Miracle-dz/UniFAR-FTUs huggingface dataset:
THE ATTRACTIVE DIFFERENCES OF TWO TYPES OF HERBAL MEDICINE FROM ZINGIBERACEAE FRUIT (GOLOBE HALMAHERA)

Herbal medicine is attractive due to its advantages such as its stable condition for a long time packaging about 5 years, and its safety usage because of the natural excellent ingredients. Currently, nanomedicine has been worldwide topic under intensive ongoing research for the effective human health improvement. In this letter, the attractive differences of two types of herbal medicine from zingiberaceae fruit (Golobe Halmahera) namely as rambutan Golobe Halmahera, and original Golobe Halmahera are discussed with their prominent applications as herbal medicine. Moreover, a preliminary work on the healing system of original Golobe Halmahera in reducing a large the number of HIV virus is discussed with its impact in CD4 T cell of lymphocyte. Copyright © 2018, Arend L. Mapanawang. This is an open access article distributed under the creative commons attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Impact of GUT Microbiota on the Type 2 Diabetes Mellitus: NGS Meta-Data Analysis

Metagenomic sequencing is one of the important applications by the Next Generat ion Sequencing (NGS). The metagenome analysis is useful to study the characteristics of composite microbial g roups including uncultivable microbes in various diverse environment such as marine, soil, human body, etc., The gastrointestinal tract contains 10 to 100 times more microbial cells than the whole cells present in our body. Altered gut microbiota has been linked to metabolic diseases such as obesity, diabetes, etc., Certain hypothesis stated that the gut microbiota might be marker for Type 2 Diabetes (T2D) Mellitus. T2D is a complex disorder and it can be influenced by genetic and environmental components. The objective of the study is reanalyzing and explores the microbial population and the functional variation of gut microbiome of the T2D. The four different patient s gut microbiome sample and the healthy control gut microbiome samples were retrieved from the repository NCBI-SRA (BioProject Accession: PRJEB12124), which was sequenced in Beijing Genome Institute. The retrieved data were Meta analyzed and the taxonomy and the functional characteristics of the patient samples were compared with control. The proposed work found that the altered gut microbiota with increase in the abundance of Bacteriodes vulgates and the abundance of bacterial species such as Eubacterium, Lactobacillus, Bifidobacterium and Thetiotomicron were reduced. The manipu lation of the gut microbiome is the emerg ing and novel approach to treat T2D. The research has been pursued in order to influence the amendment in the gut microbiome with caution.
Management of type 2 diabetes mellitus: insights into prescribing trends

Background: Recently, management of type 2 diabetes mellitus (T2DM) has changed with advent of novel agents like DPP4i, SGLT2i and GLP-1 agonist. Of these, DPP4i have emerged as promising agents as monotherapy and as an add-on to metformin for improved glycaemic control. This survey was planned to explore current prescribing trends of physicians of India for the management of T2DM. Methods: This was a prospective, cross sectional, questionnaire-based survey of physicians and endocrinologist across different geographic areas in India. A survey questionnaire consisting of 10 questions related to management of T2DM in real-world clinical settings was prepared, validated in a small group of physicians and then administered to physicians and endocrinologists. Results: Responses from 502 physicians were received. About 60% physicians prefer DPP4i as first add-on to metformin followed by sulfonylurea (SU) (30%). Amongst DPP4i, vildagliptin and sitagliptin were preferred by 48% and 28% physicians respectively as first add-on to metformin. For patients uncontrolled on metformin + SU therapy, 54 % physicians prefer DPP4i as second add-on. Vildagliptin is perceived to have the better efficacy and safety data, as suggested by 40% and 43% physicians respectively. Large number of physicians (48%) were hesitant to prescribe teneligliptin due to insufficient data. SGLT2 inhibitors are preferred as third add-on by 44% physicians. Conclusions: DPP4i are being increasingly preferred by physician as an add-on to metformin. Among DPP4i, the survey revealed that vildagliptin is the most preferred DPP4i as an add-on to metformin possibly owing to its established safety and efficacy data.
Calcitonin as a potential tumour marker for medullary thyroid carcinoma in an 11‐year‐old Spanish Pure Bred gelding with two independent carcinomas

Summary An 11-year-old Spanish Pure Bred gelding was evaluated for progressive weight loss and exercise intolerance. An ante-mortem biopsy and post-mortem histopathological examination of the duodenum revealed a duodenal adenocarcinoma. Furthermore, a medullary thyroid carcinoma of the left thyroid gland and multiple bilateral follicular thyroid adenomas were diagnosed post-mortem. Serum concentration of calcitonin in this case was markedly increased in comparison to two breed and age matched control horses. This case report shows the rare and independent occurrence of two different types of carcinomas in one horse and highlights the diagnostic value of calcitonin measurements for diagnosis of medullary thyroid carcinoma in horses.
Exploring gender-stereotype barriers and advantages of Hong Kong Male Nurses

The purpose of this research is to explore the gender issues and identify the barriers faced by the local male nurses and students in their workplaces or clinical practicum. This project involves individual interviews with male nurses and nursing students and it aims to understand their perceptions towards the gender issues happened in clinical areas and identify the barriers that hindered their learning and career development. A pilot study has been conducted from April to June 2018, four common themes of local gender barriers were identified.
Malnutrition and Morbidity Profile of Under Five Children: A Cross-Sectional Scenario in a Rural Area of Bangladesh

Results: About one-third (33.5%) of the children were stunted in Height for Age Z score. While 23.3% were moderately wasted and 6.5% were severely wasted in Weight for Height Z score. Severely underweight was 8.6%, 20.6% were moderately underweight and 70.8% of the children’s weight was within the normal limit for their age. In MUAC measurement, about one-fourth (21.8%) were moderate acute malnutrition (MAM) and 1.1% were severe acute malnutrition (SAM). Most prevalent disease (45.0%) was the diarrhoeal disease with respiratory tract infection was 32.0% and pneumonia was 18.0%.
Thermophysiological Responses and Heat Tolerance of Saudi Camel Breeds

The present study was conducted to investigate the variation in thermophysiological responses of four Saudi camel breeds. Sixteen dromedary native breeds (Almajaheem, Almaghatir, Alsafrah, Alzargeh) of 4 animals each were used in this study. Exposure of camel to hot summer (40ο C) compared to spring (21ο C) conditions resulted in variable breed-dependent thermophysiological responses. Where, the observed percentage increase in rectal temperature (Tr) and respiratory rate (RR) due to summer heat exposure were highest in Almaghatir and Alsafrah breeds, respectively and lowest in Alzargeh breed. The percentage increase in packed cell volume (PCV) was highest in Almajaheem and Alzargeh and lowest in Alsafrah and Almaghatir. Further, the obtained results indicate that coat color do not influence heat tolerance in camels. Nevertheless, further studies are needed to explore the role of breed variation in the structure of insulating coat and optical properties of hair on thermoregulation and heat tolerance of camels. Keywords—: Breed, Camel, Heat tolerance, Thermoregulation.
Maternal outcome in term premature rupture of membranes

The management of premature rupture of membranes has gone through various cycles of obstetric activity from neglect to immediate intervention. Paralleling these cycles of activity there have been varying degrees of concern about infection According to some studies incidence of premature rupture of membranes is around 5-10%. The time from the rupture of membranes to the onset of contraction is defined as the latent period. The key factor in the fetal and maternal outcome is that the diagnosis of pre-labour rupture of membranes must be established. In most instances either it is obvious from the escape of clear amniotic fluid from cervix or by simple laboratory test like detection of fern pattern/Litmus paper test.
Importance of an Effective Test Suite Minimization Technique in Software Testing

Software testing is an important activity for developing a quality end product. But it is expensive as it requires both time and cost to perform it during development phase and after its delivery. Therefore, it is required to develop some techniques in this direction in order to make software testing a desirable as well as an affordable activity. Hence, in this study we have proposed an effective method that minimizes the size and redundancy from an automated random generated test suite using data clustering technique. The proposed technique compared to other existing techniques achieves a substantial amount of reduction in the size of the test suite without affecting the fault detection capability of the test suite.
CLINICAL EFFICACY OF POST – E-ANAR (PUNICA GRANATUM) IN THE MANAGEMENT OF BAWASEERUL ANF (NASAL POLYPS)-A PRELIMINARY STUDY

Bawaseerul Anf is a growing of excess lahem in the nasal cavity caused by accumulation of Ghaleez khilt (thick humour) infiltrated from the anterior part of the brain and produces nasal obstruction and discharge. This condition corresponds with nasal polyps in modern medicine and is defined as a pedunculated, hypertrophied and oedematous mucosa projecting downwards from the mucous membranes of the nose and paranasal air sinuses into the nasal cavity. It is commonly affecting up to 4% of the population and the recurrence is common with severe disease recurring in up to 10 % of patients. The main objective of this study was to evaluate the efficacy of Punica granatum in the management of Nasal polyps. It was conducted from January to October 2015 in the outpatient department of National Teaching Hospital of Ayurveda, Kotta Road, Borella, Sri Lanka. Diagnosed (n= 30) patients with age group 25-60 years from both sex were selected. The thick decoction of test formula was applied over the polyp mass on the days of 0, 2, 4, 6, 8, 10, 12, 19, and 26. The effectiveness of the study was assessed by using Visual Analog Score (VAS) and Nasal symptom scores (NSS) in 3 follow ups. Data were analyzed by repeated measure of ANOVA with paired ttests. There was significant improvement in subjective parameters; nasal congestion, headache, post nasal drip and mouth breathing (p<0.01). No adverse effects were reported. In this preliminary study the application of the Punica granatum has been found effective in relieving the symptoms of Bawaseerul Anf.
Cancer and cardiovascular disease modelling in North Cyprus.

Age-adjusted mortality in 2004 was essentially unchanged from the early 1990s. At the same time, age-adjusted mortality rates from cardiovascular disease have fallen quite dramatically. Since the causes underlying cancer and cardiovascular disease are likely to be correlated, the decline in mortality rates from cardiovascular disease may be somewhat responsible for the rise in cancer mortality. It is natural to model mortality with more than one cause of death as a competing risks model. Such models are fundamentally unidentified, and it is therefore difficult to get a clear picture of the progress in cancer. This paper derives bounds for aspects of the underlying distributions under a number of different assumptions. Most importantly, I do not assume that the underlying risks are independent, and impose weak parametric assumptions in order to obtain identification. The theoretical contribution of the paper is to provide a framework to estimate competing risk models with interval data and discrete explanatory variables, both of which are common in empirical applications. I use our method to estimate changes in cancer and cardiovascular mortality since 1990. The estimated bounds for the effect of time on the duration until death for either cause are fairly tight and we find that trends in cancer show much larger improvements than previously estimated. For example, we find that time until death from cancer increased by about 10% for NC males and 20% for NC women.
Effect of Ascorbic Acid antioxidant on Soybean (Glycine max L.) plants grown under water stress conditions

Pot experiments were conducted to determine the effect of different water regimes (100%, 80%, 60% and 40% of field capacity, FC) on vegetative growth (plant height, leaf area and plant fresh and dry weights), photosynthetic pigments (chl a, chl b and carotenes), mineral content of leaves (N, P and K), proline content, yield components (pod and seed numbers/plant, seed weight/plant and 100 seed weight), nutritional value of produced seeds (N, P, K and Ca soluble sugars, total carbohydrate, total amino acids and protein contents). The role of ascorbic acid (0, 100, 200 and 300 mg l) in alleviating the effect of water stress was also studied. All growth parameters were significantly reduced with low treatment of FC (60% and 40%) while ascorbic acid, particularly at 100 and 200 mg l , tended to mitigate the harmful effect of high water deficit on growth and chemical constituents in soybean plants. It is suggested that Ascorbic acid could be a promising material used to reduce the harmful effect of water stress on the growth and yield of Glycine max plants grown in Saudi Arabia.
Pharmacological Adherence and Knowledge of Anticoagulated Patients

Objective: To investigate the pharmacological adherence and the knowledge of patients undergoing oral anticoagulation therapy with outpatients. Method: Cross-sectional study with quantitative approach. Results: 222 patients were evaluated, of which 60.8% were classified as non-adherent and 63.1% had inadequate knowledge regarding oral anticoagulant. Non-adherence was related to the longer treatment time (p < 0.001) and to patients with INR values outside the therapeutic range (p = 0.022). Inadequate knowledge was associated with low educational level (p < 0.001), sedentary lifestyle (p = 0.027), shorter outpatient follow-up (p < 0.001), and patients with RNI values outside the therapeutic range (p = 0.012). Conclusion: In view of the results, it is evident the need for health education strategies that address this public, considering individual understanding and pharmacological adherence as crucial in therapy.
Effect of the Strain Rate and Microstructure on Damage Growth in Aluminum

Materials used in soldier protective structures, such as armor, vehicles and civil infrastructures, are being improved for performance in extreme dynamic environments. Nanocrystalline metals show significant promise in the design of these structures with superior strengths attributed to the dislocation-based and grain-boundary-based processes as compared to their polycrystalline counterparts. An optimization of these materials, however, requires a fundamental understanding of damage evolution at the atomic level. Accordingly, atomistic molecular dynamics simulations are performed using an embedded-atom method (EAM) potential on three nano-crystalline aluminum atom systems, one a Voronoi-based nano-crystalline system with an average grain size of 10 nm, and the other two single crystals. These simulations are performed under the condition of uniaxial expansion at several strain rates ranging from 106s−1 to 1010 s−1. Results for the effective stress are discussed with the aim of establishing the role of the strain rate and microstructure on the evolution of the plastic strain and void volume fraction and the eventual loss of stress carrying capability of the atom systems.
ISOLATION AND PURIFICATION OF ANTIBACTERIAL PRINCIPLE FROM AVICENNIA MARINA L IN METHANOL

Objective: The antibacterial principle of Avicennia marina L stem extract was determined by agar well diffusion method followed by GC-MS, 1 H NMR and 13 C NMR. Methods : Methanol was used as the solvent for the isolation of bioactive principle from the stem of Avicennia marina L. Agar well diffusion method was used to screen the antibacterial activity and FRAP method was employed to determine the antioxidant activity for raw and crude extract as well as the purified compound. GC-MS followed by 1 H NMR and 13 C NMR were used to elucidate the compound responsible for the antibacterial and antioxidant activity. Results : The degree of antioxidant and antibacterial activity differs between raw extract, crude extract and the pure compound. The antioxidant activity is more crude extract (p<0.05) and the antibacterial activity is more of pure compound (p<0.05) than the standard antibiotic gentamicin. GC-MS followed by 1 H NMR and 13 C NMR revealed that the compound is 2-propenoicacid, 3-(4-hydroxy-3-methoxyphenyl)- also called ferulic acid. Conclusion : The stem extract in methanol shows potential antibacterial and antioxidant activity. It is due to presence of ferulic acid in methanol extract in 14 th fraction.
Determinants of Customer Satisfaction in Cellular Industry of Pakistan

This paper aims to identify the factors which contribute significantly towards customer satisfaction in the fast growing telecommunication and cellular industry of Pakistan. Low tariff rates, widespread network and good call quality have kept the Pakistani cellular networks’ market growth escalating. Yet, great threats and serious challenges loom for existing clientele management and the attainment of higher growth. The golden solution for this dilemma is the retention of existing clientele via higher customer satisfaction. The aim of this research is to search for the factors which contribute to customer satisfaction for the cellular mobile service companies in Pakistan. A survey was conducted. Preliminarily a qualitative research, followed upon by a questionnaire providing quantitative data were used. Obtained results established a multidimensional assemble for customer satisfaction in the communication sector of Pakistan’s cellular phone organizations hinting towards the conjecture that a cellular phone user’s satisfaction in Pakistan comprises of (i) the tariff, (ii) quality of the call and (iii) services offered to the customer. These findings are in lieu of the previously conducted researches in numerous other countries. Keywords: Customer satisfaction, customer service, call quality, tariff, telecom sector, Pakistan.
Excessive Daytime Sleepiness among Obese People at Obesity Unit, Al-Kindy Medical College, 2018

Background: Excessive daytime sleepiness (EDS) is characterized by persistent sleepiness and often a general lack of energy during the day after apparently adequate or even prolonged nighttime sleep. EDS affects 12% of the normal population and reduces individual’s performance capability and the accuracy of their short-term memory, additionally, it causes learning problems and hazardous events, such as car accidents. Aim of the study: The aim of our study was to find the relationship between EDS and obesity, differences between gender with EDS, and differences between age groups and EDS. Sample and methods: The study was done at the obesity unit, Al-Kindy Medical College. Total 200 people were interviewed, 100 with body mass index equal and more than 30 were considered as an obese group, and the others with body mass index less than 25 was considered as the control group, that are similar to an obese group in the age and gender. We were based on Body mass index (BMI) for assessment of obesity. And sleepiness assessment was based on (Epworth Sleepiness Scale) questionnaire. Results: Obese people with BMI ≥ 30 recorded (54%) of EDS and normal weight people with BMI<25 recorded 33% of EDS. The males group reported 43%, while females reported 44% of EDS. And people with age group younger than 35 years reported a higher percentage of EDS than people equal and older than 35 years. Conclusion: Our study suggests a strong relationship between EDS and obesity, and more increase in BMI; there is a higher risk of EDS that badly affect the daily life activities and productivity in work so we need to be more familiar with these conditions.
Renal Stem Cell

The renal disease is a common problem in human society. End-stage renal disease is a big heath problem in the United States and in all places of the world. Embryonic stem cells, pluripotent derivatives of the inner cell mass of the blastocyst, are the most primitive cell type likely to find application in cell therapy. Their potential to generate any cell type of the embryo makes them to be the most attractive stem cell therapy. It is possible to introduce stem cells into a damaged adult kidney to aid in repair and regeneration. Transdifferentiation offers the possibility of avoiding complications from immunogenicity of introduced cells by obtaining the more easily accessible stem cells of another tissue type from the patient undergoing treatment, expanding them in vitro, and reintroducing them as a therapeutic agent. Adult stem cells may possess a considerable degree of plasticity in the differentiation. Immunoisolation of heterologous cells by encapsulation creates opportunities for their safe use as a component of implanted or ex vivo devices. [Journal of American Science. 2009;5(5):213-222]. (ISSN 1545-4570).
Does the presence of an eschar correlate with severity of scrub typhus infection

Background & Materials and Methods: Â In scrub typhus (ST) the correlation of disease severity to the presence or absence of eschar is not known. We describe the differences between patients with an eschar and those without. Â Results: Â In the 193Â patients, 105Â (56%) had an eschar. Patients with an eschar had a higher incidence of renal failure (18.1% vs. 5.7%; P = 0.01), respiratory system involvement (30.5% vs. 13.6%; P =Â 0.01) and cardiovascular system (CVS) involvement (21.9% vs. 10.2%; P = 0.03). Involvement of the central nervous system, hematological system and gastro-intestinal tract were not statistically significant between the two groups. ST patients with an eschar had significantly higher requirement for noninvasive ventilation (9.1% vs. 1.9%; PÂ =Â 0.04). Requirement of invasive ventilation and inotropic supports were the same in both groups. Â C onclusion: Â The presence of an eschar in patients with ST is associated with a higher incidence of renal dysfunction, CVS and respiratory system involvement and a greater requirement of noninvasive ventilatory support.
Agriculture Communal Labor in the Nuba Mountains *

This paper describes the nature and status of voluntary agriculture communal labor in the agrarian communities of the Nuba Mountains region of Sudan. Communal labor organization is widely used in Africa and worldwide to perform actions that are difficult for an individual to perform alone . It is practiced in different forms and for different objectives. Participant observation was adopted to collect the data needed to meet the objectives of this study. The study results revealed that the communal labor assists to perform tasks that the basic production unitthe family labor, cannot perform alone in the study area. It is also indicated that communal labor today is deteriorating in the face of the expansion of modern agriculture due to peasants’ modernization process and the ongoing war in the region. The study concluded that this form of voluntary labor could be utilized by the NGOs and other community development organizations to mobilize the local community to participate in development activities that needs popular participation such as resources management and utilization. It is also could be utilized to solve labor bottle neck for agricultural development projects.