Miracle-dz/UniFAR-FTUs huggingface dataset:
Perceived emotional intelligence and the psychological well-being of university students depending on the practice of physical activity

El objetivo principal fue analizar la inteligencia emocional percibida y el bienestar psicologico de los estudiantes universitarios en funcion de la practica de actividad fisica. Se utilizo una muestra de 1008 estudiantes de una universidad publica andaluza con edades comprendidas entre los 17 y los 30 anos, de los cuales 414 eran fisicamente activos y 594 insuficientemente activos. Se emplearon diferentes cuestionarios para evaluar la actividad fisica habitual, la inteligencia emocional percibida y el bienestar psicologico. El analisis de correlaciones mostro que los constructos de claridad y reparacion emocional correlacionaban positiva y significativamente con la autoestima y satisfaccion con la vida. Se encontraron diferencias significativas entre los universitarios fisicamente activos y los que no en todas las variables, salvo en la atencion emocional. Los alumnos fisicamente activos mostraron puntuaciones mas elevadas en las variables que median el bienestar (autoestima y satisfaccion con la vida), en la claridad y reparacion emocional. Los resultados se discuten en relacion a la promocion de la actividad fisica como favorecedora del bienestar y la inteligencia emocional percibida en el alumnado universitario.
Removing Barriers to Service Delivery: An Outcome Evaluation of a ‘Remodelled’ Foster Care Programme1

Yvonne Unrau, Michael Wells and Mary Ann Hartnett describe a US family-centred, needs-based foster care programme named Promise and present evaluation findings based on a comparison group design evaluation. Promise allowed for greater discretion among line-level workers to meet the unique service needs of families served, promoted greater team-oriented communication and involved more foster family involvement than the comparison group. An initial statistical comparison revealed that foster children in the Promise group (n = 380) experienced greater stability in their caseworker assignment and, to a lesser degree, greater placement stability over a 15-month period when compared to foster children served under the conventional model (n = 436). However, only the caseworker continuity effect remained when further analysis was undertaken. Similar rates of permanency achievement were reported for both models. Implications for foster care policy, practice and research are presented.
Flax treatment with strategic enzyme combinations: Effect on fiber fineness and mechanical properties of composites

The application of natural fibers as reinforcement material in composites can make an important contribution toward a more sustainable bio-based economy. To use these natural fibers, they need to be released from the stem. Traditionally, this is realized by dew retting. However, there are some disadvantages to this retting procedure. Due to changing weather conditions, it is quite difficult to guarantee a good and consistent fiber quality. Replacing the traditional retting process by a biocatalytic process may resolve these issues through application of a combination of pectinase and hemicellulase activities. In this context, several strategic pectinase and hemicellulase activities were blended. Flax fiber fineness and mechanical properties of resulting unidirectional fiber–epoxy composites were studied after treatment of flax stems with these strategic enzyme combinations. Characterization of fiber fineness showed a higher percentage of fiber widths smaller than 100 µm after combined treatment with two enzymes (44.7%), and the percentage was even higher after some combinations with three enzymes (51.2%). Assessment of mechanical properties of composites showed no significant differences in tensile or transverse properties for combined enzymatic treatments. Fiber properties were back-calculated from unidirectional flax fiber–epoxy composites and a Young’s modulus of 88 GPa and a tensile strength of 865 MPa were observed. Enzymatic extraction resulted in the achievement of similar results as dew retting concerning mechanical composite performance and fiber fineness.
Clinical Characteristics and Outcome of Treatment of Brazilian Women with Breast Cancer Treated at Public and Private Institutions – The AMAZONE Project of the Brazilian Breast Cancer Study Group (GBECAM).

Introduction: With close to 50,000 new cases/year, breast cancer is the most common cancer among Brazilian women. There are few data regarding the clinical presentation, treatment and outcome of this population.Methods: The Brazilian Breast Cancer Study Group (GBECAM) collected data from 28 cancer centers distributed throughout the country on 1-) clinical characteristics, 2-) type of treatment received and 3-) survival curves of 4,912 Brazilian women presenting with breast cancer and treated at public (Pu), and private (Pr) institutions in the years 2001(N=2,198) and 2006 (N=2,714). Results:1-) Mean age at diagnosis was 59.3 (median=58), with 25.4% below age 50. Stage 0 was seen in 2.8%, Stage I in 20.2%, Stage II in 46.8%, Stage III in 24.6% and Stage IV in 5.5%. Clinical Stage III+IV was seen in 36.9% of pts in Pu, and only 16.2% in Pr institutions. Hormone Receptors were positive in 69.9% of pts; HER2 was overexpressed/amplified in 20.3%; 19.1% of the cases were triple-negative. 2-) Neoadjuvant chemotherapy (CT) was done in 26.5% of cases in Pu and only 11% of Pr pts. Breast-conserving surgery was performed in 40.9% of Pu and 51.7% of Pr pts. Sentinel node biopsy was done in 15.9% of Pu and 25.9% of Pr pts. Adjuvant therapy was done in 88.2% of the cases. Adjuvant CMF was done in 31.4% of Pu and 15.8% of Pr pts; anthracycline plus taxane was used in 9.2% of Pu and 23.5% of Pr pts. In the cohort of 2006, adjuvant trastuzumab was given to 56.2% of Pr but only 6.6% of Pu pts. Adjuvant hormonal therapy consisted of tamoxifen (TAM) in 86.6%, aromatase inhibitors (AI) in 6.3% and sequential Tam/AI in 6.6% of pts. Adjuvant radiotherapy was given to 76% of the cases. 3-) Survival was studied for all patients of the 2001 cohort. Disease-free survival (DFS) at 5 years was 78% for Pr vs 72% for Pu institutions. Overal survival (OS) at 5 years was 97% in Pr vs 88% in Pu institutions. When analyzed by stage, there was no apparent difference when pts with stage I or II were treated in Pr or Pu institutions. In stage III, however, DFS was 61% in Pr vs 47% in Pu institutions. OS in Stage III disease was 95% for Pr vs 65% in Pu institutions.Conclusions: Our data suggest that pts with breast cancer in Brazil present with more advanced stages in Pu institutions. These pts are more likely to receive neoadjuvant CT and undergo total mastectomy. These pts receive more CMF and less anthracycline/taxane combinations as adjuvant CT. Patients with Stage III disease treated in Pu institutions have inferior DFS and OS compared to similar pts treated in Pr institutions. Citation Information: Cancer Res 2009;69(24 Suppl):Abstract nr 3082.
Inherited Thrombophilia Polymorphisms and Pregnancy Outcomes in Nulliparous Women

OBJECTIVE: To estimate the association between five commonly inherited thrombophilia polymorphisms and adverse pregnancy outcomes in women who had no prior history of adverse pregnancy outcomes or personal or family history of venous thromboembolism. METHODS: Healthy nulliparous women (n=2,034) were recruited to this prospective cohort study before 22 weeks of gestation. Genotyping for factor V Leiden, prothrombin gene mutation, methylenetetrahydrofolate reductase enzyme (MTHFR) C677T, MTHFR A1298C, and thrombomodulin polymorphism was performed. Clinicians caring for women were blinded to the results of thrombophilia tests. The primary composite outcome was the development of severe preeclampsia, fetal growth restriction, placental abruption, stillbirth, or neonatal death. RESULTS: Complete molecular results and pregnancy outcome data were available in 1,707 women. These complications were experienced by 136 women (8.0%). Multivariable logistic regression demonstrated two statistically significant findings. Women who carried the prothrombin gene mutation had an odds ratio of 3.58 (95% confidence interval [CI] 1.20–10.61, P=.02) for the development of the composite primary outcome. Homozygous carriers of the MTHFR 1298 polymorphism had an odds ratio of 0.26 (95% CI 0.08–0.86, P=.03). None of the other polymorphisms studied showed a significant association with the development of the primary outcome in this cohort of women. CONCLUSION: Prothrombin gene mutation confers an increased risk for the development of adverse pregnancy outcomes in otherwise asymptomatic, nulliparous women, whereas homozygosity for MTHFR 1298 may protect against these complications. The majority of asymptomatic women who carry an inherited thrombophilia polymorphism have a successful pregnancy outcome. LEVEL OF EVIDENCE: II
Effect of long-term administration of amiodarone on rat lung and the possible protective role of vitamin E: a histological and immunohistochemical study

Introduction Amiodarone is gaining support as a first-line antiarrhythmic drug despite its potentially fatal pulmonary complications involving inflammation and fibrosis. Objective This study was undertaken to investigate the effect of long-term amiodarone administration and withdrawal on the histological structure of rat lung. In addition, the possible protective role of vitamin E supplementation was studied. Materials and methods This study was carried out on 36 adult male albino rats, which were divided into four groups: group I, which was considered as control; group II (amiodarone-treated group), which received amiodarone orally in a daily dose of 30 mg/kg body weight for 12 weeks; group III (withdrawal group), which received the same dose of amiodarone for 12 weeks and were sacrificed 6 weeks after withdrawal of the drug; and group IV (protected group), which received vitamin E orally in a daily dose of 100 mg/kg body weight simultaneously with amiodarone for 12 weeks. At the time of sacrifice, the lungs were dissected and tissue samples were processed for both light and electron microscopic studies. Immuohistochemical study using anti-CD68 for showing alveolar macrophages was also performed and the number of positively stained cells was morphometrically estimated and statistically analyzed. Results Administration of amiodarone alone showed an alteration in the lung architecture in the form of collapsed alveoli with evident proliferation and vacuolation of pneumocytes type II. Thickening of interalveolar septa, cellular infiltration, and collagen deposition associated with an increased number of macrophages as proved by the morphometric study were demonstrated. Intrabronchial cellular debris and vascular congestion were also observed. Coadministration of amiodarone with vitamin E showed a considerable degree of preservation of the pulmonary alveolar architecture; however, a mild improvement in the lung injury was observed in animals after amiodarone withdrawal. The alveoli were lined mainly by vacuolated pneumocytes type II with moderately thickened interalveolar septa. Conclusion From this study it could be concluded that prolonged administration of amiodarone in rats can induce severe lung damage. Withdrawal of the drug showed little improvement of this harmful effect but concomitant administration of vitamin E effectively protected the lung tissue. In addition, the increased number of alveolar macrophages associated with amiodarone administration has supported the concept that these cells may play a role in the pathogenesis of lung injury caused by amiodarone.
Predictors of adult men's gender-role conflict : race, class, unemployment, age, instrumentality-expressiveness, and personal strain

Gender-role conflict exists when socialized gender roles result in personal restriction, devaluation, or violation of others or self. This research assesses the ways in which 13 demographic, psychological, and strain variables predict adult men's gender-role conflict. It was hypothesized that these variables would differentially predict four patterns of gender-role conflict that have been documented in earlier research (O'Neil, Helms, Gable, David, & Wfightsman, 1986). Men (N ffi 134) of different ages, races, classes, personality characteristics and work statuses were assessed with the Gender Role Conflict Scale, the Personal Strain Questionnaire, and the Personal Attributes Questionnaire. Two meaningful and independent male constellations linking 9 of the predictor variables with 3 patterns of gender-role conflict accounted for 88% of the variation in gender-role conflict. Methodological limitations and future research are discussed. Gender-role conflict is defined as a psychological state in which socialized gender roles have negative consequences on a person or on others. The ultimate outcome of this kind of conflict is a restriction of the human potential of the person experiencing the conflict or a restriction of another's potential. Gender-role conflict occurs when rigid, sexist, or restrictive gender roles result in personal restriction, devaluation, or violation of others or self (O'Neil, 1990). Gender-role conflict is important because men's gender roles have been associated with rape (Russell, 1984), family violence (Finn, 1986), and child sexual abuse (Finkelhor, 1984). Limited research exists on correlates of men's gender-role conflict and their impact on men's and women's lives. In the 1980s, numerous measures of gender-role conflict and related concepts were developed. Researchers developed instruments measuring the macho personality (Mosher & Sirkin, 1984), gender-role conflict (O'Neil, Helms, Gable, David, & Wrightsman, 1986), gender-role stress (Eisler & Skidmore, 1987; Eisler, Skidmore, & Ward, 1988), masculine roles (Snell, 1986; Snell, Belk, & Hawkins, 1986), and masculine attitudes (Brannon & Juni, 1984; Downs & Engelson, 1982). These measures give scientific respectability to the study of genderrole conflict in men because empirical data now document that men experience gender-role conflict. Men's studies and
Study of Differentiated Beta-Human Chorionic Gonadotropin Serum (BhCG), Progesterone and CA-125 in Patients with Tubal Ectopic Pregnancy

"Ectopic pregnancy (EP) is 6-10% of all pregnancy related deaths. The incidence of EP is 1-2% in the developed countries. In the present study we evaluated the serum BhCG, progesterone and CA-125 level in the efficacy of methotrexate for treatment of ectopic tubal pregnancy. Over a period of two years, 61 patients with the diagnosis of ectopic pregnancy included in study. 30 cases were in methotrexate (MTX) treatment group and 31 cases in surgical treatment group. Sera of samples were assayed for BhCG, progesterone and CA-125. Analyses were performed using SPSS version 16 computer software. T-test and chi square, Roc analysis was used for Sensitivity and specifity. Mean of baseline BhCG level at initial presentation was 439±363 in MTX group and 1027±722 in surgical treatment group; These levels in two groups were significantly different (p=0.001). Mean of initial serum progesterone level was significantly higher in surgical treatment group than medical treatment group (p<0.006). In addition, no statistically difference was observed in CA-125 between two groups (p<0.671). Finding of this study showed that pretreatment serum BhCG and progesterone level had meaningful relation with the efficacy of medical treatment of ectopic pregnancy; Also in this study CA-125 was not a predictor of MTX treatment. "
Pharmacoeconomic studies of bypassing agents in mild-to- moderate bleeding episodes in patients with hemophilia and inhibitors: a critical appraisal

The development of neutralizing antibodies against factor VIII and IX complicates the clinical management of patients with hemophilia, and adds significant costs to their treatment. For this reason, several formal economic analysis have been performed comparing treatment of mild and moderate bleeding episodes in these patients in an effort to determine whether one of the two available bypassing agents would be cost-effective compared with the other. Here we review and discuss the available evidence about the economic aspects of the alternatives for on-demand treatment of mild and moderate bleeding episodes for hemophilia patients with inhibitors.
PRECANCEROUS AND CANCEROUS LESIONS OF CERVIX DIAGNOSED BY PAP'S SMEAR - A HOSPITAL BASED STUDY

BACKGROUND: Cervical intra-epithelial neoplasia (CIN) and cervical cancer remain important health problems for women worldwide. It is largely a preventable disease that is characterized by a long lead time. The objective of this study was to determine the frequency of precancerous lesions of cervix by Pap smear screening. METHODS: A retrospective hospital based study was conducted at Department of Pathology, in a Tertiary Care Institute and associated hospital, Bhopal. Data was collected from the records of Pap's smear testing done on 388 patients in years 2011 & 2012. Analysis was done by entering data in SPSS software and Chi-square test was applied to find statistical significance. RESULTS: Most common lesions on Pap's smear was Low grade squamous intraepithelial lesion (LSIL) in 104 (26.8%) of cases and High grade squamous intraepithelial lesion (HSIL) in 15 (3.9%) of cases. 44 (11.3%) were senile Atopic Changes, parasitic Infection in 27 (7%) of cases and 2 (0.5%) were carcinoma cervix cases. All the cervical lesions were most common in age of 31-40 yrs. and were significantly associated with age. CONCLUSIONS: Pap's smear examination information should be spread in community apart from hospitals. Especially the young women should be motivated for regular Pap's smear. Pap's smear is the single most important screening method for early detection of precancerous & cancerous cervical lesions.
A Randomised Comparison of the Supreme Laryngeal Mask Airway with the i-gel During Anaesthesia

Objective: The i-gel and LMA Supreme are second-generation supraglottic airways. We performed a comparison of the two with the primary endpoint of first insertion success by experienced anaesthetists. Methods: With Ethics Committee approval, patients were randomised to insertion of either device. Anaesthesia was maintained with sevoflurane and patients were not paralysed. Data was collected on insertion, oropharyngeal leak pressure, fibreoptic view via both airway and drain tube, adequacy of controlled ventilation, clinicians’ subjective assessments of airway performance and complications at each stage from insertion to the first post-operative day. Results: Data from 97 patients were analysed. The primary outcome was insertion success on first attempt, which was 78% for i-gel and 87% with SLMA (p=0.4). There were no statistically significant differences between the two devices’ performances: >92% overall insertion success, >98% of airways rated “good” after insertion, >90% optimal ventilation, minimal complication rates during insertion, maintenance and removal, and low rates of postoperative sequelae, >90% of which were mild. Both devices performed safely, with no episodes of aspiration or long term sequelae. Conclusions: We have conducted a rigorous comparison of the i-gel and SLMA in a European population receiving sevoflurane anaesthesia, without muscle relaxation. Performance of the two devices is very similar.
Adsorption of lead ion from aqueous solution unto cellulose nanocrystal from cassava peel

Acid hydrolysis was used for the synthesis of cellulose nanocrystal (CNC) from cassava peel (CP). The process was carried out at 45 0 C for 45 min using 64% concentrated sulphuric acid, Pb 2+ was removed from aqueous solution using the synthesized CNC adsorbent. Cassava peel cellulose nanocrystal (CPCNC) was characterised using FT-IR and X-Ray diffraction techniques. The different operational factors were examined to enhance the conditions for optimum adsorption of Pb 2+ . The equilibrium adsorption figures fitted well into both the Freundlich and Langmuir isotherm models, indicating that adsorption was due to the formation of a monolayer adsorption unto a homogenous surface and showed a good relationship between the Pb 2+ and the CPCNC. The separation factor, RL, which is a dimensionless constant ranged between 0.02 and 0.248 and indicated that the adsorption was feasible and favourable. The optimum adsorption capacity was 6.4 mg Pb 2+ /g CNC at 25 o C and pH 6. This study revealed that this novel nanomaterial has an unlimited prospect for effective removal of lead ion from aqueous solution.
Levonorgestrel intrauterine system versus medical therapy for menorrhagia.

BACKGROUND Menorrhagia is a common problem, yet evidence to inform decisions about therapy is limited. In a pragmatic, multicenter, randomized trial, we compared the levonorgestrel-releasing intrauterine system (levonorgestrel-IUS) with usual medical treatment in women with menorrhagia who presented to their primary care providers. METHODS We randomly assigned 571 women with menorrhagia to treatment with levonorgestrel-IUS or usual medical treatment (tranexamic acid, mefenamic acid, combined estrogen-progestogen, or progesterone alone). The primary outcome was the patient-reported score on the Menorrhagia Multi-Attribute Scale (MMAS) (ranging from 0 to 100, with lower scores indicating greater severity), assessed over a 2-year period. Secondary outcomes included general quality-of-life and sexual-activity scores and surgical intervention. RESULTS MMAS scores improved from baseline to 6 months in both the levonorgestrel-IUS group and the usual-treatment group (mean increase, 32.7 and 21.4 points, respectively; P<0.001 for both comparisons). The improvements were maintained over a 2-year period but were significantly greater in the levonorgestrel-IUS group than in the usual-treatment group (mean between-group difference, 13.4 points; 95% confidence interval, 9.9 to 16.9; P<0.001). Improvements in all MMAS domains (practical difficulties, social life, family life, work and daily routine, psychological well-being, and physical health) were significantly greater in the levonorgestrel-IUS group than in the usual-treatment group, and this was also true for seven of the eight quality-of-life domains. At 2 years, more of the women were still using the levonorgestrel-IUS than were undergoing the usual medical treatment (64% vs. 38%, P<0.001). There were no significant between-group differences in the rates of surgical intervention or sexual-activity scores. There were no significant differences in serious adverse events between groups. CONCLUSIONS In women with menorrhagia who presented to primary care providers, the levonorgestrel-IUS was more effective than usual medical treatment in reducing the effect of heavy menstrual bleeding on quality of life. (Funded by the National Institute of Health Research Health Technology Assessment Programme; ECLIPSE Controlled-Trials.com number, ISRCTN86566246.).