Miracle-dz/UniFAR-FTUs huggingface dataset:
Scientific output of professors and doctors habilitatus from Medical University of Silesia in Katowice – School of Medicine with Division of Dentistry in Zabrze

A I M : The purpose of the study was to present the scientific output of professors and doctors habilitatus and to assess the factors influencing scientific output. M A T E R I A L A N D M E T H O D S : The data of scientific output (full text papers from the Web of Science and Scopus) of scientists were presented. R E S U L T S : The mean scientist’s age was 55.7 ± 7.2 yrs, the mean age of receiving PhD 32.7 ± 3.2 yrs, the age of obtaining habilitation degree 45.8 ± 5.6 yrs, the age of attaining professorship 51.2 ± 5.9 yrs, the interval from PhD to habilitation 13.1 ± 4.9 yrs, the interval from habilitation to professorship 7.7 ± 2.7 yrs, the total number of publications 144.6 ± 124.2, the number of publications with an Impact Factor 33.8 ± 31.3, the total value of Impact Factor 61.7 ± 73.2, the citation index 387 ± 531 and index h 8.6 ± 5.3 according to the Web of Science, the citation index 513 ± 756 and index h 9.6 ± 6.0, according to Scopus, the citation index 411 ± 601 and index h 8.6 ± 5.2, according to Scopus without citations of all co-authors. In a correlation analysis, a lower age of habilitation (r ranged -0.29 to -0.36, p < 0.01) and of professorship (r ranged 0.31 to -0.42, p < 0.05) improved the scientific output. Shorter intervals from PhD to habilitation and from habilitation to professorship improved the scientific output as well (r ranged -0.25 to -0.34, p < 0.01, r ranged -0.41 to -0.53, p < 0.01, respectively). Received: 11.02. 2016 Revised: 15.03.2016 Accepted: 25.03.2016 Published online: 28.06. 2016 Adress for corespondence : Prof. dr hab. n. med. Wojciech Pluskiewicz, Department of Metabolic Bones Diseases, Department of Internal Medicine, Diabetology and Nephrology School of Medicine with the Division of Dentistry in Zabrze, Medical University of Silesia in Katowice, ul. 3 Maja 13/15, 41-800 Zabrze, tel. +48 32 370 44 88, e-mail: osteolesna@poczta.onet. pl Copyright © Śląski Uniwersytet Medyczny w Katowicach www.annales. sum.edu. pl ANN. ACAD. MED. SILES. (online) 2016; 70: 113–117 114 C O N C L U S I O N : Scientific output increases with a lower age of habilitation and shorter intervals between PhD and habilitation and habilitation and professorship. The current results should help modify scientific politics supporting the total research impact of the whole division. KEY WO RDS citation index, index h, scientific output, Scopus, Web of Science
Assessment of the Performance of Specific Prostate Diagnostic Tools in the Detection of Prostate Cancer among Ghanaian Men

Aims: This study evaluated the individual and combined performances of specific prostate diagnostic tools in the detection of prostate cancer among Ghanaian men. Study Design: A hospital-based cross-sectional prospective study. Methodology: A total of 241 patients suspected of having prostate cancer (PCa) due to abnormal digital rectal examination (DRE) and, or elevated prostate specific antigen (PSA) level underwent Trans rectal ultrasonography guided biopsy of the prostate. Evaluation of PSA, Prostate Specific Antigen Density (PSAD), DRE, prostate volume was done using receiver operating characteristics curve analysis These four diagnostic tools were combined into a single score to improve the diagnostic performance. Results: Prostate cancer was diagnosed in 63 patients out of 241 (26.1%). Significantly elevated levels of PSA and PSAD were observed among patients with PCa compared to patients without PCa. PSAD showed better accuracy (AUC= 78.9) followed by PSA (AUC=77.8) and DRE (AUC=68.6) respectively for the individual diagnostic tools. PSAD had sensitivity and specificity of 84.1% and 56.7% respectively. Among the different combination of diagnostic tools, bioscore combination of DRE+PSAD+PSA had better accuracy (AUC=80.6) followed by PSAD+DRE (AUC=78.1) PSA+PSAD+DRE+ Prostate Volume (AUC= 76.7), and for PSAD+PSA (AUC=71.5) respectively. PSA on its own had a sensitivity of 98.4% and specificity of 16.3% respectively. The best statistically significant (p<0.05) odds ratio (OR) for the combination of PSAD+DRE was 33.40 followed by PSA+PSAD at 19.52 and PSA+DRE at 13.67 respectively. Conclusion: Combined diagnostic performance of DRE+PSAD+PSA poses a better diagnostic accuracy. Bioscores for the combination of the diagnostic tools were significantly associated with increasing odds of prostate cancer detection upon logistic regression analysis. Further studies are required to evaluate the combine diagnostic performance in larger population.
Dementia in general practice: incidence, prevalence, social prevalence and co-morbidity

Age specific prevalence and incidence figures for dementia were investigated for people aged 50 or more within the Registration Network of Family Practices (RNH), a computerized registration network of 15 general practices in the Netherlands. Point prevalence was 7.6‰ (95% Cl = 6.2-9.0) and cumulative incidence was 2.0 per 1 000 persons per year (95% Cl = 1.8-2.4). Both prevalence and incidence increase with age and are higher in women than in men. Dementia tends to be more frequent in people with a lower education, although this finding is not statistically significant (p = 0.08). A complex interaction exists between age and type of household, dementia being more frequent in people living with others at older age (age 80 and more) and in people living alone at younger age. There are no arguments for a relation between dementia and a general susceptibility for disease, as estimated by the number of health problems known to the GP or between dementia and (clusters of) specific diseases.
Role of peroxisome proliferator-activated receptor γ in lung epithelial cells.

s presented at: British Pharmacology Society, Bath. U.K. (2004) International Cytokine Society Annual Meeting, Dublin, Ireland (2003) (2 Posters) International Association of Inflammation Societies6th World Congress on Inflammation, Vancouver, Canada (2003) British Society for Immunology Annual Congress, Harrogate. U.K. (2002) Biochemical Society PI3-K meeting, Horsham, U.K. (2002)
Chapter 25 Use of IgY Antibodies in Human and Veterinary Medicine

IgY technology, including the production and use of polyclonal IgY antibody (Ab), is a highly innovative and an expanding branch of biotechnology. In this chapter, we will discuss the advantages in the use of IgY Ab and the application of IgY in human and veterinary medicine (see also Kovacs-Nolan and Mine 2004). Other aspects such as immunization procedures, Ab titer development, IgY heat and acid stability and preservation of IgY solutions are reviewed in detail in Chacana et al. (2004), Hau and Hendriksen (2005), Leenars et al. (1999), Schade et al. (2000), and Schade et al. (2005). The usefulness of IgY Abs in biomedical diagnostic is well documented by an increasing quantity of literature and is therefore not included in this review.
Musculoskeletal Symptoms and Related Factors of Golf Caddies

Objectives: This study evaluated the complaint rates of musculoskeletal symptoms and investigated the related factors of musculoskeletal symptoms in the caddies. Methods: For 316 caddies working at 6 regular golf courses, we used the self-recording questionnaires to examine general characteristics, job stress factors, subjective musculoskeletal symptoms designed by NIOSH, working environments, and working contents. Results: The complaint rates of musculoskeletal symptoms according to the musculoskeletal criteria of NIOSH were 41.8% in the leg/knee/ankle/foot, 35.8% in the shoulder, 35.8% in the upper back/lower back, 28.8% in the neck, and 28.5% in the arm/wrist/fingers. Important factors affecting musculoskeletal symptoms were daily working hours during the high-demand season in all anatomical sites except the arm/wrist/fingers. Other related factors were degrees of winding and inclined in the golf courses, violent language and violence of customers, inability to regulate the velocity and work load control, heavy physical burden, instability of employment, and possibility of unemployment according to the specialty of caddies. As a results of multivariate logistic regression analysis, musculoskeletal symptoms of the neck, shoulders, back/lower back and leg/knee/ankle/foot were significantly influenced by working time over 12 hours in the high-demand season, and symptoms of the arm/wrist/fingers by low decision latitude (P<0.05). Conclusions: The complaint rates of musculoskeletal symptoms in the caddies were affected by working time over 12 hours and low decision latitude against excessively high psychological job demand.
Heterogeneity of acquired KRAS and EGFR mutations in colorectal cancer patients treated with anti-EGFR monoclonal antibodies.

3512 Background: Although KRAS and EGFR extracellular domain acquired mutations were detected in two small cohorts and correlated with acquired resistance to anti-EGFR monoclonal antibodies (MAb), the frequency, co-occurrence, and distribution of these acquired mutations is unknown. In this study we evaluated the presence of acquired KRAS and EGFR mutations in cfDNA from CRC patients (pts) treated with anti-EGFR monoclonal antibody. Methods: Plasma was collected from EGFR-MAb refractory mCRC pts as part of the ATTACC (Assessment of Targeted Therapies Against Colorectal Cancer) program. Eligible pts had documentation of pre-treatment KRAS wild type tumor. The cfDNA was extracted from the plasma and analyzed by BEAMing technology for acquired KRAS and EGFR mutation. Results: The plasma from 55 patients was analyzed for EGFR and KRAS mutation. The S492R EGFR mutation was detected in 4 pts (7%) treated with cetuximab. Acquired KRAS mutations were detected in 26 of the 55 KRAS wt samples analyzed (47%). Althou.
EXERCISE AND SWEATING

運動を始めると,き わめて短い潜時で発汗活動 が増加する. こ れは深部体温や皮膚温の上昇に先 行する. す なわち,深 部体温(鼓 膜温や食道温) の上昇はかなり遅れるし,む しろしばしば一過性 に下降する. 皮 膚温も皮膚血管収縮のため,運 動 初期には通常下降する. そ れに対 し,発 汗は体温 が上昇に転ずる前に出現 し,ま た,そ の後の発汗 増加も深部体温の上昇過程に先立つ. と くに運動 開始前から発汗 しているときは,運 動開始後直ち に発汗量が増加 し始める. た だし,深 部温の初期 低下が著しいときは,多 少遅れたり一旦減少 した りることもある64)(図1). 運 動負荷の急増,急 減に際しても同様に迅速な発汗反応がみられる. また正弦波状に周期的に負荷を変えた運動でも発 汗応答は体温,皮 膚温変動に先行するし,負 荷の 変動周期が短いと体温,皮 膚温の変動なしに発汗 応答が認められる85). このような発汗反応は,活 動肢の血行 を阻止 し て深部体温の上昇を防いでも起 こる79). し か も 筋や静脈壁に温度受容器の存在は認められていな いので,筋 温自体の上昇に起因する可能性 も少な い. し たがって,運 動初期の発汗活動になんらか の温熱以外の要因が関与していると推測 される. 筋や関節の機械受容器の刺激に基づ く反射的な 発汗促進の可能性も古 くから指摘 されたが,受 動 運動では体温上昇に見合う程度の発汗量の増加 し かみ られ ない ことか ら,こ の可 能性 も疑 わ し い67). 運動開始時の発汗活動増大は一過性であるとみ なし,運 動開始に伴 う運動中枢の興奮が体温調節 のセ ットポイントに影響 を与え,こ れが一過性に 低下するとの仮説が提唱された り8),ま た交感神 経系発射の増加が関与すると説明された り74), さらには運動開始時の精神興奮に起因すると説明 された りする. 手掌や足底は精神性発汗部位 として知られる が,運動初期にしばしば一過性の発汗増加を示す. 一般体表面でも精神興奮時に一過性の反応(増 加
The impact of hydrotherapy on a patient’s perceived well-being: a critical review of the literature

Background: Physiotherapists commonly use hydrotherapy as a treatment approach for various types of conditions. As hydrotherapy utilizes the hydrodynamic properties of water to promote relaxation and decrease pain perception, previous research has suggested that hydrotherapy may help to decrease the health burden of musculoskeletal (MSK) conditions. The aim of this review was to critically examine literature investigating (a) the benefits of hydrotherapy on reducing pain and disability associated with chronic MSK conditions, and (b) report on literature findings regarding the perceived benefit of hydrotherapy on the well-being of adults with chronic MSK conditions. Methods: Select electronic databases were searched to identify relevant articles. Studies meeting the inclusion criteria were critically analyzed using the Downs and Black protocol with agreement between raters assessed via Kappa analysis. Results: Nine original articles addressing the benefits of hydrotherapy on adult populations with chronic MSK conditions were analyzed. The mean critical appraisal score was 73% (κ = 0.87) with the evidence suggesting that hydrotherapy had a positive effect on pain, quality of life, condition-related disability and functional exercise capacity. It was also noted that following hydrotherapy, the perceived benefit of well-being was superior to land-based exercise protocols in cases where water temperature was within a thermoneutral range (33.5–35.5 °C). Conclusion: Hydrotherapy helps to reduce the health burden of MSK conditions. Improvements in the perception of well-being are likely to occur following hydrotherapy that is conducted in water within the thermoneutral range.
THE EFFECT OF EDUCATION ON BASE THE THEORY OF PLANNED BEHAVIOR TOWARD NORMAL DELIVERY IN PREGNANT WOMEN WITH INTENTION ELECTIVE CESAREAN

Introduction: Finding an appropriate training method for encouraging pregnant women toward performing vaginal delivery is necessary because of increasing growth of cesarean and its associated complications. Methods: This semi- experimental study was carried out on a sample of 200 pregnant women who referred to the obstetrics offices of Zahedan during winter 2010 to summer 2011 by using non- probability sampling. Intervention group received training according to theory of planned behavior. After doing pretest using a validated and reliable questionnaire in both groups. Post- test was conducted after one month in both study groups. T-test, Chi-Square and Logestic regression were used for data analysis. Results: Findings showed a significant statistical differences between two groupsr knowledge, attitude and perceived behavior control, subjective norms and behavior scores after intervention (P<0.001). Regression analysis revealed that behavioral intention and perceived control were two greatest predictors of behavior. Overall, natural delivery was seen in 22 of women in intervention group compared with 4 in control group. Conclusion: The study finding showed that, education based on theory of planned behavior significantly increased natural delivery among study participants. Accordingly, it is recommended to adapt a policy which pregnant women to receive elective cesarean section training packages according to this theory and attend related group discussions
A comparative effectiveness secondary data analysis: Selected short term economic and clinical outcomes of rapid surgical intervention in the geriatric fracture population

The percentage of the U.S. population that is over 65 years of age is expected increase to over 20% by 2040. Within that geriatric population, 50% of women and 20% of men will experience osteoporotic fractures. The cost of their care is estimated in billions of dollars annually. The outcomes from osteoporotic fractures account for more morbidity than all cancers, except lung cancer, combined. Rapid surgical intervention protocols, which reduce the time between fracture and surgical repair, are intended to improve outcomes and reduce costs. The protocols require intense care coordination and their effectiveness has not been unequivocally established. This study explored the relationships of rapid surgical intervention to the clinical outcomes of in-hospital delirium and pressure ulcer and the economic outcomes of post-procedure length of stay and total hospital charges. These outcomes were investigated through a secondary data analysis of the New York State administrative billing database (SPARCS) from a five-hospital system. The sample included 1,979 subjects from the years of 2010 through 2013; a modified Charlson Co-morbidity and Age Index score was applied to all subjects in order to approximate their admission health status. Rapid Surgical Intervention was a predictor (p < .001) of lower post-procedure lengths of stay lower total hospital charges, and lower rates of pressure ulcer development. High Modified Charlson Index scores were predictive of higher mortality rates, longer lengths of stay, and higher total charges. Male gender was significant for higher lengths of stay, mortality rates, and pressure ulcer development. Femur/hip fractures were related to longer lengths of stay and higher total charges than other fracture sites, but were not a predictor of mortality or pressure ulcer development.
Eating Habit and Stress Status according to Exercising Habits of Middle-Aged Adults in Chungnam

This study aimed to evaluate the health concern, eating habits, dietary behavior, and psychological stress among middleaged adults in Chungnam according to their exercise status. A total of 437 adults with a mean age of 42.6 years participated in this study and completed a questionnaire survey. The subjects were divided into one of three groups according to their exercise status: never doing exercise (NDE; n=144), doing exercise once a week (DEO; n=186), and doing exercise twice a week or more (DET; n=107). Results demonstrated significant differences in concern about health, subjective health status, meal regularity, dietary problems, and stress score among the three groups. The DET and DEO groups were more concerned about their health (p<0.001), and had a perception that their health status was better than that of the NDE group (p<0.01). A larger percentage of the DET group had breakfast everyday (p<0.05) and a smaller percentage of the DET group had dietary problems such as irregular mealtime and skipping meals (p<0.01), compared to the other groups. The average stress score of the DET group was significantly lower than that of the DEO and NDE groups (p<0.05). The results reveal that doing regular exercising at least twice a week is associated with higher health concern, more desirable dietary habits, and lower psychological stress in middle-aged adults. These findings support the beneficial effects of regular exercise for health, dietary habits, and stress control.
Acute Resistance Exercise Program Variables and Subsequent Hormonal Response

Resistance Exercise (RE) is a widely practiced activity both in leisure time and in training periods for competitive athletes. Recent advanced in molecular biology and muscle physiology has elucidated some of the mechanisms that regulate muscle growth. However, these molecular advances require application in acute program variables of RE. Therefore, we present an updated paradigm of resistance exercise variables and the effect manipulating these has on signalling pathways and hormonal response to optimise RE adaptations. We herein explore the effect of altering (i) choice of exercise; (ii) order of exercises performed; (iii) load (weight/resistance); (iv) volume (i.e. repetitions x sets x load) and (v) rest period between sets. Manipulating these variables has a consequential effect on signalling pathways, hormone response and neural adaptations that may influence protein synthesis and therefore gradual protein accretion leading to increased muscle size and strength.
Anthropometry of Saudi neonates

In the Eastern Province of Saudi Arabia 1094 Saudi neonates were examined anthropometrically. The mean birthweight of term babies (≥ 37-42 weeks gestation) was 3.24 kg (SD 0.46 kg and mean length, mean head and mean chest circumference of this group was 49.21 cm (SD 2.4 cm), 33.94 cm (SD 1.5 cm) and 33.18 cm (SD 1.8 cm) respectively. Male babies (3.24 kg, SD 5.3 kg) were significantly heavier than female infants (3.18 kg, SD 4.5 kg) (p<0.005). Simple correlation coefficients (r) of birthweight with length (0.721), head circumference (0.718) and chest circumference (0.784) of the baby were impressive and significantly related
Medicare Part D Prescription Drug Plans: The Marketplace in 2013 and Key Trends, 2006-2013

Since 2006, Medicare beneficiaries have had access to prescription drug coverage offered by private plans, either stand-alone prescription drug plans (PDPs) or Medicare Advantage prescription drug plans (MA-PD plans). In 2013, more than 35 million Medicare beneficiaries are enrolled in Medicare drug plans, including 22.5 million in PDPs and 12.8 million in MA-PD plans; about 11 million Part D enrollees are receiving extra help through the Part D Low-Income Subsidy (LIS) program to pay their drug plan premiums and cost sharing. Part D has evolved since its inception in 2006 due to changes in the private plan marketplace and the regulations that govern the program. This report presents findings from an analysis of the Medicare Part D marketplace in 2013 and changes in drug coverage and costs since 2006.
Periodontally accelerated osteogenic orthodontics

This case report demonstrates an orthodontic method that offers short treatment time and the ability to simultaneously reshape and increase the buccolingual thickness of the supporting alveolar bone. A 23-year-old female with Angle′s Class I moderately to severely crowded malocclusion with periodontal pocket with 31 and reduced thickness of the buccal cortical plate of lower anteriors, requested shortened orthodontic treatment time. This surgery technique included buccal full-thickness flaps, selective partial decortication of the cortical plates, concomitant bone grafting/augmentation, and primary flap closure. Following the surgery, orthodontic adjustments were made approximately every 2 weeks. From bracketing to debracketing, the case was completed in approximately 7 months and 3 weeks. Posttreatment evaluation of patient revealed good results. Preexisting thin labial bony cortical plate with lower anteriors was covered. This finding suggests credence to the incorporation of the bone augmentation procedure into the corticotomy surgery because this made it possible to complete the orthodontic treatment with a more intact periodontium. The rapid expansive tooth movements with no significant apical root resorption may be attributed to the osteoclastic or catabolic phase of the regional acceleratory phenomenon.
Human Homeostatic Control Matrix in Norm

We undertook our research to study and systemize the relationship between hemodynamics and biochemical parameters of arterial and venous blood in healthy people. Hemodynamic and biochemical characteristics were obtained through a probe by using catheterization in various vascular areas (aorta, brain, heart, lungs, and liver). Correlation and factor analyses were conducted to study the relationship between the obtained characteristics of the regional and systemic blood flow. Due to the nature of the correlation analysis, the significant (p<0.05) relation signs (+, 0, -) without regard to their power were considered. The obtained results suggested that there are sets of both intra-organ and system regulatory relationships between metabolic and hemodynamic characteristics. The complex of relationships among the studied parameters makes it possible to maintain the homeostatic equilibrium in the body. The psychophysiological control system includes the subsystems we described: 1) the cardiac-hepatic-pulmonary complex having properties of the metabolic and hemodynamic information field providing biological stability of the homeostasis; any significant imbalance of its elements triggers afferent information flows actualizing an afferent synthesis; 2) the mind forming gradient patterns of targeted behavior to eliminate metabolic imbalance, to achieve goals both as coded biological parameters and as the highest forms of behavior, to reach the ultimate goal: parametric, homeostatic equilibrium in the “biosphere” of the human body. By using the results of our research and the complex of dynamic relationships in human homeostasis, we built a homeostatic control matrix (HCM). (Int J Biomed. 2016;6(3):184-189. ).