Miracle-dz/UniFAR-FTUs huggingface dataset:
Innovative Enterprises Development and Employees’ Knowledge Sharing Behavior in China: The Role of Leadership Style

Leadership is generally considered helpful for team knowledge sharing. However, differences in the influence of different leadership styles on team knowledge sharing mechanism is still unclear. To understand different leadership style foster team knowledge sharing, this study focuses on leader–follower trust during team interactions. From the perspective of leadership as social problem solving, we argue that transformational leadership and authoritative leadership are different linked to team knowledge sharing. Through the collection of a sample of 791 valid questionnaires in China, we used the structural equation model to test the theoretical model. Results showed that: (1) Transformational leadership was positively linked to explicit and implicit knowledge sharing, while authoritative leadership was positively linked to explicit knowledge sharing. (2) Trust tendency mediates the relationship between authoritative leadership and knowledge sharing. (3) Supportive and bureaucratic culture moderate the influence of trust tendency on implicit knowledge sharing, such that the positive relationship is stronger for the low-quality of supportive culture and the high-quality of bureaucratic culture. Finally, The study’s implication for theory and practice were discussed, its limitations were identified, and directions for future research were suggested.
Impact of School Closure Due to COVID-19 on the Social-Emotional Skills of Japanese Pre-school Children

Objective: This study examines the impact on the social-emotional skills of Japanese pre-school children from downsizing of school activities in conjunction with voluntary school closures due to the first wave of COVID-19, in 2020. Methods: Participants included 32 children aged 4–5 years old from three pre-schools in Tokyo, Japan, where strict lockdown was not implemented and voluntary school closure was recommended. Child social-emotional skills was assessed by classroom teachers using Devereux Student Strengths Assessment mini (DESSA-mini) three times: November 2019, January 2020 (before the COVID-19), and March 2020 (during the first COVID-19 wave). All pre-schools implemented voluntary school closures from March 2nd, and two schools (school A and B) canceled school recitals, while one school (school C) allowed for it to be held on March 4th, with precautions in place to prevent the spread of infection. Repeated measures ANOVA were performed to examine the difference between the T scores of the DESSA-mini three pre-schools before and during the COVID-19 pandemic. Results: In school C, children showed stable T scores of the DESSA-mini, whereas children in school A and B showed lower T scores of the DESSA-mini during COVID-19 than before it started. The interaction effects between time and pre-schools were found (F = 7.05, p < 0.001). Conclusion: Our findings suggest that school recitals in pre-schools were important to maintaining children's social-emotional skills during the COVID-19 pandemic.
Identification of a Ferroptosis-Related Long Noncoding RNA Prognostic Signature and Its Predictive Ability to Immunotherapy in Hepatocellular Carcinoma

Background: Immune checkpoint blockers (ICBs) are increasingly being used to treat patients with advanced hepatocellular carcinoma (HCC), but only a third of these patients are sensitive to ICBs. Emerging evidence suggests that ferroptosis could be a novel target for antitumor treatment, and combined treatment with ferroptosis inducers might enhance sensitivity to immunotherapy. However, there is a lack of information on the crosstalk between ferroptosis-related lncRNAs and anti-tumor immunity. Therefore, we aim to explore prognostic value of ferroptosis-related lncRNAs and clarify potential role in ICBs of HCC. Methods: We obtained mRNA and lncRNA expression data from two independent cohorts (TCGA and GEO database). Univariate Cox, the least absolute shrinkage and selection operator (Lasso) algorithm and multivariate Cox analysis were used to construct a lncRNA signature, which was evaluated using the area under the receiver operating characteristic curve (AUC) and Kaplan–Meier curves. Tumor-infiltrating cell (TIC) profiling and the tumor immune dysfunction and exclusion (TIDE) algorithm were used to validate the signature model and immunotherapy. Finally, we adopted RT-PCR assay to evaluate the differential expression of lncRNAs in HCC tissues in our hospital. Results: The ferroptosis-related lncRNA signature included five lncRNAs, most of which were positively correlated with clinical stage and grade. The signature could stratify patients into two risk groups, with the high-risk group associated with a shorter overall survival (OS, p < 0.05) in TCGA-LIHC and GSE76427. Besides, the AUCs of the 1-, 3-, and 5-years OS were 0.772, 0.707, and 0.666, respectively. Gene set enrichment analysis (GESA) of lncRNAs revealed enrichment of oncogenic and immune-related pathways. The TIC profiling indicated a close correlation between the signature and immune cells. Furthermore, the high-risk group had a better response to immunotherapy than low-risk group. RT-PCR demonstrated these five lncRNAs were upregulated in cancerous tissue than normal tissues. Conclusions: The ferroptosis-related lncRNA signature could accurately predict the OS of HCC patients and may serve as an independent clinical factor for patients’ outcomes. Ferroptosis-related lncRNAs may remodel the tumor microenvironment (TME) and affect the anti-cancer ability of ICBs, and therefore, could potentially act as an indicator for the response to immunotherapy in HCC.
The Nucleolar Localization Signal of Porcine Circovirus Type 4 Capsid Protein Is Essential for Interaction With Serine-48 Residue of Nucleolar Phosphoprotein Nucleophosmin-1

Porcine circovirus type 4 (PCV4) is an emerging etiological agent which was first detected in 2019. The nucleolar localization signal (NoLS) of PCV4 Cap protein and its binding host cellular proteins are still not elucidated. In the present study, we discovered a distinct novel NoLS of PCV4 Cap, which bound to the nucleolar phosphoprotein nucleophosmin-1 (NPM1). The NoLS of PCV4 Cap and serine-48 residue at the N-terminal oligomerization domain of NPM1 were necessary for PCV4 Cap/NPM1 interaction. Furthermore, the charge property of serine residue at position 48 of the NPM1 was crucial for its oligomerization and interaction with PCV4 Cap. In summary, our findings show for the first time that the PCV4 Cap NoLS and the NPM1 oligomerization determine the interaction of Cap/NPM1.
The Study of Security Priming on Avoidant Attentional Biases: Combining Microsaccadic Eye-Movement Measurement With a Dot-Probe Task

Microsaccades are small fixational eye movements that have shown to index covert attentional shifts. The present experiment combined microsaccades with performance measures from a dot-probe task to study influences of attachment security priming on the attentional biases of individuals high in attachment avoidance. Security priming is an experimental manipulation aimed at boosting felt security. Using a randomized, mixed design, we measured differences in attentional vigilance toward angry and neutral faces as a function of priming (neutral vs. secure) and attachment avoidance. Individuals high in avoidance habitually tend to withdraw from, or otherwise dismiss, emotionally salient stimuli. Here, we operationalized attentional withdrawal based on both task performance in the dot-probe task and microsaccadic movements. In addition, unlike previous studies where priming salience for the individual participant has been unclear, we used a standardized narrative method for attachment script assessment, securing an indication of how strongly each participant was primed. Dot-probe data significantly captured the link between avoidance and attentional disengagement, though from all facial stimuli (angry and neutral). Although microsaccadic movements did not capture avoidant attentional disengagement, they positively correlated to dot-probe data suggesting measurement convergence. Avoidance was associated with weaker security priming and no overall effect of priming on attention was found, indicating a need for further exploration of suitable priming methods to bypass avoidant deactivation. Our results provide a first indication that, as an implicit looking measure, microsaccadic movements can potentially reveal where early attention is directed at the exact moment of stimulus presentation.
Relating Cultural Distance to Self-Other Agreement of Leader–Observer Dyads: The Role of Hierarchical Position

Multisource feedback is important for leadership development and effectiveness. An important asset of such feedback is that it provides information about the self-other agreement between leaders and observers. Self-other agreement relates to several positive individual, dyadic, and organizational outcomes. Given the increasingly intercultural context in organizations, it is imperative to understand whether and how cultural distance between leaders and observers relates to self-other agreement. We hypothesize that cultural distance within leader-observer dyads is negatively associated with self-other agreement. Moreover, we expect that this relationship is stronger for leader-superior than leader-subordinate dyads. We use a unique multi-cultural dataset of 7,778 leaders (52 nationalities) rated by 22,997 subordinates (56 nationalities) and 10,132 superiors (54 nationalities) to test our hypotheses. Results confirm that cultural distance is negatively associated with self-other agreement; we show that this relationship is driven by increased self-ratings and by reduced other-ratings. In addition, we find that these results are more pronounced for leader–superior than for leader–subordinate dyads. Implications for the theory and practice of self-other agreement and multisource feedback are discussed.
Effect of Divergent Feeding Regimes During Early Life on the Rumen Microbiota in Calves

The objective of this study was to determine whether divergent feeding regimes during the first 41 weeks of the life of a calf are associated with long-term changes in the rumen microbiota and the associated fermentation end-products. Twenty-four calves (9 ± 5 days of age) were arranged in a 2 × 2 factorial design with two divergent treatments across three dietary phases. In phase 1 (P01), calves were offered a low-milk volume/concentrate starter diet with early weaning (CO) or high-milk volume/pasture diet and late weaning (FO). In phase 2 (P02), calves from both groups were randomly allocated to either high-quality (HQ) or low-quality (LQ) pasture grazing groups. In phase 3 (P03), calves were randomly allocated to one of two grazing groups and offered the same pasture-only diet. During each dietary phase, methane (CH4) and hydrogen (H2) emissions and dry matter intake (DMI) were measured in respiration chambers, and rumen samples for the evaluation of microbiota and short-chain fatty acid (SCFA) characterizations were collected. In P01, CO calves had a higher solid feed intake but a lower CH4 yield (yCH4) and acetate:propionate ratio (A:P) compared with FO calves. The ruminal bacterial community had lower proportions of cellulolytic bacteria in CO than FO calves. The archaeal community was dominated by Methanobrevibacter boviskoreani in CO calves and by Mbb. gottschalkii in FO calves. These differences, however, did not persist into P02. Calves offered HQ pastures had greater DMI and lower A:P ratio than calves offered LQ pastures, but yCH4 was similar between groups. The cellulolytic bacteria had lower proportions in HQ than LQ calves. In all groups, the archaeal community was dominated by Mbb. gottschalkii. No treatment interactions were observed in P02. In P03, all calves had similar DMI, CH4 and H2 emissions, SCFA proportions, and microbial compositions, and no interactions with previous treatments were observed. These results indicate that the rumen microbiota and associated fermentation end-products are driven by the diet consumed at the time of sampling and that previous dietary interventions do not lead to a detectable long-term microbial imprint or changes in rumen function.
The Role of Bacterial-Derived Aromatic Amino Acids Metabolites Relevant in Autism Spectrum Disorders: A Comprehensive Review

In recent years, the idea of the gut microbiota being involved in the pathogenesis of autism spectrum disorders (ASD) has attracted attention through numerous studies. Many of these studies report microbial dysregulation in the gut and feces of autistic patients and in ASD animal models. The host microbiota plays a large role in metabolism of ingested foods, and through the production of a range of metabolites it may be involved in neurodevelopmental disorders such as ASD. Two specific microbiota-derived host metabolites, p-cresol sulfate and 4-ethylphenyl sulfate, have been associated with ASD in both patients and animal models. These metabolites originate from bacterially produced p-cresol and 4-ethylphenol, respectively. p-Cresol and 4-ethylphenol are produced through aromatic amino acid fermentation by a range of commensal bacteria, most notably bacteria from the Clostridioides genus, which are among the dysregulated bacteria frequently detected in ASD patients. Once produced, these metabolites are suggested to enter the bloodstream, pass the blood–brain-barrier and affect microglial cells in the central nervous system, possibly affecting processes like neuroinflammation and microglial phagocytosis. This review describes the current knowledge of microbial dysbiosis in ASD and elaborates on the relevance and synthesis pathways of two specific ASD-associated metabolites that may form a link between the microbiota and the brain in autism. While the two discussed metabolites are promising candidates for biomarkers and (nutritional) intervention targets, more research into the role of these metabolites in ASD is required to causally connect these metabolites to ASD pathophysiology.
Impact of Green Human Resource Management on Service Recovery: Mediating Role of Environmental Commitment and Moderation of Transformational Leadership

Greening of the hotel industry can be achieved through employees' green service recovery performance (GSRP) of employees to determine environment-friendly or unfriendly issues driven by environmental commitment and green human resource management (HRM) practices. This article attempts to resolve the research problem by analyzing the moderating effect of transformational leadership style on green HRM practices with employee environmental commitment (EEC) and GSRP in the hotel industry. The present study recruited 489 front-line employees (FLE) and their 24 direct managers. The research results reveal that environmental commitment of employee mediates the relationship between green HRM practices and GSRP. Moreover, the transformational leadership style moderates the relationship between green HRM practices and employee environmental commitment in the hotel industry. The study has critical insights and implications for hotel managers and theory.
Assessment of the training program for Versius, a new innovative robotic system for use in minimal access surgery

Objectives The Versius surgical system has been developed for use in robot-assisted minimal access surgery (MAS). This study aimed to evaluate the effectiveness of the Versius training program. Design A 3.5-day program following 10 hours of online didactic training. Participants were assessed during the technical training using the Global Evaluative Assessment of Robotic Skills (GEARS). Setting Dry box exercises were conducted in classrooms, and wet lab sessions simulated an operating room environment using cadaveric specimens. Participants Seventeen surgical teams participated; surgeons represented general, colorectal, obstetrics/gynecology, and urology specialties. All surgeons had previous laparoscopic MAS experience, while experience with robotics varied. Main outcomes measures Participants were scored on a five-point Likert Scale for each of six validated GEARS domains (depth perception, bimanual dexterity, efficiency, force sensitivity, autonomy, and robotic control). Additional metrics used to chart surgeon performance included: combined instrument path length; combined instrument angular path; and time taken to complete each task. Results Participants demonstrated an overall improvement in performance during the study, with a mean GEARS Score of 21.0 (SD: 1.9) in Assessment 1 increasing to 23.4 (SD: 2.9) in Validation. Greatest improvements were observed in the depth perception and robotic control domains. Greatest differences were observed when stratifying by robotic experience; those with extensive experience consistently scored higher than those with some or no experience. Conclusions The Versius training program is effective; participants were able to successfully operate the system by program completion, and more surgeons achieved intermediate-level and expert-level GEARS scores in Validation compared with Assessment 1.
An Exploratory Study of Language Use and Preferences among Nursing Lecturers and Students at Mzuzu University in Malawi

This article reports on the insights gained from multilingual nursing lecturers and students at Mzuzu University in Malawi on the languages they use and prefer in a classroom setting. Research (Setati, Chitera and Essien, 2009; Chowdhury 2012) has found that both lecturers and students in multilingual and multicultural settings favour code-switching practices in the classroom setting. Code-switching is, therefore, an important phenomenon, which researchers should continue exploring because of the several distinctive attributes associated with it. The study adheres to qualitative and quantitative designs through the use of a questionnaire and follow-up interviews as methods of data collection. The results reveal that both lecturers and students favour code-switching from English to Chichewa during lectures. From both lecturers’ and students’ perspectives, code-switching helps to translate and clarify difficult concepts. It also helps to prepare students for the nursing profession. The study has some practical and pedagogical implications. On the one hand, it contributes some meaningful insights for language planners and policy-makers; on the other hand, the study sheds important light on the need to include the workplace dimension during language in education and language planning conversations. This study is also important because it addresses the issue of how code-switching might effectively be exploited as a communicative and pedagogical resource in instruction.
Effectiveness of Castration with Burdizzo, Calcium Chloride and Olive Oil in ‎Sahel Bucks

We evaluated the efficacy of castration with bilateral intratesticular injections of Calcium Chloride Dihydrate (CaCl2) in ethanol, Olive Oil as well as Burdizzo technique in twenty Sahel bucks. The bucks were randomly distributed into four groups as A, B, C and D. Group A served as the control and were given bilateral intratesticular injection of 1.0 ml of normal saline. Bucks in group B were castrated with Burdizzo, while group C and D were given bilateral intra testicular injection of 1.0 ml of CaCl2 and Olive oil, respectively. The sonograms and semen profiles of the bucks were evaluated.The diameters of the testicles and spermatic cords and the semen parameters were measured in real time after castration at days 1, 7, 14, 21, 28 and 60. The diameters in the Burdizzo, CaCl2‎and Olive oil castrated bucks ‎significantly increased (P < 0.05) on days 7 and was decreased at ‎day 60. ‎ Semen motility was absent in the bucks castrated with Cacl2 after day 14. The ‎concentration of spermatozoa also decreased significantly on day 7 in all the Burdizzo, CaCl2‎and ‎Olive oil castrated goats. Sonogram of testes castrated with Cacl2 showed discreet focal ‎hyperechoic, surrounded by ‎hypoechoic areas ‎within the parenchyma due to the CaCl2 deposition. The testes of bucks castrated with olive oil were ‎characterized by a central hypoechoic area ‎surrounded by clearly distinguishable hyperechoic ‎areas within the parenchyma. It was concluded that intratesticular injection with Burdizzo, CaCl2and olive oil resulted in successful castration but CaCl2 injection resulted in earlier azoospermia.
Evaluation of Dynamic Characteristics for a Submerged Body with Large Angle of Attack Motion via CFD Analysis

: A submerged body with varied control inputs can execute large drift angles and large angles of attack, as well as basic control such as straight movement and turning. The objective of this study is to analyze the dynamic characteristics of a submerged body comprising six thrusters and six control planes, which is capable of a large drift angle and angle of attack motion. Virtual captive model tests via were analyzed via computational fluid dynamics (CFD) to determine the dynamic characteristics of the submerged body. A test matrix of virtual captive model tests specialized for large-angle motion was established. Based on this test matrix, virtual captive model tests were performed with a drift angle and angle of attack of approximately 30° and 90°, respectively. The characteristics of the hydrodynamic force acting on the horizontal and vertical surfaces of the submerged body were analyzed under the large-angle motion condition, and a model representing this hydrodynamic force was established. In addition, maneuvering simulation was performed to evaluate the standard maneuverability and dynamic characteristics of large-angle motion. Considering the shape characteristics of the submerged body, we attempt to verify the feasibility of the analysis results by analyzing the characteristics of the hydrodynamic force when the large-angle motion occurred.
PATTERN OF DYSLIPIDEMIA IN PATIENTS WITH CRF

Objectives: (1)To find the pattern of dyslipidemias in patients with CRF. (2.)To compare the results with international studies. Design: Prospective observational study. Setting: In Medical UnitI, II, III and Nephrology ward of Allied Hospital Faisalabad. Period: (06 Months) From: Nov 2004 to April 2005. AlliedHospital is a teaching hospital attached with Punjab Medical College Faisalabad having 1100 beds. Chronic renalfailure, a very common disease, is accompanied by many complications. One of such complications is abnormality oflipids. The lipids are disturbed in a characteristic manner. This disturbed lipid pattern predisposes the patients toatherosclerotic complications and increased mortality due to cardiovascular and cerebrovascular accidents. Presentstudy was conducted to determine the pattern of dyslipidemias in patients of CRF.50 patients diagnosed to have CRFwere subjected to fasting lipid profile, irrespective of cause and sex. Maximum patients had elevated triglyceride levels(46%). A considerable percentage (16%) had decreased HDL levels and a small percentage had elevated LDL (4%). Total lipids were found to be elevated in 04 patients (8%). All the patients with elevated total lipid were suffering fromdiabetes mellitus. Total cholesterol was elevated in 08 patients (16%). This disturbed lipid pattern has role inatherosclerosis. The patients of CRF who are already having disturbed endothelial function are more prone to it.