Miracle-dz/UniFAR-FTUs huggingface dataset:
Application of GGE biplot analyses for characterizing diverse sesame (Sesamum indicum) germplasm for yield and yield-contributing traits

A representative sample of 146 diverse sesame accessions, originating from 26 countries and assigned into six groups on the basis of their eco- geographical origin, was characterized for yield and yield-contributing traits using “GGE biplot analyses”. ‘Which-won-where’ application of GGE biplot was used to rank accessions of each group on the basis of collective trait contributions to individual accession. Eighteen promising accessions having combination of positive traits (PI 202722Myanmar, PI 223713India, PI 220664Afghanistan, PI 285173Israel, PI 165021Turkey, PI 170711Turkey, PI 490063South Korea, PI 490033South Korea, PI 345669Soviet Union, PI 561705Mexico, PI 594909Mexico, PI 280790United States, PI 198155Egypt, PI 189081Cameroon, PI 246386Zaire, Pragati India, SVPR 1India, ACHBB 97India) were identified. Correlation coefficient analysis (GGE biplot) as carried out over two years, revealed that total pods/plant (r=0.453**, 0.24**), pods on main shoot (r=0.337**, 0.492**) and seeds/pod (r=0.268**, 0.254**) were the main yield-contributing traits in sesame. Per cent oil content/protein content had no inverse relationship with yield which makes it possible to combine high yield and high oil content in sesame cultivars. A select group of accessions (24) were also compared for stability of performance over two years. Altogether changed ranking was observed for majority of the accessions during second year indicating their differential genonotype × environment response; however one accession PI 223713 was identified which was stable for high yield and yield contributing traits across two years.
Effects of Vitamin A and β-Carotene on Reproductive Performance in Gilts1

The effects of vitamin A and beta-carotene on various reproductive parameters were examined in 108 crossbred gilts. Gilts were fed a diet free of vitamin A and beta-carotene for 5 wk, then assigned to one of eight treatments. Statistical comparisons were performed on three sub-groupings of these treatments as follows: (1) DEFICIENT (received 2,100 IU of vitamin A X head-1 X d-1, (2) FED (received dietary supplementation of 0, 2,100 or 12,300 IU vitamin A and (or) 0, 32.6 or 65.2 mg beta-carotene X head-1 X d-1) or (3) INJECTED (received injection supplementation of 0 or 12,300 IU vitamin A and 32.6 mg beta-carotene X head-1 X d-1, administered once weekly). Gilts remained on treatment through weaning of litters at 21 d postpartum. Plasma vitamin A and beta-carotene levels were greatly elevated in INJECTED gilts. Concentrations of these compounds in plasma were similar between DEFICIENT and FED gilts. There was no treatment difference in number of corpora lutea/gilt. Embryonic mortality was lowest (P less than .01 to .02) in INJECTED gilts (14 +/- 3%) compared with DEFICIENT (29 +/- 5%) or FED (25 +/- 3%) gilts. Baby pig mortality averaged 6 +/- 1% and was not different among treatments. INJECTED gilts had more (P less than .05 to .01) piglets/litter at birth and at weaning (9.5 +/- .3 and 9.0 +/- .3 piglets/litter, respectively) than DEFICIENT (7.9 +/- .5 and 7.6 +/- .5 piglets/litter) or FED gilts (8.7 +/- .3 and 8.1 +/- .3 piglets/litter). (ABSTRACT TRUNCATED AT 250 WORDS)
Morphological changes associated with Nile crocodile (Crocodylus niloticus) phallic glans inflation

The crocodylian phallic glans is the distal inflatable structure that makes the most direct contact with the female cloacal and associated reproductive tract openings during copulation. Therefore, its form and function directly impact female tissue sensory interactions and insemination mechanics. Compared to mammals, less is known about glans functional anatomy among other amniotes, including crocodylians. Therefore, we paired an ex vivo inflation technique with magnetic resonance imaging 3D‐reconstructions and corresponding histological analyses to better characterize the morphological glans restructuring occurring in the Nile crocodile (Crocodylus niloticus) at copulation. The expansion of contiguous inflatable spongiform glans tissues is variably constrained by adjacent regions of dense irregular collagen‐rich tissues. Therefore, expansion shows regional differences with greater lateral inflation than dorsal and ventral. Furthermore, this enlargement elaborates the cup‐like glans lumen, dorsally reorients the glans ridge, stiffens the blunt and bifid glans tip, and putatively works to seal the ventral sulcus spermaticus semen conduit groove. We suggest how these dynamic male structures may interact with structures of the female cloacal urodeum and how these morphological changes, in concert with the varying material properties of the structural tissue compartments visualized in this study, aid copulatory gamete transfer and resulting fecundity.
The stock structure of northern and western Australian Spanish mackerel

This study investigated the use of stable δC and δO isotopes in the sagittal otolith carbonate of narrow-barred Spanish mackerel, Scomberomorus commerson as indicators of population structure across northern and western Australia. Discrete location-specific stable isotope signatures were evident among adult assemblages of S. commerson across northern and western Australia. These discrete location-specific signatures indicate that fish from a number of sites sampled across northern and western Australia (Cervantes-Abrolhos Islands, Shark Bay­ Exmouth-Thevenard Island, Port Hedland, Eighty Mile Beach, Lord Mayor Shoal-Barcoo Shoal, White Island-Rob Roy Reef, Bassett-Smith Shoal, Fog Bay, Flat Top Bank-Cape Van Diemen-Cape Wessel, Groote Eylandt, Sir Edward Pellew Group, Mornington Island, Lost City, Weipa-Torres Strait, Cairns, Townsville) and from Indonesia (Kupang) are significantly different. The significant differences in the isotopic signatures of S. commerson demonstrate that there is unlikely to be any substantial movement of fish among these spatially discrete adult assemblages. A lack of temporal variation between sampling dates in otolith isotope ratios among those locations for which replicate samples are available indicates that S. commerson do not undergo longshore spatial shifts in distribution during their life history. Furthermore, the persistence through time of several of these spatially explicit stable isotopic signatures indicates that at these spatial scales the population units sampled comprise functionally distinct independent management units or separate ‘stocks’ for many of the purposes of fisheries management. However, these location-specific isotope signatures do not preclude the possibility of inshore-offshore movements or cycling during the life history of S. commerson. The persistent spatial structure present among populations of S. commerson across northern and western Australia indicates that it may be advantageous to consider S. commerson population dynamics and fisheries management from a meta-population perspective.
Morbidity and drug prescribing patterns at a rural primary health care center of Bangladesh

Background and objectives: World Health Organization (WHO) and the National Health Policy of Bangladesh have repeatedly been emphasizing on the use of essential drugs prescribed by generic names. The prescription monitoring studies provide a bridge between areas like rational use of drugs and evidence based medicine. Knowledge on distribution and burden of diseases in a community is essential for planning rational use of drugs in a community. The present study tried to determine the morbidity profile and drug prescribing practices of healthcare providers in a rural primary health care. Methods: The study was conducted at a rural health center located 50 Km north of capital city Dhaka. A semi-structured questionnaire was used for collecting data on socio-demographic conditions, clinical complaints and types of drugs prescribed. WHO prescribing indicators was used to find out the drug prescribing pattern. Results: A total of 583 patients were enrolled. Problems related to respiratory system (21.1%), musculoskeletal system (17.3%) and skin diseases (11.1%) were common reasons for visiting health centre. Oral drugs were prescribed with highest proportion (96.1%). More than half (62.6%) of the drugs were prescribed from essential drug list. About half (49.1%) were antibiotics and 45.6% of the drugs were prescribed in their generic name. Anti-microbial (64.5%), anti-peptic ulcer (43.1%) and NSAIDs (42.5%) were most frequently prescribed. Out of five WHO core prescription indicators, four were below the acceptable values. Conclusion: The study demonstrated that there is an urgent need to promote rational use of drugs among the healthcare providers. IMC J Med Sci 2018; 12(2): 50-56
The Lived Experience of Postpartum Depression: A Review of the Literature

Abstract Postpartum depression has been studied from a variety of perspectives and by many disciplines. The aim of this article is to review qualitative literature exploring the first-person accounts of women diagnosed with postpartum depression and highlight the absence of work in madness discourse. Searches of multiple databases (Cumulative Index to Nursing and Allied Health Literature, Sociological Abstracts, Sociology Database, Web of Science, Genderwatch, PILOTS, MedLine from PubMed, PsycINFO) were undertaken. There is a significant gap in literature that exists in relation to the lived experience of women diagnosed with postpartum depression who do not identify as mentally ill.
Endoscopic Ultrasound-Guided Biliary Drainage with a Fully Covered Self-Expandable Metal Stent for Malignant Obstructive Jaundice

Objective: To study the therapeutic effect of Endoscopic ultrasound-guided biliary drainage (EUS-BD) with a nitinol fully covered self-expandable metal stent in patients with malignant obstructive jaundice when endoscopic retrograde cholangiopancreatography (ERCP) fails. Methods: From January 2016 January 2018, all patients with malignant obstructive jaundice during hospitalization underwent EUS-guided biliary drainage with a nitinol fully covered self-expandable metal stent, and the operation success rate, the clinical success rate, complications, length of hospital stay and survival time were observed. Results: Of 36 patients, 34 cases had successful operation; the operation success rate was 94.44% (34/36). The clinical success rate was 88.89% (32/36). Hemobilia occurred in 1, acute cholangitis in 1, and bile peritonitis in 1; improved after conservative treatment, the complication rate is 8.33% (3/36). Hospital stay and survival time was 21.54 ± 4.73 days and 220.54 ± 54.76 days, respectively. Conclusion: EUS-BD with a nitinol fully covered self-expandable metal stent may be a feasible and effective treatment option in patients with malignant biliary obstruction when ERCP fails.
Analyzing Privacy Practices of Existing mHealth Apps

: Given students’ reliance on smartphones and the popularity of mobile health apps, care should be taken to protect students’ sensitive health information; one of the major potential risks of the disclosure of this data could be discrimination by insurance companies and employers. We conducted an exploratory study of 197 existing smartphone apps, which included 98 mobile health apps, to study their data collection, usage, sharing, storage and deletion practices. We present our ﬁndings from the analysis of privacy policies and permission requests of mHealth apps, and propose the need for a usable health data dashboard for users to better understand and control how their health data is collected, used, shared and deleted.
The Ecology and Life History of the Endangered Snail Darter, Percina (Imostoma) tanasi Etnier

A 2-year s tudy of the eco l o gy and l i fe h i story of the s na i l darter , Percina tanasi, was conducted from 1974 to 1976 . The s na i l darter wa s found to be a s tri c t l y benth i c s pec i es pri n c i pa l l y a s soc i ated wi th a l arge r i ver g rave l shoa l ha b i ta t where i t feeds and reproduces . I ts present ra nge i s restri c ted to the l ower L i tt l e Tennessee R i ve r and a sma l l adjacent porti on of t h e Tennes see R i ver . I t i s s pec u l a ted that P. tanasi once occu p i ed a much wi der range i n the upper Tennes see R i ver drai nage wh i ch has s i nc e been curta i l ed by i mpoundmen ts . Th i s s pec i es wa s found to be a s hortl i ved darter whi c h , a l ong wi th other members of the s u bgenus Imos toma, s pawn s i n mi d-wi nter . Larval dri ft i s a s i gn i f i cant event i n the l i fe of the s na i l darter , and earl y devel o pment i s very s l ow . Adu l ts are mi gratory , e s pec i a l l y dur i n g the breed i ng season . The pri nc i pa l d i et con s t i tuents are gas tropods ; there i s some u t i l i za t i o n of i n sects . A h i gh degree of s e l ect i v i ty i s ex­ erc i s ed i n procuri n g the gas tro pod d i et , and there a re seasona l trends i n both d i et compo s i t i on and consumpt i on l evel s . P. tanasi occu p i e s a remote pos i t i on i n the L i ttl e Tennessee food web . Preda t i o n i s thought to be h i g h on the eggs and l arval s tages of P. tanasi but l ow on adu l ts . Paras i t i sm i s very l ow . The present ecol og i ca l s i tuati on of the s na i l darter i s thought to be cons i dera b l y a l tered from that o f pre i mpoundmen t days . I t i s threatened w i th ext i nct i on i f the rema i nder of i ts hab i tat i s i nundated by the Tel l i co Dam .
Opinion: Why carbon pricing is not sufficient to mitigate climate change—and how “sustainability transition policy” can help

Carbon pricing is often presented as the primary policy approach to address climate change. We challenge this position and offer “sustainability transition policy” (STP) as an alternative. Carbon pricing has weaknesses with regard to five central dimensions: 1) problem framing and solution orientation, 2) policy priorities, 3) innovation approach, 4) contextual considerations, and 5) politics. In order to address the urgency of climate change and to achieve deep decarbonization, climate policy responses need to move beyond market failure reasoning and focus on fundamental changes in existing sociotechnical systems such as energy, mobility, food, and industrial production. The core principles of STP can help tackle this challenge. Many are eager to take more substantive policy steps to address climate change, but pricing carbon pricing alone won’t be sufficient. Image credit: Shutterstock/Shawn Goldberg. Realizing deep decarbonization at the pace necessary to mitigate the worst impacts of climate change has emerged as a pressing challenge for policymakers (1). As a result, the debate about appropriate policy responses has intensified. Many experts and societal actors see carbon pricing as the primary way forward (2⇓–4). Some even use it to argue against other policies, such as fuel efficiency standards. Viewed as the most efficient approach to cut greenhouse gas (GHG) emissions, carbon pricing incentivizes actors to seek the lowest-cost abatement options for their specific circumstances. Consequently, many economists argue that carbon pricing should be the cornerstone of a climate policy response. We question this reasoning. Carbon pricing faces five major issues that limit its use for accelerating deep decarbonization. First, carbon pricing frames climate change as a market failure rather than as a fundamental system problem. Second, it places particular weight on efficiency as opposed to effectiveness. Third, it tends to stimulate the optimization of existing systems rather than transformation. Fourth, it … [↵][1]1To whom correspondence may be addressed. Email: daniel.rosenbloom{at}utoronto.ca. [1]: #xref-corresp-1-1
A minimum dataset for a standard adult transthoracic echocardiogram: a guideline protocol from the British Society of Echocardiography

There have been significant advances in the field of echocardiography with the introduction of a number of new techniques into standard clinical practice. Consequently, a ‘standard’ echocardiographic examination has evolved to become a more detailed and time-consuming examination that requires a high level of expertise. This Guideline produced by the British Society of Echocardiography (BSE) Education Committee aims to provide a minimum dataset that should be obtained in a comprehensive standard echocardiogram. In addition, the layout proposes a recommended sequence in which to acquire the images. If abnormal pathology is detected, additional views and measurements should be obtained with reference to other BSE protocols when appropriate. Adherence to these recommendations will promote an increased quality of echocardiography and facilitate accurate comparison of studies performed either by different operators or at different departments.
Neurourology and Urodynamics

Department of Urogynaecology, St. George Hospital, School of Women's and Children's Health, University of New South Wales, Sydney, Australia Department of Clinical Pharmacology and Toxicology, St. Vincent's Hospital, Sydney, Australia St. Vincent's Clinical School, University of New South Wales, Sydney, Australia Department of Clinical Chemistry and Endocrinology, New South Wales Health Pathology East, Prince of Wales Hospital, Sydney, Australia
The Influence of Opioid Use Disorder on Open Reduction and Internal Fixation Following Ankle Fracture

Background. Ankle fractures are common and may require open reduction and internal fixation (ORIF). Literature is scarce evaluating the associations of opioid use disorder (OUD) with ORIF postoperative outcomes. This study investigates whether OUD patients have increased (1) costs of care, (2) emergency room visits, and (3) readmission rates. Methods. ORIF patients with a 90-day history of OUD were identified using an administrative claims database. OUD patients were matched (1:4) to controls by age, sex, and medical comorbidities. The Welch t-test determined the significance of cost of care. Logistic regression yielded odds ratios (ORs) for emergency room visits and 90-day readmission rates. Results. A total of 2183 patients underwent ORIF (n = 485 with OUD vs n = 1698 without OUD). OUD patients incurred significantly higher costs of care compared with controls ($5921.59 vs $5128.22, P < .0001). OUD patients had a higher incidence and odds of emergency room visits compared with controls (3.50% vs 0.64%; OR = 5.57, 95% CI = 2.59-11.97, P < .0001). The 90-day readmission rates were not significantly different between patients with and without OUD (8.65% vs 7.30%; OR = 1.20, 95% CI = 0.83-1.73, P = .320). Conclusion. OUD patients have greater costs of care and odds of emergency room visits within 90 days following ORIF. Levels of Evidence: Level III: Retrospective cohort study
Pediatric Pulmonology

Funding information Project funded by China Postdoctoral Science Foundation, Grant/Award Number: Postdoc no. 241006; Science and Technology Planning Project 2019 of the Bureau of Science and Technology of Foshan City, Grant/Award Number: 1920001000338; Science and Technology Planning Project of Guangdong Province, Grant/Award Number: 2014A020212025 Abstract Lung hypoplasia is the main cause of congenital diaphragmatic hernia (CDH)‐ associated death but pathogenesis remains unclear. MiR‐455‐5p is involved in lung hypoplasia. We hypothesized that nitrofen causes abnormal miR‐455‐5p expression during lung development and designed this study to determine the relationship between miR‐455‐5p, stimulated by retinoic acid 6 (STRA6), and retinol in a nitrofen‐ induced CDH with lung hypoplasia rat model. Nitrofen or olive oil was administered to Sprague‐Dawley rats by gavage on day 9.5 of gestation, and the rats were divided into a nitrofen group and a control group (n = 6). The left lung of fetuses was dissected on day 15.5. The expression of miR‐455‐5p or STRA6 messenger RNA (mRNA) was determined by quantitative real‐time polymerase chain reaction. Average integrated optical density (IOD) of STRA6 protein was determined by immunofluorescence histochemistry. The average retinol level was detected by enzyme‐linked immunosorbent assay (n = 6 lungs, respectively). Compared with the control group, the nitrofen group exhibited significantly increased miR‐455‐5p expression levels (29.450 ± 9.253 vs 5.955 ± 2.330; P = .00045) and significantly decreased STRA6 mRNA levels (0.197 ± 0.097 vs 0.588 ± 0.184; P = .0047). In addition, the average IOD of the STRA6 protein was significantly lower in the nitrofen group (805.643 ± 291.182 vs 1616.391 ± 572.308, P = .015), and the average retinol level was significantly reduced (4.013 ± 0.195 vs 5.317 ± 0.337 μg/L, P = .000). In summary, the overexpression of miR‐455‐5p affected retinol absorption by downregulating STRA6 in the nitrofen‐induced CDH with lung hypoplasia rat model, and this downregulation may be one cause of CDH with lung hypoplasia.
Older adults show elevated intermuscular coherence in eyes‐open standing but only young adults increase coherence in response to closing the eyes

What is the central question of this study? Can a 14‐week strength‐training programme modify intermuscular coherence levels during bipedal standing tasks with eyes open and eyes closed and reduce age‐related differences? What is the main finding and its importance? Older adults had more prominent common input over 4–14 Hz with eyes open, but during the eyes‐closed task the young adults were able to further enhance their common input at 6–36 Hz. This indicates that young adults are better at modulating common input in different motor tasks.
Rato como modelo animal para avaliação da toxicidade induzida pela exposição crônica a efluentes de curtumes : parâmetros comportamentais e bioquímicos

Industrial development is one of the biggest responsible of water contamination. The tanning industry is one of the major polluters, and its effluents have high concentrations of toxic chemicals such as chromium salts and sulfides. The photoelectrochemical treatment is an alternative for the treatment of effluent as the goal to reduce their toxicity. Exposure to pollutants may be associated with increased risk of developing degenerative diseases as Alzheimer's and Parkinson's. Ecotoxicological studies using mammals as experimental animals are rare, so the effluent toxicity data in this class are scarce. This work aimed to study neurotoxicity and hepatotoxicity induced by chronic exposure to tannery effluent. Male Wistar rats were subjected to chronic treatment of tannery effluents (30 or 45 days) with or without photoelectrochemical treatment, added to drinking water. During the exposure, tests were performed on behavioral models of anxiety (elevated plus-maze, neophobia, open field and light-dark box), depression (forced swimming) and memory (inhibitory avoidance, novel object and discriminative avoidance). After this period the brain structures hippocampus, cerebellum and striatum were used to assess oxidative damage in the tests: determination of free radical content (DCF), a measure of lipid peroxidation (TBARS) and activity of the enzyme superoxide dismutase (SOD). The activity of the enzyme acetylcholinesterase (AChE) was assessed in brain structures hippocampus and striatum. Hepatotoxicity was assessed by the cellular oxidative state in the liver through the tests DCF, TBARS and the enzime catalase activity (CAT) and serum markers of liver damage: albumin, alkaline phosphatase, alanine aminotransferase (ALT) and aspartate aminotransferase (AST). Our results show that chronic exposure to tannery effluent with or without photoelectrochemical treatment on rats, showed no changes in tests of neurotoxicity and hepatotoxicity. This suggests that rats are not good models for ecotoxicological studies with tannery effluents. Similar studies are needed to determine the susceptibility of different species to contaminants.