Miracle-dz/UniFAR-FTUs huggingface dataset:
Effect of moxibustion on cardiac remodeling and myocardial function in rats with exercise-induced fatigue

Objective: To explore the effect of moxibustion at Shenque(CV8) on myocardial structure and function in rats with exercise-induced fatigue. Methods: A 12-week treadmill training program was used to establish a rat model of exercise-induced fatigue. Fifty-six male SD rats removed six rats that did not reach the molding condition, Remaining rats were randomly divided into the following five groups: a normal group (n=10) that did not under go the exercise routine and were not treated, a control group (n=10) that did not under go the exercise routine, but received a mild dose of moxibustion at “Shenque” (CV 8) for 15 min, an untreated group (n=10) that received no treatment after exercise, a CV 8 group (n=10) that received a mild dose of moxibustion at “Shenque” (CV 8) for 15 min after exercise, a non-acupoint(tail) group(n=10) that received a mild dose of moxibustion at “non-acupoint” for 15 min after exercise. At one hour after the end of the 12-week training program, the left ventricular diastolic volume (LVDV), left ventricular systolic volume (LVSV), peak early diastolic mitral blood flow velocity (E), and peak late diastolic mitral blood flow velocity (A) were measured,and the E/A ratio were calculated. The serum myoglobin (Mb), creatine kinase-muscle/brain (CK-MB), and cardiac troponin-I (cTnI) levels were detected using an automatic biochemical analyzer. Results: When the values obtained before and after treatment were compared within the same groups, the LVDV, LVSV, E, and A were increased (P<0.05 or P<0.01), and the E/A were decreased (P<0.01) in the untreated group and the tail group. Regarding inter-group comparisons, the LVDV, LVSV, E, and A were increased (P<0.05 or P<0.01), and the E/A were decreased (P<0.01) in the untreated group and the tail group compared to the normal group and control group. Compared to the untreated group and the tail group, the LVDV, LVSV, E, and A were decreased (P<0.01) and the E/A were increased (P<0.01) in the CV 8 group. Compared to the normal group and the control group, the serum Mb, CK-MB, and cTnI levels were increased (P<0.01) in the untreated group and the tail group, and the serum Mb and CK-MB levels were also increased (P<0.01) in the CV 8 group. Compared to the untreated group and the tail group the serum Mb, CK-MB, and cTnI levels in the CV 8 group were decreased (P<0.01). Conclusions: Moxibustion at Shenque(CV8) can effectively prevent cardiac structural changes caused by exercise-induced fatigue and enhance heart function. This treatment does not have side effects in healthy rats and is a safe and effective technique.
Emotional Security and Social Competence among Syrian Refugee Children with Learning Disabilities

Emotional security and social competence are considered crucial psychological factors that affect the learning process, especially among vulnerable groups such as refugees and people with disabilities. This study aimed to identify the level of emotional security and social competence among Syrian refugees' children with learning disabilities. To achieve this objective, a descriptive-analytical approach was used to identify the level of emotional security, and social competence among (161) Syrian refugee children with learning disabilities enrolled in resource rooms in schools in the Zarqa Governorate, Jordan. The participants responded to emotional security and social competence scales. The results showed statistically significant differences in emotional security among Syrian refugees' children with learning disabilities attributed to their gender in favor of female children. At the same time, there was no difference in emotional security level based on parental status. The results also revealed statistically significant differences in social competence level based on the parental status for those who live with their parents. In general, the results showed a positive correlation between emotional security and social competence in children with learning disabilities from refugees. This study highlights the importance of conducting training programs to increase the level of emotional security, academic skills, and social behavior among refugee children with learning disabilities.
REDISTRIBUTION OF PARTICLES ACROSS THE NUCLEUS OF COMET 67P/CHURYUMOV-GERASIMENKO

We present an investigation of the surface properties of areas on the nucleus of comet 67P/Churyumov-Gerasimenko. Aims. We aim to show that transport of material from one part of the cometary nucleus to another is a significant mechanism that influences the appearance of the nucleus and the surface thermal properties. Methods. We used data from the OSIRIS imaging system onboard the Rosetta spacecraft to identify surface features on the nu- cleus that can be produced by various transport mechanisms. We used simple calculations based on previous works to establish the plausibility of dust transport from one part of the nucleus to another. Results. We show by observation and modeling that “airfall” as a consequence of non-escaping large particles emitted from the neck region of the nucleus is a plausible explanation for the smooth thin deposits in the northern hemisphere of the nucleus. The consequences are also discussed. We also present observations of aeolian ripples and ventifacts. We show by numerical modeling that a type of saltation is plausible even under the rarified gas densities seen at the surface of the nucleus. However, interparticle cohesive forces present difficulties for this model, and an alternative mechanism for the initiation of reptation and creep may result from the airfall mechanism. The requirements on gas density and other parameters of this alternative make it a more attractive explanation for the observations. The uncertainties and implications are discussed.
Research Note: Reconstruction of seismic signals using S‐transform ridges

We have addressed the problem of seismic data frequency–time filtration based on the S‐transform. The S‐transform provides frequency‐dependent resolution while maintaining a direct relationship with the Fourier spectrum and has been widely used in different seismic data‐processing applications. The standard S‐transform filtration method is based on its invertibility. In a sense of time localization, this method is not optimal because the calculation of the inverse S‐transform includes time averaging. We propose an alternative filtration method based on the reconstruction of a signal by S‐transform ridges. We approximate the phase of the Fourier spectrum of the reconstructed signal using the phase of the S‐transform ridge. We derive the integral equation, which expresses the S‐transform ridge amplitudes in terms of the amplitudes of the Fourier spectrum of the reconstructed signal. The introduced equation is numerically solved to find the signal amplitude using the truncated singular value decomposition. From the results, we obtain both the phase and amplitude of the signal. Thus, the signal can be extracted from the S‐transform spectrum only by the ridges. This finding is promising in terms of maximum usage of the time‐localization properties of the S‐transform during frequency–time filtration. The presented results of ground‐roll attenuation from reflection seismic data demonstrate that the proposed S‐transform ridge filtration method can be effective in practice.
Thromboembolism in Muscle-Invasive Bladder Cancer. A Population-based Nationwide Study

BACKGROUND: Routine VTE prophylaxis within 30 days of radical cystectomy (RC) for urinary bladder cancer (UBC) is used to protect from venous thromboembolism (VTE). However, randomized studies and nationwide population-based studies are lacking. ∗Correspondence to: Staffan Jahnson, Department of Clinical and Experimental Medicine, Division of Urology, Linköping University, Linköping, Sweden, Tel. : +46708608234; Fax: +4613227445; E-mail: staffan.jahnson@gmail.com. ISSN 2352-3727 © 2021 – The authors. Published by IOS Press. This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (CC BY-NC 4.0). 162 S. Jahnson et al. / Thromboembolism in Invasive Bladder Cancer OBJECTIVE: To study VTE and risk factors for VTE in muscle-invasive UBC in a nationwide population-based series, with a focus on the association with RC with and without chemotherapy. MATERIALS AND METHODS: We studied all patients with clinical stage T2-T4 UBC diagnosed 1997 to 2014 in the Bladder Cancer Data Base Sweden (BladderBaSe). Previous VTE events and risk factors for VTE were registered from 1987. Cox regression analyses and Kaplan-Meier curves were performed to study risk factors for VTE and cumulative incidence of VTE. RESULTS: In 9720 patients (71% males) with a median age of 74 years 546 (5.6%) had VTE after diagnosis. In Cox analyses controlling for patient’s and tumour characteristics, and risk factors for VTE, VTE after diagnosis and first treatment date were associated with chemotherapy with or without RC. Cumulative incidence of VTE increased during 24 months after diagnosis and first treatment date. VTE were less common in patients with previous cardiovascular disease. CONCLUSION: VTE was commonly observed after 30 days from diagnosis and from first treatment date in patients with T2-T4 UBC, particularly after chemotherapy. The findings suggest that long-term intervention studies of benefit and possible harms of VTE prophylaxis after UBC should be undertaken.
Increased Carvone Production in Escherichia Coli by Balancing Expression of Limonene Conversion Enzymes Through Targeted QconCAT Proteome Analysis

Background Natural mint flavor is produced by extraction from mint, which is not efficient enough to make it environment friendly process. (−)-Carvone is the monoterpenoid with key flavor of spearmint, and there has been an attempt to produce (−)-carvone by recombinant Escherichia coli. Although all enzymes in (−)-carvone biosynthesis have been functionally expressed in E. coli independently, the yield of (−)-carvone was low in the previous study.ResultsWe have found a by-product formation when cytochrome P450 limonene-6-hydroxylase (P450)/cytochrome P450 reductase (CPR) and carveol dehydrogenase (CDH) were expressed in single cell. These by-products were determined as dihydrocarveol and dihydrocarvone. We hypothesized that the enzymatic kinetics and the expression levels of P450 and CDH are quite different in E. coli. Therefore, two strains independently expressing P450/CPR and CDH were mixed with different mixing ratio, confirming increase in carvone production and decrease in by-product formation when CDH input was reduced. To determine the optimum balance of enzyme expressions, proteome analysis quantification concatemer (QconCAT) method to quantify P450, CPR, and CDH was developed. Using the QconCAT standard protein that was artificially created by concatenating the tryptic peptides, the ratio between P450 and CDH was calculated, and their optimum ratio to maximize (−)-carvone production was shown. Then, a single strain expressing both P450/CPR and CDH was constructed to imitate the superior expression ratio. The upgraded strain showed 15-fold improvement compared to the initial strain, showing 44 ± 6.3 mg/L of (−)-carvone production from 100 mg/L (−)-limonene as a starting substrate.ConclusionsImproved expression balance of P450 and CDH in recombinant E. coli increased the (−)-carvone production using (−)-limonene as the direct substrates by the whole-cell biocatalysis, showing approximately 150 times higher titer than previous report. Our study showed the usefulness of proteome analysis QconCAT method in the strain development for industrial biotechnology field.
The Increasing Self-Efficacy and Self-Regulated through GeoGebra Based Teaching reviewed from Initial Mathematical Ability (IMA) Level

The purpose of this study was to identify improvements in Self Efficacy and self-regulated through GeoGebra Based Teaching seen from the level of students' initial mathematical abilities. The research method used was a mixed-method with a sequential explanatory strategy, while the research design was an untreated control group design with pretest and posttest. the experimental group obtained direct learning using GeoGebra software while the control group obtained conventional learning. The population in this study were university students of mathematics education department at the Islamic University of Riau who took the field and space analytic geometry course. The research sample consisted of two classes taken by a cluster random sampling technique. The research instruments used were self-efficacy questionnaire and self-regulated questionnaire for getting quantitative data and interview guidelines for getting qualitative data. Data analysis was carried out quantitatively and qualitatively and data processing used Microsoft excel and SPSS from the quantitative and qualitative data analysis, it was concluded that GeoGebra based teaching was effective in improving students' self-efficacy and self-regulated. Judging from the level of students' initial mathematical abilities, there was an increase in self-efficacy and self-regulated through GeoGebra based teaching from both high, medium and low levels.
Actitud de los profesores ante el uso de las TIC en la Facultad de Ciencias Médicas de Matanzas

Introducción: El perfeccionamiento continuo del sistema educativo cubano, que tiene lugar en los últimos años, condiciona la necesidad de renovar, en el marco de los Centros de Educación Superior, los planes de estudios desde una perspectiva que responda a las exigencias asociadas al proceso de Universalización de la Educación que en ellos tiene lugar, lo cual implica que la universidad como institución social dirija su trabajo a alcanzar resultados prominentes; en la introducción, innovación y creación de tecnologías Objetivo: Valorar la actitud de los profesores ante el uso de la TIC en la Facultad de Ciencias Médicas de Matanzas. Metodología: Se realizó un estudio cuantitativo en la Facultad de Ciencias Médicas de Matanzas en el período de enero –mayo del 2019, para evaluar la actitud de los profesores, ante el uso que realizan de las TIC los profesores de la Facultad de Ciencias Médicas de Matanzas. Resultados: Los resultados mostraron que los profesores de la Facultad de Ciencias Médicas de Matanzas poseen una actitud excelente ante el uso de las tecnologías de la información y las comunicaciones en la docencia de pregrado Conclusiones: Sin duda las nuevas tecnologías pueden suministrar medios para la mejora de los procesos de enseñanza aprendizaje pero su utilización a favor o en contra de una sociedad más desarrollada, dependerá en gran medida de la actitud, de los profesores como guías principales del proceso
Dynamic capabilities and entrepreneurial performance of Chinese start-ups: the mediating roles of managerial attitude towards risk and entrepreneurial behaviour

ABSTRACT This paper analyses the sequential mediation effects of managerial attitude towards risk and entrepreneurial behaviour on the relationship between dynamic capabilities and entrepreneurial performance in the Chinese context. Our proposed model explains the key micro-level mechanisms through which dynamic capabilities drive entrepreneurial performance and the varying effects of entrepreneurial orientation dimensions on performance, thus, enabling decision-makers to understand how to utilize dynamic capabilities to achieve desirable performance. Drawing on survey data of 250 new ventures across different industries in China, we find that dynamic capabilities have both a direct positive effect and an indirect effect on entrepreneurial performance through the chain mediation effects of managerial attitude towards risk and entrepreneurial behaviour.
Beyond Classroom English Activities to Generate Interest in English Among Tertiary Students

In this article, we present a study aimed to explore the attitude, interest and perception of students learning English language beyond the classroom using a list of activities such as Readers Theatre, Storyboard, Academic Explorace, Spell it right and Melodies of Pilah. A survey was conducted involving 466 students from different faculties who were taking English proficiency courses at diploma and degree levels at a local university. The findings indicate that both male and female students had a positive degree of interest and attitude toward the English activities carried out beyond the classroom. The popular activities were Readers Theatre and Melodies of Pilah (group singing). The study also indicated that students preferred group activities compared to individual activities. Based on the findings, it is recommended that students should be allowed to explore English materials independently beyond classrooms where language learning takes place implicitly. The study found that the success of English learning activities carried out beyond the confines of the classroom can generate interest among students to learn the language. The success of English activities carried out beyond classrooms can be assessed by students’ ability to complete the task assigned (the end-product) rather than the processes involved in completing the task.
Probable antioxidant therapy of Saffron Crocin in patients with multiple sclerosis: A randomized controlled trial

Introduction and Aim: Multiple Multiple sclerosis (MS) is a complex neurological condition might emerge as a result ofcomplex combination of genetic risk factors with environmental triggers, including oxidative stress. in this study we aimed to evaluate the effects of oral Crocin on oxidative stress in patients with MS. Materials and Methods: Adjunct to standard treatment, the Crocin group (20 patients) received 30-mg/day (15 mg twice daily) dose of Crocin and placebo group (20 patients) received for 4 weeks. Saliva and urine samples were collected to determine the levels of total antioxidant capacity (TAC), catalase activity (CAT), total thiol groups (TTG), lipid peroxidation (LPO), were measured at baseline and the end of the study. Results: At baseline, there were no significant differences of LPO, TAC, CAT, and TTG of urine between the control and case groups. However, a significant difference was found after 4 weeks of Crocin-therapy in TTG,TAC and LPO (p<0.05) except in CAT activity (P>0.05). We found no deffrence in urinary TTG level and CAT activity in control group at the end of intervention (P>0.05), while TAC and LPO level were significantly different at the end of the study as compared with the beginning (P<0.05). Althugh, we found no significant difference in saliva LPO, TTG and TAC levels and the activity of CAT in case and control groups at first (p>0.05), Crocin administration have resulted in a significant increase in saliva TTG and TAC levels as well as CAT activity and markedly decrease in LPO level (p<0.05). Conclusion: According to the results of this study, Crocin can significantly reduce the several oxidative stress factors in MS patients and may contributes to attenuates the oxidative damages.
Entry and Exit, Unemployment, and the Business Cycle

Establishment entry and exit is strongly correlated with output and unemployment. This paper examines how these linkages affect business cycle dynamics through the lens of a search and matching model augmented to include multi-worker establishments that endogenously enter and exit. Analytical results show cyclical entry and exit cause reallocation of inputs that amplifies and skews business cycle dynamics. When the model is calibrated to the data, it generates realistic asymmetry in output and unemployment, data-consistent counter-cyclical endogenous uncertainty, and a 55% higher welfare cost than the model without entry and exit.
Unlocking the Potential of 5G and Beyond Networks to Support Massive Access of Ground and Air Devices

Flying devices, e.g., Unmanned Aerial Vehicles (UAV) and High Altitude Platforms (HAP) are showing great potentials to revolutionise human society with unprecedented efficiency and convenience. 5G and beyond (5 GB) networks have been considered as an important infrastructure for supporting flying devices to accomplish mission-critical applications. However, most of the existing research on 5 GB networks mainly focuses on technology evolution to support ground devices, paying insufficient attention to the emerging large-scale deployment of flying devices. To fill the gap, this study aims to identify the differences when 5 GB networks are used to provide massive access services for the ground devices and their counterpart flying in the air and analyse in which aspects that 5 GB should be enhanced to serve flying devices. In detail, a holistic 5 GB architecture is presented to support both ground and flying devices. Then, the unique features of flying devices are analysed with a focus on the challenges they bring to 5 GB systems. Facing these challenges, we thoroughly investigate the advantages and disadvantages of 5 GB key technologies. Furthermore, a case study is presented to demonstrate that flying devices not only create new issues for 5 GB design, but also bring new opportunities for 5 GB to enhance their service capabilities.
MODELING NUCLEAR DATA UNCERTAINTIES USING DEEP NEURAL NETWORKS

A new concept using deep learning in neural networks is investigated to characterize the underlying uncertainty of nuclear data. Analysis is performed on multi-group neutron cross-sections (56 energy groups) for the GODIVA U-235 sphere. A deep model is trained with cross-validation using 1000 nuclear data random samples to fit 336 nuclear data parameters. Although of the very limited sample size (1000 samples) available in this study, the trained models demonstrate promising performance, where a prediction error of about 166 pcm is found for keff in the test set. In addition, the deep model’s sensitivity and uncertainty are validated. The comparison of importance ranking of the principal fast fission energy groups with adjoint methods shows fair agreement, while a very good agreement is observed when comparing the global keff uncertainty with sampling methods. The findings of this work shall motivate additional efforts on using machine learning to unravel complexities in nuclear data research.
Utilization of Enzyme Supplemented Wheat offal-rice bran based diets on performance characteristics and serum biochemistry by meat-type chicken

An experiment was conducted to investigate the effect of exogenous enzyme supplementation on the utilization of rice bran as a replacement for wheat offal by meat-type chicken. A total of three hundred and twenty day-old Marsha strain broiler chickens were randomly allocated to eight dietary treatments. Each dietary treatment had 40 birds with 10 birds in each replicate. The wheat offal in diets was replaced by rice bran (RB) at four levels (0%, 10%, 20 % and 30%). Each diet contained 2853.10, 2837.90, 2822.70, and 2807.50 ME Kcal/kg and Crude Protein% of 21.68, 21.57, 21.47 and 21.36. The diets were in two groups. One group was supplemented with exogenous Enzyme while the other group was not supplemented with enzyme. The growth performance, serum biochemistry and organ weight were estimated Data obtained were subjected to Analysis of variance in a 2 x 4 factorial arrangement, Results showed that the final body weight gain was significantly higher (P at this level. Birds fed 30% rice bran inclusion level had significantly lower (P Protein, Globulin and Serum Glutamate Oxaloacetate Transaminase (SGOT). Birds on diet containing level of rice bran had high total protein, Globulin and SGOT [t was concluded that 30% rice bran With enzyme supplementation had no adverse effect on the performance, serum biochemistry and internal organs of the birds.