Miracle-dz/UniFAR-FTUs huggingface dataset:
Extremity Exercise Program in Breast Cancer Survivors Suffering from Chemotherapy-Induced Peripheral Neuropathy: A Feasibility Pilot Study

Objectives: To evaluate the feasibility of implementation of an extremity exercise program and to examine its preliminary effects in breast cancer survivors suffering from chemotherapy-induced peripheral neuropathy (CIPN). Sample & Setting: Thirteen breast cancer survivors from one hospital in northern Taiwan. Methods and Variables: A single group with repeated measures, and a quasi-experimental design. The intervention program was a four week, home-based extremity exercise program that was comprised of 10 skilled hand exercises and Buerger-Allen exercises. The Total Neuropathy Scale (clinical version), Functional Assessment of Cancer Therapy/Gynecologic Oncology Group, Neurotoxicity (13-Item Version), Identification Pain Questionnaire, and pain Visual Analogue Scale were used to measure CIPN before exercise (T1), during (T2~T4), and after exercise (T5). Qualitative data were also collected at each time point. Data were analyzed by using descriptive statistics, generalized estimating equations, and directed content analysis. Results: None of the participants reported adverse events during the study period. The extremity exercise program significantly improved patient-reported CIPN after intervention at T4 or T5 but was insignificant on clinician-assessed CIPN. The qualitative data of participant experience indicated that this program is feasible and easy to follow. Conclusion: The extremity exercise program is feasible but needs to increase the sample size and prolong the intervention period for confirmation.
Dynamic Responses of Ballastless High-Speed Railway Due to Train Passage With Excitation of Uneven Trackbed Settlement

The ballastless slab track has been widely used in newly-developed high-speed railways in China as well as in other countries for its high stability and low maintenance. However, loss of track vertical alignment due to uneven trackbed settlement will bring adverse impact on train’s running safety and track serviceability. In this study, a train-track-trackbed coupling model has been proposed to investigate the dynamic responses of track structure with the excitation of trackbed settlement with varied patterns. To validate the proposed analysis model, comparisons with both the analytical solution and in- situ measures have been performed. The influences of train speeds, settlement trough amplitude and length are discussed based on this analysis model. It’s indicated that the dynamic responses of train vehicle and track structure increase with increasing in train speed and settlement amplitude within certain settlement length. By introducing the standards for train operation safety and riding comfort, a new trackbed settlement control criteria is proposed. The computation results indicate that the standard for train operation safety is found to be the dominating factor for uneven settlements with the length less than 10 m, while the standard for riding comfort dominates the settlement control criteria in other cases. To further facilitate the settlement control criteria in engineering practices, the ratio of settlement amplitude and settlement length (which is defined as deflection ratio) is adopted to depict the envelop curves for various settlement patterns.
Understanding social class in place: Responding to supergentrification in Aspen, Colorado

Existing research portrays elite places as prone to exclusion, welcoming of upscaling, and focused on protecting their economic self-interests. This paper provides nuance to this research by exploring how stakeholders understand and respond to supergentrification. During the fall of 2016, a group of citizen activists in the exclusive community of Aspen, Colorado, initiated an ordinance seeking to limit the expansion of luxury chain stores. Drawing on qualitative data related to this case, we show that how communities respond to supergentrification depends on locally specific understandings of place and social class, and how class interests have been institutionalized in local policies. In Aspen, residents opposed luxury chain stores by marshaling narratives that foreground the community's history of class mixing and the significance of working locals. Elected officials responded by taking account of the political power of local residents as well as the city's dependence on tax revenues from affluent visitors and second homeowners. Our findings extend and complicate understandings of how power works in elite places, highlighting both the potential for, and limitations of, efforts to thwart supergentrification and associated dislocation.
Variation in patient information and rehabilitation regimens after flexor tendon repair in the United Kingdom

Introduction There is clinical uncertainty regarding the optimal method of rehabilitation following flexor tendon repair. Many splint designs and rehabilitation regimens are reported in the literature; however, there is insufficient evidence to support the use of any one regimen. The aim of this study was to describe rehabilitation guidelines used in the United Kingdom (UK) following zone I/II flexor tendon repair. Methods Using a cross-sectional design, hand units in the UK were invited to complete a short survey and to upload their flexor tendon rehabilitation guidelines and patient information material. Approval was granted by the British Association of Hand Therapists. Data were extracted in duplicate, using a pre-piloted form, and analysed using descriptive statistics. Results Thirty-five hand units responded (21%), providing 52 treatment guidelines. Three splinting regimens were described, and all involved early active mobilisation: (i) long dorsal-blocking splint (DBS); (ii) short DBS; and (iii) relative motion flexion splint. Duration of full-time splint wear ranged from 4 to 6 weeks. There were variations in splint design and composition of home exercise programmes, particularly for the long DBS. Where reported, recommended return to driving ranged from 8 to 12 weeks, and return to light work activities ranged from 5 to 10 weeks. Discussion Treatment guidelines varied across UK hand therapy departments, suggesting that patients receive differing advice about how to protect, move and use their hand after zone I/II flexor tendon repair. The disparity in splint wear duration, home exercise frequency and prescribed functional restrictions raises potential financial and social implications for patients. Future research should explore rehabilitation burden in addition to clinical outcomes.
Impact of Liver Fibrosis on Survival of Patients with Intrahepatic Cholangiocarcinoma Receiving Gemcitabine-Based Chemotherapy

Intrahepatic cholangiocarcinoma (iCCA) is the most frequent subtype of cholangiocarcinoma (CCA), and the incidence has globally increased in recent years. In contrast to surgically treated iCCA, data on the impact of fibrosis on survival in patients undergoing palliative chemotherapy are missing. We retrospectively analyzed the cases of 70 patients diagnosed with iCCA between 2007 and 2020 in our tertiary hospital. Histopathological assessment of fibrosis was performed by an expert hepatobiliary pathologist. Additionally, the fibrosis-4 score (FIB-4) was calculated as a non-invasive surrogate marker for liver fibrosis. For overall survival (OS) and progression-free survival (PFS), Kaplan–Meier curves and Cox-regression analyses were performed. Subgroup analyses revealed a median OS of 21 months (95% CI = 16.7–25.2 months) and 16 months (95% CI = 7.6–24.4 months) for low and high fibrosis, respectively (p = 0.152). In non-cirrhotic patients, the median OS was 21.8 months (95% CI = 17.1–26.4 months), compared with 9.5 months (95% CI = 4.6–14.3 months) in cirrhotic patients (p = 0.007). In conclusion, patients with iCCA and cirrhosis receiving palliative chemotherapy have decreased OS rates, while fibrosis has no significant impact on OS or PFS. These patients should not be prevented from state-of-the-art first-line chemotherapy.
Integrated Farming System: A Tool for Doubling Farmer’s Income

Integrated Farming System is a holistic approach in which different enterprises are utilized in a collaborative way, wherein the resources are managed efficiently so that waste output of one enterprise serves as the input for another. Due to an ever-increasing population, the arable land is becoming increasingly scarcer per person, leaving little room for horizontal agricultural expansion. There are 115 million working farms in India, with about 80% of them being small or marginal farmers. With Integrated Farming System, the living standards of these farmers can be enhanced by efficient utilization of different enterprises. The IFS is actually a mixed farming system wherein different enterprises like dairy, fish, poultry, and other beneficial enterprises give an enhanced returns with lower risks, which can intermediate the losses of crops in case of severe climatic conditions. Under IFS, various enterprises having lower dependency on severe weather circumstances, the farmer is comparatively on safer side as far as the adversities of crop losses are concerned There are many advantages to integrated farming systems (IFS), such as a more efficient use of farm resources and an eco-friendlier strategy to farming. As a system of crop and livestock farming, IFS consists of at least two distinct but logically interdependent parts. Water efficiency, weed and pest control, and soil health can all be improved with IFS. It also helps to maintain water quality. Chemical fertilisers, weed killers, and pesticides should be used sparingly in an integrated farming system in order to protect the environment from their harmful effects. Adopting an Integrated Farming System (IFS) ensures a stable and long-term source of farm income by integrating a number of businesses to make the most of the land's natural resources. IFS itself is important for sustainable development of farmer by improving yield, economic return, employment generation, nutritional security and livelihood.
Practice of Music Therapy for Autistic Children Based on Music Data Mining

For children with autism, music therapy has aroused great concern with its novelty and better influence. Music therapy, as one of the effective treatment methods, has an important influence on the social interaction, behavior, and emotion of autistic children. This study attempts to explore a form of applying highly specialized impromptu music therapy to the personal treatment of autistic children in schools for the disabled, as well as the design method of specific music activities. Based on music data mining, the machine learning method is introduced to model music emotion features, and various algorithms are compared to find a model with higher recognition rate, and, at the same time, the antinoise ability and generalization ability of the model are further improved. Finally, a music emotion cognitive model with better performance is established. The results show that the model can effectively promote the overall development of autistic children’s cognitive movement, social communication, language communication, and cognition.
Real-World Cataract Surgery Complications and Secondary Interventions Incidence Rates: An Analysis of US Medicare Claims Database

Purpose To characterize cataract patients and postoperative outcomes in the Medicare fee-for-service (FFS) population. Design A retrospective observational cohort study. Methods Medicare fee-for-service (A&B) databases were queried from October 2015 to December 2017. Patients with procedural claims using CPT codes (66982 or 66984) and with 1–12 months of postcataract follow-up data were included in the analysis. Results 133,896 records of 82,246 CMS FFS claims were included in the analysis. The average patient age was 73.8, and 58.2% were females. The cataract surgery setting was ASC (71.3%) followed by HOPD (27.6%). The median time between first and second surgery was 15 days. The most common comorbidities included diabetes (28.6%), glaucoma (22.1%), and macular degeneration (21.7%). Posterior capsule rupture occurred in 0.2% of cases. The <6 months cumulative incidence of most common secondary surgical interventions was 4.7%, 0.2%, and 0.2% for Nd:YAG capsulotomy, IOL exchange, and IOL repositioning, respectively. Discussion. Real-world complication rates of cataract surgery may help reduce postcataract complications and procedure burden. Synopsis for Table of Contents. This study focused on a sample of the US Medicare beneficiary cataract population and describes its demographic characteristics and reports the cumulative incidence of common postcataract surgery complications and secondary surgical interventions (SSI).
Application of the Kvaal Method in Age Estimation of the Serbian Population Based on Dental Radiographs

This study aimed to evaluate the applicability of the Kvaal method in determining the age of a Serbian population. In this retrospective descriptive study, 170 dental patients (age range 16–77 years) were included. The measurements of six types of teeth were performed on digital orthopantomography radiographs according to the Kvaal method. Statistical inter-observer and intra-observer reliabilities were calculated to evaluate the reproducibility of the measurements, as well as to examine the correlation between chronological age and measured values. The evaluation revealed a substantial difference (over 12 years) between chronological and estimated age. The P ratio had the strongest correlation with chronological age for the maxillary central (r = ±0.293) and lateral incisors (r = ±0.240), whereas the pulp/root width ratio at level A had the strongest correlation for the mandibular first premolars (r = ±0.270). The lowest SD values, for measurements on teeth 15/25 (SD = 125,787), had the most accurate correlation with age. Thus, we can conclude that the original Kvaal method is not applicable in the age estimation of the Serbian population. For future research, we suggest using cone beam computer tomography as a precise technology to evaluate the applicability of Kvaal and other methods for age estimation.
“Love in the Later Years…”: Perceptions of Sex and Sexuality in Older Indian Adults — a Qualitative Exploration

BACKGROUND: The world faces global population ageing. With this demographic shift and increased life-expectancy, healthcare services are focused on healthy ageing. Sexual health is a vital yet neglected dimension of general health and wellbeing in older adults. This study aimed to explore sexual experiences and perceptions of sexuality among older people in India. METHODS: A qualitative approach with social constructivist paradigm was used. 20 participants aged above 60 years were recruited through purposive sampling until thematic saturation was reached. In-person, in-depth interviews were conducted using a semi-structured guide after an initial pilot study. They were audio-recorded, transcribed, and translated verbatim. Thematic analysis was conducted, and rigor ensured through triangulation and respondent validation. RESULTS: The overarching categories were sexuality as a mode of resilience, emotional stability and intimacy as attributes of sexual pleasure, and lack of sexual rights awareness. The main categories (themes) were sexual experiences (intimate touch, non-penile sex, personal meanings of sexuality), partner expectations (companionship, support, continuity of care, proximity), and barriers against sexual expression (social stereotypes, stigma, lack of audience in healthcare services). The older people were accepting of their sexual difficulties and coped through relationship dynamics. Participant voices are discussed with regard to the socio-cultural context. CONCLUSION: Sexual wellbeing is connected with ageing well. Our findings suggest that older people retain sexual desires and fantasies through changed patterns and expectations. Healthcare services, policymakers and academia need to be informed about older peoples sexual needs and rights.
Community disaster exposure and first onset of depression: A panel analysis of nationally representative South African data, 2008–2017

Sub-Saharan Africa faces unprecedented disasters, with climate change expected to exacerbate the frequency and severity of unpredictable and stressful catastrophic events. Unlike developed nations, reconstruction in developing nations is hindered by resource constraints, with certain communities potentially experiencing multiple and enduring effects of disasters. Despite the potential danger of such cumulative community disaster exposure on mental health (e.g. depression), large-scale population-level evidence for the region is limited. We investigated the association between exposure to cumulative disaster and the first onset of depression in a nationally representative survey in South Africa. We used panel data from the South African National Income Dynamics Study (SA-NIDS) from 2008–2017, consisting of 17,255 adult study participants who were depression free at baseline. Risk of first depression onset between individuals exposed and unexposed to community disaster was measured, accounting for multiple disaster exposure over time by fitting generalized estimating equation (GEE) regression models. Data on the geographic location of disasters were obtained from the South African government gazette, and mapped with the government delineated SA-NIDS households’ locations. Of the sampled individuals, 2,986 were exposed to disaster during the study duration (17.3%). Increased cumulative community disaster was significantly associated with the likelihood of depression onset (adjusted relative risk [aRR] = 1.20, p<0.01, 95% CI: 1.09–1.33), even after controlling for socio-demographic factors. In sub-group analyses, greater likelihood of depression onset was found among females [but not in men] (aRR = 1.23, p<0.01, 95% CI: 1.09–1.38), Black African [but not in other population group] (aRR = 1.21, p<0.01, 95% CI: 1.09–1.36), lower education attainment group [but not in tertiary and above educational attainment group] (aRR = 1.20, p<0.01, 95% CI: 1.08–1.33), and lower income attainment group [but not in the top income quartile group] (aRR = 1.24, p<0.01, 95% CI: 1.11–1.38), due to cumulative community disaster. Although cumulative community disaster exposure was significantly associated with the first onset of depression, its negative impact may be more pronounced among individuals considered chronically socially vulnerable (i.e. the groups above) in South Africa. Given that many individuals in South Africa rely on social, food parcel relief, and health services from government/public sector, timely access to community-based supportive intervention is needed for disaster survivors, prioritizing socially vulnerable groups to help mitigate problems associated with mental health challenges.
Online Education: An Exploratory Study among Working Adults in Logistics Industry

Online education is growing dramatically within adult learners. It enables learners to study without geographical or time constraints, providing benefits that may not be gained from classroom-based learning. This study aimed to investigate the working adults’ perceptions of online learning. 116 face-to-face interviews were conducted to collect the data. Data were analysed via SPSS. Findings confirmed that age and level of education have significant relationship with perception of E-learning. In addition, cost effective was one of the main factor which influence working adults’ intention to enrol in online education. The findings provide implications for education organisations to develop effective online education programs, attracting online learners.
Zakat and Macro Economic Effects on Indonesian Inflation

This study aims to analyze whether there is an effect of zakat, investment, exchange rate, BI rate and government spending on inflation in Indonesia for the 2009-2019 period. The type of data used is secondary data obtained from BPS, BI, Ministry of Trade through published agency reports which are analyzed using multiple linear regression with the help of the E-Views 10 Program. The results of this study are: (1) zakat variables, investment, exchange rates, The BI rate and government spending partially have no effect on inflation in Indonesia for the 2009-2019 period. (2) variables of zakat, investment, exchange rate, BI rate and government spending simultaneously have no effect on inflation in Indonesia for the 2009-2019 period. (3) The concept of inflation in the Islamic view refers to Al-Maqrizi's inflation theory which states that inflation can occur by natural conditions as well as human error and a system that is not transparent and accountable. This increase in inflation can be minimized by the concept of zakat through demand pull inflation, while investment plays a role in suppressing inflation through cost push inflation. On the other hand, macroeconomic variables such as exchange rates, BI Rate and Government Expenditures play a role in controlling inflation by applying the Islamic concept, namely the prohibition of usury, maysir and prioritizing the principle of justice.
influence of fixed orthodontic retainer on oral microbiota

Background: The oral cavity is a wide versatile microbial community in which many microbial species coexist in harmony. However, with certain circumstances, i.e. orthodontic appliances, pathogenic biofilm outgrowth occurs. The aim: The aim of this study was to compare opportunistic pathogens, associated with dental caries and periodontal disease in addition to Candida albicans, between healthy individuals and patient wearing fixed orthodontic retainers. Method: Fourty eight subjects were recruited andwere divided into retainer wearers and control cohort groups. Biofilm samples from the lingual surface of the mandibular anterior teeth of the control group and the fixed retainer surface were evaluated to detect Streptococcus mutans, Lactobacillus acidophilus, Aggrigatibacter actinomycetemcomitans, Fusobacterium nucleatum and C. albicans. Additionally, plaque (PI) and gingival (GI) indices were measured at the mandibular anterior teeth in both groups. The results: The results showed a significant increase in total micobial count in retainer group (p<0.001). The prevalence of microbial cultivity was higher in retainer group with a significant increase in PI and GI. Moreover, there was a high correlation between these genera and the GI. The conclusion: fixed retainer may increase cariogenic and periodontal pathogens and compromise oral health.