Miracle-dz/UniFAR-FTUs huggingface dataset:
An overview of SARS-COV-2-related hepatic injury

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative pathogen of coronavirus disease 2019 (COVID-19), is highly contagious and has a variety of clinical manifestations, including liver injury. There have been a few reports indicating acute-on chronic liver failure among COVID-19 patients, however, patients with COVID-19-related liver injury are generally asymptomatic and present with a mild to moderate elevation in serum hepatic enzymes. Severe COVID-19 patients have high rates of liver injury with poorer outcomes. The pattern of abnormalities in liver biochemical indicators may be hepatocellular, cholestatic, or mixed. Although the pathogenesis of hepatic injury is not yet completely understood, causes of liver damage include systemic inflammatory response syndrome, ischemia-reperfusion injury, side effects of medications, and underlying chronic liver disease. While viral RNA has been detected in hepatocytes, it remains unknown if the coronavirus has the capacity to cause cytopathic effects in hepatic tissue. Additionally, it is important to remember that the current upheaval to daily life and access to healthcare caused by the COVID-19 pandemic has had a significant and negative effect on other patients with chronic liver disease. The objective of this review was to summarize the current literature on COVID-19-related hepatic injury with an examination of clinical features, potential pathogenesis, and histopathological findings of this entity.
Melatonin and Sleep Disturbances in Children With Atopic Dermatitis

Objective To evaluate the correlation between melatonin levels and sleep quality, based on the Children’s Sleep Habit Questionnaire (CSHQ), among children with atopic dermatitis (AD). Methods This was an analytic study with a cross-sectional design involving two groups, AD children as the case group and participants without AD as the control group, conducted at the Pediatric Dermatology Clinic of Dr. Hasan Sadikin Hospital, Bandung, Indonesia. Melatonin levels and CSHQ score in the case group were compared to that in the control group. Correlation analysis was performed between melatonin levels and sleep quality based on CSHQ in the case group. Results Participants in this study consisted of 19 children with moderate AD, (no patient with mild and severe AD was recruited), and 19 participants without AD. The mean CSHQ score in the case group was significantly higher than the control group (47.84 vs 36.79; p<0.05). The mean melatonin level in the case group was significantly lower than the control group (320.18 pg/mL vs 383.86 pg/mL; p<0.05). Comparative analysis was conducted using independent t-test. There was a significant Pearson’s correlation index between SCORAD and CSHQ (p<0.05). However, there was no correlation between melatonin levels and CSHQ, as well as between melatonin levels and SCORAD (p<0.05). Conclusion Children with moderate AD have impaired sleep quality and lower melatonin levels compared to controls. No correlation was found between melatonin levels and CSHQ, as well as melatonin levels and SCORAD, although there was a strong and significant correlation between SCORAD and CSHQ. Therefore, melatonin levels may not be the main cause of sleep disturbances in children with moderate AD.
Influence of Technological Strategies on Performance of Standard Gauge Railway in Kenya

ix CHAPTER ONE: INTRODUCTION . 1 1.1 Background to the Study . 1 1.1.1 Technological Strategies . 3 1.1.2 Performance of Organization in Kenya . 5 1.1.3 Railway Transport in Kenya . 6 1.1.4 Standard Gauge Railway Project in Kenya . 7 1.2 Research Problem . 8 1.3 Research Objectives . 10 1.4 Value of the Study . 10 CHAPTER TWO: LITERATURE REVIEW . 12 2.
Expression of Cyclooxygenase-2 and Granulocyte-Macrophage Colony-Stimulating Factor in the Endometrial Epithelium of the Cow Is Up-Regulated During Early Pregnancy and in Response to Intrauterine Infusions of Interferon-t1

On the basis of results obtained in vitro, we previously proposed a model in which signals from the conceptus, namely interferon-tau (IFN-t) and prostaglandin E2, increase the expression of cyclooxygenase (COX)-2 or granulocyte-macrophage colony-stimulating factor (GM-CSF) in immune and nonimmune cells of the bovine endometrium. Two experiments were conducted to verify the validity of this hypothesis in vivo. In experiment 1, the in vivo expression of COX-2 and GM-CSF during early pregnancy was monitored. Uteri from heifers were collected at different days (d) of the estrous cycle and pregnancy (P). In experiment 2, the effects of intrauterine infusions of IFNt on the expression of COX-2 and GM-CSF were analyzed. Immunohistochemistry was performed on uterine sections, and image analysis was used to evaluate the staining intensity in the conceptus, the luminal epithelium (LE), and the subepithelial stroma. In experiment 1, staining for COX-2 was maximal between d18P and d24P, both in the LE and in the conceptus, whereas staining for GM-CSF reached a plateau between d18P and d30P in the LE. In experiment 2, in response to IFN-t, COX2 was up-regulated in the LE of the ipsilateral horn, whereas GM-CSF was enhanced in both uterine horns. The current report supports the view that the conceptus, through its secretion of IFN-t, stimulates maternal epithelial expression of COX-2 and GM-CSF during the peri-attachment period in the cow. conceptus, female reproductive tract, growth factors, pregnancy, uterus
Job satisfaction and organisational commitment: An Empirical Evidence in Small and Medium Size Enterprises in Cameroon.

The main purpose of this study was to investigate the influence of job satisfaction on the commitment of employees of small and medium size enterprises (SMEs) in Cameroon for their organisations. General job satisfaction was used as dependent variable then the three foci of commitment were used as dependent variables. Three hypotheses were formulated based on the link of the concepts in literature. The data for the study was collected using questionnaire on a sample size of 1556 employees of SMEs in Cameroo n. The data was analysed using Pearson correlation analyses and regression analyses. The result reveals that job satisfaction has a positive and significant influence on the affective, normative and continuance commitment of employees of SMEs for their organisations. From this result it was recommended that the management of SMEs in Cameroon should always bring up strategies to keep their employees satisfied to their jobs so as to be committed.
Biochemical Markers for Alzheimer’s and Parkinson’s Disease

Many biomarkers are currently being searched in neurodegenerative diseases like Alzheimer’s disease and Parkinson’s disease. These diseases share some common pathophysiological mechanisms and the presence of protein aggregates. Measurements of those proteins -like tau, amyloid-beta peptide and α-synuclein-, as well other mediators of neurodegeneration in cerebrospinal fluid and peripheral fluids have been explored as biomarkers. Here we summarize some of the available data on biochemical markers for neurodegenerative diseases, considering advantages and drawbacks of each marker and method of analysis.
Finding the Number of Cubes in Rectangular Cube Buildings.

by the National Council of Teachers of Mathematics, Inc. www.nctm. org. All rights reserved. NCTM is not responsible for the accuracy or quality of the translation ____________________________________________________________________ ____ ידוסיה ךוניחב הקיטמתמל יצרא םירומ זכרמ il . ac . haifa . 6 k mathcenter :// http 1 םיינבלמ תויבוק ינבמב תויבוקה רפסמ תאיצמ Finding the Number of Cubes in Rectangular Cube Buildings
CLINICAL MANIFESTATIONS OF HYPOTHYROIDISM IN RESIDENTS OF RAWALPINDI

the the ABSTRACT Background: This study was designed for the evaluation of the difference in the common signs and symptoms of hypothyroidism in our population from already available literature. Methods: In this study we have compared the symptoms and signs of hypothyroid and euthyroid patients visiting to Holy Family Hospital from April 2017 to October 2017. We compared the 18 common signs and symptoms of hypothyroidism in our patients and analyzed by SPSS software. Results: Of the 2483 patients visiting to the HOSPITAL, 665 patients were included in the study and were examined. After the laboratory investigations, 98 were identified as the cases of hypothyroidism, the rest were declared as euthyroid and selected as controls. Lethargy, cold intolerance, constipation and paresthesia were the commonest symptom while facial oedema and bradycardia were the most prevalent sign in our population. Conclusions: The most common signs and symptoms of hypothyroidism in Pakistan (that is one of the iodine deficient areas in Pakistan) were different from other studies. It seems that strong clinical suspicion on the basis of symptoms and signs elicited by physicians and laboratory confirmation are the only reliable methods for diagnosis of hypothyroidism. significantly among different populations owing to their climate, education status and awareness about the disease.
Nitrogen Metabolism in the Stalk Tissue of Maize

During ear development in maize (Zea mays L.), nitrogenous compounds are translocated from vegetative organs to the ker-nels. At anthesis, the stalk contains approximately 40% of the total plant N, and contributes 45% of the N remobilized to the ear. Therefore, the stalk has an important function as a temporary reservoir for N. Little is known of the metabolism of maize stalks, and this paper describes initial studies of enzymes of N metabolism. High in vitro activity of glutamine synthetase (GS) in maize stalk samples throughout ear development contrasted with a peak in activity of glutamate synthase soon after anthesis and negligible nitrate reductase. With fresh sections of stalk tissue collected at anthesis, '5N-feeding experiments confirmed high GS and low nitrate reductase activities. Two isoforms of GS were separated from extracts from stalk tissue: GS1, the cytoplasmic form, increased to maximum levels at 2 weeks postanthesis and remained fairly high thereafter; whereas the plastidic form, GS2, declined progressively during kemel development. Westem blot analysis confirmed the presence of constantly high levels of GS protein after anthesis. The levels of GS proteins decreased after transfer of N-starved, hydroponically grown plants to N-rich con- ditions in order to restrict remobilization of N. In contrast, transfer of plants grown under abundant N conditions to N-free medium, which encourages N remobilization, resulted in a relative increase in GS protein. Because glutamine is the major form of N trans-ported in maize, the results indicate that GS, specifically the GS1 isoform, has a central role in the remobilization on nitrogenous compounds from the stalk to the ear.
Title:Seeing yourself clearly: Self-identification of a body image problem in adolescents with an eating disorder Running title: Self-identification for eating disorders

1 Centre for Emotional Health, Department of Psychology, Macquarie University, Sydney, Australia 2 Department of Psychiatry, Columbia University, New York, NY, United States of America 3 Centre for Rural Health, University of Tasmania, Launceston, Australia 4 Melbourne School of Psychological Sciences, University of Melbourne, Melbourne, Australia 5 Department of Psychiatry, University of California San Francisco, San Francisco, CA, United States of America 6 Translational Health Research Institute, School of Medicine, Western Sydney University, Sydney, Australia 7 School of Medicine, Western Sydney University, Sydney, Australia
A Time-Scale Decomposition Approach to Statistically Downscale Summer Rainfall over North China

A time-scale decomposition (TSD) approachto statistically downscalesummer rainfallover North China is described. It makes use of two distinct downscaling models respectively corresponding to the interannual and interdecadal rainfall variability. The two models were developed based on objective downscaling scheme that 1) identiﬁes potential predictors based on correlation analysis between rainfall and considered climatic variables over the global scale and 2) selects the ‘‘optimal’’ predictors from the identiﬁed potential predictors via cross-validation-based stepwise regression. The downscaling model for the interannual rainfall variability is linked to El Nin˜o–Southern Oscillation and the 850-hPameridionalwind over East China, while theone for the interdecadal rainfall variability is related to the sea level pressure over the southwest Indian Ocean. Taking the downscaled interannual and interdecadal components together the downscaled total rainfall was obtained. The results show that the TSD approach achieved a good skill to predict the observed rainfall with the correlation coefﬁcient of 0.82 in the independent validation period. The authors further apply the model to obtain downscaled rainfall projections from three climate models under present climate and the A1B emission scenario in future. The resulting downscaled values provide a closer representation of the obser- vation than the raw climate model simulations in the present climate; for the near future, climate models simulated a slight decrease in rainfall, while the downscaled values tend to be slightly higher than the present state.
Linear Approximations for the Influence of Phasor Angle Difference Errors on Line Parameter Calculation

Phase angle measurements from phasor measurement units (PMUs) may have errors that can significantly affect line parameter calculation. In this paper, approximate expressions for the influence of phase angle difference errors on line parameter calculation are derived. Specifically, first the PMU phase angle error at both ends of a line is analyzed and an equivalent synchronization error is defined; second, approximated expressions for the influence of current and voltage phase angle difference error on the line parameters are derived. The voltage amplitude ratio on the relative error of line reactance, resistance, and capacitance measurement through the π-type equivalent model are considered. The influence of voltage and current phase angle difference error on reactance and resistance is shown from the perspective of relative sensitivity. The relative sensitivity expressions in active power form are given and the identifiable conditions of line reactance parameters based on PMU data are given. In addition, this paper presents the influence mechanism of voltage magnitude and discusses the case of synchronization issue. Finally, the accuracy of the sensitivity equations is verified by simulations, and the influence of the voltage amplitude ratio and the line flow on the identification result is quantitatively analyzed.
Bioactive Compounds from Cereal and Pulse Processing Byproducts and Their Potential Health Benefits

An enormous amount of byproducts (bran, husk, germ meal etc.) is generated worldwide during the processing of cereals and pulses, which are a rich source of bioactive compounds. The major components include phenolic acids (ferulic, gentisic, p-hydroxybenzoic, gallic, sinapic, syringic, vanillic, caffeic, p-coumaric), dietary fibers (β-glucan), vitamins (thiamin, riboflavin, niacin, pantothenic acid) etc. These bioactive components are associated with various health benefits such as anti-inflammatory, antioxidant and anti-diabetic, anti-carcinogenic etc as well as modulation of the metabolic processes. This review provides comprehensive information about different types of bioactive compounds present in the byproducts produced from cereal and pulse processing industries and their health benefits.
DMSO_A_287459 5071..5078

Department of Internal Medicine, Faculty of Medicine, Rabigh, King Abdulaziz University, Jeddah, Saudi Arabia Purpose: This study aimed to investigate knowledge, attitudes, and practices regarding diabetes mellitus (DM) among university students. Material and Methods: This cross-sectional study was carried out at the Faculty of Medicine, Rabigh, King Abdulaziz University (KAU) Jeddah, Kingdom of Saudi Arabia (KSA), in 2018. All participants were the registered students at the foundation year in the branch of KAU, Rabigh. A questionnaire was developed that had questions related to knowledge, attitudes, and practices. Results: A total of 1428 participants (770 [53.9%] females and 658 [46.1%] males) were included in the study. Surprisingly, there were 315 (22.1%) students who had been diagnosed with hypertension or told by the healthcare professional that he/she has increased blood pressure, and 223 (15.6%) had high blood sugar. There were 785 (55%) participants who had one or more DM relative. Among our students, only 186 (13%) had good knowledge scores, while 569 (39.8%) and 673 (47.1%) had moderate and poor knowledge scores, respectively. Interestingly, 1190 (83.3%) participants had positive attitudes, while 238 (16.7%) had negative attitudes. More than half of the participants, 844 (59.1%), were practicing adequately for preventing DM. It was observed that females had significantly better general knowledge about DM, its risk factors, signs and symptoms, control and management, complications, and total knowledge scores. Our results showed that the female gender was associated with good knowledge and positive attitude and relatives diagnosed with DM were associated with good knowledge score. The participants who had DM relative and hypertension were more likely to have good attitudes and practices, respectively, in preventing DM. Conclusion: Our students’ knowledge score was not up to the mark. Interestingly, participants had positive attitudes and practicing adequately for preventing DM. The female gender was associated with good knowledge scores and positive attitudes.
Who will lead and who will follow: Identifying Inﬂuential Users in Online Social Networks A Critical Review and Future Research Directions

One of the most important questions at the heart of viral marketing is how companies can identify and target the “right” initial set of inﬂuential users in Online Social Networks (OSN). Even though we ﬁnd that both the scientiﬁc Business and Information Systems Engineering (BISE) and Marketing community engage in research on the identiﬁcation of inﬂuential users in OSN, the development of practical approaches is still in its infancy. Therefore, we analyze and synthesize the growing number of scientiﬁc publications and hope that the results can stimulate and guide future research. LT model by weighting edges that account for similarity between users . Solve the problem by applying centrality, greedy , and combined algorithms . Apply their approach to an Epinion data set and show that the graph built by “trust” and “review-rate” includes more information on the social network. Thus, a degree centrality-based algorithm often performs even better than the general and hill-climbing greedy algorithm. Examine the inﬂuence maximization problem ( top-k nodes problem ) using a SIR model (namely IC ) in an undirected graph . Adapt the IC model by weighting edges that account users’ preferences for speciﬁc topics . Solve the problem under an optimized greedy algorithm including Monte Carlo simulation . Experimental results show that the approach signiﬁcantly outperforms the traditional greedy algorithm in terms of information diffusion on speciﬁc topics . Information Systems Engineering (BISE) and Marketing communities could be mutually beneﬁcial. With respect to a practitioner’sperspective,theycompileadviceonthepracticalapplicationofapproachesfortheidentiﬁcationofin-ﬂuentialusers. Itishopedthatthere-sults can stimulate and guide future research.
Using Reaggregated Thymic Organ Cultures Tolerance and Regulatory T Cell Generation Analysis of APC Types Involved in CD4

Tolerance to self-Ags is generated in the thymus. Both epithelial and hematopoietic thymic stromal cells play an active and essential role in this process. However, the role of each of the various stromal cell types remains unresolved. To our knowledge, we describe the ﬁrst comparative analysis of several types of thymic hematopoietic stromal cells (THSCs) for their ability to induce CD4 tolerance to self, in parallel with the thymic epithelium. The THSCs—two types of conventional dendritic cells (cDCs), plasmacytoid dendritic cells, macrophages (M F s), B lymphocytes, and eosinophils—were ﬁrst characterized and quantiﬁed in adult mouse thymus. They were then examined in reaggregated thymic organ cultures containing mixtures of monoclonal and polyclonal thymocytes. This thymocyte mixture allows for the analysis of Ag-speciﬁc events while avoiding the extreme skewing frequently seen in purely monoclonal systems. Our data indicate that thymic epithelium alone is capable of promoting self-tolerance by eliminating autoreactive CD4 single-positive thymocytes and by supporting regulatory T cell (Treg) development. We also show that both non-Treg CD4 single-positive thymocytes and Tregs are efﬁciently deleted by the two populations of cDCs present in the thymus, as well as to a lesser extent by M F s. Plasmacytoid dendritic cells, B lymphocytes, and eosinophils were not able to do so. Finally, cDCs were also the most efﬁcient THSCs at supporting Treg development in the thymus, suggesting that although they may share some characteristics required for negative selection with M F s, they do not share those required for the support of Treg development, making cDCs
A New Steganography Algorithm for Image Hiding using Gödelization Under Frequency Domain

: Steganography, known as the art of hiding information, is a means of embedding data within another data while protecting its secrecy. The proposed method in this paper focuses on hiding the data(image) under frequency domain making use of Modulation technique, which embeds the secret data in the DCT domain of the cover image to increase the robustness of the scheme against JPEG compression. To enhance the security, the secret data is encoded using a technique called Gödelization and compressed using Alphabetic Coding techniques. The encoded compressed data which is obtained is embedded into the DCT domain of the cover image. The proposed methodology is proved to be secure and is resistant to JPEG attacks.
TOLERANCE TO ABIOTIC STRESS CONDITIONS BY PROMOTING

THE LSM1-7 COMPLEX DIFFERENTIALLY REGULATES ARABIDOPSIS 1 TOLERANCE TO ABIOTIC STRESS CONDITIONS BY PROMOTING 2 SELECTIVE mRNA DECAPPING 3 4 5 Carlos Perea-Resa1*, Cristian Carrasco-López1*, Rafael Catalá1, Veronika 6 Turečková, Ondrej Novak, Weiping Zhang, Leslie Sieburth, José Manuel 7 Jiménez-Gómez4,5 and Julio Salinas1,† 8 9 Departamento de Biología Medioambiental, Centro Investigaciones Biológicas, CSIC, 1