Miracle-dz/UniFAR-FTUs huggingface dataset:
Assessment of soil organic carbon stocks in the Limpopo National Park: from legacy data to digital soil mapping

In 2001, Mozambique declared an area known as “Coutada 16” (hunting zone) the Limpopo National Park (LNP), which forms part of a trans-frontier park with South Africa and Zimbabwe. The park provides ecosystem services and supports the livelihoods of thousands people living in the many communities within its boundaries, which were planned for relocation outside the park. These moves were expected to result in major land use changes, both in terms of vegetation and wildlife, affecting soil quality in and around the LNP, including in resettlement areas. Therefore, this study aimed at estimating soil organic carbon (SOC) stocks in the Limpopo National park as an indicator of livelihoods and ecosystem function. The estimation of SOC stocks was first attempted from legacy data then by both measure-andmultiply and digital soil mapping (DSM) based on a new sampling plan. Along this study issues of legacy data renewal quality, mapping data-poor and poorly-accessible areas, time-consuming and costly traditional method for SOC laboratory determination as well as uncertainty and reliability of SOC stocks estimates from different methods were also investigated. Overall this research provided (1) a guiding framework and quantitative measures for evaluation of renewed legacy survey and as such enabled an informed qualitative and quantitative SOC stocks estimation, (2) a cost-effective methodology for mapping SOC in data-poor, poorly-accessible areas following a DSM approach, (3) a rapid, cost-effect, non-destructive and pollutant-free Near-Infrared a calibration model for the determination of SOC in LNP and, (4) SOC stocks estimates, its uncertainty and reliability. Despite the high uncertainty of the estimates, which limit its use in baseline studies, achieved SOC stocks estimates are, in general, consistent with of SOC stocks estimates in the literature for similar soils in comparable environmental conditions in southern Africa.
A three-year overview of the pattern and outcome of medical conditions in the medical wards of Federal Medical Centre

INTRODUCTION: Hospital admissions reflect the pattern of illnesses in society, and itsdocumentation in various localities may provide clues on decision-making and implementationsin the health sector. This study aimed to ascertain the reasons for admission and outcome in themedical wards of the Federal Medical Centre, Yenagoa, Nigeria.METHODS: The medical records of all patients admitted into the medical wards during thestudy were retrospectively reviewed. Disease classification was done according to the ICD-10classification system. Relevant data were obtained from the admission and discharge registersand were analyzed using Statistical Package for Social Sciences version- 22.RESULTS: A total of 1,782 subjects comprising 933 males (52.4%) and 849 females (47.6%) wererepresented in the final data analysis. The majority of the admitted patients were in their 6th and7th decade of life (18.5% and 18.6%, respectively). Cardiovascular diseases were the commonestindication for annual medical admission, with a cumulative frequency of 35.5%. Stroke andheart failure were the most common cardiovascular diseases. Infectious diseases were thesecond leading cause of medical admission (19.5%). The least common medical disorders wererheumatological dermatological and toxicological conditions representing 0.5%, 0.2%, and 0.2%,respectively, of all medical admissions. The overall mortality during the study period is 16.5%,with malignant diseases being the leading cause of death.CONCLUSION: This study reflects the epidemics of non-communicable diseases in developingcountries and the need for policymakers to be aware of this trend without neglecting to preventinfectious diseases, whose burden is still high.
A Greater Increase in Complement C5a Receptor 1 Level at Onset and a Smaller Decrease in Immunoglobulin G Level after Recovery in Severer Coronavirus Disease 2019 Patients: A New Analysis of Existing Data with a New Two-Tailed t-Test

Simple Summary It is important to know exactly the difference in changes in Complement C5a Receptor 1 (C5aR1) levels at onset and in Immunoglobulin G (IgG) levels after recovery between severe and non-severe coronavirus disease 2019 (COVID-19) patients to reduce the severity of the disease and prevent reinfection with severe acute respiratory syndrome coronavirus 2. We found that some of these changes in C5aR1 and IgG levels over time were dependent on their initial levels and not suitable for analysis by conventional statistical tests. We developed new t-tests that correctly examine the above changes. Our new t-test suggested a greater increase in C5aR1-levels at onset and a smaller decrease in IgG-levels after recovery in COVID-19 patients than non-COVID-19 patients, which were not detected by conventional statistical tests. Thus, the clinical trials should be analyzed with not only conventional statistical tests but also our new t-test. Abstract (1) Background: It is our purpose to identify the differences in the changes in Complement C5a receptor 1 (C5aR1) levels showing the degree of inflammation at onset and Immunoglobulin G (IgG) levels showing the extent of survival of the virus fragments after recovery between coronavirus disease 2019 (COVID-19) and pneumonia coronavirus disease (non-COVID-19) for saving patients’ lives. (2) Methods: First, the studies showing these markers’ levels in individual patients before and after the passage of time were selected from the PubMed Central® databases with the keywords (((COVID-19) AND individual) NOT review) AND C5a/IgG. Then, no changes in these markers’ levels with conventional analyses were selected from the studies. Finally, the no changes were reexamined with our new two-tailed t-test using the values on the regression line between initial levels and changed levels instead of the mean or median of changed levels as the expected values of changed levels. (3) Results: Not conventional analyses but our new t-test suggested a greater increase in C5aR1-levels at onset and a smaller decrease in IgG-levels after recovery in COVID-19 patients than non-COVID-19 patients. (4) Conclusion: Our new t-test also should be used in clinics for COVID-19 patients.
Exploring the Effect of Learning Motivation and Self-Regulated Learning Climate on Undergraduates’ Self-Regulated Learning in Higher Education

Self-regulated learning (SRL) has numerous benefits for students. For this reason, it is necessary to understand what factors can affect SRL. The literature has indicated that many factors can influence SRL as a whole. However, few studies have investigated the relationship between factors that can affect SRL and different phases of SRL. This research aims to investigate the influence of learning motivation and self-regulated learning climate on three phases of SRL (forethought, performance, and self-reflection) in higher education context. Thirteen Chinese undergraduates participated in semi-structured interviews. The results reveal that both learning motivation and self-regulated learning climate have significant impact on forethought, performance, and self-reflection. This study also demonstrates that personality may play a role of mediator in the effect of learning motivation on SRL. The influence of self-regulated learning climate on SRL is related to the level of interaction between teachers and students. These findings can help to further develop undergraduates’ SRL ability.
Frequent respiratory events in postoperative patients aged 60 years and above

: There is limited information on the occurrence of respiratory events in postoperative patients after discharge from the postanesthesia care unit. We studied the respiratory rate (RR) of 68 patients aged 60 years and above during the first 6 hours following elective surgery under general anesthesia to assess the frequency of respiratory events in the care unit and on the ward. RR was derived from the continuous RR counter RespiR8, measuring RR by quantifying the humidity of exhaled air. One-minute-averaged RRs were collected and analyzed to assess the frequency of postoperative bradypnea (RR 1–6 breaths/minute) and apnea (cessation of inspiratory flow $ 60 seconds). Values were median (interquartile range) or mean (SD). The median RR was 13 (10–15) breaths/minute. In the 6-hour postoperative period, 78% and 57% of patients experienced at least one bradypnea or apnea event, respectively. A median of ten (3.5–24) bradypnea and three (1–11) apnea events were detected per patient. The occurrence of respiratory events in the postanesthesia care unit (PACU) was a predictor of events on the ward (bradypnea, r 2 = 0.4, P , 0.001; apnea, r 2 = 0.2, P , 0.001). Morphine consumption correlated weakly with respiratory events in the PACU, but not on the ward. Patients with apnea had significantly larger neck circumference than patients without (39.6 [0.7] versus 37.4 [0.8] cm, P , 0.05). Bradypneic or apneic respiratory events are frequent in postoperative elderly patients and even occur relatively late after surgery. Continuous respiratory monitoring on the ward, especially in patients with risk factors, such as early occurrence of events, opioid use, and larger neck circumference, is likely warranted.
Research into the mechanism of intervention of Wenjing decoction in endometriosis based on network pharmacology and molecular docking technology

Background: Endometriosis (EMs) is a frequent disease in women and is the principal cause of infertility and dysmenorrhea. Due to its high recurrence rate and serious complications, more research on EMs is needed. We used network pharmacology and molecular docking technology to predict the key active components, targets, and signaling pathways of Wen Jing decoction (WJD) in the treatment of EMs. Methods: The components and targets of WJD were collected and identified using the Traditional Chinese Medicine Systems Pharmacology Database and BATMAN-TCM. The EMs targets were obtained from GeneCards, OMIM, TTD, Kyoto encyclopedia of genes and genomes (KEGG) and GAD Databases; the Venny diagram was used to analyze the overlap between the targets of WJD and EMs; use Cytoscape 3.8. 2 software to build a drug active ingredient–target protein interaction network; after downloading the data from the String online database, Cytoscape 3.8. 2 software was used to draw the intersection target protein–protein interaction network diagram. Finally, microbiotic information mapping was used to analyze gene ontology function enrichment and KEGG pathway enrichment. Molecular docking was used to predict the binding affinity of the components of WJD to the targets of EMs. Results: Seventy-eight active ingredients of WJD were screened, corresponding to 108 targets, 2626 EMs-related targets and 124 intersection targets. The results of gene ontology functional enrichment analysis showed that WJD could affect 709 biological processes, 131 molecular functions and 54 cell composition. The enrichment analysis of KEGG pathway yielded 185 pathways. The treatment of EMs by WJD has the characteristics of multiple targets and multiple pathways. Molecular docking with the AutoDock Vina platform found that 5 active ingredients of WJD were successfully docked with 6 common targets. Conclusion: Based on network pharmacology and molecular docking, WJD was found to act on EMs through multi-targets and related signaling pathways.
Isolation and Characterisation of Human-Derived blaKPC-3-Producing Salmonella enterica Serovar Rissen in 2018

In this study, we describe a Salmonella enterica serovar (S.) Rissen strain with a reduced susceptibility to meropenem, isolated from a urinary infection in an 89-year-old woman in 2018 during activity surveillance in Italy (Enter-Net Italia). The genomic characteristics, pathogenicity, and antimicrobial resistance mechanisms were investigated via a genomic approach. Antimicrobial susceptibility testing revealed a “susceptible, increased exposure” phenotype to meropenem in the S. Rissen strain (4_29_19). Whole-genome sequencing (WGS) was performed using both the NovaSeq 6000 S4 PE150 XP platform (Illumina, San Diego, CA, USA) and MinION (Oxford Nanopore). The S. Rissen 4_29_19 strain harboured two plasmids: a pKpQIL-like plasmid carrying the blaKPC-3 resistance gene in a Tn4401a transposon (pKPC_4_29_19), and a ColE-like plasmid (p4_4_29_19) without resistance genes, highly prevalent among Enterobacterales. Comparative analysis revealed that the pKPC_4_29_19 plasmid was highly related to the pKpQIL reference plasmid (GU595196), with 57% coverage and 99.96% identity, but lacking a region of about 30 kb, involving the FIIK2 replicon region and the entire transfer locus, causing the loss of its ability to conjugate. To our knowledge, this is the first time that a pKpQIL-like plasmid, carrying blaKPC-3, highly diffused in Klebsiella pneumoniae strains, has been identified in a Salmonella strain in our country. The acquisition of blaKPC genes by Salmonella spp. is extremely rare, and is reported only sporadically. In zoonotic bacteria isolated from humans, the presence of a carbapenem resistance gene carried by mobile genetic elements, usually described in healthcare-associated infection bacteria, represents an important concern for public health.
Forced Hepatic Expression of NRF2 or NQO1 Impedes Hepatocyte Lipid Accumulation in a Lipodystrophy Mouse Model

Lipodystrophy is a disorder featuring loss of normal adipose tissue depots due to impaired production of normal adipocytes. It leads to a gain of fat deposition in ectopic tissues such as liver and skeletal muscle that results in steatosis, dyslipidemia, and insulin resistance. Previously, we established a Rosa NIC/NIC::AdiCre lipodystrophy model mouse. The lipodystrophic phenotype that included hepatomegaly accompanied with hepatic damage due to higher lipid accumulation was attenuated substantially by amplified systemic NRF2 signaling in mice with hypomorphic expression of Keap1; whole-body Nrf2 deletion abrogated this protection. To determine whether hepatic-specific NRF2 signaling would be sufficient for protection against hepatomegaly and fatty liver development, direct, powerful, transient expression of Nrf2 or its target gene Nqo1 was achieved by administration through hydrodynamic tail vein injection of pCAG expression vectors of dominant-active Nrf2 and Nqo1 in Rosa NIC/NIC::AdiCre mice fed a 9% fat diet. Both vectors enabled protection from hepatic damage, with the pCAG-Nqo1 vector being the more effective as seen with a ~50% decrease in hepatic triglyceride levels. Therefore, activating NRF2 signaling or direct elevation of NQO1 in the liver provides new possibilities to partially reduce steatosis that accompanies lipodystrophy.
Strontium isotopes in conodonts : Devonian-Carboniferous transition, the northern Rhenish Slate Mountains, Germany

A set of 51 87Sr/86Sr isotope measurements on biostratigraphically dated conodonts and brachiopods from the Devonian-Carboniferous transition of the northern Rhenish Slate Mountains yields a high resolution record for the 87Sr/86Sr isotope curve. The sections Hasselbachtal, Oberr6dinghausen, Ose and Riescheid at the Remscheid-Altena Anticline were selected because of their excellent stratigraphic control and a low degree of diagenesis. However, trace element studies and XRD analysis show that the francolite of conodonts, an unstable end-member in the system francolite-fluorapatite, is prone to diagenetic alteration. 87Sr/86Sr of unaltered low Mg calcite of contemporaneous brachiopods corroborate a distinct enrichment in radiogenic 87Sr in the conodonts. The discussed 87Sr/86Sr curve is therefore a secondary curve that nevertheless preserves to some degree the pattern of the original Sr paleo-seawater curve. The pattern of 3rd-order isotopic variations reaches its radiogenic maximum near the Devonian-Carboniferous boundary, coincident with a regression maximum. The biostratigraphic correlation of the sections Hasselbachtal, Oberr6dinghausen and Ose is confirmed by 87Sr/86Sr isotope stratigraphy. New conodont data show that the praesulcata Zone can be recognized in the Wocklum Limestone at the Oberr6dinghausen and Hasselbachtal sections.
Output Feedback Consensus for Networked Heterogeneous Nonlinear Negative-Imaginary Systems With Free-Body Motion

This article provides a protocol to address the robust output feedback consensus problem for networked heterogeneous nonlinear negative-imaginary (NI) systems with free body dynamics. We extend the definition of nonlinear NI systems to allow for systems with free-body motion. A new stability result is developed for the interconnection of a nonlinear NI system and a nonlinear output strictly negative-imaginary (OSNI) system. Also, a class of networked nonlinear OSNI controllers is proposed to achieve output feedback consensus for heterogeneous networked nonlinear NI systems. We show that in this control framework, the system outputs converge to the same limit trajectory. This consensus protocol is illustrated by a numerical example.
Potential Role of GGBS and ACBFS Blast Furnace Slag at 90 Days for Application in Rigid Concrete Pavements

Incorporating blast furnace slag into the composition of paving concrete can be one of the cost-effective ways to completely eliminate by-products from the pig iron production process (approximately 70% granulated slag and 30% air-cooled slag). The possibility to reintroduce blast furnace slag back into the life cycle will provide significant support to current environmental concerns and the clearance of tailings landfills. Especially in recent years, granulated and ground blast furnace slag (GGBS) as a substitute for cement and air-cooled blast furnace slag (ACBFS) aggregates as a substitute for natural aggregates in the composition of concretes have been studied by many researchers. But concrete compositions with large amounts of incorporated blast furnace slag affect the mechanical and durability properties through the interaction between the slag, cement and water depending on the curing times. This study focuses on identifying the optimal proportions of GGBS as a supplementary cementitious material (SCM) and ACBFS aggregates as a substitute to natural sand such that the performance at 90 days of curing the concrete is similar to that of the control concrete. In addition, to minimize the costs associated with grinding GGBS, the hydration activity index (HAI) of the GGBS, the surface morphology, and the mineral components were analyzed via X-ray diffraction, scanning electron microscopy (SEM), energy dispersive spectrometry (EDX), and nuclear magnetic resonance relaxometry (NMR). The flexural strength, the basic mechanical property of road concretes, increased from 28 to 90 days by 20.72% and 20.26% for the slag concrete but by 18.58% for the reference concrete. The composite with 15% GGBS and 25% ACBFS achieved results similar to the reference concrete at 90 days; therefore, they are considered optimal percentages to replace cement and natural sand in ecological pavement concretes. The HAI of the slag powder with a specific surface area equivalent to that of Portland cement fell into strength class 80 at the age of 28 days, but at the age of 90 days, the strength class was 100. The results of this research present three important benefits: the first is the protection of the environment through the recycling of two steel industry wastes that complies with European circular economy regulations, and the second is linked to the consequent savings in the disposal costs associated with wastefully occupied warehouses and the savings in slag grinding.
The Effect of Experience and Complexity of The Technology Acceptance Model (TAM) on Accepting Applications (E-PKH) In East Java

The purpose of this study is to examine and analyze the effect of experience and complexity of TAM on the EPKH application system used to report data at the Ministry of Social Affairs. This research is a quantitative study using data collection methods by distributing questionnaires to 150 respondents, namely social assistants in East Java. This type of research is explanatory research, the determination of the sample is done by the non-probability sampling technique and using a purposive sampling method. The collected data is then tested and analyzed using the Smart PLS program. The results showed that experience had no significant effect on perceived usefulness, while experience had a significant effect on perceived ease of use. Complexity also has a significant effect on perceived usefulness. Perceived ease of use has a significant effect on perceived usefulness, perceived usefulness has a significant effect on the intention to use and intention to use significantly affects real use.
Effect of spacing and fertilizer on yield of rainfed chilli in sub-montane zone of Maharashtra

An application of 150 kg N + 37.5 kg P 2 O 5 gave significantly highest dry chilli yield (2104 kg/ha) than rest of the treatments and was on par with 200 kg N + 50 kg P 2 O 5 /ha. However, spacing and fertilizer interactioneffects were not significant. The yield attributing characters viz., plant spread, number of fruit/plant, fruit lenght and yield/plant were maximum when crop was fertilized with 200 kg N + 50 kg P 2 O 5 /ha.
‘Khoisan’ linguistic classification today

Proposed by Greenberg (1950, 1963) as a language family, the currently available evidence indicates that ‘Khoisan’ in a linguistic sense can be viewed, at best, as a negative entity. It comprises a diverse range of languages in southern and eastern Africa which share the typological feature of phonemic clicks, yet cannot all be related genealogically to each other or any established lineage. This makes them different from other languages with a similar areal and typological profile which belong to the Bantu (Niger-Congo) and Cushitic (Afro-Asiatic) language families. This chapter attempts to give the state of the art about the inventory of Khoisan languages and the different types of linguistic classifications applied to them, namely within typological, areal, and historical-comparative linguistics. In addition, this introduction serves to provide a general background for the other contributions to this volume. Since these all address outstanding issues of genealogical and areal relations between Khoisan languages and peoples of southern Africa in particular, they are also embedded by the introduction within the complex problem of evaluating the population history of the Kalahari Basin before the Bantu expansion from a linguistic, anthropological, and genetic perspective.