Miracle-dz/UniFAR-FTUs huggingface dataset:
Technology-Based Health Promotion Training Among Stroke Patients: A Randomized Controlled Trial

Stroke is a disease with a heavy social and familial care burden that can cause permanent brain damage, long-term disability, and/or death. This study aimed to determine the effect of technology-based health promotion training on the daily life activities, quality of life, and self-care of stroke patients. The study design was a Randomized Controlled Trial. The study sample included persons diagnosed with stroke diagnosed with stroke and were receiving inpatient treatment in the neurology clinic of a university hospital. The sample size was calculated as a total of 70 patients, 35 interventions and 35 controls. The intervention group patients received telephone-based education and follow-up grounded in Orem’s Self-Care Theory over a 12-week period subsequent to their discharge. The educational content was divided into three distinct categories: self-care needs with regard to health deviations, developmental self-care needs, and universal self-care practices. Data were collected using the Montreal Cognitive Assessment Scale, the Katz Index of Independence in Activities of Daily Living, Stroke-Specific Quality of Life Scale, and the Exercise of Self-Care Agency Scale. The Independent Sample T-Test was used for intergroup comparisons, and the Dependent Sample T-Test was used for intragroup pre-test and post-test comparisons. Independent variables affecting the post-test scores, such as age and gender, were analyzed using the multiple linear regression model. The scale sub-dimension variables were compared using the multivariate analysis of variance test according to the groups. When compared with the control group patients after the training, it was determined that there was a statistically significant difference in the intervention group patients’ mean scores for the Stroke-Specific Quality of Life Scale (t = 11.136, p = .001) and the Exercise of Self-Care Agency Scale (t = 14.358, p = .000). Training interventions led to enhanced awareness and knowledge about stroke among the intervention group patients. They also fostered the development of healthier lifestyle behaviors and bolstered both self-care abilities and quality of life.
Progress in the field of noninvasive diagnostics for colorectal cancer: a systematic review for the accuracy of blood-based biomarkers for detection of advanced pre-cancerous lesions

ABSTRACT Background Early detection of pre-cancerous adenomas through screening can reduce colorectal cancer (CRC) incidence. Fecal immunochemical tests are commonly used, but have limited sensitivity for pre-cancerous lesions. Blood-based screening may improve test sensitivity. This systematic review and meta-analysis was conducted to evaluate the accuracy of blood-based biomarkers for detection of advanced pre-cancerous lesions. Research design and methods We present the accuracy of blood-based biomarkers for the detection of advanced pre-cancerous lesions. EMBASE, Web of Science and PubMed databases were searched, with study populations limited to adults diagnosed with advanced pre-cancerous lesions at colonoscopy, who had a blood-based biomarker test analyzed with reports of sensitivity and specificity. Results 69 studies were identified, which assessed 133 unique biomarkers sets. The best performing test was a panel of 6 miRNAs, with a sensitivity of 95% and specificity of 90% for advanced pre-cancerous lesions. Only 6 biomarkers demonstrated sensitivity ≥ 50% and specificity ≥ 90% for the detection of advanced pre-cancerous lesions. Conclusion Many different blood-based biomarkers have been assessed for detection of advanced pre-cancerous lesions, but few have progressed beyond the discovery stage. While some biomarkers have reported high sensitivity and specificity, larger prospective studies in unbiased intended-use screening populations are required for validation.
Geochemical Assessment of Tin-Tantalum Mineralization in the Precambrian Pegmatite Exposed at Agwan Rimi, Part of Sheet 208 NE, North Central Nigeria.

Angwa Rimi area is underlain by the basement complex rocks which comprise Schist and Biotite gneiss. These host rocks are intruded by veins, which could either be pegmatite, quartz, or quartzo-feldspathic veins. Pegmatite often hosts rare metals, micas, feldspar, and quartz; particularly the quartz rich ones could also be useful as materials for construction. The pegmatite occurs as an intrusion into the schist and as ridges in the biotite gneiss where they are exposed mostly with no direct contact with the host rock. A total of six (6) whole rock samples were analyzed for major, trace and rare earth elements using inductively Coupled PlasmaAtomic Emission Spectrometry (ICP-AES) analytical technique. Petrographic analysis of both the biotite gneiss and amphibole schist reveals mineral quartz, plagioclase and biotite, in addition to the latter is the mineral amphibole and chlorite. Na/K ratio is less than (1.0) indicating poor albitization, however sample of pegmatite analyzed from the schist with the value (2.23) indicates a better albitization. Trace element analysis of Angwan Rimi pegmatites show fairly enrichment of Tantalum ranging from (13.7 to 185 ppm), rubidium (163.6 – 434.9 ppm) but low in niobium (6.6–37.3 ppm), Mean content of Ta (99.35 ppm) and Sn (105 ppm) are comparable to the rare metal pegmatites in Nigeria, although lower in Nb (21.95 ppm). Geochemical plots of Ta vs Cs, K/Rb vs Cs and K/Rb vs Rb indicate high potential for Tantalum mineralization especially those exposed at location 8.
Age Differences in Psychological Distress After Multiple Disaster Exposures: The Effect of Multidimensional Negative COVID-19 Impacts

Abstract Objective: This study examined how the multidimensional negative coronavirus disease (COVID-19) impacts contextualized the age differences in psychological distress following exposures to tornadoes and the COVID-19 pandemic. Methods: Data were from a 2-wave panel study conducted at T1 (October 2020–August 2021) and T2 (May–August 2022). Latent class analysis was conducted to explore the patterns of negative COVID-19 impacts based on a sample of 1134 at T1. Negative binomial regressions were performed to examine the age differences in psychological distress at T2, based on the working sample (N = 554), as well as the moderating effect of identified class membership, with baseline psychological distress controlled. Results: Three latent classes were identified: class 1 “low overall impacts,” class 2 “moderate overall impacts with high emotional distress,” and class 3 “severe overall impacts. ” Individuals ages 65 and over reported lower psychological distress at T2 relative to those ages 18–34 and 35–49. However, compared to people ages 18–34, 35–49, and 50–64, those ages 65 and over reported the greatest increases in T2 psychological distress if they had experienced moderate or severe overall COVID-19 impacts at T1. Conclusion: There is a pressing need for mental health interventions that are tailored to multi-disaster scenarios and age-related differences in long-term disaster recovery.
The photogeological recognition of ancient orogenic belts in Africa

Photogeological interpretation, assisted by some ground control, has been used to delineate areas of the crystalline basement in which structures formed during a particular tectonism are predominant. Such areas are referred to as 'tectonic domains'. They are recognized principally by distinctive tectonic style, by characteristic trend and axial direction, by metamorphic grade and by the sequence ot imposition of tectonisms. These criteria may be supported by geophysical data. It is unusual for all the criteria to be satisfied photogeologically, but with some ground information it is possible to draw maps which show the distribution of tectonic domains. The tectonic domain map of Karamoja, north-east Uganda, shows four domains: an early granulite facies (charnockitic) east-striking domain (A); a second, north-striking, more widely developed amphibolite facies domain (B) in which A structures are reworked and partly obliterated; a C domain which cuts across the A and B domains in a series of straight, penetrative and partially cataclastic, north-west-trending structural belts which are parallel to the Aswa Zone of central Uganda; and the Karasuk domain of recumbent flaggy folds named after the Karasuk Group. Each domain is laterally bounded, replaced or 'overprinted' by another. These relationships are illuminated by those established elsewhere in northern Uganda, and the tectonic domain map is thought to depict the interplay in north-east Uganda of the Watian, Aruan and Ghuan tectonisms which may be orogenies, and to include the Mozambiquian front impinging upon older structures. The value of the method of mapping tectonic domains lies in presenting, with a minimum of field-work, something approaching the normal tectonic map and so depicting the outlines of the ancient orogenic belts. Data such as age-determinations can be attached to the tectonic domain maps.
Anisotropic Gent–McWilliams Parameterization for Ocean Models

Abstract An anisotropic generalization of the Gent–McWilliams (GM) parameterization is presented for eddy-induced tracer transport and diffusion in ocean models, and it is implemented in an ocean general circulation model using a functional formalism to derive the spatial discretization. This complements the anisotropic viscosity parameterization recently developed by Smith and McWilliams. The anisotropic GM operator is potentially useful in both coarse- and high-resolution ocean models, and in this study the focus is on its application in high-resolution eddying solutions, for which it provides an adiabatic alternative to the more commonly used biharmonic horizontal diffusion operators. It is shown that realistically high levels of eddy energy can be simulated using harmonic anisotropic diffusion and friction operators. Isotropic forms can also be used, but these tend either to overly damp the solution when a large diffusion coefficient is used or to introduce unacceptable levels of numerical noise when .
Utilizing high resolution ribosome profiling for the global investigation of gene 1 expression in Chlamydomonas reinhardtii 2 3

3 Vincent Leon Gotsmann1, Michael Kien Yin Ting2, Nadin Haase3, Sophia Rudorf3, Reimo 4 Zoschke2, and Felix Willmund1* 5 6 7 Author’s institution(s)/affiliation(s): 8 1 Molecular Genetics of Eukaryotes, RPTU Kaiserslautern-Landau, Paul-Ehrlich-Str. 23, 9 67663 Kaiserslautern, Germany. 10 2 Max Planck Institute of Molecular Plant Physiology, Am Mühlenberg 1, 14476 Potsdam11 Golm, Germany. 12 3 Institute of Cell Biology and Biophysics, Leibniz University Hanover, Herrenhäuser-Str. 13 2, 30419 Hanover, Germany. 14 15 16 *Corresponding author: Felix Willmund (willmund@bio.uni-kl.de) 17
Regulation of chlamydial spreading from the small intestine to the large intestine by IL-22-producing CD4+ T cells

ABSTRACT Following an oral inoculation, Chlamydia muridarum descends to the mouse large intestine for long-lasting colonization. However, a mutant C. muridarum that lacks the plasmid-encoded protein pGP3 due to an engineered premature stop codon (designated as CMpGP3S) failed to do so even following an intrajejunal inoculation. This was because a CD4+ T cell-dependent immunity prevented the spread of CMpGP3S from the small intestine to the large intestine. In the current study, we found that mice deficient in IL-22 (IL-22−/−) allowed CMpGP3S to spread from the small intestine to the large intestine on day 3 after intrajejunal inoculation, indicating a critical role of IL-22 in regulating the chlamydial spread. The responsible IL-22 is produced by CD4+ T cells since IL-22−/− mice were rescued to block the CMpGP3S spread by donor CD4+ T cells from C57BL/6J mice. Consistently, CD4+ T cells lacking IL-22 failed to block the spread of CMpGP3S in Rag2−/− mice, while IL-22-competent CD4+ T cells did block. Furthermore, mice deficient in cathelicidin-related antimicrobial peptide (CRAMP) permitted the CMpGP3S spread, but donor CD4+ T cells from CRAMP−/− mice were still sufficient for preventing the CMpGP3S spread in Rag2−/− mice, indicating a critical role of CRAMP in regulating chlamydial spreading, and the responsible CRAMP is not produced by CD4+ T cells. Thus, the IL-22-producing CD4+ T cell-dependent regulation of chlamydial spreading correlated with CRAMP produced by non-CD4+ T cells. These findings provide a platform for further characterizing the subset(s) of CD4+ T cells responsible for regulating bacterial spreading in the intestine.
Evaluation of anatomical factors affecting stress urinary incontinence in female patients via dynamic pelvic floor magnetic resonance imaging.

Objective To evaluate the anatomical factors affecting stress urinary incontinence (SUI) in female patients via dynamic pelvic floor magnetic resonance imaging (DP-MRI). Methods This prospective study was conducted on 43 female patients, including 22 patients with SUI (disease group) and 21 patients without SUI (control group). All patients underwent DP-MRI. The length, volume, transverse/anteroposterior diameter, and outer/inner layer thickness of the urethra were measured on static (T2W) pulse sequences. Urethral angle, posterior urethro-vesical angle (PUVA), bladder neck-pubococcygeal angle, and position of the bladder neck and cervix relative to the pubococcygeal line were measured on dynamic (Cine) pulse sequences at rest and during evacuation phase. These parameters were compared between the groups to evaluate which anatomical factors affected SUI. The area under the ROC curve (AUC) and threshold of the sensitivity and specificity of these parameters for the diagnosis of SUI were calculated. Results The mean age of the patients was 57.3±13.8 years (disease group: 53.9±12.6 years; control group: 60.8±14.4 years). The mean number of childbirths was 2.2±0.65, and vaginal delivery accounted for 73% in each group. There was no significant difference between the two groups in terms of length, transverse diameter, outer layer thickness of the urethra, urethral angle, bladder neck-pubococcygeal angle, position of bladder neck relative to the pubococcygeal line in both resting and evacuation phases (p>0.05). There was a significant difference between the two groups regarding volume (p=0.014), anteroposterior diameter (p=0.01), inner layer thickness of the urethra (p=0.04), and PUVA (p<0.001) at rest and evacuation phases and cervix position at evacuation phase (p=0.001). The AUC of the PUVA for SUI diagnosis was 0.9 at rest and 0.98 during evacuation phases. For the threshold 133.5° at rest phase and 153.5° at evacuation phase, the sensitivity and specificity of PUVA were 0.86 and 0.86 at rest phase and 0.91 and 0.95 at evacuation phase, respectively. Conclusions PUVA was the anatomical factor that had the greatest effect on SUI and provided high sensitivity and specificity for SUI diag-nosis.
Are There Commercial Deposits of Methane Hydrates in Ocean Sediments?

Naturally occurring gas hydrates forming in the ocean floor sediments have, ever since the 1970s, been heralded as the next century's viable energy source. Is this really so? What has the Ocean Drilling Program (ODP) found out about the nature of the Bottom Simulating Reflector (BSR) as an indicator of large volumes of gas hydrates and free natural gas? The findings so far from ODP's legs 146 and 164 have been rather discouraging with respect to the in situ amounts of both gas hydrates and free gas. In the sediments drilled on Leg 146, on the Cascadia accretionary wedge off Oregon, USA, the average amount of gas hydrates above a prominent BSR was estimated at 1 – 2 percent by sediment volume. The free gas amount below the BSR was 3–4 percent by sediment volume. On Leg 164 in the Western Atlantic Ocean (Blake Plateau) some higher amounts, averaging up to 4 – 6 percent and 5 – 7 percent by volume of sediment, respectively, were found. However, on the Hydrate Ridge, off Oregon (Cascadia, just south of Leg 146), there has recently been discovered apparently large amounts of sediment-mixed gas hydrates, which may be exploitable. Although the general percentages found so far are much too low for commercial extraction (even a high-grade copper-ore on land must average more than 6 percent by volume), there may exist some high-grade regions worth exploring. But, the question remains: Where shall we seek the high-grade gas hydrate deposits in ocean sediments? Besides the obvious deep-water high porosity conventional type of reservoirs, and judging from recent findings in the Gulf of Mexico and the Caspian Sea, perhaps the most promising locations are those where mud volcanoes occur on the ocean floor.
Complications and Outcome of Cranial Cruciate Ligament Disease in Small Dogs Treated with Tiny TTA Rapid

Abstract The aim of this study was to evaluate the complications and the long-term outcome of TTA Tiny in small dogs using data from pressure-sensitive walkway analysis and the Liverpool Osteoarthritis in Dogs (LOAD) questionnaire. This is a retrospective study. Dogs under 15 kg were included. Breed, weight, gender, age, and lameness were recorded. Clinical examination, radiographs, and pressure-sensitive walkway analysis were performed during the long-term follow-up visit. Radiographs were assessed for the postoperative patellar tendon angle (PTA), bone healing, and implant position, and the postoperative complications were recorded. Twenty-nine stifles were included. One dog (3%) had an intraoperative major complication and 14 (48%) had minor complications. Medium- to long-term follow-up was available in 20 of the 23 dogs (87%). Eight (40%) dogs were followed up by telephone using the LOAD questionnaire and 12 dogs (60%) came back for a long-term follow-up appointment. The average LOAD score was 3.6 and the average lameness score was 0. All the dogs presented at a clinical follow-up were considered lame free. All the owners were pleased with the long-term result after surgery based on the LOAD score and the return to normal activity. The result from this study showed low rate of perioperative complications with the use of the TTA Tiny implant in small dogs and a good long-term outcome based on client questionnaire and the result from pressure-sensitive walkway analysis.
Natural Materials' Potential as Alternative Teeth Remineralization Agents: A Scoping Review

Abstract Dental caries is one of the world's major oral health issues. According to The Burden of Disease Study (2016), almost half of the world's population suffers oral health issues, particularly dental caries (3.58 billion individuals). Dental caries treatment through teeth remineralization can be conducted naturally or using remineralization agents. The aim of this study was to map the scientific evidence of natural materials' potential as teeth remineralization agents. The method utilized in this study was the scoping review following the guideline of Preferred Reporting Items for Systematic Reviews and Meta-Analyses Extension for Scoping Review, that is, article searching using search strategies, article screening, data extraction, and conclusion constructing. The searching process was through PubMed, EBSCOhost, and ScienceDirect using keywords and following the inclusion and exclusion criteria. Twenty articles were found and further analyzed. All articles provided the natural materials' potencies in the perspective of antibacterial, increasing saliva pH, remineralization ability, and increasing the hardness of teeth surface. It can be concluded that natural materials can potentially be alternative teeth remineralization agents.
Effects of Higher Lattice Temperatures on 2D MC Simulation of Grain Growth and its Inhibition

Extensive simulations applying the Monte Carlo Potts model were carried out on a twodimensional square lattice to evaluate the influence of higher lattice temperatures on grain growth kinetics and the Zener limit. A wide range of simulation temperatures (KTs) were applied on a matrixof size 10002 with Q-state 64. They were then dispersed with a wide range of second-phase particles and ran to 100,000 Monte Carlo steps. The critical temperature for a square lattice with eight nearest neighbors (8 NN) was established as KTs = 0.4, after evaluating several growth parameters, undersimulated thermal conditions. Simulations were then next run to stagnation, for higher temperatures up to the critical value of KTs, and various growth parameters were computed in the pinned state. The Zener limit was found to scale with the square root of the surface fraction of second-phase particleswhile varying exponentially with its fraction lying on the grain boundaries.
Prediction of TTR Diagrams via Physically Based Creep Simulations of Martensitic 9-12% Cr-Steels

This work deals with the prediction of time-to-rupture (TTR) diagrams of martensitic 9-12% Cr steels. Martensitic 9-12% Cr steels are state of the art materials for powerplants due to their high creep strength and oxidation resistance. Since the experimental determination of TTR diagrams is costly and time-expensive (minimum 10 years), it is of particular interest to be able to model TTR diagrams and gradually replace experiments. Here, we approach the question to what extent we can generate a TTR diagram of a material out of a fraction of experimental results plus detailed understanding of the underlying microstructural/physical phenomena during creep. Our model is based on dislocation creep and includes multiple interactions between the microstructural constituents. We show the applicability of our approach by reproducing a TTR diagram of the well-known material P92. Input parameters are basic material data from literature, the starting microstructure before creep, chemical composition, some model parameters determined on the similar material P91, and one single creep curve of P92. The precipitate evolution is simulated by the software MatCalc, the other microstructural constituents (dislocation densities, subgrain boundaries etc.) by our creep model. By varying the stress between individual creep simulations whilst keeping all input parameters (starting microstructure, temperature and material parameters) constant, we produce multiple creep curves and thus generate the complete dataset for a TTR diagram. The model is of particular interest when it comes to the development of new materials, as the application range of these materials can be estimated quickly and with good reproducibility.