Miracle-dz/UniFAR-FTUs huggingface dataset:
Risk Management and First Aid Knowledge of Trekkers in Nepal

Background: Trekking in Nepal is popular and generally safe. However preventable trekking injuries and deaths are often the result of poor risk managementand lack of skills – i.e. acute mountain sickness (AMS) and specific First Aid (FA). Shlim and Gallie’s reviews in 1992 and 2004 of trekking deaths here found a fivefold higher risk for fatal outcomes in organized trekking tours (OT) compared to independently organised trekkers (IT), including preventable deaths (i.e. AMS). Our survey sought to identify the AMS, FA and risk management knowledge/skills of OT and IT whilst trekking in Nepal. Methods: Based on previous pilot studies at the Khumbu region in Nepal, and on risk management information provided by leading German trekking operators, a survey was conducted using two questionnaires: one each for OT and IT.The study site was Manang (3,500m) in Annapurna region, Nepal. All trekkers passing through this site who volunteered their participation were included. For evaluation descriptive statistical methods and non-parametric tests were used. Results: 442 questionnaires were completed (155 OT; 287 IT). Mean agewas 36.4 +/– 12.0y and 61% were male. Mountaineering experience was low and FA training was scarce in both groups. IT (92.7%) followed acclimatization recommendations and 59.2% carried AMS medication, compared respectively to OT at 63.2% and 25.2%. Only 27.1% of OT had repatriation plans for a medical emergency. Conclusions: Most of OT and IT were inexperienced in mountaineering and in mountain emergencies. The preparedness of OT overall was inadequate and over-reliant on the organisers whose skills may also be inadequate when responding to an emergency. Responsible trekking should require that more than one person in a group have adequate, up-to-date riskassessment/management and FA skills specific to the trek, and in particular an understanding of altitude profile, AMS, and individual abilities.
Progressive collapse of moment resisting steel framed buildings quantitative analysis based energy approach

of Dissertation Presented to the Graduate School of the University of Florida in Partial Fulfillment of the Requirements for the Degree of Doctor of Philosophy PROGRESSIVE COLLAPSE OF MOMENT RESISTING STEEL FRAMED BUILDINGS QUANTITATIVE ANALYSIS BASED ENERGY APPROACH By Stefan Tadeusz Szyniszewski May 2009 Chair: Theodor Krauthammer Major: Civil Engineering An energy based, quantitative analysis of collapse propagation in steel framed buildings was developed in this work. Column buckling energy was proposed as a necessary condition to initiate the collapse (but it is not a sufficient). The column failure energy was introduced and verified as the sufficient collapse criterion. This study demonstrated that energy based analysis and energetic failure criteria facilitate understanding of collapse propagation and reveal the underlying mechanisms during the collapse arrest or propagation. Simulations of structural response to the sudden removal of key structural member(s) have been carried out for a number of moment resisting steel frames and steel framed buildings. The modeling aspects (e.g. retrieving reliable structural information, probabilistic geometric inaccuracies, and material models) are presented. Kinematic and energetic results with limited experimental validation are elaborated. An easy to use energy based analysis of collapse propagation has been developed and clearly explained in this study.
Surgical management in phyllodes tumors of the breast: a systematic review and meta-analysis.

Background Information is still controversial in the studies regarding the current optimal surgical management of phyllodes tumors (PTs) of the breast. Local recurrence (LR) may occur with an upgraded in the pathological grade, influencing the prognosis of patients with PT. This systematic review and meta-analysis aimed to investigate the association of LR risk with margin status and margin width which could have significant implications on the surgical management of PT. Methods Independent and comprehensive searches were performed by two authors through five databases including PubMed, Medline, Embase, ScienceDirect and Cochrane Library from January 1990 to October 2021. Studies investigating the association between margin width, margin status and LR rates were considered for inclusion. Study quality was evaluated using the Newcastle-Ottawa Scale (NOS). Meta-analysis was performed using RevMan5.3 software, and statistical heterogeneity was assessed using the Chi-square test and quantified using the I2 statistic. Visual inspection of funnel plots was used to judge publication bias. Results A total of 34 articles were included in this article, all of which with NOS scores above 5. Regardless of the PT grade, positive margin significantly increased the risk of LR [odds ratio (OR) 3.64, 95% confidence interval (CI): 2.60-5.12]. No significant difference was found in the risk of LR between the margins <1 and ≥1 cm (OR 1.39, 95% CI: 0.67-2.92). For benign and borderline PTs, there were no significant differences of the LR risk between breast-conserving surgery (BCS) and mastectomy (benign OR 0.68, 95% CI: 0.12-3.78; borderline OR 1.14, 95% CI: 0.29-4.51). While the LR risk was significantly increased by BCS for malignant PT (OR 2.77, 95% CI: 1.33-5.74). Discussion Different surgical management strategies should be considered for different PT grades. BCS was a feasible option and margins <1 cm was not significantly associated with LR risk for all grade of PT. After BCS, benign PT with positive margin could adopt the "wait and watch" strategy with regular follow-up, while borderline and malignant PTs were expected to underwent re-excision to ensure negative margins. More studies are still needed to clarify and update the existing conclusions and improve the prognosis of PT patients.
Microbes, memory, and moisture: predicting microbial moisture responses and their impact on carbon cycling

1. Soil moisture is a major driver of microbial activity and thus, of the release of carbon (C) into the Earth's atmosphere. Yet, there is no consensus on the rela-tionship between soil moisture and microbial respiration, and as a result, moisture response functions are a poorly constrained aspect of C models. In addition, models assume that the response
REMOTE STUDY AND DECONSUMPTION – SUSTAINABLE MOBILITY VERSUS (UN)NECESSARY UNIVESITY COMMUTING

The remote study was one of the many restrictions implemented during the COVID-19 pandemic. It resulted in a deconsumption of university commuting which, together with telecommuting, could be considered as a means to implement a sustainable mobility policy. Within this context, this paper investigates student's perceptions of the advantages and disadvantages of daily travel before online learning started with a focus on the resultant satisfaction from the use of given means of transport. In this context, we examined the potential for developing more sustainable mobility and possibilities for further deconsumption of transport processes. This was based on the results of a preliminary survey the author conducted online among students of two public universities in Poland. The results obtained, revealed that the respondents associated commuting to university with more advantages than disadvantages. However, these perceptions differed dependent on the most frequently used transport mode. Car users hardly benefited from commuting compared to other transport users and were the group least likely to resign from individual motorisation. Pedestrians and cyclists perceived the most benefits and were most satisfied. In general, students expected to continue commuting using the transport modes they used prior to the pandemic. Nevertheless, when students were asked about their “dream transport mode” which enabled the possibility for deconsumption of commuting by way of cheap and commonly available teleportation, the private car turned out to be a better option than teleportation among students commuting either by car or by urban public transport. In such a hypothetical situation, only car users and active commuters were not prepared to change their transport behaviour.
Convergence and vicariance: speciation of chameleons in the Cape Fold Mountains, South Africa, and the description of three new species of Bradypodion Fitzinger, 1843

ABSTRACT The mechanisms that underpin ecological speciation, morphological convergence and the evolution of ecological morphotypes (ecomorphs) in squamates have allowed for a better appreciation of the speciation process in chameleons. In particular, attention has been drawn to several populations of chameleons (Sauria, Chamaeleonidae, Bradypodion) from the Cape Fold Mountains, South Africa. Previous work suggested that these populations are genetically divergent, but with strong similarities in phenotype. Using an integrative taxonomic approach that accounts for genetic diversity, habitat and morphology, three of these populations are described as species. One population is from an isolated forest patch and is genetically different at the species level, but morphologically similar to Bradypodion damaranum (Boulenger, 1887) from forested areas in the Knysna region. Although not sister species, the two are in the same clade and probably diverged through vicariance of the forest. Two other populations are from fynbos habitat in adjacent mountain ranges (Tsitsikamma/Langkloof/Kouga mountains and Baviaanskloof Mountains) and are also morphologically similar, but genetically divergent at the species level. These two species are not sister taxa and are not in the same clade yet have a virtually identical phenotype presumably as the result of convergent evolution for the fynbos habitat. Within the context of morphological taxonomy, these populations have been difficult to evaluate. However, when viewed in the context of ecological speciation, convergence and morphological conservatism, the species boundaries are apparent, allowing for them to be described as new taxa.
Awareness of the benefits of ginger use among students of Nigeria army school of education, Sobi-Ilorin, Kwara State

The objective of this study was to determine the level of awareness, knowledge of benefits and use of ginger among the students of the Nigerian Army School of Education (NASE), Sobi-Ilorin Kwara State. The descriptive survey design was used to elucidate the awareness, knowledge of benefits and practice of ginger use. The population was all 350 students of NASE, Ilorin. They were purposively selected, from which 337 validly participated. The instrument for data collection was a validated researcher structured questionnaire. Test retest reliability was conducted and PPMC coefficient (r = 0.72) was obtained. Frequency and percentage were used for demographic data while t-test was used for testing the hypotheses at 0.05 alpha level. The result revealed that NASE, Ilorin students were highly aware of ginger, 312 (92.6%). There was significant difference between soldiers and officers in; awareness n = 337, t (335) = 4.94, p = 0.001, 2 = . 007; health benefits n = 337, t (335) = 2.92, p = 0.004, 2 = . 002 and performance purposes n = 337, t (335) = 2.48, p = 0.001, 2 = . 002. It was concluded that majority of NASE students are aware of ginger, which they mainly consumed as drinks. Further study is necessary to ascertain the size of benefits and the best way ginger use would enhance the health and job performance of military personnel.
Optimal Pressure Management in Water Distribution Systems: Efficiency Indexes for Volumetric Cost Performance, Consumption and Linear Leakage Measurements

Water is a finite resource and should be given the attention it deserves to reduce its depletion through leakages in pipe systems. The authors implemented pressure management strategies linked to fixed and variable discharge (FAVAD), the burst and background estimate (BABE), and orifice principle methodologies to analyze a two-phased comparative method for applying optimal pressure management and its efficiency indexes in measuring volumetric cost performance, consumption, leakage flowrate, linear leakage reduction, infrastructural leakage and leakage cost indices. Using time-modulated smart control pressure reducing valve (PRV) simulation processes, the authors selected Alexandra Township in Johannesburg, South Africa as a case study. The results showed a reduction in head pressure, a reduction in the system input volume (SIV) from 26,272,579 m3 to 21,915,943 m3 and a reduction in minimum night flow (MNF) from 14.01% to 12.50%. The annual estimated nodal system output (NSO) was reduced from 14,774.62 m3 to 12,787.85 m3. The monthly average linear system repairs were reduced from 246 to 177, while the efficiency index percentages of leakage frequency/km/pressure were reduced from 8.31% to 5.98%. At a unit cost of $3.18/m3, the cost of leakages declined from $4,009,315.54 to $2,862,053.10 per month, while average household consumption (AMC) reduced from 36.33 m3 to 24.56 m3. Finally, the linear reduction value R2 for the percentage of the total leakage flowrate (TLFR)/SIV declined from 0.58 to 0.5, whereas the infrastructure leakage ratio (ILI) increased from 4 to 4.3. The results fully demonstrated that optimal pressure management is an alternative way to simulate, estimate, quantify and understand where and how water is lost in a distribution system. The authors propose that the implementation of proactive leakage management and domestic background leakage repair could further assist in reducing the frequency and cost of water leakages.
Invasive Physiotherapy as a Treatment of Spasticity: A Systematic Review

Introduction Nowadays, a set of novel physiotherapy techniques have emerged, in which the physical agent used to try to reduce spasticity is applied percutaneously, specifically, through the patient’s skin. The aim of this work is to encompass all the invasive techniques used in spasticity in a single article, updating the existing bibliography. Methodology A systematic review was carried out between December 2020 and April 2021 in the Web of Science, Scopus and PubMed databases, selecting the clinical trials that used acupuncture, electroacupuncture or dry needling as a treatment for spasticity. Sixteen clinical trials were included, summarizing all the study characteristics and the outcome measures, at last the evidence was described for their results. Results Most of the studies find a difference of significant decrease in spasticity between the subjects of the experimental groups. Only four studies found no significant changes in spasticity. All the studies are carried out together with the conventional physiotherapy treatment in spasticity. Conclusion Treatment with invasive physiotherapy, combined with conventional physiotherapy, seems to have positive effects in reducing spasticity, although more studies are needed to improve the heterogeneity of the interventions and to assess their long-term effectiveness.
Prenatal Exposure to an EDC Mixture, NeuroMix: Effects on Brain, Behavior, and Stress Responsiveness in Rats

Humans and wildlife are exposed to endocrine-disrupting chemicals (EDCs) throughout their lives. Environmental EDCs are implicated in a range of diseases/disorders with developmental origins, including neurodevelopment and behavior. EDCs are most often studied one by one; here, we assessed outcomes induced by a mixture designed to represent the real-world situation of multiple simultaneous exposures. The choice of EDCs, which we refer to as “NeuroMix,” was informed by evidence for neurobiological effects in single-compound studies and included bisphenols, phthalates, vinclozolin, and perfluorinated, polybrominated, and polychlorinated compounds. Pregnant Sprague Dawley rats were fed the NeuroMix or vehicle, and then offspring of both sexes were assessed for effects on postnatal development and behaviors and gene expression in the brain in adulthood. In order to determine whether early-life EDCs predisposed to subsequent vulnerability to postnatal life challenges, a subset of rats were also given a stress challenge in adolescence. Prenatal NeuroMix exposure decreased body weight and delayed puberty in males but not females. In adulthood, NeuroMix caused changes in anxiety-like, social, and mate preference behaviors only in females. Effects of stress were predominantly observed in males. Several interactions of NeuroMix and stress were found, especially for the mate preference behavior and gene expression in the brain. These findings provide novel insights into how two realistic environmental challenges lead to developmental and neurobehavioral deficits, both alone and in combination, in a sex-specific manner.
Children’s and young people’s human rights education in school: Cardinal complications and a middle ground

Abstract This article examines the academic discussion about human rights education for children and young people and argues that the current state of research does not provide sufficient support and guidance to nations, schools, and teachers in the establishment of human rights education in schools. The article’s aim is to add insights into how scholarly work may be contributing to the low uptake of human rights education in formal schooling. By drawing on educational children’s rights research and research on human rights education, three cardinal complications are identified; (1) that the main research fields that address education and rights do not seem to communicate, (2) that it is unclear what are the aims of human rights education are, and (3) that a curriculum for human rights education is missing. The cardinal complications are closely examined and discussed, and a middle ground is explored and progressively visualized.
Long-Acting Thioredoxin Ameliorates Doxorubicin-Induced Cardiomyopathy via Its Anti-Oxidative and Anti-Inflammatory Action

Although the number of patients with heart failure is increasing, a sufficient treatment agent has not been established. Oxidative stress and inflammation play important roles in the development of myocardial remodeling. When thioredoxin (Trx), an endogenous anti-oxidative and inflammatory modulator with a molecular weight of 12 kDa, is exogenously administered, it disappears rapidly from the blood circulation. In this study, we prepared a long-acting Trx, by fusing human Trx (HSA-Trx) with human serum albumin (HSA) and evaluated its efficacy in treating drug-induced heart failure. Drug-induced cardiomyopathy was created by intraperitoneally administering doxorubicin (Dox) to mice three times per week. A decrease in heart weight, increased myocardial fibrosis and markers for myocardial damage that were observed in the Dox group were suppressed by HSA-Trx administration. HSA-Trx also suppressed the expression of atrogin-1 and myostatin, myocardial atrophy factors in addition to suppressing oxidative stress and inflammation. In the Dox group, a decreased expression of endogenous Trx in cardiac tissue and an increased expression of macrophage migration inhibitory factor were observed, but these changes were restored to normal levels by HSA-Trx administration. These findings suggest that HSA-Trx improves the pathological condition associated with Dox-induced cardiomyopathy by its anti-oxidative/anti-inflammatory and myocardial atrophy inhibitory action.
Improvement of refrigerating machine energy efficiency through radiative removal of condensation heat

In regions with a continental climate, refrigerators with air-cooled condensers operate at high condensation pressures during the summer season which reduces their efficiency and accelerates the wear of compressors. To reduce condensation pressure, it was proposed to use radiative cooling which is a way of heat removal through the planet's atmosphere to outer space in a form of infrared radiation. A refrigerating machine with an assembly of condensation heat removal including air and liquid cooling condensers connected in series has been developed. To reduce the condensation temperature, a pre-cooled heat-transfer agent is fed to the liquid cooling condenser during the day hours at high atmospheric temperatures. At night, the heat-transfer agent is cooled by radiative cooling. An experimental study of the operation of a 600 W refrigerating machine including a sealed piston compressor was conducted. R134a refrigerant was used. Supply of pre-cooled heat-transfer agent at +33.1 °С has provided a reduction of condensation temperature from +47.0 to +39.1 °С. The study was conducted at an atmospheric air temperature of +38.0 °С. The degree of pressure growth was decreased by 30 %. The refrigeration coefficient was increased by 11 %. In comparison with the conventional scheme with an air-cooled condenser, energy consumption by the system did not change in the daytime. The offered scheme of condensation heat removal reduces the pressure of condensation and provides stability for refrigerating machine operation. It can be used in stationary refrigerating machines at high daytime temperatures.
REPRODUCTIVE, SERUM BIOCHEMICAL AND HORMONAL TRAITS OF LOCAL QUAIL IN RESPONSE TO DIETARY SUPPLEMENTATION OF GREEN TEA POWDER

This study was conducted on 90 local quail females in six different treatments in order to know the effect of adding green tea powder to the quail diet on the productive, reproductive, biochemical and hormonal characteristics of quail females. The results showed a significant superiority of the birds of the group fed on 1% of green tea powder in hot and cold carcass weight, average egg weight, albumin weight, yolk height and color, and the lowest feed consumption, while the control-treated birds in the number of eggs produced, HDP, ALT, Alkaline and Bilirubin exceeded the other treatments birds. Concerning the lipid profile, blood urea ratio, and AST, the highest significant figures were recorded in the treatment of birds fed a ration to which 3% lipids were added. In contrast, the lowest values ​​for total cholesterol, Tri, VLDL, and blood nitrogen were recorded for birds of the treatment fed at 2% of green tea powder. The results showed that there were significant differences between the six treatment birds in the level of blood hormones, as the highest level of (estrogen), (Ghrelin, leptin, FSH), (T4) and (Growth and LH) were recorded for the control birds, 3% lipid and 1% dried green tea and 2% green tea with 3% lipid, respectively. We conclude from the above that birds fed a supplemented diet of 1% green tea powder were superior in most productive and reproductive traits, especially carcass weight, dressed %, egg weight and internal egg characteristics, compared to other treated birds.