Miracle-dz/UniFAR-FTUs huggingface dataset:
Barriers and Facilitators of Communication in the Medication Reconciliation Process during Hospital Discharge: Primary Healthcare Professionals’ Perspectives

The WHO established that medication errors are the most common and preventable errors and represent an expenditure of 42 billion U.S. dollars annually. The risk of medication errors increases in transitions between levels of care, mainly from hospital care to primary healthcare after hospital discharge. In this context, communication is a key element in the safety of the medication reconciliation process. The aim of this paper was to describe the barriers to, and facilitators of, effective communication during the medication reconciliation process at hospital discharge in people over 65 years of age, from the perspective of primary healthcare professionals. A qualitative descriptive study was designed, and in-depth interviews were conducted with 21 individuals, of whom 13 were nurses and 8 were physicians. This study was carried out with healthcare professionals belonging to primary healthcare centres in Huelva (Spain). Following content analysis of the discourses we identified 19 categories, grouped into three areas: interlevel communication, communication between primary healthcare professionals, and communication between healthcare professionals and patients/caregivers. The barriers found mainly relate to the adequacy and use of technological tools, time available, workload and the level of collaboration of patients/caregivers. Facilitating elements for communication in medication reconciliation included technologies, such as computerized medical history, protocolization of clinical sessions, the presence of case management nurse and interdisciplinary teamwork.
Inverse problems for differential operators with singular boundary conditions

Singular boundary conditions are formulated for Sturm–Liouville operators having singularities and turning points at the end‐points of the interval. For boundary‐value problems with singular boundary conditions, inverse problems of spectral analysis are studied. We give formulations of the inverse problems both for the case of separated and non‐separated singular boundary conditions. For each class of inverse problems we prove a uniqueness theorem and give a procedure for constructing the solution of the inverse problem. (© 2005 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)
L -subshell fluorescence yields and Coster-Kronig transition probabilities with a reliable uncertainty budget for selected high- and medium- Z elements

Photon-in/photon-out experiments at thin specimens have been carried out to determine $L$-subshell fluorescence yields as well as Coster-Kronig transition probabilities of Au, Pb, Mo, and Pd using radiometrically calibrated instrumentation in the Physikalisch-Technische Bundesanstalt (PTB) laboratory at the electron storage ring BESSY II in Berlin. An advanced approach was developed in order to derive the fluorescence line intensities by means of line sets of each subshell that were corrected for self-absorption and broadened with experimentally determined detector response functions. The respective photoelectric cross sections for each subshell were determined by means of transmission measurements of the same samples without any change in the experimental operating condition. All values derived were compared to those of earlier works. A completely traceable uncertainty budget is provided for the determined values.
Effect of Moringa Oleifera Leaves on Bisphenol-A Induced Histological Changes of Hepatocytes in Albino Rats

Objectives: To observe the effects of Moringa Oleifera leaves extract on BPA induced changes (Diameter of hepatocytes and vacuolization) in liver of rats. Study Design: Experimental study, conducted at Post Graduate Medical Institute. Methodology: This study was performed on 32 adult rats for seven weeks. They were divided into 4 equal groups A, B, C and D. Group A was control received corn oil only. Group B, received BPA only 50mg/kg/bw. Group C and D received BPA 50mg/kg along with MoLE 250mg and 500mg. Liver was removed and was fixed in 10% formalin. To observe the effect of BPA and MoLE, slides were prepared for histological examination. For Hepatocytes, diameter and vacuolization was observed. The statistical analysis of results was done by using SPSS 21. Result: In group B, vacuolization (87.5% of animals) and statistical significant increase in mean diameter (19.7±1.3) of hepatocytes was seen. Presence of vacuoles has presumably lead to an increase in diameter . However in Groups C 50% of animals showed vacuolization and mean mean hepatocyte diameter was 17.0±1.1. In Group D 25% of animals showed vacuolization and mean mean hepatocyte diameter decreased to14.6±1 after administration of MoLE.
Who Stays, Who Moves on and the Host Population: A Picture of Adolescents’ Perceived Well-Being and Risk Behaviours

The study aims to evaluate the health profile of first- and second-generation Romanian immigrants living in Italy compared to their adolescent peers in the country of origin (Romania) and the host population (Italian-borns). Analyses were performed on the 2013/2014 Health Behaviour in School-aged Children (HBSC) survey data. Romanian natives showed lower levels of health complaints and higher life satisfaction than Romanian migrants, who were similar to the host population, especially the second-generation ones. A comparable prevalence of being bullied was registered among Romanians, both native and immigrant, with significantly lower levels among Italian natives. Bullying others showed the second-generation migrants share a similar prevalence with the host population. The prevalence of liking school a lot was three times higher among the Romanian natives than among their peers living in Italy. Thanks to the HBSC data, this study is the first to examine the health of adolescent migrants from both the perspective of the host country and the population of origin. The results highlight the need for a more nuanced approach to studying immigrant populations, taking into account both the host country’s perspective and the health patterns of the population of origin.
Nonparametric instrument model averaging

We present a new nonparametric model averaging approach to the instrumental variable (IV) regression where the effects of multiple instruments on the endogenous variable are modelled as nonparametric functions in the reduced form equations. Even if individual IVs may have weak and nonlinear relevance to the exposure, our proposed model averaging is able to ensemble their effects with optimal weights to produce valid inference. Our analysis covers both the case in which the number of IV is fixed and the case in which the dimension of IV is diverging with sample size. This novel framework can be especially beneficial to the practical situations involving weak IVs since in many recent observational studies we may encounter a large number of instruments and their quality could range from poor to strong. Numerical studies are carried out and comparisons are made between our proposed method and a wide range of existing alternative methods.
LOCAL INTERSTELLAR MAGNETIC FIELD DETERMINED FROM THE INTERSTELLAR BOUNDARY EXPLORER RIBBON

The solar wind emanating from the Sun interacts with the local interstellar medium (LISM), forming the heliosphere. Hydrogen energetic neutral atoms (ENAs) produced by the solar-interstellar interaction carry important information about plasma properties from the boundaries of the heliosphere, and are currently being measured by NASA's Interstellar Boundary Explorer (IBEX). IBEX observations show the existence of a “ribbon” of intense ENA emission projecting a circle on the celestial sphere that is centered near the local interstellar magnetic field (ISMF) vector. Here we show that the source of the IBEX ribbon as a function of ENA energy outside the heliosphere, uniquely coupled to the draping of the ISMF around the heliopause, can be used to precisely determine the magnitude (2.93 ± 0.08 μG) and direction (227.°28 ± 0.°69, 34.°62 ± 0.°45 in ecliptic longitude and latitude) of the pristine ISMF far (∼1000 AU) from the Sun. We find that the ISMF vector is offset from the ribbon center by ∼8. °3 toward the direction of motion of the heliosphere through the LISM, and their vectors form a plane that is consistent with the direction of deflected interstellar neutral hydrogen, thought to be controlled by the ISMF. Our results yield draped ISMF properties close to that observed by Voyager 1, the only spacecraft to directly measure the ISMF close to the heliosphere, and give predictions of the pristine ISMF that Voyager 1 has yet to sample.
Multi-Scale Femtosecond-Laser Texturing for Photothermal Efficiency Enhancement on Solar Absorbers Based on TaB2 Ceramics

Tantalum boride is an ultra-refractory and ultra-hard ceramic known so far for its favorable high-temperature thermo-mechanical properties and also characterized by a low spectral emittance, making it interesting for novel high-temperature solar absorbers for Concentrating Solar Power. In this work, we investigated two types of TaB2 sintered products with different porosities, and on each of them, we realized four femtosecond laser treatments differing in the accumulated laser fluence. The treated surfaces were then characterized by SEM-EDS, roughness analysis, and optical spectrometry. We show that, depending on laser processing parameters, the multi-scale surface textures produced by femtosecond laser machining can greatly increase the solar absorptance, while the spectral emittance increase is significantly lower. These combined effects result in increased photothermal efficiency of the absorber, with interesting perspectives for the application of these ceramics in Concentrating Solar Power and Concentrating Solar Thermal. To the best of our knowledge, this is the first demonstration of successful photothermal efficiency enhancement of ultra-hard ceramics using laser machining.
Foods and Nutrients at Risk for Insufficient Intake by Community-Dwelling Healthy Older Women Eating Alone and Together in Japan—A Preliminary Finding

Eating alone and poor dental status have been reported to influence dietary intake in older adults. First, we compared nutrient and food intake and dental markers between women eating alone and together, who participated in a home health management program conducted by Kanazawa Medical University. The results showed the significantly higher intake of fresh fruit and some micro-nutrients and a lower decayed, missing, and filled teeth (DMFT) index (better dental status) in women eating alone after adjusting for age, suggesting that dental status may mediate the association between commensality and dietary intake. Then, we investigated nutrients and foods at risk for insufficient intake and associated with increasing dental markers. The risks for the insufficient intake of protein and n-3 and n-6 polyunsaturated fatty acids (PUFAs) were significantly increased with an increasing DMFT index. The risk for n-3 PUFA intake also increased with increasing numbers of missing teeth in women. Foods at risk for insufficient consumption included beans for women with an increasing DMFT index and green and yellow vegetables, fresh fruits, and meat and fish for women with increasing numbers of missing teeth. These findings suggest that good health management, including the treatment of decayed teeth, is important for the prevention of malnutrition in community-dwelling healthy older women.
Autonomous response of a third-order digital filter with two's complement arithmetic realized in parallel form

In this letter, results on the autonomous response of a third-order digital filter with two’s complement arithmetic realized as a first-order subsystem cascaded by a second-order subsystem are reported. The behavior of the second-order subsystem depends on the pole location and the initial condition of the first-order subsystem, because the transient behavior is affected by the first-order subsystem and this transient response can be viewed as an excitation of the original initial state to another state. New results on the set of necessary and sufficient conditions relating the trajectory equations, the behaviors of the symbolic sequences, and the sets of the initial conditions are derived. The effects of the pole location and the initial condition of first-order subsystem on the overall system are discussed. Some interesting differences between the autonomous response of second-order subsystem and the response due to the exponentially decaying input are reported. Some simulation results are given to illustrate the analytical results.
A mix of ginger phenols exhibits anti‑adipogenic and lipolytic effects in mature adipocytes derived from 3T3‑L1 cells

The prevalence of obesity has increased rapidly worldwide. Obesity is characterized by excessive adipose tissue in the body, which is related to hyperplasia and hypertrophy in adipocytes. Ginger (Zingiber officinale Roscoe) is a medicinal plant that possesses an anti-obesogenic effect mostly attributed to gingerols, the most abundant bioactive compounds in ginger. The anti-adipogenic and lipolytic effects of these phenols have been shown when investigated individually. Therefore, the present study aimed to evaluate the lipolytic and anti-adipogenic activity of a mix of the main ginger phenols 6-gingerol, 8-gingerol, 10-gingerol, 6-shogaol, 8-shogaol and 10-shogaol on the 3T3-L1 cell line. A total of four study groups were designed: Negative control (3T3-L1 preadipocytes); positive control (mature 3T3-L1 adipocytes); phenols-pre (3T3-L1 cells stimulated with the phenols mix during adipogenic differentiation); and phenols-post (mature 3T3-L1 adipocytes stimulated with the phenols mix). MTT viability cell assay and Oil Red O staining were performed. Glycerol concentration supernatants were determined using the VITROS 350 Chemistry System. Expression of mRNA was measured using qPCR. The treatment with a 2 µg/ml ginger phenol dose reduced the lipid content by 45.52±7.8 and 35.95±0.76% in the phenols-pre and -post group, respectively, compared with that in the positive control group. The phenols-post group presented a higher glycerol concentration in the supernatant compared with that in the positive control and the phenols-pre groups. The mRNA expression levels of CCAAT/enhancer-binding protein alpha, peroxisome proliferator activated receptor-γ, fatty acid-binding protein 4 and fatty acid synthase were higher in the phenols-pre and lower in the phenols-post groups, compared with those in the positive control group. To the best of our knowledge, the current study demonstrated for the first time the anti-adipogenic and lipolytic effects of a mix of the main bioactive compounds found in ginger, and it also established the basis to use this mix of phenols in in vivo studies and clinical trials.
The production of preverbal and postverbal subjects by Italian heritage children: Timing of acquisition matters

Heritage language (HL) speakers seem to diverge from monolingual speakers in the acquisition of syntax–discourse interface phenomena. However, most of the studies reporting this finding do not make any distinction between different types of syntax–discourse interface structures. Therefore, it is an open question whether these structures are difficult for HL speakers across the board or whether different types of structures are associated with different acquisition outcomes. In this study, we investigate whether the timing of the acquisition of syntax–discourse interface structures among monolingual children affects their acquisition by HL children. We consider the acquisition of the alternation between preverbal and postverbal subjects with unaccusative, unergative and transitive verbs in Italian. This alternation involves the syntax–discourse interface across all verb types. However, mastery of this alternation has a different timing in monolingual acquisition depending on the verb type: it emerges earlier in association with unaccusative verbs than unergative and transitive ones. We elicit narratives in Italian from 42 Italian heritage children living in Germany and ranging in age from 7 to 14 years. We focus on the analysis of preverbal and postverbal subjects, considering the effect of verb type and discourse status of the subject. The children show a good mastery of the alternation between preverbal and postverbal subjects with unaccusative verbs, whereas they exhibit difficulties with the same alternation in association with transitive and unergative verbs. Furthermore, postverbal subjects with transitive verbs are particularly vulnerable to cross-linguistic effects from German. The results of the study suggest a gradient interpretation of heritage speakers’ difficulty with syntax–discourse interface structures, with timing in monolingual acquisition being a relevant factor that modulates the degree of this difficulty. The results are not affected by children’s dominance of exposure to Italian or age.
Public Opinion About National Large-Scale Student Assessment: A Case of NAPLAN

ABSTRACT This study examines public opinion about the National Assessment Program – Literacy and Numeracy (NAPLAN) in Australia, based on an online survey conducted with a sample of New South Wales (NSW) residents (n = 2,017). Our study participants did recognize the benefits of NAPLAN despite their opinion generally trending toward negative viewpoints of the testing program. The views about the positive aspects of NAPLAN varied across socio-demographic groups, but there were more similar views concerning the negative views of NAPLAN. As predicted by the social-cultural and institutional performance models, those living in metropolitan areas and those from high SES groups tended to possess stronger positive views. Political party preference was a strong predictor of the perceptions about NAPLAN. Overall, this study offers possible explanations for the underlying mechanisms explaining sub-group differences in attitudes toward large-scale standardized national testing.
A score test for non-nested hypotheses with applications to discrete data models

This paper suggests that a convenient score test against non- nested alternatives can be constructed from the linear combination of the likelihood functions of the competing models. It is shown that this procedure is essentially a test for the correct specification of the conditional distribution of the variable of interest. As in Models for discrete data it is often necessary to fully specify the conditional distribution of the variate of interest, the test proposed here is particularly attractive in this context. The usefulness of the proposed tests is illustrated with applications to discrete choice and count data models.
Learning with random forests

This is devoted to a nonparametric estimation method called random forests, introduced by Breiman in 2001. Extensively used in a variety of areas, random forests exhibit good empirical performance and can handle massive data sets. However, the mathematical forces driving the algorithm remain largely unknown. After reviewing theoretical literature, we focus on the link between infinite forests (theoretically analyzed) and finite forests (used in practice) aiming at narrowing the gap between theory and practice. In particular, we propose a way to select the number of trees such that the errors of finite and infinite forests are similar. On the other hand, we study quantile forests, a type of algorithms close in spirit to Breiman's forests. In this context, we prove the benefit of trees aggregation: while each tree of quantile forest is not consistent, with a proper subsampling step, the forest is. Next, we show the connection between forests and some particular kernel estimates, which can be made explicit in some cases. We also establish upper bounds on the rate of convergence for these kernel estimates. Then we demonstrate two theorems on the consistency of both pruned and unpruned Breiman forests. We stress the importance of subsampling to demonstrate the consistency of the unpruned Breiman's forests. At last, we present the results of a Dreamchallenge whose goal was to predict the toxicity of several compounds for several patients based on their genetic profile.
Current and emerging technologies for defining and validating tendon cell fate

The tendon field has been flourishing in recent years with the advent of new tools and model systems. The recent ORS 2022 Tendon Section Conference brought together researchers from diverse disciplines and backgrounds, showcasing studies in biomechanics and tissue engineering to cell and developmental biology and using models from zebrafish and mouse to humans. This perspective aims to summarize progress in tendon research as it pertains to understanding and studying tendon cell fate. The successful integration of new technologies and approaches have the potential to further propel tendon research into a new renaissance of discovery. However, there are also limitations with the current methodologies that are important to consider when tackling research questions. Altogether, we will highlight recent advances and technologies and propose new avenues to explore tendon biology.
An Australia Telescope Compact Array 20-cm radio continuum study of the Large Magellanic Cloud

We present a mosaic image of the 1.4-GHz radio continuum emission from the Large Magellanic Cloud (LMC) observed with the Australia Telescope Compact Array (ATCA) and the Parkes Telescope. The mosaic covers 10. ◦ 8 × 12. ◦ 3 with an angular resolution of 40 arcsec, corresponding to a spatial scale of ∼10 pc in the LMC. The final image is suitable for studying emission on all scales between 40 arcsec and the surveyed area. In this paper, we discuss (i) the characteristics of the LMC’s diffuse and compact radio continuum emission, (ii) the fraction of the emission produced by thermal processes and the implied star formation rate in the LMC and (iii) variations in the radio spectral index across the LMC. Two non-standard reduction techniques that we used to process the ATCA visibility data may be of interest for future wide-field radio continuum surveys. The data are open to the astronomical community and should be a rich resource for studies of individual objects such as supernova remnants, H II regions and planetary nebulae as well as extended features such as the diffuse emission from synchrotron radiation.
Close-to-Nature Silviculture to Maintain a Relict Population of White Oak on Etna Volcano (Sicily, Italy): Preliminary Results of a Peculiar Case Study

Habitat loss is a potential long-term effect of projected climate change for Mediterranean forest ecosystems. Here, we investigated the effectiveness of a close-to-nature silvicultural practice to conserve an old-growth white oak forest patch in Sicily (Italy) and promote regeneration dynamics. The study area, although small, is distinctive for its isolation, position and environmental characteristics. We conducted a Before–After Control–Impact (BACI) study to analyse the responses of different taxonomic groups (vascular plants and birds) to silvicultural treatments (selection thinning, no thinning), and to determine whether close-to-nature silviculture practices may cause significant shifts in the investigated communities. Specifically, we assessed the responses of (1) vascular plants by means of species diversity and taxonomic distinctness indices and (2) birds in terms of diversity, abundance and forest specialisation. Preliminary results suggest that cautious close-to-nature silviculture practice could—by mimicking natural gap dynamics—contribute to maintaining old-growth forest patches and promote oak seedling emergence without short-term detrimental impacts on biodiversity. Although the monitoring has to be repeated over the long-term, the multi-taxon approach and indices incorporating information on taxonomic relationships into diversity measures were demonstrated to be valuable tools for interpreting biotic community structure and dynamics.