Miracle-dz/UniFAR-FTUs huggingface dataset:
Multichannel Recovery Potential with Activated Autologous Intraovarian Platelet-Rich Plasma and Its Derivatives

Platelet-rich plasma (PRP) is an ‘orthobiologic’ with recognized roles in plastic surgery, musculoskeletal disorders, dentistry, dermatology, and more recently, ‘ovarian rejuvenation’. Intraovarian PRP involves a complex secretome discharged after platelet activation, comprising multiple cytokine mediators delivered surgically to older or inactive ovarian tissue. Loss of oocyte meiotic fidelity and impaired fertilization accompanying advanced maternal age are already managed by IVF, but only with eggs provided by younger donors. However, if the observed effect of rectifying embryo ploidy error can be proven beyond case reports and small series, activated PRP (or its condensed plasma cytokines) would deliver a welcome therapeutic disruption that is difficult to overstate. Because shortcomings in ovarian function are presently addressed mainly by pharmacological approaches (i.e., via recombinant gonadotropins, GnRH analogs, or luteal support), autologous PRP would represent an unusual departure from these interventions. Given the diversity of platelet cargo proteins, the target response of intraovarian PRP is probably not confined to oocytes or follicles. For example, PRP manipulates signal networks driving improved perfusion, HOX regulation, N-glycan post-translational modification, adjustment of voltage-gated ion channels, telomere stabilization, optimization of SIRT3, and ribosome and mitochondria recovery in older oocytes. While multichannel signals operating on various pathways are not unique to reproductive biology, in intraovarian PRP this feature has received little study and may help explain why its standardization has been difficult. Against this background, our report examines the research themes considered most likely to shape clinical practice.
Physical Activity, Sedentary Behavior, and Type 2 Diabetes: Mendelian Randomization Analysis

Abstract Context The causality and pathways of the associations between physical activity and inactivity and the risk of type 2 diabetes remain inconclusive. Objective We conducted an updated mendelian randomization (MR) study to explore the associations of moderate-to-vigorous physical activity (MVPA) and leisure screen time (LST) with type 2 diabetes mellitus (T2DM). Methods Genetic variants strongly associated with MVPA or LST with low linkage disequilibrium were selected as instrumental variables from a genome-wide meta-analysis including more than 600 000 individuals. Summary-level data on T2DM were obtained from the DIAbetes Genetics Replication And Meta-analysis consortium including 898 130 individuals. Data on possible intermediates (adiposity indicators, lean mass, glycemic traits, and inflammatory biomarkers) were extracted from large-scale genome-wide association studies (n = 21 758-681 275). Univariable and multivariable MR analyses were performed to estimate the total and direct effects of MVPA and LST on T2DM. Methylation MR analysis was performed for MVPA in relation to diabetes. Results The odds ratio of T2DM was 0.70 (95% CI, 0.55-0.88; P = .002) per unit increase in the log-odds ratio of having MVPA and 1.45 (95% CI, 1.30-1.62; P = 7.62 × 10−11) per SD increase in genetically predicted LST. These associations attenuated in multivariable MR analyses adjusted for genetically predicted waist-to-hip ratio, body mass index, lean mass, and circulating C-reactive protein. The association between genetically predicted MVPA and T2DM attenuated after adjusting for genetically predicted fasting insulin levels. Two physical activity-related methylation biomarkers (cg17332422 in ADAMTS2 and cg09531019) were associated with the risk of T2DM (P < .05). Conclusion The study suggests causal associations of MVPA and LST with T2DM that appear to be mediated by obesity, lean mass, and chronic low-grade inflammation.
The Impact of the Negotiator’s Personality on the Negotiation process and Outcome Submitted By

This research examines the effect a negotiator’s personality has on the negotiation process and outcome. Negotiation directly influences an organization’s profit. An organization’s profitability would increase if its buyers buy cost effectively and its sales team sells with a high profit margin. Hence, it is essential to hire the right people and to invest in an effective training; otherwise, the organization would suffer from losses. Therefore, it is of utmost importance to find out how the personality of a negotiator would affect the negotiation process and outcome. This will help them choose the right candidates. It will also help them choose the right training for them and will minimize waste of investment. Many studies have been conducted in in this field. What other authors have written has The Impact of the Negotiator’s Personality on the Negotiation process . Salah Ahmed Mohamed Amer ششع عثاشنا ذهجًنا يَبضنا دذعنا ميشثإ 0202 401 formed the basis and guidelines for the discussion of the empirical work. The research purpose is to explore further, which personality traits would be most adequate for a negotiator and whether a good negotiator can be 100% made; or whether he has to possess a talent on which a firm can build further by training to make him acquire the necessary skills. For the empirical work of this study, I have sent out 320 questionnaires, all of which I received answers for, adopting a quantitative approach. All candidates chosen had differed related professions (buyers, salesmen, HR people and senior management). The answers of these questionnaires answered all five hypothesis and questions of this research. The conclusion of this research was that the negotiator’s personality had a great effect on the negotiation process and outcome and that a negotiator had to possess some talent on which an organization can build to reach the required skills. Also, that the best development method for a negotiator was practice and coaching as well as training courses and preferably if all methods were combined together. Additionally, the study pointed out which were the most important personality traits essential for a good negotiator. From the point of view of the various negotiators, these turned out to be openness, conscientiousness and emotional stability. Another The Impact of the Negotiator’s Personality on the Negotiation process . Salah Ahmed Mohamed Amer ششع عثاشنا ذهجًنا يَبضنا دذعنا ميشثإ 0202 401 finding was that the most appealing negotiation approach was the collaborative approach. However, both literature and real-life stakeholders agreed on the necessity of the negotiator’s ability to adapt his/her style according to the situation at hand. The findings offer invaluable information on many aspects of the negotiation process and the negotiator himself, and could form the basis for future studies.
The Inﬂuence of Digital Based Political Marketing on Governor Election Decisions in the 2020 Simultaneous Regional Elections with Political Trust as a Moderating Variable

This study aims to determine the effect of digital-based political marketing on the decisions of Mahyeldi Ansharullah and Audy Joinaldy voters in the 2020 simultaneous regional elections with political trust as a moderating variable. The population of all people in West Sumatra who are over 17 years old and have the right to vote as many as 726,853 voters. The sampling technique used cluster sampling. The number of samples using the Slovin formula is 400 respondents. The analysis method uses SEM PLS with the SmartPLS program 3. The results show that the variables political product, political promotion, political process, political physical evidence, political power, and political public opinion have a positive and insigniﬁcant effect on election decision. The political trust variable has a positive and signiﬁcant effect on election decision. Political price, political place and political people variables have a negative and insigniﬁcant effect on election decision. The variables of political product, political promotion, political price, political people, and political physical evidence have a positive and insignif-icant effect on election decision with political trust as a moderating variable. The variables political place, political process, political power, and political public opinion have a negative and insigniﬁcant effect on election decision with political trust as a moderating variable.
A comparative study of two different doses of dexmedetomidine for attenuating the haemodynamic response to tracheal intubation

Back ground: Reflex sympathetic discharge caused by laryngo-pharyngeal stimulus with laryngoscopy may lead to hypertension and tachycardia. It is one of the cause for morbidity during general anesthesia. We in our study compared the two doses of Dexmedetomidine1 µg/kg and 0.5 µg/kg for attenuating this response. Material and Methods: In this study ninety patients were randomly divided into two groups. Group A Received: 0.5µg/kg Injection Dexmedetomidine as bolus dose over 10 minutes & Group B - Received: 1µg/kg Injection Dexmedetomidine as a bolus dose over 10 minutes. The heart rate and blood pressure (Systolic, diastolic and mean) of the patient were noted at following intervals preoperative i.e. Baseline, during administration of the study drug at 2 minutes, 4 minutes, 6 minutes, 8 minutes, and 10 minutes, immediately at induction, At intubation and Post intubation at 1min, 5 min and 10 min. Statistical significance in mean difference was calculated using student’s t test. P value of < 0.05 was regarded as statistically significant and p < 0.001 was taken as highly significant. Results: Compared to the baseline all the hemodynamic parameters (HR, SBP, DBP and MAP) showed decrease during administration of the study drug which continued throughout the study period except at intubation and 1 min post intubation in both the groups. These values still remained below the baseline value. Highly significant difference in heart rate in both the groups was noted at 5 and 10min post intubation Group B showing more decrease than A(p=0.000, 0.001). Same statistical significance is noted in systolic blood pressure at induction and at 10 min. post intubation (p=0.000, 0.000). Mean blood pressure (p=0.03, 0.03) and diastolic blood pressure (p=0.000, 0.001) also showed more decrease in Group B than A at 5 and 10 min post intubation with high statistical significance. Conclusion: Dexmedetomidine in the dose of 0.5 µg/kg and 1µg/kg is effective in attenuating the hemodynamic response to laryngoscopy and tracheal intubation
Effect of educational program regarding eye infection care on mothers' performance and their children outcomes

Background: Eye infections are one of the most common eye diseases in children and the most common ophthalmic complaint seen in emergency departments around the world. Aim of the study was to determine the effect of educational program regarding eye infection care on mothers' performance and their children’s outcomes. Subjects and Method: A quasi-experimental research design was used in the study. Subjects: A convenience sampling of 80 mothers and their children with eye infection; forty mothers and their children from Out-patient clinic at ophthalmology of Tanta city which affiliated to Ministry of health and population and 40 mothers and their children from Outpatient pediatric clinic at ophthalmic units of Zifta Ophthalmic Hospital which affiliated to Ministry of Health and population. Three Tools were used for data collection: Tool (I): Mothers’ knowledge and socio -demographic data. Tool (II): Self-report mothers’ practices, Tool (III): observational check list for children’s outcomes. Results: the main results revealed that there were highly statistically significant differences between the pretest and post-test of educational program implementation. Conclusion: the present study findings revealed that mothers had poor knowledge and inadequate practices related to eye infection and its management. Recommendations: Classes and educational programs for mothers about the management and prevention of eye infection should be held at all Ophthalmic Hospitals in El-gharbia governorate .
Saudi EFL Teachers’ and Students’ Perceptions Towards Using English-Arabic Code Switching as a Teaching and Learning Strategy

This study aimed to investigate EFL (English as a foreign language) teachers’ and students' perceptions towards using CS (code-switching) in teaching and learning English at Saudi secondary schools. It also attempted to identify EFL teachers and students' reasons for using CS in teaching and learning English in Saudi high schools. The sample of the study consisted of 100 teachers and 122 students who were randomly selected from secondary schools in the city of Riyadh. The data of the study were collected via a five-point Likert scale questionnaire. Moreover, this instrument was validated by ten university EFL professors, and its reliability was achieved by calculating Cronbach Alpha formula. The findings of the study revealed that teachers and students believed that CS was an effective strategy in helping students to understand unfamiliar topics, facilitating students’ learning of new grammatical structures, increasing student-teacher interaction, and enlivening the atmosphere of the class. Finally, teachers and students agreed that the most important reasons behind using CS were increasing comprehension, avoiding misunderstanding, eliciting better responses from students, and filling gaps in a classroom conversation.
Continuance Intention to Use Online Learning Platform during COVID-19 Pandemic: Perspective from Young Customers of Higher Learning Institutions 
In Northwest Borneo Island (Sarawak)

The COVID-19 pandemic in 2020 necessitated a transition to remote and online learning in the education sector to mitigate the virus's spread. However, the adoption of online learning faced challenges related to hardware and software, resulting in low usage rates. Despite the increased interest in online learning during the pandemic and the variations in study locations, certain findings in this research were incongruent, offering a distinct viewpoint on the acceptance or utilisation of online learning platforms. Hence, this study aimed to examine the influence of perceived usefulness, interactive learning, and self-efficacy on satisfaction and the intention to continue using online learning platforms among young customers in higher learning institutions on Northwest Borneo Island (Sarawak). Data from 219 participants with prior experience using online learning platforms were collected through an online questionnaire. The study employed SmartPLS 4 and utilised Partial Least Squares – Structural Equation Modeling (PLS-SEM) method to test the proposed hypotheses. The findings underscore the significant influence of perceived usefulness, interactive learning, and self-efficacy on students' satisfaction and intention to continue using online learning platforms. Theoretically and practically, this study adds to the existing literature on online learning platforms, offering valuable insights for educational institutions and policymakers seeking to enhance student satisfaction and promote the continued use of such platforms
Impact of oxygen plasma postoxidation process on Al2O3/n-In0.53Ga0.47As metal-oxide-semiconductor capacitors

Capacitance-voltage (C-V) measurements and x-ray photoelectron spectroscopy (XPS) analysis were performed in order to investigate the effect of a oxygen (O2) plasma after oxide deposition on the Al2O3/n-In0.53Ga0. 47As metal-oxide-semiconductor structure passivated with ammonia NH4OH solution. From C-V measurements, an improvement of charge control is observed using the O2 plasma postoxidation process on In0.53Ga0. 47As, while the minimum of interface trap density remains at a good value lower than 1 × 1012 cm−2 eV−1. From XPS measurements, we found that NH4OH passivation removes drastically the Ga and As native oxides on the In0.53Ga0. 47As surface and the O2 plasma postoxidation process enables the reduction of interface re-oxidation after post deposition annealing (PDA) of the oxide. The advanced hypothesis is the formation of interfacial barrier between Al2O3 and In0.53Ga0. 47As which prevents the diffusion of oxygen species into the semiconductor surface during PDA.
Electromagnetic plane wave scattering from a cylindrical object with an arbitrary cross section using a hybrid technique

ABSTRACT A hybrid technique combining finite-element and mode-matching methods for the analysis of scattering problems in open and closed areas is presented. The main idea of the analysis is based on the utilization of the finite-element method to calculate the post impedance matrix and combine it with external excitation. The discrete analysis, which is the most time- and memory-consuming, is limited here only to the close proximity of the scatterer. Moreover, once the impedance matrix is calculated, any rotation or shifting of the post can be performed without the need for structure recalculation. All the obtained results have been verified by comparison with simulations performed using the hybrid finite-difference-mode-matching method and commercial software.
Fractional Integration and Fractional Differentiation of the M-Series

In this paper a new special function called as M-series is introduced. This series is a particular case of the H-function of Inayat-Hussain. The M-series is interesting because the pFq-hypergeometric function and the Mittag-Leffler function follow as its particular cases, and these functions have recently found essential applications in solving problems in physics, biology, engineering and applied sciences. Let us note that the MittagLeffler function occurs as solution of fractional integral equations in those area. In this short note we have obtained formulas for the fractional integral and fractional derivative of the M-series. Mathematics Subject Classification: 26A33, 33C60, 44A15
Sharing Economic Partnership on Online Transportation

The model sharing economy concept in online using transactions through the coordination of applications that are connected to the internet. The aims of this study were to explain the influence factors asymmetric information and transaction costs on the partnership relation in the online mode of transportation in Indonesia. This study applies PLS-SEM analysis to explore the phenomena that occur in online drivers. The results showed is a significant positive effect of the asymmetric information factor on the transaction cost factor. Then the transaction cost variable does not have a significant effect on the partnership relationship factor. While the information asymmetry factor has a significant effect on the partnership relationship. Asymmetric information that occurs related to transaction information, incentive information and sanction information. The implication of the asymmetry that occurs to the driver causes the driver to lose bargaining power as a partner. Although drivers have experienced an increase in income, their job security is very unstable. The role of the government is needed to oversee and provide regulations to reduce asymmetric information, balance the bargaining power of drivers and the sustainability of their jobs.
Painful Diabetic Peripheral Neuropathy – A Survey of Patient Experiences

Purpose An online survey was conducted in the USA to obtain information about the knowledge and experiences of patients with painful diabetic peripheral neuropathy (pDPN). Patients and Methods 506 adults with diabetes and pDPN affecting the feet for ≥6 months, for which pain medication had been prescribed for ≥6 months, completed an online survey questionnaire in March 2021. Results 79% of respondents had type 2 diabetes, 60% were male, 82% were Caucasian and 87% had comorbidities. Pain was significant to severe in 49% of respondents, and 66% had disability due to nerve pain. Anticonvulsants, over-the-counter pills and supplements were the most commonly used medications. Topical creams/patches were prescribed in 23% of respondents. 70% had tried multiple medications for their pain. 61% of respondents had to see ≥2 doctors before receiving a correct diagnosis of pDPN. 85% of respondents felt that the doctor understood their pain and its impact on their life. 70% had no difficulty finding the information they wanted. 34% felt insufficiently informed about their condition. A medical professional was the primary, and most trusted, source of information. Frustration, worry, anxiety and uncertainty were the most commonly reported emotions. Respondents were generally eager to find new medications for pain relief and desperate for a cure. Lifestyle changes because of nerve pain were most commonly associated with physical disabilities and sleep disturbance. Better treatments and freedom from pain were the overriding perspectives when considering the future. Conclusion Patients with pDPN are generally well informed about their pain and trust their doctor but remain unsatisfied with their current treatment and struggle to find a lasting solution for their pain. Early identification and diagnosis of pain in diabetics, and education about treatments, is important to minimize the impact of pain on quality of life and emotional well-being.
Nutritional status of reproductive age group women: A community-based study

Introduction: Anemia continues to be a major public health problem worldwide, particularly among females of reproductive age in developing country settings. The prevalence of anemia in South Asia is among the highest in the world, mirroring overall high rates of malnutrition. Objective: 1) To estimate the prevalence of anemia and undernutrition among reproductive age group females. 2) To study factors associated with anemia and undernutrition among reproductive age group females. Material and Method: This was cross-sectional study, which was carried out from June 2011 to December 2012 at Nanded City in Maharashtra state among nonpregnant ever-married women of 15–49 years age with a sample size of 750 selected using probability proportional to size sampling technique. Percentage, Chi-square test, analysis of variance (ANOVA) test, and Student's t test were used for analyzing the data. Results: The prevalence of anemia among reproductive age group women was 554 (73.9%). 20.8% of women were undernourished and 4.1% were obese. There was a significant difference in the hemoglobin percentage of study subjects in relation to their age at marriage, weight, and body mass index (BMI). Mean BMI increases significantly as the age of women and duration of marriage increases. Conclusion: Nutritional status has a significant effect on the grade of anemia. Women of reproductive age groups are affected by anemia irrespective of age and parity.
Wounded warriors: Multiple identities, physical activity and life satisfaction

Purpose: The purpose of the current study was to examine a model specifying that military, athlete, exercise, and disability identities would predict life satisfaction as mediated by physical activity (PA). Methods: Seventy-one military veterans (N = 71) with impairments participated and completed Exercise, Athlete, Disability, Military, identity scales and Life Satisfaction and PA questionnaires. Results: A mediation model indicated the indirect effect of the four identities on life satisfaction through PA was not significant However, PA was predicted by the 4 identities, [F (4, 66) = 2.49, p = 0.05] and accounted for 13% of the variance, with disability identity having the only significant beta weight. Life satisfaction was also predicted by the 4 identities and PA ([F (5, 65) = 4.88, p = 0.001] and accounted for 27% of the variance. However, only the military and athletic identities had significant beta weights. Conclusions: Our findings provide preliminary support for the value of military veterans maintaining a military identity and holding an athletic identity. The current findings suggest that sport psychologists and rehabilitation professionals take a more nuanced and open-minded perspective about veterans who desire to maintain a military identity when becoming civilians.