Miracle-dz/UniFAR-FTUs huggingface dataset:
Innate Immunity and CKD: Is There a Significant Association?

Chronic kidney disease (CKD) constitutes a worldwide epidemic, affecting approximately 10% of the global population, and imposes significant medical, psychological, and financial burdens on society. Individuals with CKD often face elevated morbidity and mortality rates, mainly due to premature cardiovascular events. Chronic inflammation has been shown to play a significant role in the progression of CKD, as well as in the acceleration of CKD-related complications, including atherosclerosis, cardiovascular disease (CVD), protein–energy wasting, and the aging process. Over the past two decades, a substantial body of evidence has emerged, identifying chronic inflammation as a central element of the uremic phenotype. Chronic inflammation has been shown to play a significant role in the progression of CKD, as well as in the acceleration of CKD-related complications in dialysis patients, including atherosclerosis, CVD, protein–energy wasting, and the aging process. Remarkably, chronic inflammation also impacts patients with CKD who have not yet required renal replacement therapy. While extensive research has been conducted on the involvement of both the adaptive and innate immune systems in the pathogenesis of CKD-related complications, this wealth of data has not yet yielded well-established, effective treatments to counteract this ongoing pathological process. In the following review, we will examine the established components of the innate immune system known to be activated in CKD and provide an overview of the current therapeutic approaches designed to mitigate CKD-related chronic inflammation.
Optimization of a Do-It-Yourself Air Cleaner Design to Reduce Residential Air Pollution Exposure for a Community Experiencing Environmental Injustices

The large-scale deployment of Do-it-yourself (DIY) air cleaners, especially in communities that historically bear the brunt of air pollution exposure-related injustices, provides communities a cost-effective option to reduce personal indoor exposure to particulate matter. In this study, we developed nine air cleaner prototypes, altering filter depth and the number and type of filters, and compared their PM2.5 removal effectiveness and maintenance-related parameters prior to deployment in North Denver, Colorado homes. Prototypes containing multiple high efficiency particulate air filters with a minimum reporting value of 13 (MERV13) had higher clean air delivery rates (CADR, >300 m3 h−1) compared to prototypes using a single filter (100–200 m3 h−1), but single-filter designs had comparable values of CADR normalized by initial and annual operating costs. Based on performance, cost, build time, and feedback from the community regarding concerns related to volatile organic compound exposure, the selected prototype (P9) used a combination of an activated carbon filter and single MERV13 filter with a 10.16 cm (4-inch) depth. Following this assessment, 120 of the selected air cleaner prototypes were built and deployed in homes around the communities in North Denver for two separate cohorts; feedback regarding their usage over the course of the deployment showed that in addition to the increased noise levels perceived by the participants, factors such as cold air flow from the air cleaner impacting the thermal comfort and aesthetics of the design reduced their usage time in homes. Future designs of DIY air cleaners could incorporate this feedback to help design improved features such as quieter air cleaners and real-time pollutant monitoring feedback to prompt users to keep them operational at all times of the day.
The Relationships Between State Higher Education Funding Strategies and College Access and Success

We compiled the first longitudinal data set with detailed state funding information to examine whether different funding strategies for public higher education correlate with college access and completion, with a focus on outcomes among racially minoritized students. We found no relationships between funding mechanisms and student outcomes at public universities. However, at community colleges, we found that funding strategies that combine base adjustments and enrollment or performance components may increase enrollment, but not completions.
Moisture Flow through Municipal Solid Waste: Patterns and Characteristics

Vertical moisture flow through compacted municipal waste layers is more complex than the one-dimensional, uniform Darcian drainage flow through a constant homogeneous medium as modeled in HELP. Channeling and flow along wetting curves produce irregular and more rapid breakthrough times and leakage rates. Tests of compacted municipal waste show distinct chan­ neled flow in two to three streams in cylindrical cells. Furthermore, practical field capacity is substantially lower at 0.136 than the HELP default value of 0.292. Porosity, while similar to the default value of 0.52, varies with com­ paction ratio from 0.58 to 0.47. As a result, practical unsaturated hydraulic conductivities are 10 to 10 higher at 1.2 · 10" to 1.7 · 10" cm/s than the HELP default of 1.2 · 10" cm/s. As a result, waste default values should be revised in current models, while new leachate generation models need to account for channeled flow. •This research was funded through a grant from the Natural Science and Engineering Research Council (NSERC) of Canada and through a research contract from the Alberta Special Waste Manage­ ment Corporation. This funding is gratefully acknowledged. The research was further made possible by gracious in-kind support by management and staff at the West Edmonton Landfill of Waste Manage­ ment Inc. of Edmonton. Finally, the effort and tenacity of J. Zou and K. Knynsberg as well as the word processing expertise of D. Salvian are sincerely appreciated. The comments in this article are for information and discussion purposes only and are not to be relied upon in any particular situation without the expressed written consent of the authors. 211 © 1994, Baywood Publishing Co., Inc. doi: 10.2190/KBUD-RFHT-JYHP-A35E http://baywood.com 212 / ZEISS AND MAJOR
Geologic Characteristics and the Genesis of the Wulagen Lead-zinc Deposit,Xinjiang,China

Wulagen lead-zinc deposit is located in the northern part of the southwest depression of Tarim basin,Wuchia County,Xinjiang.It is considered as a sandstone-hosted type deposit with the proved and prospective Pb-Zn reserves 10 Mt(Pb-Zn of 3.62%). The layered orebodies more than 3km long and 10~50m wide occur between the Lower Cretaceous Kizilsu Group(K1kz)of the red sandstone and the thick gyprocks of Paleocene Aertashi Formation.It's grey in color,mainly due to decolored alteration and mineralization of red sandstones,which overlies widely K1kz in the north of the depression,and 140km in length and 100~300m in width.The hangingwall of the ore is breccias rock resulting from collapsed dissolving gyprocks.The light brown sphalerite,galena,minor marcasite,pyrite and chalcopyrite are very fine or colloid structure contaminated in the cement of the sandstone.Minor coarse-grained galena occurs in vein.The gangue minerals include calcite,dolomite and some sericite,etc.There are a lot of asphalt and organic matter in the fluid inclusion in the lead-zinc ore,which shows that the migration and precipitation of lead and zinc is related closely to that of oil and gas.The lead-zinc deposit is result of regional migration of the basin brine when the Tarim basin was separated from paleo-Mediterranean during early Himalayan movement,in Oligocene-Miocene.The lead and zinc of the deposit precipitated from the basin brine,while the sulfur of the ore was likely derived from the bacteria reduction of sulfate from the dissolving gyprock of the hangwall.The genesis of the deposit belongs to epithermal type related to basin brine.
Probiotics in Postoperative Pain Management

Postoperative pain is the unpleasant sensory and emotional experience after surgery, its origin being both the inflammatory reaction induced by the surgical trauma on the abdominal wall and the splanchnic pain induced by the activation of nociceptors of the viscera, which are highly sensitive to distension, ischemia, and inflammation. Nowadays, it is well recognized that there is a close relationship between the gut microbiome and pain perception, and that microbiome is highly affected by both anesthesia and surgical manipulation. Thus, efforts to restore the disturbed microbiome via supplementation with beneficial bacteria, namely probiotics, seem to be effective. In this article, the knowledge gained mainly from experimental research on this topic is analyzed, the concluding message being that each probiotic strain works in its own way towards pain relief.
Horizontal and Vertical Comparison of Microbial Community Structures in a Low Permeability Reservoir at the Local Scale

Petroleum microorganisms play a crucial role in the application of microbial-enhanced oil recovery, and the community structures of petroleum microorganisms have been widely studied. Due to variations in reservoir geological conditions, reservoir microbial communities exhibit unique characteristics. However, previous studies have primarily focused on microbial community changes within a single well, a single block, and before and after water flooding, and thus, cross-horizon and cross-regional comparative studies of in situ microbial communities are lacking. In this study, the 16S rRNA full-length sequencing method was adopted to study bacterial communities in crude oil samples taken from two wells at the same depths (depths of 2425 m and 2412 m) but approximately 20 km apart in the Hujianshan oilfield, located in the Ordos Basin. At the same time, the results were combined with another layer of research data from another article (from a depth of 2140 m). The aim was to compare the differences in the microbial community structures between the oil wells on a horizontal scale and a vertical scale. The results revealed that there were minimal differences in the microbial community structures that were influenced by the horizontal distances within a small range (<20 km), while differences were observed at a larger spatial scale. However, the dominant bacteria (Proteobacteria and Bacteroidetes) in the different oilfields were similar. Vertical depth variations (>300 m) had significant impacts on the communities, and this was mainly controlled by temperature. The greater the depth, the higher formation temperature, leading to an increase in thermophilic and anaerobic bacteria within a community.
Functionalization of MWCNTs for Bioelectrocatalysis by Bacterial Two-Domain Laccase from Catenuloplanes japonicus

This study was carried out in order to assess several modifications of carbon nanotube-based nanomaterials for their applications in laccase electrodes and model biofuel cells. The modified MWCNTs served as adapters for the immobilization of laccase from Catenuloplanes japonicus VKM Ac-875 on the surface of electrodes made of graphite rods and graphite paste. The electrochemical properties of the electrodes were tested in linear and cyclic voltammetrical measurements for the determination of the redox potential of the enzyme and achievable current densities. The redox potential of the enzyme was above 500 mV versus NHE, while the highest current densities reached hundreds of µA/cm2. Model biofuel cells on the base of the laccase cathodes had maximal power values from 0.4 to 2 µW. The possibility of practical application of such BFCs was discussed.
Health Disparities in Cognitive Impairment and Dementia: Role of Social Strain, Depression, and C-Reactive Protein

We investigated the association of social strain from friends, depression, and systemic inflammation (C-Reactive Protein [CRP]) with cognitive impairment without dementia (CIND) and dementia among 9,262 participants (age ≥ 65). We analyzed data from the Health Retirement Study (HRS), performing Chi-squared and logistic regression analyses. Measures included the 27-point HRS cognition scale, social strain scale, Center for Epidemiological Studies Depression scale, and dried-blood CRP levels. Black and Hispanic participants had a significantly increased dementia risk (OR = 2.69 and OR = 2.54). Black participants also had a high risk of CIND (OR = 2.80), but no association of Hispanic participants with CIND. Increased social strain from friends and depression were significantly associated with CIND (OR = 1.50 and OR = 1.44) and dementia (OR = 1.57 and OR = 1.78). Elevated CRP levels were only linked to CIND risk (OR = 1.03), not dementia. Early detection and interventions targeting social strain, depression, and CRP levels may help promote cognitive functioning in older adults.
A RIF Based Mapping of RDB2RDF

Mapping RDB to RDF (i.e., RDB2RDF) is the key to constructing the Semantic Web, hence has been an active research field during the last decade. Many technically heterogeneous RDB2RDF tools resulted in non-interchangeable and unreusable RDB2RDF mapping descriptions. In 2009, the W3C RDB2RDF Incubator Group Report once strongly suggested that the RDB2RDF mapping language be expressed in rules as defined by the W3C Rule Interchange Format (RIF) Working Group, because rules are an effective way to express mappings between information models, and RIF, as part of the infrastructure for the Semantic Web, is now a standard for exchanging rules among Web rule systems. This paper addresses the issue of RIF-based RDB2RDF mapping and proposes a database semantics-driven, RIF Production Rule Dialect (RIF-PRD) based mapping description approach. The work includes defining a set of generic RIF-PRD mapping rules for RDB2RDF, developing a prototype mapping engine called RIFD2RME (stands for RIF-based RDB2RDF Mapping Engine), and conducting case study experiments with the prototype. The experimental results indicate that the proposed mapping approach is achievable and effective.
Association between Myeloperoxidase Enzyme Levels in Parenchymal Lung Disease and Airway Disease in Paediatrics

Background: The most prevalent pro-inflammatory biomarker found in neutrophilic granulocytes is myeloperoxidase enzyme. In order to fight various microbial activities, proinflammatory factors and oxidative stress at the infection site release it from these cells. Several reactive oxygen and nitrogen species are produced as a result of MPO's antimicrobial actions. Aim and objectives: This study aimed to assess the diagnostic value of myeloperoxidase elevation in parenchymal lung disease and airway disease in children. Subjects and methods: This cross-sectional investigation was carried out at the Pediatrics Department of the Suez Canal University Hospitals Faculty of Medicine. 99 patients were split into 3 groups: Group A had 33 patients with pneumonia, group B had 33 patients with bronchiolitis and group C had 33 patients with bronchial asthma in addition to 33 healthy cases as control group. Results: Serum and salivary MPO levels were reliable in the diagnosis of pneumonia, but only serum MPO level can be used to diagnose patients with asthma. However, serum and salivary MPO levels failed to diagnose patients with bronchiolitis. Also, salivary MPO failed to diagnose patients with asthma. Moreover, serum and salivary MPO levels failed to predict outcome among pneumonia, bronchiolitis and asthma patients. Conclusion: Both serum and salivary myeloperoxidase levels were significantly differed between pneumonia, bronchiolitis, bronchial asthma and control groups, suggesting the potential role of MPO in the diagnosis of parenchymal lung disease and airway disease in pediatrics
Distributed Robust Containment Control for Multi-Robot Systems via Adaptive Critic Designs

This article develops a distributed robust containment control approach for multi-robot systems via adaptive critic designs. To begin with, the distributed robust containment control problem of multi-robot systems with modeling uncertainties is transformed into an optimal containment control problem of its nominal plant by designing discounted value functions for all following robots. Hereafter, the distributed optimal containment control law is derived by solving the coupled Hamilton-Jacobi-Bellman equation of each following robot via the critic-only structure. Moreover, theoretical analysis shows that the developed adaptive critic design-based distributed robust containment control scheme guarantees the containment errors of all following robots to be asymptotically stable. Finally, the effectiveness of the present control approach is verified by simulation studies.
Persististrombus latus-Bearing Deposits South of Isola di Capo Rizzuto, Calabria (Southern Italy)

Bracchi V.A. , Nalin R. & Basso D. , Persististrombus latus-bearing deposits south of Isola di Capo Rizzuto, Calabria (Southern Italy). (IT ISSN 0349-3356, 2011) During a research fieldtrip in the Crotone peninsula an area characterized by a flight of well developed Pleistocene marine terraces a level rich of in situ Persististrombus latus GMELIN 1791 (= Strombus bubonius LAMARCK 1822) has been discovered in a quarry south of Isola di Capo Rizzuto (Calabria, southern Italy) at ~ 46 m above sea level. P. latus is a shallow warm-water marine gastropod belonging to the Strombidae family. Presently, it lives along the tropical coasts of Africa but entered the Mediterranean through the Gibraltar Strait in the late Pleistocene as part of the socalled Senegalese fauna. P. latus found as fossil in the Mediterranean is commonly considered a marker of Marine Isotope Stage (MIS) 5.5. This is the first documented record of a level containing multiple specimens of in situ P. latus in the Crotone terraces, allowing direct correlation to the Tyrrhenian Stage or MIS 5.5. The bio-calcarenite and associated P. latus specimens have been collected in order to petrographically analyze the sediment and describe the benthic association. RIASSUNTO: Bracchi V.A. , Nalin R. & Basso D. , Persististrombus latus in depositi di terrazzo marino a sud di Isola di Capo Rizzuto, Calabria (Italia). (IT ISSN 0349-3356, 2011) Durante una campagna di ricerca nella penisola di Crotone, area caratterizzata dalla presenza di terrazzi marini ben sviluppati, è stato rinvenuto un livello ricco di Persististrombus latus GMELIN 1791(= Strombus bubonius LAMARCK 1822) in situ, in una cava posta a sud di Isola di Capo Rizzuto (Calabria, Italia) a circa 46 m di altitudine. P. latus è un gasteropode di acque calde e poco profonde della famiglia Strombidae. E’ tuttora vivente lungo le coste tropicali africane, ma si introdusse nel Mar Mediterraneo attraverso lo Stretto di Gibilterra nel tardo Pleistocene, come membro della fauna detta Senegalese. P. latus viene comunemente considerato un marker dello Stadio Isotopico Marino (MIS) 5.5. Questo è il primo ritrovamento documentato di un livello contenente molteplici esemplari in situ di P. latus nell’area dei terrazzi crotonesi, permettendo una correlazione diretta con lo Stadio Tirreniano o MIS 5.5. La bio-calcarenite associata ed esemplari di P. latus sono stati campionati al fine di analizzare petrograficamente il sedimento e descrivere l’associazione bentica.
REPARATIVE EFFECT OF MELATONIN ON THE MANDIBULAR ALVEOLAR BONE AND GINGIVA OF RATS WITH INDUCED PERIODONTITIS

BACKGROUND: Periodontitis is a chronic inflammatory disease marked by intricate interactions between periodonto-pathogenic bacteria and the host’s immunity. It has a complicated etiology including bacterial colonization, excessive inflammation, and increased oxidative stress. Due to its antioxidant properties, stimulation of fibroblast proliferation, anti-inflammatory capacity, and bone remodeling capability; melatonin can contribute to ameliorating chronic conditions and can have potential dental applications such as in periodontal disease. AIM
Effects of Dewdrop on Plastic Films on Light Transmittance, Temperature and Humidity in Greenhouses

Light transmittance, temperature and humidity of greenhouses covered with three PolyOlefin films of PO1 (Mikado Chemical M.F.G. Co., Super solar 0.15mm in thickness), PO2 (Sumitomo Chemical Co., Cleantate-LF, 0.15mm in thickness), and PO3 (Mikado Chemical M.F.G., Co., U-lack, 0.1mm in thickness), and a ploy vinyl chloride film PVC (Mitsubishi Chemical MKV Co., Clean Ace-CPM, 0.13mm in thickness) were examined to elucidate the differences of microclimate inside the greenhouses. All the films were covered in October 1993 except PO3 which was covered in October 1994. Several kinds of vegetables such as spinach, daikon-radish, Chinese-cabbage and red-radish were cultivated under usual management in each autumn-winter-spring season. Air temperature, humidity, solar rediation, and soil heat flux inside and outside (control) each greenhouse were measured during every winter-spring season. Dewdrop and/or condensation water on the covering film and the water content in the air were measured in order to check the humidity conditions in each greenhouse. The relationship between light transmittance and the dewdrop on films of the greenhouses was analyzed using the data obtained mainly in 1995-1996 season and 1997. The main results are as follows.1. Transmittance of solar radiation of PO1, PO2, PO3-greenhouses was 76.7%, 79.7%, and 63.5%, respectively, while that of the PVC-greenhouse was 71.6% at early March in 1996.2. Ventilation rate of PO1 and PO2-greenhouses was high but that of PVC was very low. The differences in ventilation rate were caused by different draft condition of each greenhouse.3. As compared to other three greenhouses, air temperature difference between the inside and outside of the PO3-greenhouse was lower by 2-4°C during daytime, resulting from the heavy dewing on the covering film.4. Average dewdrop on the films of the PVC and PO3-greenhouses was from 140-250g/m2 on cloudy day, while that of the PO1 and PO2-greenhouses was less than 40g/m2. Dewing on the greenhouse films reduced the transmittance of the solar rariation at a rate of exp (-0.9d), where d is equivalent water film thickness of dewdrop and/or condensation.5. An empirical equation was obtained using the relationship between light transmittance and the dewdrop thickness in order to estimate the air temperature difference between the inside and outside of greenhouse. Estimated values agreed well with measured values, suggesting that the effect of the dewdrop on the heat budget of the greenhouse can be quantified accurately.6. High level of dewdrop was caused by a lack of the drip control performance (runoff function) of films which decreased light transmittance, thereby increasing humidity and decreasing air temperature inside greenhouses.