Miracle-dz/UniFAR-FTUs huggingface dataset:
An Intentional Wholeness Focus and the Association With Burnout in Graduate Students

Abstract Rates of stress, anxiety, depression, and burnout for university students are concerning. As in other competitive professional fields, graduate students in occupational therapy, physical therapy, and speech language pathology face many performance pressures. Creating supportive learning and wholeness climates along with individual grit, resilience, and healthy spirituality have the potential to positively impact these pressures. The study’s purpose was to examine factors related to burnout within an institution committed to creating supportive learning and wholeness environments. Three hundred and fifty-three graduate students from occupational therapy, physical therapy, and speech language pathology graduate programs were recruited to participate in a cross-sectional survey exploring student functioning using primarily validated measures. Hierarchical multiple regressions were utilized to test the unique contributions of perceived learning and wholeness climates, demographics, mental health factors, and potential coping factors to better understand burnout/disengagement and burnout/exhaustion. All models accounted for a significant amount of the variance in both burnout/disengagement (38.2%) and burnout/exhaustion (46.9%). Higher student perceptions of positive wholeness and learning climates, grit, and personal spirituality/peace suggested lower burnout/disengagement, but spirituality/meaning had an unexpected negative outcome. Burnout/exhaustion was negatively associated with anxiety, depression, and spirituality/faith while positively with spirituality/peace. Overall, students’ views of the university providing a supportive wholeness and learning climate as well as their personal grit was associated with lower burnout. Depression and anxiety were negatively associated with burnout/exhaustion. Spirituality was more complicated with variation in risk versus supportive factors. Results may help guide future studies, provide suggestions for specific programming, and promote supportive university environments.
The Atherosclerosis Risk in Communities Study

Weight gain increases the prevalence of obesity, a risk factor for cardiovascular disease. Nevertheless, unintentional weight loss can be a harbinger of health problems. The Atherosclerosis Risk in Communities Study (1987– 2009) included 15,792 US adults aged 45–64 years at baseline and was used to compare associations of long-term (30 years) and short-term (3 years) weight change with the risks of coronary heart disease (CHD) and ischemic stroke. Age-, gender-, and race-standardized incidence rates were 4.9 (95% confidence interval (CI): 4.6, 5.2) per 1,000 person-years for CHD and 2.5 (95% CI: 2.3, 2.8) per 1,000 person-years for stroke. After controlling for baseline body mass index and other covariates, long-term weight gain (since age 25 years) of more than 2.7% was associated with elevated CHD risk, and any long-term weight gain was associated with increased stroke risk. Among middle-aged adults, short-term (3-year) weight loss of more than 3% was associated with elevated immediate CHD risk (hazard ratio=1.46, 95% CI: 1.18, 1.81) and stroke risk (hazard ratio=1.45, 95% CI: 1.10, 1.92). Risk tended to be larger in adults whose weight loss did not occur through dieting. Avoidance of weight gain between early and middle adulthood can reduce risks of CHD and stroke, but short-term, unintentional weight loss in middle adulthood may be an indicator of immediate elevated risk that has not previously been well recognized. body mass index; body weight changes; coronary heart disease; ischemic stroke
Acoustic Volume Scattering at the Bermuda Ocean Acre Site (Cruise 14 and Related Earlier Studies).

Abstract : Volume scattering strengths at selected frequencies from 3.85 to 15.50 kHz, determined from Ocean Acre measurements in June 1972, are described in terms of diurnal variations, daily variability, frequency characteristics, and seasonal trends. Day-night comparisons of profiles at 13.50 and 15.50 kHz showed a maximum increase in scattering strength of 35 dB in the depth range from 120 to 330 m and of 15 dB above 120 m. Integrated scattering strengths varied with depth by as much as 15 dB, whereas total-column strengths at night were only 3 to 4 dB above daytime levels. Because of this small difference, the latter result is considered inadequate in describing the large diurnal variations associated with the vertical migration of scatterers. Unlike earlier results, night-to-night variability of scattering strength during the stable period was as large as 10 dB for all of the frequencies over most of the water columns. At all of the frequencies, nighttime scattering strengths peaked within 120 m of the surface. At 13.50 and 15.50 kHz, additional contributions occurred in the depth interval from 250 to 550 m. The spectra of total-column strengths exhibited a broad resonance centered about 9.00 kHz which was unlike the low- and high-frequency resonances found in earlier studies. Scattering strength at 3.85 kHz experienced an increase from spring to summer, although the amounts were not the same in two different years.
Medicine Open Access

The field of performing transcatheter interventions to treat vascular lesions has exploded over the past 20 years. Not only has the technology changed, especially in the arena of balloon/stent devices, but the techniques of approaching complex lesions has evolved over the past decade. Lesions that no one would have imagined treating back in the 1990's are now being done routinely in the catheterization suite. This book provides an update on the current techniques and devices used to treat a wide variety of lesions. Though, at first, the outward appearance of the topics appears to be varied, they are all related by the common thread of treating vascular lesions. We hope, by publishing this book, to accomplish two things: First, to offer insight from experts in their field to treat, both medically and procedurally, complex vascular lesions that we frequently encounter. Secondly, we hope to promote increased communication between areas of medicine that frequently don't communicate, between adult interventional cardiologists, pediatric interventional cardiologists, interventional radiologists, and neurosurgeons. Much can be learned from our respective colleagues in these areas which can further our own world of interventions.
Replication of Marek’s Disease Virus is dependent on synthesis of de novo Fatty 1 Acid and Prostaglandin E2 2

Marek’s disease virus (MDV) causes deadly lymphoma and induces an imbalance of the 27 lipid metabolism in infected chickens. Here, we discovered that MDV activates fatty acid 28 synthesis (FAS) pathway in primary chicken embryo fibroblasts (CEF). In addition, MDV 29 infected cells contained high levels of fatty acids and showed an increased numbers of 30 lipid droplets (LDs). Chemical inhibitors of the FAS pathway (TOFA and C75) reduced 31 MDV titre by approximately 30 folds. Addition of the downstream metabolites including 32 malonyl-CoA or palmitic acid completely restored the inhibitory effects of the FAS 33 inhibitors. Furthermore, we could demonstrate that MDV infection activates COX-2/PGE 2 34 pathway as evident by increased levels of arachidonic acid, COX-2 expression and PGE 2 35 synthesis. Inhibition of COX-2/PGE 2 pathway by chemical inhibitors or knockdown of 36 COX2 using shRNA reduced MDV titres, suggesting that COX-2 promotes virus 37 replication. Exogenous PGE 2 completely restored the inhibition of the COX-2/PGE 2 38 pathway in MDV replication. Unexpectedly, exogenous PGE 2 also partially rescued the 39 inhibitory effects of FAS inhibitors on MDV replication, suggesting that there is link 40 between these two pathways in MDV infection. Taken together, our data demonstrate that 41 the FAS and COX-2/PGE 2 pathways play an important role in the replication of this deadly 42 pathogen. 2/PGE 2 pathway which supports MDV replication by activating PGE 2 /EP2 and PGE 2 /EP4 52 signalling pathways. FASN MDV lipid
Evaluation of antioxidant and free radical scavenging activities of honeybush tea (Cyclopia)

/n vitro model systems, including the 1,1-diphenyl-2-picrylhydrazyl (DPPH·) and superoxide anion (02.') radical scavenging methods and inhibition of linoleic acid peroxidation, were used to assess the antioxidant and antiradical potential of honeybush aqueous extracts and crude phenolic fractions and compounds. For the purpose of evaluating test materials of this divergent nature in the same assay, comparison of antiradical efficiencies was executed on a mass basis. In addition, the comparison of the antiradical efficiencies of the phenolic compounds was performed on a molar basis to elucidate structure-activity relationships. Comparison of aqueous extracts prepared from unfermented and fermented material of Cyclopia intermedia, C. genistaides, C. macu/ata, C. sessi/if/ora and C. subtemata showed that the extract of unfermented C. sessi/if/ora (highest total polyphenol content) was the most effective scavenger of both DPPH· and O2. ' (P s 0.05). Fermented C. subtemata, followed by fermented C. macu/ata and C. intermedia, showed the weakest hydrogen-donating (H-donating) ability towards DPPH·, whilst the latter two species showed the weakest scavenging of O2. ' (P s 0.05). This phenomenon is partially attributed to the soluble solids offermented C. subtemata, which did not differ significantly from fermented C. macu/ata and C. intermedia, containing the lowest total polyphenol contents (P :=; 0.05). Aqueous extracts from fermented and unfermented C. genistoides showed the most effective inhibition of linoleic acid peroxidation, with unfermented C. intermedia showing the weakest activity. Fermentation lowered the antiradical efficiency of aqueous extracts from the different species and crude phenolic fractions from C. intermedia towards DPPH· and O2. ', possibly due to the oxidation of the phenolic compounds. However, inhibition of linoleic acid peroxidation by aqueous extracts and phenolic fractions were not affected by fermentation (P ~ 0.05), except forthe aqueous extract of unfermented C. intermedia being slightly less effective than its fermented equivalent (P :=; 0.05). A strong relationship was observed between the structures of honeybush tea phenolic compounds and their relative antiradical efficiencies. With comparison on a molar basis, the reference compound, quercetin, as well as the honeybush polyphenols, luteolin, mangiferin and isomangiferin, were the most effective scavengers of DPPH·, Stellenbosch University http://scholar.sun.ac.za
The Consequences of Radical Reform: The French Revolution

The French Revolution of 1789 had a momentous impact on neighboring countries. The French Revolutionary armies during the 1790s and later under Napoleon invaded and controlled large parts of Europe. Together with invasion came various radical institutional changes. French invasion removed the legal and economic barriers that had protected the nobility, clergy, guilds, and urban oligarchies and established the principle of equality before the law. The evidence suggests that areas that were occupied by the French and that underwent radical institutional reform experienced more rapid urbanization and economic growth, especially after 1850. There is no evidence of a negative effect of French invasion. Our interpretation is that the Revolution destroyed (the institutional underpinnings of) the power of oligarchies and elites opposed to economic change; combined with the arrival of new economic and industrial opportunities in the second half of the 19th century, this helped pave the way for future economic growth. The evidence does not provide any support for several other views, most notably, that evolved institutions are inherently superior to those 'designed'; that institutions must be 'appropriate' and cannot be 'transplanted'; and that the civil code and other French institutions have adverse economic effects.
Plant Seedlings Classification Using Deep Learning

: Agriculture is very important to human continued existence and remains a key driver of many economies worldwide, especially in underdeveloped and developing economies. There is an increasing demand for food and cash crops, due to the increasing in world population and the challenges enforced by climate modifications, there is an urgent need to increase plant production while reducing costs. Preceding instrument vision methods established for selective weeding have confronted with major challenges for trustworthy and precise weed recognition. In this paper, plant seedlings classification approach is presented with a dataset that contains approximately 5,000 images with 960 unique plants that belong to 12 species at a few developing phases. Convolutional Neural Network (CNN) algorithms, a deep learning technique extensively applied to image recognition was used, for this task. The results found that CNN-driven seedling classification applications when used in farming automation have the latent to enhance crop harvest and improve output and productivity when designed properly. The trained model achieved an accuracy of 99.48% on a held-out test set, demonstrating the feasibility of this approach.
Ephemeropteran and plecopteran communities in glacial rivers

From a study of glacier-fed catchments along a European latitudinal and climatic gradient, the relationships between the distribution of mayfly (Ephemeroptera) and stonefly (Plecoptera) nymphs and environmental variables were explored. Canonical Correspondence Analysis (CCA) and Generalised Additive Models (GAMs) demonstrated clear responses of mayfly and stonefly generic composition and taxa richness to environmental gradients, notably maximum water temperature and channel stability as these change downstream of glacial sources. GAMs developed for aquatic insects are well suited to detect environmental impacts, including climate change.
A path-following inexact Newton method for optimal control in BV

We study a PDE-constrained optimal control problem that involves functions of bounded variation as controls and includes the TV seminorm of the control in the objective. We apply a path-following inexact Newton method to the problems that arise from smoothing the TV seminorm and adding an $H^1$ regularization. We prove in an infinite-dimensional setting that, first, the solutions of these auxiliary problems converge to the solution of the original problem and, second, that an inexact Newton method enjoys fast local convergence when applied to a reformulation of the optimality system in which the control appears as implicit function of the adjoint state. We show convergence of a Finite Element approximation, provide a globalized preconditioned inexact Newton method as solver for the discretized auxiliary problems, and embed it into an inexact path-following scheme. We construct a two-dimensional test problem with fully explicit solution and present numerical results to illustrate the accuracy and robustness of the approach.
Drift and Volatilization of Some Pesticides Sprayed on Chinese Cabbages

In order to investigate the drift of pesticides sprayed on Chinese cabbage, 7 pesticides chlorpyrifos, EPN, pirimiphos-methyl, phenthoate, tetradifon, dicofol and bifenthrin were applied in two sets of field tests. The pesticide residues were quantified bar multiple-residue analysis, in which the recovery rate was 7892% and standard deviation was . It was found that most of the tested pesticides were spread by drift to neighbouring area and brought about the contamination of the unsprayed crops. The extent of drift varied depending upon the pesticide, distance and wind direction. The mean residue levels on unsprayed crops were 0.66% at 3 meter distance, 0.10% at 6 m distance and 0.05% at 9 m distance from the applied area and the maximum level was 1.83% of the residue on sprayed crops.
Interactions between Stress and Vestibular Compensation – A Review

Elevated levels of stress and anxiety often accompany vestibular dysfunction, while conversely complaints of dizziness and loss of balance are common in patients with panic and other anxiety disorders. The interactions between stress and vestibular function have been investigated both in animal models and in clinical studies. Evidence from animal studies indicates that vestibular symptoms are effective in activating the stress axis, and that the acute stress response is important in promoting compensatory synaptic and neuronal plasticity in the vestibular system and cerebellum. The role of stress in human vestibular disorders is complex, and definitive evidence is lacking. This article reviews the evidence from animal and clinical studies with a focus on the effects of stress on the central vestibular pathways and their role in the pathogenesis and management of human vestibular disorders.
Simultaneous analysis and optimal design of truss structures via displacement method

In this paper, an efficient technique is proposed by displacement method of analysis and three metaheuristic algorithms consisting of the Colliding Bodies Optimization (CBO), Enhanced Colliding Bodies Optimization (ECBO) and Vibrating Particles System (VPS), for the simultaneous analysis and optimal design of truss structures. The presented method is applied to the minimum weight design of some planar and spatial truss structures. For examining the accuracy and efficiency of the proposed method, the problems are also designed by the same metaheuristic algorithms utilizing pure force method and pure displacement method as analysis tools (non-simultaneous) and the resulting structural weights are compared.
Modal Identification from Ambient Responses using Frequency Domain Decomposition

In this paper a new frequency domain technique is introduced for the modal identification from ambient responses, i.e. in the case where the modal parameters must be estimated without knowing the input exciting the system. By its user friendliness the technique is closely related to the classical approach where the modal parameters are estimated by simple peak picking. However, by introducing a decomposition of the spectral density function matrix, the response can be separated into a set of single degree of freedom systems, each corresponding to an individual mode. By using this decomposition technique close modes can be identified with high accuracy even in the case of strong noise contamination of the signals.
Pneumocystis jirovecii pneumonia associated with etanercept treatment in patients with rheumatoid arthritis: a retrospective review of 15 cases and analysis of risk factors

Abstract Objectives The association of anti-tumor necrosis factor therapy with opportunistic infections in rheumatoid arthritis (RA) patients has been reported. The goal of this study was to clarify the clinical characteristics and the risk factors of RA patients who developed Pneumocystis jirovecii pneumonia (PCP) during etanercept therapy. Methods We conducted a multicenter, case–control study in which 15 RA patients who developed PCP were compared with 74 RA patients who did not develop PCP during etanercept therapy. Results PCP developed within 26 weeks following the first injection of etanercept in 86.7% of the patients. All PCP patients presented with a rapid and severe clinical course and the overall mortality was 6.7%. Independent risk factors were identified using multivariate analysis and included age ≥ 65 years [hazard ratio (HR) 3.35, p = 0.037], coexisting lung disease (HR 4.48, p = 0.009), and concomitant methotrexate treatment (HR 4.68, p = 0.005). In patients having a larger number of risk factors, the cumulative probability of developing PCP was significantly higher (p < 0.001 for patients with two or more risk factors vs. those with no risk factor, and p = 0.001 for patients with one risk factor vs. those with no risk factor). Conclusion Physicians must consider the possibility of PCP developing during etanercept therapy in RA patients, particularly if one or more risk factors are present.
DETERMINANTS OF THE SUCCESSFUL USAGE OF A FIRM ’ S SNS

This research-in-progress paper aims to investigate the determinants for the successful usage of social network services (SNS) from the perspective of a firm. A new type of commercial community operated by a firm in public SNS is defined as a firm’s SNS page and the success of encouraging users’ adoption and continued usage of a firm’s SNS page is further defined as SNS success. Based on solid theoretical foundation of communicative ecology theory, a conceptual research model of SNS success is proposed. It is composed of the content quality, service quality, and social interaction quality as antecedents. Among these elements, social interaction quality is newly developed to reflect the value of interaction among community members as a second-order variable which consists of exchange information, social support, and friendship. In addition, incentives and the network size are examined as moderating variables. After building the research model and hypotheses, the measurement scales and the results of a pilot study to verify the items are described. At the end of the paper, the conclusion and the expected contribution are discussed.
Robust exponential stability analysis of neural networks with multiple time delays

This paper considers the robust stability of neural networks with multiple delays. Based on Lyapunov stability theory and linear matrix inequality technique, some new delay independent conditions are derived to guarantee the global robust exponential stability of the equilibrium point. Furthermore, the obtained results are generalized to the interval neural networks and bidirectional associative memory (BAM) neural networks. Two examples are used to show the effectiveness of the obtained results. r 2006 Elsevier B.V. All rights reserved.
The Malawi Agricultural Input Subsidy Programme: 2005-6 to 2008-9

Malawi’s implementation of a large scale agricultural input subsidy programme in 2005/6 and subsequent years has attracted significant international interest. This paper reviews the background, processes, achievements and outcomes of the programme over the period 2005/6 to 2008/9. The very large scale disbursement of heavily subsidised fertilisers and (mainly hybrid and composite maize) seed to very large numbers of beneficiaries across the country represents a significant logistical achievement and led to significant increases in national maize production and productivity, and this has contributed to increased food availability, higher real wages and wider economic growth and poverty reduction. However the latter years of the programme have also been accompanied by very high international fertilizer prices and costs and by high maize prices, the latter undermining the programme’s food security, poverty reduction and growth benefits for the majority of Malawian farmers, who are very poor and rely on purchased maize for significant amounts of their staple food requirements. Estimated economic returns to the programme have been satisfactory, given other benefits of the programme not captured in cost benefit analysis. With substantial reductions in both prices and subsidised volumes of fertilisers in subsequent years, there is considerable scope for building on achievements to substantially raise programme effectiveness, efficiency and benefits. Any application of Malawi’s subsidy experience to other countries needs to take account of special characteristics of the Malawian maize economy and of measures needed to raise such programmes’ effectiveness and efficiency and ensure their best fit with and contribution to sustainable development policies.