Miracle-dz/UniFAR-FTUs huggingface dataset:
KAJIAN DESTINASI WISATA HALAL KOTA MEDAN DALAM PERSEPSI PEMASARAN WISATA

Wisata merupakan industri yang paling menjanjikan di masa depan, di mana setiap negara berlomba memperbaiki serta menginvestasikan destinasi wisatanya menjadi lebih baik dan memiliki ciri khas yang dapat dinikmati oleh seluruh wisatawan. Keanekaragaman daerah asal para wisatawan menjadi dasar persepsi, ketika berkunjung ke Kota Medan. Kota Medan adalah ibukota Provinsi Sumatera Utara yang mayoritas penduduknya beragama islam, tetapi kurang mencerminkan suasana islam dalam aktivitasnya. Wisata halal menjadi dasar bagi para wisatawan yang beragama islam untuk berkunjung, paradigma yang muncul dan terbentuk di benak para wisatawan membuat Kota Medan menjadi kota yang kurang ramahakan suasana halal. Penelitian ini bertujuan untuk memperbaiki paragdigma Kota Medan agar menjadi kota yang ramah wisatawan muslim, dengan memberikan strategi pemasaran yang bersifat strategis dan teknis agar dapat dilakukan dengan baik ke depannya. Pada penelitian ini juga ditemukan bahwa faktor-faktor yang mempengaruhi kunjungan ke destinasi wisata adalah; ciri khas, suasana, pengalaman, akomodasi, infrastruktur, transportasi, persepsi, komunikasi, promosi dan keamanan.
Bacterial pattern and antibiotic sensitivity in children and adolescents with infected atopic dermatitis

Atopic dermatitis (AD) is a pruritic and chronic inflammatory skin disease which affected approximately 20% in children. Bacterial infection is common in AD patients and correlates directly with AD severity. A cross-sectional study was conducted to evaluate the prevalence of bacterial skin infection in AD patients and its relation with severity of AD and also to study bacteria in the infected AD and its antibiotic sensitivity. Samples were 86 children and adolescents with an AD in Helvetia Community Health Center Medan from March 2016 until February 2017. Index of SCORing Atopic Dermatitis (SCORAD) was used to evaluate the severity of AD. Lesion and nonlesional skinwere swabbed to take sterile cultures. All bacteria noted and tested for antibiotic sensitivity. Datawere by using Chi-Square and Mann Whitney test with 95% CI and p-value<0.05 was considered statistically significant. Fifty-six AD patients (65.1%) were bacterial infected. There was a significant relationship between severity of AD and bacterial infection (p = 0.006). Staphylococcus aureus was the leading bacteria from all degrees of AD severity. Isolated Staphylococcus aureuswas sensitive to amoxicillin-clavulanate (93.3%), clindamycin (90%), erythromycin (90%), and gentamicin (90%), while sensitivity to tetracycline was low (20%).
Deep 3D Pan via local adaptive "t-shaped" convolutions with global and local adaptive dilations

Recent advances in deep learning have shown promising results in many low-level vision tasks. However, solving the single-image-based view synthesis is still an open problem. In particular, the generation of new images at parallel camera views given a single input image is of great interest, as it enables 3D visualization of the 2D input scenery. We propose a novel network architecture to perform stereoscopic view synthesis at arbitrary camera positions along the X-axis, or Deep 3D Pan, with "t-shaped" adaptive kernels equipped with globally and locally adaptive dilations. Our proposed network architecture, the monster-net, is devised with a novel t-shaped adaptive kernel with globally and locally adaptive dilation, which can efficiently incorporate global camera shift into and handle local 3D geometries of the target image's pixels for the synthesis of naturally looking 3D panned views when a 2-D input image is given. Extensive experiments were performed on the KITTI, CityScapes and our VXXLXX_STEREO indoors dataset to prove the efficacy of our method. Our monster-net significantly outperforms the state-of-the-art method, SOTA, by a large margin in all metrics of RMSE, PSNR, and SSIM. Our proposed monster-net is capable of reconstructing more reliable image structures in synthesized images with coherent geometry. Moreover, the disparity information that can be extracted from the "t-shaped" kernel is much more reliable than that of the SOTA for the unsupervised monocular depth estimation task, confirming the effectiveness of our method.
Identifying Patterns in Complex Field Data: Clustering Heart Rate Responses of Agoraphobic Patients Undertaking Situational Exposure

Ambulatory assessment methods are well suited to examine how patients with panic disorder and agoraphobia (PD/A) undertake situational exposure. But under complex field conditions of a complex treatment protocol, the variability of data can be so high that conventional analytic approaches based on group averages inadequately describe individual variability. To understand how fear responses change throughout exposure, we aimed to demonstrate the incremental value of sorting HR responses (an index of fear) prior to applying averaging procedures. As part of their panic treatment, 85 patients with PD/A completed a total of 233 bus exposure exercises. Heart rate (HR), global positioning system (GPS) location, and self-report data were collected. Patients were randomized to one of two active treatment conditions (standard exposure or fear-augmented exposure) and completed multiple exposures in four consecutive exposure sessions. We used latent class cluster analysis (CA) to cluster heart rate (HR) responses collected at the start of bus exposure exercises (5 min long, centered on bus boarding). Intra-individual patterns of assignment across exposure repetitions were examined to explore the relative influence of individual and situational factors on HR responses. The association between response types and panic disorder symptoms was determined by examining how clusters were related to self-reported anxiety, concordance between HR and self-report measures, and bodily symptom tolerance. These analyses were contrasted with a conventional analysis based on averages across experimental conditions. HR responses were sorted according to form and level criteria and yielded nine clusters, seven of which were interpretable. Cluster assignment was not stable across sessions or treatment condition. Clusters characterized by a low absolute HR level that slowly decayed corresponded with low self-reported anxiety and greater self-rated tolerance of bodily symptoms. Inconsistent individual factors influenced HR responses less than situational factors. Applying clustering can help to extend the conventional analysis of highly variable data collected in the field. We discuss the merits of this approach and reasons for the non-stereotypical pattern of cluster assignment across exposures.
SEED GERMINATION OF Pouteria torta (MART.) RADLK. SUBESP. torta IN DIFFERENT ENVIRONMENTAL CONDITIONS

Germination is considered a critical step in the seedling production process aiming the recovery of environments. Thus, understanding the germination behavior of native species with potential for economic use contributes to the development of the forest seed and seedling chain. Considering the limited information on the tree species Pouteria torta subesp. torta , this study aimed to evaluate its seed germination and formation of normal seedlings using different temperatures and substrates. The experiment was conducted in germination chamber in a research laboratory using two substrates (paper and vermiculite) and six temperatures (20, 25, 30, 35, 20-30 and 25-35 °C) in a completely randomized design in a 2x6 factorial arrangement. Daily evaluation was conducted to verify primary root emission, seed vigor, and seedling formation. The results indicated that the primary root protrusion process began after 20 days of testing under the best conditions, with germination time lasting longer than two months. The results obtained also showed that there was interaction between factors, with use of the vermiculite substrate and the temperatures of 35 and 25-35 °C producing the best germination rates and germination speed index, and use of the paper substrate and the temperatures of 30 and 35 °C showing the best mean germination time. Considering the analyzed variables (germination, germination speed index, and formation of normal seedlings), the temperatures of 35 and 25-35 °C and the vermiculite substrate are the most suitable for the production of Pouteria torta subesp. torta seedlings.
Physical activity in individuals with lower extremity amputations: a narrative review

Background The beneficial effects of physical activity (PA) on the health and well-being of individuals are well established. Physical therapists are often involved in promoting optimal levels of PA in various clinical populations. However, little is known regarding levels of PA or factors associated with PA in individuals with lower extremity (LE) amputations. Objectives To perform a systematic search and synthesize the literature on PA and identify factors associated with PA in individuals with LE amputations. Major findings We systematically reviewed the literature pertaining to PA in adults with a LE amputation. Thirty-five articles from 1995 to 2016 met the inclusion criteria and were included in this narrative review. The majority of participants with LE amputations were found to be sedentary, taking approximately 3000–4000 steps/day. Those with a vascular etiology of amputation or a transfemoral amputation were less active compared to those with a traumatic or transtibial amputation. The manipulation of prosthetic components was often not correlated with changes in PA. Some factors related to PA (i.e. endurance, K-level, use of an assistive device, history of falls) seemed to correlate with PA. Due to a paucity of research, no conclusions were drawn on the physical and mental health benefits of PA in patients with LE amputations or the number of steps/day necessary to optimize health benefits. Conclusions This review reveals the need for continued investigations on PA and the most important factors impacting levels of PA in individuals with LE amputations.
Prevalence of general obesity and central adiposity and its related factors in adult population of Yazd

Introduction: Obesity as one of the most important public health problems is growing worldwide and it is associated with many non-communicable diseases. The aim of this study was investigating the prevalence of general obesity and central obesity and their related factors. Methods: The data of this research were extracted from a population health survey of Yazd province, Iran (YaHS), which was conducted on 9911 adults aged 20-70 years in 2014-2015. Body Mass Index (BMI) < 18.5 was considered underweight, in the range of 18.5 -24.9 healthy, from 25 to 29.9 overweight, and ≥30 was interpreted as obese. Central obesity was defined as the waist circumference (WC) of ≥ 102 cm for men and ≥ 88 cm for women as well as waist to hip ratio (WHO) ≥ 0.90 for men and ≥0.85 for women. Chi-square and one-way ANOVA tests were used for univariate analysis. Results: The prevalence of underweight, overweight, and obesity in both genders were 3.7 % (4.0% in men and 3.4% in women), 37.7% (39.9% in men and 35.6% in women), and 27 % (19.3% in men and 34.7% in women), respectively. The prevalence of abdominal obesity based on WC and WHR were 44.8 (23.9% in males and 65.4% in females) and 69.8% (69.4% in males and 70.2% in females), respectively. Gender (female), old age, being married for both genders, and low education in women were associated with an increase in both types of obesity. Conclusion: Overweight and obesity have population (64%)
Using ranked set sampling with binary outcomes in cluster randomized designs

We study the use of ranked set sampling (RSS) with binary outcomes in cluster‐randomized designs (CRDs), where a generalized linear mixed model (GLMM) is used to model the hierarchical data structure involved. Under the GLMM‐based framework, we propose three different approaches to estimate the treatment effect, including the nonparametric (NP), maximum likelihood (ML) and pseudo likelihood (PL) estimators. We investigate their asymptotic properties and examine their finite‐sample performance via simulation. Based on these three RSS estimators, we further develop procedures for testing the existence of the treatment effect. We examine the power and size of our proposed RSS tests and compare them with existing tests based on simple random sampling (SRS). All the proposed RSS estimation and test methods are illustrated with two data examples, one for rare events and the other for non‐extreme events. Throughout our investigations, we also consider the possible effect of imperfect ranking. Among the proposed methods, we provide recommendations on whether to use RSS rather than SRS with binary outcomes in CRDs and, if yes, when to use which RSS method. The Canadian Journal of Statistics 48: 342–365; 2020 © 2019 Statistical Society of Canada
Strain reduced and photoluminescence enhanced of MoS2 emitters on three-dimensional substrate

Two-dimensional (2D) atomic transition metal dichalcogenides (TMDCs) have distinct emission properties, which can be applied for ultrathin detectors and light-emitters in the future. In this study, strain and photoluminescence of MoS2 monolayer on a 3D substrate through a two-step growth procedure was analyzed. The structural of materials and those optical properties of monolayer TMDCs fabricated on the planar and nonplanar substrate were examined. Monolayer MoS2 grown on the nonplanar substrate exhibited uniform strain reduction and luminescence intensity. The fabrication of monolayer MoS2 on a nonplanar substrate increased the light extraction efficiency. In the future, strain-reduced 2D TMDC materials grown on a nonplanar substrate can be employed as novel light-emitting devices for applications in light-emitters, communication, and displays for ultrathin optoelectronic integrated systems.
STEM Eğitimi Alan Öğretmenlerin eleştirel Düşünme Eğilimlerinin Belirlenmesi

21. yy becerileri arasinda yer alan elestirel dusunme becerisi, gunumuzde dogru bilginin edinilmesi acisindan onemlidir. STEM egitimine ilgi duyan ve bu alanda kendini gelistiren bir ogretmenin elestirel dusunme egilimi de farkli olabilir. Bu baglamda STEM, Arduino veya Robotik egitimi alan 76 ogretmenin; elestirel dusunme egilim duzeylerini belirleme, yas, mesleki deneyim ve cinsiyet acisindan fark olup olmadigini belirlemek amaclanmistir. Arastirma bulgularinda, STEM egitimi alan ogretmenlerin genel olarak orta ustu seviyede elestirel dusunme egilimlerine sahip olduklari, alt boyutlarda alinan puanlarin yuksekten aza dogru Meraklilik, Analitiklik, Acik Fikirlilik, Sistematiklik, Kendine Guven ve Dogruyu Arama seklinde siralandigi soylenebilir. STEM Egitimi alan ogretmenlerin, elestirel dusunme egilimleri yas gruplarina bagli olarak incelendiginde; 31-35 yas gruptakilerin, 22-30 yas gruptakilere gore daha yuksek acik fikirlilige sahip olduklari, meraklilik alt boyutunda ise 36 yas ve ustu gruptakilerin, 31-35 yas ve 22-30 yas gruptakilere gore daha merakli olduklari gorulmustur. Ayrica meraklilik alt boyutunda 36 yas ve ustu ogretmenlerin elestirel dusunme egilimlerinin kendilerinden daha genc olanlara gore yuksek seviyede olmasinin ilgili alanda derinlesmenin etkisi olarak soylenebilir. STEM Egitimi alan ogretmenlerin, elestirel dusunme egilimleri mesleki deneyime bagli olarak incelendiginde; 21 yil ve uzeri grubun, 11-20 yil ve 0-10 yil mesleki deneyime sahip gruplardakilere gore kendilerine daha cok guvendikleri tespit edilmis ve meraklilik boyutunda 21 yil ve ustu mesleki deneyime sahip gruptakilerin, 0-10 yil arasi mesleki deneyime sahip gruptakilere gore daha merakli olduklari gozlenmistir. STEM Egitimi alan ogretmenlerin, elestirel dusunme egilimleri cinsiyete bagli olarak incelendiginde; analitiklik ve kendine guven boyutlarinda farklilik oldugu ortaya cikmis ve erkeklerin lehine oldugu gorulmustur.
Somatic copy number profiling of hepatocellular carcinoma circulating tumor cells.

290Background: Copy number variations (CNVs) have shown prognostic and predictive utility in hepatocellular carcinoma (HCC) but their use from percutaneous biopsies is limited due to HCC’s significant tumor heterogeneity. We investigated the feasibility of obtaining CNV profiles from circulating tumor cells (CTCs) as a liquid biopsy for HCC. Methods: Using a microfluidic HCC-specific CTC assay, CTCs were isolated from 10 patients with HCC and low-resolution (~0.01x) whole genome sequencing performed to establish CNV profiles. Primary tumor, peritumoral liver, and germline DNA was sequenced for comparison. Results: Sequencing of 18 CTC samples (median 4 CTCs/sample) from 10 HCC patients using a low-resolution whole genome sequencing strategy (median 0.88 million reads/sample) revealed frequent copy number changes in previously reported HCC regions such as 8q amplifications and 17p deletions. Analysis of CNV profiles revealed that CTCs share a median of 80% concordance with the primary tumor and that CTCs c.
BRAF in Lung Cancers: Analysis of Patient Cases Reveals Recurrent BRAF Mutations, Fusions, Kinase Duplications, and Concurrent Alterations.

Purpose Dabrafenib and trametinib are approved for the management of advanced non-small-cell lung cancers (NSCLCs) that harbor BRAF V600E mutations. Small series and pan-cancer analyses have identified non-V600 alterations as therapeutic targets. We sought to examine a large genomic data set to comprehensively characterize non-V600 BRAF alterations in lung cancer. Patients and Methods A total of 23,396 patients with lung cancer provided data to assay with comprehensive genomic profiling. Data were reviewed for predicted pathogenic BRAF base substitutions, short insertions and deletions, copy number changes, and rearrangements. Results Adenocarcinomas represented 65% of the occurrences; NSCLC not otherwise specified (NOS), 15%; squamous cell carcinoma, 12%; and small-cell lung carcinoma, 5%. BRAF was altered in 4.5% (1,048 of 23,396) of all tumors; 37.4% (n = 397) were BRAF V600E, 38% were BRAF non-V600E activating mutations, and 18% were BRAF inactivating. Rearrangements were observed at a frequency of 4.3% and consisted of N-terminal deletions (NTDs; 0.75%), kinase domain duplications (KDDs; 0.75%), and BRAF fusions (2.8%). The fusions involved three recurrent fusion partners: ARMC10, DOCK4, and TRIM24. BRAF V600E was associated with co-occurrence of SETD2 alterations, but other BRAF alterations were not and were instead associated with CDKN2A, TP53, and STK11 alterations (P < .05). Potential mechanisms of acquired resistance to BRAF V600E inhibition are demonstrated. Conclusion This series characterized the frequent occurrence (4.4%) of BRAF alterations in lung cancers. Recurrent BRAF alterations in NSCLC adenocarcinoma are comparable to the frequency of other NSCLC oncogenic drivers, such as ALK, and exceed that of ROS1 or RET. This work supports a broad profiling approach in lung cancers and suggests that non-V600E BRAF alterations represent a subgroup of lung cancers in which targeted therapy should be considered.
Predicting poor outcome in patients presenting to primary care with acute cough

Background. Accurate prediction of the course of an acute cough episode could curb antibiotic overprescribing, but is still a major challenge in primary care. Aim. We set out to develop a new prediction rule for poor outcome (re-consultation with new or worsened symptoms or hospital admission) in adults presenting to primary care with acute cough Design and setting. 2604 adults presenting to primary care with acute cough Method. Important signs and symptoms for the new prediction rule were found by combining random forest and logistic regression modelling. Performance to predict poor outcome in acute cough patients was compared to that of existing prediction rules, using the models’ area under the receiver operator characteristic curve (AUC), and improvement obtained by including additional test results (C-reactive protein (CRP), blood urea nitrogen (BUN), chest radiography or etiology) was evaluated using the same methodology. Results. The new prediction rule included the baseline risk of poor outcome, interference with daily activities, number of years stopped smoking (above or below 45 years), severity of sputum, presence of crackles and diastolic blood pressure (above or below 85 mmHg), and severity of sputum. Although performance of the new prediction rule was moderate (sensitivity 62%; specificity 59%; positive predictive value 27%; negative predictive value 86%; AUC 0.62 [0.61-0.67]), it outperformed all existing prediction rules used today (highest AUC 0.53 [0.51-0.56]) and could not be improved by including additional test results (highest AUC 0.64 [0.62-0.68]). Conclusion. The new prediction rule outperforms all existing alternatives in predicting poor outcome in adult patients presenting to primary care with acute cough and could not be improved by including additional test results.
Plasma Flow in the North‐South Aligned Discrete Aurora Equatorward of the Cusp

On the equatorward side of the dayside cusp there often appear diffuse auroras. In this paper, we report north‐south aligned discrete aurora events and show the spatial relationships between the auroras and the plasma flow. Several events of the north‐south aligned discrete auroral structures were identified using an all‐sky imager at Longyearbyen, Svalbard, during the recovery of a moderately disturbed period on 8 December 2013. During a brief interval of the moderately disturbed period, the cusp shifted to higher latitudes; as a result, the field‐aligned beam of the EISCAT Svalbard Radar (ESR) passed through the northern portion of the north‐south aligned auroral structures. Simultaneous observations from the all‐sky imager and ESR reveal that enhancements in ion temperature (caused by fast ion flow) occurred near the eastward and westward boundaries of the north‐south aligned auroral structures. However, within the region of the most enhanced aurora, the ion temperature enhancements were moderately suppressed. These features indicate that the ion flow slows down in the region of electron precipitation responsible for north‐south aligned auroral structures. We can quantitatively interpret the slowdown of the flow as the reduction of the electric field due to the polarization effect in the north‐south aligned region of the increased Pedersen conductivity. It thus appears that the magnetospheric source of the north‐south aligned discrete auroras is a limited area embedded in the region of plasma flow toward the dayside magnetopause.