Miracle-dz/UniFAR-FTUs huggingface dataset:
Enhancing Thai elementary students’ English and maintaining Thainess using localized materials: Two putative confronting forces

In Thailand, concerns over the imperative need to improve its citizens’ English proficiency and the unsatisfactory English learning outcomes have long been present. In addition, ongoing globalization has raised another concern that Thainess is being eroded due to external influences. This study attempted to compromise these two seemingly conflicting forces by enhancing Thai students’ global English and maintaining local Thainess associated with three regions of Thailand. First, a set of instructional innovations for elementary English education was constructed in each region. These were based on prominent characteristics of local Thainess elicited through a questionnaire completed by local community members and subsequently implemented in Grade 4 classes at three schools in each region of Thailand for ten weeks. Next, two separate sets of pretests-posttests corresponding to each instructional set were constructed and administered to assess their local Thainess and English knowledge. Finally, to ensure that the knowledge gained from the instruction was put into practical use, a tour guide simulation task was conducted by the students. The analysis of the test scores demonstrates that localized lessons were beneficial, enhancing their local Thainess knowledge and associated English vocabulary. The accomplishment of the task thus represented their knowledge of local Thainess and English, contributing to a sense of pride in their nation and a sense of achievement in their English proficiency and instruction.
Assessment of the Effects of SARS-Cov-2 Infection on Multiple Organs Using Laboratory Indices

Background: Severe acute respiratory syndrome coronavirus 2 (SARS-Cov-2) is still a severe threaft for human health currently, and the researches about it is a focus topic worldwide. Aim of the study: In this study, we will collect some laboratory results of the patients with coronavirus disease (COVID-19) to assess the function of liver, heart, kidney and even pancreas. Subjects and Methods: Laboratory results of the patients with COVID-19 are collected. The biochemical indices are classified and used to assess the according function of liver, heart, kidney; meantime, and blood glucose is also observed and taken as an index to roughly evaluate pancreas. Results: There were some indices exhibited abnormal. For patient 1, the ratio of albumin and globulin slightly was lower than the down-limit of reference range. For patient 2, alanine aminotransferase (ALT), aspartate aminotransferase (AST), gamma-glutamyltransferase (GGT), creatine kinase (CK), creatinine kinase-MB isoenzyme (CK-MB), lactate dehydrogenase (LDH), alpha-hydroxybutyric dehydrogenase (HBDH), and beta-2 microglobulin (β2-MG) were respectively higher than the according upper limit of the reference range, while prealbumin (PA) was lower than the down limit. For patient 3, GGT, CK, PA were high than normal range. For patient 4, CK, LDH, HBDH were higher than the upper range. Conclusion: Infection of SARS-Cov-2 could cause liver and heart injury, and it is suggested that clinicians and researchers should pay more attention on the prevention, treatment and causative mechanism of such an injury.
CMAR_A_321428 7165..7174

1Key Laboratory for Experimental Teratology of the Ministry of Education and Department of Pathology, School of Basic Medical Science, Cheeloo College of Medicine, Shandong University, Jinan, Shandong Province, 250012, People's Republic of China; 2Department of Medical Oncology, Qilu Hospital (Qingdao), Cheeloo College of Medicine, Shandong University, Qingdao, 266035, Shandong Province, People’s Republic of China; 3Department of Medical Oncology, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, 250012, Shandong Province, People’s Republic of China; 4Department of Radiation Oncology, Heze Municipal Hospital, Heze, 274031, Shandong Province, People’s Republic of China; 5Department of Respiratory Disease, Zhejiang Provincial People’s Hospital, Hangzhou, 310000, Zhejiang Province, People’s Republic of China
Temperature and concentration polarization in membrane distillation: a technical review

Recently, the seawater and brackish water desalination process have gained widespread attention due to the scarcity of drinking water. Among several membrane distillation (MD) methods for desalination, vacuum membrane distillation (VMD), and direct contact membrane distillation (DCMD) are mostly focused techniques. However, there are several technical issues associated with these techniques that have a negative impact on their performance. The most influential of them are temperature polarization (TP) and concentration polarization (CP) that reduces the permeate flux significantly. A state-of-the-art review is presented to gain a clear understanding of, the impact of both the TP and CP on various performance parameters and methods to overcome these obstacles. The main focus is on the causes of TP and CP, theoretical models, experimental key findings for TP and CP, and their impact on the performance of VMD and DCMD. For DCMD, the value of TPC for channels with spacers falls in the range of 0.9–0.97, whereas for flow channels without spacers, the TPC was in the range of 0.57–0.76. Finally, different methods are discussed to overcome the TP and CP.
PPA_A_285768 2051..2061

1Division of Medical Senology, IEO European Institute of Oncology IRCCS, Milan, Italy; 2Division of Early Drug Development for Innovative Therapies, IEO European Institute of Oncology IRCCS, Milan, Italy; 3Department of Oncology and Hemato-Oncology, University of Milan, Milan, Italy; 4Applied Research Division for Cognitive and Psychological Science, IEO European Institute of Oncology IRCCS, Milan, 20141, Italy Abstract: Adjuvant endocrine therapy (AET) is generally proposed to all patients with hormone receptor-positive breast cancer to reduce the risk of recurrence and death. Adherence to therapy is crucial. However, non-adherence to AET is common, with estimates of up to 50% of patients not successfully completing a five-year course of treatment, and it is significantly associated with lower survival rates and a higher risk of recurrence. Currently, no gold standard is available to assess adherence. Several studies, most of them retrospective in nature, have used both direct and indirect methods to monitor the adherence to therapy in breast cancer. The indirect method is more widely used, and it is based on pharmacy prescription refills and patient administered questionnaires. On the other hand, direct methods such as a measurement of the level of the drug or its metabolites in blood or urine are much more precise, but more expensive and not routinely implemented. In this review, we analyzed the results of the major studies focused on the adherence to tamoxifen in breast cancer patients. We identified several factors associated with poor adherence, such as the side effects of therapy, the lack of shared decision-making between the physician and patient, the context in which the discussion takes place, and whether the patients are enrolled in a clinical trial. Moreover, we discussed possible methods to improve adherence to adjuvant therapy in breast cancer.
Bacillus-based products for management of kiwifruit bacterial canker

Pseudomonas syringae pv. actinidiae is an important pathogen of kiwifruit (Actinidia deliciosa), and bacterial canker of this host is managed by monitoring and chemical control strategies. The efficacy of the bio-pesticides Amylo-X® (based on Bacillus amyloliquefaciens subsp. plantarum strain D747) and Serenade Max® (strain QST713 of B. subtilis) was evaluated by in vitro and in vivo experiments. Both antagonists inhibited different biovars of the pathogen in in vitro assays; QST713 was more efficient than D747. The two Bacillus strains also colonized A. deliciosa flowers (c. 105-7 cfu per flower) up to 96 h after inoculation. D747 persisted on leaves (c. 104-6 cfu cm-2) up to 4 weeks after inoculation, during 2 years in Emilia Romagna and Latium regions of Italy. On flowers, the antagonists reduced pathogen populations, compared to untreated (control) flowers. On A. deliciosa and A. chinensis plants under controlled conditions, Amylo-X® reduced severity of bacterial canker, providing ca. 50% relative protection on A. deliciosa and 70% on A. chinensis. Serenade Max® was less effective, giving 0% relative protection on A. deliciosa and 40% on A. chinensis. In a field trial, on A. deliciosa plants, Amylo-X® reduced the severity of bacterial canker on leaves, providing ca. 40% relative protection. The sensitivity of both antagonistic strains to streptomycin sulphate was confirmed by testing the most used concentration where antibiotics are approved for management of bacterial pathogens.
Diversity of longhorned beetles (Coleoptera: Cerambycidae) in the Caribbean region of Colombia: temporal variation between two fragments of tropical dry forest

Abstract: The tropical dry forest is under constant threat from many anthropic activities which are conducted indiscriminately, modifying the forest, and therefore, affecting species that are closely related to its phenology, such as longhorned beetles (Cerambycidae). The spatio-temporal variation of the cerambycid diversity in two fragments of tropical dry forest (Reserva Campesina la Montaña and La Flecha) in the Caribbean region of Colombia was analyzed. At each locality, four squared plots were delimited, and the beetles were collected with fruit traps, beating sheets and manual capture, and with light traps in the center. Five hundred eighty-seven specimens representing 128 species were collected, of which members of the tribe Ectenessini (Cerambycinae) were the most abundant. At the subfamily level, Cerambycinae was the most abundant (465 specimens) and diverse (73 species), followed by Lamiinae and Prioninae. The highest values of richness (110 species), abundance (428), biomass (21.18 g), and as well as the highest values of true diversity (1D= 73.44, 2D= 34.30) were found during the first precipitations. Regarding beta diversity, temporal variation was determined and mainly explained by a high percentage of turnover (> 70%). Lastly, the high diversity of Cerambycidae was associated with high values of relative humidity and canopy cover during the rainy season. This showed that the structure of the cerambycid community in the tropical dry forest of the Caribbean region of Colombia depends on these variables, which are closely related to precipitation.
RMHP_A_313368 3783..3795

1Department of Health Information Management & Technology; College of Public Health; Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia; 2Risk Management and Patient Safety Department; Dammam Medical Complex, Dammam, Saudi Arabia; 3Risk Management Unit, Directorate of Quality and Safety, King Fahad Hospital of the University, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia Purpose: The objective of the present study is to explore the perceptions of patient safety culture (PSC) among King Fahd University Hospital’s (KFUH) employees and to develop recommendations to overcome the factors that impede the integration of PSC in the study setting. Methods: This is a cross-sectional study that assessed the level of PSC at KFUH. This study used the Hospital Survey on Patient Safety Culture tool from all KFUH healthcare workers (n=900) in 2018. Findings: The response rate of the study was 67%. Findings show that KFUH excelled in three PSC composites: continuous organizational learning, feedback and communication about error, and frequency of events reported. In contrast, staffing, teamwork within units, and non-punitive response to error yielded low composite scores. Originality/Value: The strength of the present study was the use of a valid questionnaire that has been used widely in the literature with a large sample size, which yielded valid results. It is, to our knowledge, the first research study that analyzes health workers’ perceptions on patient safety culture in a teaching hospital in Eastern Province in KSA and compares it with Agency for Healthcare Research and Quality (AHRQ) and Saudi Hospital Survey on Patient Safety Culture (HSPSC). Results from the study highlight the need to employ an adequate number of workers, implement continuous patient safety training programs, and adopt safety programs and policies.
NDT_A_332967 2937..2954

*These authors contributed equally to this work Background: The obstacle of limb motor caused by stroke, especially the decline of motor function of upper limbs, can directly affect the activities of daily living of stroke patients with hemiplegia. Based on long-term clinical practice, the treatment effect of electrical stimulation methods for stroke limb dysfunction has been widely recognized and supported by authoritative guidelines and systematic reviews. However, which electrical stimulation method is the optimum in the treatment of stroke limb dysfunction is still a controversial issue. Objective: In this paper, we adopted Network Meta-Analysis (NMA) to rank the priorities of various electrical stimulation methods, so as to select the optimal electrical stimulation method and discuss its rationality in guiding clinical practice. Methods: We carried out a systematic review by searching a total of 6806 studies from 8 databases and 2 clinical trial registries, and finally screened out 34 studies for further investigation. Then, pairwise meta-analysis and Bayesian network meta-analysis were employed to evaluate the effectiveness and ranking of various interventions. The primary outcome measure was Fugl-Meyer Assessment Upper Extremity (FMA-UE), and the secondary outcome measures were Modified Barthel Index (MBI) and Modified Ashworth Scale (MAS). Finally, the risk of bias, publication bias and sensitivity of the Randomized Controlled Trials (RCTs) were evaluated. Results: On the basis of comprehensive rehabilitation treatment (RT), the Functional Electrical Stimulation (FES) was superior than other electrical stimulation methods in improving both FMA-UE and MBI. Meanwhile, the results indicated that the Transcutaneous Electrical Acupoint Stimulation (TEAS) was the only electrical stimulation method that showed treatment advantages in reducing MAS. Conclusion: The study showed that FES had the optimal overall rehabilitation effect on upper limb dysfunction of stroke patients based on the comprehensive RT, while the treatment effect of TEAS on upper limb spasticity after stroke was the most significant.
The relationship between bone mineral indices and survival in patients on peritoneal dialysis

Introduction: Disorders of minerals metabolism are common metabolic problems in patients undergoing peritoneal dialysis (PD) which causes increase in mortality and morbidity in these patients. Objectives: In this study, the relationship between bone metabolic indices and mortality rate in patients on PD was assessed. Patients and Methods: Data were collected from Iranian peritoneal dialysis registry database, covering the period 2009–2015 and comprised 2000 adult patients. Patients with less than three months follow-up and incomplete data were excluded. Demographic and some laboratory data (including age, gender, body mass index, serum albumin, dialysis vintage and comorbidities) of patients recorded. Additionally, the unadjusted and adjusted, hazard ratios (HRs) of serum phosphorus (P), calcium (Ca) and parathyroid hormone (PTH) levels, to find their association with mortality were calculated, using the Cox proportional-hazards model. Results: In total, 1197 out of 2000 patients had the inclusion criteria and were included in the study. We found that serum iPTH (intact parathyroid hormone) over 600 pg/mL significantly increased the mortality rate by 2.7 times compared to iPTH levels between 200 to 600 pg/ mL (HR: 2.7, P=0.002). Additionally, the serum phosphorus level less than 4 mg/dL was significantly (P=0.0001) related to higher mortality rate (HR: 1.6). There was no significant association of serum calcium and alkaline phosphatase (ALP) levels with mortality (P > 0.05). Conclusion: Although high serum iPTH and low-serum phosphorus levels could determine the mortality risk in PD patients, Ca and ALP levels were not risk factors for mortality.
Research Progress of the Clinical Application of Small Cell Lung Cancer Related Tumor Markers and Biochemical Indicators

With continual advances in medicine, more studies on early diagnosis, therapeutic evaluation, and prognosis of lung cancer have emerged in recent years, particularly in regard to small cell lung cancer (SCLC), which is a pathological type of lung cancer with the highest grade. In the era of medical treatment scarcity, early diagnosis of SCLC, evaluation of treatment effect, recurrence factors, and prognosis are important to treat patients with SCLC, prolong their survival, and improve their life quality. The research on the changes of serum tumor markers and biochemical indicators in the early diagnosis and treatment of SCLC has gradually become a hot topic. Therefore, this article reviews the research progress of serum tumor markers and biochemical indicators of SCLC.
Adversarial Sample Detection with Gaussian Mixture Conditional Generative Adversarial Networks

It is important to detect adversarial samples in the physical world that are far away from the training data distribution. Some adversarial samples can make a machine learning model generate a highly overconfident distribution in the testing stage. Thus, we proposed a mechanism for detecting adversarial samples based on semisupervised generative adversarial networks (GANs) with an encoder-decoder structure; this mechanism can be applied to any pretrained neural network without changing the network’s structure. The semisupervised GANs also give us insight into the behavior of adversarial samples and their flow through the layers of a deep neural network. In the supervised scenario, the latent feature of the semisupervised GAN and the target network’s logit information are used as the input of the external classifier support vector machine to detect the adversarial samples. In the unsupervised scenario, first, we proposed a one-class classier based on the semisupervised Gaussian mixture conditional generative adversarial network (GM-CGAN) to fit the joint feature information of the normal data, and then, we used a discriminator network to detect normal data and adversarial samples. In both supervised scenarios and unsupervised scenarios, experimental results show that our method outperforms latest methods.
VHRM_A_324112 591..600

1Private Vascular Specialist, Paris, France; 2Pedagogical Support Office, Faculty of Medicine Pitié-Salpétrière, Sorbonne University, Paris, France; 3Hospital Albert Einstein, São Paulo, Brazil; 4Laboratoire Innotech International, Arcueil, France Abstract: Flavonoids are oral venoactive drugs frequently prescribed to relieve the symptoms of chronic venous disorders (CVD). Among venoactive drugs, diosmin is a naturally occurring flavonoid glycoside that can be isolated from various plant sources; it can also be obtained after conversion of hesperidin extracted from citrus rinds. Micronized purified flavonoid fraction (MPFF) is a preparation that contains mainly diosmin and a small fraction of hesperidin. We performed a state-of-the-art literature review to collect and analyze wellconducted randomized clinical studies comparing diosmin – also called non-micronized or hemisynthetic diosmin – 600 mg a day and MPFF, 1000 mg a day. Three clinical studies met the criteria and were included for this literature review. These clinical studies showed a significant decrease of CVD symptom intensity (up to approximately 50%) and global patient satisfaction after one-to-six-month treatment with diosmin or MPFF, without statistical differences between these two forms of diosmin. Both treatments were well tolerated with few mild adverse drug reactions reported. Overall, based on this literature review, there is no clinical benefit to increase the dose of diosmin beyond 600 mg per day, to use the micronized form, or to add hesperidin, since clinical efficacy on venous symptomatology is achieved with 600 mg per day of pure non-micronized diosmin. This challenges the status of diosmin – 600 mg a day – in guidelines for the management of CVD, which is currently categorized 2C (weak recommendations for use and poor quality of evidence), while the most widely used and assessed preparation MPFF is rated 1B (strong recommendation for use and moderate quality of evidence).
First record of Scinax centralis (Anura, Hylidae) in the Triângulo Mineiro region, state of Minas Gerais, southeastern Brazil, with further data on its vocalization

Scinax comprises more than 120 species which are split in two clades, the S. ruber and the S. catharinae clades. A few species within the S. catharinae clade occur in gallery forests of the Brazilian Cerrado. We here extend the distribution of S. centralis southwards based on new populations sampled in the banks of the Rio Paranaíba, in the borders of Minas Gerais (MG) and Goiás (GO) states, southeastern Brazil. We also provide further data on the species vocalization. Variation was seen among our population and topotypes regarding SVL and call dominant frequency, both likely representing a clinal variation. Our new population of S. centralis represents the first record of the species for the state of Minas Gerais.
Deep Learning-Based Approach for Diagnosis of COVID-19 Patients from CT Lung Images

COVID-19 is currently one of the most life-threatening problems around the world. The fast and accurate detection of the COVID-19 infection plays an important role in identifying, making better decisions as well as ensuring treatment for the patients. In this study, we propose an approach to identify COVID-19 patients via deep learning methods. The proposed approach includes two steps: segmentation of lung and classification of patients via analyzing the segmented images. Especially, in the first step, the attention gate is integrated into Unet neural network structure, which can help increase the accuracy of the segmentation tasks. In the second step, the EfficientNet-B4 is applied to classify COVID-19 patients. By using EfficientNet, the performance of the classification process as well as the size of the model are improved. We apply the proposed approach for the database including 130 patients. Experimental results show the desired performances of the proposed approach.