Miracle-dz/UniFAR-FTUs huggingface dataset:
Solar and lunar tidal variabilities in GPS‐TEC and geomagnetic field variations: Seasonal as well as during the sudden stratospheric warming of 2010

The Global Positioning System (GPS) deduced total electron content (TEC) data at 15°N (geomagnetic), which is the northern crest region of equatorial ionization anomaly, are used to study solar and lunar tidal variabilities during the years 2008 and 2009 and also during the 2009–2010 winter, when a major sudden stratospheric warming (SSW) event has occurred. The diurnal and semidiurnal tidal amplitudes show semiannual variation with maximum amplitudes during February–March and September–November, whereas terdiurnal tide is larger during April–September. They show significant longitudinal variability with larger (smaller) amplitudes over 250°E–150°E (200°E–250°E). Lunar semidiurnal tidal amplitudes show sporadic enhancements during northern winter months and negligible amplitudes during northern summer months. They also show notable longitudinal variabilities. The solar migrating tides DW1 and SW2 show semiannual variation with larger amplitudes during spring equinox months, whereas TW3 maximizes during northern summer. DW2 shows larger amplitudes during summer months. During the SSW, except TW3, the migrating tides DW1 and SW2 show considerable enhancements. Among solar nonmigrating tides, SW1, TW2, and DS0 show larger enhancements. Solar tides in TEC and equatorial electrojet strength over Tirunelveli vary with the time scale of 60 days during October 2009–March 2010 similar to ozone mass mixing ratio at 10 hPa, and this confirms the vital role of ozone in tidal variabilities in ionospheric parameters. Lunar tidal amplitudes in changes in horizontal component of geomagnetic field (ΔH) are larger over Tirunelveli, a station near dip equator. Solar semidiurnal tides in ΔH have larger amplitudes than lunar tides over polar stations, Mawson and Godhavn.
Origin and distribution of mud diapirs in the Yinggehai basin and their relation to the migration and accumulation of natural gas

Mud diapirs are characteristic anomalous seismic-geologic bodies in the Yinggehai basin on the northern margin of the South China Sea and have the less compact,abnormally high-pressure and -temperature and low-density and -velocity geophysical characteristics.They show pronounced zoning and are distributed en echelon in a nearly N-S direction along the northwest trend of the basin.The origin and distribution of the mud diapirs were controlled mainly by the combined action of the great abnormally high-temperature and -pressure potential energy produced by rapid subsidence of the basin and inequilibrium between the filling-compaction of rapidly deposited sediments and fluids squeezed out and the dextral strike-slip extension of regional basin-controlling faults in the late stage.The natural gas and CO_2 migration and accumulation were effectively controlled by the effective combination of the upward intrusion of the late-stage mud-diapir thermal fluids and their accumulation conditions.
EPIDEMIOLOGY OF EIMERIOSIS IN BROILER AND LAYER FLOCKS IN AND AROUND LAHORE, PAKISTAN

The study was designed to record coccidiosis disease in broiler and layer flock in and around the Lahore District of Pakistan during the one year period out of 119 broiler flocks affected with different disease problem 51 broiler flocks were affected with this disease. The prevalence of disease was found to be 42.85 % in broiler flocks. The result revealed that out of 127 layer flocks 42 layer flocks were affected with coccidiosis. The prevalence of the disease in layer was 33.07% while in broiler it was highest (51.7%) during late summer followed by winter (45.9%) then summer (37.5%) whereas the lowest (34.48%) during spring season. The highest prevalence (65.78%) was noted in 3-4 weeks birds and the lowest (6.66%) during their earlier age (1-2 weeks). Prevalence of coccidiosis in layer was the highest during late summer (45.00%) followed by winter (35.50%), summer 25.71%) whereas the lowest (20%) was found during spring season. The highest (54.16%) prevalence was recorded in layers of 5-6 weeks and the lowest (7.14%) during their earlier age (1-2) weeks.
Marine redox variations during the Ediacaran–Cambrian transition on the Yangtze Platform, South China

The widely developed black shales on the Yangtze Platform recorded palaeoceanographic environment information during the Ediacaran–Cambrian transition. This paper describes an integrated geochemical study of rare earth elements (REEs), redox‐sensitive trace elements (RSTEs), and total organic carbon (TOC) contents in Ediacaran–Cambrian black shales at Daotuo, northeastern Guizhou Province, South China. Integrated RSTE data from the Daotuo area, in combination with previously published Fe speciation and Mo‐based proxies from another six sections (Shatan, Jiulongwan, Zhongling, Yangjiaping, Longbizui and Wuhe), suggest three major periods of water euxinia during the Ediacaran–Cambrian transition. Under these conditions, organic matter and RSTEs experienced various levels of enrichment in the black shales, especially in the lower Jiumenchong Formation. Given the patterns of Mo‐U covariations, metal‐oxyhydroxide particulate shuttles may have operated during the black shale deposition of the Doushantuo Formation (Member II) at Daotuo. Conspicuously, the upper slope water was oxic‐dysoxic during the earliest Cambrian, as determined by the REE, RSTE data and sedimentological characteristics of the Liuchapo Formation and the basal Jiumenchong Formation. The generally low RSTE concentrations in the Bianmachong Formation black shales (Cambrian Series 2, end of Stage 3) suggest a persistently oxic water column in upper slope settings. The coincidence between the marine oxygenation and the development of the ecosystem likely indicates the galvanizing effects of enhanced oxygen and biological element content on the fauna during the Ediacaran–Cambrian transition. Copyright © 2016 John Wiley & Sons, Ltd.
A Global Analysis of Extreme Events and Consequences for the Terrestrial Carbon Cycle

Latest climate projections suggest that both frequency and intensity of climate extremes will be substantially modified over the course of the coming decades. As a consequence, we need to understand to what extent and via which pathways climate extremes affect the state and functionality of terrestrial ecosystems and the associated biogeochemical cycles on a global scale. So far the impacts of climate extremes on the terrestrial biosphere were mainly investigated on the basis of case studies, while global assessments are widely lacking. In order to facilitate global analysis of this kind, we present a methodological framework that firstly detects spatiotemporally contiguous extremes in Earth observations, and secondly infers the likely pathway of the preceding climate anomaly. The approach does not require long time series, is computationally fast, and easily applicable to a variety of datasets with different spatial and temporal resolutions. The key element of our analysis strategy is to directly search in the relevant observations for spatiotemporally connected components exceeding a certain percentile threshold. We also put an emphasis on characterization of extreme event distribution, and scrutinize the attribution issue. We exemplify the analysis strategy by exploring the fraction of absorbed photosynthetically active radiation (fAPAR) from 1982-2011. Our 1This chapter is published as Zscheischler, J., M. D. Mahecha, S. Harmeling, and M. Reichstein, 2013. Ecological Informatics 4, 743–758. 26 Detection and attribution of large extreme events results suggest that the hot spots of extremes in fAPAR lie in Northeastern Brazil, Southeastern Australia, Kenya and Tanzania. Moreover, we demonstrate that the size distribution of extremes follow a distinct power law. The attribution framework reveals that extremes in fAPAR are primarily driven by phases of water scarcity.
Identification of Optimum Plant Population and Nitrogen Dose in Maize for Mid Hills Conditions of Nepal

An experiment was conducted in the summer seasons of 2021 and 2022 at the National Agronomy Research Centre's Farm Khumaltar to find out the appropriate row spacing and optimum nitrogen dose for maize. The experiment was laid out in a split plot design where nitrogen levels were allocated in the main plot and row spacing was assigned in subplots. The four different nitrogen levels were 120:60:40 N:P2O5:K2O kg ha-1, 150:60:40 N:P2O5:K2O kg ha-1, 180:60:40 N:P2O5:K2O kg ha-1 and 210:60:40 N: P2O5:K2O kg ha-1. Four different rows spacing were 75 cm, 60 cm, 50 cm and 43 cm. Seeds were sown at 25 cm apart. The individual plot size was 4m x 3m. Maize variety BGBY POP was used in the experiment. The sowing dates were 6 May and 19 May in 2021 and 2022 respectively. In the combined analysis of two-year data, days to 50% tasseling was found significant in 150:60:40 N: P2O5:K2O kg ha-1 while other traits were found non-significant. The mean grain yield was 4.29 t ha-1. Few traits were found significant in subplot factor i.e., cob diameter (4.38 cm), cob length (16.72 cm), ear height (107.1 cm) and seed per row (28.84) were found superior to other treatments within traits while all other traits in subplot factor were non-significant in pool analysis. Late maize sowing in the second year and rainfall during earthing up affected maize performance and gave lower maize yield. From the experiment, we could say that sowing of maize should be done within the second week of May and more experiments need to be done to conclude nitrogen optimization.
MiR-145 Alleviates Sepsis-Induced Inflammatory Responses and Organ Injury by Targeting ADAM17.

BACKGROUND Current studies have demonstrated that disintegrin and metalloproteinase 17 (ADAM17) plays a critical role in the pathogenesis of sepsis. MicroRNA (miR)-145 is known to control immune responses as an anti-inflammatory modulatory molecule. However, a fundamental understanding of how miR-145 regulates ADAM17 and, more broadly, sepsis-induced inflammatory response remains unknown. METHODS We used western blotting and quantitative real-time PCR (qRT-PCR) to measure expression levels of ADAM17 and miR-145. Enzyme-linked immunosorbent assays (ELISA) were performed to measure cytokine production. To determine if ADAM17 is a target gene of miR-145, bioinformatics analyses and luciferase reporter assays were conducted. The impacts of ADAM17 and miR-145 on sepsis-induced inflammatory responses were accessed in vitro using human umbilical endothelial cells (HUVECs) treated with lipopolysaccharide (LPS). Sepsis-induced inflammatory response was measured in vivo using a polymicrobial septic mouse model induced by cecal ligation and puncture (CLP) with pre-injection of a miR-145 agomir. RESULTS In HUVECs treated with LPS, miR-145 expression was downregulated and miR-145 negatively regulated ADAM17 expression through direct binding to the ADAM17 transcript 3'-UTR. MiR-145 overexpression markedly reduced LPS-induced inflammatory cytokine production by targeting ADAM17 in HUVECs. In comparison to CLP-induced septic mice treated with a control agomir, treatment with a miR-145 agomir significantly reduced the expression of ADAM17, numerous downstream cytokines such as IL-6, TNF-α, IL-1β and MCP-1, and the endothelial injury factors ICAM-1, VCAM-1. The miR-145 agomir also alleviated acute lung and kidney injury and improved the survival rate of septic mice. CONCLUSIONS This study showed that miR-145, by specifically targeting ADAM17, negatively regulates sepsis-induced inflammatory responses and vascular endothelial injury, and ultimately improved organ injury and survival during sepsis. The underlying mechanism for the regulation of ADAM17 expression by miR-145 and sepsis-induced inflammatory reactions may offer sepsis patients a novel therapeutic option.
The Occurrence of a Plastic Pen Inside the Gut of a Yellowfin Tuna Thunnus albacares (Bonnaterre, 1788)

The present paper reports the occurrence of a plastic pen inside the gut of a yellowfin tuna, Thunnus albacares (Bonnaterre, 1788) collected from Junglighat fish landing centre, Port Blair, India on 23 October 2017. The pen measuring 13.7 cm long was found in the stomach of the fish . The total length and weight of the fish was 43 cm and 4.6 kg respectively and gut/stomach length was 18.8 cm.
Evaluation of the Efficacy of Effective Microorganisms in the Reclamation of Degraded Soils

The article assesses the suitability of effective microorganisms (EM) for the reclamation of degraded soils. The aim of the research was to determine the reclamation effectiveness of the use of EM against the background of min - eral wool used together with sewage sludge or mineral fertilization with nitrogen, phosphorus, potassium (NPK) on soils degraded as a result of sulfur extraction. The effectiveness of reclamation was assessed on the basis of changes in the total organic carbon (TOC) content and the properties of humic compounds. The obtained results showed that the use of effective microorganisms in relation to mineral wool and wool used in combination with sewage sludge or NPK causes significant changes in the content and quality of soil organic matter. The observed decrease in the content of TOC, humins and an increase in the share of carbon of labile fractions and free and loosely bound with silicate-free (R 2 O 3 ) and calcium (Ca) humus forms indicate, that in the soils in which effective microorganisms were used, mineralization processes dominated in the transformation of soil organic matter. The humification process resulted in more durable humic compounds with a higher content of humic acids and humic acids to fulvic acids ratio (C-HA:C-FA). Supplementing commonly used materials in soil reclamation with the introduction of effective microorganisms is a promising technology. Further research is necessary to determine the composition of these biofertilisers and the optimal doses at which they should be used.
Evaluation of Clinical Preventive Management Provided by Primary Healthcare Physicians Against Brucellosis in Saudi Arabia

Background: Brucellosis is among the most common zoonotic bacterial infections, leading to major public health consequences in endemic areas such as Saudi Arabia. Primary healthcare is crucial in controlling brucellosis, as it serves as the frontline for disease prevention, early detection, and appropriate management. However, enhancing the contribution of primary healthcare to the entire brucellosis notification process is necessary to minimize the underreporting and inadequate data collection, which hinders the implementation of effective control measures. Objective: The objective of the study is to assess primary care physicians' knowledge and practice of clinical preventive management in Saudi Arabia regarding brucellosis using an adapted assessment tool featuring a semi-structured questionnaire. Subjects and methods: The current study's design is a cross-sectional study based on a questionnaire. Three hundred and seventy-three primary healthcare physicians in Saudi Arabia were chosen for self-administered online standardized questionnaires. Results: One-third of the participants answered all the knowledge assessment questions correctly. Most participants had more than 10 years of professional experience and were 40 or older. In response to the practice assessment questions, 210 physicians stated that they had encountered at least one case of brucellosis, and two-thirds had no compliance with the notification process of their cases. Conclusion: The limited knowledge and improper practice of primary care physicians regarding human brucellosis are possible underlying reasons for the underdiagnosis and underreporting of brucellosis patients at primary health care clinics in Saudi Arabia. Most research indicates that implementing specific educational programs to improve knowledge is necessary for primary healthcare workers. Furthermore, enhancing the community interaction between healthcare centers and the community facilitates effective control measures against brucellosis.
English teachers’ beliefs and practices in integrating digital literacy in the language classroom

This case study investigates teachers’ beliefs (i.e., behavioral, normative, and control beliefs) and practices in integrating digital literacy in English as foreign language (EFL) classroom. A descriptive study on EFL teachers is used in this research. Four participants were purposively selected to give sufficient information to answer the research questions. Data from the participants were collected by using interviews, observation, and documentation. In terms of the teachers’ beliefs, the finding shows that the behavioral belief was related to the benefits of using digital literacy; normative belief dealt with the expectation in the social context of both superiors and peers; while control belief was about the availability of particular digital technology to be implemented in the classroom and the ability of teachers. With regard to the teachers’ practices, it was found that the teachers used several digital tools for searching for information, communication, collaboration, creativity, critical thinking, cultural understanding, and e-safety. It was evident that teachers’ strong beliefs in integrating digital literacy influence the implementation of digital literacy in the classroom. The findings of this study highlight the importance of cultivating teachers’ beliefs toward the actual implementation of the integration of digital literacy in the EFL classroom.
Stream Temperature Impacts Because of Changes in Air Temperature, Land Cover and Stream Discharge: Navarro River Watershed, California, USA

Stream temperatures are critically important to aquatic ecology, especially cold‐water fish such as salmonids. Stream temperatures are influenced by multiple factors, including local climate, solar radiation on the stream channel, stream discharge volume and groundwater contributions. The Heat Source hydrodynamic and thermodynamic numerical model was used to evaluate temperatures in three stream reaches in the Navarro River watershed, California, USA. The model was calibrated and validated for summer 2015 conditions and then applied to scenarios that address changes in air temperatures, riparian forest cover and stream discharge. Modelling results indicate that stream temperatures are sensitive to changes in air temperatures and riparian forest cover and that higher discharge volume mitigates those impacts. Modelled stream maximum weekly average temperatures (MWAT) increased by 1.5–2.3°C in response to an air temperature increases of 3.5°C under low flow conditions (drought) but by only 0.9–2.0°C under moderate flow. Complete removal of riparian forest in a large‐scale forest fire would increase MWAT by 2.2–5.9°C in low discharges and by 1.0–4.4°C under moderate discharge. Riparian zone reforestation would decrease MWATs by less than 0.8°C, a modest change reflecting high existing shade on the modelled stream reaches. Comparison of identical climate and land cover change scenarios under low and moderate discharge conditions reveals that efforts to conserve stream discharge volume could be an effective mechanism to mitigate stream temperature increases. Copyright © 2016 John Wiley & Sons, Ltd.
The Trimeric Autotransporter Adhesin EmaA and Infective Endocarditis

Infective endocarditis (IE), a disease of the endocardial surface of the heart, is usually of bacterial origin and disproportionally affects individuals with underlying structural heart disease. Although IE is typically associated with Gram-positive bacteria, a minority of cases are caused by a group of Gram-negative species referred to as the HACEK group. These species, classically associated with the oral cavity, consist of bacteria from the genera Haemophilus (excluding Haemophilus influenzae), Aggregatibacter, Cardiobacterium, Eikenella, and Kingella. Aggregatibacter actinomycetemcomitans, a bacterium of the Pasteurellaceae family, is classically associated with Aggressive Periodontitis and is also concomitant with the chronic form of the disease. Bacterial colonization of the oral cavity serves as a reservoir for infection at distal body sites via hematological spreading. A. actinomycetemcomitans adheres to and causes disease at multiple physiologic niches using a diverse array of bacterial cell surface structures, which include both fimbrial and nonfimbrial adhesins. The nonfimbrial adhesin EmaA (extracellular matrix binding protein adhesin A), which displays sequence heterogeneity dependent on the serotype of the bacterium, has been identified as a virulence determinant in the initiation of IE. In this chapter, we will discuss the known biochemical, molecular, and structural aspects of this protein, including its interactions with extracellular matrix components and how this multifunctional adhesin may contribute to the pathogenicity of A. actinomycetemcomitans.
Baerveldt glaucoma implant with Supramid© ripcord stent in neovascular glaucoma: a case series.

AIM To report the outcome of Baerveldt glaucoma implant (BGI) with Supramid© ripcord use in neovascular glaucoma (NVG). METHODS We retrospectively evaluated the surgical outcome of the BGI with Supramid© 3/0 ripcord stent in patients with NVG. No tube ligation or venting slits were performed. Supramid was removed after 3mo if the target intraocular pressure (IOP) was not achieved. Surgical success was defined as IOP≤21 mm Hg with (qualified success) or without IOP-lowering medications (complete success). RESULTS Twenty-six eyes from 24 patients were included in the study. The median duration of follow-up was 4 [interquartile range (IQR)=1-5]y, ranging from 0.5 to 5y. IOP decreased by a mean of 24.2 mm Hg (59.7%); from a mean of 40.5±12.6 mm Hg at baseline to 16.3±11.9 mm Hg, P≤0.001. The number of glaucoma medications reduced from a median of 5 (IQR=5-6) to 1 (IQR=0-2, P≤0.001) at the final follow-up. Overall success rates were 88.0% at 1y, 34.8% at 3y, 66.7% at 4y, and 50% at 5y. Hypertensive phase (HP) in the first 3mo occurred in 15/26 eyes (57.7%) with a mean IOP of 31.1 mm Hg. CONCLUSION BGI with Supramid© ripcord stent gives close to 90% of the overall survival rate at the final follow-up without significant early hypotony. However, early HP is still a challenge.
Lethal Mutagenesis of Rift Valley Fever Virus Induced by Favipiravir

Rift Valley fever virus (RVFV) is an emerging, mosquito-borne, zoonotic pathogen with recurrent outbreaks taking a considerable toll in human deaths in many African countries, for which no effective treatment is available. In cell culture studies and with laboratory animal models, the nucleoside analogue favipiravir (T-705) has demonstrated great potential for the treatment of several seasonal, chronic, and emerging RNA virus infections in humans, suggesting applicability to control some viral outbreaks. ABSTRACT Rift Valley fever virus (RVFV) is an emerging, mosquito-borne, zoonotic pathogen with recurrent outbreaks taking a considerable toll in human deaths in many African countries, for which no effective treatment is available. In cell culture studies and with laboratory animal models, the nucleoside analogue favipiravir (T-705) has demonstrated great potential for the treatment of several seasonal, chronic, and emerging RNA virus infections in humans, suggesting applicability to control some viral outbreaks. Treatment with favipiravir was shown to reduce the infectivity of Rift Valley fever virus both in cell cultures and in experimental animal models, but the mechanism of this protective effect is not understood. In this work, we show that favipiravir at concentrations well below the toxicity threshold estimated for cells is able to extinguish RVFV from infected cell cultures. Nucleotide sequence analysis has documented RVFV mutagenesis associated with virus extinction, with a significant increase in G to A and C to U transition frequencies and a decrease of specific infectivity, hallmarks of lethal mutagenesis.