Miracle-dz/UniFAR-FTUs huggingface dataset:
The mitochondrial Ca uniporter: regulation by auxiliary subunits and signal transduction pathways

Bong Sook Jhun,* Jyotsna Mishra,* Sarah Monaco, Deming Fu, Wenmin Jiang, Shey-Shing Sheu, and Jin O-Uchi Cardiovascular Research Center, Department of Medicine, Rhode Island Hospital, Warren Alpert Medical School of Brown University, Providence, Rhode Island; and Center for Translational Medicine, Department of Medicine, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, Pennsylvania
365-xxx Tourism 2020 04ENG.indd

Airbnb in Ecuador is a platform off ering since 2008 a new lodging concept that best can be described as a sharing economy model through the rental of private rooms and apartments. Th e article provides an overview of Airbnb's activities in Ecuador, more in particular in 22 cities, respectively the capitals of 22 provinces, using the 16 metrics available on the platform of AirDNA. Factor analysis was applied to reduce the number of variables to three main surrogate variables (lodging typology, prices and rates, market metrics) that characterizes Airbnb and retains the original factor variability. Additionally, based on the occupation frequency of Airbnb's rental places the cluster analysis permitted to group the cities in which Airbnb is active on the basis of the following indicators: amazon destinations, traditions, sun and beach, nature culture and events, and the country's capital. Th e research provided a clear image of Airbnb's approach and impact on the formal accommodation sector, which ultimately will enable the sector to come up with innovative products to compete more effi ciently Airbnb's market range.
BASKETBALL SMALL-SIDED GAMES: EFFECTS OF VARYING FORMATS AND USING SUCCESSIVE BOUTS

: This study compared athletes’ rate of perceived exertion (RPE) and the number of their technical-tactical actions in small-sided basketball games (SSG) played within the same relative area with adjusted bout durations in (a) varied game formats; and (b) in two successive bouts of different formats. Ten young female basketball players (14.3±1.3 years) played two bouts of five small-sided game (SSG) formats (1x1, 2x2, 3x3, 4x4, and 5x5). The number of technical-tactical actions per player per minute decreased from the smaller to the larger SSG format, and players’ RPE tended to be higher in larger compared to smaller formats. We concluded that the smaller basketball SSG formats increased players’ participation. In addition, adjustments of the relative playing area and bout duration seemed to decrease players’ effort. The use of two SSG bouts did impact the number of technical-tactical actions and RPE.
Predicting Fiscal Crises: A Machine Learning Approach, WP/21/150, May 2021

In this paper I assess the ability of econometric and machine learning techniques to predict fiscal crises out of sample. I show that the econometric approaches used in many policy applications cannot outperform a simple heuristic rule of thumb. Machine learning techniques (elastic net, random forest, gradient boosted trees) deliver significant improvements in accuracy. Performance of machine learning techniques improves further, particularly for developing countries, when I expand the set of potential predictors and make use of algorithmic selection techniques instead of relying on a small set of variables deemed important by the literature. There is considerable agreement across learning algorithms in the set of selected predictors: Results confirm the importance of external sector stock and flow variables found in the literature but also point to demographics and the quality of governance as important predictors of fiscal crises. Fiscal variables appear to have less predictive value, and public debt matters only to the extent that it is owed to external creditors. JEL Classification Numbers: C53, F34, F37, H63
Subsistence Strategies and Craft Production at the Ramesside Fort of Zawiyet Umm el-Rakham

8 Acknowledgements . 9 List of Tables . 10 List of Plates and Figures . 12 Chapter 1: Introduction 1.1. Aims and Data . 21 1.2. Data Recording Methodologies . 25 1.3. Craft Production Systems . 26 Chapter 2: Archaeological and Scholarly Context 2.1. Zawiyet Umm el-Rakham: Excavations and Previous Research. 28 2.2. Site Overview . 33 2.2.1. “mnnw-forts upon the foreign land of Tjemeh” . 35 2.2.2. The Temple and Chapels . 37 2.2.3. Magazines . 39 2.2. 4. Nebre Chapel . 41 2.2. 5. Area N . 41 2.2. 6. The South Building (Area S) . 45 2.2. 7. Granaries H.1-H.3 . 45 2.2. 8. The Huts G1-G8 (Area G) . 46 2.2. 9. Population Composition. 47 2.3. Egypto-Libyan Relations to the early Ramesside Period . 51 Chapter 3: Archaeological Context . 55 3.
University of Alberta Lowering of High Vowels by French Immersion Students in Canada by

While much research has been dedicated to studying the speech of French immersion students, relatively little is known about their sociolinguistic competence, particularly in the area of phonetics. This study aims to determine the extent to which a group of French immersion students in Ontario, Canada display the native Canadian French phenomenon of lowering the high vowel /i/ to its lax allophone /ɪ/ in the obligatory context of a stressed syllable closed by any consonant other than /v, z, ʒ/ or /ʀ/. Results indicate that the majority of the students do not employ the lax vowel, and those students who demonstrate some degree of vowel lowering apply the rule inconsistently. No strong correlation between social or linguistic factors is apparent in the application of the rule, suggesting that more explicit teaching of this phenomenon is necessary in order to make students aware of these kinds of native Canadian French speaker
Web-based instruction for adult learners : an asynchronous delivery model for formal lifelong learning

Web-based Instruction (WBI) is becoming a favored teaching and learning option in higher education. Unfortunately, the effects of WBI on success, perception and gender have not been clearly demonstrated or sufficiently addressed, especially for adult learners who are engaged in the formal lifelong learning via the popular asynchronous WBI (A-WBI). This paper attempts to address the following objectives: (i) to propose a framework for A-WBI to deliver lessons to adult learners who are enrolled in formal lifelong learning; (ii) to implement the proposed framework; (iii) to explore adult learner perceptions of A-WBI and of how gender influences their perception; (iv) to explore the influence of A-WBI on the adult learner summative assessment (final examination component); and (v) o analyze the relationship between adult learner interaction with A-WBI and their final examination marks. Objectives (i) and (ii) are achieved by using the design and implementation approach while objectives (iii), (iv) and (v) are achieved by an interpretive case study methodology approach. The findings indicate: (i) moderate learner responses for the use of A-WBI when studying have led to poor performance in the summative assessment among adult learners; (ii) female learners are the high-risk group in A-WBI; and (iii) quality interaction in the A-WBI discussion forum has a strong relationship with learner final examination scores. The paper concludes with discussions on the findings and recommendations. (Abstract by author)
Quantifying Recent Upsurge in Covid-19 Incidence and Related Fatalities: An Implication of Delayed Response or State of Delivery Health Care System?

Study Aim: To validate the recent upsurge in COVID-19 incidence and related fatalities in a retrospective to the state of the healthcare delivery system and delayed in response to the pandemic in Nigeria. Methods: The quantitative cross-sectional times series method was adopted. COVID-19 Data for Nigeria were extracted for reported cases and fatalities arising from COVID-19 complications from the WHO COVID-19 situational data bank between March 15 and July 15, 2020. The incidence and fatality growth rates were generated at intervals for four months. Data were analyzed with the Stata version 15. Results: Findings showed that the recent upsurge in COVID-19 accounted for 99.2%, 98.9%, 98.5%, 99.8%, 99.2%, 99.8%, and 97.3% complications that led to the death of infected patients in the Northcentral, Northeast, Northwest, Southeast, Southsouth. Southwest and the FCT. The results showed that there was a strong uphill linear (r = 0.991) and a significant association between COVID-19 incidence and fatalities arising from COVID19 complications in Nigeria (ß = 0.022; t = 30.2; p<0.001). Conclusion: The study concluded that the recent upsurge in COVID-19 incidence and fatalities arising from COVID-19 complications could be attributed to delayed response and the poor state of the health delivery system in Nigeria.
The Yeast Mitochondrial Citrate Transport Protein PROBING THE SECONDARY STRUCTURE OF TRANSMEMBRANE DOMAIN IV AND IDENTIFICATION OF RESIDUES THAT LIKELY COMPRISE A PORTION OF THE CITRATE TRANSLOCATION PATHWAY*

The mitochondrial citrate transport protein (CTP) has been investigated by replacing 22 consecutive residues within transmembrane domain IV, one at a time, with cysteine. A cysteine-less CTP retaining wild-type functional properties served as the starting template. The single Cys CTP variants were overexpressed in Escherichia coli, isolated, and functionally reconstituted in a liposomal system. The accessibility of each single Cys mutant to three methanethiosulfonate reagents was evaluated by determining the pseudo first order rate constants for inhibition of CTP function. These rate constants varied by seven orders of magnitude. With three independent data sets we observed peaks and troughs in the rate constant data at identical amino acid positions and a periodicity of four was observed from residues 177–193. Based on the pattern of accessibility we conclude that residues 177–193 exist as an a-helix. Furthermore, a water-accessible face of the helix has been defined consisting of Pro-177, Val-178, Arg-181, Gln-182, Asn-185, Gln-186, Arg-189, Leu-190, and Tyr-193, and a water-inaccessible face has been delineated consisting of Ser-179, Met-180, Ala-183, Ala-184, Ala-187, Val-188, Gly-191, and Ser-192. We infer that the water-accessible face comprises a portion of the substrate translocation pathway through the CTP, whereas the water-inaccessible surface faces the lipid bilayer.
A imagem do Brasil na imprensa alemã antes da crise político-econômica 1

This paper aims at investigating the image of Brazil produced by the German press from 2000 to 2014, employing quantitative content analysis based on a sample of 742 news articles. The study comprises at first the two main leading quality newspapers – the Süddeutsche Zeitung (SZ) and the Frankfurter Allgemeine Zeitung (FAZ) – and additionally the alternative tageszeitung (taz) from Berlin. Moreover, one included the most relevant German political magazine – Der Spiegel. Results demonstrated a different pattern of foreign reporting from the one discussed almost forty
Vectorial Acylation in Saccharomyces cerevisiae Fat1p AND FATTY ACYL-CoA SYNTHETASE ARE INTERACTING COMPONENTS OF A FATTY ACID IMPORT COMPLEX*

In Saccharomyces cerevisiae Fat1p and fatty acyl-CoA synthetase (FACS) are hypothesized to couple import and activation of exogenous fatty acids by a process called vectorial acylation. Molecular genetic and biochemical studies were used to define further the functional and physical interactions between these proteins. Multicopy extragenic suppressors were selected in strains carrying deletions in FAA1 and FAA4 or FAA1 and FAT1. Each strain is unable to grow under synthetic lethal conditions when exogenous long-chain fatty acids are required, and neither strain accumulates the fluorescent long-chain fatty acid C 1 -BODIPY-C 12 indicating a fatty acid transport defect. By using these phenotypes as selective screens, plasmids were identified encoding FAA1 , FAT1 , and FAA4 in the faa1 (cid:1) faa4 (cid:1) strain and encoding FAA1 and FAT1 in the faa1 (cid:1) fat1 (cid:1) strain. Multicopy FAA4 could not suppress the growth defect in the faa1 (cid:1) fat1 (cid:1) strain indicating some essential functions of Fat1p cannot be per- formed by Faa4p. Chromosomally encoded FAA1 and FAT1 are not able to suppress the growth deficiencies of the fat1 (cid:1) faa1 (cid:1) and faa1 (cid:1) faa4 (cid:1) strains, respectively, indicating Faa1p and Fat1p play distinct roles in the fatty acid import process. When expressed from a 2 sa-line (cid:1) on laser oil-immersion objective ensure
Availability and Accessibility of Toys as Determinants of Teaching Effectiveness among Preprimary School Teachers in Uyo Senatorial District of Akwa Ibom State

This paper studied the availability and assessibility of toys as determinants of teaching effectiveness of teachers among pre-primary school teachers in Uyo senatorial district. Two research questions and two hypotheses were formulated as a guide to this study. Expost facto research design was used in carrying out the study. A sample size of 240 pre-primary school pupils was selected using random sampling technique for the study. The researcher developed questionnaire titled “availability and accessibility of toys and teaching effectiveness questionnaire(AATTEQ)” was used to collect data. Data generated were analysed using t-test and pearson product moment correlation coefficient (PPMC). Findings of the study revealed that toys are available and accessed by teachers for use in schools. Teachers who accessed available toys were found to be more effective in teaching than teachers who do not.
FUNCTIONAL PROPERTIES OF SOME VARIETIES OF NEW RICE FOR AFRICA (NERICA) RELEVANT TO ITS PROCESSING FUNKCINALNA SVOJSTVA NOVIH SORTI PIRINČA U AFRICI (NERICA) RELEVANTNIH ZA NJEGOVU PRERADU

Flour from rice can be applicable to several types of food or be used directly as a food substitute, and this can have an impact on the final quality of the product. This aimed to determine the functional properties of some selected NERICA varieties, namely, FARO 44, FARO 52, FARO 57, FARO 60 and FARO 61. Results obtained showed that the functional properties, such as the water absorption capacity (WAC), swelling power, water solubility index (WSI), bulk density, oil absorption capacity (OAC), and the foaming capacity, ranged from 251.74 to 298.51 (%); 7.42 to 8.41 (g/g); 10.01 to 12.27 (%); 0.92 to 1.00 (%); 0.45 to 1.36 (%); and 7.29 to 11.76 (%) respectively. All recorded samples were significantly different (p < 0.05). FARO 61 recorded the highest point of 298.51 (%), and 1.36 (%), in WAC and OAC respectively. While FARO 57 recorded the highest swelling power of 8.41 (g/g). These determined results of the functional properties of NERICA flour samples will be useful in determining their suitability in food and other relevant industries because the flour samples showed a high-quality range of functional properties that make them favourable for such activities.
Determination of the Body Condition Score and Its Relationship with Milk Yield in Turkish Holstein Cows

It is quite important to keep the condition of cows under surveillance due to conduct of nutritional programs in dairy herds as well as genetic relations with other traits. This study was conducted to estimate the heritability of body condition score (BCS) and genetic correlation with milk yield of Holstein cows. Also, the effects of herd, lactation period and calving age on BCS were investigated. For this aim, body conditions of 1001 cows were scored using the scale of 1-9. The average BCS was determined as 5.52±0.04 and its average was ranged from 4.54 to 6.58 at different periods of lactation. Results showed that body conditions were affected by the lactation period significantly (P<0.01), while the effects of herd and calving age on it were not statistically significant. Heritability estimate of BCS was 0.20±0.16 while the genetic correlation of BCS with milk yield was moderately negative (-0.41±0.17) indicating that high-producing cows tend to be leaner. Although with high standard errors, these results indicates that BCS is heritable at low-moderate level and can result in a progress in both traits by defining an appropriate index.
1 Uncertainty , Perception and the Internet

Macroeconomic uncertainty consists of three components: the unobservable, the heterogeneous and the “uncertain”. We are unaware of exactly when economic agents perceive uncertainty and which type of uncertainty interests them. This paper introduces and outlines a way of conducting large-scale data searches on the Web. We create the EURQ index of “economic uncertainty related queries” for both the USA and Italy. We show that the EURQ encapsulates agents’ need to gather more information during periods of uncertainty. This need either spontaneously arises in the case of macro-real and political uncertainty, or is induced by the media in the case of normative and financial uncertainty. This distinction is extremely important when trying to understand the immediate impact of fiscal policy uncertainty on economic variables, and how financial shocks can produce a significant short-term impact on economic activity. It is also helpful when trying to solve the identification and endogeneity issues encountered in the literature when assessing the role of uncertainty.
N93-20175 Recursively Indexed Differential Pulse Code Modulation*

We study the performance of a DPCM system with a recursivelyindexed quantizer (RIQ) under various conditions, with firstorder Gauss-Markov and Laplace-Markov sources as inputs. We show that when the predictoris matched to the input, the proposed system performs at or close to the optimum entropy constrained DPCM system. We also show that the ifwe are willing to accept _ 5% increasein the rate,the system isvery forgiving of predictor mismatch. 1. well the predictor exploits closely can 2. How is
ON BOUNDED APPROXIMATION PROPERTIES OF BANACH SPACES

This survey features some recent developments concerning the bounded approximation property in Banach spaces. As a central theme, we discuss the weak bounded approximation property and the approximation property which is bounded for a Banach operator ideal. We also include an overview around the related long-standing open problem: Is the approximation property of a dual Banach space always metric?
Characterization of Lipids in Myctophid Fish in the Subarctic and Tropical Pacific Ocean

Lipids in 26 samples including the 20 species of myctophid fishes (Family Myctophidae) caught in the western subarctic and tropical Pacific Ocean were characterized. Myctophid fishes contained lipids at the level of 0.5 to 21.7% and were classified into three groups by lipid class composition, i.e., triglyceride-rich (5 species), wax ester-rich (3 species) and phospholipid-rich (12 species) groups. No fish which is rich in both triglycerides and wax esters was observed in the present study. The triglyceride-rich and wax ester-rich groups were found in the western subarctic Pacific, i.e., the Oyashio species, while the phospholipid-rich group with low-lipid content was found in the tropical species, i.e., the Equatori al and Central Water species. Three species, Stenobrachius leucopsarus, Lampanyctus regalis and Stenobrachius nannochir, contained wax esters with 30 to 44 carbon chain lengths as the major lipids, always accounting for more than 90% of total lipids. The main alcohol moieties of wax esters were 16:0, 20:1 and 22:1, while oleic acid (18:1n-9) and other monoenoic acids were predominantly fatty acids. Lipid composition analyses suggested the tendency that wax esters are rich in non-migratory or partly-migratory species.
Comparison of Radiotherapy Techniques in Breast Cancer with Inclusion of Internal Mammary Nodes through Thermoluminescent Dosimetry in a RANDO Phantom

Article type: Original Paper Introduction: In various radiotherapy techniques for breast cancer, the inclusion of internal mammary nodes (IMNs) in the target volume is important for selecting the most appropriate technique. This study aimed to compare three radiotherapy techniques with the inclusion of IMNs regarding the dose homogeneity index (DHI) of regional lymph nodes and the chest wall, besides the dose received by the heart and the left lung. Material and Methods: Three radiotherapy techniques were planned for CT imaging of the RANDO phantom, including the wide tangent (WT); oblique parasternal photon (OPP); and oblique parasternal electron (OPE) techniques. The doses reaching the contoured organs were compared between the three techniques, using the data gathered from the thermoluminescent dosimetry and treatment planning system. Results: The OPE technique produced a lower absorbed dose for the left IMNs, compared to the other two techniques. In the OPP technique, the dose received by the left lung was higher than its tolerance, while the lung dose in the OPE technique was slightly lower than the WT technique. The absorbed dose by the heart was the lowest in the WT technique; also, the DHI value was better for this technique than the other two techniques. Conclusion: The WT technique showed better results regarding the dose homogeneity distribution of IMNs and the chest wall, as well as protection of organs at risk. Article history: Received: Dec 09, 2019 Accepted: May 14, 2020
Utilization Biomass and Coal Mixture to Produce Alternative Solid Fuel for Reducing Emission of Green House Gas

This paper presents the characteristics of bio-briquette resulted from a series process using a mixture of raw materials. As raw materials of biobriquette production, this research used biomass corn cobs and banana peels, and a fine coal waste. Before using as component in the biobriquette, corn cobs, banana peels, and fine coal waste were carbonized. The carbonation process was carried out in temperature of 300-500 o C for 15 minutes. Carbonized corn cobs, banana peels, and a fine coal waste were characterized for calorific value and ash content. In this work, the influence of composition carbonized biomass and carbonized coal has been investigated. Before and after carbonization of biomass and coal, the calorific value and ash content of corn cobs were 4,239-6,386 kcal/kg and 3.47-8.12 % adb respectively, for banana peels were 4,135-6,042 kcal/kg and 16.99-32.31 % adb respectively, and for coal were 5,857-6,330 kcal/kg and 5.81-6.64 % adb respectively. The highest calorific value of biobriquette of 6,297 kcal/kg, highest fixed carbon content of 62.62 %, lowest volatile matter content of 26.18 % adb, lowest inherent moisture content of 5.14 % adb and lowest ash content of 6.06 were measured for composition of carbonized coal, carbonized corn cobs and carbonized banana peels ratio was of 1:4:0.
Appl. Entomol. Zool. 40 (1): 161–168 (2005)

Three cucurbitaceous feeding leaf beetle species, Aulacophora indica, A. lewisii, and A. nigripennis, were investigated with regard to the relationship between feeding preference by the beetles and cucurbitacins B, E, I, and E-glucoside contents in the leaves of 18 cucurbitaceous plant species. HPLC analysis and TLC analysis of A. lewisii revealed that the cucurbitacin B and E-glucoside, which are strong feeding stimulants for A. indica and A. lewisii, were abundant in Lagenaria siceralia, Sicyos angulatus, and Cucumis melo leaves. In a feeding preference test using fresh leaves, A. indica preferred various cucurbitaceous plant species and methanol extracts regardless of the contents of the four cucurbitacins. A. lewisii mostly fed on Luffa cylindrica leaves in which the four cucurbitacins were not detected. A. lewisii was also stimulated to feed by the methanol extracts of Lagenaria siceraria and L. cylindrical, while A. nigripennis, which is only slightly stimulated to feed by the four cucurbitacins, fed primarily on Trichosanthes kirilowii var. japonica leaves. Among 18 cucurbitaceous plants, only Diplocyclos palmatus leaves were completely rejected by the three beetle species, and these beetle species did not even feed on D. palmatus leaves treated with the cucurbitacins. These results indicate that some leaf constituents as well as the four cucurbitacins play an important role in host plant selection by the three cucurbitaceous feeding beetle species.