Miracle-dz/UniFAR-FTUs huggingface dataset:
Plants and their environments proceedings of the first biennial scientific conference on the greater Yellowstone ecosystem

Knowledge of the factors that affect plant establishment processes in alpine ecosystems is essential for restoring disturbed areas, conserving rare or endangered species, and understanding changes in species distributions caused by global change. This paper reviews available literature on plant establishment in tundra environments and synthesizes eight years of research on plant establishment processes in an alpine ecosystem on the Beartooth Plateau, Montana. In alpine ecosystems, constraints on the production of viable seeds and the acquisition of favorable microsites may be at least as important as the ability of seedlings to survive different environmental conditions. High variability exists in the viable seed rain both among years and within species. Individual species vary in seed longevity and seed germination characteristics, and the numbers of seeds that carry over from one year to the next is species specific. Seed entrapment in desirable microsites is highly dependent upon soil surface characteristics. On exposed soils relationships among seed morphological attributes and soil particle size can determine both the horizontal and vertical movement of seeds. The physical and chemical properties of disturbed soils determine nutrient and temperature regimes and thus have a substantial effect on seedling growth and survival. In our studies species differed in growth and survival, but survival of most species exceeded 50 percent after five years on ^The use of trade or firm names in this paper is for reader information and does not imply endorsement by the U.S. Department of Agriculture of any product or service.
Geothermometry, geobarometry and the Al2SiO5 triple point at Mt. Moosilauke, New Hampshire

The distribution of aluminum silicate minerals in pelitic schists constrains pressure and temperature conditions during the Acadian Orogeny to have been approximately those of the Al 2 SiO 5 invariant point, thus providing an excellent opportunity to evaluate the internal consistency of a variety of published geothermometers and geobarometers with the Al 2 SiO 5 invariant point of Holdaway (1971). Four fluid-independent equilibria yield P-T estimates consistent with Holdaway (1971). Two fluid-dependent equilibria yield internally consistent but unrealistically high temperatures. Our data are consistent with the conclusions that: (1) only pyrope-grossular mixing in the quaternary garnet system is significantly non-ideal; and (2) the activity coefficient for the anorthite component in plagioclase is approximately 2 at triple point P-T conditions. --Modified journal abstract.
Forms of Migrant Participation in Traditional Village Life in Bali

This research was conducted with the aim of analyzing the forms of migrant participation based on their status in traditional villages in carrying out awig-awig, as well as analyzing the forms of migrant participation based on their typology in carrying out awig-awig in traditional villages. To achieve this aim, this research used a descriptive design with the research subjects being migrants living in the Kampial Traditional Village, Bali. Migrants as subjects and research populations are very large in number, so a number of samples will be taken using accidental sampling techniques in accordance with the limits created. Data collection was carried out by interviews and documentation. The data was then analyzed qualitatively. The research results show that migrant activities related to awig-awig have been carried out by migrants, especially those with krama tamiu status, with a potentially permanent typology. Apart from the status and typology above, several activities in accordance with existing awig-awig are not yet fully carried out by migrants. Special attention is needed, especially to migrants with tamiu status and circular typology (potentially permanent or circular) to be more involved in non-sensitive traditional village activities (pawongan and palemahan).
Modulation of attention to pain by goal-directed action: a somatosensory evoked potentials approach

Background Attentional processes are modulated by current goal pursuit. While pursuing salient cognitive goals, individuals prioritize goal-related information and suppress goal-irrelevant ones. This occurs in the context of pain too, where nonpain cognitive goal pursuit was found to have inhibitory effects on pain-related attention. Crucially, how pursuing nonpain motor goals affects pain-related somatosensory attention is still unknown. The aim of this study was to investigate whether nonpain motor goal pursuit would attenuate pain-related somatosensory attention. Methods Healthy volunteers (N = 45) performed a robotic arm conditioning task where movements were paired with conflicting (pain and reward), threatening (only pain) or neutral (no pain and no reward) outcomes. To increase the motivational value of pursuing the nonpain motor goal, in the conflicting condition participants could receive a reward for a good motor performance. To examine somatosensory attention during movement, somatosensory evoked potentials (SEPs; N120 and P200) were obtained in response to innocuous tactile stimuli administered on a pain-relevant or pain-irrelevant body location. We expected that the threat of pain would enhance somatosensory attention. Furthermore, we expected that the possibility of getting a reward would inhibit this effect, due to pain-reward interactions. Results Against our predictions, the amplitude of the N120 did not differ across movement types and locations. Furthermore, the P200 component showed significantly larger SEPs for conflicting and threat movements compared to neutral, suggesting that the threat of pain increased somatosensory attention. However, this effect was not modulated by nonpain motor goal pursuit, as reflected by the lack of modulation of the N120 and P200 in the conflicting condition as compared to the threat condition. This study corroborates the idea that pain-related somatosensory attention is enhanced by threat of pain, even when participants were motivated to move to obtain a reward.
Risankizumab for the Treatment of the Patients with Moderate to Severe Plaque Psoriasis During a 24-Week Period: Real-Life Experience

Introduction Several authors have reported their experiences in real-world clinical practice, confirming the therapeutic efficacy of risankizumab in plaque psoriasis. We aimed to reflect our experience with risankizumab treatment in patients with psoriasis. Materials and Methods Patients who presented to the dermatology outpatient clinics of two tertiary care centers between November 2021 and August 2022, diagnosed with psoriasis and treated with risankizumab, constituted the target population. Data including gender, age, weight, type of psoriasis, affected body sites, disease duration, previous treatments, duration of risankizumab treatment, psoriasis area and severity index scores, comorbidities, the reasons for drug discontinuation, adverse effects, and the patients’ naïve or non-naïve status were obtained from electronic patient folders. Results Overall, 120 cases were included. While 73 (60.8%) cases were male, 47 (39.2%) were female. Eighty-six (68.3%) of all cases were biologic non-naive. A total of 49 patients (40.8%) had comorbidities. No significant correlations existed between biologic-naïve or non-naïve status, comorbidity status, and the PASI 75-90-100 responses. Conclusion Risankizumab is an effective treatment option for both biologic naive or non-naive patients with or without comorbidities. However, long-term studies, including more extensive patient series, are needed to validate its efficacy and safety in real-life clinical settings.
Efficacy Testing of Anthelmintics against Field strains of Trichostrongyles in Cattle Farms of the Periurban Zone of Ngaoundere in Cameroon

A survey to investigate the prevalence of anthelmintic resistance (AR) in gastrointestinal nematodes on cattle farms was conducted from October 2014 to May 2015 with the common brands of anthelmintics sold in rural veterinary drug shops in Adamawa Region using Faecal Egg Count Reduction Tests (FECRT). 172 animals, homogeneous regarding weight and age were retained. Animals with egg per gram (EPG)≥50 were randomly assigned to control and treatment groups. 10 to 20 animals where possible were randomly selected per farm. Animals in the treatment groups were either given subcutaneously: ivermectin1(1ml/50kg body weight), or ivermectin 2 (0.2 mg/kg bodyweight), or orally levamisole (½ Bolus /40kg equivalent 7.5mg/kg), albendazole (1 bolus/80 kg), oxfendazole or a combination of half orally levamisole and half subcutaneously ivermectin1. Two FECRT methods (Coles et al.,1992): arithmetic mean and Presidente (1985): geometric mean)were used. A reduction of the faecal egg count below 95% plus a lower confidence limit below 90% strongly indicates the presence of AR while the presence of only one of the two parameters suggests an onset of AR. FECRT results using Coles et al. (1992) showed that responses with Ivermectin1 were 64, 81, and 81% in 3 different farms. Those with Ivermectin 2 were 85%, Albendazole 100%, Levamisole 72, 74, 88% in 3 different farms, oxfendazole 85% and ivermectin\Levamisole combination 100%. Using the calculation of Presidente (1985), all the % FECRT were above 90%, except for ivermectin1 79%. Cooperia spp was the predominant species on Day0 and Day14, followed by H. contortus in samples on 4 farms post-treatment. Suspected AR was observed with all anthelmintics, except with albendazole and the combination levamisole\ivermectin.
“I Was Very Shocked, I Wanted It to Be Over”: A Qualitative Exploration of Suicidal Ideation and Attempts among Women Living with HIV in Indonesia

HIV diagnosis and poor HIV management have various detrimental impacts on the lives of people living with HIV (PLHIV). As a part of a large qualitative study investigating HIV risk factors and impacts, of which the topic of suicide is not a focus, this paper describes the factors contributing to suicidal ideation and attempts that arose naturally in the stories of women living with HIV (WLHIV; n = 52) in Yogyakarta and Belu districts, Indonesia. The participants were recruited using the snowball sampling technique. Guided by a qualitative data analysis framework, the data were thematically analysed. The findings were grouped into four main themes: (i) the women experienced immense psychological challenges due to the infection, spousal transmission, fear of mother-to-child transmission, and losing a child due to AIDS, which triggered suicidal ideation and attempts; (ii) the lack of awareness of HIV management strategies resulted in them feeling trapped and overwhelmed, and the associated negative thoughts and the anticipation and experience of HIV stigma influenced their thoughts of suicide; (iii) the lack of social support from family and friends during the early stages of HIV diagnosis, compounded with pre-existing financial difficulties, lack of income, unemployment, and feeling overburdened, also triggered the women’s thoughts of suicide; and (iv) family breakdown following HIV diagnosis, concern about future relationships, and fear of being rejected or abandoned by their partner were also influencing factors for suicidal ideation and attempts among the women. The findings indicate the need for a nuanced approach to counselling within HIV care interventions for couples to support the acceptance of each other’s HIV status whilst maintaining psychological wellbeing. Additionally, the findings indicate the importance of HIV education and awareness among community members for the de-stigmatisation of HIV and to increase the acceptance of PLHIV by their families and communities.
Sentinel Lymph Node Staging in Early-Stage Cervical Cancer: A Comprehensive Review

Cervical cancer (CC) continues to be a significant global public health concern, even with preventive measures in place. In women with early-stage CC, the status of lymph nodes is of paramount importance, not only for the final prognosis but also for determining the best therapeutic strategy. According to main international guidelines, pelvic full lymphadenectomy (PLND) is recommended for lymph node staging. However, in these early stages of CC, sentinel lymph node biopsy (SLNB) has emerged as a precise technique for evaluating lymph node involvement, improving its morbidity profile. We performed a literature review through PubMed articles about progress on the application of SLNB in women with early-stage CC focusing on the comparison with PET/CT and PLND in terms of oncological outcomes and diagnostic accuracy. While the superiority of SLNB is clear compared to radiologic modalities, it demonstrates no clear oncologic inferiority over PLND, given the higher detection rate of positive lymph nodes and predominance of no lymph node recurrences. However, due to a lack of prospective evidence, particularly concerning long-term oncological safety, SLNB is not the current gold standard. With careful patient selection and adherence to straightforward protocols, a low false-negative rate can be ensured. The aim of the ongoing prospective trials is to address these issues.
Upper Midwest farmer perceptions: Too much uncertainty about impacts of climate change to justify changing current agricultural practices

To be uncertain is to be unsure or have doubt. Results from a random sample survey show the majority (89.5%) of farmers in the Upper Midwest perceived there was too much uncertainty about the impacts of climate to justify changing their agricultural practices and strategies, despite scientific evidence regarding the causes and potential consequences of climate change. This study uses random sample survey data (n = 4,778) and in-depth interviews (n = 159) of Upper Midwest farmers to better understand factors that underlie their uncertainty and reluctance to take adaptive action. Results reveal that farmers' uncertainty about projected climate change impacts on their production systems is influenced by their beliefs about climate change, experiences with drought, concern about heat stress on crops, and agricultural information networks. Findings suggest a combination of insufficient information and normative influences on climate beliefs are influencing farmer uncertainty. In cases where uncertainty is caused by insufficient information, improved farmer access to and use of historical crop and local climate records, as well as decision support tools that simulate different climate scenarios and their impacts on production, could improve estimates of future risks. However, more information may be insufficient to address claims of uncertainty when differing political and cultural norms contest the parameters of climate change. This suggests that scientific knowledge must be linked to social values and beliefs and trusted agricultural networks for widespread adaptive management to a changing climate to occur.
Data report: distribution and sources of tetraether lipids in Oligocene deposits from the western North Atlantic, IODP Sites U1406 and U1411

We have analyzed the distribution of glycerol dialkyl glycerol tetraether lipids (GDGTs) in the Oligocene succession recovered by Integrated Ocean Drilling Program Expedition 342. The two studied sites, U1406 and U1411, penetrate a highly expanded section of the upper Eocene–Oligocene–lower Miocene succession. The branched isoprenoid tetraether (BIT) index varies between 0.2 and 0.85, implying that there was a moderate to high influx of soil organic matter to both sites. Furthermore, during the late Oligocene (Chattian) the influx was lower than during the early Oligocene (Rupelian). The methane index (MI) and %GDGT-0 index values suggest that methanotrophic Euryarchaeota and methanogenic archaea are not the main source of GDGTs, but rather marine Thaumarchaeota.
Application of Digital Comic Media to Improve Student Understanding of Pancasila and Citizenship Education Subjects

This study aims to determine the application of digital comic media in increasing students' understanding of Pancasila and Citizenship Education subjects. This study uses a quantitative approach to quasi-experimental design, in the form of a nonequivalent control group design. The sampling technique was purposive sampling in class XI MIPA at SMAN 16 Garut Regency. Data collection techniques through tests in the form of multiple choices. Data analysis techniques through the N-Gain test. The research results show that; The main function of learning media is digital comic media as a teaching aid that is arranged and created by the teacher to influence the climate, conditions and learning environment, making comic media with attention, the storyline presented is interesting, using an attractive appearance and the language used is good, Presentation of simple material, Results of the N-Gain Test treatment (treatment) using digital comic learning media in learning Pancasila and Citizenship Education, student learning outcomes have higher effectiveness than conventional learning. The teacher's obstacles in implementing digital comic media, namely, first; a good editing process, second; comic media that is made must be in accordance with the theme or material that will be conveyed to students, third; It takes quite a long preparation and application time.
Pediatric Ependymoma Treatment: where are we today?

Background: Ependymomas are the second most common pediatric central nervous system tumors with origin from glial cells, with a high incidence in the 0-4 age group. They are histologically classified into grades I, II and III by the World Health Organization (WHO) and, by associating this classification with other characteristics of the tumor and the patient the best option of treatment is constructed, individualizing each situation. Objective: This study aims to conduct a literature review of current treatments for pediatric ependymomas. Methods: The review was made searching the National Library of Medicine (Pubmed), Scientific Electronic Library Online (Scielo), and Latin American and Caribbean Literature in Health Sciences (Lilacs) databases with the keywords “tratamento ependymoma pediátrico” and “ependymoma treatment pediatric”, including texts in Portuguese and English, from 2018 to 2022, regardless of gender and age group of the child. Abstracts, editorials, duplicate articles, chapters, non free access articles and those that lack treatment innovations were not included. Results: At the end, 17 articles were selected for the review, which concluded that the main treatment remains the total resection, and when this is not possible, surgical reapproach and/or radiotherapy, which is essential in subtotal exeresis, metastases and inoperable cases. Finally, there is a need for studies with a larger cohort, evaluating the different treatments and their effectiveness in different cases.
Gender differences in vitiligo: psychological symptoms and quality of life assessment description

Objective Assuming that the difference exist in the manifestation of psychological suffering among genders, the purpose of this review is to summarize the current knowledge on gender differences in vitiligo quality of life and psychological assessment. Methods We searched in PubMed, Scopus, and Web of Science databases for original articles in English language. Results were screened according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA checklist). Results The study yielded 107 results; 12 articles have been evaluated as eligible. Each eligible study has been screened and analyzed. The study’s qualitative evaluation revealed that 8 papers were classifiable as satisfactory, 4 were classifiable as unsatisfactory. The agreement between the coders was high (% agreement = 84.6%; Cohen’s kappa = 0.79). All considered researches (100%) were cross-sectional studies, based on self-report questionnaires. From our analysis, women with vitiligo had a higher risk to experience lower quality of life, and worse mental health in a wide range of psychopathology symptoms than men. A wide heterogeneity of tools is used to investigate the quality of life and psychological symptoms among these patients. Conclusion Unfortunately, there are few explanatory models proposed in the literature to rationalize these findings. It will be important to investigate in further researches the specific influence of known risk factors for psychopathology in this population to better explore these phenomena.
Prediction of Innovation Capability: the Role of Mediation in the Relationship between Digital Transformation and Competitiveness with the PLS-SEM Model

The importance of happiness management This study explores the mediating role of innovation capabilities (IC) on the relationship of digital transformation (DT) and competitiveness (CP), by proposing model construction. Four research questions and four hypotheses were posed. The survey method was carried out by distributing research instruments to 98 respondents, the collected data was used to analyze the relationship between digital transformation, innovation ability and competitiveness, also used to test hypotheses. Evaluation of predictions through structural equation models with partial least squares-structural equation modeling (PLS-SEM). Research findings show that digital transformation directly has a significant positive effect on competitiveness. Digital transformation directly has a significant positive effect on competitiveness. Digital transformation has a significant positive effect on innovation capabilities. The innovation capability has a significant positive influence on competitiveness. Innovation capabilities are proven to have a mediating effect on the influence of digital transformation on competitiveness.
Comparative miRNA expression profile analysis of porcine ovarian follicles: new insights into the initiation mechanism of follicular atresia

Follicular atresia occurs in every stage of ovarian development, which is relevant to female fertility. In the past decade, increasing studies have confirmed that miRNAs, a class of short non-coding RNAs, play an important role in follicular atresia by post-transcription regulation of their target genes. However, the function of miRNAs on follicular atresia initiation is unknown. In the present study, high-throughput small RNA sequencing was performed to analyze differential miRNA expression profiles between healthy (HF) follicles and early atretic (EAF) follicles. A total of 237 conserved miRNA were detected, and the miR-143 is the highest expressed in follicles. Meanwhile, we also found wide sequence variations (isomiRs) in porcine ovarian miRNA, including in 5′un-translation region, core seed sequences and 3′untranslation region. Furthermore, we identified 22 differentially expressed miRNAs in EAF groups compared to HF group, of which 3 miRNAs were upregulated, as well as 19 miRNAs were downregulated, and then the RT-PCR was performed to validate these profiles. The target genes of these differentially expressed miRNAs were predicted by using miRwalk, miRDB, and Targetscan database, respectively. Moreover, the gene ontology and KEGG pathway enrichment established that the regulating functions and signaling pathways of these miRNAs contribute to follicular atresia initiation and cell fate. In conclusion, this study provides new insights into the changes of miRNAs in early atretic follicles to demonstrate their molecular regulation in ovarian follicular atretic initiation.