Miracle-dz/UniFAR-FTUs huggingface dataset:
Planar and Quasi Planar Simultaneous Geometric Embedding (cid:2)

A simultaneous geometric embedding ( SGE ) of two planar graphs G 1 and G 2 with the same vertex set is a pair of straight-line planar drawings Γ 1 of G 1 and Γ 2 of G 2 such that each vertex is drawn at the same point in Γ 1 and Γ 2 . Many papers have been devoted to the study of which pairs of graphs admit a SGE, and both positive and negative results have been proved. We extend the study of SGE, by introducing and characterizing a new class of planar graphs that makes it possible to immediately extend several positive results that rely on the property of strictly monotone paths. Moreover, we introduce a relaxation of the SGE setting where Γ 1 and Γ 2 are required to be quasi planar (i.e., they can have crossings provided that there are no three mutually crossing edges). This relaxation allows for the simultaneous embedding of pairs of planar graphs that are not simultaneously embeddable in the classical SGE setting and opens up to several new interesting research questions.
Supplementary Web Appendix for: Censoring Unbiased Regression Trees and Ensembles

References to Sections preceded by “S. ” and figures, tables, theorems and equations preceded by “S-” are internal to this supplement; all other references refer to the main paper. Example R code implementing the CURE−L2 algorithms in the case of the nonparametric bootstrap for the Copenhagen Stroke study is also included in a separate file as additional supplementary material. Other code is available upon request from Dr. Jon Steingrimsson. The Supplementary Web Appendix is organized as follows.
PCR-Based Detection of Bacillus anthracis in Formalin-Fixed Tissue from a Patient Receiving Ciproﬂoxacin

We demonstrate that Bacillus anthracis may be detected from a formalin-ﬁxed, parafﬁn-embedded biopsy specimen, even after the patient has received antibiotic treatment. Although traditional PCR methods may not be sufﬁciently sensitive for anthrax detection in such patients, cycle numbers can be increased or PCR can be repeated by using an aliquot from a previous PCR as the template. Bacillus anthracis , the causative agent of anthrax, postulated to be a likely agent biological physical properties its virulence
Females beneﬁt from mating with different males in the scorpionﬂy Panorpa cognata

The adaptive signiﬁcance of female polyandry has become a recurrent subject of recent theoretical and empirical research. It has been argued that in addition to direct beneﬁts, such as nuptial gifts or an adequate sperm supply, females may gain genetic beneﬁts from mating with different males. Females of the scorpionﬂy Panorpa cognata mate with several males during their lifetime. In an experiment designed to rule out any direct nutritional beneﬁt of multiple matings, I found that polyandrous females that mated with two different males achieved a signiﬁcantly higher egg-hatching success than monandrous females that mated twice with the same male. However, individual males did not trigger the same response in different females as the egg-hatching success of different females that mated with one and same male did not correlate. The results, thus, do not conform to predictions from hypotheses assuming that genetic beneﬁts of polyandry are inﬂuenced by the intrinsic genetic quality of males. The results are, however, consistent with the genetic incompatibility hypothesis. Nevertheless, substances from different males transferred during copulation may synergistically affect zygote viability. Furthermore, I discuss why paternity studies can only explicitly test the genetic incompatibility hypothesis if there are a priori expectations of female-male genome compatibilities. [Behav 17:435–440 (2006)]
Sociodemographic Correlates of Suicidal Ideation among College Students of Manipur

Background: Suicide is the second leading cause of death worldwide for individuals aged 15–29 years, and college students are the subpopulations who are receiving less attention. The suicide crisis in India’s school and colleges is worsening, reaching the highest suicide rate in the world among youth standing at 35.5% per 100,000. Suicide reported every 15 minutes in India, one is committed by a youth in the age group of 15-29 years. The environmental and social factors unique to college students includes social, academic, psychological, and existential. This major life transition as well as specific risk factors may exacerbate existing psychological difficulties or trigger new ones that can ultimately lead to suicide. Methodology: Aims: Present study has been under taken with the aim to identify socodemographic correlates of suicidal ideation among college students. Sample: The surveying approach under the descriptive method was adopted. 200(140 females and 60 males) undergraduate students within the age range of 18-26years were selected randomly from 3 different colleges of Imphal-west district of Manipur through multistage sampling method and informed consent was taken from the participants. Tools: Semi structured and self-prepared performato collect information about socodemographic variables and Adult Suicidal Ideation Questionnaire (ASIQ) to assess the frequency of occurrence of suicidal ideation within the past month were utilized in the present study. Results and conclusion: Results indicated the presence of suicidal ideation among college students. Among the 200 participants, 10% participants were having suicidal ideation of which 8 male and 12 female participants exhibited suicidal ideation representing 10% of the 200 participants. Age and educational level were the two important variables that statistically correlated with suicidal ideation among the participants. It can be concluded that better understanding of the risk factors leading to suicide would focus on potential target for early intervention for college students.
BMN Operators for = 1 superconformal Yang-Mills theories and associated string backgrounds

: We study a class of near-BPS operators for a complex 2-parameter family of N = 1 superconformal Yang-Mills theories that can be obtained by a Leigh-Strassler deformation of N = 4 SYM theory. We identify these operators in the large- N and large R charge limit and compute their exact scaling dimensions using N = 1 superspace methods. From these scaling dimensions we attempt to reverse-engineer the light-cone worldsheet theory that describes string propagation on the Penrose limit of the dual geometry.
3D Segmentation for Super-Resolution Imaging of Bacterial Biofilms

The emergence of super-resolution microscopy using lattice light sheet is enabling the exploration of structure and function in living tissues such as bacterial biofilms that have mysterious interconnections and organization. Such a technique overcomes the diffraction limit in traditional confocal microscopy, which also provides non-phototoxic three-dimensional images at resolutions ten times smaller than that provided by traditional light microscopy. Unfortunately, the standard tools used in the image analysis community to perform segmentation and other higher-level analyses cannot be applied naïvely to these data. In this thesis, Bact-3D is presented for segmenting super-resolution images of multi-leveled, living bacteria cultured in vitro. It incorporates a novel initialization approach that exploits the geometry of the bacterial cells as well as iterative local level set evolution that is tailored to the biological application. In experiments where segmentation is used as precursor to cell detection, the Bact-3D matches or improves upon the Dice score and mean-squared error of three existing methods, while yielding a substantial improvement in cell detection accuracy. In addition to providing improvements in performance over the state-of-the-art, this report also characterizes the tradeoff between imaging resolution and segmentation quality. Evaluation of the algorithm complexity and operating times of Bact-3D as well as alternative solutions are also discussed. Improvements based on Bact-3D method are proposed to increase the applicability in extended datasets, where bacteria are randomly distributed and densely overlapped. The improved methodology ensures the locality i of 3D level set based active surface model, which is achieved by proposing intuitive distance velocity field (DVF), of the level set evolution. Preliminary experimental results that compare the performance of improved approach with two existing methods exhibit competitive advantage in segmenting neighboring cells. Comprehensive application of combining geometric and parametric segmentation techniques on these challenging datasets is also proposed for future work.
catalysts Improved Sulfur Resistance of COMMERCIAl V 2 O 5 -WO 3 /TiO 2 SCR Catalyst Modiﬁed by Ce and Cu

: The accumulation of NH 4 HSO 4 leads to the deactivation of commercial V 2 O 5 -WO 3 /TiO 2 catalyst (VWTi) in practical application. The commercial catalyst is modiﬁed with 0.3 wt. % Ce and 0.05 wt. % Cu (donated as VWCeCuTi), and its sulfur resistance is noticeably improved. After loading 20 wt. % NH 4 HSO 4 , the NO x conversion of VWCeCuTi-S remains 40% at 250 ◦ C, higher than that of VWTi-S (25%). Through a series of characterization analyses, it was found that the damaged surface areas and acid sites are the key factors for the deactivation of S-poisoned samples. However, surface-active oxygen and NO adsorption are increased by NH 4 HSO 4 deposition, and the L–H mechanism is promoted over S-poisoned samples. Due to the interaction between V, Ce and Cu, the surface-active oxygen over VWCeCuTi-S is increased, and then NO adsorption is promoted. In addition, VWCeCuTi-S obtains a higher V 5+ ratio and a better redox property than VWTi-S, which in turn accelerates the NH 3 -SCR reaction. More NO adsorption and encouraged reaction contribute to the better sulfur resistance of VWCeCuTi.
Study on the Use of Cellular Respiration as a Surrogate Biomarker in Drug Development

Cellular respiration (mitochondrial O 2 consumption or oxidative phosphorylation) is the process of delivering nutrients and O 2 to the mitochondria, oxidation of reduced metabolic fuels, passage of electrons to O 2 , and synthesis of ATP. These vital processes can serve as surrogate biomarkers for identifying cellular responses to drugs. This study investigated divergent compounds to learn whether their modes-of-action or adverse events could be linked to altered cellular bioenergetics. Small tissue fragments were collected from various organs of C57BL/6 mice in RPMI with and without designated drugs. Cellular respiration was then measured with the aid of a phosphorescence O 2 analyzer, using Pd (II) complex of meso -tetra-(4-sulfonatophenyl)-tetrabenzoporphyrin as an O 2 probe. The phosphoinositide 3-kinase/mammalian target of rapamycin (Pi3K/mTOR) inhibitor GSK2126458 (50nM) repressed heart cellular respiration ( p <0.001). This finding is consistent with the role of Pi3K/PTEN/Akt/mTOR pathway in cellular metabolism including insulin-dependent glucose uptake. The β 2 -adrenergic receptor agonist salbutamol (29 µM) and the bronchodilator magnesium sulphate (20mM) both inhibited lung cellular respiration ( p ≤0.006). The N-methyl-D-aspartate receptor antagonist ketamine (210 to 1,050 µM) had no significant effect on forebrain cellular respiration ( p ≤0.132). Although valproate induced histologic liver abnormalities, a therapeutic concentration of the drug (600 µM) had no effect on hepatocyte respiration ( p =0.916). Similarly, the hepatotoxic drug azidothymidine (a nucleoside reverse transcriptase inhibitor; 100 µM) had no effect on hepatocyte respiration ( p =0.297). Thus, cellular respiration can sense the activity and toxicity of some drugs. This analytical tool needs to be incorporated in drug development as a pharmacodynamic measure in targeted and off-targeted tissues.
Production and Characterization of Bacillus thuringiensis Cry1Ac-Resistant Cotton Bollworm Helicoverpa zea (Boddie) (cid:1)

Laboratory-selected Bacillus thuringiensis -resistant colonies are important tools for elucidating B. thu- ringiensis resistance mechanisms. However, cotton bollworm, Helicoverpa zea , a target pest of transgenic corn and cotton expressing B. thuringiensis Cry1Ac (Bt corn and cotton), has proven difﬁcult to select for stable resistance. Two populations of H. zea (AR and MR), resistant to the B. thuringiensis protein found in all commercial Bt cotton varieties (Cry1Ac), were established by selection with Cry1Ac activated toxin (AR) or MVP II (MR). Cry1Ac toxin reﬂects the form ingested by H . zea when feeding on Bt cotton, whereas MVP II is a Cry1Ac formulation used for resistance selection and monitoring. The resistance ratio (RR) for AR exceeded 100-fold after 11 generations and has been maintained at this level for nine generations. This is the ﬁrst report of stable Cry1Ac resistance in H . zea . MR crashed after 11 generations, reaching only an RR of 12. AR was only partially cross-resistant to MVP II, suggesting that MVP II does not have the same Cry1Ac selection pressure as Cry1Ac toxin against H . zea and that proteases may be involved with resistance. AR was highly cross-resistant to Cry1Ab toxin but only slightly cross-resistant to Cry1Ab expressing corn leaf powder. AR was not cross-resistant to Cry2Aa2, Cry2Ab2-expressing corn leaf powder, Vip3A, and cypermethrin. Toxin-binding assays showed no signiﬁcant differences, indicating that resis- tance was not linked to a reduction in binding. These results aid in understanding why this pest has not evolved B. thuringiensis resistance, and highlight the need to choose carefully the form of B. thuringiensis protein used in experiments.
TITLE: Polyandry pays off: The effects of multiple mating and number of fathers on morphological traits and survival in clutches of nesting green turtles at Tortuguero

Despite the long debate of whether or not multiple mating benefits the offspring, studies still show contradicting results. Multiple mating takes time and energy. Thus, if females fertilize their eggs with a single mating, why to mate more than once? We investigated and inferred paternal identity and number of sires in 12 clutches (240 hatchlings) of green turtles ( Chelonia mydas ) nests at Tortuguero, Costa Rica. Paternal alleles were inferred through comparison of maternal and hatchling genotypes, and indicated multiple paternity in at least 11 of the clutches (92%). The inferred average number of fathers was three (ranging from 1 to 2 ! 5). This in returns suggests that most females successfully got fecundated by at least three males. Moreover, regression analyses were used to investigate for correlation of inferred clutch paternity with morphological traits of hatchlings fitness (emergence success, length, weight and crawling speed); and size of the mother; and an environmental variable (incubation temperature). We suggest and propose two different comparative approaches for evaluating morphological traits and clutch paternity, in order to infer greater offspring survival. First, clutches coded by the exact number of fathers and second by the exact paternal contribution (fathers who gives greater proportion of the offspring per nest). We found significant differences ( P < 0.05) in clutches coded by the exact number of fathers for all morphological traits, where a tendency of higher values in offspring sired by two to three fathers was found. The second approach analysing the paternal contribution showed no significant difference ( P > 0.05) for any of the traits. The main conclusion is that multiple mating analysed by the exact number of inferred fathers significantly affects the survival of the offspring regardless of morphological trait measured.
D R A F T Signs of local adaptation and phenotypic plastic response to elevation shifted between environmental backgrounds in Snapdragon plants

Multiple environmental drivers can shape the plastic and microevolutionary adaptive responses of plants. Yet experimental studies on local adaptation and phenotypic plasticity rarely investigate how different backgrounds might interact and modify the signature patterns of these mechanisms. Here, we evaluated local adaptation and plasticity in response to elevation in two Snapdragon plant subspecies ( Antirrhinum majus striatum and A. m. pseudomajus ) by using common garden experiments at different elevations. We tested whether the phenotypic signatures of plasticity and local adaptation recorded in an open habitat were similar between subspecies and maintained when the experiment was replicated onsite under the shade of understory vegetation. Our results showed that population genetic divergence in germination-related traits was suggestive of a pattern of local adaptation to elevation under regular sunlight in A. m. striatum , but not in A. m. pseudomajus . They also revealed potentially neutral or adaptive plastic responses to elevation for these traits. The magnitude of plastic responses was stronger than trait genetic divergence. Under understory shade, phenotypic patterns were different and suggested maladaptive or neutral responses to elevation. Our ﬁndings imply that the genetic and plastic adaptive signatures of elevation cannot be inferred without taking into account the variability of the environmental background. They also imply that selection mechanisms linked to germination vary across heterogeneous environments in Snapdragon plants. Forecasting the ability of plants to adapt to environmental changes based on common garden and reciprocal transplant experiments must account for the multivariate nature of the environment.
Semi-analytical solution for soil-constrained vibration of subsea free-spanning pipelines

ABSTRACT Apart from being induced by internal and external flow, vibration of free-spanning pipelines is also constrained by the soil that supports the span on both ends. A wake oscillator model is chosen to describe the vortex shedding acting on the pipeline, and the soil spring is adopted to describe the pipe–soil interaction at the span shoulders. A semi-analytical solution – the generalised integral transform technique (GITT) – is used to study the dynamic response of free-spanning submarine pipelines. With this method, the coupled fluid-structure system of partial differential equations is transformed into a system of second-order ordinary differential equations in temporal variable. Parametric studies are carried out to analyse the influence of different internal and external flow velocities, and different soil stiffness. GITT is proved to be a fast and accurate approach for analysing the dynamic response of free-spanning submarine pipelines considering the influence of the current and the internal flow, as well as the effect of the soil.
Clinical Beneﬁts of Hepatic Arterial Infusion Chemotherapy for Advanced Hepatocellular Carcinoma

: Recent success of systemic therapeutic agents, including combination immunotherapy, could promote a change in the treatment strategy in patients with advanced hepatocellular carcinoma (HCC). Although hepatic arterial infusion chemotherapy (HAIC) is a treatment option for advanced HCC in Japan, it is not recommended by other guidelines. We discuss the clinical beneﬁts of HAIC compared to sorafenib. The clinical beneﬁts of HAIC are as follows: (1) even a patient with Child– Pugh B HCC (7 or 8 points) is a candidate for HAIC (2) Child–Pugh scores barely decline with the use of HAIC compared with sorafenib (3) HAIC is highly effective in patients with vascular invasion compared with sorafenib; and (4) survival in patients receiving HAIC may not be associated with skeletal muscle volume. In contrast, the disadvantages are problems related with the reservoir system. HAIC has clinical beneﬁts in a subpopulation of patients without extrahepatic metastasis with Child–Pugh A HCC and vascular invasion (especially primary branch invasion or main portal vein invasion) or with Child–Pugh B HCC.
RELATIONSHIPS AMONG SOME NOTIONS OF BIVARIATE DEPENDENCE

Abstract : A random variable T is left tail decreasing in a random variable S if P(T or = t divides S or = s) is non-increasing in s for all t, and right tail increasing in S if P(T t divides S s) is non-decreasing in s for all t. We show that either of these conditions implies that S,T are associated, i.e. Cov(f(S,T), g(S,T)) or = 0 for all pairs of functions f,g which are non- decreasing in each argument. No two of these conditions for bivariate dependence are equivalent. Applications of these and other conditions for dependence in probability, statistics, and reliability theory are considered in Lehmann (1966) Ann. Math. Statist. and Esary, Proschan, and Walkup (1966) Boeing documents D1-82-0567, D1-82-0578.
Suppression of Cytochrome P450 2E1 Promoter Activity by Interferon- (cid:1) and Loss of Response Due to the (cid:1) 71G (cid:2) T Nucleotide Polymorphism of the CYP2E1*7B Allele

The CYP2E1*7B allele is defined by two nucleotide sequence polymorphisms, (cid:1) 71G (cid:2) T and (cid:1) 333T (cid:2) A. The CYP2E1 promoter sequence flanking the (cid:1) 71G nucleotide is consistent with a (cid:1) -interferon activated sequence. Inflammation and interferon (IFN)- (cid:1) suppress expression of CYP2E1 in vivo; however, the exact mechanism is not known. The objectives of this study were to determine whether the CYP2E1 promoter is regulated by IFN- (cid:1) and to examine the influence of the nucleotide substitutions on this function. Treatment of HepG2 cells with IFN- (cid:1) , after transient transfection with a luciferase reporter gene bear- ing the native CYP2E1 ( (cid:1) 71G) promoter sequence resulted, in a dose-dependent reduction of luciferase activity. In contrast, no suppression was observed in cells transfected with the *7B allele promoter ( (cid:1) 333A and (cid:1) 71T) nor a CYP2E1 plasmid containing only the (cid:1) 71T polymorphism. These data indicate that IFN- (cid:1) suppresses native CYP2E1 promoter activity and that the (cid:1) 71G is critical for this response.
R THE EffECTS of DiffEREnT fungiCiDES on THE ViAbiliTy of EnTomopATHogEniC nEmAToDES Steinernema feltiae (filipjEV), S. carpocapsae WEiSER, AnD Heterorhabditis downesi SToCk, gRiffin & buRnEll (nEmAToDA: RHAbDiTiDA) unDER lAboRAToRy ConDiTionS

strains To increase our knowledge on the susceptibility of entomopathogenic nematodes (EPN) species to agrochemicals, the compatibility of the infective juveniles (IJ) of the entomopathogenic nematodes Steinernema feltiae , S. carpocapsae , and Heterorhabditis downesi with 15 chemical fungicides was investigated under laboratory conditions. The effect of direct IJ exposure to fungicides for 24 h was tested in a petri dish at 15, 20, and 25 ºC. The results showed that the compatibility of S. feltiae with azoxystrobin was high, and similar findings were obtained for S. carpocapsae (strain C67) and all of the tested fungicides, except for tebuconazole + spiroxamine + triadimenol, maneb, dinocap, and copper (II) hydroxide + metalaxil-M. Nematode H. downesi (strain 3173) suffered the highest mortality rate when infective juveniles were mixed with tebuconazole + spiroxamine + triadimenol. The integration of the aforementioned agents into a pest management program is also discussed. , Steinernema carpocapsae , Steinernema feltiae , viability.