Miracle-dz/UniFAR-FTUs huggingface dataset:
Less is more in Corona Virus Disease 2019

both the World Health Organization guidance for the clinical management of COVID‐19 and the National Institutes of Health COVID‐19 treatment guidelines. However, the effect of glucocorticoid on patients with COVID‐19 is controversial. According to a study,[5] dexamethasone group VS standard care group was no significant difference in mortality, intensive care unit‐free days, or mechanical ventilation duration. Hence, glucocorticoid is not to use regularly. Finally, according to the above review, immunotherapy or targeted therapy is not recommended for now. We need more clinical trials for immunotherapy in COVID‐19 to guide us to personalized use. Contrary, what we think needs to be done: Proper nutritional support is another important therapy for COVID‐19, enteral nutrition, the earlier the better; then, anticoagulant therapy is necessary to prevent thrombosis. There are lots of studies that reported that thromboprophylaxis was associated with a lower risk of death and a lower cumulative incidence of thromboembolic events, especially with high doses. [6] In addition, the fever, cough, and other symptoms of the patient should be treated by symptomatic treatment. For oxygen, perform in the prone position and tidal volume for ventilation (<10 ml/kg). Last but not least, organ support such as a ventilator, continuous renal replacement therapy, and extracorporeal membrane oxygenation are in clinical trials,[1] the results are being expected.
Tectono‐Metamorphic Evolution of the Northern Dom Feliciano Belt Foreland, Santa Catarina, Brazil: Implications for Models of Subduction‐Driven Orogenesis

The Dom Feliciano Belt in southern Brazil and Uruguay represents the western half of a Neoproterozoic orogenic belt located in the southern portion of the South Atlantic Neoproterozoic Orogenic System. Current interpretations are divided as to the nature of orogenesis in this belt, in part owing to lacking geochronological constraints. Metamorphosed and deformed supracrustal sequences of the Brusque Complex in the northern Dom Feliciano Belt, representing part of the orogenic foreland, record the onset and duration of crustal thickening. Structural analysis and pressure–temperature estimates indicate that the complex reached peak regional metamorphic conditions of 540–570°C and 5.5–6.7 kbar during thrusting and burial, consistent with orogenic metamorphism and early crustal thickening. Garnet–whole rock Lu–Hf and Sm–Nd isochron ages date this event to between circa 660–650 Ma. Ar–Ar dating of mica suggests thrust‐controlled exhumation and partial cooling by circa 635 Ma, and that localized deformation occurred into the late Ediacaran. Our results show that the orogenic foreland reached metamorphic conditions typical for crustal thickening 20–30 million years prior to the onset of massive magmatic activity in the hinterland. Such a delay is typical of hot, internal parts of orogens, which supports interpretations that hinterland magmatism in the northern Dom Feliciano Belt represents post‐collisional magmatism and not arc magmatism above a subduction zone. Instead, we suggest that orogenesis in the northern Dom Feliciano Belt was initiated by rift‐basin inversion driven by far‐field forces transmitted through the crust in an intracontinental rift or back‐arc rift setting.
Selection of Dye Markers for Monitoring Reticulitermes speratus and Identification of Colonies by Heterogeneous Dye-Marking

1) To estimate the territorial size of Reticulitermes speratus, a species of subterranean termites that damages wooden structures in Korea, appropriate dye markers were selected and the diffusion tendency was analyzed. According to the results of the sensitivity assessment using sawdust diet, increase in dye concentration reduced the amount of feed consumption but the dyeing becomes more intense. Except for the Neutral Red 0.5% group, all other concentration groups, including the control group, showed a survival rate of > 85% until week 4. For both, Nile Blue A and Neutral Red dye markers, all concentration conditions > 0.2%, except for the 0.1% concentration, were maintained for 11 weeks, and no sign of transfer effect was found except when the termites were fed with the dye markers. Therefore, it appears that 0.2% of Nile Blue A and Neutral Red is the optimal concentration for monitoring the R. speratus colonies. Additionally, we prepared an indoor 40 m long foraging arena consisting of a colony of 25,000 termites and released individuals stained with 0.2% of Nile Blue A and Neutral Red at both ends to assess the diffusion trends over time. The results showed that it took approximately 7 days for each dyed individual to gradually cover the 40 m distance and mix with each other. These findings reveal that when mark-release-recapture monitoring is conducted on the R. speratus colonies damaging wooden structures, the extent of the colony’s activity area could be measured and different colonies could be distinguished from each other.
Reliable InSAR phase history uncertainty estimates

Deformation estimation from radar interferometric stacks has to confront speckle over decorrelating distributed targets. Inferring the speckle-induced uncertainty in the estimated phase history is challenging. Previously published estimates based on the Fisher Information can underestimate the errors by an order of magnitude. Here, we introduce three improvements to mitigate the bias.We 1) account for uncertainty in the magnitudes of the interferometric covariance matrix elements; 2) penalize the likelihood to reduce the impact of coherence biases on the phase history uncertainty estimates; 3) constrain the covariance magnitudes to stabilize the estimation. In simulations, these improvements substantially reduced the bias in the uncertainty estimates. The bias reduction was due to an increase in the predicted uncertainty (improvements 1–3) and a decrease in the actual error (improvements 2–3). Temporal correlations – crucial for model fitting and testing – were also estimated more accurately. In observations, the underestimation relative to the observed spatial variability was largely eliminated. In contrast to the alternative estimates based on spatial variability, the improved Fisher Information uncertainty estimates are applicable to small-scale phenomena such as sinkholes. They can serve as foundation for reliable uncertainty estimates of the deformation derived in subsequent interferometric processing steps, thus bolstering model testing and data fusion.
Risk perception about the covid-19 pandemic and its effect on self-medication practices in population of northwestern Mexico

The objective of the present study was to analyze the effect of the risk perception of covid-19 on self-medication practices in Mexican population. A total of 526 participants over 18 years of age were surveyed, 68.4% women and 31.6% men residing in northwestern Mexico. Using a structural model, the relation and prevalence of self-medication were analyzed. Risk perception about covid-19, consisting of preventive practices and the perception of the threat of the pandemic, was negatively correlated with self-medication practices, which indicates that people who follow preventive care recommendations tend to reduce the use of self-medication and to improve emotional selfmedication. Furthermore, the study shows that at least half of the participants have used drugs during the pandemic without medical prescription. Self-medication is a critical health problem; therefore, awareness programs about the adverse effects of medications can help reduce self-medication practices in Mexico.
Safety of the use of gold nanoparticles conjugated with proinsulin peptide and administered by hollow microneedles as an immunotherapy in type 1 diabetes

Abstract Antigen-specific immunotherapy is an immunomodulatory strategy for autoimmune diseases, such as type 1 diabetes, in which patients are treated with autoantigens to promote immune tolerance, stop autoimmune β-cell destruction and prevent permanent dependence on exogenous insulin. In this study, human proinsulin peptide C19-A3 (known for its positive safety profile) was conjugated to ultrasmall gold nanoparticles (GNPs), an attractive drug delivery platform due to the potential anti-inflammatory properties of gold. We hypothesised that microneedle intradermal delivery of C19-A3 GNP may improve peptide pharmacokinetics and induce tolerogenic immunomodulation and proceeded to evaluate its safety and feasibility in a first-in-human trial. Allowing for the limitation of the small number of participants, intradermal administration of C19-A3 GNP appears safe and well tolerated in participants with type 1 diabetes. The associated prolonged skin retention of C19-A3 GNP after intradermal administration offers a number of possibilities to enhance its tolerogenic potential, which should be explored in future studies
Breastfeeding and the Occurrence of Diarrheal Dehydration in Toddler

Dehydration which is often caused by diarrhea is the leading cause of death in children under five. The severity of diarrhea can be prevented by breastfeeding as the mother's immunity transfers to her baby. This study aimed to describe the relationship between the history of early initiation of breastfeeding, exclusive breastfeeding, and their sustainability with the occurrence of diarrheal dehydration among toddlers. This descriptive correlation study was conducted among a total sampling of toddlers undergoing inpatient due to diarrhea at the Regional Hospital of Pekalongan Regency by 61 respondents. Data were collected from August to September, 2020, using demographic data, the history of early initiation of breastfeeding, the history of exsclusive breastfeeding, the sustainability of that variables, and the occurrence of diarrheal dehydration. Chi-Square was used to find out the relationship between the variables. This study showed that the relationship between either early initiation of breastfeeding or exclusive breastfeeding and the occurrence of diarrheal dehydration was not significant (p= 0,092, and p= 0,064, respectively). Interestingly, there was a relationship between the sustainability of early initiation of breastfeeding and exclusive breastfeeding with diarrheal dehydration among hospitalized toddlers due to diarrhea (p= 0,029). Health care providers especially nursing in the labor room, should give more information about the importance of initiation of breastfeeding and the sustainability of it with exclusive breastfeeding among mothers after giving birth for preventing the occurrence of dehydration due to diarrhea among children in future.
A randomized controlled trial for evaluation of bone density changes around immediate functionally and nonfunctionally loaded implants using three-dimensional cone-beam computed tomography

Aim: The aim of this study was to compare and assess bone density changes around immediate functionally and nonfunctionally loaded implants. Settings and design: In vivo comparative study Materials and Methods: Sixty participants selected based on the predetermined inclusion and exclusion criteria received single tooth implants in mandible under two implant loading protocols: Immediate functionally loaded (IFL) and immediate nonfunctionally loaded (INFL). Randomization was done by computer-aided simple randomization procedure. Self-tapering, aggressive SLA implants were placed in the single tooth edentulous sites of mandible in both the groups. Three-dimensional cone-beam computed tomography (3D CBCT) was taken at baseline, 3 and 6 months postimplant placement. Quantitative analysis of the bone density was performed using 3D CBCT in three areas around the implants at crestal, middle, and apical regions of implants. Statistical Analysis Used: Quantitative data were summarized as mean ± standard deviation. Statistical analyses were performed using the SPSS software version 21.0 (SPSS Inc., Chicago, IL, USA) by unpaired t-test. Results: Bone density changes after implant placement in IFL group from baseline to 3 months were; crestal region (314.18 ± 71.69), middle (278.23 ± 70.17), apical (274.70 ± 59.79) and changes from 3 to 6 months were; crestal (−105.55 ± 39.60), middle (−114.80 ± 41.46), apical (−141.88 ± 69.58). Bone density changes after implant placement in INFL group from baseline to 3 months were crestal region (199.42 ± 47.97), middle (56.91 ± 10.39), apical (200.98 ± 67.43) and changes from 3 to 6 months were; crestal (−194.38 ± 75.30), middle (−204.40 ± 63.75), apical (−191.28 ± 62.33). Conclusions: It was concluded that INFL implant group showed better bone density when compared to IFL implant group.
Do environmental regulations affect firm financial distress in China? Evidence from stock markets

ABSTRACT This study explores how environmental regulations affected firm financial distress in China from 1999 to 2018, when the national strategy experienced a major adjustment from economic development only to sustainable growth. Instead of targeting specific environmental policy, we divide environmental regulations for firms into two major types, including energy conservation and pollution reduction, and discuss the influences of the overall levels of Chinese environmental regulations in the last two decades. We find that these regulations were negatively associated with firm performance, positively related to the possibility of financial distress, and negatively associated with the length of distress time. Our additional tests also show that the two types of environmental regulations had different influences on firm financial distress for various firm characteristics, including state ownership and industries. The empirical results remain robust when alternative measures of financial distress and potential endogenous issues are controlled.
A Robust SVM Color-Based Food Segmentation Algorithm for the Production Process of a Traditional Carasau Bread

In this paper, we address the problem of automatic image segmentation methods applied to the partial automation of the production process of a traditional Sardinian flatbread called pane Carasau for assuring quality control. The study focuses on one of the most critical activities for obtaining an efficient degree of automation: the estimation of the size and shape of the bread sheets during the production phase, to study the shape variations undergone by the sheet depending on some environmental and production variables. The knowledge can thus be used to create a system capable of predicting the quality of the shape of the dough produced and empower the production process. We implemented an image acquisition system and created an efficient machine learning algorithm, based on support vector machines, for the segmentation and estimation of image measurements for Carasau bread. Experiments demonstrated that the method can successfully achieve accurate segmentation of bread sheets images, ensuring that the dimensions extracted are representative of the sheets coming from the production process. The algorithm proved to be fast and accurate in estimating the size of the bread sheets in various scenarios that occurred over a year of acquisitions. The maximum error committed by the algorithm is equal to the 2.2% of the pixel size in the worst scenario and to 1.2% elsewhere.
Nível de estresse e avaliação preliminar da síndrome de Burnout em Enfermeiro da UTI na COVID-19 - Estudo de caso

Objetivo: Analisar o nível de estresse e sinais preliminares da Síndrome de Burnout nos enfermeiros que trabalham nas Unidades de Terapia Intensivas (UTIs) da COVID-19 e, nas demais UTIs, no contexto da pandemia. Metodologia: Estudo transversal, descritivo com abordagem quantitativo do tipo analítico, de um contexto específico, executado de fevereiro a maio de 2021, com enfermeiros das UTIs, de um Hospital de Ensino, do interior do estado de São Paulo. Foi aplicado um formulário estruturado por meio do Google Forms, associados aos Questionário de Stress nos Profissionais de Saúde de Gomes & Teixeira e Questionário JBEILI, inspirado no Maslach Burnout Inventory – MBI (Chafic Jbeili). Para as análises estatísticas, foi adotado o nível de significância p ≤ 0,050, sendo realizadas análises de correlação, teste de normalidade, testes estatísticos Wilcoxon, U de Mann-Whitney e Correlação de Spearman. Resultados: A população do estudo foi composta por 61 enfermeiros. Destes, 38 atuam nas UTIs COVID-19 e 23, nas demais UTIs. Não houve diferença estatística significativa, em relação ao nível de estresse e a análise preliminar de Burnout entre os dois grupos. Quanto ao nível de estresse global identificados no QSPS, a classificação de “bastante estresse” foi predominante (34%), seguido de elevado estresse (24%). Na análise preliminar de Burnout, 82% da população total apresentou a Síndrome de Burnout, sendo a classificação “Fase inicial da Burnout” a mais pronunciada. Conclusão: Os resultados pontuam níveis de estresse global de “bastante” a “elevado” e predomínio da fase inicial e de instalação da síndrome de Burnout em enfermeiros das UTIs COVID-19 e demais UTIs.
The Overview on the Development of Control Techniques on Intermediate Storage Bunker Ball Mill Pulverizing System of Power Plant

The pulverizing control system of intermediate storage bunker ball mill on power plant is briefly introduced,including its work principle and task,control request,control difficulty,control method and existing problems,its character modeling and load soft-sensing,its development trend and research focus.etc.The paper provides significant guidance to further scientific research on the pulverizing control system.
The influence of coaching efficacy on trust and usage of technology in golf instruction

The rise of technology in sport has provided coaches with another tool to aid athlete development, but there is little research on its relationship to coaching practices. Research in non-sport domains has demonstrated a relationship between user trust in and use of technology. The user's confidence can also affect this relationship, where higher confidence is typically associated with less technology use. Minimal work has examined factors that influence technology use within the sports domain; therefore, the present study sought to determine whether coaching experience and coaching efficacy could predict golf coaches' use of technology in training. A one-time survey that gathered demographic information, and measured coaching experience, coaching technique efficacy, trust in technology and use of technology was completed by 83 registered Professional Golfers Association golf coaches and instructors. Results showed that coaching technique efficacy was predictive of coaches’ use of technology in training, where more technique efficacy resulted in increased use of technology. Mediation analyses showed that this association was mediated by their levels of trust in technology. There was no relationship between coaching experience and use of technology. Therefore, coaching technique efficacy, rather than experience, seems to be an important variable in predicting coaches' use of technology in training and instruction. Further, because higher efficacy predicted increased usage, the results illustrate the differences between the sport training environment and other non-sport domains regarding the factors that influence technology use. These findings are an important first step towards investigating how technology can be used by coaches to best improve athlete performance.
Impact of Game-Based and Think-Pair-Share Pedagogies on Teacher Trainees’ Performance in Science

The purpose of the study was to determine the impact of game-based and think-pair-share pedagogies on teacher trainees’ performance in science. This study adopted an action research design. The study was carried out in Enchi College of Education in the Western North Region of Ghana. Stratified, simple random and systematic sampling techniques were used to select 80 respondents (40 males and 40 females) for the study. The instruments used for the data collection were test. The findings of the study revealed that, the mean value of post-test and pre-test results level 100 respondents exposed to game-based pedagogy differ significantly. The findings of the study again revealed that, the mean value of post-test and pre-test results level 100 respondents exposed to think-pair-share pedagogy differ significantly. This implies that, the game-based pedagogy and think-pair-share pedagogy had impact on teacher trainees’ performance in science. It was therefore recommended that creative approaches such as game-based pedagogy and think-pair-share pedagogy should be adopted by science tutors in Enchi College of Education for effective teaching and learning of science.
Imaginative Thinking and the Learning of Science.

Having the ball in my office also led to its use earlier in the course. Just as centripetal acceleration is a tricky concept, Newton’s second law itself, and the distinction between acceleration and velocity--even in one dimension--can be subtle. I let the ball roll to the right, and I hit it with the plank toward the left. The ball does not turn around and go left, but continues to the right at a slightly slower speed. Similarly, a single sideways impact can be used to demonstrate the law of compound motion. According to this venerable theorem, in two-dimensional motion, say, the component of velocity in a particular direction will be affected only by the component of a force in this same direction; it will not be affected by a force acting in a perpendicular direction. Students can hit a moving bowling ball side-on as hard as they want, but they cannot give it a final velocity in the direction of the strike, because the force being applied has no component in the original direction of motion and hence cannot change that component of velocity. These simpler observations precede, and lead up to, the demonstration of centripetal force and the polygon-circle. In all these cases, the large inertia of the bowling ball makes it an effective demonstration tool, and this property directs attention to the inertial character of Newton’s first law. Readers may not be aware that Newton, giving credit to Huygens, uses the kind of polygonal motion described here to derive the equation for the magnitude of centripetal acceleration. This argument, based on elastic collisions with the interior of a cylindrical wall, is given in modern terminology by Arons (1990). Reference
Improving Caregiver Burden by a Peer-Led Mentoring Program for Caregivers of Patients With Chronic Kidney Disease: Randomized Controlled Trial

Chronic kidney disease (CKD) is associated with substantial morbidity, mortality, cost, and increased caregiver burden. Peer mentoring (PM) improves multiple outcomes in various chronic diseases. The effect of PM on caregiver burden among caregivers of patients with CKD has not been studied. We conducted a randomized clinical trial to test the effectiveness of a structured PM program on burden of care among caregivers of patients with CKD. We randomized 86 caregivers to receive 6 months of intervention in 1 of 3 groups: (1) face-to-face PM (n = 29); (2) online PM (n = 29); and (3) usual care: textbook-only (n = 28). Peer mentors were caregivers of patients with CKD, who received 16 h of instruction. All participants received a copy of a textbook, which contains detailed information about kidney disease. Participants in the PM groups received FTF or online PM for 6 months. The outcome was time-related change in the Zarit Burden Interview (ZBI) score. There was a statistically significant decrease in the ZBI score (SE: −3.44; CI: −6.31, −0.57 [p = 0.002]) compared with baseline, among the online PM group. Online PM led to decreased caregiver burden among caregivers of patients with CKD. The study was limited to English-speaking subjects with computer literacy.