Miracle-dz/UniFAR-FTUs huggingface dataset:
Unicornuate Uterus with Rudimentary Horn: A Case Report

This is a case of a 22 year old nulligravid who presented with severe dysmenorrhea, and diagnosed with unicornuate uterus and an obstructed noncommunicating rudimentary horn, by pre-operative ultrasound. In this paper, the presentation, diagnosis and principles of surgical management of unicornuate uterus associated with a non-communicating rudimentary horn is presented. The embryological development of this anomaly and its association with renal agenesis are discussed. Background : Existing retrospective studies comparing the perinatal outcome in women with PCOS versus women without PCOS have proven that pre-pregnancy maternal overweight and obesity have a negative influence on the perinatal outcome of these women. Objective : To compare the pregnancy, delivery and neonatal outcomes in singleton pregnancies between overweight/obese and normal weight women with Polycystic Ovary Syndrome (PCOS). Materials and Methods : This is a retrospective cohort study of 185 women with PCOS who had achieved spontaneous pregnancy and delivered between January 2011 and December 2015. All data were retrieved from patient medical charts. Women diagnosed with polycystic ovary syndrome according to the Rotterdam criteria between the ages of 15 and 44 years who had conceived spontaneously were included. Results : Pregnancy loss occurred more frequently in the obese/overweight group as compared with the normal weight group (RR 1.3, 95% CI 1.0 - 1.8, p 0.04). Gestational hypertension and pre-eclampsia occurred less frequently in the group with normal BMI, although a statistical significance was not demonstrated (RR 1.1, 95% CI 0.6 - 2.3, p=0.37 and RR 1.0, 95% CI 1.5 - 1.9, p 0.49, respectively). The proportion of women who developed GDM was higher among women with increased BMI, however, this was also not statistically significant (RR 1.4, 95% CI 0.9 - 2.2, p=0.07). The prevalence of preterm birth was higher among overweight/obese women although this was also not statistically significant (RR 0.79, 95% CI 0.29 - 2.19, p 0.66). The proportion of women with a poor 1st minute APGAR score was significantly higher in the overweight and obese group as compared to the normal weight group (RR 1.78, 95% CI 1.10 - 2.89, p 0.012). Conclusion : Overweight and obese women with PCOS with an ongoing singleton pregnancy have an increased risk of pregnancy loss. Furthermore, they also have an increased risk of delivering babies with a poor APGAR score. Thus the importance of lifestyle modification in overweight and obese women with PCOS in order to reduce the risk of adverse perinatal outcomes should be emphasized.
Antidiabetic potential of ethanolic leaf extract of Crataeva magna in streptozotocin-induced diabetic model

Aim: In the present study, the ethanolic leaf extracts of Crataeva magna (ELECM) at various concentrations were prepared and anti-diabetic activity was evaluated. Materials and Methods: Diabetes was induced by single injection of streptozotocin (65 mg/kg, i.p. ) and various biochemical parameters were assessed using commercial available kits. Results: ELECM showed dose-dependent reversal of increase in blood glucose level in diabetic rats. Moreover, ELECM also reversed the abnormal lipid profile in diabetic rats as reflected by decrease level of total cholesterol, triglyceride, very low-density lipoprotein (VLDL), and LDL and increase level of high-density lipoprotein. Moreover, ELECM also showed in vivo antioxidant activity by increasing level of antioxidant enzymes such as reduced glutathione (GSH), sodium dismutase, and catalase along with decreasing oxidant markers such as thiobarbituric acid level. Conclusion: In the light of the above consideration, the results of the study revealed that ELECM showed promising antidiabetic activity in a dose-dependent manner.
Tkachenko modes and their damping in the vortex lattice regime of rapidly rotating bosons

We have found an exact analytical solution of the Bogoliubov-de Gennes equations for the Tkachenko modes of the vortex lattice in the lowest Landau level (LLL) in the thermodynamic limit (geometry of an infinite plane) at any momenta and calculated their damping rates. At finite temperatures both Beliaev and Landau damping leads to momentum-independent damping rates in the low-energy limit, which shows that, at sufficiently low energies, Tkachenko modes become strongly damped. We then found that the mean-square fluctuations of the density grow logarithmically at large distances, which indicates that the state is ordered in the vortex lattice only on a finite (although exponentially large) distance scale and introduces a low-momentum cutoff. Using this circumstance we showed that at finite temperatures the one-body density matrix undergoes an exponential decay at large distances.
Inclined Magnetic Field on Second Grade Nanofluid Flow from an Inclined Stretching Sheet with Nonlinear Mixed Convection

Present investigation aims to probe into the problem of nonlinear mixed convection flow of second grade nanofluid flow due to an inclined stretching sheet. The simultaneous impacts of inclined magnetic field of acute angle and convective boundary conditions are taken into deliberation. The system of highly nonlinear partial differential equations is transformed into non-linear ordinary differential equations with the aid of similarity transformation variables. The solutions are generated numerically via the Runge-Kutta-Fehlberg Method (RKF 45) and then presented in the form of graph. Obtained results are first authenticated by way of comparison with the documented results of previous publications. Finding reveals that the inclined angle together with magnetic parameter have decelerated the fluid flow. Besides, escalating both Brownian motion and thermophoresis diffusion parameters have enhanced the temperature. In contrast, the concentration profile has reduced owing to incremented Lewis number.
Specification Tests for Asymmetric GARCH

In this paper I present two new Lagrange multiplier test statistics designed for testing the null of GARCH (1,1), against the alternative of asymmetric GARCH. For one test the alternative is the generalized QARCH (1,1) model of Sentana [1995], and for the other the alternative is the logistic smooth transition GARCH (1,1) model of Hagerud [1996], and Gonzalez-Rivera [1996]. In the study I present small sample properties for the two statistics. The empirical size is shown to be equal to the theoretical for reasonable sample sizes. Furthermore, I show that the power of both tests is superior to that of the asymmetry tests proposed by Engle and Ng [1993]. This is true even if the true data generating process is not the GQARCH or LSTGARCH model, but any of the models, EGARCH, GJR, TGARCH, A-PARCH, and VS-ARCH. Thus, the two tests are in fact tests for general GARCH asymmetry,.
MULTI-MACHINE DETERMINATION OF SOL-TO-CORE MULTI-Z IMPURITY TRANSPORT IN ADVANCED CONFINEMENT REGIMES

Low to high-Z impurity transport spanning from the scrape-off-layer (SOL) to the plasma core has been studied on multiple US fusion devices in a wide range of confinement regimes. As part of the 2020 US Joint Research Target (JRT), 8 datasets obtained from Alcator C-Mod, DIII-D, and NSTX/NSTX-U were used to perform coordinated research to understand generation of impurities from material surfaces and their transport to the plasma core. In the SOL and divertor region, state-of-the-art SOL modelling of tungsten was validated against collector probe measurements, providing evidence for strong convective transport and for near-SOL impurity accumulation. Analytic modelling and spectroscopic measurements of tungsten erosion and re-deposition in the SOL indicated the importance of electric-field effects and gyro-motion in regulating prompt re-deposition. The first 3D modelling of boron SOL transport in DIII-D linked changes in parallel friction forces in the SOL to spatial boron distributions and qualitatively reproduced boron density asymmetries measured in the DIII-D divertor. Novel main ion charge exchange measurements combined with modelling displayed the role of impurity ionization and inward neoclassical convection of impurities in the recovery of the pedestal following ELMs. In the plasma core, cross-machine datasets were used to validate leading neoclassical and turbulent transport models and establish actuators for the regulation of core impurity transport in a wide range of plasma conditions. Flexible beam configurations on DIII-D were leveraged to definitively demonstrate the negligible role of roto-diffusion in impurity peaking in H-mode conditions. Comparison of cross-machine databases confirmed the robust correlation of impurity and electron density peaking and were used to validate both turbulent and neoclassical models, revealing areas of parameter space demonstrating strong agreement and disagreement with modelling. In a wide range of advanced operating regimes, neoclassical peaking of low & high-Z impurities was observed, and could be eliminated via modest central electron-heating, independent of regime and impurity studied. This paper presents a description of the experiments and analysis performed that help shed light on impurity dynamics in high confinement regimes.
Claim Extraction and Law Matching for COVID-19-related Legislation

To cope with the COVID-19 pandemic, many jurisdictions have introduced new or altered existing legislation. Even though these new rules are often communicated to the public in news articles, it remains challenging for laypersons to learn about what is currently allowed or forbidden since news articles typically do not reference underlying laws. We investigate an automated approach to extract legal claims from news articles and to match the claims with their corresponding applicable laws. We examine the feasibility of the two tasks concerning claims about COVID-19-related laws from Berlin, Germany. For both tasks, we create and make publicly available the data sets and report the results of initial experiments. We obtain promising results with Transformer-based models that achieve 46.7 F1 for claim extraction and 91.4 F1 for law matching, albeit with some conceptual limitations. Furthermore, we discuss challenges of current machine learning approaches for legal language processing and their ability for complex legal reasoning tasks.
ACCORD: A Scalable Multileader Consensus Protocol for Healthcare Blockchain

Blockchain is an emerging distributed and decentralized technology that promises to revolutionize the healthcare sector by securely storing and maintaining incorruptible electronic health record data. Consensus protocols are at the core of blockchain technology. They establish security and integrity in the system by ensuring that the majority of miners are in agreement on all transactions and blocks added to the distributed ledger. While many consensus protocols have been proposed, most of them require heavy computation and are not scalable. In this work, we propose a novel permissioned consensus protocol, named ACCORD, a multi-leader (quorum-based) protocol that achieves fork-resistance, robustness, and scalability. To achieve this, ACCORD consists of three distinct components: 1) an asynchronous quorum selection procedure to designate the creators of future blocks; 2) a block creation protocol run by the quorum to prevent omissions in the presence of honest quorum members; and 3) a decentralized arbitration protocol to ensure consensus by voting. Additionally, we implemented the protocol and conducted experiments to demonstrate scalability, robustness, and fairness.
Impact of Income Expectations, Family Environment on Entrepreneurial Interests with Self-Efficacy as an Intervening Variable

The interest in entrepreneurship in UNESA Labschool High School students is very low, and employment is reduced due to the COVID-19 pandemic that is detrimental to most business people. This condition increases the number of unemployed people in Indonesia, one way to overcome this is to foster an interest in entrepreneurship since it was still in school in accordance with Presidential Instruction No. 9 of 2016. This study aims to determine the influence of income expectations, family environment, and self-efficacy on students' entrepreneurial interests. This study used quantitative methods and data collection using questionnaires with a total of 112 respondents. The data was processed with the WarpPLS application and with SEM analysis can determine the influence of self-efficacy variables able to mediate income expectation variables and family environment variables with significant results on entrepreneurial interest variables. The result of this study is that income expectations have a positive and insignificant effect on entrepreneurial interest, but indirectly (through intervening variables) have a positive and significant effect on entrepreneurial interest. The family environment directly has a significant and positive effect on the interest in entrepreneurship, the family environment indirectly has a positive and significant effect on the interest in entrepreneurship
EFFECTS OF BIOCHAR PRODUCED FROM TROPICAL RICE HUSK AND PEANUT SHELL AT DIFFERENT PROCESSING TEMPERATURES ON IN VITRO RUMEN FERMENTATION AND METHANE PRODUCTION

The aim of this study was to investigate the effects of biochar produced from tropical biomass resources at different processing temperatures on methane production and rumen fermentation in vitro . Two available tropical biomass resources of rice husk and peanut shell were used for pyrolysis at three temperature levels of 300, 500 and 700 o C. Biochar was supplemented at 3% in diets of dry matter basis. In vitro fermentation characteristics and methane production were measured at 4, 24 and 48h after incubation. Results showed that there were no significant differences in terms of (i) gas and methane production, (ii) dry matter and organic matter digestibility (iii) pH and NH 3 -N concentration between diets supplemented either rice husk or peanut shell drived biochar in an in vitro system (P>0.05). Whereas, different processing temperatures affected on total gas, production of methane and NH 3 -N concentration (P≤0.05), increasing processing temperature decreased methane production. There were no interactions between biomass resources and processing temperature on in vitro rumen fermentation and methane production. These results implicate that rice husk and peanut shell derived biochar produced at 700 o C can be used to mitigate methane emission from cattle production, further in vivo studies are required to confirm practical parameters. In vitro fermentation, Methane
Scoring Situational Judgment Tests Using Profile Similarity Metrics

Abstract : This paper describes the application of profile similarity metrics to score Situational Judgment Tests (SJTs) that utilize rating scales to register examinee responses. The paper presents and discusses mathematical analyses that decompose distance-based measures into component indices based on correlation, dispersion and elevation metrics. The mathematical analyses demonstrate that distance measures represent a mixture of variance that can be associated with these separate components. Comparing the validities of distance and component indices using Leader Knowledge Test (LKT) data supports conclusions that the use of component indices (i.e., correlation, dispersion and elevation scores) improves the validity of SJTs that utilize rating scales.
SPIRAL PATTERNS IN PLANETESIMAL CIRCUMBINARY DISKS

Planet formation scenarios and the observed planetary dynamics in binaries pose a number of theoretical challenges, especially concerning circumbinary planetary systems. We explore the dynamical stirring of a planetesimal circumbinary disk in the epoch when the gas component disappears. For this purpose, following theoretical approaches by Heppenheimer and Moriwaki & Nakagawa, we develop a secular theory of the dynamics of planetesimals in circumbinary disks. If a binary is eccentric and its components have unequal masses, a spiral density wave is generated, engulfing the disk on a secular timescale, which may exceed 107 yr, depending on the problem parameters. The spiral pattern is transient; thus, its observed presence may betray a system’s young age. We explore the pattern both analytically and in numerical experiments. The derived analytical spiral is a modified lituus; it matches the numerical density wave in the gas-free case perfectly. Using the smoothed particle hydrodynamics scheme, we explore the effect of residual gas on the wave propagation.
Strategic Alignment as an Antecedent of Customer Satisfaction: A Review of Literature

: The economic globalization forces organizations to evolve in an ever more competitive, complex, and continuously changing and transforming environment. Business enterprises have to anticipate the market evolution triggered by changes in the environmental conditions, adopt strategic options for optimal fit, make a competitive value proposition, and to implement strategies able to establish and systematically address fundamental customers’ concerns in pursuit of the strategic objectives. A vast body of empirical literature indicates that service quality and customer satisfaction have leads to profitability and better performance of firms in the market place. The growth and diversity in the international business has brought about new challenges and heightened the competition of firms across the globe and as such firms have been forced to re-examine themselves internally in order to improve their performance. Organization should leverage on strategic alignment to create customer experience that would results in repeat purchase, customer retention, brand loyalty and customer referrals. Strategic alignment enables organization is central to matching the organizations decisions with actions, operations, processes, resources and capabilities which support achievement of strategic goals. This study sought to review existing conceptual, theoretical and empirical literature on strategic alignment and customer satisfaction with a view to highlighting the knowledge gaps suitable to form basis for future research work. Existing empirical literature on strategic alignment is replete with evidence of results that are not conclusive, different conceptualization of strategic alignment as well as diversity of contextual variables. The review also revealed key indicators of customer satisfaction as one of the outcomes of strategic alignment in organizations. Ultimately, a set of relationships were for the dimension strategic alignment and customer satisfaction were modeled as a guide for future research work in the field of strategic management.
A New Control Strategy for High-Pressure Homogenization to Improve the Safety of Injectable Lipid Emulsions

Intravenous lipid emulsions are biocompatible formulations used as clinical nutrition products and lipid-based delivery systems for sparingly soluble drugs. However, the particle-size distribution is associated with risks of embolism. Accordingly, the mean particle diameter (MPD) and particle-distribution tailing (characterized as the pFAT5 value) are critical quality attributes that ensure patient safety. Compliance with the limits stated in the United States Pharmacopoeia is ensured by high-pressure homogenization, the final step of the manufacturing process. The US Food and Drug Administration’s Quality-by-Design approach requires a control strategy based on deep process understanding to ensure that products have a consistent and predefined quality. Here we investigated the process parameters of a jet-valve high-pressure homogenizer, specifically their effect on the MPD, pFAT5 value and droplet count (determined by microscopy) during the production of a Lipofundin MCT/LCT 20% formulation. We provide deep insight into droplet breakup and coalescence behavior when varying the process pressure, emulsion temperature and number of homogenization cycles. We found that high shear forces are not required to reduce the pFAT5 value of the particle distribution. Finally, we derived a control strategy for a rapid and cost-efficient two-cycle process that ensures patient safety over a large control space.
phosphorylation-independent modes of modulation of shaker family voltage-gated potassium channels by SRC family protein

Venom-derived ion channel inhibitors have strong channel selectivity, potency, and stability; however, tracking delivery to their target can be challenging. Herein, we utilized luminescent quantum dots (QDs) conjugated to margatoxin (MgTx) as a traceable vehicle to target a voltage-dependent potassium channel, Kv1.3, which has a select distribution and well-characterized role in immunity, glucose metabolism, and sensory ability. We screened both unconjugated (MgTx) and conjugated MgTx (QD-MgTx) for their ability to inhibit Shaker channels Kv1.1 to Kv1.7 using patch-clamp electrophysiology in HEK293 cells. Our data indicate that MgTx inhibits 79% of the outward current in Kv1.3-transfected cells and that the QD-MgTx conjugate is able to achieve a similar level of block, albeit a slightly reduced ef ﬁ cacy (66%) and at a slower time course (50% block by 10.9 (cid:1) 1.1 min, MgTx; vs. 15.3 (cid:1) 1.2 min, QD-MgTx). Like the unbound peptide, the QD-MgTx conjugate inhibits both Kv1.3 and Kv1.2 at a 1 nM concentration, whereas it does not inhibit other screened Shaker channels. We tested the ability of QD-MgTx to inhibit native Kv1.3 expressed in the mouse olfactory bulb (OB). In brain slices of the OB, the conjugate acted similarly to MgTx to inhibit Kv1.3, causing an increased action potential ﬁ ring frequency attributed to decreased intraburst duration rather than interspike interval. Our data demonstrate a retention of known biophysical properties associated with block of the vestibule of Kv1.3 by QD-MgTx conjugate compared to that of MgTx, inferring QDs could provide a useful tool to deliver ion channel inhibitors to targeted tissues in vivo