Miracle-dz/UniFAR-FTUs huggingface dataset:
Postactivation potentiation: predictors in NCAA Division II varsity track and field power athletes

iv Acknowledgments . v List of Tables . ix List of Figures . x List of Appendices . xi CHAPTER I THE PROBLEM AND ITS SCOPE Introduction . 1 Purpose of the Study . 4 Experimental Hypothesis . 4 Significance of the Study . 5 Limitations . 5 Definitions . 6 CHAPTER II REVIEW OF THE LITERATURE Introduction . 8 Mechanisms . 8 Intramuscular mechanism . 9 Calcium dependent mechanism . 10 Fiber type differences . 10 MLC phosphorylation . 11 MLC phosphorylation pathway . 12 Crossbridge dynamics . 14 Summary . 16 Duration . 16 Inducing Potentiation . 21 vii Measures of PAP . 25 Subject Characteristics Affecting PAP . 27 Complex Training . 30 Prevalence of Use . 32 Conclusion . 33 CHAPTER III METHODS Introduction . 34 Description of Study Population . 34 Design of Study . 34 Data Collection Procedures . 34 Methods of first session . 35 Methods of second session . 36 Statistics . 38 CHAPTER IV RESULTS AND DISCUSSION Introduction . 39 Subject Characteristics . 39 Jump Characteristics . 40 Results . 45 Multiple regression analyses . 45 Mean comparisons . 46 Discussion . 50 Multiple regression analyses . 50 Mean comparisons . 53 Summary . 54
CAVITATING FLOWS IN CENTRIFUGAL IMPELLERS AND THEIR STABILITY ANALYSIS

Cavitating flows in centrifugal impellers are analysed and their stability are discussed based on a closed cavity model to clarify the fundamental characteristics of the flow. For the case with even number of blades, the equal length cavitation becomes statically unstable when it becomes longer than 80% of the blade spacing, where the alternate blade cavitation starts to occur. There are three types of alternate blade cavitation depending on the geometry of the impeller. At a similar cavitation number for alternate blade cavitation, forward and backward rotating cavitations with the number of cells 1, 2 and 3 are found, as well as higher order rotating cavitation modes. Comparisons with experiments are made for two types of rotating cavitation.
Making a change to teachers' readiness of using Assessment for Learning for classroom teaching

Black and Wiliam (1998) and the Assessment Reform Group (1999) point out that if teachers are to raise the quality of students’ learning, they should take Assessment for Learning (AfL) as an essential component of classroom work. However, standards can be raised only if teachers are willing and are able to tackle AfL. Exploration into teachers’ readiness for the new assessment concept indicated that teachers were generally unprepared for AfL. This paper presents an attempt to make a change to the assessment practices in the classroom. The investigation, supported by Quality Education Fund, was conducted in Hong Kong where teaching and learning is deeply influenced by the examination culture (Berry, 2010a in press). This one-year study involved twenty-seven teachers from eight primary schools in Hong Kong. After first being introduced to AfL concepts through a number of seminars and workshops, the teachers tried out some AfL ideas of their choice in their classroom teaching. In their regular teacher community meetings, the teachers shared their experiences and discussed how the AfL practices could be improved. Using lesson observation, document analysis, interviewing and teacher self reflections as the main research instruments, it was found that teachers were more aware of the usefulness of AfL and were more able to use AfL for classroom teaching. There were signs of changes in their classroom assessment practices. Cases will be selected to illustrate the kinds of changes identified in individual teachers.
The role of maternal serum catestatin in the evaluation of preeclampsia and fetal cardiac functions

Objective: To compare the maternal serum catestatin (CST) levels in pregnant women with preeclampsia (PE) and with normal blood pressure and evaluate the relationship between the maternal serum CST levels and fetal cardiac functions. Materials and Methods: This cross-sectional study was conducted on 27 women with early-onset PE (EOPE), 28 women with late-onset PE (LOPE), and 28 healthy pregnant women. Maternal serum CST levels were measured using the enzyme-linked immunosorbent assay kits. Fetal cardiac functions were evaluated using the cardiac Doppler. Results: Maternal serum CST levels were lower in the EOPE group; however, no statistically significant difference was found between the groups. Compared with the other two groups, a statistically significant difference was found in the fetal E/A ratio and myocardial performance index (MPI) values of the EOPE group (p=0.013, p=0.002, p=0.005, p<0.001, respectively). The fetal E/A ratio was positively correlated with the maternal serum CST levels in both the PE and control groups (p<0.001, p<0.001). The fetal isovolumetric relaxation time and MPI values were negatively correlated with maternal serum CST levels in both the PE and control groups (p<0.001, p=0.001, p<0.001, and p=0.002, respectively). Conclusion: Lower CST levels are associated with fetal cardiovascular dysfunction, thus CST can be a critical biochemical marker in fetal cardiac function evaluation.
Relationship between Punitive Discipline and Child-to-Parent Violence: The Moderating Role of the Context and Implementation of Parenting Practices

This study examines the influence of punitive parental discipline on child-to-parent violence (CPV). The moderating roles of parental context (stress and parental ineffectiveness), mode of implementation of parental discipline (parental impulsivity or warmth/support) and the gender of the aggressor in the relationship between punitive discipline and CPV are examined. The study included 1543 university students between 18 and 25 years old (50.2% males, Mage = 19.9 years, SD = 1.9) who retrospectively described their experience between the ages of 12 and 17 years old. The results indicated that stress, ineffectiveness and parental impulsivity increase the negative effect of punitive discipline on CPV. There is no moderating effect of parental warmth/support. The gender of the aggressor is only a moderator in the case of violence toward the father, and the effect of punitive discipline is stronger in males than in females. The study draws conclusions regarding the importance of context and the mode by which parents discipline their children, aspects that can aggravate the adverse effects of physical and psychological punishment on CPV. It is necessary for interventions to focus not only on promoting positive disciplinary strategies but also on the mode in which they are administered and on contextual aspects.
Downstream bandwidth management for emerging DOCSIS-based networks

In this dissertation, we consider the downstream bandwidth management in the context of emerging DOCSIS-based cable networks. The latest DOCSIS 3.1 standard for cable access networks represents a significant change to cable networks. For downstream, the current 6 MHz channel size is replaced by a much larger 192 MHz channel which potentially can provide data rates up to 10 Gbps. Further, the current standard requires equipment to support a relatively new form of active queue management (AQM) referred to as delay-based AQM. Given that more than 50 million households (and climbing) use cable for Internet access, a clear understanding of the impacts of bandwidth management strategies used in these emerging networks is crucial. Further, given the scope of the change provided by emerging cable systems, now is the time to develop and introduce innovative new methods for managing bandwidth. With this motivation, we address research questions pertaining to next generation of cable access networks. The cable industry has had to deal with the problem of a small number of subscribers who utilize the majority of network resources. This problem will grow as access rates increase to gigabits per second. Fundamentally this is a problem on how to manage data flows in a fair manner and provide protection. A well known performance issue in the Internet, referred to as bufferbloat, has received significant attention recently. High throughput network flows need sufficiently large buffer to keep the pipe full and absorb occasional burstiness. Standard practice however has led to equipment offering very large unmanaged buffers that can result in sustained queue levels increasing packet latency. One reason why these problems continue to plague cable access networks is the
The Role of the Gut Microbiota in the Development and Progression of Major Depressive and Bipolar Disorder

A growing number of studies in rodents indicate a connection between the intestinal microbiota and the brain, but comprehensive human data is scarce. Here, we systematically reviewed human studies examining the connection between the intestinal microbiota and major depressive and bipolar disorder. In this review we discuss various changes in bacterial abundance, particularly on low taxonomic levels, in terms of a connection with the pathophysiology of major depressive and bipolar disorder, their use as a diagnostic and treatment response parameter, their health-promoting potential, as well as novel adjunctive treatment options. The diversity of the intestinal microbiota is mostly decreased in depressed subjects. A consistent elevation of phylum Actinobacteria, family Bifidobacteriaceae, and genus Bacteroides, and a reduction of family Ruminococcaceae, genus Faecalibacterium, and genus Roseburia was reported. Probiotics containing Bifidobacterium and/or Lactobacillus spp. seemed to improve depressive symptoms, and novel approaches with different probiotics and synbiotics showed promising results. Comparing twin studies, we report here that already with an elevated risk of developing depression, microbial changes towards a “depression-like” microbiota were found. Overall, these findings highlight the importance of the microbiota and the necessity for a better understanding of its changes contributing to depressive symptoms, potentially leading to new approaches to alleviate depressive symptoms via alterations of the gut microbiota.
Role of innovation ambidexterity in technology startup performance: an empirical study

ABSTRACT Innovation ambidexterity is equivocal and this concept holds a significant position in the literature of strategic entrepreneurship as it binds together the crucial dimensions of organisational learning theory. Ambidexterity is recognised as a source for achieving higher levels of firm performance; however, scholars left a gap in examining how innovation ambidexterity is achieved, particularly so in startups. Therefore, this study investigates how a balance between exploratory and exploitative innovations can lead towards better startup performance under the moderating effects of absorptive capacity and environmental dynamism. This is a cross-sectional empirical research on young incubating technology startups and the data were analysed using partial least square structural equation modelling (PLS-SEM). Our results highlight that innovation ambidexterity plays a crucial role in achieving better startup performance. This research contributes to the ambidexterity literature by providing quantitative evidence at a large scale, delineating the procedure through which entrepreneurs can achieve innovation ambidexterity. The research enriches the organisational learning theory by providing a more inclusive understanding of innovation ambidexterity concept.
Motivation and Intention to Future Donation among Blood Donors Attending a Tertiary Care Hospital Blood Bank in Kerala

Background and Aims: This study aims to identify the level of motivation among blood donors and their intention to donate again and suggest remedial measures to rectify de-motivating influences. Materials and Methods: A self-administered questionnaire was distributed among donors to collect data on variables related to the objective. Results: Most donors were men aged 18-24 years, graduates, and employed. The statistical analysis indicated a significant correlation between socio-demographic variables and intention to donate. Fear is the major de-motivating factor, and waiting hours at the blood bank were rated as inconvenient. Conclusion: Recognition of the positive and negative motivation factors and measures to remove misconceptions of donors will go on a long way in the recruitment and retention of blood donors.
Ovarian cancer ascites induces skeletal muscle wasting in vitro and reflects sarcopenia in patients

Cachexia‐associated skeletal muscle wasting or ‘sarcopenia’ is highly prevalent in ovarian cancer and contributes to poor outcome. Drivers of cachexia‐associated sarcopenia in ovarian cancer remain elusive, underscoring the need for novel and better models to identify tumour factors inducing sarcopenia. We aimed to assess whether factors present in ascites of sarcopenic vs. non‐sarcopenic ovarian cancer patients differentially affect protein metabolism in skeletal muscle cells and to determine if these effects are correlated to cachexia‐related patient characteristics.
Yield, Morphological traits and Nitrogen use Efficiency of Eruca sativa as affected by Irrigation, Plant density and Nitrogen Fertilization

The effect of different levels of irrigation, plant density and N fertilization was studied on the yield, morphological traits and N use efficiency (NUE) of Eruca sativa in the research farm of Islamic Azad University of Birjand, Iran in 2013-2014 in a factorial split-plot experiment. The main plot was devoted to water deficit stress at two levels of no stress (optimum irrigation) and stress at reproductive stage, the sub - plot was devoted to plant density at two levels of 60 and 160 plants m -2 , and thesub-sub-plot was devoted to N fertilization at three rates of 0, 100 and 200 kg ha -1 . It was found that drought stress at reproductive stage resulted in 68.5% loss of seed yield, 66.7 and 73.1% loss of N use efficiency for biomass and seed produ ction as compared to optimum irrigation. In addition, the increase in density from 60 to 160 plants m -2 resulted in 29.5% higher seed yield, 11.5% higher plant height, 30.3 and 21.1% higher NUE for biomass and seed production, 20.3% higher number of auxiliary branches, and 44.9 and 35.7% higher NAE for biomass and seed production. The interaction between plant density and N was significant for NUE for biomass production. Also the interaction between irrigation, plant density and N was significant for seed yield, NUE for biomass and seed production. According to the results, it is recommended to use the dens ity of 160 plants m -2 optimally irrigated and fertilized with 100 kg N ha -1 because of its optimum seed yield and NUE which takes environmental issues under consideration too.
Cryoconcentration by Centrifugation–Filtration: A Simultaneous, Efficient and Innovative Method to Increase Thermosensitive Bioactive Compounds of Aqueous Maqui (Aristotelia chilensis (Mol.) Stuntz) Extract

Maqui (Aristotelia chilensis (Mol.) Stuntz) is a Chilean berry rich in antioxidants, which are mostly found in the pulp and skin of the fruit. The objective was to evaluate the cryoconcentration process by centrifugation–filtration as a simultaneous, efficient, and innovative method to increase the content of thermosensitive bioactive compounds of aqueous maqui extract. Cryoconcentration separated the concentrated solute from the aqueous maqui extract with an efficiency of more than 95%; it increased the content of total polyphenols and total anthocyanins and antioxidant capacity by 280%, 573%, and 226%, respectively. Although the concentrates obtained by evaporation at 50, 70, and 80 °C increased the content of bioactive compounds, they did so in a lower percentage than the cryoconcentrate. Furthermore, cyanidin 3,5-diglucoside was degraded at 70 and 80 °C. In conclusion, cryoconcentration by centrifugation–filtration as a simultaneous process efficiently separates the solutes from the frozen matrix of aqueous maqui extract, and it maintains and increases the contents of polyphenols and anthocyanins and antioxidant capacity. This method is recommended for concentrating natural berry extracts with thermosensitive compounds.
VPrimer: A Method of Designing and Updating Primer and Probe With High Variant Coverage for RNA Virus Detection

Fatal infectious diseases caused by RNA viruses, such as COVID-19, have emerged around the world. RT-PCR is widely employed for virus detection, and its accuracy depends on the primers and probes since RT-PCR can detect a virus only when the primers and probes bind to the target gene of the virus. Most of primer design methods are for a single host and so require a great deal of effort to design for RNA virus detection, including homology tests among the host and all the viruses for the host using BLAST-like tools. Furthermore, they do not consider variant sequences, which are very common in viruses. In this study, we describe VPrimer, a method of designing high-quality primer-probe sets for RNA viruses. VPrimer can find primer-probe sets that cover more than 95% of the variants of a target virus but do not cover any sequences of other viruses or the host. With VPrimer, we found 381,698,582 primer-probe sets for 3,104 RNA viruses. Multiplex PCR assays using the top 2 primer-probe sets suggested by VPrimer usually cover 100% of variants. To address the rapid changes in viral genomes, VPrimer finds the best and up-to-date primer-probe sets incrementally against the most recently reported variants.
Determination of Resting Metabolic Rates in Great Egrets (Ardea alba) and Snowy Egrets (Egretta thula) Using Respirometry

Abstract. Energy enters the body of an animal as food. Some of this energy is then used to satisfy the animal's metabolic functions and various activities. Attempts to quantify energy use and thus determine the costs of these activities often use basal metabolic rate (BMR) or resting metabolic rate (RMR) as an index. These rates occur during periods of minimal and low energy expenditure, respectively. In May 2018, we used respirometry to measure RMR for two Great Egrets (Ardea alba) and three Snowy Egrets (Egretta thula) captured on foraging grounds. The Great Egret mean RMR of 0.015 ml O2/g/min represents the first record for this species. The Snowy Egrets had a mean RMR of 0.021 ml O2/g/min, which was higher than the previously reported BMR. This discrepancy is discussed. Rates for both species were relatively stable over chamber temperatures that ranged between 24°C and 39°C.
Anxiety, depression, self-esteem among children of alcoholic and nonalcoholic parents

Context: Children of alcoholics (COAs) face risks of behavioral problems during childhood and mental health problems in adult life. Identifying these problems at the earliest can significantly reduce the problems in future. Aims: To compare the anxiety, depression, and self-esteem between COA and non-COA parents. Settings and Design: A cross-sectional comparative survey research design was adopted for the present study. The study was conducted at selected government high school located in Bangalore urban. Subjects and Methods: The simple random sampling technique was used. A total of 200 children comprising 100 children of each alcoholic parents and nonalcoholic were recruited for the study. A screening test (modified) was used for identifying COA. Spence Children's Anxiety Scale, Center for Epidemiological Studies Depression Scale for Children (CES-DC), and Rosenberg Self-Esteem Scale were used to assess anxiety, depression, and self-esteem, respectively. Statistical Analysis Used: Data were analyzed using Statistical Package for the Social Sciences software package (version 23). Results: The results show that there is statistically significant difference between COA and non-COA group with regard to anxiety, depression, self-esteem, separation anxiety, social phobia, obsessive compulsive problems, and physical injury. Conclusion: The study concludes that COAs are having higher rate of anxiety, depression, and low self-esteem compared with children of nonalcoholics.
The complete mitochondrial genome of a polyphagous insect: Colasposoma dauricum (Coleoptera: Chrysomelidae: Eumolpinae)

Abstract Colasposoma dauricum Mannerheim, 1849, is an important insect pest distributed in most areas of China. The complete mitochondrial genome of C. dauricum was sequenced and analyzed. The phylogenetic relationships between C. dauricum and other 10 species in the superfamily Chrysomeloidea were reconstructed using maximum likelihood (ML) methods based on the concatenated nucleotide sequences, the phylogenetic analysis showed that C. dauricum is closely related to Basilepta fulvipes in the same subfamily.
JAK3 inhibitors for the treatment of inflammatory and autoimmune diseases: a patent review (2016–present)

ABSTRACT Introduction Up to now, a total of eight Janus kinase (JAK) inhibitors have been approved for the treatment of autoimmune and myeloproliferative disease. The JAK family belongs to the non-receptor tyrosine kinase family, consisting of JAK1, JAK2, JAK3, and Tyk2. Among these four subtypes, only JAK3 is mainly expressed in hematopoietic tissue cells and is exclusively associated with the cytokines shared in the common gamma-chain receptor subunit. Due to its specific tissue distribution and functional characteristics that distinguish it from the other JAKs family subtypes, JAK3 is a promising target for the treatment of autoimmune disease. Areas covered This study aimed to provide a comprehensive review of the available patent literature on JAK-family inhibitors published from 2016 to the present. In addition, an overview of the clinical activities of selective JAK3 inhibitors in recent years was provided. Expert opinion To date, no selective JAK3 inhibitors have been approved for use in clinics. Over the last 5 years, an increasing number of studies on JAK3 inhibitors, particularly ritlecitinib by Pfizer, have demonstrated their promising therapeutic potential. In this review, recent studies reported that selective JAK3 inhibitors may offer valid, interesting, and promising therapeutic potential in inflammatory and autoimmune diseases.
Trends in Sexually Transmitted Infections in United States Ambulatory Care Clinics from 2005–2016

We examined the prevalence trends of non-human immunodeficiency virus (HIV) sexually transmitted infections (STI) and associated patient characteristics in U.S. ambulatory-care settings from 2005–2016. We conducted a retrospective repeated cross-sectional analysis using data from the National Ambulatory Medical Care Survey (NAMCS) for individuals aged 15–64 with a non-HIV STI-related visit. Data were combined into three periods (2005–2008, 2009–2012, and 2013–2016) to obtain reliable estimates. Logistic regression was used for analysis. A total of 19.5 million weighted, non-HIV STI-related ambulatory visits from 2005–2016 were identified. STI-related visits per 100,000 ambulatory care visits increased significantly over the study period: 206 (95% CI = 153–259), 343 (95% CI = 279–407), and 361 (95% CI = 277–446) in 2005–2008, 2009–2012, and 2013–2016, respectively (Ptrend = 0.003). These increases were mainly driven by increases in HPV-related visits (56 to 163 per 100,000 visits) from 2005–2008 to 2009–2012, followed by syphilis- or gonorrhea-related visits (30 to 67 per 100,000 visits) from 2009–2012 to 2013–2016. Higher odds of having STI-related visit were associated with younger age (aged 15–24: aOR = 4.45; 95% CI = 3.19–6.20 and aged 25–44: aOR = 3.59; 95% CI = 2.71–4.77) vs. 45–64-year-olds, Black race (aOR = 2.41; 95% CI = 1.78–3.25) vs. White, and HIV diagnosis (aOR = 10.60; 95% CI = 5.50–20.27) vs. no HIV diagnosis. STI-related office visits increased by over 75% from 2005–2016, and were largely driven by HPV-related STIs and syphilis- or gonorrhea-related STIs.