Miracle-dz/UniFAR-FTUs huggingface dataset:
Assessment of Musculoskeletal Pain among Patients with Vitamin D Deficiency

Background: Hypovitaminosis D is a worldwide health problem. There have been very few studies establishing the relationship between Vitamin D deficiency and muscular pain, and the effect of managing them with substitution with Vitamin D. The present study was conducted to assess vitamin D levels amongst subjects with musculokeletal pain. Materials and methods: The present prospective descriptive study was initiated in the General Medicine department, D.B. Hospital, Churu, Rajasthan, India during a period of 1 year. Calorimetry was used for assessment of calcium levels. ELISA reader awareness was used to determine the levels of vitamin D. All the subjects having deficiency of vitamin D were managed with 50000 unit per week of vitamin D3 and 1000mg per day of calcium. They were followed up for a period of 4 months and assessment of pain was done. Student T-test and Mann whitney were used for the analysis of data. Probability value of less than 0.05 was considered significant. Results: The mean age of the study subjects was 35.6 ±10.4. The mean calcium level was 9.5 ± 0.5 mg/dl. The mean parathyroid level was 46.2 ± 40.1 Pmol/L. The mean Vitamin D level was 21.6 ± 10.2 nmol/l. There were 78.3% responders and 60% nonresponders with Vitamin D level more than 25nmol/L. The mean Vitamin D level after treatment amongst the responders and non-responders was 61.6±28.6 and 38.2±9.5 respectively. Conclusion: In our study also significant difference in the level of Vitamin D was seen amongst the responders and the non responders.
Simultaneous pars plana vitrectomy, panretinal photocoagulation, cryotherapy, and Ahmed valve implantation for neovascular glaucoma.

AIM To describe and evaluate the efficacy of Ahmed glaucoma valve implantation (AGV) combined with pars plana vitrectomy (PPV) in a single surgical act for the treatment of advanced neovascular glaucoma (NVG). METHODS Retrospective observational case series included 51 eyes from 50 patients with severe NVG treated with PPV, AGV, and panretinal photocoagulation and/or cryotherapy in a single surgical act during a 13-year period (2005-2018). Preoperative, intraoperative and postoperative data at day 1 and months 1, 3, 6, 21, and 24 were systematically collected. Definition of surgical success was stablished at IOP between 6 and 21 mm Hg with or without topical treatment. RESULTS Main indications for surgery were NVG secondary to proliferative diabetic retinopathy (39.2%) and central retinal vein occlusion (37.3%). Mean (±SD) preoperative IOP was 42.0±11.2 mm Hg decreasing to 15.5±7.1 mm Hg at 12mo and 15.8±9.1 mm Hg at 24mo of follow up. Cumulative incidence of success of IOP control was 76.0% at first postoperative month, reaching 88.3% at 6mo. Prevalence of successful IOP control at long term was 74.4% at 12mo and 71.4% at 24mo. Eye evisceration for unsuccessful NVG management was required in 1 case (2.0%). CONCLUSION Combination of AGV implantation and PPV in a single act may be a suitable option for severe forms of NVG in a case-by-case basis for effective IOP control and a complete panretinal photocoagulation.
Simulation Experiment to Predict the Critical Friction Area of Acetabular Liner Component on Hip Joint Replacement Implant During Movement

This paper has shown that simulation experiment to predict the critical friction area of acetabular liner component on hip joint replacement implant during movement. With the simulation method, that can help find the friction and stress area. The results of the friction simulation, the area friction of acetabular liner is 378,32 mm2 and 22,49 mm2 for the femoral head. Based on simulation stress analysis of acetabular liner shown the maximum value of von-Mises stress is 0.3994 MPa and for the femoral head is 0.3411 MPa. From the simulation results, a map of the critical contact area is obtained, which is an important reference in the development of optimal designs for the acetabular liner and femoral head components.
Effects of the prebiotic lactoferrin on multidrug-resistant Escherichia coli infections in broiler chickens

Abstract Background and Aim: Increased multidrug resistance in Escherichia coli has created challenges for the poultry industry. Consequently, new antimicrobial agents should preferentially be utilized for the prevention and treatment of E. coli outbreaks. This study aimed to evaluate the effects of lactoferrin (LF) as a prebiotic on broiler chicks challenged with multidrug-resistant E. coli in comparison with antibiotics. Materials and Methods: A total of 70 diseased flocks from Egypt were collected for E. coli isolation and identification, serotyping, and antimicrobial susceptibility pattern determination. E. coli was isolated and characterized phenotypically and one isolate that showed multidrug-resistance was selected. A challenge trial was performed to evaluate the effectiveness of LF as a prebiotic on the isolated multidrug-resistant E. coli. Liver samples were collected from the experimental chicks and subjected to E. coli enumeration to illustrate the effectiveness of LF on the liver cells and bacteria using an electron microscope. Serum samples were also collected to estimate lysozyme and nitric oxide (NO) concentrations. Results: After isolation of E. coli with a percentage of 54.3% from the diseased broilers, the strain was serotyped (identified serotypes: O2, O18, O55, O78, O86a, O111, O125, O126, O127, O157, O159, and O166). Multi-antibiotic resistance was found to be harbored in a high percentage among 11 antibiotic discs. The LF in the prophylactic and treated groups was found to have a significant effect in comparison with the group treated with the drug of choice (ciprofloxacin). Furthermore, a significant difference in the NO (one of non-specific immune response) and a non-significant difference in lysozyme concentrations were reported in the group fed on rations with LF in comparison with the non-fed group. Conclusion: LF was thus identified as an effective prebiotic that can improve chick performance, help them to overcome multidrug-resistant E. coli and stimulate immunity.
Human Vehicle Dynamics Coupling of Miniature Electric Vehicle Roll Stability: Effects of Driver Weight, Wheel Base and Track Width

As a continuation of the previous research, influences of human vehicle dynamics coupling (HVDC) on miniature electric vehicle (MEV) roll stability are studied by varying driver weight, wheel base and track width. A multi-body dynamics model is developed for the human-vehicle system by ADAMS/Car software considering driver’s dynamics and is validated theoretically. Simulation results show that the MEV roll stability is decreased by the HVDC; the influences become greater with an increase in the proportion of the driver weight to curb weight of the MEV in both time and frequency domain; with the decrease of wheel base, the differences caused by the HVDC exhibit an increasing trend in the maximum value and overshoot; and the differences in the steady stable roll angle and phase lag at 0.6 Hz indicate an increasing tendency with the decrease of track width.
Plasmonic coupling in graphene nanoribbon dimers

Plasmonics in graphene nanostructures has shown great promise for terahertz and mid-infrared applications. In order to achieve multiple functionalities and broad operating bandwidth, the nanostructures are usually very compact, in which plasmonic coupling is inevitable and even plays an important role in performance improvement. Here, we investigate plasmonic coupling in graphene nanoribbon (GNR) dimers theoretically through full wave simulation and coupled dipole approximation. In practice, we treat GNR dimers as a pair of Lorentz type point dipoles, whose coupling is described by a phenomenological parameter (coupling strength). We show the resonance line-shape of GNR dimers can be engineered by tuning the distance, resonance frequency difference, damping rates of two GNRs. However, in both horizontally aligned dimer (HD) and vertically aligned dimer (VD), the coupling strength only depends on the distance, and exhibits an inverse relation of cube root, but due to different symmetries, they are opposite in sign. When two GNRs are placed with an increasing oblique angle, the coupling strength varies continuously from the value of HD to that of VD, and satisfies a sinusoidal function of the angle. We further discuss a general scheme to engineer broadband optical response through tuning damping rates of two GNRs, namely, larger damping rate for lower frequency resonance in HD, while on the contrary in VD. Our results provide a basic understanding of plasmonic coupling in graphene nanostructures, and will stimulate graphene plasmonic applications at terahertz and mid-infrared frequency range.
ASSOCIATION OF TRAUMA FROM OCCLUSION AND GINGIVAL RECESSION IN MANDIBULAR ANTERIOR TEETH

1 Saveetha Dental College & Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai -77 2 Senior Lecturer, Department of Periodontics, Saveetha Dental College & Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai-77 3 Associate professor, Department of Oral and Maxillofacial Surgery, Saveetha Dental college & Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai-77. 1 151701041.sdc@saveetha.com 2 arvinar.sdc@saveetha.com 3 senthilmuruganp.sdc@saveetha.com ABSTRACT:
AUDIT COMMITTEE, CAPITAL STRUCTURE AND LIQUIDITY: INTERACTION AND IMPACT ON EARNINGS QUALITY

The purpose of this research is to determine the effect of capital structure and liquidity on earnings quality with the audit committee as a moderating variable. The research population was manufacturing companies listed on the Indonesia Stock Exchange (BEI) for the period 2017-2019 totaling of 144 companies. The sampling method used was purposive sampling and obtained 40 companies as a sample. The data analysis used was mulpiple regression and run under SPSS rogram. The result shows that capital structure, liquidity, and committee audit silmutaneusly affect earnings quality. Partially, capital structure has negative significance effect on earnings quality, and liquidity has no significant effect on earnings quality. Meanwhile committee audit able to strengthen the effect of capital structure on earnings quality, and committee audit do not able to strengthen the effect of liquidity on earnings quality.
Electrochemical Properties of Nb-Substituted Zr-Ti-Ni Hydrogen Storage Alloy Negative Electrodes for Nickel-Metal Hydride Batteries

: Crystal structure, pressure-composition isotherms and electrochemical properties of the Zr 0.6 − x Ti 0.4 Nb x Ni ( x = 0.01, 0.02, and 0.05) alloys were investigated. Their X-ray diffraction proﬁles demonstrated that all the Zr 0.6 − x Ti 0.4 Nb x Ni alloys consisted of the primary phase with the B33 -type orthorhombic structure and the secondary phase with the B2 -type Ti 0.6 Zr 0.4 Ni cubic structure. Rietveld reﬁnement demonstrated that the atomic fraction of the secondary phase increased with the Nb content. The Zr 0.6 − x Ti 0.4 Nb x Ni alloys were lower in hydrogen storage capacity than the Nb-free Zr 0.6 Ti 0.4 Ni alloy due to an increase in the abundance of the secondary phase. In the charge-discharge tests with the Zr 0.6 − x Ti 0.4 Nb x Ni alloy negative electrodes, all the initial discharge curves had two potential plateaus due to the electrochemical hydrogen desorption of trihydride to monohydride and monohydride to alloy of the primary phase. The total discharge capacities at 333 and 303 K for the Zr 0.58 Ti 0.4 Nb 0.02 Ni alloy negative electrode were 384 and 335 mAh g − 1 , respectively, which were higher than those of the other Zr 0.6 − x Ti 0.4 Nb x Ni and Zr 0.6 Ti 0.4 Ni alloy negative electrodes.
Neuropsychiatric Manifestations of Wilson Disease in Sudan

Background: Delineating the neuropsychiatric pattern and features of Wilson disease is essential step to better recognition and management of these presentations. To our knowledge this is the first large study of neuropsychiatric manifestations of Wilson disease in Sudan. Method: A comprehensive case finding survey was conducted over a six month period, in the Capital of Sudan, covering all secondary and tertiary services that cater for patients with Wilson disease. Patients’ assessment was carried out using batteries of functional tests, including, ICD-10 research criteria for major psychiatric categories, Mini Mental State Examination, ADHD scale, school records, parental reports. All neurological findings were conducted and verified by two neurologists. Results: Fifty cases of Wilson disease, of varying age and stage of illness, were thoroughly examined for neuropsychiatric symptoms and disorders. Most patients 29 (58%) showed psychological disturbance in form of psychiatric illness and significant behavioural disturbance. Mood and emotional disorders observed in 21 (42%) of cases, core symptoms of depressive disorder diagnosed in 19 cases (38%), behavioural and personality disturbances detected in 19 patients (38%), while cognitive impairments were found in 24 (48%) of all cases. Twenty-one cases (42%) presented with neurological abnormalities, predominantly consisting of posturing in 20 (40%), dystonia in 8 (16%), Parkinsonism was found in 10 (20%) patients, dysarthria in 9 (18%), athetosis in 3 (6%) cases and various forms of tremors in 21 (42%). Epilepsy was recorded in 3 cases (6%). Conclusion: Neuropsychiatric symptoms and disorders are highly prevalent in Wilson disease patients regardless of age, or stage of illness. Even though, patients in our sample had had an average of 6 years follow up duration, non-had shown evidence of liver failure. This shows an early indication of possibly benign trajectory course of the illness in Sudan.
Inverse Halftone Colorization: Making Halftone Prints Color Photos

We propose to address the Inverse Halftone Colorization task, which tries to recover colorful images from black and white halftone prints, and can be treated as the joint problem of inverse halftone and colorization. Although the inverse halftone colorization seems to be achievable via applying inverse halftone followed by colorization, our proposed method advances from two perspectives: (1) we empirically discover that the orders of cascading inverse halftone and colorization (i.e first inverse halftone then colorization versus the reverse order) would lead to results with different properties, hence a fusion scheme is proposed to integrate their results; (2) we introduce several novel losses to encourage the realness, diversity, and the structural coherence of the colorization. Moreover, our model is flexible to support both exemplar-based and random colorization. We conduct extensive experiments to demonstrate the efficacy of our method as well as verify the contributions of our design choices.
Evaluation of the bactericidal effect of some disinfectants against E.coli and Salmonella isolated from poultry hatcheries

Poultry production considers one of the most important activities for economy and income in many countries . Proper management and hygiene in poultry hatchery mostly depend on efficient cleaning and sanitation of the hatchery environment and hatching eggs for production high quality newly hatched chicks . The aim of our study is to evaluate the effectiveness of some disinfectants (Aquavinol® 5%, Presept® 2.5%, Poviment® and MM8 ®) at various concentrations 1% , 1.5% and 2% at different contact times 30, 60, 90 and 120 minutes against E.coli and Salmonella which were isolated from the poultry hatcheries at a titer of 3×106/cm2. Our results showed that Aquavinol® 5% was the highest powerful disinfectant against these pathogens, followed by Presept® 2.5% and then Poviment® ,while MM8® was the weakest disinfectant at the same conditions. Our study concluded that the prevention & control of infections depend on the disinfectant of choice that must be applied with sufficient concentration at proper exposure time to achieve the best powerful effect on microorganisms with low costs.
The Formation of Risk Preferences Through Small-Scale Events

Large, macroeconomic shocks in the past have been shown to influence economic decisions in the present. We study in an experiment with 743 subjects whether small-scale, seemingly negligible, events also affect the formation of risk preferences. In line with a reinforcement learning model, we find that subjects who won a random lottery took significantly more risk in a second lottery almost a year later. The same pattern emerges in another experiment with 136 subjects where the second lottery was played more than three years after the first lottery. So, small-scale, random, events affect the formation of risk preferences significantly.
Assessment of spectral indexes for estimating soil water content in the Brazilian Pantanal

The Pantanal is the largest floodplain of the globe occupying 138,183 km in Brazil. The fundamental ecological factor of interaction between the Pantanal ecosystems is the flooding regime. Connected to properties of the soil-plant-atmosphere system, knowledge on the soil water content becomes increasingly necessary. The high temporal and spatial variability of water content in the soil caused by the vast heterogeneity of soil texture, vegetation, topography and climate makes it a difficult physical variable to be measured. However, its spatial and temporal variability can be determined by recent modern techniques of remote sensing based on data obtained by microwave or infrared sensors. Thus, the aim of this study was to evaluate the accuracy of vegetation and soil water indexes through satellite images from Landsat 5 in the northern Brazilian Pantanal. The study was conducted in a pasture, experimental site in the Northern Pantanal in Mato Grosso state. Soil moisture was measured using a TDR probe installed at 10 cm depth in the period from 2009 to 2011. For comparison, spectral indexes and the surface temperature provided by Geological Survey (USGS) were used, these indexes are derived from bands ratios of satellite reflectance products Landsat 5 TM. The data evaluation was performed using some indicators: accuracy Willmott index, Root Mean Square Error and the Mean Absolute Error. This study demonstrated that the application of remote sensing in the management of water resources is very promising. The indexes correlated with soil moisture measurement. Among the soil water indexes the NBR-2 showed related to soil moisture measurement. For both types of soils EVI had the highest determination coefficient, lowest errors and highest Willmott’s index of agreement. Palavras-chave: Pasture; Remote sensing; Landsat 5 2 | Assessment of spectral indexes for estimating soil water content in the Brazilian Pantanal Ci. e Nat., Santa Maria, v.43, e48, 2021
High-Performance Deep learning to Detection and Tracking Tomato Plant Leaf Predict Disease and Expert Systems

97 Azhee Wria Muhamad, Yaser A. Jasim, Mostafa Ismael Shukri Windi, Mustafa Ghanem Saeed, Sadeeer Dhyaa AbdulAmeer High-Performance Deep learning to Detection and Tracking Tomato Plant Leaf Predict Disease. ADCAIJ: Advances in Distributed Computing and Artificial Intelligence Journal Regular Issue, Vol. 10 N. 2 (2021), 97-122 eISSN: 2255-2863 https://adcaij.usal. es Ediciones Universidad de Salamanca cc by-nc-nd High-Performance Deep learning to Detection and Tracking Tomato Plant Leaf Predict Disease and Expert Systems
Inhibition of miR-483-5p improves the proliferation, invasion and inflammatory response of triple-negative breast cancer cells by targeting SOCS3

microRNAs (miRs) have been indicated to serve oncogenic or tumor suppressor roles. However, the role of miR-483-5p in breast cancer and its associated molecular mechanisms remain unclear. In the present study, compared with adjacent normal tissues and MCF-10a cells, the expression level of miR-483-5p was upregulated in triple-negative breast cancer (TNBC) tissues and TNBC cell lines. Bioinformatic analysis and luciferase reporter assay confirmed the presence of miR-483-5p binding sites in the 3'-untranslated region of suppressor of cytokine signaling 3 (SOCS3). In addition, the expression level of SOCS3 protein in TNBC tissues was markedly lower compared with in adjacent tissues, and miR-483-5p expression was negatively correlated with SOCS3 expression in TNBC tissues. Cell proliferation and flow cytometry assays indicated that knockdown of miR-483-5p inhibited the proliferation and promoted apoptosis in the TNBC cell line BT-549. This effect was markedly attenuated by SOCS3 small interfering (si)RNA transfection. Additionally, wound healing and Transwell assays demonstrated that SOCS3 siRNA reversed the inhibitory effects of miR-483-5p inhibitor on the migration and invasion of BT-549 cells. Moreover, the decrease in miR-483-5p expression significantly reduced the secretion of TNF-α, IL-6, IL-1β and monocyte chemoattractant protein-1 in BT-549 cells, while SOCS3 siRNA could partially reverse this effect. Additionally, SOCS3 overexpression reversed the effects of miR-483-5p mimic on the proliferation, migration, invasion and inflammation of BT-549 cells. Taken together, these data demonstrated that the inhibition of miR-483-5p could inhibit the proliferation, migration, invasion and inflammatory response, while promoting the apoptosis of TNBC cells by negatively regulating SOCS3. miR-483-5p may be a potential target for TNBC therapy.
Long-term effect of α1-antitrypsin augmentation therapy on the decline of FEV1 in deficient patients: an analysis of the AIR database

Background Patients with ZZ (Glu342Lys) α-1-antitrypsin deficiency (ZZ-AATD) who received augmentation therapy with α-1-antitrypsin (AAT) in randomised controlled trials over 2–3 years failed to show a significant reduction of the annual decline of forced expiratory volume in 1 s (FEV1). Methods To compare the trajectory of FEV1 change during 4 or more years in ZZ-AATD patients with emphysema receiving or not receiving intravenous augmentation therapy, a retrospective analysis of FEV1 values entered in the Alpha-1 International Registry (AIR) of ZZ-AATD patients from five different European countries (Germany, UK, Spain, Italy and the Netherlands) was performed. The post-bronchodilator FEV1 % predicted values for baseline and follow-up over time from patients were analysed using linear mixed effects models. Results Data of 374 patients were analysed: 246 untreated and 128 treated with intravenous AAT augmentation therapy. The mean±sd follow-up duration of the untreated group was 8.60±3.34 years and 8.59±2.62 years for the treated group. The mixed effects model analysis showed a mean FEV1 decline of −0.931% predicted per year (95% CI −1.144 to −0.718) in the untreated group and a decline of −1.016% predicted per year (95% CI −1.319 to −0.7145) in the treated group. The likelihood ratio test showed no difference between the two groups (p=0.71). Conclusion In our study population, we could not detect a significant difference in the annual decline of FEV1 by AAT augmentation treatment over a mean period of 8.6 years. Other approaches are needed to validate any benefit of augmentation therapy. This analysis of European real-world follow-up data of FEV1 % predicted in ZZ α1-ATD patients showed no difference in annual FEV1 decline between the i.v. α1-AT augmentation treated and untreated patients over a period of >8 years https://bit.ly/35MglRc
Compliance with National Operational Guidelines for Community Management of Acute Malnutrition among Community Health Workers in Konduga Local Government Area of Borno State, Nigeria

Adewale M Adejugbagbe1*, IkeOluwapo O Ajayi1, Aderemi O Ayegbusi2, and Olubunmi P Oki3 1Department of Epidemiology and Medical Statistics, University of Ibadan, Nigeria 2Department of Animal Production and Health, Federal University of Technology Akure, Nigeria 3Department of Surgery, Federal Medical Center, Keffi, Nigeri