Miracle-dz/UniFAR-FTUs huggingface dataset:
Phytotoxic potential of aqueous leaf extract of Tocoyena formosa and Rudgea viburnoides

Submitted on october 23 , 2018 and accepted on August 26th, 2019. 1 This paper is part of the first author’s master dissertation. 2 Universidade Federal de Mato Grosso, Programa de Pós-Graduação em Agricultura Tropical, Cuiabá, Mato Grosso, Brazil. harhilares@gmail.com ; coelhomfstrela@gmail.com ; leohmurga@gmail.com; carlaspiller@gmail.com EARTH University, Guácimo, Limón, Costa Rica. bert.cowo@gmail.com *Corresponding author: sharhilares@gmail.com Phytotoxic potential of aqueous leaf extract of Tocoyena formosa and Rudgea viburnoides
Impacts of flooding, nitrogen-fertilization, and soil-depth on sugarcane nutrients grown on Histosols

Abstract Sustainable production in the Everglades Agricultural Area (EAA) is confounded by decreasing soil depth and high annual rainfall. Formerly a sawgrass marsh, Histosols predominate much of the EAA and these soils have frequently flooded following their drainage in the early 20th century. Subsidence has increased inundation frequency as soil depth has decreased to less than 25 cm in many locations. A 2-year lysimeter study was conducted to examine alternative management practices for improved agricultural sustainability given frequent flooding and reduced oxidation rates on Histosols. Specific management factors examined included water-table, soil depth, and nitrogen (N) fertilizer effects on sugarcane leaf nutrient concentrations and soil nutrient cycling. The trial utilized soil depths of 13 and 25 cm, water tables of constant and periodically flooded, and N fertilizer rates of 0 and 168 kg ha−1 year−1. Periodic flooding increased plant uptake of manganese (Mn), silicon (Si), and boron (B). Yield increases associated with additional N indicate a potential need to develop fertilizer rate recommendations for shallow Histosols. Soil depth impacted sugarcane nutrient uptake with 25 cm of soil depth significantly affecting examined leaf nutrient concentrations except iron (Fe). Sugarcane yield may benefit if additional N and potassium (K) are added at rates specific to soil depth. Proximity to bedrock led to excessive calcium (Ca) uptake and low K and Fe DRIS (Diagnosis and Recommendation Integrated System) values were below recommendations. Data from this study can assist development of precision agricultural practices in the EAA that utilize soil depth.
Gene Regulation and Chromatin Structure of Mammalian Olfactory Receptors

Mammals sense odors by expressing the gene family of olfactory receptors (ORs). Despite the massive family size — around 1,000 OR genes in the mouse genome and 400 in human, each sensory neuron randomly expresses one, and only one, OR. This phenomenon, termed the “oneneuron-one-receptor” rule, underlies both odor sensing in the nose and the formation of an odor map in the brain. However, it remains a mystery how this rule is established. Combining theoretical modeling, single-cell transcriptomics, spatial transcriptomics, and single-cell 3D genome structures, we investigated the regulation of OR genes during neuronal development. We identified a fundamental kinetic constraint in a recent model of epigenetic OR regulation, uncovered a surprising phenomenon of transient multi-OR expression in immature neurons, created by far the most comprehensive spatial map of mouse ORs in the nose, and revealed for the first time 3D genome structures of single diploid human and mouse cells including olfactory sensory neurons. Our interdisciplinary approach provided valuable insights into the molecular mechanism behind the “one-neuron-one-receptor” rule of OR expression; and our methods could be widely applicable to other systems where gene regulation and chromatin structure underlie important physiological functions.
Effect of Sources and Levels of Zinc on Growth and Yield of Wheat (Triticum aestivum L.) in Loamy Sand

Wheat [Triticum aestivum (L.)] has been described as “King of cereals” and one of the most important staple food crop cultivated in 43 countries of the world. Wheat has its own outstanding importance as a human food; the nutritive value of wheat is fairly high as compared to other cereals. It contains 11.80, 1.50, 71.20, 1.50, 0.50, 0.32, percent protein, fat, carbohydrate, mineral matter, calcium and phosphorus, respectively (Swaminathan et al., 1981). Wheat (Triticum aestivum L. emend. Fiori & Paol.) is the number one cereal of the world and being grown on the largest area. In India, wheat is the second most important food crop next to rice and it contributes nearly 35 per cent to the national food basket. Its International Journal of Current Microbiology and Applied Sciences ISSN: 2319-7706 Volume 8 Number 10 (2019) Journal homepage: http://www.ijcmas. com
Quality preservation and safety ensurement of a vegetable smoothie by high‐pressure processing

This research aims to evaluate the effect of a previously optimized high‐pressure processing (HPP) treatment on the vegetable smoothie stability during 28 days at 5 °C and on the inactivation of a contamination with Listeria monocytogenes and Escherichia coli O157:H7 surrogates during 12 days at 15 °C. HPP (630 MPa/6 min) reduced native microbiota to values below detection limit (DL = 1 log CFU/g) and significantly reduced polyphenol oxidase, peroxidase, and pectin methylesterase initial activities (16.7%, 29.6%, and 70.7%, respectively), maintaining significant lower values than control during storage. In addition, smoothie's soluble solids and pH were neither modified with treatment nor storage time, while greater retention of color and nutritional indicators was noted on treated samples during storage. Moreover, HPP allowed controlling 6 log CFU/g surrogate counts, maintaining them below DL during storage. Hence, optimized HPP treatment is effective to improve the quality stability of the product besides ensuring their safety when contamination occurs. PRACTICAL APPLICATIONS: High‐pressure processing is an alternative preservation method that not only is effective for microbial and enzymatic control but also has demonstrated promising results in antioxidant and bioactive compounds preservation, which is of especial relevance in foods such as fruit and vegetable smoothies that contain large amount of them. Recently, smoothies have gained strength in the market as part of the trend toward healthy eating habits. However, there is little information available on the effect of conservation technologies on this type of matrix. This is one of the first studies addressing the effect of high hydrostatic pressure processing during the storage of mixed fruit and vegetable smoothies, providing information of great interest for an industry in full growth.
Current concepts in assessing quality of life in elderly patients with hip hemiarthroplasty: a systematic literature review

Background:This is an updated systematic review of the quality of life (QOL) scales being used in hemiarthroplasty research. The principal aim is to determine optimal choices for use in daily clinical practice. Methods:The scales reviewed in terms of reliability, responsiveness, validity, and practicality were: Short Form-36, Short Form-12, Nottingham Health Profile, EuroQol, Musculoskeletal Function Assessment, Short Musculoskeletal Function Assessment, Barthel Index, Harris Hip Score, Oxford Hip Score, Modified Hip Rating Questionnaire, Charnley Hip Score, Matta Functional Hip Score, and Western Ontario and McMaster Universities Arthritis Index. Results:EuroQol has demonstrated some degree of ability to discriminate between patients with closed reduction or hemiarthroplasty. The Harris Hip Score performed well on response rate, discriminatory ability, and responsiveness. The Barthel Index had ceiling effects. The Short Musculoskeletal Function Assessment has been recommended as one of the tools to use in evaluating outcome after a hip fracture but is challenging to administer. Conclusions:Based on our analysis we recommend the EuroQol and Harris Hip Score. Further research is necessary to evaluate the validity, reliability, responsiveness, and practicality of the current tools being used in hemiarthroplasty trials.
Progesterone-releasing vaginal ring for luteal phase support after superovulation and intrauterine insemination cycles, a pilot study

Objective: The main objective of this pilot study was to determine whether a progesterone-releasing vaginal ring is a good alternative for luteal phase support for patients undergoing intrauterine insemination after ovulation induction with sc gonadotrophins. material and methods: We performed a multi-center study involving three different reproductive medicine units. Patients included were diagnosed with unexplained infertility rFSH (Puregon ®) and ovulation induction with urinary HCG (Pregnyl ®). The day of insemination patients were randomized to receive luteal phase supplementation with progesterone vaginal ring (Fertiring ®) or no supplementation. Results: One hundred patients were invited to participate, and completed the study. Forty seven received luteal phase support with Fertiring ®. Overall the pregnancy rate was 15%. It was higher, although without reaching statistical Fertirng ® (19.1%) than in the group without supplementation(11.3%). Conclusions: In this study, patients undergoing ovulation induction with Puregon ® and received luteal phase support with Fertiring ® showed a higher pregnancy rate than those who received no luteal phase support, although statistical RESUmEN Objetivo: El objetivo principal de este estudio piloto fue comparar la frecuencia de embarazo por ciclo en pacientes sometidas a inseminacion intrauterina despues de la induccion de ovulacion con o sin apoyo de la fase lutea con Fertiring ®. materiales y metodo: Se realizo un estudio multicentrico, con la participacion de tres unidades de medicina reproductiva. Las parejas incluidas tenian el diagnostico de infertilidad sin causa aparente y era su primer ciclo de inseminacion intrauterina tras induccion de la ovulacion con FSHr (Puregon ®) e induccion de la ovulacion con HCG urinario (Pregnyl®). El dia de la inseminacion las pacientes fueron randomizadas a recibir suplemento de fase lutea con un anillo vaginal con progesterona (Fertiring®) o a ningun suplemento. Resultados: Cien pacientes fueron invitadas y completaron el estudio, 47 recibieron soporte de fase lutea con Fertiring® y 53 no recibieron. La frecuencia global de embarazo en el grupo que recibio soporte de fase lutea con Fertirng® (19,1%) que en el grupo que no recibio (11,3%). Conclusiones: En este estudio, las pacientes sometidas a induccion de la ovulacion con Puregon® y que recibieron soporte de fase lutea con Fertiring® mostraron una mayor frecuencia de embarazo que aquellas que no recibieron sopor-
Distributions of Periodontal Attachment Levels

Distributions of periodontal attachment levels at probing sites within patients have traditionally been used in clinical diagnosis and treatment planning. Progression from mild to moderate to severe disease is generally associated with increasing magnitudes of attachment loss at greater percentages of sites. Recent analyses of distributions of periodontal attachment levels have suggested three general patterns of loss defined by: (1) loss at less than about one third of all sites, (2) more widespread disease with multiple peaks and (3) normally distributed loss with virtually all sites being affected. In attempting to simulate these three patterns using a model based on the burst theory of periodontal attachment loss, divergent assumptions about burst magnitude, frequency, and possible local immunity were required. These findings were used to support the hypothesis that distinctly different disease processes are associated with the different patterns of attachment level. In the present investigation an al.
Kinetic Modeling of and Effect of Candy Additives on the Candy–Cola Soda Geyser: Experiments for Elementary School Science through Physical Chemistry

When Mentos candies are dropped into a bottle of Diet Coke, a foamy fountain jets out of the beverage container. It has previously been argued that ingredients found in Mentos candies significantly enhance this fountaining effect. Other previous work has demonstrated that the kinetics of foam production can be quantitatively monitored using a device constructed from inexpensive, easily obtained materials. In the results reported here, students used this simple device to monitor the kinetics of foam production in the Diet Coke and Mentos experiment and to draw conclusions about the system. It was possible to model the kinetic data obtained using kinetic mechanisms that involve irreversible first-order steps. Furthermore, the data collected allowed students to acquire evidence that the kinetics of foam production appears to be unaffected by the presence of certain ingredients in candies and gums, in contrast to previous claims. Many of the protocols described herein can be carried out simply and inexpensively, making them useful for high school, introductory, and general chemistry courses. In addition, the kinetic data collected are of sufficient quality to allow for analysis sophisticated enough for use in student research projects and physical chemistry courses.
The effect of a water exercise on gait characteristics in the elderly post stroke patients

Objective: To investigate the effect of long-term water exercise on gait parameters in the elderly post stroke patients. Design: One group pretest-posttest design. Methods: Twenty elderly post stroke patients (age: 56.5±10.1 years, height: 168.6±5.8 cm, body mass: 69.3±6.9 kg, handicapped level: 2.5±0.8) participated in this study. Participants took part in gait training of 1 hour per day, three days per week, for three months. Participants’ gaits were analyzed to find the effect of 3 months water exercise by a 3-D motion analysis with 8 infrared camera and 1 force plate (sampling frequency: 100 and 1,000 Hz, respectively). A paired t-test was used to find the significance with significant level as 0.05. Results: Gait velocity, step length & step width significantly increased, and asymmetric index for gait parameters significantly decreased after the water exercise (p＜0.05). Conclusions: The water exercise effectively affect on patients’ gait ability and electromyography analysis will be needed further study.
Impact of Smoking and Alcohol Consumption on Oxidative Status in Male Infertility and Sperm Quality

The most common unhealthy lifestyle factors like cigarette smoking and drinking alcohol have controversial reports on how these impact male fertility. The present study assessed the potential effects of these habits on sperm quality, male reproductive hormones, and blood plasma oxidative profile in 133 infertile men with 124 fertile, healthy controls. Among the participants, 28 (10.8 %), 29 (11.2 %), 33 (12.8 %), 34 (13.2 %) fertile men were non-alcoholics and non-smokers (total abstainers), smokers, alcohol drinkers, and smokers plus alcohol drinkers, respectively. On the other hand, 32 (12.4 %), 30 (11.6 %), 34 (13.2 %), 37 (14.3 %) infertile men were total abstainers, smokers, alcohol drinkers, and smokers plus alcohol drinkers, respectively. The conventional sperm parameters and reproductive hormone levels were found to be significantly different in the subsets of infertile men than those of fertile men (p<0.001). In these subsets of infertile men, blood plasma malondialdehyde, nitric oxide concentrations were significantly higher and superoxide dismutase, reduced glutathione activities were significantly lower when compared to fertile men and infertile men total abstainers group (p<0.001). In infertile subjects, particularly smoking-alcohol drinking group was more affected than only smoking or alcohol drinking groups. Furthermore, these oxidative markers were correlated with sperm concentration, motility, and morphology, except nitric oxide concentration, which was only associated with sperm motility. These findings highlighted that blood plasma antioxidants are as efficient as seminal plasma antioxidants in male fertility evaluation.
Seasonal Variation Effect on Multiple Sclerosis Activity in Patients Attending Multiple Sclerosis Clinic in Baghdad Teaching Hospital.

Multiple sclerosis is an immune mediated demyelinating disease of the central nervous system characterized by bouts of neurologic symptoms (or relapses) and increasing disability. The aim of this study is to elucidate the influence of seasonal variation on the nature and number of relapses in patients already diagnosed with multiple sclerosis. A cross- sectional retrospective study was carried out from January to May 2011 in Multiple Sclerosis clinic of neurological department in Baghdad Teaching hospital , including 100 relapsing- remitting multiple sclerosis patients ( 26 males and 74 females ) with 278 relapses who were registered over 5 years interval (2005-2010) ,data collected by reviewing patients records and analyzed statistically . Patients younger than 40 years significantly constitute 76%. of the sample. The largest percentages (14%) of patients were born on July. The total number of relapses was 278 distributed as 218 in females and 60 in males, the proportion of relapses in both sexes (73.7%) were higher in patients younger than 40 years. Regarding the pattern of multiple sclerosis relapses; the highest percentage (29.8%) was of sensory type. The peak of multiple sclerosis relapses was evident during January and April, with higher percentage (31.2%) in females during Spring . there was no significant differences in the proportion of relapses (29.1%, 34.7%) during Spring in both age groups and there was no relation between the type of relapse and season of occurrence. Conclusion: There is some seasonal effect on multiple sclerosis relapses, they were higher in Spring, and lower in Summer. Key Wards: multiple sclerosis, relapse, season.
Tertiary treatment of municipal wastewater using isolated algal strains: treatment efficiency and value-added products recovery

ABSTRACT Two microalgal strains (Chlorella sorokiniana, A&B,) grown optimally at pH 9 (A) and 7 (B) were isolated from a municipal wastewater treatment plant. These strains were used to check their efficacy for nutrients and organic carbon removal capacities from the tertiary wastewater. The strains were characterised using 18S rDNA sequencing method and both the strains closely related to Chlorella sorokiniana. Different inoculum doses (IDs) of both the strains were tried to check their efficacy on wastewater treatment. Due to the increase in the IDs, hydraulic retention time decreased from 6 d to 1 d. On an average, 12–100% of total kjeldahl nitrogen, 53–96% NO3–N, and 59–92% PO4–P, were removed. Despite the same growth environment, strain A with the highest ID (700 mg/L) showed the best performance in terms of overall organic carbon removal, nutrient removal, and value-added products recovery. Strain A showed an increase in carbohydrate and protein content by 42% and 13%, respectively. Both the strains showed luxury phosphorus uptake and found suitable for advanced wastewater treatment.
Activation of phospholipase Cγ by PI 3-kinase- induced PH domain-mediated membrane targeting

Signaling via growth factor receptors frequently results in the concomitant activation of phospholipase Cγ (PLCγ) and phosphatidylinositol (PI) 3-kinase. While it is well established that tyrosine phosphorylation of PLCγ is necessary for its activation, we show here that PLCγ is regulated additionally by the lipid products of PI 3-kinase. We demonstrate that the pleckstrin homology (PH) domain of PLCγbinds to phosphatidylinositol 3,4,5-trisphosphate [PdtIns(3,4,5)P3], and is targeted to the membrane in response to growth factor stimulation, while a mutated version of this PH domain that does not bind PdtIns(3,4,5)P3 is not membrane targeted. Consistent with these observations, activation of PI 3-kinase causes PLCγ PH domain-mediated membrane targeting and PLCγ activation. By contrast, either the inhibition of PI 3-kinase by overexpression of a dominant-negative mutant or the prevention of PLCγ membrane targeting by overexpression of the PLCγ PH domain prevents growth factor-induced PLCγ activation. These experiments reveal a novel mechanism for cross-talk and mutual regulation of activity between two enzymes that participate in the control of phosphoinositide metabolism.
Determining the Thickness and Completeness of the Shell of Polymer Core–Shell Nanoparticles by X-ray Photoelectron Spectroscopy, Secondary Ion Mass Spectrometry, and Transmission Scanning Electron Microscopy

Core–shell nanoparticles (CSNPs) have become indispensable in various industrial applications. However, their real internal structure usually deviates from an ideal core–shell structure. To control how the particles perform with regard to their specific applications, characterization techniques are required that can distinguish an ideal from a nonideal morphology. In this work, we investigated poly(tetrafluoroethylene)–poly(methyl methacrylate) (PTFE–PMMA) and poly(tetrafluoroethylene)–polystyrene (PTFE–PS) polymer CSNPs with a constant core diameter (45 nm) but varying shell thicknesses (4–50 nm). As confirmed by transmission scanning electron microscopy (T-SEM), the shell completely covers the core for the PTFE–PMMA nanoparticles, while the encapsulation of the core by the shell material is incomplete for the PTFE–PS nanoparticles. X-ray photoelectron spectroscopy (XPS) was applied to determine the shell thickness of the nanoparticles. The software SESSA v2.0 was used to analyze the intensities of the e.
Fluid Intake of European Children and Adolescents

Few studies have assessed total water intake in European children and adolescents, and fewer have evaluated the types of beverages being consumed in relation to childhood obesity and sedentary behaviors. Water intake and beverage consumption in the Healthy Lifestyle in Europe by Nutrition in Adolescence Cross-sectional Study, a large, pan-European study in adolescents aged 12.5 to 17.5 years, are described in terms of gender and age differences and in relation to screen-based sedentary behaviors. Dietary intake was measured in terms of fluids (milliliters) and energy (kilojoules) using two 24-hour recall assessments in 2741 adolescents. Sugar-sweetened beverages accounted for the largest amount of energy intake per person from beverages, and water, the largest amount of fluid. However, 12.1% of adolescents did not drink plain water at any time, with 69.4% of boys and 64.4% of girls having a total water intake below the levels currently recommended by the European Food Safety Authority. A causal link between sweetened beverage consumption and childhood obesity has not been definitively shown; however, the consumption of sugar-sweetened beverages during sedentary activities could contribute to the promotion of childhood obesity. In general, adolescents spending more than 4 h/d on sedentary behaviors were more likely to consume sweetened beverages than those spending fewer than 2 hours on the same activities. Efforts should be made to promote healthy foods and beverages in children and adolescents and to replace sedentary behaviors with physical activity.