Miracle-dz/UniFAR-FTUs huggingface dataset:
Impact of Sports Participation on Achievement of Clinically Relevant Outcomes 2 Years After ACL Reconstruction

Background: Clinically relevant threshold values associated with patient-reported outcome measures after orthopaedic procedures such as anterior cruciate ligament reconstruction (ACLR) are important for relating these scores to meaningful postoperative improvement. Purpose/Hypothesis: The purpose of this study was to determine the Patient Acceptable Symptom State (PASS) for the Patient-Reported Outcomes Measurement Information System Computer Adaptive Test (PROMIS-CAT) after ACLR. It was hypothesized that preoperative sport participation would have an impact on PASS achievement. Study Design: Case series; Level of evidence, 4. Methods: Included were consecutive patients who underwent primary assisted ACLR between January 4 and August 1, 2016. Patients were administered the PROMIS-CAT Physical Function (PF) and Pain Interference domains preoperatively and at a minimum 2 years postoperatively, with external anchor questions used to determine the PASS. Receiver operating characteristic (ROC) curves were constructed for the entire study population as well as separately for athletes and nonathletes to determine PROMIS PASS thresholds for each population. A previously published PROMIS-PF minimal clinically important difference was used to evaluate postoperative improvement. A post hoc multivariate nominal logistic multivariate analysis was constructed to assess the effects of preoperative patient characteristics on the likelihood of attaining both the minimal clinically important difference and PASS. Results: In total, 112 patients were included in the study, with 79 (71%) having recreational or higher levels of athletic participation. The PASS for the study population was 56.0 (area under the ROC curve, 0.86) and was unaffected by baseline PROMIS-PF scores but was affected by preoperative athletic participation (56.0 for athletes, 49.0 for nonathletes). A post hoc analysis found 57 patients (51%) achieved the PASS for the PROMIS-PF (cutoff, 56.0), but when the athlete and nonathlete thresholds were applied to their respective patient groups, 66% of athletes and 64% of nonathletes achieved the PASS postoperatively. The multivariate analysis found that sport participation (odds ratio, 6.2; P = .001) but not age, sex, body mass index, or preoperative PROMIS affected the likelihood of achieving the PASS on the PROMIS-PF. Conclusion: Preoperative athletic participation significantly affected the ability to achieve PASS.
Climate Change and the Exhaustion of Fossil Energy and Mineral Resources

The ongoing exhaustion of fossil fuels places a limit to the total amount of anthropogenic CO2 that will be emitted into the atmosphere and therefore constraints future global warming. Here we assess the implications of fossil fuels depletion on future changes of atmospheric CO2 concentration and global-mean temperature. We find that, despite the exhaustion of fossil fuels, future global warming will likely reach a dangerous level. Deliberate actions aiming at emissions reduction are needed to avoid dangerous climate change.
EVALUATION OF BRAKE-LAMP PHOTOMETRIC REQUIREMENTS

This research attempted to: (1) evaluate the luminance of current brake and presence lamps, (2) determine the relevant photometric parameter for brake lamps, and (3) determine minimum brake-lamp photometric requirements. Six studies were done: (1) average luminance values and photodensitometry were obtained to develop luminance maps for rear lamps of 40 automobiles; (2) equivalent luminance of set of stock lamps was derived for use in later studies. Equivalent luminance was derived from brightness matches between the stock lamps and lamps of same size and shape but of uniform luminance. (3) and (4) studies investigated minimum brake-lamp photometrics for signal detection under high levels of ambient illumination; (5) and (6) studies assessed the effect of lamp photometrics on the differentiation between brake and presence signals under low levels of ambient illumination. It is recommended that (1) luminous intensity be retained as the relevant photometric parameter of automobile brake lamps, and (2) 80 cd be retained as the mnimum brake-lamp luminous intensity.
Digitization in Skin Shade Matching for Maxillofacial Prostheses: A Systematic Review

Color matching of maxillofacial prostheses for the restoration of maxillofacial defects is an important factor for esthetic results. Various methods have been introduced for the accurate and reliable color matching of prostheses with the skin color of patients. A systematic review was conducted to search the existing literature on color-matching digital techniques for maxillofacial prostheses. An electronic literature search was conducted in PubMed/Medline, Scopus, and Web of Science from January 2000 to December 2022 using Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) guidelines. Two independent reviewers conducted the search. Eight articles that fulfilled the inclusion criteria after a full-text evaluation were included in this review. Most of these studies were published in prosthodontics journals and conducted in various countries around the world. A computerized color formulation system was used in three studies; a non-contact spectroradiometer (PR 705; Photo Research Inc., Chatsworth, CA) with a Xenon arc lamp was used in two studies; a mobile phone colorimeter was used in one study; additive manufacturing of 3D facial skin with a spectrophotometer was used in one study; and a recently introduced computerized method known as e-skin (Spectromatch, Bath, UK) was used in two studies. Most of these methods were accurate in color matching, except for the additive manufacturing system, which showed less accuracy, but good repeatability. Owing to a lack of sufficient studies, no method can be labeled as the best method for color-matching maxillofacial prostheses. The latest computerized method, the e-skin, can be used to achieve better accuracy and good color matching. However, further studies are required to validate the use of e-skin for precise color matching.
DEM-FEM coupling analysis of shot′s energy distribution and target′s residual stress of pneumatic shot peening

Pneumatic shot peening is a widely used surface strengthening method. During the peening process, shots often collide with each other, resulting in large energy loss and small compressive residual stress. In order to achieve the optimum compressive residual stress with as little energy loss as possible, firstly the collision mechanism of shots and the forming and coupling mechanism of the target’s residual stress are revealed, and then pneumatic shot peening is simulated by using DEM-FEM coupling model. Then, the effects of impact angle θ, initial shot velocity v 0, shot diameter d p, and mass flow rate r m on the percentage η of shots with different ratios of the impact velocity to initial shot velocity v m/v 0, the energy loss (EL), the energy transferred from shots to the target (ET), the residual energy (ER) and the compressive residual stress (RS) are investigated. The results show that as many random shots successively impact the target, the RS field induced by each shot couples with some adjacent RS fields induced by other shots, so that disperse RS fields are gradually transformed into a continuous RS layer with the compressive RS in the surface and the tensile RS in the subsurface. With the increase of θ and r m and with the decrease of v 0 and d p, the collision probability of shots increases, so EL also increases and η of shots with a large v m/v 0 decreases. While, ET increases with the increase of v 0 and d p, decreases with the increase of r m, and first increases and then decreases with the increase of θ. ET does not entirely determine but greatly affects the compressive RS field. So, the surface compressive RS and the maximum compressive RS first increase and then decrease with the increase of θ and r m, while the two parameters increase with the increase of v 0 and d p. The optimum parameters of shots are θ = 75°, v 0 = 60 m s−1, d p = 0.25 mm and r m = 2 kg min−1, in which ET reaches 45%, the surface compressive RS of S11 and S33 reach 512 MPa and 510 MPa respectively, and the maximum compressive RS of S11 and S33 reach 665 MPa and 746 MPa respectively.
Characteristics of patients with decompression illness at the hyperbaric polyclinic of Prof IGNG Ngoerah General Hospital Bali before the COVID-19 pandemic

Decompression illness (DCI) is an injury suffered by divers due to the formation of nitrogen bubbles in the bloodstream and tissues during or after a pressure drop in the surrounding environment when diving. Bali is one of the most famous diving spots in Southeast Asia and also has a Hyperbaric Oxygen Therapy (HBOT) center in Prof. IGNG Ngoerah General Hospital. This study aims to determine the characteristic of DCI patients at the Hyperbaric Polyclinic in Prof. IGNG Ngoerah General Hospital, Denpasar, Bali before the COVID-19 pandemic. A descriptive retrospective study has conducted by descriptive retrospective by collecting administrative data at the Hyperbaric Polyclinic of Prof. IGNG Ngoerah General Hospital in 2018-2019. The required examination data are demographic data, diver profiles, DCI characteristics, and the previous therapy. Data analysis using SPSS Version 24. Most DCI patients in this study were foreigner (88.1%), men (53.2%), normal BMI (37.3%), no prior history of disease (88.9%), diving depth >20 meters (n=79, 62.7%), average surface interval 101,184 minutes (30-1440 minutes), diving duration 1-3 hours (n=69.54.8%), DCI type 2 (58.7%) with major severity (57.9%). Of the overall patients, 14.3% rapid ascent, 2.4% panicked while diving, 10.3% made flights and 6.3% climbed after diving.
FACTORS AFFECT STOCK PRICES ON MANUFACTURING COMPANIES LISTED ON IDX BEFORE AND DURING COVID-19 PANDEMIC

This research aims to empirically examines the effect of Earning Per Share, Return On Assets, Debt to Equity Ratio, Quick Ratio, Dividend Payout Ratio, and Dividend Yield on the stock prices of manufacturing companies listed on IDX before and during COVID-19 pandemic, also empirically examines the differences on stock prices of manufacturing companies listed on IDX before and during COVID-19 pandemic. This research using 52 samples of manufacturing companies that listed on IDX for the 2019-2020 period. The 2019 data represent conditions before COVID-19 pandemic and the 2020 data represent conditions during COVID-19 pandemic. The results of this research are Earning Per Share and Dividend Payout Ratio effects significantly positive towards stock prices either before or during COVID-19 pandemic.
Sea level variability and coastal inundation over the northeastern Mediterranean Sea

ABSTRACT Sea level is a key element of global-scale climatic changes with significant coastal impacts. The northeastern Mediterranean Sea (Aegean, Ionian, and Cretan Seas: AICS) consists of extended low-lying coastal zones exposed to coastal inundation due to seawater level increases. The variability of the Sea Level Anomaly (SLA) in the AICS has been evaluated with the use of satellite-derived observations from 1993 to 2021. The general SLA trend over the AICS domain was 3.6 mm/year, which is higher than that of the overall Mediterranean Sea. The coastal inundation variability along the AICS coastline, specifically in 20 characteristic study areas, was investigated based on the long-term satellite-derived sea level observations, high-resolution land elevation data, and numerical simulations, conducted with a coastal inundation (CoastFLOOD) model. The coastal zones were categorized based on the frequency of occurrence and percentage coverage of flooding incidents during the 29-year period, while the interannual trends and the seasonality of inundated littoral and inland areas also showed intense spatial variation. High flooding levels occurred at coastal areas of either extended low-lying areas and/or high sea level elevations. The coastal zones were categorized based on a heuristic Coastal Inundation Hazard Index (CIHI: 1–5 ranking) that was determined by the occurrence frequency of severe floods (temporal component) and their impact area (spatial component). Our study findings provide vital information about the coastal inundation conditions and the respective hazard level of the AICS, useful to support enhanced coastal zone management for the improvement of coastal protection and decisions about coastal hazards’ mitigation.
Martian Bow Shock Oscillations Driven by Solar Wind Variations: Simultaneous Observations From Tianwen‐1 and MAVEN

The Martian bow shock stands as the first defense against the solar wind and shapes the Martian magnetosphere. Previous studies showed the correlation between the Martian bow shock location and solar wind parameters. Here we present direct evidence of solar wind effects on the Martian bow shock by analyzing Tianwen‐1 and MAVEN data. We examined three cases where Tianwen‐1 data show rapid oscillations of the bow shock, while MAVEN data record changes in solar wind plasma and magnetic field. The results indicate that the bow shock is rapidly compressed and then expanded during the dynamic pressure pulse in the solar wind, and is also oscillated during the IMF rotation. The superposition of variations in multiple solar wind parameters leads to more intensive bow shock oscillation. This study emphasizes the importance of joint observations by Tianwen‐1 and MAVEN for studying the real‐time response of the Martian magnetosphere to the solar wind.
PENGARUH PROMOSI KESEHATAN TERHADAP PENGETAHUAN DAN SIKAP DENGAN TINDAKAN PENCEGAHAN STUNTING OLEH KADER POSYANDU DI WILAYAH KERJA PUSKESMAS BAILANG KOTA MANADO

Stunting adalah kondisi dimana tinggi badan seseorang ternyata lebih pendek dibanding tinggi badan orang lain pada umumnya. Promosi kesehatan adalah upaya untuk meningkatkan kemampuan masyarakat melalui pembelajaran diri oleh dan untuk masyarakat agar mereka dapat mandiri dalam mengembangkan setiap kegiatan yang ada. Kader posyandu merupakan salah satu bentuk kemandirian masyarakat. Tugas kader dalam kegiatan posyandu sangat besar karena bukan hanya sebagai pemberi informasi kesehatan tetapi juga sebagai penggerak masyarakat untuk bisa hadir di posyandu. Penelitian ini bertujuan untuk mengetahui pengaruh promosi kesehatan terhadap pengetahuan dan sikap dengan tindakan pencegahan stunting oleh kader posyandu di Wilayah Kerja Puskesmas Bailang Kota Manado. Penelitian ini menggunakan rancangan eksperimen sungguhan (true eksperimen) yang menggunakan pre-test post-test dengan kelompok kontrol. Jumlah responden 30 kader posyandu yang dibagi menjadi tiga kelompok yaitu kelompok eksperimen a (penyuluhan) 10 kader, kelompok eksperimen b (penyuluhan dan leaflet) 10 kader dan kelompok kontrol (tidak diberikan intervensi) 10 kader. Kesimpulan ada pengaruh yang signifikan promosi kesehatan terhadap pengetahuan dan sikap dengan tindakan pencegahan stunting oleh kader posyandu pada kelompok eksperimen a dan kelompok eksperimen b dengan p-value 0.05. Kata kunci : Penyuluhan, Leaflet, Pengetahuan, Sikap, Tindakan Pencegahan Stunting ABSTRACT Stunting is a condition where someone’s height is shorter compare to others’ normal height. Health promotion is an effort to increase public’s abilities through self-learning by and for the society itself, hence, independence can established in developing every available activity. Volunteer framework is regarded as one of community independence practice. Its responsibility in integrated post service (posyandu) is highly important not only as information providers, but also as public motivators to take part in posyandu. This study aims to discover the impact of health promotion towards awareness and attitudes with stunting prevention actions by volunteer framework at Bailang Community Health Centre workplace in Manado. This study employs true experiment design using pre-test post-test with control group. The total of respondents were 30 Posyandu volunteers who were divided into three groups which are the experiment group a (counseling) 10 volunteers, the experiment group b (counseling and leaflet) 10 volunteers and control group (intervention is not given) 10 volunteers. Conclusion shows significant impacts of health promotion towards awareness and attitudes with stunting prevention actions by volunteer framework of integrated service post (posyandu) on experiment group a and group experiment b when given intervention with p-value 0.05 Keywords : stunting, counseling, leaflet, awareness, attitude, preventing action.
Strength and durability status of the Fagfog Quarzite from the Lower Nawakot Group, central Nepal Lesser Himalaya

Railways have played vital role in the development of many countries worldwide. Government of Nepal has already planned to establish various national and international railway networks within the nation. A substantial quantity of durable rock ballasts is required for building a sustainable railway network. Quartzites from central Nepal Lesser Himalaya can be a promising source to fulfill this requirement. Therefore, the quartzites from the stratigraphic unit Fagfog Quartzites of the Lower Nawakot Group located in Dhading District along the Kalu Pandey Highway have been assessed to determine physical, strength and durability characteristics of the ballasts. All quartzite ballasts obtained from the bedrocks were of Precambrian, medium-grained, bladed to prolate shaped, white to brownish white, crushed quartzites. Dry density and water absorption were respectively 2336-2641 kg/m3 and 0-2.5%. The bulk density varies from 1204 and 1387 kg/m3. Point load strength index varies from 2.04 to 11.55 MPa (medium strong to extremely strong). Aggregate Impact Value (AIV) and Aggregate Crushing Value (ACV) ranges from 14.85 to 22.77% and 15.51 to 22.17% respectively. Some 7% results of AIV and 20% of ACV results exceeded the established limiting value of 22%. The slake durability index (Id5) ranges from 95.19 and 99.11%, whereas Id2 ranged between 96.94 and 100%, which shows that 80% of the samples have very high slake durability whereas remaining 20% exhibit high slake durability. There was no significant change in slake durability index from the second to the fifth cycles. Los Angeles Abrasion Value (LAAV) varies from 12.07 to 31.34% and Sulphate Soundness Value (SSV) varies within a limited range of 0.20 and 4.59%. Conclusively, the comprehensive evaluation suggests that the quartzite ballast from the Fagfog Quartzite source display favourable qualities in terms of point load, crushing and impact strengths and durable against abrasion, slaking and frosting. Thus, the quartzites from Fagfog Quartzite hold significant potential as a suitable rock type for railway track ballasts.
Studies on aonla (Emblica officinalis Gaertn) nectar and biochemical changes with advancement of storage period.

With a view to develop value added products, nectar using fruits of cultivar NA-7 with various recipes was prepared. The prepared nectar was kept at ambient condition for storage study. The nectar remained acceptable upto 240 days at ambient condition. The nectar prepared from T 3 (20 per cent juice, 20 per cent TSS and 0.3 per cent acidity) recorded maximum organoleptic score than other recipe treatments. The biochemical composition in aonla nectar prepared from T 6 (35 per cent juice, 20 per cent TSS and 0.3 per cent acidity) had the maximum retained acidity, TSS, total sugar, reducing sugar than rest of the recipes and their increasing trend with advancement of storage period upto 240 was recorded under ambient condition. On the other hand, the nectar prepared with T 6 (35 per cent juice, 20 per cent TSS and 0.3 per cent acidity) had maximum ascorbic acid, non-reducing sugar, TSS / acidity ratio, pH and organoleptic score and these traits showed decreasing trend with advancement of storage period upto 240 days under ambient condition. The microbial population increased invariably with successive advancement of storage period irrespective of recipe treatments used. Minimum bacterial counts, yeast counts and mould counts was noted under T 3 (20 per cent juice, 20 per cent TSS and 0.3 per cent acidity). The nectar prepared from T 3 (20 per cent juice, 20 per cent TSS and 0.3 per cent acidity) had the maximum benefit: cost ratio, good sensory evaluation score and high nutritional quality.
Oncogenic Targets Regulated by Tumor-Suppressive miR-30c-1-3p and miR-30c-2-3p: TRIP13 Facilitates Cancer Cell Aggressiveness in Breast Cancer

Simple Summary Two passenger strand microRNAs (miRNAs), miR-30c-1-3p and miR-30c-2-3p, were identified as tumor-suppressive miRNAs in breast cancer (BrCa) cells. Seven genes (TRIP13, CCNB1, RAD51, PSPH, CENPN, KPNA2, and MXRA5) were putative targets of these miRNAs, and their expression was closely involved in BrCa molecular pathogenesis. Among these targets, inhibition of TRIP13 significantly suppressed aggressive phenotypes of BrCa cells. Abstract Accumulating evidence suggests that the miR-30 family act as critical players (tumor-suppressor or oncogenic) in a wide range of human cancers. Analysis of microRNA (miRNA) expression signatures and The Cancer Genome Atlas (TCGA) database revealed that that two passenger strand miRNAs, miR-30c-1-3p and miR-30c-2-3p, were downregulated in cancer tissues, and their low expression was closely associated with worse prognosis in patients with BrCa. Functional assays showed that miR-30c-1-3p and miR-30c-2-3p overexpression significantly inhibited cancer cell aggressiveness, suggesting these two miRNAs acted as tumor-suppressors in BrCa cells. Notably, involvement of passenger strands of miRNAs is a new concept of cancer research. Further analyses showed that seven genes (TRIP13, CCNB1, RAD51, PSPH, CENPN, KPNA2, and MXRA5) were putative targets of miR-30c-1-3p and miR-30c-2-3p in BrCa cells. Expression of seven genes were upregulated in BrCa tissues and predicted a worse prognosis of the patients. Among these genes, we focused on TRIP13 and investigated the functional significance of this gene in BrCa cells. Luciferase reporter assays showed that TRIP13 was directly regulated by these two miRNAs. TRIP13 knockdown using siRNA attenuated BrCa cell aggressiveness. Inactivation of TRIP13 using a specific inhibitor prevented the malignant transformation of BrCa cells. Exploring the molecular networks controlled by miRNAs, including passenger strands, will facilitate the identification of diagnostic markers and therapeutic target molecules in BrCa.
INTELLIGENT PREDICTION OF THE FROST RESISTANCE OF HIGH-PERFORMANCE CONCRETE: A MACHINE LEARNING METHOD

Frost resistance in very cold areas is an important engineering issue for the durability of concrete, and the efficient and accurate prediction of the frost resistance of concrete is a crucial basis for determining reasonable design mix proportions. For a quick and accurate prediction of the frost resistance of concrete, a Bayesian optimization (BO)-random forest (RF) approach was used to establish a frost resistance prediction model that consists of three phases. A case study of a key national engineering project results show that (1) the RF can be used to effectively screen the factors that influence concrete frost resistance. (2) R2 of BO-RF for the training set and the test set are 0.967 and 0.959, respectively, which are better than those of the other algorithms. (3) Using the test data from the first section of the project for prediction, good results are obtained for the second section. The proposed BO-RF hybrid algorithm can accurately and quickly predict the frost resistance of concrete, and provide a reference basis for intelligent prediction of concrete durability.