Miracle-dz/UniFAR-FTUs huggingface dataset:
ERRATUM: “SEARCH FOR DARK MATTER ANNIHILATION SIGNALS FROM THE FORNAX GALAXY CLUSTER WITH H.E.S.S.” (2012, ApJ, 750, 123)

A. Abramowski1, F. Acero2, F. Aharonian3,4,5, A. G. Akhperjanian5,6, G. Anton7, A. Balzer7, A. Barnacka8,9, U. Barres de Almeida10,33, Y. Becherini11,12,34, J. Becker13, B. Behera14, K. Bernlöhr3,15, E. Birsin15, J. Biteau12, A. Bochow3, C. Boisson16, J. Bolmont17, P. Bordas18, J. Brucker7, F. Brun12, P. Brun9, T. Bulik19, I. Büsching13,20, S. Carrigan3, S. Casanova13, M. Cerruti16, P. M. Chadwick10, A. Charbonnier17, R. C. G. Chaves3, A. Cheesebrough10, A. C. Clapson3, G. Coignet21, G. Cologna14, J. Conrad22, M. Dalton15, M. K. Daniel10, I. D. Davids23, B. Degrange12, C. Deil3, H. J. Dickinson22, A. Djannati-Ataı̈11,34, W. Domainko3, L. O’C. Drury4, G. Dubus24, K. Dutson25, J. Dyks8, M. Dyrda26, K. Egberts27, P. Eger7, P. Espigat11,34, L. Fallon4, C. Farnier2, S. Fegan12, F. Feinstein2, M. V. Fernandes1, A. Fiasson21, G. Fontaine12, A. Förster3, M. Füßling15, Y. A. Gallant2, H. Gast3, L. Gérard11,34, D. Gerbig13, B. Giebels12, J. F. Glicenstein9, B. Glück7, P. Goret9, D. Göring7, S. Häffner7, J. D. Hague3, D. Hampf1, M. Hauser14, S. Heinz7, G. Heinzelmann1, G. Henri24, G. Hermann3, J. A. Hinton25, A. Hoffmann18, W. Hofmann3, P. Hofverberg3, M. Holler7, D. Horns1, A. Jacholkowska17, O. C. de Jager20, C. Jahn7, M. Jamrozy28, I. Jung7, M. A. Kastendieck1, K. Katarzysńki29, U. Katz7, S. Kaufmann14, D. Keogh10, D. Khangulyan3, B. Khélifi12, D. Klochkov18, W. Kluźniak8, T. Kneiske1, Nu. Komin21, K. Kosack9, R. Kossakowski21, H. Laffon12, G. Lamanna21, D. Lennarz3, T. Lohse15, A. Lopatin7, C. -C. Lu3, V. Marandon11,34, A. Marcowith2, J. Masbou21, D. Maurin17, N. Maxted30, M. Mayer7, T. J. L. McComb10, M. C. Medina9, J. Méhault2, R. Moderski8, E. Moulin9, C. L. Naumann17, M. Naumann-Godo9, M. de Naurois12, D. Nedbal31, D. Nekrassov3, N. Nguyen1, B. Nicholas30, J. Niemiec26, S. J. Nolan10, S. Ohm3,25,32, E. de Oña Wilhelmi3, B. Opitz1, M. Ostrowski28, I. Oya15, M. Panter3, M. Paz Arribas15, G. Pedaletti14, G. Pelletier24, P.-O. Petrucci24, S. Pita11,34, G. Pühlhofer18, M. Punch11,34, A. Quirrenbach14, M. Raue1, S. M. Rayner10, A. Reimer27, O. Reimer27, M. Renaud2, R. de los Reyes3, F. Rieger3,33,35, J. Ripken22, L. Rob31, S. Rosier-Lees21, G. Rowell30, B. Rudak8, C. B. Rulten10, J. Ruppel13, V. Sahakian5,6, D. A. Sanchez3, A. Santangelo18, R. Schlickeiser13, F. M. Schöck7, A. Schulz7, U. Schwanke15, S. Schwarzburg18, S. Schwemmer14, F. Sheidaei11,20,34, J. L. Skilton3, H. Sol16, G. Spengler15, Ł. Stawarz28, R. Steenkamp23, C. Stegmann7, F. Stinzing7, K. Stycz7, I. Sushch15,36, A. Szostek28, J.-P. Tavernet17, R. Terrier11,34, M. Tluczykont1, K. Valerius7, C. van Eldik3, G. Vasileiadis2, C. Venter20, J. P. Vialle21, A. Viana9, P. Vincent17, H. J. Völk3, F. Volpe3, S. Vorobiov2, M. Vorster20, S. J. Wagner14, M. Ward10, R. White25, A. Wierzcholska28, M. Zacharias13, A. Zajczyk2,8, A. A. Zdziarski8, A. Zech16, and H. -S. Zechlin1
The Relationship of Parent Support and Child Emotional Regulation to School Readiness

Using data from the longitudinal Early Head Start Research and Evaluation Project that were obtained when children were 14 through 60 months old, this study aims to explore the transactional effects between parent supportiveness and child emotion regulations skills. An autoregressive model with cross-lagged paths was utilized to examine the developmental trajectories of parent supportiveness and child emotion regulation, the directions of transactional relationships between them, and the transactional effects on the prediction of child cognitive school readiness. Significant autoregressive effects were found in both parent supportiveness and child emotion regulation trajectories. Significant concurrent and longitudinal transactional effects between these two processes were documented. The effects of child emotion regulation, parent supportiveness, and their transactional effects significantly predicted cognitive school readiness. This study exemplifies the use of archival longitudinal data to move beyond current unidirectional empirical understandings of child early psychosocial development toward more integrated perspectives. Equally important, the results provide critical insights for the timing of interventions as well as the involvement of parents in early intervention programs that early childhood educators and family services providers can benefit from.
Field maturity detection via interferometric synthetic aperture radar images time-series: a case study for maize crop

ABSTRACT Detecting the field maturity moment for maize (Zea mays L.) crop represents a relevant point to estimate its optimal harvest time. Knowing the optimal harvest time (defined by grain moisture content) at the end of the crop season is a major concern for maize farmers, as it could lead to substantial economic losses if not harvested on time. For this crop, optimal harvest time usually occurs 3–4 weeks after field maturity, depending on weather conditions. Therefore, this study focused on the interferometric coherence time-series analysis at the end of the maize crop season, to indirectly estimate the field maturity. For such purpose, a coherence object-based change detection method using Sentinel-1 SAR images was developed aiming to estimate the potential field maturity time. These estimations were assessed using an independent data set of field maturity dates obtained through field inspection and crop growth modelling. The technique was tested over 52 fields in the northwest region of Kansas, United States, with a detection rate of 80%, and a field maturity estimation error of 10 days (assessed with the root mean square error). The proposed method constitutes a promising approach to estimating the maize field maturity in near-real time, determining the field harvest readiness, and developing a decision support tool to assist farmers in prioritizing the allocation of fields at harvest time.
Importance of Clouds to the Decaying Trend and Decadal Variability in the Arctic Ice Cover

The areal extent of the sea ice cover in the Arctic Ocean has declined in the last 40 years with increased decadal variability. The trend is clearly influenced by the radiation balance over all seasons. A cloudiness increase in the fall, winter and spring contributes to a reduction in the absolute amount of net longwave radiation at the sea surface. In the summer, the reduced cloud cover has led to an increase in shortwave radiation, permitting more net outgoing radiation, and yielding a small increase in the total incoming radiation. All of these trends promote ice reduction, and may suggest the importance of clouds during a possible global warming in the near future. The effects of clouds and radiation are comparable with the albedo reduction associated with more open water, which absorbs more solar radiation in the summer. Analyses of the decadal variabilities reveal qualitatively the same effects as those of the radiation on the ice cover.
Output-Oriented Agricultural Subsidy Design

Many governments subsidize the agricultural industry, trying to raise the market outputs either for domestic needs or for export. In many countries, particularly developing countries, the producers’ market may be fragmented, involving a large number of farmers with variable productivity levels. The format of subsidies can have significantly different implications for farmers in different market segments. In this study, we examine four types of subsidies. A planting subsidy is paid to a farmer based on the amount of input, and a harvesting subsidy compensates a farmer for the cost incurred during the process of output collection and distribution. The government may also offer a combined subsidy under which a farmer gets paid for both planting and harvesting, or it may offer a selective subsidy under which a farmer can choose to be subsidized on either planting or harvesting but not both. In addition to examining the efficiency of budget spending and social welfare, two common performance measures studied in various contexts, we thoroughly analyze the implications of subsidies on the output and wealth distributions among the farmers. In general, subsidizing on harvesting or overly compensating on planting can increase the disparity among the farmers, whereas an appropriate level of planting subsidy helps to balance the distributions of the farmers’ output and profit. A comprehensive evaluation of the government’s policies reveals that the harvesting subsidy, while inducing the most dispersed output and profit distributions, leads to the most efficient use of input resources and the highest social welfare. The planting subsidy, although being the most effective in balancing the farmer income for a moderate output increase, performs poorly in budget spending, resource usage, and welfare generation when the government sets an aggressive target for output increase. In such a situation, the combined subsidy can offer the most evenly distributed farmer income, with the least amount of budget needed to achieve the output target. This paper was accepted by David Simchi-Levi, operations management. Funding: This work was partially supported by the National Natural Science Foundation of China [Grants 71471062, 72032001 and 71972071] and the Shanghai Sailing Program [Grant 22YF1451000]. Supplemental Material: The online appendix is available at https://doi.org/10.1287/mnsc.2023. 4749 .
Numerical Modeling and Simulation of a Spark-Ignition Engine Fueled with Ammonia-Hydrogen Blends

Carbon-free fuels, in particular ammonia and hydrogen, could play a significant role in the decarbonization of the mobility sector. In this work, the authors assessed the operation of a light-duty spark-ignition engine fueled with an ammonia–hydrogen blend (85% ammonia and 15% hydrogen by volume) using a 1D predictive model. Three-dimensional computations have been used in order to verify the reliability of the 1D model. The addition of hydrogen to the air–fuel mixture allows the operating capacity of the engine to be extended with respect to neat ammonia fueling. The engine can be properly regulated between 1500 rpm and 3000 rpm. Its operating range reduces as engine speed increases, and it cannot run at 6000 rpm. This is due to different engine operating constraints being exceeded. The maximum engine torque is about 240 Nm and is reached at 1500 rpm. The engine efficiency ranges between 42% and 19%, and the specific fuel consumption varies from about 350 g/kWh to about 750 g/kWh. The results provide both performances and operating ranges of the engine allowing us to define optimized engine maps obtained by means of a constrained optimization.
Optical and X-Ray Observations of IGR J00291+5934 in Quiescence

We report on optical and X-ray observations of the accretion-powered millisecond pulsar IGR J00291+5934 in quiescence. Time-resolved I-band photometry has been obtained with the 4.2 m William Herschel Telescope, while a 3 ks Chandra observation provided contemporaneous X-ray coverage. We found an unabsorbed 0.5-10 keV X-ray flux of 1 × 10−13 erg cm−2 s−1, which implies that the source was in quiescence at the time of the optical observations. Nevertheless, the optical I-band light curve of IGR J00291+5934 shows evidence for strong flaring. After removal of the strongest flares, we find evidence for an orbital modulation in the phase-folded I-band light curve. The overall modulation can be described by effects resulting from the presence of a superhump. Comparing our light curve with that reported recently we find evidence for a change in the quiescent base level. Similar changes have now been reported for four soft X-ray transients, implying that they may be a common feature of such systems in quiescence. Furthermore, the maximum in our folded light curve occurs at a different phase than observed before.
Design, Synthesis and Bioactivity Evaluation of Novel 2-(pyrazol-4-yl)-1,3,4-oxadiazoles Containing an Imidazole Fragment as Antibacterial Agents

Imidazole alkaloids, a common class of five-membered aromatic heterocyclic compounds, exist widely in plants, animals and marine organisms. Because of imidazole’s extensive and excellent biological and pharmacological activities, it has always been a topic of major interest for researchers and has been widely used as an active moiety in search of bioactive molecules. To find more efficient antibacterial compounds, a series of novel imidazole-fragment-decorated 2-(pyrazol-4-yl)-1,3,4-oxadiazoles were designed and synthesized based on our previous works via the active substructure splicing principle, and their bioactivities were systematically evaluated both in vitro and in vivo. The bioassays showed that some of the target compounds displayed excellent in vitro antibacterial activity toward three virulent phytopathogenic bacteria, including Xanthomonas oryzae pv. oryzae (Xoo), Xanthomonas axonopodis pv. citri (Xac) and Pseudomonas syringae pv. actinidiae (Psa), affording the lowest EC50 values of 7.40 (7c), 5.44 (9a) and 12.85 (9a) μg/mL, respectively. Meanwhile, compound 7c possessed good in vivo protective and curative activities to manage rice bacterial leaf blight at 200 μg/mL, with control efficacies of 47.34% and 41.18%, respectively. Furthermore, compound 9a showed commendable in vivo protective and curative activities to manage kiwifruit bacterial canker at 200 μg/mL, with control efficacies of 46.05% and 32.89%, respectively, which were much better than those of the commercial bactericide TC (31.58% and 17.11%, respectively). In addition, the antibacterial mechanism suggested that these new types of title compounds could negatively impact the cell membranes of phytopathogenic bacteria cells and cause the leakage of the intracellular component, thereby leading to the killing of bacteria. All these findings confirm that novel 2-(pyrazol-4-yl)-1,3,4-oxadiazoles containing an imidazole fragment are promising lead compounds for discovering new bactericidal agents.
Strategies involving low-molecular-weight heparin for the treatment and prevention of venous thromboembolism in patients with obesity: A systematic review and meta-analysis

Introduction Recent studies have indicated that the dosage of LMWH in patients with specific weights may be controversial. Therefore, we conducted a meta-analysis to explore an appropriate dosage of LMWH for the prevention and treatment of venous thromboembolism (VTE) in patients with obesity. Materials and methods We searched the PubMed, EMBASE, and Cochrane Library databases up to July 23, 2022. Study selection, bias analysis, and information extraction were performed by three independent reviewers. The occurrence or recurrence of VTE and bleeding events were the primary outcomes we assessed. Results Eleven studies (a total of 6266 patients) were included in the prevention group, and 6 studies (a total of 3225 patients) were included in the treatment group. For VTE prophylaxis, compared with the standard-dosage group, the high-dosage group had a lower incidence of VTE (OR: 0.47, 95% CI: 0.27-0.82, P=0.007) and a similar incidence of bleeding events (OR: 0.86, 95% CI: 0.69-1.08, P=0.020). For VTE therapy, compared to the standard-dosage group, the reduced-dosage group had a similar incidence of VTE recurrence (OR: 0.86, 95% CI: 0.11-6.84, P=0.89) but a lower incidence of bleeding events (OR: 0.30, 95% CI: 0.10-0.89, P=0.03). Conclusion In patients with obesity, increasing the dosage of LMWH is a more appropriate option for the prevention of VTE. Due to the limited evidence, reducing the therapeutic dosage of LMWH requires careful consideration. Larger-scale, well-designed randomized controlled trials are necessary. Systematic Review Registration https://www.crd. york.ac. uk/prospero/display_record. php? , identifier ID=CRD42022298128.
COMPARATIVE STUDIES ON CURE CHARACTERISTICS AND MECHANICAL PROPERTIES OF OIL PALM BIOMASS FILLED NATURAL RUBBER COMPOSITES

Oil palm is categorised as the most important agricultural crop in Malaysia occupying about 70% of the agricultural land. The palm oil industry is one of the biggest contributors to Malaysia’s Gross National Income (GNI). However, the rapid development of the palm oil industry causes high production of palm oil waste which is a worrying environmental issue these days. As the need to promote sustainable, renewable and clean energy keeps rising, researchers have taken a keen interest in utilising palm oil waste as a source of biomass. Palm oil waste such as palm kernel shell (PKS) is a great source of valuable biomass and readily available in large amounts which can then be transformed into biochar and activated carbon via pyrolysis and activation processes, respectively. By producing palm kernel shell biochar (PKSB) and activated palm kernel shell (APKS) derived from palm oil waste, they can potentially be used as potential bio-fillers in rubber composites. The research aimed to study the effect of different loading of PKSB and APKS in natural rubber (NR) composite since they have higher carbon content, porosity and surface area compared to other biomass fillers. The surface morphology analysis by scanning electron microscopy, cure characteristics, swelling measurements, and mechanical properties was analysed. APKS was observed to have well-developed pores that could provide a high surface area of contact resulting in improved mechanical interlocking between filler and rubber matrix. Comparisons were made between PKSB, APKS and other bio-fillers such as coconut fibre (CF), bamboo charcoal (BC) and untreated kenaf (UK). The cure characteristics for PKSB showed a high range of maximum torque (M H ) values (11-23 dN.m), better in ts 2 (1 min) and t 90 (2-3 min), whereas the M H values for APKS were slightly lower and longer in t 90 which were 14-15 dN.m and 2-4 min, respectively. PKSB also showed a better swelling percentage (226%-329%) which would indicate high crosslink density compared to APKS (305%-336%). Moreover, APKS showed better tensile strength (8-18 MPa) and elongation at break (519%-669%) as the filler loading increased in comparison with PKSB which recorded a tensile strength of 5-14 MPa and elongation at break of 385%-561%. Based on the results, it can be concluded that the optimum value of APKS filler loading ratio in NR composite is 40 phr as 40 phr of APKS filled NR composite had the highest mechanical properties compared to the other filler loading ratios. Both PKSB and APKS have great potential to be used and commercialised as semi-reinforcing fillers in the rubber industry. This way, PSKB and APKS are able to provide a sustainable alternative to existing petroleum-based fillers and could help to reduce the abundance of palm oil waste while producing high-performance rubber-based products.
New Drug Development strategies with special reference to the endocarp of multifaceted agriculture crop – Cocos nucifera Linn

Coconut shell botanically represents the hard endocarp from the fruit of Cocos nucifera Linn. It is the usually discarded part of the plant with folklore claim in metabolic disorders.Being an inexpensive and easily availablenatural product with ethno medicinal significance, it seems highly relevant to scientifically validate the pharmaceutical implications of the drug. Till date, the new drug development strategies based on quality and efficacy parameters for the crude drug sample of Coconut shell has not been developed. The present study was intended to develop and scientifically validate the quality, purity, safety, potency and efficacy parameters of Coconut shell and thereby exploring the new drug development strategies for the drug. Materials andmethods: The study focused on the screening ofCoconut shell based on macroscopic, microscopic, organoleptic, histo-chemicaland HPTLC studies. Results:Characteristic presence of thin walled fibres, fibrosclereids,lignins and tannins were observed in themicroscopic analysis of Coconut shell. HPTLC studies also exemplifiedthe detailed bioactive chemical profile of Coconut shell.Conclusion: The study outcome suggestsCoconut shell as a novel reliable source of bioactive phytoconstituents with broad prospective in new drug development process.
Synchronization of two unidirectionally coupled multimode semiconductor lasers

The synchronization of two unidirectionally coupled multimode semiconductor lasers was reported in the feedback/injection configuration. The transmitter was subjected to a weak-to-moderate optical feedback. Multimode chaotic output exhibited antiphase dynamics and multiple coexisting attractors. Results showed that the antiphase dynamics eliminated the need for modal output synchronization. The possibility of synchronization collapsed for identical lasers operating with identical or different parameters.
Nanobacterial Cellulose from Kombucha Fermentation as a Potential Protective Carrier of Lactobacillus plantarum under Simulated Gastrointestinal Tract Conditions

Kombucha bacterial cellulose (KBC), a by-product of kombucha fermentation, can be used as a biomaterial for microbial immobilization. In this study, we investigated the properties of KBC produced from green tea kombucha fermentation on days 7, 14, and 30 and its potential as a protective carrier of Lactobacillus plantarum, a representative beneficial bacteria. The highest KBC yield (6.5%) was obtained on day 30. Scanning electron microscopy showed the development and changes in the fibrous structure of the KBC over time. They had crystallinity indices of 90–95%, crystallite sizes of 5.36–5.98 nm, and are identified as type I cellulose according to X-ray diffraction analysis. The 30-day KBC had the highest surface area of 19.91 m2/g, which was measured using the Brunauer–Emmett–Teller method. This was used to immobilize L. plantarum TISTR 541 cells using the adsorption–incubation method, by which 16.20 log CFU/g of immobilized cells was achieved. The amount of immobilized L. plantarum decreased to 7.98 log CFU/g after freeze-drying and to 2.94 log CFU/g after being exposed to simulated gastrointestinal tract conditions (HCl pH 2.0 and 0.3% bile salt), whereas the non-immobilized culture was not detected. This indicated its potential as a protective carrier to deliver beneficial bacteria to the gastrointestinal tract.
Exploring pta Alternatives in the Development of Ruthenium–Arene Anticancer Compounds

Organoruthenium pyrithione (1-hydroxypyridine-2-thione) complexes have been shown in our recent studies to be a promising family of compounds for development of new anticancer drugs. The complex [(η6-p-cymene)Ru(pyrithionato)(pta)]PF6 contains phosphine ligand pta (1,3,5-triaza-7-phosphaadamantane) as a functionality that improves the stability of the complex and its aqueous solubility. Here, we report our efforts to find pta alternatives and discover new structural elements to improve the biological properties of ruthenium anticancer drugs. The pta ligand was replaced by a selection of phosphine, phosphite, and arsine ligands to identify new functionalities, leading to improvement in inhibitory potency towards enzyme glutathione S-transferase. In addition, cytotoxicity in breast, bone, and colon cancers was investigated.