Miracle-dz/UniFAR-FTUs huggingface dataset:
Identification Of Oxygen Optima For Mouse Trophoblast Stem Cells And Human Embryos And The Stress Responses Upon Departing Optima

IDENTIFICATION OF OXYGEN OPTIMA FOR MOUSE TROPHOBLAST STEM CELLS AND HUMAN EMBRYOS AND THE STRESS RESPONSES UPON DEPARTING OPTIMA by YU YANG May 2017 Advisor: Daniel A. Rappolee, Ph.D Major: Physiology (Reproductive Science Concentration) Degree: Doctor of Philosophy Low level of oxygen (O2) occurs physiologically during in vivo embryo development. As developing embryos moving from fallopian tube to uterus, oxygen level gradually decreases to ≤ 5% at the time of blastocyst implantation. Blastocysts are made of two major cell populations, trophoblast cells and inner cell mass, from which trophoblast stem cells (TSCs) and embryonic stem cells (ESCs) are derived respectively. TSCs serve as placental stem cells that later on proliferate and differentiate into placenta. Previous study has shown that 2% O2 is the optimal O2 level for mTSC in vitro growth and potency maintenance, which agrees with their low O2 niche in vivo. Pathological hypoxia can happen to embryos in pregnancy complicated by certain medical conditions such as sleep apnea, anemia, hypertension or suboptimal living conditions such as high altitude or with carbon monoxide pollution. Here we study the effect of hypoxia at 0.5% O2 on mTSC proliferation and differentiation. We found that 0.5% O2 reduces the growth of mTSC without high levels of apoptosis and forces differentiation despite the potency maintaining conditions. Hypoxic stress induced differentiation has a preference toward trophoblast giant cells
Quality of Life of Chronic Heart Failure Patients

Background: Chronic Heart Failure is a complex clinical conditions affecting patients’ Quality of Life (QoL) globally. Objective: The aim of the study was to identify the factors influencing the quality of life of the chronic heart failure patients. Methods: A descriptive exploratory study was carried out by face-to-face interview with structured standard questionnaire. One hundred and forty two hospitalized chronic heart failure patients were conveniently recruited from National Institute of Cardiovascular Disease and Hospital, Sher-e-Bangla Nagar, Dhaka, Bangladesh. Data were collected from January to February, 2019. Quality of life related factors were identified using Patients’ General Characteristics Questionnaire. QOL of chronic heart failure patients was measured by the Minnesota Living with Heart Failure Questionnaire (MLHFQ) and the World Health Organization’s Quality of Life Instrument-Short Version (WHOQOL-BREF). Descriptive statistic was used to describe the samples’ characteristics. Association between Socio-demographic characteristics and QOL of chronic heart failure patients was measured using t-test and one way of ANOVA. Relationship between continuous variables was measured by Pearson correlation test. Results: Findings reveal that mean of the total chronic heart failure related quality of life was 94.16 (SD = 3.20) out of maximum of 105. This high score indicates worsen chronic heart failure patients’ quality of life. The mean score of general quality of life of chronic heart failure patients was calculated as 41.05 (SD = 5.109) out of maximum of 130 which indicates low level of general quality of life of chronic heart failure patients. There is a significant positive correlation found between disease related quality of life and general quality of life of chronic heart failure patients. Dimensions of physical (r = 0.248, p = 0.000), mental (r = −0.180, p −0.141, p < 0.001) of MLHFQ were significantly correlated with psychological dimension of WHOQOL-BREF except total two dimensions of its. Gender, marital status, education, income, smoking, residence and BMI were identified as factors having an effect on QOL of Chronic Heart Failure patients. Conclusion: Further intervention study is necessary to improve the quality of life of chronic heart failure patients.
Involvement of GSK-3b in TWEAK-mediated NF-jB activation

Glycogen synthase kinase-3b (GSK-3b) is a key component of several signaling pathways. We found that a short variant of 'TNF-like weak inducer of apoptosis' (shortTWEAK) formed a complex with GSK-3b in a yeast two-hybrid system. We demonstrate that shortTWEAK and GSK-3b colocalize in the nucleus of human neuroblastoma cells. We also show that TWEAK is internalized in different cell lines and that it translocates to the nucleus. This event causes the degradation of IBa, the nuclear translocation of both GSK-3b and p65, and the induction of NF-B-driven gene expression. We demonstrate that the induction of IL-8 expression by TWEAK can be counteracted by LiCl. Taken together, these data suggest that GSK-3b plays an important role in the signal transduction pathway between TWEAK and NF-B. 2004 Federation of European Biochemical Societies. Published by Elsevier B.V. All rights reserved.
The Effect of Internationalization on Firm Performance: A Moderating Role of Heterogeneity in TMTs’ Nationality

The effect of internationalization on firm performance has been investigated in the hospitality literature in a relatively extensive manner. However, the literature has still provided mixed findings. Furthermore, the moderating role of top management teams (TMTs) on the relationship between internationalization and firm performance has not been explored yet in the hospitality literature. Considering the increasing importance of internationalization in the hospitality industry and a significant role of TMTs in implementing this internationalization, this study performs a comprehensive examination on the effect of internationalization on firm performance using three different internationalization measures (i.e., degree, diversification, and speed) and three different performance measures (i.e., Tobin’s q, return on assets, and international returns). This study also tests the moderating role of heterogeneity in TMTs’ nationality based on the upper echelons theory, employing hierarchical linear modeling (HLM) to test the proposed hypotheses.
Comparative Analysis of Electrophoretic Profile of Major Proteins of Milk from Alpine and Carpathian Goats

The milk’s proteins provide nutritional and biologically active values, essential in human and animal nutrition. In the case of goat milk, the proteins’ concentration and quality represent important indices for the evaluation of the nutritional and biologically active values. The aim of this study was to comparatively analyze the proteins profile in goat milk from two different breeds: French Alpine and Romanian Carpathian. The milk samples were collected during March and April 2016, in hygienic and sanitation conditions. The proteins profile of goat milk was establish using SDS-PAGE electrophoresis, after the evaluation of the total proteins’ concentration with the Bradford method. The quantitative and percentage data obtained in electrophoresis revealed few differences between identified proteins. In the case of breeds studied has been noted significance differences in terms of the three major proteins in milk β-CN, k-CN and β-lactoglobulin. The other protein fractions have almost identical values. This study brings new contributions in the evaluation and analysis of goat milk protein profile as a nutritive and biologically active component, confirming its character as a functional aliment.
Bamboo hybrid laminate board (Gigantochloa apus) strip with falcata veneer (Paraserianthes falcataria) in selected fiber directions

This study investigated the physical and mechanical properties of bamboo hybrid laminate boards (BHLB) in various fiber directions as a potential wood-replacement structural material. This study used dry bamboo (Gigantochloa apus) processed into thin strips with a thickness of 4 mm and falcata veneer (Paraserianthes falcataria). The BHLB were arranged based on different fiber directions (i.e., perpendicular and parallel) in cold pressing (30 min; 22.2 kgf/cm2) and hot pressing (6 min; 15 kg/cm2). The adhesive used was urea-formaldehyde (UF) resin (glue spread rate of 250 g/m2 and inter veneer 170 g/m2). Physical and mechanical properties were observed to validate the feasibility of preparing BHLB from bamboo strips and falcata veneers. The results showed that the arrangement of the fiber direction affects dimensional stability, MOE (modulus of elasticity), MOR (modulus of rupture), shear strength, and screw withdrawal strength. Falcata veneer as the board core material resulted in lower density, low dimensional stability, and higher water absorption. However, the mechanical properties were not much different and fulfilled the standard for structural use. This study concludes that bamboo can be used for making composite BHLB as an alternative to wood-based composites for structural use.
AGRONOMIC AND DIETARY VALUE OF PAK CHOY (BRASSICA RAPA SSP. CHINENSIS) IN DIFFERENT GROWING PERIODS

Pak choy, in Croatia a less known oriental leafy vegetable species, can be found on the Croatian market in the winter period as an import from other Mediterranean countries. The purpose of the investigation was to obtain information about its agronomic traits and dietary value in different growing periods (two spring and a summer-autumn in the open, and an overwinter period in an unheated high tunnel) from 1998 to 2000. Open field trials were laid out according to the split-plot scheme in five replications, with plant density as the main factor (16.7 and 22.2 plants/m2) and harvest dynamics as the sub-factor [(30, 37 and 44 days after planting (DAP)]. The mono factorial overwinter trial was set up so as to involve supplementary direct covering with polypropylene material (PP) and no covering, at a plant density of 16.7 plants/m2. Undesirable bolting was recorded in spring growing periods (0%, 0 to 9% and 5 to 40% at harvest 30, 37 and 44 DAP, respectively) and in the winter period (with PP covering 2 to 10%, without covering 6 to 20%). Contents of leaf petioles and blades in the rosette mass were about equal in the harvest 30 DAP in both spring periods (ca 45%), and it increased as the vegetation progressed to the advantage of petioles (to 64% at 44 DAP in the summer-autumn period, to 60 % in the overwinter crop). The highest contents of total dietary fibres (0.56 to 0.79 g/100 g fresh matter) and biogenic elements (N, P, K, Ca, Mg, Fe, Mn, Zn and Cu), as well as significantly lower contents of nitrates (1104 to 1187 mg/kg fresh matter) were recorded in the spring growing periods. Closer spacing and supplementary direct crop PP covering had a positive effect on yields (P≤ 0.01) and mainly no significant effect on the other traits studied.
The Role Of Hypoxia and Vascular Growth Factors in Experimental Atherosclerosis

• A submitted manuscript is the version of the article upon submission and before peer-review. There can be important differences between the submitted version and the official published version of record. People interested in the research are advised to contact the author for the final version of the publication, or visit the DOI to the publisher's website. • The final author version and the galley proof are versions of the publication after peer review. • The final published version features the final layout of the paper including the volume, issue and page numbers.
Influences of employees’ perceptions of corporate social responsibility on job satisfaction – A study in Hochiminh City

corporate social responsibility, employee perception, job satisfaction The present study aims to explore the influences of employees’ perceptions of corporate social responsibility (CSR) on their satisfaction in different sectors. The results of the literature review show that there are three components in employees’ perceptions of CSR, including Philanthropic CSR, Ethical CSR, and Environmental CSR; and it is impacted by Perceived CSR capability, Ethical program, and Perceived fit between corporate culture and CSR activities. The research findings have confirmed the proposed hypotheses; and it is obvious that Employees’ perceptions of CSR have a significant impact on Employees’ satisfaction. From the research findings, there are some crucial points to note. Firstly, firms should design their own ethical programs. Secondly, firms should communicate their CSR practices to improve employees’ perceived CSR capabilities. These points are quite important to increase employee satisfaction.
Music as the Medicine of Trauma among Refugees in Arizona

This paper presents outcomes of a phenomenological study conducted to explore the lived experience of refugee musicians. Purposive and snowball sampling methods were used to identify six musicians who performed in the cities of Phoenix and Tucson and had been involved in music prior to entering the United States. The primary data gathering method was structured and unstructured interviews, but observations were made for the musicians who performed in public events during the study period. Audio and video recordings were made and photographs taken during these performances. Study outcomes show that the musicians have persisted in music performance as their primary method of healing trauma and negative emotions. Traumatic experience resulted in their fleeing from their homes and seeking refuge in other countries. After being resettled in the United States, they continue to suffer from the experience of loss, need to adapt and change, and struggle with trauma and negative emotions. Music is their method of healing trauma and facilitating integration. Music produces healing through 1) like a painkiller, enabling them to forget problems that result in distress, 2) being their means to communicate a message of hope, and 3) enabling integration, thus reducing isolation and loneliness.
Effect of post-harvest treatments on shelf life and quality of Guava (Psidiun guavajava) fruits

The study was carried out at Post Harvest Laboratory, College of Agriculture, JNKVV, Jabalpur during the year 2018, on various ripening related changes in guava fruits to determine appropriate maturity stage and postharvest treatment for better quality and desirable shelf life under room storage. Effect of post harvest treatments with Calcium chloride (1 and 2%), Calcium nitrate (0.5 and 1%) and Azadirachta decoction (10 and 20%) on the storage behaviour of guava fruits harvested at colour turning stages during storage at room temperature were studied. Fruits were kept in tray and dipped each for 2 or 4 minutes, storage at room temperature and evaluated after 3, 6, 9 and 12 days for various physico-chemical attributes like. The maximum physiological weight loss 23.34% in untreated fruits and minimum 16.59% in calcium nitrate 1% treated, the maximum TSS was recorded 13.06 brix in calcium nitrate 1% treated and minimum 11.23 brix untreated fruits, the maximum total sugar was recorded 7.09% in calcium nitrate 1% treated and minimum 6.23% in untreated fruits, the maximum reducing sugar was recorded 3.58% in calcium nitrate 1% treated and minimum 3.19% in untreated fruits, the maximum 3.51% in calcium treated 1% and minimum 3.04% in untreated fruits, the maximum acidity recorded was 0.64% in calcium nitrate 1% and minimum 0.42% in untreated fruits and the maximum ascorbic acid was recorded 165.33mg in calcium treated 1% and minimum 133.33mg in untreated fruits at end of the storage period. It was observed that PLW increased, acidity and ascorbic acid decreased during storage irrespective of maturity stages and Calcium treatments studied. However, TSS total sugar, reducing sugar and non reducing sugar increased upto 6 days with all the treatments except control but subsequently decreased thereafter during storage. However, mature green stage fruits exhibited longer shelf life and better fruit quality with all the Calcium treatments compared to calcium treatments stage during storage. Similarly, calcium proved beneficial in delaying the ripening related changes in guava fruits, while application of Ca(NO3)2 (1%) recorded a potential shelf life of 12 days under storage.
Corporate governance and firm performance: Evidence from Vietnamese listed companies

The research aims to provide empirical evidence on the relationship between corporate governance and firm performance in Vietnam – a developing economy in Asia. It focuses on the corporate governance of Vietnamese listed companies with a data-set of the five-year period from 2011 to 2015. Vietnamese listed companies are governed and controlled by two boards, Board of Directors and Supervisory Board. The research investigates the impacts of directors’ and supervisors’ characteristics and ownership structure on firm performance. The outcomes reveal that most governance mechanisms employed by Vietnamese listed companies were not effective and had no effect on the companies’ performance, except for managerial ownership and Supervisory Board size. Specifically, management ownership and firm performance were negatively correlated. Additional analyses show a positive relationship between the number of supervisors and firm performance, which was measured by market-based measurement.
Comparison of Postoperative Pain in Two Groups of Children with Bone Fractures Receiving Pethidine and Paracetamol in Kerman Bahonar Hospital: A Clinical Trial Study

Background Paracetamol and Pethidine are two prevailing analgesics prescribed for postoperative orthopedic patients, each having different side effects and impacts on fracture healing. The present study was conducted to compare the impacts of Paracetamol and Pethidine on postoperative pain relief of children with bone fractures. Materials and Methods: Fifty children with orthopedic bone fracture surgery candidates were selected in a double-blinded clinical trial study. A random number table was utilized to classify children into two groups of Paracetamol or pethidine treatment. First, the pain intensity of each group was checked using the Visual Analog Scale (VAS). Six hours after the surgery, the first group received Pethidine (1mg/kg of body weight), and the second group received Paracetamol (1gr). Moreover, the VAS scales were checked for both groups 6, 12, and 24 hours later. Afterward, the pain intensity of both groups was assessed according to the VAS scale. Results: Independent t-test results revealed a significant difference between the pain intensity of paracetamol (44.24 ± 6.44), and Pethidine (52.68 ± 10.47) groups 6 hours after the surgery (p=0.03). Moreover, there was also a significant statistical difference between the pain intensity of two groups 12 and 24 hours after the surgery. Conclusion Given the effectiveness of Paracetamol and Pethidine on postoperative pain, both medications can be used for children with bone fractures.
Effect of Nimbecidine and Neemazal on the developmental programming of cotton pest, Earias vittella

The toxic effect of Nimbecidine and Neemazal on the reproductive ability of cotton pest, Earias vittella was evaluated under laboratory conditions. Sufficient number of male and female insects was treated with four different doses of Neemazal T/S (0.70, 1.10, 1.50 and 1.90 g/insect) and Nimbecidine (0.90, 1.05, 1.20 and 1.35 g/insect). Six males and six females were used for each treated dose and were paired to mate independently. Each such pair served as one replicate. Results show significant reduction in fecundity, hatchability and adult emergence as compared to that of control. A significant decrease (p<0.001 for each case) in hatchability up to 44% in Neemazal T/S and 32% in Nimbecidine treated Earias vittella were observed. The result also shows that both the pesticides may have a significant effect on the reproduction of the cotton pest, Earias vittella. Therefore, less expensive natural biopesticide could be an alternative for chemical pesticides.
The Influence of Organizational Commitment and Leadership Style Factors through Knowledge Sharing on The Performance of Employees of The State Civil Apparatus in The Investment and One in East Luwu Regency

Improving the quality of government services in the era of globalization and digitalization is a demand for the State Civil Apparatus (SCA) to improve its performance. Employee performance is influenced by several factors such as organizational commitment, leadership st phenomenon that exists in the field today is that the efforts made in building a sense of organization commitment, leadership style and knowledge sharing of each SCA have not been maximized. This also happened at the Investment and One-Door Integrated Services Office (IODISO) of East Luwu Regency. For this reason, this research is expected to be able to provide solutions to the relevant agencies in improving employee performance. The three factors that have been ment with question items in the form of a Likert scale that is submitted to each respondent. So the data obtained in the form of quantitative data. This data is then analyzed using path analysis. The analysis showed organizational commitment and leadership style had a direct positive influence on knowledge sharing significantly. Then organizational commitment, leadership style, and knowledge sharing also have a positive direct effect on employee performance. Whe indirect positive influence through knowledge sharing on employee performance. This organizational commitment, leadership style and knowledge sharing contributed an influence of 92.1% employee performance.
Digital rock physics approach to simulate hydraulic effects of anhydrite cement in Bentheim sandstone

Abstract. Cementation of potential reservoir rocks is a geological risk, which may strongly reduce the productivity and injectivity of a reservoir, and hence prevent utilisation of the geologic subsurface, as it was the case for the geothermal well of Allermohe, Germany. Several field, laboratory and numerical studies examined the observed anhydrite cementation to understand the underlying processes and permeability evolution of the sandstone. In the present study, a digital rock physics approach is used to calculate the permeability variation of a highly resolved three-dimensional model of a Bentheim sandstone. Porosity-permeability relations are determined for reaction- and transport-controlled precipitation regimes, whereby the experimentally observed strong decrease in permeability can be approximated by the transport-limited precipitation assuming mineral growth in regions of high flow velocities. It is characterised by a predominant clogging of pore throats, resulting in a drastic reduction in connectivity of the pore network and can be quantified by a power law with an exponent above ten. Since the location of precipitation within the pore space is crucial for the hydraulic rock properties at the macro scale, the determined porosity-permeability relations should be accounted for in large-scale numerical simulation models to improve their predictive capabilities.
Factors affecting Non-Performing Loans (NPLs) of banks: The case of Vietnam

Non-Performing Loans, longitudinal data, commercial banks, firmly fix-effects model This study aims to identify factors affecting NonPerforming Loans (NPLs) of commercial banks in Vietnam. To address the research problem, data of commercial banks in Vietnam from 2008 to 2017 were collected. This study applied a fixed-effects model in comparison with a random-effects model on a panel data of 200 observations. Results from the firmly fixed-effects model indicated that NPLs were positively affected by its lag of the previous year, capital structure, and interest rate. Additionally, returns on asset, inflation rate, and credit growth were found to have negative impacts on NPLs. However, impacts of firm size and gross domestic product were not found across the models. Based on the results, this research suggested several policy recommendations for the management of NPLs in the commercial banks.