Miracle-dz/UniFAR-FTUs huggingface dataset:
Peer-to-Peer Human Milk-Sharing Among Israeli Milk Donors: A Mixed-Methods Study in the Land of Milk and Honey

Background: Evidence is lacking on the phenomenon of peer-to-peer human milk-sharing in the Middle East, specifically, in Israel. Research Aims: This study aimed to uncover peer-to-peer human milk-sharing in Israel, learn about how and whether donors engage in safe milk handling and storage practices, and assess knowledge about human milk and breastfeeding among this milk-sharing population. We also aimed to investigate donors’ selectiveness in their decisions about to whom they donate their milk and their perceptions about the sale and purchase of human milk. Methods: We conducted a semi-structured online survey, including both closed- and open-ended questions and used mixed methods to analyze responses descriptively. We used non-probability sampling to obtain a broad sample of human milk donors. Results: Out of 250 completed surveys, most participants (87.2%, n = 218) reported engaging in safe milk-sharing practices and were generally knowledgeable about the health risks associated with milk-sharing. Participant religiosity was associated with somewhat lower hygiene practices (r = −0.15, p ≤ .05). Most of the participants (81.7%, n = 190) were against the sale of human milk. Participants generally expressed no preference about the recipient of their milk, with some exceptions. Conclusion: The milk-handling and storage practices of the participants in this study suggest a need to improve knowledge and awareness of safe milk storage temperature and the importance of washing hands before pumping milk, particularly within the religious sector. We propose that guidelines about safe milk-sharing practices be written and adopted by the Israeli Ministry of Health, and communicated through pediatricians, family doctors, nurses in Mother and Child Clinics (In Hebrew: Tipat Halav), and social media.
Past 6-Month Prevalence of IPV Victimization among Transgender and Gender-Diverse Undergraduate Students: A Brief Report

Research has largely neglected the issue of intimate partner violence (IPV) among transgender and gender-diverse (TGD; e.g., nonbinary and genderqueer) individuals. However, existing research suggests that TGD individuals are disproportionately affected by IPV. The current study sought to explore if and how rates of IPV vary among subgroups of TGD undergraduate students and contextual factors of IPV among TGD individuals including the co-occurrence of multiple forms of IPV victimization, the type of relationship in which IPV occurred, and the gender identity of the IPV perpetrator. Participants were 280 TGD undergraduate students attending 20 medium- and large-sized residential public universities across the contiguous United States. Of the entire sample of TGD undergraduate students (N = 280), a total of 27.5% endorsed past 6-month IPV victimization (20.0% psychological, 6.1% physical, 8.9% sexual, 11.4% coercive control, and 5.7% LGBTQIA+-specific). Among only the participants who endorsed past 6-month IPV victimization (N = 77), 45.4% reported one form of IPV victimization, 26.0% two forms, 22.1% three forms, and 6.5% four forms. Further, 41.3% of TGD IPV victims were in a casual relationship, 56.0% were in a serious relationship, and 2.7% were in multiple relationship types. Finally, 55.8% of victims reported their perpetrator was a man, 22.1% a woman, and 22.1% a TGD individual. No significant differences in rates of IPV were found between TGD respondents. These data highlight the urgent need for programming efforts on college campuses that are specifically designed to prevent and address IPV among and against TGD students. Future research should evaluate universal- and population-specific risk and protective factors for IPV among TGD individuals to inform prevention and response efforts for this highly vulnerable population.
Reappraisal of mast cell leukemia based on a single institution review of 16 cases: Mast cell morphology determines clinical outcome

Cytologic abnormalities of atypical mast cells in mastocytosis. The mature mast cells have oval-shaped nuclei, cytoplasmic hypogranulation and spindle-shaped cytology. or well-differentiated displaying a round nucleus with condensed chromatin, and abundant dense cytoplasmic granulations. Immature mast cells include promastocytes and metachromatic blast-like forms.
Estimation of shear stress heterogeneity along capillary segments in angiogenic rat mesenteric microvascular networks

Fluid shear stress is thought to be a regulator of endothelial cell behavior during angiogenesis. The link, however, requires an understanding of stress values at the capillary level in angiogenic microvascular networks. Critical questions remain. What are the stresses? Do capillaries experience similar stress magnitudes? Can variations explain vessel‐specific behavior? The objective of this study was to estimate segment‐specific shear stresses in angiogenic networks.
Heat shock protein 27 regulates myogenic and self-renewal potential of bovine satellite cells under heat stress

Abstract While satellite cells play a key role in the hypertrophy, repair, and regeneration of skeletal muscles, their response to heat exposure remains poorly understood, particularly in beef cattle. This study aimed to investigate the changes in the transcriptome, proteome, and proliferation capability of bovine satellite cells in response to different levels of heat stress (HS) and exposure times. Satellite cells were isolated from 3-mo-old Holstein bulls (body weight: 77.10 ± 2.02 kg) and subjected to incubation under various temperature conditions: 1) control (38 °C; CON), 2) moderate (39.5 °C; MHS), and extreme (41 °C; EHS) for different durations ranging from 0 to 48 h. Following 3 h of exposure to extreme heat (EHS), satellite cells exhibited significantly increased gene expression and protein abundance of heat shock proteins (HSPs; HSP70, HSP90, HSP20) and paired box gene 7 (Pax7; P < 0.05). HSP27 expression peaked at 3 h of EHS and remained elevated until 24 h of exposure (P < 0.05). In contrast, the expression of myogenic factor 5 (Myf5) and paired box gene 3 (Pax3) was decreased by EHS compared to the control at 3 h of exposure (P < 0.05). Notably, the introduction of HSP27 small interference RNA (siRNA) transfection restored Myf5 expression to control levels, suggesting an association between HSP27 and Myf5 in regulating the self-renewal properties of satellite cells upon heat exposure. Immunoprecipitation experiments further confirmed the direct binding of HSP27 to Myf5, supporting its role as a molecular chaperone for Myf5. Protein–protein docking algorithms predicted a high probability of HSP27–Myf5 interaction as well. These findings indicate that extreme heat exposure intrinsically promotes the accumulation of HSPs and modulates the early myogenic regulatory factors in satellite cells. Moreover, HSP27 acts as a molecular chaperone by binding to Myf5, thereby regulating the division or differentiation of satellite cells in response to HS. The results of this study provide a better understanding of muscle physiology in heat-stressed cells, while unraveling the intricate molecular mechanisms that underlie the HS response in satellite cells.
More buildings about songs and food: A case study of Omaha's Slowdown project.

The success of independent rock music ("indie rock"), once a marginalized sub-genre of the rock idiom and now a globally recognized cultural force, has impacted the urban landscape of Omaha, Nebraska via the mixed-use urban redevelopment project, "Slowdown" - a result of cultural production by the city's successful indie rock business entities. While geographic research has previously analyzed urban redevelopment initiated by fine artists, the event of indie rock music being a catalyst for urban redevelopment has never been considered in a geographic scope. By examining the topics of affordable technological tools, Omaha's reduced cost-of-living, and cooperative efforts by city leaders, insight into how an indie rock "scene" can become a successful urban redevelopment catalyst is gained.
Molecular interactions in short-chain perfluoroalkyl carboxylic acids and aqueous solutions

The presence of short-chain per- and polyfluoroalkyl substances in water poses a major health and environmental challenge. Here, we have performed high-energy small- and wide-angle X-ray scattering measurements on CF3[CF2]nCOOH (where n = 1, 2, 3 represents the chain length) and their aqueous solutions at 10% mole concentrations to characterize their molecular interactions at the atomic and nanometer length scales. The experimental wide-angle structure factors have been modelled using Empirical Potential Structural Refinement. The oxygen–oxygen partial X-ray pair distribution functions show that the coordination number between the hydroxyl oxygen on the acid and surrounding oxygen water molecules increases significantly with acid chain length, rising from 3.2 for n = 1 to 4.1 for n = 3. The small-angle scattering is dominated by a sharp, high-intensity peak at Q1 ∼ 0.2 Å−1 and a smaller peak at Q2 = 1.2 Å−1 for n = 3, both of which decrease with decreasing chain length. The Q2 peak is attributed to groups of adjacent non-bonded acid molecules, and Q1 has contributions from both correlations between acid molecules and water–water interactions. In all cases, the models show nanoscale aggregation occurs in the form of denser channels of winding hydrogen-bonded chains, approximately 20 water molecules in length, surrounding clusters of acid molecules. This article is part of the theme issue 'Exploring the length scales, timescales and chemistry of challenging materials (Part 2)'.
Analysis of a hydrologic balance model and Penman-Monteith evapotranspiration estimating methods

approved: Redacted for Privacy Richard 11-. Cuenca The major objectives of this study were an evaluation of the Meteorological Office Rainfall and Evaporation Calculation System (MORECS) evapotranspiration (ET) model using the Penman-Monteith equation and comparison of the MORECS and measured surface resistance. Meteorological, soil and plant parameters were measured in an alfalfa field over two growing seasons. Soil water content was measured daily using the neutron probe. Stomatal resistance was measured with a diffusion porometer two days per week and leaf area was measured with a portable areameter. The ET obtained using the MORECS model was compared with that calculated using a hydrologic balance model (Cuenca, 1988) and the WrightPenman equation (Wright, 1982). The hydrologic balance model applied on a daily basis produced large variations in estimated ET both among individual access tubes and from day-to-day. Drainage compensation, dew compensation and moving average smoothing procedures were tested to reduce this high variation. Completely satisfactory results were not obtained with any of these smoothing procedures. An error analysis was performed to identify sources of variation in depth of stored soil moisture. The variation was associated with inaccuracy in the neutron probe calibration equation and variance in probe readings at a given time and location. The standard error of depth of stored water is reduced with an increase in the number of neutron probe measurements per depth layer. Four readings per monitored depth layer would reduce this standard error by approximately fifty percent. The total variance in depth of stored water over the soil profile is also reduced by decreasing the depth layer thickness. The MORECS model underestimated surface resistance early in the growing season. The difference between MORECS and measured surface resistance was negligible at full cover. Allen's (1986) empirical equation overestimated the surface resistance for the total growing season. An average minimum surface resistance of 18 s/m was found for alfalfa growing in Corvallis. A difference of approximately 10 percent in the cumulative ET over a period of two months was found using the MORECS minimum surface resistance of 40 s/m compared to a measured value of 17.6 s/m. The most accurate ET estimates therefore require a locally determined surface resistance. ANALYSIS OF A HYDROLOGIC BALANCE MODEL AND PENMAN-MONTEITH EVAPOTRANSPIRATION ESTIMATING METHODS by Osmar Alves Carrijo A THESIS submitted to Oregon State University in partial fulfillment of the requirements for the degree of DOCTOR OF PHILOSOPHY Completed May 3, 1988 Commencement June 5, 1988
Science in Context: Readings in the Sociology of Science

This collection of eighteen readings provides a basic text for undergraduates taking sociology of science courses. A general survey of articles published between 1961 and 1981, the book is also a useful overview for students taking courses in social and political studies of science; science, technology, and society; and "social issues" components of courses in the environmental sciences, geography, philosophy, and history of science.The editors have organized the book around "the relationship between the subculture of science and the wider culture which surrounds it. Looked at from this perpective, science is primarily a source of knowledge and competence. Thus to stress its interaction with its context not only highlights these aspects of science which most people find of overriding pragmatic interest, but also raises important basic issues concerning credibility, the distribution of authority in society, and the nature of the interaction between different forms of culture. "Essays are grouped in five sections: The Organization of Academic Science: Communication and Control; The Culture of Science; The Interaction of Science and Technology; The Interaction of Science and Society; Science as Expertise. The editors have added a general introduction, part introductions, bibliographical notes, and a lengthy bibliography.Barry Barnes is Lecturer at the Science Studies Unit, University of Edinburgh, and editor of an earlier version of this book, "The Sociology of Science," published in the Penguin Sociology Readings series and now out of print. David Edge is Director of The Science Studies Unit at the University of Edinburgh and a joint editor of the journal, "Social Studies of Science. "
UNE CLASSIFICATION GEOTECHNIQUE DES CRAIES DU NORD UTILISEE POUR L'ETUDE DE STABILITE DES CARRIERES SOUTERRAINES

DANS LE CADRE DE L'ETUDE DE STABILITE DES CARRIERES SOUTERRAINES DU NORD DE LA FRANCE, LE CERCHAR A EFFECTUE PLUS DE 750 ESSAIS DE RESISTANCE A LA COMPRESSION SIMPLE, SUR DES ECHANTILLONS DE CRAIE EN PROVENANCE DE 25 SITES. LE TRAITEMENT STATISTIQUE DE CETTE INFORMATION, PAR LES TECHNIQUES D'ANALYSE DES DONNEES USUELLES, A MIS EN EVIDENCE DES CORRELATIONS ENTRE PARAMETRES PHYSIQUES ET MECANIQUES. LORS D'ETUDES SOMMAIRES DE STABILITE, CES LIAISONS PERMETTENT D'ESTIMER LA RESISTANCE A LA COMPRESSION SIMPLE AVEC UNE PRECISION SUFFISANTE POUR ETRE OPERATIONNELLE (A).
The Minimum Wage and the Great Recession: Evidence of Effects on the Employment and Income Trajectories of Low-Skilled Workers

We estimate the minimum wage's effects on low-skilled workers' employment and income trajectories. Our approach exploits two dimensions of the data we analyze. First, we compare workers in states that were bound by recent increases in the federal minimum wage to workers in states that were not. Second, we use 12 months of baseline data to divide low-skilled workers into a "target" group, whose baseline wage rates were directly affected, and a "within-state control" group with slightly higher baseline wage rates. Over three subsequent years, we find that binding minimum wage increases had significant, negative effects on the employment and income growth of targeted workers. Lost income reflects contributions from employment declines, increased probabilities of working without pay (i.e., an "internship" effect), and lost wage growth associated with reductions in experience accumulation. Methodologically, we show that our approach identifies targeted workers more precisely than the demographic and industrial proxies used regularly in the literature. Additionally, because we identify targeted workers on a population-wide basis, our approach is relatively well suited for extrapolating to estimates of the minimum wage's effects on aggregate employment. Over the late 2000s, the average effective minimum wage rose by 30 percent across the United States. We estimate that these minimum wage increases reduced the national employment-to-population ratio by 0.7 percentage point.
Engagement and Anonymity in Online Computer Science Course Forums

Online discussion boards, designed to facilitate learning from peers and instructors in an accessible space, are a vital part of course design, especially in large scale computer science classes. Previous work has shown that women in computer science tend to use anonymity more often than men on these boards, a trend not found in humanities, social science or business courses. In this work, we build on these findings using an intersectional lens, analyzing both gender and race/ethnicity. We find this combined analysis reveals differences in anonymity that are not apparent when examining gender alone. For example, we find a significantly greater difference in anonymity use between Hispanic men and women than would be expected from analyzing race/ethnicity and gender independently. We additionally analyze type of content (e.g., questions, answers), course, platform, and data source to characterize the many factors at play in measuring students’ choice to participate anonymously. In doing so, we show that different approaches used in prior work for eliciting information on gender — whether using registrar data, a survey, or imputing gender based on name — changes how over of students are classified, particularly affecting nonbinary students and Asian students. Understanding when students participate anonymously can help educators and platform designers to make students’ experience of online discussion boards more welcoming.
Issues of informed consent for non-specialists conducting colorectal cancer screenings

Abstract The United States is currently facing a physician shortage crisis including a lack of specialist providers. Due to this shortage of specialists, some primary care providers offer colorectal cancer screenings in communities with few gastroenterologists, especially in under-resourced areas such as rural regions of the United States. However, discrepancies in training and procedural outcomes raise concerns regarding informed consent for patients. Because osteopathic physicians play a critical role in addressing the physician shortage in these under-resourced communities, this commentary may be especially useful because they are likely to encounter these ethical complexities in their day-to-day practice.
Length-weight relationships of bivalves from coastal waters of Korea

Parameters a and b of the length (L)-weight (W) relationship W = a ╖ Lb are presented for 17 commercial bivalve species collected from the southwest coastal waters of Korea. Estimates of b varied between 2.44 (Atrina pinnata japonica) and 3.31 (Scaphara broughtonii) with a mean of 2.891 (▒ 0.212). A total of 2 107 specimens were analyzed for this study. The length-weight relationship was isometric in most of the species.
Myelin-reactive B cells exacerbate the severity of CD4+ T cell-driven CNS autoimmunity in an IL-23-dependent manner

Multiple sclerosis (MS) is an autoimmune disorder of the central nervous system (CNS) that has traditionally been considered a T cell-mediated disease. However, accumulating evidence points to a crucial role for B cells in disease processes. IgH[MOG] mice possess a transgenic immunoglobulin heavy chain derived from a monoclonal antibody specific to myelin oligodendrocyte glycoprotein (MOG), a key target for autoimmune responses. Here, using the experimental autoimmune encephalomyelitis (EAE) model of MS, we investigated the susceptibility of IgH[MOG] mice to CD4+ T cell-driven disease that was induced by active immunization with MOG[35-55] autoantigen. We found that immunized IgH[MOG] mice rapidly developed severe EAE, characterized by the aggregation of T and B cells in the CNS meninges. We observed an increased presence of class-switched and inflammatory cytokine-positive B cells in the IgH[MOG] CNS, as well as a greater frequency of IL-17- and GM-CSF-producing CD4+ T cells. Production of the Th17 maintenance factor IL-23 was increased from IgH[MOG] CNS-infiltrating B cells, and in vivo blockade of IL-23p19 strongly attenuated disease severity in IgH[MOG] mice. Strikingly, we observed an increased frequency of PD-1+CXCR5- T peripheral helper (Tph)-like cells in the CNS parenchyma and dura mater of IgH[MOG] mice. Both Tph accumulation in the CNS, as well as meningeal inflammation, were again sharply reduced upon IL-23p19 blockade in vivo. Notably, CNS-infiltrating B and Tph cells from IgH[MOG] mice showed an upregulation of genes related to neurodegeneration and oxidative phosphorylation, and IL-23 blockade reduced ROS production from these cells in vivo. Altogether, these data show that MOG-specific B cells contribute to severe CD4+ T cell-driven EAE by promoting CNS accumulation of Th17 and Tph cells, as well as tertiary lymphoid organs in the CNS meninges, in an IL-23 dependent manner.
Reliability of the TMS-evoked potential in dorsolateral prefrontal cortex

Background We currently lack a robust and reliable method to probe cortical excitability noninvasively from the human dorsolateral prefrontal cortex (dlPFC), a region heavily implicated in psychiatric disorders. We recently found that the strength of early and local dlPFC single pulse transcranial magnetic stimulation (TMS)-evoked potentials (EL-TEPs) varied widely depending on the anatomical subregion probed, with more medial regions eliciting stronger responses than anterolateral sites. Despite these differences in amplitude of response, the reliability at each target is not known. Objective To evaluate the reliability of EL-TEPs across the dlPFC. Methods In 15 healthy subjects, we quantified within-session reliability of dlPFC EL-TEPs after single pulse TMS to six dlPFC subregions. We evaluated the concordance correlation coefficient (CCC) across targets and analytical parameters including time window, quantification method, region of interest, sensor-vs. source-space, and number of trials. Results At least one target in the anterior and posterior dlPFC produced reliable EL-TEPs (CCC>0.7). The medial target was most reliable (CCC = 0.78) and the most anterior target was least reliable (CCC = 0.24). ROI size and type (sensor vs. source space) did not affect reliability. Longer (20-60 ms, CCC = 0.62) and later (30-60 ms, CCC = 0.61) time windows resulted in higher reliability compared to earlier and shorter (20-40 ms, CCC 0.43; 20-50 ms, CCC = 0.55) time windows. Peak-to-peak quantification resulted in higher reliability than the mean of the absolute amplitude. Reliable EL-TEPs (CCC up to 0.86) were observed using only 25 TMS trials for a medial dlPFC target. Conclusions Medial TMS location, wider time window (20-60ms), and peak-to-peak quantification improved reliability. Highly reliable EL-TEPs can be extracted from dlPFC after only a small number of trials. Highlights Medial dlPFC target improved EL-TEP reliability compared to anterior targets. After optimizing analytical parameters, at least one anterior and one posterior target was reliable (CCC>0.7). Longer (20-60 ms) and later (30-60 ms) time windows were more reliable than earlier and shorter (20-40 ms or 20-50 ms) latencies. Peak-to-peak quantification resulted in higher reliability compared to the mean of the absolute amplitude. As low as 25 trials can yield reliable EL-TEPs from the dlPFC.