Miracle-dz/UniFAR-FTUs huggingface dataset:
Verification analysis for the reliable analytical multi-taper detector in next generation network

Multi-taper method (MTM) acts as an effective detector of spectrum sensing in Cognitive radio networks. In this paper, an analytical study was proposed in which reliable, simple, and computationally efficient mathematical terms for the mean and variance of the probability density function (PDF) were derived using the MTM technique. The closed-form expressions for the probability of detection and false alarm for the MTM detector were obtained accordingly. The proposed analytical study was evaluated by intensive simulations using MATLAB. Different simulation techniques were proposed to verify the derived analysis. The existence of White Gaussian Noise was assumed. Important aspects of spectrum detection in cognitive radio networks were included such as, receiver operating characteristics, detection rate versus signal to noise ratio (SNR), and the minimum desired sample points for a specific performance. A comparison was completed with the energy detection technique and all of the results suggested that the proposed paradigm is both credible and powerful under all the parameters considered in the simulation.
Functional Dyspepsia (FD); Prevalence and Relationship with Psychological Disorders among Medical Sciences Students

The educational environment of medical sciences creates multiple stressful situations; also, psychological disorders are one of causes that are considered for FD. Therefore, this study conducted to investigate the prevalence and relationship of FD with psychological disorders among medical sciences students. This cross-sectional study was conducted on 630 medical sciences students in 2015. Selected participants were evaluated for FD by a general practitioner according to ROME III criteria, and psychological disorders of students were evaluated by a clinical psychologist by using the General Health Questionnaire (GHQ-28). Out of all participants, 120 (20%) participants suffered from FD. There was no significant difference between the two different groups on variables such as age (p=0.546), sex (p=0.751), marital status (p=0.878), residence (p=0.113), GPA (p=0.080), and years of education (p=0.463) as far as FD was concerned. But, there was a significant difference between the different fields on frequency of FD (p=0.012). Participants with FD had significantly higher frequencies of general mental disorder (p= 0.017), somatic symptoms (p= 0.017), anxiety (p= 0.000), social dysfunction (p= 0.003) and depression (p= 0.007). The prevalence of FD among students was above the average prevalence in general population; these results might be due to the youngness of our study population and high frequency of psychological stress in medical training environments. Also, frequency of psychological disorders in FD patients was notably higher than healthy individuals.
Global proteome response of human cancer cell lines to low dose eIF4E/eIF4G inhibition

Cachexia is a debilitating muscle wasting disease and co-morbidity strongly associated with chronic inflammatory conditions such as cancer, chronic heart failure, chronic obstructive pulmonary disease and sepsis. Cachexia has a strong negative impact on quality of life and research suggests that 20% of cancer patients will die of cachexia. Translation initiation is the most highly regulated step of protein synthesis and the eukaryotic initiation factor 4F (eIF4F) translation initiation complex is the gatekeeper of this process; the eIF4F complex is composed of eIFG, a scaffolding protein, eIF4E, an mRNA cap-recognition protein and eIF4A, an RNA helicase. Inhibition of eIF4A by pateamine A has been shown to rescue muscle wasting in vitro and in vivo, this result has been reproduced with other eIF4A inhibitors. Pateamine A is a sponge-derived natural product with nanomolar toxicity to cancer cells. Surprisingly, at doses well below its anti-neoplastic activity it exerts distinct effects on cachexia. The research in this thesis follows on from previous work in our laboratory with pateamine A in human cell lines. Work on the effects of pateamine A on the proteome suggests that not all the proteins changing in expression are explainable by stressing the translation initiation complex. A model by which motifs in the 5’ UTRs of transcripts are a recognised and removed from the system in a selective manner could help explain these effects. We aimed to target eIF4E, another component of the eIF4F system, with two compounds to see if a comparable dose of eIF4E inhibitors could elicit a pateamine-like response. DMSO, a solvent used extensively in this thesis, had unexpected effects on translation. We conclude that 4E1RCat, a compound developed as a selective inhibitor of eIF4E, is not likely to be useable in further work, due to its window of activity coinciding with an unacceptable concentration of DMSO. Ribavirin, our second compound, showed a proteomic response consistent with its classification as an eIF4E translation initiation inhibitor. The proteome response seen with our eIF4E inhibitors is consistent with disruption of translation initiation. However, the data for 4E1RCat was deemed untrustworthy in the wake of revelations that DMSO, the vehicle in which it is dissolved, exerts an almost identical response. From the results obtained, it was not possible to confidently test whether protein downregulation occurred in response to a 5’UTR sequence motif, as seen for inhibitors of eIF4A. Coupled with the uncertainty associated with the 4E1Rcat results, there were relatively few downregulated proteins from the treatments, and many of these could be explained by the direct biological response to the function of the compound in the treatment. All in all, we have obtained new insights into the effects of DMSO on the proteome which will aid further experimentation. This thesis has laid the groundwork for further investigation of the effects of eIF4F inhibition in the context of better understanding the remediation of cachexia through the eIF4F system.
Automatic segmentation of glioblastoma for radiation therapy treatment planning

During the radiation therapy (RT) process, the treatment is planned and simulated with a treatment planning system (TPS): the organs at risk (OAR) and the tumor target are identified and contoured, and the RT dose, delivered by the planned photon beams, is obtained for optimization of the resulting plan. The contouring work-up of tumor target identifies the Planning Treatment Volume (PTV), i.e. the physical RT treatment volume. PTV of glioblastomas (GB) includes, after expansion, Gross Tumor Volume (GTV, the tumor) and Clinical Target Volume (CTV, tumor plus edema). Usually, GTV contouring is performed manually. In this work, we used GlioCAD, a Computer-Assisted Detection software for automatic contouring of gliomas in MRI/DTI, to delineate GTV. The dataset included the images of 21 patients undergoing RT for GB. For each patient, we co-registered CT-planning images and diagnostic MRI (16 T1-gad, 6 T2 Flair, 13 Flair Fat Sat), which were used for GlioCAD training and validation. CAD outlined the tumor with good accuracy, after ruling out some false positives in post-processing. We identified GTVs, suitable for RT requirements. An evolution of GlioCAD will take into account edema for outlining CTV. The method seems promising. A further automatic system for the delineation of sites at risk in the brain is under development, which may be helpful for standardization of RT-treatment planning.
Methylenetetrahydrofolate reductase gene polymorphism and clinical importance in epilepsy patients using valproic acid, carbamazepine and levetiracetam

Abstract Background: We aim to determine the relationships among vitamin B12, folic acid, homocysteine (Hcy), and methylenetetrahydrofolatereductase (MTHFR) C677T polymorphism, as well as the clinical importance of these relationships, in patients using valproic acid (VPA), carbamazepine (CBZ), and levetiracetam (LEV) as monotherapy and polytherapy. Methods: We enrolled 37 patients on VPA, 30 on CBZ, 31 on LEV, 30 on multidrug therapy, and 60 control subjects. We compared the levels of vitamin B12, folic acid, Hcy and polymorphism. Results: Vitamin B12 was low in patients on CBZ (p=0.02) and in combined CBZ and VPA (p=0.02). B12 was low in combined CBZ and VPA (p=0.05). In patients without polymorphism, Hcy was high on VPA (p=0.02), and folic acid was the low on CBZ (0.005). In patients with polymorphism, vitamin B12 was low on CBZ (p=0.02), and folic acid was low on VPA (p=0.04). Vitamin B12 was low in combined CBZ and VPA (p=0.05). Conclusions: Vitamin B12 therapy is necessary on CBZ and on combined CBZ and VPA. VPA should not be used in the presence of other thrombophilic risk factors because of hyperhomocysteinemia. Polytherapy does not increase hyperhomocysteinemia risk in comparison to monotherapy. Vitamin B12, folic acid, Hcy do not effect on seizure frequency.
Design and Realization of a Low Cross-Polarization Conical Horn With Thin Metasurface Walls

A Ku -band low cross-polarization conical horn based on thin metasurface (MTS) walls is presented in this article, along with the relevant design method. The necessary boundary conditions are realized by printing a tensor MTS on the internal walls of the horn, which yields a radiation performance similar to a standard corrugated Gaussian horn yet with the benefits of thin walls. The design method is based on the adiabatic approximate solution for the hybrid mode of a conical waveguide with generic balanced impedance walls, which allows the determination of the impedance profile supporting a single balanced mode. The impedance design is based on the usual locally flat approximation of the wall and on the assumption of plane wave incidence. This approach results in an analytic design method that requires no optimization. The design has been first validated by solving the problem with homogenized impedance boundary conditions through a body of revolution (BoR) method of moments. The actual structure, including impedance wall implementation, is then simulated in full detail with a full-wave fast code. Finally, the horn has been realized and experimentally characterized; measurements show excellent agreement both with theory and with simulations, with a cross-polarization level below −20 dB over a 2 GHz bandwidth.
Impact of maternal stress on outcome of new born

Maternal stress is exposure of an expectant mother to stress, which can be caused by stressful life events or by environmental hardships. The prenatal period is a crucial time for neurodevelopment of fetus. Prenatal period is a vulnerable during which a range of exposures will exert long term changes on brain development. It is very important to manage the stress level of a pregnant mother. Since ancient time it believed that emotional stress of mother affect outcome of new born. Maternal stress during pregnancy can have both immediate and long-term effects on her offspring’s.
Correlation of BMI and MUAC with anemia among Sindh University Students, Jamshoro, Pakistan

Anemia remains the problem of concern world wide, particularly in the developing countries. Anemia is prevalent in all age groups, being more common in female adolescents, and young adults. Number of studies suggests higher prevalence of anemia in University Going students, however, little is known about prevalence of anemia in university students of Pakistan. This cross sectional study was carried out at University of Sindh from January 2016 to December 2016. Total 391 students both male and female students participated in the study. Data was obtained through structured questionnaire. Hematological parameters were assessed using blood analyzer. Overall prevalence of anemia in both male and female students was 53%. The prevalence of anemia was higher in female (80.37%) students than in male students (33.77%). Further, we have found very strong correlation of BMI with MUAC both in male (r=0.83) and female students (r=0.86). We have also found the significant correlation of BMI (r = 0.38, P < 0.05) and MUAC (r = 0.14, < 0.05) with hemoglobin in female students. However, no significant correlation of BMI and MUAC with hemoglobin was observed in male students.In conclusion, higher prevalence of anemia was found in female students, and significant correlation of BMI and MUAC with hemoglobin was found in female students.
Designing Digital Resourcing

Digital innovation has become imperative for organizational survival and is increasingly contributing to the growth of national wealth. A central element of digital innovation, brought into light in this dissertation, is digital resourcing. Digital resourcing refers to actions managing digital resources in the discovery stage of the digital innovation process. The increased awareness of efficient resource management has spurred organizations to search for operational digital resourcing systems that can support their innovation effort. However, there is a lack of existing purposeful digital resourcing systems corresponding to the contemporary ideals serving the requirements of practitioners. This is problematic because it hampers human actors in service ecosystems from mobilizing, decoupling, and pairing digital resources that can leverage sustainable competitive advantages. The problem addressed has provided the momentum to concentrate the research effort into one single research question: How should digital resourcing systems be designed to spur the discovery of digital innovations? Consequently, the purpose of this study has been to identify design knowledge supporting the development of digital resourcing systems, and, to provide an operational digital resourcing system supporting organizations in the discovery stage of the digital innovation process. The main theoretical contribution corresponds to three abstraction levels of design knowledge: 1) an operational web-based digital resourcing system, 2) design principles, and finally, 3) an IS design theory for digital resourcing. The results show that the design knowledge works, provides utility for its purpose, helps to solve the problem, and is correct.
ORAL C.ALBICANS COLONIZATION AND NON-CANDIDA ALBICANS CANDIDA COLONIZATION AMONG UNIVERSITY STUDENTS, YEMEN

Candida albicans is diploid yeast that in some circumstances may cause oral or oropharyngeal infections. This investigation aimed to study the oral C. albicans colonization (OCC) and Non-Candida albicans Candida colonization (ONCACC) and risk factors of OCC in healthy University students. This cross sectional laboratory study was carried between January 2014 and July 2014. A total of 265 healthy students were included in this study, 131 males and 134 females. Demographic and clinical and risk factor variables were registered in predesigned questionnaire. Standard methods were used for collection oral specimens, culturing and identifying Candida species. The crude rate of OCC was 17.7% and the crude rate of ONCACC was 29.1%. C.tropicalisand C.glabrata were the most common species isolated after C . albicans. Statistically significant association of OCC (< 0.05), was identified between the gender (male) (OR = 3.7), smoking (OR = 14.6), denture wearing (OR = 6.2), dental bridge (OR =5.4), orthodontics (OR = 2.5), the reduced saliva flow rate (OR = 11.3), previous antibiotics users (OR=2.99), and Qat chewers (OR = 5.2). Our results are important for the development of strategies to eliminate these indicators of risk and significantly reduce Candida species colonization and oral Candida infections in young healthy adults and in general in Yemen community. The data also suggests that the prevalence rate of OCC was relatively high and it was affected by presence of prostheses, orthodontics, behaviors, xerostomia certain sociodemographic characteristics, which indicate the need for comprehensive, scheduled programs of healthcare educations.
Students’ Use of Information and Communication Technology (ICT) in the Faculty of Allied Medical Sciences, University of Calabar, Nigeria

Background: This study was meant to evaluate the knowledge and utilization of information and communication technology (ICT) resources by students in the Faculty of Allied Medical Sciences, University of Calabar and recommend possible reforms to enhance knowledge and use of ICT by the students. Methods: A 31-item questionnaire was developed to evaluate the knowledge and use of ICT by students in the Faculty of Allied Medical Sciences, University of Calabar. The questionnaire was administered to 240 students in the Faculty through random sampling after it was tested for validity. Data obtained were evaluated in terms of percentages and simple differences. Results: About 88 (40%) students had good knowledge of ICT while the remaining 132 (60%) did not have good ICT knowledge and were not trained previously. It was also discovered that all the Departments in the Faculty of Allied Medical Sciences did not have adequate ICT facilities. The results also showed that few students in the Faculty use ICT facilities for assignment, research and updating lecture notes while most students (n=194, 88.18%), use the available ICT facilities mainly for social networking and recreation. Conclusion: ICT use by students in the Allied Medical Sciences faculty, University of Calabar, is low due to inadequacy of the ICT facilities and lack of training and competence. Keywords: COMPETENCE, STUDENT, KNOWLEDGE, UTILIZATION, ICT, RESEARCH
Can employee workplace mindfulness counteract the indirect effects of customer incivility on proactive service performance through work engagement? A moderated mediation model

ABSTRACT Customer incivility is widespread in service industries, inevitable as employees offer service to a broad range of customers from diverse backgrounds. Stress caused by rude customers depletes front-line employees’ personal resources and develops to adverse work-related outcomes. Workplace mindfulness may provide resources to reduce the detrimental effect of customer incivility on work engagement. Furthermore, drawing from the conservation of resource theory(COR) and job demands-resouces (JD-R) model, this study investigates how work engagement mediates between customer incivility and employee proactive service performance among casino employees. The findings support that workplace mindfulness buffers the relationship between customer incivility and work engagement. Customer incivility is negatively associated with proactive service performance through work engagement. Theoretical and research implications and practical suggestions are proposed.
Distribution and pest status of the Old World screw‐worm fly, Chrysomya bezziana (Diptera: Calliphoridae), in Papua New Guinea and the threat to Australian livestock and wildlife

The distribution of the Old World screw‐worm fly Chrysomya bezziana Villeneuve and the incidence of traumatic myiases (strikes) in livestock, humans and wild animals in Papua New Guinea (PNG) for the period 1973–1985 is described as a foundation for current considerations of risk to Australia. Field studies indicated myiasis caused by C. bezziana occurred throughout PNG to an altitude of 2590 m. Cattle and sheep were the most commonly recorded hosts. The impact of strikes on individual cattle properties varied from negligible levels to every animal being infested on average each year. The incidence of strikes was apparently related to vegetation cover with fewer strikes in open grassland and more strikes in wooded areas. There was no statistical correlation between rainfall and strike incidence although most properties reported that the number of strikes by C. bezziana was greatest after periods of rain. On a mixed‐breed sheep property in the highlands, Romneys suffered an annual strike rate of 20% compared with 9% in Perendales and 7% in Corriedales. The majority of strikes in sheep were in the vulva and anus region (59% of total). Repeated vulva strike in ewes resulted in reduced fertility such that annual lambing rates were reduced by 66% after three strikes and no lambs were produced after five consecutive strikes. Management practices such as dehorning, castration, tail docking and ear tagging frequently resulted in strikes. Deaths of livestock attributed directly to myiases from C. bezziana infestations were common. The incidence of C. bezziana infestations in wildlife and humans in PNG is documented. The results are discussed in relation to risks of its entry to Australia and potential impact of C. bezziana on the livestock industries and wildlife if C. bezziana was accidentally introduced and became established. The implications of predicted climate change on the potential distribution and hosts in Australia are also examined.
Assessing Trust and Intention to Continue Using Internet Banking Through Security Dimension Impact: A Partial Least Squares Analysis

Internet banking is gaining popularity in Malaysia due to its convenience which is achieved by unique business interactions between banking institutions and customers via websites and mobile applications. Based on the past studies, this article developed a research framework to gauge the impact of security dimensions on customer's trust towards intention to continue using Internet banking. By testing the framework using a sample of 163 internet banking users, this study offers significant insights into the potential confidentiality dimensions has significant influence on customer's trust towards intention to continue using Internet banking. The findings revealed that although there was an insignificant relationship between authentication, data integrity and non-repudiation dimension towards customer trust might be the user think that confidentiality was most important factor that contribute to customer's trust level. Consequently, this study presents and supports the important role of trust as a considerable determinant of intention to continue using Internet banking.
Subprime Borrowers, Securitization and the Transmission of Business Cycles

A growing literature (i.e. Jaffee, Lynch, Richardson, and Van Nieuwerburgh 2009, Acharya and Schnabl 2009) argues that securitization improves financial stability if the securitized assets are held by capital market participants, rather than financial intermediaries. I construct a quantitative macroeconomic model with a novel specification for mortgage-backed securities (MBS) to evaluate this claim. My findings suggest that the existence of the securitization market stabilizes the economy under the condition that financial intermediaries do not engage in the acquisition of securitized assets. In the presence of large negative housing preference shocks, the drop in output in the first year after the shock is halved, if subprime MBS are purchased by non-financial agents, rather than held by banks. (Less)