Miracle-dz/UniFAR-FTUs huggingface dataset:
Vertical control of DIII-D discharges with strong negative triangularity

Through predictive modeling validated by a series of experiments on DIII-D, the vertical stability of low β diverted plasmas with strong negative triangularity (NT) ( δ∼−0.6 ) is assessed. As a result of their unique magnetic geometry, NT plasmas feature larger Shafranov shifts and more elongated inner flux surfaces than positive triangularity counterparts, typically leading to enhanced vertical instability growth rates. However, coupling with the non-conformal vessel DIII-D wall reduces these growth rates to controllable values, providing a path forward for stabilizing strongly NT plasma with a diverted geometry. These discharges are used to validate GSdesign (part of the TokSys code suite) stability calculations in strong NT plasmas on DIII-D, with errors of no more than ∼20% observed between modeled and experimentally measured growth rates. Additions of diagnostic noise and power supply tuning to the TokSys model are needed to accurately capture the time dependence of DIII-D NT discharges, assisting with the design of control schemes specific to the DIII-D poloidal field coils. Finally, implications of these results on a future NT reactor are briefly described.
Time in Bed, Sleeping Difficulties, and Nutrition in Pregnant New Zealand Women

We consider the relationship between time in bed (TIB) and sleeping difficulties with demographic variables and nutrient intakes in the second (T2) and third (T3) trimester of pregnancy. Data were acquired from a volunteer sample of New Zealand pregnant women. In T2 and T3, questionnaires were administered, diets were obtained from one 24 h recall and three weighed food records, and physical activity was measured with the use of three 24 h diaries. In total, 370 women had complete information in T2 and 310 in T3. In both trimesters, TIB was associated with welfare or disability status, marital status and age. In T2, TIB was associated with work, childcare, education and pre-pregnancy alcohol consumption. There were fewer significant lifestyle covariates in T3. In both trimesters, TIB declined with increasing dietary intake, especially water, protein, biotin, potassium, magnesium, calcium, phosphorus and manganese. Adjusted for weight of dietary intake and welfare/disability, TIB declined with increasing nutrient density of B vitamins, saturated fats, potassium, fructose and lactose; and TIB increased with carbohydrate, sucrose and vitamin E. Subjective sleeping difficulties increased with the week of gestation, morning sickness severity, anxiety, dairy and saturated fat intake, and they decreased with fruit, vegetable and monounsaturated fat intake. The study highlights the changing influence of covariates throughout the pregnancy and corroborates several published findings on the relationship of diet and sleep.
Properties of magnetosheath mirror modes observed by Cluster and their response to changes in plasma parameters

[1] Mirror modes are large amplitude nonpropagating compressive structures frequently observed in the magnetosheath. They appear in the form of quasi-sinusoidal oscillations in the magnetic field, profound magnetic decreases (dips) or magnetic enhancements (peaks), accompanied by a corresponding anticorrelated signature in plasma density. In this study we present an analysis of the properties of mirror mode structures in the magnetosheath of the Earth based on a database of Cluster observations and also a detailed case study of one magnetosheath traversal. We focused primarily on the identification of conditions associated with the magnetic dips and magnetic peaks. It is shown that the character of mirror structures is related to the local degree of instability of the plasma with respect to the mirror instability threshold: peaks are typically observed in an unstable plasma, while mirror structures observed deep within the stable region appear almost exclusively as dips. This observation is found to be consistent with recent theoretical and numerical studies. An abrupt transition of mirror structures from peaks to dips at an approximate distance of 2 Earth radii from the magnetopause was identified by multispacecraft analysis and we interpret this effect as a consequence of plasma expansion in the vicinity of the magnetopause locally changing the plasma conditions towards a more stable state.
Hydrogen/Deuterium Exchange Mass Spectrometry for Probing the Isomeric Forms of Oleocanthal and Oleacin in Extra Virgin Olive Oils

Reversed-phase liquid chromatography and electrospray ionization with Fourier-transform single and tandem mass spectrometry (RPLC-ESI-FTMS and FTMS/MS) were employed for the structural characterization of oleocanthal (OLEO) and oleacin (OLEA), two of the most important bioactive secoiridoids occurring in extra virgin olive oils (EVOOs). The existence of several isoforms of OLEO and OLEA was inferred from the chromatographic separation, accompanied, in the case of OLEA, by minor peaks due to oxidized OLEO recognized as oleocanthalic acid isoforms. The detailed analysis of the product ion tandem MS spectra of deprotonated molecules ([M-H]−) was unable to clarify the correlation between chromatographic peaks and specific OLEO/OLEA isoforms, including two types of predominant dialdehydic compounds, named Open Forms II, containing a double bond between carbon atoms C8 and C10, and a group of diasteroisomeric closed-structure (i.e., cyclic) isoforms, named Closed Forms I. This issue was addressed by H/D exchange (HDX) experiments on labile H atoms of OLEO and OLEA isoforms, performed using deuterated water as a co-solvent in the mobile phase. HDX unveiled the presence of stable di-enolic tautomers, in turn providing key evidence for the occurrence, as prevailing isoforms, of Open Forms II of OLEO and OLEA, different from those usually considered so far as the main isoforms of both secoiridoids (having a C=C bond between C8 and C9). It is expected that the new structural details inferred for the prevailing isoforms of OLEO and OLEA will help in understanding the remarkable bioactivity exhibited by the two compounds.
L p -bounded operators involving generalized hypergeometric functions

We herein determine an integral representation of generalized hypergeometric functions m F m extending the usual results on 1 F 1. After formulating integral operators involving the generalized hypergeometric functions of the form: and we prove that these operators are composition of generalized variants of the Laplace transform (and Watson) and Erdelyi–Kober fractional integral operators. We also prove that these operators are bounded in L p .
New surface flattening scheme and its application in the visualization of the human cortex unfolding

Abstract It is a difficult problem to interpret the spatial relationship between different locations on the human cortical surface. The main reason for this difficulty is that the surface of the human cerebral cortex is highly folded and therefore much of it is obscured from view. In this paper, we present an efficient and distortion‐less flattening algorithm to unfold the cortical surface. Using the proposed technique, we can quickly visualize and precisely measure the cortical surface. Experimental results are shown to evaluate the usefulness of the proposed method.
Awareness of Stroke Risk Factors, Warning Signs, and Preventive Behaviour Among Diabetic Patients in Al-Ahsa, Saudi Arabia

Objectives This study aims to measure the level of awareness about stroke symptoms, risk factors, and preventive health practices that could be taken to reduce the risk of stroke among diabetic patients in Al-Ahsa, Saudi Arabia. Methods A cross-sectional study was conducted in Al-Ahsa, Saudi Arabia in 2020. The sample included a total of 202 male and female Saudi adults aged 18-65 years, with either type 1 or type 2 diabetes mellitus, and living in Al Ahsa, Saudi Arabia. The information was collected randomly through an online questionnaire distributed among patients after getting their contact information from relevant governmental and private diabetes clinics and after signing the informed consent. For awareness and knowledge items, each correct answer was scored one point and the total summation of the discrete scores of the different items was calculated. A diabetic patient with a score less than 60% of the total score was considered to have poor awareness while a score of 60% or more of the total score was considered a good level of awareness. Results A total of 87 (43.1%) participants had an overall good awareness level, while 115 (56.9%) had poor awareness levels. Around 40.6% of the study patients had heard about stroke, 61.9% knew that stroke affects the brain, and 24.3% reported that stroke is higher among males. As for factors associated with stroke, the most reported was high blood pressure (71.8%), followed by diabetes mellitus (69.3%). Exactly 65.8% of participants knew about the mechanism of ischemic stroke and 42.6% reported hemorrhagic stroke. A high percentage of patients (73.1%) realize that they could reduce their risk of stroke. Conclusion The findings of the current study showed that less than half (43.1%) of the Saudi patients with DM had a good awareness level regarding stroke and its related risk factors and warning signs. Older patients (aged 50-65 years) with high social levels (high education and income) and those with a family history of stroke had significantly higher awareness levels. Hypertension, DM, and smoking are the highest reported known risk factors of stroke, and speech disorders are the highest known stroke presentation to the respondents.
Allergenicity and Bioavailability of Nickel Nanoparticles Compared to Nickel Microparticles in Mice

Metal allergy is a common disease that afflicts many people. Nevertheless, the mechanism underlying metal allergy development has not been completely elucidated. Metal nanoparticles might be involved in the development of a metal allergy, but the associated details are unknown. In this study, we evaluated the pharmacokinetics and allergenicity of nickel nanoparticles (Ni-NPs) compared with those of nickel microparticles (Ni-MPs) and nickel ions. After characterizing each particle, the particles were suspended in phosphate-buffered saline and sonicated to prepare a dispersion. We assumed the presence of nickel ions for each particle dispersion and positive control and orally administered nickel chloride to BALB/c mice repeatedly for 28 days. Results showed that compared with those in the Ni-MP administration group (MP group), the Ni-NP administration group (NP group) showed intestinal epithelial tissue damage, elevated serum interleukin (IL)-17 and IL-1β levels, and higher nickel accumulation in the liver and kidney. Additionally, transmission electron microscopy confirmed the accumulation of Ni-NPs in the livers of both the NP and nickel ion administration groups. Furthermore, we intraperitoneally administered a mixed solution of each particle dispersion and lipopolysaccharide to mice and then intradermally administered nickel chloride solution to the auricle after 7 days. Swelling of the auricle was observed in both the NP and MP groups, and an allergic reaction to nickel was induced. Particularly in the NP group, significant lymphocytic infiltration into the auricular tissue was observed, and serum IL-6 and IL-17 levels were increased. The results of this study showed that in mice, Ni-NP accumulation in each tissue was increased after oral administration and toxicity was enhanced, as compared to those with Ni-MPs. Orally administered nickel ions transformed into nanoparticles with a crystalline structure and accumulated in tissues. Furthermore, Ni-NPs and Ni-MPs induced sensitization and nickel allergy reactions in the same manner as that with nickel ions, but Ni-NPs induced stronger sensitization. Additionally, the involvement of Th17 cells was suspected in Ni-NP-induced toxicity and allergic reactions. In conclusion, oral exposure to Ni-NPs results in more serious biotoxicity and accumulation in tissues than Ni-MPs, suggesting that the probability of developing an allergy might increase.
A joint vector and scalar potential formulation for driven high frequency problems using hybrid edge and nodal finite elements

An advanced A-V method employing edge-based finite elements for the vector potential A and nodal shape functions for the scalar potential V is proposed. Both gauged and ungauged formulations are considered. The novel scheme is particularly well suited for efficient iterative solvers such as the preconditioned conjugate gradient method, since it leads to significantly faster numerical convergence rates than pure edge element schemes. In contrast to nodal finite element implementations, spurious solutions do not occur and the inherent singularities of the electromagnetic fields in the vicinity of perfectly conducting edges and corners are handled correctly. Several numerical examples are presented to verify the suggested approach.
The Quiet Sun

An up-to-date textbook of solar physics is presented. The solar structure and processes, and the interior are described along with the photosphere, the chromosphere, and the corona. The strongest Fraunhofer lines, visible coronal lines, and coronal UV, XUV, and X-ray lines are listed.
Effects of Microecological Regulators on Rheumatoid Arthritis: A Systematic Review and Meta-Analysis of Randomized, Controlled Trials

In this study, the available data from published randomized, controlled trials (RCTs) of the use of intestinal microecological regulators as adjuvant therapies to relieve the disease activity of rheumatoid arthritis (RA) are systematically compared. An English literature search was performed using PubMed, Embase, Scopus, Web of Science and the Cochrane Central Registry of Controlled Trials and supplemented by hand searching reference lists. Three independent reviewers screened and assessed the quality of the studies. Among the 2355 citations identified, 12 RCTs were included. All data were pooled using a mean difference (MD) with a 95% CI. The disease activity score (DAS) showed a significant improvement following microecological regulators treatment (MD (95% CI) of −1.01 (−1.81, −0.2)). A borderline significant reduction in the health assessment questionnaire (HAQ) scores was observed (MD (95% CI) of −0.11 (−0.21, −0.02)). We also confirmed the known effects of probiotics on inflammatory parameters such as the C-reactive protein (CRP) (MD −1.78 (95% CI −2.90, −0.66)) and L-1β (MD −7.26 (95% CI −13.03, −1.50)). No significant impact on visual analogue scale (VAS) of pain and erythrocyte sedimentation rate (ESR) reduction was observed. Intestinal microecological regulators supplementation could decrease RA activity with a significant effect on DAS28, HAQ and inflammatory cytokines. Nevertheless, these findings need further confirmation in large clinical studies with greater consideration of the confounding variables of age, disease duration, and individual medication regimens.
Inclusion complexes of squalene with beta-cyclodextrin and methyl-beta-cyclodextrin: preparation and characterization

The present work aimed to investigate inclusion complexes of squalene with various cyclodextrins (native β-cyclodextrin and methyl-β-cyclodextrin). The production of squalene-β-cyclodextrin inclusion complex was obtained using Response Surface Methodology and obtained inclusion complexes were studied with FTIR spectroscopy, X-ray diffractometry, thermal analysis, and 1H-NMR spectrometry. At the same time, squalene content was determined by reversed-phase high-performance liquid chromatography. All results confirmed that squalene was successfully involved in the cyclodextrin cavities. Optimizing the condition in preparation for the squalen-β-cyclodextrin inclusion complex yielded 54.3% with squalene content of 9.01%. The essential difference for the inclusion complex of squalene with methylated beta-cyclodextrin was that no precipitate formed in the initial mixture, and the complex was more efficiently dispersed in water. The conclusions of the inclusion complex formation were confirmed by computer simulation by optimizing the complex geometry using the DFT, MM2, and MP3 methods.
Hydrodynamic pressures on sloping dams during earthquakes. Part 1. Momentum method

Von Kármán's momentum-balance method is adopted to investigate the earthquake forces on a rigid dam with an inclined upstream face of constant slope. The distribution of the hydrodynamic pressure along the upstream face is determined. It is found that the maximum hydrodynamic pressure occurs at the base of the dam for any inclination angle between 0 and 90°. Explicit analytical formulae for evaluating the total horizontal, vertical and normal loads are presented and a useful approximate rule for practical engineers is given.
8–13 µm spectrophotometry of galaxies – II. 10 Seyferts and 3C 273

Les sources observees ne presentent pas de caracteristiques d'emission par la poussiere a l'exception de la galaxie de Seyfert de type 2 NGC 7582 qui presente les raies etroites a 8,65 et 11,25 μm. Deux autres galaxies Seyfert 2, NGC 1068 et 5506 ont des minima proches de 10 μm, attribues a l'absorption par la poussiere de silicate froide. Les autres objets ont des spectres bien representes par des lois de puissance
Thermodynamic Bethe ansatz equations of one-dimensional Hubbard model and high-temperature expansion

A numerical method to calculate thermodynmic Bethe ansatz equations is proposed based on Newton's method. Thermodynamic quantities of the one-dimensional Hubbard model are numerically calculated and compared with high-temperature expansion and numerical results of the quantum transfer matrix method by Juttner, Klumper, and Suzuki. The coincidence is surprisingly good. We obtain the high-temperature expansion of the grand potential up to β 6 .
Can healthcare apps and smart speakers improve the health behavior and depression of older adults? A quasi-experimental study

Purpose This study identified the effects of applying information and communication technologies (ICT) to the health management of older adults aged 65 or older. Methods Older adults registered at public health centers were provided with the health management app “Health Today” and a smart speaker for 6 months to perform assigned healthcare missions. The program was conducted for 6 months by dividing participants into two groups: one that received both the health management app and the smart speaker, and another that used only the health management app. Depression, self-efficacy, number of days of moderate-intensity exercise, relative grip strength, balance tests, and five-times-sit-to-stand tests were measured during the pre- and post-evaluation. Results Both groups showed a positive health status and behavioral changes at post-evaluation. However, no reduced depression was observed due to communication and music listening functions in the group that was additionally provided smart speakers. Conclusion ICT use in healthcare can be beneficial for older adults. However, whether these devices meet the purpose of the national health project must be determined, and an effect evaluation must be undertaken prior to providing these ICT devices for the health management of older adults in the public domain.
Hydrogeochemical characteristics and the genesis of the No. Lu 32 well in the Jiaodong Peninsula, China

The No. Lu 32 well is a seismic observation well situated on the easternmost tip of the Penglai–Weihai fault zone in the Jiaodong Peninsula. It is necessary to reveal the genetic mechanism of the water in this well for earthquake forecasting along the Penglai–Weihai fault zone. Water samples were collected from the No. Lu 32 well, neighboring wells, and seawater to measure the hydrochemical composition and main hydrogen and oxygen isotopic compositions. The water type of the No. Lu 32 well is Cl–Na, which may be due to the influence of seawater intrusion. Hydrogen and oxygen isotopes indicate that the No. Lu 32 well and adjacent wells are mainly influenced by meteoric water, that the high salinity in the water is mainly from the mixing of modern seawater, and that the proportion of seawater there is approximately 5%. Observation of water temperature data in the No. Lu 32 well over several years shows regular annual variations. This comprehensive study shows that the well is greatly affected by seawater backflow infiltration and shallow water. The results of this paper provide an important reference for exploring the hydrogeochemical characteristics and genesis of wells in other coastal zones.
Bounds on Eigenvalues of Interval Matrices

We describe a rectangle in the complex plane enclosing all eigenvalues of an interval matrix. We give theoretical bounds (Theorem 1) that are exact for symmetric or skew‐symmetric matrices, and practical bounds (Theorem 2) requiring evaluation of 4 minimal or maximal eigenvalues and 2 spectral radii of symmetric matrices.
Textiles, basketry and cordage from the Early Neolithic settlement of La Marmotta, Lazio

Abstract Archaeological investigation of Circum-Alpine lake, or pile, dwellings has afforded unprecedented insight into Neolithic and Bronze Age societies. The discovery in 1989 of a submerged settlement near Rome added an early (eighth millennium BP) geographical outlier to this distribution. Two decades of excavation at La Marmotta have identified more than a dozen dwellings and an enormous assemblage of organic remains. Here, the authors present an overview of the textiles, basketry and cordage recovered, and the tools used to manufacture them. The assemblage paints a more complete picture of the technological expertise of Neolithic societies and their ability to exploit and process plant materials to produce a wide range of crafts.
Volatile metabolites from new cultivars of catnip and oregano as potential antibacterial and insect repellent agents

Plant based natural products have been widely used as antibacterial and insect repellent agents globally. Because of growing resistance in bacterial plant pathogens and urban pests to current methods of control, combined with the long- and short-term negative impact of certain chemical controls in humans, non-target organisms, and the environment, finding alternative methods is necessary to prevent and/or mitigate losses caused by these pathogens and pests. The antibacterial and insect repellent activities of essential oils of novel cultivars of catnip (Nepeta cataria L. cv. CR9) and oregano (Origanum vulgare L. cv. Pierre) rich in the terpenes nepetalactone and carvacrol, respectively, were evaluated using the agar well diffusion assay and petri dish repellency assay. The essential oils exhibit moderate to high antibacterial activity against three plant pathogens, Pseudomonas cichorii, Pseudomonas syringae and Xanthomonas perforans of economic interest and the individual essential oils, their mixtures and carvacrol possess strong insect repellent activity against the common bed bug (Cimex lectularius L.), an urban pest of major significance to public health. In this study, the essential oils of catnip and oregano were determined to be promising candidates for further evaluation and development as antibacterial agents and plant-based insect repellents with applications in agriculture and urban pest management.