Miracle-dz/UniFAR-FTUs huggingface dataset:
Relationship between structural brainstem and brain plasticity and lower-limb training in spinal cord injury: a longitudinal pilot study

Rehabilitative training has shown to improve significantly motor outcomes and functional walking capacity in patients with incomplete spinal cord injury (iSCI). However, whether performance improvements during rehabilitation relate to brain plasticity or whether it is based on functional adaptation of movement strategies remain uncertain. This study assessed training improvement-induced structural brain plasticity in chronic iSCI patients using longitudinal MRI. We used tensor-based morphometry (TBM) to analyze longitudinal brain volume changes associated with intensive virtual reality (VR)-augmented lower limb training in nine traumatic iSCI patients. The MRI data was acquired before and after a 4-week training period (16–20 training sessions). Before training, voxel-based morphometry (VBM) and voxel-based cortical thickness (VBCT) assessed baseline morphometric differences in nine iSCI patients compared to 14 healthy controls. The intense VR-augmented training of limb control improved significantly balance, walking speed, ambulation, and muscle strength in patients. Retention of clinical improvements was confirmed by the 3–4 months follow-up. In patients relative to controls, VBM revealed reductions of white matter volume within the brainstem and cerebellum and VBCT showed cortical thinning in the primary motor cortex. Over time, TBM revealed significant improvement-induced volume increases in the left middle temporal and occipital gyrus, left temporal pole and fusiform gyrus, both hippocampi, cerebellum, corpus callosum, and brainstem in iSCI patients. This study demonstrates structural plasticity at the cortical and brainstem level as a consequence of VR-augmented training in iSCI patients. These structural changes may serve as neuroimaging biomarkers of VR-augmented lower limb neurorehabilitation in addition to performance measures to detect improvements in rehabilitative training.
The kinematics, dynamics, and control of free-flying and free-floating space robotic systems

Some important dynamics and control problems unique to space robotic systems are discussed. Particular attention is paid to free-flying and free-floating space robots that might be used for such tasks as space station repair and construction. Advances in solving these problems are briefly reviewed. Three promising methods for planning and controlling the motion of space robotic systems are presented. It is suggested that a thorough understanding of the fundamental dynamics of these systems will result in effective solutions to their control problems. >
Phenes of water frogs (Pelophylax) as the indicators of water bodies’ contamination in Pre-Carpathians, Roztochia, LESSER and Western Polissia

The results of phenotypic variability of water frogs ( Pelophylax ) analysis depending on internal and external influence factors are presented. 345 individuals of three species (Marsh Frog, Pool Frog and Edible Frog) were taken for the analysis from water bodies of different level of anthropogenic influence. The hydrochemical composition of water from the investigated aquatic ecosystems was analyzed, and the classification of water bodies after their water quality was done. The expression rates of nine phenotypes depending on the species of frog, its age stage and water quality class were established. It was found out that all the analyzed phenes show a significant dependence on the habitat conditions. The expression rates of middorsal stripe, as well as the coloration of femur and tibia depend mostly on water bodies’ contamination level. The increasing level of chemical contamina­ tion changes the ratios of alternative variants of middorsal stripe, and coloration of femur and tibia. New variants in coloration of femur and tibia that have never been described were noticed. Pelophylax individuals from the most contaminated water bodies (Cholgyni, Perekalky and Zhovtantsi) showed the highest variability by the analyzed phenes.
Controller Design for Robot with Pneumatic Artificial Muscles

This paper addresses a control issue of a robot with antagonistic McKibben artificial muscle. It is already shown that antagonized arrangement cancels some disadvantages of McKibben muscles. It also realizes control of both joint stiffness and joint torque. This study proposes a novel method to improve control bandwidth by adjusting joint stiffness. Joint stiffness is manipulated according to requested specification such as control bandwidth and compatibility to human. Experimental results verify the validity of the proposed method
Continental anthropogenic primary particle number emissions

Abstract. Atmospheric aerosol particle number concentrations impact our climate and health in ways different from those of aerosol mass concentrations. However, the global, current and future anthropogenic particle number emissions and their size distributions are so far poorly known. In this article, we present the implementation of particle number emission factors and the related size distributions in the GAINS (Greenhouse Gas–Air Pollution Interactions and Synergies) model. This implementation allows for global estimates of particle number emissions under different future scenarios, consistent with emissions of other pollutants and greenhouse gases. In addition to determining the general particulate number emissions, we also describe a method to estimate the number size distributions of the emitted black carbon particles. The first results show that the sources dominating the particle number emissions are different to those dominating the mass emissions. The major global number source is road traffic, followed by residential combustion of biofuels and coal (especially in China, India and Africa), coke production (Russia and China), and industrial combustion and processes. The size distributions of emitted particles differ across the world, depending on the main sources: in regions dominated by traffic and industry, the number size distribution of emissions peaks in diameters range from 20 to 50 nm, whereas in regions with intensive biofuel combustion and/or agricultural waste burning, the emissions of particles with diameters around 100 nm are dominant. In the baseline (current legislation) scenario, the particle number emissions in Europe, Northern and Southern Americas, Australia, and China decrease until 2030, whereas especially for India, a strong increase is estimated. The results of this study provide input for modelling of the future changes in aerosol–cloud interactions as well as particle number related adverse health effects, e.g. in response to tightening emission regulations. However, there are significant uncertainties in these current emission estimates and the key actions for decreasing the uncertainties are pointed out.
Birmingham Mid-Head Resection Periprosthetic Fracture

Total hip arthroplasty in the young leads to difficult choices in implant selection. Until recently bone conserving options were not available for younger patients with deficient femoral head bone stock. The novel Birmingham Mid-Head Resection (BMHR) device offers the option of bone conserving arthroplasty in spite of deficient femoral head bone stock. Femoral neck fracture is a known complication of standard resurfacing arthroplasty and is the most common reason for revision. It is unknown whether this remains to be the case for the BMHR neck preserving implants. We report a case of a 57-year-old male, who sustained a periprosthetic fracture following surgery with a BMHR arthroplasty. This paper illustrates the first reported case of a BMHR periprosthetic fracture. The fracture pattern is spiral in nature and reaches to the subtrochanteric area. This fracture pattern is different from published cadaveric studies, and clinicians using this implant should be aware of this as revision is likely to require a distally fitting, rather than a metaphyseal fitting stem. We have illustrated the surgical technique to manage this rare complication.
Feature-preserving regularization method for complex-valued inverse problems with application to coherent imaging

We propose a method for feature-preserving regularized reconstruction in coherent imaging systems. In our framework, image formation from measured data is achieved through the minimization of a cost functional, designed to suppress noise artifacts while preserving features such as object boundaries in the reconstruction. The cost functional includes nonquadratic regularizing constraints. Our formulation effectively deals with the complex-valued and potentially random-phase nature of the scattered field, which is inherent in many coherent systems. We solve the challenging optimization problems posed in our framework by developing and using an extension of half-quadratic regularization methods. We present experimental results from three coherent imaging applications: digital holography, synthetic aperture radar, and ultrasound imaging. The proposed technique produces images where coherent speckle artifacts are effectively suppressed, and important features of the underlying scenes are preserved.
Software Architecture Recovery of Embedded Software

The complexity of embedded software systems has increased substantially in the last years. The concept of software architecture provides methods and notations to handle the increased size and complexity. These concepts provide a higher level of abstraction than common analysis and design methods. The architecture of existing legacy systems is of high interest for the development of successors of such systems. However, architectural information of legacy systems is often not available. The architecture recovery process we discuss is research work within the ESPRIT project ARES (Architectural Reasoning for Embedded Systems). 1
Organizing for Product Development Across Technological Environments: Performance Trade-offs and Priorities

This study examines how designing for product development influences project performance in distinct technological environments. Drawing on a series of computational experiments and paired-case comparisons of six product development projects, we specifically examine how new product development performance is affected by project design and the technological environment. By triangulating across the computational experiments and case studies, we find the existence of performance trade-offs in product development as well as the importance of performance priorities in influencing project design. These findings permit us to elaborate on existing contingency-based perspectives of new product development and put forward a novel mediating model. In this mediating model of product development, we suggest that the technological environment shapes performance priorities, which in turn influence project design and ultimately the performance outcomes of new product development efforts. This model further highlights that project designs can evolve as a function of performance outcomes, although this process can be inhibited by the presence of design evolution constraints. This research contributes significantly to our understanding of designing projects for new product development.
The effect of a deproteinized bovine bone mineral on bone regeneration around titanium dental implants.

The aim of the present experiment was to test the effect of a deproteinized bovine bone mineral (Bio-Oss) on guided bone regeneration (GBR) in dehiscence defects around implants. The first 2 molars and all premolars were extracted on both sides of the mandibles of 3 monkeys (Macaca fascicularis). Three months later, 2 titanium plasma-coated cylindrical implants were placed in all quadrants of each monkey. During the surgical procedure, standardized dehiscence defects were produced buccally and lingually, measuring 2.5 mm in width and 3 mm in height. Four different experimental situations were created: 2 sites in each monkey were covered with an ePTFE membrane (M), 2 were filled with the graft material (DBBM), 2 were filled with the graft material and also covered with a membrane (M + DBBM), and 2 control sites were neither grafted nor covered (C). The flaps were sutured to allow for primary healing. Linear measurements of bone height and width were calculated on histological specimens obtained 6 months following surgery. In addition, values for bone density and for surface fraction of graft to new bone contact were measured. Vertical bone growth along the implant surface of 100% (SD 0%) for M + DBBM, 91% (SD 9%) for M, 52% (SD 24%) for DBBM, and 42% (SD 35%) for C was measured. The width of the regenerated bone 1.5 mm above the bottom of the original defect, i.e. at the 50% mark of the vertical extension of the defect, in relation to the width at the bottom of the defect amounted to 97% (SD 2%) for M + DBBM, 85% (SD 9%) for M, 42% (SD 41%) for DBBM, and 23% (SD 31%) for C. Assessment of bone density within the confinement of the regenerated bone resulted in an increase of 30% (SD 11%) for M + DBBM, 45% (SD 20%) for M, 33% (SD 20%) for DBBM, and 22% (SD 23%) for C. The values for graft to new bone contact within this compartment amounted to 80% (SD 15%) for M + DBBM and 89% (SD 14%) for DBBM. In conclusion, Bio-Oss exhibited osteoconductive properties and hence can be recommended for GBR procedures in dehiscence defects with respect to vertical and horizontal growth of bone.
Detecting the origin of text segments efficiently

In the origin detection problem an algorithm is given a set S of documents, ordered by creation time, and a query document D. It needs to output for every consecutive sequence of k alphanumeric terms in D the earliest document in $S$ in which the sequence appeared (if such a document exists). Algorithms for the origin detection problem can, for example, be used to detect the "origin" of text segments in D and thus to detect novel content in D. They can also find the document from which the author of D has copied the most (or show that D is mostly original.) We concentrate on solutions that use only a fixed amount of memory. We propose novel algorithms for this problem and evaluate them together with a large number of previously published algorithms. Our results show that (1) detecting the origin of text segments efficiently can be done with very high accuracy even when the space used is less than 1% of the size of the documents in $S$, (2) the precision degrades smoothly with the amount of available space, (3) various estimation techniques can be used to increase the performance of the algorithms.
Database as Symbolic Form

After the novel, and subsequently cinema, privileged narrative as the key form of cultural expression of the modern age, the computer age introduces its correlate - database. Many new media objects do not tell stories; they don't have a beginning or end; in fact, they don't have any development, thematically, formally or otherwise which would organise their elements into a sequence. Instead, they are collections of individual items, where every item has the same significance as any other. Why do new media favour database form over others? Can we explain its popularity by analysing the specificity of the digital medium and computer programming? What is the relationship between database and another form, which has traditionally dominated human culture - narrative? In addressing these questions, the article discusses the connection between the computer's ontology - the way the computer's organisation of data represents the world - and the new cultural forms privileged by computer culture such as database. Saussure's notions of the paradigm and the syntagm are used to theorise the relationship between database and narrative. A possible history of a database form in modern media and culture in general is sketched. The last part of the article addreses the tension between database and narrative in the history of cinema. It considers the works of such filmmakers as Peter Greenaway and Dziga Vertov as part of the tradition which can be called 'database cinema'. This cinema tries to merge databases and narrative into a new form, thus anticipating one of the key problems of new media art.
A Novel Human Tissue-Engineered 3-D Functional Vascularized Cardiac Muscle Construct

Organ tissue engineering, including cardiovascular tissues, has been an area of intense investigation. The major challenge to these approaches has been the inability to vascularize and perfuse the in vitro engineered tissue constructs. Attempts to provide oxygen and nutrients to the cells contained in the biomaterial constructs have had varying degrees of success. The aim of this current study is to develop a three-dimensional (3-D) model of vascularized cardiac tissue to examine the concurrent temporal and spatial regulation of cardiomyogenesis in the context of postnatal de novo vasculogenesis during stem cell cardiac regeneration. In order to achieve the above aim, we have developed an in vitro 3-D functional vascularized cardiac muscle construct using human induced pluripotent stem cell-derived embryonic cardiac myocytes (hiPSC-ECMs) and human mesenchymal stem cells (hMSCs). First, to generate the prevascularized scaffold, human cardiac microvascular endothelial cells (hCMVECs) and hMSCs were co-cultured onto a 3-D collagen cell carrier (CCC) for 7 days under vasculogenic culture conditions. In this milieu, hCMVECs/hMSCs underwent maturation, differentiation, and morphogenesis characteristic of microvessels, and formed extensive plexuses of vascular networks. Next, the hiPSC-ECMs and hMSCs were co-cultured onto this generated prevascularized CCCs for further 7 or 14 days in myogenic culture conditions. Finally, the vascular and cardiac phenotypic inductions were analyzed at the morphological, immunological, biochemical, molecular, and functional levels. Expression and functional analyses of the differentiated cells revealed neo-angiogenesis and neo-cardiomyogenesis. Thus, our unique 3-D co-culture system provided us the apt in vitro functional vascularized 3-D cardiac patch that can be utilized for cellular cardiomyoplasty.
Stereo Panning Features for Classifying Recording Production Style

Recording engineers, mixers and producers play important yet often overlooked roles in defining the sound of a particular record, artist or group. The placement of different sound sources in space using stereo panning information is an important component of the production process. Audio classification systems typically convert stereo signals to mono and to the best of our knowledge have not utilized information related to stereo panning. In this paper we propose a set of audio features that can be used to capture stereo information. These features are shown to provide statistically important information for non-trivial audio classification tasks and are compared with the traditional Mel-Frequency Cepstral Coefficients. The proposed features can be viewed as a first attempt to capture extra-musical information related to the production process through music information retrieval techniques.
Comparison of ChromID Agar and Clostridium difficile Selective Agar for Effective Isolation of C. difficile from Stool Specimens

Background ChromID Clostridium difficile agar (IDCd; bioMérieux SA, France) is a recently developed chromogenic medium for rapid and specific isolation of C. difficile. We compared the performance of IDCd with that of Clostridium difficile Selective Agar (CDSA). Methods A total of 530 fresh stool specimens were collected from patients with clinical signs compatible with C. difficile infection, and cultures for C. difficile were performed on IDCd and CDSA. C. difficile colonies were identified by spore staining, odor, use of an ANI identification test kit (bioMérieux SA), and multiplex PCR for tcdA, tcdB, and tpi. Results The concordance rate between IDCd and CDSA was 90.6% (480/530). The positivity rates on IDCd on days 1 and 2 (55.6% and 85.0%, respectively) were significantly higher than those on CDSA (19.4% and 75.6%, respectively) (P<0.001 for day 1 and P=0.02 for day 2), but the detection rates on IDCd and CDSA on day 3 were not different (89.4% vs. 82.8%, P=0.0914). On day 3, the recovery rates for non-C. difficile isolates on IDCd and CDSA were 30.2% (160/530) and 22.1% (117/530), respectively (P=0.0075). Clostridium spp. other than C. difficile were the most prevalent non-C. difficile isolates on both media. Conclusions The culture positivity rates on IDCd and CDSA were not different on day 3 but IDCd may allow for rapid and sensitive detection of C. difficile within 2 days of cultivation.
Relationship-based access control policies and their policy languages

The Relationship-Based Access Control (ReBAC) model was recently proposed as a general-purpose access control model. It supports the natural expression of parameterized roles, the composition of policies, and the delegation of trust. Fong proposed a policy language that is based on Modal Logic for expressing and composing ReBAC policies. A natural question is whether such a language is representationally complete, that is, whether the language is capable of expressing all ReBAC policies that one is interested in expressing. In this work, we argue that the extensive use of what we call Relational Policies is what distinguishes ReBAC from traditional access control models. We show that Fong's policy language is representationally incomplete in that certain previously studied Relational Policies are not expressible in the language. We introduce two extensions to the policy language of Fong, and prove that the extended policy language is representationally complete with respect to a well-defined subclass of Relational Policies.
USING FORCED DORSIFLEXION AND SUPINATION

We investigated a new method of stress radiography of the subtalar joints using forced maximum dorsiflexion of the ankle in a supinated position. We measured transposition of the lateral process of the talus at the posterior subtalar joint in lateral views of normal amputated ankles, normal control subjects and patients with recurrent ankle sprains. The mean displacement in the control groups (n = 36) was 29.9%, significantly different from the 43.0% in patients with recurrent ankle sprains (n = 24). In the amputated specimens with intact ligaments movement was similar to that in normal subjects. Section of the calcaneofibular and the interosseous ligaments allowed much the same movement as in patients with recurrent ankle sprains. The new method is simple and useful for detecting subtalar instability.
Vulnerable, but strong: The spinal cord-injured patient during rehabilitation

A traumatic spinal cord injury affects the body to an extent that the patient requires the assistance of others to survive and recover. The rehabilitation phase puts the patient in a vulnerable position and involves a considerable amount of strength on the patient's part. The aim of this paper is to explore the vulnerability of the spinal cord patient and how this vulnerability connects to the necessary strength, as the patient struggles to survive the injury and get through the rehabilitation. The circumstances of 12 traumatic spinal cord-injured patients were observed in the rehabilitation unit and after discharge. A phenomenological–hermeneutic narrative approach applying Ricoeur's theory was used. Data were collected by field observation and interviews during the first 2 years after the spinal cord injury. The patient's strength during the rehabilitation was portrayed by their endurance and from their narratives of how they handled difficult situations. The patient's perception of vulnerability varied, and strength was mobilised as a response to the vulnerability to overcome the imbalance between demands and resources. Vulnerability should therefore refer to a person's experience of the situation rather than the person, as it may hinder the professionals’ open, explorative approach towards the person.