Miracle-dz/UniFAR-FTUs huggingface dataset:
Relationship between Adherence to the Mediterranean Diet and Body Composition with Physical Fitness Parameters in a Young Active Population

The current study aimed at analyzing the relationship between body composition, adherence to the Mediterranean diet (MD), and physical fitness (PF) in a young active population. A total of 1198 athletes (boys = 875; girls = 323) enrolled in different municipal sports schools participated in this study. Data on adherence to the MD (KIDMED questionnaire), anthropometric measurements, and PF (20 m shuttle run test, handgrip strength, vertical jump and forced spirometry) were collected. Results show that the pubertal boys had a higher score in the KIDMED test than the prepubertal ones (+0.38, p = 0.28). Moreover, boys with better adherence to the MD had significantly higher results in handgrip strength (+12.20 regarding low MD group and +9.13 regarding medium MD group, p < 0.05), as well as in forced vital capacity (FVC) (+0.66 regarding low MD group and 0.29 regarding medium MD group, p < 0.05). No differences were found in the girls. Finally, the result of the KIDMED test is a variable with a positive and significant relationship with cardiorespiratory fitness, along with the FVC, percentage of fat mass, and performance in the vertical jump (p < 0.05). It is concluded that adherence to the MD could show a relationship with various PF variables in boys and could be a predictor of cardiorespiratory fitness in both cases.
The Articulation Handicap Scale with 12 items (AHS-12): a short form of the Articulation Handicap Index (AHI)

Abstract Objective The objective is to produce a short instrument for measuring the subjectively experienced articulation handicap, i.e. the extent to which physical, functional, and emotional handicaps caused by a physical deficit are subjectively experienced. Methods The items for the short instrument were selected from the 30 items of the Articulation Handicap Index (AHI) by removing items on the basis of item-total correlations using data from 113 cancer survivors. Reliability and validity of the sum score of the corresponding item selection were used for determining the optimal item selection. This optimal item selection was compared with the AHI in an RCT with patients undergoing phoniatric routine diagnostics. Results With only 12 items left, the measurement instrument was still as reliable and valid as the AHI. With less than 12 items, reliability and validity decreased. In the RCT between the AHI (n = 41) and the 12-item selection (n = 40), reliability and validity of both instruments were the same, but processing times differed (AHI; 3.84 min; 12-item selection: 2.02 min). Conclusion The 12-item selection, further referred to as the Articulation Handicap Scale with 12 items (AHS-12), provides nearly as much information as the original AHI.
Predictive Modeling to Determine Functional Outcomes After Arthroscopic Rotator Cuff Repair

Background: Arthroscopic rotator cuff repair (ARCR) is one of the most commonly performed orthopaedic surgical procedures; however, patient-reported outcomes have varied greatly in the literature. Purpose: To identify preoperative factors that affect outcomes and to develop prognostic tools for predicting functional outcomes in future ARCR cases. Study Design: Cohort study; Level of evidence, 3. Methods: Patients were included who underwent ARCR for repairable full-thickness rotator cuff tears with at least 2 years of follow-up. Twelve predictors were entered as candidate predictors in each model: age, sex, workers’ compensation (WC) status, previous cuff repair, tear size, tear shape, multiple-tendon involvement, tendon stump length, Goutallier classification, critical shoulder angle, length of follow-up, and baseline subjective outcomes score. Postoperative American Shoulder and Elbow Surgeons (ASES), 12-Item Short Form Health Survey Physical Component Summary (SF-12 PCS), QuickDASH (short version of Disabilities of the Arm, Shoulder and Hand), and patient satisfaction were each modeled through proportional odds ordinal logistic regression. Model results were presented with marginal covariate effect plots and predictive nomograms. Results: Overall, 552 shoulders fit inclusion criteria. The mean age at surgery was 60.2 years (range, 23-81 years). Twenty-five (4.5%) shoulders underwent revision cuff repair or reverse arthroplasty at a mean 1.9 years (range, 0.1-7.9 years) postoperatively. Overall, 509 shoulders were eligible for follow-up, and minimum 2-year postoperative patient-reported outcomes were obtained for 449 (88.2%) at a mean 4.8 years (range, 2-11 years). The ASES score demonstrated significant improvement from pre- to postoperative median (interquartile range): 58 (44.9-71.6) to 98.3 (89.9-100; P < .001). Women demonstrated significantly higher 2-year reoperation rates than men (5.8% vs 1.6%; odds ratio, 2.8 [95% CI, 0.73-9.6]; P = .023). Independently significant predictors for lower postoperative ASES scores included previous ARCR (P < .001), female sex (P < .001), and a WC claim (P < .001). Significant predictors for worse QuickDASH scores included WC claim (P < .001), female sex (P < .001), previous ARCR (P = .007), and ≥7 years of follow-up time. Significant predictors for lower SF-12 PCS scores included WC claim (P < .001), female sex (P = .001), and lower baseline SF-12 PCS. Last, significant independent predictors of patient satisfaction included previous ARCR (P = .004), WC claim (P = .011), female sex (P = .041), and age (P = .041). Conclusion: Excellent clinical outcomes and low failure rates were obtained after ARCR by using careful patient selection and modern surgical techniques for ARCR. Female sex, WC claim, and previous ARCR were significant predictors of poorer outcomes in at least 3 patient-reported outcome models. Prognostic nomograms were developed to aid in future patient selection, clinical decision making, and patient education.
Effects of Suspended Sediments on Aquatic Ecosystems

Abstract Resource managers need to predict effects of pollution episodes on aquatic biota, and suspended sediment is an important variable in considerations of freshwater quality. Despite considerable research, there is little agreement on environmental effects of suspended sediment as a function of concentration and duration of exposure. More than 70 papers on the effects of inorganic suspended sediments on freshwater and marine fish and other organisms were reviewed to compile a data base on such effects. Regression analysis indicates that concentration alone is a relatively poor indicator of suspended sediment effects (r 2 = 0.14, NS). The product of sediment concentration (mg/L) and duration of exposure (h) is a better indicator of effects (r 2 = 0.64, P < 0.01). An index of pollution intensity (stress index) is calculated by taking the natural logarithm of the product of concentration and duration. The stress index provides a convenient tool for predicting effects for a pollution episode of known int.
Are the nutrient and textural properties of Australian commercial infant and toddler foods consistent with infant feeding advice?

Abstract Infant feeding guidelines worldwide recommend first foods to be Fe rich with no added sugars and that nutrient-poor discretionary foods are to be avoided. Feeding guidelines also recommend exposing infants to a variety of foods and flavours with increasingly complex textures. Here, we compare nutritional and textural properties of commercial infant and toddler foods available in Australia with established infant feeding guidelines. Nutrition information and ingredient lists were obtained from food labels, manufacturer and/or retailer websites. In total, 414 foods were identified, comprising mostly mixed main dishes, fruit and vegetable first foods and snacks. Most products were poor sources of Fe, and 80 % of first foods were fruit-based. Half of all products were purées in squeeze pouches, and one-third of all products were discretionary foods. The nutritional content of many products was inconsistent with guidelines, being low in Fe, sweet, smooth in consistency or classified as discretionary. Reformulation of products is warranted to improve Fe content, particularly in mixed main dishes, expand the range of vegetable-only foods and textural variety. Greater regulatory oversight may be needed to better inform parents and caregivers. Frequent consumption of commercial baby foods low in Fe may increase the risk of Fe deficiency. Excessive consumption of purées via squeeze pouches may also have implications for overweight and obesity risk.
Prevalence of gastro-intestinal helminths in school children in Mbaukwu, Anambra State, Nigeria

A study was conducted to determine the prevalence of gastro-intestinal helminth parasites among 514 pupils aged 5-16 years in five primary schools in Mbaukwu, Awka South Local Government Area, Anambra State, Nigeria. Structured questionnaire was used to determine the socio-economic factors enhancing the transmission of the parasites. Six helminth parasites were isolated, namely, Hookworm (37.3%), Ascaris lumbricoides (33.6%), Trichuris trichiura (11.7%) Strongyloides stercoralis (8.2%), Taenia spp (6.90/0) and Schistosoma mansoni (2.8%). Multiple parasitism were also encountered. Pupils in the agegroup 9-12 years had the highest infection rate (41.0%) followed by those in age-group 5-9 (40.1%). Infection rate was higher among (p>0.05) females than males though not statistically significant. Infection was higher among those whose parents were farmers and traders than those of civil servants. Infection was also higher among pupils who used nearby bushes for defaecation than those who use pit latrine and water. Sanitation should be encouraged in order to control the disease since the high prevalence was found to be associated with unsanitary habits. There is the need to incorporate the control of intestinal helminthiasis into Expanded Programme on Immunization (EPI). Keywords : helminth, parasites, prevalence, Mbaukwu. Nigerian Journal of Parasitology Vol. 29 (1) 2008 pp. 15-19
Trends and Utilization of Inpatient Palliative Care Among Patients With Metastatic Bladder Cancer

Objective: To explore the trends and utilization of palliative care (PC) service among inpatients with metastatic bladder cancer (MBC). Methods: A retrospective, cross-sectional analysis was performed using data from the 2003 to 2014 National Inpatient Sample. Palliative care was identified through International Classification of Diseases, Ninth Revision code V66.7. Demographics, comorbidities, hospital characteristics, tumor-related, and treatment-related factors were compared between patients with and without PC. Multivariable logistic regression was used to explore predictors of PC use. Results: Among 131 852 patients with MBC, 13 224 (10.03%) received PC. Rate of PC increased from 2.49% in 2003 to 28.39% in 2014 (P < .0001). Similarly, rate of PC in decedents increased from 7.02% in 2003 to 54.86% in 2014 (P < .0001). Patients receiving PC were older, tendered to be white, had more comorbidities, and higher all-patient refined diagnosis-related group mortality risk. Predictors of PC included age (odds ratio [OR]: 1.02; 95% CI: 1.01-1.02; P < .0001), Medicaid (OR: 1.87; 95%.CI: 1.54-2.26; P < .0001), and private (OR: 1.61; 95% CI: 1.40-1.84; P < .0001) insurance, hospitals in the West (OR: 1.33; 95% CI: 1.10-1.61; P = .0032), and Mid-west (OR: 1.46; 95% CI: 1.22-1.75; P = .0032), major (OR: 1.32; 95% CI: 1.11-1.49; P < .0001), and extreme (OR: 2.37; 95% CI: 2.04-2.76; P < .0001) mortality risk. Chemotherapy and mechanical ventilation were related with lower odds of PC use. Palliative care predictors in the decedents were similar to those in overall patients with bladder cancer. Conclusions: Palliative care encounter in MBC shows an increasing trend. However, it still remains very low. Disparities in PC use covered age, insurance, and hospital characteristics among metastatic bladder cancer in the United States.
Can hippotherapy make a difference in the quality of life of children with cerebral palsy? A pragmatic study

ABSTRACT Objective: To determine if the addition of 12 weekly therapy sessions, incorporating hippotherapy as the primary intervention to each child’s usual therapy program, will improve balance, participation, and quality of life. Methods: Pragmatic, multi-center, randomized, controlled trial of 13 children with cerebral palsy (CP), ages 3 to 6 years. A treatment group received 12 weeks of weekly hippotherapy intervention in addition to their usual therapy. A control group continued with their usual therapy only. Assessments were completed for the treatment group pre-intervention (P0), post intervention (P1), and 12 weeks post no intervention (P2). Control group assessments occurred in the same timeframe: baseline, 12 weeks and 24 weeks. Results: The only significant difference between the groups, post intervention, was on the Pediatric Balance Scale (PBS). Within group analysis showed no significant changes for the control group between any pretest/posttest measures. The treatment group demonstrated significant improvement on the PBS (P0-P1, p = .02; P0-P2, p = .02) and Activities Scale for Kids (P0-P1, p = .02; P0-P2, p = .02) with delayed improvement on the 1 Minute Walk Test (P1-P2, p = .02) and Pediatric Quality of Life – CP Module (P0-P2, p = .03). Conclusions: Improvements in balance in children with CP may promote increased participation and quality of life when hippotherapy is added to their treatment plan.
Needs of Migrant Arab Muslim Childbearing Women in the United Kingdom

Introduction: This study aims to examine the challenges faced by migrant Arab Muslim women in accessing maternity services and to suggest ways to improve the childbirth experience for them. Methodology: An interpretive ontological–phenomenological perspective guided by the philosophical tenets of Heidegger was used to examine the childbirth experiences of Arab Muslim women. Results: The sample size was 24 in-depth semistructured audiotaped interviews with eight women in the United Kingdom. The “Vulnerable Woman” was the main theme of our findings, which was discussed in five subthemes: language exclusion, discrimination and prejudice, bureaucracy and “stiff upper lip,” conflicting ideology, and the conventional as strange. Conclusions: Maternity care should be culturally competent and emphasize the importance of recognizing differences as well as creating trusting relationships. At the same time, midwives should be aware of the dangers of labeling women because of their cultural and religious beliefs.
Synchronous Multiple Breast Cancers—Do We Need to Reshape Staging?

Background and Objectives: Current recommendations and treatment regimens in breast cancer are a reflection of its heterogeneity on multiple levels including histological subtypes, grading, molecular profiling, and numerous prognostic indices. Although based on extensive research, current guidelines are not explicit in the case of surgical specimens showing various degrees of mismatch between different parts of the same tumor and even more so between multicentric lesions. Synchronous breast cancer is the ideal prototype for studying inter- and intra-tumoral heterogeneity, therefore we envisaged that a study on patients with multicentric and multifocal lesions could contribute to the reshaping of the staging, prognosis, and treatment of breast malignancies. Material and Methods: A prospective observational study was conducted between January 2013 and May 2017 on 235 patients diagnosed with breast cancer (BC) and surgically treated at Emergency University Hospital, Bucharest. Thirty-seven patients had multiple breast tumors and were eligible for assessment of the heterogeneity of their lesions. Results: 6 were multicentric and 31 multifocal. The number of foci varied from 2 to 11. We encountered numerous mismatches between the index and the secondary tumors, as follows: 3 cases (8.1%) with histopathological mismatch, 13 (35.1%) with different grades of differentiation, 11 (29.8%) with ER (Estrogen Receptors) status mismatch, 12 (32.4%) with PR (Progesterone Receptors) status mismatch, 8 (21.6%) with molecular phenotype mismatch, and 17 (45.9%) cases with variable Ki-67. After careful analysis of index and secondary tumors, apart from the mismatches reported above, we discovered that the secondary tumors were actually dominant in 5 cases (13.5%), and therefore at least those cases had to be reclassified/restaged, as the supplementary data commanded changes in the therapeutic decision. Conclusions: For synchronous breast tumors, the current Tumor-Node-Metastasis (TNM) staging system ignores not only the histopathological and immunohistochemical characteristics of the secondary foci, but also their size. When secondary lesions are more aggressive or their cumulative mass is significantly bigger than that of the index tumor, the treatment plan should be adapted accordingly. We believe that information obtained from examining secondary foci in synchronous breast cancer and assessment of the cumulative tumoral mass should be reflected in the final staging and definitive treatment. The clinical benefit of staging the patients based on the most aggressive tumor and the cumulative tumoral burden rather than according to the biggest single tumor, will avoid under-treatment in cases with multifocal/multicentric BC displaying intertumoral mismatch.
Cellular Localization of gdnf in Adult Zebrafish Brain

Glial cell line-derived neurotrophic factor (GDNF) was initially described as important for dopaminergic neuronal survival and is involved in many other essential functions in the central nervous system. Characterization of GDNF phenotype in mammals is well described; however, studies in non-mammalian vertebrate models are scarce. Here, we characterized the anatomical distribution of gdnf-expressing cells in adult zebrafish brain by means of combined in situ hybridization (ISH) and immunohistochemistry. Our results revealed that gdnf was widely dispersed in the brain. gdnf transcripts were co-localized with radial glial cells along the ventricular area of the telencephalon and in the hypothalamus. Interestingly, Sox2 positive cells expressed gdnf in the neuronal layer but not in the ventricular zone of the telencephalon. A subset of GABAergic precursor cells labeled with dlx6a-1.4kbdlx5a/6a: green fluorescence protein (GFP) in the pallium, parvocellular preoptic nucleus, and the anterior and dorsal zones of the periventricular hypothalamus also showed expression with gdnf mRNA. In addition, gdnf signals were detected in subsets of dopaminergic neurons, including those in the ventral diencephalon, similar to what is seen in mammalian brain. Our work extends our knowledge of gdnf action sites and suggests a potential role for gdnf in adult brain neurogenesis and regeneration.
Codon Pairs are Phylogenetically Conserved: A comprehensive analysis of codon pairing conservation across the Tree of Life

Identical codon pairing and co-tRNA codon pairing increase translational efficiency within genes when two codons that encode the same amino acid are translated by the same tRNA before it diffuses from the ribosome. We examine the phylogenetic signal in both identical and co-tRNA codon pairing across 23 428 species using alignment-free and parsimony methods. We determined that conserved codon pairing typically has a smaller window size than the length of a ribosome, and codon pairing tracks phylogenies across various taxonomic groups. We report a comprehensive analysis of codon pairing, including the extent to which each codon pairs. Our parsimony method generally recovers phylogenies that are more congruent with the established phylogenies than our alignment-free method. However, four of the ten taxonomic groups did not have sufficient orthologous codon pairings and were therefore analyzed using only the alignment-free methods. Since the recovered phylogenies using only codon pairing largely match phylogenies from the Open Tree of Life and the NCBI taxonomy, and are comparable to trees recovered by other algorithms, we propose that codon pairing biases are phylogenetically conserved and should be considered in conjunction with other phylogenomic techniques.
Impact of Atrazine on Periphyton in Freshwater Enclosures and Some Ecological Consequences

The herbicide atrazine inhibited production of periphyton within limnocorrals (in situ aquatic enclosures) and altered the composition of the periphyton community. On two occasions, 6 wk apart, three limnocorrals were treated with a surface application of atrazine equivalent to a nominal enclosure concentration of 100 μg∙L−1 During the first atrazine pulse, the Cyanophyta disappeared and organic matter decreased to values significantly less than those within three control enclosures. Within 3 wk of the second atrazine application, a 36–67% reduction in organic matter, chlorophyll, and algal biomass and a significant decrease in the rate of carbon assimilation were evident. These events coincided with a decrease in number of certain Chlorophyta species, although other Chlorophyta species increased in number. The Bacillariophyceae maintained biomass levels greater than those in the controls for 9 wk after the second atrazine application. Total limnocorral periphyton production was greater than that of the p.