Miracle-dz/UniFAR-FTUs huggingface dataset:
Thyroid Dysfunction in Patients with Metabolic Syndrome and Its Relationship with Components of Metabolic Syndrome

Introduction: Iodine deficiency disorder (IDD) & Metabolic syndrome (Mets) has been associated with risk factors of cardiovascular disease (CVD). IDD is risk factor for CVD mediated by effects of thyroid hormone on lipid metabolism and blood pressure hence the components of Mets. It is possible that coexistence of these two disease entities and unrecognized IDD in patients with Mets might subsequently evaluate CVD risk. Moreover little is known about the relationship between IDD and the components of Mets. Thus the purpose of present study was to evaluate the pattern of IDD in patients with Mets and its relationship with components of Mets. Methods: A total 204 diagnosed patients with Mets were recruited in the study. The thyroid function test parameter were measured to classify IDD at Chattrapati Shivaji Hospital, Subharti Medical College, Meerut, statistical analyses were performed using SSPSS version 16.0 to evaluated pattern and relationship. Result: The overall prevalence of IDD in patients with Mets & components of Mets although there was significant difference in waist circumference of three groups of IDD. [Hypo, Hyper & subclinical thyroid disorders]. Conclusion: Present study concludes that patients with Mets had higher subclinical hypothyroidism. Although there was no evidence of any association between IDD status and all components of Mets. The IDD should be considered when evaluating & treating patients of Mets to minimize the risk.
The Role of Energy Storage Technologies for the Integration of Renewable Electricity into the German Energy System

This dissertation investigates the role of electricity storage in the context of liberalized power markets and increasing share of renewable electricity generation. The models developed in this work are used to analyze the value of storage from the investor and system perspective under different operator and market structures. Numerical case studies provide an insight into the optimal sizing and operation of various storage types with a special focus on hydrogen technology as a link between the power and mobility sectors.
Cap or No Cap? What Can Governments Do to Promote EV Sales?

This paper examines the effect of the federal EV income tax subsidy on EV sales. I find that reduction of the federal subsidy caused sales to decline by $43.2 \%$. To arrive at this result, I employ historical time series data from the Department of Energy Alternative Fuels Data Center. Using the fact that the subsidy is available only for firms with fewer than 200,000 cumulative EV sales, I separate EV models into two groups. The treatment group consists of models receiving the full subsidy, and the control group consists of models receiving the reduced subsidy. This allows for a difference in differences (DiD) model structure. To examine the robustness of the results, I conduct regression analyses. Due to a relatively small sample size, the regression coefficients lack statistical significance. Above all, my results suggest that federal incentives designed to promote EV consumption are successful in their objectives.
Interaction between thermal stratification and turbulence in channel flow

Abstract Transport phenomena in high Reynolds number wall-bounded stratified flows are dominated by the interplay between the turbulence structures generated at the wall and the buoyancy-induced large-scale waves populating the channel core. In this study, we want to investigate the flow physics of wall-bounded stratified turbulence at relatively high shear Reynolds number $Re_\tau$ and for mild to moderate stratification level – quantified here by the shear Richardson number varying in the range $0\leqslant Ri_{\tau } \leqslant 300$. By increasing stratification, active turbulence is sustained only in the near-wall region, whereas intermittent turbulence, modulated by the presence of non-turbulent wavy structures (internal gravity waves), is observed at the channel core. In such conditions, the wall-normal transport of momentum and heat is considerably reduced compared with the case of non-stratified turbulence. A careful characterization of the flow-field statistics shows that, despite temperature and wall-normal velocity fluctuations being very large at the channel centre, the mean value of their product – the buoyancy flux – vanishes for $Ri_{\tau } \geqslant 200$. We show that this behaviour is due to the presence of a $\sim {\rm \pi}/2$ phase delay between the temperature and the wall-normal velocity signals: when wall-normal velocity fluctuations are large (in magnitude), temperature fluctuations are almost zero, and vice versa. This constitutes a blockage effect to the wall-normal exchange of energy. In addition, we show that the friction factor scales as $C_f \sim Ri_{\tau }^{-1/3}$, and we propose a new scaling for the Nusselt number, $Nu \cdot Re_{\tau }^{-2/3} \sim Ri_{\tau }^{-1/3}$. These scaling laws, which seem to be robust over the explored range of parameters, complement and extend previous experimental and numerical data, and are expected to help the development of improved models and parametrizations of stratified flows at large $Re_{\tau }$.
RESPONS TEKNOLOGI DEPURASI TERHADAP KADAR TIMBAL (Pb) DALAM KERANG HIJAU HASIL PEMBUDIDAYAAN DI PANTAI BANYUURIP KECAMATAN UJUNG PANGKAH KABUPATEN GRESIK

The decrease of green mussel production in 3 years (2018 – 2020) was suspected to Pb levels on the whole organ of green mussels, which estimated to 0.7 ppm, in Banyuurip village, Ujung Pangkah, Gresik Regency. The expansion of industrial or domestic (household) activity was claimed to contribute a magnificent waste in the water. The purpose of this study was to analyze Pb levels on the whole organ of green mussles before and after the depuration. This research was implemented in Gayam, Soko Village, Glagah Sub-District, Lamongan Regency. Green mussel samples was taken from Banyuurip beach, where the green mussels culture was done. Then, 10 kg of green mussels was added to several container in size 150 L for depuration procedure. The main parameter in this research was the Pb level on the whole organ of green mussels and water media, and the other parameter was water quality (DO, pH, salinity, temperature and amonia). After performed this research, we expected to give information of depuration technology respond against Pb reduction after flushing inrecirculation system. Research used experimental method with complete random design, consist of 4 treatments and 3 repetition. P1 used as control, P2, P3, P4 (depuration method in 8, 16, and 24 h). The flushing in 24 h was removed Pb 59%, from 0.66 ppm to 0.27 ppm. As this decline, the green mussels which was cultivated by fisherman will be more safety to consume as food products. The result of this depuration with recirculation system was lower and appropriate with BPOM standardization (2009), Perikanan (DKP) No:Kep 20/Men/2004,SK Ditjen POM No. 03725/B/SK/VII/1989, which the limit of pollutan in food products was 1.5 ppm
Monetary Policy and Inequality in a Small Open Economy

We study the impact of monetary policy on income and wealth distributions in a small open economy. To do so, we use household-level registry and survey data from Finland, a small member of a monetary union. This setup allows us to circumvent endogeneity issues and thus helps achieve causal interpretation. We find that expansionary monetary shocks stimulate economic activity, earnings, and asset prices, while barely affecting income and wealth inequality. The reduction in unemployment mostly benefits households in lower income quintiles, where the initial rate of unemployment is high. Households in upper income quintiles, where the rate of employment is higher, benefit relatively more from higher wages. Higher house prices increase the net wealth of all homeowners. However, due to a leverage effect, households with large mortgages located in the lower net wealth quintiles benefit most. Rising stock prices, in turn, benefit mainly households in the top net wealth quintile. Overall, these different channels have counteracting effects on income and wealth inequality.
HIV Care continuum Outcomes: Can Ethiopia Meet the UNAIDS 90-90-90 Targets?

Background Ethiopia has pledged to the UNAIDS 90-90-90 framework. However, the achievements of these UNAIDS targets are not assessed in Southwest Ethiopia. Using HIV care and treatment outcomes as surrogate markers, we assessed all targets. Methods Complex surrogate makers were used to assess the HIV care continuum outcomes using antiretroviral therapy data in Jimma University Teaching Hospital. Early HIV diagnosis was a surrogate marker to measure the first 90. Numbers of people on HIV treatment and who have good adherence were used to measure the second 90. To measure the third 90, we used immunological success that was measured using numbers of CD4 counts, clinical success using WHO clinical stages and treatment success using immunological and clinical successes. Results In total, 8172 patients were enrolled for HIV care from June 2003 to March 2015. For the diagnosis target, the prevalence of early HIV diagnosis among patients on ART was 35% (43% among children and 33.3% among adults). For the treatment target, 5299(65%) received ART of which 1154(22%) patients lost to follow-up or defaulted from ART treatment, and 1015(19%) patients on treatment transferred out to other sites. In addition, 17% had fair or good adherence. Finally, 81% had immunological success, 80% had clinical success and 66% treatment success. Conclusions The study revealed that Southwest Ethiopia achieved 35%, 65% and 66% of the first, second and third UNAIDS targets, a very far performance from achieving the target. These highlight further rigorous interventions to improve outcome of HIV continuum of care.
Residual effects of agricultural gypsum on soil chemical and microbiological characteristics

Agricultural gypsum can improve the chemical quality of low fertility soil, providing calcium and sulphur. In this study, we evaluated the effects of agricultural gypsum application at five dosage rates (0, 3, 6, 9 and 12 Mg ha−1) on the chemical and microbial soil characteristics of an acid oxisol (0–0.1 m and 0.1–0.2 m layers) and the impact on wheat grain yield. Increasing agricultural gypsum dosage rates increased Ca, S as well as the Ca/Mg ratio and microbial biomass of carbon in the 0–01 m soil layer. In the 0.1–0.2 m soil layer, agricultural gypsum affected organic C (Corg), Ca and the Ca/Mg ratio. The microbial biomass of carbon had positive correlations with most chemical and microbial variables. In the 0–0.1 m soil, the microbial biomass of C and N had negative relationships with arylsulphatase and β‐glucosidase, respectively. At 0.1–0.2 m depth, arylsulphatase activity correlated negatively with Corg and positively with Al. Agricultural gypsum soil amendments increased the microbial biomass of carbon, especially at the highest application rate (12 Mg ha−1). The highest biochemical index activity was found in the 3 Mg ha−1 (0–0.1 m) and 9 Mg ha−1 (0.1–0.2 m) treatments. At 70 months after application, we found that maximum wheat grain yield was rendered by an agricultural gypsum application rate close to 3 Mg ha−1.
The nexus between fiscal and current account imbalances in OECD economies

ABSTRACT We re-examine the nexus between fiscal balances and current account balances for 18 OECD countries from 1995Q1 to 2018Q1 using panel cointegration and panel vector autoregressive (VAR). The findings confirm a long-run relationship between the fiscal balance and the current account balance. Our results indicate that strengthening the fiscal balance by one percentage point of GDP improves the current account balance by about 0.1–0.3 percentage points of GDP. On the other hand, an increase in real government consumption generally worsens the current account balance. The impact of the real effective exchange rate is not statistically significant.
Estresse: fatores de risco no trabalho do enfermerio hospitalar

Os objetivos deste estudo foram descrever as caracteristicas socio-demograficas e de trabalho da populacao estudada e identificar a variavel que apresenta maior risco para o estresse. A populacao, constituida por 85,7% de enfermeiros trabalhadores de um hospital, responderam a escala de estresse. Os dados foram analisados utilizando-se distribuicao de frequencia, risco relativo e teste c2 (p< 0,05). Sao do sexo feminino 87,5% dos enfermeiros; 33,4% trabalham de 10 a 15 anos e 45,8% possuem duplo vinculo. Enfrentar situacoes criticas foi a variavel com maior risco para o estresse. Verificou-se que quanto maior a faixa etaria dos enfermeiros maior o estresse para o gerenciamento de pessoal.
Interacting in Flow: An Analysis of Rapport-Based Behavior as Optimal Experience

Theorists have long noted the nebulousness of dyadic rapport and its nonverbal correlates. In response to Tickle-Degnen’s call for a more theoretically complete analysis of the rapport construct, we empirically evaluated her adaptation of Csíkszentmihályi’s optimal experience model with the hope of better conceptualizing rapport’s behavioral manifestations. Dyads ( N dyad = 50) engaged in two interdependent tasks and completed a battery of post-task measures gauging their mood and experiences of rapport. To complement self-report measures, we coded rapport-based behavior using both subjective (thin-slice judgments) and objective (Motion Energy Analysis) methodologies. According to Tickle-Degnen’s model, dyadic exchanges with moderate levels of expressivity and interpersonal coordination should yield the highest levels of rapport. Although data from our objective coding did not trend in this manner, subjective measurements of coordinated expressivity matched the paradigm’s prediction. To our knowledge, this is the first study to empirically support Tickle-Degnen’s hypothesis and a novel step toward clarifying the rapport construct.
The solar tachocline.

Acoustic sounding of the Sun reveals that the variation of angular velocity with latitude is independent of depth in the convection zone. By contrast, deep within the radiative zone, the rotation appears to be rigid. The transition between the two rotation laws occurs in a thin, unresolved layer that we here call the tachocline. This paper is an examination of the structure and previous evolution of this layer. We assume that the stress exerted by the convection zone is prescribed, much as oceanographers take the wind stress on the sea surface as given.
COVID-19 Private Pension Withdrawals and Unemployment Tenures

IZA DP No. 15399 JUNE 2022 COVID-19 Private Pension Withdrawals and Unemployment Tenures* This is the first study to evaluate the effects of early pension withdrawal policies on tenures on unemployment payments in the COVID-19 context. We use a novel set of linked wholeof-population administrative records to examine more than half-a-million Australians who found themselves newly on an unemployment payment in the initial months of the COVID-19 pandemic. We estimate that receiving a lump sum of up to A$10,000 from superannuation accounts at the most acute phase of the pandemic, between April and June 2020, resulted in a 32 per cent lower exit rate from unemployment benefits inside the first six months of a spell on benefits, and 14 per cent inside a year of spell. Receiving a lump sum during the second window of opportunity – mostly in July and August 2020 and as a labour market recovery was underway – resulted in a 34 per cent lower exit from unemployment benefits inside the first nine months of spell, and 14 per cent inside fifteen months of spell. The jobseeking deterrence is ultimately temporary but it took close to eighteen months for an estimated convergence between withdrawers and those that didn’t withdraw. 162,000 withdrawers with completed spells on average spent an additional 7 weeks on unemployment payments, translating to 8 million additional days in aggregate, and implying A$580 million in additional pandemic fiscal expenditure. JEL Classification: E24, H12, H30, H53, J32
Independent Daily Living Skills and Self-Care Capacity among Visually Impaired Child: A Descriptive Study

Introduction: Visually handicapped children unable to carry out normal activities because of defects of vision, including blindness the aim of the study was to evaluate levels of dependency of doing daily Living Skills and self-care capacity among Visually Impaired child Aim : To evaluate levels of dependency of doing daily Living Skills and self-care capacity among Visually Impaired child. Research design: A descriptive design was used in this study. Setting: This study was conducted in El Noor schools of visual handicap at Tanta city sample : It contains (9) class room with the total number of (86) students with visual handicap. Tools of Data collection: Two tools were used to collect the required data, 1:-Structured interview schedule and structured observational check list. The results : It was revealed that there were statistically significant difference between the total score of self-dependence in relation to the socio-demographic variables such as Age in years and Educational level Conclusion & Recommendations: There was a highly statistically significant relationship between total score of self-dependence and socio-demographic factors as regards to age, educational level and residence. This may be due to lack of mother's knowledge, lack of supervision, follow up of child and lack of motivation resources and facilities that affect children knowledge and performance. Therefore the study recommended in service training programs and workshops should be conducted for those children to improve their knowledge and performance, health education to mothers about self-care management to child and program about care of their child.
A high-throughput coregulator peptide array detects estrogen receptor alpha Serine-305 phosphorylation that is associated with response to tamoxifen treatment

With current techniques it remains a challenge to assess coregulator binding of nuclear receptors, e.g. the estrogen receptor alpha (ERα). ERα is critical in many breast tumors and is inhibited by antiestrogens such as tamoxifen in cancer therapy. ERα is also modified by acetylation and phosphorylation that affect responses to the anti-estrogens as well as interactions with co-regulators. Phosphorylation of ERα at Ser305 is one of the mechanisms causing tamoxifen resistance. Detection of resistance in patient samples would greatly facilitate clinical decisions on treatment, where such patients would receive other treatments such as aromatase inhibitors or fulvestrant. Here we describe a coregulator peptide array that can be used for high throughput analysis of full-length estrogen receptor binding. The peptide chip can detect ERα binding in cell and tumor lysates. We show that ERα phosphorylated at Ser305 associates stronger to various coregulator peptides on the chip. This implies that ERαSer305 phosphorylation increases estrogen receptor function. As this is also detected in a breast tumor sample of a tamoxifen insensitive patient, the peptide array as described here may be applicable to detect tamoxifen resistance in breast tumor samples at an early stage of disease and contribute to personalized medicine.
Recognizing the Native Receptor Allows Production of Monoclonal Antibodies Thyrotropin Receptor Causes Thyroiditis and Genetic Immunization Against the Human

The generation of Abs recognizing the native structure of the human thyrotropin receptor (hTSHR) has been difﬁcult because there is currently no method allowing the puriﬁcation of correctly folded Ag in the amounts required by classical immunization protocols. The majority of Abs made against the hTSHR react preferentially with denatured molecules. We report that a humoral response against the native hTSHR, compatible with mAb production, is elicited in mice by immunization with a DNA construct encoding the receptor. BALB/c mice were inoculated in the anterior tibialis muscle with 100 m g of plasmid DNA harboring the hTSHR cDNA. Eleven weeks after the ﬁrst injection, 10 mice of 14 showed by FACS analysis a strong IgG response against the hTSHR expressed at the surface of Chinese hamster ovary cells. A clear TSH-binding inhibiting Ig and thyrotropin-blocking Ab activity (competition with TSH binding and TSH activity, respectively) was demonstrated in the majority of sera tested. One serum exhibited a clear stimulating activity. Despite the maintenance of normal circulating free T4 levels in all mice, these bioactivities persisted until 18 wk, in which mice were sacriﬁced, their thyroids were examined histologically, and spleens from two animals were used for mAb production. All mice displayed a severe lymphocytic inﬁltration of their thyroids, composed mostly of activated B cells. Three mAbs were produced against conformational epitopes of the hTSHR. We conclude that genetic immunization is an efﬁcient method of generating Abs recognizing the native structure of the hTSHR and a new way of inducing thyroiditis in mice murine. The Journal of Immunology, 1998, 160: 1458–1465.
Insecticide resistance in Australian populations of Western Flower Thrips, 'Frankliniella occidentalis' (Pergande) (Thysanoptcra: Thripidae)

Insecticides are the main method of Western Flower Thrips (WFT) control in Australia and their effective management is underpinned by resistance monitoring of field populations. Surveys conducted between 2003 and 2006 did not detect resistance to acctamiprid, dimethoatc, mcthamidophos or thiamethoxam but, low level resistance was detected against abamcctin, accphatc, chlorpyrifbs, dichlorvos, cndosulfan, fipronil, malathion, mcthidathion, methiocarb and mcthomyl. Worryingly, high level resistance was detected to alpha-cypcrmcthrin (25x) and spinosad (87x). Spinosad is now the most widely used registered product for WFT control. Loss of spinosad would jeopardise the WFT control strategy so it is imperative that the resistance is effectively managed.
Medical and Surgical Treatment Options for Early Osteonecrosis in Sickle Cell Disease

Sickle cell disease is one of the most common genetic disorders and the first molecular disease identified. Osteonecrosis defined as necrosis of bone and bone marrow. It occurs with sickle cell disease due to the polymerization of the sickle cell hemoglobin HbS, which followed by sickling and dehydration of the red blood cells. That causes slowing down of blood circulation and obstruction of the microcirculation leading to osteonecrosis. Many medical and surgical measures could be applied to reserve the joints with osteonecrosis from collapse and may be to avoid major surgical interventions. Both the hematologist and the orthopedics treating their sickle cell patients need to be aware of these available measures. The future trend also promising with the new hypo methylating drugs, new anticoagulants, autologous stem cell-based therapy, and many other new agents could be used to improve osteonecrosis and other sickle cell disease complications.This article reviews a subject poorly discussed in the literature from medical and surgical prophylactic and treatment points of view for the early detected osteonecrosis.
Lifestyle behaviours associated with body fat percent in 9-11-year- 1 old children

To examine [1] associations between body fat percent (BF) and lifestyle behaviours in 5 children aged 9-11 years, and [2] the consistency of these associations over a 10-year period. In this repeat, cross-sectional study, 15,977 children aged 9-11 years completed an 8 anthropometric assessment and the SportsLinx Lifestyle survey between 2004 and 2013. Body 9 fat was estimated according to the sum of the tricep and subscapular skinfold measurements. 10 Multilevel models were utilized to examine associations between BF and responses to the 11 lifestyle survey, while controlling for known covariates.