Miracle-dz/UniFAR-FTUs huggingface dataset:
Assessing Primary Care Physicians’ Attitudes Towards Adoption of an Electronic Tool to Support Cancer Diagnosis

The objective of this study was to assess Primary Care Physicians’ (PCPs) attitudes towards adoption of the Diagnostic Assessment Program-Electronic Pathway Solution (DAP-EPS), an electronic tool for improving cancer diagnostic processes. The implementation of DAP-EPS is a provincial activity supported by Cancer Care Ontario in collaboration with the Canadian Cancer Society. We conducted an online survey of Ontario PCPs. To guide our study, we used an integrated theoretical framework combining the Technology Acceptance Model and Diffusion of Innovation. Study results suggested a strong influence of perceived usefulness of the DAP-EPS tool on physicians’ attitudes towards adoption of the tool. The results also found that perceived usefulness was more important than perceived ease-of-use within the PCP context. The study revealed that perceived usefulness is the main predictor of the attitude towards adoption of the DAP-EPS tool. The findings also suggested that the management and implementation team should emphasize the usefulness of the DAP-EPS to increase its adoption among PCPs.
Probiotics in acute diarrhea: A randomized control trial

Background: Probiotics have been used for long in the treatment of acute diarrhea although their efficacy has always remains the subject of discussion. Objective: To determine the effect of probiotics in acute diarrhea among the children in rural population. Method: Double-blinded randomized control trial. We included children of age group 6 months - 5 years suffering from acute diarrhea of <48 h and fulfilling the inclusion criteria. All children were given oral rehydration salts (ORS) ad-lib till the resolution of diarrhea and zinc 20 mg/day for 14 days while intervention arm (n=101) were given probiotic sachet twice a day for 7 days containing Streptococcus faecalis 30 million, Clostridium butyricum 2 million, Bacillus mesentericus 1 million, Lactobacillus sporogenes 50 million, control group were given identical placebo apart from ORS and zinc. Duration of diarrhea in both the groups was measured as primary outcome while secondary outcome was to know the days of maximum recovery from diarrhea in both groups. Results: Totally, 207 patients were randomized to control and study group, out of which, 195 completed the study. Out of total 195 patients, 94 (48.2%) patients were treated with standard treatment of diarrhea without probiotics while 101 (51.8%) patients were given probiotics apart from standard treatment of diarrhea. The mean duration of diarrhea was found to be reduced in the study group (4.6 days [2.84-4.776 days]) as compared to control group (5.31 days [5.108-5.512 days]), p<0.001. Conclusion: Probiotics significantly reduced the duration of acute diarrhea in children.
Family Perception in Readiness Accepting Discharge Planning Determined by Nursing Advocacy Program

Introduction: Planning for patients to go home raises the issue of whether the patient is ready to face health problems at home, the lack of a support system becomes a problem especially if the patient as the head of the family needs continuity of care both in the healing process and in maintaining the patient's health status both at home sick or at home. The purpose of this study was to determine how is the Role of Advocacy given by Nurses with Readiness in Receiving Discharge Planning by patients and families. Methods: The cross-sectional correlational study in this study views the patient's family support in readiness to receive the patient's home program on the ward. Sampling 97 respondents with a purposive sample technique. Results: Family perceptions about nurses in the positive category (73.2%). The level of family readiness in accepting return planning in the good category (53.6%), the results of the bivariate analysis using the Spearman rating relate to family perceptions about nurse advocacy with readiness in accepting return planning with a p value of 0.00 <alpha 0.01. Conclusion: Family perceptions about nurse advocacy with home preparation have a strong relationship, so family assistance in nursing care in re-care planning is needed. family perceptions of nurses are needed including nursing actions or other matters relating to care by the family also need to support patient health.
Various aspects of plateletpheresis: Its impact on donor and patients

Background and Aim: Platelet transfusion plays an important role in the treatment of hematological, oncological, surgical, and transplant patients. Aphaeresis technology is widely available in the world and some part of India, but it is new for our region. The present study aims at various aspects of plateletpheresis including donor safety, donor hematological changes following single donor platelet (SDP) donation, quality of product, and impact on patient following SDP transfusion. Materials and Methods: Preprocedural hematological count such as total platelet count (TPC), hemoglobin, red blood cells, and white blood cells count was recorded. All donors were observed for adverse donor reactions. Postdonation (after 30 min) sample was drawn to see the hematological parameters and compared to that of pre donation hematological parameters. Quality control of all SDP products was done. All recipients were observed for any transfusion reactions. Post 24 h transfusion sample was obtained from the SDP recipient and compared to that of pretransfusion sample to see the platelet increment. Results: A total of 135 plateletpheresis procedures were performed on cell separator. SDP was collected from the donors as per standard operating procedure. All donors were observed for adverse donor reaction. We found an adverse event with one donor. There was decrease in mean value of all hematological parameters in the postdonation sample. There was no thrombocytopenia either clinically or from laboratory value. Similar trend was seen with double yield collection. Mean acid citrate dextrose (ACD) used was 328, mean blood volume processed 3385 ml, mean product volume was 249 ml, mean time was 76.8 min during the procedure. Quality control of all SDP products was done. Mean yield was found to be 4.18 ± 0.95 × 1011 per unit. A positive correlation was seen between pre TPC of donor and product yield. Post 24 h transfusion sample was obtained from the SDP recipient and compared to that of pretransfusion sample to see the platelet increment. We observed mean increment of platelet count to be 76.15 × 109/L. Overall therapeutic benefit was observed in all cases. Conclusion: The study found that plateletpheresis procedure is very safe from donor point of view and SDP product is effective from recipient's point of view.
Challenges in Transforming Assessments for 21st Century Skills Development: Lecturers’ Perspective

The primary purpose of an assessment in pedagogy is to provide data and revise planned instructions. As the producers of skilled labour for the private sector, private higher education institutions (PHEIs), need to facilitate the transformation of assessments focused on developing 21st century skills competencies in students. In preparing for Industry 4.0, the private sector in Malaysia is concerned about fresh graduates not being adequately skilled for the workplace. The gap can lead to unemployment and a shortage in skilled labour. This research is designed to understand the challenges in transforming assessments to address the 21st century skills gap. Based on an epistemological belief through a social constructivist interpretive framework, a case study approach is used to co-construct the reality shaped by the course lecturers’ experiences. Based on purposeful sampling, two (2) business lecturers with over five (5) years of teaching experience, and familiar with the diploma standards were selected from the School of Business. Data was collected using semi-structured interviews, document reviews and audiovisual materials. A data analysis strategy of reducing codes to themes and identifying patterned regularities was used to produce a written report. The findings reveal the challenges faced by lecturers in transforming assessments to develop 21st century skills. The recommendation is for assessments to be transformed based on private sector skill needs to keep up with the changing work skills demands of Industry 4.0. Continuous initiatives in shared value partnerships with the private sector will ensure that the development of 21CS remains relevant.
Food safety in the retail environment

Retail establishments have the responsibility to deliver safe food to consumers. This research focuses on food safety in the retail environment from three different perspectives: refrigeration of fruits and vegetables, food handling behavior of produce stockers, and migration of harmful chemicals from packaging into food. The recent information provided gives an updated perspective to food safety issues such as produce refrigeration in retail establishments, food handler behavior, and perfluorinated compound migration in microwave popcorn. Twentyfive open and closed display cases stocked with produce from four retailers in five states of the United States (US) were monitored in eight positions for temperature and relative humidity (RH) conditions. Significant factors were doors, retailer, and sensor positions. Abuse time and variability in temperature and RH conditions were reduced in closed display cases. Employee behavior and food handling practices were observed in a casual way in retail stores in four states of the US over a period of 12 months. Observations were recorded and classified into topics for handwashing, stocking and rotation, handling of fallen produce, display case cleaning, customer behavior, refrigeration and temperature control, maintenance, cross-contamination, and employee health and hygiene. The developed reinforcement training material for retail produce stockers includes two posters, three flipcharts, one extension publication, and one training video. The proposed implementation was described considering the development or maintenance of a food safety culture. Perfluoro octanoic acid (PFOA) and perfluorooctane sulfonic acid (PFOS) used to be added to food contact paper packaging and can be harmful to human health. Quantification of PFOA and PFOS on seven popcorn bags and three snack and sandwich bags show that two popcorn bags contain PFOA above the method’s limit of quantitation and all
Promoting Critical Thinking through the Modification of Questioning Verbs in Writing Assignments: A Study / El Fomento del Pensamiento Crítico a través de la Modificación de Verbos Interrogativos en Actividades de Escritura: Un Estudio

Este estudio propone un objetivo doble. Por un lado, un análisis del pensamiento crítico y su aplicación a través de la escritura en alumnos de 3º de la E.S. O. Para ello, se modificó el lenguaje de las preguntas de escritura del libro de texto. A continuación, se implementó una unidad didáctica que destaca la importancia del pensamiento reflexivo para el desarrollo de textos más ricos. Por tanto, el objetivo del estudio es la modificación de verbos de susodichas preguntas por otros en niveles altos de la taxonomía de Bloom. Esta información se recogió a través de observación, cuestionarios inicial y final, y una unidad didáctica con actividades de escritura evaluadas. Abstract The aim of the present study is twofold. First off, an analysis regarding 3rd E.S. O students' critical thinking application was procured from their performance from a piece of writing. To promote critical thinking, modification of the language of questions in the course book was purposely executed. This was then followed by an implementation of a whole Didactic Unit designed to enhance the role of reflective questions in the creation of more complex writings. This language modification was erected through the use of verbs contained in Bloom’s taxonomy higher orders. The changes that led students to write longer texts or express more elaborate ideas are also addressed. The data was collected via observation, pre and post questionnaires, and writing assignments. Keywords: Critical thinking; Writing; Bloom’s taxonomy; Student motivation; Questions.
AMALAN PENGURUSAN KEWANGAN MAHASISWA

Makalah ini bertujuan untuk menentukan pengaruh pengetahuan kewangan dan corak perbelanjaan terhadap amalan pengurusan kewangan mahasiswa. Kajian yang berbentuk kuantitatif ini dilakukan dengan mengaplikasikan analisis korelasi dan regrasi bagi mengenalpasti hubungan dan pengaruh pengetahuan kewangan serta corak perbelanjaan terhadap permasalahan. Usaha ini dilakukan lanjutan daripada masalah pengurusan kewangan di kalangan mahasiswa yang disebabkan oleh kurangnya pengetahuan dalam mengurus perbelanjaan serta kelemahan menguruskan corak perbelanjaan. Hasil dapatan kajian menunjukkan hanya satu daripada dua pembolehubah tidak bersandar iaitu pengetahuan kewangan mempengaruhi amalan pengurusan kewangan mahasiswa. Justeru, kajian ini diharapkan dapat membantu mahasiswa dalam mengurus amalan kewangan mereka di masa hadapan. Kata Kunci : Amalan Pengurusan Kewangan, Pengetahuan, Corak Perbelanjaan.
The proton radius: are we still puzzled?

The proton radius puzzle began in 2010 when the CREMA Collaboration released their measurement of the proton radius from muonic hydrogen spectroscopy: $r_{p}=0.84184(67)$ fm, This was five standard deviations smaller that the accepted CODATA value of that time (0.8768(69) fm), and sparked an enduring and intriguing puzzle. Since that first measurement, many theories have been formed as to why the proton radius appears smaller when measured with muons than it does when measured with electrons. Many new measurements have also been made in an attempt to resolve the puzzle. We will detail the current status of the proton radius puzzle, and review future experimental plans, with a focus on the MUon proton Scattering Experiment (MUSE).
Distribution of Coronary Artery Anomalies and Their Evaluation with Different Imaging Modalities

Introduction: Coronary artery anomalies (CAA) are diverse abnormalities. Methods: A retrospective review of coronary imaging of 17,245 patients over 2 years was performed. Patients with CAA detected on echocardiography, invasive coronary angiography (CAG) and multidetector computed tomographic angiography (MDCTA) were compared. Results: CAAs were detected in 257 patients (1.49%). Prevalence were: absent left main trunk- 0.319%, anomalous coronary artery from opposite sinus (ACAOS)- 0.516%, coronary fistulae- 0.203%, myocardial bridge- 0.093%, malignant anomalies- 0.3%. The commonest CAA was absent left main trunk. The yield of echocardiography negatively correlated with age (r=-0.6). CAG and MDCTA were equal (p=1) for detection of absent left main trunk. CAG had low sensitivity (58.3%) and MDCTA was better than it (p<0.01) for detection of abnormal high origin. For ACAOS, detection by both were not different (p=0.5) but the course was delineated better with MDCTA than with CAG (p=0.05). Both were equal for detection of intramyocardial course (p=0.5). However, MDCTA delineated its course better than CAG (p<0.01). Echocardiography had 93% sensitivity for fistula in those <12 years in age. Radiation exposure with CAG, 7.3 ± 2mSv, was lower than that with MDCTA, 14.5 ± 3mSv (p<0.01). It correlated with CAA score (r=0.3), with CAG but not with MDCTA. Contrast exposure correlated with CAA score (r=0.4) for adults with CAG but not with MDCTA. Conclusion: Echocardiography reliably detects CAAs in children. CAG and MDCTA are comparable for detection of most CAA. MDCTA delineates the course better than CAG. For MDCTA, radiation exposure is not correlated with complexity of CAA in contrast to that with CAG.
CO2 narcosis influences the memory of honey bees

Carbon dioxide is a relatively inert gas produced as a by-product of cellular respiration and is often used during various experimental manipulations of bees, as well as in beekeeping practices. However, a high concentration of carbon dioxide can affect the fitness of insects and even shorten their lives. Here, we tested the impact of exposure to carbon dioxide on the memory of foraging bees by performing a field experiment to test the spatial orientation of bees in terms of their ability to return to the nest. Additionally, we performed two laboratory experiments designed to test the short- and long-term memory of workers. Carbon dioxide had a clear negative impact on both the short-term memory and, uniquely, the long-term memory of worker bees. The laboratory results were confirmed by the field study, in which the bees had difficulty finding their way back to the nest after treatment with carbon dioxide. These results indicate that the use of carbon dioxide on foraging workers in research experiments should be limited, as it can indirectly affect the results of scientific research as well as colony conditions.
Biological data questions the support of the self inhibition required for pattern generation in the half center model

Locomotion control in mammals has been hypothesized to be governed by a central pattern generator (CPG) located in the circuitry of the spinal cord. The most common model of the CPG is the half center model, where two pools of neurons generate alternating, oscillatory activity. In this model, the pools reciprocally inhibit each other ensuring alternating activity. There is experimental support for reciprocal inhibition. However another crucial part of the half center model is a self inhibitory mechanism which prevents the neurons of each individual pool from infinite firing. Self-inhibition is hence necessary to obtain alternating activity. But critical parts of the experimental bases for the proposed mechanisms for self-inhibition were obtained in vitro, in preparations of juvenile animals. The commonly used adaptation of spike firing does not appear to be present in adult animals in vivo. We therefore modeled several possible self inhibitory mechanisms for locomotor control. Based on currently published data, previously proposed hypotheses of the self inhibitory mechanism, necessary to support the CPG hypothesis, seems to be put into question by functional evaluation tests or by in vivo data. This opens for alternative explanations of how locomotion activity patterns in the adult mammal could be generated. Author summary Locomotion control in animals is hypothesized to be controlled through an intrinsic central pattern generator in the spinal cord. This was proposed over a hundred years ago and has subsequently been formed into a consistent theory, through experimentation and computer modeling. However, critical data that support the neuronal circuitry mechanisms underpinning this theory has been obtained in experiments that greatly differ from intact animals. We propose, after trying to fill in this critical part, that new ideas are required to explain locomotion of intact animals.
Hepatic Mitochondrial Remodeling is Mechanistically Linked to Insulin Resistance in Nonalcoholic Fatty Liver Disease

Insulin resistance and altered hepatic mitochondrial function are central features of type 2 diabetes (T2D) and non-alcoholic fatty liver disease (NAFLD), but the etiological role of these processes in disease progression remains unclear. We investigated the molecular links between insulin resistance, mitochondrial remodeling, and hepatic lipid accumulation in a rodent model of T2D / NAFLD. Livers from obese, insulin resistant mice displayed augmented mitochondrial content and increased TCA cycle and pyruvate dehydrogenase (PDH) activities. Insulin sensitization with pioglitazone mitigated pyruvate-driven TCA cycle activity and PDH activation via both covalent (PDK4 and PDP2) and allosteric (intracellular pyruvate availability) mechanisms. Interestingly, improvements in insulin sensitivity and mitochondrial function were entirely dissociated from changes in hepatic triglycerides, diacylglycerides or fatty acids. Instead, we show that the mitochondrial phospholipid cardiolipin undergoes pathological remodeling in livers from obese mice and that this is reversed by insulin sensitization. Our findings identify targetable mitochondrial features of T2D and NAFLD and highlight the benefit of insulin sensitization in managing the clinical burden of obesity-associated disease.
Do independent director’s characteristics influence financial reporting quality?

ABSTRACT This paper analyses whether the role played by independent directors in monitoring the financial reporting process is affected by certain personal characteristics. Specifically, we focus on the tenure and the number of directorships that independent directors hold. Our sample is composed of US listed firms for the period 2008–2012. After performing several robustness checks and sensitivity analyses, we have documented a positive association between board independence and financial reporting quality. However, this association is presented only for certain values of directors’ tenure and external directorships. This evidence suggests that the effectiveness of independent directors in their monitoring tasks is affected by these personal characteristics. In particular, our results indicate that long tenures and a high number of directorships compromise the ability to monitor. Therefore, this paper highlights the need for a more specific approach, based on the personal characteristics of independent directors, in order to study their influence on corporate decisions. Furthermore, our evidence has direct implications for companies in the selection of board members.
Adherence to functional neurorehabilitation processes and their relation to disability and quality of life in Colombian adults with spinal cord injury

Resultados. En el 80% la discapacidad global fue leve y moderada. 66% de los participantes reportaron niveles medio y alto de adherencia. El promedio de calidad de vida general fue de 68/100. Se encontró correlación significativa, por un lado, entre el componente ambiental de la discapacidad con la adherencia global y sus factores socio-económico, equipo de asistencia sanitaria, tratamiento y paciente y, por el otro, entre el dominio ambiental de la CVRS con la adherencia global y todos sus factores (p<0.001).