Miracle-dz/UniFAR-FTUs huggingface dataset:
Gravity field and solar component of the precession rate and nutation coefficients of Comet 67P/Churyumov–Gerasimenko

The aim of this study is first to determine the gravity field of the comet 67P Churyumov-Gerasimenko and second to derive the solar component of the precession rate and nutation coefficients of the spin axis of the comet nucleus, i.e. without the direct, usually larger, effect of outgassing. The gravity field, and related moments of inertia, are obtained from two polyhedra, that are provided by the OSIRIS and NAV-CAM experiments on Rosetta, and are based on the assumption of uniform density for the comet nucleus. We also calculate the forced precession rate as well as the nutation coefficients on the basis of Kinoshita's theory of rotation of the rigid Earth and adapted it to be able to indirectly include the effect of outgassing on the rotational parameters. The 2nd degree denormalized Stokes coefficients of comet 67P C-G turn out to be (bracketed numbers refer to second shape model) C20 = -6.74 [-7.93] * 10^-2, C22 = 2.60 [2.71] * 10^-2 consistent with normalized principal moments of inertia A/MR^2 = 0.13 [0.11], B/MR^2 = 0.23 [0.22], with polar moment c = C/MR^2 = 0.25, depending on the choice of the polyhedron model. The obliquity between the rotation axis and the mean orbit normal is 52 degree, and the precession rate only due to solar torques becomes 20-30 "/y. Oscillations in longitude caused by the gravitational pull of the Sun turn out to be of the order of 1', oscillations in obliquity can be estimated to be of the order of 0.5'.
CHARACTERISTICS OF SPIRAL ARMS IN LATE-TYPE GALAXIES

We have measured the positions of large numbers of H ii regions in four nearly face-on, late-type, spiral galaxies: NGC 628 (M74), NGC 1232, NGC 3184, and NGC 5194 (M51). Fitting log-periodic spiral models to segments of each arm yields local estimates of spiral pitch angle and arm width. While pitch angles vary considerably along individual arms, among arms within a galaxy, and among galaxies, we find no systematic trend with galactocentric distance. We estimate the widths of the arm segments from the scatter in the distances of the H ii regions from the spiral model. All major arms in these galaxies show spiral arm width increasing with distance from the galactic center, similar to the trend seen in the Milky Way. However, in the outermost parts of the galaxies, where massive star formation declines, some arms reverse this trend and narrow. We find that spiral arms often appear to be composed of segments of ∼5 kpc length, which join to form kinks and abrupt changes in pitch angle and arm width; these characteristics are consistent with properties seen in the large N-body simulations of D'Onghia et al. and others.
Effectiveness and cost-effectiveness of an intensive and abbreviated individualized smoking cessation program delivered by pharmacists: A pragmatic, mixed-method, randomized trial

Background: Tobacco use is the leading preventable cause of morbidity and mortality in Canada. Smoking cessation programs (SCPs) that are effective, cost-effective and widely available are needed to help smokers quit. Pharmacists are uniquely positioned to provide such services. This study compares the abstinence rates between 2 pharmacist-led SCPs and the cost-effectiveness between these and a comparator group. The study was conducted in St. John’s, Newfoundland and Labrador. Methods: This pragmatic, mixed-method trial randomized smokers to either an existing intensive SCP or a new abbreviated SCP designed for community pharmacies. The primary outcome was 6-month abstinence rates. Cost-effectiveness was determined using abstinence rates for the SCPs and a comparator group. Incremental costs per additional quit were calculated for the trial duration, and incremental costs per life-year gained were estimated over a lifetime. Results: Quit rates for the SCPs were 36% (intensive) and 22% (abbreviated) (p = 0.199). Incremental costs per life-year gained for the SCPs were $1576 (intensive) and $1836 (abbreviated). The incremental costs per additional quit, relative to the comparator group, for the SCPs were $1217 (intensive) and $1420 (abbreviated). Discussion: Both SCPs helped smokers quit, and quit rates exceeded those reported for a comparator group that included a general population of adult smokers (~7%). The incremental costs per additional quit for both SCPs compare favourably to those reported for other initiatives such as quit lines and hospital-based interventions. Conclusion: Pharmacist-led smoking cessation programs are effective and highly cost-effective. Widespread implementation, facilitated by remuneration, has potential to lower smoking prevalence and associated costs and harms.
Minor versus major mergers: the stellar mass growth of massive galaxies from z = 3 using number density selection techniques

We present a study on the stellar mass growth of the progenitors of local massive galaxies with a variety of number density selections with $n\le1\times10^{-4}\,\rm{Mpc^{-3}}$ (corresponding to $M_*=10^{11.24}\rm{M_{\odot}}$ at z=0.3) in the redshift range $0.3<z<3.0$. We select the progenitors of massive galaxies using a constant number density selection, and one which is adjusted to account for major mergers. We find that the progenitors of massive galaxies grow by a factor of four in total stellar mass over this redshift range. On average the stellar mass added via the processes of star formation, major and minor mergers account for $24\pm8\%$, $17\pm15\%$ and $34\pm14\%$, respectively, of the total galaxy stellar mass at $z=0.3$. Therefore $51\pm20\%$ of the total stellar mass in massive galaxies at $z=0.3$ is created externally to their z=3 progenitors. We explore the implication of these results on the cold gas accretion rate and size evolution of the progenitors of most massive galaxies over the same redshift range. We find an average gas accretion rate of $\sim66\pm32\,\rm{M_{\odot}yr^{-1}}$ over the redshift range of $1.5<z<3.0$. We find that the size evolution of a galaxy sample selected this way is on average lower than the findings of other investigations.
Adaptive polarimetric image representation for contrast optimization of a polarized beacon through fog

We present a contrast-maximizing optimal linear representation of polarimetric images obtained from a snapshot polarimetric camera for enhanced vision of a polarized light source in obscured weather conditions (fog, haze, cloud) over long distances (above 1 km). We quantitatively compare the gain in contrast obtained by different linear representations of the experimental polarimetric images taken during rapidly varying foggy conditions. It is shown that the adaptive image representation that depends on the correlation in background noise fluctuations in the two polarimetric images provides an optimal contrast enhancement over all weather conditions as opposed to a simple difference image which underperforms during low visibility conditions. Finally, we derive the analytic expression of the gain in contrast obtained with this optimal representation and show that the experimental results are in agreement with the assumed correlated Gaussian noise model.
K+A GALAXIES AS THE AFTERMATH OF GAS-RICH MERGERS: SIMULATING THE EVOLUTION OF GALAXIES AS SEEN BY SPECTROSCOPIC SURVEYS

Models of poststarburst (or “K+A”) galaxies are constructed by combining fully three-dimensional hydrodynamic simulations of galaxy mergers with radiative transfer calculations of dust attenuation. Spectral line catalogs are generated automatically from moderate-resolution optical spectra calculated as a function of merger progress in each of a large suite of simulations. The mass, gas fraction, orbital parameters, and mass ratio of the merging galaxies are varied systematically, showing that the lifetime and properties of the K+A phase are strong functions of the merger scenario. K+A durations are generally ≲0.1–0.3 Gyr, significantly shorter than the commonly assumed 1 Gyr, which is obtained only in rare cases, owing to a wide variation in star formation histories resulting from different orbital and progenitor configurations. Combined with empirical merger rates, the model lifetimes predict rapidly rising K+A fractions as a function of redshift that are consistent with results of large spectroscopic surveys, resolving tension between the observed K+A abundance and that predicted when one assumes the K+A duration is the lifetime of A stars (∼1 Gyr). These simulated spectra are spatially resolved on scales of about 1 kpc, and indicate that a centrally concentrated starburst causes the Balmer absorption strengths to increase toward the central few kiloparsecs of the remnant. The effects of dust attenuation, viewing angle, and aperture bias on our models are analyzed. In some cases, the K+A features are longer-lived and more pronounced when active galactic nucleus (AGN) feedback removes dust from the center, uncovering the young stars formed during the burst. In this picture, the K+A phase begins during or shortly after the bright starburst/AGN phase in violent mergers, and thus offers a unique opportunity to study the effects of quasar and star formation feedback on the gas reservoir and evolution of the remnant. Analytic fitting formulae are provided for the estimates of K+A incidence as a function of merger scenario.
Generalized perturbations in neutrino mixing

We derive expressions for the neutrino mixing parameters that result from complex perturbations on (1) the Majorana neutrino mass matrix (in the basis of charged lepton mass eigenstates) and on (2) the charged lepton mass matrix, for arbitrary initial (unperturbed) mixing matrices. In the first case, we find that the phases of the elements of the perturbation matrix, and the initial values of the Dirac and Majorana phases, strongly impact the leading-order corrections to the neutrino mixing parameters and phases. For experimentally compatible scenarios wherein the initial neutrino mass matrix has $\ensuremath{\mu}\ensuremath{-}\ensuremath{\tau}$ symmetry, we find that the Dirac phase can take any value under small perturbations. Similarly, in the second case, perturbations to the charged lepton mass matrix can generate large corrections to the mixing angles and phases of the Pontecorvo-Maki-Nakagawa-Sakata (PMNS) matrix. As an illustration of our generalized procedure, we apply it to a situation in which nonstandard scalar and nonstandard vector interactions simultaneously affect neutrino oscillations.
Evolution of Gene Arrangements in the Mitogenomes of Ensifera and Characterization of the Complete Mitogenome of Schizodactylus jimo

Gene arrangement (relative location of genes) is another evolutionary marker of the mitogenome that can provide extensive information on the evolutionary mechanism. To explore the evolution of gene arrangements in the mitogenome of diversified Ensifera, we sequenced the mitogenome of the unique dune cricket species found in China and used it for phylogenetic analysis, in combination with 84 known Ensiferan mitogenomes. The mitogenome of Schizodactylus jimo is a 16,428-bp circular molecule that contains 37 genes. We identified eight types of gene arrangement in the 85 ensiferan mitogenomes. The gene location changes (i.e., gene translocation and duplication) were in three gene blocks: I-Q-M-ND2, rrnl-rns-V, and ND3-A-R-N-S-E-F. From the phylogenetic tree, we found that Schizodactylus jimo and most other species share a typical and ancient gene arrangement type (Type I), while Grylloidea has two types (Types II and III), and the other five types are rare and scattered in the phylogenetic tree. We deduced that the tandem replication–random loss model is the evolutionary mechanism of gene arrangements in Ensifera. Selection pressure analysis revealed that purifying selection dominated the evolution of the ensiferan mitochondrial genome. This study suggests that most gene rearrangements in the ensiferan mitogenome are rare accidental events.
THE SLOPE OF THE BARYONIC TULLY–FISHER RELATION

We present the results of a baryonic Tully–Fisher relation (BTFR) study for a local sample of relatively isolated disk galaxies. We derive a BTFR with a slope near 3 measured over about 4 dex in baryon mass for our combined H i and bright spiral disk samples. This BTFR is significantly flatter and has less scatter than the TFR (stellar mass only) with its slope near 4 reported for other samples and studies. A BTFR slope near 3 is in better agreement with the expected slope from simple ΛCDM cosmological simulations that include both stellar and gas baryons. The scatter in the TFR/BTFR appears to depend on W20: galaxies that rotate slower have more scatter. The atomic gas-to-stars ratio shows a break near W20 = 250 km s−1 probably associated with a change in star formation efficiency. In contrast, the absence of such a break in the BTFR suggests that this relation was probably set at the main epoch of baryon dissipation rather than as a product of later galactic evolution.
Supplementation with long chain n-3 fatty acids during pregnancy, lactation, or infancy in relation to risk of asthma and atopic disease during childhood: a systematic review and meta-analysis of randomized controlled clinical trials

Objective To assess whether supplementation with long chain n-3 fatty acids during pregnancy, lactation, or infancy reduces the risk of developing asthma or atopic disease during childhood. Methods Searches were performed in MEDLINE, Embase, Cochrane Central Register of Controlled Trials, and Scopus up to 2021-09-20, for randomized controlled trials (RCTs) that investigated the effect of supplemental long chain n-3 fatty acids during pregnancy, lactation, or infancy for the prevention of childhood asthma or allergy. Article selection, data extraction, and risk of bias assessment (Cochrane’s Risk of Bias 2.0) were independently conducted by two assessors. The evidence was synthesized qualitatively according to the criteria of the World Cancer Research Fund and meta-analyzed. Results A total of nine RCTs met inclusion criteria; six were conducted during pregnancy, two during infancy, and one during both pregnancy and infancy. Meta-analysis showed that long chain n-3 fatty acid supplementation during pregnancy significantly reduced the risk of asthma/wheeze in the child (RR 0.62 [95% confidence interval 0.34–0.91], P = 0.005, I2 = 67.4%), but not other outcomes. Supplementation during lactation of infancy showed no effects on any outcome. The strength of evidence that long chain n-3 fatty acid supplementation during pregnancy reduces risk of asthma/wheeze in the offspring was considered limited – suggestive. No conclusion could be made for the effects of long chain n-3 fatty acid supplementation during pregnancy for other atopic diseases, or for supplementation during lactation or infancy for any outcome. Conclusion The intake of long chain n-3 fatty acid supplements during pregnancy may reduce the risk of asthma and/or wheeze in the offspring, but the strength of evidence is low. There is inconclusive evidence for the effects of long chain n-3 fatty acid supplements during pregnancy for other outcomes, as well as for supplementation during lactation or infancy.
Potential Contribution of Coastal Upwelling to Carbon Sink through Interaction between Cyanobacteria and Microbial Eukaryotes

Upwelling, a common oceanographic event, can make great contributions, directly or indirectly, to deep ocean carbon sequestration. However, the extent of its contribution indirectly depends on the composition of microbial communities and the interactions between bacterioplankton and other microorganisms. This study provides insights into the influence of upwelling on bacterioplankton at the whole community level and predicts their potential functional profiles. The α diversity of the bacterial community exhibited no significant differences between the upwelling area and non-upwelling area, while the community composition varied clearly in different habitats. Proteobacteria, Cyanobacteria, Bacteroidota, Firmicutes, and Actinobacteria were the five dominant phyla in all of the habitats. The proportions of members of Firmicutes were increased whereas Cyanobacteria were reduced in upwelling water. However, the percentage of Cyanobacteria was enhanced in the upwelling deep water. Functional genes that are involved in signal transductions, which belong to environmental information processing, were more active in upwelling surface water than in the other habitats. Closer and more complex relationships between bacterioplankton and microbial eukaryotes were found in the upwelling area, which altered with the variation of the external environmental conditions. Cyanobacteria showed a positive correlation with microbial eukaryotes in upwelling deep water. Combined with the high proportions of Cyanobacteria in upwelling deep water, this might be strong evidence that Cyanobacteria contribute to a deep ocean carbon sink. Overall, our study reveals the impacts of upwelling on the bacterial community composition, metabolic functions, and microbial interactions, which are significant to further understanding the carbon sink effects of upwelling.
Perceived Challenges Faced By Student-Teachers (Prospective Teachers) From Universities and Colleges in Ghana during Off-Campus Teaching Practice

The study explored perceived challenges faced by student-teachers during the off-campus teaching practice. A descriptive survey design was adopted for the study. The population for the study was all the student-teachers (300, 350, and 400 levels) from College of Education (Regular), University (Regular), University (Sandwich), and other modes of education. However, 135 student-teachers were randomly and conveniently sampled for data collection. The instrument used for the study was an adapted questionnaire. The instrument was validated from an expert perspective. Data to answer research questions were analysed using the means and standard deviations. The study found that student-teachers do not have personal challenges during their teaching practices. The study found that student-teachers do not have supervisory challenges during their teaching practices. The study also revealed that student-teachers do not face major challenges from their practicing schools during their teaching practices. It is recommended that Colleges of Education, Teacher Continuous Professional Development of the Universities, as well as Ghana Education Service should organise periodic workshops for student-teachers and in-service teachers on the selection of appropriate TLMs for various lessons.
An Elite Middle Bronze IIA Warrior Tomb from Yehud, Central Coastal Plain, Israel

A salvage excavation held at the city of Yehud (Israel) revealed an unusual burial of the Middle Bronze (MB) IIA period. The grave was isolated from other MB burials in the Yehud area and was exceptionally large and rich in terms of the types and diversity of burial offerings, which included pottery vessels, metal objects, and animal bones. An outstanding find among the burial goods was an anthropomorphic jug whose neck was shaped in the form of a seated figure supporting its head with the right hand, evoking the image of Rodin’s “Le Penseur. ” This paper presents the grave and offerings uncovered in the excavation and an interpretation of these finds, along with a discussion of the grave within the wider context of Middle Bronze Age burials in Yehud and beyond, suggesting it was associated with an elite warrior, who served most likely as a local leader.
An Overview of Missed Nursing Care and Its Predictors in Saudi Arabia: A Cross-Sectional Study

Background Nursing care is holistic, and missing any aspect of care can be critical to patients' health. However, due to the complex and intense nature of the nursing practice, nurses have to unintentionally prioritize some activities, forcing them to omit some aspects of nursing care. Aim To explore the dimensions of missed nursing care and its predictors within the Saudi Arabian healthcare system. Methods Quantitative, cross-sectional study used the MISSCARE survey by utilizing nonprobability convenience sampling to collect the data of 604 staff nurses working in inpatient wards in Jazan, Saudi Arabia. Results The overall mean of missed nursing care is (m = 1.37, SD = 0.45). Missed nursing care activities were mostly failure to attend interdisciplinary care conferences (m = 1.66, SD = 0.96) and patient ambulation thrice a day (m = 1.63, SD = 0.97). Missed nursing care was mainly caused by human resource shortage (m = 3.53, SD = 0.88). Missed nursing care is predicted by the turnover intention (B = 2.380, t = 3.829, p < 001) and job satisfaction (B = −0.864, t = −4.788, p < 001). Conclusion Although missed nursing care is evident in Saudi Arabia, it is significantly lower than the international rates, and it is mainly caused by labor resource shortage which directly influences nurses' job satisfaction and intention to leave. Optimizing the recruitment process, resource allocation and effective nurses' retention programs are proposed solutions that may be beneficial to mitigate missed nursing care.
Sensitization of Patient-Derived Colorectal Cancer Organoids to Photon and Proton Radiation by Targeting DNA Damage Response Mechanisms

Simple Summary Radiotherapy plays an important role in the treatment of colorectal cancer (CRC). Approximately one-third of patients with rectal cancer show a pathological complete response upon total neoadjuvant treatment. Patient-derived CRC organoids were investigated regarding their radiotherapeutic treatment response—both in terms of conventional photon irradiation, the combination thereof with chemotherapy, as well as proton irradiation. By inhibition of an important sensor molecule for DNA damage, which has been shown to be activated upon irradiation, radioresistant organoids could be resensitized. Abstract Pathological complete response (pCR) has been correlated with overall survival in several cancer entities including colorectal cancer. Novel total neoadjuvant treatment (TNT) in rectal cancer has achieved pathological complete response in one-third of the patients. To define better treatment options for nonresponding patients, we used patient-derived organoids (PDOs) as avatars of the patient’s tumor to apply both photon- and proton-based irradiation as well as single and combined chemo(radio)therapeutic treatments. While response to photon and proton therapy was similar, PDOs revealed heterogeneous responses to irradiation and different chemotherapeutic drugs. Radiotherapeutic response of the PDOs was significantly correlated with their ability to repair irradiation-induced DNA damage. The classical combination of 5-FU and irradiation could not sensitize radioresistant tumor cells. Ataxia-telangiectasia mutated (ATM) kinase was activated upon radiation, and by inhibition of this central sensor of DNA damage, radioresistant PDOs were resensitized. The study underlined the capability of PDOs to define nonresponders to irradiation and could delineate therapeutic approaches for radioresistant patients.