Miracle-dz/UniFAR-FTUs huggingface dataset:
Gene Therapy for Peripheral Arterial Disease and Nursing Implications: Clinical Experience on the use of Sendai Viral Vector

Current trends in gene therapy affect nursing practice and research. As treatments with gene therapy progress, nurses are required to have advanced knowledge and techniques to provide nursing care for patients who undergo gene therapy. The challenges for nurses are adherence to ethical and regulatory guidelines, detailed knowledge of gene transfer and safety issues in the use of viral vectors, the ability to monitor unspecified symptoms, and the provision of non-standardized care for patients. In this article, the authors discussimplications for specialized nursing related to the use of virus vectors in gene therapy, with a focus on peripheral arterial disease.
Investigating the relationship between personality dimensions, level of self-efficacy and perceived performance appraisal satisfaction: a case for individualised performance appraisals

1 Investigating the Relationship between Personality Dimensions, Level of Self-Efficacy and Perceived Performance Appraisal Satisfaction: A Case for Individualised Performance Appraisals Jodi Milosevich MLSJOD001 Supervisor: Professor Anton F. Schlechter A dissertation submitted in partial fulfilment of the requirements for the award of the Degree of Master of Commerce in Organisational Psychology Faculty of Commerce University of Cape Town 2019
Effect of crocin and naringenin supplementation in cryopreservation medium on post-thawed rooster sperm quality and expression of apoptosis associated genes

The aim of our research was to examine the effects of crocin (0.5 (C0.5), 1 (C1) and 1.5 (C1.5) mM) and naringenin (50 (N50), 100 (N100) and 150 (N150) µM) in cryopreservation extender for freezing rooster semen. Sperm motility, viability, abnormalities, membrane integrity, mitochondrial activity, apoptosis status, lipid peroxidation (LP), GPX, SOD, TAC, the mRNA expression of pro-apoptotic (CASPASE 3) and anti-apoptotic (Bcl-2) genes, fertility and hatchability rate were investigated following freeze-thawing. C1 and N100 resulted in the higher (P < 0.05) total motility and progressive motility in comparison to the control group. C1 and N100 improved viability, membrane integrity and reduced lipid peroxidation. We found much higher values for mitochondria activity with C1 and N100 respect to the control group. The C1 and N100 showed lower percentages of early apoptosis when compared with control group. Also, C1 and N100 had higher TAC when compared with control group. The mRNA expression of BCL-2 in the C1 and N100 group were significantly higher than that of other treatments. The expression of CASPASES 3 was significantly reduced in C1 and N100 group (P < 0.05) when compared to control group. Significantly higher percentage of fertility and hatching rate were observed in C1 and N100 compared to the control group. In conclusion, crocin at 1 mM and naringenin at 100 µM seem to improve the post-thawing rooster semen quality, fertility and could protect the sperm against excessive ROS generation by reducing the pro-apoptotic (CASPASE 3) and increasing anti-apoptotic (Bcl-2) genes.
Triple Bottom Line Reporting and Shareholder's Value in Oil and Gas Marketing Firms In Nigeria

Noticeable gap exists between the company and the stakeholders when the company focuses on single bottom reporting that only shows profitability at the expense of environment and society. This paper evaluates the effect of triple bottom line disclosures on economic value, market value and cash flow returns on investment of the studied companies. Secondary data were from the NSE Fact Book and Annual Reports of studied companies quoted in NSE. A disclosure checklist of GRI guidelines was used while employing the ex post facto design. All the twelve quoted Oil and Gas companies were studied for ten years with descriptive statistics and panel data regression analysis employed. The findings showed that economic, social and environmental performance disclosures significantly affect economic value, market value and cash flow returns on investment. These results confirm that corporate strategies of reporting the organization’s footprints on the basis of environment, social and economic conditions of stakeholders significantly maximize shareholders’ value.
A Case Study on Faculty and Professional Advisor Perceptions on Academic Advising

This case study addresses the attitudes and perceptions of faculty and professional advisors at a public comprehensive liberal arts institution. Based on a survey administered to full-time faculty and professional advisors in Fall 2009, the results showed a quantitative difference in levels of satisfaction with advising between the groups. Faculty reported a desire to function more in a mentoring capacity as well as increased recognition for advising during the promotion and tenure process, and identified a systemic need for better communication of policies and procedures. Professional advisors also raised these concerns but reported a higher level of overall satisfaction with advising. Concrete strategies to improve advising delivery were identified. Some preliminary best practices are addressed.
Evaluating Crowdsourced Design Concepts With Machine Learning

Automation has enabled design of increasingly complex products, services, and systems. Advanced technology enables designers to automate repetitive tasks in earlier design phases, even high level conceptual ideation. One particularly repetitive task in ideation is to process the large concept sets that can be developed through crowdsourcing. This paper introduces a method for filtering, categorizing, and rating large sets of design concepts. It leverages unsupervised machine learning (ML) trained on open source databases. Input design concepts are written in natural language. The concepts are not pre-tagged, structured or processed in any way which requires human intervention. Nor does the approach require dedicated training on a sample set of designs. Concepts are assessed at the sentence level via a mixture of named entity tagging (keywords) through contextual sense recognition and topic tagging (sentence topic) through probabilistic mapping to a knowledge graph. The method also includes a filtering strategy, the introduction of two metrics, and a selection strategy for assessing design concepts. The metrics are analogous to the design creativity metrics novelty, level of detail, and a selection strategy. To test the method, four ideation cases were studied; over 4,000 concepts were generated and evaluated. Analyses include: asymptotic convergence analysis; a predictive industry case study; and a dominance test between several approaches to selection of high ranking concepts. Notably, in a series of binary comparisons between concepts that were selected from the entire set by a time limited human versus those with the highest ML metric scores, the ML selected concepts were dominant.
Using Visible and Near-IR Light to Facilitate Photobiomodulation: A Review of Current Research

This review article summarizes the work of our research team. We are engaged in efforts to evaluate the effect of visible and near-IR light on various biologic tissues. Much of our work has dealt with the antimicrobial effect of light. Those examples are discussed in the paper. We are also engaged in examining the use of light to positively address deficits associated with peripheral neuropathies and musculoskeletal injuries. This review article is not intended as a comprehensive treatment of low level light therapy, but rather is intended to summarize our research agenda. We hope this summary can serve as a part of the basic science foundation that will lead to effective use of light energies as an alternative, if not adjunctive, therapy to inhibit the growth of microorganisms that threaten human health and to assist in the management of pain and inflammation associated with soft tissue injury and peripheral neuropathy.
Candida balanitis. Clinical and mycological study about the efficacy of a single-day oral treatment with itraconazole (400 mg)

© Our Dermatol Online 1.2020 1 How to cite this article: Bonifaz A, Tirado-Sánchez A, Jaramillo-Manzur C, Araiza J, Fierro-Arias L. Candida balanitis. Clinical and mycological study about the effi cacy of a single-day oral treatment with itraconazole (400 mg). Our Dermatol Online. 2020;11(1):1-5. Submission: 23.06. 2019; Acceptance: 24.08. 2019 DOI: 10.7241/ourd.20201. 1 Candida balanitis. Clinical and mycological study about the effi cacy of a single-day oral treatment with itraconazole (400 mg)
A program assessment: barriers and facilitators to the implementation of the Teen Talk Peer Support Training Program and the impact of the Peer Support Training on participants in Rural and Northern Manitoba

One response by the Manitoba Government to STI/HIV rates among its youth has been the support of a Youth Health Education Service named Teen Talk. Teen Talk has developed two programs, the Workshops for Youth Program and the Peer Support Program. In this mixed methods research study, the barriers and facilitators to implementing the Peer Support Program (PS) beyond the limits of the City of Winnipeg and the impact of the PS training on its participants were documented. The results were organized into categories and diagrams were created. It was concluded that in order for the PS training to best meet the needs of its rural and northern participants, Teen Talk needs to become a part of larger community wide initiatives. Within Teen Talk a paradigm shift needs to occur where rural and northern training sessions are acknowledged as separate entities and appropriate financial and human resources are allocated.
Childhood Trauma, Quality of Life, Sleep Quality, Anxiety and Depression Levels in People with Bruxism.

Introduction The aim was to investigate the relation between sociodemographic features, anxiety, depression, sleep quality, childhood trauma experiences, and quality of life and bruxism determining the risk factors in people with bruxism. Methods A total of 200 people were included in the study. Of the patients, 100 were diagnosed with bruxism and 100 were included in the control group. Sociodemographic Data Form, Hospital Anxiety Depression Scale (HAD), The Pittsburgh Sleep Quality Index (PSQI), Childhood Trauma Scale (CTS), Short Form-36 Quality of Life Scale (SF-36) were used. Results While there was no significant difference between the case group and the control group in terms of age, gender, marital status, and working status, there was a significant difference between educational levels. When the groups were compared a significant difference was found with regard to HAD-A (p<0.05), HAD-D (p<0.01), PSQI (p<0.01) and CTS (p<0.05) scores. While a significant difference was found when KF-36 subscales were examined, with regard to Physical Function (p<0.01), Pain (p<0.05), Social Function (p<0.05) and Mental Health (p<0.01) scores, no significant difference was detected between the subscales of Role Strength (p>0.05), General Health (p>0.05), Vital Energy (p>0.05) and Emotional Role (p>0.05). Regression analysis shows, (PSQI), HAD-D CTS scores predicted bruxism. Conclusion Higher depression scale scores, bad sleep quality, traumatic childhood experiences increase the risk for bruxism. Paying attention to the mental state of people diagnosed with bruxism in the treatment process and incorporating the psychiatrists in this process may increase the success rate of the treatment.
Celebrity-bashing or #MeToo contribution? New York Times Online readers debate the boundaries of hashtag feminism

ABSTRACT In January 2018, a feminist blog, babe, detailed an anonymous woman’s date with comedian Aziz Ansari, ending with her accusation that he had sexually assaulted her by escalating his sexual advances despite her verbal and nonverbal objections. Online reaction to the babe article was swift and plentiful, including a New York Times editorial written by conservative provocateur Bari Weiss entitled, “Aziz Ansari is Guilty. Of Not Being a Mind Reader. ” Weiss’ piece drew 2953 online responses before the comment section closed the next day, with wide-ranging views addressing the respective behaviors and motivations of Ansari, “Grace,” and Weiss. The responses provide an opportunity to explore how commenters negotiate the boundaries of the #MeToo movement in the venue that had ignited the movement’s resurgence with the story of movie mogul Harvey Weinstein’s longstanding sexual abuse of women working in the film industry. This study applies quantitative and qualitative analysis to comment discourse and elicits three major themes: (1) expectations for seeking or conveying consent, (2) criteria for publicizing the private, and (3) demarcations between insensitivity and abuse. Justifications frequently offered for the positions articulated were based on references to personal experience, cultural expectations, the #MeToo movement, and feminism.
The prevalence of diabetes and metabolic syndrome and associated risk factors in Sudanese individuals with gallstones: a cross sectional survey.

Background The gallstones are common health problem across the world with huge financial burden on health authorities. Obesity and insulin resistance are associated with risk of gallstones disease (GSD). The aim of this study was to assess the prevalence of metabolic syndrome (MetS) and diabetes and associated risk factors in Sudanese patients with gallstones. Methods A prospective cross-sectional study, enrolled patients with gallstones attending Ibn Sina Specialized Teaching Hospital for gastrointestinal and hepatobiliary diseases. A structured questionnaire was applied, anthropometric measures were taken, and blood tested for HbA1c, fasting glucose and lipid profile. Data was analysed using SPSS version 23. Results A total number of 151 participants were recruited in the study, 71 of them were ultrasound confirmed GSD patients, and the other 80 were controls without GSD over a period of six months. The prevalence of the MetS and diabetes was 30% and 23.9% respectively. Borderline diabetes was 16.9% and overweight and obesity constituted more than half of the sample 59.6%. Using Chi-Square test, a statistically significant association was found between MetS and HDL, TG, LDL level, waist circumference and blood pressure (BP). Absolute predictors and the risk factors for gallstone disease were waist circumference, age, HbA1c and LDL. Conclusions The prevalence of MetS and diabetes among gallstone patients was 30% and 23.9% respectively. Absolute predictors and the risk factors for gallstone disease were waist circumference, age, HbA1c and LDL.
Contrasting the Effect of Forest Landscape Condition to the Resilience of Species Diversity in a Human Modified Landscape: Implications for the Conservation of Tree Species

Using landscape moderation insurance and Intermediate Disturbance Hypothesis (IDH) as frameworks, this study assessed the response of local assemblage among different land use regimes (mean β-diversity), using the Jaccard dissimilarity matrix in contrasting Human Modified Forest Landscapes (HMFLs). The study was conducted at the relatively simplified Mafhela Forest Reserve and the complex Thathe Vondo Forest Reserve in South Africa. The patterns of overall β-diversity between HMFL and State-protected Indigenous Forests (SIF) were compared and the leading change drivers were then untangled. This study found that human disturbance affects mean β-diversity of local assemblages among land use regimes between the two HMFLs in an ecologically contrasting manner. The HMFL in Mafhela Forest Reserve had distinct local assemblages among land use regimes and did not conform to the expectation of IDH. On average, HMFL had the same average local species richness as SIF, mainly due to change in species composition (species replacement) induced by land use disturbance. Land use intensity gradient was the leading change driver to explain the overall β-diversity of the Mafhela Forest Reserve. The findings in the Thathe Vondo Forest Reserve were in contrast with the Mafhela Forest Reserve. Although on average the HMFL had the same local species richness as SIFs, this was mainly due to a trade-off of species gain in trees along the rivers and streams and species loss in Culturally Protected Areas (sacred forests) (CPA) as expected by IDH. The contrasting findings imply that the effectiveness of any alternative conservation strategy is context-dependent. The resilience of local assemblages and conservation value of HMFL depends on the condition of the overall forest landscape complexity and cannnot be captured by one theory, nor by one species diversity matrix (e.g., β-diversity or Richness). It thus demands the application of complementary theoretical frameworks and multilevel modeling.
Dengue infection: its prevalence with seasonal variations

Background: Dengue fever is emerging arbo-viral acute febrile illness, which is endemic in India. Continuous surveillance of dengue fever is important for the proper and timely institution of vector control measures. With this study we made an attempt to know seasonal variation of incidence of dengue infection and correlation between thrombocytopenia and leucopenia in dengue positive cases. Apart from dengue serological markers platelet count and leucocyte count are also important in proper management of dengue infected cases. Methods: This study was conducted in department of Microbiology Al-ameen medical college Vijaypur from January 2014-december 2015. Serum samples were collected from patients suspected with dengue fever and dengue serology was done using immunocrhomatographic card test, along with this platelet count and total count was done by automation. Results: Of 284 samples received 58 (20.42%) samples were positive for one or more parameters of dengue. 27(46.55%) samples were positive for only NS1, 4(6.89%) were positive for only IgM, 14(24.13%) were positive for only IgG. Remaining 13 were positive for more than one serological markers. 36.26% of dengue positive cases had thrombocytopenia whereas only 4.28% of dengue negative cases had thrombocytopenia. 55.17% of dengue positive cases had leucopenia whereas only 12.38% of dengue negative cases had leucopenia. The increase incidence of cases coincides with the mason and post monsoon season. Conclusion: Incidence of dengue infection was higher in monsoon and post Manson period. Thrombocytopenia and leucopenia provide high suspicion of dengue infection, mainly where dengue serological tests are not available. Keywords: Dengue fever, NS1 antigen, IgM antibody, Seasonal, Platelet count
Clinical and Endoscopic Profile of Periampullary Tumour in a Tertiary Care Hospital

Background and aims: Periampullary tumour is a clinical condition often encountered by gastroenterologist and surgeon. There is limited data regarding clinical profile and endoscopic management of patients with periampullary tumour. Methods: We retrospectively analyzed the ERCP (Endoscopic retrograde cholangio pancreatography) records of periampullary tumour patients who were referred to Department of Gastroenterology for ERCP over a period of three years from January 2015 to January 2018. Demographic profile, clinical findings and ERCP management were taken into consideration. Statistics used were mean and standard deviation for continuous variables, frequencies and percentages were calculated for categorical Variables were determined. Results: We retrospectively analyzed 86 patients who had undergone ERCP for Periampullary tumours from January 2015 to January 2018. Data interpretation revealed, that majority of the cases were between 41 to 50 years (23.6 %). There was a male preponderance (66.3%). Maximum number of cases were of ampullary growth (46.5 %), followed by lower CBD stricture (32.6 %). The predominant presenting symptom was jaundice (77.9%), followed by abdominal pain (54.6 %). 12 patients (14%) had cholangitis at presentation. Mean bilirubin in the current study ranged from 11.76 to 23.72. CBD cannulation was achieved in 98.8% cases (Selective cannulation 65.1%, precut sphincterotomy 33.7%). Biliary drainage was done using plastic biliary stent (PC) in 84.7% and SEMS (self-expandable metallic stent) in 15.2% cases. Ampullary growth biopsy and biliary brush cytology revealed malignancy in 55% and 35.7% cases respectively. At 3 months, 4 patients with PC stent developed block. Conclusion: In our study, ampullary growth was the most common type of Periampullary tumour. Cholangitis was present in 14% cases at presentation. ERCP had good success for biliary drainage.Ampullary growth biopsy and biliary brush cytology has sensitivity rate of 50% and 35.7% respectively. Rate of PC stent block was low (< 5%).
What I think of school: perceptions of school by people with intellectual disabilities

Abstract For people with intellectual disabilities who do not enter the labour market, school is usually the main chapter of their socialization with the wider society. Nevertheless, little is known about their long-term perceptions of this period. We conducted interviews and focus groups on the school experiences of 16 Portuguese adults with intellectual disabilities. Results show differences between older and younger participants in their accounts of social relations and educational methods, which result from changes in special educational policies in Portugal. Overall, members of both groups evaluate their school experience positively. Our results indicate that although there is a move towards more inclusive schools, discrimination is still prevalent. These results are discussed in terms of their psychosocial consequences, as well as their implications for educational policies, and inclusion. This study contributes to a better understanding of the school experiences of people with intellectual disabilities and how policies impact them.
Should Firms Use Both Prosocial Incentives and Monetary Incentives to Motivate Workers?

This paper experimentally investigates whether firms should use both prosocial incentives and monetary incentives to motivate workers. We conduct a real-effort experiment on a data entry job. It is found that prosocial incentives will likely reduce work quality. When worker’s compensation does not include prosocial incentives, making the compensation conditional on the quality of work performed greatly enhanced the work quality. However, when worker’s compensation includes prosocial incentive, making the compensation conditional on the work quality no longer improve work quality. This suggests that prosocial incentive induces some workers to work less professionally.
Influence of Factors on the Adoption and Use of ICT-Based eHealth Technology by Urban Corporate People

The aim of this study is to investigate the influence of the factors that affect the use of a PHC system (portable health clinic, an eHealth technology) by urban corporate people in Bangladesh. This study uses the first and second versions of the technology acceptance model and the unified theory of acceptance and use of technology model as the foundation. Additionally, health awareness factors are incorporated to develop the research model. Structural equation modeling was used to analyze a sample size of 264 urban corporate people in Bangladesh. Based on the total effects, the key to promoting the future use of a PHC system lies in the three most important factors: perceived usefulness (0.659), intention to use (0.454), and health awareness (0.447). These factors have a positive and direct influence on use. The findings offer proactively important and practical guidelines to service providers, implementers, and policymakers to promote the use of eHealth technology for regular health checkups.