Miracle-dz/UniFAR-FTUs huggingface dataset:
A statistical interpolation code for ocean analysis and forecasting

We present a data assimilation package for use with ocean circulation models in analysis, forecasting and system evaluation applications. The basic functionality of the package is centered on a multivariate linear statistical estimation for a given predicted/background ocean state, observations and error statistics. Novel features of the package include support for multiple covariance models, and the solution of the least squares normal equations either using the covariance matrix or its inverse - the information matrix. The main focus of this paper, however, is on the solution of the analysis equations using the information matrix, which offers several advantages for solving large problems efficiently. Details of the parameterization of the inverse covariance using Markov Random Fields are provided and its relationship to finite difference discretizations of diffusion equations are pointed out. The package can assimilate a variety of observation types from both remote sensing and in-situ platforms. The performance of the data assimilation methodology implemented in the package is demonstrated with a yearlong global ocean hindcast with a 1/4°ocean model. The code is implemented in modern Fortran, supports distributed memory, shared memory, multi-core architectures and uses Climate and Forecasts compliant Network Common Data Format for Input/Output. The package is freely available with an open source license from www.tendral. com/tsis/
Insect Marks on Bones from La Guillerma Archaeological Locality (Salado River Depression, Buenos Aires, Argentina)

The La Guillerma archaeological locality is located in the northeast sector of Buenos Aires province (Argentina). Two of its sites (LG1 and LG5), dated between ca. 1400- and 600-years BP, have a great amount of faunal remains including deer, rodents, fish and small birds that are subjected to taphonomic agents and processes (e.g., weathering, manganese, roots). Previous studies have shown osteophagic behaviour in different insects (e.g., Coleoptera, Blattodea). In this paper, we evaluate their incidence on La Guillerma faunal assemblage. We performed an analysis on marks that were identified in bone remains of various taxa and applied the criteria for identifying bone alteration by insects (i.e., by measuring each trace and comparing them with the types of insect marks described in the literature). Fifteen specimens (LG1 = 6 and LG5 = 9) exhibited different types of modifications (e.g., pits with striae in base, pits with emanating striae, striations) that are related to the action of insects. Although the proportion of affected bones is low in relation to the total sample, we highlight our study as the first detailed analysis of insect marks on archaeological bones from Argentina. We also emphasize the significance of addressing insect-produced modifications on Argentinean archaeological sites.
Evaluation of different oat (Avena sativa L.) varieties for forage yield and related characteristics

The ample provision of quality fodder is essential for sustainable dairy industry. The development of oat varieties possessing higher forage yield potential will help to produce abundant quantities of fodder for cattle. For this purpose, an experiment was conducted to compare the forage yield of twelve oat (Avena sativa L.) varieties at Agricultural Research Station, Bahawa lpur, Pakistan, during the year 2012-2013. Randomized Complete Block Design was used for the layout of the e xperiment having three replications with plot size of 1.8 m x 6 m. Drill m ethod was used for seed sowing. Data was recorded for plant height, leaf area, tillers per plant, tillers per meter row and green fodder yield. Sgd Oat-2011 was the tallest variety (129.6 cm) while Sgd-4 was the shortest one (82.3 cm). F-411 was found to have a broader leaf area (70.83 cm 2 ) compared to other varieties. F-411 and DN-8 had maximum number of tillers (12 and 11), respecti vely, while varieties Sgd-4, F-403 and Sgd Oat-2011 had least tillers (6). Sgd-3 and No-708 produced highest fodder yield (80 tons ha -1 ) while Hay produced the lowest yield (63.72 tons h a -1 ). Sgd-3 possessed highest number of tillers per meter row ( 211) while variety Colabah had less number of tille rs per meter row (139). From the results, we found that variety Sgd-3 and N o-708 showed better performance than other varieties used in the trial.
Temporal Eating Patterns and Eating Windows among Adults with Overweight or Obesity

We aim to describe temporal eating patterns in a population of adults with overweight or obesity. In this cross-sectional analysis, data were combined from two separate pilot studies during which participants entered the timing of all eating occasions (>0 kcals) for 10–14 days. Data were aggregated to determine total eating occasions, local time of the first and last eating occasions, eating window, eating midpoint, and within-person variability of eating patterns. Eating patterns were compared between sexes, as well as between weekday and weekends. Participants (n = 85) had a median age of 56 ± 19 years, were mostly female (>70%), white (56.5%), and had a BMI of 31.8 ± 8.0 kg/m2. The median eating window was 14 h 04 min [12 h 57 min–15 h 21 min], which was significantly shorter on the weekend compared to weekdays (p < 0.0001). Only 13.1% of participants had an eating window <12 h/d. Additionally, there was greater irregularity with the first eating occasion during the week when compared to the weekend (p = 0.0002). In conclusion, adults with overweight or obesity have prolonged eating windows (>14 h/d). Future trials should examine the contribution of a prolonged eating window on adiposity independent of energy intake.
Effect of Column-Base Flexibility on the Seismic Response and Safety of Steel Moment-Resisting Frames

The effect of column-base flexibility on the response of steel moment frames is assessed through parametric simulation. The response of four frames (2-, 4-, 8-, and 12-story), designed as per current codes, is investigated through static push-over simulations and sophisticated nonlinear response-history simulations, including collapse simulation. For each frame, a range of base fixities is interrogated, including realistic values that are calculated from the designed connections. The results indicate that a reduction in base fixity alters the force distribution and the plastic mechanism, significantly reducing ductility capacity and strength, as well as collapse resilience, while increasing member forces. For the 4-, 8-, and 12-story frames, this trend suggests that the expected response of such frames is worse than is implied by simulations and design approaches that assume a fixed-base condition. However, the trend is beneficial for the 2-story frame, which is analyzed and designed assuming a pinned base.
Comparison of Serum Anti-Mullerian Hormone-Level Changes in Single-Port Laparoscopic Endometriotic and Non-Endometriotic Ovarian Cyst Enucleations

Objectives This study compared serum anti-Mullerian hormone (AMH) levels in endometriotic cysts (ECs) with those in non-ECs and analyzed changes thereof after single-port laparoscopic (SPL) ovarian cyst enucleation using vasopressin injection. Methods In total, 180 patients (EC group, n = 112; non-EC group, n = 68) who underwent SPL ovarian cyst enucleation were retrospectively reviewed. Their AMH levels were checked preoperatively, on postoperative day 10 (POD10), and on postoperative month 3 (POM3). Changes in AMH levels were analyzed according to tumor type and vasopressin use. Results The median initial and postoperative serum AMH levels in the EC group were significantly lower than those in the non-EC group (preoperation: 2.0 vs 3.8 ng/mL, P < 0.001; POD10: 1.0 vs 3.2 ng/mL, P < 0.001; POM3: 1.2 vs 3.6 ng/mL, P < 0.001). The postoperative decrease in AMH levels was higher in the EC group than the non-EC group on POD10 (0.8 vs 0.5 ng/mL, P = 0.011) but not on POM3 (0.7 vs 0.5 ng/mL, P = 0.164). Vasopressin injection during EC enucleation had no significant effect on the decrease in AMH levels on POD10 (vasopressin group vs non-vasopressin group: 1.0 vs 0.8 ng/mL, P = 0.253) and POM3 (vasopressin group vs nonvasopressin group: 1.4 vs 1.1 ng/mL, P = 0.242). Conclusions AMH levels were lower at baseline and had higher decreasing rates after SPL surgery in the EC group relative to the non-EC group. Vasopressin injection might not protect the ovary from the postoperative decrease in AMH levels.
Determination of Novel Anti-Cancer Agents by Targeting OGG1 Enzyme Using Integrated Bioinformatics Methods

The 8-oxoguanine DNA glycosylase (OGG1) enzyme is a key DNA glycosylase mediating the excision of 7,8-dihydro-8-oxoguanine (8-oxoG) from DNA molecule to the start base excision repair pathway. The OGG1 glycosylase function depletion has been seen to obstruct pathological conditions such as inflammation, A3 T-cell lymphoblastic acute leukemia growth, and neurodegenerative diseases, thus warranting OGG1 as an attractive anti-cancer enzyme. Herein, we employed several drug libraries intending to screen non-toxic inhibitory molecules against the active pocket of the enzyme that achieved stable binding mode in dynamics. Two anti-cancer compounds ([O-]C1=C(CC2=CC=CC=C2)SC(=[N+]1CC(=O)NC3=NC=C(CC4=CC=CC=C4)S3)S and CCCN(CCC)[S]-(=O)(=O)C1=CC=C(C=C1)C(=O)NNC2=NC3=CC=C(Br)C=C3C(=N2)C4=CC=CC=C4) from Selleckchem.com were identified to occupy the active pocket of OGG1 and bind with greater affinity than Control TH5487. The binding affinity of Top-1 is −11.6 kcal/mol while that of Top-2 is −10.7 kcal/mol in contrast to TH5487 Control (−9 kcal/mol). During molecular dynamic simulations versus time, the said compounds are tightly held by the enzyme with no minor structural deviations reported except flexible loops in particular those present at the N and C-terminal. Both the compounds produced extensive hydrophobic interactions with the enzyme along with stable hydrogen bonding. The docking and molecular dynamics simulations predictions were further validated by molecular mechanics with generalized Born and surface area solvation (MM/GBSA) and Poisson Boltzmann surface area (MM/PBSA), and WaterSwap binding energies that validated strong binding of the compounds to the enzyme. The MM/GBSA binding free energy for Top-1 complex is −28.10 kcal/mol, Top-2 complex is −50.14 kcal/mol) and Control is −46.91 kcal/mol while MM/PBSA value for Top-1, Top-2 and Control is −23.38 kcal/mol, −35.29 kcal/mol and −38.20 kcal/mol, respectively. Computational pharmacokinetics support good druglike candidacy of the compounds with acceptable profile of pharmacokinetics and very little toxicity. All these findings support the notion that the compounds can be used in experiments to test their anti-cancer activities.
Design of the evaluation model for total ergonomics interventions with fuzzy approach

The present study describes the development of a theory for the guidance of ergonomic interventions (EI) and evaluation processes with the help of fuzzy approach. The study was carried out at an educational center (EC) with the micro- and macro-ergonomic interventions. The combined results of both interventions have demonstrated the positive effects of these techniques in increasing the productivity and reducing the musculoskeletal disorders (MSDs). So, the overall annual performance of the educational center had a significant rise in terms of lower costs, increased revenue and work expansion with less human force . Analysis of questionnaire data "body mapping" with the fuzzy approach has shown that the surrounding surface and fuzzy numbers’ intervals, belonging to the degree of comfort of the qualitative dimensions, were more in the control population as compared to the treatment ones, which indicates that the index of ergonomic interventions is positive in EC.
Differential requirement for the EDS1 catalytic triad in A. thaliana and N. benthamiana

Heterodimeric complexes incorporating the lipase-like proteins EDS1 with PAD4 or SAG101 are central hubs in plant innate immunity. EDS1 functions encompass signal relay from TIR domain-containing intracellular NLR-type immune receptors (TNLs) towards RPW8-type helper NLRs (RNLs) and, in A. thaliana, bolstering of signaling and resistance mediated by cell-surface pattern recognition receptors (PRRs). Biochemical activities underlying these mechanistic frameworks remain unknown. We used CRISPR/Cas-generated mutant lines and agroinfiltration-based complementation assays to interrogate functions of EDS1 complexes in N. benthamiana. We do not detect impaired PRR signaling in N. benthamiana lines deficient in EDS1 complexes or RNLs. Intriguingly, mutations within the catalytic triad of Solanaceae EDS1 can abolish or enhance TNL immunity in N. benthamiana. Furthermore, nuclear EDS1 accumulation is sufficient for N. benthamiana TNL (Roq1) immunity. Reinforcing PRR signaling in Arabidopsis might be a derived function of the TNL/EDS1 immune sector. Dependency of Solanaceae but not A. thaliana EDS1 on catalytic triad residues raises the possibility that a TNL-derived small molecule binds to the Solanaceae EDS1 lipase-like domain, and that EDS1 lipase-like domain pocket contributions to TNL immune responses vary between lineages. Whether and how nuclear EDS1 activity connects to membrane pore-forming RNLs remains unknown.
International Conference on Alternative Energy in Developing Countries and Emerging Economies Electricity generation from a solar parabolic concentrator coupled to a thermoelectric module

The concept of generating electricity from the sun’s energy using a parabolic concentrator and a thermoelectric (TE) module is presented in this study. The proposed TE solar concentrator was composed of a parabolic dish collector with an aperture of 1.5 m that was used to concentrate sunlight onto a receiver plate with an area of 10 × 10 cm. One BiTe-based TE module installed on the receiver plate was used to convert the concentrated solar thermal energy directly into electric energy. A rectangular fin heat sink coupled with a fan was used to release heat from the cold side of TE module and a tracking system was used to continuously track the sun. The effects of fan orientation and air flow rate were investigated. Under maximum heat flux, the TE module was able to produce 1.32 W at 0.42 m/min of the air flow rate (pushing air), corresponding to 2.89% conversion efficiency. The proposed concept seems to be reliable and merits further investigation. © 2013 Published by Elsevier Ltd. Selection and/or peer-review under responsibility of the Research Center in Energy and Environment, Thaksin University.
Microtensiometers Accurately Measure Stem Water Potential in Woody Perennials

Stem water potential (Ψstem) is considered to be the standard measure of plant water status. However, it is measured with the pressure chamber (PC), an equipment that can neither provide continuous information nor be automated, limiting its use. Recent developments of microtensiometers (MT; FloraPulse sensors), which can continuously measure water tension in woody tissue of the trunk of the tree, can potentially highlight the dynamic nature of plant water relations. Thus, this study aimed to validate and assess the usefulness of the MT by comparing the Ψstem provided by MT with those same measurements from the PC. Here, two irrigation treatments (a control and a deficit treatment) were applied in a pear (Pyrus communis L.) orchard in Washington State (USA) to capture the full range of water potentials in this environment. Discrete measurements of leaf gas exchange, canopy temperature and Ψstem measured with PC and MT were made every two hours for four days from dawn to sunset. There were strong linear relationships between the Ψstem-MT and Ψstem-PC (R2 > 0.8) and with vapor pressure deficit (R2 > 0.7). However, Ψstem-MT was more variable and lower than Ψstem-PC when Ψstem-MT was below −1.5 MPa, especially during the evening. Minimum Ψstem-MT occurred later in the afternoon compared to Ψstem-PC. Ψstem showed similar sensitivity and coefficients of variation for both PC and MT acquired data. Overall, the promising results achieved indicated the potential for MT to be used to continuously assess tree water status.
Impact of Capsulectomy Type on Post-Explantation Systemic Symptom Improvement: Findings From the ASERF Systemic Symptoms in Women-Biospecimen Analysis Study: Part 1

Abstract Background Breast Implant Illness (BII) is a term used to describe a variety of symptoms by patients with breast implants for which there are no abnormal physical or laboratory findings to explain their symptoms. There currently exists a difference of opinion among clinicians and patients concerning the diagnosis and treatment of patients self-reporting BII. Objectives The first aim of this study was to determine if there is a valid indication for “en bloc” capsulectomy in patients self-reporting BII and if the type of capsulectomy performed alters long-term symptom improvement. The second goal was to identify any clinical laboratory differences between the cohorts. This study was funded by the Aesthetic Surgery Education and Research Foundation (ASERF). Methods A prospective blinded study enrolled 150 consecutive subjects divided equally into 3 cohorts: (A) women with systemic symptoms they attribute to their implants who requested implant removal; (B) women with breast implants requesting removal or exchange who do not have symptoms they attribute to their implants; and (C) women undergoing cosmetic mastopexy who have never had any implanted medical device. The subject’s baseline demographic data and a systemic symptoms survey, including PROMIS validated questionnaires, was obtained before surgery and at 3-6 weeks, 6 months, and 1 year. Blood was collected from all 3 cohorts and implant capsules were collected from Cohorts A and B. Results 150 patients were enrolled between 2019-2021. Follow-up at 3-6 weeks for all 3 cohorts was between 98%-100%, 78%-98% at 6-months, and 1 year data is currently at 80%. The type of capsulectomy; intact total, total, or partial all showed similar symptom improvement with no statistical difference in the reduction of symptoms based on the type of capsulectomy. Conclusions This study addresses one of the most discussed questions by plastic surgeons, patients, their advocates, and social media. The findings show that patients who self-report BII demonstrate a statistically significant improvement in their symptoms after explantation and that this improvement persists for at least 6 months. This improvement in self-reported systemic symptoms was seen regardless of the type of capsulectomy performed. Level of Evidence: 2
Preschoolers’ use and exploration of concepts related to scientific phenomena in preschool

The study described in this paper concerns science education in preschool, more specifically how young children in preschool settings invent, develop and explore science and scientific concepts in problem-solving and communicative situations. The aim of the paper is to discuss young children´s concept creation and draw conclusions for early science education. The method used was a secondary analysis of empirical material drawn from three previous studies carried out by the authors. Examples of preschool children’s use of language were extracted and was, for the purpose of this study, analyzed with a new focus on children’s use of concepts. The re-analysis draws from Vygotsky’s theoretical framework on children’s conceptual development and appropriation of new concepts (Vygotsky, 1934/1999; Åkerblom 2011) and from the later Wittgenstein (1986) on the role of language meaning in understanding. The findings underline the importance of allowing preschool children to invent, develop and explore science and technology concepts, as well as implications for preschool teachers to create dialogic spaces for the children to do so. The limitations of the study are however that it is based on a limited number of examples and even though it can give implications and point out directions, is not conclusive and should be followed by further research.
Balancing Hydronic Systems in Multifamily Buildings

In multifamily hydronic systems, temperature imbalance may be caused by undersized piping, improperly adjusted balancing valves, inefficient water temperature and flow levels, and owner/occupant interaction with the boilers, distribution and controls. The effects of imbalance include tenant discomfort, higher energy use intensity and inefficient building operation. This paper explores cost-effective distribution upgrades and balancing measures in multifamily hydronic systems, providing a resource to contractors, auditors, and building owners on best practices to improve tenant comfort and lower operating costs. The research was conducted by The Partnership for Advanced Residential Retrofit (PARR) in conjunction with Elevate Energy. The team surveyed existing knowledge on cost-effective retrofits for optimizing distribution in typical multifamily hydronic systems, with the aim of identifying common situations and solutions, and then conducted case studies on two Chicago area buildings with known balancing issues in order to quantify the extent of temperature imbalance. At one of these buildings a booster pump was installed on a loop to an underheated wing of the building. This study found that unit temperature in a multifamily hydronic building can vary as much as 61 degrees F, particularly if windows are opened or tenants use intermittent supplemental heating sources like oven ranges. Average temperaturemore » spread at the building as a result of this retrofit decreased from 22.1 degrees F to 15.5 degrees F. « less
Detection of broken rotor bars in induction motor using starting-current analysis and effects of loading

The detection of broken-rotor-bar faults based on common steady-state-analysis techniques, such as the fast Fourier transform (FFT), is known to be significantly dependent on the loading conditions of the induction motor. At light load, it is difficult to distinguish between healthy and faulty rotors because the characteristic broken-rotor-bar fault frequencies in the stator current are very close to the fundamental-frequency component and their amplitudes are small in comparison. As a result, detection of broken bar faults and classification of the fault severity under light load is very difficult. To overcome this problem, the analysis of the envelope of the transient starting-current waveform using the wavelet-transform has been investigated. The envelope extraction is used to remove the strong fundamental-frequency component, which would otherwise overshadow the characteristic differences between a healthy motor and a faulty motor with broken rotor bars. The wavelet-transform results are processed to develop a normalised parameter called the `wavelet indicator' which is sensitive to the presence of broken-rotor-bar faults. The results are verified using tests on machines with a varying number of broken bars, as well as partially broken rotor bars, over a wide range of loading conditions. The effects of initial rotor position and supply imbalance are also investigated