Miracle-dz/UniFAR-FTUs huggingface dataset:
Determination of Cefepime Residues in Different Rabbit Tissues using High Performance Liquid Chromatography

| Drug Residues in meat have serious effects on human health (e.g., increase antimicrobial resistance, carcinogenicity, mutagenicity, and hypersensitivity) which urge the control of veterinary drug residues to ensure consumers’ health. Thus, this work was designed to determine cefepime residues quantitatively in different tissues of the rabbits (liver, kidneys and muscles) and to determine the withdrawal time of cefepime following intra-muscular (I/M) dosing of the drug using high performance liquid chromatography (HPLC). Twenty four healthy male rabbit (growing white New Zealand) were used and randomly allocated into two equal groups, 12 rabbits/each; group 1 (negative control) was I/M injected with sterile normal saline and group 2 was I/M injected with cefepime hydrochloride (75 mg/kg BW) once daily for 5 successive days. Rabbits were sacrificed on 1st, 3rd, 7th and 14th day post antibiotic injection and liver, kidney and breast muscles samples were collected for detection of residue by HPLC. Results showed that days of experiment and tissue type has an effect on cefepime residual level as there is highly significant interaction (p =0.0001). The highest cefepime residual level was detected in kidney followed by liver while the lowest level was recorded in muscle samples. Cefepime remained within the detectable limit in the breast muscle (on the 3rd day) and in the kidney and liver tissues (on the 7th day) following the last I/M injection of the drug. While on the 14th day after last dose, the cefepime residues were disappear in all tested tissues. Cefepime administration caused non-marked changes of tested biochemical indices (liver, and kidney function tests) of rabbit then reached to safe levels during the withdrawal period at other time points. Therefore, it is recommended to pay attention to the proper withdrawal time (14 day) before slaughtering of cefepime-treated rabbits to make sure that rabbits tissues are free from cefepime residues and become safe for consumers.
Effect of foliar application of potash and micronutrients on growth and yield attributes of groundnut

A field experiment was conducted during summer season of 2012 on medium black soil to study the effect of foliar application of potash and micronutrients on growth and yield attributes of groundnut. The experiment consisted of six treatments (control, K @ 0.5%, Fe @ 0.5%, Zn @ 0.5%, B @ 0.2% and K @ 0.5% + Fe @ 0.5% + Zn @ 0.5% + B @ 0.2% at 40 DAS as foliar spray) thereby making six treatments tested in randomized block design with four replications. Results indicated that the application K @ 0.5% + Fe @ 0.5% + Zn @ 0.5% + B @ 0.2% foliar spray at 40 DAS results is significantly higher the plant height, number of branches per plant, dry matter at 45 and 75 DAS, number of nodules per plant, pod weight, 100 kernel weight, shelling per cent, pod and haulm yield. However, day to 50% flowering, CGR, RGR and test weight did not significantly influenced by various foliar applications.
Development of shelf stable tomato rasam paste using hurdle technology.

The objectives of this work were to develop ready-to-use tomato rasam paste using hurdle technology involving water activity (a w ), temperature, pH and preservative as hurdles and evaluation of shelf stability of the developed product. Physico-chemical characteristics such as pH, titratable acidity (TA), colour changes, and microbiological profiles were evaluated during storage of 4 months at ambient temperature (AT, 28 ± 4oC) and 37oC. Hunter color analysis showed significant (P<0.05) decrease in the lightness (L * ) and redness (a * ) while yellowness (b * ) of paste increased during storage at both the storage temperatures. The L * value decreased from 27.23 to 20.78 and 18.23 in samples stored at AT and 37oC, respectively while a * values decreased from 34.29 to 30.02 and 31.21 in samples stored at AT and 37oC, respectively. The paste was found to be acceptable on sensory scale after 4 months of storage at ambient temperature. The quality of paste in terms of sensory colour attribute was found to be deteriorated in sample stored at higher (37oC) temperature.
PENGARUH ETOS KERJA, MOTIVASI, DAN IKLIM ORGANISASI TERHADAP KINERJA DEPARTEMEN ASSET & OFFICE MANAGEMENT PT SEMEN BATURAJA (PERSERO) TBK

This research aims to know the analysis result on Work Ethics, Motivation and Organization Climate on The Performance of Asset & Office Management Department at PT Semen Baturaja (Persero) Tbk, both partially and simultaneously. This research is a quantitative research using associative, survey and descriptive method. In analyzing data, doubled linear analysis is used. The population is all 31 personnils of Asset & Office Management Department. The test value of work ethics, motivation and organization climate do not impact on the performance, with thitung -0.053 F tabel(2, n-2) 2,93. Correlation Coefficient (R) 0,730 shows strong positive relation and determination coefficient (R2) 0,532 shows 53,2% from performance variable of Asset & Office Department can be described by work ethics, motivation and organization climate and 46,8% is impacted by other variables. Thus, if work ethics, motivation and organization climate increased partially, would not increase the performance of Asset & Office Management Department, but, if it is increased simultaneously, the performance of Asset & Office Management Department would increase.
Common beans variability on physical, canning quality, nutritional, mineral, and phytate contents

Abstract Common beans are nutrient-rich crops, an important source of protein, micro minerals (Fe and Zn), and vitamins. Varieties of beans have been releasing by the Ethiopian Institute of Agricultural Research, but for some varieties, a comprehensive nutritional content was not studied. Therefore, the study aims to identify varieties having a better nutritional quality and canning quality, besides research has to be done for profiling. Results of the present finding revealed that significant differences were observed at P ≤ 0.05 for all analyzed parameters. The seed weight/100 seed, cooking time, and percent of non-soakers were varied respectively from 17.18–53.17 g/100 seed, 30.0–51.33 min, and 0.0–4.00%, meanwhile percentage washed drained weight and hydration coefficient value was found to be 60.06–64.47%, and 1.25–1.68. Visual appearance quality parameters; starchiness, clumping, and splitting degree were also enclosed and significant differences were observed. Proximate compositions such as fiber, ash, and protein contents were covered from 4.07–7.33, 3.62–4.60 and 17.96–25.73%, respectively. Iron and Zinc values also found in the array of 0.02−36.6 and 0.49−5.45 as measured by mg/100 g, and phytate value was found to be 8.1–23. 59 mg/g. According to this research finding PAN-182, G-4445, and Roba bean varieties were found best for canning purpose and nutritional quality. Therefore, selected bean varieties should be considered for developing bean-based protein and micronutrient-rich food, canning industry, and bean breeders.
Acceptability and Feasibility of the CHARISMA Counseling Intervention to Support Women’s Use of Pre-Exposure Prophylaxis

Background: Women may need or seek male partner approval to {Malow, 2000 #18}{Malow, 2000 #18}{Malow, 2000 #18}{Malow, 2000 #18}safely and consistently use oral antiretroviral pre-exposure prophylaxis (PrEP) or vaginal microbicides. We developed CHARISMA, a counseling intervention to support women’s relationships and their ability to consistently use HIV prevention products.Methods: In a pilot study with 95 female participants in Johannesburg, South Africa, lay counselors assessed participants’ relationship(s) with their male partner(s) and barriers or facilitators to HIV prevention method use, and then provided tailored, interactive counseling. We conducted study participant surveys and clinic staff interviews to evaluate CHARISMA’s feasibility and acceptability.Results: The CHARISMA pilot study indicates that a two-session relationship counseling intervention with 6-month follow-up to support women’s ability to safely and effectively use vaginal microbicides was generally acceptable and feasible. Most participants thought CHARISMA was relevant, helpful, and about the right length, and that it had a positive impact on their relationships with their partners and their product use. Staff stated that it was generally feasible to implement. Based on these promising preliminary findings, the project team is currently conducting a randomized controlled trial in which participants are receive either the standard of care for IPV screening and referral (control arm) or the CHARISMA intervention.Conclusions: Clinic staff felt strongly that the length and intensity of CHARISMA were necessary for participants to begin to trust the counselors enough to be open and honest about problems in their relationships, and to begin to overcome the normalization of intimate partner violence. The length and intensity of CHARISMA may not be feasible in some settings, but a shorter version of the intervention may not offer as much support as women and staff need. One possible approach to reduce the burden on clinic staff would be to self-administer the intervention through a computer rather than requiring a counselor. Lessons learned from the pilot study may be relevant to others developing interventions supporting women’s use of oral PrEP or vaginal microbicides.
Risk factors of placenta previa with maternal and neonatal outcome at Dongola/Sudan

Background: Placenta previa is a major cause of hemorrhage affecting 0.4–0.5% of all pregnancy's early detection of cases and senior input will significantly reduce maternal and fetal morbidity and mortality. Objectives: The aim of the study is to determine risk factors, fetal and maternal outcome in pregnancy complicated by placenta previa. Method: This is descriptive cross-sectional study in women diagnosed with placenta previa at Dongola maternity hospital, Sudan from December 2018 to June 2019. Results: There were 3,674 deliveries and 52 cases of placenta previa during the study period with prevalence of 1.4%. The average age of the patients was 34.8 years and most of them were above 35 years (53.8%), and (63.5%) were para 3 and more. Other identified risk factors included previous cesarean section (69.1%), previous uterine evacuation (13.5%), and assisted reproductive technique (5.8%). Maternal complications were hemorrhage needing blood transfusion (40.4%), cesarean hysterectomy (21.2%), and bladder injury (3.8%), but (34.6%) were with good outcome and no maternal death. NICU admission with RDS (25%), prematurity (25%), and death (5.8%) were the fetal complications, while in (44.2%) fetal outcome was good. Conclusion: The most identifiable risk factors for placenta previa were previous uterine scars, advanced maternal age, and multiparity. And it is associated with adverse maternal and fetal outcomes.
Bone scan index on bone scintigraphy and radiation therapy for bone metastases from cancers other than prostate and breast cancers: A retrospective observational study

Objective: In this study, we aimed to use new automatic analysis software (VSBONE bone scan index (BSI); Nihon Medi-Physics, Tokyo, Japan) to investigate whether the pre-radiation therapy (RT) BSI, derived from bone scintigraphy (BS) images, is a prognostic indicator in patients undergoing RT for bone metastases from cancers other than breast or prostate cancer. Materials and Methods: In this retrospective single-institution study, we analyzed data of 51 patients who had undergone whole-body scintigraphy before receiving RT for bone metastases from cancers other than breast and prostate cancer between 2013 and 2019. Their bone metastases preradiation BSI were automatically calculated using newly developed software (VSBONE BSI; Nihon Medi-Physics, Tokyo, Japan). Univariate and multivariate analyses were performed to identify associations between selected clinical variables and overall survival (OS). Results: We did not find a significant association between BSI and OS. However, we did find that younger patients had significantly better OS than older patients (P = 0.016 and P = 0.036, respectively). In addition, BSI were significantly lower in patient with solitary or osteolytic bone metastases than in those with osteoblastic or mixed bone metastases (P = 0.035 and P ≤ 0.001, respectively), and significantly higher in those with lung cancer than in those with other types of cancer (mean BSI 3.26% vs. 1.97%; P = 0.009). Conclusion: The only significant association with survival identified in this study was for age at the time of BS and at time of diagnosis of bone metastases.
Influence of suture diameter on microsurgical ureterorrhaphy in rabbits: an experimental study

Background Ureteral obstruction is a common indication for surgical intervention, due to the small size of the ureter, specialized instrumentation is required such as operating microscope for intraoperative magnification and microsutures. The aim of this study is to evaluate and compare 3 sizes of nylon 6 − 0,8 − 0,10 − 0 for ureterorrhaphy in the ureter of rabbits, using microsurgical technique. Results A total of fifteen male, adults, New Zealand rabbits were divided in three groups: all groups were submitted ureterotomy. A 2 mm longitudinal incision was made in the medial portion of the right ureter, followed by a partial perforating simple interrupted 6 − 0, 8 − 0 and 10 − 0 sutures in each group. During the experiment ultrasound evaluations were performed to assess the kidney length and width, the presence of ureteral calculi, the renal pelvic dilation, the ureter diameter and the presence of free liquid in the abdominal cavity. At the end of the experiment all kidneys and ureters were submitted to macroscopic and histopathological evaluations. In the first ultrasound assessment, all groups had an acute increase in renal length (p < 0.048). The group with 8 − 0 suture showed a difference in ureteral diameter on the 5th day (p < 0.01) and all groups showed a reduction in diameter on the 30th day. The group with 6 − 0 suture showed a high mortality rate during the experimental period and the histopathological evaluation exhibited areas of necrosis. According to the ultrasound evaluation caliber 10 − 0 achieved better results in, macroscopic and microscopic evaluations. The finer suture diameters had better outcomes according to the ureteral inflammation scores. Conclusions The use of 10 − 0 suture resulted in lower rates of ureteral inflammation, renal changes and postoperative complications when compared to two other sizes of the same material.
Linking insecticide-treated mosquito nets to malaria: The roles of malaria Knowledge and household-income

Background: Drawing on the theory of the health belief model, this study examined the interplay between insecticide-treated mosquito nets, malaria-knowledge, household income, and malaria. The study was premised on the notion that insecticide-treated mosquito nets are positively related to malaria prevalence; and that knowledge mediates the relationship between insecticide-treated mosquito nets and malaria. Furthermore, household-income was hypothesised to have a moderating effect on the direct and indirect relationships (through malaria knowledge) between insecticide-treated mosquito nets and the prevalence of malaria. Methods: The hypothesised relationships were examined using panel data collected from ten regions of Ethiopia during 2011 – 2015. Structural equation modelling and the random effect model were used to test the hypotheses. Statistical analyses were performed using Stata version 13.0. Results: The results were consistent with our proposed hypotheses, showing a significant relationship between the research variables. Accordingly, our findings suggest that malaria knowledge contributes to improving the relationship between insecticide-treated mosquito nets and malaria prevalence. The results revealed a positively significant indirect effect (β = 0.47, p = 0.003) as well as a positively significant direct effect (β = 0.28, p = 0.001). Further, the study showed a positive impact of household-income in strengthening the relationship between insecticide-treated mosquito nets and malaria through knowledge, with a considerable value (β = 0.13, p = 0.000). Conclusion: The findings are potentially useful for the health sector to ensure success in infectious disease prevention and control, particularly malaria, and to explain how various factors contribute to the relationship.
Mechanistic Study on Water Gas Shift Reaction on the Fe3O4 (111) Reconstructed Surface

We present a first-principles study using periodic density functional theory on a water gas shift reaction on a Feoct2-tet1-terminated Fe3O4 (111) surface. We show that water can easily undergo dissociative adsorption to form OH and H adatom species on the surface. Three possible reaction mechanisms (i.e., redox mechanism, associative mechanism, and coupling mechanism) were systematically explored based on minimum energy path calculations. It was identified that the redox mechanism is the energetically most favorable pathway for the water gas shift reaction on the Feoct2-tet1-terminated Fe3O4 (111) surface. The COO* desorption was found to be the rate-limiting step with a barrier of 1.04 eV, and the OH dissociation has the second-highest activation barrier (0.81 eV). Our results are consistent with results of kinetic and isotope exchange experiments. Our studies suggest that it is necessary to develop a promoter to reduce the activation barriers of the COO* desorption and OH dissociation steps in order to.
Learning Dynamic User Interest Sequence in Knowledge Graphs for Click-Through Rate Prediction

Despite that path-based and embedding-based models with knowledge graphs (KGs) achieve better recommendation performance compared with other deep learning based methods, such improvement is limited due to a lack of modeling user’s dynamic interest. To address this issue, we explore a principled model to provide semantic understanding of each item in user’s historical interest sequence in KGs. Specifically, we propose a multi-granularity dynamic interest sequence learning method, which is based on knowledge-enhanced path mining and interest fluctuation signal discovery, to obtain semantic-enhanced paths. Furthermore, the paths are embedded by the SEP2Vec, and merged through the proposed entropy-aware pooling layer to obtain the user preference representation, which is then used to learn dynamic user interest sequence. Experimental results on two public datasets of movie and music recommendation, and two industrial datasets of personalized local service recommendation in Alipay App have illustrated that the proposed model can achieve significantly better prediction performance compared with other known baselines.
The Fable of Regional Tourists’ Loyalty to Bhutan

Tourism is one sector that has reached the zenith of maturity with visitors possessing vast travel experiences compelling them to behave in a selective manner thereby making the destinations fiercely competitive (Moreno-Gil & Coca-Stefaniak, 2020). Paulauskaite, Powell, Coca-Stefaniak, and Morrison (2017) in their study revealed that tourists search for convenient and more authentic experiences fueled by a wide range of disposable incomes leading to drastic change of tourism ecosystem as well as tourism destinations at all levels. Bhutan has embarked upon a tourism business only from 1974 and the industry emerged as second highest revenue generator next to hydropower. The study conducted by Khan, Bibi, Lorenzo, Lyu, and Babar (2020) revealed tourism industry as a competent driver of development in emerging economies. They further found significant and positive relationship between increase in tourism receipts and gross domestic product (GDP), increase in foreign direct investment (FDI), and reduction of poverty in the long run. Bhutan Tourism Monitor (BTM) Report 2019 has revealed the total annual arrivals as 315,599 that proportionate about 42.9 percent of Bhutan‘s total population. Out of this total arrivals, 243,400 (77.1%) are regional arrivals, which is an increase of 20.3 percent from the previous year. The growth in inbound tourists has been skyrocketing with an annual average growth rate of 17.1 percent for the straight seven years (2013-2019). Tourism sector in Bhutan has been contributing towards the country‘s socio-economic development and revenue generation ever since its inception. The year 2019 saw total gross foreign exchange receipts of US$345.88 million that accounted for a growth of 3.8 percent from the previous year. To this effect, a complete comprehension of the regional tourists‘ perception of Bhutan as a travel destination of their choice and the associated factors responsible for their loyalty is of paramount importance to the Tourism Council of Bhutan (TCB) and all those involved in tourism industry for sound formulation of marketing policies and product diversification. The TCB has defined regional arrivals as those inbound tourists from India, Bangladesh and Myanmar and the rest of the world falls under the category of ̳international arrivals. ‘ Regional arrivals that comprised over three-quarters of the total visitors to Bhutan is of a great concern to the tourism marketers and the TCB for the tourism governance to sustain the inflow of the same, which in turn to sustain tourist receipts, foreign exchange revenue to government, and employment generation (Dorji, 2001).
Evaluation of postharvest properties in different passion fruit species during ripening

During ripening, many transformations occur in passion fruits. The ripening stage affects fruit quality and post-harvest properties. Fruits with 65% yellow epidermis present chemical characteristics that meet industrial standards, facilitating harvest estimations and loss avoidance. Thus, this study aimed to evaluate the post-harvest properties of passion fruit species (genotypes of the yellow passion fruit and sweet passion fruit, and yellow passion fruit cultivar FB 200) during ripening. The fruits were evaluated by the color of the epidermis and the chemical characteristics of the pulp (titratable acidity, vitamin C, carotenoids, soluble solids content, and ratio). This experiment was conducted with a completely randomized design and a split-plot arrangement, where the plots were the species and the subplots were the evaluation periods (50, 58, 66, 74 and 82 days after anthesis), with four replications and 10 fruits per plot. The yellow passion fruit genotype and cultivar, harvested at 82 days after anthesis, presented desirable characteristics for the juice industry and for fresh consumption. The sweet passion fruit had a higher soluble solids content and titratable acidity ratio because of its high content of soluble solids and low acidity, which translate to a better fruit flavor.
Calixarene-based amphiphiles : synthesis, self-assembly and interaction with DNA

The present doctoral thesis focused on the synthesis of amphiphilic calix[4]arenes, the study of their self-assembly properties at the air-water interface as Langmuir monolayers or in solution as nanoparticles and on the DNA-binding properties of the resulting self-assembled structures. The objective is to improve the understanding of the interaction of amphiphilic calixarene-based nanoparticles with DNA molecules, and to improve the comprehension of the effect of the calixarene structure: on the self-assembly of the amphiphilic calixarene as nanoparticles and on the interaction of the calixarene-based nanoparticles with DNA. The results reported in my PhD dissertation highlight the influence of the calixarene structure, on their self-assembly as Langmuir monolayer at the air-water interface and as nanoparticles in water. Moreover the binding mechanism between the DNA phospho-diester backbone and the self-assembled calix[4]arene is dependent of the number of recognition moieties but is also governed by a sequence dependent interaction mechanism.