Miracle-dz/UniFAR-FTUs huggingface dataset:
POLYMORPHISM OF MTHFR C677T GENE AND THE ASSOCIATIONS WITH THE ACUTE CORONARY SYNDROME IN IRAQI PATIENTS

In Iraq, acute coronary syndrome appears to be a leading cause of morbidity and mortality. In any clinical environment, family physicians must be able to recognise and reduce risk factors as well as recognize and respond to acute coronary syndrome incidents rapidly. This study aims to investigate the genotyping of MTHFR C677T polymorphism in Iraqi patients with ACS . This study included 100 sample(50 patients with ACS and 50control group) were collection from Nasiriya heart center with aged range ( 20-50years) for period first of September 2020 and until of January 2021. Blood samples were drawn from all included samples, after that, serum was separated which then used for assess biochemical parameters Methylenetetrahydrofolate reductase (MTHFR), and 5methyltetrahydrofolate(5-MTHF) by ELISA. The result shows significantly lower in patients than control groups of serum MTHFR, and 5-MTHF levels , while The SNP rs1801133 showed TT genotype showed a significant (p=<0.01) higher frequency in patients (38%) than in control (6%) and the odds ratio for this relation was (6.714, C.I. = 1.803 24.998).
Phishpedia: A Hybrid Deep Learning Based Approach to Visually Identify Phishing Webpages

Recent years have seen the development of phishing detection and identification approaches to defend against phishing attacks. Phishing detection solutions often report binary results, i.e., phishing or not, without any explanation. In contrast, phishing identification approaches identify phishing webpages by visually comparing webpages with predefined legitimate references and report phishing along with its target brand, thereby having explainable results. However, there are technical challenges in visual analyses that limit existing solutions from being effective (with high accuracy) and efficient (with low runtime overhead), to be put to practical use. In this work, we design a hybrid deep learning system, Phishpedia, to address two prominent technical challenges in phishing identification, i.e., (i) accurate recognition of identity logos on webpage screenshots, and (ii) matching logo variants of the same brand. Phishpedia achieves both high accuracy and low runtime overhead. And very importantly, different from common approaches, Phishpedia does not require training on any phishing samples. We carry out extensive experiments using real phishing data; the results demonstrate that Phishpedia significantly outperforms baseline identification approaches (EMD, PhishZoo, and LogoSENSE) in accurately and efficiently identifying phishing pages. We also deployed Phishpedia with CertStream service and discovered 1,704 new real phishing websites within 30 days, significantly more than other solutions; moreover, 1,133 of them are not reported by any engines in VirusTotal.
University ’ s repository of research publications and other research outputs The Open University ’ s first one day symposium on treatment-emergent neuroendocrine prostate cancer Conference or Workshop Item

The Open University’s first one day symposium on treatment-emergent neuroendocrine prostate cancer attracted world-leading figures, early career researchers, and industry colleagues. The symposium proved insightful into the ‘real-world’ impact and current problems faced in the diagnosis and treatment of neuroendocrine prostate cancer. It was important for this meeting to take place as the incidence of NEPC is increasing due to the widespread use of next-generation androgen depravation drugs. The symposium discussions proposed new molecularly-driven deadlines to accelerate research and improved the treatment of this deadly and poorly recognised malignancy.
Optimal Sample Complexities for Compressed Sensing with Approximate Generative Priors

We characterize the measurement complexity of compressed sensing of signals drawn from a known prior distribution, even when the support of the prior is the entire space (rather than, say, sparse vectors). We show for Gaussian measurements and any prior distribution on the signal, that the conditional resampling estimator achieves near-optimal recovery guarantees. Moreover, this result is robust to model mismatch, as long as the distribution estimate (e.g., from an invertible generative model) is close to the true distribution in Wasserstein distance. We implement the conditional resampling estimator for deep generative priors using Langevin dynamics, and empirically ﬁnd that it produces accurate estimates with more diversity than MAP.
Electrochemical, Tribological and Biocompatible Performance of Electron Beam Modified and Coated Ti6Al4V Alloy

Vacuum cathodic arc TiN coatings with overlaying TiO2 film were deposited on polished and surface roughened by electron beam modification (EBM) Ti6Al4V alloy. The substrate microtopography consisted of long grooves formed by the liner scan of the electron beam with appropriate frequencies (500 (AR500) and 850 (AR850) Hz). EBM transformed the α + β Ti6Al4V mixed structure into a single α’-martensite phase. Тhe gradient TiN/TiO2 films deposited on mechanically polished (AR) and EBM (AR500 and AR850) alloys share the same surface chemistry and composition (almost stoichiometric TiN, anatase and rutile in different ratios) but exhibit different topographies (Sa equal to approximately 0.62, 1.73, and 1.08 μm, respectively) over areas of 50 × 50 μm. Although the nanohardness of the coatings on AR500 and AR850 alloy (approximately 10.45 and 9.02 GPa, respectively) was lower than that measured on the film deposited on AR alloy (about 13.05 GPa), the hybrid surface treatment offered improvement in critical adhesive loads, coefficient of friction, and wear-resistance of the surface. In phosphate buffer saline, all coated samples showed low corrosion potentials and passivation current densities, confirming their good corrosion protection. The coated EBM samples cultured with human osteoblast-like MG63 cells demonstrated increased cell attachment, viability, and bone mineralization activity especially for the AR500-coated alloy, compared to uncoated polished alloy. The results underline the synergetic effect between the sub-micron structure and composition of TiN/TiO2 coating and microarchitecture obtained by EBM.
Learning CIFAR-10 with a Simple Entropy Estimator Using Information Bottleneck Objectives

The Information Bottleneck (IB) principle characterizes learning and generalization in deep neural networks in terms of the change in two information theoretic quantities and leads to a regularized objective function for training neural networks. These quantities are difﬁcult to compute directly for deep neural networks. We show that it is possible to backpropagate through a simple entropy estimator to obtain an IB training method that works for modern neural network architectures. We evaluate our approach empirically on the CIFAR-10 dataset, showing that IB objectives can yield competitive performance on this dataset with a conceptually simple approach while also performing well against adversarial attacks out-of-the-box.
Learning Pareto-Optimal Policies in Low-Rank Cooperative Markov Games

We study cooperative multi-agent reinforcement learning in episodic Markov games with n agents. While the global state and action spaces typically grow exponentially in n in this setting, in this paper, we introduce a novel framework that combines function approximation and a graphical dependence structure that restricts the decision space to o ( dn ) for each agent, where d is the ambient dimensionality of the problem. We present a multi-agent value iteration algorithm that, under mild assumptions, provably recovers the set of Pareto-optimal policies, with ﬁnite-sample guarantees on the incurred regret. Furthermore, we demonstrate that our algorithm is no-regret even when there are only O (1) episodes with communication, providing a scalable and provably no-regret algorithm for multi-agent reinforcement learning with function approximation. Our work provides a tractable approach to multi-agent decision-making that is provably efﬁcient and amenable to large-scale collaborative systems.
The potential benefits of subtitles for enhancing language acquisition and literacy in children

While a considerable body of experimental work has been conducted since the beginning of the 1980s to study whether subtitles enhance the acquisition of other languages in adults, research of this type investigating subtitles as a tool for enhancing children’s language learning and literacy has received less attention. This study provides an integrative review of existing studies in this area and finds extensive evidence that subtitled AV content can indeed aid the acquisition of other languages in children and adolescents, and that it can moreover enhance the literacy skills of children learning to read in their L1 or the official language of the country in which they live and receive schooling. Recommendations for future research are also made, and it is highlighted that further research using eye tracking to measure children’s gaze behaviour could shed new light on their attention to and processing of subtitled AV content.
PRACTICES AND CHALLENGES OF CONTINUOUS ASSESSMENT IN &2//(*(6 2) 7($&+(56¶ ('8&$7,21 ,1 7+( :(67 OROMIA REGION, ETHIOPIA

The main purpose of this study was to investigate the practices and challenges of continuous assessment in colOHJHV RI WHDFKHUV¶ HGXFDWLRQ LQ WKH ZHVWHUQ 2URPLD UHJLRQ )RU WKLV VWXG\ WKH UHVHDUFKHUV VHOHFWHG WKUHH FROOHgHV WHDFKHUV¶ HGXFDWLRQ SXUSRVHO\ EDVHG RQ MRE H[SHULHQFH 7KH UHVHDUFKHUV VHOHFWHG 1HNHPWH 'HPEL 'ROOR DQG ShDPER FROOHJHV WHDFKHUV¶ HGXFDWLRQ IURP ZHOO PHGLXP ORZHU H[SHULHQFHG UHVSHFWLYHO\ 'HVFULSWLYH VXUYH\ Gesign involving both qualitative and quantitative approaches was employed. 134 student-teachers and 178 college teachers were selected and participated in the study. The quantitative data was collected through the questionnaire and observation checklist and analyzed using frequency and percentage, whereas, the qualitative data interview and document analysis were analyzed using narrative form and interpretative way. The finding of the study revealed that the extent of practicing continuous assessment in class is low. The study also showed that teachers have positive perception toward continuous assessment and they accepted continuous assessment as important to improve the achievement of learners. The finding disclosed that a large class size, shortage of time, WHDFKHUV¶ ZRUN ORDG ORZ LQWHUHVW RI VWXGHQWV ODUJH LQVWUXFWLRQDO FRQWHQW DQG ODFN RI FRPPLWPHQW DPRQJ WHDFhers as the major factors are hindering the practice of FRQWLQXRXV DVVHVVPHQW LQ FROOHJHV RI WHDFKHUV¶ HGXFation.The researchers recommend that educational authorities and stockholders should make effort to a manageDEOH QXPEHU RIVWXGHQWV¶ SHU FODVV &ROOHJH DGPLQLVWUDWRUV VKRXOG DOORZ WHDFKHUV to cover the minimum workload WKDQ RYHU ORDGLQJ DERYH WKH VWDQGDUG VHW IRU FROOHJH RI WHDFKHUV¶ HGXFDWLRQ
Modal behaviour investigation of spur gears with lumped parameter and finite element methods

Computation of gear dynamic forces accurately and correct modal behaviour estimation require highly validated modelling techniques in gear dynamics. In this paper, linear modal behaviour of a spur gear pair under prescribed conditions is investigated with lumped parameter and finite element methods. The main aim of this study is to compare the modal analysis results of the spur gear pair with the lumped parameter and finite element methods. For this purpose, a six degrees of freedom dynamic model of a spur gear pair is created using the lumped parameter method. In this method, the gears are assumed to be rigid disks whereas the gear teeth contacts and bearings are considered as flexible, which are modelled with spring elements. Then, a 3D solid model of the spur gear pair is created using the finite element method for high fidelity numerical analyses. In the finite element method, the gears are modelled with flexible three-dimensional solid elements, which is one of the main differences between the two methods. To remove the nonlinearity in the gear pair system, the contact is simplified with a rigid bonding of nodes in the finite element model. The natural frequencies and mode shapes are calculated by linear modal analysis for both methods. The obtained results from the individual methods show that flexible gear body modes, which are seen at higher frequencies, can only be detected with the finite element method. The tooth modes in which the gear bodies acting as a rigid body can be detected successfully with the two methods.
The relationship between national culture and the use of professional services THE RELATIONSHIP BETWEEN CULTURE AND THE USE OF PROFESSIONAL SERVICES: EVIDENCE FROM TWO CROSS-COUNTRY STUDIES

The relationship between culture and the use of professional services: evidence from two cross-country studies. Journal of Purchasing & Supply Management , forthcoming ABSTRACT Large sums are spent each year on professional services. However, while differences in the spending between countries can be discerned, we do not know why they occur. Inspired by the organizational buying behavior literature, this paper investigates the influence of culture on the use of professional services. As the use of professional services involves considerable uncertainties – particularly for the buyer – it can be assumed to be influenced by cultural differences regarding the level of Uncertainty Avoidance, Individualism and Masculinity. By drawing on two independent cross-country studies, we show that organizations in high uncertainty avoidance and individualistic cultures use professional services less than organizations in low uncertainty avoidance and collectivist cultures. The findings contribute to the theorizing on how the cultural context influences organizational buying behavior, and the purchasing of professional services. findings suggest that the main mechanisms explaining variations in
The influence of leadership styles and organisational politics on work engagement

The study was carried out to investigate the influence of leadership styles and perceived organisational politics on work engagement. The sample for the study consisted of 120 participants with a mean age of 36.59 years. Fifty-Eight (58) of the research participants were males while 62 were females. Participants were randomly selected from the population of civil servants at the Governor’s office in Ado Ekiti, Nigeria; using the multi-level random sampling technique. Six hypotheses were tested. Results revealed that perceived organizational politics has no significant influence on work engagement. However, perceived organizational politics influenced the dedication and vigour dimensions of work engagement. Both autocratic and democratic styles of leadership independently and jointly influenced work engagement; and there was no significant interaction effect of leadership styles and perceived organizational politics on work engagement. There was no significant main and interaction effect of sex, rank, and age of employees on work engagement. There was a significant effect of sex of leaders on the use of autocratic style of leadership while sex of leaders did not influence democratic style and perceived organizational politics. Results of present study also revealed that there was a positive relationship between leadership styles and work engagement together with its subscales. Finally, there was a significant relationship between perceived organizational politics and autocratic leadership style but not on democratic style. Findings were discussed in line with previous research findings and it was recommended that organisations should not encourage or foster political behaviours that may hamper work engagement of employees; such as preferentially treating the employees. It was also recommended that the contingency approach to leadership should be encouraged in organizations, where the situation at hand will determine the type of leadership style to use and not just get fixed to a particular leadership style. © 2014 Elixir All rights reserved. ARTICLE INF O Article h istory: Received: 27 July 2014; Received in revised form: 5 December 2014; Accepted: 16 December 2014;
Preterm delivery and low birth weight among neonates born to HIV-positive and HIV-negative Ghanaian women

1Department of Population, Family and Reproductive Health, School of Public Health, College of Health Sciences, University of Ghana, Legon, Ghana. 2Noguchi Memorial Institute for Medical Research, College of Health Sciences, University of Ghana, Legon, Ghana. 3Department of Biological Environmental and Occupational Health Sciences, School of Public Health, College of Health Sciences, University of Ghana, Legon, Ghana.
Evaluation of Propolis as Intracanal Medicament against Enterococcus faecalis

The present study aimed to comparatively evaluate Propolis, Calcium hydroxide Ca(OH)2, Chlorhexidine gel 2% (CHX) intracanal medicaments, and a mixture of Propolis with Ca(OH)2 and CHX against Enterococcus faecalis. Material and methods: One hundred and eight single-rooted extracted human teeth were used; all teeth were cut 14 mm away from the apex and prepared until size 25 master apical file. Samples were sterilized and dipped in Brain Heart Infusion Broth (BHI) contaminated with E. faecalis for 21 days at 37°C. Samples removed, divided into six groups, injected with different medicaments as following: group A: Propolis; group B: Ca(OH)2; group C: CHX; group D: Propolis + Ca(OH)2; group E: Propolis + CHX, group F: control group with no medicament, teeth sealed with filling material and nail varnish for three times periods 2, 7 and 10 days. After each time period, samples were opened and irrigated with normal saline. H-file applied to the full length to obtain dentine chips, the files collected into test tubes containing sterile BHI and stored for 48 hours under anaerobic conditions. Samples were then removed and culture in Mueller-Hinton agar, then samples incubated for one week at 37°C after which colony forming units counted using colony counter, statistical analysis was done with ANOVA and post hoc use LSD. Results: Propolis, 2% Chlorhexidine gel, and a mixture of Propolis with Calcium hydroxide were effective against E. faecalis, Calcium hydroxide, and a mixture of Propolis Chlorhexidine was not effective against it. Conclusions: Propolis showed a promising role as an intracanal medicament.
Food Enrichment with Glycyrrhiza glabra Extract Suppresses ACE2 mRNA and Protein Expression in Rats—Possible Implications for COVID-19

Angiotensin converting enzyme 2 (ACE2) is a key entry point of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus known to induce Coronavirus disease 2019 (COVID-19). We have recently outlined a concept to reduce ACE2 expression by the administration of glycyrrhizin, a component of Glycyrrhiza glabra extract, via its inhibitory activity on 11beta hydroxysteroid dehydrogenase type 2 (11betaHSD2) and resulting activation of mineralocorticoid receptor (MR). We hypothesized that in organs such as the ileum, which co-express 11betaHSD2, MR and ACE2, the expression of ACE2 would be suppressed. We studied organ tissues from an experiment originally designed to address the effects of Glycyrrhiza glabra extract on stress response. Male Sprague Dawley rats were left undisturbed or exposed to chronic mild stress for five weeks. For the last two weeks, animals continued with a placebo diet or received a diet containing extract of Glycyrrhiza glabra root at a dose of 150 mg/kg of body weight/day. Quantitative PCR measurements showed a significant decrease in gene expression of ACE2 in the small intestine of rats fed with diet containing Glycyrrhiza glabra extract. This effect was independent of the stress condition and failed to be observed in non-target tissues, namely the heart and the brain cortex. In the small intestine we also confirmed the reduction of ACE2 at the protein level. Present findings provide evidence to support the hypothesis that Glycyrrhiza glabra extract may reduce an entry point of SARS-CoV-2. Whether this phenomenon, when confirmed in additional studies, is linked to the susceptibility of cells to the virus requires further studies.
Historical evolution and future trend of Northern Hemisphere snow cover in CMIP5 and CMIP6 models

Historical snow cover over the Northern Hemisphere was examined in the satellite-based NOAA-CDR data for the period of 1970–2019. Observed annual snow cover fraction (SNF) has reduced over most areas by up to 2%/decade, while annual snow cover area (SCA) has reduced by 2 × 105 km2/decade. However, SCA in the October–December season has increased by about 5 × 105 km2/decade. CMIP5 and CMIP6 historical experiments were validated against the NOAA-CDR data. Snow cover was generally well simulated in both CMIPs, with CMIP6 models performing better. The biases in SCA reduction were larger and smaller during summer and winter, respectively. The observed increase of October–November–December SCA in the 2000s was not reproduced. Climate projections of future snow cover were evaluated in CMIP6. SNF is projected to decrease in the next 80 years, under all four scenarios evaluated (SSP126, SSP245, SSP370 and SSP585). The higher the greenhouse emissions in the shared socio-economic pathways, the faster the reduction. Under the SSP585 scenario, the rate of SCA reduction is projected to exceed −1.2 × 106 km2/decade. By 2081–2100, annual (January–March) SCA is projected to decrease by more than 30% (20%). Under the SSP126 scenario, annual (January–March) SCA is projected to only reduce by about 10% (5%) relative 1995–2014 values. The reduction of Greenhouse gas emissions is critical to controlling the loss of snow cover; future snow cover only stabilizes under the SSP126 scenario, but continue to decrease under the other three scenarios.
Determinant of users’ intention to adopt Pahang Mart on-line Portal in Malaysia: The role of perceived ease of use

Due to the various benefits offered by the information technology system, the government has taken the initiative to develop the Pahang Mart online portal system for the convenience of the people of Pahang. however if this technology is not used optimally then the government will incur losses due to the very large investments that have been made. therefore this study aims to identify the role of perceived ease of use in explaining the intention to use Pahang Mart online portal. This study was conducted in the state of Pahang with a total of 127 respondents. The sampling technique used is non-probability sampling. The findings of the study prove that perceived ease of use has a positive and significant relationship with the intention to use Pahang Mart online portal
Research on Effectiveness Assessment of Ecological Conservation in Xinjiang Based on the Cloud Model

Aiming for effective ecological conservation in Xinjiang, an effectiveness assessment system is built on the cloud model to examine the controllability of ecological conservation based on the practice in Xinjiang. It has been found that the cloud model for effectiveness assessment fully takes into account ambiguity and randomness where the expert review falls short and can effectively improve the influence of subjective factors in the assessment of ecological conservation through parameter setting and calculation. Therefore, it leads to accurate and practical assessment results. These findings can play an important referential role in improving the practicality and effectiveness of ecological conservation in Xinjiang.