Miracle-dz/UniFAR-FTUs huggingface dataset:
Ground‐based validation of CALIPSO observations of dust and smoke in the Cape Verde region

Ground‐based Raman lidar measurements during the second Saharan Mineral Dust Experiment (SAMUM‐2) in 2008 were used for validation of measurements of the lidar aboard the Cloud‐Aerosol Lidar and Infrared Pathfinder Satellite Observations (CALIPSO) satellite within the dusty environment of the Cape Verde region. SAMUM‐2 featured two one‐month campaigns in January/February and May/June 2008 to cover different modes of aerosol transport to the tropical Atlantic: dust from northern Africa and biomass‐burning smoke from western Africa during winter, and pure Saharan dust during summer. During the investigated time period, 33 CALIPSO overflights occurred at a distance of less than 500 km from the location of the ground‐based lidar. Fifteen out of these 33 cases were found suitable for comparing the findings of the two instruments. The parameters for this comparison are the particle backscatter coefficient at 532 and 1064 nm, the extinction coefficient, the lidar ratio (aerosol type), and the particle depolarization ratio at 532 nm, as well as the backscatter‐related Ångström exponent for the wavelength pair 532/1064 nm. Best agreement was found for the 532 nm backscatter coefficient, while the 532 nm extinction coefficient is underestimated by up to 30%. The latter is due to the use of an effective dust lidar ratio that gives reliable backscatter coefficients but is not suitable to transform these to extinction coefficients. CALIPSO particle depolarization ratios provided in the current (version 3.01) aerosol profile product were found to be affected by a computing error and should be calculated from the perpendicular and total particle backscatter coefficients provided in the same data file. CALIPSO aerosol classification was found to be mostly correct but a demand for homogeneous aerosol layers could improve the retrieval. Suggestions for the improvement of the CALIPSO retrieval by introducing iterative procedures are provided.
Microbiota Thrombus Colonization May In�uence Athero-ThrombosIs in Hyperglycemic Patients With ST Segment Elevation Myocardial Infarction (STEMI). MARIANELLA Study

Objectives. We examined the association of the coronary thrombus microbiota and relative metabolites with major adverse cardiovascular events (MACE) in hyperglycemic patients with ST segment elevation infarction (STEMI). Methods. We undertook an observational cohort study of 146 �rst STEMI patients treated with primary percutaneous coronary intervention (PPCI) and thrombus-aspiration (TA). Patients were clustered, based on admission blood glucose levels, in hyperglycemic (>140 mg/dl) and normoglycemic (<140 mg/dl). We analyzed gut and thrombus microbiota in all patients. Moreover, we assessed TMAO, CD40L and von Willebrand Factor (vWF) in coronary thrombi. Cox regressions were used for the association between Prevotellaspp and TMAO terziles and MACE. MACE endpoint at 1 year included death, re-infarction, unstable angina. we observed a signi�cantly different prevalence of both Prevotellaspp between with (n=56) and those with normal glucose levels (n=90). The abundance of Prevotella increased in hyperglycemic vs normoglycemic patients whereas the contrary was observed for Alistipes. Interestingly, coronary thrombus, the content of Prevotella was associated with admission blood glucose levels (p<0.01), thrombus dimensions (p<0.01), TMAO, CDL40 (p<0.01) and vWF (p<0.01) coronary thrombus contents. Multivariate Cox-analysis disclosed a reduced survival in patients with high levels of Prevotella and TMAO in coronary thrombus as compared to patients with low levels of Prevotella and TMAO, after 1-year follow up. statistically signi�cant. The study population was equally distributed for age (p = 0.807). To evaluate the independent contribution of hyperglycaemia in thrombus Prevotella and TMAO levels, we performed a correlation between Prevotella and TMAO levels in coronary thrombus and blood glucose level during STEMI. Risk adjusted Cox-regression analysis curves showing survival from severe disease through days of hospitalization. Cox models were adjusted for; age, diabetes, hypertension, diabetes, new diabetes, dyslipidemia, cigarette smoking, BMI, systolic blood pressure, total cholesterol, HDL and LDL-cholesterol levels, triglycerides, TIMI scores, lesions of RCA and LM, dual antiplatelet therapy and ejection fraction. To investigate the effects of Prevotella and TMAO thrombi expressions on cardiovascular endpoints, we evaluated STEMI outcomes at 1-year follow-up thrombus contents did not change despite a similar severity of atherosclerotic disease at baseline and asimilar glycemic control both at discharge and at follow-up. These observations suggest that on admission hyperglycemia may play a pivotal role in the increase of coronary thrombus burden, during STEMI, favoring thrombus colonization and proliferation by Prevotella.
Decadal surface water quality trends under variable climate, land use, and hydrogeochemical setting in Iowa, USA

Understanding how nitrogen fluxes respond to changes in agriculture and climate is important for improving water quality. In the midwestern United States, expansion of corn cropping for ethanol production led to increasing N application rates in the 2000s during a period of extreme variability of annual precipitation. To examine the effects of these changes, surface water quality was analyzed in 10 major Iowa Rivers. Several decades of concentration and flow data were analyzed with a statistical method that provides internally consistent estimates of the concentration history and reveals flow‐normalized trends that are independent of year‐to‐year streamflow variations. Flow‐normalized concentrations of nitrate+nitrite‐N decreased from 2000 to 2012 in all basins. To evaluate effects of annual discharge and N loading on these trends, multiple conceptual models were developed and calibrated to flow‐weighted annual concentrations. The recent declining concentration trends can be attributed to both very high and very low discharge in the 2000s and to the long (e.g., 8 year) subsurface residence times in some basins. Dilution of N and depletion of stored N occurs in years with high discharge. Reduced N transport and increased N storage occurs in low‐discharge years. Central Iowa basins showed the greatest reduction in flow‐normalized concentrations, likely because of smaller storage volumes and shorter residence times. Effects of land‐use changes on the water quality of major Iowa Rivers may not be noticeable for years or decades in peripheral basins of Iowa, and may be obscured in the central basins where extreme flows strongly affect annual concentration trends.
Deep Drill 1972. Potassium–Argon Dating of the Bermuda Drill Core

The numerous lamprophyric sheet units which make up a substantial portion of the Bermuda Seamount appear to have been intruded about 33 m.y. ago. The pre-existing pile of tholeiitic submarine lavas may be substantially older, possibly as old as the surrounding sea floor (that is, they were formed as early as 110 m.y. ago).
Carboniferous palaeomagnetism of the Rocky Creek Block, northern Tamworth Belt, and the New England pole path

Palaeomagnetic, rock magnetic and magnetic fabric results are presented for a Carboniferous (Visean to Westphalian) succession of felsic, mainly ignimbritic, volcanic and volcaniclastic rocks from the Rocky Creek Block of the northern Tamworth Belt, southern New England Orogen. Detailed thermal demagnetisation of 734 samples from 64 sites show three groups of magnetic components with low (<300°C), intermediate (300–600°C) and high (500–680°C) unblocking temperature ranges. Well‐defined primary magnetisations have been determined for 28 sites with evidence of four overprint phases. The overprints arise from a mid‐Tertiary weathering event (or possibly recent viscous origin), and from fluid movements associated with the Late Cretaceous opening of the Tasman Sea, thrusting during the Middle Triassic main phase of the Hunter‐Bowen Orogeny, and latest Carboniferous — Early Permian formation of the Bowen‐Gunnedah‐Sydney Basin system. Rock magnetic tests establish that the primary magnetisation carriers in the volcanic rocks are mainly magnetite (predominantly single domain, or pseudo‐single domain, and little or no multidomain) and hematite. Optimal magnetic cleaning is achieved at high to very high temperatures, with subtle, but systematic, directional and statistical differences between primary components derived from the mainly hematite fraction and pseudo‐components derived from the mainly magnetite fraction. The 28 primary magnetisation results are presented as six mean‐site results, summarised below and representing 25 sites, and three single‐site results. Fold tests could be applied to five mean‐site results. These are all positive, but one of these results may represent a secondary magnetisation. The primary magnetisation results define a Visean to Westphalian pole path. This long pole path indi cates extensive latitudinal and rotational movement for the Rocky Creek Block, and potentially for the New England Orogen, as follows: (i) Yuendoo Rhyolite Member (Caroda Formation, Visean) pole 235.8°E, 27.7°S, ED95 = 9.0°, n = 3; (ii) Peri Rhyolite Member/Boomi Rhyolite Member (Clifden Formation, Namurian, 318.0 ± 3.4 Ma) pole 177.4°E, 63.4°S, ED95 = 5.2°, n = 3; (iii) tuffaceous beds above Boomi Rhyolite Member (Clifden Formation? , Namurian) pole 162.2°E, 59.1°S, ED95 = 10.2°, n = 3; ((iv) upper Clifden Formation/lower Rocky Creek Conglomerate (Namurian/Westphalian) pole 95.3°E, 49.6°S, ED95 = 8.1°, n = 3 (possible overprint)); (v) Rocky Creek Conglomerate (Westphalian) pole 136.5°E, 57.6°S, ED95 = 5.3°, n = 5; (vi) Lark Hill Formation (Westphalian) pole 127.0°E, 50.4°S, ED95 = 4.8°, n = 8.
MIGRATION AND AGEING OF THE POPULATION OF THE CZECH REPUBLIC AND THE EU COUNTRIES

The population ageing is the main population problem of Europe. Population development may influence the economy and the economy may retrospectively influence population development. The consequences of this process may appear with a delay of several decades and they may have an unfavourable influence on the functioning of the economy and the prosperity of individual European countries. In connection with this, the international migration is often brought up, mainly the question whether the migration can solve or at least lessen the ramifi cations connected with the decrease in the number of population itself and population ageing. The migration itself is rather wide and extensive and cannot be dwelled upon in great detail, ergo we pointed out some of the ground ideas in this article, especially those which are most commonly connected with the demographic migration.
Effects of Dietary Protein Levels on Fecal Amino Acids Excretion and Apparent Digestibility, and Fecal and Ileal Microbial Amino Acids Composition in Weaned Piglets

Background and Aims: The purpose of this study was to determine the effects of low protein diets with the same Lys, Met + Cys, Thr, and Trp levels as in high protein diets on the fecal amino acid excretion and apparent digestibility, and ileal and fecal microbial amino acids composition in weaned piglets. Methods: Fifty-four 21-day-old Duroc × Landrace × Yorkshire weaned piglets were randomly divided into three groups and fed with corn-soybean meal basal diets, in which the crude protein (CP) content was 20% (H-CP), 17% (M-CP), and 14% (L-CP), respectively. The experiment included a 7-day adaptation period and a 45-day trial period. Six piglets in each group were randomly slaughtered on days 10, 25, and 45 of the trial period, and the intestinal contents, intestinal mucosa, and feces were collected. Results: The results showed that the interaction between feeding time and dietary CP levels was reflected in the apparent digestibility of dietary CP and amino acid (AA) (p < 0.01). With the increase of age, the apparent digestibility of CP and AA were increased (p < 0.01). With the increase of CP levels, the excretion of nitrogen (N) was decreased (p < 0.01), whereas the flow of microbial AA in the ileum and feces were increased (p < 0.01). The interaction between feeding time and dietary CP levels was also reflected in the composition of AA in the ileum and stool of piglets (p < 0.01). The proportion of His, Lyr, Met, Cys, and Ser was lower than the average, whereas the proportion of Phe, Leu, Pro, Ala, Glu, and Asp was higher than the average. With the increase of age, the AA content of microorganisms increased (p < 0.01). Conclusion: All in all, this work revealed the changes of N, CP, and AA excretion and digestibility of feces and microorganisms of piglets under the combined action of different dietary protein levels and different feeding times, and also the changes of AA composition of intestinal microorganisms and AA composition of microorganisms.
Mauna Loa lava accumulation rates at the Hilo drill site: Formation of lava deltas during a period of declining overall volcanic growth

Accumulation rates for lava flows erupted from Mauna Loa, as sampled in the uppermost 280 m of the Hilo drill hole, vary widely for short time intervals (several thousand years), but overall are broadly similar to those documented elsewhere on this volcano since 100 ka. Thickness variations and accumulation rates for Mauna Loa lavas at the Hilo drill site have been strongly affected by local paleotopography, including funneling and ponding between Mauna Kea and Kilauea. In addition, gentle submerged slopes of Mauna Kea in Hilo Bay have permitted large shoreline displacements by Mauna Loa flows. Ages of eruptive intervals have been determined from published isotopic data and from eustatic sea level curves modified to include the isostatic subsidence of the island of Hawaii at 2.2–2.6 mm/yr. Prior to 10 ka, rates of Mauna Loa lava accumulation at the drill site varied from 0.6 to 4.3 mm/yr for dateable intervals, with an overall rate of 1.8 mm/yr. Major eruptive pulses at about 1.3 and 10 ka, each probably representing a single long-lived eruption based on lack of weathering between flow units, increase the overall accumulation rate to 2.4 mm/yr. The higher rate since 10 ka reflects construction of thick near-shoreline lava deltas as postglacial sea levels rose rapidly. Large lava deltas form only along coastal segments where initially subaerial slopes have been submerged by the combined effects of eustatic sea level rise, isostatic subsidence, or spreading of volcano flanks. Overall accumulation of 239 m of lava at the drill site since 100–120 ka closely balances submergence of the Hilo area, suggesting that processes of coastal lava deposition have been modulated by rise in sea level. The Hilo accumulation rate is slightly higher than average rates of 1–2 mm/yr determined elsewhere along the Mauna Loa coast, based on rates of shoreline coverage and dated sea cliff and fault scarp exposures. Low rates of coastal lava accumulation since 100 ka, near or below the rate of island-wide isostatic subsidence, indicate that Mauna Loa is no longer growing vigorously or even maintaining its size above sea level.
Aggregate‐Protected and Unprotected Organic Matter Pools in Conventional‐ and No‐Tillage Soils

No-tillage (NT) practices can result in greater soil aggregation and higher soil organic matter (SOM) levels than conventional-tillage (CT) practices, but the mechanisms for these effects are poorly known. Our objectives were to describe the size and quality of biologically active pools of aggregate-associated SOM in long-term CT and NT soils of the southeastern USA. Samples were collected from replicated CT and NT plots on a Hiwassee sandy clay loam (clayey, kaolinitic, thermic Rhodic Kanhapludult) and separated into four aggregate size classes (>2000, 250-2000, 106-250, 53-106 m) by wet sieving. Potentially mineralizable C and N and N2O emissions were measured from 20-d laboratory incubations of intact and crushed macroaggregates (>250 m) and intact microaggregates (<250 m). Three primary pools of aggregate-associated SOM were quantified: unprotected, protected, and resistant C and N. Aggregate-unprotected pools of SOM were 21 to 65% higher in surface soils of NT than of CT, with greater differences in the macroaggregate size classes. Disruption of macroaggregates increased the mineralization of SOM in NT but had little effect in CT. Rates of mineralization from protected and unprotected pools of C were higher in surface soils of CT than of NT. Macroaggregateprotected SOM accounted for 18.8 and 19.1% of the total mineralizable C and N (0-15 cm), respectively, in NT but only 10.2 and 5.4% of the total mineralizable C and N in CT. Our results indicate that macroaggregates in NT soils provide an important mechanism for the protection of SOM that may otherwise be mineralized under CT practices.
Controls on δ18O and δ13C profiles within the aragonite bivalve Arctica islandica

The geochemistry of Arctica islandica shells provides an opportunity to reconstruct intra-annual resolution climate records in temperate latitudes, and the annual banding allows close temporal constraint. Stable isotope analyses of carbon and oxygen from an Arctica islandica live-collected at 6 m depth from Irvine Bay, UK are presented. Seawater temperature ranges reconstructed from shell δ18O agree, within error, with instrumental sea surface temperature measurements. The saw-tooth profile of the seasonal δ 18O signal (compared with the sinusoidal seawater temperature) indicates that shell accretion rate is not constant throughout the year. Modelling the expected δ18O profile from water temperature, salinity and shell growth rate suggest that A. islandica at this site has significant variation in the shell extension rate during the year. Material deposited during shell damage shows a positive shift in δ18O. A strong ontogenetic effect is seen in δ13C and damage to the shell is associated with a significant (>0.5‰) and sustained shift of δ 13C.
Measuring velocity dispersion and attenuation in the exploration seismic frequency band

No perfectly elastic medium exists in the earth. In an anelastic medium, seismic waves are distorted by attenuation and velocity dispersion. Velocity dispersion depends on the petrophysical properties of reservoir rocks, such as porosity, fractures, fluid mobility, and the scale of heterogeneities. However, velocity dispersion usually is neglected in seismic data processing partly because of the insufficiency of observations in the exploration seismic frequency band (∼5 through 200 Hz ). The feasibility of determining velocity dispersion in this band is investigated. Four methods are used in measuring velocity dispersion from uncorrelated vibrator vertical seismic profile (VSP) data: the moving window crosscorrelation (MWCC) method, instantaneous phase method, time-frequency spectral decomposition method, and cross-spectrum method. The MWCC method is a new method that is satisfactorily robust, accurate, and efficient in measuring the frequency-dependent traveltime in uncorrelated vibrator records. The MWC.
Anthropogenic influence on the changing likelihood of an exceptionally warm summer in Texas, 2011

The impact of anthropogenic forcing on the probability of high mean summer temperatures being exceeded in Texas in the year 2011 was investigated using an atmospheric circulation model to simulate large ensembles of the world with 2011 level forcing and 5 “counterfactual” worlds under preindustrial forcing. In Texas, drought is a strong control on summer temperature, so an increased frequency in large precipitation deficits and/or soil moisture deficits that may result from anthropogenic forcing could magnify the regional footprint of global warming. However, no simulated increase in the frequency of large precipitation deficits, or of soil moisture deficits, was detected from preindustrial to year 2011 conditions. Despite the lack of enhancement to warming via these potential changes in the hydrological cycle, the likelihood of a given unusually high summer temperature being exceeded was simulated to be about 10 times greater due to anthropogenic emissions.
High-Pressure Isotropic Compression Tests on Fiber-Reinforced Cemented Sand

High-pressure isotropic compression tests were carried out on reconstituted sand samples that were reinforced with cement, randomly distributed fibers, or both, making comparisons with the unreinforced sand and conducting tests from a variety of initial specific volumes. The results indicated changes in the isotropic compression behavior of the sand due to the inclusion of fibers and/or cement. Cementitious bonds are sufficiently strong relative to the particles to allow the cemented samples to reach states outside the normal compression line NCL of the uncemented soil, but the effectiveness of cemented fiber-reinforced specimens is even larger due to the control of crack propagation in the cemented sand after the inclusion of fibers. Distinct NCLs were observed for the sand, fiber-reinforced sand, cemented sand, and fiber-reinforced cemented sand. Both fiber breakage and fiber extension were observed in fibers measured after testing indicating that fibers individually have worked under tension, even though in the macroscopic scale, isotropic compressive stresses were applied. Fiber reinforcement was found to reduce the particle breakage of both the uncemented and cemented sands.
Endogenous zebrafish proneural Cre drivers generated by CRISPR/Cas9 short homology directed targeted integration

The Cre/lox recombinase system has been widely used for spatiotemporal control of gene expression in animal model systems, however, efficient methods to isolate zebrafish Cre drivers that reliably recapitulate endogenous gene expression patterns are needed. Here, we apply CRISPR/Cas9 targeting to integrate a 2A-Cre recombinase transgene with 48bp homology arms into proneural genes ascl1b, olig2 and neurod1. We observed high rates of germline transmission ranging from 10%-100% (2/20 olig2; 1/5 neurod1; 3/3 ascl1b). The transgenic lines Tg(ascl1b-2A-Cre)is75, Tg(olig2-2A-Cre)is76, and Tg(neurod1-2A-Cre)is77 expressed functional Cre recombinase in the expected proneural cell populations. The results demonstrate Cre recombinase expression is driven by the native promoter and regulatory elements of the targeted genes. This approach provides a straightforward, efficient, and cost-effective method to generate cell type specific zebrafish Cre drivers whose spatial and temporal restricted expression mimics endogenous genes, surmounting the challenges associated with promoter BAC cloning and transposon mediated transgenesis.
Depositional and geotectonic history of the Gala area, eastern Southern Uplands, Scotland

Abstract The Ordovician and Silurian successions between Falahill and Galashiels encompass six flysch-dominated formations: the Upper Ordovician Portpatrick and Shinnel Formations representing the Leadhills Group, the Llandovery Mindork, Garheugh, and Buckholm Formations together comprising the Gala Group, and a formation indeterminate of age within the Hawick Group. Southward ensialic andesitic volcanic arc and northward low- to medium-grade sialic sources contributed sediment, whilst ophiolitic and subduction-related sources made minor contributions. Deposition took place firstly, in a SE-migrating back-arc basin bordering the northerly source, the Laurentian continent. Subsequent NW-directed underthrusting led to formation out of the back-arc basin of an imbricate thrust stack which migrated southeastwards. Ultimately a foreland successor basin formed ahead of the rising thrust stack. Flysch units are typically associated with linear outcrops of Moffat Shales which are the loci of major steep SE-translating reverse faults, two of which participate in a late-stage sinistral strike–slip duplex with large-scale imbrication. The faults divide the succession into a sequence of tectonostratigraphic blocks, successively younger to the SE. At least six of the ten blocks customarily recognised in the Southern Uplands, Blocks 3–8, are represented, some of which coincide with single or complete formations.