Miracle-dz/UniFAR-FTUs huggingface dataset:
Assessment of Outdoor Terrestrial Gamma Dose Rates in the Konya-Ilgın-Çavuşçu Lignite Deposit (Turkey)

Abstract: This study assesses the terrestrial gamma radiation dose rates from the naturally occurring radionuclides in the lignite coalfield of Ilgin district of Konya. The measurements were performed above the surface soil using NaI(Tl) gamma-ray detector. The average external annual effective doseswere also calculated using these terrestrial gamma radiation dose rates for each measurement location. Key words: Gamma dose rate, Ilgin lignite deposit, terrestrial radiation Konya-Ilgin-Cavuscu Linyit Maden Yataginda Dis Ortam Gama Doz Oranlarinin Belirlenmesi Ozet: Bu calismada Konya’nin Ilgin ilcesindeki linyit komur yatagindaki dogal olarak olusmus radyoaktif cekirdeklerden kaynaklanan karasal gama doz oranlari belirlenmistir. Olcumler, toprak yuzeyinin ustunde ve NaI(Tl) gama-isin detektoru kullanilarak gerceklestirilmistir. Ayrica, olculen bu karasal gama doz oranlari kullanilarak her bir olcum noktasi icin ortalama harici yillik etkin dozlar hesaplanmistir. Anahtar kelimeler: Gama doz orani, Ilgin linyit yatagi, karasal radyasyon
Dual Quaternions for Rigid Transformation Blending

Quaternions have been a popular tool in 3D computer graphics for more than 20 years. However, classical quaternions are restricted to the representation of rotations, whereas in graphical applications we typically work with rotation composed with translation (i.e., a rigid transformation). Dual quaternions represent rigid transformations in the same way as classical quaternions represent rotations. In this paper we show how to generalize established techniques for blending of rotations to include all rigid transformations. Algorithms based on dual quaternions are computationally more efficient than previous solutions and have better properties (constant speed, shortest path and coordinate invariance). For the specific example of skinning, we demonstrate that problems which required considerable research effort recently are trivial to solve using our dual quaternion formulation. However, skinning is only one application of dual quaternions, so several further promising research directions are suggested in the paper.
Identifying Motifs in Folktales using Topic Models

With the undertake of various folktale digitalization initiatives, the need for computational aids to explore these collections is increasing. In this paper we compare Labeled LDA (L-LDA) to a simple retrieval model on the task of identifying motifs in folktales. We show that both methods are well able to successfully discriminate between relevant and irrelevant motifs. L-LDA represents motifs as distributions over words. In a second experiment we compare the quality of these distributions to those of a simple baseline that ranks words using a TF IDF weighting scheme. We show that both models produce representations that match relatively well to a manually constructed motif classication system used in folktale research. Finally we show that unlike L-LDA, this simple baseline is capable of representing abstract motifs as generalizations over more specic motifs.
Clinical Efficacy and Gut Microbiota Regulating-Related Effect of Si-Jun-Zi Decoction in Postoperative Non-Small Cell Lung Cancer Patients: A Prospective Observational Study

Background: Postoperative non-small cell lung cancer (NSCLC) patients frequently encounter a deteriorated quality of life (QOL), disturbed immune response, and disordered homeostasis. Si-Jun-Zi Decoction (SJZD), a well-known traditional Chinese herbal formula, is frequently employed in clinical application for many years. Exploration is underway to investigate the potential therapeutic effect of SJZD for treating postoperative NSCLC. Objective: To assess the efficacy of SJZD on QOLs, hematological parameters, and regulations of gut microbiota in postoperative NSCLC patients. Methods: A prospective observational cohort study was conducted, enrolling 65 postoperative NSCLC patients between May 10, 2020 and March 15, 2021 in Yueyang Hospital, with 33 patients in SJZD group and 32 patients in control (CON) group. The SJZD group comprised of patients who received standard treatments and the SJZD decoction, while the CON group consisted of those only underwent standard treatments. The treatment period was 4 weeks. The primary outcome was QOL. The secondary outcomes involved serum immune cell and inflammation factor levels, safety, and alterations in gut microbiota. Results: SJZD group showed significant enhancements in cognitive functioning (P = .048) at week 1 and physical functioning (P = .019) at week 4. Lung cancer-specific symptoms included dyspnea (P = .001), coughing (P = .008), hemoptysis (P = .034), peripheral neuropathy (P = .019), and pain (arm or shoulder, P = .020, other parts, P = .019) eased significantly in the fourth week. Anemia indicators such as red blood cell count (P = .003 at week 1, P = .029 at week 4) and hemoglobin (P = .016 at week 1, P = .048 at week 4) were significantly elevated by SJZD. SJZD upregulated blood cell cluster differentiation (CD)3+ (P = .001 at week 1, P < .001 at week 4), CD3+CD4+ (P = .012 at week 1), CD3+CD8+ (P = .027 at week 1), CD19+ (P = .003 at week 4), increased anti-inflammatory interleukin (IL)-10 (P = .004 at week 1, P = .003 at week 4), and decreased pro-inflammatory IL-8 (P = .004 at week 1, p = .005 at week 4). Analysis of gut microbiota indicated that SJZD had a significant impact on increasing microbial abundance and diversity, enriching probiotic microbes, and regulating microbial biological functions. Conclusions: SJZD appears to be an effective and safe treatment for postoperative NSCLC patients. As a preliminary observational study, this study provides a foundation for further research.
Statistical imaging and complexity regularization

We apply complexity regularization to statistical ill-posed inverse problems in imaging. We formulate a natural distortion measure in image space and develop nonasymptotic bounds on estimation performance in terms of an index of resolvability that characterizes the compressibility of the true image. These bounds extend previous results that were obtained under simpler observational models.
Klasifikasi Dan Pencarian Buku Referensi Akademik Menggunakan Metode Naïve Bayes Classifier (NBC) (Studi Kasus: Perpustakaan Daerah Provinsi Kalimantan Timur)

Buku merupakan salah satu elemen penunjang dalam proses belajar mengajar, baik itu di sekolah maupun perguruan tinggi. Salah satu tempat yang menyediakan akses untuk mendapatkan buku tersebut adalah Perpustakaan Daerah Provinsi Kalimantan Timur. Kebanyakan penggunjung sulit mendapatkan buku referensi yang tepat sesuai dengan kebutuhan mereka. Hal itu dikarenakan kurangnya fasilitas yang dapat mengklasifikasi buku-buku tersebut sesuai dengan kategorinya. Klasifikasi buku merupakan proses pengelompokkan buku sesuai dengan kategori yang dimilikinya. Sebuah buku dapat dikelompokkan ke dalam kategori tertentu berdasarkan kata-kata yang terkandung pada judul buku tersebut. Penelitian ini bertujuan untuk membuat aplikasi klasifikasi dan pencarian buku yang dapat mengatasi masalah-masalah yang berkaitan dengan pengkategorian dan pencarian buku dengan lebih mudah dan akurat. Aplikasi ini dibangun menggunakan bahasa pemrograman PHP, database MySQL, dan menggunakan metode Naive Bayes Classiffier (NBC). Kategori buku yang digunakan ada lima, yaitu: pemrograman komputer, jaringan komputer, database komputer, multimedia, dan sistem operasi. Dengan mengimplementasikan metode NBC dan kelima kategori tersebut, maka dihasilkan sebuah aplikasi klasifikasi dan pencarian di Perpustakan Daerah Provinsi Kalimantan Timur.
Effects of anthropogenic land cover change on the carbon cycle of the last millennium

Transient simulations are performed over the entire last millennium with a general circulation model that couples the atmosphere, ocean, and the land surface with a closed carbon cycle. This setup applies a high‐detail reconstruction of anthropogenic land cover change (ALCC) as the only forcing to the climate system with two goals: (1) to isolate the effects of ALCC on the carbon cycle and the climate independently of any other natural and anthropogenic disturbance and (2) to assess the importance of preindustrial human activities. With ALCC as only forcing, the terrestrial biosphere experiences a net loss of 96 Gt C over the last millennium, leading to an increase of atmospheric CO2 by 20 ppm. The biosphere‐atmosphere coupling thereby leads to a restoration of 37% and 48% of the primary emissions over the industrial (A.D. 1850–2000) and the preindustrial period (A.D. 800–1850), respectively. Because of the stronger coupling flux over the preindustrial period, only 21% of the 53 Gt C preindustrial emissions remain airborne. Despite the low airborne fraction, atmospheric CO2 rises above natural variability by late medieval times. This suggests that human influence on CO2 began prior to industrialization. Global mean temperatures, however, are not significantly altered until the strong population growth in the industrial period. Furthermore, we investigate the effects of historic events such as epidemics and warfare on the carbon budget. We find that only long‐lasting events such as the Mongol invasion lead to carbon sequestration. The reason for this limited carbon sequestration is indirect emissions from past ALCC that compensate carbon uptake in regrowing vegetation for several decades. Drops in ice core CO2 are thus unlikely to be attributable to human action. Our results indicate that climate‐carbon cycle studies for present and future centuries, which usually start from an equilibrium state around 1850, start from a significantly disturbed state of the carbon cycle.
Creating Sustainable Relationships Using the Strengths, Opportunities, Aspirations and Results Framework, Trust, and Environmentalism: A Research-Based Case Study

New forms of organization development are moving from a classical diagnostic perspective to a dialogic perspective. This move includes a focus on exploring positive states of organizing, shared aspirations, and the design of preferred futures as key outcomes of a strategic change process. Training and development that applies the elements of the strengths, opportunities, aspirations and results (SOAR) framework allows for stakeholders to engage in a dialogue that represents the whole system, and builds trust and environmental management systems that can positively impact supplier performance. In this study, we examined the interrelationship between the SOAR framework, trust, environmental management systems, and supplier performance in respect of 71 program managers and customers from the Hass TCM Group, the largest chemical management services provider in North America. Hypothesis testing was carried out using correlation analysis, multiple linear regression, correlation analysis and Sobel's test for mediation. Our results support a combined framework in which the SOAR framework can be used to build trust and pro-environmental behaviors to train suppliers to develop collaborative relationships with customers.
Effect of using some dietary fibers on color, texture and sensory properties of strained yogurt.

The aim of this study was to search the effects of using some dietary fibers on color, texture and sensory properties of strained yogurts. Apple, wheat and bamboo fibers were used in the production of strained yogurt at different ratios (1%, 2% and 3%). Color, texture values and sensory evaluation scores of samples were analyzed at the 1 st , 7 th , 14 th and 21 st days of storage. Depending on storage, the most changed textural parameter is consistency in bamboo, wheat and apple fibrous strained yogurt. L, a and b values of apple fibrous strained yogurts were determined to be different in comparison with bamboo and wheat fibrous strained yogurts due to the structure of apple fiber. The type of dietary fiber caused statistically significant changes in color, texture values and sensory evaluation scores. Apple fibrous strained yogurts weren’t preferred by panelists because of their ragged structure, dominant apple taste and strong odor. Panelists found bamboo and wheat fiber strained yogurts acceptable. Analyses were done in two replications with their parallels.
Establishing Trust In Pure Ad-hoc Networks

An ad-hoc network of wireless nodes is a temporarily formed network, created, operated and managed by the nodes themselves. It is also often termed an infrastructure-less, self-organized, or spontaneous network. Nodes assist each other by passing data and control packets from one node to another, often beyond the wireless range of the original sender. The execution and survival of an ad-hoc network is solely dependent upon the cooperative and trusting nature of its nodes.However, this naive dependency on intermediate nodes makes the ad-hoc network vulnerable to passive and active attacks by malicious nodes. A number of protocols have been developed to secure ad-hoc networks using cryptographic schemes, but all rely on the presence of an omnipresent, and often omniscient, trust authority. As this paper describes, dependence on a central trust authority is an impractical requirement for ad-hoc networks. We present a model for trust-based communication in ad-hoc networks that also demonstrates that a central trust authority is a superfluous requirement. The model introduces the notion of belief and provides a dynamic measure of reliability and trustworthiness in an ad hoc network.
Low-Dose Glucocorticoid Therapy Complements the Pituitary-Adrenocortical System and Reduces Anxiety and Insomnia in Myasthenia Gravis Patients

AbstractMyasthenia gravis (MG) is an autoimmune disorder generally mediated by antibodies against the acetylcholine receptors of the skeletal muscles. Depending on the disease burden, MG patients may experience chronic dysregulation of both the hormonal stress axis and the immune system, consequently, aggravating the disease itself but also leading to secondary psychopathological abnormalities. A long-term clinical course requires long-term glucocorticoid (GC) therapy, which may change the psychological state by affecting the pituitary-adrenocortical system in MG patients. In this study, we investigated the function of the pituitary-adrenocortical system in MG patients who were treated with prednisolone (PSL) and evaluated their quality of life by using the Medical Outcomes Study 36-item Short-Form Health Survey and the 28-item general health questionnaire (GHQ-28). ACTH and cortisol levels in the plasma of patients who were treated with PSL (PSL[+] group, n = 18) were lower than those in the plasma of patients who were treated without PSL (PSL[−] group, n = 29; P < 0.05 and P < 0.01, respectively). In the PSL(+) group, we confirmed that cortisol levels negatively correlated with daily PSL dosages (P < 0.05). The anxiety and depression scores from the GHQ-28 in the PSL(+) group were lower than those in the PSL(−) group (P < 0.05, respectively). There was no significant correlation between cortisol levels and corticotropin levels in plasma of the PSL(−) group. However, we confirmed that corticotropin levels positively correlated with cortisol levels in plasma (P < 0.01) and negatively correlated with anxiety/insomnia scores from the GHQ-28 (P < 0.05) in the PSL(+) group. In conclusion, low-dose GC treatment complemented the pituitary-adrenocortical system and improved the psychological state in MG patients.
Positron Emission Tomography Compartmental Models: A Basis Pursuit Strategy for Kinetic Modeling

A kinetic modeling approach for the quantification of in vivo tracer studies with dynamic positron emission tomography (PET) is presented. The approach is based on a general compartmental description of the tracer's fate in vivo and determines a parsimonious model consistent with the measured data. The technique involves the determination of a sparse selection of kinetic basis functions from an overcomplete dictionary using the method of basis pursuit denoising. This enables the characterization of the systems impulse response function from which values of the systems macro parameters can be estimated. These parameter estimates can be obtained from a region of interest analysis or as parametric images from a voxel-based analysis. In addition, model order estimates are returned that correspond to the number of compartments in the estimated compartmental model. Validation studies evaluate the methods performance against two preexisting data led techniques, namely, graphical analysis and spectral analysis. Application of this technique to measured PET data is demonstrated using [11C]diprenorphine (opiate receptor) and [11C]WAY-100635 (5-HT1A receptor). Although the method is presented in the context of PET neuroreceptor binding studies, it has general applicability to the quantification of PET/SPECT radiotracer studies in neurology, oncology, and cardiology.
Resource Allocation for Secure Multicarrier AF Relay System Under Total Power Constraint

In this letter, we consider an amplify-and-forward-relay-aided secure multicarrier communication between two nodes with an eavesdropper. We solve the sum secrecy rate maximization problem by solving the following two problems: 1) subcarrier usage policy at the source and the relay; and 2) power allocation among subcarriers between the source and the relay under a total system power constraint. We provide a suboptimal closed-form solution to the problem that involves mixed-integer variables and a nonlinear fractional function. The numerical results demonstrate an improved sum rate by the proposed scheme over a scenario without relay.
Cognitive Function and Participation of Stroke Survivors Living With Companion Animals: A Cross-Sectional Study

Introduction/Objectives: Companion animals (CAs) may benefit human health, but few studies have examined their impact on stroke survivors. This study examines participation, quality of life (QoL), attachment, cognition, and executive function differences between stroke survivors living with and without CAs. Methods: In this cross-sectional, community-setting study, 25 stroke survivors with a CA and a matched group of 27 without a CA completed standard tools. Results: Stroke survivors with a CA scored significantly higher in participation and 1 cognitive performance test. No significant differences were found in other cognitive measures or QoL, and attachment to a CA was not correlated with participation or QoL within the research group. However, lower attachment avoidance correlated with better participation in survivors living with dogs. Conclusion: Living with CAs, especially dogs, might be associated with some cognitive function and participation benefits among stroke survivors. The link between CAs and cognitive function is unclear: Survivors with higher cognitive functioning might be more capable of caring for a CA, or having and caring for a CA might promote better cognitive function. Attachment patterns also might explain stroke survivors’ participation levels. Further study is warranted.
PV harmonic distribution analysis for various conditions

Solar sources require using power converters introducing harmonics in the output waveforms. Data used is the solar radiation and temperature in Halifax, Nova Scotia, Canada. In this work we studied the effect of changing the blanking angle of the square-wave inverter with 60Hz switching. The harmonics are evaluated for various temperatures and solar radiation for the optimum firing angle. Also probability density function is obtained for this case. The effect of the weather parameters on each harmonic component and on the fundamental are evaluated. Showing the variability in the amplitude of each harmonic component will allow for the determinations of where to put emphasis on the sizing of filtering system. Different loads and their effect on the THD and signal smoothing due to the variable weather conditions are also studied.
Steroid receptor coactivator 1 promotes human hepatocellular carcinoma invasiveness through enhancing MMP‐9

Abstract SRC‐1 functions as a transcriptional coactivator for steroid receptors and various transcriptional factors. Notably, SRC‐1 has been implicated in oncogenic roles in multiple cancers, including breast cancer and prostate cancer. Previous investigations from our laboratory have established the high expression of SRC‐1 in human HCC specimens, where it accelerates HCC progression by enhancing Wnt/beta‐catenin signalling. In this study, we uncover a previously unknown role of SRC‐1 in HCC metastasis. Our findings reveal that SRC‐1 promotes HCC metastasis through the augmentation of MMP‐9 expression. The knockdown of SRC‐1 effectively mitigated HCC cell metastasis both in vitro and in vivo by suppressing MMP‐9 expression. Furthermore, we observed a positive correlation between SRC‐1 mRNA levels and MMP‐9 mRNA levels in limited and larger cohorts of HCC specimens from GEO database. Mechanistically, SRC‐1 operates as a coactivator for NF‐κB and AP‐1, enhancing MMP‐9 promoter activity in HCC cells. Higher levels of SRC‐1 and MMP‐9 expression are associated with worse overall survival in HCC patients. Treatment with Bufalin, known to inhibit SRC‐1 expression, significantly decreased MMP‐9 expression and inhibited HCC metastasis in both in vitro and in vivo settings. Our results demonstrated the pivotal role of SRC‐1 as a critical modulator in HCC metastasis, presenting a potential therapeutic target for HCC intervention.
Quantification of sequence exchange events between PMS2 and PMS2CL provides a basis for improved mutation scanning of lynch syndrome patients

Heterozygous mutations in PMS2 are involved in Lynch syndrome, whereas biallelic mutations are found in Constitutional mismatch repair‐deficiency syndrome patients. Mutation detection is complicated by the occurrence of sequence exchange events between the duplicated regions of PMS2 and PMS2CL. We investigated the frequency of such events with a nonspecific polymerase chain reaction (PCR) strategy, coamplifying both PMS2 and PMS2CL sequences. This allowed us to score ratios between gene and pseudogene‐specific nucleotides at 29 PSV sites from exon 11 to the end of the gene. We found sequence transfer at all investigated PSVs from intron 12 to the 3′ end of the gene in 4 to 52% of DNA samples. Overall, sequence exchange between PMS2 and PMS2CL was observed in 69% (83/120) of individuals. We demonstrate that mutation scanning with PMS2‐specific PCR primers and MLPA probes, designed on PSVs, in the 3′ duplicated region is unreliable, and present an RNA‐based mutation detection strategy to improve reliability. Using this strategy, we found 19 different putative pathogenic PMS2 mutations. Four of these (21%) are lying in the region with frequent sequence transfer and are missed or called incorrectly as homozygous with several PSV‐based mutation detection methods. Hum Mutat 31:578–587, 2010. © 2010 Wiley‐Liss, Inc.
The design and implementation of a policy framework for the future Internet

Policy has become an important factor in network design, and there is now a bewildering bevy of architectural proposals. Each one aims at a different set of policy goals, and we don’t know which one is right. This paper’s animating assumption is that we can’t predict the future policy requirements of the Internet so should instead seek the most general policy framework we can possibly implement. To that end, we articulate a general policy principle and describe the design, implementation in hardware, and evaluation of its enforcing mechanism.