Miracle-dz/UniFAR-FTUs huggingface dataset:
A Comparative Analysis of Surgical Wound Infection Methods: Predictive Values of the CDC, ASEPSIS, and Southampton Scoring Systems in Evaluating Breast Reconstruction Surgical Site Infections

Infection is the most significant complication in breast reconstruction surgery. While the Center for Disease Control and Prevention (CDC) is the most prevalent tool for surgical site infection (SSI) diagnosis, ASEPSIS and Southampton scoring methods have been speculated to be more sensitive. The ASEPSIS scoring system previously demonstrated much better interrater reliability than the CDC. We sought to assess the predictive value of various wound scoring methods in breast reconstruction SSIs. A retrospective analysis of all single-institution breast reconstruction infections from January 2013 to June 2016 was performed. Patients’ postoperative wound-related complications were collected. Southampton, CDC, and modified ASEPSIS scores—extended to 30 postoperative days—were calculated. Relative predictive values for implant-based reconstruction were evaluated. Among the 22 reviewed cases, ASEPSIS scores greater than 30 resulted in a more than 50% rate of implant-based breast reconstruction failure. There was a significant positive correlation between ASEPSIS score and failure rate (P = .022). A Southampton classification of B—minor complication (60% failure)—had a greater associative risk of reconstruction failure than a classification of C—major complication (23% failure)—or classification of D—major hematoma (0% failure). The CDC score had no predictive value of success versus failure of reconstruction. While the CDC criteria and Southampton scoring systems demonstrated little clinical use, the ASEPSIS scoring system shows substantial predictive value for breast reconstruction SSIs. New procedure protocols should be implemented to require detailed surgical notes including the proportion of the wounds affected by inflammatory responses to allow for easier wound score calculation by these alternate scoring systems.
Large Scale Micropropagation of Quercus robur L. Using Adenine-Type Cytokinins and Thidiazuron to Stimulate Shoot Proliferation

Abstraet. High rates of oak shoot m,dtiplication were achieved on low salt nutrient media (BTM, WPM) supplemented with adenine type cytokinin PBA or BAP. Low concentration of PBA (0.2--0.6 mg 1-1) stimulated formation of a large number of axillary shoots and their elong&tion. Thidiazuron in very low concentration (0.001- 0.002 mg 1-1) promoted shoot proliferation, in high concentration stimulated formation of large callus. More than twelve thousand micropropagated shoots were rooted in low salt agar media supplemented with low concentration of auxin (IBA or NAA 0.2--0.5 mg 1~1). High rooting percentages (81%) were obtained. Survivs1 of the micropropagated plantlets transplanted into soil was high (78 ~/o). Micropropagated trees planted in the field withstood severe winter frostu without significant losses. At the end of the fifth growing season trees attained considerable sizo. A rapid vegetative propagation of selected trees of Quercus robur is very desirable for the acceleration of the tree improvement programs. In past years we have paid considerable attention to a rapid in vitro propagation of oak. We have succeeded in multiplication of oak shoots using nodal segments and shoot tips as initial explants (CHAL~PA 1979). In order to improve shoot multiplication rate new low salt nutrient media were developed (C~ALVPA 1981) which stimulated rapid growth and proliferation of axillary shoots. Our further experiments showed that various low salt media are suitable for promoting rapid shoot proliferation and rooting of Quercus robur (C~ALVPA 1983, 1984). Our first in vitro propagated trees of Quercus robur were planted in the field in 1980 and from that time micropropagated trees of Quercus rebut have been produced every year and planted in the field. For further improvement of oak shoot proliferation we have tested some new compounds which show a high cytokinin activity. The present communication describes the effects of different cytokinins on in vitro shoot multiplication of Quercus robur and the field growth of in vitro propagated trees.
Specificity of autoantibodies in autoimmune thrombocytopenia

In 42 patients with autoimmune thrombocytopenia (AITP) and a positive direct platelet suspension immunofluorescence test (PSIFT), the antigenic specificity of the autoantibodies was studied. Because the autoantibodies were often not detectable in the serum and additional HLA antibodies may disturb the reaction pattern with the platelet panel, we used eluates prepared from the patients' platelets for this study. Thirty-five patients had antibodies equally reactive with normal platelets, irrespective of their antigenic make-up, but not with the platelets from two Glanzmann's disease patients. Absorption and elution experiments in two patients showed that his was probably not due to the presence of a combination of anti-Zwa and anti-Zwb antibodies. Thus, the majority of autoantibodies against platelets seems to be directed against antigenic determinants not present on Glanzmann's disease platelets, but perhaps located on the platelet-membrane glycoproteins IIb and/or IIIa. In ten patients, antibodies of no, or still unknown, specificity were detected. Three of these had additional antibodies not reactive with the platelets of the two Glanzmann patients.
The Relationship Between Screen and Outdoor Time With Rates of Myopia in Spanish Children

Background: Nowadays, digital devices have become usual in children's lives around the world. Five percent of the children between 5 and 7 years old have their own smartphone and forty-two percent of them have their own tablet. This fact has produced a change in their lifestyle that can imply some risks, threats and/or opportunities. The light emitted by digital devices' screens could involve, among others, possible risks to children's vision. Methods: This study shows a detailed analysis of the vision of 7,497 children between 5 and 7 years old carried out in the “Annual school campaign for children's visual health” in Spain during the years 2016, 2017, and 2019. The study connects the results in the visual screening with children's lifestyle, taking into account both, the number of hours per day that they use all digital devices and the daily time of outdoor exposure. Results: The study shows that children with myopia have more screen time use and shorter outdoor activity time when compared to those without myopia (p < 0.01). Conclusions: Myopia in children is a public health problem and requires healthy lifestyle interventions at individual as well as at community level.
GENETIC ANALYSIS OF WEEVIL (COSMOPOLITES SORDIDUS) RESISTANCE IN AN F2 DIPLOID BANANA POPULATION

The East African highland bananas ( Musa spp . AAA), an important staple food in Uganda, are highly susceptible to the banana weevil ( Cosmopolites sordidus Germar). Sources of host plant resistance to the banana weevil exist in wild diploid bananas. The use of wild diploid bananas to improve East African highland bananas can be facilitated by studying genetics of host plant resistance of inter-diploid crosses. The objectives of this study were a) to identify segregating weevil resistance and agronomic traits in an F 2 diploid population, and, b) to determine the inheritance of banana weevil resistance and agronomic traits based on an F 2 banana diploid population. An F 1 population developed from Musa acuminata subsp. banksii acc. Kasaska (ITC0591) and M. acuminata subsp. microcarpa acc. Borneo (ITC0253) was selfed to generate an F 2 diploid population. The F 2 population was screened against weevil resistance and agronomic traits in the laboratory, pot and field experiments. There were significant differences ( P < 0.05) among the different genotypes for banana weevil resistance traits such as head capsule width, body length, body weight, larval mortality, total damage, peripheral damage, dead weevils and larvae retrieved. There were also significant differences ( P < 0.05) for agronomic traits such as inner corm hardness and total corm hardness. The histograms for the banana weevil resistance traits such as head capsule width, body length, body weight and larval mortality, total damage, peripheral damage, cross sectional inner and outer damage, larvae retrieved and dead weevils showed continuous distribution. Similarly, histograms for agronomic parameters such as height of plant at flowering and girth at 1 meter at flowering showed continuous distribution. The Chi-square test of goodness of fit indicated that weevil growth and damage parameters had significant modifications of the expected 9:3:3:1 ratio for two independent loci, thus suggesting epistasis affects their inheritance.
Centre-of-mass and minimal speed limits of the great hammerhead

The great hammerhead is denser than water, and hence relies on hydrodynamic lift to compensate for its lack of buoyancy, and on hydrodynamic moment to compensate for a possible misalignment between centres of mass and buoyancy. Because hydrodynamic forces scale with the swimming speed squared, whereas buoyancy and gravity are independent of it, there is a critical speed below which the shark cannot generate enough lift to counteract gravity, and there are anterior and posterior centre-of-mass limits beyond which the shark cannot generate enough pitching moment to counteract the buoyancy–gravity couple. The speed and centre-of-mass limits were found from numerous wind-tunnel experiments on a scaled model of the shark. In particular, it was shown that the margin between the anterior and posterior centre-of-mass limits is a few tenths of the product between the length of the shark and the ratio between its weight in and out of water; a diminutive 1% body length. The paper presents the wind-tunnel experiments, and discusses the roles that the cephalofoil and the pectoral and caudal fins play in longitudinal balance of a shark.
Ocular Side Effects of EGFR-Inhibitor ABT-414 in Recurrent Glioblastoma: A Long-Term Safety Study

This study aimed to prospectively evaluate, on a long-term basis, corneal side effects secondary to compassionate administration of epidermal growth factor receptor (EGFR) inhibitor depatuxizumab mafodotin (ABT-414) in patients affected by EGFR-amplified recurrent glioblastoma. Fifteen patients with a median follow-up of 4.3 months after treatment discontinuation were enrolled. Each patient underwent full ophthalmologic examination including in vivo corneal confocal microscopy (CCM). No CTCAE grade 4 toxicity and four (27%) grade 3 toxicities were documented during treatment. Ocular symptoms (blurred vision, eye pain, photophobia) were experienced by all patients, reaching maximal severity after the second ABT-414 infusion, with persistence until treatment discontinuation. During treatment, CCM documented specific changes in the corneal epithelium and in the sub-basal nerve plexus layer fibers of all eyes. The median time of symptoms resolution after treatment discontinuation ranged from 38 days (eye pain) to 53 days (photophobia). The median time of signs resolution ranges from 14 days (corneal ulcer) to 38 days (superficial punctate epitheliopathy, corneal stroma edema and intraepithelial cysts). ABT-414 corneal side effects are detectable in all treated patients. Related symptoms are gradually experienced by all patients during treatment and although reversible, they are characterized by a relative prolonged persistence after treatment discontinuation.
Bioinformatics-Based Activities in High School: Fostering Students’ Literacy, Interest, and Attitudes on Gene Regulation, Genomics, and Evolution

The key role of bioinformatics in explaining biological phenomena calls for the need to rethink didactic approaches at high school aligned with a new scientific reality. Despite several initiatives to introduce bioinformatics in the classroom, there is still a lack of knowledge on their impact on students’ learning gains, engagement, and motivation. In this study, we detail the effects of four bioinformatics laboratories tailored for high school biology classes named “Mining the Genome: Using Bioinformatics Tools in the Classroom to Support Student Discovery of Genes” on literacy, interest, and attitudes on 387 high school students. By exploring these laboratories, students get acquainted with bioinformatics and acknowledge that many bioinformatics tools can be intuitive for beginners. Furthermore, introducing comparative genomics in their learning practices contributed for a better understanding of curricular contents regarding the identification of genes, their regulation, and how to make evolutionary assumptions. Following the intervention, students were able to pinpoint bioinformatics tools required to identify genes in a genomics sequence, and most importantly, they were able to solve genomics-related misconceptions. Overall, students revealed a positive attitude regarding the integration of bioinformatics-based approaches in their learning practices, reinforcing their added value in educational approaches.
Elevated Exhaustion Levels of NK and CD8+ T Cells as Indicators for Progression and Prognosis of COVID-19 Disease

Background Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) induced Coronavirus Disease 2019 (COVID-19) has posed a global threat to public health. The immune system is crucial in defending and eliminating the virus and infected cells. However, immune dysregulation may result in the rapid progression of COVID-19. Here, we evaluated the subsets, phenotypic and functional characteristics of natural killer (NK) and T cells in patients with COVID-19 and their associations with disease severity. Methods Demographic and clinical data of COVID-19 patients enrolled in Wuhan Union Hospital from February 25 to February 27, 2020, were collected and analyzed. The phenotypic and functional characteristics of NK cells and T cells subsets in circulating blood and serum levels of cytokines were analyzed via flow cytometry. Then the LASSO logistic regression model was employed to predict risk factors for the severity of COVID-19. Results The counts and percentages of NK cells, CD4+ T cells, CD8+ T cells and NKT cells were significantly reduced in patients with severe symptoms. The cytotoxic CD3-CD56dimCD16+ cell population significantly decreased, while the CD3-CD56dimCD16- part significantly increased in severe COVID-19 patients. More importantly, elevated expression of regulatory molecules, such as CD244 and programmed death-1 (PD-1), on NK cells and T cells, as well as decreased serum cytotoxic effector molecules including perforin and granzyme A, were detected in patients with COVID-19. The serum IL-6, IL-10, and TNF-α were significantly increased in severe patients. Moreover, the CD3-CD56dimCD16- cells were screened out as an influential factor in severe cases by LASSO logistic regression. Conclusions The functional exhaustion and other subset alteration of NK and T cells may contribute to the progression and improve the prognosis of COVID-19. Surveillance of lymphocyte subsets may in the future enable early screening for signs of critical illness and understanding the pathogenesis of this disease.
A Measure of Service Quality in the Grocery Stores

The main purpose of this study is to increase the understanding of the perceived service quality of the customer within grocery retailing from an Indian perspective. In this dissertation, data were collected from 403 customers who buy grocery from Big Bazaar and Reliance Fresh during February–July 2017 from Bhubaneswar and Cuttack. A quantitative approach using Statistical Package for the Social Science (SPSS) version 20 is used, which caters to the exploratory nature of the work. Statistical techniques such as exploratory factor analysis, multiple regression, t-test and ANOVA have been used to test the hypotheses and answer the research questions. It can be inferred from this study that consumer behaviour is dependent on the demographic factors. Differences were also found with regard to the impact of service quality on the satisfaction and the loyalty of the customers. This research adds to the study on service quality in the grocery business of the global market by enriching the content of service quality dimensions applicable to the Indian grocery sector. Six key dimensions in the grocery sector have been identified. This will deepen the understanding of the explored factors of service quality, which can then be applied to the grocery stores.
Recommender System Based on User's Tweets Sentiment Analysis

With the ever-growing volume of online information, recommender systems have been an effective strategy to overcome such information overload. The utility of recommender systems cannot be overstated, given its widespread adoption in many web applications, along with its potential impact to ameliorate many problems related to over-choice. Nowadays, people from all around the world use social media sites to share information. Twitter, for example, is a social network in which users send, read posts known as ‘tweets’ and interact with different communities. Users share their daily lives, post their opinions on everything such as brands and places. Social influence plays an important role in product marketing. However, it has rarely been considered in traditional recommender systems. In this paper, we present a new paradigm of e-commerce recommender systems, which can utilize information in social networks. In this study, we have combined sentiment analysis of twitter data with the collaborative filtering in order to increase system accuracy. The proposed system uses lexical approach to analyze sentiment. In order to design the recommender system, we have replaced the missing values of the ratings matrix with the averages of the ratings assigned to the items, to solve the sparsity and cold-start problems inherent in collaborative filtering. The results show that our proposed method improves CF performance. In this experiment we demonstrate how relevant social media can be for recommender systems.
A new Hymedesmia (Demospongiae, Poecilosclerida) with large sigmas off western Sweden

Hymedesmia (Hymedesmia) lindstroemae sp. nov. collected at 178–210 m depth off the western Swedish coast is described. This encrusting sponge is notably characterized by its unusually large sigmas. This new species brings the number of Hymedesmia (Hymedesmia) species in Swedish waters to 30. A key for all the North Atlantic Hymedesmia (Hymedesmia) species with sigmas (32 species) is included.
The ammonite septum is not an adaptation to deep water: re-evaluating a centuries-old idea

The shells of ammonoid cephalopods are among the most recognizable fossils, whose fractally folded, internal walls (septa) have inspired many hypotheses on their adaptive value. The enduring explanation for their iterative evolution is that they strengthen the shell against pressure at increasing water depths. The fossil record does not definitively support this idea and much of the theoretical mechanical work behind it has suffered from inaccurate testing geometries and conflicting results. By using a different set of mathematical methods compared with previous studies, I generate a system of finite-element models that explore how different parameters affect the shell's response to water pressure. Increasing the number of initial folds of the septa ultimately has little to no effect on the resulting stress in the shell wall or the septum itself. The introduction of higher-order folds does reduce the tensile stress in the shell wall; however, this is coupled with a higher rate of increase of tensile stress in the septum itself. These results reveal that the increase in complexity should not be expected to have a significant effect on the shell's strength and suggests that the evolution of ammonitic septa does not reflect a persistent trend towards deeper-water habitats.
The Influence of E-Service Quality on Trust and Intention to Conduct Positive E-Word-of-Mouth in Telecommunication Industry

A company website serves at least two purposes, first, for e-commerce or e-banking transactional activities and second for informing products and services offered by the company to customers, i.e., content-driven. This study examines the effect of electronic service quality toward customer satisfaction and attitude by accessing a content-driven telecommunication website as well as to assess the influence toward trust and intention to conduct eWOM (electronic Word-of-Mouth). This research collects data from 200 respondents of Gene Y consumers who have accessed a telecommunication website. Structure equation modeling is employed to verify and validate the research model. The results confirm the effects showing that e-Service quality affects both customer satisfaction and attitude toward a website, then customer attitude toward website affects trust toward the provider. Moreover, customer intention to positive eWOM is affected both by customer attitude toward website and customer trust toward the provider. However, customer satisfaction does not affect trust and intention to positive eWOM toward providers significantly. The research gleans insights into a company that can use the informational website to improve the customer attitude and trust that, in turn, will increase their intention in making positive eWOM.
Nutritive value of clipped and grazed range forage samples.

the same for all growth stages, 400 to 500 ppm nitrate-N, when recently matured blade tissue was analyzed (Fig. 1, 2, and 3). Shoots were as good as recently matured blades for determining the critical concentration at the early vegetative growth stage. However, as the plants matured, the shoots became less reliable indicators of the N status of the grass (Fig. 3 and 4). The critical concentrations for the shoots were 400, 600, and 1300 ppm nitrateN, respectively, for the early vegetative, late vegetative, and late boot growth stages. The critical concentration for the shoots changed as the plants matured because the shoot composition was so dissimilar. An example of this dissimilarity was when the plants were in the late boot growth stage, the shoot samples were composed of immature seed heads, various stem sections, and leaves ranging from immature to senescent. In contrast, recently matured blades were reliable indicators of the N status of the grass at all growth stages because these blades were anatomically uniform and were the same physiological age regardless of plant maturity. The critical concentration of recently matured blade tissue was therefore similar, 400 to 500 ppm nitrate-N, at all growth stages. This critical nitrate-N concentration should be substantiated by further research under various