Miracle-dz/UniFAR-FTUs huggingface dataset:
Assessment of Nutritional Patterns of Pregnant Adolescents in Aswan City

Adolescent pregnancy is a worldwide health problem. It has been considered as a major health problem to pregnant women and their newly born babies especially in developing countries to the extent that it received considerable attention. Objective: To assess nutritional patterns of pregnant adolescents in Aswan City. Settings: Ten Maternal and Child Health (M.C.H) centers in Aswan city were randomly chosen from the available 36 M.C. H centers, affiliated to the Ministry of Health. Subjects: A convenience sample of 300 pregnant adolescents aged 15-21 years was selected from the previous settings, (30 from each MCH center). Tool: Adolescent pregnant women nutritional patterns structured interview schedule was developed by the researcher. It entailed the following parts: Part one: Sociodemographic and reproductive history. Part two: Nutritional patterns structured interview schedule that comprised: a. Knowledge about nutrition and elements of balanced diet. b. Factors affecting study subject's choice of food. c. Knowledge about risks of malnutrition. d. Nutritional behaviors or habits of pregnant adolescents. Results: A poor total score regarding knowledge about nutrition and elements of balanced diet was obtained by 58.0 % of the study subjects. Regarding factors that affect choice of food, nearly two thirds (63.3%) of the study subjects’ husbands were responsible for buying food. Choosing food was the responsibility of wives among 57.3% of the study subjects More than twothirds of the study subjects always had fresh fruits, vegetables and dairy products at home both. Regarding knowledge about risks of malnutrition. Less than twothirds (65.0%) and slightly more than one third (34.0%) of the study subjects gained poor and fair total score grade (respectively). On the other hand, the vast majority (94.3%) of the study subjects gained good total score of nutritional habits. Conclusion: It was concluded that the majority of the study subjects gained good nutritional habits in spite of their poor knowledge. Many adolescents have poor diet quality and lack knowledge about the appropriate nutrition. As a result, engaging in unhealthy dietary practices. Recommendations: Improving the nutritional status of adolescent girls before and during pregnancy is recommended through providing necessary knowledge about the good eating habits and nutritional requirements. Enforce mass media should provide nutritional education programs to adolescents about importance of nutrition and risks of malnutrition especially for pregnant adolescents.
Functional crosstalk between the carrier translocase machinery and YME1 complex maintains mitochondrial proteostasis and integrity

The TIM22 pathway cargos are essential for sustaining mitochondrial proteostasis as an excess of these proteins leads to proteostatic stress and cell death. Yme1 is an inner membrane metalloprotease that regulates proteostasis with its chaperone-like and proteolytic activities. Although the mitochondrial translocase and protease machinery are critical for organelle health, the functional link between these complexes remains unexplored. The present study unravels a novel genetic connection between the TIM22 complex and YME1 machinery in maintaining mitochondrial proteostasis and quality control. Our genetic analyses indicate that impairment in the TIM22 complex rescues the respiratory growth defects of cells without Yme1. We further demonstrate that Yme1 is essential for the stability of the TIM22 complex and regulating the proteostasis of the TIM22 pathway substrates. Moreover, impairment in the TIM22 complex suppressed the mitochondrial structural and functional defects of Yme1 devoid cells. Notably, the functional dependence between the TIM22 and YME1 complexes remains functionally conserved from yeast to humans. Our findings suggest that excessive levels of the TIM22 pathway substrates could be one of the reasons for the respiratory growth defects of cells lacking Yme1 and compromising the TIM22 complex compensate for the imbalance in mitochondrial proteostasis caused by loss of Yme1.
Immediate implant placement with immediate provisionalization into extraction sockets with labial plate dehiscence defects within the maxillary esthetic zone. A clinical case series study

Aim: The aim of this study was to demonstrate the effect of immediate implant placement with immediate loading combined with GBR using a mix of autogenous bone and xenograft with a collagen membrane in type 2 extraction sockets on amount and level of labial Plate of bone reconstruction, primary stability and pink esthetic score (PES) after 6 months post-operative Methodology: A total of 15 patients with type 2 extraction sockets, underwent a traumatic extraction of their teeth in maxillary esthetic zone from right second premolar to left second premolar, and received immediate implant placement with guided bone regeneration that achieved by harvesting autogenous bone from chin and mixed with xenograft and placement of a collagen membrane inside the socket without flap elevation, the graft and membrane were fixed by a provisional restoration that screw-retained on the implant. Outcome measures were: amount of graft remodeling primary stability and PES 6 months post-operative. Results: Mean bone level immediately post-operative was 3.33+0.68 that decreased to 2.87+0.62mm 6 months later the difference was statistically significant (p<0.001), mean PES immediately postoperative was 9.85+1.07 that increased to 12.85+0.80 six months postoperative the difference was statistically significant (p<0.001), mean stability immediately postoperative was 65.6+3.2 that increased to 73.7+2.4 six months postoperative the difference was statistically significant (p<0.001) Conclusion: Guided bone regeneration with immediate implantation and loading in type 2 sockets has a significant influence on labial plate reconstruction, PES enhancement and primary stability elevation. (226) Merna Yehia Ghoneim, et al. E.D. J. Vol. 68, No. 1
Incentive Pay Prior to CEO Turnover When Effort Choices Have Lasting Effects

We present a modified principal-agent model to identify a link between the anticipated likelihood of future CEO turnover and the optimal sensitivity of incentive pay to firm performance. The analysis focuses on the optimal sequence of standard one-period incentive contracts when CEO effort choices have lasting effects on firm performance. In such a model, an increase in the anticipated likelihood of turnover reduces the impact of future incentive contracts on current CEO effort, and induces a compensatory increase in the optimal sensitivity of current CEO compensation to current firm performance. We find empirical evidence in support of this prediction for a sample of over 3,000 US firms. Using an executive-specific fixed effects model, we find that among CEOs who depart within two years, the sensitivity of current incentive pay to changes in current firm performance is greater when there is a higher anticipated likelihood of CEO turnover as proxied by departures that reflect a planned succession and departures by CEOs who have reached retirement age. As expected, this increase in the sensitivity of current incentive pay to changes in firm performance is not found if the subsequent turnover is classified as unplanned, and thus not anticipated by the firm. JEL Classification: G30, J33, J63, M12, M52
The Efficacy of Integrating Spirituality into Prenatal Care on Pregnant Women's Sleep: A Randomized Controlled Trial

Objective The study is aimed at determining the efficacy of spiritual content counselling on improving the sleep quality and insomnia severity of pregnant women. Methods This randomized controlled trial was carried out on 40 pregnant women recruited at five health centres of Abhar, Iran, 2020. The eligible women were allocated into two intervention and control groups according to the randomized blocking method. Group counselling with spiritual content was carried out in eight sessions at 16 to 20 weeks of gestation. The control group only received routine care. Data were collected using the Pittsburgh Sleep Quality Index (PSQI) and the Insomnia Severity Index (ISI) questionnaires in three stages, before the intervention, at 28, and 36 weeks of gestation. Statistical analysis was performed using repeated measure ANOVA test, chi-square, and independent t-tests. P < 0.05 was considered significant statistical level. Results In the counselling group, the mean (SD) of a total score of sleep quality before the intervention was 9.45 (2.30) which decreased to 5.40 (1.56) in 36 weeks of gestational age, while in the control group was increased from 9.26 (2.15) to 11.47 (1.54). After the intervention based on the repeated measure ANOVA test, the mean total score of the insomnia severity, sleep quality, and its components decreased statistically in the second and third trimesters compared to the first trimester in the intervention group compared to the control group (P = 0.001). Conclusion The results showed that counselling with spiritual content could effectively ameliorate sleep quality and reduce insomnia severity in pregnant women. It seems that the approach is an acceptable basis to design intervention programs in this field that can be considered by midwives. Clinical Trial Registry and Registration Number. The study was registered at the Iranian Registry of Clinical Trials under the IRCT20150731023423N15.
Reliable and efficient parameter estimation using approximate continuum limit descriptions of stochastic models

Stochastic individual-based mathematical models are attractive for modelling biological phenomena because they naturally capture the stochasticity and variability that is often evident in biological data. Such models also allow us to track the motion of individuals within the population of interest. Unfortunately, capturing this microscopic detail means that simulation and parameter inference can become computationally expensive. One approach for overcoming this computational limitation is to coarse-grain the stochastic model to provide an approximate continuum model that can be solved using far less computational effort. However, coarse-grained continuum models can be biased or inaccurate, particularly for certain parameter regimes. In this work, we combine stochastic and continuum mathematical models in the context of lattice-based models of two-dimensional cell biology experiments by demonstrating how to simulate two commonly used experiments: cell proliferation assays and barrier assays. Our approach involves building a simple statistical model of the discrepancy between the expensive stochastic model and the associated computationally inexpensive coarse-grained continuum model. We form this statistical model based on a limited number of expensive stochastic model evaluations at design points sampled from a user-chosen distribution, corresponding to a computer experiment design problem. With straightforward design point selection schemes, we show that using the statistical model of the discrepancy in tandem with the computationally inexpensive continuum model allows us to carry out prediction and inference while correcting for biases and inaccuracies due to the continuum approximation. We demonstrate this approach by simulating a proliferation assay, where the continuum limit model is the well-known logistic ordinary differential equation, as well as a barrier assay where the continuum limit model is closely related to the well-known Fisher-KPP partial differential equation. We construct an approximate likelihood function for parameter inference, both with and without discrepancy correction terms. Using maximum likelihood estimation, we provide point estimates of the unknown parameters, and use the profile likelihood to characterise the uncertainty in these estimates and form approximate confidence intervals. For the range of inference problems considered, working with the continuum limit model alone leads to biased parameter estimation and confidence intervals with poor coverage. In contrast, incorporating correction terms arising from the statistical model of the model discrepancy allows us to recover the parameters accurately with minimal computational overhead. The main tradeoff is that the associated confidence intervals are typically broader, reflecting the additional uncertainty introduced by the approximation process. All algorithms required to replicate the results in this work are written in the open source Julia language and are available at GitHub.
BRITISH EDITORIALS PORTRAYAL OF TURKEY DURING THE 2000S: AN ANALYSIS OF THE GUARDIAN, THE FINANCIAL TIMES, AND THE DAILY TELEGRAPH 2000’LERDE TÜRKİYE’NİN İNGİLİZ BAŞYAZILARINDA TASVİR EDİLME BİÇİMLERİ: THE GUARDIAN, THE FINANCIAL TIMES VE THE DAILY TELEGRAPH İNCELEMESİ

A leading article or editorial is an opinion piece written by the editorial staff of a newspaper and represents the opinion of the publisher. This study examines the portrayal of Turkey as presented within the broad context of political media discourse in the leading articles of three influential British quality newspapers: the Guardian, the Financial Times, and the Daily Telegraph, between 2005 and 2010. The aim is to find out what arguments/issues the editorials cover in favour of or against Turkey, and whether Turkey’s multi-dimensional EastWest transformation has influenced the political discourses and the nature of news in the British press. A qualitative content analysis was performed on three newspapers’ leading articles. Findings indicate that although editorial staff of British conservative, labour, and liberal press had a great deal to talk about apparently different subjects that constitute comments on Turkey’s turbulent relationship with the European Union, or its human rights record, unending debate on secularism versus Islamist politics or lack of ethnic minority rights domestically; at the same time, they had created a rather positive, constructive and consistent political image of Turkey, by portraying the country as a rather democratic, secular, Muslim state that can create a bridge between the West and the Middle East in international affairs.
Job Satisfaction as the Mediator Between a Learning Organization and Organizational Commitment Among Lecturers

The higher educational institution needs a group of dedicated and committed lecturers to endure the institution during these turbulent times. As the organizational commitment reflects the self-identification of an employee with the organization, it has far-reaching implications on multifarious aspects in the organization. This present study investigated whether job satisfaction could mediate the relationship between learning organization and organizational commitment. A total of 452 lecturers from Heilongjiang province in China participated in this study. Structural equation modelling showed that job satisfaction significantly mediated the relationship between the dimensions of learning organization and organization, specifically on the effect of continuous learning, connection, and strategic leadership. Job satisfaction is also found to be a stronger predictor of organizational commitment than learning organization. These findings are discussed thoroughly and recommended a holistic plan to be devised that could strengthen learning organization and job satisfaction of lecturers in various aspects of the organization.
Analysis of Length of Hospital Stay of Road Crash Patients in the Philippine General Hospital’s Integrated Surgical Information System from 2008–2017

Introduction. Mobility in the Philippines has increasingly become a major issue especially with the growing economy of the country. Collisions on the road cannot be entirely avoided; thus, we focus our efforts to reducing road crashes that result in death and serious injuries. To do this, we analyzed road crash patients brought to the Philippine General Hospital (PGH). Objective. The study aimed to quantify how crash factors affect length of hospital stay (LOS) of patients brought to PGH, as well as to look for associations between the LOS and demographic and clinical variables. Methods. This is a retrospective study using database of patients admitted in PGH from 2008 to 2017. The study focused on LOS, which was used as the dependent variable for Poisson regression and Kruskal-Wallis H tests. The determinants considered in the study are socio-demographic variables such as age, sex, civil status, victim type, vehicle type, patient classification, and region of incidence, as well as clinical variables such as consult type, outcome of the patient, body parts injured, Glasgow coma score (GCS), among others. Results. We analyzed data of 4979 road crash patients from the PGH database. We found that civil status, age, patient classification, vehicle type, and province were associated with LOS. For the clinical variables, consult type, primary service, outcome of patient, body injuries, GCS and systolic blood pressure were found significant. Poisson regression suggests longer hospital stay for patients with injuries sustained in the head and neck (RR = 1.102, p < 0.001), face (RR = 1.218, p < 0.001), and extremity (RR = 1.673, p < 0.001). Conclusion. Results show that injury sustained in certain parts of the body such as head and neck, face, and extremity significantly affect LOS. Results also show that subgroups within demographic variables affect LOS. There is a need to address the ever-increasing number of road crash patients and implications to length of hospitalization.
The Effect of ForeArc Deformation on Shallow Earthquake Rupture Behavior in the Cascadia Subduction Zone

Many paleo-seismic studies find that the Cascadia subduction zone (CSZ) has the potential to produce great earthquakes (Goldfinger et al., 2012, 2017; Kelsey et al., 2002), and large tsunamis (Atwater et al., 2005; Satake et al., 2003). Based on historic tsunami records, the last great earthquake on the CSZ occurred in 1700 AD (Yamaguchi et al., 1997), was approximately a magnitude 9, and generated a trans-oceanic tsunami (Satake et al., 2003). Models of this earthquake suggest that there were along-strike differences in the slip distribution on the megathrust (Leonard et al., 2010; Wang et al., 2013), some of which correlate well with variations in megathrust geometry (e.g., subducting seamounts) (Wang et al., 2013).
DrTM+B: Replication-driven Live Reconfiguration for Fast and General Distributed Transaction Processing

Recent in-memory database systems leverage advanced hardware features like RDMA to provide transaction processing at millions of transactions per second. Distributed transaction processing systems can scale to even higher rates, especially for partitionable workloads. Unfortunately, it is challenging to sustain such high rates during live reconfiguration of partitions. In this paper, we observe that state-of-the-art approaches would cause notable performance disruption under fast transaction processing. To this end, this paper presents DrTM+B, a live reconfiguration approach that seamlessly repartitions data with little performance disruption to running transactions. DrTM+B uses a pre-copy-based mechanism to avoid excessive data transfer by leveraging common properties in recent transactional systems. DrTM+Bs reconfiguration plans reduce data movement by preferring existing data replicas, while copying data from multiple replicas asynchronously and in parallel. It further reuses the log forwarding mechanism in primary-backup replication to seamlessly track and forward dirty database tuples and avoids iterative copying costs. To commit a reconfiguration plan in a transactional-safe way, DrTM+B designs a cooperative commit protocol for synchronization of data and state among replicas. To boost the performance during data migration, DrTM+B combines the pre-copy and post-copy schemes to propose a hybrid copy scheme. The live reconfiguration approach can also coexist with fault-tolerance mechanisms of primary-backup replication to provide high availability. Evaluation on a working system based on DrTM+R with 3-way replication using typical OLTP workloads like TPC-C and SmallBank shows that DrTM+B incurs only very small performance degradation during live reconfiguration and provides high availability. Both the reconfiguration time and the downtime are also minimal.
Complex Structure in the Nootka Fault Zone Revealed by Double‐Difference Tomography and a New Earthquake Catalog

We employ an automatic earthquake detection algorithm to seismic waveforms recorded between the years 2000 and 2020 in southwest British Columbia. 32,121 events which possess at least three paired P‐ and S‐wave arrival times are located, compared to 21,538 seismic events in the existing Geologic Survey of Canada catalog. This augmented catalog is employed for double‐difference seismic tomography across Vancouver Island, with particular focus on the Nootka Fault zone (NFZ). The NFZ is a transform boundary that separates the Juan de Fuca and Explorer plates in a zone of distributed left‐lateral strike‐slip faulting. Tomographic results indicate that a double seismic zone exists within the NFZ that parallels Vp/Vs structure typically observed in subduction zones. Specifically, a dipping high Vp/Vs layer is underlain by reduced Vp/Vs material. Structural complexities are revealed by three Mw > 6 events and their aftershocks. The 2004 Mw 6.3 and 2011 Mw 6.4 events are interpreted to reside southeast of the NFZ within the Juan de Fuca plate at depths as shallow as 20 km, and the 2014 Mw 6.6 event is interpreted to reside within oceanic lithosphere of the NFZ at depths >35 km. Vp/Vs structure further indicates that underthrust oceanic lithosphere of the Explorer plate extends to 20 km depth beneath Brooks Peninsula. Our results support the hypothesis that the NFZ represents a structurally independent slice of oceanic lithosphere that exhibits (a) a more northerly trajectory than typically depicted, and (b) increased plate curvature when compared to either the Juan de Fuca or Explorer plates.
Preference for sublingual immunotherapy with tablets in a Spanish population with allergic rhinitis

Abstract Background This study investigated patients' preference for allergy immunotherapy (AIT) administered as either sublingual immunotherapy‐tablets versus monthly or weekly subcutaneous immunotherapy (SCIT) from a Spanish patient perspective. Methods A discrete choice experiment (DCE) consisting of two blocks with eight choice sets in each was constructed to elicit the preferences for AIT. Three attributes were included in the DCE for the mode of administration, including the frequency of administration, the risk of systemic reactions and the co‐payment. Adults and caregivers of children with moderate to severe allergic rhinitis (AR) were included if they were not currently receiving or had not previously received AIT. Results In total, 587 adults and 613 caregivers started the survey. Of those, 579 adults and 611 caregivers completed the survey and were included in the study. Both adults and caregivers had a significant preference for tablets compared with both monthly and weekly injections (p ≤ 0.0001). Furthermore, the respondents showed a significant preference for reducing the risk of systemic reactions. Subgroup analyses showed that caregivers of polyallergic children and female caregivers were significantly less price sensitive when choosing their preferred treatment. Conclusion Our study demonstrated that both adults with AR and caregivers of children with AR prefer daily SLIT‐tablets to SCIT with either a weekly or monthly dose schedule.