Miracle-dz/UniFAR-FTUs huggingface dataset:
Predictors of Land-Based Activity Participation in a National Representative Sample of Indigenous Individuals Living Off-Reserve

This study examined data from the 2017 Aboriginal Peoples Survey to consider predictors of land-based activity engagement. We hypothesized that higher self-reported mental and physical health scores, an increased sense of cultural belonging, living in a rural community, and no prior individual or family history of residential school attendance would predict a higher frequency of land-based activity engagement among First Nations individuals living off-reserve. Results from linear regression analyses suggested that an increased sense of cultural belonging, being male, and living in a rural community with a population of less than 1000 people were significant predictors of the frequency of land-based activity engagement. With these preliminary findings, further research can explore how physical and mental health outcomes influence the frequency of land-based activity engagement, in addition to how community-specific indicators may promote higher frequency of these activities, particularly among First Nations individuals living off-reserve.
Development of Basic Biology Textbook Based Integration of Science and Islam

Lecturers have the opportunity to spread the values of science and Islam to biology students at PTKIN. One of the efforts is to make a basic biology book that integrates it into Islamic teachings. The aim of this study was to test the validity and practicality of the Biology book which is integrated with Islam (Alquran). In addition to the identification of Surahs and verses of the Alquran that explain basic biological material in semester 1. This research is R&D. The validity and practicality of the data were analyzed using a Likert scale. The technique of collecting data by means of FGD as many as 9 students and 4 lecturers. The results showed that the basic biology textbooks based on the integration of science and Islam at IAIN Kudus were declared valid with very good criteria and practical with very good criteria. The content of this book consists of 12 chapters, namely biology as a science, cells and viruses, tissue structure of animals and plants, biological diversity, metabolism, nervous and endocrine systems, digestive systems, reproductive systems, circulatory systems, principles of genetics, evolution, and biotechnology. The material was then inserted verses scattered in the Alquran.
Radiographic and clinical assessments of platform switching implant assisted mandibular overdenture in controlled diabetic patients

bone level changes where the peri-implant bone loss in the first year [5] . The switching has enhanced the development of biologic width. The ABSTRACT Background: Currently platform switching concept is widely used in implant dentistry; however, its influence on the health of surrounding soft tissue and marginal bone level alterations in implant assisted overdentures and especially in controlled diabetic patients, remains inconclusive. Objective: The purpose of this research was to assess the viability of platform-switched implants for improvement of osseous and soft tissue response in implant-assisted mandibular overdentures in completely edentulous controlled diabetic patients having type 2 diabetes mellitus (T2DM) and compare it with non diabetic patients as control group. Material and method: Fourteen completely edentulous patients were included in this study, two groups were formed; Group I patients who are non diabetic (as control group) and group II patients medically diagnosed T2DM and controlled. New upper and lower complete dentures were constructed following the conventional steps. For all participants, two platform-switching implants were inserted in the mandibular canine area following flapless technique guided by 3D printed surgical guide constructed according to the planned CBCT data evaluation. Immediate loading protocol was applied as pick up of the metal housing of the attachment was done in the day of implant placement. Gingival index and pocket depth were measured at one week after implant placement, 3, 6 and 12 months follow-up. While peri-implant marginal bone level was measured at loading time, 6 and 12 months follow-up. For diabetic patients (group II) hemoglobin A1c test was done every three month for monitoring their medical condition. Data collected were statistically analyzed. Results: Peri-implant bone loss of higher values was found in diabetic patients (group II) compared to non diabetic patients (group I) but with no statistical significance along the study period follow up records. Peri-implant gingival index and pocket depth showed no statistical significance along the study period with better value for non diabetic patients compared to diabetic patients. Conclusions: Within the limitations of this study, it was revealed that using two platform switching implants in assisting mandibular overdenture is a successful and predictable treatment option for type2 controlled diabetic patients as non diabetic patients. Peri-implant bone loss was found in type2 controlled diabetic patients higher but insignificantly when compared to non diabetic patients during one year follow up period. Regarding the clinical assessment there was no significant difference in both groups with consideration of continuous glycemic control and optimum oral hygiene measures.
Turistlerin Artırılmış Gerçekliğe Dayalı Tur Rehberi Uygulamalarını Kabul Etme Eğilimlerinin İncelenmesi Üzerine Bir Araştırma (A Study on the Investigation of Tourists Tendency to Adopt Augmented Reality-Based Tour Guide Applications)

Tur rehberliği hizmetlerinde artırılmış gerçeklik-temelli rehberlik uygulamalarına yönelik araştırmaların turizm yazınında sınırlı bir kapsamı teşkil ettiği görülmektedir. Buradan hareketle araştırmada, tur rehberi uygulamalarının benimsenmesinde rol oynayan unsurların irdelenmesi, faydalı bilgileri ortaya çıkaracaktır. Bu nedenle, turistlerin artırılmış gerçekliğe dayalı tur rehberi uygulamalarını benimseme niyetleri Değer Temelli Benimseme Teorisi (DTB) çerçevesinde incelenmiştir. Araştırmada nicel araştırma yöntemi benimsenmiş olup, veriler anket tekniği ile toplanmıştır. Bu kapsamda son 12 ay içinde tatil deneyimi gerçekleştirmiş olan 291 turistin örneklem olarak alındığı araştırma modeline has hipotezler, PLS-SEM aracılığıyla analiz edilmiştir. Araştırma sonucunda, artırılmış gerçekliğe dayalı tur rehberi uygulamalarına yönelik algılanan değer (AD)’in, algılanan kullanışlılık (AK), algılanan haz (AH), algılanan teknik özellik (AT) ve algılanan finansal bedel (AF) değişkenlerinin tamamı tarafından pozitif yönde ve anlamlı olarak açıklandığı görülmüştür. Benzer şekilde, algılanan değer değişkeninin, artırılmış gerçekliğe dayalı tur rehberi uygulamalarına yönelik benimseme niyetini (DN) pozitif yönde ve anlamlı olarak açıkladığı görülmüştür. Araştırma kapsamında elde edilen sonuçlar teorik ve pratik açıdan tartışılmıştır.
Predicting Current and Future Potential Distributions of Parthenium hysterophorus in Bangladesh Using Maximum Entropy Ecological Niche Modelling

Parthenium weed (Parthenium hysterophorus L.) is among the most noxious invasive alien plant species, which can pose a threat to agro- and native-ecosystems. Despite potential parthenium infestation risks at the south-western regions of the Ganges–Brahmaputra floodplains of Bangladesh, no studies exist that document parthenium infestation. Using field surveys and a maximum entropy (Maxent) modelling approach, the present study tries to address the problem in the concerned region comprised of five Districts: Jashore, Jhenaidah, Chuadanga, Meherpur, and Khustia. The results revealed high infestation in the Jashore, Jhenaidah, and Chuadanga Districts, mainly along roadsides, in grasslands, and in fallow and cropped fields. The greatest abundance of the weed (ca. 30 plants m−2) occurred at the Indian border area, suggesting cross-border spreading, possibly through the linking road systems. Furthermore, we found that under both low and high emissions scenarios (Representative Concentration Pathways 2.6 and 8.5), parthenium weed suitability areas were likely to expand, suggesting an increased threat to the agro-ecosystems of Bangladesh. The present study is the first attempt to survey and model potential parthenium weed distribution affecting one of the major hubs of agricultural production in Bangladesh. The findings of this study can help land managers to make judicious decisions towards the future management of these agro-ecosystems.
An Investigation on the Impact of Training and Development on Service Quality in the Higher Education Sector

The most powerful competitive trend that is currently shaping marketing and business strategies is service quality. Therefore, this study delves into the effect of training and development of employees on service quality in the context higher education. Emphasis is placed on the relationship between the perception of employees with regards to training and development, and the perception of customers with regards to the service provided by specific employees. A self-administered questionnaire was distributed to 296 employees and 1480 students in Aden University in Yemen. The findings, attained through confirmatory factor analysis and structural equation modelling, revealed a positive relationship between training and development and service quality. This positive relationship was observed to be particularly obvious for the more highly qualified employees. This study conclude that, when employees provided by training and development, they will put greater effort into the delivery of good service quality, thus promoting a positive perception among customers towards the organization. A discussion on the limitations of this investigation, and suggestions for future research was included.
11β-Hydroxysteroid Dehydrogenase Type 1 within Osteoclasts Mediates the Bone Protective Properties of Therapeutic Corticosteroids in Chronic Inflammation

Therapeutic glucocorticoids (GCs) are powerful anti-inflammatory tools in the management of chronic inflammatory diseases such as rheumatoid arthritis (RA). However, their actions on bone in this context are complex. The enzyme 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) is a mediator of the anti-inflammatory actions of therapeutic glucocorticoids (GCs) in vivo. In this study we delineate the role of 11β-HSD1 in the effects of GC on bone during inflammatory polyarthritis. Its function was assessed in bone biopsies from patients with RA and osteoarthritis, and in primary osteoblasts and osteoclasts. Bone metabolism was assessed in the TNF-tg model of polyarthritis treated with oral GC (corticosterone), in animals with global (TNF-tg11βKO), mesenchymal (including osteoblast) (TNF-tg11βflx/tw2cre) and myeloid (including osteoclast) (TNF-tg11βflx/LysMcre) deletion. Bone parameters were assessed by micro-CT, static histomorphometry and serum metabolism markers. We observed a marked increase in 11β-HSD1 activity in bone in RA relative to osteoarthritis bone, whilst the pro-inflammatory cytokine TNFα upregulated 11β-HSD1 within osteoblasts and osteoclasts. In osteoclasts, 11β-HSD1 mediated the suppression of bone resorption by GCs. Whilst corticosterone prevented the inflammatory loss of trabecular bone in TNF-tg animals, counterparts with global deletion of 11β-HSD1 were resistant to these protective actions, characterised by increased osteoclastic bone resorption. Targeted deletion of 11β-HSD1 within osteoclasts and myeloid derived cells partially reproduced the GC resistant phenotype. These data reveal the critical role of 11β-HSD1 within bone and osteoclasts in mediating the suppression of inflammatory bone loss in response to therapeutic GCs in chronic inflammatory disease.
New surgical model to induce irreversible liver fibrosis by surgical closure of major duodenal orifice in dogs

This study was conducted to induce and evaluate irreversible hepatic fibrosis in dogs by surgical closure of the major duodenal orifice. The study was performed on six healthy local adult dogs. Irreversible hepatic fibrosis was surgically induced in all animals by surgical closure of major duodenal papilla using non-absorbable suture material for 60 days. Induced hepatic fibrosis was evaluated by clinical, ultrasonographical examination, laboratory and histopathological methods. The clinical manifestation of the jaundiced dogs showed reduced food intake, pale-yellowish mucus membrane, inflammatory signs of wound site and severe post-operative pain. Biochemically, there was significant increased values of the aspartate aminotransferase, alkaline phosphatase, alanine aminotransferase, indirect bilirubin, direct bilirubin and total bilirubin especially during first two days after surgery followed by a gradual decrease of these values until the end of the but still higher than normal values. Ultrasonographic examinations showed abnormal change in the liver tissue such as increase in both size and wall thickness of the gall bladder and mottled heterogeneous appearance of the liver during the first two weeks following the surgical induction of the hepatic fibrosis and lasted until the end of the study. Histopathological evaluation of liver samples revealed necrosis of hepatocytes and deposition of eosinophilic material, infiltration of inflammatory cells, recent thrombus in the hepatic vein, fatty change. In conclusion, surgical induction of irreversible hepatic fibrosis in dogs was feasible technique by surgical closure of major duodenal papilla and the results were confirmed by the clinical, ultrasonographical, laboratory and histopathological examination.
Profile of Amino Acids Production from Microalgae Nannochloropsis sp. Biomass using Subcritical Water Technology

The amino acids from microalgae could be used as a substitute for food and feed supplements in the future. This study investigates the production of amino acids from microalgae Nannochloropsis sp. biomass using subcritical water technology approaches. The yield and composition of amino acids produced from subcritical water of microalgae Nannochloropsis sp. were evaluated at different temperatures (160-350 °C), time (3-30 min), and biomass loadings (1- 15% w/v). Overall results showed that the highest yield of total amino acids (1531.98 mg/100 g algae) was obtained at subcritical water operating conditions of 280 °C, 15 min reaction time, and 1% biomass loading. The studied operating conditions produced a higher yield of non-essential amino acids compared to essential amino acids. The study demonstrated that each of the individual amino acids investigated produced the highest at different ranges of subcritical water conditions. Thus, the obtained profile of the individual amino acid showed that careful management of operating parameters (temperature, time, and biomass loading) is crucial for identifying the amino acids of interest via subcritical water technology.
Antibiotic Resistance Genes Associated with Marine Surface Sediments: A Baseline from the Shores of Kuwait

Marine sediments are a sink for antibiotic resistance genes (ARGs) and antibiotic-resistant microbes (ARMs). Wastewater discharge into the aquatic environment is the dominant pathway for pharmaceuticals reaching aquatic organisms. Hence, the characterization of ARGs is a priority research area. This baseline study reports the presence of ARGs in 12 coastal sediment samples covering the urban coastline of Kuwait through whole-genome metagenomic sequencing. The presence of 402 antibiotic resistance genes (ARGs) were recorded in these samples; the most prevalent were patA, adeF, ErmE, ErmF, TaeA, tetX, mphD, bcrC, srmB, mtrD, baeS, Erm30, vanTE, VIM-7, AcrF, ANT4-1a, tet33, adeB, efmA, and rpsL, which showed resistance against 34 drug classes. Maximum resistance was detected against the beta-lactams (cephalosporins and penam), and 46% of genes originated from the phylum Proteobacteria. Low abundances of ESKAPEE pathogens (Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumonia, Acinetobacter baumanii, Pseudomonas aeruginosa, Enterobacter sps., and Escherichia coli) were also recorded. Approximately 42% of ARGs exhibited multiple drug resistance. All the ARGs exhibited spatial variations. The major mode of action was antibiotic efflux, followed by antibiotic inactivation, antibiotic target alteration, antibiotic target protection, and antibiotic target replacement. Our findings supported the occurrence of ARGs in coastal marine sediments and the possibility of their dissemination to surrounding ecosystems.
Polyethylenimine as a gene delivery tool in triple-negative breast cancer cell line and breast cancer stem cell model

Background and purpose: PEI is a cationic polymer able to neutralise negative DNA charges and to condense large genes which makes it suitable for gene delivery in human cells. Despite its low cost, simplicity of use and moderate toxicity, there is still room for broader usage and experimental adjustments, especially in cell lines that are difficult to transfect. In the presented research, we used PEI for the delivery of plasmid DNA into TNBC cell line SUM159 and breast CSC model HMLE-Twist.Material and methods: Cultured cells were transfected with GFP-expressing plasmid using both PEI and Lipofectamin. Transfection efficiency was determined by flow cytometry measurements of the intensity of the green fluorescence, while viability was determined by measuring intensity of the red fluorescence after propidium iodide staining. Results: In SUM159 and HMLE-Twist cells we obtain transfection efficiency between 30-40% using PEI, while cytotoxicity was generally low to moderate. PEI caused 10% of cell death in SUM159 and 20 % in HMLE-Twist. Transfection efficiency of PEI was comparable and even higher than the efficiency of the Lipofectamine in both SUM159 and HMLE-Twist. In mammary epithelia (control HMLE) we obtained only 20 % transfection efficiency using both carriers.Conclusions: We demonstrated for the first time that PEI represents a suitable nanocarrier for gene delivery into breast CSC model. We successfully transfected both breast CSC model HMLE-Twist and TNBC line SUM159. Since PEI is inexpensive and easy to use, we recommend it for further exploitations of these cell lines in TNBC research.
Luxury Brand Perception, Social Influence, and Brand Personality to Predict Purchase Intention

The key purpose of this study is to investigate the relationships between luxury brand perception, social influence, and brand personality towards purchase intention. It has been increasingly important for every company to improve its customers’ purchase intention in order to maintain the existence of the company, especially in an increasingly competitive business environment. Hence, this study was conducted to examine whether luxury brand perception, social influence, and brand personality have a positive and significant impact on purchase intention. This study was descriptive research and was conducted by using the cross-sectional method. The population of this research was all Indonesian smartphone users, and the sampling frame was limited to smartphone users who live in Jakarta, whereas purposive sampling was conducted for the data collection from respondents. The data collection was conducted by distributing questionnaires to 100 respondents through the internet and this study used SmartPLS software version 3.2. 7. for the data analysis. The result of this study showed that luxury brand perception, social influence and brand personality have a significant and positive impact towards purchase intention. Therefore, it is essential for smartphone companies to maintain their image as a luxury brand, observe and improve customers’ influence to the others about the brand, and also associate the brand’s personalities with customers in order to increase the customers’ purchase intention. Niat pembelian memiliki peran yang semakin penting untuk setiap perusahaan karena pada saat ini, menghasilkan penjualan bukan hanya bertujuan untuk memperoleh keuntungan, tetapi juga untuk mempertahankan keberadaan perusahaan, khususnya dari kondisi persaingan yang semakin meningkat. Tujuan utama penelitian ini adalah untuk meneliti hubungan yang terjadi diantara persepsi terhadap luxury brand, pengaruh sosial dan brand personality terhadap niat pembelian. Penelitian ini merupakan penelitian deskriptif dan dilakukan dengan menggunakan metode cross-sectional. Populasi pada penelitian ini adalah seluruh pengguna smartphone di Indonesia dan sample pada penelitian ini dibatasi pada pengguna smartphone yang berdomisili di Jakarta, dimana purposive sampling digunakan untuk mengumpulkan data dari responden. Pengumpulan data dilakukan dengan mendistribusikan kuesioner kepada 100 oorang responden melalui internet dan penelitian ini menggunakan perangkat lunak SmartPLS versi 3.2. 7. untuk melakukan analisis data. Hasil penelitian ini menunjukkan bahwa persepsi terhadap luxury brand, pengaruh sosial dan brand personality memiliki pengaruh yang positif dan signifikan terhadap niat pembelian. Oleh sebab itu, merupakan sebuah hal yang penting bagi perusahaan smartphone untuk mengembangkan persepsi terhadap luxury brand, pengaruh sosial dan brand personality pelanggan untuk meningkatkan niat pembelian pelanggan.
Increased Secondary Attack Rates among the Household Contacts of Patients with the Omicron Variant of the Coronavirus Disease 2019 in Japan

This study investigated the household secondary attack rate (HSAR) of patients with coronavirus disease (COVID-19) during the omicron variant-dominant period. The HSAR of COVID-19 cases during the omicron variant-dominant period (4–20 January 2022) was calculated and compared with the delta variant-dominant period (20 August to 7 November 2021) in Itako, Japan. In Itako, all 47 and 119 samples tested during the omicron and delta variant-dominant periods were negative and positive, respectively, for the L452R mutation. We used a generalized estimating equation regression model. The HSAR was 31.8% (95% confidence interval (CI) 27.7–36.2) for 456 household contacts during the omicron variant-dominant period; it was higher than that during the delta variant-dominant period (25.2%) (adjusted risk ratio [aRR] 1.61, CI 1.13–2.28). During the omicron variant-dominant period, HSAR was lower for the household contacts of completely vaccinated index patients (27.3%) than for contacts of other index patients (41.2%) (vaccine effectiveness for infectee 0.43, 95% CI 0.16–0.62) and was significantly higher for female contacts than for male contacts (36.2% vs. 26.1%; aRR 1.29, 95% CI 1.01–1.65). The HSAR was significantly higher during the omicron variant-dominant period than the delta variant-dominant period. The vaccination of index patients might protect household contacts.