Miracle-dz/UniFAR-FTUs huggingface dataset:
Gradient boosting machine learning model to predict aflatoxins in Iowa corn

Introduction Aflatoxin (AFL), a secondary metabolite produced from filamentous fungi, contaminates corn, posing significant health and safety hazards for humans and livestock through toxigenic and carcinogenic effects. Corn is widely used as an essential commodity for food, feed, fuel, and export markets; therefore, AFL mitigation is necessary to ensure food and feed safety within the United States (US) and elsewhere in the world. In this case study, an Iowa-centric model was developed to predict AFL contamination using historical corn contamination, meteorological, satellite, and soil property data in the largest corn-producing state in the US. Methods We evaluated the performance of AFL prediction with gradient boosting machine (GBM) learning and feature engineering in Iowa corn for two AFL risk thresholds for high contamination events: 20-ppb and 5-ppb. A 90%–10% training-to-testing ratio was utilized in 2010, 2011, 2012, and 2021 (n = 630), with independent validation using the year 2020 (n = 376). Results The GBM model had an overall accuracy of 96.77% for AFL with a balanced accuracy of 50.00% for a 20-ppb risk threshold, whereas GBM had an overall accuracy of 90.32% with a balanced accuracy of 64.88% for a 5-ppb threshold. The GBM model had a low power to detect high AFL contamination events, resulting in a low sensitivity rate. Analyses for AFL showed satellite-acquired vegetative index during August significantly improved the prediction of corn contamination at the end of the growing season for both risk thresholds. Prediction of high AFL contamination levels was linked to aflatoxin risk indices (ARI) in May. However, ARI in July was an influential factor for the 5-ppb threshold but not for the 20-ppb threshold. Similarly, latitude was an influential factor for the 20-ppb threshold but not the 5-ppb threshold. Furthermore, soil-saturated hydraulic conductivity (Ksat) influenced both risk thresholds. Discussion Developing these AFL prediction models is practical and implementable in commodity grain handling environments to achieve the goal of preventative rather than reactive mitigations. Finding predictors that influence AFL risk annually is an important cost-effective risk tool and, therefore, is a high priority to ensure hazard management and optimal grain utilization to maximize the utility of the nation’s corn crop.
Influences on Prescribed Burning Activity and Costs in the National Forest System

The results of a survey concerning National Forest System prescribed burning activity and costs from 1985 to 1995 are examined. Ninety-five of one hundred and fourteen national forests responded. Acreage burned and costs for conducting burns are reported for four types of prescribed fire: slash reduction; management-ignited fires; prescribed natural fres; and brush, grass and rangeland burns. Rankings of impo&mce are presented for 9 resource enhancement targets, 14 potential barriers to burning, and 12 factors influencing burning costs. Survey responses concerning the presence and impact of Class I and nonattabent air quality areas are discussed. Anticipated burning levels over the next 10 years and burning levels needed to achieve desired management goals on National Forest System lands are also presented.
Alien plant fitness is limited by functional trade‐offs rather than a long‐term increase in competitive effects of native communities

Abstract Alien plants experience novel abiotic conditions and interactions with native communities in the introduced area. Intra‐ and interspecific selection on functional traits in the new environment may lead to increased population growth with time since introduction (residence time). However, selection regimes might differ depending on the invaded habitat. Additionally, in high‐competition habitats, a build‐up of biotic resistance of native species due to accumulation of eco‐evolutionary experience to aliens over time may limit invasion success. We tested if the effect of functional traits and the population dynamics of aliens depends on interspecific competition with native plant communities. We conducted a multi‐species experiment with 40 annual Asteraceae that differ in residence time in Germany. We followed their population growth in monocultures and in interspecific competition with an experienced native community (varying co‐existence times between focals and community). To more robustly test our findings, we used a naïve community that never co‐existed with the focals. We found that high seed mass decreased population growth in monocultures but tended to increase population growth under high interspecific competition. We found no evidence for a build‐up of competition‐mediated biotic resistance by the experienced community over time. Instead, population growth of the focal species was similarly inhibited by the experienced and naïve community. By comparing the effect of experienced and naïve communities on population dynamics over 2 years across a large set of species with a high variation in functional traits and residence time, this study advances the understanding of the long‐term dynamics of plant invasions. In our study system, population growth of alien species was not limited by an increase of competitive effects by native communities (one aspect of biotic resistance) over time. Instead, invasion success of alien plants may be limited because initial spread in low‐competition habitats requires different traits than establishment in high‐competition habitats.
Gender Differences in Facial Emotion Recognition Among Adolescents Depression with Non-Suicidal Self-Injury

Objective Despite the perception that healthy female are superior at emotional identification, it remains unclear whether gender-specific differences exist in adolescent depression and whether such specific differences in emotional recognition are associated with the most salient feature of adolescent depression---non-suicidal self-injury (NSSI). Methods In this study, 1428 adolescents (1136 females and 292 males) with depression and NSSI were examined using the Facial Emotion Recognition Task, Patient Health Questionnaire-9 (PHQ-9), and Functional Assessment of Self-mutilation questionnaire (FASM). This study was grouped by gender. Data were analyzed using the descriptive statistics, independent sample t-test, chi-square test, non-parametric test (Mann–Whitney U-test), Spearman correlation and Multiple linear regression analysis. Results Depressed females reported a significantly greater frequency of self-injurious behaviour and more severe depressive symptoms than males. Face emotion recognition was also significantly more accurate in females and was positively correlated with levels of self-injury and depression, whereas no such correlations were found in males. Among depressed adolescents, face emotion recognition is better in females and is associated with self-injurious behaviour. Conclusion This study found that the greater susceptibility to depression and NSSI among adolescent females may stem in part from superior recognition and sensitivity to the negative emotions of others.
The Stockholm experience

This article details the implementation and running of a trial congestion charging scheme in the city of Stockholm, Sweden in 2006. Objectives of the scheme were to reduce city traffic, improve traffic flow, reduce emissions and improve the city environment. The system was designed and built in just over a year to high standards of punctuality and acceptability. Eighteen automatic control points were set up with technical equipment installed on gantries and at the roadside. Number plates were photographed and identified by optical character recognition. Tax decisions were made on the accumulated vehicle passages in each day. A public information campaign was carried out which eased the transition to the new situation, and extra customer service staff were gradually reduced. Payment by direct debit caused some problems at first. It was found that traffic, queueing time and vehicle emissions decreased in the inner city. Following evaluation, the congestion tax is to be re-introduced in 2007, and more convenient payment methods are being investigated.
Assessment of laparoscopic skills: Comparing the reliability of global rating and entrustability tools Évaluation des compétences en laparoscopie : comparaison de la fiabilité des outils d’évaluation globale et des outils d’évaluation de la confiance

Contexte : Les programmes de résidence structurés autour de la compétence par conception (CPC) dépendent de plus en plus d’outils qui fournissent des évaluations fiables, nécessitent une formation minimale des évaluateurs et mesurent la progression dans les étapes de la CPC. Pour évaluer les compétences peropératoires, les échelles d’évaluation globale et de confiance sont couramment utilisées mais peuvent nécessiter une formation approfondie. Le Continuum des compétences (CC) est un cadre de la CPC qui peut être utilisé comme
Chitin Nanofibrils Enabled Core–Shell Microcapsules of Alginate Hydrogel

An engineered 3D architectural network of the biopolymeric hydrogel can mimic the native cell environment that promotes cell infiltration and growth. Among several bio-fabricated hydrogel structures, core–shell microcapsules inherit the potential of cell encapsulation to ensure the growth and transport of cells and cell metabolites. Herein, a co-axial electrostatic encapsulation strategy is used to create and encapsulate the cells into chitin nanofibrils integrated alginate hydrogel microcapsules. Three parameters that are critical in the electrostatic encapsulation process, hydrogel composition, flow rate, and voltage were optimized. The physicochemical characterization including structure, size, and stability of the core–shell microcapsules was analyzed by scanning electron microscope (SEM), FTIR, and mechanical tests. The cellular responses of the core–shell microcapsules were evaluated through in vitro cell studies by encapsulating NIH/3T3 fibroblast cells. Notably, the bioactive microcapsule showed that the cell viability was found excellent for more than 2 weeks. Thus, the results of this core–shell microcapsule showed a promising approach to creating 3D hydrogel networks suitable for different biomedical applications such as in vitro tissue models for toxicity studies, wound healing, and tissue repair.
A Novel Formulation of Asparaginase Encapsulated into Virus-like Particles of Brome Mosaic Virus: In Vitro and In Vivo Evidence

The interest in plant-derived virus-like particles (pVLPs) for the design of a new generation of nanocarriers is based on their lack of infection for humans, their immunostimulatory properties to fight cancer cells, and their capability to contain and release cargo molecules. Asparaginase (ASNase) is an FDA-approved drug to treat acute lymphoblastic leukemia (LLA); however, it exhibits high immunogenicity which often leads to discontinuation of treatment. In previous work, we encapsulated ASNase into bacteriophage P22-based VLPs through genetic-directed design to form the ASNase-P22 nanobioreactors. In this work, a commercial ASNase was encapsulated into brome mosaic virus-like particles (BMV-VLPs) to form stable ASNase-BMV nanobioreactors. According to our results, we observed that ASNase-BMV nanobioreactors had similar cytotoxicity against MOLT-4 and Reh cells as the commercial drug. In vivo assays showed a higher specific anti-ASNase IgG response in BALB/c mice immunized with ASNase encapsulated into BMV-VLPs compared with those immunized with free ASNase. Nevertheless, we also detected a high and specific IgG response against BMV capsids on both ASNase-filled capsids (ASNase-BMV) and empty BMV capsids. Despite the fact that our in vivo studies showed that the BMV-VLPs stimulate the immune response either empty or with cargo proteins, the specific cytotoxicity against leukemic cells allows us to propose ASNase-BMV as a potential novel formulation for LLA treatment where in vitro and in vivo evidence of functionality is provided.
Public Health Approach in the Elimination and Control of Cervical Cancer: A Review

Public health experts worldwide have emphasized cervical cancer since it is a substantial global health burden primarily affecting women. This article thoroughly reviews the public health approach to eradicating and managing cervical cancer. The public health community seeks to lower the prevalence, morbidity, and mortality linked to this preventable disease by integrating primary prevention by means of vaccination against the human papillomavirus (HPV), secondary prevention using screening and early identification, and tertiary prevention through improved therapy and supportive care. In order to accomplish broad vaccination coverage and ultimately effectively prevent cervical cancer, it remains crucial to address obstacles to vaccine accessibility, reluctance, and fair distribution. Early identification and subsequent treatments depend greatly on cervical cancer screening programs. This study explores several screening methods, such as Papanicolaou (Pap) tests based on cytology and cutting-edge technologies like molecular assays and HPV detection. The detection of precancerous lesions and early-stage malignancies, permitting prompt treatment, has shown significant promise when integrating these technologies into coordinated population-based screening programs. The study also underlines the significance of addressing cervical cancer burden inequities, particularly in resource-constrained areas where access to preventative and curative care is constrained. Innovative and affordable methods for addressing marginalized groups are studied, including community-based outreach programs, mobile health technology, and local healthcare practitioners and community leaders in awareness campaigns. The research also examines improvements in cervical cancer treatment procedures, such as surgery, radiation, chemotherapy, and immunotherapy. It improves therapeutic efficacy and patient survival rates by incorporating various modalities into a multidisciplinary strategy. Highlighted palliative care and psychological support are crucial for patients who have advanced cervical carcinoma.
BeTTer Outcomes Workgroup Health Quality Initiative to optimize bone health for prostate cancer patients in the British Columbia Cancer System.

INTRODUCTION Bone-targeted therapies (BTTs) are integral to the management of bone metastases in metastatic castration-resistant prostate cancer (mCRPC). BTTs vary considerably in referral and drug access pathways and optimal BTT use requires multi-specialty consultation and supervision. Health quality improvement (HQI) has become the predominant framework to improve patient care in multidisciplinary settings. METHODS HQI initiatives on use of BTT in mCRPC were developed and evaluated in five centers of a provincial cancer center network using Plan-Do-Study-Act (PDSA) methodology. Multidisciplinary teams (MDTs) completed a common quality assessment form and an HQI template and then implemented an HQI initiative. Feedback and findings were shared and discussed at regional events. It was subsequently determined whether to adopt, adapt, or abandon initiatives. RESULTS Patterns of unmet needs varied across type of BTT. Gaps in use of radium-223 were mostly referral and education issues that could be directly addressed at the local level by participating clinician teams. Conversely, most supportive BTT gaps were related to coverage and resourcing support. HQI initiatives selected by each site consisted of implementation or expansion of local MDT meetings, referral documents, databases, and improvement charters. The main HQI initiative was completed in four sites and was adapted or adopted in three. Improvements in BTT use were observed in two of three centers with data on HQI process measures. CONCLUSIONS Despite the overall heterogenous structure of the groups and metrics used, this study demonstrated that the PDSA framework provides the needed structure for improvements in BTT use in mCRPC across multiple sites.
GEANT4 Simulation of Photoneutron Spectrum from Medical Linear Accelerator

Photons with energy totaling more than 10 MeV provide efficient treatment for deeply seated tumors but interact with the nuclei of high-Z materials constituting a head of the linac. These interactions result in photoneutrons that deliver an additional out-of-field dose to the patient, which increases the risk of radiation-induced cancer. Monte Carlo simulation is an accurate strategy for estimating the effective photoneutron dose for a patient. In the current study, the possibility of using GEANT4 to calculate the photoneutron spectrum from the medical linac was investigated. The free-in-air photoneutron spectrum from a head of the linac was simulated using the NeutronHP experimental package. Validation of the simulated model was carried out based on a comparison of simulated and measured percentage depth–dose curves from photons in the water phantom. The obtained photoneutron spectrum was compared with the previously measured spectrum at the Varian Thilogy linac. GEANT4 may improve the accuracy of calculations of the effective dose based on photoneutrons. However, the simulated model should be improved and optimized. In the future, this model may constitute a physical basis for the prediction of the risk of radiation-induced cancer at our clinical center.
Radium isotopes in the Orinoco estuary and eastern Caribbean sea. Final technical report

Radium isotopes provide a means of identifying the source of freshened waters in the ocean and determining the time elapsed since these waters were in the estuary. We present evidence that, during April, waters from the Amazon mixing zone pass within 50 km of the mouth of the Orinoco mouth. These Amazon waters are characterized by a lower Ra228/Ra226 activity ratio than are waters from the Orinoco at similar salinities. Within the Caribbean Sea waters of Orinoco origin carry a characteristic radium signature including excess activities of Ra224. This isotope may be used to estimate the time elapsed since the waters were removed from contact with sediments. Current speeds based on Ra224 dating range from 5 to 20 cm/sec during April. Radium isotopes also provide an assessment of sediment mixing in the estuary. During low discharge (April), considerable mixing of older sediment by physical or biological processes or dredging maintained high activities of Ra228 in the estuary and produced the highest Ra228/Ra226 A. R. 's yet measured in any estuary. During the high discharge (Sept.) a large fraction of the Ra228 was derived from desorption from fresh sediment rather than mixing of older sediments. Activities of Ra224 were high in themore » estuary during both high and low discharge, indicating that considerable mixing of recently introduced sediment must occur during each period. The Ra224/Ra228 A. R. 's measured in Sept. imply that the same sediments were being resuspended during high discharge, and that there was little exposure of older sediments which had been stored in the estuary for months to years. « less
Spatio-temporal Distribuution, Abundance and Species Composition of Zooplankton of Woji-okpoka Creek, Port Harcourt, Nigeria

Woji-Okpoka Creek is situated in a strategic location in Port Harcourt, Rivers State, Nigeria and it receives domestic and industrial wastes from the Trans-amadi industrial Layout, main Port Harcourt abattoir and riverine communities. There is little information on the zooplankton of this creek. The study investigated species composition, diversity, abundance and distribution of zooplankton as well as some physico-chemical parameters that affect this organism. Zooplankton and surface water samples were collected monthly from May 2004-April 2006 at low and high tides from ten stations according to APHA methods. These were analysed for temperature, turbidity, transparency, salinity, dissolved oxygen (DO), biological oxygen demand (BOD), pH and nutrients. Zooplankton was identified microscopically. Species diversity was calculated using standard indices. Data was analysed using analysis of variance, Duncan multiple range and descriptive statistics. Zooplankton demonstrated significant temporal variation (P＜0.05). A total of 85 species dominated by copepods (43.4%) were identified. Diversity indices for copepods were: 1.0±0.03 (Margalef) and 0.5±0.02 (Shannon). Water temperature 28.6±0.06℃, turbidity 3.6±0.32 NTU and transparency 0.7±0.01m showed significant temporal variations (P＜0.05). Water chemical parameters were: salinity, 14.4±4.67‰; DO, 5.0±0.10mg/l; BOD, 3.3±0.09mg/l and alkalinity, 84.1±1.41mg/l. Phosphate and ammonia exceeded FEPA and USEPA acceptable levels for natural aquatic bodies. Phosphate demonstrated significant spatial variation (P＜0.05). The presence of dominant copepods indicates an environment under stress. The domestic and industrial effluents should be recycled or and treated instead of being discharged into this creek.
Opportunities Available and Challenges Faced by Students with Disabilities in Public Universities in Addis Ababa

This study aimed at assessing opportunities available and challenges faced by students with disabilities (SWDs) in public universities in Addis Ababa. To address the objectives of the study, mixed research approach combining both quantitative and qualitative techniques was used. The data was collected through questionnaires, semi-structured interview, focus group discussions (FGDs) and observation. The quantitative data were analysed through descriptive and inferential statistical techniques while the qualitative data was analysed by using the thematic analysis technique. The findings of this study have indicated that availability of reasonable accommodation services, recognition for best scorers, training & induction programs, establishment of special computer centres, provision of educational materials and assistive devices are the opportunities that SWDs have in each respective university. Conversely, inaccessible infrastructures, absence and/or competency problem of sign language interpreters, weak disability affairs offices, unavailability of effective guidance and counselling service, lack of different entertainment means, difficulty of getting personal assistants and different means of communication on academic/non-academic matters are identified as hindrances to their success. The finding of the study also reveals that most lecturers have negative attitudes toward SWDs. The regression result confirms that accessibility of infrastructures, high school GPA, monthly expenditure of students, occupation of parents, disability type and mother’s education are significantly affecting the academic performance of students with disabilities. Therefore, the public universities & other stakeholders should prepare manual and guidelines that show step-by-step processes that need to be taken to address issues of SWDs. Awareness creation schemes need to be carried out to change the negative attitudes and mainstream the issues of SWDs in all endeavours of the respective universities.