Miracle-dz/UniFAR-FTUs huggingface dataset:
Screening and Interventions for Overweight and Obesity in Adults

This report may be used, in whole or in part, as the basis for development of clinical practice guidelines and other quality enhancement tools, or a basis for reimbursement and coverage policies. AHRQ or U.S. Department of Health and Human Services endorsement of such derivative products may not be stated or implied. AHRQ is the lead Federal agency charged with supporting research designed to improve the quality of health care, reduce its cost, address patient safety and medical errors, and broaden access to essential services. AHRQ sponsors and conducts research that provides evidence-based information on health care outcomes; quality; and cost, use, and access. The information helps health care decisionmakers—patients and clinicians, health system leaders, and policymakers— make more informed decisions and improve the quality of health care services. (USPSTF) and input from Federal partners and primary care specialty societies, the Evidence-based Practice Center at the Oregon Health Sciences University systematically review the evidence of the effectiveness of a wide range of clinical preventive services, including screening, counseling, and chemoprevention, in the primary care setting. The SERs—comprehensive reviews of the scientific evidence on the effectiveness of particular clinical preventive services—serve as the foundation for the recommendations of the USPSTF, which provide age-and risk-factor-specific recommendations for the delivery of these services in the primary care setting. Details of the process of identifying and evaluating relevant scientific evidence are described in the " Methods " section of each SER. The SERs document the evidence regarding the benefits, limitations, and cost-effectiveness of a broad range of clinical preventive services and will help further awareness, delivery, and coverage of preventive care as an integral part of quality primary health care. AHRQ also disseminates the SERs on the AHRQ Web site and disseminates summaries of the evidence (summaries of the SERs) and recommendations of the USPSTF in print and on the Web. These are available through the AHRQ Web site and through the National Guideline Clearinghouse * The USPSTF is an independent panel of experts in primary care and prevention first convened by the U.S. Public Health Service in 1984. The USPSTF systematically reviews the evidence on the effectiveness of providing clinical preventive services-including screening, counseling, and chemoprevention-in the primary care setting. AHRQ convened the USPSTF in November 1998 to update existing Task Force recommendations and to address new topics. The investigators deeply appreciate the contributions of Loraine Monroe at RTI, for superior secretarial assistance. …
Adolescent engagement during assent for exome sequencing

ABSTRACT Background: Research focused on describing the content of informed consent interactions has shed little light on how to best to encourage, support, and nurture adolescent participation in genomic sequencing. Research addressing adolescents' comprehension and agency is needed because sequencing may have significant implications for an adolescent's own future health status, as well as for other members of the adolescent's family. This article explores adolescent participation and decision making during informed consent for exome sequencing. Methods: Investigators recruited 25 adolescents with unexplained hearing loss, cardiac arrhythmias, mitochondrial disease, or neurodevelopmental disorders from an urban teaching and research hospital for participation in a research project offering whole exome sequencing. Twenty-five adolescents ages 12–19 years and their parents completed informed consent sessions with study clinicians lasting up to 90 minutes. Sessions were digitally recorded, transcribed, and analyzed using grounded theory's “constant comparative” method. Results: Adolescent participants were briefly active when asked direct questions. Otherwise, they stayed mostly quiet. Parents functioned as protectors and information holders. Clinicians used proscriptive language to direct families to consider adolescents' preferences, to balance the interests of multiple caregivers, and to give families time to consider their options before making decisions. In two cases of significant family disagreement, providers maintained a nondirective stance toward all parties and excused themselves from the intense discussion by deferring decisions to a later date. Conclusions: Conventional approaches to informed consent may be insufficient to the risks, benefits, and possibilities offered by genomic sequencing. Rather than target autonomy, enhancing the agency of adolescents in decision making may more appropriately address their needs so that all stakeholders provide input and are respected throughout the informed consent process.
PATTERNS AND PREVALENCE OF MUCOCELES AMONG PATIENTS REFERRED FOR CRANIO-FACIAL COMPUTED TOMOGRAPHY IN PORT HARCOURT METROPOLIS

Background: Mucocele is rare benign, expansile pseudocystic pathology of the nasal and paranasal sinuses. This study aimed at evaluating the patterns and prevalence of mucoceles among patients referred for cranio-facial computed tomography in Port Harcourt metropolis. Materials and Methods: We performed a retrospective review of all the radiological reports of patients that underwent cranio-facial CT scan(n =1,443) between January, 2014 and August, 2017 using data capture sheet. The prevalence, and demographic variables were evaluated. The obtained data were analyzed using descriptive statistics. Results: Out of the 1,443 subject records included in this study, only 2.6% (n = 38) had mucocele. The highest percent of mucocele was seen among subjects of age group 16-30years 1.11% (n = 16) followed by 31-45 years 0.77% (n = 11). Males had the highest percentage of mucocele 1.5% (n = 22) when compared to the female population 1.1% (n = 16). Nasal obstruction was the highest presenting symptom 32.69% (n = 17) and the least was toothache 1.92% (n = 1). Paranasal sinuses was highly involved 65.43% (n = 53) and the least was nasal involvement 12.35% (n = 10). Frontal sinus was the most common affected sinus 23.46% (n = 19) and the least was sphenoid sinus 6.17% (n = 5). Conclusion: The incidence of mucocele pathology was quite low in Port Harcourt. Young adults were more commonly affected by mucocele pathology with male preponderance. Frontal sinuses were the most affected paranasal sinus in this study.
Optimising Fusion’s Contribution to Economically Efficient Climate Change Mitigation

The context within which fusion development planning is undertaken is changing. Recent publications by the Stern Review (by the former Vice-President and Chief Economist of the World Bank) and by the Intergovernmental Panel on Climate Change have removed most of the residual uncertainties about the cost, reality, causation and pace of climate change. Governmental decisions, and demonstrations of public support, have displayed increasing commitment to mitigating climate-changing emissions. The ITER Treaty and the Broader Approach Agreement have removed much uncertainty relating to the near-term steps of fusion development. Concerns over energy security and diversity of supply have markedly increased. Thus, it has become reasonable to plan on the assumption that in twenty years time ITER and IFMIF will have been successful and the world will be eager for clean, secure energy supplies. Previously published ‘fast track’ scenario studies all assumed a sequential model of fusion development, severely constrained by funding. The present paper explores the economic justification for relaxing these assumptions, and the resulting potential for more rapid, but cost-effective, fusion deployment. This includes the acceptability of reduced targets for the internal cost performance of the first generation of power plants, and overlapping of development stages.
Biosynthesis of Copper Oxide Nanoparticles Using Ailanthus Altissima Leaf Extract and Antibacterial Activity

An eco-friendly green route for synthesis copper oxide nanoparticles (CuONPs) by Ailanthus altissima leaf aqueous extract was reported. The synthesized copper oxide nanoparticles were characterized in terms morphology, crystalline nature, structural and antibacterial activity with UV-vis, SEM, TEM, FT-IR analysis tools. The synthesized copper oxide nanoparticles were well crystalline in nature with particle shape spherical and average particle size 20 nm. The antimicrobial activity of CuONPs was determined by disk diffusion method against some selected species of bacteria, demonstrated a significant inhibitory activity against S. aureus followed by E. coli. In view of promising activity, the CuONPs could possibly be employed as antibacterial agent.
THE EFFECT OF GARDEN CRESS SEEDS ADDITION ON RHEOLOGICAL PROPERTIES OF WHEAT FLOUR AND CHOCOLATE FLAVORED CUPCAKE

TECHNOLOGICAL, medicinal and nutritional importance of garden cress seed powder was the most vital aspect ofthis study. This search was designed to study the effect of the addition of garden cress seeds powder (GCSP), with the replacement ratio of 5, 10 and 15% of wheat flour, on the rheological properties of wheat flour and specific volume, texture analysis, stalling and sensory properties of chocolate flavored cupcake processing. GCSP is a rich source of protein, carbohydrates, dietary fiber, fat, ash, potassium, phosphorus, magnesium, iron, polyphenols and flavonoids. GCSP had good functional properties. The water absorption (WA) percentages increased clearly with the addition of GCSP being 59, 62, 66 and 72% for control, 5, 10 and 15% treated flours, respectively. The control sample had the maximum mixing tolerance index (MTI). arrival time (AT), dough development time (DDT), departure time (DT) and stability of dough (SD) was increased with the increase of GCSP. The wheat flour containing 5% GCSP had the highest resistance to extension (R50), maximum resistance (MR) and ratio number (R50/E). The extensibility (E) and dough strength (DS) were decreased by increasing the level of GCSP addition. The replacement of wheat flour with 5, 10 and 15% increased significantly (p≤0.05) the weight, volume and specific volume of the resulted cupcakes with GCSP. Cupcake containing 15% of GCSP had the lowest hardness 1, hardness 2, springiness, gumminess and chewiness followed by that containing 10% of GCSP except for springiness. Cupcake containing 15 % of GCSP had the lowest decrease percent of alkaline water retention capacity (AWRC) during storage periods being 1.67, 1.90 and 2.79 at 2, 4 and 6 days of storage, respectively, followed by cupcake containing 10%, 5% GCSP and finally the control sample. Cupcakes containing GCSP were more acceptable and fresher than control samples. Thus, the addition of GCSP to wheat flour improved rheological properties and also improved cupcake quality.
Development of Eggless Cake Using Grass Carp (Ctenopharyngodon idella) Protein Concentrate and its Quality Attributes

Original Research | Volume 6 | Number 1| 21 Copyright 2020 by Xia W. This is an open-access article distributed under Creative Commons Attribution 4.0 International License (CC BY 4.0), which allows to copy, redistribute, remix, transform, and reproduce in any medium or format, even commercially, provided the original work is properly cited. cc Purpose The purpose of this study was to explain the quality of 5%, 8%, and 12% of grass carp fish protein concentrate (FPC) supplemented cake. Proximate composition, batter rheology, texture analysis, baking loss, color evaluations, and sensory analysis were performed to explain the quality. Materials and Methods Grass carp fish of about 40 cm length and 4 kg weight, sugar, flour, vegetable oil, baking soda, and baking powder were bought from the local market in Wuxi, Jiangsu, China, while vanilla essence, hydroxy propyl methyl cellulose (HPMC) and glycerol monostearate (GMS) were obtained from Jiangnan University Food Science Laboratory. Results and Discussion An impressive increment in the crude protein (9.10-16.75%), crude fat (10.39-12.30%), and ash (1.22-1.35%) were noticed for FPC supplemented cake. With the increase in FPC quantity, the viscosity of batters lightly decreased (106.41-106.00) and specific gravity increased from 0.9619-1.0073. A non-uniform change was observed in hardness but gumminess and chewiness were increased while cohesiveness and elasticity were found to be decreased. Baking loss (CL) was increased (10.28-11.13) with an increasing level of FPC. The brightness (L*), yellowness (b*) and redness (a*) of FPC 5%, 8%, and 12% fortified cake was recorded as 59.56-57.15, 29.23-31.24, and 10.85-12.75, respectively. Conclusion The cakes prepared with 12% FPC have high nutritional value but showed low sensory attributes due to its dark color and slight fishy flavor while cakes prepared with 8% FPC supplementation revealed the best results for all sensory attributes. In short, a protein-enriched with acceptable quality and sensory attributes, the cake could be prepared by 8% FPC incorporation and eventually could assure effective utilization of fish.
EFFECT OF INDUCTION CHEMOTHERAPY ON VITAMIN D LEVEL IN CHILDREN WITH ACUTE LEUKEMIA

Background: Subnormal level of vitamin D are associated with the higher frequency of cancer and correlated with inferior prognosis in some cancers; no data exist for acute leukemia. Aim of the work: To clarify the relationship between serum vitamin D levels and acute leukemia in children. Materials and Methods: Vitamin D level was measured in sixty-six pediatric patients who are newly diagnosed with acute leukemia in Central Child Teaching Hospital during a period between March 5 th to August 30 th , 2017 and normal 50 children were considered as the control group. Information on the patients were obtained from the medical files of the patients. Patients were classified on a random base as active patients group how the received daily requirement of vitamin D during induction chemotherapy period and passive patients’ group who were treated with chemotherapy only. Vitamin D level was reassessed at the time of remission. Results: The serum vitamin D level in children with acute leukemia was below normal ranges; at the time of diagnosis, the mean of serum level was 13 ng/dl, while in the control group was 21 ng/dl. There was a statistical difference between the patient's group and the control group (p-value 0.001). At the time of remission, serum vitamin D level decreased to 11.8 ng/dl in the passive patients’ group and increased in active patients group to 17.1 ng/dl. Conclusion: vitamin D level was low in a majority of pediatric patients with acute leukemia, and it was further reduced after induction-remission in patients without vitamin D replacement. INTRODUCTION: It is well known that vitamin D is involved in many roles and integrated into the function of many tissues nowadays. This was justified by the discovery of the receptors for vitamin D in most of the body tissues. These receptors are labeled as vitamin D receptors (VDR) 1, 2 . QUICK RESPONSE CODE DOI: 10.13040/IJPSR.0975-8232.11(3). 1367-72 The article can be accessed online on www.ijpsr. com DOI link: http://dx.doi. org/10.13040/IJPSR.0975-8232.11(3). 1367-72 To date, there are two forms of vitamin D; Calcitriol (D3) which is a derivative of 7dehydrocholesterol by the effect ultraviolet light, and Ergocalciferol (D2) which is derived from the plant sterol ergosterol. The VDR is a transcription factor that binds to DNA, which in turn, called vitamin D response elements (VDREs) 3 . Normal mineral regulation in the bones is maintained by the body’s ability for regulating 1, 25 (OH) 2D secretion 4 . Twenty-five years ago, scientists wrote about the immune response modulation of 1, 25 (OH) 2D 5 . It inhibits the adaptive immune response, suppresses proliferation, immunoglobulin production and delays B cell
A Simple Approach for Non-stationary Linear Bandits

This paper investigates the problem of non-stationary linear bandits, where the unknown regression parameter is evolving over time. Existing studies develop various algorithms and show that they enjoy an $\widetilde{\mathcal{O}}(T^{2/3}P_T^{1/3})$ dynamic regret, where $T$ is the time horizon and $P_T$ is the path-length that measures the fluctuation of the evolving unknown parameter. In this paper, we discover that a serious technical flaw makes their results ungrounded, and then present a fix, which gives an $\widetilde{\mathcal{O}}(T^{3/4}P_T^{1/4})$ dynamic regret without modifying original algorithms. Furthermore, we demonstrate that instead of using sophisticated mechanisms, such as sliding window or weighted penalty, a simple restarted strategy is sufficient to attain the same regret guarantee. Specifically, we design an UCB-type algorithm to balance exploitation and exploration, and restart it periodically to handle the drift of unknown parameters. Our approach enjoys an $\widetilde{\mathcal{O}}(T^{3/4}P_T^{1/4})$ dynamic regret. Note that to achieve this bound, the algorithm requires an oracle knowledge of the path-length $P_T$. Combining the bandits-over-bandits mechanism by treating our algorithm as the base learner, we can further achieve the same regret bound in a parameter-free way. Empirical studies also validate the effectiveness of our approach.
Progress in Research on Nonalcoholic Fatty Liver and Gestational Diabetes

Although there is ample evidence that non-alcoholic fatty liver disease (NAFLD) is associated with impaired glucose homeostasis in the body, the clinical significance of NAFLD in pregnant women has not been established. Current studies have shown that women with NAFLD during early pregnancy have a significantly increased incidence of gestational diabetes mellitus (GDM) during pregnancy; whereas women with a history of GDM have a significantly increased probability of developing NAFLD in the future. Both may be a manifestation of an etiology in both systems, reflecting the impaired glucose homeostasis and the continuity of insulin resistance. For women with NAFLD found in early pregnancy, it is recommended to closely monitor blood glucose during pregnancy, and if necessary, early intervention to strengthen prenatal and postnatal care. The presence of GDM at a young age in women may be an early marker that helps to screen out women at higher risk of developing a disease before significant metabolic disease, and is of great significance in reducing associated morbidity and mortality.
Histological and Immunohistochemical Studies on the Role of Stem Cells on the Burned Skin of Adult Male Albino Rats

Background: Mesenchymal stem cells have delivered new approaches to the management of burn healing in severe skin injuries. Aim of the work: To evaluate the effect of bone marrow-derived mesenchymal stem cells (BMSCs) on healing of induced deep 2nd degree skin burns in albino rats. Methodology: 55 male albino rats weighed 200gm were divided into 5 groups, 5 animals in group I (control) and group II (burn model), 15 animals in group III (untreated), group IV and group V (MSCs treated). Groups III, IV and V were subdivided into 3 subgroups that were sacrificed after 7, 14 and 21 days respectively. Deep 2nd degree burn wounds were induced on a 4 cm2 area on the back of rats in groups II, III, IV and V by brass probes stabilized at 88–90°C and contacted to the shaved dorsal skin of rats for 20 seconds without exerting any external pressure. Mesenchymal stem cells were isolated from the bone marrow of 5 young rats, weighed 100gm then intra-dermally and intraperitoneally injected. Results: By the end of the third week, the wounds of BMSCs-treated groups showed full regeneration of epidermis, re-organization of collagen and decrease in VEGF immunopositive cells. Delayed wound healing was seen in 20% of systemically treated rats. Significant increase in the mean area percent of collagen fibers was detected in topically treated group. Conclusion: Both methods of BMSCs injection were effective in healing of full thickness skin wound but topical method was more effective.
Electromagnetic (EM) Design of an Annular Coupled Accelerating Structure for the Advanced Compact Carbon Ion Linac (ACCIL)

Radiotherapy with carbon ion beams has become a popular topic throughout the world, due to its desirable features including sharp Bragg peak and greater radio-biological effectiveness. the Argonne National Laboratory recently embarks on developing the Advanced Compact Carbon Ion Linac, a linear accelerator designed for performing carbon therapy. The work presented here focuses on the coupled cavity linac (CCL) of ACCIL, which is crucial for its compactness. In this project, we designed the CCL based on the annular coupled structure and successfully optimized the cavity frequency and field distribution. We also studied the sensitivity of the cavity to machining errors and the tuning capabilities of tuners installed on the accelerating cells. Lastly, we applied the coupled resonator model to describe our accelerating cavity.
Transparency and persuasion: The impact of preliminary information on informational lobbying

Policy makers value the information they receive from special interest groups but have little control over the type of information these groups choose to obtain. I build a model of informational lobbying in which a policy maker can choose what type of preliminary evidence to gather before a lobbyist attempts to persuade her. When the policy maker can commit to limiting the precision of her preliminary evidence, she benefits from keeping that evidence private as it can force the lobbyist to reveal more information. When that commitment is not possible, she would prefer her preliminary evidence to be publicly available. I characterise the policy maker’s optimal choice of preliminary information and identify when privacy is beneficial.
Investigation of an Extended Climate-Economy Model A thesis presented in partial fulfillment of the MATH 4 P 06 course

We aim to investigate the intricacies of a robust climate-economy, stock-flow consistent model, and the effects of rising temperatures on this system. Building upon the prior research of Bovari et al. (2017) [1], we extend their macroeconomic module by adding inventory dynamics, explicit consumption, and active public and banking sectors. Following similar numerical simulation techniques as those described in [1], we analyze the dynamical behaviour of our model in the case of the United States. We observe that our results do not display the rich behaviour of previous Keen-based literature, instead displaying an economic collapse in the long term. We conclude by identifying future research avenues, and proposing improvements to our current model. Department of Mathematics and Statistics Under the supervision of Dr. Matheus Grasselli and Dr. Ben Bolker McMaster University April 2019
Comparative Analysis of Search Engine Usage, Relevance and Effectiveness among Final Year Undergraduate Students

— Globally, final year undergraduate students in universities carry out project reports as part of requirements for graduation. However, for meaningful project to be done in this era of Information and Communication Technology, there is need for them to make use of search engines which is synonymous today with Google in some clime. This paper examines the use of Web search engines by final year students to support learning and research in a Nigerian University. The frequency of usage of search engines, their level of satisfaction with search results, the effectiveness of the search engines as well as the relevance of results obtained by various search engines were investigated. The results showed that Google search engine was adjudged the best with highest frequency of usage and result retrieval outcome. Result from chi square test indicates that there is no significant relationship between gender, schools and relevance of results returned by the search engines