Miracle-dz/UniFAR-FTUs huggingface dataset:
A The Determinant Factors of Patient Satisfaction among Outpatient and Inpatient Services in A Type B Hospital in Indonesia

Healthcare providers have made various efforts to increase patient and community satisfaction with health services. However, large sample size studies have not been conducted to investigate the determinants of community stratification in Indonesia. This research aimed to analyze determinant factors affecting patient satisfaction in a type B hospital. A cross-sectional with an online survey was used and analyzed with path analysis. A total of 884 participants were recruited with the criteria that all respondents were patients aged 17 years and over who visited the inpatient and outpatient hospital. Overall, the value service satisfaction was very good (scored 87.44 score). Moreover, online service directly increased by age (b = 0.68; 95% CI = 0.08 to 1.27; p = 0.026), gender (b = 0.82; 95% CI = 0.15 up to 1.49; p = 0.016), and education level (b = 1.76; 95% CI = 0.86 to 2.66; p <0.001). Moreover, service costs are directly affected by employment (b = 0.67; 95% CI = 0.92 to 1.26; p = 0.023); and product-specific services were directly affected by age (b = 0.74; 95% CI = 0.20 to 1.29; p = 0.008). These findings suggest that education, gender, and age directly affect online services as an indicator of satisfaction.
Store-and-Forward Teledermatology for Assessing Skin Cancer in 2023: Literature Review

Background The role of teledermatology for skin lesion assessment has been a recent development, particularly, since the COVID-19 pandemic has impacted the ability to assess patients in person. The growing number of studies relating to this area reflects the evolving interest. Objective This literature review aims to analyze the available research on store-and-forward teledermatology for skin lesion assessment. Methods MEDLINE was searched for papers from January 2010 to November 2021. Papers were searched for assessment of time management, effectiveness, and image quality. Results The reported effectiveness of store-and-forward teledermatology for skin lesion assessment produces heterogeneous results likely due to significant procedure variations. Most studies show high accuracy and diagnostic concordance of teledermatology compared to in-person dermatologist assessment and histopathology. This is improved through the use of teledermoscopy. Most literature shows that teledermatology reduces time to advice and definitive treatment compared to outpatient clinic assessment. Conclusions Overall, teledermatology offers a comparable standard of effectiveness to in-person assessment. It can save significant time in expediting advice and management. Image quality and inclusion of dermoscopy have a considerable bearing on the overall effectiveness.
CONSISTENT AND CONSERVATIVE MODEL SELECTION WITH THE ADAPTIVE LASSO IN STATIONARY AND NONSTATIONARY AUTOREGRESSIONS

We show that the adaptive Lasso is oracle efficient in stationary and nonstationary autoregressions. This means that it estimates parameters consistently, selects the correct sparsity pattern, and estimates the coefficients belonging to the relevant variables at the same asymptotic efficiency as if only these had been included in the model from the outset. In particular, this implies that it is able to discriminate between stationary and nonstationary autoregressions and it thereby constitutes an addition to the set of unit root tests. Next, and important in practice, we show that choosing the tuning parameter by Bayesian Information Criterion (BIC) results in consistent model selection. However, it is also shown that the adaptive Lasso has no power against shrinking alternatives of the form c/T if it is tuned to perform consistent model selection. We show that if the adaptive Lasso is tuned to perform conservative model selection it has power even against shrinking alternatives of this form and compare it to the plain Lasso.
The Mechanics of the Circulation

That large area of medical and physiological research which is concerned with the circulation depends, of course, upon many sub-disciplines. Among these, however, an increasingly important role is played by the subject of this book: the mechanics of blood flow, and of blood vessels, and of their interactions. Because the necessary mechanics is relatively refined, it has now become widely accepted that progress in this field will almost always require collaborative work by a team of workers trained in different branches of science: some in the life sciences and some in the mechanical sciences. Several such teams in various parts of the world have been gradually built up so as to work successfully in the field. Hitherto, however, the process of team build-up has been slow because of the lack of texts suitable for facilitating that mutual education of members (each in the others’ disciplines) which is needed if effective communication of ideas based on a certain common background of essential knowledge is to make the collaboration useful. Fortunately, such a text is at last available. Here is a book on the mechanics of the circulation that is equally accessible to those trained in the life sciences and in the mechanical sciences. Furthermore, i t succeeds remarkably in laying down a common foundation of mechanical, anatomical and physiological facts and principles strong enough to support the building-up of major collaborative research structures that can lead to significant new advances in the field. I ts four authors, as might be expected, are of different disciplinary backgrounds (the two doctors of medicine are a physiologist and a physician, while the two doctors of philosophy are a mathematician and an engineer), and have enjoyed an extended period working together in the interdisciplinary Physiological Flow Studies Unit a t Imperial College, London. Every section of the book is the work of more than one of the authors, who have jointly sought to ensure everywhere that no reader, whether grounded in the life sciences or the mechanical sciences, will be a t sea because unfamiliar terminology and ideas are introduced without explanation. Certainly, this is a book which every research worker (with either type of background) concerned with the mechanics of the circulation will wish to possess. Remarkably enough, there is only quite a small portion (just the first five chapters, comprising 15 % of the book) that consists of material which might be assumed familiar to typical readers of the Journal of Fluid Mechanics. Conversely, there is perhaps another 15 yo of the book that might be assumed familiar to readers with a general medical training: just the introductory sections, giving essential anatomical background, to each of the last six chapters (on the blood; the heart; the systemic arteries, microcirculation and veins; and the pulmonary circulation). The remaining 70 yo of the book will lead both types of reader to a common understanding of a wide range of specialized material on the mechanics of the circulation without using any unduly difficult ideas or terminology.
Effect of Anthropometric Parameters on Achilles Tendon Stiffness of Professional Athletes Measured by Shear Wave Elastography

Background: Shear wave elastography (SWE) is currently used to detect tissue pathologies and, in the setting of preventive medicine, may have the potential to reveal structural changes before they lead to functional impairment. Hence, it would be desirable to determine the sensitivity of SWE and to investigate how Achilles tendon stiffness is affected by anthropometric variables and sport-specific locomotion. Methods: To investigate the influence of anthropometric parameters on Achilles tendon stiffness using SWE and examine different types of sports to develop approaches in preventive medicine for professional athletes, standardized SWE of Achilles tendon stiffness was performed in 65 healthy professional athletes (33 female, 32 male) in the longitudinal plane and relaxed tendon position. Descriptive analysis and linear regression were performed. Furthermore, subgroup analysis was performed for different sports (soccer, handball, sprint, volleyball, hammer throw). Results: In the total study population (n = 65), Achilles tendon stiffness was significantly higher in male professional athletes (p < 0.001) than in female professional athletes (10.98 m/s (10.15–11.65) vs. 12.19 m/s (11.25–14.74)). Multiple linear regression for AT stiffness did not reveal a significant impact of age or body mass index (BMI) (p > 0.05). Subgroup analysis for type of sport showed the highest AT stiffness values in sprinters (14.02 m/s (13.50–14.63)). Conclusion: There are significant gender differences in AT stiffness across different types of professional athletes. The highest AT stiffness values were found in sprinters, which needs to be considered when diagnosing tendon pathologies. Future studies are needed to investigate the benefit of pre- and post-season musculoskeletal SWE examinations of professional athletes and a possible benefit of rehabilitation or preventive medicine.
Comprehensive Profiling of Cancer-Associated Cells in the Blood of Breast Cancer Patients Undergoing Neoadjuvant Chemotherapy to Predict Pathological Complete Response

Neoadjuvant chemotherapy (NAC) can affect pathological complete response (pCR) in breast cancers; the resection that follows identifies patients with residual disease who are then offered second-line therapies. Circulating tumor cells (CTCs) and cancer-associated macrophage-like cells (CAMLs) in the blood can be used as potential biomarkers for predicting pCR before resection. CTCs are of epithelial origin that undergo epithelial-to-mesenchymal transition to become more motile and invasive, thereby leading to invasive mesenchymal cells that seed in distant organs, causing metastasis. Additionally, CAMLs in the blood of cancer patients are reported to either engulf or aid the transport of cancer cells to distant organs. To study these rare cancer-associated cells, we conducted a preliminary study where we collected blood from patients treated with NAC after obtaining their written and informed consent. Blood was collected before, during, and after NAC, and Labyrinth microfluidic technology was used to isolate CTCs and CAMLs. Demographic, tumor marker, and treatment response data were collected. Non-parametric tests were used to compare pCR and non-pCR groups. Univariate and multivariate models were used where CTCs and CAMLs were analyzed for predicting pCR. Sixty-three samples from 21 patients were analyzed. The median(IQR) pre-NAC total and mesenchymal CTC count/5 mL was lower in the pCR vs. non-pCR group [1(3.5) vs. 5(5.75); p = 0.096], [0 vs. 2.5(7.5); p = 0.084], respectively. The median(IQR) post-NAC CAML count/5 mL was higher in the pCR vs. non-pCR group [15(6) vs. 6(4.5); p = 0.004]. The pCR group was more likely to have >10 CAMLs post-NAC vs. non-pCR group [7(100%) vs. 3(21.4%); p = 0.001]. In a multivariate logistic regression model predicting pCR, CAML count was positively associated with the log-odds of pCR [OR = 1.49(1.01, 2.18); p = 0.041], while CTCs showed a negative trend [Odds Ratio (OR) = 0.44(0.18, 1.06); p = 0.068]. In conclusion, increased CAMLs in circulation after treatment combined with lowered CTCs was associated with pCR.
Correlation and path analyses in maize (Zea mays L.).

A study was carried out on correlation and path coefficient analysis for eighteen characters on 45 hybrids, 15 inbred lines and 3 testers along with three checks at three locations and in two seasons (kharif 2012 and rabi 2012-13). The traits days to 50 % tasseling, days to 50 % silking, days to maturity, plant height, ear height, ear length, ear girth, number of kernel rows per cob, number kernels per row, starch %, oil %, relative growth rate at 30-60 DAS, net assimilation rate at 30-60 DAS, net assimilation rate at 60-90 DAS, test weight were found to possess significant association in desirable direction with seed yield per plant at both genotypic and phenotypic levels. Path analysis revealed that ear height, ear length, ear girth, net assimilation rate at 30-60 DAS and test weight showed relationship by establishing significant positive direct association with grain yield per plant.
Low-chirp and enhanced-resonant frequency by direct push-pull modulation of DFB lasers

The first long haul experiment on the use of a new direct modulation scheme is reported. This scheme in principle permits simultaneous tailoring of the chirp and enhancement of the resonant frequency of a distributed feedback (DFB) laser. Numerical and analytical results are presented that demonstrate the properties of push-pull modulation along with supporting experiments. Measurement of the time resolved chirp shows that push-pull modulation results in a low-chirp and a unique-chirp shape, which improves pulse transmission along a dispersive fiber. Initial experiments, using a bulk active region unoptimized DFB device driven directly by push-pull modulation, demonstrate operation over 150 km transmission at a bit rate of 2.5 Gb/s with a practical system receiver giving 10/sup -9/ bit-error rate at a dispersion penalty of -0.5 dB. Significant improvements are foreseen using quantum-well material. Simulations indicate that with appropriately optimized devices and drives, direct modulation at 10 Gb/s may give transmission over 100 km of standard fiber comparable to existing externally modulated systems. >
“I didn’t Notice that You Were Watching Me”: Exploring a User Acceptance Study to Conduct Cultural Domain Analysis Online During the COVID-19 Pandemic

This article explores the implementation process of a User Acceptance Study to evaluate the feasibility of conducting cultural domain analysis (CDA) online during the COVID-19 pandemic. We conducted 19 cultural domain analysis sessions involving three techniques: free listing, pile sorts, and rank ordering. A diverse set of participants were recruited to help assess requirements and needs that researching online involves. We found that conducting CDA online is a feasible research method that offers benefits such as generating large amounts of data, making participants feel comfortable joining sessions from a safe space, providing anonymity, reducing research costs such as time and travel, and eliciting large numbers of responses. We also identified several factors for consideration when implementing CDA online and provide recommendations for improvement, including the aesthetics of the digital software employed, user accessibility and digital literacy, participants’ environments, Internet connection, and online-specific ethical issues.
Predicting Workforce Engagement towards Digital Transformation through a Multi-Analytical Approach

The shift towards sustainable and digital practices in organizations is transforming employees’ mindsets and work performance. The digital transformation in academia is leading to meaningful changes in the behaviors and responsibilities of non-academic employees within organizations toward sustainable and responsible practices. By expounding insights into these views through social exchange theory (SET), this study aims to examine the key predictors of employee engagement (EE); namely, knowledge sharing (KS), employee mobility (EM), training and development (TD), and psychological empowerment (PE) in a digital workplace scenario. A quantitative survey based on convenience sampling was conducted to validate the research framework through partial least squares structural equation modelling (PLS-SEM). Accordingly, 205 responses were collected from the non-academic staff of universities in Klang Valley, Malaysia. Data analysis results showed that all hypotheses were significantly accepted. The impact of the model variables on employee engagement in digital transformation was found to be 75%, with employee mobility and knowledge sharing being the most prominent factors. Multigroup analysis (MGA) and importance-performance map analysis (IPMA) were additional analytical tools applied to reinforce the survey findings further and provide more comprehensive insights into employee engagement across different departments within the organization. The findings also showed the robustness of social exchange theory in digital business practices. This research offers novel and innovative perspectives on the impact of various factors (KS, EM, TD, PE) on employee engagement during digital transformation and how they mold employee behavior toward driving productive and responsible outcomes.
Optimizing UAV Resupply Scheduling for Heterogeneous and Persistent Aerial Service

With the current advances in unmanned aerial vehicle (UAV) technologies, aerial vehicles are becoming very attractive for many purposes. However, currently the bottleneck in their adoption is no longer due to architectural and protocol challenges and constraints, but rather to the limited energy that they can rely on. In this article, we design two power resupply schemes under the assumption of a fleet of homogeneous UAVs. Such schemes are designed to minimize the size of the fleet to be devoted to a persistent service (i.e., carried out at all times) of a set of aerial locations. First, we consider the case where the aerial locations to be served are equidistant from an energy supply station. In that scenario, we design a simple scheduling scheme, that we name homogeneous rotating resupply (HoRR), which we prove to be feasible and exact in the sense that it uses the minimum possible number of UAVs to guarantee the permanent coverage of the aerial service locations. Then, we extend that work for the case of nonevenly distributed aerial locations. In this new scenario, we demonstrate that the problem becomes NP-hard, and design a lightweight scheduling scheme, partitioned heterogeneous rotating resupply (PHeRR), which extends the operation of HoRR to the heterogeneous case. Through numerical analysis, we show that PHeRR provides near-exact resupply schedules.
Synchronous variation of dissolved organic carbon in Adirondack lakes at multiple timescales

Dissolved organic carbon (DOC) is a key component of aquatic ecosystems with complex effects on ecosystem function. While long‐term increases in DOC termed “brownification” have received considerable attention, directional trends typically account for a minority of variance. DOC concentrations also fluctuate on seasonal to multiannual timescales, but the causes of such variations are less understood. We used a wavelet‐based approach to study timescale‐specific, spatially synchronous fluctuations in DOC across 49 lakes in the Adirondacks, New York, USA. DOC varies synchronously among lakes at within‐season, annual, and interannual timescales, but relationships with external drivers and internal processes indicated by lake chemistry differed across timescales. External drivers explained 78% of spatial DOC synchrony at the annual time scale. Beyond positive trends related to regional recovery from acidification, variability in DOC is a consequence of fluctuations at several timescales that are common among Adirondack lakes in precipitation, solar radiation, and internal chemical concentrations.
Exploring the Contribution of Curcumin to Cancer Therapy: A Systematic Review of Randomized Controlled Trials

Although the anticancer role of curcumin has been extensively addressed in preclinical research, only a few studies were carried out in humans, with conflicting results. The aim of this systematic review is to collate together the results of the therapeutic effect of curcumin in cancer patients. A literature search was carried out in Pubmed, Scopus, and the Cochrane Central Register of Controlled Trials up to 29 January 2023. Only randomized controlled trials (RCTs) designed to evaluate the effects of curcumin on cancer progression, patient survival, or surgical/histological response were included. Seven out of 114 articles, published between 2016 and 2022, were analyzed. They evaluated patients with locally advanced and/or metastatic prostate, colorectal, and breast cancers, as well as multiple myeloma and oral leucoplakia. Curcumin was given as an add-on therapy in five studies. Cancer response was the most investigated primary endpoint and curcumin issued some positive results. On the contrary, curcumin was ineffective in improving overall or progression-free survival. The curcumin safety profile was favorable. In conclusion, available clinical evidence is not strong enough to support the therapeutic use of curcumin in cancer. New RCTs exploring the effects of different curcumin formulations in early-stage cancers would be welcome.
Digital Platforms and Supply Chain Traceability for Robust Information and Effective Inventory Management: The Mediating Role of Transparency

Background: This article’s main goal is to examine how digital platforms and supply chain traceability (SCT) might contribute to robust information and efficient inventory management (EIM); Methods: SmartPLS3 software was used in conjunction with the partial least squares structural equation modeling (PSL-SEM) technique. Using the snowball sampling method, the software was used to collect data from Pakistani supply chain (SC) specialists; Results: According to this study’s conclusions, robust information and inventory management using digital platforms and SC traceability depend greatly on transparency; Conclusions: Even though investing in digital platforms is a complex process including multiple internal and external parties, this study will be helpful for the decision-makers who make such decisions. The paper identifies research gaps and presents the potential for more research while also increasing awareness of digital platforms, traceability, and transparency in the SC system. There is a shortage of empirical evidence on how digital platforms and SCT lead to robust information and EIM through the mediation association of transparency, notwithstanding the abundance of research conducted on SCT and transparency.
Clinico-Metabolic Profile in Lean Versus Obese Polycystic Ovarian Syndrome Women

Background Polycystic ovarian syndrome (PCOS), which affects women of reproductive age, is the most prevalent endocrine disorder. Signs of excessive androgen, irregular menses, prolonged anovulation, and infertility are characteristics of the clinical phenotype. Women with PCOS are more likely to have diabetes, obesity, dyslipidemia, hypertension, anxiety, and depression. PCOS affects women's health starting before conception and continuing through their post-menopausal years. Methods Ninety-six study subjects were recruited from women visiting the gynaecology clinic according to the Rotterdam criteria for PCOS. Study subjects were then divided into lean and obese groups according to their body mass index (BMI). Demographic data, and obstetrical and gynaecological history were obtained including marital status, menstrual cycle regularity, recent abnormal weight gain (in the preceding six months), and subfertility. To identify any clinical signs of hyperandrogenism such as acne, acanthosis nigricans, or hirsutism, a general and systemic examination was conducted. Data were analyzed after the clinico-metabolic profile was assessed, compared, and contrasted between the two groups. Results The findings showed a significant correlation between obese women with PCOS and the clinical profile of PCOS i.e. menstrual irregularities, acne vulgaris, acanthosis nigricans and hirsutism; the waist-hip ratio was higher in both groups. Higher levels of fasting insulin, fasting glucose: insulin ratio, postprandial sugars, homeostasis model assessment of insulin resistance (HOMA-IR) index, total testosterone, free testosterone, and luteinizing hormone/follicle-stimulating hormone (LH: FSH) ratio were seen in obese women with PCOS, whereas the levels of fasting glucose, serum triglycerides, serum high-density lipoprotein cholesterol (HDL) were higher in all the study subjects irrespective of BMI. Conclusion The study showed that women with PCOS have a deranged metabolic profile like abnormal blood sugar, insulin resistance (IR), and hyperandrogenemia with clinical derangements like irregular menses, subfertility, and recent weight gain more frequently with higher BMI.