Miracle-dz/UniFAR-FTUs huggingface dataset:
Determinants of chronic energy deficiency among non-pregnant and non-lactating women of reproductive age in rural Kebeles of Dera District, North West Ethiopia, 2019: Unmatched case control study

Background In Ethiopia about 25% of rural women are chronically malnourished. Non-pregnant and non-lactating women present an opportunity to implement strategies to correct maternal and child health status and to potentiate improved pregnancy outcomes in developing countries like Ethiopia. The determinant factors of chronic energy deficiency vary across settings and contexts; hence, it is important to identify local determinant factors in order to implement effective and efficient intervention strategies. Objective To assess the determinants of chronic energy deficiency of non-pregnant, non-lactating rural women within the reproductive age group (15–49 years), in rural kebeles of Dera district, North West Ethiopia, 2019. Methods A community based unmatched case control study was conducted. A total of 552 participants were involved and a multi-stage sampling technique was used to select the samples. Data was collected from January 15 to February 30, 2019 using face-to-face interviews and anthropometric assessments. EPI-info version 7 and SPSS™ version 23 were used for data entry and analysis, respectively. Bivariable and multivariable logistic regression models were used to analyze the association between dependent and independent variables. Association was considered statistically significant at 95% CI with p-value < 0.05 in multivariable logistic regression. Result A total of 548 non-pregnant, non-lactating women with 137 cases and 411 controls were included in the study with a response rate of 99.3%. High family size (AOR = 1.88, 95% CI: 1.085, 3.275), low educational status (AOR = 3.389, 95% CI: 1.075, 10.683), inadequate meal frequency (AOR = 5.345, 95% CI: 2.266, 12.608), absence of home garden (AOR = 5.612, 95% CI: 3.177, 9.915) and absence of latrine facility (AOR = 6.365, 95% CI: 3.534, 11.462) were found positively associated with chronic energy deficiency. Conclusion and recommendation Inadequate meal frequency, absence of home gardening, absence of latrine facility, high family size and educational status of illiterate were the determinants of chronic energy deficiency, thus indicating the imperative for a multi-sectoral approach with health, agriculture and education entities developing and delivering interventions.
Effectiveness of a Novel Dentifrice Containing Stabilized Chlorine Dioxide, Sarkosyl, and Sodium Fluoride

This in vitro study evaluated the effectiveness of a novel dentifrice containing stabilized chlorine dioxide, sodium lauroyl sarcosinate (sarkosyl), and sodium fluoride in enhancing enamel fluoride uptake, remineralization, pellicle cleaning and inhibiting biofilm regrowth. Remineralization was measured by fluoride uptake and surface microhardness assessment tests. Artificial stains were removed and scored based on pellicle cleaning ratio. Biofilm regrowth was measured by counting colonies on the agar plates. All studies were conducted using bovine teeth specimens. The efficacy of Toothpaste C (CloSYS anticavity toothpaste) was compared with United States Pharmacopoeia Reference Dentifrice, Toothpaste B (discontinued CloSYS anticavity toothpaste formulation) and leading commercial toothpastes. The enamel fluoride uptake and remineralization by Toothpaste C was 96.1% to 303.3% and 38.0% to 102.4% higher than the tested toothpastes, respectively. The mean pellicle cleaning ratio of Toothpaste C was similar to American Dental Association Reference Material. Toothpaste C had a significant reduction in regrowth of the oral polymicrobial biofilm compared to the control. All tested toothpastes contained 0.24% sodium fluoride. Toothpaste C exhibited significantly superior performance towards fluoride uptake and remineralization compared to the tested toothpastes. Therefore, toothpaste ingredients other than sodium fluoride accounted for the enhanced fluoride uptake and remineralization.
No Laughing Matter: How Humor Styles Relate to Feelings of Loneliness and Not Mattering

Loneliness and feeling that one does not matter are closely linked, but further investigation is needed to determine differentiating features. The relationship between not mattering to others (anti-mattering) and loneliness was explored by assessing how the two constructs correlated with an interpersonal dimension, specifically four humor styles (affiliative, self-enhancing, self-defeating, and aggressive). One hundred and fifty-eight women and 96 men completed a three-item loneliness scale, a new measure of anti-mattering, and a humor styles questionnaire. Confirmatory factor analysis results indicated that the new anti-mattering measure is a unidimensional scale. Loneliness and anti-mattering were strongly correlated, and each correlated in the same direction with approximately the same magnitude as the four humor styles. The discussion concludes that anti-mattering and loneliness are strongly linked, a finding which may be important in psychological treatment. Humor styles also play a role in psychological well-being and present a unique pathway to mental health.
Risk perception and precautionary health behavior toward COVID-19 among health professionals working in selected public university hospitals in Ethiopia

Objective This study was designed to determine risk perception and precautionary health behavior toward coronavirus disease (COVID-19) among health professionals working in selected public university hospitals of Ethiopia. Methods A web-based cross-sectional survey was used with health professionals working in selected public university hospitals of Ethiopia. A structured survey questionnaire consisted of socio-demographic, risk perception, and behavioral response items were used. The survey questions were designed on Google form. All academic and clinical staff invited to participate in the online survey, which was carried out from May 1–14, 2020. Data analysis was done using the Statistical Package for Social Sciences version 24. Descriptive statistics computed and the result is presented by tables and figures. Results A total of 273 health professionals participated in this study. The mean (± SD) age of participants was 31.03 ± 5.11. Study participants’ overall mean score of perceived risk was 23.59 ± 4.75. The study participants’ mean score of perceived vulnerability (4.01 ± 1.17) was higher than the human immunodeficiency virus, common cold, malaria, and tuberculosis. Regarding precautionary health behavior, the lowest mean score is for wearing gloves 1.82 ± 1.15. Conclusion Participants mean score of perceived vulnerability of coronavirus disease was higher than some of the prevalent infectious disease in the area. Almost all participants applied recommended protective measures to the acceptable level, except for wearing mask and gloves. Therefore, there is a need to further intensification of more effective ways to support health professionals’ adherence to major precautionary measure is important.
Automatic Guidance (and Misguidance) of Visuospatial Attention by Acquired Scene Memory: Evidence From an N1pc Polarity Reversal

Visual search is facilitated when the target is repeatedly encountered at a fixed position within an invariant (vs. randomly variable) distractor layout—that is, when the layout is learned and guides attention to the target, a phenomenon known as contextual cuing. Subsequently changing the target location within a learned layout abolishes contextual cuing, which is difficult to relearn. Here, we used lateralized event-related electroencephalogram (EEG) potentials to explore memory-based attentional guidance (N = 16). The results revealed reliable contextual cuing during initial learning and an associated EEG-amplitude increase for repeated layouts in attention-related components, starting with an early posterior negativity (N1pc, 80–180 ms). When the target was relocated to the opposite hemifield following learning, contextual cuing was effectively abolished, and the N1pc was reversed in polarity (indicative of persistent misguidance of attention to the original target location). Thus, once learned, repeated layouts trigger attentional-priority signals from memory that proactively interfere with contextual relearning after target relocation.
Advanced Studies on Virulence Genes of Salmonella and Shigella species Isolated from Milk and Dairy Products

Salmonella and Shigella species are the main health problem in various portions of the world. This study gave rise to detect and enumerate Salmonella and Shigella species with detection of virulence genes by PCR in randomly collected raw milk and dairy products (ice cream, cheese, yoghurt, rice with milk and cream) from different vendors of village and dairy farms in Mansoura Governorate, Egypt during October 2016. A total of 24 (9.6 %) isolates from 250 samples (raw milk and dairy products) were recognised as Salmonella 6.4 % (16/250) and Shigella 3.2 % (8/250) species with their high prevalence in raw milk. Amongst serotypes of Salmonella species: S. Typhimurium 37.5 % (6/16), S. Enteritidis, S. Tsevie 18.75 % (3/16 each) and other serovars 25 % (4/16). Additionally, the identified Shigella species (8/250) were S. dysenteriae 50 % (4/8), S. flexneri 25 % (2/8) and S. sonnei 25 % (2/8). The average of total viable count of samples positive for Salmonella and Shigella in raw milk and dairy products was 4.47±0.97 log 10 CFU/ml or gm and 4.27±1.01 log 10 CFU/ml or Original Research Article Younis et al.; ARRB, 29(3): 1-11, 2018; Article no.ARRB. 44651 2 gm, respectively. Furthermore, polymerase chain reaction assay was applied for demonstration of the most common virulence associated genes of Salmonella species (invA) and Shigella species (invC, ipaH, virA). The invA gene was present in all tested Salmonella isolates. The invC and ipaH genes were present in all Shigella isolates, while virA gene was absent in all strains. This study recommended that appropriate hygienic measures, as well as continuous monitoring of Salmonella and Shigella infection, could help to control and prevent the emergence and spread of salmonellosis and shigellosis from milk and dairy products in Egypt.
Deep Neural Network for Visual Stimulus-Based Reaction Time Estimation Using the Periodogram of Single-Trial EEG

Multiplexed deep neural networks (DNN) have engendered high-performance predictive models gaining popularity for decoding brain waves, extensively collected in the form of electroencephalogram (EEG) signals. In this paper, to the best of our knowledge, we introduce a first-ever DNN-based generalized approach to estimate reaction time (RT) using the periodogram representation of single-trial EEG in a visual stimulus-response experiment with 48 participants. We have designed a Fully Connected Neural Network (FCNN) and a Convolutional Neural Network (CNN) to predict and classify RTs for each trial. Though deep neural networks are widely known for classification applications, cascading FCNN/CNN with the Random Forest model, we designed a robust regression-based estimator to predict RT. With the FCNN model, the accuracies obtained for binary and 3-class classification were 93% and 76%, respectively, which further improved with the use of CNN (94% and 78%, respectively). The regression-based approach predicted RTs with correlation coefficients (CC) of 0.78 and 0.80 for FCNN and CNN, respectively. Investigating further, we found that the left central as well as parietal and occipital lobes were crucial for predicting RT, with significant activities in the theta and alpha frequency bands.
Alteration, Reduction and Taste Loss: Main Causes and Potential Implications on Dietary Habits

Our sense of taste arises from the sensory information generated after compounds in the oral cavity and oropharynx activate taste receptor cells situated on taste buds. This produces the perception of sweet, bitter, salty, sour, or umami stimuli, depending on the chemical nature of the tastant. Taste impairments (dysgeusia) are alterations of this normal gustatory functioning that may result in complete taste losses (ageusia), partial reductions (hypogeusia), or over-acuteness of the sense of taste (hypergeusia). Taste impairments are not life-threatening conditions, but they can cause sufficient discomfort and lead to appetite loss and changes in eating habits, with possible effects on health. Determinants of such alterations are multiple and consist of both genetic and environmental factors, including aging, exposure to chemicals, drugs, trauma, high alcohol consumption, cigarette smoking, poor oral health, malnutrition, and viral upper respiratory infections including influenza. Disturbances or loss of smell, taste, and chemesthesis have also emerged as predominant neurological symptoms of infection by the recent Coronavirus disease 2019 (COVID-19), caused by Severe Acute Respiratory Syndrome Coronavirus strain 2 (SARS-CoV-2), as well as by previous both endemic and pandemic coronaviruses such as Middle East Respiratory Syndrome Coronavirus (MERS-CoV) and SARS-CoV. This review is focused on the main causes of alteration, reduction, and loss of taste and their potential repercussion on dietary habits and health, with a special focus on the recently developed hypotheses regarding the mechanisms through which SARS-CoV-2 might alter taste perception.
The association of subjective fit perceptions, distress, emotional exhaustion, and work engagement, with work functioning problems: A cross‐sectional study conducted among young construction project management professionals

Abstract Objectives To investigate the association of subjective fit perceptions, distress, emotional exhaustion, and work engagement, with work functioning, among young construction project management professionals (CPMPs). Methods The research had a cross‐sectional design. Dutch young CPMPs (142 participants, age range: 20 to 30 years of age) completed a questionnaire containing general questions recording their demographic characteristics, and instruments recording the following concepts: perceived person‐organization fit, perceived person‐job fit (including demands‐abilities fit and needs‐supplies fit), distress, emotional exhaustion, work engagement, and work functioning. Correlation analysis and multiple regression analysis were used to examine the association of fit perceptions, distress, emotional exhaustion, and work engagement, with work functioning. Results The correlation analysis indicated that person‐organization fit, needs‐supplies fit, distress, emotional exhaustion, and work engagement correlated significantly with work functioning problems of young CPMPs. The multiple regression analyses corroborated that needs‐supplies fit, distress, and emotional exhaustion related significantly to the work functioning problems of young CPMPs, with the standardized regression coefficients (β) of −0.28, 0.52, and 0.38 (P < .01), respectively. Other than would be expected, the multiple regression analyses also made clear that work engagement does not significantly relate to work functioning problems beyond distress and emotional exhaustion. Conclusions Incongruence between personal needs and job supplies, psychological distress, and emotional exhaustion are central correlates of the work functioning problems of young CPMPs. Occupational health professionals can use these insights to help young CPMPs at work.
Low-Molecular-Weight Heparin Combined With Insulin Versus Insulin Alone in the Treatment of Hypertriglyceridemic Pancreatitis (LIHTGP Trial): Study Protocol for a Multicenter, Prospective, Single-Blind, Randomized Controlled Trial.

OBJECTIVE Currently, insulin and/or heparin/low-molecular-weight heparin (LMWH) serve as an early lipid-lowering treatment for hypertriglyceridemic pancreatitis (HTGP). However, whether the clinical prognosis of combining LMWH with insulin is superior to using insulin alone remains unknown. This trial will compare the clinical outcomes of LMWH with insulin and an insulin regimen for emergency lipid-lowering treatment in HTGP patients. METHODS In total, 476 eligible participants will be recruited from 18 hospitals throughout China. Participants in the LMWH group will receive LMWH combined with insulin, whereas insulin alone will be administered to those in the insulin group. The patients will be followed up at 3 and 6 months after discharge. Adverse reactions will be evaluated by the safety monitoring committee. Safety outcomes and adverse events will also be recorded. RESULTS The study is registered in the Chinese Clinical Trial Registry (No: ChiCTR1900023640). Recruitment will begin in August 2019 and will be completed in December 2021 (http://www.chictr.org.cn/index.aspx). No data are available now. CONCLUSIONS The trial will investigate the efficacy of using LMWH combined with insulin as an emergency lipid-lowering treatment in reducing new organ failure, mortality, hospital stays, and expenses compared using with insulin alone for patients with HTGP.
The 10-Year Study of the Impact of Particulate Matters on Mortality in Two Transit Cities in North-Eastern Poland (PL-PARTICLES)

The detrimental influence of air pollution on mortality has been established in a series of studies. The majority of them were conducted in large, highly polluted cities—there is a lack of studies from small, relatively clean regions. The aim was to analyze the short-term impact of particulate matters (PMs) on mortality in north-eastern Poland. Time-stratified case-crossover design was performed for mortality in years 2008–2017. Daily concentrations of PM2.5 (28.4 µg/m3, interquartile range (IQR) = 25.2) vs. (12.6 µg/m3, IQR = 9.0) and PM10 (29.0 µg/m3, IQR = 18.0) vs. (21.7 µg/m3, IQR = 14.5) were higher in Łomża than Suwałki (p < 0.001). Impact of PM2.5 on mortality was recorded in Łomża (odds ratio (OR) for IQR increase 1.061, 1.017–1.105, p = 0.06, lag 0) and Suwałki (OR for IQR increase 1.044, 1.001–1.089, p = 0.004, lag 0). PM10 had an impact on mortality in Łomża (OR for IQR increase 1.028, 1.000–1.058, p = 0.049, lag 1). Cardiovascular mortality was affected by increase of PM2.5 in Łomża (1.086, 1.020–1.156, p = 0.01) and Suwałki (1.085, 1.005–1.171, p = 0.04). PM2.5 had an influence on respiratory mortality in Łomża (1.163, 1.021–1.380, p = 0.03, lag 1). In the whole studied region, despite differences in the air quality, the influence of PMs on mortality was observed.
A physiology‐based Earth observation model indicates stagnation in the global gross primary production during recent decades

Earth observation‐based estimates of global gross primary production (GPP) are essential for understanding the response of the terrestrial biosphere to climatic change and other anthropogenic forcing. In this study, we attempt an ecosystem‐level physiological approach of estimating GPP using an asymptotic light response function (LRF) between GPP and incoming photosynthetically active radiation (PAR) that better represents the response observed at high spatiotemporal resolutions than the conventional light use efficiency approach. Modelled GPP is thereafter constrained with meteorological and hydrological variables. The variability in field‐observed GPP, net primary productivity and solar‐induced fluorescence was better or equally well captured by our LRF‐based GPP when compared with six state‐of‐the‐art Earth observation‐based GPP products. Over the period 1982–2015, the LRF‐based average annual global terrestrial GPP budget was 121.8 ± 3.5 Pg C, with a detrended inter‐annual variability of 0.74 ± 0.13 Pg C. The strongest inter‐annual variability was observed in semi‐arid regions, but croplands in China and India also showed strong inter‐annual variations. The trend in global terrestrial GPP during 1982–2015 was 0.27 ± 0.02 Pg C year−1, and was generally larger in the northern than the southern hemisphere. Most positive GPP trends were seen in areas with croplands whereas negative trends were observed for large non‐cropped parts of the tropics. Trends were strong during the eighties and nineties but levelled off around year 2000. Other GPP products either showed no trends or continuous increase throughout the study period. This study benchmarks a first global Earth observation‐based model using an asymptotic light response function, improving simulations of GPP, and reveals a stagnation in the global GPP after the year 2000.
Virtual care expansion in the Veterans Health Administration during the COVID-19 pandemic: clinical services and patient characteristics associated with utilization

Abstract Objectives To describe the shift from in-person to virtual care within Veterans Affairs (VA) during the early phase of the COVID-19 pandemic and to identify at-risk patient populations who require greater resources to overcome access barriers to virtual care. Materials and Methods Outpatient encounters (N = 42 916 349) were categorized by care type (eg, primary, mental health, etc) and delivery method (eg, in-person, video). For 5 400 878 Veterans, we used generalized linear models to identify patient sociodemographic and clinical characteristics associated with: 1) use of virtual (phone or video) care versus no virtual care and 2) use of video care versus no video care between March 11, 2020 and June 6, 2020. Results By June, 58% of VA care was provided virtually compared to only 14% prior. Patients with lower income, higher disability, and more chronic conditions were more likely to receive virtual care during the pandemic. Yet, Veterans aged 45–64 and 65+ were less likely to use video care compared to those aged 18–44 (aRR 0.80 [95% confidence interval (CI) 0.79, 0.82] and 0.50 [95% CI 0.48, 0.52], respectively). Rural and homeless Veterans were 12% and 11% less likely to use video care compared to urban (0.88 [95% CI 0.86, 0.90]) and nonhomeless Veterans (0.89 [95% CI 0.86, 0.92]). Discussion Veterans with high clinical or social need had higher likelihood of virtual service use early in the COVID-19 pandemic; however, older, homeless, and rural Veterans were less likely to have video visits, raising concerns for access barriers. Conclusions and Relevance While virtual care may expand access, access barriers must be addressed to avoid exacerbating disparities.