Miracle-dz/UniFAR-FTUs huggingface dataset:
T helper 17 cells and Regulatory T cells in Pulmonary Sarcoidosis : It takes two to tangle

markdownabstractSarcoidosis is an intriguingly complex immunological disorder. It is characterized by the formation of non-necrotizing granulomas that are most commonly found in the mediastinal lymph nodes and lungs of patients. Gaps in knowledge on sarcoidosis disease etiology and determinants of disease course have thus far impeded rational decisions on ‘Who, When and How’ to treat. The mainstay of sarcoidosis therapy remains immunosuppressive, using relatively high doses of systemic prednisone. However, although often effective, corticosteroid treatment can be accompanied by severe side effects. Detailed insight in the immunological response occurring in pulmonary sarcoidosis patients can help find determinants of disease etiology and disease course, which can yield new therapeutic targets. Therefore, the first aim of this thesis is to further unravel the immune-related pathogenesis of pulmonary sarcoidosis. The second aim is to gain insight into current prednisone treatment, in order to optimize treatment strategies to reduce side effects and increase quality of life of pulmonary sarcoidosis patients. Findings described in this thesis provide a new perspective on sarcoidosis pathogenesis, challenging long-held paradigms and exploring novel approaches to further unravel this immunological complex disease. Furthermore, a rationale is provided to evaluate the potential of certain existing therapies that are used in other autoimmune diseases for pulmonary sarcoidosis. Finally, results of this thesis lay a strong foundation for future studies that can help individualize sarcoidosis treatment and thereby increase pulmonary sarcoidosis-related quality of care and patient-related quality of life.
Biochemical and haematological profile of donkeys in the Czech and Slovak Republics: influence of age and sex

The aim of this study was to evaluate the importance of taking into account the age and sex of the donkeys while assessing individual haematological and biochemical variables. Material used for the study were blood samples collected from 112 clinically healthy donkeys (37 males and 75 females) aged from 05 to 30 years old. Selected haematological and biochemical variables were examined and the influence of sex and age was analyzed by multivariate analysis. Significant differences were found in some of biochemical and haematological variables between groups. The results of this study can be useful for appropriate clinical interpretation of laboratory results in donkeys.
Mothers' Knowledge and Traditional Practices for Management of their Feverish Children

Background:Fever is an everyday reaction to a set of situations, mainly the infection.Lack of knowledge regarding fever and febrile illness continues to be one of the most prevalent public health issues encountered by parents of young children. Traditional Practices relating to fever are numerous.It may include; touching the child's forehead for measuring body temperature, giving boiled herbs, making iced-cold water sponging or baths, and rubbing the child's body with vinegar, lemon or alcohol. Objective:Determine mothers' knowledge and traditional practices for management of their feverish children. Setting: The study was conducted at Pediatric Outpatient and Medical Departments of Sidi Salem General Hospital. Subjects: A convenience sample of 250 mothers who had feverish children under five years comprised study subjects. Tool: One tool used; Mothers' knowledge and traditional practices for management of their feverish children structured interview schedule. Results: The present study revealed that mothers'knowledgeabout fever were deficient in the majority of mothers regarding definition of fever(89.6%). In addition, incomplete knowledgementioned by more than half of mothers regarding causes of fever (78.8%), methods of measuring body temperature (60.0%) and non-Pharmacological methods for managing fever(57.6%). Concerning mothers' traditional practices, slightly more than half of mothers (52.4%) reported that they performed traditional practices for their feverish children. It was reported also that the performed practices were; using herbs, using honey, using oils, using lubkha, and uvula elevation (39.7%, 51.9%, 15.3%, 1.5%, and 44.3% respectively). All mothers (100%) who done traditional practices for their feverish children had unsatisfactory practices with total mean 20.67±10.32. Conclusion: It was concluded from this study that mothers'knowledgeregarding fever were deficient in more than half of mothers and all mothers who done traditional practices for their feverish children had unsatisfactory practices.
Effectiveness evaluation of Bacterial Species Isolated from soil in Bioremediation of Diazinon, Pirimicarb and Atrazine Pesticides

Pesticides are chemical compounds that are used to combat pests, including insects, rodents, fungi and unwanted plants (weeds). Pesticides are used in public health to fight vectors of disease, such as mosquitoes, and in agriculture, to combat pests that damage crops. By their nature, pesticides are potentially toxic to other organisms, including humans, and need to be used safely and disposed-off properly (WHO, 2019). Pesticides are applied to agricultural crops annually for pest control worldwide It is estimated that less than 1% of the total applied pesticides generally gets to the target pests and most of the pesticides remain unused and enter into the ecosystem. The ultimate sink for excessive pesticides is soil and water (Kuhad, et al., 2013). There is a vital need to remediate and clean heavily polluted soil with pesticides and pesticides International Journal of Current Microbiology and Applied Sciences ISSN: 2319-7706 Volume 9 Number 3 (2020) Journal homepage: http://www.ijcmas. com
The Effect of EFL Teachers' Stress on their Classroom Management Practices: An Investigation of Male and Female Teachers

The present study was conducted to investigate the relationship between perceived stress and behavior and instructional management in male and female foreign language teachers in cities of Mohr, Lamerd, Parsian and Asalouye. A total of 96 male (N = 58) and female (N = 38) university and high school teachers participated in the present study. All participants were randomly selected from different universities and high schools which were more accessible and accommodating for the purpose of study. Behavior and Instructional Management Scale (BIMS) developed by Wolfgang and Glikman (1986) was used to collect data about teachers’ reported classroom management practices. The Perceived Stress Scale (PSS) developed by Cohen, Kamarck, and Mermelstein (1983) was used for measuring the perception of stress. The reliability and validity of the questionnaires were found acceptable according to Cronbach’s Alpha and factor analysis. Questionnaires were administered to the teachers via emails and in person. The results obtained from the Pearson correlation analyses revealed that there was not a significant relationship between perceived stress and behavior management in both male and female teachers, reflecting the fact that high stress was unlikely to affect behavior management in both genders. For instructional management, it is likely for both male and female teachers to IJRDO Journal Of Educational Research ISSN: 2456-2947 Volume-3 | Issue-5 | May,2018 33 decrease their instructional management practices when their perceived stress is high. The implications of the findings are discussed.
Contribution of Community Health Volunteers in Immunization Uptake in Pokot South, Sub-County, Kenya

1=Department of Nursing Research, Education and Management, School of Nursing, Midwifery and Paramedical Sciences, Masinde Muliro, University of Science and Technology, Kenya 2=Department of Clinical Nursing and Health Informatics, School of Nursing, Midwifery and Paramedical Sciences, Masinde Muliro, University of Science and Technology, Kenya 3=Health Department, County Government of West Pokot Corresponding author: Samuel Kipunaa Lopar
Surgical Management of Oro-Antral Communication

Citation: Ahmed M Elmarakby. , et al. “Surgical Management of Oro-Antral Communication (Updated Review)”. EC Dental Science 19.4 (2020): 162-168. Abstract Background: Oro-antral communication is one of the most common complications during the oral surgical procedure. It can be caused by several conditions like the presence of upper molars with long divergent roots, cyst, periapical infections, also can be caused by maxillary tuberosity fracture. This complication should be managed quickly to prevent the epithelial growth and fistula formation. Factors like site contamination, time of perforation and diameter of defect are critical in treatment plan of this communication. It can be managed by several techniques like the use of platelet rich fibrin, buccal pad of fat, through several types of surgical flaps like buccal advancement flap, palatal rotation flap, transposition flap, or by tongue flap. This review is aimed to give a comprehensive view about the etiologies, diagnosis and the variable surgical management of oro-antral communication.
Trends in the profile of non hodgkins lymphoma in North and South India: a study from two tertiary care hospitals in India

Background: A number of environmental and chemical factors have been thought to been implicated in the occurrence of Non-Hodgkin’s Lymphomas (NHLs). To fill the knowledge gap in various aspect of the disease, this study was undertaken at this tertiary care centre in Delhi and Bangalore. Methods: This was a prospective observational study conducted in two defenses medical centre in India among patients of Non Hodgkins Lymphoma, registered at Command hospital Airforce Bangalore and Army Hospital (Research and Referral), New Delhi, between March 2016 and March 2019. Results: The disease showed a bimodal onset in both centres with 26 (26%) and 24 (24%) cases occurring in the age group of 31-40 years and 24 (24%) and 25 (25%) cases occurring in the age group of >60 years at CHAF (B) and AH (RR) respectively. B cell Lymphoma was the most common type of NHL seen in 85% and 89% patients, whereas Tcell lymphomas constituted 13% and 11% at CHAF (B) and AH (RR). 32(32%) patients presented with an Ann Arbor Stage 1 or 2 disease whereas 68(68%) patients were with Stage 3 or 4 disease at both the centers. IPI score was ≥3 in 45 % and 43% patients. Conclusions: NHL in India is a homogeneous and uniform disease. But there was increased detection of hepatosplenomegaly and associated hepatitis B/C in the southern part of India. Also, the occurrence of Cutaneous T cell lymphoma was only seen in the south India centre. The early stage NHLs has better survival and increase chance of complete response.
PD-L1 expression in malignant pleural effusion samples and its correlation with oncogene mutations in non-small cell lung cancer

Background Programmed death ligand 1 (PD-L1) tumor proportion score (TPS) is currently widely used for selection of immune therapies in non-small cell lung cancer (NSCLC). Most of samples for PD-L1 expression were obtained from tumor tissue. However, the feasible of malignant pleural effusion (MPE) cytological samples for PD-L1 detection is poorly reported. And the correlation between oncogene mutations and PD-L1 expression based on high-throughput sequencing is rarely studied. Methods NSCLC MPE cytological samples and partially paired tumor tissue from our institution analyzed for PD-L1 immunohistochemistry (IHC) using the clone SP263 pharmDx kit and evaluated genomic aberrations in all patients using next generation sequencing (NGS). Results One hundred and twenty-three MPE cell blocks and 29 paired tumor tissue were successfully tested for PD-L1 expression. PD-L1 TPS of ≥50% were seen in 18.7% (23/123) of all samples. The accordance of PD-L1 expression in tumor tissue and MPE samples was 86.2% (50% as cut-off value). PD-L1 TPS ≥50% tumors were significantly associated with EGFR wild-type (P=0.007), but, no correlation between other genes and PD-L1 expression. A trend of longer overall survival (OS) was observed in patients with PD-L1 TPS <50% than those TPS ≥50% (20.0 vs. 13.8 months, P=0.057). No difference of tumor mutational burden (TMB) was observed between patients with PD-L1 ≥50% and <50% (8.2/MB and 7.7/MB, P=0.47). Conclusions Our results suggest that cytological material is feasible for PD-L1 IHC analysis. Gene alterations could partially contribute to select the samples that with different PD-L1 expression. No correlation between the PD-L1 expression and TMB.
Stature estimation from digit length, bi-acromian and bi-illiac length: a study among two populations from eastern and north eastern India

Recognition of human remains is an indispensable element in medico-legal aspects and at the same time one of the major undertaking by the forensic anthropologist is the identification of fragmentary and mutilated remains. The identification of stature of the deceased, and comparisons with the ante-mortem data and age and sex assessment, has been subject matter of many forensic anthropology researches over the time and space.1,2 The process of identification is generally imperative in cases of mass disasters, explosions, and assault cases where the body is fragmented and establishing the identity of the victim being the challenge for investigator.3 It is here that accurate sexing of the human remains has the potential to primarily narrow down the search to a particular sex thereby giving sense of direction to the ongoing forensic investigation. Although genetic analysis of human population does not support concepts of innate racial differences with respect to innate abilities or characteristics, but human as polytypic and allopatric species demonstrate wide range of morphological, quantitative, polymorphic variations across the word. Being at the crossroads of migration, Indian populations have undergone complex and ancient admixture events over a long period4‒6 and have been the melting-pot of disparate ancestries originating from different parts of Eurasia and South-East Asia.6 Although the date of entry of modern humans into India remains uncertain but it is reasonable to consider by the middle Paleolithic period (50,000–20,000 years before present [ybp]), humans appear to have spread onto many parts of India.7 Contemporary ethnic India is a land of enormous genetic, cultural, and linguistic diversity.8,9 A more recent study exploring Indian genomic
Dairy cattle husbandry practices in Hulet Eju Enesie District, East Gojjam zone Ethiopia

Dairy farming is one of the livestock sub sectors that can provide income and employment for the economic sustainability of smallholder farmers (FAO, 2010). Hulet Eju Enesie district is one of the 18 districts in East Gojjam Zone of Amhara National Regional State which is conducive for livestock as well as dairy cattle production and other agricultural activities because of relatively enough feed resources if utilized properly and suitable environment. Because of this, milk production is widely practiced in the district (HEEDAFDO, 2016). However, there is no a previous research conducted to assess dairy cattle husbandry practices in the district. Therefore, this study was conducted to assess dairy cattle husbandry practices in Hulet Eju Enesie district East Gojjam Zone Ethiopia. A multi stage sampling procedures was used to select study PAs and Systematic random sampling was used to select 247 respondents for the interview. Data were collected using a pretested semi structured questionnaire and analyzed using descriptive statistics, chi square test, and analysis of variance by SPSS version 20 Software. The average herd size of cattle was 6.42±0.15 head per household and it is significantly varied (P<0.05) among the study areas with the highest herd size 7.73±0.25 head per HH in mid altitude, respectively. The major feed resources were crop residues and grazing land and the main sources of water were river and pipe water. The majority (79.8%) of respondents used natural mating using indigenous bull but 56% of respondents in Motta town used AI services. Anthrax and black leg were the most prevalent disease in the study area. In general, the feeding practice was not adequate for better productivity and the breeding system was mostly natural mating using local bull. In addition, low awareness of the dairy farmers also the main problem especially in proper calf management. Therefore, the husbandry practices should be improved by improving the awareness of the dairy farmers through provision of appropriate extension and training services.
A Fast Carrier Scheduling Algorithm for Battery-free Sensor Tags in Commodity Wireless Networks

New battery-free sensor tags that interoperate with unmodified standard IoT devices and protocols can extend a sensor network’s capabilities in a scalable and cost-effective manner. The tags achieve battery-free operation through backscatterrelated techniques, while the standard IoT devices avoid additional dedicated infrastructure by providing the unmodulated carrier that tags need to communicate. However, this approach requires coordination between devices transmitting, receiving and generating carrier, adds extra latency and energy consumption to already constrained devices, and increases interference and contention in the shared spectrum. We present a scheduling mechanism that optimizes the use of carrier generators, minimizing any disruptions to the regular nodes. We employ time slots to coordinate the unmodulated carrier while minimizing latency, energy consumption and overhead radio emissions. We propose an efficient scheduling algorithm that parallelizes communications with battery-free tags when possible and shares carriers among multiple tags concurrently. In our evaluation we demonstrate the feasibility and reliability of our approach in testbed experiments. We find that we can significantly reduce the excess latency and energy consumption caused by the addition of sensor tags when compared to sequential interrogation. We show that the gains tend to improve with the network size and that our solution is close to optimal on average.
Influence of Packaging Materials and Storage Duration on Quality of Flower Strings of Polianthes tuberosa Linn. cv. Prajwal

Flowers are one of the most important and unique gift of the nature to humanity. They are the adornments of the world with their valuable aesthetic, environmental, economic and medicinal properties. We know that flower have many uses in the life of human being. It is an integral part of lives in human society. The flower are mainly used for garland, veni, worship, table decoration, making bouquet, gajra, mandap decoration, bridal beds decoration as well as ceremonies and social functions. India has a long floriculture history and flowers are growing in an old enterprise. Reference to the flowers International Journal of Current Microbiology and Applied Sciences ISSN: 2319-7706 Volume 9 Number 3 (2020) Journal homepage: http://www.ijcmas. com
A linear relation to calculate one particle expectation value < r-1 > for 1 S 2 configuration for 2 < Z <

One particle expectation value <r-1> for 1S2 configuration for Z =2 to 10 are evaluated by using Hartree-Fock-Roothaan (HFR) wavefunction. A linear relation are determined to describe these results, and this relation have tested to check its ability to calculate one particle expectation value <r-1> for atoms with higher atomic numbers (Z = 2 to 100). Results are in good agreement with calculations given by [S.L. Saito Atomic Data and Nuclear Data Tables95, (2009) ,836-870] for Z<20.
Influence of two-month training program on anthropometry and VO2max in recreational athletes

: The aim was to evaluate the effect of a two-month training program on some anthropometric characteristics and maximum oxygen consumption (VO2 max) in male and female recreational athletes. Study included 62 participants, 30 males and 32 females. All participants were doing recreational sport, aged from 35 to 50 years old. In order to obtain accurate results, the following instruments were used: measuring tape, InnerScan body composition monitor Tanita BC-532 , and "Technogym" treadmill where they were performing submaximal aerobic test. Training process lasted for two months and consisted of two testing sessions. The training program has included three sessions per week for about 90 minutes. T-test for paired samples was used in the statistical program "SPSS", and results suggested that there was a positive effect of a two-month training process on certain anthropometric characteristics and the maximal oxygen uptake in both male and female subjects.
Prognostic value of the albumin-bilirubin grade in patients with hepatocellular carcinoma and other liver diseases

One of the most commonly used systems for grading liver function in hepatocellular carcinoma (HCC) patients is the Child-Pugh (CP) score. However, the CP scoring system is not without its shortcomings: for example, the cut-off values for the parameters are calculated arbitrarily and the assessment of ascites and hepatic encephalopathy is subjective. More recently, an alternative to traditional CP grade has emerged in the form of albumin-bilirubin (ALBI) grade. The predictive value provided for HCC patients by the ALBI grade is comparable to that of the CP grade; however, it can also surpass CP grade by greatly reducing subjectivity and further subdividing CP A patients into several different groups, thus improving the prognosis judgment and helping to inform clinicians’ optimal decision-making. The application of the ALBI grade into currently used HCC staging systems such as the Barcelona Clinic Liver Cancer (BCLC) staging system, the Cancer of the Liver Italian Program (CLIP) staging system, and the Japan Integrated Staging (JIS) score, etc., as well as newly produced systems like the ALBI-PLT grade, the ALBI and progression disease (ALBI-PD) grade and Modified Intermediate Stage of Liver Cancer (MICAN) criteria, greatly elevates prognostic power.
Removal of Indigo Carmine from Aqueous Solutions by Graphene Oxide: Kinetic and Equilibrium Studies

In this study the GO was oxidized and applied as an adsorbent for the removal of indigo carmine (IC) molecules from aqueous solution. The GO was prepared starting with natural graphite powder using the Hummers method. The GO was characterized by scanning electron microscopy (SEM) measurements. Also X-ray powder diffractometer was performed to determine the crystallinity of GO. The effects of various parameters such as solution pH (2.0-10.0), adsorbent dose (0.001 g to 0.1 g), contact time (5.0-145 min), and temperature (25-4oC) were investigated. The results demonstrated that the maximum percentage of IC adsorption was found at pH 5.0 and 40 min contact time with 0.02 g GO. Kinetic adsorption data were analysed using the first-order model and the pseudo-second-order model. The regression results indicated that the adsorption kinetics was more accurately showed by the pseudo-secondorder model. The equilibrium data in aqueous solutions were fitted to Langmuir and Freundlich isotherms and the equilibrium adsorption of IC was best described by the Langmuir model.
Early Cooperation Promotes the Private Provision of Public Goods∗

The assurance contract mechanism is often used to crowdfund public goods. This mechanism has weak implementation properties that can lead to miscoordination and failure to produce socially valuable projects. We extend the standard assurance contract with refund bonuses payable only if the campaign’s target is not reached, and experimentally examine fixed, proportional and early refund bonuses. Our special focus is on bonus designs aimed at encouraging early contributions and, thus, improving outcomes by promoting conditionally cooperative behavior. We find that refund bonuses can nearly double the rate of campaign success. Moreover, we find that even taking into account campaign failures, refund bonuses can be financially self-sustainable suggesting the real world value of extending assurance contracts with refund bonuses.