Miracle-dz/UniFAR-FTUs huggingface dataset:
Genome-Wide Identification, Characterization and Expression Analysis of the TaDUF724 Gene Family in Wheat (Triticum aestivum)

Unknown functional domain (DUF) proteins constitute a large number of functionally uncharacterized protein families in eukaryotes. DUF724s play crucial roles in plants. However, the insight understanding of wheat TaDUF724s is currently lacking. To explore the possible function of TaDUF724s in wheat growth and development and stress response, the family members were systematically identified and characterized. In total, 14 TaDUF724s were detected from a wheat reference genome; they are unevenly distributed across the 11 chromosomes, and, according to chromosome location, they were named TaDUF724-1 to TaDUF724-14. Evolution analysis revealed that TaDUF724s were under negative selection, and fragment replication was the main reason for family expansion. All TaDUF724s are unstable proteins; most TaDUF724s are acidic and hydrophilic. They were predicted to be located in the nucleus and chloroplast. The promoter regions of TaDUF724s were enriched with the cis-elements functionally associated with growth and development, as well as being hormone-responsive. Expression profiling showed that TaDUF724-9 was highly expressed in seedings, roots, leaves, stems, spikes and grains, and strongly expressed throughout the whole growth period. The 12 TaDUF724 were post-transcription regulated by 12 wheat MicroRNA (miRNA) through cleavage and translation. RT-qPCR showed that six TaDUF724s were regulated by biological and abiotic stresses. Conclusively, TaDUF724s were systematically analyzed using bioinformatics methods, which laid a theoretical foundation for clarifying the function of TaDUF724s in wheat.
Decadal and Seasonal Dependence of ENSO Prediction Skill

Abstract When forecasting sea surface temperature (SST) in the Equatorial Pacific on a timescale of several seasons, most prediction schemes have a spring barrier; that is, they have skill scores that are substantially lower when predicting northern spring and summer conditions compared to autumn and winter. This feature is investigated by examining predictions during the 1970s and the 1980s, using a dynamic ocean model of intermediate complexity coupled to a statistical atmosphere. Results show that predictions initialized during the 1970s exhibit the typical prominent skill decay in spring, whereas the seasonal dependence in those predictions initialized during the 1980s is rather small. Similar changes in seasonal dependence are also found in predictions based on simple persistence of observed SST anomalies. This decadal change in the spring barrier is related to decadal variations found in the seasonal phase locking of the SST anomalies, which is largely determined by the timing of El Nino events. The.
Assessing the impact of climate change on fluvial flood losses in urban areas: a case study of Pamplona (Spain)

ABSTRACT Climate change is expected to increase the frequency and magnitude of flooding. Furthermore, in recent years, there has been an increase in city extent and population densities. This study considers the metropolitan area of Pamplona (Spain) as a case study. The delta changes in precipitation quantiles in the Arga River catchment, obtained from 12 climate models, have been transformed into peak flow delta changes using the Real-time Interactive Basin Simulator (RIBS) model. Also, three percentiles of flood quantile delta changes are selected. Water depths and flood extents expected in future flood events have been obtained using the two-dimensional Iber hydrodynamic model. The Safer_DAMAGE algorithm has been used to assess flood losses in urban areas at the building scale. The results show that flood losses are expected to be smaller for low return periods and greater for high return periods.
C-reactive protein: a critical update.

In the mid 1990s, immunoassays for C-reactive protein (CRP), with greater sensitivity than those previously in routine use, revealed that increased CRP values, even within the range previously considered normal, strongly predict future coronary events. These findings triggered widespread interest, especially, remarkably, in the US, where the clinical use of CRP measurement had been largely ignored for about 30 years. CRP production is part of the nonspecific acute-phase response to most forms of inflammation, infection, and tissue damage and was therefore considered not to provide clinically useful information. Indeed, CRP values can never be diagnostic on their own and can only be interpreted at the bedside, in full knowledge of all other clinical and pathological results. However, they can then contribute powerfully to management, just as universal recording of the patient’s temperature, an equally nonspecific parameter, is of great clinical utility. The present torrent of studies of CRP in cardiovascular disease and associated conditions is facilitated by the ready commercial availability of automated CRP assays and of CRP itself as a research reagent. However, unlike the earlier rejection in the US of CRP as an empirical test because of its perceived lack of specificity, the current enthusiasm over CRP in cardiovascular disease is widely characterized by failure to recognize appropriately the nonspecific nature of the acute-phase response, and by lack of critical biological judgment. Quality control of the source, purity, and structural and functional integrity of the CRP, and the relevance of experimental design before ascribing pathophysiological functions, are also often ignored. This article provides information about CRP as a protein and an acute-phase reactant, and a knowledge-based framework for interpretation and analysis of clinical observations of CRP in relation to cardiovascular and other diseases. We also review the properties of CRP, its possible role in pathogenesis of disease, and our own observations that identify it as a possible therapeutic target.
UvA-DARE (Digital Academic Repository) Practice what you preach: The moderating role of teacher attitudes on the relationship between prejudice reduction and student engagement

(cid:1) Using multilevel models, we examined the relationship between teachers' prejudice reduction practices and students' engagement. (cid:1) Prejudice reduction practices focused on engaging in dialogue about diversity and confronting intergroup bias. (cid:1) Teachers' explicit multicultural attitudes and implicit attitudes towards ethnic minorities were possible moderators. (cid:1) Prejudice reduction predicted increases in student engagement for teachers with above-average positive explicit attitudes. (cid:1) Our models did not support such an interaction effect for implicit ethnic attitudes.
Social Exclusion: A Bibliometric Analysis and Future Research Directions in Advertising

Abstract Advertisers have begun to recognize the role of inclusive advertising in consumer well-being. One way to increase inclusivity is to minimize experiences of exclusion using marketing tools. Although social exclusion is common in today’s world, current academic literature is mostly silent on how advertising can mitigate the negative effects of exclusion. This article initiates the discussion on inclusive advertising by systematically exploring the underlying phenomena of social exclusion and related concepts (e.g., marginalization, loneliness, and social isolation). Through a bibliometric approach and thematic content analyses that includes more than 490 articles published in the last two decades in marketing, including advertising, communication, and psychology journals, we evaluate the mechanisms and consequences of social exclusion. We discuss several avenues for future research, present propositions, and suggest guidelines on (1) how marketers can design inclusive advertising, (2) how advertising can cater to the needs of excluded consumers, and (3) how advertising may alleviate the negative effects of social exclusion and enhance consumer psychological well-being.
Public participation and the integrated development planning : the case of Limpopo Province

The municipal ward committees and IDP Representative Forums are the arenas within which integrated development planning takes place, the end-results are IDP documents that have to be reviewed annually to incorporate social learning, emerging priorities and new resource opportunities. The key assumption is that decisions on development are more viable, effective and sustainable when the people they affect are integrally part of the decision-making - and the implementation - process. This article examines the variety of channels and processes for public participation in the integrated development planning (IDP) processes in the Limpopo Province. It also focuses on the policy and legislative framework underpinning public participation in the IDP processes. Legislation requires that the IDP process should structurally incorporate the voice of communities affected by planning. It is expected that participation in local development planning should address the real needs of local communities. The notion of public participation is central to the IDP model. Despite the opportunities that have been created for public participation in the IDP processes, the article argues, the poor and the marginalised groups still have far less influence in governing and policy-making processes than other more organised interest groups.
A well‐established Early–Middle Pleistocene marine sequence on south‐east Zakynthos island, western Greece: Magneto‐biostratigraphic constraints and palaeoclimatic implications

The chronostratigraphy of a long, onshore Early–Middle Pleistocene marine sedimentary sequence on the south‐east part of Zakynthos island, Greece, is presented. Correlation of the succession with the isotope record of Ocean Drilling Program Site 963 reveals the combined influence of tectonics and eustacy in this area. The sequence is divided into three formations by two main unconformities that apparently relate to sea‐level lowstands associated with two major northern hemisphere glaciations, those of marine isotope stages (MIS) 22 and 12. The Zakynthos sequence in many ways is comparable with the Italian Valle di Manche section. Magnetostratigraphic and rock magnetic analyses, supported by biostratigraphy, document the position of the Matuyama/Brunhes Chron boundary (0.77 Ma), the top and base of the Jaramillo Subchron (0.99–1.07 Ma), the Cobb Mountain Subchron (1.173–1.185 Ma) and the top of the Olduvai Subchron (1.78 Ma). The underlying strata are constrained exclusively by detailed nannofossil biostratigraphy extending at least to the lowermost Pleistocene at around 2.54 Ma and therefore certainly incorporating the base of the Olduvai Subchron (1.95 Ma) and possibly the Gauss/Matuyama Chron boundary (2.58 Ma). In addition, a remarkable increase in sedimentation rate (from 3.2 and 28 cm ka−1 to 167 cm ka−1) and hence resolution above the Matuyama/Brunhes boundary (Middle Pleistocene) reveals one short‐lived magnetic excursion, possibly 17a (0.66 Ma), within the normal polarity Brunhes Chron. Copyright © 2011 John Wiley & Sons, Ltd.
Structural and lithological controls on the high-grade Hangingwall Reef quartz – gold veins, Stawell, Victoria

The Hangingwall reefs are high-grade auriferous quartz lodes that occur in the upper levels of the Magdala mine at Stawell, and thus represent an important deposit style in western Victoria. Structural relationships indicate that the Hangingwall Reefs formed coincident with the same metallogenic event that produced the adjacent Magdala deposit. However, the host-rocks to the quartz – gold veins that make up the Hangingwall Reefs display markedly different structural and stratigraphic relationships. Hangingwall Reef mineralisation occurred during east – west shortening in a muscovite-altered turbidite sequence that had little prior iron alteration (cf. Magdala deposit). Lithological and structural data show that the distribution of the quartz – gold veins is related to the geometry of the Stawell Fault and its associated fault splays, with the quartz veining being localised where the faults are discordant with the pre-existing structural fabrics. This discordant relationship produced the dilational sites and jogs in which the auriferous quartz veins formed. Results from 3D numerical modelling show that dilation along the Stawell Fault provided the conduit for fluid flow.
Carbapenem-Resistant Enterobacteriaceae Bacteraemia in Intensive Care Unit: A Descriptive Study on Risk Factors and Clinical Outcome

INTRODUCTION: Over the past 10 years, the prevalence of carbapenem-resistant Enterobacteriaceae (CRE) has been increasing dramatically with numerous hospital outbreaks reported. Bacteraemia caused by CRE have limited treatment options and have been associated with high mortality rates. As a result, preventing both CRE transmission and CRE bloodstream infections have become important objectives in managing intensive care unit (ICU) patients. The study aims to determine the incidence and risk factors of CRE bacteraemia in intensive care settings, and its’ clinical outcome. MATERIALS AND METHODS: A retrospective, descriptive study was conducted, where data of the patients admitted to general ICU of Hospital Pulau Pinang from January 2017 till December 2018 were collected and assessed for incidence, presence of predisposing factors and clinical outcome for CRE bloodstream infection. RESULTS: Out of 2,585 total ICU admissions, there were 37 cases of CRE bacteraemia with an incidence rate of 1.43%. An analysis of risk factors revealed that the use of indwelling catheter has the highest association with CRE bacteraemia in which 95% of the patients were exposed. The commonest organisms of CRE bacteraemia were Klebsiella pneumoniae (97.3%) and Escherichia coli (2.7%). The 30-day mortality rate after CRE bacteraemia was 78.4%. CONCLUSION: CRE bacteraemia among ICU patients showed a high mortality rate. Most of the patients were exposed to multiple risk factors. A high index of suspicion and rapid identification of patients at risk for CRE infection are important for effective therapy and initiation of infection control measures to prevent further spread.
Marriage Practices in an Urban Slum: Vulnerability, Challenges to Traditional Arrangements and Resistance by Adolescent Women in Dhaka, Bangladesh

Compared to Southeast Asia, Dhaka city represents an apparent anomaly: a rapidly growing metropolis with relatively little change in early marriage practices, with 51 percent of 15-19 year-old females in 2000 already married. The rapid influx of rural poor families to Dhaka has led to a rapid increase in urban population growth, slum settlements and worsening poverty. Ethnographic fieldwork among married adolescent girls, aged 15-19, was carried out in a Dhaka slum from December 2001 to January 2003, including 50 in-depth interviews, 8 case studies from among 153 married adolescent girls, and observations and discussions with family and community. Informed by critical medical anthropology [1], this paper is about how early marriage practices and marital instability in an urban slum in Dhaka are grounded in the social, political and economic structures of their lives. A climate of poverty, violence and insecurity encourage early marriage practices and incidents of coerced marriages. Lawlessness, fears of sexual harassment and gang wars are a motivating factor for many families. In addition, the incentive to pay smaller dowries for poor families especially if their daughter is younger is also a motivating factor. While urbanization and the advent of the garment industry has increased employment opportunities and options for young girls, this has also led to a shift in traditional marriage arrangements, with greater incidence of love marriages, without parental permission at times. Incidents of young women resisting marriages organised by parents highlight a shift in parental authority as increasingly girls who work assert their agency, preferring to select and choose their own partners. The reasons for early marriage in a slum are shaped increasingly by structural and social inequalities which compel families and young women to make choices and trade-offs in order to survive in the difficult environment. [1] Disease is understood to be social as well as biological, and there is a focus on the links between disease and social class, poverty, power and ill health, i.e. the political economy of health.
Influenza vaccination: key facts for general practitioners in Europe—a synthesis by European experts based on national guidelines and best practices in the United Kingdom and the Netherlands

Currently there is no influenza vaccination guidance for European general practitioners. Furthermore, although the European Council recommends a target seasonal influenza vaccination rate of 75% in the elderly (65 years and above) and in anyone aged >6 months with a chronic medical condition, there remain wide discrepancies throughout Europe. A harmonised guideline regarding not only vaccination strategy but also for the consistent diagnosis of influenza across Europe is essential to support a common approach for the implementation of seasonal influenza vaccination across Europe. This document is based on pre-existing guidelines available in the UK and Netherlands and has been approved by a group of European experts for use throughout Europe. As well as providing a standardised influenza diagnosis, it also reviews the current recommendations for influenza vaccination, the types of vaccine available, the contraindications, vaccine use in special populations (in pregnancy, children, and in those with egg allergy), and concomitant administration with other vaccines. The effectiveness, safety, and timing of the seasonal influenza vaccine are also reviewed. A second section provides practical guidance for general practitioners for the implementation of a seasonal influenza vaccination program, including the selection and notification of those eligible for vaccination, as well as suggestions for the organisation of a vaccination programme. Finally, suggested responses to common patient misconceptions and frequently asked questions are included. The aim of this article is to harmonise the diagnosis of seasonal influenza and the approach of European general practitioners to seasonal influenza vaccination in order to better identify influenza outbreaks and to move towards reaching the target vaccination rate of 75% throughout Europe.
O EFEITO DAS MUDANÇAS CLIMÁTICAS NAS NECESSIDADES HÍDRICAS DO FEIJÃO-CAUPI NO CURU-PENTECOSTE UTILIZANDO O MODELO "ISAREG"

The irrigation management of the Curu-Pentecoste irrigation project (as in other irrigated areas of the Brazilian Northeast) is usually unaware of the actual water demands of the crops in the area, as well as unaware of possible impacts (on these needs) of climate changes. This study was aimed at quantifying the impact of the temperature rise predicted by the Intergovernmental Panel on Climate Change - IPCC, on the water demands of the irrigated cowpea crop in the Curu – Pentecoste irrigated area. The "software" "ISAREG. " was used to determine the NAC (water demands of the crop). With this software, it was calculated the
Multicoated and Folded Graph Neural Networks with Strong Lottery Tickets

The Strong Lottery Ticket Hypothesis (SLTH) demonstrates the existence of high-performing subnetworks within a randomly initialized model, discoverable through pruning a convolutional neural network (CNN) without any weight training. A recent study, called Untrained GNNs Tickets (UGT), expanded SLTH from CNNs to shallow graph neural networks (GNNs). However, discrepancies persist when comparing baseline models with learned dense weights. Additionally, there remains an unexplored area in applying SLTH to deeper GNNs, which, despite delivering improved accuracy with additional layers, suffer from excessive memory requirements. To address these challenges, this work utilizes Multicoated Supermasks (M-Sup), a scalar pruning mask method, and implements it in GNNs by proposing a strategy for setting its pruning thresholds adaptively. In the context of deep GNNs, this research uncovers the existence of untrained recurrent networks, which exhibit performance on par with their trained feed-forward counterparts. This paper also introduces the Multi-Stage Folding and Unshared Masks methods to expand the search space in terms of both architecture and parameters. Through the evaluation of various datasets, including the Open Graph Benchmark (OGB), this work establishes a triple-win scenario for SLTH-based GNNs: by achieving high sparsity, competitive performance, and high memory efficiency with up to 98.7\% reduction, it demonstrates suitability for energy-efficient graph processing.
An Assessment of ENSO-Induced Patterns of Rainfall Erosivity in the Southwestern United States

Abstract Microerosion processes due to the impact of raindrops on the soil (rainsplash) represent an important mechanism of detachment and removal of soil parcels. The annual and interannual patterns of rainsplash erosion are controlled by the variability of rainfall, vegetation cover, and land-use practice. This paper presents a study of the interannual variability of rainfall erosivity (which is an indicator of the erosive power of rainfall) due to winter precipitation in the southwestern United States and its connection to the El Nino–Southern Oscillation (ENSO). A remarkable degree of dependence was found between the values of winter erosivity and the Southern Oscillation index (SOI) in the months proceeding and during each winter. In general, it was observed that the erosive power of rainfall is stronger during El Nino years and weaker during the La Nina phase in the U.S. southwest, as is the rainfall itself. It was also observed that the erosivity and SOI are nonlinearly related. This dependence of .
New record of the Blue-spotted Cornetfish, Fistularia commer - sonii Rüppell, 1838 (Syngnathiformes Fistularidae), in the South-Western Mediterranean Sea

The recent caught of a male specimen of Blue-spotted Cornetfish, Fistularia commersonii Ruppell, 1838 (Syngnathiformes Fistularidae), near the coast of Portoscuso, Sardinia, Italy (South-Western Mediterranean Sea, 39°12.17' N / 8°22.44' E) is described. Morphometric and meristic data are reported.
Antimicrobial Susceptibility Pattern of Brucella Isolates from Abortion Cases in Animals in Northern India

Brucellosis is a common animal disease in India and many other neighboring countries and due to the non-culling policy of carrier cows, the problem is an ever-spreading zoonosis. To find the treatment options, the present study was undertaken to determine the antimicrobial sensitivity of 42 Brucella strains isolated from different animals to antibiotics and herbal antimicrobials. The study revealed the existence of multiple drug resistance among strains of B. melitensis as well as B. abortus . A total of 6, 25, 5, 3, 30, 9, 4, 30 and 37 strains were resistant to tetracycline, doxycycline, streptomycin, gentamicin, cotrimoxazole (sulphamethoxazole+trimethoprim), ciprofloxacin, chloramphenicol, azithromycin and erythromycin, respectively. All the B. melitensis and 55.6% of B. abortus strains were classified as MDR. All strains were sensitive to imipenem and tigecycline. Irrespective of species all Brucella strains were sensitive to ajowan ( Tachyspermum ammi ) oil, carvacrol, and cinnamaldehyde and 93.5% to cinnamon ( Cinnamomum verum ) oil indicating the potential of herbal antimicrobials for future alternative drug development.