Miracle-dz/UniFAR-FTUs huggingface dataset:
Barriers to Health-Care Access: A Case Study of Bangladeshi Temporary Migrant Workers in Kuala Lumpur, Malaysia

The primary objective of this study was to identify the barriers to accessing health-care services as perceived by Bangladeshi temporary workers’ in Kuala Lumpur, Malaysia. The participants comprised 300 migrants working in the construction, manufacturing, and service sectors from three areas of Kuala Lumpur with the highest concentration of Bangladeshis. Following an analysis of the face-to-face structured interviews, the findings indicated that the main barriers were health-care providers not understanding migrant workers’ health problems, high medical costs, self-medication, and lack of transportation. It is recommended, therefore, that a pre-departure orientation program should be developed to familiarize migrant workers with the Malaysian health-care system and procedures, as well basic courses in Malay (Bahasa Melayu) and English, to help them access and use health-care services. In addition, it is suggested that a further, larger study is conducted to extend the findings to other states in Malaysia where there are Bangladeshi temporary migrant workers from similar backgrounds.
Prevalence, associated risk factors of hymenolepis nana infection among children in sohag.

Background: Hymenolepis nana is the most common cestode in human which has detrimental impact on host nutritional status. Several environmental and socio-economic factors are responsible for its continued persistence in children. Objective: To estimate the prevalence of H. nana infection in outpatients attending Sohag hospitals and correlation with some of its risk factors and Clinical manifestations. Methods: Cross-sectional study was conducted during the period from November 2018 to June 2019.A total of 500 stool samples were examined from outpatient children aged 1-15 years attending Sohag Hospitals by direct fecal smear, Lugol's iodine and formal-ether concentration technique. Risk factors and Clinical manifestations were collected using a structured questionnaire. Chi-square and logistic regression analyses were used for data analysis. Results: Results indicated that the overall prevalence of H. nana in children under study was 5.8%. Multivariate analysis indicated that age of 1-8 years(P value < 0.03; AOR = 2.9; 95% CI = 1.1-7.8), with uneducated mothers (P value < 0.04; AOR = 3.1; 95% CI = 1.1-9.1), consuming unwashed vegetables and fruits(P value < 0.01; AOR = 4.9; 95% CI =1.4-17.2), poor hand washing before eating and after toilet(P value < 0.005; AOR = 5.6; 95% CI = 1.6-19.2) as the significant risk factors of H. nana infection among these communities. The infection was significantly higher among those who had abdominal pain (P value < 0.001), anorexia (P value < 0.005) and underweight participants (BMI < 18.5kg/m2) (P value < 0.01) when compared to their asymptomatic counterparts. Conclusions: The present study highlighted on prevalence of H. nana infection in children Sohag Governorate, Egypt and provided that, H. nana infection is a public health problem and there is an urgent need for efforts towards ensuring adequate control of the infection in Sohag Governorate especially in children of school age
EFFECTS OF HIV-1 TAT PROTEIN ON STRUCTURE, FUNCTION AND TRAFFICKING OF THE DOPAMINE TRANSPORTER

HIV-1 Tat protein plays a crucial role in perturbations of the dopamine (DA) system. Our previous studies have demonstrated that Tat decreases DA uptake, and allosterically modulates DA transporter (DAT) function. In the present study, we have found that Tat interacts directly with DAT, leading to inhibition of DAT function. Through computational modeling and simulations, potential recognition binding site of human DAT (hDAT) for Tat was predicted. Mutation of tyrosine470 (Y470H) attenuated Tat-induced inhibition of DA transport, implicating the functional relevance of this residue for Tat binding to hDAT. Y470H reduced the maximal velocity of [3H]DA uptake without changes in the Km and IC50 values for DA inhibition of DA uptake but increased DA uptake potency for cocaine and GBR12909, suggesting that this residue does not overlap with the binding sites in hDAT for substrate but critical for these inhibitors. Furthermore, Y470H also led to transporter conformational transitions by affecting zinc modulation of DA uptake and WIN35,428 binding as well as enhancing basal DA efflux. 1 Midde NM, Huang X, Gomez AM, Booze RM, Zhan CG, Zhu J (2013) Mutation of tyrosine 470 of human dopamine transporter is critical for HIV-1 Tat-induced inhibition of dopamine transport and transporter conformational transitions. Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology 8:975-987. PMCID:PMC3740080 24 Collectively, these findings demonstrated Tyr470 as a functional recognition residue in hDAT for Tat-induced inhibition of DA transport and transporter conformational transitions. The consequence of mutation at this residue is to block the functional binding of Tat to hDAT without affecting physiological DA transport. 2.
The Impact of the Ventilation System on the Methane Release Hazard and Spontaneous Combustion of Coal in the Area of Exploitation—A Case Study

Various types of natural hazards are inextricably linked to the process of underground hard coal mining. Ventilation hazards—methane and spontaneous combustion of coal—are the most dangerous; they pose a major threat to the safety of the workers and decrease the effectiveness of the whole coal production process. One of the methods designed to limit the consequences of such hazards is based on the selection of a ventilation system that will be suitable for the given mining area. The article presents a case study of an active longwall area, where—due to increasing ventilation hazard (methane and spontaneous combusting of coal)—the whole system was rebuilt. The U-type ventilation system was used in the initial stage of the extraction process, however, it often generated methane in amounts that exceeded the allowable values. Consequently, such conditions forced the change of the ventilation system from a U–type to Y–type system. The new system was installed during the ongoing mining process, unlike the usual practice. The article presents the results of tests on mine gas concentrations and descriptive statistics for both types of ventilation system. The results clearly demonstrate that the U-type longwall ventilation system, in the case of high methane release hazard, prevents safe and effective operation. At the same time, the use of this system limits the carbon oxidation reactions in the goaf, leading to spontaneous heating and combustion, which is confirmed by the low concentrations of gases—by-products of these reactions. In turn, the use of the Y-type longwall ventilation system ensures safe and effective operation in areas with high methane release hazard, but at the same time deteriorates the safety associated with the spontaneous combusting of coal. The presented case—both from a scientific and practical perspective—is quite interesting and greatly broadens the knowledge in the scope of an efficient ventilation system for underground workings.
INFLUENCE OF SELF ACTUALIZATION ON JOB INVOLVEMENT AND ORGANIZATIONAL COMMITMENT AMONG ACADEMIC LEADERS WITH STRUCTURAL EQUATION MODELING

Background: In today‟s scenario, the employers are much keen about their employee‟s retention as the cost of training and orientation is higher than the recruitment cost. For that they are trying create a kind of emotional bondage with the company and the former is possible only through creating Job Satisfaction, Job Involvement and Organizational Commitment (Gopinath, 2020 a). These three factors are mutually dependent and one cannot be attained without the other, so the recent researches are much focused on these factor and they are looking for a common factor which may influence all the three factors. Self Actualization refers an individual‟s intention to attain his potential. Methods: In this paper the researcher attempt to study how this Self Actualization influences Job Involvement and Organizational Commitment and will it is really useful to enhance those things. The research was conducted with Academic Leaders and the sample size 186 was selected using Purposive Stratified Random Sampling technique. Findings: From the results structural equation modeling the researcher find significant influence of Self Actualization variables on Job Involvement and Organizational Commitment of Academic Leaders. Conclusions: As the Academic Leaders lead the employees with care, the employees not only would enhance the Job Satisfaction, but also show their Organizational Commitment.
A Data-Driven Auto-CNN-LSTM Prediction Model for Lithium-Ion Battery Remaining Useful Life

Integration of each aspect of the manufacturing process with the new generation of information technology such as the Internet of Things, big data, and cloud computing makes industrial manufacturing systems more flexible and intelligent. Industrial big data, recording all aspects of the industrial production process, contain the key value for industrial intelligence. For industrial manufacturing, an essential and widely used electronic device is the lithium-ion battery (LIB). However, accurately predicting the remaining useful life (RUL) of LIB is urgently needed to reduce unexpected maintenance and avoid accidents. Due to insufficient amount of degradation data, the prediction accuracy of data-driven methods is greatly limited. Besides, mathematical models established by model-driven methods to represent degradation process are unstable because of external factors like temperature. To solve this problem, a new LIB RUL prediction method based on improved convolution neural network (CNN) and long short-term memory (LSTM), namely Auto-CNN-LSTM, is proposed in this article. This method is developed based on deep CNN and LSTM to mine deeper information in finite data. In this method, an autoencoder is utilized to augment the dimensions of data for more effective training of CNN and LSTM. In order to obtain continuous and stable output, a filter to smooth the predicted value is used. Comparing with other commonly used methods, experiments on a real-world dataset demonstrate the effectiveness of the proposed method.
Episiotomy related morbidities measured using redness, edema, ecchymosis, discharge and apposition scale and numerical pain scale among primiparous women in Mulago National Referral Hospital, Kampala, Uganda

Introduction episiotomy induced inflammatory signs like redness, edema, ecchymosis and pain may remain beyond the period of hospitalization and can be objectively measured using redness, edema, ecchymosis, discharge and apposition (REEDA) scale. Pain in the postpartum period is a common problem and can be measured using the numerical pain scale (NPS). Episiotomy is normally poorly executed and poorly repaired with little attention to the subtle pain-free scar. Postpartum perineal pain has been found to affect more people with episiotomy compared to spontaneous perineal tears or contusion in the first two weeks. This study was aimed at comparing NPS and REEDA scores in the first two weeks of postpartum among primiparous parturients with or without episiotomy in Mulago National Referral Hospital. Methods a prospective cohort study conducted by recruiting primiparous women systematically on the first postnatal day and categorizing them into episiotomy and no episiotomy group. NPS and REEDA scale were taken at baseline and 2 weeks postpartum. Results the mean total REEDA score for primiparous women among the episiotomy group was significantly higher both on day 1 and day 14 with p-values <0.0001 and <0.0001 respectively as well as the day 14 mean NPS p-value 0.001. Conclusion episiotomy, a traumatic obstetric procedure, that heals slowly and with persistent perineal pain compare to spontaneous perineal contusion or tears.
The Role of Psychological Capital in Athletic Performance and Career Development of Adolescent Baseball Players in Taiwan

Although many baseball players dream of playing professionally, intense training together with psychological pressure and injuries may increase athletes’ burnout and may lead athletes to quit and pursue alternate careers. Therefore, it is important for athletes to manage their mental toughness on their career paths. Findings from previous psychological capital (PsyCap) studies suggested that PsyCap had a positive influence on stress reduction. Therefore, this study examined PsyCap’s effects on athletes’ performance and career development, particularly under stress. We hope the findings can provide useful suggestions for athletes and coaches. To explore the relationships of PsyCap with athletic performance and career development, a structured questionnaire was distributed to 800 baseball players enrolled in middle and high schools in Taiwan with a valid return rate of 80.9%. Confirmatory factor analysis was used to verify the relationships among PsyCap, performance, and career development. The findings showed that PsyCap had significant influence on both athletic performance and career development of the study subjects. Based on our findings, implications for baseball players and coaches as well as suggestions for future research are discussed.
Use of Agro-Industrial Wastes for the Production of a Wild Yeast Enzyme with Disintegration Activity on Plant Tissues

 Use of residues for the PGase production represented an economic and sustainable method.  The activity of PGase enhanced 37 %, with respect to the value obtained with original medium.  PGase of W. anómalus was able to disintegrate cassava tuber tissue and release the starch granules. Abstract: The objective of the present study was to develop a cost-effective medium, using agro-industrial wastes for the production of a polygalacturonase by Wickerhanomyces anomalus of interest in cassava starch industries. bioreactor. PGase of W. anomalus, was able to disintegrate cassava tuber tissue, and the starch granules contained within the cells were released into the reaction medium. Lemon peel can be used as inducer for PGase production by W. anomalus, in a low cost culture medium, appropriate for the production of the enzyme at large scale.
Interferometric scattering microscopy reveals microsecond nanoscopic protein motion on a live cell membrane

Many of the biological functions of a cell are dictated by the intricate motion of proteins within its membrane over a spatial range of nanometres to tens of micrometres and time intervals of microseconds to minutes. This rich parameter space is not accessible by fluorescence microscopy, but it is within reach of interferometric scattering (iSCAT) particle tracking. However, as iSCAT is sensitive even to single unlabelled proteins, it is often accompanied by a large speckle-like background, which poses a substantial challenge for its application to cellular imaging. Here, we employ a new image processing approach to overcome this difficulty and demonstrate tracking of transmembrane epidermal growth factor receptors with nanometre precision in all three dimensions at up to microsecond speeds and for durations of tens of minutes. We provide examples of nanoscale motion and confinement in ubiquitous processes such as diffusion in the plasma membrane, transport on filopodia and rotational motion during endocytosis. Interferometric scattering microscopy is employed to track proteins in live cell membranes, demonstrating tracking of transmembrane epidermal growth factor receptors with nanometre precision in all three dimensions at up to microsecond speeds and for durations of tens of minutes.
A Modeling Approach to Understanding Glyphosate Transport in the Belize River Watershed

OF THESIS A MODELING APPROACH TO UNDERSTANDING GLYPHOSATE TRANSPORT IN THE BELIZE RIVER WATERSHED Glyphosate is the most widely used herbicide worldwide and is often transported from application areas to surface water when solubilized in runoff or sorbed to eroded sediment. There is evidence that suggests both glyphosate and its main metabolite aminomethylphosphonic acid (AMPA) may pose a risk to human health, as well as cause adverse effects in the environment. However, consistent monitoring data is still limited, especially in developing countries. Belize is a developing nation with agriculture being a major sector of its economy and is heavily reliant on glyphosate. The widespread use of glyphosate in Belize may be resulting in glyphosate transport to drinking water resources. Samples were collected from two rural communities that rely on the Belize River for their drinking water systems, Bullet Tree and Spanish Lookout, at points upstream of the abstraction site, at the abstraction site, and at the site of drinking water distribution. Samples were analyzed using HPLC, ELISA kits, and LC-MS/MS. From these analyses, it was concluded that glyphosate was not present in any water samples at a detectable concentration. The Soil and Water Assessment Tool (SWAT) was used to develop a model of the Belize River Watershed. The model was calibrated and validated for observed flow rates using the SWAT Calibration and Uncertainty Program (SWATCUP), which revealed acceptable model performance for simulating flow. Model results indicate that glyphosate transport to the Belize River is occurring, with contributions from glyphosate sorbed to eroded sediment being significantly greater than soluble glyphosate in surface runoff (p-values <0.0). Average simulated concentrations of soluble glyphosate in both wet and dry seasons are below the European Union (EU) standard of 0.1 ppb across the watershed. However, subbasins 2, 3, and 28 were identified as higher risk areas, due to having the highest percentages of days exceeding the EU standard. Subbasin 28, located just downstream of the Spanish Lookout drinking water system, was the most significant contributor of soluble glyphosate to the river, as compared to soluble glyphosate concentrations in subbasins 2 (p-values <0.0) and 3 (p-values <0.0). Soluble glyphosate concentrations in subbasin 28 inflow and outflow exceeded the EU standard 12.53% and 11.65% of the time, respectively. This work demonstrates a framework for applying SWAT for pesticide transport modeling in developing countries, and has the potential to be a powerful and accessible tool for watershed management when monitoring data is unavailable.
Bacteria Recovered from Cultured Gilt-Head Seabream (Sparus aurata) and their Antimicrobial Susceptibilities

DOI : 10.26650/EuroJBiol.2018. 346175 Objective : Gilt-head seabream (Sparus aurata) is an important species for Turkish aquaculture and bacterial diseases are one of the limiting factors for the production of this species. The aim of this study is the identification of the bacterial disease agents in cultured gilt-head seabream in Turkey and the determination of their antibacterial susceptibilities. Materials and Methods : In this study, 27 diseased gilt-head seabream samples between 3-130 g, showing various clinical symptoms, were examined bacteriologically. Bacterial isolates recovered from moribund fish samples were identified by using standard bacteriological methods and API 20E rapid identification strips. Antibiotic susceptibility tests of 10 different substances against these isolates were determined by using Kirby-Bauer disc diffusion method. Results : Vibrio anguillarum, V. scophthalmi, V. logei, V. harveyi, Pseudomonas anguilliseptica, P. stutzeri, Staphylococcus sp. and Micrococcus luteus isolates were isolated from diseased fish samples as pure and mixed infection. It was detected that API 20E may give erroneous results for fish pathogenic bacteria since they are not included in the database of the kit. Generally, enrofloxacin, florphenicol and oxytetracycline were found to be the most effective antibiotics against bacterial isolates. Conclusion : This study is the first report for V. scophthalmi, V. logei, V. harveyi, P. stutzeri and M. luteus infections of gilt-head seabream in Turkey.
Plataformas digitales y reputación académica: análisis del área de Biblioteconomía y Documentación en España

espanolAnalisis de las preferencias de los academicos espa-noles del area de Biblioteconomia y Documentacion (ByD) en el uso de las plataformas digitales para difun-dir y promocionar su actividad investigadora desde una perspectiva de reputacion academica. La poblacion de estudio esta compuesta por los 255 academicos ads-critos a los departamentos del area de referencia de 12 universidades publicas espanolas. La metodologia se desarrolla a partir de la exploracion sistematica me-diantela busqueda manual de la poblacion en un con-junto de plataformas digitales: blog personal, pagina web personal, ORCID, Twitter, Linkedin, Google Scho-lar, ResearchGate, Academia.edu, Mendeley y el Di-rectorio Exit.Se definieron tres variables principales de analisis desde la perspectiva de la gestion de la repu-tacion academica: presencia de perfiles digitales, ges-tion de la identidad digital y visibilidad de la produccion cientifica.Los resultados revelan que ResearchGate y Google Scholar son las plataformas mas populares en-tre la comunidad estudiada y permiten intuir la ausen-cia de una estrategia o de un metodo para la gestion consciente de las plataformas digitales y de la repu-tacion academica. EnglishAnalysis of the preferences of Spanish academics in the Library and Information (LIS) area in the use of dig-ital platforms to disseminate and promote their re-search activity from an academic reputation point of view. The study population consist of the 255 academ-ics belonging to the departments of the reference area of 12 Spanish public universities.The methodology is developed from a systematic exploration by manual search of the population in a set of digital platforms: personal blog, personal website, ORCID, Twitter, Linkedin, Google Scholar, ResearchGate, Aca-demia.edu, Mendeley and the Exit Directory.Three main variables of analysis were defined from the per-spective of academic reputation building: presence of digital profiles, digital identity management and visibil-ity of scientific production.Results show that Re-searchGate and Google Scholar are the most popular platforms among the studied community and allow us to intuit the absence of a strategy or method for the conscious management of digital platforms and aca-demic reputation.
Identification of Therapeutic Targets in a Glycogen Storage Disease Type IV Mouse Model

Adult polyglucosan body disease (APBD) is a neurological, adult-onset variant of glycogen storage disease type IV caused by mutations in the glycogen branching enzyme gene. APBD is characterized by the accumulation of poorly-branched glycogen molecules which aggregate to form pathogenic inclusions, called polyglucosan bodies. Polyglucosan bodies localized to the nervous system are understood to cause the progressive neurological symptoms. We hypothesized that deficiency of the enzyme responsible for glycogen chain elongation, glycogen synthase, or of a protein involved in its activation, protein phosphatase 1 regulatory subunit 3C (PPP1R3C), could mitigate the glycogen branching enzyme deficiency and prevent polyglucosan body formation. Using the APBD mouse model, we characterized the effect of glycogen synthase and PPP1R3C deficiency on the disease phenotype and observed significant behavioural, histological and biochemical rescue. Identification of glycogen synthase and PPP1R3C as effective therapeutic targets represents a critical step towards the development of a therapy for APBD patients.