Miracle-dz/UniFAR-FTUs huggingface dataset:
Elite screening and nutritional profiling of Syzygium caryophyllatum (L.) Alston -an underutilized fruit tree

ABSTRACT Syzygium caryophyllatum is an underutilized minor fruit tree that bears globular fruits. When they ripen, they turn a deep purple or black colour. Even though the fruits are edible, consumption is low due to the low proportion of edible parts and limited supply of fruits. In the present study, twenty collections of S. caryophyllatum from various parts of Kerala State, India, were evaluated based on morphological (qualitative and quantitative), and biochemical traits of fruits. The findings revealed a wide range of variation among the collections. Among the selected candidate plus trees (CPTs), one CPT, SC3, appeared as a distinct candidate from all other collections in the dendrogram based on quantitative and biochemical traits. The grouping pattern in cluster analysis results was supported by a scatter plot based on Principal coordinate Analysis (PCoA). Various fruit traits of SC3 showed superiority and thus this tree was selected as the most promising among 20 CPTs with maximum pulp percentage, pulp-to-seed ratio, TSS, anthocyanins, ascorbic acid, total sugar, and minimum seed percentage. The nutritional profiling of SC3 fruit showed a vital source of nutritious elements with antinutrient concentrations falling within the acceptable range.
Two servers in series, studied in terms of a Markov renewal branching process

This paper discusses the transient and limiting behavior of a system of queues, consisting of two service units in tandem in which the second unit has finite capacity. When the second unit reaches full capacity, a phenomenon termed “blocking” occurs. A wide class of rules to resolve blocking is defined and studied in a unified way. The input to the first unit is assumed to be Poisson, the service times in the first unit are independent with a general, common distribution. When the system is not blocked, the second unit releases its customers according to a state-dependent, death process. The analysis of the time-dependence relies heavily on several imbedded Markov renewal processes. In particular, the analog of the busy period for the M/G/1 queue is modeled here as a “Markov renewal branching process”. The study of this process requires the definition of a class of matrix functions which generalizes some classical definitions of matrix function. In terms of these “matrix functions” we are led to consider functional iterates and a matrix analog of Takács' functional equation for the transform of the distribution of the busy period in the M/G/1 model. We further discuss the joint distribution of the queue lengths in units I and II and its marginal and limiting distributions. A final section is devoted to an informal discussion on how the numerical analysis of this system of queues may be organized.
A general fixed point theorem for a pair of multi-valued mappings in partial metric spaces

Abstract The purpose of this paper is to prove a general fixed point theorem for a pair of multi-valued mappings satisfying a new type of implicit relation in partial metric spaces, which generalizes Theorem 2.2 [4], Theorem 3.1 [3], Theorem 3.2 [7], Corollary 2.3 [4], Theorem 2.8 [16] and obtain other particular results.
Immunochromatography screening devices for cannabinoids in oral fluid sample

consumed drugs in the world and recent studies have associated its use with an increase in the number of traffic accidents in different countries. In many countries, like Brazil, simple and reliable methodologies are still needed for the detection of drugs on site, mainly cannabinoids, considering its prevalence of use and oral fluid (OF) has been proved as an appropriate biological matrix for this purpose. Considering that, this work aims to review previous studies on immunochromatographic devices for on-site detection of cannabinoids in OF, discussing their sensitivity, specificity, cut-offs values and confirmatory methods. This data shows the importance of choosing a screening device and it reinforces the need for its implementation in Brazil. The research was conducted on 5 databases and all original articles, published in the last 10 years, were selected. A total of 32 articles were found, providing data for 17 screening devices of distinct brands. Only 2 screening devices showed satisfactory sensitivity and specificity in the evaluated studies (≥80% and ≥90% respectively). However, it should be considered that the screening devices still have some limitations, such as a higher cut-off than those recommended by international guidelines (cut-off > 2 ng/mL), therefore demonstrating the need for more studies in the area and the importance of confirmatory analysis usually fulfilled by LC-MS/MS, GC-MS/MS or GC-MS. Thus, the screening analyzes should not be evaluated by itself, but in association with confirmatory results and observational traits (behavioral changes), for a better understanding of the traffic scenario.
PENGARUH BRAND EXPERIENCE TERHADAP BRAND LOYALTY DENGAN CUSTOMER ENGAGEMENT SEBAGAI VARIABEL MEDIATOR PADA PRODUK FASHION DI INDONESIA

Tujuan dalam penelitian yaitu untuk menganalisis pengaruh dimensi brand experience, customer engagement yang mempengaruhi brand loyalty konsumen produk fashion di Indonesia. Dengan melakukan penyebaran kuesioner kepada 132 responden, pegambilan sampel pada penelitian ini menggunakan non-probabilitas sampling dan purposive sampling. Metode analisis data menggunakan structural equation modeling (SEM) dan software AMOS22. Hasil menampilkan variabel sensory brand experience berpengaruh positif terhadap brand engagement. Kemudian affective brand experience, behavioral brand experience, intellectual brand experience mempengaruhi positif juga signifikan terhadap customer engagement dan customer engagement mempengaruhi positif juga signifikan terhadap customer loyalty. Adapun saran bagi perusahaan fashion di Indonesia adalah meningkatkan sensory brand experience, affective brand experience, behavioral brand experience, intellectual brand experience untuk konsumen agar konsumen dapat terlibat dan loyal terhadap merek.
Use, Validity and Reliability of Inertial Movement Units in Volleyball: Systematic Review of the Scientific Literature

The use of inertial devices in sport has become increasingly common. The aim of this study was to examine the validity and reliability of multiple devices for measuring jump height in volleyball. The search was carried out in four databases (PubMed, Scopus, Web of Sciences and SPORTDiscus) using keywords and Boolean operators. Twenty-one studies were selected that met the established selection criteria. The studies focused on determining the validity and reliability of IMUs (52.38%), on controlling and quantifying external load (28.57%) and on describing differences between playing positions (19.05%). Indoor volleyball was the modality in which IMUs have been used the most. The most evaluated population was elite, adult and senior athletes. The IMUs were used both in training and in competition, evaluating mainly the amount of jump, the height of the jumps and some biomechanical aspects. Criteria and good validity values for jump counting are established. The reliability of the devices and the evidence is contradictory. IMUs are devices used in volleyball to count and measure vertical displacements and/or compare these measurements with the playing position, training or to determine the external load of the athletes. It has good validity measures, although inter-measurement reliability needs to be improved. Further studies are suggested to position IMUs as measuring instruments to analyze jumping and sport performance of players and teams.
Anti-Inflammatory and Anti-Adipogenesis Effects of Alchemilla vulgaris L., Salvia officinalis L., and Vitis vinifera L. in THP-1-Derived Macrophages and 3T3-L1 Cell Line

The production of pro-inflammatory and anti-inflammatory cytokines, as well as adipocyte differentiation and fat accumulation in the 3T3-L1 mouse embryo fibroblast cell line and the human monocytic cell line THP-1 were measured to determine the anti-inflammatory and antiadipogenic effects of ethanolic extracts of verjuice (unripe grape juice (Vitis vinifera L.)), Salvia officinalis L. , and Alchemilla vulgaris L. On both cell lines, the three extracts had much greater cytostatic effects than cytotoxic effects. With an IC50 of 505 μg/mL, S. officinalis had the highest cytostatic effect on THP-1-derived macrophages. After treatment with 125 μg/mL, the three extracts dramatically reduced the LPS-induced NO generation in THP-1-derived macrophages from 80 μM to control values after treatment with 125 µg/mL. Furthermore, the extracts reduced the levels of TNF-α and IL-6 production in a dose-dependent manner with the highest effects reached at 250 µg/mL. The production of TNF-α decreased at higher levels compared to IL-6 production. V. vinifera, S. officinalis, and A. vulgaris extracts improved the production levels of IL-10 from 32 pg/mL to 86 pg/mL, 98 pg/mL, and 80 pg/mL at an extract concentration of 125 µg/mL, respectively. The adipocyte differentiation and fat accumulation in 3T3-L1 were decreased to 20% of control values after treatment with plant extracts. Taken together, these results suggest that V. vinifera, S. officinalis, and A. vulgaris likely exert their anti-obesity effects through cytostatic actions and modulation of pro-inflammatory and anti-inflammatory cytokine production, as well as by reducing adipocyte differentiation and fat accumulation.
The Correlation Between the Number of Hours Spent on Reading and Language Competence Gained

In academia, there is a sort of hidden argument about the factors which shape effective reading and the amount of language competence gained through reading. In this regard, few believe that the number of the hours spent daily on reading different sources will lead to effective reading and high language competence regardless of the fact that how this amount of time is spent. On the contrary, some believe that the number of hours has nothing to do with effective reading and this time measurement criterion has no validity in relation to effective reading and the development of specialized language competence. Accordingly, the present paper tried to consider the essential factors which lead to effective reading and the development of specialized competence. Moreover, it aimed at providing evidence of the fact that high specialized language competence is basically the result of effective reading rather than the number of hours spent on reading something.
Van Der Corput's Lemma in Number Theory and Analysis and its Applications to Abelian Varieties with Prescribed Groups

Let A be an Abelian variety over a finite field Fq. We are interested in knowing the distribution of the groups A(Fq) of rational points on A as we run over all varieties defined over Fq. In particular, we want to show that they are in general not too "split". For the case of dimension 1 (elliptic curves) and dimension 2 (Abelian surfaces), there are some theoretical results due to David and her collaborators, but the general case is open. We are interested in Abelian Varieties of dimension 3. We use Rybakov's criterion, which relates the existence of a given abstract group as the group of points of some Abelian variety to properties of the characteristic polynomial of the variety. We can use it to derive precise properties and then we use the fact that some sequence of monomials of five variables is uniformly distributed modulo one to obtain stronger results that will hold with probability one. By Weyl's criterion, equidistribution follows by bounding exponential sums, and in order to do so, we will use a combination of different methods. We are particularly interested in Van Der Corput's lemma. It has a continuous version that exhibits the decay of oscillatory integrals and a discrete version that gives a bound for exponential sums. We will see the relation between these two versions and how they apply to the original problem of Abelian varieties.
Pre-fortis Clipping Patterns: A Cross Linguistic Examination of L2 English Production and Perception by Asian Learners of English

In English, it is widely observed that vowels are longer before voiced consonants than before voiceless ones such as English. However, in Mandarin Chinese, Vietnamese, Japanese, and Korean, the distribution of voiced-voiceless stop contrasts, and long-short vowel differences are vastly different from English. The purpose of this study is to determine whether these targeted learners’ L2 English production and perception change in terms of vowel duration as a function of stop voicing. The production measurements in the database of Asian learners revealed a distinct effect than the one observed in native speakers. There were no evident vowel lengthening patterns. The results of the perceptual experiment with 24 participants indicated that individuals tended to prefer voiceless stops when preceding vowels were shortened, but there was no statistically significant difference between intermediate, upper-intermediate, and advanced-level learners. However, learners demonstrated distinct perceptual patterns for various vowels and stops. The findings have valuable implications for L2 English speech acquisition.
TOTALLY QUASI-UMBILIC TIMELIKE SURFACES IN R 1;2

For a regular surface in Euclidean space R 3 , umbilic points are precisely the points where the Gauss and mean curvatures K and H satisfy H 2 = K; moreover, it is well- known that the only totally umbilic surfaces in R 3 are planes and spheres. But for timelike surfaces in Minkowski space R 1;2 , it is possible to have H 2 = K at a non-umbilic point; we call such points quasi-umbilic, and we give a complete classication of totally quasi-umbilic timelike surfaces in R 1;2 .
Optimization with Sparsity-Inducing Penalties (Foundations and Trends(R) in Machine Learning)

Sparse estimation methods are aimed at using or obtaining parsimonious representations of data or models. They were first dedicated to linear variable selection but numerous extensions have now emerged such as structured sparsity or kernel selection. It turns out that many of the related estimation problems can be cast as convex optimization problems by regularizing the empirical risk with appropriate nonsmooth norms. Optimization with Sparsity-Inducing Penalties presents optimization tools and techniques dedicated to such sparsity-inducing penalties from a general perspective. It covers proximal methods, block-coordinate descent, reweighted 2-penalized techniques, working-set and homotopy methods, as well as non-convex formulations and extensions, and provides an extensive set of experiments to compare various algorithms from a computational point of view. The presentation of Optimization with Sparsity-Inducing Penalties is essentially based on existing literature, but the process of constructing a general framework leads naturally to new results, connections and points of view. It is an ideal reference on the topic for anyone working in machine learning and related areas.
Comparing the Effectivity of Intravenous Analgetic Tramadol and Intravenous Paracetamol for Acute Post-Percutaneous Nephrolithotomy

There are many management strategies and interventions both preoperative, intraoperative, and postoperative that can be carried out in dealing with postoperative pain. Guidelines for pain management have been prepared by the American Pain Society (APS) with recommendations from the American Society of Anesthesiologists (ASA) where there are many recommendations in postoperative pain management in adults or children by promoting the provision of preoperative education, the use of various modalities both pharmacological and non-pharmacological to the establishment of pain management procedures or policies in each institution. For this reason, the author was interested in examining the comparison of the effectiveness of analgesia between intravenous tramadol and intravenous Paracetamol in minimally invasive Percutaneous Nephrolithotomy (PCNL) postoperative patients at RSUP Dr. M. Djamil Padang. The research was a prospective study with a single-blind randomised controlled trial design. The data used were sourced from clinical trials conducted on post-PCNL patients divided into two subgroups given intravenous tramadol analgetics and others given Paracetamol tablets. In this study, the incidence of Nephrolithiasis was obtained, which was dominated by the male sex, compared to women and suffered a lot at the age of 41-60 years. There was a significant difference in VAS effectiveness between the use of Paracetamol IV and Tramadol IV in post-PCNL patients. The use of Paracetamol may be considered to replace tramadol in the disappearance of acute pain after PCNL postoperative patients in those patients who are allergic to tramadol.
Comparative Study Between Non-Diffractive Extended Depth of Focus and Monofocal Intraocular Lenses

Purpose To evaluate the visual acuity and quality of vision in bilaterally implanted ZCBOO/ZCTx monofocal (Johnson & Johnson Vision) intraocular lens (IOL) and bilaterally implanted DATx15 extended depth of focus (EDOF) IOL (Alcon Vision, LLC). Methods A single site, non-interventional study comparing ZCBOO/ZCTx monofocal IOL patients implanted with DATx15 IOL toric or non-toric versions in both eyes. A total of 30 patients (60 eyes) completed the study in the monofocal group, 32 (64 eyes) in the EDOF group, and all were targeted for emmetropia. Binocular uncorrected distance, intermediate (66cm), and near (40cm) visual acuities and distance corrected distance, intermediate (66cm) and near (40cm) visual acuities were assessed. Binocular distance corrected defocus curve testing was from −3.5 D to +3 D. Patient reported visual disturbances (QUVID) and IOL satisfaction (IOLSAT) questionnaires were administered. Results The DATx15 group mean uncorrected visual acuity was 0.15 ± 0.10 logMAR at 66cm and 0.36 ± 0.14 logMAR at 40cm, compared to 0.24 ± 0.15 logMAR and 0.59 ± 0.17 logMAR respectively for the ZCBOO/ZCTx group. The DATx15 group (23 respondents, 74%) also reported significantly more spectacle independence at near with the IOLSAT (p < 0.01), compared to the ZCBOO/ZCTx group (13 respondents, 43%). Glare, halos, starbursts, and blur reported on the QUVID questionnaire were similar in the two groups. Conclusion The DATx15 group had improved near and intermediate vision and increased spectacle independence compared to the ZCBOO/ZCTx group.
Disentangling environmental effects on plant disease epidemics at the regional scale

The environment plays an essential role in driving the occurrence and dynamics of plant disease epidemics. The weather is known to influence pathogen and host biology and should modulate the stages of the disease cycle. On the other hand, climate, the average of weather within long periods of time (i.e. 30 years), should set the predominance of pathogens and host genotypes across regions, and therefore the spatial distribution of plant diseases and their respective intensities. In this thesis, three studies aiming to unravel the effects of environmental factors on plant disease epidemics will be presented. The first study will demonstrate how the climate shapes the spatial distribution of citrus Huanglongbing prevalence in Minas Gerais. In the second study, the time to onset of soybean rust in commercial soybean fields from Southern Brazil was associated with the El Nino Southern Oscillation, a phenomenon that triggers extreme weather events around the globe and also in Brazil; The third study integrates cutting- edge statistical methodology to associate weather time series and soil properties data to white mold prevalence in snap bean fields in New York, United States. The results led to novel insights into pathogen biology and disease risk at the regional and local scales for the three pathosystems under study. Keywords: Epidemiology. Huanglongbing. Soybean rust. White mold. Bayesian. Machine learning.
Multi-Omics Unravels Metabolic Alterations in the Ileal Mucosa of Neonatal Piglets Receiving Total Parenteral Nutrition

Total parenteral nutrition (TPN) is life-saving therapy for the pediatric patients with intestinal failure (IF) who cannot tolerate enteral nutrition (EN). However, TPN-induced metabolic alterations are also a critical issue for the maintenance of intestinal homeostasis, and thus the global metabolomic signatures need to be addressed. In this study, ileal mucosal biopsies were collected from 12 neonatal Bama piglets receiving either EN or TPN for 14 days, and changes in the intestinal metabolism were examined by multi-omics (HM350 Metabolomics + Tandem Mass Tag (TMT)-based proteomics). As a result, a total of 240 compounds were identified by metabolomics, including 56 down-regulated and 9 up-regulated metabolites. Notably, tissue levels of fatty acyl-carnitines (decreased by 35–85%) and succinate (decreased by 89%) dramatically decreased in the TPN group, suggestive of disrupted processes of fatty acid oxidation (FAO) and the citrate cycle, respectively. Interestingly, however, no differences were found in the production of adenosine 5′-triphosphate (ATP) between groups, suggesting that these dysregulated metabolites may have mainly led to the loss of bioactive compounds rather than energy deficit. Additionally, 4813 proteins were identified by proteomics in total, including 179 down-regulated and 329 up-regulated proteins. The analysis of protein–protein interactions (PPI) indicated that most of the differentially expressed proteins were clustered into “lipid metabolism” and “innate immune responses”. In summary, this work provided new findings in TPN-induced intestinal metabolic alterations, which would be useful to the improvement of nutritional management for IF patients.