Miracle-dz/UniFAR-FTUs huggingface dataset:
Orbital Order and Spontaneous Orthorombicity in Iron Pnictides

Phase diagram of the Iron Pnictide families of superconductors show a tetragonal to orthorhombic transition, sometimes coincident with the antiferromagnetic phase transition and sometimes at temperatures clearly above the antiferromagnetic phase transition. Inelastic neutron scattering spectra show exchange constants with strong spatial anisotropy. Recent photoemission measurements in mechanically detwinned samples show clear evidence of unequal orbital occupation and strikingly diﬀerent spectra for dxz and dyz iron orbitals. Scanning Tunneling Microscopy and transport measurements have also shown substantial orthorhombicity in these materials. We discuss a simple microscopic picture for coupled spin and orbital degrees of freedom as the root cause for such an anisotropy and discuss the extent to which this picture can be distinguished from spin-frustration induced Ising nematic ﬂuctuations as being the dominant driver for this phenomena.
Lung cancer screening study from a smoking population in Kunming.

OBJECTIVE Yunnan, China, is a central tobacco-producing region with a large smoking population and an increasing incidence of lung cancer in recent years. This study aimed to understand the incidence of lung cancer and the characteristics of lung nodules on low-dose computed tomography (LDCT) scans of the chest in a long-term smoking population in Kunming. PATIENTS AND METHODS Long-term smokers in Kunming who were not at risk of evident lung disease symptoms were recruited through recommendation and publicity by the Kunming University of Science and Technology. RESULTS Among 375 cases eligible for inclusion,14 cases of lung cancer were detected with a detection rate of 3.73% (95% CI: 2.55%-4.27%), including one case of squamous carcinoma, one case of small cell lung cancer, seven cases of adenocarcinoma of the lung and five cases of early-stage lung cancer (35.71%). In the group of < 6 mm solid nodules and < 5 mm non-solid nodules, no lung cancer was detected in 201 cases; lung cancer was detected in 14 cases in 61 cases, and there was a statistical difference between the two groups (p < 0.05). CONCLUSIONS The lung cancer detection rate in long-term smokers was high, with the type predominantly adenocarcinoma and a high incidence of lung nodules, and increased when solid nodules≥6 mm or non-solid nodules ≥ 5 mm were present. It is recommended that screening for lung cancer by LDCT of the chest be introduced in the male smoking population who meet the risk factors and that screening for lung cancer in women should be redefined as a high-risk factor.
Is telehealth an effective and feasible option for improving falls-related outcomes in community-dwelling adults with neurological conditions? A systematic review and meta-analysis

Objective To determine the effectiveness of telehealth interventions in reducing community falls risk or rates compared to equivalent in-person interventions in adults with neurological conditions. Data Sources Eight electronic databases, trial registries and search engines were searched for the concepts ‘falls’, ‘neurological conditions’, and ‘telehealth’, limited to English language, from inception until August 2022. Review methods Search for original research where the intervention was delivered via synchronous videoconferencing with the aim of reducing falls and falls-related outcomes. Screening and risk of bias assessment were completed by two independent researchers. Outcome data included falls rates, falls-related outcomes, safety, feasibility, and acceptability. Risk of bias was assessed using the ROB-2 and ROBINS-I tools. Quality of evidence was rated with the grading of recommendations, assessment, development and evaluation (GRADE) approach. Results Seventeen studies with 581 participants were included; six were randomised controlled trials. Risk of bias ranged from low to high. Only one study (n = 76) reported falls and did not find differences between telehealth and in-person physiotherapy. There was low-quality evidence that telehealth interventions improve balance outcomes more than face-to-face interventions (pooled between-group mean difference 2.48 Berg Balance Scale units, 95%CI 0.77 to 4.20). Fear of falling was not different between intervention delivery modes. Conclusion Findings suggest that telehealth delivered falls prevention interventions are safe, feasible and acceptable in community-dwelling adults with neurological conditions, however, data related to effectiveness in reducing falls is limited. Low-quality evidence suggests that telehealth may deliver similar or better outcomes for standing balance in this population. PROSPERO Registration: (CRD42021240167).
Youth Perspectives on Menthol Sales Restrictions in Minneapolis and Duluth, Minnesota

Although menthol cigarettes are a starter product for youth, menthol was exempted from the 2009 Tobacco Control Act, which banned all other characterizing flavors. Minneapolis and Duluth, Minnesota, implemented menthol tobacco sales restrictions in 2018 to advance health equity for youth, African American, lesbian, gay, bisexual, trans, and queer (LGBTQ), and other communities adversely affected by menthol. This evaluation assesses the policy impact on youth access to menthol tobacco, exposure to menthol advertising, and tobacco use. A core group of youth aged 14 to 17 years (n = 30) was recruited from Minneapolis and Duluth to gather data through photo voice and peer interviews 2 months before and after policy implementation. This evaluation shares the results of focus groups with these core youth where they reflected on what they observed in the community and heard from peers. The core youth identified and categorized emergent themes using the evaluation questions. Following the focus groups, the evaluation staff used these preliminary themes and coded remaining transcripts. The core youth had mixed reactions to the impact of policies on access and use because many tobacco users in their age group obtain tobacco informally through peers, family members, and online. They observed decreases in retail advertising of menthol cigarettes, although many felt e-cigarettes and online advertising were more significant issues for their age group. Findings show a need for increased education and more comprehensive policy approaches, including addressing use of flavored e-cigarettes, online tobacco sales, and informal access, making youth access to tobacco more difficult.
Relationships of ABO and Rhesus blood groups with type 2 diabetes mellitus: a systematic review and meta-analysis

Objectives The susceptibility to type 2 diabetes mellitus (T2DM) has been linked to blood type. We aimed to characterize the relationships of the ABO and Rhesus blood groups with T2DM. Methods Literature searches were performed using the Medline, PubMed, Scopus, Cochrane, EMBASE, and Google Scholar databases to identify studies published up to 31 March 2022. The PRISMA guidelines were used for reporting. Pooled odds ratios (ORs) with 95% confidence intervals (CIs) were obtained using fixed-effects models. Results Twenty-six studies of 6870 patients with T2DM and 11,879 controls were identified. Compared with the other ABO groups, people with blood type B were at higher risk of T2DM (OR: 1.30, 95% CI: 1.20–1.41), while group O was associated with a lower risk (OR: 0.92, 95% CI: 0.86–0.98). There were no significant associations of T2DM with blood types A or AB, or Rh factor. Conclusion Individuals with blood type B are at higher risk of developing T2DM. Therefore, they should be screened for T2DM on a frequent basis and be made aware of the importance of maintaining a balanced diet and regular exercise for the prevention of obesity and T2DM. PROSPERO registration number CRD42022353945.
Physical activity and depression in Indonesian adults with stroke: A nationwide survey.

PURPOSE To examine the associations between physical activity and depressive symptoms in adults with stroke. DESIGN We conducted a cross-sectional study involving the data of 3234 adults with stroke obtained from the 2018 Basic Health Research (Riset Kesehatan Dasar, RISKESDAS). METHODS Physical activity level in metabolic equivalents-minutes per week were determined using the Global Physical Activity Questionnaire according to the World Health Organization (WHO) guidelines on physical activity and sedentary behavior recommendations. Depression was assessed using the Mini-International Neuropsychiatric Interview. Multivariate binomial logistic regression analysis was performed to examine the predictive role of physical activity for depression after adjusting for confounders. RESULTS Adults with stroke who met the WHO recommendation of physical activity were independently and significantly associated with lower odds of depression after adjustment for confounders (adjusted OR = 0.757, p = 0.017). CONCLUSIONS Performing physical activity according to the WHO recommendation is associated with a lower likelihood of depression among Indonesian adults with stroke. CLINICAL RELEVANCE Clinicians should be informed by the findings of this study and prescribe exercise interventions or plan physical activities to optimize recovery and prevent poststroke depression.
Positive Integer Solutions of the Pell Equation $x^{2}-dy^{2}=N,$ $% d\in \left\{k^{2}\pm 4,\text{}k^{2}\pm 1\right\} $ and $N\in \left\{\pm 1,\pm 4\right\}

Let $\ k$ be a natural number and $d=k^{2}\pm 4$ or $k^{2}\pm 1$. In this paper, by using continued fraction expansion of $\sqrt{d},$ we find fundamental solution of the equations $x^{2}-dy^{2}=\pm 1$ and we get all positive integer solutions of the equations $x^{2}-dy^{2}=\pm 1$ in terms of generalized Fibonacci and Lucas sequences. Moreover, we find all positive integer solutions of the equations $x^{2}-dy^{2}=\pm 4$ in terms of generalized Fibonacci and Lucas sequences. Although some of the results are well known, we think our method is elementary and different from the others.
Clinical indicators of acute deterioration in persons who reside in residential aged care facilities: A rapid review

Abstract Purpose To identify the clinical indicators of acute deterioration in residents and the factors that influence residential aged care facility staff's identification of these. Design Rapid review and narrative synthesis. Methods The WHO and Cochrane Rapid Review Methods Group recommendations guided the review processes. CINAHL, Medline, PubMed, and the Cochrane Library were searched from 2000 to January 2022. Data related to clinical indicators of deterioration were categorized using the Airway, Breathing, Circulation, Disability, Exposure assessment framework, and factors influencing detection were grouped as consumer (resident and family), aged care workforce, and organization factors. Results Twenty publications were included of which 14 informed clinical indicators; nine highlighted factors that influence staff's identification of these and three informed both. Included article were collectively below moderate quality. Most clinical indicators were grouped into the ‘Disability’ category with altered level of consciousness, behavior, and pain identified most frequently. Few studies reported more traditional indicators of deterioration used in the general population – changes in vital signs. The most common factors influencing the detection of acute deterioration were organizational and workforce‐related including resource, knowledge, and confidence deficits. Conclusion Findings suggest subtle changes in resident's health status, rather than focusing primarily on physiologic parameters used in early warning tools for acute care settings, should be recognized and considered in the design of early warning tools for residential aged care facilities. Clinical Relevance Early warning tools sensitive to the unique needs of residents and support for aged care facility staff are recommended to improve the capacity of aged care facility care staff to identify and manage acute deterioration early to avoid hospitalization.
Anomaly Detection and Correction of Optimizing Autonomous Systems With Inverse Reinforcement Learning

This article considers autonomous systems whose behaviors seek to optimize an objective function. This goes beyond standard applications of condition-based maintenance, which seeks to detect faults or failures in nonoptimizing systems. Normal agents optimize a known accepted objective function, whereas abnormal or misbehaving agents may optimize a renegade objective that does not conform to the accepted one. We provide a unified framework for anomaly detection and correction in optimizing autonomous systems described by differential equations using inverse reinforcement learning (RL). We first define several types of anomalies and false alarms, including noise anomaly, objective function anomaly, intention (control gain) anomaly, abnormal behaviors, noise-anomaly false alarms, and objective false alarms. We then propose model-free inverse RL algorithms to reconstruct the objective functions and intentions for given system behaviors. The inverse RL procedure for anomaly detection and correction has the training phase, detection phase, and correction phase. First, inverse RL in the training phase infers the objective function and intention of the normal behavior system using offline stored data. Second, in the detection phase, inverse RL infers the objective function and intention for online observed test system behaviors using online observation data. They are then compared with that of the nominal system to identify anomalies. Third, correction is executed for the anomalous system to learn the normal objective and intention. Simulations and experiments on a quadrotor unmanned aerial vehicle (UAV) verify the proposed methods.
The impact of dolutegravir‐based combination antiretroviral therapy on the spermatozoa and fertility parameters of men living with human immunodeficiency virus

The factors responsible for this reported fertility decline among human immunodeficiency virus (HIV) positive men is yet to be determined. This study is aimed at investigating the impact of HIV or combination antiretroviral therapy (cART) on sperm cells, reproductive hormones, oxidative stress markers, apoptosis, and sperm DNA fragmentation of men living with HIV. Twenty‐one men living with HIV gave their written informed consent to participate in this study. Only 11 of the participants successfully donated blood and semen before and after 3 months of their treatment with cART. Semen, reproductive hormones, oxidative stress biomarkers, and DNA fragmentation were analysed. Data were subjected to Wilcoxon matched pairs signed rank test (ethical approval: CMUL/HREC/09/19/614). There was a significant decrease in viral load of HIV (p < 0.01), and a marked increase in progressive and total sperm motility. Total sperm count, morphology, and vitality had no significant change after 3 months of treatment with cART however, there was a significant increase (p < 0.05) in testosterone from 2.48 to 3.68 ng/ml, but luteinizing hormone decreased significantly (p < 0.05) from 9.6 to 6.5 mIU/ml. In addition, sperm DNA fragmentation increased significantly (p < 0.01). Conversely, viral load, and catalase decreased significantly, but no significant difference in malondialdehyde. This study showed that HIV depleted testosterone and impaired sperm motility which may negatively affect the fertility potential of men living with HIV. It also showed that adherence to cART (a combination of tenofovir, lamivudine, and dolutegravir) reduces the viral load and reverses the deleterious effects of cART albeit, cART appears to be toxic at subcellular spermatogenic levels.
Dose–response effect of L-theanine on psychomotor speed, sustained attention, and inhibitory control: a double-blind, placebo-controlled, crossover study

ABSTRACT Background: L-theanine is a non-protein-forming amino acid found in tea. Previous research shows high doses (100–400 mg) of L-theanine enhances attention, mainly by reducing mind wandering and distracter processing. We hypothesized that these indirect mechanisms could significantly improve the performance of low-level attentional tasks, whereas the relative contribution could be less in complex attentional tasks that require active, higher-order processing of target stimuli. Methods: To test this hypothesis, we conducted a double-blind, placebo-controlled, counterbalanced, four-way crossover study in 32 healthy young adults, where we compared the effects of three doses of L-theanine (100, 200 and 400 mg) with a placebo (distilled water), administered before and 50 min after dosing, on three attentional tasks from the Cambridge Neuropsychological Test Automated Battery [viz. Reaction Time (RTI)–visuomotor speed, Rapid Visual Information Processing (RVP)–sustained attention, and Stop Signal Task (SST)–inhibitory control]. Results were analyzed in dose × time repeated measures ANOVA models, with subsequent pairwise comparisons. Results: Active doses significantly improved reaction times in the RTI (100–200 mg) and RVP (200–400 mg) tasks from baseline (p < 0.05), but once controlled for the change-from-baseline caused by placebo, only the RTI simple reaction times showed significant improvements, following 100 mg (Δ = 16.3 ms, p = 0.009) and 200 mg (Δ = 16.9 ms, p = 0.009) of L-theanine. Conclusions: Consistent with our hypothesis, these findings suggest that L-theanine significantly improves attention in simple visuomotor tasks, but not in more complex sustained attention tasks, or executive control tasks that require top-down inhibition of pre-active responses.
Association of service use with subjective oral health indicators in a freedom of choice pilot

A freedom of choice pilot provided access to private oral health care services without queuing and with fixed public service‐fees for participants in Tampere region, Finland in 2018–2019. The aim of this study was to investigate how use of oral health care services differed by demographics, socioeconomic status, dental fear, and self‐reported oral health in this pilot.
Analysis of HIV latent infection model with multiple infection stages and different drug classes

Latently infected CD T cells represent one of the major obstacles to HIV eradication even after receiving prolonged highly active anti-retroviral therapy (HAART). Long-term use of HAART causes the emergence of drug-resistant virus which is then involved in HIV transmission. In this paper, we develop mathematical HIV models with staged disease progression by incorporating entry inhibitor and latently infected cells. We find that entry inhibitor has the same effect as protease inhibitor on the model dynamics and therefore would benefit HIV patients who developed resistance to many of current anti-HIV medications. Numerical simulations illustrate the theoretical results and show that the virus and latently infected cells reach an infected steady state in the absence of treatment and are eliminated under treatment whereas the model including homeostatic proliferation of latently infected cells maintains the virus at low level during suppressive treatment. Therefore, complete cure of HIV needs complete eradication of latent reservoirs.
NEAR-INFRARED VARIABILITY IN YOUNG STARS IN CYGNUS OB7

We present the first results from a 124 night J, H, K near-infrared monitoring campaign of the dark cloud L 1003 in Cygnus OB7, an active star-forming region. Using three seasons of UKIRT observations spanning 1.5 years, we obtained high-quality photometry on 9200 stars down to J = 17 mag, with photometric uncertainty better than 0.04 mag. On the basis of near-infrared excesses from disks, we identify 30 pre-main-sequence stars, including 24 which are newly discovered. We analyze those stars and find that the NIR excesses are significantly variable. All 9200 stars were monitored for photometric variability; among the field star population, ∼160 exhibited near-infrared variability (1.7% of the sample). Of the 30 young stellar objects (YSOs), 28 of them (93%) are variable at a significant level. Of the 30 YSOs, twenty-five have near-infrared excess consistent with simple disk-plus-star classical T Tauri models. Nine of these (36%) drift in color space over the course of these observations and/or since Two Micron All Sky Survey observations such that they cross the boundary defining the NIR excess criteria; effectively, they have a transient near-infrared excess. Thus, time-series JHK observations can be used to obtain a more complete sample of disk-bearing stars than single-epoch JHK observations. About half of the YSOs have color-space variations parallel to either the classical T Tauri star locus or a hybrid track which includes the dust reddening trajectory. This indicates that the NIR variability in YSOs that possess accretion disks arises from a combination of variable extinction and changes in the inner accretion disk: either in accretion rate, central hole size, and/or the inclination of the inner disk. While some variability may be due to stellar rotation, the level of variability on the individual stars can exceed a magnitude. This is a strong empirical suggestion that protoplanetary disks are quite dynamic and exhibit more complex activity on short timescales than is attributable to rotation alone or captured in static disk models.
Environmental risk factors for inflammatory bowel disease

Abstract Inflammatory bowel disease (IBD) is a chronic, progressive immune‐mediated inflammatory condition of the gastrointestinal tract. Environmental risk factors play a role in developing either type of IBD, Crohn's disease and ulcerative colitis; although the exact mechanism is still unknown. Herein, we review environmental risks from early life exposures, lifestyle and hygiene, vaccinations, surgeries, exposure to drugs and gastrointestinal pathogens that may increase the risk of developing IBD.
MAGNETOHYDRODYNAMIC NUMERICAL SIMULATION OF WIND PRODUCTION FROM HOT ACCRETION FLOWS AROUND BLACK HOLES AT VERY LARGE RADII

Numerical simulations of hot accretion flows around black holes have shown the existence of strong wind. Those works focused only on the region close to the black hole and thus it is unknown whether or where the wind production stops at large radii. To address this question, we have recently performed hydrodynamic (HD) simulations by taking into account the gravitational potential of both the black hole and the nuclear star cluster. The latter is assumed to be proportional to , with σ being the velocity dispersion of stars and r the distance from the center of the galaxy. It was found that when the gravity is dominated by nuclear stars, i.e., outside a radius , winds can no longer be produced. That work, however, neglects the magnetic field, which is believed to play a crucial dynamical role in the accretion and thus must be taken into account. In this paper, we revisit this problem by performing magnetohydrodynamic (MHD) simulations. We confirm the result of our previous paper, namely that wind cannot be produced in the region . Our result, combined with recent results of Yuan et al., indicates that the formula describing the mass flux of wind, , can only be applied to the region where the black hole potential is dominant. Here is the mass accretion rate at the black hole horizon and the value of RA is similar to the Bondi radius.