Miracle-dz/UniFAR-FTUs huggingface dataset:
Emergency Surgery Score as an Effective Risk Stratification Tool for Patients Undergoing Emergency Surgeries: A Narrative Review

Several risk stratification tools have been described for quantifying perioperative morbidity, mortality, and adverse events in patients undergoing elective and emergency surgeries. These tools help in decision-making, determining the prognosis and communicating it with patients and family members, and planning admissions to the intensive care units (ICU) if necessary. Emergency surgery poses quite a unique challenge in terms of deranged physiology, age, and comorbid conditions, and often carries a higher incidence of morbidity and mortality. Very few risk stratification tools are available to reliably predict the risk posed by emergency surgical interventions. One of the recently described tools is the Emergency Surgery Score (ESS), which comprises three demographic variables, 10 comorbidities, and nine laboratory variables, the scores of which add up to 29. Several studies have demonstrated that ESS reliably predicts morbidity, mortality, and the need for ICU admission, predicting infectious complications like pneumonia and renal failure. In this review, we analyze the current literature to investigate the efficacy and reliability of ESS as a risk stratification tool for patients undergoing emergency surgeries.
Stationary wave biases and their effect on upward troposphere– stratosphere coupling in sub-seasonal prediction models

Abstract. The simulated Northern Hemisphere winter stationary wave (SW) field is investigated in 11 Subseasonal-to-Seasonal (S2S) prediction project models. It is shown that while most models considered can well simulate the stationary wavenumbers 1 and 2 during the first 2 weeks of integration, they diverge from observations following week 3. Those models with a poor resolution in the stratosphere struggle to simulate the waves, in both the troposphere and the stratosphere, even during the first 2 weeks. Focusing on the tropospheric regions where SWs peak in amplitude reveals that the models generally do a better job in simulating the northwestern Pacific stationary trough, while certain models struggle to simulate the stationary ridges in both western North America and the North Atlantic. In addition, a strong relationship is found between regional biases in the stationary height field and model errors in simulated upward propagation of planetary waves into the stratosphere. In the stratosphere, biases are mostly in wave 2 in those models with high stratospheric resolution, whereas in those models with low resolution in the stratosphere, a wave 1 bias is evident, which leads to a strong bias in the stratospheric mean zonal circulation due to the predominance of wave 1 there. Finally, biases in both amplitude and location of mean tropical convection and the subsequent subtropical downwelling are identified as possible contributors to biases in the regional SW field in the troposphere.
Diagnosis and Treatment of Five Pain-Related Conditions in Urban China: A Population-Based Cross-Sectional National Health and Wellness Survey

Background While there is an extensive body of research regarding pain and its treatment in developed countries, little research on this topic has been performed in developing countries. This study aimed to investigate the diagnosis, treatment, and treatment satisfaction in individuals with pain in urban China using real-world data. Methods All respondents from the 2013, 2015, and 2017 China National Health and Wellness Survey were included in the analysis and were classified into diagnosed and undiagnosed groups according to their self-reported physician diagnosis or experience in the past month. The following five categories of pain were analysed: headache, cancer-associated pain, musculoskeletal pain, neuropathic pain, and fibromyalgia. Rates for diagnosis, treatment, and satisfaction with medication were calculated overall and for each pain type. Results A total of 3802 respondents reported experience of at least one type of pain in the past month. Among those, 61.2% were diagnosed with a pain-related condition, the majority of which (84.0%) were receiving treatment. For diagnosed respondents taking over-the-counter and/or prescription medication, 70.3% were satisfied with their treatment. Comparing between pain types, the diagnosis rates for cancer-associated pain (32.7%) and fibromyalgia (22.8%) were relatively low, whereas respondents with musculoskeletal pain has the highest diagnosis rate (61.1%). Respondents with cancer-associated pain had the lowest satisfaction (30.0%) with over-the-counter and prescription medication, while respondents with headache (76.2%) had the highest satisfaction rate with such medications. Conclusion Our study highlights the importance of raising awareness for pain management as well as education and training for healthcare providers and patients.
Resurrection of Passifloraacuminata DC. and synonymization of P.tolimana Harms, P.gleasonii Killip, P.metae M. Bonilla, C. Aguirre & Caetano (Passifloraceae) following a study of their morphology and ecogeography

﻿Abstract Within the very uniform series Laurifoliae, Passifloraacuminata (treated as a synonym of P.laurifolia in the Flora of China), P.tolimana, P.gleasonii and P.metae appear particularly similar. A review of their descriptions and the associated specimens confirms their lack of morphological differentiation and leads us to formally resurrect P.acuminata and place the three other taxa under its synonymy. This taxonomic move is also supported by a revision of 72 additional geolocalized specimens (for a grand total of 78) and an analysis of their distribution and habitats. In fact, the bioclimatic space corresponding to the specimens previously assigned to P.acuminata encompasses that of all specimens previously assigned to the three other taxa under study. The species range covers a wide region, comprising the lower Amazon and the north of its basin, mostly below 200 m, and, to the west, in the upper Amazon, the Orinoco basin, and along the Andean foothills and valleys, from Venezuela to Peru, at elevations between 100 and 2200 m. In the lowlands, the species appears associated with white sand savannas and water courses. A more complete description is proposed for the species, including its unusual fusiform and slightly ribbed fruit. Another rare trait in the series Laurifoliae is that the outer corona filaments tend to be longer than the corolla.
Genomic Survey and Microsatellite Marker Investigation of Patagonian Moray Cod (Muraenolepis orangiensis)

Simple Summary Patagonian moray cod is known to inhabit the cold waters near Antarctica, and it belongs to the Muraenolepis genus. This genus has seven species, and five of them are recently reported. The Muraenolepis genus has similar morphological characters, and this is a limitation of taxonomical classification. In this study, a genome survey and microsatellite marker analysis were conducted to characterize the genome profile for classification. As a result, genomic data such as genome size and microsatellite motifs were obtained. Abstract The Muraenolepididae family of fishes, known as eel cods, inhabits continental slopes and shelves in the Southern Hemisphere. This family belongs to the Gadiformes order, which constitutes one of the most important commercial fish resources worldwide, but the classification of the fish species in this order is ambiguous because it is only based on the morphological and habitat characteristics of the fishes. Here, the genome of Patagonian moray cod was sequenced using the Illumina HiSeq platform, and screened for microsatellite motifs. The genome was predicted to be 748.97 Mb, with a heterozygosity rate of 0.768%, via K-mer analysis (K = 25). The genome assembly showed that the total size of scaffolds was 711.92 Mb and the N50 scaffold length was 1522 bp. Additionally, 4,447,517 microsatellite motifs were identified from the genome survey assembly, and the most abundant motif type was found to be AC/GT. In summary, these data may facilitate the identification of molecular markers in Patagonian moray cod, which would be a good basis for further whole-genome sequencing with long read sequencing technology and chromosome conformation capture technology, as well as population genetics.
Rise of clathrodictyid stromatoporoids during the Great Ordovician Biodiversification Event: insights from the Upper Ordovician Xiazhen Formation of South China

Abstract. Clathrodictyids are the most abundant stromatoporoids in the Upper Ordovician Xiazhen Formation (middle to upper Katian) of South China. A total of nine species belonging to four clathrodictyid genera are identified in the formation, including Clathrodictyon idense Webby and Banks, 1976, Clathrodictyon cf. Cl. microundulatum Nestor, 1964, Clathrodictyon cf. Cl. mammillatum (Schmidt, 1858), Clathrodictyon megalamellatum Jeon n. sp. , Clathrodictyon plicatum Webby and Banks, 1976, Ecclimadictyon nestori Webby, 1969, Ecclimadictyon undatum Webby and Banks, 1976, Camptodictyon amzassensis (Khalfina, 1960), and Labyrinthodictyon cascum (Webby and Morris, 1976). The clathrodictyid fauna in the Xiazhen Formation is very similar to those from both New South Wales and Tasmania, although the latter two Australian regions do not share any common clathrodictyid species during the Late Ordovician. The paleobiogeographic pattern indicates that the northward drift of South China resulted in a favorable environment for the migration of clathrodictyids from other peri-Gondwanan terranes to South China. In addition, these peri-Gondwanan clathrodictyid species hosted various endobionts, representing a variety of paleoecological interactions. The high abundance and species-level diversity of clathrodictyid species presumably increased the substrate availability of suitable host taxa, judging from the diverse intergrowth associations between clathrodictyids and other benthic organisms. These paleoecological interactions between stromatoporoid and other organisms are known from the Late Ordovician and became more abundant and widespread in the Siluro–Devonian. Overall, the Late Ordovician clathrodictyid assemblage in South China demonstrates one of the highest species-level diversities among all peri-Gondwanan terranes and represents a precursor of the complex, clathrodictyid-dominated communities of later metazoan reefs during the Great Ordovician Biodiversification Event.
Effects of Photovoltaic Solar Farms on Microclimate and Vegetation Diversity

The need for energy and the increasing importance of climate change mitigation are leading to a conversion from conventional to renewable energy sources. Solar photovoltaic (PV) power has seen the most significant increase among all renewable energy sources. However, most of these installations are land-based, significantly changing global land use (LU). The real impacts, whether positive or negative, are poorly understood. This study was undertaken to have a better understanding of the impacts of solar parks on the microclimate and vegetation dynamics. First, different solar parks were visited to take measurements of the surface temperature (Tsurf), photosynthetic active radiation (PAR), air temperature (Tair), and humidity (RH) to quantify the microclimate and perform a vegetation relevé. The measurements were taken at different positions: underneath, in between, and outside solar panels. For vegetation, the data were first converted to diversity indices, which in turn contributed to a multi-indicator land use impact assessment that evaluated effects on vegetation, biodiversity, soil and water. Solar parks had clear effects on microclimate: if the panels were high enough from the ground, they could lower the Tsurf by providing shade and enough airflow. Additionally, the multidimensional functional diversity (FD) analysis of the vegetation indicated that there was less light at a higher humidity and lower temperature underneath the panels. Interestingly, the species underneath the panels also preferred a lower pH and a higher nitrogen level. Finally, the land use impact assessment found that the total land use impact for a wheat field was higher than that of the solar park, which suggests that the conversion of conventional intensive agriculture to a solar park would be beneficial.
The Prevalence of Malnutrition, Nutrient Intakes and Deficiencies of Thai Children with Cerebral Palsy, at QSNICH

Objective: To evaluate the prevalence of malnutrition, nutrient intakes, and deficiencies of Thai children with cerebral palsy (CP), at QSNICH. Materials and Methods: A cross-sectional study was performed in Thai children diagnosed CP at Neuro-clinic, QSNICH. Collecting demographic, previous 3-day food record, feeding, anthropometric data, physical examinations, and laboratory investigations. Nutritional status was assessed using WHO growth references (2007). Nutrient intakes were analyzed by program IMMUCAL. Results: Twenty-three children diagnosed CP were included. Sixty-one percent were boys and 39% were girls. The mean age was 63±31 months. Sixty-one percent had feeding problems. Twenty cases (87%) were oral feeding. Energy distribution of carbohydrate, fat, and protein was 46, 38, and 16, respectively. Daily intakes of nutrients were inadequate, such as calcium at 78%, iron at 35%, vitamin C at 26%, vitamin A and B1 at 22%, energy at 13%, and protein vitamin B2 and B3 at 9%. Malnutrition revealed that 52% were underweight and 35% were stunting. Glossitis, dental caries, and gingivitis were found in 65%, 56%, and 26%, respectively. Laboratory investigations revealed anemia in 13%, iron deficiency in 9%, and vitamin C deficiency in 22%. Malnutrition was not statistically significantly related to energy intake, feeding problems, and route. Energy intake above 100% DRI was related to normal length (p=0.019). Conclusion: Children with CP commonly had malnutrition and nutrient deficiencies due to inadequate intakes. Proper nutritional support with balanced diet will prevent malnutrition and promote health of these children. Keywords: Cerebral palsy; Malnutrition, nutrient intakes; Nutrient deficiencies; Thai children
Clinical Application of Induced Hepatocyte-like Cells Produced from Mesenchymal Stromal Cells: A Literature Review

Liver disease is a leading cause of mortality worldwide, resulting in 1.3 million deaths annually. The vast majority of liver disease is caused by metabolic disease (i.e., NASH) and alcohol-induced hepatitis, and to a lesser extent by acute and chronic viral infection. Furthermore, multiple insults to the liver is becoming common due to the prevalence of metabolic and alcohol-related liver diseases. Despite this rising prevalence of liver disease, there are few treatment options: there are treatments for viral hepatitis C and there is vaccination for hepatitis B. Aside from the management of metabolic syndrome, no direct liver therapy has shown clinical efficacy for metabolic liver disease, there is very little for acute alcohol-induced liver disease, and liver transplantation remains the only effective treatment for late-stage liver disease. Traditional pharmacologic interventions have failed to appreciably impact the pathophysiology of alcohol-related liver disease or end-stage liver disease. The difficulties associated with developing liver-specific therapies result from three factors that are common to late-stage liver disease arising from any cause: hepatocyte injury, inflammation, and aberrant tissue healing. Hepatocyte injury results in tissue damage with inflammation, which sensitizes the liver to additional hepatocyte injury and stimulates hepatic stellate cells and aberrant tissue healing responses. In the setting of chronic liver insults, there is progressive scarring, the loss of hepatocyte function, and hemodynamic dysregulation. Regenerative strategies using hepatocyte-like cells that are manufactured from mesenchymal stromal cells may be able to correct this pathophysiology through multiple mechanisms of action. Preclinical studies support their effectiveness and recent clinical studies suggest that cell replacement therapy can be safe and effective in patients with liver disease for whom there is no other option.
Fourth Generation Evaluation of Health Services: Exploring a Methodology That Offers Equal Voice to Consumer and Professional Stakeholders

This article explores the need for a clear understanding of fourth generation evaluation as a necessary requirement for those hoping to achieve an effective analysis of health services. The weaknesses of the traditional approaches to evaluation are fully examined so that an effective choice of evaluation methodology can be made. Current health service thinking highlights the need to recognize the importance of both consumer and professional stakeholders, allowing each an equal voice. The authors aim to assist evaluators to select a methodology that will be the most effective medium for allowing this to occur.
Mediating effect of entrepreneurial social identity on the MSME-owners’ attitude and resilience amid COVID-19 crisis

ABSTRACT The COVID-19 pandemic has shaken most firms worldwide. The lockdown and community quarantine put micro-, small, and medium-sized enterprises (MSMEs)’ resilience to the test. With nonessential businesses closed and all consumers isolated, the survival of businesses remains at risk. As owners are challenged to survive, contradictory perspectives on the resiliency of small and medium-sized enterprises during adversity emerge. This study aims to determine the moderating effect of entrepreneurial social identity on the relationship between perceived attitude and resilience behavior of business owners. According to the findings, MSMEs’ perseverance led to a structure that maximizes technology and expands community network. The result shows MSMEs’ vitality and resilience during COVID-19. Evidently, the mediating effect of entrepreneurial social identity enhanced the resilience of the owners, which resulted in technology-based opportunities and re-creation of community-based enterprises. Indirectly, but significantly, the creativity and self-sufficiency of MSME owners contributes to the reduction of poverty and unemployment.
Applying systems engineering in the civil engineering industry: an analysis of systems engineering projects of a Dutch water board

ABSTRACT The past decade, practice and literature have shown an increasing interest in Systems Engineering (SE) in the civil engineering industry. The aim of this study is to analyse to what extent SE is applied in six civil engineering SE projects of a Dutch water board. The projects were analysed using a framework that was developed from existing SE literature. The projects that scored highest on the application of SE were those where the project leader was highly motivated to apply SE, where top management support for SE was arranged, and where an experienced engineering consulting firm was involved. The lowest scoring project was a routine project in which project team members considered the use of SE unnecessary. To improve SE implementation and execution in organisations, it is recommended to arrange top management support for SE, to enhance the SE skills of employees, and to establish clear SE standards and procedures.
Understanding the Palatability, Flavor, Starch Functional Properties and Storability of Indica-Japonica Hybrid Rice

The rice quality and starch functional properties, as well as the storability of three YY-IJHR cultivars, which included YY12 (biased japonica type YY-IJHR), YY1540 (intermedius type YY-IJHR) and YY15 (biased indica type YY-IJHR), were studied and compared to N84 (conventional japonica rice). The study results suggested that the three YY-IJHR varieties all had greater cooking and eating quality than N84, as they had lower amylose and protein content. The starch of YY-IJHR has a higher pasting viscosity and digestibility, and there was a significant difference among the three YY-IJHR cultivars. Rice aroma components were revealed by GC-IMS, which indicated that the content of alcohols vola-tile components of YY-IJHR were generally lower, whereas the content of some aldehydes and esters were higher than N84. In addition, YY-IJHR cultivars’ FFA and MDA contents were lower, which demonstrated that YY-IJHR had a higher palatability and storability than those of N84 in fresh rice and rice stored for 12 months. In conclusion, this study suggested that YY-IJHR had better rice quality and storability than N84. PCA indicated that the grain quality and storability of YY12 and YY15 were similar and performed better than YY1540, while the aroma components and starch functional properties of YY-IJHR cultivars all had significant differences.
Dengue Virus-2 Infection Affects Fecundity and Elicits Specific Transcriptional Changes in the Ovaries of Aedes aegypti Mosquitoes

Dengue fever (DF), caused by the dengue virus (DENV), is the most burdensome arboviral disease in the world, with an estimated 400 million infections each year. The Aedes aegypti mosquito is the main vector of DENV and transmits several other human pathogens, including Zika, yellow fever, and chikungunya viruses. Previous studies have shown that the pathogen infection of mosquitoes can alter reproductive fitness, revealing specific vector-pathogen interactions that are key determinants of vector competence. However, only a handful of studies have examined the effect of DENV infection in A. aegypti, showing a reduction in lifespan and fecundity over multiple blood meals. To provide a more comprehensive analysis of the impact of DENV infection on egg laying and fecundity, we assessed egg laying timing in DENV-2 blood-fed mosquitoes (infected group) compared to mock blood-fed mosquitoes (control group). We confirmed a significant decrease in fecundity during the first gonadotrophic cycle. To further investigate this phenotype and the underlying DENV-2 infection-dependent changes in gene expression, we conducted a transcriptomic analysis for differentially expressed genes in the ovaries of A. aegypti infected with DENV-2 vs. mock-infected mosquitoes. This analysis reveals several DENV-2-regulated genes; among them, we identified a group of 12 metabolic genes that we validated using reverse transcription-quantitative PCR (RT-qPCR). Interestingly, two genes found to be upregulated in DENV-infected mosquito ovaries exhibited an antiviral role for DENV-2 in an Aedes cell line. Altogether, this study offers useful insights into the virus-vector interface, highlighting the importance of gene expression changes in the mosquito’s ovary during DENV-2 infection in the first gonadotrophic cycle, triggering antiviral responses that may possibly interfere with mosquito reproduction. This information is extremely relevant for further investigation of A. aegypti’s ability to tolerate viruses since virally infected mosquitoes in nature constitute a powerful source of supporting viruses during intra-epidemic periods, causing a huge burden on the public health system. Graphical Abstract Aedes aegypti first gonadotrophic cycle is altered by DENV-2 infection.