Miracle-dz/UniFAR-FTUs huggingface dataset:
Identifiability of Finite Mixtures for Directional Data

For an example with both (1.1) and (1.2) applied to bimodal circular data, see Mardia and Spurr (1973). Two questions of identifiability arise here. (i) Are finite mixtures of von Mises densities identifiable? (ii) Are densities of the form (1.1) always distinct from densities of the form (1.2)? One purpose of this paper is to show in a wide variety of situations that the answer to both these questions is "yes". More generally, the theorem proved below shows the identifiability of finite mixtures for a class of distributions which is wide enough to include both of the above choices. The identifiability of von Mises mixtures was first proved in Fraser, Hsu and Walker (1981), who give several references to applications of von Mises mixtures. This paper extends their results to more general distributions and more general manifolds. The classes of probability distributions covered by this paper include the following examples: the multivariate normal distribution on RP; the von Mises-Fisher, the Bingham and more general distributions on the unit sphere (Beran, 1979); a joint normal-von Mises distribution on the cylinder (Mardia and Sutton, 1978, and Johnson and Wehrly, 1978); a bivariate von Mises distribution on the torus (Mardia, 1975, and Jupp and Mardia, 1980); and more generally, a joint Bingham-von Mises-Fisher matrix distribution on the product of two Stiefel manifolds (author's reply in Mardia, 1975). The identifiability of finite mixtures of multivariate normals has been shown by Yakowitz and Spragins (1968) but the other examples seem to be new. For a general survey of finite mixtures of distributions, see for example Everitt and Hand (1981) and Behboodian (1975). The key argument in the proof of identifiability in this paper is contained in Section 3, where we show that a suitable limit in the complex plane of the ratio of two densities on the circle equals zero. The argument is similar in style to but more general than that used by Teicher (1963), Theorem 2).
Do bilinguals have an advantage in prospective memory?

ABSTRACT It is well established that bilinguals outperform monolinguals on executive function tasks. However, the effects of bilingualism on prospective memory (PM), which also requires executive functions, have not been investigated vastly. This study aimed to compare bi and monolingual participants’ PM performance in focal and non-focal PM tasks. Forty-eight Turkish-English bilinguals and forty-eight Turkish monolinguals, between the ages of 18–30, were instructed to remember responding to rarely appearing PM cues while engaged in an ongoing task. In the focal PM task, the ongoing task facilitated the processing of the PM cue, whereas the non-focal PM task impeded. The results showed no direct evidence for a bilingual advantage in PM. Moreover, the results showed a reversed effect of PM cue's focality on the ongoing task performance. These findings raise skepticism about the literature's prevalent findings and theoretical explanations. Alternative interpretations are discussed within bilingual advantage and PM theories research areas.
Oxytocin-Receptor Gene Modulates Reward-Network Connection and Relationship with Empathy Performance

Introduction Empathy traits are highly heritable and linked with reward processing. It is implicated that common variations of the oxytocin-receptor gene (OXTR) play a modulatory effect on empathic performance. However, it is unclear about the neural substrates underlying the modulatory effect of the OXTR genotype on empathic performance. This study aimed to characterize the modulatory effect of common OXTR variations on reward-circuitry function and its relationship with empathy. Methods Based on the seed of the nucleus accumbens (NAcc; a key hub of reward circuitry), we examined differences in spontaneous local activity and functional connectivity between OXTR rs2268493 genotype groups and their relationship with empathic performance among 402 high-homogeneity participants. Results Comparing with C carriers (CC/CT) group, the individuals with the rs2268493 TT genotype exhibited lower functional connectivity of the right NAcc with the medial prefrontal cortex (mPFC) and inferior frontal gyrus. Similarly lower functional connectivity was found between the left NAcc and mPFC. Consequently, no significant difference was found in the spontaneous local activity of NAcc. Discussion Our findings suggested that common OXTR variations have a modulatory effect on the connection of the NAcc with the hub of empathic networks (mPFC and IFG), which may provide insight on the neural substrate underlying the modulatory effect of OXTR on empathic behavior.
Weighted differentiation composition operators from H ∞ to Zygmund spaces

Let ϕ be an analytic self-map of the unit disk 𝔻, H(𝔻) the space of analytic functions on 𝔻 and u∈H(𝔻). The boundedness and compactness of the weighted differentiation composition operator , where n∈ℕ0, from H ∞ to Zygmund space are investigated in this paper.
On form-preserving point transformations of partial differential equations

New identities are presented relating arbitrary order partial derivatives of and for the general point transformation , . These identities are used to study the nature of those point transformations which preserve the general form of a wide class of 1 + 1 partial differential equations. These results facilitate the search for point symmetries, both discrete and continuous (Lie), and assist the search for point transformations which reduce equations to canonical, but similar, form. A simple test for the existence of hodograph-type transformations between equations of similar form is given.
LUMINOSITY CLASSIFICATION WITH THE WASHINGTON SYSTEM.

The DDO 51 filter has been added to the Washington photometric system. The strong surface gravity sensitivity of the Mg I "b" triplet and MgH bands which it monitors allows the system to easily discriminate between dwarfs and giants of late G and K spectral type. The system is especially suited as a membership criterion for abundance studies of distant cluster giants. The Mg index is insensitive to surface gravity variations among G giants. The metallicity sensitivity among giants is also relatively weak. Population I and II giants can be distinguished but no further differentiation is evident.
Immigrating and vicinity are not risk factors in the prevalence and transmission rate of human T-lymphotropic virus type 1: A Survey in an endemic region of Iran and Afghan refugees

Human T-lymphotropic virus type 1 (HTLV-1) is a retrovirus associated with two life-threatening diseases; HAM/TSP and ATLL. Due to the slow-growing HTLV-1 infection worldwide, WHO urged for elimination. A large border with Afghanistan, northeast Iran is an endemic region for HTLV-1 infection. Historically, Afghanistan has common sociocultural similarities to Persian peoples. This study was conducted to evaluate HTLV-1 prevalence in Afghan refugees. Also, the HTLV-1 transmission rate and understanding of whether or not the Silk Road has been the route of HTLV-1 infection to Iran were investigated. This case-control study was conducted in a rural area of Fariman city, with Afghan residents who migrated around 165 years ago, from 1857, the Treaty of Paris at the end of the Anglo-Persian war, and a refugee camp in Torbat-e-Jam city. These populations in HTLV-1 endemic area were compared to a segregated population of Afghan refugees in Semnan, the centre of Iran. Blood samples of 983 volunteers were assessed with the ELISA method for the presence of HTLV-1 antibodies and then confirmed by PCR technique. All samples from Afghan refugee camps, Semnan and Torbat-e-Jam, were negative for HTLV-1 infection. However, the prevalence of HTLV-1 infection in Fariman, a rural population of Afghan origin, was approximately 2.73%. The results showed that HTLV-1 is not endemic in Afghanistan, a war-stricken region with refugees distributed worldwide. The land Silk Road has not been the route of HTLV-1 transmission to Northeastern Iran. Importantly, HTLV-1 endemicity might occur during a long time of living in an endemic area.
Disposition Effect: Brazilian Investors' Behavior during the Covid-19 Pandemic

This study investigates the disposition effect with regard to Brazilian investors, with focus on the year 2020. The database is composed by more than 12,000 trades by 274 investors. We follow the method of Odean (1998) to estimate the proportions of gains and losses realized and test the null hypothesis of equality of these proportions in each portfolio. The results suggest that Brazilian investors behave in line with the disposition effect. They sell winning stocks too early and hold losing stocks too long. A stock that is gaining value is more likely to be sold from day to day compared to a stock that is losing value. The disposition effect was not found in March, which suggests that investors employed a loss-limit during periods of market stress, no matter if the stock went up or down.
Synthesis of CO and CO2 Molecules by UV Irradiation of Water Ice-covered Hydrogenated Carbon Grains

We present the results of UV irradiation with Lyα photons of carbon grains with a water ice cap at 11 K. Formation of CO and CO2 molecules takes place during irradiation. An estimation of the formation cross section of these molecules by Lyα photons has been obtained from the intensity increase of their infrared stretching bands as a function of the photon fluence. The fraction of carbon in the grains converted to CO and CO2 by UV photons is 0.06 and 0.05, respectively. The spectral profile of the CO stretching feature and that of the CO2 bending mode indicate a polar environment for these molecules. On the basis of the present laboratory results and those obtained in previous work on ion irradiation of similar samples, it has been possible to estimate the contribution of polar CO and CO2 produced on carbon grains by energetic processing to the observed column densities of these molecules for dense clouds whose visual extinction is known. A significant amount of polar CO and CO2 is produced through the mechanism we have studied. Furthermore, we have found that the laboratory profile of the bending band of CO2 produced on carbon grains is compatible with that observed toward the field star Elias 16.
Identification of Novel Pathways Regulated by APE1/Ref-1 in Human Retinal Endothelial Cells

APE1/Ref-1 (apurinic/apyrimidinic endonuclease 1, APE1 or APEX1; redox factor-1, Ref-1) is a dual-functional enzyme with crucial roles in DNA repair, reduction/oxidation (redox) signaling, and RNA processing and metabolism. The redox function of Ref-1 regulates several transcription factors, such as NF-κB, STAT3, HIF-1α, and others, which have been implicated in multiple human diseases, including ocular angiogenesis, inflammation, and multiple cancers. To better understand how APE1 influences these disease processes, we investigated the effects of APEX1 knockdown (KD) on gene expression in human retinal endothelial cells. This abolishes both DNA repair and redox signaling functions, as well as RNA interactions. Using RNA-seq analysis, we identified the crucial signaling pathways affected following APEX1 KD, with subsequent validation by qRT-PCR. Gene expression data revealed that multiple genes involved in DNA base excision repair, other DNA repair pathways, purine or pyrimidine metabolism signaling, and histidine/one carbon metabolism pathways were downregulated by APEX1 KD. This is in contrast with the alteration of pathways by APEX1 KD in human cancer lines, such as pancreatic ductal adenocarcinoma, lung, HeLa, and malignant peripheral nerve sheath tumors. These results highlight the unique role of APE1/Ref-1 and the clinical therapeutic potential of targeting APE1 and pathways regulated by APE1 in the eye. These findings provide novel avenues for ocular neovascularization treatment.
Microfluidics Underground: A Micro-Core Method for Pore Scale Analysis of Supercritical CO2 Reactive Transport in Saline Aquifers

Carbon sequestration in microporous geological formations is an emerging strategy for mitigating CO2 emissions from fossil fuel consumption. Injection of CO2 in carbonate reservoirs can change the porosity and permeability of the reservoir regions, along the CO2 plume migration path, due to CO2-brine-rock interactions. Carbon sequestration is effectively a microfluidic process over large scales, and can readily benefit from microfluidic tools and analysis methods. In this study, a micro-core method was developed to investigate the effect of CO2 saturated brine and supercritical CO2 injection, under reservoir temperature and pressure conditions of 8.4 MPa and 40 °C, on the microstructure of limestone core samples. Specifically, carbonate dissolution results in pore structure, porosity, and permeability changes. These changes were measured by X-ray microtomography (micro-CT), liquid permeability measurements, and chemical analysis. Chemical composition of the produced liquid analyzed by inductively coupled plasma-atomic emission spectrometer (ICP-AES) shows concentrations of magnesium and calcium in the produced liquid. Chemical analysis results are consistent with the micro-CT imaging and permeability measurements which all show high dissolution for CO2 saturated brine injection and very minor dissolution under supercritical CO2 injection. This work leverages established advantages of microfluidics in the new context of core-sample analysis, providing a simple core sealing method, small sample size, small volumes of injection fluids, fast characterization times, and pore scale resolution.
Explosive ignition by the collapse of cavities

Cavities are present in a wide range of energetic systems by design or mischance. In either case, the presence of a bubble sensitizes the explosive to ignition when it is collapsed by a shock pulse. In this case, the temperature within the cavity is high as well as the collapse being asymmetric. Many authors attribute ignition to the adiabatic heating of the trapped gas. In this work, cavities are created within an ammonium nitrate emulsion matrix. They are large enough to be visualized using conventional optics with a high-speed camera. These relatively large cavities collapse in such a way that the ignition event is controlled by the hydrodynamic pressures generated by the impact of a high–speed liquid jet. It is thought that other mechanisms may dominate at different length–scales.
Full posterior analysis of three parameter lognormal distribution using gibbs sampler

The paper provides full posterior analysis of three parameter lognormal distribution using Gibbs Sampler, an important and useful Markov chain Monte Carlo technique in Bayesian computation. The extension of the algorithm is given to cover the case of censored data. It has been found that the censoring which creates special problem in the analysis of lognormal model with non-closed form cdf, can be routinely tackled by the use of Gibbs sampler. Suitable numerical illustrations are provided for both complete and censored situations.
Potential of Epipremnum aureum and Bacopa monnieri (L.) Wettst for Saline Phytoremediation in Artificial Wetlands

The aim of this research was to evaluate the phytoremediative potential of Epipremnum aureum and Bacopa monnieri to improve the chemical properties of irrigation water exposed to the following two saline concentrations: highly saline (EC 2000 μS cm−1) and severely saline (EC 4000 μS cm−1). The artificial wetlands used in this experiment were of the free water surface type, considering a hydraulic retention time of 42 days. The evaluated treatments were configured as follows: T1 (B. monnieri [control, 300 μS cm−1]), T2 (B. monnieri [2000 μS cm−1]), T3 (B. monnieri [4000 μS cm−1]), T4 (E. aureum [control, 300 μS cm−1]), T5 (E. aureum [2000 μS cm−1]), T6 (E. aureum [4000 μS cm−1]), T7 (B. monnieri + E. aureum [control, 300 μS cm−1]), T8 (B. monnieri + E. aureum [2000 μS cm−1]), and T9 (B. monnieri + E. aureum [4000 μS cm−1]). The results showed that the species B. monnieri and E. aureum (both separately and together) showed a good ability to reduce the salinity of the irrigation water. However, B. monnieri showed a greater ability of phytoremediation, to the point of improving its chemical properties and reducing potential damage to the soil to use this water. In the highly saline group, B. monnieri accumulated 7.992 g per experimental unit and achieved to reduce of the pH from 7.96 to 7.75, EC from 2000 μS cm−1 to 670 μS cm−1, SAR from 13.54 to 3.91 and ESP from 20.17 to 5.83, which allowed it to go from (C3-S3) to (C3-S1). In the severely saline group, B. monnieri accumulated 13.494 g per experimental unit and achieved to reduce the pH from 8.14 to 7.91, EC from 4000 μS cm−1 to 1730 μS cm−1, SAR from 27.35 to 8.73, ESP from 40.35 to 13.01, which allowed it to go from (C4-S4) to (C3-S2).
Turbulent patches in a stratified shear flow

Turbulence measurements within an artificially generated turbulent patch embedded in a stratified shear flow are presented. The results indicate that the enhanced patch growth that has been observed at background gradient Richardson numbers on the order unity can be attributed to the onset of shear-induced mixing at the patch boundaries rather than enhanced interaction between turbulence and shear that causes increased turbulence levels within the patch.
The Impact of Digital Organizational Culture and Digital Capability on Organizational Performance through Digital Innovation Mediation in the COVID-19 Era: A Study on Indonesian Pharmaceutical SOEs

The COVID-19 pandemic has negatively impacted the performance of pharmaceutical companies and must be addressed appropriately. This study aims to determine how digital organizational culture, digital capability, and digital innovation impact organizational performance. The partial least squares structural equation modeling (PLS-SEM) was utilized to analyze the data obtained from 238 respondents affiliated with Indonesian pharmaceutical state-owned enterprises (SOEs). The results of this study suggest that while digital organizational culture does not directly affect organizational performance, it does so indirectly through digital innovation, which acts as a mediating variable. Second, digital capability affects organizational performance directly as well as indirectly through digital innovation. This study empirically provides confirmation of how organizational performance is achieved in pharmaceutical companies, especially during the COVID-19 era. In addition, the findings show some substantial implications for management by focusing on digital organizational culture and digital capability as fundamental predictors of organizational performance through digital innovation.Alternate :Pandemik COVID-19 telah menjejaskan prestasi syarikat farmaseutikal secara negatif dan mesti ditangani dengan sewajarnya. Kajian ini bertujuan untuk menentukan bagaimana budaya organisasi digital, keupayaan digital, dan inovasi digital mempengaruhi prestasi organisasi. Pemodelan persamaan struktur kuasa dua terkecil separa (PLS-SEM) digunakan untuk menganalisis data yang diperoleh daripada 238 responden yang bergabung dengan syarikat berkaitan kerajaan (GLC) farmaseutikal Indonesia. Hasil kajian ini menunjukkan bahawa walaupun budaya organisasi digital tidak secara langsung mempengaruhi prestasi organisasi, ia melakukannya secara tidak langsung melalui inovasi digital, yang bertindak sebagai pembolehubah pengantara. Kedua, keupayaan digital mempengaruhi prestasi organisasi secara langsung dan juga tidak langsung melalui inovasi digital. Kajian ini secara empirikai memberikan pengesahan tentang bagaimana prestasi organisasi dicapai dalam syarikat farmaseutikal, terutamanya semasa era COVID-19. Di samping itu, penemuan menunjukkan beberapa implikasi yang besar untuk pengurusan dengan memberi tumpuan kepada budaya organisasi digital dan keupayaan digital sebagai peramai asas prestasi organisasi melalui inovasi digital.
Serum Catestatin Level as a Stratification Assessment Tool in Non-Critical COVID-19 Patients

Introduction: Catestatin (CST) is a peptide with immunomodulatory, anti-inflammatory, and anti-microbial activities. There are only a few studies that have investigated plasma CST levels in COVID-19 patients (mostly in ICU patients). In our work, the aim was to demonstrate serum CST levels and their correlation with clinical outcomes in a group of severe COVID-19 patients admitted to the non-ICU department. Methods: The subjects were 32 patients (25 females, 7 males) admitted to the non-ICU unit for COVID-19 patients. Results: CST levels in our cohort were higher (8.91 ± 7.00) than previously reported CST levels in control subjects. We found a significant positive correlation between serum CST levels and C-reactive protein (r = 0.423, p = 0.008), D-dimers (r = 0.395, p = 0.013), hsTNT (high-sensitivity troponin T) (r = 0.603, p < 0.001), proBNP (N-terminal pro-brain natriuretic peptide) (r = 0.569, p < 0.001), and hospitalization days (r = 0.388, p = 0.014). There was a difference between groups of participants with SOFA <3 (n = 18) and SOFA >=3 (n = 14) in catestatin serum levels (7.25 ± 3.66 vs. 11.05 ± 9.52 ng/mL), but the difference was statistically insignificant (p = 0.065). Conclusion: We considered plasma CST level at hospital admission as a possible tool for early risk assessment in non-critical COVID-19 patients. This study is an attempt to clarify the complex pathophysiological mechanisms present in the development of severe forms of SARS-CoV2 infection.
Green synthesis, Characterization and Antimicrobial potential of Selenium Nanoparticles from Ocimum gratissimum

Ocimum gratissimum L. is a perennial herbaceous plant used in the treatment of fungal and bacterial infections. Green synthesis has provided cost effective, environment friendly procedure and raising safe strategies for the synthesis of nanoparticles. This study was aimed at investigating the potential of O. gratissimum for the synthesis of selenium nanoparticles (SeNPs) and their antimicrobial activities. Phytochemical screening on aqueous extract was carried out using standard procedures. Selenium nanoparticles was biosynthesized by O. gratissimum and characterized using Visual detection, UV-Visible spectroscopy, Scanning Electron Microscope, Transmission Electron Microscope, Energy dispersive X-ray, Fourier Transform Infra-red spectroscopy and X-ray diffraction spectroscopy. Antimicrobial activity of the biosynthesized selenium nanoparticles by O. gratissimum was done using agar well diffusion method. Saponins, tannins, cardiac glycosides, terpenoids and phenols were present. The biosynthesized SeNPs had a strong plasmon resonance band at 300 nm, changes in colour from dark brown to ruby red. The SeNPs were spherical and aggregated with varying shapes and size ranged from 20 – 50 nm. Strong signal of selenium element was observed. Hydroxyl, esters, aldehyde, alkane and amine are present and responsible for the efficient stabilization and bioreduction of Selenium nanoparticle. Furthermore, biosynthesized SeNPs by O. gratissimum (OGSeNPs) exhibited higher antimicrobial activity against both Gram ositive and Gram negative bacteria. Green synthesis of nanoparticles is a promising method in the biomedical field, due to its high bioactive components.
Destruction of the Cauchy horizon in the Reissner-Nordstrom black hole

The Cauchy horizon instability in the Reissner-Nordstrom solution is investigated numerically using (2+2) formalism. The formalism is based on the metric decomposition along two null coordinates parallel to the black hole horizons. The authors show that a spacelike singularity forms to prevent an observer's reaching the Cauchy horizon and the properties of the singularity are discussed in detail. They found that if the mass of the perturbation is of an order of or greater than the mass of the initial Reissner-Nordstrom black hole, the position of the singularity tends to those in the Schwarzschild solution. They also present a highly reliable numerical scheme based on the (2+2) formalism and discuss the properties of the initial value equations which in (2+2) formalism are reduced to linear equations.