Miracle-dz/UniFAR-FTUs huggingface dataset:
An Overview of the Application of Harmony Search for Chemical Engineering Optimization

Harmony search algorithm and its variants have been used in several applications in medicine, telecommunications, computer science, and engineering. This article reviews the global and multi-objective optimization for chemical engineering using harmony search. The main features of the HS method and several of its popular variants and hybrid versions including their relevant algorithm characteristics are described and discussed. A variety of global and multi-objective optimization problems from chemical engineering and their resolution using HS-based methods are also included. These problems involve thermodynamic calculations (phase stability analysis, phase equilibrium calculations, parameter estimation, and azeotrope calculation), heat exchanger design, distillation simulation, life cycle analysis, and water distribution systems, among others. Remarks on future developments of HS and its related algorithms for global and multi-objective optimization in chemical engineering are also provided in this review. HS is a reliable and promising stochastic optimizer to resolve challenging global and multi-objective optimization problems for process systems engineering.
AN XMM-NEWTON SURVEY OF THE SOFT X-RAY BACKGROUND. III. THE GALACTIC HALO X-RAY EMISSION

We present measurements of the Galactic halo's X-ray emission for 110 XMM-Newton sight lines selected to minimize contamination from solar wind charge exchange emission. We detect emission from few million degree gas on ∼4/5 of our sight lines. The temperature is fairly uniform (median = 2.22 × 106 K, interquartile range = 0.63 × 106 K), while the emission measure and intrinsic 0.5–2.0 keV surface brightness vary by over an order of magnitude (∼(0.4–7) × 10−3 cm−6 pc and ∼(0.5–7) × 10−12 erg cm−2 s−1 deg−2, respectively, with median detections of 1.9 × 10−3 cm−6 pc and 1.5 × 10−12 erg cm−2 s−1 deg−2, respectively). The high-latitude sky contains a patchy distribution of few million degree gas. This gas exhibits a general increase in emission measure toward the inner Galaxy in the southern Galactic hemisphere. However, there is no tendency for our observed emission measures to decrease with increasing Galactic latitude, contrary to what is expected for a disk-like halo morphology. The measured temperatures, brightnesses, and spatial distributions of the gas can be used to place constraints on models for the dominant heating sources of the halo. We provide some discussion of such heating sources, but defer comparisons between the observations and detailed models to a later paper.
Predictions for √{s NN }=5.02 TeV Pb + Pb collisions from a multiphase transport model

We present predictions from the string melting version of a multi-phase transport model on various observables in Pb+Pb collisions at $\sqrt {s_{NN}}=5.02$ TeV. We use the same version of the model as an earlier study that reasonably reproduced dN/dy, $p_{\rm T}$-spectra and elliptic flow of charged pions and kaons at low-$p_{\rm T}$ for central and semi-central heavy ion collisions at 200 GeV and 2.76 TeV. While we compare with the already-available centrality dependence data on charged particle $dN/d\eta$ at mid-pseudorapidity in Pb+Pb collisions at 5.02 TeV, we make predictions on identified particle dN/dy, $p_{\rm T}$-spectra, azimuthal anisotropies $v_n (n=2,3,4)$, and factorization ratios $r_{n}(\eta^{a},\eta^{b}) (n=2,3)$ for longitudinal correlations.
Blue wings and bumps via Fermi-like acceleration of Ly α photons across shocks

We explore the impact of Fermi-like acceleration of Lyman-alpha (Ly{\alpha}) photons across shock fronts on the observed Ly{\alpha} spectral line shape. We first confirm the result of Neufeld & McKee (1988) that this mechanism gives rise to extended blue wings which may have been observed in some radio galaxies. Our Monte-Carlo radiative transfer calculations further show that in a minor modification of the shell-model, in which we add an additional static shell of hydrogen, this process can naturally explain the small blue bumps observed in a subset of Ly{\alpha} emitting galaxies, which have been difficult to explain with conventional shell-models. Blue bumps can be produced with an additional column density of static hydrogen as small as $N_{HI}^{static} \ll N_{HI}^{shell}$, and typically occur at roughly the outflow velocity of the shell. In our model the spectra of so-called 'blue-bump objects' might reflect an evolutionary stage in which the outflows regulating the escape of Ly{\alpha} photons are still engulfed within a static interstellar medium.
The lensing efficiencies of MACS X-ray-selected versus RCS optically selected galaxy clusters

The statistics of strongly lensed arcs in samples of galaxy clusters provide information on cluster structure that is complementary to that from individual clusters. However, samples of clusters that have been analysed to date have been either small, heterogeneous or observed with limited angular resolution. We measure the lensed-arc statistics of 97 clusters imaged at high angular resolution with the Hubble Space Telescope, identifying lensed arcs using two automated arc-detection algorithms. The sample includes similar numbers of X-ray-selected [MAssive Cluster Survey (MACS)] and optically selected [Red-Sequence Cluster Survey (RCS)] clusters, and spans cluster redshifts in the range 0.2 < z < 1. We compile a catalogue of 42 arcs in the X-ray-selected subsample and seven arcs in the optical subsample. All but five of these arcs are reported here for the first time. At 0.3 ≤ z ≤ 0.7, the X-ray-selected clusters have a significantly higher mean frequency of arcs, 1.2 ± 0.2 per cluster, versus 0.2 ±0.1 in the optical sample. The strikingly different lensing efficiencies indicate that X-ray clusters trace much larger mass concentrations, despite the similar optical luminosities of the X-ray and optical clusters. The mass difference is supported also by the lower space density of the X-ray clusters and by the small Einstein radii of the few arcs in the optical sample. Higher order effects, such as differences in concentration or substructure, may also contribute.
The impact of the COVID-19 lockdown on birthweight among singleton term birth in Denmark

In Denmark, a nationwide COVID-19 lockdown was implemented on March 12, 2020 and eased on April 14, 2020. The COVID-19 lockdown featured reduced prevalence of extremely preterm or extremely low birth weight births. Here we explore the impact of this COVID-19 lockdown on term birth weights in Denmark. We conducted a nationwide register-based cohort study on 27,870 live singleton infants, born at term (weeks 37-41), between March 12 and April 14, 2015-2020, using data from the Danish Neonatal Screening Biobank. Primary outcomes, corrected for confounders, were birth weight, small-for-gestational-age (SGA), and large-for-gestational-age (LGA), comparing the COVID-19 lockdown to the previous five years. Data were analysed using linear regression to assess associations with birth weight. Multinomial logistic regression was used to assess associations with size-for-gestational-age (xGA) categories. Adjusted mean birth weight was significantly increased by 16.9 g (95% CI = 4.1 - 31.3) during the lockdown period. A dip in mean birth weight was found in gestational weeks 37 and 38 balanced by an increase in weeks 40 and 41. The 2020 lockdown period was associated with an increased LGA prevalence (aOR 1.13, 95% CI = 1.05 - 1.21). No significant changes in proportions of xGA groups were found between 2015 and 2019. Conclusion: The nationwide COVID-19 lockdown resulted in a small but significant increase in birth weight and proportion of LGA infants, driven by an increase in birth weight in gestational weeks 40 and 41.
Knowledge, attitudes and practices of cervical cancer screening among rural women in KwaZulu-Natal, South Africa

Introduction cervical cancer continues to be a major cause of morbidity and mortality among women in the developing world. Despite the national cervical cancer screening programme, findings show low levels of knowledge and practices of cervical cancer screening among rural women in South Africa (SA). The purpose of this study was to determine the knowledge, attitudes and practices of cervical cancer screening among rural women in KwaZulu-Natal, SA. Methods an observational cross-sectional study was performed. The study was conducted at three rural clinics. A systematic sampling technique was used to select 283 women, aged 18-65 years. Data were collected using a standardised structured self-administered questionnaire. Data were analysed using descriptive and analytic statistics. Results findings showed a high level of awareness of cervical cancer (93.3%, n=264) and the Pap smear test (95.1%, n=269). Knowledge of cervical cancer-associated factors, symptoms, screening methods and treatment was poor (28.0%, n=79). An overwhelming majority (81.8%, n=231) displayed a positive attitude towards cervical cancer screening. The practice of cervical cancer screening was fairly good (66.8%, n=189). The results showed that socio-demographics were not statistically significantly associated with knowledge of cervical cancer and cervical cancer screening. Conclusion despite the inadequate knowledge of women, attitudes towards cervical cancer and screening were generally positive. Health care practitioners are encouraged to focus not only on creating awareness but also on improving knowledge so as women will not only undergo screening but appreciate the importance of cervical cancer screening.
Electron-impact excitation of diatomic hydride cations – I. HeH+, CH+, ArH+

{\bf R}-matrix calculations combined with the adiabatic nuclei approximation are used to compute electron-impact rotiational excitation rates for three closed-shell diatomic cations, HeH$^+$, CH$^+$, ArH$^+$. Comparisons with previous studies show that an improved treatment of threshold effects leads to significant changes in the low temperature rates, furthermore the new calculations suggest that excitation of CH$^+$ is dominated by $\Delta J =1$ transitions as is expected for cations with a large dipole moment. A model for ArH$^+$ excitation in the Crab Nebula is presented which gives results consistent with the observations for electron densities in the range $2-3\times 10^3$~cm$^{-3}$.
Inertial Focusing in Spiral Microchannels

The ability to control and manipulate the motion of particles or bio-cells from a complex mixture has been the center of attention since the beginning of microfluidics. The microfluidics community has always strived to develop miniaturized ‘lab on chip’ devices to achieve fastest and most accurate size based separation of cells from given bio-sample. While in last few years, people have come up with different solutions like electrophoresis, magnetophoresis, etc.; but most of them rely on low Reynolds number operation and hence increase the overall processing time of the sample. The recent development in the field of inertial microfluidics can be the answer to this problem. The present thesis is based on the experimental study of the dynamics of the particle focusing behavior in spiral microchannels in inertial flow regime. The effect of some of the critical geometrical parameters like width of the channel cross-section (Dh), particle confinement ratio (λ) and some of the flow parameters like channel Reynolds number (Rec) and Dean number (De) on the focusing behavior of particles in spiral channels is studied. Based on the new understanding, a design rule for is put forward to achieve separation of particles in spiral microchannels in a single pass. Lastly, an experimental study is performed to understand the effect of aspect ratio of the cross-section on the focusing of particles in spiral microchannels. This new understanding of high throughput inertial focusing of particles in spiral microchannels is another step forward towards the development of ‘lab on chip’ devices to achieve separation in one pass and towards the development of a theory explaining the focusing of particles in inertial flow regime.
Excitations of optically driven atomic condensate in a cavity: theory of photodetection measurements

Recent experiments have demonstrated an open system realization of the Dicke quantum phase transition in the motional degrees of freedom of an optically driven Bose–Einstein condensate in a cavity. Relevant collective excitations of this light–matter system are polaritonic in nature, allowing access to the quantum critical behavior of the Dicke model through light leaking out of the cavity. This opens the path to using photodetection-based quantum optical techniques to study the dynamics and excitations of this elementary quantum critical system. We first discuss the photon flux observed at the cavity face and find that it displays a different scaling law near criticality than that obtained from the mean-field theory for the equivalent closed system. Next, we study the second-order correlation measurements of photons leaking out of the cavity. Finally, we discuss a modulation technique that directly captures the softening of polaritonic excitations. Our analysis takes into account the effect of the finite size of the system, which may result in an effective symmetry-breaking term.
DEMONSTRATING DIVERSITY IN STAR-FORMATION HISTORIES WITH THE CSI SURVEY

We present coarse but robust star-formation histories (SFHs) derived from spectrophotometric data of the Carnegie-Spitzer-IMACS Survey, for 22,494 galaxies at with stellar masses of 109 M⊙ to 1012 M⊙. Our study moves beyond “average” SFHs and distribution functions of specific star-formation rates (sSFRs) to individually measured SFHs for tens of thousands of galaxies. By comparing star-formation rates (SFRs) with timescales of , and 108 years, we find a wide diversity of SFHs: “old galaxies” that formed most or all of their stars early, galaxies that formed stars with declining or constant SFRs over a Hubble time, and genuinely “young galaxies” that formed most of their stars since z = 1. This sequence is one of decreasing stellar mass, but remarkably, each type is found over a mass range of a factor of 10. Conversely, galaxies at any given mass follow a wide range of SFHs, leading us to conclude that (1) halo mass does not uniquely determine SFHs, (2) there is no “typical” evolutionary track, and (3) “abundance matching” has limitations as a tool for inferring physics. Our observations imply that SFHs are set at an early epoch, and that—for most galaxies—the decline and cessation of star formation occurs over a Hubble time, without distinct “quenching” events. SFH diversity is inconsistent with models where galaxy mass, at any given epoch, grows simply along relations between SFR and stellar mass, but is consistent with a two-parameter lognormal form, lending credence to this model from a new and independent perspective.
Real-world Clinical Outcomes of Bebtelovimab and Sotrovimab Treatment of High-risk Persons With Coronavirus Disease 2019 During the Omicron Epoch

Abstract Background Antispike monoclonal antibodies are recommended for early treatment of high-risk persons with mild to moderate coronavirus disease 2019 (COVID-19). However, clinical outcomes of their use during the severe acute respiratory syndrome coronavirus 2 Omicron wave are limited. Methods This is a descriptive retrospective study of high-risk adult patients who received treatment with sotrovimab (January 1–March 20, 2022) or bebtelovimab (March 21–April 30, 2022). The primary outcome was the proportion of patients who progressed to severe outcome within 30 days after receiving antispike-neutralizing monoclonal antibody infusion. Results A total of 3872 high-risk patients (median age, 62.7 years; 41.1% male) with mild to moderate COVID-19 received sotrovimab (n = 2182) or bebtelovimab (n = 1690). Among sotrovimab-treated patients, the most common comorbidities were an immunosuppressed condition (46.7%), hypertension (38.2%), and diabetes (21.2%). The rates of severe outcome, intensive care unit (ICU) admission, and mortality were 2.2%, 1.0%, and 0.4%, respectively, after sotrovimab infusion. Among bebtelovimab-treated patients, the most common comorbidities were hypertension (42.7%), diabetes (17.1%), and an immunosuppressed condition (17.0%). The rates of severe disease, ICU admission, and mortality were 1.3%, 0.5%, and 0.2%, respectively, after bebtelovimab infusion. Older age, immunosuppressed status, and several comorbidities were associated with severe disease progression, while COVID-19 vaccination was associated with lower risk. No anaphylaxis was reported during monoclonal antibody infusion. Conclusions This real-world analysis of a large cohort of high-risk patients demonstrates low rates of severe disease after treatment with sotrovimab during the era dominated by Omicron B.1. 1.529 and after treatment with bebtelovimab during the era dominated by BA.2 and Omicron subvariants.
EVIDENCE FOR UBIQUITOUS COLLIMATED GALACTIC-SCALE OUTFLOWS ALONG THE STAR-FORMING SEQUENCE AT z ∼ 0.5

We analyze Mg ii λλ2796, 2803 and Fe ii λλ2586, 2600 absorption profiles in individual spectra of 105 galaxies at 0.3 < z < 1.4. The galaxies, drawn from redshift surveys of the GOODS fields and the Extended Groth Strip, sample the range in star formation rates (SFRs) occupied by the star-forming sequence with stellar masses log M*/M☉ ≳ 9.6 down to SFR ≳ 2 M☉ yr−1 at 0.3 < z < 0.7. Using the Doppler shifts of Mg ii and Fe ii absorption as tracers of cool gas kinematics, we detect large-scale winds in 66 ± 5% of the galaxies. Hubble Space Telescope Advanced Camera for Surveys imaging and our spectral analysis indicate that the outflow detection rate depends primarily on galaxy orientation: winds are detected in ∼89% of galaxies having inclinations (i) <30° (face-on), while the wind detection rate is ∼45% in objects having i > 50° (edge-on). Combined with the comparatively weak dependence of wind detection rate on intrinsic galaxy properties, this implies that biconical outflows are ubiquitous in normal, star-forming galaxies at z ∼ 0.5. We find that wind velocity is correlated with galaxy M* at 3. 4σ significance, while outflow equivalent width is correlated with SFR at 3. 5σ significance, suggesting hosts with higher SFR launch more material and/or generate a larger velocity spread for the absorbing clouds. Assuming the gas is driven into halos with isothermal density profiles, the wind velocities (∼200–400 km s−1) permit escape from the halo potentials only for the lowest-M* systems in the sample. However, the gas carries sufficient energy to reach distances ≳ 50 kpc, and may therefore be a viable source of material for the massive, cool circumgalactic medium around bright galaxies at z ∼ 0.
The effect of interacting dark energy on local measurements of the Hubble constant

In the current state of cosmology, where cosmological parameters are being measured to percent accuracy, it is essential to understand all sources of error to high precision. In this paper we present the results of a study of the local variations in the Hubble constant measured at the distance scale of the Coma Cluster, and test the validity of correcting for the peculiar velocities predicted by gravitational instability theory. The study is based on N-body simulations, and includes models featuring a coupling between dark energy and dark matter, as well as two ΛCDM simulations with different values of σ8. It is found that the variance in the local flows is significantly larger in the coupled models, which increases the uncertainty in the local measurements of the Hubble constant in these scenarios. By comparing the results from the different simulations, it is found that most of the effect is caused by the higher value of σ8 in the coupled cosmologies, though this cannot account for all of the additional variance. Given the discrepancy between different estimates of the Hubble constant in the universe today, cosmological models causing a greater cosmic variance is something that we should be aware of.
Contact allergy to metals in metalworkers: A systematic review and meta‐analysis

Occupational hand eczema is frequent in metalworkers. The contribution of metal allergies is poorly elucidated even though such exposures are common at the workplace. To estimate the prevalence of metal allergy to cobalt (Co), chromium (Cr) and nickel (Ni) in metalworkers and compare these to estimates from the European Surveillance System on Contact Allergies (ESSCA). Two authors independently searched PubMed for studies reporting on the prevalence of metal allergy in metalworkers. Proportion meta‐analyses were performed to calculate the pooled proportions of metal allergy in metalworkers. In total, 29 studies (22 from Europe) were included yielding 5691 subjects for quantitative analysis. The pooled proportion (95% confidence interval) of Co, Cr and Ni in European metalworkers with dermatitis referred to patch test clinics was 8.2% (5.3%–11.7%), 8.0% (5.1%–11.4%), and 11.0% (7.3%–15.4%), respectively. The corresponding estimates for unselected metalworkers from workplace studies were 4.9% (2.4%–8.1%), 5.2% (1.0%–12.6%), and 7.6% (3.8%–12.6%), respectively. In comparison, the prevalence of metal allergy in 13 382 consecutive European males with dermatitis was 3.9% (3.6%–4.2%), 4.4% (4.1%–4.8%) and 6.7% (6.3%–7.0%) for Co, Cr and Ni, respectively. Data on sex, age, body piercings and atopic dermatitis in metalworkers with metal allergy was mostly lacking. Metal allergy to all three metals was significantly more common in European metalworkers with dermatitis attending patch test clinics as compared to ESSCA data, indicating a relationship to occupational exposures, however, confounders could not be accounted for.
Biomarkers of potential harm in people switching from smoking tobacco to exclusive e‐cigarette use, dual use or abstinence: secondary analysis of Cochrane systematic review of trials of e‐cigarettes for smoking cessation

Abstract Aims This study aims to compare biomarkers of potential harm between people switching from smoking combustible cigarettes (CC) completely to electronic cigarettes (EC), continuing to smoke CC, using both EC and CC (dual users) and using neither (abstainers), based on behaviour during EC intervention studies. Design Secondary analysis following systematic review, incorporating inverse variance random‐effects meta‐analysis and effect direction plots. Setting This study was conducted in Greece, Italy, Poland, the United Kingdom and the United States. Participants A total of 1299 adults smoking CC (nine studies) and provided EC. Measurements Measurements were conducted using carbon monoxide (CO) and 26 other biomarkers. Findings In pooled analyses, exhaled CO (eCO) was lower in EC versus EC + CC [mean difference (MD) = −4.40 parts per million (p.p.m.), 95% confidence interval (CI) = −12.04 to 3.24, two studies] and CC (MD = −9.57 p.p.m., 95% CI = −17.30 to −1.83, three studies). eCO was lower in dual users versus CC only (MD = −1.91 p.p.m., 95% CI = −3.38 to −0.45, two studies). Magnitude rather than direction of effect drove substantial statistical heterogeneity. Effect direction plots were used for other biomarkers. Comparing EC with CC, 12 of 13 biomarkers were significantly lower in EC users, with no difference for the 13th. Comparing EC with dual users, 12 of the 25 biomarkers were lower for EC, and five were lower for dual use. For the remaining eight measures, single studies did not detect statistically significant differences, or the multiple studies contributing to the outcome had inconsistent results. Only one study provided data comparing dual use with CC; of the 13 biomarkers measured, 12 were significantly lower in the dual use group, with no statistically significant difference detected for the 13th. Only one study provided data on abstainers. Conclusions Switching from smoking to vaping or dual use appears to reduce levels of biomarkers of potential harm significantly.