Miracle-dz/UniFAR-FTUs huggingface dataset:
On regional differences in duration of sick leave : the role of work, personal and health characteristics

Objectives: The aim of this study is to explore the influence of determinants of duration of sick leave on in age and profession homogeneous groups in two different regions in the Netherlands. Apart from a statistical comparison of duration of sick leave in these regions, a literature search on determinants of duration of sick leave, spread over the last decades, was performed to get an impression of the topicality of the study. Methods: 184 participants in the regions Utrecht and South-Limburg were interviewed about work, personal and health characteristics. Data of duration of sick leave were obtained from a Dutch social fund. Later, a literature search on determinants of duration of sick leave was performed. Results: The statistical comparison of duration of sick leave in the two different regions showed that in South-Limburg determinants of 'state of health', 'motivation', 'work conditions' and 'work relations' were associated with duration of sick leave, whereas in Utrecht less predicting determinants were found, namely for 'work contents'. The literature search gives a quite consistent picture of determinants of duration of sick leave over the last decades. Conclusions: In either of the investigated regions different determinants were associated with duration of sick leave. Thus, nationwide interventions to reduce duration of sick leave are useless without taking into account the existence of regional differences in determinants that predict duration of sick leave. Determinants of duration of sick leave did not change in the last decades, therefore the results of the study are, although performed in the nineties, still relevant.
A Cephalometric Evaluation of Oropharyngeal Airway Changes Duing Twin-Block Appliance Treatment

Introduction: The research hypothesis under test was that functional orthopaedic treatment with the Twin-block appliance increases the oropharyngeal airway as well as correcting the jaw relationships in class II division 1 patients. Method: 20 cases, 10 male, 10 female. Age range: 11-18 years, average treatment time 9.4 months were randomly selected from the records of a previously completed prospective trial. Cephalometric radiographs taken before and after treatment were analysed. p, the shortest distance between the soft palate and posterior pharyngeal wall and t, the shortest distance between the tongue and the posterior pharyngeal wall were measured. Results: There was a statistically significant increase in both p and t after Twin-block appliance treatment (p=0.000). A control group selected from normative data matched individually for age and sex and treatment time showed no change over the same growth period. Conclusions: In Class II division 1 malocclusion, the oropharyngeal airway is already reduced compared to Class I and Class II. Treatment involving premolar extraction and incisor retraction further reduces the airway as does headgear and is contraindicated. Functional appliance treatment is the method of choice as it enlarges the oropharyngeal airway reducing the potential for obstructive sleep apnoea.
Weight suppression and its effects on the management of eating behaviors

Morgan, Pamela J., May, 1996 Weight Suppression and Its Effects on the Management of Eating Behaviors Director: D. Balfour Jeffrey, This investigation examined the effects ei suppression on the management of eating behaviors in a conventional restraint ice-cream taste test paradigm. All 58 female participants were restrained eaters as defined by the Three Factor Eating Questionnaire-Cognitive Restraint scale and classified as either high or low in weight suppression using the Weight Suppression Index (WSI). Weight suppressors are those persons who have successfully employed a weight-1oss diet and have kept the weight off for an extended period of time. The WSI = {(highest weight ever current weight)/ ideal weight X 100}. Under the pretense of a taste perception test, one half of subjects received a high calorie milkshake preload and the other half did not. The amount of ice-cream consumed was the measure of interest. The grams of ice-cream consumed were as follows: the high weight suppression (HWS) No Preload group (mean 97.74 gm, SD 64.01), low weight suppression (LWS) No Preload group (mean 85.33 gm, SD 58.7), the HWS Preload group (mean 79.70, SD 42.58), and the LWS Preload group (mean 78.04, SD 38.32). The 2x2 Analysis of Variance indicated no significant differences between the groups. The investigation failed to replicate many earlier restraint studies in which restrained eaters commonly consume more following a disinhibiting preload than those in the no preload condition, providing further evidence that restraint is not a homogeneous construct. It also failed to replicate a previous weight suppression study which found that high weight suppressors consumed less than low weight suppressors following a preload. Implications for further weight suppression studies are discussed. In particular, the findings question the reliability of using self-report measures for determining an individuals’ weight suppression index.
Diabetes Is an Independent Risk Factor for Cancer after Heart and/or Lung Transplantation

Background: De novo cancers are feared complications after heart or lung transplantation. Recent data suggest that diabetes mellitus (DM) might also be a risk factor for cancer. We hypothesized that transplanted diabetic patients are at greater risk of developing cancer compared to non-diabetic ones. Methods: We reviewed 353 patients post-heart and/or -lung transplantation from our center between October 1999 and June 2021. Patients with follow-up <180 days (n = 87) were excluded from the analysis. The remaining 266 patients were divided into patients who had preoperative DM (n = 88) or developed it during follow-up (n = 40) and patients without DM (n = 138). Results: The diabetic cohort showed higher rates of malignancies in all patients (30.33 vs. 15.97%, p = 0.005) and in the matched population (31.9 vs. 16.1%, p < 0.001). There were also significantly more solid tumors (17.9 vs. 9.4%, p = 0.042; matched: 16.6 vs. 9.1%, p = 0.09) The presence of diabetes was associated with a 13% increased risk of cancer when compared to non-diabetic patients. New-onset post-transplant diabetes doubled the likelihood of cancer development. Conclusions: Pre-transplant diabetes mellitus increases the risk of cancer after heart and/or lung transplantation. However, new-onset diabetes after transplantation is associated with a much greater cancer risk. This information is relevant for screening during follow-up.
Use of Human Chorionic Gonadotropin (hCG) for fixed-time artificial insemination in buffalo (Bubalus bubalis)

Abstract The aim of this study was to evaluate the efficacy of the Ovsynch protocol used for fixed-time artificial insemination in buffalo when replacing the last injection of GnRH with hCG in order to increase plasma progesterone (P4) concentrations and therefore increase conception rates. Two-hundred twelve buffaloes were randomly assigned into 2 treatment groups: G-GnRH (Day 0, GnRH; Day 7, PGF 2α ; Day 9, GnRH; n = 94) and G-hCG (Day 0, GnRH; Day 7, PGF 2α ; Day 9, hCG; n = 118). All buffaloes were inseminated on Day 10, 16 h after the last hormonal injection. On Day 22, 80 buffaloes were randomly selected for blood collections in order to measure plasma P4 concentration. Pregnancy diagnosis was performed on Day 40 by ultrasonography. Conception rates of G-GnRH and G-hCG animals were 46.8% (44/94) and 50.8% (60/118; P > 0.05), respectively. Plasma P4 concentration was lower in G-GnRH (2.94 ± 1.51 ng/ml) than in G-hCG (4.02 ± 2.34 ng/ml; P 0.05). Pregnant G-GnRH and G-hCG buffaloes had higher plasma P4 concentrations than the non-pregnant buffalo of both groups (3.54 ± 1.05 vs. 2.19 ± 1.69 ng/ml and 4.66 ± 1.73 vs. 3.18 ± 2.78 ng/ml, respectively; P < 0.05). In summary, when using the Ovsynch protocol for FTAI in buffalo, the replacement of the last GnRH administration with hCG increased the plasma P4 concentration. However, no positive effect on the conception rate was observed.
7 . Bone marrow and stem cell transplantation for multiple myeloma

Multiple myeloma is an incurable B-cell malignancy afflicting mainly elderly people with a median age of 65 to 70 years [1]. It is characterized by the proliferation of clonal plasma cells that are resistant to standard doses of commonly employed agents at the time of diagnosis, resulting in complete remission (CR) rates of only 5%-10% and median survival of approximately three years. This inherent resistance is probably due to an array of molecular abnormalities of one or more oncogenes and suppressor genes inhibiting druginduced apoptosis, including ras, myc, p53, Rb, and bcl-2, that have evolved during a prolonged subclinical course of 10-20 years [2]. The recent report of a Kaposi sarcoma-associated herpes virus (KSHV) in the dendritic cells of myeloma patients, whose genome contains the homologue to human IL-6, suggests that the KSHV may also play an important role in the etiology of multiple myeloma [3]. A combination of melphalan and prednisone has been the standard treatment for over 30 years [4]. Permutations of the melphalan/ prednisone regimen by the addition of alkylating agents and anthracychnes have not extended the median survival [5]. Dose-response evaluation had not been addressed in myeloma until the development of the VAD regimen in the early 1980s [6]. The VAD regimen, which employs continuous infusions of standard doses of vincristine and adriamycin with frequent pulses of high-dose dexamethasone, significantly increased the rapidity and degree of response by inducing apoptosis of plasma cells. However, the median survival was not significantly different from results obtained with melphalan-based regimens [7]. Increasing the dose intensity of alkylating agents, predominantly melphalan, has unequivocally resulted in more marked and rapid tumor cytoreduction, improvmg the CR incidence from approximately 5% with standard melphalan-prednisone to 20%-25% with single autotransplant and 40%-50% with tandem autotransplant [8-21]. McElwain and colleagues were the first to explore high-dose intravenous melphalan (140mg/m2) in high-risk, newly diagnosed or advanced and refractory myeloma patients without growth factor or stem cell support [22]. The marked tumor cytoreduction observed in this small trial prompted additional studies of high-dose melphalan, initially in refractory patients but more recently in newly diagnosed patients.
The role of the General Practice Liaison Nurse as integrated care coordinator: A Delphi study

In New South Wales (NSW), Australia, the position of General Practice Liaison Nurse (GPLN) was established in the early 2000s to support integrated care of patients/clients by encouraging inter professional/inter-organisational collaboration. Other terms used for this role include liaison nurse, integrated care co-ordinator, and primary care liaison nurse. The purpose of this study was to clarify the role of these nurses working in the community in outer Sydney, NSW, using a three round Delphi Technique with 19 GPLNs working in the community specialist streams of child and family, complex and chronic care, and mental health. Findings showed that the GPLN worked across 11 role domains: co-ordinator, educator, communicator, advocate, change agent, manager, collaborator, negotiator, team leader and clinician. Functions were delineated for each domain role and there were a total of 33 functions. This first study in Australia to delineate the role of the GPLN shows that while each of the domains is important, the dominant domain is co-ordination with all the other ten needed to implement this important role. The clarity of the role is important to help the nurses themselves, management, and also other stakeholders to understand their expectations of the GPLN.
Exploring the "Hidden Curriculum" in Emergency Medicine Training Programs

Introduction The Emergency Department (ED) is popular with learners. Amid the chaos we teach, sometimes oblivious to messages sent and lessons taught. This exploration of the ‘hidden curriculum’ is a glimpse at the some of the content of this curriculum in two postgraduate Emergency Medicine (EM) programs. The objective of this study was to stimulate reflection on the importance of role modeling in medical education and hopefully to moderate the content. Methods A survey and subsequent focus group interviews of faculty and residents in two Emergency Medicine (EM) training programs was conducted. The surveys were mailed in October 2005 and the focus group interviews conducted in May 2006. Results The main focus of the hidden curriculum messages were interand intra-disciplinary disrespect in the provision of care. Messages also related to patient care in the form of lack of respect, laughing at patients, and blaming them. Other elements identified included gender issues, lifestyle expectations and financial concerns. Conclusions The perceived content of the hidden curriculum was different for faculty and residents. We must heighten role-modeling consciousness
LOW-TEMPERATURE NUCLEATION OF MAGNESITE AND DOLOMITE

By way of duplicating an experiment described by L iebermann (1967) nucleation of magnesite, huntite and/or dolomite has been attaine d at temperatures between 313 K and 333 K and under atmospheric pressure. Essential to these experiments are fluctuations in pH value. After interrupting an experiment after 1, 3, 5, or 8 of such fluctuations, the change from one or more metastable phases into the stable phase (magne site or dolomite) could be followed. A theoretical explanation for these low-temperature s yntheses can be found in stability relations. Ostwald's Rule stipulates the nucleation of a metas table phase before that of the stable phase. However fluctuations of sufficient amplitude and du ration are capable of crossing the border between the metastable and the stable fields. As a re ult the stable phase will nucleate together with the metastable phase. Conditions opposing the subsequent growth of the metastable phase (such as the slightly acidic conditions resulting f rom periodically introducing CO 2 into the solution) will favour the continued growth of the s table phase. K e y w o r d s : Magnesite, dolomite, huntite, l ow-temperature syntheses.
Risk premiums and macroeconomic dynamics in a heterogeneous agent model

We analyze nancial risk premiums and real economic dynamics in a DSGE model with three types of agents shareholders, bondholders and workers that di¤er in participation in the capital market and in attitude towards risk and intertemporal substitution. Aggregate productivity and distribution risks are transferred across these agents via the bond market and via an e¢ cient labor contract. The result is a combination of volatile returns to capital and a highly cyclical consumption process for the shareholders, which are two important ingredients for generating high and countercyclical risk premiums. These risk premiums are consistent with a strong propagation mechanism through an elastic supply of labor, rigid real wages and a countercyclical labor share. Based on the empirical estimates for the two sources of real macroeconomic risk, the model generates signi cant and plausible time variation in both bond and equity risk premiums. Interestingly, the single largest jump in both the risk premium and the price of risk is observed during the current recession. JEL codes: E32, E44, G12 We would like to thank our discussants Gianni Amisano, Michel Juillard, Christos Koulovatianos and Xavier Ragot, as well as participants at the conferences on Computing in Economics and Finance (University Paris-Sorbonne), "Towards an Integrated Macro-Finance Framework for Monetary Policy Analysis" (National Bank of Belgium), "New Developments in DSGE Models" (University of Nottingham), "Theories and Methods in Macroeconomics" (BETA, Université de Strasbourg) and seminars at the Bundesbank, Erasmus University Rotterdam, European Central Bank and Ghent University. The views expressed herein are solely the responsibility of the authors and should not be interpreted as reecting the views of the Executive Board of Sveriges Riksbank, Bank of Canada, or the National Bank of Belgium. yCorresponding author: Ferre De Graeve (ferre.de.graeve@riksbank.se), Research Department, Sveriges Riksbank, SE 103 37 Stockholm, Sweden. a Sveriges Riksbank, b National Bank of Belgium, c Bank of Canada, d University of Luxembourg.
Do We Really Know that US Monetary Policy Was Destabilizing in the 1970s?

In this paper we examine whether or not monetary policy was a source of instability during the Great Inflation. We focus on a number of attributes that we see relevant for any analysis of the 1970s: cost-push or oil price shocks, positive trend inflation as well as real wage rigidity. We turn our artificial sticky-price economy into a Bayesian model and find that the U.S. economy during the 1970s is best characterized by a high degree of real wage rigidity. Oil price shocks thus created a trade-off between inflation and output-gap stabilization. Faced with this dilemma, the Federal Reserve reacted aggressively to inflation but hardly at all to the output gap, thereby inducing stability, i.e. determinacy.
University of Groningen Association of Systemic Lupus Erythematosus Clinical Features with European Population Genetic Substructure Alonso-Perez,

Systemic Lupus Erythematosus (SLE) is an autoimmune disease with a very varied spectrum of clinical manifestations that could be partly determined by genetic factors. We aimed to determine the relationship between prevalence of 11 clinical features and age of disease onset with European population genetic substructure. Data from 1413 patients of European ancestry recruited in nine countries was tested for association with genotypes of top ancestry informative markers. This analysis was done with logistic regression between phenotypes and genotypes or principal components extracted from them. We used a genetic additive model and adjusted for gender and disease duration. Three clinical features showed association with ancestry informative markers: autoantibody production defined as immunologic disorder (P = 6.8610), oral ulcers (P = 6.9610) and photosensitivity (P = 0.002). Immunologic disorder was associated with genotypes more common in Southern European ancestries, whereas the opposite trend was observed for photosensitivity. Oral ulcers were specifically more common in patients of Spanish and Portuguese self-reported ancestry. These results should be taken into account in future research and suggest new hypotheses and possible underlying mechanisms to be investigated. A first hypothesis linking photosensitivity with variation in skin pigmentation is suggested. Citation: Alonso-Perez E, Suarez-Gestal M, Calaza M, Witte T, Papasteriades C, et al. (2011) Association of Systemic Lupus Erythematosus Clinical Features with European Population Genetic Substructure. PLoS ONE 6(12): e29033. doi:10.1371/journal.pone. 0029033 Editor: Pierre Bobé, Institut Jacques Monod, France Received September 8, 2011; Accepted November 19, 2011; Published December 14, 2011 Copyright: 2011 Alonso-Perez et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Funding: This work was supported by the Instituto de Salud Carlos III (grants [06/0620, 08/0744),by the RETICS Program (RD08/0075 (RIER)) which is partially financed by the European Regional Development Fund program of the European Union, and by grants from the Xunta de Galicia and by (DFG WI 1031/6-1) awarded to TW. EA-P is the recipient of a pre-doctoral bursary of the Instituto de Salud Carlos III. MS-G is the recipient of a FPU pre-doctoral bursary of the Spanish Ministry of Education. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript. Competing Interests: The authors have declared that no competing interests exist. * E-mail: antonio.gonzalez. martinez-pedrayo@sergas.es . These authors contributed equally to this work.
Using the peabody picture vocabulary test in L2 children and adolescents: effects of L1

ABSTRACT This study investigated to what extent the Peabody Picture Vocabulary Test (PPVT-4) is a reliable tool for measuring vocabulary knowledge of English as a second language (L2), and to what extent L1 characteristics affect test outcomes. The PPVT-4 was administered to Dutch pupils in six different age groups (4-15 years old) who were or were not following an English educational programme at school. Our first finding was that the PPVT-4 was not a reliable measure for pupils who were correct on maximally 24 items, but it was reliable for pupils who performed better. Second, both primary-school and secondary-school pupils performed better on items for which the phonological similarity between the English word and its Dutch translation was higher. Third, young unexperienced L2 learners’ scores were predicted by Dutch lexical frequency, while older more experienced pupils’ scores were predicted by English frequency. These findings indicate that the PPVT may be inappropriate for use with L2 learners with limited L2 proficiency. Furthermore, comparisons of PPVT scores across learners with different L1s are confounded by effects of L1 frequency and L1-L2 similarity. The PPVT-4 is however a suitable measure to compare more proficient L2 learners who have the same L1.
Prospects and challenges of silver sulphide thin films: A review

Silver sulphide (Ag2S) has been a subject of investigation over the years for possible applications in various optoelectronics, electronics and industrial applications. Materials cost, abundance of the constituents elements, and its efficiency in use are fundamental properties in selecting materials for use as absorber or window layers in solar cell devices, or other optoelectronic applications. This paper reviews recent published work on the subject of Ag2Sbased solar cells and nano applications. The reasons for the sudden interest in the utilisation of Ag2S by the scientific community for Ag2S solar cells and other applications are discussed; coupled with the crystallographic and optoelectronic properties, including Ag2S crystalline structure, defect formation and metal composition. This review paper focuses on Ag2S synthesis processes and device properties.