Miracle-dz/UniFAR-FTUs huggingface dataset:
A Deep Learning Framework for Beam Selection and Power Control in Massive MIMO - Millimeter-Wave Communications

A fine power control policy and beam alignment is required between the base station (BS) and user equipment (UE) to achieve the promising performance of massive multiple input multiple output (MIMO) in millimeter wave (mmWave) communications. However, obtaining the channel state information (CSI) of mmWave - massive MIMO systems is challenging. In this paper, the beam-steering technique is used to estimate the signal strength from the BS to the user. We propose a novel learning framework to determine the suitable beam for a specific user and the transmit power for minimizing the cost including the transmit power and the unsatisfied rate when the channel is unknown. In addition, we address the missing data problem, and then employ the long-short term memory (LSTM) on the temporal processed inputs to select the suitable beam. Furthermore, we design a learning agent to predict the proper transmit power from the transmitted SSBs taking into account the required transmission rate. We then validate the proposed learning framework on the Deep MIMO dataset constructed based on accurate ray-tracing channels. Numerical results show our proposed framework outperforms the state-of-the-art prediction strategies, and approximates the best performance which is obtained when the CSI is available.
Paguyuban Sumarah and Interrituality: An Enquiry to The Practice of Interreligious Ritual Participation in Sujud Sumarah

Paguyuban Sumarah is one well-known aliran kepercayaan in Indonesia existed since the 1930s. The group practised Sujud Sumarah as the most essential ritual attended by the whole member of organizations from multiple religious backgrounds and identities, gathering them in a venue of interreligious ritual participation. This paper will discuss the aspect of interrituality in Sujud Sumarah, considering it is practised by multi-religious believers through the discourse-analysis method following the framework of interrituality offered by Moyaert, an interreligious scholar from Vrije Universiteit Amsterdam. This research concludes that it is acceptable to define the implementation of Sujud Sumarah as an interreligious ritual participation, yet it could not explicitly be categorized as ‘inner-facing’ or ‘outer-facing’ interrituality as it was classified by Moyaert. This paper also demonstrated, in general, the fundamental system of belief of Sumarah was derived from syncretism and transcendent unity of religions, leading the discussion to be possibly elaborated further in the study of interreligious relations.
Evaluation of Phenolic Compounds and Pigments Content in Yellow Bell Pepper Wastes

Bell peppers are one of the most important species consumed and cultivated in Spain. Peppers are a source of carotenoids and phenolic compounds widely associated with biological activities such as antimicrobial, antiseptic, anticancer, counterirritant, cardioprotective, appetite stimulator, antioxidant, and immunomodulator. However, undersized and damaged fruits are usually wasted. Thus, in order to evaluate the phenolic content, a Box–Behnken design has been carried out to optimize the extraction from Capsicum annuum yellow pepper by ultrasound-assisted extraction (UAE). The independent factors were time (min), ethanol/water (% v/v) and solvent/sample ratio (v/w). The model was validated by ANOVA and confirmed. Furthermore, the whole pepper and the pepper without peduncles and seeds were extracted using optimal conditions and characterized by HPLC-ESI-TOF-MS. Moreover, their antioxidant activities, measured by three different methods (DPPH, ABTS, and FRAP), carotenoid composition, assessed by HPLC-MS, and chlorophyll content, assessed by a spectrophotometric method, were compared. A total of 38 polar compounds were found of which seven have been identified in pepper fruit extracts for the first time. According to the results, whole pepper (WP) samples presented higher content in phenolic acids; meanwhile, the edible portion (EP) was higher in flavonoids. No differences were found in the antioxidant activity except for the FRAP assay where the WP sample showed higher radical scavenging activity. EP samples showed the highest content of carotenoids and WP ones in chlorophylls.
Association of Antibiotic Resistance Traits in Uropathogenic Escherichia coli (UPEC) Isolates

Background Antimicrobial resistance (AMR) is a global health problem which is constantly evolving and varies spatially and temporally. Resistance to a particular antibiotic may serve as a selection and coselection marker for the same or different antibiotic classes. Therefore, this cross-sectional study was conducted to predict the association of phenotypic and genotypic resistance traits in uropathogenic Escherichia coli (UPEC). Method A total of 42 UPEC from 83 urine samples were investigated for the prevalence and association of phenotypic and genotypic AMR traits. Antibiogram profiling was carried out by Kirby–Bauer's disc diffusion method and AMR genes (ARGs) were detected by PCR. Result UPECs were isolated from 50.60% (42/83) of the samples examined. Of these, 80.95% of cases were derived from females, and 38.10% of cases were found in the age group of 21–30 years. The isolates were shown to have a high frequency of resistance to tetracycline (92.86%), followed by sulfonamide (71.43%), ampicillin (52.38%), trimethoprim-sulfamethoxazole (47.62%), and 28.57% each to streptomycin, chloramphenicol, and erythromycin. The most prevalent antimicrobial resistance genes (ARGs) in these isolates were tet(A) (78.57%), tet(B) (76.19%), sul1 (61.91%), dfrA1 (35.71%), blaSHV (26.19%), cmlA (19.05%), and CITM, qnrA, and catA1 each at 11.91%. According to statistical analysis, ampicillin, sulfonamide, trimethoprim-sulfamethoxazole, and ciprofloxacin resistance were strongly correlated with the presence of blaSHV, sul1, dfrA1, and qnrA, respectively. Nonsignificant associations were observed between ciprofloxacin-tetracycline, sulfonamide-erythromycin pairs as well as between tet(A) and tet(B) genes. Besides, coselection was also assumed in the case of chloramphenicol resistance genes, namely, catA1 and cmlA. Conclusion Both the phenotypic and genetic resistance traits were found in the UPEC isolates. Statistical association and coselection phenomena among AMR phenotypes and genotypes were also observed but required to be validated in a broad-scale study. However, these findings might have important implications for the development of an AMR prediction model to tackle future AMR outbreaks.
Efficacy of three heat-stable microbial phytases on growth performance and bone development and strength of broilers fed diets deficient in available phosphorus

Abstract A total of 2340 as-hatched Cobb500 chicks were allocated to 9 treatments, each with 13 replicate pens to evaluate the effects of either three phytase enzymes in a P-deficient diet. Starter and finisher diets consisted of a positive control (PC) and negative control 1 and 2 (NC1 and NC2, respectively). The PC, NC1, and NC2 diets had Ca:avP (available phosphorus) ratios of 0.50, 0.33, and 0.43 in the starter feed, and 0.46, 0.22, and 0.35 in the finisher feed, respectively; NC1 diets were then supplemented with Phytaverse, Quantum Blue, and Axtra-PHY at 500 and 1000 FTU/kg. Enzyme type had significant effects on body weight gain, feed conversion ratio, and production efficiency factor during the 0–7-day period. Interactions between enzyme type and inclusion levels had a significant effect on feed intake (FI) at 1–21-day (P = 0.02) and 1–35-day (P = 0.031) age. While FI decreased as Axtra-PHY inclusion levels increased from 500 to 1000 FTU/kg feed, FI increased in birds supplemented with Quantum Blue, but with no effects on Phytaverse-supplemented birds. Increasing the enzyme dose to 1000 FTU/kg feed improved bone-breaking strength but did not affect growth performance, tibia ash, Ca, or P concentration of the birds. Résumé Un total de 2340 poussins Cobb500 éclos ont été alloués à neuf traitements, chacun avec 13 enclos répliqués pour évaluer la réponse des poulets à griller à trois enzymes phytases dans une diète déficiente en P. Les diètes de démarrage et de finition consistaient d’un témoin positif (PC — « positive control »), et témoins négatifs 1 et 2 (NC — « negative control »; NC1, NC2). Les diètes PC, NC1 et NC2 avaient des rapports Ca:P disponible (Ca:avP — « calcium:available P ») de 0,50, 0,33 et 0,43 dans la diète de démarrage; et 0,46, 0,22, 0,35 dans la diète de finition; les diètes NC1 étaient alors supplémentées de Phytaverse, Quantum Blue et Axtra-PHY à raison de 500 et 1000 FTU/kg. Le type d’enzyme a eu un effet significatif sur le gain de poids corporel, le taux de conversion alimentaire (FCR — « feed conversion ratio ») et le facteur d’efficacité de production (PEF — « production efficiency factor ») durant la période de 0 à 7 jours. Les interactions entre le type d’enzyme et les niveaux d’inclusion avaient des effets significatifs sur la consommation (FI — « feed intake ») aux jours 1 à 21 (P = 0,02) et jours 1 à 35 (P = 0,031) d’âge. Tandis que le FI diminuait avec l’augmentation des niveaux d’inclusion d’Axtra-PHY de 500 à 1000 FTU/kg d’aliments, le FI a augmenté chez les poulets ayant reçu des suppléments de Quantum Blue, et il n’y a pas eu d’effet chez les poulets ayant reçu les suppléments de Phytaverse. Augmenter la dose d’enzyme à 1000 FTU/kg d’aliments a amélioré la résistance aux fractures, mais n’a pas eu d’effet sur la performance de croissance, ni les cendres du tibia, ni les concentrations de Ca ou P des poulets. [Traduit par la Rédaction]
Ocurrence enzootic hematuria in buffaloes in Brazil: epidemiological, clinical, and pathological aspects

ABSTRACT: It is reported the occurrence of enzootic hematuria (EH) in buffaloes in Brazil after performing an epidemiological survey and clinicopathological analises. To date, EH caused by ingestion of Pteridium esculentum subsp. arachnoideum, a radiomimetic plant popularly known as “bracken fern”, has not been described in this species in Brazil. Bovine EH is responsible for high economic losses in Brazil’s Southeast Region not only because of the deaths it causes, but also owing to its negative effect on productivity. In São José do Barreiro County, São Paulo, some farmers in areas with a high incidence of bovine EH have been replacing cattle with buffaloes, based on the premise that the latter would be more resistant to poisoning by ingestion of Pteridium spp. However, even though initial observations indicated that buffaloes are indeed less sensitive than cattle to the toxic principle of Pteridium spp. , cases of hematuria in this species have been reported. According to preliminary date, EH only occurs in buffaloes over six years of age. Macroscopic examination revealed a thickened urinary vesicle mucosa, along with multiple foci of ulcerated, exophytic, verrucous, and pedunculated lesions. In one of the buffaloes studied, the bladder wall was ruptured and exhibited marked secondary inflammation. Histologically, neoplastic and non-neoplastic changes similar to those described in cattle poisoned by Pteridium spp. were observed. The neoplasms found included papilloma, carcinoma in situ, urothelial carcinoma (low and high grade), inverted, microcystic, and trabecular variants, urothelial carcinoma with divergent differentiation (squamous and glandular), squamous cell carcinoma, lymphangioma, hemangioma, and hemangiosarcoma. There was also coexistence of epithelial and mesenchymal neoplasms. Bovine papillomavirus particles were not detected by polymerase chain reaction in the bladder samples analyzed.
Quercetin exerts anti-inflammatory effects via inhibiting tumor necrosis factor-α-induced matrix metalloproteinase-9 expression in normal human gastric epithelial cells

BACKGROUND Gastric injury is the most common digestive system disease worldwide and involves inflammation, which can lead to gastric ulcer or gastric cancer (GC). Matrix metallopeptidase-9 [MMP-9 (gelatinase-B)] plays an important role in inflammation and GC progression. Quercetin and quercetin-rich diets represent potential food supplements and a source of medications for treating gastric injury given their anti-inflammatory activities. However, the effects and mechanisms of action of quercetin on human chronic gastritis and whether quercetin can relieve symptoms remain unclear. AIM To assess whether tumor necrosis factor-α (TNF-α)-induced MMP-9 expression mediates the anti-inflammatory effects of quercetin in normal human gastric mucosal epithelial cells. METHODS The normal human gastric mucosa epithelial cell line GES-1 was used to establish a normal human gastric epithelial cell model of TNF-α-induced MMP-9 protein overexpression to evaluate the anti-inflammatory effects of quercetin. The cell counting Kit-8 assay was used to evaluate the effects of varying quercetin doses on cell viability in the normal GES-1 cell line. Cell migration was measured using Transwell assay. The expression of proto-oncogene tyrosine-protein kinase Src (c-Src), phospho (p)-c-Src, extracellular-signal-regulated kinase 2 (ERK2), p-ERK1/2, c-Fos, p-c-Fos, nuclear factor kappa B (NF-κB/p65), and p-p65 and the effects of their inhibitors were examined using Western blot analysis and measurement of luciferase activity. p65 expression was detected by immunofluorescence. MMP-9 mRNA and protein levels were measured by quantitative reverse transcription polymerase chain reaction (qRT–PCR) and gelatin zymography, respectively. RESULTS qRT-PCR and gelatin zymography showed that TNF-α induced MMP-9 mRNA and protein expression in a dose- and time-dependent manner. These effects were reduced by the pretreatment of GES-1 cells with quercetin or a TNF-α antagonist (TNFR inhibitor) in a dose- and time-dependent manner. Quercetin and TNF-α antagonists decreased the TNF-α-induced phosphorylation of c-Src, ERK1/2, c-Fos, and p65 in a dose- and time-dependent manner. Quercetin, TNF-α antagonist, PP1, U0126, and tanshinone IIA (TSIIA) reduced TNF-α-induced c-Fos phosphorylation and AP-1–Luciferase (Luc) activity in a dose- and time-dependent manner. Pretreatment with quercetin, TNF-α antagonist, PP1, U0126, or Bay 11-7082 reduced TNF-α-induced p65 phosphorylation and translocation and p65–Luc activity in a dose- and time-dependent manner. TNF-α significantly increased GES-1 cell migration, and these results were reduced by pretreatment with quercetin or a TNF-α antagonist. CONCLUSION Quercetin significantly downregulates TNF-α-induced MMP-9 expression in GES-1 cells via the TNFR-c-Src–ERK1/2 and c-Fos or NF-κB pathways.
Who, What, and How: Identifying Judicial Constructions of Journalism

ABSTRACT The networked era has made it increasingly difficult to define journalism and to separate it from other types of information. This is no small thing. The definition of journalism influences its practice and its role in democratic society. This article identifies themes from judicial definitions of journalism from recent U.S. state and federal cases. Jurists’ rationales for why a person is or is not a journalist have come as they face a variety of cases in which bloggers, message-board posters, website publishers, and others have claimed protections that have historically been primarily associated with traditional journalists. Ultimately, judges have constructed a discourse about journalism that combined concerns regarding how closely the process and practices the publishers used to gather and communicate the information aligned with traditional journalistic work, the public-service value of the information, and the journalistic credentials of the publisher. Though concern for how the work was created and who communicated it was crucial, jurists consistently conveyed the public-service role was most instrumental in their evaluations, often rationalizing broad expansions of what legally constitutes journalism.
Metabolic Response in Endothelial Cells to Catecholamine Stimulation Associated with Increased Vascular Permeability

Disruption to endothelial cell homeostasis results in an extensive variety of human pathologies that are particularly relevant to major trauma. Circulating catecholamines, such as adrenaline and noradrenaline, activate endothelial adrenergic receptors triggering a potent response in endothelial function. The regulation of the endothelial cell metabolism is distinct and profoundly important to endothelium homeostasis. However, a precise catalogue of the metabolic alterations caused by sustained high catecholamine levels that results in endothelial dysfunction is still underexplored. Here, we uncover a set of up to 46 metabolites that exhibit a dose–response relationship to adrenaline-noradrenaline equimolar treatment. The identified metabolites align with the glutathione-ascorbate cycle and the nitric oxide biosynthesis pathway. Certain key metabolites, such as arginine and reduced glutathione, displayed a differential response to treatment in early (4 h) compared to late (24 h) stages of sustained stimulation, indicative of homeostatic metabolic feedback loops. Furthermore, we quantified an increase in the glucose consumption and aerobic respiration in endothelial cells upon catecholamine stimulation. Our results indicate that oxidative stress and nitric oxide metabolic pathways are downstream consequences of endothelial cell stimulation with sustained high levels of catecholamines. A precise understanding of the metabolic response in endothelial cells to pathological levels of catecholamines will facilitate the identification of more efficient clinical interventions in trauma patients.
Low Adherence to the Mediterranean Diet Is Associated with Poor Socioeconomic Status and Younger Age: A Cross-Sectional Analysis of the EpiDoC Cohort

The Mediterranean diet (MD) is recognized as one of the healthiest dietary patterns as it has been consistently associated with several beneficial health outcomes. Adherence to the MD pattern has been decreasing in southern European countries for the last decades, especially among low socioeconomic groups. The aim of this study was to assess the adherence to the MD in Portugal, to evaluate regional differences, and explore associated factors (sociodemographic, economic, and lifestyles behaviors). This study used the third data collection wave of the Epidemiology of Chronic Diseases Cohort Study (EpiDoC 3). MD adherence was assessed using the Portuguese-validated MD adherence score (MEDAS) questionnaire. Non-adjusted and adjusted logistic regression models were used to assess the risk factors for low MD adherence and individual MEDAS items. In this cross-sectional evaluation of the EpiDoC 3 cohort study (n = 5647), 28.8% of the Portuguese population had low adherence to a MD. Azores and Madeira had lower adherence to the MD than the rest of the country. Younger individuals in lower income categories (e.g., ORfinding it very difficult = 1.48; 95% CI 1.16–1.91) and with a lower educational level (e.g., OR0–4 years = 2.63; 95% CI 2.09–3.32) had higher odds of having a lower adherence to the MD. Portuguese adults have a high prevalence of low adherence to the MD, especially among those who are younger and have lower socioeconomic status. Public health policies to promote adherence to the MD should pay special attention to these groups.
Bioremediation of Perfluoroalkyl Substances (PFAS) by Anaerobic Digestion: Effect of PFAS on Different Trophic Groups and Methane Production Accelerated by Carbon Materials

Per- and polyfluoroalkyl substances (PFAS) are recalcitrant pollutants which tend to persist in soils and aquatic environments and their remediation is among the most challenging with respect to organic pollutants. Anaerobic digestion (AD) supplemented with low amounts of carbon materials (CM), acting as electron drivers, has proved to be an efficient process for the removal of organic compounds from wastewater. This work explores the impact of PFAS on different trophic groups in anaerobic communities, and the effect of carbon nanotubes (CNT), activated carbon (AC), and oxidized AC (AC-HNO3), as electron shuttles on the anaerobic bioremoval of these compounds, based on CH4 production. The inhibition of the specific methanogenic activity (SMA) exerted by perfluorooctanoic acid (PFOA) and perfluorooctane sulfonate (PFOS), at a concentration of 0.1 mg L−1, was below 10% for acetoclastic and below 15%, for acetogenic communities. Hydrogenotrophic methanogens were not affected by the presence of PFAS. All CM reduced the negative impact of PFAS on the CH4 production rate, but AC was the best. Moreover, the methanization percentage (MP) of sewage sludge (SS) increased 41% in the presence of PFOS (1.2 g L−1) and AC. In addition, AC fostered an increase of 11% in the MP of SS+PFOS, relative to the condition without AC. AC promoted detoxification of PFOA- and PFOS-treated samples by 51% and 35%, respectively, as assessed by Vibrio fischeri assays, demonstrating the advantage of bringing AD and CM together for PFAS remediation.
Perinatal Mortality and its Causes in a Rural Block in Tamil Nadu, Southern India: A Community-Based Nonconcurrent Cohort Study

Background: Globally, over 130 million babies are born every year, and almost 8 million die before their first birthday. Data on perinatal mortality (PM) and its various causes are lacking in many parts of the world including India. Objectives: This study aimed to estimate stillbirth (SB), early neonatal, and PM rates and its causes over the last decade in a rural development block, India. Materials and Methods: This is a nonconcurrent cohort study, analyzing the births, SBs, and early neonatal deaths between January 2008 and December 2017. The World Health Organization-PM classification was used to allocate causes of death as well as maternal risk factors. Birth weights were classified using standard growth charts. Results: There were 20,704 births after 28 weeks gestation and where the fetus weighed more than 1000 g of which 285 were SBs. There were 20,419 live births with 229 early neonatal deaths. There was a significant decline in PM rate from 32 per 1000 to 11 per 1000. There was a decrease in the small for gestational age fetuses from 20% to 12.5%. The main cause for SBs was antepartum hypoxia (34.4%) and fetal growth disorders (26.3%). Complications of intrapartum events contributed to 32.8% of the early neonatal deaths. Conclusion: Steady decline in PM rate and in the number of small for gestational age fetuses over 10 years was seen. Pregnancy registration and follow-up help in giving us a better understanding of the causes of PM.
The effect of introducing a Loan-to-Value limit on home ownership

We analyze the impact of the introduction of a Loan-to-Value (LTV) limit in The Netherlands on the probability for first time buyers to become home-owner using a duration model. Our research design is underpinned by a theoretical model that shows that a lower LTV limit results in suspending or never entering homeownership, but only for liquidity-constrained individuals. We use this finding to construct a treatment and control group with parents’ financial wealth as a proxy for being liquidity constrained. We disentangle the effects of the LTV limit on the timing of the transition to first time home-ownership from other market developments and show that the effect of the LTV limit on this transition is small.