Miracle-dz/UniFAR-FTUs huggingface dataset:
Near-IR integral field spectroscopy of ionizing stars and young stellar objects on the borders of H II regions

Aims. We study three Galactic H II regions - RCW 79, RCW 82, and RCW 120 - where triggered star formation is taking place. Two stellar populations are observed: the ionizing stars of each H II region and young stellar objects on their borders. Our goal is to show that they represent two distinct populations, as expected from successive star-forming events. Methods. We use near-infrared integral field spectroscopy obtained with SINFONI on the VLT to make a spectral classification. We derived the stellar and wind properties of the ionizing stars using atmosphere models computed with the code CMFGEN. The young stellar objects were classified according to their K-band spectra. In combination with published near and mid infrared photometry, we constrained their nature. Linemaps were constructed to study the geometry of their close environment. Results. We identify the ionizing stars of each region. RCW 79 is dominated by a cluster of a dozen O stars, identified for the first time by our observations. RCW 82 and RCW 120 are ionized by two and one O star, respectively. All ionizing stars are early-to-late O stars, close to the main sequence. The cluster ionizing RCW 79 formed 2.3 ± 0.5 Myr ago. Similar ages are estimated, albeit with a larger uncertainty, for the ionizing stars of the other two regions. The total mass-loss rate and ionizing flux is derived for each region. In RCW 79, where the richest cluster of ionizing stars is found, the mechanical wind luminosity represents only 0.1% of the ionizing luminosity, questioning the influence of stellar winds on the dynamics of these three H II regions. The young stellar objects show four main types of spectral features: H 2 emission, Brγ emission, CO bandheads emission, and CO bandheads absorption. These features are typical of young stellar objects surrounded by disks and/or envelopes, confirming that star formation is taking place on the borders of the three H II regions. The radial velocities of most YSOs are consistent with that of the ionized gas, firmly establishing their association with the H II regions. Exceptions are found in RCW 120 where differences up to 50 km s -1 are observed. Outflows are detected in a few YSOs. All YSOs have moderate-to-strong near-IR excess. In the [24] versus K-[24] diagram, the majority of the sources dominated by H 2 emission lines stand out as redder and brighter than the rest of the YSOs. The quantitative analysis of their spectra indicates that, for most of them, the H 2 emission is essentially thermal and likely produced by shocks. We tentatively propose that they represent an earlier phase of evolution compared to sources dominated by Brγ and CO bandheads. We suggest that they still possess a dense envelope in which jets or winds create shocks. The other YSOs have partly lost their envelopes and show signatures of accretion disks. Overall, the YSOs show distinct spectroscopic signatures compared to the ionizing sources, confirming the presence of two stellar populations.
Search for transient neutrino sources with IceCube

The IceCube detector, which is embedded in the glacial ice at the geographic South Pole, is the first neutrino telescope to comprise a volume of one cubic kilometer. The search for neutrinos of astrophysical origin is among the primary goals of IceCube. Point source candidates include Galactic objects such as supernova remnants (SNRs) as well as extragalactic objects such as Active Galactic Nuclei (AGN) and Gamma-Ray Bursts (GRBs). Offline and online searches for transient sources like GRBs and supernovae (SNe) are presented. Triggered searches use satellite measurements from Fermi, SWIFT and Konus. Complementary to the triggered offline search, an online neutrino multiplet selection allows IceCube to trigger a network of optical telescopes, which can then identify a possible electromagnetic counterpart. This allows to probe for mildly relativistic jets in SNe and hence to reveal the connection between GRBs, SNe and relativistic jets. Results from IceCube's triggered GRB search and a first limit on relativistic jets in SNe from the optical follow-up program are presented.
Implementation of food education in school environments improves pupils’ eating patterns and social participation in school dining

Abstract Objective: Schools can be an effective arena for food education. The Tasty School is a tailored teacher-driven food education model that provides tools for implementing food education in primary schools. This study aimed to investigate the effects of the Tasty School model on pupils’ eating patterns and experiences. We also aimed to assess the implementation strength of the Tasty School. Design: A quasi-experimental study was conducted during one school year 2019–2020 in fifteen intervention and ten control schools. The intervention schools implemented the Tasty School food education model. The pupils completed web-based baseline and follow-up questionnaires in class during a school day. The principals were interviewed after the intervention. The data were analysed using a mixed-effects model for repeated measures, accounting for the implementation strength and selected standardisation effects. Setting: A total of twenty-five general Finnish primary schools. Participants: 1480 pupils from grades 3−6 (age 8–12 years) from five municipalities in Finland. Results: Percentages of pupils eating a balanced school meal increased in schools where food education was actively implemented (P = 0·027). In addition, pupils’ experience of social participation in school dining strengthened in schools where the Tasty School model was implemented (5-point scale mean from 2·41 to 2·61; P = 0·017). Conclusions: Healthy eating patterns can be promoted by the active implementation of food education in primary schools. The Tasty School model offers a promising tool for developing healthy eating patterns and increasing social participation among pupils not only in Finland, but also potentially in other countries as well.
The Formation and Evolution of Star Clusters in Interacting Galaxies

Observations of globular clusters show that they have universal lognormal mass functions with a characteristic peak at , but the origin of this peaked distribution is highly debated. Here we investigate the formation and evolution of star clusters (SCs) in interacting galaxies using high-resolution hydrodynamical simulations performed with two different codes in order to mitigate numerical artifacts. We find that massive SCs in the range of form preferentially in the highly shocked regions produced by galaxy interactions. The nascent cluster-forming clouds have high gas pressures in the range of , which is times higher than the typical pressure of the interstellar medium but consistent with recent observations of a pre-super-SC cloud in the Antennae Galaxies. Furthermore, these massive SCs have quasi-lognormal initial mass functions with a peak around . The number of clusters declines with time due to destructive processes, but the shape and the peak of the mass functions do not change significantly during the course of galaxy collisions. Our results suggest that gas-rich galaxy mergers may provide a favorable environment for the formation of massive SCs such as globular clusters, and that the lognormal mass functions and the unique peak may originate from the extreme high-pressure conditions of the birth clouds and may survive the dynamical evolution.
Spatial variation of changes in test–retest reliability of functional connectivity after global signal regression: The effect of considering hemodynamic delay

Global signal regression (GSR) is a controversial analysis method, since its removal of signal has been observed to reduce the reliability of functional connectivity estimates. Here, we used test–retest reliability to characterize potential differences in spatial patterns between conventional, static GSR (sGSR) and a novel dynamic form of GSR (dGSR). In contrast with sGSR, dGSR models the global signal at a time delay to correct for blood arrival time. Thus, dGSR accounts for greater variation in global signal, removes blood‐flow‐related nuisance signal, and leaves higher quality neuronal signal remaining. We used intraclass correlation coefficients (ICCs) to estimate the reliability of functional connectivity in 462 healthy controls from the Human Connectome Project. We tested across two factors: denoising method used (control, sGSR, and dGSR), and interacquisition interval (between days, or within session while varying phase encoding direction). Reliability was estimated regionally to identify topographic patterns for each condition. sGSR and dGSR provided global reductions in reliability compared with the non‐GSR control. Test–retest reliability was highest in the frontoparietal and default mode regions, and lowest in sensorimotor cortex for all conditions. dGSR provides more effective denoising in regions where both strategies greatly reduce reliability. Both GSR methods substantially reduced test–retest reliability, which was most evident in brain regions that had low reliability prior to denoising. These findings suggest that reliability of interregional correlation is likely inflated by the global signal, which is thought to primarily reflect dynamic blood flow.
Circulating T Cell Subsets and ILC2s are Altered in Patients With Chronic Rhinosinusitis With Nasal Polyps After Dupilumab Treatment

Background Chronic rhinosinusitis with nasal polyps (CRSwNP) is mainly associated with type 2 inflammation and is often unmanageable, regardless of the treatment. Dupilumab, a monoclonal antibody targeting the interleukin (IL)-4 receptor alpha to inhibit IL-4 and IL-13 signaling, has recently been shown to significantly improve the condition of patients with CRSwNP. However, the mechanisms underlying this response to dupilumab are not yet fully understood. Objective We sought to examine whether circulating T cell subset proportions and their functions are altered by dupilumab treatment. Methods We first investigated the proportion of circulating T cell subsets and group 2 innate immune cells (ILC2s) in patients with CRSwNP treated with dupilumab using mass and flow cytometry. We then assessed cytokine gene expression and cytokine production in peripheral blood mononuclear cells (PBMCs) using quantitative reverse transcription polymerase chain reaction (RT-PCR) and enzyme-linked immunosorbent assay (ELISA). Results The type 2 T helper (Th2) cell proportion significantly decreased after dupilumab treatment, whereas that of type 1 T helper (Th1) cells increased. Moreover, programmed death-1 (PD-1) expression in regulatory T (Treg) cells was significantly reduced. The proportion of ILC2s significantly increased after dupilumab treatment. Unfortunately, neither cytokine gene expression nor cytokine production in PBMCs showed significant changes. Conclusions Our findings suggest that in CRSwNP patients treated with dupilumab, Th2, Treg, and ILC2 cells, which regulate type 2 inflammation, are modulated in the peripheral circulation. Further analysis of circulating immune cells could provide novel insights into understanding the pathophysiologic mechanisms of dupilumab and the development of tailored therapeutic strategies for patients with CRSwNP.
Connections with totally skew-symmetric torsion and nearly-Kähler geometry

We study almost Hermitian structures admitting a Hermitian connexion with totally skew-symmetric torsion or equivalently, those almost Hermitian structures with totally skew-symmetric Nijenhuis tensor. We investigate up to what extent the Nijenhuis tensor fails to be parallel with respect to the characteristic connexion. This is naturally described by means of an extension of the notion of Killing form to almost Hermitian geometry. In this context, we also make an essentially self-contained survey of nearly-Kaehler geometry, but from the perspective of non-integrable holonomy systems.
Islet‐specific CD8 + T cells gain effector function in the gut lymphoid tissues via bystander activation not molecular mimicry

Type 1 diabetes (T1D) is caused by aberrant activation of autoreactive T cells specific for the islet beta cells. How islet‐specific T cells evade tolerance to become effector T cells is unknown, but it is believed that an altered gut microbiota plays a role. Possible mechanisms include bystander activation of autoreactive T cells in the gut or “molecular mimicry” from cross‐reactivity between gut microbiota‐derived peptides and islet‐derived epitopes. To investigate these mechanisms, we use two islet‐specific CD8+ T cell clones and the non‐obese diabetic mouse model of type 1 diabetes. Both insulin‐specific G9C8 cells and IGRP‐specific 8.3 cells underwent early activation and proliferation in the pancreatic draining lymph nodes but not in the Peyer's patches or mesenteric lymph nodes. Mutation of the endogenous epitope for G9C8 cells abolished their CD69 upregulation and proliferation, ruling out G9C8 cell activation by a gut microbiota derived peptide and molecular mimicry. However, previously activated islet‐specific effector memory cells but not naïve cells migrated into the Peyer's patches where they increased their cytotoxic function. Oral delivery of butyrate, a microbiota derived anti‐inflammatory metabolite, reduced IGRP‐specific cytotoxic function. Thus, while initial activation of islet‐specific CD8+ T cells occurred in the pancreatic lymph nodes, activated cells trafficked through the gut lymphoid tissues where they gained additional effector function via non‐specific bystander activation influenced by the gut microbiota.
Globally Conservative, Hybrid Self-Adjoint Angular Flux and Least-Squares Method Compatible with Voids

In this paper, we derive a method for the second-order form of the transport equation that is both globally conservative and compatible with voids using the continuous finite element method. The main idea is to use the least-squares (LS) form of the transport equation in the void regions and the self-adjoint angular flux (SAAF) form elsewhere. While the SAAF formulation is globally conservative, the LS formulation needs correction in voids. The price to pay for this fix is the loss of symmetry of the bilinear form. We first derive this conservative LS (CLS) formulation in a void. Second, we combine the SAAF and CLS forms and end up with an hybrid SAAF-CLS method having the desired properties. We show that extending the theory to near-void regions is a minor complication and can be done without affecting the global conservation of the scheme. Being angular discretization-agnostic, this method can be applied to both discrete ordinates (SN) and spherical harmonics (PN) methods. However, since a globally conservative and void-compatible second-order form already exists for SN [Wang et al., Nucl. Sci. Eng., Vol. 176, p. 201 (2014)] but not for PN, we focus most of our attention on the latter angular discretization. We implement and test our method in Rattlesnake within the Multiphysics Object Oriented Simulation Environment (MOOSE) framework. The results are also compared to those of other methods.
Dynamical 3-Space Gravity Theory: E ects on Polytropic Solar Models

Numerous experiments and observations have confirmed the existence of a dynamical 3-space, detectable directly by light-speed anisotropy experiments, and indirectly by means of novel gravitational e ects, such as bore hole g anomalies, predictable black hole masses, flat spiral-galaxy rotation curves, and the expansion of the universe, all without dark matter and dark energy. The dynamics for this 3-space follows from a unique generalisation of Newtonian gravity, once that is cast into a velocity formalism. This new theory of gravity is applied to the solar model of the sun to compute new density, pressure and temperature profiles, using polytrope modelling of the equation of state for the matter. These results should be applied to a re-analysis of solar neutrino production, and to stellar evolution in general. It has been discovered that Newton’s theory of gravity [1] missed a significant dynamical process, and a uniquely determined generalisation to include this process has resulted in the explanation of numerous gravitational anomalies, such as bore hole g anomalies, predictable black hole masses, flat spiral-galaxy rotation curves, and the expansion of the universe, all without dark matter and dark energy [2‐4]. This theory of gravity arises from the dynamical 3-space, described by a dynamical velocity field, when the Schr¨ odinger equation is generalised to take account of the propagation of quantum matter in the dynamical 3-space. So gravity is now an emergent phenomenon, together with the equivalence principle. The dynamical 3-space has been directly observed using various light-speed anisotropy experiments, dating from the 1st detection by Michelson and Morley in 1887 [5,6], giving a speed in excess of 300 km/s, after re-calibrating the gas-mode interferometer for actual length contraction e ects, to the latest using spacecraft earth-flyby Doppler shift data [7]. Overall these experiments reveal that relativistic e ects are caused by the absolute motion of rods and clocks wrt the dynamical 3-space, essentially Lorentzian Relativity (LR), rather than the Special Relativity (SR) formalism, which has recently been shown by means of an exact change of space and time variables, to be equivalent to Galilean Relativity [8]. Here we apply the new gravity theory to the internal dynamics of the sun, and compute new density, pressure and temperature profiles, using the polytrope model for the equation of state of the matter. These results should then be applied to a re-analysis of neutrino production [9]. In general the Newtonian-gravity based standard model of stellar evolution also needs re-examination. 2 Dynamical 3-Space
COLOR–MAGNITUDE DISTRIBUTION OF FACE-ON NEARBY GALAXIES IN SLOAN DIGITAL SKY SURVEY DR7

We have analyzed the distributions in the color–magnitude diagram (CMD) of a large sample of face-on galaxies to minimize the effect of dust extinctions on galaxy color. About 300,000 galaxies with log (a/b) < 0.2 and redshift z < 0.2 are selected from the Sloan Digital Sky Survey DR7 catalog. Two methods are employed to investigate the distributions of galaxies in the CMD, including one-dimensional (1D) Gaussian fitting to the distributions in individual magnitude bins and two-dimensional (2D) Gaussian mixture model (GMM) fitting to galaxies as a whole. We find that in the 1D fitting, two Gaussians are not enough to fit galaxies with the excess present between the blue cloud and the red sequence. The fitting to this excess defines the center of the green valley in the local universe to be (u − r)0.1 = −0.121Mr, 0.1 − 0.061. The fraction of blue cloud and red sequence galaxies turns over around Mr, 0.1 ∼ −20.1 mag, corresponding to stellar mass of 3 × 1010 M☉. For the 2D GMM fitting, a total of four Gaussians are required, one for the blue cloud, one for the red sequence, and the additional two for the green valley. The fact that two Gaussians are needed to describe the distributions of galaxies in the green valley is consistent with some models that argue for two different evolutionary paths from the blue cloud to the red sequence.
MAGNETOSPHERIC ACCRETION AND EJECTION OF MATTER IN RESISTIVE MAGNETOHYDRODYNAMIC SIMULATIONS

The ejection of matter in the close vicinity of a young stellar object is investigated, treating the accretion disk as a gravitationally bound reservoir of matter. By solving the resistive MHD equations in two-dimensional axisymmetry using our version of the Zeus-3D code with newly implemented resistivity, we study the effect of magnetic diffusivity in the magnetospheric accretion–ejection mechanism. Physical resistivity was included in the whole computational domain so that reconnection is enabled by the physical as well as the numerical resistivity. We show, for the first time, that quasi-stationary fast ejecta of matter, which we call micro-ejections, of small mass and angular momentum fluxes, can be launched from a purely resistive magnetosphere. They are produced by a combination of pressure gradient and magnetic forces, in the presence of ongoing magnetic reconnection along the boundary layer between the star and the disk, where a current sheet is formed. The mass flux of micro-ejection increases with increasing magnetic field strength and stellar rotation rate, and is not dependent on the disk to corona density ratio and amount of resistivity.
Household characteristics associated with surface contamination of SARS-CoV-2 and frequency of RT-PCR and viral culture positivity–California and Colorado, 2021

While risk of fomite transmission of SARS-CoV-2 is considered low, there is limited environmental data within households. This January—April 2021 investigation describes frequency and types of surfaces positive for SARS-CoV-2 by real-time reverse transcription polymerase chain reaction (RT-PCR) among residences with ≥1 SARS-CoV-2 infection, and associations of household characteristics with surface RT-PCR and viable virus positivity. Of 1232 samples from 124 households, 27.8% (n = 342) were RT-PCR positive with nightstands (44.1%) and pillows (40.9%) most frequently positive. SARS-CoV-2 lineage, documented household transmission, greater number of infected persons, shorter interval between illness onset and sampling, total household symptoms, proportion of infected persons ≤12 years old, and persons exhibiting upper respiratory symptoms or diarrhea were associated with more positive surfaces. Viable virus was isolated from 0.2% (n = 3 samples from one household) of all samples. This investigation suggests that while SARS-CoV-2 on surfaces is common, fomite transmission risk in households is low.
Effects of using immersive virtual reality on time and steps during a locomotor task in young adults

Immersive virtual reality makes possible to perceive and interact in a standardized, reproductible and digital environment, with a wide range of simulated situations possibilities. This study aimed to measure the potential effect of virtual reality on time and number of steps when performing a locomotor task, in a young adult’s population. Sixty young adults (32W, 28M, mean age 21.55 ± 1.32), who had their first immersive virtual reality experience, performed a locomotor task based on "Timed Up and Go" (TUG) task in real, in virtual reality in a stopped train and in virtual reality in a moving train. Time and number of steps variables representing primary locomotion indicators were measured and compared between each condition. Results showed significant increases in time and number of steps in the two virtual reality conditions compared to real but not between the two virtual reality conditions. There was an effect of virtual reality in young adults when performing the locomotor task. It means that technological and digital characteristics of the immersive virtual reality experience led to modify motor strategies employed. Adding a plausible visual optic flow did not appear to affect motor control further when the information is negligible and not essential for performing the task.