Miracle-dz/UniFAR-FTUs huggingface dataset:
A Physical Rehabilitation Approach for Parkinson’s Disease: A Systematic Literature Review

Parkinson's disease (PD) is one of the most common neurological ailments. With diverse motor affectations (postural instability, resting tremor, bradykinesia, and rigidity), people with Parkinson's disease (PwP) have a broad spectrum of non-motor symptoms. These include autonomic function changes, cognitive deterioration, neuropsychiatric difficulties, and sleep interruptions. Psychological disturbances, such as anxiety and sadness, are common among PwP. This discomfort is often accompanied by a decrease in general functioning, both at work and in social contacts. Furthermore, people who are experiencing psychological distress have a quick decrease in both physical and cognitive capacities. Furthermore, Pwp who also suffer from anxiety and depression are more likely to acquire dementia. It is worth noting that studies have shown good outcomes in the treatment of physical disabilities in PWP and the various therapeutics available for each affected body part, such as in the legs when they have walking problems, resting tremor in their hands, or micrography, which is a common symptom in these patients. The medical research databases PubMed/Medline, Google Scholar, and the Cochrane Library were used to look for relevant materials. Upon meticulous scrutiny, a thorough investigation was conducted on the papers at hand. A total of 10 publications were meticulously selected based on stringent qualifying criteria. The present investigation examines various perspectives regarding the physical rehabilitation of individuals diagnosed with PD. The majority of therapeutic interventions employed revolve around cutting-edge technologies, such as virtual reality (VR), combined with exercise regimens. These interventions have demonstrated notable statistical significance in terms of enhancing various physical aspects, including endurance, performance, gait capacity, perception, and overall independence in daily life activities. One of the gathered studies makes use of the therapeutic benefits of yoga to help PwP deal with their anxiety and improve their mental health. Based on the aforementioned information, further investigation is required to ascertain the optimal approach for physical rehabilitation management and develop diverse strategies aimed at assisting individuals with PD in attaining physical autonomy.
The Next Crisis?: Direct and Equity Investment in Developing Countries

* 1. Introduction * 2. Capital Flows, Development and Debt Crises * 3. The Nature of Direct and Equity Investment and the Positive View * 4. Recent Trends in Development Finance * 5. Ignorance is Bliss? Data on the Stocks of Direct and Equity Investment * 6. Ignorance is Bliss II: Data on Capital Flows, Profits and FDI-Related Trade * 7. The Foreign Exchange Dimension: General Principles * 8. Foreign Exchange Effects of Direct and Equity Investment on the Host Country * 9. Other Effects at the National Level * 10. The Global Dimension: Competition for Direct Investment and Export Markets * 11. Net Transfers and the Build-Up of Investment Stocks * 12. Surges and Cycles * 13. Was That It? Direct Investment and Current Account Deficits in the Mexican and Asian Financial Crises * 14. Was That It II: Capital Flows of FDI and Equity Investment in the Mexican and Asian Crises * 15. Conclusions and Policy Implications * Annex I: Data Discrepancies and the Balance of Payments Effects of Direct Investment in Thailand * Annex II: Balance of Payments Effects of Direct Investment in Malaysia: Data Limitations and Sensitivity to Assumptions
Effect of the Adhesive Strategy on Clinical Performance and Marginal Integrity of a Universal Adhesive in Non-Carious Cervical Lesions in a Randomized 36-Month Study

The effectiveness of a universal adhesive applied in three application modes for the preparation of Class V composite restorations was evaluated both clinically and by quantitative marginal analysis (QMA) over 36 months. In 50 patients, three (n = 21) or four (n = 29) non-carious cervical lesions (NCCL) were restored with Venus® Diamond Flow (Kulzer GmbH, Hanau, Germany). The adhesive iBond® Universal (iBU, Kulzer, Germany) was used in self-etch (SE), etch-and-rinse (ER), or selective-enamel-etch mode (SEE). The etch-and-rinse adhesive OptiBondTM FL served as a control (OFL, Kerr GmbH, Herzogenrath, Germany). The restorations were clinically assessed (FDI criteria) at 14 days (BL), 6, 12, 24, and 36 months. Additionally, QMA was conducted on all restorations of 11 randomly selected patients. FDI criteria and marginal gap and perfect margin were compared between and within groups and recalls using McNemar, Wilcoxon, or Mann–Whitney U-tests (α = 0.05). Starting with 12 months, cumulative failure rates were lower in iBU-SE (0.0%, p = 0.016) and iBU-ER groups (2.1%, p = 0.07) compared to OFL (16.7%). At two years, iBU-SEE also showed fewer failures (0.0% SEE vs. 34.6% OFL, p = 0.016), as did iBU-SE compared to iBU-ER after 36 months (2.2 and 19.6%, p = 0.039). From BL, the iBU-SEE group always had the fewest marginal gaps and the highest percentage of perfect margins. From BL, iBU-SEE (0%, p = 0.008) and iBU-ER (0.2%, p = 0.027) showed significantly fewer marginal gaps compared to OFL (2.5%) and more perfect margins were found with iBU-SEE starting at 6 months (p = 0.054). The SEE and ER modes ensured the most excellent marginal quality, with differences from the control appearing earlier with QMA than clinically. In restoring NCCls, iBU showed superior clinical performance over OFL, especially in modes SE and SEE.
Comparative patterns of principal component and cluster analysis under sodicity and normal soil conditions in rice (Oryza sativa L.)

Rice is an important food crop that feeds majority of world population. The crop is sensitive to sodicity stress and the area under sodicity is gradually increasing, resulting in decline in productivity. The present investigation aimed to study the genetic diversity patterns of rice germplasm under sodicity and normal soil conditions using principal component and hierarchical cluster analysis. The germplasm was raised at two different environments and the observations were subjected to principal component and hierarchical cluster analysis. The principal component analysis identified four principal components having eigen value greater than one under sodic as well as normal soil environments. The genotypes that exhibited higher values for a particular trait were identified using the biplot as they were located closer to the trait vector. The comparison of biplots revealed that trait vectors for DFF, FLB, HGW and SPY were located at different quadrants under sodic and normal soil environments. Hierarchical cluster analysis grouped the rice genotypes into five clusters under both environments. The tolerant (TG63, TG121 and TG17) and susceptible (TG54, TG55, TG86 and TG185) genotypes were identified by comparing the clustering pattern of these genotypes under sodic and normal soil conditions. Identification of clusters with higher genetic distance (cluster I and cluster V) could be employed in plant breeding programmes to produce higher frequency of transgressive segregants and develop sodicity tolerant rice varieties.
Patient-reported outcomes of serum eye drops manufactured from Australian blood donations and packaged using Meise vials

Introduction Serum eye drops (SED) are an effective treatment for dry eye syndrome. However, autologous serum collection can have challenges. Patient-tailored (allogeneic) SED (PT-SED) can be made from healthy blood donors. Australian Red Cross Lifeblood has manufactured both autologous SED (Auto-SED) and PT-SED and, in May 2021, introduced Meise vial packaging. This study aimed to explore SED patient-reported outcomes and vial packaging satisfaction. Methods A prospective cohort study was conducted with recruitment between 1 November 2021 and 30 June 2022. Participants completed the dry eye questionnaire (DEQ5), health-related quality-of-life (SF-8™), functional assessment of chronic illness therapy-treatment satisfaction-general (FACIT-TS-G), and general wellbeing surveys. Existing patients completed these once, and new patients were surveyed at baseline, 3 months post-treatment, and 6 months post-treatment. Results Participants who completed all study requirements were 24 existing and 40 new Auto-SED and 10 existing and 8 new PT-SED patients. Auto-SED patients were younger [56.2 (±14.7) years] than PT-SED patients [71.4 (±10.0) years]. Participants used a mean of 1.8 (±1.1) SED, 5.3 (±2.9) times per day. In new patients, DEQ5 scores improved within 6 months from 14.0 (±2.9) to 10.6 (±3.4) for Auto-SED and from 12.9 (±3.7) to 11.4 (±2.8) for PT-SED. General wellbeing measures improved in the new Auto-SED from 7.0 (±1.9) to 7.8 (±1.7) but were reduced for new PT-SED from 6.7 (±2.9) to 6.1 (±2.9). Discussion SED improved dry eye symptoms in most patients, regardless of the serum source. Patients using PT-SED showed decreases in some quality-of-life measures; however, recruitment was reduced due to operational constraints, and concurrent comorbidities were not assessed. General feedback for SED and vial packaging was positive, with some improvements identified.
The Positive Impact of Digital Literacy on Science Process Skills

Students' science process skills are important to improve, one of which is by using technology so that students' digital literacy skills are also needed in using technology. The purpose of this study was to analyze the effect of digital literacy on science process skills. The type of research used is a mix method with a sequential explanatory model. The population in sthis study were students in class X MIPA at senior high school. The sampling technique used was simple random sampling and a sample of 50 students was obtained and the instruments included questionnaires, observations and teacher interviews. Quantitative data were obtained from questionnaires and observations while qualitative data were obtained from interviews. After the research is done, the data will be analyzed. Quantitative data analysis used statistical tests, namely descriptive statistics and parametric inferential statistics. Descriptive statistical analysis is presented in tabular form in the form of frequency, mean, median, max value and min value while inferential parametric analysis is in the form of a t test with prerequisite tests: normality test and linearity test. While the qualitative data uses Miles & Huberman. The research results obtained were that digital literacy had an effect on science process skills with a percentage of 93.5%.
Conserved Domains in Variable Surface Lipoproteins A-G of Mycoplasma hyorhinis May Serve as Probable Multi-Epitope Candidate Vaccine: Computational Reverse Vaccinology Approach

Simple Summary In this study, we designed a multi-epitope vaccine candidate for M. hyorhinis. This is the first study using conserved regions of seven members of Vlps and has shown an effective approach toward vaccine development. The proposed vaccine candidate is highly stable and soluble. It elicits an impressive immune response and can be regarded as a hypothetical vaccine candidate in the future. Further laboratory tests and animal inoculation are required to validate vaccine efficacy and safety to combat swine infections. Abstract Mycoplasma hyorhinis (M. hyorhinis) is responsible for infections in the swine population. Such infections are usually cured by using antimicrobials and lead to develop resistance. Until now, there has been no effective vaccine to eradicate the disease. This study used conserved domains found in seven members of the variable lipoprotein (VlpA-G) family in order to design a multi-epitope candidate vaccine (MEV) against M. hyorhinis. The immunoinformatics approach was followed to predict epitopes, and a vaccine construct consisting of an adjuvant, two B cell epitopes, two HTL epitopes, and one CTL epitope was designed. The suitability of the vaccine construct was identified by its non-allergen, non-toxic, and antigenic nature. A molecular dynamic simulation was executed to assess the stability of the TLR2 docked structure. An immune simulation showed a high immune response toward the antigen. The protein sequence was reverse-translated, and codons were optimized to gain a high expression level in E. coli. The proposed vaccine construct may be a candidate for a multi-epitope vaccine. Experimental validation is required in future to test the safety and efficacy of the hypothetical candidate vaccine.
Relationship of Momentary Volition to Occupational Experience and Life Perspective in Undergraduate Students

Our lives are comprised of moment-to-moment activities and experiences. According to the Model of Human Occupation, our occupational experiences can be affected by volition, which consists of personal causation, values, and interests. This study investigated how momentary volition could affect activity satisfaction and mind-wandering while performing occupations. This study also examined the relationship of momentary volition with overall life perspectives on life satisfaction and life balance. Undergraduate students participated in this cross-sectional study. The experience sampling method (ESM), which repeatedly collects real-time data in everyday life, was applied in this study to measure students’ momentary states such as activity, volition, activity satisfaction, and mind-wandering. After completing the ESM, participants’ life satisfaction and life balance were measured using the Satisfaction With Life Scale (SWLS) and the Life Balance Inventory (LBI), respectively. Forty-two participants and 1092 sampling data points were included in the analysis. At the event level, regression analysis was performed to identify volition elements to contribute to activity satisfaction and mind-wandering. At the personal level, correlation analysis was used to determine the relationship of momentary volition to life satisfaction and life balance. Momentary personal causation, values, and interests contributed to activity satisfaction. Mind-wandering was predicted negatively by interests but positively by personal causation. Momentary interests were positively correlated with SWLS and LBI scores. This study demonstrated that momentary volition was associated with activity satisfaction and engagement, as well as life satisfaction and balance in undergraduate students. Momentary volition, especially interests, contributed to positive occupational experiences and life perspectives. This study suggests that occupational therapy practitioners need to consider momentary interests to provide occupation-centered interventions for undergraduate students.
Rhizobium etli is able to emit nitrous oxide by connecting assimilatory nitrate reduction with nitrite respiration in the bacteroids of common bean nodules

ABSTRACT Legumes can contribute to emissions of the potent greenhouse gas nitrous oxide (N2O) directly by some rhizobia species that are able to denitrify under free-living conditions and in symbiotic association with the plant. In this study, the capacity of Phaseolus vulgaris-Rhizobium etli symbiosis to emit N2O in response to nitrate (NO3 -) has been demonstrated for the first time. We found that bacteroidal assimilatory nitrate reductase (NarB) as well as nitrite reductase (NirK) and nitric oxide reductase (cNor) denitrifying enzymes contribute to nitric oxide (NO) and N2O formation in nodules. We also show that R. etli NarK is involved in NO2 - extrusion and links NO3 - reduction by NarB in the cytoplasm with NirK and cNor denitrification activities in the periplasm. The knowledge generated in this work will be instrumental for exploring strategies and sustainable practices in agricultural soil management to increase legume crop yield and mitigate greenhouse gas emissions. HIGHLIGHTS Common bean nodules are able to produce N2O in response to nitrate. Nitrate reduction to nitrite in R. etli bacteroids catalyzed by assimilatory nitrate reductase NarB is involved in N2O emissions from common bean nodules. R. etli respiratory nitrite reductase NirK and nitric oxide reductase cNor support N2O production in common bean nodules. R. etli NarB and cNor are involved in NO homeostasis in common bean nodules. R. etli nitrite exporter NarK links nitrate reduction in the cytoplasm with denitrification activities in the periplasm.
Comparative Assessment of the Immunological Significance of Semaphorin 5A and Anti-Cyclic Citrullinated Peptide Antibodies in Iraqi Patients with Rheumatoid Arthritis

The objective of this research was to assess the predictive potential of Semaphorin 5A in comparison to Anti-Cyclic Citrullinated Peptide antibodies for forecasting disease progression and treatment responses among Iraqi patients with Rheumatoid Arthritis (RA). Conducted as a case-control study, the investigation encompassed a total of 150 participants, comprising 100 RA patients and 50 healthy individuals. The study took place at Baghdad Teaching Hospital over the period from November 2021 to February 2022. Enrolled participants were selected based on the 2010 criteria established by the American College of Rheumatology. The levels of biomarkers were assessed using the enzyme-linked immunosorbent assay (ELISA) method. The findings demonstrated a noteworthy elevation in the levels of both ACCP and Semaphorin 5A among RA patients compared to the control group (p<0.001). Furthermore, these levels were found to be higher in individuals with active disease as opposed to those with inactive disease. In both active and inactive disease states, the levels of both ACCP and Semaphorin 5A remained considerably higher compared to the levels observed in the healthy control group (p<0.001). In patients who had not undergone treatment, the levels of both ACCP and Semaphorin 5A exhibited considerably greater significance compared to those who received Methotrexate or etanercept (p<0.001). A noteworthy and positive correlation was observed between ACCP and Semaphorin 5A, with a correlation coefficient of 0.476 (p<0.001). The sensitivity for ACCP and Semaphorin 5A was determined to be 72% and 83% respectively, while the specificity values were 98% and 76%. The study's conclusion highlighted the promising prognostic potential of both ACCP and Semaphorin 5A, establishing them as potential biomarkers for distinguishing between Rheumatoid Arthritis patients and healthy individuals. Predict disease activity and response to methotrexate or etanercept. Active disease patients and without treatments patients ACCP and Semaphorin5A levels were higher than inactive and received treatments (methotrexate or etanercept).
Expression of miRNAs in prostate cancer cell lines and prostate epithelial cell lines

Objectives: Prostate cancer (PCa) is among the most frequently diagnosed cancers and a leading cause of cancer-related deaths in men. Although prostate-specific antigen (PSA) testing has become routine in screening and early detection, PSA has high false-positive rates and poorly correlates with disease stage. Consequently, other diagnostic and prognostic markers for PCa are urgently needed. MicroRNAs (miRNAs) modulate gene expression at the transcriptional level and are known to play key roles in various physiological events. Growing evidence indicates that miRNA dysregulation is involved in the initiation and progression of many diseases, including PCa. Various miRNAs have been associated with PCa pathogenesis, suggesting that miRNA expression profiles have potential utility in the prognosis, diagnosis, and treatment of this disease. miRNA expression levels have been investigated in prostate epithelial cells by PCa cell culture. Methods: The present study compared the expression levels of selected prognostic miRNAs targeting that have been implicated in the pathogenesis of PCa. Using cDNA obtained from the C4-2 human PCa and PNT1a normal prostate epithelial cell lines, miRNA expression levels were quantitatively analyzed via melting curve analysis using the miScript SYBR Green kit in a Rotor-Gene Q real-time polymerase chain reaction (PCR) device. Results: Reverse transcription quantitative PCR analyses have demonstrated miRNA expression levels in the C4-2 PCa cell line and PNT1a prostate epithelial cell line. MiR-125, -145, -200, and -222 were found to be overexpressed in the PCa cell line (p<0.05), while there were no statistically significant differences in miR-32 expression of miR-21, -26, Let-7, -34, or -221 between PCa cells and PNT1a cells (p>0.05). Conclusion: Considering the variation in expression level of miRNAs targeting genes responsible for the etiopathogenesis of PCa. Provides information on the use of miRNAs as prognostic markers in PCa.
Positron binding to alkane molecules

Measurements are presented for the low-energy positron annihilation spectra of the alkane molecules propane through octane. The downshift of the vibrational Feshbach resonances of the infrared-active C-H stretch vibrational modes is used to obtain updated values for the positron-molecule binding energies for these molecules. These binding energies correct previously reported values which had systematic energy shifts due to several small, but signiﬁcant, errors in the analyses. Once these energy shifts are corrected, the old and new measured spectra are in good agreement. This updated analysis procedure is applied to other previously measured alkanes, providing updated binding energies for these molecules. The resulting data are shown to be in good agreement with a recent model-potential calculation and solve issues regarding the interpretation of previous measurements.
Identification of Finger Vein Images with Deep Neural Networks

To establish identification, individuals often utilize biometrics so that their identity cannot be exploited without their consent. Collecting biometric data is getting easier. Existing smartphones and other intelligent technologies can discreetly acquire biometric information. Authentication through finger vein imaging is a biometric identification technique based on a vein pattern visible under finger's skin. Veins are safeguarded by the epidermis and cannot be duplicated. This research focuses on the consistent characteristics of veins in fingers. We collected invariant characteristics from several cutting-edge deep learning techniques before classifying them using multiclass SVM. We used publicly available image datasets of finger veins for this purpose. Several assessment criteria and a comparison of different deep learning approaches were used to characterize the performance and efficiency of these models on the SDUMLA-HMT dataset.