Miracle-dz/UniFAR-FTUs huggingface dataset:
Perspective towards End-of-Life Care among Nurses Working in BPKIHS: A Cross-Sectional Study

Background: End-of-life care (EOLC) is the term used to describe the support and medical care given to dying patients and their families during the time surrounding death. It has a direct impact on the attitude of nurses towards the care of dying. We aimed to assess the perspective towards end-of-life care and its association with different socio-demographic variables among the nurses working in B.P. Koirala Institute of Health Sciences (BPKIHS). Methods: This cross-sectional study was carried out among 136 nurses working in the selected settings of BPKIHS. Simple random sampling was used to select staff nurses and purposive sampling to select senior staff nurses and senior Auxiliary Nurse Midwifes. Frommelt Attitude towards Care of the Dying (FATCOD-B) scale was used to assess the nurses' perspective towards care of dying. Data were analyzed using SPSS version 17.0. Descriptive statistics were used for describing sample characteristics. The Chi-square test was used to show the association between level of attitude and socio-demographic variables. Results: Almost two-third (64%) of the nurses had a fair attitude, 36% had a good attitude. The socio-demographic characteristics i.e.; marital status, ward/unit, level of education, designation, total duration of work, experience of caring for dying, and training on end-of-life care were significantly associated with the nurses' attitude towards care of dying. Conclusion: Overall, nurses had a fair attitude towards the care of dying; none had a poor attitude.
A novel low‐density lipoprotein/fibrinogen apheresis method for chronic limb‐threatening ischemia in patients with poor options for revascularization: A multicenter, single‐arm clinical trial

Low‐density lipoprotein (LDL) apheresis is a treatment option for patients with unhealed chronic limb‐threatening ischemia (CLTI) after revascularization. The newly developed AS‐25 is a direct hemoperfusion‐type apheresis device that differs from conventional LDL apheresis therapy and is designed to specifically adsorb both LDL‐C and fibrinogen. We evaluate the efficacy and safety of AS‐25.
Ultrahigh Step-Up Quadratic Boost Converter Using Coupled Inductors With Low Voltage Stress on the Switches

In this article, a new ultrahigh step-up dc–dc converter is proposed. The circuit is composed of a quadratic boost converter (QBC), two coupled inductors (CIs), and a voltage multiplier cell. The distinguishing features of this converter are low voltage stress on the main power switches, continuity of the input current, common ground between load and source, and ultrahigh voltage gain. Among all the compared converters, voltage gain of the converter in the entire duty cycle and the CIs turn ratio range is higher and unique of its kind. A prototype is also prepared in order to experimentally validate feasibility and effectiveness of the proposed converter. This prototype is rated at 250 W and 600 V output power and voltage, respectively. In the experiments, the output voltage is controlled on its rated value of 600 V, while the input voltage varies from 15 to 30 V, meaning that the maximum experimental voltage gain is equal to 40.
HOW DO TRADE, INFLATION, EXCHANGE RATES, AND INFORMATION TECHNOLOGY INFLUENCE INTERNATIONAL TOURIST VISITS IN INDONESIA?

This study aims to determine the short-term and long-term effects of trade, inflation, exchange rates, and information technology on international tourist visits in Indonesia. This study uses a quantitative approach within the Vector Error Correction Model (VECM) technique. The data used in this study are annual time series data of Indonesia trade, inflation, exchange rate and information technology on 1991-2019 period. The data used in this study were sourced from World Bank, International Monetary Fund (IMF), and Central Statistics Agency data. The results of the VECM research in the short term show that the variables of trade and information technology have a significant positive effect on international tourist visits. Meanwhile, inflation and exchange rates have a significant negative effect on international tourist visits. Then the results of VECM research in the long term show that variables of trade and information technology have a significant positive effect on international tourist visits. Meanwhile, inflation has a significant negative effect on international tourist visits. This study bring any literature contribution to future study that macroeconomics variables (trade, inflation) and information technology can influence the rise and fall of tourist visits to Indonesia. Practical contributions also brougt by this study as recommendations to increase international tourist visit in Indonesia for government and tourism stakeholder.
The theory of partial differential equations

Preface 1. Fourier series and Fourier transforms 2. Distributions 3. Elliptic equations (fundamental theory) 4. Initial value problems (Cauchy problems) 5. Evolution equations 6. Hyperbolic equations 7. Semi-linear hyperbolic equations 8. Green's functions and spectra Supplementary remarks Guide to the literature Bibliography Symbols Index.
Immunogenicity and Safety of mRNA Anti-SARS-CoV-2 Vaccines in Patients with Systemic Lupus Erythematosus

Vaccination is the most effective preventive measure to control the spread of COVID-19 and reduce associated complications. This study aims to evaluate the efficacy and safety of mRNA COVID-19 vaccines in patients with systemic lupus erythematosus (SLE). A total of 41 adult SLE patients receiving two doses of the SARS-CoV-2 mRNA Comirnaty-BioNTech/Pfizer vaccine were enrolled. The quantitative determination of anti-trimeric spike protein-specific IgG antibodies to SARS-CoV-2 was assessed before (T0), 21 days after the administration of the first dose of the vaccine (T1), and between 21 and 28 days after the second dose (T2). They were compared with the same determinations from a cohort of 29 patients with C1-esterase inhibitor deficiency hereditary angioedema (C1-INH-HAE) as controls. All the SLE patients and controls demonstrated a positive serological response after a single dose of the vaccine (T1), which significantly increased after the second dose (T2). No significant difference was found between SLE patients and controls at T1 [t(52.81) = −0.68; p = 0.49] and at T2 [t(67.74) = −0.22; p = 0.825]. Systemic Lupus Erythematosus Disease Activity Index (SLEDAI) analysis showed that the vaccine did not influence SLE activity or caused disease flare in our cohort. In conclusion, COVID-19 vaccines produced a satisfactory response in SLE patients without variation in the disease activity.
Unfolding the conductivity reversal n- to p-type in phosphorus-doped ZnO thin films by spin-on dopant (SOD) process

Phosphorus doping induced p-type doping in ZnO thin films based on spin-on dopant (SOD) process is reported in this article. Owing to the reduced dependence on the conventional amenities for diffusion/ion-implantation doping, the SOD process provides a simple and cheap doping method. The effect of SOD process temperature on conductivity ZnO thin films is investigated by altering the temperature from 700°C to 1000°C. Systematic field emission scanning electron microscopy analysis demonstrates the impact of doping temperature on the morphological properties of SOD. The x-ray diffraction measurements reveal that the p-type ZnO thin films had (002) preferred crystal orientation. At the same time, x-ray photoelectron spectroscopy validated the formation of the PZn–2VZn complex, which was responsible for the acceptor behaviour of films. Moreover, the photoluminescence spectra tracked down that the origin of 3.35 and 3.31 eV emission peaks is due to the acceptor bound exciton and free-electron to acceptor level transitions, respectively. Finally, an elevated hole concentration of 2.09 × 1016 cm−3 is achieved with a resistivity of 1.14 Ω-cm at 800°C doping temperature. However, the film doped at 900°C and 1000°C showed n-type behaviour due to the generation of high concentration donor defects. Here, we successfully demonstrate that the SOD process has great potential to produce high-quality p-type ZnO thin films suitable for optoelectronic devices applications.
MAXIMUM LIKELIHOOD AND BAYESIAN METHODS FOR MIXTURES OF NORMAL DISTRIBUTIONS

MAXIMUM LIKELIHOOD AND BAYESIAN METHODS FOR MIXTURES OF NORMAL DISTRIBUTIONS. Peter M. Saama. UCLA Office of Academic Computing. November, 1997. A. ABSTRACT Data were waiting times between eruptions of the Old Faithful geyser in Yellowstone National Park, Wyoming, USA. The sample histogram showed evidence of bimodality. Forthwith, a twocomponent normal mixture model was fitted to the data. The Gauss-Newton algorithm was used to obtain the maximum likelihood estimate of the nuisance parameters in the mixture model. An alternative method which uses the Gibbs Sampler to obtain parameter estimates as well as 100(1FUHGLEOH EDQGV IRU WKH SDUDPHWHUV ZDV LPSOHPHQWHG DQG LV SUHVHQWHG B. INTRODUCTION Because of overdispersion and heterogeneity in the population, a mixture of distributions is often used to model the quantitative response. Such distributions are often considered appropriate models for thought to consist of a number of relatively distinct sub-populations (c). In situations where the number of components is unknown, mixture densities of the form ( ) ∑ = k
Evolutionary Conservation of PP2A Antagonism and G2/M Cell Cycle Arrest in Maedi-Visna Virus Vif

The canonical function of lentiviral Vif proteins is to counteract the mutagenic potential of APOBEC3 antiviral restriction factors. However, recent studies have discovered that Vif proteins from diverse HIV-1 and simian immunodeficiency virus (SIV) isolates degrade cellular B56 phosphoregulators to remodel the host phosphoproteome and induce G2/M cell cycle arrest. Here, we evaluate the conservation of this activity among non-primate lentiviral Vif proteins using fluorescence-based degradation assays and demonstrate that maedi-visna virus (MVV) Vif efficiently degrades all five B56 family members. Testing an extensive panel of single amino acid substitution mutants revealed that MVV Vif recognizes B56 proteins through a conserved network of electrostatic interactions. Furthermore, experiments using genetic and pharmacologic approaches demonstrate that degradation of B56 proteins requires the cellular cofactor cyclophilin A. Lastly, MVV Vif-mediated depletion of B56 proteins induces a potent G2/M cell cycle arrest phenotype. Therefore, remodeling of the cellular phosphoproteome and induction of G2/M cell cycle arrest are ancient and conserved functions of lentiviral Vif proteins, which suggests that they are advantageous for lentiviral pathogenesis.
The Wasserstein geometry of nonlinear σ models and the Hamilton–Perelman Ricci flow

Nonlinear sigma models are quantum field theories describing, in the large deviation sense, random fluctuations of harmonic maps between a Riemann surface and a Riemannian manifold. Via their formal renormalization group analysis, they provide a framework for possible generalizations of the Hamilton–Perelman Ricci flow. By exploiting the heat kernel embedding introduced by Gigli and Mantegazza, we show that the Wasserstein geometry of the space of probability measures over Riemannian metric measure spaces provides a natural setting for discussing the relation between nonlinear sigma models and Ricci flow theory. In particular, we analyze the embedding of Ricci flow into a heat kernel renormalization group flow for dilatonic nonlinear sigma models, and characterize a non-trivial generalization of the Hamilton–Perelman version of the Ricci flow. We discuss in detail the monotonicity and gradient flow properties of this extended flow.
Blubber cortisol in four Canadian beluga whale populations is unrelated to diet

: Changing conditions in the Arctic have had severe consequences for many marine mammals. In this study, we examined blubber cortisol using radioimmunoassay in 4 Canadian beluga whale Dephinapterus leucas populations. The endangered Cumberland Sound population had higher cortisol levels (mean ± SE: 0.65 ± 0.11 ng g −1 ) than populations not at risk: Eastern Beaufort Sea (0.31 ± 0.03 ng g −1 ; p < 0.001), Eastern High Arctic-Baffin Bay (0.32 ± 0.09 ng g −1 ; p = 0.004), and Western Hudson Bay (0.44 ± 0.04 ng g −1 ; p = 0.004). To evaluate if measured cortisol differences were due to differences in diet, we compared stable isotope ratios of carbon and nitrogen ( δ 13 C and δ 15 N) and dietary fatty acids among populations. Beluga whales from Eastern Beau-fort Sea had lower δ 13 C (p ≤ 0.017) and higher δ 15 N (p < 0.001) values than other measured populations, while Western Hudson Bay beluga dietary fatty acid profiles differed from other measured populations (p < 0.001). Population and sex were significant predictors of blubber cortisol (p ≤ 0.017). Females exhibited higher cortisol than males. Despite diet differences among populations, neither stable isotopes nor fatty acids were significant predictors of cortisol, suggesting differences in cortisol levels were unrelated to diet. Other factors, such as increased risk of predation, hunting pressure, vessel traffic, or differences in baseline blubber cortisol concentrations may be contributing to elevated cortisol levels in Cumberland Sound beluga whales. Measuring blubber cortisol in combination with chemical indicators of diet provides a useful method for monitoring population health and can be used to inform management and conservation.
Moving target detection in over‐the‐horizon radar using adaptive chirplet transform

In over‐the‐horizon radar (OTHR) moving target detection, the signal to clutter ratio (SCR) is low for slow targets near the clutter, such as ships. One method to detect a moving target is to first reject the clutter and improve the SCR before the detection, such as the adaptive Fourier transform developed by Root [1998a , 1998b , 1998c] when a target moves uniformly. When a target does not move uniformly, the Fourier‐based techniques for the target detection including superresolution techniques may not work well. In this paper, we propose an adaptive chirplet transform technique in the Doppler processing in OTHR as an alternative of the Fourier transform technique when a target moves nonuniformly.
Classroom-based language assessment literacy and professional development need between novice and experienced EFL teachers

Classroom-based language assessment (CBLA) in the Indonesian context has become more significant since the shift of the assessment model from summative based assessment (Ujian Nasional or the final exam) to formative-based assessment (Asesmen Kompetensi Minimum (AKM); therefore, teachers need to develop their classroom-based language assessment literacy (CBLAL). The model places a greater emphasis on students' learning outcomes in class rather than final test scores. This study aims to examine the CBLAL level of experienced and novice EFL teachers, their perceptions of CBLAL, and their needs for CBLAL training. Quantitative and qualitative data were used in conjunction with a case study research design. The CBLAL questionnaire, adopted from Lan and Fan's work (2019), collected quantitative data from 55 EFL teachers. Meanwhile, the qualitative data were collected from four of them (novice and experienced) in the interview sessions. The CBLAL levels of 55 teachers are between functional and procedural-conceptual literacy levels. Both experienced (ETs) and novice teachers (NTs) could grasp fundamental principles in language assessment and can use them in the classroom. Although the ETs have higher levels, there is no significant difference in CBLAL levels between ETs and NTs. The study also revealed that the teachers' understandings of technical skills and language pedagogy were among the highest compared to their knowledge of theories and principles on language assessments. However, they indicated that still require professional development (PD) in CBLAL, despite their functional and procedural-conceptual literacy. The current study has pedagogical implications for both ETs and NTs. They should actively participate in various professional development activities, focusing on classroom evaluation.
Fermi-LAT sensitivity and constraints on dark matter signal from the Milky Way host halo and its substructure

Author(s): Anderson, Brandon | Advisor(s): Johnson, Robert R | Abstract: Despite overwhelming evidence of its existence, the exact nature of Dark Matter (DM) remains unknown. Theoretically well-motivated, Weakly Interacting Massive Particles (WIMPs) make strong candidates for fullling the DM role; they provide gravitationalforce without participating in the electromagnetic interactions that would make them conventionally visible. Even so, their weak interactions en masse could allow them annihilate or decay into substantial quantities of visible particles, including gamma rays. Continuing observations from the Fermi Large Area Telescope (LAT) provide an opportunity to detect or rule out this possibility. Powerful modern N-body simulations like Via Lactea II make predictions for the distribution and consequent signal of Milky Way (MW) DM substructure for a given WIMP model. Without the fortuitous placement of nearby DM, however, detecting annihilation from a clump would be difficult. Indeed none have yet been conclusively observed. The much larger Host Halo, in whose gravity well the MW resides, constitutes a much more reliable source of possible DM gamma rays. This signal competes with the complex and uncertain background produced by cosmic-ray interactions in the MW medium. A search for DM Host Halo photons including these background systematics gives constraints on the nature of the DM WIMP.
Hydrometeorological analysis of a flash flood event in an ungauged Mediterranean watershed under an operational forecasting and monitoring context

The current study presents the first attempt to investigate the November 2019 catastrophic flash flood in Olympiada (North Greece) under an operational forecasting and monitoring context, based on the mesoscale weather and research forecasting (WRF) model and the integrated multi‐satellite retrievals for global precipitation measurement (GPM‐IMERG) algorithm. When evaluated against ground‐based rainfall measurements, WRF showed an adequate predictive capability concerning the severity of the observed rainfall, even though the model's performance suffered from phase and spatial displacement errors. The GPM‐IMERG algorithm yielded the best performance in capturing the timing of the observed excessive rainfall. Concerning the hydrological outcome using the Hydrologic Engineering Center‐Hydrologic Modelling System (HEC‐HMS), a strong indication of the forthcoming flash flood could have been provided at least 2 days in advance based on the WRF‐based HEC‐HMS‐simulated flood peak (139.3 m3 s−1), as it was close to the drainage capacity of a constructed bridge in the plain stream bed, and to the 100‐year return period flood discharge.
Pretreatment with Low-Dose Esketamine for Reduction of Propofol Injection Pain: A Randomized Controlled Trial

Background Propofol-induced injection pain is a common adverse effect during the induction of general anesthesia. The purpose of this study is to investigate the effect of low-dose esketamine in preventing propofol injection pain. Methods In this double-blind, randomized, controlled trial, patients scheduled for elective ear surgery under general anesthesia received either normal saline (NS), or 40 mg lidocaine, or 0.15 mg/kg esketamine 30 seconds before manual injection of propofol. The primary outcome of this study was the incidence of propofol injection pain. The secondary outcomes included injection pain score, vital signs, total dosage of vasoactive drugs used within 5 minutes after induction, and adverse events related to drugs. Results A total of 105 patients were included. Compared with the NS group (67%), pretreatment with esketamine and lidocaine significantly reduced the incidence of injection pain to 29% and 33%, respectively (both P < 0.05); however, no significant difference was found between the esketamine and lidocaine groups. The median of injection pain score was significantly lower in the esketamine and lidocaine groups (both median (interquartile range) = 0 (0–1)) than that in the NS group (1 (0–2); P < 0.05). In addition, compared with the NS and lidocaine groups, preinjection esketamine provided more stable hemodynamic parameters within 5 minutes after induction (P < 0.05). No statistical difference was found in adverse events among the three groups. Conclusions Pretreatment with a low-dose esketamine can not only reduce the incidence of propofol injection pain but also provide a more stable circulation in patients after anesthesia induction. This convenient, well-tolerated, and economic treatment appears as an option to be routinely applied in clinic practice. Clinical Trial Registration. This trial is registered with https://www.chictr. org.cn/showproj.aspx? proj=136690 (the number for the trial registration isChiCTR2100052742).
ECONOMIC JUSTICE AND THE SPIRIT OF ISLAMIC ECONOMICS: A REVIEW OF JOSEPH E. STIGLITZ AND MUHAMMAD YUNUS’ THOUGHTS ON ECONOMIC AND LAW

This paper aims to analyze the political discourse of economic law in the era of globalization in developing countries from the perspective of Joseph E. Stiglitz and Muhammad Yunus. The globalization has affected various sectors of people's lives, including the pattern of free markets that occur for all lower-middle-income countries, instead destroys them. Many economists who pay attention to this issue, include Joseph E. Stiglitz and Muhammad Yunus who have greatly influenced the global world regarding economic development. This qualitative research uses a comparative approach, and secondary data such as journal articles, books, and reports. Data were collected through documentation techniques and analyzed using interactive model analysis. The result indicates that the discourses of thought between Joseph E. Stiglitz and Muhammad Yunus about the politics of economic law have similarities and differences. The two economists agree that economics, law, and humanity have a very close connection. They recommended that efforts to reform mondial policies be carried out based on participation, equality, independence, justice and democracy. In addition, the effects of globalization in the economic sector need to be regulated fairly. Thus, their thoughts are in line to the basic principles of Islamic economics: principles of equilibrium and justice.
DETECTION OF C60 IN THE PROTOPLANETARY NEBULA IRAS 01005+7910

We report the first detection of buckminsterfullerene (C60) in a protoplanetary nebula. The vibrational transitions of C60 at 7.0, 17.4, and 18.9 μm are detected in the Spitzer/Infrared Spectrograph spectrum of IRAS 01005+7910. This detection suggests that fullerenes are formed shortly after the asymptotic giant branch but before the planetary nebulae stage. A comparison with the observations of C60 in other sources is made and the implication for circumstellar chemistry is discussed.
Communicating urgency through humor: School Strike 4 Climate protest placards

Protest placards are an important part of School Strike 4 Climate (SS4C) protest culture and illustrate how protesters view, understand and share their environmental concerns. Many of the placards use humor to convey the messages of their creators. Bringing together science communication and humor studies, this paper examines the communicative functions of humor in Australian SS4C posters by asking to what extent protest signs can be understood as a vehicle of science communication. The paper reveals how humorous protest placards become the means of grassroots creativity, exploring bottom-up science communication in an ambiguous, but accessible and enjoyable form.