Miracle-dz/UniFAR-FTUs huggingface dataset:
Physiological and Psychological Effects of Listening To Holy Quran Recitation in the Intensive Care Unit Patients: A Systematic Review

Stress and anxiety are common among intensive care unit (ICU) patients especially those who are on mechanical ventilation. Non-pharmacological interventions such as music and prayer are recommended because they are opioid sparing, easy to provide, cheap and safe. There is a growing body of evidence on the effects of Holy Quran Recitation (HQR) in reducing stress and anxiety in critically ill Muslim patients. The aim of this review is to evaluate the physiological and psychological effects of HQR specifically in ICU setting. This review was performed on articles published between 2007 and 2018. Extensive search was done using PubMed, ISI Web of Knowledge, Scopus and Google Scholar. Systematic review articles are also assessed and relevant literatures are hand searched based on reference lists and citations made in key publications. Studies related to HQR which were done outside adult ICU setting were excluded. A total of nine articles are included in the final list for detail analysis. Findings of this review revealed six studies with significant results in improving stress responses, hemodynamic stability and conscious levels. HQR is a potential nonpharmacological tool to reduce stress and can also be used as auditory stimulus to improve conscious level in comatose patients. More studies in this area are recommended aiming for low risk of bias, appropriate calculation of sample size and adequately powered to detect significant outcomes.
Digital Game's Impacts on Students' Learning Effectiveness of Correct Medication.

In recent years, considerable concern has arisen over the use of digital games as instructional tools in educational research. However, game-based learning not only enhances students’ learning motivation and effectiveness, but also fosters knowledge transfer. Taiwanese people living in rural areas often receive health-related information through television and radio advertisements. However, a lack of correct information leads to incorrect medication usage. Therefore, the purpose of this study is the practical development of a digital game related to correct medication usage. The technology acceptance model was applied to examine the impact of the game-based learning experience. The results showed that the post-test scores for correct medication usage were significantly higher than those obtained in the pre-test and indicated that the digital game could enhance students’ learning effectiveness. In addition, perceived ease of use and usefulness had significant impacts on attitude toward the correct medication usage digital game. In conclusion, game-based learning significantly enhanced students’ knowledge and abilities related to the correct usage of medication.
Diagrams Considering Well Resistance for Designing Spacing Ratio of Gravel Drains

ABSTRACT The finite difference method is applied to numerical analysis of the effectiveness of gravel drains constructed to prevent liquefaction of sandy soils due to earthquake motion. The basic equation used here is the axisymmetric diffusion equation which includes the generation of excess pore water pressure. The arcsin function of the equivalent cycle ratio formulated by Seed and Booker is used as the pore pressure buildup curve under undrained conditions. A comparison with the results of in-situ experiments reveals that the well resistance of the drain wells should be considered in the gravel drain design, and that the numerical method is valid for the pore pressure prediction. The analytical results are summarized as a set of diagrams in order to provide a convenient basis for the drain spacing design which takes well resistance into account. These diagrams permit drain spacing to be directly decided without the need for a computer. The application range of these diagrams is markedly wider than those of several existing diagrams currently used.
Influence of Bulb Weight at Planting and Drought Stress on Growth and Development of onion (Allium cepa L.) in the Northern Region of Ghana

Aims: To determine the effects of drought and bulb weight at planting on growth and development of onion in the Northern Region of Ghana. Study Design:Levels of bulb weights at planting and watering regimes were factorially combined and replicated three times in randomised complete block design. Place and Duration of Study:The study was conducted at the plant house of the University for Development Stu dies, Nyankpala in the Northern Region of Ghana from the 15 th of July to 30 th
Pre-Neogene basement rocks beneath the Kanto Plain, central Japan

17,200kmに達する日本最大の平野である. この平野は世界 でもユニークな存在である海溝-海溝-海溝型三重会合点に 隣接し,また東北本州弧と西南本州弧,さらには伊豆-小笠 原弧の接合境界に位置する. したがって,関東地方を含む中 央日本には,複数のプレートの相互運動が地層の変形や分布 様式に記録されていると考えられる. しかしながら,島弧会 合域である関東地方のかなりの範囲は関東平野が占め,先新 第三系の構造は厚い新第三系・第四系により覆い隠されてい る. 三重会合点のテクトニクスを復元するためには,まず西 南日本と東北日本の先新第三系における地体構造が,関東平 野の地下でどのように連続するのかを明らかにする必要があ る. 関東平野の地下における基盤構造は,深層ボーリングおよ び物理探査のデータによって推定されている. 石油および天 然ガス資源の開発を目的とした調査は戦前から行われてお り,1950年代からはとくに層序ボーリングや物理探査が活 発に行われた. その結果,関東平野には基盤深度が 3,000 m を超えるような地域が局所的に分布しており,基盤の大きな 深度差をもたらす伏在断層(烏山-菅生沼断層など)の存在 が推定された(石井, 1962; 畠山, 1964). 1970年代になる と,都市防災を目的とした大深度の地震観測井や地下水観測 は じ め に 井が多数敷設され,地下に分布する堆積層や基盤岩類の物性 に関する新たなデータが提供された(例えば, 高橋ほか, 1983). その結果,関東平野の地下には関東山地と同様,三 波川帯・秩父帯および四万十帯等の地体構造が大局的には北 西-南東方向に連続しているものと理解されるようになった (福田ほか, 1974; 矢島, 1981; 福田・鈴木, 1987). また,重 力異常や磁気異常のデータに基づき,関東平野を東西に横切 る中央構造線(MTL)や,それと東北日本における棚倉構 造線との関係が議論された(小川ほか, 1979; 長谷川, 1988; 駒沢・長谷川, 1988). 1990年代以降は 2,000 m級の地震観 測井が多数掘削され(鈴木, 1996, 2002; 鈴木・小村, 1999), また国立研究所や大学,自治体による地震探査が平野の全域 で行われるようになった(纐纈, 1995; 笠原, 2001). これらの 物理探査やボーリング調査によって,関東平野の地下に分布 する中新統は,基盤深度が特に大きい東京湾北部地域や利根 川低地,鬼怒川低地といった地域に偏在していることが明ら かにされた(鈴木, 2002; 林ほか, 2004c). こうした平野地下 における堆積層分布の偏りは,その基盤である先新第三系の 地体構造をある程度反映しているものと推定される. 関東平野には日本の政治および経済活動の中枢が位置して いるだけでなく,日本の総人口の 1/3近くが居住している. 平野の地下に分布する厚い新第三系は,地震波の増幅や長周 期の後続波を励起することによって,大地震発生時の強震動 分布に大きな影響を与えることが想定される(纐纈, 1995). 地質学雑誌 第 112巻 第 1号 2-13ページ,2006年 1月 Jour. Geol. Soc. Japan, Vol. 112, No. 1, p. 2-13, January 2006
Neonatal Sepsis : Looking Beyond the Blood Culture Evaluation of a Study of Universal Primer Polymerase Chain Reaction for Identification of Neonatal Sepsis

D IFFERENTIATING BACTERIAL SEPSIS FROM other conditions common in infants in the neonatal intensive care unit poses a number of challenges. First, clinical signs such as apnea, feeding intolerance, and need for increased respiratory support are nonspecific but still of concern for bacterial sepsis. These signs often prompt evaluation for sepsis that includes blood culture and antibiotic therapy for up to 48 hours while awaiting blood culture results. Second, blood culture accuracy may be decreased in neonates exposed to antibiotic agents during labor. Third, in some instances, a blood culture cannot be obtained before the initiation of antibiotic therapy. A test that could enable quick and accurate diagnosis of bacterial sepsis in these situations could avert unnecessary antibiotic therapy. To date, others tests such as white blood cell count, absolute neutrophil count, and C-reactive protein (CRP) level have not proved sufficiently accurate to justify withholding initial antibiotic therapy. In addition, no available test can enable accurate diagnosis of bacterial sepsis in neonates exposed to antibiotic agents before collection of blood for culture. Universal primer polymerase chain reaction (PCR) has been suggested as a potentially useful test in the diagnosis of neonatal sepsis in these settings.
Structure-activity relationships for thyroid hormone deiodination by mammalian type I iodothyronine deiodinases.

The bioactivity of thyroid hormone is determined to a large extent by the monodeiodination of the prohormone T4 by the hepatic selenoenzyme type I iodothyronine deiodinase (IDI), i.e. by outer ring deiodination (ORD) to the active hormone T3' or by inner ring deiodination (IRD) to the inactive metabolite rT3. IDI also catalyzes the IRD of T3 and the ORD of rT3' both to T2, as well as the deiodination of different iodothyronine sulfates, e.g. IRD of T3S and ORD of T2S. Previous studies have indicated important differences in catalytic specificity between dog IDI (dID1) and human ID1 (hID1), in particular with respect to the ORD of rT3. This study was done to investigate the relationship between structure and catalytic function of this enzyme by comparing the deiodination of T4, T3, rT3, T3S, and T2S by native dID1 and hID1 in liver microsomes as well as by recombinant wild-type, chimeric and mutated d/hID1 enzymes expressed in HEK293 cells. With both native and recombinant wild-type enzymes, the substrate specificity was T3S > T2S approximately rT3 approximately T4 > T3 for dID1, and rT3 > > T2S approximately T3S > T4 approximately T3 for hID1. Whereas ORD of T4 and of T4, T3, and T3S showed relatively little variation between the different d/hID1 constructs, large differences were found for the ORD of rT3 and T2S. Both reactions were favored by the presence of the amino acids G, E and, in particular, F, present in hID1 at positions 45, 46, and 65, instead of the dID1 residues N, G, and L, respectively. However, although ORD of rT3 was not affected by the presence (hID1) or absence (dID1) of the TGMTR(48-52) sequence, the ORD of T2S was markedly inhibited by the presence of this sequence. Therefore, we have identified structural elements in ID1 that have substrate-specific impacts on deiodination. Our results suggest the specific interaction of the mono-substituted inner ring of the substrates rT3 and T2S but not the disubstituted inner ring of T3, T3S, or T4, with the aromatic ring of F65 in Id1, perhaps by pi-pi interactions.
Onset of fast ice flow in Recovery Ice Stream, East Antarctica: a comparison of potential causes

Recovery Ice Stream has multiple branches reaching far into the East Antarctic ice sheet. We use new airborne and ground-based geophysics to give the first comprehensive overview of the upper catchment and, by constraining the physical setting, to advance our understanding of the controlling mechanisms for the onset of fast flow. The 400 km wide ice stream extends towards the Recovery Subglacial Lakes, a region characterized by a crustal boundary, a change in bed roughness, a bedrock topographic step and four topographic basins (A–D), three of which (A–C) contain subglacial water. All these characteristics are considered potential causal mechanisms that contribute to the onset of fast flow. In Lakes B and C the subglacial water is located in basins with sharp downstream ridges, in contrast to the gently sloping ridge on the downstream margin of Lake A. The fastest-flowing branch of the ice stream emanates from Lake A. The presence of multiple causal mechanisms along the four Recovery Lakes allows us to identify basal water as a dominant factor for the onset of fast flow, but only if it is stored in a shallow-sided basin where it can lubricate the flow downstream. Relatively minor topographic barriers appear to inhibit streaming.
Experimental evaluation of the effect of recycled cross-linked polyethylene on the performance of grouted macadam mixtures

ABSTRACT Grouted Macadam (GM) mixtures – recognized as semi-flexible pavement (SFP) materials – offer strong stability in high temperatures, good durability and high load-bearing capacity. However, these materials are prone to environmental and traffic-induced cracking. Cross-linked polyethylene (XLPE), a common high-voltage cable insulation, faces disposal challenges due to limited recycling technology, often leading to burning or burial of these waste materials. In this study, to enhance GM mixture crack resistance and mitigate the environmental impact of XLPE waste accumulation, XLPE material was used in GM mixtures in two methods. In the first group, 15%, 30%, and 45% of 4.75 to 9.5 mm natural aggregates were replaced in volume, with XLPE pseudo-aggregates of the same size. In the second group, XLPE pseudo-fibers (1.9–2.2 cm in length, 1.5 mm thickness) were incorporated as additives in 0.5, 0.7, and 1 volume percentages. The results of mechanical tests on treated GM mixtures showed that adding recycled XLPE improved durability, with a 24.5% and 29.9% enhancement in samples with the most pseudo-aggregates and pseudo-fibers contents. The fracture strain tolerance (FST) index in low-temperature bending tests also increased by 53.8% and 108.9% in mixtures containing XLPE, highlighting its potential to enhance GM mixture performance in various service conditions.
On semi-automated matching and integration of database schemas

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Poststroke Depression: A Scientific Statement for Healthcare Professionals From the American Heart Association/American Stroke Association

Depression occurs in approximately one third of stroke survivors at any one time and is associated with poor functional outcomes and higher mortality. Although poststroke depression (PSD) is one of the most common complications after stroke, few guidelines exist regarding assessment, treatment, and prevention of PSD. This scientific statement summarizes published evidence on the causes, predisposing factors, epidemiology, screening, treatment, and prevention of PSD; illuminates gaps in the literature; and provides management implications for clinical practice.
Fatigue crack initiation and propagation in lotus-type porous material

The investigation of fatigue strength of lotus-type structure with nodular cast iron as a base material using computational model is analysed in present study. The irregular pores distribution in transversal and longitudinal direction, regarding the external loading, is considered in the computational models. The complete fatigue process of analyzed porous structure is then divided into the crack initiation (Ni) and crack propagation (Np) period where the total fatigue life (N) is defined as: N = Ni + Np. The crack initiation period is determined using strain life approach where elastic-plastic numerical analysis is performed to obtain the total strain amplitude in the critical stress fields around the pores. The simplified universal slope method is then used to determine the number of stress cycles, Ni, required for formation of initial cracks. The number of stress cycles, Np, required for crack propagation from initial to the critical crack length is also numerically determined using finite element (FE) models, in the frame of Abaqus computation FEM code. The maximum tensile stress (MTS) criterion is considered when analyzing the crack path inside the porous structure. The performed computational analyses show that stress concentrations around individual pores are higher when external loading is acting in transversal direction in respect to the pore distribution. Therefore, further computational analyses regarding crack initiation and crack propagation period have been done only for pores distribution in transversal direction.
Estimation of Flow-Duration Curves at Ungaged Sites in Southern New England

Two sets of regional-regression equations are developed to estimate the daily, unregulated, period-of-record flow duration curve (FDC) at ungaged sites in southern New England. The first method assumes an underlying probability density function (pdf) for daily streamflow whose parameter values are related to the physical characteristics of the ungaged basin. The second method relates flow at selected exceedence probabilities on the FDC to physical characteristics of the ungaged basin. We consider 66 relatively unregulated gages having between 10 and 86 years of continuous, daily-streamflow measurements. A jack-knife procedure is used to compare FDCs estimated from each method to the gage data from which the regression equations were developed. FDC estimates from regression equations developed for individual exceedences led to lower mean square errors than estimates of FDCs that assumed an underlying pdf. L-moment diagrams, probability plots and simulation experiments reveal that daily streamflow are well approximated by a kappa distribution. The first four L-moments are highly correlated with each other, which were used to improve estimates of FDCs based on a regional kappa distribution.
Activity as a Mediator Between Users and Their Auditory Environment in an Urban Pocket Park

Sound is receiving increasing attention in urban planning and design due to its effects on human health and quality of life. Soundscape researchers have sought ecologically valid measures to describe and explain the complex relationship between people and their auditory environments, largely employing laboratory studies and neglecting the active role of activity. This chapter proposes a situated cognition approach to study the relationship between context, use of space, and the ways in which users describe and evaluate sounds and their auditory environments in an urban pocket park. It draws on empirical data gathered in Parc du Portugal in Montreal, Canada using a mixed-methods research design that integrates ethnographic observations, on-site questionnaires, and behavioral mapping using a geo-spatial app to offer a situated understanding of the human auditory experience in its full complexity, with an emphasis on the mediating role of activity on the user-auditory environment relationship.
The Health Risk Assessment of Groundwater Organic Pollution at a Certain Oil Depot

Based on the evaluation method for health risks of contaminated sites recommended by USEPA,in combination with the actual situation of the contaminated site,the authors analyzed and evaluated the health risk of groundwater organic pollution at a certain oil depot.The result shows that the organic pollutants in groundwater of the oil depot include 1,2-dichloroethane,benzene,chloroform and toluene.The non-carcinogenic risk suffered by the workers and residents in the contaminated site is less than 1,which is in the acceptable range.Nevertheless,the workers and residents in the contaminated site suffered a relatively high cancer risk,being 1.7×10-4 and 9.0×10-3,respectively,which are unacceptable.The 1,2-dichloroethane is a major pollutant of carcinogenic risk,accounting for 99.80% of the total cancer risk.It may cause many forms of cancer,and has the potential genetic toxicity.The main exposure way is the inhalation absorption,which accounts for more than 70% of the total cancer risk,followed by oral absorption.The carcinogenic risk via the dermal pathway is negligible,which is less than 1% of the total cancer risk.
USE IT OR LOSE IT : PROACTIVE , DETERMINISTIC LONGEVITY

Ever since the VLSI process technology crossed the sub-micron threshold, there is an increased interest in design of fault-tolerant systems to mitigate the wearout of transistors. Hot Carrier Injection (HCI) and Negative Bias Temperature Instability (NBTI) are two prominent usage based transistor degradation mechanisms in the deep sub-micron process technologies. This wearout of transistors can lead to timing violations along the critical paths which will eventually lead to permanent failures of the chip. While there have been many studies which concentrate on decreasing the wearout in a single core, the failure of an individual core need not be catastrophic in the context of Chip Multi-Processors (CMPs). However, a failure in the interconnect in these CMPs can lead to the failure of entire chip as it could lead to protocol-level deadlocks, or even partition away vital components such as the memory controller or other critical I/O. Analysis of HCI and NBTI stresses caused by real workloads on interconnect microachitecture shows that wearout in the CMP on-chip interconnect is correlated with lack of load observed in the network-on-chip routers. It is proven that exercising the wearout-sensitive components of routers under low load with random inputs can decelerate the NBTI wearout. In this work, we propose a novel deterministic approach for the generation of appropriate exercise mode data to maximize the life-time improvement, ensuring design parameter targets are met. The results from this new proposed design yields ∼2300× decrease in the rate of CMP wear due to NBTI compared to that of ∼28× decrease shown by previous work.
Molecular docking studies of myxobacterial disorazoles and tubulysins to tubulin

Objective: Vinca alkaloids and taxanes are tubuline inhibitors in cancer therapy, whose value is restricted by drug resistance and severe side effects. Novel classes of microtubule-stabilizing agents have been developed, including the myxobacterial epothilones, disorazoles and tubulysins. Methods: The binding of two disorazoles (A1, C3) and five tubulysins (pretubulysin, desmethyltubulysin, tubulysins A, B and D) to tubulin was investigated an in silico molecular docking approach. The results were compared with six epothilones (A-F) as well as vinblastine and paclitaxel as control drugs. Results: Epothilones, disorazoles and tubulysins bound to both the vinblastine and paclitaxel binding sites of tubulin. Tubulysins and disorazoles bound with weaker affinity to tubulins as epothilones did. Epothilones showed binding energies close to that of vinblastine at the vinblastine pharmacophore. Conclusions: These results imply that the paclitaxel binding site, which was thought to be exclusive for microtubule-stabilizing drugs may also bind microtubule-destabilizing agents. This may be explained by the fact that the binding site of paclitaxel extends over regions that are relatively close to those of vinblastine.