Miracle-dz/UniFAR-FTUs huggingface dataset:
Double Papillary Flap - A Treatment for Gingival Recession

Esthetic concerns of the patient have become an essential part of dentistry, especially Periodontics. Periodontal plastic surgery is a rapidly emerging field, which helps us to meet this criterion. Marginal tissue recession can cause the major functional and esthetic problems. It has been clinical related to higher incidence of root caries, attachment loss, root sensitivity and smile related concerns. Root coverage is being achieved by a variety of techniques namely pedicle grafts and free soft tissue grafts. This paper highlights on case series in which a double papillary flap technique has been used for root coverage.
Accountability through Sustainability Data Governance: Reconfiguring Reporting to Better Account for the Digital Acceleration

Accountability assessment is a highly relevant challenge for companies nowadays. The COVID-19 pandemic prompted a digital acceleration in business environments, which in turn brought more focus on sustainability practices that could help organizations better demonstrate their accountability, thus making them more resilient to the ever-changing socio-economic context. Therefore, this paper aims to evaluate how to further improve corporate accountability (on a strategic and operational level), taking advantage of the digitalization changes that companies are being forced to go through and applying them to the sustainability evaluation process, including the reporting as its final output. The first research outcome is a combined framework, based on data governance and sustainability literature models, seeking to optimize the manageability of sustainability data. The second outcome is a matrix, based on a content analysis of 20 sustainability reports, representing eight possible types of behavior that companies adopt when integrating digitalization practices into their sustainability evaluation process. The aim is to explore how the communication of digital activities could refine the diligence of the sustainability assessment process, with disclosure representing its last step. Finally, the ‘leading’ case was broken down into the general strategic components that could potentially be included in a balanced data-sustainability reporting strategy.
Insights into déjà vu: Associations between the frequency of experience and amplitudes of low‐frequency oscillations in resting‐state functional magnetic resonance imaging

The phenomenon of déjà vu (DV) has intrigued scientists for decades, yet its neurophysiological underpinnings remain elusive. Brain regions have been identified in which morphometry differs between healthy individuals according to the frequency of their DV experiences. This study built upon these findings by assessing if and how neural activity in these and other brain regions also differ with respect to DV experience. Resting‐state fMRI was performed on 68 healthy volunteers, 44 of whom reported DV experiences (DV group) and 24 who did not (NDV group). Using multivariate analyses, we then assessed the (fractional) amplitude of low‐frequency fluctuations (fALFF/ALFF), a metric that is believed to index brain tissue excitability, for five discrete frequency bands within sets of brain regions implicated in DV and those comprising the default mode network (DMN). Analyses revealed significantly lower values of fALFF/ALFF for specific frequency bands in the DV relative to the NDV group, particularly within mesiotemporal structures, bilateral putamina, right caudatum, bilateral superior frontal cortices, left lateral parietal cortex, dorsal and ventral medial prefrontal cortex, and the posterior cingulate cortex. The pattern of differences in fALFF/ALFF measures between the brains of individuals who have experienced DV and those who have not provides new neurophysiological insights into this phenomenon, including the potential role of the DMN. We suggest that the erroneous feeling of familiarity arises from a temporary disruption of cortico‐subcortical circuitry together with the upregulation of cortical excitability.
Safety-limit curves for earthing system designs: appraisal of standard recommendations

The tolerable voltage limits and the maximum predicted voltage values calculated using empirical formulae given in five currently applicable standards, namely IEEE 80 (2000), EA-TS 41-24 (1992), BS 7354 (1990), ITU-T K.33 (1996) and CENELEC HD 637 S1 (1999) are compared. The calculated results from CDEGS-HIFREQ are also included. The step, touch and mesh voltages, and hot zones are calculated according to the recommendations given in the five standards, and the differences between them are investigated and clarified. The results show that IEEE 80 with 50 kg body weight touch voltage case gives the lowest tolerable limits whereas BS 7354 gives the highest in most cases. The maximum predicted touch voltage obtained from CDEGS-HIFREQ is higher than that obtained from the empirical formulae of EA-TS 41-24 and BS 7354, and the mesh voltage is lower than that from IEEE 80. The derivation of 'safety limit-curves' is proposed related to the magnitude and duration of fault current for a given earthing grid design based on the assumptions used in each standard. Following this new proposed procedure, it is established that, if the fault current parameters, i.e. grid current magnitude and duration, are within the safety zone of IEEE 80, they also satisfy the criteria of EA-TS 41-24 and BS 7354.
Combining δ13C and δ15N from bone and dentine in marine mammal palaeoecological research: insights from toothed whales

Stable carbon (δ13C) and nitrogen (δ15N) isotope compositions of bone and dentine collagen extracted from museum specimens have been widely used to study the paleoecology of past populations. Due to possible systematic differences in stable isotope values between bone and dentine, dentine values need to be transformed into bone-collagen equivalent using a correction factor to allow comparisons between the two collagen sources. Here, we provide correction factors to transform dentine δ13C and δ15N values into bone-collagen equivalent for two toothed whales: narwhal and beluga. We sampled bone and tooth dentine from the skulls of 11 narwhals and 26 belugas. In narwhals, dentine was sampled from tusk and embedded tooth; in beluga, dentine was sampled from tooth. δ13C and δ15N were measured and intraindividual bone and dentine isotopic compositions were used to calculate correction factors for each species. We detected differences in δ13C and δ15N. In narwhals, we found (i) lower average δ13C and δ15N in bone compared with dentine; (ii) no difference in dentine δ13C between tusk and embedded tooth. For belugas, we also detected lower δ13C and δ15N in bone compared with tooth dentine. The correction factors provided by the study enable the combined analysis of stable isotope data from bone and dentine in these species.
Referees', coaches', and experts' opinions on the utilisation of the rules in the teaching-learning process of mini-basketball

Rules affect the technical-tactical elements since they establish the limits on the players' actions in relation to the ball and the rest of the players. However, there are very few references that discuss this topic. Thus, it was decided to get familiar with the opinions of experts, referees, and coaches regarding the utilisation of the rules and regulations at the mini-basketball stage. The sample was made up of 9 subjects who were interviewed: three coaches, three referees, and three experts. All had university degrees and certification from the federation as well as experience in the mini- basketball division. The instrument that was used was the semi-structured interview. The Delphi method was followed for the design of the interview, and 5 university professors participated in selecting the dimensions and questions. After the definitive composition and the pilot study, the various professionals from the sample were contacted and interviewed. The content of the interviews was recorded and transcribed. The coding was done by four researchers, and the reliability was assured by the Kappa index, of which the mean index was K = . 78. The analysis was done with MXQDA 10 and SPSS 20. The participants insist on the importance of teaching the rules to the players when they begin playing basketball, given that this learning allows them to understand the internal logic of the game. Further, they explain the need for this relationship in the learning process and it even opens up the possibility for programming around the rules, given that they are what give the game and its technical-tactical elements meaning.
A Virtual View of Occupation: Transactionalism in MMORPGs

To date, most research on massive multiplayer online role-playing games (MMORPGs) has focused on the effects playing MMORPGs has on players’ health and wellness. The virtual environment of MMORPGs has yet to be explored as a space where meaningful occupations occur. This qualitative study explored the virtual environment using a transactional perspective in order to define the qualities of virtual worlds, how transactional relationships operate more clearly within these virtual worlds to construct occupational meaning, and subsequently to provide a foundation of qualitative data to support future research including virtual worlds. The sample included six MMORPG players with experience playing either World of Warcraft, RuneScape, or Guild Wars 2. Based on player interviews and participant observation, four themes related to the construction of meaning within online gaming emerged from the data: the gaming environment, the collective occupational experience, the individual occupational experience, and game transactions. Players described how customizable individual experiences as well as the communal nature of gaming motivated their engagement in MMORPGs. The virtual environment was described as providing immersion in place through interaction with other players, environmental items, and engagement in in-game occupations. The following five transactional agents were identified as contributing to the construction of meaning within MMORPGS: the player, the player community, third-party content creators, game industry manufacturers, and developers. These findings provide occupational scientists with an increased understanding of the qualities of virtual environments and how meaning is constructed within virtual occupations for MMORPG players.
A coupled chemo‐viscoplastic cap model for simulating the behavior of hydrating cemented tailings backfill under blast loading

Although the use of blasting has become a routine in contemporary mine operations, there is a lack of knowledge on the response of cement tailings backfills subjected to sudden dynamic loading. To rationally describe such a phenomenon, a new coupled chemo‐viscoplastic cap model is proposed in the present study to describe the behavior of hydrating cemented tailings backfill under blast loading. A modified Perzyna type of visco‐plasticity model is adopted to represent the rate‐dependent behavior of the cemented tailings backfill under blast loading. A modified smooth surface cap model is consequently developed to characterize the yield of the material, which also facilitates hysteresis and full compaction as well as dilation control. Then, the viscoplastic formulation is further augmented with a variable bulk modulus derived from a Mie–Gruneisen equation of state, in order to capture the nonlinear hydrostatic response of cemented backfills subjected to high pressure. Subsequently, the material properties required in the viscoplastic cap model are coupled with a chemical model, which captures and quantifies the degree of cement hydration. Thus, the behavior of hydrating cemented backfills under the impact of blast loading can be evaluated under any curing time of interest. The validation results of the developed model show a good agreement between the experimental and the predicted results. The authors believe that the proposed model will contribute to a better understanding of the performance of cemented backfills under mine blasting and contribute to evaluating and managing the risk of failure of backfill structures under such a dynamic condition. Copyright © 2015 John Wiley & Sons, Ltd.
Asymmetric Lateralization during Pain Processing

Pain is defined as “an unpleasant sensory and emotional experience associated with, or resembling that associated with, actual or potential tissue damage”. This complex perception arises from the coordinated activity of several brain areas processing either sensory–discriminative or affective–motivational components. Functional studies performed in healthy volunteers revealed that affective–emotional components of pain are processed bilaterally but present a clear lateralization towards the right hemisphere, regardless of the site of stimulation. Studies at the cellular level performed in experimental animal models of pain have shown that neuronal activity in the right amygdala is clearly pronociceptive, whilst activation of neurons in the left amygdala might even exert antinociceptive effects. A shift in lateralization becomes evident during the development of chronic pain; thus, in patients with neuropathic pain symptoms, there is increased activity in ipsilateral brain areas related with pain. These observations extend the asymmetrical left–right lateralization within the nervous system and provide a new hypothesis for the pathophysiology of chronic forms of pain. In this article, we will review experimental data from preclinical and human studies on functional lateralization in the brain during pain processing, which will help to explain the affective disorders associated with persistent, chronic pain.
Metazoan Parasites Infecting Xiphias gladius from the Eastern Coast of Algeria (SW Mediterranean Sea)

Five specimens of Xiphias gladius Linnaeus, 1758 were sampled from the eastern coast of Algeria and examined for their metazoan parasites. Pathological effects of the collected parasites were examined for the whole body of X. gladius. Four metazoan parasites species were collected: two monogeneans (Tristoma coccineum Cuvier, 1817; T. integrum Diesing, 1850), one copepod (Pennella instructa (Wilson, 1917)) and one parasitic nematode (Hysterothylacium aduncum (Rudolphi, 1802)). We report here for the first time a symbiotic species, Conchoderma virgatum Spengler, 1789 (Cirripedia) fixed on P. instructa. Collected monogenean and the copepod species are newly recorded for Algerian coast. Xiphias gladius is a new host for H. aduncum in the studied region. All examined specimens were infected (P = 100 %). The collected copepod parasite, P. instructa (P = 60 %) induces serious pathological effects to its host (necrosis and hemorrhage particularly). Histological sections showed that this copepod causes skin lesions, deteriorations on the dermal and muscle tissue.
Towards Understanding Excited-State Properties of Organic Molecules Using Time-Resolved Soft X-ray Absorption Spectroscopy

The extension of the pump-probe approach known from UV/VIS spectroscopy to very short wavelengths together with advanced simulation techniques allows a detailed analysis of excited-state dynamics in organic molecules or biomolecular structures on a nanosecond to femtosecond time level. Optical pump soft X-ray probe spectroscopy is a relatively new approach to detect and characterize optically dark states in organic molecules, exciton dynamics or transient ligand-to-metal charge transfer states. In this paper, we describe two experimental setups for transient soft X-ray absorption spectroscopy based on an LPP emitting picosecond and sub-nanosecond soft X-ray pulses in the photon energy range between 50 and 1500 eV. We apply these setups for near-edge X-ray absorption fine structure (NEXAFS) investigations of thin films of a metal-free porphyrin, an aggregate forming carbocyanine and a nickel oxide molecule. NEXAFS investigations have been carried out at the carbon, nitrogen and oxygen K-edge as well as on the Ni L-edge. From time-resolved NEXAFS carbon, K-edge measurements of the metal-free porphyrin first insights into a long-lived trap state are gained. Our findings are discussed and compared with density functional theory calculations.
Effect of herbicides and their combination on weed dynamics in rice-based cropping system

A field experiment was conducted at Zonal Agricultural Research Station, Mandya, Karnataka to study the shift in weed flora of different weed species due to application of pre-sowing, pre-emergence and post-emergence application of herbicides in comparisons with hand weeding and mechanical weeding. The effect of combination of herbicide bensulfuron-methyl + pretilachlor as well as mono-herbicide butachlor and their post-planting application were evaluated for their bio-efficacy either alone or combination with pre-planting application of non-selective glyphosate application. The treatment comprised of eight different weed management practices were laid out in randomised complete block design with three replications. The results revealed that application of glyphosate (15 days before transplanting of rice 0.75 kg/ha) in combination with bensulfuron methyl + pretilachlor applied at 5 DAT recorded higher grain yield of 7.02 t/ha and found significantly superior over other treatments due to reduced weed population and biomass of weeds (10.30 g/m2) and higher weed control efficiency (64.97%) when compared with weedy check. There was more than 36% reduction in the grain yield of rice due to competition with weeds in weedy plots. The rice yield and weed control efficiency of herbicide combination was at par with recommended practice of hand weeding twice at 20 and 40 DAT. Sequential herbicide application is promising and effective in control of weeds as compared to single herbicide application in rice-based cropping system.
EXAMINING ENTREPRENEURIAL ORIENTATION – PERFORMANCE RELATIONSHIP AMONG CROATIAN SERVICE SMES

The relationship between entrepreneurial orientation and business performance has been widely researched. However, in scientific literature there is still a need for further clarification when observing the before mentioned concepts, especially within the service SME context. Likewise, when observing this relationship it is necessary to look into the impact of entrepreneurial orientation on individual segments of business performance, i.e. on financial and non-financial constructs. Therefore, the aim of this paper is to explore the association of entrepreneurial orientation and small and medium business performance, while observing performance both as unidimensional and multidimensional concept. Furthermore, the paper tests whether moderation effect of external environment exists between entrepreneurial orientation and business performance among Croatian service SMEs.
The Role of Patient- and Treatment-Related Factors and Early Functional Imaging in Late Radiation-Induced Xerostomia in Oropharyngeal Cancer Patients

Simple Summary In the present prospective study, we assessed the role of various Magnetic Resonance Imaging biomarkers combined with self-assessed xerostomia questionnaires and patient- and treatment-related factors, in predicting xerostomia at 12 months after chemoradiotherapy for oropharyngeal squamous cell carcinoma. We hypothesized that the integration of pre-treatment imaging biomarkers, which addresses the tissue heterogeneity and individual variations among patients, could improve the accuracy of conventional prediction models that are based only on dose information, ultimately providing a better understanding of the pathophysiological mechanisms underlying radiation induced salivary dysfunction. The implementation of multifactorial models, driven by machine learning algorithms, may improve prediction accuracy of radiation-induced toxicity and tailor individual treatment options for patients. Abstract The advent of quantitative imaging in personalized radiotherapy (RT) has offered the opportunity for a better understanding of individual variations in intrinsic radiosensitivity. We aimed to assess the role of magnetic resonance imaging (MRI) biomarkers, patient-related factors, and treatment-related factors in predicting xerostomia 12 months after RT (XER12) in patients affected by oropharyngeal squamous cell carcinoma (OSCC). Patients with locally advanced OSCC underwent diffusion-weighted imaging (DWI) and dynamic-contrast enhanced MRI at baseline; DWI was repeated at the 10th fraction of RT. The Radiation Therapy Oncology Group (RTOG) toxicity scale was used to evaluate salivary gland toxicity. Xerostomia-related questionnaires (XQs) were administered weekly during and after RT. RTOG toxicity ≥ grade 2 at XER12 was considered as endpoint to build prediction models. A Decision Tree classification learner was applied to build the prediction models following a five-fold cross-validation. Of the 89 patients enrolled, 63 were eligible for analysis. Thirty-six (57.1%) and 21 (33.3%) patients developed grade 1 and grade 2 XER12, respectively. Including only baseline variables, the model based on DCE-MRI and V65 (%) (volume of both glands receiving doses ≥ 65 Gy) had a fair accuracy (77%, 95% CI: 66.5–85.4%). The model based on V65 (%) and XQ-Intmid (integral of acute XQ scores from the start to the middle of RT) reached the best accuracy (81%, 95% CI: 71–88.7%). In conclusion, non-invasive biomarkers from DCE-MRI, in combination with dosimetric variables and self-assessed acute XQ scores during treatment may help predict grade 2 XER12 with a fair to good accuracy.
Wage Theft and Work Safety: Immigrant Day Labor Jobs and the Potential for Worker Rights Training at Worker Centers

Immigrant day laborers routinely experience exploitative behaviors as part of their employment. These experiences are understood in the context of their immigration histories and in the context of their long-term goals for less precarious labor and living situations. Using mixed methods, over three data collection periods in 2016, 2019, and 2020, we analyze the work experiences of immigrant day labors in Houston and Austin, Texas. We report how workers judge precarious jobs and respond to labor exploitation in an informal labor market. We also discuss data pertaining to a worker rights training intervention conducted through a city-sponsored worker center. We discuss the potential for worker centers to be a convening and remediation space for workers and employers. Worker centers where immigrant day labors meet employers offer the potential for informal intervention into wage theft and work safety violations, by formalizing the context where laborers are hired.
Guiding ATR and PARP inhibitor combinations with chemogenomic screens

Combinations of inhibitors of Ataxia Telangiectasia- and Rad3-related kinase (ATRi) and poly(ADP-ribose) polymerases (PARPi) synergistically kill tumor cells through modulation of complementary DNA repair pathways, but their tolerability is limited by hematological toxicities. To address this we performed a genome-wide CRISPR/Cas9 screen to identify genetic alterations that hypersensitize cells to a combination of the ATRi RP-3500 with PARPi, including deficiency in RNase H2, RAD51 paralog mutations or the Alternative Lengthening of Telomeres telomere maintenance mechanism. We show that RP-3500 and PARPi combinations kill cells carrying these genetic alterations at doses sub-therapeutic as single agents. We also demonstrate the mechanism of combination hypersensitivity in RNase H2-deficient cells, where we observe an irreversible replication catastrophe, allowing us to design a highly efficacious and tolerable in vivo dosing schedule. Altogether, we present a comprehensive dataset to inform development of ATRi and PARPi combinations and an experimental framework applicable to other drug combination strategies.