Miracle-dz/UniFAR-FTUs huggingface dataset:
A survey of speech-language pathology treatment for non-progressive dysarthria in Australia

Abstract Aim: To identify management practices of Australian speech-language pathologists (SLPs) in the treatment of non-progressive dysarthria using a subsystem approach, and to explore SLPs’ consideration and implementation of the theoretical underpinnings of non-progressive dysarthria management. Method: A 39-item online survey was distributed to Australian SLPs, with 80 responses suitable for data analysis. Results: Practices of SLPs were variable for the management of the speech subsystems. The Lee Silverman Voice Treatment (LSVT®) was the most commonly used manualised treatment program, and was employed by 63.77% of respondents. Almost all SLPs (>88%) provided strategies to improve functional communication. There was no clear preference for low tech alternative and augmentative communication (AAC) devices. Speech generating devices were the most commonly employed high tech device. Almost two-thirds of respondents used non-speech oral motor exercises (NSOMEs) in treatment. SLPs had varied frequencies and models of service delivery for intervention. SLPs valued interventions targeting the activity and participation domains of the ICF, however this was restricted by the treatment context and resources available. The majority of SLPs (92.06%) were aware of the principles of motor learning, however many were unsure regarding the specifics of implementation. Conclusion: There is a clear need for further research into the efficacy of treatment techniques to guide decision-making.
Real-world impact of postmastectomy radiotherapy in T1–2 breast cancer with one to three positive lymph nodes

Background The utility of postmastectomy radiotherapy (PMRT) in breast cancer patients with T1–2 (tumor size ≤5 cm) and N1 (one to three lymph nodes involved) disease remains controversial. The aim of this population-based study was to investigate the effectiveness of PMRT in this patient subset in the current clinical practice. Methods We included T1–2N1 breast cancer patients treated with mastectomy from 2004 to 2012 using the data form the Surveillance, Epidemiology, and End Results program. The association of PMRT administration with breast cancer-specific survival was determined using multivariable Cox analysis. Results We identified 10,248 patients of this study, including 3,725 (36.3%) received PMRT and 6,523 (63.7%) patients did not receive PMRT. Use of PMRT showed increase from 2008 onward; the percentage of patients receiving PMRT was 30.6% in 2004 and was 47.1% in 2012 (P<0.001). Patients diagnosis after 2008, aged <50 years, high tumor grade, T2 stage, and ≥2 positive lymph nodes were independently related to PMRT receipt. Multivariate analysis indicated that PMRT was not related to better breast cancer–specific survival compared to those without PMRT both before (P=0.186) and after propensity score matching (P=0.137). Conclusions In breast cancer with T1–2N1 disease, PMRT does not appear to improve survival in the era of modern systemic therapy.
INHIBITION OF OLIVE KNOT DISEASE BY POLYPHENOLS EXTRACTED FROM OLIVE MILL WASTE WATER

Olive mill waste water (OMW) and phenolic extracts, used at different concentrations in vitro displayed a high level of antibacterial activity against Pseudomonas savastanoi pv. savastanoi, the causal agent of olive knot disease. In in planta experiments, phenolic compounds used at three concentrations (1000, 500 and 100 mg l-1) completely inhibited the formation of knots on twigs inoculated with pathogenic strains IVIA 1628 and Aw9. GC/MS analysis revealed the presence of hydroxytyrosol in high concentration, in addition to tyrosol, catechol, caffeic acid and p-coumaric acid, suggesting their antibacterial effect. Copper treatment was less effective than phenolic compounds since the inhibition percentages of knot formation were 6% and 12% for IVIA1628 and Aw9, respectively. These results show that phenolic compounds extracted from OMW and rich in hydroxytyrosol can be excellent substitutes of copper compounds for controlling olive knot disease.
Caracterización clínica y severidad de los trastornos temporomandibulares en pacientes adultos

Background: temporomandibular disorders are conditions in the Temporomandibular Joint, masticatory muscles, associated structures and disorders related to the function of the stomatognatic system. Objective: to determine the clinical characterization and severity of temporomandibular disorders in adult patients. Methods: a cross-sectional descriptive study was carried out in the Dentistry Prosthesis consultation of the municipality of Nuevitas, Camaguey province, in the period from January to July 2018, from a universe of 133 patients diagnosed with temporomandibular disorders, a non-probabilistic sample was selected constituted by 77 patients, previous sample calculation. Results: the female sex predominated and the age group between 40-49 years. It was highlighted as the main degree of dysfunction according to the moderate. Observed emotional stress, occlusal interferences, and bruxism as risk factors was observed. The main clinical manifestations in the patients examined were joint noises in 71.4 %. Conclusions: the clinical characterization and severity of the temporomandibular disorders allowed to know a predominance in the female sex, during the fourth decade of life, with a moderate degree of dysfunction, where the main risk factors were emotional stress, occlusal interferences and bruxism. The majority of patients presented main clinical manifestation. DeCS: TEMPOROMANDIBULAR JOINT DISORDERS/diagnosis; STRESS, PSYCHOLOGICAL; BRUXISM; ADULT; CROSS-SECTIONAL STUDIES.
Does Student Loan Forgiveness Drive Disability Application?

Student loan debt in the US exceeds $1.3 trillion, and unlike credit card and medical debt, typically cannot be discharged through bankruptcy. Moreover, this debt has been increasing: the share of borrowers leaving school with more than $50,000 of federal student debt increased from 2 percent in 1992 to 17 percent in 2014. However, federal student loan debt discharge is available for disabled individuals through the Department of Education's Total and Permanent Disability Discharge (TPDD) mechanism through certification of a total and permanent disability. In July 2013, the TPDD expanded to include receipt of Social Security Disability Insurance (SSDI) or Supplemental Security Income (SSI) as an eligible category for discharge, provided medical improvement was not expected. Using data from the Survey of Income and Program Participation (SIPP) matched to SSI and SSDI applications, we find that SSDI and SSI application rates increased among respondents with student loans relative to rates among those without student loans. Our estimates suggest the policy change raised the probability of applying for SSDI or SSI in a given quarter among student loan-holders by 50% (baseline rate per quarter is approximately 0.3%), generally increasing SSI and SSDI awards. However, these induced award recipients were unlikely to receive the disability designation necessary to obtain student loan discharge. Given that the geographic distributions of student loan indebtedness and historical SSDI/SSI program participation differ, there are strong implications for both the size and location of SSDI and SSI beneficiaries. Furthermore, these findings highlight the importance of learning from policy changes in programs that interact with SSDI and SSI to better understand the drivers of disability program participation.
Understanding the physics concept between guided inquiry or open inquiry

The ability to solve problems is one of the skills required by learners in facing the challenges of the 21st century. Conceptual understanding is an integral part of problem-solving skills. Inquiry is a recommended learning strategy to gain an understanding of concepts in science learning. This research is an experiment, which compares learning strategy of guided inquiry or open inquiry to understanding the concept of physics. As a modular variable, self-regulated learning (SRL) is used. The research design uses factorial 3 × 2, and involving 298 students in Senior School of Malang City. Hypothesis uses 2-way ANOVA. The results showed: 1) there is a difference concept understanding between the use of guided inquiry learning strategy, free and conventional inquiry; 2) there is a difference of concept understanding between students having high SRL with low SRL; 3) there is influence between interaction of inquiry learning strategy with SRL to understanding concept.
Role of the forkhead transcription factor Foxa2 in the development of the ventral mesencephalon: a study using conditional mouse mutants.

The developing mesencephalon consists of two distinct domains. The dorsal domain, the tectum, gives rise to the superior and inferior colliculi, which in the adult receives information from the optic and auditory systems respectively. The ventral domain gives rise primarily to 3 distinct nuclei which are involved in the control of motor movement, such as the mesencephalic dopaminergic neurons, which are the neurons affected in Parkinson's disease, the oculomotor complex and the red nucleus. Forkhead transcription factors of the A subgroup, Foxa1 and Foxa2, are expressed in the ventral midbrain, in addition to being expressed in the notochord, floorplate and gut during embryonic development. In this study, I focused on the role of Foxal, a member of the forkheadVwinghelix family of transcription factors in the specification of the ventral mesencephalic neurons. To address the role of Foxa1 specifically in the mesencephalon, we have generated a conditional allele of Foxa2, referred to as Foxa2ox and crossed this mouse line with Wntl-Cre transgenic animals. Inactivation of Foxa2 protein in mesencephalic progenitors of Wntl-Cre Foxa'f0 embryos occurred by E8.5. Severe reduction in the numbers of Islet 1* oculomotor, Brn3a+ red nucleus and tyrosine hydroxylase* dopaminergic neurons were observed in Foxa2 conditional mutant embryos at El2.5, which were preceded by changes in the expression of the morphogen Shh as well as Foxal and Nkx transcription factors. Detailed phenotypic characterization by histology, RNA in-situ hybridization and immunohistochemistry has revealed novel roles for Foxa2 in regulating the patterning of mesencephalic progenitors as well as their differentiation. In collaboration with another postdoctoral fellow in the laboratory, we have also shown that Foxal plays a very similar role and can compensate for the function of Foxa2 in the ventral mesencephalon.
Seascape genomics as a new tool to empower coral reef conservation strategies: An example on north‐western Pacific Acropora digitifera

Coral reefs are suffering a major decline due to the environmental constraints imposed by climate change. Over the last 20 years, three major coral bleaching events occurred in concomitance with anomalous heatwaves, provoking a severe loss of coral cover worldwide. The conservation strategies for preserving reefs, as they are implemented now, cannot cope with global climatic shifts. Consequently, researchers are advocating for preservation networks to be set‐up to reinforce coral adaptive potential. However, the main obstacle to this implementation is that studies on coral adaption are usually hard to generalize at the scale of a reef system. Here, we study the relationships between genotype frequencies and environmental characteristics of the sea (seascape genomics), in combination with connectivity analysis, to investigate the adaptive potential of a flagship coral species of the Ryukyu Archipelago (Japan). By associating genotype frequencies with descriptors of historical environmental conditions, we discovered six genomic regions hosting polymorphisms that might promote resistance against heat stress. Remarkably, annotations of genes in these regions were consistent with molecular roles associated with heat responses. Furthermore, we combined information on genetic and spatial distances between reefs to predict connectivity at a regional scale. The combination of these results portrayed the adaptive potential of this population: we were able to identify reefs carrying potential heat stress adapted genotypes and to understand how they disperse to neighbouring reefs. This information was summarized by objective, quantifiable and mappable indices covering the whole region, which can be extremely useful for future prioritization of reefs in conservation planning. This framework is transferable to any coral species on any reef system and therefore represents a valuable tool for empowering preservation efforts dedicated to the protection of coral reefs in warming oceans.
What do women know about breast density? A public screening program perspective

Background: This study assesses knowledge of breast density, one of breast cancer′s strongest risk factors, in women attending a public mammographic screening program in Western Australia that routinely notifies women if they have dense breasts. Methods: Survey data was collected from women who were notified they have dense breasts and women who had not (controls). Descriptive data analysis was used to summarize responses. Results: Of the 6183 women surveyed, over 85% of notified women knew that breast density makes it difficult to see cancer on a mammogram (53.9% in controls). A quarter of notified women knew that having dense breasts puts women at increased risk for breast cancer (13.2% in controls). Overall, 50.1% of notified women indicated that they thought the amount of information provided was “just right” and 24.9% thought it was “too little”, particularly women notified for the first time (32.1%). Conclusion: The main message of reduced sensitivity of mammography in women with dense breasts provided by the screening program appears to be getting though. However, women are largely unaware that increased breast density is associated with increased risk. Women notified of having dense breasts for the first time could potentially benefit from additional information.
Coverage Error in Data Collection Combining Mobile Surveys With Passive Measurement Using Apps: Data From a German National Survey

Researchers are combining self-reports from mobile surveys with passive data collection using sensors and apps on smartphones increasingly more often. While smartphones are commonly used in some groups of individuals, smartphone penetration is significantly lower in other groups. In addition, different operating systems (OSs) limit how mobile data can be collected passively. These limitations cause concern about coverage error in studies targeting the general population. Based on data from the Panel Study Labour Market and Social Security (PASS), an annual probability-based mixed-mode survey on the labor market and poverty in Germany, we find that smartphone ownership and ownership of smartphones with specific OSs are correlated with a number of sociodemographic and substantive variables. The use of weighting techniques based on sociodemographic information available for both owners and nonowners reduces these differences but does not eliminate them.
Remembering Colonialism and Encountering Refugees: Decolonization in Jenny Erpenbeck’s Go, Went, Gone

This article reads the German writer Jenny Erpenbeckʼs influential novel Go, Went, Gone (2015) as a significant contribution to connecting the current refugee problematic to the decolonization discourse in the German and European public sphere. Along with the public discussions about looted art objects during German colonialism in existing German museums and the emerging Humboldt Forum, the novel registers a shift in the culture of collective memory from a singular focus on the holocaust toward a more inclusive and more connected memory of multiple pasts of violence and atrocity, including German colonialism. This multilayered memory reveals the refugee problem not as something external and unexpected but as something that is deeply connected to German and European history. The novelʼs protagonist Richard, an educated former East German, is the novelistʼs experiment to articulate the urgent need for decolonization as a possible solution toward the refugee problematic. The novel depicts the reality and imagines a decolonized world in which less discrimination, less exclusion, more hospitality, and more acceptance might be possible.
Impact of CSO Manage Training Programs on Individual and Organizational Performance

Human resource problems faced by CSOs are the limited number of employees compared to organizational activities, low employee skills, and lack of employee experience in managing the activities of the organization. Based on these problems, NICE Indonesia conducted a CSO Manage training program which was participated by 10 CSOs. This research was conducted with the aim of evaluating the CSO Manage training program. 10 CSO participants in the CSO Manage training program were taken entirely as research samples. Evaluation of the CSO Manage training program is carried out using the Kirkpatrick four-level evaluation model. The results showed that the objectives of the CSO Manage training program could be achieved as indicated by an increase in knowledge and changes in participant behavior, as well as an increase in individual and organizational performance. Keywords: Training, CSO Manage, NICE Indonesia, Kirkpatrick Four-Level Evaluation Model DOI : 10.7176/EJBM/12-2-05 Publication date: January 31 st 2020
Response of lactating dairy ruminant to different profiles of dietary calcium soaps of fatty acids

Nutrition has a significant effect on reproduction and lactation in Ruminant. Supply of require nutrient of dairy cows and ewes in early lactation is the main challenges that will be considered, since in most cases the animals facing negative energy balance after calving and the beginning of the period of lactation. Negative energy balance may sometimes result in reduced livestock production and metabolic diseases and thus negatively affected the growth of lambs and calves. The use of energy-rich diets, especially during the rearing period lactation can help to solve this problem. Studies showed that fat supplementation has positive effects on dairy cattle during a 120-day lactation period. Milk fat yield increased linearly during the nursing period, but not in the rest of lactation, with increased CSFA feeding. The absence of a positive response in milk fat yield during the milking period, even with high levels of CSFA in the diet, indicates a decrease in transfer of fat from CSFA to milk as lactation advanced, which is quantified by the lower relative milk fat yield response with high CSFA levels at the end of lactation
ADN ribosomique 5S chez Arabidopsis thaliana : dynamique chromatinienne et ARN polymérase IV

Chez Arabidopsis thaliana, Les genes d'ARN 5S sont regroupes en blocs situes dans l'heterochromatine pericentromerique des chromosomes 3,4 et 5. La transcription des genes d'ARN 5S est regulee par des facteurs epigenetiques alterant notamment leur structure chromatinienne. Une etude a ete menee durant les premieres etapes du developpement post-germinatif pour identifier les evenements et des facteurs conduisant a l'elaboration de telles structures. Nous avons pu observer une decompaction de l'ADNr 5S immediatement suivie d'une recondensation. Ces phenomenes impliquent respectivement ROS 1 et l'ARN polymerase IV. L'etude des formes Pol IVa et Pol IVb nous indique que Pol IVb, en plus de son activite partenaire de Pol IVa, possede une action specifique dediee au locus d'ADNr 5S du chromosome 4. Cette nouvelle activite de Pol IVb, qui est indispensable au silencing et a la compaction de ce locus, semble independante de la voie classique de methylation de l'ADN dependante des ARN.
‘Flexible ongoing’: the young university student as homo promptus

ABSTRACT Drawing from a study of young university students in Australia, France and the U.K., homo promptus represents the authors’ effort to trace how young people are positioned within discourses of higher education and employment to provide a conceptual shape to emergent characteristics of their otherwise diverse lives. We suggest that homo promptus is: entrepreneurial and strategic; plans adaptively for the future while living life in the short-term; not tethered to a single place; permanently in ‘situational’ mode and lives in waithood. We also argue that overlaying the figure of homo promptus is a complex affective combination of optimism, pessimism and anxiety evident in our interviewees’ narratives. We then briefly attempt to reflexively locate ourselves as youth researchers in relation to the study from which this paper is drawn, outlining certain caveats and limitations of presenting another limited figure of youth, as discussed previously by Threadgold (2019) in this journal, but one which seeks to bring some clarity to the sometimes messy work of youth research.
OH reactivity from different tree species: Investigating the missing reactivity in a boreal forest

Abstract. In forested area, a large fraction of total hydroxyl radical (OH) reactivity remain unaccounted for. Very few studies have been looking at total OH reactivity from biogenic emissions and its variations. In the present study, we investigate the total OH reactivity from three common boreal tree species (Scots pine, Norway spruce, and Downy birch), by comparing it with the calculated reactivity from the chemically identified emissions. Total OH reactivity was measured using the Comparative Reactivity Method (CRM), and the chemical composition of the emissions was quantified with two gas chromatographs coupled to mass spectrometers (GC-MSs). Dynamic branch enclosures were used and emissions from one branch of a tree at the time were measured by rotating between them periodically. Results show that birch had the highest values of total OH reactivity of the emissions (TOHRE), while pine had the lowest. The main drivers for the known reactivity of pine and spruce were monoterpenes and sesquiterpenes. For birch, emissions were dominated by sesquiterpenes, even though monoterpenes and GLVs could be found too. However, calculated reactivity values remained low leading to the highest missing fraction of reactivity (>96 %), while pine and spruce had similar missing reactivity fractions between 56 % and 82 % (higher in the spring and decreasing as the summer proceeded). The high average values were driven by low reactivity periods and the fraction of missing reactivity got smaller for pine and spruce when the TOHRE values increased. Important exceptions were identified for periods when the emission profiles changed from terpenes to Green Leaf Volatiles (GLVs), a family of compounds containing a 6 carbon atoms backbone with various functionalities (e.g. alcohols, aldehydes, esters) that indicate that the plant is suffering from stress. Then, very high TOHRE values were measured and the missing fraction remained high. This study found a different trend in the missing OHRE fraction of Norway spruce from spring to autumn compared to one previous study (Nolscher et al., 2013), which indicates that additional studies are required to fully understand the complexity of biogenic reactive emissions. Future studies of boreal trees in situ should be conducted to confirm the findings presented.
The Effect of Price, Ease of Transaction, Information Quality, Safety, and Trust on Online Purchase Decision

This research aims to analyze the effect of price, ease of transaction, information quality, safety, and trust on online purchase decision. Applying purposive sampling technique, the sample was students of the Department of Management, Faculty of Economics and Business, University of Jember that consisted of 100 respondents. This study used quantitative data sourced from primary data. Data were analyzed using multiple linear regression. Results showed that, both partially and simultaneously, the variables of price, ease, information quality, safety, and trust had a significant positive effect on online purchase decision.