Miracle-dz/UniFAR-FTUs huggingface dataset:
Microbiological Result of the High Vaginal Swab in a Patient with Preterm Premature Rupture of the Membranes (PPROM) Versus Preterm Labor (PTL)

The complications of preterm birth cause approximately 70% of neonatal deaths and nearly half of all long-term neurological morbidity. In this study, we aim to report the findings of the laboratory investigations for high vaginal swabs (HVS) and their relation to PTL and PPROM. We performed a prospective cohort study of women presenting at The King Fahd Hospital of the University (KFHU) in Khobar, Kingdom of Saudi Arabia, with and without risk factors for preterm birth between December 2018 and December 2019. Women aged 15 to 40 years and satisfying inclusion criteria were included in the study. Finally, we included 117 women in the current study, with a total mean age of 30.5 ± 6.3 years and overall average gestational age, at delivery, of 33.8 ± 2.8 weeks. Out of those 117 women, 114 were diagnosed with having a PTL, while the other three had a PPROM. Among the 117 included women, 69 (58.9%) did not perform HVS, and only 48 women did. The findings were variable among PPROM and PTL groups. For PPROM, all of the three patients had a normal HSV with no detected organisms or pathological findings. Out of the 45 PTL patients who had HVS, we found a normal HSV (negative findings) in 39 patients (86.7%), the presence of yeasts in five patients (11.1%) and the presence of Candida albicans in one patient (2.2%). These findings indicate the urge to develop more advanced techniques for better detection of genital infections, and prevention of its complications.
Early clinical outcomes of thoracoscopic mitral valvuloplasty: a clinical experience of 100 consecutive cases.

Background We reported our experience of 100 consecutive cases of thoracoscopic mitral valvuloplasty in the early period. Methods Between September 2017 and December 2019, 100 consecutive cases (aged 49.2±14.7 years; 56% male) of thoracoscopic mitral valvuloplasty had been completed in our institution. The safety and feasibility of this technique was evaluated by its early clinical outcomes. Results Mitral valve (MV) repair was performed by means of Carpentier techniques, including leaflet folding in 5 cases, cleft suture in 10, commissuroplasty in 15 including 2 commissurotomy, edge to edge in 1, artificial chordae implantation in 76 cases with an average of 2.5±1.6 (1 to 4) pairs, and prosthetic annuloplasty in all cases. Intraoperative transoesophageal echocardiography (TEE) revealed no mitral regurgitation (MR) in 95 cases and a mild in 2 cases with all coaptation length more than 5 mm. The rest 3 cases with moderate or more MR were successfully reconstructed during a second pump-run. The average cardiopulmonary bypass (CPB) time was 164.4±51.0 min and aortic clamping time was 119.7±39.1 min, and the latest 10 cases were 140.2±45.3 and 96.3±25.4 min, respectively (P<0.05). There was only one operative death from avulsion of left atrial suture after operation and 2 intraoperative re-exploration through a conversion to sternotomy for bleeding. Severe MR was observed in 2 patients 3 months after operation, and MV replacement (MVR) was performed through median sternotomy. Conclusions Totally thoracoscopic mitral valvuloplasty was technically feasible, safe, effective, and reproducible in clinical practice after crossing the learning curve.
Perceived Agency of a Social Norm Violating Robot

In this experiment, we investigated how a robot’s violation of several social norms inﬂuences human engagement with and perception of that robot. Each participant in our study (n = 80) played 30 rounds of rock-paper-scissors with a robot. In the three experimental conditions, the robot violated a social norm by cheating, cursing, or insulting the participant during game-play. In the control condition, the robot conducted a non-norm violating behavior by stretching its hand. During the game, we found that participants had strong emotional reactions to all three social norm violations. However, participants spoke more words to the robot only after it cheated. After the game, participants were more likely to describe the robot as an agent only if they were in the cheating condition. These results imply that while social norm violations do elicit strong immediate reactions, only cheating elicits a signiﬁcantly stronger prolonged perception of agency.
TOOTH ROOT STRESS MODIFYING FACTORS OF WEBBED GEARS

: The affect of a spur thin-rimmed gear structure upon tooth root stress has been analysed for a gear without web and with middle and offset web. To bring into line with the proposal of standard ISO, method B for tooth root stress calculation where the rim thickness factor is used for nominal stress correction of thin-rimmed gear, the ratio of tooth root stress for thin-rimmed and a solid gear, has been established based upon the 3D FEM calculations. Unlike for the case of standard ISO tooth root stress calculation, the obtained stresses have allowed the insight into the influence of actual gear structure on the tooth root stress, they have pointed to the differences between analytical 2D ISO and 3D FEM approach, and have aimed the possibilities for tooth root stress minimisation.
Provably Efficient Online Hyperparameter Optimization with Population-Based Bandits

Many of the recent triumphs in machine learning are dependent on well-tuned hyperparameters. This is particularly prominent in reinforcement learning (RL) where a small change in the configuration can lead to failure. Despite the importance of tuning hyperparameters, it remains expensive and is often done in a naive and laborious way. A recent solution to this problem is Population Based Training (PBT) which updates both weights and hyperparameters in a single training run of a population of agents. PBT has been shown to be particularly effective in RL, leading to widespread use in the field. However, PBT lacks theoretical guarantees since it relies on random heuristics to explore the hyperparameter space. This inefficiency means it typically requires vast computational resources, which is prohibitive for many small and medium sized labs. In this work, we introduce the first provably efficient PBT-style algorithm, Population-Based Bandits (PB2). PB2 uses a probabilistic model to guide the search in an efficient way, making it possible to discover high performing hyperparameter configurations with far fewer agents than typically required by PBT. We show in a series of RL experiments that PB2 is able to achieve high performance with a modest computational budget.
Violence as a Fact Accepted By Women: A Cross-Sectional Study in Sanliurfa, Turkey

1 Assistance Prof, Harran University Faculty of Health Sciences, Nursing Department, Sanliurfa, Turkey 2 Professor, Harran University Faculty of Medicine, Public Health Department, Sanliurfa, Turkey 3 Assistance Prof, Harran University Faculty of Health Sciences, Nursing Department, Sanliurfa, Turkey 4 Lecturer, Harran University Faculty of Health Sciences, Nursing Department, Sanliurfa, Turkey 5 Nurse, Institue of Health Science, Şanlıurfa 6 Assist Phy, Harran University Faculty of Medicine, Public Health Department, Sanliurfa, Turkey
Comparison of laboratory investigative methods with clinical assessment criteria for the diagnosis of bacterial vaginosis

Bacterial vaginosis (BV) is the most common cause of vaginal discharge among women of childbearing age. Its prevalence varies from 10 to 65% and is higher in sexually transmitted disease clinics. This study was carried out to compare the laboratory investigative methods with clinical assessment criteria for diagnosis of bacterial vaginosis. This prospective study included 200 vaginal swabs complaining of abnormal vaginal discharge. Amsels criteria, wet mount preparation and smears for Gram staining were prepared for Nugent criteriaAnaerobic cultures were done for isolation of anaerobic bacteria associated with BV. In results Total 128 patients showed bacterial vaginosis according to the amsel’s criteria. Gram staining for Nugent scoring was examined by two different evaluators to see inter evaluator variations. The inter observer evaluation complete agreement was shown by 90.5 % i.e. in the 181 slides with agreement on slides, both the investigators scored the same group normal, intermediate or BV. While the interpretation of slides were in disagreement only in 9.5% of cases that too between intermediate and BV group. There is no disagreement in negative cases between both the observers. So interrater reproducibility was excellent between both the observers Out of 200 cases, 176 were culture positive for anaerobes other than lactobacilli. The Gram negative anaerobes out-numbered the Gram positive ones. In conclusion the prevalence of BV in developing countries are high So with limited resources countries such as India, diagnosis of BV , there is a great need for inexpensive diagnostic methods for bacterial vaginosis.
Incidence of myocardial injury in coronavirus disease 2019 (COVID-19): a pooled analysis of 7,679 patients from 53 studies.

Background Coronavirus disease 2019 (COVID-19) has become global pandemic and resulted in considerable morbidity and mortality since December 2019. Information on the incidence of myocardial injury remains scarce. Methods English-language databases (PubMed, Embase, Cochrane), Chinese-language databases (CNKI, VIP, WANFANG), and preprint platform were searched to identify studies that reported the myocardial injury data in COVID-19 patients. Random-effects meta-analyses were used to derive the pooled incidence and relative risks (RRs) of myocardial injury. Variations by disease severity were examined by subgroup analyses. Sensitivity analyses were performed to strengthen the results. Meta-regression was applied to explore the risk factors associated with myocardial injury. Results A total of 53 studies involving 7,679 patients were included. The pooled incidence of myocardial injury was 21% [95% confidence interval (CI), 17-25%; I2, 96.5%]. The highest incidence of myocardial injury was found in non-survivors (66%; 95 CI%, 54-78%; I2, 85.7%), followed by severe patients (43%; 95 CI%, 33-53%; I2, 93.0%) and non-severe patients (11%; 95 CI%, 7-15%; I2, 95.2%). Higher risk of myocardial injury was detected in severe patients than non-severe patients (RR, 5.74; 95% CI, 3.74-8.79; I2, 86.8%). All the sensitivity analyses confirmed the robustness of primacy results. Conclusions This meta-analysis showed that myocardial injury occurred in 21% of COVID-19 patients. An elevated rate was observed in non-survivors (66%) and severe patients (43%). Severe patients had a 4.74-fold increase in the risk of myocardial injury than non-severe patients. Aggressive strategy may be considered for COVID-19 patients at high risk of myocardial injury.
Effect of Slow Deep Breathing on Blood Pressure and Heart Rate in Young Adult Male and Female Medical Students

It has been reported that there are effects of deep breathing and breath holding on the cardiovascular and blood pressure parameters. It is generally seen that BP tends to decrease during inhalation and increase during exhalation these changes may alter blood pressure measurements resulting in measured blood pressures being different. This study aims to find the effects of slow deep breathing practice on the blood pressure and Heart rate of young healthy adult male and female medical students. Methods: This study was conducted in the Department of Physiology, RVM Institute of Medical Sciences, Laxmakapally, Telangana. A total of n=50 subjects were selected randomly; the subjects were the medical students of RVM institute. Out of which (n=25) Group (M) males and (n=25) Group (F) were females. The baseline parameters of the subjects were recorded at the beginning of the study and the subjects were then trained for slow deep breathing @ 6 breaths per minute for a period of 3 months under the supervision of the investigator. Subjects are asked to take slow and maximal inspiration lasting for five seconds, followed by maximal expiration which also lasts for five seconds at a rate of 6 breaths per minute during each practice. A standard BP measurement was performed using a pneumatic cuff while listening to "Korotkoff sounds". All cardiovascular functional parameters were recorded before the trial, during breath-holding, and during recovery. Results: The values of SBP parameters in Group (M) Male before and after training were found to be significant. The DBP change in initial and final values in this group was not significant. The respiratory rates changes were also found to be significant in the Group (M). In the Group (F) no parameter was found to be changed significantly between the initial and final readings. The intergroup comparison of the parameters in the final readings shows a significant change in both SBP and DBP. Conclusion: it can be concluded that slow deep breathing for a period of 3 months decreases the blood pressure and heart rates and improves the autonomic functions. The effects are more marked in the male participants as compared to females of the same age group. The effect of slow deep breathing for long durations tends to improve the parasympathetic tone.
Bruton’s Tyrosine Kinase (BTK) Inhibitors: New Possible Good Candi- dates Against COVID-19

Claudia Baratè*1, Fabrizio Mavilia2, Edoardo Benedetti1, Gabriele Buda2, Fortunato Morabito3,4, Chiara Baldini2, Francesco Ferro2, Ilaria Puxeddu2, Antonello di Paolo2, Federica Ricci2, Mario Petrini2, Sara Galimberti2 1. Hematology, AOUP, Pisa, Italy 2. Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy 3. Biotechnology Research Unit, AO of Cosenza, Cosenza, Italy 4. Hematology and Bone Marrow Transplant Unit, Hemato-Oncology Department, Augusta Victoria Hospital, East Jerusalem, Israel *Corresponding author: Dr. Claudia Baratè, UO Hematology, AOUP, Pisa, Italy
The Impact of Innovative Practices of Performance in Universities: An Exploratory Study in Brazil

The use of new practices in educational environments has happened for some time and play a reat impact in students’ and teachers’ development and behavior. Through an indepth discussion under the light of the Brazilian reality, this article tried to evidence how these new educational practices impact on the institutional performance in higher education. This research covers a conceptual model composed by independent variables (practices of innovation on Education) and also dependent one (educational results, cost efficiency and personal satisfaction of the parties). To verify the conceptual model, the research was divided into two phases. On the first phase, we tried to identify to the light of specialized literature the innovation practices used on higher education institutions (HEI) and ways of measuring the performance of the institutions. On the second part of the study we tried to group the practices found through the cluster technique and, after that, we conducted a survey with specialists selected by technical and scientific criteria. We assessed that the impact of the practices is bigger when they are related to personal satisfaction of the participants, being followed by the educational results. Moreover, the most influent practices on institutional performance on higher education are associated to the use of Internet and mobile devices in the teaching and learning process, practices aiming to collaborative learning and pedagogical approach based on problems or projects. We conclude that this study presents relevant points and presents significant implications for educators and managers, as it may subside decision-making processes related to the implantation of new practices aiming to improve educational performance, besides pointing to new practices which can be very useful in different goals.
Measurement and modeling of lift enhancement on plunging airfoils_ A frequency response approach

A frequency response approach is taken to model unsteady aerodynamics resulting from plunging oscillations of an airfoil. The oscillations range covers high angles of attack (up to 65°) and reduced frequencies (up to 0.95) with particular attention to the range of flow nonlinearities over which lift enhancement is observed. Experiments were performed in a wind tunnel on an airfoil section at a Reynolds number of 80,000. Airfoil acceleration and lift force data were used to determine the frequency response functions between the measured unsteady lift and the quasi-steady lift. The results show enhanced lift amplitude over the stall regime at a reduced frequency of 0.7. The flow dynamics associated with this observation were identified from water tunnel experiments. Particular attention is paid to the flow separation and consequent formation and convection of the leading edge vortex. An optimization-based system identification approach is performed to represent the unsteady lift by a fourth-order dynamical system. This representation is suitable for sensitivity, dynamics and control analyses especially for applications where unsteady aerodynamics can be exploited for the purpose of lift
Endoscopic Ultrasound-Guided Liver Biopsy, Is It Ready for Prime Time?

47 We would like to further analyze several different issues that were addressed in the manuscript “The efficacy and safety of endoscopic ultrasound-guided liver biopsy versus percutaneous liver biopsy in patients with chronic liver disease: a retrospective single-center study. ” [1]. This study compared outcomes between liver biopsies performed through endoscopic ultrasound (EUS) and percutaneous routes at the University of Missouri School of Medicine from January 2018 through August 2019. The purpose of this commentary is to take an in-depth look at the following: value of liver biopsy, techniques of liver biopsy, utility of EUS guided liver biopsy, and future hold of EUS-guided liver biopsy.
HIGH PERFORMANCE HUMAN RESOURCE SYSTEM, JOB SATISFACTION AND ORGANIZATIONAL CITIZENSHIP BEHAVIOR: A MEDIATING MODEL IN VIETNAMESE CONTEXT

Empirical research on strategic human resource management indicated the positive linkage between a bundle of human resource (HR) practices and performance. However, mediating mechanisms linking human resource system and important outcomes at different levels is still open for debate. The recent years has witnessed increasingly the emphasis on the importance of organizational citizenship behavior, which is employees' behavior and actions beyond the basic requirements of the jobs. These actions are able to facilitate the employee and organizational performance. This study aims to open the socalled “black-box” by investigating the relationship between a bundle of human resource practices called high performance human resource (HPHR) system and organizational citizenship behavior in Vietnam context. This study contributes understanding mediating mechanism in HR-employee behavior relationship at the individual level. In this study, we used a system of HPHR practices including selective staffing, extensive training, internal mobility, employment security, clear job description, results-oriented appraisal, inventive reward, and participation to assess human resource practices implemented in Vietnamese firms and influence of these practices on organizational citizenship behavior. This study developed and tested a model that job satisfaction mediated the relationship between HPHR system and organizational citizenship behavior. We hypothesized that HPHR system had a positive impact on organizational citizenship behavior through job satisfaction with full mediating effect. 179 usable data collected from line managers of Vietnamese firms in Hanoi, QuangNinh and Hochiminh was used to test the research model. We discussed theoretical and practical implications of research findings and also suggested future research directions.
A Randomized Algorithm for Approximate String Matching 1

Wegivearandomizedalgorithmindeterministictime O . N log M / forestimatingthescorevector of matches between a text string of length N and a pattern string of length M , i.e., the vector obtained when the pattern is slid along the text, and the number of matches is counted for each position. A direct application is approximatestringmatching. Therandomizedalgorithmusesconvolutiontoﬁndanestimatorofthescores;thevarianceoftheestimatorisparticularlysmallforscoresthatarecloseto M , i.e., for approximate occurrences ofthepatterninthetext.Noassumptionismadeabouttheprobabilisticcharacteristicsoftheinput,oraboutthe size of the alphabet. The solution extends to string matching with classes, class complements, “never match” and “always match” symbols, to the weighted case and to higher dimensions.
The Past Climate of the Indian Region as Seen from the Modelling World

Proxy-reconstruction studies suggest several waxing and waning epochs of the Indian summer monsoon (ISM) since Last Glacial Maximum (LGM; j21 kyr BP). These fluctuations in the ISM are attributed to several internal and external factors. The few available past climate modelling studies for various epochs also support the results from the reconstruction studies for India. Our results, based on an analysis of five CMIP5-PMIP3 simulations for the periods of LGM, Mid-Holocene (MH; j6 kyr BP), last-millennium and historical period (CE 1901–1999) indicate that the ISM rainfall was lowest during the LGM, and strongest during the MH. The simulations, relative to the historical time period, suggest highest low-level convergence over the Indian region during MH and lowest during LGM. These slow changes in large-scale circulation patterns resulted in relatively highest simulated ISM rainfall during the MH, and lowest in the LGM.
Matrix remodeling and collagen disintegration in Acute Myocardial Infarction

Coronary artery diseases manifest in different forms. The pathophysiology of coronary artery diseases are complex in origin and mechanism. There are several factors involved and are contributing together for the atherosclerotic event and its complications. The plaque formation and plaque rupture are the two crucial events which may lead to acute myocardial infarction, one of the manifestations of coronary artery diseases. The matrix are involved from the very beginning of the formation of plaque via collagen formation and deposition of lipid particles in the plaque by transforming the smooth muscle cells. An equally crucial event is the plaque rupture, which occurs by the action of matrix degrading metalloproteinases on fibrous plaque leading to extracellular matrix changes subjected to thrombus formation and subsequently to infarction
Impact of mental attitude and class of complete edentulism on oral health-related quality of life of patients treated with conventional complete dentures

Aim: To assess the impact of mental attitude and class of edentulism on the oral-health related quality of life of patients treated with conventional complete dentures. Materials and method: The mental attitude and class of edentulism was assessed for 20 completely edentulous patients who were also provided with complete dentures. Their oral-health related quality of life was also assessed before treatment, 1 month and 3 months post insertion of complete dentures. Results: Majority 14 (70.0%) of the patients had a “philosophical” mental attitude while 6 patients (30%) had “exacting” attitude. Patients with Kennedy class III edentulous space had the highest mean score of 5.3 ± 0.6 (P=0.035) in the “physical function” domain while Class IV complete edentulism had the highest mean score of 7.5 ± 2.1 in the psychosocial function domain. Those with Philosophical mind had the higher base line score and post treatment scores. (p<0.05). Overall, a significant increase (P=0.0001) in the GOHAI-T mean score was observed after treatment with complete dentures irrespective of their class of edentulism or mental status. Conclusion: Class of edentulism and mental status of patients had significant impact on the oral health related quality of life of complete edentulous patients after treatment with complete dentures.