Miracle-dz/UniFAR-FTUs huggingface dataset:
Impact of Novel Technologies on Virgin Olive Oil Processing, Consumer Acceptance, and the Valorization of Olive Mill Wastes

: There is a growing consumer preference for high quality extra virgin olive oil (EVOO) with health ‐ promoting and sensory properties that are associated with a higher content of phenolic and volatile compounds. To meet this demand, several novel and emerging technologies are being under study to be applied in EVOO production. This review provides an update of the effect of emerging technologies (pulsed electric fields, high pressure, ultrasound, and microwave treatment), compared to traditional EVOO extraction, on yield, quality, and/or content of some minor compounds and bioactive components, including phenolic compounds, tocopherols, chlorophyll, and carotenoids. In addition, the consumer acceptability of EVOO is discussed. Finally, the application of these emerging technologies in the valorization of olive mill wastes, whose generation is of concern due to its environmental impact, is also addressed.
PGPM_A_319524 927..945

1Department of Hepatic Surgery and Liver Transplant Program, The Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou, People’s Republic of China; 2Department of Infectious Diseases and Hepatology Unit, Nanfang Hospital, Southern Medical University, Guangzhou, People’s Republic of China; 3Guangdong Key Laboratory of Liver Disease Research, The Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou, People’s Republic of China; 4Department of Hepatobiliary Surgery, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, People’s Republic of China
BTT_A_290323 451..462

1Department of Oncology, San Bortolo General Hospital, AULSS8 Berica, Vicenza, Italy; 2Department of Oncology, University Hospital, Udine, Italy; 3Department of Health Sciences, Section of Clinical Pharmacology and Oncology, University of Firenze, Firenze, Italy Abstract: Gastric cancer (GC) is a complex and heterogeneous disease with poor prognosis and limited available treatment options. During recent years, several molecular stratifications have been proposed to optimize the overall treatment strategy for GC patients. Breakthroughs in cancer biology and in molecular profiling through DNA and RNA sequencing are now opening novel landscapes, leading to the personalization of molecular matched therapy. In particular, therapies against HER2, Claudine 18.2, Fibroblast Growth Factor Receptors (FGFR), and other molecular alterations could significantly improve survival outcomes in the advance phase of the disease. Furthermore, immunotherapy with checkpoint inhibitors also represents a promising option in a selected population. Hoping that precision oncology will enter soon in clinical practice, our review describes the state of the art of many novel pathways and the current evidence supporting the use of monoclonal antibodies implicated in GC treatment.
Weathering under coastal hyperaridity e Late Quaternary development of spectral, textural, and gravelometric alluvial fan surface characteristics

and sea in However, neither the geomorphic effects of the weathering processes nor the timescales on which they alter depositional surfaces are suf ﬁ ciently understood. In study we integrate spectral, textural, and gravelometric analyses based on high to very high resolution satellite and aerial remote sensing to assess the degree of post-depositional alteration of a multi-stage alluvial fan at the coast of the Atacama Desert. To further deduce the present-day as well as past intensities of responsible weathering processes we establish a morphochronology of the fan's evolution using cosmogenic 10 Be exposure dating. Spectral, textural, and gravelometric parameters relatively date a succession of fan generations, assuming the weathering of fan surface sediments prior to deposition can be largely excluded. Under coastal hyperaridity, effects on the spectral surface signatures are primarily explained by the development of weathering rinds and related formation of secondary iron oxides. Spectral iron oxide ratios show little to no change during the Holocene but strongly increase during the Late Glacial, while over longer timescales an asymptotic increase is suggested. Clast breakdown can largely be attributed to salt weathering causing sublinear to roughly linear decreases in mean size, coarseness, and size variation of coarse clasts. Governed by clast breakdown as well as lateral remobilization of clasts, nano-scale surface roughness exhibits a non-monotonic, peak-shaped relationship with age, whereas the micro-relief ex-periences continuous smoothing due to denudation. Findings are summarized in a conceptual model showing that in hyperarid coastal environments fan surface weathering results over timescales of 10 4 to 10 5 a in a fully developed desert pavement. Two hypothetical scenarios are introduced which differ based on whether desert pavements remain stable over timescales exceeding the Late Pleistocene or not. Late Quaternary weathering intensity along the coast of the Atacama Desert is found to be related to sea surface temperature variability and sea level jointly driving the oceanic moisture supply.
Comparison of the effects of and usability of active and active-assistive rehabilitation robots for the upper extremity function among patients with stroke: a single- blinded randomized controlled pilot study

Jin Ho Park National Rehabilitation Center https://orcid.org/0000-0001-6536-0275 Gyulee Park National Rehabilitation Center Ha Yeon Kim National Rehabilitation Center Ji-Yeong Lee National Rehabilitation Center Yeajin Ham National Rehabilitation Center Donghwan Hwang National Rehabilitation Center Suncheol Kwon National Rehabilitation Center Joon-Ho Shin (  asfreelyas@gmail.com ) https://orcid.org/0000-0001-6447-8829
Does economic inequality affect electoral participation?

This master’s thesis explores the potential effect of income inequality on political participation in advanced democracies. Different theoretical models stipulate both positive and negative effects, although previous research has either found evidence of a negative effect or no effect at all. This paper contributes to the literature by conducting multi-level econometric analyses of the relation between electoral participation and various income inequality measures. Two datasets are used in the study; the first is an aggregate-level panel dataset and the second consists of post-election survey data with information on the individual level. The results are mixed; some models indicate that income inequality is negative for turnout rates across all income groups, yet, other models find no statistically significant effect. The thesis argues that future research should place weight on separating the effects of income and income inequality on participation. 1The author wishes to thank Ryszard, Karl-Oskar, Pär, Julian and Jenny for helping to complete this thesis.
Effect of sulphur on growth and yield attributes of sugarcane in sulphur deficient soils of Kaalaiyarkovil block of Sivagangai district

A field experiment was conducted with twelve treatments to evaluate the effect of sulphur on growth, yield attributes and yield of sugarcane in a sulphur-deficient soil series of Kaalaiyarkovil block in Sivagangai district, during the year 2018. The results revealed that the application of sulphur @ 100 kg ha -1 as soil application in the form of FeSO 4 along with STCR based NPK recommendation registered the maximum growth and yield attributes and cane yield (155.00 tonnes ha -1 ), followed by T 12 (150.00 tonnes ha -1 ). However, they were statistically on par with each other.
GEOMETRICALLY-BASED HYPOTHESIS TESTING FOR TOPOLOGY ERROR IDENTIFICATION

This paper presents a topology error identifica- tion algorithmcapable ofprocessing networks modeled at sub- station level. The methodology is based on hypothesis testing, which assumes that the set of switching devices is partitioned into suspect and true subsets by examining the magnitude of normalized Lagrange multipliers. To improve the efficiency of the method, a cosine test based on the geometric interpreta- tion of the Lagrange multiplier si s developed and included in the algorithm. The proposed geometrically-based test proves to be instrumental to ensure good performance of the identifi- cation method, as confirmed by several simulations conducted on the IEEE 30-bus network.
Reanalysis of the Atmospheric Radiocarbon Record from Lake Suigetsu for Radiocarbon Calibration

Terrestrial plant macrofossils from the sedimentary record of Lake Suigetsu, Japan, provide the only quasi-continuous direct atmospheric record of radiocarbon covering the last 50 ka cal BP (Bronk Ramsey et al. 2012). Since then, new high precision data have become available on UTh dated speleothems from Hulu Cave China, covering the same time range (Cheng et al. 2018). In addition an updated varve-based chronology has also been published for the 2006 core from Lake Suigetsu (SG06) based on extended microscopic analysis of the sediments and improved algorithms for interpolation (Schlolaut et al. 2018). Here we reanalyse the radiocarbon dataset from Suigetsu based on the new varve counting information and the constraints imposed by the speleothem data. This enables the new information on the calendar age scale of the Suigetsu dataset to be used in the construction of the consensus IntCal calibration curve. Comparison of the speleothem and plant macrofossil records provides insight into the mechanisms underlying the incorporation of carbon into different types of record and the relative strengths of different types of archive for calibration purposes.
A comparative study of efficacy of propofol auto co induction versus midazolam propofol co induction using the priming principle of

Background: Induction can be considered as one of the most crucial events in anaesthesiology and propofol is preferred induction agent nowadays due to its good properties. The aim of present study was to evaluate the clinical efficacy of propofol auto-co-induction compared to midazolam propofol co-induction in terms of: reduction in induction dose of propofol; and hemodynamic stability in peri-intubation period. Method: A total of 90 patients were randomly allocated into 3 groups of 30 each. Group I received the priming agent IV propofol 0.5mg/kg, group II received 0.05 mg/kg IV midazolam and group III received 3 ml of normal saline. This was followed by IV induction with propofol 2 minutes later in all the three groups till the loss of eyelash reflex. Results: Induction dose of propofol was significantly reduced in group II by 12.38% as compared to group I(5 %). After induction mean HR was significantly lower in group I as compared to group II and controls. Mean SBP and DBP was significantly higher in group II as compared to group I and controls in peri intubation period. While mean DBP of IV propofol group was lower than control group. Oxygen saturation was comparable among all three groups and maintained above 95% throughout the surgery. No complications were noted in any of the groups. Conclusion: The results showed a significant decrease in induction dose requirement in both the groups but dose reduction was significantly more with midazolam. Haemodynamic stability during induction and intubation was more in propofol auto-co-induction group.
Molecular Genetics of the flgI Region and Its Role in Flagellum Biosynthesis in Caulobacter crescentus

The differentiating bacterium Caulobacter crescentus has been studied extensively to understand how a relatively simple life form can govern the timing of expression of genes needed for the production of stage-specific structures. In this study, a clone containing the 5.3-kbflaP region was shown to contain theflgI, cheL, andflbY genes arranged in an operon with transcription proceeding fromflgI toflbY. The predictedflgI polypeptide shows remarkable identity (44%) to the flagellar basal body P-ring protein encoded by theflgI gene of Salmonella typhimurium. flgI mutations cause a reduction in the levels of flagellin production and the overproduction of the hook proteins. Therefore, theflgI-encoded P-ring protein is required for normal flagellin and hook protein synthesis, suggesting that basal body assembly may play a role in the regulation of flagellar gene expression. The flbY gene probably is a basal body component as well, since flbY mutants have flagellin and hook protein synthesis patterns similar to those exhibited by other basal body mutants. The smaller cheL gene complements a mutant that is unable to respond to chemotactic signals despite possessing a functional flagellum. This is the first example of an operon containing both flagellar and chemotaxis genes in C. crescentus.
Constraints on the formation of Yakutian eclogites derived from the crystal chemistry of iron in clinopyroxene and garnet

Clinopyroxene (cpx) and garnet are well known for their ability to incorporate large amounts of water (e.g., Bell and Rossmann, 1992). However systematic studies of the water content in these minerals have shown that the lowest concentrations are typically found in samples from the highest pressure regions, i.e., in diamond-bearing eclogite xenoliths (e.g., Matsyuk et al., 1998; Koch-Müller at al., 2004). Whether or not these low water concentrations indeed reflect conditions during eclogite formation, however, depends on factors such as the nature of hydrogen incorporation in the structures and how easily it is lost. Motivated by the importance (and challenge) of quantifying the nature of volatiles during eclogite formation, we are undertaking a systematic study of a suite of eclogite xenoliths from kimberlites to correlate major element concentrations, structural parameters, iron oxidation states, and hydrogen concentrations, in order to assess the degree to which these parameters were preserved during exhumation, and hence determine the likely conditions under which the eclogites were formed. Fig. 1. Variation of cation vacancy with H2O concentration in omphacitic cpx according to data reported by Smyth et al. (1991) (S91) and Katayama and Nakashima (2003) (KN03).
Heat Transfer Augmentation Based on Twin Impingement Jet Mechanism

Much of the research interest has now been conferred to jet impingement heat transfer mechanism, particularly in cooling related to electronic equipment and automotive engine since forced convection action generates high heat transfer coefficients. The paper aims to improve the heat transfer rate at radial position at a distant from the stagnation point. This is achieved by determining the local heat transfer coefficients by considering the aluminium plate surface, which employs the twin impingement jet mechanism likewise that allows capturing the distribution associated with heat transfer characteristic near the measured surface because there is not much information regarding this topic. This article presents the experimental studies regarding jet impingement heat transfer as well as associated measurements for local heat transfer coefficient. This subsequently resulted in determining the heat transfer rate associated with the impingement aluminium plate. In this research study, nine models with different parameters has been developed where the distance from nozzle to aluminium Plate (H) equal 10, 60 and 110 mm, while the spacing between nozzles (S) equal 10, 20 and 30 mm. At Reynolds number 10,000, measurements were done, and a heat flux micro-heat sensor installed away from the stagnation point from 0 to 140 mm at radial positions, was employed to measure the heat flux of the steadily heated air jet that impinged on the aluminium surface. The local heat transfer coefficients regarding steady air jet were calculated by measuring the heat flux. Thermal data are recorded, and Graphtec GL820 multichannel data logger was employed to capture distributions of heat transfer. The best heat transfer coefficient was observed through the results from the area enclosed between aluminium plate and nozzles and the closest distance between twin nozzles, particularly in the initial 5 points at the flat, which lowering as we start to move away from the aluminium plate centre. The temperature distribution at the front of aluminium foil Fluke Ti25 was recorded with the help of an infrared thermal imager.
The Influence of Budgeting Participation, Budget Target Clarity, Professionalism on Managerial Performance of Medan Local Work Unit

The objective of the research was to find out and to analyze the influence of Participation in Budget Preparation, Budget Target Clarity, and Professionalism partially on Managerial Performance in the SKPDs (Regional Work Units) of Medan Municipality. The research used causal method, and the objects of the research were all SKPDs in Medan. Primary data were gathered by distributing questionnaires to 56 SKPDs, using quantitative approach and analyzed by using SEM model. The result of the research showed that, partially, budget target clarity and professionalism had positive and significant influence on managerial performance in the SKPDs of Medan Municipality, while participation in Budget Preparation had positive but insignificant influence on Managerial Performance in the SKPDs of Medan Municipality .
Performance of spring maize varieties under varying plant rectangularity and fertility levels Performance of spring maize ( Zea mays L.) varieties under varying plant rectangularity and fertility levels

A field experiment was conducted during spring season of 2013 to study the effect of plant rectangularity varieties and fertility levels on growth, yield and quality of spring maize. Among spacing, S2 recorded significantly higher dry matter accumulation, number of grains/cob and 1000-grain weight than S1. Significantly higher grain and stover yield of spring maize was produced when planted at closer spacing 60×20 cm. PMH -1 recorded significantly higher plant height, dry matter accumulation, number of grains/cob, 1000-grain weight, grain and stover yield than JH-3459. Application of N 140 P 30.57 K 29.17 kg/ha being at par with N 120 P 26.20 K 25 kg/ha which produced significantly higher plant height, dry matter accumulation, number of grains/cob, 1000-grain weight, grain and stover yield than N 80 P 17.47 K 16.67 kg/ha and N 100 P 21.83 K 20.83 kg/ha. However, the protein content was found higher in N 140 P 30.57 K 29.17 kg/ha level, which was at par with N 120 P 26.20 K 25 kg/ ha level, whereas starch content was significantly higher in N 80 P 17.47 K 16.67 kg/ha.
Attosecond-Resolved Electron Dynamics in Many-Electron Atoms: Quantitative Theory and Comparison with Measurements

A variety of processes originating from the interaction of atomic or molecular N-electron states with strong and/or hypershort radiation pulses can be understood quantitatively only by first determining with good accuracy the solutions of the many-electron time-dependent Schrodinger equation (METDSE) that describe the corresponding physics. The METDSE is solvable nonperturbatively via the state-specific expansion approach (SSEA). SSEA solutions have been used, or can be used, for quantitative explanation and numerically reliable predictions of quantities that have been measured or are measurable in modern laser-driven experiments that can track, with hypershort (attosecond) time resolution, the effects of electron rearrangements in atoms and molecules. The calculations take into account in a transparent way the interplay between the phenomena and the electronic structures of the physically significant states in discrete and multichannel continuous spectra, including multiply- and inner-hole–excited resonance states. The discussion focuses on novel topics of time-resolved many-electron physics and includes a comparison of our predictions to recent quantitative measurements of attosecond-resolved generation of the profile of the ( 2 s 2 p ) 1 P o doubly excited resonance state of helium during photoionization and of the relative time delay in photoemission of the (2s,2p) electrons of neon.
EFFECTS OF PHYSICAL ACTIVITY ON THE QUALITY OF LIFE IN WOMEN WITH OVERWEIGHT AND POST MENOPAUSAL OBESITY

This study aimed to analyze the impact of a physical exercise program adapted to the reality of the Family Health Units (FHUs), about Quality of Life (QoL) in women with overweight and obesity in postmenopausal. This is a descriptive, cross-sectional quantitative research conducted in FHU in a Midwestern city of São Paulo, Brazil. A convenience sample consisted of 68 postmenopausal women with overweight and obese equally and randomly allocated to the exercise group and the control group. The exercise program was based on the recommendations of the American College of Sports Medicine which is adapted to the conditions available at FHU. For data analysis it was used descriptive statistics and statistical parametric and nonparametric, with α set at 0.05. In the exercise group was found domains significantly higher than in the control group for the domains functional capacity, physical aspects, pain, general health, mental health and general perception of quality of life. The condition of health is determined by multiple factors and can be monitored by different indicators. QoL has performed an important indicator of the health condition due to its impact on the autonomy to carry out daily activities of postmenopausal women.
Spatio-temporal water quality assessment of the wetlands in the lower part of Gilgel Abay River Catchment, Ethiopia

This study was conducted in the wetlands of the lower Gilgel Abay River catchment, Ethiopia from 2017 to 2018. The objective of the study was to assess the impacts of human activities on the physicochemical parameters and habitat quality of the wetlands. The water quality parameters (temperature, pH, salinity, TDS, TSS, DO, turbidity, electrical conductivity and nutrients) were examined at six study sites during the wet and dry seasons. The significance of spatial and temporal variability of water quality parameters was evaluated using Kruskal-Wallis and Mann-Whitney U tests respectively. The result showed that most of the water quality parameters were significantly different among the sampling sites and between seasons ( p < 0.05). The water quality parameter association using principal component analysis (PCA) indicated that the quality of water was influenced by human activities such as agricultural activities and urban effluent around the wetland. The study concluded that the wetlands have been polluted as a result of the human activities within the wetlands and their surrounding areas. It is recommended that the unsustainable human activities around the wetlands should be minimized to reduce further deterioration.
Research on the prevalence of COX-2 gene promoter -765G>C polymorphism, inflammation, and serum levels of PGE 2 in coronary artery disease

Cyclooxygenase-2 (COX-2) is an enzyme involved in the production of prostaglandins during inflammation. The aim of this study was to investigate the prevalence of COX-2 gene promoter -765G>C polymorphism in a Greek adult population in relation to coronary artery disease. In total, 102 subjects, 74 men (72.55%) and 28 women (27.45%) (median (range) 55 (36-86) years of age) were recruited. Subjects were divided into two main groups: 69 patients (67.65%) hospitalized for myocardial infarction (MI), 54 (78.26%) of which with elevated ST (STEMI) and 15 (21.74%) without (NSTEMI) (study group). The second group consisted of 33 patients (32.35%) with unstable angina but no history of MI (controls). Serum levels of highly sensitive C-reactive protein (hsCRP) and prostaglandin E 2 (PGE 2 ) and COX-2 -765G>C gene promoter polymorphism were determined. Genotype frequencies were 60% for CC, 22% for GC and 18% for GG in the total of subjects participating. Although there were statistically significant higher hsCRP levels in study group than controls (p<0.001), there were no significant differences in serum levels of hsCRP (p=0.807 and 0.893) or PGE 2 (p=0.455 and p=0.303) between different genotypes in either group, respectively. The onset of acute coronary events does not seem to be related to the -765G (cid:1)(cid:1)(cid:1)(cid:1) C polymorphism of the COX-2 gene promoter.