Miracle-dz/UniFAR-FTUs huggingface dataset:
Management of steroid-induced hyperglycemia in hospitalized patients with cancer: a review.

PROBLEM IDENTIFICATION Glucocorticoids are prescribed for hospitalized patients with cancer for a variety of reasons, including cerebral edema, treatment and prevention of nausea, and as part of cancer treatment regimens. Glucocorticoids are known to cause hyperglycemia. The purpose of this study was to integrate the published research on the management and the effects of steroid-induced hyperglycemia in hospitalized adult patients with cancer with or without preexisting diabetes. LITERATURE SEARCH MEDLINE®, PubMed, EMBASE, CINAHL®, and Scopus electronic databases were used to identify relevant articles. Bibliographies of included studies were reviewed for any pertinent studies that were not obtained through database search.Data Evaluation: 1,392 studies were identified. A total of 18 studies that met criteria were fully reviewed, 6 of which met all of the inclusion criteria. DATA ANALYSIS Data were abstracted from the included studies using a systematic code sheet to document characteristics of the studies and findings on management of hyperglycemia. Characteristics of the studies and findings on management of hyperglycemia were organized into three tables: the patients did not have preexisting diabetes, the patients had preexisting diabetes, and patients with or without preexisting diabetes were both included in the study. Management and effects of management of hyperglycemia were then compared and synthesized.Presentation of Findings: Hyperglycemia occurs in hospitalized patients with cancer irrespective of whether patients have a prior history of diabetes. Hyperglycemia resulting from steroids is treated in a variety of ways, but the resulting glycemic control has not been consistently documented. However, this review suggests that scheduled insulin (basal-bolus) is effective in attainment of glucose targets. IMPLICATIONS FOR PRACTICE Nurses should be aware of the effect that steroids have on glycemic control in patients and should be empowered to request or perform blood glucose monitoring when appropriate. Nurses can identify those patients receiving steroids and assess for signs and symptoms of hyperglycemia. They also can review routine laboratory results and assess for hyperglycemia in patients receiving steroids.
MEASUREMENT OF ACCEPTANCE OF ONLINE ATTENDANCE SYSTEM WITH TECHNOLOGY ACCEPTANCE MODEL APPROACH: CASE IN DIRECTORATE GENERAL OF CHRISTIAN COMMUNITY, MINISTRY OF RELIGIOUS AFFAIRS OF THE REPUBLIC INDONESIA

The purpose of this study is to analyze the attitude of user acceptance of online attendance at DirectorateGeneral of Christian Community Ministry of Religious Affairs Republic of Republic of Indonesia (RI) withTechnology Acceptance Model (TAM) approach. TAM is a method for analyzing acceptance of informationsystems. The population of this study are employees who use the online presence system in their daily present.The sampling technique used is simple random sampling. Total sample used is 60 samples. The data wasprocessed using SmartPLS version 3.0 with the Structural Equation Modeling (SEM) analysis method. Theresults of the analysis of this study found that Perceived Ease of Use (PEU) had a significant effect on perceivedusefulness (PU), Perceived Ease of Use (PEU) had a significant influence on Attitudes Toward Using (ATU)and Perceived Usefulness (PU) had significant effect on Attitude Toward Using (ATU). The implication of thisresearch is that it is necessary to develop a more informative attendance system and add other features in orderto improve employee performance at Ministry of Religious Affairs RI.
Direct Discharge to Home From the Pediatric Cardiovascular ICU

OBJECTIVES: To describe direct discharge to home from the cardiovascular ICU. DESIGN: Mixed-methods including retrospective Pediatric Cardiac Critical Care Consortium and Pediatric Acute Care Cardiology Collaborative data and survey. SETTING: Tertiary pediatric heart center. PATIENTS: Patients less than 25 years old, with a cardiovascular ICU stay of greater than 24 hours and direct discharge to home from January 1, 2016, to December 8, 2020, were included. Select data describing patients discharged from acute care internally and nationally from Pediatric Acute Care Cardiology Collaborative sites were compared with the direct discharge to home cohort. INTERVENTIONS: None. MEASUREMENTS AND MAIN RESULTS: Encounter- and patient-specific characteristics. Seven-day and 30-day readmission and 30-day mortality served as surrogate safety markers. A survey of cardiovascular ICU frontline providers assessed comfort and skills related to direct discharge to home. There were 364 direct discharge to home encounters that met inclusion criteria. The majority of direct discharge to home encounters were associated with a surgery or procedure (305; 84%). There were 27 encounters (7.4%) for medical technology–dependent patients requiring direct discharge to home. Unplanned 7-day readmissions among direct discharge to home patients was 1.9% compared with 4.6% (p = 0.04) of patients discharged from acute care internally. Readmission among those discharged from acute care internally did not differ from those at Pediatric Acute Care Cardiology Collaborative sites nationally. Frontline cardiovascular ICU providers had mixed levels of confidence in technical aspects and low levels of confidence in logistics of direct discharge to home. CONCLUSIONS: Cardiovascular ICU direct discharge to home was not associated with increased unplanned readmissions compared with patients discharged from acute care and may be safe in select patients. Frontline cardiovascular ICU providers feel time constraints challenge direct discharge to home. Further research is needed to identify patient characteristics associated with safe direct discharge to home and systems needed to support this practice. Summary statistics are described using proportions or medians with interquartile ranges (IQRs) and were performed using Microsoft Excel (Microsoft, Redmond, WA). Two-sample tests of proportions were used to compare readmission frequency of the DDH cohort compared with internal and national PAC3 data using STATA Version 15 (StataCorp, College Station, TX).
Meteorological criteria for standard project hurricane and probable maximum hurricane windfields, gulf and east coasts of the United States

• • • • • • • 1. 1.1 1.2 1. 2.1 1. 2.2 1 2.3 1.3 1.4 1.5 1.5. 1 1. 5.2 1.5. 3 1.5. 4
Prostitutes, sailors and professionals - lived experiences of medical school students and staff with tattoos

Background: The aim of this study was to explore the lived experiences of medical school students and staff to uncover gaps in policy and its effects on those with tattoos. Methods: Adopting a phenomenological design, semi-structured interviews were conducted with ten medical teaching staff and students who had tattoos, within one university medical school. Five key themes emerged: tattoo motives, tattoo content, positive and negative views on tattoos and challenges for establishing policy. Results: Findings suggested that no existing stigma towards staff or students exists, however, there is an absence in existing policy regarding tattoos. Participants’ motivations for obtaining tattoos mirrored those of the public, most commonly being artistic expression. Images of tattoos related to nature were common. Views on tattoos suggested the need for a full reform of ‘dress code’ policy for the profession. Several ethically laden scenarios were espoused, highlighting the need for an official stance on tattoos. Policy discussions flagged challenges for those who construct such documents; cultural and generational differences being commonly identified by participants. Conclusions: Universally there was uncertainty on current policy, with no individual able to recount specific guidance. The existence of a hidden curriculum surrounding tattoos within medical school further increases the need for guidance reform.
Indocyanine Green (ICG) Fluorescence Is Dependent on Monomer with Planar and Twisted Structures and Inhibited by H-Aggregation

The optical properties of indocyanine green (ICG) as a near-infrared (NIR) fluorescence dye depend on the nature of the solvent medium and the dye concentration. In the ICG absorption spectra of water, at high concentrations, there were absorption maxima at 700 nm, implying H-aggregates. With ICG dilution, the main absorption peak was at 780 nm, implying monomers. However, in ethanol, the absorption maximum was 780 nm, and the shapes of the absorption spectra were identical regardless of the ICG concentration, indicating that ICG in ethanol exists only as a monomer without H-aggregates. We found that emission was due to the monomer form and decreased with H-aggregate formation. In the fluorescence spectra, the 820 nm emission band was dominant at low concentrations, whereas at high concentrations, we found that the emission peaks were converted to 880 nm, suggesting a new form via the twisted intramolecular charge transfer (TICT) process of ICG. The NIR fluorescence intensity of ICG in ethanol was approximately 12- and 9-times brighter than in water in the NIR-I and -II regions, respectively. We propose an energy diagram of ICG to describe absorptive and emissive transitions through the ICG structures such as the monomer, H-aggregated, and TICT monomer forms.
Data-driven computational modelling for some of the implications of dopamine in the brain : From subcellular signalling to area networks

Dans le cerveau, il est difficile de mettre au point des experiences avec un niveau de controle approprie a cause du haut niveau de connectivite. Pour traiter ce probleme, les modeles mathematiques sont utilises pour representer le cerveau d’une facon plus comprehensible. En effet, les modeles mathematiques peuvent etre plus pratiques que les experiences pour tester des hypotheses et chercher a extraire l’essence meme du principe etudie, en le simplifiant. De plus, la modelisation computationnelle forme une branche specifique de la modelisation mathematique, permettant de resoudre de gros calculs numeriques. Dans cette these, j’ai utilise la modelisation computationnelle a travers differentes approches pour etudier certaines regions cerebrales. Nous avons collabore avec des neurobiologistes en appliquant nos modeles a des donnees experimentales pour contribuer a mieux comprendre l’action de la dopamine, un neuromodulateur. J’ai etudie la diversite de l’action de la dopamine a trois echelles: la region cerebrale, le niveau cellulaire et le niveau moleculaire. La dopamine a un gros impact sur le cerveau et elle est principalement connue pour son implication dans le systeme de recompense. En effet, c’est une molecule associee a la prediction de recompense et de punition. Peu de regions produisent de la dopamine et ces regions sont alterees par la maladie de Parkinson ou perturbees par la depression. Pour la maladie de Parkinson, j’ai concu un modele de type taux de decharge pour reproduire l’activite neuronale des ganglions de la base. Ce modele montre des reponses neuronales significativement differentes, entre la condition temoin et la condition parkinsonienne. Par ailleurs, avec un modele de type Hodgin-Huxley prenant en compte la dynamique de l’ion potassium, j’ai pu appuyer l’hypothese que la region cerebrale appelee l’habenula, lorsqu’elle est hyperactive, induirait la depression. Cette depression serait due a un desequilibre de la concentration en potassium a cause d’une dysfonction de l’astrocyte (surexpression des canaux Kir4.1). Enfin, la dopamine est aussi impliquee dans la plasticite synaptique, un phenomene a la base de la memoire. Je l’ai etudie avec un troisieme modele, prenant en compte plusieurs resultats experimentaux relatifs a la plasticite en fonction du timing des potentiels d’action et de sa modulation.
Parkinsonism and Related Disorders

Introduction: Anxiety and mild cognitive impairment (MCI) are prevalent non-motor manifestations of Parkinson's disease (PD). While few studies have demonstrated a possible link between cognitive dysfunction and anxiety in PD, to our knowledge, no studies have directly examined the association between them. This study investigated the association between anxiety and cognitive deficits in newly diagnosed PD patients. Methods: Patients with newly diagnosed PD (N 1⁄4 185) were recruited from community and outpatient clinics. Anxiety was assessed using the Unified Parkinson's Disease Rating Scale (MDS-UPDRS) clinician rated anxiety item, which has previously been validated against a standardized criteria for the diagnosis of anxiety disorders in PD. Participants scoring 2 were classified as anxious. A threshold of 1 SD below normative values (obtained from controls) was used to define cognitive impairment. Impairments in specific cognitive domains were identified as being >1 SD below controls in 1 test per domain. Results: After controlling for age, education and motor severity, patients with anxiety were three times more likely to have cognitive impairment compared to those without anxiety (OR 1⁄4 3.0, 95% CI 1⁄4 1.2e7.3, p < 0.05). Patients with anxiety were more than twice as likely to be classified as having cognitive impairment due to impairment in the memory domain compared with PD without anxiety (OR 1⁄4 2.3, 95% CI 1⁄4 1.0e5.1, p < 0.05), whilst no associations were found between anxiety and performance on other cognitive domains. Conclusion: This study shows an association between anxiety and cognitive impairment (specifically memory impairment). Examining the neural basis of this association warrants future research in this developing field. © 2017 The Authors. Published by Elsevier Ltd. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
UvA-DARE (Digital Academic Repository) A review of solvent action on oil paint

The science of oil paint cleaning is an interdisciplinary and challenging field of study due to the complex nature of both paintings and cleaning materials. The topic requires an intimate and iterative collaboration between conservation scientists and paintings conservators. In such an interdisciplinary field, it can sometimes be difficult to interpret the practical applicability of the available literature. This review aims to bring both conservators and scientist up-to-date on the recent advances in the literature on oil paint cleaning and proposes a framework for experimental and theoretical investigations into solvent transport in oil paint. We define the physicochemical processes that occur simultaneously during cleaning as solvent action and investigate how these processes vary with the polymeric structure of the oil binding medium. The sections in this overview of the technical cleaning literature are divided into solubility, swelling and diffusion, leaching, solvent evaporation and retention and solvent-mediated chemical reactions. Models that have been used to predict varnish solubility or oil paint swelling, such as Teas chart, are critically reviewed from the perspective of the most recent developments in the various scientific disciplines involved. Technological developments in the field of modern materials for solvent-and water-based cleaning are also discussed. Finally, an outlook for the field of cleaning science is presented.
Mamíferos Xenarthra (Edentata) do Quaternario do Estado do Rio Grande do Sul, Brasil

The Xenarthra fauna of this state includes the following taxa: Dasypodidae, Dasypodinae, Propraopus sp. cf. P. grandis; Pampatheriinae, Pampatherium sp. , Holmesina sp. ; Glyptodontidae, Neothoracophorus cf. N. elevatus, Glyptodon cf. G. reticulatus, G. clavipes, Glyptodon sp. , Panochthus sp. , Doedicurus sp. ; Megalonychidae gen. et sp. ind. ; Megatheriidae, Eremotheriurn sp. ; Mylodontidae, Mylodon darwini, Glossotherium robustum, G. (Pseudolestodon) sp. and Lestodon armatus. The presence of Megatherium and Scelidotherium, although probable, needs confirmation. Despite the fauna being similar to those of the late Lujanian Age of Argentina and Uruguay, some interesting occurrences of genera from faunas with tropical affinities have been reported. These mammals and palaeoclimate data suggest a humid and cold climate (from temperate to subtropical conditions) for the late Quatemary of Rio Grande do Sul, different from the Buenos Aires Province (Argentina), where a semi-arid climate was prevalent.
A Diagnostic Study of the Velocity Structure of a Meandering Jet Using a Primitive Equation Model with Dynamic Mode Initialization

Abstract : A high resolution, 20-level, primitive equation (PE) model of the California coastal region is initialized using temperature data acquired during the first California Transition Zone (CTZ) cruise from 6 to 12 July 1988 for the purpose of diagnosing the three-dimensional dynamically balanced flow field for the region. The major feature in the region during the cruise period was a strong meandering jet which flowed equatorward and offshore, oriented in a northeast to southwest direction. The quality of data acquired during cruise CTZR1 is sufficiently high to enable diagnosis of the horizontal (baroclinic) and vertical velocity field using the numerical model. The measured (ADCP) currents showed more details of the flow at deeper depths than the model, which showed a broader baroclinic flow at depth and a level of no motion near 300 m. The maximum surface velocities from model and ADCP cross-sections agreed to within 10 cm/sec except for leg G, in which ADCP velocity was greater than the model velocity by about 30 cm/sec. The sign of vertical velocity agrees very well with independent estimates made from bio-optical data; however, the magnitude calculated by the model is 30 to 60 times larger than that estimated from the bio-optical observations.
The international law of the sea

Vol I: the law of the sea in historical prespective status of the UN Convention maritime zones - introduction internal waters and baselines the territorial sea straits used for international navigation archipelagos the contiguous zone the Continental Shelf, the exclusive economic zone and the exclusive fishing zone - the outer limit the Continental Shelf, the exclusive economic zone and the exclusive fishing zone - delimitation between neighbouring states the international legal regime of the exclusive economic zone the international legal regime of the Continental Shelf the high seas the protection and preservation of the marine environment the regime of marine scientific research the regime of seabed mining. Vol II table of cases table of statutes and other municipal instruments table of treaties United Nations Convention of the Law of the Sea, 1982 source sof the international law of the sea internal waters, territorial sea and contiguous zone straits used for international navigation archipelagos the continetnal Shelf the exclusive economic zone the high seas the protection and preservation of the marine environment the regime of marine scientific research the regime of seabed mining status of Conventions.
Prevention of intrauterine growth retardation by multiple micronutrient supplements during pregnancy in Burkina Faso

Prenatal multiple micronutrients (UNIMMAP) improve fetal growth only moderately compared to iron and folic acid alone (IFA). Whether this is due to insufficient amounts of UNIMMAP or to IFA being in reality an active control is unknown. We assessed the association between cumulative micronutrient intake (CMI) and fetal growth by secondary analysis of a randomized controlled trial in Burkina Faso where tablet intake was directly observed. We applied 2-part residual regression models adjusted for main confounders. Among the 1056 single pregnancies included, the mean CMI (6 SD) was 124 6 54 tablets. The odds of delivering a small-for-gestational-age baby was reduced by 21% [(95%CI: 5, 35); P = 0.013] for each additional tertile of CMI. The association between CMI and birth weight was positively modified by gestational age at enrollment (P-interaction = 0.001). Each unit of CMI was associated with a 1.6-g [(95%CI: 0.3, 3.1); P = 0.019] higher birth weight at a mean-centered gestational age at enrollment, with a higher gradient observed later in pregnancy. Maternal BMI at enrollment was also a positive modifying factor (P-interaction = 0.02), with no association of CMI with birth weight for low BMI. There was no evidence of an effect modification by group allocation; i.e., we observed the same change in birth weight per unit of CMI with either IFA or UNIMMAP. Yet UNIMMAP increased birth weight by 69 g [(95%CI: 58, 81); P , 0.001] relative to IFA. We found similar results for thoracic and cephalic circumferences. In conclusion, for both IFA and UNIMMAP, the effect on fetal growth is cumulative. The supplementation should therefore begin as early as possible in pregnancy, even if the growth increment per CMI is higher in late than in early pregnancy. Women with a low BMI should also receive extra energy. J. Nutr. 142: 548–554, 2012.
Dimensional stability of flakeboards as affected by board specific gravity and flake alinement

The objective was to determine the relationship between the variables specific gravity (SG) and flake alignment and the dimensional stability properties of flakeboard. Boards manufactured without a density gradient were exposed to various levels of relative humidity and a vacuum-pressure soak (VPS) treatment. Changes in moisture content (MC), thickness swelling, and linear expansion were measured and used to develop regression equations. Under board saturation conditions resulting from VPS, dimensional movement could be defined as a function of SG without regard to MC. The relationship between SG and MC was essential in defining dimensional stability changes at exposure conditions resulting in MC's below fiber saturation because equilibrium MC and equilibrium dimensional stability are independently time-related to SG and they vary with flake type and exposure conditions. Derived regression equations were used to predict thickness swelling in three-layer boards with reasonable accuracy. Reliable prediction of linear expansion depends on the analysis of many board properties. Flakeboard designed for structural applications may be constructed with several layers of flakes that vary in specific gravity (density), flake geometry, and flake alignment. Optimization of board performance is dependent on knowing the relationship between these variables and basic physical and mechanical properties. Unfortunately, most available performance data have been derived from boards of varying levels of average density which, within themselves, show a vertical density gradient. Recent publications describe the relationship between the variables of specific gravity (SG) and flake alignment and the mechanical properties of bending, tension and compression (3), and interlaminar shear, rail shear, and internal bond (4) for boards with uniform vertical density. Analysis of the dimensional stability of flakeboards is complicated by the many variables that affect this property (6,17) and the interactions occurring among these variables (21,22). Furthermore, sound conclusions based on reviews of dimensional stability literature are made difficult by the numerous exposure conditions used (7,13). Many exposures are designed primarily to determine product durability. The objective of this study was to outline the extent to which the variables SG and flake alignment affect the dimensional stability properties of thickness swelling (TS), linear expansion (LE), and the associated water adsorption at various levels of relative humidity (RH) and absorption following a vacuum-pressure soak (VPS) treatment. Evaluations were made of uniform-density boards made with several flake types, two species, and several degrees of flake alignment. Regression equations derived from the uniform density data were used to predict the properties of laboratory-made boards pressed in a conventional manner and having a normal density gradient. Materials and methods