Miracle-dz/UniFAR-FTUs huggingface dataset:
RMHP_A_305373 2055..2064

1Department of Radiology, Faculty of Medicine, Udayana University/Sanglah General Hospital, Denpasar, Bali, Indonesia; 2Center for Public Health Innovation, Faculty of Medicine, Udayana University, Denpasar, Bali, Indonesia; 3Department of Public Health and Preventive Medicine, Faculty of Medicine, Udayana University, Denpasar, Bali, Indonesia; 4Department of Psychiatry, Faculty of Medicine, Udayana University/ Sanglah General Hospital, Denpasar, Bali, Indonesia Purpose: We aim to study the level of mental health distress and COVID-19 prevention in practice behaviors among general practitioners (GPs) in Bali, Indonesia, as well as their determinants. Methods: We conducted a cross-sectional online survey. Survey recruitment material was disseminated by purposive snowballing through regional professional association as well as research team’s personal acquaintances. The survey measured mental health status by DASS21 questionnaire and practice behavior by a questionnaire based on WHO recommendations for hand hygiene and PPE use during the COVID-19 pandemic. We conducted multivariate analyses to identify independent determinants for mental health and practice behavior. Results: Analyses included 635 (41.75%) of GPs in Bali. Mental health status was relatively good with prevalence of depression, anxiety, and stress of 13.2%, 19.7%, and 11% respectively, lower than previous studies in Indonesia and elsewhere. Practice behavior, however, was not considerably lower with only 65.4% and 32.1% reported consistent hand hygiene and recommended PPE use respectively. Routine optional PPE use was reported by 23.6% of respondents. Long working hours and fear of COVID-19 was identified as detrimental to mental health while consistent hand hygiene improved it. Meanwhile, workplace, work setting, and fear of COVID19, were identified as determinants for PPE use. GPs working in primary health centers and private hospitals were also found to have less adherence to hand hygiene protocols. Conclusion: Our results showed relatively good mental health status along with inadequate infection prevention in practice behavior of GPs in Bali, Indonesia. Intervention should be made to improve practice behavior. Determinants of practice behavior identified in this study could help to pinpoint intervention targets.
Skewing of Initial T Cell Responses Toward the System to Environmental Allergens: Universal Transplacental Priming of the Human Immune

The expression of Th2-skewed immunity against soluble protein Ags present in the normal environment is recognized as the primary cause of allergic inﬂammation in atopics. In contrast, nonallergic normal individuals display low level Th1-skewed immunity against the same Ags (“allergens”), which is perceived as conferring protection against Th2-dependent allergic sensitization. The type of T cell memory that develops against these Ags is currently believed to be the result of complex interactions between environmental and genetic susceptibility factors, which occur postnatally when the naive immune system directly con-fronts the outside environment. The results of the present study challenge this general concept. We demonstrate here for the ﬁrst time that Th2-skewed responses to common environmental allergens, comprising IL-4, IL-5, IL-6, IL-9, and IL-13, are present in virtually all newborn infants and are dominated by high level production of IL-10. Moreover, these responses are demonstrable within 24 h of culture initiation, arguing against a signiﬁcant contribution from covert in vitro T cell priming and/or differentiation. These ﬁndings imply that the key etiologic factor in atopic disease may not be the initial acquisition of allergen-speciﬁc Th2-skewed immunity per se, but instead may be the efﬁciency of immune deviation mechanisms, which in normal (nonatopic) individuals redirect these fetal immune responses toward the Th1 cytokine phenotype. The Journal of Immunology, 1998, 160: 4730–4737. at the time point, after pulse labeling Data as d dpm per designating levels of incorporation (unstimulated) control PCR reactions, employing primers speciﬁc for IL-4, IL-5, IL-9, IFN- g , and b -actin plus Tth plus (Biotech, Western Australia) polymerase, were performed in a programmable thermocycler (Perkin-Elmer, Norwalk, CT). Individual cycle analyses were performed primer cycle numbers were chosen were in the linear phase of the respective am- pliﬁcation reactions. Veriﬁcation of the expected size of the PCR products was obtained analysis in 1.5% agarose gels. of PCR prod- ucts were manually dot-blotted onto nylon membranes and hybridized overnight with biotinylated double-stranded probes; binding was visualized by chemiluminescence using a commercial kit (ECL western blotting re-agents, Amersham International Buckinghamshire, U.K.) Fig. comput-er-assisted densitometric
5,6-Dimethylxanthenone-4-Acetic Acid Disrupting Agent Signals in Response to the Vascular Mouse, but not Human STING, Binds and

Vascular disrupting agents such as 5,6-dimethylxanthenone-4-acetic acid (DMXAA) represent a novel approach for cancer treatment. DMXAA has potent antitumor activity in mice and, despite signiﬁcant preclinical promise, failed human clinical trials. The antitumor activity of DMXAA has been linked to its ability to induce type I IFNs in macrophages, although the molecular mechanisms involved are poorly understood. In this study, we identify stimulator of IFN gene (STING) as a direct receptor for DMXAA leading to TANK-binding kinase 1 and IFN regulatory factor 3 signaling. Remarkably, the ability to sense DMXAA was restricted to murine STING. Human STING failed to bind to or signal in response to DMXAA. Human STING also failed to signal in response to cyclic dinucleotides, conserved bacterial second messengers known to bind and activate murine STING signaling. Collectively, these ﬁndings detail an unexpected species-speciﬁc role for STING as a receptor for an anticancer drug and uncover important insights that may explain the failure of DMXAA in clinical trials for human cancer. The Journal of Immunology , 2013, 190: 000–000.
Exploring prospective student teacher's question on mathematics teaching practice

This research aims to find and describe kinds of questions proposed by prospective students teacher in teaching mathematics practice. The mathematics learning is an activity undertaken by teachers, students and learning environments in learning the mathematical material. The mathematics learning, in this case, is the learning of concept, principal, procedures, and factual mathematics. This research is qualitative research, and the subject is 7th semester students of mathematics at Madura University who was doing their field experience practice. In this study, five prospective students teacher practiced their teaching skill for more less 3-4 meetings. The data was collected from video recording an interview, then the data was analyzed, and triangulation was done. Triangulation result would be used as initial conclusion before the final one is taken. The result of this study is, brainstorm questions emphasized more to the concept understanding, procedures, mathematics principals. Divergent questions are questions which stressing more to the concept of understanding, procedures, and mathematics principle and factual. Convergent questions, brainstorm questions are questions which emphasizing on the understanding of mathematics factual. This focal question is more about justifying or giving students choices in answering questions. This type of question to inquire about procedures and mathematical facts to choose the right one.
Influence of permanent deformations of substructure on ballasted and ballastless tracks performance

The long-term performance of the railway track is an important factor to be taken into account in the design in order to prevent excessive maintenance costs. Therefore, the prediction and control of the permanent deformation of the substructure are key aspects in the analysis and design of railway track structures. In this paper, the influence of permanent deformations of the substructure on ballasted and ballastless tracks is studied through the numerical modelling. It is intended to study the phenomenology involved, namely, the stress path and its influence in the permanent deformation and long-term behaviour. The numerical model is based on the 2.5D formulation, supported by the FEM-PML (Perfect Matched Layers). The evolution of the stress level (and the stress path in particularly) induced by the train is one of the most important factors involved in the permanent deformation laws. Two loading conditions are analysed related to the passage of two trains with different axle loads, geometry and speed: a conventional passenger train (Alfa Pendular) and a freight train.
A Local Approach Toward Multicultural Counseling in Malaysia

Malaysia is a multicultural and multi-religious country. The importance of multicultural counseling has been widely recognized and discussed. Counselors need to be multiculturally-knowledgeable when dealing with multicultural clients. The effectiveness of counseling may likely be improved by integrating Malaysian approaches that are tailored to this country’s traditions and insights, into the current conventional counseling practices. Most of these counseling and psychotherapy theories are based on, and biased towards, the Euro-American culture. Novice counselors in particular frequently reported a lack of skills in dealing with culturally-diverse clients. Multicultural counseling competency is an evolutionary progress that is meant to achieve an effective treatment, and greater inclusion of minorities in mainstream society. Therefore, this paper highlights multicultural counseling competencies and the evolution of counseling in Malaysia. Using narrative method literature review, this paper presents local approaches toward counseling in Malaysia, based on various religions, which are specifically focused on an Islamic approach. This paper then compares and contrasts the local approaches with those of the conventional Western based counseling methods. Some recommendations that merit further investigation are highlighted for future studies.
Groundwater Education: An Investigation of Students' Use of a Groundwater Modeling Tool

Groundwater is a critical component of the global water cycle and standards-based topic within science education. However, students articulate an array of ideas about groundwater systems, including their natural and human elements. One way to support students’ learning about groundwater systems is through the use of data-driven, computer-based modeling tools in technology-enabled science learning environments. To use models to reason productively about groundwater, students must be able to interpret the relationship between the model and the phenomena it represents. Here, we report findings from a study conducted in 7th-grade classrooms (n=209) during implementation of a 3-week curriculum module designed around a data-driven, computer-based groundwater modeling tool – the Hydrogeology Challenge. Students completed a series of tasks using the model to reason about and engage in problem-solving about a realworld, scenario-based water challenge. Here, we focus on how students relate – or map – elements of the model to the components of the authentic water-related phenomena they represent. We conducted quantitative and qualitative analyses of student artifacts and interviews. Findings suggest that students could more easily interpret and understand model elements which represent human dimensions of groundwater systems, such as wells, than they could elements that represent natural dimensions and processes, such as contour lines or groundwater flow direction. These findings provide important insights
an Inflamed Lymph Node Selective Influx of Dendritic Cell Subsets into Mast Cells, Histamine, and IL-6 Regulate the

In response to bacterial stimuli, multiple dendritic cell (DC) populations accumulate within the draining lymph node, thus enhancing op-portunitiesforeffectiveT cell–DC interaction.DCsubpopulations,suchas plasmacytoid,CD8 + ,andCD11b + subsets, have distinct rolesin determining the nature of the immune response. The mechanisms whereby individual DC subpopulations are mobilized and the extent to which these processes are linked to increases in overall lymph node cellularity have not been determined. In the current study, the mechanismsofDC subsetmobilization tothedraining auricularlymph nodewere examinedafterintradermal injectionof Staphylococcus aureus -derivedpeptidoglycan.Usingmastcell-deﬁcientmiceandlocalmastcellreconstitution,plasmacytoidandCD8 + DCresponseswere shown to be mast cell dependent, whereas the CD11b + DC response was not. A histamine H2 receptor-dependent, CXCL9-independent pathway controlled the selective inﬂux of both plasmacytoid and CD11b + DC into the lymph node, but not lymph node cellularity. In contrast, IL-6 was important for the mobilization of CD8 + and CD11b + DC. TNF and IL-1 receptor were dispensable for plasmacytoid, CD11b + , and CD8 + DCresponses. Theseﬁndingsprovide novel opportunities for the selectivemobilization of speciﬁc DC subsets to lymph nodes and demonstrate critical roles for both histamine and IL-6 in this process. The Journal of Immunology , 2010, 184: 000–000. estab-lishment of fully Mouse Cytokine Ab Array III (Norcross, GA) following the manufacturer’s protocol. Image analysis was performed usingQuantityOneSoftware(Bio-Rad,Hercules,CA). Thelistofcytokinesandchemokinesassessedonthisarraywas:Axl,Blymphocytechemokine,CD30L,CD30T,CD40,CRG-2,cutaneousTcell-attractingchemokine,CXCL16,eo-taxin,eotaxin-2,Fasligand,fractalkine,G-CSF,GM-CSF,IFN-g
Small firms and strategic tools for competitive advantage

Strategic management seems to be quite crucial in small organizations and at times it is distinctly different in comparison to large organizations. In most of the cases of small organizations, entrepreneurs or the promoters are sole decision maker. They perceive it to be one man show. We all understand that organization being a separate legal entity must have its strategy in place. The entrepreneur may possess qualities to run his / her organization on the basis of managerial acumen but now-a-days, a person with a distinct and strategic vision is required. The strategic leaders view the market and thus the opportunities and at the same time may meet the challenges and threats. Chances are there, some small enterprises might have developed competence to perform in the times of uncertainty because of their personal attributes but this alone may not be enough. They should gradually cultivate strategic insight and strategic vision that may result in strategic planning. Through this they will be able to meet the challenges of market unevenness and be ready to face other challenges and completion.
CORRECTION OF CUBITUS VARUS DEFORMITY, TECHNIQUES, AN OVERVIEW

: Complex defects of the distal humerus as well as lower arm of either posttraumatic or genetic origination have a considerable negative influence on the functional integrity of the impacted limb. Various techniques of osteotomy have been proposed for the therapy of cubitus varus, which can lead to some complication and most notable aesthetic ones. In this review we highlight available management methods and in details discuss some surgical approaches, their advantages and disadvantages.An electronic search was conducted through; PubMed, EMBASE, CINAHL, SCOPUS, databases, from inception until end of 2019, this search was concerning the Cubitus Varus Deformity. Cubitus varus is one of the most popular difficulty of supracondylar fracture of the humerus it is virtually always second to uncorrected or persistent medial tilting of the distal part of the fracture. It is an avoidable consequence if medial tilt is acknowledged early by cautious medical and radiological evaluation.
Asymptotic and Spectral Analysis of a Model of the Piezoelectric Energy Harvester with the Timoshenko Beam as a Substructure

Mathematical analysis of the well known model of a piezoelectric energy harvester is presented. The harvester is designed as a cantilever Timoshenko beam with piezoelectric layers attached to its top and bottom faces. Thin, perfectly conductive electrodes are covering the top and bottom faces of the piezoelectric layers. These electrodes are connected to a resistive load. The model is governed by a system of three partial differential equations. The first two of them are the equations of the Timoshenko beam model and the third one represents Kirchhoff’s law for the electric circuit. All equations are coupled due to the piezoelectric effect. We represent the system as a single operator evolution equation in the Hilbert state space of the system. The dynamics generator of this evolution equation is a non-selfadjoint matrix differential operator with compact resolvent. The paper has two main results. Both results are explicit asymptotic formulas for eigenvalues of this operator, i.e., the modal analysis for the electrically loaded system is performed. The first set of the asymptotic formulas has remainder terms of the order O ( 1 n ) , where n is the number of an eigenvalue. These formulas are derived for the model with variable physical parameters. The second set of the asymptotic formulas has remainder terms of the order O ( 1 n 2 ) , and is derived for a less general model with constant parameters. This second set of formulas contains extra term depending on the electromechanical parameters of the model. It is shown that the spectrum asymptotically splits into two disjoint subsets, which we call the α -branch eigenvalues and the θ -branch eigenvalues. These eigenvalues being multiplied by “i” produce the set of the vibrational modes of the system. The α -branch vibrational modes are asymptotically located on certain vertical line in the left half of the complex plane and the θ -branch is asymptotically close to the imaginary axis. By having such spectral and asymptotic results, one can derive the asymptotic representation for the mode shapes and for voltage output. Asymptotics of vibrational modes and mode shapes is instrumental in the analysis of control problems for the harvester.
Evaluation of C-reactive protein (CRP) plasma concentration among women during labour and in early puerperium

Objectives: Calculation and analysis of CRP plasma concentration among women during labour and in the second day of puerperium in various clinical situations. Material and methods: 317 participants about estimated due date (EDD) were included to the study and then divided into four groups: Because of early discharge of women from the hospital, as well after vaginal as caesarean delivery, the usefulness of CRP concentration assessment in early puerperium decreases progressively
DDDT_A_268796 5129..5141

1Affiliated Yueqing Hospital, Wenzhou Medical University, Wenzhou 325600, Zhejiang, People’s Republic of China; 2Dong Yang People’s Hospital, Jinhua, Zhejiang 322100, People’s Republic of China; 3Affiliated Jinhua Hospital, Zhejiang University School of Medicine, Jinhua, Zhejiang 321000, People’s Republic of China; 4Ningbo First Hospital, Ningbo 315010, Zhejiang, People’s Republic of China; 5Wenzhou People’s Hospital, Wenzhou, Zhejiang 325000, People’s Republic of China; 6School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou 325000, Zhejiang, People’s Republic of China; 7The Key Laboratory of Geriatrics, Beijing Hospital and Beijing Institute of Geriatrics, Ministry of Health, Beijing 100730, People’s Republic of China
Austin Alzheimer’s and Parkinson’s Disease Depression Preceding Parkinson’s Disease Onset

Parkinson’s disease (PD) is characterized by many non-motor symptoms, some of which appear prior to motor symptom onset. This preceding period is called the preclinical stage, and some symptoms such as depression are observed during this period. In this report, we review the characteristics of depression observed during the preclinical stage of PD. We included studies retrieved from a MEDLINE search of the following: (1) published between 1970 and March 2014, (2) included Medical Subject Heading (MESH) terms including Parkinson’s disease and MESH terms for depression. There were 18 reports that mentioned preclinical depression or depression-related disorders in PD. Most of these reports were case-control studies and a few were cohort studies; there were no prospective studies. PD diagnosis criteria were variable, and some reports did not include these criteria. The diagnosis of depression was also variable, and was based on questionnaires, interviews, medical record reviews, and database searches. Most of these reports indicated that depression preceding PD onset was a significant risk factor for developing PD, with odds ratios of 1.50–3.40. In particular, a history of depression within 5 years of PD diagnosis correlated with PD development. These results should be interpreted with caution because the criteria for depression and PD varied among studies; however, depression preceding the onset of PD may be a risk factor for developing PD. psychological terms meaning depression because the criteria and/or definition of depression as changed over time. This review will focus only on research that examined the association between PD and preceding depression. We determined whether previous review reports existed regarding the association between preclinical depression and PD by executing a MEDLINE search for all reviews of PD and risk factors from 1970 to March 2014. Results of reviews that met the assessment criteria are reported along with additional relevant results. We used the following Medical Subject Heading (MESH) terms in our search: Parkinson’s disease and one or more of the following, including depression, depressive disorder, affective disorder (psychotic), bipolar disorder, and adjustment disorder. We included reports that clearly mentioned preclinical depression in the examined PD cohort; however, clinical diagnostic criteria for depression or PD were irrelevant. If depression was indicated in the report even just a little, we adopted the reports as widely as possible, and the contents were commented respectively.
THE RELATIVE SUSCEPTIBILITY OF CERTAIN OKRA VARIETIES AGAINST THE SPINY BOLLWORM EARIAS INSULANA (BOISD.) (LEPIDOPTERA: NOCTUIDAE)

Fourteen okra varieties were tested in Assiut governorate to estimate their fruit infestation degrees caused by the spiny bollworm Earias insulana (Boisd.) and to determine their susceptibility degrees against this insect pest. Irany, Red base and Balady 4 okra varieties recorded the highest infestation values with an average of 11.92% > 10.40% > 9.13%, respectively. However, Oraby, Balady 5 and Balady 6 okra varieties recorded the lowest values with an average of 6.93% > 6.79% > 6.75%, respectively, as an average of the two successive seasons of 2009 and 2010. The highest infestation was recorded during the last three weeks of August. Dependent on the mean numbers of (Bores + larvae), the tested varieties revealed different susceptibility degrees to the pest. Balady 5 and Balady 6 varieties harboured the lowest numbers and appeared as highly resistant (HR) varieties. The remaining varieties revealed different susceptibility degrees to the pest. Negative correlation was recorded between the numbers of hairs presented on fruit surface of both Balady 5 and Balady 6 varieties and the pest infestation. Therefore, okra varieties that showed some sort of resistance can be included among advanced breeding programs to select new varieties resistance to E. insulana.