Miracle-dz/UniFAR-FTUs huggingface dataset:
Genome-Wide Association Study of Metachronous Colorectal Adenoma Risk among Participants in the Selenium Trial

Abstract Genetic variants related to colorectal adenoma may help identify those who are at highest risk of colorectal cancer development or illuminate potential chemopreventive strategies. The purpose of this genome-wide association study was to identify genetic variants that are associated with risk of developing a metachronous colorectal adenoma among 1,215 study participants of European descent from the Selenium Trial. Associations of variants were assessed with logistic regression analyses and validated in an independent case-control study population of 1,491 participants from the Colorectal Cancer Study of Austria (CORSA). No statistically significant genome-wide associations between any variant and metachronous adenoma were identified after correction for multiple comparisons. However, an intron variant of FAT3 gene, rs61901554, showed a suggestive association (P = 1.10 × 10−6) and was associated with advanced adenomas in CORSA (P = 0.04). Two intronic variants, rs12728998 and rs6699944 in NLRP3 were also observed to have suggestive associations with metachronous lesions (P = 2.00 × 10−6) in the Selenium Trial and were associated with advanced adenoma in CORSA (P = 0.03). Our results provide new areas of investigation for the genetic basis of the development of metachronous colorectal adenoma and support a role for FAT3 involvement in the Wnt/β-catenin pathway leading to colorectal neoplasia. Trial Registration number: NCT00078897 (ClinicalTrials.gov).
The Pólya-Vinogradov inequality for totally real algebraic number fields

(see Montgomery and Vaughan [6]). Here a generalization of these inequalities to totally real algebraic number fields is given. So let K be a totally real field of degree n over Q with ramification ideal d, absolute value of discriminant d = Nd and ring of integers ZK . All constants implied by the -notation depend only on n, if no other dependence is explicitly noted. The nature of the difficulties in making the dependence of the constants on n explicit seems to be purely technical. One has to substitute formula (6) below by a result similar to Lemma 2 of [1]. Let f ⊂ ZK be an ideal, χ a primitive character of the multiplicative group (ZK/f) extended to ZK in the usual manner. Finally, let x ∈ R+ satisfy X := ∏n q=1 xq ≥ 2 and let y ∈ R. By means of Siegel’s summation formula and an additional argument Hinz [3] succeeded in showing
Midair Gestural Techniques for Translation Tasks in Large-Display Interaction

Midair gestural interaction has gained a lot of attention over the past decades, with numerous attempts to apply midair gestural interfaces with large displays (and TVs), interactive walls, and smart meeting rooms. These attempts, reviewed in numerous studies, utilized differing gestural techniques for the same action making them inherently incomparable, which further makes it difficult to summarize recommendations for the development of midair gestural interaction applications. Therefore, the aim was to take a closer look at one common action, translation, that is defined as dragging (or moving) an entity to a predefined target position while retaining the entity’s size and rotation. We compared performance and subjective experiences (participants = 30) of four midair gestural techniques (i.e., by fist, palm, pinch, and sideways) in the repetitive translation of 2D objects to short and long distances with a large display. The results showed statistically significant differences in movement time and error rate favoring translation by palm over pinch and sideways at both distances. Further, fist and sideways gestural techniques showed good performances, especially at short and long distances correspondingly. We summarize the implications of the results for the design of midair gestural interfaces, which would be useful for interaction designers and gesture recognition researchers.
Effects of critical success factors, BIM implementation strategies, and barriers on employer-initiated delays

Abstract Limited research has been performed on the delays caused by employers in building information modelling (BIM)-enabled projects. Thus, this study aimed to determine the effects of critical success factors, BIM implementation strategies, and barriers to employer-initiated delays in BIM-enabled projects. A total of 197 completed questionnaires were collected from various countries and analysed using the structural equation modelling approach. The effects of moderators were studied. The relationships of the success factors to the employer-initiated delays were found to be affected by the BIM implementation strategies and by the BIM barriers. A correlation analysis was conducted between the success factors and the employer-initiated delay factors for the BIM project, emphasising countries or continents lacking delay studies, such as the United States, the United Kingdom, Australia, and China. The key results reveal that BIM implementation strategies have a significant impact on relationships involving management, organisational, and financial planning and team success aspects in employer-initiated delays, also, a significant impact of the BIM barriers on the same relationships has also been confirmed. This study contributes to the development of a comprehensive managerial framework to address employer-initiated delays in BIM-enabled projects.
Changing temporal volatility of precipitation extremes due to global warming

It is of utmost importance to understand how precipitation extremes change due to global warming. Here, we examine the volatility of precipitation extremes by analysing the waiting time distribution between events and the clustering of precipitation extremes. For this we use the ERA5 reanalysis data and high‐resolution simulations with the Community Earth System Model (CESM). We find significant evidence for a power‐law distribution of waiting times between precipitation extremes and of serial clustering of precipitation extremes. This suggests that precipitation extremes do not occur independently from each other. This is in contrast with previous studies which typically assume that precipitation extreme events occur independently from each other. CESM reproduces these properties well. The climate change simulations show that the waiting times between precipitation extremes become shorter and that at the same time the clustering of precipitation extremes increases. Hence, global warming affects the temporal characteristics of precipitation extremes and, thus, precipitation extremes will become more volatile.
Point of care testing to monitor INR control in patients with antiphospholipid syndrome

Patients with antiphospholipid syndrome (APS) typically require lifelong warfarin anticoagulation following a thrombotic event due to a significant risk of recurrent thrombosis. Point of care testing (POCT) to monitor INR is discouraged in patients with APS as interactions between antiphospholipid antibodies and thromboplastin used for INR testing may influence results. Review of INR testing in 36 APS patients showed 87.2% of paired POCT and venous INRs (n = 94) having acceptable variation (≤0.5 difference), and high correlation (r = 0.9) excluding INRs ≥4.8. Six‐month TTR was comparable for APS patients using POCT (57.1% ± 24.8%) to those using venous INR monitoring (59.2% ± 23.2%) (p = 0.66). These results support POCT management of APS but requires further study.
The location of nonactive voice in Albanian and modern Greek

Carlson, G. N. (1981) "Distribution of Free-Choice Any," in Papers from the Seventeenth Regional Meeting, Chicago Linguistic Society, Chicago Linguistic Society, Chicago, Illinois. Chomsky, N. (1986) Barriers, MIT Press, Cambridge, Massachusetts. Davison, A. (1980) "Any as Universal or Existential? " in J. Van der Auwera, ed., The Semantics of Determiners, Croom Helm, London. Hintikka, J. (1977) "Quantifiers in Natural Languages: Some Logical Problems II," Linguistics and Philosophy 1, 135-172. Ladusaw, W. (1979) Polarity Sensitivity as Inherent Scope Relations, Doctoral dissertation, University of Texas at Austin. Linebarger, M. C. (1981) The Grammar of Negative Polarity, Indiana University Linguistics Club, Bloomington, Indiana. Progovac, L. (1988). A Binding Approach to Polarity Sensitivity, Doctoral dissertation, University of Southern California, Los Angeles. Quine, W. V. 0. (1960) Word and Object, MIT Press, Cambridge, Massachusetts. Vendler, Z. (1967) Linguistics in Philosophy, Cornell University Press, Ithaca, New York.
Effect of UV radiation and elevated CO2 on physiological attributes of canola (Brassica napus L.) grown under water stress.

An experiment was conducted to study the effects of solar UV radiation, UV-B, UV-C radiation, and elevating CO2 on some physiological attributes of two canola cultivars (Brassica napus L.) under complete irrigation or limited irrigation in two continuous years. Generally, elevated CO2 increased leaf-soluble carbohydrates, reducing sugars, glucosinolate, and Fv/Fm ratio while carotenoids and soluble protein were decreased due to elevated CO2. In addition, UV radiation decreased leaf-soluble carbohydrates, reducing sugars, chlorophyll, proline, and Fv/Fm ratio and increased UV absorbing pigments, soluble proteins, and glucosinolate.
The Tripod Relationship Between Local Embalmment, Environment and Human Health Implications in Cross River State, Nigeria

The purpose of this paper is to assess the environmental and health implications of local embalmment in Cross River State, Nigeria. The Ex-post-facto research design was adopted for this study. Six embalmment sites from six Local Government Areas were randomly selected across the state from where water and soil samples were taken for laboratory analysis and testing. The environmental impacts, as well as the health implications of local embalmment, were investigated. Multivariate statistical analysis was applied for the physicochemical parameters using a correlation matrix to evaluate factors influencing the groundwater chemistry and sources of pollution in the aquifer of the areas. Some laboratory procedures were also adopted to test the chemistry of the adjoining soils for the impacts of these embalmment chemicals as used by these morticians. A comparative analysis was further done on the different soil samples, the ones directly affected by the immediate mortuary facilities and those away from the facilities. A structured questionnaire made up of twenty items was also administered to the mortuary attendants and residents of the communities and adjoining communities where these embalmment homes are located. Simple percentage and correlation analysis was done to examine the perceived effect of embalmment chemicals on the environment and the health of residents. The results obtained from the laboratory analyses of selected groundwater and soil samples around the mortuary sites studied indicated that formaldehyde, glutaraldehyde, humectants, metals, coli forms, microorganisms, and other contaminants from the mortuary sites have impaired the soil and water quality. It was recommended among others that green embalmment procedures should be encouraged, embalmment services should be located far away from residential areas and water bodies; wastes from embalmment/mortuary services should be sustainably disposed of to avoid these chemicals from contaminating the environment.
WTO Dispute Settlement and the Appellate Body Crisis: Insider Perceptions and Members’ Revealed Preferences

The WTO dispute settlement system is in crisis, endangering the future of the organization. The proximate reason for alarm is the dwindling number of Appellate Body (AB) members, the result of the United States blocking new appointments as the terms of sitting members expire. The AB crisis usually is presented as the U.S. against the world. In this paper, we report on the results of a survey of WTO Members’ perceptions of the AB and the role it plays (should play) and contrast this with Members’ revealed preferences in their use of the dispute settlement system and their intervention in WTO debates about the crisis. The data reveal strong support for the basic design of the dispute settlement system but also that the United States is not alone in perceiving that the AB has gone beyond its mandate.
Lean, Six Sigma and its influence on potential and realized absorptive capacity

Purpose The purpose of this paper is to explore how Lean and Six Sigma’s distinctive practices relate to potential absorptive capacity (PACAP) and realized absorptive capacity (RACAP). The paper seeks to understand which of the practices in Lean Six Sigma are needed to manage absorptive capacity systematically. Design/methodology/approach Partial least square based structural equation modeling (PLS-SEM) was used to test the theoretical model drawing on a sample of 125 manufacturing organizations in Malaysia. In addition to examining direct effects, the study also examines indirect effects using bootstrapping method to identify possible mediation effects proposed in the model. Findings The results explain that Lean’s social practices (LSP), Six Sigma’s roles structure (RS) and structured improvement procedure (SIP) positively influence potential absorptive capacity (PACAP). Meanwhile LSP, RS and focus on metrics (FOM) positively influence realized absorptive capacity (RACAP). SIP was found to influence RACAP through PACAP. The analysis reveals the combination of Lean Six Sigma practices that are required in managing PACAP and RACAP differentially. Research limitations/implications The study is only confined to manufacturing industries in Peninsular Malaysia. Data collected were cross-sectional in nature. The application of Lean Six Sigma and how it influences absorptive capacity may get sturdier across time, and this may change the effect toward sustainability of firm’s competitive advantage. A longitudinal study may be useful in that context. The study also makes specific recommendations for future research. Practical implications The results of this study can be used by Lean Six Sigma practitioners to prioritize the implementation of Lean Six Sigma practices to develop absorptive capacity of the organization through PACAP and RACAP, which needs to be managed differentially as they exert differential outcomes. This would enable organizations to tactfully navigate and balance between PACAP and RACAP in accordance to business strategies and market conditions. Originality/value Absorptive capacity in Lean and Six Sigma context has largely been studied as a unidimensional construct or used as a grounding theoretical support. Therefore, understanding the multidimensionality through PACAP and RACAP provide insights on how to enhance and maneuver absorptive capacity through Lean Six Sigma systematically. The findings may pave the way for future research in enhancing the current knowledge threshold in Lean Six Sigma.
Sequentiality in Real Number Computation

1 Introduction 31.1 Classes of Numbers . 31.1. 1 Countable Sets of Numbers: N, Z and Q . 41.1. 2 Uncountable Sets of Numbers: R and C . 71.1. 3 Summary . 111.2 Computation on Countable Sets of Numbers . 121.2. 1 Natural Numbers . 131.2. 2 Rational Numbers . 161.3 Computation on Real Numbers . 171.3. 1 Floating Point Representation . 171.3. 2 Cauchy Sequence Representation . 201.4 Summary . 262 Technical Background 292.1 λ-calculus . 292.2 Domains for Computation . 332.3 PCF . 372.3. 1 Operational Semantics of PCF . 392.3. 2 Denotational Semantics of PCF . 402.3. 3 The Necessity of Parallel Operators . 412.4 Sequentiality . 48i
Porcine circovirus type 2 and its associated diseases in southwestern Nigeria: Farmers’ perception and level of awareness

Objective: Porcine circovirus type 2 (PCV2) is one of the most important causative agents of swine diseases that pose a global economic threat. Presently, there is little or no information on the perception and awareness of PCV2 and its associated effects among pig farmers in Nigeria. Therefore, this research was carried out to describe pig farmers’ views, awareness, and likely impact of PCV2 and its associated postweaning multisystemic wasting syndrome (PMWS) on pig production in the southwestern region of Nigeria. Materials and Methods: A cross-sectional survey of pig farmers in Oyo and Ogun states, Southwest Nigeria, was carried out with the help of a self-administered questionnaire. Results: A total of 111 farms out of the 385 required took part in the study, resulting in a total response rate of 28.8%. 89 (79.2%, 95% CI = 70.8–85.8) pig farmers who participated were unaware of PCV2, while 46 (41.4%, 95% CI = 32.7–50.7) had heard about PMWS. The level of awareness was generally poor, with an average score of 1.43 (SD ± 1.25; 23.9%). Only 23% (25/111) of the participants had a high level of awareness. To promote awareness about PCV2/PMWS, participants’ most preferred sources of information were seminars, extension services (especially by veterinary and agricultural extension officers), social media (WhatsApp and YouTube), and mobile telephone (through calls or text messages). Conclusions: The present study showed a gap in the level of farmers’ awareness about PCV2/PMWS, and to bridge the gap, more scientific-based evidence is needed to promote targeted educational programs and policy formulations. Also, with the dearth of information about PCV2, it is necessary to determine its prevalence and the characteristics of the virus possibly circulating within the swine herds in Nigeria.
“If You Can Just Break the Stigma Around It”: LGBTQI+ Migrants’ Experiences of Stigma and Mental Health

Migrants, that is people who experience forced displacement or move based on being lesbian, gay, bisexual, trans, two-spirit, queer, and intersex (LGBTQI+), experience increased trauma and stigma when compared to heterosexual and cisgender people. The aim of this paper is to highlight LGBTQI+ migrants’ experiences of health and social care encounters in Canada. Gadamerian hermeneutics and an intersectionality lens was used to understand LGBTQI+ migrants’ experiences. A total of 16 semi-structured individual interviews were conducted with LGBTQI+ migrants. Themes of stigma and discrimination were identified as (1) “I never went back”: Stigma as an exclusionary experience, (2) “Is [your country of birth] really that bad”: Fear, safety, and cultural stigma, and (3) “The circle … is not going to fix my life”: LGBTQI+ migrants’ call for affirming care. Results suggest that health and social care practices are stigmatizing and discriminatory which negatively impacts LGBTQI+ migrant mental health. Salient practices for promoting mental health included affirming LGBTQI+ identities and orientations through health and social care practices that are culturally safe as well as trauma and violence informed.
Identity Management Strategies, Sports Fandom and Para-social Relationships in Cricket Fans

The current research investigated the relationship among identity management strategies, sports fandom and para-social relationships in cricket fans. It was hypothesized that there would be a relationship among identity management strategies, sports fandom and para-social relationships while sports fandom would mediate between identity management strategies and para-social relationships. By employing a cross-sectional correlational research design, a sample of (N = 120) cricket fans with an age range of (18-30) years (M = 22.34, SD = 2.62) was recruited through non-probability purposive sampling technique. Study variables were assessed through the Basking in Reflected Glory Scale (Spinda, 2009), Cutting off Reflected Failure Scale (Spinda, 2009), Sport Spectator Identification Scale (Gwinner & Swanson, 2003) and Celebrity-Persona Identification Scale (Brown & Bocarnea, 2007). Results revealed a positive association among all study variables while sports fandom was found to partially mediate identity management strategies and para-social relationships in cricket fans. Findings have interdisciplinary implications within the fields of group dynamics; sports sciences, sociology and social psychology as it is a research-based, empirical addition to existing indigenous literature regarding cricket that is the most popular game in the country. Also, it highlights the respective association and predictive value of the study variables which can be further investigated across other games, as well as across disciplines.
Human Governance Index of Manufacturing Sector of Shariah Compliant Companies in Malaysia: A Preliminary Analysis

Human Governance refers to the governors’ commitment to improve employees’ values and ethical behaviour in the organization. Humans are capital asset and key driver to a successful organisation. The objectives of the study are to explain the development of human governance index and discuss the findings of human governance index when applied to 68 Shariah-compliant companies in the manufacturing sector. Previous study used primary and secondary data. Thus, this study will combine the indices of Human Governance from previous study and will develop a more comprehensive checklist using secondary data. Human Governance Index of this study comprises 37 items which are made up of four (4) main components which are (1) BOD Leadership - which is measured by i) BOD Job Experience Index, (ii) BOD Educational Background Index, (iii) BOD Educational Level Index, (iv) BOD Age Index, (v) BOD Gender Diversity Index; (2) Level of Integrity Index; (3) BOD Quantity of Training Index; and (4) Quality of Internal Control System Index. The index has been validated by panel experts and inter-rater consistency was also conducted. The index was then used to measure the Human Governance Index of 68 Shariah-compliant companies’ annual reports for the year 2019. 68 Shariah-compliant companies are from manufacturing companies which comprise 25 consumer products, 3 healthcare, and 40 industrial products. The results of this study revealed that consumer product sector has the highest items compared to industrial product and healthcare sectors. BOD job experience index has the highest mean of 92.9% indicates that BOD has more than 10 years’ experience and BOD gender diversity index has the lowest mean of 17.6% which comprises female. Human governance Index can be used to assist companies to improve their human capital who are important assets to the company and have been proven to increase performance of companies if they are better managed.
Heavy drinking in Brazil: results from the 2013 National Health Survey

Abstract: Objective: to describe the prevalence of heavy drinking in the Brazilian population, according to sociodemographic and health-related characteristics, in 2013. Methods: a descriptive study was conducted with National Health Survey (PNS) data regarding heavy drinking in the 30 days prior to interview, among individuals aged≥18 years. Prevalence and 95% confidence intervals (95%CI) were estimated. Results: overall prevalence was 13.7% (95%CI 13.1; 14.2%). It was higher among men (21.6%; 95%CI 20.7; 22.5%) compared to women (6.6%; 95%CI 6.1; 7.1%). Higher prevalence was found among young adults (18-29 years: 18.8%; 95%CI 17.5; 20.0%), those with black skin color (16.6%; 95%CI 14.9; 18.4%), occasional smokers (35.2%; 95%CI 30.4; 40.0%), individuals who rated their health as good or very good (15.6%; 95%CI 14.9, 16.3%) and with no reported morbidities. Conclusion: prevalence of heavy drinking showed notable differences according to sociodemographic and health-related characteristics.