Miracle-dz/UniFAR-FTUs huggingface dataset:
Multivariate classification provides a neural signature of Tourette disorder

Abstract Background Tourette disorder (TD), hallmarks of which are motor and vocal tics, has been related to functional abnormalities in large-scale brain networks. Using a fully data driven approach in a prospective, case–control study, we tested the hypothesis that functional connectivity of these networks carries a neural signature of TD. Our aim was to investigate (i) the brain networks that distinguish adult patients with TD from controls, and (ii) the effects of antipsychotic medication on these networks. Methods Using a multivariate analysis based on support vector machine (SVM), we developed a predictive model of resting state functional connectivity in 48 patients and 51 controls, and identified brain networks that were most affected by disease and pharmacological treatments. We also performed standard univariate analyses to identify differences in specific connections across groups. Results SVM was able to identify TD with 67% accuracy (p = 0.004), based on the connectivity in widespread networks involving the striatum, fronto-parietal cortical areas and the cerebellum. Medicated and unmedicated patients were discriminated with 69% accuracy (p = 0.019), based on the connectivity among striatum, insular and cerebellar networks. Univariate approaches revealed differences in functional connectivity within the striatum in patients v. controls, and between the caudate and insular cortex in medicated v. unmedicated TD. Conclusions SVM was able to identify a neuronal network that distinguishes patients with TD from control, as well as medicated and unmedicated patients with TD, holding a promise to identify imaging-based biomarkers of TD for clinical use and evaluation of the effects of treatment.
A Small Signal Equivalent Circuit Model for Resonant Tunnelling Diode

We report a resonant tunneling diode (RTD) small signal equivalent circuit model consisting of quantum capacitance and quantum inductance. The model is verified through the actual InAs/In0.53Ga0. 47As/AlAs RTD fabricated on an InP substrate. Model parameters are extracted by fitting the equivalent circuit model with ac measurement data in three different regions of RTD current-voltage (I-V) characteristics. The electron lifetime, representing the average time that the carriers remain in the quasibound states during the tunneling process, is also calculated to be 2.09 ps.
Genotoxicity and Cytotoxicity Induced in Zygophyllum fabago by Low Pb Doses Depends on the Population’s Redox Plasticity

Lead (Pb) soil contamination remains a major ecological challenge. Zygophyllum fabago is a candidate for the Pb phytostabilisation of mining tailings; nevertheless, the cytogenotoxic effects of low doses of Pb on this species are still unknown. Therefore, Z. fabago seeds collected from non-mining (NM) and mining (M) areas were exposed to 0, 5 and 20 µM Pb for four weeks, after which seedling growth, Pb cytogenotoxic effects and redox status were analyzed. The data revealed that Pb did not affect seedling growth in M populations, in contrast to the NM population. Cell cycle progression delay/arrest was detected in both NM and M seedlings, mostly in the roots. DNA damage (DNAd) was induced by Pb, particularly in NM seedlings. In contrast, M populations, which showed a higher Pb content, exhibited lower levels of DNAd and protein oxidation, together with higher levels of antioxidants. Upon Pb exposure, reduced glutathione (GSH) and non-protein thiols were upregulated in shoots and were unaffected/decreased in roots from the NM population, whereas M populations maintained higher levels of flavanols and hydroxycinnamic acids in shoots and triggered GSH in roots and shoots. These differential organ-specific mechanisms seem to be a competitive strategy that allows M populations to overcome Pb toxicity, contrarily to NM, thus stressing the importance of seed provenance in phytostabilisation programs.
The role of QMS in the relationship between innovation climate and performance

The emergence of new global competitors, the convergence of high-technology industries and the increasing speed and cost of technological development promises an increasingly uncertain environment for organisations, making adaptation to changes in the environment a central theme in the study of the organisation for both organisation theory and strategic management. This study thus seeks principally to verify that, while innovation and quality management (QM) alone do not possess the qualities required to provide organisations with sustainable competitive advantages, the bundle of innovation and QM together with other resources and competencies will allow organisations to obtain a competitive advantage and adapt to their environment. The results show that the factors determining innovation – such as resistance to change, cohesion and workload pressures – have repercussions for the firms’ capacity to adapt to their environmentand that a QM context facilitates this adaptation. Finally, we can conclude that a climate of support for innovation is positively related to the organisation’s performance.
Depression, Anxiety and Well-Being Among HIV-Positive Adolescents in Lagos, Nigeria

Objective: To determine the prevalence and correlates of depression and anxiety among HIVpositive adolescents attending the HIV-clinic at Lagos state University Teaching Hospital, Nigeria. Methods: This was a cross-sectional study of 155 HIV-positive adolescents (between the ages of 10 to 18 years) who were recruited using total sampling method at a Pediatric HIV/AIDS OutPatient clinic in Lagos, Nigeria. Questionnaires used were: MINI-KID (MINI International Neuropsychiatric Inventory (for children and adolescents), MINI-KID Screen, Jacoby Stigma Scale, Pediatric Quality of Life Inventory, Morisky Medication Adherence Scale and Oslo Social Support Scale. All these questionnaires have been demonstrated to have good internal consistency (>0.70) and validity. Results The prevalence of depression and anxiety were 23.9% and 12.9% respectively. Correlates of depression were stigma (OR=1.43, CI=1.22-1.69), bullying (OR=0.29, CI=0.13-0.63), poor perceived social support (OR=2.41, CI= 1.15-5.54), total quality of life (OR=0.94, CI=0.920.97), school functioning (OR=0.94, CI=0.91-0.97), emotional functioning (OR=0.96, CI=0.940.98). Correlates of anxiety include, viral load (OR=0.55, CI=0.33-0.93), stigma (OR=0.69, 0.55-0.85), anti-retroviral medication adherence (OR=0.59, CI=0.38-0.90), awareness of HIV/AIDS diagnosis (OR=0.23, CI=0.06-0.85), emotional functioning (OR=1.13, CI=1.071.18), physical functioning (OR=1.05, 1.02-1.08), social functioning (OR=1.23, CI= 1.21-1.26), total quality of life (OR=1.05, 1.02-1.08), age (OR=0.81, CI=0.66-0.89) and poor perceived social support (OR=1.23, CI=1.11-1.99). International Journal of Medical Science and Health Research Vol. 5, No. 05; 2021
Analysis of a “Simple” Medical Device

EDICAL D EVICES A RE D ESIGNED T O improve the health of an individual. Advances in the technology of medical devices may enable patients to take an active role in maintaining their own health. One example is the hand-held, battery-operated meter that patients with diabetes can use to check their blood glucose levels. Through self-monitoring, diabetes patients can determine their blood sugar levels and adjust diet, insulin, or exercise to effectively manage their diabetes. The advent of self-care, unfortunately, has some negative consequences as well. The patient must take primary responsibility for monitoring blood glucose levels without assistance from a health care professional. As a result, there may be an increase in the occurrence of errors in the use of blood glucose meters (see Laux, 1994, for monitoring difficulties when meters are unavailable). These errors can have serious consequences for the short- and long-term health of the individual, particularly because treatment is often determined from glucose level readings. Diabetes can lead to many complications if not properly treated, including high blood pressure, heart or kidney disease, vision problems or blindness, complications in pregnancy, and death. Blood glucose meters represent a class of home health care technologies in which the tasks are sequential in nature – that is, each step is reliant on the success of the previous step. The system also provides very little feedback about the accuracy of performance, and the consequences of errors are high. Other devices in this class would include blood pressure monitors, heart rate monitors, oxygen tanks, and infusion pumps. In this article, we demonstrate how human factors/ergonomics tools can be applied to medical devices in general, and blood glucose meters in particular. We focus on blood glucose meters because of their widespread use and availability, but our approach and findings can be gen
Nuclear Matter in 1+1 Dimensions

I review the solution of QCD in two spacetime dimensions. Following the analysis of Baluni, for a single flavor the model can be analyzed using Abelian bosonization. The theory can be analyzed in strong coupling, when the quarks are much lighter than the gauge coupling. In this limit, the theory is given by a Luttinger liquid.
Yield-Related QTL Clusters and the Potential Candidate Genes in Two Wheat DH Populations

In the present study, four large-scale field trials using two doubled haploid wheat populations were conducted in different environments for two years. Grain protein content (GPC) and 21 other yield-related traits were investigated. A total of 227 QTL were mapped on 18 chromosomes, which formed 35 QTL clusters. The potential candidate genes underlying the QTL clusters were suggested. Furthermore, adding to the significant correlations between yield and its related traits, correlation variations were clearly shown within the QTL clusters. The QTL clusters with consistently positive correlations were suggested to be directly utilized in wheat breeding, including 1B.2, 2A.2, 2B (4.9–16.5 Mb), 2B.3, 3B (68.9–214.5 Mb), 4A.2, 4B.2, 4D, 5A.1, 5A.2, 5B.1, and 5D. The QTL clusters with negative alignments between traits may also have potential value for yield or GPC improvement in specific environments, including 1A.1, 2B.1, 1B.3, 5A.3, 5B.2 (612.1–613.6 Mb), 7A.1, 7A.2, 7B.1, and 7B.2. One GPC QTL (5B.2: 671.3–672.9 Mb) contributed by cultivar Spitfire was positively associated with nitrogen use efficiency or grain protein yield and is highly recommended for breeding use. Another GPC QTL without negatively pleiotropic effects on 2A (50.0–56.3 Mb), 2D, 4D, and 6B is suggested for quality wheat breeding.
A New Biflavanone from Ochna Lanceolata

A new biflavonoid, ent-ruixianglangdusu B (1), together with three known compounds, namely ochnaflavone (2), (-)-epicatechin (3) and kaempferol-3-O-α-L-rhamnopyranoside (4) were isolated from the leaves of Ochna lanceolata. The structures of these compounds were determined by means of spectral and chemical studies.
Steady turning of motorcycles

Abstract When driving along a circular path, the rider controls a motorcycle mainly by the steering torque. If the steering torque is low and the vehicle is moderately over-steering, a good handling feeling is perceived by the rider. In this paper, non-linear steady turning results are analysed over a wide range of forward speeds and lateral accelerations, and different ‘driving zones’ are identified by considering the steering torque transition speeds and steering angle critical speed. A parametric linear model of steady turning, concerning both the steering torque and the steering angle, is developed and simple parametric expressions of transition speeds and the critical speed are obtained. Steady turning tests involving different motorcycles are presented, the transition speeds and critical speed are found by linear fitting, and the characteristics of the different driving zones are investigated. The primary purpose is to determine the conditions at which the operational safety and handling of the vehicle do not impose severe demands on rider skill for control and adequate path-following properties, i.e. to identify a ‘preferable driving zone’.
On the assessment of harmonic pollution [of power systems]

This paper analyses the interactions between the incremental changes of current harmonic phasors injected by a power system NL (nonlinear load) and the resulting variations of harmonic voltages and powers. It proves that it is not always possible, following simple measurements of individual harmonic powers, to decide if a certain harmonic current is harmful or useful. It is suggested that the NL "distortion" be evaluated with the help of a quantity called non60 Hz (nonfundamental) apparent power. >
Kemahiran Pengurusan Masa Pelajar Universiti Tempatan: Status Dan Hubungannya Dengan Pencapaian

Kemahiran pengurusan masa merupakan salah satu kemahiran belajar yang penting untuk dikuasai oleh pelajar bagi membantu mereka mencapai kejayaan cemerlang semasa menuntut di universiti. Walau bagaimanapun, kajian yang menyeluruh tentang sejauh mana kemahiran ini dimiliki oleh pelajar institusi pengajian tinggi tempatan dan kesannya terhadap prestasi mereka masih belum banyak dilakukan. Justeru, kertas kerja ini cuba mengupas isu tersebut berdasarkan kajian ke atas 3025 orang pelajar dari tujuh buah universiti awam dan dua buah universiti swasta yang mengikuti pengajian dalam pelbagai bidang. Data dikumpul dengan menggunakan satu set soal selidik dan ia dianalisis secara deskriptif serta menggunakan ujian–t, ANOVA dan korelasi Pearson. Dapatan kajian mendapati secara umum, kemahiran pengurusan masa dalam kalangan responden kajian adalah sederhana dan kemahiran ini berbeza secara signifikan antara jantina, tahun pengajian dan bidang pengajian. Kajian ini juga mendapati hubungan yang signifikan antara pengurusan masa dengan prestasi atau purata nilai gred kumulatif (r = .127, p < .01). Kata kunci: Kemahiran pengurusan masa; kemahiran belajar; pembelajaran di peringkat pengajian tinggi Time management skill is one of the most important study skills that need to be acquired by students in assuring excellent achievement in the university. However, indepth studies on the extent this skill has been acquired by students in local higher education institutions and its impact on students’ performance has not been fully explored. Thus, this paper discusses this issue based on a study on 3025 students from seven public and two private universities across various study programmes. Data was collected using a set of questionnaire and analyzed descriptively using t–test, ANOVA and Pearson correlation. Findings of this study found that generally, time management skill of the respondents was generately at moderate and significant differences were established between gender, year of study and fields of study. This study also found significant relationship between time management and performance or cummulative grade point average (r = .127, p < .01). Key words: Time management skills; learning skills; learning at higher institutions
Seed biopriming with indigenous endophytic bacteria isolated from Wakatobi rocky soil to promote the growth of onion (Allium ascalonicum L.)

The realization of sustainable agriculture requires continuous research which can reduce the use of chemical fertilizers. This research was carry out to obtain the potential indigenous endophytic bacteria isolated from onion planted on rock soil of Wakatobi district in Southeast Sulawesi. The study conducted using a completely randomized design (CRD) consisting of 9 isolates. Germination was recorded daily until 14 days. At the same time, isolates evaluated for their ability to solubilize phosphate, fix N and synthesize IAA. Results showed that the seed treatments using endophytic bacteria significantly increased viability onion seeds, in term of germination increases in germination percentage. Almost all endophytic bacteria isolate tested were able to solubilize phosphate, fix N and synthesize IAA. From this study, Ke03 isolates showed the best performance and were able to increase germination percentage, root length and number of onion roots reaching 145%, 46% and 78% respectively, as compared to controls. The ability of Ke03 isolates to increase onion germination correlated with the ability of this isolate to synthesize IAA (80.33 ppm). Further research is needed to evaluate whether this isolate is effective in increasing the growth and yield of onions in the field.
Radiographic Detection of Rib Fractures: A Restraint-Based Study of Occupants in Car Crashes

Twenty-nine human cadavers were subjected to frontal impacts using two restraint conditions:: torso belt-only (14 tests), and torso belt-and-airbag (15 tests). Five radiologists independently evaluated post-test chest films, and their results were compared with detailed necropsy results. The radiologists' ability to identify rib fractures was influenced by the restraint system, rib number, aspect (right or left), circumferential location of the fracture, and the number of fractures on the rib. The probability of fracture detection (sensitivity) was significantly higher for the torso belt-only group (0.44) than for the belt-and-airbag group (0.24). Knowledge of fracture locations increased the overall (both restraint groups) sensitivity from 0.40 to 0.49. It is concluded that the sensitivity is dependent on the restraint system used. Since rib fractures are the injuries most commonly used to describe AIS 2+ thoracic injury severity, this dependence may bias field data-based comparative studies of restraint system effectiveness.
Development of an Improved Methodology for Predicting Airblast Pressure Relief on a Directly Loaded Wall

The interaction of an airblast wave with a structure, and the blast wave propagation around and over the structure is of significant importance. In order to protect a structure from the airblast produced by such explosive threats as terrorist bombs, a facility designer must possess an adequate knowledge of the expected blast wave loading. Of greatest importance are pressures and impulses on the directly loaded face of the structure, since it is typically subjected to the highest (reflected) pressures. It has long been recognized that reflected pressure time histories can be strongly influenced by pressure relief from the free edges of the loaded wall. The relief wave can significantly reduce the magnitude of the late-time portion of the positive reflected pressure phase, resulting in a substantial decrease in the peak impulse load. Most current predictive methodologies attempt to account for the relief wave and its effect on impulse. Unfortunately, these methods tend to be rather inaccurate because the exact manner in which the relief wave is manifested is not accurately defined. The US Army Engineer Research and Development Center has developed an improved methodology to predict the effect of pressure relief. This paper presents the basis for the methodology and its practical application.
A micromachined vibrating gyroscope

Abstract A vibrating microgyroscope with a thin polysilicon resonator fabricated by silicon surface micromachining is described. The 400 μm × 800 μm resonator is driven in a lateral direction by electrostatic force, and the angular rate is detected as the capacitance change between the resonator and its substrate. Mechanical Q -factors for the driving mode and the detecting mode of the polysilicon resonator are 2800 and 16 000, respectively, at pressures below 0.1 Pa. Methods are presented for modifying the difference between the resonance frequencies of the driving and detecting modes. The test device shows a noise-equivalent rate of 2° s −1 .
Two Nucleoporin 98 homologous genes jointly participate in the regulation of starch degradation to enhance growth in Arabidopsis

Background: Starch is synthesized during the day for temporary storage in leaves and then degraded during the subsequent night to support plant growth and development. Impairment of starch degradation leads to stunted growth, even senescence and death. The nuclear pore complex is involved in many cellular processes, but its relationship with starch degradation is unclear until now. We previously identified two Nucleoporin98 ( Nup98 ) genes ( Nup98a and Nup98b ) redundantly regulated flowering through CONSTANS ( CO ) independent pathway. in Arabidopsis thaliana. The nup98a nup98b double mutant also showed severe senescence phenotypes. Results: We found that Nucleoporin 98 ( Nup98 ) participated in the regulation of sugar metabolism in leaves and in turn is involved in senescence regulation in Arabidopsis . We show that Nup98a and Nup98b redundantly function in the different steps of starch degradation, the nup98a nup98b double mutant accumulates more starch than wild type and has a severe early senescence phenotype compared to wild type. The expression of marker genes related to starch degradation was impaired in the nup98a nup98b double mutant, and indicator genes of carbon starvation and senescence expressed earlier in the nup98a nup98b double mutant than that in wild type plants, suggesting abnormality of energy metabolism was the cause of senescence of the nup98a nup98b double mutant. Addition of sucrose to the growth medium can rescue early senescence phenotype of the nup98a nup98b mutant. Conclusions: Our results provided a line of evidence on a novel role of the nuclear pore complex in energy metabolism related to growth and development, whereas Nup98 functioned in starch degradation conferring growth regulation in Arabidopsis .
Measuring Performance in Public and Nonprofit Organizations

Tables, Figures, and Exhibits. Preface. The Author. Part 1: The Management Framework for Performance Measurement. 1. Introduction to Performance Measurement. 2. Developing Effective Performance Measurement Systems. Part 2: Methodological Elements of Performance Measurement. 3. Identifying Real Outcomes and Other Performance Measures. 4. Clarifying Program Goals and Objectives. 5. Defining Performance Indicators. 6. Analyzing Performance Data. 7. Reporting Performance Data. 8. Processing Performance Data. Part 3: Strategic Applications of Performance Measurement. 9. Using Performance Measures to Support Strategic Planning and Management. 10. Incorporating Performance Measures into the Budgeting Process. 11. Supporting Performance Management Systems. 12. Improving Quality, Productivity, and Customer Service. 13. Using Comparative Measures to Benchmark Performance. Part 4: The Process Side of Performance Measurement. 14. Implementing Effective Measurement Systems. References. Index.
Shallow-water Sponges from a High-sedimentation Estuarine Bay (Brunei, Northwest Borneo, Southeast Asia)

Tropical estuaries are important habitats for invertebrates including sponges, a group of marine organisms that fulfill significant ecological roles and provide ecosystem services. Here, we describe the sponge fauna from Pulau Bedukang, a small island in a turbid, variable salinity, acidified and eutrophic estuarine bay (Brunei Darussalam, northwest Borneo). We present records for 14 morphological species (OTUs). Six of these species belong to the Haplosclerida, an order of shallow-water sponges that usually tolerate more variable and extreme physical conditions. Our baseline data contribute to the regional biogeography of sponges and present a reference source for ecological studies on marine animals inhabiting variable estuarine environments. This is the first known record of sponges from the northwest Bornean region of the South China Sea that are not associated with a coral ecosystem; other studies have concerned Singapore, peninsular Malaysia, Thailand, Cambodia, Vietnam, southern China, and Taiwan.