Miracle-dz/UniFAR-FTUs huggingface dataset:
Predictive Value of Urinalysis and Recent Antibiotic Exposure to Distinguish Between Bacteriuria, Candiduria, and No-Growth Urine

Purpose Urinary tract infections are diagnosed by clinical symptoms and detection of causative uropathogen. Antibiotics are usually not indicated in candiduria and no-growth urine. We aimed to develop a predictive score to distinguish bacteriuria, candiduria, and no-growth urine, and to describe the distribution of microorganisms in urine. Patients and Methods A single-center, retrospective cohort study was conducted between January 2017 and November 2017. Patients with concomitant urinalysis and urine culture were randomly sorted for a clinical prediction model. Multivariable regression analysis was performed to determine factors associated with bacteriuria, candiduria, and no-growth urine. A scoring system was constructed by rounding the regression coefficient for each predictor to integers. Accuracy of the score was measured by the concordance index (c-index). Results There were 8091 positive urine cultures: bacteria 85.6%, Candida 13.7%. Randomly selected cases were sorted into derivation and validation cohorts (448 cases and 272 cases, respectively). Numerous yeast on urinalysis predicted candiduria with complete accuracy; therefore, it was excluded from a score construction. We developed a NABY score based on: positive nitrite, 1 point; Antibiotic exposure within 30 days, –2 points; numerous Bacteria in urine, 2 points; few Yeast in urine, –2 points; moderate Yeast in urine, –5 points. The c-index was 0.85 (derivation) and 0.82 (validation). A score ≥0 predicted 76% and 54% of bacteriuria in the derivation and validation cohorts, respectively. A score ≤−3 predicted 96% of candiduria in both cohorts. Conclusion Numerous yeast on urinalysis and the NABY score may help identify patients with a low risk of bacteriuria in whom empiric antibiotics for UTIs can be avoided.
MORSE: mesoscale ocean radar signature experiments

The MORSE project is devoted to furthering the understanding of the imaging of the ocean surface by synthetic aperture radar (SAR) in the presence of internal waves. The research is being undertaken by a Consortium of four University and two commercial partners under the MAST III initiative of the CEC, Brussels. Work on the 3-year project started on 1st February 1996. A tank experiment is undertaken using the European (Coriolis) facility at the Joseph Fourier University, Grenoble. The tank water surface will be imaged by a new W-band radar built by the Department of Electronic and Electrical Engineering, University College, London. The images will be compared and contrasted with SAR ocean imagery from satellites such as ERS-1 and 2 or Radarsat. There is still much uncertainty relating to how one might extract useful information from such SAR imagery of the ocean surface. Not least of the remaining problems is how the ocean surface is actually imaged at the various wavelengths used by the radars, and how that imaging process depends on polarisation, angle of incidence, height above the ocean, speed of motion of the viewing aperture with respect to the ocean surface etc. Of particular concern is understanding of the dependency of the imaging process on the radar wavelength at lengths in the one centimetre range. To this end, the W-band radar is to be built. Operating at a wavelength of 3 mm, it will probe the tank water surface at capillary wavelengths, a region in which very little, if any, SAR imagery is available and in which the capillary waves are known to be considerably steep. Comparison of a variety of images, radars, image formation mechanisms and image modelling results are to be made, especially in those situations which involve the straining of the tank and ocean surface by currents, with particular emphasis on currents induced by internal waves.
Ethnic Identity, Individual Identity, and Perceived Stress Correlated with Life Satisfaction of American College Students

On the basis of previous and recent research on college life and school education it is hypothesized that both individual or personal identity (i.e., individual self-esteem) and ethnic or social identity (i.e., group/collective self-esteem) play a very important role in life satisfaction of college students. A total of 186 college students completed different inventories containing items concerning life satisfaction. The results revealed that individual or personal identity, ethnic or social identity, and perceived stress largely accounted for the variance of college students’ life satisfaction. In addition, the differences between White or Euro-American, Hispanic/Latino/a, African, Asian, and other students were also found to be significant in terms of their college life satisfaction, personal identity, social identity, locus of control, residence or living conditions, and pessimistic attitudes toward racial problems.
Mutational landscape of primary and recurrent Ewing sarcoma

Introduction Ewing sarcoma (ES) is a highly aggressive malignancy of bone and soft tissues characterized by the presence of a genetic fusion involving the EWSR1 gene. More than one-third of patients develop distant metastases, which are associated with unfavorable prognosis. Knowledge about the disease’s genetic landscape may help foster progress in using targeted therapies in the treatment of ES. Aim of the study The objective is to assess the mutational landscape of ES in pretreatment samples, tumor samples after neoadjuvant chemotherapy, and in metastatic/recurrent tumors in children and adults Material and methods DNA from 39 formalin-fixed paraffin-embedded tumor samples of 22 patients (17 adults, 5 children) were analyzed by targeted next generation sequencing (NGS) using the Oncomine Comprehensive Assay v3gene panel. Additional functional analyses were performed between patient subgroups. Results All samples were characterized by low tumor mutation burden (< 10 mut/Mb). The most commonly mutated genes were PIK3R1 (59%) and POLE (50%). The most widely detected variants in biopsy samples were PIK3R1 T369I (50%), FGFR1 E159K, and TP53 at codon 72 (both in 27.3%). Additionally, the ATR,BRCA1, RAD50,ATM,CHEK1, and NBN genes showed a significantly higher number of mutations in ES. Mutations in PIK3R1 were significantly more frequent in adults, while mutations in the pathways responsible for cell cycle control, DNA repair, and transcriptional regulation were more frequent in children. Conclusions Besides EWSR1 fusion, ES is characterized by numerous point mutations that are potential targets for precision medicine. There is high genomic heterogeneity that may explain differences in outcomes between patient subgroups.
THE RELATIONSHIP BETWEEN FRAILTY AND SARCOPENIA IN OLDER ADULTS WITH CANCER

Materials and Methods: This cross-sectional, descriptive study included 204 geriatric cancer patients who were admitted to the Chemotherapy Day Unit of a university hospital and who met the study’s inclusion criteria. The Descriptive Characteristics Questionnaire, Modified Charlson Comorbidity Index, and Edmonton Frail Scale were used as data collection tools. A body composition analyzer, a hand dynamometer, a stopwatch, a stadiometer, and a tape measure were used to determine the presence of sarcopenia.
Development of the Writing Process from Primary to Secondary Education

The aim of this study was to analyse the differences that arise between different educational levels in the writing process and product, and in the variables moderating writing, using an online technique of immediate retrospection. Participants consisted of 1,231 students presenting normal academic performance and attending compulsory education from the 4th year of Primary Education to the 4th year of Secondary Education. The results show that although students in their final year of compulsory Secondary Education (CSE) comprised the group which obtained the best outcomes, development from Primary Education (PE) was not as steady as might be expected. Engagement in the writing process was observed to diminish at the start of CSE, and there were more interruptions during the first phase of the process and less engagement in planning and producing a written text. Data on the variables modulating writing indicate that inexperienced writers presented more positive attitudes and a greater motivation to write and overestimated their self-efficacy, indicative of having less knowledge, practice and expertise in the process, product and quality of writing. These results suggest that the orchestration of younger students’ writing process during the production of a written text is not the most suitable, and results in lower quality. The implications, limitations and future perspectives are discussed.
Measuring the Satisfaction of Participants in Online Learning during the COVID-19 Pandemic: A Large-Scale Analysis

With the rapid deterioration and widespread of COVID-19, educational institutions around the world have adopted online teaching instead of traditional classroom teaching for uninterrupted learning. Under the large-scale online teaching activities with COVID-19, participant satisfaction needs to be explored. We collected the data of over five million students and parents, as well as nearly a half million teachers’ data. For students and teachers, our results show that regions, grades, urban and rural areas have different impacts on satisfaction. For parents, we adopt machine learning and statistical methods to investigate factors affecting satisfaction. In this research, we found some potential problems of participants groups with different characteristics, including technical support, learning resources, and online interaction. At last, this paper puts forward some suggestions on these finding problems. The government’s education institutions can make special policies according to different situations.
Prediction of Alzheimer's Disease Based on Coordinate-Dense Attention Network

Alzheimer’s disease (AD) is a degenerative disease of the nervous system. Mild cognitive impairment (MCI) is a condition between brain aging and dementia. The prediction will be divided into stable sMCI and progressive pMCI as a binary task. Structural magnetic resonance imaging (sMRI) can describe structural changes in the brain and provide a diagnostic method for the detection and early prevention of Alzheimer’s disease. In this paper, an automatic disease prediction scheme based on MRI was designed. A dense convolutional network was used as the basic model. By adding a channel attention mechanism to the model, significant feature information in MRI images was extracted, and the unimportant features were ignored or suppressed. The proposed framework is compared with the most advanced methods, and better results are obtained.
The ambivalent link between globalisation and socio-economic rights in post-apartheid South Africa: Making a case for the right to adequate houses

ABSTRACT This paper examines the extent to which globalisation has affected the post-apartheid state’s ability to fulfil the right to adequate houses enshrined in the South African Constitution (Act 108 of 1996). Underpinned by the rights-based approach to development (RBAD) which provides a mechanism to promote, protect, and fulfil various rights, the study employed a quantitative methodology. A survey was the preferred data collection method and a questionnaire was used as the data collection instrument. The probability sampling technique of random cluster sample was used in the study and the Statistical Package for the Social Sciences (SPSS) was used to analyse questionnaires focusing primarily on descriptive statistics. The sample size consisted of 500 survey respondents selected from two towns in the Buffalo City Metropolitan Municipality in the Eastern Cape Province. We used an alpha level of . 05 for all statistical tests. The study was premised on the following null hypothesis (H0): the right to housing is equally distributed among the population. The findings indicate that the right to houses is not equally distributed among the population, X2 (2, N = 500) = 56.37, p < . 05. Therefore, the null hypothesis (H0) is rejected. We can conclude, therefore, that there is a statistically significant difference amongst the groups.
Octane appetite:The Relevance of a Lower Limit to the MON Specification in a Downsized, Highly Boosted DISI Engine

Market demand for high performance gasoline vehicles and increasingly strict government emissions regulations are driving the development of highly downsized, boosted direct injection engines. The in-cylinder temperatures and pressures of these emerging technologies tend to no longer adhere to the test conditions defining the RON and MON octane rating scales. This divergence between fuel knock rating methods and fuel performance in modern engines has previously led to the development of an engine and operating condition dependent scaling factor, K, which allows for extrapolation of RON and MON values. Downsized, boosted DISI engines have been generally shown to have negative K-values when knock limited, indicating a preference for fuels of higher sensitivity and challenging the relevance of a lower limit to the MON specification. The Ultraboost engine is an inline-4 downsized, highly boosted prototype DISI engine designed to achieve a 35% reduction in CO2 emissions whilst maintaining performance of a production V8. A series of 14 fuel formulations were tested to probe engine response to various fuel properties. This paper presents results from a 7 fuel RON and MON decorrelated matrix at four high-load engine conditions. The K-value was found to be negative at all engine conditions; fuels of higher sensitivity were found to yield improved engine performance. Furthermore, in-cylinder experimental data from high load knocking conditions with a single standard octane fuel were used to simulate the K-value; a similar trend between theory and experiment was observed.
Transition Points of Heart Rate during a Progressive Maximal Intermittent Field Test in Young Soccer Players

Ferreira-Junior AJ, Zanetti GG, Couto PG, Bastos LALG, Silva SF, Lima JRP, De-Oliveira FR. Transition Points of Heart Rate during a Progressive Maximal Intermittent Field Test in Young Soccer Players. JEPonline 2012;15(3):81-88. The purpose of this study was to identify the heart rate inflection point (HRIP) and the heart rate deflection point (HRDP) during a progressive maximal intermittent field test (TCar) in the 29 young soccer players. In order to identify the transition points, the differences of the heart rate (HR) values derived from linear and polynomial fits using all HR points were calculated. We were able to identify the HRIP in just three subjects (76 ± 1% of HR max and 77 ± 2% of Peak Velocity). The HRDP was identified in all the subjects (92% ± 2% of HR max and 84 ± 4% of Peak Velocity). The reduced number of identifications for HRIP was probably due the elevated values of HR in the first stage of TCar (149 ± 12 beats·min -1 ). Thus, using the original TCar protocol, it is possible to ident ify the HRDP. However, for studies using HRIP, it should be used with a smaller initial load in the test.
Bioinformatics analysis identifying FBXO45 gene as a potential oncogene in esophageal cancer.

Background F-box protein 45 (FBXO45) is a member of the F-box protein family, and is reportedly involved in the progression of many diseases. However, its role in esophageal cancer (ESCA) remains unclear. Methods The expression, clinical characteristics, gene function, pathway, and correlation between the infiltration of different immune cells were analyzed using public data. The pan-cancer expression of FBXO45 was assessed using the TIMER2 database. The expression of FBXO45 in different tumor stages and histology subtypes were evaluated using the UALCAN database. The protein-protein interaction (PPI) network was constructed using the STRING database. Immune cell infiltration data were downloaded from the ImmuCellAI database. Results The top 300 genes most positively correlated with FBXO45 were screened into the enrichment analysis. The functional enrichment results showed that FBXO45 was mainly associated with proteasomal protein catabolic process and the regulation of DNA metabolic processing in the biological process (BP) category; spindle, chromosomal region, and focal adhesion in the cellular component category; and ATPase activity and ubiquitin-protein transferase activity terms in the molecular function category. FBXO45 was overexpressed in ESCA and other cancer types. FBXO45 expression was positively associated with the infiltration levels of immunosuppressive cells, such as CD8+ (cluster of differentiation 8+) T cells and NK (natural killer cell) cells, in ESCA. MYCBP2 and SKP1 were most associated with FBXO45. Conclusions Our results suggested that FBXO45 is a potential oncogene in ESCA. Elevated FBXO45 expression indicates a relatively immunosuppressive microenvironment.
Using improved genetic algorithms to facilitate time-cost optimization

Time-cost optimization problems in construction projects are characterized by the constraints on the time and cost requirements. Such problems are difficult to solve because they do not have unique solutions. Typically, if a project is running behind the scheduled plan, one option is to compress some activities on the critical path so that the target completion time can be met. As combinatorial optimization problems, time-cost optimization problems are suitable for applying genetic algorithms (GAs). However, basic GAs may involve very large computational costs. This paper presents several improvements to basic GAs and demonstrates how these improved GAs reduce computational costs and significantly increase the efficiency in searching for optimal solutions.
Heritage and the Post-Socialist City: Social and Cultural Perspectives

Heritage and the Post-Socialist City: Social and Cultural PerspectivesThe paper is a presentation of the latest volume of Colloquia Humanistica. The leading subject of heritage in the post-socialist city is largely commented on with reference to three major questions: the interplay of city planning and identity issues; symbolic practices and semiotic shifts in urban space; social practices and the functioning of local social networks. Concluding remarks draw attention to the intersection of memory studies and politics, as well as the issue of (dis)continuity, which is crucial for the stability and security of societies on the one hand, and for efficient change on the other. Dědictví a postsocialistické město: sociologická a kulturní perspektivaPříspěvek je prezentací nejnovějšího čísla Colloquia Humanistica. Jeho hlavní téma dědictví v postsocialistických městech je z velké části komentováno s odkazem na tři hlavní otázky týkající se podoby: vztahu mezi městským plánováním a otázkami identity; symbolických praktik a sémiotických posunů v městském prostoru; a sociálních praktik a fungování místních sociálních sítí. Závěrečné poznámky poukazují na průnik studia paměti a politiky, stejně jako na otázku (dis)kontinuity, klíčové na jedné straně pro stabilitu a bezpečnost společnosti, a na straně druhé pro její efektivní změnu. Dziedzictwo i miasto postsocjalistyczne w perspektywie socjologicznej i kulturowejArtykuł jest prezentacją najnowszego numeru „Colloquia Humanistica”. Główny temat dziedzictwa w miastach postsocjalistycznych został przedstawiony w odniesieniu do trzech zasadniczych pól tematycznych: relacji między planowaniem miejskim a kwestiami tożsamościowymi, praktyk symbolicznych i zachowań semiotycznych w przestrzeni miejskiej oraz praktyk w kontekście tworzenia się lokalnych sieci społecznych. Wnioski wskazują na wpływ pamięci oraz polityki, jak też kwestii (nie) ciągłości, na stabilność i bezpieczeństwo wspólnot miejskich z jednej strony, jak też na ich skuteczne przemiany z drugiej.
Isokinetic evaluation of trunk muscles in healthy and low back pain subjects

Chronic low back pain constitutes a major healthcare problem in industrialised countries and has been found to be associated with certain anthropometric, postural, muscular and mobility characteristics (Bayramoglu et al. 2001). Among these, poor abdominal muscle strength and an imbalance between flexor and extensor trunk muscle strength seem to be linked (Pope et al. 1985). These factors cannot be accurately evaluated with conventional means such as non-apparatus tests which are non-discriminating. Isokinetic apparatuses have been adapted for this purpose and are of practical interest in the follow-up of such patients (Calmels et al. 2004). The force–velocity relationship provides a general overview of the individual muscle properties. Until now, influence of lower back pain on this relationship has not been studied. The purpose of the present study was (i) to describe the torque– and power–velocity relationships of the trunk muscles in chronic low back pain patients and (ii) to compare them with those of healthy subjects. In addition, the flexor/extensor ratio of the trunk muscles was determined to verify whether it is predictive of chronic low back pain.
Tourist Perception of the Value of Time on Holidays: Implications for the Time Use Rebound Effect and Sustainable Travel Practice

Technological solutions to achieve energy efficiency and carbon reduction in tourism are unlikely to be sufficient alone. This is partly because of the rebound effect (RE) where consumer behavior can absorb some of or all the energy efficiency gains. Time savings from time-efficient technologies can intensify energy consumption, leading to the time use rebound effect (TRE). Research suggests that the TRE in tourism can be high, especially in relation to tourist travel, but its understanding is limited. This study aims to provide empirical evidence of the TRE by categorizing tourist groups that are most prone to its occurrence. An exploratory sequential mixed methods approach is employed. Key factors that influence the potential TRE occurrence include socio-demographic characteristics, holiday preferences, time/money availability, time perception/attitudes, and time use patterns on holiday. The “Busy explorer” cluster of tourists is most likely to show TREs. Implications and suggestions for future research are outlined.
High-gain mode-adapted semiconductor optical amplifier with 12.4-dBm saturation output power at 1550 nm

A mode-adapted semiconductor optical amplifier (SOA) has been fabricated and packaged. At the gain peak, 1500 nm, the fiber to fiber gain was measured to be 32.5 dB. Statistics for eight packaged devices indicate that a fiber-to-fiber gain of 26.3 dB /spl plusmn/ 1.3 dB and a saturation output power of 12.4 dBm /spl plusmn/ 0.4 dBm are typical at a bias of 500 mA for /spl lambda/ = 1550 nm. Polarization sensitivity at 1550 nm was measured to be 1.1 dB /spl plusmn/ 0.4 dB and the transverse electric (TE) polarization state noise figure (NF) was determined to be 7.0 dB /spl plusmn/ 0.5 dB. The coupling loss was 1.3 dB /spl plusmn/ 0.1 dB per facet. This SOA, with a 1.3-nm filter, was used as an optical preamplifier in a 10-Gb/s return-to-zero (RZ) system testbed with a pseudorandom binary sequence (PRBS) of 2/sup 31/ -1. A 14.5-dB improvement in receiver sensitivity was observed at a bit error rate (BER) of 10/sup -11/.