Miracle-dz/UniFAR-FTUs huggingface dataset:
Temperature Dependent Piezoelectric and Pyroelectric Response of Nb Doped (Na0.41 K0.09 Bi0.5) TiO3 Ceramics

In the present study, temperature dependence of the piezoelectric and pyroelectric coefficients of niobium (Nb) doped ($\left.\mathrm{Na} 0.41 \mathrm{~K}_{0.09} \mathrm{Bi}_{0.5}\right) \mathrm{TiO}_3$ [NKBT] ceramics has been investigated. The piezoelectric charge coefficient $\left(d_{31}\right)$ and electromechanical coupling coefficient $\left(k_{\mathrm{p}}\right)$ increase gradually with temperature till close to the depolarization temperature and thereafter fall sharply. The highest piezoelectric coefficients were obtained for $\mathrm{x}=0.005(0.5$ at. %Nb) which are $d_{33} \sim 185 \mathrm{pC} / \mathrm{N}, d_{31} \sim 51 \mathrm{pC} / \mathrm{N}$ and $\mathrm{k}_{\mathrm{p}} \sim 0.35$ at room temperature. Like the piezoelectric response, the pyroelectric coefficient also shows an anomaly in the vicinity of Td. At room temperature the pyroelectric coefficient $\left(p_3\right)$ is in the range of 2-10 $\mathrm{nC} / \mathrm{cm}^2 \mathrm{~K}$ for all the compositions. The maximum value of p3 observed near Td is $4.6 \mu \mathrm{C} / \mathrm{cm}^2 \mathrm{~K}$. The measurements reveal the lowering of Td with increase in Nb content which can be explained on the basis of donor type behavior of niobium $\left(\mathrm{Nb}^{5+}\right)$ ion. For energy harvesting, the generated output voltage shows maximum value for a periodic temperature oscillation of $\Delta \mathrm{T} \sim 15 \mathrm{~K}$ at $\mathrm{dT} / \mathrm{dt} \sim 0.44 \mathrm{~K} / \mathrm{s}$ for sample with $\mathrm{x}=0.005$. The study suggests that by using a proper rectifier circuit a pulsating DC output with maximum voltage of $\sim 3 \mathrm{~V}$ can be obtained.
Degradation Prediction of Semiconductor Lasers Using Conditional Variational Autoencoder

Semiconductor lasers have been rapidly evolving to meet the demands of next-generation optical networks. This imposes much more stringent requirements on the laser reliability, which are dominated by degradation mechanisms (e.g., sudden degradation) limiting the semiconductor laser lifetime. Physics-based approaches are often used to characterize the degradation behavior analytically, yet explicit domain knowledge and accurate mathematical models are required. Building such models can be very challenging due to a lack of a full understanding of the complex physical processes inducing the degradation under various operating conditions. To overcome the aforementioned limitations, we propose a new data-driven approach, extracting useful insights from the operational monitored data to predict the degradation trend without requiring any specific knowledge or using any physical model. The proposed approach is based on an unsupervised technique, a conditional variational autoencoder, and validated using vertical-cavity surface-emitting laser (VCSEL) and tunable edge emitting laser reliability data. The experimental results confirm that our model (i) achieves a good degradation prediction and generalization performance by yielding an F1 score of 95.3%, (ii) outperforms several baseline ML based anomaly detection techniques, and (iii) helps to shorten the aging tests by early predicting the failed devices before the end of the test and thereby saving costs.
Role of Surface Tension in Microrobot Penetration in Membranes

cell-membrane fusion using microrobots can be a useful technique for delivering bioactive compounds to cellular systems. The role of membrane curvature and lipid ordering in the cell membrane penetration process is well known. However, once the fusion into the cell membrane is already initiated, the fluid dynamics of microrobot penetration based on tension difference of the microrobot solution and membrane curvature at the fusion pore has not been explored yet. Here, we demonstrate how surface tension difference among merging interfaces plays role in microrobot droplet penetration into a liquid bath, mimicking cell membrane fusion. The maximum penetration of a microrobot droplet into a liquid bath depends on the positive difference of surface tension between the droplet and liquid bath, longitudinal curvature of the bridge region, and the size of the droplet.
Poppers by inducing HHV-8 virion production can act as a promoter for HHV-8 transmission in MSM

Environmental factors were reported to increase the risk of human herpesvirus 8 (HHV-8) transmission. In a MSM population, we evidenced that Chemsex was associated with HHV-8-seropositivity in vivo and that poppers induced HHV-8-virion production in vitro . Our finding may explain the higher HHV-8-transmission in MSM.
Institutional Knowledge at Singapore Management University PCAOB Inspection Reports and Audit Quality

With the creation of the Public Company Accounting Oversight Board (PCAOB), audit ﬁrm oversight shifted away from self-regulation to independent regulation. The inspections program is the central feature of the PCAOB. We examine whether PCAOB inspections are able to distinguish actual audit quality (as opposed to perceived) during the period inspected to better understand this important regulatory tool. We use three measures that proxy for actual audit quality: abnormal accruals, restatements, and the propensity to issue a going concern opinion. For triennially inspected auditors, we ﬁnd that PCAOB inspections are associated with lower audit quality when the reports are seriously deﬁcient (weaker results for deﬁcient reports). More speciﬁcally, we ﬁnd clients of triennially inspected auditors that receive a deﬁcient or seriously deﬁcient report are associated with signiﬁcantly higher abnormal current accruals and clients of auditors that receive a seriously deﬁcient report are associated with a greater propensity to restate. Our evidence is subject to the caveat that PCAOB reports for trien- nially inspected auditors do not capture the going concern aspect of audit quality. For annually inspected auditors, the results are conﬂicting and suggest PCAOB inspection reports do not distinguish audit quality during the period inspected for annually inspected auditors. Published by Elsevier
Samra, Rajvinder and Griffiths, Amanda and Cox, Tom and Conroy, Simon and Gordon, Ada and Gladman, John R.F. (2015) Medical students' and doctors' attitudes towards older patients and their care in hospital

Background: despite assertions in reports from governmental and charitable bodies that negative staff attitudes towards older patients may contribute to inequitable healthcare provision for older patients when compared with younger patients (those aged under 65 years), the research literature does not describe these attitudes in any detail. Objective: this study explored and conceptualised attitudes towards older patients using in-depth interviews. Methods: twenty-five semi-structured interviews with medical students and hospital-based doctors in a UK acute teaching hospital were conducted. Participants were asked about their beliefs, emotions and behavioural tendencies towards older patients, in line with the psychological literature on the definition of attitudes (affective, cognitive and behavioural information). Data were analysed thematically. Results: attitudes towards older patients and their care could be conceptualised under the headings: (i) beliefs about older patients; (ii) older patients’ unique needs and the skills required to care for them and (iii) emotions and satisfaction with caring for older patients. Conclusions: our findings outlined common beliefs and stereotypes specific to older patients, as opposed to older people in general. Older patients had unique needs concerning their healthcare. Participants typically described negative emotions about caring for older patients, but the sources of dissatisfaction largely related to the organisational setting and system in which the care is delivered to these patients. This study marks one of the first in-depth attempts to explore attitudes towards older patients in UK hospital settings.
Glycosylation of Simian Immunodeﬁciency Virus Inﬂuences Immune-Tissue Targeting during Primary Infection, Leading to Immunodeﬁciency or Viral Control

Glycans of human immunodeﬁciency virus (HIV) and simian immunodeﬁciency virus (SIV) play pivotal roles in modulating virus-target cell interactions. We have previously reported that, whereas SIVmac239 is pathogenic, its deglycosylated essentially nonpathogenic mutant ( (cid:1) 5G) serves as a live-attenuated vaccine, although both replicate similarly during primary infection. These ﬁndings prompted us to determine whether such a polarized clinical outcome was due to differences in the immune tissues targeted by these viruses, where functionally and phenotypically different memory CD4 (cid:2) T cells reside. The results showed that (cid:1) 5G replicates in secondary lymphoid tissue (SLT) 1- to 2-log-lower levels SIVmac239, SIVmac239-infected (cid:1) 5G-infected deplete CXCR3 (cid:2) CCR5 (cid:2) transitional memory (TrM) CD4 (cid:2) T cells. An early robust (cid:1) 5G replication was localized to small intestinal tissue, especially the lamina propria (effector site) rather than isolated lymphoid follicles (inductive site) and was associated with the induction and depletion of CCR6 (cid:2) CXCR3 (cid:3) CCR5 (cid:2) effector memory CD4 (cid:2) T cells. These results suggest that differential glycosylation of Env dictates the type of tissue-resident CD4 (cid:2) T cells that are targeted, which leads to pathogenic infection of TrM-Th1 cells in SLT and nonpathogenic infection of Th17 cells in the small intestine, respectively.
SELECTION OF ANTAGONISTS FOR BIOCONTROL OF Xanthomonas

Xanthomonas euvesicatoria is a worldwide causer of pepper bacterial spot, a bacterial plant disease responsible for massive losses of fresh pepper fruits. Considering the current problems in management of bacterial plant diseases, biological control using antagonistic microbial strains with high potential for plant pathogens suppression emerges as a possible solution. The aim of this study was to select suitable antagonists for suppression of X. euvesicatoria among the bacteria, yeast and fungi from the genera Pseudomonas, Lactobacillus, Saccharomyces and Trichoderma, based on in vitro antimicrobial activity testing using the diffusion disc method. The results of this study have revealed that cultivation broth samples of the antagonists Lactobacillus MK3 and Trichoderma reseii QM 9414, as well as supernatant samples of the antagonist Pseudomonas aeruginosa I128, have showed significant potential to be applied in biological control of X. euvesicatoria. Further research would be required to formulate suitable cultivation medium and optimize bioprocess conditions for production of the proposed pepper bacterial spot biocontrol agents.
Renal Hemodynamics Effect of sodium nitrite on renal function and sodium and water excretion and brachial and central blood pressure in healthy subjects: a dose-response study

Effect of sodium nitrite on renal function and sodium and water excretion and brachial and central blood pressure in subjects: a dose-response study. Am J Physiol Renal Physiol 313: F378–F387, 10.1152/ajprenal.00400. 2016. —Sodium nitrite (NaNO 2 ) is converted to nitric oxide (NO) in vivo and has vasodilatory and natriuretic effects. Our aim was to examine the effects of NaNO 2 on hemodynamics, sodium excretion, and glomerular ﬁltration rate (GFR). In a single-blinded, placebo-controlled, crossover study, we infused placebo (0.9% NaCl) or 0.58, 1.74, or 3.48 (cid:2) mol NaNO 2 ·kg (cid:3) 1 ·h (cid:3) 1 for 2 h in 12 healthy subjects, after 4 days of a standard diet. Subjects were supine and water loaded. We measured brachial and central blood pressure (BP), plasma concentrations of renin, angiotensin II, aldosterone, arginine vasopressin (P-AVP), and plasma nitrite (P-NO 2 (cid:2) ), GFR by Cr-EDTA clearance, fractional excretion of sodium (FE Na ) free water clearance (C H2O ), and urinary excretion rate of guanosine 3 = ,5 = -cyclic monophosphate (U-cGMP). The highest dose reduced brachial systolic BP (5.6 mmHg, P (cid:4) 0.003), central systolic BP (5.6 mmHg, P (cid:4) 0.035), and C H2O (maximum change from 3.79 to 1.27 ml/min, P (cid:4) 0.031) and increased P-NO 2 (cid:2) (from 0.065 to 0.766 (cid:2) mol/l, P (cid:5) 0.001), while reducing U-cGMP (from 444 to 247 pmol/min, P (cid:4) 0.004). GFR, FE Na , P-AVP, and the components in the renin-angiotensin-aldosterone system did not change signiﬁcantly. In conclusion, intravenous NaNO 2 induced a dose-dependent reduction of brachial and central BP. The hemodynamic effect was not mediated by the renin-angiotensin-aldosterone system. NaNO 2 infusion resulted in a vasopressin-independent decrease in C H2O and urine output but no change in urinary sodium excretion or GFR. The lack of increase in cGMP accompanying the increase in NO 2 (cid:2) suggests a direct effect of nitrite or nitrate on the renal tubules and vascular bed with little or no systemic conversion to NO.
PREDICTORS OF DISEASE PROGRESSION IN IDIOPATHIC DILATED (CONGESTIVE) CARDIOMYOPATHY IN PEDIATRIC AGE

study ABSTRACT Idiopathic dilated cardiomyopathy (IDCM) is a severe illness which carries a high mortality rate in the pediatric population. In order to characterize IDCM evolution and identifyprognostic predictors in the pediatric cardiology outpatient clinic of Alexandria University Children’s Hospital, allpatients with IDCM (n=22) were evaluated clinically and by echocardiography. They were followed for one year. Patients less than 10 years represented 72.7% of the cohort (n=16). Gender distribution revealed 59.1% male (n=13) and 40.9 % female (n=9). Outcomes were divided into four groups: 13.6% of patients (n=3) cured, 27.3% of patients (n=6) compensated, 50%patients (n=11) decompensated and 9.1% ofpatients (n=2) died. In this study, we found a significant correlation of prognosis with ejection fraction, end diastolic dimension of left ventricle, and shortening fraction on presentation. Also results suggested that pulmonary congestion in chest x- ray at presentation was significantly related to unfavorable outcome. Medical treatment and good compliance were associated with a statistically better prognosis. We concluded that further multi-center studies arenecessary to verify predictors of outcome in IDCM patients. Identification of markers affecting early myocardialfunction is essential to achieving improvements in treatments and consequently outcomes in this pediatricpopulation.
The Early Asexual Development Regulator fluG Codes for a Putative Bifunctional Enzyme

FluG is a long recognized early regulator of asexual development in Aspergillus nidulans. fluG null mutants show profuse aerial growth and no conidial production. Initial studies reported sequence homology of FluG with a prokaryotic type I glutamine synthetase, but catalytic activity has not been demonstrated. In this study, we conducted an in-depth analysis of the FluG sequence, which revealed a single polypeptide containing a putative N-terminal amidohydrolase region linked to a putative C-terminal γ-glutamyl ligase region. Each region corresponded, separately and completely, to respective single function bacterial enzymes. Separate expression of these regions confirmed that the C-terminal region was essential for asexual development. The N-terminal region alone did not support conidial development, but contributed to increased conidial production under high nutrient availability. Point mutations directed at respective key catalytic residues in each region demonstrated that they were essential for biological function. Moreover, the substitution of the N- and C-terminal regions with homologs from Lactobacillus paracasei and Pseudomonas aeruginosa, respectively, maintained functionality, albeit with altered characteristics. Taken together, the results lead us to conclude that FluG is a bifunctional enzyme that participates in an as yet unidentified metabolic or signaling pathway involving a γ-glutamylated intermediate that contributes to developmental fate.
Targeting I (cid:1) B Proteins for HIV Latency Activation: the Role of Individual I (cid:1) B and NF- (cid:1) B Proteins

Latently infected cell reservoirs represent the main barrier to HIV eradication. Combination antiretroviral therapy (cART) effectively blocks viral replication but cannot purge latent provirus. One approach to HIV eradication could include cART to block new infections plus an agent to activate latent provirus. NF- (cid:1) B activation induces HIV expression, ending latency. Before activation, I (cid:1) B proteins sequester NF- (cid:1) B dimers in the cytoplasm. Three canonical I (cid:1) Bs, I (cid:1) B (cid:2) , I (cid:1) B (cid:3) , and I (cid:1) B (cid:4) , exist, but the I (cid:1) B proteins’ role in HIV activation regulation is not fully understood. We studied the effects on HIV activation of targeting I (cid:1) Bs by single and pairwise small interfering RNA (siRNA) knockdown. After determining the relative abundance of the I (cid:1) Bs, the relative abundance of NF- (cid:1) B subunits held by the I (cid:1) Bs, and the kinetics of I (cid:1) B degradation and resynthesis following knockdown, we studied HIV activation by I (cid:1) B knockdown, in comparison with those of known HIV activators, tumor necrosis factor alpha (TNF- (cid:2) ), tetradecanoyl phorbol acetate (TPA), and trichostatin A (TSA), in U1 monocytic and J-Lat 10.6 lymphocytic latently infected cells. We found that I (cid:1) B (cid:2) knockdown activated HIV in both U1 and J-Lat 10.6 cells, I (cid:1) B (cid:3) knockdown did not activate HIV, and, surprisingly, I (cid:1) B (cid:4) knockdown produced the most HIV activation, comparable to TSA activation. Our data show that HIV reactivation can be triggered by targeting two different I (cid:1) B proteins and that I (cid:1) B (cid:4) may be an effective target for HIV latency reactivation in T-cell and macrophage lineages. I (cid:1) B (cid:4) knockdown may offer attractive therapeutic advantages for HIV activation because it is not essential for mammalian growth and development and because new siRNA delivery strategies may target siRNAs to HIV latently infected cells.
Variable stars in the Cetus dwarf spheroidal galaxy

We investigate the variable star content of the isolated, Local Group, dwarf spheroidal (dSph) galaxy Cetus. Multi-epoch, wide-field images collected with the Very Large Telescope/Visible Multiobject Spectrograph camera allowed us to detect 638 variable stars (630 RR Lyrae stars and eight anomalous Cepheids), 475 of which are new detections. We present a full catalogue of periods, amplitudes and mean magnitudes. Motivated by the recent discovery that the pulsational properties of the RR Lyrae stars in the Tucana dSph revealed the presence of a metallicity gradient within the oldest (>rsim10 Gyr old) stellar populations, we investigated the possibility of an analogous effect in Cetus. We found that, despite the obvious radial gradient in the horizontal branch and red giant branch morphologies, both becoming bluer on average for increasing distance from the centre of Cetus, the properties of the RR Lyrae stars are homogeneous within the investigated area (out to r∼ 15 arcmin), with no significant evidence of a radial gradient. We discuss this in connection with the star formation history previously derived for the two galaxies. The observed differences between these two systems show that even systems this small show a variety of early evolutionary histories. These differences could be due to different merger or accretion histories.
Color bimodality: Implications for galaxy evolution

We use a sample of 69726 galaxies from the SDSS to study the variation of the bimodal color‐magnitude (CM) distribution with environment. Dividing the galaxy population by environment (Σ5) and luminosity (−23 < Mr < −17), the u − r color functions are modeled using double‐Gaussian functions. This enables a deconvolution of the CM distributions into two populations: red and blue sequences. The changes with increasing environmental density can be separated into two effects: a large increase in the fraction of galaxies in the red distribution, and a small color shift in the CM relations of each distribution. The average color shifts are 0.05 ± 0.01 and 0.11 ± 0.02 for the red and blue distributions, respectively, over a factor of 100 in projected neighbor density. The red fraction varies between about 0% and 70% for low‐luminosity galaxies and between about 50% and 90% for high‐luminosity galaxies. This difference is also shown by the variation of the luminosity functions with environment. We demonstrate tha.
Naphtha (petroleum), hydrotreated heavy

Synonyms Hydrocarbons, paraffinic and naphthenic, C6–C13, boiling points between 65 and 230 °C, aromatic-free Stoddard solvent IIC1) White spirit, dearomatized1) (white spirit Type 3) Chemical name – CAS number 64742-48-9 Formula – Molecular weight – Melting point < −50°C (Shell 2007) Boiling point at 1013 hPa 65–230°C Density at 15°C 0.781 g/cm3 (Shell 2007) Vapour pressure at 20°C – log KOW – 1 ml/m3 (ppm)≙ 6 mg/m3 1 mg/m3≙ 0.167 ml/m3 (ppm) Solubility insoluble in water
Does the Right to be Forgotten Work in Social Machines Context?

— This paper presents a reflection about the right to be forgotten in the context of social machines operating in Web 3.0 and present this "new" distribution of information environment. The reflection was based on a literature review and suggests the ineffectiveness of how the right to be forgotten is being applied due the complex structures existing connection between users, social software and devices (hardware) designed to work together. Thus, disconnecting more than a right, becomes a duty for those who choose to be forgotten.