Miracle-dz/UniFAR-FTUs huggingface dataset:
Are Cookies Based on Soybeans and Aren Safe for Autistic Children?

1) Background: Children with Autism Spectrum Disorder (ASD) have indigestion conditions, so diet in children with ASD is gluten-free and caseinfree diet. Gluten-free and casein-free food products tend to be low in protein. Soy flour with a high protein content is expected to increase the nutritional value (protein) of gluten-free cookies and casein. The authors innovate by adding natural sugar sweeteners using palm sugar in addition to palm sugar has a low glycemic index value. Nutrients in natural sugars also help the process of assimilation into the body. 2) Purpose: This study aims to develop and analyze the nutritional value of soybean flour cookies and palm sugar. 3) Method: This research and development refers to the research and development model of Borg & Gall (1983), consisting of seven steps namely (1) identification and establishing problem solving, (2) conducting preliminary studies and needs analysis, (3) establishing product specifications, (4) developing initial product models, (5) expert trials, (6) review of revised products, and (7) suggestions of utilization, dissemination, and further product development. 4) Results: The results showed that the results of organoleptic tests of soy flour cookies and palm sugar are preferred cookies with a ratio of 50%:50%. The results of the analysis of the nutritional content of selected cookies are 520.07 kcal total energy, 44.58 g carbohydrates, 13.98 g protein, 32.05 g fat, 0.36 g fiber, 0.96 g iron, 6.73 g moisture content, and 2.65 g ash content. 5) Conclusion: Cookies can be consumed autistic children because it is glutenfree and casein-free. Cookies can be served snacks alternative snacks for autistic children according to the needs of the body.
A Review of Emerging Tear Proteomics Research on the Ocular Surface in Ocular Allergy

Simple Summary Ocular allergy is a localised form of allergy occurring on the surface of the eye and surrounding tissues. Typical signs and symptoms of ocular allergy include itching, redness, swelling of the eyelids and inflammation. Emerging studies on ocular allergy have shown that tears collected from ocular allergy sufferers show significantly different protein contents than in healthy populations. Differences in protein contents in tear samples have been hypothesised to be caused by a number of allergy-mediated factors, including long-term inflammation and eye-rubbing. Excessive eye-rubbing due to allergy-associated itch has also been shown to have significant effects on the physical shape of the eye, thereby potentially causing progressive vision problems in ocular allergy sufferers. This review aims to summarise and explore recent findings in ocular allergy protein research. This is to help determine which ocular surface proteins differ between ocular allergy sufferers and healthy controls, and the role each protein may play in the underlying chemistry of ocular allergy. Additionally, potential benefits of expanding the current pool of research into ocular surface proteins in ocular allergy sufferers in terms of diagnosis and treatment of the condition is discussed. Abstract Ocular allergy is an immunoglobulin E-mediated Type I hypersensitivity reaction localised to the ocular surface and surrounding tissues. Primary signs and symptoms of ocular allergy include itching, redness, irritation and inflammation. Eye-rubbing caused by itching has been shown to alter ocular surface protein concentrations in conditions linked to ocular allergy such as keratoconus. In keratoconus, the cornea begins to thin and sag over time, leading to progressive vision loss and blindness in severe conditions. Due to the high incidence of ocular allergy sufferers rubbing their eyes in response to symptoms of itching, the protein landscape of the ocular surface may be significantly altered. Differential protein expression caused by long-term inflammation and eye-rubbing may lead to subsequent changes in ocular surface structure and function over time. This review aims to summarise and explore the findings of current ocular allergy proteome research conducted using techniques such as gel electrophoresis, mass spectrometry and lab-on-a-chip proteomics. Proteins of interest for this review include differentially expressed immunoglobulins, mucins, functional proteins, enzymes and proteins with previously uncharacterised roles in ocular allergy. Additionally, potential applications of this research are addressed in terms of diagnostics, drug development and future research prospects.
Modelling and Seismic Response Analysis of Non-residential Single-storey Existing Precast Buildings in Italy

ABSTRACT Old precast buildings are often characterized by poor detailing that may hamper the structural performance, particularly in the case of earthquakes. This is essentially related to: (i) a limited past knowledge of seismic design and behaviour, also reflected in past building codes; (ii) the evolution of seismic zonation of the Italian territory. The aim of this work is to assess the probabilistic seismic vulnerability with respect to the usability preventing damage and global collapse performance levels of four existing single-story precast buildings designed in accordance with past Italian building codes from 1960s to 1990s in three sites with increasing seismic hazard.
EuclidNets: Combining Hardware and Architecture Design for Efficient Training and Inference

In order to deploy deep neural networks on edge devices, compressed (resource 1 efficient) networks need to be developed. While established compression methods, 2 such as quantization, pruning, and architecture search are designed for conventional 3 hardware, further gains are possible if compressed architectures are coupled with 4 novel hardware designs. In this work, we propose EuclidNet, a compressed network 5 designed to be implemented on hardware which replaces multiplication, wx, with 6 squared difference (x w)2. EuclidNet allows for a low precision hardware 7 implementation which is about twice as efficient (in term of logic gate counts) as 8 the comparable conventional hardware, with acceptably small loss of accuracy. 9 Moveover, the network can be trained and quantized using standard methods, 10 without requiring additional training time. Codes and pre-trained models are 11 available at http://github.com/anonymous/. 12
Attentional fluctuations and the temporal organization of memory

Event boundaries and temporal context shape the organization of episodic memories. We hypothesized that attentional fluctuations during encoding serve as "events" that affect temporal context representations and recall organization. Individuals encoded trial-unique objects during a modified sustained attention task. Memory was tested with free recall. Response time variability during the encoding tasks was used to characterize "in the zone" and "out of the zone" attentional states. We predicted that: 1) "in the zone", vs. "out of the zone", attentional states should be more conducive to maintaining temporal context representations that can cue temporally organized recall; and 2) temporally distant "in the zone" states may enable more recall "leaps" across intervening items. We replicated several important findings in the sustained attention and memory fields, including more online errors during "out of the zone" vs. "in the zone" attentional states and recall that was temporally structured. Yet, across four studies, we found no evidence for either of our main hypotheses. Recall was robustly temporally organized, and there was no difference in recall organization for items encoded "in the zone" vs. "out of the zone". We conclude that temporal context serves as a strong scaffold for episodic memory, one that can support organized recall even for items encoded during relatively poor attentional states. We also highlight the numerous challenges in striking a balance between sustained attention tasks (long blocks of a repetitive task) and memory recall tasks (short lists of unique items) and describe strategies for researchers interested in uniting these two fields.
Adherence to Low-Carbohydrate Diets in Patients with Diabetes: A Narrative Review

Abstract Evidence suggests that low carbohydrate (<130 g/day of carbohydrate) (LCD) and very low carbohydrate, ketogenic diets (typically <50 g/day of carbohydrate) (VLCKD) can be effective tools for managing diabetes given their beneficial effects on weight loss and glycemic control. VLCKD also result in favorable lipid profile changes. However, these beneficial effects can be limited by poor dietary adherence. Cultural, religious, and economic barriers pose unique challenges to achieving nutritional compliance with LCD and VLCKD. We review the various methods for assessing adherence in clinical studies and obstacles posed, as well as potential solutions to these challenges.
Effect of Two Different Plyometric Trainings on Strength, Speed and Agility Performance

Plyometric training (PT) is a popular form of physical conditioning among individuals involved in various dynamic sports to improve physical performances. This study focused on analyzing the effect of plyometric training on improving strength, speed, and agility of students following two kinds of plyometric exercise. It was an experimental research using pretestposttest control group design. A total of 30 students were randomly assigned to three groups: two plyometric training groups of high hurdle jump (HHJ), forward and lateral hurdle jump (FLJ), and one group served as the control (C). Afterward, students in HHJ and FLJ were assigned to respected exercise for five weeks consisted of three sets of each session (total of 16 sessions), with intensity start from 50% to 70%. Pretest and posttest measures were done to obtained data regarding strength, speed, and agility. Data were analyzed using SPSS 20 and were presented as mean and standard deviation. Wilcoxon Signed Rank Test and Kruskall-Wallis were done to compare between-groups difference before and after exercise. Results showed that strength, speed, and agility of students in HHJ and FLJ increased significantly (p<0.05) after 16 sessions of training, while those in control group did not show any different. Between-group difference was only found in strength (p=0.000), which were between HHJ-C (p=0.000) and FLJ-C (p=0.002) pairs. Based on these findings, it was concluded that plyometric training was capable to improve strength, speed, and agility performance. Keywords—forward and lateral jump, hurdle jump, plyometric training, stretch-shortening cycle
VISTA in Soft Tissue Sarcomas: A Perspective for Immunotherapy?

Simple Summary V domain immunoglobulin suppressor of T cell activation (VISTA) has recently been described as a protein expressed on immune cells and tumour cells and a possible target for immunotherapy. We show for the first time that VISTA is broadly expressed across subtypes of soft tissue sarcoma. We found VISTA related to other immunopathological parameters such as tumour-infiltrating lymphocytes and observed improved survival in patients with non-T-cell-inflamed tumours expressing VISTA. Our research supports the notion of VISTA as a potential target for immunotherapy in soft tissue sarcoma. Abstract (1) Background: V domain immunoglobulin suppressor of T cell activation (VISTA) plays a critical role in antitumor immunity and may be a valuable target in cancer immunotherapy. To date, it has never been studied in a large and well-characterised cohort of soft tissue sarcomas (STS). (2) Methods: Using immunohistochemistry, we examined VISTA expression in tumour tissues of 213 high-risk STS. We then analysed whether VISTA was associated with other clinicopathological parameters, including tumour-infiltrating lymphocyte (TIL) counts, programmed death receptor-1 (PD1), programmed death ligand-1 (PDL1), CD3, grading, and long-term survival. (3) Results: We observed VISTA expression in 96 (45%) of 213 specimens with distinct patterns ranging from 26 to 63% for histological subtypes. VISTA was associated with higher grade (G3 vs. G2, p = 0.019), higher TIL counts (p = 0.033), expression of PD1 (p = 0.046), PDL1 (p = 0.031), and CD3+ (p = 0.023). In patients without CD3+ TILs, 10-year survival was higher when VISTA was expressed compared to when there was no VISTA expression (p = 0.013). In a multivariate analysis, VISTA expression was independently associated with prolonged survival (p = 0.043). (4) Conclusions: VISTA is expressed in different STS subtypes and is associated with increased TILs, PD-1, PD-L1, and CD3 expression. Patients with VISTA+ tumours show improved survival. These results may help define future immunotherapeutic approaches in STS.
Regeneration status of trees around Khoh river in Garhwal Himalaya

This paper describes the regeneration status of trees along and away from riverian vegetation of Khoh river area of District Pauri in Garhwal Himalaya. Two sites were studied to examine regeneration status/pattern along the river and away from the river area. Seedling (1129.15 seedlings ha-1), sapling (1010.01seedlings ha-1) and tree density (660 trees ha-1) were greater along the river stretch. The highest and lowest seedling density along the rivarian patch was recorded for Salix teterasperma (162.50 seedlings ha-1) and Toona hexandra (29.17 seedlings ha-1) respectively while the highest and lowest seedling density in the area away from the river was observed for Pyrus pashia (106 seedlings ha-1) and Syzygium cumini (23.33 seedlings ha-1) respectively. The tree species Terminalia alata, Bischofia javanica, Melia azedarch and Dalbergia sissoo along the river and Buchanania lanzan, Pyrus pashia, Lagerstromia parviflora and Bombax ceiba observed away from the river were found without any regeneration. The diameter class showed decreasing trend with increase in size of girth class at both the study sites.
Negative Parenting, Adolescents’ Emotion Regulation, Self-Efficacy in Emotion Regulation, and Psychological Adjustment

This study examines associations between parents’ rejection and control, adolescents’ self-efficacy in their regulation of negative emotions, and maladjustment. Path analyses were employed to test (a) whether adolescents’ dysregulation and self-efficacy regarding anger/sadness regulation mediate the relationship between parental rejection/control and adolescent maladjustment; (b) whether adolescent adjustment mediates the association between parental rejection/control and dysregulation and self-efficacy regarding anger/sadness regulation. Participants included 103 Italian adolescents (Time 1: M age = 15.57; 53% male), their mothers (n = 103), and their fathers (n = 79). Follow up data were assessed one year later (Time 2). At Time 1, adolescent reports of the frequency of mothers’ and fathers’ rejection and control were examined. At Time 2, adolescent-reports of their beliefs about self-efficacy in regulating anger and sadness, as well as anger and sadness dysregulation, were assessed by two methods: questionnaire and mobile ecological momentary assessment. At Time 2, mothers’, fathers’, and adolescents’ reports of adolescents’ aggressive behaviors and depressive problems were also assessed. Maternal rejection was associated with higher one year later aggressive problems, which in turn were associated with higher dysregulation of sadness, and lower self-efficacy in dealing with both anger and sadness. In addition, maternal rejection was associated with higher depressive symptoms one year later, which in turn were associated with lower self-efficacy in dealing with sadness and higher dysregulation of both anger and sadness. Finally, maternal control was associated with higher depressive symptoms, whereas paternal control was associated with lower depressive symptoms.
Factors Impacting the Choice of Seatbelt Use, Accounting for Complexity of Travelers’ Behaviors

Wyoming has one of the highest fatality rates, and a significantly lower rate of seatbelt use in the United States. Thus, this study was conducted with the objective to investigate contributory factors to the choice of drivers’ seatbelt use. Various environmental factors and drivers’ characteristics were considered as it is expected that they account for unseen factors that impact drivers’ choice of buckling up. Although the mixed model has been used extensively for studying the impacts of seatbelt use on the severity of crashes, not many studies have been conducted regarding factors contributing to the choice of seatbelt use itself. In this study, the standard logit model is extended to the mixed model to account for heterogeneity across drivers’ observations. In addition, the standard mixed model was extended to incorporate the random parameters’ heterogeneity in taste based on the means of other observed variables. The results highlighted that moving from the standard logit model to the mixed model, considering heterogeneity in tastes, results in a gain in the model fit, and also an adjustment for the model’s parameters’ estimates. The findings indicated that some of factors impacting the choice of wearing seatbelt include gender, road classification, weather condition, vehicle types, time of driving, vehicle registration and day of the week. Those factors are mainly related to unobserved factors impacting the drivers’ behaviors. For instance, drivers with particular characteristics are expected to own particular vehicle types or drive their vehicles under a particular weather condition.
Socio-environmental and parasitological aspects of waste pickers in Minas Gerais, Brazil

The increase in the generation of Solid Urban Waste causes social, environmental problems and damages to the population's health. Professionals who work in the collection of recyclable waste are exposed to risks of contamination either by toxic elements or pathogenic organisms. The objective of the work was to estimate the types and prevalence of intestinal parasites in waste pickers. A field research was carried out from December 2017 to April 2018 with the voluntary participation of 26 waste pickers belonging to three associations in the municipality of Conselheiro Lafaiete, Minas Gerais, Brazil (CAAE: nº 79937817.7.0000.8122). In addition to the application a socio-environmental questionnaire, each volunteer provided a stool sample for laboratory testing the parasitological examination. Of the 26 survey participants, four (15.4%) had a positive result and were infected by the parasites Giardia lamblia, Entamoeba coli and Iodamoeba butschlii. Among the main factors that can contribute to the infection these waste pickers are the ingestion of untreated water for consumption in addition to reduced access to Personal Protective Equipment (PPE) during waste management. One way to control the presence of parasites would be through health and environmental education actions, periodic parasitological examinations and permanent use of PPE.
The Association of Cholesterol Uptake and Synthesis with Histology and Genotype in Cortisol-Producing Adenoma (CPA)

Cortisol-producing adenoma (CPA) is composed of clear and compact cells. Clear cells are lipid abundant, and compact ones lipid poor but associated with higher production of steroid hormones. PRKACA mutation (PRKACA mt) in CPA patients was reported to be associated with more pronounced clinical manifestation of Cushing’s syndrome. In this study, we examined the association of histological features and genotypes with cholesterol uptake receptors and synthetic enzymes in 40 CPA cases, and with the quantitative results obtained by gas chromatography-mass spectrometry (GC-MS) analysis in 33 cases to explore their biological and clinical significance. Both cholesterol uptake receptors and synthetic enzymes were more abundant in compact cells. GC-MS analysis demonstrated that the percentage of compact cells was inversely correlated with the concentrations of cholesterol and cholesterol esters, and positively with the activity of cholesterol biosynthesis from cholesterol esters. In addition, hormone-sensitive lipase (HSL), which catalyzes cholesterol biosynthesis from cholesterol esters, tended to be more abundant in compact cells of PRKACA mt CPAs. These results demonstrated that both cholesterol uptake and biosynthesis were more pronounced in compact cells in CPA. In addition, more pronounced HSL expression in compact cells of PRKACA mt CPA could contribute to their more pronounced clinical manifestation.
Biogeochemical controls on ammonium accumulation in the surface layer of the Southern 1 Ocean 2 3

1 Department of Oceanography, University of Cape Town, Private Bag X3, Rondebosch, 6 Cape Town, South Africa 7 2 Southern Ocean Carbon and Climate Observatory (SOCCO), CSIR, Rosebank, Cape Town, 8 South Africa 9 3 Department of Conservation and Marine Sciences, Cape Peninsula University of 10 Technology, Cape Town, South Africa 11 4 Marine and Antarctic Research centre for Innovation and Sustainability (MARIS), 12 University of Cape Town, Cape Town, South Africa 13 14 * Corresponding author: smtsha023@myuct.ac. za 15 16
Hierarchical Traffic Flow Prediction Based on Spatial-Temporal Graph Convolutional Network

In recent years, traffic flow prediction has attracted more and more interest from both academia and industry since such information can provide effective guidance for traffic management or driving planning and enhance traffic safety and efficiency. But due to the complicated spatial-temporal dependence in actual roads and the limitation of intersection monitoring equipment, there are still many challenges in spatial-temporal traffic flow prediction. In this paper, we propose a novel hierarchical traffic flow prediction protocol based on spatial-temporal graph convolutional network (ST-GCN), which incorporates both spatial and temporal dependence of intersection traffic to achieve a more accurate traffic flow prediction. Different from existing works, our proposed protocol with the Adjacent-Similar algorithm can also effectively predict the traffic flow of the intersections without historical data. Experiments based on practical traffic data of the city of Qingdao, China demonstrate that our proposed ST-GCN-based traffic flow prediction protocol outperforms the state-of-the-art baseline models. Moreover, as for the intersections without historical data, we can also obtain a good prediction accuracy.