Miracle-dz/UniFAR-FTUs huggingface dataset:
The Role of Organizational Culture in the Implementation of Personal Hygiene

Organisational culture is a system that continues to process in an organizational environment. The culture inherent in the organizational environment requires a long stage to become a thing that binds all elements in the organization. In nursing, organizational culture plays a vital role as a device that regulates the behaviors of nurses in carrying out their responsibilities. One of the most fundamental responsibilities is fulfilling the personal hygiene needs of inpatient clients. The c pandemic to post-pandemic conditions emphasized the need for personal hygiene as one of the essential items for the entire community and inpatient clients in hospitals. Implementing a right on target, effective and efficient personal hygiene is indispensable for a hospital to maintain service quality and increase client satisfaction. The extent to which organisational culture contributes to improving the quality of nursing services in carrying out actions to fulfil personal hygiene needs for clients needs to be investigated further. The results of this study can be a positive input for elements of hospital management to determine the direction of policies related to the implementation of nursing actions to meet the personal hygiene needs of clients. This study uses a qualitative method with a phenomenological approach. Determination of participants using purposive sampling, the number of participants is seven people, and data collection using in-depth interviews. Three themes were identified in this research, namely (1) Support System; (2) Teamwork; (3) Motivation. The effectiveness of the implementation of PH for clients must be distinct from the individual elements of the nurses themselves and the most excellent support from hospital management, both in appealing to and providing the facilities needed to improve service quality. Keywords: Organizational Culture, Personal hygiene, Quality of service
Digital Technologies and Empathy for Students with Special Education Needs

Information and communication technologies (ICTs) have significantly advanced a number of industries during the past few decades. ICTs are now a vital part of the teaching and learning process in many contexts. All social groups, including those with unique educational requirements for children and adults, have received assistance. In this essay, we give a succinct summary of the most pertinent articles for apps used for assessment, intervention, and development of empathy, a critical skill that studies show persons with special educational needs lack. Empathy is a sophisticated sort of psychological inference that draws conclusions about the thoughts and feelings of others by combining observation, memory, information, and reasoning.
3D assimilation and radiative impact assessment of aerosol black carbon over the Indian region using aircraft, balloon, ground-based, and multi-satellite observations

Abstract. A three-dimensional (spatial and vertical) gridded data set of black carbon (BC) aerosols has been developed for the first time over the Indian mainland using data from a dense ground-based network, aircraft- and balloon-based measurements from multiple campaigns, and multi-satellite observations, following statistical assimilation techniques. The assimilated data reveal that the satellite products tend to underestimate (overestimate) the aerosol absorption at lower (higher) altitudes with possible climate implications. The regional maps of BC-induced atmospheric heating derived using this data set capture the elevated aerosol heating layers over the Indian region along with the spatial high over the Indo-Gangetic Plain. It is shown that, over most of the Indian region, the incorporation of realistic profiles of aerosol absorption/extinction coefficients and single scattering albedo into the radiative transfer calculations leads to enhanced high-altitude warming. This could strongly influence the upper-tropospheric and lower-stratospheric processes, including the vertical transport of BC to higher altitudes, and thus have larger implications for atmospheric stability than what would be predicted using satellite observations alone. This will have larger implications for atmospheric stability than what would be predicted using satellite observations alone and could strongly influence the upper-tropospheric and lower-stratospheric processes, including increased vertical transport of BC to higher altitudes. The 3D assimilated BC data set will be helpful in reducing the uncertainty in aerosol radiative effects in climate model simulations over the Indian region.
Factors Influencing Identification as a Fan and Consumerism towards The Virtual K-Pop Group MAVE:

The K-Pop industry has been developing Virtual K-Pop Group, a K-Pop group with virtual human members who are made to be as similar as possible to actual humans. Identification as a fan is one of the important factors in creating a purchasing behavior in the form of consumerism towards certain K-Pop groups. Therefore, this research was conducted with the aim of identifying factors that significantly influence identification as a fan and consumerism towards one of the well-known Virtual K-Pop Groups, which is MAVE:. This research uses an extended Theory of Planned Behavior framework with additional audio and visual components, virtual group concept, peer influence and social media influence as the variables. The method used in this research is quantitative and using a questionnaire with respondents from Indonesia who have at least once performed consumerism towards MAVE: as the data source. The data was analyzed using the Path Analysis method to examine the influence between variables, namely attitude, subjective norms, perceived behavioral control, identification as a MAVE: fan and consumerism towards MAVE:. The result indicates that virtual group concept’s influence towards attitude and peer influence’s influence towards subjective norms are positively significant. Attitude, subjective norms and perceived behavioral control positively significant in influencing identification as a MAVE: fan. Also, identification as a MAVE: fan significantly influences consumerism towards MAVE: positively. The findings of this research is aimed to understand the consumer behavior of Virtual K-Pop Group consumers, so that it becomes the basis for label companies that produce these groups to create effective strategies for generating revenue as the main goal of business.
Otoferlin as a multirole Ca2+ signaling protein: from inner ear synapses to cancer pathways

Humans have six members of the ferlin protein family: dysferlin, myoferlin, otoferlin, fer1L4, fer1L5, and fer1L6. These proteins share common features such as multiple Ca2+-binding C2 domains, FerA domains, and membrane anchoring through their single C-terminal transmembrane domain, and are believed to play a key role in calcium-triggered membrane fusion and vesicle trafficking. Otoferlin plays a crucial role in hearing and vestibular function. In this review, we will discuss how we see otoferlin working as a Ca2+-dependent mechanical sensor regulating synaptic vesicle fusion at the hair cell ribbon synapses. Although otoferlin is also present in the central nervous system, particularly in the cortex and amygdala, its role in brain tissues remains unknown. Mutations in the OTOF gene cause one of the most frequent genetic forms of congenital deafness, DFNB9. These mutations produce severe to profound hearing loss due to a defect in synaptic excitatory glutamatergic transmission between the inner hair cells and the nerve fibers of the auditory nerve. Gene therapy protocols that allow normal rescue expression of otoferlin in hair cells have just started and are currently in pre-clinical phase. In parallel, studies have linked ferlins to cancer through their effect on cell signaling and development, allowing tumors to form and cancer cells to adapt to a hostile environment. Modulation by mechanical forces and Ca2+ signaling are key determinants of the metastatic process. Although ferlins importance in cancer has not been extensively studied, data show that otoferlin expression is significantly associated with survival in specific cancer types, including clear cell and papillary cell renal carcinoma, and urothelial bladder cancer. These findings indicate a role for otoferlin in the carcinogenesis of these tumors, which requires further investigation to confirm and understand its exact role, particularly as it varies by tumor site. Targeting this protein may lead to new cancer therapies.
Dynamics of viscous backflow from a model fracture network

Hydraulic fracturing for production of oil and gas from shale formations releases fluid waste, by-products that must be managed carefully to avoid significant harm to human health and the environment. These fluids are presumed to result from a variety of fracture relaxation processes, and are commonly referred to as ‘flowback’ and ‘produced water’, depending primarily on the time scale of their appearance. Here, a model is presented for investigating the dynamics of backflows caused by the elastic relaxation of a pre-strained medium, namely a single fracture and two model fracture network systems: a single bifurcated channel and its generalization for $n$ bifurcated fracture generations. Early- and late-time asymptotic solutions are obtained for the model problems and agree well with numerical solutions. In the late-time period, the fracture apertures and backflow rates exhibit a time dependence of $t^{-1/3}$ and $t^{-4/3}$ , respectively. In addition, the pressure distributions collapse to universal curves when scaled by the maximum pressure in the system, which we calculate as a function of $n$ . The pressure gradient along the network is steepest near the outlet while the bulk of the network serves as a ‘reservoir’. Fracture networks with larger $n$ are less efficient at evicting fluids, manifested through a longer time required for a given fractional reduction of the initial volume. The developed framework may be useful for informing engineering design and environmental regulations.
INSIGHTS INTO HYDROCARBON CHAIN AND AROMATIC RING FORMATION IN THE INTERSTELLAR MEDIUM: COMPUTATIONAL STUDY OF THE ISOMERS OF AND AND THEIR FORMATION PATHWAYS

Small hydrocarbons such as acetylene is present in circumstellar envelopes of carbon-rich stars, but the processes that yield larger molecules, and eventually polycyclic aromatic hydrocarbons (PAHs), remain poorly understood. To gain additional insight into the early steps of such processes, electronic structure calculations were performed on the potential energy surfaces of , and . The results establish reactive pathways from acetylene and its ion to formation of the first aromatic ring. We characterize the stable isomers, their spectroscopic properties, and many of the transition structures that represent barriers to isomerization. The pathways to stabilized and are most likely to arise from unimolecular decomposition of hot and by H atom elimination. By contrast, we found an ion-molecule pathway to to be very stable to fragmentation and elimination reactions even without collisional stabilization. This aromatic species is a good nucleation center for the growth of larger PAHs in interstellar conditions.
Radiation chemistry of H 2O + O 2 ices

The chemistry and spectroscopy of proton-irradiated H2O + O2 ices have been investigated in relation to the production of oxidants in icy satellite surfaces. Hydrogen peroxide (H2O2), ozone (O3), and the hydroperoxy (HO2) and hydrogen trioxide (HO3) radicals have all been observed, and their temperature and dose dependent production trends have been measured. We find that O2 aggregates form during the growth of H2O + O2 ice films, and the presence of these aggregates greatly affects the HO2 and H2O2 yields. In addition, we have found that the position of the spectral maximum of the ν3 vibration of O3 shifts with ice composition, giving an indication of the degree of dispersion of O3 molecules within the ice. We discuss the relevance of these measurements to icy satellite surfaces. © 2007 Elsevier Inc. All rights reserved.
Pre‐Vegetation, Single‐Thread Rivers Sustained by Cohesive, Fine‐Grained Bank Sediments: Mesoproterozoic Stoer Group, NW Scotland

A Silurian shift in fluvial stratigraphic architecture, coincident with the appearance of terrestrial vegetation in the fossil record, is traditionally cited as evidence for exclusively shallow, braided planforms in pre‐vegetation rivers. While recent recognition of deep, single‐thread channels in pre‐Silurian strata challenge this paradigm, it is unclear how these rivers maintained stable banks. Here, we reconstruct paleohydraulics and channel planform from fluvial cross‐strata of the 1.2 Ga Stoer Group. These deposits are consistent with deep (4–7 m), low‐sloping rivers (2.7 × 10−4 to 4.5 × 10−5), similar in morphometry to modern single‐thread rivers. We show that reconstructed bank shear stresses approximate the cohesion provided by sand‐mud mixtures with 30%–45% mud—consistent with Stoer floodplain facies composition. These results indicate that sediment cohesion from mud alone could have fostered deep, single‐thread, pre‐vegetation rivers. We suggest that the Silurian stratigraphic shift could mark a kinematic change in channel migration rate rather than a diversification of planform.
Assessment of the E3C corpus for the recognition of disorders in clinical texts

Disorder named entity recognition (DNER) is a fundamental task of biomedical natural language processing, which has attracted plenty of attention. This task consists in extracting named entities of disorders such as diseases, symptoms, and pathological functions from unstructured text. The European Clinical Case Corpus (E3C) is a freely available multilingual corpus (English, French, Italian, Spanish, and Basque) of semantically annotated clinical case texts. The entities of type disorder in the clinical cases are annotated at both mention and concept level. At mention -level, the annotation identifies the entity text spans, for example, abdominal pain. At concept level, the entity text spans are associated with their concept identifiers in Unified Medical Language System, for example, C0000737. This corpus can be exploited as a benchmark for training and assessing information extraction systems. Within the context of the present work, multiple experiments have been conducted in order to test the appropriateness of the mention-level annotation of the E3C corpus for training DNER models. In these experiments, traditional machine learning models like conditional random fields and more recent multilingual pre-trained models based on deep learning were compared with standard baselines. With regard to the multilingual pre-trained models, they were fine-tuned (i) on each language of the corpus to test per-language performance, (ii) on all languages to test multilingual learning, and (iii) on all languages except the target language to test cross-lingual transfer learning. Results show the appropriateness of the E3C corpus for training a system capable of mining disorder entities from clinical case texts. Researchers can use these results as the baselines for this corpus to compare their own models. The implemented models have been made available through the European Language Grid platform for quick and easy access.
Interrupting Dissociation of Players through Real-Time Digital Tasks during Online Gambling

Online gambling is relatively easier to access compared to traditional one, so it can pose specific risks to individuals such as causing isolation, lack of interruption and dissociation. Intermittent interactions that require cognitive process can interrupt a task and capture the attentional focus which can help to break the dissociative state of players while playing. This study proposes an approach of using digital tasks to interrupt the dissociation of players during online gambling. We investigated the effectiveness of the approach through mixed methods where participants ( N ¼ 50) were invited to the computerised lab experiment and randomised to five conditions. Participants received digital tasks as an interruption while playing online slot gambling and their response time to the interruptions was measured. After the play, participants completed the Jacob ’ s Dissociation Questionnaire, and the Acceptability Questionnaire (both Likert scale and open-ended questions). The analysis revealed that there was a significant main effect of the inter-ruptions in terms of response times, and a significant interaction between the interruptions and the digital tasks. Five main themes were generated after Thematic Analysis of the qualitative data: (1) Distraction, (2) Awareness, (3) User experience, (4) Considerations for design and (5) Considerations for technology. Digital tasks could be potentially useful tools to interrupt players ’ dissociation during online gambling and support behavioural awareness and change towards more conscious and responsible gambling.
Vortical structures in the near wake of tabs with various geometries

The vortical structures and turbulence statistics in the near wake of rectangular, trapezoidal, triangular and ellipsoidal tabs were experimentally studied in a refractive-index-matching channel. The tabs share the same bulk dimensions, including a 17 mm height, a 28 mm base width and a $24.5^{\circ }$ inclination angle. Measurements were performed at two Reynolds numbers based on the tab height, $Re_{h}\simeq 2000$ (laminar incoming flow) and 13 000 (turbulent incoming flow). Three-dimensional, three-component particle image velocimetry (PIV) was used to study the mean flow distribution and dominant large-scale vortices, while complementary high-spatial-resolution planar PIV measurements were used to quantify high-order statistics. Instantaneous three-dimensional fields revealed the coexistence of a coherent counter-rotating vortex pair (CVP) and hairpin structures. The CVP and hairpin vortices (the primary structures) exhibit distinctive characteristics and strength across $Re_{h}$ and tab geometries. The CVP is coherently present in the mean flow field and grows in strength over a significantly longer distance at the low $Re_{h}$ due to the lower turbulence levels and the delayed shedding of the hairpin vortices. These features at the low $Re_{h}$ are associated with the presence of Kelvin–Helmholtz instability that develops over three tab heights downstream of the trailing edge. Moreover, a secondary CVP with an opposite sense of rotation resides below the primary one for the four tabs at the low $Re_{h}$ . The interaction between the hairpin structures and the primary CVP is experimentally measured in three dimensions and shows complex coexistence. Although the CVP undergoes deformation and splitting at times, it maintains its presence and leads to significant mean spanwise and wall-normal flows.
Clinicopathological characteristics and treatment outcomes of oesophageal cancer patients in Uganda

Background Oesophageal cancer is the seventh most common cancer and the sixth leading cause of cancer death worldwide, and its incidence varies globally. In Uganda, the incidence and trend are on the increase. However, there is a paucity of published data regarding this population’s oesophageal cancer clinicopathologic characterisation and treatment outcomes. Objectives To study the patients’ clinicopathologic characteristics and treatment outcomes of oesophageal cancer over 10 years at the Uganda Cancer Institute. Methods Patients’ charts with histologically confirmed diagnoses of oesophageal cancer for 2009–2019 were identified. Case information, which included patient demographics, history of alcohol use or smoking, tumour location, histological type, tumour grade, clinical TNM (Tumour, Node, Metastasis) staging treatment exposure and treatment outcomes, was evaluated retrospectively. The median survival time was estimated with the Kaplan-Meier method and the median follow-up period was estimated using the reverse Kaplan-Meier. Results 1,965 oesophageal cancer patients were identified; 1,380(70.23%) were males and 585(29.77 %) females, their mean age was 60.20 years (±12.66). Most males had a history of both alcohol consumption and smoking 640(46.38%). The lower third of the oesophagus was the most common anatomical location 771(39.24%). The majority had squamous cell carcinoma histological type 1,783(90.74%) followed by adenocarcinomas 182(9.26%) in the distal oesophagus. Poorly differentiated tumour grade 743(37.81%) was predominant. The majority of the patients were in stage IVB, 733(37.30%), and most patients were planned for the best supportive care, 731(37.20%). Radiation alone was offered to 621(31.60%) and feeding gastrostomy to 249(12.70%). Treatment outcomes: at the time of the current analysis, 58.68% had died, 1.48% were alive and 39.84% were lost to follow-up. The median follow-up period was 65 months (IQR:35.83–83.30) with a median survival time of 4.47 months (95% CI: 4.17–4.80). Conclusion Treatment outcomes of Ugandan oesophageal cancer patients seeking care are poor as most patients present with advanced disease. There is a significant loss of follow-up after treatment initiation. Therefore, reduction in exposure to known modifiable risk factors, early detection and timely referral for treatment strategies are needed to improve outcomes of these patients in our population. Designing interventions to improve treatment adherence is necessary.
Regulation of specific abnormal calcium signals in the hippocampal CA1 and primary cortex M1 alleviates the progression of temporal lobe epilepsy

Temporal lobe epilepsy is a multifactorial neurological dysfunction syndrome that is refractory, resistant to antiepileptic drugs, and has a high recurrence rate. The pathogenesis of temporal lobe epilepsy is complex and is not fully understood. Intracellular calcium dynamics have been implicated in temporal lobe epilepsy. However, the effect of fluctuating calcium activity in CA1 pyramidal neurons on temporal lobe epilepsy is unknown, and no longitudinal studies have investigated calcium activity in pyramidal neurons in the hippocampal CA1 and primary motor cortex M1 of freely moving mice. In this study, we used a multi-channel fiber photometry system to continuously record calcium signals in CA1 and M1 during the temporal lobe epilepsy process. We found that calcium signals varied according to the grade of temporal lobe epilepsy episodes. In particular, cortical spreading depression, which has recently been frequently used to represent the continuously and substantially increased calcium signals, was found to correspond to complex and severe behavioral characteristics of temporal lobe epilepsy ranging from grade II to grade V. However, vigorous calcium oscillations and highly synchronized calcium signals in CA1 and M1 were strongly related to convulsive motor seizures. Chemogenetic inhibition of pyramidal neurons in CA1 significantly attenuated the amplitudes of the calcium signals corresponding to grade I episodes. In addition, the latency of cortical spreading depression was prolonged, and the above-mentioned abnormal calcium signals in CA1 and M1 were also significantly reduced. Intriguingly, it was possible to rescue the altered intracellular calcium dynamics. Via simultaneous analysis of calcium signals and epileptic behaviors, we found that the progression of temporal lobe epilepsy was alleviated when specific calcium signals were reduced, and that the end-point behaviors of temporal lobe epilepsy were improved. Our results indicate that the calcium dynamic between CA1 and M1 may reflect specific epileptic behaviors corresponding to different grades. Furthermore, the selective regulation of abnormal calcium signals in CA1 pyramidal neurons appears to effectively alleviate temporal lobe epilepsy, thereby providing a potential molecular mechanism for a new temporal lobe epilepsy diagnosis and treatment strategy.