Miracle-dz/UniFAR-FTUs huggingface dataset:
Association between TP53 and MDM2 Gene Polymorphisms and Risk of Hepatocellular Carcinoma in Hepatitis C Virus among Egyptian Populations

Background: The Murine double minute 2 (MDM2) gene is overexpressed in several human tumors. The oncogenic potential of MDM2 is partially explained by inhibition of the activity of the tumor suppressor protein P53 (negative regulator of the P53 tumor suppressor protein). A single nucleotide polymorphism (SNP) in the promoter region of MDM2 gene (T to G exchange at nucleotide 309) and TP53 gene (codon 72 exon 4, rs1042522 encoding either C or G) have been independently associated with increased risk of several cancer types. Few studies have analyzed the role of these polymorphisms in the development of hepatocellular carcinoma among Egyptian patients with chronic hepatitis C virus infection. Original Research Article Zaky et al.; AJRB, 7(4): 148-156, 2020; Article no.AJRB. 63819 149 Methods: The study consisted in the comparison of the genotype distribution of TP53 and MDM2 SNP309 in 100 viral hepatitis C-related hepatocellular carcinomas (HCC) cases and 100 controls without HCC matched for age, gender and ethnicity. PCR-RFLP (restriction fragment length polymorphism) and real time PCR methods were used to determine the genotype at the MDM2 SNP309T>G locus and TP53 rs1042522. Results: Overall, our results indicate that frequencies of TP53 alleles (C and G) were not significant different between HCC cases and healthy controls (p=0.093) (Odds Ratio, OR=1.361,95% Confidence Interval, 95% CI=0.949 – 1.951). A significant increase of MDM2 SNP309 G/G and T/G genotypes were observed among HCC cases (Odds Ratio, OR=4.868, 95% Confidence Interval, 95% CI= 2.873 – 8.251). Conclusions: Our finding suggest that people who have G allele increase the risk by 4.868 folds for developing HCC among Egyptian patients, consequently the MDM2 309T>G polymorphism is an important modulator of hepatocellular carcinoma development in Egyptian patients.
Formulation processes of monolingual, bilingual, and biliterate writers: Effects of biliteracy

By looking beyond their written products into what they do as they write, this mixed methods study offers insights into the writing process of writers who have mastered one language and those who have mastered two. It investigates the cognitive effects of bilingualism and biliteracy on the writing processes of years ten and eleven Sydney high school writers across three groups (N = 30): English monolinguals, Chinese-English bilinguals, and Chinese-English biliterates, focusing on their formulation processes (i.e., how thoughts are converted into language and the written form). Findings indicate distinctive features and patterns of writing behaviours, possibly reflecting specific strengths and weaknesses for each group. The monolinguals demonstrated strategic use of vocabulary, while the biliterates and bilinguals demonstrated prospective and retrospective behaviours when formulating. These findings are discussed in light of studies on the writing process and on the effects of bilingualism.
Physical Activity After Delivery: A Feasibility Study

Background: Early mobility is one of the main goals of the enhanced recovery after cesarean delivery, yet it is rarely objectively measured. Benefits related to this goal include mechanical prevention of deep venous thrombosis and early discharge. Methods: We conducted a multi-center prospective study in which an activity tracker was utilized to measure the steps taken by patients after delivery. The primary outcome was steps taken after vaginal or cesarean delivery. Secondary outcomes was factors affecting ambulation (e.g pain/satisfaction with pain management and mode of delivery). Results: Data from 50 postpartum patients were analyzed. Vaginal delivery patients took more cumulative steps at all times when compared to cesarean delivery patients. At 24 and 48 h vaginal and cesarean delivery patients took 5911 ± 2162 versus 3421± 2314 (P = 0.0006) and 9813 ± 3916 versus 6306 ± 5835 (P = 0.03), respectively. In the random effects mixed model, mode of delivery and time main effect were also significant (p<0.0001). In addition, each point increase in body mass index was noted to decrease the number of steps by 35 (95% CI -68 to -3). Conclusion: Ambulation in the first 48 h after delivery is mainly affected by the mode of delivery and body mass index.
Evaluation of Antioxidant Activity of Curcumin-Free Turmeric (Curcuma longa L.) Oil and Identification of Its Antioxidant Constituents

Antioxidant capacity of curcumin-free turmeric (Curcuma longa L.) oil was evaluated by two different in vitro assays: the DPPH radical scavenging assay and reducing power assay. Results showed that the turmeric oil (TO) possessed strong free radical scavenging activity and reducing power when compared to standard antioxidants such as butylated hydroxytoluene (BHT) and α-tocopherol (VitE). An aliquot of 20 μL/mL TO showed 91% free radical scavenging activity in the DPPH* assay, which was comparable to 10 mM BHT (86%) and 10 mM VitE (96%) under the same conditions. In the reducing power assay, the absorbance at 700 nm of 20 μl/mL TO was 1.085, which was comparable to 10 mM BHT (1.164). Higher concentration of TO at 100 μL/mL reached an absorbance of 1.537, which had no significant difference with 10 mM VitE (1.530). Among the complex constituents in the crude TO, ar-turmerone, turmerone, curlone and α-terpineol that were found to be the major components responsible for the detected antioxidant activities were isolated and identified using various chromatographic techniques including silica gel open column chromatography, normal phase HPLC, and GC-MS. These results showed that TO and some of its inherent bioactive components could potentially serve as alternative natural antioxidants.
Study of 100 Cases of Infertility with Polycystic Ovarian Syndrome at a Tertiary Hospital

This study "study of 100 cases of infertility with pcod" was carried in department of OBG at skims soura. Aims & Objectives: To study the impact of pcod in infertility and different treatment modalities Inclusion Criteria: All cases of primary and secondary infertility Exclusion Criteria: All other causes of infertility. Hyperprolactinemia, male factor infertility, hypothroidism Results: Most common age group of infertile pcod was 25 years. Primary infertility was seen in 80%. Duration of infertility was <3 years. pcod was more with BMI >26. In our usg was used as main dx criteria. Treatment was started as life style modification, followed by treatment with ovulation induction drugs with and without metformin, and laproscopic ovarian drilling. Introduction Infertility is the apparent failure of a couple to conceive after one Year of unprotected intercourse because of one or other reason. Among the ovulatory factors the most important cause is pcod. , that Leads to an ovulatory infertility (1, 2,3) . The prevelance of pcod is 5-10%in women of child bearing age. (4,5) . Clinical features of patients affected by pcod include infertility, both Primary and secondary, menstrual irregularities, hirsutism, acne because of Hyperandrogenism (6,7) . This needs to exclude other causes of hyperandrogenism Such as congenital adrenal hyperplasia, androgen secreating tumours Hyperprolatinemia. Pcos is also known as Stein leventhal syndrome and Is actually a multi system disorder affecting skin, hair and reproductive System (8) . In year 2003 Rotterdam held a conference that was Sponsored by ESHRE (European society of human reproduction And Embryology) and ASRM (American Society for reproduction Medicine) In this conference diagnostic criteria of pcod Was established on the basis of at least two of the three Criteria; 1) Oilgo-ovulation/anovulation 2) Clinical and biochemical signs of hyperandrogenism 3) Polycystic ovaries on usg. Pathology of pcod has genetic component and is transmitted as autosomal dominant trait. Besides genetic other factors Are implicated in occurrence of pcod including dietary factors, Environmental and still http://jmscr.igmpublication. org/home/ ISSN (e)-2347-176x ISSN (p) 2455-0450 DOI: https://dx.doi. org/10.18535/jmscr/v8i12.40
Chromosome Level Genome Assembly Reveals Cassia Tora May Be an Ancient Species in Leguminosae

Background: Cassia tora L. is an annual leguminous plant. Its seeds had wide utility in herbal medicine in Asian, but is usually regard as a potent, invasive weed which even helps farmers eliminate other parasitic weed species. However, compared with other important legume crops, C. tora is far from fully developed and the genetic basis is greatly lacking. A reference genome sequence will be great valuable resource for its genome evolution, genetic breeding and development.Results: Here, we de novo assembled a chromosome-scale genome for C. tora by combining PacBio sequencing technology with chromatin interaction mapping, resulting in 621-Mb genome with a contig N50 of 2.5 Mb, of which 77.44% was ordered and oriented on 13 pseudochromosomes. The genome contained 32,361 protein-coding genes with a repetitive DNA content of approximately 58.15%. Gypsy-type LTRs constituted the largest subfamily. LTR insertion events seldom occurred in this genome over the past 10 million years. Comparative genomic analyses showed that C. tora diverged ~95 million years ago (MYA), which revealed it has the most distant genetic relationship with 11 other legumes. Compared with other legume crops, Cassia tora is maybe an ancient species in Leguminosae.Conclusions: The high-quality reference genome sequence reported here furnishes unprecedented insights into genome dynamics and provides an important basis for future research on legume genome evolution.
Emotional Labor of Frontline Employees: Generational Differences and Intention to Stay

ABSTRACT Emotional labor often takes the form of displaying fake or genuine feelings toward customers, showing interest in customer needs, and engaging in employee-customer emotional interactions. The purpose of this research was to investigate the emotional labor states adopted and practiced by frontline employees in the hospitality industry. We analyzed significant differences of emotional labor among Generation X and Y, and socio-demographic characteristics of frontline employees. The influence of emotional labor states on frontline employees’ intention to stay is also examined. The emotional labor states applied here were surface acting, deep acting, genuine acting and emotive dissoance. A quantitative approach was adopted and data were collected from three-, four-, and five-star hotels in Hong Kong. The study found that Generation X respondents adopted genuine acting and emotional dissonance more often, while Generation Y respondents used surface acting and deep acting more frequently. The findings suggest that although surface acting has a significant effect on employees’ intention to stay, genuine acting and sincere feelings toward one’s job have a stronger effect.
Economic and Social Implications and Challenges of Relocation of Street Vendors in a Highly Urbanized City

On July 29, 2019, the Department of the Interior and Local Government (DILG) issued Memorandum Circular 2019-121 (DILG MC 2019-121), ordering the local chief executives to clear roads, sidewalks, and rights-of-way of obstructions. The descriptive-comparative research design was used to describe the economic and social implications of their relocation. A validated and reliability-tested survey questionnaire was used to gather data from 197 displaced vendors peddling in the downtown of a highly urbanized city. The findings of the study showed that the relocation of the displaced vendors did not change their economic conditions in terms of their average monthly sales, expenses, and income, but significantly differ when grouped and compared according to their age, educational attainment, family size, years of vending, and types of merchandise. Likewise, their social well-being did not change in terms of education and health and significantly differ when grouped and compared according to the aforementioned variables. Moreover, the major challenges faced by the relocated vendors were as follows: their means of livelihood is very difficult; not enough financial support is given during their relocation; limited space/trading site; and lack of access to the credit facility. The local government may utilize the study to implement a transit-oriented development of these vendors.
Preparation and adsorption property of solanesol molecular imprinted polymers

Molecular imprinted polymers of solanesol (SSO-MIPs) were synthesized through solution polymerization using solanesol (SSO) as the template molecule, N-vinylpyrrolidone (NVP) and acrylic acid (AA) as functional monomers, ethyleneglycol dimethacrylate （EGDMA) as cross-linker and azodiisobutyronitrile (AIBN) as initiator. Focused on the adsorption capacity and separation degree of MIP-SSO to SSO from the mixture of SSO and Triacontanol (TAL), the effects of the monomers, cross-linker and initiators on them were investigated and optimized. Finally, the structure of MIP-SSO prepared under the optimal conditions was characterized using Fourier transform infrared and scanning electron microscope. To obtain the more objective results, non-imprinted molecular polymers (NMIPs) prepared under the same condition was also characterized as contrast.
CSR, Co-Creation and Green Consumer Loyalty: Are Green Banking Initiatives Important? A Moderated Mediation Approach from an Emerging Economy

The homogenization of the banking segment has made it difficult for banking institutions to practice the quality of services that are needed in order to retain consumers. Thus, these days, finding ways to increase consumer loyalty—especially green loyalty—has become a challenge for the banking industry around the planet. Research has long acknowledged that corporate social responsibility (CSR) is a strategic concern that could help organizations to increase consumer loyalty. However, the impact of CSR practices on green consumer loyalty is rarely addressed in the extant literature. Hence, the present research investigated the impact of CSR on green consumer loyalty with the mediating effect of co-creation in the banking industry of Pakistan. The study also introduced green banking initiatives as a moderator between the mediated relation of CSR and green consumer loyalty, with the intention that such a moderator would strengthen this indirect relationship. The structural equation modeling technique was used for the data analysis. The results confirm that CSR enhances consumer loyalty, and that co-creation partially mediates this relationship. Furthermore, green banking initiatives further strengthen this relation. The results of the current survey could help banking institutions learn how they can develop core strategic considerations based on the integration of CSR co-creation and green banking initiatives.
The Lie as An Indicator of Social Maladjustment of Young People

The aim of the study was to compare views and attitudes towards lies held by Polish teenagers who were properly socialized and socially maladjusted (179 people). The diagnostic survey method and the questionnaire technique were used. It has been established that socially adapted youth better recognize lies, more often use altruistic and manipulative lies, more often lies to parents and teachers. Also, being lied to more often, they react with breaking contact with the liar and experience disappointment and anger; moreover, in the situation of being caught lying, they experience shame more often. In turn, socially maladjusted young people use destructive lies that aim to hurt someone. It was also found that the use of a lie, views on the admissibility of a lie and the tendency to justify it are independent of social adaptation.
Serum zinc status in thalassemic adolescents attending Yangon Children Hospital, Myanmar

Background: Thalassemia constitutes a major public health problem causing a significant burden on children and their families. Zinc deficiency plays an important role in many thalassemia-related complications like growth retardation, hypogonadism and delayed puberty which are frequently noted in adolescent age. Although zinc is supplemented to thalassemic patients visiting Day Care Center, Yangon Children Hospital (YCH), Myanmar, a report concerning serum zinc level of these patients is still lacking. This study, therefore, aimed to assess serum zinc status in thalassemic adolescents attending Day Care Center, YCH. Materials and Methods: This hospital-based cross-sectional study was conducted on 99 thalassemic adolescents. Mean age of diagnosis was 5.1±2.1 years. Non-fasting serum zinc concentration was determined by atomic absorption spectrophotometry. According to National Health and Nutrition Examination Survey data, zinc deficiency was defined as serum zinc concentration < 66 μg/dL (female) and < 70 μg/dL (male). Results: Serum zinc concentration (μg/dL) was 57.35 (47.30-80.14) (median, interquartile range) with maximum, 195.05 and minimum, 28.83. Zinc deficiency was observed in 69.7% (69 out of 99; 35 males and 34 females) of the patients. The associations of zinc deficiency with gender, phenotype and the use of chelator were nonsignificant (P>0.05). Conclusion: In spite of zinc supplementation, nearly 70% of the thalassemic adolescents showed zinc deficiency. Zinc deficiency in these adolescents might not be related to gender, phenotypes or the use of chelator. Poor compliance to take zinc supplementation and/or irregular blood transfusion could partly be attributable to zinc deficiency in these adolescents. Providing health education on the importance of regular intake of adequate zinc is advisable and periodic evaluation of zinc levels is recommended for thalassemic adolescents.
Face Gender Recognition in the Wild: An Extensive Performance Comparison of Deep-Learned, Hand-Crafted, and Fused Features with Deep and Traditional Models

Face gender recognition has many useful applications in human–robot interactions as it can improve the overall user experience. Support vector machines (SVM) and convolutional neural networks (CNNs) have been used successfully in this domain. Researchers have shown an increased interest in comparing and combining different feature extraction paradigms, including deep-learned features, hand-crafted features, and the fusion of both features. Related research in face gender recognition has been mostly restricted to limited comparisons of the deep-learned and fused features with the CNN model or only deep-learned features with the CNN and SVM models. In this work, we perform a comprehensive comparative study to analyze the classification performance of two widely used learning models (i.e., CNN and SVM), when they are combined with seven features that include hand-crafted, deep-learned, and fused features. The experiments were performed using two challenging unconstrained datasets, namely, Adience and Labeled Faces in the Wild. Further, we used T-tests to assess the statistical significance of the differences in performances with respect to the accuracy, f-score, and area under the curve. Our results proved that SVMs showed best performance with fused features, whereas CNN showed the best performance with deep-learned features. CNN outperformed SVM significantly at p < 0.05.
Effect of Topical Application of Human Breast Milk, Chlorhexidine and Dry Cord Care on Neonatal Umbilical Cord Separation Time and Rate of Cord Infection : Cluster Randomized Trial

Background- Annually 1 million newborns worldwide die of infection caused by bacteria that enter the body via the umbilical cord. Regarding this the Ethiopia national strategy of new born and child survival identified Chlorhexidine as one of the high impact interventions to minimize neonatal mortality. Whereas, studies have shown Human breast milk application to the neonatal umbilical cord has a shorter cord separation time and lower rate of infection than Chlorhexidine or dry cord care. Method- From May to November, 2018, a three arm, non- masked, community based, cluster randomized controlled trial was conducted at Butajira Demographic and Health Surveillance site located in the Gurage Zone of the Southern Nations, Nationalities and Peoples´ Region of Ethiopia. Nine sub districts of the Butajira Demographic and Health Surveillance site were randomized into two intervention groups that are human breast milk and Chlorhexidine and a control group which is the dry cord care using a lottery method. From a sample size of 337, data were entered and analyzed for 302 term singleton newborns. Baseline characteristics across the groups were compared by ANOVA for continuous variables and Chi square for categorical variables. Mean cord separation time was compared among the groups using one way ANOVA whereas the secondary outcome i.e. rate of omphalitis was expressed in terms of frequency and was compared among the groups using Chi square. Level of significance was set at p <0.05 with 95% confidence interval. Result- The mean cord separation time was 5.6 days in the human breast milk group, 5.9days in the Chlorhexidine group, and 5.7days in the dry cord care group but this difference was not statistically significant among the study groups (p value=0.40). The highest signs of cord infection rate were observed in the dry care group and this was significant regarding the redness on the base of the cord stump (P<0.001). Conclusion- Topical application of human breast milk is related with shorter cord separation time compared to chlorhexidine or dry cord care. It also has reduced incidence of infection, as much as topical chlorhexidine application. Generally the readily available human breast milk should be given further emphasis.Trial registration- This trial is registered at the Pan African Clinical Trial Registry on 27th August 2020 with a clinical trial registration number of PACTR202008804462886 . It can be accessed using the URL address:https://pactr.samrc. ac.za/TrialDisplay.aspx? TrialID=593.
Self-Image Improvement and Iranian EFL Learners’ Oral Performance: Effects on Complexity, Accuracy, and Fluency

The present study intended to investigate the effects of self-image improvement on quality of Iranian EFL learners’ oral productions. To this aim, 30 lower-intermediate university students were randomly divided into an experimental (EG) and control (CG) groups. The main focus in both groups was enhancing the students’ oral performance while only the EG received the treatment via self-image improving techniques. Their self-image was measured with the aid of Offer Self-Image Questionnaire and their oral performance was examined using two parallel IELTS speaking tests before and after the treatment. It was found that by receiving self-image training, participants’ self-image improved, which led to a parallel improvement in their speaking skill. More specifically, the EG improved significantly in oral complexity and two components of oral fluency, MLR and speech rate A. However, regarding oral accuracy and speech rate B, no significant difference was observed between the two groups.