Miracle-dz/UniFAR-FTUs huggingface dataset:
Cognitive Assessment Strategy Using Cmaptools Application with Rasch Modeling

This study aims to find a fit model instrument consisting of the validity and reliability of cognitive assessment using the campstool and the distribution of student achievement in making concept maps as a cognitive assessment strategy. As we know, the assessment of cognitive aspects is one way to assess student learning outcomes. Cognitive abilitiy is the basis of the development of students' thinking skill. One application that can be used to assess students' cognitive abilities is the CMAPTOOL concept map application developed by the Institute of Human and Machine Cognition (IHMC). The research method category is quantitative research. Students' cognitive abilities through the use of the CMAPTOOL application were then assessed using the concept map assessment indicators. The indicator assessment consist of 5 aspects including concept formation, principle formation, understanding concept linkage, problem solving and composing section. The type of concept map assessment used is a fill-in map scheme. The values obtained from the assessment of the concept map were analyzed through Rasch modelling. The results showed that the assessment tools with validity 0.69 and reliability of model 0.59. The results of the mastery of students' cognitive abilities are categorized in mastery levels 1 to 4. Cognitive assessment using CMAPTOOL can be used as strategy to assess student achievement .
Physiologically Based Pharmacokinetic (PBPK) Model of Gold Nanoparticle-Based Drug Delivery System for Stavudine Biodistribution

Computational modelling has gained attention for evaluating nanoparticle-based drug delivery systems. Physiologically based pharmacokinetic (PBPK) modelling provides a mechanistic approach for evaluating drug biodistribution. The aim of this work is to develop a specific PBPK model to simulate stavudine biodistribution after the administration of a 40 nm gold nanoparticle-based drug delivery system in rats. The model parameters used have been obtained from literature, in vitro and in vivo studies, and computer optimization. Based on these, the PBPK model was built, and the compartments included were considered as permeability rate-limited tissues. In comparison with stavudine solution, a higher biodistribution of stavudine into HIV reservoirs and the modification of pharmacokinetic parameters such as the mean residence time (MRT) have been observed. These changes are particularly noteworthy in the liver, which presents a higher partition coefficient (from 0.27 to 0.55) and higher MRT (from 1.28 to 5.67 h). Simulated stavudine concentrations successfully describe these changes in the in vivo study results. The average fold error of predicted concentrations after the administration of stavudine-gold nanoparticles was within the 0.5–2-fold error in all of the tissues. Thus, this PBPK model approach may help with the pre-clinical extrapolation to other administration routes or the species of stavudine gold nanoparticles.
The Arctification of northern tourism: a longitudinal geographical analysis of firm names in Sweden

ABSTRACT The European North has long attracted travelers, the selling point often being the availability of nature and wilderness. Recent developments, however, suggest a greater variety of tourism motivations, including new products such as dogsled tours, aurora borealis watching, snowmobiling, and stays at ice hotels. Many of these firms use names containing the term ‘Arctic' or similar terminology related to imaginations of the Far North. The chosen terminology is considered one example of the process of ‘Arctification'. However, there is a limitation in descriptive knowledge about the overall Arctification of the region’s tourism industry. Hence, this article aims to illustrate the Arctification of the tourism industry by mapping the changing geographies of firm names. Through its results, the study aims to contribute an understanding of how firm naming is part of the tourism production, and how this influences the reimaging and delineation of regions. The study uses a descriptive quantitative approach, extracting data from the Retriever Business database. The results show a clear development of tourism firms increasingly using Arctic terminology in their firm names. Also, the tourism firms’ locations show patterns of spatial differences related to the region’s natural environment, population density, infrastructure, and the firms’ age.
Severity of adverse reactions is associated with T-cell response in mRNA-1273 vaccinated health care workers

Knowledge about mRNA-1273 elicited T-cell response is limited. We investigated adverse reactions and interferon gamma release by specific T-cells among mRNA-1273 vaccinated health care workers. Seven to 13 weeks after complete vaccination low levels of specific T-cells were detected not correlating with antibody response. Severity of symptoms after first and number of symptoms after second immunization were associated with T-cell response. Assessment of T-cell response in addition to antibody response is crucial because even few specific T-cells could add to protection against infection. Investigation of mRNA-1273 induced inflammatory processes might help improve reactogenicity and immunogenicity.
Mechanics of the turbulent/non-turbulent interface of a jet

We report the results of an experimental investigation of the mechanics and transport processes at the bounding interface between the turbulent and nonturbulent regions of flow in a turbulent jet, which shows the existence of a finite jump in the tangential velocity at the interface. This is associated with small-scale eddying motion at the outward propagating interface (nibbling) by which irrotational fluid becomes turbulent, and this implies that large-scale engulfment is not the dominant entrainment process. Interpretation of the jump as a singular structure yields an essential and significant contribution to the mean shear in the jet mixing region. Finally, our observations provide a justification for Prandtl’s original hypothesis of a constant eddy viscosity in the nonturbulent outer jet region.
A Statistical Analysis of the Effectiveness of Selected Methods in the Teaching of Mathematics

(how perceived by students: appropriate – impropriate) . Character B denotes students’ level of understanding mathematics. Character A takes the categories A 1 (cid:3) excellent, A 2 (cid:3) very good, A 3 (cid:3) sometimes convenient, sometimes inconvenient, A 4 (cid:3) mostly inconvenient, A 5 (cid:3) absolutely inconvenient. Character B takes the categories B 1 (cid:3) subject matter always understood, B 2 (cid:3) subject matter understood most of the time, B 3 (cid:3) subject matter understood on 50% of lessons, B 4 (cid:3) subject matter rarely understood, B 5 (cid:3) subject matter never understood. We present the results of pedagogical experiment, which has verified the effectiveness of three teaching procedures used to teach selected units of secondary school mathematics. The primary experiment was preceded by a pilot survey realized among 200 first-grade students of the University in Zilina. The aim of the survey was a determination of the degree of contingency between two qualitative signs: the level of understanding mathematics and the teaching style in the teaching of mathematics. Regarding the obtained results the statistical methods of the single-factor analysis of variance for balanced model and Duncan’s multiple range test were used to specify the most effective teaching method. The results of the experiment unambiguously confirm the teaching supported by the use of information technologies as the most effective method in the teaching of mathematics.
The Impaction of Laparoscopic versus Laparotomy for Lymphovascular Space Invasion of Early Cervical Cancer: A Multicenter Retrospective Study

Objectives: The aim of this study was to compare the lymphovascular space invasion between laparoscopic radical hysterectomy (LRH) and abdominal radical hysterectomy (ARH). Materials and Methods: One retrospective study was conducted with 391 patients treated with 242 patients underwent ARH and 149 patients underwent LRH between May 2010 and August 2019. We collected clinicopathological and perioperative outcome from medical records. We adopt Student's t-test and Chi-square test was used to compare continuous and categorical variables between LRH and ARH. Results: Our research found that there was no difference in tumor size, histology, pathology grades, positive lymph nodes, and postoperative complications between LRH and ARH (P > 0.05). The estimated blooding loss (EBL) and length of postoperative hospital stay were less for LRH than ARH (248.12 ml vs. 412.56 ml, P < 0.05, and 10.48 days vs. 15.16 days, P < 0.05). The mean operative time was longer for LRH than ARH (227.51 min vs. 215.62 min, P < 0.05). Significant difference was found in intraoperative complications (P < 0.05). However, LVSI was higher for LRH than ARH (36.8% vs. 19.8%, P < 0.05). We discovered that the LVSI was related with International Federation of Obstetrics and Gynecology stage and tumor size. Conclusion: Compared to ARH, the LRH would be advantageous for early cervical cancer in terms of EBL, length of postoperative hospital stay, and intraoperative complications. The ARH was superior to LRH in operative time. In addition to, LRH was more likely to lead to LVSI. Furthermore, when tumor size or stage was increasing, LRH was easily to generate LVSI. But, we cannot confirm recurrence rate is related to LVSI.
Antimicrobial and Antibiofilm Coating of Dental Implants—Past and New Perspectives

Regarded as one of the best solutions to replace missing teeth in the oral cavity, dental implants have been the focus of plenty of studies and research in the past few years. Antimicrobial coatings are a promising solution to control and prevent bacterial infections that compromise the success of dental implants. In the last few years, new materials that prevent biofilm adhesion to the surface of titanium implants have been reported, ranging from improved methods to already established coating surfaces. The purpose of this review is to present the developed antimicrobial and antibiofilm coatings that may have the potential to reduce bacterial infections and improve the success rate of titanium dental implants. All referred coating surfaces showed high antimicrobial properties with effectiveness in biofilm control, while maintaining implant biocompatibility. We expect that by combining the use of oligonucleotide probes as a covering material with novel peri-implant adjuvant therapies, we will be able to avoid the downsides of other covering materials (such as antibiotic resistance), prevent bacterial infections, and raise the success rate of dental implants. The existing knowledge on the optimal coating material for dental implants is limited, and further research is needed before more definitive conclusions can be drawn.
Evaluate the Importance of Translanguaging in Language Learning Classes

With the increasing development of international communication, most people regard foreign language learning as a top priority and make it a part of their daily life. More and more attention is being paid to the study and application of foreign languages, which highlights the significance of choosing a proper teaching method in language learning. This essay illustrates different means of teaching in language education classrooms and makes a comparison between these different types of teaching methods. In this connection, the paper takes the approach of doing a literature review about language learning classrooms. In previous papers, various teaching patterns were examined, and in this essay, different approaches to foreign language education will be evaluated and compared. There are advantages and disadvantages of multilingual education, this essay will evaluate monolingual education and argue that it causes more negative impacts than positive impacts, and it needs more improvements. This essay will first examine the arguments in favor of monolingualism from the perspectives of both educators and students, as well as provide an introduction and evaluation of bilingual classrooms, before arguing that translanguaging can provide more benefits in language learning and highlighting its importance in bilingual education.
Biogenic Synthesis of AgNPs Using Aqueous Bark Extract of Aesculus indica for Antioxidant and Antimicrobial Applications

Nanotechnology has received a lot of attention from the scientific community because of the greater surface-to-volume ratio of nanomaterials, which phenomenally increases their efficacy in practical applications. Among the various synthesis techniques, the biogenic or green synthesis of nanomaterials shows advantages over other techniques such as physical, chemical, etc. This study reports the biogenic synthesis of silver nanoparticles (AgNPs) using aqueous bark extract of Aesculus indica. The as-synthesized NPs were characterized by UV–visible, FT-IR, XRD, and SEM, and then tested for their antioxidant and antimicrobial potency. We have identified phenols, flavonoids, tannins, saponins, and carbohydrates in the bark extract of A. indica. The extract-loaded-AgNPs showed the highest inhibition for Staphylococcus aureus (28.0 mm), Pseudomonas aeruginosa (17.66 mm), Escherichia coli (14.33 mm), Acetobacter serratia (14.00 mm), and Klebsiella pneumoniae (12.33 mm). The methanolic bark extract inhibited S. aureus (24.33 mm), P. aeruginosa (10.66 mm), E. coli (11.33 mm), A. serratia (9.66 mm), and K. pneumoniae (11.66 mm). Aqueous bark extract inhibited S. aureus (22.33 mm), P. aeruginosa (8.33 mm), E. coli (9.33 mm), A. serratiaa (8.33 mm), and K. pneumoniae (9.66 mm). Its aqueous extract showed the highest antioxidant potency; IC50 (0.175 µg/mL) followed by the methanolic extract; IC50 (0.210 µg/mL) and extract-loaded nanoparticles; IC50 (0.901 µg/mL). Our findings provide meaningful interest for antioxidant, anti-microbial applications of, and AgNPs synthesis by, aqueous bark extract of A. indica.
High-Moment FeCo Magnetic Nanoparticles Obtained by Topochemical H2 Reduction of Co-Ferrites

Cobalt ferrite nanoparticles of different stoichiometries synthesized by a sol–gel autocombustion method were used as a starting material to obtain high-moment Fe50Co50 and Fe66Co34 metal nanoparticles by topochemical hydrogen reduction. Structural and magnetic investigations confirmed the formation of FeCo nanoparticles with crystallite sizes of about 30 nm and magnetization at 0.5 T of ~265 Am2/kg (0 K), which was larger than the expected bulk value, likely because of the incorporation in the body-centered cubic (bcc) FeCo structure of the residual C atoms present on the surface of the oxide particles. Temperature-dependent magnetization measurements in the H2 atmosphere were also performed to investigate in detail the reduction mechanism and the effect of an external magnetic field on the process efficiency.
Kinetics of Chromium Reduction Associated with Varying Characteristics of Agricultural Soils

Chromium (Cr)(VI) is carcinogenic; thus, the excessive presence of Cr(VI) in soils can pose potential risks to water quality, food safety, and human health. The kinetics of Cr(VI) reduction in soils are important for assessing the fate of Cr in the environment. The present study tested physio-chemical and microbial properties in twenty-eight agricultural soils collected in Taiwan to evaluate the relationship between the reduction rate of Cr(VI) and soil properties, using 49-day incubation at 25 °C. At the beginning of incubation, 100 mg Cr(VI) kg−1 was spiked into the soils. The reduction of Cr(VI) was described by first-order kinetics at a significant level (p < 0.05) for the tested soils. The rate constant (k) of Cr(VI) reduction ranged from 0.01 to 4.21 day−1. In addition, the k value significantly increased with organic carbon (OC) and cation exchange capacity, but significantly decreased with increasing pH and dithionite-citrate-bicarbonate extractable Mn (Mnd). However, a predictive model using stepwise regression analysis indicated that the k value of the kinetics was controlled by OC, dissolved organic carbon (DOC), and Mnd, thereby identifying the complex interactions between Cr(VI) reduction and soil factors in the humid tropics.
Evaluation of Serological Markers in Alveolar Echinococcosis Emphasizing the Correlation of PET-CTI Tracer Uptake with RecEm18 and Echinococcus-Specific IgG

Human alveolar echinococcosis (AE), which is caused by the cestode Echinococcus (E.) multilocularis, is an epidemiologically relevant issue in modern medicine and still poses a diagnostic and therapeutic challenge. Since diagnosis mainly relies on imaging procedures and serological testing, we retrospectively and comparatively analyzed the performance of an Echinococcus IgG screening ELISA, whole serum IgE, and two specific confirmatory ELISA platforms using the defined E. multilocularis antigens Em2-Em18 (Em2+) and recombinant Em18 (recEm18). With special emphasis on the clinical usefulness of recEm18, we correlated the laboratory results with clinical characteristics and imaging findings in a large and well-characterized cohort of N = 124 AE patients, who were followed over several years after either surgical plus subsequent pharmacological treatment or pharmacotherapy alone. All patients had routinely received PET-CTI every two years. Our data reveal strong correlations for both Echinococcus IgG and recEm18 with tracer uptake in PET-CTI and parasitic lesion size and number, suggesting additional clinical usefulness of recEm18 for certain constellations only, while IgG and Em2+ still appear reasonable and sensitive screening methods for initial diagnosis of AE. With this study, we aim to contribute to further optimizing medical care of AE patients. For instance, it might be reasonable to consider the replacement of some PET-CTI follow-ups by imaging procedures with less radiation exposure or serological means alone. Further studies that clarify the correlation of serological markers with ultrasound criteria might be particularly useful, and further retrospective as well as prospective investigations are justified in this context.
Elliptical Ring Patch Antenna for X-Band Radar

This paper presents a simulated design of high performance elliptical ring Microstrip patch antenna at resonant frequency of 8 GHz for radar. Owing to its intrinsic geometry elliptical ring patch is found to be suitable candidate for designing high power, large gain and better efficiency conformal antennas for radar at X-band or even higher frequencies. Simulated antenna shows very high average gain of 7.5 dB for entire bandwidth of 340MHz i.e. 4.25% impedance bandwidth. Simulated results shows very good return loss performance, S11 parameter is -42.5 dB at resonant frequency. Roger Ultralam 2000 substrate is used to design the antenna. Average radiation efficiency of antenna is very high (97.9%). Design show great promise for radar application with no side lobes, high directivity of 7.71 dB at 8 GHz & very high front to back ratio. Comparative study of recent works in X-Band and our design is presented & variation of return loss with dielectric height is also elaborated in paper. Keywords—Elliptical Ring , Radar, X-band, High performance, high gain,Patch Antenna.
Impacts of Grazing by Small Ruminants on Hillslope Hydrological Processes: A Review of European Current Understanding

Unsustainable grazing of animals exerts pressure on a range of environmental factors. This review assessed the impacts of grazing of small ruminants (SRs; sheep and goats) on hydrological processes (e.g., runoff occurrence and erosion) within European pasture lands. It also considered other effects of SRs grazing, such as water pollution. Our research highlights the lack of evidence‐based European literature on the implications of grazing by SRs on the hydrological processes. The available literature is limited to the Mediterranean belt (some areas of Spain and Greece), the British Isles, and the Austrian Alps. The reasons behind the lack of literature are discussed in detail, and the knowledge gaps dealing with SRs have been enumerated. However, there are several articles on the subject within Oceania‐Pacifica and United States settings. Some of the reasons contributing to the limited literature on Europe are the possible underestimation of the significance of the problem, it being considered an unattractive research direction, and/or a lack of research funding. Thus, more research and funding are required to address the European knowledge gaps and limitations related to the impacts of grazing by SRs on the hydrological processes.
Cytotoxicity of Fenugreek Sprout and Seed Extracts and Their Bioactive Constituents on MCF-7 Breast Cancer Cells

Trigonella foenum-graecum L. (fenugreek), a member of the legume family (Fabaceae), is a promising source of bioactive phytochemicals, which explains its traditional use for a variety of metabolic disorders including cancer. The current study aimed to evaluate extracts of fenugreek seeds and sprouts, and some of their constituents, to compare their cytotoxic and antiproliferative activities in MCF-7 breast cancer cells. The extracts were chemically characterised using high-resolution accurate mass liquid chromatography-mass spectrometry to reveal the detection of compounds assigned as flavone C-glycosides including those derived from apigenin and luteolin, in addition to isoflavones. Five different flavones or their glycosides (apigenin, vicenin-2, vitexin, luteolin and orientin) and two isoflavones (daidzein and formononetin) were quantified in the fenugreek extracts. The 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide assay using MCF-7 cells treated with fenugreek methanolic extracts showed dose- and time-dependent effects on cell viability. The MCF-7 cancer cells treated with the fenugreek methanolic extracts also displayed increased relative mitochondrial DNA damage as well as suppressed metastasis and proliferation. This study demonstrates the potential anti-cancer effects of fenugreek seeds and sprouts and reveals fenugreek sprouts as an untapped resource for bioactive compounds.
The Analysis of Translated Hedges in Trump’s Political Speeches and Interviews

This study tackles the analysis of translated hedges, in Trump’s political speeches and, interviews in the data, which have taken from three different political interviews of press conferences; that have conducted with U.S. President Donald Trump about coronavirus with their translations into Arabic. Therefore, the study has adopted Fraser’s classification of hedges and tries to apply it into the data. Moreover, the study has applied statistics to find out that illocutionary force hedges have widely used in Trump’s political speeches and interviews more than the propositional hedges according to Fraser’s classification of hedges. Thus, hedges can be considered as one of the most important linguistic phenomena because it can widely be used as a way of expressing points of view in political discourse. In addition to that, this linguistic phenomenon can be used by variety speakers of people in their daily life such as doctors, teachers, lawyers, but in particular politicians in their speeches, TV-interviews and press-conferences.