Miracle-dz/UniFAR-FTUs huggingface dataset:
Evaluation of clinical results after arthroscopic meniscus repair and partial meniscectomy

Aim: The aim of our study was to evaluate the clinical results of arthroscopic repair and partial meniscectomy in the patients who had with meniscal tear. Material and Method: A total of 113 patients who were admitted to our clinic for meniscal tear between 2009 and 2017 were included in our study. Sixty one patients who underwent arthroscopic meniscal repair and 52 underwent partial meniscectomy. All inside meniscal repair technique was used for all meniscal repairs. Clinical assessments included physical examination findings, Lysholm score, the IKDC score and visual analog score(VAS). Barret criteria were used for the clinical assessment of healing status. Results: The patients who underwent meniscal repair, 54 (88.5%) were male 7 (11.5%) were female. The mean age was 32 (1945) years. Our mean follow-up period was 47 (range; 24-109) months. Number of patients underwent only meniscal repair was 29 and concurrent anterior cruciate ligament reconstruction was 32. According to the Barret’s criteria’s patients had 18% surgical failure. The patients who underwent partial meniscectomy33 were male 19 were female. Our mean follow-up period was 29.5 (range; 24101) months. Eight patients (15.4%) had surgical failure. IKDC, Lysholm and VAS scores were statistically significantly improved postoperatively both in repair and partial meniscectomy group Conclusion: Meniscus repair should be performed whenever possible independent from age of patient. When repair is not possible, partial meniscectomy also have good results at least in short term follow-up.
Effects of low pH and raised temperature on egg production, hatching and metabolic rates of a Mediterranean copepod species (Acartia clausi) under oligotrophic conditions.

This study includes the first information on the combined effect of low pH and raised temperature on egg production rate (EP), hatching success (HS), excretion and respiration of the Mediterranean copepod Acartia clausi. Adult individuals of A. clausi and fresh surface seawater were collected at a coastal station in Saronikos Gulf during April 2012. Four different conditions were applied: two different pH levels (present: 8.09 and future: 7.83) at two temperature values (present: 16°C and present+4 °C= 20°C). EP and HS success decreased significantly over the duration of exposure at future pH at both temperature conditions. However, the analysis of the combined effect of pH, T, chlorophyll α and the duration of the experiments on EP and HS revealed that ocean acidification had no discernible effect, whereas warming; food and the duration of exposure were more significant for the reproductive output of A. clausi. Temperature appeared to have a positive effect on respiration and excretion. Acidification had no clear effect on respiration, but a negative effect on the A. clausi excretion was observed. Acidification and warming resulted in the increase of the excretion rate and the increase was higher than that observed by warming only. Our findings showed that a direct effect of ocean acidification on copepod’s vital rates was not obvious, except maybe in the case of excretion. Therefore, the combination of acidification with the ambient oligotrophic conditions and the warming could result in species being less able to allocate resources for coping with multiple stressors.
A Common Metric for Self-Reported Severity of Personality Disorder

Introduction: Dimensional models of personality disorders (PD) in the DSM-5 and ICD-11 share a focus on impairments in self and interpersonal functioning to represent the general features and severity of PD. This new perspective has led to the development of numerous measures for assessing individual differences in PD severity. While this improves choices for researchers and practitioners, it also poses the challenge of an increasing lack of standardization. Objective: The aim of this study is to establish a common metric across 6 widely used self-report measures of PD severity using item response theory models. Methods: 849 participants completed a survey including the Inventory of Personality Organization – 16-item version (IPO-16), the Level of Personality Functioning Scale – Brief Form 2.0, the Level of Personality Functioning Scale – Self-Report, the Operationalized Psychodynamic Diagnosis – Structure Questionnaire Short Form, the Personality Inventory for DSM-5 – Brief Form Plus and the Standardized Assessment of Severity of Personality Disorder (SASPD). We fitted exploratory multidimensional graded response models and used bifactor rotation to extract a general factor across measures. Factor scores were linked to representative T scores using data from a representative survey of 2,502 participants who completed the IPO-16. Results: When using bifactor rotation in a 7-factor model, all items loaded positively on the general factor, and the general factor explained 65.5% of the common variance. With the exception of the SASPD, all measures provided highly discriminating items (factor loadings >0.70) for measuring the general factor and reached an acceptable reliability (>0.80) across a wide range of the latent continuum. We constructed a crosswalk table linking total scores of the 6 measures to each other and to representative T scores. Conclusions: Our results suggest that 6 different self-report measures of the severity of PD capture a strong common factor and can therefore be scaled along a single latent continuum. Our results may facilitate instrument-independent assessment of severity of PD and increase comparability across studies.
ΔNp73β Is Active in Transactivation and Growth Suppression

ABSTRACT p73, a p53 family protein, shares significant sequence homolog and functional similarity with p53. However, unlike p53, p73 has at least seven alternatively spliced isoforms with different carboxyl termini (p73α-η). Moreover, the p73 gene can be transcribed from a cryptic promoter located in intron 3, producing seven more proteins (ΔNp73α-η). ΔNp73, which does not contain the N-terminal activation domain in p73, has been thought to be transcriptionally inactive and dominant negative over p53 or p73. To systemically analyze the activity of the ΔN variant, we generated stable cell lines, which inducibly express ΔNp73α, ΔNp73β, and various ΔNp73β mutants by using the tetracycline-inducible expression system. Surprisingly, we found that ΔNp73β is indeed active in inducing cell cycle arrest and apoptosis. Importantly, we found that, when ΔNp73β is expressed at a physiologically relevant level, it is capable of suppressing cell growth. We then demonstrated that these ΔNp73β activities are not cell type specific. We showed that the 13 unique residues at the N terminus are required for ΔNp73β to suppress cell growth. We also found that, among the 13 residues, residues 6 to 10 are critical to ΔNp73β function. Furthermore, we found that ΔNp73β is capable of inducing some p53 target genes, albeit to a lesser extent than does p73β. Finally, we found that the 13 unique residues, together with the N-terminal PXXP motifs, constitute a novel activation domain. Like ΔNp73β, ΔNp73γ is active in transactivation. However, unlike ΔNp73β, ΔNp73α is inactive in suppressing cell growth. Our data, together with others' previous findings, suggest that ΔNp73β may have distinct functions under certain cellular circumstances.
Ammonia and Inorganic phosphate excretion by zooplankton from inshore waters of the Great Barrier Reef, Queensland. I. Relationship between excretion rates and body size

Ammonia and phosphate excretion rates were measured on various copepods and some ctenophores, siphonophores, decapod larvae, mollusc larvae, polychaete larvae, chaetognaths and appendicularians from inshore waters of the Great Barrier Reef during warm and cold seasons. Regression analyses showed high correlations between the excretion rate and body weight of zooplankton: in the warm season, log yn = 0.518 + 0.525 log x (n = 348. r = 0.612) log yp = -0.174 + 0.429 log x (n=117, r=0.570), and in the cold season, log yn = 0.186 + 0.518 log x (n = 268, r = 0,777) log yp = -1.002 + 0.740 log x (n = 255, r = 0.694), where yn is ammonia excretion (nanograms N per animal per hour), yp is phosphate excretion (nanograms P per animal per hour), x is body dry weight (micrograms per animal); n is the number of measurements, and r is the correlation coefficient. Since the two regression lines for ammonia excretion were parallel a Q10 value of 2.53 was calculated from the results of warm and cold seasons. This calculation was not possible for the phosphate excretion because the regression lines between the seasons were not parallel. The mean ratio of ammonia excretion to phosphate excretion (N:P ratio, by atoms) was 28.56 in the warm season and 24.48 in the cold season. The present results were compared with those of other workers who used zooplankton from different seas, and the effects of experimental conditions, such as injury of specimens, container size, incubation time and feeding on the excretion rates are discussed.
Effectiveness of Splitter Plate in Suppressing the Flow-Induced Vibration of a Circular Cylinder

The effectiveness of splitter plate as suppression device in reducing the flow-induced vibration (FIV) of a circular cylinder was conducted experimentally. The parameter used in this experiment is the gap separation between splitter plate and the circular cylinder (G/D). The control element of gap separations are varied from 0.5 to 2.0. The experiments were conducted in the wind tunnel which was free from external wind conditions at Aeronautical and Wind Engineering Laboratory (AEROLAB), UTM Kuala Lumpur. A supporting structure was designed and fabricated with the purpose to allow free vibration induced by wind on the circular cylinder. The results were analysed through the response of amplitude and power spectral density of the circular cylinder with splitter plate and compared with bare circular cylinder. For the gap separations of G/D = 1.0, 1.5 and 2.0, the vibration of the circular cylinder were successfully suppressed. The optimal distance for gap separation was at G/D = 1.5 with suppression effectiveness of 82%. For G/D = 0.5, on the contrary, the vibration of the circular cylinder was amplified. As conclusion, splitter plate can function to suppress as well as amplify the vibration of cylinder, depending on the gap separation.
Disturbance and growth of juvenile corals {Agaricia humilis and Agaricia agaricites, Scleractinia) in natural habitats on the reef of Curagao

Juvenile coral colonies (diameter C50 mm) of Agaricia humilisand A. agaricjtes (Scleractinia) were studied through time in their natural habitat between 5 and 23 m depth on the fringing reef of C u r a ~ a o (Netherlands Antilles, Caribbean). At 6 censuses (in 1 yr), data were collected on status, morphology and size of juveniles to investigate the following aspects of life histories: frequency of disturbance and mortality, nature of disturbing factors, frequency of fission and fusion processes, and growth during the 5 intervals, as well as annual growth. Absolute linear growth was not dependent on colony size. Maximum linear growth (diameter increase, 80 pm d-l, was potentially equal in both Agaricia species and independent of depth. However, different disturbance levels, related to depth, resulted in a significant difference in actual annual growth in relation to depth zones. A difference in species-specific coral morphology caused a different level of disturbance in the 2 species. In addition there was a negative relation between coral size and mortality in A. humilisjuveniles. Dynamic aspects of the life histories of A. humilis and A. agaricites integrate well with depth-related differences in relative abundance and with differences in reproductive characteristics of the species.
A Molecular Perspective on Lissamphibian Phylogeny

Relationships among the three extant orders of the Class Amphibia were examined using new DNA sequence data from the mitochondrial 12S ribosomal RNA gene. A total of 33 families of amphibians was compared, including representatives of nine of the 10 salamander families, four of the six caecilian families, and 20 of the 22 frog families. Approximately 380 nucleotides were sequenced in each taxon. Of the 333 sites that were aligned and compared for all taxa, 227 were variable. Phylogenetic analyses of these data support the monophyly of the Lissamphibia and the monophyly of each of the three orders, with the Caudata and the Gymnophiona as sister groups. Within the Anura, these molecular data also support the monophyly of the two suborders Archaeobatrachia and Neobatrachia. Although this study represents the broadest sampling of amphibian families at the molecular level, statistical confidence in the relationships must await additional sequence data.
Supporting Young Children's Executive Function Skills through Mindfulness: Implications for School Counselors.

Shifting federal educational priorities and increased funding for pre-K means that more school counselors are interacting with and supporting children before kindergarten age in public school settings. One potential area of focus for school counseling with young students is executive function (EF), including emotional and behavioral regulation, noted in the research literature as essential skills that contribute to later school success. This position paper outlines the importance of EF and implications for school counselors, including using mindfulness as an intervention strategy to enhance young learners’ EF in individual and group contexts as part of a school counseling program.
Investigation of geometric nonlinear stability of sandwich functionally graded (SFGM) spherical shells under uniform external pressure using an analytical approach

Abstract The geometric nonlinear response of spherical shells made of sandwich functionally graded material (SFGM) under uniform external pressure incorporating the effects of transverse shear deformations is considered. The equilibrium and compatibility nonlinear differential equations can be solved by using the modified interaction method. All of the equations are developed based on the first-order shear deformation theory (FSDT). In the present study, the geometric nonlinear problem has been solved for special boundary conditions including movable and fixed clamped supports in the meridional direction. A closed-form nonlinear load-deflection relationship is developed for SFGM shell which expresses the equilibrium path of the shell.
Circadian rhythm of photosynthesis in Kappaphycus alvarezii (Rhodophyta): independence of the cell cycle and possible photosynthetic clock targets

Various processes in the output pathway of the circadian clock are thought to act as important clock targets resulting in the circadian rhythms of photosynthesis observed in various algae. Examples of such processes are synchronization of the cell cycle, pigmentation, and light or dark reaction of photosynthesis. The newly detected, robust photosynthetic circadian rhythm in the red macroalga Kappaphycus alvarezii was investigated in more detail with respect to rhythmically changing components within the photosynthetic apparatus. The following major results were obtained; (1) The growing tips of Kappaphycus (0–2 cm) were found to exhibit a diurnal and circadian rhythm of nuclear division like many other algal species, (2) The circadian photosynthetic rhythm was apparent in the actively growing and dividing tip portions (0–;2 cm) as well as in older portions (2–4 cm) with little remaining mitotic activity. The Kappaphycus rhythm seems therefore to be independent of the cell cycle, at least in the older portions of the thallus, (3) During real (L:D cycle) or subjective (LL) dark phases, net photosynthetic capacity (Pmax) dropped drastically in young (tip) parts of the thallus, and α, the ‘light affinity’ parameter, decreased likewise. The net result of these two changes was an increase in the light saturation point, Ek. Dark respiration did not change rhythmically from one circadian maximum to the next circadian minimum. ΔF/Fm′ dropped during real and subjective night phases, while non-photochemical quenching (NPQ) increased. Low temperature (77 K) emission spectra with an excitation wavelength of 580 nm exhibited a larger increase of the 720:685 nm as well as the 720:696 nm emission quotients compared with spectra at 440 nm excitation for samples harvested in the middle of the subjective dark phase indicating changes in energy trapping from the phycobilisomes to the photosystems.
A comparison of vegetated and unvegetated soft-sediment macrobenthic communities in the River Yealm, south-western Britain

Macrofaunal community structure was examined in a shallow sublittoral sea grass bed (Zostera marina L.) and adjacent unvegetated sediment in the River Yealm, Devon, south-west Britain, on a single sampling occasion in August 1995. The presence of Zostera had a significant influence on macrobenthic community structure in the River Yealm. Samples from inside the sea grass bed were characterized by significantly higher numbers of individuals and species, as well as by greater species richness and high faunal dominance (i.e. low evenness) compared with the unvegetated samples. High faunal dominance within the sea grass bed was attributable to the large numbers of a few species (e.g. the polychaetes juvenile capitellids, Spio filicornis, Exogone hebes, Nereis pelagica and the tanaidacean Apseudes talpa), while increased species richness was a result of a large number of additional rare (1–2 individuals) species. The greatest number of individuals was found in samples with the highest sea grass biomass. Multivariate ordination revealed a distinct separation of macrofauna communities from vegetated and unvegetated sites. Significance testing with ANOSIM shows that there were significant differences in community structure between vegetated and unvegetated habitats.
Beyond Frequency: On the Dictionarization of New Words in Spanish

ABSTRACT:The most recent literature on neology has discussed the criteria that must be taken into account in order to include new words in dictionaries (Metcalf 2002, Ishikawa 2006, O'Donovan and O'Neill 2008, Cook 2010, Freixa 2016, among others). Although there are other factors that must be considered, such as morphologic features and semantic transparency (Adelstein and Freixa 2013, Bernal et al. 2018), authors broadly agree that frequency plays a central role, given that high corpus frequency may be taken as evidence of the institutionalization of a lexical unit. However, it has also been pointed out that frequency is a complex criterion in itself, and, therefore, aspects such as stabilization in use (Cook 2010) or a possible longitudinal change in frequency (Metcalf 2002, Ishikawa 2006) must also be taken into account when measuring frequency in corpora.In this paper, we approach lexical frequency as a criterion to evaluate whether neologisms should be included in Spanish dictionaries from a new perspective. Specifically, we compare data concerning change in frequency of neologisms through time with speakers' perceptions about their novelty, known as "neological feeling" in the specialized literature (Gardin et al. 1974, Sablayrolles 2003). Data about speakers' perceptions is obtained from online questionnaires carried out within the framework of the Neómetro project (Bernal et al. in press). A set of questionnaires was launched in which 100 subjects evaluated their perceptions of 130 neologisms in Spanish according to four different criteria (correct formation, frequency, novelty and necessity of inclusion in dictionaries). Frequency data is taken from an extensive corpus of texts from the press, Factiva, which provides histograms of frequency through time.For this study, we analyze the neologisms that were perceived as the most and the least frequent in the questionnaires. We analyze their frequency curve through time in Factiva to find correlations between stabilization in time and speakers' perceptions of their institutionalization. The data allows us to improve the predictive capacity of frequency as a measure to decide which neologisms should be included in dictionaries, as it introduces factors (formal, semantic or usage) that favor or hinder institutionalization into the equation.
The Formation of Hot Thermal Anomalies in Cold Subduction‐Influenced Regions of Earth's Lowermost Mantle

The Earth's lowermost mantle is characterized by two large low shear velocity provinces (LLSVPs). The regions outside the LLSVPs have been suggested to be strongly influenced by subducted slabs and, therefore, much colder than the LLSVPs. However, localized low‐velocity seismic anomalies have been detected in the subduction‐influenced regions, whose origin remains unclear. Here, three‐dimensional geodynamic calculations are performed, and they show that linear, ridge‐like hot thermal anomalies, or thermal ridges, form in the relatively cold, downwelling regions of the lowermost mantle. Like the formation of Richter rolls due to sublithosphere small‐scale convection (SSC), the thermal ridges form as a result of SSC from the basal thermal boundary layer and they extend in directions parallel to the surrounding mantle flow. The formation of thermal ridges in subduction regions of the lowermost mantle is very sensitive to the thermal structures of the subducted materials, and thermal heterogeneities brought to the bottom of the mantle by subducting slabs greatly promote the formation of thermal ridges. The formation of thermal ridges is also facilitated by the increase of core‐mantle boundary heat flux and vigor of lowermost mantle convection. The thermal ridges may explain the low‐velocity seismic anomalies outside of the LLSVPs in the lowermost mantle. The results suggest that the relatively cold, subduction‐influenced regions of the Earth's lowermost mantle may contain localized hot anomalies.
Secretases as targets for beta‐amyloid lowering drugs

Alzheimer's disease is characterized by the accumulation of neuritic plaques in the brain parenchyma. These plaques contain fibrillar forms of the amyloid β‐peptide (Aβ), which derives from the β‐amyloid precursor protein (βAPP) by proteolytic processing. It is now commonly believed that Aβ plays a crucial role in the pathogenesis of AD, and inhibition of its production is therefore a rational strategy to treat or prevent the disease. Substantial progress has been made in deciphering the molecular mechanisms underlying Alzheimer's disease (AD). In particular, with β‐secretase and the presenilins, two essential factors in the proteolytic generation of Aβ have been identified. Inhibitors of these proteins have already been developed and might serve as lead compounds for Aβ‐lowering drugs of clinical use. Drug Dev. Res. 56, 201–210 2002. © 2002 Wiley‐Liss, Inc.
THE INFLUENCE OF ORGANIZATIONAL COMMITMENT, WORK SATISFACTION, AND ORGANIZATIONAL CULTURE TO BEHAVIOR ORGANIZATIONAL CITIZENSHIP (OCB)

This study intended to determine antecendents and consequences of private university administration employee job satisfaction and Organizational Citizenship Behavior. The background of this study is the issues related to employee who have organizational citizenship behavior who are expected show their best performance and satisfaction. The study was conducted with quantitative methods, using questionnaires with 5 likert scale. The questionnaires were distributed to 220 administration employee from private universities. Respondents had worked for at least two years, permanent employee. This study used convenience random sampling and SEM PLS for data processing purpose. The results showed that organization commitment, organization culture, and satisfaction have positive effect on Organizational Citizenship Behavior. While organization culture does not have any positive effect on on Organizational Citizenship Behavior. Furthermore, job satisfaction has positive effect a on Organizational Citizenship Behavior. The research is expected to provide input for university to manage organizational on Organizational Citizenship Behavior through administration employee job satisfaction