Miracle-dz/UniFAR-FTUs huggingface dataset:
LEVEL OF SERUM IRON AND ZINC IN CHILDREN AND ASSESSING ITS CORRELATION WITH SIMPLE FEBRILE SEIZURE-A PROSPECTIVE OBSERVATIONAL STUDY

Background: Febrile seizures are one of the most common paediatric emergencies encountered around the world. Febrile seizures occur in 6 months to 60 months of age group. Iron and zinc are important trace elements and some enzymes and neurotransmitters in the central nervous system are affected by its levels. Inhibitory mechanisms in the brain could be affected by its deficiency and thus producing convulsion. Aims and Objectives: To estimate the serum level of zinc in children and assessing its correlation with simple febrile seizure. To estimate the serum level of iron in children and assessing its correlation with simple febrile seizure. Materials and Methods: Prospective Observational study conducted at Department of Pediatrics, Katihar Medical College, Katihar. The study included 61 children between 6 months and 60 months of age admitted with simple febrile seizure. Their serum iron and zinc and various other parameters including Hb, MCV, MCH, MCHC were determined. Data were analyzed by SPSS 20, frequency, mean, standard deviation, chi square test and independent sample t test. Result: A total of 61 children were included in the study. The prevalence of iron and zinc deficiency in children with simple febrile seizure was found to be 65.5% and 57.3% respectively. There was no statistically significant difference in all the parameters between children with Iron deficiency and without Iron deficiency presenting with simple febrile seizures. Conclusion: The findings suggest that a considerable percentage of
ROLE OF DWI IN INTRACRANIAL PATHOLOGIES WITH ITS COMPARISON TO FLAIR AND T2W IMAGING

Introduction: Diffusion-weighted MRI sequence is a special and advanced MRI technique that depends on the random movement of water molecules within and between the intracellular and extracellular spaces. Image contrast in diffusion-weighted images is dependent on the molecular motion of water. Conventional MR provides information like visualization of a mass lesion, information on mass location, its homogeneity, and signal intensity, the presence of perilesi onal edema, and degree of contrast enhancement, but In conventional MRI imaging, staging of brain stroke and hematoma, cellularity, architecture, tumor grade, aggressiveness, histological criteria of the tumor cannot be evaluated, for this purpose diffusion-weighted sequence is required. Aims and objective: We aim to analyse the role of DWI in the evaluation of intracranial lesions by describing the features of intracranial lesions on diffusion-weighted imaging and comparing them with ADC and T2/FLAIR images so as to help differentiate among them. We aim to characterize the staging of acute brain ischemia, diagnose white matter diseases, differentiate cystic SOLs, and differentiate a multitude of Infections inflicting the central nervous system. Method and Material: The study was carried out in the Department of Radiodiagnosis, at G.G hospital, Shri M.P. shah government medical college with 100 patients who underwent DWI and conventional MR imaging of the brain during the period of 12 months. Participants after understanding the study protocol and procedure were asked to give their written consent for the study. Result: Out of 100 patients (age ranging from 14 days to 95 years), out which 28 patients having infarcts with or without hemorrhagic transformation were studied in which sensitivity and specificity of DW imaging was 100% within the initial 6 hours, which is far more superior than conventional MR imaging. Amongst the patients with brain tumors, variable patterns of diffusion were noted. This variability can be attributed to the varying cellularity of different tumors. Although subgroups like gliomas, meningioma, and metastasis showed consistency with other comparative studies. There were patients with cystic SOLs and demyelinating disorders that showed imaging findings consistent with other comparative studies reaffirming the role in their characterization, except for a few inconsistent lesions in patients with multiple sclerosis. Conclusion: Diffusion-weighted MRI provides magnanimous strides in the characterization of the intracranial lesion and immensely facilitates T2-weighted and FLAIR imaging techniques.
AUTOMATED ASSESSMENT OF COMPLEX TASK PERFORMANCE IN GAMES AND SIMULATIONS

Assessment of complex task performance is crucial to evaluating personnel in critical job functions such as Navy damage control operations aboard ships. Games and simulations can be instrumental in this process, as they can present a broad range of complex scenarios without involving harm to people or property. However, automatic performance assessment of complex tasks is challenging, because it involves the modeling and understanding of how experts think when presented with a series of observed in-game actions. When assessing performance, human expert scoring can be limiting, as it depends on subjective observations of in-game player’s performance, which in turn is used to interpret their mastery of key associated cognitive constructs. We introduce a computational framework that incorporates the automatic performance assessment of complex tasks or action sequences as well as the modeling of real-world, simulated, or cognitive processes by modeling player actions, simulation states and events, conditional simulation state transitions, and cognitive construct dependencies using a dynamic Bayesian network. This novel approach combines a state-space model along with a probabilistic framework of Bayesian statistics, which allows us to draw probabilistic inferences about a player’s decision-making abilities. Through this process, a comparison of human expert scoring and dynamic Bayesian network scoring is presented. The use of the computational framework using a dynamic Bayesian network presented in this report can help reduce or eliminate the need for human raters and decrease the time to score. This has the benefit of potentially reducing costs. In addition, it can facilitate the efficient aggregation, standardization, and reporting of the scores.
Trajectory-Enhanced AIRS Observations of Environmental Factors Driving Severe Convective Storms

We investigate environmental factors of severe convective weather using temperature and moisture retrievals from the Atmospheric Infrared Sounder (AIRS) that lie along parcel trajectories traced from tornado, large hail, and severe wind producing events in the central United States. We create AIRS proximity soundings representative of the storm environment by calculating back trajectories from storm times and locations at levels throughout the troposphere, using the Hybrid Single Particle Lagrangian Integrated Trajectory (HYSPLIT) model forced with the 32-km North American Regional Reanalysis (NARR) and 12-km North American Mesoscale Forecast System (NAM12). The proximity soundings are calculated for severe weather events including tornadoes, hail ≥2 in. diameter, and wind gusts >65 mph (29 m s−1) specified in the NCEI Storm Events database. Box-and-whisker diagrams exhibit more realistic values of enhanced convective available potential energy (CAPE) and suppressed convective inhibition (CIN) relative to conventional “nearest neighbor” (NN) soundings; however, differences in lifting condensation level (LCL), level of free convection (LFC), and significant tornado parameter (STP) from the HYSPLIT-adjusted back traced soundings are more similar to NN soundings. This methodology should be extended to larger swaths of soundings, and to other operational infrared sounders, to characterize the large-scale environment in severe convective events.
Knowledge, Beliefs and Attitude towards Sickle Cell Disease among Students of Kampala International University Jinja Teaching Site Uganda

Sickle cell disease (SCD) is one of the most widespread hereditary disorders among the African lineage. SCD is associated with recurrent severe pain, increased morbidity and mortality yet has received less recognition in the public domain. Evidence of the need to increase awareness to reduce the disease incidence is increasing due to the rising incidence of this preventable disease. This study aimed to describe the knowledge, beliefs and attitude towards SCD of students at Kampala international university. A descriptive cross-sectional study design was employed. A total of 384 university students participated in the study, and using a semi-structured questionnaire, information was collected from participants on demographic characteristics, general knowledge of SCD, and beliefs and attitudes of students towards SCD. Nearly all the students were aware of SCD (99.2%). Knowledge level of respondents on SCD based on scores revealed a mean score of 9.7± 4.5 with 65%, 30%, and 5% for poor, moderate and excellent respectively. Most of the respondents strongly agreed that they feel worried (52.9%) and sympathetic (51.3%) for people affected with SCD. Participants had the belief that it is an inherited disease acquired from parents (48.2%) but not a punishment from God (76.3%). In general, there was a limited understanding and inadequate knowledge of SCD among the students particularly on the pattern of inheritance. Results from the study highlights the need for effective public health education on SCT/SCD in trusted sources such as schools, media (radio/Television), health centres and churches. This is necessary to address misconceptions and increase knowledge level as well as an understanding of the risks of having a child with SCD to influence personal reproductive options. Keywords: Sickle cell disease, Parents, Students, Child, Preventable disease.
Co-Infection of Covid-19 with Dengue and Chikungunya: A Study from a Tertiary Care Hospital (preprint)

Purpose The present study is aimed to identify the co-infection of Covid-19 with Dengue and/or Chikungunya. The present study was conducted from June 2021 to August 2021.Method 125 serum samples were collected from febrile patients of all age groups suffering from cold and fever. These samples were tested for the presence of Covid-19 antibodies. The Covid-19 positive sample were tested for the Dengue and/or Chikungunya infections by using IgM ELISA.Results Among 125 samples, 91 samples were tested positive for SARS-CoV-2 antibodies. In these 91 Covid-19 positive samples, 3 samples were Dengue IgM positive and 14 were positive for Chikungunya by IgM ELISA.Conclusion In the present study, antibodies against CHIKV, DENV were detected in Covid-19 positive patients. 14 cases of coinfection between Covid-19 and Chikungunya and 3 cases of coinfection between Covid-19 and Dengue were reported from the present study.
A CADAVERIC STUDY ON ROUVIERE’ S SULCUS – MORPHOLOGY & MORPHOMETRIC STUDY

Background: The liver is the largest abdominal viscera, divided into right, left, caudate & quadrate lobes by peritoneal and ligamentous attachments. Rouviere's sulcus (RS) is present in the posterior surface of the liver and acts as an anatomical landmark for safe liver dissection and a surgical landmark for Laparoscopy cholecystectomy. Knowledge about surgical anatomy is important for the safe execution of any surgical procedure. The study aims to enumerate the presence or absence of sulcus, types of the sulcus (Type 1, Type 2 & Type 3) & morphometric measurement of Rouvier's sulcus (Length & Breadth). Materials and Methods: An observational study was conducted with 52 macroscopically healthy and undamaged liver specimens removed during routine dissection from both sexes while teaching undergraduate medical students. The specimens were washed, dried, numbered, and stored in formalin-filled containers. They were examined for the presence or absence of RS and the type of sulcus if present. Result: Rouviere's sulcus (RS) was found in 47 specimens, classified as Type 1, 2, and 3. Type 1 RS was found in 30 specimens, Type 2 RS in 8 specimens, Type 3 in 9 specimens, Type 1A sulcus in 26 specimens, and Type 1B in 4 specimens. RS was absent in 5 specimens, and the average length and breadth of the sulcus were 2.6 cm and 0.3 cm, respectively. Conclusion: RS is a landmark for identifying and isolating the CBD
Haematological parameters of leiomyomatous Wistar rats administered a mechanically-engineered drug pellets doses of Spondias mombin and Curcuma

Uterine leiomyoma is popularly known as fibroid. It is the most common myometrial tumour ravaging African women of child-bearing age and has enormous socio-economic and health consequences. The disease develops earlier and faster in black women than other races and scientifically this disparity is not understood. This work investigated effects of oral intake of pellets prepared as chemotherapy from aqueous extracts of Spondias mombin and Curcuma longa on female Wistar albino rats with monosodium glutamate-induced leiomyoma. Drug pellets from these samples were produced through a mechanically engineered process and the research objective was to investigate possible effects of these pelleted drugs on haematological parameters of leiomyomatous rats after oral administration. Twenty-four rats acclimatized for two weeks and divided into four groups of six rats each were used for this study. Leiomyoma was induced on rats in groups II to IV with the daily administration of 750mg/kgbw pellets of MSG for twenty-eight (28) days. Groups III and IV rats continued to receive formulated MSG pellets with the different extracts in the second twenty-eight (28) days. The neutrophil and eosinophil levels of control II rats increased significantly in weeks 3 (29.20±3.49, 3.00±1.00) and 4 (31.60±2.07, 5.60±0.55), compared to that of control I and group IV rats (25.20±2.28, 1.40±0.55; 25.00±2.12, 1.20±0.45). Lymphocyte levels of control II rats decreased significantly (P≤0.05) in weeks 3 (55.60±3.78) and 4 (50.60±3.21) when compared to group IV. The level of red blood cells decreased significantly (P≤0.05) in all groups except control I compared to white blood cell levels which decreased significantly (P≤0.05) in group IV. The 750mg/kgbw pellets prepared from Curcuma longa water extract alleviated MSG effect on fibroid compared to Spondias mombin .
Improving the Loyalty of Customer through the Effectiveness of Customer Satisfaction, Service Quality, and Food Quality

The food industry is one of the business sectors that is future-oriented, as evidenced by food being one of the basic needs of the community. Therefore, it is necessary to examine customer loyalty in the food industry through the role of customer satisfaction, service quality and food quality, as in this study. In developing this research, quantitative descriptive methods were used by involving a sample of 100 respondents to obtain analysis data, which was then processed and analyzed using SEM-PLS. The research reveals that there is a significant positive correlation occurred of service quality along to food quality which affecting customer satisfaction. And this customer satisfaction also affects in increasing customer loyalty to Subway Indonesia. These results indicates that Subway Indonesia needs to maintain their improvement on service quality and food quality which served based on consumers expectations, so as to increase customer satisfaction and loyalty.
Prevalence of wheat allergy in Al-Kharj, Saudi Arabia.

BACKGROUND Wheat allergy has been suggested to represent an important allergic disease. This study collates clinical and laboratory aspects in patients with wheat allergy in Al-Kharj city, Saudi Arabia. METHODS Total and specific IgE were measured in 15 suspected cases of wheat allergy. Protein allergenicity was assessed with Western blotting. RESULTS Significant elevation of total and specific IgE was found in 4 cases. Basophlia was also demonstrated on blood film. Western blotting results showed 2 bands (83 and 40 kDa). CONCLUSION Wheat allergy must also be considered when planning treatment of asthma and eczema of adult patients.
The Corporate Propensity to Save

Why do corporations accumulate liquid assets? We show theoretically that intertemporal trade-offs between interest income taxation and the cost of external finance determine optimal savings. Intriguingly, we find that, controlling for Tobin's "q", saving and cash flow are negatively related because firms lower cash reserves to invest after receiving positive cash-flow shocks, and vice versa. Consistent with theory, we estimate negative propensities to save out of cash flow. We also find that income uncertainty affects saving more than do external finance constraints. Therefore, contrary to previous evidence, saving propensities reflect too many forces to be used to measure external finance constraints. Copyright (c) 2009 the American Finance Association.
THE INFLAMMATORY FINGERPRINT OF CORONARY ARTERY DISEASE – A PROSPECTIVE OBSERVATIONAL STUDY

Background: The pathophysiology of atherosclerosis is significantly influenced by inflammation. We have investigated the correlation of hs-CRP levels with clinical profile and coronary artery disease angiographic severity. Materials and Methods: This study was performed at Department of cardiology Govt. Stanley medical college. Fifty patients (37 males and 13 females) with angiographically assessed CAD were involved in this study. The severity of each patient's CAD was assessed using vascular scoring. Lipid profile and high sensitivity C-reactive protein (hs-CRP) were analysed. Results: The age of 50 patients was 58.72 ±12.81 years and comprised 74% males and 26% females. Angiographic findings of the patients demonstrated that the prevalence of single vessel disease (SVD), double vessel disease (DVD), and triple vessel disease (TVD) were 42%, 36%, and 22%, respectively. Based on the hs-CRP cut-off value, patients were subdivided into high levels (hs-CRP < 3 mg/L) and low levels groups (hs-CRP > 3.1 mg/L), which indicated that 71.4%, 44.4%, and 18.2% of patients had SVD, DVD, and TVD, respectively in hs-CRP <3 Category, whereas 28.6%, 55.6%, and 81.8% of patients had SVD, DVD, and TVD, respectively, in the hs-CRP >3.1 categories. Both groups of high-and low-hs-CRP levels were compared, which showed a significant difference in both categories (p=0.014). Conclusion: We conclude that hs-CRP levels are significantly higher in patients with angiographically detected CAD and are associated with the existence and severity of CAD.
Conflictual Rebordering: The Russia Policies of Finland and Estonia

This article seeks to analyse the process of conflictual rebordering in the EU’s relations with Russia. The authors single out three major crises that triggered and shaped the process of toughening the border regime and the related transformations of political meaning of the EU-Russia border: the COVID-19 pandemic, the drastic deterioration of Moscow-Brussels relations in the beginning of 2021 and the war in Ukraine that started on 24 February 2022. Correspondingly, the EU’s reactions to each of these critical junctures might be described through the academic concepts of governmentality, normativity and geopolitics. Our aim is to look at the three ensuing models – governmental, normative and geopolitical rebordering – from the vantage point of Estonia and Finland, two EU member states sharing borders with Russia, yet in the meantime remaining distinct from each other in developing particular border policies and approaches vis-a-vis their eastern neighbour.
PRESERVATIVE FREE SODIUM HYALURONATE 0.15% IN DRY EYE DISEASE PATIENTS TREATED WITH PROSTAGLANDIN ANALOGUES FOR PRIMARY OPEN-ANGLE GLAUCOMA IN KASHMIR: A PROSPECTIVE STUDY

Purpose: Dry eye disease (DED) can be triggered using preserved ophthalmic formulations or prostaglandin analogues. In this prospective study, we evaluated the efficacy of a 0.15% hyaluronic acid (HA) non preserved ophthalmic formulation in decreasing DED symptoms in Kashmiri population with open-angle glaucoma treated with prostaglandin analogues. Materials and Methods: 50 patients with DED receiving chronic treatment with prostaglandin analogues for primary open-angle glaucoma or ocular hypertension were administered ophthalmic formulations 3 times daily for 12 weeks. Foreign body sensation, burning, stinging, dryness, pain, frequency of symptoms, conjunctival hyperaemia, corneal fluorescein staining (CFS), tear film break-up time (TBUT), best-corrected visual acuity, Schirmer test results between the baseline and 4 and 12 weeks were evaluated. Result: The analysis shows that all primary endpoints improved; in particular, burning sensation and the frequency of symptoms after 4 and 12 weeks of treatment (p < 0.001) and dryness and pain after 12 weeks of treatment (p < 0.001 and p = 0.03, respectively) were reduced significantly. Secondary outcomes confirmed the positive results, with a statistically significant change in the CFS between the baseline and 4 (p = 0.02 and p < 0.001, respectively) or 12 weeks (both p < 0.001) and TBUT after 4 weeks (p = 0.01). Conjunctival hyperaemia improved in both eyes in >90% of cases at 12 weeks of treatment. Conclusion: The present study shows that the ophthalmic formulation containing 0.15% HA has a promising beneficial effect on reducing the signs and symptoms of DED in Kashmiri population treated with prostaglandin analogues.
RETROSPECTIVE ANALYSIS OF PREVALENCE OF BRAIN METASTASIS IN VARIOUS CANCERS AND THEIR SURVIVAL– INSTITUTIONAL EXPERIENCE

Background: Brain metastasis (BM) is the most common intracranial tumor in adults, with an incidence of 20% to 40%. Though it is most common in lung cancer, 20% may present upfront with BM, as in melanoma. Multiple site metastases are commoner, with most common site being the cerebral hemisphere (80%). The study's objective is to analyse the prevalence of brain metastasis in various cancers and their survival. Materials and Methods: One hundred thirty-six patients diagnosed with brain metastasis in our institution from 2018 to 2022 were analysed retrospectively. The prevalence, progression-free survival(PFS) and overall survival(OS) were calculated. Result: The median age of presentation was 56 years, with female preponderance. Of 136 patients, 47% had lung primary, and 29% had breast primary. The most common sites of brain metastasis are the cerebral hemisphere(85%), cerebellum(32%) and brain stem(7%). About 28% had solitary brain metastasis, most in the frontal region. On analysis, the prevalence of brain metastasis in lung cancer has increased from 9% in 2018 to 16% in 2021. PFS for cervix, lung and breast carcinoma were 2-3 years, ten months and 1-4 years respectively and for ovary and rectum carcinoma ranges from 3 to 8 years. Of 76 patients who received whole brain radiotherapy, OS for lung cancer is less than 12 months, breast carcinoma is 2-5 years, and melanoma is six months. Conclusion: The factors like the primary site, upfront presentation, multiple-site brain metastasis, molecular markers and extracranial metastasis affect PFS and OS.
Primary gastric leiomyosarcoma: a case report and literature review

of 5.1 g/dL. Endoscopy revealed a huge subepithelial mass in the posterior wall of the gastric body. Contrast-enhanced computed tomographic images showed an intraluminal protruding enhancing mass with an internal stalk appearance in the gastric body. There was no internal necrosis or calcification. The patient underwent subtotal gastrectomy and was diagnosed with primary gastric LMS. The diagnosis of gastric LMS is challenging due to its rarity. Our case report suggests that the presence of an internal stalk or spouting appearance can help prompt the radiologist to consider gastric LMS in the differential diagnosis.