Miracle-dz/UniFAR-FTUs huggingface dataset:
Intermittent self‐administration of fentanyl induces a multifaceted addiction state associated with persistent changes in the orexin system

The orexin (hypocretin) system plays a critical role in motivated drug taking. Cocaine self‐administration with the intermittent access (IntA) procedure produces a robust addiction‐like state that is orexin‐dependent. Here, we sought to determine the role of the orexin system in opioid addiction using IntA self‐administration of fentanyl. Different groups of male rats were either given continuous access in 1‐h period (short access [ShA]), 6‐h period (long access [LgA]), or IntA (5 min of access separated by 25 min of no access for 6 h) to fentanyl for 14 days. IntA produced a greater escalation of fentanyl intake, increased motivation for fentanyl on a behavioral economics task, persistent drug seeking during abstinence, and stronger cue‐induced reinstatement compared with rats given ShA or LgA. We found that addiction behaviors induced by IntA to fentanyl were reversed by the orexin‐1 receptor antagonist SB‐334867. IntA to fentanyl was also associated with a persistent increase in the number of orexin neurons. Together, these results indicate that the IntA model is a useful tool in the study of opioid addiction and that the orexin system is critical for the maintenance of addiction behaviors induced by IntA self‐administration of fentanyl.
Bullying in Korean hotel restaurant kitchens: why is everybody always picking on me?

PurposeThe primary purpose of this article is to develop and test a model of the antecedents and consequences (Cho et al., 2016) of bullying in Korean hotel kitchens.Design/methodology/approachCross-sectional survey data were collected from 288 kitchen workers at 12 upscale Korean hotels. Proposed path models were tested using Hayes' (2013) PROCESS syntax in SPSS for mediation and moderated mediation analyses.FindingsThe empirical results indicated that an employee's acquiescent silence behavior increases the likelihood of being bullied. As a result, bullied employees are more likely to respond by engaging in a person-related counterproductive work behavior (CWB-P) or in defensive silence out of fear with temporary employees reacting less aggressively compared to regular employees.Research limitations/implicationsCross-sectional design and self-report data risk common method variance and attributions of causality. Future research should use longitudinal designs to avoid common method bias and make causal inferences. Theoretical and practical implications for kitchen productivity are presented. The study should offer valuable insights for prospective employers to develop on-going training and create a positive working environment within the organization.Originality/valueWhile bullying is a widespread and even an epidemic problem for the commercial kitchen environment, research into abusive behavior among chefs has been limited. By utilizing a specific segment of the hospitality industry, this research identified different behavioral aspects of bulling between temporary and regular employees in the commercial kitchen environment.
HR Professionals’ Intention to Adopt and Use of Artificial Intelligence in Recruiting Talents

Purpose: The present study is an attempt to explore the antecedents of behavioral intention to use artificial intelligence (AI) in recruiting talents by the HR professionals in Bangladesh. Drawing on the principle of the unified theory of acceptance and use of technology (UTAUT), which was built on the premise of technology acceptance model, the theory of planned behavior, the theory of reasoned action, and so forth, the current study has been conducted in the context of Bangladesh. Method: Building on the understanding of the deductive reasoning approach, the investigation followed the positivism paradigm via a quantitative research strategy. We collected 226 replies from the end-users of AI through a self-administrative survey. We used structural equation modeling (SEM) via SmartPLS. Results: Henceforth, the results in the findings filmed that all the hypotheses were supported. Implications: One of the important implications of the present study is the use of the intervention mentioned in this study for the manufacturing and service firms. Limitation: The major limitation is the use of cross-sectional data which implies that future research must use both cross-sectional and longitudinal data for the generalizability of the observed findings.
Financial reporting in family firms: a socioemotional wealth approach toward information quality

ABSTRACT The strategic choices of family firms are influenced by economic and noneconomic reference points. We contend that the preservation of the affect-related values a family derives from its ownership position in a firm (that is, socioemotional wealth [SEW]) affects financial reporting quality and earnings management strategies. Using the voluntary International Financial Reporting Standards (IFRS) adoption by Italian unlisted family firms as a natural laboratory setting, we found that the level of SEW endowment impacts on financial reporting quality. Furthermore, we observe that IFRS adoption is associated with less accrual, but higher real activity manipulation for increasing levels of SEW endowment.
Equality of the wobbly and shaky loci

Let $X$ be a smooth complex projective curve of genus $g\geq 2$. We prove that a parabolic vector bundle $\mathcal{E}$ on $X$ on $X$ is (strongly) wobbly, i.e. $\mathcal{E}$ has a non-zero (strongly) parabolic nilpotent Higgs field, if and only if it is (strongly) shaky, i.e., it is in the image of the exceptional divisor of a suitable resolution of the rational map from the (strongly) parabolic Higgs moduli to the parabolic bundle moduli space, both assumed to be smooth. This solves a conjecture by Donagi-Pantev [DP1] in the parabolic and the vector bundle context. To this end, we prove the stability of strongly very stable parabolic bundles, and criteria for very stability of parabolic bundles.
Outcome of Surgical Closure of Atrial Septal Defect in Sulaimani City

An atrial septal defect (ASD), sometimes called a hole in the heart is a type of congenital heart defect in which there is an abnormal opening in the dividing wall between the upper filling chambers of the heart (the atria). To determine the outcome of surgical closure in patients with atrial septal defects, we designed a retrospective study, including 120 patients present with an atrial septal defect after surgical closure done in the cardiac teaching center in Sulaimani city. The data collected include the patients that admitted which are known cases of ASD and treated by open heart surgery during the last nine years from 1st of January 2008 until the 1st of January 2018. A total of 120 children diagnosed with Atrial Septal Defect (ASD) were included in this study with a mean age of 7.8±4.4 years; 32.5% of them were 1-5 years old, 50.8% of them were in the age group 6-12 years, and 16.7% of them were in the age group 13-19 years. Only three ASD children received medical treatment while all of them were treated surgically with open-heart surgery. The mean age of ASD children at surgery was7.8±4.4 years; 5.8% of them were 1-2 years old, 28.4% of them were 3-5 years old, 49.1% of them were in the age group 6-12 years, and 16.7% of them were in the age group 13-19 years. There was a significant association between primum ASD type and large ASD with posteroinferior deficient rims (P=0.04). A significant association was observed between primum ASD type and large IAS (P=0.006). Mean ASD diameter was significantly higher among patients with primum ASD type (P=0.01). The outcome of surgical closure of the atrial septal defect in children is effective and safe. Ventricular arrhythmia in the form of ectopic was the postoperative complication in one patient. The main echocardiography findings of children with atrial septal defects were large ASD with posteroinferior deficient rims.
Perfluorobutanesulfonic acid (PFBS) induces fat accumulation in HepG2 human hepatoma

Abstract Per- and poly-fluoroalkyl substances, especially perfluorooctanesulfonic acid (PFOS), have been extensively used for over 50 years. A growing body of evidence has emerged demonstrating the potential adverse effects of these substances, including its effect on the development of non-alcoholic fatty liver disease, as one of the most prevalent chronic liver diseases. Nonetheless, there is no report of effects of perfluorobutanesulfonic acid (PFBS), the major replacement for PFOS, on non-alcoholic fatty liver disease. Therefore, the effects of PFBS exposure on fat accumulation in a human hepatoma cell line were examined. Cells were exposed to PFBS with or without 300 μmol/L fatty acid mixture (oleic acid–palmitic acid, 2:1) conjugated by bovine serum albumin as an inducer of steatosis for 48 h. PFBS at 200 μmol/L significantly increased the triglyceride level in the presence of fatty acid compared to the control, but not without fatty acid, which was abolished by a specific peroxisome proliferator-activated receptor gamma antagonist. PFBS upregulated key genes controlling lipogenesis and fatty acid uptake. PFBS treatment also promoted the production of reactive oxygen species, an endoplasmic reticulum stress marker and cytosolic calcium. In conclusion, PFBS increased fat accumulation, in part, via peroxisome proliferator-activated receptor gamma-mediated pathway in hepatoma cells. Abbreviations: ACC: acetyl-CoA carboxylase; CD36: cluster of differentiation 36; CHOP: CCAAT/enhancer-binding homologous protein; CPT1α: carnitine palmitoyltransferase 1α; DDIT3: DNA damage-inducible transcript 3; DGAT2: diacylglycerol O-acyltransferase 2; ER: endoplasmic reticulum; FA: fatty acid; FAS: fatty acid synthase; NAFLD: nonalcoholic fatty liver disease; NF-κB: nuclear factor kappa B; PFAS: per- and polyfluoroalkyl substances; PFBS: perfluorobutanesulfonic acid; PFOS: perfluorooctanesulfonic acid; PPAR: peroxisome proliferator-activated receptor; ROS: reactive oxygen species; SREBP1: sterol regulatory element-binding protein 1; TG: triglyceride; TNF-α: tumor necrosis factor alpha; UPR: unfolded protein response
Application and Research of Naive Bayes Algorithm in Spam Filtering

: With the advent of the 5G era, the scope of e-mail applications has become more and more extensive, but the various spam messages that follow have also caused more and more serious problems. Among the many existing methods for filtering spam, the probability-based Bayesian classification algorithm is simple and efficient, and the accuracy rate can reach about 90%. This article briefly introduces the Bayesian model, gives an email filtering method based on the naive Bayesian classification model, and briefly analyzes its advantages and disadvantages. Finally, its effectiveness is verified through experiments.
High-Fidelity Control of Superconducting Qubits Using Direct Microwave Synthesis in Higher Nyquist Zones

Control electronics for superconducting quantum processors have strict requirements for accurate command of the sensitive quantum states of their qubits. Hinging on the purity of ultra-phase-stable oscillators to upconvert very-low-noise baseband pulses, conventional control systems can become prohibitively complex and expensive when scaling to larger quantum devices, especially as high sampling rates become desirable for fine-grained pulse shaping. Few-gigahertz radio-frequency (RF) digital-to-analog converters (DACs) present a more economical avenue for high-fidelity control while simultaneously providing greater command over the spectrum of the synthesized signal. Modern RF DACs with extra-wide bandwidths are able to directly synthesize tones above their sampling rates, thereby keeping the system clock rate at a level compatible with modern digital logic systems while still being able to generate high-frequency pulses with arbitrary profiles. We have incorporated custom superconducting qubit control logic into off-the-shelf hardware capable of low-noise pulse synthesis up to 7.5 GHz using an RF DAC clocked at 5 GHz. Our approach enables highly linear and stable microwave synthesis over a wide bandwidth, giving rise to high-resolution control and a reduced number of required signal sources per qubit. We characterize the performance of the hardware using a five-transmon superconducting device and demonstrate consistently reduced two-qubit gate error (as low as 1.8%), which we show results from superior control chain linearity compared to traditional configurations. The exceptional flexibility and stability further establish a foundation for scalable quantum control beyond intermediate-scale devices.
From conventional to electrically-assisted cycling. A biographical approach to the adoption of the e-bike

Abstract Sales of electrically-assisted bicycles (e-bikes) have been rising in many European countries. Due to their electrical assistance, e-bikes could increase the number of people cycling and the potential uses of cycling. Existing research has not investigated the links between conventional cycling and e-bike use at the individual level. Using qualitative, retrospective data, this paper aims to determine how e-bike use fits into an existing cycling trajectory over the life course. E-bike users in the Swiss city of Lausanne (N = 24) are interviewed to compare their cycling trajectories. They fall into two main trajectories: “restorative” and “resilient”, which each represent different relationships to cycling and different reasons to adopt the e-bike over the life course. E-bikes might serve as both a way to restore an interrupted cycling practice, or to keep existing cyclists despite threats posed by changing personal and spatial contexts.
The Effects of the Ambient Pressure on Self-Pulsation Characteristics of a Gas/Liquid Swirl Coaxial Injector

Self-pulsation gas strong influences on the atomization and mixing process and accompanies strong noises. A strong pressure and flow rate oscillation are detected when self-pulsation occurs. A sharp and narrow increase in frequency spectrum by self-pulsation is observed at a certain frequency. In this study, the effects of the ambient pressure on selfpulsation characteristics of a gas/liquid swirl coaxial injector are studied experimentally. A gas/liquid swirl coaxial injector is mounted in the high pressure chamber and the ambient pressure increased up to 1 MPa. The spray patterns were investigated according to the ambient pressure using digital camera and stroboscope. Also, acoustic and spray characteristics of self-pulsation are investigated with various injection and recess length conditions using acoustic device and laser system. From the results, it is found that the ambient pressure has great effects on self-pulsation and the mechanism of self-pulsation is suggested. Nomenclature do = inner orifice diameter Pc = chamber pressure Reg = axial gas Reynolds number Rel = axial liquid Reynolds number RR = recess ratio vg = axial gas velocity vl = axial liquid velocity ρg = gas density ρL = liquid density
A sorghum NAC gene is associated with variation in biomass properties and yield potential

Abstract Sorghum bicolor is a C4 grass widely cultivated for grain, forage, sugar, and biomass. The sorghum Dry Stalk (D) locus controls a qualitative difference between juicy green (dd) and dry white (D‐) stalks and midribs, and co‐localizes with a quantitative trait locus for sugar yield. Here, we apply fine‐mapping and genome‐wide association study (GWAS) to identify a candidate gene underlying D, and use nearly isogenic lines (NILs) to characterize the transcriptional, compositional, and agronomic effects of variation at the D locus. The D locus was fine‐mapped to a 36 kb interval containing four genes. One of these genes is a NAC transcription factor that contains a stop codon in the NAC domain in the recessive (dd) parent. Allelic variation at D affects grain yield, sugar yield, and biomass composition in NILs. Green midrib (dd) NILs show reductions in lignin in stalk tissue and produce higher sugar and grain yields under well‐watered field conditions. Increased yield potential in dd NILs is associated with increased stalk mass and moisture, higher biomass digestibility, and an extended period of grain filling. Transcriptome profiling of midrib tissue at the 4–6 leaf stages, when NILs first become phenotypically distinct, reveals that dd NILs have increased expression of a miniature zinc finger (MIF) gene. MIF genes dimerize with and suppress zinc finger homeodomain (ZF‐HD) transcription factors, and a ZF‐HD gene is associated with midrib color variation in a GWAS analysis across 1,694 diverse sorghum inbreds. A premature stop codon in a NAC gene is the most likely candidate polymorphism underlying the sorghum D locus. More detailed understanding of the sorghum D locus could help improve agronomic potential in cereals.
Assimilating and Differentiating: The Curvilinear Effect of Social Class on Green Consumption

Building on optimal distinctiveness theory, this research examines the effects of social class on green consumption. Across six studies, we find a curvilinear effect of social class on green consumption, with the middle class having greater propensity for green consumption compared to the lower and upper classes. This effect can be explained by tension between need for assimilation (NFA) and need for differentiation (NFD) that varies among the three social classes in establishing their optimally distinctive identities. The lower class has a dominant NFA, the upper class has a dominant NFD, and the middle class has dual motivation for assimilation and differentiation. Concomitantly, green consumption has the dual function of assimilation and differentiation. The middle class perceives green consumption as simultaneously assimilating and differentiating, which satisfies their dual motivation and enhances their propensity for green consumption. By contrast, the lower class perceives the differentiation function of green consumption as contradicting their dominant NFA, and the upper class perceives the assimilation function as contradicting their dominant NFD, which lower both their propensities for green consumption. Furthermore, these effects are moderated by consumers’ power distance belief. These novel findings have significant theoretical and practical implications on building a more sustainable society.
A Novel Approach for Automatic Detection of Concrete Surface Voids Using Image Texture Analysis and History-Based Adaptive Differential Evolution Optimized Support Vector Machine

To inspect the quality of concrete structures, surface voids or bugholes existing on a concrete surface after the casting process needs to be detected. To improve the productivity of the inspection work, this study develops a hybrid intelligence approach that combines image texture analysis, machine learning, and metaheuristic optimization. Image texture computations employ the Gabor filter and gray-level run lengths to characterize the condition of a concrete surface. Based on features of image texture, Support Vector Machines (SVM) establish a decision boundary that separates collected image samples into two categories of no surface void (negative class) and surface void (positive class). Furthermore, to assist the SVM model training phase, the state-of-the-art history-based adaptive differential evolution with linear population size reduction (L-SHADE) is utilized. The hybrid intelligence approach, named as L-SHADE-SVM-SVD, has been developed and complied in Visual C#. NET framework. Experiments with 1000 image samples show that the L-SHADE-SVM-SVD can obtain a high prediction accuracy of roughly 93%. Therefore, the newly developed model can be a promising alternative for construction inspectors in concrete quality assessment.
Teacher change through cognitive conflicts: the case of an art lesson study

The paper focuses on lesson study, which generally engages the collaborative work of a group of teachers, as implemented with a primary school art teacher who had limited opportunities for collaboration. Through lesson study, the teacher worked closely with a lesson study facilitator and an art education expert to plan a research lesson. The study explores how this collaboration generated cognitive conflicts and eventually teacher change. ,This paper presents a case study using a thematic approach to data analysis. The lesson study involved weekly face-to-face meetings and daily online communications over a period of eight weeks. In an attempt to reflect upon and resolve conflicts, the teacher kept a journal in which the teacher wrote down lengthy accounts of the discussions with knowledgeable others, the teacher’s struggles and ways of resolving these. Data were complemented by the different lesson plan versions, the post-lesson discussions and a detailed report documenting the lesson study process. ,The paper provides insights into the role that cognitive conflicts play for teacher change. Through ongoing communication, reflection and support to resolve conflicts, the teacher recognised more collaborative opportunities for professional development, freed from rigid lesson planning practices and reported a new conceptualisation to teaching. ,Drawing on the literature about effective teacher professional learning, the paper offers implications for supporting teacher change. ,This paper provides insights into how lesson study may provide conditions that enable teachers' cognitive conflict and facilitate their consequent resolution.
Analyse squentielle de l'Eocne et de l'Oligocne du bassin Parisien (France)

Dans le Bassin parisien pendant l'Eocene et l'Oligocene, on denombre vingt-deux discontinuites issues d'emersions correspondant aux periodes de bas-niveaux marins. La presence de fleuves est decelee dans les prismes de bordure de plate-forme et dans les prismes de haut niveau, remobilisant des stocks sableux anciens a partir des anticlinaux actifs et des bordures du bassin. Ainsi, independamment du volume disponible pour les sediments, se succedent des sequences dominees soit par des formations detritiques, soit par des formations carbonatees. La plate-forme parisienne a enregistre toutes les variations eustatiques connues, bien que les mouvements tectoniques syn-sedimentaires locaux puissent influencer fortement les conditions de sedimentation. Mieux encore, la plate-forme parisienne a subi des fluctuations marines d'ordre superieur de tres courte duree qui, si elles sont retrouvees dans d'autres domaines, pourront etre attribuees a des phenomenes eustatiques.