Miracle-dz/UniFAR-FTUs huggingface dataset:
Seroprevalence of viral Hepatitis of enteric (A and E) and parenteral / sexual (B and C) transmission of individuals aged 30 to 70 residents in Salvador-Brazil

Viral hepatitis are still considered as public health problems. Hepatitis caused by HAV and HEV, spread by enteric transmission are, acute infections associated with precarious basic sanitation, inappropriate hygiene and consumption of contaminated food. Hepatitis caused by HBV and HCV viruses transmitted by parenteral /sexual route are associated with chronic diseases and progression to cirrhosis and hepatocarcinoma OBJECTIVES: to estimate the seroprevalence of serological markers of hepatitis A, B, C and E hepatitis, the concomitance of enteric and parenteral / sexual transmission hepatitis in a population aged between 30-70 years and to observe possible relationships with sociodemographic data. METHODS: A cross-sectional study with 650 individuals born between 1945 and 1985 attended at a laboratory in the public health network of Salvador-Brazil. Serological tests included IgG anti-HAV, IgG anti-HEV, IgG anti-HBc, IgG anti-HCV. The volunteers answered a questionnaire containing questions about habits, conducts, previous medical procedures and sociodemographic data. RESULTS: 208 of the participants were men (32.00%) and 442 were women (68.0%) and in the groups younger than 31-50 years (301) and older individuals from 51 to 70 years (349). Seroprevalence of HVA (92.46%), HEV(2.15%), HBV (17.76%) and HCV (3.69%). Of the total population, the concomitant seroprevalence of Ig G anti-HAV and IgG anti-HEV (1.85%) and IgG anti-HBc and IgG anti-HCV (1.38%). With the epidemiological and sociodemographic data it is not possible to associate common risk factors for HAV and / or HEV contact in the study population, however, the association of HEV with the proximity of contact / management with swine reported by some participants can not be excluded. Seroprevalence of HBV and HCV was associated with unprotected sex, sharing of needles and syringes in the older group, and injecting drug use. The group of older and males had a higher prevalence of contact with B and C viruses. CONCLUSION: The contact markers that presented the highest seroprevalence were anti-HAV IgG, followed by the markers for HBV, HCV and HEV. The anti-HCV IgG marker presented a higher prevalence than in the general population and the HEV presented a low prevalence. The group of older individuals and male gender presented a higher seroprevalence of contact with HBV and HCV. Concomitant seroprevalence was low in both enteric and parenteral / sexual transmission hepatitis.
At-sea dumping of dredge spoil: an overview of the Australian policy and legislative framework

ABSTRACT The increase in port development along the Queensland coast, and the associated dredging activity, has led to increased environmental concerns for the health of the Great Barrier Reef (GBR). While such impacts are of particular immediate concern for the GBR region, the issues surrounding dredging and dumping of dredge spoil are common to many other coastal regions in Australia and elsewhere. In this article, we review the current Australian policy and legislation affecting the dumping at sea of dredge spoil and the incentives this creates in terms of minimising damage. We find that the current complex framework may not necessarily provide appropriate incentives to minimise damage once approval has been obtained, although more recent policy interventions may help encourage innovation in more environmentally friendly actions. We also review the potential for other incentive-based management systems to limit environmental damage from dredging, drawing on the experiences in fisheries and marine biodiversity conservation.
Process-Oriented Measurement of Emotion Regulation: General and Specific Associations With Psychosocial Adjustment and Well-Being in (Pre-)Adolescence

The development of emotion regulation (ER) is associated with children’s and adolescents’ psychosocial adjustment and well-being. In this regard, previous studies have examined the role of different ER strategies, which can be characterized as being functional (e.g., reappraisal, problem solving) or dysfunctional (e.g., suppression, rumination). Based on the process model of emotion regulation, the strategies can also be classified according to their temporal position within the emotion generative process, with five families of ER strategies being proposed: situation selection, situation modification, attentional deployment, cognitive change, and response modulation. This study aimed to examine the role of ER for adolescents’ psychosocial adjustment (internalizing and externalizing problems, prosocial behavior) and well-being. First, associations were investigated on a more general level by distinguishing between functional and dysfunctional ER. Second, relations were examined on a more specific level by additionally distinguishing between the five families of ER strategies as suggested in the process model of ER. Questionnaire self-reports of N = 1,727 German children and adolescents (55% girls) aged 9–18 years (M = 13.03, SD = 1.75) collected in schools were analyzed. Path analyses showed that more functional and less dysfunctional ER in general is associated with fewer internalizing and externalizing symptoms, and higher well-being. Prosocial behavior was only positively related to functional but not dysfunctional ER. Analyses of associations on the level of specific categories of ER strategies generally showed a similar pattern, but in part indicated differential associations with the dependent variables: Internalizing problems were particularly associated with functional situation selection, dysfunctional cognitive change, and dysfunctional response modulation. Externalizing problems were associated with functional situation selection and response modulation, as well as numerous dysfunctional strategies, none of which were particularly salient. Similarly, numerous rather than single specific associations emerged between prosocial behavior and the five categories of functional ER strategies. Well-being was particularly associated with functional situation selection and dysfunctional cognitive change. Overall, a more precise assessment of ER, as implemented in this study, could not only advance research in this field, but can also be helpful in planning and evaluating prevention and intervention programs.
Optimisation-based Identification of Situation Determined Cost Functions for the Implementation of a Human-like Driving Style in an Autonomous Car

The acceptance of (partly) autonomous driving systems depe nds critically on the obtained level of anthropomorphic behaviour, consequently the controller d esign has to be derived from the human archetype. Therefore a bilevel optimisation approach is ap plied to obtain the cost function humans minimise by their lateral driving style. The resulting opti mal cost function for a given subject and the traffic situation is used to generate human-like cont rol sequences for the autonomous car. An emotion model accounting for different situations in com bination with a hierarchical guidance architecture is used to allow an online application of the re sults.
Nutritional Ergogenic Aids in Combat Sports: A Systematic Review and Meta-Analysis

Nutritional ergogenic aids (NEAs) are substances included within the group of sports supplements. Although they are widely consumed by athletes, evidence-based analysis is required to support training outcomes or competitive performance in specific disciplines. Combat sports have a predominant use of anaerobic metabolism as a source of energy, reaching peak exertion or sustained effort for very short periods of time. In this context, the use of certain NEAs could help athletes to improve their performance in those specific combat skills (i.e., the number of attacks, throws and hits; jump height; and grip strength, among others) as well as in general physical aspects (time to exhaustion [TTE], power, fatigue perception, heart rate, use of anaerobic metabolism, etc.). Medline/PubMed, Scopus and EBSCO were searched from their inception to May 2022 for randomised controlled trials (RCTs). Out of 677 articles found, 55 met the predefined inclusion criteria. Among all the studied NEAs, caffeine (5–10 mg/kg) showed strong evidence for its use in combat sports to enhance the use of glycolytic pathways for energy production during high-intensity actions due to a greater production of and tolerance to blood lactate levels. In this regard, abilities including the number of attacks, reaction time, handgrip strength, power and TTE, among others, were improved. Buffering supplements such as sodium bicarbonate, sodium citrate and beta-alanine may have a promising role in high and intermittent exertion during combat, but more studies are needed in grappling combat sports to confirm their efficacy during sustained isometric exertion. Other NEAs, including creatine, beetroot juice or glycerol, need further investigation to strengthen the evidence for performance enhancement in combat sports. Caffeine is the only NEA that has shown strong evidence for performance enhancement in combat sports.
Navigating hope and despair in sustainability education: A reflexive roadmap for being with eco-anxiety in the classroom

In this article, we reflect on our experiences of teaching sustainability in management education in an emergent context of increasing and pervasive eco-anxiety. Our collaborative autoethnographic enquiry stemmed from the tensions we experienced in our desire to present a realistic view of the future to students, while still maintaining their (and our) sense of hope and agency. While sustainability in management education has long acknowledged the need to engage learners’ hearts and hands as well as their heads, the challenges of effectively integrating the emotional (heart) dimension in the classroom have remained under-explored in the literature. We develop the findings of our collaborative autoethnography into a framework that provides insights for educators navigating the range of emotional responses evoked in the sustainability in management education classroom. This framework acts as a roadmap, based around five spheres of practice, that will aid sustainability in management education educators in making more conscious and deliberate choices about their teaching practice within the complex context of eco-anxiety.
Comparison of the Mortality and Bleeding Risk of Anticoagulant Doses in COVID-19 Patients: A Systematic Review and Meta-analysis

Anticoagulant therapy becomes critical to preventing further complications caused by the hypercoagulative state in COVID-19 patients. The optimal dose and time-dependent administration of anticoagulants remains unknown. The purpose of this study was to determine the mortality and bleeding risks of anticoagulants administered to COVID-19 patients. We collected data from articles that compared prophylactic and therapeutic anticoagulants in COVID-19 patients recorded online from studies that were published around 2020 to 2021. We were taking the articles from a scientific database such as ScienceDirect, Cochrane, ProQuest, PubMed, and Google Scholar based on the inclusion criteria. Data analysis was conducted using Review Manager Version 5.4. 1 (Cochrane, Copenhagen, Denmark) using Mantel-Haenzel statistical method for categorical data to measure Relative Risk (RR) and 95% Confidence Interval (CI). We use a random-effect analysis model if P for heterogeneity (pHet <0.1) and a fixed-effect analysis model if pHet ≥0.1. Based on time dependent-manner, therapeutic anticoagulant showed no benefit in reducing mortality (RR = 0.69; 95% CI = 0.47 to 1.02). Beside, based on dose-dependent manner, prophylactic anticoagulant was found beneficial to prevent mortality (RR = 0.49; CI 95%; p = 0.02) compared to therapeutic. Therapeutic anticoagulants also showed higher risk of bleeding (RR = 0.27; CI 95%; p < 0.000001) compared to prophylactic. Therapeutic have no significantly benefit over prophylactic dose in reducing mortality rates. Therapeutic anticoagulant has a higher risk of bleeding in patients with COVID-19. Administer prophylactic dose is recommended due to the fewer side effects compared to the therapeutic dose.
Mobility-Focused Physical Outcome Measures Over Telecommunication Technology (Zoom): Intra and Interrater Reliability Trial

Background Rehabilitation provided via telehealth offers an alternative to currently limited in-person health care. Effective rehabilitation depends on accurate and relevant assessments that reliably measure changes in function over time. The reliability of a suite of relevant assessments to measure the impact of rehabilitation on physical function is unknown. Objective We aimed to measure the intrarater reliability of mobility-focused physical outcome measures delivered via Zoom (a commonly used telecommunication platform) and interrater reliability, comparing Zoom with in-person measures. Methods In this reliability trial, healthy volunteers were recruited to complete 7 mobility-focused outcome measures in view of a laptop, under instructions from a remotely based researcher who undertook the remote evaluations. An in-person researcher (providing the benchmark scores) concurrently recorded their scores. Interrater and intrarater reliability were assessed for Grip Strength, Functional Reach Test, 5-Time Sit to Stand, 3- and 4-Meter Walks and Timed Up and Go, using intraclass correlation coefficients (ICC) and Bland-Altman plots. These tests were chosen because they cover a wide array of physical mobility, strength, and balance constructs; require little to no assistance from a clinician; can be performed in the limits of a home environment; and are likely to be feasible over a telehealth delivery mode. Results A total of 30 participants (mean age 36.2, SD 12.5 years; n=19, 63% male) completed all assessments. Interrater reliability was excellent for Grip Strength (ICC=0.99) and Functional Reach Test (ICC=0.99), good for 5-Time Sit to Stand (ICC=0.842) and 4-Meter Walk (ICC=0.76), moderate for Timed Up and Go (ICC=0.64), and poor for 3-Meter Walk (ICC=–0.46). Intrarater reliability, accessed by the remote researcher, was excellent for Grip Strength (ICC=0.91); good for Timed Up and Go, 3-Meter Walk, 4-Meter Walk, and Functional Reach (ICC=0.84-0.89); and moderate for 5-Time Sit to Stand (ICC=0.67). Although recorded simultaneously, the following time-based assessments were recorded as significantly longer via Zoom: 5-Time Sit to Stand (1.2 seconds), Timed Up and Go (1.0 seconds), and 3-Meter Walk (1.3 seconds). Conclusions Untimed mobility-focused physical outcome measures have excellent interrater reliability between in-person and telehealth measurements. Timed outcome measures took approximately 1 second longer via Zoom, reducing the reliability of tests with a shorter duration. Small time differences favoring in-person attendance are of a similar magnitude to clinically important differences, indicating assessments undertaken using telecommunications technology (Zoom) cannot be compared directly with face-to-face delivery. This has implications for clinicians using blended (ie, some face-to-face and some via the internet) assessments. High intrarater reliability of mobility-focused physical outcome measures has been demonstrated in this study.
Yurt Invited: Combining Tourists and Stakeholders Perceptions of Sustainable Community-Based Tourism in Central Asia

Community-based tourism represents an opportunity for sustainable socioeconomic development, helping local populations to emerge out of lower living conditions. This paper investigates the perceptions of tourists and stakeholders engaged in Community-Based Tourism (CBT) in Central Asian countries (including Kazakhstan, Uzbekistan, Kyrgyzstan, Tajikistan, and Turkmenistan) as an opportunity for sustainable development. This study’s purpose is to point out the usefulness of a combination approach of stakeholders’ and tourists’ perceptions to address the opportunities of CBT that can improve the quality of life of the tourism community in Central Asia by identifying the pitfalls of practices and determining challenges for tourism policy. Using a mixed-method approach, two complementary methodologies are simultaneously conducted. (1) An in-depth interview approach with sixteen selected experts in the region was processed with semantic network analysis for the definition of the main challenges and opportunities facing CBT as an enabler of sustainable development, considering the perceptions of sustainability from the point of view of stakeholders. (2) An online survey involving one hundred twenty-five tourists to the region was carried out to focus on tourists’ perceptions of sustainability. A structural equation modelling technique was used to identify the influence of tourists’ sustainability preferences and their involvement with local communities on sustainability perceptions. The results highlight the benefits the community receives, as well as future opportunities to obtain more advantages from tourism practices within the scope of sustainable tourism planning.
A proposed model of m-learning for technical and Vocational Education Training (TVET) students

Latest educational technology that called mobile learning or m-learning is a new style of learning as the development of mobile technology which can help to hold attention and make students more on self-study at anywhere and anytime. The paper focuses on a proposed model of m-learning for Technical and Vocational Education and Training (TVET) students in Malaysia. Development of the model is based on the user requirements from the TVET students in accordance to three aspects; device, user and social technology. The proposed model will be used as a guideline in the development of m-learning application which can improve teaching and learning quality and also motivate students to have interest on the learning.
The Role of Mitochondria in Metabolic Syndrome–Associated Cardiomyopathy

With the rapid development of society, the incidence of metabolic syndrome (MS) is increasing rapidly. Evidence indicated that patients diagnosed with MS usually suffered from cardiomyopathy, called metabolic syndrome–associated cardiomyopathy (MSC). The clinical characteristics of MSC included cardiac hypertrophy and diastolic dysfunction, followed by heart failure. Despite many studies on this topic, the detailed mechanisms are not clear yet. As the center of cellular metabolism, mitochondria are crucial for maintaining heart function, while mitochondria dysfunction plays a vital role through mechanisms such as mitochondrial energy deprivation, calcium disorder, and ROS (reactive oxygen species) imbalance during the development of MSC. Accordingly, in this review, we will summarize the characteristics of MSC and especially focus on the mechanisms related to mitochondria. In addition, we will update new therapeutic strategies in this field.
Which play is better? Different play types and development of executive functions in early childhood

ABSTRACT In this study we aimed to compare the contribution of each play type to the development of different EFs components: shifting, working memory (visuospatial and auditory) and inhibition (two aspects of cognitive inhibition and physical inhibition). Following a preliminary examination of EFs was the intervention, which consisted of 14 play sessions for 20–30 min twice a week. Participants (n = 199, 46.7% females), aged from 52 to 69 months (M = 60.79; SD = 4.10) were assigned to one of five experimental groups: three types of role play (free role play; adult-directed play; child-directed play), digital games, games with rules (board games). All the measured EFs significantly increased following the digital games’ intervention. In ‘Games with rules’ and ‘Adult-directed play’ intervention groups, significant changes were registered in 5 (out of 6) measures of EFs. In the ‘Free play’ and ‘Child-directed play’, significant changes were found in 4 measures of EFs. Differential effect of play on EFs components is discussed. These results demonstrate the importance of play for EFs development and given the differential effect of play types, those can be applied based on the children’s needs.
Embryological Characteristics of Human Oocytes With Agar-Like Zona Pellucida and Its Clinical Treatment Strategy

Zona pellucida (ZP) abnormalities are the cause of low fertility or infertility, agar-like ZP is more common in abnormal ZP. The purpose of this exploration is to systematically analyze the fertilization competence of agar-like ZP oocytes, the development characteristics of subsequent embryos as well as the results of embryo transfer, aiming to explore effective clinical treatment strategies. A total of 58 patients with agar-like ZP were set as the case group and the control group involved 3866 patients, in which the patients’ oocytes presented normal ZP. BMI, basal hormone levels, and hormone levels were similar in both groups. The case patients suffered significantly longer infertility years than control (p<0.05), and most patients were diagnosed with pelvic inflammatory diseases. A distinct difference was observed in the structure of oocyte corona cumulus complexes between the two groups. The embryo development parameters, which include the rates of cleavage, high-quality embryo, blastocyst, and high-quality blastocyst in the case group were greatly lower than that in the control group (p<0.05). The rates of cumulative clinical pregnancy and live birth were comparable between the two groups. In the subsequent follow-up, thirty-four of the 58 patients receiving intracytoplasmic single sperm injection (ICSI) or early rescue ICSI (R-ICSI) treatment successfully gave birth to babies, and all of the newborns were with no neonatal defects. In addition, the fertilization rate of the R-ICSI group was significantly lower than that of the ICSI group (p<0.05). The occurrence of agar-like ZP impairs the development competence of human oocytes, however, the human oocytes with agar-like ZP can develop into healthy offspring, and an ICSI regimen is the optimal treatment strategy for them.
Peculiarities of art management in a digital context – case study of Poland

The digitalisation of the aesthetic experience affects the level of artistry and creativity transfer by the artwork and the quality of participation in the arts. Due to cultural differences between Poles other countries’ citizens in perception qualities, this study assesses the effect of the participation form (in-real or digital) in the aesthetic situation by receivers on artistry and creativity potential. The quality of participation in five arts types (musical, performing, literary, audio-visual, visual) was assessed using ten criteria. Data analysis, based on a worldwide sample (38 countries, n = 221). The participation form in arts determines participation quality in the aesthetic situation differently by Polish and non-Polish receivers. Furthermore, there are noteworthy cultural variances among Polish and non-Polish art receivers of particular types of arts and particular forms of participation in arts. The study outcomes may interest: art creators looking for the optimal way of delivering artworks among receivers from Poland and other countries; art managers and marketers for deeper understanding of Polish art receivers’ viewpoints and their preferences about participation in arts in-real or digitally; art receivers to compare their judgement about the participation ways in arts with the preferences of Polish art receivers. The first attempt in the literature assessing the quality of the participation in the aesthetic situation regarding the form of participation between Polish and non-Polish societies.