Miracle-dz/UniFAR-FTUs huggingface dataset:
Les voies du transport intraflagellaire

Les cils sont des organites essentiels chez la plupart des eucaryotes. Ils sont construits par un mecanisme appele transport intraflagellaire (IFT). Dans cette these, nous avons etudie le role de l'IFT chez le protiste Trypanosoma brucei. Par une combinaison d'approches en video-microscopie et en microscopie electronique, nous avons revele que l'IFT est absent ou s'arrete apres ciblage par ARNi de genes requis pour le transport aller et retour. Dans ces conditions, nous avons demontre que l'IFT n'est pas necessaire au maintien de la longueur du flagelle mature mais controle la distribution de plusieurs proteines non structurales. Les trains IFT transportent la tubuline, le constituant majeur de l'axoneme. En collaboration avec l'equipe d'Esben Lorentzen, nous avons mis en evidence l'existence d'un module de liaison a la tubuline sur les proteines IFT74/IFT81. Par FIB-SEM, nous avons demontre que les trains IFT sont presents presque exclusivement sur seulement deux (4 et 7) des 9 doublets de microtubules du flagelle. L'utilisation de methodes d'imagerie super resolutives par SIM, a permis de montrer sur cellules vivantes, l'existence de deux voies specifiques pour le trafic IFT aller et retour. Cette restriction s'explique par la presence d'une polyglutamylation plus marquee de la tubuline au niveau de ces doublets. L'inhibition des enzymes responsables de la polyglutamylation freine l'acces des proteines IFT aux flagelles et interfere severement avec la construction de l'organite. Ces travaux demontrent donc un role essentiel de la polyglutamylation, qui serait lu par les moteurs du transport intraflagellaire.
Revaluation of Australian palm residues in polypropylene composites: Statistical influence of fiber treatment

Australian palm residues are generated by palm heart industry in large quantities and are considered an underused material with a composition rich in lignocellulosic structures. This residue is generally utilized as briquettes for energy or sheep feed; however, few works investigate this residue as composite fillers. This work aimed to revalue Australian palm residues (PR) by preparing polypropylene composites through melt mixing, using different fiber contents (0, 5, 10, 20, and 30 wt%), and evaluate the statistical influence of fibers (residues) alkali treatment (MPR) in composites mechanical properties. PR and MPR were evaluated by FTIR, XRD, SEM, TGA, and composites were assessed using thermal and mechanical analysis, in which ANOVA statistical analysis was applied. The residues addition increased the mechanical properties and their treatment enhanced the stiffness of the composites compared to pristine PP. However, ANOVA demonstrated that at low residues contents, surface treatment does not increase fiber-matrix interactions effectively, then tensile properties were statistically similar to PP. Considering tensile properties, 20% MPR showed statistically distinct properties, with significative enhancements; no filler contents dependence was verified. Flexural properties were more sensitive to residue loading, and composites with 30% PR and MPR presented superior mechanical performance. This difference is associated with a higher sensitivity of tensile stress towards fiber-matrix interactions, which was improved with fiber treatment. Also, the residues content and treatment influenced the composites' thermal stability, with better results for PP-MPR. Results indicate that palm residue is an excellent filler for improving composites' thermal and mechanical properties, with a greener character.
Marble Sculptures from the Great Eastern Baths of Gerasa (Jordan): The Sources of the Marbles

This paper aims to examine the provenance of Roman marble statues uncovered from the Eastern Roman Baths (Gerasa of the Decapolis, Jordan) during the 2016 and 2017 excavation campaigns. The samples were characterized using magnifying lenses, an x-ray diffractometer, a stable isotope mass spectrometer, and a polarized light microscope. The results show that the Aphrodite and drapery marbles are dolomitic and most probably from the Cape Vathy of Thassos Island (Greece); the Asklepios and Zeus marbles are fine-grained and most probably from Docimium (Turkey); the Melopmene, Demetrius Aphrodite, and eagle marbles are fine-grained and most probably from Penteli (Greece); the dancing satyr and Apollo marbles are coarse-grained and most probably from Lakkos (Paros Island, Greece); and the marble fragments of unknown statues are coarse-grained and most probably from Marmara (Proconnesus-1) Island, Turkey. The results indicate that sculptors preferred fine white marbles for carving sculptures in spite of their source, price, and sculpture workshop. The results agree with previous studies that showed a wide variety of marble sources, indicating that Gerasa prospered in its location on the King’s Highway and participated in a well-established trade network with the major cities and marble sources in the Roman Empire.
Distinguishing relational turbulence, marital satisfaction, and parenting stress as predictors of ineffective Arguing among parents of children with autism

Relational turbulence theory suggests that relational turbulence causes pervasive patterns of dysfunctional communication in romantic relationships, such as an inability to resolve conflicts. Other research traditions link marital conflict to marital satisfaction and also exposure to stress. This study assesses the discriminant validity of relational turbulence by examining its association with reports of ineffective arguing, above and beyond the associations with marital satisfaction and parenting stress. The study tests the theoretical claims within the high stress context of parents raising children with autism spectrum disorder (ASD). Married, parents of children with ASD (N = 298) completed measures of parenting stress specific to raising a child with ASD, marital satisfaction, relational turbulence, and ineffective arguing. Results provide evidence that relational turbulence is associated with perceptions of less effective arguing among these parents above and beyond the influence of parenting stress and marital satisfaction. Finally, implications for marriages, for parents of children with ASD, and for relational turbulence theory are discussed.
Crude glycerine as an alternative energy feedstuff for beef cattle grazing tropical pasture

SUMMARY The purpose of the current study was to evaluate the effect of different levels of crude glycerine (CG, 810·9 g glycerol/kg) replacing dry ground maize on intake, digestibility, microbial nitrogen (N) synthesis and N utilization in grazing beef cattle. Five Nellore bulls (332 ± 29·6 kg initial body weight (BW)) were used in a 5 × 5 Latin square design. The animals grazed five Marandu grass (Urochloa brizantha cv. Marandu) paddocks of approximately 0·32 ha. Five supplements were evaluated: mineral supplementation (control, only ad libitum access to a mineral mixture) and 4 g of protein-energy supplementation/kg of BW with four levels of CG (0, 330, 660 and 1000 g/kg) replacing dry ground maize. Bulls that received protein-energy supplementation had greater organic matter (OM) pasture and digested OM (DOM) intakes than the control. No differences were observed among CG levels with regard to OM pasture, neutral detergent fibre and DOM intakes. However, ether extract intake increased linearly as CG levels increased. Protein-energy supplementation enhanced efficiency of microbial N synthesis, N balance and ammonia concentration, but they were not influenced by the CG levels. In conclusion, partial or total replacement of dry ground maize by CG in protein-energy supplements for grazing beef cattle exerted no changes on pasture intake, digestibility and N utilization. Therefore, the use of CG as an energy source in supplements for grazing cattle can be recommended.
Trade‐offs between biodiversity and agriculture are moving targets in dynamic landscapes

1Instituto de Ecología Regional (IER), CONICET Universidad Nacional de Tucumán, Tucumán, Argentina; 2Instituto de Recursos Biológicos (IRB-CIRN), Instituto Nacional de Tecnología Agropecuaria (INTA), Buenos Aires, Argentina; 3Grupo de Estudios de Agroecosistemas y Paisajes Rurales (GEAP), CONICET Universidad Nacional de Mar del Plata, Buenos Aires, Argentina; 4Agencia de Extensión Rural San Luis, Instituto Nacional de Tecnología Agropecuaria (INTA), San Luis, Argentina; 5Geography Department, Humboldt-Universität zu Berlin, Berlin, Germany and 6Integrative Research Institute on Transformations of Human-Environment Systems (IRI-THESys), Humboldt-Universität zu Berlin, Berlin, Germany
CYTOTOXIC ACTIVITY OF ALKALOIDS EXTRACTED FROM THREE IRAQI PLANTS AGAINST BREAST CANCER CELL LINE

Objectives: Screening for cytotoxic activity of total alkaloid extracts of Eucalyptus camaldulensis , Aloe vera, and Capparis spinosa against breast cancer cell line Michigan Cancer Foundation-7 (MCF-7) and nontumorigenic fetal hepatic cell line (WRL-68). Methods: The plant powders were extracted separately with 80% methanol and chloroform at pH 2 and 10. Total alkaloids were detected qualitatively by Mayer’s, Dragendorff’s, and Hager‘s reagents and estimated quantitatively by bromocresol green spectrophotometry depending on the atropine calibration curve. The cytotoxic activity was evaluated by 3-[4, 5-dimethylthiazoyl]-2, 5-diphenyltetrazolium bromide assay. Results: The extract of E. camaldulensis had highest total alkaloid content (24.50±1.70 mg/100 g plant dry weight) than the others. The total alkaloids (400 μg/ml) of E. camaldulensis reduced the cell viability of both cell lines MCF-7 and WRL-68 to 45.25±2.20% and 92.00±1.55%, respectively, and the inhibitory concentration 50% of cells were 375.50 μg/ml for MCF-7. The alkaloids of C. spinosa had effect 79.80±7.08% and 89.50±0.09% against MCF-7and WRL-68, respectively. While the total alkaloids of A. vera had slightly effect on both cell lines. Conclusion: Plant alkaloids appeared variable cytotoxic activity against cancer and normal cell lines depending on the alkaloid contents, concentrations, purity, and cell line types.
Transcultural literacies in online collaboration: a case study of fanfiction translation from Russian into English

ABSTRACT This study analyses the transcultural meaning-making and literacies that arise during the amateur translation of a fanfiction novel from Russian to English. We applied digital ethnography to make observations of the translation process and interviews with the participants. Transcultural meaning-making was identified during their discussions on how to adapt a Russian fanfiction novel for a global English-speaking readership. During the discussions the participants creatively mixed different linguistic and cultural resources. They also positioned themselves as mediators between two readerships, which pushed them to reflect on literary and philosophical traditions of the Russian and English-speaking cultures and engage in transcultural literacies.
Work–Family Conflict on Sustainable Creative Performance: Job Crafting as a Mediator

The psychology of sustainability in terms of sustainable development for work–family conflict (WFC) in organizations has become increasingly relevant in sustainable human resource management research, and the pursuit of sustainable creative performance is an important aspect of corporate sustainable development. Taking a regulatory focus perspective, this study integrates a moderated-mediation model to examine the relationship between work–family conflict and sustainable creative performance. Data were collected from 203 supervisor–subordinate dyads from two branches of a high-end manufacturing enterprise in Shanghai, China. The results reveal that work–family conflict has a positive effect on sustainable creative performance through job crafting, and the effect is stronger when individuals show higher promotion regulatory focus. We discuss the theoretical and practical implications of the study, along with potential future research directions.
Building a Thriving Organization: The Antecedents of Job Engagement and Their Impact on Voice Behavior

For an organization to become sustainable, it is essential to keep employees engaged in their jobs with enthusiasm. Thus, this study presents and tests an integrative model of job engagement. Based on Kahn’s model, we adopted person–job fit (P–J fit), psychological contract fulfillment, and self-efficacy as the antecedents of job engagement, verified how these antecedents affect job engagement, and examined how they influence voice behavior. Data were collected from 189 subordinate–supervisor dyads from public corporations and private enterprises in South Korea. The results of the analysis suggested that all antecedents have positive relationships with job engagement. We also found that job engagement is positively related to employees’ voice behavior, and fully mediates the relationships between the antecedents and voice behavior. Moreover, our findings suggested that perceived coworker support moderates the relationship between job engagement and voice behavior.
Clinical and pathological findings in a Dwarf Red Brocket Mazama rufina (Mammalia: Cetartiodactyla: Cervidae) attacked by dogs

Capture myopathy is a common fatal syndrome in wild ungulates resulting from anthropogenic stressful events such as the capture or transport of specimens. There are, however, few published data on this issue due to predator attacks. The present report describes for the first time the capture myopathy syndrome in a Dwarf Red Brocket Mazama rufina following dog Canis familiaris attack. Clinical signs included pale mucous with increase capillary refill time, tachycardia, tachypnea, hypertension, hypothermia, hypoglycemia, and red brown urine. Muscle tremors, ataxia, prostration, paralysis, and opisthotonus were progressively observed. Laboratory tests showed increased levels of cortisol, creatinine, creatine kinase, lactate dehydrogenase, and potassium; decreased blood urea nitrogen-creatinine ratio; and myoglobinuria. The animal died 72 hours after hospital admission. At necropsy, findings included injuries on both hindlimbs with edema, emphysema, and soft-friable texture in affected muscles, dark kidneys and brown urine in bladder. Histopathological exams were indicative of skeletal-cardiac muscle degenerative lesions and myoglobinuric nephrosis. Immuno-histochemistry revealed myoglobin depletion in degenerate muscles and myoglobin accumulation in renal tissues. We strongly recommend that treatment for capture myopathy be initiated when a wild ungulate is admitted with history of predator attack, since the syndrome may have already established. This report adds to the instances of negative impacts caused by domestic dogs on threatened wildlife species.
Hands in Motion

Irish Sign Language uses a one-handed alphabet in which each fingerspelled letter has a unique combination of handshape, orientation, and, in a few cases, path movement. Each letter is used to represent a letter from the Latin alphabet (Battison, 1978; Wilcox, 1992). For ISL learners, fingerspelling is a strategy that is used to bridge lexical gaps, and so functions as an interlanguage mechanism, which we hypothesise is more prevalent for new learners (A-level learners in the Common European Framework of Reference for Languages (CEFR) (Council of Europe, 2001). Across 2018–19 we marked up a subset of data from the Second Language Acquisition Corpus (ISL-SLAC) for use of fingerspelling. Here, we document how these learners use fingerspelling, and explore the phonology of the fingerspelled items presented by M2L2 learners (handshape, location, movement and orientation), comparing to the production of native signers’, drawn from the Signs of Ireland corpus. Results indicate that ISL learners make greater use of fingerspelling in the initial phases of acquiring the language, and that, over time, as they develop a robust lexical repertoire, they reduce the frequency of fingerspelling. Fingerspelling also provides a strategic interlanguage that can be reverted to when vocabulary is unknown.
Treatment of cloacal papilloma with 50% silver nitrate solution in chestnut-fronted macaws (Ara severus)

Cloacal papilloma is commonly found in Amazon parrots and macaws. There are many treatment options for cloacal papilloma. Chemical cautery is one of the recommended methods. In this study, 6 mature chestnut-fronted macaws (Ara severus) with cloacal papilloma were treated weekly with 50% silver nitrate solution. All tumors completely regressed after 2 to 5 weeks of treatment. One bird died after the second treatment from another cause. Three months after the last treatment, one bird died from internal papilloma in the esophagus and the crop. Recurrence was found in one bird at 6 months after the last treatment. The result suggested that cauterization with 50% silver nitrate solution was effective in the treatment of cloacal papilloma in macaws. However, recurrence of the tumor or papilloma in the gastrointestinal tract could be observed.
Approximate Cache in GPGPUs

There is a growing number of application domains ranging from multimedia to machine learning where a certain level of inexactness can be tolerated. For these applications, approximate computing is an effective technique that trades off some loss in output data integrity for energy and/or performance gains. In this article, we present the approximate cache, which approximates similar values and saves energy in the L2 cache of general-purpose graphics processing units (GPGPUs). The L2 cache is a critical component in memory hierarchy of GPGPUs, as it accommodates data of thousands of simultaneously executing threads. Simply increasing the size of the L2 cache is not a viable solution to keep up with the growing size of data in many-core applications. This work is motivated by the observation that threads within a warp write values into memory that are arithmetically similar. We exploit this property and propose a low-cost and implementation-efficient hardware to trade off accuracy for energy. The approximate cache identifies similar values during the runtime and allows only one thread writes into the cache in the event of similarity. Since the approximate cache is able to pack more data in a smaller space, it enables downsizing of the data array with negligible impact on cache misses and lower-level memory. The approximate cache reduces both dynamic and static energy. By storing data of a thread into a cache block, each memory instruction requires accessing fewer cache cells, thus reducing dynamic energy. In addition, the approximate cache increases frequency of bank idleness. By power gating idle banks, static energy is reduced. Our evaluations reveal that the approximate cache reduces energy by 52% with minimal quality degradation while maintaining performance of a diverse set of GPGPU applications.
Peer groups, street gangs and organised crime in the narratives of adolescent male offenders

Purpose The purpose of this paper is to explore how young people who offend with others define delinquent and criminal groups and consider the social risk factors associated with gang membership and criminal exploitation. Design/methodology/approach The sample consisted of 15 young people who were purposively sampled from a group of 14- to 17-year-old males who had been identified as at risk of gang involvement and referred to a community-based programme. Using a social identity framework, a thematic analysis was undertaken to investigate how the participants viewed their role in offending as part of a group. Findings The participants identified peer groups, street gangs and the involvement of adult criminals as distinct categories of offending groups. Unlike prior models for gang involvement, some members of the sample were involved in multiple groups to perform different categories of crime. Importantly, participants displayed an awareness of exploitation and described successful exit strategies from criminal groups. Research limitations/implications Understanding how young people who are involved in delinquent behaviour and offending define gang and group offending. Practical implications The implications for gang and group offending prevention and intervention programmes are discussed. Originality/value The literature on child criminal exploitation and UK drug markets is in its infancy. This paper offers further evidence for the processes of joining and leaving delinquent and criminal groups.
USEFULNESS OF MOBILE TEACHING AND LEARNING AS PERCEIVED BY ROMANIAN AND LITHUANIAN SCIENCE TEACHERS

With the explosion of mobile technologies, mobile teaching and learning became an important educational challenge. Since both teachers and students are increasingly using mobile devices in their everyday life, the question is why so little progress has been made in this direction. Clearly, the initiative of introducing mobile technology in class should come from teachers. Existing research shows a large diversity of factors that are influencing their perception as regards the usefulness and opportunity of mobile teaching and learning. This research aims to understand the extent to which the expectancy of increased students’ motivation and better understanding are influencing the perception of mobile teaching usefulness. A structural model has been developed and tested on two samples of science education teachers, one from Romania and the other from Lithuania. The results show that the expectancy of a better understanding of lessons by students has an important effect on the teachers’ perception of mobile teaching and learning.
RESISTÊNCIA ANTIMICROBIANA EM SALMONELLA ENTERICA SUBSP. ENTERICA SOROVAR HADAR ISOLADAS DE CARCAÇAS DE FRANGO

RESUMO A resistência antimicrobiana é um assunto amplamente estudado em todos os gêneros bacterianos, sobretudo em relação aos responsáveis por zoonoses, como o caso da Salmonella, a qual merece especial atenção, já que pode ser transmitida para os seres humanos. O presente estudo foi conduzido para verificar a ocorrência de resistência a agentes antimicrobianos em 22 cepas de Salmonella Hadar isoladas de carcaças congeladas de frango no Estado do Rio Grande do Sul, no período de maio de 1995 a abril de 1996. No presente estudo, os resultados indicaram que 100% das cepas de Salmonella Hadar apresentaram resistência a tetraciclina, estreptomicina e sulfazotrim, tendo também apresentado resistência em diferentes níveis ao ácido nalidíxico (86,36%), nitrofurantoína (18,18%) e cloranfenicol (4,54%). Todas as cepas de Salmonella Hadar apresentaram resistência a três ou mais agentes antimicrobianos, com cinco diferentes padrões de resistência. Os níveis de resistência observados enfatizam a necessidade do uso responsável dos agentes antimicrobianos na produção animal.
Multilevel Methods and Statistics: The Next Frontier

The purpose of this article is to take stock of extant multilevel methodological and statistical work and highlight needed areas for future research. A basic overview of the history and progression of multilevel methods and statistics in the organizational sciences is provided, as well as a discussion of recent developments to summarize the current state of the science. The eight articles in the current feature topic are also summarized and integrated to depict several themes and directions for the next wave of multilevel methods and statistics. Last, to highlight what still needs to be accomplished in the field, several unresolved issues and future research topics are noted and an agenda related to future multilevel work is discussed.