Miracle-dz/UniFAR-FTUs huggingface dataset:
CLEP_A_307762 325..333

Point your SmartPhone at the code above. If you have a QR code reader the video abstract will appear. Or use: https://youtu.be/eh0mBFzrWBk Purpose: Register-based clinical research is important. However, it is essential that the collected data are reliable for the registers to be a valuable source of information. This study evaluated the quality of humeral fracture data in the Swedish Fracture Register (SFR) and in the Swedish National Patient Register (NPR). Furthermore, a model for improved case ascertainment was developed for future validation processes. Materials and Methods: Data were obtained from the NPR and SFR for all individuals aged ≥16 years with an acute humeral fracture ICD-code treated at Sahlgrenska University Hospital. The true number of humeral fractures (“gold standard”) was determined by crosslinkage between the two registers and a medical charts review. The completeness of registrations in each register was measured as the proportion of registrations compared with the gold standard, and accuracy was measured as positive predictive values (PPV). Results: The NPR demonstrated a high level of completeness (97%) and lower accuracy (PPV 70%) for acute humeral fractures, whereas the SFR had slightly lower completeness (88%) but perfect accuracy (PPV 100%). The most common systematic error was the registration of re-admissions as acute fractures in the NPR (84% of all erroneous registrations). With this knowledge, an adjustment model for NPR data was constructed to increase the accuracy of fracture registrations (PPV 92%) without excluding valid registrations. Conclusion: Data from the NPR tend to overestimate the true number of fractures, and proper case selection is needed in order for the data to function as a solid basis for epidemiological research and healthcare planning. In contrast, the SFR constitutes a complete, accurate and efficient source of information.
RENT-SEEKING COMPETITION FROM STATE COFFERS

This paper incorporates competition for fiscal transfers (or, equivalently, rent seeking from state coffers) into a standard general equilibrium model of economic growth and endogenously chosen fiscal policy. The government generates tax revenues, but then each selfinterested individual agent tries to extract, for his own personal benefit, a fraction of these revenues. Extracted tax revenues could alternatively be used to finance economy-wide infrastructure. We look at a Nash equilibrium in individual agents’ behavior, and then investigate what the society should do to discourage rent-seeking competition. The focus is on the optimal size of public sector.
Lecturers and Education Experts Perceptions of Private Universities in Mogadishu, Using PESTEL Analysis and AHP

This paper aims to reveal the perception of lecturers and education experts towards private universities in Mogadishu, Somalia by using PESTEL analysis and Analytical Hierarchy Process (AHP). The author used Excel, SPSS, and SPSS Modeler for data analysis and cluster model quality as well as RATTLE application and AHP online calculator to determine the optimal number of clusters of the study and the priority Rank of PESTEL factors. The results of the study from the view of lecturers explored that the macro-environment that the private universities in Mogadishu operate within is a good support level in their current aims. The results also in light of the view of education experts showed the priority rank of PESTEL factors for the private universities in Mogadishu to their current aims; whereas the political factor scored up the priority one, the economic factor recorded second priority, the social factor got third and the legal factor obtained the fourth priority rank, while the technology factor gained the fifth rank and the environmental factor the sixth rank. Finally, the study addressed recommendations around the factors that could contribute to the enhancement of private universities in Mogadishu, Somalia.
Deep neural network-based automatic system for electricity meter reading in Nepal

— This work proposes a new system that Nepalese energy/utility companies can implement to obtain better accuracy of energy usage scenarios. The proposed system can also be used to reduce undesired non-technical losses in the electricity market. This reduction is achieved by replacing the middle agents with an intelligent system that can identify energy meter readings and calculate accurate billing information correctly. As part of the system, common smartphones are used for taking pictures of energy meters by the owners, who upload them to the central server. The central server then utilizes a deep neural network – YOLOv3 – to detect and identify energy meter counters and digits, from which current energy consumption is extracted. This extracted value is then used for calculating the billing information.
Abscisic acid (ABA) induces production of reactive oxygen species (ROS) and nitric oxide (NO), elevation of the cytosolic free calcium ion concentration ([Ca

species (ROS) and nitric oxide (NO), elevation of the cytosolic free calcium ion concentration ([Ca 2 + ] cyt ) and cytosolic pH (pH cyt ), and activation of S-type anion channels in guard cells, causing stomatal closure. To investigate whether Arabidopsis Two pore channel 1 ( AtTPC1 ) that encodes the slow vacuolar (SV) channel is involved in stomatal closure, we examined stomatal movements and mobilization of second messengers in the attpc1-2 loss-of-function mutant in response to ABA, methyl jasmonate (MeJA) and Ca 2 + . Both ABA and MeJA elicited production of ROS and NO, [Ca 2 + ] cyt oscillations, cytosolic alkalization and activation of S-type anion channel currents to lead to stomatal closure in the attpc1-2 mutant as well as the wild type. Unlike the wild type, in the attpc1-2 mutant exogenous Ca 2 + neither induced stomatal closure nor activated plasma membrane S-type anion channel currents despite [Ca 2 + ] cyt elevation. These results indicate that AtTPC1 functions in response to external Ca 2 + but not to ABA and MeJA in Arabidopsis guard cells and suggest that AtTPC1 could be involved in priming of plasma membrane S-type anion channels by external Ca 2 + in Arabidopsis guard cells.
CD14 mediates TLR4 endocytosis and Syk and IRF3 activation in epithelial cells, and impairs neutrophil infiltration and Pseudomonas aeruginosa killing in vivo

In the current study, we examined the role of CD14 in regulating LPS activation of corneal epithelial cells and Pseudomonas aeruginosa corneal infection. Our findings demonstrate that LPS induces TLR4 internalization in corneal epithelial cells and that blocking with anti-CD14 selectively inhibits TLR4 endocytosis, Syk and IRF3 phosphorylation, and production of CCL5/RANTES and IFN-β , but not IL-8. Using a murine model of P. aeruginosa corneal infection, we show that although infected CD14 corneas produce less CCL5, they exhibit significantly increased CXC chemokine production, neutrophil recruitment to the corneal stroma and bacterial clearance than C57BL/6 mice. We conclude that CD14 has a critical role in mediating TLR4 signaling through IRF3 in resident corneal epithelial cells and macrophages, and thereby modulates TLR4 cell surface activation of the MyD88/NFκB/AP-1 pathway and production of CXC chemokines and neutrophil infiltration to infected tissues.
COAGULATION PARAMETERS, PLATELET COUNT AND D-DIMER LEVEL CHANGES IN PREECLAMPSIA AND NORMAL PREGNANCIES IN KHARTOUM STATE

Background: Preeclampsia (P-E) is an obstetric disorder with high morbidity and mortality rates but without clear pathogenic. The dysfunction of the blood coagulationfibrinolysis system is a silent characteristic of preeclampsia that varies in severity, and necessitates different treatments. A better understanding of the abnormalities of coagulation in the preeclamptic and eclamptic patient may allow the clinician to provide improved management & possibly peripartum therapy. Therefore, it is necessary to find suitable predictors for the onset and severity of preeclampsia. Aim and objective: this study designed to compare the coagulation profile, platelet count and D-dimer level in normal pregnancy, severe preeclampsia, and preeclampsia patients to determine the potential indicator of the onset and the severity of preeclampsia. Materials and methods: The study was concluded in the Omdurman Maternity hospital and Saudi hospital in Khartoum state during period between May and October 2016.A 50 confirmed cases of preeclamptic/severs preeclamptic patients and 50 normal pregnant women in the third trimester were recruited. Coagulation profile including prothrombin time (PT) activated partial thromboplastin time (APTT), Platelet count and D-dimer test were measured and compared among the study populations. Results: Mean value of platelet count was significantly lower in the case group than in control 178. 36 versus 267. 64X10 9 , (P= 0.000). Mean vales of APTT (34.60versus 37.07sec) and PT (10.97 versus, 12.54sec) tests, were significantly reduced in control than case group (p= 0.00). D-dimer level (2.21 versus 1.04mg/ml) was significantly greater in case than control group (p=0.00). All coagulation parameters and platelet count did not show any statistical differences between sever preeclamptic and preeclamptic groups . While D.dimer level was markedly greater in sever preeclamptic cases than preeclamptic cases (2.73versus 1.10mg/ml (p= 0.000). Conclusion: Raised D-dimer is fairly good indicator of severe preeclampsia and alarming sign for aggressive treatment.
Modeling the Impact of Communications Technologies on Travel Behavior and Land Use

The widespread use of communications technologies has changed the way people travel. Transport modeling offers the opportunity to analyze this impact and test innovations, policies, and future trends before they actually happen. The impact of smartphones, GPS, and telework has been researched insufficiently, despite the impact of these technologies on travel behavior. Autonomous vehicles are expected to be widely available in the near future, but their impact on travel behavior is largely unknown. Last but not least, social networks have a dominating impact on the activities people pursue, the destinations they choose, the mode they use, and with whom they travel. This paper describes a framework for an integrated land use–transport model for analyzing the impact of communications technologies on travel behavior. Social networks are simulated explicitly. The impact of communications technologies on both land use, such as the impact on a housing search, auto ownership, or work place choice, as well as travel behavior such as activity generation, destination choice, or mode choice, can be simulated with this modeling suite.
for the Induction of Cytokine Release Domain-2 Modulates Specific TLR Pathways Nucleotide-Binding Oligomerization

The recognition of peptidoglycan by cells of the innate immune system has been controversial; both TLR2 and nucleotide-binding oligomerization domain-2 (NOD2) have been implicated in this process. In the present study we demonstrate that although NOD2 is required for recognition of peptidoglycan, this leads to strong synergistic effects on TLR2-mediated production of both pro- and anti-inﬂammatory cytokines. Defective IL-10 production in patients with Crohn’s disease bearing loss of function mutations of NOD2 may lead to overwhelming inﬂammation due to a subsequent Th1 bias. In addition to the potentiation of TLR2 effects, NOD2 is a modulator of signals transmitted through TLR4 and TLR3, but not through TLR5, TLR9, or TLR7. Thus, interaction between NOD2 and speciﬁc TLR pathways may represent an important modulatory mechanism of innate immune responses. The Journal of Immunology, 2005, 174: 6518–6523.
A model of angular speed detection for bees

7 A fly or bee’s responses to widefield image motion depend on two basic parameters: 8 temporal frequency and angular speed. Rotational optic flow is monitored using temporal 9 frequency analysers, whereas translational optic flow seems to be monitored in terms of 10 angular speed. Here we present a possible model of an angular speed detector which 11 processes input signals through two parallel channels. The output of the detector is taken as 12 the ratio of the two channels’ outputs. This operation amplifies angular speed sensitivity 13 and depresses temporal frequency tuning. We analyse the behaviour of two versions of this 14 model with different filtering properties in response to a variety of input signals. We then 15 embody the detector in a simulated agent’s visual system and explore its behaviour in 16 experiments on speed control and odometry. The latter leads us to suggest a new algorithm 17 for optic flow driven odometry. 18 19
Alhotan, Abdulaziz and Yates, Julian and Zidan, Saleh and Haider, Jul- fikar and Silikas, Nikolaos (2021) Flexural Strength and Hardness of Filler- Reinforced PMMA Targeted for Denture Base

The aim of this work was to evaluate the flexural strength and surface hardness of heatcured Polymethyl methacrylate (PMMA) modified by the addition of ZrO2 nanoparticles, TiO2 nanoparticles, and E-glass fibre at different wt. % concentrations. Specimens were fabricated and separated into four groups (n = 10) to measure both flexural strength and surface hardness. Group C was the control group. The specimens in the remaining three groups differed according to the ratio of filler to weight of PMMA resin (1.5%, 3%, 5%, and 7%). A three-point bending test was performed to determine the flexural strength, while the surface hardness was measured using the Vickers hardness. Scanning Electron Microscope (SEM) was employed to observe the fractured surface of the specimens. The flexural strength was significantly improved in the groups filled with 3 wt. % ZrO2 and 5 and 7 wt. % E-glass fibre in comparison to Group C. All the groups displayed a significantly higher surface hardness than Group C, with the exception of the 1.5% TiO2 and 1.5% ZrO2 groups. The optimal filler concentrations to enhance the flexural strength of PMMA resin were between 3–5% ZrO2, 1.5% TiO2, and 3–7% E-glass fibre. Furthermore, for all composites, a filler concentration of 3 wt. % and above would significantly improve hardness.
AHEART April 47/4

Kjekshus, Harald, Otto A. Smiseth, Randi Klinge, Erik Øie, Marit E. Hystad, and Håvard Attramadal. Regulation of ET: pulmonary release of ET contributes to increased plasma ET levels and vasoconstriction in CHF. Am J Physiol Heart Circ Physiol 278: H1299–H1310, 2000. — Endothelin (ET) contributes to the increased systemic vascular resistance and elevated cardiac filling pressures seen in congestive heart failure (CHF). We investigated to what extent ET-mediated vasoconstriction in CHF occurs through an endocrine action of elevated plasma ET or by an autocrine/ paracrine mechanism related to induction of vascular ET gene expression. Three weeks of pacing (225 beats/min) induced a marked release of ET-1 from the pulmonary circulation with a sixfold elevation of arterial plasma ET in CHF pigs compared with sham-operated pigs. Arterial plasma ET was the strongest and only independent predictor of systemic vascular resistance. In contrast, vascular preproET-1 and ET-receptor mRNA expression were unaltered or decreased in CHF pigs and did not correlate with indexes of vascular tone. However, myocardial preproET-1 mRNAexpression increased twofold in CHF pigs. PreproET-2 and preproET-3 mRNAs were not detectable in cardiovascular tissues. In conclusion, plasma ET was markedly increased because of an augmented release from the pulmonary circulation during CHF, and arterial plasma ET correlated with systemic vascular resistance. The absence of ET induction in the peripheral vasculature suggests that ET increases vascular tone during CHF by an endocrine, not an autocrine/ paracrine, mechanism.
Prostate Cancer and Supplementation With -Tocopherol and -Carotene: Incidence and Mortality in a Controlled Trial

Background: Epidemiologic studies have suggested that vitamin E and b-carotene may each influence the development of prostate cancer. In the Alpha-Tocopherol, Beta-Carotene Cancer Prevention Study, a controlled trial, we studied the effect of a-tocopherol (a form of vitamin E) and b-carotene supplementation, separately or together, on prostate cancer in male smokers.Methods: A total of 29 133 male smokers aged 50–69 years from southwestern Finland were randomly assigned to receivea-tocopherol (50 mg), b-carotene (20 mg), both agents, or placebo daily for 5–8 years (median, 6.1 years). The supplementation effects were estimated by a proportional hazards model, and two-sidedP values were calculated. Results:We found 246 new cases of and 62 deaths from prostate cancer during the follow-up period. A 32% decrease (95% confidence interval [CI] = −47% to −12%) in the incidence of prostate cancer was observed among the subjects receivinga-tocopherol (n = 14 564) compared with those not receiving it (n = 14 569). The reduction was evident in clinical prostate cancer but not in latent cancer. Mortality from prostate cancer was 41% lower (95% CI = −65% to −1%) among men receivinga-tocopherol. Among subjects receiving b-carotene (n = 14 560), prostate cancer incidence was 23% higher (95% CI = −4%–59%) and mortality was 15% higher (95% CI = −30%–89%) compared with those not receiving it (n = 14 573). Neither agent had any effect on the time interval between diagnosis and death. Conclusions: Long-term supplementation with a-tocopherol substantially reduced prostate cancer incidence and mortality in male smokers. Other controlled trials are required to confirm the findings. [J Natl Cancer Inst 1998;90:440–6]
The widespread Indo-Pacific Slender Gecko Hemiphyllodactylus typus: a single species across the Oceans ?

The Indo-Pacific Slender Gecko Hemiphyllodactylus typus is distributed across the Indian and Pacific Oceans. Its ecological flexibility and vast distribution may raise concerns of a potential invasion in tropical and subtropical islands worldwide, but evidence of a recent spread is lacking. The identity of the species has also been questioned across its distribution range. In this note we synthesise information obtained from the literature on the distribution and the habitat use of the species. We stress the need to develop new sampling techniques to improve its detection, and perform phylogenetic analyses to formally identify the species across the different regions and determine its colonisation history.
CONSTANS-LIKE 7 (COL7) Is Involved in Phytochrome B (phyB)-Mediated Light-Quality Regulation of Auxin Homeostasis

Arabidopsis phytochrome B (phyB) is the major photoreceptor that senses the ratio of red to far-red light (R:FR) to regulate the shade-avoidance response (SAR). It has been hypothesized that altered homeostasis of phytohormones such as auxin and strigolactone is at least partially responsible for SAR, but the mechanism underlying phyB regulation of the hormonal change is not fully understood. Previously we reported that CONSTANS-LIKE 7 (COL7) enhances branching number under high R:FR but not under low R:FR, implying that COL7 may be involved in the phyB-mediated SAR. In this study, we provide evidence that COL7 reduces auxin levels in a high R:FR-dependent manner. We found that the phyB mutation suppresses the COL7-induced branching proliferation. Moreover, COL7 promotes mRNA expression of SUPERROOT 2 (SUR2), which encodes a suppressor of auxin biosynthesis, in high R:FR but not in low R:FR. Consistently with these results, deficiency of phyB suppresses the elevated transcription of SUR2 in COL7 overexpression plants grown in high R:FR. Taking these results together with data suggesting that photo-excited phyB is required for stabilization of the COL7 protein, we argue that COL7 is a critical factor linking light perception to changes in auxin level in Arabidopsis.
Molar Absorptivities of f3-NADH and /3-NAD at 260 nm

To determine the molar absorptivities of /3-NADH and fl-NAD at 260 nm, we purified the reduced form of the coenzyme by repeated anion-exchange chromatography. A NADH preparation was so obtained for which the 260 nm/340 nm absorbance ratio was 2.265. When calculated with = 6.22 X iO for f3-NADH at 260 nm and 25 #{176}C, a molar absorptivity of 14.1 X i0 liter#{149} mor’ cm resulted from this quotient. By use of the lactate dehydrogenase or glycerol-3-phosphate dehydrogenase assay, respectively, and referring to the new absorption coefficient for NADH at 260 nm, the molar absorptivity of -NAD at 260 nm and 25 #{176}C was established to be 17.4 X iO liter#{149} mor cm. The values observed are lower than those reported thus far.
A note on Gromov-Hausdorff-Prokhorov distance between (locally) compact measure spaces

We present an extension of the Gromov-Hausdorff metric on the set of compact metric spaces: the Gromov-Hausdorff-Prokhorov metric on the set of compact metric spaces endowed with a finite measure. We then extend it to the non-compact case by describing a metric on the set of rooted complete locally compact length spaces endowed with a locally finite measure. We prove that this space with the extended Gromov-Hausdorff-Prokhorov metric is a Polish space. This generalization is needed to define Lévy trees, which are (possibly unbounded) random real trees endowed with a locally finite measure.
OP-NCON200018 1..16

The subjective features of psychological phenomena have been studied intensively in experimental science in recent years. Although various methods have been proposed to identify subjective features of psychological phenomena, there are elusive subjective features such as the spatiotemporal structure of experience, which are difficult to capture without some additional methodological tools. We propose a new experimental method to address this challenge, which we call the contrastbased experimental phenomenological method (CEP). CEP proceeds in four steps: (i) front-loading phenomenology, (ii) online second-personal interview, (iii) questionnaire survey, and (iv) hypotheses testing. It differs from other experimental phenomenological methods in that it takes advantage of phenomenal contrasts in collecting phenomenological data. In this paper, we verify the validity and productivity of this method by applying it to binocular rivalry (BR). The study contributes to empirical research on BR in three respects. First, it provides additional evidence for existing propositions about the subjective features of BR: e.g. the proposition that the temporal dynamics of the experience depend upon subject-dependent Received: 26 July 2019; Revised: 20 April 2020. Accepted: 9 June 2020 VC The Author(s) 2020. Published by Oxford University Press. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. 1 Neuroscience of Consciousness, 2020, 6(1): niaa018 doi: 10.1093/nc/niaa018