Miracle-dz/UniFAR-FTUs huggingface dataset:
The electrocardiogram of the conscious Chinese goose (Anser cygnoides)

This study was carried out on 24 healthy adult Chinese goose ( Anser cygnoides ) to determine normal electrocardiographic values and patterns in standard bipolar and augmented bipolar limb leads. The study between males and females was also performed to investigate changes in the electrocardiographic patterns related to sex. A regular sinus rhythm was observed in all birds. There was no significant difference between male and female geese except for PR interval, therefore, all data was pooled. All waves in lead I had very low amplitude or almost isoelectric. The P waves, in other leads, were mainly positive in lead II, III and aVF, negative in lead aVR and biphasic in lead aVL. The all waveforms of the QRS complexes (approx. -0.90 mV and 0.03 seconds in lead II) were rS in lead II, III and aVF, and qR in lead aVR and aVL. The T waves (approx. 0.31 mV and 0.06 seconds in lead II) were totally positive in lead II, III and aVF, and negative in aVR and aVL. The majority of birds showed a ST slurring and slightly elevated ST segment in lead II. Heart rates were 142 ± 25 (Mean ± SD) beats per minute and mean electrical axes were -90.88±4.57  in geese. This study provides electrocardiographic data for Chinese goose, which can be used for clinical
Phosphatidic Acid Interacts with a Myeloblastosis Transcription and Regulates Its Nuclear Localization and Function in Arabidopsis

Phosphatidic acid (PA) has emerged as a class of cellular mediators involved in various cellular and physiological processes, but little is known about its mechanism of action. Here we show that PA interacts with WEREWOLF (WER), a R2R3 MYB transcription factor involved in root hair formation. The PA-interacting region is con ﬁ ned to the end of the R2 subdomain. The ablation of the PA binding motif has no effect on WER binding to DNA, but abolishes its nuclear localization and its function in regulating epidermal cell fate. Inhibition of PA production by phospholipase D z also suppresses WER ’ s nuclear localization, root hair formation, and elongation. These results suggest a role for PA in promoting protein nuclear localization.
Matching e¢ ciency and business cycle (cid:135)uctuations (cid:3)

A large decline in the e¢ ciency of the US labor market in matching unemployed workers and vacant jobs has been documented during the Great Recession. We use a simple New Keynesian model with search and matching frictions in the labor market to study the macroeconomic implications of matching e¢ ciency shocks. We show that the propagation of these disturbances and their importance for business cycle (cid:135)uctuations depend crucially on the form of hiring costs and on the presence of nominal rigidities. (cid:3) The views expressed in this paper do not necessarily re(cid:135)ect the views of Norges Bank and the Reserve Bank of New Zealand. For their useful comments, we thank Regis Barnichon, Larry Christiano, Marco Del Negro, Nicolas Jacquet, Alejandro Justiniano, Tim Kam, Fran(cid:231)ois Langot, Ellen McGrattan, Federico Ravenna, Anders Vredin, Jake Wong and seminar participants at the National Bank of Serbia, University of Adelaide, Deutsche Bundesbank, GAINS at the University of Maine, and at various conferences.
A Meta‑Analysis of Line Bisection and Landmark Task Performance in Older Adults

Young adults exhibit a small asymmetry of visuospatial attention that favours the left side of space relative to the right ( pseudoneglect ). However, it remains unclear whether this leftward bias is maintained, eliminated or shifted rightward in older age. Here we present two meta-analyses that aimed to identify whether adults aged ≥50 years old display a group-level spatial attention bias, as indexed by the line bisection and the landmark tasks. A total of 69 datasets from 65 studies, involving 1654 participants, were analysed. In the meta-analysis of the line bisection task ( n = 63), no bias was identified for studies where the mean age was ≥50, but there was a clear leftward bias in a subset where all individual participants were aged ≥50. There was no moderating effect of the participant’s age or sex, line length, line position, nor the presence of left or right cues. There was a small publication bias in favour of reporting rightward biases. Of note, biases were slightly more leftward in studies where participants had been recruited as part of a stand-alone older group, compared to studies where participants were recruited as controls for a clinical study. Similarly, no spatial bias was observed in the meta-analysis of the landmark task, although the number of studies included was small ( n = 6). Overall, these results indicate that over 50s maintain a group-level leftward bias on the line bisection task, but more studies are needed to determine whether this bias can be modulated by stimulus- or state-dependent factors.
Chronic Viral Infections Responses During Acute, Protracted, and Maintenance, Loss, and Resurgence of T Cell

The acute phase of many viral infections is associated with the induction of a pronounced CD8 T cell response which plays a principle role in clearing the infection. By contrast, certain infections are not as readily controlled. In this study, we have used the well-deﬁned system of lymphocytic choriomeningitis virus (LCMV) infection of mice to determine quantitative and qualitative changes in virus-speciﬁc CD8 T cell responses that rapidly resolve acute infections, more slowly control protracted infections, or fail to clear chronic infections. Acute LCMV infection elicits potent, functional, multi-epitope-speciﬁc CD8 T cell responses. Virus-speciﬁc CD8 T cells also expand, albeit to a lesser extent, during protracted LCMV infection. Under these conditions, there is a progressive diminution in the capacity to produce IL-2, TNF- (cid:1) , and IFN- (cid:2) . Changes in cytotoxic activities are also detectable but differ depending upon the speciﬁcity of the responding cells. As the infection is slowly resolved, a resurgence of cytokine production by virus-speciﬁc CD8 T cells is observed. CD4-deﬁcient mice cannot control infection with certain strains of LCMV, but do mount multi-epitope-speciﬁc CD8 T cell responses that also lose effector capabilities; however, they are not maintained indeﬁnitely in an unresponsive state as these cells become deleted over time. Overall, our ﬁndings suggest that constant high viral loads result in the progressive diminution of T cell effector functions and subsequent physical loss of the responding cells, whereas if the viral load is brought under control a partial restoration of CD8 T cell functions can occur. The Journal of Immunology, 2004, 172: 4204–4214.
DYNAMICS FOR THE 3D INCOMPRESSIBLE NAVIER-STOKES EQUATIONS WITH DOUBLE TIME DELAYS AND DAMPING

This paper is concerned with the tempered pullback attractors for 3D incompressible Navier-Stokes model with a double time-delays and a damp- ing term. The delays are in the convective term and external force, which orig-inate from the control in engineer and application. Based on the existence of weak and strong solutions for three dimensional hydrodynamical model with subcritical nonlinearity, we proved the existence of minimal family for pull- back attractors with respect to tempered universes for the non-autonomous dynamical systems.
TRAPPING YELLOWJACKETS (HYMENOPTERA: VESPIDAE) WITH HEPTYL BUTYRATE EMITTED FROM CONTROLLED-RELEASE DISPENSERS

A Numbers of workers of Vespula pensylvanica (Saussure) (western yellowjacket) and V. atro- pilosa (Sladen) trapped with heptyl butyrate in Washington increased with greater release of the attractant from vial dispensers, up to an estimated 2.3 milligrams heptyl butyrate per hour. Vespula germanica (F.) (German yellowjacket) workers were also captured in signiﬁcant numbers, and numbers of workers captured increased with increased release of heptyl butyrate, up to an estimated 1.4 milligrams per hour. Numbers of workers of Vespula squamosa (Drury) trapped with heptyl butyrate in Oklahoma increased with increased release of heptyl butyrate from dispensers, up to an estimated 3.3 milligrams per hour. Vial dispensers, with holes of 6, 12, 22, and 33 mm diameter in the vial lid, lost 0.42, 1.4, 2.3, and 3.3 milli- grams of heptyl butyrate per hour in the laboratory and these rates changed little over a period of 4 weeks, indicating close to a zero order rate of release pattern. Rates of loss of 2 ml heptyl butyrate applied to a cotton ball decreased with exposure time, from an initial rate of 6.0 milligrams per hour to near zero at 16 days post-treatment. Captures of wasps in traps sold commercially might be improved with the use of a controlled-release dispenser. zero mg/hr by day 16. Rate of loss of heptyl bu- tyrate from exposed cotton balls was related to dispenser age (r 2 = 0.93, df = 9, p < 0.01). These results provide conclusive experimental evidence of worker response to heptyl butyrate for the southern yellowjacket V. squamosa and the German yellowjacket V. germanica . Vespula squamosa provide of long-term sustained release of heptyl butyrate optimized release rate. An optimum release rate was determined for butyrate an attractant for trapping V. pensylvanica as well as V. atropilosa . Laboratory indicated release rates (weight losses) of 2.3 and 3.3 milligrams per hour respectively from vials with those hole diameters at laboratory temperatures. The amounts of heptyl butyrate emitted from these vials in the ﬁeld will change with temperature, wind, and other variable environmental parameters, but these results provide a benchmark for comparison to other types of controlled release technologies and materials. The weight losses of vial dispens- ers loaded with heptyl butyrate were steady for 30 days for all hole sizes evaluated. Application of heptyl butyrate to a cotton ball (a presently-used commercial application) provided a release rate that was high and likely to
Unmet Needs in Understanding Lipoprotein(a) Pathophysiology: NHLBI Working Group Recommendations to Reduce Risk of Cardiovascular Disease and Aortic Stenosis

Pathophysiological, epidemiologic and genetic studies provide strong evidence that Lp(a) is a causal mediator of cardiovascular disease (CVD) and calcific aortic valve disease (CAVD). Specific therapies to address Lp(a)-mediated CVD and CAVD are in clinical development. Due to knowledge gaps, the National Heart, Lung, and Blood Institute (NHLBI) standardized Lp(a) assays and inadequate understanding of the mechanisms underlying current drug therapies on Lp(a) levels. Specific recommendations were provided to facilitate basic, mechanistic, preclinical, and clinical research on Lp(a), foster collaborative research and resource sharing, leverage expertise of different groups and centers with complementary skills, and utilize existing NHLBI resources. Concerted efforts to understand Lp(a) pathophysiology, together with diagnostic and therapeutic advances, are required to reduce Lp(a)-mediated risk of CVD and CAVD.
AN OBSERVATIONAL STUDY ON THE TYPES OF KIDNEY STONES IN CHILDREN OF PUNJAB, PAKISTAN

: Objective: The aim of this study is to find out the frequency of different types of kidney stones in the children having lower than fifteen years of age. Methodology: This is an observational research work. The collection of information and samples of stones carried out from one hundred and forty-five patients admitted in different hospitals of Lahore. Dia-Sys analysis kit of urinary calculi was in utilization for the chemical identification of the stone samples. SPSS V. 16 was in use for the analysis of the gathered information. Results: The average age of the patients was 7.370 ± 4.10 years. The formation of the stones was much common in male gender. The previous history of the family was available in the case of 44.140% children. Most of the (32.40%) kidney stones were available as heterogeneous in their structure. There were complete calcium oxalate kidney stones in only 26.20% structures of stones. Calcium oxalate was also the main ingredient in ninety-eight percent samples of stones, trailed by calcium phosphate in 58.60% samples of stones, ammonium urate presents in 45.50% stone samples & uric acid available in 4.130% patients of this research work. Conclusion: Most of the kidney stones were available with heterogeneous structure and the main ingredient in their formation was calcium oxalate. The main indication of the formation of the stones is the past history of the family.
Pneumonia in a Snail Cornu aspersum (Gastropoda, Pulmonata)

The larger part of the shell in a garden snail ( Cornu aspersum ) had been eaten away by mice, thus exposing the lung. This has most probably, affected the main pulmonary blood vessels running over the dorsal surface of the lung. The alveolar walls had atrophied, mimicking alveolar emphysema. Many blood capillaries were open. In consequence blood had floated in the alveolar spaces. Gas exchange was severely hampered. Inflammatory reactions were minimal.
Modern Feedback System: A Survey

- The Feedback given by the stake holders about the current state of performance of any organization is essential for its growth. It provides vital information, which can be used to improve performance. In this way it provides motivation and fuels the continual improvement process. In business, it helps to deliver the best customer experiences. It forms the backbone of success of any institution or individual. It also forms the crust of good supervision in any organization. Feedback system initially started with raising hands, saying yes or no, then it evolved into answering questions through feedback forms, suggestion boxes etc. With the evolution in internet technology, it has now changed into web based, app based feedback systems etc. This paper explains different feedback systems that are currently in use and also explains about advantages and disadvantages of these systems.
C OMMUNICATION BY N URSES IN THE I NTENSIVE C ARE U NIT : Q UALITATIVE A NALYSIS OF D OMAINS OF P ATIENT -C ENTERED C ARE

High-quality communication is a key determinant and facilitator of patient-centered care. Nurses engage in most of the communication with patients and patients’ families in the intensive care unit. Objective To perform a qualitative analysis of nurses’ communications. Methods Ethnographic observations of 315 hours of interactions and 53 semistructured interviews with 33 nurses were conducted in a 26-bed cardiac-medical intensive care unit in an academic hospital and a 26-bed general intensive care unit in a Veterans Affairs hospital in Portland, Oregon. Communication interactions were categorized into 5 domains of patient-centered care. Interviews were analyzed to identify major themes in nurses’ roles and preferences for communicating with patients and patients’ families within the domains. Results Most communication occurred in the domains of biopsychosocial information exchange, patient as person, and clinician as person. Nurses endorsed the importance of the domains of shared power and responsibility and therapeutic alliance but had relatively few communication interactions in these areas. Communication behaviors were strongly influenced by the nurses’ roles as translators of information between physicians and patients and the patients’ families and what the nurses were and were not willing to communicate to patients and patients’ families. Conclusions Critical care, including communication, is a col-laborative effort. Understanding how nurses engage in patient-centered communication in the intensive care unit can guide future interventions to improve patient-centered care. ( American Journal of Critical Care. 2012;21:410-418)
Long-term consumption of high-fat diet impairs motor coordination without affecting the general motor activity

Consumption of affordable food that is rich in fat and carbohydrates has increased over the last few decades. As such, high caloric intake and weight gain contribute to sedentary lifestyle. The aim of this study was to investigate the long-term effect of food reach in fat on motor function and dopaminergic system. In the present study, six-week old male C57bl/6 mice were fed either high-fat diet (HFD) or regular chow diet (RD) for 15 months, followed by estimation of spontaneous locomotor activity, body composition, assessment of metabolic outcomes, and histological examination of dopaminergic neurodegeneration. Although body weight stayed similar in both diet-fed mice, HFD-fed mice had decreased lean tissue mass and increased fat mass. In particular, isolation of fat depots showed that HFD-fed mice had increased brown, retroperitoneal and subcutaneous fat mass, in comparison to WT mice. Reduced lean tissue did not influence the muscle strength as it was shown by grid test. The HFD intake did not affect the spontaneous locomotor activity. However, HFD-fed mice displayed time-dependent reduction in motor coordinative skills measured by rotarod, and this was further confirmed by pole test, stepping test and hind-limb clasping test towards the end of in vivo studies. Reduction in coordinative abilities of HFD-fed mice was accompanied by impaired glucose tolerance test, elevated blood insulin and leptin levels. Histological data showed that HFD consumption did not induce loss of tyrosine hydroxylase (TH)-positive dopamine neurons, nor increased number of activated CD68-positive microglia cells in substantia nigra (SN). Taken together, these data suggest that adiposity and insulin resistance induced with HFD consumption led to reduced motor coordination.
Measuring Knowledge in Computer Network Vocational Training by Monitoring Learning Style Preferences of Students

Learning style preferences play a significant role during the learning and teaching process. Therefore, a multitude of researchers have developed different models to accommodate students’ various learning styles. Those models share the same goal of trying to classify a particular students’ learning style and to provide an overview of better teaching strategies for educators. This paper presents a research study based on a survey that investigates the learning style preferences of computer network vocational senior secondary school students in Yogyakarta Province, Indonesia. This survey uses the Index of Learning Styles (ILS) questionnaire developed by Felder and Solomon. In total, 162 data sets from five different schools in five different areas were collected in order to represent the Yogyakarta Province. The findings from the study show that students participating in computer network vocational training preferred active (82.66%), sensing (67.66%), visual (83.83%), and sequential (52.44%) learning styles. Students most strongly prefer visual and least favor verbal (16.17%). Identifying learning styles can benefit teachers as they customize teaching methods and can maximize the learning and teaching process.
The Interface of Coronary Artery Disease and Depression: Pathophysiology and Diagnosis

Coronary Artery Disease (CAD) and depression are two of the most common human health problems. The association between CAD and depression is suggested to be bidirectional: depression is highly prevalent among patients with CAD and depression behaves as a risk factor for the development of CAD. Both diseases are complex disorders that are influenced by genetic and environmental factors. It has been suggested that depression is associated with both physiological and psychosocial changes that are deleterious to the cardiovascular system; although, the mechanisms underlying this connection remain unclear. There is a large body of literature demonstrating that pro-inflammatory cytokines, endocrine factors, and metabolic markers contribute to the pathophysiology of depressive disorders and antidepressant response. Although, it has been suggested that sex differences in the prevalence of major depression among cardiac patients exist: the prevalence of major depression is approximately two-times greater in women with CAD compared to men, similar to the general population. Depression is under-recognized in CAD patients because healthcare providers rarely use standardized screening instruments. For this reason, its important a systematic screening for depression in all CAD patients. The aim of the present review was to systematically report current evidence on the biological mechanism at the base of depression-CAD relationship and the diagnostic method available in CAD patients.
The Long Run Impacts of Child Health on Parents’ Economic and Mental Wellbeing ∗

How do parents contend with threats to the health and survival of their children? We combine the universe of cancer diagnoses among Danish children with register data for aﬀected and matched unaﬀected families. Parental income declines substantially for 3-4 years following diagnosis, an eﬀect driven by reductions in working hours. Fathers’ incomes recover fully, but mothers’ incomes remain 5% lower 12 years after diagnosis. Both parents increase their use of mental health services. Fertility increases, particularly among families in which the child died. These results demonstrate that even in high-income settings, severe shocks to child health can have long-lasting consequences for family outcomes.
Analyzing Presentation Format for Design Development Stages in Architecture Studio Presentation Format for Design Development Stages in Architecture Studio Presentation Format for Design Development

With the advent and popularization of Computer Aided Design (CAD) tools, students of architecture appear to be gradually losing the art of freehand sketching in developing design design studio schoolmodules especially during the early formative years of the program result is that more students tend to present their design works at the development stages in CAD during crits. format of presentation affects the use of freehand sketching amongst students of architecture; however format of presentation af final juries. from the graduate that are undertaking studio design projects in the State Univ argue that the format of using freehand sketches in design development stagejury than the use of key markers are indicative of of p revealed other issues regarding the effects of the format of presenta were Abstract With the advent and popularization of Computer Aided Design (CAD) tools, students of architecture appear to be gradually losing the art of freehand sketching in developing design concepts, forms and study drawings in the design studio. This is mainly due to the liberaliz schools of architecture regarding the use of CAD in teaching design studio modules especially during the early formative years of the program result is that more students tend to present their design works at the development stages in CAD during crits. Studies have shown that this format of presentation affects the use of freehand sketching amongst students of architecture; however the aim of this study is format of presentation affects the overall design outp final juries. The study is based on a survey of 120 students of architecture from the undergraduate and graduate programmes that are undertaking studio design projects in the Rivers State University argue that the format of using freehand sketches in design development stages lead to all round better design outputs when presented at jury than the use of CAD tools. The results show that whi key markers are indicative of the format of presentation the rest markers show no bearing to the presentation format revealed other issues regarding the effects of the format of presenta were not in the initial study foresights butare worth discussing.