Miracle-dz/UniFAR-FTUs huggingface dataset:
The pathobiology of select adolescent young adult lymphomas

Lymphoid cancers are among the most frequent cancers diagnosed in adolescents and young adults (AYA), ranging from approximately 30%–35% of cancer diagnoses in adolescent patients (age 10–19) to approximately 10% in patients aged 30–39 years. Moreover, the specific distribution of lymphoid cancer types varies by age with substantial shifts in the subtype distributions between pediatric, AYA, adult, and older adult patients. Currently, biology studies specific to AYA lymphomas are rare and therefore insight into age‐related pathogenesis is incomplete. This review focuses on the paradigmatic epidemiology and pathogenesis of select lymphomas, occurring in the AYA patient population. With the example of posttransplant lymphoproliferative disorders, nodular lymphocyte‐predominant Hodgkin lymphoma, follicular lymphoma (incl. pediatric‐type follicular lymphoma), and mediastinal lymphomas (incl. classic Hodgkin lymphoma, primary mediastinal large B cell lymphoma and mediastinal gray zone lymphoma), we here illustrate the current state‐of‐the‐art in lymphoma classification, recent molecular insights including genomics, and translational opportunities. To improve outcome and quality of life, international collaboration in consortia dedicated to AYA lymphoma is needed to overcome challenges related to siloed biospecimens and data collections as well as to develop studies designed specifically for this unique population.
Volatiles in glasses from the HSDP2 drill core

H2O, CO2, S, Cl, and F concentrations are reported for 556 glasses from the submarine section of the 1999 phase of HSDP drilling in Hilo, Hawaii, providing a high‐resolution record of magmatic volatiles over ∼200 kyr of a Hawaiian volcano's lifetime. Glasses range from undegassed to having lost significant volatiles at near‐atmospheric pressure. Nearly all hyaloclastite glasses are degassed, compatible with formation from subaerial lavas that fragmented on entering the ocean and were transported by gravity flows down the volcano flank. Most pillows are undegassed, indicating submarine eruption. The shallowest pillows and most massive lavas are degassed, suggesting formation by subaerial flows that penetrated the shoreline and flowed some distance under water. Some pillow rim glasses have H2O and S contents indicating degassing but elevated CO2 contents that correlate with depth in the core; these tend to be more fractionated and could have formed by mixing of degassed, fractionated magmas with undegassed magmas during magma chamber overturn or by resorption of rising CO2‐rich bubbles by degassed magmas. Intrusive glasses are undegassed and have CO2 contents similar to adjacent pillows, indicating intrusion shallow in the volcanic edifice. Cl correlates weakly with H2O and S, suggesting loss during low‐pressure degassing, although most samples appear contaminated by seawater‐derived components. F behaves as an involatile incompatible element. Fractionation trends were modeled using MELTS. Degassed glasses require fractionation at p ≈ 5–10 bars. Undegassed low‐SiO2 glasses require fractionation at p ≈ 50 bars. Undegassed and partially degassed high‐SiO2 glasses can be modeled by coupled crystallization and degassing. Eruption depths of undegassed pillows can be calculated from their volatile contents assuming vapor saturation. The amount of subsidence can be determined from the difference between this depth and the sample's depth in the core. Assuming subsidence at 2.5 mm/y, the amount of subsidence suggests ages of ∼500 ka for samples from the lower 750 m of the core, consistent with radiometric ages. H2O contents of undegassed low‐SiO2 HSDP2 glasses are systematically higher than those of high‐SiO2 glasses, and their H2O/K2O and H2O/Ce ratios are higher than typical tholeiitic pillow rim glasses from Hawaiian volcanoes.
Equation of state of liquid Fe‐10 wt % S: Implications for the metallic cores of planetary bodies

[1] The equation of state (EOS) of molten Fe-10 wt % S was investigated by means of static high-pressure density measurements using a newly developed variation of the sink/float technique. The method involves the use of tailored density composite spheres made of Pt or WC cores and an Al2O3 (ruby/sapphire) mantle as bracketing markers for comparative density measurements of liquid Fe-10 wt % S at pressures (P) up to 20 GPa and at temperatures (T) up to 2123 K. The results of isothermal compression data confirm the validity of extrapolating to 20 GPa an EOS for pressures up to 6 GPa obtained earlier by Sanloup et al. [2000] using an X-ray absorption technique. The analysis of new data obtained in the 1773–2123 K interval up to 20 GPa resulted in new EOS parameters and also revealed the need for a well-determined melt density value at 1 atm. Application of our results to the identification of composition of liquid metallic cores of Ganymede, Io, and Mars showed Fe-10 wt % S to be a possible candidate. We used different EOS formulations to extrapolate our results to the P-T conditions of the Earth's interior. For temperatures between 4773 K at the core-mantle boundary and 5973 K at the inner core boundary the extrapolation made using the Vinet EOS resulted in density values closest to the density of the core suggested by the preliminary reference Earth model.
Is There Any Evidence of Mega-Lake Manly in the Eastern Mojave Desert during Oxygen Isotope Stage 5e/6? A Comment on Hooke, R. L. (1999). Lake Manly(?) Shorelines in the Eastern Mojave Desert, California, Quaternary Research 52, 328–336

onosits Hooke(1999) rekindled the hypothesis that a large lake (m Lake Manly) filled Death Valley and the adjoining Silver/So Lake during pluvial periods (e.g., Hale, 1985). Like Hooke, also have been investigating lake deposits, strandline feat and Quaternary tectonics in the Death Valley, Silurian Val and the Silver/Soda Lake areas for more than a decade Wells et al., 1989; Brownet al., 1990; Enzel, 1990; Anderso and Wells, 1996; Knottet al., 1996, 1999; Enzel and Well 1997; Knott, 1997, 1998; Anderson, 1998, 1999). On the b of drill cores, detailed geologic mapping, survey data, 14C dates, luminescence dating, soil descriptions, and tephrochronol we strongly disagree with both Hooke’s large-lake hypothe and his tectonic reconstruction. We believe there are suffic data to conclude that, contrary to Hooke’s claims, (1) the plu features and deposits at Silver Lake and Salt Spring Hills resent lakes formed in different terminal playas between 30 and 9000 yr ago and thus are not coeval with the ∼186,000– 120,000 yr B.P. Blackwelder strandline of Death Valley (We et al., 1989; Brownet al., 1990; Anderson and Wells, 1997; K et al., 1998), (2) the Blackwelder strandline deposits are on footwall block of the Black Mountains and thus have either be uplifted or, at the very least, unchanged relative to the regio the south; and (3) the Salt Spring Hills and Silver Lake shoreli are not tilted (Wellset al., 1989; Brownet al., 1990; Anderson, 1999), suggesting that they have only minimally been affec if at all, by tectonic activity. Below, we review both the da presented by Hooke in support of his hypothesis and the from studies that preceded Hooke (1999), data that we a contradict Hooke’s findings. Hooke (1999) could have addressed the problem (reconst ing the mega-lake or its deformed shorelines) from at least logical perspectives: if he had tectonic data (rates of rela movement from Shoreline Butte to Mesquite Hills) he cou have tried to correlate the shorelines using the elevations rates of movement; or, if he had age control on the shoreli he could have reconstructed the rates of tectonic movemen stead, Hooke—with neither age control on the shorelines no dependent control on the tectonic activity—treated all shorel to be of similar age, correlated them over a distance of ∼200 km, and proposed a major tectonic warping in the Mojave Dese
Synthesis ofzce Studies–Kurile Islands Earthquake of October 13, 1963

Normal mode solutions for a spherical earth model are superposed to obtain realistic synthetic surface waves for various force systems. The calculation of excitation functions is greatly facilitated by the variational technique. The effects of attenuation and instrument response are included in the synthesis. The synthesized seismograms are compared with the actual seismograms for wave form, amplitude, radiation pattern, and phase to obtain various source parameters such as force geometry, source-time function, seismic moment, source dimension, and rupture velocity. The application is made to the Kurile Island earthquake of October 13, 1963 (M = 8.3). The comparison is made for Love waves G4 and Rayleigh waves R4 for a period range 100 to 400 sec. It is found that a reverse dip-slip fault with a dip angle of 22° and a dip direction of N47°W can explain the observation reasonably well. Other parameters determined are as follows: seismic moment, 7.5×1028 dyne-cm; source-time function, step function; fault length, 200 to 300 km; rupture velocity, 2.7 to 4.5 km/sec in the direction N43°E.
Mineralogical-petrographical features, geochemical characteristics, and S isotope variability of Pb-Zn deposits in the Sakarya fragment of the Biga Peninsula (NW Türkiye)

: The Biga Peninsula in northwestern Anatolia, a part of the Alpine-Himalayan orogenic belt, has a complex geology that was formed following the closure of the northern branch of the Neotethys. Intense volcanism and plutonism in the area from the Eocene to the Middle Miocene period caused several Pb-Zn-Cu±Ag±Au deposits to form. The geometry of the mineralizations is largely made up of polymetallic veins, manto-chimneys, and irregular replacement bodies. Ore-bearing and host rocks in the mineralization zones and the wall rocks outside the mineralization zones were compiled in this study. The most common minerals in the skarn zones are garnet, pyroxene, amphibole, epidote, chlorite, quartz, and calcite, while quartz, calcite, and sericite are formed in the hydrothermal alteration zones. Based on the geochemical analyses, the granitoidic rocks are granodiorite, whereas the volcanic rocks are dacite, andesite, trachyandesite
Impact of Cycling Intensity on Cycle-run Transition in Female Triathletes

PURPOSE:Â The purpose of the study was to determine the impact of intensity during the final km of a cycling bout on subsequent run and overall cycle-run (CR) performance. Â A secondary aim of the study was to examine how manipulations in cycling power affect cycle-run performance in female triathletes exclusively. METHODS:Â Nine well-trained female triathletes participated in the study. Â The triathletes completed two CR sessions (20 km cycle, 5 km run). Â The intensity of the first 19 km of cycling was equivalent to peak power at 70% of peak oxygen consumption (O 2 peak) and the final 1 km varied between power achieved at 95% of O 2 peak (high intensity, HI) and power achieved at 50% of O 2 peak (low intensity, LI). Â The 5 km run was completed as fast as possible. RESULTS:Â Mean blood lactate concentration [La - ] was significantly higher during the run following the cycling bout ending with a HI rather than a LI (11.5 Â± 0.64 mmol/L vs. 9.3 Â± 0.72 mmol/L). Â Run performance was not significantly different between HI and LI (24:54 Â± 02:53 min vs. 00:24:36 Â± 00:03:17 min). Â As well, no significant differences were found between overall CR sessions (01:23:23 h Â± 00:05:47 min vs. 01:23:50 h Â± 00:07:01 min). CONCLUSION:Â Despite increases in [La - ], cycling intensity during the final stages of a 20 km cycling bout does not impact run or CR performance in well-trained female triathletes.
Circulation on the western South Atlantic continental shelf: 2. Spring and autumn realistic simulations

[1] Buoyancy-driven currents are here investigated in a complex scenario, where two river plumes (the La Plata River and the Patos Lagoon plumes) occur in the vicinity of two opposing western boundary currents (the Malvinas and the Brazil currents). The study addresses the contrasting scenarios found during the austral spring and fall seasons, due to variations in river discharge, in wind stress, and in the boundary current transport. The winds blow preferably from the northeast during the spring and from the southwest during the fall. The Brazil Current transport is stronger during the spring, when the Brazil-Malvinas Confluence is displaced southward, and weaker during the fall when the confluence moves northward. The study is conducted as a series of numerical simulations which consider the river discharges, the tides, variable wind stress, and thermohaline fields which are realistic in terms of the Brazil-Malvinas Confluence. Our discussion focuses on the riverine water distribution in each season. The austral fall scenario shows coastally trapped plumes, and the spring scenario shows significant offshore removal, but our fall plumes are not too elongated and narrow as other authors found in the presence of constant winds, no tides, and no boundary currents, and our spring offshore removal is not as strong as found by others.
Geomorphology of the Lake Tana basin, Ethiopia

The geomorphological map of the Lake Tana basin (15,077 km2, Nile basin, Ethiopia) presented in this paper was prepared from fieldwork data, maps and satellite data that were processed with a geographic information system (GIS). It contains four major components: (i) hydrography, (ii) morphology and morphometry, (iii) materials and (iv) processes at a scale of 1:500,000. The geomorphological setting of the basin consists of lavas that erupted from fissures or (shield) volcanoes during the Tertiary and Quaternary eras, were uplifted and eroded primarily by water. Lake Tana emerged through a combination of a lava barrier blocking the Blue Nile to the south and by epirogenetic subsidence. When the lake reached its maximum extent, extensive lacustrine plain (e.g. Fogera and Dembia plains) were created, river valleys and basins were filled with sediment and higher lying topography was eroded. Today, the lake plays a lesser role in landscape formation because of a decreased extent (3041 km2) compared to the ancient maximum (6514 km2). Dominant processes today are fluvial and subaerial. Recent (1886–2010) changes in the lake coastline are small with the exception of the delta formed by Gilgel Abay, which has increased disproportionally over the last 15 years. This indicates a large input of sediment which is mainly due to rivers flowing through Quaternary lavas. The recent sediment input increase is most probably related to human induced land-use changes.
Discovering research value in the Campo del Cielo, Argentina, meteorite craters

The Campo del Cielo meteorite crater field in Argentina contains at least 20 small meteorite craters, but a recent review of the field data and a remote sensing study suggest that there may be more. The fall occurred ∼4000 years ago into a uniform loessy soil, and the craters are well enough preserved so that some of their parameters of impact can be determined after excavation. The craters were formed by multi-ton fragments of a type IA meteoroid with abundant silicate inclusions. Relative to the horizontal, the angle of infall was ∼9°. Reflecting the low angle of infall, the crater field is elongated with apparent dimensions of 3 × 18.5 km. The largest craters are near the center of this ellipse. This suggests that when the parent meteoroid broke apart, the resulting fragments diverged from the original trajectory in inverse relation to their masses and did not undergo size sorting due to atmospheric deceleration. The major axis of the crater field as we know it extends along N63°E, but the azimuths of infall determined by excavation of Craters 9 and 10 are N83.5°E and N75.5°E, respectively. This suggests that the major axis of the crater field is not yet well determined. The three or four largest craters appear to have been formed by impacts that disrupted the projectiles, scattering fragments around the outsides of the craters and leaving no large masses within them; these are relatively symmetrical in shape. Other craters are elongated features with multi-ton masses preserved within them and no fragmentation products outside. There are two ways in which field research on the Campo del Cielo crater field is found to be useful. (1) Studies exist that have been used to interpret impact craters on planetary surfaces other than the Earth. This occurrence of a swarm of projectiles impacting at known angles and similar velocities into a uniform target material provides an excellent field site at which to test the applicability of those studies. (2) Individual craters at Campo del Cielo can yield the masses of the projectiles that formed them and their velocities, angles and azimuths of impact. From these data, there is a possibility to estimate parameters for the parent meteoroid at entry and, thus, learn enough about its orbit to judge whether or not it was compatible with an asteroidal origin. Preliminary indications are that it was. Campo del Cielo is a IA iron meteorite and Sikhote-Alin, an observed fall, is a IIB iron meteorite in Wasson's classification. The Sterlitamak iron, also an observed fall, is a medium octahedrite in the Prior-Hey classification. It would be interesting to compare their orbital parameters.
Grammatical Gender and Politics: A Comparison of French and English in Political Discourse

Grammatical gender systems are prevalent across many languages, and when comparing French and English the existence of this system becomes a strong distinction. There have been studies that attribute assigned grammatical gender with the ability to influence conceptualization (attributing gender attributes) of all nouns, thus affecting people's thoughts on a grand scale. We hypothesized that due to the influence of a grammatical gender system, French political discourse would have a large difference between the number of masculine and feminine nouns used. Specifically, we predicted there would be a larger ratio of feminine to masculine nouns in French political discourse than in non-political discourse when compared to English discourse. Through linguistic analysis of gendered nouns in French political writing, we found that there is a clear difference between the number of feminine versus masculine nouns, signaling a preference for a more “effeminate” language. This preference can be attributed towards the utilization of the conceptualization of nouns in swaying public opinion. We examined the ratio of complex words (two syllables or more) to the total number of words across both English and French political and non-political writing. When comparing these four categories, we found a significant increase in complexity from non-political to political writing in English, all of which were more complex than French writing. This suggests that, due to a lack of a grammatical gender system, English resorts to grand but vague language that hinders delivery and clarity in political discourse.
Impact of Customer Accounting on the Operational Performance of Vietnamese Enterprises

The paper aims to evaluate the impact of the use of customer accounting information including Customers Profitability Analysis (CPA), Lifetime Customers Profitability Analysis (LCPA), and Valuation of Customers Assets (VCA) on the Operational Performance of enterprises (OPE). The study was conducted based on surveys from 315 subjects. They included directors, unit managers, and accountants in Vietnamese enterprises. By multivariate regression analysis from SPSS 20 software, the results show that the use of customer accounting information, analysis of customer profitability, and customer assets valuation are vital aspects of customer accounting that impact business performance. The level of use of CPA has the most substantial effect on business performance (coefficient is 0.250), next is the impact of using VCA (coefficient is 0.246). The study also shows that the age and size of enterprises have a positive impact on performance. However, this study did not determine the effect of LCPA on business performance. The research results are the basis for proposing solutions to improve the performance of enterprises in Vietnam from the use of customer accounting information.
Macroscopic description and histopathological characterization of lesions observed on fish farmed within the Saint-Louis region of Senegal

Fish farming, one of the priority sectors in Senegal, is well established in the Saint-Louis region, which offers a high potential, with more than 50% of farms in activity and dispose of a well-supplied hydrographic network and support services (executive agencies and university). However, this development is correlated with a variety of health problems observed in the most cultured fish in Senegal (tilapia and catfish). The objective of this study is to describe the clinical cases and lesions observed in tilapia ( Oreochromis niloticus ) and catfish ( Clarias gariepinus ), reared in fish farms in the Saint-Louis region. The study started with surveys followed by the description of clinical signs and macroscopic lesions observed on sick or freshly dead fish and then by bacteriological and histopathological examinations. Results from the investigations have highlighted, firstly, the risks of chemical or microbiological contamination related to the proximity of habitations to fish farms (environmental contamination), and secondly, the fluctuations of physico-chemical parameters and the degradation of water quality, feed quality and its storage conditions. The results showed that clinical cases are associated with lesions either localized on different parts of the body (fins, gills, eyes), or generalized to external and internal organs. Cases of malformations and swollen masses were also noted. Bacteriological analysis revealed the presence of Aeromonas hydrophila , in co-infection with Vibrio sp. Histology confirmed multiple necrotic, hemorrhagic and cystic lesions on skin and in other organs. The observed clinical cases are associated with the poor conditions of fish farming and of the local environment in the study area.