Miracle-dz/UniFAR-FTUs huggingface dataset:
A SYSTEMATIC INVESTIGATION OF COMMON GRADIENT BASED MODEL UPDATING APPROACHES APPLIED TO HIGH-FIDELITY TEST-DATA OF A WIND TURBINE ROTOR BLADE

Within the context of the “SmartBlades2”-project, a wind turbine rotor blade was designed and extensively tested. The rotor-blade uses a lightweight composite structure and bend-twist coupling. The bend-twist coupling facilitates a passive load-reduction by changing the angle of attack under load. Due to a high sensor-density of 265 accelerometers in the experimental modal test of the blade, the sophisticated structural dynamics of the model are captured. Apart from the commonly measured first flapwise-, edgewise-bending and torsion mode, 35 modes up to a frequency of 60 Hz are identified. Unlike in many other wind turbine rotor blade investigations, the Finite Element (FE) model uses shell elements instead of beam elements and is directly based on production drawings. This experimental and simulative setup is particularly relevant, since a significant number of mode shapes exhibit a distinct local behavior which was in previous studies not accounted for. The differences between experimental and simulated results are minimized using computational model updating procedures. In this case-study, two formerly underrepresented aspects of the updating of large-scale FE models are examined. One is the use of different parameterizations and the other is the possibility of insufficient experimental data. The parametrizations are based on well-established criteria like error-localization and sensitivity. Moreover, the updating is performed with different (i.e. reduced) subsets of the modal data and the results are then compared to the model updating results achieved with the entire dataset. This in-depth investigation of the model updating of a composite structure allows the deduction of general guidelines in the model updating of industrial-sized FE models. 2159 EURODYN 2020 XI International Conference on Structural Dynamics M. Papadrakakis, M. Fragiadakis, C. Papadimitriou (eds.) Athens, Greece, 23–26 November 2020 Available online at www.easdprocedia. org EASD Procedia EURODYN (2020) 2159-2174 ISSN:2311-9020 © 2020 The Authors. Published by EASD Procedia. Peer-review under responsibility of the Organizing Committee of EURODYN 2020. doi: 10.47964/1120.9175. 19508 J. Knebusch, J. Gundlach and Y. Govers
Impact of stoma on lifestyle and health-related quality of life in patients living with stoma: A cross-sectional study

INTRODUCTION: A person with colostomy or ileostomy undergoes a comprehensive treatment with a wide range of adjustments which affect the individual's social and psychological functioning. Quality of life (QOL) is a subjective feeling which includes physical, social, psychological, and spiritual domains of an individual that can be affected by a stoma. AIM: This study is aimed at identifying the QOL and impact of stoma on their lifestyle pattern among ostomates attending stoma outpatient department of gastroenterology department of a government tertiary care center in South India during 2018. METHODS: A descriptive study using a cross-sectional survey design was conducted among 55 ostomates, following consecutive sampling technique. The data were collected using a City of Hope QOL Questionnaire for Ostomy patients which had QOL Assessment Questions from four subdomains including physical, psychological, social, and spiritual aspects. This tool also had open-ended questions on lifestyle assessment components. RESULTS: 63.6% of the participants had colostomy; 72.7% of the stomas were due to cancer. The mean QOL score of the participants was 4.13 ± 1.07. The ostomates scored relatively well in both physical (5.68 ± 1.76) and spiritual (4.32 ± 1.36) domains, but the sociological (2.85 ± 1.3) domain score was very low. Permanent ostomates scored significantly higher than the temporary ostomates (P = 0.04). CONCLUSION: The QOL score of ostomates was less than the scores reported in the Western population and living with stoma significantly alters their lifestyle. Therefore, follow-up services and counseling services to the ostomates by the health-care professionals are needed.
Trend in Prevalence of Hepatitis B Virus Infection Among Blood Donor Individuals: An Eleven-year of Experience in Lorestan, Iran

Background: Hepatitis B virus is one of the transfusion transmissible infections. Despite the availability of hepatitis B virus (HBV) vaccine and screening tests but still danger of virus transmission via blood transfusion is high in some regions. The objective of this study was to determine the trend of seroprevalence of hepatitis B in over an 11-year period (2005–2015). Methods: In this study, 355,083 blood donors were estimated for hepatitis B surface antigen (HBs Ag) seropositivity during 2005–2015 who referred to blood infusion centers of Lorestan province. Third-generation ELISA method was used to detect HBs Ag. Results: The prevalence of HBs Ag in blood donors was 0.29% (1017). It was decreased steadily from 2005 to 2015 (0.68% to 0.12%) but increased in 2008 year. The trend prevalence of HBs Ag seropositivity significantly decreased over the study period (P < 0.001). The decline in HBV infection rates was more prominent in regular and repeated donor's groups compared to people who donated blood for the first time (P < 0.001). Conclusions: The result of present study was indicated, Lorestan city in west of Iran can be classified as a low-income region because the low prevalence of HBs Ag in blood donors. Also the prevalence of HBs Ag in first-time donors was higher than other groups.
Preparation of Quasi-Free-Standing Graphene with a Super Large Interlayer Distance by Methane Intercalation

Preparation of high quality graphene with uniform layers currently remains a bottleneck. In particular, graphene with only one large-sized monolayer is very difficult to obtain. With epitaxial growth of graphene under a hydrogen atmosphere and high temperature, even as high as 1550 °C, the obtained graphene was intercalated by methane and methyl group (−CH3) species. Spontaneously, this intercalation makes the coupling of adjacent layers weak and leads to each layer behaving like free-standing graphene. X-ray diffraction spectra demonstrate that the interdistance of adjacent layers is abnormally large, disclosing each layer suspended by the intercalation, regardless of the layer number. Our findings have opened a possible route to prepare free-standing, high quality graphene effectively in large-scale, behaving like one monolayer free-standing graphene. The Raman spectra also support this conclusion.
Factor Influences for Diagnosis and Vaccination of Avian Infectious Bronchitis Virus (Gammacoronavirus) in Chickens

Infectious bronchitis virus (IBV) is a major economic problem in commercial chicken farms with acute multiple-system infection, especially in respiratory and urogenital systems. A live-attenuated and killed vaccine is currently immunized to control IBV infection; however, repeated outbreaks occur in both unvaccinated and vaccinated birds due to the choice of inadequate vaccine candidates and continuous emergence of novel infectious bronchitis (IB) variants and failure of vaccination. However, similar clinical signs were shown in different respiratory diseases that are essential to improving the diagnostic assay to detect IBV infections. Various risk factors involved in the failure of IB vaccination, such as various routes of application of vaccination, the interval between vaccinations, and challenge with various possible immunosuppression of birds are reviewed. The review article also highlights and updates factors affecting the diagnosis of IBV disease in the poultry industry with differential diagnosis to find the nature of infections compared with non-IBV diseases. Therefore, it is essential to monitor the common reasons for failed IBV vaccinations with preventive action, and proper diagnostic facilities for identifying the infective stage, leading to earlier control and reduced economic losses from IBV disease.
New Predictive Biomarkers for Ovarian Cancer

Ovarian cancer is the eighth-most common cause of death among women worldwide. In the absence of distinctive symptoms in the early stages, the majority of women are diagnosed in advanced stages of the disease. Surgical debulking and systemic adjuvant chemotherapy remain the mainstays of treatment, with the development of chemoresistance in up to 75% of patients with subsequent poor treatment response and reduced survival. Therefore, there is a critical need to revisit existing, and identify potential biomarkers that could lead to the development of novel and more effective predictors for ovarian cancer diagnosis and prognosis. The capacity of these biomarkers to predict the existence, stages, and associated therapeutic efficacy of ovarian cancer would enable improvements in the early diagnosis and survival of ovarian cancer patients. This review not only highlights current evidence-based ovarian-cancer-specific prognostic and diagnostic biomarkers but also provides an update on various technologies and methods currently used to identify novel biomarkers of ovarian cancer.
Pearson's Hard-Soft Acid-Base Principle as a Means of Interpreting the Reactivity of Carbon Materials

In the current studies we are focusing on the utility of the theory of hard and soft acids and bases (HSAB), as proposed by Pearson, for the description of the reactivity of different types of two-radical graphene sheets where two neighbouring carbon atoms are unsaturated in the zigzag position. The closed- and open-shell systems were taken into account. The well-known theoretical reactivity indices (ionization potential, electron affinity and global softness) were calculated for the adsorbents analyzed. We have shown that the values of these parameters are independent of the size of the carbon models. To test the reactivity of adsorption sites as probe molecules, we have used the chloride anion (Cl−), cation (Cl+) and radical (Cl0), respectively. Respective correlations between the enthalpy of reaction, the ionization and/or electronic chemical potential of the carbon structures were found. The results obtained confirm the original HSAB concept of Pearson which has been improved recently by Nalewajski. A similar relationship was observed for the adsorbent charge-transfer term, i.e. the change in the electron densities of the analyzed graphene sheets before and after the adsorption process. From an analysis of the results presented, it has been deduced that a charge-transfer mechanism is probable for chloride ion/adsorbent complexes. Moreover, the acid–base duality of carbon models during the adsorption process was shown and confirmed.
SAP-SSE: Protecting Search Patterns and Access Patterns in Searchable Symmetric Encryption

Searchable symmetric encryption (SSE) enables users to search over encrypted documents in untrusted clouds without leaking the search keywords to the clouds. Existing SSE schemes achieve high search efficiency at the expense of leaking access patterns and search patterns, where clouds can recover a large percentage of queried keywords using the leaked access patterns and search patterns. To prevent clouds from recovering users’ keywords, researchers have proposed a number of solutions to protect either search patterns or access patterns. However, none of them can protect both access patterns and search patterns. Moreover, existing SSE schemes cannot work in the generic database setting that allows multiple users to write or read over encrypted documents. In this paper, we propose an efficient searchable symmetric encryption scheme, called SAP-SSE, which protects both access patterns and search patterns in the generic database setting. The main idea of protecting search patterns is to leverage re-encryption cryptosystems to shuffle index entries over multiple clouds. To protect access patterns, we distribute secure indexes to multiple clouds and then propose an index redistribution protocol that allows users to renew index entries in clouds. Furthermore, SAP-SSE provides a configurable security policy to balance security and efficiency. Formal security analysis and experimental evaluation show that SAP-SSE can prevent pattern leakage with low overhead.
Occupational Therapists’ Professional Quality of Life

Occupational therapists (OTs) interface patients much longer than other healthcare workers and, thus, are likely to experience a high level of stress because of work, physical fatigue, lack of professional knowledge and skills, and problematic relationships with patients, etc. This study examined the quality of the lives of OTs and the workplace which is an influential factor. This study recruited 200 OTs and used a professional quality of life scale. We found that, only 27.0% experience high levels of compassion satisfaction (CS) and 80.5% and 74.5% experience high or average levels of burnout (BO) and secondary traumatic stress (STS) of compassion fatigue (CF), respectively. We discovered that CS was higher in temporary employees; and CF was higher in females, subjects in their 30s; and those working at general hospitals. Also, BO was higher in those with one to five years of clinical experience and regular employees. Last, STS was higher in the group without stable income. This study verified that clinical experience is a critical factor that reduces BO, and excessive workload outside of treatment lowers the professional quality of life. This suggests that work environment and regulations related to OTs must be improved to increase CS and reduce CF.
Testing for the Environmental Fate and Safety of E-Waste using Nitrobacter and Mice Model

The present study aimed to test for the environmental fate and safety of e-waste using Nitrobacter sp. and mice model assays. The Nitrobacter sp. toxicity test was designed in four treatments and control setups namely 6.25, 12.5, 25, 50 % and control separately in both fresh and marine water for 24 h at 25 °C. The Wister albino mice were separated into three set-ups of 8 animals each (4 females and 4 males) in which 1 ml/kg bw of normal saline which serves as control set-up was orally administered to Group 1 while 500 mg/kg bw doses of Products A and B preparations were administered to Groups 2 and 3, respectively once daily for 14 days at 25 °C. The result revealed higher values of heavy metals in products A and B. Products A and B had the highest and lowest EC50 values of 111.19 % and 922.26 % in fresh and marine water, respectively. The oral administration of 500 mg/kg bw of products A and B resulted in non-significant (P > 0.05) body/tissue weights decrease and increase in the levels of AST, ALT, ALP, urea and creatinine in the biochemical profile of the exposed mice. There were more serious but non-cancerous histopathological injuries to the kidney tissue structures than liver tissue structures. The study demonstrated the possible high toxicity of unregulated disposal of these e-wastes into the environments and animals and therefore recommends proper treatment or recycling of these wastes before disposal. Keywords— E-waste toxicity, mice model, Nitrobacter sp. , pollution, public health monitoring.
GBP5 Serves as a Potential Marker to Predict a Favorable Response in Triple-Negative Breast Cancer Patients Receiving a Taxane-Based Chemotherapy

Pre-operative (neoadjuvant) or post-operative (adjuvant) taxane-based chemotherapy is still commonly used to treat patients with triple-negative breast cancer (TNBC). However, there are still no effective biomarkers used to predict the responsiveness and efficacy of taxane-based chemotherapy in TNBC patients. Here we find that guanylate-binding protein 5 (GBP5), compared to other GBPs, exhibits the strongest prognostic significance in predicting TNBC recurrence and progression. Whereas GBP5 upregulation showed no prognostic significance in non-TNBC patients, a higher GBP5 level predicted a favorable recurrence and progression-free condition in the TNBC cohort. Moreover, we found that GBP5 expression negatively correlated with the 50% inhibitory concentration (IC50) of paclitaxel in a panel of TNBC cell lines. The gene knockdown of GBP5 increased the IC50 of paclitaxel in the tested TNBC cells. In TNBC patients receiving neoadjuvant or adjuvant chemotherapy, a higher GBP5 level strongly predicted a good responsiveness. Computational simulation by the Gene Set Enrichment Analysis program and cell-based assays demonstrated that GBP5 probably enhances the cytotoxic effectiveness of paclitaxel via activating the Akt/mTOR signaling axis and suppressing autophagy formation in TNBC cells. These findings suggest that GBP5 could be a good biomarker to predict a favorable outcome in TNBC patients who decide to receive a taxane-based neoadjuvant or adjuvant therapy.
Disassembly Sequence Planning: A Survey

It is well-recognized that obsolete or discarded products can cause serious environmental pollution if they are poorly be handled. They contain reusable resource that can be recycled and used to generate desired economic benefits. Therefore, performing their efficient disassembly is highly important in green manufacturing and sustainable economic development. Their typical examples are electronic appliances and electromechanical/mechanical products. This paper presents a survey on the state of the art of disassembly sequence planning. It can help new researchers or decision makers to search for the right solution for optimal disassembly planning. It reviews the disassembly theory and methods that are applied for the processing, repair, and maintenance of obsolete/discarded products. This paper discusses the recent progress of disassembly sequencing planning in four major aspects: product disassembly modeling methods, mathematical programming methods, artificial intelligence methods, and uncertainty handling. This survey should stimulate readers to be engaged in the research, development and applications of disassembly and remanufacturing methodologies in the Industry 4.0 era.
High Density Lipoprotein Cholesterol Efflux Capacity and Atherosclerosis in Cardiovascular Disease: Pathophysiological Aspects and Pharmacological Perspectives

Over the years, the relationship between high-density lipoprotein (HDL) and atherosclerosis, initially highlighted by the Framingham study, has been revealed to be extremely complex, due to the multiple HDL functions involved in atheroprotection. Among them, HDL cholesterol efflux capacity (CEC), the ability of HDL to promote cell cholesterol efflux from cells, has emerged as a better predictor of cardiovascular (CV) risk compared to merely plasma HDL-cholesterol (HDL-C) levels. HDL CEC is impaired in many genetic and pathological conditions associated to high CV risk such as dyslipidemia, chronic kidney disease, diabetes, inflammatory and autoimmune diseases, endocrine disorders, etc. The present review describes the current knowledge on HDL CEC modifications in these conditions, focusing on the most recent human studies and on genetic and pathophysiologic aspects. In addition, the most relevant strategies possibly modulating HDL CEC, including lifestyle modifications, as well as nutraceutical and pharmacological interventions, will be discussed. The objective of this review is to help understanding whether, from the current evidence, HDL CEC may be considered as a valid biomarker of CV risk and a potential pharmacological target for novel therapeutic approaches.
Academic procrastination and self-efficacy among a group of dental undergraduate students in Malaysia

BACKGROUND: Undergraduate dental students have to do multiple tasks as part of their extensive curriculum in order to achieve the proficiencies expected of them. During the course of their study, a tendency to procrastinate and question their self-efficacy is detrimental for the students. The aim of this study was to evaluate the level of procrastination and self-efficacy and its related factors among dental undergraduate students. SUBJECTS AND METHODS: This cross-sectional study was conducted among all (n = 361) consented dental undergraduate students of our dental school. A twenty-item Lay's Procrastination Scale for student population and a ten-item General Self-Efficacy Scale were used for the study after getting institutional ethical approval. The quantitative data were explained using descriptive statistics. Independent sample t-test and ANOVA were used to determine the association between self-efficacy, academic procrastination, and genders and academic years. Pearson correlation coefficient was used to determine the association between self-efficacy and procrastination. Multiple linear regression analysis was performed to determine the related factors to academic procrastination. RESULTS: High procrastination (score ≥62) was seen among 28.5% of students. The mean self-efficacy score was 29.5. There was no significant difference between genders for procrastination scores (P = 0.835) and between academic years (P = 0.226). Males showed significantly more self-efficacy (P < 0.001), and self-efficacy did not show any significant difference (P = 0.204) between academic years though a tendency for year 5 students to have lower self-efficacy scores was observed. Academic procrastination was negatively correlated with self-efficacy (r = −0.238 and P < 0.001). CONCLUSIONS: For dental undergraduates who have cognitive load as well as work associated with patients, procrastination and self-efficacy are negatively correlated.
Visualization of micromorphology of petal epidermal features of waxy and velvety flowers in Phalaenopsis

Phalaenopsis, also known as moth orchids, are well known for their use as potted plants and high-grade cut flowers. The flower petals of Phalaenopsis have two specific natural textures, waxy and velvety. In order to look for the factors that affect the flower petal textures, in this study, scanning electron microscopy (SEM) and optical microscopy were used to observed, compared, and analyzed the cell shape and arrangement of petal epidermal cells among seven samples from Orchidaceae family, including six Phalaenopsis cultivars of different colors and optical textures, and one Paphiopedilum sample as the out-group. The observational results revealed that waxy petals were formed by parallel and tight arrangement of flat epidermal cells with relatively thick and smooth cuticles, whereas soft (velvety) petals were formed by independent and loose arrangement of conical epidermal cells with thin cuticles. This research showed that the petal epidermal cell structure and arrangement and the accumulation of cuticles directly affect the petal texture of Phalaenopsis germplasm, but not strongly relate to germplasm sources, floral color, floral stripe color, and floral size. The study could provide basic information for further studies on floral texture formation mechanisms in Phalaenopsis, and could provide more insight and evidence for directional breeding of ornamental traits in orchid.
Removal of Natural Organic Matter from Groundwater Using Advanced Oxidation Processes at a Pilot Scale Drinking Water Treatment Plant in the Central Banat Region (Serbia)

To improve water quality, a pilot-scale evaluation into upgrading the conventional treatment process was conducted. By following DOC content, UV254 absorbance, SUVA and by-products formation, three oxidative pre-treatments were evaluated: pre-ozonation (2.2 g O3/m3); O3/H2O2 process (2.2 g O3/m3; H2O2:O3 = 1:2) and O3/H2O2 process (2.2 g O3/m3; H2O2:O3 = 2:1). The second pre-treatment gave the best results, with a final average DOC content of 0.9 mg C/L, UV254 absorbance of 0.06 cm−1 and the lowest THMFP of 130 μg/L. UV254 absorbance can serve as a proper indicator for predicting THM and HAA formation, yielding a correlation coefficient ≥ 0.90.