Miracle-dz/UniFAR-FTUs huggingface dataset:
Body experience influences lexical-semantic knowledge of body parts in children with hemiplegic cerebral palsy

Background Disorders in different levels of body representation (i.e., body schema, body structural description, and body image) are present in hemiplegic cerebral palsy (HCP). However, it remains unclear whether the body image develops from aspects of body schema and body structural description, and how this occurs in children with HCP. Objective and methods In a cross-sectional study, we investigated 53 children with HCP (mean age about 10 years) and 204 typically developing (TD) control children to qualitatively evaluate whether and how body schema (related sensorimotor experiences) and body structural description (related visuospatial experiences) affect the development of children’s body image and whether this development is delayed through HCP. Graph analysis was used to create a lexical-semantic map of body representation from data of a semantic word fluency task. Results Results indicated a similar qualitative pattern of influences of sensorimotor and visuospatial experiences on lexical-semantic knowledge of body parts, with a delayed developmental course in children with HCP compared to TD children. Conclusion These findings suggest that children’s body image seemed to be influenced by body schema and body structural descriptions as indicated by poorer lexical-semantic knowledge of body parts in children with HCP due to missing physical experiences of the affected body parts. This might imply that “body talk” may beneficially complement physical therapy for children with HCP to promote body image development.
Basins of attraction of chimera states on networks

Networks of identical coupled oscillators display a remarkable spatiotemporal pattern, the chimera state, where coherent oscillations coexist with incoherent ones. In this paper we show quantitatively in terms of basin stability that stable and breathing chimera states in the original two coupled networks typically have very small basins of attraction. In fact, the original system is dominated by periodic and quasi-periodic chimera states, in strong contrast to the model after reduction, which can not be uncovered by the Ott-Antonsen ansatz. Moreover, we demonstrate that the curve of the basin stability behaves bimodally after the system being subjected to even large perturbations. Finally, we investigate the emergence of chimera states in brain network, through inducing perturbations by stimulating brain regions. The emerged chimera states are quantified by Kuramoto order parameter and chimera index, and results show a weak and negative correlation between these two metrics.
Prevalence of cryptococcal meningitis among people living with human immuno-deficiency virus and predictors of mortality in adults on induction therapy in Africa: A systematic review and meta-analysis

Background Cryptococcal meningitis (CM) is a leading cause of adult meningitis in countries with a high burden of HIV. It has remained a significant cause of morbidity and mortality in Africa despite the extensive rollout of HIV antiretroviral therapy (ART). This study aimed to systematically synthesize the evidence on the prevalence of CM among people living with HIV (PLWH) and its predictors of mortality among adults who are on induction antifungal therapy in Africa. Methods PubMed/MEDLINE, Embase, and Google Scholar were searched for randomized clinical trials or observational studies published in Africa from 1995 to April 2021. Pooled prevalence of CM among PLWH was calculated using R-studio Version 1.4. 1717 software and the data extracted from eligible studies were pooled as percentage with a 95% confidence interval (CI). Predictors of mortality among adults on induction antifungal therapy were synthesized narratively. Results Out of 364 studies identified, 17 eligible articles were included in the analysis. The prevalence of CM among PLWH in Africa was 5.11% (95% CI 2.71–9.43%; participants = 10,813; studies = 9; I2 = 97%). In the subgroup analysis, the prevalence was 12.9% (95% CI 4.883–30.0; participants = 533; studies = 3; I2 = 63%) in the years 1995–2010 and 3.18% (95% CI 1.54–6.45; participants = 10,280; studies = 6; I2 = 98%) in the years 2011–2021, with the prevalence significantly decreased by 51% (p = 0.02). Predictors of mortality were fluconazole monotherapy, focal neurological signs, low Glasgow coma scale, and delayed diagnosis of CM at varied timepoint. Conclusion Prevalence of CM has significantly decreased from 1996–2010 to 2011–2021 among PLWH on induction therapy in Africa. Fluconazole monotherapy, focal neurological symptoms, diastolic blood pressure < 60 mmHg, and concurrent tuberculosis coinfection were significant predictors of mortality at 2- and 10-weeks timepoints. CM remains a major concern among PLWH despite increases in ART coverage. Improved access to effective antifungal therapies is needed in Africa for timely initiation of combination induction therapy and better treatment outcomes of PLWH. Systematic review registration [https://www.crd. york.ac. uk/prospero/display_record. php? RecordID=254113], identifier [CRD42021254113].
Merging the Psychophysical Function With Response Times for Auditory Detection of One vs. Two Tones

The purpose of this study is to take preliminary steps to unify psychoacoustic techniques with reaction-time methodologies to address the perceptual mechanisms responsible for the detection of one vs. multiple sounds. We measured auditory redundancy gains for auditory detection of pure tones widely spaced in frequency using the tools of Systems Factorial Technology to evince the system architecture and workload capacity in two different scenarios (SOFT and LOUD). We adopted an experimental design in which the presence or absence of a target at each of two frequencies was combined factorially with two stimulus levels. Replicating previous work, results did not allow an assessment of system architecture due to a failure to observe factor influence at the level of distribution ordering for dual-target stimuli for both SOFT and LOUD scenarios. All subjects demonstrated very modest redundancy gains for the dual-target compared to the single-target stimuli, and results were similar for both LOUD and SOFT. We propose that these results can be predicted by a mental architecture that falls into the class of integrated subadditive parallel systems, using a well-supported assumption that reaction time is driven by loudness. We demonstrate that modeled loudness of the experimental sounds (which ranged between about 0.2 and 14 sones) is highly correlated with mean reaction time (r = −0.87), and we provide a proof-of-concept model based on Steven’s Power law that predicts both a failure of distributional ordering for dual-target stimuli and very modest redundancy gains.
The impact of morally injurious events in a refugee sample: A quantitative and qualitative study

Background Posttraumatic Stress Disorder (PTSD) is often reported by refugees that faced violence and persecution. Some stressful events may also entail moral conflicts or dilemmas, described as “potentially morally injurious events” (PMIE). Very few studies have yet investigated the nature of these PMIEs in traumatized refugees, using both quantitative and qualitative data. Method For this retrospective study, secondary data analysis was used to examine the traumatic events of 183 patients. Based on established definitions of a PMIE, participants were allocated to a Moral Injury (MI) group if they reported lasting distress after exposure to an event of which they indicated that it transgressed their moral beliefs. The remaining participants were allocated to the No-MI group. The type of PMIEs was categorized using qualitative analysis. The groups were compared in terms of PTSD severity, feelings of guilt, and general mental health symptoms. Results Of the total sample, 55 participants reported one or more acts of transgression (MI group) and 128 reported no acts of transgression (No-MI group). Analyses of PMIEs revealed six themes 1) failing to prevent harm to others, 2) not giving aid to people in need, 3) leaving family members behind that consequently lead to injury or death of others, 4) making indirect and direct moral decisions leading to injury or death of others, 5) betrayal, and 6) engaging in the harm of others. No differences were found between groups on the clinical outcomes, except for feelings of guilt. Conclusion A considerable number of traumatized refugees reported confrontation with PMIEs. Experiencing PMIEs appeared unrelated to elevated posttraumatic mental health issues.
A Metric for Quantifying UWB Ranging Error Due to Clock Drifts

Wireless ranging, where two or more wireless devices determine their relative distance by exchanging messages, is a fundamental primitive in short-range distance measurements and localization. These methods are used by fine-time measurement in WiFi, and ultra-wideband (UWB) radios which is seeing an uptick in the smartphone market. Since ranging depends on accurate timestamps, the clock drifts between devices is an important consideration that affects ranging precision. Several applications have been proposed in the short-range localization context with their own ranging protocols and almost all of them perform clock-drift analysis to assess the quality of the protocol and ranging formulation. Although this is standard practice, there lacks a way to quantify and compare the extent of clock-drift introduced measurement errors. In this work, we introduce a metric based on numerical simulations that enables direct comparisons across schemes, and demonstrate how it helps analyze distance measurement errors.
Provenance and Logging for Sense Making

Sense making is one of the biggest challenges in data analysis faced by both the industry and the research community. It involves understanding the data and uncovering its model, generating a hypothesis, selecting analysis methods, creating novel solutions, designing evaluation, and also critical thinking and learning wherever needed. The research and development for such sense making tasks lags far behind the fast-changing user needs, such as those that emerged recently as the result of so-called “Big Data”. As a result, sense making is often performed manually and the limited human cognition capability becomes the bottleneck of sense making in data analysis and decision making. One of the recent advances in sense making research is the capture, visualization, and analysis of provenance information. Provenance is the history and context of sense making, including the data/analysis used and the users’ critical thinking process. It has been shown that provenance can eﬀectively support many sense making tasks. For instance, provenance can provide an overview of what has been examined and reveal gaps like unexplored information or solution possibilities. Besides, provenance can support collaborative sense making and communication by sharing the rich context of the sense making process. Besides data analysis and decision making, provenance has been studied in many other ﬁelds, sometimes under diﬀerent names, for diﬀerent types of sense making. For example, the Human-Computer Interaction community relies on the analysis of logging to understand user behaviors and intentions; the WWW and database community has been working on data lineage to understand uncertainty and trustworthiness; and ﬁnally, reproducible science heavily relies on provenance to improve the reliability and eﬃciency of scientiﬁc research. This
SCA 2009-43 1 / 6 IS WETTABILITY ALTERATION OF CARBONATES BY SEAWATER CAUSED BY ROCK DISSOLUTION ?

INTRODUCTION In a series of studies, Austad and co-workers [1-5] have documented that seawater at high temperatures is able to modify the wetting conditions of chalk towards more waterwet conditions, and in that way seawater can act as a “Smart” EOR fluid. Through systematic experimental studies, it was verified that Ca, Mg, and SO4 were the active ions in the wettability alteration process. Studies by BP at complete reservoir conditions for the Valhall field have confirmed the results [6]. It was documented by Zeta potential measurements that these ions acted as potential determining ions towards chalk, i.e. they were able to adsorb onto the chalk surface and modify the surface charge. The mutual interaction between SO4 and Ca at various temperatures is clearly illustrated by Fig. 1a and b. Thus, as long as both anionic and cationic potential determining ions are present in solution, the Zeta potential will not change very much as the temperature is increased, but the reactivity of the actual ions increases [7].
Measurement of Branching Fractions and CP and Isospin Asymmetries in B ->K* gamma

We present a preliminary analysis of the decays B0 ->K*0 gamma and B+ ->K*+ gamma using a sample of 383 x 10^6 BBbar events collected with the BABAR dector at the PEP-II asymmetric energy B factory. We measure the branching fractions BF(B0 ->K*0 Gamma) = (4.58 +/- 0.11 +/- 0.16) x 10^-5 and BF(B+ ->K*+ Gamma) = 4.73 +/- 0.15 +/- 0.17 x 10^-5. We measure the direct CP asymmetry to be -0.043<A(B ->K* gamma)<0.025 and the isospin asymmetry to be -0.021<Delta0-<0.079, where the limits are determined at the 90% confidence interval and include both the statistical and systematic uncertainties.
Assessment of the Correlation between the Levels of Physical Activity and Technology Usage among Children with Down Syndrome in the Riyadh Region

Background: Children with Down Syndrome (C-DS) have language, cognitive and communication difficulties, in addition to consistent physical inactivity that contributes to poor health and higher-disability-adjusted life years. The purpose of this study was to determine the correlation between the use of electronic technology and levels of physical activity in C-DS in the Riyadh region of Saudi Arabia. Methods: A cross-sectional study was conducted with 49 mothers, where each had a child (6–12 years of age) with Down Syndrome (DS), and who were recruited using purposive sampling from three DS centers in Riyadh, Saudi Arabia. The Children’s Physical Activity Questionnaire and Research Questionnaire on the Impact of Technology on Children were used. Descriptive statistics were used to describe the demographics. Pearson’s correlation, Student’s t-test and the Chi-square test were used to assess the association between technology use, physical activity levels and socio-demographic variables. Results: There was no significant correlation between physical activity and the use of technology by C-DS. However, there was a negative correlation between a high level of physical activity and technology use (R = −0.037). Although, no significant correlation between the mother’s characteristics and technology use was found; there was a significantly positive correlation (p = 0.05) between the education level of mothers and the technology use by C-DS. Nonetheless, there was no association between the physical activity level and the gender of the child with DS. Conclusions: This study found that no significant relationship exists between the use of electronic gadgets and the level of physical activity in C-DS.
Combining ability analysis for yield and some quality traits in spring wheat (Triticum aestivum L.)

Combining ability analysis was studied in a 10 × 10 diallel cross of spring wheat (Triticum aestivum L.). The analysis of variance for combining revealed that the variance due to gca and sca were highly significant for all the characters indicated that both the additive and non-additive gene actions were involved in the expression of the traits. The genotypes WH 1094, PBW 590 and PBW 373 were considered as the best general combiners, while hybrids DBW 58 x DBW 17, PBW 550 x PBW 373, MP 1236 x PBW 373, WH 1094 x PBW 590, PBW 590 x PBW 373, RAJ 3765 x HD 2687, PBW 590 x WH 711, MP 1236 x PBW 550, RAJ 3765 x DBW 58, HD 2687 x WH 711 and MP 1236 x WH 1094 as good specific combinations for grain yield and other yield contributing and quality traits. The promising parents namely PBW 373, PBW 590 and WH 1094 which are having high gca effects in desirable direction for yield components and for quality traits may be incorporated in crossing programme to have better genotypes for yield better and quality. The crosses PBW 550 x PBW 373, MP 1236 x PBW 373, WH 1094 x PBW 590, MP 1236 x PBW 550 and RAJ 3765 x DBW 58 which showed good sca effects for major yield and more than six yield components characters were also found superior for gluten content, ash content and showed low reaction of phenol on the grains, may be exploited for better yield and chapati quality either by exploiting them through heterosis breeding or involving them in multiple cross breeding programme for obtaining transgressive segregants and broad genetic base population in wheat for improvement in yield.
Social position and personal versus social focus: A multinational study of managerial values

Managerial positions involve influencing others, hence the importance of studying the standards guiding managers' attitudes, decisions, and behavior. Drawing on structural theories and psychological findings on the effects of subjective social status, we predict that holding a managerial position is related to individual value structure via self-perceived social rank of those in managerial positions. We argue that holding a managerial position is associated positively with prioritizing values reflecting personal focus (self-enhancement and openness to change value types) and, as a consequence, negatively with prioritizing values reflecting social focus (self-transcendence and conservation value types). Using data from the European Social Survey 2012 (N = 48,105) from 29 countries, we found a mediating effect of subjective social status between holding a managerial position and personal versus social focus not moderated by the country context. We discuss the implications of these findings for psychological theories of social hierarchy and managerial practice.
Dimethyl Fumarate Ameliorates Paclitaxel-Induced Neuropathic Pain in Rats

Background Paclitaxel (PTX)-induced peripheral neuropathy (PIPN) is nonresponsive to the currently available analgesics. Previous studies have shown the role of oxidative stress and central sensitization in the development of peripheral neuropathy. Dimethyl fumarate (DMF) acts as a nuclear factor erythroid-2-related factor 2 (Nrf2) activator with neuroprotective benefits and is approved for use in multiple sclerosis. Materials and methods In the current research, we evaluated the efficacy of DMF on paclitaxel-induced peripheral neuropathy in rats. Every alternate day for one week, paclitaxel 2 mg/kg dose was injected to establish a rat model of PIPN. Animals were treated with 25 mg/kg and 50 mg/kg of DMF. All the animals were assessed for thermal hyperalgesia, cold allodynia, and mechanical allodynia once a week. The gene expression of Nrf2 and the levels of pro-inflammatory mediators (interleukin (IL)-6, tumor necrosis factor-alpha (TNF-α), and IL-1β) were quantified in the sciatic nerves of these rats. The levels of p38 mitogen-activated protein kinase (MAPK) and brain-derived neurotrophic factor (BDNF) were quantified in the dorsal horn of the spinal cord. Results DMF significantly attenuated paclitaxel-induced thermal hyperalgesia and cold/mechanical allodynia. A significant decrease in the levels of pro-inflammatory cytokines with the levels of p38 MAPK and BDNF was observed in the DMF-treated animals. DMF treatment significantly upregulated the gene expression of Nrf2 in the sciatic nerve. Conclusion These findings suggest that DMF prevented the development of PIPN in rats through the activation of Nrf2 and the inhibition of p38 MAPK and BDNF.
Boundary Behavior of Holomorphic Functions of Several Complex Variables.

This book has as its subject the boundary value theory of holomorphic functions in several complex variables, a topic that is just now coming to the forefront of mathematical analysis. For one variable, the topic is classical and rather well understood. In several variables, the necessary understanding of holomorphic functions via partial differential equations has a recent origin, and Professor Stein's book, which emphasizes the potential-theoretic aspects of the boundary value problem, should become the standard work in the field.Originally published in 1972.The Princeton Legacy Library uses the latest print-on-demand technology to again make available previously out-of-print books from the distinguished backlist of Princeton University Press. These paperback editions preserve the original texts of these important books while presenting them in durable paperback editions. The goal of the Princeton Legacy Library is to vastly increase access to the rich scholarly heritage found in the thousands of books published by Princeton University Press since its founding in 1905.
Circ_0040929 Serves as Promising Biomarker and Potential Target for Chronic Obstructive Pulmonary Disease

Background Circular RNAs (circRNAs) can act as essential regulators in many diseases, including chronic obstructive pulmonary disease (COPD). We aimed to explore the role and underlying mechanism of circ_0040929 in COPD. Methods A cellular model of COPD was constructed by treating human bronchial epithelial cells (16HBE) with cigarette smoke extract (CSE). The levels of circ_0040929, microRNA-515-5p (miR-515-5p) and insulin-like growth factor-binding protein 3 (IGFBP3) were measured by quantitative real-time PCR. Cell proliferation was assessed by Cell Counting Kit-8 and 5-ethynyl-2’-deoxyuridine assays. Cell apoptosis was evaluated by flow cytometry. Protein expression was measured using Western blot assay. The levels of inflammatory factors and airway remodeling were assayed via enzyme-linked immunosorbent assay. The interaction between miR-515-5p and circ_0040929/IGFBP3 was confirmed by dual-luciferase reporter, RNA pull-down and RNA immunoprecipitation assays. Exosomes were detected using transmission electron microscopy. Results Circ_0040929 expression and IGFBP3 expression were upregulated in the serum of smokers (n = 22) compared to non-smokers (n = 22) and more significantly upregulated in the serum of COPD patients (n = 22). However, miR-515-5p expression was decreased in the serum of smokers compared to non-smokers and further reduced in the serum of COPD. Circ_0040929 knockdown attenuated CSE-induced cell injury by increasing proliferation and reducing apoptosis, inflammation, and airway remodeling in 16HBE cells. MiR-515-5p was a direct target of circ_0040929, and miR-515-5p inhibition reversed the effect of circ_0040929 knockdown in CSE-treated 16HBE cells. IGFBP3 was a direct target of miR-515-5p, and miR-515-5p overexpression alleviated CSE-induced cell injury via targeting IGFBP3. Moreover, circ_0040929 regulated IGFBP3 expression by targeting miR-515-5p. Importantly, circ_0040929 was upregulated in serum exosomes from COPD patients. Conclusion Circ_0040929 played a promoting role in CSE-induced COPD by regulating miR-515-5p/IGFBP3 axis, suggesting that it might be a novel potential target for COPD treatment.