Miracle-dz/UniFAR-FTUs huggingface dataset:
Full Title: Development and validation of a potential salivary biomarker panel for Oral Squamous Cell Carcinoma.

Purpose Oral Squamous Cell Carcinoma (OSCC) is one of the most prevalent cancers in the world with maximum number of cases reported from India. Poor survival rate associated with OSCC can be attributed to non-availability of a biomarker, as one of the major reasons, leading to late presentation. Identification of an early diagnostic biomarker, which can also be used as a screening tool, will be helpful in reducing the disease morbidity and mortality. Experimental Design: In this article we report Parallel Reaction Monitoring (PRM) based validation of 12 candidate proteins, identified initially by TMT tag based relative quantification of salivary proteins on LC-MS, in the saliva of Oral Squamous Cell Carcinoma (OSCC) cases (N=50) and healthy controls (N=49), AZGP1, AHSG, KRT6C, S100A7, S100A9, KLK1, BPIFB2, IGLL5, CORO1A, LACRT, LCN2 and PSAP. Heavy isotope labelled reference peptides were used to produce calibration curve and absolute quantification of proteins and resulting data was analyzed statistically using R. We report a potential biomarker panel consisting of proteins AZGP1, AHSG and KRT6C for early diagnosis of OSCC.
Case Report ANCA-associated vasculitis complicated by haemoperitoneum

We present a case of myeloperoxidase-antineutrophil cytoplasmic antibody (MPO-ANCA)-associated vasculitis with the rare complication of haemoperitoneum due to mesenteric vessel involvement. Initial investigations demonstrat-ed typical renal features including haematoproteinuria and a focal segmental necrotising glomerulonephritis. The patient then developed haemoperitoneum and required an emergency hemicolectomy. Subsequent histology revealed ileo-colic arteritis with aneurysm formation and rupture. A sustained remission was achieved with corticosteroids and mycophenolate mofetil followed by azathioprine. This case demonstrates the need for a high degree of vigilance in pa-tients with ANCA-associated vasculitis who develop abdominal symptoms.
ANALYSIS OF RISK FACTORS OF HYPERTENSION AMONG ADULT POPULATION OF PAKISTAN

: Introduction: Hypertension has been recognized as a global health concern for developing countries and is scarcely described in many of these countries. In Pakistan, few population-based surveys evaluated the prevalence of hypertension and there is no current nationally representative study. Aims and objectives: The basic aim of the study is to analyze the prevalence of hypertension and high blood pressure among local population of Pakistan. Methodology of the study: This cross sectional study was done at Wazirabad Institute of Cardiology Wazirabad, Gujranwala during January 2019 to July 2019. The sample size for the present study was calculated by taking most probable prevalence of hypertension as 50% and permissible error as 5% with 95% confidence interval. Fixing the permissible error as 50%, the minimum sample size was calculated as n = 100. Results: Regarding the self or family history of any chronic disease; 50 (10.3%), and 16 (3.3%) of the total study participants were known hypertensive, and diabetes mellitus (DM) patients respectively, while 82 (16.8%) and 64 (13.1%) have family history of hypertension and DM respectively. There are number of factors which influence on blood pressure levels. Age, cholesterol, BMI and diet are the main factors which directly effect on blood pressure levels. Conclusion: It is concluded that increasing age is proved to be an independent
4 The Ca 2+ requirement for the S 1 to S 2 transition of the oxygen-evolving complex

The functional role of the Ca 2+ ion in the oxygen-evolving complex of photosystem II (PSII) is not yet clear. Current models explain why the redox cycle of the complex would be interrupted after the S 3 state without Ca 2+ , but the literature shows that it is interrupted after the S 2 state. Re-interpretation of the literature on methods of Ca 2+ depletion (Chapter 2 / Miqyass et al 2007 Photosynth Res 92: 275-287) led us to conclude that not only the oxidation of S 2 to S 3 but also the oxidation of S 1 to S 2 requires Ca 2+ . Here we confirm this interpretation. Ca 2+ depletion of PSII membranes by high ionic strength was studied by measuring flash-induced S-state transitions in UV absorbance. Using KCl instead of NaCl, we found that a 30 minute incubation in the dark leaves PSII in an inactive S 1 state, where a flash caused oxidation of the secondary electron donor Y Z only. However, a 30 min exposure to room light in the presence of KCl and a Ca 2+ chelator produced the inactive stable S 2 state, in which Y Z oxidation was also largely inhibited. In the absence of Ca 2+ , Y Z • can still oxidize S 1 to S 2 but the flash yield is negligible, which indicates an essential functional role of Ca 2+ in the S 1 to S 2 transition.
Radiographic Quantitative Assessment of Caudal Proximal Tibial Angulation in 100 Dogs with Cranial Cruciate Ligament Rupture

Objective To evaluate inter- and intraobserver variability in the measurement of distal tibial axis/proximal tibial axis angle (DPA) from lateral radiographs of canine tibia in dogs with cranial cruciate ligament rupture (CCLR). Study Design Retrospective clinical study. Animals Dogs (n=100) with cranial cruciate ligament rupture. Methods Medical records of dogs diagnosed with CCLR were reviewed. In addition to signalment and TPA measurements, measured DPA (mDPA) was calculated for each lateral view of the tibia in each animal, twice, by 3 blinded observers. Subjective scoring of DPA (sDPA) was also recorded, twice, by 3 additional blinded observers from lateral views of the proximal half of the tibia in each dog. Inter- and intraobserver variability was measured by intraclass correlation coefficient (ICC) for each measurement. Correlation between mDPA and sDPA was also determined. Results Median tibial plateau angle (TPA) of the subject population was 27.9° (range 18.8–41.3°; IQR: 25.5–30.75°). Mean ± SD mDPA was 6.50 ± 2.81° (confidence intervals [CI]: 5.94–7.06°; range 0–13.33°). There was no correlation between age and weight of dogs and the mDPA (P=.58 and .12). There was a moderate correlation between mDPA and TPA (r2=0.49, P<.0001). There was a moderate correlation between sDPA and mDPA (r2=0.27, P<.0001). Good inter- and intraobserver agreement was found in the measurement of mDPA. Conclusion mDPA is a reproducible measurement of caudal angulation of proximal tibia. Furthermore, mDPA of dogs with cranial cruciate ligament disease in this report are in concordance with previous reports.
Topic Linkages between Papers and Patents

The papers and patents are usually considered as the indicators of basic science studies and technologies, respectively. Previous linkage research between papers and patents mainly focus on the analysis of non-patent literature cited by patent from the viewpoint of citation analysis. Thus, one will miss many valuable scientiﬁc papers that are not cited by patents until now. This paper proposes a simple procedure for constructing topic linkages between papers and patents by analyzing these two kinds of information resources simultaneously. Experimental results on new energy vehicles indicate that our approach is feasible and eﬃcient.
2018 PD Behaviors of Monoester Insulating Oil under Different Moisture

a.rajab@eng.unand. ac.id Abstract One of the problems encounters in implementing vegetable oils (natural esters) as a transformer insulating oil is their viscosity which is high. To address this problem, monoester derived from vegetable oil was introduced. This paper deals with partial discharge (PD) behaviors of dry and moist samples of a monoester type insulating oil, palm fatty acid ester (PFAE), under AC high voltage utilizing a needle plane electrode configuration. Variations of average PD charge and PD number against the variation of voltage application, as well as their polarity discrimination under both dry and moist sample conditions are analyzed. PD pulses phase distributions of both dry and moist sample oils are elaborated. Finally, a mechanism of the water molecules effect on PD behavior is proposed based on experimental results and shown
Towards Fair Multi-Stakeholder Recommender Systems

Since recommender systems (“RSs”) are used in multiple domains and applications, issues of possible biases and discrimination have become paramount and present a technical challenge. Indeed, fairness in and for RSs is specific as it does not only concern protected attributes but also encompasses notions of user representativeness and item diversity. In short, RSs require multi-stakeholder fairness. However, RSs are generally built on large (and possibly very sparse) datasets, thus precluding the use of very complex debiasing techniques. Our approach introduces a fairness functional that minimises the loss disparity across groups and avoids a post-processing step. This enables us to adapt most algorithms underlying recommender systems, such as factorisation machine and its many generalisations and debias them. We present an example of such a functional and show that its properties are ideally suited to the case of multi-stakeholder fair RS. Finally, we demonstrate that our approach works well in practice on benchmark datasets and that partial debiasing is essential, as full debiasing may lead to poor generalisation.
On the benefits of using Hidden Markov Models to predict emotions

The availability of low-cost wireless physiological sensors has allowed the use of emotion recognition technologies in various applications. In this work, we describe a technique to predict emotional states in Russell’s two-dimensional emotion space (valence and arousal), using electroencephalography (EEG), electrocardiography (ECG), and electromyography (EMG) signals. For each of the two dimensions, the proposed method uses a classification scheme based on two Hidden Markov Models (HMMs), with the first one trained using positive samples, and the second one using negative samples. The class of new unseen samples is then decided based on which model returns the highest score. The proposed approach was validated on a recently published dataset that contained physiological signals recordings (EEG, ECG, EMG) acquired during a human-horse interaction experiment. The experimental results demonstrate that this approach achieves a better performance than the published baseline methods, achieving an F1-score of 0.940 for valence and 0.783 for arousal, an improvement of more than + 0.12 in both cases.
What Are Filter Bubbles Really? A Review of the Conceptual and Empirical Work

The original filter bubble thesis states that the use of personalization algorithms results in a unique universe of information for each of us, with far-reaching individual and societal consequences. The ambiguity of the original thesis has prompted both a conceptual debate regarding its definition and has forced empirical researchers to consider their own interpretations. This has led to contrasting empirical results and minimal generalizability across studies. To reliably answer the question of whether filter bubbles exists, on what platforms, and what caused them, we need a systematically and empirically verifiable definition of the filter bubble that can be used to develop rigorous tests for the existence and strength of a filter bubble. In this paper, we propose an operationalized definition of the (technological) filter bubble and interpret previous empirical work in light of this new definition.
Reduction in Glomerular and Renal Tubular Damage in Kidneys of Diabetic Rats Supplemented with Alpha-Lipoic Acid

Abstract Chronic hyperglycemia caused by diabetes results in systemic damage to the body, and the kidney ends up being the target of tissue damage. The use of antioxidants such as alpha-lipoic acid (ALA) has been shown to improve clinical and biochemical parameters in diabetic patients as they help in the prevention of oxidative stress. The present study aimed to undertake a comparative evaluation of the renal morphology of normal and diabetes-induced Wistar rats supplemented with ALA. The experiment had 4 experimental groups (n=7): a control group and a diabetic group that were fed commercial food; an alpha-lipoic group and an alpha-lipoic diabetic group that received the ALA supplement. Diabetes was induced with a single intraperitoneal injection of alloxane monohydrate administered after fasting. After 60 days of the experiment, the kidneys were excised to study the histomorphometric and stereological parameters of the glomeruli and renal tubules and the immunohistochemical parameters with a podocyte count. In the evaluation, the ALA promoted improvement in all of the relevant parameters of the glomerular areas and attenuation of tubular lesions of diabetic animals (p<0.001). Supplementation with ALA also showed beneficial effects in diabetic animals, such as reducing hyperglycemia and the damage promoted by oxidative stress alongside promoting a protective effect on the renal parenchyma. The reduction of glomerular and tubular damage delayed the advance of diabetic nephropathy and its complications, preventing renal failure in diabetic groups.
Petrogenesis of Miocene igneous rocks in the Tafresh area (central Urumieh‐Dokhtar magmatic arc, Iran): Insights into mantle sources and geodynamic processes

Cenozoic tectono‐magmatism in Iran is widely considered to be related to subduction of the Neo‐Tethys Ocean. We employed whole‐rock and mineral geochemistry and isotopic data of intrusive rocks from Tafresh, central Urumieh‐Dokhtar magmatic arc, to evaluate the role of the mantle in magmatism, to assess the timing of emplacement, and to interpret the tectonic setting. Rock compositions range from gabbro or gabbro‐diorite (plagioclase + pyroxene ± olivine), to diorite (plagioclase + amphibole ± pyroxene), to granodiorite (quartz + plagioclase + K‐feldspar + amphibole + biotite), exhibiting high‐alumina calc‐alkaline affinity. Major oxide and trace element variations vary systematically from less to more evolved rocks suggesting a major role for fractional crystallization processes. Zircon LA‐ICP‐MS U–Pb ages of major rock types are in the range of 24–19 Ma, whereas those of gabbroic dikes are ~17.5 Ma. ԐNd values range between −1.8 and 3.7, and (87Sr/86Sr)i is narrowly restricted to 0.705–0.706, suggesting a common mantle source. The enrichment in light rare earth element (REE) enrichment and flat heavy REE patterns couple depletion of Nb–Ta–Ti indicate that subducting oceanic crust had interacted with the overlying mantle wedge. High‐alumina, mid‐Mg# Tafresh plutonic rocks formed from hydrous melts from which Ca‐pyroxene and magnetite crystallized earlier than plagioclase, whereas late‐crystallizing zircon nucleated while magma traversed through lithospheric mantle and Cadomian crust. Modelling of isotope and incompatible‐element patterns suggests the contribution of no more than ~5% molten sediment or other crustal components in Tafresh magma, at a developmental stage before most plagioclase and amphibole had crystallized. The Miocene Tafresh plutons originated during the final stages of subduction, before the collision between the Arabian and Eurasian plates.
Trajectories of Self-Esteem Development for Adolescence Based on China Family Panel Studies: A Piecewise Growth Mixture Model Analysis

Self-esteem has always been a hot research object in the field of adolescent mental health. But in longitudinal research, using a single slope to describe the trajectory of adolescent self-esteem is unrealistic. The piecewise growth mixture model (PGMM) was used to fit the data in this study. Selecting from China Family Panel Studies database, a total of 1,759 individuals were selected and their self-esteem (RSES) scores over the years were used as the tracking index. Based on the characteristics of the development trajectories of three latent classes, class 1 was referred to as “stable low level group,” class 2 was named “rapidly rising group,” and class 3 was referred to as “rapidly decrease group. ” And there were two stages in the development process of self-esteem in the adolescent group. The slope of the stable low level group showed a significant downward trend in the first stage and a significant upward trend in the second stage, with a relatively flat development trajectory and relatively low self-esteem on the whole. The slope of the rapidly rising group showed an insignificant upward trend in the first stage and a significant rapid upward trend in the second stage. The rapidly decrease group showed a significant and rapid downward trend in the first stage and a significant and rapid upward trend in the second stage. In the development of self-esteem in adolescence, there were three latent classes in which the characteristics of development trajectories were different. Age of 14 is the turning point between the two stages of development.
Subjective and Objective Measures of Activity in Depressed and Non-depressed Individuals in Everyday Life

Reduced physical activity is considered a key feature of major depressive disorder (MDD). However, research directly comparing non-depressed controls and patients yielded mixed findings. In contrast to most previous research, this study compared objective as well as subjective activity levels of individuals with MDD with non-depressed controls and used an ambulatory assessment method. Moreover, we investigated whether objective and subjective measures of activity could predict mood. On two consecutive days, physical activity of 35 MDD patients and 36 non-depressed control participants were assessed objectively using an accelerometer and subjectively with hourly ecological momentary assessments. During the same assessment, participants mood was monitored. No significant differences between MDD patients and control participants in objective and most of the subjective activity measures were observed. We found significant associations between objective and subjective measures of activity in non-depressed as well as in MDD patients. Objective but not subjective measures of activity predicted subsequent mood. Our results support the notion that the association between MDD and activity level is complex and depends on moderating factors.
BIM application and collaboration in construction projects: a perspective of the Chinese construction market

Abstract Although building information modelling (BIM) is endowed with the potential for collaboration, the nature of the relationship between BIM application and collaboration has not been well-elaborated. This research classifies collaboration into the two dimensions of cooperation and coordination and empirically tests a model to understand not only the effect of BIM application on collaboration in construction projects but also the moderating effects of fairness perception and contract specificity. Using 296 samples from the Chinese construction industry, this research reveals the existence of a positive relationship between BIM application and collaboration. In addition, fairness perception weakens the relationship between BIM application and both collaboration dimensions of cooperation and coordination, while contract specificity strengthens the effect of BIM application on the coordination dimension only. These findings offer new insights through a nuanced understanding of the nature of the relationship between BIM application and collaboration, providing useful guidance for BIM application in the construction industry.
Student's Conception about Friction Force Direction in Physics Education Sebelas Maret University

The student's conception of friction force direction on objects is different. Student’s conceptions are important to improve the next learning process. The aim to the research was to know student’s conception about friction force direction. This research was a qualitative descriptive. Samples consisted of 33 students from Physics Education UNS semester 1 who have not obtained the material friction in the lecture. Data collected through test and intervie. Data were analyzed by reduction, presentation, conclusion and verification. Based on the result of student conception showed the average of 82,82% student can describe the direction of friction force on objects with translational motion, 18,18% student can describe the direction of friction force on objects with translational and rotation motion inclane and all students can not describe the direction of friction force on bicycle wheels.
Diet and Genetic Risk Factors of Colorectal Cancer in Palestine: A Case-Control Study

Abstract To add evidence to the limited data available on colorectal cancer (CRC) from Palestine, we examine the risk factors associated with CRC using a matched hospital-based case-control study. A structured questionnaire was used to collect data from 105 cases and 105 controls. A multivariable conditional regression model was used to adjust for the association between study factors and CRC risk. In the model, compared with controls, cases from villages were significantly less likely to have CRC (Adjusted Odds Ratio, AOR = 0.194); taking aspirin lowered the likelihood of CRC by 24%; and having a multiple birth sibling by 33%. Also, the likelihood of CRC was lowered significantly by consuming five servings of fruits/vegetables per week or more (5–6 servings: AOR = 0.21, 7–8 servings per week: AOR = 0.04). However, cases had a significantly higher likelihood of CRC if they consumed 2–4 servings of grilled red meat per week (AOR = 4.25); smoked (AOR = 4.38); had a sedentary lifestyle (AOR = 2.53); reported parental consanguinity (AOR = 3.88); or had a family history of cancer (AOR = 6.39). Our results confirmed the association between CRC and red meat intake and smoking, and proved that parental consanguinity and family history of cancer are also risk factors for CRC.
“The Statistical Analysis of Compositional Data” by John Aitchison (1986): A Bibliometric Overview

This paper presents a complete bibliometric analysis of Aitchison’s 1986 seminal book “The Statistical Analysis of Compositional Data. ” We have set three objectives. The first is to analyze the academic structure of Aitchison’s 1986 book. Results reveals that although the work has received citations uninterruptedly since its publication, the number of these has increased very significantly over the past 4 years. This is due to the significant increase in the number of publications on the theme of “Compositional Data Analysis” in fields related to “geoscience” over the last few years. The second objective is to determine which main journals Aitchison’s book has been cited in. The results highlight that the main journals are indexed under the following WoS category: “Geosciences, Multidisciplinary” and “Ecology. ” Of these, “Mathematical Geosciences” and “Computers, Geosciences” stand out. The third objective is to determine the main topics analyzed in the principal papers published by authors citing Aitchison’s book. Our results show that the keywords in the main papers to have cited Aitchison’s 1986 book originate from the geoscience field, since many of them are related to concepts directly linked to this field and refer to terms related to “biodiversity,” “geodiversity,” “geoheritage,” and “georesources. ” Lastly, the analysis shows how the CoDA methodology is now in a phase of exponential growth, expanding to other fields. This implies that geoscience is becoming consolidated in the scientific literature as one of the branches of modern science that has given rise to a new mathematical theory of great impact.