Miracle-dz/UniFAR-FTUs huggingface dataset:
Effect of early Mobility and Activity interventions to reduce patients' respiratory complications associated with Congestive Heart Failure at Coronary Care Unit

Background: Congestive heart failure patients suffer from dyspnea and fatigue resulting in diminished exercise tolerance, contributing to decreased physical functioning and quality of life. The aim of this study is to evaluate effect of early mobility and activity interventions to reduce patients respiratory complications associated with Congestive Heart Failure. Design: Quasi-experimental research design. Setting: Coronary Care Unit (CCU) of El-Orman Cardiology Hospital, at Assuit University Hospitals. Sample: Seventy critically ill adult males and females' patients' divided into two equal and matched groups (35 study & 35 control). Tools: - Three tools; Tool 1: Patient assessment sheet, Tool 2: Early mobility and activity levels interventions and Tool 3: Monitoring respiratory complications sheet. Results: the patients in study group had lesser dyspnea attacks, absence of abnormal lung sound and less respiratory complications as compared with the control group patients. Conclusion: Applying early mobility and activity interventions significantly improve dyspnea; improve oxygen saturation and lesser respiratory complications associated with congestive heart failure. Recommendations: Emphasize on application of the mobility and activity for patients with cardiovascular diseases to prevent complications.
A Cognitive Approach to Diversity: Investigating the Impact of Board of Directors’ Educational and Functional Heterogeneity on Innovation Performance

Boards’ diversity has been studied mainly through the prism of ethics, which translated into a focus on characteristics such as gender and ethnicity. However, when the goal is to explain organizational outcomes, the cognitive approach seems more pertinent. Thus, rooted in a resource dependency perspective, this paper investigates the potential impact of directors’ deep level diversity (functional and educational diversity) on innovation performance based on an international sample of 97 firms for a total of 1027 directors. The findings highlight the negative effect of functional diversity (measured by diversity in the sectors of expertise), and on the opposite, the positive impact of educational diversity (measured by diversity in the fields of study) on innovation performance. This study also shows that the environment in which organizations evolve, both at the internal and external level, is crucial when it comes to innovation performance. These results are robust in that they remain consistent after addressing some potential endogeneity issues and have critical implications for both the professional and academic world.
Evaluation of the Role of the Silymarin in Modulating the Cytotoxicity of Sofosbuvir and Ribavirin as Antiviral Drugs in Mice Bone Marrow and Sperm

Sofosbuvir (S) (sovaldi) is a nucleotide analog, which is a highly active NS5B polymerase inhibitor in HCV. Sovaldi has shown high efficacy against HCV in combination with and without PEG-INF, among other medications. Ribavirin (R) is an antiviral drug which is non-selective, antihepatitis. Ribavirin has only been used in combination for treating chronic HCV infection. Silymarin (SL) is a natural antioxidant derived from the seeds and fruits of the Silybum marianum plant(Milk thistle). It's known for its impact on hepatoprotection. The goal of this study is to determine the protective effect of silymarin on the chromosome and sperm as a natural product against the side effects of sofosbuvir and ribavirin as an antiviral drug. Intraperitoneally (i.p.), male albino mice (weight 25–30 g) were injected with Sofosbuvir at a dose level of 50 mg / kg / day, ribavirin at a dose level of 20, mg / kg / day, and Silymarin at a dose level of 70 mg / kg / day injections for five consecutive days, by various means. Mice were slaughtered 24 hours later. Chromosomal abnormalities and morphology of the sperm head were studied using classical cytogenetic methods. Tests showed that Sofosbuvir and Ribavirin caused abnormalities in the structural chromosomal aberration and sperm head. Although silymarin induces reduction in all injected forms of these abnormalities.
Regio-orientation in condensation of aminopyrazoles with 1,3-difunctional reagents: synthesis of new pyrazolo[1,5-a]pyrimidines; pyrazolo[3,4-d]pyridazines and 2,4-dihydropyrano[2,3-c]pyrazoles

Pyrazolo[1,5-a ]pyrimidine derivatives were prepared by condensation of 4-phenyldiazenyl-1 H - pyrazole-3,5-diamine with enaminonitriles and with enaminones. The regioorientation of reagents was determined by ( 15 N HMBC) measurements as well as NOE difference experiments. A new one-pot synthesis of pyrazolo[3,4-d ]pyridazines involving the coupling of N 1-[4-cyano-5(3)-(cyanomethyl)-1 H -3(5)pyrazoly]acetamide with benzenediazonium chloride is reported. Synthesis of 2,4-dihydropyrano[2,3-c ]pyrazole is also reported.
RELIABILITY OF TWO IR MOTION CAPTURE SYSTEMS IN A MUSIC PERFORMANCE SETTING

This paper describes a comparative analysis of tracking quality in two infrared marker-based motion capture systems: one older but high-end (Qualisys, purchased in 2009) and the other newer and mid-range (OptiTrack, purchased in 2019). We recorded performances by a string quartet with both systems simultaneously, using the same frame rate. Our recording set-up included a combination of moving markers (affixed to musicians’ bodies) and stationary markers (affixed to music stands). Higher noise levels were observed in Qualisys recordings of stationary markers than in OptiTrack recordings, as well as a greater spatial range, though OptiTrack recordings had a higher rate of outliers (“spikes” in the signal). In moving markers, increased quantity of motion was associated with increased betweensystem error rates. Both systems showed minimal withintrial drift but a reduction in recording accuracy and precision over the duration of the experiment. Overall, our results show that the older/high-end system (Qualisys) produced slightly lower-quality recordings than the newer/midrange system (OptiTrack). We discuss how our findings may inform researchers’ interpretations of motion capture data, particularly when capturing the types of motion that are important for performing music.
Clinical and Translational Radiation Oncology Systematic review of methodology used in clinical studies evaluating the benefits of proton beam therapy

Abstract: Background Proton beam therapy (PBT) delivers high-energy radiation to target tumours while sparing surrounding normal tissues. The dosimetric advantages of PBT over traditional photon radiotherapy may be clear but the translation of this benefit into clinically meaningful reductions in toxicities and improved quality-of-life (QoL) needs to be determined. Randomised controlled trials (RCTs) are considered the gold standard for generating the highest-level evidence in medicine. The objectives of this systematic review were to provide an overview of published clinical studies evaluating the benefits of PBT, and to examine the methodology used in clinical trials with respect to study design and outcomes.
Numerical Simulation of Nocturnal Ozone Increase in Metropolitan Area of São Paulo

In large cities, pollution can not only cause deaths and illness due to exposure of people to it, but it can also reduce visibility on days of high atmospheric stability and high emission of pollutants, which can even result in vehicular accidents. Ozone is an atmospheric oxidizing gas that forms in minimal amounts naturally. People’s health can be affected by the ozone present in the air they breathe, even in low concentrations, which can worsen preexisting diseases and increase hospital admissions for respiratory diseases, especially in babies, after episodes of high pollutant levels. An increase in secondary peaks during the night of this atmospheric pollutant occurs in several parts of the world, but its formation depends on the local condition. In this sense, this work aims to study the regional atmospheric characteristics for the nocturnal ozone formation in the Metropolitan Area of São Paulo (MASP). For this, the Simple Photochemical Module (SPM) coupled with the BRAMS (Brazilian Developments of Regional Atmospheric Modeling System) will be used to simulate this condition for the urban region. The results showed that the secondary nocturnal maximum of ozone concentrations in MASP is related to vertical transport of this pollutant from higher levels of the atmosphere to the surface.
On the Variability Dimensions of Normalized Systems Applications: Experiences from Four Case Studies

—Normalized Systems Theory aims to create software systems exhibiting a proven degree of evolvability. While its theorems have been formally proven and several applications have been used in practice, no real overview of the typical types or dimensions along which such Normalized Systems software applications can evolve is present. Therefore, this paper presents several cases in which its different variability dimensions are illustrated. Based on these cases, a more general overview of four variability dimensions for Normalized Systems software applications is proposed: changes regarding the application model, expanders, craftings and technological options.
Coagulopathy is associated with multiple organ damage and prognosis of COVID-19

Mortality rate is high with COVID-19. Multiple organ damage is a common and lethal complication of the severe COVID-19 patients. Of 198 recruited participants, 65 patients (32.8 %) had coagulopathy. In this retrospective study, we analyzed the association of coagulopathy with organ dysfunction in hospitalized COVID-19 patients. The incidence of coagulopathy was associated with increased odds of acute liver injury, renal dysfunction and acute respiratory distress syndrome (ARDS) by multivariable regression. Overall mortality was 65 % for the patients with coagulopathy and 3.76 % for the patients without coagulopathy. History of hypertension, leukocytosis and elevated CRP concentrations were associated with higher odds of coagulopathy. Patients with coagulopathy had similar levels of hepatic and renal functional enzymes prior to the onset of coagulopathy as the patients without coagulopathy, suggesting that coagulopathy is an association of the progression of multi-organ dysfunction in COVID-19. Plasma IL-6 was higher in patients with coagulopathy than controls, but it's not a risk factor for organ dysfunction by logistic regression. The present study shows that coagulopathy, overt DIC and non-overt DIC, associates with organ dysfunction and higher mortality rate in COVID-19. Thus, anticoagulant therapy may prevent organ dysfunction and increase survival rate in COVID-19.
The Transmission of Monetary Policy via the Banks' Balance Sheet-Does Bank

We study the credit channel of monetary policy in South Africa between 2002 and 2019 using banks’ balance sheets. We show that there is a significant heterogeneity within the banking sector in both the loan and deposit sides of the banks’ balance sheets. In response to a contractionary monetary policy shock, big banks adjust their loan portfolio by lending to businesses and reducing lending to households whereas for small banks we find the opposite. The increase in corporate lending amid declining inventories is consistent with the hypothesis of “hedging and safeguarding the capital adequacy ratio” rather than funding business inventories. This paper highlights the importance of heterogeneity in customers, market power and business models in the banking sector, which characterises the socio-demographics dynamics in South Africa. JEL Codes: E32, E52, G21
Reverse Cohesion Effect in Second-Language Reading Comprehension: A Preliminary Study

This study investigated the effect of text cohesion on second-language reading comprehension. Twenty Japanese undergraduates read both lowand high-cohesion texts in English and performed free written recall. The results show that low-proficiency readers recall more information from high-cohesion texts than from those with low cohesion. However, highly proficient readers had the opposite tendency, indicating that the benefits of high cohesion are restricted to relatively poor readers while proficient readers are assisted by low-cohesion texts.
CHARACTERIZATION OF GMG-ITC ISOLATED FROM AERIAL PARTS OF MORINGA OLEIFERA TREE

Isothicyanate is a major bioactive compound in Moringa oleifera Lam. There are numerous literatures that report the therapeutic effects of isothiocyanates. It is for this reason that the local consumption of the plant is increasing. In the current study, we devised a rapid protocol for the extraction of ITC from the aerial parts of M. oleifera and also determined the plant part with the highest yield. The purity of the ITCs was confirmed by High Performance Liquid Chromatography analysis. Our findings revealed that the seeds contain the highest proportion of isothiocyanate. This implies that the seeds of M. oleifera could serve as invaluable feedstock for large scale extraction of the ITCs for pharmaceutical and food industries.
Medicinal prospective of Citrus limon and Citrus sinensis peels essential oil by Gas Chromatography/ Mass Spectrometry (GC/MS) compositional analysis

Citrus fruits are highly nutritious and medicinal fruits that are commonly cultivated throughout the tropics. This study was carried out to determine the bioactive compounds of the methanol peel extracts of Citrus limon and Citrus sinensis. The peels from fresh fruits of C. limon and C. sinensis were air-dried at room temperature and were pulverized into fine powder. The bioactive determinations were carried out by Gas Chromatography/Mass Spectrometry (GC/MS). The mass spectrum of the compounds found in the peels extract was matched with the National Institute of Standards and Technology (NIST) library. The results showed that four (4) and five (5) bioactive compounds were identified in C. limon and C. sinensis methanol peel extracts respectively. The C. limon peel extract contained 4-(methylsulfanyl) but-1-en-3-yne, Sulfanylphenylium, 1,3-thiazole and 3-methylidenecyclobutanecarbonitrile while C. sinensis contained Pyridine-2-carbaldehyde, 1-Methyl-1H-pyrrole-2-carbaldehyde, Glutamic acid, 2-Ethyl-5-methyl-1H-pyrrole and Pyrrolidin-2-one. The results of this study therefore unveiled that the C. limon and C. sinensis peel extracts contained variable bioactive compounds with medicinal value and could be useful raw materials for pharmaceutical industries.
Energy Fluxes and Evapotranspiration in a Rubber Agroecosystem of the Southern Thailand

Evapotranspiration (ET) plays an important role in land surface atmosphere interaction which significantly drives hydrological cycle, vegetation functioning resulting to agricultural production. In this study, observations of energy fluxes, energy partitioning, and evapotranspiration (ET) were conducted on a monoclonal stand of rubber trees (Hevea brasiliensis) plot (clone RRIM 600) in 2017. The forestry population was 17 years old and had been tapped continuously over 10 years for latex harvesting at the Rubber Estate Organization station in Na Bon district, Nakhon Si Thammarat province in Thailand. The ET rate and associated energy fluxes were determined by means of eddy covariance (EC) method and complemented by micrometeorological measurements at 25 m tall tower. Tree stands were spaced on plots of 3.0×7.0 m2 with mean canopy height of 22 m. Data were collected during January 1 to September 27, 2017. Results found that the energy balance closure of the rubber agroecosystem was approximately 78 %. Overall, the latent heat (LE) flux was the main term of energy exchange (58 - 60 %) due to its dominance across the growing season. The ratios of the latent heat (LE) and sensible heat (H) to net radiation were 0.58 and 0.24 throughout the period of study, respectively. Moreover, the daily mean of evapotranspiration (ET) was 7.16 mm.d-1 over the whole period of this study. However, a slightly higher rate of daily mean ET (7.35 mm.d-1) was indicated during the foliage period than during the leaf senescence period due to sufficient soil moisture associated with high rate of seasonal precipitation. It is concluded, that ET is an extremely sensitive variable to understand in energy flow in this ecosystems as well as a precursor for presetting condition for droughts prognosis (forecast) in a rubber ecosystem.
The Effectiveness of Emotion Coaching Parenting Program in Iranian Preschool Children With Internalizing Disorders

* Corresponding Author: Hoda Doos Ali Vand, PhD. Address: Department of Clinical Psychology, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Tel: + 98 (21) 23031548 E-mail: doosalivand.h@sbmu.ac. ir Objective: Emotion Coaching Parenting Program (ECPP) is one of the treatment programs focused on emotions and targets the way parents and children interact emotionally. Although the effectiveness of ECPP on children with internalizing disorders has been proved previously, the effects of this program have not been investigated in Iranian preschoolers with a range of internalizing disorders. Therefore, the aim of the current study was to examine the effects of ECPP when used by mothers of preschoolers with internalizing disorders.
Effects of Spatial Arrangements of Groundnut-Maize Intercrop on Growth, Yield and Proximate Composition of Groundnut

Field experiment was carried out at University of Ilorin Botanical garden between May and August 2014 to evaluate the influence of different spatial arrangements on groundnut-maize intercrop and proximate composition of groundnut seeds. Experimental layout followed completely randomized block design with three replications. The spatial arrangements investigated were 3 rows of groundnut alternated with 1 row of maize (3:1), 3 rows of groundnut alternated with 2 rows of maize (3:2), 3 rows of groundnut alternated with 3 rows of maize (3:3), sole maize and groundnut. The results indicated that growth characters such as number of leaves and leaf area were enhanced in 3G:1M and 3G:2M spatial arrangement when compared to 3G:3M and their respective sole cropping. Yield was also enhanced in the intercrop compared to their soles. The 3G:3M produced groundnut seeds with increased percentage ash, fibre and crude protein with concomitant reduction of the fat and carbohydrate when compared to other spatial arrangements and sole groundnut. The results showed that 3G:1M and 3G:2M could be considered as appropriate spatial arrangement for enhancing the growth and yield of the intercrop. The study therefore recommends that field trials be conducted outside the University Botanical Garden with the participation of extension agents and farmers to ensure the adoption of the research outcomes.
ASSESSMENT OF PATIENT SATISFACTION WITH AN E-FOLDER AND NON- E-FOLDER SYSTEMS IN TWO DISTRICT HOSPITALS IN THE EASTERN REGION OF GHANA

Background: A patient satisfied with care will translate into increased facility utilization and reflect organizational efficiency. Among several listed indicators, waiting time on a visit and staff interaction with him/her is a lasting impression that affects the out-patients’ satisfaction. The E-folder is proposed as one of the measures of improving patient satisfaction at the outpatient clinic. Objectives: This study assessed patient satisfaction at the outpatient department in an E- folder and non E-folder systems; specifically, average time spent by patients to assess full care, determine factors influencing patient waiting time, assess impact of electronic folder use on patient provider-relationship and patient’s satisfaction with care. Methods: The study used a cross-sectional design and was conducted in Kade and New Tafo government hospitals, in the Eastern Region of Ghana. Observational time and motion study with exit interview were employed to collect quantitative data, using an observational record sheet and a semi structured questionnaire as tools respectively. A sample size of 422 was used with consecutive sampling of outpatients as target group. Patients selected were followed as they moved though the various sections of the OPD and stationed research assistants in each section recorded time in and out. The pharmacy was used as final section but patients who did not use the pharmacy were exited in the last section visited. Interviews were conducted at this point Data was entered in Microsoft Office Excel 2013 version and imported into STATA SE version 15 for analysis. T-test, Pearson’s Chi-square and binary logistic regression model were used to analyst data. All significance level was set at a 0.05 alpha level and 95% confidence interval of estimates provided. Findings were compared between facilities. Results: Average total waiting time was 236.15 ± 81.28 for E-Folder facility and 365.83 ± 122.25 non-E-folder facility. The main cause of prolong waiting time was ‘Queue not followed accordingly (75.6%) and Many patients in queue (84/6%) in No- E-folder facility with percentages of 25.8% and 35.8% in E-folder facility. Both facilities rated patient provider relationship ‘Good’ with over 80%. Overall satisfaction with care was 76.5% (E- Folder) and 50.5% (Non -E-Folder). Conclusion: Total waiting time exceeds recommended 90-120 minutes. Time is the most significant indicator of patient satisfaction. The Type of record system has significant influence on patient satisfaction. Recommendation: The E-folder system coupled with a multi-unit and managerial effort, are recommended as means of improving patient satisfaction.
THE IMPACT OF ECONOMIC POLICY UNCERTAINTY CAUSED BY THE BREXIT REFERENDUM ON AGGREGATE AND SECTORAL-LEVEL FDI INTO THE UK

This paper performs a time-series and a fixed-effects panel data analysis to investigate the effect of economic policy uncertainty, caused by the Brexit referendum, on aggregate and sectoral-level FDI into the UK for the period 20102019. In general, on average, the number of M&A projects decreases by 1,041% after Brexit. A 1% increase of EPU will cause the number of M&A projects to decrease by 0,173% before Brexit; however, after the referendum, an 1% increase of EPU will cause the number of M&A projects to increase by 0,049%. A similar effect is observed on the sectoral model: On average, there are 12,45 less M&A projects per sector after Brexit than before. However, after Brexit, a 1% rise in EPU will result in a rise of 2,697 M&A projects. The positive moderating effect of Brexit can be attributed to firms’ conceptions. The service sector consistently has a higher number of M&A disinvestment compared to the primary and manufacturing sectors. When EPU increases by 1%, the service sector has an average reduction of 0,639 M&A projects more than non-service sector. Banks and Insurance sector is the most affected by the referendum due to potential changes in the regulations regarding the EU market.