Miracle-dz/UniFAR-FTUs huggingface dataset:
Mechanisms of Diet-induced Dyslipidemia and Insulin Resistance: Role of Chronic LXR Activation

The metabolic syndrome is a collection of pathologies including dyslipidemia, obesity and insulin resistance. A thorough understanding of the mechanisms behind metabolic syndrome development would help in the development of treatment and prevention strategies. Our lab has previously shown that cholesterol feeding exacerbates features of the metabolic syndrome in high fat-, high fructose-fed mice. The nuclear receptor Liver X Receptor (LXR), a master transcriptional regulator of cholesterol, fat and carbohydrate metabolism in the liver, is endogenously activated by oxysterols, metabolic derivatives of cholesterol. In order to determine whether cholesterol exerts its metabolic effects via LXR activation, parallel studies were conducted comparing chronic cholesterol supplementation with LXR activation in the hamster. Results showed that cholesterol feeding and LXR activation caused similar dyslipidemia, glucose intolerance and upregulation of target mRNA and proteins. These data support the hypothesis that the dyslipidemic effects of dietary cholesterol are mediated at least in part by LXR.
Making Sense of “Good” and “Bad”: A Deonance and Fairness Approach to Abusive Supervision and Prosocial Impact

This article challenges the unidimensional view of abusive supervisors and examines how employees respond to abuse when the transgressing boss also has a positive impact on others. Drawing on deonance and fairness theory, we propose competing hypotheses about the influence of prosocial impact. Specifically, we use deonance theory to suggest that prosocial impact might buffer the effects of abusive supervision. Alternatively, we incorporate fairness theory to predict that prosocial impact strengthens injustice perceptions and thereby worsens consequences of abuse. Two field studies show support for fairness theory, demonstrating that employees perceive greater injustice, and show stronger retaliatory behaviors, when the abusive supervisor makes a positive difference in the workplace. A final field study replicates these results, while also testing the underlying cognitive process employees use to assess the interplay between “good” and “bad” supervisory characteristics. This article contributes insights to abusive supervision, prosocial impact, organizational justice, and behavioral ethics literatures.
Multilevel Analysis of Social and Policy Acceptance of Immigrants across European Countries and Its Implications for Comparative Policy

Abstract With the influx of African and Middle Eastern refugees to Europe, the interest in immigrants has increased. This study analyzes how individual-level and country-level variables affect social and policy acceptance. It finds that personal ties and life satisfaction determine acceptance. Also, individual and contextual variables influence acceptance. Direction and significance of the predictor’s impact depends on each national context. Skilled labor (+), ideology (left, +), knowledge (+), government spending (–), and crime rate (–) only affect social acceptance whereas social contact (+), unemployment rate (–), party seats of left/socialist (+), and ethnic diversity (+) affect policy.
Revisiting smart antenna array design with multiple interferers using basic adaptive beamforming algorithms: Comparative performance study with testbed results

Smart antennas are becoming popular in the area of cellular wireless communication for capacity enhancement and reduction of the multipath effect and interference. The demand for smart antennas is widely increasing as 5G cellular communication evolves to support the higher data rate and bandwidth. The basic principle of smart antenna design is adaptive beamforming using the best suited digital signal processing algorithms, such as least mean square (LMS), normalized least mean square (NLMS), sample matrix inversion (SMI), and recursive least square (RLS), each having its pros and cons. Among these, the LMS and NLMS are iterative approaches while SMI is a block adaptive method and RLS is a recursive method. The contribution of this article includes easy implementation of four adaptive beamforming algorithms, namely LMS, NLMS, SMI, and RLS. Furthermore, an exhaustive comparative performance analysis is carried out under five interferers and evaluated in terms of beamwidth, null depth, maximum sidelobe level, rate of convergence, error variation for the number of antenna elements, and spacing. Finally, a contrast table is presented to demonstrate the pros and cons of the listed algorithms. Time and dynamic space complexity are studied for RLS and SMI beamforming algorithms. Performance results from a designed reconfigurable testbed model for weight adaptation and smart beamforming are also presented for analysis and a better understanding of the real implementation of the smart algorithms through testbed design. The simulation and testbed results create the ground work for future exploration in the design of smart antenna beamforming.
Once-Daily Low Inflammatory Foods Everyday (LIFE) Smoothie or the Full LIFE Diet Lowers C-Reactive Protein and Raises Plasma Beta-Carotene in 7 Days

Serum C-reactive protein (CRP), a marker of systemic inflammation, is associated with increased risk for numerous inflammation-driven chronic diseases. A prior longitudinal study showed that the Low Inflammatory Foods Everyday (LIFE) diet, which is rich in dark green leafy vegetables (DGLV), lowered CRP over a mean follow-up period of 6 months. In this retrospective study, we investigate whether patients who consume the LIFE diet or their regular diet plus one component of the LIFE diet (LIFE smoothie), experience reductions in high-sensitivity CRP (hsCRP) in 7 days. Sixteen patients in a community practice met inclusion criteria. Patient compliance was assessed by patient interviews and measurements of beta-carotene, which is abundant in DGLV. Following the interventions, CRP decreased in both the LIFE diet (−0.47 mg/L, P = .02) and smoothie groups (−1.2 mg/L, P = .04). No statistically significant difference in reduction was observed between groups (P = .18). Plasma beta-carotene increased in both groups (+23.2, P = .02; +20.6, P = .006, respectively). These findings suggest that the LIFE diet or a regular American diet supplemented with the LIFE smoothie may quickly reduce systemic inflammation and the risk of many chronic diseases.
Simultaneous multiple MS binding assays targeting the monoamine transporters hDAT, hNET, and hSERT

MS Binding Assays represent a label free alternative to radioligand binding assays. In this study, we present an LC-ESI-MS/MS method for the quantification of (R,R)-4-(2benzhydryloxyethyl)-1-(4-fluorobenzyl)piperidin-3-ol ((R,R)-D-84, (R,R)-1), (S,S)-reboxetine ((S,S)-2), and (S)-citalopram ((S)-3) employed as highly selective nonlabelled reporter ligands in MS Binding Assays addressing the dopamine (DAT, (R,R)-D-84), the norepinephrine (NET, (S,S)-reboxetine), and the serotonin transporter (SERT, (S)-citalopram), respectively. Page 1 of 61 http://mc.manuscriptcentral. com/bmc Biomedical Chromatography 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60
Two Complete Spectral Transitions of Swift J0243.6+6124 Observed by Insight-HXMT

We performed the broadband (1–100 keV) spectral analysis of the first Galactic Be ultraluminous X-ray pulsar (BeULX) Swift J0243.6+6124 observed by Insight-HXMT during the 2017−2018 outburst. The results show spectral transitions at two typical luminosities, roughly consistently with those reported previously via pure timing analysis. We find that the spectrum evolves and becomes softer and has higher cutoff energies until the luminosity reaches L1 (∼1.5 × 1038 erg s−1). Afterwards the spectrum becomes harder with lower cutoff energies until the luminosity increases to L2 (∼4.4 × 1038 erg s−1), around which the second spectral transition occurs. Beyond L2, the spectrum softens again and has larger cutoff energies. Similar behaviors were observed previously in other high-mass X-ray binary systems (HMXBs), especially for the second transition at higher luminosities, which is believed to have a correlation with the magnetic field of the harbored neutron star. Accordingly, we speculate that Swift J0243.6+6124 owns a neutron star with magnetic field strength >1013 G. The spectral transition at around L1 of Swift J0243.6+6124 is first observed thoroughly for any HMXB outburst characterized by strong evolution of the thermal component: the temperature of the blackbody drops sharply accompanied by a sudden increase of the blackbody radius. These spectral transitions can in principle be understood in a general scenario of balancing the emission patterns between the pencil and the fan beams at the magnetic pole, for which the extreme brightness of Swift J0243.6+6124 may provide an almost unique lab to probe the details.
NOR Polymorphism and Chromosome Analysis of Banggai Cardinalfish, Pterapogon kauderni (Perciformes, Apogonidae)

1 Department of Aquatic Science, Faculty of Science, Burapha University, Muang, Chonburi 20131, Thailand 2 Institute of Marine Science, Burapha University, Muang, Chonburi 20131, Thailand 3 Department of Biology, Faculty of Science, Burapha University, Muang, Chonburi 20131, Thailand 4 Department of Fundamental Science, Faculty of Science and Technology, Surindra Rajabhat University, Muang, Surin 32000, Thailand 5 Faculty of Applied Science and Engineering, Khon Kaen University, Nong Kai Campus, Muang, Nong Kai 43000, Thailand 6 School of Agricultural of Technology, Walailak University, Thasala, Nakhon Si Thammarat 80160, Thailand 7 Toxic Substances in Livestock and Aquatic Animals Research Group, Department of Biology, Faculty of Science, Khon Kaen University, Muang, Khon Kaen 40002, Thailand
Non-/Human Infrastructures and Digital Gifts: The Cables, Waves and Brokers of Solomon Islands Internet

ABSTRACT This article demonstrates how nonhuman and human infrastructural assemblages, and the brokers that operate as assemblers within them, give rise to localised Internets. With an ethnographic emphasis on the digital transformations of Solomon Islands, we examine agentive brokerage practices surrounding digital multimedia files, downloaded off the global Internet and circulated offline as gifts via MicroSDs. We show how digital brokers use their comparatively unique manoeuvrability within digital infrastructural assemblages. They extend the Internet to offline rural environments, while following and strengthening local systems of moral economic social reproduction. Recognising the interconnectedness of human and nonhuman actors, these brokers are also dependent on the broader infrastructural assemblages in which they operate, especially the cables and waves that initially allow digital bits to travel to Solomon Islands. Localised Internets such as Solomon Islands are, thus, continuously in flux, being perpetually reassembled by the agentive practices of their constituent parts.
Analytical Fast Magnetosonic Wave Model Based on Observations of Van Allen Probe

Based on observations of Van Allen Probe‐A during the period from 19 September 2012 to 28 February 2016, the relations of the fast magnetosonic (MS) wave amplitude Bw with kp index, the wave normal angle (WNA), and the wave normalized frequency (norF) are presented. Then, we establish an analytical regression model for MS wave amplitude as a function of geomagnetic storm activity (presented by kp index), L‐shell (L), magnetic local time (MLT), magnetic latitude (λ), and the characteristics of MS wave, that is, wave norF and WNA. From the analytical Bw models, we found MS wave amplitude Bw has a positive relation with the intensity of geomagnetic activities both inside and outside the plasmapause, while the Bw can reach higher values inside the plasmapause than it does outside the plasmapause as the kp index increases. The Bw distribution on the norF demonstrates that most of the wave energies are concentrated on the lower harmonics part, which results from the excitation mechanism of MS waves. In addition, the Bw distribution on the WNA shows that the waves with larger normal angles have higher values of wave amplitude. Our analytic MS wave model agrees with the observed distribution in 3‐D space of L, MLT, and λ well with high value of determine coefficient R2. The extended λ dimension will help us to calculate the more accurate bounced averaged diffusion coefficients during particles transit time.
Asymmetric competition for light varies across functional groups

Aims Asymmetric competition for light may depress the growth rates (GRs) to different extents for different-sized tree individuals. Various responses of different functional groups to light availability result that tree individuals of different functional groups may experience different competition intensities, e.g. canopy and deciduous species grow faster and demand more light than understory and evergreen species. In this study, we estimated the effects of asymmetric competition for light using individual GRs and explored the effects of asymmetric competition on growth among different functional groups (e.g. canopy vs. understory species and deciduous vs. evergreen species). Methods We measured growth in circumference to determine the radial increments of a total of 2233 stems with diameter at breast height ≥ 5.0 cm in a permanent plot (140 × 80 m2) located in a typical evergreen and deciduous broadleaved mixed forest on Mt Shennongjia, China. All of the measurements were carried out at ~6-month intervals every April and October from 2012 to 2014, and biomass of each individual was calculated based on its diameter and species-specific allometry. We then calculated GRs of annual biomass growth (growth between October and the next October). Considering the hypothesis that asymmetric competition for light among trees of different sizes may result in a steeper allometric growth curve with increasing tree size, we further divided the sampled trees into different subsets according to their height, at intervals of 1 m, and then fitted the scaling relationship between the logarithm of the biomass GR (logGR) and the logarithm of diameter (logD) for each height class using standardized major axis regression. Finally, we used simple linear regression to test whether the scaling exponent was related to tree height. The above analyses were conducted for the annual growth of all tree species, canopy species, understory vs. treelets species and deciduous vs. evergreen species. Important findings We observed a concave curve for the relationship between logGR and logD with an increase in the scaling exponent between logGR and logD with increasing tree height. This pattern held for the annual growth of canopy species and deciduous species but not for the annual growth of understory species, treelets or evergreen species. These results suggest that asymmetric competition for light is more important in regulating the GRs of the fast-growing species, such as canopy species and deciduous species, than those of shadetolerant species, such as understory species, treelets and evergreen species.
A Review of Current Literature on sudden Upsurge of COVID-19

Since December 2019, a sequence of baffling pneumonia cases has been notified in Wuhan, China On 12 January 2020, this virus is temporarily named as 2019 novel coronavirus (2019-nCoV) On 11 February 2020, the disease caused by the virus has officially named as coronavirus disease (COVID‐19) by WHO The COVID‐19 pandemic is spreading all over the world, especially in China, Italy, America, and South Korea Established on the published data, we systematically confer the attributes of COVID‐19 in the aspiration of providing a quotation for future studies and thus support for the prevention and management of the COVID‐19 pandemic
Direct numerical simulation of subsonic, transonic and supersonic flow over an isolated sphere up to a Reynolds number of 1000

Abstract In the present study, compressible low-Reynolds-number flow past a stationary isolated sphere was investigated by direct numerical simulations of the Navier–Stokes equations using a body-fitted grid with high-order schemes. The Reynolds number based on free-stream quantities and the diameter of the sphere was set to be between 250 and 1000, and the free-stream Mach number was set to be between 0.3 and 2.0. As a result, it was clarified that the wake of the sphere is significantly stabilized as the Mach number increases, particularly at the Mach number greater than or equal to 0.95, but turbulent kinetic energy at the higher Mach numbers conditions is higher than that at the lower Mach numbers conditions of similar flow regimes. A rapid extension of the length of the recirculation region was observed under the transitional condition between the steady and unsteady flows. The drag coefficient increases as the Mach number increases mainly in the transonic regime and its increment is almost due to the increment in the pressure component. In addition, the increment in the drag coefficient is approximately a function of the Mach number and independent of the Reynolds number in the continuum regime. Moreover, the effect of the Mach and Reynolds numbers on the flow properties such as the drag coefficient and flow regime can approximately be characterized by the position of the separation point.
Investigating a theoretical framework for e-learning technology acceptance

E-learning has gained recognition and fame in delivering and distributing educational resources, and the same has become possible with the occurrence of Internet and Web technologies. The research seeks to determine the factors that influence students' acceptance of E-learning and to find out the way these factors determine the students' intention to employ E-learning. A theoretical framework was developed based on the technology acceptance model (TAM). To obtain information from the 270 university students who utilized the E-learning system, a questionnaire was formulated. The results revealed that “social influence, perceived enjoyment, self-efficacy, perceived usefulness, and perceived ease of use” are the strongest and most important predictors in the intention of and students towards E-learning systems. The outcomes offer practical implications for practitioners, lawmakers, and developers in effective E-learning systems implementation to improve ongoing interests and activities of university students in a virtual E-learning atmosphere, valuable recommendations for E-learning practices are given by the research findings, and these may turn out to be as guidelines for the efficient design of E-learning systems.
International entrepreneurship in small family firms: a cross-case analysis

Purpose of the paper: This study aims to identify the main drivers that spur family entrepreneurs to implement internationalization strategies in a social and geographical context that appears to be anchored in the past and does not stimulate business development overseas. Methodology : This study employs a cross-case analysis, which is the most suitable method to highlight similarities and differences across cases. In order to gather and analyze the data, this study adopted an inductive approach. Results : Novel best practices are revealed and help to enhance international entrepreneurship in a difficult setting of reluctance to change and loyalty to a past-anchored culture. Moreover, the findings show which elements encourage and discourage international entrepreneurship. Finally, the study offers an interpretive model derived for the interpretation of similar cases. Research limitations : The main drawback of the study is its explorative analysis of a small sample of family firms. Academic and practical implications: From a theoretical perspective, this study contributes to the literature on the international entrepreneurship of small family firms that are embedded in hostile contexts by identifying the main drivers that promote internationalization. For practitioners, this study offers best practices to inspire successful resilient behaviors and decisions for firms that desire to sell their products all over the world. Originality of the paper: The study elucidates the relevance of the family, firm and context as the main drivers in improving international entrepreneurship by balancing contextual obstacles with entrepreneurs’ ambitions of international growth and development.
Phase Separation and Pairing Fluctuations in Oxide Materials

The microscopic mechanism of charge instabilities and the formation of inhomogeneous states in systems with strong electron correlations is investigated. We demonstrate that within a strong coupling expansion the single-band Hubbard model shows an instability towards phase separation and extend the approach also for an analysis of phase separation in the Hubbard-Kanamori hamiltonian as a prototypical multiband model. We study the pairing fluctuations on top of an inhomogeneous stripe state where superconducting correlations in the extended s-wave and d-wave channels correspond to (anti)bound states in the two-particle spectra. Whereas extended s-wave fluctuations are relevant on the scale of the local interaction parameter U, we find that d-wave fluctuations are pronounced in the energy range of the active subband which crosses the Fermi level. As a result, low energy spin and charge fluctuations can transfer the d-wave correlations from the bound states to the low energy quasiparticle bands. Our investigations therefore help to understand the coexistence of stripe correlations and d-wave superconductivity in cuprates.
Demographic determinants of charity donors and its implication for cash waqf institutions in Malaysia

Purpose The purpose of this study is to identify the demographic groups that can be targeted for donations by the cash waqf institutions for their marketing campaigns in Malaysia. Design/methodology/approach This paper uses a structured questionnaire to acquire the understanding of Malays about the existence of poverty in Malaysia and to identify the demographic groups that can be targeted for the marketing campaigns of cash waqf institutions. The sample consisted of 430 Malays respondents residing in Selangor. The study used the methodology of Baron and Kenny for mediation analysis. Findings The finding indicates that Malays do hold sympathies towards the poor. Further investigation shows that high-income class and female are the two demographic groups that are more sympathetic towards the poor because of their strong belief in charity. Research limitations/implications The data collection is limited to Selangor only. However, it provides enough information about the demographic groups which is worth exploring for the future researchers in order to come up with marketing strategies related to cash waqf collections. Practical implications On the basis of findings, cash waqf institutions in Malaysia can come up with marketing strategies to attract high-income class and females as their potential donors. Originality/value The charity institution specifically cash waqf institutions in Malaysia are struggling to identify the right target groups for their marketing campaigns. This study used attribution theory to identify the target groups which is overshadowed by the previous research studies in the context of Malaysia.