Miracle-dz/UniFAR-FTUs huggingface dataset:
Role of Vitamin B Complex as an Add-on Therapy to Diclofenac in Patients with Primary Osteoarthritis of the Knee

Objective: This study was conducted with the aim to evaluate the efficacy and safety of Vitamin B complex as an add-on therapy to diclofenac in patients with primary osteoarthritis (OA) of the knee. Materials and Methods: In this prospective, open-labeled, randomized, and comparative clinical study, a total of 130 patients of age >40 years with primary OA of knee attending orthopedics OPD were randomly allocated into two groups of 65 each, i.e., Group D and Group B. In Group D, patients received tablet diclofenac 75 mg and in Group B, patients received tablet Vitamin B complex along with diclofenac once daily for 4 weeks, respectively. Clinical assessment was done at baseline and at the end of 4 weeks and 8 weeks by the visual analog scale (VAS), WOMAC index, and Lequesne index. Results: During the intergroup comparison, it was found that Vitamin B complex as an add-on therapy to diclofenac produced statistically significant reduction in mean VAS pain score (P < 0.05). However, the difference in mean WOMAC index and Lequesne index was not statistically different at 4 and 8 weeks between the two groups (P > 0.05). Mild side effects were seen at 4 weeks, but no side effects persisted up to 8 weeks in both the groups. Conclusion: The present study suggested that Vitamin B complex as an add-on therapy was found to cause a significant reduction in pain score. It could be a promising drug in patients with OA to improve the analgesic effect, when combined can reduce the dose of diclofenac, thereby minimizing the side effects.
Electrophysiological Evaluation of Audiovestibular Pathway Dysfunction in Parkinson's Disease and Its Correlates: A Case Control Study

Background: Parkinson's disease (PD) is associated with brainstem dysfunction causing non-motor symptoms. Vestibular evoked myogenic potential (VEMP) and brainstem auditory evoked potential (BAEP) are electrophysiological tests to assess the vestibular and auditory pathways in the brainstem. Objectives: To study the abnormalities of cervical VEMP (cVEMP) and BAEP in PD and to correlate the findings with the symptoms related to brainstem involvement. Patients and Methods: cVEMP and BAEP were recorded in 25 PD patients and compared 25 age matched controls. The PD patients were assessed with the following clinical scales: REM Sleep Disorder Screening Questionnaire (RBD-SQ), Epworth Sleepiness Scale (ESS), mini-BESTest, Geriatric Depression Scale (GDS-15) and MMSE (Mini-mental state examination). The P13 and N23 peak latencies and the P13/N23 amplitude of cVEMP, the latencies of waves I, III and V, and the inter-peak latencies (IPL) of waves I-III, III-V and I-V of BAEP were measured. Results: The PD patients showed prolonged latencies and reduced amplitude in cVEMP responses. They had abnormal BAEP in the form of prolonged absolute latencies of wave V, followed by wave III and I–V IPL with no significant difference in waves I and I–III IPL. The cVEMP abnormality was correlated directly with RBD-SQ and inversely with mini-BESTest scores. There were no correlations between cVEMP/BAEP abnormality and disease severity, GDS-15, ESS and MMSE. Conclusion: PD is associated with cVEMP and BAEP abnormalities that suggest auditory and vestibular pathway dysfunction in the brainstem and cVEMP correlates with the symptoms of brainstem degeneration like RBD and postural instability.
Monday Blues - Rare Cause of Hypoglycemia in a Child with Leukemia

Hypoglycemia in a child with acute lymphoblastic leukemia (ALL) often makes the clinician think of sepsis or metabolic disturbances due to relative adrenal insufficiency with steroid withdrawal. We report a rare scenario of drug-induced hypoglycemia in a child on treatment for ALL. Recurrent symptomatic episodes of hypoglycemia in a 4-year-girl on treatment for high-risk ALL were analyzed and it was surprising to note that the episodes were noted on early hours on Monday and Sunday nights. Detailed evaluation for the etiology and the workup was not contributory. With the background of drug history for ALL maintenance and occurrence of episodes on Mondays, possibility of drug-induced hypoglycemia secondary to cotrimoxazole was considered. Dose alteration for trimethoprim-sulfamethoxazole was considered stopping the drug is not feasible. Malnutrition was attributed as the coexisting risk factor in our child.
Assessment of influencer’s effects on customers’ online purchasing behavior in Vietnam

Today, the development of the Internet and social networks has changed the lives of human beings. The ability of these technologies to connect people in real-time expands the influence of some people in the community. Therefore, this study is conducted to test whether customers change purchasing behavior in online environments under the impact of those influencers by using Technology Acceptance Model (TAM). The study conducted a survey of 503 Vietnameses on Google Form from November 2020 to mid-January 2021. The collected data were analyzed using AMOS 24 with CB-SEM analysis method. The results showed a positive relationship between influencers and customers’ online purchasing behavior. More specifically, customers are more likely to buy online if they trust influencers and their advertisements. This is the most influential factor among the three influencer traits (as source credibility): trustworthiness, expertise, and attractiveness. A remarkable point in this study is that Vietnamese people are more concerned with perceived ease of use when buying online than other factors in the TAM model. This is the basis for businesses to implement influencer marketing strategies and improve the competitiveness of their online business.
Investigation of gastrintestinal parasites in rabbits of the species Oryctolagus cuniculus in the Northwest region of São Paulo, Brazil

Enteroparasites can be pathogenic for the rabbit population and for this reason, we have investigated its occurrence in bioterium of rabbits. The sample group was composed of 103 adult males of the species Oryctolagus cuniculus and New Zealand breed. Fecal samples (n = 103) were processed using the Willis Techniques (Fluctuation in saturated sodium chloride solution with specific density of 1.20 g/mL) and Faust (Centrifugal-flotation in zinc sulphate with density of 1.18 g/ml). The diameters of larger and smaller sizes of the sporocysts and sporozoites of the coccidia were measured by means of optical microscopy using the program CellSens 1. 17_00_en_Rhine_13Feb2017. The Faust Technique showed positivity of 39.74% (31/78) for Eimeria spp, while in Willis Technique, 35.90% (28/78) was observed for Eimeria spp, being the species Eimeria perforans and in 51.28% (47/78) of them there was no parasitism. We identified, for the first time, the occurrence of the specie E. perforans in rabbits of the species O. cuniculus, New Zealand breed kept in a bioterium. Therefore, it is extremely important for the implantation of parasitic control of rabbits kept in bioterium for scientific purposes, the monitoring of possible infections by means of periodic coproparasitological exams.
Access to and Documentation of Publicly Financed Survey Data

The topic of this paper is access to and documentation of survey data financed through public funds. We distinguish between four types of publicly financed survey data: (1) Academic survey data from the national or international research infrastructures; (2) data from DFG projects or similarly funded projects; (3) survey data collected in research projects funded by the Federal State and the Lander (Ressortforschung); (4) Population and Household surveys from national and international statistical agencies. For each of these types of data we describe the current situation and present recommendations for future developments.
AP-COMJ210012 1..10

Object affordances play a major role in action expression: (a) providing opportunities to generate potential solutions to instrumental problems and (b) shaping and constraining the motor actions available to an individual. The playful manipulation of objects can facilitate individual acquisition of functional object-assisted actions through affordance learning. We tested the “object affordance” hypothesis in free-ranging long-tailed macaques. This hypothesis holds that the physical properties associated with stone size afford different stone-directed actions, in the context of stone handling (SH) behavior, a form of culturally maintained stone play from which stone tool use can emerge. We predicted that higher SH versatility (i.e., total number of different SH behavioral elements expressed) and higher duration of the SH behavioral element “Pound” would be associated with the manipulation of medium-sized stones, followed by small stones, and then large stones. Our data partly supported these predictions. Both medium-sized and small-sized stones afforded the highest SH versatility, and a higher duration of “Pound” than large stones. As expected, duration of “Pound” was higher with medium than small stones, but the difference was not statistically significant. Our results were consistent with Newell’s constraint model, which emphasizes the role of objects’ physical properties in limiting and enhancing the expression of actions directed to these objects. The relaxed selective pressures acting on SH behavior may enhance the expression of a range of actions directed toward stones of different sizes that could facilitate the emergence of instrumental solutions and may contribute to explaining the evolution of lithic technology in early humans.
Give Text A Chance: Advocating for Equal Consideration for Language and Visualization

Visualization research tends to de-emphasize consideration of the textual context in which its images are placed. We argue that visualization research should consider textual representations as a primary alternative to visual options when assessing designs, and when assessing designs, equal attention should be given to the construction of the language as to the visualizations. We also call for a consideration of readability when integrating visualizations with written text. In highlighting these points, visualization research would be elevated in efficacy and demonstrate thorough accounting for viewers’ needs and responses.
Outcome of Fracture Distal Femur Treated with Intramedullary Interlocking Nailing

Objective: To evaluate the functional and radiological outcome of the distal femur fracture treated with a retrograde locking nail. Methods: This is a descriptive study conducted at the Orthopedic department Dibba Hospital Fujairah, United Arab Emirates for one-year duration from March 2019 to March 2020. All patients who met the inclusion criteria were treated with femoral retrograde nailing technique. The postoperative functional score was assessed according to Schatzker and Lambert criteria, which were rated excellent, good, and poor. Radiological union was assessed by X-rays. Results: There were 103 patients with a mean age of 35.20 ± 10.66 (range, 20 to 50 years). There were 78 men (75.72%) and 25 women (24.27%). Most of the fractures (68.9%, n = 71) were caused by car accidents. Fracture of the right side occurred in 70 (67.96%) patients, and the left side fracture in 33 (32.03%) patients. Excellent results were obtained in 75 (72.81%) patients and good results were obtained in 28 patients (28.20%). The nonunion has been documented in one patient. Conclusion: Excellent and good functional and radiological results were obtained in patients with distal femur treated with retrograde locking nails. For some distal femoral fractures, we recommend the use of a retrograde locking nail.
Experimental analysis and uncertainty quantification using random sampling technique for ADS experiments at KUCA

ABSTRACT Nuclear data-induced uncertainties of neutronics parameters (neutron multiplication factor keff, one-point kinetics parameters and prompt neutron decay constant α) are quantified for lead-bismuth zoned accelerator-driven system experiments at the Kyoto University Critical Assembly, in order to contribute validation for subcritical core analysis. The random sampling technique using SCALE6.2. 1/Sampler/NEWT/PARTISN is utilized for the validation and the uncertainty quantification, because the random sampling technique is applicable for a problem which is not easy to apply the perturbation theory. Consequently, it is confirmed that the numerical results of α reasonably agree with the experimental ones, compared with the nuclear data-induced uncertainties. In addition, it is clarified that the nuclear data-induced correlations between α and keff and between α and neutron generation time Λ are strongly negative and positive, respectively. This fact implies that the numerical predictions of keff and Λ can be improved by the data assimilation technique using subcritical experimental results of α, which can be directly measured even for a deep subcritical system.
American Journal on Intellectual and Developmental Disabilities Examining Phenotypic Differences in Gaze Avoidance Between Autism and Fragile X Syndrome

We examined potential phenotypic differences in eye gaze avoidance exhibited by boys with autism spectrum disorder (ASD) and boys with fragile X syndrome (FXS). In Study 1, the Eye Contact Avoidance Scale (ECAS) was administered to caregivers of boys aged 7-18 years with FXS (n=148), ASD (n=168), and mixed developmental disabilities (MDD; n=128). In Study 2, subsets of boys with FXS (n=31) and boys with ASD (n=25) received a brief behavioral treatment probe to improve eye contact. Results showed that boys with FXS obtained significantly higher scores on the ECAS compared to boys with ASD and MDD. Exposure to the brief behavioral treatment probe resulted in significant decreases in scores for boys with FXS, but not for boys with ASD.
Distribution and Diversity of Macrobenthos in Sangu River, Bangladesh

This study was conducted to understand the macrobenthos distribution and abundance in Sangu River to monitor the aquatic pollution level. Both surface and sub-surface water and benthic sediments were collected from three stations of the Sangu River. A few indices viz. Shannon-wiener, Simpson, Margalef’s and Evenness were used to estimate the macrobenthic assemblages. In this study, a total of 11 major taxa comprising total 870 macobenthic species were identified. Shannon-wiener index was maximum (1.58) at lower part (LP) which indicated moderate to heavily pollute aquatic environment of the Sangu River. The average diversity values of Shannon, Evenness, Simpson and Margalef’s indices were 0.97, 0.43, 0.39 and 1.54 respectively. The concentration of dissolved oxygen was the lowest (4.90 mg/L) at LP and the highest (5.08 mg/L) at upper part (UP). This study showed that macrobenthos abundances was influenced by higher temperature, salinity, and pH. The percentage of organic carbon content was maximum (98.18%) at LP where the macrobenthic abundance was 330 individuals/m2, whereas it was minimum (80.77%) at UP where macrobenthic abundance was 248 individuals/m2 that indicated carbon content also influence the assemblages of the macrobenthos in the Sangu River. A clear gradient of physico-chemical and benthic soil parameters fluctuation was also found to be responsible for the variations of macrobenthos assemblage in the Sangu River. The Dhaka University Journal of Earth and Environmental Sciences, Vol. 9(2), 2020, P 27-34
Effect of treatment with trypanocides on Trypanosoma brucei induced oxidative stress and antioxidant enzyme activities in dogs

Oxidative stress and alteration of endogenous antioxidant enzymes play roles in the pathophysiological mechanism of trypanosomosis. The oxidative stress marker: malondialdehyde- MDA and antioxidative stress markers: Serum catalase- CAT, Serum Reduced Glutathione -GSH-Rd and Serum Superoxide dismutase- SOD of Nigerian local dogs (NLD) experimentally infected with Trypanosoma brucei were evaluated after treatments with diminazene aceturate (DA) and isometamidium chloride (IMC). Twenty dogs of age 3 – 4 months were assigned to any of the four groups of five dogs each as follows: 1 = infected and treated with DA (7.0 mg/kg); 2 = uninfected untreated; 3 = infected and untreated; 4 = infected and treated with IMC (0.5 mg/kg). DA and IMC cleared the parasites from the blood, following treatment of the dogs. Relapse was recorded in two dogs in group 1 and one dog in group 4 on days 35 and 56 post-infection (PI) respectively. No dog died except one in group 1. The levels of malondialdehyde- MDA increased significantly by day 7 post-infection in all the infected groups. However, by day 14 post-infection the malondialdehyde levels in group 4 became similar with group 2. The MDA level in group 1 remained significantly higher than in group 2. As from days 7 – 14 post-infection Catalase, Reducedg glutathionend superoxide dismutase levels in the infected groups were significantly lower than group 2. Nevertheless, both trypanocides did not return the levels of CAT, GSH, and SOD to pre-infection values before the termination of the experiment. The findings suggested that the two trypanocides could neither reverse the induced oxidative stress nor normalize the antioxidant capacity of the dogs infected with T. brucei.
The Relationship Between Workload and Burnout Among The Medical Staff In Hospital

Prolonged occupational stress can lead to the syndrome of job burnout. Workload was one of the factors that can cause the burnout. The main objective of this study was to determine the levels of job burnout and their relationships with workload among the medical staff. The key roles of medical staff in a hospital can be broadly separated into four areas which were the doctors, nurses, allied health professionals and support staff. Eighty medical staff from hospital volunteered to participate in this research. Different data were gathered using the Maslach Burnout Inventory (MBI), NASA-Task Load Index and Demographic questionnaire. The significance of the study was to investigate the relationship between the job burnout and workload among the medical staff in hospitals. The overall level of workload and job burnout was moderate. The results indicated that workload and job burnout among medical staff in hospitals was at moderate level. There was a significant relationship between workload and job burnout in this research.
Evaluating heat stress tolerance and molecular relationship among inbred lines of maize during early generations

Heat stress is one of abiotic stress that has deleterious effects on crops yield. Therefore, this study aims are to evaluate heat-tolerant maize lines and characterizing them by DNA molecular markers. Inbred lines were generated for two generations by selfing pollination. They were evaluated in each generation for the performance of some agro-morphological traits under normal and heat stress conditions. All the traits of the S1 and S2 inbred lines varied significantly among them under both conditions, except plant height was not significant under heat stress for the S1 lines. The L6 inbred line had the highest yield under the stress conditions in both S1 and S2 generations. Moreover, the heat susceptible index showed that the lines, L6 and L40 were the highest tolerant in the both generations. Furthermore, cluster analysis based on morphological traits for the 5 selected S2 inbred lines could be able to isolate the worst S2 inbred line under heat stress conditions in an independent cluster. In addition, they were characterized by ISSR and SRAP molecular markers. The ISSR detected higher polymorphism (79.79%) than SRAP marker (58.46%). The ISSR clustering patterns managed to classify the highest yield line (L6) under the heat stress in a separated cluster, but both the SRAP and combined isolated the worst line (L32) in one cluster. The Mantel’s test showed a positive correlation among all the studied markers. Additionally, the correlation was significant and highly strong (r=0.915) between morphological traits under normal conditions and SRAP marker. However, the identified S2 inbred lines with resistance to heat tolerance could be a beneficial source in the development of heat-tolerant maize hybrids.
A Prospective Randomized Study of the Safety and Efficacy of Transforaminal Lumbar Interbody Fusion Versus Posterior Lumbar Interbody Fusion in the Treatment of LumbarSpondylolisthesis: A Cost utility from a Lower-middle-income Country Perspective and Review of Literature

BACKGROUND: The safety and efficacy of transforaminal lumbar interbody fusion (TLIF) and posterior lumbar interbody fusion (PLIF) in lumbar spondylolisthesis have not been validated in many prospective randomized trials. AIM: We aimed to validate the safety and efficacy of TLIF and PLIF surgery in lumbar spondylolisthesis using the clinical, radiographic, and cost-utility outcomes. METHODS: The data of surgically treated single-level spondylolisthesis patients were randomized prospectively into two groups. The groups were compared regarding demographics, perioperative complications, hospital stay, total expenditure, fusion rate, and clinical outcomes (visual analog scale, Oswestry disability index, Zurich claudication scale, and Odom’s criteria). A review of literature was done to compare the outcomes with the ones from higherincome nations. RESULTS: Thirty-three patients underwent prospective randomization. The improvement in the clinical outcomes at 12-month follow-up showed improvement in the TLIF group more than the PLIF group but with no significant difference. The mean operative time was significantly longer in the PLIF (p < 0.05), also, the blood loss was significantly less in the TLIF (p < 0.001). The complications frequency did not show any statistical significance between both groups and no significant difference in the patient’s post-operative patient satisfaction (p = 0.6). The mean hospital stay was non-significantly longer in the PLIF (p = 0.7). At 12-month follow-up, 93.3% of the TLIF patients were fused versus 86.7% of the PLIF (p = 0.5). The total cost of the TLIF was significantly less (p < 0.001). CONCLUSION: Both PLIF and TLIF could achieve similar fusion rates and clinical satisfaction in the management of lumbar spondylolisthesis. The TLIF group was significantly better in terms of financial burden, operative time, and blood loss. Edited by: Ksenija Bogoeva-Kostovska Citation: El-Ghandour N, Sawan M, Goel A, Abdelkhalek AA, Abdelmotleb AM, Ali T, Aziz MSA, Soliman MAR. A Prospective Randomized Study of the Safety and Efficacy of Transforaminal Lumbar Interbody Fusion Versus Posterior Lumbar Interbody Fusion in the Treatment of Lumbar Spondylolisthesis: A Cost utility from a Lower-middle-income Country Perspective and Review of Literature. Open Access Maced J Med Sci. 2021 Aug 03; 9(B):636-645. https://doi.org/10.3889/oamjms.2021. 6569
Learning Management System Usage among Undergraduates in a Developing Context: An Extension to the Technology Acceptance Model

Why are students in developing countries reluctant to effectively and efficiently participate in Learning Management Systems (LMSs)? Many researchers have conducted focusing on validating existing theories in developing contexts. This article aims to extend the knowledge about the Technology Acceptance Model (TAM) by incorporating external variables - subjective norms, experience in the internet and computer, self-efficacy, technical support, and anxiety - which will lead to an efficient and effective LMS usage in developing contexts.