Miracle-dz/UniFAR-FTUs huggingface dataset:
New current modified Schrödinger equations

New current modified Schrodinger equations are derived suited to study waves on both potential and non–potential inhomogeneous currents. Split–step schemes of first, second, and fourth order are discussed. Different results are presented regarding the current terms and the model setup. This paper mainly serve as background information for Hjelmervik & Trulsen (2009), but the current modified Schrodinger equations and model setup presented here are expected to have an even larger range of application possibilities.
Biomedical Multimedia Encryption by Fractional-Order Meixner Polynomials Map and Quaternion Fractional-Order Meixner Moments

Chaotic systems are widely used in signal and image encryption schemes. Therefore, the design of new chaotic systems is always useful for improving the performance of encryption schemes in terms of security. In this work, we first demonstrate the chaotic behavior of fractional order Meixner polynomials (FrMPs) for introducing a new two-dimensional (2D) chaotic system called FrMPs map. This system is very sensitive to any variation by 10−15 of its control parameters ( $\mu \textrm {and}\beta$ ). Next, we use FrMPs to introduce a new type of orthogonal transforms called quaternion fractional order Meixner moments (QFrMMs). The latter generalize the existing fractional order Meixner moments. To demonstrate the relevance of the proposed FrMPs map and QFrMMs in the field of signal and image processing, they are applied in the development of a new encryption scheme. The main advantage of this scheme is its applicability to the encryption of different types of biomedical data such as multi-biomedical signals, multiple grayscale medical images, color medical image, and grayscale medical image. Several simulation analysis (visual, histogram, runtime, correlation, robustness, etc.) are conducted to verify the efficiency of the proposed scheme. Simulation and comparison results confirm that our encryption method is effective in terms of high security level, high quality of the decrypted information, strong resistance to different types of attacks, etc. These findings support the suitability of the proposed scheme for the secure exchange of biomedical multimedia via a public communication channel.
Comparison of Genomic Profiling Data with Clinical Parameters: Implications for Breast Cancer Prognosis

Simple Summary Around 20 years ago, genomic profiling of breast carcinomas identified tumor subtypes with clinical implications and opened the door for a better understanding of breast cancer biology. The commercialization of multigene tests had a significant impact on clinical practice, and yet, controversy exists as to which methodology is best to inform the choice of therapy and existing recommendations are inconsistent and often driven by cost-effectiveness. Here we report data from a cohort of breast cancer patients in which pathological and molecular subtyping are directly compared in a clinical setting. The findings show that some patients with genomic low-risk tumors could receive unnecessary systemic therapy if only following the classical clinical parameters, while others could remain under-treated. This study suggests that to design precise treatment regimens for patients with early breast cancer, the conventional clinicopathological classification should be complemented with the robust prognostic information provided by molecular subtyping. Abstract Precise prognosis is crucial for selection of adjuvant therapy in breast cancer. Molecular subtyping is increasingly used to complement immunohistochemical and pathological classification and to predict recurrence. This study compares both outcomes in a clinical setting. Molecular subtyping (MammaPrint®, TargetPrint®, and BluePrint®) and pathological classification data were compared in a cohort of 143 breast cancer patients. High risk clinical factors were defined by a value of the proliferation factor Ki67 equal or higher than 14% and/or high histological grade. The results from molecular classification were considered as reference. Core needle biopsies were found to be comparable to surgery samples for molecular classification. Discrepancies were found between molecular and pathological subtyping of the samples, including misclassification of HER2-positive tumors and the identification of a significant percentage of genomic high risk T1N0 tumors. In addition, 20% of clinical low-risk tumors showed genomic high risk, while clinical high-risk samples included 42% of cases with genomic low risk. According to pathological subtyping, a considerable number of breast cancer patients would not receive the appropriate systemic therapy. Our findings support the need to determine the molecular subtype of invasive breast tumors to improve breast cancer management.
An insight into the invasion of breast ductal carcinoma in situ based on clinical, pathological and hematological data

Background Ductal carcinoma in situ (DCIS) has become a non-negligible part of breast cancers owing to the greatly increased incidence. While its natural history was not fully elucidated, which is the reason for current controversies in clinical treatment. Exploration of this issue from a clinical perspective is meaningful. Methods Medical records of 389 patients diagnosed with DCIS or DCIS with invasive ductal carcinoma (IDC) were reviewed. All of them received appropriate medical care in our center. All 324 patients in training cohort were divided into invasion and non-invasion groups based on pathology. Differences in DCIS immunohistochemical markers and hematological indicators between them were analyzed. In the invasion group, differences between DCIS and matched IDC were compared to explore changes in the tumor heterogeneity during invasion. Conclusions are validated in the validation cohort of 65 patients. Results Patients in invasion and non-invasion groups were balanced in baseline characteristics and no statistically significant differences were noticed for DCIS immunohistochemical markers. For hematological indicators, high expression of platelet >291.50) (odds ratio, 2.46; CI [1.35–4.46]; p = 0.003) and SII (>347.20) (odds ratio, 2.54; CI [1.56–4.12]; p < 0.001) were established as independent predictors for invasion by logistic analysis and were validated in the validation cohort. Ki-67 of IDC was significantly higher than that of matched DCIS (p < 0.001). HER2 expression and histological grade of DCIS were separately linearly related to those of IDC. Conclusion The change in hematological indicators is an independent predictor for invasion and can be incorporated into the treatment decision-making process for DCIS. Invasion tumor cells exhibit a stronger proliferative capacity compared with the in-situ ones. There are linear relationships in HER2 expression and histological grades between DCIS and matched IDC. DCIS subclones with different histological grades will develop into invasive carcinomas separately.
Experimental Study of Vane Heat Transfer and Aerodynamics at Elevated Levels of Turbulence

A four vane subsonic cascade was used to investigate how free stream turbulence influences pressure surface heat transfer. A simulated combustor turbulence generator was built to generate high level (13 percent) large scale (Lu approximately 44 percent inlet span) turbulence. The mock combustor was also moved upstream to generate a moderate level (8.3 percent) of turbulence for comparison to smaller scale grid generated turbulence (7.8 percent). The high level combustor turbulence caused an average pressure surface heat transfer augmentation of 56 percent above the low turbulence baseline. The smaller scale grid turbulence produced the next greatest effect on heat transfer and demonstrated the importance of scale on heat transfer augmentation. In general, the heat transfer scaling parameter U(sub infinity) TU(sub infinity) LU(sub infinity)(exp -1/3) was found to hold for the turbulence. Heat transfer augmentation was also found to scale approximately on Re(sub ex)(exp 1/3) at constant turbulence conditions. Some evidence of turbulence intensification in terms of elevated dissipation rates was found along the pressure surface outside the boundary layer. However, based on the level of dissipation and the resulting heat transfer augmentation, the amplification of turbulence has only a moderate effect on pressure surface heat transfer. The flow field turbulence does drive turbulent production within the boundary layer which in turn causes the high levels of heat transfer augmentation. Unlike heat transfer, the flow field straining was found to have a significant effect on turbulence isotropy. On examination of the one dimensional spectra for u' and v', the effect to isotropy was largely limited to lower wavenumber spectra. The higher wavenumber spectra showed little or no change. The high level large scale turbulence was found to have a strong influence on wake development. The free stream turbulence significantly enhanced mixing resulting in broader and shallower wakes than the baseline case. High levels of flow field turbulence were found to correlate with a significant increase in total pressure loss in the core of the flow. Documenting the wake growth and characteristics provides boundary conditions for the downstream rotor.
Effect of different pruning operations on the plant growth, phytohormones and transcriptome profiles of the following spring tea shoots

Pruning as an important agronomic operation plays a crucial role in the regulation of tea plant growth, development and dry tea quality. The effects of different pruning operations on the plant growth, phytohormones and transcriptome profiles of the following spring tea shoots were studied. Pruning-treated samples had generally increased median of the weight of 100 buds (two leaves and one bud, 15.5−20.5 g) and longer stem diameter (1.7−1.8 mm) whereas shorter shoot length (34.6−59.2 mm) at the stage of two leaves and one bud, compared with unpruned samples (14.0 g, 1.7 mm, 87.4 mm), among which heavy pruning in mid April and early May greatly accelerated the development of the following spring tea shoots. The levels of phytohormones (auxin, gibberellin 1, gibberellin 3, and trans -zeatin) were significantly increased in the spring buds of tea plants heavily pruned in May. The KEGG result indicated that the pathways of plant–pathogen interaction, plant hormone signal transduction and circadian rhythm were regulated by different pruning treatments. Heavy pruning in April or May, without autumn pruning was suitable for producing premium green tea due to the early development and the higher weight of 100 buds. This study provides scientific guidance to regulate the growth of the following spring tea shoots using plant pruning
Awake Sternal Fixation Using the Ultrasound-Guided Superficial Parasternal Intercostal Plane Block in a Patient With Cervical Spine Fracture

We present the use of a bi-level, bilateral ultrasound-guided (US-guided) superficial parasternal intercostal plane block (S-PIP) for main anesthetic method in a 71-year-old patient with a C2 vertebral fracture undergoing repair of a sternal fracture. Conscious sedation was provided using midazolam and a remifentanil infusion. The patient had an uneventful recovery and was discharged from the hospital on the first postoperative day without complications. An US-guided S-PIP should be considered when patients are deemed at high risk for general anesthesia, especially in trauma patients with a cervical spine fracture.
Effects of Supplemental Light Spectra on the Composition, Production and Antimicrobial Activity of Ocimum basilicum L. Essential Oil

This study was performed to investigate the effects of different supplemental light spectra and doses (duration and illuminance) on the essential oil of basil (Ocimum basilicum L.) cultivated in the net-house in Vietnam during four months. Ten samples of basil aerial parts were hydrodistilled to obtain essential oils which had the average yields from 0.88 to 1.30% (v/w, dry). The oils analyzed using GC-FID and GC-MS showed that the main component was methyl chavicol (87.4–90.6%) with the highest values found in the oils of basil under lighting conditions of 6 h/day and 150–200 µmol·m−2·s−1. Additional lighting conditions caused the significant differences (p < 0.001) in basil biomass and oil production with the highest values found in the oils of basil under two conditions of (1) 71% Red: 20% Blue: 9.0% UVA in at 120 μmol·m−2·s−1 in 6 h/day and (2) 43.5% Red: 43.5% Blue: 8.0% Green: 5.0% Far-Red at 100 μmol·m−2·s−1 in 6 h/day. The oils of basil in some formulas showed weak inhibitory effects on only the Bacillus subtilis strain. Different light spectra affect the biomass and essential oil production of basil, as well as the concentrations of the major components in the oil.
Simulation of Fluid Flow during Egg Pickling under Different Inlet and Outlet Conditions in a Pulsed Pressure Tank with Liquid Circulation

Pulsed pressure pickling is an emerging highly efficient osmotic dehydration technique. However, the immobility of the pickling liquid and the material, the formation of layers, and the uneven pickling efficiency in different sections make it difficult to use industrially. This work aims at improving and optimizing the conditions of fluid flow in the pickling tank with a liquid-cycle system to reduce the unevenness in the production process. Fluid flow around the eggs was numerically investigated by solving three-dimensional Reynolds-averaged Navier–Stokes equations within the flow regime, adopting different angles and positions at the inlet and outlet. The simulation results show that the inlet with a radial deflection of 35° and the outlet with axial direction were characterized by the best flow efficiency. Under these conditions, the average flow velocity and the global uniformity index were 0.153 m/s and 0.407, respectively. Furthermore, the experiments were carried out using an equivalent scale model of the pulsed pressure equipment with liquid circulation. The experimental results showed that, under optimal conditions, the salt content in all four layers of the egg white was about 2.8% after 48 h. This study provides a solution to ensure the constant salinity of different layers of pickled eggs and to improve pickling efficiency, especially in industrial-scale production.
The Influence of Diabetic Peripheral Neuropathy on the Duration of Sciatic Nerve Block with 1.3% Liposomal Bupivacaine and 0.25% Bupivacaine Hydrochloride in a Mouse Model

Little is known regarding the pharmacological properties of extended-release local anesthetics in the setting of diabetic peripheral neuropathy. We investigated and compared the duration of sciatic nerve block following administration of clinically relevant concentrations of liposomal bupivacaine (LB) and bupivacaine hydrochloride (BH) in diabetic mice with peripheral neuropathy. In this prospective, randomized, and double-blind study, twenty-four female C57BL/6J-OlaHsd mice were assigned to a streptozotocin-induced type 1 diabetes group and a control group without diabetes. The presence of peripheral neuropathy was established by assessing the duration of thermal latency of the plantar and tail-flick tests, following which both groups were subdivided into two subgroups in which 35 mg/kg of 1.31% LB and 7 mg/kg of 0.25% BH were respectively administered for sciatic nerve block. The average sensory block duration with BH was 106 min and 117.1 min in the control and diabetic groups, respectively. With LB, the average sensory block duration was 118 min in the control mice, while in mice with diabetic peripheral neuropathy, the average block duration was significantly longer and above the 270 min limit set in our study. Accordingly, sensory block duration was longer with LB compared to BH, and diabetic peripheral neuropathy significantly increased sciatic nerve block duration with LB.
Empowerment of Abandoned Ponds for Sustainable Mangrove Rehabilitation Activities in Percut Sei Tuan, Deli Serdang, Indonesia

Mangrove ecosystems provide important functions for ecosystem service. However, the degradation of mangrove forests, especially conversion to aquaculture ponds is a driver for deforestation. Therefore, this study aimed to analyze the mangrove vegetation and duration of inundation in ponds before and after rehabilitation activities were conducted on abandoned ponds. In this analysis, we used the census method to collect structural data, the Important Value Index (IVI), composition and structure, and the diversity index. To determine the duration of inundation at the observation sites in a pond in Tanjung Rejo, Percut Sei Tuan village, we deployed one water logger and two Mini Buoys at ponds. At the observation site, eight pure mangrove species have been founded, namely Avicennia alba, A. marina, Bruguiera gymnorrhiza, Excoecaria agallocha, Rhizophora apiculata, R. mucronata, R. stylosa, and Nypa fruticans. The main species was A. marina which is a total of 756 idv/ha at the seedling stage 52.81 idv/ha at the sapling stage, and 268.09 idv/ha at the tree level. The highest IVI has founded in seedlings, saplings, and trees at A. marina, which was 99.30%. 80.41% and 94.49%, respectively. Rehabilitated Avicennia spp that grew only 2.4% from 2000 seedlings. The low growth of seedlings was influenced by the pond condition which was always in a state of flooding. The current study provides important information that in carrying out planting or rehabilitation activities it is necessary to determine which inundation rotation should be a priority considered.
IAU Symposium 241 - Stellar Populations as Building Blocks of Galaxies

Stellar populations, building blocks of galaxies, are direct tracers of the star formation history, the chemical enrichment and the assembly of galaxies in the Universe. They therfore allow us to understand how galaxies formed and evolved. This last decade has witnessed a revolution in our observations of galaxies; with larger telescopes and new instruments we are not only able to look deeper in the Universe, we can also study nearby galaxies with greater detail. The fact that now is becoming possible to resolve stars up to the distance of Virgo Cluster allows us to rigorously compare and calibrate the analysis of the integrated light with resolved stellar populations. These Proceedings report the considerable progress made in recent years in this topic. Theorists and observers, researchers of resolved and unresolved stellar populations, discussed the ingredients of stellar population models, and rigorously compared them to new data, forcing theorists to develop more refined models and methods to derive the physical parameters of the stellar populations. New results from the Milky Way, the Local Group, and nearby and distant galaxies were presented.
Investigation of nonlinear dielectric properties in Sr0.75Ba0.25Nb2O6 relaxor ferroelectric thin films

The ac and dc driving fields dependence of the dielectric permittivity for the strontium barium niobate relaxor ferroelectric thin films has been investigated. The nonlinear dielectric properties were obtained by using the measurements of the dielectric permittivity of the material as a function of the ac and dc “bias” electric field amplitude in wide frequency 100 Hz‐10 MHz and temperature 50‐450 K intervals. The results hint the existence of a true mesoscopic dielectric relaxor response in the ferroelectric thin film, which is very similar to those observed in bulk relaxor ferroelectrics. An anomalous behavior of the NL dielectric response was observed when submitted to moderate dc electric fields levels, indicating a crossover from paraelectric to a glasslike behavior on cooling the sample toward the freezing transition. The obtained results were analyzed within the framework of the models proposed in the current literature. © 2008 American Institute of Physics. DOI: 10.1063/1.2828143
The correlation of clinical status and imaging findings in patients with chronic low back pain

Background/Aim: Chronic low back pain (LBP) is a common health problem that negatively affects quality of life. A multidisciplinary approach is recommended in treating chronic LBP. In the literature, we could not find any study examining the relationship between clinical status, activities of daily living, angular measurements in the lumbar region, and spondylosis level in patients with LBP. We aimed to reveal whether there is a relationship between the severity of the clinical condition and these angular measurements. In addition, there are opposing views in the literature about the relationship between obesity and LBP, and we planned to investigate this issue in our study. We aimed to investigate the correlation between clinical, functional evaluations, and radiographic findings in patients with chronic LBP and examine the relationship between these variables and gender and educational level. We also determine the effects of age, body mass index (BMI), and waist circumference on these variables. Methods: The research was designed as a cross-sectional, uncontrolled study. Seventy patients aged 18–65 years with chronic LBP and VAS (Visual Analog Scale) values ≥ 3 were included. Patients were grouped by gender and educational level. Lumbar lordosis angle (LLA), sacral inclination angle (SIA), and Kellgren-Lawrence (K-L) grade were recorded. VAS, Oswestry Disability Index (ODI), Back Pain Functional Scale (BPFS), and Katz Activities of Daily Living (Katz-ADL) scores were calculated. Pearson correlation analysis determined the normal distribution status of the variables. Spearman’s correlation analysis evaluated the linear relationship between ODI and BPFS and LLA and SIA continuous variables. A p-value of < 0.05 was considered statistically significant. Results: A total of 70 patients (47 females and 23 males) with chronic LBP were included in the study. Mean BMI (28.2 [6.1] kg/m2) and waist circumference (95.7 [12.7] cm) of the patients were above normal ranges (normal BMI: 18.5–24.99 kg/m², normal waist circumference: < 80 cm for women, < 90 cm for men). Katz-ADL (P = 0.006) and BPFS scores (P = 0.027) were lower, and LLA (P = 0.042) was higher in women than men. The BPFS score was lower in the low-level education group than in the high-level education group (P = 0.004). There was a positive correlation between age and SIA (P = 0.028, r = 0.262), and between age and K-L grade (P < 0.001, r = 0.633). A positive correlation was also observed between BMI and K-L grade (P = 0.001, r = 0.395) and waist circumference and K-L grade (P < 0.001, r = 0.442). Conclusion: No correlation was found between functional clinical scales and radiographic findings in patients with chronic LBP. Increasing age, BMI, and waist circumference were associated with more severe radiographic osteoarthritis of the lumbar spine, whereas female gender and low educational level were related to lower functional levels. Further extensive studies, including a larger number of patients, are needed to clarify our results.