Miracle-dz/UniFAR-FTUs huggingface dataset:
Cyclin D 3 coordinates the cell cycle during differentiation to regulate erythrocyte size and number Citation

Citation Sankaran, V. G. , L. S. Ludwig, E. Sicinska, J. Xu, D. E. Bauer, J. C. Eng, H. C. Patterson, et al. “Cyclin D3 Coordinates the Cell Cycle During Differentiation to Regulate Erythrocyte Size and Number. ” Genes & Development 26, no. 18 (September 15, 2012): 2075–2087. Copyright © 2012 by Cold Spring Harbor Laboratory Press As Published http://dx.doi. org/10.1101/gad.197020. 112 Publisher Cold Spring Harbor Laboratory Press
Assessment of Static Positioning Accuracy Using Low-Cost Smartphone GPS Devices for Geodetic Survey Points’ Determination and Monitoring

Recent developments enable to access raw Global Navigation Satellite System (GNSS) measurements of mobile phones. Initially, researchers using signals gathered by mobile phones for high accuracy surveying were not successful in ambiguity fixing. Nowadays, GNSS chips, which are built in the latest smartphones, deliver code and primarily carrier phase observations available for detailed analysis in post-processing applications. Therefore, we decided to check the performance of carrier phase ambiguity fixing and positioning accuracy results of the latest Huawei P30 pro smartphone equipped with a dual-frequency GNSS receiver. We collected 3 h of raw static data in separate sessions at a known point location. For two sessions, the mobile phone was mounted vertically and for the third one—horizontally. At the same time, a high-class geodetic receiver was used for L1 and L5 signal comparison purposes. The carrier phase measurements were processed using commercial post-processing software with reference to the closest base station observations located 4 km away. Additionally, 1 h sessions were divided into 10, 15, 20 and 30 min separate sub-sessions to check the accuracy of the surveying results in fast static mode. According to the post-processing results, we were able to fix all L1 ambiguities based on Global Positioning System (GPS)-only satellite constellation. In comparison to the fixed reference point position, all three 1 h static session results were at centimeters level of accuracy (1–4 cm). For fast static surveying mode, the best results were obtained for 20 and 30 min sessions, where average accuracy was also at centimeters level.
Advancing Qualitative Entrepreneurship Research: Leveraging Methodological Plurality for Achieving Scholarly Impact

This editorial aims to advance the use of qualitative research methods when studying entrepreneurship. First, it outlines four characteristics of the domain of entrepreneurship that qualitative research is uniquely placed to address. In studying these characteristics, we urge researchers to leverage the plurality of different qualitative approaches, including less conventional methods. Second, to help researchers develop high-level theoretical contributions, we point to multiple possible contributions, and highlight how such contributions can be developed through qualitative methods. Thus, we aim to broaden the types of contributions and forms that qualitative entrepreneurship research takes, in ways that move beyond prototypical inductive theory-building.
Regional atmospheric response to the Benguela Niñas

We investigate how the atmosphere is affected by the cold sea surface temperature (SST) anomalies of the Benguela Niñas using reanalysis data and a high‐resolution atmospheric model. A composite analysis of reanalysis data based on five Benguela Niña events (5 years out of 39 years for 1979–2017) reveals that the rainfall along the Angolan coast is reduced significantly and other anomalies of precipitation are detected over the African continent and equatorial Atlantic. Those anomalies can be explained by the anomalies of vertically‐integrated moisture flux (VIMF) and its divergence and convergence. Additionally, the Namibian low‐level cloud and sea level pressure (SLP) are enhanced around the ABFZ by the Benguela Niñas. A simulation of the model forced by the cold SST anomalies of the Benguela Niñas reproduces the reduction (enhancement) of rainfall and VIMF divergent (convergent) anomaly over the Angolan coastal region (Gulf of Guinea). However, the other anomalies over the African continent are not significant. It is suggested that the effects of the Benguela Niñas are limited along southwestern coast of Africa. Composite analysis of reanalyses of rainfall anomalies associated with Benguela Niña events shows pattern over the other regions which might be induced by larger‐scale atmospheric anomaly. This large‐scale atmospheric anomaly can be linked with the South Atlantic Anticyclone and/or forced by the teleconnection from the tropical Pacific, for instance. The increment of the Namibian low‐level cloud and SLP is simulated by the numerical experiments consistently. The low‐level cloud becomes more frequent between 950 and 900 hPa and the radiative cooling by longwave radiation is reinforced during the Benguela Niñas events. In contrast, the cloud formation around 850 hPa is reduced and radiative cooling is weakened. It is indicated that this change in the cooling rate possibly induces the strengthening in the inversion layer over the cold SST anomalies.
CCAAT / enhancer-binding protein activates the Runx 2-mediated transcription of mouse osteocalcin II promoter

CCAAT/enhancer-binding proteins (C/EBPs) are involved in the regulation of cell proliferation, differentiation, and control of metabolic function. Although the roles of C/EBPs in osteoblasts are largely unknown, both C/EBP and have been shown to enhance rat osteocalcin promoter activity through the synergistic activation of Runx2 at the C/EBP element. Here we show that in the mouse, C/EBP increases the expression of osteocalcin whereas C/EBP does not. This increased expression was found to occur at the transcriptional level, as demonstrated by the increased transcriptional activity from mouse osteocalcin II (OG2) promoter by C/EBP . Although we found three putative C/EBP sites in the −637/±34 region of the OG2 promoter, none of these sites showed binding activity with in vitro translated C/EBP proteins. Notably, we show that C/EBP physically interacts with Runx2 and that C/EBP overexpression increases binding between the Runx2–C/EBP complex and the OSE2 element, a critical osteoblast-specific cis-acting element in the OG2 promoter. Consistent with these DNA binding data, a mutation in OSE2 abrogated the stimulatory effect of C/EBP on this promoter activity. Finally, chromatin immunoprecipitation analysis in MC3T3-E1 cells showed in vivo occupancy of the OG2 promoter by Runx2 and C/EBP . In conclusion, C/EBP was found to regulate mouse osteocalcin OG2 promoter activity indirectly by interacting with Runx2 in the context of the OSE2 element and this subsequently resulted in the cooperative activation of the OG2 promoter. Journal of Molecular Endocrinology (2006) 36, 531–546
Assessing the EU’s 2030 Climate and Energy Policy Framework: Incremental change toward radical transformation?

This article provides a comprehensive overview of the changes to European Union (EU) climate and energy law brought about by the 2030 Climate and Energy Policy Framework. It explains the Framework’s background and objectives, and analyses its main legal instruments. It argues that the 2030 Framework incrementally develops and enhances EU climate law without revolutionizing it, advancing in particular its proceduralization. The article also explores the prospects for future change of the 2030 Framework towards more radical transformation in light of the European Green Deal and the ongoing COVID-19 pandemic.
A Photometric and Spectroscopic Study of Dwarf and Giant Galaxies in the Coma Cluster. IV. The Luminosity Function

A large spectroscopic survey is constructed of galaxies in the Coma Cluster. The survey covers a wide area (1 deg2) to deep magnitudes (R ~ 19.5), covering both the core (high density) and outskirts (intermediate to low density) of the cluster. The spectroscopic sample consists of a total of 1191 galaxies, of which 760 are confirmed members of the Coma Cluster. A statistical technique is developed to correct the spectroscopic sample for incompleteness. The corrected sample is then used to construct an R-band luminosity function (LF) spanning a range of 7 mag (-23 < MR - 5 log h65 < -16) at both the core and outskirts of the cluster. The R-band LF for the entire Coma Cluster, fitted to Schechter form, gives M = -21.79 + 5 log h65 and α = -1.18. Dependence of the LF on local environment in Coma is explored. The LFs are found to be the same, within the errors, between the inner and outer regions and close to those from recent measurements for field galaxies. This is remarkable given the variation in the spectral types of galaxies between field and cluster environments. The steep faint-end slope for the LFs, observed in previous studies using photometric surveys, is not found here. However, the LF in this study is only measured to MR = -16, compared to much deeper limits (MR ~ -12) achieved in photometric surveys. The total B-band LF for the Coma Cluster, fitted to a Schechter form, is M = -19.95 + 5 log h65 and α = -0.96. This also shows a dip at M = -18 mag, in agreement with previous studies. The implications of this feature are discussed. The LF is studied in B-R color intervals and shows a steep faint-end slope for red (B-R > 1.35) galaxies, at both the core and outskirts of the cluster. This population of low-luminosity red galaxies has a higher surface density than the blue (B-R < 1.35) star-forming population and dominates the faint end of the Coma Cluster LF. It is found that the relative number of high surface brightness galaxies is larger at the cluster core, implying the destruction of low surface brightness galaxies in the dense core environment.
Bike Sharing and the Economy, the Environment, and Health-Related Externalities

In recent years, bike-sharing has experienced rapid development; however, controversies about the externalities of bike-sharing programs have arisen as well. While bike-sharing programs have impacts on traffic, the environment, and public health, the social impacts, the management, and sustainable development of bike-sharing has also been of interest. The debate regards whether there are externalities, as well as whether and how such externalities can be determined. Based on the rapidly diffused bike-sharing in China, this paper quantitatively explores bike-sharing externalities. Specifically, this paper estimates the impacts of bike-sharing on the economy, energy use, the environment, and public health. The empirical results show that bike-sharing programs have significant positive externalities. The bike-sharing systems can provide urban residents with a convenient and time-saving travel mode. We find that the bike-sharing dramatically decreases traffic, reduces energy consumption, decreasing harmful gas emissions, improves public health generally, and promotes economic growth. This study contributes to a better comprehension of the externalities of bike-sharing and provides empirical evidence of the impacts of bike-sharing. Findings suggest that bike-sharing can play a critical role in the process of urban transportation development and provide information useful for urban transportation policies.
Multifractals and resolution-independent remote sensing algorithms: The example of ocean colour

We argue that geophysical and geographical fields are generally characterised by wide range scaling implying systematic, strong (power law) resolution dependencies when they are remotely sensed. The corresponding geometric structures are fractal sets; the corresponding fields are multifractals. Mathematically, multifractals are measures that are singular with respect to the standard Lebesgue measures; therefore, they are outside the scope of many of the methods of classical geostatistics. Because the resolution of a measurement is generally (due to technical constraints) much larger than the inner scale of the variability/scaling, the observations will be fundamentally observer dependent; hence, standard remote sensing algorithms that do not explicitly take this dependence into account will depend on subjective resolution-dependent parameters. We argue that, on the contrary, the resolution dependence must be systematically removed so that scale-invariant algorithms independent of the observer can be produced. We illustrate these ideas in various ways with the help of eight-channel, 7 m resolution remote ocean colour data (from the MIES II sensor) over the St Lawrence estuary. First, we show that the data is indeed multiscaling over nearly four orders of magnitude in scale, and we quantify this using universal multifractal parameters. With the help of conditional multifractal statistics, we then show how to use multifractals in various practical ways such as for extrapolating from one resolution to another or from one location to another, or to correcting biases introduced when studying extreme, rare phenomena. We also show how the scaling interrelationship of surrogate and in situ data can be handled using vector multifractals and examine the resolution dependence of principle components in dual wavelength analyses. Finally, we indicate why the standard ocean colour algorithms have hidden resolution dependencies, and we show how they can (at least in principle) be removed.
Double gendered: public views on women’s and men’s migration in Armenia

ABSTRACT Globally, the share of women among international labour migrants has risen dramatically in the past several decades, but in many patriarchal settings with traditionally high levels of men’s out-migration the levels of women’s migration remain low. Using data from a nationally representative survey conducted in one such setting, Armenia, I examine public perceptions of various consequences of migration with what I define as a double-gendered analytic lens: looking at female and male migration through women’s and men’s eyes. The statistical tests find that overall female migration tends to be assessed more negatively than male migration, but they also point to instructive gender differences in such assessments. Thus, in general, men tend to see female migration more negatively and male migration more positively, compared to women. Yet, while this gender divide is consistently present in views on various consequences of male migration, it is not statistically noticeable in views on the effects of female migration on family duties and relationships or on sexual matters after controlling for other factors. These patterns illustrate the gendered complexity of public attitudes toward international labour migration and help to understand its dynamics and prospects in this and similar migrant-sending contexts.
Were universal banks more vulnerable to banking failures? Evidence from the 1931 German banking crisis

This paper examines the 1931 German banking crisis using a bank-level data set. It specifically focuses on the link between banking structure and financial stability. The universality of banks, a key characteristic of the German banking system, is shown to increase the probability of bank failure after controlling for other bank-level characteristics and macroeconomic variables.
ASSOCIATION OF DIABETIC RETINOPATHY WITH INCREASED BLOOD LEVEL OF HBA1C.

Objective: To determine frequency of diabetic retinopathy associated with high level of glycosylated hemoglobin HbA1c in blood. Design & duration: This is a cross sectional study of observational type completed in eight months duration. Setting: Study was conducted at ophthalmology department of Bahawal Victoria Hospital Bahawalpur. Patients & methods: Diabetic patients presenting to out-patient door of ophthalmology department of study hospital were selected via non probability consecutive sampling technique. Sample size was calculated using WHO sample size calculator. Retinal examination was done in all patients. Those having retinopathy in study group were put into separate group. Blood level of HbA1c was tested in all cases of study group. Frequency of proliferative and non-proliferative diabetic retinopathy was determined. Consent was taken from all cases in study group and from ethical committee of the study institution as well. Chi square test was applied. P-value less than 0.05 was taken significant. Results: Total 180 diabetic patients were studied out of them 58.3% were male and 41.7% were female. Mean age of patients was 51±11.3 years. Mean HbA1c level was 8.3±1.6. Proliferative retinopathy was observed in 36.2% and non-proliferative retinopathy was seen in 63.8% out of total 47 cases with retinopathy. Conclusion: Diabetic retinopathy is associated with high blood level of glycosylated hemoglobin and nonproliferative retinopathy is more common than proliferative retinopathy.
Effect of Climate Change and CO 2 Concentration on Growth and Yield of Rice and Wheat in Punjab: Simulations Using CSM-CERES-Rice and CSM-CERES-Wheat Models

Recent trends of a decline or stagnation in the yield of rice and wheat in rice-wheat (RW) systems of the Indo-Gangetic Plains (IGP) have raised serious concerns about the regional food security. The effect of future climate change on crop production adds to this complex problem. The validated CSM-CERES-Rice and CSM-CERES-Wheat (Ver. 4.0) data were used to test the sensitivity of the models in Punjab, India. The models were sensitive to climatic parameters (temperature, CO 2 concentration, solar radiation and rainfall) on yields of both crops. Simulated rice yields were sensitive to weather as there was 13% less yield of rice in 1999 than in 2001. Similarly, simulated wheat yields were also sensitive to weather, with the highest yield in 2001, and the lowest in 2003. Increments in both maximum and minimum temperatures by 4°C, decreased rice yield by 34% and wheat yield by 4% as compared to base scenario with current weather data. By increasing 4°C for both maximum and minimum temperature along with an increase in solar radiation by 1MJ/m 2 /day, rice yield decreased by 32% as compared to base scenario while wheat yields were not affected. With the increase in maximum and minimum temperatures by 4°C, and also an increase in CO 2 concentration by 20 ppm from the standard CO 2 concentration of 335 ppm, the reduction in rice yield was 33%, but in wheat yield was only 3%. Rainfed wheat yield increased by 7%, by increasing daily rainfall by 1.5 times, and by 13%, by doubling the rainfall, both after 96 days of sowing (DAS) to maturity. Lowering rainfall to zero, for each day after 96 DAS to until maturity reduced wheat yield by 18%. The increasing maximum and minimum temperatures irrespective of whether the CO 2 concentration increased or not, seemed to have more adverse effects on rice than to wheat. Simulations demonstrated that CSM-CERES-Rice and CSM-CERES- Wheat are sensitive to CO 2 and climatic parameters, and can be used to study the impact of future climate change on rice and wheat productivity in RW systems in Asia. Key words: CSM-CERES-Rice, CSM-CERES-Wheat, climate change, yield, phenology J. Inst. Agric. Anim. Sci. 27:103-110 (2006)
Relations of Approaches to Learning with Perceptions of Learning Environment and Goal Orientations

Keywords This study aimed to investigate the relationships among high school students’ approaches to learning science, perceptions of classroom learning environment, and achievement goals. The participants of the study included 800 high school students from 9th to 12th grade in three public schools. A conceptual model constructed based on literature were tested with structural equation modeling. The analysis of the data collected in this study supported the hypothesized model. The findings revealed that students’ perceptions of classroom environment and masteryapproach goals affected positively their deep approaches to learning science. In this study, the mediated effect of masteryapproach goals was observed. Mastery–approach goals increased the effect of the perceptions of classroom learning environment on deep approaches to learning science. Moreover, it was found that performance-approach, performance-avoidance and masteryavoidance goals were positively associated with surfaceapproaches to learning science. Finally, in this study, the positive effect of students’ perceptions of classroom learning environment on their mastery-approach goals was observed. The implications of the study for teaching and learning were discussed.
Anthropometric profile and abdominal adiposity of school children aged between 6 and 10 years in southern Brazil Perfil antropométrico e adiposidade abdominal de escolares entre 6 a 10 anos de idade do Sul do Brasil

The aims of the present study were to assess the association of anthropometric measures with body mass index (BMI) and to verify the presence of abdominal adiposity in school children. This is a cross-sectional study conducted with 4,964 school children between 6 and 10 years of age registered in 345 schools from eight municipalities of the state of Santa Catarina (Brazil). The independent variables used were the following: subscapular (SSF) and triceps skinfold (TSF) thickness, arm circumference (AC), waist circumference (WC), hip circumference (HC), waist-to-hip ratio (WHR), and waist-to-height ratio (WHtR). BMI was used as the dependent variable. Unadjusted and adjusted associations were estimated using linear regression and expressed as a regression coefficient (β). All anthropometric measurements were controlled during adjusted analysis to remain within the p < 0.20 model. Abdominal adiposity was defined as WHtR ≥ 0.5. The mean BMI was 17.4 kg/m2 (SD = 2.8) in males and 17.2 kg/m2 (SD = 2.8) in females. The mean anthropometric measurements for males and females respectively were as follows: SSF = 7.2 and 8.3mm; TSF = 10.8 and 12.6mm; AC = 20.0 and 20.2cm; WC = 60.1 and 58.5cm; HC = 71.3 and 71.9cm; WHR = 0.84 and 0.81; WHtR = 0.45 and 0.44. All anthropometric measurements were positively associated with BMI in the unadjusted analysis of both sexes. In the adjusted analysis, associations among males were as follows: SSF (β = 0.05), AC (β = 0.17), WC (β = 0.19), and WHtR (β = 30.5). Associations among females were as follows: SSF (β = 0.19), AC (β = 0.17), WC (β = 0.13), WHR (β = -6.2), and WHtR (β = 32.1). The prevalence of abdominal adiposity was 11.9%. It was concluded that the anthropometric indicators SSF, AC, WC, and WHtR had a satisfactory relationship with BMI in school children of both sexes. These measurements could be used, in addition to BMI, to determine total and central adiposity.