Miracle-dz/UniFAR-FTUs huggingface dataset:
Marketing mix modeling for pharmaceutical companies on the basis of data science technologies

The article contains the results of Data Science technologies application (including machine learning and regression analysis) to modelling the results of marketing activities of key brand of one of the Ukrainian pharmaceutical companies on the basis of historical data for the period from 2015 to 2019 in weekly detail. The main goal of research is to estimate the influence of key elements of the marketing mix (penetration of pharmacy chains, price policy vs main competitors, advertising activity of the brand and its competitors in all communication channels (television, Digital, radio, outdoor advertising, press)) on company’s sales, volume market share and value market share in relevant segment of drugs. Based on the results obtained, the article explains in detail the impact of penetration, price policy and media activity on the competitiveness of the enterprise and its position in the market. The influence of the price policy and penetration directly on sales (market share), as well as on other factors (including the effectiveness of the brand's advertising activity on television) is estimated and taken into account for development the effective marketing strategy. Based on the research, the article contains main recommendations for optimizing the marketing strategy to maximize the company's sales and increasing market share in monetary or physical terms. Data Science technologies become a tool for sales management, because it creates the ability to quantify the impact of each factor on sales, determine their optimal combination for achievement of business goals and strengthening the company's position in the market, effective marketing budgets distribution and scenario forecasting. Continuous model support allows to increase the return on each factor, improve return on investment and ensure the achievement of business goals in the most efficient way. Data Science forms the basis for finding effective marketing solutions and forming an effective business development strategy.
Reactive Hyperemia-Triggered Wrist Pulse Analysis for Early Monitoring of Young Men with High Atherosclerotic Risk

The high prevalence of cardiovascular disease in young adults has raised significant concern regarding the early identification of risk factors to allow for timely intervention. This study aimed to identify young males at risk of atherosclerosis using a noninvasive instrument and an initial application percussion entropy analysis of the wrist pressure pulse (WPP). In total, 49 young males aged 18 to 28, without any known history of vascular disease, were recruited. Blood samples were obtained whereby a TC/HDL cutoff value of 4 was used to divide the young men into low-risk (Group 1, TC/HDL < 4, N = 32) and high-risk (Group 2, TC/HDL ≥ 4, N = 17) groups regarding atherosclerosis. The reactive hyperemia-triggered WPPs were measured using a modified air-pressure-sensing system (MAPSS). The dilation index (DI) of the endothelial function and percussion entropy index (PEI) of the heart rate variability (HRV) assessments, calculated using pragmatic signal-processing techniques, were compared between the two groups. The nonparametric Mann–Whitney U test showed that the DI and PEI of the two groups showed statistical differences (both p < 0.05). Not only could the MAPSS assess endothelial function and HRV in young males, but the results also showed that waist circumference and PEI may serve as indicators for the early identification of young males at risk of atherosclerosis.
DETERMINANTS OF THE ADOPTION OF INNOVATIVE FINTECH SERVICES BY MILLENNIALS

FinTech Adoption Index, expressed as a percentage of the digitally active population, for 27 countries of the world in 2019 reached the level of 64%. Millennials are the generation which, compared to others, is characterized by the highest level of FinTech adoptions. In Poland, in 2019, about 75% of the Millennials used the services of FinTech. This paper aims to analyse and evaluate the selected determinants of using the innovative FinTech services by Millennials in Poland. To investigate how users adopt FinTech services, we have applied our own set of determinants – selected from an extensive literature review – covering both demographic, economic and behavioural characteristics. This approach allowed for an in-depth analysis of the examined issue. The essential empirical data were obtained based on the research using the CAWI method in December 2019 on a representative sample of Poles aged 25–40 at that time. Ultimately, 1,236 correctly completed questionnaires were used for the research. To analyse and evaluate the impact of selected determinants of FinTech adoption, a logistic regression model was used. The results obtained can thus be extremely important for managers of financial institutions. They provide information that can be used for activities aimed at maintaining FinTech’s customer base and allow to adjust the offer to the expectations of this group. Millennials most open to innovative FinTech services in Poland are young men with high and very high net income and not driven by low costs of financial services. They appreciate technological novelties, including the possibility of using a smartwatch, and when deciding on the choice of a financial institution, they do not care about the direct opinions of their relatives and friends, but take into account the opinions in social media.
Evaluation of the New Beckmann Coulter Analyzer DxH 900 Compared to Sysmex XN20: Analytical Performance and Flagging Efficiency

Efficiency and accuracy in automated hematology analyzers are very important for clinical laboratories. The purpose was to evaluate the flags and results reported by the newest Beckman Coulter analyzer DxH 900 compared to the Sysmex XN20 system. Samples were analyzed on the XN20 (Sysmex, Kobe, Japan) and on the Beckman Coulter DxH 900 (Beckman Coulter, Miami, Florida, USA). Slide reviews were performed microscopically. Morphologic criteria were used to identify abnormal cells as recommended by International Consensus Group for Hematology (ICSH): blasts, immature granulocytes (IG%), abnormal lymphocytes (ALs) and plasma cells. Results: there was a strong correlation between the analyzers in almost all clinical parameters tested. Both DxH 900 and XN20 showed an excellent degree of association for the leukocyte differential compared to the reference method (manual microscopy). When it comes to IG%, XN20 showed a positive bias for higher results. Related to platelets, there are no differences between the two methods for PLT count. For mean platelet volume (MPV), DxH 900 provided 100% results of the samples analyzed while XN20 while in the XN20 analyzer, 16% of the results were missing. From our results we came to the conclusion that both analyzers, DxH 900 and XN20 were clinically accurate and efficient. Abnormal Lymphocyte detection highlighted the differences between the two technologies as only minimal agreement was obtained. DxH 900 demonstrated higher sensitivity in detecting IG with good correlation with microscopic review. The DxH 900 for platelet clumps identification provides an excellent flag (PLT Clumps) with the highest sensitivity observed in our evaluation.
Compressive Sensing Technique for Mitigating Nonlinear Memory Effects in Radar Receivers

Receiver nonlinearities pose a serious risk to the functionality of modern radars as they can compromise the sensor’s immunity to interfering signals. With the radio frequency (RF) spectrum becoming increasingly crowded, it is now more important than ever that the sensor can maintain system performance when exposed to mutual interference. In this article, we present a nonlinear compressive sensing (NCS) solution, which, unlike the standard nonlinear equalization (NLEQ) techniques, is designed around the forward nonlinearity rather than the inverse. Importantly, in this article, the NCS theory is extended to include nonlinear memory. Furthermore, a radar-specific formalization is derived, which allows the nonlinear optimization to exploit the unique properties of pulsed-Doppler radar processing. As a result, the NCS solution can successfully restore system sensitivity back to the linear case when in-band interference drives the radar receiver into its nonlinear regime. Additionally, it is shown that the technique can consistently mitigate complex nonlinear memory effects generated in the RF receiver. This is a significant result as it proves that forward modeling techniques are a viable alternative to NLEQ. This is of particular importance to radar systems as they provide a far more explicit formalization to mitigate nonlinear memory effects.
Barriers versus Benefits of Sustainable Practices: An Application to the Wine-Tourism Sector

ABSTRACT This study aims to identify the barriers to the implementation of sustainable practices and the benefits achieved by wine-tourism companies implementing those practices. To do so, quantitative research was carried out, by applying a questionnaire to 103 companies operating in the wine-tourism sector in Portugal. The results reveal the barriers affecting the implementation of sustainable practices and that the implementation of sustainable practices is positively associated with gaining multiple benefits. Despite the barriers associated with elaborating sustainability policies and their subsequent implementation, wine-tourism companies make efforts to adopt various practices with a view to sustainable development.
Environmental perceptions of global business travel by Swiss companies in the Zurich airport region

Background: This article presents findings from research conducted before the coronavirus disease 2019 (COVID-19) pandemic on companies located in the Zurich airport region of Switzerland, regarding the needs for global business travel and its impacts. Methods: The study involved a mixed methods approach. Five hypotheses were tested using inferential statistics on data obtained from pre-tested closed questions in a web-based survey. Deeper context was explored through an interview-based case-study conducted at a Swiss pharma company. Results: Supporting alternative hypothesis 3 (Ha(3)), a significant positive relationship was found between travel frequency and business growth, F(1, 100) = 11.31, p = 0.0011. Supporting Ha(4), corporate culture had a significant positive relationship with business travel frequency (F(1, 100) = 15.50, p = 0.0002) and average trip length (F(1, 100) = 6.39, p = 0.01). And thirdly supporting Ha(5), corporate social responsibility had a significant relationship with global business travel (91%). Ho(2) and Ho(3) were accepted. The case study found that smart corporate travel policies and regulations should be instantiated to enhance our environment, which would also benefit employee wellbeing. Travel can be reduced significantly despite being demonstrated that physical co-presence is important for building trust. The case study suggests tools to support the monitoring and management of global business travel by organizations. Conclusions: COVID-19 has impacted travel for business significantly, and future research will be necessary to assess its impact. The article explores the ongoing research in this area, and several relevant implications are proposed for future leaders. The case study found willingness to pay both corporate and individual green taxes, and a deficiency in corporate communication around the environment. Business travel is needed to build trust; however, it can be reduced.
Does State Repression Spark Protests? Evidence from Secret Police Surveillance in Communist Poland

Does physical surveillance hinder or foster antiregime resistance? A common view holds that surveillance prevents resistance by providing regimes with high-quality intelligence on dissident networks and by instilling fear in citizens. We contrast this view using formerly classified data from Communist Poland. We find that communities exposed to secret police officers were more likely to organize protests but also engaged in less sabotage. To ensure that the relationship is causal, we use an instrumental variable strategy, which exploits the exogenous assignment of Catholic “spy priests” to local communities. To trace the underlying mechanisms, we draw on qualitative interviews and archival sources. We document that Poland’s comprehensive use of surveillance created widespread anger as well as an incentive for citizens to reveal their true loyalties, thus facilitating antiregime collective action. Once on the streets, protesters refrained from sabotage to signal their political motivation to bystanders and authorities alike.
The Effect of Hexagon Fraud on the Potential Fraud Financial Statements with the Audit Committee as a Moderating Variable

This study aims to obtain empirical evidence of the influence of the six elements of fraud hexagon theory on potential financial statement fraud by involving the audit committee which acts as a moderating variable in the financial statements of state- owned companies listed on the Indonesia Stock Exchange in 2016-2020. Potential financial statement fraud is measured using the f-score model. The research sample was obtained by the purposive sampling technique. Data analysis methods and techniques include descriptive statistics, evaluation of the SEM-PLS model, and hypothesis testing. The results show that financial pressure has a positive effect on potential financial statement fraud, effective monitoring has a negative effect on potential financial statement fraud, while related party transactions, CEO education, CEO narcissism, and political connection do not affect potential financial statement fraud. The role of the audit committee as a moderating variable is only able to weaken the relationship between financial pressure and potential financial statement fraud.
EU measures to combat terrorist financing since 9/11: efficient, but not very effective

ABSTRACT Efforts to disrupt, deter and dismantle terrorist financing networks have become the key elements of the EU's post-9/11 counterterrorism policy. This reflects the prevailing wisdom which suggests that successfully executed counterterrorist financing (CTF) measures mitigate the first-mover advantage terrorists otherwise hold. Using EU’s own goals from its action plans and counterterrorism strategies as the baseline criteria, this article examines how successful the EU has been in implementing the relevant aspects of various UN Security Council resolutions, the special recommendations of the Financial Action Task Force, and its own CTF measures since 9/11. Reflecting the constant evolution of sources and methods of terrorist financing, the importance of cooperation with private financial institutions, and using publicly available data, the article also examines the impact of the EU CTF measures on terrorist financing in and beyond Europe.
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 values of mothers and their calves across southern right whale nursery grounds: The effects of nutritional stress?

School of Biology and Sea Mammal Research Unit, University of St Andrews, Scotland, UK Ecological Marine Services Pty. Ltd, Bundaberg, Queensland, Australia NTNU University Museum, Norwegian University of Science and Technology, Trondheim, Norway Grupo de Estudos de Mamíferos Aquáticos do Rio Grande do Sul, Torres, RS, Brazil Universidade Estadual do Rio Grande do Sul, Os orio, RS, Brazil School of Biological Sciences, University of Utah, Salt Lake City, Utah Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Laboratorio de Ecología Evolutiva Humana, Facultad de Ciencias Sociales, UNCPBA, Buenos Aires Province, Argentina
Hepatic Arterial Infusion Chemotherapy with Cisplatin versus Sorafenib for Intrahepatic Advanced Hepatocellular Carcinoma: A Propensity Score-Matched Analysis

Simple Summary Thus far, clinical studies have shown that immunotherapy (atezolizumab-bevacizumab) has shown better and favorable overall survival than sorafenib for advanced hepatocellular carcinoma (HCC). However, the treatment outcomes of hepatic arterial infusion chemotherapy (HAIC) with cisplatin compared with sorafenib for intrahepatic advanced HCC remain unclear. We therefore aimed to determine the prognostic factors for HAIC with cisplatin. Our results showed that HAIC with cisplatin could significantly prolong the overall survival for intrahepatic advanced HCC and had a longer prognostic effect than sorafenib. Therefore, our results suggest that HAIC should be used in intrahepatic advanced HCC. Abstract Given that the outcome of hepatic arterial infusion chemotherapy (HAIC) with cisplatin for intrahepatic advanced hepatocellular carcinoma (HCC) is unclear, we aimed to compare prognostic factors for overall survival (OS) following HAIC with cisplatin versus sorafenib for intrahepatic advanced HCC using propensity score-matched analysis. We enrolled 331 patients with intrahepatic advanced HCC who received HAIC with cisplatin (n = 88) or sorafenib (n = 243) between June 2006 and March 2020. No significant difference was observed in OS between HAIC with cisplatin and sorafenib cohorts (median survival time [MST]: 14.0 vs. 12.3 months; p = 0.0721). To reduce confounding effects, 166 patients were selected using propensity score-matched analysis (n = 83 for each treatment). HAIC with cisplatin significantly prolonged OS compared with sorafenib (MST: 15.6 vs. 11.0 months; p = 0.0157). Following stratification according to the Child-Pugh classification, for patients with class A (MST: 24.0 vs. 15.0 months; p = 0.0145), HAIC with cisplatin rather than sorafenib significantly prolonged OS. Our findings suggest that HAIC with cisplatin demonstrates longer prognostic effects than sorafenib in intrahepatic advanced HCC.
THE EFFECTS OF TWO ANTIPSYCHOTIC DRUGS AND PROLACTIN ON TOXOPLASMA GONDII TACHYZOITES IN VIVO

Chronic toxoplasmosis is associated with psychotic disorders. Multiple in vitro studies showed that many antipsychotic medications have anti-Toxoplasma activity. Meanwhile, there is very limited data regarding the inhibitory effect of them on Toxoplasma in vivo. This study evaluated the activity of Chlorpromazine, Clozapine, and prolactin (a pituitary gland hormone) on toxoplasmosis infected rats. Clean laboratory breed rats were chronically infected with non-virulent T. gondii strain and classified into 8 groups: negative, positive control groups, chlorpromazine, clozapine, and metoclopramide drug control groups, and 3 infected treated groups. Rat were screened with ELISA test to evaluate level of dopamine, interferon gamma, and prolactin. All drugs were effective against T. gondii in infected rats. Dopamine level and INFwere significantly decreased in chlorpromazine infected treated rats. There was significant decrease of dopamine level and increase of prolactin level in clozapine infected treated rats. In metoclopramide infected treated rats prolactin level significantly increased, but INFlevel significantly decreased.
Perceived Abusive Leadership, Narcissistic Personality, and Employee's Political Behaviors: A Moderated-Mediation Model

Limited research has explored the potential explanatory mechanisms for the link between abusive leadership and non-negative employee-based behaviors in the effectiveness of organizational management. Based on affective response theory to construct a theoretical model, this study enhances the mapping of how employee-perceived abusive leadership triggers employee affective responses and influences their political behaviors to facilitate task-related goals. It also investigates how the moderating effects of employee-perceived leader's narcissistic personality interact with the variables of the main effects. This study was implemented in Taiwan's financial and insurance institutions. Using a sampling framework via a market survey agency, participants completed three online surveys within a 3-week period. 350 employed participants registered for the study. Based on the findings, we suggest that managers in a hierarchical organization may be able to intentionally vary their leadership style to arouse employees' negative emotions without hindering, and perhaps even improving, employees' motivation to achieve their task aims. When leaders demonstrate their self-confidence in the workplace, employees perceive less anxiety at work and less need to adopt workplace political behaviors to solve work troubles. This research suggests managers should recognize employee-perceived abusive leadership as an influential factor that contributes to illuminating the processes underlying workplace perception-to-behavior and leader–member interactive links, as well as the boundary conditions of mediating and moderating these processes.
Investigation of Faculty Members’ Emotional Intelligence

The main aim of the present study is to investigate the emotional intelligence of faculty members based on their career stage and gender. In the study, a mixed method was employed to determine the emotional intelligence of faculty members and to reach generalizable findings. The convenience sampling method was used in the quantitative study, while the quota sampling method was used in the qualitative section. The quantitative section sample included faculty members in various stages in their careers. In the qualitative dimension, the sample included faculty members who participated in the quantitative application. The quantitative study findings demonstrated that there were significant differences between the emotional intelligence competencies of female and male faculty members in the workplace based on the empathy and self-awareness dimensions. The qualitative study findings revealed that there were differences between the emotional intelligence dimensions, especially based on the career stage and gender. Recommendations are presented based on the study findings.
Effect of Production System and Age on Egg Quality Parameters: A Case of Niğde Province Çamardı District, Turkey

This study compared egg quality parameters in layers under free-range system with prefabricated pens and backyard while emphasizing hen age. A total of 300 eggs collected from prefabricated pens and backyard farming families in the Çamardı District of Niğde Province were used as study materials. The assessed external and internal egg quality characteristics included egg weight, shape index, shell thickness, shell breaking strength, albumen index, Haugh unit, yolk index, and yolk colour. The effect of production system on albumen index, Haugh unit, and yolk colour score was found statistically significant. There was a significant effect of age on shape index, shell thickness, shell breaking strength, albumen index, Haugh Unit, yolk index, and yolk colour score. The effect of interaction between age and production system was statistically significant for shape index, shell thickness, yolk index, Haugh Unit, and yolk colour score. It was determined that the egg`s meat and blood spots percentages from the free-range and backyard systems were 10.6% and 15.3%, respectively. It was concluded that while eggs produced from free-range system are superior in terms of egg weight, shape index, and Haugh unit those obtained from backyard hens are higher in eggshell thickness, eggshell breaking strength, and egg yolk colour.