Miracle-dz/UniFAR-FTUs huggingface dataset:
Comparative efficacy and safety of antiplatelet or anticoagulant therapy in patients with chronic coronary syndromes after percutaneous coronary intervention: A network meta-analysis of randomized controlled trials

Aimed to evaluate and compare the interactive effects of different antiplatelet or anticoagulation strategies in patients with chronic coronary syndromes (CCS) after percutaneous coronary intervention (PCI). Randomized controlled trials comparing different antiplatelet or anticoagulant strategies in patients with CCS after PCI were included. The primary outcomes were major adverse cardiovascular event (MACE), mortality, ischemic and bleeding events. Compared to aspirin alone, addition of prasugrel or ticagrelor to aspirin resulted in lower risk of myocardial infarction (MI) [odds ratio (OR): 0.38 (95% confidence interval 0.38–0.62); 0.810–0.84 (0.69–0.98)] and any stroke [0.56 (0.42–0.75)] at the expense of increased risk of major bleeding [1.79 (1.34–2.39); 2.08–2.38 (1.56–3.28)], whereas, clopidogrel monotherapy reduced the risk of any stroke, major bleeding, and intracranial bleeding. On subgroup analysis, compared with aspirin alone, addition of prasugrel resulted in lower MACE [0.72 (0.60–0.86)], MI [0.48 (0.38–0.62)], and stent thrombosis [0.29 (0.09–0.91)], whereas, addition of rivaroxaban 2.5 mg resulted in lower risk of MACE [0.72 (0.60–0.87)], cardiac death [0.71 (0.52–0.98)] and any stroke [0.65 (0.45–0.95)], but not reduced MI. Both prasugrel and rivaroxaban 2.5 mg increased major bleeding [1.79 (1.34–2.39); 1.72 (1.33–2.22)]. Clopidogrel monotherapy was associated with lower MACE [0.72 (0.58–0.90)], any stroke [0.42 (0.24–0.73)], and major bleeding [0.62 (0.40–0.96)]. Adding prasugrel or ticagrelor led to a reduced incidence of MI and prasugrel was also found to reduce the risk of MACE and stent thrombosis in CCS patients with low risk of bleeding after PCI. Clopidogrel monotherapy has advantage in reducing MACE, stroke, and major bleeding events in CCS patients at high risk of bleeding after PCI. Systematic Review Registration: https://clinicaltrials.gov/, PROSPERO Identifier: CRD 42021291050.
Critical period of grass weed control in ALS-tolerant grain sorghum (Sorghum bicolor) is affected by planting date and environment

Field experiments were conducted at two locations in North Carolina (Clayton and Rocky Mount) to determine the influence of row spacing and planting date on the critical period of weed control (CPWC) of grass weeds in ALS-tolerant grain. Grain sorghum was planted in May and June 2019, with either a 38 or 91 cm row spacing using an ALS-tolerant sorghum variety. Treatments consisted of “weedy” or “weed-free” plots up to 2, 3, 5, and 7 weeks after crop planting (WAP) and two control treatments of weedy and weed-free all season. Selection of grass weed species was achieved by controlling broadleaf weeds with a premix of bromoxynil plus pyrasulfutole at a rate of 264 g a.i. ha-1.Grass weeds were controlled using nicosulfuron at a rate of 69 g of a.i. ha-1. The CPWC was significantly different across locations. Row spacing and planting date factors did not influence the CPWC at Clayton. Planting date was a significant factor for the CPWC at Rocky Mount, however row spacing did not have any effect on the CPWC. Results for the CPWC are presented in terms growing degree days (GDD) from the date of crop sowing. The CPWC for grass weeds in grain sorghum at Clayton was from 368 to 849 GDD. The CPWC at Rocky Mount for May-planted grain sorghum was from 405 to 876 GDD, while the CPWC for June-planted grain sorghum ranged from 228 to 1042 GDD. These results demonstrate that cultural and environmental factors may influence the beginning, duration and end of the CPWC.
Exploring an EAP writing teacher's adaptive expertise and adaptive teaching practices from a CDST perspective

Teachers' adaptive expertise (TAE) has received increasing attention in the current English as foreign language (EFL) teaching field, however, it has seldom been examined with adaptive practices by teachers in on-going classes among existing literature. Adopting a mixed-method design with data triangulation, this study was conducted to explore the complexity of teachers' adaptive expertise (TAE) and adaptive teaching practices that an EAP writing teacher demonstrated in academic writing courses, from a Complex Dynamic Systems Theory (CDST) perspective. Semi-structured interviews, classroom observations, and questionnaires were arranged to collect qualitative and quantitative data from an EAP writing teacher and 43 EFL learners in a Chinese university. Thematic analysis and SPSS were mainly used in the current work for data analysis. Our findings confirmed (1) the complexity of TAE and ATP with specific features of non-linearity, interconnectedness, and self-organization, which are classic CDST characteristics; (2) the TAE evolved with meta-cognitive, cognitive, affective and social components that are intertwined and contributed to the teacher's adaptive teaching practices (ATP) in her academic writing course; (3) being facilitated by TAE, the teacher's adaptive teaching practices significantly enhanced EFL learners, learning motivation of academic writing and their learning efficiency. Findings of the current work pave the way for future studies in researching TAE and ATP with a thorough consideration of language teachers, students and contexts from the CDST perspective. Moreover, pedagogical contributions are highlighted through the detailed examinations of the EAP writing teacher's ATP, including the class design, teaching plans, and methods, which would be fruitful for the development of tertiary EAP writing research.
Effects of visual landscape on subjective environmental evaluations in the open spaces of a severe cold city

The environmental quality and subjective environmental evaluations in urban open spaces are essential. In this study, the effects of building, green, and water landscapes, which are typical visual landscapes, on the subjective environmental evaluations (including thermal sensation and comfort, and overall comfort) in different seasons were analyzed by conducting questionnaire surveys and field measurements in a severely cold city. It was found that the visual landscapes significantly affected subjective environmental evaluations in winter and summer, but there were no effects in the transitional season. In summer, compared with the building and green landscape, the thermal sensation vote in the water landscape was the lowest at 0.4, and the differences were 0.3∼1.0. However, the thermal comfort vote in the water landscape was found to be 0.6 times higher. In winter, the thermal sensation and comfort votes in the water landscape were the lowest, the average evaluation under different UTCI was –2.2, and the results were similar for the overall comfort evaluation. In addition, the subjects believed that green and water landscapes improved thermal comfort and had more significant effects on improving the environmental temperature in the three seasons. Additionally, visual landscape evaluations significantly affect subjective environmental evaluations in summer than in the winter and transitional season; the higher the visual landscape evaluation, the better the thermal and overall comfort.
Analysis based on neural representation of natural object surfaces to elucidate the mechanisms of a trained AlexNet model

Analysis and understanding of trained deep neural networks (DNNs) can deepen our understanding of the visual mechanisms involved in primate visual perception. However, due to the limited availability of neural activity data recorded from various cortical areas, the correspondence between the characteristics of artificial and biological neural responses for visually recognizing objects remains unclear at the layer level of DNNs. In the current study, we investigated the relationships between the artificial representations in each layer of a trained AlexNet model (based on a DNN) for object classification and the neural representations in various levels of visual cortices such as the primary visual (V1), intermediate visual (V4), and inferior temporal cortices. Furthermore, we analyzed the profiles of the artificial representations at a single channel level for each layer of the AlexNet model. We found that the artificial representations in the lower-level layers of the trained AlexNet model were strongly correlated with the neural representation in V1, whereas the responses of model neurons in layers at the intermediate and higher-intermediate levels of the trained object classification model exhibited characteristics similar to those of neural activity in V4 neurons. These results suggest that the trained AlexNet model may gradually establish artificial representations for object classification through the hierarchy of its network, in a similar manner to the neural mechanisms by which afferent transmission beginning in the low-level features gradually establishes object recognition as signals progress through the hierarchy of the ventral visual pathway.
The effect of the online eye movement desensitization and reprocessing early intervention protocol (EMDR R-TEP) for the risk groups with post-traumatic stress symptoms during the COVID-19 pandemic

The aim of the research is to investigate the effect of eye movement desensitization and reprocessing (EMDR) therapy on post-traumatic stress disorder (PTSD) levels of individuals who can be defined as high-risk groups during the pandemic. Therefore, the online EMDR R-TEP Protocol was applied to a total of 154 individuals working with coronavirus patients, frontline professionals (Doctors, Nurses, Paramedics, Polices, Red Crescent), relatives of coronavirus patients, coronavirus patients, and relatives of someone who died from coronavirus and the PTSD symptom level before, after, and 1 month after therapy was measured and examined. A personal information form and impact of events scale were used to collect data. Analyses showed that EMDR therapy was effective in reducing the PTSD level in all groups. The PTSD levels of frontline professionals continued to decrease until the follow-up test but remained the same in the other groups.
Inverse association of serum carotenoid levels with prevalence of hypertension in the general adult population

Carotenoid levels are inversely associated with blood pressure (BP). This study focused on the effects of individual and combined serum carotenoids on BP and hypertension, which have not been established to date. Data from National Health and Nutrition Examination Survey (NHANES) 2001–2006 were analyzed in this cross-sectional study. Multivariate logistic, linear, and weighted quantile sum (WQS) regression analyses were applied to explore the associations of six serum carotenoids (α-carotene, β-cryptoxanthin, lutein/zeaxanthin, trans-lycopene, trans-β-carotene, and cis-β-carotene), individually and in combination, with BP/hypertension. The linearity of correlations was further assessed using restricted cubic spline (RCS) regression. A total of 11,336 adults were included for analysis. Data from multivariate models showed that all six carotenoids were independently and negatively associated with both systolic blood pressure (SBP) and diastolic blood pressure (DBP; all p < 0.05). Compared to the first quartile, the fourth quartile of α-carotene (odds ratio [OR] = 0.64 [0.52–0.77]), β-cryptoxanthin (OR = 0.74 [0.60–0.90]), trans-β-carotene (OR = 0.50 [0.40–0.61]), and cis-β-carotene (OR = 0.47 [0.35–0.64]) were significantly and inversely related to hypertension (all p < 0.05). Moreover, WQS analysis revealed that the combination of all six serum carotenoids was negatively associated with BP and hypertension (all P<0.001), among which trans-β-carotene was the most significant contributor to the protective effect against hypertension (weight, 59.50%). Dose-response analyses demonstrated a linear inverse association of all carotenoids with hypertension (p for non-linearity > 0.05). Our collective findings indicate that higher levels of all six mixed serum carotenoids are correlated with decreased prevalence of hypertension, among which β-carotene exerts the most significant effect, which may provide a basis and direction for further studies.
Psychosocial stress accompanied by an unhealthy eating behavior is associated with abdominal obesity in Korean adults: A community-based prospective cohort study

Psychosocial stress is recognized as a potential modulator of eating behavior. Psychosocial stress also constitutes an independent risk factor for the development of non-communicable diseases. This study examined the gender-stratified associations between perceived stress, eating behavior, and abdominal obesity in 4,411 adults aged 40–69 years during a 10-year follow-up of the Korean Genome and Epidemiology Study (KoGES). Psychosocial stress was evaluated using the Psychosocial Wellbeing Index Short Form (PWI-SF), and eating behavior was analyzed with a focus on the dietary variety score (DVS). The Cox's proportional hazard model was used to examine the risk of abdominal obesity according to stress levels. Higher stress levels were associated with lower DVS in women. Lower DVS scores were positively associated with the consumption of grains and refined grains but was negatively associated with the consumption of fruits. The DVS was not significantly associated with stress levels among men. Prospectively, the highest tertile of grains and refined grains consumption showed an increased risk of abdominal obesity compared to the lowest tertile in women (HR: 1.36, 95% CI: 1.04–1.78, p < 0.05; HR: 1.28, 95% CI: 1.03–1.59, p < 0.05, respectively). By contrast, in all participants, the highest tertile of fruits consumption decreased the risk of abdominal obesity compared to the lowest tertile (men, HR: 0.56, 95% CI: 0.45–0.70, p < 0.01; women, HR: 0.51, 95% CI: 0.40–0.65, p < 0.01). Furthermore, high stress levels showed a borderline significant association with the risk of abdominal obesity only in women (HR: 1.27, 95% CI: 1.00–1.59, p < 0.05). These findings suggested that psychosocial stress might contribute to abdominal obesity by interacting with eating behavior represented by a low DVS. The approach to consume a diet with a high DVS might help decrease the risk of abdominal obesity among people in stressful environments.
Gastrointestinal Talaromyces marneffei infection in a patient with AIDS: A case report and systematic review

Talaromyces marneffei is a thermally dimorphic fungus that affects multiple organs and frequently invades immunocompromised individuals. However, only a few studies have reported the presence of intestinal infection associated with T. marneffei. Herein, we reported a case of intestinal T. marneffei infection in a man who complained of a 1-month history of intermittent fever, abdominal pain, and diarrhea. The result of the human immunodeficiency virus antibody test was positive. Periodic acid-Schiff and Gomorrah’s methylamine silver staining of the intestinal biopsy tissue revealed T. marneffei infection. Fortunately, the patient’s symptoms rapidly resolved with prompt antifungal treatment. In addition, we summarized and described the clinical characteristics, management, and outcomes of patients with intestinal T. marneffei infection. A total of 29 patients were identified, the majority of whom (65.52%) were comorbid with acquired immunodeficiency syndrome. The main clinical features included anemia, fever, abdominal pain, diarrhea, weight loss, and lymphadenopathy. The transverse and descending colon, ileocecum, and ascending colon were the most common sites of lesions. A considerable number of patients (31.03%) developed intestinal obstruction, intestinal perforation, and gastrointestinal bleeding. Of the 29 patients, six underwent surgery, 23 survived successfully with antifungal treatment, five died of T. marneffei infection, and one died of unknown causes. T. marneffei intestinal infection should be considered when immunodeficient patients in endemic areas present with non-specific symptoms, such as fever, abdominal pain, and diarrhea. Appropriate and timely endoscopy avoids delays in diagnosis. Early aggressive antifungal therapy improves the clinical outcomes of patients.
Older males whistle better: Age and body size are encoded in the mating calls of a nest-building amphibian (Anura: Leptodactylidae)

Courtship acoustic displays in anuran amphibians are energetically costly and risky, but have a major role in mating success since they encode relevant information regarding the caller’s identity and status. Age and size are essential traits shaping fitness, reproductive success and life-history strategies, and thus are expected to also have a role in courtship displays. We tested this assumption in a species of nest-building frogs, Leptodactylus bufonius, in northern Argentina. We conducted the first detailed quantitative description of the males’ mating calls and assessed the effects of biological traits (i.e., body size parameters and individual age) and local climate (i.e., air temperature and humidity) on the main acoustic features of these calls (i.e., call duration, inter-call duration, dominant frequency, and dominant frequency modulation). The calls were short (mean ± SE, 0.163 ± 0.004 s), whistle-like, single notes with harmonic structure. The dominant frequency (1381.7 ± 16.2 Hz) decreased with arm length (χ2 = 5.244, df = 1, p = 0.022) and had an upward modulation (456.4 ± 11.0 Hz) which increased with age (χ2 = 4.7012, df = 1, p = 0.030). Call duration and dominant frequency were the most static parameters at intra-individual level, indicating their role in individual recognition. Temperature and humidity shaped the temporal acoustic parameters, and the dominant frequency. Our findings suggest that the acoustic features of the mating calls in amphibians could promote female mate choice in relation to both size and age and open up new questions for future research: are females more attracted to older males, and what are the specific costs and benefits? We suggest that mating calls may direct female preferences toward males of certain size and age classes, ultimately shaping the life-history strategies in a given population. Finally, we found discrepancies in the mating calls of L. bufonius recorded from Corrientes and those previously described from other populations, which suggests that multiple species may have been recorded under the same name.
Small Chimera States without Multistability in a Globally Delay-Coupled Network of Four Lasers

We present results obtained for a network of four delay-coupled lasers modelled by Lang-Kobayashi-type equations. We find small chimera states consisting of a pair of synchronized lasers and two unsynchronized lasers. One class of these small chimera states can be understood as intermediate steps on the route from synchronization to desynchronization and we present the entire chain of bifurcations giving birth to them. This class of small chimeras can exhibit limit-cycle or quasiperiodic dynamics. A second type of small chimera states exists apparently disconnected from any region of synchronization, arising from pair synchronization inside the chaotic desynchronized regime. In contrast to previously reported chimera states in globally coupled networks, we find that the small chimera state is the only stable solution of the system for certain parameter regions, i.e. we do not need to specially prepare initial conditions.
Measuring the extent of convective cores in low-mass stars using Kepler data: towards a calibration of core overshooting

Our poor understanding of the boundaries of convective cores generates large uncertainties on the extent of these cores and thus on stellar ages. Our aim is to use asteroseismology to consistently measure the extent of convective cores in a sample of main-sequence stars whose masses lie around the mass-limit for having a convective core. We first test and validate a seismic diagnostic that was proposed to probe in a model-dependent way the extent of convective cores using the so-called $r_{010}$ ratios, which are built with $l=0$ and $l=1$ modes. We apply this procedure to 24 low-mass stars chosen among Kepler targets to optimize the efficiency of this diagnostic. For this purpose, we compute grids of stellar models with both the CESAM2k and MESA evolution codes, where the extensions of convective cores are modeled either by an instantaneous mixing or as a diffusion process. Among the selected targets, we are able to unambiguously detect convective cores in eight stars and we obtain seismic measurements of the extent of the mixed core in these targets with a good agreement between the CESAM2k and MESA codes. By performing optimizations using the Levenberg-Marquardt algorithm, we then obtain estimates of the amount of extra-mixing beyond the core that is required in CESAM2k to reproduce seismic observations for these eight stars and we show that this can be used to propose a calibration of this quantity. This calibration depends on the prescription chosen for the extra-mixing, but we find that it should be valid also for the code MESA, provided the same prescription is used. This study constitutes a first step towards the calibration of the extension of convective cores in low-mass stars, which will help reduce the uncertainties on the ages of these stars.
Spontaneous chiral symmetry breaking and the Chiral Magnetic Effect for interacting Dirac fermions with chiral imbalance

We report on a mean-field study of spontaneous breaking of chiral symmetry for Dirac fermions with contact interactions in the presence of chiral imbalance, which is modelled by nonzero chiral chemical potential. We point out that chiral imbalance lowers the vacuum energy of Dirac fermions, which leads to the increase of the renormalized chiral chemical potential upon chiral symmetry breaking. The critical coupling strength for the transition to the broken phase is slightly lowered as the chiral chemical potential is increased, and the transition itself becomes milder. Furthermore, we study the chiral magnetic conductivity in different phases and find that it grows both in the perturbative weak-coupling regime and in the strongly coupled phase with broken chiral symmetry. In the strong coupling regime the chiral magnetic effect is saturated by vector-like bound states (vector mesons) with mixed transverse polarizations. General pattern of meson mixing in the presence of chiral imbalance is also considered. We discuss the relevance of our study for Weyl semimetals and strongly interacting QCD matter. Finally, we comment on the ambiguity of the regularization of the vacuum energy of Dirac fermions in the presence of chirality imbalance.
Equivariant Complex Cobordism and Geometric Orientations

We calculate the cobordism ring of stably almost complex manifolds with involution, and investigate the equivariant spectrum which represents it. We introduce the notion of geometrically oriented spectra, which extends the notion of complex oriented spectra, and of which the geometric cobordism spectrum is the universal example. Other examples of geometrically oriented spectra include the Eilenberg-Maclane spectrum associated to a constant Mackey functor, and the connective cover of equivariant complex K theory. On the algebraic side, we define and study filtered equivariant formal group laws, which are the algebraic structures determined by geometrically oriented spectra. We prove some of the fundamental properties of filtered equivariant formal group laws, as well as a universality statement for the filtered equivariant formal group law determined by the geometric complex cobordism spectrum.
Shape/Phase Transitions and Critical Point Symmetries in Atomic Nuclei

Shape/phase transitions in atomic nuclei have first been discovered in the framework of the Interacting Boson Approximation (IBA) model. Critical point symmetries appropriate for nuclei at the transition points have been introduced as special solutions of the Bohr Hamiltonian, stirring the introduction of additional new solutions describing wide ranges of nuclei. A short review of these recent developments will be attempted.