Miracle-dz/UniFAR-FTUs huggingface dataset:
An Anchor-based Relative Position Embedding Method for Cross-Modal Tasks

Position Embedding (PE) is essential for transformer to capture the sequence ordering of input tokens. Despite its general effectiveness verified in Natural Language Processing (NLP) and Computer Vision (CV), its application in cross-modal tasks remains unexplored and suffers from two challenges: 1) the input text tokens and image patches are not aligned, 2) the encoding space of each modality is different, making it unavailable for feature comparison. In this paper, we propose a unified position embedding method for these problems, called AnChor-basEd Relative Position Embedding (ACE-RPE), in which we first introduce an anchor locating mechanism to bridge the semantic gap and locate anchors from different modalities. Then we conduct the distance calculation of each text token and image patch by computing their shortest paths from the located anchors. Last, we embed the anchor-based distance to guide the computation of cross-attention. In this way, it calculates cross-modal relative position embedding for cross-modal transformer. Benefiting from ACE-RPE, our method obtains new SOTA results on a wide range of benchmarks, such as Image-Text Retrieval on MS-COCO and Flickr30K, Visual Entailment on SNLI-VE, Visual Reasoning on NLVR2 and Weakly-supervised Visual Grounding on RefCOCO+.
Error Growth in the Numerical Integration of Periodic Orbits, with Application to Hamiltonian and Reversible Systems

We analyze in detail the growth with time (of the coefficients of the asymptotic expansion) of the error in the numerical integration with one-step methods of periodic solutions of systems of ordinary differential equations. Variable stepsizes are allowed. We successively consider "general," Hamiltonian, and reversible problems. For Hamiltonian and reversible systems and under fairly general hypotheses on the orbit being integrated, numerical methods with relevant geometric properties (symplecticness, energy-conservation, reversibility) are proved to have better error growth than "general" methods.
A proof that convection in a porous vertical slab is stable

One of the motivations for study of convection in a porous medium comes from geophysics (see, for example, Elder 1966). Another stems from the fact that convection in a porous medium is often very similar to convection in a viscous fluid, yet the governing equations are of a lower order and so more amenable to study. The viscous-fluid analogue of the problem studied in this paper is of interest in connexion with building insulation involving an unventilated air gap. In that case (see comments of Gill & Davey 1969, 3 7) the equilibrium situation is unstable if, for a given temperature difference across the gap, the width of the gap is above a certain value. Then a cellular motion occurs which will increase the heat transfer considerably. It is shown below, however, that if the gap is filled with a porous medium (fibre glass is often used in the building industry), the corresponding equilibrium situation is always stable. Consider the natural convection of a fluid of kinematic viscosity v, density p and specific heat c which saturates a vertical slab of a porous medium ofpermeability k and thickness L . The slab is assumed to have infinite height. Suppose the convection is induced by holding the vertical boundaries of the slab at different temperatures, the difference being AT. Then the motion is governed by a single parameter, the Rayleigh number A given by
Teachers’ authentic strategies to support student motivation

Introduction Most theories of motivation have largely developed from the work of scholars rather than the perspectives of teachers. This means that although researchers have many recommendations to guide the way teachers motivate students, there is little understanding of what teachers naturally do to support student motivation. The purpose of this study was to prioritize teachers’ perspectives by asking them, separate from theory, what they do to motivate students. Methods Forty-two practicing teachers completed an open-ended online survey in which they described their personal strategies for motivating students. We used thematic analysis to identify codes and themes from practicing teachers’ responses in a qualitative descriptive design. Results We identified 36 discrete codes that gave rise to nine themes: relevance, interest, relationships, effort, safe environment, goals, student self-regulated learning, delivery, and rewards. Member checks were completed to provide evidence of confidence in the results. Discussion All of the strategies that teachers described align with recommendations motivation researchers would make with the exception of rewards, which, from a research perspective, are often discouraged. We discuss the results in light of motivation design principles and their relevance to partnering with teachers as a ubiquitous influence on student motivation.
Spurious solutions of numerical methods for initial value problems

It is well known that some numerical methods for initial value problems admit spurious limit sets. Here the existence and behaviour of spurious solutions of Runge-Kutta, linear multistep and predictor-corrector methods are studied in the limit as the step-size h→0. In particular, it is shown that for ordinary differential equations defined by globally Lipschitz vector fields, spurious fixed points and period 2 solutions cannot exist for h arbitrarily small, whilst for locally Lipschitz vector fields, spurious solutions may exist for h arbitrarily small, but must become unbounded as h→0. The existence of spurious solutions is also studied for vector fields merely assumed to be continuous, and an example is given, showing that in this case spurious solutions may remain bounded as h→0
The clinical relevance of anti-glutamic acid decarboxylase antibodies in children with encephalitis/encephalopathy

Anti-glutamic acid decarboxylase (anti-GAD) antibodies are associated with different types of syndromes. However, few studies have investigated the correlation between anti-GAD antibody titers with clinical severity and outcomes in children with encephalitis/encephalopathy. In this single-center retrospective cohort study, we consecutively enrolled hospitalized children who had encephalitis and/or encephalopathy with positive anti-GAD antibodies in serum and/or cerebrospinal fluid (CSF) from February 2010 to October 2021. Thirty-seven patients were included and divided into high-titer and low-titer groups. The patients with high anti-GAD antibody titers were associated with initial symptoms of language difficulty and ataxia. The level of titers was not associated with severity or outcomes. Anti-GAD antibody titers decreased after immunotherapy, however, the clinical response to immunotherapy was variable. A transient elevation in anti-GAD antibody titers during immunotherapy was noted. Further studies are warranted to investigate the role of anti-GAD antibodies in the pathogenesis and immune mechanisms of encephalitis/encephalopathy.
The invisible burden of managing COVID-19 for Australian women: Cognitive labor and public health information

Providing accurate and timely public health information is an ongoing challenge for public health officials. The COVID-19 pandemic has exacerbated such challenges and presented unique difficulties in providing public health information, through the parallel rise of an “infodemic” of mis/dis-information. Understanding why individuals select, use and change their public health information seeking behaviors around COVID-19, and the relationship of these decisions relative to participant characteristics, is therefore an important step in understanding and responding to infodemics. This study used a qualitative survey (n = 255) and free-text qualitative questions to ask (1) Why participants use an information source, (2) How participants used an information source, and (3) How information seeking behavior has changed since the COVID-19 pandemic. Participants were primarily women, born in Australia, with de-facto/married relationships, without children at home, with university/college qualifications, and employed full-time or unemployed/retired. Most participants identified “easiness” and “immediacy” as reasons why they chose and used information, with sources primarily used for planning, communication, and decision making. A minority of participants changed their information seeking behavior since the COVID-19 pandemic. Those who did change, desired more immediate and accurate information. Emergent themes of care and anxiety were also noted, raising questions around the impact of mental load and cognitive labor in some female populations. Women may be suffering from increased cognitive labor and a gendering of public health information seeking behavior in the context of COVID-19. The impact of these attributes on women requires greater empirical research and consideration amongst front line practitioners and public health professionals.
Identification of Baihesi aluminous A-type granite: Magmatic response to the onset of Cretaceous extension in eastern Jiangnan Massif, South China

The Cretaceous lithospheric extension in South China is very distinct and expressed by systematic extension-related geological records which are concentrated in the coastal terrane, Shi-Hang Rift, and Jiangnan Massif. The Cretaceous extension in the coastal terrane and Shi-Hang Rift began almost simultaneously during 145–140 Ma, while there is a lack of reliable magmatic indication for tectonic extension in the Jiangnan Massif during 145–140 Ma. This paper reports a newly discovered Baihesi granite with a concordant age of 142.52 ± 0.57 Ma (MSWD = 1.2) on the southeast margin of the eastern Jiangnan Massif with evidence from petrology, geochronology, petrochemistry and Hf isotopes. The Baihesi granite is a monzogranite and classified as a peraluminous, high-K calc-alkaline series. The trace element compositions are characterized by relatively flat rare earth element patterns; strong depletion of Eu; slightly enriched light rare earth elements; enrichment of Cs, Rb, Th, U, and Pb; and depletion of Ba, Sr, P, and Ti. Combined with other petrochemistry characteristics, such as high SiO2 content, high differentiation index, low Zr/Hf and Nb/Ta ratios, low ratio between light and heavy REEs, low P2O5 content, and high zirconium saturation temperature, Baihesi granite is proven to be highly evolved aluminous A-type granite. The ε Hf(t) values of Baihesi granite range from −5.57 to −2.37, with two-stage model ages (TDM2) ranging from 1,551 to 1,345 Ma, suggesting a similar source to Neoproterozoic arc-related magmatic rocks in the Shuangqiaoshan Group. We argue that Baihesi granite has originated mainly from partial melting of a reworked juvenile crust related to Neoproterozoic arc-related magmatism in the Jiangnan Massif, which was controlled by subduction along the South China active continental margin. Furthermore, we constrain the onset of Cretaceous extension in the eastern Jiangnan Massif to be 145–140 Ma and highlight the Early Cretaceous reactivation of the northeastern Jiangxi Province fault zone and the structural inheritance in intraplate tectonics.
What I missed from my online therapist: A survey-based qualitative investigation of patient experiences of therapist contact in guided internet interventions

Background The effectiveness of internet-delivered cognitive behavioral therapy (ICBT) in alleviating symptoms of psychological disorders has been demonstrated across qualitative and quantitative studies. Generally, guided ICBT is considered more effective than unguided ICBT. Yet, what therapist contact and guidance specifically add to the treatment is less clear. There is a need for more knowledge about how patients experience the relationship with their therapist in guided ICBT. The aim of the study was to explore what patients missed in the contact with their therapist in guided ICBT in routine care. Methods The study used a qualitative design to explore patients´ experiences of the therapist contact in guided ICBT for social anxiety disorder, panic disorder and major depressive disorder. Following treatment, 579 patients received a survey with the open-ended question “What did you miss in the contact with your therapist? ” The responses were explored thematically using qualitative content analysis. Results A total of 608 unique responses were provided. Of these, 219 responses gave voice to some degree of perceived lack or limitation in their interaction with the therapist or the treatment in general. The analysis yielded three main categories: The first theme, Therapist-ascribed shortcomings, concerned experiences of something missing or lacking in the contact with the ICBT therapist. More specifically, the patients expressed a need for more emotionally attuned and tailored interaction. The second theme was Program obstacles, encompassing expressed wishes for increased therapist responsivity and more contact face-to-face. Self-attributed limitations, the third category, concerned patient experiences of barriers to treatment engagement as originating in themselves. Conclusion This study sheds light on what patients receiving guided ICBT in routine care missed in the contact with their therapist. The patients who expressed that something was missing in the contact with their therapist constituted a small part of the responses in the sample, even after being directly asked. The themes that emerged point to significant experiences of being inadequately related and responded to, both with potential adverse consequences for the treatment. These findings give new insights to the role of the guidance in ICBT and have implications for the training and supervision of guided ICBT therapists.
Efficacy of different intensities of percutaneous electrolysis for musculoskeletal pain: A systematic review and meta-analysis

Objective A meta-analysis of randomized controlled trials (RCTs) was conducted to determine the effect of ultrasound-guided percutaneous electrolysis (PE) alone or as an adjunct to other interventions on pain intensity generated by musculoskeletal disorders, depending on the intensity of the technique. Data sources PUBMED, EMBASE, Cochrane Library, Web of Science, SCOPUS, Health Medical Collection, and CINALH from inception to September 2022 were searched to identify documents. Study selection Publications investigating the effect of ultrasound-guided PE in musculoskeletal pain. Data extraction Data were extracted into predesigned data extraction and tables. Risk of bias was evaluated with the Cochrane Risk of Bias Tool (Rob 2.0). Thirteen articles met inclusion criteria. Data analysis Random-effects meta-analysis models were used to quantify the difference in pain between the PE and control groups. Data synthesis A significant reduction in pain was found in favor of low- (−1.89; 95% CI: −2.69; −1.10; p < 0.001) and high-intensity PE (−0.74; 95% CI: −1.36; −0.11; p: 0.02) compared to control group. Low-intensity PE showed significant reduction in pain in the short (−1.73; 95% CI: −3.13; −0.34; p < 0.02) and long term (−2.10; 95% CI: −2.93; −1.28; p = 0.005), with large effect sizes compared to control group. High-intensity PE only showed significant lower pain than control group in the long term (−0.92; 95% CI: −1.78; −0.07; p < 0.03), with a small effect size, but not in the short term. Conclusion We found small evidence suggesting that low-intensity PE could be more effective for musculoskeletal pain reduction than high-intensity PE. Nevertheless, scientific evidence on this subject is still scarce and studies comparing the two modalities are warranted. Systematic review registration www.crd. york.ac. uk/prospero, identifier CRD42022366935.
Changes in social interaction, social relatedness, and friendships in Education Outside the Classroom: A social network analysis

Introduction Social interaction is associated with many effects on the psychological level of children such as mental health, self-esteem, and executive functions. Education Outside the Classroom (EOtC) describes regular curricular classes/lessons outside the school building, often in natural green and blue environments. Applied as a long-term school concept, EOtC has the potential to enable and promote social interaction. However, empirical studies on this topic have been somewhat scant. Methods One class in EOtC (N = 24) and one comparison class (N = 26) were examined in this study to explore those effects. Statistical Actor-Oriented Models and Exponential Random Graph Models were used to investigate whether there are differences between EOtC and comparison class regarding changes over time in social interaction parameters; whether a co-evolution between social interaction during lessons and breaks and attendant social relatedness and friendships exists; whether students of the same gender or place of residence interact particularly often (homophily). Results Besides inconsistent changes in social interaction parameters, no co-evolutional associations between social interaction and social relatedness and friendships could be determined, but grouping was evident in EOtC. Both classes showed pronounced gender homophily, which in the case of EOtC class contributes to a fragmentation of the network over time. Discussion The observed effects in EOtC could be due to previously observed tendencies of social exclusion as a result of a high degree of freedom of choices. It therefore seems essential that in future studies not only the quality of the study design and instruments should be included in the interpretation – rather, the underlying methodological-didactic concept should also be evaluated in detail. At least in Germany, it seems that there is still potential for developing holistic concepts with regards to EOtC in order to maximize the return on the primarily organizational investment of implementing EOtC in natural environments.
Role of immediate early genes in the development of salivary gland organoids in polyisocyanopeptide hydrogels

Human salivary gland organoids have opened tremendous possibilities for regenerative medicine in patients undergoing radiotherapy for the treatment of head and neck cancer. However, their clinical translation is greatly limited by the current use of Matrigel for organoid derivation and expansion. Here, we envisage that the use of a fully, synthetic hydrogel based on the oligo (-ethylene glycol) functionalized polymer polyisocyanopeptides (PICs) can provide an environment suitable for the generation and expansion of salivary gland organoids (SGOs) after optimization of PIC polymer properties. We demonstrate that PIC hydrogels decorated with the cell-binding peptide RGD allow SGO formation from salivary gland (SG)-derived stem cells. This self-renewal potential is preserved for only 4 passages. It was found that SGOs differentiated prematurely in PIC hydrogels affecting their self-renewal capacity. Similarly, SGOs show decreased expression of immediate early genes (IEGs) after culture in PIC hydrogels. Activation of multiple signalling pathways involved in IEG expression by β-adrenergic agonist isoproterenol, led to increased stem cell self-renewal capacity as measured by organoid forming efficiency (OFE). These results indicate that PIC hydrogels are promising 3D matrices for SGOs, with the option to be used clinically, after further optimization of the hydrogel and culture conditions.
Investigating the involvement of cognitive control processes in innovative and adaptive creativity and their age-related changes

Introduction Based on the two-factor model of creativity, two distinct types of creative problem solving can be differentiated: innovative (“do things differently”) and adaptive (“do things better”). Flexible cognitive control is a crucial concept in connection with both general and specific styles of creativity: innovative problem-solving benefits from broader attention and flexible mental set shifting; while adaptive creativity relies on focused attention and persistent goal-oriented processes. We applied an informatively cued task-switching paradigm which is suitable for measuring different cognitive control processes and mechanisms like proactive and reactive control. We hypothesized that adaptive creativity is connected to effective proactive control processes, while innovative creativity is based on reactive task-execution. As we have found no previous evidence how age-related changes in cognitive control affects creative cognition; we also examined the effect of healthy aging on different problem-solving styles in an explorative way. Methods Our participants, 37 younger (18–30 years) and 37 older (60–75 years) adults, were divided into innovative and adaptive creative groups according to the Torrance Test of Creative Thinking’s Figural Subtest (Hungarian version). Results Our results showed that among younger adults the adaptively creative group had larger cue-locked CNV component (effective preparatory activity connected to proactive control), while the innovatively creative group had a larger target-locked P3b component (effective target evaluation and categorization in line with reactive control) which supports a functional difference in the two creative styles. By contrast, in older adults innovative problem-solving showed larger mixing costs (less effective maintenance and selection of task sets), and the lack of trial type effect on target-locked N2b (target-induced goal reactivation and less effective conflict resolution); while adaptive problem-solving caused them to make fewer errors (accuracy-oriented behavior). Discussion All in all, innovative and adaptive creativity is based on distinct cognitive control mechanisms in both age-groups, but their processing level is affected by age-related changes.
Prognostic value of heart rate variability in atrial fibrillation recurrence following catheter ablation: A systematic review and meta-analysis

Background Atrial fibrillation (AF) has been a worldwide health issue with increasing prevalence and mortality. Recently, increasing attention has been gained to the relationship between heart rate variability (HRV) and the clinical prognosis of AF catheter ablation. We aimed to evaluate the prognostic value of HRV in AF recurrence. Methods We systematically searched Web of Science, PubMed, and Embase from inception until 17 August 2022 to conduct the systematic review and meta-analysis. We included the studies reporting the predictive value of HRV parameters for AF recurrence or in which HRV parameters in AF recurrence and non-recurrence groups were individually reported. Results Finally, we enrolled 16 studies, including 2,352 patients. Higher rMSSD could independently predict AF recurrence following catheter ablation (OR: 1.02, 95% CI: 1.00–1.04; p = 0.03). Higher HF (OR: 1.55, 95% CI: 1.05–2.28; p = 0.03) and lower LF/HF (OR: 1.12, 95% CI: 1.03–1.20; p = 0.004) could independently predict AF recurrence within 1 year. Higher SDNN (OR: 1.02, 95% CI: 101–1.02; p = 0.0006) could independently predict AF recurrence among patients with paroxysmal AF. Almost all HRV parameters within 3 days after catheter ablation and lnHF, lnLF, and rMSSD at 3 months after catheter ablation performed significant differences in AF recurrence and non-recurrence groups. Conclusion Heart rate variability, especially higher rMSSD (within short-term and long-term periods), was closely related to recurrent AF following catheter ablation, highlighting the clinical importance of HRV in the prognosis of AF following catheter ablation.