Miracle-dz/UniFAR-FTUs huggingface dataset:
Appropriate Technology for Screening, Diagnosis, and Evaluation of Neonatal Congenital Heart Disease in the Southernmost Region of China

Background: Early detection, diagnosis, and treatment of children with CHD has been the focus of research attention. Hainan is the southernmost underdeveloped province in China, where the technology of screening, diagnosis, and treatment for children with CHD has not been fully developed. Objectives: This study aimed to introduce and promote an appropriate technology system for screening, diagnosis, and evaluation of neonatal CHD. Methods: Two indicators, namely cardiac auscultation plus pulse oximetry (POX), were used by screening staff to screen live newborns within six to 72 hours after birth at all screening institutions in Hainan province from January 1, 2019, to December 31, 2021. Diagnosis procedure for the screened-positive newborns was performed in 31 certified medical institutions, and evaluation procedure for the newborns confirmed with CHD was performed in six certified medical institutions. Data about screening, diagnosis, evaluation, and treatment were obtained, uploaded, and managed online through a neonatal CHD screening information management net. Results: A total of 321447 live births were included in the CHD screening project, and an overall screening rate of 97.59% (321447/329387) was determined. According to our results, 8032 cases were screened-positive. A total of 1099 cases of CHD were confirmed, suggesting a CHD prevalence of 3.419 per 1000 live births. Atrial septal defect (ASD) was the most common CHD lesion, with a prevalence of 1.313 per 1000 live births. The sensitivity of cardiac auscultation, POX, and two indicators’ combination (i.e., cardiac auscultation plus POX) for CHD detection were 69.15%, 33.49%, and 91.90%, respectively; and the specificity of them were 98.36%, 99.43%, and 97.81%, respectively. The ratio of both positive in two indicators among the children with major (serious and critical) CHD at the initial screening was significantly higher than that of single positive in any indicator (χ2 = 59.455, P < 0.001). All children with CHD were evaluated, out of who 154 children with major CHD were treated promptly. Only 15 cases of children with major CHD died, and the standardized mortality of children aged 0 - 1 years with CHD was 4.67/100,000. Conclusions: It was concluded that the combination of two indicators (i.e., cardiac auscultation plus POX) for CHD screening was reliable as well as non-invasive, simple, and easy to operate so that it was conducive for promotion. It was also found that introducing and promoting an appropriate technology for screening, diagnosis, and evaluation of neonatal CHD were extremely significant since they may have contributed to the timely diagnosing and treating children with CHD, especially those with major CHD.
Utilization from ultraviolet to infrared light for CO2 reduction with P4O10/TiO2 photocatalyst

This study aims to extend the light spectrum which could be absorbed by TiO2 to infrared ray light (IR) by loading P4O10 in order to promote the CO2 reduction performance of TiO2 photocatalyst. Three ranges of light with P4O10/TiO2 film are studied, which are ultra violet light (UV) + visible light (VIS) + IR, VIS + IR, and IR only. This study also investigates the impact of molar ratio of CO2/H2O or CO2/NH3 on the CO2 reduction characteristics of P4O10/TiO2 film. The largest CO2 reduction performance in case of CO2/H2O and CO2/NH3 is obtained at CO2:H2O = 1:1 and CO2:NH3 = 3:2 respectively, irrespective of light illumination condition. With IR light illumination only, the largest molar quantity of CO per unit weight of photocatalyst for P4P10/TiO2 film in case of CO2/H2O and CO2/NH3 is 2.36 mmol/g and 33.4 mmol/g, respectively.
Estimating Unattenuated Correlations With Limited Information About Selection Variables

Correcting attenuated correlations from selected samples is a common goal in organizational settings. Hunter and Schmidt introduced a procedure, called Case IV, for correcting correlations when a researcher has no information on the variable(s) used by an organization to form a suitability judgment. In this article, we compare Case IV to two other comparable procedures: the first correction (the expectation maximization algorithm) requires raw data about the selection variables used to form a suitability judgment. The second, the Pearson-Lawley correction, requires the variance-covariance matrix of the selection variables. We show that even when the variables used for selection are unobserved or unavailable, it is still possible to estimate parameters without making the restrictive assumptions of Case IV. In addition, these two corrections almost always outperform Case IV, particularly when the critical assumption of Case IV is violated. We also provide R code illustrating the use of these correction procedures.
Effects of Oxidative Stress on Airway Epithelium Permeability in Asthma and Potential Implications for Patients with Comorbid Obesity

Abstract 20 million adults and 4.2 million children in the United States have asthma, a disease resulting in inflammation and airway obstruction in response to various factors, including allergens and pollutants and nonallergic triggers. Obesity, another highly prevalent disease in the US, is a major risk factor for asthma and a significant cause of oxidative stress throughout the body. People with asthma and comorbid obesity are susceptible to developing severe asthma that cannot be sufficiently controlled with current treatments. More research is needed to understand how asthma pathobiology is affected when the patient has comorbid obesity. Because the airway epithelium directly interacts with the outside environment and interacts closely with the immune system, understanding how the airway epithelium of patients with asthma and comorbid obesity is altered compared to that of lean asthma patients will be crucial for developing more effective treatments. In this review, we discuss how oxidative stress plays a role in two chronic inflammatory diseases, obesity and asthma, and propose a mechanism for how these conditions may compromise the airway epithelium.
The Nexus Between IT Capabilities and Firm Innovation Performance: The Mediating Effect of Supply Chain Agility

This study investigates the impact of IT capabilities on firm innovation performance. Further, it examines the mediating role of supply chain agility (SCA) as well as the moderating effect of innovation orientation (IO). The proposed conceptual model draws on resource-based view (RBV) theory. Dataset of 335 responses was analysed with process MACRO using SPSS 24.0 and AMOS. The findings show that IT capabilities positively affect firm innovation performance and SCA mediates the relationship of IT capabilities and firm innovative performance. Finally, results also confirm the moderating effect of IO between the IT capabilities and SCA.
The role of social support and stress coping strategies in genetic screening for cancer predisposition – BRCA testing as an example

Individuals with monoallelic pathogenic variants in BRCA1/BRCA2 genes are at an increased risk of developing breast or ovarian cancer. The results of genetic tests may present a stressor related to the fear associated with the impact of the diagnosis on an individual’s future.The aim of the study was to verify the level of depression, anxiety, and stress in individuals waiting for the results of BRCA genetic tests. How personality traits, stress coping strategies and social support influence the level of mental discomfort was examined.82 consecutive individuals completed an anonymous online survey consisting of basic information and five questionnaires: the Inventory for Measuring Coping with Stress (Mini-COPE), the Depression, Anxiety and Stress Scale (DASS-21), the Generalized Anxiety Disorder 7-Item Scale (GAD-7), Polish adaptation of the Ten Item Personality Inventory test (TIPI-PL), and the Berlin Social Support Scales (BSSS). Participants obtained the highest scores in Mini-COPE strategies: active coping, planning, positive reframing, acceptance, and seeking emotional support. The results of DASS-21 and GAD-7 indicate the level of depression, anxiety, and stress mainly in the normal range. The highest scores in the TIPI-PL test were obtained on the conscientiousness, agreeableness, and extraversion scales. Participants, who have already obtained the results had higher scores on the Need for Support Scale (BSSS). In general, the situation of BRCA genetic testing is not causing significant negative mental discomfort. Nonetheless, the results indicate a significant role of social support in coping with stress in individuals who have already obtained the results of their genetic test.
Spectral and Spatial Discriminant Analysis for Fused Feature Extraction in Hyperspectral Images

The fusion of valuable spectral and spatial features can significantly improve the performance of high resolution hyperspectral images classification. In this paper, we propose a spectral and spatial feature extraction method based on discriminant analysis. To increase the class discrimination, we maximize the between-class scatters and minimize the withinclass scatters. To include the spatial information in the feature extraction process, we estimate the spatial scatters in a spatial neighborhood window with multi-scale fashion. We compare our proposed method, which is called spectral-spatial discriminant analysis (SSDA), with some spatial-spectral feature extraction methods included original spectral bands plus Gabor filters, gray level co-occurance matrix (GLCM), and morphology profiles and also with some popular spectral feature extraction methods such as nonparametric weighted feature extraction (NWFE) and locality preserving projection (LPP). Moreover, we compare SSDA with some recently proposed spectral-spatial classification approaches. The experimental results on two real hyperspectral images show the good performance of SSDA compared to the competitor methods.
Revisiting Raindrop Axis Ratios Based on 3D Oblate Spheroidal Reconstruction: 2D Video Disdrometer Observations During Tropical Cyclone Passages

Raindrops are usually parameterized by oblate spheroids with axis ratios (ARs) determined from projected images. However, the adequacy of representing the 3‐Dimensional (3D) nature of raindrops with their 2‐Dimensional (2D) shadows remains an open question. This study reexamines raindrop AR parameterizations by applying a 3D oblate spheroidal reconstruction algorithm to 2D video disdrometer (2DVD) observations during the passages of 14 tropical cyclones. The results reveal an appreciable AR overestimation for large raindrops when retrieved from a single camera and especially for 2DVD raw products. This overestimation propagates into the simulated differential reflectivity (ZDR), resulting in an underestimation of ZDR by up to 0.5 dB at X‐band when large raindrops dominate the raindrop size distribution (RSD), which would introduce an underestimation of more than 20% for heavy rain rate (>60 mm hr−1) estimation by polarimetric radar. In precipitating systems with drastically changing RSDs, the importance of adopting more realistic ARs is warranted.
Proton Flux Variations During Solar Energetic Particle Events, Minimum and Maximum Solar Activity, and Splitting of the Proton Belt in the South Atlantic Anomaly

The analysis of the proton flux variations observed by the Energetic Particle Telescope (EPT) at energies >9.5 MeV from the launch of PROBA‐V satellite on 7 May 2013 up to October 2022 shows an anti‐correlation between the proton fluxes and the solar phase. At solar minimum, the fluxes are higher at low L corresponding to the northern border of the South Atlantic Anomaly (SAA). This solar cycle modulation of the inner belt is mainly due to losses by increased atmospheric interactions during solar maximum. Strong Solar Energetic Particle (SEP) events, like in January 2014, June 2015, and September 2017, inject energetic protons at high latitudes, but not in the inner belt where protons are trapped at long term at low L. Nevertheless, big geomagnetic storms, including those following SEP a few days after, can cause losses of protons at the outer border of the proton belt, due to magnetic field perturbations. A double peak in the proton belt is observed during long period of measurements only for the EPT channel of 9.5–13 MeV. The narrow gap between the two peaks in the inner belt is located around L = 2. This resembles to a splitting of the proton belt, separating the SAA into two different parts, North and South. The high‐resolution measurements of PROBA‐V/EPT allow the observation of small‐scale structures that brings new elements to the understanding of the different source and loss mechanisms acting on the proton radiation belt at LEO.
Effects of Leptin and Body Weight on Inflammation and Knee Osteoarthritis Phenotypes in Female Rats

Leptin is a proinflammatory adipokine that contributes to obesity‐associated osteoarthritis (OA), especially in women. However, the extent to which leptin causes knee OA separate from the effect of increased body weight is not clear. We hypothesized that leptin is necessary to induce knee OA in obese female rats but not sufficient to induce knee OA in lean rats lacking systemic metabolic inflammation. The effect of obesity without leptin signaling was modeled by comparing female lean Zucker rats to pair fed obese Zucker rats, which possess mutant fa alleles of the leptin receptor gene. The effect of leptin without obesity was modeled in female F344BN F1 hybrid rats by systemically administering recombinant rat leptin versus saline for 23 weeks via osmotic pumps. Primary OA outcomes included cartilage histopathology and subchondral bone micro‐computed tomography. Secondary outcomes included targeted cartilage proteomics, serum inflammation, and synovial fluid inflammation following an acute intra‐articular challenge with interleukin‐1β (IL‐1β). Compared to lean Zucker rats, obese Zucker rats developed more severe tibial osteophytes and focal cartilage lesions in the medial tibial plateau, with modest changes in proximal tibial epiphysis trabecular bone structure. In contrast, exogenous leptin treatment, which increased plasma leptin sixfold without altering body weight, caused mild generalized cartilage fibrillation and reduced Safranin O staining compared to vehicle‐treated animals. Leptin also significantly increased subchondral and trabecular bone volume and bone mineral density in the proximal tibia. Cartilage metabolic and antioxidant enzyme protein levels were substantially elevated with leptin deficiency and minimally suppressed with leptin treatment. In contrast, leptin treatment induced greater changes in systemic and local inflammatory mediators compared to leptin receptor deficiency, including reduced serum IL‐6 and increased synovial fluid IL‐1β. In conclusion, rat models that separately elevate leptin or body weight develop distinct OA‐associated phenotypes, revealing how obesity increases OA pathology through both leptin‐dependent and independent pathways. © 2023 The Authors. JBMR Plus published by Wiley Periodicals LLC on behalf of American Society for Bone and Mineral Research.
On the relative motion of the Earth and the luminiferous ether

THE discovery. of the aberration of light was soon followed by an explanation according to the emission theory. The effect was attributed to a simple composition of the velocity of light with the velocity of the earth in its orbit. The difficulties in this apparently sufficient explanation were overlooked until after an explanation on the undulatory theory of light was proposed. This new explanation was at first almost as simple as the former. But it failed to account for the fact proved by experiment that the aberration was unchanged when observations were made with a telescope filled with water. For if the tangent of the angle of aberration is the ratio of the velocity of the earth to the velocity of light, then, since the latter velocity in water is three-fourths its velocity ill a vacuum, the aberration observed with a water telescope should be fourthirds of its true value.t * This research was carried out with the aid of the Bache Fund. t It may be noticed that most writers admit the sufficiency ot the explanation according to the emission theory of light; while in fact the difficulty is even greater than according to the undulatory theory. For on the emission theory the velocity of light ! lnst be greater in the water telescope, and therefore the angle of aberration should be less; hence, in order to reduce it to its Lrue value, we must make the absurd hypothesis that the motion of the water in the telescope carries the ray of light in the opposite direction I
The Emergence of Spacetime from the Quantum in Three Steps

The paper presents a very simple and straight forward yet pure mathematical derivation of the structure of actual spacetime from quantum set theory. This is achieved by utilizing elements of the topological theory of cobordism and the Menger-Urysohn dimensional theory in conjunction with von Neumann-Connes dimensional function of Klein-Penrose modular holographic boundary of the E8E8 exceptional Lie group bulk of our universe. The final result is a lucid sharp mental picture, namely that the quantum wave is an empty set representing the surface, i.e. boundary of the zero set quantum particle and in turn quantum spacetime is simply the boundary or the surface of the quantum wave empty set. The essential difference of the quantum wave and quantum spacetime is that the wave is a simple empty set while spacetime is a multi-fractal type of infinitely many empty sets with increasing degrees of emptiness.
Real estate development, human capital, and economic growth in Kenya

The purpose of this study is to investigate the effect of real estate development and human capital on economic growth in Kenya by endogenizing the central bank rate and inflation as additional key variables that affect economic growth. This paper employs an autoregressive distributed lag (ARDL) model to analyze quarterly time series data spanning from the first quarter of 2009 to the fourth quarter of 2019. The results reveal that real estate development has a positive and significant impact on economic growth in the short run. The study also establishes a long-run relationship between real estate development, the central bank rate, inflation and economic growth. Specifically, the study establishes that inflation and the central bank rate are negatively and significantly associated with economic growth in the long run. This study makes significant progress in providing empirical evidence on the effect of real estate development, human capital, the central bank rate and inflation on economic growth in Kenya. Additionally, these findings are useful to all economies across the world, particularly developing countries such as Kenya. This study recommends the formulation of policies to encourage investment in real estate development and human capital, as they are crucial for economic growth in Kenya and other developing countries.
Antimicrobial susceptibility profile of Enterococcus species isolated from cows with clinical mastitis and from bulk milk tanks in Brazil

Vancomycin-resistant enterococci (VRE) have been reported as a major hazard to human and animal health, causing problems like clinical mastitis in dairy cattle and nosocomial infections in humans. The aim of this study was to determine the in vitro microbial susceptibility profile of enterococci isolated from dairy farms in São Paulo and Minas Gerais states, Brazil. A total of 310 samples of Enterococcus species from bovine mastitis (52) and bulk tanks (258) were analyzed. The sensibility profile was studied by the disk diffusion method, and the isolates intermediately resistant to vancomycin were submitted to the minimum inhibitory concentration (MIC) test. The enterococci also were classified according to their multiresistance profile. All isolates were sensitive to vancomycin. Most of the isolates from the bulk tanks were resistant to cephalexin (93.8%), novobiocin (98.8%), cefoxitin (91.9%) and oxacillin (91.9%), while those isolated from mastitis presented a high resistance to trimethoprim/sulfamethoxazole (84.7%), novobiocin (100%), cefoxitin (88.5%) and oxacillin (80.8%). All isolates were sensitive to vancomycin (VSE). The high prevalence of isolates resistant to multiple antimicrobials emphasizes the risks existing in the use of ineffective antibiotics.
Holographic Bell Inequality

The ER=EPR conjecture is proposed to resolve the black hole information paradox without introducing a firewall in the black hole. The conjecture implies that entanglement of the EPR pair, which is thought to be a quantum mechanical effect, can be captured by classical gravity through the ER bridge. Using Bell inequality as a sharp test of entanglement, we study a holographic model with an EPR pair at the boundary and an ER bridge in the bulk by using the Schwinger-Keldysh formalism. By revealing how Bell inequality is violated by gravity in the bulk, our study sheds light on the entanglement of the original ER=EPR, which, unlike holography, has both ER and EPR living in the same spacetime dimensions.
High-flow Nasal Cannula versus Conventional Ventilation in Laryngeal Surgery: A Systematic Review and Meta-analysis

High-flow nasal cannula (HFNC) is an emerging option for maintaining oxygenation in patients undergoing laryngeal surgery, as an alternative to traditional tracheal ventilation and jet ventilation (JV). However, the data on its safety and efficacy is sparse. This study aims to aggregate the current data and compares the use of HFNC with tracheal intubation and jet ventilation in adult patients undergoing laryngeal surgery. We searched PubMed, MEDLINE (Medical Literature Analysis and Retrieval System Online, or MEDLARS Online), Embase (Excerpta Medica Database), Google Scholar, Cochrane Library, and Web of Science. Both observational studies and prospective comparative studies were included. Risk of bias was appraised with the Cochrane Collaboration Risk of Bias in Non-Randomized Studies - of Interventions (ROBINS-I) or RoB2 tools and the Joanna Briggs Institute (JBI) Critical Appraisal Checklist for case series. Data were extracted and tabulated as a systematic review. Summary statistics were performed. Meta-analyses and trial sequential analyses of the comparative studies were performed. Forty-three studies (14 HFNC, 22 JV, and seven comparative studies) with 8064 patients were included. In the meta-analysis of comparative studies, the duration of surgery was significantly reduced in the THRIVE (Transnasal Humidified Rapid-Insufflation Ventilatory Exchange) group, but the number of desaturations, need for rescue intervention, and peak end-tidal CO2 were significantly increased compared to the conventional ventilation group. The evidence was of moderate certainty and there was no evidence of publication bias. In conclusion, HFNC may be as effective as tracheal intubation in oxygenation during laryngeal surgery in selected adult patients and reduces the duration of surgery but conventional ventilation with tracheal intubation may be safer. The safety of JV was comparable to HFNC.
A pr 2 01 9 Peer Effects in Random Consideration Sets ( Preliminary )

This paper develops a dynamic model of discrete choice that incorporates peer effects into consideration sets. We characterize equilibrium behavior and study the empirical content of the dynamic model we offer. In our set-up, the choices of friends act as exclusion restrictions in the stochastic variation of the subset of alternatives that each person considers at the moment of picking an option. They allow us to recover (from a sequence of observed choices) the ranking of preferences of each person, the attention mechanism, and the set of connections or nodes between the people in the network. The identification strategy we offer does not rely on the variation of the set of available options (or menus) which remain the same across all the observations. JEL codes: D83, O33