Miracle-dz/UniFAR-FTUs huggingface dataset:
Severe hypokalemia in the emergency department: A retrospective, single‐center study

Hypokalemia is one of the most common problems in the emergency department (ED). Severe hypokalemia, defined as a serum potassium level ≤2.5 mEq/L, is a relatively uncommon electrolyte disorder, and few studies have reported its prevalence, etiology, symptoms, and management in the ED. Therefore, we aimed to investigate them in this study.
On Locking-free Methods for Isogeometric Large Deformation Analysis of Geometrically Exact 3D Timoshenko Beams

In this thesis the geometrically exact 3D shear-flexible beam model is discretized with the Lagrangian and the NURBS basis functions, and has been used as a basis to develop a family of locking-free NURBS-based elements. This beam model has no restrictions with respect to the size of displacements, rotations and deformations, and is thus well accommodated for large deformation analyses. In the C 0-continuous Lagrange element, numerical locking is overcome by reduced integration. However, for the higher continuous NURBS elements, there exists at the present time no element-by-element Gaussian quadrature rule which effectively alleviates locking. Instead, by a patch-wise approach a selective reduced integration rule has been proposed, and the resulting elements are free for transverse shear and membrane locking. The performance is evaluated on a range of numerical tests and compared to the conventional reduced integration rule. For comparison, also the standard Lagrange interpolated elements have been tested in parallel.
The effects of combined digital and human advisory services on reducing nitrogen fertilizer use: lessons from China’s national research programs on low carbon agriculture

ABSTRACT In the context of emerging digital advisory services that can make a potential difference in sustainable farming practices, this article analyzes the connection between on-farm human interaction and digital advice. Based on an experimental case from China’s largest ever national research initiative on reducing agrochemical use in agricultural production, this study found that introducing university facilitators to promote ICT-based advisory services is conducive to site-specific fertilizer use. Through interactions with farmers, the facilitator complemented digital advisory services to achieve optimal N-fertilizer use in maize production. Digital service providers favoured large farms and usually would not service smallholder farmers, thus limiting the potential of digital advisory services. A main theoretical implication is that digital technology should not be completely relied upon because it may only give part of the answer. A human facilitator still plays an important role in integrating new technologies in interaction with farmers. Human advisory services can interpret or translate data to improve farmers’ decision-making, going beyond the advisory capacity of ICT technology. This is an important policy implication for China regarding its national research policies on agricultural sustainability and digital advisory services, and also calls for further research on interactions between digital and human advisory services.
A Profile of the Steel Industry: Global Reinvention for a New Economy

The steel mill and the auto plant were the icons of the 20th-century industrial economy. By the early 21st century, many people viewed steel as Big, Ugly, and Gone to China. Not so. In manufacturing, The World Is Not Flat! The steel industry has continuously been forced to remake itself. This book describes those developments and dynamics
Anti-Inflammatory and Anti-Oxidative Effects of Isorhamnetin for Protection Against Lung Injury in a Rat Model of Heatstroke in a Dry-Heat Environment

Background Isorhamnetin is a natural flavonoid compound with anti-inflammatory and antioxidant properties. However, its roles in alleviating lung injury associated with heatstroke remain unclear. Therefore, this study aimed to evaluate the protective effects of different isorhamnetin doses on lung injury in heatstroke rat models exposed to a dry-heat environment. Material/Methods Fifty Sprague-Dawley rats were randomly divided into 5 groups: normal control (0.9% saline), heatstroke (0.5% CMCNa), and isorhamnetin (25, 50, and 100 mg/kg) groups; treatments were administered by gavage daily for 7 days. All rats, except those in the control group, were exposed to a dry-heat environment (41±1°C, 10±2% relative humidity) for 150 min to induce heatstroke. Pathological changes, ultrastructure, edema, inflammation, and oxidative stress in the lungs were assessed. Results Compared with the heatstroke group, rats treated with 100 mg/kg isorhamnetin showed amelioration of histopathological and ultrastructural changes in the lungs; decreased lung injury scores (P<0.05) and wet/dry weight ratios (P<0.01); lower levels of phospho-nuclear factor-κB (P<0.05), high-mobility group box 1 (P<0.01), tumor necrosis factor-α (P<0.01), interleukin (IL)-1β (P<0.01), and IL-6 (P<0.01); lower malondialdehyde contents (P<0.01); and higher superoxide dismutase (P<0.01) and catalase activities (P<0.05). Conclusions In a dry-heat environment, isorhamnetin protected against lung injury in heatstroke rat models via anti-inflammatory and anti-oxidative mechanisms.
Knowledge and Data-Driven Framework for Designing a Computerized Physician Order Entry System

A major concern related to the healthcare industry is uniformity in healthcare delivery. There is considerable variation in the diagnosis and treatment of patients depending on the experience and expertise of the doctors. Information technology can play a major role in addressing this issue. Research investigating the use of data-driven approaches and knowledge-driven clinical pathways to achieve uniformity in the delivery of healthcare is ongoing. Specifically, the integration of data and knowledge-driven approaches can be used to ensure uniformity in the delivery of patient care, thus avoiding inappropriate variance. The data-driven approach can utilize the bulk of medical data being generated. The knowledge-driven approach in the form of clinical pathways incorporates evidence-based care. In this context, knowledge and data-driven computerized physician order entry (CPOE) systems are gaining importance in healthcare delivery systems. This paper proposes a knowledge and data-driven framework for a CPOE system. This work is based on a knowledge base populated with disease quadruples, each of which comprises a list of symptoms, tests, results, and medications for a particular disease. The data used in the proposed system are obtained from two datasets, namely, the MIMIC (Medical Information Mart for Intensive Care) and the Disease-Symptom Knowledge Database, which is based on the operational data of New York-Presbyterian Hospital (NYPH). We combined both datasets using the common attribute of disease to generate data with more attributes to aid decision making. This was performed with the help of specialists and clinical knowledge. The resulting patient data are further integrated with clinical pathways before the extraction of disease quadruples. The novelty of this work lies in the extraction of disease quadruples from the integration of patient data with clinical pathways. The list dynamically ranks each element of the quadruple based on its association score to facilitate the generation of prescription order sets for the CPOE. The effectiveness of the proposed system in providing uniform patient care delivery has been validated by experts. The proposed system can significantly improve patient safety and the quality of healthcare delivery due to the integration of data-driven capability with clinical pathways.
Choosing the right options trading strategy: Risk-return trade-off and performance in different market conditions

The investment decisions are subjected to risk and return of the financial asset. Options strategies help employ a suitable strategy to balance the risk-return trade-off. The study analyzes the risk-return trade-off of the long straddle, long strangle, long call butterfly (LCB), short straddle, short strangle, and short call butterfly (SCB) strategies. Moreover, it measures the impact of strategy risk and options premiums on strategy return using panel data analysis. Additionally, the study evaluates the performance of options strategies using the excess returns to risk approach under neutral and volatile market conditions. This paper considered companies of top-six sector indices of the National Stock Exchange from 2009 to 2020 and collected data of 18,720 option contracts and 3,744 observations for each strategy (22,464 observations). The study revealed that risks of long straddle and long strangle strategies have a positive impact, and options premiums negatively influence their payoff. ATM call premiums positively affect LCB payoff, while OTM and ITM call premiums positively influence SCB payoff. However, the risks of butterfly strategy did not influence its payoff. The risk of short straddle and short strangle strategies negatively influenced the payoff and were considered riskier strategies. Moreover, short straddle and short strangle strategies enhanced excess returns under both market conditions. The results would help the investors in choosing the appropriate strategy by analyzing the impact of risk on the payoff and the ability to enhance excess returns to the risk of various options strategies to incorporate in their investment.
Fashion Conscious Consumption and Consumer Perception: A Study in the Local Productive Arrangement of Clothing of Pernambuco

This study aims to analyze the relationship between the perception of corporate social responsibility actions (PCSRA) and the purchase of green products (PGP) on price sensitivity (PS) and the influence of these constructs on conscious consumption (CC). For this purpose, a descriptive quantitative study was carried out with fashion consumers of a Local Productive Clothing Arrangement in the Agreste area of Pernambuco, and the data was analyzed using Structural Equation Modeling. The results identified that PGP has an influence on PS and a negative relationship with CC. PCSRA, on the other hand, has a positive influence on CC, but not on PS, and the relationship between PS and CC was not significant. These results indicate that social aspects have a greater predominance over CC, and price does not seem to be a barrier to the consumer’s consciousness regarding the consumption of fashion products. This study innovates by bringing to debate the relationship between relevant constructs that have been investigated separately in the field of consumption.
Bicarbonate-Triggered In Vitro Capacitation of Boar Spermatozoa Conveys an Increased Relative Abundance of the Canonical Transient Receptor Potential Cation (TRPC) Channels 3, 4, 6 and 7 and of CatSper-γ Subunit mRNA Transcripts

Simple Summary The detection of sub-fertile boars has been a difficult task, and despite their prevalence being low, its impact is very significant because it implies economic drawbacks for artificial insemination (AI) centers and farms. Unfortunately, some crucial reproductive processes fall beyond the routine analysis performed in the porcine model, such as sperm capacitation, which is a necessary event for fertilization. A synergistic action of bicarbonate (HCO3−) with calcium (Ca2+) is needed to achieve capacitation. The transport of Ca2+ is mediated by CatSper channels and Canonical Transient Potential Channels (TRPC). We quantified mRNA transcripts of different subunits of CatSper (β, γ and δ) and TRPC (1, 3, 4, 6 and 7) before and after in vitro capacitation by HCO3− ions. Our results showed that in vitro capacitation using HCO3− increases the relative abundance of mRNA transcripts of almost all subunits of Ca2+ channels, except CatSper-δ and TRPC1, which were significantly reduced. More studies are needed to elucidate the specific roles of the TRPC channels at a physiological and functional level. Abstract Sperm capacitation is a stepwise complex biochemical process towards fertilization. It includes a crucial early calcium (Ca2+) transport mediated by CatSper channels and Canonical Transient Potential Channels (TRPC). We studied the relative abundance of mRNA transcripts changes of the CatSper β, γ and δ subunits and TRPC-channels 1, 3, 4, 6 and 7 in pig spermatozoa, after triggering in vitro capacitation by bicarbonate ions at levels present in vivo at the fertilization site. For this purpose, we analyzedfive5 ejaculate pools (from three fertile adult boars) before (control-fresh samples) and after in vitro exposure to capacitation conditions (37 mM NaHCO3, 2.25 mM CaCl2, 2 mM caffeine, 0.5% bovine serum albumin and 310 mM lactose) at 38 °C, 5% CO2 for 30 min. In vitro capacitation using bicarbonate elicits an increase in the relative abundance of mRNA transcripts of almost all studied Ca2+ channels, except CatSper-δ and TRPC1 (significantly reduced). These findings open new avenues of research to identify the specific role of each channel in boar sperm capacitation and elucidate the physiological meaning of the changes on sperm mRNA cargo.
Inspiration on social media: Applying an entertainment perspective to longitudinally explore mental health and well-being

The conditions under which social media use impacts well-being and mental health are complex. The current 10-day longitudinal quasi-experiment (student sample, N = 111) applied an entertainment theory lens to explore the effects of active posting and engaging with hedonic or inspiring Facebook content (vs. passive browsing) on young people’s eudaimonic well-being (levels of connectedness to humanity, love, compassion, presence of meaning) and mental health (anxiety and depressive symptoms). The results provide tentative evidence that finding and sharing inspiring content to a Facebook group increased love and compassion toward others over time. It also led to more compassion at the end of the study compared to participants who shared hedonic content. Although we did not find an increase in connectedness and meaningfulness over time for participants sharing content that they found inspiring, the latter also did not take away from those experiences, regardless of how they used it. Similarly, no decrease—but also no increase—in anxiety and depressive symptoms were found over time, regardless of condition. The study stresses the importance of better understanding the content young adults engage with on social media for their mental health and well-being.
How are the Sociolinguistic Competences applied in the English Textbook?

Promoting the sociolinguistic competences in the teaching process is vital since the students are required to use English for real-life communication. One of ways that teachers can do is by inserting sociolinguistic competences in their teaching materials. However, rarely did they focus on the sociolinguistic competences. Therefore, this content analysis research aims to void this gap by analyzing the use of sociolinguistic competences in the textbook entitled “Let’s Talk”. The result shows that the textbook has already applied the sociolinguistic competences in the dialogs including the social factors, speech functions, and Leech’s Politeness Principles (PP). To summarize, textbooks should provide more dialogue models with diverse sociolinguistic contexts for practicing interactional and transactional communication. At that time, the learners would have been exposed to learn effective language use, as well as fluency practice and language accuracy, as these are prerequisites for achieving communicative competence goals.
The Prevalence and Associated Infection Risk Factors of the Blood Protozoan Parasites among the Small Ruminants in the North Coast of Egypt

Several factors are affecting the productivity of small ruminants, infectious diseases and their causative pathogens are one of the most detrimental factors. Blood protozoan parasites are pathogens affecting small ruminants worldwide, particularly Egypt. Thus, the current study was done for detecting the prevalence of the blood protozoan parasites among small ruminants in the North Coast of Egypt. This was done through collecting 366 blood samples from four districts at Matrouh governorate. Microscopic examination of the Giemsa-stained blood smears was done to reveal the overall infection rate. Results showed a total prevalence of 68.30% (Babesia ovis, Theileria ovis. and Anaplasma ovis.). Sheep recorded a higher prevalence of 84.8% than that of goat. Females recorded the highest infection rate with a highly significant association with infection in relation to the open breeding (X2=72.501, P. value=0.000). The same significant result was observed with the presence of ticks on the examined animals (X2 =46.711, P. value=0.000). When summed up, we can conclude that the lack of vector control in Matrouh governorate, associated with a bad housing of herd, ignorance of the proper animal management, and the open breeding system are the reasons for the widespread infection with blood protozoan parasites among small ruminants.
The Impact of Teacher and School Factors on Teachers’ Perception of Their Personal and Group Organizational Citizenship Behaviors

ABSTRACT The purpose of this study is to examine the relationship between school ethical climate, organizational citizenship behavior and social loafing. The study participants included 878 teachers, 50 principals and 50 school counselors from 50 primary schools. The data analysis was based on multilevel SEM. The findings indicate different behavioral mechanisms between the individual and the group levels among teachers. A positive relation was found between personal organizational citizenship behavior and group organizational citizenship behavior, as well as a negative relation between group organizational citizenship behavior and social loafing. In practice, school leaders should encourage workgroups for maximizing school effectiveness.
The Intention to Use Blockchain in Indonesia Using Extended Approach Technology Acceptance Model (TAM)

Globalization has quickly transformed the economy and society, marked by the rapid integration of data and information, supply chains, and increasingly huge use of technology. The research aims to analyze the level of intention to use blockchain in Indonesia, especially the My-T Wallet developed by Tokoin using the Extended Technology Acceptance Model (TAM) approach. The research modifies the TAM by adding other variables that play an essential role in making decisions about using blockchain. The target population is that the respondents at least know about blockchain developments, in this case, My-T Wallet from Tokoin. The research obtains as many as 103 respondents who fill out the questionnaire through the purposive sampling technique. The data are collected through online surveys and analyzed using the Structural Equation Model (SEM) approach with the SmartPLS software. The findings highlight that the perception of the usefulness of the My-T Wallet application is most strongly influenced by public influence. Meanwhile, perceived ease of use is most influenced by the user interface in My-T Wallet. Then, the intention to use My-T Wallet application is strongly influenced by users’ positive behavior. On the other hand, the level of trust of application users must continuously be increased by paying more attention to government regulations and security aspects.
Characteristics of Visual Impairment and the Impact of Low Vision Assessment in a Tertiary Academic Hospital in Jordan

Purpose This project aims to describe the characteristics of patients with visual impairment referred from a tertiary academic hospital in Jordan for a comprehensive low vision evaluation and to study its impact on their functional needs. Methods A retrospective analysis of the records of 108 patients from the ophthalmology clinic at Jordan University Hospital over the period from January 2014 to December 2018 was performed. Gathered information included age, gender, clinical diagnosis, family history of ocular disease, and type of low vision aid prescribed and its impact on patients’ functional needs. Results The mean age was 44.64 years (range 4–88). Most participants were in the 19–60 years age group (50.0%). Fifty percent of the participants were the offspring of consanguineous marriages. The main cause of visual impairment in this cohort was retinitis pigmentosa, followed by diabetic retinopathy. The majority of low vision aids were prescribed for near distance tasks, and reading spectacles were the most prescribed visual aid. Eighty-nine percent of patients reported functional improvement and retained their visual aids upon follow-up. Conclusion Retinitis pigmentosa was the main cause of visual impairment in this cohort of patients referred from a tertiary academic hospital for low vision assessment. We report a consanguinity rate of 50%. The overwhelming majority of patients reported functional improvement and retained their visual aids upon follow-up. Awareness and integration of low vision services into a multidisciplinary approach and improving referral protocols is essential to better address the needs of patients with visual impairment. Familial counselling regarding consanguineous marriages and emerging research to treat inherited retinal diseases should be pursued.
Predictive Value of Elevated Neutrophil Gelatinase-Associated Lipocalin (NGAL) Levels for Assessment of Cardio–Renal Interactions among ST-Segment Elevation Myocardial Infarction Patients

Background: Elevated serum neutrophil gelatinase-associated lipocalin (NGAL) levels reflect both inflammatory reactions and renal tubular injury. Recently, associations with endothelial dysfunction and plaque instability were also proposed. We investigated the prognostic utility of elevated NGAL levels for renal and clinical outcomes among ST-segment elevation myocardial infarction (STEMI) patients treated with primary coronary intervention (PCI). Methods: We performed a prospective, observational, open-label trial. High NGAL was defined as values within the third tertile (>66 percentile). Results: A total of 267 patients were included (mean age 66 ± 14 years, 81% males). Short-term adverse outcomes were consistently increased in the high NGAL group with more acute kidney injury, lower mean left ventricular ejection fraction, higher 30-day mortality, and higher incidence for the composite outcome of major adverse cardiac events (MACE). In a multivariate logistic regression model, high NGAL emerged as a strong and independent predictor for MACE (OR 2.07, 95% CI 1.15–3.73, p = 0.014). Conclusions: Among STEMI patients undergoing primary PCI, elevated NGAL levels are associated with adverse renal and cardiovascular outcomes, independent of traditional inflammatory markers. Further studies are needed to assess the potentially unique role of NGAL in cardio–renal interactions.