Miracle-dz/UniFAR-FTUs huggingface dataset:
Mathematic Creative Thinking Processes Through Mind-Mapping Based Aptitude Treatment Interaction Learning Model: A Mixed Method Study

This study aims 1) to determine the effectiveness of the Mind-Mapping based Aptitude Treatment Interaction model towards creative thinking and 2) to explain the mathematical creative thinking process based on the creative level. The number of participants was 26 students who took the Multivariable Calculus course in the odd semester of 2020/2021. This research used the mixed-concurrent embedded method. The data collection techniques were validation, observation, creative thinking tests, and interviews. The results showed that 1) the Mind-Mapping based Aptitude Treatment Interaction model was effective in developing creative thinking, as indicated by the average creative thinking score of the experimental class, which was higher than the control class and 2) the characteristics of students mathematical creative thinking process varied following the creative thinking levels. The students mathematical creative thinking level consists of not creative (CTL 0), less creative (CTL 1), quite creative (CTL 2), creative (CTL 3), and very creative (CTL 4). Students at the CTL 2, CTL 3, and CTL 4 can meet the aspects of fluency, flexibility, and originality.
Finite time blow-up for quasilinear wave equations with nonlinear dissipation

"In this paper we consider a class of quasilinear wave equations $$u_{tt}-\Delta_{\alpha} u-\omega_1\Delta u_t-\omega_2\Delta_{\beta}u_t+\mu\vert u_t\vert^{m-2}u_t=\vert u\vert^{p-2}u,$$ associated with initial and Dirichlet boundary conditions. Under certain conditions on $\alpha,\beta,m,p$, we show that any solution with positive initial energy, blows up in finite time. Furthermore, a lower bound for the blow-up time will be given. "
Mitophagy and endoplasmic reticulum‐phagy accelerated by a p62 ZZ ligand alleviates paracetamol‐induced hepatotoxicity

Paracetamol (acetaminophen)‐induced hepatotoxicity is the leading cause of drug‐induced liver injury worldwide. Autophagy is a degradative process by which various cargoes are collected by the autophagic receptors such as p62/SQSTM1/Sequestosome‐1 for lysosomal degradation. Here, we investigated the protective role of p62‐dependent autophagy in paracetamol‐induced liver injury.
Use of a spherical concave reflector for jet‐noise‐source distribution diagnosis

An account on the development of a directional microphone system for jet‐noise‐source strength distribution measurements is given. The system selected is based on the imaging principle of a spherical concave reflector. As expected, the system is diffraction limited; a loss of resolution results. A special technique is discussed to recover the axial‐source strength distribution from the diffracted data. Sample experiments are presented to show the successful application of such a system for jet noise measurements.Subject Classification: [43]28.65; [43]50.55; [43]85.62.
Theory and simulation of rotational shear stabilization of turbulence

Numerical simulations of ion temperature gradient (ITG) mode transport with gyrofluid flux tube codes first lead to the rule that the turbulence is quenched when the critical E×B rotational shear rate γE−crit exceeds the maximum of ballooning mode growth rates γ0 without E×B shear [Waltz, Kerbel, and Milovich, Phys. Plasmas 1, 2229 (1994)]. The present work revisits the flux tube simulations reformulated in terms of Floquet ballooning modes which convect in the ballooning mode angle. This new formulation avoids linearly unstable “box modes” from discretizing in the ballooning angle and illustrates the true nonlinear nature of the stabilization in toroidal geometry. The linear eigenmodes can be linearly stable at small E×B shear rates, yet Floquet mode convective amplification allows turbulence to persist unless the critical shear rate is exceeded. The flux tube simulations and the γE−crit≈γ0 quench rule are valid only at vanishing relative gyroradius. Modifications and limits of validity on the quench rul.
Fatal falls from height: Pattern of injuries and effect of level of fall

In both clinical and forensic medicine, injuries resulting from falls establish a non-negligible ratio of patients and post-mortem examinations. Aim: The aim of this study is to assess the pattern of injuries and effect of level of fall among cases of fatal falls from height admitted to Menoufia University Hospital from the first of June 2016 to the end of May 2021. Patients & methods: This retrospective study data was retrieved from patients' medical reports and from patients' hospital records using a special questionnaire prepared for this purpose. Data were collected including socio-demographic data, fall characteristics (time and place of occurrence), the height of fall (fall height was classified into two categories: high (≥ 6 meter and low < 6meter), circumstances, injury pattern (site and type of injuries), duration of survival, level of consciousness according to Glasgow coma scale and possible cause of death. Results: The most represented age group was 18-<40years (41.5%) . Most of the cases were males (73.6%), accidental (98.1%), fell from ≥6 meters (56.6%), occurred at home (62.3%), at daytime (77.4), and 58.5% of cases showed injuries at multiple anatomical regions in the body. The level of fall significantly affected survival duration and types of chest and abdominal injuries. Central nervous system impairment was the cause of death in 73.6% of cases. Most patients (71.7%) had a Glasgow coma scale below 8. Conclusion : most cases were accidental, males, occurred at home, with multiple injuries. The level of fall significantly affected survival duration and types of chest and abdominal injuries. Recommendations: Necessary precautions to prevent accidental falls and safety measures for construction workers and window cleaners are mandatory.
HCV Infection and Liver Cirrhosis Are Associated with a Less-Favorable Serum Cholesteryl Ester Profile Which Improves through the Successful Treatment of HCV

Background: Infection with hepatitis C virus (HCV) lowers serum cholesterol levels, which rapidly recover during therapy with direct-acting antivirals (DAAs). Serum cholesterol is also reduced in patients with liver cirrhosis. Studies investigating serum cholesterol in patients with chronic liver diseases are generally based on enzymatic assays providing total cholesterol levels. Hence, these studies do not account for the individual cholesteryl ester (CE) species, which have different properties according to acyl chain length and desaturation. Methods: Free cholesterol (FC) and 15 CE species were quantified by flow injection analysis high-resolution Fourier Transform mass spectrometry (FIA-FTMS) in the serum of 178 patients with chronic HCV before therapy and during treatment with DAAs. Results: Serum CEs were low in HCV patients with liver cirrhosis and, compared to patients without cirrhosis, proportions of CE 16:0 and 16:1 were higher whereas % CE 20:4 and 20:5 were reduced. FC levels were unchanged, and the CE/FC ratio was consequently low in cirrhosis. FC and CEs did not correlate with viral load. Four CE species were reduced in genotype 3 compared to genotype 1-infected patients. During DAA therapy, 9 of the 15 measured CE species, and the CE/FC ratio, increased. Relative to total CE levels, % CE 16:0 declined and % CE 18:3 was higher at therapy end. At this time, % CE 14:0, 16:0 and 16:1 were higher and % CE 20:4 and 22:6 were lower in the cirrhosis than the non-cirrhosis patients. Viral genotype associated changes of CEs disappeared at therapy end. Conclusions: The serum CE composition differs between patients with and without liver cirrhosis, and changes through the efficient elimination of HCV. Overall, HCV infection and cirrhosis are associated with a higher proportion of CE species with a lower number of carbon atoms and double bonds, reflecting a less-favorable CE profile.
JAMSNet: A Remote Pulse Extraction Network Based on Joint Attention and Multi-Scale Fusion

Remote photoplethysmography (rPPG) has been an active research topic in recent years. While most existing methods are focusing on eliminating motion artifacts in the raw traces obtained from single-scale region-of-interest (ROI), it is worth noting that there are some noise signals that cannot be effectively separated in single-scale space but can be separated more easily in multi-scale space. In this paper, we analyze the distribution of pulse signal and motion artifacts in different layers of a Gaussian pyramid. We propose a method that combines multi-scale analysis and neural network for pulse extraction in different scales, and a layer-wise attention mechanism to adaptively fuse the features according to signal strength. In addition, we propose spatial-temporal joint attention module and channel-temporal joint attention module to learn and exaggerate pulse features in the joint spaces, respectively. The proposed remote pulse extraction network is called Joint Attention and Multi-Scale fusion Network (JAMSNet). Extensive experiments have been conducted on two publicly available datasets and one self-collected dataset. The results show that the proposed JAMSNet shows better performance than state-of-the-art methods.
The amplitudes and phases of tidal constituents from Harmonic Analysis at two stations in the Gaspar Strait of Bangka Belitung

The waters of the Bangka Belitung islands are shallow waters that are affected by tides. The tides in these waters originate from the propagation of the Natuna and Java Seas, so they have unique characteristics. This study aims to analyze the amplitude and phase difference at 2 stations representing Bangka and Belitung Islands with the final output of LAT and HAT information as marine cadastral recommendations at Tanjung Pesona and Tanjung Tinggi stations and safe depths for ports in PPN Sungailiat and PPN Tanjung Pandan. Tidal data for 1 year with time intervals of 1 hour in 2015 were used to extract the harmonic components to determine the type of tide and calculate the tidal level at each station. The results obtained are 19 harmonic components with a diurnal tide type. The water level at Tanjung Pesona is higher than the high Tanjung, which is described by tidal levels with HAT 2.64 and 1.72 m. Safe depth of harbor pond. In the LAT condition (lowest recess), the water level at Tanjung Pesona station is above the Sungailiat PPN pool's maximum depth; on the other hand, the Tanjung Pandan PPN LAT is 0.44 m below the maximum depth of the port pool.Key Word: Bangka Belitung, chart datum, LAT, HAT, tidal level
A non-standard branch and bound method for the Hamiltonian cycle problem

In this note, we consider an embedding of a Hamiltonian cycle problem in a Markov decision process (MDP). We propose a branch and bound type method based on the frequency polytope resulting from this embedding. Among the special features of the proposed scheme are the properties that: (i) a three-way branching is the biggest that can occur, (ii) no integer-valued variable is required, and (iii), the size of the LPs solved at the nodes of the branch and bound tree can only decrease as one moves down the tree. We hope that this note will encourage researchers in combinatorial optimization to experiment with the Markov decision process embedding as a basis for new algorithmic procedures.
Programmed Cell Death-Ligand 1 in Head and Neck Squamous Cell Carcinoma: Molecular Insights, Preclinical and Clinical Data, and Therapies

Aberrant expression of the programmed cell death protein ligand 1 (PD-L1) constitutes one of the main immune evasion mechanisms of cancer cells. The approval of drugs against the PD-1-PD-L1 axis has given new impetus to the chemo-therapy of many malignancies. We performed a literature review from 1992 to August 2022, summarizing evidence regarding molecular structures, physiological and pathological roles, mechanisms of PD-L1 overexpression, and immunotherapy evasion. Furthermore, we summarized the studies concerning head and neck squamous cell carcinomas (HNSCC) immunotherapy and the prospects for improving the associated outcomes, such as identifying treatment response biomarkers, new pharmacological combinations, and new molecules. PD-L1 overexpression can occur via four mechanisms: genetic modifications; inflammatory signaling; oncogenic pathways; microRNA or protein-level regulation. Four molecular mechanisms of resistance to immunotherapy have been identified: tumor cell adaptation; changes in T-cell function or proliferation; alterations of the tumor microenvironment; alternative immunological checkpoints. Immunotherapy was indeed shown to be superior to traditional chemotherapy in locally advanced/recurrent/metastatic HNSCC treatments.
The knowledge of Schizophrenia among health- related students in Umm Al-Qura University: A cross sectional survey

Background: Schizophrenia is a mental psychotic disorder where the patient may experience hallucinations or disorganized speech with the likely correlation with negative symptoms. This study aimed to estimate the knowledge, awareness and attitude of schizophrenia among health-related students at Umm Al-Qura University in Saudi Arabia. Methods: A cross sectional study was conducted among interns and undergraduate students from different health related specialties at Umm Al-Qura University. Data is collected by an online questionnaire distributed via various social media platforms. Result: Out of 830 students, the overall response about previous hearing of schizophrenia was very positive, 85.1%. Unexpectedly, only a minority of students reported a good level of knowledge, 4.46%. In opposition, most students documented a poor level of understanding and knowledge, 53.98%. Students of college of medicine significantly correspond with the level of knowledge (P-value, 0.008). Further, students from the second academic year showed significant difference with a moderate level of knowledge (P-value, 0.013). In contrast students from the third year showed a significant association with a poor level of knowledge (P-value, 0.013). Conclusion: This study finds out that most students have an insufficient understanding of schizophrenia, a demand for further investigation among Saudi Universities. Additionally, this study found an incidental high level of students with a history of schizophrenia, which recommended screening of schizophrenia among students for early detection.
Effect of Non-Monetary Rewards on Employees’ Performance in Mount Meru Referral Hospital in Arusha, Tanzania

The purpose of the study was to examine the effect of non-monetary rewards on employees’ performance in Mount Meru Referral Hospital in Arusha, Tanzania. The sequential parallel design was employed to carry out the study. The target population was 355 while the sample size was 188 which included 8 managerial workers and 180 non-managerial employees of the hospital. Questionnaire and interview guide were used for data collection. The quantitative data was analyzed using both descriptive and inferential statistics while the qualitative data was thematically analyzed. The study established that non-monetary rewards such as employee recognition, training, development, employee independence and flexible work schedules have a positive effect on the employees’ performance. The practice of flexible working schedules currently in place in the hospital needs to be retained for effective job performance to be realized. The management of the hospital should get employees trained and re-trained so as to enhance their performance in terms of service delivery to patients.
Structure-oriented singular value decomposition for random noise attenuation of seismic data

Singular value decomposition (SVD) can be used both globally and locally to remove random noise in order to improve the signal-to-noise ratio (SNR) of seismic data. However, it can only be applied to seismic data with simple structure such that there is only one dip component in each processing window. We introduce a novel denoising approach that utilizes a structure-oriented SVD, and this approach can enhance seismic reflections with continuous slopes. We create a third dimension for a 2D seismic profile by using the plane-wave prediction operator to predict each trace from its neighbour traces and apply SVD along this dimension. The added dimension is equivalent to flattening the seismic reflections within a neighbouring window. The third dimension is then averaged to decrease the dimension. We use two synthetic examples with different complexities and one field data example to demonstrate the performance of the proposed structure-oriented SVD. Compared with global and local SVDs, and f–x deconvolution, the structure-oriented SVD can obtain much clearer reflections and preserve more useful energy.
Preoperative Vitamin Supplemental Therapy might improve Postoperative Outcome of CABG Surgery Patients

Objectives: The effect of preoperative vitamin supplemental therapy (VST) on serum levels of vitamin D (VD), interleukin-6 (IL-6), high-sensitivity C-reactive protein (hsCRP), malonaldehyde (MDA), and superoxide dismutase (SOD), and on outcomes of patients undergoing coronary artery bypass graft (CABG) especially the incidence of postoperative atrial fibrillation (POAF). Patients & Methods: 124 patients scheduled for elective on-pump isolated CABG surgery were clinically evaluated. Three blood samples (S1-S3); before and after VST and after aortic declamping for estimation of serum levels of 25-hydroxy VD, IL-6, hsCRP, MDA, and SOD. Patients were randomly divided into the Control group (Group C) that did not receive VST and the Study group (Group S) that received VST for four weeks. Study outcomes included POAF incidence, the change of serum levels of estimated variables in S2 and S3 concerning the S1 sample, and the relation between receiving VST and these changes. Results: Amount of chest tube drainage, the incidence of POAF and the total duration of PO hospital stay were significantly less in Group S than in Group C. VST significantly reduced serum MDA and hsCRP levels with a significantly elevated serum SOD levels in S2 than S1 samples. Preoperative VST is negative, while prolonged cardiopulmonary bypass time, high serum levels of IL-6 and hsCRP, and low serum levels of SOD in the S3 samples as significant positive predictors for POAF development. Conclusion : Reduced serum inflammatory cytokines' levels with improved levels of SOD by preoperative VST are significant predictors for decreased POAF incidence and improved CABG outcome.
Effects of Taxifolin in Spontaneously Hypertensive Rats with a Focus on Erythrocyte Quality

Oxidative stress and multiple erythrocyte abnormalities have been observed in hypertension. We focused on the effects of angiotensin-converting enzyme 2 (ACE2) inhibition by MLN-4760 inhibitor on angiotensin peptides, oxidative stress parameters, and selected erythrocyte quality markers in spontaneously hypertensive rats (SHR). We also investigated the potential effects of polyphenolic antioxidant taxifolin when applied in vivo and in vitro following its incubation with erythrocytes. SHRs were divided into four groups: control, taxifolin-treated, MLN-4760-treated, and MLN-4760 with taxifolin. MLN-4760 administration increased the blood pressure rise independent of taxifolin treatment, whereas taxifolin decreased it in control SHRs. Body weight gain was also higher in ACE2-inhibited animals and normalized after taxifolin treatment. However, taxifolin did not induce any change in angiotensin peptide concentrations nor a clear antioxidant effect. We documented an increase in Na,K-ATPase enzyme activity in erythrocyte membranes of ACE2-inhibited SHRs after taxifolin treatment. In conclusion, ACE2 inhibition deteriorated some selected RBC properties in SHRs. Although taxifolin treatment did not improve oxidative stress markers, our data confirmed the blood pressure-lowering potential, anti-obesogenic effect, and some “erythroprotective” effects of this compound in both control and ACE2-inhibited SHRs. In vitro investigations documenting different effects of taxifolin on erythrocyte properties from control and ACE2-inhibited SHRs accentuated the irreplaceability of in vivo studies.
The constrained interpolation profile method for multiphase analysis

Abstract We present a review of the constrained interpolation profile (CIP) method that is known as a general numerical solver for solid, liquid, gas, and plasmas. This method is a kind of semi-Lagrangian scheme and has been extended to treat incompressible flow in the framework of compressible fluid. Since it uses primitive Euler representation, it is suitable for multiphase analysis. The recent version of this method guarantees the exact mass conservation even in the framework of a semi-Lagrangian scheme. We provide a comprehensive review of the strategy of the CIP method, which has a compact support and subcell resolution, including a front-capturing algorithm with functional transformation, a pressure-based algorithm, and other miscellaneous physics such as the elastic–plastic effect and surface tension. Some practical applications are also reviewed, such as milk crown or coronet, laser-induced melting, and turbulent mixing layer of liquid–gas interface.
COVID-19 among Rheumatoid Arthritis Patients on ‎Immunosuppressive Therapy During the First Wave of the COVID-‎‎19 Pandemic: a Prospective Comparative Study ‎

be recruited into three groups: rheumatoid arthritis (RA) patients; rheumatoid arthritis with COVID-19 patients (RA-COVID); and a COVID-19 (COVID-19) group. Results: the mean age of the studied group was 50 years old. The three studied groups showed no statistically significant difference (p > 0.05) as regards age, sex, level of education, and marital status. But there was a statistically significant difference between groups regarding occupation and special habits in the form of hashish smoking. There was no marked difference in COVID-19 symptoms between group II and group III. The mean of the Modified Health Assessment Questionnaire (MHAQ) was 5.5 in RA group versus 8 in RA-COVID-19 group ,with statistically significant difference between group I and II as regard DAS28. The duration from being diagnosed with COVID-19 till recovery was significantly higher in RA-COVID-19 cases compared to COVID-19. RA-COVI-19 group did tend toward higher hospital admission rates (OR 0.81; 95% CI 0.35-0.88; p = 0.03). Conclusion: COVID-19 is accompanied by non-significant worsening of symptoms in RA patients on DMARDs, except the admission rates. More research into expanding cases is required .
Bulk Decay of Chlorine in Water Distribution Systems

Mathematical models of chlorine concentration in water distribution systems require the bulk decay coefficient to be quantified. The coefficient needs to be determined with respect to independent variables if models are to maintain their predictive capability as seasonal and water treatment operational changes occur. Reported herein are experiments undertaken to determine the functional dependence of the bulk-free, chlorine decay rate coefficient on total organic carbon concentration, initial chlorine concentration, temperature, and the number of rechlorinations. The resulting equation gives satisfactory results during annual cycles and the introduction of granular activated carbon treatment at a water treatment plant.
Line narrowing in a single-mode injection laser due to external optical feedback

The effect of external optical feedback on the linewidth of a single-mode injection laser is considered theoretically. A set of three rate equations with Langevin noise sources is used to obtain the power spectrum. If the high-frequency structure in the power spectrum is ignored, the line shape is Lorentzian and exhibits broadening or narrowing depending on the external-cavity phase shift. Particular attention is paid to the line narrowing after including the effect of carrrier-induced index changes.