Miracle-dz/UniFAR-FTUs huggingface dataset:
3D mapping for the identification of the fossa ovalis in left atrial ablation procedures: a pilot study of a first step towards an electroanatomic-guided transseptal puncture.

AIMS Transseptal puncture (TP) for left atrial (LA) catheter ablation procedures is routinely performed under fluoroscopic guidance. To decrease radiation exposure and increase safety alternative techniques are desirable. The aim of this study was to assess whether right atrial (RA) electroanatomic 3D mapping can reliably identify the fossa ovalis (FO) in preparation of TP. METHODS AND RESULTS Between May 2019 and August 2019, electroanatomic RA mapping was performed before TP in 61 patients with paroxysmal or persistent atrial fibrillation. Three electroanatomic methods for FO identification, mapping catheter-induced FO protrusion, electroanatomic-guided analysis, and voltage mapping, were evaluated and compared with transoesophageal echocardiography (TOE). Mapping catheter-induced FO protrusion was feasible in 60 patients (98%) with a mean displacement of 6.8 ± 2.5 mm, confirmed by TOE, and proofed to be the most valuable and easiest marker for FO identification. Electroanatomic-guided analysis localized the FO midpoint consistently in the lower half (43 ± 7%) and posterior (18.2 ± 4.4 mm) to a line between coronary sinus and vena cava superior. Analysis of RA voltage maps during sinus rhythm (n = 40, low-voltage cut-off value 1.0 and 1.5 mV) allowed secure FO recognition in 33% and 18%, only. A step-by-step approach, combining FO protrusion (first step) with anatomy criteria in case of protrusion failure (second step) would have allowed for the correct localization of a TP site within the FO in all patients. CONCLUSION Right atrial electroanatomic 3D mapping prior to TP proofed to be a simple tool for FO identification and may potentially be of use in the safe and radiation-free performance of TP prior to LA ablation procedures.
Mechanical Adaptations of Skinned Cardiac Muscle in Response to Dietary-Induced Obesity During Adolescence in Rats.

Childhood obesity is a major risk factor for heart disease during adulthood, independent of adulthood behaviours. Therefore, it seems that childhood obesity leads to partly irreversible decrements in cardiac function. Little is known about how obesity during maturation affects the mechanical properties of the heart. The purpose of this study was to evaluate contractile properties in developing hearts from animals with dietary-induced obesity (high-fat high-sucrose diet (HFHS)). We hypothesized that obesity induced during adolescence results in decrements in cardiac contractile function. Three-week old rats (n=16) were randomized into control (chow) or dietary-induced obesity (HFHS) groups. Following 14 weeks on the diet, skinned cardiac trabeculae fibre bundle testing was performed to evaluate active and passive force, maximum shortening velocity, and calcium sensitivity. Rats in the HFHS group had significantly larger body mass and total body fat percentage. There were no differences in maximal active or passive properties of hearts between groups. Hearts from HFHS group rats had significantly slower maximum shortening and lower calcium sensitivity than controls. Decreased shortening velocity and calcium sensitivity in hearts of obese animals may constitute increased risk of cardiac disease in adulthood. Novelty Bullets • Cardiac muscle from animals exposed to an obesogenic diet during development had lower shortening velocity and calcium sensitivity than those from animals fed a chow diet. • These alterations in mechanical function may be a mechanism for the increased risk of cardiac disease observed in adulthood.
The effects of honey and cinnamonmixture on improving the quality of life in breast cancer

Introduction: Improving the quality of life in any patients suffering from cancer is regarded as the main goal of their treatment. The results of several studies have indicated that integration of complementary and alternative therapies with conventional therapy can improve the quality of life in breast cancer patients. In the present study, the effects of honey and cinnamon mixture on the quality of life in patients with breast cancer were investigated. Materials and Method: The present clinical trial study was performed on 119 women with breast cancer within the age range of 20-60, who referred to medical college pain and palliative care clinic due to their pain and to receive complementary therapy. Initially, the patients’ quality of life was specified using the EORTC QLQ-C30 questionnaire. Then, all the patients consumed a mixture of honey and cinnamon powder three times per day for one week. Patients with a history of allergy to honey and cinnamon , psychopathic disorders , recent chemotherapy or candidates of receiving chemotherapy in the following week of intervention were excluded from the study. At the end of treatment, the patients refilled the questionnaire out again and any improvements in patients ‘quality of life were analyzed by comparing patients’ quality of life before and after intervention. To perform the analyses, SPSS statistical software was used. Results: Two patients refused to participate in the study due to their lack of faith in the proposed treatment. Hence, only the data provided by117 patients was analyzed. The patients’ mean age was 48.58±7.6 years old. Their average weight and height were 52.81±5.4 kg and 159.09±7.3 cm, respectively. 78.6%of the patients were married, 83.8% had the education less than high school diploma, and 71.8% were house wives. The average number of patients’ off springs was 2.74±1.1. Only one patient was affected by bilateral breast cancer. In 62.4% the tumor was diagnosed post menopausally, 66.7% of tumors were in stage I and only 5 patients were in end stags. In 84.6% of cases, a surgical intervention was performed. Assessment of patients’ quality of life before and after intervention indicated significant improvements in 23 criteria; however, no significant improvements were observed in 7 criteria. Both overall health and quality of life improved significantly after treatment. Conclusion: Using honey and cinnamon mixture for one week can improve most of the criteria addressing the quality of life in women with breast cancer.
Rapid Diagnosis of Invasive Fungal Infections

Despite the availability of new antifungal drugs, the overall survival for immunocompromised patients with invasive fungal infections remains too low, with large variations according to underlying disease (Pasqualotto and Denning, 2005). Invasive fungal infections remain an important cause of morbidity and mortality. The most common fungi that cause disease in transplant recipients and other immunocompromised patients are Candida and Aspergillus species (Erjavec and Verweij, 2002). ISSN: 2319-7706 Volume 4 Number 11 (2015) pp. 470-486 http://www.ijcmas. com
Prevention of eating disorders: 2019 in review

ABSTRACT This article reviews 11 prevention-related publications in Eating Disorders: The Journal of Treatment & Prevention during 2019. Two models from the 2018 review continue to frame this analysis: (1) the Mental Health Intervention Spectrum from health promotion → types of prevention → case identification and referral → treatment; and (2) parsing phases of prevention into rationale, theory, and methodology → clarification of risk factors → implications for specific preventive interventions → design innovation and feasibility (pilot) research → efficacy and effectiveness research → program dissemination. These articles illustrate how the theoretical complexity and rigorous methodological demands of prevention science are manifest in the eating disorder field. A subset of articles also demonstrates the importance of working with researchers and community stakeholders to improve our understanding of how ethnicity, class, and gender intersect with planning for improvements in all phases of prevention. Other subsets show the need to expand the list of relevant risk factors, and how the traditional schema of masculinity creates both maladaptive biases in case identification and obstacles to an effective and compassionate understanding of EDs. Finally, implications of the absence of efficacy, effectiveness, and dissemination studies are discussed.
Factors Affecting Compliance Plan of Thalassemic Ch ildren and their Mothers in Outpatient Clinic at Zagazig University Hospitals

Children with thalassemia major must be treated wit h life-long blood transfusions. Evidence suggests t hat patients with more knowledge/information about thei r illnesses adhere more readily to treatment schedu les. However, there has been little evaluation of diseas e knowledge and treatment adherence in thalassemia major children. The objectives of the current study were to detect factors affecting the compliance of thala ssemic children and their mothers and to identify the rela tionships between disease knowledge and treatment a dherence in thalassemic children. A cross-sectional descript ive design and purposive sampling were used. fifty thalassemia major children (mean age 13.74 years) and their 50 mothers were recruited. structured questionnaire co nsisting of (A) personal Information; included, Socio-demogr aphic and disease-related data were collected which included age, gender, educational level, (b) An ass essment of disease knowledge about TM ; Assessment of disease knowledge of children and their mothers con sisted of 20 open questions measuring children's an d mothers' knowledge, treatment and compliance of tre atm nt plan about TM. The result of this study reve aled that that moderate commitment was apparent in 6% of sam ple with week knowledge and 60% of sample with moderate knowledge while, strong commitment was fou nd in 26% of sample with moderate knowledge and in 8% of them with week knowledge. This relation was h ighly statistically significant (p= .000). Based on the findings of the current study, it can be concluded that, The positive association between knowledge ab out disease and treatment adherence and factors of patients’ kn owledge indicate the need for systematic education for patients and caregivers to improve their compliance with treatment. The current study recommended that , t e improvement of the quality of patient care, reinfor cement of medical education and enhanced efforts by clinical staff to provide practical knowledge to children wi th thalassemia major and their parents is mandatory to significantly improve patient compliance to treatme nt.
Near-infrared Spectroscopy, Motor Cortex, Directional Arm Movements, Optical Imaging, Hemodynamic Response

This study aims at determining arm-movement directions from functional near-infrared spectroscopy (fNIRS) hemodynamic signals in order to decode intentional motor commands, originating in the motor cortices of humans, which could be implemented in neuroprosthetic assistive devices for assisting th e physically disabled. Motor cortical hemodynamic responses were recorded using 64 spatially distributed optrodes from 14 normal subjects during free arm orthogonal movements in the xand y-directions on a horizontal plane. The time course of oxy-(HbO2) and deoxy-hemoglobin (Hb), and of their summation (HbO2 + Hb) and difference (HbO2 – Hb) signals, representing the hemodynamic profiles of total oxygen delivery and ext raction, respectively, were computed for the localized neuronal populations in the motor cort ices underlying the optrodes . Analysis of the above hemodynamic signals revealed that they could be temporally, spatially, or spatiotemporally decoupled, depending on the movement d irection . Thus, by analyzing the spatiotemporal profiles of brain activation we could identify the direction of the orthogonal movements uniquely . Our findings demonstrate that movement direction, a key feature of motor commands, can be reliably extracted in real-time from surface recorded fNIRS signals, and support their viability in future noninvasive assistive devices.
FPGA - HARDWARE BASED DES & BLOWFISH SYMMETRIC CIPHER ALGORITHMS FOR ENCRYPTION & DECRYPTION OF SECURED WIRELESS DATA COMMUNICATION

: Now a days internet and wireless networks growing rapidly, information and network security becomes a vital process to protect commerce secret and evaluation privacy. Earlier security was a major issue for military applications but now a days the area of communication applications has been enhanced since most of the communication takes place over the web. Hence, the principal goal of any encryption algorithm is to provide security against any unauthorized attacks as well as to make communication network smoother without any hurdle. In this paper, we demonstrated performance of the most communication network data encryption algorithms: DES and Blowfish in terms of speed and power consumption. In this paper, we also demonstrated simulation results of DES encryption and decryption algorithm in VHDL coding with the help of Xilinx 9.2i ise and practical implementation of DES encryption and decryption algorithm in System C coding on FPGA - Spartan 3 XC3S200 with the help of Xilinx Platform Studio. We have also practically implemented Blowfish encryption and decryption algorithm in System C coding on FPGA - Spartan 3 XC3S200 with the help of Xilinx Platform Studio. We could also show that Blowfish encryption and decryption algorithm simulation results in VHDL coding with the help of Xilinx 9.2i ise in future. The study of DES and Blowfish algorithms shows that Blowfish algorithm runs faster than DES algorithm and the power consumption is almost same.
Forensic Investigation of User’s Web Activity on Google Chrome using various Forensic Tools

Summary Cyber Crimes are increasing day by day, ranging from confidentiality violation to identity theft and much more. The web activity of the suspect, whether carried out on computer or smart device, is hence of particular interest to the forensics investigator. Browser forensics i.e forensics of suspect’s browser history, saved passwords, cache, recent tabs opened etc. , therefore supply ample amount of information to the forensic experts in case of any illegal involvement of the culprit in any activity done on web browsers. Owing to the growing popularity and widespread use of the Google Chrome web browser, this paper will forensically analyse the said browser in windows 8 environment, using various forensics tools and techniques, with the aim to reconstruct the web browsing activities of the suspect. The working of Google Chrome in regular mode, private “Google Incognito Mode” and portable modes of operation is discussed at length in this paper.
Evaluation of Self Medication Pattern among undergraduate students in South India

Self medication can be defined as the use of medication by a patient of his own initiative or on the advice of a pharmacist or a lay person instead of consulting a medical practitioner. Self medication is common in developing countries. Knowledge of self medication is more important among medical students as they are the future prescribers. The World Health Organization has emphasized that self medication must be correctly taught and controlled. This was a crosssectional study in which a self-developed questionnaire related to various aspects of self-medication was used. Study population consisted of students who have completed 6 months of internship. A total of 239 students were given a questionnaire, out of which 220 completed the questionnaire. 82% of the students said they had self medicated in the last one year. Allopathic was the preferred system of medicine, 54% obtained the information from previous prescription. The most common reason for self medication did not spend money on doctors' fees (42.3%), the majority of the students (62.1%) opined that an adverse drug reaction is the major disadvantage. The four most common symptoms for which self medication was taken were fever (68.4%), headache (54.5%), cold/cough (48.2%) and musculoskeletal pain (40.2%). The prevailing self-medication practices were inappropriate in a substantial proportion of medical students with inadequate knowledge regarding appropriate drug choice, duration of treatment doses, and side effects. There is a need for rational educational interventions related to self-medication.
Bird’s Eye Review on Food Image Classification using Supervised Machine Learning

– Food image recognition and classification is a challenging task in image recognition. Due to a variety of food dishes available, it becomes a very complicated task to correctly classify the food image as belonging to one of the predefined classes. Significant work has been carried out on food recognition and classification using Computer Vision. Food recognition is important to assess diet of people with diabetics and people suffering from various food allergies. Food recognition also helps in finding the calorie value of foods, its nutrition value, food preferences etc. This survey paper covers some of the work done in food image recognition and classification using Deep Convolutional Neural Networks (DCNN) using various parameters and models, and other machine learning techniques. The classification accuracy of various models is also mentioned. The on-going work on Indian food image classification is also mentioned, which aims to improve the classification accuracy by choosing the suitable hyperparameters.
CHARACTERISTICS OF ANTIMICROBIAL PEPTIDES ORIGINATED FROM INVERTEBRATES INCLUDING INSECT

Sam Woong Kim 1 , Woo Young Bang 2 , Tae Wan Kim 1 , Seung-Ho Jeon 3 , Chi Won Noh 4 , Chae Won Lee 2 and * Il-Suk Kim 1 . 1. Department of Animal Resources Technology, Gyeongnam National University of Science and Technology, Gyeongnam, 52725, South Korea. 2. National Institute of Biological Resources (NIBR), Environmental Research Complex, Incheon 22689, South Korea. 3. Department of Agronomy & Medicinal Plant Resources, Gyeongnam National University of Science and Technology, Jinju, 52725, South Korea. 4. Gyeongsangnam-do Agricultural Research & Extension Services, Jinju, 52733, South Korea. Manuscript Info Abstract . Manuscript History
Initial Hemodynamic Profiles of Children with Dengue Shock Syndrome in Referral Settings

Background: Fluid therapy for dengue shock syndrome (DSS) requires a dynamic approach that involves monitoring of the pathophysiological processes as well as the preload, contractility, and afterload assessment during the course dengue infection. Hemodynamically unstable DSS patients received in referral setting often complicated by fluid overload and secondary infection. Objective: This study aims to provide hemodynamic profiles and fluid responsiveness of pediatric patients admitted to the PICU with DSS. Methods: Hemodynamic profiles, laboratories, and demographic data were collected from patients aged 1 month to 18 years old with DSS who were admitted to the Pediatric Intensive Care Unit (PICU) at Dr. Sardjito General Hospital, Yogyakarta, Indonesia from January to December 2016. Hemodynamic profiles were assessed in clinically shock and not clinically shock group at PICU admission using the non-invasive Ultrasonic Cardiac Output Monitor (USCOM). Fluid responsiveness in clinically shock group was evaluated after fluid challenge with 10 ml/kgBW crystalloid or colloid. Results: Eighty six subjects were included in this study. Sixty six subjects were admitted to PICU with clinically shock condition. This group received less intravenous fluid than hemodynamically stable group (6.9 vs 7.52 ml/kgBW/hour respectively), had higher mean hematocrit level (42.09% vs 40.32% respectively), had higher hematocrit level during PICU stay (43.37% vs 42.06% respectively), significantly higher percentage to receive inotropes agent (62,1% vs 5%, p 0,000) and longer duration of inotropes usage (23,5 vs 0 hours, p 0.72). From the clinically shock patients admitted to PICU, only 19,69% were fluid responsive. Other subjects in this group with fluid non responsive state, 90,38% had low inotropic index and high systemic vascular resistance index. Among 8 patients in clinically shock group who died during PICU stay, 6 of them had low cardiac Index, fluid non responsive condition, low inotropic index and high systemic vascular resistance index. Conclusion: Only a small percentage of DSS patients with clinically shock admitted to the PICU were fluid responsive. Majority of DSS cases in children had low inotropy index and high systemic vascular resistance index.
Study of Frequency Distribution of Corrosive Poisoning Cases Among Females with Special Reference to Dowry Deaths

Introduction: Caustics cause both clinical and histological damage on contact with tissue surfaces. Caustics exist in both solid and liquid forms, with differences in viscosity, concentration of solution, and pH. An acid is a chemical substance whose aqueous solutions are characterized by a sour taste and their ability to turn blue litmus to red and which causes marked injury, when the pH is below 3. The amount of injury depends on time of contact, strength of the substance to penetrate tissues; volume, pH, and concentration; stomach contents; and titratable acid reserve. The aim of this study is to analyse the incidence of corrosive poisons, incidence of corrosive poisoning among the age and sex distribution, incidence of corrosive poisoning among married females. Material and methods: The study was carried on at Mortuary of Osmania General Hospital during 2003-2006. During this period 1135 cases of various poisoning deaths were registered. Among them 62 deaths were due to corrosive poisoning. All the reported cases in the study period were investigated. Results: A study of 1135 cases of various poisoning during 2003-2006, of which 62 corrosive poisoning fatalities. Among the 62 deaths caused due to corrosive poisoning 27 cases were of females who constituted 43.5% of cases of death due to corrosive acid poisoning. 9 dowry deaths were due to corrosive poisoning. Conclusion: The incidence of corrosive poisoning is found to be higher and among married women. Corrosives are more often the choice of poison due to its ease of access.
BONE MARROW ANGIOGENESIS AND MICROVESSEL DENSITY IN PATIENTS WITH

Introduction: anemia (AA) according to the severity as non severe (NsAA), severe (sAA) and very severe (VsAA) and to study microvessel density using immunohistochemical stain using CD 34 an analysis of microvessel density by computer assisted quantitative analyser and to compare it in the three subcategories of aplastic anemia with control group. prospective study was conducted in the Departmen Thirty cases of AA patients and 10 cases of control were taken. AA patients were diagnosed on the basis of complete blood count, peripheral blood smear, bone marrow aspiration examination and bone marrow tre VsAA using camitta et al criteria. IHC using CD 34 was performed to look for angiogenesis and to calculate microvessel density (MVD). and 3rd decade of life. Females were more commonly affected with a male to female ratio (11/19) of 0.58:1. In Aplastic anemia patients (Group I), using Camitta et al criteria 30 cases were categorized into NsAA (10 cases), sAA (12 cases) and is a good marker of angiogenesis. MVD showed a decreasing trend with increase in severity of the disease. angiogenesis and mean MVD score shows a decreasing trend from anemia