Miracle-dz/UniFAR-FTUs huggingface dataset:
Influence of gender of classroom occupants on indoor air quality

Teachers and students spend a lot of time in the classrooms. It is therefore important to have a good indoor air quality.A cross sectional survey was conducted to characterize the indoor air quality (IAQ) in schools and its relationship with gender of the occupantsas well as its influence on the development of symptoms of allergic conjunctivitis on the teachers who attended these classrooms. Concentrations of total volatile organic compounds (TVOCs), carbon dioxide and temperature were assessed in four girls’ and three boys’ secondary schools in Nakuru, Kenya. The results indicate that the concentrations of carbon dioxide(p=0.043) and TVOCs (p=0.048) were significantly higher in girls’ classrooms than in the boys’ classrooms.There was an association between the gender of classroom occupants and development of symptoms of allergic conjunctivitis among the teachers who taught in those classrooms (χ 2 =5.145; p=0.023). This study concludes that the gender of the classroom occupants influences the indoor air quality of the classroom. It recommends that teachers and students should be trained on the importance of opening windows
The Effect of Islamic Work Ethics on Job Satisfaction, Organizational Commitment, Turnover Intention, and Innovation Capability

This study aims to examine the effect of Islamic Work Ethics on job satisfaction, organizational commitment, turnover intention and innovation capability of employees. Data obtained from the questionnaires distributed to 172 employees who worked in a leading Islamic bank in Indonesia and interviewed several employees to strengthen the analysis. Data was performed by descriptive analysis and partial least squares. The results indicates that Islamic Work Ethics significantly shape job satisfaction, organizational commitment, turnover intention, and innovation capability.This research can be useful for Islamic Banks to improve the management policy to Islamic Work Ethics in their organization culture.
Novel Chiral Chalcone Analogs that Induce M Phase Arrest and Apoptosis in HeLa Cells

We identified two chiral chalcone analogs CCL360 and CCL361 from the Chiba Chemical Library, which exhibit antiproliferative effects on human cancer cells. Flow cytometry analyses revealed that HeLa and Vero cells treated with CCL360 and CCL361 had higher populations of cells in the G2/M phase than untreated cells. Docking studies suggested that the R-isomer of CCL361 binds to the taxol binding domain (TBD) of β-tubulin, and the S-isomers of CCL360 and CCL361 bind to β-tubulin at the colchicine binding domain and the TBD. Further investigations using a fluorescent ubiquitination-based cell cycle indicator system revealed that the two compounds caused cell cycle arrest (in the M phase) and apoptosis only in HeLa cells. In non-cancerous Vero cells, however, CCL360 and CCL361 prolonged the G2/M phase without causing apoptosis. Although increased expression levels of p53 and p21 were observed in all CCL360/361-treated cells, only HeLa cells exhibited increased levels of cleaved poly (ADP-ribose) polymerases and apoptosis. Increases in G2/M phase populations in CCL360/361-treated cells are likely caused by increases in p-histone H3 (at Ser10) and Cyclin B1 levels. Furthermore, CCL360/361-treated HeLa cells exhibited phosphorylation of p-Plk1 (at Thr210) and dephosphorylation of p-Cdc2 (at Tyr15); these changes were not evident in CCL360/361-treated Vero cells, suggesting that the link between p53 and Plk1 in HeLa cells was likely compromised. Our study indicates that CCL360 and CCL361 are microtubule-targeting agents that can be used as lead compounds for developing novel anticancer drugs. Citation: Chen W, Yi R, Vahed M, Ohno Y, Tian Z, et al. (2019) Novel Chiral Chalcone Analogs that Induce M Phase Arrest and Apoptosis in HeLa Cells. Med Chem (Los Angeles) 9: 74-82. Med Chem (Los Angeles), an open access journal ISSN: 2161-0444 Volume 9(6): 74-82 (2019) 75 screening the CCL and were manufactured in our laboratory. Stock solutions (20 mM) of CCL360 and CCL361 were prepared in dimethyl sulfoxide (DMSO, Wako).
The Incentive Effects of Uncertainty in Tournaments

Employees are exposed to different sources of uncertainty when competing in tournaments. First, they face the outcome risk of winning or losing. Second, they face prize risk in promotion tournaments due to the stochastic option value of future promotion possibilities. In addition, employees face strategic uncertainty, since they compete against a performance standard that is endogenously determined by the effort of their opponent. This paper investigates empirically whether and how these sources of uncertainty affect incentives to provide effort. In the absence of strategic uncertainty, we find that outcome risk strongly increases average effort, while prize risk does not affect effort on average. Averages hide substantial variation in individual responses to outcome and prize risk that depend on gender as well as on secondand thirdorder risk attitudes. We also find that agents reduce effort in response to strategic uncertainty, particularly in the presence of outcome or prize risk. JEL codes: C72, C91, D81, D83, J33, M12, M51, M52
Overcoming the Fundamental Limit of Two-Photon Microscopy With Non-Degenerate Excitation

We use non-degenerate two-photon excitation where the two excitation beams are displaced in space outside the focal volume to increase the signal-to-background ratio (SBR), overcoming the fundamental penetration depth limit of conventional two-photon microscopy. © 2020 The Author(s) OCIS codes: (180.0180) Microscopy; (180.2520) Fluorescence microscopy; (180.4315) Nonlinear microscopy.
Transcriptome profiling of fetal Klinefelter testis tissue reveals a possible involvement of long non-coding RNAs in gonocyte maturation

In humans, the most common sex chromosomal disorder is Klinefelter syndrome (KS), caused by the presence of one or more extra X-chromosomes. KS patients display a varying adult phenotype but usually present with azoospermia due to testicular degeneration, which accelerates at puberty. The timing of the germ cell loss and whether it is caused by dysgenetic fetal development of the testes is not known. We investigated eight fetal KS testes and found a marked reduction in MAGE-A4-positive pre-spermatogonia compared with testes from 15 age-matched controls, indicating a failure of the gonocytes to differentiate into pre-spermatogonia. Transcriptome analysis by RNA-sequencing of formalin-fixed, paraffin-embedded testes originating from four fetal KS and five age-matched controls revealed 211 differentially expressed transcripts in the fetal KS testis. We found a significant enrichment of upregulated X-chromosomal transcripts and validated the expression of the pseudoautosomal region 1 (PAR1) gene, AKAP17A. Moreover, we found enrichment of long non-coding RNAs in the KS testes (e.g. LINC01569 and RP11-485F13.1). In conclusion, our data indicate that the testicular phenotype observed among adult men with KS is initiated already in fetal life by failure of the gonocyte differentiation into pre-spermatogonia, which could be due to aberrant expression of long non-coding RNAs.
PROVISION OF GREEN PRACTICES AMONGST HOMESTAY OPERATORS IN KELANTAN

This paper reports on the initial findings on environmental decision-making in the context of Malaysian small service accommodation called Homestay. The study was conducted in Kelantan and involved registered Homestay operators whereby the list was obtained from the Ministry of Tourism and Cultural, Malaysia. In order to determine the main activity of green practices by the Homestay operators in Kelantan, 108 questionnaires have been distributed through the implementation of purposive sampling method. Descriptive analysis was applied and it can be concluded that there is certain application of green practices in these small service accommodations.
Hemodynamic Stability, Patient Acceptance and Cost of Intravenous Propofol and Inhalational Sevoflurane for Induction of Anaesthesia: A Prospective, Randomized Comparative Study

Introduction The effects of an anesthetic agent on the hemodynamic stability are of prime importance in patients with compromised hemodynamics. Although comparative studies of sevoflurane and propofol are reported, most of these are aimed to assess maintenance and early postoperative recovery. There are very few studies on hemodynamic changes occurring with these two agents. This study compares the hemodynamic stability, patient acceptance, and cost of intravenous (IV) propofol versus inhalational (IH) sevoflurane for the induction of anesthesia. Methods This prospective, randomized comparative study was conducted among 80 patients with American Society of Anaesthesiologists (ASA) grade-I requiring general anesthesia (GA) for elective surgical procedures. The study was approved by the institutional ethics committee and was conducted as per the principles of the Declaration of Helsinki and Good Clinical Practice (GCP) guidelines. Enrolled patients were randomized to receive either intravenous (IV) propofol 2 mg/kg (n=40) or gradual inhalational (IH) induction with sevoflurane (n=40). All patients were maintained with sevoflurane 2% in 67% nitrous oxide (N2O) and O2. Hemodynamic parameters like pulse rate and mean arterial pressure (MAP) were monitored every minute up to five minutes. Patients' acceptance was assessed on a 10-item questionnaire, and the cost of anesthesia was assessed based on the anesthetic requirement. The hemodynamic parameters were compared between the two groups using two-way repeat-measures ANOVA. The incidence of hypotension was compared using Fischer’s test. Results The two groups were similar at baseline with respect to the demography and other baseline characteristics. There was greater (p<0.05) fall in MAP with propofol induction (28.48%) compared to sevoflurane (14.61%). Greater reduction in pulse rate (p<0.05) with sevoflurane (9.18) induction was observed compared to propofol (5.28). Patient acceptance for both drugs was similar (p>0.05). Although sevoflurane was unpleasant, propofol injection was painful. Ninety percent of patients preferred propofol for repeat anesthesia as against 85% of patients with sevoflurane. Considering the quantity of anesthetic consumed and the unit cost, propofol was more costly as compared to sevoflurane. Conclusion Sevoflurane maintains better hemodynamic stability compared to propofol, and patient acceptance of both drugs is similar. Induction with sevoflurane was found to be cheaper as compared to propofol induction.
Proposed Technique for Securing Critical Data Over Cloud

: Cloud computing has emerged as a new computing platform where users are able to use services provided by cloud service providers on basis of pay per use model. The services can vary from using infrastructure and platform or software as a service. From the origination of Cloud Computing technology, the major concern for the users is to secure their data being stored over cloud storage servers. Although there are different cryptographic algorithms being implemented over cloud to secure user’s data but still there are instances of unauthorized intrusions emerging over cloud platform. To tackle the situation of securing user’s cloud based data or files a new approach is being proposed here in this paper. Further, this paper also focuses on securing cloud based data from malicious insider attacks with the help of the proposed technique.
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The aim of the present paper is to review the literature on the separation of the ewe-lamb bond and its effects on behaviour, vocalisations and physiological indicators as mechanisms of acute stress in ewes and lambs. In all mammal species mothers constitute the most important social contact for their young during the first months of life, as they facilitate the acquisition of information on the physical and social environments. In sheep, soon after parturition, a mutual, lasting ewe-lamb bond is established. Mothers can identify their young through the use of different sensory modalities (olfaction, vision, hearing and direct contact), but the proper expression of adequate maternal behaviour is made more difficult by modern livestock-handling systems that in order to increase fecundity intensify demands on the mothering ability of ewes. In conventional dairy sheep production systems, weaning lambs are suckled by either their dams or surrogates. When the ewe-lamb bond is broken, frustration arising from maternal feeding deprivation and the absence of maternal care alter endocrine and behavioural responses and reduce growth, suggesting emotional disturbances in the lambs. Many authors have indicated that stressor factors on the farm, such as isolation or separation, alter the indexes of animal welfare, including hormonal, haematological and biochemical parameters. In the case of sheep, the fact that they are gregarious animals makes them highly sensitive to the stress of separation from the flock. The measurement of plasma constituents in blood samples can provide information about the stress that animals suffer during various handling operations. On the other hand, weaning, particularly at a young age, is also associated with perturbed growth rates and an increased susceptibility to disease. Disruption of the maternal relationship, therefore, is at least a transient source of poor welfare for lambs, and may disturb the acquisition of social and survival-related behaviours. The lambs manifested strong vocal responses when these periods of temporary separation were first imposed, but eventually became habituated to the procedure and then showed little response compared to lambs that had not experienced such temporary separations. The close mother-offspring relationship established during the first few minutes of life after birth is very important for the development and survival of newborns in practically all species, including sheep. To improve our understanding of the consequences of breaking the ewe-lamb bond, factors that contribute to the establishment of the motheryoung relationship are discussed in the first part of this review. The second part deals specifically with the effects of separation on the ewe-lamb bond; namely, variables and measurements of behaviour, vocalisations, and blood profiles.
Inferring soil moisture memory from streamflow

14 Soil moisture is known for its integrative behavior and resulting memory characteristics. 15 Soil moisture anomalies can persist for weeks or even months into the future, making 16 initial soil moisture a potentially important contributor to skill in weather forecasting. 17 A major difficulty when investigating soil moisture and its memory using observations is 18 the sparse availability of long-term measurements and their limited spatial representa19 tiveness. In contrast, there is an abundance of long-term streamflow measurements for 20 catchments of various sizes across the world. We investigate in this study whether such 21 streamflow measurements can be used to infer and characterize soil moisture memory 22 in respective catchments. Our approach uses a simple water balance model in which 23 evapotranspiration and runoff ratios are expressed as simple functions of soil moisture; 24 optimized functions for the model are determined using streamflow observations, and 25 the optimized model in turn provides information on soil moisture memory on the catch26 ment scale. The validity of the approach is demonstrated with data from three heavily 27 monitored catchments. The approach is then applied to streamflow data in several 28 small catchments across Switzerland to obtain a spatially distributed description of 29 soil moisture memory and to show how memory varies, for example, with altitude and 30 topography. 31
The role of theory in ethnographic research

■ Scholars, including urban poverty researchers, have not seriously debated the important issues that Loïc Wacquant raised in his controversial review of books by Elijah Anderson, Mitchell Duneier, and Katherine Newman concerning the disconnect between theory and ethnographic research. Despite the tone of Wacquant’s review, we feel that he made a contribution in raising important issues about the role of theory in ethnography. The responses to his review that address this issue, especially those by Anderson and Duneier, are also important because they help to broaden our understanding of how theory is used in ethnographic research. What we take from this exchange is that good ethnography is theory driven, and is likely to be much more reflective of inductive theoretical insights than those that are purely deductive. Moreover, we show that in some ethnographic studies the theoretical insights are neither strictly deductive nor inductive, but represent a combination of both.
Knowledge, Attitudes, and Perception of Malaria Infection among Pregnant Women in a Semi-Urban Setting in Nigeria

Background: Malaria infection during pregnancy is a major public health problem in tropical and subtropical regions throughout the world. The burden of malaria infection during pregnancy is caused mainly by Plasmodium falciparum, the most common malaria species in Africa. This study is aimed at assessing the knowledge, attitudes and perception of malaria among the pregnant women attending the antenatal clinic in general hospital Gboko, Gboko Local Government, Benue State. Method: This research is an ex post facto cross-sectional study that focuses on only pregnant women. Structured questionnaires were developed, validated and administered to the respondents and information on age, occupation, marital status, number of previous pregnancies, number of children, mosquito control methods and educational levels were obtained. Data analysis was done using the Statistical Package for Social Science (SPSS) version 22. Descriptive statistics such as frequencies and cross-tabulations, percentages and mean were used to describe the data. Results:There were 144 participants of which majority, 62.5% were in the age group 20 – 30 years. The majority were secundigravid (79.2%). All have ever heard about malaria, chose IPT as an antimalarial drug for pregnant women, have undergone malaria test in the last 6 months and they all sleep under mosquito nets. They chose headache, 54.2% and fever, 39.6% as major symptoms of malaria. 97.9% were tested positive for malaria in the last 6 months. The majority (97.9%) knew that malaria has a cure, 97.9% knew that it is impossible to cure malaria spiritually, 97.9% knew that antibiotics or antiretroviral therapy cannot cure malaria while 85.4% believed that personal hygiene would reduce malaria. None of the respondents had a university education, yet they had very sound knowledge, attitudes, and perception of Malaria in pregnancy. Conclusion:This study found a very good knowledge, attitude and perception of malaria infection among pregnant women in Gboko, Benue state but the proportion of the women diagnosed positive to malaria parasite within six months to this study was very high (more than 95%). Therefore, further investigation is needed to unravel the causes of the high prevalence of malaria infection in this area.
Model of Knowledge for Students Prospective

Various attempts have been made to make teachers a profession that is on par with other professions in the world. LPTK as a teacher producing institution is the party responsible for preparing teacher candidates. This article aims to introduce a learning model that can improve the professionalism of prospective teacher students. The learning model developed refers to the criteria of the model developed by Joyce & Weil. AJARI learning model is a learning model that in learning has natural characteristics, describe / articulation, reflection and my ideas. In this learning model students are expected to experience the experience of a scientist at the same time get the opportunity to design learning according to their creative ideas. Through this learning model, it is expected to be a unique learning model for prospective teacher students.
The Effect of Psycho- Educational Intervention on Knowledge, Coping and Burden among Caregivers of Person Substance Use Disorders

Substance use disorder is a multidimensional problem which threatens the quality of life not only substance abusers but also the family members who live with them. Most of the time a member of the family assumes the role of caregiver and he or she is most burdened from this process. Considering that it is necessary to appropriately provide the training to caregivers and evaluate their needs for caregiving. Aim of the study: The aim of the present study was to evaluate the effect of a psych educational intervention on knowledge, coping and burden among caregivers of persons with substance use disorders . Subjects and Method: Study design: The study was followed a quasi-experimental design. Setting: The study was conducted at the addiction outpatient's clinic in Tanta Mental Health Hospital; the hospital is operated by the Ministry of Health and Population. Subjects: The subjects of this study were 40 caregivers of persons with substance use disorders chosen by a convenience sample. Tools of data collection: Three tools were used for this study: Tool I : Structured substance use disorders knowledge questionnaire, Tool II :-Family crisis oriented personal evaluation scale (F.COPES) and Tool III :The Zarit Burden caregiver scale Results: there was an improvement of the mean of the total score of caregiver's' knowledge and Family crisis oriented personal evaluation scale (F.COPES ) and there was a reduction of the mean of the total score of Zarit Burden Caregiver. Conclusion:-It can be concluded that psycho-educational intervention was effective in improving knowledge, coping and reducing caregivers' burden. Recommendations: Based on the results of this study it is recommend that identifying educational needs and implementing supportive and coping interventions for caregivers should be an integral part in recovery process