Oncology Section* CSM 2017 Platform and Poster Presentations

Oncology Section* CSM 2017 Platform and Poster Presentations PLATFORM PRESENTATIONS Friday TIME: 11:00-1:00 PM and 3:00-5:00 PM (see the program for room assignments and specific times) PRIMARY MALIGNANT CARDIAC TUMORS: A LITERATURE REVIEW OF ANGIOSARCOMAS. Doherty DJ, Arena S, Claucherty E, Moore S. PURPOSE/HYPOTHESIS: The purpose of this study was to describe characteristics, risk factors, and physical activity levels of individuals diagnosed with cardiac angiosarcoma, a primary malignant tumor originating from cardiac endothelial cells, as identified by a literature review to describe trends and/or correlations. NUMBER OF SUBJECTS: Seventy published manuscripts met inclusion criteria: 46 case studies, 10 case series, and 14 literature reviews. Sixty-six individuals from the case studies and series were identified as having a primary malignant angiosarcoma of the heart. MATERIALS/METHODS: An electronic literature search using CINAHL, PubMed, EMBASE, and Cochrane databases and the terms “primary cardiac tumors” and “primary cardiac neoplasms” produced 897 citations. After duplicate and non-English language articles were excluded, 636 manuscripts remained, with a total of 70 fully extracted studies meeting additional inclusion criteria. A modified Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) template was developed and implemented for the purpose of evaluating features of each document by a minimum of 2 investigators. *The Research Committee of the Oncology Section has completed the peer-review process and has selected 16 platform presentations and 21 poster presentations focusing on key issues in oncology physical therapy. Posters will be on display during Exhibit Hall hours; refer to the CSM link at the on-site program to determine when authors will be available for discussion of their work. An alphabetical list (by title) of platform presentations and poster sessions follows. Full abstracts will be available at the APTA CSM link at http://apta.org, on the Oncology Sections’ Web site at http://www.oncologypt. org/, and on the Journal’s Web site at http:// journals.lww. com/rehaboncology. Rehabilitation Oncology Copyright C © 2016 Oncology Section, APTA. DOI: 10.1097/01.REO. 0000000000000041 RESULTS: Sixty-six individuals meeting the diagnostic criteria for primary malignant angiosarcoma of the heart were identified from the selected case studies. Characteristics included a male to female ratio of (1.25:1), with diagnosis most prevalent during the fourth decade of life among both genders. The most commonly presenting symptoms included dyspnea, chest pain/discomfort, breathlessness/shortness of breath, and pericardial effusion. Ethnic background, medical history, social history, physical activity level, and physical therapy intervention were omitted from all case histories. Surgery was the most common intervention following diagnosis (n = 38), followed by chemotherapy (n = 23) and radiotherapy (n = 14). The median survivorship after diagnosis was 7.1 months (range, 1-21 months; mode = 2 months). Thirteen subjects were documented as still surviving at the time of reporting (range, 4-29 months). Metastatic findings were most commonly reported in the lung, liver, and pericardium of the heart. CONCLUSIONS: A review of case studies and series describing individuals with a diagnosis of primary cardiac angiosarcoma revealed paucity of evidence in regard to possible risk factors, relevance or impact of physical therapy during the various stages of diagnosis or intervention, or a correlation between physical activity or other lifestyle risk factors and tumor proliferation. CLINICAL RELEVANCE: Lack of evidence regarding preemptive risk reduction, inclusive of prior physical activity levels, limits a health care provider’s ability to provide care aimed toward thwarting malignant cell conversion. Further research of individuals diagnosed with cardiac angiosarcoma with intention toward capturing these data is warranted to improve prevention and early detection efforts.