Miracle-dz/UniFAR-FTUs huggingface dataset:
Investigation of malaria by microscopy among febrile outpatients of a semi-rural nigerian medical center: What happened to malaria control programs?

Background: Older reports estimate that malaria accounts for 60% of outpatient clinic encounters in Nigeria. However, current estimates suggest that malaria control programs have considerably reduced malaria-related morbidity and mortality on a global scale. The extent to which these programs impacted malaria prevalence in endemic countries such as Nigeria after the Millennium-Development Goals era may not have been fully appreciated. This study, therefore, assessed how common malaria was among febrile patients attending a semi-rural medical center in Nigeria. Materials and Methods: This was a cross-sectional study involving 290 randomly selected general and pediatric outpatients (who fulfilled inclusion criteria) attending the Federal Medical Centre, Birnin Kudu in August 2016. It assessed participants' clinical features, insecticide-treated net usage and presence of malaria parasitemia (confirmed by microscopy). Results: Participants' overall mean age was 18.4 ± 16.3 years (ranging from 0.25–62.0 years); 146 (50.3%) were females; 73.4% used insecticide-treated-net the previous night. Their mean overall temperature was 37.7°C ± 1.1°C. Overall malaria prevalence was 65.5%; however, the incidence was highest in ≥15 years age-group (30.3%) followed by ≤4 years age group (20.7%). Clinical features predicting malaria parasitemia were pallor (odds ratio [OR] = 5.03, 95% confidence interval [CI] = 1.96–14.42) and history of convulsion (OR = 4.06, 95% CI = 1.53–10.78). Their median parasite density was 1 ± 1.3. Clinical features poorly predicted malaria parasite density among participants. Conclusion: The malaria prevalence in this study was worryingly high. There is a need to review or modify current malaria control programs using more comprehensive strategies if reduction in the malaria-related morbidity and mortality in this and similar settings is desired.
Influence of parathyroid hormone on platelet counts and mean platelet volume in hemodialysis

Patients with end-stage kidney failure suffer from various hemostatic disorders. Uremic patients show a bleeding tendency which is mainly due to abnormalities of platelet function. In a study on 36 stable hemodialysis patients, we found a significant inverse correlation of platelet count with mean platelet volume and also a significant inverse correlation of platelet count with proportion of hemodialysis. In diabetic hemodialysis patients, a significant inverse correlation of platelet count with serum intact parathormone was detected. In a study on 36 stable hemodialysis patients, we found a significant inverse correlation of platelet count with mean platelet volume and also a significant inverse correlation of platelet count with proportion of hemodialysis. In diabetic hemodialysis patients, a significant inverse correlation of platelet count with serum intact parathormone was detected. The clinical consequence of these findings needs more attention in hemodialysis patients.
Pseudomyxoma peritonei and appendiceal carcinoma with peritoneal metastases: current management strategies

ABSTRACT Introduction: Pseudomyxoma peritonei (PMP) is a rare disease that has called worldwide attention to the management of cancer disseminated within the peritoneal surfaces of the abdomen and pelvis. This cancer spread is referred to as peritoneal metastases. In a historical perspective PMP was the first long-term success achieved in the management of peritoneal metastases. Areas covered: The treatment of PMP concerns two essential components. First, the surgeon uses surgical procedures including peritonectomy in order to remove all visible evidence of disease. Following a complete surgical resection, the abdomen is thoroughly washed for an extended time period (60–90 min) with a warm chemotherapy solution. The disease is especially suited for these aggressive local and regional treatment strategies. Expert opinion: The histology of the disease which estimates the aggressive versus benign nature of the process, the preoperative radiology which can estimate small bowel involvement, and the complete visible removal of all tumor constitute the important prognostic indicators by which to estimate the likelihood of long-term survival. A new standard of care for a rare disease has been established which carries a high likelihood of prolonged long-term survival as compared to prior efforts with serial debulking which always ended in a terminal state.
Right-Versus Left-Subclavian Central Venous Port for Patients with Malignant Tumor: A Retrospective Comparison of Adverse Events and Imaging Findings

Purpose: The optimal side for placement of a central venous port (CVP) remains unclear. The authors aimed to compare adverse events (AEs) and imaging findings according to CVP placement via the right and left subclavian vein (SCV) in patients with malignant tumor(s). Material and Methods: A total of 254 consecutive adult patients, who underwent CVP placement between January and August 2012, were included. Percutaneous ultrasound-guided access was attempted in the right SCV in 134 (59 men, 75 women; median age 61 years) and left SCV in 120 (58 men, 62 women; median age 61 years) patients. The primary tumor was colorectal (right, 17/ left, 71); upper gastrointestinal (33/7); bone and soft tissue (21/9); and others (63/33). A retrospective evaluation of technical success, AEs, and computed tomography findings was performed. Results: Technical success was achieved in 99% of patients in both groups. Median procedure time was 30 min in both groups. There were no statistically significant differences in intraprocedural AEs. In postprocedural AEs during a median follow-up of 347 (right)/530 (left) days, CVP placement in the left SCV was associated with a significantly higher rate of catheter occlusion (right, 0%; left, 5.8%). Both symptomatic venous thrombosis (right, 0.7%; left, 4.2%) and image-confirmed venous thrombosis (right, 4.8%; left, 21.8%) occurred more frequently in the left-CVP group. Conclusion: Left-CVP was associated with significantly higher rates of late AEs and venous thrombosis. Despite the inherent limitations of the retrospective study design and small sample size, re-evaluation of leftCVP may be required in patients with malignant tumor(s).
Comparing the Effects of Training Based on Continuous Care Model and Telehealth on Quality of Sleep in Pregnant Women

Background: Quality of sleep disorder is a common problem during pregnancy. Training based on continuous care model and telehealth has improved the quality of health care and may also ameliorate quality of sleep. Aim: The present study was conducted to compare the effects of training on the quality of sleep in pregnant women on the basis of continuous care model and telehealth. Method: This three-group clinical trial was performed in 2017 on 91 pregnant women visiting health centers in Mashhad, Iran. Orientation, sensitization, control and evaluation were carried out in the continuous care group, and four DVDs were watched by mothers in the telehealth group over the course of four weeks along with eight weeks of follow-up, and the routine care of health centers was administered for the control group. The Pittsburgh Sleep Quality Index (PSQI) questionnaire was completed at the end of weeks 8 and 12 after the start of the study. Data were analyzed in SPSS version 24 using Kruskal-Wallis statistical test. Results: The three groups were homogeneous in terms of demographic variables (P<0.05). The Kruskal-Wallis test results showed that the mean quality of sleep score before the intervention was homogeneous among the three groups (P=0.42), but it was significantly different (P<0.001) immediately after the intervention in the three groups of continuous care (4.4±1.7), telehealth (4.4±1.4), and control (9.0±3.7), and there was a significant difference four weeks post-intervention in the three groups of continuous care (3.5±2.1), telehealth (5.3±1.8), and control (10.7±3.1) (P<0.001). Implications for Practice: Training based on the continuous care model and telehealth can improve the quality of sleep in pregnant women. Considering that telehealth is a simpler and easier method, it can be used to boost the quality of sleep in pregnant women.
Proportion of Disrespectful and Abusive Care during Childbirth among Women in Khartoum State-2016

The access to good quality hospital care during childbirth has been identified as a key strategy in increasing maternal and infant survival. In spite of that, home delivery was 79.5% according to the Sudan 2010 Household Survey. Previous evidence tells that one of the major factors deterring pregnant women from delivering at a health facility is disrespectful and abusive treatment by the health care providers. This study attempted to measure the proportion of disrespectful and abusive care (DA therefore, health administrators should study and validate these protocols and their proper implementation.
Research progress and future directions on intraductal papillary mucinous neoplasm: A bibliometric and visualized analysis of over 30 years of research

Background: Malignant change from low-grade dysplasia to high-grade dysplasia and invasive carcinoma following an adenoma-carcinoma sequence is becoming more common in intraductal papillary mucinous neoplasm (IPMN) of the pancreas. The aim of this study is to analyze their main characteristics and recent research trends in IPMNs and consequently create better understandings of the current situation and trends. Methods: A comprehensive search was performed in The Science Citation Index Expanded of the Web of Science. All articles between 1990 and 2021 were searched. VOS viewer (Leiden University, Leiden, Netherlands) was used for a qualitative and quantitative analysis of keywords, constituting maps based on co-occurrence matrix. Results: A total of 1658 eligible articles were screened among the 3950 identified articles for this subject. Finally, 879 articles were included in this study. Many articles on IPMN have been published in Japan and South Korea. Tanaka published the highest number of articles (n = 26, citations = 11,143). The Pancreas published the highest number of articles. (n = 100, citations = 2533). These articles were grouped into 4 clusters including basic research, disease overview, management/prognosis and malignant IPMN by using bibliometric keywords network analysis. Overlay visualization demonstrates, a trend of the studies has been changed from basic research or disease to management or prognosis. Conclusions: In this study, we found and highlight the most cited and influential articles related to IPMN. Plus, this study analyzed global research trends in IPMN over the past 30 years and provides insight into the features and research hotspots of the articles in IPMN research.
A Comparative Study of Pet Owners and Non-Pet Owners to find out the Difference between their Physical, Mental, and Social Well-Being

Introduction: The human-animal bond is a mutually beneficial and dynamic relationship between people and animals that influence the health and well-being of both. While many of us intuitively understand the benefits of positive interactions with animals in our lives, an emerging body of research is recognizing the impact the human-animal bond can have on individual and community health. Objective: The objective of this study was to study the effects of keeping pets on the physical, mental, social, and emotional well-being of participants. Methodology: A cross-sectional study was done on predecided sample of 120, i.e., 60 pet owners and 60 non-pet owners randomly selected from residential areas of Indore city, to compare the effects of keeping pets on the physical, mental, social, and emotional well-being of participants using appropriate scales for various parameters. Results: About 63.33% of pet owners were found physically healthy, while only 20% of non-owners were physically healthy and 76.66% were having mild-to-moderate physical problems. Pet owners are found to be happier in comparison to non-pet owners (P < 0.001). None of the pet owners were found to have low self-esteem, as opposed to 36.6% of non-pet owners who were found to have low self-esteem. 43.33% of non-pet owners were found to have moderate anxiety levels while only 13.33% of owners had moderate anxiety (P = 0.011). 86.66% of pet owners were found to have no depression; in contrast, 40% of non-owners had severe depression (P < 0.001). 86.66% of pet owners were found to have no depression; in contrast, 40% of non-owners had severe depression (P < 0.001). Only 46.66% of pet owners were found to be lonely as compared to 80% of non-pet owners. Conclusion: The study shows that pet owners are physically more healthy, mentally more happier, less anxious, less depressed and are more social in comparison to non-pet owners. Key words: Pet owners, non-pet owners, physical, mental and social well being
Strategic Aeromedical Evacuation (AE): Examining Biological and Psychosocial Stress in AE Patients

Abstract Aeromedical evacuation (AE) transports a military patients with a variety of medical conditions from foreign theaters back to the United States for medical treatment. Biological (e.g., alpha-amylase, immunoglobulin A, cortisol, blood pressure, and heart rate) and psychosocial stress measures were collected in (N = 36) AE patients upon U.S. arrival and before transport to their final military destinations. Biological stress measures were not significantly related to psychosocial measures. Findings provide an important understanding of stress in the AE population and a foundation from which to evaluate future stress mitigation strategies and gage the need for supportive care in the AE system.
Assessment of factors associated with poor glycemic control among patients with Type II Diabetes mellitus

Background: Glycemic control remains the major therapeutic objective for prevention of target organ damage and other complications arising from diabetes. In addition, elucidation of various determinants of poor glycemic control may contribute to a clearer understanding of modifiable antecedents of diabetes-related complications and help to achieve improved diabetic control and patient outcomes. Method: Two hundred twenty patients of Type II diabetes mellitus were taken after Informed consent. Patients who fulfill Inclusion and Exclusion Criteria were participated for the study. A Case record form was administered to these patients, which included details regarding the socio-demographic, anthropometric, metabolic, disease profile and diabetes self-care practices of the Type II diabetic patients. Result: Based on HbA1c values, majority of diabetic patients had poor glycemic control (91.8%) while only 8.2% Type II diabetic patients had good (ideal) glycemic control. Statistically significant difference (P = 0.044) was found between patients with good and poor glycemic control in relation with BMI (P = 0.044), central obesity (P < 0.001), dyslipidemia (P < 0.001) and diabetes self-care practices {glucose management (P = 0.003), dietary control (P = 0.006), sum scale (P = 0.028)}. Conclusion: Majority of Type II diabetic patients had poor glycemic control. Factors affecting glycemic control included BMI, central obesity, dyslipidemia and diabetes self-care practices (glucose management and dietary control). In clinical practice, optimal glycemic control is difficult to obtain on a long-term basis because the reasons for poor glycemic control in Type II diabetes are complex. Both patient and health care provider related factors may contribute to poor glycemic control. A variety of factors are identified in influencing glycemic control including age, sex, education, marital status, BMI, smoking, diabetes duration, and type of medications [5]. However, the results are not consistent and, in most instances, more than half of the variance in HbA1c levels is not explained [6]. Therefore studies focused on determining the factors predominantly associated with poor glycemic control among Type 2 diabetics attending any particular hospital set up, are warranted so that appropriate interventions can be planned at the level of the patient, physician and Institute. This kind of research into diabetes mellitus will provide useful insights into the current glycemic control of diabetic patients in our set up. Type II diabetic patients were classified as having good and poor glycemic control. Data on glycemic control pattern was linked to various measures of treatment modality (Oral Hypoglycemic agents, Insulin, OHA + Insulin), risk factors (Hypertension, Dyslipidemia,), socio-demographic (Age, Gender, Socio-economic status), metabolic (Lipid Profile), anthropometric (BMI, Waist Circumference), disease *Correspondence to: Ipseeta R Mohanty, Department of Pharmacology, MGM Medical College, Navi Mumbai 410209, India, E-mail: ipseetamohanty@yahoo.co.in
The Iranian Hyalomma (Acari: Ixodidae) with a key to the identification of male species

The taxonomic status of ticks in the genus Hyalomma , as prominent vectors of domestic animal and human pathogen agents as well as hematophagous parasites of all terrestrial animals has a problematic history due to variability. The present paper is based on our observations on the Iranian Hyalomma species during 2009 to 2013. In this study, for nine Hyalomma species including H. aegyptium , H. anatolicum , H. asiaticum , H. detritum , H. dromedarii , H. excavatum , H. marginatum , H. rufipes and H. schulzei , morphologic characteristics and some notes on their variability, biology and distribution are presented. In this paper, diagnoses, host information, distribution data, illustrations of adult males and a taxonomic key to the native Hyalomma species of Iran are provided to facilitate their identification.
Survey of quality of life of patients with breast cancer among women at Shahid Beheshti University of Medical science and Health service 2017

Background and Aims : Breast cancer is the most common type of cancer diseases among women. The survival rate of breast cancer patients is long and, as a result, patients are greatly affected by cancer, its complications and consequences. Materials and Methods : The research design was descriptive – cross sectional. About 150 patients (women) with breast cancer were candidate for chemotherapy referred to the ward of Oncology in Shohada Tajrish and Taleghani Hospitals, both under the auspicious of Shahid Beheshti University of Medical science, 2017. The standard Quality of life Questionnaire (EROTC QLQ_C30) and its breast cancer supplementary measure (QLQ-BR 23) Questionnaire developed by the European Organization for Research and treatment of cancer were respectively used to measure the quality of life and for demography, within one stage. Finally, the data was analyzed using SPSS16 statistical software through ANOVA and Pearson tests. All ethical issues were considered throughout the study. Results : The average age of women whom surveyed was 47.81±8.21, which 74.7 percent of them were married. The average score of the global health status of respondents undergone the survey was 538818.20±. Among the functional scores, the highest score was related to cognitive indexes 68.77± 30.30. Economic difficulties showed the highest score of 69.11 27.33± among symptom scales. Physical,emotional and cognitive functioning, and also the disease symptoms such as fatigue, nausea and vomiting, pain, dyspnoea, insomnia, constipation and economic difficulties were among the variables demonstrating significance relationship with quality of life in Univariate Analysis. Conclusion : The results of this study show the inappropriate conditions regarding the quality of life in some general and specific symptom scales of the patients under the survey. Therefore, the importance of paying more attention to this matter and designing of suitable actions for enhancing the quality of their life is expected. Keyword : Breast cancer, Quality of life, Women
Impact of Mandatory Advising on Retention and Persistence of Male African American and Latinx Community College Students.

This correlational research study examined the effects of mandatory advising on the retention and persistence of African American and Latinx male community college students who attended an urban community college in the Midwest. Additionally, the study also examined the effects of mandatory advising on all males, African American and Latinx students overall and all students. The study used data collected from two separate cohorts, mandatory advising and non-mandatory advising. The retention and persistence of all groups were analyzed using a Chi-square statistical analysis. The results of this study revealed that there was statistical significance of p = . 000 between mandatory advising of all students and persistence and there was a statistical significance of p = . 000 between the persistence of men and mandatory advising.
The symptoms and histopathology of many virus diseases depend not so much on damage to cells by virus but on the immunobiological reaction to the infection

The symptoms and histopathology of many virus diseases depend not so much on damage to cells by virus but on the immunobiological reaction to the infection. Nowhere is this more clearly illustrated than with murine lymphocytic choriomeningitis (LCM) 1 virus (1). The basic features of the system were established by Traub in the 1930's (2): mice that received virus transplacentally or shortly after birth developed a life-long peristent infection, whereas the outcome in mice infected as adults was quite different. In the latter case peripheral injection usually produced an abortive immunizing infection, whereas intracerebral (i.c.) injection resulted in choriomeningitis and death within 7-9 d. The immunological basis for this choriomeningitis has been investigated intensely during the last 10 yr. The early observations of Rowe (3) showing lack of correlation between serum antibody level and immunity, followed by the finding that thymectomized mice could not be killed by i.c. infection (4), were the first indications of the central role of thymus-derived lymphocytes in fatal lymphocytic choriomeningitis. Following the pioneering work of Volkert (5), Gilden et al. (6) established a model system for adoptive transfer of lymphocytes into adult i.c. -infected mice. In these elegant studies, Cole and co-workers (7) demonstrated, by selective reconstitution of the immune system of cyclophosphamide (CY)-spared mice, that only immune lymphocytes bearing thymus-derived antigens caused rapid convulsive death. Furthermore, Johnson and colleagues (8) conclusively demonstrated that B cells and their secreted products played no role in pathogenesis by showing that mice markedly depleted of immunoglobulin (Ig)-bearing lymphocytes were just as susceptible as normal mice to LCM-induced central nervous system (CNS) disease. For several years we have focused our attention on the mechanisms of LCMinduced acute CNS disease by studying L C M strains lacking the ability to kill adult i.c. -infected mice in the classic convulsive manner (9, 10). One question asked was: do these so-called "docile" virus strains induce virus-specific T cell responses, and if so, are these responses qualitatively or quantitatively different from those induced by the well-studied so-called "aggressive" strains? It was first necessary to assess T cell