Miracle-dz/UniFAR-FTUs huggingface dataset:
Digital Health in Children’s Oral and Dental Health: An Overview and a Bibliometric Analysis

Digital health technologies can widely increase access to oral health solutions and can make them easier to use and more accessible at all primary, secondary, and tertiary levels. This study aims to present a bibliometric analysis of published literature to identify the content, trends, and context of digital health technology use in children’s oral and dental health. After finalising the research question, the Scopus database was used to search systematically for related keywords from 1997 to 2022. The PRISMA methodology applied for systematic reviews was adopted to refine search results. VOS viewer software was applied to illustrate the topics and trends of digital health technology involved in children’s oral and dental health. An increase in use of the digital technologies was appeared in the index keywords after 2005. Computer-assisted therapy/surgery, computer simulation, computer program, image processing, nuclear magnetic resonance (NMR) imaging, and audio-visual equipment were more used index keywords in children’s dental care re-search from 2005–2015. Telemedicine, mobile application, virtual reality, and medical information were reported with the index keywords of dental caries, dental procedures, and dental anxiety after 2015. The study also identified a gap in the published literature in applying newer digital technologies, such as the Internet of Things (IoT) and gamification, in oral and dental health research and practice. There is a growing tendency to use digital technologies in children’s oral and dental health in recent years. Although the types and categorisations of the technology are typically diverse during the timeframe and by the area of dental services and oral health, identifying and categorizing these technologies based on oral health services could familiarise oral health policymakers with the application of the technology and help them design technology-based interventions to improve children’s oral health.
MBSE Driven Simulation of a Mid-Size Emergency Department Operation

Elshal, Mohamed M.S.M.E, Purdue University, December 2017. MBSE Driven Simulation of a Mid-Size Emergency Department Operation. Major Professor: Hazim El-Mounayri. Healthcare system in the United States faces multiple issues including quality, rising cost and outcome of the healthcare care delivery process. Systems engineering methodologies and tools have been proposed to address the complexity of healthcare delivery processes as well as the challenges facing the industry, including emergency departments. However, very few initiatives have considered such promising methodology to address the current limitations and improve the quality of care. The objective of this work is to develop and validate an innovative framework based on model-based systems engineering (MBSE) and discrete-event simulation (DES) to accurately model patient flow and predict resource utilization at a midsize emergency department. MBSE framework is developed using OMG systems modeling language (SysML); which provides a better understanding of the system, supports multiple system views, and enhances the verification and validation process. Data protocols are implemented to define data inputs and requirements. Time studies are conducted inside the ED to collect patient and human resource processing time data to run the simulation. Two discrete-event simulation models were implemented to evaluate the key performance measures of the ED system. Results are validated by comparing the output behavior of the model to the output behavior of the ED system using different data sources. The resulting simulation platform is able to predict human resources utilization, patient throughput and length of stay (LOS); in order to support clinical decision making (e.g. resource allocation) and improve the outcome of the emergency care delivery process.
#Selfies With a Mask On: Comparing Self-Presentation of Athletes From the U.S. and China in the 2020 Tokyo Olympics

The purpose of this study is to explore Chinese and U.S. athlete self-presentation in the 2020 Tokyo Olympics. By examining 1200 photographs posted by Olympians on social media, this study finds that (a) male athletes feature themselves in more revealing clothes than female athletes, (b) Chinese athletes actively show more nationalistic notions compared to their U.S. counterparts, and (c) U.S. female athletes are involved in more subordinating behaviors than Chinese female athletes. This study underlines how the intersection of gender, nationalism, and culture influences athlete social media self-presentation in the global pandemic context. Possible explanations and implications are discussed.
Weed management in rainfed lowland rice ecology in Nigeria – challenges and opportunities

Abstract Developing an effective weed management strategy is crucial to sustainable rice production in Nigeria. Rainfed lowland ecology contributes significantly to the volume of rice cultivated in terms of yield and land acreage. Nevertheless, increased weed infestation remains one of the major production constraints. This review highlights the strength and weaknesses of weed management practices in rainfed lowland ecology and research gaps, and examines the potential for developing a sustainable weed management strategy for lowland rice. In this review, a rainfed lowland situation is described (where water is limited) to engage flooding as a potential weed control option, due to the undulating land terrains. Effective weed management begins with creating a weed-free environment at the critical crop growth stages, such that broadcasted or transplanted rice seedlings can efficiently use water, nutrients, and light. Sustainable weed management practices in Nigerian lowland ecology would therefore imply that farmers begin to incorporate crop rotation to suppress problem weeds in continuous rice cropping systems; adopt conventional or minimum tillage to enhance herbicide efficacy and early establishment of rice; adopt weed-competitive and high-yielding cultivars; and practice appropriate spacing, seeding rate, and seeding methods that can support easy adoption of mechanical weeders and optimum plant population to suppress weed pressure at a later growth stage. This is feasible where farmers are supported with infrastructure, farm machinery, and other necessary inputs. Future research should engage lowland rice farmers in specific agroecological zones. Nomenclature: Rice; Oryza sativa L.
Fear of COVID-19 and academic stress among Palestinian university students during the pandemic: the mediating role of mental health

ABSTRACT The widespread Coronavirus pandemic has disrupted life for students and institutions worldwide. Such impacts may have affected the students' academic performance and mental health. In the current study, we aimed to explore the mediating role of mental health between fear of COVID-19 and academic stress among Gaza's university students during the COVID-19 outbreak. The sample consisted of 315 participants, of which 230 (73%) were females. The Fear of COVID-19 Scale, Depression Anxiety Stress Scale, Symptoms Checklist-10 and Academic Stress Scale were used. Fear of COVID-19 was found to be significantly positively correlated with depression, anxiety, stress and academic stress. Also, mental health was found to play a mediating role between fear of COVID-19 and academic stress.
Citation Analysis of Chemistry Doctoral Dissertations: An Ohio State University Case Study.

A citation analysis of dissertations accepted in the Department of Chemistry at The Ohio State University between 1996-2000 was performed as a way to determine material use. The 30 dissertations studied generated a total of 3,704 citations. Types of materials cited, currency of literature, and dissertation topics were all analyzed. The current results corroborate past research by other authors. Journal articles were cited more frequently than monographs: 85.8% of the citations were journal articles and 8.4% of the citations were monographs. The results of this study may be used to assist OSU and other universities in chemistry collection development.
Effects of Land-Use Change on the Pollination Services for Litchi and Longan Orchards: A Case Study of Huizhou, China

Land-use change has a significant impact on the structure and function of ecosystems and is an important reason for the imbalance between the supply and demand of ecosystem services. Pollination services are indispensable functions of ecosystems. In recent years, land-use change has caused a decline in the abundance of pollinators, thereby affecting the supply of pollination services, which has been a major concern for governments and scholars. Currently, there is an insufficient exploration of the impact mechanism of land-use change on pollination services. The application of a pollination service evaluation model based on land-use data uses a large amount of empirical data, which greatly affects the accuracy of regional evaluation results. This study uses Huizhou as a representative example. Remote sensing images from 2015 and 2019 were used to interpret the land-use data of the region, and the spatiotemporal changes in the land use were then analyzed. Due to their high pollination dependence, litchi and longan were selected as the research objects. Basic data such as the main pollinator species of litchi and longan and floral plant species were obtained through field sampling surveys. The InVEST model was used to evaluate the abundance of pollinators in litchi and longan orchards, and the abundance of pollinators was used to represent the value of pollination services in litchi and longan orchards. Then, the Hotspot analysis method was used to analyze the change in the spatial pattern of the pollinator abundance in litchi and longan orchards. The main influencing factors of pollination service in litchi and longan orchards were analyzed by a Geographical detector. Finally, we have explored the impact mechanism of land-use change on pollination services. The following are the results of this research. The pollinator abundance in the orchards of litchi and longan and their buffer zones in Huizhou decreased by 6.64% and 13.94% from 2015 to 2019, respectively. The wild bee abundance in forest land and rainfed cropland decreased by varying degrees. The spatial aggregation characteristics of pollinator abundance in litchi and longan orchards demonstrated an increase in cold spots, whereas the hot spots decreased and were more dispersed. In the study area, the area change and land-use change of natural or semi-natural habitats, such as forest land, rainfed cropland, and grassland, affected the pollination services for litchi and longan orchards. Within the types of changing land-use, the change of forest land has the greatest impact on litchi and longan pollination services. The impact degrees of Forest land area, rainfed cropland area, area under litchi and longan orchards, and forest landscape fragmentation on the pollination services for litchi and longan orchards were 0.20, 0.16, 0.21, and 0.26, respectively.
Influence of Ingestion of Eicosapentaenoic Acid-Rich Fish Oil on Oxidative Stress at the Menstrual Phase: A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Trial

Background: This study examines the effect of the supplements on the redox reaction in menstrual cycle. Participants took eicosapentaenoic acid (EPA)-rich fish oil supplements over two menstrual cycles. Materials and Methods: For this randomized, double-blind, placebo-controlled trial, 21 female members of a university basketball team were selected. Participants were allocated into the EPA/docosahexaenoic acid (DHA) group (EG, n = 11) and control group (CG, n = 10) through stratified randomization. The EG and CG took 3600 mg fish oil (containing 900 mg EPA and 403 mg DHA) and 3600 mg corn oil (without EPA and DHA), respectively, every day for two menstrual cycles. The redox reaction was measured four times: the menstrual and follicular phases in two menstrual cycles. Results: There was a significant difference in reactive oxygen metabolites (d-ROMs) and potential antioxidant capacity during the menstrual phase by the main effect of time (before and after intake) in EG and CG (p < 0.01). In a subsequent test, d-ROMs were significantly lower after intake in EG and CG (p < 0.05); however, no significant difference in potential antioxidant capacity was found. A significant difference was noted in d-ROMs and potential antioxidant capacity during the follicular phase by the effect of time (before and after intake) only in EG (p < 0.01). Significant decreases in d-ROMs and increases in potential antioxidant capacities were observed after intake (p < 0.05). Conclusion: EPA-rich fish oil supplementation over two menstrual cycles demonstrated active involvement in the antioxidant function during menstrual and follicular phases. The protocol was registered at the University Hospital Medical Information Network Clinical Trial Registry (registration no. UMIN000028795).
How Can Ice Emerge at 0 °C?

The classical nucleation theory shows that bulk water freezing does not occur at temperatures above ≈ −30 °C, and that at higher temperatures ice nucleation requires the presence of some ice-binding surfaces. The temperature and rate of ice nucleation depend on the size and level of complementarity between the atomic structure of these surfaces and various H-bond-rich/depleted crystal planes. In our experiments, the ice nucleation temperature was within a range from −8 °C to −15 °C for buffer and water in plastic test tubes. Upon the addition of ice-initiating substances (i.e., conventional AgI or CuO investigated here), ice appeared in a range from −3 °C to −7 °C, and in the presence of the ice-nucleating bacterium Pseudomonas syringae from −1 °C to −2 °C. The addition of an antifreeze protein inhibited the action of the tested ice-initiating agents.
Types of Lexical Cohesion in Song Lyrics of The Greatest Showman Movie Soundtrack Album

This research aim to finds out types and the most dominant of lexical cohesion used in the song lyrics The Greatest Showman movie soundtrack album. The methodology of this research is descriptive quantitative method. The objects of this research are 5 song lyrics in The Greatest Showman movie soundtrack album namely “A Million Dreams, Never Enough, This Is Me, The Other Side and Rewrite The Stars. The data were collected by using observation sheet and table checklist. The collected data were analyzed by using statistical formula. The result of this research showed that:1. All types of lexical cohesion namely repetition, synonym, superordinate, general words and collocation were found in the song lyrics The Greatest Showman movie soundtrack album. 2. The most dominant type of lexical cohesion is Repetition. It was concluded that repetition occurred dominantly because the composer or writer want to tell the reader and listener that the focus of discourse is in the words which have been repeated to emphasize certain meanings in order to attract attention listeners and to enhance beauty in songs.
Phylotranscriptomics Illuminates the Placement of Whole Genome Duplications and Gene Retention in Ferns

Ferns are the second largest clade of vascular plants with over 10,000 species, yet the generation of genomic resources for the group has lagged behind other major clades of plants. Transcriptomic data have proven to be a powerful tool to assess phylogenetic relationships, using thousands of markers that are largely conserved across the genome, and without the need to sequence entire genomes. We assembled the largest nuclear phylogenetic dataset for ferns to date, including 2884 single-copy nuclear loci from 247 transcriptomes (242 ferns, five outgroups), and investigated phylogenetic relationships across the fern tree, the placement of whole genome duplications (WGDs), and gene retention patterns following WGDs. We generated a well-supported phylogeny of ferns and identified several regions of the fern phylogeny that demonstrate high levels of gene tree–species tree conflict, which largely correspond to areas of the phylogeny that have been difficult to resolve. Using a combination of approaches, we identified 27 WGDs across the phylogeny, including 18 large-scale events (involving more than one sampled taxon) and nine small-scale events (involving only one sampled taxon). Most inferred WGDs occur within single lineages (e.g., orders, families) rather than on the backbone of the phylogeny, although two inferred events are shared by leptosporangiate ferns (excluding Osmundales) and Polypodiales (excluding Lindsaeineae and Saccolomatineae), clades which correspond to the majority of fern diversity. We further examined how retained duplicates following WGDs compared across independent events and found that functions of retained genes were largely convergent, with processes involved in binding, responses to stimuli, and certain organelles over-represented in paralogs while processes involved in transport, organelles derived from endosymbiotic events, and signaling were under-represented. To date, our study is the most comprehensive investigation of the nuclear fern phylogeny, though several avenues for future research remain unexplored.
β2 Integrins on Dendritic Cells Modulate Cytokine Signaling and Inflammation-Associated Gene Expression, and Are Required for Induction of Autoimmune Encephalomyelitis

Heterodimeric β2 integrin surface receptors (CD11a-d/CD18) are specifically expressed by leukocytes that contribute to pathogen uptake, cell migration, immunological synapse formation and cell signaling. In humans, the loss of CD18 expression results in leukocyte adhesion deficiency syndrome (LAD-)1, largely characterized by recurrent severe infections. All available mouse models display the constitutive and ubiquitous knockout of either α or the common β2 (CD18) subunit, which hampers the analysis of the cell type-specific role of β2 integrins in vivo. To overcome this limitation, we generated a CD18 gene floxed mouse strain. Offspring generated from crossing with CD11c-Cre mice displayed the efficient knockdown of β2 integrins, specifically in dendritic cells (DCs). Stimulated β2-integrin-deficient splenic DCs showed enhanced cytokine production and the concomitantly elevated activity of signal transducers and activators of transcription (STAT) 1, 3 and 5, as well as the impaired expression of suppressor of cytokine signaling (SOCS) 2–6 as assessed in bone marrow-derived (BM) DCs. Paradoxically, these BMDCs also showed the attenuated expression of genes involved in inflammatory signaling. In line, in experimental autoimmune encephalomyelitis mice with a conditional DC-specific β2 integrin knockdown presented with a delayed onset and milder course of disease, associated with lower frequencies of T helper cell populations (Th)1/Th17 in the inflamed spinal cord. Altogether, our mouse model may prove to be a valuable tool to study the leukocyte-specific functions of β2 integrins in vivo.
Examining the learning outcomes of elderly through multimedia teaching system in Taiwan

The elderly often fear technology products in Taiwan, because the complexity of technology and the lack of information create barriers for the elderly to use technology. The trends of an aging population and digital product advances mean that new technology products can enrich elderly lives, if learning barriers can be overcome. This study utilises quasi-experimental design and a multimedia teaching system (MTS) as an intervention programme. Seventy-nine older adults (over 65 years old) participated in this study; 39 older adults belonged to the comparison group, and the other 40 were in the experimental group. Subjects' post-test scores were used for evaluating the learning outcome after implementing the intervention programme. The study shows that elderly using MTS improved their learning outcomes significantly more than others who did not. The elderly who received both the MTS and played speed-controlled instruction on their own improved more than those only receiving the MTS. This outcome will benefit those who use technology-based learning among the elderly.
Association of TNF–α rs1800629 with Adult Acute B-Cell Lymphoblastic Leukemia

TNF–α influences lymphomagenesis by upregulating proinflammatory and antiapoptotic pathways. In this study, we evaluated the frequency of TNF–α rs1800629 (–308 G>A) polymorphism in newly diagnosed adult patients with acute lymphoblastic leukemia (ALL) and its correlation with age at diagnosis, gender and subtype of ALL. In this case control study, a total of 330 individuals were recruited, including 165 newly diagnosed adult patients with ALL, from the Radiation and Isotope Center in Khartoum (RICK) and 165 healthy normal controls. TNF–α rs1800629 polymorphism was tested through allele-specific polymerase chain reaction (PCR) assay. The frequency of the rs1800629 GA genotype was high (70.9% vs. 60%, OR = 1.84) in the patient group as compared to healthy controls, whereas GG and AA genotypes did not exhibit any statistically significant difference between controls and patients. Based on subtype, GG and GA rs1800629 genotypes showed increased risk of B-ALL (OR 0.46 and 2.12, respectively), whereas rs1800629 GG, GA and AA genotypes did not show any disease association with T-ALL (p > 0.05). Age at diagnosis and gender did not exhibit any association of rs1800629 with ALL in the patient group. In conclusion, rs1800629 is associated with high risk of adult B-ALL, with an insignificant effect of age at diagnosis and gender.
Umbilical Cord–Derived Stem Cells for the Treatment of Knee Osteoarthritis: A Systematic Review

Background: The use of mesenchymal stem cells (MSCs) for the treatment of knee osteoarthritis (OA) has gained recent interest in the orthopaedics community. Purpose: To review the literature to evaluate the efficacy of umbilical cord–derived MSCs in the treatment of OA of the knee joint. Study Design: Systematic review; Level of evidence, 4. Methods: We searched the PubMed, Cochrane Library, and Embase databases to identify studies with evidence levels from 1 to 4 that evaluated the clinical efficacy of human umbilical cord–derived MSC (hUC-MSC) injections for knee OA. The search phrase used was “umbilical cord knee osteoarthritis. ” In the studies reviewed, patients were assessed based on the macroscopic International Cartilage Regeneration & Joint Preservation Society (ICRS) score, Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC), visual analog scale (VAS) for pain, and the subjective International Knee Documentation Committee (IKDC) score. Results: A total of 7 studies met inclusion criteria, including 385 patients undergoing injection of hUC-MSCs (mean age, 59.7 years). The mean follow-up was 23.4 months. Weighted averages of the WOMAC, macroscopic ICRS, subjective IKDC, and VAS scores all showed improvement from before to after treatment. No severe adverse reactions were recorded. Conclusion: Patients undergoing treatment of knee OA with hUC-MSCs might be expected to experience improvements in clinical outcomes. Additional high-quality randomized studies are needed to better determine the efficacy of hUC-MSC for the treatment of knee OA.