Miracle-dz/UniFAR-FTUs huggingface dataset:
Effects of Roflumilast, Selective PDE4 Inhibitor, on Airway Reactivity in Ovalbumin-Sensitized Guinea Pigs

Abstract Background: Roflumilast as a phosphodiesterase 4 inhibitor has shown to increase lung functions and decrease the number of exacerbations in chronic obstructive lung disease. In this study, its ability to decrease the airway hyperresponsiveness in a model of eosinophil inflammation was evaluated. Methods: Healthy adult male guinea pigs were divided into groups as follows: the first group was considered as a healthy control group (without sensitization and therapy), animals in the second group were sensitized with ovalbumin, but left without further treatment, and the animals in the third group were sensitized with ovalbumin and treated with roflumilast perorally for 7 consecutive days. In vivo airway reactivity was evaluated using double-chamber whole body plethysmograph and measuring the specific airway resistance after nebulization of histamine aerosol. In vitro experiments were performed with tissue strips of trachea and lungs in organ bath, where their contractile responses to cumulative doses of acetylcholine and histamine were registered. The numbers of inflammatory cells in blood and bronchoalveolar lavage fluid were measured using standard staining. Results: Guinea pigs with roflumilast treatment showed decreased in vivo and in vitro airway reactivity associated with suppressed recruitment of inflammatory cells (especially eosinophils) in blood and bronchoalveolar lavage fluid. Conclusion: Roflumilast has demonstrated the therapeutic potential in the model of ovalbumin induced eosinophil inflammation typically present in patients with bronchial asthma.
Evaluation of the predictive value of CHA2DS2-VASc Score for no-reflow phenomenon in patients with ST-segment elevation myocardial infarction who underwent Primary Percutaneous Coronary Intervention

In patients with STEMI, the reason of primary PCI is prompt typical blood stream revert within the infarctrelated artery [1]. Moreover, phenomenon of no-reflow could be a huge challenging drawback of this way. It is characterized as insufficient myocardial flow in spite of physical reviving of the offender injury with PCI . This marvel is associated to more frequency of impacts, briefand long-term mortality rate in patients with STEMI [2].
Parental care and chick growth rate in the Mediterranean Storm-petrel Hydrobates pelagicus melitensis

Abstract – Few studies on parental care in monomorphic seabirds are available, whether or not differences between sexes are reported. We studied the Mediterranean subspecies of Storm-petrel Hydrobates pelagicus melitensis from 2007 through 2012 to determine the nature of parental care for each sex and to evaluate the birds’ breeding behaviour. We found that parents’ investment is equally divided during incubation and first days after hatching. When chicks grow older females invest more time in taking care of their offspring. The variability in parents effort observed in the five years lead us to conclude that parental care changes from year to year is an adaptation to variability in environmental conditions and food availability balancing long lived species vulnerability.
Are Atypical Antipsychotics the Least Detrimental Alternative?

Antipsychotics are typically used for the treatment of schizophrenia, bipolar disorder, and recently, treatment resistant major depressive disorder. A significant, and very concerning, side effect present with first generation antipsychotics is extrapyramidal symptoms, which are disorders of movement. With the advent of atypical antipsychotics, also known as second-generation antipsychotics, these symptoms are purported to be much less frequent and pronounced than they were with the first generation medications. Numerous hypotheses have been proposed as to why atypical antipsychotics produce fewer extrapyramidal symptoms compared to first generation antipsychotics, which this paper will review. Unfortunately, despite the fact that atypicals have reduced extrapyramidal symptoms in those taking antipsychotics, extrapyramidal symptoms are still an unpleasant and potentially dangerous side effect, which can be difficult to detect, and difficult, or even impossible, to treat. Additionally, atypical antipsychotics result in other potentially very serious side effects, specifically and most commonly, metabolic syndrome, which can decrease life expectancy significantly. However, metabolic syndrome, unlike extrapyramidal symptoms, may be preventable in highly motivated and well-supported patients. Thus, this paper concludes that the benefits of the atypical antipsychotics (reduced extrapyramidal symptoms) outweigh the potential risks for the majority of patients.
The weather effect An analysis of individual and institutional investors on Dutch and Spanish markets

This study analyses the effect of weather variables on stock returns on Dutch and Spanish markets. Specifically, number of sunshine hours is examined. Data are collected from both small- and large capital indices per country, representing individual and institutional investors respectively. Using time series regressions, and controlling for different weather variables and seasonal anomalies, no significant relationship is found between number of sunshine hour and stock returns.
WHO Recommendations on Antenatal Care for a Positive Pregnancy Experience: Summary

Approximately 303,000 women and adolescent girls died from pregnancy and childbirthrelated complications in 2015.1 That same year, 2.6 million babies were stillborn. Almost all of the maternal deaths (99%) and child deaths (98%) occurred in lowand middleincome countries. These maternal deaths could have been prevented if the pregnant women or adolescent girls had been able to access quality antenatal care (ANC). 2 Sixty percent of the stillbirths (1.46 million) occurred during the antepartum period and mainly due to untreated maternal infection, hypertension, and poor fetal growth.3
Differences in anthropometric characteristics between young soccer players (U19) members of the best soccer clubs in Montenegro, Bosnia and Herzegovina, and Kosovo

Background and Study Aim: The aim of this research was to determine the differences between the young soccer players (U19) in terms of anthropometric characteristics and body composition. We considered players of three the most successful clubs in three countries of the southern region of the Balkan Peninsula. Material and Methods: The first sub-sample of the subjects was consisted of 17 players of OFC Titograd from Montenegro of the average age 17.12±. 69. The second sub-sample was consisted of 14 players of FC Siroki Brijeg from Bosnia and Herzegovina of the average age of 18.14±. 86. The last sub-sample of the examinees was consisted of 15 players of FC Feronikeli from Kosovo of the average age 18.07±. 46. Anthropometric characteristics in the body composition were evaluated by a battery of 11 variables. The significance of the differences between the young soccer players in the anthropometric characteristics and variables for assessing body composition were determined by ANOVA and LSD Post Hoc test. Results: The young soccer players of the three mentioned clubs have statistically significant differences by the two variables that estimate the upper leg skinfold and fat percentage. The young soccer players of OFC Titograd are significantly better in variable upper leg skinfold than other players. The young soccer players of FC Feronikeli are significantly better in variable fat percentage than players of OFC Titograd. Conclusions: The results can be useful for coaches of other clubs for making a comparison of their soccer players with the young soccer players in this research.
Antibacterial and Antifungal activities of aqueous leaves extract of some medicinal plants

The aqueous leaves extracts of Psidium guajava, Vernonia amygdalina and Azadiracta indica were evaluated for phytochemical compositions, antibacterial and anti-fungi activities against microbial isolates. Ampicillin and vastatin were used as standards for antibacterial and antifungal assays respectively. All phytochemicals tested were present in the aqueous extract of the plants. Glycoside and anthraquinone were absent in methanol extract of P. guajava and A. indica respectively. Psidium guajava recorded the highest alkaloids (6.40±0.35 mg/g) and phenol (18.63±0.29 mg/g) while Azadirachta indica recoded the least. Vernonia amygdalina had the highest saponins (6.63±0.34 mg/g) while Azadirachta indica recoded the least (2.40±0.34 mg/g). However, Azadirachta indica had the highest tannin contents of (23.52±0.25 mg/100g). Aqueous extract of Azadirachta indica had a greater zone of inhibition range between 10.00±0.10 to 14.00±0.05 mm and 13.00±0.05 to 14.00±0.05 mm against bacteria and fungi respectively. Psidium guajava show a lower activity against bacteria (12.00±0.05 mm) and higher antifungal activities (11.00±0.05 mm and 19.00±0.05 mm). Vernonia amygdalina on the other hand had 13.00±1.45 mm zone of inhibition against Streptococcus faecalis and Pseudomonas aeruginosa, and antifungal activities range between 9.00±0.35mm and 15.00±0.45 mm. In conclusion Azadiracta indica extract exhibited more antibacterial activities while Psidium guajava exhibited more antifungal activities than the other plant extracts. Therefore, more research should be carried out to enable the purification of the specific biopotential chemicals from these plants and their subsequent processing into antimicrobial agents in food industries.
A complex assessment of mineral fertilizers with humic substances in an agroecosystem of acid soil

This study aimed to evaluate the impact of total humic extract (THE) and complex mineral fertilizer N5P15K25 enriched with humic substances (HS) 0.5% on moraine loam soil properties and crop productivity. The field experiment was performed in Western Lithuania (55°43ʹ N, 21°27ʹ E) at Vėžaičiai Branch of the Lithuanian Research Centre for Agriculture and Forestry in 2015–2017. Experimental object: THE 16.5%, which contains 13.2% humic acids, 3.3% fulvic acids and 5.5% potassium oxide (K2O), and complex mineral fertilizer N5P15K25 enriched with HS 0.5% consisting of humic and fulvic acids. The soil of the experimental site was moraine loam Bathygleyic Dystric Glossic Retisol. The experiment included the following treatments: 1) unfertilized (control), 2) NPK + THE 20 L ha-1, 3) NPK traditional, 4) NPK 400 kg ha-1 with HS 0.5% and 5) NPK 200 kg ha-1 with HS 0.5%. The experimental data indicated that the application of NPK + THE 20 L ha-1 or complex mineral fertilizers NPK 400 and 200 kg ha-1 with HS 0.5% additives tend to mitigate moraine loam soil acidification and to contribute more to the formation of water-stable aggregates in the topsoil compared with NPK traditional. The both rates of mineral NPK fertilizers enriched with HS 0.5% significantly (by 1.8–2.1 times) increased the content of water-soluble phosphates in the topsoil compared with unfertilized soil. The highest amount of water-extractable organic carbon and the greatest soil biological activity were determined in the soil after incorporation of 400 and 200 kg ha-1 of mineral fertilizers enriched with HS 0.5%. In terms of crop yield, soil enrichment by mineral fertilizers (400 and 200 kg ha-1) with HS 0.5% additives and by the NPK + THE 20 L ha-1 was superior to NPK traditional fertilization.
Exploring EFL teachers’ English language proficiency: Lessons from Indonesia

This paper reports on a study looking at the reading and writing proficiency and vocabulary knowledge of Indonesian EFL teachers, the relationship between proficiency and years of service, and the teachers’ own perceptions of their proficiency in English. Three proficiency tests (Vocabulary Levels Test/VLT, Reading and Writing Tests), questionnaire, and interview were used to collect data. The results point to mixed levels of English language proficiency, negative correlations between years of service and vocabulary, reading and writing test results, and that teachers themselves had difficulties in judging their own English language proficiency. Factors that inhibit the capacity of teachers to focus on their English proficiency are presented. Limitations of the study as well as implications for EFL teachers’ professional development (PD) and future research are also discussed.
The Impact of the Residential Reconstruction Projects on nearby Property Values: A Case of Songpa-gu, Seoul

This study analyzes the impact of housing prices on nearby houses by phase of housing reconstruction. Existing prior studies have analyzed the effect of fundamental changes in neighborhood prices, such as housing redevelopment or ‘New Town’ project. Also, the prior papers related to housing reconstruction did not carry out generalizable analyses, they are based on case studies. This study classified the 16th phase of housing reconstruction into 4th phase through the operational definition. Subsequent steps were followed by an analysis of how residential prices in the neighborhood were affected. The analysis method used a hierarchy-linear hedonic model. This study was analyzed based on the prices of apartments that are common to houses, especially Seoul. Therefore, the model was used to control the effects of the apartment complex. The finding of this study is as follows. 1) The role of the reconstruction apartment stage is different, and the effects of each stage are also different. 2) Depending on the extent of the surrounding neighborhood like neighborhoods in 400m or 800m, the impact of changes in the housing reconstruction is different. 3) Differences in impact are related to the classification of neighboring housing markets. The effect of the sale is different on the basis of the 20 years of construction. This is related to the progress of nearby reconstruction on the grounds that it can determine expectations of possible reconstruction. This may have affected the market with expectations of possible reconstruction and the possibility of replacement by new housing. In the case of Rent Market, the market is affected by physical changes, such as Move-in to apartments where migration demand and reconstruction have been completed as the reconstruction process progresses. However, the study was conducted only on Songpa-gu in Seoul. Therefore, it is difficult to draw up implications for the overall Seoul reconstruction market. Also, it is difficult to derive a clear understanding of whether the peripheral effects of reconstruction are short-term or long-term.
Equality prescribed? Contextual determinants of citizens support for boardroom gender quotas across Europe

We provide the first cross-national comparative study of citizens support for affirmative action policies in the economy using the example of gender quotas for company boards. In contrast to previous studies, we focus on the contextual level and analyse how factors related to political institutions and actors, and economic and social structure, shape citizens support and the gap in support between men and women. We apply multilevel regression analyses of the 2011 Eurobarometer data for 27 European countries. Levels of support, and gender gaps in support for boardroom quotas vary largely between countries. Contextual factors related to gender equality in social and economic life, and societal support for state intervention are the most important determinants of cross-national variation. Citizens endorsement of the quota is low in countries with high levels of gender equality in social and economic life, while support is higher in countries where interventionist policies are widely accepted.
EFFECT OF COBALT ON THE ENVIRONMENT AND LIVING ORGANISMS - A REVIEW

This literature review presents a summary of papers related to the determination of the sources of cobalt compound presence in the environment and the resulting pollution of water and land. Their properties, determining their toxicity to living organisms, have been specified, with sections devoted to their effect on microorganisms and plants. The influence (negative and positive) of cobalt on living organisms in water and soil environments, including the biological balance of the soil (the number of microorganisms, enzymatic activity) and plant growth and development, and the possibilities of their use in the phytoand bioremediation of areas polluted with cobalt have been described. Particular emphasis has been placed on the presentation of the effect of cobalt on animals and man.
THE PENNSYLVANIA STATE UNIVERSITY SCHREYER HONORS COLLEGE DEPARTMENT OF PSYCHOLOGY MOTHERS’ CRITERIA OF CHILD COMPETENCE ACROSS CULTURES

The role of culture in child development remains poorly understood. Differences in parenting practices have been documented, but often the research fails to explain why those differences exist. One reason for differences in parenting practices may be that parents in different cultural contexts have different concepts of what constitutes competence in children. The present study examined cultural differences in maternal conceptions of child competence by using an open-ended format interview, the Criteria of Child Competency (CCC) interview, with mothers from nations that value individuality and independence (Germany, the United States), nations that value communality and interdependence (India, Nepal), and a nation with traditional values of communality and interdependence that is undergoing rapid modernization, which may call for also valuing individuality and independence. Mothers from these five nations were administered the CCC interview in which they were asked to think of both a first grade child who was doing well and then a child of the same age but the other gender. They were further asked what it was about each child that led them to think the child was doing well and how the children behaved when they were not doing well. A system was developed for coding mothers’ descriptions that classified whether descriptors represented any of five domains of development: physical, cognitive, social, emotional, and self development. In addition, when possible, mothers’ descriptors of children were further classified into subdomains in each category. The frequencies for each domain and subdomain were analyzed as a function of cultural group to identify similarities and differences in maternal conceptions of child competence.
Modelling house price developments in the Netherlands van der Windt

Disclaimer This document contains a student thesis (bachelor's or master's), as authored by a student at Eindhoven University of Technology. Student theses are made available in the TU/e repository upon obtaining the required degree. The grade received is not published on the document as presented in the repository. The required complexity or quality of research of student theses may vary by program, and the required minimum study period may vary in duration.
Docetaxel and fluid retention: Use of single-dose dexamethasone

19635 Background: Docetaxel (T) is generally well tolerated but fluid retention has been reported following therapy. This can be prevented with dexamethasone (D) but dexamethasone has its own side effects. Methods: Retrospective IRB-approved review of adult patients (pts) treated with T between March 2003 and February 2006 receiving single dose D prior to T. End point was development of fluid retention: edema, weight gain and/or pleural effusion (measured by Common Toxicity Criteria). Pts with congestive hearth failure, renal failure, chronic edema or on diuretics were excluded. Prostate cancer was excluded because chemotherapy included daily prednisone Results: 94 charts were reviewed; 64 pts included. Total T dose ranged from 80 to 1,350 mg/m2 and pretreatment D dose from 8 to 20 mg. See table 1 for demographics and reason for patient exclusion. Edema developed in 7 pts (10.9 %); arms and legs were affected equally. Only 2 pts with edema had weight gain (less than grade III). Including these 2 pts weigh.
Muslim customer perceived value on customer satisfaction and loyalty: Religiosity as a moderation

This study aims to determine the effect of Muslim customer perceived value on customer satisfaction and customer loyalty of sharia banking and religiosity role in moderating the existing effect. The study population includes all customers of Sharia banking. Total samples of 104 respondents are selected by accidental sampling technique. To know and to test the research hypothesis, data are analyzed by partial least square (PLS). This study has four results. First, the Muslim customer perceived value (MCPV) variable directly affects customer satisfaction. It consists of price, emotional values, and social values variables. While the quality, Islamic physical attributes, and Islamic non-physical attributes variables directly do not affect satisfaction of Islamic banking customers. Second, Muslim customer perceived value (MCPV) variable directly affects customer loyalty. It consists of price, emotional value, physical and non-physical attributes of Islam. Moreover, quality and social value variables directly do not affect loyalty of sharia banking customers. Third, satisfaction only mediates the effect of price, emotional value, and social value variables on the loyalty of sharia banking customers. Satisfaction does not mediate the effect of quality, Islamic physical attributes, and Islamic nonphysical attributes affect the loyalty of sharia banking customers. Forth, Religiosity does not moderate the effect of Muslim customer perceived value (MCPV) variable, namely Islamic physical attributes and Islamic nonphysical attributes, on satisfaction of sharia banking customers.
Human Resources Management Practices and its Impact on Employee Commitment Mong Staffs of Road Transport Department, Perak, Malaysia

This paper intends to examine the impact of Human Resources Management (HRM) Practices on the employee commitment at Road Transport Department (RTD), State of Perak, Malaysia. There were about 500 employees in this department and a total of 220 questionnaires were distributed randomly through head of departments. The findings of the research revealed that there were positive relationships between HRM Practices and employee commitment. However, among four HRM practices dimensions (remunerations, recognitions, working environment, and training and development) that had been investigated, only working environment and training and development had significant relationship with employee commitment.