes and sand sheets. The Lake Oesa Member, which erosively overlies the Lake O’Hara Member, represents deposition in a tidal-flat environment. It is capped by a transgressive shoreface consisting of the lowermost deposits of the Moraine Lake Member. A record of sedimentation in inner-shelf conditions dominates the middle part of this unit, but with facies indicative of deposition in shallow-subtidal conditions in the upper part. The Wiwaxy Peaks Member represents an inner-shelf sand-ridge complex, followed by development of a shoreface environment. The overlying limestone-dominated Peyto Formation records deposition on a carbonate ramp related to a decrease in siliciclastic sediment supply.
Metal dispersion and mobility in soils from the Lik Zn–Pb–Ag massive sulphide deposit, NW Alaska: environmental and exploration implications

The Lik deposit in northern Alaska is a largely unexposed shale-hosted Zn–Pb–Ag massive sulphide deposit that is underlain by continuous permafrost. Residual soils overlying the mineralized zone have element enrichments that are two to six times greater than baseline values. The most prominent elements are Ag, Mo, P, Se, Sr, V by total 4-acid digestion and Tl by a weak partial digestion (Enzyme Leach or EL) because they show multi-point anomalies that extend across the entire mineralized zone, concentration ranges are 0.5–2.6 ppm Ag, 4–26 ppm Mo, 0.1–0.3% P, 3–22 ppm Se, 90–230 ppm Sr, 170–406 ppm V, and 1.6–30 ppb Tl. Lead, Sb, and Hg are also anomalous (up to 178 ppm, 30 ppm, and 1.9 ppm, respectively), but all are characterized by single point anomalies directly over the mineralized zone, with only slightly elevated concentrations over the lower mineralized section. Zinc (total) has a consistent baseline response of 200 ppm, but it is not elevated in soils overlying the mineralized zone. However, Zn by EL shows a distinct single-point anomaly over the ore zone that suggests it was highly mobile and partly adsorbed on oxides or other secondary phases during weathering. In situ analyses (by laser ablation ICP-MS) of pyrite and sphalerite from drill core suggest that sphalerite is the primary residence for Ag, Cd, and Hg in addition to Zn, and pyrite contains As, Fe, Sb, and Tl. The level and degree of oxidation, and the proportion of reacting pyrite and carbonate minerals are two factors that affected the mobility and transport of metals. In oxidizing conditions, Zn is highly mobile relative to Hg and Ag, perhaps explaining the decoupling of Zn from the other sphalerite-hosted elements in the soils. Soils are acidic (to 3.9 pH) directly over the deposit due to the presence of acid-producing pyrite, but acid-neutralizing carbonate away from the mineralized zone yield soilsthat are near neutral. The soils therefore formed in a complex system involving oxidation and weathering (mechanical and chemical) of sulphide minerals, dissolution of carbonate minerals, and precipitation of iron and manganese oxide minerals.