Miracle-dz/UniFAR-FTUs huggingface dataset:
Soft-tissue characteristics of Class II division 2 malocclusion in North Indian adult population: A comparative study

Aims and Objectives: To evaluate and compare the soft-tissue characteristics associated with Angle′s Class-I normal occlusion and Angle′s Class-II division-2 malocclusion in North Indian adult population. Materials and Methods: Lateral cephalograms of 70 orthodontically untreated adult subjects, 40 were having normal occlusion (Group-A) with good facial profile (20 males - mean age 22.89 years and 20 females - mean age 21.27 years) and 30 subjects with Angle′s Class-II division-2 malocclusion (Group-B) (15 males - mean age 22.50 years and 15 females - mean age 20.25 years) were analyzed. All the cephalograms were taken in natural head position, traced manually and 16 linear and 6 angular soft tissue parameters were measured which were derived from the Steiner, Ricketts, Burstone and Holdaway soft-tissue analyses. All the values were compared using Student′s t-test with a level of significance at P < 0·05. Results: Group-B males had significantly higher mean values for lip-line, soft-tissue thickness at labialis inferior (P < 0.05), and total facial contour angle (P < 0.01), whereas, Group-A males had significantly higher values for lower lip-chin length (P < 0.001), lower face height, soft-tissue chin-thickness (P < 0.01) and nasomental angle (P < 0.05). Group-B females had significantly higher values for lip-line (P < 0.05), soft-tissue thickness at labialis superior (P < 0.01), at labialis inferior and mandibular sulcus contour angle (P < 0.05) whereas, Group-A females had significantly higher values for upper lip length, lower lip-chin length (P < 0.01), lower face height (P < 0.001), nose length and lower lip to Sn-Pg′ (P < 0.05). There was an apparent sexual dimorphism was found in soft tissue pattern of both the groups. Conclusions: Angle′s Class-II division-2 malocclusion subjects have decreased lower lip-chin length and lower face height, while they have an increase lip-line, soft-tissue thickness at labrale superius, soft-tissue thickness at labrale inferius, total facial contour angle and mandibular sulcus contour angle.
AS ELECTROCHEMICAL TRANSDUCERS FOR 1 MERCURY SENSORS 2

6 The electrochemical behavior of mercury using different nanostructured screen-printed transducers 7 has been studied. The first underpotential deposition (UPD) was chosen as the best electrodicprocess 8 to detect low amounts of mercury on gold nanostructured electrodes. Several nanostructured 9 electrochemical transducers using carbon nanotubes, graphene oxide and gold nanoparticles were 10 generated, characterized and optimized for mercury determination in water. The transducer with a 11 nanohybrid surface of carbon nanotubes and gold nanoparticles was the best suited to solve the 12 analytical problem. For this sensor, a calibration plot from 0.5 to 50 μg/L was obtained in acidic 13 solutions of Hg(II) with anintraelectrodic reproducibility of 3% (n = 5). The detection limit was 0.2 μg/L 14 of mercury. The performance of the sensor was then evaluated using real samples of tap and river 15 water with good accuracy. 16
Spatial Spillover Effect of Public Infrastructure in Different GDP Sector Compositions: Spatial Panel Evidence in Eu-28 Regions

Spillovers have attracted wide attention in the areas of research in economics during the past decades. The reason for the interest in the topic lies in their important role in endogenous growth theory and the explanation of productivity growth. This paper investigates the spatial spillover of different types of public infrastructure on economic growth across EU-28 NUTS-II regions during 1995-2015. Particularly, we developed the previous studies by consedeing spillover in all types of the GDP sector composition including agriculture, industry, and services. The spatial Durbin panel data model is employed to consider spatial spillovers of both public infrastructure and economic growth. Empirical results show the positive spatial spillovers of communication infrastructure in all the sectors. The spillover effect of transport infrastructure is positive in the service and agricultural sector, whereas it is negative in the industry sector. Moreover, the spillover effect of local infrastructure is insignificant in all three sectors. Finally, we find significant evidence of positive geographical spillovers of economic growth implying spatially-growth dependency of regions to growth rate of neighboring regions. JEL Classification: H54, O47, C21
A Meta-Analysis of Outcomes of In Situ Reconstruction after Total or Partial Removal of Infected Abdominal Aortic Grafts?

Objective: To determine the most appropriate indication for total resection (TR) or partial resection(PR) of infected aortic grafts.Methods: A meta-analysis was conducted on the rates of early/late mortality, amputations and reinfection. A meta-regression was performed with 8 variables: patient age, male prevalence, presence of prosthetic duodenal fistula (PDF), presence of virulent or nonvirulent organisms, urgency, omentoplasty and follow-up.Results: For TR and PR, the rates of early mortality and reinfection were 16.8% and 10.5%, 11% and 27% respectively.For TR, the rates of early mortality and reinfection for in situ reconstruction with allografts and veins were 23% and 10.7%, 10.5% and 2.8% respectively.For TR, urgency, male gender and omentoplasty all had a negative correlation with early mortality. Omentoplasty had a positive correlation with late mortality. Male gender, PDF and virulent organisms had a negative correlation with reinfection, whereas nonvirulent organisms had a positive correlation. Presence of PDF and follow-up had a negative correlation with amputation, whereas male gender had a positive correlation. For PR, no statistical correlation was analyzable except a negative correlation between PDF and reinfection.Conclusion: For TR, operative mortality increases in males, and in emergencies, so total removal of the infected aortic graft seems not advisable, and alternative interventions should be considered. With regard to the risk of reinfection, TR appears recommendable in the presence of nonvirulent infectious organisms, but there is increased risk in the presence of virulent organisms and PDF, and so other optimal options may be discussed.For PR results were not analyzable except for a negative correlation in the presence of PDF.
Comparing Weighted Markov Chain and Auto-Regressive Integrated Moving Average in the Prediction of Under-5 Mortality Annual Closing Rates in Nigeria

In developing countries, childhood mortality rates are not only affected by socioeconomic, demographic, and health variables, but also vary across regions. Correctly predicting childhood mortality rate trends can provide a clearer understanding for health policy formulation to reduce mortality. This paper describes and compares two prediction methods: Weighted Markov Chain Model (WMC) and Autoregressive Integrated Moving Average (ARIMA) in order to establish which method can better predict the annual child mortality rate in Nigeria. The data for the study were Childhood Mortality Annual Closing Rates (CMACR) data for Nigeria from 1964-2017. The CMACR provides random values changing over time (annually), so we can analyze the mortality closing rate and predict the change range in the next state. Weighted Markov Chain (WMC), a method based on Markov theory, addresses the state and its transition procedures to describe a changing random time series. While the Autoregressive Integrated Moving Average (ARIMA) is a generalization of an Autoregressive Moving Average (ARMA) model. The findings indicate that the ARIMA model predicts CMACR for Nigeria better than WMC. The WMC entered in a loop after two iterations, and we could not use it effectively to predict the future values of CMACR.
Association of adipose tissue and skeletal muscle metrics with overall survival and postoperative complications in soft tissue sarcoma patients: an opportunistic study using computed tomography.

Background To determine the relationship between adipose tissue and skeletal muscle measurements on computed tomography (CT) and overall survival and major postoperative complications in patients with soft-tissue sarcoma (STS). Methods The retrospective study included 137 STS patients (75 men, 62 women; mean age, 53 years, SD 17.7; mean BMI, 28.5, SD 6.6) who had abdominal CT exams. On a single CT image, at the L4 pedicle level, measurements of visceral adipose tissue (VAT), subcutaneous adipose tissue (SAT), and skeletal muscle area and attenuation were obtained using clinical PACS and specialized segmentation software. Clinical information was recorded, including STS characteristics (size, depth, grade, stage, and site), overall survival, and postoperative complications. The relationships between CT metrics and survival were analyzed using Cox proportional hazard models and those between CT metrics and postoperative complications using logistic regression models. Results There were 33 deaths and 41 major postoperative complications. Measured on clinical PACS, the psoas area (P=0.003), psoas index (P=0.006), psoas attenuation (P=0.011), and total muscle attenuation (P=0.023) were associated with overall survival. Using specialized software, psoas attenuation was also associated with overall survival (P=0.018). Adipose tissue metrics were not associated with survival or postoperative complications. Conclusions In STS patients, CT-derived muscle size and attenuation are associated with overall survival. These prognostic biomarkers can be obtained using specialized segmentation software or routine clinical PACS.
Change in Diastolic Left Ventricular Filling After One Year of Antihypertensive Treatment

Background— It is well established that hypertensive patients with left ventricular (LV) hypertrophy have impaired diastolic filling. However, the impact of antihypertensive treatment and LV mass reduction on LV diastolic filling remains unclear. Methods and Results— Echocardiograms were recorded in 728 hypertensive patients with ECG-verified LV hypertrophy (Cornell voltage-duration or Sokolow-Lyon) at baseline and after 1 year of blinded treatment with either losartan or atenolol-based regimen. Systolic and diastolic blood pressures (BP) were reduced on average 23/11 mm Hg; isovolumic relaxation time and E/A ratio became more normal, and LV inflow deceleration time prolonged (all P<0.001). Directionally opposite changes in isovolumic relaxation time (IVRT) and deceleration time indicate improvement in active LV relaxation and passive chamber stiffness during early diastole. Prevalences of normal LV filling increased, abnormal relaxation and pseudonormalization decreased, and restrictive filling pattern r.
National Stock Exchange Stock and Index Price Direction Prediction using Back-propagation Artificial Neural Network

: Stock price are highly volatile, non linear and random in nature. Soft computing technique, such as Artificial Neural Network is capable to solve non liner problem. We find properly tuned back propagation feed forward neural network can effectively predict price direction. Here we design price prediction generalize model that can predict price direction of random time series. Research study used National Stock Exchange benchmark stock index and top ten weighted index stock. Technical indicators are applied as input to the model. Model used daily stock data from January 2006 to June 2015. Performance of model are measured using hit rate. After properly tuning ANN, experimental result show that model can effectively improve price prediction .
Palbociclib added to ongoing endocrine therapy for hormone receptor-positive HER2-negative metastatic breast cancer: A case report series

Palbociclib is a potent cyclin-dependent kinase (CDK)4/6 inhibitor that disrupts cell cycle progression and has been recently approved in combination with an aromatase inhibitor or fulvestrant as first- and second-line treatment in hormone receptor (HR)+, human epidermal growth factor receptor (HER)2- metastatic breast cancer. There is evidence that palbociclib may reverse endocrine therapy resistance and that it may also be added to ongoing endocrine therapy beyond progression to obtain clinical benefit. The aim of the present study was to explore this possibility in 5 patients who received palbociclib + fulvestrant following disease progression while under treatment with fulvestrant alone. The median progression-free survival was not reached during a median follow-up of 25 months, and the most frequent best response was stable disease. Three patients remained under treatment on the last re-evaluation. All patients had highly endocrine-sensitive disease and had previously received fulvestrant for ≥12 months. The hypothesis that a selected subpopulation of patients with HR+/HER2- metastatic breast cancer may benefit from the addition of palbociclib to ongoing endocrine therapy beyond disease progression merits further investigation.
Assessment of Criteria for Performance Excellence (KPKU) and Firm Performance: Evidence from Indonesia

This study aims to examine whether the assessment of Criteria for Performance Excellence (KPKU) is related to the firm performance of States-Owned Enterprise (SOE) in Indonesia. This study uses 82 firms-year observations from 19 State-Owned Enterprise listed on the Indonesia Stock Exchange (IDX) for the period 2009 to 2018. This study found that KPKU assessment was positively related to firm performance. This shows that KPKU assessment can be a signal that the company has good performance. The study also found that the positive relationship between KPKU assessment and company performance is stronger in companies audited by Big 4 and in big-sized companies. This study is the first research that discusses the relationship between KPKU assessment and firm performance. This study may be useful for practitioners and academics that are interested in the subject of SOE performance assessment. The results suggest to conduct a regular KPKU assessment because it can be useful to provide a positive signal for shareholders and potential investors.
Determination of Factors Impacting Smoking Habits of University Students: An Empirical Analysis from Turkey

Abstract The aim of this study is to determine the main factors impacting cigarette smoking habits of university students. In order to achieve this aim, the primary data obtained from face to face questionnaire conducted with 260 university students was used for the Zero the Altered Poisson Regression Model. The results of the study showed that the students’ age ranged from 18 to 35 years and 55.4 percent of these were women. Besides, twenty-three percent of the total students smoked, and 83.3 percent of them were men. Average monthly cigarette consumption amount was five packs per student. The results highlighted that of the 19 factors that effected on smoking, 16 were statistically significant. If the prohibitions applied by the government on smoking are implemented, and cigarette taxes are increased, it could be decreased smoking rates in young people. By being conducting effective campaigns related to public health on social and real media, the smoking rate could be dec reased considerably.
Network Analysis of Local Food in California: A Study of Farmers' Markets in Los Angeles and Their Farm Supply Chains

This paper examines the geography of local food through a spatial analysis of farms and farmers’ markets. It draws on two themes in the geographical literature on local food, which focus on territorial and proximity definitions on one hand and on relationality on the other. Through GIS analysis, this paper explores spatial patterns of ninety-one farmers’ markets in Los Angeles County, California, USA; spatial patterns of 282 farms that supplied a sample of thirty-three markets; and intra-urban patterns of those supply chains. The results show an uneven geography of farms across California that supplied the sampled markets, but also show that farms travel just as far to markets in working-class neighborhoods as to wealthier neighborhoods. Conclusions explain how integrating territorial and relational conceptions of local food provide insights into the complex spatiality of production and consumption, and how local food can be understood as an interdependence between places.
The Use of the Interactive White Boards in Tatweer Primary Schools in Saudi Arabia

:This paper is a part of a larger study aimed at investigating the use of the Interactive White Boards (IWBs) in primary schools that participated in the Tatweer project in the city of Jeddah in Saudi Arabia. 587 teachers (301 females and 286 males) completed a self-report questionnaire specially designed for this study, but also drawing on earlier research. Twenty teachers (10 female and ten male) were interviewed, of these seven female teachers were also observed teaching in their classrooms or the learning resources rooms. The majority of teachers in this study reported that they used IWBs infrequently and only with a few interactive features, indicating that their choices were limited by their current technical capability. Moreover, they presented only a basic repertoire of pedagogy with technology because they mainly used IWBs for whole class teaching. They occasionally varied this, such as when groups of students used the boards. Therefore, they showed a limited range of IWBs use in their classrooms. However, in this study, teachers’ experience in using IWBs and the opportunity to receive training were the two important factors to determine teachers' capability in using IWBs.
Determinants and Dimensions of Household Food Insecurity Risks in Hargeisa City, Somaliland

Even though there is long-held belief that urban populations are better off, or even favoured than rural populations, the recent food and financial crises have highlighted the problem of urban food insecurity in developing countries. The problem of urban food insecurity in Somaliland has received little attention despite its increasing importance and far reaching ramifications. Hence, the overall objective of this study was to examine the determinants and dimensions of food insecurity risks among urban households in Hargeisa city. To do so, both descriptive statistics and econometric analysis were employed. Descriptive statistics used Foster, Greer and Thorbeck distributional measure of food insecurity while econometric analysis used binary logistic regression model to analyze the data of a set of socio-economic variables as explanatory variables and food insecurity as independent variable. The head count index shows that 53.2 % of the total households are below the food insecurity line. The food insecurity gap and severity were 18.9 % and 6.4 %, respectively. The result of the logistic regression model estimate indicates that out of the 11 factors included, 5 were found to have a significant influence on the probability of being food insecure at less than 1 % significance level. The variables considered were household size, owning saving account, household head education, and access to remittance and gifts and average monthly income of households. Efforts should be made to improve income earning capacity of households, their education level with particular focus on vocational training, reduce household size with a view to reducing their dependency ratio and access of financial services to the needy and trained people needs to be provided with proper targeting standard.
Nauclea latifolia Sm. Leaf Extracts Extenuates Free Radicals, Inflammation, and Diabetes-Linked Enzymes

This study was carried out to assess the in vitro antioxidant, anti-inflammatory and antidiabetic effects of Nauclea latifolia (Sm.) leaf extracts. Ethanolic (NLE) and aqueous (NLA) extract of N. latifolia leaves were prepared and assessed for their anti-inflammatory activity, antioxidant potential, α-amylase and α-glucosidase inhibitory activities, and the mechanism of enzyme inhibition in vitro using standard established methods. From the results, phytochemicals such as flavonoids, phenolics, glycosides, and tannins were detected in both extracts of N. latifolia with NLE having a significantly (p < 0.05) higher phytochemical content. NLE displayed significantly (p < 0.05) better total antioxidant capacity, reducing power, 2,2-diphenyl-2-picrylhydrazyl, and hydrogen peroxide radical scavenging activities. For anti-inflammatory activities, 70.54 ± 2.45% albumin denaturation inhibition was observed for NLE while 68.05 ± 1.03% was recorded for NLA. Likewise, 16.07 ± 1.60 and 14.08 ± 1.76% were obtained against hypotonic solution and heat-induced erythrocyte haemolysis, respectively, for NLE while 20.59 ± 4.60 and 24.07 ± 1.60% were respective NLA values. NLE (IC50: 4.20 ± 0.18 and 1.19 ± 0.11 mg/mL) and NLA (IC50: 11.21 ± 0.35 and 2.64 ± 0.48 mg/mL) α-glucosidase and α-amylase inhibitory activities were dose-dependent with uncompetitive and competitive inhibition elicited, respectively, by the extracts. A significant positive association (p < 0.01 and 0.05) was identified between antioxidant activity and carbohydrate-metabolising enzyme inhibitory activity. The obtained result suggests N. latifolia leaf could serve as an alternative candidate for managing diabetes mellitus due to its antioxidant and anti-inflammatory association with diabetes-linked enzymes.
BED FORM DEFORMATION DUE TO UPSTREAM GROUP PILES

Deformation of bed forms by passing through a group of vertical piles installed upstream in an open channel was examined experimentally. With Froude number the heights and lengths of dunes are increased and the steepness of dunes decreases. The heights of piles were found to have negligible impact on the variation of bed forms. The pile diameter is a significant factor that causes the reduction in the dimensions of dunes. Increase in number of piles per unit area defined as a pile density brings about the decrease in the size of dune as much as 60%. However, there exists an upper limit of the pile density beyond which the deformation of dune becomes independent of the density. The steepness of dunes becomes steeper with increase of the density. The deformed bed forms resume their original states at a distance downstream X/L≈ 6 from the end of pile zone. Introduction Depending on the flow parameters and sediment properties, an alluvial stream may undergo different bed forms. For the lower regime of a subcritical flow, the stream bed can exhibit ripples and dunes with the water surface being approximately flat. Kennedy(1969) argued that the occurrence of bed forms is due to (1) the result of an orderly pattern of scour and deposition, (2) the instability phenomenon and (3) the flow parameters and sediment properties. Yalin(1977) pointed out that the dunes are caused by a discontinuity(ridge) of a plane initial bed, which induces an alternation in velocity profile through disturbance of turbulence structure and in consequence the velocity alternation is resulted in the decrease of sediment transport, the growth of accretion must take place, and the variation of bed level by the Exner equation must be accompanied. Based on the aforementioned reasonings, any physical addition to a flow, which causes an alternation in the flow structure and in the alluvial stream bed features, will bring about change in sediment transport. Such change will lead to either increase or decrease the magnitudes of bed form geometries such as the dimensions of dunes. Placing piles on the stream bed may be one of the additions resulting in the alteration, possibly reduction, of the dimensions of dunes. In alluvial streams, when the troughs of dunes pass hydraulic structures, substantial part of their foundation may be exposed to flow and it may endanger the safety of structures. Therefore, for proper management, maintenance and safe design of hydraulic structures, it is very