Miracle-dz/UniFAR-FTUs huggingface dataset:
New Pantolestids from the Uinta Formation, Utah

ABSTRACT New dental and postcranial specimens of Pantolestes from the Uinta Basin, Utah, are described, and species-level diversity of Pantolestes from the Bridgerian and Uintan North American Land Mammal Ages is assessed. Because few morphological features can be found to distinguish species, we use size as the primary criterion for species membership. We recognize two species from the Bridgerian, P. longicaudus and P. natans. We consider P. elegans a junior synonym of P. longicaudus based on essentially identical size and dental morphology and include P. phocipes within P. natans based on the same criteria. Pantolestes intermedius is problematic, because the only known specimens are postcranial and pantolestids as a group show significant postcranial growth even after dental eruption is complete. However, its extremely reduced size relative to P. natans suggests that it is distinct from this species, and, although larger, it is closer in size to a referred specimen of P. longicaudus. We place all specimens of Uintan Pantolestes within either P. longicaudus or P. natans based on overall similarity in size and morphology. The postcranial remains of Uintan Pantolestes are fragmentary but show little morphological difference from earlier pantolestids. This suggests that Uintan pantolestids maintained an aquatic lifestyle despite the recession of ancient lakes in the continental interior occurring during that time. It is possible that the extreme rarity of Uintan pantolestids compared with earlier relatives is linked to the shrinking of aquatic habitats.
Effect of Spinal Decompression Therapy Compared with Intermittent Mechanical Traction in Lumbosacral Disc Herniation

Objective: To compare the effects of intermittent mechanical traction with spinal decompression therapy (SDT), using the newly introduced device DRX 3000Ⱂ, in patients suffering from low back pain associated with lumbosacral disc herniation documented on MRI. Method: Thirty-five patients with low back pain with or without lower extremity radiating pain were prospectively enrolled in this study. They were all diagnosed with lumbosacral disc herniation according to physical examinations and MRI. Patients over age 60 years or those with previous spinal surgery, spondylolisthesis, severe osteoporosis, rheumatic diseases, hypertension, and other serious medical problems were excluded. Patients were randomly assigned to intermittent mechanical traction group (15 patients) or SDT group (20 patients) and compared visual analog pain scale (VAS) pre- and post-treatment. Results: There was a significant improvement in VAS in SDT group compared to intermittent mechanical traction group. The mean reduction in VAS for intermittent mechanical traction group equaled 1.93±0.83 (from 6.4±1.28 to 4.5±1.22) while the mean reduction in VAS in SDT group equaled 4.35±2.21 (from 6.9±1.86 to 2.6±1.43) (p=0.0006). Conclusion: Spinal decompression therapy can be used as an effective treatment for discogenic low back pain without serious complications. (J Korean Acad Rehab Med 2008; 32: 319-323)
Study of respecting patients rights from nurses point of view employed in Yazd hospitals

رد و يونعم و يعامتجا ،يحور ،يمسج داعبا اب يدوجوم ناــ سنا كمك نودب هــ ك (1) تــ سا يقوقح ياراد يراــ ميب و تملاــ س نارود لبق اهلاــ س . (2) تــ سين نآ بــ سك و تيامح ، عافد هب رداــ ق نارــ گيد اهنآ طقف هك دندرك ىم ركف ناكشزپ صوصخب يتــ شادهب هفرح نانكراك تشونرس نييعت هب زاجم هدوب هاگآ ناسنا يتسردنت و تملاس هب تبسن رد ،ندوب ريذپ بيــ سآ تلع هب ناراميب هجيتن رد ؛(3) دنتــ سه ناراميب رارق ينامرد و يتــ شادهب متــ سيس توق و فعض طاقن و تافلخت ضرعم تاعوضوم هب تبــ سن هعماج يهاگآ شيازفا هزورما اما ؛(4) دــ نتفرگ يم ثعاب تامدخ نيا زا هدافتسا هدنيازف ياه هنيزه و ينامرد و يتــ شادهب زا اهنآ و (2) تــ سا هدــ ش نايضاقتم نايم رد لاعف شبنج كــ ي زورــ ب و تامدخ لماك تيلوئــ سم دنراد راظتنا ينامرد رداك و اه ناتــ سراميب و (3) دنريگب هدهع هب ار دوخ فرط زا هدــ ش هيارا يكــ شزپ ياه تبقارم . (5) دنهد يم ناشن لمعلا سكع ناشتاراظتنا ندــ شن هدروآرب تروص رد . تــ سا اه هاگداد هب مدرم ناوارف ياه تــ ساوخداد و اهاعدا رما نيا هاوگ ظفح تهج رد يتاررقم و نيناوق ميظنت و راميب تيامح هب زاين نياربانب اهنآ ندرك ميهس و ناراميب ندومن هاگآ هك ارچ (1) تــ سا راميب عفانم تعرس ار اهنآ يدوبهب ناــ شقوقح ندرمــ ش مرتحم و يريگ ميمصت رد رد و (3) دــ هاك يم ار ناتــ سراميب رد ندوب يرتــ سب نارود ،هديــ شخب رهش ياهناتسراميب رد لغاش ناراتسرپ هاگديد زا راميب قوقح تياعر يسررب دزي
Clinical study on role of life events in genesis of neurotic disorders and depression

Background: This study was conducted to know about the role of life events in genesis of neurotic disorders and depression in four groups of patients with dissociative disorder, somatisation disorder, generalized anxiety disorder (GAD), and depression. It was conducted in the Department of Psychiatry, Gauhati Medical College and Hospital, Guwahati, Assam, India. Methods and materials: It was a case control study with 100 cases of neurotic disorders and depression (25 cases in each group) attending indoor and outdoor, and diagnosed using research diagnostic criteria of the tenth revision of the International Statistical Classification of Diseases and Related Health Problems (ICD-10). The groups were compared with similar number of matched controls, in respect to number, scoring, and type of life events occurring within one year prior to the onset of illness using the Presumptive Stressful Life Events Scale (PSLES). Variables related to sociodemographic characteristics were also seen between cases and controls. Result and conclusion: Number of life events was significantly higher in depressive and generalized anxiety groups than control group. Total life events scores were significantly higher in depressive and generalized anxiety group than control group. Undesirable events were significantly higher in all groups. Personal events were significantly higher in depressives than control. Events related to interpersonal relation were significantly higher in depressive, dissociative, and GAD groups than control. Bereavement was closely associated with depression and GAD. Events related to health, finance, and education were higher in dissociative group than control. Events related to move were found significantly higher in GAD group than control. Implications of the findings are discussed. Medhi D, Das PD. Clinical study on role of life events in genesis of neurotic disorders and depression. Open J Psychiatry Allied Sci. 2015;6:138-42. doi: 10.5958/2394-2061.2015. 00012.9
Predatory Potential of Spotted Ladybird Beetle, Harmonia octomaculata (Fabricius) (Coccinellidae: Coleoptera) on Lucerne aphid, Acyrthosiphon pisum (Harris) (Aphididae: Hemiptera) under Laboratory Conditions

Coccinellid beetles are important predators of aphids in agricultural crops and have been used as biological control agents against a number of aphid species due to their ability to feed on a wide range of prey and these predatory beetles are voracious in nature and have a rapid numeric response thereby they have wonderful potential for utilization in biological pest control programme of aphids in various agro-ecosystem (Shinde, 2012). Among the various cultivated crops, lucerne, Medicago sativa L. (Family: Medicago) has the highest feeding value as a commonly grown fodder crop. The aphids such as pea aphid, Acyrthiosiphon pisum (Harris), bluegreen aphid, Acyrthosiphon kondoi (Shinjii) and spotted alfalfa aphid, Therioaphis trifolii (Fab.) are severely feeding on lucerne crop and resulted in to 25 per cent of global production losses. The lucerne aphid, A. pisum is large in size compared to other aphids and green in colour with long appendages, usually International Journal of Current Microbiology and Applied Sciences ISSN: 2319-7706 Volume 8 Number 09 (2019) Journal homepage: http://www.ijcmas. com
Modelling and control of hyperglycemia in critical care patients

Critically ill patients are known to experience stress-induced hyperglycemia. Inhibiting the physiological response to increased glycemic levels in these patients are factors such as increased insulin resistance, increased dextrose input, absolute or relative insulin deficiency, and drug therapy. Although hyperglycemia can be a marker for seveIity of illness, it can also worsen outcomes, leading to an increased risk of further complications. Hyperglycemia has been quantified in critically ill patients showing the need for glucose control. The development of a relatively simple system model and the verification of both genenc and patient specific parameters have been successful in control trials and simulations over a range of critically ill patients. Stepwise reduction of blood glucose values by adaptive control was shown to be accurate to within 20 %, and average long-tenn fitting errors are within the measureIllent error of the glucose sensor. A control algorithm capable of tight regulation for a glucose intolerant ICU patient would thus reduce mortality, as well as the burden on medical resources and time with current experience-based control approaches used in most critical care units. Overall, the research presented is a significant step towards fully automated adaptive control of hyperglycaemia in critically ill patients.
MEDITERRANEAN SEA FRY; A SOURCE OF ISOPOD INFESTATION PROBLEM IN EGYPT WITH REFERENCE TO THE EFFECT OF SALINITY AND TEMPERATURE ON THE SURVIVAL OF LIVONECA REDMANII (ISOPODA: CYMOTHOIDAE) JUVENILE STAGES.

Parasitic isopods have received considerable attention as they cause series impacts on their hosts either alone or with other environmental stresses such as water pollution. The present study investigated the infestation status with isopods among the fry collected from the natural sources . Also to demonstrate the effects of different salinity and temperature combination on the survival rates of the identified isopods under the laboratory conditions. In March 2017,a total of 16 thousand mugiliid fry were sampled from The Fry Collection center at Al Behera Governorate ,Egypt and examined for the presence of isopods . Samples were found infested with a rate of 10.6% , the result which practically documented that isopods were introduced into lake Qarun through dumping millions of infected fry from this source without biosecurity procedures. The isolated juvenile isopods were morphologically and molecularly identified as Livoneca redmanii species by using 16S rRNA gene and recorded in the GenBank with accession number: MK584629. The effects of variables of salinity/ temperature combination on the survival% of the identified juveniles showed that the best survival rate(100%) was recorded in salinity 15 -20% at temperature 25⁰C while the lethal combination was in salinity 10, 20,50 and 60% at temperature 35⁰C . Statistical analysis using A-two way ANOVA indicated a significant interaction between the effect of different degree of temperature and variance of salinity% on the survival of L. redmanii juveniles. Analysis of one way ANOVA indicated that the most effective temperature of overall mean temperature affected on survival of juvenile stage was 35 C⁰ while the most effective salinity percentage on survival of Juvenile from overall mean of salinity % was 10%. Results of this study provided applicable procedures which can be recommended as a precaution measures and for eliminating the isopod juvenile stages among the mugiliid fry.
Studying development and experience-dependent plasticity of visual cortex: Using modern approaches, animal models and human post-mortem tissue

When the visual system is confronted with adverse early-life experiences, maladaptive plasticity permits development of poor vision in a disorder called amblyopia. Patch therapy is the common treatment for amblyopia, by which occluding the good eye manipulates residual plasticity to improve acuity in the poor eye. Unfortunately patch therapy does not work for everyone and improvements are often transient. Animal models of amblyopia have highlighted the neurobiology after the initial insult, but little is known about the response to treatment. Since synaptic proteins are the interface between neuronal structure and function, it is imperative that neuroscientists study the amblyopic synaptic proteome to better map intervention strategies in humans. In the first part of this thesis I modernize 3 approaches for examining central visual pathway. First I combine neuroanatomical tracing with modern tissue clearing to examine central visual pathway connectivity. Next, I improved a manual fractionation protocol for enriching synaptic protein expression in cortical tissues. Third, I present a series of analytical techniques for multi-dimensional statistics to interpret protein expression in cortical tissue samples. In the second part of this thesis I used these techniques to examine a set of commonly studied synaptic plasticity mechanisms in a cat model of amblyopia. I identified the neurobiological plasticity phenotype of patch therapy and treatment alternatives. I then examined expression of 23 synaptic and non-neuronal proteins in post-mortem tissue samples from human visual cortex across development to identify neuroplasticity states. These chapters identify options for improved or augmented therapies by identifying the plasticity phenotypes in animal models of amblyopia, and across human development. Together these tools identify potential successes and failures of existing behavioural interventions, such as binocular vision, as well as the causes of suboptimal treatments in human development, such as early periods of protein heterogeneity.
Quality of Life and Prevalence of Chronic Illnesses among Elderly People: A Cross-Sectional Survey

Background & Objectives: Elderly is a stage of human growth and development. In order to improve elderly Quality of life, more attention should be paid on their expectation and needs at this stage. The purpose of this study was to determine Quality of Life and prevalence of chronic illness in elderly people. Methods: This descriptive cross-sectional study was conducted on 200 participants who were cognitively intact. Cluster sampling method was used to select samples and data were collect using Farsi version of Short Form Health Survey (SF36) questionnaire. The data on chronic disease were gathered through interview. Descriptive statistics, t-test, and ANOVA were used for data analysis. Results: Average score for QoL was 57.43±22.80 (ranging from 0 to100). QoL statistically correlated with gender, educational levels, economic status, and health status ( p <0.05). The result of study revealed that 82% of participants suffer at least from one chronic disease. Conclusion: This study showed that different factors affect QoL of elderly people and the majority of them suffer at least from one chronic illness. Therefore, any planning to increase social contribution of elderly population and improve medical and health services; special attention should be paid on these factors.
Functional design of pH-responsive folate-targeted polymer-coated gold nanoparticles for drug delivery and in vivo therapy in breast cancer

Background Curcumin has been widely used owing to its various medicinal properties including antitumor effects. However, its clinical application is limited by its instability, poor solubility and low bioavailability. Folic acid (FA)-functionalized nanoformulations may enhance the sustained release of an anticancer drug (curcumin) by tumor-specific targeting to improve therapeutic benefit. This study aims to design a nanoconjugate (NC) comprised of folate–curcumin-loaded gold–polyvinylpyrrolidone nanoparticles (FA–CurAu-PVP NPs) for targeted delivery in breast cancer model systems. Methods We developed curcumin-loaded FA-functionalized Au-PVP NCs by layer-by-layer assembly. The folic acid–curcumin Au-PVP NCs (FA–CurAu-PVP NCs) were characterized by ultraviolet–visible spectra, Fourier transform infrared spectroscopy, X-ray powder diffraction and thermogravimetric analysis. In vitro anticancer and antimigratory effects of NCs were examined by performing MTT and wound migration assays. The in vivo antitumor efficacy of NCs was investigated using a preclinical breast cancer orthotopic mouse model. Results Curcumin (40 µg/mL) was loaded along with conjugation of folate onto Au-PVP NPs to form FA–CurAu-PVP NCs. The size and charge of the NCs were increased gradually through layer-by-layer assembly and showed 80% release of curcumin at acidic pH. The NC did not show aggregation when incubated with human serum and mimicked an intrinsic peroxidase-like property in the presence of 3,3ʹ,5,5ʹ-tetramethylbenzidine substrate. The MTT data using these NCs showed efficient anticancer activity at lower doses in estrogen/progesterone receptor (ER/PR)-negative cells compared with ER/PR-positive cells. Furthermore, the NCs did not show cytotoxicity at the investigated concentration in human breast epithelial and mouse fibroblast cell lines. They showed inhibitory effects on cell migration and high antitumor efficacy in in vivo analysis. Conclusion These results suggest that folate-based tumor targeting using CurAu-PVP NCs is a promising approach for tumor-specific therapy of breast cancer without harming normal cells.
Variability of Cinnamomum (Lauraceae) Leaf Architecture in Relation to Climatic and Historical Constraints: Implications for Paleoclimatic Studies

Premise of research. Fossil leaves are commonly used as proxies for continental paleoclimate reconstruction. In particular, temperature and precipitation variables are derived from taxon-free methods using only fossil leaf morphology. Although there is a general relationship between leaf form and climate at a global scale, possible differences between and within angiosperm families remain little explored. Methodology. In this article, we analyzed the influence of phylogenetic relatedness and climate on leaf architecture in 30 species of Cinnamomum (Lauraceae). Nineteen morphological features were selected and documented on the basis of digitized herbarium specimens. Repeatability was measured for all traits. Phylogenetic signal was measured using Blomberg’s K. The relationship between morphological variables and climatic variables was investigated using univariate and multivariate statistical approaches. Pivotal results. Our analysis revealed that phylogenetic signal was mainly observed in traits linked to the venation pattern. Size- and shape-related variables are more influenced by climatic parameters than by historical constraints. Cinnamomum leaf morphology is significantly correlated with mean annual temperature and temperature seasonality. Conclusions. Shape and size are representative of convergent temperature-related characters in this genus. Our analysis validates the use of this genus for taxon-free paleoclimatic reconstruction methods relying on such data. The absence of phylogenetic signal in size- and shape-related traits contrasts with earlier studies on distantly related taxa and confirms that historical constraint on leaf morphology is variable among families.
Performance of okra ( Abelmoschus esculentus (l.) moench) cultivars under summer and rainy environments

A number of varieties of Okra are under cultivatio n in West Bengal. However, our main aim was to scree n the available varieties under two seasons, i.e., Su mmer and Rainy to go for a comparative analysis based on the performance of the lines under two growing seasons. On this back ground the investigation was pursued to evaluate the diverse okra lines / varieties for yie ld and it’s related components, estimate variance componen ts, degree of association between yield and yield contributing traits and direct effects of yield com ponents on total fresh yield per plant under both the environments.
RNA/DNA ratio and expression of GHR and IGF-1 hormones: A study on seasonal variation effect on growth characterization of male Oreochromis niloticus

Nile tilapia (Oreochromis niloticus) is considered as one of the most economical and popular aquaculture species. One of the main concerns in tilapia aquaculture, as well as in the wild, is growth, because of its importance for the fish population, stock assessment and their production in aquaculture. Accordingly, this study was initiated to characterize growth on molecular basis. In the same respect, RNA/DNA ratio and GHR-1/IGF-1as growth-related genes are known to be involved in weight gain alterations. To assess the correlation between growth, biochemical and hormonal conditions of fish during summer and winter. Adult male O. niloticus (100 - 250gm) were collected from Bahr Shebeen Canal, for such investigation. The results revealed that the GHR-1 and IGF-1 mRNA were directly proportional to age, length and weight. However, they were up regulated in summer than in winter. However, RNA/DNA ratio gave an observable positive correlation with age and length only with higher values in winter. In conclusion, this study supports the use of GHR-1/IGF-1as reliable indices of growth and condition of O. niloticus in their natural habitat in addition to RNA/DNA ratio assessment.
RELATIONSHIP AMONG CREATIVELY, JOB SATISFACTION AND MENTAL HEALTH IN FEMALE NURSES

Background & Aim : Creativity of the personnel of organizations is one of the major factors in their advancement. This study aims to determine the relationship between creatively, job satisfaction and mental health in female nurses. Material & Methods : It was a descriptive correlational study. Among Bushehr ’ s hospitals, three were selected by random cluster sampling method and among the nurses working in these hospitals, 60 married and unmarried female nurses of CCU and ICU were randomly selected and responded to the job satisfaction, general health questionnaires and creativity questionnaire of Abedi. The data were analyzed by Pearson's correlation coefficients for subscales and t tests using SPSS-PC (v.16). Results : There was a significant negative correlation between anxiety and creativity development . Also there was a significant negative correlation between depressive symptoms and satisfaction with the nature of the work and there was a significant negative correlation between symptoms of social dysfunction and satisfaction with pay, satisfaction of the nature of work and job satisfaction total score (p ≤ 0/05). Also the Mean difference between married and unmarried female nurses in physical signs and symptoms of anxiety of mental health and initiative and flexibility of creativity was significant (p<0.05) but findings did not show any differences in job satisfaction in married and unmarried female nurses. Conclusion : According to the findings, promotion of the nurses’ levels of function for protection and promotion of their mental health by providing them with training and skills related to creativity and creative strategies and also strategies to increase their job satisfaction is recommended.