Miracle-dz/UniFAR-FTUs huggingface dataset:
Breed-typical front limb angular deformity is associated with clinical findings in three chondrodysplastic dog breeds

Angular front limb deformity (ALD) refers to an excessively curved limb conformation, which is seen in some chondrodysplastic dog breeds. Common characteristics of ALD include carpal valgus (VALG), front limb rotation (ROT), elbow incongruity, and lateral radial head subluxation. These may cause lameness and discomfort in affected dogs. The clinical impact and breed-specific characteristics of front limb conformation in chondrodysplastic breeds are unknown. This prospective and cross-sectional study aimed to investigate differences in front limb conformation between three chondrodysplastic breeds. We further evaluate whether front limb conformation is associated with clinical findings and limb function. We propose novel methods to classify findings in the interosseous space and to quantify lateral radial head subluxation. Data from a total of 224 front limbs from 112 dogs of three chondrodysplastic dog breeds (30 Standard Dachshunds, 29 Skye terriers, and 53 Glen of Imaal terriers) were included in the study. Front limb VALG and ROT were measured with a goniometer. From the radiographs, the elbow joint was graded for incongruity (INC), and the humeroradial angle (HRA) was measured to assess lateral radial subluxation. The association of front limb conformation with clinical signs and limb function was investigated using orthopedic examination, goniometric and kinetic measurements, and radiography. The breeds differed significantly in their front limb conformation. The Dachshund had the least ROT and the least radial head subluxation. The Skye terrier had the most VALG, the most radial head subluxation, and the largest prevalence of moderate and severe INC. The Glen of Imaal terrier had the most ROT. In addition, INC, ROT, VALG, and HRA were found to be independent of each other and were associated with several measurable clinical abnormalities and limb function such as pain, lameness, limited range of motion, and elbow joint osteoarthritis. This implies that VALG, ROT, and HRA could be used in addition to INC grading when choosing musculoskeletal characteristics of dogs suitable for breeding.
Effects of perioperative blood transfusion in gastric cancer patients undergoing gastrectomy: A systematic review and meta-analysis

Background The short-term and long-term effects of perioperative blood transfusion (PBT) on patients with gastric cancer are still intriguing. This systematic review and meta-analysis aimed to investigate the effects of blood transfusion on clinical outcomes in patients with gastric cancer undergoing gastrectomy. Methods We searched PubMed, Web of Science, Embase, and The Cochrane Library on December 31th 2021. The main outcomes were overall survival (OS), disease-free survival (DFS), disease-specific survival (DFS), and postoperative complications. A fixed or random-effects model was used to calculate the hazard ratio (HR) with 95% confidence intervals (CIs). Results Fifty-one studies with a total of 41,864 patients were included for this review and meta-analysis. Compared with patients who did not receive blood transfusions (NPBT), PBT was associated with worse 5-year OS (HR = 2.39 [95%CI: 2.00, 2.84]; p < 0.001; Multivariate HR = 1.43 [95%CI: 1.24, 1.63]; p < 0. 001), worse 5-year DFS (HR = 2.26 [95%CI: 1.68, 3.05]; p < 0.001; Multivariate HR = 1.45 [95%CI: 1.16, 1.82]; p < 0. 001), and worse 5-year DSS (HR = 2. 23 [95%CI: 1.35, 3.70]; p < 0.001; Multivariate HR = 1.24 [95%CI: 0.96, 1.60]; p < 0.001). Moreover, The PBT group showed a higher incidence of postoperative complications [OR = 2.30 (95%CI:1.78, 2. 97); p < 0.001] than that in the NPBT group, especially grade III-V complications, according to the Clavien-Dindo classification. [OR = 2.50 (95%CI:1.71, 3.63); p < 0.001]. Conclusion In patients who underwent gastrectomy, PBT was associated with negative survival effects (OS, DFS, DSS) and a higher incidence of perioperative complications. However, more research was expected to further explore the impact of PBT. Meanwhile, strict blood transfusion management should be implemented to minimize the use of PBT.
Development of a prognostic model to identify the metastatic nasopharyngeal carcinoma patients who may benefit from chemotherapy combination PD-1 inhibitor

Background We aimed to establish a prognostic model to identify suitable candidates for chemotherapy combination PD-1 inhibitor in metastatic nasopharyngeal carcinoma (NPC) patients. Patients and methods In this retrospective study, we included 524 patients (192 patients treated with chemotherapy combination PD-1 inhibitor and 332 received chemotherapy alone as first-line regimen) with metastatic NPC between January 2015 and March 2021. We developed a prognostic model to predict progression-free survival (PFS). A model-based trees approach was applied to estimate stratified treatment effects using prognostic scores and two well-matched risk groups (low-risk and high-risk) were created using propensity score matching. Results A prognostic nomogram was established with good accuracy for predicting PFS (c-index values of 0.71; 95% confidence interval, 0.66-0.73). The survival curves were significantly different between low-risk and high-risk groups (median PFS: 9.8 vs. 22.8 months, P < 0.001, respectively). After propensity matching analysis, chemotherapy combination PD-1 inhibitor was significantly associated with superior PFS as compared with chemotherapy alone (median PFS, 10.6 versus 9.3 months, P = 0.016) in the high-risk group. However, no significant difference between chemotherapy combination PD-1 inhibitor and chemotherapy was observed (P = 0.840) in the low-risk groups. Conclusions Our novel prognostic model was able to stratify patients with metastatic NPC into low-risk or high-risk groups and identify candidates for PD-1 inhibitor therapy. These results are expected to be confirmed by a prospective clinical trial.
Redefining resilience: The case of small entrepreneurs in Saudi Arabia

The survival of enterprises and the effective management of daily problems and obstacles, particularly those faced by small entrepreneurs, depend heavily on resilience. This study examines the critical elements that help small Saudi entrepreneurs strengthen their entrepreneurial resilience through internal locus of control and entrepreneurial self-efficacy, particularly during trying times. The partial least squares structural equation modeling (PLS–SEM) technique was used to analyse the responses of 207 small entrepreneurs operating in various regions of Saudi Arabia. The convenience sampling technique was used, and the data was collected using an online questionnaire. The study found a strong relationship between entrepreneurial resilience, internal locus of control, and entrepreneurial self-efficacy. These results demonstrated that entrepreneurial self-efficacy could mediate the relationship between the internal locus of control and entrepreneurial resilience. Finally, the study addressed limitations and provided recommendations for policymakers and potential authors.
Residual effect of varying levels of sulphur, zinc and boron on yield, yield attributing characters, nutrient uptake and quality in mustard (Brassica juncea L.) grown after cluster bean in a Mollisol

A field experiment was conducted at G.B. P.U. A.T, Pantnagar, to study the residual effect of varying levels of sulphur, zinc and boron in mustard grown after cluster bean crop in a Mollisol. The experiment was conducted with 13 treatments comprising of soil as well as foliar application. The highest seed yield (1.74 t ha-1 ) and stover yield (5.25 t ha-1 ) were recorded from 40 kg and 60 S ha-1 , respectively. The highest total B uptake (91.48 g ha-1was observed under 1.5 kg B ha-1 . The highest total Zn uptake by the pods (86.07 g ha-1 ) was observed under combined foliar applications of 0.25% Zn and 0.20% borax. However, the highest total S uptake (35.43 kg ha-1 was observed under 60 kg S ha-1 . It was concluded that with application of 4 kg Zn ha-1 , 1.5 kg B ha-1 , and 40 kg S ha-1 , a better yield of the mustard and B, Zn, and S absorption can be attained.
University of Birmingham Intestinal CD103CD11b cDC2 Conventional Dendritic Cells Are Required for Primary CD4 T and B Cell Responses to Soluble Flagellin

induction of Th2-associated responses. CD11c-cre.Irf4 ﬂ / ﬂ mice showed a reduced primary FliC-speciﬁc Th2-associated IgG1 responses, but enhanced Th1-associated IgG2c responses. These data expand our current understanding of the mucosal immune responses promoted by sFliC and highlights the potential of this adjuvant for vaccine usage by taking advantage of the functionality of mucosal CD103 + CD11b + cDC2.
Matrix-weighted Besov spaces and conditions of A_p type for 0 less than p \leq 1

We introduce the matrix weight class Ap for 0 < p < 1. For W ∈ Ap, we define the continuous and discrete matrix-weighted Besov spaces B αq p (W) and b αq p (W) and show their equivalence via transforms of wavelet type. We show that appropriate Calderon-Zygmund operators are bounded on B αq p (W). Furthermore, we determine the duals of these Besov spaces using the technique of reducing operators.
Serosurveillance on Japanese encephalitis virus in chickens collected from two different geographical areas in Bali, Indonesia

This study was performed to assess the seroprevalence against Japanese encephalitis virus (JEV) in chickens collected from an urban area of Denpasar and a rural area of Karangasem in Bali. A total of 142 domestic chickens were sampled and then tested using enzyme linked immunosorbent assay (ELISA) to detect the antibodies. The seroprevalence was calculated in each of the clustered areas and the seropositivity was associated with age and sex of the sampled chickens. The results showed that chickens collected in Denpasar had 97.10% (n=70, 95% CI: 90.88-99.52) seroprevalence against JEV, whereas the chickens collected from Karangasem Regency had a seroprevalence of 93.05% (n=72, 95% CI: 85.28-97.41). In association with area collection, age and sex, chickens collected from Denpasar were 2.5 times (OR: 2.5, 95% CI: 0.48-13.53, P>0.05) more likely to be seropositive containing the antibodies against JEV compared to the chickens from Karangasem Regency. Meanwhile, chickens of age equal to or more than six months were 6.2 times (OR: 6.2, 95% CI: 1.15-33.07, P<0.05) more likely to be seropositive compared to the chickens of age less than six months. The male chickens were 2.4 times (OR: 2.4, 95% CI: 0.45-12.76, P>0.05) more likely to be seropositive compared to females. No significant difference was observed for the seroprevalence in the chickens collected in both areas even though it was found to be significantly associated with the chickens’ age.
THE EFFECTIVENESS OF USING COMIC STRIPS TO TEACH STUDENTS’ READING COMPREHENSION ON NARRATIVE TEXT AT SMK NEGERI 2 SRAGEN

This research is aimed finding the effectiveness of using comic strips as alternativelmedia to teach reading comprehension of narrativettext for tenth grade students of SMK Negeri 2 Sragen academic year 2018/2019. The research-design of thisgstudy was called Quasi-experimental. This study waswusing accidental-sampling whichwused the sampleqprovided by the school. The sample of thiststudy was Class
Using automatic planning to find the most probable alignment: A history-based approach

In many organizational contexts, the existence of a normative process model makes it possible to verify if the actual execution of activities of a business process conforms to that model. Non-conforming behavior can be detected by aligning the actions recorded in the event log with a related normative process model. The alignment approach uses a cost-function to build an execution path that shows which actions do not conform to the model, and which are the expected activities for that trace. In this paper, we are interested on finding the optimal probable alignment using a history-base cost-function, i.e. a function based on the process execution history. For that, we use as a base implementation the planning-based approach, previously proposed in the literature, which demonstrates to find large processes faster when compared to A* for standard cost-functions. We incorporate in this tool the automatic generation of an history-base cost-function to find an optimal probable alignment. In addition, we evaluated our approach using data from both synthetic event logs and a real-life event log.
EVALUATION OF FACTORS AFFECTING INTENTION TO USE QRIS PAYMENT TRANSACTION

The development of mobile payment in Indonesia has been growing rapidly. In 2019 Go-pay, OVO, and DANA dominate mobile payment in Indonesia until Q2 2019. At (cid:12)rst, all three of them have a payment method using QR code in their own way, but now Bank Indonesia has issued regulations on the use of QR payments that use a standard applied throughout Indonesia, namely QRIS. And in 2025, Bank Indonesia has projections that will focus on digital (cid:12)nance, including banking digitization and integration of the national digital economy (cid:12)nance. The research purpose is to identify the factors that in(cid:13)uence people to use QRIS as their mobile payment. The research uses the TAM method and then added several independent variables. The study is conducted by distributing questionnaires to people who use QRIS in Jabodetabek. Then the data is analyzed utilizing the Structural Equation Models (SEM) method using analytical tools, SMART PLS. The result indicates that Attitude toward QRIS payment (ATT) in(cid:13)u-ences the Intention to Use QRIS payment (ITU), and ATT is in(cid:13)uenced by Perceived Ease of Use (PEU) and Perceived Usefulness (PU). And for the added several independent variables, the results are technology anxiety and experience in(cid:13)uence PEU, while social in(cid:13)uence, experience, and compatibility in(cid:13)uence PU.
Medial and lateral dual plating of native distal femur fractures: a systematic literature review

Abstract Introduction: Lateral locked plating (LLP) development has improved outcomes for distal femur fractures. However, there is still a modest rate of nonunion in fractures treated with LLP alone, with higher nonunion risk in high-energy fractures, intra-articular involvement, poor bone quality, severe comminution, or bone loss. Several recent studies have demonstrated both the safety and the biomechanical advantage of dual medial and lateral plating (DP). The purpose of this study was to evaluate the clinical outcomes of DP for native distal femoral fractures by performing a systematic review of the literature. Methods: Studies reporting clinical outcomes for DP of native distal femur fractures were identified and systematically reviewed. Publications without full-text manuscripts, those solely involving periprosthetic fractures, or fractures other than distal femur fractures were excluded. Fracture type, mean follow-up, open versus closed fracture, number of bone grafting procedures, nonunion, reoperation rates, and complication data were collected. Methodologic study quality was assessed using the Coleman methodology score. Results: The initial electronic review and reverse inclusion protocol identified 1484 publications. After removal of duplicates and abstract review to exclude studies that did not discuss clinical treatment of femur fractures with dual plating, 101 potential manuscripts were identified and manually reviewed. After final review, 12 studies were included in this study. There were 199 fractures with average follow-up time of 13.72 months. Unplanned reoperations and nonunion occurred in 19 (8.5%) and 9 (4.5%) cases, respectively. The most frequently reported complications were superficial infection (n = 6, 3%) and deep infection (n = 5, 2.5%) postoperatively. Other complications included delayed union (n = 6, 3%) not requiring additional surgical treatment and knee stiffness in four patients (2%) necessitating manipulation under anesthesia or lysis of adhesions. The average Coleman score was 50.5 (range 13.5–72), suggesting that included studies were of moderate-to-poor quality. Conclusions: Clinical research interest in DP of distal femoral fractures has markedly increased in the past few decades. The current data suggest that DP of native distal femoral fractures is associated with favorable nonunion and reoperation rates compared with previously published rates associated with LLP alone. In the current review, DP of distal femoral fractures was associated with acceptable rates of complications and generally good functional outcomes. More high-quality, directly comparable research is necessary to validate the conclusions of this review.
The formation of galaxy bulges: Spectrophotometric constraints

We have measured Mg 2 , Fe 5270 and Fe 5335 spectrophotometric indices (LICK system) in the bulge of 89 galaxies, mostly spirals from the H(cid:19)eraudeau (1996) sample. The indices are reduced to a null velocity dispersion and normalized to an aperture of 0.2 h − 1 kpc. The mean errors are 0 : 009 mag on Mg 2 , and 0.3 (cid:23)A on the iron indices. These measurements almost double the amount of similar data already available on spiral galaxies. Our data con(cid:12)rm the existence of the relation between Mg 2 and (cid:27) 0 , the central stellar velocity dispersion; we (cid:12)nd an even tighter relation between Mg 2 and V mrot , the maximum rotational velocity of the galaxy, deduced from H i observations. For the most massive bulges, these correlations may be interpreted as a mass-metallicity relation. However, the presence of young stellar populations, traced by the detection of [OIII] (cid:21) 5007 (cid:23)A emission, provides clear evidence that age e(cid:11)ects do play a role. Since the contribution of the young population is anti-correlated to the mass of the galaxy, it continues the Mg 2 vs. (cid:27) 0 relation toward the low- (cid:27) 0 region and globally increases its slope. We also present evidence for a new positive correlation between Fe indices and (cid:27) 0 , and for a signi(cid:12)cant correlation between the line-strength indices and the total or disk luminosity. We propose to model the whole sequence of bulges within the following framework: bulges are composed of a primary population formed prior to the disk, during the initial collapse, and of a secondary population formed during its evolution. The whole family of bulges can be classi(cid:12)ed into three classes: (A) the bulges dominated by young populations are generally small, have ionized gas, low velocity dispersion and low line strengths; (B) the bulges dominated by the primary population lie along the mass-metallicity sequence de(cid:12)ned for elliptical galaxies; and (C) the bulges where the secondary population is signi(cid:12)cant are less Mg-over-abundant than (B)-type bulges and deviate from the Mg 2 vs. (cid:27) 0 relation of elliptical galaxies.
Environmental impact prediction using remote sensing images

Environmental impact prediction is an important step in many environmental studies. A wide variety of methods have been developed in this concern. During this study, remote sensing images were used for environmental impact prediction in Robatkarim area, Iran, during the years of 2005∼2007. It was assumed that environmental impact could be predicted using time series satellite imageries. Natural vegetation cover was chosen as a main environmental element and a case study. Environmental impacts of the regional development on natural vegetation of the area were investigated considering the changes occurred on the extent of natural vegetation cover and the amount of biomass. Vegetation data, land use and land cover classes (as activity factors) within several years were prepared using satellite images. The amount of biomass was measured by Soil-adjusted Vegetation Index (SAVI) and Normalized Difference Vegetation Index (NDVI) based on satellite images. The resulted biomass estimates were tested by the paired samples t-test method. No significant difference was observed between the average biomass of estimated and control samples at the 5% significance level. Finally, regression models were used for the environmental impacts prediction. All obtained regression models for prediction of impacts on natural vegetation cover show values over 0.9 for both correlation coefficient and R-squared. According to the resulted methodology, the prediction models of projects and plans impacts can also be developed for other environmental elements which may be derived using time series remote sensing images.
Aeroelastic Systems with Softening Nonlinearity

Aeroelastic systems with softening nonlinearity are not fully understood. The literature is not definitive, contains partial explanations, and even conflicting results. This problem is addressed for the case of a simple pitch-flap wing, with softening cubic nonlinearity in the pitch stiffness. Complex dynamical behavior is revealed. The study is carried out in three parts, the first of which is the identification and stability analysis of limit cycles in the frequency domain using describing functions combined with the Sherman–Morrison formula. Numerical integration of the nondimensionalized governing equations in the time domain is then carried out and, in addition to confirming the frequency domain results, new behavior is revealed, including asymmetric limit cycles and chaos. Finally, bifurcation analysis is undertaken using numerical continuation methods to reveal Hopf, symmetry breaking (pitchfork), fold and period doubling (flip) bifurcations. The effects of initial conditions and the proximity of l.
On the decay of compressible isotropic turbulence

This paper reports on the extension of second‐order models for unforced isotropic turbulence to the compressible regime. The equations contain two principal compressibility terms: the dilatation dissipation and the pressure–dilatation correlation. The dilatation dissipation has been modeled in accordance with the shocklet dissipation theory of Zeman [Phys. Fluids A 2, 178 (1990)]; the pressure–dilatation term has been identified with the rate of change of compressible potential energy represented by the pressure fluctuation variance ∼(p2). The rate of change of ∼(p2) is assumed to be governed by a nonlinear relaxation mechanism that drives ∼(p2) to an equipartition value. By comparison with direct numerical simulations of 2‐D and 3‐D turbulence, it is shown that the extended turbulence energy equations are capable of simulating the compressibility effects associated with rms Mach number and the (initial) pressure fluctuations.
Swimming at low Reynolds number: a beginners guide to undulatory locomotion

Undulatory locomotion is a means of self-propulsion that relies on the generation and propagation of waves along a body. As a mode of locomotion it is primitive and relatively simple, yet can be remarkably robust. No wonder then, that it is so prevalent across a range of biological scales from motile bacteria to gigantic prehistoric snakes. Key to understanding undulatory locomotion is the body's interplay with the physical environment, which the swimmer or crawler will exploit to generate propulsion, and in some cases, even to generate the underlying undulations. This review focuses by and large on undulators in the low Reynolds number regime, where the physics of the environment can be much more tractable. We review some key concepts and theoretical advances, as well as simulation tools and results applied to selected examples of biological swimmers. In particular, we extend the discussion to some simple cases of locomotion in non-Newtonian media as well as to small animals, in which the nervous system, motor control, body properties and the environment must all be considered to understand how undulations are generated and modulated. To conclude, we review recent progress in microrobotic undulators that may one day become commonplace in applications ranging from toxic waste disposal to minimally invasive surgery.