Miracle-dz/UniFAR-FTUs huggingface dataset:
Outcome of surgical resection of de quervain’s stenosing tenosynovitis

Introduction: It is thought that repetitive and forceful manual work with wrist deviated to ulnar wards and thumb abducted and extended may lead to de Quervain’s tenosynovitis. There is a lot of treatment option both operative and non-operative for this condition. However, surgical decompression is considered when conservatives measures failed after tried for 3-6 months. But there are some complications such as neural adhesion or neuroma formation, subluxation of the volar tendon, scar hypertrophy, radial sensory nerve injury, reflex sympathetic dystrophy, infection, etc. Materials and Methods: The study was an interventional type of prospective study done at Kurmitola General Hospital from September 2017 to July 2019. A total of 31 patients of de Quervain’s tenosynovitis were included in the study precisely following inclusion and exclusion criteria. Among them, 2 patients could not be followed-up. Results: Two (6.9%) patients had not improved after 1 year of follow-up. Rest 27 (93.1%) cases were cured as there were insignificant pain or tenderness, below 4 VAS score and negative Finkelstein test. Preoperative VAS score was reduced from 8.1 ± 1.29 to 1.41 ± 2.23 at 1 month, 1.24 ± 2.15 at 6 months, and 1.10 ± 2.26 at 12-month follow-up. Functional outcomes measured using Quick DASH were also reduced significantly. Preoperative Quick DASH score was 75.39 ± 14.27 which was reduced to 16.85 ± 18.26 at 1 month, 13.56 ± 20.42 at 6 months and 15.05 ± 22.24 at 12-month follow-up. One patient developed an infection and cured with an antibiotic. Two patients had tendon subluxation after the operation where 1 cured and others had some problems. No other complication noted. Conclusion: The findings in our study showed that most of the patients were completely relieved from de Quervain’s tenosynovitis with very few complications. However, there was a limited follow-up. The surgical procedure was also time-consuming as done at OT with proper aseptic precaution. Despite those limitations, simple surgical resection in de Quervain’s tenosynovitis showed a very good treatment option.s.
Salvianolic acid B abolished chronic mild stress-induced depression through suppressing oxidative stress and neuro-inflammation via regulating NLRP3 inflammasome activation.

This study was framed to investigate the molecular mechanism behind the anti-depressant effect of salvianolic acid B (SB) against unpredictable chronic mild stress (CMS) induced depression rat model. Control rats received only saline without CMS exposure, whereas CMS model rats were induced to several stress (CMS) for 6 weeks. Treatment group rats were induced with CMS for 6 weeks but received either 20 or 40 mg/kg of SB or 20 mg/kg imipramine (CMS+IMP) from the 4th week to 6th week. Treatment with SB or IMP significantly ameliorated body weight, sucrose consumption rate with shorter immobility time than the control group. Also, administration with SB or IMP could reverse the hyperactivity of hypothalamic-pituitary-adrenal axis as well as decreased inflammatory cytokines with improved antioxidant status. Furthermore, the protein expression of NLRP3 (inflammasome) was markedly downregulated upon treatment with SB (both 20 and 40 mg) or IMP and thereby confirming its potent anti-depressant activity. PRACTICAL APPLICATIONS: Salvianolic acid B (SB) is a phenolic acid extracted from Salvia militiorrhiza Bunge, a popular Chinese herb, which has been prescribed for various pathological conditions. SB has been previously reported with anti-depressant activity but, the in-depth mechanism behind the anti-depressant effect of SB against CMS is still elusive. Hence, the current study was plotted to explore the in-depth mechanism behind the anti-depressant effect of SB against CMS model of depression in rats. The outcome of the current study has confirmed the anti-depressant activity by abolishing oxidative stress, and neuroinflammatory response in the hippocampus through inhibiting NLRP3 inflammasome activation. Hence, SB can be prescribed to major depression patients with standard anti-depressant agents to abolish oxidative stress, neuro-inflammatory response, and related neurological changes.
Systemic Unsustainability as a Threat to Democracy

Resilient socioeconomic unsustainability poses a threat to democracy whose importance has yet to be fully acknowledged. As the prospect of sustainability transition wanes, so does perceived legitimacy of institutions. This further limits representative institutions’ ability to take action, making democratic deepening all the more urgent. I investigate this argument through an illustrative case study, the 2017 People's Climate March. In a context of resilient unsustainability, protesters have little expectation that institutions might address the ecological crisis and this view is likely to spread. New ways of thinking about this problem and a new research agenda are needed.
Insomnia and Related Anxiety Among Medical Students

Objectives: The objectives of the current study were to determine the prevalence of insomnia among students of college of Medicine, Majmaah University, Saudi Arabia and to identify the rate of anxiety-related insomnia. Methodology: The study design was cross-sectional conducted at College of Medicine, Majmaah University. The sample size was taken as 190. Data were collected by a pre-tested questionnaire after obtaining ethics approval. Analysis of data was performed by SPSS. Results: Students with the subthreshold, moderate clinical and severe insomnia were 48.9%, 17.4% and 3.7% respectively. Thirtyfive (50.0%) of students who were insomniacs had mild anxiety. Forty-four (72.1%) and fifty-four (91.5%) students who had moderate and severe anxiety had insomnia respectively. Conclusion: The study concluded that the prevalence of insomnia among medical students, Majmaah University is high. There is a significant association between insomnia and anxiety. More than half of students are complaining of insomnia and anxiety comorbidity.
Timor-Leste population on internal migration, in the analysis of direction, flow, pathways, boundaries, and international procedures

This study aims to analyze and evaluate internal migration in the population of the country of Timor-Leste based on Ravenstain’s theory (1885) and Lee (1966) on types of internal migration with respect push to pull and factors and defining the flow, direction, path and boundaries of internal migration in municipal in the country of Timor-Leste. This study uses a quantitative approach, using the concept of lifetime migration and inter-municipal displacement. The analysis of cross tabulation between the place of birth and the place of registration at the time of the CPH-TL2015 has resulted internal migration of population of Timor-Leste first type. This research uses CSpro, and Excel, and GIS analysis tools with the amount of population internal migration is the percentage of migration rates. The results of this study have produced first type internal migration of Timor-Leste, specific forms of internal migration such as residents who have carried out lifetime migration internal with direction and flow through international boundaries and procedures.The geographic position each municipality and special for municipality of Oe-cusse as an enclave is particularly important and significantly new type of internal migration.
Fine-Grained Building Change Detection From Very High-Spatial-Resolution Remote Sensing Images Based on Deep Multitask Learning

Building change detection from very high-spatial-resolution (VHR) remote sensing images has gained increasing popularity in a variety of applications, such as urban planning and damage assessment. Detecting fine-grained “from–to” changes (change transition from one land cover type to another) of buildings from the VHR images is still challenging as multitemporal representation is complicated. Recently, fully convolutional neural networks (FCNs) have been proven to be capable of feature extraction and semantic segmentation of VHR images, but its ability in change detection is untested and unknown. In this letter, we leverage the semantic segmentation of buildings as an auxiliary source of information for the fine-grained “from–to” change detection. A deep multitask learning framework for change detection (MTL-CD) is proposed for detecting building changes from the VHR images. MTL-CD adopts the encoder–decoder architecture and solves the main task of change detection and the auxiliary tasks of semantic segmentation simultaneously. Accordingly, the change detection loss function is constrained by the auxiliary semantic segmentation tasks and enables the back-propagation of the building footprints’ detection errors for the improvement of change detection. A building change detection data set named the Guangzhou data set is also developed for model evaluation, in which the bitemporal R–G–B images were collected by airplane (2009) and unmanned aerial vehicle (UAV, 2019) with different flight heights. Experiments on the Guangzhou data set demonstrate that the MTL-CD method effectively detects fine-grained “from–to” changes and outperforms the postclassification methods and the direct change detection methods.
GENETIC VARIABILITY IN PROGENIES OF Eucalyptus grandis AND Eucalyptus urophylla FOR TOLERANCE TO HYDRIC DEFICIT

Genetic variability in progenies of Eucalyptus grandis and Eucalyptus urophylla for tolerance to hydric deficit. Information on the adaptation and genetic potential of Eucalyptus under water deficit conditions is necessary owing to the increasing cultivation of the genus in regions considered as "forest frontiers". Therefore, the present study aimed to estimate genetic variability, genotypic and phenotypic correlations, and estimated genetic gains in progenies of E. grandis and E. urophylla. Two progeny tests (TP1 and TP2) were performed in the municipality of Vila Nova dos Martirios (state of Maranhão, Brazil), in 30-month-old plants. The experiment was carried out using a randomized block design, with five replicates, nine plants/square plot, and 144 treatments in TP1 and 264 in TP2. Statistical analysis was performed and genetic parameters were estimated. Individual and within-progeny heritabilities were corrected using the kinship coefficient for eachspecies. Genetic gains were low, ranging from 0.96 to 6.39% for E. grandis and 1.62 to 5.48% for E. urophylla. The diameter at breast height (DBH) showed a higher coefficient of genetic variation compared with the other measured characteristics, suggesting a higher potential for selection. High, positive, and significant correlations were observed between DBH and height (H), indicating the possibility of obtaining gains based on a single characteristic. Heritability was considered low, thus directly influencing the selection gains, which were lower than those commonly reported in other studies. These findings provide important information for breeding programs in areas of forest expansion.
Exploring design considerations of acute care for the elderly to improve patient outcomes

Acute Care for the Elderly (ACE) is a model designed to address acutely ill elders by minimizing risks associated with hospitalization and maximizing or maintaining physical and cognitive functional levels during their stay. The ACE model incorporates four main principles into their concept, including patientand familycentered care, a prepared physical environment, a specialized interdisciplinary team, and early discharge planning. The positive impacts of ACE include improved functional status, reduced rate of hospital readmission, decreased fall rates, shorter length of stay, reduced costs, and higher patient/provider satisfaction. The purpose of this research study was to understand the ACE model of care and identify environmental design strategies that support the physical, social, and psychological well-being of patients within the ACE unit and elder-friendly design. An integrative literature review was employed to identify design elements and considerations within the ACE units and hospitals for older adults, specifically within patient rooms. Key environmental facilitators in patient rooms for older adults include privacy, accessibility, familiarity, and social interaction. Designing an ACE unit that ensures the physical, social, and psychological well-being of the older adult requires knowledge of acute illness, age-related functionality, and elements of design needed to successfully carry out the model of care.
GGE BIPLOT ANALYSIS IN WILD (PISUM SATIVUM L. SUBSP. ELATIUS AND SUBSP. SATIVUM) AND CULTIVATED PEA (PISUM SATIVUM L.) GENOTYPES IN NORTHERN AND SOUTHERN TURKEY

This research was carried out in the multiple-environment trials (MET) which one is in Bayburt (40°24'05.7"N 40°08'31.3"E) where the Black Sea geographical region located in the north of Turkey and in the Kahramanmaras (37°35'24.8"N 36°48'49.4"E) where the Mediterranean geographical region located in the south of Turkey in 2016 and 2017 years. In this investigation, 6 registered pea cultivars (Bolero, Jof, Karina, Nihal, Reyna and Utrillo) and 2 wild pea genotypes (Pisum sativum L. subsp. elatius and P. sativum L. subsp. sativum) were used. The variance analysis showed a significant difference among Location (L), genotypes (G), genotypes×locations interaction (GL), genotypes×year interaction (GY), year×location interaction (YL) (all significant at P<0.01 level) and genotype×location×year interaction (GLY) (significant at P<0.05 level) interaction in terms of seed yield. Main effect genotypes (G) is explained 24.42% of total variation. This is followed by 18.78% (L), 17.87% (YL) 7.04% (GL), 4.91% (GY), 2.71% (GLY) and 1.12% (Y), respectively. Graphs were drawn according to the results of GGE biplot analysis and yield data of genotypes were evaluated according to these graphs. In accordance with GGE biplot analysis the seed yield first principal component explained 82.81% of the total variation and second principal component explained 17.19% of the total variation.
Fuzzy Approximate Learning-Based Sliding Mode Control for Deploying Tethered Space Robot

This article proposes a hybrid control scheme synthesizing fuzzy approximate Q-iteration algorithm and discrete-time terminal-like sliding mode control for deploying tethered space robot, which is modeled as a deterministic Markov decision process. The existence of a switching condition allows FQ-iteration algorithm and terminal-like sliding surface constituting an optimal sliding mode control, and the fuzzy logic approximation is employed to improve the efficiency of optimization. Under arbitrary switching, the sliding mode reaching law works to compress the contraction of sliding surface variable. Simulation results verify the analyses on contraction of fuzzy approximate Q-iteration for optimal sliding mode control, the stability of reduced-order system yielded by the proposed discrete-time terminal-like sliding surface, and existence of switching condition.
Strategic climate policy with endogenous plant location: The role of border carbon adjustments

Carbon leakage and the relocation of rms is one of the main concerns of governments when choosing their climate policy. In a strategic trade model with endogenous plant location, we study the effect of border carbon adjustments (BCAs) on equilibrium emission taxes in a non-cooperative policy game between two asymmetric countries. To this end, we compare a No-BCA regime with a BCA regime for two scenarios: a simultaneous and a sequential game. Without BCAs, a “race to the bottom” is the only Nash equilibrium. In a Stackelberg equilibrium, a second less negative outcome may emerge, which constitutes a Pareto-improvement to all governments. In this “wise chicken equilibrium”, the Stackelberg leader gives in, letting his/her firms relocate in order to avoid the race-to-the-bottom equilibrium. With BCAs, the race-to-the-bottom in carbon taxes can be avoided in the Nash equilibrium and also in Stackelberg equilibria global emissions are reduced. We show that the country imposing BCAs is always better off, global welfare usually increases with BCAs, even though the country on which BCAs are imposed may be better worse off. We characterize those conditions.
Bandgap and Vibration Reduction of Laminated Galfenol Phononic Crystal With Shunt Circuit

It is of great significance to adjust bandgaps (BGs) of laminated Galfenol phononic crystal (PC) by using nonlinearity of Villari effect and shunt elements for effectively reducing vibration. Based on the modified constitutive equations, the effective elastic modulus, and transfer matrix method (TMM), a dynamic nonlinear model with tunable elastic modulus for the PC is established. Comparisons between the calculated and measured results show that the model can describe the changing laws of the Galfenol rod’s effective elastic modulus with frequency and shunt capacitance, and can predict nonlinearity of the rod. The effects of stress and bias field on the attenuation constant peak and cutoff frequency of Bragg BGs (BBGs) are analyzed, and the optimal and suboptimal operating points of BBGs are determined. The effects of shunt capacitance and stress on BBGs, resonant BGs (RBGs), and common BGs (CBGs) are analyzed, and it is found that larger magnetomechanical coupled factor and smaller shunt capacitance can effectively reduce vibration.
Glutamine synthetase structure‐catalysis relationship—Recent advances and applications

Glutamine synthetase is a key enzyme that exists in every living organism. It is responsible for incorporating ammonium into glutamate, generating glutamine. Research on this enzyme has grown substantially over the last decades. The recent advances in the determination of its structure, through the crystallization of novel classes of glutamine synthetase with increased resolution, greatly contributed to a shift in the glutamine synthetase research from fundamental to more applied. Here, we explore the active sites of glutamine synthetases, review the structural and catalytic roles of their active sites' ions Mg2+s, combine the information gathered from recent computational studies dedicated to unravel their catalytic mechanisms with the hypothesis raised at the beginning of the XXI century based on experimental studies, glance at the development of competitive glutamine synthetase inhibitors, and highlight the high value of these enzymes to industry, namely in the fields of agriculture and medicine.
Dosimetric Evaluation of Deep Inspiration Breath-Hold Technique for Breast Cancer Radiotherapy: A Single-Center Experience

METHODS In this study, 102 patients who underwent adjuvant RT for the treatment of breast cancer in our clinic between November 2018 and December 2019 were included. A breast and/or chest wall, and/or lymph node RT of 50 Gy in 25 fractions was planned for all patients, and an additional boost of 10 Gy in five fractions was planned for patients requiring an RT boost. The treatment plans included 3DCRT, Field in Field (FIF), IMRT and VMAT approaches.
Electric Street Car as a Clean Public Transport Alternative: A Choice Experiment Approach

Electric Street Car (ESC) has established itself as an ideal public transport system for urban agglomeration by offering better safety, minimum pollution and conservation of fossil fuel. Yet, India envisions going all-electric by 2030 by procuring electric buses (e-buses) rather than ESCs. The crucial question is, why not upgrade the existing ESC considering that the e-buses need a profound infrastructural development in India. This paper studies the potential uptake rate of ESC over e-buses using stratified sampling data from 1226 daily public transport commuters of Kolkata, the only Indian city having an operational ESCs. We identify the demographic, psychometric and socio-economic factors influencing the probabilistic uptake of ESC over e-buses using a random utility choice model. It estimates that 38% of the commuters demand ESC over e-buses given the alternatives’ comparative details. ESC can be a model electric public transport if there is an improvement in factors, like frequent availability of ESCs and technological upgradation. By promoting the ESC services over e-buses, the government can potentially save on public investment and reach a low carbon pathway cost-effectively. The findings have crucial implications in exploration of the operational feasibility of ESC in the small and medium-sized cities of developing economies like India.
Combining Ability and Heterosis for Yield and Related Traits in Chili (Capsicum annuum L.)

An experiment was conducted to study combining ability and heterosis for yield and related traits in chili during November 2015 to September 2017. The experimental material consisted of six parents and their fifteen F1’s developed by half diallel mating design. Analysis of variance for combining ability exhibited significant General and Specific Combining Ability (GCA and SCA) effects for all the characters studied. The SCA variance was higher than GCA variance for all the traits except ten fresh fruit weight, fruit length and fruit width indicating the predominance of non-additive type of gene action. The parents P1 and P6 were identified as the best general combiners and the hybrids P1×P6, P1×P4 and P2×P5 were identified as the best specific combinations for fresh fruit yield per plant and related traits. The hybrids P1×P6, P1×P4 and P3×P6 showed significant average heterosis and heterobeltiosis for fresh fruit yield per plant and its related traits. (H1/D)0.5 ratio indicated partial dominance effect of genes for all the traits. Therefore, it may be possible to take advantages of better heterotic effects to be fixed in the later generations to facilitate further selection and best specific combinations for development of the hybrid variety of chili which can help to increase the total production in Bangladesh.
Prognostic significance of poorly differentiated cluster grading system in intestinal type gastric adenocarcinoma

Aim: Gastric carcinoma is the fourth most common carcinoma worldwide. The relationships established between the tumor morphology and the prognosis have not been very effective until recent times. Poorly Differentiated Clusters (PDCs); are structures those can be easily identified in H&E sections. A new grading system based on PDC count has been studied in colorectal carcinoma; and found to be associated with prognosis. We have aimed to investigate this concept in gastric carcinoma. Material and Methods: Our study included 80 cases, consisting of 16 females and 64 males having gastric carcinoma with intestinal morphology. For each case; conventional grade, PDC grade and prognostic parameters to be applied in the study were determined, and statistically compared. Results: Significant discrepancy was found between the two grading systems. PDC tumor grades were statistically related to; median metastatic lymph node counts, metastatic lymph node ratios, lymph node stages (pN) and the presence of perineural invasion. Conclusion: In stomach carcinoma; PDC grading system was found to be related to a significant part of the expected parameters and may have a prognostic value.