Miracle-dz/UniFAR-FTUs huggingface dataset:
Mixed Endometrial Stromal and Smooth Muscle Tumor of the Uterus with Unusual Morphologic Features in a 35-Year-Old Nulliparous Woman: A Case Report

Patient: Female, 35-year-old Final Diagnosis: Mixed endometrial stromal and smooth muscle tumor Symptoms: Menorrhagia Medication:— Clinical Procedure: Mass excision Specialty: Obstetrics and Gynecology Objective: Rare disease Background: Mixed endometrial stromal and smooth muscle tumors (MESSMT) of the uterus are rare disease entities. The histogenesis is unclear, but its clinical manifestations are similar to those of other mesenchymal tumors. This unique uterine tumor was originally reported as having ultrastructural characteristics of both endometrial stromal and smooth muscle cells. Subsequently, MESSMT was defined as having at least 30% of each component present. Here we present an MESSMT with unusual features in a nulliparous woman and describe its morphological and immunohistochemical characteristics. Case Report: A 35-year-old nulliparous woman presented with menorrhagia for 2 months. Transvaginal ultrasonography and magnetic resonance imaging revealed an enlarged uterus with a 6.0×5.5×4.5 cm mass and cystic degeneration. The patient underwent abdominal mass excision. Microscopically, the tumor consisted of 3 distinct components. The outermost area consisted of smooth muscle cells. Well-differentiated endometrial stromal cells that were centrally located showed irregular borders and were merged with smooth muscle cells. In addition, the endometrial stromal component showed focal sex-cord-like differentiation. Morphological and immunohistochemical evaluations were performed, and a MESSMT with focal sex-cord-like differentiation was diagnosed. The patient’s postoperative course was uneventful for 29 months. Conclusions: The diagnosis of MESSMT is challenging due to its many overlapping features with other mesenchymal uterine tumors. Although this rare tumor was histologically and clinically consistent with low-grade endometrial stromal sarcoma, it can cause recurrence and metastasis. Therefore, regular follow-up with radiologic examination is essential for the timely detection of local recurrence and distant metastasis.
Creativity and Diversity: Challenges for quality assurance beyond 2010 'Zen, Motorcycle Maintenance, and the Metaphysics of Quality'

This paper examines the nature of the relationship between the creative, diversity-friendly and the predictability, standardisation-driven aspects of quality assurance when looked at through the lens of Robert Pirsig‟s „Metaphysics of Quality‟. In 2007, in an edition of the journal Quality Assurance in Education there was an interesting article by Laurie Lomas of Kings College London entitled: “Zen, motorcycle maintenance and quality in higher education” (a paraphrase of the title of Robert Pirsig‟s seminal 1970‟s book on the „Metaphysics of Quality‟ – “Zen and the Art of Motor Cycle Maintenance”), in which Lomas draws a distinction between the holistic „Zen‟ „transformative‟(i.e. creative, diversity-friendly approach to quality favoured by academics), and the „mechanistic‟ „narrow‟ „motorcycle maintenance‟ approach to quality typically (predictably) adopted by external quality assurance agencies. These propositions are then examined, by exploring Pirsig‟s „Metaphysics of Quality‟. This section includes consideration of various propositions about the nature of quality, from the creative and innovative, to the view of quality assurance as a maintenance manual for ensuring predictability and standardisation. The paper concludes by endorsing approaches to quality which strike a harmonious blend or balance between the creativity/diversity-friendly, and predictability/standardisation aspects.
FOSTERING CONSERVANCY THROUGH BIOPROSPECTION: THE PHARMACEUTICAL VALUE OF THE BRAZILIAN ASCIDIAN FAUNA

The inherent value of nature is immeasurable. That being said, through bioprospection – the systematic search for functional products or processes from living organisms –, the oceans and marine life have emerged as a relevant source of biodiscoveries that hold significant economic worth. Particularly considering the pharmaceutical industry, an increasing number of natural molecules of marine origin have been making their way into pipelines and receiving approval for clinical use. Still, in its earliest days, this had become an extractivist practice, putting marine environments at risk and nearly driving species to extinction through over-collecting. While it is now well understood that exploration of the oceans' living resources must withstand a sustainable agenda, thus, protecting the environment from unnatural genetic losses, it was the developments towards achieving more efficient bioprospective strategies and non-destructive but feasible means to assure product supply that pushed for the greatest advances in this field. Herein, we present our assessment of this story by telling it through the 20-year journey – and few detours –we took in the chemical and pharmacological study of the ascidian Eudistoma vannamei, a species endemic to the northeast coast of Brazil that retains novel natural products with remarkable modes of action. Indeed, ascidians figure among the most pharmacologically talented marine organisms, having yielded the active principles of three new anticancer drugs, one of which is being considered for repositioning towards the treatment of Covid-19. Finally, we argue that emphasizing the unceasing biotechnological potential of marine biological diversity, exemplified herein by Brazilian ascidians, but certainly true worldwide for this and many other groups, would work in favor of raising awareness and supporting strategies to foster conservation of the oceans. Keywords: blue biotechnology, marine biodiversity, ascidians, bioproducts, innovation.
Profiling the molecular signature of Satellite Glial Cells at the single cell level reveals high similarities between rodent and human

Peripheral sensory neurons located in dorsal root ganglia relay sensory information from the peripheral tissue to the brain. Satellite glial cells (SGC) are unique glial cells that form an envelope completely surrounding each sensory neuron soma. This organization allows for close bi-directional communication between the neuron and it surrounding glial coat. Morphological and molecular changes in SGC have been observed in multiple pathological conditions such as inflammation, chemotherapy-induced neuropathy, viral infection and nerve injuries. There is evidence that changes in SGC contribute to chronic pain by augmenting neuronal activity in various rodent pain models. SGC also play a critical role in axon regeneration. Whether findings made in rodent model systems are relevant to human physiology have not been investigated. Here we present a detailed characterization of the transcriptional profile of SGC in mouse, rat and human at the single cell level. Our findings suggest that key features of SGC in rodent models are conserved in human. Our study provides the potential to leverage rodent SGC properties and identify potential targets in humans for the treatment of nerve injuries and alleviation of painful conditions.
Wireless Magnetic Sensor Network for Road Traffic Monitoring and Vehicle Classification

Abstract Efficiency of transportation of people and goods is playing a vital role in economic growth. A key component for enabling effective planning of transportation networks is the deployment and operation of autonomous monitoring and traffic analysis tools. For that reason, such systems have been developed to register and classify road traffic usage. In this paper, we propose a novel system for road traffic monitoring and classification based on highly energy efficient wireless magnetic sensor networks. We develop novel algorithms for vehicle speed and length estimation and vehicle classification that use multiple magnetic sensors. We also demonstrate that, using such a low-cost system with simplified installation and maintenance compared to current solutions, it is possible to achieve highly accurate estimation and a high rate of positive vehicle classification.
Service Quality For Digital Wallet In Indonesia Using Sentiment Analysis And Topic Modelling

With the digital wallet, it is able to make it easy for users to store, send, and pay directly through the application. The Fintech Report by DSResearch states that Dana and ShopeePay are digital wallet products that have managed to occupy the top position in terms of daily usage frequency. However, the quality of Dana and ShopeePay services is considered less than optimal because many Dana and ShopeePay users have tweeted their complaints via Twitter social media. So that Dana and ShopeePay need to maintain service quality to maintain the loyalty of their users. This study aims to determine user sentiment towards the quality of Dana and ShopeePay services based on the e-servqual dimension and to find out what topics are formed in each e-servqual dimension to measure the service quality of Dana and ShopeePay. The data sources for this research are Dana and ShopeePay user-generated content delivered through social media Twitter. The data retrieval technique is crawling user tweets containing the keywords "@danawallet" and "@ShopeePay_ID" with a time span of 23 October 2021 to 29 December 2021. The data obtained will be classified based on the e-servqual dimension using Naive Bayes and the dataset will be analyzed using sentiment analysis and topic modeling. The results in this study show that negative sentiments dominate Dana and ShopeePay's e-servquals on the dimensions of Efficiency, System Availability, Fulfillment, and Privacy, as well as topics and words that have a negative connotation on the services provided by Dana and ShopeePay.The results of this research can be used by Dana and ShopeePay as an evaluation of service quality, especially on the e-servqual dimension to increase user satisfaction to maintain user loyalty and improve user perceptions.
The Implementation of Telepractice by Malaysian Speech-Language Pathologists During the COVID-19 Pandemic

Objectives: The Coronavirus Disease 2019 (COVID-19) led speech-language pathologists (SLPs) around the world to shift their service delivery methods from face-to-face service to telepractice. This study explored the implementation of telepractice by Malaysian SLPs and determined whether there was an association between the SLPs’ perceptions of the effectiveness of telepractice and the frequency of the telepractice services provided, as well as between the use of telepractice and prior training received.Methods: Eighty-nine SLPs responded to an 18-question online survey that inquired about demographics, telepractice during the pandemic, perceptions of telepractice and prior training received.Results: Seventy-five percent of SLPs reported providing services via telepractice during the pandemic compared to 19% before the pandemic. Most SLPs who used telepractice stated that services delivered via telepractice were comparable with face-to-face services; no association was found between the frequency of providing services via telepractice and the SLPs’ perceptions of its effectiveness. They had also received some training in telepractice, although no association was found between the type of training received and the provision of telepractice services. SLPs who did not provide services via telepractice reported awareness of telepractice but described a lack of knowledge, support, and training. All SLPs expressed interest to receive more training in telepractice to enable them to provide better services.Conclusion: Malaysian SLPs demonstrated great commitment towards service provision during the pandemic, similar to SLPs in other nations. It is hoped that Malaysian SLPs continue to have positive attitudes toward telepractice with increased familiarity, use, and training. Telepractice services, undoubtedly, are here to stay.
Learning Analytics in the Corporate Sector: What Business Leaders Say?

The widespread adoption of digital tools for learning enables extensive data collection about employee learning activities. This article analyzes how corporations use data to inform and support their learning needs. This article presents a qualitative analysis of what managers and executives overseeing learning and development initiatives in their respective organization's value in learning analytics (LA) at the workplace. The interviews were analyzed through a framework that combined lenses of value-sensitive design and value creation to uncover the values underpinning current applications of LA in the corporate sector. We found that corporations vary in their strategic LA orientations when it comes to organizational learning and development. However, although aspirational narratives of executives are diverse, their activities are not. The implications of the rich qualitative findings suggest that learning sciences can support organizational learning by creating diagnostic tools to identify organizational orientations for LA. Computer scientists can also support decision-making and research on corporate LA by creating tools that can help map organizational aspirations and activities in relation to the various data sources, stemming from different organizational units. We conclude by outlining these recommendations.
Artificial Intelligence Algorithm-Based Differential Diagnosis of Crohn's Disease and Ulcerative Colitis by CT Image

The aim of this study was to investigate the effect of low-dose CT enterography (CTE) based on modified guided image filtering (GIF) algorithm in the differential diagnosis of ulcerative colitis (UC) and Crohn's disease (CD). Methods. One hundred and twenty patients with suspected diagnosis of IBD were studied. They were randomly divided into control group (routine CT examination) and observation group (low-dose CTE examination based on improved GIF algorithm), with 60 cases in each group. Comprehensive diagnosis was used as the standard to assess the diagnostic effect. Results. (1) The peak signal-to-noise ratio (PSNR) (26.02 dB) and structural similarity (SSIM) (0.8921) of the algorithm were higher than those of GIF (17.22 dB/0.8491), weighted guided image filtering (WGIF) (23.78 dB/0.8489), and gradient domain guided image filtering (GGIF) (23.77 dB/0.7567) (P < 0.05); (2) the diagnostic sensitivity (91.49%), specificity (92.31%), accuracy (91.67%), positive predictive value (97.73%), and negative predictive value (75%) of the observation group were higher than those of the control group (P < 0.05); the sensitivity and specificity of CTE in the diagnosis of UD and CD were 96.77% and 81.25% and 98.33% and 93.33%, respectively (P < 0.05); there were significant differences in symmetrical intestinal wall thickening and smooth serosal surface between UD and CD (P < 0.05). Conclusion. (1) The improved GIF algorithm has a more effective application value in the denoising processing of low-dose CT images and can better improve the image quality; (2) the accuracy of CTE in the diagnosis of IBD is high, and CTE is of great value in the differential diagnosis of UD and CD.
Dual Electrorheological and Magnetorheological Behaviors of Poly(N-methyl aniline) Coated ZnFe2O4 Composite Particles

Magnetic/conducting polymeric hybrid core-shell typed zinc ferrite (ZnFe2O4)/poly(N-methyl aniline) (PMA) particles were fabricated and adopted as electrorheological (ER) and magnetorheological (MR) fluids, and their rheological properties were examined. Solvo-thermally synthesized ZnFe2O4 was coated with a conducting PMA through chemical oxidation polymerization. The size, shape, and chemical composition of the final core-shell shaped particles were scrutinized by scanning electron microscopy, transmission electron microscopy, and Fourier transform-infrared spectroscopy. The crystal faces of the particles before and after coating with PMA were analyzed by X-ray diffraction. The ZnFe2O4/PMA products were suspended in silicone oil to investigate the rheological response to electro- or magnetic stimuli using a rotating rheometer. The shear stresses were analyzed using the CCJ equation. The dynamic yield stress curve was suitable for the conductivity mechanism with a slope of 1.5. When magnetic fields of various intensities were applied, the flow curve was analyzed using the Hershel–Bulkley equation, and the yield stresses had a slope of 1.5. Optical microscopy further showed that the particles dispersed in insulating medium form chain structures under electric and magnetic fields. Via this core-shell fabrication process, not only spherical conducting particles were obtained but also their dual ER and MR responses were demonstrated for their wide potential applications.
Auditory experience modulates fronto-parietal theta activity serving fluid intelligence

Abstract Children who are hard of hearing are at risk for developmental language and academic delays compared with children with normal hearing. Some work suggests that high-order cognitive function, including fluid intelligence, may relate to language and academic outcomes in children with hearing loss, but findings in these studies have been mixed and to date, there have been no studies of the whole-brain neural dynamics serving fluid intelligence in the context of hearing loss. To this end, this study sought to identify the impact of hearing loss and subsequent hearing aid use on the neural dynamics serving abstract reasoning in children who are hard of hearing relative to children with normal hearing using magnetoencephalography. We found significant elevations in occipital and parietal theta activity during early stimulus evaluation in children who are hard of hearing relative to normal-hearing peers. In addition, we found that greater hearing aid use was significantly related to reduced activity throughout the fronto-parietal network. Notably, there were no differences in alpha dynamics between groups during later-stage processing nor did alpha activity correlate with hearing aid use. These cross-sectional data suggest that differences in auditory experience lead to widespread alterations in the neural dynamics serving initial stimulus processing in fluid intelligence in children.
The Effects of Colonialism toward the Timorese as depicted in Nesi’s Orang-Orang Oetimu

This research scrutinizes the effects of colonialism toward the Timorese in Oetimu as depicted in the novel of Orang-Orang Oetimu by Felix K. Nesi. From the perspective of postcolonial criticism, the combination of the invasion of the Portuguese, Japanese, and Indonesian in East Timor leaves changes in social structure and relations among the Timorese. This study aims to unveil from postcolonial view, especially Said, Gandhi, Foulcer and Day, the destructive cultural and social effect, clash of local parties, and hidden colonial power which still exists in the Timorese society. Colonialism in East Timor operated by Portuguese, Japan, and Indonesia brought about physical, social, and cultural conflicts. Portuguese colonialism impacted on the socio-political friction among Timorese and destructive vanishing of their culture. Japanese colonialism left trauma amongst them as physical oppression was often used to have domination over the people. Indonesian invasion also resulted in horizontal conflicts amongst the Timorese. Violence and corrupt culture became new perspective in solving the problems. Presenting the colonial conflicts and destructive cultural effects, the novel voices postcolonial discourse that the effect of colonialism can last long and its ideology of binary opposition and cultural justification of domination in the name of civilization can be reproduced.
The Online Betting Behavior of Sport Lottery Consumers

The sports lottery industry is growing globally, especially in the online betting market. This study focuses on online sports lottery behavior and tries to propose a framework applied in a virtual environment. Based on the Technology Acceptance Model, four antecedes (subject norm, computer anxiety, computer self-efficacy, and personal innovativeness) are added to this framework. The subjects of this study, from whom 268 valid questionnaires were collected, were betting members of sports lottery venders in the Taichung district. Findings show that subject norm is a good antecede in this framework, but computer anxiety does not reach statistical significance for explanation in this study. Both computer self-efficacy and personal innovativeness positively influence perceived usefulness. The results demonstrate the value of the expanded TAM and use of the expanded model indicates a high degree of acceptance for online betting systems among sports lottery consumers. The TAM expansion proved relevant in gathering applied information on the behavior of sports lottery consumers.
MOTIVATORS FOR USING ON-DEMAND VEHICLE SHARING SERVICES IN BRAZIL

This study focused on the analysis of motivators for the use of on-demand travel modes in Brazil. The methodological procedures included the use of combined methods of probabilistic sampling and pre-tests to design the research instrument and use of the IBM SPSS Statistics software, for data treatment which used, among others, exploratory and confirmatory factor analysis. The five major regions of Brazil were considered in this research, totaling 2150 interviews, indicating the existence of fourteen motivators for use involving the economic, social, environmental, and technological dimensions, however, only six variables comprise the structuring nucleus of demand and are based on an element of economic order (Reduced Tariff), one of a socioeconomic nature (Expectation of Benefits) and four technological drivers (Technological Availability, Convenience of Time and Boarding in addition to Data Security), which figure as utilitarian indicators, corroborating the results of international studies and contrasting those that signal hedonistic elements as relevant. In this sense, the study presents advances in establishing parameters of consumer choice based on the use of platforms aimed at displacement, figuring as an indicator of the reasons for use and their scaling of relevance in the users’ decision-making process.
The persistence of opposition in an oppressive regime: The case of the Catholic Church in Czechoslovakia

When faced with oppression from the state, some groups and individuals choose costly opposition rather than a compromise. This may be caused by the cost of compromise being higher than the cost of opposition. However, it is also possible that the persistent opposition is due to some past decisions. The paper proposes a model explaining persistent opposition as a result of group-specific investment in human capital that traps individuals in an opposition group even when she would be better off outside the group. The model is illustrated with the case of the Catholic Church in Czechoslovakia, the largest group opposing the Communist regime. Within that context, the model contributes to the explanation of the persistence and growth of the underground church under Communist rule as well as the post-Communist religious revival. The same model may also be applied to malign opposition groups, such as terrorist and criminal organizations, and it provides clues about how to deal with them.