Miracle-dz/UniFAR-FTUs huggingface dataset:
Investigation of post hydraulic fracturing well cleanup physics in the Cana Woodford Shale

Hydraulic fracturing was first carried out in the 1940s and has gained popularity in current development of unconventional resources. Flowing back the fracturing fluids is critical to a frac job, and determining well cleanup characteristics using the flowback data can help improve frac design. It has become increasingly important as a result of the unique flowback profiles observed in some shale gas plays due to the unconventional formation characteristics. Computer simulation is an efficient and effective way to tackle the problem. History matching can help reveal some mechanisms existent in the cleanup process. The Fracturing, Acidizing, Stimulation Technology (FAST) Consortium at Colorado School of Mines previously developed a numerical model for investigating the hydraulic fracturing process, cleanup, and relevant physics. It is a three-dimensional, gas-water, coupled fracture propagation-fluid flow simulator, which has the capability to handle commonly present damage mechanisms. The overall goal of this research effort is to validate the model on real data and to investigate the dominant physics in well cleanup for the Cana Field, which produces from the Woodford Shale in Oklahoma. To achieve this goal, first the early time delayed gas production was explained and modeled, and a simulation framework was established that included all three relevant damage mechanisms for a slickwater fractured well. Next, a series of sensitivity analysis of well cleanup to major reservoir, fracture, and operational variables was conducted; five of the Cana wells’ initial flowback data were history matched, specifically the first thirty days’ gas and water producing rates. Reservoir matrix permeability, net pressure, Young’s modulus, and formation pressure gradient were found to have an impact on the gas producing curve’s shape, in different ways. Some moderately good matches were achieved, with the outcome of some unknown reservoir information being proposed using the corresponding inputs from the history matching study. It was
Canine Distemper Virus in Wild Carnivore Populations from the Czech Republic (2012–2020): Occurrence, Geographical Distribution, and Phylogenetic Analysis

Canine distemper is a highly contagious viral disease in carnivores and represents a serious threat for both wild and domestic animals. The aim of our study was to monitor the occurrence of the canine distemper virus in wildlife from the Czech Republic, reveal the H gene heterogeneity in positive samples and perform subsequent phylogenetic analysis. In total, 412 wild animals of 10 species were included in the study: 219 red foxes (Vulpes vulpes), 79 European badgers (Meles meles), 47 European otters (Lutra lutra), 40 stone martens (Martes foina), 10 pine martens (M. martes), 7 raccoons (Procyon lotor), 5 undetermined martens (Martes sp.), 2 wolves (Canis lupus), 1 European polecat (Mustela putorius), 1 free-ranging ferret (Mustela putorius furo), and 1 free-ranging American mink (Neovison vison). Most animals were found dead or were killed by hunters during hunting seasons in the years 2012–2020 and came from all 14 regions of the Czech Republic. In the animals that were hunted, symptoms such as apathy, loss of shyness or disorientation were reported. Canine distemper virus (CDV) was detected by real-time RT-PCR in the tissues of 74 (18%) of the animals, including 62 (28%) red foxes, 4 (10%) stone martens, 3 (43%) raccoons, 2 (20%) pine martens, 2 (2.5%) European badgers and 1 (20%) undetermined marten. There was a statistical difference in positivity among animal species (p < 0.0001), regions (p = 0.0057), and the years of sampling (p = 0.0005). To determine the genetic characteristics of circulating variants of CDV in wildlife, 23 of 74 CDV variants were partially sequenced. Phylogenetic analysis showed that 21 variants belonged to the European lineage and two strains belonged to the European-Wildlife lineage. This study provides the first comprehensive overview of the prevalence and spatial distribution of CDV in wildlife in the Czech Republic, including molecular phylogenetic analysis of currently circulating CDV lineages.
Internationalizing Violence Prevention: East Asian Perspectives on Sex, Relationships, and Sexual Violence

Sexual violence prevention initiatives often do not address the unique experiences of international students. This study examined the experiences of eight East Asian international students navigating sex, relationships, and sexual violence in the United States. Four themes emerged: navigating a more open society without preparation, feeling pressure and choosing silence, searching for meaning and learning through example, and developing knowledge through interactions. These themes describe the students’ experiences and lead to implications for practice.
Does Union Canvassing Affect Voter Turnout Under Conditions of Political Constraint? Empirical Evidence from Illinois

The positive effects of union canvassing on individual-level union member voter turnout within union-friendly environments have been well documented. Yet, whether unions increase turnout among their membership under constrained circumstances has remained unexamined. Furthermore, there is little consensus on whether union canvassing effects are generalizable to populations with heterogeneous political attributes and individual characteristics. This paper identifies the mechanisms that might explain how union canvassing can be effective under conditions characterized by anti-union legislative actions, adversarial judicial decisions, and right-wing populist rhetoric. We use canvassing and turnout data taken from the 2016 Democratic state and Cook County primary election in Illinois, and our results show that, despite constrained political circumstances relative to those found in previous studies, union canvassing achieved positive union membership turnout effects. This study also tests the moderating effects of individual political attributes (ideology and vote propensity) and voter characteristics (income and ethnicity). The most salient finding is that the effects are more potent for ideologically conservative registered Democrat voters, highlighting the imperative of recognizing the ideological heterogeneity among union members and suggesting specific resource allocation strategies under politically constrained conditions.
Nerve sparing retroperitoneal lymph node dissection in clinical stage IIA/B seminoma: The COTRIMS trial.

418 Background: Retroperitoneal radiation therapy or systemic chemotherapy with 3 cycles PEB represent the guideline recommended treatment options in marker negative clinical stage IIA/B seminoma. Despite a high cure rate of 90% to 94% and 82% to 90% in CS IIA and IIB, respectively, both therapeutic options are associated with significant long-term toxicities. It was the aim of our trial to evaluate the feasibility, oncological efficacy and treatment associated morbidity of primary nsRPLND in stage IIA/B seminoma. Methods: 16 patients with marker negative clinical stage IIA and IIB classical seminoma of the testis were recruited in the prospective trial. Patients with primary metastatic stages IIA/B or patients who developed metastatic during active surveillance for clinical stage I seminoma could be recruited. Metastatic disease following carboplatin therapy for clinical stage I seminoma represented an exclusion criteria. Informed consent was obtained after educational talk about the standard treatment options. Surgery associated complications were classified according to Clavien-Dindo. Progression-free survival and overall survival were calculated by Kaplan-Meier curves. Results: Mean age was 37.2 (21-54) years. Mean follow-up is 21.2 (1-36) months. All patients were treatment-naïve and 9 (56.2%) and 7 (43.8%) patients were diagnosed with stage IIA/B at time of primary diagnosis or during active surveillance for clinical stage I disease, respectively. 13 (81.2%) and 3 (18.8%) patients were diagnosed with stage IIA and IIB disease, respectively. 14 (87.5%) and 2 (12.5%) patients underwent open and robot assisted ns RPLND, respectively. Mean OR time was 131 (105-195) min, mean blood loss was < 150ml and the mean hospitalization time was 4.5 (3-9) days. We did not observe surgery associated complications > Clavien Dindo grade 3a. 14/16 (87.5%) patients preserved antegrade ejaculation. Histology of the resected lymph nodes revealed metastatic seminoma in 12 (75%) patients; 1 and 3 patients demonstrated embryonal carcinoma and inflammatory disease, respectively. 2/16 (12.5%) patients developed an outfield relapse 4 and 6 months postoperatively. Both patients were salvaged by systemic chemotherapy with 4 cycles PEB. Conclusions: NsRPLND results in a high cure rate at midterm follow-up and it is associated with a low frequency of treatment associated morbidities making this approach a feasible alternative to standard radiation therapy or systemic chemotherapy. Clinical trial information: DRKS00025384.
Emergence of Nano-Dentistry as a Reality of Contemporary Dentistry

(1) Background. Nanotechnology offers significant alternative ways to solve scientific, medical, and human health issues. Dental biomaterials were improved by nanotechnology. It manufactures better materials or improves the existing ones and forms the basis of novel methods for disease diagnosis and prevention. Modern nanotechnology makes oral health care services more acceptable for patients. Nanotechnology is now important area of research, covering a broad range of applications in dentistry. (2) Methods. Relevant literature from Scopus published in English was selected using the keywords “nanoparticle” and “dentistry”. To the selected articles we applied the inclusion and exclusion criteria to choose the relevant ones. (3) Results. Based on the relevant articles, a literature review was prepared. This review provides an insight into the applications of nanotechnology in various branches of dentistry. We applied several regression models to fit number of papers versus time and chose the best one. We used it to construct the forecast and its 95%-confidence interval for the number of publications in 2022–2026. (4) Conclusions. It shows that a significant rise in papers is expected. This review familiarizes dentists with properties and benefits of nanomaterials and nanotechnology. Additionally, it can help scientists to consider the direction of their research and to plan prospective research projects.
PSMA PET and FDG PET as predictors of response and prognosis in a randomized phase 2 trial of 177Lu-PSMA-617 (LuPSMA) versus cabazitaxel in metastatic, castration-resistant prostate cancer (mCRPC) progressing after docetaxel (TheraP ANZUP 1603).

10 Background: The TheraP trial showed that LuPSMA improved PSA≥50% response rate (PSA50-RR), PSA-PFS, and radiographic PFS (rPFS) compared with cabazitaxel in mCRPC progressing after docetaxel. Study inclusion required high PSMA uptake (SUVmax≥20) and no lesions that were FDG+ and PSMA-. Here we report on PSMA PET and FDG PET as potential predictive and prognostic biomarkers. Methods: We prospectively analysed semi-automated quantitative PET parameters in centrally- collected 68Ga-PSMA-11 PET and 18F-FDG PET in 200 eligible men. SUVmean ≥10 on PSMA PET was evaluated as a predictive biomarker for response to Lu-PSMA vs cabazitaxel. Metabolic tumor volume (MTV) ≥200mL on FDG PET was tested as a prognostic biomarker accounting for the randomly assigned treatment. Quantitative PET cut-offs were pre-specified from prior research (PMID:32140802). Responses were defined according to PSA50-RR (primary endpoint), PSA-PFS and rPFS. Binary and PFS endpoints were analyzed using logistic and Cox regression, respectively. Results: Very high PSMA uptake on PSMA PET (SUVmean≥10) was seen in 35/99 (35%) assigned LuPSMA and 30/101 (30%) assigned cabazitaxel. The odds of a response to LuPSMA vs. cabazitaxel were significantly higher for men with SUVmean≥10 (OR 12.2, 95%CI 3.4-59 vs. 2.2, 95%CI 1.1-4.5; p = 0.03). In men with SUVmean≥10, the PSA50-RR for LuPSMA vs. cabazitaxel were 32/35 (91%) vs. 14/30 (47%). In men with PSMA SUVmean < 10, the PSA50-RR were 33/64 (52%) vs. 23/71 (32%). High-volume metabolic disease on FDG PET (MTV ≥200mL) was seen in 30/99 (30%) assigned LuPSMA and 30/101 (30%) assigned cabazitaxel. The PSA50-RR in these men was 17/30 (57%) for LuPSMA vs. 6/30 (20%) for cabazitaxel. In comparison, the PSA50-RR for men with MTV < 200mL on FDG PET was 48/69 (70%) for LuPSMA vs. 31/71 (44%) for cabazitaxel. After accounting for treatment, the odds of a PSA50-response was lower among men with high MTV (OR 0.44; p = 0.01). The HR for PSA-PFS for LuPSMA vs cabazitaxel was 0.45 (95%CI 0.25-0.80) for SUVmean≥10 vs. 0.77 (95%CI 0.53-1.12) for SUVmean < 10 (p = 0.2). Findings were similar for rPFS. The HRs for high MTV on FDG PET adjusted for treatment were 1.44 (95%CI 1.03-2.02) for PSA-PFS (p = 0.03); and 1.79 (95%CI 1.28-2.52) for rPFS (p < 0.001). Conclusions: In men with mCRPC, PSMA SUVmean≥10 was predictive of a higher likelihood of favourable response to LuPSMA than cabazitaxel, whilst a high volume of disease on FDG PET was associated with a worse prognosis regardless of randomly assigned treatment. Clinical trial information: NCT03392428.
Interpersonal Violence in Chile, c. 1880s–2010s: A Tale of Delayed but Successful Convergence

Abstract We analyze the evolution of homicide rates in Chile, as a proxy of interpersonal violence, from the 1880s to the 2010s. Homicides rates are the best measure of a country’s personal security, and a key variable of well-being. We found that the homicides rates were high during the late nineteenth century and the early decades of the twentieth century. From the 1930s homicide rates started to decline initially gradually, but then sharply during the 1950s–1960s. During the 1960s–1990s, the country’s homicide rates were low by international standards. However, they have increased during the last two decades. Our regression suggests that increased social spending in the past is associated with reduced homicides in the present, that past and concurrent economic growth also correlates with a reduction in the rate of homicides, and that increased police presence is correlated with a reduction in the rate of homicides. The 1930s–1960s are a key period in the evolution of interpersonal violence. It coincides with the emergence of a welfare state (and increasing social expenditure), declining poverty rates, improvements in health and education, and an increase in suffrage.
Gathering narratives: Athletes’ experiences preparing for the Tokyo summer olympic games during a global pandemic

Abstract The COVID-19 pandemic, and the Tokyo Olympic Games postponement, has created unprecedented challenges for Olympic level athletes. Given the adversity athletes have faced since the World Health Organization (WHO) declared COVID-19 a global pandemic, the construct of psychological resilience is a useful framework for understanding athlete experiences during this time, and is conceptualized by Fletcher and Sarkar as an individual’s ability to protect against the negative effect of stressors. The purpose of this research was to explore the experiences of Canadian athletes preparing for the Tokyo summer Olympic Games during the COVID-19 global pandemic. Interviews were conducted with 20 Canadian athletes across individual and team sports. The participants spoke of the multiple ways they were taking care of themselves and developing resilience throughout the pandemic, highlighting the complexity involved with managing an adversity. Four narratives illuminate the athletes’ experiences: the critical role of context, the essential nature of social support, the importance of being more than an athlete, and the relevance of learning to reflect on one’s life. For these athletes, factors such as Olympic qualification, stage of their career, physical and mental health, and access to resources influenced their experience of the pandemic, demonstrating the importance of both individual and environmental factors when exploring resilience. Importantly, the athletes did not manage this adversity on their own, but received strong support. Therefore, sport psychology consultants can assist an athlete’s development of resilience by providing expertise and taking into account an athlete’s personal context. Lay summary: Twenty athletes preparing for the Tokyo Olympic Games during the COVID-19 pandemic were interviewed and four narratives are presented. All athletes were experiencing the pandemic differently based on their personal circumstances and were managing the adversity with social support, reflection, and pursuits beyond sport. APPLIED IMPLICATIONS Develop resources for coaches, athletes, and sport psychology practitioners to become competent in understanding and developing a high-performance sport environment that is both challenging and supportive Recognize the importance of social support in learning how to effectively reflect and develop pursuits outside of high-performance sport Understand and develop resilience, in a way that promotes, rather than diminishes, mental health
Effectiveness of Positive Psychotherapy on Depression and Alexithymia in Women Applying for a Divorce

Background The new therapeutic approach of positive psychotherapy has successfully treated severe mental disorders such as depression and mood disorders. However, existing research has not sufficiently measured the usefulness of this treatment in reducing depression and alexithymia. Objectives This study thus examined the effectiveness of positive psychotherapy in reducing these two conditions in a specific population: Iranian women applying for the divorce. Methods A total of 40 participants aged 20-40 with a high score in the Beck Depression Inventory and Toronto Alexithymia Questionnaire were recruited from women referred to a psychology clinic for divorce-related problems. The pretest, posttest, and follow-up were conducted with all participants, who were randomly placed in two groups: the experimental and control groups, which each consisted of 20 people. We provided eight positive psychotherapy sessions for only the experimental group. Results After MANCOVA was conducted, the results showed that positive psychotherapy significantly decreased alexithymia and depression in the test population.
Determinants of Investment Decisions in the Capital Market During the COVID-19 Pandemic

Research aims: This study aims to determine the effect of herding behavior, accounting information, and information technology on investment decisions through investment interest during the COVID-19 pandemic.Design/Methodology/Approach: Using the purposive sampling method, this study used a sample of investors who had just invested in the Indonesian capital market during the COVID-19 pandemic. This quantitative study employed primary data based on questionnaires distributed to respondents via the internet. Respondents in this study were 241 investors. Hypothesis testing in this study utilized SEM-PLS analysis through the SMART PLS 3.0 application.Research findings: The results showed that herding behavior did not affect investment decisions through investment interest in the capital market during the COVID-19 pandemic. Meanwhile, accounting information and technology information influenced investment decisions through investment interest in the capital market during the COVID-19 pandemic.Theoretical contribution/Originality: The study results contribute to the literature (body of knowledge), especially as additional discussion toward theory and literature related to herding behavior, accounting information, and information technology on investors decisions through investment interest to invest in the capital market, which is still very limited.
b-Generalized derivations act as a multipliers on prime rings

Abstract Let R be a prime ring of characteristic different from 2, U be its Utumi quotient ring with the extended centroid C and be a non-central multilinear polynomial over C. Suppose that F, G and H are b-generalized derivations on R such that for all then we describe all possible forms of F, G and H.
Identifying Problematic Gamblers using Multiclass and Two-stage Binary Neural Network Approaches

Responsible gaming has gained traction in recent years due to the harmful nature of compulsive online gambling and the increased awareness on the unfavourable consequences arising from this type of gambling. In Malta, legislation passed in 2018 places the onus of responsibility on online gaming companies has made studying this problem even more important. The focus of this research paper is to apply multistage and twostage artificial neural networks (ANN), and two-stage Bayesian neural networks (BNN), to the responsible gaming problem by training models that can predict the gambling-risk of a player as a multiclass classification problem. The models are trained using data from gambling session histories provided by a gaming company based in Malta. These models will then be compared using different performance metrics. It is shown that, while all approaches considered have their strengths, multiclass artificial neural networks perform best in terms of overall accuracy while the two-stage Bayesian neural network model performs best in classifying the most important class, the one where the players have a high risk of becoming problematic gamblers, and also second best at classifying the medium risk class.
Cross-Domain Knowledge Graph Chiasmal Embedding for Multi-Domain Item-Item Recommendation

Recommender system can provide users with the required information accurately and efficiently, playing a very important role in improving users’ life experience. Although knowledge graph-based recommender system can solve the sparsity and cold start problems faced by traditional recommender system, it cannot handle the cross-domain cold start problem and cannot provide multi-domain recommendations. Therefore, this paper focuses on multi-domain item-item (I2I) recommendation based on cross-domain knowledge graph embedding by analyzing the association between items of the same domain and the interaction between items of diverse domains with the aid of knowledge graph that contains rich information. First, a cross-domain knowledge graph chiasmal embedding approach is proposed to efficiently interact all items in multiple domains. To help achieve both homo-domain embedding and hetero-domain embedding of items, a binding rule is put forward. Second, a multi-domain I2I recommendation method is presented to efficiently recommend items in multiple domains, which is a recommendation method based on link prediction of knowledge graph. Finally, the proposed methods are compared and analyzed with some benchmark methods using two datasets. The experimental results show that the proposed methods achieve better link prediction results and multi-domain recommendation results.