Miracle-dz/UniFAR-FTUs huggingface dataset:
Education-Based Family Empowerment in Diabetic Foot Ulcer Early Detection Using Ipswich Touch Test of Knowledge and Skills

Identifying patients with diabetes mellitus who experience an impaired sensation that ultimately causes Diabetic Foot Ulcer (DFU) is a necessary action. One of the efforts to prevent diabetic foot is to identify, which can be done by family members of the patient at home, but this has not been done. The aim is to determine the effect of education-based family empowerment in the early detection of Diabetic Foot Ulcers using the Ipswich Touch Test on knowledge and skills at the Mataram City Health Center. The design used a pre-experimental design with a pre-post one-group test. The sample was 45 respondents given family empowerment interventions through coaching in educational programs four times a week for two weeks. The results of family knowledge before being given the intervention were mostly lacking, as many as 36 people (86.7%), while after being given the intervention, all respondents got good knowledge, as many as 45 people (100% and p-value = 0.000 < = 0.005 coaching with p = 0.000 and skills All of the skill families before being given the intervention had poor skills as many as 45 people (100%) and after being given the intervention all respondents got good skills as many as 45 people (100%) p = 0.000 < = 0.005. So it can be concluded that education-based family empowerment in early detection of diabetic foot ulcers using the Ipswich touch test on knowledge and skills.
Novel Immunotherapeutic Approaches to Treating HPV-Related Head and Neck Cancer

Simple Summary Recent advances in immunotherapeutic approaches have spanned different tumor types including head and neck cancer. HPV-related head and Neck Cancers are virally driven tumors with notable immune characteristics and recent advances in immune targeting that desrve a closer examination. We aimed in this comprehensive review to offer a description of recent advances in immunotherapeutic applications in this disease. Abstract Head and neck cancer (HNC) is the seventh most common malignancy, with oropharyngeal squamous cell carcinoma (OPSCC) accounting for a majority of cases in the western world. While HNC accounts for only 5% of all cancers in the United States, the incidence of a subset of OPSCC caused by human papillomavirus (HPV) is increasing rapidly. The treatment for OPSCC is multifaceted, with a recently emerging focus on immunotherapeutic approaches. With the increased incidence of HPV-related OPSCC and the approval of immunotherapy in the management of recurrent and metastatic HNC, there has been rising interest in exploring the role of immunotherapy in the treatment of HPV-related OPSCC specifically. The immune microenvironment in HPV-related disease is distinct from that in HPV-negative OPSCC, which has prompted further research into various immunotherapeutics. This review focuses on HPV-related OPSCC, its immune characteristics, and current challenges and future opportunities for immunotherapeutic applications in this virus-driven cancer.
DIRECT MEASUREMENT OF GAP STATE ABSORPTION IN HYDROGENATED AMORPHOUS SILICON BY PHOTOTHERMAL DEFLECTION SPECTROSCOPY

We have measured the subgap otpical absorption of undoped, singly doped, and compensated hydrogenated amorphous silicon down to 0.6 eV using the sensitive technique of photothermal deflection spectroscopy. We show that this absorption is due to silicon dangling-bond defects located approx.1. 4 eV below the conduction band. While doping also creates defects approx.1. 4 eV below the conduction band, compensation removes them. The results suggest that for the undoped material the density-of-states maximum found in field-effect measurements is due to silicon dangling bonds.
Comparison on Prediction Abilities of Single-Input Neuronets Activated by Different Polynomials

Based on the theory of function approximation and polynomial interpolation, polynomial neuronets are constructed by using linearly independent or orthogonal polynomials as activation functions of hidden-layer neurons. After using Legendre polynomials, Hermite polynomials, Chebyshev polynomials of class I, Chebyshev polynomials of class II, Bernoulli polynomials and power functions as activation functions to construct single-input neuronets, a weights-and-structure-determination algorithm of growing type is proposed, which can be applied to these six aforementioned neuronets to determine the optimal structure and weights. With this algorithm, the abilities of learning and prediction of these six neuronets activated by different polynomials are further investigated. Simulation results show that, though the Hermite polynomial neuronet and the Bernoulli polynomial neuronet perform relatively ordinarily, other four neuronets possess superior abilities of learning and prediction. Finally, the neuronet using Chebyshev polynomials of class I is used to simulate the trend of the world population.
UNESCO world heritage sites and sustainable local community development

ABSTRACT While the literature connects the development of World Heritage Sites (WHS) and their host communities, issues of mutual developmental relevance to the sites and the communities are hardly explored for collaborative development actions. This study explored issues of common developmental relevance to selected WHS in coastal Ghana and their host communities. Data were collected from local-level stakeholders – heritage site managers, community residents, and municipal authorities. Common issues of developmental relevance that needed to be addressed related to poor sanitation, harassment of tourists, demarcation of the heritage-protected areas, and beach sand mining. Since the development of WHS and their host communities is linked, the stakeholders are urged to collaboratively develop and implement management plans that take into account the development imperatives of the two entities. Such action-oriented, mutually beneficial plans need to be informed by research and driven by a stakeholder-participatory framework to ensure inclusion and ownership for sustainable development.
Advanced Eddy-Viscosity and Reynolds-Stress Turbulence Model Simulations of Aerospace Applications

DOI: 10.2514/1.29332 Recent improvements on a three-dimensional unstructured-mesh finite-volume method, which solves the Reynolds-averaged Navier–Stokes equations for complex aerospace applications, are presented. The correct modeling of turbulence effects in aerospace flows is paramount for their successful computation. Linear one- and two-equation models are considered. The linear approximation is also extended to include a nonlinear formulation resulting from an explicit algebraic Reynolds-stress model. Two Reynolds-stress closures are also available. Nonlineareddy-viscosity andReynolds-stressmodelsnaturallyoffer thepotentialformore reliablepredictionsthan linear approximations because anisotropy of the Reynolds stresses can be accounted for. Experimental and direct numerical simulation results are usedfor verificationand validation ofthe turbulence modelimplementation. Focus is directed toward the effect of anisotropy for the resolution of the interaction between shock waves and boundary layers. In general, good agreement with theoretical or experimental results is obtained.
The Acute and Chronic Effects of Resistance and Aerobic Exercise in Hemostatic Balance: A Brief Review

Hemostatic balance refers to the dynamic balance between blood clot formation (coagulation), blood clot dissolution (fibrinolysis), anticoagulation, and innate immunity. Although regular habitual exercise may lower the incidence of cardiovascular diseases (CVD) by improving an individual’s hemostatic profile at rest and during exertion, vigorous exercise may increase the risk of sudden cardiac death and venous thromboembolism (VTE). This literature review aims to investigate the hemostatic system’s acute and chronic adaptive responses to different types of exercise in healthy and patient populations. Compared to athletes, sedentary healthy individuals demonstrate similar post-exercise responses in platelet function and coagulatory and fibrinolytic potential. However, hemostatic adaptations of patients with chronic diseases in regular training is a promising field. Despite the increased risk of thrombotic events during an acute bout of vigorous exercise, regular exposure to high-intensity exercise might desensitize exercise-induced platelet aggregation, moderate coagulatory parameters, and up-regulate fibrinolytic potential via increasing tissue plasminogen activator (tPA) and decreasing plasminogen activator inhibitor (PAI-1) response. Future research might focus on combining different types of exercise, manipulating each training characteristic (frequency, intensity, time, and volume), or investigating the minimal exercise dosage required to maintain hemostatic balance, especially in patients with various health conditions.
Prevention of Fungal Contamination in Semi-Hard Cheeses by Whey–Gelatin Film Incorporated with Levilactobacillus brevis SJC120

Cheese whey fermented by lactic acid bacteria (LAB) was used to develop an edible film with antifungal properties. Five LAB strains isolated from artisanal cheeses were screened for antifungal activity and incorporated into a whey–gelatin film. Of the strains tested, Levilactobacillus brevis SJC120 showed the strongest activity against five filamentous fungi isolated from cheese and cheese-making environment, at both 10 °C and 20 °C. The cell-free supernatant from L. brevis inhibited fungal growth by more than 80%. Incorporation of bacterial cells into the film did not alter the moisture content, water vapor permeability, or mechanical and optical properties. The whey–gelatin film was also able to maintain the viability of L. brevis cells at 107 log CFU/g after 30 days at 10 °C. In cheeses wrapped with L. brevis film, the size of fungal colonies decreased by 55% to 76%. Furthermore, no significant differences (p > 0.05) were observed in cheese proteolysis or in the moisture, fat, and protein content of the cheese wrapped with films. The results showed that whey–gelatin film with L. brevis SJC120 can reduce the contamination of cheese with filamentous fungi and could be used as an alternative to conventional cheese preservation and packaging.
Laminated barrel axial stiffness assessment [of railguns]

Metallic laminations have proven an effective and robust means of containing the electromagnetic bursting loads imposed on railgun rails. The axial stiffness of this containment type, however, has not received adequate development focus. In weapon applications, the axial stiffness is extremely important for improving gun accuracy, by limiting barrel droop and by withstanding high slew rates during aiming. One issue is to what extent the laminations ran be used to provide "bending moment inertia" to resist the slewing and gravity loads on the barrel. A simple experiment was devised to determine the static and dynamic equivalent stiffness of such structures. The authors assessed the feasibility of achieving adequate barrel stiffness using laminated barrel structure with axial stiffeners, and developed and validated a mathematical model of the axial stiffness of laminated barrels. This paper describes this model along with the experimentation and the accompanying experimental results.
CdSSe Nano-Flowers for Ultrasensitive Raman Detection of Antibiotics

Surface-enhanced Raman scattering (SERS) technique is widely used for the highly sensitive detection of trace residues due to its unparalleled signal amplification ability and plays an important role in food safety, environmental monitoring, etc. Herein, CdSSe nano-flowers (CdSSe NFs) are synthesized via the chemical vapor deposition (CVD) method. CdSSe NFs thin film is used as a SERS substrate with an ultralow limit of detection (LOD, 10−14 M), high apparent enhancement factor (EF, 3.62 × 109), and excellent SERS stability (relative standard deviation, RSD = 3.05%) for probe molecules of Rh6G. Further, CdSSe NFs substrate is successfully applied in the sensitive, quantitative, and label-free analysis of ciprofloxacin (CIP) and enrofloxacin (ENR) antibiotics, which exhibit LODs of below 0.5 ppb. This excellent SERS platform may be widely utilized for sensitive life science and environmental sensing.
Intrinsic radiation tolerance of ultra-thin GaAs solar cells

Radiation tolerance is a critical performance criterion of photovoltaic devices for space power applications. In this paper we demonstrate the intrinsic radiation tolerance of an ultra-thin solar cell geometry. Device characteristics of GaAs solar cells with absorber layer thicknesses 80 nm and 800 nm were compared before and after 3 MeV proton irradiation. Both cells showed a similar degradation in Voc with increasing fluence; however, the 80 nm cell showed no degradation in Isc for fluences up to 1014 p+ cm−2. For the same exposure, the Isc of the 800 nm cell had severely degraded leaving a remaining factor of 0.26.
Diminishing the Pathogenesis of the Food-Borne Pathogen Serratia marcescens by Low Doses of Sodium Citrate

Simple Summary Sodium citrate is a safe and frequently used food additive; the objective of this study is to assess the effectiveness of sodium citrate at low concentrations of 4% or 5% in combating Serratia marcescens, a food bacterial contaminant, by evaluating its anti-biofilm and anti-virulence properties. The current finding showed the significant ability of sodium citrate to inhibit the formation and virulence of bacterial biofilm. Furthermore, sodium citrate mitigated the bacterial pathogenesis on the infected mice. This study paves the way to use sodium citrate in low doses to reduce the harmful effects of S. marcescens and other bacteria that can cause foodborne illnesses. The use of sodium citrate could be an effective method to prevent the spread of this contaminating bacteria and improve food safety. Abstract Protecting food from bacterial contamination is crucial for ensuring its safety and avoiding foodborne illness. Serratia marcescens is one of the food bacterial contaminants that can form biofilms and pigments that spoil the food product and could cause infections and illness to the consumer. Food preservation is essential to diminish such bacterial contaminants or at least reduce their pathogenesis; however, it should not affect food odor, taste, and consistency and must be safe. Sodium citrate is a well-known safe food additive and the current study aims to evaluate its anti-virulence and anti-biofilm activity at low concentrations against S. marcescens. The anti-virulence and antibiofilm activities of sodium citrate were evaluated phenotypically and genotypically. The results showed the significant effect of sodium citrate on decreasing the biofilm formation and other virulence factors, such as motility and the production of prodigiosin, protease, and hemolysins. This could be owed to its downregulating effect on the virulence-encoding genes. An in vivo investigation was conducted on mice and the histopathological examination of isolated tissues from the liver and kidney of mice confirmed the anti-virulence activity of sodium citrate. In addition, an in silico docking study was conducted to evaluate the sodium citrate binding ability to S. marcescens quorum sensing (QS) receptors that regulates its virulence. Sodium citrate showed a marked virtual ability to compete on QS proteins, which could explain sodium citrate’s anti-virulence effect. In conclusion, sodium citrate is a safe food additive and can be used at low concentrations to prevent contamination and biofilm formation by S. marcescens and other bacteria.
Mathematical analysis of a PML model obtained with stretched coordinates and its application to backward wave propagation in metamaterials

We investigate the well‐posedness of a perfectly matched layer model developed by Cohen and Monk [Comput Methods Appl Mech Eng 169 (1999), 197–217]. A new time‐domain finite element method is proposed to solve the model. A novel feature of the scheme is that the number of unknowns is reduced to two from four in the original form. The scheme's effectiveness is demonstrated through numerical experiments. © 2013 Wiley Periodicals, Inc. Numer Methods Partial Differential Eq 30: 1558–1574, 2014
A comparison of radio data and model calculations of Jupiter's synchrotron radiation 2. East-west asymmetry in the radiation belts as a function of Jovian longitude

On the basis of a comparison of radio data and model calculations of Jupiter's synchrotron radiation the ‘hot region’ or east-west asymmetry in the planet's radiation belts is proposed to be due to the combined effect of an overabundance of electrons at jovicentric longitudes λJ ∼240°–360° and the existence of a dusk to dawn directed electric field over the inner magnetosphere, generated by the wind system in the upper atmosphere. The model calculations were based upon the magnetic field configurations derived from the Pioneer data by Acuna and Ness [1976] (the O4 model) and Davis, Jones and Smith (quoted in Smith and Gulkis [1979]) (the P11 (3,2)A model), with an electron distribution derived in the first paper of this series [de Pater, this issue]. We would infer from the calculations that the O4 model gives a slightly better fit to the data; the relatively large number density at λJ ∼240°–360°, however, might indicate the presence of even higher order moments in the field.
Acceptance of Zakat E-payment System: A Perception of Undergraduates

Zakat E-payment is one of the product innovations that is a widely spread method to facilitate the contribution of zakat in the present world. Online payment is an important method of transaction widely practiced across the globe. Due to its flexibility and convenience, it has been a popular payment method recently, especially in critical religious matters such as zakat, one of the pillars of Islam. The main objective of the study is to analyse the acceptance of the zakat e-payment system from the perception of undergraduates as they are potential payors in the future as they enter the workforce. Specifically, factors influencing the acceptance of zakat e-payment will be determined. The study’s conceptual framework is based on the Theory of Acceptance (TAM), where six variables or constructs, namely financial literacy (FL), perceived usefulness (PU), Perceived Ease of Use (PEU), Enjoyment (ENJ), Attitude (ATT) and Behavioural Intention (BI). This cross-section study employs a data set comprising 210 undergraduate students. Data was collected using a close-ended questionnaire. The results, among others, recommend that zakat e-payment system providers modify or create highly usable applications. Therefore, marketing initiatives should focus on promoting these zakat e-payment system characteristics.
Genetic diversity estimates in landraces of pumpkin (Cucurbita moschata) from North Eastern Himalayan region of India using agro-morphological and molecular traits

The present investigation was carried out to assess the diversity existing among the landraces of pumpkin (Cucurbita moschata Duch.) from North Eastern Himalayan region of India. Clustering analysis based on morphological and molecular traits exhibited high level of genetic diversity and grouped the pumpkin landraces into 5 major clusters. Maximum and minimum inter-cluster average D2 values obtained were 442.27 and 86.29, respectively. High degree of correlation was found between diversity obtained by morphological and molecular traits. The highest and lowest PIC values of SSR markers observed was 0.91 (OCM2) and 0.30 (OCM9) respectively and the Jaccard's similarity coefficient ranged from 0.51 to 0.92. The most divergent landraces obtained (GHP 1, GHP 26, GHP 43, GHP 51, GHP 52 GHP 56) from this study can be effectively utilized in future pumpkin breeding programme for development of new hybrid combinations.
The Magnetic Field Strength in the Wall of the Local Bubble toward l, b ≈ 300°, 0°

We present polarization measurements in the region around l, b = 300°, 0°, toward stars with well-determined distances, primarily in the range 40-200 pc. We argue that these observations trace polarization caused by dust in the wall of the Local Bubble (LB). Using a Chandrasekhar-Fermi analysis, we derive a plane-of-the-sky magnetic field strength, in the wall of the LB in this direction, of = 8 μG, equivalent to a magnetic pressure of PB/k ≈ 1.8 × 104 K cm-3. This pressure equals, to within the uncertainties, that in the bubble interior, as derived from EUVE observations, assuming collisional ionization equilibrium. Such a magnetic field could help us explain the observed low O VI column density associated with the LB wall.
Probing the luminous stellar cores of the giant H II regions 30 DOR in the LMC and NGC 3603 in the Galaxy

The present discussion of the stellar content of the two prototype supergiant H II regions, 30 Doradus and NGC 3603, is conducted on the basis of new narrow and wide band CCD images of their central 3 X 5 arcmin, together with moderate resolution IDS spectroscopy of the central luminous object HD 38268 and other resolved W-R stars in 30 Dor, and of the central luminous object HD 97950 in NGC 3603. It is noted that a CCD, in combination with narrow (35-A wide) filters at 4650 A (C IV) and 4686 A (He II), is very effective in revealing all W-R stars in a broad and complex region. The overall radial surface brightness distribution in the 350-A filter at 4700 A satisfies the semiempirical King profile for spherically symmetric, isothermal stellar systems, over a span of two magnitudes in radius. 59 references.
Examining the Prevalence and Antibiotic Susceptibility of S. aureus Strains in Hospitals: An Analysis of the pvl Gene and Its Co-Occurrence with Other Virulence Factors

S. aureus is a pathogenic bacterium that causesinfections. Its virulence is due to surface components, proteins, virulence genes, SCCmec, pvl, agr, and SEs, which are low molecular weight superantigens. SEs are usually encoded by mobile genetic elements, and horizontal gene transfer accounts for their widespread presence in S. aureus. This study analyzed the prevalence of MRSA and MSSA strains of S. aureus in two hospitals in Greece between 2020–2022 and their susceptibility to antibiotics. Specimens collected were tested using the VITEK 2 system and the PCR technique to detect SCCmec types, agr types, pvl genes, and sem and seg genes. Antibiotics from various classes were also tested. This study examined the prevalence and resistance of S. aureus strains in hospitals. It found a high prevalence of MRSA and that the MRSA strains were more resistant to antibiotics. The study also identified the genotypes of the S. aureus isolates and the associated antibiotic resistances. This highlights the need for continued surveillance and effective strategies to combat the spread of MRSA in hospitals. This study examined the prevalence of the pvl gene and its co-occurrence with other genes in S. aureus strains, as well as their antibiotic susceptibility. The results showed that 19.15% of the isolates were pvl-positive and 80.85% were pvl-negative. The pvl gene co-existed with other genes, such as the agr and enterotoxin genes. The results could inform treatment strategies for S. aureus infections.
Electrified coating flows on vertical fibres: enhancement or suppression of interfacial dynamics

Abstract We investigate the evolution and stability of a wetting viscous fluid layer flowing down the surface of a cylinder, and surrounded by a conductive gas. The inner cylinder is an electrode kept at constant voltage, and a second, concentric electrode encloses the system whose potential is allowed to vary spatially. This induces electrostatic forces at the interface in competition with surface tension and viscous stresses. Asymptotic methods are used to derive a long-wave axisymmetric model governing the interfacial position and charge density. The resulting system of equations is investigated both analytically and numerically to determine its stability characteristics in the linear and nonlinear regimes.