Miracle-dz/UniFAR-FTUs huggingface dataset:
Sex-related differences and chronobiology of ST-elevation myocardial infarction: findings from a single hub center in Italy.

OBJECTIVE Type I acute myocardial infarction (AMI) is a life-threatening condition. Time of event and rescue procedures, and sex-specific differences may play a crucial role. We aimed to investigate chronobiological patterns and sex-specific differences in a cohort of AMI patients referred to a single hub center in Italy. PATIENTS AND METHODS We considered all patients consecutively admitted for AMI (STEMI) to the Hospital of the Heart, in Massa, Tuscany (a region of Italy), between 2006 to 2018, who underwent interventional procedures. Sex, age, time of hospital admission, outcome (discharged alive/deceased), main comorbidities, and time between symptom onset and emergency medical service (EMS) activation, were analyzed. Chronobiologic analysis was applied according to hour of day, month, and season of the year. RESULTS Overall 2,522 patients (mean age 64.6±13.1 years, 73% males) were considered. In-hospital death (IHM) occurred in 96 subjects (3.8%). At univariate analysis, deceased subjects were more likely to be female, older, with longer wait for EMS activation and with interventional procedures during night-time. The multivariate analysis identified female sex, age, history of ischemic heart disease, and night-time interventional procedure as independently associated factors to IHM. Chronobiologic analysis showed a pattern with a main morning peak for total sample, males, and females (p=0.00027; p=0.0006); p=0.0121, respectively). Events showed a higher peak in summer, with no differences by sex, but IHM was higher in winter. Females showed a higher delay for EMS activation, compared to males (p<0.001), but with no effects on prognosis. On the contrary, males with a delay showed higher mortality. CONCLUSIONS Great effort should be spent to reduce patient-related delays in interventional procedures, being this issue crucial in both sexes.
High‐temperature diamond‐anvil pressure cell for single‐crystal studies

The miniature, single‐crystal, diamond‐anvil pressure cell of Merrill and Bassett [Rev. Sci. Instrum. 45, 290 (1974)] has been adapted for x‐ray crystallographic studies at sustained temperatures and pressures up to 450 °C at 30 kbar.
Amplitude Equations for Systems with Competing Instabilities

We describe how to derive ordinary differential equations to predict the time dependence of a system governed by partial differential equations when that system is near to the polycritical condition for the onset of several instabilities. The method is illustrated for the general case of two competing instabilities and then a specific physical example of this case is worked out in detail. The basic idea is to extend the Krylov–Bogolyubov–Mitropolsky method of nonlinear mechanics to bifurcation problems.
An Energy Analysis of Amplitude Death of a Pair of Oscillators With Delayed Coupling

This paper presents an energy analysis of the amplitude death, a phenomenon that the individual oscillators cease to oscillate when coupled and go to an equilibrium motion instead, of a pair of coupled oscillators with time delay that are slightly perturbed from two undamped oscillators and with delayed coupling. The energy analysis reveals that amplitude death, as well as the stability of the phase-locked periodic solutions, can be justified by the sign of the averaged total powers along a special function with harmonic entries, rather than along arbitrary solution of the coupled oscillators as in the application of the method of Lyapunov’s function for stability analysis. An illustrative example is given to show the effectiveness of the present method.Copyright © 2005 by ASME
Robots in Assisted Living Facilities: Scoping Review

Background Various technological interventions have been proposed and studied to address the growing demand for care of residents in assisted living facilities, in which a preexisting shortage of professional caregivers has been exacerbated by the COVID-19 pandemic. Care robots are one such intervention with the potential to improve both the care of older adults and the work life of their professional caregivers. However, concerns about efficacy, ethics, and best practices in the applications of robotic technologies in care settings remain. Objective This scoping review aimed to examine the literature on robots used in assisted living facilities and identify gaps in the literature to guide future research. Methods On February 12, 2022, following the PRISMA-ScR (Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews) protocol, we searched PubMed, CINAHL Plus with Full Text, PsycINFO, IEEE Xplore digital library, and ACM Digital Library using predetermined search terms. Publications were included if they were written in English and focused on the use of robotics in assisted living facilities. Publications were excluded if they did not provide peer-reviewed empirical data, focused on user needs, or developed an instrument to study human-robot interaction. The study findings were then summarized, coded, and analyzed using the Patterns, Advances, Gaps, Evidence for practice, and Research recommendations framework. Results The final sample included 73 publications from 69 unique studies on the use of robots in assisted living facilities. The findings of studies on older adults were mixed, with some studies suggesting positive impacts of robots, some expressing concerns about robots and barriers to their use, and others being inconclusive. Although many therapeutic benefits of care robots have been identified, methodological limitations have weakened the internal and external validity of the findings of these studies. Few studies (18/69, 26%) considered the context of care: most studies (48/69, 70%) collected data only on recipients of care, 15 studies collected data on staff, and 3 studies collected data on relatives or visitors. Theory-driven, longitudinal, and large sample size study designs were rare. Across the authors’ disciplines, a lack of consistency in methodological quality and reporting makes it difficult to synthesize and assess research on care robotics. Conclusions The findings of this study call for more systematic research on the feasibility and efficacy of robots in assisted living facilities. In particular, there is a dearth of research on how robots may change geriatric care and the work environment within assisted living facilities. To maximize the benefits and minimize the consequences for older adults and caregivers, future research will require interdisciplinary collaboration among health sciences, computer science, and engineering as well as agreement on methodological standards.
Untangling the systematic dilemma behind the roughskin spurdog Cirrhigaleus asper (Merrett, 1973) (Chondrichthyes: Squaliformes), with phylogeny of Squalidae and a key to Cirrhigaleus species

Cirrhigaleus comprises a small genus of rare barbel-bearing dogfish sharks with distributions in limited regions of all oceans. Generic validity and taxonomic status of some species are upon controversies by morphological and molecular evidence that often suggest reallocation of Cirrhigaleus species into the genus Squalus. Particularly, the roughskin spurdog C. asper exhibits intermediary morphological characteristics within Squalidae that requires clarification. In the present study, a phylogenetic approach was undertaken to test the correct generic placement of C. asper using novel and revised morphological characters. We performed maximum parsimony analysis of 51 morphological characters of the internal (e.g., neurocranium, clasper cartilages, pectoral and pelvic girdles) and external anatomy applied to 13 terminal taxa. Cirrhigaleus represents a valid genus and it is supported by eight synapomorphies: high number of monospondylous vertebrae; medial nasal lobe supported by fleshy core and innervated by the buccopharyngeal branch of the facial nerve; neurocranium with greatest width across nasal capsules; one facet and one condyle in the puboischiadic bar for articulating with the basipterygium; two intermediate segments between the basipterygium of the pelvic fin and the axial cartilage of the claspers; five terminal clasper cartilages; and posterior medial process of the puboischiadic bar absent. Cirrhigaleus asper is sister-species to a small clade comprising C. barbifer and C. australis which is supported by one synapomorphy, presence of conspicuous cusplets in the dermal denticles. Cirrhigaleus barbifer, C. asper and C. australis are redescribed herein and the neotype of C. barbifer is designated. A key to Cirrhigaleus species is also given and the inner relationships within Squalus is tentatively discussed.
Blobs and front propagation in the scrape-off layer of magnetic confinement devices

In this paper we show the self-consistent evolution of an isolated density perturbation in models of tokamak scrape-off layer turbulence. Our purpose is to explain the possible mechanisms responsible for radial propagation of density perturbations observed in the scrape-off layer. Results of both two-dimensional numerical simulations and one-dimensional quasilinear modeling of the propagative events are presented, and shown to be consistent with many experimental observations. The role of sheath dissipation for front propagation and turbulent mixing is also addressed.
Band gap engineering of TiO2 through hydrogenation

The band gap of rutile TiO2 is reduced remarkably through high-temperature annealing in hydrogen atmosphere, and the absorption of visible light of the hydrogenated-TiO2 can be enhanced. These modifications of hydrogenated-TiO2 become more evident with the increase in annealing hydrogen pressure. A defect band arises near the valence band upon hydrogenation while the conduction band remains almost unchanged, which helps for meeting the requirements for hydrogen production through water splitting. This method could be also indicative for the band gap adjustment of other oxide semiconductors.
Investigation of the dual-task performance and affecting factors in female patients with fibromyalgia syndrome

ABSTRACT Recent studies report that dual-task (DT) performance might be affected in patients with fibromyalgia syndrome (FMS). This cross-sectional study aims to compare the DT performance in female patients with FMS and healthy controls, and to investigate the DT-related factors in these patients. This study was conducted at a university hospital between November 2021 and April 2022. Forty females aged 30–65, diagnosed with FMS, and 40 aged-matched pain-free healthy controls were included. All participants performed the Timed Up and Go Test under a single task (ST) and a cognitive DT condition, and the DT cost was calculated. The following evaluations were applied; The six-minute walk test, Baecke Habitual Physical Activity Questionnaire, Multidimensional Fatigue Inventory-20, Toronto Alexithymia Scale, Trail Making Test, and the Revised Fibromyalgia Impact Questionnaire. As a result of the study, the patient group showed lower performance than controls in both, ST and DT conditions (p < .05). Disease duration, pain and fatigue severity, functional capacity, leisure time and physical activity total scores, alexithymia scores, health status, and cognitive variables were correlated with DT performance in the patient group (p < .05). According to our results, we consider that the rehabilitation approach for females with FMS should take into account DT and related characteristics.
The effect of body awareness on trunk control, affected upper extremity function, balance, fear of falling, functional level, and level of independence in patients with stroke

ABSTRACT Objectives This study was conducted to examine the effects of body awareness on trunk control, affected upper extremity function, balance, fear of falling, functional level, and level of independence in patients with stroke. Methods 35 individuals between the ages of 21 and 78 who were diagnosed with stroke were included in the study. The body awareness of the individuals participating in the study was determined with the Body Awareness Questionnaire (BAQ), trunk control with Trunk Impairment Scale (TIS), the affected upper extremity functions with Motor Activity Log-28 (MAL,-28), and Fugl-Meyer Upper Extremity Assessment (FMUEA), balance with Berg Balance Scale (BBS), fear of falling with Tinetti Falls Efficacy Scale (TFES), functional level with Barthel Activities of Daily Living Index (BI) and level of independence with Functional Independence Measures (FIM). Results For patients participating in the study, 26% were female, 74% were male and 43% showed left, 57% showed right hemisphere involvement. In simple linear regression analysis, BAQ measurement had a statistically significant effect on TIS (F = 25.439 p = 0.001), MAL-28 (F = 7.852 p = 0.008), FMUEA (F = 12.155 p = 0.001), BBS (F = 13.506 p = 0.001), TFES (F = 13.119 p = 0.001), BI (F = 19.977 p = 0.001) and FIM (F = 22.014 p = 0.001) in patients with stroke. Conclusions In conclusion, body awareness was found to be one of the factors affecting trunk control, affected upper extremity function, balance, fear of falling, functional level, and level of independence in patients with stroke. It was thought that there was a need for assessment of body awareness and include bodyawareness in rehabilitation programs in patients with stroke.
The epidemiology and disease pattern of pediatric ocular morbidities in Western India: The National Institute of OphthalMology AmBlyopia StUdy in Indian Paediatric EyeS (NIMBUS) study report 1

Purpose: To determine the pattern of pediatric ocular morbidities in western India. Methods: This was a retrospective longitudinal study that included all consecutive children aged ≤15 years who presented to the outpatient department of a tertiary eye center for the first time. Patient demographics, best-corrected visual acuity (BCVA), and ocular examination data were compiled. Subgroup analysis was also performed based on age group (years): ≤5, 5–10, and >10–15. Results: A total of 11,126 eyes of 5563 children were included in the study. The mean age of the study population was 5.15 (±3.32) years with males (57.07%) being predominant. Approximately half of the patients (50.19%) were under the age of 5 years, followed by those aged 5–10 years (45.1%) and >10–15 years (4.71%). Among the study eyes, the BCVA was ≥20/60 in 58.57%, indeterminable in 35.16%, and <20/60 in 6.71%. The commonest ocular morbidity noted was refractive error (28.97%) followed by allergic conjunctivitis (7.64%) and strabismus (4.95%) in the total study cohort and also after age stratification. Conclusion: Refractive error, allergic conjunctivitis, and strabismus are the major causes of ocular morbidity in pediatric eyes at a tertiary care center. Planning screening programs at the regional and national levels is crucial to decreasing the burden of eye disorders. These programs also need to have a suitable referral mechanism established and be smoothly connected to primary and secondary health-care centers. This will help to assure quality eye care delivery, while also reducing the strain of overworked tertiary centers.
Prevalence of and risk factors for overweight among adolescents of a sub-metropolitan city of Nepal

Background Overweight is a global public health problem with increasing trend especially in middle to lower socioeconomic country like Nepal. The nutritional status of adolescents being shaped by socio-cultural, environmental, and economic factors has also been impacted by their food habits and level of physical activity. The current nutritional shift and rapid urbanization had emerged overweight as an additional burden for consistently prevalent undernutrition issues. So, the study aimed to identify the prevalence of and risk factors for overweight among school adolescents. Methods A cross-sectional analytical study was carried out among random sample of 279 adolescents from nine schools of a Sub-metropolitan city of Nepal. The anthropometric measurement of the height and the weight were taken as per the standard. The odds ratio with a 95% CI was calculated and a p-value of ≤0.05 was considered as cut off for statistical significance by fitting into the final multivariable logistic regression. Results The overall prevalence of overweight was obtained as 9.31% (95% CI: 6.40–13.3). The early aged adolescents were more overweight than compared to middle-aged adolescents (AOR: 0.27, CI: 0.028–2.67) and late adolescents (AOR: 0.66, CI: 0.068–6.44) respectively. Similarly, adolescents residing in rural areas had 0.35 (AOR = 0.33, CI: 0.030–3.71) odds of being overweight compared to their counterparts. Adolescents with sedentary behavior were about 4 times (AOR = 3.51, CI: 0.79–15.54) more likely of being overweight than their counterparts. Conclusion Overweight among adolescents residing in urban areas has emerged as an alarming issue due to their unhealthy lifestyle habits. It is therefore pertinent to emphasize adolescents to maintain healthy weight status through health food habits and physical activity.
Effect of age on wingbeat frequency of Aedes aegypti and potential application for age estimation of mosquitoes

To combat mosquito‐borne diseases, a variety of vector control tools have been implemented. Estimating age structure in populations of vector species is important for understanding transmission potential. Age‐grading techniques have been used as critical methods for evaluating the efficacy of vector control tools. However, methods like mark‐release‐recapture and ovarian dissection are laborious and require a high level of training. For decades, scientists have discussed the wide array of acoustic signatures of different mosquito species. These distinguishable wingbeat signatures with spatiotemporal classification allow mosquitoes of the same species to locate one another for mating. In recent years, the use of sensitive acoustic devices like mobile phones have proved effective. Wingbeat signatures can be used to identify mosquito species without the challenge of intensive field collections and morphological and molecular identifications. In this study, laboratory Aedes aegypti (L.) female and male wingbeats were recorded using mobile phones to determine whether sex and age differences with chronological time, and across different physiological stages, can be detected. Our results indicate significantly different wingbeat signatures between male and female Ae. aegypti, and a change of wingbeat frequencies with age and reproduction stage in females.
The influence of anatomic stage and receptor status on first recurrence for breast cancer within 5 years (AFT‐01)

Risk‐stratified follow‐up guidelines that account for the absolute risk and timing of recurrence may improve the quality and efficiency of breast cancer follow‐up. The objective of this study was to assess the relationship of anatomic stage and receptor status with timing of the first recurrence for patients with local‐regional breast cancer and generate risk‐stratified follow‐up recommendations.
Chromatic Strengths of Colors, Part II. The Munsell System

An approximate model of the Munsell color space in terms of dominant wavelength and colorimetric purity is described. This approximation space describes the Value and Chroma relations as functions of chromaticity and the Chroma relations as a function of colorimetric purity, but does not describe the Hue spacing. A single curve describes (approximately) the chromaticities in all Chroma circles and this curve is the same as that describing the threshold between those colors which appear to contain gray and those that appear to be fluorescent (G0) as described in Part I. The loci of the G0 colors and of colors with constant gray content are also described for the approximation space.
Assembly and regulation of the mammalian mRNA processing body

Messenger RNA processing bodies (P-bodies) are cytoplasmic membrane-free organelles that contain proteins involved in mRNA silencing, storage and decay. The mechanism by which P-body components interact and the factors that regulate the stability of these structures are incompletely understood. In this study, we used a fluorescence-based, two-hybrid assay to investigate interactions between P-body components that occur inside the cell. LSm14a, PATL1, XRN1, and NBDY were found to interact with the N-terminal, WD40-domain-containing portion of EDC4. The N-terminus of full-length PATL1 was required to mediate the interaction between EDC4 and DDX6. The C-terminal, alpha helix-domain- containing portion of EDC4 was sufficient to mediate interaction with DCP1a and CCHCR1. In the absence of endogenous P-bodies, caused by depletion of LSm14a or DDX6, expression of the portion of EDC4 that lacked the N-terminus retained the ability to form cytoplasmic dots that were indistinguishable from P-bodies at the level of UV light microscopy. Despite the absence of endogenous P-bodies, this portion of EDC4 was able to recruit DCP1a, CCHCR1 and EDC3 to cytoplasmic dots. The results of this study permit the development of a new model of P-body formation and suggest that the N-terminus of EDC4 regulates the stability of these structures.
Ethical reasoning and participatory approach towards achieving regulatory processes for animal-visitor interactions (AVIs) in South Africa

South Africa’s wide range of animal facilities offers many different types of Animal-Visitor Interactions, wild animal encounters where animals and visitors come closer than in normal circumstances. The aim of this study was to provide a map of the ethically relevant aspects involved in AVIs in South Africa as a first step towards regulating these activities. A participative approach based on the ethical matrix, a tool which organizes the ethical standings of the stakeholders by three bearing ethical principles (wellbeing, autonomy, fairness), was applied. The matrix was populated through a top-down approach and refined by engaging stakeholders in a workshop and two online self-administrated surveys. The outcome is a map of the value demands concerning Animal Visitor Interactions. This map shows how the ethical acceptability of AVIs is linked to different relevant issues like animal welfare, education, biodiversity conservation, sustainability, human competency, facility mission, impact on scientific research and socio-economic outcomes. In addition, results highlighted the importance of cooperation among stakeholders and suggested that attention for animal welfare can inform decision making and inspire a multidisciplinary approach in implementing a regulatory frame for South African wildlife facilities.
Fear and anxiety differ in construal level and scope

ABSTRACT The fear-anxiety distinction has been extensively discussed and debated among emotion researchers. In this study, we tested this distinction from a social-cognitive perspective. Drawing on construal level theory and regulatory scope theory, we examined whether fear and anxiety differ in their underlying level of construal and scope. Results from a preregistered autobiographical recall study (N = 200) that concerned either a fear situation or an anxiety situation and a large dataset from Twitter (N = 104,949) indicated that anxiety was associated with a higher level of construal and a more expansive scope than fear. These findings support the notion that emotions serve as mental tools that deal with different challenges. While fear prompts people to seek immediate solutions to concrete threats in the here and now (contractive scope), anxiety prompts them to deal with distant and unknown threats that require more expansive and flexible solutions (expansive scope). Our study contributes to a growing literature on emotions and construal level and points to interesting avenues for further research.