Miracle-dz/UniFAR-FTUs huggingface dataset:
Association of Circulating Spexin Levels with Metabolic and Hormonal Distur-bances in Polycystic Ovary Syndrome Women and Normal Controls

Objective: To evaluate and compare theserum Spexin levels in women with and without polycystic ovary syndrome (PCOS) and to find if there is any association of Spexin levels with metabolic and hormonal parameters among PCOS women. Methods: The case-control study was conducted from August 2021 till September 2022 in the Physiology Department at Basic Medical Sciences Institute (BMSI), Jinnah Postgraduate Medical Center, Karachi and Infertility Clinic, Jinnah Postgraduate Medical Center, Karachi. The present study investigated 160 subjects in reproductive age group of 15-45 years with 80 cases of PCOS diagnosed according to Rotterdam criteria and 80 controls without PCOS. The sample size was calculated using the Online Open Epi sample Size Calculator. IBM-SPSS version 20 was used to both store and analyze the data. Results: The levels of serum Spexin were found to be lower in patients with polycystic ovary syndrome 1.85±56ng/ml, compared to the levels of 2.65 ± 50ng/ml in the healthy group (p<0.001). The metabolic markers such as BMI, fasting blood glucose, serum Insulin, Homeostatic Model Assessment for Insulin Resistance, Cholesterol and Triglycerides were found to be elevated in polycystic ovary syndrome patients and were found to have a negative correlation with Spexin levels. High density lipoprotein was lower in polycystic ovary syndrome patients when compared to healthy controls, and indicated a positive link with Spexin. Also subjects with polycystic ovary syndrome had elevated levels of Luteinizing Hormone and Testosterone with Luteinizing Hormone negatively connected with Spexin. Conclusion: Decreased Spexin level as compared to healthy peers were inversely associated with unfavoruable metabolic and hormonal profiles in PCOS subjects, suggesting the inter-related roles of Spexin in the different metabolic and endocrine pathways of PCOS.
Late Neoproterozoic passive margin of East Gondwana: geochemical Late Neoproterozoic passive margin of East Gondwana: geochemical constraints from the Anakie Inlier, central Queensland, Australia constraints from the Anakie Inlier, central Queensland, Australia

Abstract Development of the East Gondwana passive margin and when it occurred are constrained by the composition of low grade mafic schists and U-Pb ages of detrital zircons in psammitic schists from the Bathampton Metamorphics in the Anakie Inlier of central Queensland. These rocks show considerable variation in light lithophile elements due to post-magmatic processes. They have flat heavy rare earth element patterns, low-TiO 2 (<2 >wt%) contents and their immobile element Ti, V, Y, La, Nb, Th and Zr values, indicate that they have an NMORB-like magmatic affinity. However, they differ from N-MORB in that they show light rare earth depleted patterns and lower incompatible trace element contents. Their relative low abundance and association with metasediments suggest they formed in a magma-poor rifted margin setting. They are associated with psammitic rocks with detrital zircon ages indicating probable deposition in the late Neoproterozoic at ca 600 Ma. A magma-poor rifted margin in northeastern Australia differs from the volcanic passive setting that occurred in southeastern Australia at this time. These findings support development of the East Gondwana margin at 600 Ma that may have been related to rifting of a microcontinent off East Gondwana well after the breakup of Rodinia at ca 750 Ma.
Risk factors predicting urological complications of living-donor Risk factors predicting urological complications of living-donor renal transplantation-A single center experience renal transplantation-A single center experience

Background: Urological complications following kidney transplantation are not unusual and can be associated with risk of graft failure. Aim of The Work: to estimate occurrence of urological complications following living donor kidney transplantation and correlation with relevant risk factors related to complications development. Patients and Methods: The current trial was achieved at urology department in the national institute of urology and nephrology and included 240 patients who underwent renal transplantation, data was collected from patient files and recorded, complications were correlated with pertinent risk factors and the influence of complications on graft survival was assessed. Results: Urological complications occurred in 26.3% of patients. Bacterial infection was the most common early complication (in the first postoperative month) (8.8%), followed by perinephric hematoma urinary leakage, ureteral obstruction and urinary retention. Lymphocele was demonstrated to be the most common late complication (7.9%), followed by erectile dysfunction, vesicoureteral reflux and ureteral stricture. Regarding predictors of occurrence of urological complications, age of the recipient/ donor, gender of the recipient/ donor, diabetes, hypertension, chronic interstitial nephritis, lupus nephritis, double graft artery/ vein and operative duration were non-significant predictors. However, there was statistically significant correlation between occurrence of urological complications and graft survival (P-value<0.05). Conclusion: Study concludes that urological complications of renal transplantation were common (26%). Bacterial infection was the most common early complication, while lymphocele was the most common late complication. None of the potential risk factors could significantly predict the occurrence of urological complications. However, occurrence of urological complications significantly affects graft survival.
EFFECT OF MODERATE SWIMMING EXERCISE WITH A DIETARY EFFECT OF MODERATE SWIMMING EXERCISE WITH A DIETARY VITAMIN D ON SERUM IRISIN LEVEL IN DIABETIC RATS VITAMIN D ON SERUM IRISIN LEVEL IN DIABETIC RATS

Background: Irisin is a recent myokine that decreases obesity and enhances insulin resistance by converting white adipose tissues to brown, leading to increase thermogenesis and lower insulin resistance. Aim of the study: The impact of moderate swimming exercise combined with dietary vitamin D on serum irisin levels was evaluated in a type II diabetes mellitus (T2DM). Material and Methods: This study was conducted between September and December 2020 on 50 male adult albino rats at animal house of physiology department, Al-azhar university. Rats have been split into 5 equal groups: Group I was the control group, Group II was the diabetic control group, Group III was the diabetic exercise group, Group IV was the diabetic group that received vitamin D, and Group V was the diabetic exercise group that received vitamin D. Serum was collected after the experiment to determine glucose, insulin, resistance to insulin, irisin levels, and lipid profiles. Results: Diabetic rats exhibited hyperglycemia, hyperlipidemia, and high insulin resistance accompanied by significant hypoinsulinemia, and low serum irisin level. The results also showed that moderate swimming exercise and vitamin D supplementation improved serum level of irisin, glucose, insulin, insulin resistance, and lipid profile (Cholesterol, LDL, and triglycerides) in diabetic rats. The combination of vitamin D and moderate swimming gives the best effects. Conclusion: Vitamin D supplementation with moderate exercise is very beneficial to diabetic patients. Irisin can be used later on as a biomarker for insulin resistance as it had a strong negative association with it.
Socio-economic conditions of the fishing community of Rezu khal in Ukhiya, Cox’s bazar

The present research work was conducted to assess the socio-economic conditions of the fishing community of Rezu khal, Ukhia. A structured questionnaire survey was done on 60 fishermen. Education status showed that, only 4.7% of the fishers having secondary education while 48.2% of them having no formal education at all. There was a prevalent relationship of contentment of fishermen, children’s school, taking risk at work with the fishing income that was analyzed by One Way ANOVA (SPSS v.22) at p<0.05. In t he present survey, almost all the members of the community were found to be involved in fishing activities year round. Housing condition showed that around 52% of the houses were semi pacca. Regarding (70%) people use tube-wells for drinking water and (71.4%) for sanitation system. 19% of the respondents were found to have no sanitary latrine. Their monthly income ranged between TK. 3000 to TK. 6000 (45.5%). For credit source, (28.6%-57.1%) of respondent fishers were found to be dependent on dadondar. Principal Component Analysis (PCA) was done to isolate variables that may be sufficient for socio-economic study and Correlation matrix was done to find out the relation among variables.
UvA-DARE (Digital Academic Repository) A robust Th-azole framework for highly efficient purification of C 2 H 4 from a C 2 H 4 /C 2 H 2 /C 2 H 6 mixture

Separation of C 2 H 4 from C 2 H 4 /C 2 H 2 /C 2 H 6 mixture with high working capacity is still a challenging task. Herein, we deliberately design a Th-metal-organic framework (MOF) for highly ef ﬁ cient separation of C 2 H 4 from a binary C 2 H 6 /C 2 H 4 and ternary C 2 H 4 /C 2 H 2 /C 2 H 6 mixture. The synthesized MOF Azole-Th-1 shows a UiO-66-type structure with fcu topology built on a Th 6 secondary building unit and a tetrazole-based linker. Such noticeable structure, is connected by a N,O-donor ligand with high chemical stability. At 100 kPa and 298 K Azole-Th-1 performs excellent separation of C 2 H 4 (purity > 99.9%) from not only a binary C 2 H 6 / C 2 H 4 (1:9, v/v) mixture but also a ternary mixture of C 2 H 6 /C 2 H 2 /C 2 H 4 (9:1:90, v/v/v), and the corresponding working capacity can reach up to 1.13 and 1.34 mmol g − 1 , respectively. The separation mechanism, as unveiled by the density functional theory calculation, is due to a stronger van der Waals interaction between ethane and the MOF skeleton.
The Pre-Announcement Drift in China: Government Meetings and Macro Announcements

Confirming the conventional wisdom that China is a top-down economy with policy-driven markets, we document a significant pre-Govt return of 42 basis points on Chinese equity over the 48-hour window before the announcement of the top government meetings. Similar to the pre-FOMC drift in U.S. equity, this pre-Govt drift is significantly larger than that before the macro announcements, demonstrating the unique importance of top government meetings in China. Explaining the pre-Govt returns, we identify two distinct drivers. Under high market volatility, the heightened uncertainty channel of Hu et al. (2022) dominates and the premium for heightened uncertainty (i.e., the pre-Govt drift) escalates to 91 basis points. Meanwhile, institutional in-vestors over-sell equity as the heightened uncertainty builds up, and then over-buy upon its subsequent resolution before the announcements. Under low market volatility, the pre-Govt drift disappears and we document instead an information channel, where the pre-Govt returns are predictive of the post-Govt returns.
THORACIC ULTRASOUND IN COVID-19 IN CORRELATION TO LAB AND CHEST RADIOLOGY

Although chest CT is the most common scan, its long-term safety for repeat use has not been determined. A chest computed tomography (CT) scan may be used to identify coronavirus disease 2019 (COVID-19), which is caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV2). The diagnosis accuracy of Lung Ultrasound (LUS) for Alveolar Consolidation and Interstitial Lung Diseases is high. The purpose of this investigation is to compare the results of transthoracic ultrasonography for the diagnosis of covid pneumonia to those obtained using conventional methods (clinical characteristics, laboratory tests, and chest computed tomography). Methods and Patients One hundred patients with confirmed cases of COVID-19 pneumonia were recruited from the isolation sections (ward or ICU) at Benha University Hospital between June 2021 and January 2022 for this prospective observational research. The average age of the patients in the study was 53 15 years. There were more men than women among the patients (58%). In the population under study, fever was the most prevalent symptom. The most prevalent result was GGO, and the CT chest score ranged from 3 to 25 with a median of 14. The median LUS score was 16 and the most frequent result was a B line. There was a negative link between chest CT, LUS, and oxygen saturation, and a positive correlation between these variables and inflammatory markers such C-reactive protein, lactate dehydrogenase, and D-dimer. There was a favourable correlation between LUS and chest CT score. When predicting death, a LUS score > 24 had a sensitivity of 95.2% and a specificity of 96.2%, whereas a chest CT cutoff of > 18 had a sensitivity of 100% and a specificity of 87.3%. The LUS score was a strong indicator of mortality risk. Patients with suspected cases of COVID-19 pneumonia may benefit from LUS as a safe and effective diagnostic tool, as shown by CT results. The LUS score was highly associated with both the lab results and the CT severity score, making it a reliable mortality predictor. Coronavirus pneumonia, HRCT severity score, transthoracic ultrasound, ultrasound at the point of treatment.
Pulmonary complications of antiviral drugs (Sofosbuvir and Pulmonary complications of antiviral drugs (Sofosbuvir and Daclatasvir) used in treatment of patients with chronic hepatitis C Daclatasvir) used in treatment of patients with chronic hepatitis C virus virus

Background: Egypt has one of the highest hepatitis C virus (HCV) prevalence rates in the world, which led the government to strive to control it. The national guidelines for chronic HCV treatment had been modified to be interferon-free regimens by giving, the pan-genotypic direct acting antiviral agents (DAAs), sofosbuvir plus daclatasvir with or without ribavirin regimen. The aim of the study was the evaluation of the development of any considerable pulmonary complications among Egyptian patients receiving the combination of sofosbuvir plus daclatasvir for the treatment of chronic HCV infection. Patients and Methods: The study included fifty patients with chronic HCV who were planned to be treated with sofosbuvir plus daclatasvir regimen. They were followed up during the course of the treatment to report and diagnose any developed respiratory symptoms, with two main stations of assessment (pre-and post-treatment), to compare between both outcomes. Results: Nine patients (18%) developed respiratory symptoms during this regimen, in the form of cough (16%), sputum production (6%), dyspnea (6%), fever (6%), and rhinorrhea (4%). Their diagnoses were; acute bronchitis (2 patients), flu-like symptoms (2 patients), cough due to gastro-esophageal-reflux-disease (1 patient), mild airway hyper-responsiveness (1 patient), community-acquired pneumonia (1 patient), community-acquired pneumonia with para-pneumonic effusion (1 patient) and idiopathic pleural effusion (1 patient). They were managed without discontinuation of the regimen. Conclusion: Sofosbuvir plus daclatasvir regimen was generally safe on the respiratory system, and some patients developed manageable non-serious respiratory events during the course of treatment.
Population Characteristics of Channel Catfish in Meeker Reservoir, Oklahoma, a Small Impoundment

: Channel Catfish are a popular sportfish throughout North America and agencies often support put-grow-take fisheries for Channel Catfish in small impoundments. The Oklahoma Department of Wildlife Conservation (ODWC) stocks impoundments throughout Oklahoma with Channel Catfish to provide anglers with catfishing opportunities. Meeker Reservoir (85.8 ha) is a small impoundment located in central Oklahoma that has been historically stocked with Channel Catfish. Uniquely, Meeker Reservoir also has a naturally reproducing population of Blue Catfish that is stunted. Sampling information for Meeker Reservoir is limited and preliminary analysis suggested that Channel Catfish were also stunted. Therefore, our objective was to describe the population characteristics of Channel Catfish in Meeker Reservoir using both 25-mm and 12.5-mm mesh tandem, baited hoop net sets. The Channel Catfish in Meeker Reservoir were stunted, slow growing, dominated by stock size individuals, and had relatively low mortality. Low reservoir productivity, ODWC Channel Catfish stocking rates, and high Channel Catfish and Blue Catfish abundances may be contributing to their slow growth. Additional research should focus on examining the interspecific competition of Blue Catfish and Channel Catfish, potential environmental factors that lead to Channel Catfish recruitment, and angler dynamics of Channel Catfish in small impoundments.
Endoscopic ultrasound-guided drainage and necrosectomy of walled-off pancreatic necrosis using a metal stent with an electrocautery-enhanced delivery system and hydrogen peroxide

Direct endoscopic necrosectomy of walled-off pancreatic necrosis (WOPN) has recently been reported to have comparable success rates to surgery, but with lower morbidity and mortality [1,2]. The procedure is, however, time consuming and requires multiple device exchanges [3], whichmay increase the risk of complications. A novel, dedicated device, the Hot AXIOS (Xlumena Inc., Mountain View, California, USA) (●" Fig.1), has recently become available. This consists of a large-diameter, fully covered self-expanding metal stent (FCSEMS) with antimigration flanges, which is mounted on a 10.8-Fr delivery system with an electrocautery blade at its distal tip. We performed endoscopic ultrasound (EUS)-guideddrainageof aWOPN (median size 17cm, range 10–20cm) in four patients using the Hot AXIOS to directly create a transmural fistula, enter the cavity, and place a 15-mm×10-mm FCSEMS, which was completely deployed under real-time EUS guidance (●" Fig.2). A standard gastroscope was then used to perform balloon dilation of the lumen of the FCSEMS up to 15mm to allow entry into the cavity and perform direct endoscopic necrosectomy. Preliminary data have suggested that irrigation of the necrotic content of areas of WOPN with hydrogen peroxide (H2O2) can facilitate necrosectomy [4,5], so we injected 40– 60mL hydrogen peroxide (3%) into the cavity at the beginning and at the end of each session of direct endoscopic necrosectomy. We then used extraction nets, baskets, and forceful irrigation to clean the necrotic material (●" Video 1). The four patients underwent a median of five endoscopy sessions (range 4–6). A pneumoperitoneum occurred in one patient and was treated conservatively. The FCSEMSs were easily removed in three patients. In the remaining patient, who did not present for follow-up until 138 days after insertion of the FCSEMS, overgrowth of normal mucosa had occurred and a decisionwasmade to leave the stent permanently in place. No recurrence of WOPN has been observed after a mean follow-up of 8.5 months (range 5–10 months).
Implications of Using the BRIEF-Preschool With School-Age Children With Down Syndrome.

This study evaluated the appropriateness of scoring the Behavior Rating Inventory of Executive Function-Preschool (BRIEF-P) using age-equivalent scores generated from multiple measures of cognition and language among school-age children with Down syndrome (DS). Subscale T scores for 95 children with DS were contrasted using standard scoring on the Behavior Rating Inventory of Executive Function-Second edition (BRIEF-2; based on chronological age) to alternate scoring using the BRIEF-P (based on age-equivalent) for patterns of subscale intercorrelations, differences in mean scores, and agreement on findings from clinical cut-off scores. Results with children with DS suggested using (1) the BRIEF-P for children ages 2-5 years old, (2) the BRIEF-2 with chronological-age scoring or the BRIEF-P with age-equivalent scoring (with some caveats) for research on children ages 5-10 years old, and (3) the BRIEF-2 for children ages 11 and older.
Atrial Fibrillation Post Coronary Artery Bypass Grafting Surgery Atrial Fibrillation Post Coronary Artery Bypass Grafting Surgery Incidence and Risk factors Incidence and Risk factors

Background: Atrial fibrillation is a common complication following cardiac surgery, especially coronary artery bypass grafting. Although this condition mostly benign but it can increase mortality and morbidity postoperative and leading to longer ICU stay and increase the costs. Aim of the study: to investigate and analyse the atrial fibrillation incidence and risk factors in patient undergoing CABG in addition to its effect on intensive care unit and postoperative hospital stay. Patients and Methods: Our study was retrospective non-randomized. Between January 2018 and January 2020, 50 patients were recruited from a total of 225 patients who underwent coronary artery bypass graft surgery at Al-Azhar University Hospitals. In these 50 cases, we studied their risk factors that were possibly connected to the development of atrial fibrillation post CABG surgeries. Results: In our study, the rate of POAF was 22.22 percent, with 50 patients out of 225 underwent isolated CABG operations over the course of two years. Our findings show that old age, a history of hypertension, smoking, low ejection fraction, a dilated left atrium, longer bypass time, early ischemic changes in ECG and low potassium level are all predictors of atrial fibrillation after Coronary Artery Bypass Grafting. Conclusion: Atrial fibrillation is the most frequently occurring arrhythmic complication post cardiac surgery. Around 10%–60% of patients undergoing coronary artery bypass graft and valvular surgery experience new-onset atrial fibrillation. Although it is a benign complication, it may contribute to mortality, morbidity, and prolongs the ICU stay, and elevates the hospitalization costs.
Therapy dogs effectively reduce stress in college preparatory students

comfort from their pet than cat owners. Another study surveyed students on their interest in pet therapy programs; 96% of the college freshmen interviewed expressed great interest in the possibility (15). Thus, the effectiveness of trained therapy dogs in improving students’ mental health is under investigation. A therapy dog and close human friend were both tested as companions in a standard stress test to determine which was more effective in lowering stress levels. The presence of the therapy dog reduced levels of the stress hormone cortisol in saliva more effectively than the presence of a close human friend (15). Interaction with a therapy dog also helped university students
Robust Multimodal and Multi-Object Tracking for Autonomous Driving Applications

In this work, we present a method for Multi-Object Tracking (MOT) that uses unsynchronized multimodal detections from a configurable set of sensors such as cameras, radars and lidars. All the information is processed from the sensors with modality-specific detectors and then combined in the MOT module that incorporates a Kalman filter and tracklet management logic. To be able to deploy our system in real-world driving applications, we handle localization errors, misclassifications and partial bounding-box detections from the object detector in the MOT module. We show promising results and compare them with respect to competing approaches in two challenging real-world scenarios, including a traffic jam chauffeur as well as a traffic monitoring application on highways.