Miracle-dz/UniFAR-FTUs huggingface dataset:
The Effect of Resource Endowment and Governance on Human Capital Development of Sub-Saharan African Countries

: Human capital development is a process of enhancing the level of human capital capacity through attaining school and provides incentive-based training. The study helps to analyze the interaction between governance, resource and human capital in the study area. To conduct this study panel data type from 2005-2018 has been used, the data obtained from the World Bank database and the Penn world database and for analysis, both descriptive and system GMM panel data analysis have been used. The main reasons enforce to conduct this study is to checkup whether the resource endowment and governance important for human capital? Results of this study show that except for lag of human capital and voice and accountability other variables like resource endowment, labor participation rate, foreign direct investment, rule of law, and regularity quality are statistically and negatively affected human capital development. Given these results, the researcher recommended as, a responsible bodies in sub-Saharan African countries should be attained on the expansion of FDI that has to be especially concentrated on the manufacturing sector; an institution for good governance first should develop than formulate good governance principles, and finally develop resource merit institution in the favor of human capital development
Post-Transplant Cyclophosphamide after Matched Sibling and Unrelated Donor Hematopoietic Stem Cell Transplantation in Pediatric Patients with Acute Myeloid Leukemia

Non-relapse mortality due to GVHD and infections represents a major source of morbidity and mortality in pediatric HSCT recipients. Post-transplant cyclophosphamide (PTCy) has emerged as an effective and safe GVHD prophylaxis strategy, with improved GVHD and relapse-free survival in matched (related and unrelated) and mismatched haploidentical HSCT adult recipients. However, there are no published data in pediatric patients with acute myeloid leukemia who received matched-donor HSCT with PTCy. We demonstrate, in this case series, that the use of PTCy in this population is potentially safe, effective in preventing acute GVHD, does not impair engraftment, is associated with reduced non-relapse mortality, and does not hinder immune reconstitution post HSCT.
An In Vitro Approach for Investigating the Safety of Lipotransfer after Breast-Conserving Therapy

The application of lipotransfer after breast-conserving therapy (BCT) and irradiation in breast cancer patients is an already widespread procedure for reconstructing volume deficits of the diseased breast. Nevertheless, the safety of lipotransfer has still not been clarified yet due to contradictory data. The goal of this in vitro study was to further elucidate the potential effects of lipotransfer on the irradiated remaining breast tissue. The mammary epithelial cell line MCF-10A was co-cultured with the fibroblast cell line MRC-5 and irradiated with 2 and 5 Gy. Afterwards, cells were treated with conditioned medium (CM) from adipose-derived stem cells (ADSC), and the effects on the cellular functions of MCF-10A cells and on gene expression at the mRNA level in MCF-10A and MRC-5 cells were analyzed. Treatment with ADSC CM stimulated transmigration and invasion and decreased the surviving fraction of MCF-10A cells. Further, the expression of cytokines, extracellular, and mesenchymal markers was enhanced in mammary epithelial cells. Only an effect of ADSC CM on irradiated fibroblasts could be observed. The present data suggest epithelial–mesenchymal transition-like changes in the epithelial mammary breast cell line. Thus, the benefits of lipotransfer after BCT should be critically weighed against its possible risks for the affected patients.
Clinical Spectrum and Tumour Risk Analysis in Patients with Beckwith-Wiedemann Syndrome Due to CDKN1C Pathogenic Variants

Simple Summary Beckwith–Wiedemann syndrome (BWS) is an overgrowth disorder caused by imprinting or genetic alterations at the 11p15.5 locus. BWS is considered a spectrum disorder (BWSp) with an increased neoplasm incidence. CDKN1C variants have been reported in 5–10% of patients, with a higher incidence in familial cases. In this study, we examined the clinical and molecular features of all cases of BWSp identified by the Spanish Overgrowth Registry Initiative with CDKN1C variants, ascertained by Sanger sequencing or next-generation sequencing. We present 21 cases, 19 of which were classified as classical BWS and 1 that developed a mediastinal ganglioneuroma. Our study supports the high heterogeneity of the clinical features of BWSp and adds evidence on tumour development in this BWSp molecular subgroup. Genotype–phenotype correlation studies of patients with suspected BWS are essential for improving the diagnosis and assessing whether its cause can be directly related to the BWS clinical spectrum in the few cases that develop tumours. Abstract Beckwith–Wiedemann syndrome spectrum (BWSp) is an overgrowth disorder caused by imprinting or genetic alterations at the 11p15.5 locus. Clinical features include overgrowth, macroglossia, neonatal hypoglycaemia, omphalocele, hemihyperplasia, cleft palate, and increased neoplasm incidence. The most common molecular defect observed is hypomethylation at the imprinting centre 2 (KCNQ1OT1:TSS DMR) in the maternal allele, which accounts for approximately 60% of cases, although CDKN1C pathogenic variants have been reported in 5–10% of patients, with a higher incidence in familial cases. In this study, we examined the clinical and molecular features of all cases of BWSp identified by the Spanish Overgrowth Registry Initiative with pathogenic or likely pathogenic CDKN1C variants, ascertained by Sanger sequencing or next-generation sequencing, with special focus on the neoplasm incidence, given that there is scarce knowledge of this feature in CDKN1C-associated BWSp. In total, we evaluated 21 cases of BWSp with CDKN1C variants; 19 were classified as classical BWS according to the BWSp scoring classification by Brioude et al. One of our patients developed a mediastinal ganglioneuroma. Our study adds evidence that tumour development in patients with BWSp and CDKN1C variants is infrequent, but it is extremely relevant to the patient’s follow-up and supports the high heterogeneity of BWSp clinical features associated with CDKN1C variants.
The Effect of Institutional Ownership, Managerial Ownership, Liquidity, and Leverage on Financial Distress

Aims: This study aims to find empirical evidence and analyze the effect of institutional ownership, managerial ownership, liquidity, and leverage on financial distress. In addition, this research can also be used as a reference for further researchers as well as a reference for stakeholders (investors, creditors, and the government) in making relevant and reliable decisions. Study Design: The method used is quantitative research with secondary data taken from the company's financial statements with data collection techniques using purposive sampling. Place and Duration of Study: The population in this study are manufacturing companies in the consumer goods industry sector listed on the Indonesia Stock Exchange during 2018-2020. The number of research samples is 63 data. Methodology: Analysis of the data used is multiple linear regression analysis. Results: The results of this study indicate that: (1) Institutional Ownership has no significant effect on Financial Distress. (2) Managerial Ownership has no significant effect on Financial Distress. (3) Liquidity has a positive and significant effect on Financial Distress. (4) Leverage has a negative and significant effect on Financial Distress.
Inbound tourism and income inequality: the role of banking sector development

Abstract This study empirically confirms the nonlinear effects of banking sector development on the inbound tourism–income inequality nexus by adopting the panel smooth transition regression model for 102 economies. Findings for the full sample suggest that although inbound tourism can reduce income inequality, this effect gradually weakens as the banking sector develops. In high-income economies, an increase in international tourism receipts first exacerbates and then decreases income inequality as the banking sector develops. Moreover, a well-developed banking sector could improve income distribution. In low-income economies, the international tourism receipts–inequality nexus differs from the international tourist arrivals–inequality nexus under various levels of banking sector development. International tourism receipts initially decrease income inequality and then increase it when the banking sector develops to a certain degree. However, international tourist arrivals first deteriorate income distribution and then improve it as the banking sector develops. From a policy perspective, appropriate policies should be implemented to achieve a balance between the banking sector, inbound tourism, and income inequality in high-income and low-income economies and ensure sustainable development.
Comparative Biology of Three Coccinellid Predators on Cowpea Aphid Aphis Craccivora

Laboratory experiment was conducted to study the biology of coccinellid predators from agroecosystems of Odisha. About 17 species were identified, the most important being Coccinella septempunctata, Coccinella transversalis and Cheilomenes sexmaculata predating on aphids infesting cowpea. The biology of these when evaluated indicated that C. septempunctata was the largest, and C. sexmaculata the smallest; grubs of all the three are susceptible to the rising temperature. The total developmental period was maximum during January and the least during May for all species. Total larval period was 11.9 ± 2.34, 12.1 ± 6.19 and 12.6 ± 0.01 days in January and 8.2 ± 0.07, 7.00 ± 0.01 and 7.9 ± 0.06 during May with C. septempunctata, C. transversalis and C. sexmaculata, respectively; developmental periods for these were observed to be 22.4 ± 0.67, 20.2 ± 1.46 and 17.4 ± 0.82 days during January, and 15.2 ± 0.01, 11.5 ± 0.39 and 12.3 ± 0.61 days during May, respectively. Prepupae and pupae were the least affected by the fluctuations in temperature.
Tools Designed to Support Self-Regulated Learning in Online Learning Environments: A Systematic Review

Self-regulated learning (SRL) is a crucial higher-order skill required by learners of the 21st century, who will need to become lifelong learners to adapt to the continually changing environments. Literature provides examples of tools for scaffolding SRL in online environments. In this article, we provide the state-of-the-art concerning tools that support SRL in terms of theoretical models underpinning development, supported SRL processes, tool functionalities, used data and visualizations. We reviewed 42 articles published between 2008 and 2020, including information from 25 tools designed to support SRL. Our findings indicate that: 1) many of the studies do not explicitly specify the SRL theoretical model used to guide the design process of the tool; 2) goal setting, monitoring, and self-evaluation are the most prevalent SRL processes supported through functionalities, such as content navigation, user input forms, collaboration features, and recommendations; 3) the relationship between tool functionalities and SRL processes are rarely described; and 4) few tools assess the impact on learners’ SRL process and learning performance. Finally, we highlight some lessons learned that might contribute to implementing future tools that support learners’ SRL processes.
Deduction with symbolic constraints

A framework for first-order constrained deduction is proposed in this paper. The syntax and semantics of symbolic constraints and constrained formulae are defined. Constrained deduction rules are given for equational logic and for first-order logic with equality. They are applied to clausal theorem proving, unfailing completion and completion modulo a set of axioms.
Landslide Susceptibility Modeling Using Integrated Ensemble Weights of Evidence with Logistic Regression and Random Forest Models

The main aim of this study was to compare the performances of the hybrid approaches of traditional bivariate weights of evidence (WoE) with multivariate logistic regression (WoE-LR) and machine learning-based random forest (WoE-RF) for landslide susceptibility mapping. The performance of the three landslide models was validated with receiver operating characteristic (ROC) curves and area under the curve (AUC). The results showed that the areas under the curve obtained using the WoE, WoE-LR, and WoE-RF methods were 0.720, 0.773, and 0.802 for the training dataset, and were 0.695, 0.763, and 0.782 for the validation dataset, respectively. The results demonstrate the superiority of hybrid models and that the resultant maps would be useful for land use planning in landslide-prone areas.
Procedural Efficiency, Efficacy, and Safety of High-Power, Short-Duration Radiofrequency Ablation Delivered by STSF Catheter for Paroxysmal Atrial Fibrillation

Objectives To investigate the procedural efficiency, efficacy, and safety of high-power, short-term radiofrequency ablation delivered by the SmartTouch Surround Flow (STSF) catheter for paroxysmal atrial fibrillation (AF). Methods We retrospectively analyzed a total of 72 patients who were admitted with paroxysmal AF, and who underwent radiofrequency catheter ablation (RFCA) for the first time. Of these patients, 36 cases underwent low-power, long-duration (LPLD, (30–35 W/20–40 s) pulmonary vein isolation (PVI) delivered by an SmartTouch (ST) catheter (control group), and the other 36 cases underwent high-power, short-duration (HPSD, (45–50 W/10–20 s) PVI delivered by a STSF catheter (study group). The baseline data, duration of PVI, procedural time, fluoroscopy time, the rate of first-pass isolation, irrigation perfusion, eschar and steam pop occurrences, intraoperative complications, and the rate of stable sinus rhythm maintenance following a blanking period of three months were analyzed between the two groups. Results The isolation time of bilateral PVI and procedural time in the study group were markedly less than in controls (p < 0.01). The rate of first-pass isolation in the study group was significantly higher than in the control group (95.8% vs. 84.7%, p = 0.023), while the fluid perfusion in the study group was approximately 20% less than that in the control group (767 ± 171 vs. 966 ± 227 ml, p < 0.001). We observed no severe complications in any patients. The rate of freedom from AF recurrences following a blanking period of three months showed a tendency to be higher than in controls (93.9% vs. 87.1%, p = 0.348). Conclusions The HPSD strategy delivered by the STSF catheter was superior to conventional LPLD ablation through the ST catheter with respect to efficiency, acute procedural effectiveness, short-term safety, and the risk of heart failure in patients with paroxysmal AF.
Virtual Reality Greenspaces: Does Level of Immersion Affect Directed Attention Restoration in VR Environments?

Research on attention restoration theory has provided consistent results over the years, and exposure to nature has been found to significantly improve and restore directed attention fatigue. However, rapid urbanisation has made it increasingly difficult for human beings to interact with unpolluted nature. Countries such as Singapore began to integrate nature into city planning and into the designs of buildings to help resident satisfaction and well-being. Local studies have had contradictory outcomes; residents report significantly higher restoration and affect towards vertical integrated greeneries, but many would still prefer traditional on-the-ground foliage. Interest in outdoor greenspaces is variable because Singapore’s high heat and humid climate make it uncomfortable to interact with outside nature for prolonged periods. The current study tested alternative modalities that can provide residents with on-the-ground foliage interactions, without the discomfort of being outdoors. Virtual exposures with different levels of immersion (high and low) and types of scenes (nature and urban) were tested for effects on perceived presence, perceived restoration and objective restoration. A total of 120 adult participants completed the study, which revealed that a virtual reality-nature condition provided significantly superior directed attention restoration and higher presence ratings. Immersive tendency did not affect perceived presence; neither did it moderate the relationship between perceived presence and its corresponding perceived restoration.
The Efficacy of Parent Training Interventions with Parents of Children with Developmental Disabilities

Parenting children with developmental disabilities (DD) can be generally characterized by a considerable psychological burden. The effects on parental and familial psychological well-being and, consequently, on children’s developmental outcomes should not be underestimated, especially in early childhood. The current review aims to advance our understanding of the key factors (e.g., formats, sample characteristics, research design) that characterize parent training interventions, and that could be related to their outcomes, to guide researchers and clinical practitioners to develop and provide efficient programs. Studies were identified via an Internet search from three electronic databases, following PRIMSA guidelines. Studies published until November 2021 were taken into account. The initial search yielded a total of 2475 studies. Among them, 101 studies were fully reviewed. Finally, ten of the studies, which met all the inclusion criteria, formed the basis for this review. Participants’ characteristics, main features of the interventions (i.e., study design, structure, and contents), outcome variables and treatment efficacy were deeply examined and discussed. Key factors of parent training interventions with parents of children affected by DD are enlightened, to guide researchers and clinicians in the design and implementation of tailored specific programs, aimed to sustain parenting and foster children’s developmental outcomes, from early stages of life.
Evaluation of angiogenic and embryotoxic activity of the extract of Anadenanthera peregrina (Angico-do-Cerrado)

The genus Anadenanthera has been reported in the literature with antioxidant, anti-inflammatory, antimicrobial effect and healing action in wound treatment. The study aimed to evaluate, in vivo, the angiogenic and embryotoxic activities of A. peregrina extract. Angiogenesis in chicken embryo egg chorioallantoic membrane and zebrafish embryotoxicity was performed. A. peregrina extract at concentrations 62 mg mL-1 and 124 mg mL-1 were angiogenic. For embryotoxicity, the mortality rate increased with increasing concentration and increased dose and time dependent embryotoxicity was observed. The lethal concentration (LC50) ranged from 0.331mg mL-1 over the 24 hpf period to 0.007 mg mL-1 at 168 hpf (Δ% = -97.9), decreasing with increasing exposure. The heart rate decreased progressively and significantly with increasing concentration at all tested exposure times. In conclusion, it was evidenced that the extract of Anadenanthera peregrina has angiogenic activity. Nonetheless, embryotoxic effects were observed at high concentrations.
Statistical Multiscale Segmentation: Inference, Algorithms and Applications

This thesis mainly concerns change-point models with independent observations from an exponential family with constant mean in between change-points. An inferential scheme for estimation and confidence statements based on a multiscale statistic is provided, which allows for efficient and accurate detection of multiple change-points. A universal bound for the asymptotic null-distribution of the considered multiscale statistic is derived. Based on this, the probability of over- and underestimation of change-points is bounded explicitly. From these bounds, model consistency is obtained and (asymptotically) honest confidence sets for the unknown change-point function and its change-points are constructed. The change-point locations are estimated at the minimax rate up to a logarithmic term. Moreover, the optimal detection rate of vanishing signals is attained. It is shown how dynamic programming can be used for efficient computation of estimators, confidence intervals and confidence bands for the change-point function. The performance and robustness of the approach are illustrated in various simulations and applications.
AN INVESTIGATION INTO THE CHARACTERISTICS OF LIGHTNING AS IT INTERACTS WITH TOWERS

Tall structures can be the subject of lightning interaction and often lead to an increased cloud-to-ground (CG) ﬂash rate in the vicinity. Lightning that interacts with towers can take the form of traditional CG ﬂash, beginning in-cloud and propagating downward to connect with the tower, but ﬂashes may also begin at the tower itself. However, the nature and overall percentage of lightning propagating from tower locations is unknown. This study examines lightning interactions with 10 communication towers from 213 to 610 m tall across Oklahoma using CG data from the National Lightning Detection Network (NLDN) and VHF data from the Oklahoma Lightning Mapping Array (LMA), and radar data from the Weather Service Radar - 1988 Doppler (WSR-88D) network. The NLDN data was used to ﬁrst determine the speciﬁc time (in milliseconds), latitude, and longitude of lightning that potentially interacted with these towers. The LMA data was then used to examine the detailed breakdown of each ﬂash as well as any nearby lightning ﬂashes. 45 individual lightning ﬂashes occurring within 1 km of these tower locations were examined in the winter, summer, and fall of 2010 to determine: (1) the initiation location and height, (2) the size (temporally and spatially) of the lightning ﬂash, (3) any seasonal dependence, and (4) the associated the storm structure and storm type. Using these factors, these lightning ﬂashes were classiﬁed to better understand the overall percentage of lightning triggered by the tower and the environmental factors contributing to the occurrence of upward- triggered lightning. Of the 45 ﬂashes, 60% of CG ﬂashes interacted directly with the tower, 20% were classiﬁed as in-cloud ﬂashes, and 20% of ﬂashes were classiﬁed as upward lightning, mainly triggered by a nearby preceding CG. The initiation distance between these three main ﬂash types (44/45 overall ﬂashes) occurred between 7-9 km from the tower. CG ﬂashes, beginning in-cloud and terminating at the tower, were the dominant ﬂash type across all seasons, independent of the convective mode and the storm structure.