Miracle-dz/UniFAR-FTUs huggingface dataset:
How Adolescents Cope with Technostress: A Mixed-Methods Approach

ABSTRACT A broad stream of research strives to understand stress directly or indirectly resulting from the use of information and communication technology (ICT), commonly referred to as technostress. A group at high risk of suffering from the consequences of technostress is adolescents because they grow up using ICT daily and are still developing their identity, acquiring mental strength, and adopting essential social skills. Our research combines a qualitative and a quantitative study and contributes to an understanding of what strategies adolescents use to cope with the demands of ICT use. In qualitative workshops with adolescents, we collect 30 coping responses in five categories. A subsequent quantitative study finds gender- and age-related differences in adolescents’ perception of technostress and concludes that adolescents as a group activate a broad portfolio of coping responses. Exploratory factor analysis reveals five factors underlying adolescents’ activation of coping responses: Avoid Stressful ICT, Follow the Rules, Use ICT Consciously, Contain Negative Emotions, and Acquire ICT. We find that the coping responses related to the Avoid Stressful ICT factor are significantly more common among girls than boys and derive that adolescents who own more devices might have a lower tendency to Follow the Rules. A joint analysis of coping responses and technostress creators reveals that, not surprisingly, coping increases with higher intensity of technostress, but some coping responses break out of this pattern. With this research, we contribute to the theoretical and empirical understanding of an important phenomenon associated with digitalization’s dark sides (technostress coping) in an important yet understudied population (adolescents 10–17 years of age). Future research may build on our work and investigate additional parameters determining differences in adolescents’ coping behavior.
Using intentional and incidental encoding instructions to test the transfer inappropriate processing shift account of verbal overshadowing

ABSTRACT A major assumption of the transfer inappropriate processing shift account of verbal overshadowing is that poor recognition performance is due to competing and inappropriate processes used during the encoding, recall, and recognition stages. The present study tested the TIPS account. Participants watched a video of a burglary during an encoding task and attempted to identify the burglar from a photo lineup during a recognition task. Encoding and recall instructions were varied between participants to encourage featural or configural processes at the encoding and recall stages. Prior to the encoding task, some participants were given intentional encoding instructions to focus on the face of the person in the video. Other participants were given incidental encoding instructions or not told anything. Prior to the recall task, some participants were given instructions to recall the description of the burglar, and other participants were not. Results revealed an interaction between encoding and recall instructions on recognition performance.
Tobit Kalman filter with channel fading and dead-zone-like censoring

In complex control systems, the channel fading and the measurement censoring are often unavoidable due to sudden environmental changes, intermittent transmission congestions, random failures and repairs of components. To this end, the Tobit Kalman filtering problem for discrete-time systems with the dead-zone-like censoring and channel fading is studied where the censoring and fading phenomena are, respectively, described by the Tobit measurement model and the -order Rice fading channel model. The design of the filter is carried out in two stages: (1) the state augmentation technique is firstly adopted to remove the time-delay effect caused by the fading channel; and (2) the statistical information of censored measurements is used to determine the optimal filter structure in the minimum mean-square error sense, where the orthogonal projection principle is utilised to avoid the deep correlations among the multiple random variables induced by measurement censoring and channel fading. Besides, the desired filter is also devised based on the approach of the conditional expectation. For the convenience of calculation, the filter with the dead-zone-like censoring is converted into an equivalent one with one-side censoring. Finally, a numerical example of estimating the ballistic ball rates is given to verify the effectiveness of the proposed filters.
Reviving social banking using relationship quality dynamics in a developing country

ABSTRACT Service sectors are the backbone of any economy. Due to the recent pandemic, this sector has been hit the hardest in developing countries. People are becoming unemployed, and the poverty rate is increasing at an unprecedented rate. Social banking, such as Grameen Bank, has played an essential role in lifting the poor out of poverty in various critical environments. Although relationship quality with customers plays a crucial role in this transformative banking services, there is a lack of research exploring its dimensions that made this sector sustainable. This paper aims to propose a social banking relationship quality framework by conducting a systematic literature review, 30 in-depth interviews and thematic analysis. The findings show that trust, respect and reciprocity are the primary critical relationship quality dimensions for sustaining social banking services in developing countries.
Novel Spirobifluorene- and Dibromospirobifluorene-Based Polyimides of Intrinsic Microporosity for Gas Separation Applications

Two series of novel intrinsically microporous polyimides were synthesized from 9,9′-spirobifluorene-2,2′-diamine (SBF) and its bromine-substituted analogue 3,3′-dibromo-9,9′-spirobifluorene-2,2′-diamine (BSBF) with three different dianhydrides (6FDA, PMDA, and SPDA). All polymers exhibited high molecular weight, good solubility in common organic solvents, and high thermal stability. Bromine-substituted polyimides showed significantly increased gas permeabilities but slightly lower selectivities than the SBF-based polyimides. The CO2 permeability of PMDA–BSBF (693 Barrer) was 3.5 times as high as that of PMDA–SBF (197 Barrer), while its CO2/CH4 selectivity was similar (19 vs 22). Molecular simulations of PMDA–SBF and PMDA–BSBF repeat units indicate that the twist angle between the PMDA and fluorene plane changes from 0° in PMDA–SBF to 77.8° in PMDA–BSBF, which decreases the ability of the polymer to pack efficiently due to severe steric hindrance induced by the bromine side groups.
RuSseL: A Self-Consistent Field Theory Code for Inhomogeneous Polymer Interphases

In this article, we publish the one-dimensional version of our in-house code, RuSseL, which has been developed to address polymeric interfaces through Self-Consistent Field calculations. RuSseL can be used for a wide variety of systems in planar and spherical geometries, such as free films, cavities, adsorbed polymer films, polymer-grafted surfaces, and nanoparticles in melt and vacuum phases. The code includes a wide variety of functional potentials for the description of solid–polymer interactions, allowing the user to tune the density profiles and the degree of wetting by the polymer melt. Based on the solution of the Edwards diffusion equation, the equilibrium structural properties and thermodynamics of polymer melts in contact with solid or gas surfaces can be described. We have extended the formulation of Schmid to investigate systems comprising polymer chains, which are chemically grafted on the solid surfaces. We present important details concerning the iterative scheme required to equilibrate the self-consistent field and provide a thorough description of the code. This article will serve as a technical reference for our works addressing one-dimensional polymer interphases with Self-Consistent Field theory. It has been prepared as a guide to anyone who wishes to reproduce our calculations. To this end, we discuss the current possibilities of the code, its performance, and some thoughts for future extensions.
Neuroprotective Effects of Dexmedetomidine on the Ketamine-Induced Disruption of the Proliferation and Differentiation of Developing Neural Stem Cells in the Subventricular Zone

Background: Ketamine disrupts the proliferation and differentiation of developing neural stem cells (NSCs). Therefore, the safe use of ketamine in pediatric anesthesia has been an issue of increasing concern among anesthesiologists and children's parents. Dexmedetomidine (DEX) is widely used in sedation as an antianxiety agent and for analgesia. DEX has recently been shown to provide neuroprotection against anesthetic-induced neurotoxicity in the developing brain. The aim of this in vivo study was to investigate whether DEX exerted neuroprotective effects on the proliferation and differentiation of NSCs in the subventricular zone (SVZ) following neonatal ketamine exposure. Methods: Postnatal day 7 (PND-7) male Sprague-Dawley rats were equally divided into the following five groups: control group (n = 8), ketamine group (n = 8), 1 μg/kg DEX+ketamine group (n = 8), 5 μg/kg DEX+ketamine group (n = 8) and 10 μg/kg DEX+ketamine group (n = 8). Immediately after treatment, rats received a single intraperitoneal injection of BrdU, and the proliferation and differentiation of NSCs in the SVZ were assessed using immunostaining at 24 h after the BrdU injection. In the olfactory behavioral tests, rats in each group were raised until 2 months old, and the buried food test and olfactory memory test were performed. Results: The proliferation of NSCs and astrocytic differentiation in the SVZ were significantly inhibited at 24 h after repeated ketamine exposure in the neonatal period, and neuronal differentiation was markedly increased. Furthermore, pretreatment with moderately high (5 μg/kg) or high doses (10 μg/kg) of DEX reversed ketamine-induced disturbances in the proliferation and differentiation of NSCs. In the behavior tests, repeated neonatal ketamine exposure induced olfactory cognitive dysfunction in the adult stage, and moderately high and high doses of DEX reversed the olfactory cognitive dysfunction induced by ketamine. Conclusions: Based on the present findings, pretreatment with a moderately high (5 μg/kg) or high dose (10 μg/kg) of DEX may alleviate the developmental neurogenesis disorder in the SVZ at 24 h after repeated ketamine exposure and improve olfactory cognitive dysfunction in adulthood.
Adjuvant Radiotherapy After Minimally Invasive Surgery in Patients With Stage IA1-IIA1 Cervical Cancer

To estimate whether adjuvant radiotherapy is necessary for patients with stage IA1-IIA1 cervical cancer after laparoscopic hysterectomy, 221 patients were retrospectively analyzed. Sixty-two of them were treated with laparoscopic hysterectomy and adjuvant radiotherapy (group A), 115 underwent open surgery (group B) and 44 received laparoscopic hysterectomy alone (group C). Results showed that the 3-year local recurrence-free survival (LRFS) rates of group A, B and C were 98.4%, 97.4% and 86.4%, respectively. The LRFS rates of group A and B surpassed C (A vs. B, p=0.634; A vs. C, p=0.011; B vs. C, p=0.006). The inter-group differences of 3-year overall survival (OS) and distant metastasis free survival (DMFS) were not statistically significant. In subgroup analysis of stage IB disease, the 3-year LRFS rates of group A, B and C were 100%, 98.8% and 83.1%, the 3-year OS rates of group A, B and C were 100%, 98.9% and 91.5%, respectively. The 3-year LRFS and OS rates of group A and B were significantly superior to group C (p<0.05). Our findings suggest that adjuvant radiotherapy can reduce the risk of recurrence for women with early-stage cervical cancer after laparoscopic hysterectomy and bring survival benefits for patients with stage IB disease.
Occurrence and Prevention of Delayed Autonomous Selfing in Salvia umbratica (Lamiaceae)

Delayed autonomous selfing (DAS) provides reproductive assurance under conditions of pollinator and/or pollen-limitation. Few plant species have been investigated to determine if DAS is terminated when a flower is sufficiently pollinated by a pollen vector, thereby saving plant resources for other purposes. We examined this possibility in bumblebee-pollinated Salvia umbratica. We first showed that DAS resulting in high fruit set (100%) and seed set (>80%) per flower occurred in the absence of insect pollinators by means of style recurvature and was completed in 94% of flowers 72 h after they opened. In contrast, in flowers pollinated immediately after opening, DAS was prevented by corollas dropping away before styles recurve toward the upper thecae. We next showed that hand-pollination of flowers immediately after they opened resulted in high fruit set (100%) and seed set (>80%) when 5–10 pollen grains or more were deposited on their stigmas, whereas fruit set and seed set were reduced to 45.00 and 22.50%, respectively, when pollen loads were reduced to 1–3 pollen grains. Finally, we showed that on average single pollinator visits deposited 26 pollen grains on stigmas of flowers that had just opened, which is more than enough to ensure high fruit and seed set. Our results indicate that flower longevity is highly correlated with the pollinator environment and female fitness of S. umbratica, with extended flower longevity allowing DAS to occur being advantageous when pollinators are absent, while reduced floral longevity and prevention of DAS being favored when flowers are pollinated by pollinators. Thus, flower longevity in S. umbratica varies so as to optimize reproductive output and resource efforts, and is dependent on the availability and effectiveness of pollinators to pollinate flowers.
Genetically Determined Chronic Low-Grade Inflammation and Hundreds of Health Outcomes in the UK Biobank and the FinnGen Population: A Phenome-Wide Mendelian Randomization Study

Background C-reactive protein (CRP) has been used as a biomarker of chronic low-grade inflammation in observational studies. We aimed to determine whether genetically determined CRP was associated with hundreds of human phenotypes to guide anti-inflammatory interventions. Methods We used individual data from the UK Biobank to perform a phenome-wide two-stage least squares (2SLS) Mendelian randomization (MR) analysis for CRP with 879 diseases. Summary-level data from the FinnGen consortium were utilized to perform phenome-wide two-sample MR analysis on 821 phenotypes. Systematic two-sample MR methods included MR-IVW, MR-WME, MR-Mod, and MR-PRESSO as sensitivity analyses combined with multivariable MR to identify robust associations. Genetic correlation analysis was applied to identify shared genetic risks. Results We found genetically determined CRP was robustly associated with 15 diseases in the UK Biobank and 11 diseases in the FinnGen population (P < 0.05 for all MR analyses). CRP was positively associated with tongue cancer, bronchitis, hydronephrosis, and acute pancreatitis and negatively associated with colorectal cancer, colon cancer, cerebral ischemia, electrolyte imbalance, Parkinson’s disease, epilepsy, anemia of chronic disease, encephalitis, psychophysical visual disturbances, and aseptic necrosis of bone in the UK Biobank. There were positive associations with impetigo, vascular dementia, bipolar disorders, hypercholesterolemia, vertigo, and neurological diseases, and negative correlations with degenerative macular diseases, metatarsalgia, interstitial lung disease, and idiopathic pulmonary fibrosis, and others. in the FinnGen population. The electrolyte imbalance and anemia of chronic disease in UK Biobank and hypercholesterolemia and neurological diseases in FinnGen pass the FDR corrections. Neurological diseases and bipolar disorders also presented positive genetic correlations with CRP. We found no overlapping causal associations between the populations. Previous causal evidence also failed to support these associations (except for bipolar disorders). Conclusions Genetically determined CRP was robustly associated with several diseases in the UK Biobank and the FinnGen population, but could not be replicated, suggesting heterogeneous and non-repeatable effects of CRP across populations. This implies that interventions at CRP are unlikely to result in decreased risk for most human diseases in the general population but may benefit specific high-risk populations. The limited causal evidence and potential double-sided effects remind us to be cautious about CRP interventions.
The Benefits of Forgiveness at Work: A Longitudinal Investigation of the Time-Lagged Relations Between Forgiveness and Work Outcomes

Forgiveness has received increasing attention in the work context. Although recent cross-sectional studies have found a positive link between forgiveness and work outcomes, further research examining the temporal dynamics between these variables is needed to establish causality. This preregistered panel study investigated the time-lagged relations between forgiveness and work outcomes, and specifically addressed the question whether forgiving a coworker benefits work outcomes. Longitudinal survey data were collected at four time points among 139 Chinese employees working at least 20 hours per week. Results from cross-lagged panel models revealed that forgiving an offending coworker with whom one has a relatively good work relationship predicted better work outcomes (i.e., higher job satisfaction, higher work engagement, and lower burnout) over time, while controlling for perceived severity of the offense. Evidence for the reverse effect (with work outcomes predicting forgiveness) was not found. Our findings thus suggest that forgiveness facilitates well-being-related work outcomes. Implications for a better understanding of forgiveness in work relationships are discussed.
When Music Speaks: An Acoustic Study of the Speech Surrogacy of the Nigerian Dùndún Talking Drum

Yorùbá dùndún drumming is an oral tradition which allows for manipulation of gliding pitch contours in ways that correspond to the differentiation of the Yorùbá linguistic tone levels. This feature enables the drum to be employed as both a musical instrument and a speech surrogate. In this study, we examined four modes of the dùndún talking drum, compared them to vocal singing and talking in the Yorùbá language, and analyzed the extent of microstructural overlap between these categories, making this study one of the first to examine the vocal surrogacy of the drum in song. We compared the fundamental frequency, timing pattern, and intensity contour of syllables from the same sample phrase recorded in the various communicative forms and we correlated each vocalization style with each of the corresponding drumming modes. We analyzed 30 spoken and sung verbal utterances and their corresponding drum and song excerpts collected from three native Yorùbá speakers and three professional dùndún drummers in Nigeria. The findings confirm that the dùndún can very accurately mimic microstructural acoustic temporal, fundamental frequency, and intensity characteristics of Yorùbá vocalization when doing so directly, and that this acoustic match systematically decreases for the drumming modes in which more musical context is specified. Our findings acoustically verify the distinction between four drumming mode categories and confirm their acoustical match to corresponding verbal modes. Understanding how musical and speech aspects interconnect in the dùndún talking drum clarifies acoustical properties that overlap between vocal utterances (speech and song) and corresponding imitations on the drum and verifies the potential functionality of speech surrogacy communications systems.
PSIXPORT: Mobile App for Ecological Momentary Assessment of Psychological Dimensions in Sport Injury

Retrospective self-reports have been commonly used to assess psychological variables such as feelings, thoughts, or emotions. Nevertheless, this method presents serious limitations to gather accurate information about variables that change over time. The Ecological Momentary Assessment (EMA) approach has been used to deal with some of the limitations these retrospective assessment methods present, and for gathering real-time information about dynamic psychological variables, such as feelings, thoughts, or behaviors. In the sports injury rehabilitation context, athletes' thoughts, feelings, behaviors, and pain perceptions during the rehabilitation process can influence the outcomes of this process. These responses change over different stages of the rehabilitation and taking them into account can help therapists to adapt the rehabilitation process and increasing their effectiveness. With this aim, an EMA mobile app (PSIXPORT) was designed to gather real-time information about severely injured athletes' cognitive appraisals, emotional responses, behaviors, and pain perceptions during their rehabilitation process. The goals of this study were to evaluate Psixport's ability to gather real-time information about injured athletes' psychological responses during the rehabilitation, to test the users' perceived usability of Psixport, and to compare the reliability and differences between real-time data gathered with Psixport and the data gathered through the one-time retrospective method. Twenty-eight severely injured athletes (10 men and 18 women) were assessed using Psixport, a retrospective questionnaire, and the uMARS usability test. Results showed that Psixport can be considered as a good tool to gather information about injured athletes' cognitive appraisals, emotional responses, behaviors, and pain perceptions. Moreover, multiple data assessments gathered with the app showed to be more accurate information about injured athletes' psychological responses than one-time retrospective reports.
BETting on a Transcriptional Deficit as the Main Cause for Cornelia de Lange Syndrome

Cornelia de Lange Syndrome (CdLS) is a human developmental syndrome with complex multisystem phenotypic features. It has been traditionally considered a cohesinopathy together with other phenotypically related diseases because of their association with mutations in subunits of the cohesin complex. Despite some overlap, the clinical manifestations of cohesinopathies vary considerably and, although their precise molecular mechanisms are not well defined yet, the potential pathomechanisms underlying these diverse developmental defects have been theoretically linked to alterations of the cohesin complex function. The cohesin complex plays a critical role in sister chromatid cohesion, but this function is not affected in CdLS. In the last decades, a non-cohesion-related function of this complex on transcriptional regulation has been well established and CdLS pathoetiology has been recently associated to gene expression deregulation. Up to 70% of CdLS cases are linked to mutations in the cohesin-loading factor NIPBL, which has been shown to play a prominent function on chromatin architecture and transcriptional regulation. Therefore, it has been suggested that CdLS can be considered a transcriptomopathy. Actually, CdLS-like phenotypes have been associated to mutations in chromatin-associated proteins, as KMT2A, AFF4, EP300, TAF6, SETD5, SMARCB1, MAU2, ZMYND11, MED13L, PHIP, ARID1B, NAA10, BRD4 or ANKRD11, most of which have no known direct association with cohesin. In the case of BRD4, a critical highly investigated transcriptional coregulator, an interaction with NIPBL has been recently revealed, providing evidence on their cooperation in transcriptional regulation of developmentally important genes. This new finding reinforces the notion of an altered gene expression program during development as the major etiological basis for CdLS. In this review, we intend to integrate the recent available evidence on the molecular mechanisms underlying the clinical manifestations of CdLS, highlighting data that favors a transcription-centered framework, which support the idea that CdLS could be conceptualized as a transcriptomopathy.