Miracle-dz/UniFAR-FTUs huggingface dataset:
Survival Rates of Dental Implants in Autogenous and Allogeneic Bone Blocks: A Systematic Review

Background and Objectives: Preliminary studies emphasize the similar performance of autogenous bone blocks (AUBBs) and allogeneic bone blocks (ALBBs) in pre-implant surgery; however, most of these studies include limited subjects or hold a low level of evidence. The purpose of this review is to test the hypothesis of indifferent implant survival rates (ISRs) in AUBB and ALBB and determine the impact of various material-, surgery- and patient-related confounders and predictors. Materials and Methods: The national library of medicine (MEDLINE), Excerpta Medica database (EMBASE) and Cochrane Central Register of Controlled Trials (CENTRAL) were screened for studies reporting the ISRs of implants placed in AUBB and ALBB with ≥10 participants followed for ≥12 months from January 1995 to November 2021. The review was conducted in accordance with Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. The risk of bias was assessed via several scoring tools, dependent on the study design. Means of sub-entities were presented as violin plots. Results: An electronic data search resulted in the identification of 9233 articles, of which 100 were included in the quantitative analysis. No significant difference (p = 0.54) was found between the ISR of AUBB (96.23 ± 5.27%; range: 75% to 100%; 2195 subjects, 6861 implants) and that of ALBB (97.66 ± 2.68%; range: 90.1% to 100%; 1202 subjects, 3434 implants). The ISR in AUBB was increased in blocks from intraoral as compared to extraoral donor sites (p = 0.0003), partially edentulous as compared to totally edentulous (p = 0.0002), as well as in patients younger than 45 as compared to those older (p = 0.044), cortical as compared to cortico-cancellous blocks (p = 0.005) and in delayed implantations within three months as compared to immediate implantations (p = 0.018). The ISR of ALBB was significantly increased in processed as compared to fresh-frozen ALBB (p = 0.004), but also in horizontal as compared to vertical augmentations (p = 0.009). Conclusions: The present findings widely emphasize the feasibility of achieving similar ISRs with AUBB and ALBB applied for pre-implant bone grafting. ISRs were negatively affected in sub-entities linked to more extensive augmentation procedures such as bone donor site and dentition status. The inclusion and pooling of literature with a low level of evidence, the absence of randomized controlled clinical trials (RCTs) comparing AUBB and ALBB and the limited count of comparative studies with short follow-ups increases the risk of bias and complicates data interpretation. Consequently, further long-term comparative studies are needed.
Silicon‐based passivating contacts: The TOPCon route

Passivating contacts based on poly‐Si/SiOx structures also known as TOPCon (tunnel oxide passivated contacts) have a great potential to improve the efficiency of crystalline silicon solar cells, resulting in more than 26% and 24% for laboratory and industrial cells, respectively. This publication gives an overview of the historical development of such contact structures which have started already in the 1980s and describes the current state‐of‐the‐art in laboratory and industry. In order to demonstrate the great variety of scientific and technological research, four different research topics are addressed in more detail: (i) the superior passivation quality of TOPCon structures made it necessary to re‐parametrize intrinsic recombination in silicon, (ii) the control of diffusion of dopants through the intermediate SiOx layer is essential to optimize passivation and transport properties, (iii) single‐sided deposition of the poly‐Si layer would reduce process complexity for industrial TOPCon cells, and (iv) silicon‐based tunnel junctions for perovskite–silicon tandem cells can be fabricated using the TOPCon technology.
A simple and efficient numerical method for nonlinear pulse propagation in N-core optical couplers

A set of N-dimension linear-coupled first-order differential equations were solved by a new method, which leads to a very simple iterative scheme. Based on the split-step Fourier technique, a simple and efficient algorithm was developed for analyzing pulse propagation in an N-core linear-coupled nonlinear coupler with the linear mismatch, loss, gain, higher order dispersion, and intermodal dispersion effect. It inherits the advantages of simplicity, flexibility, good accuracy, and relatively modest computing cost of the split-step Fourier method in single fiber.
The Clinical and Immunological Activity Depending on the Presence of Interferon γ in Primary Sjögren’s Syndrome—A Pilot Study

The upregulation of IFN pathways and their stimulated genes is associated with primary Sjögren’s syndrome (pSS). The recent studies also indicate the involvement of interferon γ (IFNγ) in the pathogenesis of pSS. The study aimed to assess the clinical and immunological activity depending on the concentration of IFNγ in the peripheral blood in pSS patients. Methods: The study group consisted of patients over 18 years of age with a confirmed diagnosis of pSS. Based on the collected data, disease activity was assessed using the EULAR Sjögren’s syndrome disease activity index (ESSDAI) and the EULAR Sjögren’s syndrome patient reported index (ESSPRI). Results: Among 40 pSS patients, 33 (82%) showed increased levels of IFNγ. The group with positive IFNγ was younger (43 years) than the group with negative IFNγ (57 years) (p < 0.05). In the positive IFNγ group, the time to diagnosis was shorter (p < 0.05). There was a difference in ESSDAI among patients with and without IFNγ (p < 0.05). There were no differences between the groups in ESSPRI and the presence of cryoglobulins, specific anti-SSA, and anti-SSB antibodies and in C3 and C4 hypocomplementemia. RF occurred in both groups with a similar frequency (p = 0.6), but in patients with IFNγ presence, significantly higher RF titers were observed (34.9 vs. 10.5; p < 0.05). Conclusion: In the group of patients with positive IFNγ, the mean value of RF and ESSDAI was higher. This group was also younger than patients with pSS without IFNγ.
Nonlinear HEMT Modeling Using Artificial Neural Network Technique

An improved nonlinear modeling technique for high electron mobility transistors (HEMT) based on the combination of the conventional equivalent circuit and artificial neural network (ANN) modeling techniques is presented. Effective initial values of the artificial neural network for each nonlinear element in HEMT model are evaluated from a semi-analytical parameter extraction technique. A multi-goal DC, S-parameter, and harmonic (DC/S/HB) training process has been formulated. Good agreement is obtained between the model and data of the DC, S parameter, and harmonic performance for a 200um gate width 0. 25μm PHEMT (FHX04LG) over a wide range of bias points.
Immune-Proteome Profiling in Classical Hodgkin Lymphoma Tumor Diagnostic Tissue

Simple Summary The proximity extension assay (PEA) method enables the detection of proteins in tissue lysates and plasma with high specificity and sensitivity. Knowledge regarding the immune proteome profile in classical Hodgkin Lymphoma (cHL) tumor microenvironment (TME) is critical in an era of emerging immunotherapies and precision medicine. This study identifies several important immune markers that distinguish cHL tissue from reactive lymph nodes and introduces new potential therapeutic targets in an era of personalized medicine. Abstract In classical Hodgkin Lymphoma (cHL), immunoediting via protein signaling is key to evading tumor surveillance. We aimed to identify immune-related proteins that distinguish diagnostic cHL tissues (=diagnostic tumor lysates, n = 27) from control tissues (reactive lymph node lysates, n = 30). Further, we correlated our findings with the proteome plasma profile between cHL patients (n = 26) and healthy controls (n = 27). We used the proximity extension assay (PEA) with the OlinkTM multiplex Immuno-Oncology panel, consisting of 92 proteins. Univariate, multivariate-adjusted analysis and Benjamini–Hochberg’s false discovery testing (=Padj) were performed to detect significant discrepancies. Proteins distinguishing cHL cases from controls were more numerous in plasma (30 proteins) than tissue (17 proteins), all Padj < 0.05. Eight of the identified proteins in cHL tissue (PD-L1, IL-6, CCL17, CCL3, IL-13, MMP12, TNFRS4, and LAG3) were elevated in both cHL tissues and cHL plasma compared with control samples. Six proteins distinguishing cHL tissues from controls tissues were significantly correlated to PD-L1 expression in cHL tissue (IL-6, MCP-2, CCL3, CCL4, GZMB, and IFN-gamma, all p ≤0.05). In conclusion, this study introduces a distinguishing proteomic profile in cHL tissue and potential immune-related markers of pathophysiological relevance.
Leveraging asynchronous speaking tasks to promote willingness and confidence to speak in Spanish: A qualitative study

This study describes the experiences of students in a flipped intermediate Spanish college class who used a video discussion digital tool to develop their confidence to speak in the foreign language. Students participated in a series of 10 speaking tasks designed based on the framework on technology-mediated tasks (Gonzalez-Lloret & Ortega, 2014) and the world-readiness standards for communicative performance of the American Council on the Teaching of Foreign Languages (2015). Through semi-structured interviews and reflection journals, students shared their learning accomplishments, unveiled their inner fears in speaking skills and detailed their journey in gaining confidence to speak in Spanish. Their experiences showed that willingness to communicate and self-efficacy are driving forces that, fostered in a brave learning environment, enable students to take risks and be creative with the language. The study also presents pedagogical implications regarding the design of technology-mediated tasks and the conditions of the learning environment that can foster or hinder students’ language oral communicative skills. Implications for practice or policy: Technology-mediated tasks should be designed based on a learner-centred approach and the affordances of the tool to promote communicative competence in foreign and second language learning. Technology-mediated tasks can promote the development of confidence to use the foreign and second language more spontaneously, while allowing students to fail without being judged or penalised. Technology-mediated tasks can give students some control over their own learning process, facilitating opportunities for self-monitoring to gain confidence in speaking in the foreign or second language.
Molecular identification and genetic relationships among Alcea (Malvaceae) species by ISSR Markers: A high value medicinal plant

Alcea L. is one of the largest genera of Malvaceae family with nearly 70 species worldwide mainly distributed in SW Asia. According to the latest revision of the family, it is represented by 34 species in the Flora of Iran, among them, 15 species are endemic. It is tough to accurate germplasm/ plant recognition by using morphological characteristics because of its propagation, growing and using. We conducted a molecular data analysis on these plant species due to their importance. We examined 156 plants from 14 species in 16 regions that were selected randomly for this investigation. It has been 119 polymorphic bands (94.33%) were resulted from 128 bands of 10 primers in amplification of genomic DNA. ISSR primers have a great capacity to detect polymorphic loci among Alcea species, as evidenced by the high average PIC and MI values found. The genetic similarity of 14 species was calculated and ranged between 0.635 to 0.990. Inter-Simple sequence repeats (ISSR) markers research revealed that Alcea tarica Pakravan & Ghahreman and Alcea kopetdaghensis lljin had the least similarity, while Alcea semnanica Pakravan and Alcea mazandaranica Pakravan & Ghahreman had the most. The current study attempts to answer three questions: 1) can ISSR markers identify Alcea species? 2) what is the genetic structure of these taxa in Iran? and 3) what is the inter-relationship between these taxa? The current study discovered that ISSR markers can be used to identify species.
Simple wideband CIC compensator

A simple design for wideband compensation of a cascaded-integrator-comb (CIC) decimation filter is presented. The proposed multiplierless linear phase finite impulse response compensator works at a low sampling rate and requires only three additions/subtractions. The structure of the filter is independent of the decimation factor and the number of the cascaded CIC filters K. However, the proposed filter requires K or K−1 stages, depending on the parameter K of the CIC filter.
The Dark Tetrad and aesthetic preferences: The role of the dark side of personality in the aesthetic preference for paintings

The role of so-called normal and dark personality traits in everyday preferences, interests, and choices is visible in different domains of life. However, a small number of studies have dealt with individual differences in dark personality traits and aesthetic preferences. The domain of dark personality traits is in recent studies generally conceptualized as the Dark Tetrad — comprised of Machiavellianism, narcissism, psychopathy, and sadism. Thus, the aim of this research was to examine the relationship between the Dark Tetrad and visual aesthetic preferences. The sample consisted of 170 participants (Mage = 29.09, SDage = 10.66; 77.1 % females). Participants completed the Short Dark Triad and the Varieties of Sadistic Tendencies questionnaires, and also rated their familiarity and preference for 15 paintings with five different types of motives (religious, abstract, oriental, violence, and landscape). It was shown, based on looking at zero-order correlations that only narcissism positively correlates with the preference for paintings with violent motives. Also, a series of regression analyses were performed, which showed that the only significant regression model is the one that reflects the role of reduced psychopathy in the preference for religious motives. The first finding can be explained on the basis of stable findings on the relationship between narcissism and aggression, and also narcissism and violence. The second finding can be interpreted in the context that general religiosity has previously been shown to be negatively associated with psychopathy. It can be concluded that dark personality traits are one of the factors that affect aesthetic preferences.
Design and Implementation of a Compact Master-Slave Robotic System with Force Feedback and Energy Recycling*

Master-slave control is becoming increasingly popular in the development of robotic systems which can provide rehabilitation training for hemiplegic patients with a unilaterally disabled limb. However, the system structures and control strategies of existent master-slave systems are always complex. An innovative master-slave system implementing force feedback and motion tracking for a rehabilitation robot is presented in this paper. The system consists of two identical motors with a wired connection, and the two motors are located at the master and slave manipulator sites respectively. The slave motor tracks the motion of the master motor directly driven by a patient. As well, the interaction force produced at the slave site is fed back to the patient. Therefore, the impaired limb driven by the slave motor can imitate the motion of the healthy limb controlling the master motor, and the patient can regulate the control force of the healthy limb properly according to the force sensation. The force sensing and motion tracking are achieved simultaneously with neither force sensors nor sophisticated control algorithms. The system is characterized by simple structure, bidirectional controllability, energy recycling, and force feedback without a force sensor. Test experiments on a prototype were conducted, and the results appraise the advantages of the system and demonstrate the feasibility of the proposed control scheme for a rehabilitation robot.
www.clinicalcases.eu Archive of Clinical Cases

Recurrent vulvar squamous cell carcinoma with multiple site metastases is a rare entity – (up to 14.2% of the total number of recurrences), with a poor prognosis (only 15% of the patients alive at 5 years). Due to its “hard to find” character, there are no standardized guidelines available and the treatment is extrapolated from advanced cervical carcinoma, anal carcinoma and other squamous cell carcinomas. Immunotherapy has shown some positive results in vulvar carcinoma with PD-L1 positive, high TMB, high MSI or with MMR deficiency. An alternative for selected cases without therapeutic resources could be the HPV vaccine. We present the case of a 64-year-old woman diagnosed in 2014 with vulvar squamous cell carcinoma stage II for which she underwent radical vulvectomy with bilateral inguinal lymphadenectomy followed by external radiotherapy. In 2019 she developed local recurrence associated with lung, pleural, lymph nodes and subcutaneous metastasis, treated with three lines of chemotherapy: paclitaxel/carboplatin followed by cisplatin/5-fluorouracil and carboplatin/gemcitabine. The patient’s general health status altered progressively, and she died after the 4 cycle of carboplatin/gemcitabine. This case’s management could be a starting point for the vulvar carcinoma cases where the standard therapeutical options do not represent a choice anymore, providing the necessary example on how to approach it.
Genome-wide analysis of horizontal transfer in non-model wild species from a natural ecosystem reveals new insights into genetic exchange in plants

Background Horizontal transfer (HT) refers to the exchange of genetic material between divergent species by mechanisms other than reproduction. In recent years, several studies have demonstrated HTs in eukaryotes, particularly in the context of parasitic relationships and in model species. However, very little is known about HT in natural ecosystems, especially those involving non-parasitic wild species, and the nature of the ecological relationships that promote these HTs. Results In this work, we conducted a pilot study investigating HTs by sequencing the genomes of 17 wild non-model species from a natural ecosystem, the Massane forest, located in southern France. To this end, we developed a new computational pipeline called INTERCHANGE that is able to characterize HTs at the whole genome level without prior annotation and directly in the raw sequencing reads. Using this pipeline, we identified 12 HT events, half of which occurred between lianas and trees. We found that mainly low copy number LTRs retrotransposons from the Copia superfamily were transferred between these wild plant species, especially those of the Ivan and Ale lineages. Conclusion This study revealed a possible new route for HTs between non-parasitic plants and provides new insights into the genomic characteristics of horizontally transferred DNA in plant genomes.
China’s ecosystem services planning: will Shanghai lead the way? A case study from the Baoshan district (Shanghai)

Ecosystem services (ES) are a fundamental component of well-being and sustainable urban development with tremendous potential to enhance urban planning. Recently, several studies have evaluated the environmental performance of urban plans using the ES approach. To strengthen this science-policy integration, it is still necessary to perform ES assessments within the urban planning practice as well as to collect empirical evidence on the impacts of envisioned planning measures on the supply of ES in urban environments across the world. In this research, we analyzed the state-of-the-art of China’s new environmental governance, which aims to change China’s land use policy and particularly the role of Green Infrastructure (GI) regarding urban planning and ES. We focused on the Shanghai Baoshan district Master Plan as a case study, and analyzed it under the lenses of the supply of ES using the matrix approach. We ascertained the supply of ES as delineated in the ecological network plan for 2035, and developed an evaluation framework based on CICES v5.1 and two expert workshops. Our approach used an integrated preliminary ES-assessment, and evaluated the consequences for the supply of ES in Baoshan district, which is adaptable to varying urban geographies. The results of our assessment show that, if realized as planned, the district will increase the overall supply of ES, especially regulating and cultural services, that play an important role within GI on the urban level. In general, the land use plans should include fine-grained information within building blocks to allow for even better assessing of the spatial structure of the supply of ES
THE INFLUENCE OF LIGHT QUALITY IN THE in vitro CULTIVATION OF Cattleya crispata

ABSTRACT: Micropropagation technique is a valuable alternative for high quality genetic preservation of endemic species such as the orchid Cattleya crispata from “Campo Rupestre Ferruginoso”. This study aims to evaluate the influence of light quality on in vitro multiplication and elongation phases, offering new insights on the limiting factors of C. crispata. Seeds extracted from capsules were used for inoculation in the culture medium. Four light sources were evaluated for in vitro culture, namely: fluorescent lamp, white LEDs, red LEDs and red/blue LEDs. Data about the number of shoots, shoot length, shooting vigor and pigment content were assessed at 90 days of in vitro culture. Based on the recorded results, white LEDs are the most suitable ones for in vitro multiplication and elongation phases of C. crispata. It offers higher quality for seedling production and increases the chances of genetic conservation of the species. Keywords: ‘Campo Rupestre Ferruginoso’; in vitro propagation; wavelength; LEDs.
The impact of prior experience on shopping behaviors

This study explores the effects of prior experience on determinants of repurchase intention and antecedents of perceived uncertainty in an online shopping environment. The study proposes a model which integrates perceived uncertainty, trust, and technology acceptance model (TAM). Structure Equation Modeling (SEM) is used to find out the difference between low- and high-experienced online shoppers. The results indicate that trust in an e-vendor vis-à-vis the TAM constructs has consistent effects on all experienced online shoppers. However, perceived uncertainty affects only the low-experienced online shoppers’ trust in an e-vendor. The data also shows that the sources of perceived uncertainty, which is classified into relationship uncertainty and environmental uncertainty, are different for the low- and high-experienced online shoppers. Our findings provide the managers of e-vendors with the information about the difference in the online shoppers’ prior experiences.