Miracle-dz/UniFAR-FTUs huggingface dataset:
Long-Term Application of a Synbiotic Chitosan and Acinetobacter KU011TH Mixture on the Growth Performance, Health Status, and Disease Resistance of Hybrid Catfish (Clarias gariepinus × C. macrocephalus) during Winter

The effects of potential synbiotic chitosan and Acinetobacter KU011TH mixture on growth performance, immune response, and A. hydrophila resistance were investigated for the first time. The control group was fed a basal diet (A), and group B was given the formula B diet that was supplemented with chitosan at 20 mL/kg diet via top dressing. The other synbiotic groups, C, D, and E, were top-dressed with the target probiotics at 1 × 108, 1 × 109, and 1 × 1010 CFU/kg diet, respectively, and coated with the same concentration of chitosan. Fish were continuously fed the five different feeds for 16 weeks during winter. At the end of the trial, the growth parameters of the test groups did not significantly differ from those of the control (p > 0.05). All the symbiotic-chitosan treatments significantly increased various hematological and serum immune parameters. Moreover, the expression levels of immune-related genes were strongly elevated in the head kidney and spleen, whereas upregulated expression was observed in the liver and whole blood (p < 0.05). Survival analysis indicated that fish in groups B and C showed significantly higher survival (84.33 ± 2.21 and 79.50 ± 6.34%) than those in groups A, D and E (55.33 ± 8.82%–74.00 ± 6.50) (p < 0.05) after injection with A. hydrophila for 14 days.
A note on Modeling of Mathematical Competences

In this paper, the authors present causal model of mathematical competences. This paper is a continuation of research on causal models that authors presented at international conferences in Albania (Tepes, Lesin and Hrkac 2013) and the United Arab Emirates (Tepes, Simovic and Tepes 2014). Mathematical competences were grouped in three areas: language/data, geometry and arithmetic. Statistical set in our research consisted of 77 children from kindergarten in Zagreb, Croatia. We have 8 measuring variables for language/data competences, 5 measuring variables for geometry competences and 6 measuring variables for arithmetic competences. Three different models from our previous papers, for language/data, geometry and arithmetic competences, are now combined into a unified causal model of mathematical competences in kindergarten.
PATTERN OF NON-VENEREAL GENITAL DERMATOSES IN ADULT MALE- A CLINICAL STUDY IN A TERTIARY CARE CENTRE

Objectives: Non-venereal genital dermatoses are genital dermatoses that are not sexually transmitted. It causes extreme anxiety in patients because venereal disease is often their primary concern. The aim was to study the clinical pattern of various non-venereal genital dermatoses in males aged 18–60 years. Methods: A cross-sectional clinical study was done among male patients between 18 and 60 years of age with non-venereal genital dermatoses attending the dermatology outpatient department of a tertiary care hospital in Eastern India. Patients clinically diagnosed with non-venereal genital dermatoses were included in the study after signing the informed consent thorough examination of the genital lesion was done with special relevance to the morphology, number, tenderness, regional lymph node involvement, etc. A complete physical and systemic examination was done. Associated skin lesions were noted. Investigations such as blood sugar, Tzanck smear, KOH mount, Gram stain, and histopathological examination were done in relevant cases. At the Venereal Diseases Research Laboratory, HIV tests were done to rule out STDs. Statistical analysis was done using the necessary software. Results: A total of 133 patients were included in the study. The commonest age group was 18–30 years. The most common [35%] disease was Candidal Balano-Posthitis. Married people were more affected. Diseases predominant in rural areas were LSA. Non-STD genital dermatoses are less more common in Muslims. Diabetes is common in both personal and family histories. Conclusion: For the differentiation of non-venereal genital dermatoses, apart from history and investigations, the clinical study such as age, residence, religion, and morphology of the lesions are very important. A clinician should have an unbiased approach towards genital conditions.
The inclusion of critical thinking in an accounting curriculum: Students' perceptions

Employers and professional bodies have called repeatedly for critical thinking to be included in the curricula of higher education courses. Therefore, researchers should actively engage in developing course material that includes critical thinking. The purpose of this paper is to explore students' perceptions of the inclusion of a critical thinking course in an accounting curriculum in order to develop and foster their critical thinking. The study adopted a mixed method design to understand students' perceptions of the inclusion of critical thinking in the accounting course. The findings revealed positive results and the promising perceptions that most students benefitted from the inclusion of the critical thinking in the curriculum. The five highest ranked areas in which students benefitted were communication skills, gaining confidence, writing skills, improved reading, and teamwork skills. In addition, most students confirmed that the critical thinking course assisted them to think logically and clearly and be independent. This study contributes to the improvement of student preparedness and readiness for the workplace and to the acquisition of lifelong skills through formal education.
The Relationship between Credit Volume and Non-performing Loans on Profitability Levels

This study aims to determine the relationship between the volume of credit and the level of profitability and the relationship between non-performing loans and the level of profitability at PT. Bank Rakyat Indonesia (Persero) Tbk. Makassar Ahmad Yani branch was researched for the last 5 (five) years, namely 2010-2014. The analytical method used in this research is the descriptive analysis method, statistical analysis of correlation, and determination using primary data obtained directly from PT. Bank Rakyat Indonesia (Persero), Tbk Makassar Branch Ahmad Yani. Based on the results of research conducted, an increase in the volume of credit tends to increase the profitability of PT. Bank Rakyat Indonesia (Persero), Tbk Makassar Branch Ahmad Yani. Meanwhile, non-performing loans and the level of profitability have a negative relationship. This means that when non-performing loans increase, the level of profitability will be low. On the other hand, when non-performing loans decrease, profitability will increase.
KATRIN "First Light" - Commissioning and Modelling of the Beamline

The Karlsruhe TRitium Neutrino (KATRIN) experiment is the next generation tritium beta-decay experiment to perform a direct and model independent measurement of the effective electron-neutrino mass with an unprecedented sensitivity of 200 meV (90% C.L.). The thesis describes the commissioning and modelling of the entire beamline with a focus on the alignment of the magnetic flux tube that guids the signal electrons. The aim is to demonstrate the required collision-free guidance through the entire KATRIN beamline in order to obtain the statics that are essential for achieving the targeted sensitivity.
History of mathematics (HM) in secondary school mathematics textbook

Abstract The purpose of this study was to investigate elements of the history of mathematics in secondary school mathematics textbooks in Ethiopia. In line with this, the study also identified the extent to which mathematics is seen as a social construct in textbooks. To achieve these four mathematics textbooks from Grades 9 to Grade 12 were selected for this purpose. The document review method used to determine the extent of use of elements of the history of mathematics, the stage in the unit it used, and the learning domains of mathematics it covered in these textbooks are considered. For document analysis purposes Erdoğan et al.’s (2015) classification of elements of the history of mathematics was adopted. This distribution involves historical notes, notes on usage areas of mathematics, applications with historical notes, and historical elements in students’ extracurricular activities. The result has indicated that it has found 26 elements of the history of mathematics and the highest number found in the grade 11 Mathematics textbook. The learning domain algebra in the form of historical notes also received the highest coverage than others. Moreover, the result has indicated most elements of the history of mathematics were used at the beginning stage of the unit. Finally, the study has concluded that elements of the history of mathematics are not sufficiently integrated with the contents of mathematics textbooks. Several elements of the history of mathematics are far from the social context of the learner, as indicated in the textbooks.
THE EFFECT OF THE NUMBER OF DEGREES OF KINEMATIC REDUNDANCY ON THE ACTUATION FORCES OF A PLANAR PARALLEL MANIPULATOR

This paper proposes a two-step optimization procedure for resolving the actuation forces of a kinematically redundant planar parallel manipulator following a specified trajectory. Simulation results compare the performance of the manipulator when different degrees of kinematic redundancy are used. It is seen that the required forces are generally lower when there are more degrees of kinematic redundancy; however, more mechanical energy is required. In some cases, fewer degrees of kinematic redundancy can produce similar results from a force point of view, while requiring less energy. Furthermore, the importance of correctly choosing an initial configuration is presented. The proposed method finds an optimal initial configuration by considering a performance index along the entire trajectory. The evolution of the singularity loci as the manipulator moves along the trajectory demonstrates why certain initial configurations should not be used, even if they are optimal at the initial pose.
The Functional Erythropoetin rs1617640 Gene Polymorphism does not Affect Life Expectancy of Patients with Peripheral Arterial Disease

Background : A common functional variant (c.-1306A > C, rs1617640) in the gene encoding erythropoietin ( EPO ) has been linked to expression of erythropoietin and markers of erythropoiesis. Aim of the current study was the analysis of the role of this polymorphism for long term survival of patients with peripheral arterial disease (PAD). Methods : EPO genotypes as well as biomarkers for erythropoiesis were analyzed in a cohort of 946 patients with PAD. Survival follow-up was performed 20 years af-ter recruitment of patients. Results : Twenty years after recruitment, 752 (79.5%) patients were dead, 103 (10.9%) were still alive, and 91 (9.6%) were lost-to-follow up. In a Cox regression analysis including smoking habit, sex, type-2 diabetes, hypercholesterolemia and arterial hypertension, EPO genotypes were not associated with overall survival (Hazard ratio 0.63; 95% confidence interval 0.88–1.08, p = 0.63). Conclusions : The functional EPO rs1617640 gene polymorphism, irrespective of its association with markers of erythropoiesis, does not affect survival of PAD patients.
FTDN: Multispectral and Hyperspectral Image Fusion With Diverse Temporal Difference Spans

Multispectral (MS)–hyperspectral (HS) image fusion, which aims to enhance the spatial resolution of low-spatial-resolution HS images with a high-spatial-resolution MS, has provided a wide range of applications in remote sensing. However, relatively long revisit cycles of HS satellites and irresistible weather factors cause the acquisition of HS and MS images at the same time difficult. Most of the existing approaches neglect the temporal difference between MS and HS images and perform weakness in the challenging case with diverse temporal difference spans. In this article, we propose a novel image fusion strategy with embedding a stage of feature matching before interaction. On the one hand, we explore the role of spectral correlation modeling between HS and MS images, which accounts for the utilization of available spatial information from MS images. On the other hand, we design a feature aggregation module to fully exploit the nonlinear gaps and dependencies of heterogeneous data and utilize adaptive gains to realize complementary information projection and fusion. We build Dongying (DY) and Yellow River Estuary (YRE) remote-sensing datasets based on Sentinel-2 and ZiYuan (ZY)-1 02D satellites with diverse temporal difference spans. The extensive experiments demonstrate that our method is robust to the span of temporal difference and shows superior performance over the existing methods visually and quantitatively.
Testing the mean in multivariate regression using set-indexed Gaussian white noise

We propose an asymptotic test method for checking the validity of a multivariate spatial regression that utilizes the distribution model of set-indexed Gaussian white noise. The random set function is obtained as the limit of the partial sums of the vector of observations sampled according to a continuous probability measure (design). It is shown under relatively mild condition that the test which is defined as the integral with respect to the partial sums of the observation converges to an optimal test constructed based on the Cameron-Martin density of the multivariate shifted Gaussian white noise. The optimality of the design under which the experiment was performed is also investigated. We also study the application of the established test procedure to a multivariate real data obtained from a mining industry.
Empirical Study of Ricardian Equivalence Hypothesis in Indonesia: The Effect of Budget Deficit on Public Consumption in 1990-2018

Fiscal policy remains a central tool to boost the economy. Indonesia has implemented a deficit fiscal policy for the budget deficit, but Indonesia has not achieved the economic growth target. This reality shows that there is a gap between policy and policy outcomes. This research aims to prove the existence of the Ricardian Equivalence Hypothesis (REH), namely whether the fiscal policy, in this case, the budget deficit, affects public consumption. In addition to analyzing gross domestic product (PDB) as a measure of revenue, government debt, and budget deficits, researchers added variable deposit rates as one of the monetary policy instruments. The research employs Adaptive Expectation Model analysis that shows that in the short and long term, only variable deposit rates had a significant effect on public consumption, meaning that other variables such as GDP, government debt, and budget deficits had no impact on public consumption in Indonesia for 1990-2018 period. Thus, this study validates the existence of Short Ricaermc both in the short and long term. With this result, the government must change the deficit policy strategy so that the results of productive spending can be enjoyed directly by the people. Some policies that should to maintain interest rates, not do too much debt, develop the country's industry, and country's deficit budgets to things that directly support the economy Keywords: fiscal policy, budget deficit, Ricardian Equivalence Hypothesis, public consumption, Adaptive Expectation ModelJEL Clasification : E2, E62, H62
Essential Oils and Their Components Control Behaviour of Yellow Mealworm (Tenebrio molitor) Larvae

Simple Summary This study investigated the use of essential oils (EOs) from different plants to control the behaviour of Tenebrio molitor L. , a pest of grain and flour. Among the EOs tested, spearmint was the most effective repellent for mealworm larvae, followed by clove. East-Indian lemongrass, thymus, lavandin, and eucalyptus EOs showed lower repellent properties. Terpinene-4-ol and carvone, were the most effective repellents, while limonene, myrcene, and γ-terpinene had no significant activity. Abstract Beetle Tenebrio molitor L. (Coleoptera, Tenebrionidae) is a well-known pest of grain and flour in food stores and grocery shops. Recently, commercial cultivation of the insect was started for human food and animal feed. Behaviour control of this insect using natural repellents is promising both for grain protection and commercial cultivation. We analysed if natural products of plant origin, namely essential oils (EOs), could be used for this purpose. Behavioural tests were performed using EOs of six plants: thymus (Thymus vulgaris), eucalyptus (Eucalyptus globulus), spearmint (Mentha spicata), lavandin (Lavandula × hybrida), East-Indian lemongrass (Cymbopogon flexuosus), and clove (Eugenia caryophyllus). The most effective repellent for mealworm larvae was EO of spearmint, moderate activity showed that of clove and the least repellent were EOs of lemongrass thymus and lavandin. EO of eucalyptus caused almost no or very low effect. Six of the most abundant compounds of the EOs were selected for testing. The most effective single compounds were terpinene-4-ol and carvone, low-effective cis-sabinene hydrates and those of no significant activity were limonene, myrcene and γ-terpinene.
Association of the rs17782313, rs17773430 and rs34114122 Polymorphisms of/near MC4R Gene with Obesity-Related Biomarkers in a Spanish Pediatric Cohort

Obesity is a multifactorial disease whose onset and development are shaped by the individual genetic background. The melanocortin 4 receptor gene (MC4R) is involved in the regulation of food intake and energy expenditure. Some of the single nucleotide polymorphisms (SNPs) of this gene are related to obesity and metabolic risk factors. The present study was undertaken to assess the relationship between three polymorphism SNPs, namely, rs17782313, rs17773430 and rs34114122, and obesity and metabolic risk factors. One hundred seventy-eight children with obesity aged between 7 and 16 years were studied to determine anthropometric variables and biochemical and inflammatory parameters. Our results highlight that metabolic risk factors, especially alterations in carbohydrate metabolism, were related to rs17782313. The presence of the minor C allele in the three variants (C–C–C) was significantly associated with anthropometric measures indicative of obesity, such as the body mass and fat mass indexes, and increased the values of insulinemia to 21.91 µIU/mL with respect to the wild type values. Our study suggests that the C–C–C haplotype of the SNPs rs17782313, rs17773430 and rs34114122 of the MC4R gene potentiates metabolic risk factors at early ages in children with obesity.
Factors related to the compliance to consuming iron-folic acid in young women in East Kalimantan, Indonesia

Weekly Iron Folic Acid supplementation/WIFAS program for adolescent girls is an effective strategy for preventing anemia. However, in Indonesia, only 1,4% adhere to taking WIFAS. This study aimed to discover the factors related to adolescent girls’ adherence to consuming WIFAS in East Kalimantan. The design of this study was cross-sectional, using a purposive sampling technique to find a sample of 825 adolescent girls. The research location was the East Kalimantan Provincial Health Office from November 15 to December 15, 2021. The analytical method uses the Chi-Square test and binary logistic regression test. The results showed that the level of adherence to the consumption of iron folic acid for adolescents girl was 17,6%. The factors related to the adherence of adolescent girls in consuming WIFAS in East Kalimantan were the area of residence (p=0,023), hemoglobin check (р=0,0001), access to information on iron-folic acid (p=0,014), received/purchased iron-folic acid (p=0,000), knowledge (p=0,010) and the use of the Cegah Anemia Remaja Indonesia (CERIA) application (р=0,0001). Based on reg log analysis, factors such as having received/purchased iron WIFAS, Hb checks, knowledge, and use of the CERIA application were associated with adolescent girls’ adherence to WIFAS. In conclusion, adolescent girls with regular WIFAS consumption were easier to get WIFA, check Hb, have good knowledge and use the CERIA application. These findings suggest the need to carry out hemoglobin checks on adolescent girls, increase the availability of WIFAS and socialize the use of the CERIA app.
Bioengineered 3D Ovarian Models as Paramount Technology for Female Health Management and Reproduction

Ovarian dysfunction poses significant threats to the health of female individuals. Ovarian failure can lead to infertility due to the lack or inefficient production of fertilizable eggs. In addition, the ovary produces hormones, such as estrogen and progesterone, that play crucial roles not only during pregnancy, but also in maintaining cardiovascular, bone, and cognitive health. Decline in estrogen and progesterone production due to ovarian dysfunction can result in menopausal-associated syndromes and lead to conditions, such as osteoporosis, cardiovascular disease, and Alzheimer’s disease. Recent advances in the design of bioengineered three-dimensional (3D) ovarian models, such as ovarian organoids or artificial ovaries, have made it possible to mimic aspects of the cellular heterogeneity and functional characteristics of the ovary in vitro. These novel technologies are emerging as valuable tools for studying ovarian physiology and pathology and may provide alternatives for fertility preservation. Moreover, they may have the potential to restore aspects of ovarian function, improving the quality of life of the (aging) female population. This review focuses on the state of the art of 3D ovarian platforms, including the latest advances modeling female reproduction, female physiology, ovarian cancer, and drug screening.
Chukrasia tabularis limonoid plays anti-inflammatory role by regulating NF-κB signaling pathway in lipopolysaccharide-induced macrophages

Background Chukrasia tabularisis, a well-known tropical tree native to southeastern China, has anti-inflammatory and antioxidant activities, and contains large amounts of limonoids and triterpenoids. Objective The aim of this study was to investigate the potential anti-inflammatory activity of limonoids from C. tabularis on lipopolysaccharide (LPS)-mediated RAW264.7 cells. Methods and results Using a bioassay-guided approach, the chemical fraction with high anti-inflammatory activity was found and its chemical constituents were investigated. Phytochemical studies on active extracts resulted in the separation of three novel phragmalin limonoids (1–3), together with two known limonoids (4–5) and 11 tirucallane triterpenes (6–16). The activity of these isolated compounds in the production of nitric oxide (NO) on LPS-reated macrophages was evaluated. Limonoid 2 indicated significant anti-inflammatory activities with IC50 value of 4.58 μM. Limonoid 2 notably inhibited the production of NO, interleukin- 6 and tumor necrosis factor-α on macrophage. Signal transduction and activation of STAT and NF-κB activators were effectively blocked by limonoid 2. Conclusions These results indicate that limonoid 2 has an anti-inflammatory effect by the inhibiting JAK2/STAT3, iNOS/eNOS, and NF-κB signaling pathways and regulating inflammatory mediators.