Miracle-dz/UniFAR-FTUs huggingface dataset:
Founding of the culture collection of antibiotic-resistant strains of zoonotic bacteria in the Russian Federation

Background and Aim: The main purpose of a national bioresource center is to standardize, centralize, preserve, and ensure accessibility of microbial bioresources that accumulate there because of state research programs. The establishment of national bioresource centers for antibiotic-resistant microorganisms allows to solve practical problems in the field of veterinary service, as well as to develop effective chemotherapeutic and disinfectant drugs to overcome the mechanisms of resistance. This study aimed to outline the process of forming a national culture collection of antibiotic-resistant strains of zoonotic bacteria in the Russian Federation using two microbial strains. Materials and Methods: The object of research was isolates of Salmonella spp. , Escherichia coli, Enterococcus spp. , Campylobacter spp. , Listeria monocytogenes, and Staphylococcus spp. , all of which were obtained from biomaterials of farm animals, feed samples, bedding, water from livestock buildings, washouts from environmental objects, and food products. The resistance of bacterial isolates was determined using microbiological and molecular-genetic research methods. Results: During monitoring studies, 1489 bacterial isolates were isolated. In total, 408 bacterial isolates were tested for sensitivity to antimicrobial agents, including E. coli (47.6%), Salmonella spp. (30.4%), Enterococcus spp. (11.3%), and Campylobacter spp. (10.8%). For genetic characterization, 95 isolates of Salmonella enterica, E. coli, Campylobacter spp. , L. monocytogenes, Staphylococcus spp. , Enterococcus spp. were chosen from the research collection, which was formed as part of the monitoring program for antibiotic resistance. Conclusion: Deposited isolates that underwent whole-genome analysis can be used as positive control samples both in the development and use of methods or test systems for the detection of various resistance genes in zoonotic bacteria. In addition, such isolates can also be used for microbiological studies related to determining the sensitivity of microorganisms to antibacterial drugs, for phenotypic studies in the diagnosis of various bacterial infections in animals and birds, and retrospective analysis of strains from numerous collections.
Validation of Gait Measurements on Short-Distance Walkways Using Azure Kinect DK in Patients Receiving Chronic Hemodialysis

Muscle dysfunction, skeletal muscle fibrosis, and disability are associated with weakness in patients with end-stage renal disease. The main purpose of this study was to validate the effectiveness of a proposed system for gait monitoring on short-distance 1.5 m walkways in a dialysis center. Gaits with reduced speed and stride length, long sit-to-stand time (SST), two forward angles, and two unbalanced gait regions are defined in the proposed Kinect v3 gait measurement and analysis system (K3S) and have been considered clinical features in end-stage renal disease (ESRD) associated with poor dialysis outcomes. The stride and pace calibrations of the Kinect v3 system are based on the Zeno Walkway. Its single rating intraclass correlation (ICC) for the stride is 0.990, and its single rating ICC for the pace is 0.920. The SST calibration of Kinect v3 is based on a pressure insole; its single rating ICC for the SST is 0.871. A total of 75 patients on chronic dialysis underwent gait measurement and analysis during walking and weighing actions. After dialysis, patients demonstrated a smaller stride (p < 0.001) and longer SST (p < 0.001). The results demonstrate that patients’ physical fitness was greatly reduced after dialysis. This study ensures patients’ adequate physical gait strength to cope with the dialysis-associated physical exhaustion risk by tracing gait outliers. As decreased stride and pace are associated with an increased risk of falls, further studies are warranted to evaluate the clinical benefits of monitoring gait with the proposed reliable and valid system in order to reduce fall risk in hemodialysis patients.
Brief Paper - Exponential stability of impulsive positive systems with mixed time-varying delays

This study addresses the problem of exponential stability for a class of impulsive positive systems with mixed time-varying delays. A delayed impulsive positive system model is introduced for the first time and a necessary and sufficient condition guaranteeing the positivity of this kind of system is proposed. By using a copositive Lyapunov–Krasovskii functional and the average impulsive interval method, a sufficient criterion of global exponential stability for delayed impulsive positive systems is established in terms of linear programming problems. A numerical example is given to show the effectiveness of the proposed method.
Numerical Study on the Various Profile Sections of Concrete Filled Steel Tubular Columns Under Compression

The axial load-carrying capacity for a wide range of short concrete-filled steel tubular (CFST) members having different section profiles is evaluated in the presented work. A numerical study has been carried out through Finite-Element based demonstration and it has been accomplished in the ABAQUS package for relevancy of analytically predicted axial load carrying capacity by unified formula as suggested by Yu M. et al. (2010). To validate the results from the unified formula and the experimentally available literature, finite element-based models for hollow and solid sections of CFST columns with circular, octagonal, and square section profiles have been generated. A total of 31 hollow and 24 solid circular columns, 9 hollow, and 9 solid octagonal columns, and in the last 9 hollows and 38 solid square CFST columns are examined for the persistence of the results. After evaluation of obtained results from the modeling existing results are validated, and it is found that the proposed unified formula predicts satisfactory results when compared with the result of established models. Further, it is concluded that displacement in the direction of applied load is not uniform throughout the length of CFST columns thereby using the ring confinement technique for the region of applied force may be reasonable.
Behavioral responses of different reproductive statuses and sexes in Hermetia illucens (L) adults to different attractants

Background The odor of various fermented organic materials acts as an attractant for oviposition by gravid females of the black soldier fly (BSF) to find larval food sources. Females display oviposition site selection on various organic materials, but little work has been done on the response to substrate attractants under caged conditions similar to those in a BSF farm production system. Methods Fifty of each reproductive status (mated and virgin) and sex (males and females) of BSF adults were marked and then exposed to one of five different oviposition attractants in a transparent acrylic chamber: no substrate (control) plus pineapple, mixed vegetables, okara, and fermented fish to represent fruit-, vegetable-, plant protein-, and animal protein-based substrates, respectively. The frequency of the perching activity on the oviposition apparatus and flying behavior under the LED illumination, including the laid egg weight, were recorded. Results The sexually-related activities of BSF adults were clearly observed. A majority of the females preferred to perch on the oviposition apparatus and fly around the illuminated area compared to the very low activities of the mated males. The BSF adults displayed different behavioral responses to the different tested attractants. While active flying was common when using plant protein- and animal protein-based substrates, mated females showed the greatest perching preference for plant-based substrates (fruit and vegetables) and this correlated with the laid egg weight. Discussion Egg-laying was more likely to happen on the plant-based substrate than on the animal protein-based substrate. However, the strong smell of the animal protein-based substrate could strongly trigger lekking behavior, which is an important part of mating behavior. This knowledge can support egg trapping in nature and also improve the efficiency of egg production in mass-rearing facilities.
On $G$-disconnected injective models

Si G est un groupe fini, L.S. Scull a observe que la definition originale de la minimalite equivariante n'est pas correcte dans le cas G-connexe par suite d'une erreur concernant des proprietes algebriques. Dans le cas G-non connexe, la categorie des orbites O(G) a ete remplacee par la categorie O(G, X), avec un objet pour chaque composante des sous-ensembles simpliciaux de points fixes X H d'un ensemble G-simplicial X, pour tous les sous-groupes H C G. Nous redefinissons la minimalite equivariante et redeveloppons des resultats d'homotopie rationnelle pour les ensembles G-simpliciaux non connexes. Pour montrer l'existence d'un modele minimal injectif M X pour un ensemble G-simplicial X non connexe, nous remplacons O(G,X) par la categorie plus subtile O(G,X) avec un objet pour chaque 0-simplexe de sous-ensembles simpliciaux de points fixes X H , par tous les sous-groupes H C G.
Towards the gravity/CYBE correspondence — the current status —

We give a brief summary of Yang-Baxter deformations of the AdS5 × S5 superstring by focusing upon four examples, 1) gravity duals for noncommutative gauge theories, 2) γ-deformations of S5, 3) Schrödinger spacetimes and 4) abelian twists of the global AdS5.
Angle-dependent time delay in two-color XUV+IR photoemission of He and Ne

We solve the time-dependent Schrödinger equation for a noble gas atom (He and Ne) driven by an ionizing XUV and dressing IR fields. From this solution we deduce an angular dependence of the photoemission time delay as measured by the RABBITT (reconstruction of attosecond beating by interference of two-photon transitions) technique. We use a recent angle-resolved RABBITT measurement on helium [S. Heuser et al., Phys. Rev. A 94, 063409 (2016)] to test and calibrate our theoretical model. Based on this calibration, we find no significant difference between the time delay in He measured in the angle-integrated RABBITT experiments [C. Palatchi et al., J. Phys. B 47, 245003 (2014) and D. Guénot et al., ibid. 47, 245602 (2014)] and measured or calculated in the polarization axis direction. The angular dependence of the photoemission time delay of Ne is shown to be qualitatively different from He because of the different orbital character of the valence 2p orbital. The angular momentum projection dependence of the time delay in Ne is also investigated.
A luminescence-based method to assess antigen presentation and antigen-specific T cell responses for in vitro screening of immunomodulatory checkpoints and therapeutics

Investigations into the strength of antigen-specific responses in vitro is becoming increasingly relevant for decision making in early-phase research of novel immunotherapeutic approaches, including adoptive cell but also immune checkpoint inhibitor (ICI)-based therapies. In the latter, antigen-specific rapid and high throughput tools to investigate MHC/antigen-specific T cell receptor (TCR) activation haven’t been implemented yet. Here, we present a simple and rapid luminescence-based approach using the human papillomavirus 16 (HPV16) E711-20 peptide as model antigen and E7-TCR transgenic Jurkat.NFAT-luciferase reporter cells. Upon E7 peptide pulsing of HLA-A2+ cell lines and macrophages, an effector to target ratio dependent increase in luminescence compared to non-pulsed cells was observed after co-incubation with E7-TCR expressing Jurkat, but not with parental cells. Analogous experiments with cells expressing full-length HPV16 identified that E7-specific activation of Jurkat cells enabled detection of endogenous antigen processing and MHC-I presentation. As proof of concept, overexpression of established checkpoints/inhibitory molecules (e.g., PD-L1 or HLA-G) significantly reduced the E7-specific TCR-induced luminescence, an effect that could be restored after treatment with corresponding targeting antagonistic antibodies. Altogether, the luminescence-based method described here represents an alternative approach for the rapid evaluation of MHC-dependent antigen-specific T cell responses in vitro. It can be used as a rapid tool to evaluate the impact of the immunosuppressive tumor microenvironment or novel ICI in triggering effective T cell responses, as well as speeding up the development of novel therapeutics within the immune-oncology field.
On the Absorber in Gravitation

Mach’s principle states in a very general manner: local physical laws are determined by the large scale structure of the universe. This principle is the basis of the Wheeler-Feynman absorber theory [1, 2]. They suppose that the energy of particles is given by a time-symmetrical field; this interpretation was made by Tetrode and assumes that particles are not selfinteracting. The main equations go as follows:
A WhatsApp Application-Based Therapy for Adolescents with Depression

In providing a therapy treatment to a patient with depression, the communication between a psychiatric doctor and a patient with depression must not be limited solely during the therapy session. Therefore, this study aims to identify the appropriate mobile application according to the types of depression therapy that require mobile application-based therapy for adolescents with depression. The participants in this study were recruited based on purposive sampling. The first round which consisted of four psychiatric doctors involved two males and two females participating in this study followed by participation of 14 experts in the second round. This study which employed the Fuzzy Delphi Method revealed that Whatsapp is necessary and thus categorized as the main based–therapy for adolescents with depression and Cognitive Behavioural Therapy has been acknowledged as the most suitable type of depression therapy that needs mobile application-based therapy for adolescents with depression. This method is useful to design a particular based-therapy module for the doctors to use in mobile application for adolescents with depression. The results of this study would be useful for doctors, particularly in using Whatsapp as a based therapy to interact with adolescents with depression in the future.
Tensor products of measurable operators

We introduce and study a stability property for submodules of measurable operators and Calkin spaces and characterize the tensor stable singly generated Calkin spaces. Given semifinite von Neumann algebras (M, τ), (N , σ) and corresponding measurable operators S, T , we provide a necessary and sufficient condition for the operator S ⊗ T to be measurable with respect to (M⊗N , τ ⊗ σ).
Evidence from reaction times for an anticipatory process in symbolic delayed matching-to-sample

It was predicted that a delay between sample offset and comparison onset in symbolic delayed matching-to-sample (DMTS) would allow time for the anticipatory retrieval of the correct comparison so that the match/no match status of the presented comparison could be decided more swiftly. The relation between delay and reaction time (RT) was explored in participants after they had been similarly tested, as a control, on identity DMTS using the same stimuli. In most participants there was the predicted inverse relation between delay and RT in symbolic DMTS, but no such relation in identity DMTS. Subsequently an arithmetic test, designed to allow a simple calculation before or after presentation of the comparison, was used to demonstrate an analogous effect of a delay on RT.
Pd-Based Nano-Catalysts Promote Biomass Lignin Conversion into Value-Added Chemicals

Lignin, as a structurally complex biomaterial, offers a valuable resource for the production of aromatic chemicals; however, its selective conversion into desired products remains a challenging task. In this study, we prepared three types of Pd-based nano-catalysts and explored their application in the depolymerization of alkali lignin, under both H2-free (hydrogen transfer) conditions and H2 atmosphere conditions. The materials were well characterized with TEM, XRD, and XPS and others, and the electronic interactions among Pd, Ni, and P were analyzed. The results of lignin depolymerization experiments revealed that the ternary Pd-Ni-P catalyst exhibited remarkable performance and guaiacols could be produced under H2 atmosphere conditions in 14.2 wt. % yield with a selectivity of 89%. In contrast, Pd-Ni and Pd-P catalysts resulted in a dispersed product distribution. Considering the incorporation of P and the Pd-Ni synergistic effect in the Pd-Ni-P catalyst, a possible water-involved transformation route of lignin depolymerization was proposed. This work indicates that metal phosphides could be promising catalysts for the conversion of lignin and lignin-derived feedstocks into value-added chemicals.
Coherent Synchrotron Radiation and Microwave Instability in Electron Storage Rings

This thesis work was dedicated to investigating coherent synchrotron radiation (CSR) and microwave instability (MWI) in electron rings. CSR is an important issue in modern electron/positron storage rings, where short bunch length and/or low emittance are usually desired for particle physics or to produce light. To better understand the physics of CSR, we developed a new code, CSRZ, for calculating CSR impedance for an arbitrarily curved chamber. The chamber has rectangular cross section. The CSR impedance can be calculated with boundary conditions of perfectly conducting walls or resistive walls. With low-level numerical noises and minimal numerical damping, the code is well suitable for the task of calculating CSR impedance in a series of bending magnets. With a tiny approximation on the geometry of the chamber, which was assumed to be wiggling in the code, CSRZ can also be used to calculate the longitudinal impedance due to coherent radiation in a wiggler (CWR). Therefore, CSRZ does fulfill another mission of calculating the CWR impedance in the wiggler sections of KEKB and SuperKEKB. An analytic eigenfunction expansion method was available to calculate the longitudinal impedance due to CWR with rectangular chamber. The method used dyadic Green’s functions in electromagnetic theory and was rigorous for the case of straight chamber. Substantial alterations were performed in order to make it applicable to calculate the imaginary part of CWR impedance related to the beam self-fields. Therefore we re-derived the theory and did find the full expressions for CWR impedance. With shielding of chamber, the CWR impedance indicates resonant properties which were not seen in the theory for CWR in free space. The analytic work also provides excellent benchmarking to the CSRZ code. The last part of this thesis addresses microwave instability (MWI) in the KEKB low energy ring (LER) and the SuperKEKB positron damping ring (DR). Code development for simulating MWI was discussed first. For the KEKB LER, the impedances of various components, including CSR, were collected and used to survey the MWI. The CSR instability in the SuperKEKB DR was studied using existing theories of instability analysis. This thesis is dedicated to my family, especially . to my parents for bringing me to this world and for always encouraging me to follow my dreams, to my wife, Mingyu Han, for her love, unlimited support and understanding.
Bipolar Androgen Therapy: When Excess Fuel Extinguishes the Fire

Androgen deprivation therapy (ADT) remains the cornerstone of advanced prostate cancer treatment. However, the progression towards castration-resistant prostate cancer is inevitable, as the cancer cells reactivate androgen receptor signaling and adapt to the castrate state through autoregulation of the androgen receptor. Additionally, the upfront use of novel hormonal agents such as enzalutamide and abiraterone acetate may result in long-term toxicities and may trigger the selection of AR-independent cells through “Darwinian” treatment-induced pressure. Therefore, it is crucial to develop new strategies to overcome these challenges. Bipolar androgen therapy (BAT) is one such approach that has been devised based on studies demonstrating the paradoxical inhibitory effects of supraphysiologic testosterone on prostate cancer growth, achieved through a variety of mechanisms acting in concert. BAT involves rapidly alternating testosterone levels between supraphysiological and near-castrate levels over a period of a month, achieved through monthly intramuscular injections of testosterone plus concurrent ADT. BAT is effective and well-tolerated, improving quality of life and potentially re-sensitizing patients to previous hormonal therapies after progression. By exploring the mechanisms and clinical evidence for BAT, this review seeks to shed light on its potential as a promising new approach to prostate cancer treatment.
Low-Rank Sparse Generative Adversarial Unsupervised Domain Adaptation for Multitarget Traffic Scene Semantic Segmentation

Semantic segmentation in diverse real-world traffic scenes is a challenging task for autonomous vehicles to have a reliable understanding of the outside environment. Although deep visual models show a remarkable performance on traffic scene segmentation, they need significant improvements when the source and target scene distributions are different. The weather and illumination differences between source and target datasets result in dramatic distribution shifts that degrade the target segmentation performance. This article develops an unsupervised domain adaptation (UDA) model to address complex domain shift problems where the dataset, weather, and illumination of source and target traffic scenes are different. We devise a sparse adversarial multitarget UDA approach to capture powerful domain-invariant features to segment traffic scenes in different conditions. First, a sparse representation of the source traffic scenes is captured via a new spectral low-rank dictionary learning technique in the latent space of a deep encoder–decoder segmentation architecture. The feature sparsity provides high generalization capacity for our deep feature extractor that enables us to compute complex visual patterns of source images. Then, the distribution of source sparse features is learned using a generative adversarial framework. Finally, the sparse representations of source and target scenes are aligned via a sparse domain-invariant feature extractor trained by min–max optimization. The aligned features serve as domain-invariant scene representations that can best describe both source and target scenes; hence providing deep domain adaptation for traffic scene semantic segmentation. Experiments on a real-world dataset indicate the superiority of the proposed model compared to the state-of-the-art methodologies.
How does CEO social class perception impact employee-related CSR? Evidence from privately owned Chinese firms

Abstract Despite recent progress, the literature is still unclear on the internal determinants of employee-related corporate social responsibility (CSR), particularly regarding the effect of the chief executive officer (CEO). Integrating upper echelons theory with the social class literature, this study examines how CEO social class perception influences private firms’ employee-related CSR. Based on a unique dataset from the Nationwide Private Firms Survey of China, this study empirically shows that higher CEO social class perception promotes a higher level of employee-related CSR activities in private firms. Additionally, this positive impact of CEO social class perception on employee-related CSR is amplified among younger firms and firms that face higher market munificence. Our study contributes to the current literature by enriching our understanding of the antecedents of employee-related CSR from the perspective of the CEO’s cognition of his or her social class and revealing the related informative boundary conditions.