Miracle-dz/UniFAR-FTUs huggingface dataset:
ENHANCEMENT OF ANTIBACTERIAL COMPOUNDS PRODUCTION BY ASPERGILLUS FLAVUS AND PENICILLIUM CITRINUM ISOLATED FROM LOCALS FOODS IN BOBO DIOULASSO AND OUAHIGOUYA, BURKINA FASO

In this study an effort has made to enhance the process parameters and culture conditions of isolates fungi improved production of antibacterial compound. ABSTRACT This current study was carried out to optimize media components and culture conditions for maximum antibacterial compound production and extraction by Aspergillus flavus and Penicillium citrinum . A total of five (5) isolates of Aspergillus and six (6) isolates of Penicillium were collected from groundnut and rice. Out of which one of each genera found to be promising. These isolates were identified as Aspergillus flavus and Penicillium citrinum according to respectively Raper and Fennell [1] and Pitt [2] key. The influence of culture conditions including incubation duration, incubation temperature, initial pH, agitation rate and different carbon and nitrogen sources on growth and bioactive compound production was investigated. This production was done by fermentation in synthetic broth: 5 g/l yeast extract, 1 g/l KH 2 PO4, 0.5 g/l MgSO 4 . 7 H2O, 0.01 g/l FeSO 4 . 7 H 2 O, 15 g/l NaCl, 30 g/l Glucose during one week in shaker. The disc diffusion method was used to study the antibacterial activities against two (2) Gram negative and two (2) Gram positives bacteria. The antibacterial activity was estimated on the basis of diameter of inhibition zone. Fungi showed high rate of antibacterial compound with yeast as nitrogen sources on the 7-9 days in fermentation at temperature of 30ºC and 150 rpm of the rotary shaker. The best carbon source was starch and glucose for Aspergillus flavus at pH 7 and starch and sucrose at pH 6 for Penicillium citrinum.
Trust region algorithms for optimization with nonlinear equality and inequality constraints

We consider the general nonlinear optimization problem defined as, minimize a nonlinear real-valued function of several variables, subject to a set of nonlinear equality and inequality constraints. This class of problems arise in many real life applications, for example in engineering design, chemical equilibrium, simulation and data fitting. In this research, we present algorithms that use the trust region technique to solve these problems. First, we develop an algorithm for solving the nonlinear equality constrained optimization, then we generalize the algorithm to handle the inclusion of nonlinear inequality constraints in the problem. The algorithms use the successive quadratic programming (SQP) approach and trust region technique. We define a model subproblem which minimizes a quadratic approximation of the Lagrangian subject to modified relaxed linearizations of the problem nonlinear constraints and a trust region constraint. Inequality constraints are handled by a compromise between an active set strategy and IQP subproblem solution technique. An analysis which describes the local convergence properties of our algorithms is presented. The algorithms are implemented and the model minimization is done approximately by using the dogleg approach. Numerical results are presented and compared with the results of a popular line search method. Some examples are presented in which the ability of our method to use directions of negative curvature results in greater reliability. Results of the numerical experiments indicate that our method is very robust and reasonably efficient.
PHOTOCHEMICAL AND PRODUCTIVE PERFORMANCE OF YELLOW PASSION FRUIT IRRIGATED IN THE BRAZILIAN SEMIARID

Drought stress is one of the greatest problems facing agriculture in the semiarid regions and affects immediately the physiological processes and plant production. For that, irrigation is an essential practice to minimize effects of water deficit. Its appropriate management can to increase the farm income. This study aimed to evaluate to analyze the photochemical and productive performance of passion fruit (Passiflora edulis) hybrid ‘BRS Gigante Amarelo’ irrigated in a Brazilian semiarid region. It was studied four water replacement rates (33, 66, 100 and 133% of ETo) at the field conditions. A randomized blocks experimental design it was used with five replications. The fluorescence of chlorophyll a, yield and fruit quality it were studied. The photochemical efficiency of photosystem II have been changed along the day at high temperatures. Occurred vidential damage in PHS II. Water replacement between 100 and 133% of ETo (1032 mm year-1) promotes the best production rates and quality of the fruit, but the fruit size and productivity are reduced in replacements over 100% of ETo.
Product and service reliability estimation

Some manufacturers in Europe neglect to determine the reliability of products and services, although reliability is a very significant magnitude of the quality of process results (semi-finished product, product, documentation, service). They usually declare the amount of reliability the way their competitor did, not realizing the real differences between the individual process results, which certainly causes unnecessary costs. When they declare higher reliability, then losses occur due to the high cost of customer complaints, and when they declare lower reliability, then losses arise due to large losses in demand for the results of market processes. In America, a different approach is taken to consider reliability, which involves designing, planning, and verifying the reliability of process results, using special computer programs and electronic computers. Reliability design allows defining the reliability of systems and components of process results, according to the requirements of critical quality characteristics, thereby achieving the required level of quality. Reliability planning enables the preparation of reliability checks by developing a test plan, reliability and warranty plan, a forecasting plan and a product or service guarantee plan. The reliability check makes it possible to determine the true reliability of the results of the process after experimental testing, under long-term real conditions or under short-term accelerated conditions, with the application of certain higher loads. This paper discusses the elements of stability and reliability and proposes the necessary procedure for selecting the design, planning and checking the reliability of process results. Using this selection, the procedures for designing, planning, and verifying the reliability of certain process results are shown here.
Vojta Therapy in Patients with Acute Stroke – A New Approach in Stroke Rehabilitation

Unilateral motor weakness is one of the most common deficits resulting from stroke and one of the main causes of disability. Stroke rehabilitation is multidisciplinary and the aim of physiotherapy should be to promote activation and stabilisation of the remaining innervation and functions of the damaged central nervous system. Scientific evidence demonstrating the values of specific rehabilitation interventions after stroke is limited. It is still unclear, which physiotherapeutic approaches in stroke rehabilitation are most effective. Modern approaches follow the idea that functional improvement to a large extent relies on the use of compensatory movement strategies, enabling patients to learn to cope with their deficits. The Vojta therapy is based on a completely different approach: the reflex locomotion. Vojta described inborn movement sequences of reflex locomotion that are retrievable at all times. The therapist stimulates these innate patterns of movement by applying pressure to defined zones. The therapeutic use of reflex locomotion enables elementary patterns of movement in patients with impaired locomotor system, for example due to brain damage caused by stroke, to be restored once more, assuming that repeated stimulation of these “reflex-like” movements can lead to something like “new networking” within functionally blocked neuronal networks. After Vojta treatment, these patterns are more spontaneously available to the patient. Clinical experience shows, that Vojta therapy improves postural control, uprighting against gravity and goal-directed movements. We will discuss implementation of Votja therapy in stroke rehabilitation and introduce a first ever randomized controlled trial for this approach in stroke rehabilitation.
Reliability of Evidence to Guide Decision-Making in the Use of Acupuncture for Postpartum Depression

Background There is conflicting evidence on the effectiveness of acupuncture in the treatment of postpartum depression (PPD). This study aimed to assess previous systematic reviews/meta-analyses (SRs/MAs) on the effectiveness of acupuncture to treat PPD. Method SRs/MAs regarding the use of acupuncture for PPD were identified from the establishment of digital databases to November 2021. The Assessing the Methodological Quality of Systematic Reviews 2 (AMSTAR-2) was applied to evaluate the methodological quality of included SRs/MAs. The Grades of Recommendations, Assessment, Development and Evaluation (GRADE) was utilized to evaluate the evidence quality for outcomes of interest. Results Six studies that conducted quantitative syntheses were included. According to AMSTAR-2, the methodological quality of these SRs/MAs was critically low owing to limitations of items 2, 4, and 7. According to GRADE, no study included high-quality evidence and most studies included low-quality evidence. Conclusions Acupuncture m be beneficial for PPD, however, due to limitations of current evidence and inconsistent findings, further studies are needed to provide stronger evidence to draw definitive conclusions.
Child Homicide Amounting to Murder in Malaysia: Descriptive Analysis of the Statistics and Causes

Objective To describe the child homicide rates and examine the circumstances of homicides of children in Malaysia from January 2010 to June 2021. Methods This is a retrospective secondary analysis of police records on child homicides in Malaysia. Background demographic characteristics of victims, suspected offenders, motives of homicide, and rates of child homicide in Malaysia were analyzed descriptively. Results Three hundred thirty-two child homicide cases involving 349 children aged 18 years old and below by 458 suspected offenders were described. The Malaysian rates of child homicide from 2010 to 2018 fluctuated between 0.28 and 0.37 per 100,000 population of children aged 18 and below. The rates show decreasing trend to 0.19 and 0.17 per 100,000 population of children aged 18 in 2019 and 2020, respectively. Most of the victims were Malay and Indians, boys, aged 0–5 years old and 16–18 years old. Offenders were likely to be someone known to the victims, including parents, stepparents, and friends, and have unstable incomes. The main possible motives of homicide are jealousy and revenge, child abuse, and feeling distress. Conclusion The rates of child homicide in Malaysia are lower compared to other countries and show decreasing trend during this COVID-19 pandemic. These findings perhaps are underestimated and should be cautiously interpreted. Nevertheless, the results should inform immediate intervention to target the at-risk groups.
Unrevealing the Hidden Effects of Job Insecurity: A Moderated-Mediation Model of Moral Disengagement and Moral Identity

Moral disengagement is an intensely negative reaction that triggers unethical behavior in the workplace. By integrating the conservation of resources and moral disengagement theories, the current research examined how moral disengagement can explain the mechanism through which job insecurity results in adverse consequences. Furthermore, moral identity was theorized to moderate the hypothesized relationships. The theoretical model was tested by using time-lagged multisource data collected from 425 Chinese employees and their respective supervisors associated with the healthcare sector. The study concluded that job insecurity was positively linked with employees’ moral disengagement, which, in turn, led to coworker undermining behavior. Furthermore, moral identity moderated the relationship between job insecurity, moral disengagement, and coworker undermining such that employees high in moral identity experience less moral disengagement and are less involved in coworker undermining. Theoretical and practical implications along with future research avenues are discussed.
An Investigation Into the Interplay Between Chinese EFL Teachers' Emotional Intelligence, Ambiguity Tolerance, and Work Engagement

Teachers' work engagement is regarded as a critical issue in educational contexts, so the emotional factors and personality traits, and their effects on teacher engagement have drawn the attention of investigators. This study seeks to investigate the relationship between teachers' emotional intelligence, ambiguity tolerance, and work engagement. Moreover, this study tries to investigate the contribution of emotional intelligence and ambiguity tolerance to teachers' work engagement. To do so, 322 teachers (96 males and 226 females) participated in this study. Schutte's Self Report Emotional Intelligence Test (SSEIT), Multiple Stimulus Types Ambiguity Tolerance Scale-II (MSTAT-II), and Self-report engagement Questionnaire were used in this study. The statistical techniques used in this study are the Spearman Rho test and ANOVA. The findings showed that there are significant correlations between work engagement, emotional intelligence, and ambiguity tolerance. Comparing the predictability power, teachers' emotional intelligence (B = 0.611) proved to have a higher index compared to their index of ambiguity tolerance (B = 0.2). This study concluded that emotionally intelligent teachers and teachers with higher levels of ambiguity tolerance are more engaged in the EFL contexts. Moreover, the study has some pedagogical implications and suggestions for different teacher educators, policy-makers, and advisors. The ideas can improve their awareness of teachers' emotional intelligence, ambiguity tolerance, and work engagement in educational environments.
Epidemiological Trends in Alopecia Areata at the Global, Regional, and National Levels

Background No comprehensive studies have been published on the global burden of alopecia areata since 2010. Objective We aimed to measure the global, regional, and national incidence of alopecia areata and disability-adjusted life-years (DALYs) by age, sex, and socio-demographic index (SDI) value from 1990 to 2019. Methods Data were extracted from the Global Burden of Disease Study 2019. Estimated annual percentage changes (EAPCs) were calculated to quantify temporal trends in the age-standardized rates of alopecia areata incidence and DALYs. The correlations between EAPCs in the age-standardized rates and SDI values were also analyzed. Results From 1990 to 2019, the alopecia areata incidence number and the associated number of DALYs increased globally by 49.14%, and 49.51%, respectively. The global age-standardized incidence rate decreased (EAPC, −0.13; 95% confidence interval [CI], −0.13 to −0.12) and the age-standardized DALY rate showed a downward trend (EAPC, −0.12; 95% CI, −0.13 to −0.11). The largest increases in the age-standardized incidence rate and age-standardized DALY rate were observed in Low SDI quintile and Western Sub-Saharan Africa regions. The regions with the greatest changes in the incidence of alopecia areata were Central Sub-Saharan Africa and Western Sub-Saharan Africa. The three countries with the largest increases in alopecia areata incidence from 1990 to 2019 were Kuwait (EAPC, 0.15), South Sudan (EAPC, 0.12), and Nigeria (EAPC, 0.11). The age-standardized incidence rate was higher in females than in males. Conclusion Globally, both the age-standardized incidence rate and age-standardized DALY rate of alopecia areata showed decreasing trends. Future preventive strategies should focus on low-income countries, Central Sub-Saharan Africa, Western Sub-Saharan Africa, Kuwait, South Sudan, Nigeria.
Neuromodulation Strategies to Reduce Inflammation and Improve Lung Complications in COVID-19 Patients

Since the outbreak of the COVID-19 pandemic, races across academia and industry have been initiated to identify and develop disease modifying or preventative therapeutic strategies has been initiated. The primary focus has been on pharmacological treatment of the immune and respiratory system and the development of a vaccine. The hyperinflammatory state (“cytokine storm”) observed in many cases of COVID-19 indicates a prognostically negative disease progression that may lead to respiratory distress, multiple organ failure, shock, and death. Many critically ill patients continue to be at risk for significant, long-lasting morbidity or mortality. The human immune and respiratory systems are heavily regulated by the central nervous system, and intervention in the signaling of these neural pathways may permit targeted therapeutic control of excessive inflammation and pulmonary bronchoconstriction. Several technologies, both invasive and non-invasive, are available and approved for clinical use, but have not been extensively studied in treatment of the cytokine storm in COVID-19 patients. This manuscript provides an overview of the role of the nervous system in inflammation and respiration, the current understanding of neuromodulatory techniques from preclinical and clinical studies and provides a rationale for testing non-invasive neuromodulation to modulate acute systemic inflammation and respiratory dysfunction caused by SARS-CoV-2 and potentially other pathogens. The authors of this manuscript have co-founded the International Consortium on Neuromodulation for COVID-19 to advocate for and support studies of these technologies in the current coronavirus pandemic.
The Role of Working Memory, Short-Term Memory, Speed of Processing, Education, and Locality in Verb-Related Morphosyntactic Production: Evidence From Greek

This study investigates the relationship between verb-related morphosyntactic production (VRMP) and locality (i.e., critical cue being adjacent to the target or not), verbal Working Memory (vWM), nonverbal/visuospatial WM (nvWM), verbal short-term memory (vSTM), nonverbal/visuospatial STM (nvSTM), speed of processing, and education. Eighty healthy middle-aged and older Greek-speaking participants were administered a sentence completion task tapping into production of subject–verb Agreement, Time Reference/Tense, and grammatical Aspect in local and nonlocal configurations, and cognitive tasks tapping into vSTM, nvSTM, vWM, nvWM, and speed of processing. Aspect elicited worse performance than Time Reference and Agreement, and Time Reference elicited worse performance than Agreement. There were main effects of vSTM, vWM, education, and locality: the greater the participants’ vSTM/vWM capacity, and the higher their educational level, the better their VRMP; nonlocal configurations elicited worse performance on VRMP than local configurations. Moreover, vWM affected Aspect and Time Reference/Tense more than Agreement, and education affected VRMP more in local than in nonlocal configurations. Lastly, locality affected Agreement and Aspect (with nonlocal configurations eliciting more agreement and aspect errors than local configurations) but not Time Reference. That vSTM/vWM (but not nvSTM/nvWM) were found to subserve VRMP suggests that VRMP is predominantly supported by domain-specific, not by domain-general, memory resources. The main effects of vWM and vSTM suggest that both the processing and storage components of WM are relevant to VRMP. That vWM (but not vSTM) interacts with production of Aspect, Time Reference, and Agreement suggests that Aspect and Time Reference are computationally more demanding than Agreement. These findings are consistent with earlier findings that, in individuals with aphasia, vWM interacts with production of Aspect, Time Reference, and Agreement. The differential effect of education on VRMP in local vs. nonlocal configurations could be accounted for by assuming that education is a proxy for an assumed procedural memory system that is sensitive to frequency patterns in language and better supports VRMP in more frequent than in less frequent configurations. In the same vein, the interaction between locality and the three morphosyntactic categories might reflect the statistical distribution of local vs. nonlocal Aspect, Agreement, and Time Reference/Tense in Greek.
Temporal Dynamics in Energy Fluxes and Trophic Structure of a Portunus trituberculatus Polyculture Ecosystem During Different Culture Periods

Swimming crab (Portunus trituberculatus) are an important aquaculture species in eastern coastal areas of China. To improve the understanding of P. trituberculatus culture ecosystem functioning, the dynamics of energy flow and trophic structure of a P. trituberculatus polyculture system (co-culture with white shrimp Litopenaeus vannamei and short-necked clam Ruditapes philippinarum) were investigated in this study. Three Ecopath models representing the early, middle, and late culture periods of a P. trituberculatus polyculture ecosystem, respectively, were constructed to compare ecosystem traits at different culture periods. The results demonstrated that detritus was the main energy source in this polyculture ecosystem, and most of the total system throughput occurred at trophic levels I and II. Artificial food input and consumption by the culture organisms increased from early to middle and late periods, which produced marked impacts on biomass structure and primary production. R. philippinarum was considered to have a dominant influence on phytoplankton community dynamics which changed from nano- to pico-phytoplankton predominance, from the middle to the late period. Considering the low utilization efficiency of pico-phytoplankton production, large amounts of detritus accumulated in the sediment in the late period, which may constitute a potential risk for the ecosystem. Ecological network analyses indicated that the total energy flow and level of system organization increased from the early to the middle and late periods, whereas food web complexity and system resilience decreased from early to middle and late periods, which may indicate a trend of decreasing ecosystem stability. The system may be further optimized by increased stocking density of R. philippinarum and by introducing macro-algae at a suitable biomass to increase ecosystem stability, energy utilization efficiency, and aquaculture production.