Miracle-dz/UniFAR-FTUs huggingface dataset:
Causality Correlation in Aeroacoustic Experiments byMeans of Simultaneous PIV and Microphone-ArrayMeasurements

In this paper we present applications of the causality correlation technique by means of simultaneous PIV measurements in a turbulent flow and microphone-array measurements in the aeroacoustic far field of the flow. Both measurements were conducted in a synchronized manner so as to enable the calculation of the cross-correlation between the acoustic pressure and flow quantities derived from the measured velocity fluctuations. The main idea of the concept presented here is to use the coefficient matrix obtained from the aforementioned correlation to identify regularities in the near-field fluctuations that are related to the radiated sound field. The method is used for the identification of flow structures that are involved in the generation mechanism of aeroacoustic noise sources. Results for measurements on a Rod-Airfoil configuration with a strong tonal component in the acoustic far-field as well as for a cold jet with a broadband spectrum are presented.
Mechanism Analysis of Metabolic Fatty Liver on Largemouth Bass (Micropterus salmoides) Based on Integrated Lipidomics and Proteomics

Metabolic fatty liver disease caused by high-starch diet restricted the intensive and sustainable development of carnivorous fish such as largemouth bass. In this study, the combination liver proteomic and lipidomic approach was employed to investigate the key signaling pathways and identify the critical biomarkers of fatty liver in largemouth bass. Joint analysis of the correlated differential proteins and lipids revealed nine common metabolic pathways; it was determined that FABP1 were significantly up-regulated in terms of transporting more triglycerides into the liver, while ABCA1 and VDAC1 proteins were significantly down-regulated in terms of preventing the transport of lipids and cholesterol out of the liver, leading to triglyceride accumulation in hepatocyte, eventually resulting in metabolic fatty liver disease. The results indicate that FABP1, ABCA1 and VDAC1 could be potential biomarkers for treating metabolic fatty liver disease of largemouth bass.
Water-Soluble Tomato Concentrate, a Potential Antioxidant Supplement, Can Attenuate Platelet Apoptosis and Oxidative Stress in Healthy Middle-Aged and Elderly Adults: A Randomized, Double-Blinded, Crossover Clinical Trial

Increased oxidative stress and platelet apoptotic in middle-aged and elderly adults are important risk factors for atherosclerotic cardiovascular disease (ASCVD). Therefore, it is of great significance to control the oxidative stress and platelet apoptosis in middle-aged and elderly adults. Previous acute clinical trials have shown that water-soluble tomato concentrate (WSTC) from fresh tomatoes could exert antiplatelet benefits after 3 h or 7 h, but its effects on platelet apoptosis and oxidative stress are still unknown, especially in healthy middle-aged and elderly adults. This current study aimed to examine the efficacies of WSTC on platelet apoptosis and oxidative stress in healthy middle-aged and elderly adults via a randomized double-blinded placebo-controlled crossover clinical trial (10 weeks in total). A total of 52 healthy middle-aged and elderly adults completed this trial. The results showed that WSTC could increase the serum total antioxidant capacity levels (p < 0.05) and decrease the serum malondialdehyde levels (p < 0.05) after a 4-week WSTC supplementation in healthy middle-aged and elderly adults. Platelet endogenous reactive oxygen species generation (p < 0.05), mitochondrial membrane potential dissipation (p < 0.05) and phosphatidylserine exposure (p < 0.05) were attenuated. In addition, our present study also found that WSTC could inhibit platelet aggregation and activation induced by collagen or ADP after intervention (p < 0.05), while having no effects on adverse events (p > 0.05). The results suggest that WSTC can inhibit oxidative stress and its related platelet apoptosis, which may provide a basis for the primary prevention of WSTC in ASCVD.
Integrated Approach in Genomic Selection to Accelerate Genetic Gain in Sugarcane

Marker-assisted selection (MAS) has been widely used in the last few decades in plant breeding programs for the mapping and introgression of genes for economically important traits, which has enabled the development of a number of superior cultivars in different crops. In sugarcane, which is the most important source for sugar and bioethanol, marker development work was initiated long ago; however, marker-assisted breeding in sugarcane has been lagging, mainly due to its large complex genome, high levels of polyploidy and heterozygosity, varied number of chromosomes, and use of low/medium-density markers. Genomic selection (GS) is a proven technology in animal breeding and has recently been incorporated in plant breeding programs. GS is a potential tool for the rapid selection of superior genotypes and accelerating breeding cycle. However, its full potential could be realized by an integrated approach combining high-throughput phenotyping, genotyping, machine learning, and speed breeding with genomic selection. For better understanding of GS integration, we comprehensively discuss the concept of genetic gain through the breeder’s equation, GS methodology, prediction models, current status of GS in sugarcane, challenges of prediction accuracy, challenges of GS in sugarcane, integrated GS, high-throughput phenotyping (HTP), high-throughput genotyping (HTG), machine learning, and speed breeding followed by its prospective applications in sugarcane improvement.
Isolating Student, School, and Community Effects on School Weapon Carrying

Much prior research has alluded to the importance of community conditions in shaping levels of violence in around and schools. It is interesting to find, therefore, that few studies have systematically examined the effects of broader contextual characteristics (e.g., economic disadvantage) on levels of student misbehavior in schools. This research filled a part of this void in the school violence literature by using data from the National Longitudinal Study of Adolescent Health to identify whether social conditions in schools' attendance areas were statistically related to levels of student weapon carrying across a national sample of 55 high schools. Multilevel models estimated in this research revealed that levels of economic disadvantage, residential mobility, and violent crime in schools' attendance areas were unrelated to between-school variation in student weapon carrying. Similar null findings were found when examining levels of gun carrying among male students in the sample. Specifically, social conditions in schools' attendance areas were also unrelated to between-school variation in gun carrying among male students. Current findings, therefore, offer no support for the conventional wisdom that community conditions discernibly affect levels of weapon carrying in and around schools (i.e., spillover hypothesis). Consequently, current findings are unable to challenge the implementation of many school-based violence prevention programs that do not attempt to manipulate or change social conditions external to schools (i.e., individual-change interventions). Finally, the limitations of this research are thoroughly discussed in order to address how future research can further advance the systematic study of the effects of community conditions on violence in and around schools.
Determination of the Bioactive Effect of Custard Apple By-Products by In Vitro Assays

Annona cherimola fruit, known as cherimoya or custard apple, is an exotic fruit from South America but is strongly produced in Andalusia, Spain. Its by-products (seeds and peel) are recognised as important sources of antioxidants, including phenolic acids, flavonoids and procyanidins. Therefore, the aim of this study was to carry out the characterization of its phenolic composition and to in vitro evaluate the bioactivity of custard apple seed and peel. Therefore, high performance liquid chromatography coupled to mass spectrometry (HPLC-ESI-qTOF-MS) was performed in order to tentatively identify their phenolic composition. In the end, 19 compounds were identified and quantified, some of them for the first time in the custard apple matrix. Then, seed and peel total phenolic content, as well as antioxidant properties, radical scavenging capacity (O2, NO, HOCl) and inhibition of enzymes involved in different pathologies (hyaluronidase, elastase, collagenase, tyrosinase, acetylcholinesterase and xanthine oxidase), were evaluated. Although both extracts showed almost similar antioxidant capacities, custard apple seed stood out slightly more than peel (171 ± 2 vs. 130.0 ± 0.4 μmol TE/g DE, resp.), especially as ·NO scavenger (IC50 1.5 ± 0.2 vs. 11.8 ± 0.3 mg/L, resp.) and hyaluronidase inhibitor (IC50 170 ± 10 vs. 460 ± 20mg/L, resp.). Finally, the application of extracts on a real human model of platelet aggregation was performed, reporting antiaggregatory effects in agonist-promoted platelet thrombus formation. All these results show that custard apple by-products are stated as interesting sources of bioactive compounds with multiple industrial applications for the development of high-added-value products, such as functional foods, nutraceuticals and cosmeceuticals, promoting the circular bioeconomy of these by-products.
Transcriptional Characteristics Showed That miR-144-y/FOXO3 Participates in Embryonic Skin and Feather Follicle Development in Zhedong White Goose

Simple Summary Feather is one of the most valuable and economical products in goose farming and plays a crucial physiological role in birds. For avian biology and the poultry industry, it is essential to comprehend and regulate how skin and feather follicles develop during embryogenesis. This study showed that several key regulatory genes (FOXO3, CTGF, and PTCH1, among others) and miRNAs (miR-144-y) participated in the developmental process of the skin and feather follicles in Zhedong white goose. Our findings are particularly important because they will serve as a valuable resource for upcoming studies on down feathers in agricultural economic growth regarding complex molecular mechanisms and breeding techniques. Abstract Skin and feather follicle development are essential processes for goose embryonic growth. Transcriptome and next-generation sequencing (NGS) network analyses were performed to improve the genome of Zhedong White goose and discover the critical genes, miRNAs, and pathways involved in goose skin and feather follicle morphogenesis. Sequencing output generated 6,002,591,668 to 8,675,720,319 clean reads from fifteen libraries. There were 1234, 3024, 4416, and 5326 different genes showing differential expression in four stages, E10 vs. E13, E10 vs. E18, E10 vs. E23, and E10 vs. E28, respectively. The differentially expressed genes (DEGs) were found to be implicated in multiple biological processes and pathways associated with feather growth and development, such as the Wnt signaling pathway, cell adhesion molecules, ECM–receptor interaction signaling pathways, and cell cycle and DNA replication pathways, according to functional analysis. In total, 8276 DEGs were assembled into twenty gene profiles with diverse expression patterns. The reliability of transcriptome results was verified by real-time quantitative PCR by selecting seven DEGs and five miRNAs. The localization of forkhead box O3 (FOXO3), connective tissue growth factor (CTGF), protein parched homolog1 (PTCH1), and miR-144-y by in situ hybridization showed spatial-temporal expression patterns and that FOXO3 and miR-144-y have an antagonistic targeting relationship. The correlation coefficient of FOXO3 and miR-144-y was -0.948, showing a strong negative correlation. Dual-luciferase reporter assay results demonstrated that miR-144-y could bind to the expected location to suppress the expression of FOXO3, which supports that there is a targeting relationship between them. The detections in this report will provide critical insight into the complex molecular mechanisms and breeding practices underlying the developmental characteristics of skin and feather follicles in Zhedong white geese.
The Technology of the Learning Process Management Expert System in Higher Educational Institutions

The present paper considers the development of learning process management expert system in higher educational institutions, based on the ontological approach. The purpose of research is an improve the effectiveness of decision making during the management of learning processes by using intelligent management methods and modern approaches to knowledge modelling. The methodology of solving the set task is based on models and methods of knowledge representation usage, the artificial intelligence theory, expert methods of decision-making and general theoretical principles of the control theory, and the theory of decision-making. Authors conducted a qualitative analysis of the domain knowledge, which allowed distinguishing and formalizing main concepts and relations between them. Authors suggested a methodological approach to the construction of the learning process management system, which allows implementing knowledge-based approaches to the development of information systems in the domain knowledge of learning process management. Authors also developed the structure and formal description of the ontology of the learning process in higher educational institutions, which allows reusing the suggested solutions. Research results were implemented in the expert information system; they can be used in practice in learning process management in higher educational institutions.
Pulmonary Vein Isolation in Obese Compared to Non-Obese Patients: Real-Life Experience from a Large Tertiary Center

1. Introduction: Pulmonary vein isolation (PVI) is an established procedure used to achieve rhythm control in atrial fibrillation (AF). In obese patients (pts), in whom AF occurs more frequently, a reduced effectiveness of PVI has been observed. Therefore, this study’s aim was to compare the long-term efficacy of PVI between obese and non-obese patients. 2. Methods: We enrolled 111 consecutive pts with a body mass index (BMI) of >30 kg/m2 undergoing PVI from our large registry. Procedural data and outcomes were compared with a matched group of 115 non-obese PVI pts and the long-term outcomes were analyzed. 3. Results: Overall follow-up duration was 314 patient-years in the obese and 378 patient-years in the non-obese group. The follow-up rate was 71% in the obese and 76% in the non-obese group. In both groups, their AF-characteristics did not differ significantly, while known risk factors were significantly more prevalent in the obese group. Procedural characteristics were similar in both groups. During follow-up, the obese pts demonstrated significant weight loss compared to the non-obese pts, while at the same time, the overall recurrence rate during follow-up did not differ significantly between both groups (obese: 39.2% and non-obese: 43.7%). PVI related and long-term complications were comparable between both groups. In the univariate analysis, obesity was not found to be associated with an increased AF recurrence risk. 4. Conclusion: These real-life data demonstrate that obese pts may not show higher AF recurrence rates after PVI compared to pts with normal body weight. Furthermore, PVI was found to be safe and effective in obese patients; thus, a BMI alone may not be a criterion for refusal of PVI.
Genetics of High-temperature Fruit Set in the Tomato1

The genetics of high-temperature fruit set was studied with a complete diallel cross using 5 cultivars with excellent high temperature tolerance and a California cultivar lacking stigma exsertion. The cultivars differed genetically for number of flowers per cluster, percent fruit set, number of seeds per fruit and stigma exsertion. At normal and high temperatures recessive genes are associated with greater flower number and heritability for this character was high. Percent fruit set is under the control of a largely additive system with a moderate heritability at high temperature. Nonallelic gene interaction was involved in seed set and dominance components exceeded additive at both temperatures. Heritability for seed set was low at high temperature. Stigma exsertion at high temperature is controlled by partially dominant genes with a high diallel additive component and heritability. The results suggest that a scheme of selection for specific combining ability would be useful to combine the strengths of the high temperature tolerant lines with needed characters from a successful cultivar.
Historical Evolution of the Wave Resource and Energy Production off the Chilean Coast over the 20th Century

The wave energy resource in the Chilean coast shows particularly profitable characteristics for wave energy production, with relatively high mean wave power and low inter-annual resource variability. This combination is as interesting as unusual, since high energetic locations are usually also highly variable, such as the west coast of Ireland. Long-term wave resource variations are also an important aspect when designing wave energy converters (WECs), which are often neglected in resource assessment. The present paper studies the long-term resource variability of the Chilean coast, dividing the 20th century into five do-decades and analysing the variations between the different do-decades. To that end, the ERA20C reanalysis of the European Centre for Medium-Range Weather Forecasts is calibrated versus the ERA-Interim reanalysis and validated against buoy measurements collected in different points of the Chilean coast. Historical resource variations off the Chilean coast are compared to resource variations off the west coast in Ireland, showing a significantly more consistent wave resource. In addition, the impact of historical wave resource variations on a realistic WEC, similar to the Corpower device, is studied, comparing the results to those obtained off the west coast of Ireland. The annual power production off the Chilean coast is demonstrated to be remarkably more regular over the 20th century, with variations of just 1% between the different do-decades.
Emergency Contraceptive Pill Use and its Impact on Condom Utilization Among University Students: A Cross-Sectional Study

Purpose Emergency contraceptive pills (ECPs) prevent unplanned pregnancy but not sexually transmitted infections (STIs), and the practice of ECP may affect condom use. This study, therefore, aimed to assess ECP use and its impact on condom utilization among female students of private universities in Nekemte town, western Ethiopia. Methods An institution-based cross-sectional study was conducted on 400 female students in three different private universities from February 1 to 28, 2019. Study samples were selected through simple random sampling technique. Data collected from a structured self-administered questionnaire were analyzed using SPSS version 23.0. Bivariate and multivariate logistic regression were performed to determine factors associated with condom utilization, and statistical significance was set at 95% confidence interval (CI) using a p-value of <0.05 as a cutoff point. Results The response rate was 95.3% (381/400). Overall, 51.4% (196/381; 95% CI = 45.1%, 57.7%) had awareness of ECP. Besides, 186 (48.8%) students reported history of sexual intercourse, of which 115 (61.8%) have ever practiced ECP and 96 (51.6%) have ever used condom. However, only 11 (5.9%) have ever utilized ECP and condom concurrently. Use of ECPs (adjusted odds ratio (AOR) = 0.32; 95% CI = 0.164, 0.632; p = 0.001), belief that condom prevents STI (AOR = 3.17; 95% CI = 1.045, 8.646; p = 0.041) and thought that ECP does not prevent STI (AOR = 2.217; 95% CI = 1.172, 4.59; p = 0.032) had statistically significant association with condom utilization. Conclusion The practice of ECP was average, while dual method contraception use was low in the study area. History of ECP use and beliefs that ECP is not effective to prevent STI or condom protects against STI were factors associated with condom use.
Numerical investigation of nonlinear mechanical and constitutive effects on piezoelectric vibration-based energy harvesting

Abstract Vibration-based energy harvesting has the main objective to convert available environmental mechanical energy into electrical energy. Piezoelectric materials are usually employed to promote the mechanical-electrical conversion. This work deals with a numerical investigation that analyzes the influence of nonlinear effects in piezoelectric vibration-based energy harvesting. Duffing-type oscillator that can be either monostable or bistable represents mechanical nonlinearities. A quadratic constitutive electro-mechanical coupling model represents piezoelectric nonlinearities. The system performance is evaluated for different system characteristics being monitored by the input and the generated power. Numerical simulations are carried out exploring dynamical behavior of energy harvesting system evaluating different kinds of responses, including periodic and chaotic regimes.
STUDIES ON THE DEGRADABILITY OF SOME PROTEIN SOURCES IN MIXED DIETS

Three females Barki sheep with an average body of weight 45 kg were used in this study in order to evaluate the degradability of dry matter (DM), organic matter (OM) and crude protein (CP) of four protein sources. Four mixed diets supplemented with one of four protein sources; soybean meal (SBM), linseed meal (LSM) undecorticated cotton seed cake(UDCSC) or urea as protein sources. , Meat and bone meal (MBM) was added to all diet The degradability of whole diet was also studied. Roughage: concentrate ratio was 1:1 for all diets which were almost iso-caloric and iso nitrogenous. Data could be summarized as follow (p<0.05). ranged between40.66±0.25 for UDCSC and 60.43±0.16 for MBM with significant differences (p< 0.05).
Chitosan-Enriched Salicylic Acid Nanoparticles Enhanced Anthocyanin Content in Grape (Vitis vinifera L. cv. Red Sultana) Berries

Given the effects of salicylic acid (SA) on enhancing the phenolic compounds, flavonoids, and especially anthocyanins at higher doses in grapes as well as some toxic effects of SA at higher doses, the use of nano-carriers and nano-forms could assist SA in enhancing the accumulation of these compounds while reducing its toxic activity. Chitosan (CTS) has gained attention as a safe transporter and control releaser for a variety of chemicals, particularly in the agriculture industry. In this regard, the nano-form combination of SA and CTS (CTS-SA NPs) could boost the effectiveness of SA, particularly at lower dosages. Therefore, in the present study, SA (10, 20 mM), CTS (0.1%), and CTS-SA NPs (10, 20 mM) were applied on grape (Vitis vinifera L.) berries cv. Red Sultana at the pre-véraison stage to evaluate their actions on phenolic compounds, particularly anthocyanins. The CTS-SA NPs treatments provided the highest results in terms of the total phenolic compounds, flavonoids (10 mM), anthocyanins (in particular oenin, the main anthocyanin of red grapes) (10 and 20 mM), and PAL enzyme activity (20 mM). In conclusion, the CTS-SA NPs could be applied as a potential effective elicitor for phenolics, particularly anthocyanin enhancement of grape berries at pre- véraison stage with synergistic effects between SA and CTS in nano-forms predominantly at lower doses.