Miracle-dz/UniFAR-FTUs huggingface dataset:
Traditional Knowledge Evolution over Half of a Century: Local Herbal Resources and Their Changes in the Upper Susa Valley of Northwest Italy

Susa Valley, located in the Italian Western Alps, has served as a meeting point for cultural, spiritual, and commercial exchange for a long period of history. The valley’s role as one of the main connecting routes between south and southwestern Europe resulted in its acquisition of a rich traditional ecological knowledge. However, like other Italian mountainous valleys, this valley has suffered from abandonment and depopulation in the past 50 years. Our study aims to investigate the current ethnobotanical medicinal knowledge in the valley and to compare our findings with a study conducted over 50 years ago in the same area. In 2018, we conducted 30 in-depth semi-structured interviews on medicinal plants and food-medicines used in the Susa Valley. We documented 36 species, of which 21 species were used for medical purposes and 15 species were used as food-medicine. The comparison with the previous study on medicinal herbs conducted in 1970 in the valley demonstrated a significant decrease in both the knowledge and use of medicinal plants, which could be attributed to socioeconomic, cultural, and possibly environmental changes that occurred in the past half-century. Our study highlights several promising species for future use as nutraceuticals, food, and medicinal products, such as Taraxacum officinale, Urtica dioica, and Artemisia genipi.
Knowledge and awareness toward anterior cruciate ligament (ACL) injury among population of Aseer region, Saudi Arabia

Purpose: The aim of this article is to determine the knowledge and awareness of population toward anterior cruciate ligament (ACL) injury in Aseer region, and to determine the extent of knowledge about what does a person with ACL injury suffer from, and thus investigate the main sources of information that public obtained their medical information about sport injury from. Materials and Methods: This is a cross-sectional study based on a questionnaire distributed to the participants either in malls, campuses, or campaigns and filled by them in Aseer region. A sample of 576 participants was successfully interviewed. Convenience sampling method was used. Results: Nearly all of the participants considered this injury as a multi-factorial incident resulting from a combination of any of the following risk factors: sports, high body weight, heavy housework, and car accidents. Regarding mechanisms responsible about occurrence of ACL injuries during playing sports, the majority (60.8%) proposed a combination of two or more incorrect technical movements: lack of self-protection awareness, insufficient preparation, and overload of exercise. Regarding the participant's information about methods that could decrease pain of ACL injury, about three quarters of all participants (72.2%) stated that resting could alleviate pain. Moreover, most of individuals with previous ACL injury confirmed this. In addition, those with pervious ACL injury supported the role of ice significantly more than the remainder (53.6% vs. 48.1%). Prescription pain medications were selected by 47.3% of all participants. In all, 53.8% of all participants considered Internet as a main source of information about ACL injury. Conclusion: Findings indicated reasonable awareness of the general population in Aseer region about the seriousness of ACL injury, but there was a lack of information about risk factors other than sports, that is, dangerous actions that increase incidence of ACL injuries and their characteristic symptoms.
Characteristics of the complete chloroplast genome of Saxifragaceae species Bergenia purpurascens (Hook. f. et Thoms.) Engl

Abstract Bergenia purpurascens (Hook. f. et Thoms.) Engl. is one species of traditional Chinese medicinal plant. This is the first publication of its complete chloroplast (cp) genome. The whole cp genome has 157,246 base pairs in length with 132 annotated genes, of which were 87 protein-coding genes, 37 tRNAs, and 8 rRNAs. According to the phylogenetic study, B. purpurascens and Bergenia scopulosa T. P. Wang. 1974 had a sister relationship. This genomic data and conclusions from B. purpurascens phylogenetic research will provide useful information and throw light on more in-depth investigations of the systematics and evolutionary patterns of Saxifragaceae.
Toward Understanding Asset Flows in Crypto Money Laundering Through the Lenses of Ethereum Heists

With the overall momentum of the blockchain industry, financial crimes related to blockchain crypto-assets are becoming increasingly prevalent. After committing a crime, the main goal of cybercriminals is to obfuscate the source of the illicit funds in order to convert them into cash and get away with it. Many studies have analyzed money laundering (ML) in the field of the traditional financial sector. However, in terms of the emerging blockchain crypto-asset ecosystem, there is currently only one public anti-money laundering (AML) dataset for Bitcoin– the Elliptic dataset, whose binary labels (licit vs. illicit transactions) cannot cover the ML behaviors in the evergrowing crypto-asset market. To fill this gap, in this paper, we propose a framework named XBlockFlow which identifies ML addresses starting from Ethereum heist incidents and obtains the first detailed Ethereum ML dataset named $\textit {EthereumHeist}$ , and then conducts a comprehensive feature and evolution analysis on the $\textit {EthereumHeist}$ dataset according to the three main phases of ML. We first search for the source cybercriminal accounts including exchange hackers, DeFi exploiters, and scammers. Then, employing the idea of taint analysis, we track the diverse downstream transactions and addresses layer by layer. At the end of tracking, we identify and categorize service providers, and go a step further to investigate advanced ML methods that do not exist in the Bitcoin scenario, e.g. token swap and counterfeit token creation. Based on the ML identification results, we obtain many interesting findings about crypto-asset money laundering, observing the escalating money laundering methods such as creating counterfeit tokens and masquerading as speculators.
A Novel Risk Score Model for the Differential Diagnosis of Type 2 Diabetic Nephropathy: A Multicenter Study

Introduction DN is a common complication of diabetes. However, diabetes combined with renal injury may involve DN or NDKD, with different treatment schemes. The purpose of our study was to determine the independent risk factors of DN and establish a risk score model to help differentiate DN and NDKD, providing a reference for clinical treatment. Methods A total of 678 T2D patients who had undergone renal biopsy in four affiliated hospitals of Peking University were consecutively enrolled. Patients were assigned to the DN group and NDKD group according to histopathological results. Seventy percent of patients from PKUFH were randomly assigned to the training group, and the remaining 30% were assigned to the internal validation group. Patients from the other three centers were assigned to the external validation group. We used univariate and multivariate logistic regression analyses to identify independent risk factors of DN in the training group and conducted multivariate logistic regression analysis with these independent risk factors in the training group to find regression coefficients “β” to establish a risk score model. Finally, we conducted internal and external validation of the model with ROC curves. Results Diabetic retinopathy, diabetes duration ≥ 5 years, eGFR < 30 ml/min/1.73 m2, 24 h UTP ≥ 3 g, and no hematuria were independent risk factors (P < 0.05), and each factor scored 2, 1, 1, 1, and 1. We assigned the patients to a low-risk group (0-1 points), a medium-risk group (2-3 points), and a high-risk group (4-6 points), representing unlikely DN, possibly DN, and a high probability of DN, respectively. The AUCs were 0.860, 0.924, and 0.855 for the training, internal validation, and external validation groups, respectively. Conclusion The risk score model could help differentiate DN and NDKD in a noninvasive manner, reduce the number of renal biopsies, and provide a reference for clinical treatment.
Right Competencies for the right ICT Jobs – case study of the Croatian Labor Market

The development of information and communication technologies (ICT) has led to the significant changes in many areas of human lives. One of the aspects becoming much more challenging is the education of ICT professionals. Latest statistics show that the labor market demand for ICT practitioners exceeds the number of higher education graduates in the field of ICT. This paper provides a brief overview of the past and current situation on the labor market regarding the demand for ICT professionals, as well as forecasts by 2020. Paper also provides a research of demanded competencies in ICT jobs advertisements, and their comparison with competencies defined within the e-Competence framework 3.0 and generic competencies defined by Tuning project.
Claudins in genitourinary tract neoplasms: mechanisms, prognosis, and therapeutic prospects

Genitourinary (GU) cancers are among the most prevalent neoplasms in the world, with bladder cancers constituting 3% of global cancer diagnoses. However, several pathogenetic mechanisms remain controversial and unclear. Claudins, for example, have been shown to play a significant role in several cancers of the human body. Their role in GU cancers has not been extensively studied. Aberrant expression of claudins −1, −2, −3, −4, −7, and −11 has been expressed in urothelial cell carcinomas. In prostate cancers, altered levels of claudins −1, −2, −3, −4, and −5 have been reported. Furthermore, the levels of claudins −1, −2, −3, −4, −6, −7, −8, and −10 have been studied in renal cell carcinomas. Specifically, claudins −7 and −8 have proven especially useful in differentiating between chromophobe renal cell carcinomas and oncocytomas. Several of these claudins also correlate with clinicopathologic parameters and prognosis in GU cancers. Although mechanisms underpinning aberrant expression of claudins in GU cancers are unclear, epigenetic changes, tumor necrosis factor-ɑ, and the p63 protein have been implicated. Claudins also provide therapeutic value through tailored immunotherapy via molecular subtyping and providing therapeutic targets, which have shown positive outcomes in preclinical studies. In this review, we aim to summarize the literature describing aberrant expression of claudins in urothelial, prostatic, and renal cell carcinomas. Then, we describe the mechanisms underlying these changes and the therapeutic value of claudins. Understanding the scope of claudins in GU cancers paves the way for several diagnostic, prognostic, and therapeutic innovations.
DNase improves the efficacy of antimicrobial photodynamic therapy in the treatment of candidiasis induced with Candida albicans

The study evaluated the association of DNase I enzyme with antimicrobial photodynamic therapy (aPDT) in the treatment of oral candidiasis in mice infected with fluconazole-susceptible (CaS) and -resistant (CaR) Candida albicans strains. Mice were inoculated with C. albicans, and after the infection had been established, the tongues were exposed to DNase for 5 min, followed by photosensitizer [Photodithazine®(PDZ)] and light (LED), either singly or combined. The treatments were performed for 5 consecutive days. Treatment efficacy was evaluated by assessing the tongues via fungal viable population, clinical evaluation, histopathological and fluorescence microscopy methods immediately after finishing treatments, and 7 days of follow-up. The combination of DNase with PDZ-aPDT reduced the fungal viability in mice tongues immediately after the treatments by around 4.26 and 2.89 log10 for CaS and CaR, respectively (versus animals only inoculated). In the fluorescence microscopy, the polysaccharides produced by C. albicans and fungal cells were less labeled in animals treated with the combination of DNase with PDZ-aPDT, similar to the healthy animals. After 7 days of the treatment, DNase associated with PDZ-aPDT maintained a lower count, but not as pronounced as immediately after the intervention. For both strains, mice treated with the combination of DNase with PDZ-aPDT showed remission of oral lesions and mild inflammatory infiltrate in both periods assessed, while animals treated only with PDZ-aPDT presented partial remission of oral lesions. DNase I enzyme improved the efficacy of photodynamic treatment.
Exploring in-service preschool teachers’ acceptance of mobile learning in science teaching practice

In the sphere of preschool and elementary education, new interactive technologies built on intelligent mobile devices and auxiliary applications have drawn increasing attention. Based on the UTAUT2 (The expanding of the unified theory of acceptance and use of technology) theoretical model, the purpose of this study is to understand the situation of pre-school preschool teachers’ willingness to use mobile learning. This study conducted a survey on 329 in-service preschool teachers in 9 cities in Fujian Province, China, and conducted data analysis through statistical analysis software SPSS (Statistical Product and Service Solutions) 22.0 and AMOS (Analyze of Moment Structures) 22.0, verifying the UTAUT2 model in Effectiveness in understanding in-service early childhood teachers’ intention to move to learn. The results of structural equation modeling show that the proposed model has acceptable fitting data. The results of the study show that in-service preschool teachers have the willingness to actively accept mobile learning. Among many influencing factors, performance expectancy, effort expectancy, social influence, facilitating conditions, learning value, habit have significantly impact on behavioral intention to accept mobile learning. In addition, hedonic motivation did not support to affect behavioral intention and habit to affect use behavior. The study has important implications for researchers, educators, policy makers and mobile learning app designers.
Multi-model Climate Change Projections for Belu River Basin, Myanmarunder Representative Concentration Pathways

Climate change impacts and adaptation related studies in Myanmar are scanty. Therefore this study aims to project future climate scenarios considering two key meteorological parameters-temperature and precipitation -in Belu River Basin in Myanmar. Multi-GCMs approach with ten different GCMs on 10th to 90th percentile uncertainty range is studied using time series data of nine meteorological stations. Quantile mapping technique is used to correct the bias in raw GCM data. Bias corrected GCM ensembles are analysed for a wide range of climate scenarios to get the complete picture of climate change pattern for 21st century. All ten GCM ensembles (four RCP scenarios) indicate that the monsoon to get wetter as well as delayed. August will witness highest amount of rainfall. More rain concentrating over shorter time span suggests likely increase in extreme precipitation events. Only a slight increase is expected on the overall annual precipitation (-1.78~+ 9.14%, range of values from four scenarios). Minimum temperature is found to increase almost twice (+0.64~+5.27C) as compared to maximum temperature (+0.56~+2.82°C) under different scenarios. Summer is the hardest hit season with May and April the most affected months for maximum and minimum temperatures respectively. These results are very useful for further research on assessment of vulnerability and adaptation on water resources and water use sectors in Belu River Basin in Myanmar.
Progress in research on and classification of surgical methods of arthroscopic reconstruction of the ACL and ALL using a shared tendon graft through the femoral tunnel

Anterior cruciate ligament (ACL) tear is a common clinical injury, and ACL reconstruction has reached a very mature stage. However, with the accumulation of cases, scholars have found that isolated ACL reconstruction may not completely solve the problem of knee rotational stability. With the increase in our understanding of knee joint structure, ACL combined with anterolateral ligament (ALL) reconstruction has become accepted by most scholars, and this operation has also achieved good clinical results. At present, there is no unified surgical method for ACL combined with ALL reconstruction. There are differences in bone tunnel location, reconstruction methods, and graft selection. Compared with the independent reconstruction of the ACL and ALL during the operation, shared tendon graft reconstruction of the ACL and ALL has the advantages of preserving tendon and avoiding tunnel convergence. So far, there is no relevant literature summarizing the reconstruction of the ACL and ALL with a shared tendon graft. This paper reviews the anatomic study of the ALL, the study of isometric points, surgical indications, and surgical methods and their classification for shared tendon graft reconstruction of the ACL and ALL.
Application of Near-Infrared Reflectance Spectroscopy for Predicting Chemical Composition of Feces in Holstein Dairy Cows and Calves

Simple Summary Digestibility is a crucial factor for assessing feed costs for dairy cattle. Rapid analysis of fecal composition is necessary to obtain accurate data on digestive efficiency. Traditional wet chemical analysis methods are time-consuming; therefore, the potential of near-infrared reflectance spectroscopy technique was explored for assessing fecal chemical components in dairy cattle. The technique has been widely used to predict the nutritional contents of raw materials and complete feeds. In the present study, near-infrared reflectance spectroscopy could successfully predict the chemical composition of dairy cattle feces, thereby reducing analysis time and workload. Abstract Traditional methods for determining the chemical composition of cattle feces are uneconomical. In contrast, near-infrared reflectance spectroscopy (NIRS) has emerged as a successful technique for assessing chemical compositions. Therefore, in this study, the feasibility of NIRS in terms of predicting fecal chemical composition was explored. Cattle fecal samples were subjected to chemical analysis using conventional wet chemistry techniques and a NIRS spectrometer. The resulting fecal spectra were used to construct predictive equations to estimate the chemical composition of the feces in both cows and calves. The coefficients of determination for calibration (RSQ) were employed to evaluate the calibration of the predictive equations. Calibration results for cows (dry matter [DM], RSQ = 0.98; crude protein [CP], RSQ = 0.93; ether extract [EE], RSQ = 0.91; neutral detergent fiber [NDF], RSQ = 0.82; acid detergent fiber [ADF], RSQ = 0.89; ash, RSQ = 0.84) and calves (DM, RSQ = 0.92; CP, RSQ = 0.89; EE, RSQ = 0.77; NDF, RSQ = 0.76; ADF, RSQ = 0.92; ash, RSQ = 0.97) demonstrated that NIRS is a cost-effective and efficient alternative for assessing the chemical composition of dairy cattle feces. This provides a new method for rapidly predicting fecal chemical content in cows and calves.
THE ANALYSIS OF DIET AND PHYSICAL ACTIVITY PATTERNS IN NURSING MANAGEMENT FOR CORONARY HEART DISEASE PATIENTS

Cardiovascular disease caused by impaired function of the heart and blood vessels, such as coronary heart disease, heart failure, hypertension and stroke caused by improper diet and physical activity patterns. The purpose of this study was to describe the pattern of eating and physical activity patterns in coronary heart disease patients with a history of hypertension. The research method used is descriptive analysis using a cross-sectional approach. The sampling technique used was accidental sampling with a total sample of 130 respondents. The instruments used are Food Frequency Questioinnaire (FFQ) for diet and Global Physical Activity Questioinnaire (GPAQ) for physical activity patterns. The results showed that the picture of the eating pattern in coronary heart disease patients with a history of hypertension was poor diet (53.1%), the description of the pattern of physical activity was the most in the light category (50.0%). Conclusion: In this study, it was found that diet and physical activity patterns in coronary heart disease patients with a history of hypertension were found to have poor diet and light physical activity patterns.Keywords: coronary heart disease, eating pattern, hypertension, physical activity patterns
The Efficacy of Dietary Interventions in Patients with Gastroesophageal Reflux Disease: A Systematic Review and Meta-Analysis of Intervention Studies

Background: International guidelines recommend dietary interventions as one of the most important treatments for patients with gastroesophageal reflux disease (GERD). Evidence to confirm the efficacy of these treatment modalities is lacking. The present study aims to evaluate the efficacy of dietary interventions on GERD-related outcomes evaluated in intervention studies on GERD patients. Methods: A systematic review and meta-analysis was performed according to PRISMA. The PubMed/MEDLINE, Web of Sciences, and Scopus databases were utilized for the literature search. Two independent researchers searched for relevant publications published up until June 2023. Intervention studies evaluating the efficacy of dietary interventions in patients with GERD were included. Results: A total of 577 articles were identified during the initial literature search. After reviewing, 21 studies with 16 different types of dietary interventions were included in the analysis. The interventions were divided into low-carbohydrate diets (3 studies), high-fat diets (2 studies), speed of eating studies (3 studies), low-FODMAP diets (2 studies), and other interventions (12 studies). A meta-analysis could be performed for low-carbohydrate diets and speed of eating interventions. Low-carbohydrate diets resulted in a significant reduction in esophageal acid exposure time (mean difference = −2.834%, 95% confidence interval (CI): −4.554 to −1.114), while a slow speed of eating did not lead to a lower percentage of reflux events compared to fast eating (risk ratio = 1.044, 95% CI: 0.543–2.004). Most other interventions showed positive effects in only a single study. Conclusion: Low-carbohydrate diets showed a significant improvement in GERD-related outcomes, while a slow eating speed did not result in a reduction in reflux events. The overall evidence regarding dietary interventions in GERD remains scarce. High-quality, long-term RCTs are still required to confirm the effects of dietary interventions in GERD patients.
Diurnal atmosphere‐ocean signals in Earth's rotation rate and a possible modulation through ENSO

Space geodetic determinations of a 6 μs length‐of‐day (LOD) anomaly at the diurnal S1 frequency are reconciled with excitation estimates from geophysical fluid models. Preference is given to a hybrid excitation scheme that combines atmospheric torques with oceanic angular momentum (OAM) terms from hydrodynamic forward modeling. A joint inversion of all data sets yields an LOD in‐phase and quadrature estimate of (5.91, −0.22) μs, matching space geodetic S1 terms well within their formal uncertainties. Non‐harmonic LOD excitations, while less than 30% of the time‐averaged rotation rate contribution, are conclusively linked to El Niño–Southern Oscillation (ENSO) as the main perturbation of diurnal cycle characteristics in the troposphere. ENSO modulations of particular relevance are those in OAM, associated with the barotropic ocean response to regional modifications in the diurnal atmospheric pressure wave. The study thus highlights previously unexplored aspects of non‐tidal mass‐field variability in the Earth system.