Miracle-dz/UniFAR-FTUs huggingface dataset:
Comparison of the safety and clinical efficacy of glucagon-like peptide-1 receptor agonist and α-glucosidase inhibitor among Chinese people with type 2 diabetes

Purpose: To compare the safety and efficacy of once-weekly prescription of GLP-1 receptor agonists (adlyxin) with those of α-glucosidase inhibitor (voglibose) and other reference drugs (RD). Methods: A total of 1250 stable diabetes-mellitus patients from the Department of Endocrinology, Ningbo No. 6 Hospital, Ningbo, Zhejiang 315040, China were enrolled in this study between Feb 2018 and Jan 2020. They were treated using physical exercise and diet chart therapy. The patients were assigned to three different groups and administered GLP-1 receptor agonist (GLP-1RA) or glucosidase inhibitor (voglibose) and other reference drugs (RDs). The safety and efficacy of these drugs were compared. The primary endpoint was the number of treatment-emergent adverse events (TEAEs), while the secondary endpoints were based on symptomatic hypoglycaemic episodes and other biochemical parameters. Results: Patients who used α-glucosidase inhibitors had the highest percentage of TEAEs, when compared to those on GLP-1RAs and RDs (p < 0.05). No specific cases of severe hypoglycaemia were observed among all the groups. Users of adlyxin also achieved significant glycaemic control at the end of the study period, when compared to voglibose users, with a mean HbA1c baseline of 8.2 % (p < 0.05). Conclusion: These results indicate that the GLP-1 receptor agonist adlyxin achieved good glycaemic control. Thus, it has beneficial potential for use among type 2 diabetes in the Chinese population.
Regional Geoscience Studies and Petroleum Potential, Peel Plateau and Plain, Northwest Territories and Yukon: Project Volume

Initiated by the Northwest Territories Geoscience Office, the project Regional Geoscience Studies and Petroleum Potential, Peel Plateau and Plain, Northwest Territories and Yukon (2005 to 2009) involved partners from the Yukon Geological Survey, Geological Survey of Canada, as well as universities and industry. The research addresses the need for modern petroleum geoscience data and interpretation in this underexplored and prospective area of Canada’s North in close proximity to the proposed Mackenzie Gas Project pipeline route. The findings from this study will help to stimulate future resource exploration and development, bringing economic benefits to the region. The research team coupled field-based studies with subsurface analytical techniques to evaluate the study area’s hydrocarbon potential. Over 70 interim publications have been produced. Key 2009 final deliverables include: a) this volume which compiles chapters devoted to several stratigraphic petroleum plays, along with structural and petroleum systems elements; and b) a digital geodatabase (or atlas) of spatially based data collected during the course of the project. The result is a comprehensive body of geoscience work for Peel area which will be useful to in oil and gas exploration and for regional land use and business planning endeavours. 1 Leanne.Pyle@NRCan-RNCan.gc. ca; Geological Survey of Canada – Pacific, Sidney, BC 2 Adrienne_Jones@gov.nt. ca; Northwest Territories Geoscience Office, Yellowknife, NT
Telemedicine in Cardiology: Modern Technologies to Improve Cardiovascular Patients’ Outcomes—A Narrative Review

The registration of physical signals has long been an important part of cardiological diagnostics. Current technology makes it possible to send large amounts of data to remote locations. Solutions that enable diagnosis and treatment without direct contact with patients are of enormous value, especially during the COVID-19 outbreak, as the elderly require special protection. The most important examples of telemonitoring in cardiology include the use of implanted devices such as pacemakers and defibrillators, as well as wearable sensors and data processing units. The arrythmia detection and monitoring patients with heart failure are the best studied in the clinical setting, although in many instances we still lack clear evidence of benefits of remote approaches vs. standard care. Monitoring for ischemia is less well studied. It is clear however that the economic and organizational gains of telemonitoring for healthcare systems are substantial. Both patients and healthcare professionals have expressed an enormous demand for the further development of such technologies. In addition to these subjects, in this paper we also describe the safety concerns associated with transmitting and storing potentially sensitive personal data.
Effect of hempseed meal on performance, egg quality and egg yolk fatty acids content in laying quails

In this study, the laying performance, external egg quality, egg yolk colour and fatty acids profile of quails (Coturnix coturnix japonica) fed on diets containing hemp seed meal (HSM) were determined. During 8 weeks trial, a total of 150, 10-weeks-old laying quails were used. Five diets were formulated to contain HSM at the level of 0 (control),5, 10, 15, and 20% that represented as 0 HSM, 5 HSM, 10 HSM, 15 HSM and 20 HSM, respectively.The performance parameters were not significantly (P>0.05)influenced by the dietary HSM contents. Eggshell ratio, eggshell breaking strength, egg shape index, egg yolk index and egg yolk colour values were not significantly (P>0.05) influenced by the dietary HSM, whereas eggshell thickness was significantly (P<0.05) affected. The albumen index has been significantly (P<0.05) increased by increasing in the HSM level in the diets. The HSM supplementation to the diets was effective on fatty acid composition and total saturated fatty acids, total mono unsaturated fatty acids and total polyunsaturated fatty acids content of the egg yolk depending on the addition level. In conclusion, HSM can be used to increase egg total monounsaturated fatty acids and especially omega-3 fatty acids without unfavourable effects on the performance and egg quality parameters.
Synergistic Action of PGPR and Biofungicide with Active Ingredient of Cladosporium clasporioides to Control White Rust on Chrysanthemum

The application of antagonist microbes to control significant diseases on crops is an essential issue in the eco-friendly and sustainable agriculture of the chrysanthemum production system. The application of antagonist consortiums is expected to synergistically suppress the pathogen more effectively than a single microbe, thus increasing the marketable flower yield. The research is carried out to evaluate the single and combined application of antagonists C. ladosporioides and PGPRs, B. subtilis, and P. flourescens to control white rust in Chrysanthemum. The results show that there is no cumulative effect from the combination of biofungicide and the PGPR on disease suppression, disease incidence, and plant growth improvement than single antagonist treatments. Compared to synthetic fungicide, biofungicide and the PGPR treatments give higher parasitism intensity, though the values were negligible among the treatments. The lowest disease intensity is recorded from synthetic fungicide treatment. The improvement of flower quality due to biofungicide, PGPR, and synthetic fungicide treatments was found only on the longer vase life than untreated plants. Observation on the compatibility of antagonists with PGPRs are still needed to increase the effectiveness in controlling white rust in Chrysanthemum.
Using an Assessment System for Data-Driven Reform

The present study employed a difference-in-difference approach to determine the impact of a technologically enhanced diagnostic and formative assessment system implemented in one US state in kindergarten through third grade on school-level end-of-year third-grade reading test scores and percentage of students receiving special education services. Data were obtained for 795 elementary schools that implemented the assessment system in a staggered progression across multiple years. The analysis estimated the effect of the assessment system on the entire third-grade sample, and by selected demographic characteristics. Results showed no effect of the assessment system on average end-of-year reading scores or school-level percentage of students receiving special education services. Follow-up models including time and fidelity information also obtained null results overall. Given the null, schools should consider modifications to the ways they obtain, manage, and use assessment data.
Efforts Towards a Validated Time-Domain Model of an Oscillating Water Column with Control Components

As part of the development process of a proposed offshore floating wind/wave platform, a scale-model testing pro- gramme has been carried out at a narrow tank facility on a single oscillating water column (OWC) device. Previous proof-of- concept testing was performed on a scale model of the proposed platform comprising thirty-two OWCs with control components. That testing programme, implemented at the Hydraulic and Maritime Research Centre, demonstrated the feasibility of the concept. However, the large number of interacting components in this complex system results in difficulties when attempting to study and model numerically the hydrodynamic and thermo- dynamic processes at work within the OWCs during operation. In order to better study these processes, the subsequent phase of narrow tank testing was planned based on a single-chamber OWC model as described herein. This model was constructed with similar dimensions and cross-sectional profile to that of one OWC chamber in the larger model. Various control components can be added to and removed from the new model to investigate in a systematic fashion the effect of each component. Theory to numerically model the OWC in various configurations has been developed. A comparison between the tank test results and those obtained for a specific setup is presented. Index Terms—tank testing, numerical modelling, oscillating water column, control valves, plenum.
Influence of Green Accounting and Environmental Performance on Profitability

The purpose of this research is to gather empirical evidence about the effect of green accounting and environmental performance on profitability, either separately or concurrently. The population in this study consists of 107 companies listed on the Indonesia Stock Exchange in the mining sector and the goods industry sector consumption. Purposive sampling with criteria set to produce 77 observational data was used to sample as much as possible. In this study, data was gathered through documentation in the form of annual reports and company sustainability reports. Based on the findings of the research, it is possible to conclude that, while the use of green accounting is voluntary, its impact on profitability is greater than that of environmental performance. The implications of this research explain how the company can improve environmental cost efficiency so that it can be used as the basis for the company's consideration before determining the expected level of profitability.
The dominant modes of the long rains interannual variability over Tanzania and their oceanic drivers

Mitigating the impacts of droughts and floods over East Africa (EA) may largely be possible through accurate predictions of the long rains (March–May). Though the close interannual variability between the long rains, Indian and Pacific Oceans has been widely studied, Tanzania's long rain variability remains unclear. This paper examines the Tanzanian long rains dominant modes through an empirical orthogonal function (EOF) analysis, and their relationship with winter sea surface temperature (SST) for the period 1951–2018. Correlation and composite analyses were applied to explore the associated mechanisms. The first EOF (EOF1) mode is characterized by negative anomalies over Tanzania. The second EOF (EOF2) mode depicts positive (negative) anomalies over northern (southern) Tanzania. The third EOF (EOF3) mode reveals positive (negative) anomalies over eastern (western) Tanzania. EOF1 is closely related to the SST anomalies (SSTAs) in the southeastern Indian Ocean (SEIO). When the SSTAs are positive, they subsequently linked to upper (lower) level convergence (southeasterly winds) over Tanzania. Associated with this convergence entails a sinking motion, leading to a negative rainfall anomaly. The southeasterly winds indicate an early onset of the southeast monsoon, leading to normal rainfall been recorded. EOF2 is linked to the SSTAs in the central Pacific (CP). Positive SSTAs are related to reversed Walker circulation (WC) over northern Tanzania, while the upper‐level convergence was observed around southern Tanzania. This meridional dipole vertical motion pattern enhances (suppresses) rainfall anomalies. EOF3 is associated with mega El Niño–Southern Oscillation (ENSO)‐like SSTAs. The SSTAs are related to eastward shift of WC over the Indian Ocean, and zonal cell over the western Indian Ocean with rising limb is located east of Tanzania. The ascending motion enhances rainfall over eastern Tanzania. Predictions based on the SEIO, CP, and mega ENSO index may significantly support long rains prediction efforts and provide early warning.
Severe Maternal Outcomes and Quality of Maternal Health Care in South Ethiopia

Objective To assess the incidence of severe maternal outcomes (SMO) and quality of maternal health care in south Ethiopia. Methods A facility-based prospective study was conducted in three hospitals among all women who presented while pregnant, during and after childbirth between 12 July and 26 November 2018. Participants were followed from the time of admission to discharge. The World Health Organization (WHO) maternal near-miss (MNM) approach was used to assess SMO indicators and quality of maternal health care. Results Of 2880 live births, 315 had potentially life-threatening conditions and 108 had SMOs (90 MNM and 18 maternal deaths). The SMO incidence ratio was 37.5 per 1000 live births (95% CI 30.6–44.4) and MNM incidence ratio was 31.3 per 1000 live births (95% CI 24.9–37.7). The ratio of near-miss to maternal deaths was 5:1. The hospitals’ maternal mortality ratio (MMR) was 625 per 100,000 live births. Most (82.1%) SMO cases were referred from other health facilities. The most common cause of SMO was eclampsia (37%) followed by postpartum haemorrhage (33.3%). The highest mortality index (MI) was among women with sepsis (27.3%). The intensive care unit (ICU) admission rate was 13% for women with SMO and 83.3% of maternal deaths occurred without ICU admission. Conclusion The SMO ratio was comparable to other studies in the country. Most women with SMO were referred from other health facilities, which demonstrate the presence of the first delay (seeking care) and/or the second delay (reaching care) in the study area. The study suggests that effectively using the ICU, reducing delays, and improving the referral system may reduce SMO and improve the quality of care in the hospitals. Furthermore, continuous reviewing of SMO is needed to learn what treatment was given to women who experienced complications in the hospitals.
The effects of supply chain flexibility on customer responsiveness: the moderating role of innovation orientation

Abstract We investigate the link between supply chain (SC) flexibility and responsiveness. Our study contributes to the literature by examining how SC flexibility, as a multi-dimensional construct, affects customer responsiveness and if this relationship is moderated by the innovation orientation of a firm. Using data from 225 Swedish manufacturers, we test our proposed empirical model and find empirical support for the positive effects of the supply chain flexibility dimensions on customer responsiveness. In addition, we found support for the strengthening effect of innovation orientation on the link between internal flexibility and customer responsiveness. The empirical validation of the relationship between the multi-dimensional SC flexibility and customer responsiveness which is moderated by the innovation orientation is an original contribution to both theory and practice.
Carbon dynamics and sequestration by urban mangrove forests of Dar es Salaam, Tanzania

This study intended to 1) determine spatial and temporal changes of mangrove forests, 2) identify drivers of mangrove deforestation and forest degradation, 3) determine historical carbon storage, sequestration and deforestation emissions by mangrove forests, and 4) determine whether mangrove forests are a source or sink of CO2 in Dar es Salaam, Tanzania. Mangrove forests have decreased from 4,813 hectares in 1986 to 1961 hectares in 2016. The following were prominent drivers of deforestation in descending order: clearing mangrove forests for salt pans; hotel construction; settlement; and charcoal making. Tree removals for firewood and building poles were also prominent drivers of mangrove forest degradation. Similarly, carbon stored in mangrove forests has decreased from 1,131,055 tonnes CO2e in 1986 to 460,835 tonnes CO2e in 2016. Sequestration of CO2 by mangrove forests is estimated at 133,516 (1986-1995); 106,110 (1995-2006) and 69,616 (2006-2016) tonnes CO2e year-1. Conversely, mangrove deforestation has resulted in emissions of about 27,400, 16,500 and 24,000 tonnes CO2e year-1 in 1986-1995, 1995- 2006 and 2006-2016, respectively. Urban mangrove forests play an important environmental role in mitigating climate change and amelioration of local weather through the large carbon stocks they store and sequester. Mangrove forests in the study area remain a net carbon sink, however, the sink role played by mangrove forests in the study area is decreasing rapidly. The declining spatial and temporal trends of urban mangrove forest cover has resulted in a systematic decrease in the total carbon stored and sequestered by mangrove forests. In the absence of timely measures of preserving and rehabilitating degraded mangrove areas, the mangrove forests of Dar es Salaam may become the source of CO2. The study recommends effective urban land use planning and effective law enforcement to ensure a win-win situation through sustained ecosystem services offered by urban mangrove forests to support economic growth.
Green Synthesis of Iron Oxide Nanoparticles Using Ceratonia Siliqua L. Aqueous Extract: Optimization, Characterization, Stabilization and Evaluation of Its Antibacterial Activity Against Gram-Positive and Gram-Negative Bacteria

This study focused on the optimization of reaction parameters for a simple and reliable method for the green synthesis of iron oxide nanoparticles (gIONPs). The potential of aqueous extract of the Ceratonia siliqua L. (carob pod) as a reducing, capping, and stabilizing agent for gIONPs synthesis, and the antibacterial activity of as-synthesized gIONPs was investigated. The synthesis parameters were determined as the concentration of iron ion, the concentration of extract, pH of extract, temperature, stirring rate, and reaction time. The significance of the studied factors in controlling the particle size distribution of nanoparticles was quantitatively evaluated via analysis of variance (ANOVA). Iron oxide nanoparticles were produced at the optimum parameters with an average zeta potential of + 40.75 ± 1.22 mV, hydrodynamic size of 78 ± 22 nm, and a polydispersity value of 0.42 ± 0.06, respectively. gIONPs showed the highest inhibition zones of 24 mm and 21 mm in 250 mg/mL concentration against Gram-negative Escherichia Coli and Gram-positive Staphylococcus aureus, respectively. Strong antibacterial activity was observed when compared with the standard antibiotics. The findings of the study revealed that the highly stable and antibacterial iron oxide nanoparticles can be synthesized through the adjustment of the reaction parameters by eliminating chemicals and increasing awareness of green chemistry.
Dynamic optimization of elevator group control based on artificial immune algorithm for inter-floor peak traffic during lunch-time

Inter-floor peak traffic is a combination of up-peak traffic,down-peak traffic and inter-floor traffic.Lunch- peak traffic is a typical pattern of vertical transportation within a modern office building.Based on the characteristics of lunch-peak traffic,a dynamic optimization strategy of elevator group control is proposed in this paper by utilizing artificial immune algorithm.This strategy has a two-level control structure.One structure is the locally optimal assignment of a hall call performed by THV algorithm;the other is the globally optimal assignment of all hall calls,which is executed periodically by artificial immune algorithm.Compared to THV algorithm,the newly proposed strategy decreased the average system waiting time by 21.26%. Simulation results demonstrated that the performance of elevator system during lunch-time is greatly improved under control of the proposed strategy in this paper.
Peripartum Cardiomyopathy: Diagnostic and Prognostic Value of Cardiac Magnetic Resonance in the Acute Stage

This study aimed to evaluate the diagnostic and prognostic value of cardiac magnetic resonance in acute peripartum cardiomyopathy (PPCM). A total of 17 patients with PPCM in the acute stage and 15 healthy controls were retrospectively analyzed regarding myocardial function, edema, late gadolinium enhancement (LGE), and T1 and T2 mappings (T1, T2). Echocardiographic follow-ups were performed. Functional recovery was defined as a left ventricular ejection fraction (LVEF) of ≥50%. Patients with PPCM displayed biventricular dysfunction with reduced myocardial strain parameters and left ventricular and atrial dilatation, as well as diffuse myocardial edema (T2 signal intensity ratio: 2.10 ± 0.34 vs. 1.58 ± 0.21, p < 0.001; T1: 1070 ± 51 ms vs. 980 ± 28 ms, p = 0.001; T2: 63 ± 5 ms vs. 53 ± 2 ms, p < 0.001). Visual myocardial edema was present in 10 patients (59%). LGE was positive in 2 patients (12%). A total of 13 patients (76%) showed full LVEF recovery. The absence of visual myocardial edema and impairment of strain parameters were associated with delayed LVEF recovery. Multivariable Cox regression analysis revealed global longitudinal strain as an independent prognostic factor for LVEF recovery. In conclusion, biventricular systolic dysfunction with diffuse myocardial edema seems to be present in acute PPCM. Myocardial edema and strain may have prognostic value for LVEF recovery.
Research on the determinants of public employees’ quality of work life: relocation of Korean government agencies to Sejong City

ABSTRACT This research aims to reflect current Korean public sector issues, such as emphasis on innovation and humanistic values (quality of life [QOL] and quality of work life [QWL]), and fill the gap in public service motivation (PSM) research. To analyze the determinants of QWL, the moderating effects of a non-work domain factor (QOL) between work domain factors (PSM, job autonomy, innovative culture, and innovative performance) and QWL are investigated. Furthermore, a comparative analysis of a group relocated to Sejong and a stationary group was conducted. Using survey data, this study reveals that the QWL of the relocation group is lower than that of their counterparts, and that job autonomy, innovative culture, and QOL are effective antecedents of QWL in both groups. In contrast, the effects of PSM and the moderating effects of QOL diverge depending on relocation status. Consequently, this study has both theoretical and practical implications.