Miracle-dz/UniFAR-FTUs huggingface dataset:
Prevalence and Outcomes in COVID-19 patients with AKI: A meta-analysis

: Objectives: The coronavirus strain first reported in December 2019 (COVID-19) has spread rapidly worldwide, posing a seriously risk to human health. This meta-analysis aims to shed much-needed light on the relationship between COVID-19 and AKI, and provide a stronger evidence base to support both further research and clinical application. Methods: Two authors independently performed a literature search using PubMed, Web of Science, Embase, and Cochrane Library. Then the incidence of AKI, incidence of RRT required, the mortality rate with AKI and the risk of death with AKI during a COVID-19 infection were statistically analyzed using Open Meta-Analyst software, from which conclusions are derived. Results: The incidence of AKI in hospitalized patients with the COVID-19 infection remains low, only about 3.8%; the in-hospital mortality rate with AKI in COVID-19 infected patients reaches up to 86.8%; the odds of death with AKI in COVID-19 infected patients is about 24.2 times higher than those without AKI. Conclusions: The occurrence of AKI during a COVID-19 infection should be considered a strong red flag with regards to the patient’s risk of death. Additional studies are still required to support the conclusions derived herein and to explore the AKI mechanism during a COVID-19 infection. and control of critical cases with AKI; the renal function of asymptomatic and mild cases should be frequently monitored, carried out blood purification treatment if necessary; (2) Conduct in-depth research on mechanisms of renal injury during COVID-19 attack (various signal pathways/virus proteins) for designing of blocking drugs; (3) Explore the combined application of antiviral and anti-inflammatory drugs in the design of clinical trials for COVID-19, further study is needed on the standard application, the evaluation for the curative effect, and the integration of them together. Finally to ameliorate the effectiveness of treatment, as well as to achieve the goal of reducing mortality patients infected with COVID-19.
Examining the stress, depressive thoughts, and working memory capacities of the university students

The objective of the study is to measure the capacity of the working memory, and also to investigate its relationship to life stress and depressive thoughts. The study sample consisted of 50 college students studied on Science and Art major. A cognitive task was designed to measure the working memory capacity based on the determinants found in previous research. The results indicated that there were statistically significant differences in the level of life stress events (high/low) on the task of measuring the working memory capacity. The results also showed that there were no statistically significant differences neither between genders nor between majors on the task of measuring the working memory capacity. Furthermore, the results reported that there was no statistically significant effect of the interaction of the level of life stress (high/low) and gender (male/female) on the task of measuring working memory capacity. Finally, the results reported that there were significant differences in the level of depressive thoughts (high/low) on the task of measuring working memory. The current research concludes that neither the interaction of stressful life events, gender, and academic major, nor the interaction of depressive thoughts, gender, and academic major have an effect on working memory capacity.
A review of the major drivers of the terrestrial carbon uptake: model-based assessments, consensus, and uncertainties

Terrestrial and oceanic carbon sinks together sequester > 50% of the anthropogenic emissions, and the major uncertainty in the global carbon budget is related to the terrestrial carbon cycle. Hence, it is important to understand the major drivers of the land carbon uptake to make informed decisions on climate change mitigation policies. In this paper, we assess the major drivers of the land carbon uptake — CO 2 fertilization, nitrogen deposition, climate change, and land use / land cover changes ( LULCC ) — from existing literature for the historical period and future scenarios, focusing on the results from ﬁ fth Coupled Models Intercomparison Project ( CMIP5 ) . The existing literature shows that the LULCC ﬂ uxes have led to a decline in the terrestrial carbon stocks during the historical period, despite positive contributions from CO 2 fertilization and nitrogen deposition. However, several studies ﬁ nd increases in the land carbon sink in recent decades and suggest that CO 2 fertilization is the primary driver ( up to 85% ) of this increase followed by nitrogen deposition ( ∼ 10% – 20% ) . For the 21st century, terrestrial carbon stocks are projected to increase in the majority of CMIP5 simulations under the representative concentration pathway 2.6 ( RCP2.6 ) , RCP4.5, and RCP8.5 scenarios, mainly due to CO 2 fertilization. These projections indicate that the effects of nitrogen deposition in future scenarios are small ( ∼ 2% – 10% ) , and climate warming would lead to a loss of land carbon. The vast majority of the studies consider the effects of only one or two of the drivers, impairing comprehensive assessments of the relative contributions of the drivers. Further, the broad range in magnitudes and scenario / model dependence of the sensitivity factors pose challenges in unambiguous projections of land carbon uptake. Improved representation of processes such as LULCC, ﬁ res, nutrient limitation and permafrost thawing in the models are necessary to constrain the present-day carbon cycle and for more accurate future projections.
Nuova tecnologia per la prpoduzione dui Ricotta ovina: caratteristiche e valutazione della conservabilità

Two different technological processes, the traditional way and a new mechanical method, were used for the production of sheep Ricotta cheese, with the purpose to obtain a product with an improved yield and an increased shelf-life but with organoleptic characteristics similar to those of the traditional Ricotta. The application of the new technology allowed a yield of long-life Ricotta more than 10% in all experimentations. Chemical and microbiological analyses were carried out on both types of Ricotta, after the production and during conservation. Chemical and organoleptical analyses gave similar results for both types of Ricotta. Microbiological analyses demonstrated that traditional Ricotta always had a higher contamination than long-life Ricotta. The contaminants isolated were represented by microorganisms considered an index of unsatisfactory hygienic conditions during production. On the contrary, due to the new mechanical technology adopted, the long-life Ricotta sampled showed good organoleptic characteristics and hygienic quality even after 30 days of conservation
Force identification with use of spatial filter based on ODS

In last few decades it can be observed that there is a significant growth of the interest in the structural health monitoring (SHM) systems development and applications. Unfortunately many authors focuses only on the damage detection and other activities related with diagnosis of fault. Meanwhile, classical SHM system by definition should have in addition to a diagnostic module also module for load monitoring. This load can be measured, but easier and cheaper is to identify it from the measured response of the object. Often it is the only practical possibility to monitor the excitation. The paper presents a trial to apply a spatial filter based on operational deflection shapes (ODS) to force identification. The idea of spatial filter will be shown together with the method of force reconstruction. The simulation verification and comparison with classical modal filter will be also provided.
Weighing in on Weight Discrimination Against Females of Different Races

With increased obesity rates, more individuals are likely to experience weight-related employment discrimination. In this 2 (weight) by 3 (race) design, overweight female job applicants received lower hiring and salary recommendations than normal weight females. There were no significant race differences in hiring and salary recommendations across Black, Hispanic, and White female job applicants in hiring and salary recommendations. Explicit and implicit measures of weight bias were modestly correlated. Only explicit weight bias predicted hiring recommendations. Results showed that managers’ explicit weight biases may impact their hiring recommendations and suggest that qualified, overweight individuals may be passed over in the hiring process.
Draft 1 1 An Optimization Model for Selecting Wood Supply Contracts 2

Journal: Canadian Journal of Forest Research Manuscript ID cjfr-2019-0281.R2 Manuscript Type: Article Date Submitted by the Author: 11-Dec-2019 Complete List of Authors: Rahimi, Ali; Université Laval, Département de génie mécanique Rönnqvist, Mikael; Université Laval, Département de génie mécanique LeBel, Luc; Université Laval, Département des sciences du bois et de la forêt Audy, Jean-François; Université du Québec à Trois-Rivières, Department of Management Keyword: Contract Selection, Procurement, Mixed-integer Programming, Pulp and Paper, Supplier Portfolio Strategy Is the invited manuscript for consideration in a Special Issue? : Not applicable (regular submission)
Entrepreneurship Instruction with Information and Communication Technology (ICT) and Improvement of Entrepreneurial Practices in Nigeria for Global Competitiveness

This study investigated how ICT can be used to enhance entrepreneurship instruction for the improvement of entrepreneurial practices in Nigeria for global competitiveness. Four research questions were posed and one null hypothesis formulated to guide the study. The population of the study comprises all one thousand six hundred (1,600) entrepreneurship learners in tertiary institutions in Imo state Nigeria. Stratified random sampling technique was used to select four hundred (400) learners from five (5) tertiary institutions in the State. Purposive sampling technique was also used to select Fourty entrepreneurship and Business Education instructors. Data were collected with use of 20-item research questionnaire titled Entrepreneurship Instruction with ICT and Improvement of Entrepreneurial Practices Questionnaire (EIIEPQ), and semi-structured interview for instructors. Data obtained were analyzed using, independent t-test, and descriptive statistics (frequencies and mean score). Results obtained revealed that ICTs that are relevant for entrepreneurship education has not been adequately provided for entrepreneurship studies in universities to foster teaching-learning of international standard. Diverse ways ICT can be used in entrepreneurship education, is seen to be applied at relative low frequency by instructors. The results also showed that instructions on entrepreneurship delivered with the use of ICT significantly influence entrepreneurship attitude development in learners for global competitiveness in entrepreneurial practices. And that students have not adequately been taught ICT application in doing business as part of entrepreneurship curriculum to enhance production of globally competitive entrepreneurs from the educational system. Based on the results and findings from the study, it is recommended that; Facilitators of entrepreneurship education should be provided with adequate in-service training on using ICT for entrepreneurship teaching-learning and for research purposes. This will serve to encourage them to employ these equipment frequently in teaching-learning of entrepreneurship, for better outcomes. Provision should be made for students to learn ICT application in business as part of the content of the entrepreneurship studies. These should be taught by experts to enhance their efficiency on that, since ICT application in business is overwhelming in this global age.
THE EFFECT OF SACCHAROMYCES CEREVISIAE USED ALONE OR WITH VITAMIN-MINERAL PREMIX ON BIOCHEMICAL PARAMETERS OF BLOOD AND MILK IN DAIRY COWS

When evaluating the effects of yeast culture (Saccharomyces cerevisiae 1026 ) supplied with or without a vitamin premix and mineral bioplexes on some intermedi-ates and end-products involved in the synthesis of milk constituents in 30 early-lactation Black and White Lowland cows, no significant differences were found in the glucose level, mineral contents and enzyme activities of the blood serum. The effect of yeast culture on the availability of minerals for milk synthesis depended upon the dynamics of degradation of mineral bioplexes in the rumen and the cows(cid:146) mineral status. The insignificant increase found in blood total protein content and the simultaneous small differences in blood urea nitrogen (BUN) and milk urea nitrogen (MUN) values in cows supplied with the yeast culture were probably associated with a high ammonia incorporation into microbial protein in the rumen, which increased protein supply for milk protein synthesis and decreased the nitrogen loss.
TEMPORAL VARIATION OF GROUNDWATER RESOURCES IN ILESA WEST LOCAL GOVERNMENT, OSUN STATE NIGERIA

The study was carried out to investigate the different groundwater resources and to generate the temporal differences over the different seasons in Ilesa West Local Government, Osun State, Nigeria. The LGA has not been provided with municipal pipe-borne water supply for over 30 years, hence they are exclusively using groundwater in form of boreholes, dugwells and springs. The physico- chemical and heavy metal parameters were determined over a period of one year covering the rainy and dry seasons. A total of 69 drinking water points which comprises of 63 dugwells, 5 boreholes and 1 spring were used for the study and they were selected to represent the built-up part of the entire study area adequately. Parameters analysed were pH, electrical conductivity (EC), temperature, total dissolved solids (TDS), chloride, sulphate, nitrate, sodium, potassium (K), calcium, magnesium, hardness, alkalinity, bicarbonate using standard methods. Analysis of heavy metals (Fe, Cr) was carried out with atomic absorption spectrophotometer (AAS) and microbiological analysis was conducted using most probable number (MPN) of counting coliforms. The data generated were subjected to descriptive statistics and line graph. The analysis of the different groundwater resources revealed a good water quality but the values of pH, TDS, EC, K, were higher than the permissible range. The concentration of Fe and Cr is very high and could constitute some health hazards in some sources. The temporal variation of the water quality parameters did not follow any definite trend but the pH, NO 3 , TDS, HCO 3 , SO 4 , Fe, Cr were highest in the dry months of April and December, while Ca, Mg, K, Na, hardness, and alkalinity were highest in the rainy months of June and August. The percentage of microbial distribution was highest in the months of June in the boreholes and the spring but the distribution in the dugwells was entirely different. The water from the boreholes and dugwells were generally soft and should be checked for plumbo-solvency. It is recommended that a routine monitoring of all the sources should be carried out and a treatment that will reduce the heavy metals concentrations be enforced.
Influences of Structural Assurances on Continuance Intention towards the Blockchain-based Online Healthcare Mutual Aid Platform

Drawing upon perceived justice and trust literature, this study developed a research model to examine two types of platform assurances, specifically policy assurance and technology assurance, on users’ continuance intention towards “Xianghubao”, which is recognized as one of the largest online healthcare mutual aid platform supported by blockchain technology. A free simulation experiment was conducted and structural equation modelling technique was used to test the research model. The empirical results suggested that two assurance mechanisms exhibited significant influences on perceived procedural justice and trust, which further promoted continuance intention to different degrees. This study contributes to the extant literature by identifying blockchain technology as a salient technology assurance in the context of online healthcare platform, and uncovering its influence mechanism on continuance intention from a lens of justice and trust.
Peroxisome Proliferator-activated Receptor (cid:1) Ligands Inhibit Mitogenic Induction of p21 Cip1 by Modulating the Protein Kinase C (cid:2) Pathway in Vascular Smooth Muscle Cells*

The cyclin-dependent kinase inhibitor p21 Cip1 is up-regulated in response to mitogenic stimulation in various cells. PPAR (cid:1) ligands troglitazone (TRO, 10 (cid:3) M ) and rosiglitazone (RSG, 10 (cid:3) M ) attenuated the induction of p21 Cip1 protein by platelet-derived growth factor (PDGF) and insulin without affecting cognate mRNA levels in rat aortic smooth muscle cells (RASMC). The protein kinase C (cid:2) (PKC (cid:2) ) inhibitor rottlerin also blocked the induction of p21 Cip1 protein, whereas the conventional PKC isotype inhibitor Go¨ 6976 had no effect. Kinetic studies using the protein synthesis inhibitor cycloheximide showed that TRO, RSG, and rottlerin shortened the half-life of p21 Cip1 protein. TRO, RSG, and rottlerin inhibited PDGF-induced expression of p21 Cip1 they did not affect insulin-induced expression of p21 Cip1 . Both ligands inhibited PKC (cid:2) enzymatic activity in PDGF-stimulated RASMC not in insulin-stimulated cells. Adenovirus-mediated overexpression of PKC (cid:2) down-regulation of p21 Cip1 expression both by TRO and RSG in PDGF-treated RASMC. These data suggested that the PKC (cid:2) pathway plays a critical role in PDGF-induced expression of p21 Cip1 in RASMC and may be the potential target for PPAR (cid:1) ligand effects. Src kinase-dependent tyrosine phosphorylation of PKC (cid:2) decreased substantially by TRO and RSG. Tyrosine phosphorylation and activation of c-Src in response to PDGF were unaffected by either PPAR (cid:1) ligand. Protein-tyrosine-phosphatase inhibitors sodium orthovanadate and dephostatin prevented PPAR (cid:1) ligand effects on PKC (cid:2) tyrosine phosphorylation and enzymatic activity. Both inhibitors also reversed PPAR (cid:1) ligand effects on p21 Cip1 expression in PDGF-treated RASMC. PPAR (cid:1) ligands enhanced protein-tyrosine-phosphatase activity in RASMC, which may be the mechanism for decreased PKC (cid:2) tyrosine phosphorylation and activity. PPAR (cid:1) ligands regulate p21 Cip1 at a post-translational level by blocking PKC (cid:2) signaling and accelerating p21 Cip1 turnover.
Estimâtes of Circulating Monomeric Calcitonin: Physiological Studies in Normal and Thyroidectomized Man*

To avoid the limitations of présent human cal­ citonin (hCT) assays, we have developed a silica extraction and concentration method for plasma hCT that lowers the détection limit of the assay 40­fold (to 0.5­1.0 pg/ml), and markedly improves specificity of the assay for the CT monomer (hCT­M). Extraction recoveries of radioiodinated and unlabeled synthetic hCT­M added to 20 ml plasma were, respectively, 90 ± 1% and 99 ± 4% (mean ± SE). Gel filtration chromatography of plasma from patients with meduUary thyroid carcinoma demonstrated that the extract was markedly enriched in hCT­M. Basai plasma immunoreactive hCT was measured before (iCT) and after ex­ traction (exCT) in 60 normal individuals; basai exCT levels were higher in young men than in young women [8.0 ± 0.8 (± SE) vs. 4.6 ± 0.5 pg/ml; P < 0.001] and higher in elderly men than in elderly women (9.4 ± 0.8 us. 4.7 ± 0.6 pg/ml; P < 0.05), but not différent with âge. Calcium infusions (2 mg Ca/kg over 5 min) in 36 subjects showed a significantly greater secretory capacity for exCT in men than in women, but showed no décline of exCT response with âge. There was no corrélation between basai iCT and exCT concentrations, but there was a good corrélation between peak Ca­stimulated iCT and peak Ca­stimulated exCT levels (r = 0.94; P < 0.001), suggesting that hCT­M was the main form released by acute stimulation. The mean extractable CT level in 6 totally thyroidectomized individuals was 2.7 ± 0.3 pg/ml and did not increase after Ca challenge. We found no significant différences in basai or Ca­stimulated exCT levels measured in 5 women on 3 différent occasions over the span of 1 menstrual cycle. After a meal, exCT levels did not change in women, but there was a consistent increase in the men (28 ± 7% over baseline at 3 h; P < 0.01). In summary, plasma concen­ trations of exCT and, most likely, hCT­M were very low (<10 pg/ml in most healthy adults) and always increased after calcium infusion. The measurement of plasma exCT is a useful technique that provides new sensitivity and specificity for the study of hCT physiology. (J Clin Endocrinol Metab 57: 897, 1983)
Valuation of fermentation residues from biogas stations

ABSTRACT The recent decade of unprecedented support for renewable energy in Central Europe has led to a boom in the construction of biogas plants (among others). As renewables are coming close to being price competitive, this trend is passing onto a global scale and it is the developing countries in particular that are interested in technology transfer. Regardless of whether the biogas plant processes biowaste or purpose-grown phytomass, nowadays both are interlinked with farming practice, because it generates voluminous quantities of highly-diluted fermentation residues (FRs). These are routinely plowed into local arable land, however, there are uncertainties regarding their agrochemical and economic value. The market price of the FRs has stabilized under one third of what was expected at the beginning of the biogas fever. This has caused unexpected cash-flow problems to some business projects. Analyses revealed multiple reasons for the initial overestimation. It is indicated that the most overrated factor is the quality of organic matter in the FRs. Its low biodegradability limits the metabolism of nitrogen-mineralizing soil biota, which consequently slows the transformation of organic nitrogen into mineral forms that are accepted by plants. To make matters worse, the slow decomposition of hardly biodegradable organic matter forms preconditions that lead to worse water-retention soil characteristics.
Effect of Dexamethasone on Antepartum Cardiotocography

Objective: The purpose of this study was to evaluate the effect of dexamethasone on fetal heart rate parameters using the standard dose regimen. Study Design: A prospective cohort study conducted in the Maternity Department, Suez Canal University hospitals. Sixty- eight pregnant women with gestational age between 28 and 34 weeks were recruited. Patients received 4 doses of dexamethasone 6 mg every 12 hours for threatened preterm delivery due to preterm premature rupture of membranes, placenta previa or history of preterm labor. Computerized cardiotocography was recorded for 60 minutes on day 0 (before dexamethasone administration), day 2 and day 4 after administration. Cardiotocography monitoring was performed between 11 am and 1 pm to avoid diurnal rhythm of fetal heart rate. Outcome measure included changes in fetal heart rate accelerations, variability and fetal movements following dexamethasone injection. Results: Sixty-eight patients were enrolled in the study. Fetal heart rate accelerations (P=0.0001), short-term variation (P=0.01), episodes of high variation (P=0.003) and fetal movements (P=0.0001) were significantly reduced on day 2 after dexamethasone. No significant changes were found on baseline fetal heart rate (P=0.18), long-term variation (P=0.1) and number of decelerations (P=0.1). All parameters returned to baseline values on Day 4 after administration. Conclusion: Dexamethasone induces transient suppression of fetal heart rate parameters on day 2 after administration that mimics fetal compromise. Awareness of this phenomenon is important to avoid iatrogenic delivery of preterm fetuses.