Miracle-dz/UniFAR-FTUs huggingface dataset:
Human Monocytes 5/RANTES and by Lipopolysaccharide in Activated by the CC Chemokine Ligand Analysis of the Gene Expression Profile

The gene expression proﬁle induced by the CC chemokine ligand (CCL) 5/RANTES in human monocytes was examined using the oligonucleotide array technology. Of 5600 transcripts examined, 42 were consistently induced by CCL5, and none were sup-pressed. Chemokine-inducible transcripts could be clustered in functional groups, including selected cytokines and receptors (e.g., IL-1 (cid:1) , CCL2/monocyte chemotactic protein-1, and the CCL5 receptor CCR1) and molecules involved in extracellular matrix recognition and digestion (e.g., CD44 splice transcripts, urokinase-type plasminogen activator receptor, matrix metalloprotease (MMP)-9 , and MMP-19). Transcript expression, conﬁrmed by quantitative real-time PCR analysis for selected genes, was associated with protein induction for some (e.g., CCL2), but not all (e.g., IL-1 (cid:1) ), transcripts examined. The chemokine-induced gene proﬁle was distinct from that activated by LPS, a prototypic phagocyte activator. Although certain transcripts were stimulated by both agonists (e.g., IL-1 (cid:1) and CCL2), others were induced only by either LPS (e.g., TNF- (cid:2) and IL-6) or CCL5 (e.g., MMP-19) or were divergently regulated (e.g., CCR1). Thus, CCL5, a prototypic CC inﬂammatory chemokine, activates a restricted transcriptional program in monocytes distinct from
Role of Complex Carbohydrates in Human Immunodeﬁciency Virus Type 1 Infection and Resistance to Antibody Neutralization (cid:1)

Complex N - glycans ﬂank the receptor binding sites of the outer domain of HIV-1 gp120, ostensibly forming a protective “fence” against antibodies. Here, we investigated the effects of rebuilding this fence with smaller glycoforms by expressing HIV-1 pseudovirions from a primary isolate in a human cell line lacking N acetylglucosamine transferase I (GnTI), the enzyme that initiates the conversion of oligomannose N - glycans into complex N - glycans. Thus, complex glycans, including those that surround the receptor binding sites, are replaced by fully trimmed oligomannose stumps. Conversely, the untrimmed oligomannoses of the silent domain of gp120 are likely to remain unchanged. For comparison, we produced a mutant virus lacking a complex N - glycan of the V3 loop (N301Q). Both variants exhibited increased sensitivities to V3 loop-speciﬁc monoclonal antibodies (MAbs) and soluble CD4. The N301Q largely correspond to the structures in reference 78. We considered the possibility of constructing V3-containing trimer models to illustrate the large complex glycan at residue N301 and the possible effects of its replacement or removal. A major caveat, however, is that the only V3 loop-containing gp120 structure presently available is in a complex with sCD4 and X5 (47). Docking this structure into the unliganded density of the trimer produces a trimer model with a highly exposed V3 loop (see Fig. 2F in reference 69), but that cannot be the case on unliganded primary isolates, because V3 antibodies do not tend to neutralize those isolates (11).
E ﬀ ect of Logarithmically Transformed IMERG Precipitation Observations in WRF 4D-Var Data Assimilation System

: Precipitation estimates from numerical weather prediction (NWP) models are uncertain. The uncertainties can be reduced by integrating precipitation observations into NWP models. This study assimilates Version 04 Integrated Multi-satellite Retrievals for the Global Precipitation Measurement (GPM) (IMERG) Final Run into the Weather Research and Forecasting (WRF) model data assimilation (WRFDA) system using a four-dimensional variational (4D-Var) method. Three synoptic-scale convective precipitation events over the central United States during 2015–2017 are used as case studies. To investigate the e ﬀ ect of logarithmically transformed IMERG precipitation in the WRFDA system, this study reports on several experiments with six-hour and hourly assimilation windows, regular (nontransformed) and logarithmically transformed observations, and a constant observation error in regular and logarithmic spaces. Results show that hourly assimilation windows improve precipitation simulations signiﬁcantly compared to six-hour windows. Logarithmically transformed precipitation does not improve precipitation estimations relative to nontransformed precipitation. However, better predictions of heavy precipitation can be achieved with a constant error in the logarithmic space (corresponding to a linearly increasing error in the regular space), which modiﬁes the threshold of rejecting observations, and thus utilizes more observations. This study provides a cost function with logarithmically transformed observations for the 4D-Var method in the WRFDA system for future investigations.
Isolation and Characterization of Campylobacter spp. from Antarctic Fur Seals ( Arctocephalus gazella ) at Deception Island, Antarctica (cid:1)

The presence of Campylobacter spp. was investigated in 41 Antarctic fur seals ( Arctocephalus gazella ) and 9 Weddell seals ( Leptonychotes weddellii ) at Deception Island, Antarctica. Infections were encountered in six Antarctic fur seals. The isolates, the ﬁrst reported from marine mammals in the Antarctic region, were identiﬁed as Campylobacter insulaenigrae and Campylobacter lari . The Antarctic and sub-Antarctic regions are often regarded as pristine landscapes, unaffected by human activity. A limited number of surveys have been carried out to investigate the possible occurrence of zoonotic enteropathogens and if certain bacteria could be used as tools for evaluating biological pollution in this area (4, 11). In the case of Campylobacter species, there have been only
OCCURRENCE OF TOXOPLASMA ANTIBODIES IN CAPRINE MILK AND SERUM IN EGYPT

___________________________________________________________________________ (cid:1)(cid:2)(cid:3)(cid:4)(cid:5) (cid:6)(cid:7)(cid:8)(cid:2)(cid:9)(cid:3) (cid:10)(cid:1)(cid:7)(cid:11)(cid:12)(cid:13)(cid:3) (cid:7)(cid:12)(cid:14)(cid:15)(cid:16)(cid:4)(cid:8)(cid:17)(cid:4)(cid:5)(cid:18)(cid:13) (cid:19)(cid:20) (cid:21)(cid:16)(cid:13) (cid:6)(cid:1)(cid:4) (cid:14)(cid:22)(cid:7)(cid:12)(cid:13)(cid:3) (cid:23)(cid:24)(cid:12)(cid:16) Toxoplasma specific antibodies were identified in both serum and milk of naturally infected goats using Indirect Hemagglutination Test (IHAT). Samples were collected from a total of 182 goats in different localities of Greater Cairo, Beni-Suif, and Zagazig regions, where both milk and serum samples were obtained from 73 lactating and only serum samples from109 non-lactating goats. Milk was investigated for the presence of T. gondii using experimentally infected cats. The results indicated that 77(42.30 %) out of 182 were seropositive, where 38 (34.86%) out of 109 non-lactating goats were seropositive for T.gondii antibodies using IHAT. Positive results were also indicated in 43(58.90 %), and 39(53.42 %) out of 73 lactating does in both milk and serum samples. Toxoplasma IgG and IgM antibodies were detected in 55(30.22%) and 22(12.09%) out of 77 samples respectively. All experimentally infected cats fed on milk from acutely infected goats shed T.gondii oocysts, whereas only one out of 4 cats fed on milk from chronically infected goats shed T.gondii oocysts in their faeces. The public health importance due to consumption of raw or unpasteurized goat milk was discussed.
ICASH-A056 IS THE MULTIPLE MICRONUTRIENTS BETTER TO REDUCE ANEMIA IN PREGNANCY COMPARED TO IRON- FOLATE ACID SUPLEMENTATION? A SYSTEMATIC REVIEW

Background : Prevalence of anemia continues to increase among pregnant women in Indonesia. The micronutrients that are needed to reduce the anemia is still lacking to be accessed by pregnant women. This study aims to analyze the effectiveness of multiple micronutrients (MMN) compared to the iron-folic acid to reduce the incidence of anemia among pregnant women. Methods : Systematic review was used in this study using the electronic databases Google Scholar, Science Direct, and PubMed. The articles included in this study were published in 2009-2018 and were written in English language. Results: In total, 380 papers were identified and six articles were included in this study. Study found that the MMN and iron-folic acid had the same effect in influencing the anemia status among pregnant women. However, the MMN had a potential to increase the average of body weight, to reduce the incidence of low birth weight (LBW) and preterm birth among pregnant women. Conclusions: The effectiveness of multi micronutrients in pregnant women is as good as iron-folic acid in reducing the anemia during pregnancy. Further studies need to be conducted to see the effects of MMN on pregnant women by considering other factors such as maternal nutritional status, gestational age, and duration of supplementation . to research conducted in Bangladesh with the title "Effect of prenatal micronutrient and early food supplementation on maternal hemoglobin, Birth Weight, and Infant mortality among children in Bangladesh", with a total sample of 4436 pregnant women. This study included inclusion criteria, namely the population living in villages in Bangladesh who received health services from the International Center for Diarrheal Disease Research, Bangladesh (ICDDR, B), pregnant women with less than 14 weeks' gestation who were examined using USG, did not have severe illness, and willing to be a sample in the study. The purpose of this study was to see whether prenatal multi micronutrient supplementation (MMS) and food supplementation would increase maternal hemoglobin, infant birth weight and reduce infant mortality rate. The sample group in this study was divided into 2 large groups, namely in the first group the administration of supplementation was carried out at 9 weeks gestation while the second group was given supplementation at 20 weeks' gestation. In each group 3 types of supplementation were given, namely 30 mg iron + 0.4 folic acid, 60 mg iron + 0.4 folic acid, and 15 micronutrients + 30 mg iron + 0.4 mg folic acid with daily doses combined with food supplement (608 kcal, 6 days a week). The intervention is given until 30 weeks' gestation. The researchers compared maternal hemoglobin levels, infant weight at birth and infant mortality in 6 groups. Measurements are taken at 30 weeks' gestation. The results of the study based on maternal hemoglobin levels were no difference in mean hemoglobin levels in the group given micronutrients [12]. Relative researchers compared study
Eff ect of Celecoxib in addition to standard therapy in adults with Major Depressive Disorder: A double-blind, randomized clinical trial P rinciples and Practice of Clinical Research: Study Design

Introduction: Major depressive disorder (MDD) is an important cause of disability and only about 50% of patients achieve remission with standard antidepressant treatment. There is evidence that inflammatory mechanisms mediate the development and progression of this disease. However, controversy remains about the use of anti-inflammatory drugs as a therapeutic option for MDD. Research Hypothesis: Patients with MDD who receive celecoxib plus standard therapy achieve a lower score in the Hamilton rating scale for depression (HRSD) when compared to placebo plus standard therapy. Methods: A total of 80 out-patients from the Mental Health Service of the Fundacion Santa Fe de Bogotá, aged 20-40 years old, with a diagnosis of moderate or severe MDD without previous treatment in the last 6 months will be included. Patients will be randomized to Celecoxib or placebo with an allocation ratio of 1:1 using a web-based random number generator. The primary endpoint will be the difference between the pretest and posttest score of the HRSD, after 6 months of treatment. Feasibility: This trial is feasible and relevant to the theme, in spite of the difficulty to maintain adherence in a study with MDD. Anticipated Results: Decrease in HRSD is expected in both groups during follow-up, but it is expected to be larger in the celecoxib group. A more rapid decrease of HRSD scores is expected in the 1 st weeks.
Longwave and bi-color type-II InAs/(In)GaSb superlattice infrared detectors

OF DISSERTATION Submitted in Partial Fulfillment of the Requirements for the Degree of Doctor of Philosophy Optical Sciences and Engineering The University of New Mexico Albuquerque, New Mexico May, 2010 Longwave and Bi-color Type-II InAs/(In)GaSb Superlattice Infrared Detectors by Arezou Khoshakhlagh B.S., University of New Mexico, 2004 M.S., University of New Mexico, 2008 Ph.D., Optical Sciences and Engineering, University of New Mexico, 2010 Abstract Infrared (IR) photodetectors are useful for a variety of military and civil applications such as target acquisition, medical diagnostics, pollution monitoring, to name just a few. Presently photonic IR detectors are based on interband transitions in low bandgap semiconductors such as mercury cadmium telluride (MCT) or InSb or in intersubband transitions in hetero-engineered structures such as quantum well or quantum dot infrared photodetectors (QWIPs or QDIPs). These detectors operate at low temperatures (77 K-200 K) in order to obtain high signal to noise ratio. The cooling requirement limits the lifetime, increases the weight and the total cost, as well as the power budget, of the whole infrared system. There is a concerted effort to develop photonic detectors operating at higher temperatures. In the past few years, interband transitions in type II InAs/GaSb strain layer superlattices (SL)Infrared (IR) photodetectors are useful for a variety of military and civil applications such as target acquisition, medical diagnostics, pollution monitoring, to name just a few. Presently photonic IR detectors are based on interband transitions in low bandgap semiconductors such as mercury cadmium telluride (MCT) or InSb or in intersubband transitions in hetero-engineered structures such as quantum well or quantum dot infrared photodetectors (QWIPs or QDIPs). These detectors operate at low temperatures (77 K-200 K) in order to obtain high signal to noise ratio. The cooling requirement limits the lifetime, increases the weight and the total cost, as well as the power budget, of the whole infrared system. There is a concerted effort to develop photonic detectors operating at higher temperatures. In the past few years, interband transitions in type II InAs/GaSb strain layer superlattices (SL)
Third Generation Disadvantage among Mexican

Among Mexican Americans, generational differences in education do not fit with assimilation theory’s predictions of significant improvement from the second to third generation; instead, education for third generation remains similar to the second generation and falls behind that of non-Hispanic whites. Scholars have not examined this educational gap for recent cohorts, nor have they considered a wide range of economic outcomes by generation. Using a nationally representative sample of young adults from the National Educational Longitudinal Survey, we examine various educational and economic outcomes among second- and third-generation Mexican Americans and compare it to whites and blacks. We find that third-generation Mexican Americans have similar outcomes to the second generation and lower education and economic levels than whites and blacks, even when controlling for key factors. Our findings reveal limitations to assimilation theory and suggest that the persistent low status of third-generation Mexican Americans may be largely due to their racialization. These findings coupled with prior research on Mexican Americans point to a consistent pattern of third generation disadvantage, which stands in contrast to second generation advantage.
Results and Predictive Factors for Sur vival of Periampullar y Cancer Patients at Uttaradit Hospital The THAI Journal of SURGERY

Introduction: Periampullary cancer is one of the major health concerns worldwide. Even though there are some attempts to work the disease out, the prognosis of periampullary cancer remains poor. Objective: To study results and predictive factors for survival of periampullary cancer patients at Uttaradit Hospital. Patients and Methods: A long-term observational analytic study was done. Information of 82 patients diagnosed with periampullary cancer who received treatment at Uttaradit Hospital from October 2007 to October 2012 was gathered from the database of Department of Surgery, Uttaradit Hospital. The patients’ final status had been followed until September 2015. Descriptive statistics, Kaplan-Meier method and a Log-rank test were applied to analyze the information. Results: Patients had an average age of 64.99 years and 52.44% of them were male. All patients had primary tumors located in places as follows: 56.09% at the head of pancreas and 39.02% at the ampulla of Vater. Pancreaticoduodenectomy (PD) was performed in 48.78% of the patients. The overall mortality rate was 53.66%. The median survival time was 2.75 years. The predictive factors were chronic alcohol drinking ( p < 0.01) and PD operation ( p < 0.05). Conclusion: Chronic alcohol drinking and a PD operation have significant contribution to the survival of periampullary cancer patients.
Superhumps Behavior during Normal Outbursts in ER Ursae Majoris: Spectroscopy and Photometry

We undertook a 4-day spectroscopic observation and conducted a 13-day photometric study of an SU UMa-type dwarf nova, ER Ursae Majoris. The mean K-amplitude for the emission lines is 54 +/- 8 kms(-1) and the gamma velocity is 8 +/- 4 km s(-1) based on our spectroscopic results. A phase shift of 0.22 was also obtained. Our photometric observation confirms superhumps in normal outbursts of ER UMa. and reconciles contradictory observational results obtained by different authors. We find that superhumps possibly develop near each normal outburst maximum and fade out before the next Outburst maximum. If the observed humps were not late superhunips, but ordinary superhumps, much more theoretical work should be done to explain the new phenomena.
Non-Communicable Disease Preventive Screening by HIV Care Model share how this access benefits you. Your story matters

Importance The Human Immunodeficiency Virus (HIV) epidemic has evolved, with an increasing non-communicable disease (NCD) burden emerging and need for long-term management, yet there are limited data to help delineate the optimal care model to screen for NCDs for this patient population. Objective The primary aim was to compare rates of NCD preventive screening in persons living with HIV/AIDS (PLWHA) by type of HIV care model, focusing on metabolic/cardiovascular disease (CVD) and cancer screening. We hypothesized that primary care models that included generalists would have higher preventive screening rates. a cohort of 1565 PLWHA, distribution by HIV care model was 875 ID (56%), 90 generalists (6%), and 600 ID plus generalists (38%). Patients in the generalist group had lower odds of viral suppression but similar CD4 counts and ART exposure as compared with ID and ID plus generalist groups. In analyses adjusting for sociodemographic and clinical covariates and clustering within provider, there no significant in metabolic/ CVD or cancer screening among the three HIV care models.
Responses of Rj1 and rj1 Soybean Isolines to Inoculation with Bradyrhizobium japonicuml

We evaluated the symbiotic phenotypes of nodulation-restrictive and normal soybean isolines by inoculating Clark (genotypically Rj,Rjl) and mutant Clark-gi (genotypically did,) seedlings in plastic growth pouches. Nodules first appeared on Clark seedlings inoculated with Bradyrhizobiumjapoaicum USDA 94 after 6 days. The mean number of nodules per plant was 13.9 ± 0.8 after 24 days. In contrast, Clark-di seedlings first nodulated at 12 days, and the mean number of nodules per plant was only 1.7 ± 0.3 at 24 days. Segments from infectible zones of primary roots, i.e. near the position occupied by the root tip at the time of inoculation, were sectioned serially. Clark roots contained cortical cell divisions and a few infection threads in question mark-shaped root hairs by 2 days after inoculation. Typical nodules developed soon thereafter. Analogous serially sectioned segments from Clark-gi, roots lacked these responses. This prompted us to section nodules and adjacent tissues from other parts of Clark and Clark-di roots. Clark roots contained cortical cell divisions, many associated with infected root hairs. Cortical cell divisions occasionally were present in Clark-rjl, and a few infection threads were visible in surface cells. The presence of infection threads within Clark-di nodules was confirmed by transmission electron microscopy. Thus, although B. japoxicum USDA 94 fails to elicit the wild-type spectrum of responses in the infectible zones of
PERFORMANCE AND TIBIA CHARACTERISTICS OF BROILERS FED DIETS CONTAINING RAW OR TREATED OAK ACORN ( QUERCUS BRANTII LINDL )

Using a completely randomized design, a total of 360 one-day-old male and female broiler chicks were allocated to 6 experimental diets with four replicates (15 birds each), to evaluate the effects of raw or treated oak acorn (OA) on the performance and tibia characteristics of broilers. First diet was a corn-based diet (without OA) as the control, while other 5 diets contained 150 g/kg OA (raw or treated with distilled water, acetic acid, sodium hydrogen carbonate (Alkali) and traditional method). Birds were given starter and finisher diets from 1 to 21 and 22 to 42 d of age, respectively. The results indicated that all treatment methods significantly reduced the content of phenolic compounds. Dietary inclusion of raw OA had no deleterious effect on performance and tibia characteristics when compared to the control. Treatment with Alkali caused the highest overall body weight gain while traditional method resulted in worse performance compared to the raw OA. In conclusion, 150 g/kg raw OA could be included in broiler diets, without adverse effects on their performance or tibia characteristics. Chemical treatment, particularly using Alkali, has the potential to reduce the content of phenols and maybe improve the nutritional value of OA.
Capitalizing The Incremental Information Content of Accruals vs. Cash Flows for German Firms

Numerous empirical studies provide evidence on the value relevance of capitalizing expenditures on intangibles such as research & development (Lev and Sougiannis 1996, Hand 2003). However, accounting standards in many countries, such as the U.S. or Germany, prohibit capitalizing these. In this paper, we analyze the role of the capitalization of RND in the process of providing value relevant information. Several studies show that accrual information has superior predictive ability compared to cash flows (Wilson 1986, Dechow 1994). Reporting RND on the balance sheet leads to an additional accrual component of earnings which in turn serves as a conveyor of additional information. Within the framework of Dechow (1994) we analyze a sample of the 152 largest German listed companies over a period of five years (2002-2006). Our results show an added value of the accrual information provided by capitalized RND, in accordance with the literature surrounding the idea that accrual information is superior to cash information.