Miracle-dz/UniFAR-FTUs huggingface dataset:
Continual Vision-Language Representation Learning with Off-Diagonal Information

Large-scale multi-modal contrastive learning frameworks like CLIP typically require a large amount of image-text samples for training. However, these samples are always collected continuously in real scenarios. This paper discusses the feasibility of continual CLIP training using streaming data. Unlike continual learning based on self-supervised learning methods for pure images, which is empirically robust against catastrophic forgetting, CLIP's performance degeneration in the continual setting is significant and non-neglectable. By analyzing the changes in the model's representation space during continual CLIP training from a spatial geometry perspective, we explore and summarize these spatial variations as Spatial Disorder (SD), which can be divided into Intra-modal Rotation and Inter-modal Deviation. Moreover, we empirically and theoretically demonstrate how SD leads to a performance decline for CLIP on cross-modal retrieval tasks. To alleviate SD, we propose a new continual vision-language representation learning framework Mod-X: Maintain off-diagonal information-matriX. By selectively aligning the off-diagonal information distribution of contrastive matrices, the Mod-X improves the capability of the multi-modal model by maintaining the multi-modal representation space alignment on the old data domain during continuously fitting the new training data domain. Experiments on commonly used datasets with different scales and scopes have demonstrated the effectiveness of our method.
MEGABYTE: Predicting Million-byte Sequences with Multiscale Transformers

Autoregressive transformers are spectacular models for short sequences but scale poorly to long sequences such as high-resolution images, podcasts, code, or books. We proposed Megabyte, a multi-scale decoder architecture that enables end-to-end differentiable modeling of sequences of over one million bytes. Megabyte segments sequences into patches and uses a local submodel within patches and a global model between patches. This enables sub-quadratic self-attention, much larger feedforward layers for the same compute, and improved parallelism during decoding -- unlocking better performance at reduced cost for both training and generation. Extensive experiments show that Megabyte allows byte-level models to perform competitively with subword models on long context language modeling, achieve state-of-the-art density estimation on ImageNet, and model audio from raw files. Together, these results establish the viability of tokenization-free autoregressive sequence modeling at scale.
Amenability problem for Thompson's group $F$: state of the art

This is a survey of our recent results on the amenability problem for Thompson's group $F$. They mostly concern esimating the density of finite subgraphs in Cayley graphs of $F$ for various systems of generators, and also equations in the group ring of $F$. We also discuss possible approaches to solve the problem in both directions.
Dyadic partition-based training schemes for TV/TGV denoising

Due to their ability to handle discontinuous images while having a well-understood behavior, regularizations with total variation (TV) and total generalized variation (TGV) are some of the best-known methods in image denoising. However, like other variational models including a fidelity term, they crucially depend on the choice of their tuning parameters. A remedy is to choose these automatically through multilevel approaches, for example by optimizing performance on noisy/clean image pairs. In this work, we consider such methods with space-dependent parameters which are piecewise constant on dyadic grids, with the grid itself being part of the minimization. We prove existence of minimizers for fixed discontinuous parameters under mild assumptions on the data, which lead to existence of finite optimal partitions. We further establish that these assumptions are equivalent to the commonly used box constraints on the parameters. On the numerical side, we consider a simple subdivision scheme for optimal partitions built on top of any other bilevel optimization method for scalar parameters, and demonstrate its improved performance on some representative test images when compared with constant optimized parameters.
Robustness of Bayesian ordinal response model against outliers via divergence approach

Ordinal response model is a popular and commonly used regression for ordered categorical data in a wide range of fields such as medicine and social sciences. However, it is empirically known that the existence of ``outliers'', combinations of the ordered categorical response and covariates that are heterogeneous compared to other pairs, makes the inference with the ordinal response model unreliable. In this article, we prove that the posterior distribution in the ordinal response model does not satisfy the posterior robustness with any link functions, i.e., the posterior cannot ignore the influence of large outliers. Furthermore, to achieve robust Bayesian inference in the ordinal response model, this article defines general posteriors in the ordinal response model with two robust divergences (the density-power and $\gamma$-divergences) based on the framework of the general posterior inference. We also provide an algorithm for generating posterior samples from the proposed posteriors. The robustness of the proposed methods against outliers is clarified from the posterior robustness and the index of robustness based on the Fisher-Rao metric. Through numerical experiments on artificial data and two real datasets, we show that the proposed methods perform better than the ordinary bayesian methods with and without outliers in the data for various link functions.
The use of patient‐reported outcome measures by healthcare professionals in specialized asthma management centers in French‐speaking Belgium: A mixed‐methods study

Abstract Introduction Recently, the literature has promoted the use of patient‐reported outcome measures (PROMs) in clinical practice as a means to foster patient engagement. However, conditions necessary to support the use of PROMs to encourage asthma patient engagement are not clearly defined. Therefore, we sought (1) to explore the current and ideal use of PROMs by healthcare professionals (HP) in specialized asthma management centers in French‐speaking Belgium and (2) to understand under which conditions the use of PROMs contributes to patient engagement. Methods We undertook a mixed‐methods study with both anonymous online survey and in‐person qualitative semi‐structured interviews conducted with HPs to understand their perspectives on the routine use of PROMs. HPs were recruited from 16 asthma centers (French‐speaking Belgium) identified via the Belgian Respiratory Society. Results Of the 170 HPs identified from the 16 participating centers, 51 (30%) responded to the survey (n = 51) and 11 completed semi‐structured interviews. 53% (27/51) of the surveyed HPs reported using PROMs primarily for asthma monitoring and clinical research while all reported that PROMs should primarily be used in practice to facilitate communication with the patient and to address neglected aspects of the care relationship such as the psychosocial aspects of the disease. The qualitative interviews revealed avenues for moving from a medical‐centered and utilitarian use of PROMs to a use serving patient engagement. This would require HPs to go beyond their current representation of PROMs, to use instruments offering a more holistic image of the patient, to incorporate PROMs into a digital tool and to integrate PROMs in a patient education process. Conclusion The main findings of this study suggest relevant avenues for using PROMs in ways that support patient engagement.
Influence of latrine coverage and usage on diarrhoea incidence among children under 5 living in slum areas of Douala 5th sub-division, Cameroon

Introduction lack of adequate sanitation facilities remain a major concern in developing countries. While around 41% of Cameroonians lack access to improved sanitation facilities, the 2011 National Survey revealed a diarrhoea incidence rate of 21% in children under five years, two weeks before interview. This study aimed at evaluating the influence of latrine coverage and usage on diarrhoeic disease outcomes among children under 5. Methods a cross-sectional study was carried out in March 2016 in pre-selected slums areas of Douala 5th district. A structured questionnaire was used to collect data from one consenting adult per household. Data analysis was carried out using Epi Info version 7.1. 4.0. Pearson’s chi-square and Fisher exact test were used to estimate the influence of latrine coverage on the incidence of diarrhoea. Statistical significance was set at p < 0.05. Results of the 384 households enrolled, 69.01% had latrine facilities, while 30.99% shared latrines with neighbouring households. Sixty point sixteen percent (60.16%) (231/384) of all households used pit latrines. Although consistent use of latrines by all adults was reported, 20.05% of children under 5 practiced open-air defecation. The incidence of diarrhoea among children under 5 years 2 weeks before interview was 29.25%, of which 26.35% were bloody stools. Diarrhoea outcome was significantly associated with use of pit latrines (p < 0.01); lack of cover on latrines hole (p < 0.0001) and proximity of latrines to household (p=0.01). Conclusion poor faecal waste management and lack of improved sanitation facilities contribute significantly to diarrhoeal episodes among children under 5. A structured strategy to improve community-based sanitation considering urban planning and sanitation campaigns would promote safer environment and reduce outcome of water-borne and diarrhoeic diseases.
Recent Developments in Gauge Theories

Almost all theories of fundamental interactions are nowadays based on the gauge concept. Starting with the historical example of quantum electrodynamics, we have been led to the successful unified gauge theory of weak and electromagnetic interactions, and finally to a non abelian gauge theory of strong interactions with the notion of permanently confined quarks. The. early theoretical work on gauge theories was devoted to proofs of renormalizability, investigation of short distance behaviour, the discovery of asymptotic freedom, etc . , aspects which were accessible to tools extrapolated from renormalised perturbation theory. The second phase of the subject is concerned with the problem of quark confinement which necessitates a non-perturbative understanding of gauge theories. This phase has so far been marked by the introduc tion of ideas from geometry, topology and statistical mechanics in particular the theory of phase transitions. The 1979 Cargese Institute on "Recent Developments on Gauge Theories" was devoted to a thorough discussion of these non-perturbative, global aspects of non-abelian gauge theories. In the lectures and seminars reproduced in this volume the reader wilf find detailed reports on most of the important developments of recent times on non perturbative gauge fields by some of the leading experts and innovators in this field. Aside from lectures on gauge fields proper, there were lectures on gauge field concepts in condensed matter physics and lectures by mathematicians on global aspects of the calculus of variations, its relation to geometry and topology, and related topics. "
Guidelines on the classification of foot ulcers in people with diabetes (IWGDF 2023 update).

BACKGROUND This publication represents a scheduled update of the 2019 guidelines of the International Working Group of the Diabetic Foot (IWGDF) addressing the use of systems to classify foot ulcers in people with diabetes in routine clinical practice. The guidelines are based on a systematic review of the available literature that identified 28 classifications addressed in 149 articles and, subsequently, expert opinion using the GRADE methodology. METHODS First, we have developed a list of classification systems considered as being potentially adequate for use in a clinical setting, through the summary of judgements for diagnostic tests, focussing on the usability, accuracy and reliability of each system to predict ulcer-related complications as well as use of resources. Second, we have determined, following group debate and consensus, which of them should be used in specific clinical scenarios. Following this process, in a person with diabetes and a foot ulcer we recommend: (a) for communication among healthcare professionals: to use the SINBAD (Site, Ischaemia, Bacterial infection, Area and Depth) system (first option) or consider using WIfI (Wound, Ischaemia, foot Infection) system (alternative option, when the required equipment and level of expertise is available and it is considered feasible) and in each case the individual variables that compose the systems should be described rather than a total score; (b) for predicting the outcome of an ulcer in a specific individual: no existing system could be recommended; (c) for characterising a person with an infected ulcer: the use of the IDSA/IWGDF classification (first option) or consider using the WIfI system (alternative option, when the required equipment and level of expertise is available and it is considered as feasible); (d) for characterising a person with peripheral artery disease: consider using the WIfI system as a means to stratify healing likelihood and amputation risk; (e) for the audit of outcome(s) of populations: the use of the SINBAD score. CONCLUSIONS For all recommendations made using GRADE, the certainty of evidence was judged, at best, as being low. Nevertheless, based on the rational application of current data this approach allowed the proposal of recommendations, which are likely to have clinical utility.
Sarcopenia in Lung Cancer: A Narrative Review

Abstract It has been over 10 years since the relationship between sarcopenia and lung cancer was first explored. Since then, sarcopenia research has progressed substantially, and the prognostic value of this condition is becoming increasingly apparent. Prior systematic reviews and meta-analyses have established sarcopenia to be negatively associated with disease-free and overall-survival, as well as a major risk factor for post-operative complications. The bulk of the literature has explored sarcopenia in the resectable setting, with less emphasis placed on studies evaluating this condition in advanced disease. In this up-to-date review, an examination of the literature exploring the association between sarcopenia and long-term outcomes in advanced lung cancer is provided. We further explore the association between adverse events of medical therapy and the role of sarcopenia as a predictor of tumor response. Finally, the interventions on sarcopenia and cancer cachexia are reviewed, with an emphasis placed on prospective studies.
Pharmacological augmentation of serotonin reuptake inhibitors in patients with obsessive–compulsive disorder: A network meta‐analysis

The augmentation of serotonin reuptake inhibitors (SRIs) can be achieved by add‐on therapy with different pharmacological agents in obsessive–compulsive disorder (OCD) for a better clinical outcome. This network meta‐analysis (NMA) was conducted to evaluate and compare the effects of available augmentation agents for SRIs in OCD.
Prognostic Value of the Naples Prognostic Score in Patients with Gastrointestinal Cancers: A Meta-Analysis

Abstract This meta-analysis was conducted to systematically evaluate the prognostic role of the Naples prognostic score (NPS) in patients with gastrointestinal (GI) cancers. A comprehensive literature search of several major databases was performed for studies published until October 16, 2022. Hazard ratios (HRs) with 95% confidence intervals (CIs) were extracted and pooled by fixed-effects or random-effects models to analyze the associations between the NPS and overall survival (OS), cancer-specific survival (CSS), and recurrence-free/disease-free survival (RFS/DFS) in GI cancers. Thirteen studies were included in the meta-analysis. Pooled results indicated that a high NPS predicted poor OS (HR = 2.28, 95% CI: 1.90–2.74, p < 0.001), CSS (HR = 2.77, 95% CI: 2.10–3.66, p < 0.001), and RFS/DFS (HR = 2.77, 95% CI: 2.26–3.40, p < 0.001). For OS-related and RFS/DFS-related studies, subgroup analyses showed that a high NPS was significantly associated with poor OS and RFS/DFS irrespective of NPS group, calculation of the NPS, and tumor type. In the study that focused on CSS, subgroup analyses by NPS group and calculation of the NPS revealed similar results. The NPS may represent an effective prognostic indicator in patients with GI cancers.
Parenting Styles and Moral Disengagement in Young Adults: The Mediating Role of Attachment Experiences

Abstract Research on parenting styles and attachment experiences has paid little attention to the dimensions of moral development. It is, therefore, interesting to explore the relationship between parenting styles, internal working models of attachment, and the development of moral skills, in terms of moral disengagement. The study involved 307 young people (aged 19-25 years), and the dimensions examined were: parental styles (measured by the PSDQ: Tagliabue et al., 2014); attachment styles (ECR: Picardi et al., 2002); moral disengagement (MDS: Caprara et al., 2006). Results showed that the authoritative parenting style is negatively correlated with the two measures of attachment styles (anxiety and avoidance) and moral disengagement. The authoritarian and permissive styles are positively correlated with the two measures of attachment styles (anxiety and avoidance) and moral disengagement. Results also revealed a significant indirect effect of the authoritative style (b = −0.433, 95% BCa, CI [−0.882, −0.090]) and authoritarian style (b = −0.661, 95% BCa, CI [.230, 1.21]) on moral disengagement through anxiety. A serial mediation of anxiety and avoidance on the relationship between permissive style and moral disengagement (b = .077, 95% BCa, CI [.0006, .206]) is significant.
High Pressure Elastic Properties of Wurtzite Aluminum Nitrate

Aluminum nitrate is an indisputable material for current optoelectronic technology. Although much scientific effort has been devoted to understanding the ground state elastic properties of aluminum nitrate, little is known about the high pressure elastic behavior of this crucial material. In contrast to previous theoretical methods, we present an application of a shell model interatomic potential for the first time in conjunction with geometry optimization calculations to predict some elastic and relevant properties of wurtzite aluminum nitrate (w-AlN) under pressures up to 50 GPa. The obtained ground state results for the elastic constants, Poisson ratio, elastic wave velocities, and dielectric optical constants agree well with the existing experimental values and better than those of some theoretical data. In addition, the bonding character of w-AlN was found to be ionic for the entire pressure range, whereas elastic isotropy arises for the pressures below 10 GPa. In conclusion, application of shell model potentials to the high pressure properties of w-AlN offers satisfactory results, and these results can be useful for the future experimental and theoretical works on related material under pressure.
On the Lattice of Existence Varieties of Locally Inverse Semigroups

Abstract The mapping which assigns to each existence variety of locally inverse semigroups the class of all pseudosemilattices of idempotents of members of is shown to be a complete, surjective homomorphism from the lattice of existence varieties of locally inverse semigroups onto the lattice of varieties of pseudosemilattices.
Development and Characterization of a AuNP-Genipin-Viscoelastic Collagen Material

Lower back pain is one of the leading causes of disability, affecting 11.9% of the population worldwide and studies have shown that intervertebral disc degeneration is a common cause for chronic lower back pain. We have explored the combination of three components, viscoelastic collagen, genipin, and gold nanoparticles to determine its potential to promote regeneration of the intervertebral disc, specifically for nucleus pulposus regeneration. The goal of this study was to develop, fabricate and characterize different formulations of viscoelastic collagen conjugated with gold nanoparticles and genipin to assess the feasibility as a tissue template. Results demonstrated the successful attachment of gold nanoparticles to the viscoelastic collagen utilizing the genipin crosslinker. For each of the viscoelastic collagen compositions examined, cell biocompatibility was achieved. The results also demonstrated an increase in stiffness of the material with different sizes and concentrations of AuNPs. Results from the TEM and STEM also demonstrated that the viscoelastic collagen that was developed did not display the characteristic D banding pattern of polymerized collagen. The findings from this study could lead to the development of a more efficient and cost-effective treatment for patients with chronic back pain caused by IVD degeneration.
An Experimental Study of Görtler Vortices in Compressible Flow

This study consisted of an experimental investigation of the existence and properties of Gortler vortices in compressible flow. Gortler vortices are counter-rotating pairs of longitudinal vortices that occur as a result of centrifugal instabilities in the boundary layer in flows over curved surfaces with concave curvature. Curved ramp models with a radius of curvature of 25.4 cm or 50.8 cm were mounted in a supersonic blow-down air tunnel with a unit Reynolds number of 4.18-5.96 × 10 7 /m. Mach number was varied from 1.06-2.87. Micro-carbon particulate surface flow visualization was combined with a threshold analysis technique to identify existence and wavelength of Gortler vortices. The results indicate that Gortler vortices do exist in compressible flow, and occur in the regime of flow parameters predicted by compressible stability analyses. It was found that the dimensional Gortler vortex wavelength was between 0.18-0.22 mm and was invariant with Mach number, Gortler number and radius of curvature. This invariance of Gortler vortex wavelength agrees with experimental results from incompressible flow studies.
Simulation and Analysis of Tornado Development and Decay within a Three-Dimensional Supercell Thunderstorm

Abstract A three-dimensional numerical simulation using a two-way interactive nested grid is to study tornado-genesis within a supercell. During a 40-minute period, two tornadoes grow and decay within the storm's mesocyclone. The tornadoes have life spans of approximately 10 minutes. Maximum ground-relative surface wind speeds exceed 60 m s−1 during both tornadoes, and horizontal pressure gradients reach 18 hPa km−1 during the second tornado. Comparison of the simulated storm evolution with Doppler and field observations of supercells and tornadoes shows many similar features. Vertical vorticity in the mesocyclone and the tornado vortex at low levels is initially created by the tilting of the environmental vorticity and baroclinically generated vorticity along the forward gland gust front of the storm. Tornadogenesis is initiated when mesocyclone rotation increase above cloud base. The increased rotation generates lower pressure in the mesocyclone, increasing the upward pressure gradient forces. The upwar.