Miracle-dz/UniFAR-FTUs huggingface dataset:
Images of entrepreneurship: divergent national constructions of what it is to ‘do’ entrepreneurship

ABSTRACT In this research note, we further Alistair R. Anderson’s argument that an atomized view of entrepreneurship as an economic function provides limited understanding of what it is to actually do entrepreneurship. We take the stance that entrepreneurship, as a process, is born of social context. What it is to be and what it is to do entrepreneurship is informed directly by the images of entrepreneurship accepted in society. To better understand the implications of this, we access the ways in which entrepreneurship is imagined in three ostensibly similar country settings: UK, Italy and Finland. We analyse the social discourses surrounding the concept from a sample of enterprise students across the three areas. Importantly, these participants are not entrepreneurs in their own right, but are considered interested stakeholders, in that the meaning they ascribe to entrepreneurship will partly inform their future approaches to it. We contrast data from 15 semi-structured interviews with policy commentary and measurable outcomes and find nuanced differences in how entrepreneurship is perceived and enacted. The implications of our findings encourage a more holistic approach to the study of entrepreneurship, avoiding the self-affirming dogma of the purely economic or purely constructionist.
Apocynin Attenuates Diabetes-Induced Skeletal Muscle Dysfunction by Mitigating ROS Generation and Boosting Antioxidant Defenses in Fast-Twitch and Slow-Twitch Muscles

In response to diabetes mellitus, skeletal muscle is negatively affected, as is evident by reduced contractile force production, increased muscle fatigability, and increased levels of oxidative stress biomarkers. Apocynin is a widely used NADPH oxidase inhibitor, with antioxidant and anti-inflammatory potential. It has been effective for amelioration of a variety of disorders, including diabetic complications. Therefore, the present study was conducted to evaluate the effects and action mechanisms of apocynin in slow- and fast-twitch diabetic rat muscles. Male Wistar rats were rendered diabetic by applying intraperitoneally a single dose of streptozotocin (45 mg/kg). Apocynin treatment (3 mg/kg/day) was administered over 8 weeks. Fasting blood glucose (FBG), insulin tolerance and body weight gain were measured. Both slow (soleus) and fast (extensor digitorum longus, EDL) skeletal muscles were used for muscle function evaluation, oxidative stress markers, and evaluating gene expression using qRT-PCR. Treatment with apocynin significantly reduced FBG levels and enhanced insulin tolerance. Apocynin also prevented muscle contractile dysfunction in EDL muscle but had no significant effect on this parameter in soleus muscles. However, in both types of muscles, apocynin mitigated the oxidative stress by decreasing ROS levels and increasing total glutathione levels and redox state. Concomitantly, apocynin also statistically enhanced Nrf-2 and GLU4 mRNA expression and downregulated NOX2, NOX4, and NF-κB mRNA. Collectively, apocynin exhibits properties myoprotective in diabetic animals. These findings indicate that apocynin predominantly acts as an antioxidant in fast-twitch and slow-twitch muscles but has differential impact on contractile function.
Outcome Analysis in Elective Electrical Cardioversion of Atrial Fibrillation Patients: Development and Validation of a Machine Learning Prognostic Model

Background: The integrated approach to electrical cardioversion (EC) in atrial fibrillation (AF) is complex; candidates can resolve spontaneously while waiting for EC, and post-cardioversion recurrence is high. Thus, it is especially interesting to avoid the programming of EC in patients who would restore sinus rhythm (SR) spontaneously or present early recurrence. We have analyzed the whole elective EC of the AF process using machine-learning (ML) in order to enable a more realistic and detailed simulation of the patient flow for decision making purposes. Methods: The dataset consisted of electronic health records (EHRs) from 429 consecutive AF patients referred for EC. For analysis of the patient outcome, we considered five pathways according to restoring and maintaining SR: (i) spontaneous SR restoration, (ii) pharmacologic-cardioversion, (iii) direct-current cardioversion, (iv) 6-month AF recurrence, and (v) 6-month rhythm control. We applied ML classifiers for predicting outcomes at each pathway and compared them with the CHA2DS2-VASc and HATCH scores. Results: With the exception of pathway (iii), all ML models achieved improvements in comparison with CHA2DS2-VASc or HATCH scores (p < 0.01). Compared to the most competitive score, the area under the ROC curve (AUC-ROC) was: 0.80 vs. 0.66 for predicting (i); 0.71 vs. 0.55 for (ii); 0.64 vs. 0.52 for (iv); and 0.66 vs. 0.51 for (v). For a threshold considered optimal, the empirical net reclassification index was: +7.8%, +47.2%, +28.2%, and +34.3% in favor of our ML models for predicting outcomes for pathways (i), (ii), (iv), and (v), respectively. As an example tool of generalizability of ML models, we deployed our algorithms in an open-source calculator, where the model would personalize predictions. Conclusions: An ML model improves the accuracy of restoring and maintaining SR predictions over current discriminators. The proposed approach enables a detailed simulation of the patient flow through personalized predictions.
Apparent diffusion coefficient of piriform cortex and seizure outcome in mesial temporal lobe epilepsy after MR-guided laser interstitial thermal therapy: a single-institution experience.

OBJECTIVE Piriform cortex (PC) is one of the critical structures in the epileptogenesis of mesial temporal lobe epilepsy (mTLE), but its role is poorly understood. The authors examined the utility of apparent diffusion coefficient (ADC; an MR-based marker of tissue pathology) of the PC as a predictor of seizure outcome in patients with mTLE undergoing MR-guided laser interstitial thermal therapy (MRgLITT). METHODS A total of 33 patients diagnosed with mTLE who underwent MRgLITT at the authors' institution were included in the study. The 6-month postoperative seizure outcomes were classified using the International League Against Epilepsy (ILAE) system as good (complete seizure freedom, ILAE class I) and poor (seizure present, ILAE classes II-VI). The PC and ablation volumes were manually segmented from both the preoperative and intraoperative MRI sequences, respectively. The mean ADC intensities of 1) preablation PC; 2) total ablation volume; 3) ablated portion of PC; and 4) postablation residual PC were calculated and compared between good and poor outcome groups. Additionally, the preoperative PC volumes and proportion of PC volume ablated were examined and compared between the subjects in the two outcome groups. RESULTS The mean age at surgery was 36.5 ± 3.0 years, and the mean follow-up duration was 1.9 ± 0.2 years. Thirteen patients (39.4%) had a good outcome. The proportion of PC ablated was significantly associated with seizure outcome (10.16 vs 3.30, p < 0.05). After accounting for the variability in diffusion tensor imaging acquisition parameters, patients with good outcome had a significantly higher mean ADC of the preablation PC (0.3770 vs -0.0108, p < 0.05) and the postoperative residual PC (0.4197 vs 0.0309, p < 0.05) regions compared to those with poor outcomes. No significant differences in ADC of the ablated portion of PC were observed (0.2758 vs -0.4628, p = 0.12) after performing multivariate analysis. CONCLUSIONS A higher proportion of PC ablated was associated with complete seizure freedom. Preoperative and postoperative residual ADC measures of PC were significantly higher in the good seizure outcome group in patients with mTLE who underwent MRgLITT, suggesting that ADC analysis can assist with postablation outcome prediction and patient stratification.
Doppler Changes in Pre-Eclampsia

Background: Preeclampsia is a multisystem disorder of pregnancy defined by the combination of new-onset hyperten- sion and proteinuria that contribute substantially to perinatal morbidity and mortality worldwide. Aim of Study: This study was sought to use Doppler ultrasound to assess the hemodynamic changes in the uterine, umbilical, and middle cerebral arteries, among pregnant women with and without Preeclampsia. Patients and Methods: A prospective Observational study of pregnant women who recruited from Department of Obstetrics and Gynecology, Aswan University Hospitals during September 2019 until March 2020, and may be extended if needed. Results: There is statistically significant difference between groups as regard to umbilical artery (RI and abnormality), middle cerebral artery (PI, RI and abnormality) and uterine artery (PI, RI, abnormality and notch) but there is no statistically significant difference between groups as regard to umbilical artery PI ( p -value=0.117). Conclusion: This study demonstrated that Doppler US can reveal the underlying hemodynamic repercussion in the maternal-fetal circulation and thus can be used to determine the proper level of antenatal care in pregnant women. Umbilical artery and Middle cerebral arteries indices were more altered in Preeclampsia.
Response of yield, growth traits, and leaf nutrients of garden cress to deficit saline irrigation waters

abstract Food sustainability is continuously restricted by water shortage and poor water quality in water-scarce regions. In this study, a pot experiment was carried out under rain shelter conditions to quantify the impact of the different levels of water salinity on the yield, leaf nutrients, and growth traits of garden cress under different water-deficit levels. Twelve treatments included three water-deficit (WD) levels (I0, I1, and I2 indicating 100, 80, and 60% of field capacity, respectively) in combination with four saline irrigation water levels (IWS) (S1, S2, S3, and S4, indicating 0.38, 2, 4, and 8 dSm−1, respectively). Also, multiple linear regression analysis was performed to predict garden cress yield using WD, IWS, and soil salinity (ECe) parameters in different combinations. The results showed that yield, leaf area, stomata, chlorophyll content, leaf Ca2+, K+, K+/Na+, and Ca2+/Na+ markedly decreased under water deficit and water salinity interaction. The highest and lowest ECe values were observed at the I2S4 (8.67 dSm−1) and I0S1 (0.88 dSm−1) treatments. The highest yield was found at I0S1 (166.1 g pot−1), and it was 49.8% and 62.0% higher than I1S4 and I2S4 treatments. The developed models have R2 larger than 0.92, showing that they could provide a valuable tool for evaluating and estimating the garden cress productivity under different WD and IWS conditions. Finally, we conclude that WD (80% of FC or lower) combined with a higher IWS of 0.38 dSm−1 is not recommended for irrigating garden cress, which will cause considerable yield and commercial quality reduction of garden cress plants.
Estimation of design load and distribution pattern for wooden classroom chairs in use at secondary schools in Ibadan, Nigeria

The absence of an established design load constitutes a challenge to the engineering design of classroom furniture. This study developed a methodology for estimating design loads for single user (SU) and multiple user (MU) wooden classroom chair and desk combinations offered to secondary school students in Ibadan, Oyo State, Nigeria. Service load distribution patterns for the chair and desk members in normal, backward and front-reclining sitting postures were determined for 15 girls and 15 boys using bathroom scales. A T-test was used to compare the significance of the means of the proportions of users’ weights transferred to the chair and the floor. Design loads were 1 kN (SU) and 2.7 kN (MU) for chair and desk configurations, respectively. Each SU and MU leg should be designed to support 35% and 40% of the service loads, respectively. Gender, sitting postures, and chair and desk designs influenced load distribution patterns significantly.
Effect of Nanofillers on Mechanical and Water Absorption Properties of Alkaline Treated Jute Fiber Reinforced Epoxy Bio Nanocomposites

ABSTRACT Natural fiber composites (NFCs) are gaining popularity in various technical sectors due to their environmental friendliness and low cost. In this study, alumina and magnesia were employed as nanofillers in various compositions of alkaline-treated and untreated jute fiber reinforced epoxy bio nanocomposites (BNCs). The synergetic effect of surface treatment and nanofillers was investigated in terms of mechanical properties (compression and interlaminar shear), water absorption behavior, and morphology of composites. Significant improvements in compressive and interlaminar shear strengths were reported, as well as a substantial decrease in the proportion of water absorbed. The optimal nanofiller concentration was observed at 3% in both alkaline-treated and untreated jute fiber-reinforced epoxy BNCs. The results demonstrate that nanofillers combined with surface treatment can significantly improve the strength and water absorption properties of jute fiber reinforced epoxy BNCs.
‘Comparison and correlation of the maxillary sinus dimensions in various craniofacial patterns: A CBCT Study’

Background: To compare and correlate the maxillary sinus dimensions and basal bone height among various facial patterns using CBCT for advanced diagnosis and treatment planning in Orthodontics. Methods: 66 CBCT images within age group of 18-30 years were divided into horizontal (Group 1), average (Group 2) and vertical (Group 3) facial growth patterns. Maxillary sinus dimensions were compared and correlated in all three groups. The sinus height and basal bone height were recorded at 3 locations-between 1 st premolar and 2 nd premolar (PM1-PM2), between 2 nd premolar and 1 st Molar (PM2-M1) and between 1 st and 2 nd molar (M1-M2). Results: Overall reduction in sinus height and significantly reduced sinus volume was seen in Group-1. Longest maxillary sinus height in M1-M2 region and shortest in PM1-PM2 region was seen in Group-3. The basal bone height in PM1-PM2 region was significantly longer in Group-3 than in Group-1(p<.05). Shortest basal bone height in M1-M2 region was seen in Group-3. A significant negative correlation was seen between the maxillary sinus height and the basal bone height in Group-1 and Group-3(p<.05). Conclusion: There is a correlation between the maxillary sinus height and basal bone height with that of facial pattern which needs to be considered during orthodontic treatment planning and while carrying out facial growth modification procedures in younger patients.
Transcriptional Contribution of Transposable Elements in Relation to Salinity Conditions in Teleosts and Silencing Mechanisms Involved

Fish are an interesting taxon comprising species adapted to a wide range of environments. In this work, we analyzed the transcriptional contribution of transposable elements (TEs) in the gill transcriptomes of three fish species exposed to different salinity conditions. We considered the giant marbled eel Anguilla marmorata and the chum salmon Oncorhynchus keta, both diadromous, and the marine medaka Oryzias melastigma, an euryhaline organism sensu stricto. Our analyses revealed an interesting activity of TEs in the case of juvenile eels, commonly adapted to salty water, when exposed to brackish and freshwater conditions. Moreover, the expression assessment of genes involved in TE silencing mechanisms (six in heterochromatin formation, fourteen known to be part of the nucleosome remodeling deacetylase (NuRD) complex, and four of the Argonaute subfamily) unveiled that they are active. Finally, our results evidenced for the first time a krüppel-associated box (KRAB)-like domain specific to actinopterygians that, together with TRIM33, might allow the functioning of NuRD complex also in fish species. The possible interaction between these two proteins was supported by structural prediction analyses.
Technology trends of silicon-on-insulator-its advantages and problems to be solved

Recent progress in SOI technology is reviewed and problems which need be solved are discussed. Emphasis is placed on the substrate floating effect, for which the bandgap engineering method is proposed for the first time. It is demonstrated that Si-Ge formation in the source region can improve the drain breakdown voltage significantly. <<ETX>>
The transition from academy to professional football: an examination of factors influencing players' progression when encountering and adapting to a first team context

Based on the transitional phases outlined in Jones et al. (2014), the main objective of this study was to examine factors influencing players’ progression when encountering and adapting to a first team context in the transition to professional football. Using a hierarchical content analysis, transcribed semi-structured interviews with eight elite development coaches in two professional football clubs was inductively and deductively analyzed. The analysis generated six higher-order categories influencing the progression in the encounter and adaption phase of the transition. These were; adaptability, survival strength, practice behavior, social competence, nature of elite football and relationship between academy and first team. Collectively, these higher-order categories illustrate the multifaceted and complex nature of the academy-to-firstteam transition when encountering and adapting to the context of a professional football club. Following this, practical implications and recommendations for future research are discussed. Keywords; career transition, professional football, talent, junior-to-senior
Analysis of Intestinal Microbial Diversity of Four Species of Grasshoppers and Determination of Cellulose Digestibility

Simple Summary Grasshoppers are typical phytophagous pests, which prefer eating monocotyledons with more cellulose and hemicellulose. Due to its large appetite and high utilization rate, the intestinal contents of grasshoppers have the potential to be developed into a bioreactor, which can be applied to improve straw utilization efficiency in the future. The digestive tract of grasshoppers is a complex ecosystem, inhabited by a large number of microorganisms. The existence of these microorganisms enables grasshoppers to have high decomposition and utilization of plant fibers. However, there are few reports on the microflora structure and diversity of the digestive tract of grasshoppers. In this study, the diversity of symbiotic bacteria in the intestinal tract of four species of grasshoppers, namely Acrida cinerea, Trilophidia annulata, Atractomorpha sinensis and Sphingonotus mongolicus, was studied by using the method of constructing a 16S rRNA gene library and Illumina Miseq sequencing technology. At the same time, the digestibility of cellulose and hemicellulose of the four species of grasshoppers were determined and the relationship between digestibility and intestinal microbial diversity was analyzed. This study provided basic data for the development of the digestible bioreactor of cellulose and hemicellulose, which may provide a new idea for degrading straw. Abstract Grasshoppers (Insecta, Orthoptera, Acridoidea) are a large group of agricultural and animal husbandry pests. They have a large food intake with high utilization of plants fibers. However, the composition of the grasshopper gut microbial community, especially the relationship between gut microbial community and cellulose digestibility, remains unclear. In this research, 16S rRNA gene sequences were used to determine the intestinal microbial diversity of Acrida cinerea, Trilophidia annulata, Atractomorpha sinensis and Sphingonotus mongolicus, and Spearman correlation analysis was performed between the intestinal microbes of grasshoppers and the digestibility of cellulose and hemicellulose. The results showed that Proteobacteria was the dominant phylum and Klebsiella was the dominant genus in the guts of the four species of grasshoppers; there was no significant difference in the species composition of the gut microbes of the four species of grasshoppers. Spearman correlation analysis showed that Brevibacterium and Stenotrophomonas were significantly correlated with cellulose digestibility. Brevibacterium, Clavibacter, Microbacterium and Stenotrophomonas were significantly associated with hemicellulose digestibility. Our results confirmed that the gut microbes of grasshoppers were correlated with the digestibility of cellulose and hemicellulose, and indicated that grasshoppers may have the potential to develop into bioreactors, which can be applied to improve straw utilization efficiency in the future.
Input and competing grammars in L2 syntax

Grammar competition has been proposed as a model for second language (L2) acquisition. Variational Learning provides a framework within which to investigate the idea of grammar competition as the model requires a marriage of quantitative properties of the input with Universal Grammar. A diachronic variational model of grammar competition is extended to second language acquisition (L2A) to explore verb-second word order optionality in L2 English. Patterns of L1-German–L2-English word order acquisition are reviewed in light of a study of classroom discourse as input to first language (L1) German speakers. A variational model of word order patterns in the input identifies differences in patterns of word order optionality, which may contribute to the trajectory of acquisition identified for L2 English.
Development of the Hedonic Overeating–Questionnaire (HEDO–Q)

Addictive-like eating is prevalent, but a clear conceptualization and operationalization outside of an addiction framework is lacking. By adopting a biopsychological framework of food reward, this study sought to develop and evaluate a brief self-report questionnaire for the trait assessment of hedonic overeating and dyscontrol. Items in the Hedonic Overeating–Questionnaire (HEDO–Q) were constructed following a rational approach and psychometrically evaluated in a large random sample from the German population (N = 2531). A confirmatory factor analysis supported the unidimensional nature of the six-item HEDO–Q with the three postulated components of wanting, liking, and dyscontrol. Psychometric properties were favorable with good corrected item-total correlations, acceptable item difficulty and homogeneity, and high internal consistency. Population norms were provided. The HEDO–Q revealed strict measurement invariance for sex and partial invariance for age and weight status. Discriminant validity was demonstrated in distinguishing participants with versus without eating disturbances or obesity. Associations with the established measures of eating disorder and general psychopathology supported the convergent and divergent validity of the HEDO–Q. This first evaluation indicates good psychometric properties of the HEDO–Q in the general population. Future validation work is warranted on the HEDO–Q’s stability, sensitivity to change, and predictive and construct validity.
The Characterization of Liquefied Petroleum Gas (LPG) Using a Modified Bunsen Burner

The equivalence ratio ranges were found between 22.77 and 42.93 for the Saudi LPG/air mixture using a traditional Bunsen burner. An operation problem was found with a traditional Bunsen burner for the Saudi LPG/air mixture, especially in a lean mixture. Therefore, a Bunsen burner was successfully modified to overcome the limits of operation with different mixtures of Saudi LPG/air and a stable flame was obtained. The equivalence ratio ranges were found between 0.68 and 1.30 using the modified Bunsen burner. A premixed flame was used for the modified Bunsen burner. A MATLAB algorithm was successfully applied to flame image processing and measurement of laminar burning velocity. The laminar burning velocity was determined to be approximately 35 ± 0.91 cm/s under stoichiometric conditions using the modified Bunsen burner for the Saudi LPG/air mixture. The half-cone angle of the flame was found to be 16.20 ± 0.76°. The minimum flame height was observed to be 21.50 ± 0.22 mm above the Bunsen burner exit.