Miracle-dz/UniFAR-FTUs huggingface dataset:
Operability of Continuous Bioprocesses: Static Behavior of a Large Class of Unstructured Models

The complete static behavior of a large class of unstructured models of continuous bioprocesses is classified using elementary concepts of the singularity theory and continuation techniques. The class consists of models for which the cell growth rate is proportional to the rate of utilization of limiting substrate while the kinetics of cell growth, utilization of limiting substrate and synthesis of the desired non‐biomass product are allowed to assume general forms of substrate and product. This class of models was used extensively in the literature to model fermentation processes. Global analytical conditions are derived that allow the construction of a practical picture in the multidimensional parameter space delineating the different static behavior these models can predict, including unique steady states, coexistence of wash‐out conditions with non‐trivial steady states and multistability resulting from hysteresis. These general results are applied to a number of experimentally validated models of fermentation processes, and allow the study of the effect of kinetic and operating parameters on the stability characteristics of these models. Practical criteria are also derived for the safe operation of the bioprocesses.
Studies on Parkinson’s-Disease-Linked Genes, Brain Urea Levels and Histopathology in Rotenone Induced Parkinson’s Disease Rat Model

Parkinson’s disease (PD) is a debilitating neurological disorder that affects the aged population globally. This study aimed to explore how oral- and intraperitoneal-rotenone-induced PD alters brain urea levels, histopathology, and key Parkinsonism-related genes in the striatum. Hematoxylin and eosin staining was performed for histopathology assessment and real-time polymerase chain reaction was performed for gene expression. Rotenone 3 mg/kg body weight (Rot-3-ip) for 21 days and rotenone 50 mg/kg body weight (Rot-50-po) for 28 days significantly (p Snca, Becn1 and Prkaa1 gene expression in the striatum. Lewy bodies were visible in both Rot-3-ip and Rot-50-po rat brains. There were contrasting features in brain and liver histopathology between the oral and intraperitoneal rotenone treatment groups. However, there was no significant (p can have different impacts on the pathological sequence of events based on the molecular approach.
Correlation between body image physical activity and sleep duration with nutritional status teaching-students at the University of Darussalam Gontor for girls

Background: Malnutrition both overweight and malnutrition in children and adolescents often occur in developing countries. At this time many factors affect the nutritional status of adolescents including physical activity, psychological aspects (body image) and sleep duration. Objective: This study aims to determine the risk factors associated with the nutritional status of teaching-students at the University of Darussalam Gontor. Method: This research is an observational survey research with cross-sectional study design. Research subjects were 94 teaching-students 18-21 years old at the University of Darussalam Gontor For Girls. Statistical tests use the Gamma correlation test to determine the relationship between independent variables and dependent variables. The results of this study indicate that there was a significant correlation between body image and nutritional status (p = 0.030) and there was no significant correlation between physical activity (p = 0.385) and sleep duration (p = 0.156) with nutritional status. Keyword : Nutritional Status, Body Image, Physical Activity, Sleep Duration, Teaching Students Latar Belakang: Malnutrisi baik kelebihan berat badan dan gizi buruk pada anak-anak dan remaja sering terjadi di negara-negara berkembang. Pada saat ini banyak faktor yang mempengaruhi status gizi remaja termasuk aktivitas fisik, aspek psikologis (citra tubuh) dan durasi tidur. Tujuan: Menganalisis faktor risiko yang terkait dengan status gizi mahasiswi guru di Universitas Darussalam Gontor. Metode: Penelitian ini adalah penelitian survei observasional dengan desain studi cross-sectional , uji hipotesis statistik yang digunakan adalah Uji Korelasi Gamma. Subjek penelitian adalah 94 mahasiswi guru berusia 18-21 tahun di Universitas Darussalam Gontor Kampus Putri. Tes statistik menggunakan uji korelasi Gamma untuk menentukan hubungan antara variabel independen dan variabel dependen. Hasil penelitian ini menunjukkan bahwa ada hubungan yang signifikan antara citra tubuh dan status gizi (p = 0,030) dan tidak ada hubungan yang signifikan antara aktivitas fisik (p = 0,385) dan durasi tidur (p = 0,156) dengan status gizi. Kata kunci : status gizi, body image, aktifitas fisik, durasi tidur, mahasiswi guru.
The fracture properties of fiber metal laminates based on a 3D printed glass fiber composite

Fiber Metal Laminates (FML) are structures that contain a sequential arrangement of metal and composite materials, which are of great interest to the aerospace sector due to the superior mechanical performance. The traditional manufacturing process for FML involves considerable investment in manufacturing resources depending on the design complexity of the desired components. To mitigate such limitations, 3D printing enables direct digital manufacturing to create FML with customized configurations. In this work, a preliminary mechanical characterization of additively-manufacturing-enabled FML has been investigated. A series of continuous glass fiber-reinforced composites were printed with a Markforged system and placed between layers of aluminum alloy to manufacture hybrid laminate structures. The laminates were subjected to tensile, interfacial fracture toughness, and both low-velocity and high-velocity impact tests. The results showed that the FMLs appear to have a good degree of adhesion at the metal-composite interface, although a limited intralaminar performance was recorded. It was also observed that the low and high-velocity impact performance of the FMLs was improved by 9–13% relative to that of the constituent elements. The impact performance of the FML appeared to be related to the fiber fracture, out of plane perforation and interfacial delamination within the laminates. The present study can provide an initial research foundation for considering 3D printing in the production of hybrid laminates for static and dynamic applications.
A novel minimally invasive approach for chronic pancreatitis: combination of Frey procedure and laparoscopic distal pancreatectomy

Background: The treatment of chronic pancreatitis requires a surgical approach in patients refractory to medical therapy. During surgical treatment, ductal decompression is required, but a pancreatectomy is necessary for some patients, such as those with severe stenosis of the pancreatic duct. Importantly, inadequate procedures lead to recurrent pancreatitis. We used a novel minimally invasive approach for patients with severe stenosis of the pancreatic duct. In this report, we aim to present the feasibility and outcomes of our approach. Methods: We selected a laparoscopic approach for the distal pancreatectomy because these parts are relatively safe and the effect of reducing the length of the wound is substantial. We selected an open approach for parts of the Frey procedure because complete ductal compression has a high risk for injury to the vessels posterior to the pancreas. We examined operative outcomes, postoperative complications and recurrence of pancreatitis.Results: Our approach was performed in three patients from January 2018 to December 2018. No intraoperative complications occurred and the postoperative course was uneventful in all patients. There were no recurrence of pancreatitis and no postoperative pain in all patients in the over two years follow-up. Conclusion: Our hybrid method focusing on complete ductal compression with safety and minimal invasiveness is the optimal approach for the surgical treatment of chronic pancreatitis which requires a pancreatectomy with the Frey procedure.
Blue Phase Temperature Range at n-Cyanobiphenyl Homologue Chiral Nematic Liquid-Crystal Mixtures

Blue phase (BP) stability is dependent upon chemical structure as well as the physical properties of the chiral nematic liquid-crystal (LC) mixture. In this study, the dependence of blue phase temperature range on alkyl chain length was investigated in order to evaluate the relationship between blue phase stability and the molecular structures of four kinds of n-cyanobiphenyl (CB) homologue chiral nematic liquid-crystal mixtures composed of rod-like nematic LC. It was confirmed that blue phase temperature range was strongly dependent upon the length of the alkyl chain and the elastic constant in n-CB homologues chiral nematic LC mixtures.
Synthesis and FT‐IR Spectroscopy of Perdeuterofullerane: C60D36 Evidences of Isotope Effect in the Stability of C60D36

Perdeuterofullerane, C60D36 was synthesized in toluene solution from DCl and Zn. The FT‐IR spectrum of C60D36 was compared with that of C60H36, and the C‐H stretching and bending shift due to deuteration was measured so that Ω H/ Ω D = 1.36. The thermal stability of C60D36 was studied under N2 by thermogravimetric and differential thermal analysis. It has been found that the substitution of hydrogen with deuterium in fullerene leads to a significant increase in thermal stability which was attributed to isotope effect. In particular, the onset of decomposition of C60H36 occurred at 412°C in comparison to 465°C measured on C60D36. The maximum decomposition rate of C60H36 was found at 501°C and was shifted to 549°C in C60D36. Perdeuterofullerane was found much more stable also to air oxidation. It oxidized slowly when exposed to air and some days were needed to reach a degree of oxidation, which was reached in 1 hour by C60H36.
Utilization of prehospital emergency medical services in Saudi Arabia: An urban versus rural comparison

Background: There is limited research outside the USA, Europe, or Australia on the capacity, efficiency, and development of prehospital emergency medicine services (EMS) between urban and rural areas. This study aimed to examine the usage of prehospital EMS across rural and urban areas in Riyadh region in the Kingdom of Saudi Arabia. Methods: A random sample of 800 (400 urban and 400 rural) emergency patient records from the Saudi Red Crescent Authority EMS was collected. The following variables were analyzed: patient demographics, clinical characteristics, length of hospital stay, and length of intensive care unit (ICU) stay. Results: A skewed distribution was noted with respect to sex, i.e., 559 men versus 241 women. Rural patients were younger (42.75 vs. 39.72 years) and had significantly longer hospital (15 days versus 9 days) and ICU (5 days versus 2 days) stays than urban patients following transportation. All injury types were comparable, except for head injury, which was higher in the rural group than in the urban group. Advanced treatment and trauma transport were more often used in rural areas than in urban areas. Conclusions: In this study, rural EMS users were more likely to experience trauma-related incidents that necessitate EMS transportation, while medical reasons were more common among urban EMS users. Moreover, men used EMS at much higher rates than women and were more likely to be transported to the hospital following a call-out.
Synthesis and size-selective catalysis by supported gold nanoparticles: Study on heterogeneous and homogeneous catalytic process

Core−shell nanocomposites (R−Au) bearing well-defined gold nanoparticles as surface atoms of variable sizes (8−55 nm) have been synthesized exploiting polystyrene-based commercial anion exchangers. Immobilization of gold nanoparticles, prepared by the Frens method, onto the resin beads in the chloride form is possible by the ready exchange of the citrate-capped negatively charged gold particles. The difficulty of nanoparticle loading, avoiding aggregation, has been solved by stepwise operation. Analysis of the gold particles after immobilization and successive elution confirm the unaltered particle morphology while compared to those of the citrate-capped gold particles in colloidal dispersion. It was observed that the rate of the reaction increases with the increase in catalyst loading, which suggests the catalytic behavior of the gold nanoparticles for the reduction of the aromatic nitrocompounds. The rate constant, k, was found to be proportional to the total surface area of the nanoparticles in the sys.
Growth and Productivity of ‘Consort’ Black Currant Grown under Varying Levels of Artificial Shade

The shade tolerance of black currants (Ribes nigrum cv. Consort) was studied by measuring the growth and productivity of mature plants in the field for three seasons under full sun or artificial shade netting in Urbana, IL. Shade treatments reduced photosynthetically active radiation (PAR) from 37% to 83%. Yield was not reduced in shade levels up to 65% but decreased by as much as 66% under 83% shade. Shade had minimal effect on stem rejuvenation in the first 2 years, but reduced rejuvenation in the third year from 14 new stems in full sun to eight new stems in 83% shade. Stem diameter decreased 8% to 19% with 83% shade, whereas no changes were observed in up to 65% shade. Plant height increased 5% to 8% from open sun to 83% shade. Specific leaf weight decreased and leaf area increased with shade. Powdery mildew severity increased with shade, and disease-resistant cultivars should be considered for understory crops. Our results indicate that growth and productivity of black currants can be maintained in moderate shade but shade levels beyond 65% will significantly reduce agronomic performance.
Atmospheric dust modeling from meso to global scales with the online NMMB/BSC-Dust model – Part 1: Model description, annual simulations and evaluation

Abstract. We describe and evaluate the NMMB/BSC-Dust, a new dust aerosol cycle model embedded online within the NCEP Non-hydrostatic Multiscale Model (NMMB). NMMB is a further evolution of the operational Non-hydrostatic Mesoscale Model (WRF-NMM), which together with other upgrades has been extended from meso to global scales. Its unified non-hydrostatic dynamical core is prepared for regional and global simulation domains. The new NMMB/BSC-Dust is intended to provide short to medium-range weather and dust forecasts from regional to global scales and represents a first step towards the development of a unified chemical-weather model. This paper describes the parameterizations used in the model to simulate the dust cycle including sources, transport, deposition and interaction with radiation. We evaluate monthly and annual means of the global configuration of the model against the AEROCOM dust benchmark dataset for year 2000 including surface concentration, deposition and aerosol optical depth (AOD), and we evaluate the daily AOD variability in a regional domain at high resolution covering Northern Africa, Middle East and Europe against AERONET AOD for year 2006. The NMMB/BSC-Dust provides a good description of the horizontal distribution and temporal variability of the dust. Daily AOD correlations at the regional scale are around 0.6–0.7 on average without dust data assimilation. At the global scale the model lies within the top range of AEROCOM dust models in terms of performance statistics for surface concentration, deposition and AOD. This paper discusses the current strengths and limitations of the modeling system and points towards future improvements.
Neighbourhood deprivation, life satisfaction and earnings: Comparative analyses of neighbourhood effects at bespoke scales

Neighbourhood socioeconomic disadvantage has a profound impact on individuals’ earnings and life satisfaction. Since definitions of the neighbourhood and research designs vary greatly across studies, it is difficult to ascertain which neighbourhoods and outcomes matter the most. By conducting parallel analyses of the impact of neighbourhood deprivation on life satisfaction and earnings at multiple scales, we provide a direct empirical test of which scale matters the most and whether the effects vary between outcomes. Our identification strategy combines rich longitudinal information on individual characteristics, family background and initial job conditions for England and Wales with econometric estimators that address residential sorting bias, and we compare results for individuals living in choice-restricted social housing with results for those living in self-selected privately rented housing. We find that the effect of neighbourhood deprivation on life satisfaction and wages is negative for both outcomes and largely explained by strong residential sorting on both individual and neighbourhood characteristics rather than a genuine causal effect. We also find that the results overall do not vary by neighbourhood scale.
Generalized dispersion of unsteady convective diffusion in couple stress poorly conducting fluid bounded by porous layer in the presence of an electric field

We investigate in this paper the simultaneous effects of electric field, couple stress, porous parameter and slip at the permeable surface on the generalized dispersion of an unsteady convective diffusion in a poorly conducting fluid in a channel bounded by porous layers. A two dimensional flow has been considered and the resulting partial differential equations have been solved analytically. The solutions are computed and the results show that the solute is dispersed relative to a plane moving with the mean speed of couple stress poorly conducting fluid with a relative unsteady dispersion coefficient. These relative unsteady dispersion coefficients are numerically computed and found that they increase with the increase in porous parameter and decrease with an increase in couple stress parameters. We have also estimated the contribution of diffusion and pure convection on the generalized dispersion coefficient. The effect of pure convection, neglecting diffusion terms on mean concentration is computed and.
AI Chatbot for Tourist Recommendations: A Case Study in the City of Jeddah, Saudi Arabia

Chatbots have gained increasing importance in today research with a lot of available applications. They are flexible and can be applied in many application domains. In tourism, Chatbots can recommend sights, hotels, activities, or even full travel plans. Usually, users are required to visit plenty of websites and install different Apps into their mobile phones in order to navigate the city and planning for the trip which is inconvenient and time-consuming. To address this issue, this paper proposes “Smart Guidance”, an AI text-based chatbot that is developed as a mobile application. It simulates a chat with users in a natural language, it also provides a two-way interaction and it is a single point of contact for all user communications. We provide a use case in the city of Jeddah, Saudi Arabia. Jeddah is the second largest city in Saudi Arabia and tourists have various choices when it comes to moving around the city. The final evaluation of the chatbot showed that the bot could understand meanings and users’ requests. Moreover, users found that the interaction is effective, and the responses are provided immediately. Users were satisfied and like the idea that they could express their needs in their natural language. Furthermore, users enjoyed the interaction and felt engaged.
“The land is a healer”: Perspectives on land-based healing from Indigenous practitioners in northern Canada

This research paper articulates a largely undefined cultural concept within mental health promotion and intervention, described as ‘land-based’ healing, which has been understood and taught for millennia by Indigenous knowledge holders. This knowledge is currently being revitalized by northern practitioners where ‘land’ is understood as a relational component of healing and wellbeing. Land-based activities such as harvesting, education, ceremony, recreation, and cultural-based counselling are all components of this integrative practice. Land-based practices are centered in Indigenous pedagogy and recognize that cultural identity is interwoven with and connected to ‘land. ’ Directly cultivating this fundamental relationship, as assessed through a culturally relevant lens, increases positive mental health and wellness outcomes in Indigenous populations. In this study, qualitative narrative methods were used to document the experiences of eleven land-based program practitioners from the three northern territories in Canada. As experts in this field, practitioners’ narratives emphasized the need for a greater understanding and recognition of the value of land-based practices and programs within mainstream health. The development of working definitions, terminology, and framing of land-based practice as a common field are delineated from relevant literature and practitioner narratives in order to enable cross-cultural communication and understanding in psychology. Land-based healing is presented as a critical and culturally appropriate solution for mental health intervention and community resilience in northern Canada.
Nutritional status and other predictors of immune response recovery among HIV-AIDS patients receiving antiretroviral therapy in Dr. Sardjito Hospital, Yogyakarta, Indonesia: a retrospective cohort study

Introduction: Nutritional status and immune response of Human Immunodeficiency Virus-Acquired Immune Deficiency Syndrome (HIV-AIDS) patients are closely connected. There are limited studies assessing the influence of Body Mass Index (BMI) on immune response recovery among HIV patients in Indonesia. This study aimed to identify the BMI and other predictors of immune response recovery among HIV-AIDS patients following two years of Antiretroviral (ARV) therapy. Methods: This research was a retrospective cohort study among HIV-AIDS patients who started ARV therapy from January 2014 to December 2016 at Dr. Sardjito Hospital, Yogyakarta. Data were collected from ARV registry and medical reports. Data were analysed using linear regression. Results: A total of 255 patients were included in the study, with a median BMI of 20.07 kg/m2. Results showed that BMI was not significantly correlated with immune response recovery at the 6th, 12th, 18th, and 24th months of ARV therapy (p>0.05). But, the increase in cluster of differentiation 4 (CD4) cell count was higher in overweight and pre-obese patients than underweight patients, especially in the 18th and 24th months of therapy. Factors related to immune response recovery were the regularity of treatment at the 12th, 18th, and 24th months of ARV therapy, and the use of Tenofovir at 18th-month therapy (p<0.05). Conclusion: Immune response recovery was higher in overweight and pre-obese patients. Using Tenofovir type ARV and doing treatment regularly can increase CD4 cell counts. Underweight patients need to enhance their nutritional status to improve their immune response during ARV therapy.