Miracle-dz/UniFAR-FTUs huggingface dataset:
Signiﬁcance of right bundle branch block in the diagnosis of myocardial ischemia in patients undergoing coronary artery bypass grafting

Background : Perioperative diagnosis of myocardial ischemia following cardiac surgical procedures remains a challenging problem. Particularly, the role of new conduction disturbances as markers of postoperative ischemia is still questionable. The goal of this study was to elucidate the diagnostic signiﬁcance of new postoperative right bundle branch block (RBBB) for the detection of perioperative myocardial ischemia in patients undergoing elective coronary artery bypass grafting (CABG). Methods : In 169 consecutive patients, three-channel Holter monitoring and serial assessment of serum enzymes were performed for 48 h, and 12-lead ECG repeated for up to 5 days post-operatively. Postoperative events were classiﬁed as either myocardial infarction (MI), transient ischemic events (TIE) or various conduction disturbances. Results : Transient ( n (cid:136) 9) or permanent ( n (cid:136) 4) RBBB occurred in 13 patients (8%); 14 patients (8%) showed signs of perioperative MI and 18 patients (11%) evidence of TIE. Peak activity of creatine-kinase (CK, 561 ^ 135 vs. 316 ^ 19, P , 0 : 05) and CK-MB (22.7 ^ 3.2 vs. 13.4 ^ 0.8, P , 0 : 01) were higher in patients with RBBB than in patients without perioperative ischemic events. Peak CK-MB levels were signiﬁcantly higher in patients with MI as compared to those with RBBB (33.4 ^ 7.6 vs. 22.7 ^ 3.2, P , 0 : 05). Patients with TIE had similar perioperative enzyme levels as patients with no events. Conclusion : It is concluded that the combined assessment of repeated 12-lead ECG, continuous Holter monitoring and enzyme analysis allows a reliable diagnosis of perioperative myocardial ischemia and conduction disturbances. The occurrence of new RBBB following elective CABG is indicative of perioperative myocardial necrosis and thus serves as a valuable tool for the diagnosis of new, perioperative ischemic events. q 2000 Elsevier Science B.V. All rights reserved. Right
Large crown root number improves topsoil foraging and phosphorus 7 acquisition 8

Summary : Maize genotypes with more crown roots have more intensive topsoil foraging 14 and superior phosphorus acquisition, growth, and yield in low phosphorus soil. Abstract 27 Suboptimal phosphorus availability is a primary constraint to plant growth on 28 earth. We tested the hypothesis that maize ( Zea mays ) genotypes with large 29 crown root number (CN) will have shallower rooting depth and improved 30 phosphorus (P) acquisition from low-P soils. Maize recombinant inbred lines 31 with contrasting CN were evaluated under suboptimal P availability in 32 greenhouse mesocosms and the field. Under P stress in mesocosms, the 33 large-CN phenotype had 48% greater root respiration, 24% shallower rooting 34 depth, 32% greater root length density in the topsoil, 37% greater leaf P 35 concentration, 48% greater leaf photosynthesis, 33% greater stomatal 36 conductance, and 44% greater shoot biomass than the small-CN phenotype. 37 Under P stress in the field, the large CN phenotype had 32% shallower rooting 38 depth, 51% greater root length density in the topsoil, 44% greater leaf P 39 concentration, 18% greater leaf photosynthesis, 21% greater stomatal 40 conductance, 23% greater shoot biomass at anthesis, and 28% greater yield 41 than the small CN phenotype. These results support the hypothesis that large 42 CN improves plant P acquisition from low-P soils by reducing rooting depth 43 and increasing topsoil foraging. The large CN phenotype merits consideration 44 as a selection target to improve P capture in maize and possibly other cereal 45 crops.
Institutional Knowledge at Singapore Management National culture and capital structure decisions: Evidence from foreign joint ventures in China

We investigate the role of firms’ country of origin in financial leverage decisions using data on foreign joint ventures in China. We hypothesize that national culture enters the joint optimization process leading to foreign joint ventures’ leverage decisions and that it affects leverage decisions both directly and indirectly. Using cultural values of mastery and embeddedness to explain country of origin effects, we find that mastery has negative and significant direct effects on foreign joint ventures’ leverage and short-term debt decisions, and a positive and significant direct effect on the likelihood of foreign joint ventures’ having long-term debt. The indirect effects of mastery on leverage decisions sometimes reinforce and sometimes offset the direct effects. Embeddedness has no significant direct effect on foreign joint ventures’ leverage decisions, but exerts its influence entirely through indirect effects. Finally, the economic significance analysis of the total effects suggests that national culture has significant explanatory power in the leverage decisions of foreign joint ventures in China. domestic firms in countries with high scores on the cultural values of mastery and embeddedness have lower corporate debt ratios. They regress country-level corporate debt ratios on mastery and embeddedness and show that both values are negatively associated with debt ratios. They also regress firm-level debt ratios on the two
STUDY OF SOME TESTICULAR DIMENSIONS AND THEIR RELATIONSHIP TO BODY WEIGHT IN KARADI RAM LAMBS

This study was carried out to measure the development of some testicular traits and to investigate the relevance between testicular parameters with body growth in growing Karadi ram lambs. Twenty-seven single born Karadi ram lambs apparently clinical healthy, aged six months, were used. The Testicular measurements including: length, diameter, and circumference of their testes and body weight were recorded once monthly. The testicular measurement (cm) and body weight (kg) were subjected to linear (Y= a+bX) where, Y means the testicular measurement and X is the body weight, a and b are constants due to the intercept and the regression coefficient, respectively. The results revealed that there was a gradual and linear increase in testicular dimensions from six to eight months of age. The average scrotal circumference (SC) showed significant (P≤0.05) increase from 10.66±0.74 to 17.88±1.19 cm at 6 and eight months of age, respectively. Corresponding changes in the average testicular volume were found to be 14.31±3.66, 77.66±23.54 and 104.23±23.92 cm 3 at 6, 7 and eight months of age, respectively. All measurements of testis, live weight, were positively and significantly correlated with each other. While a significant positive correlation were found at seven and eight months of age between all testicular measurements. These results showed that testicular measurements, such us scrotal circumference, can be used as criteria for early selection of ram lambs to be utilize in breeding especially for young ages. Due to the strong correlation between body weight and testicular measurements, body measurements can be used to select Karadi ram lambs for breeding programs. However, further studies are needed to determine the relationship between these subjective morphological criteria and the actual fertility and semen quality in Karadi rams.
RELATIONSHIP BETWEEN HEALTH OFFICER SUPPORT AND INDEPENDENCE ABILITY IN DAILY CLEAN AND HEALTHY LIFE ACTIVITIES FOR ELDERLY PATIENTS IN PUSKESMAS BRINGIN REGION

Elderly patients are patients who go through the final stages of human life span. The support of health workers is very instrumental in encouraging the interest of elderly patients to have the ability to be independent in their daily activities in a clean and healthy life. Based on the preliminary survey, it is known that elderly patients In Puskesmas Bringin Region live far from close families, so they need support from health workers to improve their independence in their daily activities in clean and healthy life. The purpose of the study was the relationship of support of health workers with the ability to be independent in the daily activities of clean and healthy life of elderly patients In Puskesmas Bringin Region. This study is analytical using a quantitative method with a cross sectional study approach. The population in the study was 130 respondents with a sample of 98 respondents. The research sample was taken by purposive sampling technique. The independent variable of this study is the support of health workers and the dependent variable of the ability of independence in daily activities of clean and healthy life. The research instrument used a questionnaire. Data were analyzed using the chi-square statistical test. The results showed that the majority of health staff support In Puskesmas Bringin Region was in the good category of 55 people (56.12%) and most of the independence ability in the daily activities of clean and healthy living In Puskesmas Bringin Region was independent as many as 66 people (67.35%). The results of this study of 98 respondents based on the results of Chi-Square test significance between the variables of health worker support and the ability of independence in daily activities of clean and healthy life is known that the value of ρ is 0.003 <α (0.05), then Ho is rejected and declared there is a relationship between the support of health workers with the ability to be independent in the daily activities of clean and healthy living In Puskesmas Bringin Region. The conclusion obtained by this study is that there is a relationship between the support of health workers with the ability to be independent in the daily activities of clean and healthy living In Puskesmas Bringin Region.
The Qualitative Report The

Abstract The purpose of the study was to explore college students’ experiences with playing World of Warcraft (WoW) and their views on the application of WoW in educational settings. A qualitative case study design was used to interview three participants who were selected purposively from a Midwestern university. Findings revealed that players thought that playing WoW was fun, relaxing, motivating, but sometimes almost to the point of addiction. The findings also support student perceptions of generalization of teamwork, cooperating, socializing, academic skills, and time management skills learned and practiced in playing WoW to academic settings. Playing WoW games can provide an important link between the virtual world and the real world as players develop academic, time management, collaborative, and critical thinking skills.
Contribuţii Botanice – 2013, XLVIII: 83-94 Grădina Botanică “Alexandru Borza” Cluj-Napoca INFLUENCE OF INORGANIC NUTRIENTS ON PARAMETERS OF BIOMASS PRODUCTION IN A LOCAL STRAIN OF THE MICROALGA

Biotechnologies based on microalgal cell cultures have multiple applications in aquaculture, the food industry, health care, environmental management, and production of alternative energy sources. In the present study we investigated the influence of nutritional conditions on bioproductive properties of a local strain of the green microalga Scenedesmus acuminatus, grown in axenic laboratory cultures, in Bold’s basal nutrient medium. Increment of nitrate concentration enhanced the biomass production, and increased protein content of the alga. Simultaneous supplement of reduced and oxidized form of inorganic nitrogen (as ammonium nitrate) did not result in an increased dry biomass, but the protein content of algal cells was significantly higher, while the carotenoid content decreased. Nitrogen deprivation increased the carotenoid pigment content of the dry algal biomass. 10 mM KHCO3 as inorganic carbon source increased biomass production, decreased protein content and did not modify significantly the carotenoid content of the alga. A higher phosphate concentration in the medium induced an increment of dry biomass and carotenoid content, but had no relevant influence on protein content. Sulphate enrichment did not modify dry biomass and carotenoid content, but caused a moderate increment of protein amount. Photosynthetic light use efficiency and vitality index of photosynthetic apparatus, evaluated with the method of induced chlorophyll fluorescence, revealed a positive influence of ammonium nitrate and of elevated nitrate content, while nitrate starvation and an excessive phosphate and sulphate supply moderately decreased the functional efficiency of light reactions of photosynthesis.
Purex Process Related Distribution Data on Neptunium {IV, VI) Kernforschungszentrum Karlsruhe

Own and published data on the extraction of Np(IV) and Np(VI) with tributyl phosphate (TBP) are gathered in the report. Purex process related data are solely considered. The scope of the gathering is limited to systems involving a 30 vol.% solution of TBP in an aliphatic diluent, and an aqueous nitrate solution. The concentration ranges in the equi librium aqueous phase are 0.1 - 11 M HN03, 0- 210 g U(VI)/1 und < 0.03 g Np(IV,VI)/1. The temperature range is 25 - 60°C. The distribution ratios of Np(IV) and Np(VI) were critically assessed and obviously erroneous values were indicated.
CMAR_A_279169 13085..13097

Department of Histology and Embryology, Nicolaus Copernicus University in Toruń, Collegium Medicum in Bydgoszcz, Bydgoszcz, Poland Background: Cyclins are well-known cell cycle regulators. The activation of cyclindependent kinases by cyclins allows orchestration of the complicated cell cycle machinery and drives the cell from the G1 phase to the end of the mitotic phase. In recent years, it has become evident that cyclins are involved in processes beyond the cell cycle. Cyclin F does not activate CDKs but forms part of the Skp1-Cul1-F-box (SCF) complex where it is responsible for protein target recognition and subsequent degradation in a proteasomedependent manner. Results: Here, we report that the downregulation of cyclin F in the A-375 melanoma cell line increases cell viability and colony formation in a cell cycle independent manner. Lower levels of cyclin F do not appear to affect the cell cycle, based on flow cytometry measuring BrdU incorporation and propidium iodide staining. By means of immunofluorescence staining and Western blot analysis, we observed changes in cell morphology-related markers which suggested ongoing epithelial-mesenchymal transition (EMT) in response to cyclin F downregulation. Increases in vimentin and N-cadherin protein levels, decreases in levels of epithelial markers such as ZO-1, along with changes in morphology to a spindle-like shape with the appearance of actin stress fibers, are all hallmarks of EMT. These changes are associated with increased invasive and migratory potential, based on 2D migration assays. Moreover, we observe an increase in RhoABC, talin and paxillin levels, the proteins involved in controlling cell signaling and motility. Lastly, upon knocking down cyclin F expression, we observed a decrease in thrombospondin-1 expression, suggesting a role of cyclin F in angiogenesis. Conclusion: Cyclin F depletion induces proliferation and EMT processes in the A-375 melanoma model.
Extended critical directions for time-control constrained problems

—We derive in this paper second order necessary conditions for certain classes of optimal control problems involving inequality and equality constraints in the time variable and the control functions. We study different normality conditions found in the literature which can be imposed on solutions to the problem and provide a new approach, partly based on the theory for constrained problems in ﬁnite dimensional spaces, which under mild assumptions allows us to enlarge the usual set of critical directions.
NEUROSYSTEMS Segregation of short-wavelength-sensitive (S) cone signals in the macaque dorsal lateral geniculate nucleus

An important problem in the study of the mammalian visual system is whether functionally different retinal ganglion cell types are anatomically segregated further up along the central visual pathway. It was previously demonstrated that, in a New World diurnal monkey (marmoset), the neurones carrying signals from the short-wavelength-sensitive (S) cones [blue–yellow (B ⁄ Y)-opponent cells] are predominantly located in the koniocellular layers of the dorsal lateral geniculate nucleus (LGN), whereas the red–green (R ⁄ G)-opponent cells carrying signals from the medium- and long-wavelength-sensitive cones are segregated in the parvocellular layers. Here, we used extracellular single-unit recordings followed by histological reconstruction to investigate the distribution of color-selective cells in the LGN of the macaque, an Old World diurnal monkey. Cells were classiﬁed using cone-isolating stimuli to identify their cone inputs. Our results indicate that the majority of cells carrying signals from S-cones are located either in the koniocellular layers or in the ‘koniocellular bridges’ that fully or partially span the parvocellular layers. By contrast, the R ⁄ G-opponent cells are located in the parvocellular layers. We conclude that anatomical segregation of B ⁄ Y- and R ⁄ G-opponent afferent signals for color vision is common to the LGNs of New World and Old World diurnal monkeys.
SYSTEMATIC REVIEW OF HELICOBACTER PYLORI INFECTION AND PLANT BASED THERAPY

[4] H. CagA blood group and possibly the duodenal is widely and in due to the plant's ability to easily adapt to salinity and winds. [5] In Asian ABSTRACT More than 50% of the world population are infected with Helicobacter pylori. The bacterium highly linked to peptic ulcer and duodenal ulcer diseases, further infection causes lifelong chronic gastritis, which can lead to peptic ulcer, mucosa-associated lymphoid tissue (MALT) lymphoma and gastric cancer. The antibiotic therapies have several inherent problems, including the appearance of resistance to the antibiotics used and associated adverse effects, such as the risk of re infection and its high cost. The decision on the therapy of invasive gastric cancer depends on several factors such as environmental factors and the presence or absence of virulent factors such as mainly Cag A, Vac A, and urease action in the gastric environment. The growing problem of antibiotic resistance by the H. pylori demands the search for novel candidates from plant-based sources. The alternative therapies have not been effective in eradicating the bacteria but have been shown to maintain the bacterial growth levels. This review summarizes pathogenesis, culture conditions and the most relevant recent studies on new treatments using natural resources such as plants.
S TIGMATIZATION AND Q UALITY OF L IFE OF M ALE - TO -F EMALE T RANSGENDER U NIVERSITY S TUDENTS IN THE N ORTHEAST OF T HAILAND

Transgender students are vulnerable to mental and physical health problems, impacting their quality of life (QOL). This research aims to study the stigma influence on the QOL of male-to-female transgender university students in Northeastern Thailand. This cross-sectional study was conducted among 765 male-to-female transgender students selected from 17 universities of the Northeast of Thailand using a multistage random sampling to respond to a self-administered structured questionnaire. The generalized linear mixed model (GLMM) was performed to identify factors associated with quality of life when controlling the effects of covariates, presenting adjusted OR and 95% confidence intervals. Among 765 male-to-female transgender students, more than half of them had good QOL (52.81%; 95%CI = 49.25-56.33). The generalized linear mixed model (GLMM) observed that factors associated with good QOL including moderate-low stigmatization (adj.OR=6.39; 95%CI = 2.72-15.02), good health behaviors (adj.OR=1.88; 95%1.47-2.86), no stress problem (adj.OR =1 . 81; 95 %CI = 1.30-2.51), good self-acceptance (adj.OR=1.67; 95%CI = 1.37-2.03) and good social environment (adj.OR=1.41; 95%CI = 1.13-1.76). These findings could provide data to support evidence for family, community, societal and relevant sectors under the Ministry of Public Health and Ministry of Education and local administration organizations to promote the quality of life in transgender people effectively.
Efﬁcacy of Human-Simulated Exposures of Tomopenem (Formerly CS-023) in a Murine Model of Pseudomonas aeruginosa and Methicillin-Resistant Staphylococcus aureus Infection (cid:1)

Tomopenem (formerly CS-023) is a novel carbapenem with improved activity against diverse hospital pathogens, including Pseudomonas aeruginosa and methicillin-resistant Staphylococcus aureus (MRSA), and has a half-life about twice longer than the half-lives of other carbapenems such as imipenem and meropenem. Our objective in this study was to estimate the efﬁcacy of tomopenem in humans by human-simulated exposures in a neutropenic murine thigh infection model against 9 clinical isolates of P. aeruginosa with MICs of 4 to 32 (cid:1) g/ml and 9 clinical isolates of MRSA with MICs of 4 to 16 (cid:1) g/ml. Human-simulated dosing regimens in neutropenic mice were designed to approximate the cumulative percentage of a 24-h period that the free drug concentration exceeds the MIC under steady-state pharmacokinetic conditions ( f % T MIC ) observed with tomopenem at 750 and 1,500 mg given as a 0.5-h infusion three times a day (TID) in humans. As reported previously, there was no difference between the target values of P. aeruginosa and MRSA required for efﬁcacy (K. Sugihara et al., Antimicrob. Agents Chemother. 54:5298-5302, 2010). Tomopenem at 750 mg showed bactericidal or bacteriostatic effects against 10 of 11 strains of P. aeruginosa and MRSA with MICs of < 8 (cid:1) g/ml ( f % T MIC > 41), and tomopenem at 1,500 mg showed bactericidal effects against 16 of 17 strains of P. aeruginosa and MRSA with MICs of < 16 (cid:1) g/ml ( f % T MIC > 43). Meropenem at 1,000 mg TID was tested for comparison purposes and showed bactericidal or bacteriostatic effects against 3 of 4 strains of P. aeruginosa with MICs of < 4 (cid:1) g/ml ( f % T MIC > 33). From these results, tomopenem is expected to be effective with an f % T MIC of over 40 against P. aeruginosa and MRSA strains with MICs of < 8 (cid:1) g/ml at doses of 750 mg TID and strains with MICs of < 16 (cid:1) g/ml at doses of 1,500 mg TID.
DETERMINANTS OF FOREIGN DIRECT INVESTMENT INTO SUB-SAHARAN AFRICA:

This study deals with to find out the main determinants of FDI in SSA countries. The studies consider countries to attract more FDI they should identify which factors are more sensitive for each countries as well as regional level. Therefore identifying the key determinants of FDI is a crucial task for policy makers. Compared to other developing countries, FDI inflow in to sub-Sahara Africa is very low, beside this study explores the role of Official Development Assistance and the landlocked effect in the attraction of Foreign Direct Investment (FDI). The study after testing which method is consistent with our data, fixed effect model is applied for the estimation of 44 SSA countries from the period 1990 to 2016 and simple OLS estimation method also applied to cheek the land looked dummy effect. The estimation results shows that Market size, Infrastructure, openness, Domestic credit to private and political stability and inflation are the key determinant in the attraction of FDI in this region. The results also show the interaction of ODA with infrastructure and ODA with political stability also has a significant effect of FDI inflow in to SSA countries. Besides, countries should also improve infrastructural development and political stabilities, as this strengthens the effectiveness of ODA in to attracting more FDI.