Miracle-dz/UniFAR-FTUs huggingface dataset:
Prospective evaluation of chronic rhinosinusitis with reference to anatomical variation

Background: Rhinosinusitis is one of the commonest sinonasal condition with chronic Rhinosinusitis affecting 10% of population worldwide. Although the diagnosis of chronic rhinosinusitis is clinical, the final diagnosis should be confirmed by objective measures like radiography and nasal endoscopy. Though anatomical variations in sinonasal region are rare, they have significant impact in the causation of sinonasal diseases and pose difficulties during surgery. Methods: This was a prospective study conducted on 60 patients who attended to the Department of ENT and HNS, Konaseema Institute of Medical Science, Amalapuram between December 2017 to July 2019. By considering AAO-HNS criteria patients were selected and subjected to high resolution computerized tomography para nasal sinuses and diagnostic nasal endoscopy. Results: As per study, 60% patients are having deviated nasal septum, followed by aggar nasi in 58.3%, concha bullosa in 26.8%, Haller cells in 11.7%, paradoxical middle turbinate in 11.7%, uncinate pneumatisation in 5%, and onodi cells in 5% of cases. Conclusions: Anatomical variations in sinonasal cavity predispose to chronic rhinosinusitis and hence require correction. Also, detecting these variations preoperatively by computed tomography of paranasal sinus helps in avoiding complications during functional endoscopic sinus surgery.
Education Quality and Teaching Practices

Improving school quality with limited resources is a key issue of policy. This article uses a randomised controlled trial (RCT) to estimate the effectiveness of guided instruction methods as implemented in under-performing schools in Chile. The intervention improved performance substantially, and equally for boys and girls. However, the effect is mainly accounted for by children from relatively higher-income backgrounds. Basing our study on the Classroom Assessment Scoring System (CLASS) instrument, we document that the quality of teacher–student interactions is positively correlated with the performance of low-income students; however, the intervention did not affect these interactions. Guided instruction improves outcomes, but the challenge to reach the most deprived children remains.
Combination Therapy in Moderate to Severe Alzheimer’s Disease - Overview and Discussion Points for the Future

Two effective symptomatic therapies are available for Alzheimer’s disease: the cholinesterase inhibitors (ChEIs) and memantine, an N-methyl-D-aspartate receptor antagonist. Current data demonstrate that combination therapy with memantine and a ChEI produces symptomatic benefits in all domains of AD. The benefits of combination therapy are greater than those of ChEI monotherapy, are sustained long term and appear to increase with time.
Versatile roles for tetraspanin CD53 in the dynamic regulation of lymphocyte signaling

To facilitate the myriad of different (signaling) processes that take place at the plasma membrane, cells depend on a high degree of membrane protein organization. Important mediators of this organization are tetraspanin proteins. Tetraspanins interact laterally amongst themselves and with partner proteins to control the spatial organization of membrane proteins in large networks called the tetraspanin web. The molecular interactions underlying the formation of the tetraspanin web were hitherto mainly described based on their resistance to different detergents, a classification which does not necessarily correlate with functionality in the living cell. To look at these interactions from a more physiological point of view, this review discusses tetraspanin interactions based on their function in the tetraspanin web; 1) intramolecular interactions supporting tetraspanin structure, 2) tetraspanin-tetraspanin interactions supporting web formation, 3) tetraspanin-partner interactions adding functional partners to the web, and 4) cytosolic tetraspanin interactions regulating intracellular signaling. The recent publication of the first full length tetraspanin crystal structure sheds new light on both the intraand intermolecular tetraspanin interactions that shape the tetraspanin web. Furthermore, recent molecular dynamic modeling studies indicate that the binding strength between tetraspanins and between tetraspanins and their partners are the complex sum of both promiscuous and specific interactions. A deeper insight into this complex mixture of interactions is essential to our fundamental understanding of the tetraspanin web and its dynamics which constitute a basic building block of the cell surface.
FACTORS AFFECTING THE DELAY OF COMPANY FINANCIAL STATEMENTS

This study aims to prove the influence of company size and profitability toward timeliness of company's financial statement. The population of this study is mining companies that were listed in Indonesia Stock Exchange (BEI) in 2016 -2018. The method used for determining the sample was purposive sampling method and the number of samples obtained was 36 companies. The results of this study indicate that company size and profitability variables have no effect on timeliness of company's financial statement.
Study of factors affecting maternal and fetal outcome in HIV positive women

Background: HIV virus infection was detected first time in India in Tamil Nadu in April 1986; India has the third largest HIV epidemic in the world. In 2013, HIV prevalence in India was an estimated 0.3 percent. The pregnant women and her unborn child who are HIV reactive are mostly innocent bearers of the brunt of the infection. Mother-to-child transmission of HIV is a major route of new infections in children. Without any intervention, the risk of transmission of HIV from infected pregnant women to her child is estimated to be around 20- 45%. Early diagnosis of children born to HIV positive mother using HIV DNA PCR and treating children who are diagnosed HIV-positive with antiretroviral drugs within their first 12 weeks of life reduces mortality by 75%. Methods: This retrospective data analytic study of HIV positive pregnant women who attended antenatal clinic and delivered at M.Y. Hospital, Indore from January 2011 to December 2013 . For screening of ANC patients ELISA method was used. For the children, HIV DNA was done by sending the dried blood smear on blot paper and was sent to the reference laboratory Kasturba Hospital, Mumbai and used for diagnosis at 6 week and 6 month. Results: Only 50% of HIV positive children were started on ART, 20% died, 20% loss to follow up and 10% were not willing for follow up. Also 30% mothers practiced mixed feeding. Neonatal mortality rate was 54.87 per thousand live births which is more than the seronegative mothers. Conclusions: First HIV DNA testing can be done at 72 hours to detect antenatal HIV transmission. Early testing can pick up these cases early and ensure treatment. Mixed feeding should be strongly discouraged by counseling and modern methods of communication.
A Rare Case of Viagra Induced Toxic Encephalopathy

Viagra is the commercial name of Sildenafil citrate, a selective phosphodiesterase type 5 (PDE-5) inhibitor. It was originally synthesized to treat hypertension and angina pectoris. However, the drug showed little effect on those clinical aspect, and was rather found to be useful for inducing penile erection. After gaining approval from Food and Drug Administration (FDA) 1998, it has been prescribed worldwide to treat male erectile dysfunction. Like many other drugs, sildenafil may cause various kinds of adverse effects. Most commonly reported adverse effects include headache (16%), facial flushing (10%), dyspepsia (7%), nasal congestion (4%), and visual disturbances (3%) (1). Sildenafil may also cause central nervous system (CNS) adverse effects such as dizziness, depression, insomnia, abnormal dreams, somnolence, and nervousness, but these are very rarely identified (1, 2). Here we present a case of toxic encephalopathy induced by sildenafil since there were no reported cases about neuroradiologic findings of Viagra induced toxic encephalopathy.
Effect of Combination of Different Levels of Pruning, Nutrition and Paclobutrazol on Yield and Economics of Mango (Mangifera indica L.) cv. Alphonso

Mango (Mangifera indica L.) is a delicious fruit and member of family Anacardiaceae, in the order Sapindales with chromosomal number 2n=4x=40. It is one of the most important tropical fruit of the world and is the national fruit of India. Mango (Mangifera indica L.) is called ‘the King of fruits’ due to its wide adaptability, delicious taste, excellent flavor, attractive appearance and richness in phytochemical and nutrient (Purseglove, 1972). India has traditionally been the world's largest producer of mangoes and having area International Journal of Current Microbiology and Applied Sciences ISSN: 2319-7706 Volume 8 Number 11 (2019) Journal homepage: http://www.ijcmas. com
Demystifying the concept of offsite manufacturing method

This study aims to develop a more inclusive working definition and a formalised classification system for offsite construction to enable common basis of evaluation and communication. Offsite manufacturing (OSM) is continuously getting recognised as a way to increase efficiency and boost productivity of the construction industry in many countries. However, the knowledge of OSM varies across different countries, construction practices and individual experts thus resulting into major misconceptions. The lack of consensus of what OSM is and what constitutes its methods creates a lot of misunderstanding across Architecture Engineering and Construction (AEC) industry professionals, therefore, inhibiting a global view and understanding for multicultural collaboration. Therefore, there is a need to revisit these issues with the aim to develop a deep understanding of the concepts and ascertain what is deemed inclusive or exclusive. ,A state-of-the-art review and analysis of literature on OSM was conducted to observe trends in OSM definitions and classifications. The paper identifies gaps in existing methods and proposes a future direction. ,Findings suggest that classifications are mostly aimed towards a particular purpose and existing classification system are not robust enough to cover all aspects. Therefore, there is need to extend these classification systems to be fit for various purposes. ,This paper contributes to the body of literature on offsite concepts, definition and classification, and provides knowledge on the broader context on the fundamentals of OSM.
Full Range Leadership, Organizational Culture, and Job Satisfaction as Predictors of Job Performance for Police Investigators

Job performance is important for determining the success of an organization and for achieving their goals. This study focuses on the South Jakarta Metropolitan Police Criminal, which had problems with their investigators’ performance. The purpose of this study was to examine the influence of leadership, organizational culture, job satisfaction, and job performance on Police Investigators of South Jakarta Metropolitan Police CID. A hypothetic model was self-modified on basis of some of previous studies and the initial hypothesis stated that there was a positive influence or correlation of the three variables on the investigator’s job performance. This study used a mix-methods of questionnaire to collect data from overall population of 59 investigators from the South Jakarta Metropolitan Police CID, which was followed by interviews of eight related informants. More significantly, the data obtained were analyzed using structural equation modeling and partial least square software to focused on multi-variant variables. The study results showed that full range leadership, organizational culture, and job satisfaction had a positive and significant influence on investigators’ performance, and full range leadership was the most influencing factor. Keywords—full range leadership, job performance, job satisfaction, organizational culture
Sounds of Green: How Brand Name Sounds Metaphorically Convey Environmental Friendliness

Conveying the environmental friendliness of a product is both crucial and challenging. One efficient way to overcome this challenge is by using brand names as a way to signal environmental friendliness. Linking research in sound symbolism and metaphor cognition, the current research suggests that silent consonants in brand names (e.g., Etopal), compared to voiced consonants (e.g., Edopal), are more effective in conveying environmental friendliness. A series of four studies conducted online and in the field show that brands with silent consonants are perceived as more environmentally friendly than voiced brand names because silent consonants in brand names convey human characteristics that are metaphorically associated with environmental friendliness (e.g., good-heartedness, humility). Marketing implications for green product branding and directions for future research are discussed.
Take it Personally - The Role of Consumers' Perceived Value of Personalization on Cross-Category Use in a Smart Home Ecosystem

The establishment of a smart home ecosystem – an assemblage of smart technologies across segments in private households – generates value for both companies and customers. However, the complexity of a smart home ecosystem based on data sharing and personalization as a necessity for value perception also generates tensions between the value created by data sharing and the value of privacy. Therefore, this study, based on a survey of 1049 consumers, investigates the acceptance and use of smart home devices and smart home ecosystems by observing drivers of personalization, trust, privacy components and technology acceptance. The empirical analyses show that especially consumers’ perceived value from personalization plays a significant role in smart home ecosystem acceptance. This research offers results for theory development and practical implications by extending existing technology acceptance models to ecosystems and by showing the need for a focus on sophisticated personalized applications within a smart home ecosystem.
Who is Not Afraid of Richard Dawkins? Using Google Trends to Assess the Reach of Influential Atheists across Canadian Secular Groups

Google Trends data on search volumes of high profile atheist public figures are used to assess their relative reach among different types of seculars in Canada. The user query data mined from Google Trends are complemented with an extensive set of information extracted from the Canadian General Social Surveys of 2005 to 2016. The analysis shows that the reach of high profile atheists is positively correlated with the presence of strictly-seculars, a proxy for the atheists. The investigation produces no statistically significant correlation between the presence of other types of seculars, namely the unchurched believers and the nominal affiliates, and the search volumes for high profile atheists. This exploratory finding suggests that the influential atheists likely “preach to the choir,” catering to like-minded individuals, at the exclusion of those with relatively close but differing views on religion and spirituality.
Active contraction of the left ventricle with cardiac tissue modelled as a micromorphic medium

Active Contraction of the Left Ventricle with Cardiac Tissue Modelled as a Micromorphic Medium Marina Kamper The myocardium is composed of interconnected cardiac fibres which are responsible for contraction of the heart chambers. There are several challenges related to computational modelling of cardiac muscle tissue. This is due in part to the anisotropic, non-linear and time-dependent behaviour as well as the complex hierarchical material structure of biological tissues. In general, cardiac tissue is treated as a non-linear elastic and incompressible material. Most computational studies employ the theories of classical continuum mechanics to model the passive response of the myocardium and typically assume the myocardium to be either a transversely isotropic material or an orthotropic material. In this study, instead of a classical continuum formulation, we utilise a micromorphic continuum description for cardiac tissue. The use of a micromorphic model is motivated by the complex microstructure and deformations experienced by cardiac fibres during a heartbeat. The micromorphic theory may be viewed as an extension of the classical continuum theory. Within a micromorphic continuum, continuum particles are endowed with extra degrees of freedom by attaching additional vectors, referred to as directors, to the particles. In this study the directors are chosen such that they represent the deformation experienced by the cardiac fibres. In addition to the passive stresses, the myocardium experiences active stresses as a result of the active tension generated by cardiac fibres. The active tension in the heart is taken to be a function of the sarcomere length, intracellular calcium concentration and the time after the onset of contraction. Experimental studies show that the active behaviour of the myocardium is highly dependent on the tissue arrangement in the heart wall. With a classical continuum description, the sarcomere length is usually defined as a function of the stretch in the initial fibre direction. To allow for a more realistic description of the active behaviour, we define the sarcomere orientation, and consequently also the sarcomere stretch, as a function of the director field. Furthermore, we use the director field to describe the direction in which contraction takes place. The intent of this study is to use a micromorphic continuum formulation and an active-stress model to investigate the behaviour of the left ventricular myocardium during a heartbeat. The simulated results presented here correspond well with typical ventricular mechanics observed in clinical experiments. This work demonstrates the potential of a micromorphic formulation for analysing and better understanding ventricular mechanics.
Are current SERVQUAL dimensions applicable for measuring service quality within the Scottish emergency services

Purpose. The purpose of this study is to understand whether the SERVQUAL tool could be applied to measure internal service quality in the Emergency Services and examine what internal customers of this sector view as essential elements of service quality. Methodology. A qualitative approach, focus groups with 8 participants from police and ambulance services, was used to collect data as part of the research. Findings. The findings of this primary research revealed that the concepts of service quality and the internal customer were not widely understood within this sector. The results also indicated that the current dimensions of service quality did capture the essential characteristics of internal service quality within the emergency services with assurance and empathy featuring heavily. Practical Implications. The results indicate that an adapted version of SERVQUAL with additional dimensions of ‘wellbeing; and ‘resourcing’ can be successfully utilised for measuring service quality in the emergency services. Originality/ value. This work adds contribution to existing knowledge in Service Quality research within the emergency services and will be of value to professionals and researchers in this field.
Analysts’ Optimism and Stock Crash Risk

The purpose of this paper is to investigate whether analysts’ optimism affects the stock crash risk. ,The sample covers 49,246 firm-year observations for the period between 1995 and 2015. The authors use OLS regressions with firm and year fixed effects for analyses. ,The study finds that there is a positive association between analysts’ optimism and stock crash risk. Such a positive impact is more pronounced for firms with opaque information environment and for analysts who are considered ex ante credible. ,The results indicate that analysts’ optimism can be an important source of stock crash risk. ,The findings can be useful for informational users of analyst reports. Given that information provided by analysts might have negative consequences, the empirical results can be useful in assessing future stock return behaviors. ,This paper has the potential to shed light on the large literature of crash risk. Prior studies suggest that crash is driven by the agency tension between shareholders and managers. It remains possible that crashes could be caused by overpriced stocks in the absence of bad news hoarding. The paper investigates crash from a perspective, financial analysts, that is underexplored.
An Exploratory Study of Factors Associated with Alcohol and Drug Use Among Latino Adolescents: A Secondary Data Analysis

Latino adolescents in the United States have reported a higher annual prevalence of use of nearly all illegal drugs compared to non-Latino adolescents over the past several years. With the rapid growth of the Latino population in the U.S. there is an increasing need to better understand the factors associated with substance use among adolescents. Learning more about these factors can enhance knowledge surrounding current prevalence rates, inform future research, and support prevention programs designed for Latino adolescents. This exploratory study used secondary data analysis to investigate the difference between Latino and non-Latino adolescents' attitudes, subjective norms, and perceived behavioral control as it relates to alcohol and marijuana use, and the misuse of prescription drugs. Results from this study indicate that attitude, subjective norms, and perceived behavioral control differ between Latino and non-Latino adolescents. Latino adolescents report a higher perceived acceptability of alcohol and marijuana use, and a lower perceived risk of prescription drug misuse as compared to non-Latino adolescents. Measures for subjective norms indicate that, compared to non-Latino peers, Latino adolescents report higher perceptions of family approval for smoking marijuana, as well as higher perceptions of peer approval for misusing prescription drugs and consuming alcohol almost daily. While risk perceptions were low and attitudes toward the use of alcohol, marijuana, and other drugs were more favorable for Latino adolescents as compared to non-Latino adolescents, access to prescription drugs was perceived to be more difficult. In sum, perceived risks and acceptability of illegal drug use, family and peer approval, and access to substances are factors that differ between Latino and non-Latino adolescents, factors that could potentially influence a Latino adolescent's decision to use a substance.