Miracle-dz/UniFAR-FTUs huggingface dataset:
WARM- ASPHALT MIXTURES MODIFIED WITH SUPERPLAST

Moisture and stripping damages are the most prevalent cause of defects of both Hot-Mix Asphalt (HMA) and Warm-Mix Asphalt (WMA). Adhesion between aggregates and bitumen is a crucial factor that affects such defects. Various methods, such as incorporating additives, have strengthened the asphalt mixture's resistance to moisture and stripping. This paper aimed to experimentally investigate the effect of including a low-cost polymer additive (Superplast) into HMA and WMA mixtures. For this goal, a 60/70 penetration grade bitumen was used. For preparing the WMA mixtures, Showax was employed with percentages of 2, 3, 4, 5, and 6% by weight of bitumen. Polymer modified mixtures (HMA and WMA) were prepared by adding 3%, 4, and 5% 680 Ghada S. Moussa et al., Performance Investigation of HotAnd WarmAsphalt Mixtures . of Superplast by weight of the binder. Performance characterizations of the unmodified and Superplast-modified mixtures include stiffness, moisture damage resistance, and bonding. These characteristics were evaluated via Marshall, Lottman, and Double Punching tests, respectively. Results revealed that incorporating Superplast improved the adhesion between bitumen and aggregates, which ultimately led to an increase in the stiffness and moisture resistance of both HMA and WMA. Moreover, Superplast-modified WMA mixtures exhibited the best moisture and stripping resistance performance compared to Superplast-modified HMA and other unmodified mixtures.
Multiarea Economic Dispatch Using Evolutionary Algorithms

Multiarea economic dispatch (MAED) is a vital problem in the present power system to allocate the power generation through dispatch strategies to minimize fuel cost. In economic dispatch, this power generation distribution always needs to satisfy the following constraints: generating limit, transmission line, and power balance. MAED is a complex and nonlinear problem and cannot be solved with classical techniques. Many metaheuristic methods have been used to solve economic dispatch problems. In this study, the dynamic particle swarm optimization (DPSO) and grey wolf optimizer (GWO) have been used to solve the MAED problem for single-area 3 generation units, a two-area system with four generating units, and four areas with 40-unit system. The hunting and social behaviors of grey wolves are implemented to obtain optimal results. During the optimization search, this algorithm does not require any information regarding the objective function’s gradient. The tunable parameters of the original PSO that are three parameters are dynamically controlled in this work that provides the efficient cost values in less execution time although satisfying all the MAED problem’s diverse constraints. In this study, the authors also implemented the GWO algorithm with two tunable parameters, and its execution is straightforward to implement for the MAED problem.
Testing the relationships between narcissism, risk attitude, and income with data from a representative German sample

Narcissism is related to income and risk-taking behavior, but previous studies have computed only pairwise associations and have used only domain-specific risk-taking measures. We jointly investigated narcissistic admiration and rivalry, income, and general risk attitude. Using a representative sample from the German population (N = 14,473), we contrasted a model assuming that risk attitude and narcissistic admiration and rivalry share variance when predicting income and a model with additive effects of narcissism and risk attitude. We found stronger effects of admiration on risk attitude and income than of rivalry and no evidence that risk attitude and narcissism share variance when predicting income. Contrary to previous studies, we found that an individual's income was independent of their risk attitude. In exploratory analyses (Response Surface Analysis, Level-and-Difference-Approach), we found that the relative strength of admiration compared with rivalry positively predicted risk attitude and income. Taken together, our findings are consistent with the hierarchical model of grandiose narcissism.
COPD_A_321877 2503..2513

1Department of Pulmonary and Critical Care Medicine, The First Affiliated Hospital of Jinan University, Guangzhou, 510630, People’s Republic of China; 2Department of Pulmonary and Critical Care Medicine, Lu’an People’s Hospital of Anhui Province, Lu’an, 237016, People’s Republic of China; 3Department of Endocrinology, Guangzhou Red Cross Hospital, The Affiliated Hospital of Jinan University, Guangzhou, 510220, People’s Republic of China Purpose: Chronic obstructive pulmonary disease (COPD) is associated with a complex inflammatory regulatory network. Resistin-like molecule β (RELMβ) is highly expressed in the lungs of COPD patients. We aimed to investigate the proinflammatory effect of RELMβ on airway epithelial cells in COPD. Methods: First, a GEO dataset was used to analyze the expression of the RELMβ gene in the COPD and control groups as well as the protein levels of RELMβ in the sera of outpatients with COPD and normal control subjects in our hospital. We also stimulated 16HBE bronchial epithelial cells with recombinant RELMβ protein and analyzed the expression of IL-8 and IL-1β. We upregulated and downregulated the gene expression of RELMβ in 16HBE cells and analyzed the expression of the inflammatory cytokines IL-8 and IL-1β. In addition, we also examined the mechanism by which the p38 MAPK signaling pathway contributed to the regulation of IL-8 and IL-1β expression by RELMβ. Results: RELMβ expression was increased in COPD tissues in different data sets and in the serum of COPD patients in our hospital. IL-8 and IL-1β expression was also increased in COPD tissues with high RELMβ gene expression in different data sets. The RELMβ gene was mainly related to inflammatory factors and inflammatory signaling pathways in the PPI regulatory network. Experiments at the cellular level showed that RELMβ promoted the expression of the inflammatory cytokines IL-8 and IL-1β, and this regulation was mediated by the p38 MAPK signaling pathway. Conclusion: RELMβ can promote the expression of the inflammatory cytokines IL-8 and IL-1β in bronchial epithelial cells of patients with COPD and exert inflammatory effects. RELMβ may be a potential target for the treatment of COPD.
FACTORS AFFECTING CITIZENS’ INTENTION TO CONTINUE USING THE REWARDING SOLID-WASTE COLLECTION MOBILE APPS IN TEHRAN, IRAN

Abstract. Despite technological advances in waste recycling and management, many developing countries, including Iran, are still in the early stages of this process: the segregation and collection of recyclable waste. In this regard, to increase citizens' coope ration in household waste segregation, a rewarding solid-waste collection system has been established in the metropolises of Iran. In such circumstances, it is evident that maintaining the continued use of citizens without compromising their satisfaction has become an essential concern in the development of a sustainable waste collection and recycling system in Iran. For this reason, the present study tries to investigate the factors affecting citizens' continuous intention to use the rewarding solid-waste collection (RSWC) mobile apps in Tehran (the capital of Iran). In this regard, first, the conceptual model of the research is obtained by combining the widely used ECM model with D&M’s IS success model. Then, the questionnaire designed based on previous studies was provided to the citizens, and out of a total of 373 completed questionnaires, by removing the incomplete ones, 302 questionnaires were finally analysed. A partial least squares (PLS) analysis based SEM using SmartPLS was performed to assess the model and verify hypotheses. Results show that various variables significantly influence users’ continuous intention to use RSWC mobile apps. Meanwhile, RSWC mobile apps should improve their platform quality and rewarding system, strengthen their content quantity, and ensure the consistency between their service and citizens’ satisfaction.
S-Allyl Cysteine Mitigates Kidney Dysfunctions in the Rat Models of Preeclampsia and Eclampsia: The Possible Role of TNF-α and IL1-β

Materials & Methods: Wistar rats were divided into seven groups: 1) control, 2) PE, 3) EC, 4) PE+SAC50, 5) PE+SAC200, 6) EC+SAC50, and 7) EC+SAC200. In Groups 1-3, the rats received saline by gavage for 9 consecutive days, starting on the day 11 of gestation (G11). In Groups 4-7, the rats received SAC (50 or 200mg/kg) by gavage for 9 days, starting on G11. The rats in PE and EC groups were injected with Lipopolysaccharides on G14. The rats in EC groups were injected with pentylenetetrazol (PTZ) on G16 and G18. On G20, urine, blood, and kidney samples were collected for biochemical analysis.
Evasion of Immune Surveillance in Low Oxygen Environments Enhances <named-content content-type='genus-species'>Candida albicans</named-content> Virulence

Microbial colonizers of humans have evolved to adapt to environmental cues and to sense nutrient availability. Oxygen is a constantly changing environmental parameter in different host tissues and in different types of infection. We describe how Candida albicans, an opportunistic fungal pathogen, can modulate the host response under hypoxia and anoxia. We found that high infiltration of polymorphonuclear leukocytes (PMNs) to the site of infection contributes to a low oxygen milieu in a murine subdermal abscess. A persistent hypoxic environment did not affect viability or metabolism of PMNs. Under oxygen deprivation, however, infection with C. albicans disturbed specific PMN responses. PMNs were not able to efficiently phagocytose, produce ROS, or release extracellular DNA traps. Failure to launch an adequate response was caused by C. albicans cell wall masking of -glucan upon exposure to low oxygen levels which hindered PAMP sensing by Dectin-1 on the surfaces of PMNs. This in turn contributed to immune evasion and enhanced fungal survival. The cell wall masking effect is prolonged by the accumulation of lactate produced by PMNs under low oxygen conditions. Finally, adaptation to oxygen deprivation increased virulence of C. albicans which we demonstrated using a Caenorhabditis elegans infection
EPIDEMIOLOGY AND TREATMENT OF FUNGAL INFECTIONS IN ONCO-PEDIATRIC PATIENTS AT A REFERRAL HOSPITAL

Aim: to identify the epidemiology of fungal infections in the pediatric service of a reference hospital for the treatment of cancer for 2016 to 2019, through the dispensing of antifungal drugs by the hospital pharmacy. Methods: Retrospective cohort analysis of 1.211 antifungal requests. Results and Discussion: 1.211 treatments with antifungal agents were performed in the period, with 71.9% of cases treated with empirical therapy, 64.1% of cases of mucocutaneous candidiasis and with the use of nystatin in 48.6% of cases. There were 114 episodes of IFIs, in which probable fungal pneumonia represented 40.4% of the therapeuticindications, based on suggestive tomographic images and clinical and epidemiological criteria in 40.3% of cases. Conclusions: There was an agreement between the epidemiology of fungal infections and the worldwide epidemiology, but there was disagreement between the therapies applied in the study hospital and the recent guidelines.
Assessment of the shaping ability of three systems used in long oval canals

The aim of this study was to analyze volume variation, untouched walls, transportation, and centralization in long oval canals prepared with ProTaper Next (PTN), X File (XF) and X Gray (XG) by microcomputed tomography (micro-CT). Forty-five lower incisors were divided into three groups (PTN, XF and XG) with 15 specimens each, according to the micro-CT pre-instrumentation (PI) analysis. After the use of each instrument new exams were performed. Volume variation and untouched walls data were analyzed by two-way ANOVA, and for the first one, Tukey HSD or Games-Howell tests were applied in the sequence; data of transportation and centralization were compared by Kruskal-Wallis and Mann-Whitney test. The statistical significance was set at p < 0.05. Between thirds, higher wear values were found in the cervical (p <0.001). PI and the instrument X3 (30/.07) differed in all systems (p < 0.05). No significant difference concerning the percentage of untouched walls between the systems occurred (p = 0.836), while the degree of transportation and centralization was similar between then, with p values of 0.531 and 0.155, respectively. However, between thirds, significant difference was found (pc = 0.029), with the middle third presenting superior centralization than the apical (p = 0.010). In conclusion, PTN, XF and XG had similar results in the shaping ability, transportation, and centralization of long oval canals.
Hormonal Physiological Changes of Testis Resulting From Exposure to Vinyl Cyanide and the Possible Protective Role of β-cryptoxanthin in Male Rat

Vinyl cyanide (VCN) is an aliphatic nitrile product which is extensively used in various synthetic chemical industries. VCN is known to exert toxic actions to human beings as well as experimental animals. The present study was designed to examine the ability of β-cryptoxanthin, a naturally occurring antioxidant, to attenuate VCN-induced testicular toxicity in adult albino rats. Daily oral administration of VCN at a dose level of 30 mg/kg b.w. (7.2mg/ animal) to male rats for a period of 5 days significantly reduced the levels of serum testosterone (T), androsterone, follicle-stimulating hormone (FSH) and luteinizing hormone (LH) which indicates injury to the testis function. Compared to VCN-treated animals, pretreatment with β-cryptoxanthin and its co-administration with VCN once daily at a dose of 40 mg/kg b.w. (9.6mg/ animal) for 30 days induced a remarkable degree of improvement in the levels of endocrine parameters including T, androsterone, FSH and LH. In conclusion, the present results clearly demonstrate the protective role of β-cryptoxanthin against VCN-induced physiological changes in the testis of rats.
Relationship Pattern of Fatherless Impacts to Internet Addiction, the Tendency to Suicide and Learning Difficulties for Students at SMAN ABC Jakarta

Fatherless is the absence of a father figure. Some impacts of fatherlessness are loneliness, openness, depression, self-control, and self-esteem. These factors can influence internet addiction and suicidal tendencies. It also can cause difficulty in the learning process for students. This study aims to determine the significant impacts caused by fatherlessness and the relation to internet addiction, suicidal tendencies, and learning difficulties. The method used is Partial Least Square. The results showed that the significant impacts caused by fatherlessness are loneliness, depression, and self-esteem. The impacts of fatherless that influence internet addiction are loneliness and depression. The impact of fatherlessness that influences suicidal tendencies is depression. Internet addiction and suicidal tendencies influence learning difficulties.
Determining Local Hematology Reference Ranges: A Data-driven Approach

Hematology is the study of blood, blood-forming organs, and blood diseases. Hematological tests such as Full Blood Count (FBC) can be used to diagnose a wide range of infections and diseases by comparing their results with the standard hematology reference (SHR) ranges. These ranges were established many years ago by considering the Caucasian population and all countries have used them until recent times to measure the healthiness of the people. But these reference ranges can be varied according to various reasons such as dietary habits, geographical location, climate, environmental factors, etc., and the use of them by all countries may not be correct. Many researchers have started research in finding Local Hematology Reference (LHR) ranges. Most of them used statistical analyses which have their limitations. Machine learning is a solution to overcome those limitations. Finding an approach to determine the LHR range based on machine learning techniques is the goal of this research. The dataset was generated using FBC test reports in Sri Lanka. The LHR range of WBC count of healthy adults in Sri Lanka is only addressed in this research. A difference between the SHR range of WBC and the LHR range of WBC is observed. Keywords—Hematology science; standard hematology reference range; domestic hematology reference ranges; local hematology reference range; machine learning; white blood cell count
Evaluation of Rutting and Fatigue Behaviors of Asphalt Binders Modified with Calcium Lignosulfonate

Asphalt mixes encounter different distress during the life cycle of asphalt pavements, among which rutting and fatigue failure are prominent. Moreover, the addition of environmentally friendly modifiers into the asphalt binder to increase the performance of asphalt mixes has been a challenging phenomenon for researchers. Calcium lignosulfonate (CL) is a waste material that is a by-product of the wood industry. In this paper, the impact of the calcium lignosulfonate on the rutting and fatigue performance of the asphalt binder was investigated. For this purpose, the Dynamic Shear Rheometer (DSR) was utilized to run the Multiple Stress Creep Recovery (MSCR) test and evaluate G ∗ /sinδ and G ∗ ·sinδ indices for the asphalt binder containing different percentages of CL. The elastic recovery test was also conducted on the asphalt binder. In order to analyze the thermal storage stability of CL-modified asphalt binders, the storage stability test was considered. The Field Emission Scanning Electron Microscope test showed that using CL as a binder modifier makes the texture of the asphalt binder spongy and porous. The conventional test results indicated that increasing the CL amount in the asphalt binder led to an increase in the stiffness of the asphalt binder. The rheological test results showed that the rutting resistance of the asphalt binder improved by adding up to 15% of the CL powder; however, the fatigue performance and the elasticity of the asphalt binder declined by increasing the CL content in the asphalt binder. The storage stability test revealed that the dispersion of CL in the asphalt binder was uniform; moreover, the presence of CL in the asphalt binder could not adversely affect the thermal storage stability of the modified asphalt binder.
The Effect of Management Strategy of ST Segment Elevation Myocardial infarction in Elderly on LV remodeling and Clinical Outcome

Acute ST-segment elevation myocardial infarction (STEMI) is the acute injury may evolve in the left ventricular remodeling despite effective coronary revascularization and optimal medical therapy and leads to advanced heart failure.The aim of the present study was to assess the effect of management strategy of ST segment elevation myocardial infarction in elderly on LV remodeling and clinical outcome.This study included 150 elderly patients above 60 years old with ST segment elevation myocardial infarction referred to the Coronary care unit, Benha University Hospital.They classified into 3 groups:patients who treated with conservative therapy(Group I),patients who treated with primary percutaneous intervention(Group II) and patients who treated with fibrinolytic therapy(Group III). Standard two-dimensional echocardiography,TDI derived velocity and speckle tracking and 3D echocardiography were used to assess LV remodeling and clinical outcome.Patients of group I were significantly older than those of group II and group III(p value˂0.001). Male gender was more prevalent in patients of 3 groups (P value ˂0.001). Early diastolic mitral annular velocity (e") was significantly reduced in patients of group I and group II compared with patients of group III(p value˂0.001) and the mitral E/e" ratio was significantly higher in patients of group I and group II compared with patients of group III (p value ˂ 0.001). There was no difference in management strategy of ST myocardial infarction patients as regarding conservative therapy, primary coronary intervention and fibrinolytic therapy.
The Life Cycle of Converging Industries: The Evolution of the Tablet Sector and Its Impact on Competitive Dynamics

Background of the study. In recent years a series of academic research projects in the economic managerial field have investigated the relationship between innovation and industrial evolution, providing new interpretive keys to improve the understanding of one of the most important events in the industries’ transformation in the current economy, that of digital convergence. Purpose of the paper and methodology. This research work provides an original contribution to the question of how market convergence affects industry evolution. The paper analyzes the convergence process that has influenced the evolution of the tablet sector and the dynamics of entry, exit, innovation and competition over the industry life cycle. From a methodological point of view, a historical-longitudinal study was carried out, which was aimed at examining – supported by a qualitative/quantitative analysis – the sequence of events that, over 30 years, influenced the development of the tablet industry. Findings and implications. From the analysis some interesting findings emerged. Firstly, it was found that the life cycle curve of the converging tablet industry defined on the basis of sales data followed the ‘S-shaped pattern’ empirically detected by product and industry life cycle studies. Secondly, we have verified that the evolution of firm population and the level of product innovation in the tablet industry are consistent with two temporal patterns that characterize the evolutionary model, identified by evolutionary economics and technology management studies. It has also been found that the sectoral convergence process has affected the dynamics of competition in the tablet industry. It emerged, in fact, that the leading companies in introductory stages of the development of the tablet market – which came from the personal computer industry – quickly lost their market position in favor to newcomer firms that came from different converging sectors. The analysis has also made it possible to highlight that tablet market leaders tend to compete with each other in multiple sectors within the scope of a broader convergent mobile digital device market. Therefore, a ‘hybrid competition’ seems to have been affirmed between technological devices – smartphones, notebooks, tablets, smartwatches, e-readers – different in shape, but united by satisfying, in different ways, a need for simplified access on the move to a series of advanced digital functions and services.