Miracle-dz/UniFAR-FTUs huggingface dataset:
Implementation of Dialectical Behavior Therapy in a Day Hospital Setting for Adolescents with Eating Disorders.

Objective This article discusses the implementation and preliminary outcomes of a Dialectical Behaviour Therapy (DBT) informed program integrated with Family Based Therapy (FBT) for adolescents with eating disorders within a day hospital program (DHP). Method A retrospective analysis of hospital records between 2013-2015 provided descriptive characteristics of patients. Weight and percentage ideal body weight at admission and discharge, frequency of binge and purge episodes at discharge and readmissions were analysed. Results Analysis of patient characteristics indicated a broad range of eating disorder and comorbid psychiatric diagnoses among patients. Preliminary outcomes revealed increased weight and percentage of ideal body weight, decreased binge-purge status and few readmissions to the program over the two-year period studied. Conclusions The implementation of a DBT informed DHP with integration of FBT is associated with improved patient outcomes. Ongoing challenges with respect to the implementation of DBT include modifying DBT to address varying developmental levels, ages and diagnoses and promoting adherence to the program by patients and families. Limitations include small sample size, uncontrolled chart review and the nature of DHP, which include a variety of components that may influence outcomes. This research will help to inform future implementation of treatment programs for adolescents with eating disorders.
Characteristics of infectious endocarditis patients from a town in Boyacá A cross-sectional study

Infectious endocarditis (IE) is a multisystemic disease caused by an infection, generally bacterial, of the endocardial surface. Its incidence is three to nine cases per 100,000 persons. Objective : to characterize the patients with a diagnosis of infectious endocarditis seen at the Hospital Universitario San Rafael de Tunja. Materials and methods : a descriptive observational study. Patients seen at the Hospital Universitario San Rafael de Tunja between January 1, 2010 and January 1, 2019. Sociodemographic, clinical, paraclinical, imaging, treatment and outcome variables were gathered. Results: a total of 87 persons with a confirmed diagnosis of infectious endocarditis were seen. The average age was 38.77 years, with an SD ± 13.32 years. Leukocytosis was seen in 90%, neutrophilia in 85%, lymphocytosis in 3%, thrombocytopenia in 4%, elevated serum CRP in 85%, transaminitis in 45%, hyponatremia in 2% and hypernatremia in 4%. All patients received antibiotic treatment; only 23% required surgery. Conclusions : this case series found similar clinical and microbiological characteristics to those reported in other national and international studies. Males were affected more often than females, with the main etiological agent being Staphylococcus aureus. Fever and infectious vasculitis signs were the main clinical manifestations, most often affecting the mitral valve. (Acta Med Colomb 2020; 45. DOI: https://doi.org/10.36104/amc.2020.1720).
Seasonal changes in sleep duration and sleep problems: A prospective study in Japanese community residents

Background A scientific understanding of the effects of seasonal changes on sleep duration and sleep problems such as insomnia and hypersomnia has yet to be elucidated; however, such an understanding could aid the establishment of an optimal sleep hygiene program to treat such problems. Methods We investigated the effects of seasonal changes on sleep duration and sleep problems in Japanese community residents. Data on 1,388 individuals aged 15–89 years who participated in the Survey of Seasonal Variations in Food Intakes conducted by the National Institute of Health and Nutrition of Japan (2004–2007) were analyzed. Participants completed a questionnaire including items on sleep duration and sleep problems (difficulty initiating sleep [DIS], difficulty maintaining sleep [DMS]/early morning awakening [EMA], and excessive daytime sleepiness [EDS]). Data were prospectively collected at four time points (spring, summer, fall, and winter). Results Seasonal changes in sleep duration were found, with the longest in winter and the shortest in summer (winter–summer difference: 0.19 h). The seasonality of sleep duration was influenced by age, sex, and residential area. In terms of age, seasonal changes in sleep duration were found in the middle and old age groups, but not in the young age group. Seasonal changes in the frequencies of sleep problems were found for some items in the young age group (DMS/EMA and EDS) and middle age group (DIS and DMS/EMA); however, no such changes were observed in the old age group. Conclusion Seasonal effects on sleep and sleep problems were found in Japanese community residents, but these varied between age groups. Furthermore, seasonal changes in sleep duration were influenced by sex and residential area.
Food taboos during pregnancy

Abstract Observing food taboos during pregnancy might have impacts on maternal and neonatal health outcomes. The author’s purpose in this review was to explore the most common food taboos during pregnancy and potential health implications. PubMed, CINAHL, and Web of Science were searched. We identified more than 50 types of tabooed food during pregnancy with examples such as fresh meat, eggs, and different varieties of fruits and vegetables. While observing food taboos may predispose women to poor nutrition outcomes, some taboos could potentially protect women against unhealthy eating habits. Our findings highlight the need to understand the dual impact of food taboos to develop effective, culturally sensitive, community-based nutrition programs.
Population Modeling Highlights Drug Disposition Differences Between Tenofovir Alafenamide and Tenofovir Disoproxil Fumarate in the Blood and Semen

Understanding antiretroviral disposition in the male genital tract, a distinct viral compartment, can provide insight for the eradication of HIV. Population pharmacokinetic modeling was conducted to investigate the disposition of tenofovir disoproxil fumarate (TDF), tenofovir alafenamide (TAF), and emtricitabine and their metabolites in blood and semen. Blood plasma and seminal plasma (SP) concentrations of tenofovir and emtricitabine were measured, as were tenofovir‐diphosphate and emtricitabine‐triphosphate concentrations in peripheral blood mononuclear cells (PBMCs) and seminal mononuclear cells. Sequential compartmental modeling described drug disposition in blood and semen. Our modeling suggests slower elimination of apparent tenofovir‐diphosphate PBMC and faster elimination of tenofovir SP after administration of TAF compared with TDF, likely reflecting flip‐flop kinetics. Additionally, TAF metabolism to tenofovir appeared slower in semen compared with blood; however, SP elimination of TAF‐derived tenofovir appeared faster than its blood plasma elimination. These findings provide valuable insight for further mechanistic study of cellular entry and drug metabolism in the male genital tract.
The teaching of numerical extensions: the case of negative numbers

Some results of a study on the teaching of negative numbers are presented. Attention is concentrated on a unified view of the teaching of numbers. This ideais based on three dimensions of the numerical knowledge: abstract, contextual and number line. The research was carried out with 127–13-year-old students and is focused on the identification of addition and subtraction, the use of the number line, additive problem solving and the possibility of following several sequences of numerical extensions. Results show the importance of previous ideas on positive numbers and how these ideas influence the knowledge of negative numbers. Also included are the resolution procedures used by the students for additive problems. Interviews with 11 students allow analysis of their different levels of understanding of the objectives of the experience.
Changes in Pomological and Physical Parameters in Rosehips during Ripening

Rosehips of various Rosa spp. are well known for having human health-promoting compounds like mineral nutrients, vitamins, fatty acids, and phenolic compounds. However, little is known about rosehip characteristics which describe the fruit quality and may indicate appropriate harvest times. Our study evaluated the pomological (width, length, and weight of fruits, flesh weight, and seed weight), texture, and CIE colour parameters (L*, a*, and b*), chroma (C), and hue angle (h°) of rosehip fruits of Rosa canina, Rosa rugosa, and genotypes of Rosa rugosa ‘Rubra’ and ‘Alba’, harvested at five ripening stages (I–V). The main results revealed that genotype and ripening stage significantly affected parameters. The significantly longest (R. canina) and widest fruits (R. Rugosa) were measured at ripening stage V. Genotypes of R. rugosa ‘Rubra’ and ‘Alba’ had significantly higher fruit and flesh weights at ripening stage V. Rosehips of all investigated genotypes expressed darkness (lower L*) during ripening, and had the highest hue angle h° values at ripening stage I while the lowest was at stage V. The significantly lowest skin elasticity of rosehips was found at stage V. However, R. canina was distinguished by the highest fruit skin elasticity and strength. As our results show, the desired pomological, colour, and texture features of various species and cultivars rosehips can be optimised according to the harvest time.
Frequent nonrandom shifts in the temporal sequence of developmental landmark events during teleost evolutionary diversification

Morphological transformations can be generated by evolutionary changes in the sequence of developmental events. In this study, we examined the evolutionary dynamics of the developmental sequence on a macroevolutionary scale in teleosts. Using the information from previous reports describing the development of 31 species, we extracted the developmental sequences of 19 landmark events involving the formation of phylogenetically conserved body parts; we then inferred ancestral developmental sequences by two different parsimony‐based methods—event‐pairing and continuous analysis. The phylogenetic comparisons of these sequences revealed event‐dependent heterogeneity in the frequency of sequence changes. Most of the sequence changes occurred as exchanges of temporally neighboring events. These heterochronic changes in developmental sequences accumulated along evolutionary time, but the precise distribution of the changes over the teleostean phylogeny remains unclear due to technical limitations.
Observed effects of wind on the intensity and spectrum of scintillation

This paper investigates the observed effect of cross-path wind on the corner frequency of the scintillation power spectrum. Propagation data from ITALSAT satellite were used in this investigation, a satellite beacon operating at 18.68 GHz, 39.59 GHz and 49.49 GHz and covering two months, June and July 1997. The data were obtained at Sparsholt (51.5850° N, 1.5033°W), UK, at an elevation angle thetas=29.9° and at a sampling rate of 1 Hz, using a Cassegrain antenna of diameter 1.22 m for the 18.68 GHz and 0.61 m for the 39.59 GHz and 49.49 GHz. The results show some correlation between the corner frequency and transverse wind speed, a weaker correlation with over-all wind speed and a poor correlation between scintillation intensity and wind speed.
Microwave Radiometric Observations Near 19.35, 92 and 183 GHz of Precipitation in Tropical Storm Cora

Abstract Observations of rain cells in the remains of a decaying tropical storm were made by Airborne Microwave Radiometers at 19.35 and 92 GHz and three frequencies near 183 GHz. Extremely low brightness temperatures, as low as 140 K, were noted in the 92 and 183 GHz observations. These can be accounted for by the ice often associated with raindrop formation. Further, the 183 GHz observations can be interpreted in terms of the height of the ice. The brightness temperatures observed suggest the presence of precipitationsized ice as high as 9 km or more.
Mshelia, James Buba and Anchor, J.R Political risk assessment by multinational corporations in African markets: A Nigerian perspective Original Citation Mshelia,

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Unconditional Basis and Gordon–Lewis Constants for Spaces of Polynomials

Abstract No infinite dimensional Banach space X is known which has the property that for m ⩾2 the Banach space of all continuous m -homogeneous polynomials on X has an unconditional basis. Following a program originally initiated by Gordon and Lewis we study unconditionality in spaces of m -homogeneous polynomials and symmetric tensor products of order m in Banach spaces. We show that for each Banach space X which has a dual with an unconditional basis ( x * i ), the approximable (nuclear) m -homogeneous polynomials on X have an unconditional basis if and only if the monomial basis with respect to ( x * i ) is unconditional. Moreover, we determine an asymptotically correct estimate for the unconditional basis constant of all m -homogeneous polynomials on l n p and use this result to narrow down considerably the list of natural candidates X with the above property.
Prediagnostic blood levels of organochlorines and risk of non‐Hodgkin lymphoma in three prospective cohorts in China and Singapore

Specific organochlorines (OCs) have been associated with non‐Hodgkin lymphoma (NHL) with varying degrees of evidence. These associations have not been evaluated in Asia, where the high exposure and historical environmental contamination of certain OC pesticides (e.g., dichlorodiphenyltrichloroethane [DDT], hexachlorocyclohexane [HCH]) are different from Western populations. We evaluated NHL risk and prediagnostic blood levels of OC pesticides/metabolites and polychlorinated biphenyl congeners in a case–control study of 167 NHL cases and 167 controls nested within three prospective cohorts in Shanghai and Singapore. Conditional logistic regression was used to analyze lipid‐adjusted OC levels and NHL risk. Median levels of p,p′‐dichlorodiphenyldichloroethylene (p,p′‐DDE), the primary DDT metabolite, and β‐HCH were up to 12 and 65 times higher, respectively, in samples from the Asian cohorts compared to several cohorts in the United States and Norway. An increased risk of NHL was observed among those with higher β‐HCH levels both overall (3rd vs. 1st tertile OR = 1.8, 95%CI = 1.0–3.2; ptrend = 0.049) and after excluding cases diagnosed within 2 years of blood collection (3rd vs. 1st tertile OR = 2.0, 95%CI = 1.1–3.9; ptrend = 0.03), and the association was highly consistent across the three cohorts. No significant associations were observed for other OCs, including p,p′‐DDE. Our findings provide support for an association between β‐HCH blood levels and NHL risk. This is a concern because substantial quantities of persistent, toxic residues of HCH are present in the environment worldwide. Although there is some evidence that DDT is associated with NHL, our findings for p,p′‐DDE do not support an association.
The plane-wave time-domain algorithm for the fast analysis of transient wave phenomena

This article describes a plane-wave time-domain (PWTD) algorithm that facilitates the fast evaluation of transient wave fields produced by surface scattering. The algorithm presented relies on a Whittaker-type expansion of transient fields in terms of propagating plane waves. The incorporation of the PWTD scheme into existing matching-on-in-time- (MOT-) based integral-equation solvers is elucidated. It is shown that the computational cost of performing a surface-scattering analysis, using two-level and multilevel PWTD-enhanced MOT schemes, scales as O(N/sub t/N/sub s//sup 1.5/ log N/sub s/) and O(N/sub t/N/sub s/log/sup 2/N/sub s/), respectively, when the surface source density is represented by N/sub s/ spatial and N/sub t/ temporal samples. Hence, the computational cost of the proposed algorithms scales much more favorably than that of classical MOT schemes, which scale as O(N/sub t/N/sub s//sup 2/). Therefore, PWTD-enhanced MOT schemes make possible the analysis of broadband scattering from structures of unprecedented dimensions.
Crystal statistics. I. A two-dimensional model with an order-disorder transition

The partition function of a two-dimensional "ferromagnetic" with scalar "spins" (Ising model) is computed rigorously for the case of vanishing field. The eigenwert problem involved in the corresponding computation for a long strip crystal of finite width ($n$ atoms), joined straight to itself around a cylinder, is solved by direct product decomposition; in the special case $n=\ensuremath{\infty}$ an integral replaces a sum. The choice of different interaction energies ($\ifmmode\pm\else\textpm\fi{}J,\ifmmode\pm\else\textpm\fi{}{J}^{\ensuremath{'}}$) in the (0 1) and (1 0) directions does not complicate the problem. The two-way infinite crystal has an order-disorder transition at a temperature $T={T}_{c}$ given by the condition $sinh(\frac{2J}{k{T}_{c}}) sinh(\frac{2{J}^{\ensuremath{'}}}{k{T}_{c}})=1. $ The energy is a continuous function of $T$; but the specific heat becomes infinite as $\ensuremath{-}log |T\ensuremath{-}{T}_{c}|$. For strips of finite width, the maximum of the specific heat increases linearly with $log n$. The order-converting dual transformation invented by Kramers and Wannier effects a simple automorphism of the basis of the quaternion algebra which is natural to the problem in hand. In addition to the thermodynamic properties of the massive crystal, the free energy of a (0 1) boundary between areas of opposite order is computed; on this basis the mean ordered length of a strip crystal is ${(\mathrm{exp} (\frac{2J}{\mathrm{kT}}) tanh(\frac{2{J}^{\ensuremath{'}}}{\mathrm{kT}}))}^{n}. $
Rapidly oscillating M giant stars

ABSTRA C T The Hipparcos mission discovered a few dozen M giant stars with periods P shorter than 10 d. Similar stars may be found in other large data bases of new variables (e.g., OGLE). The three possible sources of the magnitude variations ‐ pulsation, starspots and ellipsoidal deformation ‐ are discussed in general terms. The parallaxes and V 2 I colour indices are used to calculate radii and temperatures for all M giant variables with P , 100 d. Masses are estimated from the positions of the stars in a Hertzsprung‐Russell (HR) diagram, using evolutionary tracks. Using these data, it is shown that starspots can be ruled out as a variability mechanism in almost all cases, and ellipsoidal variations in about half of the stars. Pulsation in very high-overtone modes appears to be the only viable explanation for the stars with P , 10 d. Many of the stars may be multiperiodic. IRAS data are used to deduce information about reddening and circumstellar dust. The apparently low level of mass-loss, as well as the kinematics and the spatial distribution of the stars, indicates that they are from a relatively young (i.e., thin disc) giant star population.
Atopic eczema: burden of disease and individual suffering – results from a large EU study in adults

Atopic eczema (AE, atopic dermatitis) is one of the most common non‐communicable inflammatory skin diseases affecting 1–5% of the adult population in Europe with marked impairment in quality of life. In spite of great progress in understanding the pathophysiology of disturbed skin barrier and immune deviation, AE still represents a problem in daily clinical practice. Furthermore, the true impact of AE on individual suffering is often not recognized.
Mining the Protein Data Bank to inspire fragment library design

The fragment approach has emerged as a method of choice for drug design, as it allows difficult therapeutic targets to be addressed. Success lies in the choice of the screened chemical library and the biophysical screening method, and also in the quality of the selected fragment and structural information used to develop a drug-like ligand. It has recently been proposed that promiscuous compounds, i.e., those that bind to several proteins, present an advantage for the fragment approach because they are likely to give frequent hits in screening. In this study, we searched the Protein Data Bank for fragments with multiple binding modes and targeting different sites. We identified 203 fragments represented by 90 scaffolds, some of which are not or hardly present in commercial fragment libraries. By contrast to other available fragment libraries, the studied set is enriched in fragments with a marked three-dimensional character (download at 10.5281/zenodo.7554649).
Learning‐based multi‐constraint resilient controller placement and assignment in software‐defined networks using covering graph

The controller placement problem is one of the most important issues in designing software‐defined networks (SDNs). In this context, one of the major challenges is the problem of multi‐constraint resilient controller placement and assignment (MCRCPA). In this article, considering the main criteria for solving the problem of MCRCPA, we propose a learning‐based approach named Lb‐MCRCPA, which includes a wide range of constraints including resiliency, switch‐to‐controller delay, switch‐to‐controller reliability, inter‐controller delay, and controller capacity in both main and backup modes. In the proposed method, we use an innovative structure called constraint covering graph (CCG) to calculate the reliability and to apply the set of constraints. The CCG is converted into a distributed learning model called irregular cellular learning automata (ICLA). The rules embedded in ICLA, together with the proposed assignment algorithm, can accurately determine the location of controllers. The performance evaluation of the proposed method for about 2600 different cases on more than 20 standard topologies of different sizes, not only proves its superiority over other methods but also proves its near‐optimality compared to the optimal solution.