Miracle-dz/UniFAR-FTUs huggingface dataset:
The Level of Brain-Derived Neurotrophic Factor and Tyrosine Kinase B Expression in Peripheral Blood of the Patients with Dermatomyositis

Objective: Brain-derived neurotrophic factor (BDNF) plays a well- established role in neuronal development and plasticity. Recently it has been speculated that BDNF may be involved in the pathogenesis of immune system diseases, because T lymphocytes can secrete BDNF and express its specific receptor tyrosine kinase B (TrkB). Our aim is to detect the serum BDNF level and the expression of TrkB on peripheral blood T cells in patients with dermatomyositis (DM) and their contribution to the disease pathogenesis. Methods: Twenty-six patients with DM and 30 age- and sex-matched healthy controls were enrolled. The serum BDNF level was measured by enzyme-linked immunosorbent assay (ELISA). Flow cytometry was used to measure the percentage of TrkB expression on the surface of CD3+CD4+ or CD3+CD8+T cells. Erythrocyte sedimentation rate (ESR), C-reactive protein(CRP), blood lymphocyte count, platelet count, fibrinogen, D-dimer(D-D), IgG, IgM, IgA and T cell subsets were acquired from the standard laboratory procedure. Results: Compared to the controls, the serum BDNF level of patients with DM was significantly decreased (16012.8±6012.5 pg/ml vs. 33116.5±7146.5 pg/ml, p<0.001). In addition, the serum BDNF level was significantly lower in the DM patients with interstitial lung disease (ILD) than in those without ILD (14586.6±5120.5 pg/ml vs. 20455.1±6484.5 pg/ml, p=0.028). Compared to the controls, the percentage of TrkB expression on CD3+CD4+ and CD3+CD8+ T cells was increased significantly (1.85%±1.81% vs. 0.65%±0.36%, p=0.008; 6.8%±5.27% vs. 3.0%±2.74%, p=0.007, respectively). There was no significant difference in the expression of TrkB on CD3+CD4+ or CD3+CD8+ T cells between DM patients with and without ILD. Conclusion: The serum BDNF level and TrkB expression on T cells may reflect the disease activity of DM and could be used as serological markers of DM. Especially, a serious decline in serum BDNF level may imply a pulmonary involvement of DM.
Examining Market Orientation and its Impact on New-Product Success in Pakistan

The implementation of the concept “Market Orientation” creates comparative advantage for the organizations to achieve the success of its products in the market (goods or services). This study effectively contributes to the growing literature on the influence of market orientation practices on organization’s new product success. The aim of study is to find out the impact of responsive market orientation, proactive market orientation, innovation orientation, market turbulence, technological turbulence, product quality, product price, supportive culture and after sale services on new product success in Pakistan. It identifies that the market orientation practices are significantly associated with new product success that include after sale services, market turbulence, and supportive culture.
Frutos do Cerrado: conhecimento e aceitação de Annona crassiflora Mart. (Araticum) e Eugenia dysenterica Mart. (Cagaita) por crianças utilizando o paladar e a visão doi: 10.12662/2317-3076jhbs.v3i4.168.p224-230.2015

Objetivo : Avaliar o conhecimento e a aceitacao dos frutos do Cerrado Annona crassiflora Mart. (araticum) e Eugenia dysenterica Mart. (cagaita), por criancas, utilizando o paladar e a visao. Metodos : O estudo foi realizado com 190 criancas com idade entre 7 anos e 9 anos e 11 meses da Escola Estadual Professor Jose Luiz de Araujo no municipio de Rio Paranaiba (MG), nos meses de marco e novembro de 2012. Para a avaliacao utilizando o paladar, as criancas foram direcionadas individualmente a uma sala onde foram vendadas, sendo os frutos oferecidos in natura. Para a avaliacao por meio da visao, os frutos foram apresentados em sua forma integra. As respostas foram analisadas utilizando o Teste Qui-Quadrado, com 5% de significância. Resultados : Com relacao a identificacao dos frutos, a porcentagem de acerto foi de apenas 1,58% (tanto paladar quanto visao) para o araticum, e de 14,39% (paladar) e 13,67% (visao) para a cagaita. O numero de criancas que relatou nunca ter experimento estes frutos anteriormente foi maior (p 0,05) quanto a apreciacao/depreciacao do araticum por ambos os sentidos, exceto para os meninos que depreciaram este fruto visualmente, ja a cagaita apresentou apreciacao superior (p<0,05) a depreciacao tanto por meio do paladar quanto da visao. Conclusao : A maioria das criancas apresentou um baixo conhecimento sobre ambos os frutos, pois nao os haviam experimentado anteriormente; no entanto, foram bem aceitos sensorialmente.
OCCURRENCE OF SLOW FLOW/NO REFLOW COMPLICATION DURING ROTATIONAL ATHERECTOMY: A REVIEW

Percutaneous coronary intervention (PCI) is most common form of revascularization of symptomatic coronary artery disease in modern age. There are increased chances of calcified coronary disease in elderly, diabetic and renal patients, so rotational atherectomy (RA) can be useful in such kind of calcified lesions. Rotational atherectomy is a technique where calcified lesions are debunked with the high speed rotating burr. Along with many other complications slow flow/no reflow is also a main complication of this procedure. In initial days these complications were reported at large thus decrease in the usage of this technique but with the improvement of technique, usage of pharmacological flush, glycoprotein and drug eluting stents reported decrease in complications and rise of this technique once again while treating calcified lesions. The objective of this study is to know the average occurrence of this complication in difference studies conducted in different settings. Relevant studies and articles were reviewed, analyzed and we came to the conclusion that the complication of slow flow/no reflow is generally low below 2.6 % when following recent treatment techniques and using pre-, intraand post-procedural pharmacological flush of heparin, nitroglycerine, vasodilator, glycoprotein IIb/IIIb and applying drug eluting stents after procedure.
PROBLEMS OF OPEN/RECREATIONAL SPACE DELIVERY AND MANAGEMENT IN ONITSHA, NIGERIA: IMPLICATIONS FOR SUSTAINABLE BEST PRACTICES

The health of a city, its economy and environment is improved by a properly designed and implemented master plan incorporating green areas. These open spaces and recreation areas have improved health status, maintained low stress level, decreased pollution and generally enhanced the quality of life. Human induced problems have sabotaged the recreational resources resulting in its abuse, losses and change of use. Hence, this paper investigated the problems of open/recreational space delivery and management in Onitsha with a view of proffering sustainable best practices. A survey design was employed in the study and four hundred (400) copies of designed questionnaire were distributed to randomly in selected respondents in the city to gather data. Analyses were made using descriptive statistics and one way analysis of Variance to test the hypotheses. Findings from the study showed that the drawbacks in Onitsha include inadequate number of available open spaces vis-à-vis rate of urbanization, natural population growth; poor spatial planning and land development control mechanism, lack of coherent approach to management; poor site planning and building designs. The study then recommended (i) Formulation of effective policy for recreation development in the State; (ii) Involvement of the public, private and popular sectors in the development of open spaces and recreation on public-private partnership (PPP) arrangement and (iii) promoting recreational tendencies among the youth, the adult and the aged, this will help open recreational space development and management to be highly efficient.
Impacts of Omega- 3 Fatty Acids on the Age Related Changes in the Submandibular Salivary Glands of Albino Old Rats

Objective: The present study has been designed to evaluate the histological effects of the daily consumption of omega-3 on submandibular salivary gland of old rats. Material & methods: Forty old white male rats (12-15 month age old), weighing 300 to 350gs, were used in this study. The rats were divided into two groups (20 rats/each). Control group where rats did not receive any dietary supplement. Experimental group where rats received omega-3 (60 mg/Kg) twice daily for three months through intragastric intubation. All rats were sacrificed after three months. Soft tissue specimens were obtained from submandibular salivary gland of the rats in all the studied groups. The sections were examined histologically and ultra-structurally. Results: Histopathological changes observed in control group included; distortion and decrease in the overall size of the acini and granular convoluted tubules increase in the amount of fatty tissue, fibrous tissue and inflammatory cell infiltration. In experimental group, the acini and ducts appeared nearly normal and there was marked decrease in the inflammatory cell infiltration. Electron microscopic examination of the control group revealed cytoplasmic vacuolization in acini and ducts, degenerated organelles and pyknotic nuclei. In experimental group, the acini and ducts appeared nearly normal in size, shape and structure. Conclusion: Omega-3 showed significant improvement in many age related changes of submandibular salivary gland. [Aml Aljayer, Dalia El-Baz and Maha Bashir. Impacts of Omega3 Fatty Acids on the Age Related Changes in the Submandibular Salivary Glands of Albino Old Rats. Nat Sci 2015;13(6):22-28]. (ISSN: 1545-0740). http://www.sciencepub. net/nature. 3
Role of Closed intramedullary Titanium Elastic Nailing in Fracture Shaft Femur in Children

Introduction: Fracture shaft femur is a common injury in children. The best treatment for children between 5 to 14 years of age is still debatable. The ideal device for the treatment of most displaced femoral fractures in children would be a simple, loadsharing internal splint that allows mobilization and maintenance of alignment and extremity length until bridging callus forms. Titanium elastic nails offer these features. Aim and Objectives: To assess the functional and radiological outcome of closed reduction and internal fixation of fractures of shaft femur in children aged 5-14 years with TENS. Materials and Methods: 30 patients were treated from November 2014 to July 2016 between age group of 5-14 years by retrograde TEN fixation. Patients were mobilized without weight bearing on the 7th day post operatively. Partial weight bearing was started at 6 weeks and full weight bearing at 12 weeks depending on the fracture configuration, callus response and associated injuries. Follow up was done at 6 weeks, 12 weeks and 24 weeks. Results: Average radiological union was seen in 12.8 weeks. Maximum patients achieved full range of hip and knee movements. Only two had knee stiffness. Based on Flynn‘s criteria 70% excellent and 30% good results were recorded. Conclusion: Titanium Elastic Nailing system for the treatment of paediatric shaft femur fractures in the age group of 5-14 years is an effective method, as it avoids any growth disturbance by preserving the epiphyseal growth plate, and avoids bone damage or weakening through the elasticity of the construct.
Effect of lipid peroxidation and related parameters on the storability of soybean (Glycine max) seeds

On the basis of reported storability and seed germination thirteen soybean [Glycine max (L.) Merill] genotypes (grouped as six “good storers” and seven “poor storers”) were selected to understand the relationship between lipid peroxidation, antioxidant activity and seed storability. Good storers possessed significantly high activity (p<0.05) of LOX-1 and lower activity of LOX-2 as compared to poor storers. Significant increase ((p<0.05) in HPL activity was observed in all poor storer genotypes and correlated with higher accumulation of lipid peroxides, total MDA and carbonyl content. Further our results indicated that, the good storers possessed high antioxidant activities when analyzed through DPPH and CUPRAC method than the poor storers, however the activity of antioxidants enzymes viz., SOD and catalase remained unchanged in both the good and poor storers with an exception of a good storer genotype M1090. Although no significant difference in the antioxidant compounds like tocopherols and isoflavones were found between the good and poor storers, an increased ascorbic acid content was however observed in the good storers (8.5 mg/100g to 14.74 mg/100g) as compared to the poor storers (4.82mg/100g to 6.84 mg/100g). Thus our study reflected the possible role of ascorbic acid, LOX-1, LOX-2 and HPL enzymes as potential indicators to determine the storability of soybean seeds and also can be used as the parameters to improve their nutritional quality of the soybean seeds.
Effect of Icon and Bond Type on Shear Bond Strength: An In vitro Study

Aim: To investigate the differences in SBS of orthodontic brackets after applying a caries resin infiltrant and its relationship to the bond type used. Materials and methods: A total of 48 extracted upper premolar were divided to four groups, and the force required for debonding of brackets was recorded. Residual adhesive material was examined by light microscopy. Statistical analysis was performed included t-test and Chi-square test. Result: The highest bond strength (22.543 MPa) was get by use the caries infiltrant with self-etching bond. More residual adhesive was observed on infiltrated enamel surfaces. Conclusion: Acceptable bond strengths were obtained with Icon application as measured in vitro, producing the highest strength of all tested sample when compared with the other adhesive system without Icon.
Incidence of extended-spectrum beta-lactamases in uropathogenic Escherichia coli

In the present study, a total of 259E.coli isolates were recovered from patients suffering from urinary tract infections. Resistance to ceftazidime were screened by using agar dilution technique (breakpoint method) which revealed that 132 of the isolates were ceftazidime resistant. Susceptibility testing of these E.coli isolates to other 16 beta-lactams by disc diffusion technique reveled that 100% of isolates were resistant to pipracillin (PRL), penicillin G (P). and cefazolin (CZ). In contrast, only 3(2.27%) isolates were resistant to imipenem. On the other hand, the resistance to other drugs was ranged from 12.12% to 84.09%. MICs for 3 and 4 generation cephalosporins (Ceftazidime, cefotaxime, ceftriaxone and cefipime) were determined by agar dilution technique, it was found that MICs of ceftazidime ranged from 16to 1024(μg/ml), cefotaxime ranged from 1 to 1024 (μg/ml), ceftriaxone ranged from 1 to 1024 (μg/ml) and cefipime ranged from 2 to 128 (μg/ml). A total of 106(80.30%), 72(54.54%), 82(62.12%) and 48(36.36%) of tested isolates had high level of resistance (≥64 μg/ml), (≥128 μg/ml), (≥128 μg/ml) and (≥64 μg/ml) to ceftazidime of, cefotaxime, ceftriaxone and cefepime respectively. β-lactamase (s) production was investigated by iodometric overlay test, it was found that 110 (83.3%) of tested isolates were β-lactamase (s) producers. This indicated that other mechanisms were involved in the resistance to the tested β-lactams among the remaining 22 (16.6%) isolates. ESBLs activitywas observed phenotypically in 79 out of 110 (71.81%) by using double disc synergy test and combined disc method. The data obtained from multiplex PCR showed that only 22 out of phenotypically ESBL positive isolates harbored one or two of typical ESBLs genes, which21.51% were bla TEM, 2.53% were bla SHV and 3.79% were bla CTX-M. The variation in results which in tested isolates were positive for ESBL in the phenotypic test but were negative (57 isolates) in the PCR can be explained firstly according to the types of primers used, secondly by the probable presence of another variants of ESBLs from the TEM such as TEM1, SHV such as SHV-1 and CTX-M or other ESBL families (cephalosporinases1 and/or carpabenemases) were involved which are not regarded as extended spectrum β-lactamases, presence of these enzymes lead to reduced susceptibility to third-generation cephalosporins, that phenotypically ESBL production. [Tarek El-said El-Banna, Fatma Ibrahim Sonbol, Elham T Awad and Hadeer Mohamed Abd El-Aziz. Incidence of extended-spectrum beta-lactamases in uropathogenic Escherichia coli. Nat Sci 2017;15(11):35-46]. ISSN 15450740 (print); ISSN 2375-7167 (online). http://www.sciencepub. net/nature. 5. doi:10.7537/marsnsj151117.05.
Common Congenital Neck Masses in Childhood:

Congenital neck lesions are common clinical concern in infants and children. The differential diagnosis includes congenital, inflammatory and neoplastic lesions. The physicians caring for children with congenital neck lesions (CNLs) should be aware of different presentations since these lesions are known to be complicated by infection. An orderly examination of the neck with a clear understanding of embryology and anatomy of the region will facilitate the diagnosis. Surgical intervention is cornerstone in the treatment and early referral of these patients for pediatric surgeons is recommended. The most common CNLs encountered in pediatric practice are thyroglossal duct remnants (TGDR) followed by branchial cleft anomalies (BCA) and dermoid cysts (DC) [1]. With a correct preoperative diagnosis and appropriate surgical management it is possible to prevent recurrence that is the most common complication in these lesions.
Effect of Sex Ratio on the Production and Hatchability of Broiler Breeder Flock. J. World Poult. Res. 6(1): 14-17

MSci Student of Animal science, Ghaemshahr Branch, Islamic Azad University, Ghaemshahr, Iran Animal Science Department, Ghaemshahr Branch, Islamic Azad University, Ghaemshahr, Iran DVM – Ph.D. of Poultry Sciences, Babol, Iran Department of Animal Science, College of Agriculture, Persian Gulf University, Bushehr, Iran *Corresponding author`s Email: mhaghighi9799@yahoo.com Received: 28Jan. 2016 Accepted: 03 Mar.2016 ABSTRACT Trials to compare mating ratios are important for optimizing the breeding efficiency of broilerbreeder flocks.The study provides information on the reproductive performance of broiler breeder flock (Ross308) maintained at different male: female (M: F) ratios. 381, thirty week-old broiler breeders were randomly divided into three experimental groups with three replicates each and were assigned to one of the following male: female ratio, 1M: 13.3F, 1M: 11.6F and 1M: 10.5F. The birds were randomly allotted to 9, 2m x 2m floor pens in an environmentally controlled house. Eggs were collected daily and weekly egg production/bird was calculated for each group. Hatchability and egg production were significantly affected (P<0.05) by sex ratio. 1M: 13.3Fgrouphad significantly (P<0.05) higher egg production. Hatchability of 1M: 10.5F were significantly (P<0.05) the highest followed by 1M: 11.6Fand that of 1M: 13.3F sex ratio were the lowest from week 33.Increasing the sex ratio had the effect that although average egg production/female was lower, but hatchability were improved, possibly as a result of more frequent sexual interactions of males and females.
Automatic License Plate Recognition Using OpenCV and Neural Network

Automatic license plate recognition is a Computer Vision technique which is able to recognize a license plate number. This system is useful in many field likes parking lots, private and public entrances, theft control. In this paper we designed such a system. First we capture the image from camera then load into system after that we used OpenCV library tools. Then we make the training set of different characters of different sizes. On the basis of these training set we extracted the character from images. When the license plate is detected, its digits are recognized and displayed in the GUI. In this mainly focuses on Neural Network and proprietary tools OpenCV in which ALPR systems implementing using Free Software Open Computer Vision Library including Java.
Liquid-based Cytology versus Conventional Cytology for Evaluation of Cervical Cytology in a Tertiary Care Center of Chhattisgarh

Introduction: Cervical cancer is the second most common type of cancer among women’s according to the World Health Organization. Worldwide screening programs for cervical cancer-based on the Papanicolaou smear have contributed to the decrease in incidence and mortality of cervical cancer. Objective: To compare the adequacy of smears and diagnostic difference of conventional conventional pap smear [CPS] versus liquid-based cytology (LBC). Materials and Methods: A prospective observational study was conducted in a tertiary care referral institute in 80 consecutive cervical “split samples” over a period of 1-year. Samples were taken with cervex-brush, fi rst a CPS was prepared then for LBC same brush head was suspended in preservative fl uid after detachment and processed by SurePathTM LBC. Results: There were 92.5% satisfactory smears in LBC while in CPS it was 78.8%, with statistically signifi cant difference P = 0.02. Endocervical cells were present in 57.5% of cases in CPS, while in LBC, it was present in 18.8%. Clarity of background was signifi cantly increased with LBC. Infectious organisms were better detected in LBC. Sensitivity for detection of low-grade squamous intraepithelial lesion (LSIL) (78.6%) and for high-grade squamous intraepithelial lesion (HSIL) (72.7%) was higher in LBC as compare to 71.4% and 63.6% in CPS, respectively. Specifi city was also higher in LBC 100% for both LSIL and HSIL, whereas in CPS, it was 95.8% for LSIL and 96.3% for HSIL. Conclusion: In the present study, adequacy rate for LBC signifi cantly increased, and the performance of LBC technique was better than CPS.
The Influence of Different Levels of Dietary Energy on Complement Levels `in Trypanosoma congolense infected West African Dwarf goats

Thirty six healthy WAD goats, divided into three groups A, B and C of twelve each with eight infected and four controls were placed respectively on low -2426.74kcal/kg, medium -2548.57kca/kg and high-2670.40kcal/kg levels of dietary energy but isonitrogenous feed and subsequently infected with a virulent strain of Trypanosoma congolense. The influence different levels of dietary energy on serum complement C3,total and alternative haemolytic complement parameters were evaluated up to 5 weeks post infection (p.i). The respective decline in levels of these complement system parameters were significant (P<0.05) and more pronounced in group A than B and C. There were highly significant decline (P<0.001) in complement system values of infected goats in groups A, B and C when compared with pre-infection values (C3, THC and AHC) while infected groups A, B and C were significantly different (P<0.05) to one another in values which worsened with decreasing levels of dietary energy and this indicated that dietary energy ameliorates and influences the hypo-complementaemia observed during the course of experimental trypanosomosis in goats.