Miracle-dz/UniFAR-FTUs huggingface dataset:
SKELETAL MUSCLE MITOCHONDRIAL CAPACITY AND MUSCLE-SPECIFIC ENDURANCE IN PERSONS WITH FRIEDREICH’S ATAXIA by HANNAH

PURPOSE: Evaluate skeletal muscle mitochondrial capacity and muscle-specific endurance using noninvasive methods in persons with Friedreich’s Ataxia (FRDA) and able-bodied controls (AB). METHODS: Participants with FRDA (n=16) and AB controls (n=10) were tested (ages 8-55 yrs). Forearm mitochondrial capacity was measured using the rate of recovery of oxygen consumption after electrical stimulation with near-infrared spectroscopy. Mechanomyography was used to assess muscle-specific endurance after electrical stimulation for 3 minutes at 2Hz, 4Hz, and 6Hz sequentially. RESULTS: There was no difference in mitochondrial capacity (FRDA and AB: 1.8 ± 0.3 1/min). Muscle-specific endurance was significantly impaired by 14% in the FRDA participants in comparison to AB controls (p < 0.001). Correlations show a positive, moderate relationship between these two measurements and a negative, moderate relationship with disease severity in the FRDA group. CONCLUSIONS: Impairments in endurance and relationships between disease severity, endurance and mitochondrial capacity suggest that these measurements can be useful to monitor people with FRDA. The ease of testing and noninvasive nature of these methods also make them appropriate for futures studies. INDEX WORDS: NIRS, Friedreich’s Ataxia, mitochondrial capacity, mechanomyography SKELETAL MUSCLE MITOCHONDRIAL CAPACITY AND MUSCLE-SPECIFIC ENDURANCE IN PERSON WITH FRIEDREICH’S ATAXIA
WIDER Working Paper 2023/116 Exploring the network of individuals that influence the media’s inflation message in South Africa

: The main goal of this study—and its potential to add to the policy debate—is to cast light on the network of voices that influence the narrative about inflation and monetary policy in South Africa. To that end, this paper first identifies the main individuals (journalists, domestic policy makers, and financial analysts) that influence the inflation message in the news media. Using social network analysis, graph theory, and opinion leadership techniques, I describe the relationships and identify the most prominent persons in the network. Second, I use textual analysis to compare the inflation narrative of the South African Reserve Bank with that of the financial analysts and the news media. This comparison aims to add information about what these different groups add to the narrative that is developing in the media. The paper finds some nuanced differences in the way the terms inflation and growth are used. The news has a greater focus on how inflation relates to the target. The South African Reserve Bank, in turn, focuses more on the growth outlook compared to the other two fields, while the financial analysts talk more about growth factors from outside of South Africa.
Ductility of RC Columns confined with FRP Sheets

Many existing structures show insufficient seismic capacity, with the lack of members' ductility being a critical factor. Aim is to manage to increase their ductility, through confinement with composite fiber reinforced polymer (FRP) sheets. In the present paper, available analytical procedures of Eurocode 8‐Part 3 (2005) and draft of 2022 and the Greek Code for Structural Interventions (CSI) of 2013 and the revision of 2022 are examined, compared together with an analytical model proposed in the literature. Analytical results of the above procedures are also compared both with available experimental data and with each other and the degree of their reliability is evaluated. The current EC8‐3 (2005), although in many cases converges quite well with the experimental data, unrealistic results are obtained for a large thickness of the confined material. This seems to be corrected in the proposed EC83 revision of 2022. The Greek CSI 2013 adopts a very simple straight‐forward analytical procedure producing the most conservative results, while the revised analytical expressions included in the 2022 version, has a better convergence with the experiments. However, for large thickness of confinement material, the ductility factor values are unrealistically high. The model proposed in the literature has the advantage of correcting the aforementioned unrealistic result.
Opinions on Irrigation Water Management Tools and Alternative Irrigation Sources by Farmers from the Delta Region of Mississippi

Water withdrawals for irrigation at an unsustainable rate resulted in a decline in the groundwater levels in the Mississippi River Valley Alluvial Aquifer (MRVAA) in the central southern USA. This drawdown of groundwater threatens agricultural production in the Mississippi Delta, an important agricultural region in the state of Mississippi, USA. Effective and efficient use of available resources is important to sustain and enhance agricultural productivity in this area. This study assessed the opinions of farmers on water conservation management practices and technologies that improve irrigation management and save water in the Mississippi Delta region based on data collected in an irrigation survey conducted in 2012. Most landowners believed that water conservation practices were effective in reducing irrigation water use without reducing maximum crop yields and have a positive return on investment. Land forming, tailwater recovery system, on‐farm storage, instream weirs to pond surface water, computerized hole selection for furrow irrigation, short irrigation runs, and irrigation scheduling were considered efficient water conservation technologies by landowners. Perceptions about use of different practices also depend upon the crops produced by the respondents. About 20 to 24% and 14.9 to 86% of survey respondents thought that on‐farm storage and center pivot, respectively, were inefficient water conservation practices for irrigating crops in the Mississippi Delta. The adoption of these practices may be increased if the landowners know the economic returns of implementing them.
The Role of Nonverbal Communication in Asynchronous Talk Channels

With the increased adoption of online learning (even greater as a result of the COVID-19 pandemic), online asynchronous discussions have become a mainstay of many online learning platforms. As teachers struggle to communicate and connect with students due to the forced transition online, we can better appreciate the differences between traditional nonverbal communication in a face-to-face environment and that of online nonverbal communication. Because digital literacy underpins the whole online learning experience, and because nonverbal communication (NVC) cues such as body language and paralanguage are not visible in asynchronous text-based online learning, this paper presents the relationship (if any) between electronic nonverbal communication (eNVC) and teaching/social presences and digital literacy, as well as its role in student motivation and engagement. A correlational study was conducted using surveys to gather data from 88 Level 5 Business Area students. The data was analysed using a Pearson’s correlation analysis. The study has found that there is a correlation between eNVC and the social/teaching presence and digital literacy in the asynchronous online discussions, and that eNVC is related to teaching and social presences, but not to digital literacy.
Academic Self Awareness, Self-Regulation and Academic Burnout among College Students

This study aims to describe the correlation of academic self awareness and self regulation with academic burnout during online lecture among students in Universitas Negeri Yogyakarta (UNY). This correlational research used the descriptive-quantitative approach and the technique in collecting the data was carried out using the questionnaries distributed to the students in UNY. The population in this study was all students in UNY consisting of seven faculties. Meanwhile the sampling was conducted by means of random sampling method. The results of this study showed that: (1) there was a negative and significant correlation between academic self-awareness and academic burn out among the students of UNY with the significant values of 0,000 and the correlation value of -0,75%, (2) there was a negative and significant correlation between self-regulation and academic burn out among the students of UNY with the significant value of 0,000 and the correlation value of -5,19 and (3) there was a significant correlation of academic self-awareness and self-regulation with the academic burnout simultaneously with the significance value of 0,000 and the correlation value of 41,1%.
Dentition of Early Eocene Pakicetus (Mammalia, Cetacea)

Thirty deciduous and permanent teeth of Pakicetus inachus are described from Chorlakki in Palustan. Geological sequence stratigraphy indicates that Pakicetus is latest early Eocene (latest Ypresian) in age. Incisors of Pakicetus are simple high-crowned sharply-pointed teeth. The upper canine may have been double-rooted. Lower canines vary in size and may have been dimorphic. Premolars have simple narrow crowns with coarse serrations on some anterior and posterior crests. Upper molars retain three roots and distinct protocones. ~ o w e r molars have simple pyramidal trigonids and narrow trenchant talonids. These teeth are combined in a model based on the type braincase-basicranium showing that all represent a single species. Pakicerus inachus may prove to be a junior synonym of P. attocki when the latter is better known, but restudy of contemporary Ichthyolestes and Gandakasia confirms that these genera are distinct. The three early Eocene genera are placed in a new subfamily Pakicetinae of the archaeocete family Protocetidae. Teeth of Pakicetus have several distinctively archaeocete characteristics. Upper and lower cheek teeth have wear facets on apices of pointed cusps indicating that the lower jaw was retracted when food was punctured. Buccal phase shearing and lingual phase grinding wear facets are also mesent. Deciduous teeth at Chorlakki indicate that iuveniles and adults were present in approximately equal proportions, suggesting that juveniles, like adults, spent a significant amount of time on land.
Title: Control of polyunsaturated fatty acids desaturation by Sting regulates inflammatory responses

Affiliations: 1 Institut de Génétique Humaine, CNRS, Université de Montpellier, Molecular Basis of Inflammation Laboratory, Montpellier, France 2 Department of Biomedicine, University of Aarhus, Aarhus, Denmark 3 Tumor Microenvironment Laboratory, Institut de Recherche en Cancérologie de Montpellier, Université de Montpellier, INSERM U1194, 34000 Montpellier, France 4 Platform for Translational Oncometabolomics, Biocampus, CNRS, INSERM, Université de Montpellier, Montpellier, France. 5 Azelead, 377 rue du Pr. Blayac, 34080 Montpellier 6 Center for Immunology and Microbial Disease, Albany Medical College, Albany, NY 12208 7 Institut de Génomique Fonctionnelle (IGF), University Montpellier, CNRS, INSERM, 34094 Montpellier, France 8 Laboratory of Genetics, Department of Biotechnology, School of Applied Biology and Biotechnology, Agricultural University of Athens, 75 Iera Odos, 11855 Athens, Greece 9 Division of Endocrinology and Metabolism, Center of Clinical, Experimental Surgery and Translational Research, Biomedical Research Foundation of the Academy of Athens, 11527 Athens, Greece 10 University Research Institute of Maternal and Child Health & Precision Medicine, Medical School, National and Kapodistrian University of Athens, 11527 Athens, Greece
A high-order well-balanced discontinuous Galerkin method for hyperbolic balance laws based on the Gauss-Lobatto quadrature rules

In this paper, we develop a high-order well-balanced discontinuous Galerkin method for hyperbolic balance laws based on the Gauss-Lobatto quadrature rules. Important applications of the method include preserving the non-hydrostatic equilibria of shallow water equations with non-ﬂat bottom topography and Euler equations in gravitational ﬁelds. The well-balanced property is achieved through two essential components. First, the source term is reformulated in a ﬂux-gradient form in the local reference equilibrium state to mimic the true ﬂux gradient in the balance laws. Consequently, the source term integral is discretized using the same approach as the ﬂux integral at Gauss-Lobatto quadrature points, ensuring that the source term is exactly balanced by the ﬂux in equilibrium states. Our method diﬀers from existing well-balanced DG methods for shallow water equations with non-hydrostatic equilibria, particularly in the aspect that it does not require the decomposition of the source term integral. The eﬀectiveness of our method is demonstrated through ample numerical tests.
Concentration and purification of lycopene from watermelon by crossflow microfiltration

The aim of the study was to evaluate a new process based on crossflow microfiltration for concentration and partial purification of lycopene from watermelon. The process included sequentially juice extraction, enzymatic liquefaction, crossflow microfiltration and centrifugation. Different technological schemes were compared including or not a diafiltration step in order to remove soluble solids and increase lycopene purity. Microfiltration was performed at 50-60 °C using alumina tubular membranes with average pore diameter from 0.2 to 1.4  m and varying the transmembrane pressure from 0.5 to 2.0 bar. Using the best operating conditions at the crossflow microfiltration step, permeate flux was close to 110 L.h -1 . m -2 and lycopene concentration was increased 11 times in the retentate. Centrifugation at 10,000 g
Among Adult with Asthma According

18 Objectives: Annual influenza vaccinations are recommended for patients with asthma to prevent 19 against seasonal influenza and influenza-triggered asthma exacerbations. However, there is 20 conflicting data as to the benefit of the influenza vaccine on the frequency of asthma exacerbations. 21 Therefore, this study aimed to assess the effectiveness of the influenza vaccine in terms of reducing 22 the frequency of asthma-related exacerbations and upper respiratory tract infections among adult 23 patients with asthma. Methods: This retrospective cohort study was performed from January to 24 December 2018 in Muscat Governorate, Oman. A total of 466 patients attending nine randomly 25 selected primary health centres in Muscat Governorate were enrolled in the study and followed-26 up for one year post-vaccination. Results: Most patients were female (70.6%) and had moderate-27 persistent asthma (42.9%). Overall, there were 203 patients (43.6%) in the vaccinated group and 28 263 (56.4%) in the non-vaccinated group. A proportion of patients in each group had allergic 29 rhinitis (28.6% and 25.5%, respectively). The frequency of upper respiratory tract infections over 30
Public Perception of Tidal Flooding Hazards on Bonny Island, Rivers State; Nigeria

International research efforts by organizations such as IPCC have revealed past trend of global warming and its future. Based on these estimates, there is justifiable expectation that climate change and sea -level rise could cause a wide range of impacts on coastal zones; some of the typical impacts identified are coastal erosion/ increased flood risk, and impacts on infrastructure. The current study analysed public perceptions of tidal flood hazards on Bonny Island, Rivers State; Nigeria. The focus of the study was to identify the most vulnerable areas on the Island to the t idal inundation as well as assess the local community adaptive capacity to the t idal s urge. Based on a recognizance survey, we ad ministered 270 questionnaires to 15 identified commun ities on the Island that constantly experience tidal floods. Results from the study showed that nearly two-third of the respondents (67.6%) in our study area had good knowledge of the causes, time of occurrence and impact of tidal flood on Bonny Island; that the flood coincides with the spring tides during the raining season which is responsible for its severity occasioned by the building of shanty-type houses within the waterfront and the swamp area resulting in flood pondages that can last for several days ; The time it takes the floodwater to totally recede accord ing to 77% of the people is 12hrs 45mins. Loss of life, household property, business time, sicknesses resulting fro m flood ponds that breed diseases vectors etc are some of the impacts reported by the people. The study also showed that there are no effective mit igation and adaptation strategy put in p lace in the event of a catastrophic ocean surge. No ea rly warning, no co mmunity education as a result respondents show a great level of indifference to the impact caused by the flood by their attitude and lack preparedness.
On optimization of calibrations of a distributed hydrological model with spatially distributed information on snow

Abstract. In northern cold-temperate countries, a large portion of annual streamflow is produced by spring snowmelt, which often triggers floods. It is important to have spatial information about snow variables such as snow water equivalent (SWE), which can be incorporated into hydrological models, making them more efficient tools for improved decision-making. The present research implements a unique spatial pattern metric in a multi-objective framework for calibration of hydrological models and attempts to determine whether raw SNODAS (SNOw Data Assimilation System) data can be utilized for hydrological model calibration. The spatial efficiency (SPAEF) metric is explored for spatially calibrating SWE. Different calibration experiments are performed combining Nash–Sutcliffe efficiency (NSE) for streamflow and root-mean-square error (RMSE) and SPAEF for SWE, using the Dynamically Dimensioned Search (DDS) and Pareto Archived Dynamically Dimensioned Search multi-objective optimization (PADDS) algorithms. Results of the study demonstrate that multi-objective calibration outperforms sequential calibration in terms of model performance (SWE and discharge simulations). Traditional model calibration involving only streamflow produced slightly higher NSE values; however, the spatial distribution of SWE could not be adequately maintained. This study indicates that utilizing SPAEF for spatial calibration of snow parameters improved streamflow prediction compared to the conventional practice of using RMSE for calibration. SPAEF is further implied to be a more effective metric than RMSE for both sequential and multi-objective calibration. During validation, the calibration experiment incorporating multi-objective SPAEF exhibits enhanced performance in terms of NSE and Kling–Gupta efficiency (KGE) compared to calibration experiment solely based on NSE. This observation supports the notion that incorporating SPAEF computed on raw SNODAS data within the calibration framework results in a more robust hydrological model. The novelty of this study is the implementation of SPAEF with respect to spatially distributed SWE for calibrating a distributed hydrological model.
Social Capital, Geography, and Survival: Gujarati Immigrant Entrepreneurs in the U.S. Lodging Industry

Immigrant entrepreneurs often rely on their groups local social capital in their new home market to establish and maintain their businesses. In particular, immigrant entrepreneurs with few resources of their own receive help from those possessing more resources. Supporting these arguments using the empirical setting of Gujarati immigrant entrepreneurs in the lodging industry, we find that the likelihood of survival of an immigrant entrepreneurs hotel increases when surrounded by higher counts of branded hotels (representing high-resource establishments) owned by individuals from their ethnic group but is unaffected by unbranded motels (representing low-resource establishments) owned by members of their ethnic group or by branded hotels owned by individuals from other ethnic groups. These results isolate and reinforce the importance of social capital not only for immigrant entrepreneurs but also more generally for any entrepreneurs belonging to ethnic, professional, religious, or social groups.
Subalklaine Volcanism in the Eastern Basin and Range Province: Examples from the Miocene McCullough Range Volcanic Field and the Pliocene to Holocene Black Rock Desert Volcanic Field

iii ACKNOWLEDGEMENTS.v DEDICATION. x LIST OF TABLES . xv LIST OF FIGURES.xviii CHAPTER ONE: DISSERTATION OVERVIEW.1 CHAPTER TWO: SUBALKALINE VOLCANISM IN THE BLACK ROCK DESERT AND MARKAGUNT PLATEAU VOLCANIC FIELDS OF SOUTHCENTRAL UTAH.7 ABSTRACT.7. 7 INTRODUCTION . 8 GEOLOGIC BACKGROUND. 11 Markagunt Plateau Volcanic Field.11 Black Rock Desert Volcanic Field . 20 DISCUSSION.30 Comparison of Markagunt Plateau and Black Rock Desert Volcanic Fields.30 Source of Basalts from the Markagunt Plateau and Black Rock Desert Volcanic Fields.31 Source of Calc-Alkaline Intermediate and Silicic Rocks.33 Source of Tholeiitic Rocks.34 CONCLUSIONS.34 ACKNOWLEDGEMENTS.35 TABLES AND FIGURES.36 CHAPTER THREE: THE 2.7 – 2.1 MA TWIN PEAKS CALDERA: STRATIGRAPHY AND PETROGENESIS . 49 ABSTRACT.49. 49 xi
HIV-Hypertension Comorbidity, Associated Factors and Treatment Option Among HIV Patients Attending Katsina General Hospital, Katsina State Nigeria

People living with human immunodeficiency virus (HIV) are facing an increased burden of non-communicable diseases (NCDs) comorbidity. There is however, paucity of information on the magnitude of HIV-hypertension comorbidity, its associated factors, and how the health system responds to the burden in Nigeria. This study aimed to determine the magnitude of comorbidity HIV and hypertension and associated factors among HIV-positive adults receiving antiretroviral therapy (ART) in Katsina General Hospital, Katsina. Two hundred (200) HIV infected adults (aged ≥ 18) who had been on antiretroviral therapy for at least six months Katsina General Hospital, Katsina were recruited. Participants’ demographics, HIV characteristics, the presence of non-communicable diseases via self-report, from clinic folders and from measurement of their blood pressure on the day of interview and serum lipid profile, were evaluated. The magnitude of HIV and hypertension comorbidity was 28.5%. Old age, higher BMI, higher viral load, alcohol and duration on antiretroviral therapy were found to be factors associated with development of hypertension among HIV-positive adults. The prevalence of hypertension measured on the day of interview was greater than that found on self-report or reported in the clinic folder. Regular screening for the incidences of hypertension, addressing modifiable risk factors, and providing integrated care in the center would help improve the quality of life of comorbid patients.
Technical Update: Preimplantation Genetic Diagnosis and Screening

This document reflects emerging clinical and scientific advances on the date issued and is subject to change. The information should not be construed as dictating an exclusive course of treatment or procedure to be followed. Local institutions can dictate amendments to these opinions. They should be well documented if modified at the local level. None of these contents may be reproduced in any form without prior written permission of the SOGC. This technical update has been prepared by the Genetics Committee and approved by the Executive and Board of the Society of Obstetricians and Gynaecologists of Canada.