Miracle-dz/UniFAR-FTUs huggingface dataset:
Investigation of association between the human neuropeptide Y gene Leucine7Proline polymorphism and obesity in a population from Turkey

of between the human neuropeptide y gene leucine7proline polymorphism Obesity, an important public health issue, is a risk factor for many diseases and has been associated with many genes. The aim of this study was to investigate if there is an association between an NPY gene polymorphism, Leu7Pro, and obesity and/or obesity-related phenotypes. A total of 84 obese cases (45 female and 39 male) and a total of 77 non-obese control subjects (38 female and 39 male) were included in this case-control study. Body weight and height measurements were used for calculation of Body Mass Index (BMI) and the ones in the ranges of 18 to 25 kg/m 2 were considered normal and the ones 30 kg/m 2 and over were considered obese from the subjects. Minor allele frequency for Leu7Pro polymorphism was 3.5% it was found to be confirm these findings and can contribute and shed light on the genetic factors playing a part in Turkey population.
Reversible Networks for Memory-efficient Image-to-Image Translation in 3 D Medical Imaging

The Pix2pix [24] and CycleGAN [52] losses have vastly improved the qualitative and quantitative visual quality of results in image-to-image translation tasks. We extend this framework by exploring approximately invertible architectures which are well suited to these losses. These architectures are approximately invertible by design and thus partially satisfy cycle-consistency before training even begins. Furthermore, since invertible architectures have constant memory complexity in depth, these models can be built arbitrarily deep. We are able to demonstrate superior quantitative output on the Cityscapes and Maps datasets. Additionally, we show that the model allows us to perform several memory-intensive medical imaging tasks, including a super-resolution problem on 3D MRI brain volumes. We also demonstrate that our model can perform a 3D domain-adaptation and 3D super-resolution task on chest CT volumes. By doing this, we provide a proof-of-principle for using reversible networks to create a model capable of pre-processing 3D CT scans to high resolution with a standardized appearance.
Tergal and Sternal Glands in Ants

Chemical signals, or pheromones as they are generally called, play a central role in the complex communication system of ant societies. During the last 20 years a number of exocrine glands have been identified as the anatomical sources for a diversity of pheromones which mediate sexual and social behavior in ants (for reviews see Wilson 1971, Blum 1977, H611dobler 1978). In recent years, however, several hitherto unknown exocrine glandular structures have been discovered in ants and the behavioral functions of some of them have already been determined. In this paper we will review these findings and will report the new results of our comparative morphological study of tergal and sternal glands in ants.
A Chemical Signature from Fast-rotating Low-metallicity Massive Stars: ROA 276 in ω Centauri

We present a chemical abundance analysis of a metal-poor star, ROA 276, in the stellar system ω Centauri. We confirm that this star has an unusually high [Sr/Ba] abundance ratio. Additionally, ROA 276 exhibits remarkably high abundance ratios, [X/Fe], for all elements from Cu to Mo along with normal abundance ratios for the elements from Ba to Pb. The chemical abundance pattern of ROA 276, relative to a primordial ω Cen star ROA 46, is best fit by a fast-rotating low-metallicity massive stellar model of 20 , [Fe/H] = −1.8, and an initial rotation 0.4 times the critical value; no other nucleosynthetic source can match the neutron-capture element distribution. ROA 276 arguably offers the most definitive proof to date that fast-rotating massive stars contributed to the production of heavy elements in the early universe.
IMPROVING SPATIAL ABILITY SKILLS OF FIRST-YEAR STUDENTS IN BASIC ENGINEERING DRAWING USING A SOLID PAIR MODEL

Good spatial ability skills are an important component of an engineer’s ability to create and interpret engineering drawings, which is demanding in thinking, being a problem-solving process. The ability of an engineer to visualize in 3D is a cognitive skill that is attached to success in basic engineering drawing subjects. Engineering and technology education students need good spatial ability skills to understand several topics in basic engineering drawings like orthographic projection, axonometric drawing, sectional view, and hidden details drawings. This study aims at improving spatial ability skills using a solid pair model among first-year technical education students of Kaduna State College of Education Gidan Waya. A Quasi-experimental research design was used for the study, a standards pre and post-test were used to conduct a visualization transformation assessment to measure the students’ level of spatial ability skills. The study shows that after treatment using a solid pair model, the student without prior knowledge in basic engineering performed above average, likewise students with prior knowledge in the control and experimental group performed above average. The results indicate that a solid pair model was effective for improving spatial ability skills among first-year technical education students. This study implies to educators that there is need to appropriately enforce the use of a solid pair model for effective teaching and learning of basic engineering drawing. It is, therefore, affirmed that the use of a solid pair model in teaching basic engineering drawings should be enhanced with other teaching methods. Marwa, N. J. | Department of Technical Education Kaduna State College of Education, Gidan waya, Kafanchan, Kaduna State, Nigeria.
Structural and Thermochronologic Constraints on the Cenozoic Tectonic Development of the Northern Indo‐Burma Ranges

The ~1,500‐km‐long, north trending Eastern Flanking Belt of the Himalayan‐Tibetan orogenic system is located along the eastern margin of the Indian subcontinent. Although the belt is a key element of the Cenozoic India‐Asia collisional zone, its tectonic evolution remains poorly understood. This lack of knowledge has impacted our ability to differentiate between competing hypotheses for the evolution of the India‐Asia collision. To address this problem, we integrate constraints on the structural framework and magnitude of Cenozoic shortening strain with thermochronology of the northernmost segment of the belt located directly southeast of the eastern Himalayan syntaxis (i.e., the northern Indo‐Burma Ranges). The study area exposes a southwest directed thrust belt that is bounded by the Indian craton in the west and the right‐slip Jiali fault zone in the east. New and existing (U‐Th)/He and 40Ar/39Ar thermochronologic data indicate that thrust‐related cooling occurred from ~36 Ma in the northeast to ~5.6 Ma in the southwest. Episodes of out‐of‐sequence thrusting occurred at ~30–20, ~14–12, and ~11–6 Ma within the thrust belt. Restoration of the thrust belt yields a minimum horizontal shortening of ~280 km (~86%). These results combined with (1) the recorded local absence of several major Himalayan‐Tibetan lithologic units (i.e., Tethyan Himalayan Sequence, Greater Himalayan Sequence, and southern Gangdese batholith) and (2) the southward decrease in the thrust‐belt width (33–5 km) suggest a complex history of thrusting in the northern Indo‐Burma Ranges and an spatial increase in Cenozoic crustal shortening and/or continental underthrusting from west to east across the eastern Himalayan syntaxis.
Corruption in Brazilian Public Administration: A Study on the Perception of Law Enforcement Agents

Corruption is a complex phenomenon that confronts all types of organizations. It also takes place in the underground of the organizational life. However, due to the difficulty in obtaining data it is not as researched and studied as it should be in organizational studies. The goal of this paper is to analyze the corruption in Brazilian public administration based upon the perception of law enforcement agents. The paper is based on qualitative research which used primary and secondary data, however most part of the data was obtained in depth interviews with 12 Brazilian law enforcement agents. The results of the research point out seven main findings. The interviewees also highlighted that corruption can be seen in all areas of citizen's life, including in daily practices, so it is important to find new forms to combat Transparency, greater social participation, control and punishment were listed as the main elements to be explored in the fight against corruption. The main contribution of this article is to discuss the limitations of the rationality of law enforcement agents in relation to a complex phenomenon, as corruption in public administration, in a country with high corruption incidence, as Brazil.
Sierra Gorda 009: A new member of the metal‐rich G chondrites grouplet

We investigated the metal‐rich chondrite Sierra Gorda (SG) 009, a member of the new G chondrite grouplet (also including NWA 5492, GRO 95551). G chondrites contain 23% metal, very reduced silicates, and rare oxidized mineral phases (Mg‐chromite, FeO‐rich pyroxene). G chondrites are not related to CH‐CB chondrites, based on bulk O, C, and N isotopic compositions, mineralogy, and geochemistry. G chondrites have no fine‐grained matrix or matrix lumps enclosing hydrated material typical for CH‐CB chondrites. G chondrites’ average metal compositions are similar to H chondrites. Siderophile and lithophile geochemistry indicates sulfidization and fractionation of the SG 009 metal and silicates, unlike NWA 5492 and GRO 95551. The G chondrites have average O isotopic compositions Δ17O>0‰ ranging between bulk enstatite (E) and ordinary (O) chondrites. An Al‐rich chondrule from SG 009 has Δ17O>0‰ indicating some heterogeneity in oxygen isotopic composition of G chondrite components. SG 009’s bulk carbon and nitrogen isotopic compositions correspond to E and O chondrites. Neon isotopic composition reflects a mixture of cosmogenic and solar components, and cosmic ray exposure age of SG 009 is typical for O, E, and R chondrites. G chondrites are closely related to O, E, and R chondrites and may represent a unique metal‐rich parent asteroid containing primitive and fractionated material from the inner solar system. Oxidizing and reducing conditions during SG 009 formation may be connected with a chemical microenvironment and possibly could indicate that G chondrites may have formed by a planetesimal collision resulting in the lack of matrix.
Latent Estimation of Piracy Quality and its Effect on Revenues and Distribution: The Case of Motion Pictures

Conventional wisdom holds that illegal copies cannibalize legitimate sales, even though previous research has found mixed effects, with illegal copies acting as both a substitute and complement. Yet, a relatively unexamined aspect to date is the quality of illegal copies. Building on product uncertainty and production quality, we propose that higher quality copies can benefit sales when product uncertainty is high, such as during the launch period. Using motion picture and online piracy data, we estimate piracy quality using a latent item response theory (IRT) model based on keyword signals in the copies. An interdependent system jointly estimates movie screens, revenues, downloads, and available illegal copies with piracy quality in both the launch and post-launch periods. We find that at launch, when rather little is known about the movie, higher quality illegal copies demonstrate a positive effect on revenues (sampling). In the post-launch period, however, higher quality illegal copies exhibit a negative effect on revenues (substitution). The findings suggest producers can alleviate product uncertainty through higher quality samples at product launch while diluting piracy quality post-launch.
Testing the Efficacy of a Tier 2 Mathematics Intervention

The purpose of this closely aligned conceptual replication study was to investigate the efficacy of a Tier 2 kindergarten mathematics intervention. The replication study differed from the initial randomized controlled trial on three important elements: geographical region, timing of the intervention, and instructional context of the counterfactual. Similar to the original investigation, however, the current study tested the same intervention, used the same outcome measures and statistical analyses, and involved the same population of learners. A total of 319 kindergarten students with mathematics difficulties from 36 kindergarten classrooms participated in the study. Students who were randomly assigned to the treatment condition received the intervention in small-group formats, with 2 or 5 students per group. Control students participated in a no-treatment control condition. Significant effects on proximal and distal measures of mathematics achievement were found. Effect sizes obtained for all measures fell within or exceeded the upper bound of the effects reported in the initial study. Implications for systematically situating replication studies in larger frameworks of intervention research and reporting rates of treatment response across replication studies are discussed.
Adrenal function evaluation in critically ill dogs with low doses of synthetic ACTH

The hypothalamus-pituitary-adrenal axis function may be impaired in patients with critical illnesses, especially cases of sepsis, named critical illness-related corticosteroid insufficiency (CIRCI). This study examined the function of the hypothalamic-pituitary-adrenal axis in normal dogs (n = 10) and dogs with critical diseases (n = 16), through determinations of endogenous ACTH (adrenocorticotropic hormone), basal cortisol and cortisol after stimulation in low doses of synthetic ACTH (1.0μg/kg/IV). The stimulation test with ACTH dose tested was verified as effective for evaluation of adrenal function in healthy and sick dogs. Ill dogs differed from healthy dogs by presenting higher basal cortisol values. Eight sick dogs presented a decrease in endogenous ACTH, basal cortisol, or Δ-cortisol. No significant differences were found between the control groups and critically ill dogs for the values of endogenous ACTH, cortisol after stimulation or Δ-cortisol. We concluded that the stimulation test with low-dose ACTH was effective for evaluation of adrenal function, as well as the fact that a considerable portion of critically ill dogs studied here, especially with sepsis, had evidence of inadequate corticosteroid response to stress.
64 Slice CT Evaluation of Anatomical Variations of Main Arteries Arising from the Abdominal Aorta and their Branching Pattern

Aim: To determine the comprehensive spectrum of celiac axis including SMA, IMA, hepatic and renal artery variations with the use of multi-detector computed tomography (MDCT). Material and Methods: This retrospective and prospective study was conducted in the Department of Radio diagnosis, Dr. S.N. Medical College and Associated Group of Hospitals, Jodhpur in 500 patients subjected to MDCT abdomen for various indications. Patients with a history of prior major upper abdominal surgery and patients with occlusion of celiac, hepatic, SMA and renal arteries were excluded. Results: Seven types of celiac axis anatomic variations were identified in our study (including SMA). Anatomic variations in celiac axis were seen in 9% of patients with ambiguous celiac axis anatomy in 2% of the patients. IMA origin was normal in all patients. CHA originated from celiac axis in 95.20% of the patients. Variations in anatomic origin of CHA were seen in 2.8% patients. Normal origin of RHA from HAP and CHA was seen in 77.75% patients. LHA originated from HAP and CHA in 77.75% patients. MHA originated from RHA in 48% patients, LHA in 12% and from CHA in 12% cases. Origin of MHA could not be defined in 28% of patients. GDA originated from CHA in 95% of patients. Single renal artery was seen in 53% patients. 49% patient have variation in the form of early branching and additional renal arteries. Conclusion: Variations in the celiac trunk, SMA, hepatic artery and renal artery are common, and their detection is important prior to any interventions or abdominal surgeries.
From Rain Removal to Rain Generation

Single image deraining is an important yet challenging issue due to the complex and diverse rain structures in real scenes. Currently, the state-of-the-art performance on this task is achieved by deep learning (DL)-based methods that mainly benefit from abundant pre-collected paired rainy-clean samples either manually synthesized or semi-automatically generated under human supervision. This tends to bring a large labor for data collection and more importantly, such manner neglects to elaborately explore the intrinsic generative mechanism of rain streaks which should be related to the most insightful understanding of the task. Against this issue, we investigate the generative process of rainy image and construct a full Bayesian generative model for generating rains from automatically extracted latent variables that represent physical structural factors for depicting rains, like direction, scale, and thickness. To solve this model, we propose an algorithm where the posteriors of latent variables are parameterized as CNNs and all the involved parameters can be inferred under a concise variational inference framework in a data-driven manner. Especially, the rain layer is modeled as an implicit distribution, parameterized as a generator, which avoids subjective prior assumptions on rains as in traditional model-based methods. More practically, from the learned generator, rain patches can be automatically generated and utilized to simulate diverse training pairs so as to enrich and augment the existing benchmark datasets. Comprehensive experiments substantiate that the proposed model has fine capability of generating plausible samples that not only helps significantly improve the deraining performance of current DL-based single image derainers, but also largely loosens the requirement of large training sample pre-collection for the task.
The structure of random partitions of large integers

Random partitions of integers are treated in the case where all partitions of an integer are assumed to have the same probability. The focus is on limit theorems as the number being partitioned approaches ∞. The limiting probability distribution of the appropriately normalized number of parts of some small size is exponential. The large parts are described by a particular Markov chain. A central limit theorem and a law of large numbers holds for the numbers of intermediate parts of certain sizes. The major tool is a simple construction of random partitions that treats the number being partitioned as a random variable. The same technique is useful when some restriction is placed on partitions, such as the requirement that all parts must be distinct
Kinematics of the Tucana Dwarf Galaxy: an unusually dense dwarf in the Local Group

We present new FLAMES+GIRAFFE spectroscopy of 36 member stars in the isolated Local Group dwarf spheroidal galaxy Tucana. We measure a systemic velocity for the system of vTuc=216.7+2.9−2.8vTuc=216.7−2.8+2.9 km s−1, and a velocity dispersion of σv,Tuc=14.4+2.8−2.3σv,Tuc=14.4−2.3+2.8 km s−1. We also detect a rotation gradient of dvrdχ=7.6+4.2−4.3dvrdχ=7.6−4.3+4.2 km s−1 kpc−1, which reduces the systemic velocity to vTuc=215.2+2.8−2.7vTuc=215.2−2.7+2.8 km s−1 and the velocity dispersion to σv,Tuc=13.3+2.7−2.3σv,Tuc=13.3−2.3+2.7 km s−1. We perform Jeans modelling of the density profile of Tucana, using the line-of-sight velocities of the member stars. We find that it favours a high central density consistent with ‘pristine’ subhaloes in Λ cold dark matter, and a massive dark matter halo (∼1010 M⊙) consistent with expectations from abundance matching. Tucana appears to be significantly more centrally dense than other isolated Local Group dwarfs, making it an ideal laboratory for testing dark matter models.
Clinical Data Combined With Modeling and Simulation Indicate Unchanged Drug‐Drug Interaction Magnitudes in the Elderly

Age‐related comorbidities and consequently polypharmacy are highly prevalent in the elderly, resulting in an increased risk for drug‐drug interactions (DDIs). The effect of aging on DDI magnitudes is mostly uncertain, leading to missing guidance regarding the clinical DDI management in the elderly. Clinical data obtained in aging people living with HIV ≥ 55 years, who participated in the Swiss HIV Cohort Study, demonstrated unchanged DDI magnitudes with advanced aging for four studied DDI scenarios. These data plus published data for midazolam in the presence of clarithromycin and rifampicin in elderly individuals assessed the predictive potential of the used physiologically‐based pharmacokinetic (PBPK) model to simulate DDIs in the elderly. All clinically observed data were generally predicted within the 95% confidence interval of the PBPK simulations. The verified model predicted subsequently the magnitude of 50 DDIs across adulthood (20–99 years) with 42 scenarios being only verified in adults aged 20–50 years in the absence of clinically observed data in the elderly. DDI magnitudes were not impacted by aging regardless of the involved drugs, DDI mechanism, mediators of DDIs, or the sex of the investigated individuals. The prediction of unchanged DDI magnitudes with advanced aging were proofed by 17 published, independent DDIs that were investigated in young and elderly subjects. In conclusion, this study demonstrated by combining clinically observed data with modeling and simulation that aging does not impact DDI magnitudes and thus, clinical management of DDIs can a priori be similar in aging men and women in the absence of severe comorbidities.
Genetic diversity and structure of Prunus padus populations in South Korea based on AFLP markers

Abstract We applied seven pairs of primer-restriction enzyme combinations to investigate the genetic diversity, genetic differentiation, and genetic structure of Prunus padus populations with AFLP markers. The values obtained for average of effective alleles (A e), percentage of polymorphic loci (%P), Shannon’s diversity index (I), and expected heterozygosity (H e) were 1.38, 81.4, 0.357, and 0.223%, respectively. The expected heterozygosity (Hj) obtained by using a Bayesian method was 0.256. The level of genetic diversity obtained for P. padus was low compared to that of Prunus species and other species with a similar life history. The inbreeding coefficient (F IS) from the approximated Bayesian method was 0.767. This value was lower than that obtained for Ulmus davidiana, which undergoes both sexual and asexual reproduction. However, the value obtained was larger than that for other species that undergo sexual reproduction, such as, Carpinus laxiflora, Phellodendron amurense, and Acer pseudosieboldianum. The value of genetic differentiation was 0.245 from AMOVA (ΦST) and 0.278 from Bayesian method (θII). The obtained level of genetic differentiation was large compared to that of other Prunus species plants and other species with a similar life history. According to UPGMA and Bayesian clustering, 11 populations were divided into two genetic groups. However, some populations were detected as weak genetic structures according to the geographical distribution. It was occurred by forest succession, asexual propagation strategies to adapt local environmental change, and gene flow being gradually decreased due to population fragmentation by demographic disturbances.