Miracle-dz/UniFAR-FTUs huggingface dataset:
Analysis of Factors Affecting Individuals’ Online Consumer Credit Behavior: Evidence From China

In the past two decades, a growing number of Chinese young adults utilize online consumer credit to satisfy their increasing consumption demand. Although it is indeed boosting consumer markets, it has also caused many serious social problems. A number of previous studies discussed the authentication mechanism and legal supervision of online lending from a legal or economic perspective, and a small number of scholars explored factors affecting individuals’ online consumer credit from the perspective of behavioral psychology. Based on the Triandis model and existing studies on online lending, this paper constructs a theoretical model for the formation of individuals’ online consumer credit. It then adopts SmartPLS 3.00 to analyze the data set that involves 302 respondents in total. This research found that affect, facilitating conditions, perceived consequences and social factors have a significant impact on individuals’ online consumer credit. The findings of this study have political and practical implications. First, they can contribute to the rational consumption by China’s young generation and promote the sound development of online consumer credit. In the meantime, this study also helps online consumer credit platforms to provide better services and improve public relations.
Habitual Fish Oil Supplementation and Risk of Incident Inflammatory Bowel Diseases: A Prospective Population-Based Study

Background Inflammatory Bowel Diseases (IBDs) have been emerging in recent years with the advance of global industrialization and diet pattern transformation. Marine n-3 polyunsaturated fatty acids (n-3 PUFAs), enriched in fish oils, have well-known human health promotion. Evidence on the association of fish oil supplementation with the risk of developing IBDs was scarce. This study aimed to examine the association between the use of fish oil supplements and the risk of developing inflammatory bowel diseases (IBDs) among the general population. Methods We conducted a prospective cohort study of 447,890 participants aged 40–69 years from the UK Biobank. A touch screen questionnaire was used to get the data about fish oil intake at baseline. Incident diagnoses of IBDs were ascertained by the International Classification of Diseases (ICD-9 and ICD-10) or self-report. Cox proportional hazards model was applied to calculate hazard ratios (HRs) and 95% confidence intervals (CIs) of developing IBDs and their subtypes. Results We documented 1,646 incident cases of IBDs, including 533 incident cases of Crohn’s disease (CD) and 1,185 incident cases of ulcerative colitis (UC) during an average of 8 years of follow-up. After multivariate adjustment, the use of fish oil was associated with a 12% lower risk of IBDs (HR: 0.88, 95% CI: 0.78–0.99, p = 0.03) compared with non-consumers. For subtypes of IBDs, fish oil supplementation was inversely associated with a 15% lower risk of UC (HR: 0.85, 95% CI: 0.75–0.99, p = 0.02) but was not correlated with the risk of CD (p = 0.22). Besides, fish oil supplementation showed a significant inverse correlation with baseline CRP levels (β = –0.021, p < 0.001) and a positive association with baseline albumin levels (β = 0.135, p < 0.001) after adjustment for multiple variates. Conclusion Habitual intake of fish oil supplements was associated with a lower risk of IBDs and UC. Fish oil users tended to have lower baseline C-reactive protein levels and higher baseline albumin levels compared with non-users. It was concluded that fish oil supplement use may be recommended for the prevention and control of IBDs.
The Small Strain Stiffness Properties of Undisturbed Weathered Granite With Different Weathering Degrees

To evaluate the small strain stiffness properties of undisturbed weathered granite, the circular computer numerical control (CNC) abrasive wire sawing technology was applied to weathered granite sample processing and a series of resonance column tests were carried out to study the effects of weathering degree and effective consolidation pressure on dynamic shear modulus of undisturbed weathered granite. The results show that the degree of weathering and effective consolidation pressure have significant effects on the small strain stiffness properties of weathered granite. The samples with lower weathering degrees have higher dynamic shear modulus under the same effective consolidation pressure. The maximum dynamic shear modulus of samples with higher weathering degrees is more sensitive to effective consolidation pressure. Besides, a comparison between the experimental results with the previous results from other researchers indicates that the dynamic shear modulus ratio of weathered granite in the study area exceeds the parameter range obtained from others. According to the experimental results, a mathematical model of the relation between corrected standard penetration test (SPT) N ’ value and dynamic shear modulus was established, and besides, the variation range of dynamic shear modulus ratio of weathered granite in the study area was given, which may provide a reference for dynamic stability analysis of engineering in the study area.
Contribution of the Technical Efficiency of Public Health Programs to National Trends and Regional Disparities in Unintentional Childhood Injury in Japan

To achieve the Sustainable Development Goals, strengthening investments in health service inputs has been widely emphasized, but less attention has been paid to tackling variation in the technical efficiency of services. In this study, we estimated the technical efficiency of local public health programs for the prevention of unintentional childhood injury and explored its contribution to national trend changes and regional health disparities in Japan. Efficiency scores were estimated based on the Cobb–Douglas and translog production functions using a true fixed effects model in a stochastic frontier analysis to account for unobserved time-invariant heterogeneity across prefectures. Using public data sources, we compiled panel data from 2001 to 2017 for all 47 prefectures in Japan. We treated disability-adjusted life years (DALYs) as the output, coverage rates of public health programs as inputs, and caregivers' capacity and environmental factors as constraints. To investigate the contribution of efficiency to trend changes and disparities in output, we calculated the predicted DALYs with several measures of inefficiency scores (2001 average, yearly average, and prefecture-year-specific estimates). In the translog model, mean efficiency increased from 0.62 in 2001 to 0.85 in 2017. The efficiency gaps among prefectures narrowed until 2007 and then remained constant until 2017. Holding inefficiency score constant, inputs and constraints contributed to improvements in average DALYs and widened regional gaps. Improved efficiency over the years further contributed to improvements in average DALYs. Efficiency improvement in low-output regions and stagnated improvement in high-output regions offset the trend of widening regional health disparities. Similar results were obtained with the Cobb–Douglas model. Our results demonstrated that assessing the inputs, constraints, output, and technical efficiency of public health programs could provide policy leverage relevant to region-specific conditions and performance to achieve health promotion and equity.
Analysis of Multiple Health Risky Behaviours and Associated Disease Outcomes Using Scottish Linked Hospitalisation Data

Background Disease incidence and premature deaths tend to be influenced by multiple health risky behaviours, including smoking, excessive alcohol consumption and unhealthy diet. Risky behaviours tend not to be independent and may have a multiplicative effect on disease incidence and healthcare cost. Thus, understanding the interrelationship between health behaviours and their effect on health outcomes is crucial in designing behavioural intervention programmes. Objective To examine the interrelationship between health risky behaviours and associated disease outcomes amongst Scottish adults. Methods We use hospitalisation episode data from the Scottish Morbidity Records, (SMR), that have been administratively linked to Scottish Health Surveys (SHeS) respondents with target disease defined by relevant ICD9 and 10 codes. We apply a recursive multivariate probit model to jointly estimate the health risky behaviours and disease incidence to adequately control for unobserved heterogeneity. The model is estimated separately by gender. Results Modelling health risk behaviours and disease incidence equations independently rather than jointly may be misleading. We find a clear socioeconomic gradient predicting health risky behaviours and the results differ by gender. Specifically, smoking appears to be a key driver of other health risky behaviours. Current smokers are more likely to be drinking above the recommended limit, physically inactive, and eating inadequate diet. Conclusions Interventions targeting current smokers to quit could spillover to other behaviours by reducing excessive drinking, improve physical activity and adequate diet. Thus, improvements in one behaviour may increase the likelihood of adopting other healthier lifestyle behaviours.
Adipose-Derived Stem Cells for the Treatment of Diabetic Wound: From Basic Study to Clinical Application

Diabetic wounds significantly affect the life quality of patients and may cause amputation and mortality if poorly managed. Recently, a wide range of cell-based methods has emerged as novel therapeutic methods in treating diabetic wounds. Adipose-derived stem cells (ASCs) are considered to have the potential for widespread clinical application of diabetic wounds treatment in the future. This review summarized the mechanisms of ASCs to promote diabetic wound healing, including the promotion of immunomodulation, neovascularization, and fibro synthesis. We also review the current progress and limitations of clinical studies using ASCs to intervene in diabetic wound healing. New methods of ASC delivery have been raised in recent years to provide a standardized and convenient use of ASCs.
Attentional and Behavioral Disengagement as Coping Responses to Technostress and Financial Stress: An Experiment Based on Psychophysiological, Perceptual, and Behavioral Data

Discontinuance of information systems (IS) is a common phenomenon. It is thus critical to understand the decision process and psychophysiological mechanisms that underlie the intention and corresponding behaviors to discontinue IS use, particularly within the digital financial technology usage context, where continuance rates remain low despite increased adoption. Discontinuance has been identified as one coping behavior to avoid stressful situations. However, research has not yet explored this phenomenon toward digital financial technologies. This manuscript builds upon a pilot study that investigated the combined influence of technostress and financial stress on users’ responses toward digital financial decision-making tasks and aims to disentangle the specific impacts of unexpected technology behaviors and perceived financial loss on attentional and behavioral disengagement as coping responses, which may lead to discontinuance from digital financial technology usage. A two-factor within-subject design was developed, where perceived techno-unreliability as variable system response time delays under time pressure and perceived financial loss as negative financial outcomes were manipulated in a 3 × 2 design. Psychophysiological, perceptual, and behavioral data were collected from N = 15 participants while performing an adapted version of the Iowa Gambling Task. The results indicate that unexpected technology behaviors have a far greater impact than perceived financial loss on (1) physiological arousal and emotional valence, demonstrated by decreased skin conductance levels and curvilinear emotional valence responses, (2) feedback processing and decision-making, corroborated by curvilinear negative heart rate (BPM) and positive heart rate variability (HRV) responses, decreased skin conductance level (SCL), increased perceptions of system unresponsiveness and techno-unreliability, and mental workload, (3) attentional disengagement supported by curvilinear HRV and decreased SCL, and (4) behavioral disengagement as coping response, represented by curvilinear decision time and increasingly poor financial decision quality. Overall, these results suggest a feedforward and feedback loop of cognitive and affective mechanisms toward attentional and behavioral disengagement, which may lead to a decision of disengagement-discontinuance as a coping outcome in stressful human-computer interaction situations.
Relative Age Effect Among the Best Norwegian Track and Field Athletes of All Time: Comparisons of Explosive and Endurance Events

The purpose of this study was to investigate the degree of relative age effect (RAE) among the best Norwegian track and field athletes of all time, aged 13 years to senior, as well as to investigate the differences between athletes in events that impose different demands on their physical characteristics, categorised in endurance and explosiveness. The degree of RAE was investigated by examining the difference between the sample’s (N = 21,711) quarterly birth distribution and the quarterly distribution of birth of the Norwegian population as a whole from 1966 to 2019. To determine whether or not an RAE was present, chi-square tests (χ2) were conducted against an even distribution, with Cramer’s V (phi or ɸ) as a measure of effect size. The study’s results show a strong RAE in the two youngest age groups in both genders. RAE decreases with increasing age, but the effect is still present at the senior level in both men and women. Furthermore, the degree of RAE was strongest in explosive events in both boys (ɸ = 0.46) and girls (ɸ = 0.30), while in endurance events it was strong in boys (ɸ = 0.38) but not in girls (ɸ = 0.13). Prominent effect of RAE in the 13- and 14-year-old classes can be explained by the fact that in the youngest age groups impose the highest relative age difference. In addition, this is an age group where there are large differences in growth spurts, physical characteristics and training experience. Elimination of RAE with increasing age may be due to the fact that after puberty inherent physical advantages as a result of the month of birth are evened out. The prominent RAE in explosive events and in boys may be due to the fact that puberty and growth spurts make boys faster, stronger and larger, while puberty and growth spurts in girls are not always beneficial for girls in track and field events. The practical significance of the results relates to athletes developmental opportunities. Irrespective of whether young track and field athletes are relatively older or younger they should be met with patience and dedication from coaches. Superficial short-term categorization of young athletes potential do more harm than good.
Effects of Vaccination Against Influenza, Pertussis, and COVID-19 on Human Milk Antibodies: Current Evidence and Implications for Health Equity

Human milk contains three antibody classes that confer mucosal immunity to the breastfed infant: secretory IgA (SIgA), secretory IgM (SIgM), and IgG. Influenza and pertussis vaccines administered during pregnancy induce pathogen specific SIgA and IgG responses in human milk that have been shown to protect the breastfed infant from these respiratory illnesses. In addition, mRNA vaccines against the SARS-CoV-2 virus administered during pregnancy and lactation induce anti-SARS-CoV-2 IgG and IgA responses in human milk. This review summarizes the immunologic benefits of influenza, pertussis, and COVID-19 vaccines conferred by human milk. Additionally, future research direction in human milk immunity and public health needs to improve lactational support are discussed.
Alcohol Use Among Young Adults in Northern California During the COVID-19 Pandemic—An Electronic Health Records-Based Study

Background Individuals globally were affected by the COVID-19 pandemic in myriad of ways, including social isolation and economic hardship, resulting in negative impacts on mental health and substance use. Young adults have been subjected to extraordinary challenges such as job loss, virtual school, or childcare issues, but have received limited attention from research so far. Methods Using electronic health record data from a large integrated healthcare system in Northern California, this longitudinal observational study examined changes in the prevalence of unhealthy alcohol use (identified via systematic alcohol screening in adult primary care) from pre- (3/1/2019–12/31/2019) to post-COVID onset (3/1/2020–12/31/2020) among young adults (18–34 years). Among the 663,111 and 627,095 young adults who utilized primary care in the pre- and post-COVID onset periods, 342,889 (51.9%) and 186,711 (29.8%) received alcohol screening, respectively. We fit generalized estimating equation Poisson models to estimate the change in prevalence of unhealthy alcohol use from pre- to post-COVID onset among those who were screened, while using inverse probability weighting to account for potential selection bias of receiving alcohol screening. Heterogeneity in the change of prevalence by patient characteristics was also examined. Results Overall, the unadjusted prevalence of unhealthy alcohol use slightly decreased from 9.2% pre-COVID to 9.0% post-COVID onset. After adjusting for patient covariates, the prevalence of unhealthy alcohol use decreased by about 2% [adjusted prevalence ratio (aPR) = 0.98, 95% CI = 0.96, 1.00]. The prevalence of unhealthy alcohol use increased among women by 8% (aPR = 1.08, 95% CI = 1.06, 1.11), patients 18–20 years by 7% (aPR = 1.07, 95% CI = 1.00, 1.15), and Latino/Hispanic patients by 7% (aPR = 1.07, 95% CI = 1.03, 1.11). While the prevalence of unhealthy alcohol use decreased among men by 12% (aPR = 0.88, 95% CI = 0.86, 0.90), patients 21–34 years by 2% (aPR = 0.98, 95% CI = 0.96, 0.99), White patients by 3% (95% CI = 0.95, 1.00), and patients living in neighborhoods with the lowest deprivation indices by 9% (aPR = 0.91, 95% CI = 0.88, 0.94), their unadjusted prevalence remained higher than their counterparts post-COVID onset. There was no variation in the change of prevalence by comorbid mental health conditions or drug use disorders. Conclusions While changes in unhealthy alcohol use prevalence among young adults were small, findings raise concerns over increased drinking among women, those younger than the U.S. legal drinking age, and Latino/Hispanic patients.
Carcinogenicity of Poorly Soluble Low Toxicity Particles: Commentary on Epidemiology as a Risk Assessment “Reality Check”

Inhaled particles that are poorly soluble or insoluble and of low toxicity (“poorly soluble low toxicity” or “PSLT” particles), can accumulate in the lung and at lung overload levels induce lung cancers in rats. The question of whether PSLT particles increase lung cancer risk in humans is complicated by large differences between rats and humans and the relatively large particle doses administered in animal studies even when compared with heavy human occupational exposures. We review the findings of epidemiological studies on occupational exposure to each of three different PSLT particles (carbon black, talc and taconite). The epidemiological evidence indicates that at even very high occupational exposure levels at which non-malignant respiratory diseases including pneumoconiosis and even talcosis are observed, lung cancer risks appear not to be elevated. Although positive human cancer risks might be predicted based on extrapolation from overload doses in rats to relevant exposures in humans, the epidemiological “reality check” based on the three examples indicates that these PSLT particles are unlikely to increase lung cancer risk in humans even at high occupational levels of exposure. Therefore, we propose that careful evaluation of the epidemiological evidence can serve as a “reality check” for human risk assessment and help balance the risk evaluation process.
Immune Cells Profiles In The Peripheral Blood Of Patients With Moderate To Severe COVID-19 And Healthy Subjects With and Without Vaccination With The Pfizer-BioNTech mRNA Vaccine

Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), the causative agent of Coronavirus disease 2019 (COVID-19), has caused a global crisis. Patients with COVID-19 present with a range of clinical manifestations, from no symptoms to severe illness. However, little is known about the profiles of immune cells required to protect against SARS-CoV-2. This study was performed to determine the immune cells profiles in the peripheral blood of COVID-19 patients with moderate to severe disease (n=52), and compare the findings with those from healthy subjects vaccinated with Pfizer BioNTech mRNA vaccine (VS) (n=62), and non-vaccinated healthy subjects (HS) (n=30) from Kuwait. Absolute counts and percentages of total lymphocytes and lymphocyte subsets (CD3+ T cells, CD4+ T cells, CD8+ T cells, CD19+ B cells, and CD16+CD56+ NK cells) in the peripheral blood of the three groups were analyzed using flow cytometry. The results showed that the absolute counts of total lymphocytes, CD3+, CD4+, and CD8+ T cells, CD19+ B cells, and CD56+ NK cells, were significantly lower in COVID-19 patients than normal healthy controls and vaccinated subjects. The percentages of CD3+ and CD4+ T lymphocytes were also significantly lower in the COVID-19 patients. However, the percentage of CD16+CD56+ NK cells was significantly higher in the peripheral blood of COVID-19 patients, compared to the HS and VS groups with no detectable differences in the percentages of CD8+ T cells and CD19+ B cells between the three groups. Analysis of the monocyte subsets has showed a significantly higher percentage of CD14+HLA-DR+ monocytes in COVID-19 patients compared to HS whereas the inflammatory CD14+CD16+ HLA-DR+ monocytes, and the non-classical CD16+HLA-DR+ monocytes showed significantly lower frequency in the blood of the patients than that of HS. These findings demonstrate perturbations of both innate and adaptive immune cell subsets that reflect dysregulated host responses in COVID-19 patients with moderate to severe disease.