Miracle-dz/UniFAR-FTUs huggingface dataset:
Neurodevelopmental Outcome in Children with Down Syndrome

Background: Down syndrome is the most common identifiable genetic cause of intellectual disability and birth defects. Although intellectual disability and hypotonia are present in virtually all individuals with DS, the expression of other DS-associated congenital and acquired medical complications is variable. Aim of the work: The aim of the study is to determine the neurodevelopmental, behavioral, mentality outcome and associated neurological complications in children with Down Syndrome. Methods: Forty children with Down syndrome were enrolled from June 2016 to March 2017 in the genetic clinic in Fayoum University Hospital. For all, EEG study was done; evaluation using Portage program, and serum TSH, free T3and free T4 was measured. For selected cases fundus examination, ABR, and MRI was done. Results: There was significant developmental delay in motor abilities, selfhelp, social, cognitive, communication, and language skills in our cases. There was a significant relation between motor development, self-help skills, communication skills, language development and head circumference; however, no significant relation was found between cognitive skills and head circumference. There was a significant relation between delay in cognitive skills and EEG abnormalities. There was no significant relation between cytogenetic type of Down Syndrome, presence or absence of cardiac abnormalities, and portage score. Conclusion: All items of developmental outcome were affected in Down Syndrome. The Portage scores (in motor development, self-help skills, communication skills, language development) were affected by microcephaly and EEG abnormalities were found in cases with cognitive disabilities.
Fournier’s gangrene: a clinical profile of 30 cases

Fournier’s gangrene is a rapidly progressive necrotizing fasciitis of the perineal, genital or perianal regions with obliterative endarteritis and necrosis of the adjacent skin. It has a history of male preponderance but is also known to occur in women and in children. Though it is very rarely found in children most of the cases are reported in infants. According to a study conducted by Eke the lower incidence in women is attributed to under repoting. Baurienne in 1764 and Avicenna in 1877 had described the same disease earlier. It was noticed that those cases were neither idiopathic nor fulminant. In 1883, Jean Alfred Fournier (1832-1914) gave the first clinical description of idiopathic rapidly progressive gangrene of the male external genitalia.
EFFECTS OF NATURALISTIC TIME DELAY ON PROMOTING FUNCTIONAL REQUESTS USING AAC IN PRESCHOOLERS WITH AUTISM SPECTRUM DISORDERS

OF THESIS EFFECTS OF NATURALISTIC TIME DELAY ON PROMOTING FUNCTIONAL REQUESTS USING AAC IN PRESCHOOLERS WITH AUTISM SPECTRUM DISORDERS The purpose of this study was to teach preschool children with autism spectrum disorders to make requests with a speech generating device using a naturalistic time delay prompting procedure. The participants in this study were two males, enrolled in a public preschool program, between four and five years old. Both participants showed significant delays in expressive communication requiring alternative and augmented communication. The study utilized a multiple probe design across behaviors. Results showed utilizing naturalistic time delay increases independent requests using a speech generating device.
Variation in Dry Matter Production, Partitioning, Yield and its Correlation in Groundnut (Arachis Hypogaea L.) Genotypes

Groundnut (Arachis hypogaea L.) is one of the world’s most popular oilseed crops. Nut yield in groundnut is polygenically controlled and is influenced by its component characters. A field experiment was conducted to study the variation in respect of kernel yield and its component characters along with dry matter production and partitioning at important vegetative and reproductive growth stages in nineteen genotypes of groundnut. The correlation studies were also conducted to prioritize morphological and physiological traits for improving yield. Genotypes exhibited significant differences among them in respect of kernel yield and its all attributes. Highly significant differences were recorded in respect of dry matter production and partitioning to different plant parts at pre-anthesis (30 DAS) and post-anthesis pod filling (60 DAS) stages.
Occurrence and location of Transmissible Venereal Tumors in Dogs seen at the Universidade Federal Rural do Rio de Janeiro Veterinary Hospital: Oncology Sector between 2010 and 2014.

ABSTRACT. Araujo D.C.C. , Antonioli T. , Costa T.S. , de Carvalho J.R. G. , Laguna A.G. V. , Ramadinha R.H. R. & Fernandes J.I. Occurrence and location of Transmissible Venereal Tumors in Dogs seen at the Universidade Federal Rural do Rio de Janeiro Veterinary Hospital: Oncology Sector between 2010 and 2014. [Ocorrencia e localizacao do Tumor Venereo Transmissivel em caes atendidos entre 2010 e 2014 no Setor de Oncologia do Hospital Veterinario da Universidade Federal Rural do Rio de Janeiro, Brasil. ] Revista Brasileira de Medicina Veterinaria, 38(3):277-280, 2016. Programa de Residencia em Medicina Veterinaria, Instituto de Veterinaria, Universidade Federal Rural do Rio de Janeiro, BR-465, Km 7, Seropedica, RJ 23851-970, Brasil. E-mail: dayanecaico@hotmail.com The Transmissible Venereal Tumor (TVT) is a round cell neoplasm mostly affecting the genital of dogs. They can affect both sexes, and most animals are sexually active. Metastases, which occur in less than 5% of cases, occur through lymphatic or hematogenous. Diagnosis can be made by cytology and the most effective treatment is chemotherapy with vincristine sulfate. This study reports the occurrence of TVT from January 2010 to December 2014 in the UFRRJ Veterinary Hospital at the Oncology sector; clinical records were reviewed: 1,522 animals were seen and 123 (8.08%) presented TVT. Of 123 animals afflicted, 71.54% were adults, 23.57% were senior and 4.87% had less than a year. A higher frequency of females (74) was observed, when compared to males (49). A higher incidence in mutts (78.05%) was found, followed by poodles (7.32%), pinscher and Labrador (3.25%). Genital location was most common (79.04%), followed by a genito-cutaneous presentation (8.94%), nasal (5.69%), cutaneous (5.69%) and ocular (0.81%). It can be linked with large quantities of stray dogs and poor animal control policies in the region.
Influence of Basal and Top Dressing Nitrogen Fertilization on Symbiotic Traits and Microbial Population in Soybean

Soybean [Glycine max (L.) Merrill] is an important pulse-cum-oilseed crop which belongs to family Papilionaceae. It is grown in tropical, sub-tropical and temperate regions of the world and is believed to be originated in East Asia. The area under soybean has been increasing rapidly since 1970’s as compared to other crops. At present the crop is grown on 6% of the world’s arable land (Hartman et al., 2011). I n India during 2015-16, soybean was grown on an area of 11.6 million hectare, with a production of 8.5 million tonnes and International Journal of Current Microbiology and Applied Sciences ISSN: 2319-7706 Volume 8 Number 11 (2019) Journal homepage: http://www.ijcmas. com
Study on Image seeking behaviour of Iranian Architects at Shahid Beheshti University

Access to the required information in all available scientific disciplines is one of the most important factors in the survival of that field. In the architecture field, the type of information format differs from other disciplines. In this field, images are important for performing architectural activities as well as training. The purpose of this study was to identify the behavior of image in the architecture of Shahid Beheshti University. Therefore, by reviewing related retrieval texts, information behavior, image retrieval, and architecture, the discovery of the importance of the image in this field and the features of image retrieval and image retrieval solutions were addressed. The present study is an applied target and descriptive survey method. The statistical population of the study consists of two groups of students and professors in architecture of Shahid Beheshti University. The number of professors and students in the field of architecture was 1262, and it was not possible to examine all of the group members, so they were sampled from the community. To determine the sample size, the Cochran formula was used and the sample size in this formula was 296, but slightly more than the sample size, 300 questionnaires were distributed. After collecting the questionnaires and analyzing the responses, SPSS software was used to identify the characteristics of the behavior of the specialists in the field of architecture. The results showed that the architects mainly used images for identifying creative and the use of details of architectural structures. In order to identify the need for images, they are required mainly used social networks, specialized search engines, specialized image databases and consult with their professionals. The type of image content they used was mostly photos, maps and charts. Find them in engines and image databases by limiting the size of the image and following related links as long as the image was taken. One of the major obstacles in finding images for architects was the lack of familiarity with the way they were searched. Creativity, proximity to the subject, the credibility and quality of the images were the criteria for selecting content. Easy to use and easy to navigate was the main criterion for selecting the content delivery site. The amount of library utilization and its services by architectural experts were as acceptable as the use of search engines and the Internet, which requires the planning and development of services for the benefit of library architects.
Effect of fatty acids on the accelerated sulfur vulcanization of rubber by active zinc/carboxylate complexes

The effect of fatty acids with different aliphatic chain lengths on the accelerated vulcanization reaction of isoprene rubber was investigated through the generation of new intermediates composed of dinuclear bridging bidentate zinc/carboxylate complexes. Using the combination of in situ time-resolved Fourier-transform infrared spectroscopy and in situ time-resolved zinc K-edge X-ray absorption fine structure spectroscopy, the essential complex structure of the intermediates formed during the vulcanization reaction of isoprene rubber was determined to be independent of the aliphatic chain length of fatty acids. However, the reactivity of arachidic acid with ZnO was found to be low, which prolonged the induction period and curing time, and slowed down the curing rate in the vulcanization of isoprene rubber. These results help to understand the complicated vulcanization reaction of rubber, especially natural rubber, which inherently contains various fatty acids. The results obtained in this study are important for developing well-designed high-performance natural rubber products in the future.
The impact factors on the competence of big data processing

A major challenge of using volunteer computing (VC) for big data problems is the opportunistic environment. In such a dynamic, unreliable, and heterogeneous environment, there exist many uncertain factors that may impair the competence of big data processing. This paper explores these factors and their impact, aiming at exposing the original impaired performance that the undedicated environment of VC can achieve under the impact. Our investigation on this issue is four-fold. First, we define a number of impact factors to represent the opportunistic features of VC environment. Second, we model a distributed hash table-based MapReduce approach to process big data. Third, we proposes an ideal computing environment and then inject impact factors into the running MapReduce to quantitatively evaluate how the performance is impaired. Finally, we analyze the evaluation results to figure out the cause of impact and predict optimization potentials. The developers, who plan to construct MapReduce frameworks by using commodity computers or voluntary cycles on the public internet, will benefit from the evaluation results when considering performance requirements.
Characterizing the Evolution of Contact Area in Frictional Interfaces

Seemingly static interfaces between two solids are in fact dynamic. These multicontact interfaces (MCIs) exert enormous stresses on tiny contact areas, causing time-dependent deformation. Though these phenomena are ubiquitous (e.g from micromachines to plate tectonics), their underlying mechanisms are not yet well understood. By constructing a novel apparatus, we may now take real-time, 2D measurements of the real contact area in an interface over a variety of normal loads and time steps. Given that the real contact area of an interface may be used as a proxy for frictional strength, this area based tribometer allows for an investigation into the underlying dynamics of frictional interfaces. Furthermore, by varying geometric and elastic properties of samples, we induce variations in the 2D structure of contact growth, which give insight into the mechanisms that produce deformations in frictional interfaces.
Fanaticism: Reflections based on phenomena in the analytic field*

ABSTRACT The paper presents and discusses hypotheses related to the manifestation of fanatical aspects in the analytical field. Initially, fanaticism is discussed as a social phenomenon. In sequence, clinical facts are presented. The first hypothesis involves factors related to primitive symbioses that manifest themselves mainly in adolescence, through adherence to religions, ideologies and other social facts. Clinical vignettes of adult patients deepen the study of possible factors that contribute to fanatical behaviour. It is proposed that container/contained relationships experienced in childhood as insufficient and fraudulent, and defensive narcissistic organizations, articulated with early inculcations of fanatic configurations, originate fantasies which manifest themselves as fanaticism. Deficits in the symbolisation processes, resentment and transformation into hallucinosis, among others, are presented as clinical facts. The text ends with analogies between the delusions of the Schreber case and fanatical behaviour.
Gaining Insights Into Multiple Sclerosis Lesion Characteristics from Brain Tissue Microstructure Information: A Multi-Compartment T2 Relaxometry Approach

Clinical trends and pathogenetic ways of onset and progression of Multiple Sclerosis (MS) in patients suggest that MS is a highly heterogeneous disease. MS is predominantly a White Matter (WM) disease, which is mainly composed of myelinated axons and neuroglia type cells. Demyelination and axonal loss characterize the condition of MS in a patient. However, they follow varying trends in patients. In this work, we propose a method in which T2 relaxometry data is used to obtain a quantitative brain tissue microstructure information. This information is then studied to check its corroborations with pathogenetic understanding of MS in literature.
Adequacy of clinical information supplied by clinicians for histopathologic diagnosis: The university of Benin teaching hospital experince

Background: The volume of workload in histopathology laboratories need to be accurately measured so that resources can be used appropriately in a challenging clinical environment. Aims: The main objective of this work is to assess the adequacy of clinical information provided by clinicians requesting for histopathological investigations. Materials and Methods: A total of 1659 sequential histopathological request forms sent to Department of Histopathology of the University of Benin Teaching Hospital between January 1, and December 31, 2005, were retrospectively studied and analyzed. The provision of data by surgeons and physicians were compared in a Microsoft Excel 2000 Spreadsheet using the Chi-square test with Yates's correction where appropriate. Given the number of variables being assessed, a Bonferonni correction was applied, and a value of P = 0.001 was therefore considered the limit of significance. Results: A total of 1659 pathology request cards were audited in this study. Of these, 1382 cases accounting for 83.3% were a request made by surgeons while 277 constituting 16.7% were a request sent by physicians. Hence, the ratio of a request made by surgeons and physicians were 5:1. Among the request made by surgeons, the most common request was from the Surgery Department accounting for 783 (47.2%) of all requests. Among the 277 requests made by physicians, the department of internal medicine had the highest volume accounting for 122 (7.35%) of all cases. A total of 1415 out of 1659 were found to be inadequately completed accounting for 85.3%. There were significant differences in the information on ethnicity, date, time and clinical summary recorded by surgeons and physicians and the P < 0.001, respectively. Conclusion: Majority of the pathology request cards sent by clinicians are inadequately completed with an extremely high preanalytic phase errors.
Physical therapy to improve mobility following surgery for multiple ligament knee injuries: A case report

Background and purpose: The purpose of this case report is to provide a student physical therapist’s prospective in managing a patient with multiple knee ligament injuries and the clinical decision making process used to choose the most effective physical therapy interventions to restore knee mobility following surgical reconstruction. Case description: The patient is a 21-year-old male nine weeks status post elective anterior cruciate ligament autograft Bone-Tendon-Bone reconstruction, medial/ lateral meniscal repair and debridement of synovitis multiple compartments and sprain to the posterior cruciate ligament. His chief complaints post-operatively were pain in right knee, limited range of motion and generalized weakness of right knee since the surgery. Intervention: Physical therapy management included modalities and soft tissue mobilization for inflammation and pain control, joint mobilizations, patella mobilizations, contract and relax techniques, manual stretching and low load long duration stretches in order to improve mobility. Isometric and isotonic exercises focused on increasing quadriceps activation and hip strength. Balance and gait training was provided to improve functional mobility. Outcomes: Patient showed improvements with pain level, range of motion, strength, flexibility, gait, and Lower Extremity Functional Scale. At discharge, patient reported no pain. Right knee flexion was equal to 124° improved from 89° and right knee extension improved to -3° from 10°. Patient had varying results and fluctuations in his range of motion throughout treatment, but overall showed mobility gains. LEFS at initial visit was 25/80 and improved to 43/80 upon discharge. Discussion: Patient presented with complex knee injury following ACL reconstruction and meniscal repair and as a physical therapy student, this patient case required significant clinical reasoning and monitoring. Overall patient responded positively to a combination of knee mobility interventions. The interventions that resulted in the most in-session gains included Proprioceptive neuromuscular facilitation contract-relax technique to hip flexor group and low load long duration stretch to the hamstrings. There is little literature on treating a patient with a multiple ligament knee injury. This case report demonstrates the importance of completing test/retest following each intervention to asses for tissue and joint irritability in order to progress patient appropriately. Further research needs to be completed to investigate effectiveness of treatments for multiple ligament knee injuries. Correspondence to: Heather Disney, PT, DPT, MTC, OCS, University of Saint Augustine for Health Sciences, San Marcos Campus, USA, Tel: 6192064969; E-mail: hdisney@usa.edu
Lost but revived. Revisiting the medieval village of Nieuw‐Roeselare (Flanders) using large‐scale frequency‐domain multi‐receiver EMI and landscape archaeological prospection

During the 10th to 13th centuries, the rural settlement landscapes of the County of Flanders underwent major changes. Complex interactions between urbanization, growing comital power, demographic changes and rural development formed the basis for intensified reclamations of the landscape. Based on historical research, the ab nihilo plantation of grouped rural settlements by the counts and other landlords played an important role in the organization and systematization of these reclamations. To date, however, archaeological attention for these grouped settlements is scarce, mainly due to Flanders' build‐up and urbanized character. This article describes the renewed cross‐disciplinary landscape archaeological research at the site of the lost village of Nieuw‐Roeselare (northern East Flanders), which was the first medieval village to be partly excavated in Flanders between 1967 and 1979. Believed to have been planted in 1241 and lost to floods in 1375, little is known historically about the site nor does the modern‐day polder landscape show any remnants of a former settlement. Now, a large‐scale cross‐disciplinary prospection comprising 35 ha of frequency‐domain multi‐receiver electromagnetic induction (EMI), oblique aerial photography, augering, pseudo‐two‐dimensional tomography and site specific artefact‐accurate field walking, allowed to define the settlement's full extent, clarify its geographical context and identify its morphology as a planted settlement in the context of the medieval landscape reclamations.
Water Markets, Water Courts, and Transaction Costs in Colorado

Water markets increasingly facilitate adaptation to water scarcity, but transaction costs can be barriers to expanded water marketing, particularly under water rights law in the western United States. However, transaction costs are rarely measured, and existing research commonly overlooks how transaction costs differ across individual water transfers and uncertainty in those costs. We collected hundreds of estimates of procedural transaction costs—costs incurred by transfer proponents for legal and hydrologic experts—by surveying 100 water professionals in the state of Colorado. There, water markets are among the most active in the United States, convey perhaps the most clearly defined private property rights of any state, and, unique to Colorado, require approval from specialized water courts. We elicited costs for water transfers with differing physical and legal characteristics, and we elicited separate assessments of (i) probabilities of legal outcomes for water transfers and (ii) transaction costs conditional on those outcomes. Then, we estimated expected transaction costs with a statistical model that combines (i) with (ii). The model reveals systematic differences in transaction costs, with scale economies and higher transaction costs for water‐scarce regions, senior water rights, and higher‐conflict legal outcomes. It also shows substantial transaction cost uncertainty, which itself can discourage trading. Our novel survey and estimation procedure develops a replicable approach for measuring transaction cost heterogeneity and uncertainty. Additionally, qualitative survey data we collected indicate transaction costs have increased over time due to growing competition for scarce water and that, despite high transaction costs, specialized water courts offer unique benefits.