Miracle-dz/UniFAR-FTUs huggingface dataset:
Psychometric Properties of the Patient Health Questionnaire-9 in Elderly Chilean Primary Care Users

Background: This study aimed to assess the measurement properties (reliability, factor structure, and criterion validity) of the Patient Health Questionnaire (PHQ-9) as an instrument for screening major depressive disorder (MDD) in elderly primary care users in Chile. Method: About 582 participants aged between 65 and 80 years were enrolled from primary care centers. They completed the Composite International Diagnostic Interview (CIDI), a survey with sociodemographic characteristics and the PHQ-9. Results: The PHQ-9 revealed an acceptable internal consistency (ω = 0.79 [95% CI: 0.75–0.80] and α = 0.78 [95% CI: 0.75–0.81]); confirmatory factor analysis demonstrated a good fit for both 1- and 2-factor solutions. The chi-square difference test (χ2 = 0.61, gl = 1, p = 0.43) and correlation between the somatic and the cognitive-effective latent factors were very high (r = 0.97, p < 0.001), indicating that the 1 factor model was more parsimonious. Utilizing the CIDI as the gold standard, the area under the curve (AUC) was 0.88 (SE = 0.04, 95% CI: 0.84–0.90). The optimal cut-off score of ≥ 6 yielded good sensitivity and specificity for detecting MDD (0.95 and 0.76, respectively). However, considering the clinical utility index, the cut-off score of ≥9 proved to be a more effective marker for discarding cases of MDD. Conclusion: The PHQ-9 has adequate psychometric properties for elderly primary care users. In clinical settings, it showed its greatest utility in ruling out the presence of an MDD, however, its clinical value for identifying possible cases of MDD is limited. In cases above the cut-off point, it is recommended to perform a more thorough evaluation.
Lung Epithelial TRPA1 Mediates Lipopolysaccharide-Induced Lung Inflammation in Bronchial Epithelial Cells and Mice

Toll-like receptor (TLR) 4 was originally thought to be the sole pattern recognition receptor for lipopolysaccharide (LPS). Transient receptor potential ankyrin 1 (TRPA1), a Ca2+-permeant channel, has been suggested as a non-TLR receptor membrane-bound sensor of LPS. We recently reported that TRPA1 is expressed in lung epithelial cells (LECs) and mediates lung inflammation induced by cigarette smoke. However, the role of TRPA1 in LPS-induced lung inflammation has not been conclusively defined, and its underlying cellular mechanisms remain unclear. In this study, our in vitro results showed that LPS sequentially produced a cascade of events, including the elevation of intracellular Ca2+, the activation of NADPH oxidase, increase in intracellular reactive oxygen species (ROS), the activation of mitogen-activated protein kinase (MAPK)/nuclear factor-kB (NF-κB) signaling, and the induction of IL-8. The increase in intracellular Ca2+ was inhibited by HC030031 (a TRPA1 antagonist) but was unaffected by TAK-242 (a TLR-4 inhibitor). The activation of NADPH oxidase was prevented by its inhibitor apocynin, EGTA (an extracellular Ca2+ chelator), and HC030031. The increase in intracellular ROS was attenuated by apocynin, N-acetyl-cysteine (NAC, a ROS scavenger), EGTA, and HC030031. The activation of the MAPK/NF-κB signaling was halted by NAC, EGTA, and HC030031. IL-8 induction was suppressed by HC030031 and TRPA1 siRNA, and further reduced by the combination of HC030031 and TAK-242. Our in vivo studies showed that trpa1–/– mice exhibited a reduced level of LPS-induced lung inflammation compared with wild-type mice as evidenced by the alleviations of increases in vascular permeability, inflammatory cell infiltration, inflammatory cytokine levels, oxidative stress, and MAPK signaling activation. Thus, in LECs, LPS may activate TRPA1 resulting in an increase in Ca2+ influx. The increased intracellular Ca2+ leads to NADPH oxidase activation, which causes an increase in intracellular ROS. The intracellular ROS activates the MAPK/NF-κB signaling resulting in IL-8 induction. This mechanism may possibly be at work to induce lung inflammation in mice.
Comparison of Psychological Status and Investment Style Between Bitcoin Investors and Share Investors

Bitcoin has unique characteristics that have inspired people to invest in it as well as distinct drawbacks. With a rapid increase in Bitcoin prices in the short term, more investors enthusiastically began investing in it, raising concerns about a speculative bubble. This study investigated the multiple factors involved in the Bitcoin craze despite concerns about its shortcomings. In what concerns to personality traits and psychological states, online use patterns, and investment patterns, we first hypothesized that Bitcoin investors would show differences in multiple factors when compared to share investors. Based on our assumptions about these differences, we secondly hypothesized that investors’ personality, psychological states, and investment patterns could predict whether they would invest in Bitcoin or shares. In total, 307 respondents completed the research protocol and were sorted into Bitcoin investors (n = 101), share investors (n = 102), and non-investors (n = 104). A self-report questionnaire on demographic data, online use patterns, investment patterns as well as the Fear of Missing Out (FoMO) scale, Temperament and Character Inventory-Revised-Short (TCI-RS), Mood Disorder Questionnaire (MDQ), trait anxiety part of the State-Trait Anxiety Inventory (STAI-T), and the Korean version of the Canadian Problem Gambling Index (K-CPGI) were administered. The results of this study indicated that Bitcoin investments can be attributed to the interaction of multiple factors, among which personality, psychological states, and investment patterns are particularly important. Specifically, the investment pattern is the strongest predictive factor for Bitcoin investment. Bitcoin investors were distinct with regard to higher novelty seeking, higher gambling tendencies, and unique investment patterns. Thus, personality, psychological states, and investment patterns could explain the substantial investments in Bitcoin.
An adaptive self‐scheduling loop scheduler

Many shared‐memory parallel irregular applications, such as sparse linear algebra and graph algorithms, depend on efficient loop scheduling (LS) in a fork‐join manner despite that the work per loop iteration can greatly vary depending on the application and the input. Because of the importance of LS, many different methods (e.g., workload‐aware self‐scheduling) and parameters (e.g., chunk size) have been explored to achieve reasonable performance, and many of these methods require expert prior knowledge about the application and input before runtime. This work proposes a new LS method that requires little to no expert knowledge to achieve speedups close to those of tuned LS methods by self‐managing chunk size based on a heuristic of throughput and using work‐stealing to recover from workload imbalances. This method, named iCh, is implemented into libgomp for testing. It is evaluated against OpenMP's guided, dynamic, and taskloop methods and is evaluated against BinLPT and generic work‐stealing on an array of applications that includes: a synthetic benchmark, breadth‐first search, K‐Means, the molecular dynamics code LavaMD, and sparse matrix‐vector multiplication. On a 28 thread Intel system, iCh is the only method to always be one of the top three LS methods. On average across all applications, iCh is within 5.4% of the best method and is even able to outperform other LS methods for breadth‐first search and K‐Means.
Finite-Time Asynchronous Stabilization for Nonlinear Hidden Markov Jump Systems with Parameter Varying in Continuous-Time Case

The finite-time asynchronous stabilization problem has received great attention because of the wide application of actual engineering. In this paper, we consider the problem of finite-time asynchronous stabilization for nonlinear hidden Markov jump systems (HMJSs) with linear parameter varying. Compared with the existing research results on Markov jump systems, this paper considers the HMJSs which contain both the hidden state and the observed state in continuous-time case. Moreover, we consider the parameters of the systems are time varying. The aim of the paper is to design a proper observation-mode-based asynchronous controller such that the closed-loop HMJSs with linear parameter varying be stochastically finite-time bounded with H ∞ performance (SFTB- H ∞ ). Then, we give some sufficient conditions to solve the SFTB- H ∞ asynchronous controller by considering the stochastic Lyapunov–Krasovskii functional (SLKF) methods. Finally, a numerical example is used to show the validity of the main results.
The Introduction of Ethics into Cybersecurity Curricula

The article is devoted to the analysis of the problem of teaching professional ethics to future cybersecurity specialists. It is stated that professional tasks of cybersecurity specialists nowadays cannot always be solved using the identified procedures and guidelines. The dilemmas that arise are not always supported by the corresponding laws, rules or codified standards due to the much faster development of the technological basis compared to the legislative support of the professional activity. Thus, the cybersecurity specialists can face unpredictable problems that can require ethical awareness. The article analyses three international educational efforts in creating educational standards for the cybersecurity course: the National Initiative for Cybersecurity Education (NICE), the Cyber Education Project (CEP), Cybersecurity Curricula 2017 and the role of ethics in each. As well as that, the article looks at the national educational standard for this course and the international experience of embedding ethics into cybersecurity curricula, suggesting that the introduction of the ethical component into the national educational programmes would benefit the educational process.
Transitions between cigarette, ENDS and dual use in adults in the PATH study (waves 1–4): multistate transition modelling accounting for complex survey design

Introduction Even prior to 2018, electronic nicotine delivery systems (ENDS) began to dramatically change the landscape of tobacco products and product use patterns in the USA. Methods Using a Markov multistate transition model accounting for complex survey design, transition rates between never, non-current, cigarette, ENDS and dual use states were estimated for 23 253 adult participants in waves 1–4 (approximately 2013–2017) of the Population Assessment of Tobacco and Health study. We made short-term transition projections and estimated HRs for age, sex, race/ethnicity, education and income. Results Cigarette use was persistent among adults, with 89.7% (95% CI 89.1% to 90.3%) of exclusive cigarette users and 86.1% (95% CI 84.4% to 87.9%) of dual users remaining cigarette users (either exclusive or dual) after one wave. In contrast, ENDS use was less persistent, with 72.1% (95% CI 69.6% to 74.6%) of exclusive ENDS users and 50.5% (95% CI 47.8% to 53.3%) of dual users remaining ENDS users (with or without cigarettes) after one wave. Exclusive ENDS users were more likely to start cigarette use after one wave than either never users (HR 25.2; 95% CI 20.9 to 30.5) or non-current users (HR 5.0; 95% CI 4.3 to 5.8). Dual users of ENDS and cigarettes were more likely to stop using cigarettes than exclusive cigarette users (HR 1.9; 95% CI 1.6 to 2.3). Transition rates varied among sociodemographic groups. Conclusions Multistate transition models are an effective tool for uncovering and characterising longitudinal patterns and determinants of tobacco use from complex survey data. ENDS use among US adults was less persistent than cigarette use prior to 2018.
Further investigations on the avoidance of boron-oxygen related degradation by means of regeneration

Boron and oxygen contamination in Czochralski (Cz) grown silicon leads in the short term to a degradation of the charge carrier lifetime due to the formation of recombination active complexes. For longer times these harmful complexes may be neutralized by a ‘regeneration’ called reaction. Supported by elevated temperatures, a conversion of the recombination active species into an inactive species is induced by the presence of charge carriers injected by light or bias voltages. In this contribution, the influence of light intensity and bias voltages is discussed.
Selection of Mobile ICT for Learning Informatics of Future Professionals in Engineering Pedagogy

The research aims to theoretically justify and experimentally verify selection of mobile ICT for learning informatics to future professionals in engineering pedagogy. The research tasks include selecting groups of informatics subjects and mobile ICT tools for learning future professionals in engineering pedagogy. The research object involves selection of mobile ICT for the training process. The re-search subject is selection of mobile ICT for learning informatics to future professionals in engineering pedagogy. The research results imply analysis of the national and foreign researches into mobile ICT for learning informatics. The latest publications concerning selection of mobile ICT for teaching Informatics subjects (Mobile Learning Management Systems, Mobile Modeling and Programming Environments, Mobile Database Management Systems, Mobile Multimedia Authoring Tools, Audience Response Systems) are analyzed. Informatics subjects are united into 19 groups, mobile ICT tools – into five groups. The experimental research is conducted according to the syllabuses for Speciality 015.10 “Professional Education (Computer Technologies)”. The expert assessment results for each of the content blocks of informatics subjects allow determining leading and auxiliary mobile ICT teaching tools.
A Recommender System for Informal Bibliotherapy

We present an online system that recommends web-based reading passages to users based on free long-form text-based elicitations of how they’re feeling right now. The system combines natural language processing techniques used to extract users’ intent with an information retrieval system to yield relevant and useful narratives for users. An eight week long user study found that most people who used the system reported better mood at the end of their interaction with the system. Interestingly, our study also discovered greater user engagement with randomly recommended narratives than with narratives selected for users based on their written descriptions of their own mental states. These observations could constrain the future design of self-help recommender systems.
The Effects of a 9-Week Hip Focused Weight Training Program on Hip and Knee Kinematics and Kinetics in Experienced Female Dancers

Abstract Increased involvement of the hip musculature during some movements is associated with enhanced performance and reduced injury risk. However, the impact of hip dominant weight training methods on movement strategy has seen limited attention within the literature. The aim of this study was to evaluate if a 9-week hip dominant weight training intervention promotes a more hip dominant movement strategy leading to an improvement in countermovement jump performance. Twenty-two experienced female dancers were recruited and separated into an intervention (age 24.4 ± 6.3 years, body height 165.5 ± 5.8 cm, body mass 65.9 ± 5.6 kg) and a control (age 22.9 ± 5.6 years, body height 163.3 ± 5.4 cm, body mass 57.4 ± 6.8 kg) group. The intervention group participated in a 9-week hip dominant training intervention, which consisted of a wide stance back squat, Romanian deadlift, hip thrusters, and a bent over row. Hip and knee kinematics and kinetics, and countermovement jump performance were assessed pre and post training. Significant interaction effects were found for peak hip joint moment (p = 0.030, η2 = 0.214) and countermovement jump performance (p = 0.003, η2 = 0.356), indicating an increase in peak hip joint moment and countermovement jump performance for the intervention group. Specifically, the intervention group showed a mean increase in jump height of 11.5%. The data show that the use of a hip dominant weight training strategy can improve hip contribution in the propulsion phase of the countermovement jump. Strength and conditioning specialists should incorporate hip dominant weight training exercises to increase hip strength and improve performance.
Clinical genetic testing and counselling in autism spectrum disorder

Abstract Autism spectrum disorders (ASDs) are phenotypically as well as genetically heterogeneous developmental disorders with a strong heritability. Clinical and basic science research has described many replicated genetic risk factors. Many findings can well be translated into clinical human genetic practice. The current article summarizes results of genetic studies in ASD, provides a diagnostic algorithm for the clinical human genetic work-up reflecting the German health care system options and gives information with regard to the obligatory genetic counselling after a clinical genetic assessment.
Genetics of Muscle Stiffness, Muscle Elasticity and Explosive Strength

Abstract Muscle stiffness, muscle elasticity and explosive strength are the main components of athletes’ performance and they show a sex-based as well as ethnicity variation. Muscle stiffness is thought to be one of the risk factors associated with sports injuries and is less common in females than in males. These observations may be explained by circulating levels of sex hormones and their specific receptors. It has been shown that higher levels of estrogen are associated with lower muscle stiffness responsible for suppression of collagen synthesis. It is thought that these properties, at least in part, depend on genetic factors. Particularly, the gene encoding estrogen receptor 1 (ESR1) is one of the candidates that may be associated with muscle stiffness. Muscle elasticity increases with aging and there is evidence suggesting that titin (encoded by the TTN gene), a protein that is expressed in cardiac and skeletal muscles, is one of the factors responsible for elastic properties of the muscles. Mutations in the TTN gene result in some types of muscular dystrophy or cardiomyopathy. In this context, TTN may be regarded as a promising candidate for studying the elastic properties of muscles in athletes. The physiological background of explosive strength depends not only on the muscle architecture and muscle fiber composition, but also on the central nervous system and functionality of neuromuscular units. These properties are, at least partly, genetically determined. In this context, the ACTN3 gene code for α-actinin 3 has been widely researched.
Plant growth of genotypes of Arabica coffee on water stress

Drought tolerant genotype has to be created due to changing of world climate. Performance of Arabica coffee offspring might be affected by parental environment. In North Sumatra province of Indonesia, Arabica coffee were growing at a wide range of elevation, precipitation and temperature. Hence, drought tolerant genotype might be available in this coffee plantation. The objectives of this research were to determine effect of water stress on performance Arabica coffee genotypes. Seven genotypes which were selected from seven different environments as well as four level of water treatments (100%, 75%, 50%, and 25% field capacity) were used. Paramaters were increment of plant height, stem diameter, and leaf number. Factorial experiment namely completely block design with two factors and three replications was conducted in the green house. The result revealed that interaction of genotype and level of water treatment was highly significant. Genotype Tobe2 seemed to be the most tolerant to water stress. Increment of leaf number of descendant had a negative significant correlation with minimum precipitation of parental environment. Increment of stem diameter of offspring positively significantly correlated with average temperature of parental environment. It could be concluded that it could be possible to carry out selection for drought tolerant genotype from the existing population of Arabica coffee. However, selection should be conducted in a controlled condition due to significant GxE interaction.
A COMPREHENSIVE CHARACTERIZATION OF GUELMOISE, A NATIVE CATTLE BREED FROM EASTERN ALGERIA

The present study was a global and a first characterization (Typology, biometric, biochemical and contribution on the genetic characterization) of the Guelmoise local cattle breed. A structured questionnaire surveys were carried out in 42 farms spread over the four wilayas of the north-eastern region of Algeria in order to characterize the local cattle population of Guelmoise and their mode of rearing. These surveys focused on the characteristics of the farms (socio-economic condition of the farmer, mode of breeding, reproduction and also to take samples of milk and blood). A total of 164 adult animals were selected for morphological description and body measurements (148 females and 16 males). The livestock system has an extensive nature and men are the main responsible for these farms. The height at withers (HaW), body length (BL), Heart Girth (HG), Spiral Tower (ST) and estimated weight (W) in Guelmoise cattle were 115 ± 0.07, 118 ± 0.08, 154 ± 0.09, 187 ± 0.11 cm and 258 , 12 ± 43.12 kg respectively in females and 171 ± 0.16, 176 ± 0.18, 187 ± 0.08, 225 ± 0.08 cm and 462 ± 59.67 kg respectively in males. Multivariate statistical analyses have allowed identifying four different classes were defined as follows morphometric measurements, weight and age in females as in males. Estimated age at first calving was 39.40 months while the calving interval varies between 14 to17 months and the reproductive life of the cows (13,7 years). The average daily production of milk 5,55 ± 1,67 liters in spring with a duration of lactation varies between 6 to 7 month. The physico-chemical characteristics of milk were focused on the Fat content (FC), Protein content (PC), Lactose (Lact), Dry extract (DE), Defatted dry extract (DDE) and freezing point depression (FPD) were respectively 2.85 ± 0.89%, 3.60 ± 0.39%, 4.82 ± 0.13%, 11.84 ± 0.90%, 9.13 ± 0.41% and 0.56 ± 0,01°C. The genotyping of 24 individuals of the Guelmoise population using the Illumina BovineSNP50 BeadChip, we found that the observed heterozygosity was globally equivalent to 0.30. The inbreeding measured by Fis was slightly positive (~0.04) indicating the absence of a phenomenon of selection. The data contribute to the feasibility of a conservation and selection programme for this breed and the results are useful for the implementation of a conservation strategy that should aim to conserve animals. The Guelmoise cattle can be used as an alternative genetic resource for production improvement programs.