Miracle-dz/UniFAR-FTUs huggingface dataset:
Perceptions of professionals on neonatal pain: a descriptive study

Objetivo: conhecer as percepcoes dos profissionais de saude sobre a terapia intensiva neonatal. Metodo: estudo exploratorio, descritivo, qualitativo, realizado de um ano de 2013 com 10 enfermeiros, 40 tecnicos de enfermagem, dois fisioterapeutas e seis residentes de Enfermagem de uma Maternidade Escola do Rio de Janeiro. A tecnica de coleta de dados foi uma intervencao educacional, enquanto que as falas foram transcritas e submetidas a analise de conteudo tematica. Resultados: emergiram tres categorias: "Identificando e avaliando a dor do recem-nascido nas situacoes dolorosas"; "Promovendo o manejo nao farmacologico da dor"; "Identificando como barreiras para o manejo da dor na Unidade Neonatal". Conclusao: na percepcao dos profissionais, a existencia e a presenca dos presentes estao presentes em seu cotidiano, portanto, o conhecimento sobre a tematica ainda esta envolvido e precisa ser aprofundado para que exista uma aplicacao na pratica clinica assistencial .
Serum Vitamin C Concentration Was Inversely Associated With Subsequent 20-Year Incidence of Stroke in a Japanese Rural Community

Background and Purpose—Epidemiological evidence suggests that vitamin C may decrease the risk of stroke. The purpose of the present study was to examine the association of serum vitamin C concentration with the subsequent incidence of stroke. Methods—In a Japanese rural community, a cohort of 880 men and 1241 women aged 40 years and older who were initially free of stroke was examined in 1977 and followed until 1997. The baseline examination included a measurement of serum vitamin C concentration. The incidence of stroke was determined by annual follow-up examinations and registry. Results—During the 20-year observation period, 196 incident cases of all stroke, including 109 cerebral infarctions and 54 hemorrhagic strokes, were documented. Strong inverse associations were observed between serum vitamin C concentration and all stroke (sex- and age-adjusted hazard ratios were 0.93, 0.72, and 0.59, respectively, for the second, third, and fourth quartiles compared with the first quartile; P for trend=0.002),.
Conceptualization and Multi-Objective Analysis of Multi-Cell Solid-State Transformers

I the share of renewable energy sources in the total energy production as well as improving the energy efficiency in general are important goals ranking high on political agendas, and are aiming at a reduction of greenhouse gas emissions and a sustainable usage of limited resources. Solid-state transformers (SSTs), which are galvanically isolated power electronic conversion interfaces between a medium-voltage (MV) system and a low-voltage (LV) system, whereby the isolation transformer is operated in the mediumfrequency (MF) range, can contribute to achieving these goals in two different ways: SSTs are envisioned for replacing conventional low-frequency (LF) transformers (LFTs) in applications such as traction, where weight and volume savings as well as efficiency improvements can be achieved, or, utilizing the controllability inherent to power electronic systems, in smart distribution grids in order to address, e. g. , the challenges arising from an increased amount of renewable energy sources connected at lower voltage levels. There are five main classes of modern SST topologies: matrix-type ACAC topologies, isolated back end (IBE) topologies, isolated front end (IFE) topologies, topologies based on the modular multilevel converter (M2LC), and single-cell topologies based on novel silicon carbide (SiC) power devices with very high blocking voltages. However, because of the limited blocking voltage capability of readily available power semiconductors, typically multicell converter structures are employed to cope with high voltages. Therefore, considering the cascaded AC-DC input stage of a typical multicell IBE SST, i. e. , a generic cascaded H-bridge converter structure, a comprehensive analysis and a multi-objective optimization of the optimum number of cascaded converter cells (or equivalently, the optimum blocking voltage of the employed silicon (Si) power semiconductors) is provided, which is based on physics-inspired, empirical models of the dependencies of Si power semiconductors’ loss-relevant parameters on the rated blocking voltage and current. For a 1MVA system connected to the 10 kV grid, designs based on 1200V or 1700V devices (corresponding to 15 or 11 cascaded full-bridge cells per phase stack, respectively) are identified as providing the most suitable trade-offs between efficiency (above 99%) and power density (about 5 kW/dm3). Significant efficiency and power density gains can be realized by replacing Si IGBTs with LV SiC devices in multi-cell systems, whereas single-cell designs based on high-voltage SiC devices suffer from the high dv/dt and di/dt values required to limit switching losses. Furthermore, the reliability of multi-cell SST systems is analyzed, and it is shown that cell redundancy, which is facilitated by the modular nature of vii
Determination and distribution of various antinuclear antibodies in systemic lupus erythematosus patients by using immunoblot testing

Background: Systemic lupus erythematosus (SLE) is defined as a multisystemic inflammation resulting from production autoantibodies against nuclear and cytoplasmic antigen. Objective: The present study was undertaken to determine the distribution of various auto antibodies in SLE patients by line immuno assay. Materials and methods: A prospective study conducted at Yashodha Hospital, Somajuguda, Hyderabad. A total number of 120 clinically diagnosed SLE patients serum samples were collected and they were subjected to indirect immunofluorescence testing (IIFT) to screen autoantibodies. results: Out of 120 patients 97 were males and 23 were females, predominant age group affected was 4160 years. Out of 120 patients 99 were positive by IIFT. Predominant pattern in IIFT is nucleus homogenous (54.54%), followed by nucleus speckled (29.9%). Out of 120 patients 69 were positive by ANA immunoblot, in that the predominant autoantibody was anti dsDNA antibody (40.57%), followed by RO-52 (31.88%), SSA (30.43%). Out of 120 Samples 68 were positive by both IIFT and immunoblot, 31 were only positive by IIFT, 20 were negative by both and one was only positive by immunoblot. conclusion: The study stresses on using IIFT as screening test for SLE. It should be followed by ANA immunoblot to determine specific antibody, which inturn helps in diagnosis, evaluation and follow-up of SLE patient.
New feeding networks and planar antenna designs for leaky-wave systems and communication applications

The fast development in modern communication systems such as radars, medical imaging, sensors or satellites demands efficient and compact antenna designs that can satisfy the high data throughput and beam scanning requirements. This is commonly achieved by different means including electromechanical or mechanical steering, which sometimes are not the best option as additional cost, size or losses may be introduced. However, low-cost and compact structures can be obtained by using planar leaky-wave antennas, whose inherent high directivity and electrical beam steering capabilities have been realised to be a solution for the issues encountered by these systems. Nevertheless, there are several limitations that these antennas still need to overcome. One clear example is the lack of efficient and simple feeding networks for certain types of leaky-wave antennas that can reduce their performance and compactness. In turn, there are modern indoor applications, such as WiFi or radio frequency identification (RFID), where selective distributed communications are required but current leaky-wave antennas cannot efficiently provide or their use implies cost and weight constraints. In this thesis, planar configurations are presented to provide efficient and low profile solutions for leaky-wave antennas using concepts such as partial reflective surfaces or simple technologies as parallel-plate waveguides. It is also demonstrated that novel systems for two-dimensional (2D) or wideband beam scanning can also be obtained by the use of simple feeders including vertical electric dipoles. In addition, a broad-beam alternative to a non-selective and expensive beam scanning performance inside airplanes for RFID systems is introduced easing weight restrictions. These configurations represent an advancement for the state-of-the-art and are interesting alternatives to their non-planar counterparts. To support these designs, theoretical analysis, full-wave simulations and measurements are provided.
A Novel Biomarker Renalase and Its Relationship with its Substrates in Schizophrenia

Summary Background Schizophrenia, particularly the form related to excessive dopamine (DA), is a chronic psychotic disorder affecting millions of people worldwide. Renalase metabolizes its catecholamine (CA) substrates, including DA, suggesting that there might be an association between renalase levels and schizophrenia occurrence. Therefore, the current study aimed to evaluate the renalase and CA levels in the serum of patients with schizophrenia. Methods The study was conducted with thirty-three schizophrenia patients and an age- and gender-matched group of thirty-one controls. Renalase and CA levels were measured by using an enzyme-linked immunosorbent assay (ELISA). Results Renalase levels were significantly lower in the schizophrenia patients than in the control group (p<0.05), whereas DA levels were significantly higher (p<0.05). The epinephrine (Epi) levels of both groups were similar (p=0.186), while the norepinephrine levels in patients with schizophrenia were significantly lower than those in the control group (p<0.05). The areas under the curves for the renalase-dopamine, renalase-norepinephrine and renalase-epinephrine ratios were 0.805, 95% confidence interval (CI): 0.699–0.912 (p<0.001); 0.726, 95% CI: 0.594–0.859 (p=0.032); and 0.656, 95% CI: 0.520–0.791 (p=0.02). Conclusions The high DA levels in patients with schizophrenia might be due to low renalase levels. Renalase enzyme levels may play a substantial role in the pathophysiology of schizophrenia. Thus, this enzyme might be a new future target for the treatment and diagnosis of schizophrenia after intrabrain renalase and DA dynamics have been further evaluated.
TAXONOMÍA, DISTRIBUCIÓN GEOGRÁFICA E HISTORIA NATURAL DEL ENDEMISMO IBÉRICO GLUVIA DORSALIS (LATREILLE, 1817) (SOLIFUGAE: DAESIIDAE)

Gluvia dorsalis (Latreille, 1817), an Iberian endemic belonging to a monospecific genus, is, so far, the only Solifugae known from this area. In this study the morphological variability of the species is described according to present terminology, with the addition of new findings about its life cycle, habitat and ecology and an update on bibliography and chorology of the taxon. Accordingly, in view of its peculiarity, a higher level of protection is recommended for the species.
Linking Ecosystem Services to Land Use Decisions: Policy Analyses, Multi-Scenarios, and Integrated Modelling

Rapid industrialization and urbanization have brought dramatic changes to land use structure and layout but have caused several negative impacts on the ecosystem and environment. Increasing the supply of ecosystem services (ESs) in important ecological regions through land use optimization is one strategy that must be seriously considered in land use planning. However, existing land use optimization primarily focuses on economic outcomes, and is difficult to adapt to the practical needs of ecological civilization construction in China. Therefore, we formulated a framework that links ESs to land use decisions by combining policy analyses, multi-scenarios and integrated modelling. The paper is organized into three main parts. First, we conduct a systematic literature review to land use change (LUCC), ESs, and their relationship. Next, we build on insights from the literature review to develop a conceptual framework that integrates ESs into land use optimization. The framework includes a quantitative analysis and spatial allocation of land use. For the quantitative analysis, in addition to considering the development trends, we set ESs to achieve national requirements. Then, an optimized scenario targeted at the maximum ecosystem service value was built. For the spatial allocation, we combined multi-layer perception (MLP) and cellular automaton (CA) and developed an MLP-CA model independently. Last, an empirical study of the proposed framework was implemented in Puge County, China. Our results provide a new technical tool for the layout of optimal land use under the constraint of ecological protection policies and provides a way to address trade-offs between ecological, social, and economic values.
Dental Perspective on Biomedical Waste and Management, a Knowledge, Attitude and Practice Survey: A Cross-sectional Study

Background: The biomedical waste is known as the second dangerous waste in the world that needs to be properly managed. Since the implementation of the Biomedical Waste Management (BMW) Rules, 1998, every concerned health personnel is expected to have proper knowledge, practice, and capacity to guide others for waste collection and management, and proper handling techniques. Aims and Objectives: The present study was planned to evaluate the practical calibration and awareness of dental surgeons in disposal of hazardous biomedical waste generated during dental treatment into color-coded disposing bags at a dental clinic. Materials and Methods: A cross-sectional, a pre-tested, semi-structured questionnaire-based survey containing 53 questions to assess the knowledge, attitude, and practice on BMW among dental surgeons was planned. Results were expressed as a number and percentage of respondents for each question and Chi-square test was performed for inferential statistical analysis with P<0.05 indicating level of statistical significance. Results: Results showed that a large percentage of the dentist was not aware of the process of BMW (89%), whereas about half of the subjects were moderate to slightly aware of the recycling/ reusing of dental materials. Conclusion: The study revealed that knowledge, attitude, and practice regarding BMW among were low. Periodical sensitization and training program should be conducted for health-care providers.
Impact of Land Use Types and Seasonal Variations on Soil Physico-chemical Properties and Microbial Biomass Dynamics in a Tropical Climate, Ghana

Land use conversion significantly impact on sensitive soil quality parameters such as microbial biomass and soil microbial quotient. Therefore, soil microbial biomass and physicochemical properties were compared under three different land use systems namely agricultural land, degraded mine land and an adjacent natural forest in the Newmont Gold Ghana Limited Original Research Article Agbeshie et al.; AIR, 21(1): 34-49, 2020; Article no.AIR. 54727 35 concessional areas, Kenyasi, Ghana. In our field experimentation, an area of 300 m was demarcated in each land use type for soil sampling. In each of the land use type, we collected soil 5 samples at a depth of 0-15 cm in both the dry and wet seasons respectively. Parameters we measured included soil bulk density, pH, particle size distribution, organic carbon, total nitrogen, available phosphorus, microbial biomass carbon and nitrogen, and moisture content. Our results revealed that land use type significantly impacted on soil microbial biomass and physicochemical properties. Microbial biomass carbon and nitrogen was higher in the forested land compared to the agricultural land and degraded mine land, which was due to relatively higher amounts of litter inputs. Microbial biomass carbon decreased between 20.23 88.36% when land use changed from forested land to other land uses. Significant positive correlation was observed between soil microbial biomass and water content, soil organic carbon, phosphorus, clay, nitrogen. Generally, seasonal variation in our study area did not influence soil physical and chemical properties, however, it significantly affected microbial biomass indices. Findings of our study further revealed the importance of forested area in the maintenance of soil quality parameters.
Serial Ingestion or Co-ingestion of Creatine and Sodium Bicarbonate on Performance Following a Resistance Exercise Workout: A Pilot Study

To examine the ergogenic potential of creatine (Cr), sodium bicarbonate (SB), and Cr+SB after completion of a resistance exercise bout (REB). Methods: Following recruitment, 27 trained males (26.8±5.7 y) completed a one repetition maximum (1RM) strength test in the parallel squat (120.9±28.2 kg). Participants then followed a standardised meal plan for four days whilst ingesting one of four supplements, and on day five they undertook the REB. This was a double blind randomised placebocontrolled study where participants ingested one of the following: Placebo (PLA, n=7), Cr (20 g . d -1 and PLA, n=8), SB (0.5 g . kg -1. d -1 and PLA, n=6), and Cr+SB (5 g . d -1
Dignity of risk in the community: a review of and reflections on the literature

Taking risks is a part of everyday living, and a contributor to our sense of dignity. Yet as people age, or develop cognitive, mental or physical impairments, opportunities to take risks can diminish. A life without risks can erode a person’s dignity. The purpose of this narrative review was to explore the application of the concepts of the Dignity of Risk and Therapeutic Risk in literature pertaining to community-based support for people living with a range of physical, mental and/or cognitive constraints. We aimed to understand how these concepts are conceptualised, articulated, negotiated and enacted in theory and practice. During a period from October 2017 to January 2018, seven databases were searched for relevant literature. Thematic analysis techniques were applied to synthesise the data from 47 academic papers that met the inclusion criteria. Our analysis demonstrates persistent ethical tensions. There is widespread support for the application of both concepts across a range of discourses, but a number of long-standing ethical considerations pertaining to risk, safety, rights and negotiation persist. We argue that the way forward is to resist the temptation to simplify the issues, but instead to accept and accommodate ethical complexities while implementing evidence-informed solutions such as intersubjective risk negotiation strategies, community-centred relational approaches to decision-making, and education and training in communication skills and the positive potential of risk. Future research to examine the impacts of the implementation of these strategies would be timely, beneficial and welcome.
Correlations and Differences in Glomerular Filtration Rates Calculated Through In-House and Non-In-House Workstations of Scintigraphic Gamma Cameras

Background: Technetium-99m diethylene triaminepentaacetic acid (Tc-99m DTPA) renal scintigraphy using modified Gate’s method is commonly adopted to calculate glomerular filtration rate (GFR). Objectives: The purpose of this study was to find the correlations between GFRs, which are calculated by the in-house and non-inhouse workstations from gamma cameras (GC) manufactured by different firms. Patients and Methods: Medical records of patients receiving Tc-99m DTPA renal scan between January and December 2016 were analyzed. Patients were allocated randomly to a GC (1 or 2). The calculated GFRs were conducted by the in-house workstation (group A: workstation 1/ GC 1; group B: workstation2/ GC 2) and the non-in-house workstation from the GC (group C: workstation 2/ GC 1; group D: workstation 1/ GC 2). All patients had their creatinine levels checked to calculate the estimated GRF (eGFR) as the reference data. Comparison of correlation and difference between GFR calculations (group A, B, C and D), eGFRs and clinical parameters was analyzed. Results: Forty patients (24 men, 16 women) were enrolled in this study. The average of eGFRs was 63.0 ± 38.5 mL/min/1.73m. The GFRs (group A to D) calculated were all significantly correlated with the eGFR. However, there was a significant difference between group C and eGFR (P = 0.0021), and group D and eGFR (P = 0.0262). Eight patients (20%) had changed stage of chronic kidney disease when using non-in-house workstations, compared to in-house workstations from GC. Conclusion: GFRs calculated by the non-in-house workstation were significantly different from eGFR. Use of workstation and GC from the same manufacturer would provide more accurate data in the clinical setting.
Advantages and Limitations in the Use of Combination Therapies with Charged Particle Radiation Therapy.

Purpose Studies are currently underway to help provide basic and clinical evidence for combination particle beam radiation therapy, on which there are few published reports. The purpose of this article is to summarize the current status in the use of particle beams combined with other modalities. Results Following from experiences in x-ray radiation therapy, combination therapy with proton beams (PBT) has been attempted, and several clinical studies have reported improved survival rates for patients with non-small cell lung cancer, pancreatic cancers, esophageal cancers, and glioblastomas. Recently, basic studies combining PBT with PARP inhibitors and histone deacetylase inhibitors have also reported promising results. In the area of carbon ion therapy (CIT), there are few clinical reports on combination therapy; however, the number of basic research reports exceeds that for PBT. So far, the combined use of cytotoxic drugs with CIT yields independent additive effects. In addition, it is notable that combination therapy with CIT is effective against radioresistant cancer stem-like cells. Recent evidence also suggests that local radiation therapy can induce an effective antitumor immune response. There has been an increased use of combination immune-modulating agents and cytokines with particle beams, especially CIT. The field of radiation therapy is evolving from a strong reliance on local-regional treatment to a growing reliance on systemic immunotherapy. Conclusions The combined use of anticancer agents with particle radiation therapy has a considerable potential effect. Future research in molecular targeting therapy and immunotherapy may help identify the most efficacious approach for combination therapy with protons and carbon ions.
An Empirical Survey of Autonomous Scheduling Methods for TSCH

Time Slotted Channel Hopping (TSCH) is a link layer protocol defined in the IEEE 802.15. 4 standard. Although it is designed to provide highly reliable and efficient service targeting industrial automation systems, scheduling TSCH transmissions in the time and frequency dimensions is left to the implementers. We evaluate the performance of existing autonomous scheduling approaches for TSCH on various traffic patterns and network configurations. We thoroughly investigate the pros and cons of each scheme; moreover, we propose the use of node based channel allocation to improve the performance of the best scheme, and demonstrate its practicality and reliability, with up to 6 percentage points better packet delivery ratio than the second best option while retaining a similar radio duty cycle. Finally, based on our extensive performance evaluation, we provide some guidelines on how to select a scheduler for a given network.