Miracle-dz/UniFAR-FTUs huggingface dataset:
Hidden Mass in the Asteroid Belt

Abstract The total mass of the asteroid belt is estimated from an analysis of the motions of the major planets by processing high precision measurements of ranging to the landers Viking-1, Viking-2, and Pathfinder (1976–1997). Modeling of the perturbing accelerations of the major planets accounts for individual contributions of 300 minor planets; the total contribution of all remaining small asteroids is modeled as an acceleration caused by a solid ring in the ecliptic plane. Mass M ring of the ring and its radius R are considered as solve-for parameters. Masses of the 300 perturbing asteroids have been derived from their published radii based mainly on measured fluxes of radiation, making use of the corresponding densities. This set of asteroids is grouped into three classes in accordance with physical properties and then corrections to the mean density for each class are estimated in the process of treating the observations. In this way an improved system of masses of the perturbing asteroids has been derived. The estimate M ring ≈(5±1)×10 −10 M ⊙ is obtained ( M ⊙ is the solar mass) whose value is about one mass of Ceres. For the mean radius of the ring we have R ≈2.80 AU with 3% uncertainty. Then the total mass M belt of the main asteroid belt (including the 300 asteroids mentioned above) may be derived: M belt ≈(18±2)×10 −10 M ⊙ . The value M belt includes masses of the asteroids which are already discovered, and the total mass of a large number of small asteroids—most of which cannot be observed from the Earth. The second component M ring is the hidden mass in the asteroid belt as evaluated from its dynamical impact onto the motion of the major planets. Two parameters of a theoretical distribution of the number of asteroids over their masses are evaluated by fitting to the improved set of masses of the 300 asteroids (assuming that there is no observational selection effect in this set). This distribution is extrapolated to the whole interval of asteroid masses and as a result the independent estimate M belt ≈18×10 −10 M ⊙ is obtained which is in excellent agreement with the dynamical finding given above. These results make it possible to predict the total number of minor planets in any unit interval of absolute magnitude H . Such predictions are compared with the observed distribution; the comparison shows that at present only about 10% of the asteroids with absolute magnitude H
Mitoguardin2 Is Associated With Hyperandrogenism and Regulates Steroidogenesis in Human Ovarian Granulosa Cells

Abstract Polycystic ovary syndrome (PCOS) is an endocrinopathy characterized by hyperandrogenism, anovulation, and polycystic ovaries, in which hyperandrogenism manifests by excess androgen and other steroid hormone abnormalities. Mitochondrial fusion is essential in steroidogenesis, while the role of mitochondrial fusion in granulosa cells of hyperandrogenic PCOS patients remains unclear. In this study, mRNA expression of mitochondrial fusion genes mitoguardin1, −2 (MIGA 1, −2) was significantly increased in granulosa cells of hyperandrogenic PCOS but not PCOS with normal androgen levels, their mRNA expression positively correlated with testosterone levels. Dihydrotestosterone (DHT) treatment in mice led to high expression of MIGA2 in granulosa cells of ovulating follicles. Testosterone or forskolin/ phorbol 12-myristate 13-acetate treatments increased expression of MIGA2 and the steroidogenic acute regulatory protein (StAR) in KGN cells. MIGA2 interacted with StAR and induced StAR localization on mitochondria. Furthermore, MIGA2 overexpression significantly increased cAMP-activated protein kinase A (PKA) and phosphorylation of AMP-activated protein kinase (pAMPK) at T172 but inhibited StAR protein expression. However, MIGA2 overexpression increased CYP11A1, HSD3B2, and CYP19A1 mRNA expression. As a result, MIGA2 overexpression decreased progesterone but increased estradiol synthesis. Besides the androgen receptor, testosterone or DHT might also regulate MIGA2 and pAMPK (T172) through LH/choriogonadotropin receptor-mediated PKA signaling. Taken together, these findings indicate that testosterone regulates MIGA2 via PKA/AMP-activated protein kinase signaling in ovarian granulosa cells. It is suggested mitochondrial fusion in ovarian granulosa cells is associated with hyperandrogenism and potentially leads to abnormal steroidogenesis in PCOS.
Esophageal Stab Wounds Repaired Endoscopically: A Case Report and Comprehensive Literature Review

Esophageal injuries are typically iatrogenic after endoscopic/surgical procedures, but they are rarely caused by penetrative or blunt trauma. We present a case of patient who suffered multiple stab wounds to the neck and underwent surgical repair for hemorrhagic shock but was ultimately diagnosed and treated successfully via endoscopy for a thoracic esophageal injury. Early detection is imperative and usually diagnosed via contrast studies but less commonly via direct visualization endoscopically. Moreover, endoscopic treatment is also less commonly utilized, even if diagnosed from that modality. Cervical injuries also confer a lower mortality than thoracic injuries.
Recursive subdivision and hypergeometric functions

We describe a method for efficient calculation of coefficients for subdivision schemes. We work on the unit sphere and we express the z-coordinate of all the existing points as power series in the variable cos /spl theta/. Any linear combination of them is also a power series in cos /spl theta/ and, by solving a linear system, we determine the linear combination that will give the smoothest interpolation of the sphere at a particular point.
Disrupting the Mood and Obesity Cycle: The Potential Role of Metformin

Mounting evidence links obesity, metabolic dysfunction, mood, and cognition. Compromised metabolic health and psychological functioning worsen clinical outcomes, diminish quality of life, and contribute to comorbid conditions. As a medication with both insulin-sensitizing and anti-inflammatory effects, metformin affords the exciting opportunity to abrogate the bidirectional relationship between poor metabolic health and psychological function. In the current paper, we review the literature linking metformin to mood and cognitive function, examine potential underlying mechanisms, and suggest new directions for investigating the role of metformin in increasing adherence to health behavior recommendations.
The Violent Interstellar Medium

Observational evidence for high-velocity and high-temperature interstellar gas is reviewed. The physical processes that characterize this gas are described, including the ionization and emissivity of coronal gas, the behavior and appearance of high-velocity shocks, and interfaces between coronal gas and cooler interstellar gas. Hydrodynamical models for the action of supernova explosions and stellar winds on the interstellar medium are examined, and recent attempts to synthesize all the processes considered into a global model for the interstellar medium are discussed.
Prevalence, antibiotic resistance patterns, and biofilm formation ability of Enterobacterales recovered from food of animal origin in Egypt

Background and Aim: The majority of animal-derived food safety studies have focused on foodborne zoonotic agents; however, members of the opportunistic Enterobacteriaceae (Ops) family are increasingly implicated in foodborne and public health crises due to their robust evolution of acquiring antimicrobial resistance and biofilms, consequently require thorough characterization, particularly in the Egyptian food sector. Therefore, this study aimed to determine the distribution and prevalence of Enterobacteriaceae family members in animal-derived foods, as well as their resistance to important antimicrobials and biofilm-forming potential. Materials and Methods: A total of 274 beef, rabbit meat, chicken meat, egg, butter, and milk samples were investigated for the presence of Enterobacteriaceae. All isolated strains were first recognized using traditional microbiological techniques. Following that, matrix-assisted laser desorption ionization-time of flight mass spectrometry was used to validate the Enterobacteriaceae’s identity. The isolated enterobacteria strains were tested on disk diffusion and crystal violet quantitative microtiter plates to determine their antibiotic resistance and capacity to form biofilms. Results: There have been thirty isolates of Enterobacteriaceae from seven different species and four genera. Out of the three food types, Pseudomonas aeruginosa had the highest prevalence rate (4.1%). With three species, Enterobacter genera had the second-highest prevalence (3.28%) across five different food categories. In four different food types, the Klebsiella genera had the second-highest distribution and third-highest incidence (2.55%). Almost all isolates, except three Proteus mirabilis, showed prominent levels of resistance, particularly to beta-lactam antibiotics. Except for two Enterobacter cloacae and three P. mirabilis isolates, all isolates were classified as multidrug-resistant (MDR) orextensively multidrug-resistant (XDR). The multiple antibiotic resistance index (MARI) of the majority of isolates dropped between 0.273 and 0.727. The highest MARI was conferred by Klebsiella pneumoniae, at 0.727. Overall, 83.33% of the isolates had strong biofilm capacity, while only 16.67% exhibited moderate capacity. Conclusion: The MDR, XDR, and strong biofilm indicators confirmed in 83.33% of the currently tested Enterobacteriaceae from animal-derived foods suggest that, if not addressed, there may be rising risks to Egypt’s economy and public health.
Predicting Habitual Use of Wearable Health Devices Among Middle-aged Individuals With Metabolic Syndrome Risk Factors in South Korea: Cross-sectional Study

Background Prevention of the risk factors for metabolic syndrome (MetS) in middle-aged individuals is an important public health issue. Technology-mediated interventions, such as wearable health devices, can aid in lifestyle modification, but they require habitual use to sustain healthy behavior. However, the underlying mechanisms and predictors of habitual use of wearable health devices among middle-aged individuals remain unclear. Objective We investigated the predictors of habitual use of wearable health devices among middle-aged individuals with risk factors for MetS. Methods We proposed a combined theoretical model based on the health belief model, the Unified Technology of Acceptance and Use of Technology 2, and perceived risk. We conducted a web-based survey of 300 middle-aged individuals with MetS between September 3 and 7, 2021. We validated the model using structural equation modeling. Results The model explained 86.6% of the variance in the habitual use of wearable health devices. The goodness-of-fit indices revealed that the proposed model has a desirable fit with the data. Performance expectancy was the core variable explaining the habitual use of wearable devices. The direct effect of the performance expectancy on habitual use of wearable devices was greater (β=.537, P<.001) than that of intention to continue use (β=.439, P<.001), and the total effect estimate of the performance expectancy was 0.909 (P<.001), including the indirect effect (β=.372, P=.03) on habitual use of wearable devices via intention to continue use. Furthermore, performance expectancy was influenced by health motivation (β=.497, P<.001), effort expectancy (β=.558, P<.001), and risk perception (β=.137, P=.02). Perceived vulnerability (β=.562, P<.001) and perceived severity (β=.243, P=.008) contributed to health motivation. Conclusions The results suggest the importance of the users’ performance expectations for wearable health devices for the intention of continued use for self-health management and habituation. Based on our results, developers and health care practitioners should find better ways to meet the performance expectations of middle-aged individuals with MetS risk factors. They also should generate device use easier and find a way to encourage users’ health motivation, thereby reducing users’ effort expectancy and resulting in a reasonable performance expectancy of the wearable health device, to induce users’ habitual use behaviors.
On the Causes of Effects

We welcome Professor Pearl’s comment on our original article, Dawid et al. Our focus there on the distinction between the “Effects of Causes” (EoC) and the “Causes of Effects” (CoE) concerned two fundamental problems, one a theoretical challenge in statistics and the other a practical challenge for trial courts. In this response, we seek to accomplish several things. First, using Pearl’s own notation, we attempt to clarify the similarities and differences between his technical approach and that in Dawid et al. Second, we consider the more practical challenges for CoE in the trial court setting, and explain why we believe Pearl’s analyses, as described via his example, fail to address these. Finally, we offer some concluding remarks.
Cardiomyopathy and Sudden Cardiac Death Among the Athletes in Developing Countries: Incidence and Their Prevention Strategies

The incidence of cardiomyopathy in athletes contributes significantly to the public health burden in developing countries. Most effective management strategies primarily rely on the modification of risk factors, and it is less expensive compared to other advanced investigations. Moreover, limited data is available concerning the incidence of adverse events including cardiac arrest and the strategies to prevent them, especially in this population subset. Therefore, devising preventative strategies that can easily be implemented in athletes and provide a cost-effective approach is warranted. We aim to discuss the incidence of major adverse cardiac events in athletes with cardiomyopathies and their associated risk factors and to evaluate the various strategies proposed to prevent the progression of cardiomyopathy in this population, with the initial hypothesis that the treatment of these pathologies poses a substantial challenge in this population. With regard to methodology, this is a narrative review. Search terms were described using the Population, Exposure, and Outcome (PEO) framework. A comprehensive search strategy was used to screen and identify any relevant literature in the PubMed and Google Scholar databases. This was done in accordance with the Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) protocol. Four studies were identified in the final analysis. The incidence of sudden cardiac arrest varied between 0.3% and 0.33% among the athletes affected with cardiomyopathies. Routine and pre-participation screening has shown success in reducing the incidence of sudden cardiac death in athletes as a result of undiagnosed cardiomyopathies. Supervised exercise regimes have been proposed to reduce the incidence of cardiomyopathy in athletes. Beyond identification strategies, the prevention of cardiomyopathies revolves around the modification of risk factors. To conclude, the challenges athletes face, suffering from cardiomyopathy, have been an ongoing issue with unexpected cardiac arrest as the end result. Despite the decreased incidence of cardiomyopathies observed in athletes, the challenge in diagnosis can result in catastrophic outcomes, especially in developing countries. Therefore, adopting prevention strategies can have a profound impact on the identification and management of these pathologies.
Lessons Learned from Atomic Oxygen Interaction with Spacecraft Materials in Low Earth Orbit

There have been five Materials International Space Station Experiment (MISSE) passive experiment carriers (PECs) (MISSE 1–5) to date which have been launched, exposed in space on the exterior of International Space Station (ISS) and then returned to Earth for analysis. An additional four MISSE PECs (MISSE 6A, 6B, 7A & 7B) are in various stages of completion. The PECs are two‐sided suitcase size sample carriers that are intended to provide information on the effects of the low Earth orbital environment on a wide variety of materials and components. As a result of post retrieval analyses of the retrieved MISSE 2 experiments and numerous prior space experiments, there have been valuable lessons learned and needs identified that are worthy of being documented so that planning, design, and analysis of future space environment experiments can benefit from the experience in order to maximize the knowledge gained. Some of the lessons learned involve the techniques, concepts, and issues associated with measuring a.
Is the Cromwell current driven by equatorial Rossby waves?

A second-order theory for equatorial, baroclinic Rossby waves in a bounded ocean yields, among other components, terms of zero frequency. We inquire whether the associated rectified flow (or ‘streaming’, or ‘mass transport’) can be related to the submerged equatorial jet observed by Cromwell, Knauss and others. For quite reasonable models of baroclinic Rossby waves, the resultant streaming can be sharply concentrated at the equator, and varies in depth as N(z), thus giving maximum flow at the thermocline (where the Väisälä frequency N(z) is largest). In this way the rectification hypothesis might account for the observed submerged equatorial steering of the Cromwell current. The observed direction of streaming calls for a predominance of equatorially symmetric Rossby waves. The observed magnitude implies that the r.m.s. fluctuations be of the same order as the mean current; that is to say, we have applied weakinteraction theory to a strong-interaction problem. There are other difficulties.
Artemisia abrotanum and Symphytum officinale Polyphenolic Compounds-Rich Extracts with Potential Application in Diabetes Management

Lately, there has been increased interest in the development of phytochemical alternatives for the prevention and treatment of type 2 diabetes, the alternatives that are able to reduce or prevent glucose absorption by inhibiting digestive enzymes. In this context, this study aims to analyze the inhibitory α-amylase and α-glucosidase activities of Artemisia abrotanum and Symphytum officinale polyphenolic compound-rich extracts obtained by membrane technologies (micro- and ultrafiltration). Polyphenols and flavones content, HPLC-MS polyphenolic compounds profiling, antioxidant activity, and cytotoxic potential of these herbs were determined. Major phenolic acid compounds were chlorogenic acid, ellagic acid, caffeic acid, and rosmarinic acid. The flavone content was higher in the case of A. abrotanum extracts, and the major compounds were rutin and umbelliferone. The polyphenolic-rich extract of A. abrotanum had the highest quantities of polyphenols, 977.75 µg/mL, and flavones, 552.85 µg/mL, as well as a pronounced α-amylase inhibitory activity (IC50 1881.21 ± 1.8 mg/mL), a value close to acarbose inhibitory activity (IC50 1110.25 ± 8.82 mg/mL) that was used as the control for both enzymes. The α-glucosidase inhibitory activity was higher for both herb extracts, more pronounced for S. officinale polyphenolic-rich extract (IC50 291.56 ± 2.1 mg/mL), a value higher than that of acarbose (IC50 372.35 ± 3.2 mg/mL). These plants show potential as a complementary therapy for type 2 diabetes management.
Molecular Changes in Cells of Patients with Type 2 Diabetes Mellitus Depending on Changes in Glycemia Level in the Context of Lifestyle—An Overview of the Latest Scientific Discoveries

Diabetes mellitus is a significant health problem for medicine and economics. In 80–90% of cases, it is type 2 diabetes (T2DM). An essential aspect for people with T2DM is to control blood glucose levels and avoid significant deviations. Modifiable and non-modifiable factors influence the incidence of hyperglycemia and, sometimes, hypoglycemia. The lifestyle modifiable factors are body mass, smoking, physical activity, and diet. These affect the level of glycemia and impact molecular changes. Molecular changes affect the cell’s primary function, and understanding them will improve our understanding of T2DM. These changes may become a therapeutic target for future therapy of type 2 diabetes, contributing to increasing the effectiveness of treatment. In addition, the influence of external factors (e.g., activity, diet) on each domain of molecular characterization has gained importance towards a better understanding of their role in prevention. In the current review, we aimed to collect scientific reports on the latest research about modifiable factors connected with the style of life which affect the glycemic level in the context of molecular discoveries.
1.3-/spl mu/m polarization-insensitive optical amplifier structure based on coupled quantum wells

We show that polarization-insensitive optical gain over a wide bandwidth can be realized in a coupled pseudomorphic multiple-quantum-well structure. The barrier width is chosen such that heavy-hole subbands are grouped tightly and light-hole subbands are widely separated in energy. For specific strain conditions, the uppermost valence subbands, which have large occupation probability and strongly contribute to the gain, consist of a single light-hole subband and a group of coupled heavy-hole subbands. This arrangement gives rise to balanced gains for the TE and TM polarizations. We present calculated results for 1.3-/spl mu/m semiconductor optical amplifier structures based on bands calculated in the framework of an eight-band k/spl middot/p model. Two different material systems are examined, InAlGaAs and GaInAsP, on InP substrates.
Large-Scale Structures and Growth of a Flat Plate Compressible Wake

Experiments conducted on a flat plate wake in a compressible flow at Mach 2 are described. Large-scale organized motions are revealed both in the separating boundary layer upstream and in the wake downstream. The organized motions in the wake contained within them embeded vortex structures, whose periodicity was found to be weak. The broadband spectra contained a distinct frequency with a Strouhal number of 0.3. The study of mean flow characteristics showed that some qualitative similarity exists in the near- and intermediate-wake regions. The relative Mach number distribution showed the compressibility effects to be small
Attenuation and cross-polarization measurements at 20 GHz using the ATS-6 satellite with simultaneous radar observations

Measurements of cross polarization using the 20-GHz beacon on the NASA-ATS6 satellite as received at a groundstation on Oxenhope Moor, Yorkshire, U. K. are reported. A co-sited range-gated radar was used to locate hydrometeors causing cross polarization. High cross polarization was frequently measured with little rainfall on the satellite radio path. Radar evidence shows that such "anomalous" cross polarization is associated with high-altitude particles well above the radar bright band. A pronounced correlation between atmospheric electricity, as measured with a point-discharge current probe and cross polarization is reported. In addition, abrupt changes in cross polarization were seen, coincident with lightning strokes. These results are interpreted in terms of scattering from ice needles lying in the horizontal plane and suffering orientation under the influence of static electric fields.
Regularized magnetic islands. II. The role of polarization current

The role of polarization current in the problem of rotating magnetic islands in the absence of drift effects is discussed for the case of nonregularized and regularized velocity profiles governed by the perpendicular viscosity. The polarization current is calculated taking into account the finite ion Larmor radius effects. It is shown that, in correspondence with the general rule by Waelbroeck and Fitzpatrick [Phys. Rev. Lett. 78, 1703 (1997)], this current is destabilizing. The destabilizing contribution of the polarization current into the generalized Rutherford equation for the magnetic island width does not depend on whether the profile function is regularized or not. It is shown that the Larmor corrections to the current consist of the sum of two oppositely directed currents and do not contribute into the generalized Rutherford equation.