Miracle-dz/UniFAR-FTUs huggingface dataset:
Exigências nutricionais, validação de equações para a estimação da composição do corpo vazio e uso da creatinina para estimar a proporção de tecido muscular em bovinos Nelore

The aims of this study were evaluate the intake of dry matter (DMI) and their nutrients, average daily gain (ADG), nutrients digestibility and microbial efficiency and understand the growth development in the EBW and body composition as well as estimate the maturity of Nellore bulls. Thirty seven Nellore bulls were using with initial body weight of 259±24.9 kg and 14 month old. The animals were divided in five to reference group, four to maintenance and the twenty eight animals fed ad libitum were divided in four groups, which each group was slaughter every 42 days. The diet was consisted of corn silage and concentrate (55:45). The power regressions was using for estimate the muscle and bone tissue and the crude protein, mineral matter and water presents in empty body. The exponential model was using for the adipose tissue and ether extract present in empty body. When expressed in kg/day, difference was observed (P<0.05) only to intake of ether extract and neutral detergent fiber in function of feedlot periods. Difference was observed (P<0.05) only to the digestibility coefficient of ether extract. Although there were differences in relation to consumption of nutrients, this difference did not affect the digestibility of the same. The equation by BR CORTE (2010) estimates correctly the dry matter intake of Nellore bulls. The ADG was not influenced (P>0.05) in function of feedlot periods. Differences was not observed (P>0.05) to the microbial efficiency which the average value obtained was 141.50 g of CPmic/kg of TDN. The muscle and bone tissue and the crude protein, mineral matter and water contents in empty body increases when the animal grows, but in smaller proportion. The adipose tissue and the ether extract present in empty body increases the deposition rate when the animal achieves the maturity. The maturity can be estimated considering the moment that the animal achieves 22% of the ether extract in empty body. The Nellore bulls achieve the maturity weight with 455.6 kg of EBW or 497.3 kg of BW. Therefore, this study concluded that the feedlot periods do not influence the intake of dry matter and the some nutrients as well as to the average dairy gain and the
Temporal downscaling of precipitation time-series projections to forecast green roofs future detention performance

Abstract. A strategy to simulate rainfall by the means of different Multiplicative random Cascades (MRC) was developed to evaluate their applicability to produce inputs for green roof infrastructures models taking into account climate change. The MRC reproduce a (multi)fractal distribution of precipitation through an iterative and multiplicative random process. The initial model was improved with a temperature dependency and an additional function to improve its capability to reproduce the temporal structure of rainfall. The structure of the models with depth and temperature dependency was found to be applicable in eight locations studied across Norway (N) and France (F). The resulting time-series from both reference period and projection based on RCP 8.5 were applied to two green roofs (GR) with different properties. The different models lead to a slight change in the performance of GR, but this was not significant compared to the range of outcomes due to ensemble uncertainty in climate modelling and the stochastic uncertainty due to nature of the process. The moderating effect of the green infrastructure was found to decrease in most of the Norwegian cities, especially Bergen (N), while increasing in Lyon (F).
A Sensitive Broadband (UV–vis–NIR) Perovskite Photodetector Using Topological Insulator as Electrodes

Here, a sensitive and broadband perovskite photodetector is developed by using crystalline topological insulator (TI) Bi2Se3 film as the electrode, which is synthesized by molecular beam epitaxy (MBE). The as‐fabricated Bi2Se3‐FA0.85Cs0. 15PbI3‐Bi2Se3 photodetector exhibits apparent sensitivity to 650 nm illumination with an on/off ratio of 0.8 × 105 and good reproducibility. The responsivity, external quantum efficiency, and specific detectivity are estimated to be 8.4 A W−1, 1604%, and 1.7 × 1013 Jones, respectively, which are better not only than the perovskite device using Au as electrode, but also than the majority of other perovskite materials based devices. It is also interesting to find that the TI based perovskite photodetector displays obvious photoresponse to near infrared light (NIR) with 980 nm due to contribution of TI Bi2Se3 layer. It is believed that the present TI based perovskite photodetector holds promise for broadband and high‐performance optoelectronic applications in the future.
Toxic effects of chronic exposure to dyes among workers of synthetic textile industries

Background: textile industry is one of the major industries in Egypt. However, the working environment is associated with potential health hazards. Aim of the work: to study the toxic effects of different types of dyes among workers in textile industries and its effect on their respiratory, renal, and immunological systems. Subjects and methods: this study was conducted on 50 male workers exposed to textile dyeing of different ages, selected from all textile plants with dyeing industry at Borg Al-Arab City compared with 50 males, who were not exposed to textile dye as a control group. Results: both groups were comparable as patient age, while smoking was significantly increased in exposed group (38.0% vs 14.0%). Reported symptoms such as itching, abdominal pain, etc. and respiratory symptoms were significantly increased in exposed group. There was significant increase of AST, ALT, total bilirubin and alkaline phosphatase, urea and serum creatinine in study when compared to control group. Furthermore, there was statistically significant decrease of respiratory function percentage of predicted in study group, and there was statistically significant increase of serum lead concentration in study when compared to the control group (17.18±2.35 vs 6.74±2.29 respectively). In addition, there was significant increase of IgM and IgG in study group. Conclusion: workers in textile industry were significantly exposed to health hazards especially on respiratory system. However, multi-organ affection is the role with increased oxidative stress.
Zinc Chloride Treatment in ATDC5 cells Induces Chondrocyte Maturation

Objectives: Chondrogenesis is an integral part of endochondral ossification during bone healing. Insulin and insulin mimetic compounds like ZnCl2 have been shown to improve bone healing in both normal and diabetic bone healing models. Although the effects of ZnCl2 in processes like osteoblast proliferation and osteoclastogenesis have been evaluated, its role in chondrogenesis is unclear [1-4]. In this study, we determine if ZnCl2 treatment can induce chondrogenic differentiation in the murine chondrogenic ATDC5 cell line in the absence of insulin. Methods: ATDC5 cells were treated with 10ug/ml insulin (IDM), 0µM, 100µM, or 1000µM of ZnCl2 every other day and harvested at the following time points 2hrs, 4hrs, 1d, 2d, 4d, 7d, 10d, 14d, 17d, 21d, 24d, and 28d. ATDC5 chondrogenic differentiation was assayed via Alizarin Red S (ARS) staining, Alcian blue staining, immunoblotting, and QPCR. Results: Our results demonstrate that ZnCl2 treatment can induce proteoglycan and calcium deposition as per Alcian blue and ARS staining in ATDC5 chondrocyte cells. ZnCl2 treatment also increased transcriptional expression of Col2a1 and increased phospho-Akt protein levels over time. Conclusions: The experimental results indicate that ZnCl2 can be promote ATDC5 chondrocytes to differentiate in vitro. Our results coincide with other studies that show that Zn+2 can stimulation collagen production or enhance bone healing outcomes in animal models [4, 5]. Our data indicate that ZnCl2 may be a useful adjuvant for promoting chondrogenesis during endochondral ossification, enhancing cartilage repair, or improving cartilage tissue engineering applications.
A review on invasions by parasites with complex life cycles: the European strain of Echinococcus multilocularis in North America as a model

Abstract Abstract In a fast-changing and globalized world, parasites are moved across continents at an increasing pace. Co-invasion of parasites and their hosts is leading to the emergence of infectious diseases at a global scale, underlining the need for integration of biological invasions and disease ecology research. In this review, the ecological and evolutionary factors influencing the invasion process of parasites with complex life cycles were analysed, using the invasion of the European strain of Echinococcus multilocularis in North America as a model. The aim was to propose an ecological framework for investigating the invasion of parasites that are trophically transmitted through predator–prey interactions, showing how despite the complexity of the cycles and the interactions among multiple hosts, such parasites can overcome multiple barriers and become invasive. Identifying the key ecological processes affecting the success of parasite invasions is an important step for risk assessment and development of management strategies, particularly for parasites with the potential to infect people (i.e. zoonotic).
HUBUNGAN TINGKAT PENGETAHUAN DAN SELF EFFICACY VAKSINASI COVID-19 PADA MAHASISWA FAKULTAS KESEHATAN UNIVERSITAS NURUL JADID

COVID-19 vaccine is the last weapon to reduce morbidity and prevent of death. However, in Indonesia there are many obstacles, the level of knowledge and self-efficacy is very important to note. The purpose of this study was to identify the relationship between the level of knowledge and self-efficacy in Covid-19 vaccination. A correlational study with a cross sectional approach was conducted on the student population of the Faculty of Health, Nurul Jadid University, there were 110 students who participated in this study. The independent variable is Knowledge Level while the dependent variable is Self Efficacy. The instrument in this study used a questionnaire. The results of data analysis with Spearman's rho, obtained a value of r = 0.756 and a value of p = 0.000. Based on the results of the statistical test, it was found that there was a very strong and positive patterned relationship between the level of knowledge and self-efficacy. The conclusion of this study is that there is a significant relationship between the level of knowledge and self-efficacy.
The Mechanism Responsible For Mechanically Enhanced Cancer Cell Invasion

10 Introduction . 11 Methods . 15 Results . 23 Discussion . 39 CHAPTER 3 – THE ROLE OF PAK1 IN THE MATURATION OF INVADOPODIA WITH TRANSIENT MECHANICAL STIMULATION Abstract . 46 Introduction . 47 Methods . 50 Results . 54 Discussion . 63 CHAPTER 4 – THE RESPONSE TO IN VITRO DUAL MECHANOSTIMULATION IS AFFECTED BY A CELL’S METASTATIC CAPACITY Abstract . 66 Introduction . 67 Methods . 68
Effects of Ripening Agent on Nutritional Composition of Two Varieties of Banana (Musa paradisiaca and Musa acuminata)

This study was conducted to make nutritional comparison between natural and artificially ripened banana. Unripe matured banana sample namely T 1 ( Musa paradisiaca ) and T 2 ( Musa acuminata ) were collected in June 2016 from banana orchard at west Khulshi and Jalalabad in Chittagong. These two varieties of banana were divided into two groups. One group was kept control which was naturally ripened and another group was subjected to calcium carbide treatment. Naturally ripened bananas contained dark spots but carbide treated banana had less dark spots on peel and more. Physical appearance of carbide treated banana was more acceptable than a naturally ripened banana. The ripening time of carbide treated Musa paradisiacal (4±0.31 days) and Musa acuminata (6±0.58 days) significantly increased than naturally ripened Musa paradisiacal (8±0.02 days) and Musa acuminata (10±0.50 days). Moisture content increased from 76.65±0.46 to 77.63±0.36 and 66.27±0.15 to 67.96±0.19g/100g respectively in carbide treated banana Musa paradisiaca (T 1 ) and Musa acuminata (T 2 ). In carbide ripened sample T 1 ( Musa paradisiaca ), significantly lower amount of ash, protein and fiber (0.76±0.01 g/100g, 1.77±0.06g/100g, 0.76±0.08g/100g) were observed than naturally ripened (0.84±0.01g/100g, 1.97±0.05g/100g, 1.05±0.23g/100g). In case of T 2 ( Musa acuminata ), ash, carbohydrate, fiber and fat (0.74±0.02g/100g, 25.39±0.14g/100g, 3.78±0.07 g/100g, 0.36±0.01g/100g) were significantly decreased in sample which ripened by carbide than control (0.82±0.01 g/100g, 26.56±0.18 g/100g 4.12±0.07 g/100g,0.41±0.01 g/100g). Vitamin C, sodium and potassium content were decreased but calcium content increased in artificially ripened banana. Artificial ripening agents enhance ripening time and provides a acceptable physical appearance but reduces nutritional composition of banana.
İskenderun Körfezi Deniz Suyunun Eser Element Düzeylerinin Araştırılması

Bu calismada Iskenderun Korfezi deniz suyu eser element yonunden arastirilarak bu elementlerin belirli periyotlarla degisimleri incelenmistir. Kirlilik olcumleri icin dort ayri istasyon belirlenmistir. Kasim 2014 ve Mart 2015 tarihleri arasinda bes ay boyunca 15 gunluk periyotlarla 40 adet deniz suyu numunesi toplanmistir. Bu numunelerin pH, iletkenlik degerleri ile bor, aluminyum, krom, demir, nikel, bakir, arsenik ve selenyum (B, Al, Cr, Fe, Ni, Cu, As ve Se) konsantrasyonlari olculmustur. Ortalama pH degeri 8,04 olarak belirlenmistir. Ortalama iletkenlik degeri 103430 µS/cm olarak belirlenmistir. Eser element analizi ICP-MS cihazi ile yapilmistir. Ortalama eser element konsantrasyonlari; B: 6,559; Al: 0,666; Cr: 0,243; Fe: 7,142; Ni: 0,094; Cu: 0,364; As: 0,055 ve Se: 0,275 ppm olarak bulunmustur. Analiz sonuclarina bakildiginda B, Al, Cr, Fe, Cu ve Se elementlerinin konsantrasyonlarinin sinir degerlerin uzerinde oldugu bulunmustur. Ni ve As elementlerinin konsantrasyonlarinin sinir degerlerin altinda oldugu bulunmustur.
Addressing ethical and laboratory challenges for initiation of a rapid whole genome sequencing program

Abstract Rapid whole genome sequencing (rapid WGS) is a powerful diagnostic tool that is becoming increasingly practical for widespread clinical use. However, protocols for its use are challenging to implement. A significant obstacle to clinical adoption is that laboratory certification requires an initial research development phase, which is constrained by regulations from returning results. Regulations preventing return of results have ethical implications in cases which might impact patient outcomes. Here, we describe our experience with the development of a rapid WGS research protocol, that balanced the requirements for laboratory-validated test development with the ethical needs of clinically relevant return of results.
Exploring the effects of the quaternary glacial–interglacial cycles on the geographic distributions of tropical Andean rodents: species in the genus Aepeomys Thomas, 1898 (Thomasomyini: Sigmodontinae: Cricetidae) as a case study

ABSTRACT The Quaternary glaciations had great impacts on the historical biogeography of small mammal species. Recent studies have showed the effects of these climatic cycles on the diversification of several Neotropical rodents, but these have focused on species whose distributions do not encompass the tropical Andes. Thus, the influences of these climatic dynamics on the evolutionary history of tropical Andean rodent species remain unknown. The effects of these climatic changes were addressed on Aepeomys lugens and A. reigi, two Thomasomyine endemics from the Cordillera de Mérida in the Venezuelan Andes. The past potential geographic distribution of both species was inferred using an ecological niche modeling approach. The estimations obtained indicated that the availability of the suitable climatic conditions for these taxa has varied in size and location during the last 140,000 years. The spatial projection of the niche models onto the climatic scenarios explored indicates that the effects over the historical distributions were smaller in A. lugens than in A. reigi. These results show that the current geographic distribution of both Andean rodents conceals complex biogeographic histories, and characterizations of the demographic history and genetic diversity will be required to understand the evolution of the genus Aepeomys in the Andes.
Mean and variance of Brownian motion with given final value, maximum and argmax

Abstract The conditional expectation and conditional variance of Brownian motion, B(t), is considered given B(t = 1), its maximum and its argmax, as well as those with less information: where the close is the final value: and We compute the expectation and variance of a Brownian meander in time. By splicing together two Brownian meanders, the mean and variance of the constrained process are calculated. Analytic expressions are given for and as well as the analogous expression for the conditional variance. Computational results displaying both the expectation and variance in time are presented. Comparison of the simulation with theoretical values are shown when the close and argmax are given. We show that using the values of and as well as the final value, c, significantly reduces the variance of the process compared to the variance of the Brownian bridge.
Intracellularly selected recombinant antibodies targeting β Amyloid Oligomers

5 Introduction 1. Alzheimer’s Disease and Beta Amyolid peptide 9 1.1 Alzheimer’s Disease: a Protein Misfolding Disorder 9 1.2 Beta Amyloid in Alzheimer’s Disease 10 1.3 Aβ generation: the processing of Amyloid Precursor Protein (APP) 11 1.4 Interactions between the cholinergic system, neurotrophins and APP metabolism 14 1.5 Aβ aggregation 15 1.6 Aβ oligomers 18 1.7 Soluble oligomers in AD pathogenesis 19 1.8 Intracellular oligomerization 21 2. Targeting Beta Amyloid through antibodies 22 2.1 Targeting Aβ pathological assemblies through antibodies: from in vitro studies to in vivo applications 22 2.2 Immunotherapy 24 3. From recombinant antibodies to their in vivo intracellular selection 27 3.1 Recombinant antibodies 27 3.2 From the principle of intracellular antibodies to the development of new strategies of antibody selection 30 3.3 IACT and SPLINT: novel approaches to select recombinant antibodies targeting Aβ oligomers 37
Decomposing the Effect of Brand Image in Influencing Information Adoption: The Case of Online Travel Agents

The availability of information in the form of online reviews offered by online travel agents (OTAs) is playing an important role in the travel decisions of today’s consumer. Considering the huge amount of attention given to behavioral dimension in decision making literature and the popularity of the information adoption model, the present study aims at exploring the direct and indirect effect of information quality (IQ) and information credibility (IC) on attitude toward information usefulness (AT). The study specifically bridges the gap in the literature of information adoption by using brand image (BI) of the OTA as a mediator. The research also examines the subsequent effect of attitude toward information usefulness on information adoption (IA). Convenience sampling technique has been used to gather responses and structural equation modeling has been used to analyze the data. The results confirm the presence of partial mediation effect in the proposed relationships between IQ, IC, BI, and AT and posit a significant effect of attitude toward information usefulness on the adoption of information. The study concludes that it is imperative for marketers in the travel industry to understand that perception of their brand plays a very important role in positioning their information as a useful one.
Development of AI-Based Vehicle Detection and Tracking System for C-ITS Application

There are various means of monitoring traffic situations on roads. Due to the rise of artificial intelligence (AI) based image processing technology, there is a growing interest in developing traffic monitoring systems using camera vision data. This study provides a method for deriving traffic information using a camera installed at an intersection to improve the monitoring system for roads. The method uses a deep-learning-based approach (YOLOv4) for image processing for vehicle detection and vehicle type classification. Lane-by-lane vehicle trajectories are estimated by matching the detected vehicle locations with the high-definition map (HD map). Based on the estimated vehicle trajectories, the traffic volumes of each lane-by-lane traveling direction and queue lengths of each lane are estimated. The performance of the proposed method was tested with thousands of samples according to five different evaluation criteria: vehicle detection rate, vehicle type classification, trajectory prediction, traffic volume estimation, and queue length estimation. The results show a 99% vehicle detection performance with less than 20% errors in classifying vehicle types and estimating the lane-by-lane travel volume, which is reasonable. Hence, the method proposed in this study shows the feasibility of collecting detailed traffic information using a camera installed at an intersection. The approach of combining AI and HD map techniques is the main contribution of this study, which shows a high chance of improving current traffic monitoring systems.
Holocene glacier history of northeastern Cordillera Darwin, southernmost South America (55°S)

Abstract In the Cordillera Darwin, southernmost South America, we used 10Be and 14C dating, dendrochronology, and historical observations to reconstruct the glacial history of the Dalla Vedova valley from deglacial time to the present. After deglacial recession into northeastern Darwin and Dalla Vedova, by ~16 ka, evidence indicates a glacial advance at ~13 ka coeval with the Antarctic Cold Reversal. The next robustly dated glacial expansion occurred at 870 ± 60 calendar yr ago (approximately AD 1150), followed by less-extensive dendrochronologically constrained advances from shortly before AD 1836 to the mid-twentieth century. Our record is consistent with most studies within the Cordillera Darwin that show that the Holocene glacial maximum occurred during the last millennium. This pattern contrasts with the extensive early- and mid-Holocene glacier expansions farther north in Patagonia; furthermore, an advance at 870 ± 60 yr ago may suggest out-of-phase glacial advances occurred within the Cordillera Darwin relative to Patagonia. We speculate that a southward shift of westerlies and associated climate regimes toward the southernmost tip of the continent, about 900–800 yr ago, provides a mechanism by which some glaciers advanced in the Cordillera Darwin during what is generally considered a warm and dry period to the north in Patagonia.