Miracle-dz/UniFAR-FTUs huggingface dataset:
Sexuality education: Different attitudes among incoming and outgoing Nursing undergraduates

Objective: To evaluate whether attitudes towards sexuality acquired by students during a Spanish nursing degree are sufficient for their performance in professional practice. Methods: This is a descriptive, cross-sectional, and quantitative study based on a self-completion survey composed of standardized scales that compare sexual attitudes among 101 first-year students with 86 fourth-year students. The 187 nursing students, 24 men and 163 women were between 18 and 60 years old (Mage=21.21, SD=5.48). The evaluative instrument was an anonymous questionnaire that consisted of sociodemographic questions and two standardized scales: Attitudes Towards Sexuality Scale (ATSS-28) and Double Standard Scale (DSS). Results: Comparison between cohorts using the Mann-Whitney U test proved to be close to being significant in the ATSS, U=3625.50, z=-1.95, p=. 052 and significant in DSS, U=3560.50, z=-2.13, p=. 034. These findings indicate that fourth-year students have more positive attitudes towards sexuality and less rigid adherence to gender roles. In addition, a medium negative correlation, rs=-. 307, p=. 001, between ATSS and DSS was obtained, showing a positive association between attitudes and less adherence to gender roles. These results suggest that nursing degree training had a positive impact on sexual attitudes. Conclusion: Healthcare professionals are centrally involved in the care of patients and families. Nurses’ attitudes towards sexuality are important in terms of patient comfort and the accessibility and acceptability of care. Implementation of training in sexuality has a positive effect on nursing care and favours the establishment of global health strategies. Descriptors: Attitude of Health Personnel; Education; Gender identity; Nurses; Sexuality.
A Prospective observational clinical study to assess the maternal- fetal outcome in teenage pregnancy

Background: Teenage pregnancy due to changing social conditions, it’s important to study the implications of the maternal and fetal health. It is a serious health problem, more so in developing countries like India. Aim: To assess the fetomaternal outcome in teenage pregnancy. Material and methods: This was a prospective observational study conducted in the department of gynaecology and obstetrics in Patna medical college and Hospital, Patna, Bihar, India, for 12 months from July 2019 to July 2020. It included 50 cases of primigravida teenage pregnancies and 50 cases of adult pregnancies. Primigravida teenage mothers aged 13-19 years were taken as case and primigravida adult mothers aged20-30 years were taken as control. Results: The results show maximum number of teenage mothers belonged to the age group of 16-19 years (98%). In teenage mothers more cases (56%) were related to lower socio economic status than adult mothers (28%). The study shows that majority of cases (74%) of teenage mothers were illiterate as compared to adult mothers in which 26%were illiterate and shows that ante partum & postpartum complications were much higher in teenage mothers as compared to adult mothers. In our study antenatal complications were higher among teenage mothers as compared to adult mothers. Conclusion: Prevention of teenage pregnancy and reduced complications of teenage pregnancy can be achieved by improving the utilization of family planning services to reduce the rate of teenage pregnancies and minimizing their hazards and to prevent further pregnancies (by post-partum IUCD).
Timing of intraoperative crystalloid infusion may decrease total volume of infusate without affecting early graft function in live related renal transplant surgery: A randomized, surgeon-blinded clinical study

Introduction: Early graft function is crucial for successful kidney transplantation. Intravascular volume maintenance is paramount in ensuring reperfusion of transplanted kidney. This study was planned to compare whether the timing of fluid infusion can help to decrease amount of fluid given without altering early graft function during renal transplantation. Materials and Methods: The present study included forty recipients, randomized into standard (Group-S) or targeted fluid therapy (Group-T). Group S received fluid according to conventional fasting deficit while Group T received at 1 ml/kg/h from the start of surgery till start of vascular anastomosis after which fluid infusion rate in both group was increased to maintain a central venous pressure of 13–15 mm of Hg till reperfusion. Primary outcome measured was serum creatinine level on first postoperative day while secondary outcomes were IV fluid given, perioperative hemodynamics, onset of diuresis, graft turgidity, urine output, and renal function during first 6 postoperative days. Results: The study showed Group T postoperatively had early fall in serum creatinine (day 3) than S (day 6) although this difference was not statistically significant. Group T had received significantly less fluid per kg of dry weight (T-42.7 ± 9.7 ml/kg, S-61.1 ± 11.1 ml/kg, P < 0.001), had early diuresis, better graft turgidity and urine output than Group S. Conclusion: Targeted hydration significantly decreases the total amount of fluid infused during the intraoperative period without altering early graft function. Targeted hydration during vascular anastomosis produced stable hemodynamics and early diuresis without any side-effects pertaining to hypo or hyper-volemia. Clinical trial identifier number-CTRI/2016/07/007111.
Depressive symptoms in non-alcoholic fatty liver disease are identified by perturbed lipid and lipoprotein metabolism

Non-alcoholic fatty liver disease (NAFLD) and depression are common disorders and have bidirectional contributing relationships to metabolic syndrome. We aimed to determine whether a fasting serum signature of recent, self-reported depressive symptoms could be identified in a heterogeneous NAFLD cohort using nuclear magnetic resonance (NMR)-based metabolomics integrated with clinical chemistry. Serum nuclear magnetic resonance (NMR) metabolite profiles and corresponding clinical chemistry were compared between patients with depressive symptoms in the last 12-months (n = 81) and patients without recent depressive symptoms (n = 137 controls) using multivariate statistics. Orthogonal partial least squares discriminant analysis (OPLS-DA) of the biochemical and metabolomic data identified NAFLD patients with recent depression with a cross-validated accuracy of 61.5%, independent of age, sex, medication, and other comorbidities. This led to the development of a diagnostic algorithm with AUC 0.83 for future testing in larger clinical cohorts. Serum triglycerides, VLDL cholesterol, and the inflammatory biomarker GlycA were key metabolites increased in patients with recent depressive symptoms, while serum glutamine level was reduced. Here, serum NMR metabolite analysis provides a link between disturbed lipid metabolism, inflammation, and active mental health issues in NAFLD, irrespective of disease severity.
Into the Eyes of the Referee: A Comparison of Elite and Sub-Elite Football Referees’ On-Field Visual Search Behaviour when making Foul Judgements

In foul decision-making by football referees, visual search is important for gathering task-specific information to determine whether a foul has occurred. Yet, little is known about the visual search behaviours underpinning excellent on-field decisions. The aim of this study was to examine the on-field visual search behaviour of elite and sub-elite football referees when calling a foul during a match. In doing so, we have also compared the accuracy and gaze behaviour for correct and incorrect calls. Elite and sub-elite referees (elite: N = 5, Mage ± SD = 29.8 ± 4.7yrs, Mexperience ± SD = 14.8 ± 3.7yrs; sub-elite: N = 9, Mage ± SD = 23.1 ± 1.6yrs, Mexperience ± SD = 8.4 ± 1.8yrs) officiated an actual football game while wearing a mobile eye-tracker, with on-field visual search behaviour compared between skill levels when calling a foul (Nelite = 66; Nsub−elite = 92). Results revealed that elite referees relied on a higher search rate (more fixations of shorter duration) compared to sub-elites, but with no differences in where they allocated their gaze, indicating that elites searched faster but did not necessarily direct gaze towards different locations. Correct decisions were associated with higher gaze entropy (i.e. less structure). In relying on more structured gaze patterns when making incorrect decisions, referees may fail to pick-up information specific to the foul situation. Referee development programmes might benefit by challenging the speed of information pickup but by avoiding pre-determined gaze patterns to improve the interpretation of fouls and increase the decision-making performance of referees.
CD20-Targeted Therapy Ablates De Novo Antibody Response to Vaccination but Spares Pre-Established Immunity.

To obtain a deeper understanding of poor responses to COVID-19 vaccination in lymphoma patients, we assessed blocking antibodies, total anti-spike IgG, and spike-specific memory B cells in the peripheral blood of 126 patients with lymphoma and 20 age-matched healthy controls 1 and 4 months after COVID-19 vaccination. Fifty-five percent of patients developed blocking antibodies post-vaccination, compared to 100% of controls. Evaluating patients last treated from days to nearly 18 years prior to vaccination, time since last anti-CD20 was a significant independent predictor of vaccine response. None of 31 patients who had received anti-CD20 treatment within 6 months prior to vaccination developed blocking antibodies. In contrast, patients who initiated anti-CD20 treatment shortly after achieving a vaccine-induced antibody response tended to retain that response during treatment, suggesting a policy of immunizing prior to treatment whenever possible.
‘When a pandemic wears the face of a woman’

The advent of coronavirus on the world scene in general and Zimbabwe in particular has challenged communities. By and large, the pandemic has disrupted lives. Its rapid transmission and deadliness called for extra-ordinary responses as a way of containment. Zimbabwe, like the rest of the world imposed a strict lockdown which commenced on 30 March 2020 and has been reviewed fortnightly to different levels. While the intentions of the lockdown were noble, evidence on the ground reveals that it created other problems which brought to the fore the gender power dynamics that defines most African societies. This study, therefore, seeks to find out the effects of the responses to COVID-19 on women. The focus will be on how religion has to a large extent influenced the various experiences that women have gone through during this period. The paper utilizes African Womanist theory as a way of starting constructive conversations on how men and women can negotiate their way through the pandemic as a collective. Data for the paper will be collected through social media (twitter, Facebook, WhatsApp). © 2022 selection and editorial matter, Fortune Sibanda, Tenson Muyambo and Ezra Chitando;individual chapters, the contributors.
Taxpayer Response to Greater Progressivity: Evidence from Personal Income Tax Reform in Uganda

We evaluate a major personal income tax reform in Uganda that came into effect in 2012–13, contributing to the scarce literature on the effects of personal income tax reform on employees’ income in a low-income country in Africa. The reform increased the tax-free lower threshold, increased tax rates for higher incomes, and introduced an additional highest tax band for top 1% of income earners. Using the universe of pay-as-you-earn (PAYE) administrative data from the Uganda Tax Authority, we analyse the impact of the reform on reported labour incomes. In the preferred specification, we find very limited support for behavioural reactions. However, heterogeneity analysis reveals that top-income workers in firms handled by ordinary (as opposed to medium or large taxpayer) offices report lower incomes after the reform. We also find suggestive evidence that part of the response may arise from income shifting. The reform managed to raise more revenue and it also led to a limited reduction in after-tax income inequality.
Therapeutic Plasma Exchange in Guillain Barre Syndrome: An experience of Bangabanhu Sheikh Mujib Medical University, Bangladesh

Background: Therapeutic plasma exchange (TPE) has been used as one of the treatment modalities of neurological diseases. Intravenous Immunoglobulin (IVIG) and Therapeutic Plasma Exchange (TPE)are treatment options in Guillain Barre syndrome (GBS). In developing countries IVIG is not easily available and it is also expensive, TPE is preferred for treatment of GBS as it is affordable. Study on TPE for GBS are scarce here. Most of the study regarding TPE in GBS has been conducted in high –income countries as it is expensive treatment modality. Reports on TPE in GBS is very scared from Bangladesh. Materials and Methods: A retrospective analysis of TPE with a standard hemolysis equipment for the treatment of Guillain Barre syndrome (GBS) was conducted A 50 patients of GBS who received TPE conducted between January 2017 to December 2018 in the department of Transfusion Medicine, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh were analyzed. All patients had underdone at least 2 cycles of plasma exchange. Volume exchanged in each cycle was one plasma volume. Results: Out of 50 cases there were 43 (86%) male and 7 (14%) female. Age range of patients was from 11 – 50 years. Approximately 40% improved clinically of first cycle of PE & 85% after second cycle, 95% after third cycle and 95-100% after 5 cycle. 1(2%) patient died, and 49(98%) patients survived and recovered. Conclusion: The treatment is cost affection in Compassion to IVIG. TPE is and affection, safe and affordable treatment modality for GBS.
Flavonoids and Limonoids Profiles Variation in Leaves from Mandarin Cultivars and Its Relationship with Alternate Bearing

Alternate bearing in citrus trees has been extensively studied as a key feature for citrus growers. Although the genetic and the biochemical process occurring during alternate bearing has been studied extensively, there is a lack of information identifying the presence of metabolic indicators during “on” and “off” years. In citrus plants, leaves play a central role in the metabolic pathway triggering the flowering induction process. To investigate the changes during this transition, a liquid chromatography coupled to tandem mass spectrometry (LC-MS/MS) analysis of the leaf profiles of 20 compounds (17 polyphenols, two limonoids, and one furanocoumarin), in bearing and non-bearing branches arising from four different mandarin genotypes, was performed. The same metabolites were found in all the genotypes at both stages: both limonoids and 11 polyphenols. Using these compounds, the chemotaxonomic differentiation between cultivars was assessed. The levels of flavanones and limonoids showed differences in both bearing stages and the transition from vegetative to flowering could be shown by the activation of the polyphenol biosynthetic pathway, from precursors like naringenin to metabolic end-points such as narirutin and polymethoxyflavones. Narirutin levels showed significant differences between both stages, suggesting it as a possible marker of the physiological status of the branch.
Analysis of the Full-Size Russian Corpus of Internet Drug Reviews with Complex NER Labeling Using Deep Learning Neural Networks and Language Models

The paper presents the full-size Russian corpus of Internet users’ reviews on medicines with complex named entity recognition (NER) labeling of pharmaceutically relevant entities. We evaluate the accuracy levels reached on this corpus by a set of advanced deep learning neural networks for extracting mentions of these entities. The corpus markup includes mentions of the following entities: medication (33,005 mentions), adverse drug reaction (1778), disease (17,403), and note (4490). Two of them—medication and disease—include a set of attributes. A part of the corpus has a coreference annotation with 1560 coreference chains in 300 documents. A multi-label model based on a language model and a set of features has been developed for recognizing entities of the presented corpus. We analyze how the choice of different model components affects the entity recognition accuracy. Those components include methods for vector representation of words, types of language models pre-trained for the Russian language, ways of text normalization, and other pre-processing methods. The sufficient size of our corpus allows us to study the effects of particularities of annotation and entity balancing. We compare our corpus to existing ones by the occurrences of entities of different types and show that balancing the corpus by the number of texts with and without adverse drug event (ADR) mentions improves the ADR recognition accuracy with no notable decline in the accuracy of detecting entities of other types. As a result, the state of the art for the pharmacological entity extraction task for the Russian language is established on a full-size labeled corpus. For the ADR entity type, the accuracy achieved is 61.1% by the F1-exact metric, which is on par with the accuracy level for other language corpora with similar characteristics and ADR representativeness. The accuracy of the coreference relation extraction evaluated on our corpus is 71%, which is higher than the results achieved on the other Russian-language corpora.
Assessing Postoperative Benefits of a Nerve Block: Study Design is Critical [Letter]

By a prospective, randomized, double-blind, placebo-controlled trial including 68 female patients with elective unilateral modified radical mastectomy, Rao et al 1 assessed the effect of preoperative ultrasound-guided thoracic paravertebral block (TPVB) on postoperative quality of recovery and showed that TPVB enhanced the quality of recovery and improve postoperative analgesia. Although the valuable study has been actualized, there are several issues in the design and results of this study that deserve further discussion and clarification.
External Shocks and Their Transmission Channels in Nigeria: A Dynamic Stochastic General Equilibrium Approach

The study examines the sources of external shocks and investigates their transmission channels in Nigeria using the trade-weighted variables from the country’s five top trading partners. Based on the assumption of the small open economy model, the study adopts the New Keynesian Dynamic Stochastic General Equilibrium Model on quarterly data between 1981 and 2018 using the Bayesian estimation technique. Findings from the study reveal that external shocks have a temporary and short-lived effect on the Nigerian economy. In addition, the article shows that oil price, foreign output, and foreign inflation shock have positive impacts on output gap and inflation, while the impact of foreign interest rate shock on the output gap and inflation is negative and not significant. The study also reveals that external shocks collectively explain 86% and 39%of total fluctuations in the output gap and inflation, respectively. Lastly, the study finds that external shocks transmit to the Nigerian economy via different channels. The study, therefore, concludes that terms of trade and exchange rate channels are the dominant transmitters of external shocks in Nigeria. Based on the findings from the study, important policy implications are highlighted.
4PBA reduces growth deficiency in osteogenesis imperfecta by enhancing transition of hypertrophic chondrocytes to osteoblasts

Short stature is a major skeletal phenotype in osteogenesis imperfecta (OI), a genetic disorder mainly caused by mutations in genes encoding type I collagen. However, the underlying mechanism is poorly understood, and no effective treatment is available. In OI mice that carry a G610C mutation in COL1A2, we previously found that mature hypertrophic chondrocytes (HCs) are exposed to cell stress due to accumulation of misfolded mutant type I procollagen in the endoplasmic reticulum (ER). By fate mapping analysis of HCs in G610C OI mice, we found that HCs stagnate in the growth plate, inhibiting translocation of HC descendants to the trabecular area and their differentiation to osteoblasts. Treatment with 4-phenylbutyric acid (4PBA), a chemical chaperone, restored HC ER structure and rescued this inhibition, resulting in enhanced longitudinal bone growth in G610C OI mice. Interestingly, the effects of 4PBA on ER dilation were limited in osteoblasts, and the bone fragility was not ameliorated. These results highlight the importance of targeting HCs to treat growth deficiency in OI. Our findings demonstrate that HC dysfunction induced by ER disruption plays a critical role in the pathogenesis of OI growth deficiency, which lays the foundation for developing new therapies for OI.
The interplay between social interaction quality and wellbeing in military personnel during their initial two-years of service

ABSTRACT This research examined the nature of social interaction profiles in the initial two-years of military service, profile association to early vulnerability to psychological distress, and the association between supervisor interaction qualities in the likelihood of profile membership. Data were collected as part of a larger longitudinal study. Participants who completed key variables at either 3–12 months post-enlistment (N = 5,233; 85.6% male) or 15–24 months post-enlistment (N = 2,162; 79.2% male) were included in the cross-sectional profile analysis of social interaction quality from military and nonmilitary sources. Cross-sectional latent profile analyses and transition analysis were used to investigate the social interaction profiles at each time-point, the effect of leader interactions on movement between profiles, and related psychological distress outcomes. Social interaction quality, and in particular colleague interactions, was predictably associated with psychological distress. Leadership interactions were associated with the nature of colleague social interactions. Greater positive social interactions with leadership was related to a reduced likelihood of experiencing less frequent negative interactions with colleagues. The findings implicate a possible role for supervisors in perpetuating positive or negative colleague interactions. Moreover, a trajectory of vulnerability to psychological distress may start in the initial two-years of military service and emerge from the psychosocial context.
GASCN: Graph Attention Shape Completion Network

Shape completion, the problem of inferring the complete geometry of an object given a partial point cloud, is an important problem in robotics and computer vision. This paper proposes the Graph Attention Shape Completion Network (GASCN), a novel neural network model that solves this problem. This model combines a graph-based model for encoding local point cloud information with an MLP-based architecture for encoding global information. For each completed point, our model infers the normal and extent of the local surface patch which is used to produce dense yet precise shape completions. We report experiments that demonstrate that GASCN outperforms standard shape completion methods on a standard benchmark drawn from the Shapenet dataset.