Miracle-dz/UniFAR-FTUs huggingface dataset:
Evaluation of Intralesional Injection of 5-fluorouracil in Treatment of Vitiligo

Background: Vitiligo is a chronic cutaneous disease characterized by depigmented patches that leave psychological impact on the patients. New treatment modalities have been developed to improve the results vitiligo with less side effects. Objective: To evaluate intralesional injection of 5-fluorouracil in treatment of vitiligo. Patients and Methods: The study included 20 localized stable vitiligo patients. Each patient was treated with intralesional injection of 5-fluorouracil every 2 weeks for 3 sessions followed by narrow band sessions twice weekly for 3 months. Results: There was statistically significant repigmentation after treatment with intralesional 5-FU (mean of 50.30 ± 34.60, P value =0.001 Wilcoxon signed ranks test between before and after). 55% of patients showed >50% repigmentation. after 3 months therapy. Side effects were minimal and transient. Conclusion: Intralesional injection of 5-FU is safe and effective in the treatment of vitiligo.
Key Parameters of Preventing Spontaneous Combustion of Coal Stockpile Based on Heat Transfer Technology by a Heat Pipe

ABSTRACT Over the past few decades, the spontaneous combustion of large-scale coal stockpile is frequent due to natural airflow contacted the surface and entered in the voids of coal stockpile, coal is oxidized and accumulated the heat, and then coal spontaneous combustion occurred, which seriously caused the waste of natural resources and environmental pollution. In this study, based on the principle of heat transfer by heat pipe (HP), an experiment is conducted to study the effect of heat transfer by HP, such as the temperature difference and heat transfer ratio, heat transfer radius, cumulative heat transfer volume, in a coal stockpile as its heating temperature increased from 100°C to 150°C under the different lab conditions. The results indicated that the average temperature drop scale in the coal stockpile by HP was 46.3%, 10.8%, and 32.8% that under the lab conditions, respectively. A comparison study revealed that as the inserted angle of HP in the coal stockpile is 60º, the heat transfer effect of HP is significantly affected by outside ambient, especially sensitive to airflow. For instance, as the HP inserted scale is 1:4, outside air velocity is 2.0 m/s, the maximum heat transfer radius in the coal stockpile is 49.2 cm, the overall heat transfer effect enhanced by 79% and 93% that with the heating temperature in the coal stockpile is 100°C and 150°C, respectively. Therefore, it can be concluded that the utilization of HP is a reasonable method to remove the accumulated heat in the coal stockpile, as well as the suitable arrangement is also significantly important before this technique is conducted. This study provided a new technical approach and theoretical basis for the prevention and control before the large-scale stockpile has the risk of spontaneous combustion.
Knowledge and Feelings of Competence with Regard to ADHD Among Support Staff in All-Day Primary Schools

(1) Background: Schools report a high number of schoolchildren with poor attention and hyperactive behavior, with 5% being diagnosed with attention deficit/hyperactivity disorder (ADHD). This causes specific problems during homework and classroom times, and the extension of all-day schooling in German primary schools makes this a challenge for support staff working in the after-school programs. Such staff have a very wide variety of qualifications, ranging from no formal teacher training to full teaching qualifications. (2) Methods: This study documents the knowledge of 196 support staff working in all-day primary schools about ADHD, and their subjective view of whether they feel competent with regard to homework situations in general and ADHD in particular. (3) Results: Those with an educational background have significantly more knowledge than those without such a background, staff feel less prepared to supervise children with ADHD, and there is a small but significant correlation here with knowledge about ADHD. (4) Conclusions: The importance of trained pedagogical staff in the supervision of children with concentration problems is emphasized.
Evaluation of ph stability, concentration and antimicrobial activity in commercial brands of sodium hypochlorite solution

The present work refers to an in vitro study of different commercial brands of sodium hypochlorite (manipulated, Soda Chlorine and Brilux) being evaluated by means of pH, antimicrobial action and concentration, at time intervals of 0, 7 and 14 days, in a refrigerated environment and at room temperature, and with receiving and absence of light. The antimicrobial assay of the solutions was performed by the disk diffusion method. Enterococcus faecalis was grown on Tryptic Soil Agar (TSA) (Merk) and incubated at ± 35oC for 24 hours. The active chlorine content was verified by iodometric titration, and the pH, by pH measuring tape. The results suggest that there was no statistically significant relevance in the results of the active chlorine content. The pH became higher with time, and the antimicrobial activity was altered according to the storage location and time.
How to derive a geovisualization from an application data model: an approach based on Semantic Web technologies

ABSTRACT While ontological modelling and Semantic Web technologies are sometimes used to describe knowledge domains with a spatial component, there is still a lack of semantics to describe how to present this knowledge geovisually to the end user and how to automatize the process. In this paper, we first present vocabularies to describe at a high level the elements that make up a geovisualization. We then propose a method that describes at a semantic level how to obtain a geovisualization from an existing data model. This method is based on our vocabularies and on a set of semantic rules encoding rich and complex operations on data. This leads to the derivation of ontological knowledge, ready to be exploited to automate the creation of a geovisualization. The method is implemented in a framework that uses Semantic Web technologies. The singularity and the strength of our proposal is that it enables to describe a geovisualization through a RDF specification file, which once loaded in our system makes the geovisualization directly available for use from a Web browser. This result is obtained by extending a priori an application data model with ad hoc geovisualization semantics features and rules.
Formulating diets based on whole cassava tuber (Manihot esculenta) and gliricidia (Gliricidia sepium) increased feed intake, liveweight gain and income over feed cost of Ongole and Bali bulls fed low quality forage in Central Sulawesi, Indonesia

Context Formulating rations with high energy and protein feeds such as cassava tuber and gliricidia, is an important strategy to increase liveweight gain (LWG) of bulls and improve profitability of smallholder farmers in Indonesia. Aims Two on-farm experiments were conducted to evaluate the effect of increasing the supplementation level of a mixture of cassava (Manihot esculenta) whole root tuber powder and fresh gliricidia (Gliricidia sepium) on feed intake and LWG of Ongole and Bali bulls given fresh corn stover and elephant grass, respectively. Methods Two experiments were conducted, each with five treatments: a basal diet of fresh corn stover (Experiment 1 for Ongole bulls) or elephant grass (Experiment 2 for Bali bulls) fed ad libitum or this diet supplemented with a combination of cassava tuber (whole root tuber including peel, sun-dried and ground) and fresh, chopped gliricidia (1:1) on estimated dry matter (DM) basis, at DM levels of 0.4, 0.8, 1,2 and 1.6% liveweight (LW)/day. Each experiment was run for 18 weeks, consisting of a two week adaptation and 16 week experimental period. Parameters measured included basal DM intake, supplement DM intake, total DM intake, total water intake, faecal pH, daily LWG, feed conversion ratio (FCR) and income over feed cost (IOFC). Key results Increasing supplement level linearly (P < 0.05) decreased basal diet intake, but linearly increased total DM intake and LWG (P < 0.05) in both breeds. Basal diet DM intake was reduced at the rate of 0.43 kg/kg of supplement DM consumed for both Ongole and Bali bulls. Water intake and faecal pH were not affected (P > 0.05) by increasing supplement intake. Inclusion of cassava tuber and gliricidia supplement up to 1.6% LW/day, increased total feed DM intake (up to 3.28 and 3.18% LW/day, for Ongole and Bali bulls, respectively) and LWG (maximum Ongole bulls 0.69 kg/day and Bali bulls 0.46 kg/day). Daily income over feed cost (IOFC) increased significantly (P < 0.05) in association with increased supplement intake in both Experiments 1 and 2. Using the derived model without supplementation, the value of IOFC was only IDR 7802/day and IDR 7687/day, for Experiments 1 and 2, respectively. The highest IOFC was achieved at a supplement intake of 1.6% LW/day with values of IDR 13949/day and IDR 12543/day for Experiments 1 and 2 respectively. Conclusions The addition of a cassava tuber and gliricidia mixture up to 1.6% LW/day increased LWG and profit for smallholders fattening bulls. Implications Formulating a ration with cassava tuber and gliricidia can be economically beneficial in cattle fattening systems in Indonesia.
Minority stress and sexual minorities of colour: the mediating role of mastery

ABSTRACT The minority stress model states that routine forms of discrimination are associated with adverse health consequences. Despite this well-supported association, there is a limited body of research applying this model for sexual minorities of colour. We utilise an intersectional approach to investigate how minority stress at the intersection of sexual and racial identities impacts psychological health outcomes. In the current study, we examine how various sources of minority stress (perceived stigma, internalised homophobia, and everyday discrimination) are associated with psychological health, through an indirect effect of mastery (Study 1) in addition to authenticity (Study 2) in two independent samples of sexual minorities of colour. Study 1 (n = 262) included sexual minorities of colour from Project STRIDE, and in Study 2, participants (n = 75) were recruited across several online platforms. Mediation analyses revealed that increased minority stressors, like discrimination, were significantly associated with a decrease in psychological health, through a decline in mastery. We did not find support for authenticity as a mediator. This study has important implications for understanding the experiences and health consequences for sexual minorities of colour.
The contingent value of managerial ties for new ventures during China’s anti-corruption campaign

ABSTRACT The tie-based non-market strategy has been widely adopted by new ventures to gain a competitive advantage in China. However, the recent anti-corruption campaign may have profound influences on business practices, particularly on the utilization or leveraging of managerial ties for improving firm performance. This study explored the critically important but fairly underexplored research question of whether managerial ties continue to create value for new ventures under China’s anti-corruption campaign. Based on a sample of Chinese listed firms consisting of new ventures, this study found that business ties and political ties have produced divergent effects on the performance of new ventures since China’s anti-corruption campaign took effect. Moreover, a wider coverage or scope of anti-corruption increased the benefits of business ties and political ties, while a higher intensity of anti-corruption facilitated the role of anti-corruption scope on increasing the benefits of managerial ties for better performance of new ventures.
Cover crops in viticulture. A systematic review (1): Implications on soil characteristics and biodiversity in vineyard

This work seeks to synthesise the knowledge on the use of cover crops in vineyards in the last 20 years, emphasising on the one hand, soil characteristics such as nutrition, organic carbon, structure or erosion and, on the other hand, environmental factors such as soil and biodiversity in vineyards, and gas emissions.A systematic review was made using Scopus-index journals for the past 20 years (1999 - 2018). The selection was independently done by two researchers, selecting a total of 272 published papers related to cover crops in the vineyard. Each article was categorised according to its theme and metadata were created, considering all relevant information from an agro-ecological point of view.The use of cover crops has a positive effect on the vineyard by increasing soil organic carbon (SOC), improving water infiltration and aggregate stability, and reducing erosion and greenhouse gases emission to the atmosphere. Furthermore, there is an increase in biodiversity, both in soil and the vineyard. Finally, cover crops do not constitute as a rule a major competition for nutrients to the vines except for nitrogen when grass covers are used. Contrarily, legume cover crops generally increase N in the soil, although its availability for plants is not immediate.This review constitutes an objective tool to help growers when considering the use of cover crops in vineyards that, based in a systematic review, provides relevant information depending on the characteristics of the growing condition of the vineyard.
Micro-Mechanical Response of Ultrafine Grain and Nanocrystalline Tantalum

Abstract In order to investigate the effect of grain boundaries on the mechanical response in the micrometer and submicrometer levels, complementary experiments and molecular dynamics simulations were conducted on a model bcc metal, tantalum. Microscale pillar experiments (diameters of 1 and 2 μm) with a grain size of ∼ 100-200 nm revealed a mechanical response characterized by a yield stress of ∼1,500 MPa. The hardening of the structure is reflected in the increase in the flow stress to 1,700 MPa at a strain of ∼0.35. Molecular dynamics simulations were conducted for nanocrystalline tantalum with grain sizes in the range of 20-50 nm and pillar diameters in the same range. The yield stress was approximately 6,000 MPa for all specimens and the maximum of the stress-strain curves occurred at a strain of 0.07. Beyond that strain, the material softened because of its inability to store dislocations. The experimental results did not show a significant size dependence of yield stress on pillar diameter (equal to 1 and 2 um), which is attributed to the high ratio between pillar diameter and grain size (∼10-20). This behavior is quite different from that in monocrystalline specimens where dislocation ‘starvation’ leads to a significant size dependence of strength. The ultrafine grains exhibit clear ‘pancaking’ upon being plastically deformed, with an increase in dislocation density. The plastic deformation is much more localized for the single crystals than for the nanocrystalline specimens, an observation made in both modeling and experiments. In the molecular dynamics simulations, the ratio of pillar diameter (20-50 nm) to grain size was in the range 0.2 to 2, and a much greater dependence of yield stress to pillar diameter was observed. A critical result from this work is the demonstration that the important parameter in establishing the overall deformation is the ratio between the grain size and pillar diameter; it governs the deformation mode as well as surface sources and sinks, which are only important when the grain size is of the same order as the pillar diameter.
The Impact of Entrepreneurial Orientation on New Product Creativity, Competitive Advantage and New Product Performance in SMEs: The Moderating Role of Corporate Life Cycle

The current study aims to empirically examine the effect of entrepreneurial orientation on new product creativity, competitive advantage, and new product performance. Data are collected from 424 Small and Medium-sized Enterprises (SMEs) in South Korea. The suggested hypotheses are tested through the structural equation modeling technique. The analysis outcome shows that entrepreneurial orientation has a significant positive effect on both new product (NP) novelty and new product meaningfulness. The study further finds that both new product novelty and meaningfulness have significant positive impacts on competitive advantage, respectively, while the latter has a significant positive effect on new product performance. Similarly, the study finds that corporate life cycle significantly moderates the relationship between entrepreneurial orientation and new product meaningfulness. The study offers practical and theoretical insights into understanding entrepreneurship dynamics, new product creativity, and new product performance. The research shows that SME managers must adopt an entrepreneurial orientation at an early stage in the life cycle.
Lack of Association Between Patients Characteristics and the Carriage of Extended-spectrum β-Lactamase Producing Enterobacteriaceae in Community Settings in Blantyre, Malawi

Objective: This study examined factors associated with the carriage of extended-spectrum β-lactamase (ESBL) producing Enterobacteriaceae in community patients in Blantyre, Malawi. ResultsA total of 50 community patients with ESBL producing Enterobacteriaceae (ESBL-E) carriage were identified from 300 adults recruited in the study, which gave a prevalence of 16.67% (50/300, 95% CI=12.43-20.91%). The mean age ±SD was 32.41±12.07 years; range, 18-75 years and 54.33% (163/300) were women. The results of unadjusted logistic regression model fitted to identify factors associated with ESBL-E carriage in community patients showed that there was no any degree of association between carriage of extended-spectrum β-lactamase producing Enterobacteriaceae in community patients with either their demographic or clinical characteristics.
Active restoration leads to rapid recovery of aboveground biomass but limited recovery of fish diversity in planted mangrove forests of the North Brazil Shelf

Coastal degradation has spurred active restoration of mangrove ecosystems, from local initiatives to global commitments to increase mangrove forest area by 20% over the next decade. Mangrove restoration projects typically have multiple objectives, including carbon storage, coastal resilience, and fisheries recovery. How planting seedlings, the most common form of active restoration, can promote recovery of mangrove ecosystem functions remains an urgent research need. We quantified multiple ecosystem outcomes of Guyana's national mangrove restoration program, approximately a decade after seedling planting, and compared restoration outcomes with conditions in intact and degraded mangrove forests. Multivariate analyses indicate that intact and restored sites' environmental conditions were similar to each other but different from degraded sites. Aboveground biomass in restored sites (103 Mg ha−1) was 13 and 99% greater than intact (89.4 Mg ha−1) and degraded (0.12 Mg ha−1) sites, respectively. Active restoration successfully increased seedling abundance of both planted and unplanted species, with similar abundance between intact and restored sites. In contrast, fish communities in restored sites remained similar to degraded sites. Restored sites were dominated by a single algivorous fish species, with lower species diversity and commercially valuable fisheries than intact sites. Our results demonstrate that active restoration is a viable option to restore mangrove forest tree biomass and tree species composition in this region. However, even under a best‐case scenario for mangrove forest restoration, fisheries did not recover during our study's timespan. Long‐term monitoring and controlled experiments will be essential to further understand restoration outcomes for multiple ecosystem services in mangrove forests.
How Early? Worldwide Evidence from Early Mask Mandates and Other Policy Interventions on COVID-19 Infection and Death

The concept of agility underscores how fast actions, responsiveness to users’ experiences, and adaptive structures enable governments to address problems arising from rapidly changing environments. Applying the concept to government responses to COVID-19, we examine whether a government’s early mandate adoption enhances its eventual efficacy and how different policy instruments compare in both their short and long-run performance. Using worldwide data on the daily evolution of mandate adoption and virus progression, the analysis shows that the mask mandate, especially its early adoption, is consistently associated with lower infection rates in both short- and long-term. By contrast, the other five policy instruments—domestic lockdown, international travel ban, mass gathering ban, business, and school closure—show weaker efficacy. Agility is a critical dimension of policy instruments’ effectiveness, and not all interventions may have the same efficacy. To be agile, governments must weigh the relative efficacies of alternative policy instruments when designing mandates.
Service-Led or Service-Biased Growth? Equilibrium Development Accounting Across Indian Districts

In many developing countries today, the structural transformation is a shift of employment out of agriculture into the service sector. By contrast, industrial employment is mostly stagnant. Is the service sector an engine of growth and hence growth service led? Or is its expansion a mere corollary of growth, where rising incomes stemming from productivity growth in goods-producing industries increases the demand for services? To determine whether growth is service led or service biased, we estimate a spatial equilibrium model with nonhomothetic preferences. Our methodology is in the spirit of development accounting and lends itself to a quantitative assessment of both the aggregate and the heterogenous welfare effects of sectoral productivity growth. In an application to India, we find that productivity growth in consumer services such as retail and hospitality was an important driver of rising living standards between 1987 and 2011. However, such benefits were highly skewed and accrued mostly to high-income households living in urbanized locations. Institutional subscribers to the NBER working paper series, and residents of developing countries may download this paper without additional charge at www.nber. org.
COVID-19 and cardiovascular complications – preliminary results of the LATE-COVID study

Introduction Coronavirus disease 2019 (COVID-19) may affect many organs and may be responsible for numerous complications including cardiovascular problems. Methods We analysed consecutive patients (n = 51) admitted to the cardiology department between 1st October 2020 and 31st January 2021 due to symptoms which might have reflected cardiovascular complications following COVID-19. We collected data concerning clinical characteristics, results of laboratory tests, echocardiography and 24-hour ambulatory ECG recording. Results The post-COVID-19 complications appeared 1–4 months after disease recovery. Severe cardiovascular complications were observed in 27.5% of hospitalized patients. In comparison to those with mild complications, patients with severe complications had significantly higher prevalence of diabetes (36 vs. 8%; p = 0.01), decrease in ejection fraction (36% vs. 0%, p < 0.001), higher resting heart rate at admission (85 vs. 72 bpm; p < 0.001), and higher levels of C-reactive protein (p = 0.02) and troponin T (17.9 vs. 4.2 pg/ml; p = 0.01). Dyspnoea and exercise intolerance were also more frequent in patients with severe complications. Conclusions Diabetes, elevated level of CRP and troponin, heart rate variability parameters and worsening of left ventricular ejection fraction are related to the severity of cardiovascular complications following COVID-19 infection.