Miracle-dz/UniFAR-FTUs huggingface dataset:
EFFECT OF DIETARY OREGANO SUPPLEMENTATION ON PRODUCTIVE, PHYSIOLOGICAL AND IMMUNOLOGICAL PERFORMANCE OF BROILER CHICKS

A total number of 225 unsexed-one-day old Starbro broiler chicks were randomly distributed into 5 equal experimental groups with three replicates of 15 chicks each. The first group was fed the basal diet and served as control group. The second and third groups were fed the basal diet supplemented with 0.25 and 0.50g Robadiar/kg diet, respectively. The fourth and fifth groups were fed the basal diet supplemented with 0.30 and 0.60g Orego-Stim/kg diet, respectively. The effect of these feed additives on performance of broilers were evaluated. The results obtained could be summarized as follows: broiler chicks of the fifth group recorded the best values for live body weight, body weight gain and feed conversion ratio followed by fourth, third and second treatment groups compared with the control diet. Relative weight of eviscerated carcass, heart and edible organs were significantly (P≤0.05) increased by dietary oregano groups (except the second group) compared with the control group. Also, relative weights of thymus and bursa significantly (P≤0.05) increased for the fifth group compared to the control one, while, abdominal fat (%) was significantly (P≤0.05) reduced by dietary treatments. All dietary additives significantly reduced the total counts of anaerobic and E. coli bacteria, at the same time, they increased the beneficial bacteria counts (lactobacillus), moreover, birds of fifth group recorded the lowest counts of both anaerobic and E. coli bacteria, and the highest count of lactobacillus compared to other treatment groups and untreated control group. Chicks fed the fifth diet significantly (P≤0.05) had high plasma total protein, globulin and glucose concentrations compared to control diet. Each of plasma total lipids, total cholesterol and triglycerides concentration was significantly (P≤0.05) decreased in all supplemented diet groups comparing to the control group. However, plasma concentrations of aspartate amino transaminase and alanine transaminase activities as well as albumin/globulin ratio were not significantly affected. There were significant (P≤0.05) increases in the counts of erythrocytes and total counts of leukocytic, but no in lymphocytes, heterophil and heterophil/lymphocytes ratio due to tested supplements compared to the control. Economic efficiency values increased by about 7.43, 10.00, 15.14 and 16.71% for second, third, fourth and fifth groups, respectively over the control group. Supplementing diet with 0.60g Orego-Stim/kg diet significantly improved the growth performance, carcass characteristic and some physiological and immunological parameters of broiler chicks.
Measurement of Instantaneous Wave-free Ratio through a Diagnostic Catheter: Comparison of the Results between 4Fr and 5Fr

Coronary pressure measurement, using a 0.014-inch pressure wire, has been widely used for the measurement of Instantaneous Wavefree Ratio (iFR), which is a new physiological index of coronary artery severity calculated during a wave-free period and without hyperaemic stimulation, with good repeatability [1–4]. Recently, an iFR value of 0.89 was used as a threshold cut-off value in two multi-centre, randomised, clinical trials that investigated whether the iFR was non-inferior to Fractional Flow Reserve (FFR). These studies revealed that the iFR-guided revascularization strategy was non-inferior to the FFR-guided revascularization strategy, in terms of Major Adverse Cardiac Events (MACE) at 12 months [5,6]. The use of a guiding catheter has been recommended for assessing coronary pressure measurement [7]. In Japan, following coronary angiography, a 4Fr or 5Fr diagnostic catheter has been often used for pressure assessment in cases presenting with intermediate coronary stenosis; however, the variation in iFR values between the 4Fr and 5Fr diagnostic catheter has not been elucidated. The present study aimed to evaluate the differences in iFR values, safety, and the rate of successful iFR measurement between the 4Fr and 5Fr diagnostic catheters. A RT I C L E I N F O
Chondrocyte-specific RUNX2 Overexpression Causes Chondrodysplasia During Development, but is Not Sufficient to Induce OA-like Articular Cartilage Degeneration in Adult Mice Without Injury

RUNX2 is a transcription factor critical for chondrocyte maturation and normal endochondral bone formation. It promotes the expression of factors catabolic to the cartilage extracellular matrix and is shown to be upregulated in human osteoarthritic cartilage and in murine articular cartilage following joint injury. To date, in vivo studies of RUNX2 overexpression in cartilage have been limited to forced expression in osteochondroprogenitor cells preventing investigation into the effects of chondrocyte-specific RUNX2 overexpression during development or in postnatal articular cartilage. Here, we used the Rosa26Runx2 allele in combination with the inducible Col2a1CreERT2 transgene or the inducible AcanCreERT2 knock-in allele to achieve chondrocyte-specific RUNX2 overexpression (OE) during embryonic development or in the postnatal articular cartilage of adult mice, respectively. RUNX2 OE was induced at E13.5 for all developmental studies and resulted in a phenotype resembling chondrodysplasia at E18.5. Histology and in situ hybridization analyses suggest an early onset of chondrocyte hypertrophy and accelerated terminal maturation in the limbs of the RUNX2 OE embryos compared to control embryos. Additionally, RUNX2 OE resulted in enhanced TUNEL staining indicative of increased chondrocyte apoptosis throughout all regions of the growth plate. For all postnatal studies, RUNX2 OE was induced at 2 months of age. Surprisingly, no histopathological signs of OA or cartilage catabolism were observed even six months following induction of RUNX2 OE in postnatal animals. Using the meniscal/ligamentous injury (MLI), a surgical model of knee joint destabilization and meniscal injury, however, we found that chondrocyte-specific RUNX2 OE accelerates the progression of OA pathogenesis following joint trauma. Histomorphometry and OARSI scoring confirmed decreased cartilage area two months following injury in the RUNX2 OE joints compared to control joints. Further, the numbers of MMP13-positive and TUNEL-positive chondrocytes were significantly greater in the articular cartilage of the RUNX2 OE joints compared to control joints one month following injury. Collectively, our data support that RUNX2 OE in growth plate chondrocytes is sufficient to promote their hypertrophy and terminal maturation during development. While RUNX2 overexpression alone is surprisingly insufficient to induce catabolic changes to the postnatal articular cartilage, it can accelerate the progression of post-traumatic OA. These results suggest that although increased RUNX2 expression may predetermine the rate of OA onset and/or progression following traumatic joint injury, alone this change is not sufficient to initiate the OA degenerative process.
Azo- and butadiyne-linked 5,10-diarylporphyrins

Porphyrins are one of Nature’s essential building blocks that play an important role in several biological systems including oxygen transport, photosynthesis, and enzymes. Their capacity to absorb visible light, facilitate oxidation and reduction, and act as energy- and electron-transfer agents, in particular when several are held closely together, is of interest to chemists who seek to mimic Nature and to make and use these compounds in order to synthesise novel advanced materials. During this project 26 new 5,10-diarylsubstituted porphyrin monomers, 10 dimers, and 1 tetramer were synthesised. The spectroscopic and structural properties of these compounds were investigated using 1D/2D 1H NMR, UV/visible, ATR-IR and Raman spectroscopy, mass spectrometry, X-ray crystallography, electrochemistry and gel permeation chromatography. Nitration, amination, bromination and alkynylation of only one as well as both of the meso positions of the porphyrin monomers have resulted in the expansion of the synthetic possibilities for the 5,10-diarylsubstituted porphyrins. The development of these new porphyrin monomers has led to the successful synthesis of new azo- and butadiyne-linked dimers. The functionalisation of these compounds was investigated, in particular nitration, amination, and bromination. The synthesised dimers containing the azo bridge have absorption spectra that show a large split in the Soret bands and intense Q-bands that have been significantly redshifted. The butadiyne dimers also have intense, red-shifted Q-bands but smaller Soret band splittings. Crystal structures of two new azoporphyrins have been acquired and compared to the azoporphyrin previously synthesised from 5,10,15- triarylsubstituted porphyrin monomers. A completely new cyclic porphyrin oligomer (CPO) was synthesised comprising four porphyrin monomers linked by azo and butadiyne bridges. This is the first cyclic tetramer that has both the azo and butadiyne linking groups. The absorption spectrum of the tetramer exhibits a large Soret split making it more similar to the azo- dimers than the butadiyne-linked dimers. The spectroscopic characteristics of the synthesised tetramer have been compared to the characteristics of other cyclic porphyrin tetramers. The collected data indicate that the new synthesised cyclic tetramer has a more efficient ð-overlap and a better ground state electronic communication between the porphyrin rings.
HNI9 and HY5 maintain ROS homeostasis under high nitrogen provision in Arabidopsis

One sentence summary Excessive N nutrition leads to ROS accumulation, and requires the function of major transcriptional regulators to maintain plants under physiological conditions. Author contributions An.M. and A.G. conceived research plans and supervised the experiments; F.B, Am.M. , J.B. , L.L. , L.B. and An.M performed most of the experiments; F.B, Am.M. , J.B. , G.K. , L.L. , L.B. and An.M analyzed the data; An.M. wrote the article with contributions of all the authors. Competing interests The authors declare no competing financial interests. Summary Reactive Oxygen Species (ROS) can accumulate in cells at excessive levels, leading to unbalanced redox status and to a potential oxidative stress, which can have damaging effects to the molecular components of plant cells. Several environmental conditions have been described as causing an elevation of ROS production in plants. Consequently, this requires the expression of detoxification responses in order to maintain ROS homeostasis at physiological levels. In case of mis-regulation of the detoxification systems, oxidative stress can lead ultimately to growth retardation and developmental defects. Here, we demonstrate that Arabidopsis plants growing under high nitrogen environment have to express a set of genes involved in detoxification of ROS in order to maintain ROS at physiological levels. We show that the chromatin factor HNI9 is an important actor of this response, required for the expression of these detoxification genes. Mutation in HNI9 leads to elevated ROS levels, and to ROS-dependent phenotypic defects under high but not low N provision. In addition, we identify HY5 as one of the major transcription factors also required for the expression of this detoxification program under high N condition. Our results demonstrate the requirement of a balance between N nutrition and ROS production, and identified the first major regulators required to control ROS homeostasis under excessive N nutrition.
Mediated and moderated model of the willingness to pay for halal transportation

Purpose This paper aims to identify the factors of willingness to pay for halal transportation among Muslim consumers in Malaysia by extending the theory of planned behaviour with knowledge and religiosity. Design/methodology/approach Applying a purposive sampling method, data were gathered from questionnaires distributed to Muslim consumers at Malls in Kuala Lumpur and Putrajaya. From 250 Muslims who were approached, 200 respondents agreed to answer the questionnaire. SMART-PLS 3.2. 8. was used to analyse the data for this study using a structural equation modelling (SEM) approach. Findings Attitude (ATT), Subjective Norm (SN) and Perceived Behavioural Control (PBC) have a positive relationship with the Willingness to Pay (WTP). However, religiosity is found as an insignificant factor towards the WTP. Knowledge and religiosity are significant predictors of the attitude. Attitude is found to have a mediating effect on the relationship between knowledge and the WTP, and for religiosity towards the WTP. Awareness moderates the positive relationship between ATT and the WTP for halal transportation services. Meanwhile, awareness is found as an insignificant moderator between SN and the WTP, and for the PBC and the WTP. Practical implications The findings provide useful information on the WTP for halal transportation. Related parties such as the government, halal transport service providers and customers can use these findings to plan further action to enhance the WTP for halal transportation Originality/value The study reveals the capability of the TPB to identify the factors of WTP for halal transportation among Muslim consumers in Malaysia. The findings also show the moderation effects of awareness on the TPB. The findings also enrich the literature on the WTP in halal studies
Automatic Music Generator Using Recurrent Neural Network

In this paper, we developed an automatic music generator with midi as the input file. This study uses long short-term memory (LSTM) and gated recurrent units (GRUs) network to build the generator and evaluator model. First, a midi file is converted into a midi matrix in midi encoding process. Then, each midi is trained on a single layer and double stacked layer model of each network as a generator model. Next, classification model, based on LSTM and GRU, are trained and chosen as an objective evaluator to analyze the performance of each generator model which classify each midi based on its musical era. Subjective evaluation is conducted by an interview with volunteer respondents with various backgrounds such as classical music interest, performance, composer, and digital composer. The result shows that the double stacked layer GRU model perform better to resemblethecomposerpatterninmusicwith70%scoreofrecall.Moreover,subjectiveevaluationshowsthatthegeneratedmusic islistenableandinterestingwiththehighestscoreof6.85outof10ondoublestackedlayerGRU.
Classification Method of Ethnic Minority Patterns Based on Faster R-CNN

The pattern on the costumes and brocades of ethnic minorities are of profound significance, but they are various and often composed of many kinds of patterns. It is not accurate and time-consuming to classify them only by artificial methods. Taking Yao’s pattern symbols as an example, this paper collects and arranges the pattern pictures on clothing and brocade, preprocesses the pictures and labels the patterns on the processed pictures according to the preliminary classification. After the data set is made, the data set is trained and tested by Faster R-CNN algorithm. The results show that this method can effectively identify and classify the patterns of Yao nationality while reducing the time-consuming, and the average accuracy can reach 88.71%. It provides a useful exploration to help more ethnic minorities realize the intelligent classification of patterns.
The Long-run Relationships between Number of Patents and Economic Growth

Purpose: The aim of the article was to determine whether there was a long-term relationship between the level of economic growth and development of Germany and the number of granted patents and the so-called valuable patents. The empirical analysis was based on available statistical data for the period of 1872–1913. Econometric methods were used, including stationary test using ADF and KPSS tests, Johansen cointegration test. Findings: The research results showed that all analysed time series were non-stationary, and were integrated of order I(1). The Johansen’s test results excluded any long-term relationship between the growth and economic development of Germany, and the number of granted patents, including valuable patents. Practical Implications: The adoption of the patent law by the Reichstag (1877) was an important step in the protection of intellectual property of the united Germany, so it was reasonable to determine whether there was a correlation between the analysed variables. The hypotheses about long-term interdependence could not be confirmed, which may have an impact on further studies of the factors of economic growth in the Second German Reich. Originality/Value: It was particularly important to examine whether the number of granted patents (including valuable patents) had a positive effect on Germany’s long-term economic growth and development (and the other way around). The obtained results are an extension of the author’s research to date, in this respect by providing some contribution to the development of cliometrics (not very popular in Europe). The research results will allow, in the next stage, to further search for determinants of Germany’s economic growth, including determining interdependence in the short term, using the impulse response function.
Time of Maximum Action of Leaf-Methanol Extract of Pseudopanax Arboreus (Araliaceae) on the Sexual Activi-ty of Amitriptyline-Induced Sexually Impaired Male Rats

Leaves of Pseudopanax arboreus have been employed traditionally for male potency and virility for almost a century by the people of the Bayang Tribe of the Manyu Division of Cameroon without any scientific investigation. According to their folk medicine, its leaf-maceration is used to improve on male sexual performance or treat male sex-related ailments such as Erectile Dysfunction (ED), ejaculatory dysfunction, disorders of sexual desire and low sperm count by administering a total daily volume of 250 ml of maceration of 20 leaves to an adult male. In previous studies, we evaluated the effects of its leaf-aqueous extract on the sexual behaviour of normal male rats [1] and the effects of the leaf-methanolic extract on the sexual activity of amitriptyline-induced sexually impaired male rats [2]. In the present experiment, we aimed at determining the time of maximum action of the leaf-methanol extract of the plant on the sexual activity of amitriptyline-induced sexually impaired male rats using the number of ejaculatory series produced within every 30 minutes of observation.
PENGARUH SELF-EFFICACY, PERCEIVED ORGANIZATIONAL SUPPORT DAN EMPLOYEE ENGAGEMENT TERHADAP ORGANIZATIONAL CITIZENSHIP BEHAVIOR PADA PERUSAHAAN DAERAH AIR MINUM KOTA PADANG

Penelitian ini bertujuan untuk mengetahui seberapa besar Pengaruh Self-efficacy, Perceived Organizational Support, dan Employee Engagement terhadap Organizational Citizenship behavior pada PDAM Kota Padang. Variabel penelitian yaitu Self-efficacy (X1), Perceived Organizational Support (X2) Employee Engagement (X3) dan Organizational Citizenship Behavior (Y). Metode pengumpulan data melalui survei dan menyebarkan kuesioner kepada karyawan sebagai responden. Metode analisis yang digunakan adalah uji validitas dan reliabilitas, analisis korelasi, analisis regresi berganda, untuk uji hipotesis digunakan yaitu uji t dan uji F serta dilakukan uji outer model. Hasil penelitian menunjukan (a) Self-efficacy berpengaruh positif dan signifikan terhadap OCB sebesar 3,117 dengan tingkat signifikan (0,003 0,05) (c) Employee Engagement berpengaruh positif dan tidak signifikan terhadap OCB sebesar 1,089 dengan tingkat signifikan (0,280<0,05). Sumbangan variabel Self-efficacy, Perceived Organizational Support, dan Employee Engagement terhadap OCB sebesar 0,550 atau 55%, sedangkan selebihnya di pengaruhi variabel lain diluar model penelitian ini. Indicator atau item pernyataan yang paling dominan pada variabel Self-efficacy dengan nilai sebesar 0,735 adalah “kesulitan tugas mampu dihadapi”, pada variabel Perceived Organizational Support dengan nilai 0,802 adalah “job security”, dan pada variabel Employee Engagement dengan nilai 0,849 adalah “ketangguhan mental yang dimiliki”, sedangkan pada variabel Organizational Citizenship Behavior dengan nilai sebesar 0,750 adalah “tepat waktu”.
Quantifying Coastal Fluvial Morphodynamics Over the Last 100 Years on the Lower Rio Grande, USA and Mexico

Downstream changes in fluvial channel morphology are commonly observed in association with the backwater zone, where rivers transition from quasi‐uniform flow with normal‐flow depth to gradually varying flow. This transition is linked to changes in channel morphology and mobility and resulting fluvial stratigraphy. However, the majority of systems studied to date are perennial rivers with relatively consistent flow conditions. Here we investigate the evolution of a large river with significant flood‐to‐baseflow variability as it transverses and builds a large delta. We provide the first comprehensive study of the morphology and morphodynamics of the lower Rio Grande, a major continental drainage system that enters the western Gulf of Mexico. We quantify the morphology of the current Rio Grande channel and document spatial trends in channel geometry and kinematics using lidar, historical surveys, and hydrographic analysis. The modern Rio Grande channel morphology does not significantly vary toward the coast. Rather, the channel width, levee, and bed slopes remain nearly constant for ~200 river km. We find historical migration rates between 10 and 100 m/yr with no significant reduction toward the coast in contrast to previously studied systems. We propose that this invariant channel geometry and sustained high migration rates are signatures of the channel not requiring adjustment within the lower coastal reach to accommodate baseflow conditions, and the channel remains continuously adjusted solely to peak flow conditions.
Plasma-assisted directed vapor deposition for synthesizing lithium phosphorus oxynitride thin films

This dissertation explores a new vapor deposition route for synthesizing lithium phosphorus oxynitride (Lipon) thin-film electrolytes for rechargeable thin-film Li/Li-ion batteries. These batteries operate at a high voltage (around 4.0 V) and exhibit a long cyclic life (over 10,000 charge/discharge cycles). These features stem from the extremely low leakage current of the Lipon film electrolyte when in contact with a lithium anode, and its good Li-ion conductivity (in the 10 -6 -10 -7 S/cm range). Lipon films have usually been synthesized by reactive RF-magnetron sputtering, which suffers from a very low deposition rate (~2 nm/min). It therefore takes many hours to make the 1-2 μm thick films needed for battery applications. Other deposition approaches, such as Pulsed Laser Deposition, Ion Beam Assisted Deposition, and E-beam evaporation, have been investigated but resulted in unsatisfactory Lipon film performance. Here, a plasma-assisted directed vapor deposition (PA-DVD) approach has been explored to synthesize dense, amorphous Lipon films. Unlike conventional e-beam evaporation, the e-beam based DVD approach employs an annular nozzle to generate a rarefied supersonic inert gas jet around the periphery of an electron beam evaporated source material. The vapor is entrained in the jet and rapidly transferred to a substrate. Because the supersonic gas jet focuses the vapor (it impedes lateral spreading of the vapor flux), most of the evaporant reaches the substrate. As a result, the deposition rate of Lipon films can be potentially much higher than most other processes. The PA-DVD approach used here employs a hollow cathode to create low-energy plasma through