Miracle-dz/UniFAR-FTUs huggingface dataset:
How does a CBT-based transdiagnostic program for separation anxiety symptoms work in children? Effects of Super Skills for Life

espanol? Es eficaz un programa transdiagnostico basado en TCC para los sintomas de ansiedad por separacion infantil? Resultados del programa Super Skills. Super Skills for Life (SSL) es un programa transdiagnostico de origen anglosajon basado en la terapia cognitiva conductual, dirigido a tratar problemas emocionales infantiles. Se ha traducido e implementado en poblacion espanola, logrando reducciones significativas en sintomas de ansiedad y depresion. El objetivo del presente estudio fue examinar la eficacia a corto y largo plazo de SSL en escolares con ansiedad por separacion. Participaron 86 ninos hispanohablantes de 8 a 12 anos, que fueron evaluados antes de recibir la intervencion, inmediatamente despues y 12 meses despues. Los resultados indicaron mejoras estadisticamente significativas tanto en el problema principal, la ansiedad por separacion, como en otros sintomas o problemas comorbidos (depresion, problemas de comportamiento, problemas con los companeros, interferencia de ansiedad en la vida diaria, etc.). En general, los resultados muestran que el programa fue mas efectivo a largo plazo que a corto plazo. Los hallazgos del estudio sugieren que SSL puede ser util para tratar problemas emocionales en ninos con ansiedad por separacion. Se discuten las implicaciones practicas de estos hallazgos. EnglishSuper Skills for Life (SSL) is a transdiagnostic program of Anglo-Saxon origin based on cognitive behavioural therapy, aimed at treating emotional problems in children. It has been translated and implemented in the Spanish population, achieving significant reductions in anxious and depressive symptoms. The objective of the current study was to examine the short- and long-term efficacy of SSL in schoolchildren with separation anxiety. The program was attended by 86 Spanish-speaking children aged 8-12 years, who were evaluated before receiving the intervention, immediately after and 12 months later. Results indicated statistically significant improvements both in the main problem, separation anxiety and other comorbid symptoms or problems (depression, behaviour problems, problems with peers, interference of anxiety in daily life, etc.). Overall, the results show that the program was more effective in the long-term than in the short-term. The findings of the study suggest that SSL can be useful for treating emotional problems in children with separation anxiety. Clinical implications of these findings are discussed.
Revealing Hi-C subcompartments by imputing high-resolution inter-chromosomal chromatin interactions

The higher-order genome organization and its variation in different cellular conditions remains poorly understood. Recent high-resolution genome-wide mapping of chromatin interactions using Hi-C has revealed that chromosomes in the human genome are spatially segregated into distinct subcompartments. However, due to the requirement on sequencing coverage of the Hi-C data to define subcompartments, to date subcompartment annotation is only available in the GM12878 cell line, making it impractical to compare Hi-C subcompartment patterns across multiple cell types. Here we develop a new computational approach, named Sniper, based on an autoencoder and multilayer perceptron classifier to infer subcompartments using typical Hi-C datasets with moderate coverage. We demonstrated that Sniper can accurately reveal subcompartments based on Hi-C datasets with moderate coverage and can significantly outperform an existing method that uses numerous epigenomic datasets as input features in GM12878. We applied Sniper to eight additional cell lines to identify the variation of Hi-C subcompartments across different cell types. Sniper revealed that chromosomal regions with conserved and more dynamic subcompartment annotations across cell types have different patterns of functional genomic features. This work demonstrates that Sniper is effective in identifying subcompartments without the need of high-coverage Hi-C data and has the potential to provide new insights into the spatial genome organization variation across different cell types.
Analysis of land surface temperatures in the "Local Climate Zones" of Novi Sad (Serbia)

In this study, the Local Climate Zones (LCZs) in Novi Sad, the second largest city in Serbia, are analysed as to surface temperature differences. The LCZs were delineated on the basis of the GIS-based method created by Geletic & Lehnert (2016). Land Surface Temperatures (LSTs) were derived from the satellites Terra, sensor ASTER, and LANDSAT-8. The thermal images were provided at a similar time (at about 9.30 AM) between 2002 and 2008 (ASTER) and between 2013 and 2017 (LANDSAT-8). Statistical analyses, including the analysis of variance (ANOVA) and Tukey-HSD test, were employed to reveal LST differences between the LCZs. The results indicate that in 84% of cases there were significant differences in LST between pairs of LCZs. Temperature differences between LCZs were the most pronounced in the summer season. In general, 8 (large low-rise), 10 (heavy industry), 2 (compact midrise) and 3 (compact low-rise) LCZs had the highest surface temperatures in Novi Sad. Contrary to this, LCZs A (dense trees), B (scattered trees) G (water bodies) were the coolest zones.
Microstructural properties and tribological behaviours of Ultra-High frequency induction rapid sintered Al-WC composites

espanolEn este estudio, se analiza la sinterabilidad de composites de matriz de aluminio reforzados con WC 1, 3, 5, 9 y 15% (en peso) y obtenidos por induccion rapida y metodos tradiconales. El procedimiento seguido fue, en primer lugar, presionar mediante un metodo de prensado en frio no axial con una presion de 200 MPa. Algunas de estas muestras patrones se sinterizaron mediante un metodo de sinterizacion por induccion rapida a ultra alta frecuencia, durante 300 s a temperatura de 600 °C. Otras muestras se sinterizaron a 600 °C durante 1800 s. Se midieron los valores de densidad y dureza de los composites sinterizados y se ensayaron las propiedades microestructurales, y el comportamiento de abrasion y de friccion. Se observo que si se aumentaba la relacion de refuerzo de WC la resistencia a la abrasion y el coeficiente de friccion tambien aumentaban. Finalmente, el estudio mostro que la sinterizacion a ultra alta frecuencia es una alternativa tan valida como el metodo tradicional de obtencion de composites de Al-WC. EnglishIn this study, sinterability of 1, 3, 5, 9 and 15 wt. % WC reinforced aluminum matrix composite samples by induction fast and conventional sintering methods was investigated. For this purpose, firstly, it was pressed by unaxial cold pressing method under 200 MPa pressure. Some of these raw samples were sintered by ultra-high frequency induction fast sintering method at 600 oC temperature for 300 sec. , while the other part of the samples were sintered by 600 °C for 1800 sec. The density and hardness values of sintered composite samples were measured and microstructural properties, abrasion and friction behaviours were investigated. In this study, it was seen that increased WC reinforcement ratio and abrasion resistance and friction coefficient increased together. In addition, this study showed that ultra-high frequency sintering is as successful as traditional method in Al-WC composite production.
Eight weeks of Curcuma longa L. supplementation improves disease activity and quality of life in Ulcerative Colitis patients: a pilot study

This study evaluated the effects of Curcuma longa L, combined with Mesalamine on inflammation and quality of life in patients with Ulcerative Colitis (UC). A randomized, double-blind, pilot study was undertaken with nine patients, age ≥18 years, who were exclusively using Mesalamine (3g/day). These patients were kept under observation in a university hospital for eight weeks. An experimental group (EG) (n=5) received three capsules daily, containing 500mg of dry extract of Curcuma longa L. and a control group (CG) (n=4), 500mg of microcrystalline cellulose. The groups were evaluated for the following, before and after the intervention: rectosigmoidoscopy, fecal calprotectin, body mass index (BMI), interleukin 10 (IL10), C-reactive protein (CRP), haemoglobin and haematocrit. A Short Form Health Survey (SF36) questionnaire was used to assess quality of life. When individually evaluated, EG patients showed histological improvement (Effect size: 0.706) in the rectosigmoidoscopy examination. 80% of them presented calprotectin values within the normal range. BMI analysis showed that 78% of the patients were overweight, but without difference between groups (p=0.456). The inflammation markers (IL10, CRP and calprotectin) as well as haemoglobin and haematocrit were not different in any of the groups. There was no difference in the SF-36 quality of life domains between groups, but the effect size was medium to large for the domains physical functioning, bodily pain, general health, social functioning, role-emotional and mental health. As conclusion the turmeric supplementation for eight weeks was able to reduce the Mayo score and improve the quality of life in patients with UC.
Bud load management on table grape yield and quality – cv. Sugrathirteen (Midnight Beauty®)

Bragantia, Campinas, v. 77, n. 4, p.577-589, 2018 ABSTRACT: Viticulture is an activity of great economic and social importance in the Submedium region of the São Francisco River Valley, with emphasis on table grape and wine production. With the increasing expansion of the viticulture, a growing number of alternatives that do not affect fruit quality have been studied to maximize table grape yield, such as pruning and load adjustment. The aim of the present study was to evaluate the influence of different bud loads on canopy management to enable the marketable and economic production of cv. Sugrathirteen (Midnight Beauty®) in the submedium region of the São Francisco River Valley. This study was carried out for two years (2014/2015) in an experimental area for the introduction of new cultivars patented by Prodomo Farm in the municipality of Petrolina, CROP PRODUCTION AND MANAGEMENT Article
Dietary Mannanoligosaccharide Supplementation Improves Growth Performance, Intestinal Integrity, Serum Immunity, and Antioxidant Capacity of Partridge Shank Chickens

Herein, we assessed the impact of dietary addition of konjac mannanoligosaccharide (MOS) on the growth, intestinal morphology, serum immune status, and oxidative status in Partridge Shank chickens. For the experiment, one-day-old chicks (n=192) were randomized into six replicates (n=8/replicate) and fed four different diets: a basal diet containing 0 (Control group), 0.5, 1, or 1.5 g MOS per kg of diet (g/kg) for 50 d. Relative to the control, the group fed 0.5 g/kg MOS decreased feed consumption from 22nd to 50th d and 1st to 50th d (P<0.05). By adding MOS, the height of the intestinal villus and the villus height to crypt depth ratio were increased (P<0.05); 1.5 g/kg MOS was the best dosage for these parameters. Jejunal and ileal goblet cell density increased following MOS supplementation at 21 d (P<0.01) and 50 d in the jejunum (P<0.05), respectively. Moreover, adding MOS to the diet increased the contents of IgA and IgM at 21 d (P<0.05) and total antioxidant capacity (P<0.05) at 50 d in the serum but decreased malondialdehyde content (P<0.01) at 21 d in the group fed 0.5 and 1.5 g/kg MOS. The findings suggested that MOS supplementation could affect feed consumption, intestinal health, serous immunity, and antioxidant capacity of Partridge Shank chickens.
Effect of polymer and polymer blends on encapsulation efficiency of spray-dried microencapsulated flaxseed oil.

Flaxseed oil emulsions were prepared by homogenising flaxseed oil, gum Arabic (GA), maltodextrin (MD), and inulin (IN) in water (polymers were used alone and in combinations). Emulsions were analysed for their stability and viscosity. Results indicated that emulsions containing IN showed some layer separation while most of the emulsions were stable before spray-drying. The microparticles obtained after spray-drying were analysed for encapsulation efficiency, surface oil, density, flowing properties, moisture, water activity, colour parameters (L*, a*and b*), particle size, morphology, dissolution behaviour, X-ray diffraction (XRD) pattern, and differential scanning colorimetery (DSC). All the encapsulated flaxseed oil powders (EFOPs) showed a bimodal particle size distribution with average particle size in the range of 1.18 to 9.80 μm. GA:MD (1:1) showed the highest encapsulation efficiency (92%) and lower surface oil. Scanning electron micrographs depicted spherical particles with no apparent cracks. IN yielded smooth-surfaced microparticles. DSC thermograms depicted that microcapsules were thermally stable. XRD analysis showed that most of the EFOPs were amorphous and spray-drying did not change the structure of wall materials. Dissolution behavior showed that presence of IN increased the solubility of EFOPs in water at room temperature. Hence, it is concluded that IN and MD effectively support GA in encapsulating flaxseed oil.
Assessment of Antibacterial Activity and Phytochemical Screening of Hemidesmus indicus Root Extracts

The Hemidesmus indicus is used to cure leprosy, leucoderma, itching, skin disease, asthma, bronchitis, leucorrhoea, dysentery, piles, syphilis, and paralysis. The present study was aimed to investigate the phytochemical and antibacterial activity of Hemidesmus indicus root. The root extracts of Hemidesmus indicus were prepared using different solvents like petroleum ether, ethanol and distilled water. The phytochemical screening of the root extracts was performed. The presence of alkaloids, glycosides, carbohydrates, steroids, polyphenol, saponins and terpenoids were indicated by the test conducted. The antibacterial activity of the ethanol and aqueous extract of Hemidesmus indicus root was tested by agar diffusion method. Zones of Inhibition produced by both extract in a dose of 100 and 200 mg/ml against selected strains was measured and compared with those of standard drug ciprofloxacin (10 μg/ml). Both extract recorded significant activity against all the test bacteria. The highest zones of growth inhibition were exhibited by ethanol extract against all the microorganisms compared to be aqueous extract.
The comparative seasonal biology studies of banana leaf roller, Erionota torus evans under laboratory conditions

The results of comparative seasonal biology studies of Banana leaf roller, Erionota torus Evans revealed, female skipper laid eggs in cluster on under side of the banana leaves. During rainy season, the incubation, total larval and pupal period ranged from 7-9 days, 26-33 days and 10-12 days, respectively. The total life cycle (egg to adult) varied between 52-67 days for male and 55-70 days for female. However, slight variation was observed during winter season with 7-10 days, 27-36 days and 11-13 days, respectively for incubation, larval and pupal period. The total life cycle (egg to adult) ranged from 55-72 days for male and 58-75 days for female.
Drug resistance of clinical and environmental isolates of Brucella species in Iran: a meta-analysis

Background: Brucellosis is a contagious and febrile disease endemic to Iran. Increased antibiotic resistance in endemic areas may lead to increased risk of treatment failure and the risk of disease relapse. This systematic review and meta-analysis was performed to determine the antibiotic susceptibility profiles of Brucella species isolated from clinical and environmental samples in Iran. Methods: Using national and international databases and extracted keywords from the MeSH database, a fully computerized search was done until 11 June 2018. Of 385 collected studies on the prevalence of drug resistance of Brucella species isolated in Iran, six articles were included in the meta-analysis using predefined eligibility criteria. Results: Overall resistance rates of Brucella species to different antibiotics in Iran were as follows: doxycycline: 0%, tigecycline: 5.1%, trimethoprim/sulfamethoxazole: 5.7%, ciprofloxacin: 2.7%, streptomycin: 5%, rifampin: 9.5%, tetracycline: 4.6%, gentamicin: 3.9%, moxifloxacin: 0%, erythromycin: 33.3%, azithromycin: 5.8% and ceftriaxone: 6.3%. Conclusion: Our study revealed that the prevalence of drug resistance of Brucella species isolated from clinical and environmental samples in Iran was acceptable and low. However, care should be exercised in the use of common antibiotics for the treatment of brucellosis to prevent the spread of drug resistance.
Dynamics of age-related catastrophic mitotic failures and recovery in yeast

Genome instability is a hallmark of aging and contributes to age-related disorders such as progeria, cancer, and Alzheimer’s disease. In particular, nuclear quality control mechanisms and cell cycle checkpoints have generally been studied in young cells and animals where they function optimally, and where genomic instability is low. Here, we use single cell imaging to study the consequences of increased genomic instability during aging, and identify striking age-associated genome missegregation events. During these events the majority of mother cell chromatin, and often both spindle poles, are mistakenly sent to the daughter cell. This breakdown in mitotic fidelity is accompanied by a transient cell cycle arrest that can persist for many hours, as cells engage a retrograde transport mechanism to return chromosomes to the mother cell. The repetitive ribosomal DNA (rDNA) has been previously identified as being highly vulnerable to age-related replication stress and genomic instability, and we present several lines of evidence supporting a model whereby expansion of rDNA during aging results in nucleolar breakdown and competition for limited nucleosomes, thereby increasing risk of catastrophic genome missegregation.
Genetic Diversity Analysis and F2 Population Development for Breeding of Long Juvenile Trait in Soybean

Genetic diversity analysis using molecular markers is an important step for selecting appropriate parents in a soybean breeding program. The aims of this study were to (1) analyze genetic diversity of 29 soybean genotypes assessed with 27 SSR markers for selecting appropriate parents and (2) develop F2 populations to be used for breeding long juvenile (LJ) trait in soybean tobe cultivated in short photoperiod condition. The soybean genotypes used consisted of 11 Indonesian soybean genotypes and 18 genotypes introduced from the USA. F2 populations were developed by crossing Grobogan with three introduced genotypes carrying LJ character. The PIC values of the 27 SSR markers ranged from 0.87 to 0.96. Cluster analysis resulted in three mainclusters at coefficient similarity of 0.76. The five LJ introduced accessions and the nine Indonesian genotypes showed high genetic distances and are useful as parent pairs for developing breeding populations. The F1 progeny phenotypicperformances of the cross far exceeded the performaces of both parents. Three F2 populations were developed by crossing the distantly related soybean genotypes. The F2 populations were verified by using SSR markers and it was found that they segregated in a 1:2:1 ratio confirming the segregation ratio of codominant SSR markers. The F2 populations should be useful for breeding LJ characters to improve soybean productivity in low latitude tropical countries such as Indonesia, which has day length of approximately 12 h all year round.
The effects of serotonin inhibitors on bone metabolism: literature review

Depression is a mood and behavior disorder. It is a very frequent pathology in the world that requires phar-macological treatment using drugs that inhibit the recovery of serotonin. In fact, serotonin is a hormone that creates a feeling of well-being at the level of central nervous system. Serotonin is mainly produced by nerve cells. Therefore, selective serotonin reuptake inhibitors (SSRIs) are mainly used for the treatment of states of anxiety and major depressive disorder. SSRIs increase serotonin level, blocking its resorption in the presynaptic cell. Consequently, an increase in the bioavailability of serotonin in the synaptic junction occur. In fact, at the bone level, according to some observations, it causes an increase in bone resorption. Our study with a systematic review of the literature was to evaluate whether the intake of SSRIs could in any way influence implant survival. “SSRI” and “dental implant” were used as key words in the principal resources. Five articles that met the inclusion criteria were considered. The study found that these drugs can affect the implant survival rate. The data of these articles concerning implant survival have extrapolated. There is an association between intake and implant survival, prob-ably due to a possible link between bone metabolism and drug. Further studies are recommended to effectively evaluate the influence of the drug on implant survival.
Biochemical, physiological and agronomic response of wheat to changing climate of rainfed Pakistan

Designing the adaptation strategies by studying biochemical, physiological and agronomic response of wheat to climate change will be important for ensuring yield stability and economic sustainability in future. The current study was conducted under three variable climatic sites of rainfed field Pothwar viz. Islamabad (Optimum climatic conditions), URF-Koont Chakwal (Moderate temperature and water stress) and Talagang (high temperature and water stress) under four sowing dates (SD1 = 21-30 Oct, SD2 = 11-20 Nov, SD3 = 01-10 Dec, and SD4 = 21-30 Dec during 2013-14 and 2014-15) and five wheat genotypes. The study quantified the biochemical, physiological and agronomic response of wheat under different treatments. Stress in the form of drought and unfavorable temperature resulted in increase of total soluble sugar content (TSSC), total soluble protein content (TSPC) proline and leaf membrane stability index (LMSI), while decrease in relative water content (RWC), leaf area (LA), plant height (PH), biological yield (BY) and grain yield (GY). Leaf gaseous exchange parameters i.e. net photosynthesis (An), intercellular CO2 concentration (Ci), transpiration rate (Tr) and stomatal conductance (gs) remained highest under optimum conditions as compared to stress while opposite trend was observed for stomatal resistance (rs). Correlation analysis among biochemical, physiological and agronomic traits showed that grain yield was positively correlated with RWC, LA, An, Ci, E, gs, SPAD, PH and BY while negatively correlated with all other parameters. These results suggested to change sowing dates based on prevailing climatic conditions and use of tolerant cultivar to have higher sustainable crop productivity.
Preventing or Concealing Organizational Misconduct? Corporate Boards in a Transitional Economy

This study seeks to understand the potential dark consequences of corporate boards on organizational misconduct in a transitional economy. Contrary to predictions from the agency theory, we find that outsider representation on the board is associated with an increased probability of misconduct in organizations that lack legitimacy in the early transitional period. Besides, the salience of board outsiders further enhances the positive relationship between outsider representation on the board and the likelihood of organizational illegality. We suggest that boards of directors may serve as window dressing for organizations lacking legitimacy in transitional economies. Such window dressing may create a circumstance that makes organizational misconduct possible in underdeveloped legal environments. This study suggests the importance of considering the potential dark side of adopting seemingly credible corporate governance structures in transitional economies.