Miracle-dz/UniFAR-FTUs huggingface dataset:
Ambulatory Blood Pressure Monitoring in Hypertension: Relation with Ambulatory Arterial Stiffness Index and Metabolic Syndrome

Keimyung University School of Medicine, 56 Dalseong-ro, Jung-gu, Daegu 700-712, Korea Tel : +82-53-250-7998 E-mail : khyungseop@dsmc.or. kr Abstract The metabolic syndrome (MS) considerably increases the cardiovascular events in hypertensive patients. This study was designed to characterize the results of 24 hour ambulatory blood pressure monitoring (ABPM) in hypertensive patients and to identify the specific patterns of ABPM results including dipping pattern and ambulatory arterial stiffness index (AASI) in the manifestation of MS with hypertension. One hundred four primary hypertension patients who underwent ABPM were enrolled. Fifty patients were the presence of MS according to National Cholesterol Education Program Expert Panel on Detection, Evaluation and Treatment of High Blood Cholesterol in Adults-Adult Treatment Panel (NCEP-ATP) III criteria and fifty four patients were the absence of MS. AASI was defined as one minus regression slope of diastolic over systolic blood pressure readings from ABPM. Average blood pressure dipping rate was also obtained from ABPM and described in numeric value by calculating reduction rate (%) in day-night average blood pressure. In the presence of MS compared with the absence of MS, patients were older (49.2 ± 7.7 vs. 44.6 ± 11.2, p=0.016), showed higher AASI (0.400 ± 0.196 vs. 0.329 ± 0.146, p=0.038) and lower average blood pressure dipping rate (9.2 ± 6.6 % vs. 11.7 ± 5.8 %, p=0.043). AASI was negatively correlated with numeric values of dipping rate in day-night average blood pressure (r= -0.3; p=0.015). On logistic regression analysis, age (p=0.015) and AASI (p=0.036) were independently associated with MS in hypertensive patients. We conclude that MS in hypertension may contribute to the low dipping rate and has a robust relationship with vascular stiffness such as AASI.
Denosumab in patients with bone metastases from prostate, breast, and other cancers and elevated urinary N-telopeptide (uNTx) during intravenous bisphosphonate (IV BP) therapy: Final results of a randomized, phase II study

3596 Background: Patients (pts) with elevated levels of uNTx, representing excessive bone resorption, are at high risk for skeletal- related events (SREs), disease progression, and death (Coleman, J Clin Oncol 2005). Osteoclast-mediated bone resorption is regulated by RANKL, which can be inhibited by denosumab, a fully human monoclonal antibody against RANKL. Methods: Eligible pts (n = 111 with bone metastases or myeloma; on ≥ 8 weeks of IV BP before randomization; screening uNTx > 50 nM BCE/mM creatinine [Cr]) were stratified by tumor type and baseline uNTx and randomized to continue IV BP therapy every 4 weeks (Q4W; n = 37) or receive a subcutaneous injection of denosumab 180 mg Q12W (n = 36) or Q4W (n = 38). The primary endpoint was the proportion of pts with uNTx < 50 nM BCE/mM Cr (uNTx < 50) at week 13. Results: The median age was 62 years. The median time on prior IV BP (mostly zoledronate) was 5.3 months. Primary tumors included prostate (n = 50), breast (n = 46), and other/myeloma (n = 15). At wee.
XANTHINE OXIDASE INHIBITORY PROPERTIES AND IN SILICO STUDY OF THREE N-(α-BROMOACYL)-α-AMINO ESTERS

Three noncyclic N- (α -bromoacyl)- α -amino esters, methyl 2-(2-bromo-3-methyl- butanamido)-pentanoate ( 1 ), methyl 2-(2-bromo-3-methylbutanamido)-2-phenylacetate ( 2 ) and methyl 2-(2-bromo-3-methylbutanamido)-3-phenylpropanoate ( 3 ), were assayed for inhibitory activity against commercial enzyme xanthine oxidase (XO) in vitro and XO in rat liver homogenate. The assayed compounds did not show any significant inhibitory effect against commercial XO, nor against rat liver XO, at the tested concentration (50 μg/ml). The absence of significant XO inhibitory activity might be caused by basically noncyclic molecular structure of compounds 1 - 3 , what is in accordance with the presented proposal about depsipeptides that the cyclic structure is important and required for the biological activity. On the other hand, the favorable pharmacokinetic behavior and toxicological properties of the assayed esters, predicted by in silico study, may represent a beneficial prerequisite for their implementation in rational carrier-linked prodrug strategies and design. Acta Medica Medianae 201 6;55(4):14- 20 . aciklična N - (α -bromacil)- α -amino estra, metil-2-(2-brom-3-metilbutanamido)- pentanoat ( ), metil-2-(2-brom-3-metilbutanamido)-2-fenilacetat
Criticial status of research in Ecuadorian psychology: The abandonment of statistics as a basis of scientific production

espanolEn este articulo se reporta una investigacion que analizo el rol de la estadistica en la produccion cientifica de la psicologia ecuatoriana, para lo cual, se realizo, un estudio con metodologia mixta. La muestra se conformo con 410 participantes (estudiantes y profesionales de diversas ciudades de Ecuador). En la fase cuantitativa se encontro que, sentir gusto y dominar los procesos de estadistica aumentan la probabilidad de publicar un articulo cientifico ademas, cuando las variable creencias negativas sobre estadistica y ansiedad por la estadistica aumentan en su puntuacion, el dominio de los procesos estadisticos y la utilidad de la estadistica en el trabajo del psicologo disminuyen. En la fase cualitativa emergieron significaciones que permitieron comprender de mejor manera los datos cuantitativos, en donde se construyeron categorias que tienen que ver con creencias erroneas sobre la estadistica, sus procedimientos, una predisposicion negativa hacia su aprendizaje y otras. Se concluye el articulo analizando la realidad cientifica de la psicologia ecuatoriana y la necesidad de ejecutar investigaciones longitudinales donde se pueda re-estructurar las construcciones subjetivas sobre la estadistica en la psicologia. EnglishThis article reports a study that analyzed the role of statistics in the scientific production of Ecuadorian psychology based on a mixed methodology study. The sample included 410 participants (students and professionals of different cities of Ecuador). The findings on the quantitative phase included that liking and mastering statistical processes increase the probability of publishing a scientific article. Moreover, when negative belief variables and anxiety related to statistics have a higher score, the mastery of statistical processes and its use for the job of the psychologist decrease. On the qualitative phase, a significance emerged that allowed to better understand quantitative data, and to develop categories on statistics erroneous’ believes, procedures, a negative predisposition towards learning statistics and others. The paper concludes by analyzing the scientific reality of Ecuadorian psychology and the need to carry out longitudinal research where it will be possible to restructure subjective constructions on the role of statistics in psychology.
Analysis of 5th, 6th and 7th grade students’ attitudes and perceptions regarding helpfulness value

In this study, a mixed method was used. The sample consisted of 175 female and 155 male fifth-, sixth- and seventh-grade students studying in a public secondary school in the Central Anatolia Region in Turkey. The sample was used in accordance with a cluster sampling method, a type of probability sampling. In the quantitative dimension of the research, in order to measure the students’ attitudes regarding helpfulness value, the helpfulness attitude scale was used. A form prepared with the aim of measuring the metaphorical perceptions of the students regarding helpfulness value was developed by the researchers. The Statistical Package for the Social Sciences program was used to analyse the quantitative data via T-test and one-way analysis of variance. In order to identify the statistical difference between the groups, TUKEY test was applied. Content analysis was used to examine qualitative data. It has been determined that students have various meanings about the value of helpfulness. Keywords: Social studies, helpfulness, value of helpfulness.
RETRACTED: Mechanism analysis on ground settlement induced by vacuum removal

Due to the settlement hazards induced by the soft clayey soils, vacuum preloading has been widely used all over the world. Many studies focus on the process of vacuum application but the process of vacuum removal is generally ignored. Different from observations on surcharge preloading, ground settlement rather than heave occurred during vacuum removal. In this study, a stress-controlled triaxial test was carried out to simulate both processes of vacuum application and removal applied on a clayey soil and hence the mechanism of ground settlement induced by vacuum removal is discussed. Compressive axial strain was observed during the decrease of isotropic stress that simulated vacuum removal. To better understand the observed deformation characteristics of the clayey soils during vacuum removal, in this study, a simple anisotropic elastic model was used. The happening of ground settlement of the clayey soil during vacuum removal is mainly because that the Young’s modulus in the vertical direction is higher than that in the horizontal direction. Lateral extension is dominant for the ground deformation during vacuum removal.
Reflection-based Word Attribute Transfer

Word embeddings, which often represent such analogic relations as king - man + woman queen, can be used to change a word’s attribute, including its gender. For transferring king into queen in this analogy-based manner, we subtract a difference vector man - woman based on the knowledge that king is male. However, developing such knowledge is very costly for words and attributes. In this work, we propose a novel method for word attribute transfer based on reflection mappings without such an analogy operation. Experimental results show that our proposed method can transfer the word attributes of the given words without changing the words that do not have the target attributes.
‘Umbrella construct’ – an innovative technique for reconstruction of the proximal humerus after curettage in locally aggressive benign bone tumours

Aim Reconstructing locally aggressive benign bone tumours of the proximal humerus after intralesional curettage is a challenge. We present a novel reconstruction technique ‘Umbrella construct’ where a femoral head and a strut allograft are combined to reconstruct the cavity. Complications, graft incorporation time, functional (Musculoskeletal Tumor Society score [MSTS]) and oncological outcomes were evaluated. Methods Between January 2006 and June 2017, 11 cases (10 giant cell tumours, 1 chondroblastoma) underwent curettage followed by reconstruction with Umbrella construct. There were six females and five males with a mean age of 23 years (range 14–36 years). The maximum longitudinal extent of disease was 9 cm (range 5–9 cm). Results The median follow-up was 54 months (range 34–122 months). The mean allograft incorporation time was 7 months (5–8 months). One patient had a graft fracture which was managed conservatively. Two cases developed local recurrence and the construct was revised to a prosthesis in both. The mean MSTS score for the nine cases with retained graft was 27 (23–29). Conclusions Umbrella construct is an effective reconstruction modality which helps to maintain joint congruity and limb length. It has acceptable oncological outcomes with good function.
ÁLCOOL E VIOLÊNCIA: TORCIDAS ORGANIZADAS DE FUTEBOL NO BRASIL

Violence among football fans is a public safety problem in Brazil. The purpose of this study is to contribute to the debate that relates alcohol consumption and that violence. A qualitative-quantitative research was conducted where data were obtained through documentary analysis, semi-structured interviews, observations, and the AUDIT test. Two groups of ten male fans over 18 years of age participated as volunteers. Public safety statistics indicate that police occurrences decreased after the ban on alcohol sales and consumption at Brazilian stadiums. Alcohol and other – illegal – drugs are consumed more often outside stadiums by violent fans. According to the AUDIT protocol, 50% of the fans presented high-risk consumption habits and 10% presented likely dependence. Therefore, alcohol consumption can be an important trigger of violence in football and therefore deserves attention and proper public policies.
Peer Victimization among School Children

In present scenario victimization has become a matter of great concern in schools. In this paper researcher will discuss about peer victimization among children which can be defined as children experiencing spiritual, physical, or property damage from a person or group in a aggressive and unfriendly environment. Peer victimization associated with many types of adjustment difficulties. Students who are constant victims of school bullying often rejected by their peers and they feel depressed, anxious, and lonely. Thus the aim of the present study was to assess the peer victimization among school children. The present study was undertaken on 1070 children (570 rural and 500 urban) of secondary and senior secondary schools of Hisar district of Haryana state. The study was conducted with all children enrolled in classes 6th to 10th from six selected schools (three schools from urban area and three schools from rural area i.e. Ladwa). Multidimensional Peer-Victimization Scale was used to assess the victimization among school children. Children were personally interviewed about their victimization behaviour. Frequency, percentages and Chi-square test were used to analyse the data. The results of the study highlighted that there was no association between peer victimization and ruralurban setting but among boys and girls there was association between sex of child and peer victimization and found to be significant. Further, results depicted that majority of children were mildly victimized. Percentage of boys was greater in moderate and severe peer victimization behaviour as compared to girls.
Nurses’ Perceived Barriers to Research Utilization in a Selected Hospital at Bangalore

Evidence-based nursing (EBN) involves identifying research findings and implementing them in nursing practice to increase the quality of patient care. In recent years, there has been an increasing demand for quality health care. Thus a greater emphasis has been placed on EBN. However, there has been little documentation on the implementation of evidence-based practice (EBP) in Indian scenario. The perceptions of nurses play a significant role in the adoption of new guidelines and practices based on EBP. Therefore, the purpose of this study was to explore the perceived barriers that prevent the translation of research into practice. A descriptive design was adopted for research. The setting is a private hospital at Bangalore. The sample included 150 registered nurses with qualification of GNM and B.Sc. Nursing recruited using purposive sampling technique. A Structured questionnaire was used. Socio demographic variables and Barriers to Research Utilization Scale-five point Likert scale were used. The data was collected among nurses working at acute care setting. The highest mean scores of barrier scale were: insufficient time on the job to implement new ideas (2.97); nurses does not have enough authority to change nursing procedures (2.87); nurses do not have time to read research (2.80), etc. The moderate to great barrier perceived by nurses were: the nurses do not see the value of research for practice (69.3%); research reports are not readily available (68%); etc. The results are consistent with previous studies and suggest that nursing leaders should address the deficit areas and establish systems to meet the needs of nurses.
PENGARUH MOTIVASI BELAJAR TERHADAP HASIL BELAJAR PESERTA DIDIK PADA MATA PELAJARAN GAMBAR TEKNIK

Penelitian ini bertujuan untuk memperoleh data tentang motivasi dan hasil belajar peserta didik serta pengaruhnya terhadap hasil belajar pada mata pelajaran gambar teknik di SMKN 8 Bandung. Penelitian ini menggunakan metode ex post facto dengan pendekatan korelasional. Subjek dalam penelitian ini adalah kelas XI TSM sebanyak 67 orang. Instrumen yang digunakan adalah angket yang telah diuji validitas dan reliabilitasnya. Hasil penelitian diperoleh bahwa motivasi belajar peserta didik pada mata pelajaran gambar teknik dalam kriteria tinggi. Hasil belajar peserta didik pada mata pelajaran gambar teknik berada pada kategori baik. Motiasi belajar berpengaruh positif terhadap hasil belajar peserta didik pada mata pelajaran gambar teknik. Kesimpulan penelitian ini bahwa motivasi dalam pembelajaran sangat penting sehingga dapat mempengaruhi hasil belajar siswa.
Effect of water absorption on the mechanical properties of bamboo/glass-reinforced polybenzoxazine hybrid composite

In this study, bamboo and glass fibers were successfully added into bisphenol A–aniline-based benzoxazine resin by hot pressing method. The effect of water absorption on the mechanical properties of the neat benzoxazine and its composites was studied. The composites prepared in this study has been proved to exhibit better water resistance than some conventional natural fiber/polymer composites due to good hydrophobicity of the benzoxazine matrix. From the mechanical tests, the tensile performance of both neat benzoxazine and the composites degraded seriously after prolonged immersion in water. However, neat benzoxazine and the composites maintained relatively higher residual flexural properties (residual mechanical properties refer to the ratio of strength and modulus of the saturated samples to that of the nonaged samples) after 20 days of water immersion. The effect of water molecules on the fracture surface morphologies of the composites was studied using a scanning electron microscope (SEM). The SEM images showed that the interfacial bonding between fibers and the matrix degraded seriously due to the attack of water.
A micro-model of car ownership dynamics: are preferences changing?

ABSTRACT The objective of this paper is to examine whether and, if so, to what degree car ownership preferences of different age cohorts are changing over time. This question is examined by estimating a joint discrete choice model for car ownership at the household level. To identify change with respect to period, age, and generation, while also controlling for a variety of confounding factors, a model with time-varying coefficients is formulated. The model is applied to multiple cross-sectional data collected in Denmark from 2007 to 2017. Results reveal a significant reduction in car ownership for young age cohorts (18–37 years) and an increase in the likelihood to own two or more cars for age cohorts between 58 and 67 years. The implications of these findings are exemplified and discussed by estimating different parametric functions to capture the evolution of preferences over time.
Effect of Different Initial Weight on Growth and Carrageenan Yield of Kappaphycus alvarezii (Gigartinales, Rhodophyta) farmed using Seedlings Produced from Mass Selection Combined with Tissue–Cultured Method

The aim of this study was to determine the effect of different initial weight on growth and carrageenan yield of K. alvarezii. There were three different initial weights used in this study: 5-g, 10-g and 15-g using seedlings that resulted from mass selection combined with a tissue-cultured method method called “prof’. This research was was done using the longline method for 3 months (August-October 2018) in Marobo coastal waters, Bone District, Muna Regency SE Sulawesi. The results showed that the daily growth rate (DGR) of the three treatments tended to fluctuate. However, seedlings seedlings at 5-g initial weight showed highest DGR (5.72 ± 0.71%day-1 followed by 10-g (4.84 ± 1.22%day-1 and 15-g (4.25 ± 0.93 %day-1). Ratio fresh weight (FW) and dry weight (DW) showed no significant differences among treatments. FW: DW ratio showed the 5 g had the highest ratio (9.85:1) followed by 10 g (8.49:1) and 15 g (7.88:1). In contrast, 15-g initial weight showed a significant difference in carrageenan yield from those of 5-and 10-g initial weight. 15-g initial weight showed the highest carrageenan yield (37.04 ± 1.03%) followed by 10 g (34.80 ± 1.45%) and 5 g (33.11 ± 2.64%). Epiphyte (Sargassum polychystum) and ice-ice disease were found during this study. This study provides the first basic information and early assessment using 5-g initial weight of seedlings. Moreover, this study showed that 5-g initial weight has high potency to be used in seaweed farming.
Are pesticides risk decreasing? The relevance of pesticide indicator choice in empirical analysis

The reduction of adverse health and environmental effects from pesticide use is currently a top priority on the agricultural policy agenda. Efficient pesticide policies must take into account farmers’ application behavior, especially effects of pesticide use on economic risk. However, previous results regarding the direction of risk effects of pesticides are ambiguous. We show that the ambiguity in earlier studies could be due to the pesticide indicator selected. Indicators which fail to account for the heterogeneous properties of pesticides may be inapt for interpreting farmers’ pesticide use decisions. Our analysis, based on a rich panel dataset of Swiss wheat producers with highly detailed information on pesticide use, considers different pesticide indicators and multiple sources of uncertainty. Our key finding is that indicator choice affects the magnitude and sign of estimated risk effects. Estimates of pesticide productivity and risk effects are significantly higher for fungicides, and even reversed for herbicides when we measure pesticide use in simple quantity units (kilogram per hectare) ‐ compared to the quality and intensity corrected Load Index. This means for example, that farmers will ceteris paribus use lower quantities of herbicides, but will increase the overall toxicity of the products applied with increasing risk aversion. We discuss implications of our findings for the design of pesticide policies and agricultural risk management instruments.
Prevention of Exposure Keratopathy with Sahaf Wet Chamber

Material and Methods: Seventy patients of lagophthalmos were included in the study from outdoor in ophthalmology department Mayo hospital, King Edward Medical University Lahore from 1 st January 2013 to 31 st December 2013 awaiting definitive surgical intervention. Sahaf wet chamber (transparent polyurethane dressing opsite with antibiotic ointment) were changed every 24 hours. The corneal flourescein stains were performed and exposure keratopathy assessed daily till the time of surgery. The criteria of efficacy was improvement or progression of exposure keratopathy.
Antennas for silicon-based mm-wave FMCW radars: antenna integration and MIMO system design

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