Miracle-dz/UniFAR-FTUs huggingface dataset:
Pattern Of Sexually Transmitted Infections In A Reference Clinic Of Aminu Kano Teaching Hospital, Kano

Background: Sexually transmitted infections (STIs) are common communicable diseases worldwide and constitute part of major cases seen at Aminu Kano Teaching Hospital (AKTH), Kano. Objective: To determine the pattern of STIs and other associated clinical conditions/ sequelae among patients attending skin/ STI referral clinic at AKTH, Kano. Methods: A prospective study with respect to the spectrum of STIs among patients who attended the Skin/STI clinic and who were physically examined and made to undergo appropriate laboratory diagnostic tests during the period November, 1998 – October, 2000 is presented. Results: A total of Ninety patients were investigated comprising 53 (58.89%) women and 37 (41.11%) men. Candidiasis (vulvovaginitis) constituted the highest 21 (23.33%) of STI recorded followed by HIV/AIDS 13 (14.44%), pelvic inflammatory disease (PID) 12 (13.33%), genital warts 9 (10%) and non – gonococcal urethritis (NGU), 8 (8.89%) in that order. Others were lues, chancroid and Tinea cruris infections constituting 5.56% each. Gonorrhea and scabies made up 3 (3.33%) each of the cases while genital herpes including infective Herpes zoster and Molluscum contagiosum associated infections accounted for 2.22% each of the cases. Conclusion: The patients presented with significant range of STIs with some showing similar prevalence rate. The majority (approximately 37%) of the clinical conditions were associated with bacterial agents while parasite related cases were the least encountered. There was relatively high occurrence of vulvovaginitis caused by Candida albicans in female patients while genital herpes, Herpes zoster and M. contagiosum associated infections were the least seen. Key words: Pattern, Spectrum, STIs, Patients, Skin/STI-referral clinic, AKTH. Highland Medical Research Journal Vol.2(2) 2004: 55-60
3-Methyl-N-phenylbenzamide

The conformation of the C=O bond in the structure of the title compound, C14H13NO, is anti to the meta-methyl substituent in the benzoyl ring. The conformations of the N—H and C=O bonds in the amide group are also anti to each other. The asymmetric unit of the structure contains two molecules. The bond parameters are similar to those in N-(phenyl)benzamide, 2-methyl-N-(phenyl)benzamide and other benzanilides. The amide group –NHCO– forms dihedral angles of 20.97 (34) and 45.65 (19)° with the benzoyl rings, and 41.54 (25) and 31.87 (29)° with the aniline rings, in the two independent molecules. The benzoyl and aniline rings adopt dihedral angles of 22.17 (18) and 75.86 (12)° in the two independent molecules. In the crystal structure, molecules are linked into chains by intermolecular N—H⋯O hydrogen bonds.
2-Cyano-N′-[(E)-1-(2-oxo-2H-chromen-3-yl)ethylidene]acetohydrazide

In the title compound, C14H11N3O3, the chromene ring is almost planar, with a maximum deviation of 0.065 (2) Å from the mean plane for one of the C atoms. In the crystal, inversion dimers linked by pairs of N—H⋯O hydrogen bonds generate R 2 2(8) loops. The dimers are linked by C—H⋯N and C—H⋯O interactions into a three-dimensional network. An aromatic π–π stacking interaction, with a centroid–centroid distance of 3.562 (10) Å, is also observed.
(E)-3-[2-(Trifluoro­meth­yl)phenyl­imino­meth­yl]benzene-1,2-diol

The title compound, C14H10NO2F3, adopts the enol-imine tautomeric form. There are two independent mol­ecules in the asymmetric unit, with the two aromatic rings inclined at 38.97 (9) and 37.68 (9)°. Each of the independent mol­ecules forms O—H⋯O hydrogen-bonded centrosymmetric R22(10) dimers.
N,N′-Bis(1,3-dimethyl­imidazolidin-2-yl­idene)-2,2′-dithio­dianiline

The mol­ecular structure of the title compound, C22H28N6S2, is the first crystallographically determined guanidine ligand containing sulfur. It shows two guanidyl groups bridged by a diphenyl­disulfanyl linker with localized C=N bonds. The C—S—S—C group has a folded nonplanar conformation like that found in H2O2 or H2S2, with a torsion angle of 84.65 (10)°. The S—S bond length is 2.0435 (7) A. Molecules are linked by C—H⋯N hydrogen bonds. The crystal studied was an inversion twin with approximately 2:1 components.
(E)-3-(2-Chlorophenyl)-1-(2,4-dichlorophenyl)prop-2-en-1-one

In the title chalcone derivative, C15H9Cl3O, the dihedral angle between the 2-chlorophenyl and 2,4-dichlorophenyl rings is 41.79 (14)°. Weak C—H⋯O and C—H⋯Cl intramolecular interactions involving the enone unit generate S(5) ring motifs. In the crystal structure, the molecules are arranged in a head-to-tail manner along the a axis. These chains are stacked along the b axis.
1-(2,4-Dinitrophenyl)-2-[(E)-(3,4,5-trimethoxybenzylidene)]hydrazine

Molecules of the title compound, C16H16N4O7, are not planar with a dihedral angle of 5.50 (11)° between the substituted benzene rings. The two meta-methoxy groups of the 3,4,5-trimethoxybenzene moiety lie in the plane of the attached ring [Cmethyl–O–C–C torsion angles −0.1 (4)° and −3.7 (3)°] while the para-methoxy substituent lies out of the plane [Cmethyl—O—C—C, −86.0 (3)°]. An intramolecular N—H⋯O hydrogen bond involving the 2-nitro substituent generates an S(6) ring motif. In the crystal structure, molecules are linked by weak C—H⋯O interactions into screw chains, that are arranged into a sheet parallel to the bc plane. These sheets are connected by π–π stacking interactions between the nitro and methoxy substituted aromatic rings with a centroid–centroid separation of 3.9420 (13) Å. C—H⋯π contacts further stabilize the two-dimensional network.
DEFINITIONS OF HEALTH LITERACY AND NUMERACY AND THEIR RELEVANCE FOR PATIENT-PHYSICIAN COMMUNICATION AND TREATMENT DECISION MAKING IN THE MEDICAL ENCOUNTER

Efforts by policymakers to involve patients in treatment decision making are increasing worldwide. Some of these efforts must accommodate patients with different levels of health literacy, but do not specify if numeracy is part of health literacy. This research asked, How are health literacy and numeracy defined in the academic literature and what empirical relationship(s) do they have with the three stages of the treatment decision making process? I conducted a systematic review and two scoping reviews. In the systematic review, I identify definitions of health literacy used in the academic literature and interpretations possible for the most commonly used definitions. In the first scoping review, I map the empirical relationships between health literacy and the three stages of treatment decision making (information exchange, deliberation, and deciding on the treatment to implement). In the second scoping review, I map the empirical relationships between numeracy and the three stages of treatment decision making, and examine if, and how, numeracy has been mentioned in relation to health literacy. The systematic review identified 250 different definitions of health literacy and found the most commonly used definitions open to differing interpretations. The scoping reviews revealed a lack of: (1) agreement over the definition, measurement, and handling of health literacy and numeracy in studies, and (2) overlap in the relationship(s)
(Z)-3-(3,4-Dimethoxybenzylidene)-2,3-dihydro-1,5-benzothiazepin-4(5H)-one

In the title compound, C18H17NO3S, the seven-membered thiazepine ring adopts a slightly distorted sofa conformation. The dihedral angle between the mean plane of the benzothiazepine ring system and the benzene ring is 5.9 (1)°. The molecular conformation is stabilized by an intramolecular C—H⋯S hydrogen bond, which generates an S(7) ring motif. In the crystal, N—H⋯O and C—H⋯O hydrogen bonds link inversion-related molecules into dimers, incorporating R 1 2(6) and R 2 2(8) ring motifs; the acceptor O atom is bifurcated. These dimers are further linked by C—H⋯O hydrogen bonds, forming supramolecular tapes running along the a axis. These are connected into the three-dimensional architecture by C—H⋯π interactions.
4‐(Benzylideneamino)‐3‐(2‐pyridyl)‐1H‐1,2,4‐triazole‐5(4H)‐thione

The title compound, C14H11N5S, was prepared by the reaction of 4-amino-5-(3-pyrid­yl)-1H-1,2,4-triazole-5(4H)-thione and benzaldehyde with ethanol at room temperature. The dihedral angles formed by the benzene and pyridine rings with the triazole ring are 46.2 (1) and 35.1 (2)°. There are weak inter- and intra­molecular hydrogen bonds in the crystal structure.
6-(2,6-Dimethylphenyl)pyrido[2,3-d]pyrimidin-7-amine

In the title compound, C15H14N4, the pyrido[2,3-d]pyrimidine system is almost ideally planar (r.m.s. deviation 0.028 Å) with its mean plane almost orthogonal to the 2,6-dimethylphenyl plane. The dihedral angle formed by these planes [87.3 (2)°] is close to the predicted value (89.7°) obtained by molecular-mechanics force-field calculations. Only one of the two active amine H atoms participates in hydrogen bonding, which links molecules into centrosymmetric dimers.
8-Phenyl-10-oxa-8-azatricyclo[4.3.0.12,5]decane-7,9-dione

The reaction of aniline with norcantharidin produced the imide title compound, C14H13NO3, which shows no significant hydrogen bonds in the crystal structure. The dihedral angle between the phenyl and pyrrolidine rings is 48.48 (6)°.
Antimicrobial activity and suitability of 2-hydroxyisocaproic acid for the treatment of root canal infections

Microbial infection in dental root canal induces an inflammatory reaction called apical periodontitis. In post-treament disease, Enterococcus faecalis is the most commonly found organism, which may survive well in root canal despite calcium hydroxide paste medication. In these cases, effective irrigation or repeated chlorhexidine medication are recommended. New medications with long-lasting antimicrobial activity are needed for the treatment of persistent root canal infections. 2-hydroxyisocaproic acid (HICA) is a protein fermentation product of lactobacilli and few other bacterial or fungal species express enzymes required for its metabolism. However, mammalian cells can metabolise it and use it for protein production. It is known to be well-tolerated by humans and have anti-inflammatory properties as well. Therefore, the hypothesis was that it affects microbe-specific metabolic pathways and have potential as a novel antimicrobial agent. The aim of this study was to evaluate the antibacterial and antifungal spectrum of HICA using in vitro microdilution methods for susceptibility testing and an ex vivo extracted tooth root canal infection-model. The impact of dentine on the antimicrobial activity of HICA was also evaluated. The results showed that HICA has broad-spectrum bactericidal activity for gram-positive and gram-negative organisms. It is also fungicidal for several fungal species and it is only marginally inactivated by clinically-relevant concentrations of dentine. It is at least as active against E. faecalis as presently-used interappointment medications in infected root canals after a seven-day incubation ex vivo. Since HICA has a broad-spectrum and long-term antimicrobial activity as well as an anti-inflammatory effect, it may be a useful new agent for clinical endodontology. However, controlled clinical studies are needed for evaluation of the efficacy of HICA in clinical conditions.
Development and application of statistical methods for prognosis research

A pivotal component of prognosis research is the prediction of future outcome risk. This thesis applies, develops and evaluates novel statistical methods for development and validation of risk prediction (prognostic) models. In the first part, a literature review of published prediction models shows that the Cox model remains the most common approach for developing a model using survival data; however, this avoids modelling the baseline hazard and therefore restricts individualised predictions. Flexible parametric survival models are shown to address this by flexibly modelling the baseline hazard, thereby enabling individualised risk predictions over time. Clinical application reveals discrepant mortality rates for different hip replacement procedures, and identifies common issues when developing models using clinical trial data. In the second part, univariate and multivariate random-effects meta-analyses are proposed to summarise a model’s performance across multiple validation studies. The multivariate approach accounts for correlation in multiple statistics (e.g. C-statistic and calibration slope), and allows joint predictions about expected model performance in applied settings. This allows competing implementation strategies (e.g. regarding baseline hazard choice) to be compared and ranked. A simulation study also provides recommendations for the scales on which to combine performance statistics to best satisfy the between-study normality assumption in random-effects meta-analysis.
Intravenous to Oral Therapy Conversion

1. Explain the rationale behind an intravenous (IV) to oral (PO) therapy conversion program. 2. Differentiate between sequential, switch, and step-down IV to PO conversion therapy. 3. Identify common medications that are included in an IV to PO therapy conversion program. 4. Identify patients who are acceptable candidates to convert from IV to PO therapy. 5. Describe the exclusion criteria that prohibit a conversion from IV to PO therapy. 6. Describe the appropriate steps involved in performing the IV to PO therapy conversion process.
3-(4-Bromophenyl)-1-phenyl-1H-pyrazole-4-carbaldehyde

In the title compound, C16H11BrN2O, the phenyl and chlorobenzene rings are twisted out of the mean plane of the pyrazole ring, forming dihedral angles of 13.70 (10) and 36.48 (10)°, respectively. The carbaldehyde group is also twisted out of the pyrazole plane [the C—C—C—O torsion angle is 7.9 (3)°]. A helical supramolecular chain along the b axis and mediated by C—H⋯O interactions is the most prominent feature of the crystal packing.
ASSESSMENT OF PSYCHOLOGICAL STATES OF CHILDREN WITH CANCER IN A TURKISH SAMPLE

To assess the psychological states of the children with cancer, 18 children with cancer and 24 healthy children were selected. The Children’s Depression Inventory (P aren t Form ) and H acettepe Em otional Adjustm ent Scale were administered to their mothers. Scores on both Children’s Depressiop Inventory (Parent Form ) and Hacettepe Emotional Adjustm ent Scale w ere higher in children with cancer compared to healthy children, but the differences were not statistically significant. Despite having so much stress, the scores indicated no psychological difficulty, which led us to conclude that children with cancer probably used the denial as a healthy defence or that due to their young ages they did not realise the severity o f their condition.
2-(2-Chloro-6,7-dimethylquinolin-3-yl)-2,3-dihydroquinolin-4(1H)-one

In the title molecule, C20H17ClN2O, the dihedral angle between the mean plane of the quinoline ring system and the benzene ring of the dihydroquinolinone moiety is 57.84 (8)°. In the crystal, molecules are linked into centrosymmetric dimers via pairs of intermolecular N—H⋯N hydrogen bonds. These dimers are further stabilized by weak π–π stacking interactions between pyridine rings with a centroid–centroid distance of 3.9414 (12) Å.
(E)-3-Phenyl-3-(3-phenyl-1H-1-pyrazolyl)-2-propenal

In the title compound C18H14N2O, the pendant rings make dihedral angles of 66.1 (1)° and 13.9 (1) with the central ring. In the crystal, two molecules form a cyclic centrosymmetric R 2 2(22) dimer through pairs of C—H⋯O bonds. These dimers are further connected into zigzag chains extending along the b axis through C—H⋯π and C—H⋯O interactions.
14-Hydroxy-11-[(E)-4-methoxybenzylidene]-8-(4-methoxyphenyl)-5-thia-3,13-diazaheptacyclo[13.7.1.19,13.02,9.02,14.03,7.019,23]tetracosa-1(22),15(23),16,18,20-pentaen-10-one

In the title compound, C36H32N2O4S, the piperidine ring adopts a chair conformation, while the five-membered pyrrolidine (with a C atom as the flap atom) and thiazolidine (with the S atom as the flap atom) rings adopt envelope conformations. The naphthalene ring system makes dihedral angles of 18.82 (5) and 40.92 (5)° with the two methoxy-substituted benzene rings. In the crystal, centrosymmetrically-related molecules are linked into dimers via pairs of C—H⋯O and C—H⋯N hydrogen bonds. An intramolecular O—H⋯N hydrogen bond is also observed. The crystal structure is further stabilized by C—H⋯π interactions.
(E)-1-Ferrocenyl-3-(4-methoxyphenyl)prop-2-en-1-one

In the title compound, [Fe(C5H5)(C15H13O2)], a conjugated substituent group bridges a five-membered η5-C5H4 ring and a benzene ring. In the ferrocene unit, the substituted (Cps) and unsubstituted (Cp) cyclopentadienyl rings are eclipsed and almost parallel [Cps—Fe—Cps angle = 176.1 (2)°]. The molecule is linked into an S(5) motif via intramolecular C—H⋯O hydrogen bonds. The molecules are arranged into a three-dimensional framework by five intermolecular C—H⋯O hydrogen bonds and one intermolecular C—H⋯π(Cps) interaction.
ELECTROMYOGRAPHIC ACTIVITY AFTER ANTERIOR CRUCIATE LIGAMENT RECONSTRUCTION DURING NEUROMUSCULAR EXERCISES

The aim of this study was to compare the muscular activity of knee stabilizers in different neuromuscular exercises in individuals with ACL reconstruction and nonlesioned individuals. Eight males submitted to ACL reconstruction and eight nonlesioned males participated. The maximum voluntary isometric contraction (MVIC) of each muscle was used for signal normalization. The electromyographic signal was quantified by the root mean square. The MVIC % between groups was different for extensor muscles of the nonlesioned group, when compared to flexor muscles of the reconstructed group.
Flexural Behavior of Reinforced High-Performance Concrete Beams Made with Steel Slag Coarse Aggregate

In recent years, an emerging technology termed high-performance concrete (HPC) has become popular in construction industry. The constituent materials of HPC depend on the desired characteristics and the availability of suitable local economic alternatives. One of these alternatives is steel slag waste material. It is an industrial by-product waste particles resulted from reinforcing steel bars manufacture, its production is very huge; total quantity produced from all steel rebars manufacture factories in Egypt is nearly million tons/year. HPC made with steel slag aggregate (SSA) is considered as green concrete, using of steel-slag as a coarse aggregate increases the probability of consuming such large accumulations of slag (in HPC industry) which they represent as a waste and polluted material in environment. A total of eight under, balanced and over reinforced concrete beams were fabricated and tested. RC beams were made with HPC having compressive strength of 58.1 and 75.6 MPa and tensile reinforcement ratio in the range of 0.90 to 4.3%. Data presented concentrated on the chemical, physical, and mechanical properties of the used new material (SSA) and the flexural behavior of reinforced high-performance concrete beams made with steel slag coarse aggregate (RHPC-SSA) beams. It was observed that the RHPC-SSA beams can give satisfactory structural performance according to the American and Egyptian Building Codes.
5-[(9H-Fluoren-9-ylidene)methyl]furan-2-carbonitrile

The title compound, C19H11NO, is stabilized by one intramolecular C—H⋯O hydrogen bond. The compound can be synthesized in good yield (49%), by transformation of functional groups [starting with 5-(fluoren-9-ylidenemethyl)furan-2-carbaldehyde]. The flourene and furan ring systems are nearly coplanar, with a dihedral angle of 6.36 (7)°.
1-Isopropylideneamino-1H-tetrazol-5-amine

The molecule of the title compound, C4H8N6, assumes an approximately planar structure, the methyl C atoms and the C atom to which they are bonded being out of the mean tetrazole ring plane by 0.108 and 0.139, and 0.144 Å, respectively. π–π stacking between parallel tetrazole rings [centroid–centroid distance = 3.4663 (11) Å] is observed in the crystal structure. Intermolecular N—H⋯N hydrogen bonding further helps to stabilize the crystal structure.
(2E,6E)-2,6-Bis(4-methylbenzylidene)cyclohex-3-en-1-one

The title compound, C22H20O, shows an approximately planar cyclohexenone ring [maximum deviation = 0.069 (4) Å], with a disordered position of the C=C bond [ratio = 0.71 (2)/0.29 (2)]. The benzene rings of the 4-methylbenzylidene units, attached in the 2- and 6-positions to the cyclohexenone ring, are rotated in the same direction by 28.6 (4) and 22.4 (4)°, with respect to the mean plane of the cyclohexenone ring [fraction 0.71 (2); maximum deviation = 0.06 (3) Å]. In the crystal, molecules are packed in the manner of a distorted hexagonal rod packing with their long axes all aligned along [201]. A number of C—H⋯π interactions stablize the crystal structure.
EFFECT OF NUTRITIONAL EDUCATION BASED ON HBM MODEL ON ANEMIA IN GOLESTAN GIRL GUIDANCE SCHOOL STUDENTS

Background : Iron deficiency is one of the most important cause of anemia , the aim of this study was designed to investigate the effect of health education based on HBM model on knowledge , attitude and practice of Gorgan guidance school students about anemia. Methods : A quasi experimental study was performed on 400 students of grade three in guidance school of Gorgan which were selected via cluster and simple random sampling method. Subjects divided into intervention and control groups . Data collection was performed by a questionnaire include 51 questions based on health belief model in prevention of anemia. Analysis was performed by SPSS software and T test and chi- square tests. A p- value less than 0.05 were considered as significant . Results : The difference between knowledge and attitude and practice about anemia before intervention was not statistically significant but after intervention knowledge , attitude and practice of intervention group and control group was significantly deferent . (P < 0.05). The findings show that the mean score of all dimensions ( except perceived benefit and barriers ) of HBM model in intervention group increase after educational intervention compare by control group . Conclusion : This study finding show that education based on HBM model can affect on students knowledge and attitude toward anemia. Therefore we suggest implementing an educational plan for student in large scale about anemia based on HBM model.
Di-μ-chlorido-bis(chlorido{2,2′-[3-(1H-imidazol-4-ylmethyl)-3-azapentane-1,5-diyl]diphthalimide}copper(II))

The centrosymmetric dinuclear CuII complex, [Cu2Cl4(C24H21N5O4)2], was synthesized by the reaction of CuCl2·2H2O with the tripodal ligand 2,2′-[3-(1H-imidazol-4-ylmethyl)-3-azapentane-1,5-diyl]diphthalimide (L). Each of the CuII ions is coordinated by two N atoms from the ligand, two bridging Cl atoms and one terminal Cl atom. The CuII coordination can be best be described as a transition state between four- and five-coordination, since one of the bridging Cl atoms has a much longer Cu—Cl bond distance [2.7069 (13) Å] than the other [2.2630 (12) Å]. In addition, the Cu⋯Cu distance is 3.622 (1) Å. The three-dimensional structrure is generated by N—H⋯O, C—H⋯O and C—H⋯Cl hydrogen bonds and π–π interactions [centroid–centroid distances = 3.658 (4) and 4.020 (4) Å].
Pyrrolo[2,1-c][1,4]benzodiazepine-5,11-dithione

The seven-membered fused-ring in the title compound, C12H12N2S2, adopts a boat conformation (with the two phenylene C atoms representing the stern and the methine C atom the prow). This methine C atom and the tertiary N atom also belong to a five-membered ring, which has an envelope conformation. In the crystal structure, molecules are linked about a center of inversion by pairs of N—H⋯S hydrogen bonds.
2-[4-(2-Methylpropyl)phenyl]-N′-[(E)-1-phenylethylidene]propanehydrazide

In the title compound, C21H26N2O, the dihedral angle between the two aromatic rings is 85.90 (19)°. The propenone–hydrazide unit forms dihedral angles of 21.62 (8) and 72.83 (9)°, respectively, with the terminal and central aromatic rings. The 2-methylpropyl group is disordered over two sites, with occupancies of 0.533 (13) and 0.467 (13). In crystal structure, molecules are linked into centrosymmetric dimers by paired N—H⋯O and C—H⋯O hydrogen bonds. In addition, C—H⋯π interactions are observed.