Miracle-dz/UniFAR-FTUs huggingface dataset:
Ischemic conditioning in organ transplantation

Organ transplantation comes with the inevitability of ischemia reperfusion (IR) injury and the potential for resultant graft dysfunction and acute rejection. Such episodes may limit both graft and patient survival. Ischemic conditioning is a simple, safe and virtually cost-neutral intervention that induces a systemic protective reflex which may protect against IR injury. This review summarizes the current evidence for an effect of ischemic conditioning strategies in the clinical setting of organ transplantation.
Multiple Sclerosis Patients in Saudi Arabia: Prevalence of Depression and its Extent of Severity

Background Multiple sclerosis (MS) is a serious chronic autoimmune disorder of the central nervous system of unknown etiology. MS-related depression is a common mood disorder recognized within the medical community. However, their association is ambiguous, underdiagnosed, undertreated and less reported. Objectives The study aimed to estimate the point prevalence and severity of depression among multiple sclerosis patients in Saudi Arabia. Materials and methods We conducted an observational cross-sectional study among multiple sclerosis patients in Riyadh region, Saudi Arabia. Patients filled demographic data and Patient Health Questionnaire-9 (PHQ-9) to determine depression. Those who did not meet the age, disease duration, and regular follow-up eligibility criteria were excluded from the study. Results We enrolled 238 MS patients in the study, male patients represented 39.1% (n = 93) while females accounted for 60.9% (n = 145) (male:female ratio 0.64). The mean age of the study population was 32.07 ± 7.93 years. The mean duration of the disease was 7.06 ± 4.7 years. We determined that 89.9% (n = 214) of the patients showed mild to severe depression symptoms (55.46% of the females, and 34.4% of the males; p = 0.474). We further found that 37.39% (n = 89) and 65.13% (n = 155) of the depressed patients were unemployed (p = 0.039) and were non-smokers (p = 0.097) respectively. Furthermore, depression severity is significantly associated with education (p = 0.005). Conclusion High levels of depression symptoms were found among MS patients in Saudi Arabia. The relationship between MS and psychiatric conditions exists despite the uncertainty of its pathogenesis. Further longitudinal studies should be carried out to obtain more valid outcomes. Neurologists treating MS patients can play a role in studies related to the condition by investigating depressive symptoms actively and providing the data.
CIA_A_211549 1353..1360

Anna Jurczak 1 Małgorzata Szkup 2 Krzysztof Safranow 3 Agnieszka Samochowiec 4 Sylwia Wieder-Huszla 1 Joanna Owsianowska 1 Elżbieta Grochans 2 1Department of Clinical Nursing, Pomeranian Medical University in Szczecin, Szczecin, Poland; 2Department of Nursing, Pomeranian Medical University in Szczecin, Szczecin, Poland; 3Department of Biochemistry, Pomeranian Medical University in Szczecin, Szczecin, Poland; 4Department of Clinical Psychology, Institute of Psychology, University of Szczecin, Szczecin, Poland Background: Psychological stress is a factor which predisposes people to many somatic and mental disorders. Women are at a significantly higher risk of stress than men, and their reactions to stress are stronger. Personality traits are thought to play a special role in the psychology of stress and may be crucial for the choice of a stress-coping strategy. Considering that stress is so common in everyday life, an attempt to understand how stress-coping styles are related to personality and genetic factors acquires special significance. Purpose: The aim of this study was to analyze stress-coping styles and personality traits in healthy late reproductive age women with regard to genetic factors. Patients and methods: The study involved 345 healthy late reproductive age women from northwest Poland, whose mean age was 42.3±4.5 years. The study was conducted using The Coping Inventory for Stressful Situations, The Neuroticism-Extraversion-Openness Five– Factor Inventory, and genetic testing. Results: There were neither statistically significant relationships between personality traits and the genotype distribution of the 30-bp VNTR polymorphism in the MAO-A promoter region, nor between stress-coping styles and the genotype distribution of the 30-bp VNTR polymorphism in the MAO-A promoter region. Conclusion: Based on the results, all personality traits statistically significantly correlated with the choice of task-oriented coping and emotion-oriented coping. Some of personality traits are genetically determined. The choice of a stress-coping style was significantly related to personality traits. A direct influence of genetic factors on the choice of a stress-coping style was not confirmed in our study.
Immediate postpartum family planning preferences among couples in Rwanda

INTRODUCTION: Improving access to modern methods of contraception and decreasing the unmet need for contraception are important in working toward decreasing the rates of unintended pregnancy. This study was designed to obtain a greater understanding of desire for contraception among women and their partners in Rwanda and assess factors associated with uptake of contraception in the immediate postpartum period. METHODS: The cross-sectional, family planning attitude and practices survey was conducted among postpartum women and their partners prior to discharge from the hospital. The study was conducted at two large referral hospitals providing maternity care in Rwanda. Data was aggregated and we performed comparison on postpartum contraception attitude and practices among women and partners and logistic regression. RESULTS: One hundred and five patients and thirty-one partners of patients completed the questionnaire. Immediately postpartum, 47.6% of women desired contraception, while only 11.4% received postpartum family planning (PPFP) prior to discharge. Factors associated with a patient receiving PPFP immediately postpartum include: discussing PPFP with provider during antenatal care (p = 0.02), discussing with partner immediately postpartum (p = 0.003), and discussing with provider immediately postpartum (p = 0.01). CONCLUSION: These findings indicate a gap in postpartum contraception counseling and uptake in Rwanda.
Characteristics of Hydrothermally Treated Beeswax Amber

lions of years ago when sap from ancient trees hardened and fossilized. Scientists, gemologists, and collectors treasure amber that contains suspended insects or assorted plant fragments, creating a fascinating time capsule (Ross, 2010). Amber has become increasingly popular in the jewelry trade. It is usually translucent to opaque, and its opacity is caused by the reflection and scattering of incident light by an abundance of internal tiny bubbles. “Beeswax,” a term commonly used in the Chinese gem trade, refers to amber that is semi-translucent to opaque with greasy luster. Beeswax accounts for about 60% of natural amber production globally. Due to the saying “Millennium amber, million years beeswax” in the Chinese gem market, many Chinese consumers mistakenly believe that beeswax takes much longer to form than amber. This misimpression has driven demand for beeswax and significantly raised its price. Among beeswax, the “chicken-fat” yellow variety is highly desired in China for its vivid color, but limited in global production. It is worth noting that in the international rough amber trade, transparent and opaque materials are usually mixed together for sale, just as they are mixed together in nature. There is usually a layer of weathered skin on the surface of both transparent and opaque rough amber, making it impossible to choose them individually by hand under normal lighting. There is no price difference between the two. Quality is judged according to weight, size, shape, and impurities. Due to the popularity of beeswax in the Chinese market, however, amber processing enterprises have preferred to purchase and store rough beeswax materials, artificially driving up the price of the rough ma-
Aggregatibacter actinomycetemcomitans in Down's syndrome children.

OBJECTIVES To investigate the presence of Aggregatibacter actinomycetemcomitans (Aa) in Down's syndrome (DS) children in comparison with age-matched normal children and to determine if Aa was acquired during childhood in DS individuals. STUDY DESIGN 60 DS children and 60 healthy children participated in this cross-sectional study. Both groups were matched regarding gender and age and were equally selected from public schools/non-fee paying centers and private schools. Subgingival plaque sample were obtained and analyzed for Aggregatibacter actinomycetemcomitans (Aa). Traditional cultivation method was used on a selective medium "modified malachite green vancomycin agar " RESULTS A significantly higher percentage ofDS children had Aa in their subgingival plaque compared to their healthy counterparts (Chi square = 8.78, p = 0.003). Although Aa was acquired by children as early as 5 years of age in both groups, no association was found between the occurrence of Aa and age. CONCLUSIONS Higher proportion ofDS children acquired Aa compared to their healthy controls and Aa is acquired by children as early as 5 years of age.
The Outcome of Early and Intensive Inpatient Rehabilitation of Paraplegic Patient Following Meningioma Resection Complicated with Post Surgery Contralateral Intracerebral Haemorrhage

Aim: This study was conducted to compare the outcome of an early and intensive inpatient rehabilitation of paraplegic patient both sides, the side that affected by brain tumour excision and the side that affected by haemorrhage lesion. Methodology: The patient was a 43-year-old woman presenting with right parasagittal meningioma attached to the posterior third of the superior sagittal sinus (SSS) and complicated with post-surgery contralateral intracerebral haemorrhage. After that, patient developed a complete paraplegia. She received 8 weeks of intensive inpatient rehabilitation and the intervention was reviewed in 4th week post-surgery and in the 8th week at the time of discharge. Results: The outcome was variable comparing to the both sides. In the 4th week post-surgery, the body side affected by tumour resection improved with muscles power graded against gravity as follows: hip flexor was 1/5 improved to 3/5, hip adductor was 2-/5 improved to 3/5, hip extensor was 1/5 improved to 3+/5, hip abductor was 0/5 improved to 3-/5, knee flexor was 1/5 improved to 3/5, knee extensor was 1/5 improved to 4-/5, ankle dorsiflexors and plantar flexors were 0/5 improved to 3/5 while the side affected with haemorrhage lesion exhibited slower recovery with muscles power graded with gravity elimination except hip extensor and knee extensor which improved to 3/5, the muscles power as follows: hip flexor was 1/5 improved to 2+/5, hip abductor was 0/5 improved to 2-/5, hip adductor was 2-/5 improved to 2/5, knee flexor was 1/5 improved to 2/5, ankle dorsiflexor was 0/5 improved to 2-/5 and ankle plantar flexor was 0/5 improved to 2/5. In the 8th week at the time of discharge, there were no significant differences in muscles power of both sides except the hip extensors and abductors and knee extensors muscles which found to have minimum differences. Conclusion: This case report is consistent with previous studies that proven brain tumour patient can achieve a good functional outcome and have short rehabilitation length of stay than stroke patients.
Bone substitute with Cerasorb in orthopedic surgery , traumatology and hand surgery

Between 1997 and 2013 a total number of 106 cases with the indications tumor (most frequent diagnosis: enchondroma), rheumatism, and trauma were included in a prospective monocentre study design. In most cases hand surgery was performed. All patients were treated with Cerasorb, a synthetic resorbable bone regeneration material. Autologous spongious bone was administered additionally in 8 surgical operations, in 59 cases platelet rich plasma (PRP) was used. In the long term resorption of the ceramic material and simultaneous formation of vital autologous bone took place regularly. There were no clinical irregularities, allergic reactions or potential complications documented due to the material. No major differences between the 3 indication groups regarding resorption of Cerasorb and bone healing could be observed. The additional use of autologous spongious bone or PRP showed no further improvement of the bone healing and regeneration process.
RETAIL SERVICE QUALITY, PRICES, AND SHOPPING CENTER AMENITIES: PRELIMINARY EVIDENCE FROM HAVANA

One might argue that a disproportionate amount of research examining the tepid market reforms in postSoviet Cuba emphasizes the island’s second economy (Pérez-López 1995), cuentapropistas (Peters and Scarpaci, 1998) and related gray areas of commerce and consumption (Weinreb, 2009). A paradigmatic assumption driving this research is that the ever-resourceful Cuban will make ends meet (resolver, solucionar) through whatever means possible. Necessity drives many Cubans to the black market. Even contemporary assessments about the island’s incremental liberalizations are dour: microenterprises will lead only to a sort of “kioskization” of the service sector, therefore stifling any real economic growth. While a good deal of remittances fuels those sectors of the economy, state-run retailing continues to absorb hard currency (Morales 2008). Although the number of retail established tumbled from around 60,000 in 1959 to around 4,000 in the early 1990s, the trend of retail outlets is on the uptick. Less is known, however, about the ways Cuban consumers interact with these multi-billion dollar enterprises.
Moisture rainout fraction over the Indian Ocean during austral summer based on ratios of surface seawater, rainwater at latitude range of

K Prasanna* , Prosenjit Ghosh, S K Bhattacharya, P Rahul, Kei Yoshimura and N Anilkumar Birbal Sahni Institute of Palaeosciences, Lucknow 226 007, India. 2Centre for Earth Sciences, Indian Institute of Science, Bengaluru, India. 3Divecha Centre for Climate Change, Indian Institute of Science, Bengaluru, India. 4Atmosphere and Sea Research Institute and Institute of Industrial Science, The University of Tokyo, Tokyo, Japan. 5National Centre for Antarctic and Ocean Research, Vasco da Gama, Goa, India. *Corresponding author. e-mail: naiduprasanna@gmail.com
Environmental Satisfaction, Residential Satisfaction, and Place Attachment: The Cases of Long-Term Residents in Rural and Urban Areas in China

Drawing on literature from environmental psychology and urban planning, this study evaluates the relationships between environmental satisfaction, residential satisfaction, and place attachment in the context of both rural and urban areas in China. A field survey was carried out with 490 valid questionnaires collected in rural areas and 420 from urban areas in China. Partial least squares path modeling was applied for testing the relationships between the three main constructs. The results indicate a significant mediating role of residential satisfaction between environmental satisfaction and place attachment, suggesting the importance of residential satisfaction in residents’ attachment-building to place. This study also found significant differences between rural and urban contexts with the mediating effect of residential satisfaction being absent from the rural sample.
Response of Optically Transparent pH Sensing Films to Temperature and Temperature Variations

There are numerous applications for thin films based chemical pH sensors, in such areas as biomedical, military, environmental, food, and consumer products. pH sensitive films fabricated through the ionic self-assembled monolayers technique were made of polyelectrolyte polyallylamine hydrochloride and the water-soluble organic dye molecule Direct Yellow 4. The films were monitored in various environmental conditions and for selected periods, at temperatures varying between −13.7 and 46.2 °C. Absorbance measurements and atomic force microscopy performed before and after thermal treatment indicate that for optimized thickness and composition the films maintain their functionality and are not affected by long-term exposure at these temperatures.
Disseminated articles through digital social channels and its relation with metrics of academic impact

In order to explore the relationship between the dissemination of articles through social channels and the metrics of academic impact, digital methods were used to analyze a sample of 29 808 articles from PLoS ONE and 10 718 articles from Scientific Reports. The quantitative research found that there is a very weak correlation between the impact of an article on digital social channels and the number of citations, and that social impact indicators better predict the number of times the article is read than the citation volume.
Game On: The Relationship Between Media Exposure, Demographics, and Perceptions of Campus Safety

Concealed carry supporters tend to be male, white, conservative, southern, and own guns (Cavanaugh, Bouffard, Wells, & Nobles, 2012). Furthermore, their perceptions of campus safety are not as affected by exposure to fictional or non-fictional (news) media depicting gun violence in academic settings compared to those without such ―pro-carry‖ demographics (O‘Donnell, Carter, Goodmon, Zunic, Smith, & Parisi, 2018). The current purpose was to determine if the relationship between media type exposure, demographics, and perceptions of campus safety generalized to video game exposure as another fictional depiction of campus shootings. Results indicated support for media influence on perceptions of college campus safety. Specifically, news or video game exposure resulted in greater campus safety concern. Results are discussed in terms of how the effect of media type was related to prior levels of pro or anti-carry demographics.
Empires: The Nonlocal Properties of Quasicrystals

In quasicrystals, any given local patch—called an emperor—forces at all distances the existence of accompanying tiles—called the empire—revealing thus their inherent nonlocality. In this chapter, we review and compare the methods currently used for generating the empires, with a focus on the cut-and-project method, which can be generalized to calculate empires for any quasicrystals that are projections of cubic lattices. Projections of non-cubic lattices are more restrictive and some modifications to the cut-and-project method must be made in order to correctly compute the tilings and their empires. Interactions between empires have been modeled in a game-of-life approach governed by nonlocal rules and will be discussed in 2D and 3D quasicrystals. These nonlocal properties and the consequent dynamical evolution have many applications in quasicrystals research, and we will explore the connections with current material science experimental research.
Credit Spreads, Business Conditions, and Expected Corporate Bond Returns

Using an aggregate credit spread index, we find that it has substantial predictive power for corporate bond returns over short and long horizons. The return predictability is economically and statistically significant and robust to various controls. The credit spread index and its components have more predictive power for bond returns than conventional default and term spreads. When decomposing the credit spread index into investment- and speculative-grade components, the latter has more predictive power for future bond returns. The source of the index’s predictive power is from its ability to forecast future economic conditions.
Targeting GRP78-dependent AR-V7 protein degradation overcomes castration-resistance in prostate cancer therapy

Rationale: Androgen receptor splice variant 7 (AR-V7) is a leading cause of the development of castration-resistant prostate cancer (CRPC). However, the regulation and function of AR-V7 at levels of post-translational modifications in prostate cancer therapy remain poorly understood. Here, we conducted a library screen of natural products to identify potential small molecules responsible for AR-V7 protein degradation in human prostate cancer cell lines. Methods: A natural product library was used to screen the inhibitor of AR-V7. Co-IP and biomass spectrum assays were used to identify the AR-V7-interacting proteins, whereas western blot, confocal microscopy, RNA interfering, and gene transfection were used to validate these interactions. Cell viability, EDU staining, and colony formation assays were employed to detect cell growth and proliferation. Flowcytometry assays were used to detect the distribution of cell cycle. Mouse xenograft models were used to study the anti-CRPC effects in vivo. Results: This screen identified rutaecarpine, one of the major components of the Chinese medicine Evodia rutaecarpa, as a novel chemical that selectively induces AR-V7 protein degradation via K48-linked ubiquitination. Mechanically, this effect relies on rutaecarpine inducing the formation of a GRP78-AR-V7 protein complex, which further recruits the E3 ligase SIAH2 to directly promote the ubiquitination of AR-V7. Consequently, the genetic and pharmacological activation of the GRP78-dependent AR-V7 protein degradation restores the sensitivity of castration-resistant prostate cancer to anti-androgen therapy in cell culture and animal models. Conclusions: These findings not only provide a new approach for overcoming castration-resistance in prostate cancer therapy, but also increase our understanding about the interplay between molecular chaperones and ubiquitin ligase in shaping protein stability.
Nutritional and anti-nutritional composition of Diospyros mespiliformis and Hyphaene petersiana fruits from Namibia

Wild fruits play an important role in the well-being of many people in Namibia. Two wild fruits namely, Diospyros mespiliformis Hochst. ex A. DC (Ebenaceae) and Hyphaene petersiana Klotzsch ex Mart. (Arecaceae) were analyzed for proximate, nutritional and anti-nutritional composition. The proximate results showed that the moisture content ranged between 8.3-12%, crude fat (0.1-0.45 mg/g), crude protein (1.6-2.6 mg/g), carbohydrate (4-5.3 mg/g), and ash content (3.3-6 mg/g). The mineral contents of the studied fruits were: calcium (5.01-20.33 mg/kg), potassium (94.8-245.94 mg/kg) and sodium (2.80-11.65 mg/kg). Trace elements such as iron (0.14-2.44 mg/kg) and zinc (0.17-0.19 mg/kg) were also detected. Anti-nutrient values were lower than those for established toxic values. High levels of saponins (2.46 mg/g), tannins (0.10 mg/g) and phytate (0.12 mg/g) were detected in H. petersiana pulp, and oxalate (0.04 mg/g) was detected in D. mespiliformis pulp. However, these anti-nutritional factors were within established safe consumption limits. The results of this study signify that the two fruits have high concentrations of essential minerals and low anti-nutrients; thus their consumption is recommended, especially in poor settings.
Independent Directors and Organizational Performance: New Evidence from A Meta-Analytic Regression Analysis

This study not only revisits, from a meta-analytic perspective, the influence of firms’ boardroom independence on corporate financial performance, but also addresses the way that countries’ social and institutional contexts moderate that connection. A meta-regression covering 126 independent samples reveals that firms’ boardroom independence has a positive and negative effect on accounting and market-based measures of corporate financial performance, respectively. Further analyses reveal that while the firms’ board independence-financial performance connection is stronger in non-communitarian societies, that relationship becomes weaker in countries with greater developed mechanisms to protect the interest of minority investors. These results are robust to different model specifications and to the presence of a set of methodological control variables. Our results are of outstanding relevance for companies’ board composition processes by suggesting the way that corporations should actively re-balance the proportion of independent directors across different social and institutional contexts to ensure their financial success.