Miracle-dz/UniFAR-FTUs huggingface dataset:
Stereotactic and Robotic Minimally Invasive Thermal Ablation of Malignant Liver Tumors: A Systematic Review and Meta-Analysis

Background Stereotactic navigation techniques aim to enhance treatment precision and safety in minimally invasive thermal ablation of liver tumors. We qualitatively reviewed and quantitatively summarized the available literature on procedural and clinical outcomes after stereotactic navigated ablation of malignant liver tumors. Methods A systematic literature search was performed on procedural and clinical outcomes when using stereotactic or robotic navigation for laparoscopic or percutaneous thermal ablation. The online databases Medline, Embase, and Cochrane Library were searched. Endpoints included targeting accuracy, procedural efficiency, and treatment efficacy outcomes. Meta-analysis including subgroup analyses was performed. Results Thirty-four studies (two randomized controlled trials, three prospective cohort studies, 29 case series) were qualitatively analyzed, and 22 studies were included for meta-analysis. Weighted average lateral targeting error was 3.7 mm (CI 3.2, 4.2), with all four comparative studies showing enhanced targeting accuracy compared to free-hand targeting. Weighted average overall complications, major complications, and mortality were 11.4% (6.7, 16.1), 3.4% (2.1, 5.1), and 0.8% (0.5, 1.3). Pooled estimates of primary technique efficacy were 94% (89, 97) if assessed at 1–6 weeks and 90% (87, 93) if assessed at 6–12 weeks post ablation, with remaining between-study heterogeneity. Primary technique efficacy was significantly enhanced in stereotactic vs. free-hand targeting, with odds ratio (OR) of 1.9 (1.2, 3.2) (n = 6 studies). Conclusions Advances in stereotactic navigation technologies allow highly precise and safe tumor targeting, leading to enhanced primary treatment efficacy. The use of varying definitions and terminology of safety and efficacy limits comparability among studies, highlighting the crucial need for further standardization of follow-up definitions.
Impact of a single school-based intervention for COVID-19 on improving mental health among Japanese children

An underlying concern about the COVID-19 pandemic is the decline of children’s mental health. The present study is aimed to investigate whether a single school-based intervention, including self-monitoring and psychoeducation for COVID-19, effectively achieved its aim to promote children’s mental health. The study was conducted in a junior high school. We assigned the third grade as the intervention group, the second grade as the announcement group, and the first grade as the control group. We hypothesized that the intervention group would experience improved mental health and reduced fear of COVID-19 compared to the announcement and control groups. Interaction effects were observed only for depression, indicating a significant effect in the intervention group. These findings suggest that a single school-based intervention that includes self-monitoring and psychoeducation for COVID-19 can help improve children’s mental health. It is suggested that school-based interventions that intend to raise children’s awareness of COVID-19 promote their healthy development and adaptation to crises within the school.
Synthesis, structural and magnetic properties of Nixco1-xFe2O4 and Co(RE)0:1Fe1:9o4 nano-ferrites.

NixCo1−xFe2O4 (x = 0 to 1 incremented by 0.1) nanoferrites were prepared by the glycol-thermal technique at 200 ◦C. Formation of single phase cubic spinel structure was confirmed by X-ray diffraction (XRD) data for nearly all the compounds, except x = 0.7 to 0.9 which had small impurity phases that were suspected to be due to NiFe formation. The particle or crystallite sizes range from about 8 nm to 14 nm across the composition range. Fe Mössbauer spectra measured from 80 K to room temperature were fitted with two sextets and one doublet. We associate the sextets and doublet with magnetically ordered and paramagnetic state Fe ions respectively. Paramagnetic state is observed for x = 0.7 to 0.9 at room temperature. At 80 K, the hyperfine fields and isomer shifts are more enhanced which demonstrate an increased magnetic ordered. The hyperfine fields for the sample x = 0.1 decrease from about 536 kOe at 80 K to 0 kOe at 483 K. A total collapse in magnetic order occurs at about 478 K. Room temperature magnetization measurements performed on a vibrating sample magnetometer (VSM) show a reduction in coercive fields with increased x due to smaller anisotropy of Ni than Co. Energy dispersive X-ray (EDX) analysis confirmed the stoichiometric presence of Ni, Co and Fe atoms on the samples x = 0.3 and 0.5 which were further annealed up to 1100 ◦C. High resolution transmission electron microscopy (HRTEM) data confirmed the XRD results which show increasing cryatallite sizes from about 13 nm to 110 nm after annealing at 1100 ◦C. Mössbauer spectra revealed a general increase in hyperfine fields with increasing crystallite size which is attributed to stronger superexchange interactions as a result of enhanced particle size. Higher coercivity for larger particles indicates transition from single to multi-domain structure. Co(RE)0.1Fe1. 9O4 (RE = Ce, Nd, Sm, Gd, Dy, Er and Yb) nanoferrites were also synthesized by the glycolthermal technique. Single phase formation was confirmed by XRD data which also revealed crystallite sizes between 8 nm and 14 nm. A decrease in the hyperfine fields and coercivity is observed on substitution of the magnetic Fe ions, in CoFe2O4, with the non-magnetic RE ions which is expected. This study has shown strong correlation between coercivity and particle sizes with sample preparation pressure which demonstrates a strong connection between the magnetic properties, crystallite
Kinetics and thermodynamics of water extraction of foxtail millet polysaccharides

In order to understand the mechanism of the extraction process of polysaccharides from foxtail millet by hot water, the extraction was carried out for studying the kinetics and thermodynamics of extraction process. After the appropriate stirring rate and liquid material ratio was selected through preliminary experiment, the changes of polysaccharides mass concentration in the extract liquor with extraction temperature and extraction time were measured. The experimental data were fitted by the first-order model. The kinetics and thermodynamics parameters were calculated. The results showed that the appropriate stirring rate and liquid material ratio was 150 r/min, 20.0 mL/g respectively. The greater extraction rate and higher equilibrium mass concentration could be obtained under higher extraction temperature. The extraction process accorded with the first-order dynamics model. The apparent activation energy of process was 12.03 kJ/mol under study conditions. The internal diffusion coefficient was increased with increasing temperature in the range of 7.84×10-10 - 1.29×10-9 m2/min. The half-life was decreased from 25.2 min to 3.9 min as temperature increased. The Gibbs free energies were all less than zero, the enthalpy change was 31.96 kJ/mol and the entropy change was 120.3 J/(mol·K) in process. The polysaccharides extraction process was a spontaneous, endothermic and entropy increases process.
Primary Bladder Adenocarcinoma: A Case Report

Primary bladder adenocarcinoma (PBA) is rarely seen in the clinical setting at present. Bladder adenocarcinoma has a special biological behavior, as well as high invasive and metastatic potential. In addition, it is very difficult to diagnose PBA at an early stage. Having similar clinical manifestation to urothelial carcinoma and metastatic adenocarcinoma of the bladder, the differential identification and diagnosis have become more complicated. A majority of adenocarcinoma is not sensitive to radiation and chemotherapy, and thus, the prognosis of PBA is generally poorer. Currently, surgery serves as the principal mode of treatment. In this case report, we had observed a PBA case for 1.5 years, and no recurrence and metastasis had been reported.
New Insights on the Energy Impacts of Telework in Canada

Quantifier l’impact du télétravail sur la consommation d’énergie a longtemps été difficile en raison du faible recours au télétravail. La pandémie de la COVID-19 et le passage généralisé au télétravail fournit une nouvelle occasion pour étudier l’impact du télétravail sur la consommation d’énergie. Dans les deux mois qui ont suivi les confinements, nous avons interrogé 278 travailleurs ayant des emplois fondés sur le savoir qui ont commencé à travailler principalement de chez eux, afin d’étudier leurs comportements et attitudes quant à la consommation d’énergie. Les thèmes principaux de l’enquête sont les actions prises au travail visant la réduction de consommation d’énergie, l’équipement utilisé pour le télétravail, l’impact sur la consommation résidentielle, et la prise de conscience et la réaction quant au prix de l’électricité. Étant donné la tendance plus accrue au télétravail à l’avenir, ces résultats peuvent éclairer la politique publique en matière de télétravail et d’énergie.
Association of attention and memory biases for negative stimuli with post-traumatic stress disorder symptoms.

Cognitive models have highlighted the role of attentional and memory biases towards negatively-valenced emotional stimuli in the maintenance of post-traumatic stress disorder (PTSD). However, previous research has focused mainly on attentional biases towards distracting (task-irrelevant) negative stimuli. Furthermore, attentional and memory biases have been examined in isolation and the links between them remain underexplored. We manipulated attention during encoding of trauma-unrelated negative and neutral words and examined the differential relationship of their encoding and recall with PTSD symptoms. Responders to the World Trade Center disaster (N = 392) performed tasks in which they read negative and neutral words and reported the color of another set of such words. Subsequently, participants used word stems to aid retrieval of words shown earlier. PTSD symptoms were associated with slower response times for negative versus neutral words in the word-reading task (r = 0.170) but not color-naming task. Furthermore, greater PTSD symptom severity was associated with more accurate recall of negative versus neutral words, irrespective of whether words were encoded during word-reading or color-naming tasks (F = 4.11, p = 0.044, ηp2 = 0.018). Our results show that PTSD symptoms in a trauma-exposed population are related to encoding of trauma-unrelated negative versus neutral stimuli only when attention was voluntarily directed towards the emotional aspects of the stimuli and to subsequent recall of negative stimuli, irrespective of attention during encoding.
Intentions to comply with COVID-19 preventive behaviors are associated with personal beliefs, independent of perceived social norms

Social norms can be an effective way to promote public health and encourage healthy behaviors among individuals. The global COVID-19 pandemic has prompted health officials to call for new behavioral norms to help prevent the disease’s spread, for example “social distancing” measures. Yet whether people actually intend to engage in these behaviors (behavioral intention) may depend on both whether they personally find them effective (individual beliefs), and whether they think others will engage in them too (perceived norms). In this study we tested three hypotheses on the relationships between individual beliefs, perceived norms, and behavioral intentions related to COVID-19 preventive health behaviors. We predicted: H1) that perceptions of others’ beliefs about the importance and impact of preventive behaviors (perceived norms) would be lower than individuals’ own beliefs (i.e., a pluralistic ignorance effect); H2) that perceived norms and individual beliefs would each predict behavioral intentions; and H3) that the difference between perceived norms and individual beliefs would uniquely predict behavioral intentions. We observed large self-other differences in beliefs about preventive health behaviors (support for H1). However, only individuals' own beliefs were associated with behavioral intention, not perceived norms or the self-other gap (no support for H2 or H3). In short, individuals did not differ in their preventive behavioral intentions based on the differences (or their lack thereof) between perceived social norms and their personal beliefs. Participants who strongly believed that preventive behaviors are important ignored normative pressures from average Americans, who they perceived as less concerned than themselves. Together, these findings highlight the different roles personal beliefs and perceived norms might play in forming behavioral intentions.
Salt response in pepper (Capsicum annuum L.): components of photosynthesis inhibition, proline accumulation and K+/Na+ selectivity

Three salinity of irrigation water (control, 70, 120 and 170 mM NaCl) were applied to five cultivars of hot pepper ( Capsicum annuum L.) collected from the South of Tunisia. After three weeks, relative water content, photosynthetic pigment levels, gas exchange, proline, soluble sugars and ions K + and Na + concentrations were measured. The results showed that the inhibition of photosynthesis was not mainly stomatal, but probably biochemical manifesting by a stability of stomatal conductance up to 120 mM NaCl and accompanied by a continuous increase in intercellular CO 2 concentration under the three concentrations of salt. Proline content increased considerably as a result of stress and reaches almost double those of controls in cultivars Alaya, Shkira and Sgay and even triple in cultivars Maghraoua and Farch. Solubles sugars do not contribute effectively to the osmotic adjustment. Mineral analysis showed that until 120 mM NaCl, the highest concentration of Na + was obtained in stems, probably reflecting the existence of a re-circulation mechanism of Na + . Meanwhile, salinity reduced the foliar K + content. At stems level, K + concentration does not show significantly disruptions compared to control. However, at the roots, there is a continuous increase in potassium content. For K + /Na + shoot ratio and at 70 mM NaCl, all cultivars showed a decrease of selectivity except cv. Maghraoua. At 120 and 170 mM, the same cultivar showed the lowest reduction. In root system, at 70 mM NaCl, cv. Maghraoua showed the greater improvement of selectivity.
Persepsi dan Pengambilan Keputusan Milenial Terhadap Instrumen Investasi Masa Depan

Penelitian ini bertujuan untuk mengetahui persepsi dan pengambilan keputusan yang diambil oleh kaum milenial dalam memilih instrument-intrumen yang digunakan dalam investasi untuk merencnakan keuangan di masa mendatang dan memberikan pemahaman serta penjelasan mengenai Instumen atau bentuk-bentuk dari investasi Saat ini yang lebih praktis untuk digunakan. teknologi dan pemikiran manusia semakin maju seiring dengan perkembangan zaman yang cepat dan dinamis banyak instumen investasi baru yang bermunculan yang lebih modern dan mengadopsi media digital pada penelitian ini menggunakan metode studi literatur yang berasal dari berbagai sumber seperti buku, jurnal dan website, dari penelitian mendapatkan hasil bahwa banyak kaum milenial yang berinvestasi dengan media yang memiliki resiko yang rendah seperti Emas, deposito, properti dan reksadana berikut ini presentase yang didapat dari penelitian menggunakan studi literatur setangah dari responden yanga dan memiliki investasi berupa emas. Investasi lain yang dimiliki masyarakat adalah deposito sebesar 37%, property 30%, reksadana 22%, dan saham sebesar 17%.
Statistical Analysis of Breast Cancer Cases in University College Hospital (UCH) Ibadan, Nigeria

Breast cancer is a significant cause of cancerrelated mortality in women all over the world (Agboola et al., 2012). The incidence of breast cancer in women is rising across the globe (GLOBOCAN, 2012). A comparison of the World Health Organization’s International Agency for Research On Cancer [IARC], latest two versions (GLOBOCAN, 2008 & 2012) showed that the number of new cases increased from 12.7 million in 2008 to 14.1 million cases in 2012. Approximately 1.4 million women were diagnosed with breast cancer in 2012. There are 6.3 million women alive who have been diagnosed in the previous five years (Ferlay et al., 2010). Since the 2008 estimates, breast cancer incidence has increased by more than 20% while mortality has increased by 14%.
Social Distancing Around the Globe: Cultural Correlates of Reduced Mobility

Background: While the United States has struggled to keep the spread of COVID-19 at bay, many other countries have significantly stunted the number of new cases. Recent evidence suggests that cultural factors may play a key role in the spread of infection. To examine the cultural values underlying adherence to social distancing, this study used global cultural data as well as mobility scores from Google LLC’s global measurement on mobility. Methods: A composite variable for country-level engagement in social distancing was created from February 15, 2020 to June 7, 2020 (N = 14,022) across 118 countries. Segmented piece-wise multilevel modeling was used to examine the influence of cultural values of uncertainty avoidance, individualism-collectivism, tightness-looseness, and societal level of trust in three distinct time frames: 1) from February 15, 2020 to the country’s 100th COVID-19 case, 2) the first 30 days after each country’s 100th COVID-19 case, and 3) from the 31st day after the 100th case to June 7, 2020. Results: Results showed that collectivism promoted quick mobilization of social distancing behaviors while uncertainty avoidance stunted this mobilization. After the 100th case of COVID-19, high societal level of trust was related to the decline of social distancing behaviors. Interaction effects showed that countries high on uncertainty avoidance, collectivism, and tightness were all quicker to engage in social distancing at the earliest stages of the pandemic but not at the later stages. Conclusion: With the imminent second wave of COVID-19, policy makers and health scholars may explore the efficacy of culture-specific policies, strategies, and social interventions in mobilizing social distancing measures.
Does Cultural Value Influence Consumers’ Attitudes toward Mall Events? A Study on Indian Mall Shoppers

Abstract The current study explores the influence of culture on consumers’ attitudes toward mall events and, consequently, its role in improving commitment toward malls. The study employed a mall-intercept technique for data collection across seven cities in India. Data were analyzed using structural equation modeling. The results indicated that cultural values predicted attitudes toward mall events. Mall events were categorized according to shopping motives typology and conceptualized as escape, exploration, social, epistemic, and flow. Among the four cultural values, power distance, collectivism, and masculinity were more effective in predicting consumers’ attitudes toward the various mall events dimensions. The research findings can help mall managers for planning events according to Indian consumers’ cultural beliefs.
Development of a nomogram to predict in-hospital mortality of sepsis-associated encephalopathy: a retrospective cohort study

Background Sepsis-associated encephalopathy (SAE) is related to an increased in-hospital mortality in patients with sepsis. We aim to establish a user-friendly nomogram for individual prediction of in-hospital death probability in patients with SAE. MethodsData were retrospectively retrieved from the Medical Information Mart for Intensive Care (MIMIC III) open source clinical database. SAE was defined by a Glasgow Coma Score (GCS) <15 at the presence of sepsis. Prediction model with a nomogram was constructed in the training set by Logistic regression analysis and then internally validated. A decision curve analysis (DCA) was performed to evaluate the net benefit of intervention with the nomogram. Results A total of 669 and 287 patients with SAE were randomly assigned to training set and internal validation set according to an allocation ratio of 7:3, respectively. Parameters eligible for the nomogram included age, Sequential Organ Failure Assessment (SOFA) score, red blood cell distribution width (RDW) and the mean values of heart rate, temperature and respiratory rate at first day of ICU admission. The nomogram exhibited good discrimination with an area under the receiver operating characteristic curve (AUROC) of 0.773 (95%CI: 0.729–0.818) in the training set and 0.741 (95%CI 0.673–0.809) in the validation set, respectively. Calibration of the derived model was also excellent, with Brier score of 0.136 (95%CI: 0.12­–0.153) and 0.168 (95%CI: 0.144–0.192) in both sets. The DCA of the nomogram indicated greater net benefit than SOFA. X-tile analysis showed that the nomogram can clearly stratify patients into three subgroups with different risks of in-hospital death. Conclusions The nomogram presents excellent performance in predicting in-hospital mortality of SAE patients, which can guide the prevention of SAE progression and may be more beneficial once specific treatments towards SAE are developed.
Study of the structure–bioactivity relationship of three new pyridine Schiff bases: synthesis, spectral characterization, DFT calculations and biological assays

Schiff bases exhibit a broad range of applications, including their use as catalysts, stabilizers, dyes, and intermediates in organic synthesis; and biological activities, such as antifungal properties. In this work, we synthesized and characterized three new pyridine Schiff bases L3 ((E)-2-{[(3-aminopyridin-4-yl)imino]-methyl}-4,6-di-chloro-phenol), L4 ((E)-2-{[(3-aminopyridin-4-yl)imino]-methyl}-6-chloro-phenol), and L5 ((E)-2-{[(3-aminopyridin-4-yl)imino]-methyl}-4-methyl-phenol) to explore their structure–bioactivity relationship as antifungal agents. We also synthesized and characterized a diamine-derived Schiff base (L6) that is similar to (E)-2-{[(3-aminopyridin-4-yl)imino]-methyl}-4,6-di-tert-butyl-phenol (L2, which previously demonstrated antifungal activity), but lacks the pyridine ring, to assess the impact of this structural modification on the biological properties. All the Schiff bases were characterized by FTIR, 1H and 13C NMR, DEPT, HHCOSY, TOCSY, UV-vis, MS, cyclic voltammetry, DFT calculations, and NBO to assess the stability of the intramolecular hydrogen bond (IHB). In addition, we determined the antimicrobial properties by obtaining the minimal inhibitory concentration (MIC) for Cryptococcus spp. (yeast) and Salmonella enterica (bacteria), and growth inhibition of Botrytis cinerea (mold). We found that the antifungal activity of these Schiff bases relied on the nitrogen atom in the pyridine ring, and the antifungal activity can be modulated by different substituents in the phenolic ring. In this work we provide data supporting a correlation between the structure and bioactivity in this kind of Schiff base. The understanding of the structural prerequisites for antimicrobial activity could contribute to designing new drugs.