Miracle-dz/UniFAR-FTUs huggingface dataset:
PPA_A_289139 99..110

1US Medical Affairs, AstraZeneca, Gaithersburg, MD, USA; 2US Patient Safety, AstraZeneca, Wilmington, DE, USA; 3Kantar, Health Division, New York, NY, USA; 4Kantar, Health Division, Horsham, PA, USA; 5Kantar, Health Division, St. Louis, MO, USA; 6Division of Hematologic Malignancies and Cellular Therapy, Duke University, Durham, NC, USA Purpose: Treatment for chronic lymphocytic leukemia (CLL) has changed dramatically with the approval of novel agents. Information regarding how patients and oncologists make trade-offs across attributes of novel therapies is limited. The purpose of this study was to understand how variations in attributes impact treatment choice among patients and oncologists. Patients and Methods: In this study, 371 participants (patients [n=220] and oncologists [n=151]) completed an online discrete choice experiment (DCE) to quantify preferences for first-line (1L) CLL treatment with novel agents; participants chose between hypothetical treatment profiles consisting of eight attributes with varying levels taken from published literature. Hierarchical Bayesian models were used to estimate attribute level preference weights. The weights were used to compute relative importance, a measure of how influential an attribute is to treatment choice. Results: Increasing 2-year progression-free survival (PFS) from 75% to 95% had the greatest impact on preferences in 1L CLL treatment, accounting for 40% and 30% of the variation in preferences among patients and oncologists, respectively. Risk differences in atrial fibrillation (AF), infection, and discontinuation due to adverse events (AEs) were also important to patients and oncologists. Among both groups, risk differences in tumor lysis syndrome (TLS) and bleeding were least influential in treatment choice. Oncologists required 2–4 times higher increases in 2-year PFS than patients to accept increased risks of AF, discontinuation due to AEs, bleeding, TLS, and arthralgia/myalgia. Conclusion: Patient–oncologist communication may be improved by a more focused discussion on the risks of AEs, relative to treatment outcomes, with patient goals in mind.
Survey of apple collar and rootstock blight in Serbia

Apple production in Serbia is characterized by the introduction of new technologies and the establishment of intensive plantations based on modern systems. In intensive apple production systems, sudden and rapid decay of young apple trees exhibiting collar and rootstock blight symptoms in the first few years after planting is becoming a prevalent issue. However, knip or nursery trees with lateral branches (feathers) on rootstock M.9 i.e. oneto five-year old are most seriously affected. Based on a longitudinal survey of young apple plantations in Serbia and the results of pathogen detection and identification using conventional and molecular methods, the plant pathogenic bacterium Erwinia amylovora was found as the causative agent. By increasing the incidence of collar and rootstock blight in young apple trees, E. amylovora is gaining importance as the most destructive disease in apple production. In order to control E. amylovora effectively and apply appropriate control measures, it is necessary to survey the development of lesser-known symptoms caused by this pathogen, which are becoming prevalent in Serbian agroecological conditions.
The effect of cash retention and investment on the operational performance of Brazilian exporting and domestic companies in periods of economic growth and recession

The objective of this paper is to verify what is the effect of cash retention and investment in fixed assets on the operational performance of Brazilian exporting and domestic companies listed in B3, in a period of economic growth and Brazilian economic recession, covering the period from 2005 to 2018. The findings show that, during the period of economic recession, Brazilian exporting companies with higher cash retention and higher investment in fixed assets presented superior operational performance than other companies that adopted different strategies of investment of resources. Still more internationalized exporting companies with higher cash retention and investment in fixed assets performed better than the less internationalized ones. As a major contribution, the research shows that exporting is not enough for superior operational performance, but that diversification must be accompanied by resource application strategies that provide better results, as recommended by the Resource-Based View Theory (VBR).
F EW -S HOT L EARNING WITH W EAK S UPERVISION

Few-shot meta-learning methods aim to learn the common structure shared across a set of tasks to facilitate learning new tasks with small amounts of data. However, provided only a few training examples, many tasks are ambiguous. Such ambiguity can be mitigated with side information in terms of weak labels which is often readily available. In this paper, we propose a Bayesian gradient-based meta-learning algorithm that can incorporate weak labels to reduce task ambiguity and improve performance. Our approach is cast in the framework of amortized variational inference and trained by optimizing a variational lower bound. The proposed method is competitive to state-of-the-art methods and achieves signiﬁcant performance gains in settings where weak labels are available.
RMHP_A_289125 3245..3257

1Madda Walabu University Goba Referral Hospital, School of Health Sciences, Public Health Department, Goba, Bale, Ethiopia; 2Madda Walabu University Goba Referral Hospital, Department of Surgery, Goba, Bale, Ethiopia; 3Madda Walabu University Goba Referral Hospital, Department of Nursing, Goba, Bale, Ethiopia Background: Stethoscopes and non-infrared thermometers are the customary medical equipment used by the physicians on a daily basis, among various patients. With the rise of potential infections in the healthcare facilities and the transmission nature of the current COVID-19 pandemic, consistent and correct disinfections of these devices after each use should not be pardoned. This study, therefore, aimed to assess the level of stethoscope and non-infrared thermometer disinfection practices among physicians involved in direct patient contact during the COVID-19 pandemic. Methods: A web-based cross-sectional survey was conducted among physicians working in Ethiopia to assess their practice of stethoscope and non-infrared thermometer disinfection. The online survey was circulated using an anonymous and self-reporting questionnaire via Google form with a consent form appended to it. The developed Google form link was shared with physicians through their email addresses and social media pages. A descriptive summary was computed and presented by tables and figures. Multivariable logistic regression model was used to identify factors associated stethoscope and non-infrared thermometer after every use. Results: The proportion of stethoscope and non-infrared thermometer disinfections after every use was 13.9% (95% CI: 10.9–17.6) and 20.4% (95% CI: 16.7–24.5), respectively. Taking COVID-19 training (AOR: 2.52; 95% CI: 1.29–4.92) and the availability of stethoscope disinfection materials at the workplace (AOR: 3.03; 95% CI: 1.29–7.10) were significantly increased the odds of stethoscope disinfection after every use. The odds of stethoscope disinfection after every use was significantly decreased for those who reported the use of shared stethoscope (AOR: 0.34; 95% CI: 0.12–0.92). Conclusion: Only a wee share of the respondents reported that they have disinfected their stethoscopes and non-infrared thermometers after every use – possibly jeopardizing both patients and clinicians safety, particularly during the COVID-19 pandemic.
Growth, Oxalate and Vitamin C Content of Red Amaranth (Amaranthus tricolor L.) Treated with Salicylic Acid

Red amaranth (Amaranthus tricolor L.) is one of vegetables that has been widely cultivated in Indonesia. Amaranth foliage contains high nutritive value and is an excellent source of bio-available iron and vitamin A (Funke 2011). It has been reported by Peter et al. (2014) that in fresh leaves of A. cruenthus, β-carotene, iron and zinc content was 5.75±0.04, 8.47±0.05, and 3.18±0.04 mg/100 g, respectively. Amaranth leaves and seeds are good source of protein. According to Andini et al. (2013) the average protein content in leaves of cultivated A. cruentus L. and A. tricolor L. were about 16%. Amaranth is also considered as a drought resistant plant and it can be appraised for future crop that can withstand climate change. However, beside its nutritive contents, amaranth leaves and grain contain oxalate. The presence of oxalate in food decline the availability of calcium and magnesium and for human being it can promote kidney stone development. From analysis of 30 genotypes amaranth’s grain, the average concentration of oxalate was 229 mg/100 g (Gelinas and Seguin 2017). Another report by Vityakon and Standal (1989) showed that total oxalate content was 91 g kg−1 on a dry weight basis in A. gangeticus L. grown in three different soil types and climatic factors. The average content of oxalate in plants is also affected by nitrogen source and the availability of inorganic ions (Libert and Francheschi 1987). Efforts in reducing oxalate content in vegetable are still important to be conducted. It has been suggested that oxalic acid biosynthesis can be derived from glyoxylate/glycolate, ascorbate, and oxaloacetate (Cai et al. 2015). In spinach, the accumulation of oxalate can be regulated by ammonium and nitrate. Under normal condition, the transcription levels of genes that involved in oxalate biosynthesis, such as SoGLO2, SoGLO3, SoOXACs, SoMLS, SoMDH1, SoMDH2, and SoMDH were high and it leads to high oxalate concentration (Cai et al. 2018). According to Kostman et al. (2001) the potential precursor of oxalate is ascorbic acid. Another finding by Truffault et al. (2017) reported that through [14C] ascorbate labelling in tomato, oxalate, threonate as well asoxalyl threonate, were found as the degradation products of ascorbate. The degradation of ascorbate in plants may occur enzymatically through ABSTRACT
Photoactivity and Stability of WO3/BiVO4 Photoanodes: Effects of the Contact Electrolyte and of Ni/Fe Oxyhydroxide Protection

Photoelectrodes with the WO3/BiVO4 heterojunction architecture are among the most efficient semiconductor oxide-based photoanodes for water oxidation. However, because of the different experimental conditions employed in their photoelectrochemical characterization (in particular the nature and concentration of the contact electrolyte and the pH of the solution), a direct and unambiguous comparison of their performance obtained in different laboratories is often quite difficult. In this work, we systematically tested identical WO3/BiVO4 photoanodes in contact with solutions of the most commonly used electrolytes, i.e. Na2SO4 and the potassium phosphate buffer (KPi), at various electrolyte concentration and pH. Furthermore, WO3/BiVO4 photoanodes protected with a Ni/Fe oxyhydroxide oxygen evolution catalyst were also tested under identical conditions. In contact with KPi solutions, both unprotected and protected electrodes produce higher photocurrent than in contact with Na2SO4 solutions, but they proved to .
On the reversed bias-variance tradeoff in deep ensembles

Deep ensembles aggregate predictions of diverse neural networks to improve generalisation and quantify uncertainty. Here, we investigate their behavior when increasing the ensemble members’ parameter size - a practice typically associated with better performance for single models. We show that under practical assumptions in the overparametrized regime far into the double descent curve, not only the ensemble test loss degrades, but common out-of-distribution detection and calibration metrics suffer as well. Rem-iniscent to deep double descent, we observe this phenomenon not only when increasing the single member’s capacity but also as we increase the training budget, suggesting deep ensembles can beneﬁt from early stopping. This sheds light on the success and failure modes of deep ensembles and suggests that averaging ﬁnite width models perform better than the neural tangent kernel limit for these metrics.
Growth and Early Laying Performance of Pullet Chickens Fed Sorghum Based Diets Supplemented with Enzymes

Nigerian Society for Animal Production Nigerian Journal of Animal Production © A study was carried out to evaluate the effect of replacing maize with sorghum and supplementation with enzymes, on the growth and laying performance of laying chickens. Four hundred and fifty 12-weeks old Lohmann Brown pullets were distributed randomly into six dietary treatments with three replicates per treatment, each replicate had 25 birds with uniform group weights at the initial stage of the study. The treatments included maize without enzymes (T1) and sorghum without enzymes (T2) as two controls respectively, while T3, T4, T5, and T6 contained sorghum based diets with phytase, protease, roxazyme G2G, and a combination of protease and roxazyme G2G respectively. The experiment lasted from 12 to 32 weeks of age of birds during which data were collected on growth and early egg laying performance of birds. Data obtained were subjected to analysis of variance, using the completely randomized design (CRD). Significant differences among treatment means were compared using the Tukey test. Significant (p<0.05) differences were noted in final weight (g/bird), weight gain (g/bird), daily weight gain (g/bird), total feed intake (g/bird), daily feed intake (g/bird/day), and feed to gain ratio. Final weight and weight gain were significantly (p<0.05) better for birds in T4 (sorghum + protease) compared to the other treatments, but was similar to T1 (control). At the early laying stage, no definite trend was observed among the egg production traits. However, dietary treatment supplemented with phytase (T3) had the highest numerical values for; weight of first egg (54.28g), number of eggs at peak lay (24.00), hen house egg production 78.84%, and hen day egg production, 81.09%. It was concluded therefore, that sorghum with phytase and protease supplementations can be used in layers' diets for optimum egg production. It is recommended that phytase supplementation at 0.02% with sorghum can be incorporated into the diets of egg type chickens for optimum performance. Introduction Maize has remained the main energy source in compounded diets and constitutes about 50% of poultry ration (Ajaja et al., 2002). According to Etuk (2008), these trends require serious diversification of energy feedstuff for poultry. The fact that feed alone accounts for 70 – 80% of the production inputs in intensive monogastric animal production, makes the utilization of cheaper and alternative feed ingredients expedient. The main aim of using nonconventional feed ingredients is to reduce the cost of production thus making it possible for an average Nigerian to be able to afford animal protein in their meals (Olabanji et al., 2009). Sorghum bicolor (L) Moench is widely grown in the semi-arid and arid savannah regions of Nigeria. Maunder (2002) reported that, sorghum is a traditional crop in much of Africa and Asia, and an introduced and hybridized crop in the western hemisphere. In terms of the nutritive value, cost and availability, sorghum grain is the next alternative to
Cognitive and GABAergic protection by hAPP and hTau coexpression: a model of Non-Demented with Alzheimer’s disease Neuropathology

Alzheimer’s disease comprises amyloid-β (Aβ) and hyperphosphorylated Tau (P-Tau) accumulation, imbalanced neuronal activity, aberrant oscillatory rhythms, and cognitive deficits. Non-Demented with Alzheimer’s disease Neuropathology (NDAN) defines a novel clinical entity with Aβ and Tau pathologies, but preserved cognition. The mechanisms underlying such neuroprotection remain undetermined and animal models are currently unavailable for NDAN. We show that J20/VLW mice, accumulating Aβ and P-Tau, exhibit preserved hippocampal rhythmic activity and cognition, altered in J20 and VLW animals. Furthermore, we show that coexistence with Aβ renders a particular P-Tau signature in hippocampal interneurons. The GABAergic septohippocampal pathway, responsible for hippocampal rhythmic activity, is preserved in J20/VLW mice, in contrast to single mutants. Our data highlight J20/VLW mice as a suitable animal model to understand the mechanisms driving cognitive preservation in NDAN and suggest that a differential P-Tau pattern in hippocampal interneurons prevents GABAergic septohippocampal innervation loss and alterations in local field potentials, avoiding cognitive deficits.
The aerodynamics of the wavy blade under the effect of fluctuated wind flow

In the present study, the influence of the wavy edge blade on aerodynamic characteristics for the flow of blades at Reynolds number (Re) of 8×10 is numerically investigated based on the unsteady wind flow. Aerodynamic characteristics of a (sinusoidal leading edge) wavy NACA0015 aerofoil blade are carried out using ICEM 19.1 and ANSYS fluent. The numerical simulation is conducted then validated by experimental data with steady wind flow. This is conducted by employing the same Reynold's number in the experimental work. While, the unsteady flow was numerically performed at 1 Hz frequncy of wind flow conditions. The main findings from this work show that the wavy blade can behave better in turbulent wind conditions with the maximum lift coefficient of 0.73 compared to 0.621 for the normal blade. However, the findings declare that the wavy blade stalled earlier than the normal one in the unsteady flow case. Similarly, it stalled at 12 angle of attack earlier than the normal one which was stalled at 14 in the steady flow case.
Knee Flexors Maximum Effective Angle Variation after Anterior Cruciate Ligament Reconstruction with Hamstring Graft

Background: During the anterior cruciate ligament reconstruction, the graft is taken from the distal hamstring tendon, which causes morphological and neurological changes in these muscles, particularly on the maximum effective angle of the knee flexors. The present study investigates changes in knee flexor following anterior cruciate ligament reconstruction with a hamstring graft. Methods: Two populations participated in this study, a healthy group and a group that underwent anterior cruciate ligament reconstruction with a hamstring graft. First, the test group underwent two postoperative assessments on an isokinetic device at 3 and 6 months. Next, we compared the test group at 3 and 6 months with the control group to highlight the differences between the knee flexors maximum effective angle. And finally, we have compared the knee flexors maximum effective angle with the moment of maximum force to determine whether these two values are related. Results: The maximum effective angle is decreased regardless of the duration of rehabilitation (ρ= 0.0019, ρ = 0.037). It does not change significantly during rehabilitation (ρ = 0.29). It does not depend on the strength gained during rehabilitation but on a neuromotor change due to the morphological changes caused by surgery. Conclusion: The study results show that anterior cruciate ligament reconstruction with hamstring graft causes a decrease in knee flexor maximum effective angle.
Screening for Ecologically Competent, Nutritional Characteristics and Symbiotically Effective Chickpea Nodulating Mesorhizobium spp. Isolated from Acidic Soils of Ethiopia

Background: Nitrogen fixations are limited in acidic soil due to the sensitivity of legume, rhizobia, and the symbiosis to low pH. However, legumes and their rhizobia show different responses to soil acidity. Objective: The experiment was conducted to screen indigenous Mesorhizobium isolates for their ecological competitiveness and symbiotically effectiveness for enhancing nitrogen fixation in chickpea production. Methodology: A total of 81 genetically diverse indigenous Mesorhizobium spp. were screened for low pH tolerance and their potential to ecological adaptations under in vitro conditions and their symbiotic effectiveness on two chickpea varieties under greenhouse conditions. Results: 62 (77%) strains grew well at low pH 5, and 47 (75.8%) of them were phosphate solubilizers. The species displayed marked differences in their eco-physiological characteristics such as the utilization of different carbon and nitrogen sources, pattern of tolerance to salinity, temperature, Mn2+ and Al3+ toxicity, heavy metals, and inherent resistance to antibiotics. They also displayed significant (p<0.01) differences in their nodulation features (nodule number, nodule dry weight) and yield characters (shoot dry weight) on Natoli and DZ-ck-2011s-2-0042 chickpea varieties. Based on their symbiotic effectiveness (SE), five strains, namely a.15star (ANI95 groups 5C), a.117L2 (ANI95 groups 2D), a.71 (ANI95 groups 4B), a.40L2 (ANI95 groups 8A), and a.200M (ANI95 groups 3A) showed the best performance on both varieties, even out-performed over the commercially available local strain Cp41 and tolerance to different in vitro ecological conditions. Conclusion: Ethiopian acidic soils harbored symbiotically effective, ecologically competent, and phosphate solubilizing Mesorhizobium species. Thus, these strains could be recommended as prospective commercial inoculants provided they can be tested in field trials in acidic soils.
BULLYING BEYOND THE CLASSROOM: GRADE AND GENDER DIFFERENCES IN CYBERBULLYING IN GRADES FOUR THROUGH EIGHT

The present study was conducted to investigate the grade and gender differences in cyberbullying in students from grades four through eight. It was predicted that females would experience cyberbullying and engage in cyberbullying more often than their male counterparts. It was also predicted that as the students progressed from grade four through to grade eight, the frequency of cyberbullying would increase. Data from a previous study in a large Southwestern Ontario school board was analyzed to investigate these hypotheses. Results indicated that cyberbullying was more frequent for female students than male students and also for the older students compared to the younger students. The results are discussed in terms of the relevance to previous findings. Implications for prevention programs in schools and suggestions for future research are discussed.
Reuse of by-products material as a conditioner to improve thickening and dewatering of sludge

Although sludge conditioning using chemicals has been employed widely to improve the thickening and dewatering processes and considered as is a good alternative for process improvement, however, its cost is high. Therefore, it is important to find effective and cheap conditioners. Large quantities of cement kiln dust (CKD) – from cement factories, and fly ash (FA) – from power plants, are promising conditioning agents. Accordingly, the experimental work presented in this study was designed to investigate the effect of using these by-products and their mixture on the thickening and dewatering performance of different types of sewage and drinking water sludge. The results show that the mixture of the CKD and FA had the higher effect and it increased the settling velocity, hydraulic loading rate and solid loading rate of all tested sludge types. The percent increase ranged between 67% and 225%, the dewaterability of the treated and untreated sludge was investigated by gravitational settling test, specific resistance to filtration with indicators for drying beds – solid loading rate and dewatering time and indicators of mechanical dewatering yield. Dewaterability tests show that using the CKD is more effective than the FA or the mixture for dewatering and it could decrease the drying time by values ranged from 37% to 87%.