Miracle-dz/UniFAR-FTUs huggingface dataset:
The Production of Intensified Qu and Its Microbial Communities and Aroma Variation during the Fermentation of Huangjiu (Chinese Rice Wine)

In recent years, intensified Qu (IQ) has been gradually applied to brewing in order to improve the aroma of Huangjiu (Chinese rice wine). In this study, Saccharomyces cerevisiae and Wickerhamomyces anomalus solutions were added to Fengmi Qu (FMQ) from Fangxian, China to produce IQ, and brewing trial was conducted. High-throughput sequencing (HTS) was used to analyze the microbial community in fermentation broth of IQ (IQFB). Headspace solid-phase microextraction (HS-SPME) combined with gas chromatography–mass spectrometry (GC-MS) and sensory evaluation were performed to analyze volatile aroma compounds (VACs) in sample without Qu and both fermentation broths. The results showed that Pediococcus, Cronobacter, Enterococcus, Weissella, and Acinetobacter and Saccharomycopsis, Wickerhamomyces, and Saccharomyces were dominant bacterial and fungal groups, respectively. A total of 115 VACs were detected, and the content of esters including ethyl acetate, isoamyl acetate, and so on was noticeably higher in IQFB. The finding of sensory evaluation reflected that adding pure yeast to Qu could enhance fruit and floral aromas. Correlation analysis yielded 858 correlations between significant microorganisms and different VACs. In addition, prediction of microbial community functions in IQFB revealed global and overview maps and carbohydrate metabolism to be the main one. This study is advantageous for further regulation of the fermentation process of Huangjiu by microbial means.
A Novel and Validated Inflammation-Based Prognosis Score (IBPS) Predicts Outcomes in Patients with Diffuse Large B-Cell Lymphoma

Purpose We aimed to create a novel prognostic score, the inflammation-based prognosis score (IBPS). In addition, we attempted to establish and validate a nomogram to predict the overall survival (OS) of patients with DLBCL. Patients and Methods We retrospectively investigated the data of 213 patients with DLBCL diagnosed and treated in the Affiliated Hospital of Jiangnan University and used these data to develop nomograms. At the same time, 89 patients diagnosed and treated in Wuxi People’s Hospital Affiliated with Nanjing Medical University from January 2015 to June 2021 were collected as an external validation cohort. We developed IBPS through the least absolute shrinkage and selection operator (LASSO) Cox regression. The univariate and multivariate Cox regression method was used to develop the nomogram. We used the concordance index (C-index), calibration chart, time-dependent receiver operating characteristic (ROC) analysis, decision curve analysis (DCA), and the Kaplan–Meier curve were used to assess the nomogram. Results The systemic immune inflammation index (SII), prognostic nutrition index (PNI), and modified Glasgow prognostic score (mGPS) were used to construct IBPS. The Eastern Cooperative Oncology Group performance status (ECOG PS), IBPS, response to treatment, and whether accept surgery were used to construct the nomogram to predict the OS of DLBCL patients. The C-index in the training and validation cohorts were 0.844 and 0.828, respectively. According to the time-dependent ROC curve and DCA, the nomogram has good predictive accuracy and clinical net benefit. The Kaplan–Meier curve showed that according to the nomogram score, patients in the training and validation cohorts could be classified into three risk groups. Conclusion In patients with DLBCL, baseline IBPS was a reliable predictor of OS. The survival probability of DLBCL patients can be precisely predicted using the prognosis nomogram based on IBPS.
Foreign Body in the Gastrointestinal Tract in Children: A Tertiary Hospital Experience

Background: Foreign body (FB) ingestion in the gastrointestinal tract (GIT) in children is common. Although most foreign bodies will pass spontaneously, surgical intervention is required when they fail to pass. Aims and Objectives: The aim of this study was to evaluate our experience in the management of children who presented with FB in the GIT. Materials and Methods: This was a retrospective study of children that underwent laparotomy for the removal of FB in the GIT at the paediatric surgery unit of Enugu State University Teaching Hospital, Enugu over a 10-year period. Results: A total of 272 children presented with FB in the GIT during the study period, out of which 30 patients had laparotomy. This gave an operative incidence rate of 11%. There was a slight male predominance and the ages of the patients ranged from 6 months to 5 years (median 3 years). About half of the patients had no symptoms and all the patients were investigated with an abdominal radiograph. Only one-third of the patients had a predisposing factor that could have led to FB impaction. FB impaction was the most common indication for surgery, and enterotomy with FB removal was the most performed surgical procedure. The most common FB removed were tiny parts of toys, and the most common post-operative complication was surgical site infection. There was no mortality. Conclusion: FB in GIT in children could be associated with complications that require surgical treatment. FB ingestion is preventable. Focus should be placed on caregivers preventing children from ingesting FB.
Exploring Hard Samples in Multiview for Few-Shot Remote Sensing Scene Classification

Few-shot remote sensing scene classification (RSSC) is of high practical value in real situations where data are scarce and annotated costly. The few-shot learner needs to identify new categories with limited examples, and the core issue of this assignment is how to prompt the model to learn transferable knowledge from a large-scale base dataset. Although current approaches based on transfer learning or meta-learning have achieved significant performance on this task, there are still two problems to be addressed: 1) as an essential characteristic of remote sensing (RS) images, spatial rotation insensitivity surprisingly remains largely unexplored and 2) the high distribution uncertainty of hard samples reduces the discriminative power of the model decision boundary. Stimulated by these, we propose a corresponding end-to-end framework termed a hard sample learning and multiview integration network (HSL-MINet). First, the multiview integration (MI) module contains a pretext task introduced to guide the knowledge transfer and a multiview-attention mechanism used to extract correlational information across different rotation views of images. Second, aiming at increasing the discrimination of the model decision boundary, the hard sample learning (HSL) module is designed to evaluate and select hard samples via a classwise adaptive threshold strategy and then decrease the uncertainty of their feature distributions by a devised triplet loss. Extensive evaluations on NWPU-RESISC45, WHU-RS19, and UCM datasets show that the effectiveness of our HSL-MINet surpasses the former state-of-the-art approaches.
Possible Prophylactic Effect of Soy Isoflavones Genistein on Cigarette SmokeInduced Neurotoxicity in Rats’ Brains

: Neurodegenerative diseases have long been linked to Cigarette Smoke (CS). The goal of this study was to examine the neurotoxicological effects of CS on rat brains as well as any potential ameliorative benefits of genistein as a neuroprotective agent. A total of 24 adult male Wistar rats were divided into 4 different groups. Group I served as control; group II was CS Exposed (Rats are exposed to side stream CS twice daily, the duration of each exposure was 3 h with an interval of 10 min between each cigarette, using 8 to 10 cigarettes per day); group III received: both CS Exposure and Gen (Genistein dissolved in cremophor EL orally, 10 mg/kg BW orally); Group IV received Gen (Genistein alone dissolved in cremophor EL orally, 10 mg/kg b.w./day). Rats treated with CS poisoning developed biochemical and histological abnormalities. The levels of enzymic and non-enzymic antioxidants as well as neuronal enzymes like acetylcholinesterase, creatine kinase, and Lactate Dehydrogenase within the brain and serum of treated rats were significantly improved by genistein, which also significantly reduced the elevation of lipid peroxidation and normalized the CS impact. Histology data further supported the findings that CS therapy resulted in neurodegenerative changes and that soy isoflavones genistein act as antioxidants and neuroprotective agents against CS toxicity. Therefore, Genistein should be a part of a healthy diet to prevent or reduce neurological diseases caused by long-term exposure to CS.
Deep Learning Based Pilot-Free Transmission: Error Correction Coding for Low-Resolution Reception Under Time-Varying Channels

Recently, deep learning aided methods have been developed for error correction coding with quantitative constraints. However, previous studies only focus on additive white Gaussian noise (AWGN) channels, which is not sufficient for actual communication environments. In this article, we propose a novel autoencoder aided error correction coding scheme for low-resolution reception under time-varying channels. Based on the symbol extension of the proposed autoencoder and the faster-than-Nyquist (FTN) technology, pilot-free transmission can be realized without adding additional bandwidth. The transformer block is introduced to lighten and improve the decoder. Additionally, two kinds of preamplification techniques are applied for further performance boosting. Simulations show that the proposed method can achieve better performance compared with the traditional methods at high signal-to-noise ratio (SNR) under different time-varying channels without quantization. Moreover, it outperforms the previous state-of-the-art ECCNet and can achieve remarkable transmission performance even under time-varying low-resolution reception scenarios.
Protecting SOME/IP Communication via Authentication Ticket

Designed using vehicle requirements, Scalable service-Oriented MiddlewarE over IP (SOME/IP) has been adopted and used as one of the Ethernet communication standard protocols in the AUTomotive Open System Architecture (AUTOSAR). However, SOME/IP was designed without considering security, and its vulnerabilities have been demonstrated through research. In this paper, we propose a SOME/IP communication protection method using an authentication server (AS) and tickets to mitigate the infamous SOME/IP man-in-the-middle (MITM) attack. Reliable communication between the service-providing node and the node using SOME/IP communication is possible through the ticket issued from the authentication server. This method is relatively light in operation at each node, has good scalability for changes such as node addition, guarantees freshness, and provides interoperability with the existing SOME/IP protocol.
A Fuzzy-Enhanced Robust DZNN Model for Future Multiconstrained Nonlinear Optimization With Robotic Manipulator Control

Different from the common static and continuous-time dynamic problems of unconstrained/constrained nonlinear optimization, this article aims to investigate a discrete-time dynamic problem of nonlinear optimization with multiple types of constraints, which can be succinctly termed as future multiconstrained nonlinear optimization (FMCNO) problem because of the unknown future. Considering the unique advantages of neural networks with parallelism and fuzzy control systems (FCSs) with adaptivity, a fuzzy-enhanced robust discretized zeroing neural network (FER-DZNN) model is proposed to address the FMCNO problem. Specifically, by introducing a fuzzy factor outputted from an FCS with dual inputs, the FER-DZNN model is designed on the basis of an FER evolution rule and a five-step look-ahead discretization rule. Moreover, theoretical results are provided to indicate the convergence and robustness of the FER-DZNN model under various noises. Finally, two illustrative examples, including an application example to robotic manipulator control, are presented to substantiate the superior convergent and robust performance of the FER-DZNN model under various noises for addressing the FMCNO problem.
Graphs with the unique path property: Structure, cycles, factors, and constructions

In a directed graph with the unique path property, there is a unique directed path of a given length n $n$ between any ordered pair of its t $t$ vertices. Such graphs, their paths, cycles, factors, and other properties, were extensively studied during the years, mainly in the context of de Bruijn graphs, forming the most important family of such graphs. Such a graph is equivalent to a t × t $t\times t$ binary matrix A $A$ for which A n = J ${A}^{n}=J$ , where J $J$ is the all‐ones t × t $t\times t$ matrix. In this paper, some new results on the structural properties of such graphs, which are not necessarily de Bruijn graphs, are proved. We mainly concentrate on such graphs for which each vertex has in‐degree two and out‐degree two. The minimum number and the maximum number of vertices which are reached from a given vertex using all paths of length smaller than n $n$ are considered. We provide an exact formula for the number of factors in these graphs and show that this number depends only on the number of alternating cycles in the graph, where in an alternating cycle every two consecutive edges have opposite directions in the cycle. Constructions of such graphs using several methods are presented. In particular, we present a new construction which provides a large set of such graphs with long alternating cycles. We define the integral graph and the derivative graph and implement these definitions on this family of graphs. Various properties from the point of view of the de Bruijn graph and the theory of nonsingular shift‐registers sequences are also considered. Finally, generalizations for graphs in which the in‐degree and the out‐degree of each vertex are greater than two are also discussed.
Cilia and Cancer: From Molecular Genetics to Therapeutic Strategies

Cilia are microtubule-based organelles that project from the cell surface with motility or sensory functions. Primary cilia work as antennae to sense and transduce extracellular signals. Cilia critically control proliferation by mediating cell-extrinsic signals and by regulating cell cycle entry. Recent studies have shown that primary cilia and their associated proteins also function in autophagy and genome stability, which are important players in oncogenesis. Abnormal functions of primary cilia may contribute to oncogenesis. Indeed, defective cilia can either promote or suppress cancers, depending on the cancer-initiating mutation, and the presence or absence of primary cilia is associated with specific cancer types. Together, these findings suggest that primary cilia play important, but distinct roles in different cancer types, opening up a completely new avenue of research to understand the biology and treatment of cancers. In this review, we discuss the roles of primary cilia in promoting or inhibiting oncogenesis based on the known or predicted functions of cilia and cilia-associated proteins in several key processes and related clinical implications.
Location- and lesion-dependent estimation of mammographic background tissue complexity

Abstract. We specify a notion of perceived background tissue complexity (BTC) that varies with lesion shape, lesion size, and lesion location in the image. We propose four unsupervised BTC estimators based on: perceived pre and postlesion similarity of images, lesion border analysis (LBA; conspicuous lesion should be brighter than its surround), tissue anomaly detection, and local energy. The latter two are existing methods adapted for location- and lesion-dependent BTC estimation. For evaluation, we ask human observers to measure BTC (threshold visibility amplitude of a given lesion inserted) at specified locations in a mammogram. As expected, both human measured and computationally estimated BTC vary with lesion shape, size, and location. BTCs measured by different human observers are correlated (ρ=0.67). BTC estimators are correlated to each other (0.84<ρ<0.95) and less so to human observers (ρ≤0.81). With change in lesion shape or size, LBA estimated BTC changes in the same direction as human measured BTC. Proposed estimators can be generalized to other modalities (e.g., breast tomosynthesis) and used as-is or customized to a specific human observer, to construct BTC-aware model observers with applications, such as optimization of contrast-enhanced medical imaging systems and creation of a diversified image dataset with characteristics of a desired population.
The Importance of Transformational Leadership and Job Resources to Increase Lecturer Engagement: Learned from Indonesia Case

Purpose: The aim of this study is to examine whether transformational leadership will significantly affect lecturer engagement and whether job resources will mediate the effect of transformational leadership on lecturer engagement. Theoretical framework: Recent literature has reported that job resources and transformational leadership strongly influence employee engagement. Job resources mediate the effect of transformational leadership on employee engagement. Design/methodology/approach: This study applied non-probability sampling and collected 102 samples from lecturers from urban private universities, especially in Jakarta and other big cities. SEM-PLS is used as a tool to calculate data statistically. Findings: The study's results prove that transformational leadership has a positive and significant effect on engagement, as does job resources. Furthermore, job resources are proven to mediate the effect of transformational leadership on engagement. Research, Practical & Social implications: The results of this research imply that organizations, especially private universities can present and influence transformational leaders to lead organizations and improve job resources that lecturers or employees can access Originality/value: The value of the study is the first study on transformational leadership in Indonesia urban private universities.
Evaluation of the Fracture Resistance of Conservative and Ultraconservative Access Cavity Designs with Different Treatment Modalities: An In Vitro Study

Introduction The aim of this study was to evaluate the fracture resistance of endodontically treated mandibular molars using traditional and conservative access cavity preparation. Materials and Methods In this in vitro study, 100 extracted healthy human mandibular molars were selected and divided into 10 groups (n = 10). Healthy teeth in one group were considered the control group. In three groups, traditional access cavity preparation was done (groups A) without two marginal ridges (A1), with one marginal ridge (A2), and with two marginal ridges (A3). In three groups (group B), two separate access cavities with a dentinoenamel roof without two marginal ridges (B1), with one marginal ridge (B2), and with two marginal ridges (B3) were prepared. In three other groups (groups C), two separate access cavities were prepared only with a dentinal roof without two marginal ridges (C1), with one marginal ridge (C2), and with two marginal ridges (C3), on which root canal treatment was performed afterward. Then, these teeth were subjected to force until fracture. The fracture force and fracture mode of each tooth were recorded and compared between groups by ANOVA, Tukey's post hoc, and chi-square tests using SPSS ver. 23 (IBM, Somers, NJ, USA). Results The control teeth had the highest mean fracture force (2804.5 ± 338.5 N), followed by a conservative access cavity with a dentinoenamel roof and two marginal ridges (2360.4 ± 181.72 N) and a conservative access cavity with a dentinoenamel roof and one marginal ridge (1812.8 ± 263.9 N), respectively. The lowest mean fracture force was found for the conventional access cavity group without two marginal ridges (399.4 ± 95.2 N). Conclusion In the condition of this study, with two separate access cavities in mandibular molars and maintenance of the marginal ridges, it is possible to provide teeth with higher fracture resistance against occlusal forces.
A Prospective Comparison of Octyl-2-Cyanoacrylate and Suture in Facial Wounds

The study aimed to evaluate the efficacy of octyl-2-cyanoacrylate as well as sutures as a wound closure material. Whether octyl-2-cyanoacrylate can be used as an alternative to suture in the closure of facial wounds. Out of total of 19 wounds, 11 wounds were closed with sutures and tissue adhesive both, out of rest 8 wounds, 4 wounds were closed using sutures alone and in 4 wounds, closure was done with tissue adhesive alone. Therefore, a total of 15 facial wounds were divided into two groups: Group-I Cases in whom 3-0 Black silk suture was used for closure of the wound and Group-II Cases in whom Dermabond (Octyl-2-Cyanoacrylate) was used for closure of the wound. Results showed that Octyl-2-cyanoacrylate offered the benefit of decreased procedure time with less pain, no need for its removal, and better cosmetic outcome compared to sutures.
Conditionals as interpersonal devices in Late Modern English women’s scientific writing

It is widely recognised that attaining best possible reception of one’s writing within the scientific community is among the main factors that contribute to the rhetorical profile of scientific prose. Authors not only have to negotiate meaning but also to persuade their peers (Allen, Qin & Lancaster, 1994; Atkinson 1996, 1999; Bazerman, 1988; Hyland, 1998, 2000). This is perhaps most remarkable when the position within the scientific community is disadvantageous, as in the case of female scientists during the Late Modern English period. (Crespo, 2012; Schiebinger, 1989, 2003). Conditionals present an array of functions of an interpersonal nature, these used to negotiate meaning or to achieve a better reader response. Whether they are used to state shared assumptions, to narrow the scope or mitigate the force of a claim, to show humility by rhetorically doubting one’s own wording or underlining one’s uncertainty, or to directly express politeness, conditionals can be characterised as “rhetorical device[s] for gaining acceptance for one’s claims” (Warchal, 2010, p. 141). The aim of this article is to analyse the use of conditionals as interpersonal, negotiating devices in the work of female scientists in the eighteenth and nineteenth centuries. To this end, texts written by women included in the Coruña Corpus of English Scientific Writing (Moskowich, 2011) will be searched for conditional markers, and the results will be analysed from a functional point of view, highlighting the particular ways in which female scientists used these devices across disciplines and through the period.
A CONCEPTUAL FRAMEWORK OF CONSUMERS’ INTENTION TO PURCHASE HALAL FOOD AMONG GEN Z IN MALAYSIA

The purpose of this paper is to develop a conceptual framework that provides insights and aids in understanding the factors that influence consumers’ intention to purchase halal food among Gen Z in Malaysia. This concept paper explains the relationship between attitude, subjective norms, and perceived behavioural control towards purchase intention on halal food among Gen Z in Malaysia. Based on an extensive literature review, this paper proposes a conceptual framework for understanding the relationship and relevant insights on its development. The study uses a descriptive research approach in order to gain fruitful insights as well as to explain the relationship between attitude, subjective norms, and perceived behavioural control that influence purchase intention on halal food among Gen Z in Malaysia. A structured questionnaire will be given to the respondents in assessing their purchase intention on halal food. The results of this study discovered the importance of consumers’ purchase intention of halal food products. It is hoped that this paper would serve as a reference to Malaysian Statutory bodies and halal food industry specifically on the current purchase intention of halal food among Malaysia’s Gen Z. Keywords: Attitude; Gen Z; Purchase Intention; Perceived Behavioural Control; Subjective Norms