Miracle-dz/UniFAR-FTUs huggingface dataset:
Prevalence and Socio-Demographic Characteristics Related to Stress, Anxiety, and Depression among Patients with Major Tha-lassemia in the Kermanshah County

Thalassemia is one of the most common chronic and genetic blood disorders in the world that can followed by several complications, such as mental disorders. The aim of this study was to determine the prevalence and socio-demographic characteristics associated with stress, anxiety and depression among patients with thalassemia major in Kermanshah during 2014. This cross-sectional study done among 64 patients with thalassemia major during 2014; in the participants were randomly selected among patients who referred to Mohammad Kermanshahi hospital in the Kermanshah County to take part in this study. A standard questionnaire (DASS-21) which analyzed stress, anxiety and depression was applied for collecting data and data were analyzed by SPSS version 20 using chi-square statistical tests. The mean age of respondents was 22.31 years [95% CI: 20.42, 24.21], ranged from 14 to 58 years. Findings showed the 60.9%, 59.4 % and 18.8 % of the respondents were suffering from extremely severe anxiety, depression, and stress, respectively. Furthermore, our findings showed marital status and job have significant relationship with anxiety (P<0.05); education level has significant relationship with depression (P<0.05). Our findings indicated high level of prevalence of mental disorder among patients with thalassemia major. These results can be warning to health policy makers in Iran; and should be the focus of special attention.
Performance of Different Mulberry/ Morus Sp/ Genotypes and their Effect on Mulberry Silkworm, Bombyx Mori (Lepidoptera: Bombycidae)

Mulberry /Morus sp / is the primary feed plant for Bombyx mori (Lepidoptera: Bombycidae). The studies were conducted in field and laboratory conditions with the objectives to evaluate the agronomic and their rearing performance of different genotypes of mulberry on silkworms. About 6 genotypes of mulberry namely, Nekemte, Jimma, M-4, K-2, S-13 and Local were evaluated in the field and laboratory. The treatments were arranged with RCBD in the field and CRD for laboratory experiments in three replications. Significant differences were observed in agronomic and rearing performances of genotypes of mulberry. In field, maximum leaf production per plant (371.3 and 373.1 kg/ha), fresh leaf weight (26,503 and 26,333 kg/ha) and dry leaf weight (8027 and 8268 kg/ha) were recorded from S-13 and K-2, respectively. However, minimum leaf weight (9435kg/ha) was recorded from local genotype. In addition, there were significant differences in rearing performances of silkworms fed on different genotypes of mulberry. Among different genotypes, silkworms fed on leaf of S-13 and K-2 gave better results such as cocoon weight (1.11g and 1.03g), pupal weight (0.924g and 0.864g), shell weight (0.187g and 0.168g), silk ratio (16.82% and 16.35%), as compared to other genotypes. In general, S-13 and K-2 showed better results in agronomic performances as well as in rearing performance of silkworms for improving silk production as compared to other genotypes.
Diode Laser De-Bonding of Pre-Coated Ceramic Brackets

Objective: The purpose of this In vitro study was to investigate the effects of diode laser de-bonding on the shear bond strength and adhesive remnant index of pre-coated ceramic brackets bonded to extracted human premolars. Materials and Methods: Eighty freshly extracted upper premolars were used. The teeth were divided into two groups according to the pre-coated ceramic brackets applied (APC II and APC plus). Each group was subdivided into two subgroups according to the method of de-bonding, either by laser diode (study groups) or without laser application (control groups) (N=20). The shear bond test was performed after the laser pulse had been applied, and the adhesive remnant index (ARI) scores were assigned to each specimen. Random samples from each group were selected for SEM observation. Statistical analysis was performed via a one-way ANOVA analysis and Chi-square test. Results: Significantly (p ˂ 0.001) lower shear bond strengths were found in the laser groups compared with the control groups. Similarly, the adhesive remnant index scores were significantly different (p ˂ 0.001); the laser group had nearly twice as much adhesive, with ARI scores of 2 or 3. Conclusion: The application of the diode laser is effective in de-bonding pre-coated ceramic brackets. [Mohammad Almohaimeed and Sahar Abd El Halim. Diode Laser De-Bonding of Pre-Coated Ceramic Brackets. J Am Sci 2013;9(5s):177-181]. (ISSN: 1545-1003). http://www.jofamericanscience. org. 28
Formulation and in-vitro characterization of floating mucoadhesivebeads of Levofloxacin Hemihydrate

The main aim of this investigation was to develop gastroretentive beads for controlled release of the drug for the treatment of H.pylori infections more efficiently by releasing the drug especially in stomach for a prolonged duration of time. Floating mucoadhesive beads were prepared to prolong the gastric retention of the drug. Floating mucoadhesive alginate - hydroxypropyl methylcellulose beads of Levofloxacin hemihydrate were prepared by using emulsion gelation method. The interactions between drug and polymers were investigated by Fourier transform infrared (FTIR) Spectroscopy and Differential scanning calorimetry (DSC). Prepared beads were evaluated for particle size, entrapment efficiency, and surface morphology by using scanning electron microscopy. In vitro drug release studies were carried out. According to FTIR and DSC, the drug did not show any evidence of an interaction with the polymers used. From the in vitro drug release studies, the drug release from formulation F6 was found to be 71.68 % and showed controlled release. From the results it can concluded that F6 formulation was found to be better than the other formulations, as it showed controlled drug release. Hence it may achieve the aim of controlling the drug release, prolong retention time in GIT and reduce the frequency of dosing.
Heavy Metals Removal by Nickel-Oxide Nanoparticles Synthesised by Lemon Juice Extract

Applicability of nickel-oxide nanoparticles for the selective removal of heavy metals from synthetic metal solutions was investigated. An average size of 26 nm were synthesized using lemon juice extract as fuel by solution combustion method and characterized by X-Ray diffraction, SEM and FTIR. Batch experiments were conducted to determine adsorption kinetics and mechanisms of Cr (VI), Cu (II) and Ni (II). The adsorption process was found to be highly pH dependent. Data were well defined with Langmuir isotherms. Adsorption mechanisms were found to follow pseudo second order for Cr (VI), Cu (II) and Ni (II). Keywords--Nickel-oxide nanoparticles, solution combustion method, heavy metal removal, adsorption kinetics, adsorption isotherms
Crop Physiological Maturity: A Proper Stage to Harvest Soybean Crop

Soybean (Glycine max (L.) Merrill) being legume crop, fixes atmospheric nitrogen and improves the soil fertility. It is a unique crop of versatile nutritional attribute, yielding both oil and protein. It is truly a “Wonder crop” as its vast multiplicity uses as food, fodder, industrial products and residues in soil and also accounting for nearly 50 per cent of total oilseed acreage as well as production.
Volumetric Overload Shocks (VOS) Causing the Acute Respiratory Distress Syndrome (ARDS): The Complete Evidence

Introduction and Objective: To report evidence that VOS causes ARDS. Material and Methods: Literature analysis revealed overlooked facts and errors on fluid therapy. My research included: 1. A prospective clinical study on 100 TURP patients among whom 10 developed TURP syndrome. 2. A case series of 23 patients who suffered TURP syndrome. 3. A physics study on the hydrodynamics of the G tube. 4. A physiological study on the hind limp of sheep. Results: The literature analysis revealed many overlooked facts and errors on fluid therapy and its correction is given: 1. The prospective study demonstrates VOS is the most important factor causing TURP syndrome and ARDS. 2. The case series study affirmed VOS is the patho-etiology of TURP syndrome and ARDS. The correct therapy is HST that saved the lives of 20 patients. 3. The physics study on the G tube showed that the proximal pressure akin to arterial pressure causes suction, not filtration, and provided the phenomenon of the G tube as the correct replacement for Starling’s law. 4. The physiological study on the hind limp of sheep demonstrated that arterial pressure induced suction not filtration and the capillary works as G tube not Poiseuille's tube. Conclusion: Overlooked facts and errors on fluid therapy mislead physicians into giving too much fluids inducing VOS and causing ARDS. It is clear that VOS causes ARDS. Both physics and physiological evidence prove Starling’s law is wrong. The phenomenon of the G tube provides the correct replacement.
Kaempferol Effects on Human Gingival Fibroblasts

Objective: Kaempferol is a natural flavonol found in many dietary fruits, vegetables, and medicinal herbs. It reportedly has multiple beneficial properties as analyzed in vivo and in vitro. The objective of this study was to determine cytoprotective, anti-inflammatory, and wound healing characteristics of kaempferol in cultured human gingival fibroblasts. Materials & Methods: To determine cytotoxicity and doseresponse, commercially available human gingival fibroblasts were cultured in 0, 5, 10, 25, 50, 100, 250 or 500 μM kaempferol for 24 hours prior to a colorimetric MTT assay. To determine anti-inflammatory effects, gingival fibroblasts were pre-treated with one of several concentrations of kaempferol and challenged with 10 ng/ml tumor necrosis factor alpha (TNFα). Culture supernatants were assayed for levels of secreted interleukin-8 by ELISA. Kaempferol effects on the cell migration phase of wound healing in confluent nicotine-treated fibroblasts were determined using an in vitro scratch assay. Results: By MTT assay kaempferol at 5, 10, 25, and 50 μM was not detrimental to gingival fibroblast survival, in contrast 100, 250, and 500 μM kaempferol proved to be highly cytotoxic to gingival fibroblasts. Kaempferol at 5, 10, 25, and 50 μM significantly suppressed TNFαinduced IL8 secretion. Of concentrations assayed, 5 μM kaempferol significantly stimulated the migration of gingival fibroblasts from a scratch wound edge 24 hours post-wound. In nicotine-treated gingival fibroblasts, 5 μM kaempferol significantly increased the migration of gingival fibroblasts from the wound edge. The cells migrating from the wound edge retained the characteristic elongated spindle morphology. Conclusion: In cultured human gingival fibroblasts, kaempferol demonstrates cytoprotective, anti-inflammatory, and pro-migratory properties in a concentration-dependent manner. These properties of kaempferol have implications for oral cavity mucosal wound healing.
Requirements Prioritization Using Analytic Network Process (ANP)

— Software project development deals with many requirements. Since software is developed in different increments, it is difficult for requirement engineers to implement all these requirements in one single increment. For this purpose, prioritization of requirements is essential in order to deliver right product on right time. A thorough survey of literature depicts that no requirements prioritizing methodology prioritizes dependent requirements. Moreover, performance of existing methodologies regarding requirements prioritization needs improvement. During the literature survey, most of the prioritization methodologies were studied and critically reviewed. After analyzing different techniques, a new requirements prioritization methodology is proposed and a model is developed that can prioritize both dependent and independent requirements. The interdependent requirements will be prioritized with newly proposed requirements prioritization technique that is Analytic Network Process (ANP). The simulation results of the proposed technique showed that ANP produced finest outcomes for prioritizing requirements. The simulations were carried out in MATLAB software.
A Very Rare Case of Intra-cardiac Lymphoma Presenting as Splenic and Renal Infarcts

Primary lymphomas of the heart are extremely rare, accounting for less than 2% of all primary cardiac tumors. Histologic confirmation is fundamental in developing an early treatment plan, facilitating improved prognosis. Clinical presentation is heterogeneous and generally related to the affected cardiac chamber. The right atrium and right ventricle are the two most frequently involved sites [1]. Arterial and/or venous embolic events also may occur depending on the site of cardiac involvement and should prompt further investigation to confirm the diagnosis. Our patient presented with vague symptoms of abdominal pain. Evaluation revealed splenic and renal infarcts. Further investigations revealed a 4.5 x 3.5 cm left ventricular mass; multiple biopsies failed to yield a diagnosis. Intraoperative resection allowed for histologic confirmation of primary cardiac diffuse large B-cell lymphoma. Unfortunately, 2 weeks after resection her tumor had recurred. Chemotherapy with R-EPOCH resulted in complete remission after 2 cycles and remained in remission after total of 6 cycles. This case demonstrates successful treatment of an aggressive non-germinal center rare intracardiac lymphoma with a more aggressive regimen R-EPOCH compared to R-CHOP. Shah S1*, Daboul N2, Lee D2 and Mewawalla P2 1Division of Internal Medicine, Allegheny Health Network, USA 2Division of Hematology and Stem Cell Transplant, Allegheny Health Network Cancer Institute, USA
ASSESSMENT OF WATER BORNE DISEASES BURDEN AND POTENTIALLY BIOHAZARDOUS AGENTS IN DRINKING WATER OF DISTRICT SHAHEED BENAZEERABAD

Biohazardagents figure in drinking water concernfor different waterborne-illnesses (viral, bacterial and protozoan infections) internationally reported, poor quality (physical, chemical and biological contamination) of drinking waterincreasing water pollution not only deteriorates water quality, but also contributes to public health problems, economic stress and social disprosperity. Potential biohazards Agents can cause sporadic waterborne disease or outbreaks, Different Physico-chemical parameters ( pH, Electric conductance (EC) , Salinity , TDS (Total Dissolved Salts) , Cl, Co, Ni, Zn, Mn, Fe, Cd and As), Bacteriological contamination according to PSQCA (Pakistan Standard Quality Control Authority)/WHO models were examined. The outcomes suggests that biohazards may be resulted in outbreak of water borne diseases and it was observed that quality of drinking water of the study area is unsafe for human consumption.
Regional Brain Amino Acids Imbalances in Reserpine Rat Model of Depression: An Antidepressive Effect of Pomegranate Juice

Depression is an extremely common pathological complex with psychological, neuroendocrine, and pathological symptoms. The present evaluated the antidepressant effect of pomegranate juice by using the in experimental rat model of reserpinized rat. The occurrence of depression was determined using forced swimming test (FST). Fluoxetine was used as the reference antidepressant drug. In addition the free amino acids (aspartic, glutamic, Glycine. Gamma amino butyric acid, GABA and taurine) content of both brain cortex and midbrain and brainstem were determined. Daily administration of reserpine at a dosage of 1mg/kg for 14 days increased the immobility time in FST without remarkable changes in motor function in the open field test (OFT), indicating the occurrence of depression. Both the individual treatment of fluoxetine and pomegranate juice and their combination significantly reduced the immobility time in FST, indicating their antidepressant activities. In addition, reserpine disturbed the normal levels of both excitatory (glutamic and asparatic) and inhibitory (glycine and GABA) and taurine in both brain cortex and midbrain and brain stem. Both the individual treatment of fluoxetine and pomegranate juice and their combination significantly restored the normal levels of brain free amino acids. The study suggested that reserpine induced depression by altering the normal balance of both brain excitatory and inhibitory amino acids neurotransmission, On the other hand, both the individual treatment of fluoxetine and pomegranate juice and their combination significantly rebalanced the normal brain transmission of excitatory and inhibitory amino acids. The observation that that the combined effect moderately exceeded the individual treatments which might indicate that both fluoxetine shared similar pathways to produced their antidepressive effects, which represent a type of competition. Hence, it is a good opportunity to reduced the fluoxetine dose and compensate by pomegranate as food supplement to attain the full antidepressive effect [Ahmed M. Shehata, Abdel Aziz A. Diab, Gehan A Elmenofi and Marwa, A. A Hassan. Regional Brain Amino Acids Imbalances in Reserpine Rat Model of Depression: An Antidepressive Effect of Pomegranate Juice. J Am Sci 2015;11(9):18-26]. (ISSN: 1545-1003). http://www.jofamericanscience. org. 3
EFFICACY OF ASCORBIC ACID AS PROTECTIVE SUBSTANCE ON SODIUM FLUORIDE INDUCED REPRODUCTIVE IMPAIRMENT

This study deals with the evaluation of ascorbic acid (Vit-C) as protective agent against Sodium fluoride (NaF) toxicity on male reproductive system. Present Observation clearly reveals the toxic effect of NaF on male reproductive system as body weight, testicular weight, epididymal weight, sperm count, sperm motility, SGPT, SGOT and serum testosterone have been hampered in significant manner. Besides this, improvement or recovery has taken place significantly on these parameters after co-administration or supplement of Vit-c along with NaF. This proves the protective efficacy of Vit-c.
SOIL AMENDMENT WITH OAK DEBRIS ENHANCES THE BIOLOGICAL ACTIVITY OF METARHIZIUM ANISOPLIAE, AGAINST MELOIDOGYNE JAVANICA

Biocontrol potential of Metarhizium anisopliae on some phytonematodes has been reported earlier. Considering the importance of organic soil amendments as well as the use of bioagents in sustainable agriculture, this research aimed to reduce the pesticide use in control of root-knot nematode, Meloidogyne javanica in tomato. Three separate experiments were performed to determine the effects of M. anisopliae IMI 330189 and different levels of oak tree debris on M. javanica. In the first and the second experiments, the effective method of application of M. anisopliae IMI 330189 and the effect of different rates of debris of oak trees were evaluated, respectively. In third experiment which was replicated two times, the combination effects of both of the factors, the fungus as well as the different rates of soil amendments were determined. Pots were filled with pasteurized soil mixture and the six leaves tomato seedlings were inoculated with 3000 second stage larvae of M. javanica/kg of soil. Eight weeks after treatment, plant growth and nematode reproduction factors were compared. Based on the results of the first experiment, soil drench application of M. anisopliae IMI 330189 suspension was selected for use in the other treatment. In the second experiment, statistical analysis revealed that, those inoculated tomato plants which were cultivated in pots with 150g oak debris/kg soil, received the minimum nematode damage. Both replicates of experiment three had the same results. In both runs of the experiment three, combination of M. anisopliae IMI 330189 and oak debris at the rates of 100 and 150g/kg soil, were the best treatments, which caused more than 90% reduction in reproduction factor of nematode (P≤0.05). As compared to control, reductions in number of galls were 55%, 50% and 76%, in experiments 1, 2 and 3 respectively. It was 71%, 72% and 86% for nematode reproduction factor, showing the significance of combined effect of both tested agents.
Analysis of the influence of waste polymer on soil subgrade

---------------------------------------------------------------------***--------------------------------------------------------------------Abstract This project is an attempt to understand the strength of subgrade in terms of CBR values and the corresponding variation in moisture content and to demonstrate the potential of high density polyethylene waste plastic fibres (HDPE) as soil reinforcement for improving engineering performance of subgrade soil. With this, a series of California Bearing Ratio (CBR) tests were carried out randomly reinforced soil in which the percentage of waste plastic fibres with different lengths and proportions (0 to 6 %) were carried on. The Indian Road Congress (IRC) encodes the exact design strategies of the pavement layers based upon the subgrade strength which is primarily dependent on CBR value for a laboratory. The results and conclusions were made which shows that use of waste plastic fibres in soil in an appropriate amount really aids in improving the strength of soil and also helps in modification of soil properties. The reinforcement benefit increased with an increase in waste plastic fibre content and waste plastic fibre length. The proposed technique can be used to advantage in embankment/road construction. The material can be used in base courses in constructing rural roads over saturated clay, thereby leading to safe disposal of these waste plastic materials in an environment friendly manner.
Internet Addiction and Psychological Well-being among Youth of Kashmir

The present study was conducted with the aim to examine the relationship between internet addiction and psychological well-being among youth of Kashmir and to find out the difference in both addiction and psychological well-being among youth of Kashmir with respect to gender and residential status. 100 students studying in various colleges of two districts of Kashmir (Srinagar and Ganderbal) completed the Young’s Internet addiction test (Young, 1998) and Ryff’s Psychological well-being scale (Ryff, 1995). Results of the study revealed a significant negative correlation between internet addiction and psychological well-being among youth of Kashmir. Further it was found that there is significant difference in internet addiction among youth of Kashmir with respect to their gender, males were found to be high on internet addiction than their counter parts and no significant difference was found in internet addiction with respect to their residential status. Results also revealed insignificant difference in psychological well-being among male and female youth and regarding their residential status significant difference was found in psychological well-being, urban youth were found to be high on the levels of psychological well being as compared to rural youth. The study will be helpful in highlighting the effect of internet addiction among youth which is becoming a menace day by day for society.