Miracle-dz/UniFAR-FTUs huggingface dataset:
Exploration of Switching Behavior of Sharia Banking Customer in Indonesia with Satisfaction as an Intervening Variable

The industrial revolution 4.0 will have a great impact on the level of competition in the banking industry including Islamic banking in Indonesia. The analysis of the switching behavior of sharia banking customers is very important to do because environmental change factors greatly affect customers’ behavior. This study aims to analyze the switching behavior of Islamic banking customers based on the push-pull mooring factor theory. This study is conducted on Islamic banking customers in Indonesia with the number of respondents of 100 people. This study uses a purposive sampling technique. The research instrument in the form of a questionnaire has been tested valid and reliable which is arranged based on strong indicators from the theoretical studies and previous research. Hypothesis test using path analysis proves that customers’ perception of the reward level on deposits/savings, the reputation of Islamic banks, service quality and satisfaction are the factors that influence the switching behavior of sharia banking customers. The results of this study show that customers’ perceptions of the reward level on deposits/savings and the reputation of Islamic banks are the factors that have a very positive effect on customer satisfaction of Islamic banks. Customers’ satisfaction with Islamic bank products and services can be an intervening variable to the Islamic banking customers switching behaviour.
Immunogenic and immunotolerogenic effects of extracorporeal photopheresis in high immunological risk kidney recipients. A single center case series

The immunomodulatory effects of extracorporeal photopheresis (ECP) have been used for the treatment of T‐cell mediated disorders, such as rejection in organ transplantation. Currently, it is an established therapy for heart and lung rejection, but not for kidney transplantation (KT), where experience is limited. In addition, some data suggest that ECP could generate an immune response against infections, thus being an alternative for the treatment of rejection in case of active or high‐risk of infection. In the present study, we analyze four cases of use of ECP as concomitant therapy in patients with KT and high risk of opportunistic infections due to the high burden of immunosuppression throughout their renal diseases. Two patients had concomitant viral infection (cytomegalovirus and BK virus, respectively) and three patients were on treatment for graft rejection. In the two patients with active viral infection, the infection was successfully controlled during ECP treatment. In all cases, ECP has been shown to be a safe procedure, without complications.
Notes on AISI Design Methods for Sheathing Braced Design of Wall Studs in Compression

Summary The 1962 AISI Specification provides the groundwork for rational requirements on studfastener-sheathing strength and stiffness – these requirements need to be reflected in future design methods in some form. The diaphragm based design method of Simaan and Pekoz (AISI method from 1980-2004) provides significant theoretical insights on how to incorporate torsional-flexural buckling including with one-sided and dis-similar sheathing, but the particulars of the model for the diaphragm are not physically realizable, thus modifications are a must. The limitations inherent in the current AISI-COFS Wall Stud Standard (AISI-S211-07) are noted and discussed. A preliminary list of limit states for sheathed wall studs in compression is provided.
Deep-submicrometer DC-to-RF SOI MOSFET macro-model

We present a submicrometer RF fully depleted SOI MOSFET macro-model based on a complete extrinsic small-signal equivalent circuit and an improved CAD model for the intrinsic device. The delay propagation effects in the channel are modeled by splitting the intrinsic transistor into a series of shorter transistors, for each of which a quasistatic device model can be used. Since the intrinsic device model is charge-based, our RF SOI MOSFET model can be used in both small and large-signal analyses. The model has been validated for frequencies up to 40 GHz and effective channel lengths down to 0.16 /spl mu/m.
Concentrations and emissions of airborne dust in livestock buildings in Northern Europe

Field surveys of dust concentrations within and dust emissions from cattle, pig and poultry buildings were conducted in England, the Netherlands, Denmark and Germany. Measurements of inhalable and respirable dust concentrations were made in 329 buildings. Concentrations of CO 2 within and outside the buildings were also measured to estimate ventilation rates for dust emission calculations. Dust concentrations and emissions were a⁄ected significantly by housing type and animal species. Overall mean inhalable and respirable dust concentrations were 0)38 and 0)07 mg/m3 in cattle buildings, 2)19 and 0)23 mg/m3 in pig buildings, and 3)60 and 0)45 mg/m3 in poultry buildings, respectively. Overall mean inhalable and respirable dust emission rates from the buildings were 110 and 19 mg/h bovine, 111 and 14 mg/h pig, and 12 and 2 mg/h bird, respectively. Expressed per 500 kg liveweight, the values become, respectively, 145 and 24 mg/h for cattle; 762 and 85 for pigs; and 3165 and 504 for poultry. Seasonal e⁄ects on dust concentrations in and emissions from cattle buildings were weak. Dust concentrations in pig and poultry buildings were higher in winter than summer. Inhalable dust emission rates from pig and poultry buildings were higher in summer than winter. E⁄ects of season on respirable dust emission rates from pig and poultry buildings were small. Inhalable dust concentrations in cattle buildings were higher in the day than at night, but e⁄ects di⁄ered between countries. Pig buildings showed higher dust (both inhalable and respirable) concentrations in the day than at night. Percheries and buildings for caged layers showed higher inhalable dust concentrations in the day than at night. However, dust concentrations in broiler houses were not a⁄ected by day and night. The high concentrations of inhalable dust in broiler houses, in percheries for hens and in slatted weaner and fattener houses for pigs give cause for concern for both stockman and animal health and performance. ( 1998 Silsoe Research Institute
Investigation of analog memristive switching of iron oxide nanoparticle assembly between Pt electrodes

The analog memristive switching of iron oxide (γ-Fe2O3) nanoparticle assembly was investigated. The γ-Fe2O3 nanoparticles were chemically synthesized with ∼10 nm in diameter and assembled to be a continuous layer as a switching element in Pt/nanoparticles/Pt structure. It exhibited the analog switching that the resistance decreased sequentially as repeating −V sweeps and pulses while increased as applying +V. The capacitance-voltage curves presenting hysteresis with flatband voltage shift and distortion of their shapes with respect to the applied voltage supported the redistribution of space charges in nanoparticle assembly that might induce resistive switching. The polarity-dependent analog resistance change proportional to pulse voltage, time, and number of pulses was analogy to potentiation and depression of adaptive synaptic motion.
Temperature and modulation characteristics of resonant-cavity light-emitting diodes

Resonant-cavity light-emitting diodes (RCLED) are novel, high-efficiency light-emitting diodes which employ optical microcavities. These diodes have higher intensities and higher spectral purity as compared to conventional LEDs. Analytical formulas are derived for the enhancement of the spontaneous emission along the optical axis of the cavity. The design rules for high-efficiency operation of RCLEDs are established. The temperature dependence of the emission intensity is analyzed in the range 20-80/spl deg/ and it is described by an exponential dependence with a characteristic temperature of 112 K. The modulation characteristics of RCLEDs exhibit 3 dB frequencies of 580 MHz. Eye diagrams at transmission rates of 622 Mb/s are wide open indicating the suitability of RCLEDs for high-speed data transmission.
Age-related Differences in Tumour Characteristics and Prognostic Factors for Disease Progression in Cutaneous Squamous Cell Carcinoma of the Head and Neck

Guidelines for cutaneous squamous cell carcinoma of the head and neck do not take the age of the patient into account, but instead assume equal tumour characteristics and prognostic factors for poor outcome in younger and elderly patients. The aim of this study was to compare tumour characteristics of younger (< 75 years) and elderly (≥ 75 years) patients and identify age-specific risk factors for progression of disease, comprising local recurrence, nodal metastasis and distant metastasis. Patient and tumour characteristics were compared using χ2 or Fisher’s exact tests. Multivariable competing risk analyses were performed to compare risk factors for progression of disease, incorporating the risk of dying before developing progression of disease. A total of 672 patients with primary cutaneous squamous cell carcinoma of the head and neck were retrospectively included. Larger tumour diameter, worse differentiation grade and deeper invasion were observed in older patients. In elderly patients, but not in younger patients, tumour diameter ≥ 40 mm, moderate differentiation grade and an invasion depth ≥ 2 mm were independent risk factors for progression of disease.
Absence of Cardiolipin From the Outer Leaflet of a Mitochondrial Inner Membrane Mimic Restricts Opa1-Mediated Fusion

Cardiolipin is a tetra-acylated di-phosphatidylglycerol lipid enriched in the matrix-facing (inner) leaflet of the mitochondrial inner membrane. Cardiolipin plays an important role in regulating mitochondria function and dynamics. Yet, the mechanisms connecting cardiolipin distribution and mitochondrial protein function remain indirect. In our previous work, we established an in vitro system reconstituting mitochondrial inner membrane fusion mediated by Opa1. We found that the long form of Opa1 (l-Opa1) works together with the proteolytically processed short form (s-Opa1) to mediate fast and efficient membrane fusion. Here, we extend our reconstitution system to generate supported lipid bilayers with asymmetric cardiolipin distribution. Using this system, we find the presence of cardiolipin on the inter-membrane space-facing (outer) leaflet is important for membrane tethering and fusion. We discuss how the presence of cardiolipin in this leaflet may influence protein and membrane properties, and future applications for this approach.
Explaining Spatial Disparities in Fatal Drug Overdoses, 1970-2016

: The opioid crisis has impacted many regions of the United States, transcending socioeconomic, demographic, and political divides and leading to urgent calls for public health and law enforcement inter-ventions. It has hit both micropolitan and rural smaller communities especially hard, with severe increases in prescription drug-induced fatalities over time. This paper explores socioeconomic determinants and spatial disparities of fatalities caused by drug and opioid overdose (both intentional and unintentional), focusing speciﬁcally on rural-urban diﬀerences and understanding the separate role of net farm income in the drug overdose crisis. Our panel data analysis of all US counties spanning the 1970-2016 period indicates that rurality, as measured by lower population density, is associated with higher deaths rates. Importantly, while our research suggests that the opioid crises went hand in hand with declining net farm income, the eﬀect appears to be small. Speciﬁcally, we estimate that each $ 10,000 reduction in net income per farm is associated with a 0.04 increase in overdose age-adjusted deaths per 100,000 people. This eﬀect is more prominent in counties with persistent poverty, which also is predominantly rural. Given the pronounced variability in farm ﬁnancial indicators over time, the relative health of the farm sector in rural areas may warrant more attention if the pressing health crisis is to be addressed eﬀectively.
Glycemic Control and Diabetes Related Complications in Adults with Type 1 Diabetes Mellitus and ADHD

Objective: To assess the correlation of co-morbid ADHD and diabetes-related complications in patients with type-1-diabetes-mellitus (T1DM). Methods: A retrospective cross-sectional study was conducted during 2018 using the Leumit-Health-Services(LHS) database. Diabetes-related complications were assessed in patients with T1DM and ADHD (T1DM-ADHD+) and compared with patients with T1DM alone (T1DM-ADHD−). Results: Out of 789 adult-patients with T1DM, 75 (9.5%) were T1DM-ADHD+, matched to 225 T1DM-ADHD−. HbA1C levels were higher in T1DM-ADHD+ patients (8.1% ± 1.6 vs. 7.4% ± 1.2, p < .01), as well as diabetes-related complications: neuropathy (22.7% vs. 5.8%, p < .01), ulcers (8% vs. 0.9%, p < .05), limb amputation (5.3% vs. 0.9%, p < .05), albuminuria (15.5% vs. 2.8%, p < .01), chronic renal failure (10.6% vs. 2.5%, p = .01), and emergency room admissions rate (26.7% vs. 15.1%, p < .05). In sub-analysis, lower average HbA1C levels and diabetic ulcer rates were found among ADHD patients treated with stimulants, all p < . 05. Conclusion: Co-morbidity of ADHD and T1DM is associated with poor glycemic control and higher complication rates.
Glutamine promotes antibiotic uptake to kill multidrug-resistant uropathogenic bacteria

Description Multidrug-resistant Escherichia coli metabolomes are reprogrammed by glutamine to be sensitive to ampicillin in vitro and in vivo. A metabolite to mitigate antimicrobial resistance Antibiotic resistance is a pervasive and increasing problem. Zhao et al. now show that glutamine promotes increased influx and efficacy of a variety of antibiotics against multiple species of pathogenic Gram-negative bacteria. Mechanistically, glutamine promoted changes in nucleotide metabolism that led to the up-regulation of a two-component regulatory system, resulting in increased, nonspecific membrane permeability in bacteria having varied resistance mechanisms. Glutamine supplementation was also effective in mouse models of systemic or biofilm infection, suggesting a potential strategy to enhance antibiotic efficacy. The prevalence of multidrug-resistant bacteria has been increasing rapidly worldwide, a trend that poses great risk to human and animal health and creates urgent need for pharmaceutical and nonpharmaceutical approaches to stop the spread of disease due to antimicrobial resistance. Here, we found that alanine, aspartate, and glutamate metabolism was inactivated, and glutamine was repressed in multidrug-resistant uropathogenic Escherichia coli using a comparative metabolomics approach. Exogenous glutamine promoted β-lactam–, aminoglycoside-, quinolone-, and tetracycline-induced killing of uropathogenic E. coli and potentiated ampicillin to eliminate multidrug-resistant Pseudomonas aeruginosa, Acinetobacter baumannii, Klebsiella peneumoniae, Edwardsiella tarda, Vibrio alginolyticus, and Vibrio parahaemolyticus. Glutamine-potentiated ampicillin-mediated killing was effective against biofilms of these bacteria in a mouse urinary tract infection model and against systemic infection caused by E. coli, P. aeruginosa, A. baumannii, or K. peneumoniae in a mouse model. Exogenous glutamine stimulated influx of ampicillin, leading to the accumulation of intracellular antibiotic concentrations that exceeded the amount tolerated by the multidrug-resistant bacteria. Furthermore, we demonstrated that exogenous glutamine promoted the biosynthesis of nucleosides including inosine, which in turn interacted with CpxA/CpxR and up-regulated OmpF. We validated the physiological relevance of the mechanism by showing that loss of purF, purH, cpxA, or ompF elevated antibiotic resistance in antibiotic-sensitive strains. In addition, glutamine retarded the development of ampicillin resistance. These results may facilitate future development of effective approaches for preventing or managing chronic, multidrug-resistant bacterial infections, bacterial persistence, and difficult-to-treat bacterial biofilms.
What Are the Characteristics of the Parish Nursing Research Literature and How Can it Inform Parish Nurse Practice and Research in Canada? A Scoping Review

Background Parish nursing is a specialized branch of professional nursing that promotes health and healing by integrating body, mind and spirit as a practice model. Parish nurses contribute to the Canadian nursing workforce by promoting individual and community health and acting as system navigators. Research related to parish nursing practice has not been systematically collated and evaluated. Purpose This review seeks to explore, critically appraise and synthesize the parish nurse (PN) research literature for its breadth and gaps, and to provide recommendations for PN practice and research. Methods A scoping review was conducted using Levac and colleagues’ procedures and Arksey and O’Malley's enhanced framework. The CINAHL, ProQuest and PubMed databases were comprehensively searched for original research published between 2008 and 2020. The final sample includes 43 articles. The Mixed Methods Appraisal Tool was used to critically assess literature quality. Results There is a significant gap in PN research from Canada and non-U.S. countries. Methodological quality is varied with weak overall reporting. The literature is categorized under three thematic areas: (1) practice roles of the PN, (2) role implementation, and (3) program evaluation research. Research that evaluates health promotion program interventions is prominent. Conclusions More rigorous research methods and the use of reporting checklists are needed to support evidence-informed parish nursing practice. Building relationships among parish nurses, nursing researchers and universities could advance parish nursing research and improve evidence-based parish nursing practice. Research into the cost effectiveness, healthcare outcomes, and the economic value of PN practice is needed.
Analysis insights for three FRET pairs of chemically unlinked two‐molecule FRET cytometry

Förster resonance energy transfer (FRET) is the direct energy exchange between two‐component fluorescent molecules. FRET methods utilize chemically linked molecules or unlinked fluorescent molecules such as fluoresscent protein–protein interactions. FRET is therefore a powerful indicator of molecular proximity, but standardized determination of FRET efficiency is challenged when investigating natural (chemically unlinked) interactions. In this paper, we have examined the interactions of tumor necrosis factor receptor‐1 (TNFR1) molecules expressed as recombinant C‐terminal fusion proteins of cyan, yellow, or red fluorescent protein (‐CFP, ‐YFP, or ‐RFP) to evaluate two‐molecule chemically unlinked FRET by flow cytometry. We demonstrate three independent FRET pairs of TNFR1 CFP→YFP (FRET‐1), YFP→RFP (FRET‐2) and CFP→RFP (FRET‐3), by comparing TNFR1+TNFR1 with non‐interacting TNFR1+CD27 proteins, on both LSR‐II and Fortessa X‐20 cytometers. We describe genuine FRET activities reflecting TNFR1 homotypic interactions. The FRET events can be visualized during sample acquisition via the use of “spiked” FRET donor cells, together with TNFR1+TNFR1 co‐transfected cells, as FRET channel mean fluorescence intensity (MFI) overlays. FRET events can also be indicated by comparing concatenated files of cells expressing either FRET positive events (TNFR1+TNFR1) or FRET negative events (TNFR1+CD27) to generate single‐cell scatter plots showing loss of FRET donor brightness. Robust determination of FRET efficiency is then confirmed at the single‐cell level by applying matrix calculations based on the measurements of FRET, using donor, acceptor, and FRET fluorescent intensities (I), detector channel emission coefficient (S), fluorescent protein extinction coefficients (ε) and the α factor. In this TNFR1‐based system the mean CFP→YFP FRET‐1 efficiency is 0.43 (LSR‐II) and 0.41 (Fortessa X‐20), the mean YFP→RFP FRET‐2 efficiency is 0.30 (LSR‐II) and 0.29 (Fortessa X‐20), and the mean CFP→RFP FRET‐3 efficiency is 0.56 (LSR‐II) and 0.54 (Fortessa X‐20). This study also embraces multi‐dimensional clustering using t‐SNE, Fit‐SNE, UMAP, Tri‐Map and PaCMAP to further demonstrate FRET. These approaches establish a robust system for standardized detection of chemically unlinked TNFR1 homotypic interactions with three individual FRET pairs.
Diesel fuel spray penetration, heating, evaporation and ignition: modelling vs. experimentation

The modified WAVE droplet breakup model, taking into account the transient processes during spray injection, the Effective Thermal Conductivity (ETC) liquid phase model, the gas phase model suggested by Abramzon and Sirignano, and the customised version of the Shell autoignition model have been implemented into the KIVA 2 CFD code. The observed Diesel spray tip penetration and Sauter Mean Radii show much better agreement with the prediction of the modified WAVE model compared with other droplet breakup models. The difference in the autoignition delay times predicted using the Infinite Thermal Conductivity (ITC) and ETC models is important for practical computations.
Pattern similarity in the frontoparietal control network reflects an “off-veridical” template that optimizes target-match decisions during visual search

Theories of attention hypothesize the existence of an “attentional” or “target” template that contains task-relevant information in memory when searching for an object. The target template contributes to visual search by directing visual attention towards potential targets and serving as a decisional boundary for target identification. However, debate still exists regarding how template information is stored in the human brain. Here, we conducted a pattern-based fMRI study to assess how template information is encoded to optimize target-match decisions during visual search. To ensure that match decisions reflect visual search demands, we used a visual search paradigm in which all distractors were linearly separable but highly similar to the target and were known to shift the target representation away from the distractor features (Yu & Geng, 2019). In a separate match-to-sample probe task, we measured the target representation used for match decisions across two resting state networks that have long been hypothesized to maintain and control target information: the frontoparietal control network (FPCN) and the visual network (VisN). Our results showed that lateral prefrontal cortex in FPCN maintained the context-dependent “off-veridical” template; in contrast, VisN encoded a veridical copy of the target feature during match decisions. By using behavioral drift diffusion modeling, we verified that the decision criterion during visual search and the probe task relied on a common biased target template. Taken together, our results suggest that sensory-veridical information is transformed in lateral prefrontal cortex into an adaptive code of target-relevant information that optimizes decision processes during visual search.