Miracle-dz/UniFAR-FTUs huggingface dataset:
Emulsification and Foaming Properties of Locust Bean (Parkiabiglobosa) and Pigeon Pea (Cajanuscajan) Seed Flours and their Protein Isolates

Emulsification and foaming properties of Locust bean (Parkia biglobosa) and pigeon pea (Cajanus cajan) seed flours and their protein isolates was investigated in this study. Also, their protein isolates were profiled for amino acid status. Some of the flour and protein isolate samples were heat-treated at 85 °C for various times. The functional properties results showed that pigeon pea was rich in most of the properties except water and oil absorption capacity. Pigeon pea flour has higher bulk density (0.82g/cm3), loose density (0.63g/cm3), emulsion stability (73.38%), foaming stability (79.81%) and least gelation (14.37%) than locust bean flour. Locust bean flour has higher swelling capacity (2.17g/ cm3), water absorption capacity (3.76ml/g), oil absorption capacity (2.69ml/g), emulsification (33.68%) and foaming capacity (20.68%) than pigeon pea flour. Pigeon pea protein isolate treated at 85 °C for 10 minutes was a better emulsifier and foaming agent than Locust bean protein isolate with the same heat treatment. Protein solubility of pigeon pea was higher at all temperatures (60-90°C) than Locust bean. Pigeon pea protein isolate treated at 85 °C for 10 minutes gave higher values of both essential and non-essential amino acids showing that pigeon pea would be more useful in food formulations involving both low and high pH.
The Role of Apoptosis and Reactive Oxygen Species in Varicocele-Associated Azoospermia

Background: The exact mechanism of impaired testicular function in patients with varicocele is not yet known. There is an increasing body of evidence pointing towards the role of reactive oxygen species (ROS) and apoptosis in the pathogenesis of varicocele related subfertility. Objective: The aim of the study is to study the role of apoptosis and reactive oxygen species in varicoceleassociated azoospermia. Methods: Testicular tissue biopsy was obtained from 40 azoospermic infertile patients with varicocele and 40 infertile obstructive azoospermic patients. Caspase 3 level was determined by ELISA and malondialdehyde (MDA) level by colorimetry. Results: Testicular MDA and caspase 3 level were significantly higher in the varicocele group compared to the control group. Increasing levels of MDA and caspase 3 were associated with higher varicocele grades. There was a statistically positive correlation between testicular caspase 3 and MDA levels in the varicocele group. Conclusion: The present study documented the role of reactive oxygen species (ROS) and regulators of apoptosis in the pathophysiology of infertility in patients with varicocele-associated azoospermia.
Multi-Threshold Based Low Power Dual Edge Triggered Flip-Flop

Digital circuit design is streamlined process used to improve the performance of a circuit for a particular application. Fast speed, minimum power dissipation and less area are the desirable characteristics of a digital circuit, in general. To meet a particular standard of speed, a compromise in power dissipation and speed is required. Timing elements such as Flip-flop are used as clock generators. These consume almost 50% of the total system power. In this paper, a low power dual edge triggered D flip-flop is proposed. The circuit complexity is reduced by using less number of transistors. Multi-threshold technique is employed to reduce the power dissipation of the proposed circuit.
Complications Following Prostate Biopsy: A Single Centre Five Year Review

Background: Though prostate biopsy is generally a safe procedure, it can be associated with complications. It is important to document the complication rates and identify potential risk factors for these complications. The aim of this study was therefore to investigate the complication rates following prostate biopsy at the Lagos State University Teaching Hospital Ikeja Lagos Nigeria over a 5 year period from January 2012 to December 2016. Patients and Methods: This was a retrospective study in which the clinical records of all the patients who had prostate biopsy at the Lagos State University Teaching Hospital Ikeja, Lagos Nigeria over a 5 year period between January 2012 and December 2016 were retrieved and analyzed. Results: The clinical records of a total of 258 patients were available for review. The mean age was 68.2years (range 45 to 81years). The mean and median PSA values were 560ng/ml and 57ng/ml respectively (range 2.05 to 15,400ng/ml). The prostate biopsy was transrectal and digitally guided in all cases. All the patients had empirical intravenous prophylactic antibiotics with intravenous ciprofloxacin 500mg stat and were discharged on oral ciprofloxacin 500mg bd and oral metronidazole 400mg tds for one week. All the patients had a caudal block. One hundred and seventeen (45.3%) had a comorbidity. The mean prostate size was 109gms (range 16 – 146gms). The size of the trucut needle used was size 16 in 121 patients (46.9%) and size 18 in 125 patients (48.4%). The mean number of biopsy cores taken was 10 (range 4 to 15). The histological diagnosis was carcinoma of the prostate in 154 patients (59.7%) and benign prostatic hyperplasia in 100 patients (38.8%). Twenty four patients (9.3%) had complications. The complications were sepsis (3.1%), rectal bleeding (2.3%), haematuria (2.3%) and acute urinary retention (1.6%). Thirteen patients needed hospitalization (5%). There was no mortality. The incidence of sepsis was statistically significantly higher with increasing the number of cores taken (p=0.000), but there was no significant difference in the incidence of sepsis with the size of the trucut needle used (p= 0.299) or the presence of morbidity (p = 0.503). Conclusion: Though the complication rates following prostate biopsy remain low, increasing number of prostate cores taken is a risk factor for adverse events. We therefore recommend reducing the number of prostate cores taken in patients with advanced prostate cancer with high tumour volume in order to further reduce the risk of prostate biopsy complications in our environment.
An Investigation of Cultural Sensitivity of Nurses in Foreign Patient Care: A Descriptive Study in Turkey. -

Background: The objective of this study is to identify the cultural sensitivity of foreign nurses and to state the factors effecting the situation. Methodology: The sample of this study involves 82 nurses who participated to this study voluntarily and work in a nursing and communication with foreign patients of a private hospital in Turkey. The data was collected by the researchers by using ‘Nurse Introduction Form’ and ‘Intercultural Sensitivity Scale (ISS). Results: Results of this study are as follows; it has been shown that the intercultural sensitivity level is at medium-level (2.71±0.48). The results about intercultural sensitivity have shown that the most important factors regarding the intercultural sensitivity of the nurses are respecting the cultural differences and self-esteem in intercultural interaction. It has also been shown that the nurses who have been to exchange studies and taken cultural nursing courses are have higher intercultural sensitivity than others. Moreover, it has also been stated that as the years of experience increased, the intercultural sensitivity got lower among the nurses. Conclusions: As a result of this study, it has been shown that the intercultural sensitivity level is at medium-level.
Transport Control Protocol for Cognitive Radio

— The rapid demand for wireless communication networks in the last few decades has lead to spectrum scarcity, Hence there is need of efficient spectrum utilization is occurs. Cognitive radio is a novel technology which improve the spectrum resource utilization and allows a cognitive radio transceiver to detect and sense the available spectrum. Cognitive Radio (CR) networks allow users to transmit in the licensed spectrum bands, without degrading the performance of the Primary Users (PUs). Routing in CRN is a challenging task due to the variations in spectrum availability with time and periodic spectrum sensing undertaken by the CR users. In this paper we investigate the effect of TCP in CR ad hoc network environment and proposes multipath routing protocol, that uses on-demand distance vector routing, called Ad hoc On-demand Multipath Distance Vector (AOMDV) Routing Protocol. We analyze its performance using Network simulator (NS-2) software tool. Simulation gives effective result of cognitive radio ad hoc networks and analyzed the parameter delay, throughput and energy.
CONNECTION BEHAVIOR IN COMPOSITE PROFILED STEEL SHEET DRY BOARD (PSSDB) SYSTEM

This paper studied the behavior of the connections in the composite Profiled Steel Sheet Dry Board (PSSDB) system. The PSSDB is a light weight composite panel comprised of a profiled steel sheet PSS and cement board as dry board connected together by either mechanical fasteners or by epoxy adhesive resin. Ten push-out specimens with different size, shape, thickness of dry board, and types of connections were carried out. The ultimate load, the load slip relationship, and modes of failure were observed. The results showed that the samples connected by epoxy adhesive resin can sustain load greater than that connected by mechanical fasteners up to 76%, and the ultimate load affected by the thickness of dry board. The capacity of connecter (self drillingself tapping screw with 4.2 mm diameter) is about 1.736 kN/screw. This value increased by about 20% with the increase in dryboard thickness to double (from 8 mm to 16 mm). The Ultimate load sustained by the specimens connected by using epoxy adhesive resin is about 37 kN/m and 137 kN/m for the DB connected to ribs and trough sides of PSS, respectively. These values increased by about 14% with the increase in dryboard thickness to double.
Clinical isolates of Pseudomonas aeruginosa cultured from patients admitted to the Intensive Care Unit (ICU)

Ninety four clinical isolates of Pseudomonas aeruginosa cultured from patients admitted to the Intensive Care Unit (ICU) (N= 37) and Otolaryngology (ORL) (N= 57) during one year (2001-2002) at the Rabta hospital (Tunisia) have been investigated by using serotyping, pyocintyping, drug susceptibility, M13-PCR and PFGE typing. Result shown that most of the isolates at the ICU belonged to serotype O:12 (11/37) that showed high resistance to commonly used antimicrobials ( -lactamins, aminosids, and quinolone) and a predominance for pyocinotype P10. Despite the frequent occurrence of identical serotypes and pyocinotypes, most of the isolates represent unique RAPD-M13 genotype (88/94). PFGE typing detected three distinct clusters amongst the O12 isolates, suggesting a clonal relatedness among multiresistant O12 isolates. This study illustrates the importance of phenotypic and genotypic epidemiological surveillance of predominant O12 serotype clones in such service in local hospital.
A Study on Vehicle Ranking and Comparing System

: With the emergence of the deep web, searching web databases in domains such as Vehicles, Real estate, etc has become a routine task. One of the problems in this context is ranking the results of a user query. The mainstay of this project is to provide an automated ranking system for automobiles based on user feedback. The current sorting-based mechanisms used by Web databases do not perform such ranking. They do not perform automated ranking instead user has to manually identify based on the ratings.
Clinical, pathologic, and genomic profiles of exceptional responders to anti−PD1 therapy in renal cell carcinoma.

625 Background: Previous studies have correlated response to PD−1 blockade with PD−L1 over−expression, as well as cell−mediated immune transcripts). However, factors associated with long−term, durable response to nivolumab in patients with RCC have not yet been elucidated. To better understand these factors, we conducted a study to characterize the two extremes of response to therapy – exceptional responders who had durable, complete response and patients who had primary refractory disease. Methods: Patients with durable, complete response (“exceptional responders”) (n=4) and primary refractory disease (n=3) were analyzed. Immunohistochemical staining for PD−L1, CD8 and FOXP3, whole−exome sequencing and quantitative RNA expression profiling was performed and correlated with clinical outcomes. Results: Exceptional responders had trends toward greater CD8+ lymphocyte infiltrate (126.7 vs 28.8 lymphocytes/hpf), higher number of somatic mutations (67 vs 35 somatic mutations/genome), and higher number of predi.
Clinical correlation of oxidant-antioxidant balance and Vitamin D in asthmatic patients

Asthma is a chronic inflammatory lung disease that results in airflow limitation, hyperreactivity, and airway remodeling. There is strong evidence that an imbalance between the reducing and oxidizing systems lead more oxidative state in asthma. Endogenous and exogenous reactive oxygen species and reactive nitrogen species play a major role in the airway inflammation and cause of severe pathogenesis. Atmospheric pollution, dietary changes, changes in allergen load, improvements in health and hygiene, and lifestyle changes have all been proposed for asthma. It has been observed, poor antioxidant rich nutrition and lack of Vitamin D are also a common cause for pathogenesis of asthma. Vitamin D as lung immunomodulator and Vitamins A, C, E as antioxidants improves the complications of inflamed airflow in asthma. In this review study, we will summarize the current knowledge and discuss the current pharmacological strategies regarding the role of antioxidant activity and Vitamin D in favor to regulate and prognose to inflammatory asthma.
Correlation of Subclinical Hypothyroidism with Dyslipidemia in Perimenopausal Women

Introduction: Although overt hypothyroidism with its accompanying dyslipidemia is widely recognized as a risk factor for atherosclerosis and cardiovascular disease but now subclinical hypothyroidism emerged as an independent risk factor for aortic atherosclerosis and myocardial infarction in women. Subclinical hypothyroidism is characterized by dyslipidemia most commonly in elderly females but perimenopausal females are also at higher risk. There are limited studies on subclinical hypothyroidism in India on perimenopausal women which is done in our study. Objective: The objective of the study was to find the correlation of dylipidemia with subclinical hypothyroidism in perimenopausal women in central India. Material and Methods: The study was conducted at department of medicine in Gandhi Medical College and Hamidia Hospital, Bhopal for one year from January 2015 to December 2015. It was an observational cross-sectional study. Females of 35-45 years of age group with raised TSH and normal T3 and T4 values were included in the study. 66 females patients of SCH were included in this study and subdivided in two groups according to their TSH values as group1 (5.5-10) and group2 (>10) and their fasting lipid profile and thyroid samples were measured. Results: Significant results were observed in different parameters among both the groups of SCH. Total cholesterol, Triglycerides, LDL-cholesterol, TC/HDL ratio and LDL/HDL ratio was highly significant (<0.01) in both groups but HDL-cholesterol and TSH levels were not significant (>0.05) in the two groups of SCH. Group having TSH (>10μIU/ml) have the higher risk of developing atherosclerosis as compared to females with TSH (5.5-10μIU/ml). Total cholesterol, Triglycerides, LDL, TC/HDL ratio and LDL/HDL ratio were positively correlated with TSH values in both the groups of perimenopausal females whereas the HDL cholesterol had no correlation with TSH values among SCH perimenopausal females. Conclusion: This study showed that perimenopausal women with subclinical hypothyroidism were characterized by dyslipidemia in the form of increased TC, TG and LDL. SCH groups having TSH (>10μIU/ml) have the higher risk of developing atherosclerosis as compared to perimenopausal females with TSH (5.5-10μIU/ ml). TC/HDL ratio and LDL/HDL ratio were also higher in both SCH group suggesting the future development of cardiovascular disease in these females.
Antioxidant Properties of Ocimum basilicum Leaves Extract: An in vitro study

Free radicals are considered as the chief causative factor in the progression of various diseases such as diabetes mellitus and cancer. In order to scavenge superfluous free radicals and maintain the human body, the consumption of dietary antioxidants is essential. Synthetic antioxidants have toxic effects to some extents. Therefore, the intake of natural antioxidants preferentially from plant sources is essential. Ocimum basilicum L (Lamiaceae), a medicinally important plant commonly known as “Holy basil” have been reported to possess a wide range of pharmacological properties. In the present study, an attempt has been made to analyze the antioxidant properties of Ocimum basilicum leaves extract. Phytochemical analysis of the leaves extract revealed the presence of phenols, alkaloids, flavonoids, glycosides, saponins, tannins, phytosterols and triterpenoids. The total phenolic and flavonoid content were found to be 284.72 ± 1.44 mg Gallic acid equivalent and 43.65 ± 0.21 mg quercetin equivalent respectively. The carbohydrate and protein content was found to be 8.15 ± 0.27 mg /g and 4.2 ± 0.32 mg /g of the leaves extract respectively. The leaves extract was found to be antioxidant in nature which is evident from DPPH, ABTS, NO, Superoxide radical scavenging assays. At a concentration of 1000μg/ml, the extract significantly scavenged 84% of DPPH radicals (IC50=586.3 μg/ml) and 79% ABTS radicals (IC50=727.9 μg/ml). O. basilicum leaves extract exhibited a maximum of 81% superoxide scavenging activity (IC50= 604.2 μg/ml) at a concentration of 1000 μg. The extract exhibited a maximum of 83% NO scavenging potential (IC50= 652.60 μg/ml). Thus it can be concluded that Ocimum basilicum leaves extract can be used for the treatment of free radical mediated diseases such as diabetes mellitus and cancer.
Nutraceuticals profiling of queen and king varieties of pineapple (Ananas comosus) (Pineapple)

Locally available two varieties of pineapple (Ananas comosus) i.e. King and Queen were evaluated for their comparison of selected biochemical parameters. The biochemical parameters studied in peel, pulp and juice of fruit. The enzymatic antioxidant studied were Polyphenol oxidase, Catalase, Ascorbate peroxides, Guaicol peroxidase whereas the non-enzymatic parameters studied were Total flavonoids, Total phenol, Carotenoids and Alkaloid. The minerals studied were Phosphorus, Magnesium, Potassium, Sodium, and vitamins were thiamine, Folic acid, Riboflavin, Vitamin C. All were maximum in peel, pulp and juice of King and minimum in Queen. In general, King was found to have more antioxidant than Queen. Though pulp and juice is generally consumed but peel of Queen and king pineapple studied were also found to have significant amount of antioxidant in them.
J Gynecol 2016, 1(4): 000123

Monoclonal antibodies were generated against a synthetic peptide corresponding to N1-29 sequence located in the extracellular domain of human GnRH (gonadotropin-releasing hormone) receptor. Among the fourteen established monoclonal antibodies GHR103 and GHR106 were shown to have the highest affinity (Kd≈2 x10-9 M) to the synthetic peptide as well as to the native GnRH receptor in cancer cell extract. Through immunoglobulin gene analysis, both GHR103 and GHR106 were shown to have identical DNA sequences in both heavy and light chains of IgG1 subclass. GHR106 was shown to be highly specific to N1-29 peptides derived from GnRH receptor of human and monkey, but not to that from mouse. Immunohistochemical studies were performed with as many as 30 different cancer cell lines and were found to positively stain more than 80% of cases, irrespective of their tissue origins. Consistent results were obtained with other assays such as Western Blot, indirect immunofluorescence and RT-PCR. Similar to GnRH decapeptide antagonist, Antide, GHR106 was shown to induce apoptosis and inhibit cell proliferation to culturing cancer cells by TUNEL and MTT assays, respectively. Furthermore, GHR106 was shown to induce lysis of cancer cells in culture through complement-dependent cytotoxicity reactions (CDC) which are absent with GnRH peptide analogs. Humanized forms of GHR106 (hGHR106) were generated and found to be bioequivalent to murine GHR106 (mGHR106) as well as to GnRH antagonist, Antide in terms of their respective binding affinity and biological properties. Widespread expressions of GnRH receptor among various human cancer, hGHR106 can be bioequivalent alternative to GnRH decapeptide analogs and can serve as the antibody-based anti-cancer drugs of much longer half-life as compared to that of GnRH decapeptide analogs (days vs. hrs.). Furthermore, humanized GHR106 can be long-acting substitute to GnRH decapeptide analog for numerous gynecological indications in fertility regulations and women health.
Determination of the Effect of Tillage on Soil Resistance to Penetration. A Study of South-East Agricultural Soils

The effect of tillage on soil resistance to penetration was determined on three agricultural soil types (clay-loam, sandy-loam, and sandy-clay) in south-east Nigeria. Four tillage treatments namely: plough, harrow ridger and zero tillage were used for the study under twelve (12) arbitrary depth ranges (0 to 600mm). Results obtained showed that clay-loam had its highest penetration resistance at depth range of 350-400mm with average resistance of 14.3kg/mm 2 for plough, 10.4kg/mm 2 for harrow, 7.9kg/mm 2 for ridger and 13.3kg/mm 2 for zero tillage. However, at the end of 600mm depth, the overall average penetration resistance was found to had improved from 9.84kg/mm 2 of zero tilled soil to 8.08kg/mm 2 , 6.48kg/mm 2 and 4.23kg/mm 2 with plough, harrow and ridger respectively.Sandy-loam gave its highest penetration resistance of 12.3kg/mm 2 , 10.5kg/mm 2 , 7.2kg/mm 2 and 12.8kg/mm 2 for plough, harrow, ridger and zero tillage respectively at depth range of 250-350mm. But at the end of 600mm depth, the overall mean penetration resistance reduced from 8.43kg/mm 2 of zero tilled soil to 7.22kg/mm 2 for plough, 5.26kg/mm 2 for harrow and 3.33kg/mm 2 for ridger. Finally, sandy-clay showed its highest resistanceto penetration at depth of 300-400mm with average resistance of 13.3kg/mm 2 for plough, 11.5kg/mm 2 for harrow, 7.4kg/mm 2 for ridger and 13.8kg/mm 2 for zero tillage. At the end of 600mm depth, the overall mean penetration resistance was brought down from 8.46kg/mm2 of zero tilled soil to 7.22kg/mm 2 , 5.26kg/mm 2 and 3.83kg/mm 2 for plough, harrow, and ridger respectively.