Miracle-dz/UniFAR-FTUs huggingface dataset:
Clinical and bacteriological profiles of neonatal sepsis in a tertiary hospital, south-western Nigeria.

Introduction Antibiotic-resistant bacteria complicate treatment options in neonatal sepsis, especially in developing countries. This study determined the epidemiology and bacteriological characteristics of neonatal sepsis at a tertiary hospital, in southwest Nigeria. Methods This was a cross-sectional study from December 2017 to April 2019 among admitted babies with clinical neonatal sepsis. Blood culture was performed by semi-automated system, sepsis biomarker assay (serum procalcitonin) by a semi-quantitative kit while proforma was used to capture clinico-demographic data. Bacterial identification, antibiotic susceptibility patterns, determination of genetic elements mediating resistance, were performed by standard methods and polymerase chain reaction protocols, respectively. Quantitative data were expressed as frequencies, mean; bivariate and multivariate analyses were performed by Chi-square or Fishers' exact test and logistic regression. Results Of the 192 cases of neonatal sepsis enrolled, 42.7% (82/192) were blood culture positive. Factors associated with blood culture positivity included respiratory rate ≥60 bpm (60/82; p<0.03), lethargy/unconsciousness (59/82; FE=7.76; p<0.001), grunting respiration (54/82; p=0.04), meconium passage before birth (17/82; p=0.03) and prolonged rupture of membranes ≥24 hours (50/82; FE=6.90; p=0.01). On the other hand, mortality in the neonates was associated with elevated serum procalcitonin assay (>0.5 ng/mL) χ2=13.58; p=0.03] and Gram-negative bacteremia (χ2=24.64; p<0.001). The most common bacterial isolates were Staphylococcus aureus (42/82), coagulase-negative Staphylococcus spp. (17/82), Enterobacter spp. (8/82), and Acinetobacter spp. (6/82). Methicillin resistance was present in 85.7% (36/42) of Staphylococcus aureus and 52.9% (9/17) of coagulase-negative Staphylococcus, while extended-spectrum beta-lactamase (ESBL) and AmpC enzymes were present in (21.1%; 4/19) of the Gram-negative bacilli. Conclusions Almost half of the cases of clinically diagnosed neonatal sepsis have bacterial etiologic confirmation of sepsis. Gram-negative bacteremia and high serum procalcitonin predict mortality in neonatal sepsis. There was high resistance to common antibiotics for the treatment of neonatal sepsis in our settings.
Trinity College Digital Repository Trinity College Digital Repository

Featured Application: Teleoperated control of legged locomotion for robotic proxies. Abstract: Teleoperated systems enable human control of robotic proxies and are particularly amenable to inaccessible environments unsuitable for autonomy. Examples include emergency response, underwater manipulation, and robot assisted minimally invasive surgery. However, teleoperation architectures have been predominantly employed in manipulation tasks, and are thus only useful when the robot is within reach of the task. This work introduces the idea of extending teleoperation to enable online human remote control of legged robots, or telelocomotion, to traverse challenging terrain. Traversing unpredictable terrain remains a challenge for autonomous legged locomotion, as demonstrated by robots commonly falling in high-proﬁle robotics contests. Telelocomotion can reduce the risk of mission failure by leveraging the high-level understanding of human operators to command in real-time the gaits of legged robots. In this work, a haptic telelocomotion interface was developed. Two within-user studies validate the proof-of-concept interface: (i) The ﬁrst compared basic interfaces with the haptic interface for control of a simulated hexapedal robot in various levels of traversal complexity; (ii) the second presents a physical implementation and investigated the efﬁcacy of the proposed haptic virtual ﬁxtures. Results are promising to the use of haptic feedback for telelocomotion for complex traversal tasks.
Use of splinting in traumatized primary teeth: A systematic review of case reports

The aim of this study was to explore the use of splinting in the management of traumatized primary dentition in case reports published in the literature. Systematic searches were performed in the main health databases to identify case reports (a) with children presenting trauma in primary teeth, and (b) those that described any outcomes related to the use of splints in the management of traumatized primary teeth. The stages of study selection, data extraction and risk of bias analysis were performed. Descriptive data analysis was described. The reporting of information from this review was based on the PRISMA 2020 guidelines. Of the total number of studies initially found (n=246), eight were case reports. Outcomes of splint immobilization in primary teeth with luxation (intrusion, extrusion, and lateral displacement), intra-alveolar root fracture and/or alveolar fracture were reported. All case reports described splinting as a viable technique for immobilizing traumatized primary teeth, regardless of the type of traumatic dental injury (TDIs) and splinting technique used. Only case report verified the effectiveness of the splinting in the management of dentoalveolar trauma and demonstrated the clinical effectiveness of the contentive approach. Based on low evidence studies with a moderate risk of bias, it was observed that the use of splints for the management of alveolar bone fractures and intrusive root fractures, and in specific cases of teeth with lateral luxation, can bring additional benefits to the dento-alveolar health of traumatized primary teeth.
Motivation of teachers based on the school's culture and leadership of the principal

This study aimed to determine and analyze the influence of the principal's leadership variables and school culture on the teacher’s work motivation. This used a cross-sectional survey design to determine and measure the level of influence between variables, such as principals' leadership, school culture, and teacher work motivation. Research questionnaires were distributed to 220 teachers to find out their perceptions of the principal's leadership, school culture, and teacher’s work motivation, then analyzed using the SEM-PLS. The results of the analysis revealed that the principal's leadership has a positive and significant direct effect on school culture. The principal's leadership does not have a direct significant effect on the teacher’s work motivation, school culture has a direct positive and significant effect on the teacher’s work motivation, and there is a positive indirect effect and significant to the teacher’s work motivation through school culture. Keywords: Leadership; motivation; principal; school culture.
Assessment of Parents' Knowledge Regarding Pediatric Glucose-6-Phosphate Dehydrogenase Deficiency in Saudi Arabia

Introduction Glucose-6-phosphate dehydrogenase deficiency (G6PD) is recognized as the most common enzyme disorder globally, impacting over 400 million individuals. The disease is highly prevalent in Saudi Arabia. This study aimed to assess parents' awareness of G6PD in Saudi Arabia and identify misconceptions for targeted educational interventions, aiming to enhance awareness and condition management. Methods A structured online questionnaire was used to gather information from July 18th, 2023, to August 1st, 2023. The survey targeted parents of Saudi children who resided in various regions across Saudi Arabia and collected a total of 531 responses. Data analysis involved descriptive statistics, chi-square tests, and probit regression. A significance level of p<0.05 was employed to interpret the results. Results A statistically significant associations were found among parents with Glucose-6-phosphate dehydrogenase deficiency-deficient children, including gender-related (odd ratio = 2.91, 99% CI: 1.986-4.301), awareness of the genetic link (odd ratio = 2.49, 99% CI: 1.701-3.639), specific medications (odd ratio =1.890, 99% CI: 1.262-2.853), loss of appetite (odd ratio= 0.629, 95% CI: 0.398-0.990), jaundice (odd ratio = 3.01, 99% CI: 1.877-4.983), increased fluid intake (odd ratio= 1.53, 95% CI: 1.091-2.139), receiving blood transfusions (odd ratio = 1.54, 95% CI: 1.101-2.157), seeking online information (odd ratio = 1.92, 99% CI: 1.250-2.940), and consulting healthcare professionals (odd ratio = 3.24, 99% CI: 2.065-5.107). Conclusion Regional disparities in glucose-6-phosphate dehydrogenase deficiency awareness among parents in Saudi Arabia are evident, with the central region demonstrating the highest level of awareness. Understanding glucose-6-phosphate dehydrogenase deficiency risk factors, medication triggers, and clinical symptoms plays a significant role in parental knowledge, emphasizing the need for region-specific education and awareness programs.
Examining the Accommodation Experience in Historical Buildings with Content Analysis: Amasya Mansions Example

In this study, which aims to examine online tourist comments about historical mansion hotels in Amasya, which has shown rapid development in recent years in terms of tourism activity, tourist comments on the TripAdvisor platform were used. In the research, comments on TripAdvisor regarding Amasya's mansion hotels were examined using the "word cloud technique" in two different categories: positive and negative. According to the findings obtained from the collected data, the general scores of the 10 mansion hotels operating in Amasya examined within the scope of the research are well above the average level on the TripAdvisor platform. In other words, tourists who experience mansion hotels in Amasya tend to give high scores on TripAdvisor. The most striking words that emerged in the word cloud where positive comments about Amasya mansion hotels were examined were words such as "hotel, mansion, Amasya, breakfast, room, Yeşilırmak, staff. ” According to the data provided with the help of the "word cloud" obtained from the negative comments about Amasya mansion hotels on TripAdvisor, the words that attract the most attention are expressions such as "noise, music, car park, and sleep. ”
BIODIVERSITY AND CONSERVATION OF BUTTERFLIES IN THE EASTERN GHATS

Butterflies (Lepidoptera:Rhopalocera) the lovely and graceful insects provide economic and ecological benefits to the human society. Having multihued colors on their wings, they enhance the earth’s beauty incontestably, and add immense aesthetic value to the ambient environment. They accomplish pollination, a key stone ecological process in natural sustainability throughout the world. Being development on vegetation on both as adults and larvae, they involve themselves in complex feeding relationships with green plants. As adults they require a succession of adequate nectar resources. Nectar provides energy for flight, which is vital to find makes and to disperse the species. As larvae, butterflies are typically host specific and often show a “Botanical instinct” in that closely related butterfly species choose closely related plants. As such butterflies provide the best rapid indicators of habit quality and also they are the sensitive indicators of climatic change (Goodden, 1974).
The Effects of Stimulus and Consumer Characteristics on the Utilization of Nutrition Information and Purchase Intention

This research study investigates the effect of stimulus and consumer characteristics on the utilization of nutrition information. Details of stimulus in this research study are negative arousal consequence information (paired 3 levels: high, low, control) and reference information (with and without information on Recommended Dietary Allowance or RDA). Meanwhile, details for consumer characteristics are nutrient familiarity (familiar, unfamiliar), and preventive orientation (high, low). The measurements of utilization of nutrition information are through the motivation to process, ability to process, and purchasing intention. This quantitative research employs 3x2x2 experimental design. Based on the data of 353 respondents, the findings showed that the variables affecting motivation to process are consequence information, nutrient familiarity, and preventive orientation. In contrast, preventive did not affect the purchasing intention. This study can predict the best strategy of nutrition information that makes people utilize the knowledge and attract them regarding their purchasing intention. This will not only help policy makers design legal polices that promote health but will also help corporations develop products that better match consumers’ desire for healthy food.
Qualitative Research Design: An Interactive Approach

Preface Preface to the First Edition 1. A Model for Qualitative Research Design 2. Goals: Why Are You Doing This Study? 3. Conceptual Framework: What Do You Think Is Going On? 4. Research Questions: What Do You Want to Understand? 5. Methods: What Will You Actually Do? 6. Validity: How Might You Be Wrong? 7. Research Proposals: Presenting and Justifying a Qualitative Study Appendix: An Example of a Qualitative Proposal References Index About the Author
A lexical bundle analysis of art-related crowdfunding projects

In the context of Open Science, crowdfunding projects are gaining increasing attention. They are becoming an alternative way of funding research and an opportunity for researchers across the disciplines to share and disseminate their work widely while engaging their potential backers. The aim of this paper is to analyze crowdfunding projects online by examining language-in-use at the level of phraseology, understanding the latter from a lexical bundle approach. Using corpus analytical approaches, the study findings show that there is a recurrence of lexical bundles conveying deontic meanings used to persuade the potential backers that the project and the research methods proposed for carrying it out are reliable and therefore trustable. Lexical bundles expressing gratitude and politeness are also recurrent, not unexpected considering that crowdfunding proposals aim to prompt the audience’s participation through donation. The findings further reveal how distinct discourse style and language features especially frequent in the conversational register realise the main communicative purpose of the genre, namely, to build credibility and trust in research with a view to persuasively enticing the backers’ audiences to donate money.
Adiponectin exhibits proliferative and anti-apoptotic effects on ovarian cancer cells via PI3K/Akt and Raf/MEK/ERK pathways

Purpose: To elucidate the effects and the underlying mechanism of adiponectin on human ovarian cancer cells. Methods: The level of adiponectin, adiponectin receptor-1, caspase-3 and bcl-2 in the serum and ascites of the patients were measured with enzyme-linked immunosorbent assay (ELISA), qPCR and Western blotting. The human ovarian cancer cell lines (Caov3 and SKOV3) were enumerated using 3-(4,5-dimethylthiazol-2-yl)-2,5-tetrazolium bromide (MTT) assay. Western blotting was also used to determine the levels of p-Akt, p-ERK and cyclin B. Results: Serum and ascite levels of adiponectin were significantly higher in ovarian cancer patients than in healthy patients (p < 0.05). Expression of adiponectin in the serum and ascites of patients in FIGO stage IV was remarkably higher than in earlier stages (p < 0.05). The proliferative effect of adiponectin on ovarian cells was dose-dependent. Adiponectin treatment significantly increased the expression of cyclin B in Caov3 and SKOV3, and reduced the levels of caspase-3 and bcl-2. Inhibitors of PI3K and MEK pathways significantly reduced the proliferation of attenuated Caov3 and SKOV3 by up-regulating cyclin B upon adiponectin treatment (p < 0.05), and thus alleviated the inhibitory effect of adiponectin on the expressions of caspase-3 and bcl-2. Conclusion: The findings demonstrate that adiponectin promotes proliferation of the cells via the PI3K/Akt and Raf/MEK/ERK pathways, and also provide new insights into ovarian cancer treatmment. Keywords: Adiponectin, Ovarian cancer, Proliferation, Apoptosis, PI3K/Akt pathway
Linker, relativizer, nominalizer, tense-particle

The Ezafe particle is well known from recent work on Persian syntax, but its historical origins and developmental pathways have received less attention. This chapter redresses the balance by considering the Ezafe in a related West Iranian language, Northern Kurdish. In Northern Kurdish, the Ezafe has largely retained its demonstrative/relativizer origins, and also occurs as a nominalizer in the sense employed in this volume. In Modern Persian, however, these characteristics have entirely disappeared, and the Ezafe is merely a NP-internal Linker. I suggest that there is no reason to afford Persian any special priority when evaluating the developmental pathways of the Ezafe particle as a whole within the West Iranian languages. I also discuss an additional development within Northern Kurdish, where the Ezafe particle has become part of the predicate complex, echoing similar developments in a number of unrelated languages.
Extending Graph Neural Networks with Global Features

A common approach to boost the predictive performance of message passing graph neural networks (MPNNs) is to attach additional features to nodes. In contrast, we propose to use expressive global graph features. This is motivated by the limited expressivity of MPNNs resulting in an inability to compute certain global graph properties, like the Wiener index and Hosoya index. Such global graph features are well known in fields like chemoinformatics but seem to be overlooked by the GNN community. We propose an architecture which extends graph embeddings learned by MPNNs with global graph features, for example, topological indices describing the entire graph. Analyzing different global graph features, we show that certain global features like the Wiener index increase the expressivity of MPNNs, while others like the Zagreb indices do not. Our first experiments indicate that adding global graph features improves the performance of MPNNs on molecular benchmark datasets.
Growth performance of tea (Camellia sinensis [L.] Kuntze) as influenced by light intensities on the field in Ibadan, Southwest Nigeria

Tea is one of the most important beverage crops consumed for its antioxidant properties in many parts of the world. Growing tea in Southwest Nigeria is constrained by the warm climate occasioned by high light intensity of the area. Regulation of Light intensity (LI) is necessary for possible cultivation of tea in this area. Information on response of tea to LI in Southwest Nigeria is scanty. Therefore, field experiment was carried out in Cocoa Research Institute of Nigeria Ibadan to assess the growth of two tea cultivars, 143 and 318 under three light intensities: 100% (1.04x105lux), 65% (6.75x104lux) and 45% (4.57x104lux) achieved by using sheds of 0, 1 and 2 palm fronds layers, respectively. The experiment was laid out in randomized complete block design arranged in Split plots with four replications. Data on Number of leaves (NL), Number of branches (NB), Plant height (PH, cm), Stem diameter (SD, cm), Leaf area (LA, cm2) and Dry matter (DM, g) accumulation were obtained following standard procedures, and were analyzed with descriptive statistics and ANOVA at α0. 05. Cultivar 143 performed significantly better than 318 with 88.94NL, 18.73NB, 62.99PH, 0.94SD, 2194LA and 56.38DM under 45% light intensity. The highest NL (84.07), NB (15.86), PH (68.63), SD (1.06) and LA (2885.75) was produced under 45% light, while the least was produced under 100% LI. Total DM ranged from 30.20 g/plant under 100% LI to 65.80 g/plant under 45% LI. In conclusion, optimal vegetative growth and dry matter accumulation of tea cultivar 143 was achieved under 45% LI using sheds of 2 layers of palm fronds.
eCommons@AKU eCommons@AKU

Traditional medicine practitioners (TMPs) are a critical part of healthcare systems in many sub-Saharan African countries and play vital roles in caring for patients with cancer. Despite some progress in describing TMPs’ caring experiences in abstract terms, literature about practice models in Africa remains limited. This study aimed to develop a substantive theory to clarify the care provided by TMPs to patients with cancer in Uganda. This study adhered to the principal features of the modified Straussian grounded theory design. Participants were 18 TMPs caring for patients with cancer from 10 districts in Uganda, selected by purposive and theoretical sampling methods. Researcher-administered in-depth interviews were conducted, along with three focus group discussions. Data were analyzed using constant comparative analysis. The core category that represented TMPs’ meaning of caring for patients with cancer was “Restoring patients’ hope in life through individualizing care. ” TMPs restored patients’ hope through five main processes: 1) ensuring continuity in the predecessors’ role; 2) having full knowledge of a patient’s cancer disease; 3) restoring hope in life; 4) customizing or individualizing care, and 5) improving the patient’s condition/ health. Despite practice challenges, the substantive theory suggests that TMPs restore hope for patients with cancer in a culturally sensitive manner, which may partly explain why patients with cancer continue to seek their services. The findings of this study may guide research, education, and public health policy to advance traditional medicine in sub-Saharan
Trends in Anterior Cruciate Ligament Injury and Recovery in Professional Snowboarders: The Extreme Sport of Snowboardcross

Introduction An anterior cruciate ligament (ACL) tear is a devastating injury for athletes that is predominantly low energy and non-contact in nature. ACL tears are one of the most well-researched injuries in sports, however, scant research has been done on competitive snowboarders. Boardercross is a relatively new sport introduced to the Winter Olympics in 2006. Initially, it entailed four snowboarders racing head-to-head down a course of obstacles in a race to the finish, with the top two riders advancing to the next rounds. It has since expanded to six racers traveling up to 60 mph and jumps up to 100 feet in length in a head-to-head race to the finish. This extreme sport puts its athletes at risk for serious injury, requiring investigation. Purpose Investigate the prevalence of ACL tears in the extreme sport of boardercross, evaluate sport-specific factors that may put athletes at higher risk, and report return to sport data. Methods An expedited IRB approval was obtained. A survey was distributed to athletes via e-mail to national/regional coaches of countries with competitive boardercross teams. Professional coaches distributed the survey and secondarily distributed it to athletes. Results Sixty-six competitive snowboardcross athletes responded to the email surveys 48.5% of respondents had torn their ACL at least once in their career. Of the female respondents, 55.6% suffered at least one ACL tear, and 43.6% of male respondents suffered at least one ACL tear. 31.2% suffered more than one ACL tear during their career. Of those who tore their ACL, 91.3% (p <0.001) tore their front leg. 100.0% of the respondent athletes returned to sport post-ACL reconstruction. Conclusion Professional boardercross racers are at a higher risk of tearing their ACL than other winter sport athletes, including alpine skiers. A predominance of ACL injuries occurred on the front leg during landing from an aerial maneuver. All respondent athletes returned to the sport after injury, with approximately half returning within six months. Although no statistical significance was achieved, the data provided trends on risk factors related to ACL injuries among snowboardcross athletes.