Miracle-dz/UniFAR-FTUs huggingface dataset:
Element fluxes associated with subduction related magmatism

Destructive plate margin magmas may be subdivided into two groups on the basis of their rare earth element (REE) ratios. Most island arc suites have low Ce/Yb, and remarkably restricted isotope ratios of 87Sr/86Sr = 0.7033, 143Nd/144Nd = 0.51302, 206Pb/204Pb = 18.76 , 207Pb/204Pb = 15.57, and 208Pb/204Pb = 38.4. However, they also have Rb/Sr (0.03), Th/U (2.2) and Ce/Yb (8.5) ratios which are significantly less than accepted estimates for the bulk continental crust. The high Ce/Yb suites have higher incompatible element contents, more restricted heavy REE, and much more variable isotope ratios. Such rocks are found in the Aeolian Islands, Grenada, Indonesia and Philippines, and their isotope and trace element features have been attributed both to contributions from subducted sediment, and/or old trace element enriched material in the mantle wedge. It is argued that for isotope and trace element models the slab component can usefully be taken to consist of subducted sediment and altered mid-ocean ridge basalts, since these may contain ca. 80% of the water in the subducted slab, and the distinctive trace element features of arc magmas are generally attributed to the movement of material in hydrous fluids. The isotope data indicate that not more than 15% of the Sr and Th in an average arc magma were derived from subducted material, and that the rest were derived from the mantle wedge. The fluxes of elements which cannot be characterized isotopically are more difficult to constrain, but for most minor and trace elements the slab derived contribution in arc magmas is too small to have a noticeable effect on the residual slab.
Real Time Contingency Measures to Cope with Rainfall Variability in Southern Karnataka

Real time contingency practices viz., selection of varieties, date of sowing, method of crop establishment, soil and moisture conservation practices were demonstrated in the Chikkamaranahalli cluster villages, Bengaluru rural district of Karnataka during 2011 to 2014. Selection of long duration variety (MR-1) for July sowing, medium duration (GPU-28) for August 1st fortnight and short duration (GPU-48) for August 2nd fort night performed better. In-situ conservation moisture through opening of conservation furrow between paired rows of pigeonpea under finger millet + pigeonpea (8: 2) and groundnut + pigeonpea (8: 2) recorded significantly higher yields (2749 kg/ha and 1347 kg/ha, respectively) compared to farmers’ practice. Among different methods of establishment in finger millet, transplanting recorded significantly higher grain yield (2461 kg/ha) and sowing of finger millet using modified bullock drawn seed drill recorded significantly higher yield (2417 kg/ha) compared to conventional method of broadcasting.
Dovepress individualized treatment of chronic hepatitis C with pegylated interferon and

odalgard@medisin.uio. no Abstract: Chronic infection with hepatitis C virus (HCV) is a major public health problem, with perhaps 180 million people infected worldwide. A significant proportion of these will eventually develop clinical complications, such as cirrhosis, liver decompensation and hepatocellular carcinoma. Sustained virological response (SVR) to antiviral therapy is associated with improvement in liver histology and survival free of liver-related complications. Great effort has been made to improve SVR rate by adapting the duration of therapy according to HCV genotype and to on-treatment response. Rapid virological response (RVR, undetectable HCV RNA at week 4) usually has a high positive predictive value for achieving SVR and early virological response (EVR,  2 log reduction or undetectable HCV RNA at week 12) exhibits a high negative predictive value for non-response. Individualized approach can improve cost-effectiveness of HCV antiviral therapy by reducing side effects and the costs of therapy associated with unnecessary exposure to treatment and through extending therapy for those with unfavorable features. This article summarizes recent data on strategies of individualized treatment in naïve patients with mono-infection by the different HCV genotypes. The management of common side effects, the impact of HCV infection health-related quality of life and the potential applications of host genomics in HCV therapy are also
DESIGN TOOLS FOR PIEZOELECTRIC ACTUATED INCHWORM POSITIONERS

Several piezoactuated inchworm motors are being developed for ultraprecision applications. Performance of the motor depends on the interaction of the frame stiffness and piezoelectric properties. In an effort to develop optimum designs, a set of design equations were derived from standardized kinematic models. They facilitate quick iteration and convergence to an acceptable design based on the requirements. The accuracy of the equations was assessed by comparing them to several finite element analyses. Future research will include prototype tests to validate both the analytical and finite element models. 6 th CanSmart Workshop
Power control of VSC HVDC converters for limiting the influence of AC unbalanced faults on multi-terminal DC grids

It will be important for the operation of future multi-terminal HVDC systems that each converter unit is capable of limiting the influence of nearby AC faults on the DC grid. Thus, the local control systems at each terminal should be able to prevent double frequency active power oscillations caused by unbalanced AC faults from propagating to the DC-side of the converter. A simple approach for achieving this objective, while ensuring that the converter currents are limited to safe values, is therefore presented in this paper. The proposed method is based on estimation of Positive and Negative Sequence Virtual Flux components at the terminals of the converter. Double frequency oscillations in the active power flow through the converter can therefore be eliminated during unbalanced conditions, without considering the influence of the filter inductors. By preventing power oscillations in the DC system, while keeping the currents within the available rating, the proposed control system will prevent converter tripping and unwanted interruption of system operation. (7 pages)
Subendothelial Foci of Infectious Leukocytes Leukocytes and the Development of Transendothelial Migration of HIV-Infected Impact of Fibronectin Fragments on the

Leukocyte inﬁltrates that can serve as viral reservoirs, and sites for viral replication are found in many organs of HIV-1-infected patients. Patients whose blood leukocytes migrate across conﬂuent endothelial monolayers ex vivo and transmit infectious virus to mononuclear leukocytes (MNLs) lodged beneath this endothelial barrier have a worse prognosis. We evaluated the ability of 110- to 120-kDa ﬁbronectin fragments (FNf), which are found in the blood of > 60% of HIV-1-infected patients, to stimulate transendothelial migration and drive productively infected MNLs into a potential perivascular space. FNf induced MNLs to release TNF- (cid:1) in a dose-dependent fashion; the resulting increase in lymphocyte and monocyte transendothelial migration could be blocked with soluble TNF receptor I. Rather than penetrate deeply into the subendothelial matrix, as is seen with untreated controls, FNf-treated MNLs clustered just below the endothelial monolayer. Treatment with FNf during migration increased subsequent recovery of HIV-infected cells from the subendothelial compartment. FNf treatment also signiﬁcantly increased the numbers of HLA-DR bright , dendritic-type cells that reverse-migrated from the subendothelial depot to the apical endothelial surface 48 h after migration. Fibronectin fragments can be produced by viral and host proteases in the course of inﬂammatory conditions. The ability of FNf to stimulate transendothelial migration of HIV-1-infected MNLs may help to explain the dissemination of this infection into cardiac, renal, and CNS tissues. The Journal of Immunology, 2004, 173: 2746–2754. Flow-Set ﬂuorospheres (Beckman Coulter) to remove variability attribut- able to day-to-day ﬂuctuations in instrument performance. mAbs (Beck-man Coulter) included anti-CD14 (clone M5E2), anti-CD11b (CR3, clone Bear1), CD49d (clone HP2/1), CD49e (clone Sam1), CD62L (clone DREG 56), CD45 (clone J.33), CD4 (clone SFCI12T4D11), and CD8 (clone used from CA). of data performed
Change in stroke presentations during COVID-19 pandemic in South-Western Sydney.

Background: Australia managed relatively well during the global COVID-19 pandemic owing to our swift mandated public health response. During the NSW lockdown restrictions, we noted a decrease in acute stroke presentations at our institution, similar to what was subsequently reported worldwide. Aims: We aimed to test our hypothesis that (i) the true numbers of ischaemic strokes did not change, however patients were presenting later and (ii) the proportion of TIAs decreased. Methods: We conducted a retrospective audit of all stroke and TIA presentations in 2020 and compared these with data from 2019. We collected information about stroke subtype, severity, time from stroke/TIA onset to presentation and acute reperfusion therapies. Results: Between January-February and April-March 2020, there was a 15% drop in acute stroke presentations (128 vs. 109). In the same period "stroke mimic" presentations dropped by 22%. The proportion of patients attending the emergency department within 4.5hrs was only 36% compared with 48% over the similar period in 2019. Conclusions: Although the raw numbers of ischemic stroke presentations remained stable during NSW Covid lockdown, the proportion of patients presenting within time window for acute reperfusion therapies fell. The number of TIAs similarly fell suggesting COVID-19 discouraged patients from presenting to hospital which placed them at higher risk of disabling stroke. The opportunity cost of lockdown restrictions on stroke outcome should be considered in future policy directives.
Childhood Stunting and Its Associated Factors in Ethiopia

Child stunting is most prevalent in Amhara, Benishangul-Gumuz, Afar, and Dire Dawa (41-46 percent), whilst wasting is most prevalent in Somali (23 percent), Afar (18 percent), and Gambella (14 percent) (14 percent). Drought-related public health and nutrition difficulties were reported in hard-to-reach districts of Afar, Somalia, Benishangul-Gumuz, and Gambella. The majority of Ethiopian research that have used EDHS data have looked at factors that contribute to childhood stunting while ignoring the proper sampling strategy and clustered structure of the EDHS data. Thus, this study intends to close this gap by using cluster specific models from a variety of statistical models to identify risk variables for childhood stunting among Ethiopian children under the age of five.
Title: Optimal thromboprophylaxis strategies in non-critically ill patients with COVID-19 pneumonia. The PROTHROMCOVID Randomized Controlled Trial. Running Title: Thromboprophylaxis in COVID-19 pneumonia: The PROTHROMCOVID

Authors: Nuria Muñoz-Rivas1,Jesús Aibar2, Cristina Gabara-Xancó2,Ángela TruebaVicente3, Ana Urbelz-Pérez3, Vicente Gómez-Del Olmo4 Pablo Demelo-Rodriguez 5. Alberto Rivera-Gallego6,Pau Bosch-Nicolau7 Montserrat Perez-Pinar8 Mónica RiosPrego9. Olga Madridano-Cobo10. Laura Ramos-Alonso11. Jesús Alonso-Carrillo12. Iria Francisco-Albelsa13 Edelmira Martí-Saez14. Ana Maestre-Peiró 15 Manuel MéndezBailón16 José Ángel Hernández-Rivas17, Juan Torres-Macho18 on behalf of The PROTHROMCOVID Trial investigators.
Microgrid protection using Hilbert–Huang transform based-differential scheme

Time-frequency-based differential scheme is proposed for microgrid protection using non-stationary signal analysis. The non-stationary signal processing algorithm Hilbert-Huang Transform (HHT) have been implemented for the protection objective and the comparative assessment with that of S-transform, differential current is carried out in order to demonstrate the reliability of the proposed protection scheme with different case studies. The series of simulation results demonstrates the efficacy of HHT, than that of S-transform in some critical cases such as high impedance fault where accurate detection is a challenge. The configuration of the microgrid test model has been developed in PSCAD with different distributed generation such as photovoltaic and wind generation system penetrated at different buses. Thus, it is found that the HHT scheme is quite reliable and efficient for fault detection objective.
The integral membrane protein, ponticulin, acts as a monomer in The integral membrane protein, ponticulin, acts as a monomer in nucleating actin assembly nucleating actin assembly us how benefits you.

Ponticulin, an F-actin binding transmembrane glycoprotein in Dictyostelium plasma membranes, was isolated by detergent extraction from cytoskeletons and purified to homogeneity. Ponticulin is an abundant membrane protein, averaging 'x,106 copies/ cell, with an estimated surface density of ,,o 300 per #m 2. Ponticulin solubilized in octylglucoside exhibited hydrodynamic properties consistent with a ponticulin monomer in a spherical or slightly ellipsoidal detergent micelle with a total molecular mass of 56 + 6 kD. Purified ponticulin nucleated actin polymerization when reconstituted into Dictyostelium lipid vesicles, but not when a number of commercially available lipids and lipid mixtures were substituted for the endogenous lipid. The specific activity was consistent with that expected for a protein comprising 0.7 + 0.4 %, by mass, of the plasma membrane protein. Ponticulin in octylglucoside micelles bound F-actin but did not nucleate actin assembly. Thus, ponticulin-mediated nucleation activity was sensitive to the lipid environment, a result frequently observed with transmembrane proteins. At most concentrations of Dictyostelium lipid, nucleation activity increased linearly with increasing amounts of ponticulin, suggesting that the nucleating species is a ponticulin monomer. Consistent with previous observations of lateral interactions between actin filaments and Dictyostelium plasma membranes, both ends of ponticulin-nucleated actin filaments appeared to be free for monomer assembly and disassembly. Our results indicate that ponticulin is a major membrane protein in Dictyostelium and that, in the proper lipid matrix, it is sufficient for lateral nucleation of actin assembly. To date, ponticulin is the only integral membrane protein known to directly nucleate actin
Measuring Urban Design Metrics For Livable Places

Thank you very much for downloading measuring urban design metrics for livable places. Maybe you have knowledge that, people have look hundreds times for their favorite novels like this measuring urban design metrics for livable places, but end up in infectious downloads. Rather than enjoying a good book with a cup of tea in the afternoon, instead they cope with some malicious virus inside their desktop computer.
POST KEYNESIANISM MEETS FEMINIST ECONOMICS 1

This article explores the relationships between Post Keynesian economics and feminist economics. It distinguishes three key concepts in each tradition that recommend serious attention in the other tradition: gender, the household, and unpaid work and caring as key concepts in feminist economics, and uncertainty, market power and endogenous dynamics as core concepts in Post Keynesian economics. The paper will show, with reference to the literature in which such cross-fertilization already has been explored, how both traditions can be enriched from a stronger mutual engagement.
An Implementation of Galactic White Dwarf Binary Data Analysis for MLDC-3.1

The space-borne gravitational wave detectors will observe a large population of double white dwarf binaries in the Milky Way. However, the search for double white dwarfs in the gravitational wave data will be time-consuming due to the large number of templates involved and antenna response calculation. In this paper, we implement an iterative combinatorial algorithm to search for double white dwarfs in MLDC-3.1 data. To quickly determine the rough parameters of the target sources, the following algorithms are adopted in a coarse search process: (1) using the downsampling method to reduce the number of original data points; (2) using the undersampling method to speed up the generation of a single waveform template; (3) using the stochastic template bank method to quickly construct the waveform template bank while achieving high coverage of the parameter space; (4) combining the FFT acceleration algorithm with the stochastic template bank to reduce the calculation time of a single template. A fine search process is applied to further determine the parameters of the signals based on the coarse search, for which we adopt the particle swarm optimization. Finally, we detect (104) double white dwarf signals, validating the feasibility of our method.
Learning to Solve Vehicle Routing Problems: A Survey

This paper provides a systematic overview of machine learning methods applied to solve NP-hard Vehicle Routing Problems (VRPs). Recently, there has been a great interest from both machine learning and operations research communities to solve VRPs either by pure learning methods or by combining them with the traditional hand-crafted heuristics. We present the taxonomy of the studies for learning paradigms, solution structures, underlying models, and algorithms. We present in detail the results of the state-of-the-art methods demonstrating their competitiveness with the traditional methods. The paper outlines the future research directions to incorporate learning-based solutions to overcome the challenges of modern transportation systems.
The Dark Matter Tidal Stripping History of the Sagittarius Core with N-body Simulations

The infall of the Sagittarius (Sgr) dwarf spheroidal galaxy in the Milky Way halo is an unique opportunity to understand how the different components of a dwarf galaxy could be tidally removed. In this work, we reconstruct the Sgr core morphology and kinematics on the basis of a model that has already successfully reproduced the Sgr stream. Here we use a very high resolution model that almost resolves individual stars in the Sgr core. It reproduces most of the observed morphology and kinematic properties, without specific fine tuning. We also show that the dark matter may have been almost entirely stripped by Milky Way tides after two passages at the pericenter. Finally the model predicts that the Sgr core will be fully disrupted within the next 2 Gyr.
Efficient yet Competitive Speech Translation: FBK@IWSLT2022

The primary goal of this FBK’s systems submission to the IWSLT 2022 offline and simultaneous speech translation tasks is to reduce model training costs without sacrificing translation quality. As such, we first question the need of ASR pre-training, showing that it is not essential to achieve competitive results. Second, we focus on data filtering, showing that a simple method that looks at the ratio between source and target characters yields a quality improvement of 1 BLEU. Third, we compare different methods to reduce the detrimental effect of the audio segmentation mismatch between training data manually segmented at sentence level and inference data that is automatically segmented. Towards the same goal of training cost reduction, we participate in the simultaneous task with the same model trained for offline ST. The effectiveness of our lightweight training strategy is shown by the high score obtained on the MuST-C en-de corpus (26.7 BLEU) and is confirmed in high-resource data conditions by a 1.6 BLEU improvement on the IWSLT2020 test set over last year’s winning system.
Optimal Information Provision for Strategic Hybrid Workers

We study the problem of information provision by a strategic central planner who can publicly signal about an uncertain infectious risk parameter. Signalling leads to an updated public belief over the parameter, and agents then make equilibrium choices on whether to work remotely or in-person. The planner maintains a set of desirable outcomes for each realization of the uncertain parameter and seeks to maximize the probability that agents choose an acceptable outcome for the true parameter. We distinguish between stateless and stateful objectives. In the former, the set of desirable outcomes does not change as a function of the risk parameter, whereas in the latter it does. For stateless objectives, we reduce the problem to maximizing the probability of inducing mean beliefs that lie in intervals computable from the set of desirable outcomes. We derive the optimal signalling mechanism and show that it partitions the parameter domain into at most two intervals with the signals generated according to an interval-specific distribution. For the stateful case, we consider a practically relevant situation in which the planner seeks to enforce in-person work capacity limits that progressively get more stringent as the risk parameter increases. We show that the optimal signalling mechanism in this case can be obtained by solving a linear program. We numerically verify the improvement in achieving desirable outcomes using our information design relative to the no-information and full-information benchmarks.
Constraining the Progenitor System of the Type Ia Supernova 2021aefx

We present high-cadence optical and ultraviolet light curves of the normal Type Ia supernova (SN) 2021aefx, which shows an early bump during the first two days of observation. This bump may be a signature of interaction between the exploding white dwarf and a nondegenerate binary companion, or it may be intrinsic to the white dwarf explosion mechanism. In the case of the former, the short duration of the bump implies a relatively compact main-sequence companion star, although this conclusion is viewing-angle dependent. Our best-fit companion-shocking and double-detonation models both overpredict the UV luminosity during the bump, and existing nickel-shell models do not match the strength and timescale of the bump. We also present nebular spectra of SN 2021aefx, which do not show the hydrogen or helium emission expected from a nondegenerate companion, as well as a radio nondetection that rules out all symbiotic progenitor systems and most accretion disk winds. Our analysis places strong but conflicting constraints on the progenitor of SN 2021aefx; no current model can explain all of our observations.
Generalized covariant entropy bound in Lanczos-Lovelock gravity

In this paper, we investigate the generalized covariant entropy bound in the theory where the Einstein gravity is perturbed by the higher-order Lovelock terms. After replacing the Bekenstein-Hawking entropy with the Jacobson-Myers entropy and introducing two reasonable physical assumptions, we showed that the corresponding generalized covariant entropy bound is satisfied under a higher-order approximation of the perturbation from the higher-order Lovelock terms. Our result implies that the Jacobson-Myers entropy strictly obeys the entropy bound under the perturbation level, and the generalized second law of Lanczos-Lovelock gravity is also satisfied when the Einstein gravity is perturbed by the higher-order Lovelock terms.