Miracle-dz/UniFAR-FTUs huggingface dataset:
Relativistic tests with lunar laser ranging

This paper presents the recent version of the lunar laser ranging (LLR) analysis model at the Institut für Erdmessung (IfE), Leibniz Universität Hannover and highlights a few tests of Einstein’s theory of gravitation using LLR data. Investigations related to a possible temporal variation of the gravitational constant, the equivalence principle, the PPN parameters β and γ as well as the geodetic precession were carried out. The LLR analysis model was updated by gravitational effects of the Sun and planets with the Moon as extended body. The higher-order gravitational interaction between Earth and Moon as well as effects of the solid Earth tides on the lunar motion were refined. The basis for the modeled lunar rotation is now a 2-layer core/mantle model according to the DE430 ephemeris. The validity of Einstein’s theory was studied using this updated analysis model and an LLR data set from 1970 to January 2015. Within the estimated accuracies, no deviations from Einstein’s theory are detected. A relative temporal variation of the gravitational constant is estimated as G˙/G0=(7.1±7.6)×10−14 yr−1, the test of the equivalence principle gives Δ(mg/mi)EM=(−3±5)×10−14 and the Nordtvedt parameter η=(−0.2±1.1)×10−4, the PPN-parameters β and γ are determined as β−1=(−4.5±5.6)×10−5 and γ−1=(−1.2±1.2)×10−4 and the geodetic precession is confirmed within 0.09%. The results for selected relativistic parameters are obtained by introducing constraints from an LLR solution without estimating relativistic quantities. The station coordinates are constrained for the estimation of G˙/G0, β and γ, the initial value of the core rotation vector is constrained to a reasonable model value for the estimation of G˙/G0 and geodetic precession. A constrained z-component of the initial lunar velocity is used for the estimation of the geodetic precession.
INVESTORS’ OVERCONFIDENCE IN THE STOCK MARKET

An investor would normally depend on technical or/and fundamental analysis to make his/her investment decision in the secondary market. But in most cases the investor may not have time to do these analyses, understand the market or stock and then make the decision, therefore, they often end up taking irrational decisions. In some cases, the investors take these irrational decisions on the basis of the overconfidence they have concerning the information they possess. These investors are termed to bear overconfidence bias. The study aims to examine the influence of overconfidence bias in the Indian stock market. The study employed Vector Autoregression (VAR) methodology and impulse response function to know how long the bias persists in the market once the overconfidence bias is influenced by the investor. The results of the study show enough evidence to point out the influence of overconfidence bias in the market and it persists for more than 110 days. The study also finds out Efficient Market Hypothesis does not hold good. Our study period includes the time period since globalization of the Indian stock market and it also covers several periods of stress including the global financial crisis of 2007–08 and COVID-19 period.
Complications and risk factors of early-onset versus late-onset gestational diabetes mellitus

Objectives: To contribute to this discussion by comparing the complications associated with early-diagnosed versus (vs.) late-diagnosed gestational diabetes mellitus (GDM) for mothers and infants in order to provide baseline data that might guide future changes in the current recommendations for screening. Methods: The study compares the risk factors and complications for early- vs. late-diagnosed GDM in a cohort from Saudi Arabia. Prenatal, perinatal, postpartum, and neonatal variables were compared between the early vs. late-diagnosed GDM groups using information gathered from the patient’s hospital records. Results: Significant predictors of early-diagnosed GDM included pregestational BMI and GDM history. Additionally, early diagnosis of GDM was linked to a higher incidence of pre-eclampsia and intrauterine fetal death. Women with early-diagnosed GDM also required more glycemic control interventions, like administering insulin and metformin and controlling their diet. The fetal birth weight and postpartum BMI were significantly higher in the early onset GDM group. The need for insulin and pre-eclampsia were significant factors linked to an early diagnosis of GDM, according to a logistic regression analysis. Conclusion: Therefore, the current findings emphasize the need for early screening in pregnant women with high pregestational BMI and a history of GDM and show that those with early-onset GDM more likely to need insulin therapy and be at a higher risk of developing pre-eclampsia.
Medial Vowel Temporal Acoustics in Arabic and Japanese Polysyllabic Words

The current study is dedicated to measuring vowel temporal acoustics (duration, durational diﬀerence, and durational ratio) in the medial position of mostly CVCVCV polysyllabic words in Arabic and Japanese, avoiding the asymmetries in vowel position, syllable structure, and coda consonant quantity (singleton versus geminate) observed in previous experiments. Twenty-nine (16 Arabic and 13 Japanese) participants were asked to use a carrier sentence to produce 60 polysyllabic (mainly CVCVCV) items that contrasted in vowel quantity (short versus long) and vowel quality (/a/, /i/, and /u/) at a normal speech rate. The results show that while short and long vowels are durationally distinct within a language, Japanese vowels are clearly longer than Arabic vowels, although the durational diﬀerence remains approximately the same between the two languages. The durational ratio of short-to-long vowel presents a new pattern that contrasts with that reported in earlier research. Speciﬁcally, Japanese long vowels in the medial position of polysyllabic words are twice as long as their short counterparts, while Arabic long vowels are more than twice as long. This shows that both vowel position and syllable structure must be considered when measuring vowel temporal acoustics or when structuring stimuli for perception experiments.
Sex differences in intuitive eating and its relationship with body mass index among adults aged 18–40 years in Saudi Arabia: a cross-sectional study

Introduction Intuitive eating (IE) is eating without judgment, relying only on physiological hunger and satiety. Sex differences in IE have been reported; however, none of the studies have explicitly examined IE and its relationship with body mass index (BMI) in the Saudi Arabian population. Thus, this study aimed to investigate sex differences in IE and its relationship with BMI in the Saudi population. Subjects/methods A cross-sectional online survey of 360 participants (18 years or older) with self-reported weight and height was conducted. IE was measured using the Intuitive Eating Scale-2 (IES-2). Separate multiple linear regression analyses were conducted to determine if total IE and its subscale scores differed across sexes. It was also conducted to assess the relationship between IE and BMI across sexes. Results Women had higher total IE score, eating for physical rather than emotional reasons (EPR), and body-food choice congruence (BFCC) scores compared to men (p = 0.013, p = 0.01, p <0.001, respectively). The analysis showed a significant negative association between total IE, BFCC, EPR scores, and BMI in women compared to men (p = 0.023, p = 0.01, p = 0.003, respectively). Conclusion The data on the sex differences in IE and its subscales and their different association with BMI encourage tailing nutrition-related recommendations in the context of intuitive eating based on sexes. Future studies are needed to explore how intuitive eating functions differently in women compared to men and explore the causal relationship between IE and BMI in this population.
Creating inclusive schools to reduce health and well‐being disparities

In the U.S., people with marginalized racial/ethnic, social class, sexual, and gender identities often have worse physical and mental health than people with more privileged identities. This paper reviews psychological research suggesting that inclusive school cultures can improve the health and well-being of those with marginalized identities. Specifically, we review two examples of sets of ideas and practices in schools that create more supportive environments: (a) ideas and practices that recognize and include diverse identities and (b) ideas and practices that support interdependent ways of thinking, feeling, and acting. We also speculate about the psychological and behavioral mechanisms by which each protects health and well-being, including reducing discrimination, increasing school belonging, strengthening positive ingroup identities, and allowing students to access culturally relevant support. We suggest that changing school cultures to make them more inclusive is one way to reduce health and well-being disparities.
Research on Coal Gangue Detection and Recognition Based on Lightweight Network MS-YOLOV3

multi-condition coal and gangue datasets were constructed. The model was trained and the identifi - cation and positioning results of the model were tested under different sizes, illumination intensities and various working conditions, and compared with other algorithms. Experimental results show that the proposed algorithm can detect the coal gangue quickly and accurately, with an mAP of 99.08%, a speed of 139 fps and a memory occupation of only 9.2 M. In addition, the algorithm can effectively detect mutually stacking coal and gangue of different quantities and sizes under different lights with high confidence and with a certain degree of environmental robustness and practicability. Compared with the YOLOv3, the performance of the proposed algorithm is significantly improved. Under the premise that the accuracy is unchanged, the fPS increases by 127.9% and the memory decreases by 96.2%. Therefore, the MS-yOLOv3 algorithm has the advantages of small memory, high accuracy and fast speed, which can provide online technical support for the detection and identification of coal and gangue
Regulation of cellular contractile force, shape and migration of fibroblasts by oncogenes and Histone deacetylase 6

The capacity of cells to adhere to, exert forces upon and migrate through their surrounding environment governs tissue regeneration and cancer metastasis. The role of the physical contractile forces that cells exert in this process, and the underlying molecular mechanisms are not fully understood. We, therefore, aimed to clarify if the extracellular forces that cells exert on their environment and/or the intracellular forces that deform the cell nucleus, and the link between these forces, are defective in transformed and invasive fibroblasts, and to indicate the underlying molecular mechanism of control. Confocal, Epifluorescence and Traction force microscopy, followed by computational analysis, showed an increased maximum contractile force that cells apply on their environment and a decreased intracellular force on the cell nucleus in the invasive fibroblasts, as compared to normal control cells. Loss of HDAC6 activity by tubacin-treatment and siRNA-mediated HDAC6 knockdown also reversed the reduced size and more circular shape and defective migration of the transformed and invasive cells to normal. However, only tubacin-mediated, and not siRNA knockdown reversed the increased force of the invasive cells on their surrounding environment to normal, with no effects on nuclear forces. We observed that the forces on the environment and the nucleus were weakly positively correlated, with the exception of HDAC6 siRNA-treated cells, in which the correlation was weakly negative. The transformed and invasive fibroblasts showed an increased number and smaller cell-matrix adhesions than control, and neither tubacin-treatment, nor HDAC6 knockdown reversed this phenotype to normal, but instead increased it further. This highlights the possibility that the control of contractile force requires separate functions of HDAC6, than the control of cell adhesions, spreading and shape. These data are consistent with the possibility that defective force-transduction from the extracellular environment to the nucleus contributes to metastasis, via a mechanism that depends upon HDAC6. To our knowledge, our findings present the first correlation between the cellular forces that deforms the surrounding environment and the nucleus in fibroblasts, and it expands our understanding of how cells generate contractile forces that contribute to cell invasion and metastasis.
KOREAN MUSIC AWARDS AND ABNORMAL STOCK RETURNS

The global success of the K-pop music industry impacts the investment climate of the entertainment industry in the South Korean stock market. One of the driving factors attracting investors is the awards obtained by the K-pop idols. Hence, this event study investigates whether idols’ receiving awards creates stock abnormal returns (ARs) and cumulative abnormal returns (CARs). We collected five-day stock price data surrounding the events from 2018 to 2019 for the four entertainment companies. Using mean difference tests, we analyzed the movements of the stock returns. Our results show the appearance of positive and negative ARs dan CARs, indicating that investors react differently to the information contained in award announcements. This implies a deviance from the efficient market hypothesis and that investors behave irrationally whom investment decision affects the market. For this reason, companies should select awards when involving their idols.
Assessment of the Health of Soils Contaminated with Ag, Bi, Tl, and Te by the Intensity of Microbiological Activity

Soil health is the basis of ecological and food security for humanity. Among the informative indicators of soil health are microbiological indicators based on the intensity of the carbon dioxide release from the soil. The reaction of the microbial community of Haplic Chernozem Loamic, Haplic Arenosols Eutric, and Haplic Cambisols Eutric to contamination with oxides and nitrates of Ag, Bi, Tl, and Te at doses of 0.5, 1, 3, 10, and 30 derived specific permissible concentrations (SPC) was analyzed in the conditions of a vegetation experiment (the exposure period was 10 days). One derived concentration is assumed to be equal to three background concentrations of the element in the soil. The carbon content of microbial biomass in Haplic Chernozem varied between the experimental options from 6 to 218 mg/kg of soil; in Haplic Arenosols, from 3 to 349 mg/kg of soil; and in Haplic Cambisols, from 7 to 294 mg/kg of soil. Microbial biomass was a more sensitive indicator of contamination by the studied pollutants than basal soil respiration. A decrease in specific microbial respiration was found when Haplic Cambisols were contaminated with Ag, Bi, Te, and Tl oxides. Te and Tl nitrates had a significant toxic effect on each type of soil. At the maximum dose of Tl and Te nitrate, a decrease in basal soil respiration of 56–96% relative to the control and an increase in the metabolic coefficient by 4–6 times was found. The toxicity series of heavy metals averaged for all types of soils in terms of microbiological activity was established: Bi > Ag > Te > Tl (oxides) and Te > Tl > Ag > Bi (nitrates). Nitrates of the elements were more toxic than oxides. Soil toxicity due to Ag, Bi, Tl, and Te contamination was dependent on soil particle size distribution, organic matter content, and soil structure. A series of soil sensitivity to changes in microbial biomass and basal soil respiration when contaminated with the studied pollutants: Haplic Arenosols > Haplic Chernozems > Haplic Cambisols. When diagnosing and assessing the health of soils contaminated with Ag, Bi, Tl, and Te, it is advisable to use indicators of soil microbiological activity.
Lipid Nanoparticles as a Shuttle for Anti-Adipogenic miRNAs to Human Adipocytes

Obesity and type 2 diabetes are major health burdens for which no effective therapy is available today. One treatment strategy could be to balance the metabolic functions of adipose tissue by regulating gene expressions using miRNAs. Here, we have loaded two anti-adipogenic miRNAs (miR26a and miR27a) into a pegylated lipid nanoparticle (PEG-LNP) formulation by a single-step microfluidic-assisted synthesis step. For the miRNA-loaded LNPs, the following system properties were determined: particle size, zeta potential, miRNA complexation efficiency, and cytotoxicity. We have used a human preadipocyte cell line to address the transfection efficiency and biological effects of the miRNA candidates at the gene and protein level. Our findings revealed that the upregulation of miR27a in preadipocytes inhibits adipogenesis by the downregulation of PPARγ and the reduction of lipid droplet formation. In contrast, miR26a transfection in adipocytes induced white adipocyte browning detected as the upregulation of uncoupling protein 1 (UCP1) as a marker of non-shivering thermogenesis. We conclude that the selective delivery of miRNAs by PEG-LNPs to adipocytes could offer new perspectives for the treatment of obesity and related metabolic diseases.
Cross-Cultural Learning Strategies for Entrepreneurship Education: Implications for Lifetime Education Towards Civil Society

Islamic universities have the belief and view that start-up activities create demand that will boost the economy. However, entrepreneurial activities have not developed in universities. This paper attempts to analyze the findings of a survey-based study of students receiving entrepreneurship education at IAIN Sjech M. Djamil Djambek Bukittinggi in West Sumatra. The main objective of this research is to compare management attitudes and students' attitudes towards entrepreneurship within the framework of cultural studies. Methodology/approach: using ratio measurement in quantitative research. For example, the sample will be asked to decide whether- those who are self-employed are seen as 1=failures, 2=not failures but also failures, 3=very successful. To ensure maximum reliability and validity, the questionnaire was administered in person. The Thurstone scale method with intervals used to evaluate quantitative research is the same. The results of the study show that the main difficulties in setting up and starting a business at UIN Sjech M. Djamil Djambek Bukittinggi are cultural and activity perceptions. Prospective Entrepreneurs/entrepreneurs who graduate from UIN Sjech M. Djamil Djambek Bukittinggi must build sustainable networks and relationships during and after creating a new business. Entrepreneurship education will be an important subject for Islamic tertiary institutions, so it is important to establish culturally adapted programs.
Treat to Target ASCVD Risk with Oral Non-statins and Bempedoic Acid: DELPHI Statement

Background: In Asian countries, the high endemicity of Coronary Artery Disease (CAD) has been associated with an increase in premature deaths requiring a multi-interventional or multidisciplinary approach to control the cardiovascular risk traits associated with most of these cases. Objective: ESC recommendations on lipid goals of ≤55 mg/dl in Atherosclerotic cardiovascular disease (ASCVD)
Summary of methodology used in enterotoxigenic Escherichia coli (ETEC) challenge experiments in weanling pigs and quantitative assessment of observed variability

Abstract Postweaning diarrhea in pigs is often caused by the F4 or F18 strains of enterotoxigenic Escherichia coli (ETEC). To evaluate interventions for ETEC, experimental infection via a challenge model is critical. Others have reviewed ETEC challenge studies, but there is a lack of explanation for the variability in responses observed. Our objective was to quantitatively summarize the responses and variability among ETEC challenge studies and develop a tool for sample size calculation. The most widely evaluated response criteria across ETEC challenge studies consist of growth performance, fecal consistency, immunoglobulins, pro-inflammatory cytokines, and small intestinal morphology. However, there is variation in the responses seen following ETEC infection as well as the variability within each response criteria. Contributing factors include the type of ETEC studied, dose and timing of inoculation, and the number of replications. Generally, a reduction in average daily gain and average daily feed intake are seen following ETEC challenge as well as a rapid increase in diarrhea. The magnitude of response in growth performance varies, and methodologies used to characterize fecal consistency are not standardized. Likewise, fecal bacterial shedding is a common indicator of ETEC infection, but the responses seen across the literature are not consistent due to differences in bacterial enumeration procedures. Emphasis should also be placed on the piglet’s immune response to ETEC, which is commonly assessed by quantifying levels of immunoglobulins and pro-inflammatory cytokines. Again, there is variability in these responses across published work due to differences in the timing of sample collection, dose of ETEC pigs are challenged with, and laboratory practices. Small intestinal morphology is drastically altered following infection with ETEC and appears to be a less variable response criterion to evaluate. For each of these outcome variables, we have provided quantitative estimates of the responses seen across the literature as well as the variability within them. While there is a large degree of variability across ETEC challenge experiments, we have provided a quantitative summary of these studies and a Microsoft Excel-based tool was created to calculate sample sizes for future studies that can aid researchers in designing future work.
Self-control and Self-consciousness: Regulation or Acceleration of Self-discrepancy Distress?

: The present study explores the connection between the actual/ideal (A/I) and actual/ought (A/O) self--discrepancies and negative emotional states such as stress, anxiety and depression. Moreover, it seeks to understand the effects of potentially intervening variables, self-control //and self-consciousness, on the affect-discrepancy relationship. 638 participants (60% female, aged 18-55) participated in the study. They filled out questionnaires measuring actual/ ideal self-discrepancy, actual/ought self-discrepancy, self-control, private/public self-consciousness and psychological distress (depression, anxiety and stress; DAS). The results revealed that both, A/O and A/I self-discrepancies, are positively associated with DAS but do not have a predictive value for them. However, depression, anxiety and stress are significantly predicted by low self-control and high personal self-consciousness. Also, the study confirms that selfcontrol and self-consciousness moderate affect-discrepancy relationship: self-control is a significant moderator of the relationships between (1) A/I and A/O self-discrepancy and depression and (2) A/I and A/O self-discrepancy and stress. Also, public self-consciousness moderates the relationship between A/O self-discrepancy and stress. In this respect those who have high self-control and high self-consciousness are less likely to experience negative emotional reactions related to the discrepant self-constructs.