Miracle-dz/UniFAR-FTUs huggingface dataset:
A quantitative and qualitative comparative analysis of collagen fibers to determine the role of connective tissue stroma in oral squamous cell carcinoma using special stains and polarized microscopy

Background: Solid tumors such as oral squamous cell carcinoma (OSCC) are composed of malignant epithelial cells and the stroma in which these cells are dispersed. As the tumor progresses, the extracellular matrix undergoes dramatic morphological and architectural changes. Special stains make analysis easy and less erroneous by highlighting the area of interest and can be used to study these changes. Aim: The aim of the study was to analyze morphological changes in collagen fibers in various histological grades of OSCC using Masson's trichrome (MT) and Picrosirius red (PSR). Study Design: The study comprised 74 tissue samples, divided into two groups: Group I consisted of 63 cases of histologically proven OSCC (39 cases of well-differentiated squamous cell carcinoma [WDSCC], 17 moderately differentiated squamous cell carcinoma [MDSCC] and 7 poorly differentiated squamous cell carcinoma [PDSCC]) and Group II consisted of 11 cases of normal mucosa as controls. Materials and Methods: Sections were stained with hematoxylin and eosin, MT and PSR and observed under light and polarizing microscope, respectively. Statistical Analysis: ANOVA, Tukey's honestly significant difference post hoc multiple comparison test, Chi-square test and paired t-test were used for the statistical analysis. Results: As the grade of OSCC progressed, collagen fibers became thin, loosely packed and haphazard. The mean area fraction also decreased. They exhibited orange–red hue and strong birefringence in WDSCC, yellowish-orange hue and strong birefringence in MDSCC and greenish-yellow hue and weak birefringence in PDSCC. Conclusion: Initially, there is a reorganization of the collagen fibers in an attempt to prevent the invasion of tumor cells, but as cancer progresses, the stromal change enhances movement of the tumor cells within it, leading to metastasis.
Comparing the Effectiveness of Cognitive Behavioral Therapy (CBT) with Acceptance and Commitment Therapy (ACT) in the Enhancement of Marital Satisfaction and Sexual Intimacy in Couples Referred to Counseling Centers

Background: The assessment of young coupleschr('39') marital relationship has received considerable attention in recent years. The present study aimed to make a comparison between the effectiveness of Cognitive Behavioral Therapy (CBT) and Acceptance and Commitment Therapy (ACT) in the enhancement of marital satisfaction and sexual intimacy in couples referred to counseling centers in Khorramabad. Materials and Methods: This quasi-experimental was conducted based on a pre-posttest design with a control group. For the purpose of the study, a total of 60 couples were selected using volunteer sampling out of the entire couples who referred to counseling centers in Khorramabad due to marital disorders in 2018. The couples were randomly assigned to three groups of 20, namely ACT, CBT, and the control group. The data collection tools included the ENRICH marital satisfaction inventory and Battalion sexual intimacy scale. Before the commencement of the intervention (presenting the independent variable), the three groups were provided with the two questionnaires (pre-test). Thereafter, the experimental group received eight two-hour sessions of ACT and eight two-hour sessions of CBT. On the other hand, the control group did not receive any training. Upon the completion of the training sessions, marital satisfaction and sexual intimacy were assessed in the three groups (post-test). Data were analyzed in SPSS software(version 22) using the multivariate analysis of covariance. Results: The obtained results were indicative of the significant effect of both treatments on the enhancement of marital satisfaction (P<0.001) and sexual intimacy (P<0.001) in couples. Moreover, it was found that CBT exerted a more profound effect on marital satisfaction and sexual intimacy, compared to ACT. Conclusion: As evidenced by the obtained results, it can be concluded that both CBT and ACT were effective in the promotion of marital satisfaction and sexual intimacy in couples. Nonetheless, CBT demonstrated more dramatic effects, compared to ACT.
COVID-19's disruption of India's transformed food supply chains

COVID-19 has created high transaction costs and uncertainty in India's transformed food supply chains, putting food security at risk as 92% of food consumption in India is purchased, predominantly from the private sector Government faces the challenge of marshalling resources between mitigating the impending food crisis and containing the contagion as the risk of sociopolitical tensions looms large It is recommended that the government concentrate on sustaining the food supply chains towards eventual rebound, recognising that government food distribution cannot replace even a tenth of the market
Executive stock options and systemic risk

We examine whether features of bank executives’ compensation contracts cause them to take actions that contribute to systemic risk. Using multiple return-based measures of systemic risk coupled with an identification strategy that exploits heteroskedasticity to account for endogenous matching of executives and banks, we find that bank executives’ equity portfolio vega leads to greater subsequent systemic risk that manifests during economic downturns, but not during expansions. We also find that vega encourages bank executives to pursue specific activities that contribute to the accretion of systemic risk, including: (i) maintaining lower Tier 1 capital ratios, (ii) investing in commercial and industrial loans, which tend to track the business cycle, and non agency mortgagebacked securities, which are subject to greater default and liquidity risk, and (iii) greater reliance on liabilities subject to runs (i.e., short-term deposits). Collectively, our evidence suggests that bank executives’ incentive-compensation contracts promote systemic risk-taking by encouraging them to adopt lending, investment, and financing policies that are highly procyclical and contagious.
Mesoscale cortical calcium imaging reveals widespread synchronized infraslow activity during social touch in mice

We employ cortical mesoscale GCaMP6s imaging of intracellular calcium levels to establish how brain activity is correlated when two mice engage in a staged social touch-like interaction. Using a rail system, two head-fixed mice begin at a distance where social touch is not possible (160 mm), after 90s they are brought so that macrovibrissae contact each other (6-12 mm snout to snout) for an additional 135s. During the period before, during, and after contact cortical mesoscale GCAMP6 signals were recorded from both mice simultaneously. When the mice were together we observed bouts of mutual whisking resulting in cross-mouse correlated barrel cortex activity. While correlations between whisker cortices were expected given mutual whisking, we also found significant synchronized brain-wide calcium signals at a frequency band of 0.01-0.1Hz when the mice were together. We present dual mouse brain imaging as new paradigm to assess social interactions in a more constrained manner. The effects of social interaction extend outside of regions associated with mutual touch and have global synchronizing effects on cortical activity.
Epidemiological Characteristics of Major Depression of Hospitalized Patients in Psychiatric Hospital “Demir Hisar” – Demir Hisar for a Five Year Period from 2013 to 2017

BACKGROUND: Severe depression is a mental disorder with a wide range of changes in psychic functions, primarily of affectivity, and is manifested by dysphoric mood and reductive changes in cognitive, conative, and other psychic dynamics, with the presence of psychosomatic complaints and suicidal thoughts. There is always a triad of symptoms: Alteration of affectivity, anhedonia, and low energy with fatigue, but in her clinical picture, there are other symptoms, such as feeling guilty and helpless, obsessed with “black thoughts” with loss of confidence in themselves, with hopelessness, loss of appetite, and weight loss with present insomnia or hypersomnia, and more frequent thinking about death due to the feeling of worthlessness of life. This mental illness covers a vast area of the affective life of a human with a broad spectrum classified by ICD - 10- F 32, F 32.2, and F 32.3. AIM: The main goal is to determine the total number of patients with the major depression treated at “Demir Hisar” Psychiatric Hospital for a period of 5 years, retrospectively in 2013 until 2017 and to determine the impact of socio-demographic variables as risk factors and predictors. METHODS: The study is retrospective, and the necessary parameters for achieving the goals of the research are provided by analyzing the medical histories of all hospitalized patients treated in psychiatric hospitals Demir Hisar in the period from 2013 to 2017. Incidence rates and indexes of the dynamics of hospitalized patients with major depression were determined. RESULTS: About 61.8% of the patients are men and 38.2% women. Patients with no education and elementary school were 64.5% versus patients with high school and university 35.5% and are significantly underpowered. Regarding the employment status, 38.2% of patients are unemployed, and 61.8% of patients are employed. According to the cross-sectional study, 64.7% of men without education have severe depression and live in the city, and 53.3% of women with secondary education live in urban areas (city), meaning rural residence is associated with a reduced rate of severe depression. CONCLUSION: We can conclude that socio-demographic characteristics – age, gender, marital status, level of education, employment/unemployment status, and place of residence are related to the severity of depression.
Maladaptive Shifts in Life History in a Changing Environment*

Many species facing climate change have complex life cycles, with individuals in different stages differing in their sensitivity to a changing climate and their contribution to population growth. We use a quantitative genetics model to predict the dynamics of adaptation in a stage-structured population confronted with a steadily changing environment. Our model assumes that different optimal phenotypic values maximize different fitness components, consistent with many empirical observations. In a constant environment, the population evolves toward an equilibrium phenotype, which represents the best compromise given the trade-off between vital rates. In a changing environment, however, the mean phenotype in the population will lag behind this optimal compromise. We show that this lag may result in a shift along the trade-off between vital rates, with negative consequences for some fitness components but, less intuitively, improvements in some others. Complex eco-evolutionary dynamics can emerge in our model due to feedbacks between population demography and adaptation. Because of such feedback loops, selection may favor further shifts in life history in the same direction as those caused by maladaptive lags. These shifts in life history could be wrongly interpreted as adaptations to the new environment, while in reality they only reflect the inability of the population to adapt fast enough.
Efficacité biopesticide de Hyptis spicigera Lam., Azadirachta indica A. Juss. et Euphorbia balsamifera Ait. sur le niébé Vigna unguculata L. Walp

Le test biopesticide de trois espèces végétales (Hyptis spicigera Lam., Azadirachta indica A. Juss. et Euphorbia balsamifera Ait.) a révélé que l’efficacité de ces produits sur les parasites du niébé n’était pas meilleure à la deltaméthrine. Les parcelles traitées avec ces extraits botaniques ont produit plus de fanes que de grains. Des recherches plus approfondies sont nécessaires pour caractériser ces substances et éventuellement améliorer leur efficacité pesticide. Efficacité biopesticide de Hyptis spicigera Lam. , Azadirachta indica A. Juss. et Euphorbia balsamifera Ait. sur le niébé Vigna unguculata L. Walp.
Stabilization of the Soliton Transported Bio-energy in Protein Molecules in the Improved Model

We study the stabilization of the soliton transported bio-energy by the dynamic equations in the improved Davydov theory from four aspects containing the feature of free motion and states of the soliton at the long-time motion and at biological temperature 300 K and behaviors of collision of the solitons by Range-Kutta method and physical parameter values appropriate to the ~-helix protein molecules. We prove that the new solitons can move without dispersion at a constant speed retaining its shape and energy in free and long-time motious and can go through each other without scattering. If considering further influence of the temperature effect of heat bath on the soliton, it is still thermally stable at biological temperature 300 K and in a time as long as 300 ps and amino acid spacings as large as 400, which shows that the lifetime of the new soliton is at least 300 ps, which is consistent with analytic result obtained by quantum perturbation theory. These result, s exhibit that the new soliton is a possible carrier of bio-energy transport and the improved model is possibly a candidate for the mechanism of this transport.
Effect of Carob (Ceratonia siliqua L.) oral supplementation on changes of semen parameters, oxidative stress, inﬂammatory biomarkers and reproductive hormones in infertile men

Background and Aim: Reduction in sperm motility is one of the main causes of male infertility. The aim of this study was to investigate the effect of Carob supplementation on sperm parameters, inflammatory factors, oxidative stress indices and sex hormones in the men with idiopathic infertility. Materials and Methods: This study was a randomized double-blind controlled clinical trial which included 60 men with asthenospermia. The patients were assigned to intervention and placebo groups (n =30). The intervention group received 1500 mg Carob / day (three 500 mg capsules), and the placebo group received three placebo capsules / day for 12 weeks. The parameters of sperm, total antioxidant capacity, malondialdehyde concentration, inflammatory markers and plasma sex hormones were measured at the beginning and at the end of the study. Statistical analysis was performed by SPSS software and independent sample t-test was used to compare the mean values of changes between the two groups. P-value of less than 0.05 was considered statistically significant. Results: Differences in the changes in number, concentration and the percentage of motile sperms, total antioxidant capacity, concentration of MDA and plasma inflammatory markers were significant after the intervention (p<0.05). Changes in sex hormones were not significant in the two groups (P>0.05). Conclusion: Increased concentration and motility of the sperm and decreased oxidative stress and inflammatory factors were observed in the intervention group. Use of plants with antioxidant capacity can be one of the ways to cope with oxidative damage to sperm in this group of infertile men.
IS THE EFFICIENCY OF BANKS DEGENERATING DUE TO THE MOUNTING OF NON-PERFORMING ASSETS? AN EMPIRICAL INVESTIGATION USING DEA

Indian banking system is saddled with bad loans which have resulted in huge losses. Profitability remains a concern due to the rise of NPAs. Investors should not expect high reporting profits from banks due to the ascending provision of the NPAs. Banks are not performing well and they may not be much efficient due to the rise of NPAs daily. Using data envelopment analysis, the present study intends to assess technical efficiency of banks. As the requirement of homogeneity is fulfilled, the input oriented CCR model is applied. The study finds that the number of efficient banks has shortened and the average overall technical efficiency of selected banks moves downward throughout the study period. It also reveals that the inefficiency is mostly due to the upward trend of NPAs. Asset quality plays the most crucial role toward the performance of banking sector. Thus, banks and regulators should control the upward trend of NPAs to enhance the efficiency level.
Le condizioni organizzative e professionali dello smart working dopo l'emergenza: progettare il lavoro ubiquo fatto di ruoli aperti e di professioni a larga banda

The Covid-19 lockdown generated an unprecedented experiment: extensive ubiquitous work (or smart working, home working, remote working, WFH-Working from Home, agile work, teleworking) involving almost 8 million people. This way of working has been well known for more than twenty years, but with limited pilot experiences. After the emergency, ubiquitous work may be consolidated and spreaded out only if it is designed and managed with rigor, method and appropriateness to different contexts, choosing the right proportion between on-site work and remote work. Action should be taken on rules, supporting technologies, way of managing work and life, mindset, but above all on the conception of offices and their organization and work, also inspired by success stories developed in these years. Ubiquitous work and blended offices between the physical and the virtual can work well under three socio-organizational conditions: a) going beyond the concept of the office-factory; b) favor organizations based on sociotechnical systems oriented towards measurable economic and social objectives and on 4C model (self-regulated cooperation, knowledge sharing, extended communication, performing community); c) redesigning the work based upon roles and professions, overcoming tasks, positions and levels. Our proposals concern first the methods and models for designing and managin smart working/ubiquitous work and second the launch of: a) a large multidisciplinary research program on the "smart working experiment" tooking place during and immediately after lockdown, a program to be conducted collaboratively by Italian research centers and universities, in strong relationship with Europe; b) a support program for SMEs and the Public Administration offered by universities, IT companies, consultancy, training, interior design with sustainable methods and costs. The recipients of the first proposal are companies and public administrations and their stakeholders; the recipients of the second proposal are the world of research and the world of public policies based upon pacts agreements among institutions and intermediate bodies like employers and workers agencies, education systems, media and the others .
Evaluation Numerical Methods Effectiveness for Processing of Measurement Results by Improved SPR-Sensor

In this work there has been investigated the effect of electron beam treatment of the glass substrates surface of sensors based on surface plasmon resonance phenomenon with active gold based layer on the accuracy of determining the angular position of the reflection characteristics in case applying numerical methods for processing direct measurement results: approximation by polynomials of the 2nd 3rd and 4th degrees and processing by midline method. Sensors with different specific powers of electron beam treatment of glass substrates were investigated: 0, 27, and 36 W/mm2. The reflection characteristics for the gold-air interface were investigated. According to the results of experiments and numerical analysis, it was found that the effect of electron beam treatment on the change in the absolute error in determining the minimum reflection characteristics substantially depends on the chosen numerical method. Thus, the improved midline method provides a 6-fold decrease in the absolute measurement error compared to the midline method for samples without processing and almost 12 times for samples with processing power of 27 W/mm2. Moreover, for this method, the smallest absolute error is observed for the power of electron beam treatment 36 W/mm2 and is 0,58 arc sec. , which indicates the appropriateness of applying new method. Compared to the approximation methods by polynomials and the midline method, the improved midline method has greater accuracy in determining the minimum reflection characteristics because it depends less on not only its symmetry associated with the optical characteristics of the gold-air transition layer, but also on changes in the intensity of reflected light minimum reflection characteristics. According to the results of calculations based on predefined optical constants from the measured reflection characteristics, it was found that, with a higher irradiation power, the symmetry of the reflection characteristic, the propagation distance and the penetration depth of surface plasmons increase, which is associated with a decrease in surface roughness after electron beam treatment and, as a consequence, a decrease in attenuation fields of surface plasmons. Research can be useful in the development of sensors based on surface plasmon resonance phenomenon and methods for processing measurement results
THE INFLUENCE OF BOARD OF DIRECTORS’ CHARACTERISTICS ON THE ENVIRONMENTAL DISCLOSURE AMONG MALAYSIAN COMPANIES

The environmental activities conducted by companies have been scrutinised by the public due to the huge environmental problems faced by many people across the world. These activities are corporate social activities included in the corporate social responsibility (CSR) framework by Bursa Malaysia that informs the public regarding the social and environmental activities implemented by Malaysian companies. Data from 353 companies of various types in Malaysia revealed that the information about effective usage of energy and resources is the most disclosed item by Malaysian companies, followed by the waste management and disposal, and reusing and recycling information. The least disclosed item by Malaysian companies is prevention and reparation program. In addition, the regression results showed that the higher proportion of non-executive directors could increase the disclosure of environmental information. The results prove that the non-executive directors have played their role to increase the companies’ legitimacy by encouraging the management of companies to provide more environmental information. Hence, this study provides significant contribution for the supervisory bodies and policy makers in developing guidelines for Malaysian companies concerning environmental issues through environmental disclosures in their annual reports.
THE EFFECT OF COMMUNICATION ON EMPLOYEE PERFORMANCE AT CENTER OFFICE OF HASANUDDIN UNIVERSITY WITH MOTIVATION AS INTERVENING VARIABLES

National education institutions should be able to compete in this globalization era. This study aims to determine the effect of communication on performance with motivation as an intervening variable at the Center Office of Hasanuddin University. This research is a quantitative descriptive using primary data in the form of a questionnaire. The population in this study were 214, of the population taken by using the Slovin technique of 139 people with random sampling. Data were analyzed using path analysis with SPSS version 25. Structural equation test results show that all variables have a positive or direct effect because all beta values ​​are positive. The results of partial testing (T-test) showed that all the variables had a significant effect because all variables had t-counts greater than t-table. Simultaneous test results (F test) found that communication, motivation, and discipline simultaneously influence (simultaneously) on employee performance because the value of F-count is greater than F-table. The conclusion from this study is that the variables of communication and motivation have a positive and significant effect on employee performance.