Miracle-dz/UniFAR-FTUs huggingface dataset:
A Shortcut Approach for Large-scale Mixed Model Associations with Binary Traits

Generalized linear mixed models exhibit computationally intensive and biasness in mapping quantitative trait nucleotides for binary diseases. In genomic logit regression, we consider genomic breeding values estimated in advance as a known predictor, and then correct the deflated association test statistics by using genomic control, thereby successfully extending GRAMMAR-Lambda to analyze binary diseases in a complex structured population. Because there is no need to estimate genomic heritability and genomic breeding values can be estimated by a small number of sampling markers, the generalized mixed-model association analysis has been extremely simplified to handle large-scale data. With almost perfect genomic control, joint analysis for the candidate quantitative trait nucleotides chosen by multiple testing offered a significant improvement in statistical power.
In utero accumulated steroids predict neonate anti‐predator response in a wild mammal

This is an open access article under the terms of the Creative Commons AttributionNonCommercialNoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is noncommercial and no modifications or adaptations are made. © 2021 The Authors. Functional Ecology published by John Wiley & Sons Ltd on behalf of British Ecological Society 1Laboratory of Wildlife Ecology and Behaviour, School of Biology and Environmental Science, University College Dublin, Dublin, Ireland 2School of Biological Sciences, Queen's University Belfast, Belfast, UK 3The Mina and Everard Goodman Faculty of Life Sciences, BarIlan University, RamatGan, Israel
Sea Surface Temperature Anomalies in the Western Indian Ocean as a Trigger for Atlantic Niño Events

Pacific El Niño and Atlantic Niño events represent prominent interannual climate fluctuations in tropical regions. Both of them have considerable impacts on the climate system and human livelihoods. The interaction between the Pacific El Niño and Atlantic Niño has received wide attention. Here, we use observations and numerical model experiments to show a new trigger from the western Indian Ocean (WIO) that can serve as a predictor for Atlantic Niño events. The warm sea surface temperature (SST) anomalies in the WIO alter the Walker circulation in the boreal winter, weaken the surface trade winds over the tropical Atlantic and favor an Atlantic Niño in the subsequent summer. These inter‐basin processes also affect the interaction between the Pacific El Niño and Atlantic Niño. The results imply that a better simulation of the WIO SST and its teleconnection may help to forecast Atlantic Niño events.
Foreign Direct Investment Spillovers and Economic Growth: Evidence from Asian Emerging Countries

Research on FDI in promoting economic growth has been the focus of recent decades, especially in developing countries. Foreign direct investment can be one of the main objectives in increasing economic growth. FDI is assumed to indirectly contribute to economic growth through a spillover effect on the absorption capacity of a country by increasing the stock of human capital and the quality of institutions. This study aims to analyze the spillover effect of FDI on economic growth in Asian emerging markets. The data were analyzed using dynamic panel regression (GMM) during 2008-2017 period with STATA 14 software.The results in this study strongly indicate that the spillovers of FDI is proven to be able to drive economic growth through human capital and institutions in Asian emerging markets.
Examining the impact of uniform manipulations on perceptions of police officers among Canadian university students

ABSTRACT It is important to understand how uniforms influence public perceptions of the police. The current study utilized a randomized design in which undergraduate students at a Canadian university were exposed to a series of photographs of officers wearing different uniform configurations (i.e., special duty vs. traditional uniform, dark vs. light shirt, dishevelled vs. tidy uniform, and uniform trousers with and without a stripe). Participants rated each officer on numerous scales including: (1) the officer’s personal qualities (e.g., helpfulness), (2) abilities or behaviors that the officer is likely to display (e.g., excessive force), and (3) the behavioral intentions of the participant toward the observed officer (e.g., willing to confide sensitive information to them). When controlling for general perceptions of police legitimacy, results suggest that, compared to the control conditions (i.e., normal operational uniform), introducing the uniform manipulations significantly influenced ratings on items related to community relations, professionalism, and officer safety. The current study speaks to the complicated relationship between the police appearing approachable and professional to the public, while also considering possible officer safety concerns associated with their uniform.
Changes in spring vegetation greenness over Siberia associated with weather disturbances during 1982–2015

As the global climate warms rapidly, terrestrial vegetation experiences significant changes. The impact of high‐frequency variability, especially for variations related to weather disturbances (i.e., day‐to‐day weather fluctuations), however, is less studied and remains poorly understood. In the present study, we quantitatively investigated the linkages between the normalized difference vegetation index (NDVI) and weather disturbances in spring (April and May) over Siberia for the period 1982–2015. Identified by empirical orthogonal function analysis, the inherent large‐scale spatial structure of weather disturbances shows synchronous variations over Siberia. It was found that weather disturbances are significantly related to the synchronous NDVI at a large spatial scale. The regional mean (48–67°N and 50–105°E) time series of the NDVI and weather variance, a measure of weather disturbance, is correlated at −0.32 (significant at the 0.05 level), suggesting that in springs with larger weather fluctuations, the concurrent NDVI tends to clearly decrease. Changes of frost events in association with weather disturbances are investigated to help understand the vegetation greenness response. We identified springs with the largest and smallest weather variances. Then, their differences were utilized to estimate the possible maximum changes for extremely cold temperatures. The results show that corresponding to the largest variance increase, for Siberia as a whole, the number of frost days has increased by 0.9 days (5%) and the accumulated adverse temperature has undergone a substantial increase of 18.9°C·day (15%). These results suggest that when there are active weather disturbances, the simultaneous increase in extremely cold temperatures plays a dominant role in adversely impacting vegetation activity. Our study demonstrates that, in addition to the increased mean temperature, the long‐term decrease in weather disturbances over Siberia, as observed in recent decades, should also contribute significantly to vegetation greening. This finding promotes a further understanding of the impacts of climate change on regional vegetation activity.
Physiological effects of a sublethal concentration of inhaled phenol on the rat1

After 15 days' exposure to phenol at 100 mg/m8 in an inhalation chamber at 27 °C tests with the "tilting- plane" method demonstrated that this sublethal concentration had had a significant effect on the central nervous system of rats. No significant effects on haemoglobin or haematocrit values could be demonstrated, and plasma sodium, calcium and chloride values were unaffected. On the other hand, plasma potassium and magnesium values were significantly elevated. The activities of the plasma enzymes LDH, GOT, GPT, and GLDH were also significantly elevated. At the concentration used phenol did not have any effect on the weight of the test animals. The total amount of free phenols in plasma remained unaltered.
An Adlerian-Based Empowering Intervention Program With Burned-Out Teachers

We examined the effects of an intervention program based on Adlerian psychology on the burned-out teachers. By administering the Maslach Burnout Inventory (MBI) and the Achievement Motivation Test (AMT), we identified 60 teachers with burnout symptoms. The experimental group attended eight sessions of the intervention program with different cognitive restructuring techniques and motivational themes to facilitate psychological empowerment. The findings demonstrated the positive effects of the program on alleviating burnout with cognitive and behavioral changes in the participants’ personal and professional lives. The durability of these improvements was moderate at a 6-month follow-up after the intervention.
Assessing the Risk of Legionella Infection through Showering with Untreated Rain Cistern Water in a Tropical Environment

In September 2017, two category-5 hurricanes Irma and Maria swept through the Caribbean Sea in what is now known as the region’s most active hurricane season on record, leaving disastrous effects on infrastructure and people’s lives. In the U.S. Virgin Islands, rain cisterns are commonly used for harvesting roof-top rainwater for household water needs. High prevalence of Legionella spp. was found in the cistern water after the hurricanes. This study carried out a quantitative microbial risk assessment to estimate the health risks associated with Legionella through inhalation of aerosols from showering using water from cisterns after the hurricanes. Legionella concentrations were modeled based on the Legionella detected in post-hurricane water samples and reported total viable heterotrophic bacterial counts in cistern water. The inhalation dose was modeled using a Monte Carlo simulation of shower water aerosol concentrations according to shower water temperature, shower duration, inhalation rates, and shower flow rates. The risk of infection was calculated based on a previously established dose–response model from Legionella infection of guinea pigs. The results indicated median daily risk of 2.5 × 10−6 to 2.5 × 10−4 depending on shower temperature, and median annual risk of 9.1 × 10−4 to 1.4 × 10−2. Results were discussed and compared with household survey results for a better understanding of local perceived risk versus objective risk surrounding local water supplies.
Public Service Motivation and Individual Job Performance

When pressure on human resource departments to make government more efficient is increasing, it is of great relevance to understand employees’ motivation and the fit of an employee with their job, as both contribute strongly to service performance. Therefore, this chapter discusses the role of public employees’ motivation and its relationship to individual performance. More specifically, this relationship is examined by focusing on public service motivation (PSM), a stream of research developed during the last three decades stressing the service orientation of public employees’ identity. Theoretically, how the relationship between PSM and individual performance is dependent on institutions is discussed, and an overview of the existing empirical evidence concerning this relationship is provided. The literature review discusses a variety of aspects such as direct vs. indirect effects, type of performance used, how performance is measured, and effect sizes. Finally, several avenues for future research are proposed, including methodological strategies.
An Overview of Drugs Used in COVID-19: A Pharmacotherapeutic Approach

Coronavirus originated pandemic disease also called Corona Virus Disease 2019 (COVID-19) is spread all over the world causing severe acute respiratory syndrome (SARS) called SARS-CoV-2 poses a difficult challenge to scientists, researchers, and practitioners to discover effective drugs for prevention and treatment. By using a huge amount of clinical data obtained from many SARS-CoV2 infected people, clinicians are trying to gather accurate evidence for effective treatment and also developing a suitable vaccine system for the prevention of spread of infection for many more people. With no proven therapies which can treat and prevent SARS-CoV-2 is developed until now, there is an opportunity for new researchers in virology to make such an attempt at this crucial time. In this regard, currently, two strategies are active. The first kind of strategy is on developing completely new molecules to prevent and treat this disease, or the second strategy is on testing the effectiveness of already available antivirals and antimalarials for possible potential recovery and prevention. This is done by testing several antivirals (Remdesivir, Favipiravir, etc) and antimalarials (Chloroquine, Hydroxychloroquine, etc) for their potential therapies. Studies show that the most promising therapy is the use of antiviral Remdesivir. Remdesivir has shown the potential ability to exhibit vitro activity to control COVID-19. The drug is currently being tested by ongoing randomized trials. Until a widely accepted drug reaches the global market, different antiviral treatment strategies are used under urgent investigation. In this article, we review the latest research developments related to the systematic treatments for COVID-19 reported from various research labs of different countries. The article also provides a summary of various clinical research experience, intermediate results, and treatment guidance to combat the novel coronavirus epidemic based on pharmacotherapeutic analysis, along with insights to the attempts on vaccine development across the world in order to curb the COVID pandemic.
Elemental accumulation in the surficial sediment of Kesikköprü, Çubuk II and Asartepe Dam Lakes (Ankara) and potential sediment toxicity

ABSTRACT In this study, Çubuk 2, Kesikköprü and Asartepe Dam Lake, were investigated. A total of 60 sediment samples were collected and the concentrations of 10 elements (Cu, Pb, Zn, Ni, Mn, Fe, Co, Cr, Al, As) were determined. The obtained findings were compared to the limit values for the sediment quality guidelines (SQGs) and were investigated using sediment assessment methods. The results indicate that the values for SQGs revealed that the concentrations of Ni and As should be emphasised. Toxic unit (TU) values showed that As and Ni together constitute 69.95–80.09% of the total toxic effect alone for all lakes. In addition, the Contamination factor (Cf) and Enrichment factor (EF) detected the concentration of As for Kesikköprü Dam Lake as being at a medium and higher accumulation levels, although the Geoaccumulation index (Igeo) detected that As leads to contamination below the medium level. When the total element accumulation was evaluated, no risk was detected for the lakes. Cluster analysis (CA) revealed quite different elemental profiles for 3 lakes. The strongest correlation between the elements was observed for Cu-Ni (r = 0.942) in Çubuk 2, whereas Çubuk 2 was the lake with the highest seasonal elemental variation among the lakes investigated.
Remarks of Eimeria labbeana infection in Egyptian pigeons

This work was conducted to investigate the course of Eimeria labbeana infection in Egyptian pigeons (Columbia Livia). Thirty squabs were experimentally infected orally with 2.5 x104 sporulated Eimeria labbeana oocysts. Daily scarification of three squabs was done from day one post-infection (PI) until day 8 PI for following of the endogenous stages in tissue samples and 6 squabs were kept to follow the patent period and daily oocyst shedding. Paraffin-embedded intestinal samples were sectioned and stained for differentiation of parasitic stages. The infected squabs showed greenish watery diarrhea, weakness, rough feathers, and decrease food intake at day 5 PI. The pre-patent and patent periods were 6 and 14 days PI respectively. The oocyst shedding started at day 6 PI and reached the peak at day 8 PI. Histopathological examination revealed the presence of three schizont stages, macro-and micro-gametes, and oocysts in the duodenal and jejunal parts of the small intestine. In conclusion, it is the first study on Egypt on Eimeria labbeana in Egyptian pigeons and its biology is like recorded before.
Impact of Coordination, Psychological Safety, and Job Security on Employees’ Performance: The Moderating Role of Coercive Pressure

Based on institutional theory, the current study examines the relationship of coordination, job security, psychological safety, and coercive pressure with employees’ performance. Further, coercive pressure is treated as a boundary condition between coordination, job security, and psychological safety with employees’ performance. A survey method was used to collect data from 235 faculty members of higher education institutions (HEIs) in Pakistan. Study results show that there is a positive and significant relationship between job security and coordination with employees’ performance. The results also reveal that coercive pressure moderates job security, coordination, and psychological safety with employees’ performance. Implications for organizations and HEIs administration are discussed.
Characterisation and evaluation of antibacterial potential of guava extract loaded poly-3-hydroxybutyrate-co-3-hydroxyvalerate nanoparticles against multidrug-resistant bacteria

In this work, the antibacterial potential of different plant's leaves, i.e. Psidium guajava (guava), Raphanus sativus (radish), Solanum pseudocapsicum (winter cherry), Mentha royaleana (mint) and Calotropis procera (rubber tree) was evaluated against the multidrug-resistant (MDR) bacteria. Methicillin-resistant Staphylococcus aureus (MRSA), Vibrio cholerae O1 El Tor (VC O1 ET), V. cholerae Non-O1/Non-O139 (VC N-O1/N-O139), enteroaggregative Escherichia coli (EAEC) and enteropathogenic Escherichia coli (EPEC) were included among the MDR bacterial strains. The significantly high (P < 0.001) antibacterial activities were observed against the MDR bacteria in case of the methanol extract of the P. guajava (GUV) leaves. The characterisation studies of GUV extract were done by thin layer chromatography, wide angle X-diffraction and Fourier transform infrared techniques. The GUV extract was encapsulated in poly-3-hydroxybutyrate-co-3-hydroxyvalerate (PHBV) nanoparticles using the nanoprecipitation method. Blank PHBV nanoparticles demonstrated no antibacterial activity against the selected MDR strains. The GUV extract loaded PHBV nanoparticles produced significantly large (P < 0.001) zones of inhibition, i.e. MRSA (24 mm), EPEC (23 mm), EAEC (23 mm), VC O1 ET (21 mm) and VC N-O1/N-O139 (20 mm) against the MDR bacterial strains as compared with the GUV extract alone. The results have demonstrated a great potential of PHBV nanoparticles to become an efficient carrier for delivery of the potent bioactive molecules.
Marmora of the Traianeum of Italica (Santiponce, Seville, Spain): New data provided by archaeometric analysis

This article aims to identify a series of stone materials used in the ornamentation of the Traianeum of Italica (Santiponce, prov. Seville, Spain), the imperial cult shrine commissioned by Hadrian in honour of his adoptive father, Trajan, from a petrographic, mineralogical, and geochemical point of view. The study highlights the simultaneous use of local and, above all, foreign marbles. Local marbles from Almadén de la Plata (prov. Seville) and Hill of Mijas (prov. Malaga) were used particularly for wall coverings and pavements, whereas Luni‐Carrara marble stands out as the preferred ornamental foreign marble used in column shafts, bases, capitals, balustrade finishes, and so forth. In addition, cipollino marble was mainly used for the column shafts of the hecatostylon portico, but the analysis has not been able to specify its exact provenance, whether it is from Euboea or local, possibly the area of Almadén de la Plata. However, given that this was a construction promoted by the emperor, it might be possible that it would have come from Greece.
Beyond identity consciousness: human resource management practices and mental health conditions in sheltered workshops

Abstract This study examines how individuals with mental health conditions (MHCs) are supported and managed in sheltered workshops in France. Based on interviews with sheltered workshop professionals and observations in these organizations, this qualitative study identifies and describes human resource management (HRM) practices related to individuals with MHCs and how these practices come into being. Three types of practices were identified: identity-blind practices, which are common to all employees regardless of their disability types; identity-conscious practices, which are specifically adapted to individuals with MHCs; and individual-conscious practices, which go beyond a mental health diagnosis and are specifically adapted to the individual at a particular moment in time. Several drivers lead to these practices: organizational or individual awareness of the need for adaptation, the intention to adapt, the availability of organizational resources, and the organizations’ allowance for flexibility. By analyzing the specific needs of individuals with MHCs in the sheltered sector, the article extends the concepts of identity-blind and identity-conscious practices and outlines several types of HRM diversity practices.
Transcripts of Unfulfillment: A Study of Sexual Dysfunction and Dissatisfaction among Malay-Muslim Women in Malaysia

The prevalence of female sexual dysfunction (FSD), or in everyday notion, sexual dissatisfaction, among Malay women remains high, denoting that there are several influences shaping their experience of sex within marriage. This qualitative study identified the perceived effects of social factors in the development of sexual dysfunction among Malay women. Engaging a phenomenological framework, 26 in-depth face-to-face interviews were conducted among married women from Peninsular Malaysia, based on their self-reporting of FSD symptoms. All sessions were audio-recorded and the data were transcribed verbatim and managed in the ATLAS.ti software before being analysed. The three themes that emerged—‘sex is taboo and culturally unacceptable’, ‘self-ignorance about sex’, and ‘lack of husband’s role in mutual sexual enjoyment’—suggest some influence of Islamic teachings and cultural conduct, as in Adat, on sexuality in society. However, a lack of knowledge and nonadherence to positive values and teachings around sexual satisfaction between men and women, as espoused through the Islamic religion, have affected woman’s sexual functions and coupling relationship even more significantly. The results of this qualitative study show that a formal, culturally sensitive, and comprehensive sex education programme incorporating both medical and Islamic knowledge may work to effectively reduce FSD.