Miracle-dz/UniFAR-FTUs huggingface dataset:
Auramine O UV Photocatalytic Degradation on TiO2 Nanoparticles in a Heterogeneous Aqueous Solution

Amongst the environmental issues throughout the world, organic synthetic dyes continue to be one of the most important subjects in wastewater remediation. In this paper, the photocatalytic degradation of the dimethylmethane fluorescent dye, Auramine O (AO), was investigated in a heterogeneous aqueous solution with 100 nm anatase TiO2 nanoparticles (NPs) under 365 nm light irradiation. The effect of irradiation time was systematically studied, and photolysis and adsorption of AO on TiO2 NPs were also evaluated using the same experimental conditions. The kinetics of AO photocatalytic degradation were pseudo-first order, according to the Langmuir–Hinshelwood model, with a rate constant of 0.048 ± 0.002 min−1. A maximum photocatalytic efficiency, as high as 96.2 ± 0.9%, was achieved from a colloidal mixture of 20 mL (17.78 μmol L−3) AO solution in the presence of 5 mg of TiO2 NPs. The efficiency of AO photocatalysis decreased nonlinearly with the initial concentration and catalyst dosage. Based on the effect of temperature, the activation energy of AO photocatalytic degradation was estimated to be 4.63 kJ mol−1. The effect of pH, additional scavengers, and H2O2 on the photocatalytic degradation of AO was assessed. No photocatalytic degradation products of AO were observed using UV–visible and Fourier transform infrared spectroscopy, confirming that the final products are volatile small molecules.
Embedding of $C_q$ and $R_q$ into noncommutative $L_p$-spaces, $1\le p

We prove that a quotient of subspace of $C_p\oplus_pR_p$ ($1\le p<2$) embeds completely isomorphically into a noncommutative $L_p$-space, where $C_p$ and $R_p$ are respectively the $p$-column and $p$-row Hilbertian operator spaces. We also represent $C_q$ and $R_q$ ($p<q\le2$) as quotients of subspaces of $C_p\oplus_pR_p$. Consequently, $C_q$ and $R_q$ embed completely isomorphically into a noncommutative $L_p(M)$. We further show that the underlying von Neumann algebra $M$ cannot be semifinite.
Safety and Efficacy of Allogeneic Natural Killer Cells in Combination with Pembrolizumab in Patients with Chemotherapy-Refractory Biliary Tract Cancer: A Multicenter Open-Label Phase 1/2a Trial

Simple Summary Since there is no effective subsequent-line therapy for patients with cisplatin/gemcitabine-refractory advanced biliary tract cancer, there is an urgent need for new treatment options. This phase 1 and 2a study is the first clinical trial reporting the safety and the efficacy of allogeneic NK cells (“SMT-NK”) in combination with pembrolizumab in patients with chemotherapy-refractory advanced biliary tract cancer. We found that the SMT-NK can be safely administered with pembrolizumab to patients with the chemotherapy-refractory advanced biliary tract cancer, and the combinational therapy of SMT-NK and pembrolizumab showed improved efficacy outcome compared to recent trials using pembrolizumab alone. This study provides evidence for a new possible treatment option for advanced biliary tract cancer patients. Abstract Background and Aim: This study investigated the administration of combination therapy, allogeneic natural killer (NK) cells and pembrolizumab in the treatment of advanced biliary tract cancer to determine the safety and tolerability (phase 1) and the efficacy and safety (phase 2a). Methods: Forty patients (phase 1, n = 6; phase 2a, n = 34) were enrolled between December 2019 and June 2021. The patients received highly activated allogeneic NK cells (“SMT-NK”) on weeks 1 and 2 and pembrolizumab on week 1. This 3-week schedule (one cycle) was repeated until confirmed disease progression, intolerable adverse events (AEs), patient withdrawal, or finishing the maximum treatment schedule. The tumor response was evaluated after every three cycles. Results: In phase 1, four patients (66.7%) experienced seven AEs, but no severe AE was observed. In phase 2a, 126 AEs occurred in 29 patients (85.3%). Severe AEs (≥grade 3) were reported in 16 patients (47.1%). The overall response rate (ORR) was 17.4% in the full analysis set and 50.0% in the per-protocol set. Conclusions: SMT-NKs plus pembrolizumab resulted in no severe AEs directly related to the drug combination. The combination therapy also exerted antitumor activity with improved efficacy compared to the recent monotherapy with pembrolizumab in patients with advanced biliary tract cancer.
Metal Abundances at z < 1.5: Fresh Clues to the Chemical Enrichment History of Damped Lyα Systems

We explore the redshift evolution of the metal content of damped Lyα systems (DLAs) with new observations of four absorbers at z<1.5; together with other recently published data, there is now a sample of 10 systems at intermediate redshifts for which the abundance of Zn has been measured. The main conclusion is that the column density-weighted mean metallicity, [⟨Zn/H⟩]=-1.03±0.23 (on a logarithmic scale), is not significantly higher at z<1.5 than at earlier epochs, despite the fact that the comoving star formation rate density of the universe was near its maximum value at this redshift. Gas of high column density and low metallicity dominates the statistics of present samples of DLAs at all redshifts. For three of the four DLAs, our observations include absorption lines of Si, Mn, Cr, Fe, and Ni, as well as Zn. We argue that the relative abundances of these elements are consistent with a moderate degree of dust depletion that, once accounted for, leaves no room for the enhancement of the α elements over iron seen in metal-poor stars in the Milky Way. This is contrary to previous assertions that DLAs have been enriched solely by Type II supernovae, but it can be understood if the rate of star formation in the systems studied proceeded more slowly than in the early history of our Galaxy. These results add to a growing body of data pointing to the conclusion that known DLAs do not trace the galaxy population responsible for the bulk of star formation. Possible reasons are that sight lines through metal-rich gas are systematically underrepresented, because the background QSOs are reddened, and that the most actively star-forming galaxies are also the most compact, presenting too small a cross-section to have been probed yet with the limited statistics of current samples.
Determination of Optimum Conditions for Ergosterol Production by Saccharomyces cerevisiae

Ergosterol is an important provitamin in the present-day of industrial biotechnology. Seven yeast strains were obtained from the market of Basrah city and subjected to screening for their ergosterol production ability using liquid-state fermentation, the cultural conditions, and nutritional requirements for optimal production of ergosterol by Saccharomyces cerevisiae under laboratory conditions were determined. Y.6 is the best isolate of the yeast that produced ergosterol. It was identified as S. cerevisiae, with a similarity rate of 97% by using the Vitek2 device, this S. cerevisiae (Y.6) was further subjected to optimization conditions. The results showed that the best medium for production was yeast extract peptone dextrose broth. The effect of two cheaper carbon sources, molasses and date juice were investigated. Maximum ergosterol (0.55% ) was produced using a medium containing date juice, with a replacement ratio of 75%, an incubation time of 72 hours, pH 5, at a temperature of 30 °C, and an inoculation volume of 4 ml. The percentage of ergosterol was (0.47, 0.55, 0.74, 0.66, 0.68 and 0.78 %), respectively.
Caracterización del arbolado urbano del centro de Hualahuises, Nuevo León

Los árboles constituyen un recurso importante en las zonas urbanas debido a los servicios ambientales que brindan. El objetivo de este estudio fue evaluar la composición florística, estructura y diversidad del arbolado urbano del centro de Hualahuises, Nuevo León. Se evaluó el arbolado urbano de los espacios públicos del centro de Hualahuises, abarcando las plazas públicas y aceras. A cada árbol se le midieron su altura total, el diámetro normal y diámetro de copa. Para cada especie se determinó su abundancia, su cobertura, y su frecuencia, para obtener su Índice de Valor de Importancia. También se determinó la riqueza de especies mediante el índice de Margalef, el índice de diversidad de Shannon, y el número de especies efectivas. Se registraron 38 especies de plantas vasculares distribuidas en 35 géneros y 22 familias. El 63.20 % (25 especies) son introducidas y el 36.8 % (21 especies) son nativas. La familia más representativa fue Fabaceae con cuatro especies. Los análisis de clases diamétricas y de altura indican una mayor proporción de individuos con diámetros bajos (d1.30<5 cm) y alturas intermedias (h>3 m y <6 m). La comunidad vegetal presenta valores intermedios-altos de riqueza y altos de diversidad de especies comparado con otras áreas verdes urbanas del noreste de México. Más de la mitad de las especies (63 %) son introducidas, entre las cuales Fraxinus americana y Thuja occidentalis sobresalen por su Índice de Valor de Importancia. La especie nativa con mayor valor de importancia fue Quercus virginiana.
Interfacial dynamics in 3D binary fluid demixing: animation studies*

The late-stage phase ordering, in three dimensions, of fully symmetric binary fluid mixtures is studied via a lattice Boltzmann method. We present time-resolved maps of the fluid velocity fields and also animated visualizations of the interfacial motion. These show distinct features corresponding to regimes where viscous, crossover and inertial hydrodynamic scaling have previously been identified. Specifically, while the interface is overdamped in the viscous regime, it exhibits recoil after topological reconnection at intermediate and higher inertia; and in our most inertial runs the interface shows extensive underdamped capillary disturbances not attributable to topological reconnection events. The advantages and practicality of presenting such dynamical data in fully animated form are demonstrated and briefly discussed. This paper's animations are available from the Multimedia Enhancements page as individual files and also packed into archives (two formats).
Clinicopathological characteristics predicting advanced stage and surgical margin invasion of oral squamous cell carcinoma: A single-center study on 10 years of cancer registry data

The incidence profile of oral squamous cell carcinoma (OSCC) has not previously been comprehensively reported in Indonesia. The present study aimed to identify clinicopathological characteristics of patients with OSCC according to sex and age, to analyze histological differentiation patterns specific to tumor subsites, to highlight the role of lymphovascular invasion (LVI) in metastasis, and to develop a model to predict advanced stage and margin invasion. A retrospective cross-sectional study was performed using 581 medical records and pathological specimens from cancer registry data in the Dr Cipto Mangunkusumo Hospital (Jakarta, Indonesia), between January 2011 and December 2020. Clinicopathological characteristics were analyzed using parametric and non-parametric tests. Multivariate logistic regression analyses were performed for eligible parameters, identified using bivariate analysis, to predict advanced stage and margin invasion. Calibration of the prediction model was evaluated using the Hosmer-Lemeshow test, its discrimination value assessed using the receiver operating characteristic and area under the receiver operating characteristic curve (AUC). Sex-specific patterns in tumor subsites and differences in clinical staging according to age were demonstrated in the patients with OSCC. The proportion of well-differentiated cases was significantly higher in most tumor subsites, except in the buccal mucosa (more moderately differentiated cases) and floor of the mouth (well and moderately differentiated cases being equal). LVI was significantly associated with nodal metastasis but not distant metastasis. Multivariate analysis demonstrated that age ≤45 years [odds ratio (OR), 2.26] and LVI (OR, 8.42) predicted patients having advanced-stage OSCC among general populations (AUC, 0.773); however, LVI (OR, 8.28) was the sole predictor of advanced stage amongst young patients (AUC, 0.737). Margin invasion was predicted solely by tumor subsite, including mouth not otherwise specified (OR, 3.04) and palate (OR, 6.13), in the general population (AUC, 0.711). Furthermore, margin invasion was predicted by the palate subsite (OR, 38.77) and LVI (OR, 11.61) in young patients (AUC, 0.762). Investigating young patients thoroughly when finding SCC in the mouth and palate, and assessing LVI, especially among young patients, is critical to prevent advanced staging and margin invasion.
The Impact of Technological and Infrastructural Facilities on Student’s Learning: A Change Management Perspective

Purpose: Change management is a systematic and methodical approach to dealing with organizational transitions and transformations with the ultimate goal of a prospective future. Technological and Infrastructural upgrades in any organization have been linked with strategic transformational change. This paper sheds light on the impact of technological and infrastructural facilities on students’ learning. Design/Methodology/Approach: By following a quantitative research approach, data was collected through a survey questionnaire from 437 students enrolled in Public Sector Universities of Sindh province. Findings: The findings revealed that Technological and Infrastructural facilities in Higher Education Institutes can positively influence the learning experience of students. The subdivision of technological facilities into basic, moderate, and advance level offers deeper insight pertinent to students' perceptions of technological literacy and its interaction with their learning experience in this digital era. Moreover, infrastructural facilities are linked with a conducive environment that ultimately could enrich students’ learning experience. This study's findings call for notable measures for the provision of adequate facilities to students across public sector higher education institutes. Implications/Originality/Value: So it is concluded that technological and infrastructural facilities in Public Sector Higher Education Institutes have positive impact on the Learning experience of Students.
Effect of different levels of segmental trunk stability training on sitting and upper limbs functions in children with bilateral spastic cerebral palsy

Background: Children with bilateral spastic cerebral palsy (BSCP) have insufficient trunk control and upper limbs (ULs) dysfunction. Purpose: to investigate the effect of segmental trunk stability training at different levels on sitting and ULs functions in children with BSCP. Subjects & Methods: Thirty-nine children with BSCP, with ages ranged from 2 to 4 years, , their spasticity grade ranged from 1 to 1+ according to the Modified Ashworth Scale, their motor function was at level IV according to the Gross Motor Function Classification System – Expanded and Revised, their self-initiated ability to handle objects in daily activities with their hands was at level V according to the Mini-Manual Ability Classification System, all children’s level of segmental trunk control score ranged from 3 to 5 according to the Segmental Assessment of Trunk Control were assigned randomly to 3 groups of equal numbers, 13 children for each group. Group (A) received a specially designed physical therapy (PT) program while wearing segmental trunk support from a level just below the child’s inferior angle of the scapula to the level of his/her pelvis.
Comparison of the effects of clinical observation and protocol-based weaning on antioxidant stress factors

ABSTRACT BACKGROUND: We aimed to compare the effects of observation of the physician (POB) or by adhering to the protocol-based (PB) weaning methods on total antioxidant capacity (TAC) and total oxidative stress (TOS) levels and weaning success levels. METHODS: Our study was conducted on patients admitted from the emergency department between January 2015 and January 2018 in the intensive care unit of our hospital. During the spontaneous breathing trial (SBT), when one of the criteria specified in developed, SBT was terminated and the previous mechanical ventilator parameters were returned. The patient was planned to be taken to SBT again the next morning. If the SBT was successful, extubation was decided. The extubation decision based on physician observation was made according to the patient’s state of consciousness and adequate chest expansion during the daily visit. RESULTS: The decrease in TAC average value before and after extubation was found to be significant in the POB group patients (p=0.001). The decrease in the average TAC value of the PB group patients before and after extubation was found to be significant (p=0.03). CONCLUSION: In our study, TAC values were found to be higher in the PB group than in the POB group, and in addition, the reintubation rate was found to be lower. We think that the management of weaning as a PB may contribute to maintaining the balance between TAC and TOS and reduce the rate of reintubation.
Characterization of Carbapenemase-Producing Klebsiella pneumoniae Isolates from Two Romanian Hospitals Co-Presenting Resistance and Heteroresistance to Colistin

Klebsiella pneumoniae is a notorious human pathogen involved in healthcare-associated infections. The worldwide expansion of infections induced by colistin-resistant and carbapenemase-producing Enterobacterales (CPE) isolates has been increasingly reported. This study aims to analyze the phenotypic and molecular profiles of 10 colistin-resistant (CR) isolates and 2 pairs of colistin-heteroresistant (ChR) (parental and the corresponding resistant mutants) isolates of K. pneumoniae CPE sourced from two hospitals. The phenotypes of strains in the selected collection had been previously characterized. Antimicrobial susceptibility testing was performed using a Vitek 2 Compact system (BioMérieux SA, Marcy l’Etoile, France), the disc diffusion method, and broth microdilution (BMD) for colistin. Whole-genome sequencing (WGS) did not uncover evidence of any mobile colistin resistance (mcr) genes, although the mgrB gene of seven isolates appeared to be disrupted by insertion sequences (ISKpn25 or ISKpn26). Possible deleterious missense mutations were found in phoP (L4F), phoQ (Q426L, L26Q, L224Q, Q317K), pmrB (R256G, P95L, T157P, V352E), and crrB (P151S) genes. The identified isolates belonged to the following clonal lineages: ST101 (n = 6), ST147 (n = 5), ST258 (n = 2), and ST307 (n = 1). All strains harbored IncF plasmids. OXA-48 producers carried IncL and IncR plasmids, while one blaNDM-1 genome was found to harbor IncC plasmids. Ceftazidime–avibactam remains a therapeutic option for KPC-2 and OXA-48 producers. Resistance to meropenem–vaborbactam has emerged in some blakPC-2-carrying isolates. Our study demonstrates that the results of WGS can provide essential evidence for the surveillance of antimicrobial resistance.
The gamma-ray deficit toward the Galactic center

Le flux Rγ (E>300 MeV) des quelques centaines de parsecs du centre de la Galaxie est pratiquement d'un ordre de grandeur plus faible que la valeur prevue a partir des masses H 2 prevues au centre et a partir de l'emissivite Rγ moyenne mesuree pour le disque. Cela implique que dans le centre galactique l'emissivite Rγ est anormalement faible ou que l'hydrogene moleculaire est d'un ordre de grandeur moins abondant que les estimations faites a partir d'observations CO
Frontostriatal Functional Connectivity Underlies the Association between Punishment Sensitivity and Procrastination

Procrastination is defined as putting off an intended course of action voluntarily despite the harmful consequences. Previous studies have suggested that procrastination is associated with punishment sensitivity in that high punishment sensitivity results in increased negative utility for task performance. We hypothesized the effects of punishment sensitivity on procrastination would be mediated by a network connecting the caudate nucleus and prefrontal cortex, both of which have been previously associated with self-control and emotional control during procrastination. We employed voxel-based morphometry (VBM) and resting-state functional connectivity (rsFC) to examine the neural substrates of punishment sensitivity and its relationship with procrastination (N = 268). The behavioral results indicated a strong positive correlation between measures of punishment sensitivity and procrastination. The VBM analysis revealed that the gray matter (GM) volume of the right caudate was significantly positively correlated with punishment sensitivity. The primary rsFC analysis revealed connectivity between this caudate location and the bilateral middle frontal gyrus (MFG) was significantly negatively correlated with punishment sensitivity. A mediation model indicated punishment sensitivity completely mediated the relation between functional connectivity within a caudate–bilateral MFG network and procrastination. Our results support the theory that those with higher punishment sensitivity have weaker effective emotional self-control supported by the caudate–MFG network, resulting in greater procrastination.
Banking on Snow: Bank Capital, Risk, and Employment

How does small-firm employment respond to exogenous labor productivity risk? We find that this depends on the capitalization of firms’ local banks. The evidence comes from firms employing workers whose productivity depends on the weather. Weatherinduced labor productivity risk reduces this employment, and this effect is stronger in regions where the regional banks have less equity capital. Bank capitalization also proxies for the extent to which the regional banks’ borrowers can obtain liquidity when the regions are hit by weather shocks. We argue that, as liquidity providers, wellcapitalized banks support economic adaptation to climate change. ∗We thank Tim Eisert, Bernd Fitzenberger, Kilian Huber, Marcin Kacperczyk, Botond Köszegi, Jan Stuhler, Daniel Schäfer, Franz Hartl, Wolfgang Kleemann, Conny Wunsch and participants of the SOLE-EALEAASLE World Conference and the European Finance Association Meetings, as well as seminar participants of the Leopoldina (Bonn) and in Budapest, Frankfurt, Lancaster, Linz, Norwich, Vienna, and Würzburg. Thanks to the Austrian Central Bank (ÖNB Jubiläumsfonds) and the Austrian Christian Doppler Society for support. All errors are our own. “making finance flows [. ] consistent with climate-resilient development. ” from Article 2 of the Paris Agreement, UNFCCC (2016)
Recent advances in electrode material for symmetrical solid oxide fuel cells and way forward sustainability based on local mineral resources

Solid oxide fuel cells (SOFCs) are eco‐friendly and yet highly efficient power generation devices. However, SOFCs face some commercial issues with durability, reliability, sustainability, and fabrication costs. In recent years, a unique design idea of symmetrical cell configuration of SOFCs with similar anode and cathode materials, commonly known as SSOFC or SFC has piqued the interest among researchers. The present review article attempts to comprehensive reported research related to the current development of new and promising advances in SSOFCs. Until now, most research on SSOFCs has focused on identifying appropriate materials for the system configuration electrodes. The progress and advances in structures and electrode materials for SSOFCs are summarised here. The electrical and electrochemical behaviours of SSOFCs as well as the performance comparisons with the common conventional SOFCs, in the aspect of electrode materials, are analysed and discussed. This review article provides a comprehensive data source for further investigation and exploration related to this topic towards sustainable, low‐cost, and viable commercialisation of this green fuel cell, especially by utilising local minerals from one's country.