Miracle-dz/UniFAR-FTUs huggingface dataset:
Controls of the Foreland Deformation Pattern in the Orogen‐Foreland Shortening System: Constraints From High‐Resolution Geodynamic Models

Controls on the deformation pattern (shortening mode and tectonic style) of orogenic forelands during lithospheric shortening remain poorly understood. Here, we use high‐resolution 2D thermomechanical models to demonstrate that orogenic crustal thickness and foreland lithospheric thickness significantly control the shortening mode in the foreland. Pure‐shear shortening occurs when the orogenic crust is not thicker than the foreland crust or thick, but the foreland lithosphere is thin (<70–80 km, as in the Puna foreland case). Conversely, simple‐shear shortening, characterized by foreland underthrusting beneath the orogen, arises when the orogenic crust is much thicker. This thickened crust results in high gravitational potential energy in the orogen, which triggers the migration of deformation to the foreland under further shortening. Our models present fully thick‐skinned, fully thin‐skinned, and intermediate tectonic styles in the foreland. The first tectonics forms in a pure‐shear shortening mode whereas the others require a simple‐shear mode and the presence of thick (>∼4 km) sediments that are mechanically weak (friction coefficient <∼0.05) or weakened rapidly during deformation. The formation of fully thin‐skinned tectonics in thick and weak foreland sediments, as in the Subandean Ranges, requires the strength of the orogenic upper lithosphere to be less than one‐third as strong as that of the foreland upper lithosphere. Our models successfully reproduce foreland deformation patterns in the Central and Southern Andes and the Laramide province.
The defence performance measurement framework: measuring the performance of defence organisations at the strategic level

ABSTRACT As the gap between strategic commitments and budgetary constraints continues to grow, defence organisations have introduced performance management initiatives to support decision-making and to improve governance. However, introducing managerial practices in public organisations, including defence, proves to be challenging. As performance management initiatives within defence suffer from an implementation gap, strategic benefits are not being harnessed. In our study, we first exploit the results of a systematic literature review to better anchor the encountered challenges within the literature. We then apply thematic analysis to a unique dataset from twelve NATO countries to propose a new defence-specific performance management framework for the strategic level. As the framework preserves the benefits of existing initiatives while mitigating most recorded challenges, it is proposed as a new guide for designing and assessing defence performance management efforts. Thereby, professionals and scholars are provided with a powerful instrument to address the implementation gap. Moreover, the theoretical and empirical lens adopted facilitates alignment between performance management initiatives, defence policy, defence strategy, and strategic objectives. Notably, policy goals and strategic “ends” are clearly connected to critical processes and resources. Thereby, the proposed framework better supports discussions with key defence stakeholders pertaining to the gap between commitments and constraints.
The Correlation of Regional Stage Exam (UTB) and Progress Test (PT) to Grade Point Average (GPA) of Medical Students at Faculty of Medicine, Universitas Islam Indonesia

Background A regional stage exam, called Ujian Tahap Bersama (UTB) and Progress Test (PT) are formative assessments. UTB II is tested on 4 year medical students to measure their knowledge of pathomechanism to therapy. The PT has been implemented in Faculty of Medicine (FoM), Universitas Islam Indonesia (UII) since 2012. This study aims to determine correlations of UTB and PT to GPA of undergraduate medical students in the FoM UII. Method This study was an observational analytical research with a cross-sectional approach. An analysis of 324 students was conducted. A linear regression analysis was conducted on scores of UTB II (4 year students) and PT (4 year students) correlated to GPA scores of 176 students (student batch of 2015) and 159 students (student batch of 2016). Exclusion criteria of subjects of this study were students who did not follow either one or both of these formative assessments. There were 11 students excluded from the analysis of this study. Result: The data normality test showed a P value of 0.494. Value regression data of the UBT II to the GPA indicated a significant result with a P value of 0.000. Value regression data of the 4 PT to the GPA indicated a significant result with a P value of 0.000. An R square value was 0.464. These results found that the UTB II and 4 PT scores correlated with moderate correlation strength. Conclusion: The UTB II and 4 PT correlated with achievements of cognitive competencies of the medical students. A relationship test of UTB I, II, and III is required. A progress test of PT needs to be conducted annually.
Examining Antecedents on Chinese Customer Loyalty in the Boutique Hotel Business

ABSTRACT Recent developments in the hotel business have caused renewed interest in a new category, the boutique hotel, as a means of attempting a new growth stage. It is important to determine a study about relationship marketing in the boutique hotel context. So, this study aims to investigate the effect of perceived value and customer loyalty, and identify the mediating effects of trust and satisfaction between perceived value and customer loyalty in boutique hotels. By using a quantitative approach, this study collected the data from 400 customers in boutique hotels using a structured questionnaire. The results showed that perceived value had no direct influence on customer loyalty, but it indirectly affected customer loyalty mediated by trust and satisfaction in boutique hotels. At present, relationship marketing issue is a significant concept to support business achievement. This study helps academicians understand how the factors affect customer loyalty in the hospitality field, focusing on the boutique hotel business. For managerial implications, marketers can create great strategies to create customer loyalty toward the hotel business based on an increase in perceived value, trust, and satisfaction. Limitations and directions for future study are also addressed.
Railgun: managing large streaming windows under MAD requirements

Some mission critical systems, e.g., fraud detection, require accurate, real-time metrics over long time sliding windows on applications that demand high throughput and low latencies. As these applications need to run 'forever' and cope with large, spiky data loads, they further require to be run in a distributed setting. We are unaware of any streaming system that provides all those properties. Instead, existing systems take large simplifications, such as implementing sliding windows as a fixed set of overlapping windows, jeopardizing metric accuracy (violating regulatory rules) or latency (breaching service agreements). In this paper, we propose Railgun, a fault-tolerant, elastic, and distributed streaming system supporting real-time sliding windows for scenarios requiring high loads and millisecond-level latencies. We benchmarked an initial prototype of Railgun using real data, showing significant lower latency than Flink and low memory usage independent of window size. Further, we show that Railgun scales nearly linearly, respecting our msec-level latencies at high percentiles (<250ms @ 99.9%) even under a load of 1 million events per second.
BANDUNG

Husein Sastranegara Airport which can be located at the heart of Bandung city nowadays has a runway with its PCN classification fixed at 50 F/C/X/T or equals to a total flexible type pavement thickness precisely on 740 mm. Nevertheless, Boeing 737-800 defines its classification at maximum state up to 51 on ACN scale. Therefore, overlay act upon runway pavement needs to be studied in order to enhance its classification. ACN/PCN is one of ICAO renowned method to determine pavement thickness, while recently FAA has developed a cutting-edge method by using a computerized program called FAARFIELD (FAA Rigid Flexible Iterative Elastic Layer Design). In accordance with the earlier issues, ICAO method analyzes the need of 1041.4 mm pavement thickness for graphical technique and 940.6 mm for analytical technique, while FAARFIELD should only require 840.8 mm pavement thickness in determining its flexible type runway due to the previous overlay act. The presented results of both methods established that runway pavement of Husein Sastranegara Airport shall be improved by an overlay layer immediately
An efficient physical-based method for predicting the long-term evolution of vertical railway track geometries

The dynamic wheel-rail contact forces resulting from the interaction between vehicle and track are responsible for the local track settlement. If these local settlements vary along the track, geometric irregularities develop further amplifying the dynamic loading of the track caused by the interaction between the vehicle and track. In this work, an efficient vehicle-track interaction (VTI) model is presented for predicting the long-term evolution of vertical track settlement during operation. The VTI model has two interacting components – vehicle and track. The vehicle model describes the vertical dynamics of an 8th of a car. The track model considers an elastic rail on discrete (sleeper) supports. Each sleeper location can have its own stiffness, relative height and settlement characteristics. Dependent on the distribution of stiffness and settlement behaviour along the track together with the initial track geometry, each sleeper settles dependent on the number of load cycles (vehicle passes). The track model is initialized with measured vertical track geometry data and static track deflection data at the beginning (day 0) for two types of track sections in the field, a track section where concrete sleepers with Under Sleeper Pads (USP) are used and a track section where only concrete sleepers are used. Using the same settlement model parameters (constant along the track) for the two tracks, the physical-based VTI model can predict the different track geometry quality evolution for both tracks over 350 days. Finally, the VTI model is used to assess the track geometry deterioration when the track/vehicle properties are changed. The prediction strength of the fast VTI model based on the physical understanding can assist in designing and optimizing tracks and in supporting of maintenance activities.
Short-Term Aerobic Exercise Did Not Change Telomere Length While It Reduced Testosterone Levels and Obesity Indexes in PCOS: A Randomized Controlled Clinical Trial Study

Metabolic and hormonal outcomes of polycystic ovary syndrome (PCOS) have implications on telomere biology and physical activity may prevent telomere erosion. We sought to observe the effects of continuous (CAT) and intermittent (IAT) aerobic training on telomere length, inflammatory biomarkers, and its correlation with metabolic, hormonal, and anthropometric parameters of PCOS. This randomized controlled clinical trial study included 87 PCOS randomly stratified according to body mass index (BMI) in CAT (n = 28), IAT (n = 29) and non-training control group (CG, n = 30). The exercises were carried out on a treadmill, three times per week for 16 weeks. The participants’ anthropometric characteristics and biochemical and hormonal concentrations were measured before and after aerobic training or observation period, as the telomere length that was evaluated using quantitative real-time PCR. Four months of aerobic exercises (CAT or IAT) did not alter telomere length and inflammatory biomarkers in PCOS women. Obesity index as BMI and waist circumference (WC), and inflammatory biomarkers negatively affect telomeres. The hyper-andro-genism measured by testosterone levels was reduced after both exercises (CAT, p ≤ 0.001; IAT, p = 0.019). In particular, the CAT reduced WC (p = 0.045), hip circumference (p = 0.032), serum cholesterol (p ≤ 0.001), and low-density lipoprotein (p = 0.030). Whereas, the IAT decreased WC (p = 0.014), waist-to-hip ratio (p = 0.012), free androgen index (FAI) (p = 0.037). WC (p = 0.049) and body fat (p = 0.015) increased in the non-training group while total cholesterol was reduced (p = 0.010). Booth exercises reduced obesity indices and hyperandrogenism on PCOS women without changes in telomere length or inflammatory biomarkers.
Whey Protein Isolate-Xylose Maillard-Based Conjugates with Tailored Microencapsulation Capacity of Flavonoids from Yellow Onions Skins

The objective of this study is to encapsulate flavonoids from yellow onion skins in whey protein isolates (WPI) and xylose (X), by Maillard-based conjugates, as an approach to improve the ability to entrap flavonoids and to develop powders with enhanced antioxidant activity. WPI (0.6%, w/v) was conjugated to X (0.3%, w/v) through the Maillard reaction at 90 °C for 120 min, in the presence of a flavonoid-enriched extract. Two variants of powders were obtained by freeze-drying. The glycation of WPI allowed a better encapsulation efficiency, up to 90.53 ± 0.29%, corresponding to a grafting degree of 30.38 ± 1.55%. The molecular modelling approach was used to assess the impact of X interactions with α-lactalbumin and β-lactoglobulin on the ability of these proteins to bind the main flavonoids from the yellow onion skins. The results showed that X might compete with quercetin glucosides to bind with α-lactalbumin. No interference was found in the case of β-lactoglobulin. The microstructural appearance of the powders revealed finer spherosomes in powder with WPI–X conjugates via the Maillard reaction. The powders were added to nachos, followed by a phytochemical characterization, in order to test their potential added value. An increase in antioxidant activity was observed, with no significant changes during storage.
Childlessness and health seeking behavior in resource poor setting of dang and Udayapur district of Nepal

Background: Childlessness is not problem in resource-poor area where fertility rates are high. The consequence of childlessness is very severe in low-income countries like Nepal, particularly for women. Childless women are frequently stigmatized, isolated, ostracized, disinherited and neglected by the family and local community. This may result in physical and psychological abuse, polygamy and even suicide. The aim of the study is to explore the perception of childlessness, its cause and consequences and health seeking behavior among couples in order to develop strategies for action and policy-setting.Methods: This was a qualitative study conducted in Dang and Udayapur district of Nepal. Childlessness couple were recruited through snowball sampling. Information was also gathered from key informant and Focus group discussion. All interview were audiotaped using a digital recorder.Results: Women expressed that they are being discriminated, humiliated and intimated by their family members and society for being childlessness. Despite childlessness problem with husband, women experience emotional and physical abuse. Financial constraints and unaffordable service as one of the major problems among couple that led to withdrawal or stop attending their follow up for modern treatment.Conclusions: The study concludes that childlessness women suffer from all spare of their personal and social life although childlessness is a biomedical cause. Financial hardship and family pressure made them to seek traditional healer for first treatment approach for childlessness rather than modern method of treatment. Therefore, childlessness needs to be seen as a public health issue rather than a pure medical condition. Hence, multi-sectoral (i.e., Preventive, promotive and social dimension) response to address childlessness could be valuable.
GENETIC MODEL OF LJUBIJA BRANDS DEPOSITS − RAW MATERIALS FOR PRODUCTION OF MINERAL PIGMENTS

Specific characteristics of iron ore deposits in Ljubija ore region are given by pelitoid iron ores (,,brand“) which occupy a substantial part of iron mineral resources, on which industrial production of natural iron oxide – pigments depends. This particular technology type of iron ore deposits, until recently was waste from mining production, and now when it is possible to implement new technological processes, that waste became an important commercial product. This paper presents the results of detailed geological research which lasted for a few years, as well as laboratory and tehnological tests. It presents the new data on the metallogenetic characteristics of the environment where iron oxides originate as a raw material for mineral pigments. In this paper, we answered and resolved dilemma about brand identity in adequate genetic iron types in Ljubija mining regions, about their specificity as well as the ore formations and geohistorical development. Through the technological characterization of the ore and its domain of application, we provide the basis for economic evaluation of the deposits of this very important mineral resource.
Relic neutrinos at accelerator experiments

We present a new technique for observing low energy neutrinos with the aim of detecting the cosmic neutrino background using ion storage rings. Utilising high energy targets exploits the quadratic increase in the neutrino capture cross section with beam energy, and with sufficient beam energy, enables neutrino capture through inverse-beta decay processes from a stable initial state. We also show that there exist ion systems admitting resonant neutrino capture, capable of achieving larger capture cross sections at lower beam energies than their non-resonant counterparts. We calculate the neutrino capture rate and the optimal experimental runtime for a range of different resonant processes and target ions and we demonstrate that the resonant capture experiment can be performed with beam energies as low asO(10 TeV) per target nucleon. Unfortunately, none of the ion systems discussed here can provide sufficient statistics to discover the cosmic neutrino background with current technology. We address the challenges associated with realising this experiment in the future, taking into account the uncertainty in the beam and neutrino momentum distributions, synchrotron radiation, as well as the beam stability.
EXPERIMENTAL ANALYSIS OF THE VISCOUS TUNED MASS DAMPER FOR THE ATTENUATION OF STRUCTURAL RESPONSES

This paper presents a systematic experimental investigation on the performance of a Multiple Tuned Mass Dampers (MTMDs) attached to a structural system under dynamic load excitation. A Modal Experimental Analysis (EMA) of a three-story structural frame equipped with a viscous damper system was carried out through a series of shaking table tests to evaluate the performance and verify the analysis approach. Each of the TMDs consists of a mass attached to a structural floor via Thermoplastic Polyurethane (TPU) viscous bearing. Initially, the TMD was designed solely to control single mode vibration and then the mechanism is extended for the application of controlling multimode responses. The experiment demonstrated that the proposed viscous dampers exhibit good performance in reducing the response of structures under dynamic loads, and able to control both fundamental and higher vibration modes of a Multiple Degree of Freedom (MDOF) primary system effectively. It was also evident that the attachment of the air dashpot dampers to each of TMDs lead to better efficiency on controlling the amplification of the damper mass and significantly contribute to better structural modal tuning.
The Influence of Overexpressed Fibroblast Growth Factor Receptors Towards Vitamin D Receptor Expression and Activity

(1) Background: Many malignancies are driven by mutations which affect the gene for fibroblast growth factor receptor (FGFR) 1. Previously we have documented that signal transduction from FOP2–FGFR1 fusion protein in KG1 cells downregulated the expression of vitamin D receptor (VDR) gene. In this paper we investigated if also other FGFRs were responsible for the regulation of the VDR expression. (2) Methods: We used human myeloid leukemia cells U937, and bone cancer cell line U2OS, and cell transfection methods in order to address the above questions. (3) Results: In myeloid leukemia cells overexpression of FGFR 1-4 caused shift to granulocytic differentiation, upregulated expression of VDR, and sensitized these cells to 1,25-dihydroxyvitamin D (1,25D)-induced monocytic differentiation, while in bone cells, signal transduction activated by FGF1 was not responsible for regulation of VDR expression and activity. (4) Conclusions: Since the overexpression of FGFRs occurs in many neoplasms, it may be reasonable to use 1,25D analogs in these cancers, in which overexpression of FGFRs leads to VDR upregulation.
Crust and Upper Mantle Structure Beneath the Eastern United States

The Eastern United States (EUS) has a complex geological history and hosts several seismic active regions. We investigate the subsurface structure beneath the broader EUS. To produce reliable images of the subsurface, we simultaneously invert smoothed P‐wave receiver functions, Rayleigh‐wave phase and group velocity measurements, and Bouguer gravity observations for the 3D shear‐wave speed. Using surface‐wave observations (3–250 s) and spatially smoothed receiver functions, our velocity models are robust, reliable, and rich in detail. The shear‐wave velocity models fit all three types of observations well. The resulting velocity model for the eastern U.S. shows thinner crust beneath New England, the east coast, and the Mississippi Embayment (ME). A relatively thicker crust was found beneath the stable North America craton. A relatively slower upper mantle was imaged beneath New England, the east coast, and western ME. A comparison of crust thickness derived from our model against four recent published models shows first‐order consistency. A relatively small upper mantle low‐speed region correlates with a published P‐wave analysis that has associated the anomaly with a 75 Ma kimberlite volcanic site in Kentucky. We also explored the relationship between the subsurface structure and seismicity in the eastern U.S. We found that earthquakes often locate near regions with seismic velocity variations, but not universally. Not all regions of significant subsurface wave speed changes are loci of seismicity. A weak correlation between upper mantle shear velocity and earthquake focal mechanism has been observed.