Miracle-dz/UniFAR-FTUs huggingface dataset:
Dietary Fat Intake: Associations with Dietary Patterns and Postmenopausal Breast Cancer—A Case-Control Study

Simple Summary Breast cancer (BC) is the most common cancer in females worldwide. Although fat has been hypothesized to be involved in BC etiology, the results of available studies are inconclusive. The aim of this study was to assess the associations of dietary fat intake, including an individual’s percentage of energy from dietary fat (Pfat) with peri- and postmenopausal breast cancer (BC) occurrence in women. The associations between Pfat and dietary patterns (DPs) were also examined. The current findings strengthen reports that a higher dietary fat intake may contribute to an increased incidence of BC, which indicates a need to reduce dietary fat intake in cancer prevention. Abstract The aim of this study was to assess the associations of dietary fat intake with BC occurrence and dietary patterns. This case-control study involved 420 women aged 40–79 years from northeastern Poland, including 190 newly diagnosed BC cases. Dietary data were collected using a food frequency questionnaire (62-item FFQ-6®). The Quick Food Scan of the National Cancer Institute and the Percentage Energy from Fat Screener scoring procedures were used to estimate the percentage energy from dietary fat (Pfat). The odds of BC occurrence was three times higher in the Pfat > 32%. The Pfat > 32% was positively associated with the ‘Non-Healthy’ DP and inversely associated with the Polish-aMED® score, ‘Prudent’ DP, and ‘Margarine and Sweetened Dairy’ DP. This case-control study suggests that a higher dietary fat intake (>32%) may contribute to an increased occurrence of peri- and postmenopausal breast cancer in women. Given the obtained results, an unhealthy dietary pattern characterized by the consumption of highly processed, high in sugar foods and animal fat foods should be avoided to reduce fat intake. Instead, the frequent consumption of low-processed plant foods, fish, and moderate consumption of low-fat dairy should be recommended since this pro-healthy diet is inversely associated with dietary fat intake.
The Moderating Effect of Human Capital on the Relationship between Enterprise Risk Management and Organization Performance

In today’s challenging global economy, risk management is encountering a significant transformation. Organizations are switching their risk management method to enterprise-wide from the traditional compartmentalized approach. Enterprise risk management (ERM), which aims at increasing the sustainability of an organization and achieving competitive advantage, is gaining global attention and fast becoming an essential concern in all industries. Despite the importance of the knowledge embedded in people in the current knowledge-based economy, there remains a paucity of evidence concerning how human capital could influence the organization’s ERM. Based on the Resource-based view (RBV) theory, this study analyses the correlation between ERM, human capital, and performance in Malaysian public listed companies (PLCs). For this study, 500 questionnaires had been distributed, and 116 responses were obtained. Structural Equation Modeling (SEM) had been used to assess the fitness of the conceptual model. This study found a significant relationship between ERM and organizational performance, and this relationship is moderated by human capital. This study contributes to the ERM literature by providing empirical evidence on the relationship of ERM, human capital, and organizational performance. Findings from this study also provide guidelines for managers, policymakers, and the regulatory bodies to evaluate the ERM practices in PLCs.
Perspective of nuclear fractal dimension in diagnosis and prognosis of oral squamous cell carcinoma

Background: Owing to the restricted predictive value of conventional prognostic factors and the inconsistent treatment strategies, several oral squamous cell carcinoma (OSCC) patients are still over-treated or under-treated. In recent years, computer-assisted nuclear fractal dimension (nFD) has emerged as an objective approach to predict the outcome of OSCC. Objective: This study is an attempt to find out the differences in nFD values of epithelial cells of normal tissue, fibroepithelial hyperplasia, verrucous carcinoma, and OSCC. Further effort to evaluate the predictive potential of nFD of tumor cells for cervical lymph node metastasis (cLNM) was also assessed. Methodology: Formalin-fixed paraffin-embedded blocks of OSCC tissues of patients treated with neck dissection were collected. Photomicrographs of H-&E-stained sections were subjected to the image analysis by ImageJ and Python programming to calculate nFD. The association of categorical variables with nFD was studied using cross-tabulation procedure and the Fisher exact test. Receiver operating curve analysis was performed to find out cutoff value of nFD. A logistic regression model was developed to test the individual and combined predictive potential of grading and nFD for cLNM. Results: A significant difference between the mean nFD of healthy cells and malignant epithelial cells was observed (P = 0.01). nFD was not found to be an independent predictor of cLNM, although nFD and grading together demonstrated significant predictive potential (P = 0.004). Conclusion: nFD combined with grading can predict lymph node metastasis in OSCC. To the best of our knowledge, this is the first study of its kind.
The unique role of spatial working memory for mathematics performance

We explored the multi-dimensionality of mathematics and working memory (WM) by examining the differential relationships between different areas of mathematics with visual, spatial, and verbal WM. Previous research proposed that visuospatial WM is a unique predictor of mathematics, but neuroimaging and cognitive research suggest divisions within visuospatial WM. We created a new WM task to isolate visuospatial WM’s visual and spatial components and maintained consistent design across tasks and found that spatial WM predicted mathematics and visual WM did not. We also found that verbal WM predicted all mathematics areas included, while spatial WM was a unique predictor of numerical understanding and geometry, not arithmetic and estimation. These findings integrate previous neuroimaging, cognitive and educational psychology research and further our understanding of the relationship between WM and mathematics.
Endoscopic Combined Intrarenal Surgery Versus Percutaneous Nephrolithotomy for Complex Renal Stones: A Systematic Review and Meta-Analysis

Background: Endoscopic combined intrarenal surgery (ECIRS) adds ureteroscopic vision to percutaneous nephrolithotomy (PCNL), which can be helpful when dealing with complex renal stones. Yet, there is still no consensus on the superiority of ECIRS. We aimed to critically analyze the available evidence of studies comparing efficacy, safety, bleeding risk, and efficiency of ECIRS and PCNL. Methods: We searched for studies comparing efficacy (initial and final stone-free rate), safety (postoperative fever, overall and severe complications), efficiency (operative time and hospital stay) and bleeding risk between ECIRS and PCNL. Meta-analysis was performed. Results: Seven studies (919 patients) were identified. ECIRS provided a significantly higher initial stone-free rate, higher final stone-free rate, lower overall complications, lower severe complications, and lower rate of requiring blood transfusion. There was no difference between the two groups in terms of postoperative fever, hemoglobin drop, operative time, and hospital stay. In the subgroup analysis, both minimally invasive and conventional ECIRS were associated with a higher stone-free rate and lower complication outcomes. Conclusions: When treating complex renal stones, ECIRS has a better stone-free rate, fewer complications, and requires fewer blood transfusions compared with PCNL. Subgroups either with minimally invasive or conventional intervention showed a consistent trend.
Factors influencing quality of life in low-income women with young children in Korea: a cross-sectional study

Purpose This study aimed to investigate the effects of health-promoting behaviors (HPB), marital intimacy, and parenting stress on the quality of life (QoL) of low-income women with young children in Korea, an underserved group. Methods This cross-sectional survey employed a descriptive correlational design. Using convenience sampling, 123 low-income women with children younger than 6 years were recruited from 14 health and community centers in Jeonju, Korea, from June 2020 to May 2021. Participants completed a questionnaire on QoL, HPB, marital intimacy, and parenting stress. Data were analyzed using descriptive statistics, independent t-test, analysis of variance, Pearson correlation, and hierarchical regression analysis. Results Participants, who were on average 37.41±3.65 years old and had 1 to 2 children (n=98, 79.7%), reported a mid-level (3.14 out of 1–5) of QoL. Marital intimacy (β=.38, p<.001) was the most influential factor on the QoL of low-income women with young children. In descending order, HPB (β=.35, p<.001) and non-employment status (β=–.21, p=.003) had a significant influence on QoL (F=15.64, p<.001), and the overall explanatory power was 49.0%. Conclusion Considering the mid-level QoL of low-income women with young children, programs aimed at improving the QoL of low-income women need to promote marital intimacy and maintain HPB, while considering their employment status. Strategies that include couple counseling, health care to encourage healthy lifestyles, and reemployment education are needed.
Patient Outcomes from Student-Run Health Services: An Integrative Review

Background Student-run clinics (SRCs) offer an innovative approach to expand healthcare access and equity and increase clinical placement opportunities for students. However, research on the health benefits and/or outcomes of such clinics is currently fragmented. Methods An integrative review was conducted to capture and synthesize findings across a range of study types involving varied student disciplines, student delivered intervention types, and health conditions addressed or care areas of focus. Only published and peer reviewed studies were included. Studies needed to report outcomes in a defined study group measured over time, or report SRC data with explicit comparisons to non-SRC settings. Data were analyzed using inductive content analysis to identify major themes and natural clustering of health outcomes measured. Results Fifty-one articles were selected for review based on the eligibility criteria. Studies were predominantly from the United States, and most (n = 34, 67%) adopted a case review methodology for measuring outcomes. Health outcomes were evaluated in relation to a range of health conditions that, for the purposes of this review, were considered to naturally cluster into eight categories: diabetes, hypertension, functional health/quality of life, depression, hospital utilization, substance use, weight, health screening/vaccinations, and others. Conclusion This integrative review sought to evaluate the health outcomes accrued by patients in student-run health clinics. Taken as a whole, the literature suggests positive health outcomes resulting from student-run clinics across a range of health conditions. Greater confidence in care-related findings would be achieved from future research utilizing more robust and prospective study designs.
Effect of different dipeptidyl peptidase-4 inhibitors on lipid profile of type II diabetic patients

Objective: In this research study, we aimed to study the effect of dipeptidyl peptidase-4 inhibitors (Gliptins drug) on the lipid profile of diabetic type 2 patients. Materials/methods: Type 2 diabetic (200) patients taking Gliptin ± metformin and willing to participate in the study were included. Lipid profile tests (total cholesterol, HDL, non-HDL, LDL, VLDL, triglycerides level) of the patients were done in a pathological laboratory on routine health checkups. The mean and S.E. M of each parameter were calculated. All data were subjected to a Student's t-test. Comparison between the treatments was done by using one-way ANOVA- Bonferroni multiple comparison tests. Results: All 200 patients have completed the questionnaire and monitored twice for six months (initial visit and final visit). Of the total participants, 109 (54.50%) were males and 91 (45.50%) were females. Ninety tow (46%) were taking vildagliptin + metformin while 73 (36.5%) patients were taking vildagliptin, 20 (10%) were taking sitagliptin + metformin, 15 (7.5%) were taking linagliptin and only 1 (0.5%) patients were taking sitagliptin. Conclusions: The present findings showed that vildagliptin can reduce the total cholesterol level, Non-HDL level, and triglycerides significantly. Linagliptin can reduce the total cholesterol Level and non-HDL significantly.
Dividend Policy Determinants and Stock Price Volatility in Selected African Stock Markets

The study examined the impact of dividend policy determinants on stock price volatility in Sub Sahara Africa. Three (3) economies (Nigeria, Kenya and South Africa) were selected from among the 51 economies in the region, and data spanning 9 years (2011-2019) were obtained and subjected to econometric analyses. The Generalized Autoregressive Conditional Heteroskedacity (GARCH) was used to ascertain and generate the volatility properties of the stock prices, while the panel Autoregressive Distributed Lag (ARDL) technique was used to capture the relationship between dividend policy determinants and stock price volatility. The independent variables analyzed in this study are leverage (LEV), firm size (FSIZE), dividend yield (DY), earnings per share (EPS) and dividend payout (DPO) while the dependent variable was the volatility in stock price (SPV). Findings show that all of the variables considered have varying degree of relationships with stock price volatility both in the long run and short run in the three countries. The pooled result indicated that DPO, LEV, FSIZE, DY and EPS had a significant relationship with stock price volatility within the study period in the long run but no short run relationship could be confirmed for the combined samples. The study concluded that dividend payout, dividend yield and earnings per share are significant factors that can be used for predicting the volatile movement in stock price in the African stock markets. The study recommended that dividend payment should be consistent and smoothed to disrupt volatility of stock prices since dividend payment is found to be significant determinant of stock price volatility.
A Retrospective Study on the Predictors of Outcome in Patients with Infective Endocarditis

Background : Infective endocarditis (IE) is associated with signi ﬁ cant mortality and morbidity. This study aims to up-date the epidemiology of IE and to identify predictors of adverse outcome in the Chinese population in Hong Kong. Methods : This was a single-centre retrospective study of patients diagnosed with IE in Princess Margaret Hospital in Hong Kong during 2002 e 2016. Primary outcome was de ﬁ ned as in-hospital mortality. Secondary outcomes included 1-year mortality, valvular surgical intervention, heart failure, stroke and systemic embolization. Results : In total, 196 patients with de ﬁ nite or possible IE were included in the study. The incidence of IE was 2.26 per 100,000 person-years and had remained stable. Health care-associated IE (HCAIE) accounted for 32% of cases, with an increasing trend. Staphylococcus aureus was the most frequently isolated organism in the overall study population (37.8%) and among intravenous drug users (85.2%). In-hospital mortality remained high (29.1%) and was independently associated with higher Charlson Comorbidity Index (OR 1.24, p ¼ 0.001), heart failure (OR 5.65, p < 0.001) and the presence of large vegetation ≥ 1 cm (OR 4.67, p < 0.001). IE due to Streptococcus viridans was associated with a better outcome (OR 0.40, p ¼ 0.048). Discussion : This study showed that the incidence of IE remained stable during 2002 e 2016. There was an increasing proportion of HCAIE and S. aureus has become the most common causative organism. IE was associated with high mortality and morbidity. Independent predictors for in-hospital mortality were patient ' s medical comorbidity, large vegetation size and heart failure, while infection by viridans group streptococci was associated with reduced risk.
The Brain Dynamics of Syllable Duration and Semantic Predictability in Spanish

This study examines the neural dynamics underlying the prosodic (duration) and the semantic dimensions in Spanish sentence perception. Specifically, we investigated whether adult listeners are aware of changes in the duration of a pretonic syllable of words that were either semantically predictable or unpredictable from the preceding sentential context. Participants listened to the sentences with instructions to make prosodic or semantic judgments, while their EEG was recorded. For both accuracy and RTs, the results revealed an interaction between duration and semantics. ERP analysis exposed an interactive effect between task, duration and semantic, showing that both processes share neural resources. There was an enhanced negativity on semantic process (N400) and an extended positivity associated with anomalous duration. Source estimation for the N400 component revealed activations in the frontal gyrus for the semantic contrast and in the parietal postcentral gyrus for duration contrast in the metric task, while activation in the sub-lobar insula was observed for the semantic task. The source of the late positive components was located on posterior cingulate. Hence, the ERP data support the idea that semantic and prosodic levels are processed by similar neural networks, and the two linguistic dimensions influence each other during the decision-making stage in the metric and semantic judgment tasks.
Immune suppressive microenvironment in brain metastatic non-small cell lung cancer: comprehensive immune microenvironment profiling of brain metastases versus paired primary lung tumors (GASTO 1060)

ABSTRACT Lung cancer is one of the most common causes of brain metastases and is always associated with poor prognosis. We investigated the immunophenotypes of primary lung tumors and paired brain metastases, as well as immunophenotypes in the synchronous group (patients with brain metastases upon initial diagnosis) and metachronous group (patients developed brain metastases during the course of their disease). RNA sequencing of eighty-six samples from primary lung tumors and paired brain metastases of 43 patients was conducted to analyze the tumor immune microenvironment. Our data revealed that matched brain metastases compared with primary lung tumors exhibited reduced tumor infiltrating lymphocytes (TILs), a higher fraction of neutrophils infiltration, decreased scores of immune-related signatures, and a lower proportion of tumor microenvironment immune type I (high PD-L1/high CD8A) tumors. Additionally, we found a poor correlation of PD-L1 expression between paired brain metastases and primary lung tumors. In addition, gene set enrichment analysis (GSEA) showed that some gene sets associated with the immune response were enriched in the metachronous group, while other gene sets associated with differentiation and metastasis were enriched in the synchronous group in the primary lung tumors. Moreover, the tumor immune microenvironment between paired brain metastases and primary lung tumors displayed more differences in the metachronous group than in the synchronous group. Our work illustrates that brain metastatic tumors are more immunosuppressed than primary lung tumors, which may help guide immunotherapeutic strategies for NSCLC brain metastases.
Content of Enzymatic and Nonenzymatic Antioxidants in Salix viminalis L. Grown on the Stebnyk Tailing

Currently, the problem of environmental pollution, especially in contaminated areas, is highly important. The study of the defense mechanisms of plants under salt stress (high salinity) is of considerable importance, given the conditions of current agricultural development and climate change. The aim of this study was to reveal the effect of salinity on Salix viminalis L. under field conditions at the Stebnyk tailing site in Ukraine. After 120 days of growth, the leaves, stems, and roots of S. viminalis were harvested to measure the antioxidant defense system of plants under salinity. Inhibition of S. viminalis growth was observed. We found that peroxidase, ascorbic acid, and proline mainly accumulated in the stems of S. viminalis under salinity conditions. However, in the roots, an increase in catalase activity and soluble sugars content was observed under salinity stress. Thus, the increase in the amount and changes in the activity of enzymes showed the involvement of the antioxidant system in the adaptation of S. viminalis to salinity. The data obtained in this study serve as a starting point for understanding the adaptive mechanisms of S. viminalis to salinity, particularly at the Stebnyk tailing. We believe our findings will support the use of plants in nature-based solutions and eco-engineering projects on saline and industrially polluted lands.
Factors Affecting Asian Corn Borer Emergency Size and Its Forecast

Asian com borer(ACB) is distributed over East Asian and Oceania. The author anal-ysed the main factors such as over winter population structure and envirorunental condition, metcorologi-cal condition before over winter larea pupate, meteo ralogical condition in fields on the stage of ACBemergency and hostplant. By summing up the data at home and abroad and the author's previousresearch work . The author also proposed the problem existed in forecast work and made suggestions forrevision.
A comparison of project control standards based on network analysis

Project control is a crucial function in project management. Over the years, several best practice standards have been developed to assist project managers in improving project control. The objective of this paper is to compare three prominent best practice models of PMBOK, PRINCE2, and the AACE framework with respect to the core processes of project control. Network analysis is used to achieve this objective. The results show that influential and linkage processes, such as Control quality, Review the stage status, Forecasting, and Change management have the most significant impacts on the complexity of the project control function. This work has the potential to help rethink the project control function by creating a more global view of the most central and critical processes for project control, from which enhancement in the ability to control the project can be drawn.