Miracle-dz/UniFAR-FTUs huggingface dataset:
Mining Patient Flow Patterns in a Surgical Ward

: Surgery is a highly critical and costly procedure, and there is an imperative need to improve the efﬁciency in surgical wards. Analyzing surgical patient ﬂow and predicting cycle times of different peri-operative phases can help improve the scheduling and management of surgeries. In this paper, we propose a novel approach to mining temporal patterns of surgical patient ﬂow with the use of Bayesian belief networks. We present and compare three classes of probabilistic models and we evaluate them with respect to predicting cycle times of individual phases of patient ﬂow. The results of this study support previous work that surgical times are log-normally distributed. We also show that the inclusion of a clustering pre-processing step improves the performance of our models considerably.
Randomized Control Trial of Video-Feedback Intervention to Promote Positive Parenting in Lima, Peru: A Pilot Study

This randomized pilot study explored the viability and effectiveness of the Video-feedback Intervention to Promote Positive Parenting and Sensitive Discipline (VIPP-SD) for improving sensitivity in a group of 14 mothers of lower and upper socioeconomic status in Lima, Peru. Maternal sensitivity was assessed using the Maternal Behaviour Q-Set 3.1, based on the observation of one hour of free interactions at home. The effectiveness of the intervention was calculated on the basis of the difference between preand post-intervention sensitivity scores. Overall, we found no significant differences between the intervention group and the control group; however, when participants were sorted based on their pre-intervention sensitivity levels, low-sensitivity mothers who participated in the VIPP-SD program showed a significant improve in global sensitivity and in the Sensitive vs. Insensitive and Disengaged profiles, compared to low-sensitivity mothers in the control group. These findings are an initial contribution to establishing the viability and effectiveness of the VIPP-SD for the improvement of maternal sensitivity, especially for groups of low-sensitivity mothers in situations of greater psychosocial vulnerability.
Effect of laparoscopic insemination on reproductive performance of indigenous Cine Capari sheep

The feasibility of use of laparoscopic artificial insemination (LAI) method was investigated in endangered indigenous Cine Capari sheep breed under conservation. Setting the mating plans and controlling the inbreeding may be possible with the use of effective artificial insemination techniques. In the present study, 23 and 46 ewes showing estrus at 2002–2003 and 2008–2009 mating seasons were laparoscopically inseminated with diluted fresh semen from 6 and 9 rams, respectively. Data were evaluated with respect to gestation length, litter size, duration between sponge removal and beginning of estrus activity (DBSR-BOA), duration between beginning of estrus activity and LAI (DBSR-LAI) and AI success rate. The least square means for mentioned traits were found as 150.3 days, 1.36, 39.98 h, 22.31 h and 69.57% for 2003–2004 lambing season and 148.70 days, 1.41, 41.18 h, 18.35 h and 63.04% for 2008–2009 lambing season, respectively. The difference between means of years were not statistically significant for all the evaluated variables except gestation length. Our results showed that LAI will be a useful tool in activities to conserve Cine Capari sheep as a genetic resource.
Survey of physicians' views on the clinical implementation of pharmacogenomics-based personalized therapy

Despite quantitative increases and qualitative advances in pharmacogenomics (PGx) research, the clinical implementation of PGx-based personalized therapy has still been limited. The objective of this study was to assess physicians' self-reported knowledge of PGx-based personalized therapy, and to explore the most problematic and highest priority barriers preventing physicians from applying PGx into clinical practice under the Korean healthcare system. A 36-question survey was distributed to 53 physicians with various specialties in Korea. In the physicians' self-perceived knowledge, twenty-eight physicians (53%) reported a lack sufficient knowledge about PGx. The perceived largest barrier to clinical implementation of PGx was the high cost of PGx testing, followed by a lack of PGx education for healthcare providers or lack of clinical PGx experts. Physicians without clinical PGx experience or with indirect experience reported that the largest barrier to clinical implementation of PGx was the high cost of PGx testing, while physicians with clinical PGx experience pointed out that a lack of patients' education was the major concern, followed by a lack of PGx education for healthcare providers or lack of clinical PGx experts. The highest priority problem was reported to be a lack of actionable guidelines for drug selection and dosing using PGx. In conclusion, we should increase and expand extensive educational programs for healthcare providers and patients, and to develop and establish a clinical decision support systems for PGx-based personalized therapy in Korea.
The Relationship between Sleep Quality and Blood Pressure in Patients with Hypertension

Background: Hypertension is one of the non-communicable diseases (NCDs) that is commonly found in Indonesia and the majority of people suffering from hypertension are females with the percentage of 28,80% with late detection of hypertension leads to serious health problems such as organ failure. Lousy sleeping habit or lack of sleeping hours may increase the risk of hypertension, heart disease, and other cardiovascular diseases. Purpose: This study aimed to investigate the relationship between sleep quality with patients’ blood pressure in public health center (puskesmas) in Mojolangu region of Malang city. Methods: The study was analytic observational with cross-sectional study design. The population of this study was all hypertension patients registered in puskesmas Mojolangu. Respondents were selected based on the period of hypertension, so that were 30 respondents included through inclusion and exclusion criteria. The dependent variable was blood pressure, while the independent variable was sleep quality. Data were analyzed through the contingency coefficient. Results: Most of the patients with abnormal blood pressure were females with the percentage of 53,30%, aged 41-60 years old (43,30%) with lousy sleep quality (66,70%). There was a strong correlation between blood pressure in patients with hypertension and sleep quality by 0,65. Conclusion: Most of the respondents with lousy sleep quality will have high blood pressure. Therefore, assistance will be needed on hypertension patients.
Transcranial magnetic stimulation of the brain: guidelines for pain treatment research

Abstract Recognizing that electrically stimulating the motor cortex could relieve chronic pain sparked development of noninvasive technologies. In transcranial magnetic stimulation (TMS), electromagnetic coils held against the scalp influence underlying cortical firing. Multiday repetitive transcranial magnetic stimulation (rTMS) can induce long-lasting, potentially therapeutic brain plasticity. Nearby ferromagnetic or electronic implants are contraindications. Adverse effects are minimal, primarily headaches. Single provoked seizures are very rare. Transcranial magnetic stimulation devices are marketed for depression and migraine in the United States and for various indications elsewhere. Although multiple studies report that high-frequency rTMS of the motor cortex reduces neuropathic pain, their quality has been insufficient to support Food and Drug Administration application. Harvard's Radcliffe Institute therefore sponsored a workshop to solicit advice from experts in TMS, pain research, and clinical trials. They recommended that researchers standardize and document all TMS parameters and improve strategies for sham and double blinding. Subjects should have common well-characterized pain conditions amenable to motor cortex rTMS and studies should be adequately powered. They recommended standardized assessment tools (eg, NIH's PROMIS) plus validated condition-specific instruments and consensus-recommended metrics (eg, IMMPACT). Outcomes should include pain intensity and qualities, patient and clinician impression of change, and proportions achieving 30% and 50% pain relief. Secondary outcomes could include function, mood, sleep, and/or quality of life. Minimum required elements include sample sources, sizes, and demographics, recruitment methods, inclusion and exclusion criteria, baseline and posttreatment means and SD, adverse effects, safety concerns, discontinuations, and medication-usage records. Outcomes should be monitored for at least 3 months after initiation with prespecified statistical analyses. Multigroup collaborations or registry studies may be needed for pivotal trials.
Intern and congregant perceptions of the impact of a United Methodist ministry internship program in rural Missouri

vi This qualitative study examines a ministry internship program at a rural regional university in Missouri. The study sought to determine the impact of the internship on both interns in the program and on congregants in churches served by the program. Guided by the lens of self-efficacy as identified originally by Bandura (1977), the researcher conducted interviews, focus groups, and examined archival data to ascertain impact. Completed research helped identify eight areas of impact. The internship allowed for support and transformation of both interns and congregants throughout its duration. Interns were able to gain a realistic understanding of the ministry field. Interns were able to reflect on their practice through differential outcomes. Interns were able to ascertain a potential calling to vocational ministry. Congregants reported an influx of new ideas into their churches. Rural churches were able to stay open. Many interns went on to become young vocational ministers within the United Methodist Church. Both congregants and interns reported the internship allowed them to come closer to God.
Evaluating the reliability of a tool to measure the quality of gastrointestinal multidisciplinary cancer conferences: A generalizability study

Background Lamb et al. developed the metric for the observation of decision-making tool (MTB-MODe) to evaluate the quality of urologic multidisciplinary cancer conferences (MCCs) in the United Kingdom. We used generalizability theory to assess the reliability of a modified version of MTB-MODe in a North American context. Specifically, we wished to determine if the tool could distinguish between high- and low-quality MCC decision-making. Methods Two assessors independently evaluated two MCCs (MCC1, MCC2) using the modified MTB-MODe. Generalizability theory was used to assess overall tool reliability and to identify sources most likely to contribute to variance in reliability scores. A total of 60 cases were evaluated. Results The overall reliability scores of MCC1 and MCC2 were 0.72 and 0.74, respectively. Inter-rater reliability scores were reasonable (>0.55) and raters did not contribute significantly to variance in reliability scores. Internal consistency of the individual MTB-MODe items was low, demonstrating that items were not highly correlated. Conclusions The MTB-MODe reliably assessed the quality of individual MCC cases. Raters did not contribute significantly to reliability scores, suggesting that the tool can be successfully implemented using a single rater. Low internal consistency of the MTB-MODe items demonstrates that the tool can be used to provide feedback on individual tool items. Such data can be used by stakeholders to help improve MCC quality.
Study of serum ferritin and HbA1c in type 2 diabetes mellitus

Introduction: Diabetes is a metabolic disorder characterized by hyperglycaemia which is associated with rise in the HbA1c. Excess iron damages ? -cells of pancreas due to oxidative stress which can contribute to pathogenesis of diabetes mellitus. Recent research reveals that HbA1c concentration also increases in iron deficiency anemia as well. This fact is hence important as in diabetic patient, the HbA1c may not be only correlated with blood sugar level but also iron status, if the patient happens to be suffering from iron deficiency anemia. Objectives: Correlation of HbA1c and glucose level with serum ferritin. Materials and Methods: A Cross sectional pilot study was conducted in 80 diabetic patients at Central Clinical Laboratory, MIMER Medical College, Talegaon. Result: There was a positive correlation between serum ferritin and Fasting sugar, postprandial sugar, HbA1c. Serum ferritin is significantly related to Fasting Sugar (P value- 0.0028); postprandial sugar (P value- 0.0118) and glycated Haemoglobin (P value-0.0007). P value Conclusion: Serum ferritin is el­evated in patients with type 2 diabetes mellitus and can be used as a marker for glycemic control in diabetic patients. Keywords: Serum ferritin, Glycated haemoglobin, Type 2 diabetes mellitus.
Comparação entre BDNA e PCR na detecção da carga viral do HIV-1

Introduction: AIDS (Acquired Immunodeficiency Syndrome) is characterised by a severe immune dysfunction caused by the HIV (Human Immunodeficiency Virus). The HIV viral load quantification is an essential tool to monitor HIV-infected patients. The HIV quantification is a disease progression marker and it is a key indicator in treatment efficacy. Inaccurate viral RNA values may subsequently lead to inappropriate treatment decisions hence accurate quantification methods are necessary. Several different methodologies are available to quantify the HIV viral load: a number of them are based on nucleic acid detection and others in detection of enzymes and antigens. Automation is also variable among these methods in addition to differences in isolation, amplification and detection. Several studies have been carried out to evaluate their correlation and agreement and some have evidenced discordant viral load values assessed by different assays. The knowledge about these differences should be taken in to account when analysing viral load results, particularly when low-level viraemia is concerned or those close to endpoints employed for definition of virological failure. Objectives: In this study, two methods to quantify viral load are evaluated: one is based on real-time PCR (AmpliPrep TaqMan HIV-1 v2.0) and the other is based on branched-DNA technology (Siemens Versant HIV-1 RNA 3.0). Methods: 1000 plasma samples received at the HIV/GUM Research Laboratory within Chelsea and Westminster Hospital for HIV-1 viral load quantification between December 2009 and January 2010 were tested by both Cobas AmpliPrep TaqMan HIV-1 v2.0 and Siemens Versant HIV-1 RNA 3.0 methods. Results: Results obtained show that Cobas AmpliPrep TaqMan HIV-1 v2.0 PCR systematically overquantifies the viral loads results when compared to bDNA Siemens Versant HIV-1 RNA 3.0. Conclusion: The overquantification by Cobas AmpliPrep TaqMan HIV-1 v2.0 over bDNA Siemens Versant HIV-1 RNA 3.0 is likely to be a result of its increased sensitivity. We
Mobilising vitamin D from adipose tissue: The potential impact of exercise

Abstract Vitamin D is lipophilic and accumulates substantially in adipose tissue. Even without supplementation, the amount of vitamin D in the adipose of a typical adult is equivalent to several months of the daily reference nutrient intake (RNI). Paradoxically, despite the large amounts of vitamin D located in adipose tissue, individuals with obesity are often vitamin D deficient according to consensus measures of vitamin D status (serum 25‐hydroxyvitamin D concentrations). Thus, it appears that vitamin D can become ‘trapped’ in adipose tissue, potentially due to insufficient lipolytic stimulation and/or due to tissue dysfunction/adaptation resulting from adipose expansion. Emerging evidence suggests that exercise may mobilise vitamin D from adipose (even in the absence of weight loss). If exercise helps to mobilise vitamin D from adipose tissue, then this could have important ramifications for practitioners and policymakers regarding the management of low circulating levels of vitamin D, as well as chronically low levels of physical activity, obesity and associated health conditions. This perspective led us to design a study to examine the impact of exercise on vitamin D status, vitamin D turnover and adipose tissue vitamin D content (the VitaDEx project). The VitaDEx project will determine whether increasing physical activity (via exercise) represents a potentially useful strategy to mobilise vitamin D from adipose tissue.
Challenges in trauma resuscitation: A systematic review

Introduction: Trauma resuscitations are complicated, high-risk, and time-sensitive actions that need the coordination of different specialists arriving from multiple areas in the hospital. This systematic review aimed to understand the main key challenges of trauma resuscitations using a broad search in various database. Methods: A systematic review of published articles between the year 2000 and 2016 were conducted using different electronic databases such as Google Scholar, Medline, Embase, and Scopus to identify studies evaluating trauma resuscitations challenges. Different keywords were used in this study to recognize relevant articles. The titles of all articles were scanned in the first stage. Irrelevant articles were omitted and the abstracts of the rest articles were reviewed in the second stage. Finally, the full text of all articles which met the inclusion and exclusion criteria were reviewed and a data extraction sheet was made to summarize all the articles. Data were analyzed descriptively. Results: Twenty five studies were reviewed including; RCT (3 studies), QRCT (5 studies), and descriptive study (17 studies). The results showed that there are four main trauma resuscitation challenges including pre-hospital challenges, error-related challenges, equipment and technical challenges, and finally general challenges. Conclusions: Trauma resuscitation is one of the most critical aspects of emergency care. It is necessary to promote resuscitation care and focus on patient outcomes in terms of mortality and more importantly, functional outcomes. Considering these main factors affecting trauma resuscitation will improve patients' outcomes and help those who are engaged in providing services.
Comparative evaluation of interventional radiology modalities in treatment of liver abscess

Background: Liver abscess (LA) is a superlative cavity in the liver resulting from the invasion and multiplication of microorganism. With progress of interventional radiology, alternative to surgery in form of percutaneous drainage (PD) have become popular. PD can be accomplished by either percutaneous catheter drainage (PCD) or percutaneous needle aspiration (PCNA). This study was conducted to assess the PD as a definitive treatment modality for LA and comparison of PCD and PCNA.Methods: The study was conducted in the Radiodiagnosis Department. All patients of LA were evaluated for age, sex, duration of complaints, type of intervention performed, and outcome etc. After diagnosis, patients were managed by PCD or PCNA. Response to treatment, duration of stay, and overall success of both the modalities were evaluated.Results: The duration of this study was 34 months. During this period, 57 patients were evaluated. Of total, 29 underwent PCD and 28 PCNA. Male to female ratio was 2:1. Right lobe was involved in 48. Mean volume of abscess cavity was 356.44 ml. All patients who underwent PCD responded to the treatment; however, 8 patients who were treated by PCNA did not respond completely. Outcome was statistically related to type of treatment modality. PCD was statistically superior to PCNA (P <0.05). Conclusions: PD may be regarded as first line of treatment for LA. It appears that PCD is better as compared to PCNA for successful outcome of patients.
Lameness cases in cattle reported to the University Veterinary Hospital, Universiti Putra Malaysia from 2013 to 2017

This study was designed to characterise the lameness cases in cattle reported to the University Veterinary Hospital (UVH) of Universiti Putra Malaysia (UPM), Serdang, Selangor. Medical records from 2013 to 2017 were reviewed and 136 cases of cattle diagnosed as lameness were retrieved. Information concerning signalment, location of lesions, and cause of lameness was analysed. Majority of the cases were reported in dairy (77%) compared with beef cattle (23%) with 73% being under semi-intensive management system. Foot lesions accounted for about 51% of cases, while lesions were more on the hindlimbs than the forelimbs (p 0.05) between foot lesions categorised either as infectious or non-infectious causes. A higher proportion (p<0.05) of the cases were weight-bearing rather than non-weight bearing lameness, thus suggesting mild to moderate lameness. The findings suggest that routine claw trimming may be necessary to improve weight-bearing balance as majority of the foot lesions were present on the hindlimbs. The findings depict that lameness remains a major health issue in dairy herds and information herein may assist practitioners in addressing such painful condition.
Incidence of postoperative hyponatremia in neurosurgical patients in a hospital in Southern Colombia

Introduction: Hyponatremia is the most frequently encountered electrolyte disorder in hospitalized patients, and its incidence is even greater when a neurological condition is present. A significant association has been found between hyponatremia and increases in mortality rates. Objective: To describe the incidence of hyponatremia in neurosurgical patients of a university hospital in southern Colombia. Methods: Descriptive, observational study that analyzed the medical records of adult patients admitted to the intensive care unit after having undergone a neurosurgical procedure in the period between 2014 and 2015. Perioperative characteristics and neurological outcomes were compared, central trend and scatter were calculated, and statistical confidence tests were applied. Results: A total of 79 patients were included in the study. The median age was 40 years and 73.4% were male. The most frequent diagnosis was head injury, followed by space-occupying lesion and non-traumatic subarachnoid hemorrhage. The incidence of hyponatremia was 25.3%; patients with a diagnosis of subarachnoid hemorrhage were 8 times more likely to have hyponatremia (odds ratio 8.0, 95% confidence interval: 1.777–36.018). Mortality for the group of patients presenting hyponatremia was 35%, and unfavorable neurological outcomes were present in 80%. Conclusions: Neurosurgical patients with a diagnosis of subarachnoid hemorrhage or space-occupying lesion associated with hyponatremia have a less favorable neurologic outcome, without circumstantially affecting mortality.