Miracle-dz/UniFAR-FTUs huggingface dataset:
Exploring the Use of a Learning-Based Exergame to Enhance Physical Literacy, Soft Skills, and Academic Learning in School-Age Children: Pilot Interventional Study

Background There is ample evidence that most children do not perform enough physical activity (PA). To address this major public health problem, the French government implemented 30 minutes of daily PA (DPA) at schools but did not provide any supplemental resources or concrete guidance. Considering both children’s interest in video games and the need for teachers to complete their curriculum, the use of a learning-based exergame that combines PA and learning appears particularly relevant. Objective The first objective of this study was to evaluate the feasibility of implementing 30 minutes of DPA through exergaming among school-age children. The second objective was to examine the effects of an exergaming program on physical literacy, academic learning, and soft skills (motivation, self-efficacy, and concentration). Methods This interventional study had a pre-post design and used the Play LÜ exergame platform. The study included 79 children with a mean age of 8.9 (SD 1.2) years from grade 2 (7 years old) to grade 5 (11 years old). Play LÜ requires players to throw balls against a wall to reach a target or to activate an object and provides an interactive game area for educational activities linked to specific learning themes. After a 4-session familiarization phase during which the teachers chose to prioritize mathematics learning in 30-minute DPA sessions, students took part in DPA sessions over a period of 3 weeks with Play LÜ and a motor skills circuit behind the LÜ setup to keep them continuously active. All sessions were carried out by PA specialists. Each session started with a warm-up using the Grööve application, continued with main activities promoting mathematics learning adapted to each grade level, and ended with a 3-minute meditation for returning to a calm and serene state using the Gaïa application. Before (T0) and after (T1) the program, students completed a self-evaluation booklet to assess their levels of physical literacy, academic performance, and soft skills. Results The implementation of this exergaming program was welcomed by the school’s administration, teaching staff, and parents. After the program, we observed increased scores for physical literacy (difference +2.6, percentage change +3.6%; W=933.0; P=.002; rrb=−0.39, 95% CI −0.58 to −0.16) and motivation in mathematics (+0.7, +9.8%; W=381.5; P=.005; rrb=−0.44, 95% CI −0.66 to −0.16). In addition, it is important to note that some measures progressed differently across learning levels and age groups. Conclusions The study results indicate positive impacts of learning-based exergaming on physical literacy and motivation in mathematics among school-age children.
Multivisceral Resection for Locally Advanced Gastric Cancer: A Systematic Review and Evidence Quality Assessment

Patients with locally advanced gastric cancer (LAGC) often require multivisceral resection (MVR) of the involved organs to achieve R0 resection and local disease control. The aim of the present study was to systematically review all available literature on the postoperative and long-term outcomes of MVR for gastric cancer. The PubMed database was systematically searched by two independent investigators for studies concerning MVR for LAGC. In total, 30 original studies with 3362 patients met our inclusion criteria. R0 resection was achieved in 67.77% (95% CI, 65.75–69.73%) of patients. The spleen, colon and pancreas comprised the most frequently resected organs in the context of MVR. Pancreatic fistulae (10.08%, 95% CI, 7.99–12.63%), intraabdominal abscesses (9.92%, 95% CI, 7.85–12.46%) and anastomotic leaks (8.09%, 95% CI, 6.23–10.45%) constituted the most common postoperative complications. Using the available data, we estimated the mean 1-year survival at 62.2%, 3-year survival at 33.05%, and 5-year survival at 30.21% for the entire cohort. The survival rates were mainly correlated with lymphatic invasion, tumor size and patient age. Therefore, gastrectomy, together with MVR, is feasible and may offer a survival advantage compared to gastrectomy alone or no other surgical treatment in a selected group of patients. Consequently, both patient and tumor characteristics should be carefully assessed to optimize candidate selection.
Land Subsidence Survey and Monitoring in the North China Plain

The North China Plain has witnessed the most excessive pumping of groundwater in the world and covers the largest subsidence area on the planet. The groundwater level of approximately 70,000 km2 in this region falls below the sea level. Surface subsidence has picked up speed over the last two decades as a result of an increasing demand for groundwater caused by fast economic growth and urbanization, pollution of surface water and construction of skyscrapers. This paper put forward a series of work programming to monitor and control land subsidence mainly caused by groundwater withdrawal in North China Plain. Finally, some progressed achievements on basic facilities construction and general study are presented in this paper.
Nutritional qualities and heavy metals accumulation in grains: A study on lowland irrigated rice with different fertilizer inputs and growing seasons

Integrated and organic nutrient management has become a focal point of current production systems seeking better perspectives on environmental friendliness. The food quality in such a scenario requires special consideration for ensuring safety during consumption. This study was conducted to understand the grain quality of the Bg300 rice variety grown under three fertilizer input systems: conventional (100% N supply with the recommended by the Department of Agriculture (DOA), integrated (50% of N provided with DOA recommended fertilizer + 25% of N supply with organic fertilizer), and 50% of N provided with organic fertilizer in dry tropical irrigated lowland systems in Sri Lanka. The grains were analyzed for proximate composition (moisture content, ash, protein, fat, fiber, and carbohydrate), micronutrients (Fe, Cu, Zn, and Mn), and heavy metals (As, Cd, and Pb). The experiment was arranged as a randomized complete block design and conducted during five seasons, from the 2018-19 wet seasons to the 2020-21 wet seasons. The highest moisture content and carbohydrate content were reported with the organic system. The ash content and protein content significantly (p<0.05) changed with the respective levels of fertilizer in the three input systems. Cadmium and arsenic micronutrients were detected below the permissible level (0.4 and 0.2 ppm), while lead was detected above the permissible level (0.2 ppm). Integrated and organic systems can be used instead of the conventional fertilizer application method without compromising the quality of the rice grain.
SHRIMP zircon ages constraining the depositional chronology of the Hamersley Group, Western Australia

The Mt Bruce Supergroup of Western Australia was laid down between ca 2.8 Ga and ca 2.2 Ga in the Hamersley Basin, unconformably over a basement of the older, granite‐greenstone, component of the Pilbara Craton. The Mt Bruce Supergroup consists of three groups: the Fortescue Group, Hamersley Group and Turee Creek Group in upward sequence. The Hamersley Group, which is divided into eight formations, has a general thickness of ∼2.5 km, and is characterised by major banded iron‐formation (BIF) units. Reported here are SHRIMP U–Pb zircon results (406 grain analyses) from 13 samples taken from the Hamersley Group and near the top of the underlying Fortescue Group. In combination with SHRIMP results previously published from 12 Hamersley Group samples, the present results provide significant new constraints on the depositional chronology of the group, and suggest that the average (compacted) depositional rates of each of the main depositional lithologies (BIF, carbonate, shale) were ∼180 m per million years, 12 m per million years and 5 m per million years, respectively. Some recently published SHRIMP ages from the Joffre Member differ slightly from those that are interpreted from the present data, and it is suggested that the two datasets may be reconciled if non‐zero‐age Pb loss is taken into account. The total body of zircon U–Pb age data from the Fortescue and Hamersley Groups is consistent with a model involving continuous accumulation of basin‐fill for at least 330 million years, from ca 2780 Ma to the top of the Hamersley Group at ca 2449 Ma. The word ‘continuous’ in this context means that there may have been no breaks in deposition longer than 1 million years. However, this model is not proven, and a major challenge for future work is to measure the length of any proposed non‐depositional intervals.
Executive function predictors of science achievement in middle-school students

Cognitive flexibility as measured by the Wisconsin Card Sort Task (WCST) has long been associated with frontal lobe function. More recently, this construct has been associated with executive function (EF), which shares overlapping neural correlates. Here, we investigate the relationship between EF, cognitive flexibility, and science achievement in adolescents. This is important because there are fewer educational neuroscience studies of scientific reasoning than of other academically relevant forms of cognition (i.e., mathematical thinking and language understanding). Eighth grade students at a diverse middle school in the Midwestern US completed classroom-adapted measures of three EFs (shifting, inhibition, and updating) and the WCST. Science achievement was indexed by students’ standardized test scores and their end-of-the-year science class grades. Among the EF measures, updating was strongly predictive of science achievement. The association between cognitive flexibility and science achievement was comparatively weaker. These findings illuminate the relationship between EF, cognitive flexibility, and science achievement. A methodological contribution was the development of paper-and-pencil based versions of standard EF and cognitive flexibility measures suitable for classroom administration. We expect these materials to help support future classroom-based studies of EF and cognitive flexibility, and whether training these abilities in adolescent learners improves their science achievement.
Sodalite-group minerals from the Somma - Vesuvius volcanic complex, Italy: a case study of K-feldspar-rich xenoliths

Abstract Sodalites and sulfatic sodalites in holocrystalline K-feldspar-rich ejecta from the Somma-Vesuvius volcanic complex, Italy, have been characterized by combined chemical, structural and spectroscopic analyses. Sodalite has a relatively homogeneous chemical composition, with the ubiquitous presence of CO2-3 and H2O/OH-. The sulfatic sodalites are isomorphous and have cage structures which can contain a wide variety of anions, molecular species and cations. Molecular CO2 and H2O/OH- are present in sulfatic sodalites, instead of the CO2-3 anions that are present in sodalite sensu stricto. The cell dimensions of the all of the studied sodalite samples are very similar, the sulfatic sodalite cell dimensions are more variable. Structure refinement of a distinctly green sample confirms the P4̅3n space group. Metasomatic magma-derived fluids that are rich in H2O, CO2, Cl and S are believed to be responsible for the genesis of the relatively late-stage phases which form the ejecta containing the sodalite-group minerals.
Recent Discovery of Handaxes Associated with Tektites in the Nanbanshan Locality of the Damei Site, Bose Basin, Guangxi, South China

최근에 발견된 176점의 석기에 대해서 알리고자 하는데, 이 중에는 주먹도끼도 2점이 들어 있는데, 이들은 남중국의 보세 분지의 다메이유적의 난반샨지점의 유지앙 강 제4단구 퇴적층에서 발견되었다. 이들의 특징은 보세 분지의 다른 유적에서 발견된 구석기시대 석기들과 동일하다. 주먹도끼, 주먹찌르개와 다른 석기들은 155개의.
Features and Causes of Indosinian Intracontinental Structures in the Xuefengshan Precambrian Basement and Its Neighboring Regions

The eastern South China continental block can be subdivided into the Yangtze block and the Cathaycian block.The Xuefengshan intracontinental tectonic system is one important part of the Yangtze block.The distribution of the unconformities between Triassic and Jurassic in the Xuefengshan tectonic system reveals four kinds of contact interfaces,including high-angle unconformity,low-angle unconformity,disconformity and conformity and becoming younger and younger to the west.Then the characteristics of Indosinian folds are also subdivided into two directions of fold axial traces in the South China,i.e.northeast-and northwest-striking folds,which were superimposed by the N-S-trending thrusts.The authors proposed that the longitudinal arcuate and northeastward structures in the Xuefengshan intracontiental tectonic system result from a control of different block borders under the same stress field as the previous one.The first-generation NEE-striking folds are rotated from the earlier NNE-striking folds due to late block rotating.The second-generation NNE-striking folds superimpose the NEE-striking folds.The intracontinental shortening between the Yangtze and Cathaysian blocks was earlier than the collision of the South China block with the Qinling-Dabie micro-continent.The Yangtze block and the Qinling-Dabie micro-continent had rotated in Early Indosinian orogeny.these resulted in a difference between those earlier structural lines formed in Early Triassic,the perpendicular relation to these structural lines was at last remained although they underwent small rotation between the Yangtze and Cathaysian blocks.
Cenozoic Volcanism of Southeast Asia

This paper presents an analysis of published and our own data on the geochemistry and isotopic sys- tematics of the Cenozoic volcanic complexes of southeastern China, Vietnam, and Thailand and the adjoining East China and South China seas. Three large periods of volcanic activity were distinguished: Early Tertiary, Miocene, and Pliocene-Quaternary. The first period was characterized by the development of potassic basalt (absarokites and cocites in Vietnam) and tholeiitic bimodal (basalts and trachytes in southeastern China) volca- nism, and the subsequent periods were dominated by intraplate-type tholeiitic and alkaline volcanism and minor occurrence of bimodal tholeiitic magmatism (basalts and rhyolites of the Okinawa Trough). The Ceno- zoic magmatic and geodynamic events were correlated over the region. It was shown that lateral and temporal variations in the compositions of the Miocene and Pliocene-Quaternary rocks reflect strong isotopic and geochemical heterogeneity of deep-seated magma sources.
Adjunctive Therapeutics in the Management of Cardiopulmonary Resuscitation: A Narrative Literature Review

Nearly 565,000 patients will suffer from prehospital and inpatient cardiac arrest in the United States per annum. Cardiopulmonary resuscitation and all associated interventions used to achieve it remain an essential focus of emergency medicine. Current ACLS guidelines give clear instructions regarding mainstay medications such as epinephrine and antiarrhythmics; however, the literature remains somewhat controversial regarding the application of adjunctive therapeutics such as calcium, magnesium, sodium bicarbonate, and corticosteroids. The available data acquired in this field over the past three decades offer mixed pictures for each of these medications on the effects of core metrics of cardiopulmonary resuscitation (e.g., rate of return of spontaneous circulation, survival-to-hospitalization and discharge, 24 h and 30 d mortality, neurological outcome), as well as case-specific applications for each of these interventions (e.g., polymorphic ventricular tachycardia, electrolyte derangements, acidosis, post-arrest shock). This narrative literature review provides a comprehensive summary of current guidelines and published data available for these four agents and their use in clinical practice.
INVENTORY AND IDENTIFICATION OF PARASITOID EGGS AND LARVAE OF Spodoptera frugiperda (LEPIDOPTERA: NOCTUIDAE)

Spodoptera frugiperda is an invasive pest that invades Indonesia and attacks maize crops. Suppressing the development of pests needs various control methods, including biological control through the application of natural enemies. Therefore, this study was carried out to prepare the inventory and identified the natural enemies, especially parasitoids of S. frugiperda . This study was conducted on farmer's land in Purwobinangun Village, Sei Bingai Sub-District, Langkat District, North Sumatra Province, Indonesia. It was performed using a survey method by taking samples of eggs and larvae of pests S. frugiperda on maize through a purposive sampling (intentional sampling) method. The sampling was carried out on intercropping and monoculture maize crops. The collected eggs and larvae of S. frugiperda were taken to the Agriculture Faculty, Universitas Sumatera Utara plant pest laboratory to be reared until the parasitoids emerged. The result showed that two species of parasitoids were obtained namely Telenomus sp. and Trichogramma sp. , with a level of parasitization of egg reached 80% for intercropping and 62.67% for monoculture. The larval parasitoids were obtained from three subfamilies of parasitoids, namely Cheloninae, Microgastrinae, and Campopleginae, with a level of parasitization around 13.2% for monoculture and 9.2% for intercropping.
A refined mapping of Arctic lakes using Landsat imagery

Effective mapping of water bodies at regional scales is a challenge with respect to the description and monitoring of hydrological, climatic, and landscape processes. In a region as sensitive to climate change as the Arctic, inaccurate representation of lake cover has probably led to underestimation of the role of lakes as landscape constituents and thus of their contribution to biochemical cycles. To estimate lake cover reliably (and perhaps also its change through time), the scientific community necessitates techniques for mapping water bodies using satellite sensors that include rich historical data sets and have sufficiently fine spatial resolution. Here we applied a density-slicing detection technique to 617 cloud-free Landsat images for the summer months 2006–2011. We developed a comprehensive database of Arctic lakes with a detection accuracy of 80% and examined spatial patterns of lake distribution in relation to landscape properties. We mapped about 3,500,000 lakes; these cover nearly 6% of the Arctic land surface (about 400,000 km2) and are typically small (<0.1 km2). Lake density and lake fraction analyses show that lakes are most common in lowland permafrost areas with tundra vegetation. The method described here can also be used to map and monitor lake cover at regional to hemispheric scales and to monitor changes in lake cover over time.
U.S. Consumers’ Tree Nut Food Safety Knowledge, Perceptions, and Handling Practices across Demographic Groups

Tree nuts are often perceived as presenting a low risk for foodborne illness, despite their association with several foodborne outbreaks and recalls in recent years. An online survey was designed to assess how consumers’ food safety knowledge, perception of risks and benefits, and preferred sources for food safety information influence their tree nut handling behavior. Participants (n = 981) who soaked tree nuts or prepared nut-based dairy analogs (NBDAs) at home completed the survey. Their responses indicated insufficient knowledge about potential contaminations of tree nuts. Only 25% of participants had heard of a tree nut-related outbreak or recall. Few (30%) participants perceived a risk of contracting a foodborne illness from tree nuts. The participants were more concerned with the health benefits than potential microbial risks of raw tree nuts and preferred government agencies for tree nut food safety information. Based on a cluster analysis, demographics with lower food safety knowledge and risk perceptions (ages 18–24 or 45 and above, female, suburban and rural communities, have less than a bachelor’s degree, and earned less than USD 100,000 annually) tended to engage in risky tree nut handling practices (p < 0.05). The findings of this study support the development of audience-targeted food safety extension materials for tree nuts.
Ravulizumab in Myasthenia Gravis: A Review of the Current Evidence

Abstract The terminal complement C5 inhibitor ravulizumab was engineered from the humanized monoclonal antibody eculizumab to have an extended half-life and duration of action. It binds to human terminal complement protein C5, inhibiting its cleavage into C5a and C5b, thus preventing the cascade of events that lead to architectural destruction of the postsynaptic neuromuscular junction membrane by the membrane attack complex, and consequent muscle weakness in patients with anti-acetylcholine receptor (AChR) antibody-positive generalized myasthenia gravis (gMG). The 26-week randomized, placebo-controlled period (RCP) of the phase 3 CHAMPION MG study demonstrated the rapid efficacy of ravulizumab in reducing MG symptoms. Weight-based dosing of ravulizumab every 8 weeks provided sustained efficacy, in terms of patient-reported (Myasthenia Gravis–Activities of Daily Living) and clinician-reported (Quantitative Myasthenia Gravis) endpoints in patients with anti-AChR antibody-positive gMG. Pharmacokinetic and pharmacodynamic analyses showed therapeutic serum ravulizumab concentrations (>175 µg/mL) were achieved immediately after the first dose and were maintained throughout 26 weeks, irrespective of patient body weight; inhibition of serum free C5 was immediate, complete (<0.5 μg/mL), and sustained in all patients. Interim results from the open-label extension (OLE) showed that after 60 weeks, efficacy was maintained in patients continuing on ravulizumab. Rapid and sustained improvements in efficacy, similar to those seen in patients initiating ravulizumab in the RCP, were observed after initiation of ravulizumab treatment in patients who switched from placebo in the RCP to ravulizumab in the OLE. The findings from the RCP and OLE support ravulizumab’s favorable safety profile. In conclusion, ravulizumab has a simple weight-based administration and long dosing interval. Its targeted mechanism of action without generalized immunosuppression is reflected in its rapid onset of symptom improvement, sustained efficacy and good safety profile in the treatment of patients with anti-AChR antibody-positive gMG.
Evaluation of factors associated with bulk milk somatic cell count and total plate count in Indonesian smallholder dairy farms

Increasing milk quality in smallholder dairy farms will result in a greater quantity of milk being delivered to milk collection centers, an increased milk price for farmers and consequently an improved farmers’ livelihood. However, little research on milk quality has been performed on smallholder farms in Southeast Asia. The objective of this study was to identify risk factors associated with somatic cell count (SCC) and total plate count (TPC) in Indonesian smallholder dairy farms. One dairy cooperative in West Java, Indonesia was selected based on its willingness to participate. All 119 member farmers in the cooperative, clustered in six groups, were interviewed and a bulk milk sample from all farms was collected in April 2022. Risk factors associated with dairy farms’ SCC and TPC were investigated using multivariable population-averaged generalized estimating equations (GEE) models. The mean geometric SCC and TPC from these farms were 529,665 cells/mL of milk and 474,492 cfu/mL of milk, respectively. Five risk factors including manure removal frequency, receiving mastitis treatment training, washing the udder using soap, number of workers, and ownership of the pasture area were associated with SCC. Two risk factors, manure removal frequency and dairy income contribution, were associated with TPC. These findings can therefore be used as a starting point to improve udder health and milk quality in Indonesia and other countries where smallholder farmers play a significant role in milk production.