Miracle-dz/UniFAR-FTUs huggingface dataset:
Prevalence and abundance of 9 periodontal pathogens in the saliva of periodontally healthy adults and patients undergoing supportive periodontal therapy

Purpose This study aimed to examine the prevalence and abundance of 9 representative periodontal pathogens in the saliva samples of periodontally healthy subjects (PH) and patients with periodontitis who underwent supportive periodontal therapy (SPT). The age-specific distribution of these pathogens in periodontally healthy individuals was also analyzed. Methods One hundred subjects (aged >35 years) were recruited (50 each in the PH and SPT groups) between August 2016 and April 2019. The prevalence and abundance of periodontal pathogens in the PH group were compared with those in periodontally healthy young subjects (94 subjects; aged <35 years), who were included in our previous study. DNA copy numbers of Aggregatibacter actinomycetemcomitans (Aa), Porphyromonas gingivalis (Pg), Tannerella forsythia (Tf), Treponema denticola (Td), Prevotella intermedia (Pi), Fusobacterium nucleatum (Fn), Campylobacter rectus (Cr), Peptostreptococcus anaerobius (Pa), and Eikenella corrodens (Ec) were analyzed using real-time polymerase chain reaction. Results The detection frequencies of all pathogens, except Aa, were high in the PH and SPT groups. The ranking order of pathogen DNA copy numbers was similar in both groups. In both groups, Fn had the highest abundance, Aa had the lowest abundance. Additionally, Td was significantly more abundant in men than in women in both groups (P<0.05). Compared with the PH group, the SPT group exhibited significantly lower total bacteria and Fn abundance and higher Pg abundance (P<0.05). The age-specific pathogen distribution analysis revealed a significantly low Aa abundance and high Tf and Cr abundance in the PH group. Conclusions The clinical parameters and microbial profiles were similar between the SPT and PH groups. However, patients with periodontitis require supportive care to prevent recurrence. As the abundance of some bacteria varied with age, future studies must elucidate the correlation between age-related physiological changes and periodontal bacterial composition.
Parent-adolescent communication about Sexual and Reproductive Health Issues and Associated Factors among Mothers in Wogdie District, North Ethiopia

Background: Adolescence is a stage of rapid transition of physical, psychological and emotional development. Parent-adolescent communication has great role on the reduction of SRH problem of adolescents. However evidences shows that there is a silence between parent and adolescent because of this adolescent are affected by STIs, HIV, unsafe abortion and unwanted pregnancy. Therefore this study tried to identify factors that hinder communication in Wogdie district North East Ethiopia.Method: A community based cross-sectional study supplemented with qualitative data was conducted. Six hundred fifteen mothers were selected by multi-stage sampling method for quantitative study. Interviewer administered questionnaire was used for quantitative data collection. Multiple binary logistic regression analysis was executed to assess the association between variables. Participants were selected by purposive sampling method for qualitative part. Fourteen participants were participated in in-depth interview. The qualitative data was transcribed manually using verbatim approach.Results: The magnitude of parent-adolescent communication was 198 (32.8%) with 95% CI (29.1, 36.7). Rural residence of mother [AOR=0.056, 95% CI (0.01, 0.331)], family size of >6 [AOR=0.338, 95% CI (0.13, 0.874)], maternal education status of uneducated [AOR=0.421, 95% CI (0.186, 0.951)], maternal occupational status of housewife [AOR=0.085, 95% CI (0.024, 0.298)], low wealth status [AOR=0.316, 95% CI (0.129, 0.777)], poor maternal knowledge about SRH [AOR=0.063, 95% CI (0.024, 0.164)] and negative maternal attitude towards SRH communication [AOR=0.037, 95% CI (0.008, 0.169)] were have significant negative association with parent-adolescent communication. Cultural taboo, fear and lack of knowledge were reasons that hinder communication.Conclusion: Communication on sexual and reproductive health issue between parent and adolescent was low. Home to home and community health education of mothers is important to create good knowledge and positive attitude about sexual and reproductive communication.
Convalescent Plasma Therapy in SARS-COV-2 Infection, Experience in Tucumán Argentina: An Observational Study

Background: Therapies based on different drugs and corticosteroids have been employed to stop the SARS-COV-2 virus infection. The administration of convalescent plasma (CP) is other therapy used to control COVID-19 disease. Aim: To evaluate the efficacy of the CP therapy on the recovery of SARS-COV-2 infection in 189 hospitalized patients who received this treatment during July to October 2020. Material and Methods: 189 patients with COVID-19 requiring hospitalization in the Intensive Care Unit (ICU) or mechanical ventilation, from the public hospital dependent on the Health Ministry of Tucumán, Argentina, were selected to receive plasma. The Convalescent Plasma to be use in the transfusion therapy, was selected according the nucelocapside specific IgG antibody titer, measured by Abbott Architect SARS-CoV-2 assay. Results: We observed that early administration of CP, between3 to 5 days after hospitalization, to patients with moderate disease, was associated with a decrease in the mortality. In 27 patients from the Intensive Care Unit which required mechanical ventilation and 28 patients that presented several comorbidities, plasma administration was effective in 14 and 60% respectively. Conclusion: The results suggest that the favorable effect of CP would be related with the the period of time when plasma was administered to hospitalized patients and the severity of the disease. Early administration was a critical point to decrease the deaths of SARS-COV-2 infected patients.
Comparison of Thermal Ablation and Surgery for Low-Risk Papillary Thyroid Microcarcinoma: A Systematic Review and Meta-Analysis

Objective Although thermal ablation is effective in treating low-risk papillary thyroid microcarcinomas (PTMCs), comparison of treatment outcomes between thermal ablation and surgery has not yet been systematically evaluated. This study aimed to compare the efficacy and safety of thermal ablation and surgery for the treatment of low-risk PTMCs. Materials and Methods Ovid-MEDLINE and EMBASE databases were searched for studies reporting comparisons of treatment results between thermal ablation and surgery for patients with low-risk PTMC published up to April 6, 2020. The analysis evaluated the efficacy (local tumor recurrence, occurrence of new tumor, metastasis, and rescue surgery) and safety (complication rate) of thermal ablation and surgery. Results This systematic review included four studies with a total of 339 PTMCs in 339 patients who underwent thermal ablation and 320 PTMCs in 314 patients who underwent surgery. There was no local tumor recurrence or distant metastasis in either group. There was no significant difference in the pooled proportion of lymph node metastasis (2.6% with thermal ablation vs. 3.3% with surgery, p = 0.65), occurrence of new tumors (1.4% with thermal ablation vs. 1.3% with surgery, p = 0.85), or rescue surgery (2.6% with thermal ablation vs. 1.6% with surgery, p = 0.62). However, the pooled complication rate was significantly higher in the surgery group than in the ablation group (3.3% with thermal ablation vs. 7.8% with surgery, p = 0.03). Conclusion Both thermal ablation and surgery are effective and safe options for the management of low-risk PTMCs, with thermal ablation achieving a lower complication rate. Therefore, thermal ablation may be considered as an alternative treatment option for low-risk PTMC in patients who refuse surgery and active surveillance or are ineligible for surgery.
Effects of warming and nitrogen addition on nutrient resorption efficiency in an alpine meadow on the northern Tibetan Plateau

ABSTRACT The increase in two controversial global environmental issues, climate warming and nitrogen (N) deposition, may have distinct effects on the processes and functioning of terrestrial ecosystems. Nutrient resorption is an important determinant of plant community nutrient dynamics, especially in nutrient-limited ecosystems, but information about N and phosphorus (P) resorption in alpine ecosystems is still lacking. A long-term simulated warming and exogenous N addition experiment initiated in July 2010 was conducted in an alpine meadow in Damxung County in northern Tibet. The experiment consisted of conditions of warming and no warming crossed with three N addition levels: 0 (CK), 20 (N20), and 40 (N40) kg N · ha−1 · year−1. With increasing N addition levels, the N content and the N/P ratio in plant leaves gradually increased, while the P limitation of plant growth was aggravated by N addition. The moderate N addition level (N20) increased plant N resorption efficiency (NRE), while the high N addition level (N40) had no effect on the NRE of Kobresia pygmaea or Anaphalis xylorhiza. N addition significantly increased the P resorption efficiency (PRE) in Stipa capillacea leaves. However, N addition did not change the community NRE or the community PRE. The soil N content decreased under the warming treatment. At the community level, warming significantly increased the NRE by 12% and 16%, and the PRE by 26% and 24% under the CK and N40 treatments, respectively. The NRE and PRE were higher in S. capillacea than in K. pygmaea and A. xylorhiza, especially at the high N addition level (38% and 45% higher NRE and 36% and 15% higher PRE compared to K. pygmaea and A. xylorhiza, respectively). Correlation analysis showed that the NRE and PRE in plant leaves were mainly mediated by soil inorganic N availability, and tended to decrease with increase of soil N availability, suggesting that N loss due to warming could induce changes in nutrient resorption in alpine ecosystems. The species-specific responses to N addition and the stronger competitive advantage of S. capillacea may change the community structure and subsequently affect the decomposition process in this alpine meadow under future global climate change scenarios.
Comparison of Knowledge and Perception of Orthodontic Treatment among Dental Students and Local Population

People’s perception, awareness and knowledge about their occlusion and esthetics has great impact on their attitude towards orthodontic treatment. In order to assess and compare the knowledge and self-awareness of orthodontic problem and treatment need between dental student and local population a survey was conducted As Patient’s self-perception is of significant importance in successful orthodontic treatment planning. The participants included 110 adults including local population and dental students of Punjab and almost most of them were 20-30 years old. The participants’ opinion regarding self-awareness and orthodontic treatment need was recorded on a specifically designed questionnaire. 61.7% people were aware of their occlusion and most of them were dental studens.38. 3% people are afraid of orthodontic treatment due to lack of knowledge and awareness. Dental students had awareness and good knowledge, thus positive attitude towards orthodontics. Local population had little or no knowledge about orthodontic
The Clinical Profile of Distal Third Femoral Shaft Fractures Patients

Original Research Article Objective: In this study our main goal is to evaluate the clinical profile of distal third femoral shaft fractures patients. Method: This prospective observational study was carried out at National Institute of Traumatology and Orthopedic Rehabilitation (NITOR), Dhaka from June 2007 to December 2008. Where a total of 10 patients with distal femoral fractures were selected and treated with open reduction and internal fixation were included in the study. Result: During the study, most of the patients belong to 30-39 years age group and 80% were male. Highest number of patients had right side involvement (60%). (90%) had sustained high-energy trauma while only 10% suffered lowenergy trauma. Also, 50% were operated upon within 1-2 weeks of injury. Conclusion: From our result we can conclude that, most of the patients had right side involvement and majority had sustained high-energy trauma. Early surgery, closed reduction, at least two screws in each fragment and early post-operative knee mobilization are essential for good outcome in patients.
Observing infants together: long-term experiences of observers and families

ABSTRACT Infant observation is a key component of many psychotherapy and psychoanalysis training programs. Observers and families have described the intensity of this unique experience. However, there has been limited investigation of the subsequent experiences of infant observation on observers and on families who had taken part. In the present study, the experiences of observers and families several years following the infant observation period were investigated. We recruited a total of 10 participants, consisting of 7 observers (mean age 53.7 years) and 3 parents (mean age 51.7 years). The length of time since the infant observation was an average of 10.0 years (range 2–16 years). Semi-structured interviews were conducted, and the overarching themes and subthemes were explored using thematic analysis. Both observers and families were able to vividly reflect on the infant observation period. All participants reported developing their observation and reflective skills, which observers who work as psychotherapists described as being crucial to their current practices. Participants keenly felt the loss during the observation period, with some parents feeling a more unresolved loss. In summary, the experience remains present and impactful for both observers and parents for years following the infant observation period.
The clique approach to identifying critical elements in gas transmission networks

We consider the gas transmission network operating on the territory of the Russian Federation. This network includes gas fields, gas consumers, nodal compressor stations, underground gas storages, which, depending on the given scenario of the system operation, can act as gas sources or gas consumers. The nodes are connected by means of gas pipelines. Because natural gas is used in heat and power engineering and electricity, the gas transmission network may be exposed to terrorist threats, and the actions of intruders may be directed both at gas production facilities and gas pipelines. To simulate intruders attacks, a model of the attacker-defender type was proposed. In this model, the defender, represented by the system operator, solves the problem of finding the maximum flow to meet the needs of gas consumers. The attacker, in turn, attempts to minimize the maximum flow in the gas transmission network by excluding either nodes or gas pipelines. Gas transmission networks in Russia and Europe are very extensive, ramified, and have many bridges and reserve gas pipelines. Therefore, to inflict maximum damage to the system, attacks on cliques, that is, on several interconnected objects, are modelled. The article presents the results of test calculations, in which we identify the most significant combinations of objects in the gas transmission network in terms of the potential threat from terrorist attacks.
LSTM-based Energy Management for Electric Vehicle Charging in Commercial-building Prosumers

As typical prosumers, commercial buildings equipped with electric vehicle (EV) charging piles and solar photovoltaic panels require effective energy management method. However, the conventional optimization model-based building energy management system faces significant challenges regarding prediction and calculation in online execution. To address this issue, a long short-term memory (LSTM) recurrent neural network-based machine learning algorithm is proposed in this study to schedule the charging and discharging of numerous EVs in commercial building prosumers. Under the proposed system control structure, the LSTM algorithm can be separated into an offline and online stage. In the offline stage, the LSTM is used to map states (inputs) to decisions (outputs) based on the network training. In the online stage, once the current state is input, the LSTM can quickly generate a solution without any additional prediction. A preliminary data processing rule and an additional output filtering procedure are designed to improve the decision performance of LSTM network. The simulation results demonstrate that the LSTM algorithm can generate near-optimal solutions in milliseconds and significantly reduce the prediction and calculation pressure compared to the conventional optimization algorithm.
A Simulation Study of Significant Wave Height Retrieval From Bistatic Scattering of Signals of Opportunity

Simulation results are used to assist algorithm development for extracting the ocean surface significant wave height (SWH) from microwave scattering of satellite broadcast signals from the ocean surface. The analysis shows that the Doppler frequency spectrum width is a reliable parameter for extracting the SWH. The numerical experiments include both deep and shallow water conditions. The correlation between Doppler frequency spectrum width and SWH is robust and applicable to all wind speeds, inverse wave ages, and water depths tested in this study (5–21 m/s, 0.8–2.0, and 3 m–<inline-formula> <tex-math notation="LaTeX">$\infty $ </tex-math></inline-formula>, respectively).
Preliminary phytochemical study and TLC analysis of the fruit, leaves and flowers of Citrus limetta Risso

Citrus limetta Risso specie belongs to Rutaceae family, commonly known as sweet lime in Mexico. It has traditionally been used for several medicinal purposes. Phytochemical screening and TLC study of fruit, leaves and flowers were made to identify the qualitative presence of main bioactive compounds. Phytochemical analysis was carried out using solvents at different polarity as n-butane, ethanol, methanol, and water. As a result, it was found a high diversity of metabolites such as alkaloids, flavonoids, quinones, steroids, cardiac glycosides, sesquiterpene lactones, tannins, saponins and leucoanthocyanins. At last, a Thin Layer Chromatography (TLC) was used to confirm the presence of alkaloids and flavonoids giving different Rf values. The result showed the presence of alkaloids and flavonoids in fruits, leaves and flowers of Citrus limetta Risso, which can be correlated as a possible potential as anxiolytic, sleep regulator, and antioxidant.
Area and Power Efficient Truncated Booth Multipliers Using Approximate Carry-Based Error Compensation

Approximate computing is a promising technique to elevate the performance of digital circuits at the cost of reduced accuracy in numerous error-resilient applications. Multipliers play a key role in many of these applications. In this brief, we propose a truncation based Booth multiplier with a compensation circuit generated by selective modifications in k-map to circumvent the carry appearing from the truncated part. By judicious mapping, hardware pruning and output error reduction is achieved simultaneously. In the quest of power and accuracy trade-off, Truncated and Approximate Carry based Booth Multipliers (TACBM) are proposed with a range of designs based on truncation factor <inline-formula> <tex-math notation="LaTeX">${w}$ </tex-math></inline-formula>. When compared with the state-of-the-art multipliers, TACBM outperforms in terms of accuracy and Area-Power savings. TACBM(<inline-formula> <tex-math notation="LaTeX">${w}=10$ </tex-math></inline-formula>) provides with 0.02% MRED and 23% reduction in Area-Power product compared to exact Booth multiplier. The multipliers are evaluated using image blending and Multilayer perceptron (MLP) neural network and a high value of accuracy (95.63%) for MLP is achieved.
Incidence of Diabetes Mellitus Type II and Pre-Diabetes among Shoulder Impingement Syndrome Patients and Related Modifying Factors: Epidemiological Study

Objective: Measure the incidence of Diabetes Mellitus (DM) among patients with shoulder impingement syndrome and the factors that can modify that disease. Design: Prospective. Settings: Outpatient. Participants: 412 patients presented with unilateral or bilateral shoulder pain suspecting shoulder impingement neuromuscular diseases, or syndrome. Exclusion criteria: Those having manifestations suggesting of cervical radiculopathy, shoulder trauma history. Interventions: Each patient was subjected to the following; demographic data including occupation, body mass index, detailed medical history including DM history. Shoulder exam including impingement provocative tests; Hawkin test, Neer’s sign. Neck exam including Spurling test. Full neurological exam. Main outcome measures: Laboratory testing including glycosylated hemoglobin (HgA1c), liver and kidney functions. Shoulder MRI if possible. Results: Mean age 59.4 ± 11.123. All patients were right-handed, Male 37.1%, female 62.9%, Mean body mass index (BMI) 32.2 ± 8.2. Majority were manual workers (55.1%). No significant relationship between shoulder impingement sex but significant with BMI and age. HgA1c <5.5 has the fewest patients (7.3%), highest number of patients with HgA1c 5.5-6.0. significant incidence of shoulder impingement with rising category of HgA1c with highest among Hga1c >7 (p=0.0001) with significant bilateral disease. Significant incidence of shoulder impingement (unilateral or bilateral among diabetics (HgA1c >6) compared to non- diabetics (p=0.011). Conclusions: High incidence of DM /prediabetes among shoulder impingement patients. Level of HgA1c significantly proportionate to incidence and laterality. This suggests that it is part of musculoskeletal complication of DM. that can evidently occur with prediabetes status. Body mass index and age significantly affected the incidence but not the sex.
Vertical Accuracy Assessment of Open Access Digital Elevation Models Using GPS

In this study, the vertical accuracy of the Shuttle Radar Topography Mission Digital Elevation Model Version 2.0 (SRTM30), the Advanced Spaceborne Thermal Emission and Reflection Radiometer Global DEM Version 2.0 (ASTER GDEM2), and Advanced Land Observing Satellite World 3D Digital Surface Model Version 2.1 (ALOS AW3D30) was statistically assessed using GPS data. The Tashkent geodynamical polygon was chosen as a study region, where the land surface can reflect as both natural (tectonic) and man-made (Charvak reservoir load effect) processes. The geometric approach using GPS/leveling stations and EGM96 GGM-based geoid undulations was applied for local geoid modeling. RMSE of ~7.48 m, ~6.90 m, and ~8.24 m was obtained for SRTM30, ASTER GDEM2, and ALOS AW3D30, respectively. ASTER GDEM2 proved to be the most accurate DEM with absolute vertical accuracy LE90 of 11.35 m and ME of 5.25 m and it is very suitable for geodetic and hydrological studies in this mountainous area.
Factors of increasing alfalfa yield capacity under conditions of the Forest-Steppe

Saabunud / Received 10.02. 2021 ; Aktsepteeritud / Accepted 02.06. 2021 ; Avaldatud veebis / Published online 02.06. 2021 ; Vastutav autor / Corresponding author: Andrii Butenko andb201727@ukr.net
Management of the Gastrointestinal System Bleeding Caused by Direct-Acting Oral Anticoagulants

Direct-acting oral anticoagulants include dabigatran, which is a thrombin inhibitor, and rivaroxaban, apixaban, and edoxaban, which are anti-Xa agents. These are administered in the secondary prophylaxis and treatment of venous thromboembolism (VTE) and pulmonary embolism (PE), in the prophylaxis of VTE that may develop after major elective orthopedic surgery, in reducing stroke and systemic embolism that may occur in non-valvular atrial fibrillation, whereas its use in acute coronary syndrome is still controversial. Although it is specified that direct-acting oral anticoagulants are as effective as heparin therapy and reduce the risk of bleeding due to all causes, many important studies have also reported that they increase the risk of gastrointestinal system (GIS) bleeding.