Miracle-dz/UniFAR-FTUs huggingface dataset:
Effect of L-arginine and Carvedilol on Peptic Ulcer and Hypertension in Rats

Background: Adults with hypertension often suffer from peptic ulcer disease and are more likely to receive drugs for hypertension and peptic ulcer Aim of the study: The aim of this study was to evaluate effect of L-arginine and carvedilol as nitric oxide donors on peptic ulcer and on peptic ulcer hypertension comorbidity regarding to these parameters: blood pressure, ulcer score, ulcer index, total antioxidant capacity(TAC),nitric oxide (NO), prostaglandinE2(PGE2)and tumor necrosis factor alpha (TNF-α) Methods: Rats were classified into: Group 1: control normal group. Group 2carboxy methylcelluose(CMC) group. Group 3: peptic ulcer (PU)group, Group4: hypertension -PU group, Group 5: PU Larginine pretreated group, Group6: hypertension-PU L-arginine pretreated group, Group7: PU carvedilol pretreated group, Group8: hypertension -PU carvedilol pretreated group, Group9: hypertensionPU L-arginine treated group, Group 10: hypertensionPU carvedilol treated group Results: Treated groups showed significant improvement in all parameters related to PU and hypertension PU progression and improvement of the histopathology of stomach. Conclusion: Our study revealed that L-arginine and carvedilol showed improvement in blood pressure, ulcer score, ulcer index, TNF-α, TAC, NO and PGE2. There was no significant difference between both drugs. So our drugs have prophylactic effect against PU and hypertension PU co-morbidity and their effect appeared to be mediated, by reductions in oxidative stress and a preservation of gastro protective mechanisms as NO, PG E2 and TAC.
DERMATOLOGIC GELS SPREADABILITY MEASURING METHODS COMPARATIVE STUDY

Objective: The main objective of our study is the comprehensive analysis and characterization of the existing spreadability evaluation strategies, the comparison of the obtained results reproducibility and convergence through the example of the 9 most widely used dermatological gels. Methods: Dolobene®, Flucinar®, Ketorol®, Contractubex®, Dr. Theiss Venen gel®, Solcoseryl®, Deep Relief®, Hepatrombin® pharmacopoeia gel samples were analyzed using parallel-plate, “slip and drag”, and viscometry methods. Analysis was performed in flow mode at 32±0.2 °C, over shear rates ranging from 0 to 350 s−1, increasing over a period of 120 s, and was maintained at the superior limit for 10 s and then decreased during the same period. At least 5 replicates of each sample were evaluated, and the upward flow curves were fitted using the Casson mathematical model. Results: Solcoseryl® and Dolobene® showed the best spreadability in the parallel-plate method (3115.66±50.00 and 3316.63±50.00, respectively); Contractubex® and Dolobene showed the best spreadability in the “slip and drag” test (73.46±0.5 and 18.32±0.5, respectively); Solcoseryl® and Contractubex® showed the best spreadability in the viscometry test (43.86±0.5 and 76.92±0.5, respectively). Conclusion: This study analyzed the existing methods for determining the spreadability using commercially available samples of the dermatological gels as examples. The viscometric and the "Slip and drag" methods use different characteristics of spreadability, giving a complex evaluation of the measured parameter in vitro. Therefore, the combination of these two methods has the greatest prospects for reliable determination of this indicator.
Standardization or Localization – Organizational Communication on Social Media from a Cultural Perspective

A few years back, globalization and standardization were considered to be the paradigms in the area of international business. But, with changing times, it has lost its lustre considering the branding perspective in global brands. The consumers do not feel connected with highly standardized products and centralized decision-making; most global brands have even stopped any relationship with the typical standardization strategy for communication. Therefore, there is seen a rise in the influence of the localization strategies in communication. A new term is seen emerging lately, and that is 'glocalization' that encourages all the global brands to think internationally while they should act locally. Thus, this paper discusses whether global brands should localize or standardize their communication strategies using social media to be successful. The degree of cultural adaptation of web content impacts the perception of customers on the site's effectiveness. Some consumers prefer localized web content in culturally different areas, whereas some countries prefer localized web content. Keeping all these aspects in mind, organizations need to develop proper communication strategies using social media to be effective in the market and to create a strong brand image.
Gas retention and release from nuclear legacy waste

Many consolidated sediments experience in situ gas generation from methanogenesis, corrosion or radiolysis reactions, while the strength of the sediment matrix can immobilise bubbles for long periods. Particular research interest is motivated by the need to mitigate against periodic acute release of flammable hydrogen from nuclear legacy waste sludge at Sellafield, UK and Hanford, USA to ensure safe decommissioning of ageing facilities. Gas retention within nuclear legacy waste silos is mimicked at laboratory scale by decomposing hydrogen peroxide within Mg(OH)_2 sediments, using clinical x-ray computed tomography to capture the bubbles' size, shape and mobility. Tomography revealed that modest yield stresses of 7Pa were sufficient for sediments to inhibit buoyant migration of relatively large 6-9 mm diameter bubbles during 8 h of imaging, causing the bed to swell to significant voidages in the order of 30 %. Sediments up to 800Pa yield stress exhibited sufficient gas holdup to reduce the bulk sediment density to below that of an aqueous supernatant, raising the potential for acute gas release through Rayleigh-Taylor instabilities. In the absence of buoyant migration or deep drainage channels, chronic gas release from low-intermediate strength (7-1112Pa) sediments appears to be governed by diffusion along extensive networks of partially coalesced submillimetre microvoids, observed here for the first time. Lattice Boltzmann and Monte Carlo simulations reveal these networks to be highly gas-pervious, with permeabilities in the 10.1-151.6 × 10^−12 m^2 range and effective hydrogen diffusivities of 3.7-12.5 × 10^−5 m^2 s^−1. Bubbles within kiloPascal strength sediments were observed to grow by the induction of high aspect ratio lateral fractures, promoting low-tortuosity pathways for efficient gas migration and reduced holdup. Conversely, a 30Pa sediment with an additional coarse (100−800 μm) particle fraction and constricted pore throats supported large 1-8 mm bubbles of high sphericity, forming short range ganglia of < 42 bubbles which spanned < 25mm in range, thereby truncating the avenues for chronic hydrogen release.
Survey of root-knot nematodes Meloidogyne spp. associated with different economic crops and weeds in Egypt

Globally, root-knot nematodes (RKN) recorded as destructive plant pathogen with a wide host range. A field survey of RKN Meloidogyne spp. associated with different vegetable and fruit crops and weeds in sandy and clay soil was carried out in Beheira and Menoufia governorates in Egypt. A total of 81 plant and soil samples were collected and examined. Nematodes extracted from soil samples under laboratory conditions and identified then frequency of occurrence (F.O.%) and population density (P.D) were calculated. A survey in the selected locations showed remarkable frequency of occurrence and population density of RKN in many vegetable crops and weeds. Results showed that the population density and frequency of occurrence of RKN Meloidogyne spp. were greatly differed in the different crops and different locations. Results showed that frequency of occurrence of Meloidogyne spp. was 100 % in Kom Hamada, Beheira governorate, wheras the population densities recorded between 154-692 J2 / 250 g soil. Results indicated that Meloidogyne spp. recorded infecting different weeds such as:Common lambsquarters (Chenopodium murale L.), Small bindweed (Convolvulus arvensis), Common purslane (Portulaca oleracea L.) and Solanum (Solanum nigrum). The frequency of occurrence of root-knot nematodes Meloidogyne spp. showed different values in the surveyed locations.
Robust inference with censored survival data

Randomly censored survival data appear in a wide variety of applications in which the time until the occurrence of a certain event is not completely observable. In this paper, we assume that the statistician observes a possibly censored survival time along with a censoring indicator. In this setting, we study a class of M‐estimators with a bounded influence function, in the spirit of the infinitesimal approach to robustness. We outline the main asymptotic properties of the robust M‐estimators and characterize the optimal B‐robust estimator according to two possible measures of sensitivity. Building on these results, we define robust testing procedures which are natural counterparts to the classical Wald, score, and likelihood ratio tests. The empirical performance of our robust estimators and tests is assessed in two extensive simulation studies. An application to data from a well‐known medical study on head and neck cancer is also presented.
Histological Changes in the Kidneys and Heart in Experimental Acanthamoebiasis in Immunocompetent and Immunosuppressed Hosts

The course of Acanthamoeba spp. infection depends on the age and immune status of the host, and the virulence of the Acanthamoeba spp. strain. Some strains of free-living amoebae exhibit organ specificity, during the course of infection, while others may cause changes in many organs or completely lose pathogenicity. The aim of the current study was to investigate the pathological properties of Acanthamoeba spp. isolated from a patient with acute myeloid leukemia and atypical pneumonia (AM22). Moreover, the objective was to investigate the histopathological changes in the kidneys and heart of immunocompetent and immunosuppressed mice infected with Acanthamoeba spp. Amoebae were re-isolated from both the kidneys and hearts of the inoculated mice, although no cysts or trophozoites of the amoebae were detected in microscopic slides of the fragments of these organs. Acanthamoeba spp. induced changes in the kidney and heart weight of infected mice. In immunocompetent and immunosuppressed Acanthamoeba spp. infected mice, we found some histopathological changes, including areas with less acidic cytoplasm and a relaxation of muscle fibers. In further studies, it is important to analyze changes in gene and protein expressions in the heart and kidneys of hosts with disseminated acanthamoebiasis to better understand the course of infection in these organs, because the results of histological analysis varied depending on the immune status and duration of infection.
Sociodemographic and Clinical Factors of Acute Ischemic Stroke

An observational study was carried out to analyze prevalence of risk factors for ischemic stroke in hospitalized patient in a university hospital. Ninety patients were chosen by using purposive sampling technique. The mean age of patients was 59.01±9.87 years varied from 30 to 75 years and male to female ratio was 1.2:1. Highest incidence of stroke was between the 6th and 7th decade. Patients came from both rural 49 (54.4%) and urban 41 (45.6) area. Most of them belonged to the lower-middle group 70 (84.8%). Regarding education 47 (52.2%) patients had primary level education and 8 (8.9%) patients were illiterate. It was observed that among them current smoker were 30 (33.3%) and ex-smoker 17 (18.9%). It was also observed that 52 (57.8%) patients had hypertension and 32 (35.6%) had diabetes mellitus (DM). Ischemic heart disease was present in 14 (15.6%) patients. By Oxford shire classification of stroke, it was observed that PAC is common 51 (56.7%) among all forms. Majority 38 (42.2%) of patients had hospital stay of 11-15 days. The mean hospital stay was found 13.68±6.6 days. This study found that cigarette smoking, hypertension, diabetes mellitus and ischemic heart diseases are the major risk factors prevalent in our community while other risk factors demand further study. Bangladesh Journal of Neuroscience 2017; Vol. 33 (1): 18-23
Assessment of Early Outcomes of Surgical Treatment of Comminuted Fracture Calcaneus through Trans Calcaneal Approach

Background: Treatment options for displaced intra-articular calcaneal fractures are still up for debate. The gold standard treatment for intra-articular calcaneal fractures is the conventional extensile lateral approach (ELA). Objective: achievement of good reduction with stable support for intra-articular calcaneal fractures by using trans calcaneal approach aiming for better functional outcome. Methods On the basis of a prospective cohort research, at Zagazig University Hospital Orthopedic Department we recruited 18 patients with comminuted fractures in the calcaneus who had been admitted to the hospital with intra-articular fractures, Extensive lateral approach and Tplate fixation were used to treat this condition 3 and 6 months after surgery, the American Orthopedic Foot And Ankle Society's functional assessment was performed. Results: All patients eventually achieved full union by the end of follow-up. Only one patient had delayed union. Most of patients (55.56%) had good outcome according to AOFAS score. 11.11% had excellent outcome. While about one third of patients had unsatisfactory outcome, either fair (27.77%) or poor (5.56) AOFAS score. In regard to complications, most of the studied group (61.11%) didn’t have any complications, three patients had surgical site infection, and 11.11% of patients had sural neuritis. Conclusion: The trans-calcaneal method of reduction through ELA is an excellent method for treatment of displaced intra-articular calcaneal fractures, as it provides good exposure and facilitates anatomical reduction of fracture.
The Toxic Effect of some Bio Insecticides on Honey Bee Foraging Workers التأثير السمى لبعض المبيدات الحشرية الحيوية على شغالات نحل العسل

Honeybee foraging workers were exposed orally and by contact to the insecticides : chlorpyrifos, alphacypermethrin, spinosad, B.t and orange oil to evaluate the toxic effect of these insecticides under laboratory conditions. Oral toxicity tests of the tested insecticides to honeybee foragers, indicated that the LC50 of chlorpyrifos, alphacypermethrin and spinosad recorded 48.0 , 47.0, 45.0 ppm, respectively. Also it cleared that chlorpyrifos value was the height toxicity on honeybee foragers and recorded 96% mortality percentagebut on the other hand orange oil was the lower compound that recorded 25.00ppm and 50% mortality percentage on honeybee foragers at LC50 level. As for direct contact toxicity tests, the bees mortality was recorded as well as the mortality lines was illustrated, data cleared that the LC50 of chlorpyrifos, alphacypermethrin and spinosad 25.0, 20.0, 14.0 ppm, respectively. While orange oil treatment recorded the lowest LC50 as 2.0 ppm. In addition , as for the mortality percentages, chlorpyrifos recorded 50% occupied the most toxic insecticides on honeybee foragers while orange oil was the lowest recording only 4% mortality percentage. Regarding to the Initial repellence the result indicated that all tested compounds recorded high repellent during the first and second days through the treatments.
Synergies of Tradeoffs in University Life Science Research

The Bayh-Dole Act of 1980, key court decisions, and several breakthrough process technologies, paved the way for a period of remarkable growth in the patenting of life science research by U.S. universities in the 1980s and 1990s. Using a multiple-output cost framework and panel data on 96 universities over two decades this article examines whether economies of scope and/or scale are present in university production of three major life science research outputs: journal articles, patents, and doctorates. The results show strong evidence of significant economies of scope between articles and patents and economies of scale in article and patent production, suggesting that larger universities have distinct cost advantages in the production of high quality research outputs.
Book Review: Principles of CMOS VLSI Design: A Systems Perspective

An Introduction to Microprocessors: THORN EMI HOME ELECTRONICS (Macmillan, 1985,86 pp., £5.95 paperback) This text is 'a concise presentation of the functioning of a microprocessor and of the systems that can be constructed by interfacing'. The book builds upon earlier books in the Macmillan series which deal with an introduction to digital techniques and related topics. It is supported by video tapes relating to microprocessor systems. The text deals with the MOSTEK 6502 microprocessor and covers basic ideas, programming and interfacing. The treatment is intended for the enthusiast rather than the undergraduate student. Attention is directed explicitly to the chosen microprocessor and its associated chips. The novice would have considerable difficulty with this text. Without background material provided by earlier texts in the series the material would be difficult to follow. For the enthusiast wishing to know how best to exploit the 6502 the text would be useful. M. G. HARTLEY, Department of Electrical Engineering and Electronics, U MIST
What Method is to Achieve the Purposes of Systems-of-Systems Having Different Boundaries as System-of-Systems for Each Organization?

In an enterprise, designing system-of-systems (SoS) is required to assume and clarify each organization-specific viewpoint for the SoS, in order to solve problems within their budgets and benefit. The previous study suggests that designing the IT system as to achieve different purposes depending on the various positions is difficult. To solve the above problems includes two difficulties which must solve at least. One difficulty is that if the organizations do not have enough conversation among organizations, the organizations cannot reduce the range of what we do now know the ‘unknown unknowns’. Another difficulty is that to achieve two (or more) purposes at the same time. Therefore, the purpose of this study is to reduce misunderstanding at the time of SoS design in different positions that have each different purpose, in order simultaneously to achieve the purposes of SoSs which have different boundaries defining as SoS for each organization. We will propose a design method which assumes the purpose of this study, includes steps to make it that can commonize design by two positions. To evaluate the proposed method, we actually applied the proposed method to the processes for the order for sales and the maintenance for the product in the manufacturing industry.
The Effects of Previous Experience and Self Efficacy on the Acceptance of e-Learning Platforms Among Younger Students in Saudi Arabia

In Saudi Arabia, some e-learning initiatives such as the Future Gate Project (FGP) and Madrasati (MySchool) have been in place since 2018 and 2020, respectively. Amid the COVID-19 pandemic, they were used as a means of distance learning for students across the country. This paper investigates the willingness of students to use the e-learning platforms and whether it varies across different sex and age group. Primary data in the form of a survey of 265 secondary school students across the Makkah region was analysed with Structural Equation Modelling (SEM) by using the Technology Acceptance Model (TAM) as a theoretical framework. We found that students’ self-efficacy, which is strongly influenced by their previous experience with the underlying technology used in the e-learning platforms, has a positive effect for older students in high school, yet surprisingly, a negative one for younger students in middle school. We also found that perceived ease of use and social influence to be the most important factors behind the students’ acceptance of e-learning platforms and that the effects are stronger for female students than for male students. While this study was conducted in Saudi Arabia, the findings from this study provide a first-hand insight that can help ensure the continuity of the e-learning platforms if they are to be implemented permanently as distance learning platforms even after the end of the pandemic that is also applicable to any other countries.
Assessment of Nutritional status of children with special needs

1 Primary Health care Unit, Berket El-Sabae, Ministry of Health, Menoufia, Egypt. 2 Family Medicine department, Faculty of Medicine, Menoufia University, Menoufia, Egypt. Abstract: Background: Nutrition for the children with special needs is a complex concern where the altered nutritional needs, physical problems, and behavioral issues are the sequence of reciprocal causes that influence each other. Objective: This study aimed to assess the nutritional status of the children with special needs based on anthropometric measures and hemoglobin (Hb) levels. Methods: This cross-sectional study enrolled 208 children (aged from 6 to 14 years old, 92 males and 116 females) from 2 special needs children schools in Menoufia Governorate, Egypt. The included children were classified into 2 age groups (6-<11 years old) and (11-≤14 years old). Sociodemographic history, type of disability, weight of mother at delivery were obtained from the caregivers. The nutritional status of the studied children was evaluated based on anthropometric measurements according to standard WHO Z scoring procedures and Hb levels (g/dl). Results: Down syndrome represented the highest proportion of the studied participants (23.3%), followed by ADHD (16.3%). In accordance with the WHO child growth standard, 16.3% of the studied children were underweight and 46.2% were severely stunted. Regarding BMI, 24% of the participants were at risk for overweight, 11.5% were at risk for obesity, and 7.7% were severely wasted. There was a high statistically significant difference between type of disability and BMI. Moreover, a statistically significant difference was found between BMI, socioeconomic status, and mother’s weight at delivery. Besides, the mean Hb level was significantly lower in underweight females in the 11-≤14 years old age group. Conclusion. Malnutrition is a prevalent problem in children with special needs. Type of disability, socioeconomic status, and mother’s weight during pregnancy are strongly related to malnutrition in these children.
Assessment Guidelines Of Wall-Diaphragm Connections For Masonry Buildings

The connections between walls and diaphragm in masonry buildings typically consist of two major parts, which are masonry wall anchorages and timber diaphragm connections. From the NZNSEE (1995) and FEMA (2006) guidelines, the connection strength values given by both guidelines are apparently related only with the possible failures of the masonry wall anchorages, and no procedures are currently available to identify the strength values related to failure of the timber diaphragm connections. This is important to consider as the minimum strength value that will govern the wall-diaphragm connection capacity can be acquired from the timber diaphragm connections. To counter this limitation, this study recommends a set of design equations to assess the strength of the timber diaphragm connections. By using these equations, in addition to the default connection strength values provided by the current guidelines, the expected strength level of wall-diaphragm connections can be accurately assessed.