Miracle-dz/UniFAR-FTUs huggingface dataset:
Fishery of flying fish (Exocoetidae) in west coast of Surigao del Norte, Philippines

This study was conducted within 1-year period to determine relative abundance, catch per unit effort and fecundity of Flying fish in West Coast of Surigao del Norte, Philippines. A total of 2,537 Flying fish individuals belonged to three (3) genera and 11 species were recorded. The yellow-wing Flying fish, C. poecilopterus was the most dominant and abundant species with 37.80% of the total sample gathered. November obtained the highest catch landings, 8,041.67 kg and CPUE, 15.11 kg∙boat -1 day -1 . The estimated total catch landing for the whole duration of the study has reached to 46,604.51 kg with a mean CPUE of 12.20 kg∙boat -1 day -1 . A significant linear relationship was observed between absolute fecundity and total length, body weight, ovary length and ovary weight of C. poecilopterus . Absolute fecundity varies from 7668±713 to 11218±769 with a mean of 9402±1827 eggs. The ova diameter is significantly increasing from 589.4±161. 5μm in September with a maximum diameter of 1416.7±54. 7μm in March and decrease slightly from the month of April to May. Similarly, the mean values of gonadosomatic index were recorded from September (5.84±0.64) to May (11.08±2.58) and also showed highest in March (13.18±2.01).
Nanomodulated electron beams via electron diffraction and emittance exchange for coherent x-ray generation

We present a new method for generation of relativistic electron beams with current modulation on the nanometer scale and below. The current modulation is produced by diffracting relativistic electrons in single crystal Si, accelerating the diffracted beam and imaging the crystal structure, then transferring the image into the temporal dimension via emittance exchange. The modulation period can be tuned by adjusting electron optics after diffraction. This tunable longitudinal modulation can have a period as short as a few angstroms, enabling production of coherent hard x-rays from a source based on inverse Compton scattering with total accelerator length of approximately ten meters. Electron beam simulations from cathode emission through diffraction, acceleration, and image formation with variable magnification are presented along with estimates of the coherent x-ray output properties.
Mithramycin-A Induced Toxicity in HepG2 Cells is mediated by Disruption of Calcium Homeostasis

Mithramycin A is a potent inhibitor of EWS-FLI1, a transcription factor implicated in Ewings sarcoma. However, a clinical trial initiated to evaluate its efficacy revealed hepatotoxicity at doses well below those required for inhibition of EWS-FLI1 activity. In the present study, we used a chemogenomic screen against gene deletion mutants of the yeast Saccharomyces cerevisiae to generate hypothesis on its cellular mechanism of hepatotoxicity. Our findings show that it disrupts calcium homeostasis in S. cerevisiae . Studies in HepG2 cells grown in monolayer and as spheroids confirmed that it not only induced sustained elevated cytosolic Ca 2+ levels but also induced endoplasmic reticulum stress. Cells exposed to the compound were ultimately found to undergo calpain mediated apoptosis. These data suggest that mithramycin A is a direct toxin to liver cells and its toxicity is mediated, at least in part, by disruption of Ca 2+ homeostasis.
An investigation of the stability of the Bondi-Hoyle model of accretion flow. [onto massive astronomical bodies at high Mach number

The Bondi-Hoyle-Lyttleton (1944) accretion model is considered which involves accretion onto a massive body moving at a high Mach number with respect to the ambient medium and the production of a high-density accretion column along the axis where particle orbits intersect. The stability of steady-state solutions with respect to short-wavelength perturbations is analyzed using the WKB approximation, and the accretion column is shown to be unstable toward such perturbations. It is noted that this instability is not affected by the position of the stagnation point in the steady-state solution.
T HE E FFECTS OF O ZONE E XPOSURE ON A GED S OYBEAN S EEDS S TORED IN D IFFERENT P ACKAGING

This article is an open-access article distributed under the terms and conditions of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0) Abstract This article describes an idea about improving the aged soybean seed quality through ozone application based on the consideration that the ozone's oxidative and reactive nature could preserve agriculture commodities during storage. Using soybean seeds that were naturally aged in room temperature storage (25±5°C) for two months, gaseous ozone's efficacy in rejuvenating the aged seeds was examined. The aged seeds were divided into three different packages: open container, polypropylene woven sack, and vacuum polyethylene plastic. Gaseous ozone at a capacity of 150 g/h was continuously exposed on packaged seeds during six months of storage under low temperature (18±5°C). The authors found that ozone in specific limit exposure could improve physiological characteristics and inhibit some chemical properties deterioration of aged soybean seeds during storage. Our technique allows for improvement in germination percentage and germination rate of aged seeds in the fourth month of ozone exposure (p<0.05). However, these physiological parameters decreased significantly in the sixth month of ozone exposure, signing that prolonged ozone exposure would lead to adverse effects due to excessive oxidation. The result also showed that ozone storage significantly retard the elevation of moisture and free fatty acid content of aged soybean seeds. The ozone effectiveness evaluation is confirmed in all packaging conditions, but the vacuum packaging offered better preservation on almost entirely seed quality parameters during storage, except for protein. This research result provides a promising technique to restore aged seed quality and can be used for better seed provision in the seed industry.
Diversity, climate and innovative work behavior Innovative work behavior

Purpose – The purpose of this paper is to extend current discussion on the drivers of innovative work behavior (IWB) by exploring how individual perceived diversities (visible dissimilarity and cognitive group diversity) and climates (team/clan and innovative/entrepreneurial) impact IWB. Design/methodology/approach – Data had been collected from a cross-national study of working professionals ( n 5 584) from five different cultural contexts. Findings – Findings of this study indicated that cognitive group diversity mediated the negative relationship between visible dissimilarity and IWB. Further, both innovative/entrepreneurial and team/clan climates moderated the relationship between visible dissimilarity and cognitive group diversity. Such a moderation effect reduced the negative effect that visible dissimilarity had on IWB. Research limitations/implications – A cross-sectional single-source data set. Practical implications – From a managerial perspective, climates (team/clan and innovative/ entrepreneurial) are central for IWB in the diverse (visible and cognitive) working environment. Thus, organizations should pay attention to create a climate (team/clan or/and innovative/entrepreneurial) that reduces the negative impact of perceived diversity in the working environment while supporting IWB. Originality/value – Thisstudyisthefirstofitskindthatisbasedonsocialcategorizationtheory,empirically examininghowdifferenttypesofdiversity(visibledissimilarityandcognitivegroupdiversity)simultaneouslyreduceindividuals ’ IWB. Furthermore, this paper provides insights that climates (team/clan and innovative/ entrepreneurial) are crucial for IWB in the diverse working environment.
(2019). Plasma fucosylated glycans and C-reactive protein as biomarkers of HNF1A-MODY in young adult–onset nonautoimmune diabetes. (1), 17-26.

Objective Maturity-onset diabetes of the young due to variants in HNF1A is the commonest type of monogenic diabetes. Frequent misdiagnosis results in missed opportunity to use sulphonylureas as first-line treatment. A non-genetic biomarker could improve selection of subjects for genetic testing and increase diagnosis rates. We have previously reported that plasma levels of antennary fucosylated N -glycans and hsCRP are reduced in individuals with HNF1A-MODY. In this study, we examined the potential use of N glycans and hsCRP in discriminating individuals with damaging HNF1A alleles from those without HNF1A variants, in an unselected population of young adults with nonautoimmune diabetes. We analysed plasma N -glycan profile, measured hsCRP and sequenced HNF1A in 989 individuals with diabetes diagnosed below age 45, persistent endogenous insulin production and absence of pancreatic autoimmunity. Systemic assessment of rare HNF1A variants was performed. -glycans hsCRP
Differentiating Between Intentional Versus Unintentional Weight Loss

We read with particular interest the article by Martel et al exploring associations between obesity, weight change, and survival in patients with HER2-positive early breast cancer in the ALTTO trial. The authors main findings were 2-fold: (1) obesity at randomization was associated with worse distant disease-free survival (DDFS) and overall survival (OS), and (2) weight loss $5% at 2 years after randomization was associated with poorer DFS, DDFS, and OS. Although the first finding is consistent with previously published metaanalyses, we have concerns regarding the authors’ discussion of the second result and believe a more thorough explanation is warranted to minimize misinterpretations that could negatively impact clinical recommendations. The authors noted that intentional versus unintentional weight loss would have been informative for this study, but was unavailable. We wanted to clarify that not differentiating between how weight loss was achieved is a crucial missing data point that ultimately obscures their conclusion. Weight loss after diagnosis among patients with breast cancer, induced by healthy diet and exercise, has favorably impacted treatment-related adverse effects, quality of life, body composition measures, and serum inflammatory and metabolic biomarkers.34 Comparatively, weight loss potentially from underlying disease can result in sarcopenia (loss of muscle mass), which is associated with increased risk of mortality among patients with early breast cancer. It is also important to note the significant impact of weight loss was only observed among premenopausal women, and therefore any clinical implications these results may have should be carefully considered in this context. Based on their results, the authors also called for “caution if weight loss trials, such as the ongoing phase III Breast cancer WEight Loss study (BWEL), are to be conducted in survivors of HER2-positive breast cancer. ” However, because BWEL is a supervised weight loss intervention, we do not believe the results by Martel et al should be directly extrapolated to BWEL nor similar lifestyle interventions exploring the impact of intentional weight loss on DFS. We commend the authors for investigating these associations among a lesser studied breast cancer subtype and agree that dietary and exercise counseling should be part of survivorship care programs. However, we felt it was necessary to express our concerns about some of the conclusions, because they may unintentionally impact evidence-based research promoting weight loss through exercise and diet for patients with breast cancer and obesity. We hope future studies can differentiate how weight loss is achieved to further clarify these results. Leah Puklin, MPH; Melinda L. Irwin, PhD, MPH; Tara Sanft, MD; and Leah M. Ferrucci, PhD, MPH Yale School of Public Health, Yale Cancer Center, and Yale School of Medicine, Yale University, New Haven, Connecticut Email: Leah.puklin@yale.edu
Are mothers better at handling expenditures in stressful situations? Evidence from an Unconditional Cash Transfer in Indonesia

This paper analyses the eﬀect of a speciﬁc unconditional cash transfer in Indonesia on consumption, nutrition, and labor markets. I implement two diﬀerent methodologies to disentangle the real eﬀect of the cash transfer on recipients from the indirect eﬀect arising from poor households not receiving the transfer. Findings suggest that, while the cash transfer does not signiﬁcantly raise the consumption level of recipients, poor households not beneﬁting from the transfer suﬀer from acute liquidity constraints in terms of food expenditures. When household consumption and food expenditure decisions are made by mothers, the eﬀect of liquidity constraints is stronger for overall consumption expenditure but weaker for food expenditure, implying that credit constrained mothers are willing to give up non-food components of consumption to beneﬁt household nutrition. On the other hand, the cash transfer does not signiﬁcantly aﬀect hours worked.
High Risk for Obstructive Sleep Apnea in Chronic Treatment-Resistant Depression

Objectives: Studies have reported a higher risk for obstructive sleep apnea (OSA) in major depressive disorder (MDD). However, the risk of OSA in patients with chronic treatment-resistant depressive symptoms is not well documented worldwide. Hence, the current study assessed the risk of OSA and associated factors in patients with chronic treatment resistant depression (cTRD). Methods: The study recruited 140 Iranian patients with cTRD. All patients completed the Berlin questionnaire, which evaluates the riskof OSA.Additionally,demographicdataandhistoryof cardiovascularormetabolicdiseaseswerecollected. Pearson’sChi-square test, Fisher’s exact test, and independent T-test were used to assess group diﬀerences, when appropriate. Results: The study found that 89 of 140 cTRD patients (64%) were at high risk for OSA. Group comparison between cTRD patients (highvs. lowriskforOSA)demonstratedthatathighriskOSA-cTRDpatientshadanelevatedrateof hypertension,diabetesmellitus, andobesity. Also,age,durationof depression,anddurationof treatmentweresigniﬁcantlyhigherincTRDpatientswithhigherrisk compared to those with lower risk for OSA. Conclusions: The results suggest that a noticeable number of patients with cTRD are at high risk for OSA, which is higher than the reportedmagnitudeinthegeneralpopulation. Moreover,hypertension,diabetesmellitus,andobesityareassociatedwithahigher risk for OSA. Also, age, treatment duration, and depression duration could be considered as possible comorbid factors for OSA in patients with cTRD.
(2018). Evidence of negative affective state in Cavalier King Charles Spaniels with syringomyelia. Applied Animal

23 Syringomyelia is a common and chronic neurological disorder affecting Cavalier King Charles 24 Spaniels. The condition is putatively painful, but evaluating the affective component of chronic pain 25 in non-human animals is challenging. Here we employed two methods designed to assess animal 26 affect – the judgement bias and reward loss sensitivity tests – to investigate whether Cavalier King 27 Charles Spaniels with syringomyelia (exhibiting a fluid filled cavity (syrinx) in the spinal cord of ≥2mm 28 diameter) were in a more negative affective state than those without the condition. Dogs with 29 syringomyelia did not differ in age from those without the condition, but owners reported that they 30 scratched more (P<0.05), in line with previous findings. They also showed a more negative 31 judgement of ambiguous locations in the judgement bias task (P<0.05), indicating a more negative 32 affective state, but did not show a greater sensitivity to loss of food rewards. These measures were 33 unaffected by whether the dog was or was not receiving pain-relieving medication. Across all 34 subjects, dogs whose owners reported high levels of scratching showed a positive judgement bias 35 (P<0.05), indicating that scratching was not directly associated with a negative affective state. Tests 36 of spontaneous behaviour (latency to jump up to or down from a 30cm high platform) and 37 physiology (thermography of the eye) did not detect any differences. These results provide initial 38 evidence from the judgement bias task that syringomyelia may be associated with negative affect in 39 dogs, and open the way for further and larger studies to confirm findings and investigate the effects 40 of medication in more detail.
Issues Needing Clariﬁcation Regarding Population Characteristics in the Analysis From the National Cardiovascular Data Registry

1. Larsen S, Stride N, Hey-Mogensen M, et al. Simvastatin effects on skeletal muscle: relation to decreased mitochondrial function and glucose intolerance. J Am Coll Cardiol 2013;61:44–53. 2. Bruckert E, Hayem G, Dejager S, Yau C, Begaud B. Mild to moderate muscular symptoms with high-dosage statin therapy in hyperlipidemic patients—the PRIMO study. Cardiovasc Drugs Ther 2005;19:403–14. 3. Chew GT, Watts GF. Coenzyme Q10 and diabetic endotheliopathy: oxidative stress and the “recoupling hypothesis. ” QJM 2004;97:537–48. 4. Marcoff L, Thompson PD. The role of coenzyme Q10 in statinassociated myopathy: a systematic review. J Am Coll Cardiol 2007;49: 2231–7. 5. Young JM, Florkowski CM, Molyneux SL, et al. Effect of coenzyme Q(10) supplementation on simvastatin-induced myalgia. Am J Cardiol 2007;100:1400–3. 6. Maningat P, Breslow JL. Needed: pragmatic clinical trials for statinintolerant patients. N Engl J Med 2011;365:2250–1.
INDIVIDUALIZED PERIOPERATIVE RESPIRATORY SUPPORT AS A WAY OF PREVENTING POSTOPERATIVE PULMONARY COMPLICATIONS IN ABDOMINAL SURGERY

Introduction. Indicators of postoperative pulmonary complications (PPCs) in abdominal surgery being in the range of 17% to 88%, their development leads to an increase in morbidity and mortality, an extension in the length of stay in the medical institution, as well as material costs. In recent years, there has been a clear shift in the paradigm from the prevention of death and complications caused by lungs damage the prevention of the development of the complication. Prevention of pulmonary complications should have a comprehensive approach, but there is still no clearly formulated perioperative tactic for the management of patients with moderate or high risk of trouble development and with healthy lungs, taking into account the individual peculiarities of pulmonary tissue. Objective. To create and evaluate of the effectiveness of perioperative individualized respiratory support in patients with moderate or high risk of development of postoperative pulmonary complications the number of atelectasis, pneumonia and pleural effusion development after the upper floor of the abdominal cavity open surgical interventions.
Relation between Plasma Enterodiol and Enterolactone and Dietary Intake of Lignans in a Dutch Endoscopy-Based Population 1,2

Enterolignans are phytoestrogenic compounds derived from the conversion of dietary lignans by the intestinal microﬂora that may be protective against cardiovascular diseases and cancer. To evaluate the use of enterolignans as biomarkers of dietary lignan intake, we studied the relation between plasma and dietary lignans. We determined the dietary intake of 4 lignans (secoisolariciresinol (SECO), matairesinol (MAT), pinoresinol, and lariciresinol) using the European Prospective Investigation into Cancer and Nutrition FFQ, and plasma enterodiol (END) and enterolactone (ENL) concentrations were determined by liquid chromatography-tandem mass spectrometry. The population consisted of 637 men and women, aged 19-75 y, participating in a case-control study on colorectal adenomas. Participants did not use antibiotics in the preceding calendar year. We found a modest association between lignan intake and plasma END (Spearman r ¼ 0.09, P ¼ 0.03) and ENL (Spearman r ¼ 0.18, P , 0.001). The correlation of total lignan intake with plasma enterolignans was slightly stronger than that of only SECO plus MAT. The plasma concentrations of both END and ENL were associated with intakeofdietaryﬁberandvegetableproteinbutnotwithintakeofothermacronutrients. Therelationbetweenlignanintakeand plasma END was modulated by age and previous use of antibiotics, whereas for ENL, it was modulated by weight, current smoking,andfrequencyofdefecation.However,evenwhenweincludedthesenondietaryfactorsintheregressionmodels, the explained variance in plasma END and ENL remained low (2 and 13%, respectively). J. Nutr. 137: 1266–1271, 2007. P , 0.05) in the full model for END or ENL, and energy intake. Dietary lignans, ﬁber, major energy-providing nutrients, and major food sources of lignans were considered as potential dietary determinants of plasma enterolignan concentrations. We used 1 SD change in intake of potential dietary determinants to estimate the associated change in plasma enterolignan concentrations. Statistical analyses were performed using SAS software (version 9.1, SAS
University of Birmingham On the relation between graph distance and Euclidean distance in random geometric graphs

Given any two vertices u, v of a random geometric graph G ( n, r ), denote by d E ( u, v ) their Euclidean distance and by d G ( u, v ) their graph distance. The problem of ﬁnding upper bounds on d G ( u, v ) conditional on d E ( u, v ) that hold asymptotically almost surely has received quite a bit of attention in the literature. In this paper, we improve the known upper bounds for values of r = ω ( √ log n ) (i
A DESCRIPTIVE RESEARCH ON THE INCIDENCE OF PREGNANT WOMEN ’ S ANXIETY AND DEPRESSION IN THE LIGHT OF INTERNATIONAL DISEASE CLASSIFICATION HELD AT SERVICES HOSPITAL, LAHORE

: Objective : The study was aimed at finding out the causes of dejection and restlessness in the pregnant women at a teaching hospital ’ s out patient department. The patients presented in the obstetrics department were analyzed for the depression and anxiety during the pregnancy period. The associated risk factors and psychiatric issues among pregnant women were also discussed in our analysis. Design : The design of the study was descriptive and it consisted of two hundred patients. Subjects and methods : The sample consisted of two hundred patients from OPD of Services Hospital, Lahore (May, 2017 – October 2017). The subjects were selected on the basis of inclusion criteria and interview. Socio-economic details for each patient were recorded. Present State Exam (approved by WHO for assessment of current state of psychiatric patients) was utilized to interview the subjects and ICD-10 was used to evaluate the overall diagnosis. Results : The results were compiled in light of International Classification of Diseases and showed that gravid women were the victims of depression and anxiety (25% and 34.5% respectively). The risk factors accounted for dejection and discomfort were multiple like early marriages, death of parents in childhood, psychiatric illness / family history. Conclusion : The incidences of dejection and discomfort among pregnant women are found everywhere in the world. The need is to filter out the women who possess the possible risk factors for depression and anxiety and formulate the local procedures which improve the mental condition of the psychiatric gravid patients