Miracle-dz/UniFAR-FTUs huggingface dataset:
Transverse Strain of Aponeurosis in Human Tibialis Anterior Muscle at Rest and during Contraction at Different Joint Angles

The aim of the present study was to determine the transverse strain of aponeuroses in human tibialis anterior muscle (TA) in vivo and to clarify the influence of muscle fiber length and state of contraction on the transverse strain. Sagittal and horizontal images of TA were taken in seven men and one woman at ankle angles of –20° (dorsiflexed direction), 0° (neutral anatomic position), and 45° (plantar-flexed direction) both at rest and during submaximal dorsiflexion contraction (20 Nm: 0° and 45°; 10 Nm: –20°) using B-mode ultrasonography. The width of the TA central aponeurosis changed from 21.7 ± 1.0 (mean ± SE) to 25.5 ± 1.1 mm when muscle fiber length changed from 91.0 ± 3.5 (45° in the resting state) to 55.1 ± 3.2 mm (–20° in the active state). The transverse strain of the TA central aponeurosis, which was change in relative width compared with the width at 45° in the resting state, increased when the muscle fiber length decreased. The transverse strain of the TA central aponeurosis was directly pro.
Pregnancy Risk Perception and Associated Factors among Pregnant Women Attending Antenatal Care at Health Centers in Jabi Tehnan District, Amhara, Northwestern Ethiopia, 2021

Background Pregnancy risk perception affects a pregnant woman's decision about health care services such as prenatal care, place of birth, choices about medical interventions, adherence to medical procedures, and recommendations. Therefore, the study is aimed at assessing pregnancy risk perception and associated factors among pregnant women attending antenatal care at health centers in Jabi Tehnan District. Methods An institutional-based cross-sectional study was conducted among 424 mothers attending ANC at health centers in the Jabi Tehnan District from April 1 to 30, 2021. Data was collected through a face-to-face interview using a structured questionnaire which was developed according to the health belief model. The logistic regression model was used using an adjusted odds ratio with 95% CI and pvalue < 0.05 to declare significance and associations. Result Four hundred twenty four (424) pregnant women were interviewed of which nearly half of the respondents 48% (43.2%, 52.7%) had good pregnancy risk perception. Women who had a history of obstetric complications (AOR: 95% CI = 3.44 : 1.73, 6.83), those who knew at least one pregnancy danger sign (AOR: 95% CI = 5.22, 2.46, 11.07), pregnant women who had a bad obstetric history (AOR: 95% CI = 2.23 : 1.13, 4.41), and knowing women who died due to pregnancy-related complications (AOR: 95% CI = 2.85 : 1.45, 5.60) were more likely to have good perception towards pregnancy risk compared to their counterparts. Conclusion Obstetric complications, awareness of pregnancy danger signs, bad obstetric history, and known women who died due to pregnancy-related complications were found to be significantly associated with pregnancy risk perception.
Heating and cooling load frequency distributions implied by monthly building energy use models

Monthly building thermal energy demand calculation procedures such as the utilisation method described in EN ISO 13790 and the monthly degree-day procedure contain parameters that reflect the variation of heating and cooling demands within a particular month. The frequency distribution of the loads is, however, neither explicit nor visible. This frequency information is important when calculating seasonal system efficiency and when apportioning load between the different fuels used in bivalent systems. This paper extracts the distributions embedded in the two procedures and examines the similarities and differences between them. It also illustrates how the distributions vary with the effective thermal capacity of the building. The report proposes appropriate areas of application for these methodologies, bearing in mind the levels of generalisation on which they are based.
The Influence of Age and Oral Health on Taste Perception in Older Adults: A Case-Control Study

Declining gustatory function, nutrition, and oral health are important elements of health in older adults that can affect the aging process. The aim of the present work was to investigate the effect of age and oral status on taste discrimination in two different groups of elderly subjects living either in an Italian residential institution (TG) or in the community (CG). A total of 90 subjects were enrolled in the study (58 CG vs. 32 TG). Masticatory performance (MP) was assessed using the two-color mixing ability test. Taste function was evaluated using cotton pads soaked with six taste stimuli (salty, acid, sweet, bitter, fat and water). A positive correlation between age and missing teeth (r = 0.51, C.I. [0.33; 0.65], p < 0.0001), and a negative correlation between age and MP (r = −0.39, C.I. [−0.56; −0.20], p < 0.001) were found. Moreover, significant differences for salty taste, between TG and CG were detected (p < 0.05). Significant differences in bitter taste sensitivity between subjects wearing removable and non-removable prosthesis were also determined (p < 0.05). In addition, significant gender differences and between males in TG and CG were identified (p < 0.05). The best understanding of the relationship between MP, taste sensitivity, and nutritional factors is a necessary criterion for the development of new therapeutic strategies to address more effectively the problems associated with malnutrition in elderly subjects.
Acute Respiratory Distress Syndrome: Focus on Viral Origin and Role of Pulmonary Lymphatics

Acute respiratory distress syndrome (ARDS) is a serious affection of the lung caused by a variety of pathologies. Great interest is currently focused on ARDS induced by viruses (pandemic influenza and corona viruses). The review describes pulmonary changes in ARDS and specific effects of the pandemic viruses in ARDS, and summarizes treatment options. Because the known pathogenic mechanisms cannot explain all aspects of the syndrome, the contribution of pulmonary lymphatics to the pathology is discussed. Organization and function of lymphatics in a healthy lung and in resorption of pulmonary edema are described. A future clinical trial may provide more insight into the role of hyaluronan in ARDS but the development of promising pharmacological treatments is unlikely because drugs play no important role in lymphedema therapy.
Leveraging the Camino de Santiago: promoting intentional reflection and group cohesion during study abroad

ABSTRACT The present investigation describes how one semester-long study abroad (SA) program leveraged a group excursion at the beginning of the term to promote intentional reflection, a critical skill to process ‘disorienting dilemmas’ often encountered abroad. The excursion took place on the Camino de Santiago, or ‘the Way of Saint James’, a well-known pilgrimage in northern Spain. While multitudes of pilgrims have traveled the Camino for over a millennium, it has rarely been featured in educational research. Eighteen women undergraduates from a US institution participated in a two-day hike on the Camino two weeks into their program, and completed a variety of reflection activities in situ. Data collected immediately after the experience and three months later were analyzed quantitatively and qualitatively. Results suggest that students’ experiences on the Camino – coupled with intentional reflection exercises – helped them gain confidence in the early weeks of their SA semester, and served as a catalyst for camaraderie among participants. Pedagogical and programmatic recommendations of how to structure intentional reflection, especially at the beginning of a SA program, are offered. The article concludes with a call to action to further investigate the role of intensive intentional reflection, especially at the onset of SA.
Estimation of Load Bearing Capacity of Eccentrically Compressed Reinforced Concrete Elements under Dynamic Loading in Fire Conditions

Research of influence of fire impacts on the dynamic strength of eccentrically compressed concrete elements requires a deeper consideration. The purpose of this article is the study of dynamic strength of eccentrically compressed concrete elements in fire conditions under rapidly increasing dynamic loading. It is done the analytical calculation of eccentrically compressed reinforced concrete columns under different thermo powers conditions, there are shown the results of calculations and experimental data. It is shown a graph of dynamic coefficient for concrete depending on the time of dynamic loading and temperature.
Effect of Sulfurization Process on Octahedral Molybdenum Cluster from Mo6 Cluster to MoS2 Nanosheet

The Mo6 cluster which has the great optical properties and chemical activity because of their unique electronic structure have been attracted attention in many fields such as phosphor and photocatalyst. However, the Mo6 cluster it’s hard to recycling which limited its industry application because of its such small nanoscale. Immobilizing the Mo6 cluster on 2-D material has a great value to challenge it. In this research, we study on the sulfurization process of Mo6Br12 cluster to investigate the more possibility of the immobilization of Mo6 cluster.
Prevalence of depression, anxiety and Quality of life among North Indian Polycystic ovary syndrome Women: Evidence from a prospective observational study

Background: Polycystic ovary syndrome (PCOS) is a common heterogeneous gynaecological endocrine disorder characterized by clinical features including oligo-amenorrhea/ovulatory dysfunction, hyperandrogenism and polycystic ovarian morphology. PCOS increases the risk of depression and anxiety which leads to poor quality of life. Aim of the study were to determine the prevalence of anxiety and depression among women suffering from PCOS and to determine the quality of life (QOL) in PCOS women.Methods: The study was prospective, observational, non-interventional and questionnaire-based. 192 women with PCOS voluntarily helped in filling the questionnaires consisting of questions using PHQ-9 for depression, GAD-7 for anxiety, SF-12 for general health and PCOSQ-50 for disease-specific domains. All data were recorded in pre-designed case record forms and analysis of data was done using different statistical methods.Results: Majority of PCOS women were either overweight or obese. Based on PHQ-9 20% of women was suffering with major depression and based on GAD-7, 25% with major anxiety. It is found that psychosocial and emotional domain and coping domain of PCOSQ-50 is significant in patients with major depression and major anxiety. Significant effects were seen on their general health as per SF-12 domain. Lack of physical exercise was found in 83% of women.Conclusions: PCOS is a complex disease which decreases the overall quality of life. Therefore, treatment of PCOS women should include psychological counselling along-with with medication, especially in obese PCOS women. Women should be educated with the benefits of lifestyle modification in PCOS.
Neuronal Intranuclear Inclusion Disease Presenting with Voice Tremor

Neuronal intranuclear inclusion disease (NIID) is an inherited neurodegenerative disease caused by an abnormal GGC repeat expansion of the NOTCH2NCL gene and characterized by eosinophilic hyaline intranuclear inclusions seen in neurons, skin cells, ﬁ broblasts, and skeletal muscle cells. 1,2 Brain magnetic reso-nance imaging (MRI) shows characteristic hyperintense areas in the corticomedullary junction on diffusion-weighted imaging (DWI). Based on the initial and main symptoms, NIID-affected subjects were classi ﬁ ed as dementia-dominant or limb weakness-dominant phenotype. 2 However, an abnormal GGC repeat expansion of the NOTCH2NCL gene has also been reported in hereditary essential tremor-6 (ETM6). 3 ETM6 is characterized by adult-onset kinetic and/or postural tremor in the upper limbs without associated cognitive impairments nor weakness. Skin biopsy shows intranuclear eosinophilic inclusions in the ﬁ bro-blasts and sweat gland cells; their brain MRI also lack characteristic hyperintense areas in the corticomedullary junction on DWI. Therefore, NIID is considered a heterogeneous disorder, and patients may present with an essential tremor before the onset of other symptoms. Here, we report a case of NIID with voice tremor without associated dementia or muscle weakness. A 55-year-old woman with a 2-year of dif ﬁ culty our hospital. The patient ’ s mother was clinically diagnosed with Alzheimer ’ s disease. A strained and strangled voice was observed in the patient. She showed a slight
From Information Overload to Actionable Insights: Digital Solutions for Interpreting Cancer Variants from Genomic Testing

Given the increase in genomic testing in routine clinical use, there is a growing need for digital technology solutions to assist pathologists, oncologists, and researchers in translating variant calls into actionable knowledge to personalize patient management plans. In this article, we discuss the challenges facing molecular geneticists and medical oncologists in working with test results from next-generation sequencing for somatic oncology, and propose key considerations for implementing a decision support software to aid the interpretation of clinically important variants. In addition, we review results from an example decision support software, NAVIFY Mutation Profiler. NAVIFY Mutation Profiler is a cloud-based software that provides curation, annotation, interpretation, and reporting of somatic variants identified by next-generation sequencing. The software reports a tiered classification based on consensus recommendations from AMP, ASCO, CAP, and ACMG. Studies with NAVIFY Mutation Profiler demonstrated that the software provided timely updates and accurate curation, as well as interpretation of variant combinations, demonstrating that decision support tools can help advance implementation of precision oncology.
Antibiotic overuse in obstetric and gynecologic procedures at Zagazig university hospitals: A prospective observational study

Surgical site infection (SSI) constitutes a major problem in healthcare in terms of healthcare cost, morbidity and mortality. Surgical antibiotic prophylaxis (SAP) is one of the effective strategies for SSI prevention. Poor adherence to SAP guidelines across different countries has been observed. Misuse of prophylactic antibiotics threatens patient safety and leads to an increase in the acquisition of antibiotic resistance. The aim of this study was to assess the utilization of SAP in obstetric and gynecologic procedures in terms of indication for prophylaxis, antibiotic selection, timing of administration and prophylaxis duration. A prospective observational study was conducted at the obstetrics and gynecology department of Zagazig University Hospital during the period from January 2020 to June 2020. Medical records of 264 women were recorded and evaluated. The American Society of Health-System Pharmacists (ASHP) therapeutic guidelines, World Health Organization (WHO) recommendations and The American College of Obstetricians and Gynecologists (ACOG) practice bulletin were used for data evaluation and hence women were stratified into two groups. For women who underwent procedures in which guidelines recommended the use of SAP (200 patients; 75.75%), 198 women (99%) received preoperative prophylaxis. None of women (0%) received the recommended first line antibiotic by guidelines while the most commonly used prophylactic antibiotics were Cefotaxime (86 patients; 43.43%) and Ampicillin-sulbactam (62 patients; 31.31%). Preoperative antibiotic prophylaxis timing was 0-60 minutes before skin incision. All women received postoperative prophylaxis that extended to an average of 7 days. Regarding the other group who underwent procedures in which prophylactic antibiotics weren’t recommended by guidelines (64 patients; 24.24%), 37 women (57.81%) followed the guidelines and didn’t receive SAP while 27 women (42.18%) received SAP. Poor adherence to guidelines recommendations regarding prophylactic antibiotic selection and prophylaxis duration was observed. High utilization rate of prophylactic antibiotics in procedures that didn’t require their use was reported.
Do Grittier People Have Greater Subjective Well-Being? A Meta-Analysis

The present study conducted a meta-analysis to examine the relation between grit and subjective well-being (SWB). The association between grit (i.e., overall grit, perseverance of effort, and consistency of interest) and SWB (i.e., positive affect, negative affect, happiness, depression, life satisfaction, job satisfaction, and school satisfaction) were synthesized across 83 studies and 66,518 participants. The results based on a random-effects model showed a substantial correlation between overall grit and SWB (ρ = .46, 95% confidence interval [CI] = [.43, .48]), followed by perseverance of effort (ρ = .38, 95% CI = [.33, .43]) and consistency of interest (ρ = .23, 95% CI = [.17, .28]). The moderator analysis indicated that the correlations between overall grit/consistency of effort and SWB become weaker as age increased, and these links were stronger in affective well-being than in cognitive well-being. Moreover, grit explained unique variance in SWB even after controlling for conscientiousness. Implications and directions for further research are discussed.
General-purpose neural network interatomic potential for the 
α
-iron and hydrogen binary system: Toward atomic-scale understanding of hydrogen embrittlement

To understand the physics of hydrogen embrittlement at the atomic scale, a general-purpose neural network interatomic potential (NNIP) for the α -iron and hydrogen binary system is presented. It is trained using an extensive reference database produced by density functional theory (DFT) calculations. The NNIP can properly describe the interactions of hydrogen with various defects in α -iron, such as vacancies, surfaces, grain boundaries, and dislocations; in addition to the basic properties of α -iron itself, the NNIP also handles the defect properties in α -iron, hydrogen behavior in α -iron, and hydrogen-hydrogen interactions in α -iron and in vacuum, including the hydrogen molecule formation and dissociation at the α -iron surface. These are superb challenges for the existing empirical interatomic potentials, like the embedded-atom method based potentials, for the α -iron and hydrogen binary system. In this study, the NNIP was applied to several key phenomena necessary for understanding hydrogen embrittlement, such as hydrogen charging and discharging to α -iron, hydrogen transportation in defective α -iron, hydrogen trapping and desorption at the defects, and hydrogen-assisted cracking at the grain boundary. Unlike the existing interatomic potentials, the NNIP simulations quantitatively described the atomistic details of hydrogen behavior in the defective α -iron system with DFT accuracy.
EFFICACY OF A MINI-TRAMPOLINE PROGRAM FOR INCREASING THE VERTICAL JUMP

INTRODUCTION Many athletes seek to jump higher. Typical training programs consist of resistive exercises such as plyometrics or weight training. According to Bobbert and Van Soest (1 994), resistive exercises should be combined with or replaced by other exercises, such as repetitive jumping, that develop the technique of jumping. Unfortunately, repetitive jumping may lead to injury from the cumulative trauma of landing. Repetitive jumping on a minitrampoline, however, might circumvent the injury problem and improve the technique of jumping by minimizing forward translation, deep crouching, h d asynchronous coordination. Thus the purpose of this study was to test the efficacy of a repetitive jumping program on the mini-trampoline for improving the vertical jump. Eight female intercollegiate basketball players (age = 20.2 yrs, height = 173.1 cm, mass = 72.1 kg) participated in a jump-training program at the conclusion of their competitive season. Specifically, they performed 12 sets of 5 repetitive jumps on a mini-trampoline twice a week for 5 weeks. Maximal vertical jumps were analyzed before and after the training program. Jump height was measured on a Vertec. Technique was assessed from videotape with a Peak5 Motion Measurement System: Balance was represented by horizontal velocity of the body's center of gravity at takeoff, range of motion was indicated by knee angle at deepest flexion, and coordination was operationalized as the percent of shared positive contribution of the thighs and shanks (SPC). Table of means (f SD) of variables before and after the training program. As a group the subjects significantly increased jump height (p=.02) and reduced forward motion (p=.01). Several individuals reduced knee flexion in the crouch and coordinated their leg segments more simultaneously after the training program. CONCLUSION The mini-trampoline appears to be an effective apparatus for increasing the vertical jump. Also, the minitrampoline seems to elicit better technique from many individuals. REFERENCE Bobbert,. M . J. & Van Soest, A.J. (1994). Effects of muscle strengthening on vertical jump height: A simulation study. M e d w and Science in Sports and Fxercise, 26, 1012- 1020.
Oral Health Status among Migrants from Middle- and Low-Income Countries to Europe: A Systematic Review

Introduction. Economic inequality, political instability and globalization have contributed to the constant growth of the migration phenomenon in recent years. In particular, a total of 4.2 million people migrated to Europe during 2019 and most of them settled in Germany, France and Italy. Objectives. The objective of this study was to conduct a systematic review of studies analyzing the oral health condition among migrants from middle- and low-income countries to Europe and assessing the eventual association between their sociodemographic and socioeconomic characteristics and oral health status. Materials and Methods. A systematic review was conducted in PubMed, Cochrane Library, Scopus and Science Direct databases. After titles, abstracts and full-text examination, only 27 articles were selected on the basis of inclusion criteria and consequently included for quality assessments and data extraction. Results. Most of the studies reported a higher prevalence of caries experience, a poorer periodontal health and more difficulties in accessing dentalcare services among migrant groups compared with the non-migrant population. Inequalities were mostly associated with ethnic background, economic condition and social grade. Conclusion. Our review demonstrates the lack of dental health among migrants, underlining that their cultural beliefs and their social and economic living conditions could influence their oral health.
Microsoft Office 365 on Learning History Subject

<span lang="EN-US">This research aimed at knowing the students' perception of <em>Microsoft Office 365</em> on learning history. This research used a </span><span lang="EN-AU">quantitative descriptive design. It was conducted at SMAN 4 Kendari, Southeast Sulawesi. The sample of this study was students in XI-1 grade. The students were 46. Research instruments used questionnaires and interviews. The result showed that the students had a positive response toward the use of <em>Microsoft Office 365</em>. Besides, 87% of students agree that they can understand History Subject during online learning. The most frequently used features were Teams (95.7%), SharePoint (2.2%), and Forms (2.2%). T</span><span lang="EN-AU">However, the obstacle of using this application is if students do not have facilities such as a good internet network, and laptops. </span>