Miracle-dz/UniFAR-FTUs huggingface dataset:
Lansoprazole plus levosulpiride versus esomeprazole in participants with gastroesophageal reflux disease and erosive esophagitis: a double blinded randomized control trial

Aim: The aim was to compare the efficacy and safety of lansoprazole plus levosulpiride over esomeprazole. Methodology: This randomized control trial recruited 1000 participants having symptomatic gastroesophageal reflux disease (GERD) and erosive esophagitis and they were blindly randomized into two groups in a 1:1 ratio with appropriate concealment. Group 1 was given lansoprazole plus levosulpiride combination twice daily whereas group 2 was prescribed only esomeprazole twice daily. The primary efficacy endpoint was the healing of erosive esophagitis and GERD at week 49. Secondary assessments included improvement in quality of life. Participants’ quality of life was assessed before starting the treatment and post-treatment using a short-form health survey questionnaire (SF-36). Results: The lansoprazole plus levosulpiride group had significantly lower rates of positive postintervention GERD and erosive esophagitis status, and higher rates of sustained resolution of heartburn compared to the esomeprazole alone group. However, the lansoprazole plus levosulpiride group also had a higher risk of nausea. Conclusion: Lansoprazole plus levosulpiride is a more effective and safe treatment for GERD than esomeprazole alone. Participants in the lansoprazole plus levosulpiride group showed a significantly higher rate of sustained resolution of GERD, lower rates of postintervention GERD and erosive esophagitis status, and a higher incidence of nausea compared to the esomeprazole alone group. Although quality of life worsened in both groups, adverse effects did not significantly differ. These findings strongly support the use of lansoprazole plus levosulpiride as a preferred treatment option for GERD and erosive esophagitis, which could have significant clinical implications for managing this common condition.
Intrathecal Catheter for Chemotherapy in Leptomeningeal Carcinomatosis From HER2-Negative Metastatic Breast Cancer

Purpose Most oncological treatments for leptomeningeal metastasis (LM) do not cross the blood-brain barrier (BBB). One therapeutic option is intrathecal (IT) chemotherapy. Both the brain-implanted Omaya reservoir and lumbar puncture (LP) are classic routes for IT chemotherapy delivery. An intrathecal catheter (IC) connected to a subcutaneous port is a recently developed option for the management of chemotherapy infusions. It is essential to evaluate the efficacy and safety of chemotherapy infusion using such device. Methods We conducted a retrospective monocentric study within Institut de cancerologie de l’Ouest at Angers, including all patients with advanced breast cancer (aBC) with LM implanted with an IT device for IT chemotherapy between January 2013 and May 2020. The primary endpoint was overall survival (OS) and secondary endpoints included surgical feasibility, patient safety, and progression-free survival (PFS). The catheter was inserted through an LP, the tip was positioned at the right level and connected to a subcutaneous port implanted under the skin of the anterior thoracic wall. IT chemotherapy is painless and easy for qualified nurses to administer on an outpatient basis. Results Thirty women underwent the implantation. No failures occurred during the procedure. A total of 77% of patients reported no complications after implantation. Only three complications required surgical treatment. The median number of IT chemotherapy courses per patient was 8 (range, 2–27). The tolerance profile for iterative IT chemotherapy was manageable in ambulatory care. With a median follow-up of 76.5 months (95% confidence interval [CI], 11.6–not available), the median OS was 158 days (95% CI, 87–235), and the median PFS was 116 days (95% CI, 58–174). Conclusion Infusing chemotherapy using an implanted catheter is an efficient option for managing IT chemotherapy with a good tolerance profile. Patient-reported outcomes for the evaluation of IT chemotherapy toxicity are currently being developed.
Effect of Different Roughage Sources in Fermented Total Mixed Ration and Energy Intake on Meat Quality, Collagen Solubility, Troponin T Degradation, and Fatty Acids of Native Thai Cattle Longissimus Muscle

The effects of roughage sources in the fermented total mixed ration (FTMR) and the level of energy intake on meat quality, collagen solubility, and troponin T degradation in longissimus thoracis (LT) muscle of native Thai cattle (NTC) were investigated. Results showed that roughage source affected fatty acid composition in the LT muscle (p < 0.05), as NTC fed Pakchong 1-Napier-based FTMR had higher monounsaturated fatty acid content and ω 6:ω 3 ratio. The high-energy ad libitum group had lower drip loss, lower shear force, and higher percent collagen solubility (p < 0.05). However, energy intake had no effect on troponin T degradation and fatty acid composition (p > 0.05). Longer aging of 14 days showed lower shear force values, higher collagen solubility, and troponin T degradation rate but higher cooking loss (p < 0.01). In conclusion, the meat quality of NTC could be improved by ad libitum feeding with NG-FTMR, as their meat had higher MUFA content, lower drip loss, lower shear force, and higher collagen solubility. In addition, the tenderness of NTC meat could be further improved by longer aging of 14 days post-mortem.
Public debt and economic growth in sub-Saharan Africa: Nonlinearity and threshold effects

Abstract Most studies on the effects of debt on growth, particularly following the global financial crisis, have focused mainly on the advanced and emerging countries. Our focus on sub-Saharan Africa (SSA) derives from the recent experience of slow growth at a time of rising debt in the sub-region. This approach allows us the opportunity to fit a model that accounts for some region-specific characteristics, such as the quality of institutions and policies, conflict, and adverse terms of trade shocks. Our dataset comprises 24 SSA countries spanning 39 years from 1980 to 2018. We employ a variety of panel estimation techniques suitable for addressing the problems of endogeneity and cross-section dependence. The fixed effects instrumental variable technique is used as the baseline technique, while the bias corrected least-squares dummy variable and the limited information maximum likelihood are used for robustness. In agreement with recent literature, we find compelling evidence in support of a nonlinear relationship between debt and growth, which suggests that public debt may become harmful to growth if it rises beyond a certain level. Further to that, the evidence presents a threshold estimate of 78–85% in most cases. Some variations in threshold estimates based on differences in empirical estimation techniques were observed, which point to the need to localize debt–growth studies to country-specific cases for more applicable results. Policy implications based on these findings are discussed.
Ecology and silviculture of poplar plantations.

D.I. ; Isebrands, J.G. ; Eckenwalder, J.E. ; Richardson, J., eds. Poplar culture in North America, part A, chapter 5. Ottawa: NRC Research Press, National Research Council of Canada: 153-206. ABSTRACT. Poplars are some of the fastest growing trees in North America and foresters have sought to capitalize on this potential since the 1940s. Interest in growing poplars has fluctuated, and objectives have shifted between producing sawlogs, pulp-wood, or more densely spaced "woodgrass" or biofuels. Currently, most poplar plantations are established for pulpwood or chip production on rotations of 10 years or less, but interest in sawlog production is increasing. Sid McKnight characterized cottonwood as a prima donna species: under ideal conditions, growth rates are just short of spectacular. Just as this can be applied to all poplars, it is equally true that all poplars are demanding of good sites and careful establishment. Growing poplars in plantations is challenging, and good establishment the first year is critical to long-term success. If a grower lacks the commitment or resources to provide needed treatments at critical times, then species other than poplars should be considered. Our objective in this chapter is to provide growers with current information for establishing and tending poplar plantations, as practicedmore » in North America. Where we have sufficient information, differences between the poplar-growing regions of the United States and Canada will be noted. Mostly information is available on eastern and black cottonwood and their hybrids. « less
Spectral discrimination and classification of sugarcane varieties using EO-1 hyperion hyperspectral imagery

The genetic variety of sugarcane is a major factor in many aspects of sugarcane production. It can control growth rates, yield, sugar content, and resistance or susceptibility to pest and diseases. Thus, reliable auditing of the varieties grown in different areas is necessary for profitable sugarcane cropping. The specific objectives of this study were: a) to assess the spectral separability of different sugarcane varieties, b) to determine which plant attributes will provide the potential discriminating features, and c) to assess the accuracy of image classification to map sugarcane varieties. Using an atmospherically corrected EO-1 Hyperion image acquired over Mackay, Queensland, Australia, the apparent reflectance signatures from sample areas of sugarcane varieties were analysed using discriminant analysis (DA) to explore spectral separability and to determine the optimum bands and indices. Five and eight cane varieties were separately used for each DA run. Then, image classification was implemented for eight cane varieties using four selected classification algorithms. These were independently performed for: a) 152 individual Hyperion bands, and b) a selection of 20 spectral vegetation indices. From the discriminant analysis, the classification results indicate a high discrimination between cane varieties, i.e. 97% accuracy for five varieties and 74% for eight varieties. The best indices for discrimination were OSAVI, TCARI, Ratio 770/550, Pigment Specific Simple Ratio (Chlorophyll b) and Simple Ratio 800/550, indicating that pigments and the leaf internal structure were relevant in the discrimination. However, for the classification of the entire image, the results were not encouraging; the highest classification accuracy was only 46%. The low accuracy can be attributed to the high number of classes used (i.e. eight cane varieties) and the many confounding factors pertaining to crops, management regime, growth stage, and background features such as soils. Thus, future approaches should consider the integration of non-image information (e.g. soil information, crop calendar, etc.) and/or exploring the usefulness of other measurable plant attributes (e.g. leaf/canopy geometry).
GEOspace X-ray imager (GEO-X)

Abstract. GEOspace X-ray imager (GEO-X) is a small satellite mission aiming at visualization of the Earth’s magnetosphere by X-rays and revealing dynamic couplings between solar wind and the magnetosphere. In-situ spacecraft have revealed various phenomena in the magnetosphere. X-ray astronomy satellite observations recently discovered soft X-ray emissions originating from the magnetosphere. We are developing GEO-X by integrating innovative technologies of a wide field of view (FOV) X-ray instrument and a small satellite for deep space exploration. The satellite combines a Cubesat and a hybrid kick motor, which can produce a large delta v to increase the altitude of the orbit to about 30 to 60 RE from a relatively low-altitude (e.g., geo transfer orbit) piggyback launch. GEO-X carries a wide FOV (5 × 5 deg) and a good spatial resolution (10 arcmin) X-ray (0.3 to 2 keV) imaging spectrometer using a micro-machined X-ray telescope and a CMOS detector system combined with an optical blocking filter. We aim to launch the satellite around the solar maximum of solar cycle 25.
Parenting stress and associated factors in healthcare workers after the second wave of COVID-19 in India: a two-center cross-sectional study

Background High parenting stress (PS) in members of the general population during the COVID-19 pandemic was exacerbated by work-, family-, and child-related factors. However, the negative effects of PS on the mental health and work participation of healthcare workers (HCWs) have received limited attention. This study aimed to examine the proportion of severe PS among HCWs and identify its contributory factors. Methods This cross-sectional survey was conducted in two COVID-19-care hospitals attached to medical colleges in India between November 1 and December 24, 2021, following the delta variant-driven second wave of COVID-19. The study recruited 662 HCW parent and child dyads (aged 1.5–18 years) and assessed workplace, family, and child-related characteristics. The Parenting Stress Scale (PSS) and Child Behavior Checklist (CBCL) were used to identify severe PS and child behavioral issues, respectively. Univariable and multivariable logistic regression analyzes were used to identify the significant and independent risk factors associated with severe PS, respectively. Results Equal proportions of medical and paramedical HCWs completed the survey [mean age: 36.96 ± 5.89; female: 466 (70%)]. The median PSS score of HCWs was 33 [interquartile range (IQR): 28–39], and 23% (155/662) of the HCW parents experienced severe PS. The independent predictors of severe PS included the female sex [adjusted odds ratio (aOR): 3.31; 95% confidence interval (CI): 1.74–6.29], HCWs with >15-day postings in COVID-19 care (aOR: 3.74; 95% CI: 1.53–9.16), having children with behavioral issues (aOR: 3.49; 95% CI: 1.29–9.48), HCWs at the Dehradun center (aOR: 2.25; 95% CI: 1.24–4.10), having an HCW spouse simultaneously working in COVID-19 care (aOR: 1.88; 95% CI: 1.01–3.49), and HCWs with joint families (aOR: 1.93; 95% CI: 1.17–3.18). Conclusion Overall, 23% of the cohort of HCWs continued to experience severe PS after the second COVID-19 wave driven by the delta variant in India. Routine screening of HCWs for PS using the PSS or similar measures, anticipatory guidance for parenting, and targeting at-risk HCWs with appropriate supportive measures may help reduce the incidence of severe PS and optimize the participation of HCWs in the fight against current and future pandemic-like situations.
La tectonique hercynienne dans l'Est du Maroc

Ce travail est une presentation de l'histoire sedimentaire et de 1’evolution tectonometamorphique de la partie orientale de la chaine hercynienne du Maroc qui affleure dans les boutonnieres de la Meseta orientale (Debdou, Mekam, Midelt, Chaine des Horsts) et des chaines atlasiques (Tazekka, Boudoufoud, Beni-Snassene, Mougueur, Tamlelt). La premiere partie decrit les series stratigraphiques. Du Cambro-Ordovicien au Siluro-Lochkovien, cette partie de la chaine ne se distingue guere du reste du Maroc. Au Devonien, par contre s'individualise un bassin accueillant des depots de type flysch. Le Carbonifere est discordant sur les terrains plus anciens structures par une phase eovarisque, il est essentiellement caracterise par des depots volcano-sedimentaires associes a un magmatisme calce-alcalin. La deuxieme partie concerne l’evolution tectono-metamorphique qui comprend deux phases principales. 1) La phase eovarisque ou ante-viseenne anterieure aux depots volcano-sedimentaires du Viseen. Des deformations synschisteuses (D1 + D2) enchainent plissement + cisaillement a vergence Ouest, dans un climat de metamorphisme anchi a epizonal ; elles sont suivies par des ecaillages dans un niveau structural superficiel. Des datations isotopiques montrent qu'il est possible de distinguer un episode a 370 MA (phase bretonne) et un episode a 330 MA (phase sudete), ce dernier permettant des correlations avec l'Est du Maroc Central. 2) La phase post-westphalienne ou tardivarisque (D3) est representee par des structures relativement simples : plis N50-90 droits ou a vergence variable, avec schistosite de fracture. La mise en place de granitoides syn a tardi-tectoniques acheve l’evolution hercynienne. La troisieme partie replace la region etudiee dans l'ensemble de la chaine hercynienne d'Afrique du Nord dont elle represente la zone la plus interne. Les correlations avec les segments voisins sont envisagees, elles font ressortir la position privilegiee du Maroc, sur une zone de coulissement en bordure du Gondwana.
Measuring children’s work in South Asia: Perspectives from national household surveys

The Report is based on recent information from national household surveys in seven of the eight South Asian countries (i.e. Bangladesh, Bhutan, India, Nepal, the Maldives, Pakistan, and Sri Lanka), and provides an overview of the nature and extent of child labour, children’s employment and educational status, at both the South Asian regional level and in each of the seven countries. For Afghanistan, a brief profile of child labour in the country has been compiled from various studies. Gender dimensions are explored, as are the differences between rural and urban areas. The Report highlights gaps and inconsistencies between national statistical surveys, which limited the analysis and subsequent findings. It includes recommendations for action, both at national level and at the SAARC (the South Asia Association for Regional Cooperation) level.
Biology Teachers’ Perspective on Change of Curriculum Policy: A Case for Implementation of “Independent” Curriculum

Curriculum change is one way of adapting education in the face of various scientific and technological developments. These changes lead to different views from numerous educational actors, one of which is teachers. This study aims to explore biology teachers' perspectives on curriculum change in Indonesia. A qualitative phenomenological study with semi-structured interviews explored the biology teachers' perspectives. The interview results were analyzed using the thematic analysis method with ATLAS.ti 22 software to determine themes. The results showed four themes from biology teachers' perspectives on curriculum change, which are (1) the factors affecting independent curriculum implementation; (2) the teachers' concerns; (3) the teachers' efforts; (4) the support systems needed by teachers. Biology teachers' perspectives show that teachers experience various problems and concerns but still strive to implement learning according to the curriculum. Synergistic support from schools, colleagues, government, educational colleges, and parents of students is needed for the successful implementation of an independent curriculum.
Assessing the Parameterization of RADARSAT-2 Dual-polarized ScanSAR Scenes on the Accuracy of a Convolutional Neural Network for Sea Ice Classification: Case Study over Coronation Gulf, Canada

Abstract Arctic amplification has many impacts on sea-ice extent, thickness, and flux. It becomes critical to monitor sea-ice conditions at finer spatio-temporal resolution. We used a simple convolutional neural network (CNN) on the RADARSAT-2 dual-polarized ScanSAR wide archive available over Coronation Gulf, Canada, to assess which SAR parameter improves model performances to classify sea ice from water on a large volume of data covering 11 years of ice and surface water conditions. An overall accuracy of 90.1% was achieved on 989 scenes of 100% ice cover or ice-free conditions. An accuracy of 86.3% was achieved on the last year of data (134 scenes) which was kept out of the training process to test the model on an independent dataset. A better accuracy is obtained at lower incidence angles and the HH polarization provides the most information to classify ice from water. To achieve the best accuracy, the incidence angle and the noise equivalent sigma-nought had to be included as input to the model. A comparison done with the ASI passive microwave product shows similar errors in total sea ice concentration when using the Canadian Ice Service regional charts as reference. Nonetheless, errors from both datasets differ and the CNN outputs show greater potential to reduce masked areas, given the better spatial resolution, enabling data classification closer to land and identify features not captured by the ASI dataset.
The Fossil Record of Iteaceae and Grossulariaceae in the Cretaceous and Tertiary of the United States and Canada

Fossilized flowers and fruits from the Upper Cretaceous (Turonian, ca. 90 my before present) Raritan Formation of New Jersey are described as the new genus Divisestylus with two species, D. brevistamineus and D. longistamineus. The fossils are fusainized and three-dimensionally preserved. Morphological characteristics suggest affinities with extant Saxifragaceae and Iteaceae, two closely related families in Saxifragales. Similarities include a pentamerous perianth, calyx fused below into a hypanthium with free sepal lobes above, haplostemonous androecium with stamens situated opposite the calyx lobes, inferior ovary, bicarpellate gynoecium, numerous ovules on axile placentas, conspicuous intrastaminal nectary ring, and capsulate fruit opening apically. The unique fusion of the gynoecium, with carpels and stigmas fused but styles free, indicates closer affinities with extant Iteaceae, whereas other characters, such as basifixed anthers in D. brevistamineus, tricolpate, striate pollen grains, and anomocytic stomata, indicate closer affinities to Saxifragaceae. Cladistic analyses utilizing molecular data from a previously published analysis and morphological data as well as morphological data alone demonstrate the fossils share a more recent common ancestor with Iteaceae than Saxifragaceae, thereby making Divisestylus the oldest fossils known with clear affinities to Iteaceae. 2
Accountability And Internal Control Systems On The Quality Of Regional Equipment Organizational Reports With Organizational Commitment As Moderation

Purpose: This study aims to examine the effect of accountability and internal control systems on thequalityof financial reports of regional apparatus organizations with organizational commitment as moderation. Methodology/approach: Collecting data in this study using a questionnaire. Questionnaires were distributed as many as 120 questionnaires which were distributed to 20 OPD in Bantul Regency. A total of 95 questionnaires were filled out and returned to the authors for analysis. This research is included into quantitative research. The sample in this study used purposive sampling. The analytical tool used in this study is multiple linear regression with the IBM SPSS Statistics 22 application. Findings: The results of this study indicate that accountability has a positive and significant effect on the quality of financial statements of local government organizations, the internal control system has a positive effect on the quality of financial reports and the internal control system has a positive and significant effect on the quality of financial reports and is moderated by organizational commitment. Practical implications: Future will improve accountability performance of a government agency so that the government can provide information to the public in the form of quality financial reports. Originality/value: Accountability has a role to describe the success or failure of an organization's mission to achieve predetermined goals and indicators in the form of local government financial reports.