Miracle-dz/UniFAR-FTUs huggingface dataset:
The Effectiveness of Biacid (Organic Acid and Essential Oil) as Substitute for Antibiotics on Ileal Characteristics of Broilers

The research was aimed to evaluate the characteristics of ileal broiler with the inclusion of Biacid as feed additive on broiler feed. The material was used 900 DOC broiler with average body weight 45.34±4.403 g and coefficient of diversity 9.71 % and reared for 35 days. The method that used in the research was experiment using completely randomized design with 4 treatments and 5 replications. The feed treatments consisted of P0=basal feed without Biacid, P1=basal feed + Biacid 0.075 %, P2=basal feed + Biacid 0.100 %, and P3=basal feed + Biacid 0.125 %. The variables measured were villus number, villus height, villus surface area,and crypt depth. The data was analyzed use Analysis of Variance (ANOVA) and Duncan’s Multiple Range Test (DMRT). The result showed that the inclusion of Biacid had a significant effect (P<0.05) on villus high and crypt depth, but not significant effect (P>0.05) on villus number and villus surface area. The conclusion research that is addition 0.075 % Biacid give the best result from villus total, villus surface area, and crypt depth at level.
Escherichia coli 0157:H7 colonisation in cattle: mucosal pathology and immune responses

Escherichia coli 0157:H7 causes serious human disease including haemorrhagic colitis and haemolytic uraemic syndrome. Ruminants and in particular cattle are a reservoir of infection, though colonised animals are clinically asymptomatic. Recent research has established that the terminal rectum is the predominant colonisation site for enterohaemorrhagic E. coli 0157:H7 in cattle. Thus the main goals of the PhD project were to understand the carriage and persistence of E. coli 0157:H7 in the bovine host, through examination of faecal shedding patterns and gastrointestinal tract tissues in experimentally infected calves. A marked bacterial tropism for the terminal rectum was confirmed while other minor carriage sites were identified. E. coli 0157:H7 induced histopathological alterations of the rectal mucosa and cannot be considered as a commensal. The pathological changes included a local infiltration of neutrophils and production of rectal mucosal IgA responses against E. coli 0157:H7 antigens. The work presents evidence of strong local IgA immune responses directed against membrane protein components, Type Ill-secreted proteins, 0157 lipopolysaccharide and H7 flagellin. This study has sought to elucidate the specifc mucosal immune responses against E. coli 0157:H7 outer membrane porin C, and in particular, against the sections of the protein situated on the external surface of the bacterial membrane. While there were consistent immune responses against the whole membrane protein, purified peptides of the external areas of the porin failed to elicit detectable mucosal immune responses. The identification of pathological changes and local host responses to E. coli 0157:H7 colonisation of the
PENGARUH CAPITAL INTENSITY DAN DEFERRED TAX EXPENSE TERHADAP TAX AVOIDANCE DENGAN MENGGUNAKAN STRATEGI BISNIS SEBAGAI VARIABEL MODERASI

Tujuan dari penelitian ini untuk menguji hubungan antara capital intensity, deferred tax expense terhadap tax avoidance dengan strategi bisnis sebagai variabel pemoderasi. Populasi yang digunakan dalam penelitian ini adalah perusahaan consumer goods yang terdaftar di Bursa Efek Indonesia pada tahun 2014-2018. Pengambilan sampel dilakukan dengan mengunakan metode purposive sampling. Data tersebut dianalisis menggunakan analisis regresi berganda untuk mengetahui pengaruh antar variabel independen terhadap tax avoidance. Hasil dari penelitian ini adalah menunjukan bahwa capital intensity memiliki pengaruh positif terhadap tax avoidance dan deferred tax expense memiliki pengaruh negatif terhadap tax avoidance. Sedangkan strategi bisnis ditemukan tidak dapat menjadi variabel moderator untuk pengaruh deferred tax expense terhadap tax avoidance. Tetapi strategi bisnis dapat menjadi variabel moderator pada pengaruh variabel capital intensity terhadap tax avoidance.
Resetting Cell Fate by Epigenetic Reprogramming

Epigenetic modifications and their regulations govern the identity of every cell type in an organism. Cell differentiation involves a switch in gene expression profile that is accompanied by heritable changes of epigenetic signatures in the differentiated cell type. Differentiation is generally not reversible, thereby conferring cell fate decisions once an altered epigenetic pattern is set. Nevertheless, attempts have been made to reverse a dif - ferentiation cell fate to a pluripotent state by various experimental approaches, such as somatic cell nuclear transfer, cell fusion and ectopic expression of defined transcription factors. The fundamental basis of all these strategies is to mediate epigenetic reprogram ming, which allows a permanent and completed conversion of cell fate. A comprehensive understanding of the dynamic of epigenetic changes during cell differentiation would provide a more precise and efficient way of reprogramming cell fate. Here we summarize the epigenetic aspects of different reprogramming strategies and discuss the possible mechanisms underlying these epigenetic reprogramming events.
Assessment of growth hormone gene polymorphism effects on reproductive traits in Holstein dairy cattle in Tunisia

Abstract Research to assess the effect of single genes on reproductive traits in bovine species is imperative to elucidate genes' functions and acquire a better perspective of quantitative traits. The present study was undertaken to characterize genetic diversity in the bovine growth hormone (GH) gene in a population of 410 Holstein dairy cows in Tunisia. The analyses were based on single nucleotide polymorphisms, and GH-AluI and GH-MspI detections and genotyping were carried out using the polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) method. Data were analyzed using a mixed linear model with the MIXED procedure to reveal the possible effect of GH genotypes on reproductive traits. The frequency data of AluI(L//V) and MspI(+//-) alleles were 87.04//12.96 and 70.06//29.94, respectively. The distribution of the frequency of GH genotypes for LL/LV/VV and (-/-)//(+/-)//(+/+) were 77.75//18.59//3.66 and 15.37//29.13//55.50, respectively. The results of the statistical analyses proved that GH-AluI showed a substantial favorable effect on exanimate traits except for the age at first calving; however, only a suggestive effect of GH-MspI on the calving interval (CI) and the days open (DI) was found. The homozygous LL genotype seemed to be advantageous with respect to the CI and the DI compared with LV and VV genotypes. Heterozygous MspI(+/-) cows tended to have a longer CI and DI than MspI(+/+) and MspI(-/-) cows, but the difference was not statistically significant. A significant effect of different GH-AluI–MspI combined genotypes was found on the number of inseminations per conception, the CI and the DI, and the LL/– combined genotype seemed to be associated with better reproductive performance. Based on these results, the LL genotype of the GH locus can be considered to be a favorable genotype for reproductive traits in Holstein dairy cattle, although these findings need to be confirmed by further research before polymorphisms can be used in a marker-assisted selection program.
Improvement Salt Tolerance of Safflower Plants by Endophytic Bacteria

Salinity is one of the most dangerous environmental limiting factors of the plant productivity. A wide range of adaptation strategies is required to overcome salinity stress. However, such strategies seem to be long drawn and cost-intensive. It has been confirmed in recent years that plant growth promoting endophytes (PGPEs) that have the ability to further build a symbiotic association with their host to improve host plant salt tolerance. In our investigation try to improve plant salt tolerance using different species of endophytic bacteria. From the total eight endophytic bacterial species were isolated from root, stem, and leaf of Carthamustinctorius (safflower) plant, two isolates were capable of using 1-aminocyclopropane-1-carboxylic acid (ACC) as a sole nitrogen source, and they are of positive results for (ACC) deaminase activity and indole-3-acetic acid (IAA) production. The bacterial isolates were identified using 16S ribosomal DNA technique as Bacillus cereus and Bacillus aerius and had accession numbers MG708176 and MG711593 respectively, by submitting their sequences in GenBank database. This study showed that the bacterial strains B. cereus and B. aerius are valuable biological plant growth promoters that could enhance salt tolerance in Safflower plants under 100, 200, and 300mMNaCl levels resulting in an increase in plant growth and ascorbate-glutathione redox cycle, in comparison with the non-inoculated controls. Our findings reported that the co-inoculation of the two selected endophytic bacteria strains were successfully isolated from Safflower seedlings significantly alleviated the harmful effects of salt stress, promoted plant growth and biomass yield.
Western wood species treated with chromated copper arsenate : effect of moisture content

The effect of wood moisture content on treatability with chromated copper arsenate was examined for western hemlock, mountain hemlock, grand fir, white fir, noble fir, Pacific silver fir, and Douglas-fir lumber. Samples were removed over the course of drying, their moisture contents were determined, and the samples were treated with chromated copper arsenate by a full-cell process. Treatment of samples from individual boards varied widely, reflecting the inherent variations in treatability found in these species. Comparisons between rate of drying and treatability for individual boards suggested that sorting by drying rate could be used to improve treatment for western hemlock and grand fir. The implications of these findings are discussed with regard to current practices and commercial feasibility.
Augmented Reality (AR) based application to introduce animals for children

The development of technology today is very helpful in the multimedia-based learning process. Children will be more interested in learning if the application can be installed on a Smartphone, because children enjoy playing Smartphones. In teaching children to recognize animals, teachers at school use pictures. With the presence of multimedia based on Augmented Reality (AR), it is helpful for displaying images of animals in 3-dimensional form so it is more interesting. Applications created can help children to classify, explain about animals through information about sounds, habitat, breeding about animals in the form of 3D objects. In making Augmented Reality Animal Recognition, the researcher adopted the SDLC (System Development Life Cycle) method. At the trial stage, the Alpha version of the application was carried out to determine the quality, shortcomings and smoothness of the application that had been made. Application test results could run well. Therefore, through this application, children are more interested in getting to know animals so that it provides a learning experience and is easily accessible on smart phones.
An assessment of long-term monitoring data for constructed wetlands for urban highway runoff control

Constructed wetlands have gained acceptance as a means of treating stormwater runoff from urban developments. Much of the available data regarding the performance of these facilities is based upon monitoring conducted over the course of less than two years, and as such inherently assumes that the period of analysis represents the "typical" or "design" conditions under which these facilities are intended to operate. While this information has provided guidance regarding the mechanisms by which wetlands provide quality treatment of urban runoff, it does not fully reflect the variability of conditions under which the facilities operate over the fullness of time, which is of particular concern to designers and operators. The construction of the Dartnall Road Interchange, as part of Hamilton's Lincoln Alexander Parkway, required a monitoring program-which included five years of water quality sampling-as a condition of approval by the Department of Fisheries and Oceans. This paper reports on the quantitative and qualitative wetland water quality monitoring data (sediment, nutrients, metals) obtained over the course of a total seven-year program, and provides information regarding the operating conditions and estimates on contaminant removal efficiencies from the facilities.
Anosognosia for hemiplegia as a tripartite disconnection syndrome

The rare syndrome of Anosognosia for Hemiplegia (AHP) can provide unique insights into the neurocognitive processes of motor awareness. Yet, prior studies have only explored predominately discreet lesions. Using advanced structural neuroimaging methods in 174 patients with a right-hemisphere stroke, we were able to identify three neural networks that contribute to AHP, when disconnected: the (1) premotor loop (2) limbic system, and (3) ventral attention network. Our results suggest that human motor awareness is contingent on the joint contribution of these three systems.
Guidance from the Scientific and Standardization Committee for lupus anticoagulant/antiphospholipid antibodies of the International Society on Thrombosis and Haemostasis

This guidance focuses on methodological aspects of lupus anticoagulant (LA) testing, as well as interpretation of results for clinicians. The main changes in how to test for LA compared with the International Society on Thrombosis and Haemostasis Scientific and Standardization Committee 2009 guidelines, in the preanalytical phase are more detailed recommendations on how to handle testing in anticoagulated patients, and the timing of testing. Also, routine coagulation tests are advised to obtain more information on the coagulation background of the patient, and when necessary, anti‐Xa activity measurement for heparins or specific assays for direct oral anticoagulants should be performed. The three‐step procedure with two test systems (diluted Russell's viper venom time and activated partial thromboplastin time [aPTT]) is essentially not changed. Silica remains the preferable activator in the aPTT assays, but ellagic acid is not excluded. We advise simultaneous performance of the mixing and confirmatory step, in each sample with a prolonged screening test. The confirmatory step can also be performed on a mixture of patient plasma and normal pooled plasma. Cutoff values should be established in‐house on at least 120 normals, with transference of the manufacturer's cutoffs as an alternative. Reporting of results has not been changed, although more attention is focused on what clinicians should know. Patient selection for LA testing has been expanded.
Insecticide usage Pattern against Helicoverpa armigera (Hubner) in Karnataka State, India

Helicoverpa armigera Hubner (Noctuidae: Lepidoptera) is a widely distributed insect pest in Europe, Africa, Asia and South Pacific regions. The currently noticed global distribution of H. armigera suggests that the pest may be most closely associated with deserts and xeric shrub lands; Mediterranean scrub; temperate broadleaf and mixed forests; tropical and subtropical grasslands, savannas, and shrub lands; and tropical and subtropical moist broadleaf forest (Wasihun, 2016). It has a wide host range of over 360 plant species that includes most crop hosts are tomato, cotton, pigeonpea, chickpea, sorghum and cowpea and other hosts dianthus, rosa, pelargonium, chrysanthemum, groundnut, okra, peas, field beans, soybeans, lucerne, Phaseolus spp, tobacco, potatoes, maize, flax, a number of fruits (Prunus, Citrus), forest trees and a range of vegetable crops (Multani and Sohi, 2002; CAB, 2006).
Notch Signaling Pathway: An Emerging Therapeutic Target for African-American Triple Negative Breast Cancer Patients

The most fatal form of breast cancer, triple negative (TNBC), continues to challenge clinicians worldwide with its lack of reliable prognostic biomarkers and pharmacologically actionable treatment targets. In the US, this aggressive disease disproportionately afflicts African-American (AA) women at a rate 2-3 times higher than European-American (EA) women, thereby contributing to the observed higher mortality rates of AA BC patients. In order to address the unmet clinical need for new and effective treatments for AA TNBCs, we describe herein a potentially actionable pathway that appears to be in overdrive in TNBCs of AA patients compared to EA TNBCs: the Notch signaling pathway. Notch signaling is implicated in multiple aspects of carcinogenesis and tumor progression including in regulation of proliferation, apoptosis, the biology of cancer stem cells, tumor angiogenesis and epithelial-to-mesenchymal transition. Our gene expression analyses uncover significant upregulation of Notch signaling as well as gene ontologies reflecting dysregulation of key processes regulated by Notch signaling among AA compared to EA TNBC patients. Furthermore, we present evidence suggesting that upregulated Notch signaling may predict poor prognosis in TNBC. Our findings thus suggest differences in Notch signaling among racially-distinct TNBC patients that may contribute to the more aggressive clinical behavior of TNBC in AAs. These observations also suggest that Notch signaling may be an attractive therapeutic target for high-risk AA TNBC patients.
The functional outcome of operative management of displaced tibial plateau fracture

With improvement in imaging modalities like CT and MRI complex fracture patterns and soft tissue injuries were recognized. CT has been shown to help surgical planning and to lead to more reliability in classifying the fracture and deciding on a treatment plan. Patients were informed about the study in all respects and written informed consent will be obtained. The follow up period was 6 weeks, 3 months, 6 months, 41/2 months, 6 months, 9 months, 1 year and 2 years. In the present study on evaluation of the type of plates used, we found that of the 50 cases in the study, single plate was used in 34 patients (68%) and double plate used in 16 patients (32%). In the present study on evaluation of the final outcome of the fracture according to lysholm scoring scale most patients had excellent results (24 patients, 48%). Postoperative rehabilitation protocol in terms of non-weight bearing and achieving satisfactory range of motion needs to be strictly adhered to, in order to obtain optimal functional results. In our study we found that proximal tibial locking plates provides complete union and early mobilisation to attain better functional outcome.
Statistical analysis for genotype stability and adaptability in maize yield based on environment and genotype interaction models

Current analysis investigates genotype x environment interaction and stability performance of grain yield with nine maize genotypes in seven environments. ANOVA revealed highly significant (p-value<0.001) data for genotypes, environments and their interactions. Only PC1 (45.4%) and PC2 (35%) were significant (p ≤ 0.05). Genotype G7 had a specific adaptation to environment E7, whereas genotypes G2 and G3 were adapted to environment E1, and genotypes G8 and G9 to environment E5. Dataset was divided into group A, composed of E5 and E7, and group B composed of E1, E2, E3 and E6. Genotypes G1, G2, G3 and G6, belonging to group B, were the most productive. Further, no environment fell into the G4, G5, G7, G8 and G9 sectors, denoting these genotypes as the poorest ones across environments. GGE biplot indicated that genotype G4 was highly unstable, whereas G3 very stable. In addition, G2 was more desirable due to its small contribution to both G and GE. On the other hand, G4 and G9 were more undesirable due to large contribution to either G or GE. Finally, genotypes G2 and G9 were very different. Their dissimilarity may be due to difference in mean yield and/or in GEI.
Determinants of mobile health application awareness and use in India: an empirical analysis

Purpose - To examine the influence of mobile health in improving health service delivery in India. With this aim, the current research examines the role of individuals' cognitive factors, characteristics of mobile-service, and health-related behaviour from a technology viewpoint towards awareness and use of mobile health applications. Design/methodology/approach -Quantitative approach has been used with data being collected both online and offline through structured questionnaires. The factors for determining variables for awareness and use were prepared based on technology acceptance and health belief literature. A sample size of 528 responses was analysed using structural equation modelling. Findings - Mobile service enabled empowerment and health information orientation were found to have a direct influence on awareness and use. Originality/value -Earlier studies on mobile health relating to India explains its importance in health service delivery and were adequate in explaining individuals' cognitive factors, characteristics of mobile-service, and health-related behaviour from a technology viewpoint on awareness and use. Therefore, the current study attempts to establish relationships between these factors for measuring awareness and use. Drawing on the statistical inferences, the implication has been recommended.
Reduced chromatin accessibility underlies gene expression differences in homologous chromosome arms of hexaploid wheat and diploid Aegilops tauschii

Polyploidy has been centrally important in driving the evolution of plants, and leads to alterations in gene expression that are thought to underlie the emergence of new traits. Despite the common occurrence of these global patterns of altered gene expression in polyploids, the mechanisms involved are not well understood. Using a precise framework of highly conserved syntenic genes on hexaploid wheat chromosome 3DL and its progenitor 3L chromosome arm of diploid Aegilops tauschii, we show that 70% of these genes exhibited proportionally reduced gene expression, in which expression in the hexaploid context of the 3DL genes was approximately 40% of the levels observed in diploid Ae. tauschii. Many genes showing elevated expression during later stages of grain development in wheat compared to Ae. tauschii. Gene sequence and methylation differences accounted for only a few cases of differences in gene expression. In contrast, large scale patterns of reduced chromatin accessibility of genes in the hexaploid chromosome arm compared to its diploid progenitor were correlated with observed overall reduction in gene expression and differential gene expression. Therefore, that an overall reduction in accessible chromatin underlies the major differences in gene expression that results from polyploidization.
Two new phases in the system cobalt-tin : The crystal structures of α- and β-CoSn3

The tin-rich portion of the binary system cobalt-tin was reinvestigated and the existence of the new dimorphic compound CoSn 3 was established. The high-temperature β-phase is formed peritectically by reaction of CoSn 2 with the tin-rich melt at 345±2°C. The low-temperature α modification is stable below 275±5°C. Single crystals of both modifications were obtained from samples with excess of tin by dissolving the tin-rich matrix in diluted hydrochloric acid. Their crystal structures were determined from single-crystal X-ray diffractometer data ; β-CoSn 3 : I4 1 /acd, a = 627.5(1) pm, c = 3374(1) pm, Z = 16, R = 0.017 for 557 structure factors and 21 variable parameters; α-CoSn 3 : Cmca, a = 1686.4(3) pm, b = 626.8(1) pm, c = 627.0(2) pm, Z = 8, R = 0.035 for 401 F values and 22 variables. The β modification represents a new structure type, while α-CoSn 3 is isotypic with PdSn 3 . The two structures are stacking variants of each other. The β modification is a metallic conductor and Pauli paramagnetic.