Miracle-dz/UniFAR-FTUs huggingface dataset:
Validity and Reliability of Hip Strength Assessment Using a Frame-Stabilized Dynamometer System Device

ABSTRACT The purpose was to evaluate the intra- and inter-session reliability of hip isometric strength assessment using a frame-stabilized dynamometer (FSD) and to compare the results in the hip adduction (ADD) and abduction (ABD) strength assessment using handheld dynamometer (HHD). Twenty participants (24.2 [2.6] years, 69.3 [10.0] kg) underwent testing on an FSD (ADD and ABD short and long-lever, internal [IR] and external rotation [ER] tests) and using an HHD (ADD and ABD long-lever tests). Analysis revealed excellent (ICC2.k > 0.90) relative intra-set and inter-set reliability for two visits and good reliability for test-retest results (ICC2.1 0.79–0.90), regardless of the test. Among the tests, SEM and MDC were the highest for the IR and ER results. In comparison with HHD, long-lever ADD strength was higher and long-lever ABD strength was lower when measured using FSD. Although both measurements have been shown to be highly reliable, the discrepancy between the devices exists.
Relationship between endoscopic gastric abnormalities and colorectal polyps: a cross-sectional study based on 33439 Chinese patients

Background: No study on the relationship between common abnormalities of the upper digestive tract and colorectal polyps (CPs) has been conducted. Methods: 33439 patients were enrolled in this cross-sectional study, of which 7700 had available Helicobacter pylori (H.pylori) information. All participants underwent colonoscopy and esophagogastroduodenoscopy (EGD) simultaneously or within six months at Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology from January 2015 to November 2021. The study assessed whether the risk of CPs was affected by the following gastroesophageal diseases: atrophic gastritis (AG), gastric polyps, Barrett's esophagus and reflux esophagitis, bile reflux, gastric ulcer, gastric mucosal erosion, superficial gastritis, and gastric H.pylori infection. The crude and adjusted odds ratios (ORs) of H.pylori on the occurrence of CPs were computed by logistic regression. Additionally, we also evaluated whether AG had an impact on the relationship between H.pylori infection and CPs. Results: A total of 10600 cases (31.7%) were diagnosed as CPs. Multivariate logistic analysis showed that age, male (OR, 1.80; 95% confidence interval [CI], 1.61 to 2.02), gastric polyps (OR, 1.61; 95% CI, 1.05 to 2.46 for hyperplastic polyps; OR, 1.45; 95% CI, 1.09 to 1.94 for fundic gland polyps), H.pylori infection (OR, 1.21; 95% CI, 1.07 to 1.37) and atrophic gastritis (OR, 1.38; 95% CI, 1.21 to 1.56) were independent risk factors for colorectal polyps. Moreover, the combined effect of H.pylori infection and AG was slightly greater than the sum of their individual effects on the risk of CPs, but there was no additive interaction between them. Conclusions: Gastric conditions including gastric polyps, H.pylori infection, and AG increased the risk of CPs. However, Barrett's esophagus and reflux esophagitis, bile reflux, erosive gastritis, gastric ulcer, and superficial gastritis might not have relationship with CPs occurrence.
Using Dome C for moderate resolution imaging spectroradiometer calibration stability and consistency

Currently, there are two nearly identical moderate resolution imaging spectroradiometer (MODIS) instruments operated in space: one on the Terra spacecraft launched in December 1999 and another on the Aqua spacecraft launched in May 2002. MODIS has 36 spectral bands with wavelengths covering from visible (VIS) to long-wave infrared (LWIR). Since launch, MODIS observations and data products have significantly enabled studies of changes in the Earth system of land, oceans, and atmosphere. In order to maintain its on-orbit calibration and data product quality, MODIS was built with a comprehensive set of on-board calibrators. MODIS reflective solar bands (RSB) are calibrated on-orbit by a system that consists of a solar diffuser (SD) and a solar diffuser stability monitor (SDSM) on a regular basis. Its thermal emissive bands (TEB) calibration is executed on a scan-by-scan basis using an on-board blackbody (BB). The MODIS Characterization Support Team (MCST) at NASA/GSFC has been responsible for supporting sensor calibration and characterization tasks from pre-launch to post launch. In this paper, we describe current MCST efforts and progress made to examine sensor stability and inter-calibration consistency using observations over Dome Concordia, Antarctica. Results show that this site can provide useful calibration reference for Earth-observing sensors.
Cytogenetics, Typification, Molecular Phylogeny and Biogeography of Bentinckia (Arecoideae, Arecaceae), an Unplaced Indian Endemic Palm from Areceae

Simple Summary Bentinckia is an Indian endemic genus belonging to the tribe Areceae (Arecaceae). This genus contains two species, B. condapanna and B. nicobarica, and both need to be conserved as they come under the threatened category. Bentinckia, along with nine genera, remains unplaced in Areceae. The members of the unplaced Areceae show characteristics corresponding to all the subtribes. Therefore, morphologically it is difficult to assign any subtribes to these genera. Many molecular phylogenetic analyses have reported the relationships within Areceae. However, all of these are unable to show confident position and support for the species. In the present article, we constructed the molecular phylogeny of Areceae based on an appropriate combination of chloroplast and nuclear loci that satisfactorily depicts the phylogenetic positions of all species from Areceae. Phylogeny and evolutionary history disclose that Bentinckia together with unplaced Clinostigma and Cyrostachys show a close relationship with the subtribe Arecinae and might have originated in Eurasia and India. In addition, this study reports a taxonomic revision of Bentinckia. In addition, it provides a new chromosome number (cytotype), i.e. 2n = 30 for B. condapanna. This study will form the very basis for assessing and refining the systematic position of all the species from the tribe Areceae. Abstract Bentinckia is a genus of flowering plants which is an unplaced member of the tribe Areceae (Arecaceae). Two species are recognized in the genus, viz. B. condapanna Berry ex Roxb. from the Western Ghats, India, and B. nicobarica (Kurz) Becc. from the Nicobar Islands. This work constitutes taxonomic revision, cytogenetics, molecular phylogeny, and biogeography of the Indian endemic palm genus Bentinckia. The present study discusses the ecology, morphology, taxonomic history, distribution, conservation status, and uses of Bentinckia. A neotype was designated for the name B. condapanna. Cytogenetical studies revealed a new cytotype of B. condapanna representing 2n = 30 chromosomes. Although many phylogenetic reports of the tribe Areceae are available, the relationship within the tribe is still ambiguous. To resolve this, we carried out Bayesian Inference (BI) and Maximum Likelihood (ML) analysis using an appropriate combination of chloroplast and nuclear DNA regions. The same phylogeny was used to study the evolutionary history of Areceae. Phylogenetic analysis revealed that Bentinckia forms a clade with other unplaced members, Clinostigma and Cyrostachys, and together they show a sister relationship with the subtribe Arecinae. Biogeographic analysis shows Bentinckia might have originated in Eurasia and India.
In Vitro Binding Effects of the Ecdysone Receptor−Binding Domain and PonA in Plutella xylostella

Both insect ecdysone receptors and ultraspiracle belong to the nuclear receptor family. They form a nanoscale self-assembling complex with ecdysteroids in cells, transit into the nucleus, bind with genes to initiate transcription, and perform specific biological functions to regulate the molting, metamorphosis, and growth processes of insects. Therefore, this complex is an important target for the development of eco-friendly insecticides. The diamondback moth (Plutella xylostella) is a devastating pest of cruciferous vegetable crops, wreaking havoc worldwide and causing severe economic losses, and this pest has developed resistance to most chemical insecticides. In this study, highly pure EcR and USP functional domains were obtained by constructing a prokaryotic expression system for the diamondback moth EcR and USP functional domain genes, and the differences between EcR and USP binding domain monomers and dimers were analyzed using transmission electron microscopy and zeta potential. Radioisotope experiments further confirmed that the binding affinity of PonA to the EcR/USP dimer was enhanced approximately 20-fold compared with the binding affinity to the PxGST−EcR monomer. The differences between PonA and tebufenozide in binding with EcR/USP were examined. Molecular simulations showed that the hydrogen bonding network formed by Glu307 and Arg382 on the EcR/USP dimer was a key factor in the affinity enhancement. This study provides a rapid and sensitive method for screening ecdysone agonists for ecdysone receptor studies in vitro.
An Magnetic-Targeting Nano-Diagnosis and Treatment Platform for TNBC

Purpose In this experiment, we constructed a magnetic targeting nano-diagnosis and treatment platform of doxorubicin (DOX) combined with iron nanoparticles, and explored their application value and mechanism in the treatment of Triple Negative Breast Cancer (TNBC), as well as its new diagnosis and treatment mode in Magnetic Resonance Imaging (MRI). Patients and Methods Hollow mesoporous nanoparticles (HFON) were synthesized by solvothermal method, and loaded the drug DOX (DOX@HFON) to treat TNBC. The experiments in vivo and in vitro were carried out according to the characteristics of the materials. In vitro experiments, the killing effect of the drug on cells was verified by cell viability CCK8, ROS generation level, LPO evaluation and flow cytometry; the MRI effect and targeted anti-tumor therapy effect were studied by in vivo experiments; then the tumor tissue sections were detected by Ki-67, CD31, ROS, LPO and TUNEL immunofluorescence detection; H&E staining and blood biochemical tests were used to evaluate the biosafety of the materials. Results Through a series of characterization tests, it is confirmed that the nano-materials prepared in this experiment have positive drug loading properties. MDA-MB-231 cells had great phagocytic ability to DOX@HFON under Confocal Laser Scanning Microscope (CLSM). Experiments in vitro confirmed that DOX and Fe were released and concentrated in cells, and a large number of ROS production and induction of LPO were detected by DCFH-DA and C11-BODIPY probes in cells. Apoptosis experiments further confirmed that DOX@HFON induced apoptosis, autophagy and ferroptosis. In the vivo experiment, the anti-tumor therapy effect of MAGNET@DOX@HFON group was the most significant, and in MRI also proved that the drug had great tendency and imaging ability in tumor tissue. Conclusion The new magnetic targeting nano-diagnosis and treatment platform prepared in this experiment is expected to become a new treatment model for TNBC.
The Impacts of the COVID-19 Pandemic on Doctor of Physical Therapy Students: A National Survey

Supplemental Digital Content is Available in the Text. Introduction. Since the lockdown in March 2020, the COVID-19 pandemic has inevitably affected all individuals across the world. The purpose of this study was to determine the perceived impacts of the pandemic on doctor of physical therapy (DPT) students and if there were any statistically significant differences based on minority status, gender, or class standing. Review of Literature. Literature suggested that DPT students experienced negative impacts of the pandemic on academic success and mental health. However, there is a lack of comprehensive understanding of the perceived physical, mental, financial, and academic impacts of the COVID-19 pandemic by physical therapist students nationally. Subjects. Convenience sampling was used to recruit all students enrolled in physical therapist programs in the United States. Methods. The research design was a cross-sectional survey administered electronically using the Alchemer survey platform with 12 Likert scale items compiled in the physical, mental, financial, and academic domains. All items were designed to evaluate the perceived impacts of the pandemic on a 5-point scale from 1 (strongly disagree) to 5 (strongly agree). Results. A total of 1,230 completed responses were received. The mean responses were 3.45 (SD 1.12), 3.48 (SD 0.92), 2.74 (SD 1.03), and 3.33 (SD 0.93) for the physical, mental, financial, and academic domains, respectively. No significant difference was found based on minority status. A statistically significant difference was found in the mental domain, with female students perceiving a more negative impact by the pandemic. First-year students reported a significantly higher negative impact in the physical domain compared with second-year students. The perceived impact in the academic domain was significantly higher for both first- and second-year students than third-year students. Conclusions. Developing and promoting access to campus and community resources to address the challenges caused by the COVID-19 pandemic is critical to facilitating student success during and after the pandemic.
Ultra-fast multiple tunnelling of electromagnetic X-waves

A study is provided of the transmission of a three-dimensional electromagnetic X-wave undergoing frustrated total internal reflection on the upper surface of a multi-layered structure. The stratified structure consists of successive layers alternately allowing the transmission of evanescent and free-propagation components. It is shown that the peak of an X-wave is transmitted through these successive layers at an ultra-fast speed. Under certain conditions, the total traversal time through all successive evanescent and free-propagation sections appears to be less than zero. The peak of the transmitted pulse emerges from the stack before the incident peak reaches the front surface of the stratified structure. Conditions for the materialization of this ultra-fast multiple tunnelling of pulses are pointed out and their consequences and limitations are discussed.
Large Eddy Simulation of the Diurnal Cycle in Southeast Pacific Stratocumulus

Abstract This paper describes a series of 6-day large eddy simulations of a deep, sometimes drizzling stratocumulus-topped boundary layer based on forcings from the East Pacific Investigation of Climate (EPIC) 2001 field campaign. The base simulation was found to reproduce the observed mean boundary layer properties quite well. The diurnal cycle of liquid water path was also well captured, although good agreement appears to result partially from compensating errors in the diurnal cycles of cloud base and cloud top due to overentrainment around midday. At all times of the day, entrainment is found to be proportional to the vertically integrated buoyancy flux. Model stratification matches observations well; turbulence profiles suggest that the boundary layer is always at least somewhat decoupled. Model drizzle appears to be too sensitive to liquid water path and subcloud evaporation appears to be too weak. Removing the diurnal cycle of subsidence had little effect on simulated liquid water path. Simulations.
A new design for high stability pressure-controlled ventilation for small animal lung imaging

We have developed a custom-designed ventilator to deliver a stable pressure to the lungs of small animals for use in imaging experiments. Our ventilator was designed with indepen- dent pressure vessels to separately control the Peak Inspiratory Pressure (PIP) and Positive End Expiratory Pressure (PEEP) to minimise pressure fluctuations during the ventilation process. The ventilator was computer controlled through a LabVIEW interface, enabling experimental manip- ulations to be performed remotely whilst simultaneously imaging the lungs in situ. Mechanical ventilation was successfully performed on newborn rabbit pups to assess the most effective venti- lation strategies for aerating the lungs at birth. Highly stable pressures enabled reliable respiratory gated acquisition of projection radiographs and a stable prolonged (15 minute) breath-hold for high-resolution computed tomography of deceased rabbit pups at different lung volumes.
Analysis of Random Cascades Using Space-Scale Correlation Functions

We introduce a formalism that allows us to study space-scale correlations in multiscale processes. This method, based on the wavelet transform, is particularly well suited to study multiplicative random cascade processes for which the correlation functions take a very simple expression. This two-point space-scale statistical analysis is illustrated on some pedagogical examples and then applied to fully developed turbulence data.
Interfaces and traps in pentacene field-effect transistor

The equivalent circuit parameters for a pentacene organic field-effect transistor are determined from low frequency impedance measurements in the dark as well as under light illumination. The source-drain channel impedance parameters are obtained from Bode plot analysis and the deviations at low frequency are mainly due to the contact impedance. The charge accumulation at organic semiconductor–metal interface and dielectric–semiconductor interface is monitored from the response to light as an additional parameter to find out the contributions arising from photovoltaic and photoconductive effects. The shift in threshold voltage is due to the accumulation of photogenerated carriers under source-drain electrodes and at dielectric–semiconductor interface, and also this dominates the carrier transport. The charge carrier trapping at various interfaces and in the semiconductor is estimated from the dc and ac impedance measurements under illumination.
Understanding lead and mercury adsorption by post-synthetically modified linkers in UiO-66 MOF. A computational theoretical study

ABSTRACT UiO-66 Metal-Organic framework (MOF) has been highlighted since its synthesis for its stability and many potential applications. Lead (II) and mercury (II) water remediation are among them. In the present work, we used density functional theory calculations, cluster models, and density analysis tools to study the lead and mercury adsorption mechanism of modified UiO-66. We have included the SH (thiol), NCS (isothiocyanate), NMeTU (N-methylthiourea) and DMTD (2,5-dimercapto-1,3,4-thiadiazole) linker groups. The results show a clear trend in capturing both metals: DMTD > NMeTU > SH > NCS. For mercury adsorption, little energy difference for DMTD (bidentate) and NMeTU (monodentate) is found, while for lead, this gap is greater. Inspection of charges and descriptors as softness in conceptual DFT showed the relevance of charge transfer in mercury capture by NMeTU, making this interaction almost as strong as the bidentate fashion through sulfur and nitrogen atoms in DMTD. Lead capture shows charge transfers of lesser magnitude, so the preferred interaction fashion is bidentate. Electronic density difference maps show qualitative visualization of results and are consistent with interaction energies. Through non-covalent interaction (NCI) analysis, it was possible to conclude that at DMTD, the interaction for both metals was stronger with nitrogen atom than sulfur.
Cytomegalovirus Specific Cell-Mediated Immunity Status in Women with Preeclampsia: A Case-Control Study

Background: Preeclampsia, a pregnancy-specific complication, has been associated with cytomegalovirus (CMV) infection in observational studies. CMV-specific T cell response plays a major role in viremia clearance. We explored whether CMV-specific cell-mediated immunity (CMI) status is associated with preeclampsia in pregnant women. Materials and Methods: CMV-specific CMI was assessed using CMV-QuantiFERON (QF-CMV) assay in plasma serum of 35 women with preeclampsia as well as 35 normal pregnant controls, retrospectively. Participants were matched for gestational age in a 1:1 ratio. The proportion of reactive results, the mean value of interferon-gamma (IFN-γ) level produced in mitogen and antigen tubes were compared between the cases and controls through Chi-square and Wilcoxon rank-sum tests, respectively. The odds ratio and confidence interval were calculated as well. Results: No significant differences observed between demographic characteristics of the case and control groups. The QF-CMV assay turned reactive (QF-CMV [ + ]) Women with preeclampsia had lower mean IFN-γ levels in antigen tube compared with normal pregnant controls. There were no statistically significant differences in the value of mitogen tube between case and controls women with suppressed CMV-CMI were 6.3 times more likely to have preeclampsia. This result even strengthened after adjustment for age, gestational age, and gravidity. Conclusions: Our findings support an association between suppressed CMV-specific CMI and preeclampsia.
Estimation of Inventory Re-Order Levels Using the Bootstrap Statistical Procedure

It can be difficult to set the reorder point in an inventory system because often one does not have much knowledge of the lead-time demand (LTD)distribution. A frequent practice is to assume a “standard” distribution, such as the Normal. The reorder point is then taken as the p-th fractile of that standard distribution, where (1 −p) is the specified probability of stockout during a replenishment cycle. When the desired service level p is high and the “true” LTD distribution is skewed, previous research has shown that the reorder point and inventory costs are strongly affected by the shape of the assumed LTD distribution. Ideally, no assumptions about this distribution should be necessary. One such “distribution-free” approach is the bootstrap procedure. Beginning with a single sample W = {x1x2,…,xn} of lead-time demand, the bootstrap repeatedly samples with replacement from W, A family of bootstrap samples of size n is thereby created, each sample furnishing an estimate Xp∗ of the p-th fractile of the LTD.
Text complexity and variety factors in narrative retelling and narrative comprehension among Arabic-speaking preschool children

The current study investigates narrative retelling and comprehension among 30 native Arabic-speaking preschool children with a mean age of 5:10. Narrative features of text-complexity (less-complex and more-complex episodic structure) and language variety (Spoken Palestinian Arabic [PA] and Modern Standard Arabic [MSA]) were analyzed for their effect on narrative retelling and comprehension. Four narratives accompanied by six pictures each (Gagarina et al., 2012) were used. Two were presented in MSA and two in PA, the children’s spoken vernacular. Two of them, one per each language variety, matched on episodic structure, were less complex, and two were more complex. Although children were free to choose which language to use for the retelling, they all used PA. Retelling performance was analyzed according to macrostructure, microstructure, and the use of Internal State Terms (ISTs). Comprehension was tested via questions addressing the character’s goals, ISTs, and Theory of Mind. With respect to text complexity, the results showed that the participants produced longer texts and demonstrated better comprehension when the narratives were more complex. Language variety was only associated with a difference in comprehension, with higher scores for the narratives presented in MSA. Older children produced longer texts and a higher number of ISTs. Finally, a three-way interaction emerged in the use of ISTs – while younger children produced more ISTs for the PA narratives, the older ones produced more of those for the MSA narratives. The study suggests that language variety and text complexity may exert different effects on narrative production and comprehension in Arabic-speaking preschool children.