Miracle-dz/UniFAR-FTUs huggingface dataset:
A New Strategy for Somatotype Assessment Using Bioimpedance Analysis: Stratification According to Sex

Body composition assessment is a relevant element in the biomedical field, in research and daily practice in the medical and nutritional fields, and in the management of athletes. This paper aimed to operate in an Italian sample investigating the possibility of predicting the somatotype from bioimpedance analysis and comparing the predicted results with those obtained from anthropometric measurements. This observational study was conducted with retrospective data collected from 2827 subjects. The somatotype of each subject was calculated both with the Heath–Carter method and by a multiple regression model based on bioimpedance and anthropometric parameters. Somatotypes (endomorph, mesomorph, and ectomorph) were predicted with a high goodness of fit (R2 adjusted > 0.80). Two different somatocharts were obtained from anthropometric measures and bioimpedance parameters and subsequentially compared. Bland–Altman plots showed acceptable accuracy. This study could be a first step in developing a new approach that allows the detection of a subject’s somatotype via bioimpedance analysis, stratified according to sex, with a time-saving and more standardized procedure. It would allow, for example, during the COVID-19 pandemic, to minimize operator–patient contact in having measurements.
A generalized single‐index linear threshold model for identifying treatment‐sensitive subsets based on multiple covariates and longitudinal measurements

Identification of a subset of patients who may be sensitive to a specific treatment is an important step towards personalized medicine. We consider the case where the effect of a treatment is assessed by longitudinal measurements, which may be continuous or categorical, such as quality of life scores assessed over the duration of a clinical trial. We assume that multiple baseline covariates, such as age and expression levels of genes, are available, and propose a generalized single‐index linear threshold model to identify the treatment‐sensitive subset and assess the treatment‐by‐subset interaction after combining these covariates. Because the model involves an indicator function with unknown parameters, conventional procedures are difficult to apply for inferences of the parameters in the model. We define smoothed generalized estimating equations and propose an inference procedure based on these equations with an efficient spectral algorithm to find their solutions. The proposed procedure is evaluated through simulation studies and an application to the analysis of data from a randomized clinical trial in advanced pancreatic cancer.
Virtual Screening and Quantitative Structure–Activity Relationship of Moringa oleifera with Melanoma Antigen A (MAGE-A) Genes against the Therapeutics of Non-Small Cell Lung Cancers (NSCLCs)

Simple Summary A variety of phytochemicals found in Moringa oleifera have been found to be biomedically active. MAGE-A variants are expressed in most carcinoma cells, and the current study aims at the computational discovery of phytochemicals in treating NSCLC via MAGE-A targeting. Abstract In the last decade, there have been significant advancements in the treatment of non-small cell lung cancer, including remarkable gains in detection, diagnosis, and therapy. The emergence of molecular targeted therapies, immunotherapeutic inhibitors, and antiangiogenesis medicines has largely fueled improvements in combination therapy and systemic treatments, all of which have dramatically ameliorated patient outcomes. The Moringa oleifera bioactive compounds have been effective in the suppression of cancers, making them the therapeutic agents of choice for the current investigation to treat MAGE-A presented in NSCLC. The ligand entrants were screened for their pharmacological properties, and 2,2-diphenyl-1,3-benzodioxole was stipulated as the lead candidate. 2,2-Diphenyl-1,3-benzodioxole exhibited better pharmacological properties and superior binding with branched-chain amino acids, making it an ideal candidate to address MAGE-A. The study concluded that addressing MAGE-A to impede their activity and antigenicity can be exploited as immunotarget(s).
Optical Physics of Microcavity Surface Emitting Lasers

Abstract : This dissertation consists of an in-depth theoretical analysis of the optical impact of transverse index confinement on the lasing modes of microcavity surface emitting lasers. Two different variational techniques were employed to calculate the relevant optical laser parameters: (1) modal resonance, field profile, (2) confinement factor, and (3) threshold gain. Through a semianalytic field analysis, two new confinement related effects were discovered: (1) a polarization dependent change in mirror reflectance with aperture radius, and (2) a mode dependent blueshift. Through a numerical field analysis, the physical mechanisms governing diffraction were ascertained. These are: (1) the transverse confinement of the optical mode, the degree of tilt of the mode propagation vector away from normal to the mirror surfaces, and (2) the density of parasitic modes in the spectral vicinity of the lasing mode. Based on these results, a new semianalytic technique was derived for estimating diffraction loss via rigorous coupling to the parasitic modes. Finally, this model was combined with a gain model and a new mode density model to compute spontaneous emission rate, light verses current, threshold current, and spontaneous emission factors for a low threshold oxide-apertured device.
Time series analysis of the suicide attempts assisted by firefighters from 2017 to 2021 in São Paulo, Brazil.

OBJECTIVE This study aimed to analyze the time trends of suicide attempts assisted by the Fire Department of the Military Police of the State of São Paulo (Corpo de Bombeiros da Polícia Militar do Estado de São Paulo - CBPMESP) from 2017 to 2021, between sexes. METHODS This is an ecological study of 11,435 suicide attempts assisted by CBPMESP calls from January 2017 to December 2021. Three seasonal auto-regressive integrated moving average with exogenous (SARIMAX) models were adjusted considering total population, only men, and only women. RESULTS The total occurrences of suicide attempts were stationary in the prepandemic period but had an increased growth pattern after the pandemic began. This trend was higher among men, due to (1) lower assistance of suicide attempts during early pandemic than in the prepandemic period and (2) significant increased assistance after the beginning of vaccination against COVID-19, followed by a decrease, but with a tendency to increase, in the long-term pandemic. CONCLUSION Our results indicate a growth in the long-term suicide attempts during COVID-19. The beginning of vaccination was not considered significant in the reduction of CBPMESP attendances. These results corroborate the need for a multisectoral national suicide prevention strategy to mitigate the effects of the pandemic on mental health in the State of São Paulo.
First Observations of a Foreshock Bubble at Earth: Implications for Magnetospheric Activity and Energetic Particle Acceleration

Earth? s foreshock, which is the quasi-parallel region upstream of the bow shock, is a unique plasma region capable of generating several kinds of large-scale phenomena, each of which can impact the magnetosphere resulting in global effects. Interestingly, such phenomena have also been observed at planetary foreshocks throughout our solar system. Recently, a new type of foreshock phenomena has been predicted: foreshock bubbles, which are large-scale disruptions of both the foreshock and incident solar wind plasmas that can result in global magnetospheric disturbances. Here we present unprecedented, multi-point observations of foreshock bubbles at Earth using a combination of spacecraft and ground observations primarily from the Time History of Events and Macroscale Interactions during Substorms (THEMIS) mission, and we include detailed analysis of the events? global effects on the magnetosphere and the energetic ions and electrons accelerated by them, potentially by a combination of first and second order Fermi and shock drift acceleration processes. This new phenomena should play a role in energetic particle acceleration at collisionless, quasi-parallel shocks throughout the Universe.
Does the Type of Anaerobic Test Matter? A Comparison between the Anaerobic Intermittent Kick Test and Wingate Anaerobic Test in Taekwondo Athletes

The specificity of training as well as the specificity of monitoring the training process are believed to be fundamental principles to efficiently plan and carry out the preparation and performance development of athletes. The Anaerobic Intermittent Kick Test (TAIKT) is a sport-specific field test used to specifically evaluate the anaerobic profile of Taekwondo athletes. The aim of this study was to verify whether TAIKT and the ‘gold standard’ Wingate Anaerobic test (WAnT) were both efficient means to optimally determine the anaerobic power and anaerobic capacity of Greek Taekwondo athletes at a middle-high technical level. Fifteen athletes, 10 females and 5 males (mean age 23.4 ± 4.14 years), underwent the two anaerobic tests (TAIKT and WAnT). The peak of power, the anaerobic capacity, and the peak of blood lactate (BL) were recorded. The two tests showed a moderate correlation with the r value ranging between 0.353 and 0.428, if applied to a sample of middle-high technical level athletes. Regarding the peak of BL, data indicated 40% concordance between the two tests with a coefficient of variation of 12%. Consequently, the two tests were correlated even if not interchangeable due to the different type of exercise required in these assessments. In conclusion, to assess the anaerobic performances and physiological characteristics of Taekwondo athletes, independently of their technical level, the WAnT resulted suitable, while to better assess the functional performance and specific demands of Taekwondo, the TAIKT is more indicated.
Internal or External Word-of-Mouth (WOM), Why Do Patients Choose Doctors on Online Medical Services (OMSs) Single Platform in China?

(1) Background: Word-of-mouth (WOM) can influence patients’ choice of doctors in online medical services (OMSs). Previous studies have explored the relationship between internal WOM in online healthcare communities (OHCs) and patients’ choice of doctors. There is a lack of research on external WOM and position ranking in OMSs. (2) Methods: We develop an empirical model based on the data of 4435 doctors from a leading online healthcare community in China. We discuss the influence of internal and external WOM on patients’ choice of doctors in OMSs, exploring the interaction between internal and external WOM and the moderation of doctor position ranking. (3) Results: Both internal and external WOM had a positive impact on patients’ choice of doctors; there was a significant positive interaction between internal and third-party generated WOM, but the interaction between internal and relative-generated WOM, and the interaction between internal and doctor-generated WOM were both nonsignificant. The position ranking of doctors significantly enhanced the impact of internal WOM, whereas it weakened the impact of doctor recommendations on patients’ choice of doctors. (4) The results emphasize the importance of the research on external WOM in OMSs, and suggest that the moderation of internal WOM may be related to the credibility and accessibility of external WOM, and the impact of doctor position ranking can be explained by information search costs.
Electro-Design of Bimetallic PdTe Electrocatalyst for Ethanol Oxidation: Combined Experimental Approach and Ab Initio Density Functional Theory (DFT)—Based Study

An alternative electrosynthesis of PdTe, using the electrochemical atomic layer deposition (E-ALD) method, is reported. The cyclic voltammetry technique was used to analyze Au substrate in copper (Cu2+), and a tellurous (Te4+) solution was used to identify UPDs and set the E-ALD cycle program. Results obtained using atomic force microscopy (AFM) and scanning electron microscopy (SEM) techniques reveal the nanometer-sized flat morphology of the systems, indicating the epitaxial characteristics of Pd and PdTe nanofilms. The effect of the Pd:Te ratio on the crystalline structure, electronic properties, and magnetic properties was investigated using a combination of density functional theory (DFT) and X-ray diffraction techniques. Te-containing electrocatalysts showed improved peak current response and negative onset potential toward ethanol oxidation (5 mA; −0.49 V) than Pd (2.0 mA; −0.3 V). Moreover, DFT ab initio calculation results obtained when the effect of Te content on oxygen adsorption was studied revealed that the d-band center shifted relative to the Fermi level: −1.83 eV, −1.98 eV, and −2.14 eV for Pd, Pd3Te, and Pd3Te2, respectively. The results signify the weakening of the CO-like species and the improvement in the PdTe catalytic activity. Thus, the electronic and geometric effects are the descriptors of Pd3Te2 activity. The results suggest that Pd2Te2 is a potential candidate electrocatalyst that can be used for the fabrication of ethanol fuel cells.
On Why Intermediate-Mass Stars Become Giants after the Exhaustion of Hydrogen in Their Cores

Several numerical experiments are performed in an attempt to isolate those factors which do, or do not, play a primary role in the expansion to giant dimensions of intermediate-mass stars after they have exhausted hydrogen in their cores. Experiment characteristics are (A) opacity k=0.2 (1+X) cm 2 g -1 ; (B) k=0.2 (1+0.71) cm 2 g -1 ; (C) k=2 cm 2 g -1 , molecular weight constant at μ=0.61; (D) k=2 cm 2 g -1 , μ realistically variable; (E) k=2 cm 2 g -1 , μ realistic, convection forced when temperature T<1.1×10 6 K; (F) k and μ realistic, normal criterion for convection
Volatile Compounds and Antioxidant and Antifungal Activity of Bud and Needle Extracts from Three Populations of Pinus mugo Turra Growing in Romania

Pinus mugo Turra is a shrub-like conifer with multiple healing properties. P. mugo extracts are rich in active ingredients such as volatile compounds, tannin, higher alcohols, vitamins, and minerals. In this study, we identified and quantified the secondary metabolites from buds and needles of P. mugo harvested from three different mountain areas in Romania. The main volatile compounds contained in the extracts were analyzed by gas chromatography coupled with mass spectrometry, and the most significant were pinene, germacrene, limonene, and caryophyllene. The total polyphenol content (TPC) was in the range of 46.77 ± 0.3 and 77.99 ± 0.5 mg GAE/g and the total flavonoid content (TFC) 24.90 ± 0.1 and 54.78 ± 0.3 mg QE/g. The content of ascorbic acid ranged between 12.21 mg/100 g and 27.34 mg/100 g, concentrations that are recommended for natural sources of ascorbic acid. Moderate antimicrobial activity on yeasts and molds was not dependent on plant origin. By highlighting the rich content of active compounds, and moderate antioxidant and antifungal activity, this study is an argument for the beneficial use of P. mugo bud and needle extracts, regardless of the habitat of origin on the Romanian territory, in the fields of medicine and the food industry or in the implementation of eco-friendly practices.
Effect of Different Cover Crops on Suppression of the Weed Oxalis pes-caprae L., Soil Nutrient Availability, and the Performance of Table Olive Trees ‘Kalamon’ cv. in Crete, Greece

Winter cover crops are used in organic olive production to increase N-supply and yields, and to reduce weed competition. However, there is limited information on the effect of different cover crops on weed suppression, soil fertility and productivity of organic olive orchards. Here, we compared the relative effect of four contrasting cover crops established from (i) untreated vetch seed, (ii) vetch seed inoculated with a commercial Rhizobium seed inoculum, (iii) an untreated vetch/barley/pea seed mixture and (iv) untreated seed of Medicago polymorpha L. (a native legume species which establishes naturally in olive orchards in Crete) in a 35-year-old experimental table olive orchard. The use of a vetch/barley/pea mixture resulted in the greatest suppression of the dominant weed species Oxalis pes-caprae. Rhizobium inoculation of vetch seed resulted in significantly lower vetch establishment and significantly higher Oxalis suppression but had no significant effect on the root nodulation of vetch plants. There was no significant difference in fruit yield between cover crop treatments, but the fruit weight was significantly higher when cover crops were established from un-treated vetch seeds and the vetch/barley/pea seed mixture compared with the cover crops based on inoculated vetch or Medicago seed. However, although Medicago establishment was very low (<10 plants/m2), fruit yields were numerically 20% higher in the Medicago plots. These findings suggests that, overall, legume cover crops had no effect on fruit yields. This conclusion is supported by the results of the olive leaf analyses which detected no significant differences in nitrogen and other mineral macro- and micronutrient concentration between treatments, except for B (highest in olive leaves from Medicago and lowest in untreated vetch plots) and Mo (highest in olive leaves from Medicago and lowest in vetch/barley/pea mixture plots). Overall, our results suggest that the current recommendation to establish legume-based cover crops in organic olive orchards every year, may need to be revised and that establishing cover crops every 2–4 years may reduce costs without affecting olive fruit yields.
A novel intelligent mobile application using human-centered AR: A case study in orange inspection

O crescente interesse em tecnologias de Realidade Aumentada (RA) está aumentando devido ao seu uso recente por diversos setores produtivos da indústria. Também, por Indústria 4.0, um dos pilares é RA e inteligência artificial (IA) para apoiar colaboração homem-máquina. A IA centrada no ser humano é uma pesquisa emergente área com foco no fornecimento de soluções interativas para apoiar as atividades humanas. Este artigo apresenta um aplicativo móvel (App) inovador composto por um RA interface conectada a uma IA para auxiliar um usuário na tomada de decisão interativa em a inspeção laranja.
Model to Predict Oral Frailty Based on a Questionnaire: A Cross-Sectional Study

A statistical model to predict oral frailty based on information obtained from questionnaires might help to estimate its prevalence and clarify its determinants. In this study, we aimed to develop and validate a predictive model to assess oral frailty thorough a secondary data analysis of a previous cross-sectional study on oral frailty conducted on 843 patients aged ≥ 65 years. The data were split into training and testing sets (a 70/30 split) using random sampling. The training set was used to develop a multivariate stepwise logistic regression model. The model was evaluated on the testing set and its performance was assessed using a receiver operating characteristic (ROC) curve. The final model in the training set consisted of age, number of teeth present, difficulty eating tough foods compared with six months ago, and recent history of choking on tea or soup. The model showed good accuracy in the testing set, with an area of 0.860 (95% confidence interval: 0.806–0.915) under the ROC curve. These results suggested that the prediction model was useful in estimating the prevalence of oral frailty and identifying the associated factors.
Hubble Space Telescope Imaging of z ≥ 0.4 Quasar Host Galaxies Selected by Quasar Radio and Optical Properties

A sample of 16 quasars selected from the Large Bright Quasar Survey in the redshift range 0.4 < z < 0.5 has been imaged in the R band with the Planetary Camera on the WFPC2 instrument of the Hubble Space Telescope. The host galaxy magnitudes are mostly similar to or brighter than L*, and the host luminosity is positively correlated with the luminosity of the quasar nuclear component. There is no distinction in host galaxy magnitude between radio-loud and radio-quiet quasars, assuming they are all of the same galaxy type. Many of the host galaxies in the sample have small axial ratios, which may indicate that they are inclined disk systems. Alternatively, this elongated appearance may be due to bars or other distinctive morphological features which are visible while the bulk of the underlying lower surface brightness components of the host galaxy are not.
Physiological Responses of Lettuce (Lactuca sativa L.) to Soil Contamination with Pb

Contamination of agricultural soils with heavy metal leads to a decrease in the crop quality and yield, as well as increases in public health risks. In this study, we aimed to evaluate the impact of soil contamination with lead (Pb) on the growth, photosynthesis, respiration, and coupling between these physiological processes, as well as temporal dynamics of Pb uptake and accumulation by lettuce (Lactuca sativa L.) plants. For this 46-day pot experiment, Pb(NO3)2 was mixed with loamy Retisol soil with the rate of 0, 50, and 250 mg kg−1. No significant differences in plant biomass accumulation were found between plants grown on Pb-free and Pb-rich soil, but root-weight ratio, root-to-shoot weight ratio, and leaf area were lower, and the number of leaves and leaf weight per unit area were significantly higher in plants grown on soil contaminated with Pb than in their counterparts grown on Pb-free soil. The concentration of Pb in plant root and shoot followed the increase in soil Pb, with Pb content in the roots being higher than in the shoots. Soil Pb decreased chlorophyll content, net CO2 assimilation rate and photosynthetic light use efficiency, but caused an increase in the leaf respiration rate regardless of whether respiration was performed in the light or in darkness. Increased ratio of respiration to photosynthesis reflects the shift in the carbon balance of lettuce plants toward carbon losses under stress conditions of soil contamination with Pb.
Bail-in credibility: evidence from emerging markets

PurposeSome controversial cases of bail-in in the emerging countries have raised the question about whether for those countries to have in place a regulation for the bail-in is appropriate or not. To assess appropriateness, this paper investigates bail-in credibility among investors, as crucial condition for the credibility’s smooth implementation, by measuring the yield spread between bailinable and non-bailinable bonds.Design/methodology/approachThe authors compare the yield spread of banks located in emerging countries that have in place a framework for the bail-in to the comparable yield spread measured for banks located in emerging countries without such framework. The comparison permits to detect whether there is a significant difference between the two spreads, which would suggest that bail-in regulation has been deemed credible by market participants where enforced, or not, which in this case would signal a problem of credibility.FindingsThe authors' results point out a significantly higher yield spread for banks located in emerging countries that have adopted a framework for the bail-in of creditors. Bail-in regulation has, therefore, being deemed credible in the adopting emerging countries, thus ensuring a crucial condition for bail-in regulation's smooth application. The authors also point out bank size and country's gross domestic product (GDP) growth as crucial moderators of bail-in expectations of market participants that can guide the implementation of bail-in rules in emerging countries.Originality/valueThis paper contributes to the literature on the credibility of bail-in with a new perspective from the emerging countries.