Miracle-dz/UniFAR-FTUs huggingface dataset:
Work-life balance as predictors of job satisfaction in the tertiary educational sector

Abstract This paper examines work-life balance as a predictor of job satisfaction in the tertiary education sector. The structural equation model was used to quantitatively analyse cross-sectional data gathered from 476 employees of 8 tertiary institutions operating in the Greater Accra region of Ghana. The study concludes that workplace support has a positive effect on personal life interference with work, and work interference with personal life. Work interference with personal life and personal life interference with work had a negative relationship with satisfaction with work life. The study recommends that personal life interference with work and work interference with the personal life of workers should be a priority of tertiary institutions, as it will help improve workplace support.
Large Free Algebras in the Ring of Fractions of Skew Polynomial Rings

It is shown that the division ring of quotients of a skew polynomial ring of automorphism type, if infinite‐dimensional over its centre k and satisfying suitable hypotheses, contains the group algebra of a free group of large rank (usually at least ∣k∣). The result applies, in particular, to the skew polynomial rings constructed from rational function fields, and affirmatively settles the conjectures of Makar–Limanov and Lichtman in this case.
Observed Ocean Conditions and Hurricane Hilda, 1964

Abstract Hurricane Hilda crossed the Gulf of Mexico in the period 30 September to 4 October 1964, developing into a very severe hurricane in the central Gulf. Sea temperature data available prior to the storm indicated what was probably a typical late summer situation with some surface temperatures running above 30C. Beginning 5 October 1964, a 7-day cruise was conducted over the area where hurricane winds had been observed. Using the GUS III of the Galveston Biological Laboratory of the Bureau of Commercial Fisheries, four crossings of the hurricane path were made. Bathythermograph observations were taken regularly to 270 m and hydrographic casts to 125 m. The data on all four crossings indicated similar patterns. The observed temperature-depth structures after the storm indicated that the warm ocean surface layers were transported outward from the hurricane center, cooling and mixing as they moved; that these waters converged outside of the central storm area with the result that downwelling to some 80 .
Domain-like Incommensurate Charge-Density-Wave States and the First-Order Incommensurate-Commensurate Transitions in Layered Tantalum Dichalcogenides. I. 1T-Polytype

The incommensurate (I) states of the triple charge density waves (CDW) in 1T-TaS 2 are studied in details by taking into account a sufficiently large number of harmonics. A domain-like structure of the I-CDW state is shown to be realized as the fundamental wave vector of the I state approaches to the commensurate (“3×1” superstructure) wave vector; the domain boundary is characterized generally by a change of the phase and amplitude of the CDW, and inside the domain an approximately commensurate CDW is stabilized. The nature of the commensurability energy and the coexistence of three CDW's are reflected in the pattern of the domain-like structure. The successive first-order transitions in 1T-TaS 2 are discussed in this connection. The presence of a domain-like structure, which our theory predicts for the nearly commensurate phase of 1T-TaS 2 , is consistent with the recent X-ray photoemission experiment by Hughes and Pollak.
Frequency-velocity-scalar filtered mass density function for large eddy simulation of turbulent flows

A methodology termed “frequency-velocity-scalar filtered mass density function” (FVS-FMDF) is developed for large eddy simulation (LES) of turbulent flows. The FVS-FMDF takes account of unresolved subgrid scales (SGSs) by considering the joint probability density function (PDF) of the frequency, the velocity, and the scalar fields. An exact transport equation is derived for the FVS-FMDF in which the effects of convection and chemical reaction are in closed forms. The unclosed terms in this equation are modeled in a fashion similar to PDF methods in Reynolds-averaged Navier–Stokes simulations. The FVS-FMDF transport is modeled via a set of stochastic differential equations (SDEs). The numerical solution procedure is based on a hybrid finite-difference (FD)/Monte Carlo (MC) method in which the LES filtered transport equations are solved by the FD, and the set of SDEs is solved by a Lagrangian MC procedure. LES of a temporally developing mixing layer is conducted via the FVS-FMDF, and the results are compare.
The Association between Self-Rated Health Status, Psychosocial Stress, Eating Behaviors, and Food Intake According to the Level of Sunlight Exposure in Korean Adults

Sunlight exposure has been reported to have various beneficial effects on human health. This study investigated the relationship between self-rated health status, psychosocial stress, eating behaviors, and food intake according to sunlight exposure in 948 adults. Sunlight exposure was classified as less than one hour, less than three hours, and greater than three hours. Of the participants, 49.2% had fewer than three hours of daily exposure to sunlight. Regarding participants exposed to sunlight for less than one hour, the largest response was that they did not engage in outdoor activities on weekdays or weekends, and the rate of being outdoors in the shade on sunny days was the highest in this group at 42.7%. Furthermore, the participants exposed to sunlight for less than one hour had a lower health response than the other two groups, and there were significantly more participants classified in the stress risk group. Regarding eating habits, those with less than an hour of exposure to sunlight frequently ate fried foods, fatty foods, added salt, and snacks, and had significantly lower total dietary scores or three regular meals. Additionally, their frequency of consumption of cereals, milk and dairy products, orange juice, and pork was also significantly lower than the other groups. Thus, it is necessary to provide sufficient guidelines for adequate sunlight exposure and food intake because participants with low sunlight exposure may have low vitamin D synthesis and insufficient food intake.
Comprehensive Discovery of the Accessible Primary Amino Group-Containing Segments from Cell Surface Proteins by Fine-Tuning a High-Throughput Biotinylation Method

Cell surface proteins, including transmembrane and other surface-anchored proteins, play a key role in several critical cellular processes and have a strong diagnostic value. The development of quick and robust experimental methods remains vital for the accurate and comprehensive characterization of the cell surface subproteome of individual cells. Here we present a high-throughput technique which relies on the biotinylation of the accessible primary amino groups in the extracellular segments of the proteins, using HL60 as a model cell line. Several steps of the method have been thoroughly optimized to capture labeled surface proteins selectively and in larger quantities. These include the following: improving the efficiency of the cell surface biotinylation; reducing the endogen protease activity; applying an optimal amount of affinity column and elution steps for labeled peptide enrichment; and examining the effect of various solid-phase extraction methods, different HPLC gradients, and various tandem mass spectrometry settings. Using the optimized workflow, we identified at least 1700 surface-associated individual labeled peptides (~6000–7000 redundant peptides) from the model cell surface in a single nanoHPLC-MS/MS run. The presented method can provide a comprehensive and specific list of the cell surface available protein segments that could be potential targets in various bioinformatics and molecular biology research.
Socio-Cultural Dynamics of Women Participation in Socio-Economic Development: Experiences of Women in The Bongo Traditional Area of the Upper East Region

Empowering women to contribute their quota to community and national development has become a contemporary issue embraced worldwide. Despite the fact that women’s political participation right has been enshrined in international law, little is known about the struggles and experiences women in Africa face in their quest to participate in the development of their respective communities and the country at large. This study examined the socio-cultural factors affecting the participation of women in socio-economic development in Bongo Traditional Area of the Upper East Region of Ghana. The study adopted the descriptive survey research design. Questionnaires were adopted in soliciting responses from 123 respondents. Qualitative data was also obtained by conducting unstructured interviews with the District Chief Executive of the Bongo District, a former Assembly Woman, a Community Based Organization Manager, a reformed Deviant, and the Tindana. Three focus group discussions (FGDs) were also held with men and women groups with the aid of FGD guide The study revealed that the patrilineal system, extended family system, early marriage, early parenting, land ownership, ownership of valuable properties, seeking of permission from husbands before accessing credit and kind of animals to rear negatively affects the participation of women in the development of the Bongo traditional area. The study thus recommended that, the National Commission for Civic Education, media, district assembly and traditional authority should collaborate in educating and sensitizing people as well as adopt custodian reforms of cultural values that have negative influence on women while emphasizing the important role women play in socio-economic development.
Study of the out-of-plane vibrational modes in thin-film amorphous silicon micromechanical disk resonators

Thin-film silicon micro resonators are fabricated by surface micromachining at temperatures that are CMOS and large area substrate-compatible. Disk resonators offer large working surfaces and a large number of vibrational modes. The vibrational modes of micromechanical disk resonators made from hydrogenated amorphous silicon thin films were studied in this work. The dynamic behavior of these structures is shown to be mechanically described to be in the transition between a membrane and a plate due to the influence of residual stresses generated during the film growth and to thermal mismatch with underlying layers. Non-degenerate modes are observed as a consequence of the radial symmetry and their effective stiffness is related to the anchor geometry and the parity of the number of diametric nodal lines. The experimentally measured frequencies were compared with the simulated values from finite element modeling with good agreement. Investigation of the intrinsic quality factors shows that there is a depend.
A Skeletal Muscle-Centric View on Time-Restricted Feeding and Obesity under Various Metabolic Challenges in Humans and Animals

Nearly 50% of adults will suffer from obesity in the U.S. by 2030. High obesity rates can lead to high economic and healthcare burdens in addition to elevated mortality rates and reduced health span in patients. Emerging data demonstrate that obesity is a multifactorial complex disease with various etiologies including aging, a lifestyle of chronic high-fat diets (HFD), genetic predispositions, and circadian disruption. Time-restricted feeding/eating (TRF; TRE in humans) is an intervention demonstrated by studies to show promise as an effective alternative therapy for ameliorating the effects of obesity and metabolic disease. New studies have recently suggested that TRF/TRE modulates the skeletal muscle which plays a crucial role in metabolism historically observed to be impaired under obesity. Here we discuss recent findings regarding potential mechanisms underlying TRF’s modulation of skeletal muscle function, metabolism, and structure which may shed light on future research related to TRF as a solution to obesity.
Extracellular matrix physical properties govern the diffusion of nanoparticles in tumor microenvironment

Significance Nanoparticles (NPs) have shown great potential for cancer diagnosis and treatment. However, poor delivery efficiency of NPs has been proved in the tumor extracellular matrix (ECM) in vivo. Though various methods (e.g., modulation of NP size, shape, surface charge, rigidity, or tumor microenvironment) have been developed to enhance NP diffusion, the efficiency is still unsatisfying and the underlying mechanism of the influence of tumor ECM physical properties on NPs diffusion remains unexplored. In this work, we performed molecular dynamics (MD) simulations and in vitro experiments to explore the diffusion mechanism of NPs in tumor ECM with different density, stiffness, and structure. And, we proposed an estimation matrix to predict NP diffusion efficiency according to clinical tumor physical properties.
Potential of halotolerant PGPRs in growth and yield augmentation of Triticum aestivum var. HD2687 and Zea mays var. PSCL4642 cultivars under saline conditions

This study aimed to culture and screen salt-tolerant Plant growth promoting rhizobacteria (PGPRs) from Bougainvillea glabra rhizosphere to improve wheat HD-2687 and maize PSCL-4642 cultivars under saline conditions up to the seedling stage. Twenty-four rhizobacterial isolates were screened for salt tolerance at different NaCl levels. Indole acetic acid (IAA) production, phosphate solubilization, and siderophore and hydrogen cyanide (HCN) production of salinity-tolerant isolates were tested. Positive salt-tolerant PGPRs were further subjected to seedling studies to examine the improvement in the development of experimental crops under 50, 100, 150, and 200 mM NaCl concentrations with/without bacterial inoculant. Of the 24 isolates, BoGl123 was the most promising PGPR, which showed the maximum phosphate solubilization, and IAA, siderophore and HCN production. It was further subjected to seedling studies. In comparison with controls, BoGl123 resulted in a higher radicle length in maize (34 mm, 87.4%) and wheat (26.8 mm, 85.8%) at the 50 mM salinity level. At the 100 mM NaCl level, the radicle length of wheat and maize seedlings was increased by 82.5% and 78.6%, respectively, compared with controls. At different NaCl concentrations, BoGl123 improved the plumule length of seedlings in both crops. The stress tolerance attributes and plant growth promotion (PGP) indicate the potential of Pseudomonas fluorescens BoGl123 to be used as a microbial inoculant in the cultivation of wheat and maize under stressful conditions.
Energy levels, radiative rates and electron impact excitation rates for transitions in He-like N VI, F VIII and Na X

In this paper, we report calculations for energy levels, radiative rates and electron impact excitation rates for transitions in He-like N VI, F VIII and Na X. The general-purpose relativistic atomic structure package (grasp) is adopted for calculating energy levels and radiative rates, and for determining the collision strengths and subsequently the excitation rates, the Dirac atomic R-matrix code (darc) and the flexible atomic code (fac) are used. Oscillator strengths, radiative rates and line strengths are reported for all E1, E2, M1 and M2 transitions among the lowest 49 levels of N VI, F VIII and Na X. Collision strengths have been averaged over a Maxwellian velocity distribution and the effective collision strengths so obtained are reported over a wide temperature range below 107 K. Additionally, lifetimes are also reported for all calculated levels of the above three ions.
In Silico Prediction of Human Clinical Pharmacokinetics with ANDROMEDA by Prosilico: Predictions for an Established Benchmarking Data Set, a Modern Small Drug Data Set, and a Comparison with Laboratory Methods

There is an ongoing aim to replace animal and in vitro laboratory models with in silico methods. Such replacement requires the successful validation and comparably good performance of the alternative methods. We have developed an in silico prediction system for human clinical pharmacokinetics, based on machine learning, conformal prediction and a new physiologically-based pharmacokinetic model, i.e. ANDROMEDA. The objectives of this study were: a) to evaluate how well ANDROMEDA predicts the human clinical pharmacokinetics of a previously proposed benchmarking data set comprising 24 physicochemically diverse drugs and 28 small drug molecules new to the market in 2021; b) to compare its predictive performance with that of laboratory methods; and c) to investigate and describe the pharmacokinetic characteristics of the modern drugs. Median and maximum prediction errors for the selected major parameters were ca 1.2 to 2.5-fold and 16-fold for both data sets, respectively. Prediction accuracy was on par with, or better than, the best laboratory-based prediction methods (superior performance for a vast majority of the comparisons), and the prediction range was considerably broader. The modern drugs have higher average molecular weight than those in the benchmarking set from 15 years earlier (ca 200 g/mol higher), and were predicted to (generally) have relatively complex pharmacokinetics, including permeability and dissolution limitations and significant renal, biliary and/or gut-wall elimination. In conclusion, the results were overall better than those obtained with laboratory methods, and thus serve to further validate the ANDROMEDA in silico system for the prediction of human clinical pharmacokinetics of modern and physicochemically diverse drugs.
Interplay between Networking Capability and Hospital Performance in Indonesia’s Medical Tourism Sector

Medical tourism is an industry that is currently developing, but research that focuses on the analysis of supply and institutions as a unit in Indonesia is sparse. This research aims to investigate the variables of digital transformation and resource integration that influence hospital performance, considering the expansion of hospitals’ capacities for networking in medical tourism. A structural equation model is used to evaluate the hypothesis. According to our findings, digital transformation and resource integration both have a beneficial effect on networking capabilities. On the other hand, the implementation of digital transformation does not improve hospital performance. Digital transformation has a good link with hospital performance but has no statistically significant effect on hospital performance. In the meantime, the capabilities of resource integration and networking have a positive effect on the overall operation of hospitals. In a similar vein, the ecosystem of medical tourism helps to improve the connection between a hospital’s networking capabilities and its overall performance. It is anticipated that the findings of this study will serve as a reference for those in the policymaking and healthcare industries to develop medical tourism.
Effect of Thiosulfate Concentration and Leaching Temperature in Ammoniacal Thiosulfate Leaching of Refractory Sulfide Gold Ore

Tiosulfat sebagai larutan pelindian emas pertama kali dipelajari pada tahun 1979 untuk menemukan alternatif larutan sianida dan merkuri yang banyak digunakan dalam industri ekstraksi emas meskipun berdampak negatif bagi lingkungan. Sampel bijih yang digunakan adalah bijih asli dari Bolaang Mongondow, Sulawesi Utara. Berdasarkan pengamatan Mikroskop Optik dan karakterisasi LIBS, terdapat senyawa pirit yang merupakan salah satu karakteristik bijih sulfida. Menurut fluoresensi sinar-X dan Inductively Coupled Plasma, bijih mengandung sekitar 14,62% ? Fe, 6,69% ? S, 0,15% Cu, dan 0,27 ppm Au. Penelitian ini bertujuan untuk mengetahui pengaruh konsentrasi tiosulfat dan temperatur pelindian pada pelindian tiosulfat amoniak bijih emas sulfida refraktori terhadap kelarutan emas. Penelitian ini dilakukan dengan metode leaching skala laboratorium. Hasil leaching kemudian diperiksa dengan Inductively Coupled Plasma (ICP). Konsentrasi tiosulfat (0,05M, 0,1M, dan 0,2M) dan pengaruh temperatur (25? C, 40? C, 60? C) dipelajari. Ekstraksi emas maksimum (62%) diperoleh dengan menggunakan konsentrasi tiosulfat 0,1M pada 40? C selama 2 jam dengan kepadatan pulp 20%. Kecepatan pengadukan dan pH larutan berair masing-masing adalah 400 rpm dan 10. Berdasarkan hasil tersebut dapat disimpulkan bahwa konsentrasi larutan tiosulfat dan temperatur pelindian akan mempengaruhi kelarutan emas. Thiosulfate as gold leach solution first studied in 1979 to found alternative of cyanide and mercury solution which are widely used in gold extraction industry although it’s negative impact for the environment. The ore sample is native ore from Bolaang Mongondow, North Sulawesi. According to Optical Microscope observation and LIBS characterization, there are pyrite compound which is one of the chacaracteristic of sulfide ore. According to X-ray fluorescence and Inductively Coupled Plasma, the ore contained about 14.62% Fe, 6.69% S, 0.15% Cu, and 0.27 ppm Au. This study aimed to determine the effect of thiosulfate concentration and leaching temperature in ammoniacal thiosulfate leaching of refractory gold sulfide ores on the solubility of gold. This research was conducted by laboratory scale of leaching method. The leaching result is then checked by Inductively Coupled Plasma (ICP). The concentration of thiosulfate (0.05M, 0.1M, and 0.2M) and the effect of temperature (250 C, 400 C, 600 C) were studied. Maximum gold extraction (62%) was obtained using 0.1M of thiosulfate concentrations at 400 C for 2 h with 20% of pulp density. Stirring speed and the pH of the aqueous solution were 400 rpm and 10, respectively. According to the results, it can be concluded that the concentration of Thiosulfate solution and leaching temperature will affect the dissolution of gold.
Safety and efficacy of prophylactic anticoagulation versus therapeutic anticoagulation in hospital‐admitted COVID‐19 patients: A systematic review and meta‐analysis of randomized controlled trials

COVID‐19 disease‐related coagulopathy and thromboembolic complication, an important aspect of the disease pathophysiology, are frequent and associated with poor outcomes, particularly significant in hospitalized patients. Undoubtedly, anticoagulation forms a cornerstone for the management of hospitalized COVID‐19 patients, but the appropriate dosing has been inconclusive and a subject of research. We aim to review existing literature and compare safety and efficacy outcomes of prophylactic and therapeutic dose anticoagulation in such patients.
Myasthenia Gravis Induced by Immune Checkpoint Inhibitors: An Emerging Neurotoxicity in Neuro-Oncology Practice: Case Series

Immunotherapy with immune checkpoint inhibitors (ICIs) have been reported to induce de novo or exacerbate pre-existing Myasthenia Gravis (MG). We present a single center case series of patients who developed an immune-related myasthenia gravis (irMG) related with ICIs. We performed a retrospective chart review of the electronic medical records between 1 September 2017 and 2022. We report the clinical features, presentation forms, diagnostic workflows, general management and outcomes of six patients who received ICIs for different solid organ malignancies and developed an irMG frequently overlapping with immune-related myocarditis and/or myositis. The aim of the article is to describe the clinical features, treatment and outcomes of this challenging and potentially life-threating syndrome, comparing our data with those described in the literature. Differences between irMG and classic MG are highlighted.