Miracle-dz/UniFAR-FTUs huggingface dataset:
Extragalactic sources towards the central region of the Galaxy

We have observed a sample of 64 small-diameter sources towards the central -6° < l < 6°, -2° < b < 2° of the Galaxy with the aim of studying the Faraday rotation measure near the Galactic Centre region. All the sources were observed at 6- and 3.6-cm wavelengths using the ATCA and the VLA. 59 of these sources are inferred to be extragalactic. The observations presented here constitute the first systematic study of the radio polarization properties of the background sources towards this direction and increase the number of known extragalactic radio sources in this part of the sky by almost an order of magnitude. Based on the morphology, spectral indices and lack of polarized emission, we identify four Galactic H II regions in the sample.
Generation and integration of hair follicle-primed spheroids in bioengineered skin constructs

Skin is a complex organ made up of different cell layers, appendages, connective tissues, and immune repertoires. These different components interact extensively to maintain the overall functions of the integumentary system. In particular, appendages such as hair follicles critically contribute to the skin’s function in thermoregulation, sensory perception, and homeostatic regeneration. Despite a strong need for better skin regenerative therapeutics, efforts to bio-engineer highly functional appendage-containing human reconstituted skin in vitro have not yielded much success. Here, we report methods in generating and incorporating hair follicle-primed heterotypic spheroids into epidermal-dermal skin constructs that induced invaginating outgrowths with follicle-like organization and lineage gene expression. By co-culturing epithelial keratinocytes (KCs) with dermal papilla (DP) cells in low attachment plates, we established the media and culture conditions that best supported the viability, signalling and remodelling of the cell aggregates to form 3D KC-DP spheroids with the expression of both DP inductiveness and hair follicle lineage genes. We show that long-term growth and maturation of KC cells in these spheroids was supported by incorporation into epidermal-dermal constructs but not in scaffold-less media. When cultured, the bio-fabricated constructs developed invaginations from the integrated spheroids with follicle-forming potential. The generation of these constructs is a step towards the development of functional hair-bearing skin mimetics.
Development and Validation of a Brief Version of the European Bullying and Cyberbullying Intervention Project Questionnaires (EBIP-Q and ECIP-Q).

BACKGROUND In order to prevent school bullying and cyberbullying, brief measurement instruments with adequate psychometric properties are required. The objective of this study was to develop a combined reduced version of the European Bullying Intervention Project Questionnaire (EBIP-Q) and the European Cyberbullying Intervention Project Questionnaire (ECIP-Q) for its use in the screening of bullying-related behaviors at school. METHOD The sample consisted of 1777 students, between 14 and 18 years of age (M = 15.71; SD = 1.26), of which 54.1% were female. RESULTS The resulting reduced version presents adequate psychometric properties with reliability coefficients between ω = . 72 and ω = . 82. Factor analyses indicate that both bullying and cyberbullying are structured around two factors: victimization and aggression. The correlations between the scores of the original version and the reduced version were adequate. Bullying and cyberbullying was associated with different indicators of socioemotional adjustment. CONCLUSIONS The European Bullying and Cyberbullying Intervention Project Questionnaire Brief version (EBCIP-QB) seems to be brief, useful, and have adequate psychometric properties for the assessment of bullying and cyberbullying in Spanish adolescents.
A capability perspective on sustainable employability: A Dutch focus group study on organizational, work and personal conversion factors

Objective In the field of work, there is a shift towards more value-based approaches to study the sustainable employability of the present-day worker. The capability approach offers a value based and innovative conceptualisation and framework of sustainable employability characterized by contextuality, normativity and diversity. The capabilities of Dutch employees have been established and validated, yet it is not known which conversion factors on a personal, work and organizational level enable employees to achieve value in work in different Dutch occupational sectors. Methods Our qualitative approach included seven focus groups in different occupational sectors including elderly care, higher education, insurance work, facility management and the oil-, car- and chemical industry. Each focus group included 5–11 participants and took approximately one and a half hour. A qualitative content analysis was used to analyse the data, by combining deductive and inductive coding respectively. Deductive coding involved assigning themes to the conversion of resources into capabilities at the organizational, work and personal level. Results On the organizational conversion level, important themes were cultural aspects, power relations, shortage of personnel and policies for self-management. On the work conversion level, social contacts, communication and workload, tasks and schedules were identified. Social contacts were described as a work value in itself, but also conditional for achieving other work values. On the personal conversion level, experienced work stress, motivation and the ability to achieve values informally within the company. Conclusion From our findings it follows that focus groups are sensitive to identify conversion factors on all three levels of conversion. In addition, companies and their employees might effectively increase work capabilities by being sensitive to all three conversion levels simultaneously. Further research is necessary to study the effect of a capability-based intervention at the work floor.
Extended colored Zee-Babu model

We study the extended colored Zee-Babu model introducing a vectorlike quark and singlet scalar. The active neutrino mass matrix and muon anomalous magnetic moment, which can be fitted to experimental data satisfying the constraints from the flavor-changing neutral current, are analyzed. Then, we discuss the constraint from ${h}_{\mathrm{SM}}\ensuremath{\rightarrow}\ensuremath{\gamma}\ensuremath{\gamma}$, the implication of an exotic diphoton resonance as a signature of the model, and the stability of the scalar potential. In addition, we discuss the signature of our model via vectorlike quark production.
Heart failure with preserved ejection fraction and non‐alcoholic fatty liver disease: new insights from bioinformatics

Heart failure with preserved ejection fraction (HFpEF) and non‐alcoholic fatty liver disease (NAFLD) are related conditions with an increasing incidence. The mechanism of their relationship remains undefined. Here, we aimed to explore the potential mechanisms, diagnostic markers, and therapeutic options for HFpEF and NAFLD.
Adult male birds advance spring migratory phenology faster than females and juveniles across North America

Advances in spring migratory phenology comprise some of the most well‐documented evidence for the impacts of climate change on birds. Nevertheless, surprisingly little research has investigated whether birds are shifting their migratory phenology equally across sex and age classes—a question critical to understanding the potential for trophic mismatch. We used 60 years of bird banding data across North America—comprising over 4 million captures in total—to investigate both spring and fall migratory phenology for a total of 98 bird species across sex and age classes, with the exact numbers of species for each analysis depending on season‐specific data availability. Consistent with protandry, in spring (n = 89 species), adult males were the first to arrive and immature females were the last to arrive. In fall (n = 98), there was little difference between sexes, but adults tended to depart earlier than juveniles. Over 60 years, adult males advanced their phenology the fastest (−0.84 days per decade, 95 CrI = −1.22 to −0.47, n = 36), while adult and immature females advanced at a slower pace, causing the gap in male and female arrival times to widen over time. In the fall, there was no overall trend in phenology by age or sex (n = 57), driven in part by high interspecific variation related to breeding and molt strategies. Our results indicate consistent and predictable age‐ and sex‐based differences in the rates at which species' springtime phenology is shifting. The growing gap between male and female migratory arrival indicates sex‐based plasticity in adaptation to climate change that has strong potential to negatively impact current and future population trends.
Clinical correlates of early onset antipsychotic treatment resistance

Background: There is evidence of heterogeneity within treatment-resistant schizophrenia (TRS), with some people not responding to antipsychotic treatment from illness onset and others becoming treatment-resistant after an initial response period. These groups may have different aetiologies. Aim: This study investigates sociodemographic and clinical correlates of early onset of TRS. Method: Employing a retrospective cohort design, we do a secondary analysis of data from a cohort of people with TRS attending the South London and Maudsley. Regression analyses were conducted to identify the correlates of the length of treatment to TRS. Predictors included the following: gender, age, ethnicity, problems with positive symptoms, problems with activities of daily living, psychiatric comorbidities, involuntary hospitalisation and treatment with long-acting injectable antipsychotics. Results: In a cohort of 164 people with TRS (60% were men), the median length of treatment to TRS was 3 years and 8 months. We observed no cut-off on the length of treatment until TRS presentation differentiating between early and late TRS (i.e. no bimodal distribution). Having mild to very severe problems with hallucinations and delusions at the treatment start was associated with earlier TRS (~19 months earlier). In sensitivity analyses, including only complete cases (subject to selection bias), treatment with a long-acting injectable antipsychotic was additionally associated with later TRS (~15 months later). Conclusion: Our findings do not support a clear separation between early and late TRS but rather a continuum of the length of treatment before TRS onset. Having mild to very severe problems with positive symptoms at treatment start predicts earlier onset of TRS.
Population Growth Performance of Arma custos (Faricius) (Hemiptera: Pentatomidae) at Different Temperatures

Abstract Arma custos (Fabricius) (Hemiptera: Pentatomidae) is a natural predator that can control various agricultural and forestry pests. This study aimed to clarify the effects of temperature on the growth, reproduction, and population of the predator and to simulate its population growth. Using the age–stage, two-sex life table method, 18°C, 22°C, 26°C, 30°C, and 34°C were selected as the temperature conditions. A. custos can complete its life cycle at 18°C–30°C, and the developmental duration of each A. custos stage, adult pre-oviposition period, total pre-oviposition period, and the mean generation time (T) were shortened with the increase in temperature. The pre-adult mortality was significantly reduced at 26°C and 30°C. In addition, the fecundity of a single female and the gross reproductive rate were the highest at 30°C. Significant differences were observed in the intrinsic rate of increase (r) and the finite rate of increase (λ) under different temperature conditions, and both reached the maximum at 30°C. Results showed that adult A. custos raised at 26°C had a longer lifespan and the fecundity was higher at 30°C in comparison with the other temperatures. This study is the first to report the life cycle of A. custos at different temperatures, and the results can provide a scientific theoretical basis for the indoor artificial reproduction, outdoor release, and colonization of A. custos.
Mechanical properties of MoS2/graphene heterostructures

We perform classic molecular dynamics simulations to comparatively investigate the mechanical properties of single-layer MoS2 and a graphene/MoS2/graphene heterostructure under uniaxial tension. We show that the lattice mismatch between MoS2 and graphene will lead to an spontaneous strain energy in the interface. The Young's modulus of the heterostructure is much larger than that of MoS2. While the stiffness is enhanced, the yield strain of the heterostructure is considerably smaller than the MoS2 due to lateral buckling of the outer graphene layers owning to the applied mechanical tension.
Exploring the barriers to the antiretroviral therapy adherence among people living with HIV in Bangladesh: A qualitative approach

Introduction Since the evolution of highly active antiretroviral therapy (ART), a near-perfect ART adherence level (>95%) is needed to control viral suppression. Non-adherence to treatment may lead to acquired immunodeficiency syndrome (AIDS) and drug resistance. Though the Bangladesh government provides free treatment and counselling services to people living with human immunodeficiency virus (PLHIV), only 22% of the identified PLHIV continue treatment. Therefore, this study aims to explore the barriers that obstruct the Bangladeshi PLHIV to ensure ART adherence. Methods We conducted a qualitative study in Dhaka, Bangladesh, and recruited the sensitive study population following non-probability, mainly purposive sampling from a community-based registered organization for PLHIV. We conducted the in-depth interview using a semi-structured guideline with 15 consented respondents. We transcribed the audio-recorded interviews in the local language (Bangla) and then translated those into English for data analysis. During the data extraction process, the lead and corresponding authors independently extracted raw data to generate different themes and sub-themes and invited other authors to contribute when they could not solve any discrepancies. Results The study identified three significant categories of barriers at the individual, community, and institutional levels that negatively interfered with ART adherence. The most dominant barriers were discrimination and rejection related to stigma, as almost all participants mentioned these barriers. Stigmatizing attitudes and the discriminatory act of the community people and healthcare providers critically affected their treatment adherence. Other leading barriers were improper inventory management of ART-related medicines and CD4 tests and lack of proper counselling. In addition, we found that a positive approach toward life and family support motivated some respondents to overcome the barriers. Conclusions We recommended strengthening Bangladesh’s HIV/AIDS prevention, treatment, and management program with a special focus on the improvement of the supply chain of ART-related medicines and CD4 tests and ensuring proper counselling. In addition, we recommended strengthening the behaviour change communication and IEC activities at a large scale to destigmatize health facilities and community levels.
ON THE ABSENCE OF PHOTOSPHERIC NET CURRENTS IN VECTOR MAGNETOGRAMS OF SUNSPOTS OBTAINED FROM HINODE (SOLAR OPTICAL TELESCOPE/SPECTRO-POLARIMETER)

Various theoretical and observational results have been reported regarding the presence/absence of net electric currents in the sunspots. The limited spatial resolution of the earlier observations perhaps obscured the conclusions. We have analyzed 12 sunspots observed from Hinode (Solar Optical Telescope/Spectro-polarimeter) to clarify the issue. The azimuthal and radial components of magnetic fields and currents have been derived. The azimuthal component of the magnetic field of sunspots is found to vary in sign with azimuth. The radial component of the field also varies in magnitude with azimuth. While the latter pattern is a confirmation of the interlocking combed structure of penumbral filaments, the former pattern shows that the penumbra is made up of a “curly interlocking combed” magnetic field. The azimuthally averaged azimuthal component is seen to decline much faster than 1/ϖ in the penumbra, after an initial increase in the umbra, for all the spots studied. This confirms the confinement of magnetic fields and absence of a net current for sunspots as postulated by Parker. The existence of a global twist for a sunspot even in the absence of a net current is consistent with a fibril-bundle structure of the sunspot magnetic fields.
Motor Resonance During Action Observation and Its Relevance to Virtual Clinical Consultations: Observational Study Using Transcranial Magnetic Stimulation

Background Virtual clinical interactions have increased tremendously since the onset of the COVID-19 pandemic. While they certainly have their advantages, there also exist potential limitations, for example, in establishing a therapeutic alliance, discussing complex clinical scenarios, etc. This may be due to possible disruptions in the accurate activation of the human mirror neuron system (MNS), a posited physiological template for effective social communication. Objective This study aimed to compare motor resonance, a putative marker of MNS activity, estimated using transcranial magnetic stimulation (TMS) elicited while viewing virtual (video-based) and actual or real (enacted by a person) actions in healthy individuals. We hypothesized that motor resonance will be greater during real compared to virtual action observation. Methods We compared motor resonance or motor-evoked potential (MEP) facilitation during the observation of virtual (presented via videos) and real (enacted in person) actions, relative to static image observation in healthy individuals using TMS. The MEP recordings were obtained by 2 single-pulse (neuronal membrane excitability–driven) TMS paradigms of different intensities and 2 paired-pulse (cortical gamma-aminobutyric acid-interneuron–driven) TMS paradigms. Results This study comprised 64 participants. Using the repeated measures ANOVA, we observed a significant time effect for MEP facilitation from static to virtual and real observation states when recorded using 3 of the 4 TMS paradigms. Post hoc pairwise comparisons with Benjamini-Hochberg false discovery rate correction revealed significant MEP facilitation in both virtual and real observation states relative to static image observation; however, we also observed a significant time effect between the 2 action observation states (real > virtual) with 2 of the 4 TMS paradigms. Conclusions Our results indicate that visual cues expressed via both virtual (video) or real (in person) modes elicit physiological responses within the putative MNS, but this effect is more pronounced for actions presented in person. This has relevance to the appropriate implementation of digital health solutions, especially those pertaining to mental health.
Lifting Hospital Electronic Health Record Data Treasures: Challenges and Opportunities

Electronic health records (EHRs) have been successfully used in data science and machine learning projects. However, most of these data are collected for clinical use rather than for retrospective analysis. This means that researchers typically face many different issues when attempting to access and prepare the data for secondary use. We aimed to investigate how raw EHRs can be accessed and prepared in retrospective data science projects in a disciplined, effective, and efficient way. We report our experience and findings from a large-scale data science project analyzing routinely acquired retrospective data from the Kepler University Hospital in Linz, Austria. The project involved data collection from more than 150,000 patients over a period of 10 years. It included diverse data modalities, such as static demographic data, irregularly acquired laboratory test results, regularly sampled vital signs, and high-frequency physiological waveform signals. Raw medical data can be corrupted in many unexpected ways that demand thorough manual inspection and highly individualized data cleaning solutions. We present a general data preparation workflow, which was shaped in the course of our project and consists of the following 7 steps: obtain a rough overview of the available EHR data, define clinically meaningful labels for supervised learning, extract relevant data from the hospital’s data warehouses, match data extracted from different sources, deidentify them, detect errors and inconsistencies therein through a careful exploratory analysis, and implement a suitable data processing pipeline in actual code. Only few of the data preparation issues encountered in our project were addressed by generic medical data preprocessing tools that have been proposed recently. Instead, highly individualized solutions for the specific data used in one’s own research seem inevitable. We believe that the proposed workflow can serve as a guidance for practitioners, helping them to identify and address potential problems early and avoid some common pitfalls.
Waste tire pyrolysis and desulfurization of tire pyrolytic oil (TPO) – A review

ABSTRACT The presence of waste tires on open fields or households creates an ideal breeding ground for disease-carrying vermin, threatening human well-being. There are various technologies studied for efficient use of waste tires, such as pyrolysis, which results in char, oil, and non-condensable gases. Tire pyrolytic oil (TPO) has been reported to be similar to commercial diesel fuel. The current hurdle for using TPO in commercial diesel engines is the available sulfur content (>1.0 wt%). The disadvantages of sulfur in liquid fuels are its ability to reduce the engine’s life due to corrosion and the undesirable emission of SOx that subsequently damages public health and property. There is a rising need to develop efficient technologies for the desulfurization of such liquid fuels. Besides conventional hydrodesulfurization, other emerging technologies include adsorption, oxidation, photocatalytic degradation, and biological desulfurization. This paper reviews the status of pyrolysis of waste tires and desulfurization technologies for TPO. Implications: The nature of tires makes them extremely challenging to recycle due to the available chemically cross-linked polymer and, therefore, they are neither fusible nor soluble and, consequently, cannot be remolded into other shapes without serious degradation. The presence of tire waste on open fields or households creates an ideal breeding ground for disease-carrying vermin which pose a threat to humans. Also, disposal in landfills can lead to groundwater pollution by heavy metals and cause hazardous and uncontrolled fires. Owing to the growing environmental concerns, the exploration of economically viable and environmentally friendly techniques for the management of waste tires has been intensified in the recent past. Thermochemical routes such as combustion, gasification, and pyrolysis are important in the management of waste tires, reducing the environmental impacts of tire volarization, and allowing for the recovery of products. Given the depletion of fossil fuels and to meet the ever-growing demand for fuel energy, several initiatives to find alternative fuel sources are currently being taken. Fuel oil obtained from the pyrolysis of waste tires is becoming a promising alternative source of energy given its availability and higher heating value. Pyrolysis, an eco-friendly process, is the heating of matter in the absence of oxygen and is normally practiced for the thermochemical decomposition of different types of feedstock including biomass, coal, tires, and municipal solid waste. This paper reviews the current studies for pyrolysis of waste tires and multiple desulfurization technologies used for treating TPO globally. The detailed specification on operating conditions for the pyrolysis reactor in achieving desirable products in terms of composition and ratios are discussed.