Miracle-dz/UniFAR-FTUs huggingface dataset:
Biomarkers of CD 4 + T-cell activation as risk factors for tuberculosis-associated immune reconstitution inflammatory syndrome

HAL is a multi-disciplinary open access archive for the deposit and dissemination of scientific research documents, whether they are published or not. The documents may come from teaching and research institutions in France or abroad, or from public or private research centers. L’archive ouverte pluridisciplinaire HAL, est destinée au dépôt et à la diffusion de documents scientifiques de niveau recherche, publiés ou non, émanant des établissements d’enseignement et de recherche français ou étrangers, des laboratoires publics ou privés. Biomarkers of CD4+ T-cell activation as risk factors for tuberculosis-associated immune reconstitution inflammatory syndrome. Lisa A Chakrabarti, Céline Boucherie, Florence Bugault, Marie-Christine Cumont, Caroline Roussillon, Guillaume Breton, Olivier Patey, Geneviève Chêne, Laura Richert, Olivier Lortholary, et al.
Training Software Engineers Using Open-Source Software: The Students' Perspective

Software Engineering courses often emphasize teaching methodologies and concepts in small and controlled environments over teaching, say, maintenance aspects of full-fledged real software systems. This decision is partly justified due to the difficulty of bringing to the context of a classroom a real software project. The widespread presence of open source projects, however, is contributing to alleviating this problem. Several instructors have already adopted contributions to open source projects as part of their evaluation process, and these instructors reported many benefits, including the improvement on students' technical and social skills. However, little is known about the students' perceptions regarding the need to contribute to an open source project as part of a Software Engineering course. To better understand the students' challenges, benefits, and attitudes, we conducted 21 semi-structured interviews with students who took these courses in five different Brazilian universities. We also enriched this data with an analysis of commits performed in the repositories that students contributed to. We observed that even though some instructors chose the open source projects to students to work themselves, some students and even the open source community participated in the process of choosing projects and tasks. Students' contributions varied concerning both complexity (measured by the number of additions, deletions, and edited files) and diversity (measured regarding the different programming languages used). Among the benefits, students reported improving their technical skills and their self-confidence. Finally, some students found extremely important for instructors' being involved with open source initiatives (extra-classroom).
Changing Australian leisure mobilities in the COVID-19 pandemic: exploring the role of automobilities

ABSTRACT The COVID-19 pandemic continues to affect leisure mobilities globally. In Australia, the pandemic has radically influenced the mobilities of domestic tourists, with travellers subjected to dynamic and intermittent restrictions on both intrastate and interstate movement since March, 2020. This paper reports on the findings of a study conducted between June and July 2020 that explored Australians’ intentions to participate in tourism as COVID-19 leisure travel restrictions eased. It reveals that the participants sought to shift from modes of transport that involve high risks of exposure to other tourists, including cruise ships and air travel, to private, smaller-scale forms of leisure mobility such as cars and campervans. The paper draws from this trend to offer recommendations that champion both the experiential qualities of tourist automobilities and the positioning of private vehicles as temporary facilitators of safer mobilities that may also support wellbeing. These recommendations are afforded additional significance by the opportunities they imply for the stimulation of regional tourism economies severely affected by the unstable and volatile mobilities of the COVID-19 pandemic.
Usage Of Duckweeds Mixture For Treatment Of Leachate : II . COD , pH and EC

Received: 03.08. 2012, Accepted: 22.02. 2013 _____________________________________________________________________________________ Özet. Bu çalışmada, sızıntı suyu arıtımı için Lemna gibba L. , Lemna minor L. , Spirodela polyrrhiza ve Wolffia arrhiza’dan oluşan su mercimekleri karışımı kullanılmış ve bitkili kesikli sistemde KOİ, pH ve elektriksel iletkenlik (Eİ) değişimleri araştırılmıştır. Deneysel çalışmalar, 4 adet reaktörde oda sıcaklığında gerçekleştirilmiştir. En yüksek KOİ giderim verimi, 5 ve 10 cm derinlikteki reaktörlerde sırasıyla %62,2 ve %60,1 olarak tespit edilmiştir. Başlangıçta 7,91 değerinde olan pH, farklı hidrolik bekletme sürelerinde 7,91-8,49 arasında olmuştur. Başlangıçta 5,59 mS/cm değerinde olan elektriksel iletkenlik, en yüksek 9,46 mS/cm değerine ulaşmıştır.
Perceived Organizational Support Terhadap Komitmen Organisasi dan Kinerja Karyawan

PT. Panca Mitra Multi Perdana is a company engaged in the export-import field. The production division is a division with a large workload and generally has the highest employee turnover compared to other divisions. Employee turnover can be suppressed by increasing perceived organizational support. This is because perceived good organizational support is directly proportional to organizational commitment and employee performance. This study aims to determine the effect of perceived organizational support on organizational commitment and employee performance on production division employees at PT. Panca Mitra Multi Perdana, located in Situbondo. This research uses causal quantitative research. The sample in this study amounted to 100 employees of the production division at PT. Panca Mitra Multi Perdana, located in Situbondo. Samples were selected using the purposive sampling method. Research data were analyzed using the Partial Least Square (PLS) method. The results showed that perceived organizational support had a positive and significant effect on organizational commitment with an R-Square value of 0.9123 (91.23%). Perceived organizational support has a positive and significant effect on employee performance with an R-Square value of 0.8997 (89.97%).
Event-Triggered Quantized Control for Input-to-State Stabilization of Linear Systems With Distributed Output Sensors

We study output-based stabilization of linear time-invariant systems affected by unknown external disturbances. The plant outputs are measured by a collection of distributed sensors, which transmit their feedback information to the controller in an asynchronous fashion over different digital communication channels. Before transmission of measurements is possible quantization is needed, which is carried out by means of dynamic quantizers. To save valuable communication resources, the transmission instants of each sensor are determined by event-triggering mechanisms that only depend on locally available information. We propose a systematic methodology for the joint design of the (distributed) dynamic quantizers and the event-triggering mechanisms ensuring an input-to-state stability property of a size-adjustable set around the origin. Moreover, the proposed approach prevents the occurrence of Zeno behavior on the transmission instants and on the updates of the quantizer variable thereby guaranteeing that a finite number of data is transmitted within each finite time window. The tradeoff between transmissions and quantization is characterized in terms of the design parameters. The method is feasible for any stabilizable and detectable linear plant. The systematic design procedure and the effectiveness of the approach are illustrated on a numerical example.
Adherence to a healthy lifestyle in relation to colorectal cancer incidence and all‐cause mortality after endoscopic polypectomy: A prospective study in three U.S. cohorts

It remains unknown whether maintenance of a healthy lifestyle after endoscopic polypectomy could still confer benefit for colorectal cancer (CRC) incidence and mortality. In this study, we defined a healthy lifestyle score based on body mass index, smoking, physical activity, alcohol consumption and diet (range, 0‐5). We used Cox proportional hazards regression to estimate the hazard ratios (HRs) for the associations of healthy lifestyle score and individual lifestyle factors with CRC incidence and all‐cause mortality. During a median of 10 years of follow‐up of 24 668 participants who underwent endoscopic polypectomy, we documented 161 CRC cases and 4857 all‐cause deaths. A higher healthy lifestyle score after endoscopic polypectomy was associated with lower risk of CRC and all‐cause mortality. Compared with individuals with 0 to 1 healthy lifestyle factors, those with 2, 3 and 4 to 5 healthy lifestyle factors had a HR for CRC risk of 0.86 (95% confidence interval [CI], 0.60‐1.24), 0.73 (95% CI, 0.47‐1.14) and 0.52 (95% CI, 0.27‐1.01), respectively (Ptrend = .03). The corresponding HR (95% CI) for all‐cause mortality was 0.83 (95% CI, 0.76‐0.90), 0.63 (95% CI, 0.56‐0.70) and 0.56 (95% CI, 0.48‐0.65), respectively (Ptrend < .0001). In the joint analysis of pre‐ and postpolypectomy periods, patients with a healthy postpolypectomy lifestyle had a lower incidence of CRC regardless of their prepolypectomy exposure, whereas those with a healthy lifestyle in both periods had a lower mortality than those with an unhealthy lifestyle in either period. In conclusion, adherence to a healthy lifestyle after polypectomy may confer significant benefit for CRC prevention and reduction in all‐cause mortality.
THERISKASSESSMENTOFADVERSEEVENTS OFNURSINGACTIVITIESASTHEELEMENT OFQUALITYMANAGEMENTINHEALHCARE

Received: 21 December 2014 Abstract Accepted: 12 January 2015 The purpose of the paper is to present MedCARVER+Shock method and Pareto analysis and its usability for the risk assessment of adverse events of nursing activities. 888 activities carried out by all 190 nurses working at the District Hospital X located in Poland were taken into account. During the research the qualitative approach was used. As the result sixteen groups of nursing activities causing the highest risk of adverse events were selected. Special attention required in: admission of a patient to the ward, sterilization, verbal communication with the patient, using of intravenous cannulas, needles, syringes, devices for transfusion of infusion liquids, servicing of hospital rooms, first aid in life-threatening situations, using medical devices and equipment. Ten basic causes of the risk of adverse events were identified, among others: lack of trainings, of modern equipment, of staff, failure to comply with procedures, lack of staff supervision, poor quality of ancillary materials, lack of management commitment. Finally MedCARVER+Shock method and Pareto analysis usability has been confirmed but it appeared that it is time-consuming and requires support from skilled professionals. Several suggestions have been put forward to improve the utility of MedCARVER+Shock.
Authentic assessment: An instructional tool to enhance students learning

This paper underscores the process of using authentic assessment as a learning tool in a school the context of Pakistan. Data was collected through classroom observations, conducting interviews, analyzing relevant documents and maintaining person reflective diary. Findings indicate desirable changes in the perception as well as practices of teachers and students. Replacement of traditional paper-pencil test with authentic assessment resulted in active participation of teachers and students in teaching and learning process. Study finding also reveal considerable improvement in high order skills of the students. They were actively engaged in planning, collecting information and disseminating it to the community. Use of rubric for assessment was found to be very effective in determining a pathway for both the teachers and the students to look for and get to the desirable results .
The effects of PI3K/Akt/mTOR Signaling Pathway Inhibitors on Immune Evasion Mechanisms of Acute Myeloid Leukemia Cell Line

Purpose: One of the most important immune escape mechanisms of AML is the up-regulation of immune checkpoint ligands. Herein, we have investigated the relationship between the inhibition of these pathways and the expression regulation of the immune checkpoint ligands in AML cells. Methods: HL-60 cell line was treated with different inhibitors including idelalisib as PI3K inhibitor, MK-2206 as Akt inhibitor, and everolimus as mTOR inhibitor either in single or combination therapy. Cell viability and apoptosis were evaluated using MTT and flow cytometry assays, respectively. The relative expression of PD-L1, galectin-9, and CD155 was determined by Real-Time PCR. Results: Our findings demonstrated decreasing in proliferation and increasing in apoptosis of HL60 cells after treatment with idelalisib, MK-2206, and everolimus. As expected, combined treatment showed more growth inhibition when compared to single treatment. Interestingly, our results demonstrated that the expression of PD-L1 and Gal-9 but not MK-2206, was decreased after treatment with idelalisib and everolimus. Regarding CD155, the expression of this molecule was downregulated after treatment with everolimus, but not idelalisib and MK-2206. However, combined treatment of HL-60 cells with two or three inhibitors decreased the expression levels of PD-L1, Gal-9 and CD155 checkpoint ligands. Conclusion: We showed that PI3K/Akt/mTOR pathway inhibitors not only serve as cytotoxic drugs, but also regulate the expression of immune checkpoint ligands and interfere with the immune evasion mechanisms of AML leukemic cells. Combinational therapy approaches to block these pathways might be a promising and novel therapeutic strategy for AML patients via interfering in immune escape mechanisms.
Charles A. Dice Center for Research in Financial Economics Which Factors

Many recently proposed, seemingly different factor models are closely related. In spanning tests, the q-factor model largely subsumes the Fama-French (2015, 2018) 5and 6-factor models, and the q-model captures the Stambaugh-Yuan (2017) model. The Stambaugh-Yuan factors are sensitive to their construction, and once replicated via the standard approach, are close to the q-factors, with correlations of 0.8 and 0.84. Finally, it seems difficult to motivate the Fama-French 5-factor model from valuation theory, which predicts a positive relation between the expected investment and the expected return. Fisher College of Business, The Ohio State University, 820 Fisher Hall, 2100 Neil Avenue, Columbus OH 43210; and China Academy of Financial Research (CAFR). Tel: (614) 292-0552. E-mail: hou.28@osu.edu. E. J. Ourso College of Business, Louisiana State University, 2931 Business Education Complex, Baton Rouge, LA 70803. Tel: (225) 578-0648. E-mail: haitaomo@lsu.edu. Lindner College of Business, University of Cincinnati, 405 Lindner Hall, Cincinnati, OH 45221. Tel: (513) 556-7078. E-mail: xuecx@ucmail.uc. edu. Fisher College of Business, The Ohio State University, 760A Fisher Hall, 2100 Neil Avenue, Columbus OH 43210; and National Bureau of Economic Research (NBER). Tel: (614) 292-8644. E-mail: zhanglu@fisher.osu.edu. This paper supersedes our previous work circulated under the titles “A Comparison of New Factor Models” and “Motivating Factors. ” For helpful comments, we thank our discussants Ilan Cooper, Raife Giovinazzo, Serhiy Kozak, Kai Li, Scott Murray, David Ng, Christian Opp, Jay Shanken, Timothy Simin, and Zhenyu Wang, as well as Jonathan Berk, Michael Brennan, David Chapman, Andrei Goncalves, Don Keim, Jim Kolari, Dongxu Li, Jim Poterba, Berk Sensoy, Rob Stambaugh, René Stulz, Sheridan Titman, Michael Weisbach, Tong Yao, and other seminar participants at Baruch College, Cheung Kong Graduate School of Business, Georgia Institute of Technology, Guanghua School of Management at Peking University, PBC School of Finance at Tsinghua University, Shanghai University of Finance and Economics, Seoul National University, Texas A&M University, The Ohio State University, University of Iowa, University of Miami, University of Missouri, and University of Southern California, as well as the 2015 Arizona State University Sonoran Winter Finance Conference, the 2015 Chicago Quantitative Alliance Annual Academic Competition, the 2015 Financial Intermediation Research Society Conference, the 2015 Florida State University SunTrust Beach Conference, the 2015 Rodney L. White Center for Financial Research Conference on Financial Decisions and Asset Market at Wharton, the 2015 Society for Financial Studies Finance Cavalcade, the 2015 University of British Columbia Summer Finance Conference, the 2016 HKUST Finance Symposium, the 27th Annual Conference on Financial Economics and Accounting, and the 7th McGill Global Asset Management Conference. All remaining errors are our own.
Unholy alliance? Assessing the links between organised criminals and terrorists in Southern Africa

Following the events of 11 September 2001, the international community has increasingly examined the possible linkages between terrorist groupings and organised criminals. The structural, economic, social and political weaknesses in the Southern African subregion, combined with well-organised and firmly entrenched criminal networks, would, on the face of it, suggest that linkages between organised crime and terrorism are plausible. However, none of the cases examined in this paper could establish a clear linkage between the two phenomena. They show, instead, that terrorists may have interacted with organised criminals in straightforward business deals, on an adhoc basis. Entering into a close and more permanent arrangement with terrorists would not feature on the agendas of organised criminal groups unless there was an immediate financial gain. Ultimately, ongoing collaboration would heighten the risk of detection for both parties. Furthermore, there is little political or ideological common ground between terrorists and criminals to sustain such linkages.
What determine firms’ capital structure in China?

Purpose - – The purpose of this paper is to investigate the determinants of capital structure using a cross-section sample of 1,481 non-financial firms listed on the Chinese stock exchanges in 2011. Design/methodology/approach - – Employing four leverage measures (total leverage and long-term leverage in terms of both book value and market value, respectively) this study examines the effects of factors with proven influences on capital structure in literature, along with industry effect and ownership effect. Findings - – The authors find that large firms favour debt financing while profitable firms rely more on internal capital accumulation. Intangibility and business risk increase the level of debt financing but tax has little impact on capital structure. The authors also observe strong industrial effect and ownership effect. Real estate firms borrow considerably more and firms from utility and manufacturing industries use more long-term debt despite compared with commercial firms. On the other hand, firms with state ownership tend to borrow more, while firms with foreign ownership choose more equity financing. Research limitations/implications - – The study uses cross-section data to avoid any potential time effects, which allows the authors to focus on their main research question – to identify the determinants of capital structure for Chinese firms. Future research may gain more insights using panel data and considering other factors such as crisis and financial reforms. Practical implications - – These results may provide important implications to investors in making investment decision and to firms in making financing decisions. Originality/value - – This paper uses by far the largest and latest cross-section sample from the Chinese stock markets, offering a more complete picture of the financing behaviours in the Chinese firms, with known characters and the impact of ownerships.
Influence of structural physiognomies of pawpaw fiber–glass fiber hybrid–based green composites on mechanical properties and biodegradation potential of epoxy composites

The demand for durable and sustainable eco-friendly materials in recent times has caused many researchers to consider the use of plant fibers in composite development. In this research, the suitability of treated pawpaw fiber as a substitute for glass fiber was considered. The pawpaw fiber was extracted from the plant stem by dew retting and treated before been incorporated into the epoxy matrix. Two distinct fiber structures in linear and network forms were identified, separated, and used for the development of the composites. The composites were produced by incorporating a fixed amount of pawpaw fiber with a varied amount of glass fiber within 3–15 wt% in epoxy-based polymer matrix after which mechanical and biodegradation tests were carried out on the developed samples. Fractured surface morphology was also observed using a scanning electron microscope. The results revealed that the fiber structures influence the properties of the material. While mechanical properties were mostly enhanced by treated linear structure pawpaw fiber, biodegradation was highly promoted by treated network structure pawpaw fiber. Tensile (except for strain), hardness, and flexural properties were enhanced by the linear-structured treated pawpaw fiber, while biodegradability, impact, and tensile strain were improved by the network-structured treated pawpaw fiber compared to the control sample.
The Effect of Good Corporate Governance, Leverage and Company Profile on Risk Disclosure

This research aims to examine the effect of Good Corporate Governance, leverage, and company profile on risk disclosure. Risk disclosure is the disclosure of information relating to risks presented in a company's financial statements in accordance with the type of risk studied. Good Corporate Governance in this research consist of commissioners and directors 'meetings, attendance of commissioners and directors' meetings and company size. This research is quantitative research on state-owned companies listed on the Indonesia Stock Exchange in 2014-2018 using the entire population in the study consisting of 20 populations and 100 observations. Multiple regression analysis is performed to analyze the data. The results showed the presence of board of commissioners and directors’ meetings, company size and company profile influence on risk disclosure. While meeting frequency of board commissioners and directors, leverage have no effect on risk disclosure.