Miracle-dz/UniFAR-FTUs huggingface dataset:
How do explicit and implicit evaluations shift? A preregistered meta-analysis of the effects of co-occurrence and relational information.

Based on 660 effect sizes obtained from 23,255 adult participants across 51 reports of experimental studies, this meta-analysis investigates whether and when explicit (self-reported) and implicit (indirectly revealed) evaluations reflect relational information (how stimuli are related to each other) over and above co-occurrence information (the fact that stimuli have been paired with each other). Using a mixed-effects metaregression, relational information was found to dominate over contradictory co-occurrence information in shifting both explicit (mean Hedges' g = 0.97, 95% CI [0.89, 1.05], 95% PI [0.24, 1.70]) and implicit evaluations (g = 0.27, 95% CI [0.19, 0.35], 95% PI [-0.46, 1.00]). However, considerable heterogeneity in relational effects on implicit evaluation made moderator analyses necessary. Implicit evaluations were particularly sensitive to relational information (a) in between-participant (rather than within-participant) designs; when (b) co-occurrence information was held constant (rather than manipulated); (c) targets were novel (rather than known); implicit evaluations were measured (d) first (rather than last) and (e) using an affect misattribution procedure (rather than an Implicit Association Test or evaluative priming task); and (f) relational and co-occurrence information were presented in temporal proximity (rather than far apart in time). Overall, the present findings suggest that both implicit and explicit evaluations emerge from a combination of co-occurrence information and relational information, with relational information usually playing the dominant role. Critically, variability in these effects highlights a need to refocus attention from existence proof demonstrations toward theoretical and empirical work on the determinants and boundary conditions of the influences of co-occurrence and relational information on explicit and implicit evaluations. (PsycInfo Database Record (c) 2022 APA, all rights reserved).
An approach estimating bidirectional air‐surface exchange for gaseous elemental mercury at AMNet sites

The bidirectional air‐surface exchange for gaseous elemental mercury (GEM) and existing measurements of the compensation points over a variety of canopy types are reviewed. Deposition and emission of GEM are dependent on several factors such as the type of canopy, temperature, season, atmospheric GEM concentrations, and meteorological conditions, with compensation points varying between 0.5 and 33 ng m−3. Emissions tend to increase from the spring to summer seasons, as the GEM accumulates in the foliage of the vegetation. A strong dependence on solar radiation has been observed, with higher emissions under light conditions. A bidirectional air‐surface exchange flux model is proposed for estimating GEM fluxes at a two‐hourly time resolution for the National Atmospheric Deposition Program's, Atmospheric Mercury Network (AMNet) sites. Compared to the unidirectional dry deposition model used in Zhang et al. (2012), two additional parameters, stomatal and soil emission potential, were needed in the bidirectional model and were chosen based on knowledge gained in the literature review and model sensitivity test results. Application of this bidirectional model to AMNet sites have produced annual net deposition fluxes comparable to those estimated in Zhang et al. (2012) at the majority of the sites. In this study, the net GEM dry deposition has been estimated separately for each dominant land use type surrounding each site, and this approach is also recommended for future calculations for easy application of the results to assessments of the mercury effects on various ecosystems.
Preconception syphilis seroprevalence and association with duration of marriage and age among married individuals in Guangdong Province, China: A population-based cross-sectional study

Background Duration of marriage (DoM) and age are important characteristics of married individuals, who are the critical population for eliminating mother-to-child transmission (MTCT) of syphilis. A deep understanding of the preconception syphilis seroprevalence (PSS) and its distribution among this population may be able to help to eliminate MTCT. However, few population-based epidemiological studies have been focused on this group, and the association of DoM and age with PSS remains unclear. Methodology/Principal findings This study used data from 4,826,214 married individuals aged 21–49 years who participated in the National Free Preconception Health Examination Project in Guangdong Province, China, between 2014 and 2019. Syphilis was screened using the rapid plasma reagin (RPR) test. The seroprevalence time series, seroprevalence map, and hot spot analysis (HSA) were employed to visualize the spatiotemporal distribution. The restricted cubic spline (RCS) based on multivariate logistic regression was used to model the association of DoM and age with PSS. The interactions on the additive scale of DoM and age were also assessed. The PSS was 266.61 per 100,000 persons (95% CI: 262.03–271.24) and the burden was higher in economically underdeveloped area within the province. A strong J-shaped non-linearity association was observed between age and PSS. Specifically, the risk of seropositivity was relatively flat until 27 years of age among men and increased rapidly afterwards, with an adjusted odds ratio (aOR) of 1.13 (95% CI: 1.12–1.13) per unit. Among women, the risk of seropositivity was relatively flat until 25 years of age and increased rapidly afterwards with an aOR of 1.08 (95% CI: 1.08–1.09) per unit. DoM was negatively associated with PSS among married individuals. Moreover, the combined effects of age and DoM appeared to be synergistic. Conclusions/Significance Our findings suggest that attention should be paid to preventing syphilis in underdeveloped areas and that syphilis screening in newly married individuals who are in their late 20s or older should be recommended. Additionally, early syphilis prevention strategies should be implemented among young people as early as possible.
Electromagnetic diffraction at skew incidence by a wedge with anisotropic impedance faces

The asymptotic expressions for the total field excited by a plane wave obliquely incident on a wedge with anisotropic impedance faces are represented in the framework of the uniform geometrical theory of diffraction. The problem of decoupling the functional difference equations is solved by applying the perturbation technique on the basis of two analytical solutions: normal incidence and grazing to the edge incidence. The numerical results agree well with those presented in published papers and provide a uniform and continuous behavior of the field dependent upon the skewness of the incident wave outside the wedge region.
The dependence of vircator oscillation mode on cathode material

This paper presents the effects of cathode materials on the oscillation mode of a virtual cathode oscillator (vircator). In the case of the stainless steel cathode, an oscillation mode hopping appeared with two separate frequencies. Interestingly, the vircator using the carbon fiber cathode exhibited an almost unchanged microwave frequency throughout the microwave pulse. To understand this phenomenon, several parameters are compared, including the diode voltage, accelerating gap, emitting area, and beam uniformity. It was found that a flat-top voltage and a relatively stable gap will provide a possibility of generating a constant microwave frequency. Further, the cathode operated in a regime where the beam current was between the space-charge limited current determined by Child–Langmuir law and the bipolar flow. On the cathode surface, the electron emission is initiated from discrete plasma spots and next from a continuing area, while there is a liberation process of multilayer gases on the anode surface.
LITHIUM ABUNDANCES FROM OPTICAL HIGH-RESOLUTION SPECTROSCOPY OF WEAK-LINE T TAURI STARS

We present high-resolution spectroscopic observations for a sample of 19 weak-line T Tauri stars (WTTSs). Based on these observations and data of 108 WTTSs taken from the literature, we derive lithium abundances for 127 WTTSs. Investigation of a possible relation between lithium and rotation in WTTSs shows that: (1) rapidly rotating WTTSs have comparatively lower lithium abundances than their slower rotating counterparts; (2) in the spectral-type range G0–K0, most of the WTTSs share the same Li content irrespective of their Teff; and (3) active late-type binaries do not obey the correlation between lithium abundances and rotation periods, since the tidally locked rotation of the late-type binary system leads naturally to slower lithium destruction rates.
A retrospective study of native wild birds and reptiles admitted to three New Zealand wildlife hospitals due to predation by cats

ABSTRACT Aims To investigate the types of wildlife affected and outcomes of hospitalisation for native wild birds and reptiles admitted to three wildlife hospitals in New Zealand following predation by cats. Methods We reviewed hospital records of three wildlife hospitals (Wildbase Hospital (WBH) in Palmerston North; The Wildlife Hospital – Dunedin (DWH); and The Nest Te Kōhanga (TNTK) in Wellington) for cases of native species with a submission history or diagnosis of predation by cats over the period 2006–2022. Frequency analysis and cross-tabulation of the data were carried out using the factors wildlife hospital, animal order, species, and case outcome. Results Native wildlife (n = 639) presented following predation by cats to the three wildlife hospitals comprised 598 (93.6%) birds from 31 species and 41 (6.4%) reptiles from eight species. The mortality rate of these patients combined was 61.8% (395/639), with the other 38.2% (244/639) being released from hospital to rehabilitation facilities, released to the wild, or, for a small number, put into permanent captive placements. The most common species of birds admitted due to predation by cats were tūī (Prosthemadera novaeseelandiae; n = 173), silvereyes (Zosterops lateralis; n = 142), sacred kingfishers (Todiramphus sanctus; n = 100) and kererū (Hemiphaga novaeseelandiae; n = 70). There was an overall trend to increasing numbers of wildlife admitted for predation by cats over the period of this review, but the different operating periods of the three hospitals should be considered. Each of the three hospitals saw a different mix of species, with Wellington's TNTK seeing the widest diversity of species affected. Conclusions Predation by cats was a common cause of native birds and reptiles being admitted to all three wildlife hospitals and a diversity of urban and rural wildlife were affected. Clinical relevance Predation by cats causes significant mortality in wildlife patients admitted to wildlife hospitals despite best current treatment. Cat management strategies in Aotearoa New Zealand should consider the welfare and health of wildlife.
Local three-dimensional magnetostatic equilibria

An analytic representation of a three-dimensional (3-D) magnetostatic equilibrium that is localized to a magnetic flux surface is introduced. This model, which generalizes prior work for axisymmetric systems, allows one to completely specify the structure of the equilibria through a finite number of 3-D shaping and profile variations. This model can be implemented to study the effects of the equilibrium variations on localized instabilities, such as ballooning modes or microinstabilities.
Super-strong Hydrogel Composites Reinforced with PBO Nanofibers for Cartilage Replacement.

Cartilage replacement materials exhibiting a set of demanding properties such as high water content, high mechanical stiffness, low friction, and excellent biocompatibility are quite difficult to achieve. Here, poly(p-phenylene-2,6-benzobisoxazole) (PBO) nanofibers were combined with polyvinyl alcohol (PVA) to form a super-strong structure with a performance that surpasses the vast majority of previously existing hydrogels. PVA-PBO composites with water contents in the 59-76% range exhibited tensile and compressive moduli reaching 20.3 and 4.5 MPa, respectively, and a coefficient of friction below 0.08. Further, they were biocompatible and supported the viability of chondrocytes for one week, with significant improvements in cell adhesion, proliferation and differentiation compared to PVA. The new composites could be safely sterilized by steam heat or gamma radiation without compromising their integrity and overall performance. In addition, they showed potential to be used as delivery platforms of anti-inflammatory drugs at the local level. These attractive features make PVA-PBO composites highly competitive engineered materials with remarkable potential for use in the design of load-bearing tissues. Complementary work has also revealed that these composites will be interesting alternatives in other industrial fields where high thermal and mechanical resistance are essential requirements, or which can take advantage of the pH responsiveness functionality. This article is protected by copyright. All rights reserved.
Defining patient’s experiential knowledge: Who, what and how patients know. A narrative critical review

Abstract Experiential knowledge is today increasingly valued in health‐care practices, public health policies and health research and education programs. However, despite popular and institutional success, the concept remains loosely defined with the result of weakening its heuristic scope and paving the way for its commodification. In this article, we seek to provide a finer characterisation of patients’ experiential knowledge’s features and specificities through a critical narrative review of humanities and social science (HSS) literature published in English and French (1976–2021). Inspired by Jovchelovitch’s analysis of social knowledge, we seek to highlight the diversity and plurality of forms and articulations of knowledge that characterise experiential knowledge, as well as the gradual, dynamic and entangled process that leads from experience to knowledge and expertise. Our analysis points to the need for future research to adopt a resolutely pragmatic and situated orientation in the study of experiential knowledge and the new figures of the contemporary patient that they help to create.
Membrane-Active Cyclic Amphiphilic Peptides: Broad-Spectrum Antibacterial Activity Alone and in Combination with Antibiotics

We designed a library of 24 cyclic peptides containing arginine (R) and tryptophan (W) residues in a sequential manner [RnWn] (n = 2–7) to study the impact of the hydrophilic/hydrophobic ratio, charge, and ring size on the antibacterial activity against Gram-positive and Gram-negative strains. Among peptides, 5a and 6a demonstrated the highest antimicrobial activity. In combination with 11 commercially available antibiotics, 5a and 6a showed remarkable synergism against a large panel of resistant pathogens. Hemolysis (HC50 = 340 μg/mL) and cell viability against mammalian cells demonstrated the selective lethal action of 5a against bacteria over mammalian cells. Calcein dye leakage and scanning electron microscopy studies revealed the membranolytic effect of 5a. Moreover, the stability in human plasma (t1/2 = 3 h) and the negligible ability of pathogens to develop resistance further reflect the potential of 5a for further development as a peptide-based antibiotic.
Deciphering the “obesity paradox” in the elderly: A systematic review and meta‐analysis of sarcopenic obesity

Aging and obesity are two global concerns in public health. Sarcopenic obesity (SO), defined as the combination of age‐related sarcopenia and obesity, has become a pressing issue. This systematic review and meta‐analysis summarize the current clinical evidence relevant to SO. PubMed, Embase, and Web of Science were searched, and 106 clinical studies with 167,151 elderlies were included. The estimated prevalence of SO was 9% in both men and women. Obesity was associated with 34% reduced risk of sarcopenia (odds ratio [OR] 0.66, 95% CI 0.48–0.91; p < 0.001). The pooled hazard ratio (HR) of all‐cause mortality was 1.51 (95% CI 1.14–2.02; p < 0.001) for people with SO compared with healthy individuals. SO was associated with increased risk of cardiovascular disease and related mortality, metabolic disorders, cognitive impairment, arthritis, functional limitation, and lung diseases (all ORs > 1.0, p < 0.05). The attenuated risk of sarcopenia in elderlies with obesity (“obesity paradox”) was dependent on higher muscle mass and strength. Apart from unifying the diagnosis of SO, more research is needed to subphenotype people with obesity and sarcopenia for individualized treatment. Meanwhile, the maintenance of proper body composition of muscle and fat may delay or attenuate the adverse outcomes of aging.
Quantum coherent energy transport in the Fenna–Matthews–Olson complex at low temperature

Significance We use ultrafast two-dimensional optical spectroscopy to study the primary steps in the energy transport in photosynthesis using the Fenna–Matthews–Olson complex as a model. By varying temperature to modify the intensity of decohering fluctuations, we determine the onset of quantum coherence effects at an ultralow temperature of 20 K. A theoretical analysis shows that this electronic quantum coherence can be separated from the pronounced vibrational coherences accompanying energy transport. We provide a complete picture of the lifetimes of electronic and vibrational quantum coherences and show that energy transport occurs under strong system–bath interactions. Electronic coherence can in principle sustain energy transfer at 20 K but rapidly fades away with increasing temperatures, becoming irrelevant under physiological conditions.
Understanding CDC’s Vaccine Communication during the COVID-19 Pandemic and Its Effectiveness in Promoting Positive Attitudes toward the COVID-19 Vaccine

ABSTRACT The COVID-19 pandemic has imposed many communication challenges for public health authorities, especially communicating the safety, effectiveness, and importance of the COVID-19 vaccine. This study takes an integrative approach that includes a content analysis of COVID-19 vaccine-related messages from the CDC Facebook page and an experimental test of the effectiveness of the same types of vaccine-related messages on participants’ attitudes toward the COVID-19 vaccine. Our findings from the content analysis show that gain-frame was used significantly more than loss-frame, and statistical evidence was more prevalent than narrative evidence in the CDC’s COVID-19 vaccine-related messaging. Results from the experiment indicated that loss-framed, and messages with statistical evidence, may be more successful in promoting positive attitudes toward the COVID-19 vaccine.
Genetic liability to suicidal thoughts and behaviors and risk of suicide attempt in US military veterans: moderating effects of cumulative trauma burden

Abstract Background Little is known about environmental factors that may influence associations between genetic liability to suicidality and suicidal behavior. Methods This study examined whether a suicidality polygenic risk score (PRS) derived from a large genome-wide association study (N = 122,935) was associated with suicide attempts in a population-based sample of European-American US military veterans (N = 1664; 92.5% male), and whether cumulative lifetime trauma exposure moderated this association. Results Eighty-five veterans (weighted 6.3%) reported a history of suicide attempt. After adjusting for sociodemographic and psychiatric characteristics, suicidality PRS was associated with lifetime suicide attempt (odds ratio 2.65; 95% CI 1.37–5.11). A significant suicidality PRS-by-trauma exposure interaction emerged, such that veterans with higher levels of suicidality PRS and greater trauma burden had the highest probability of lifetime suicide attempt (16.6%), whereas the probability of attempts was substantially lower among those with high suicidality PRS and low trauma exposure (1.4%). The PRS-by-trauma interaction effect was enriched for genes implicated in cellular and developmental processes, and nervous system development, with variants annotated to the DAB2 and SPNS2 genes, which are implicated in inflammatory processes. Drug repurposing analyses revealed upregulation of suicide gene-sets in the context of medrysone, a drug targeting chronic inflammation, and clofibrate, a triacylglyceride level lowering agent. Conclusion Results suggest that genetic liability to suicidality is associated with increased risk of suicide attempt among veterans, particularly in the presence of high levels of cumulative trauma exposure. Additional research is warranted to investigate whether incorporation of genomic information may improve suicide prediction models.
Predicting serotonin toxicity in serotonin reuptake inhibitor overdose

Abstract Aims We aimed to investigate the frequency of serotonin toxicity following overdose of antidepressants that inhibit serotonin reuptake and the factors that influence the probability of serotonin toxicity occurring. Methods This was a retrospective cohort study of overdoses that included selective serotonin reuptake inhibitors (SSRIs) (70%) and serotonin norepinephrine reuptake inhibitors (SNRIs) (30%) admitted to a tertiary toxicology unit over 23 years. A multivariate mixed effects logistic regression model using NONMEM (7.2.0) was used to determine factors that influenced the probability of serotonin toxicity occurring. Results There were 1978 overdoses in 1520 patients; median age 33 y (range: 13–86 years) and 64% female. Median defined daily dose equivalent (DDD) was 15 (1–420). Co-ingestants were taken in 1678/1978 (85%) overdoses: 11 co-ingested the monoamine oxidase-A inhibitor (MAOI) moclobemide, 99 (5%) co-ingested olanzapine, 58 (3%) co-ingested risperidone and 417 co-ingested a benzodiazepine (21%). Serotonin toxicity occurred in 269 overdoses (13.6%). The probability of serotonin toxicity increased slightly per 10 DDD units dose [OR, 1.01; 95% confidence intervals (CIs): 0.93–1.10], increased for an SNRI vs. an SSRI [OR, 1.07; 95% CI: 0.99–1.15], and markedly increased with co-ingestion of moclobemide [OR, 33.12; 95% CI: 7.5–147]. The probability decreased per 10 y age [OR, 0.84; 95% CI: 0.74–0.95], and with co-ingestion of the serotonin 2 A receptor (5-HT2A) antagonists olanzapine [OR, 0.40; 95% CI: 0.17–0.94] or risperidone [OR, 0.13; 95% CI: 0.02–0.99]. The probability of serotonin toxicity was 12.5% at 1 DDD (therapeutic), 12.7% at 15 DDDs and 19% at 420 DDDs. In overdoses of the median dose of 15 DDDs, co-ingestion of moclobemide increased the probability to 83%, and co-ingestion of olanzapine or risperidone decreased it to 5.5% and 1.8%, respectively. Conclusions Serotonin toxicity is common following SSRI/SNRI overdose. Although dose increases probability, this was only a small effect. Co-ingestion with olanzapine or risperidone reduced the risk 2–6-fold, and moclobemide increased the risk 5-fold.