Miracle-dz/UniFAR-FTUs huggingface dataset:
The contribution of participation in meaningful activities on mental health during the COVID-19 lockdown in the Spanish population

Introducción: Durante el confinamiento provocado por el COVID-19 en España, los ciudadanos tuvieron que dejar de realizar actividades de forma habitual, lo cual podría haber tenido un impacto en la salud mental. El objetivo de este estudio fue determinar la contribución de la participación en actividades significativas sobre la salud mental en la población española durante el confinamiento por COVID. Método: Se realizó una encuesta web de diseño transversal, donde se evaluó la salud mental (Cuestionario de Salud General: GHQ), la resiliencia (Escala de Resiliencia de Connor-Davidson), la participación en actividades significativas (Encuesta de Participación en Actividades Significativas), así como datos sociodemográficos. Se utilizó una regresión jerárquica-lineal para identificar las correlaciones clave. Resultados: Los participantes (N = 311) informaron de una baja salud mental (M = 16,12/36), y también de un menor nivel de resiliencia (M = 25,48). Los resultados de la regresión revelaron que el 32,6% de la varianza del GHQ se explicaba significativamente por la posibilidad de tener en la vivienda un espacio exterior, la resiliencia y la participación en actividades significativas. La pérdida de actividades significativas se relacionó significativamente con la salud mental, contribuyendo significativamente controlando las otras variables (β = -.12). Conclusiones: Aunque se necesitan estudios experimentales para determinar la causalidad, este estudio pone de manifiesto la relación entre la participación en actividades significativas y la salud mental durante el confinamiento. Introduction: During the lockdown caused by COVID-19 in Spain, citizens had to stop performing activities in the usual way, which could have had an impact on mental health. The aim of this study was to determine the contribution of participating in meaningful activities on mental health in the Spanish population during the COVID-19 lockdown. Method: A cross-sectional online survey was developed and administered, where mental health (General Health Questionnaire), resilience (Connor-Davidson Resilience Scale), participation in meaningful activities (Engagement in Meaningful Activities Survey) and socio-demographic data were assessed. A hierarchical-linear-regression was used to identify key correlations. Results: The participants (N = 311) reported low mental health (M = 16.12/36) and a lower level of resilience (M = 25.48). The results of the regression revealed that 32.6% of the variance of the GHQ was significantly explained by the living space, including an outdoor space, resilience and participation in meaningful activities. The loss of meaningful activities was significantly related to mental health, with a significant contribution when controlling for the other variables (β = -.12). Conclusion: Although experimental studies are needed to determine causality, this study highlights the relationship between participation in meaningful activities and mental health during the lockdown.
Pro-Neurogenic Potential of Daphne mucronata Royle

The petroleum ether soluble and insoluble fractions of the methanol extract of air dried stem extract of Daphne mucronata and a pure compound daphnin obtained from the more active petroleum ether insoluble fraction were evaluated for the pro-neurogenic activity on cortical and hippocampal primary cell cultures prepared from the neonatal mice brain. It showed significant proliferation of the cells as assessed by MTT assay
Modelling pyroclastic density currents of the April 2021 La Soufrière St. Vincent eruption: from rapid invasion maps to field-constrained numerical simulations

The April 2021 La Soufrière of St. Vincent eruption generated several pyroclastic density currents (PDCs) during the two weeks of the crisis, from April 9 th to April 22 nd . To support the hazard assessment team during this eruption, numerical simulations were performed in real time and generated rapid scenario-based PDC invasion maps with the two-phase version of the code VolcFlow, which was able to simulate both the concentrated and dilute regime of PDCs. To generate the maps, only the source properties (shape and location) and the initial volume used to generate the PDCs were varied, all other input parameters were kept constant and estimated from previous simulations. New simulations were then performed based on the field-based deposit map to assess the code's ability to simulate such PDCs. Results show that the syn-crisis invasion maps satisfactorily mimic the observed valley-confined PDCs, while unconfined dilute PDCs were overestimated. The result also highlight that simulation results are greatly improved with additional field-based data, which help constrain the PDC sequence. Numerous lessons were learned, including: (i) how to choose the most critical input parameters, (ii) the importance of syn-eruptive radar imagery, and (iii) the potential of this two-phase model for rapid hazard assessment purposes.
Comparing the Efficacy of Myo-Inositol Plus α-Lactalbumin vs. Myo-Inositol Alone on Reproductive and Metabolic Disturbances of Polycystic Ovary Syndrome

Despite the beneficial effect of myo-inositol on metabolic, hormonal, and reproductive parameters of polycystic ovary syndrome (PCOS) patients, 28% to 38% could be resistant to this treatment. The combination with the milk protein α-lactalbumin can be a useful therapeutic approach to overcome inositol resistance and achieve ovulation in these women. This open-label prospective study aimed to compare the effects of supplementing myo-inositol plus α-lactalbumin vs myo-inositol alone on reproductive and metabolic abnormalities in PCOS. A total of 50 anovulatory women with a PCOS diagnosis were randomly assigned to receive myo-inositol alone or a combination of myo-inositol and α-lactalbumin for three months. Anthropometric measures, hormonal levels, and menstrual cycle duration were collected at baseline and after treatment. The therapy with myo-inositol plus α-lactalbumin improved both ovulation rate and menstrual cycle duration more than myo-inositol alone. The body weight was significantly reduced in women receiving myo-inositol plus α-lactalbumin, while patients in the myo-inositol group experienced no change. In addition, the improvement of hyperandrogenism was more prominent in patients treated with myo-inositol plus α-lactalbumin. The benefits of associating myo-inositol and α-lactalbumin clearly make this combination a true edge in the management of PCOS.
Recent Trends in Lateral Flow Immunoassays with Optical Nanoparticles

Rapid, accurate, and convenient diagnosis is essential for effective disease management. Various detection methods, such as enzyme-linked immunosorbent assay, have been extensively used, with lateral flow immunoassay (LFIA) recently emerging as a major diagnostic tool. Nanoparticles (NPs) with characteristic optical properties are used as probes for LFIA, and researchers have presented various types of optical NPs with modified optical properties. Herein, we review the literature on LFIA with optical NPs for the detection of specific targets in the context of diagnostics.
Evaluation of raw milk quality from multipurpose cow in Jos, Nigeria

This study aimed to access the milk yield and quality of White Fulani and Sokoto Gudali cows in Jos North and South Local Government Areas of Plateau State Nigeria. A total of one hundred (100) respondents were interviewed and subsequently milk samples were collected for laboratory analysis, microbial quality assessment and milk composition. The results showed majority of the respondent were males of varying ages with 34% attaining secondary education. Moisture content, fat and nitrogen-free extracts were significant (P<0.05) between the two breeds while the other parameters were not significant (P>0.05). Total bacterial count (TBC) and Total coliform count (TCC) of White Fulani were higher in Jos North than south (3.8x 105 and 2.9x105) while Sokoto Gudali breeds had higher values of total bacterial counts in Jos North than Jos South. Bacillus spp, Escherichia and Webseilla aerogenes are the most dominant bacteria in White Fulani and Sokoto Gudali cows’ milk. This study concludes that poor quality of cow milk results from unhygienic practices and animal husbandry at farm level which predispose famers, consumers and the public to the risk of contracting milk borne zoonotic infection and associated bacterial resistance.
Contrasted root trait responses between saplings of an arbuscular and an ectomycorrhizal tree species in open field compared to forest conditions

Plant nutrient acquisition strategies range along a spectrum from autonomous foraging to investment in cooperative foraging through mycorrhizal associations. However, in temperate ecosystems, many plant species encounter contrasted levels of symbiont availability in open fields versus closed forests. Little is known about how fungal partner availability may be associated with intraspecific variation in other root foraging traits in natural settings. Here, we addressed this issue by sampling saplings from two tree species: the arbuscular mycorrhizal (AM) Acer rubrum and the ectomycorrhizal (ECM) Quercus rubra from open fields (AM dominated) and adjacent forest plots (ECM dominated). For each species and environment, we measured morphological, architectural and symbiotic root traits. For the open field, Quercus had greater specific root length (SRL) while Acer had higher AM colonization and root diameter. In the closed forest, the opposite pattern was observed, namely Quercus had higher ECM colonization and Acer greater SRL. Both species showed evidence of a shift towards autonomous root foraging in the habitat with low expected symbiont abundance (open field for Quercus and forest for Acer). Although the confounding effects of site abiotic properties could not be strictly controlled in this study, these results suggest that plants might adjust root foraging traits according to local habitat conditions. Synthesis: Our results shed new light on the intraspecific variation in plant position along the so‐called ‘collaboration gradient’, and suggest that mycorrhizal symbiont availability, along with other factors such as competition and site properties, may contribute to this variation.
The Exosome-like Vesicles of Giardia Assemblages A, B, and E Are Involved in the Delivering of Distinct Small RNA from Parasite to Parasite

The genetically related assemblages of the intestinal protozoa parasite Giardia lamblia are morphologically indistinguishable and are often derived from specific hosts. The Giardia assemblages are separated by large genetic distances, which might account for their relevant biological and pathogenic differences. In this work, we analyzed the RNAs cargo released into exosomal-like vesicles (ElVs) by the assemblages A and B, which differentially infect humans, and the assemblage E, which infects hoofed animals. The RNA sequencing analysis revealed that the ElVs of each assemblage contained distinct small RNA (sRNA) biotypes, suggesting a preference for specific packaging in each assemblage. These sRNAs were classified into three categories, ribosomal-small RNAs (rsRNAs), messenger-small RNAs (msRNAs), and transfer-small RNAs (tsRNAs), which may play a regulatory role in parasite communication and contribute to host-specificity and pathogenesis. Uptake experiments showed, for the first time, that ElVs were successfully internalized by the parasite trophozoites. Furthermore, we observed that the sRNAs contained inside these ElVs were first located below the plasma membrane but then distributed along the cytoplasm. Overall, the study provides new insights into the molecular mechanisms underlying the host-specificity and pathogenesis of G. lamblia and highlights the potential role of sRNAs in parasite communication and regulation.
Screening of promising rice varieties against rice weevil (Sitophilus oryzae) under laboratory condition

The varietal screening of S. oryzae was studied on the rice grain and it was revealed that the minimum number of adult emergence was found in variety Swarna (3.33 adults) whereas variety MTU-1001 was found to be tolerant against S. oryzae with less per cent of grain damage (2.66%) and weight loss (1.00%). While the variety Dubraj Selection -1 was found highly susceptible to this pest in accordance to highest number of adult emergence (21.65 adults), maximum percent of grain damage (8.33%) and weight loss (6.66%), respectively
The complete chloroplast genome of Corethrodendron multijugum (Fabaceae: Corethrodendron) and phylogenetic analysis

Abstract Corethrodendron multijugum (Maxim.) (Fabaceae: Corethrodendron), also known as Hedysarum multijugum, is an important medicinal plant and is widely used in traditional Chinese medicine. To better understand the diversity and phylogeny of C. multijugum and other Fabaceae species, we sequenced and annotated the complete chloroplast genome of C. multijugum using the Illumina HiSeq 2500 platform. This complete genome was 122,994 bp long, and encodes a total of 110 genes, including 76 protein-coding genes (PCGs), 30 transfer RNA genes (tRNAs), and four ribosomal RNA unit genes (rRNAs). The C. multijugum plastid with a G + C content of 34.5% presents a negative AT -skew (–0.002) and a positive GC -skew (0.032). Phylogenetic analysis revealed that C. multijugum is more closely related to Hedysarum petrovii. This study provides genetic resource information for the further study of Corethrodendron.
Finite Element Analysis to Examine the Mechanical Stimuli Distributions in the Hip with Cam Femoroacetabular Impingement

xiv 1.0 Introduction . 1 1.1 Motivation . 1 1.2 Thesis Statement. 2 1.3 Objectives and Conceptual Framework . 2 1.4 Relevance and Theoretical Framework . 4 2.0 Background . 5 2.1 Anatomy . 5 2.1.1 Bones . 5 2.1.2 Capsule . 7 2.1.3 Ligaments . 8 2.1.4 Motion . 9 2.2 History of FAI . 12 2.3 Types . 16 2.3. 1 Cam Impingement . 17 2.4 Associated Casualties . 20 2.4. 1 Indications . 21 2.5 Computational Modelling . 23
Efficacy and safety of the serratus anterior block compared to thoracic epidural analgesia in surgery: Systematic review and meta-analysis

Objectives: The objective of this study was to compare the efficacy and safety of serratus anterior plane block (SAPB) and thoracic epidural analgesia (TEA) in thoracic region surgery. Materials and Methods: We implemented a systematic search of PubMed, ScienceDirect, SCOPUS, and Web of Science and through gray literature for all randomized controlled trials that compared SAPB, a novel thoracic wall nerve block, and TEA in surgery. The evaluated outcomes included the Visual Analog Scale (VAS), hypotension, and postoperative nausea and vomiting (PONV). Review Manager, version 5.4. 1, was implemented for the analysis of statistics. Results: The pooled analysis included six trials that fulfilled the inclusion criteria. In total 384, surgery had received regional blocks (162 – SAPB and 163 – TEA). VAS did not differ significantly between SAPB and TEA, with a mean difference of 0.71, P = 0.08. PONV incidence did not differ significantly between SAPB and TEA (odds ratio = 0.25, P = 0.07). Hypotension incidence was lower in SAPB compared to TEA (odds ratio = 0.10, P = 0.0001). Conclusion: SAPB yielded comparable VAS with TEA in pain management of thoracic region surgery. The incidence of hypotension was lower in SAPB than in TEA. No difference in PONV incidence was observed. SAPB can be a viable alternative to TEA in thoracic region surgery.
Planar wideband circularly polarized metasurface-based antenna array

Abstract This paper presents a planar circularly polarized (CP) antenna array with a high-gain and wideband operation. The array is based on a sequentially rotated feeding network for a set of 2 × 2 CP metasurface-based antennas. The single element is a microstrip-line-fed slot antenna, which is coupled to a metasurface having 4 × 4 truncated corner square patches, to produce the CP radiation. The wideband characteristic of the design is obtained by a proper combination between the feeding network and the CP metasurface-based antennas. The proposed array, with an overall size of 50 × 50 × 2.032 mm3 (~1.60 × 1.60 × 0.065 λ0 at 9.6 GHz), has been fabricated and tested. The measurements resulted in an |S11| < –10 dB bandwidth of 7.88–12.0 GHz (41.45%) and a CP radiation bandwidth of 8.4–10.6 GHz (23.16%). In addition, the antenna yielded a broadside left-hand CP radiation with a peak gain of 13.5 dBic, a 3-dB gain bandwidth of 8.6–10.8 GHz (22.68%), and a radiation efficiency of >84%.
The 3q Oncogene SEC62 Predicts Response to Neoadjuvant Chemotherapy and Regulates Tumor Cell Migration in Triple Negative Breast Cancer

In the absence of targeted treatment options, neoadjuvant chemotherapy (NACT) is applied widely for triple-negative breast cancer (TNBC). Response to NACT is an important parameter predictive of oncological outcomes (progression-free and overall survival). An approach to the evaluation of predictive markers enabling therapy individualization is the identification of tumor driver genetic mutations. This study was conducted to investigate the role of SEC62, harbored at 3q26 and identified as a driver of breast cancer pathogenesis, in TNBC. We analyzed SEC62 expression in The Cancer Genome Atlas database, and immunohistologically investigated SEC62 expression in pre- and post-NACT tissue samples from 64 patients with TNBC treated at the Department of Gynecology and Obstetrics/Saarland University Hospital/Homburg between January 2010 and December 2018 and compared the effect of SEC62 on tumor cell migration and proliferation in functional assays. SEC62 expression dynamics correlated positively with the response to NACT (p ≤ 0.01) and oncological outcomes (p ≤ 0.01). SEC62 expression stimulated tumor cell migration (p ≤ 0.01). The study findings indicate that SEC62 is overexpressed in TNBC and serves as a predictive marker for the response to NACT, a prognostic marker for oncological outcomes, and a migration-stimulating oncogene in TNBC.
Fast Motion Estimation Using

Gradient-based motion estimation methods (GMs) are considered to be in the heart of state-of-the-art registration algorithms, being able to account for both pixel and subpixel registration and to handle various motion models (translation, rotation, affine, and projective). These methods estimate the mo- tion between two images based on the local changes in the image intensities while assuming image smoothness. This paper offers two main contributions. The first is enhancement of the GM tech- nique by introducing two new bidirectional formulations of the GM. These improve the convergence properties for large motions. The second is that we present an analytical convergence analysis of the GM and its properties. Experimental results demonstrate the applicability of these algorithms to real images.
Production and Properties of Quercetin-Loaded Liposomes and Their Influence on the Properties of Galactomannan-Based Films

The objective of this work was to prepare different concentrations of liposomes based on lecithin containing quercetin, and evaluate their effect on the properties of galactomannan films obtained from Cassia grandis seeds. Quercetin-loaded lecithin liposomes (QT-LL) were obtained by the ethanol injection method by incorporating quercetin in different concentrations in a previously prepared suspension of lecithin liposomes in water. Following characterization of QT-LLs by zeta potential and dynamic light scattering, QT-LL with 75 µg quercetin/mL suspension was incorporated at different concentrations in galactomannan films. The films obtained were characterized for color, solubility, moisture content (MC), water vapor permeability (WVP), scanning electron microscopy (SEM), X-ray diffraction (XRD), and Fourier-transform infrared (FTIR) spectroscopy. The size of lecithin liposomes with no quercetin was statistically than those containing quercetin above 50 µg/mL. All the QT-LLs presented a low polydispersity index, even considering their significant differences and similar values for zeta potential. The films displayed a rough surface and the galactomannan structure was confirmed by FTIR. Additionally, the amorphous nature of the polysaccharide was observed by XRD. The films were luminous, with a predominant yellow tendency and low opacity. The incorporation of QT-LL in galactomannan films did not lead to statistical differences for solubility and MC, while significant differences were observed for WVP. Galactomannan films were shown to be a promising structure for the incorporation of lecithin liposomes loaded with quercetin, pointing at promising applications for different applications.
Transition Prediction in Three-Dimensional Boundary-Layer Flows Unstable to Crossflow Instability

transition process dominated by crossflow instability is considered to explore the possibility of a more accurate transition prediction than the eN-method allows. It is demonstrated that the nonlinear development extends over the largest part of the transition process. A strong and complex dependence upon the initial conditions is established. Controlled experiments explain the underlying mechanisms. If the initial conditions are known, the disturbance growth can be predicted up to saturation using nonlinear PSE approaches. There is still some uncertainty regarding the process which initiates the final breakdown of laminar flow after the disturbances have saturated. The big remaining problem is the receptivity problem. Thereby the receptivity to surface roughness appears to be solvable whereas the receptivity to free stream turbulence can be modelled only by empirical methods at present.
Predicting Effortful Control at 3 Years of Age from Measures of Attention and Home Environment in Infancy: A Machine Learning Approach

Effortful control (EC) is a dimension of temperament that encompass individual differences in self-regulation and the control of reactivity. Much research suggests that EC has a strong foundation on the development of executive attention, but increasing evidence also shows a significant contribution of the rearing environment to individual differences in EC. The aim of the current study was to predict the development of EC at 36 months of age from early attentional and environmental measures taken in infancy using a machine learning approach. A sample of 78 infants participated in a longitudinal study running three waves of data collection at 6, 9, and 36 months of age. Attentional tasks were administered at 6 months of age, with two additional measures (i.e., one attentional measure and another self-restraint measure) being collected at 9 months of age. Parents reported household environment variables during wave 1, and their child’s EC at 36 months. A machine-learning algorithm was implemented to identify children with low EC scores at 36 months of age. An “attention only” model showed greater predictive sensitivity than the “environmental only” model. However, a model including both attentional and environmental variables was able to classify the groups (Low-EC vs. Average-to-High EC) with 100% accuracy. Sensitivity analyses indicate that socio-economic variables together with attention control processes at 6 months, and self-restraint capacity at 9 months, are the most important predictors of EC. Results suggest a foundational role of executive attention processes in the development of EC in complex interactions with household environments and provide a new tool to identify early markers of socio-emotional regulation development.