Miracle-dz/UniFAR-FTUs huggingface dataset:
Population Dynamics of Raphidiopsis raciborskii
and Cylindrospermopsin Concentration in Ea Nhai
Reservoir in Dak Lak Province, Vietnam

Raphidiopsis raciborskii is a globally distributed bloom-forming cyanobacterium and produces toxin cylindrospermopsin (CYN), which results in public and environmental health consequences. piece of evidence To understand their blooming dynamics and to identify the environmental factors that determine their success in the tropical reservoir, a monthly monitoring program was conducted from May April 2020. Variations in phytoplankton communities, environmental parameters (temperature, pH, dissolved oxygen, turbidity, dissolved inorganic nutrients) and CYN were simultaneously determined from a total of 36 samples in the Ea Nhai reservoir in Vietnam. The phytoplankton is composed of a dominant cyanobacteria community formed mainly by filamentous R. raciborskii with the biovolume of up to 66.8 mm 3 L -1 . PCA and Pearson correlation results showed the biovolume and variation of R. raciborskii in the Ea Nhai reservoir were mainly related to temperature and nutrients (N-NH 4 , P-PO 4 , TP, TN). Analysis of the toxins by ELISA demonstrated the presence of CYN in all water samples with an average value of 1.24 µg L -1 and it was significantly correlated with the biovolume of the invasive species R. raciborskii. The results of the HPLC analysis confirmed the production of CYN in nine isolated Raphidiopsis strains with concentrations ranging from 0.054 to 0.584 μg g -1 DW. The relatively high biovolume of R. raciborskii is level of CYN in the water and the capacity to produce CYN of the isolated R. raciborskii strains represent a potential threat to the public health and the life of domestic and wild animals in the reservoir catchment.
EFFECT OF IJARAH REVENUE, MUDHARABAH FINANCING AND THIRD-PARTY FUNDS ON THE PROFITABILITY OF ISLAMIC COMMERCIAL BANKS

This research aims to analyze and empirically test the influence of ijarah revenue, mudharabah financing and third-party funds to the profitability of ROA of Islamic Commercial Bank contained in the Financial Services Authority for the 2016-2020 period. The research method used is a quantitative research method because this study uses numbers with statistical calculations and aims to test the hypotheses that have been made. The independent variables in this study were ijarah revenue, mudharabah financing and third-party funds while the dependent variable in this study was profitability (ROA). The research population is Islamic banking registered with the Financial Services Authority (OJK) in 2016-2020, with sample selection using purposive sampling techniques. Therefore, data on the monthly financial statements of Islamic Commercial Banks were obtained which were summarized in the Islamic Banking Statistics for the period 2016-2020, so that 60 research samples were obtained. Data collection techniques in this research use documentation and literature studies. The data analysis techniques used in this study are descriptive statistics, multiple regression analysis, classical assumption tests, determination coefficient tests and hypothesis testing using the EViews 12 analysis tool. Test F results show that ijarah revenue, mudharabah financing and third-party funds simultaneously have a significant effect on profitability (ROA). Meanwhile, T test reveals that ijarah revenue partially had a positive and significant effect on profitability (ROA), while mudharabah financing partially had a negative and significant effect on profitability (ROA) and third-party funds partially had a positive and significant effect on profitability (ROA).
Transcriptome changes in ERGIC3-knockdown hepatocellular carcinoma cells: ERGIC3 is a novel immune function related gene

Objective The expression of ERGIC3 is increased in a variety of tumors and promotes the growth and metastasis of liver cancer, but the molecular mechanism needs to be further studied.In this study, we aimed to analyze the molecular mechanism of ERGIC3 regulating the proliferation of human hepatocellular carcinoma (HCC) SMMC-7721 cells using transcriptomics. Methods ERGIC3 was knocked down in SMMC-7721 cells by RNAi technique, and the expression of ERGIC3 was detected by Q-RT-PCR and Western Blot. RNA sequencing was performed in the Illumina HiSeq platform in the control group and the ERGIC3i group and bioinformatics methods were selected to analyze the data. Results The expression of ERGIC3 was reduced to 10% in SMMC-7721 cells by RNAi technique, and 176 genes were up-regulated and 34 genes were down-regulated in ERGIC3i group compared with the control group. Analysis of the pathways and biological processes that enrich the function of differentially expressed genes showed thatthese differentially expressed genes were mainly involved in vesicular transport, growth factors, PI3K-Akt, NOD-like, Jak-STAT, NF-kappa B and other protein kinase-coupled receptors mediated signal transduction pathways, tumor immune response, collagen-integrin receptor-actin axis, and miRNA pathways. More importantly, most of the significantly altered pathways were related to immunity. ERGIC3 may be a key immune-related gene. Conclusion Based on the transcriptomic analysis, the mechanism of ERGIC3 promoting the growth of HCC is link with the transport of growth factor receptor, cytokine receptor and collagen. Then it is involved in signal transduction pathways mediated by protein kinase-coupled receptors, PI3K-Akt, NOD-like, Jak-STAT and NF-kappa B. In particular, the mechanism is also involved in the ERGIC3-dependent immune pathways. ERGIC3 is a potential target for prevention and treatment of HCC.
Missed Opportunities for Vaccination and Associated Factors among Children Attending Primary Health Care Facilities in Cape Town, South Africa: A Pre-Intervention Multilevel Analysis

Despite the substantial efforts at ensuring universal access to routine immunisation services among children in South Africa, major gaps in immunisation coverage remain. This study assessed the magnitude of missed opportunities for vaccination (MOV) and associated factors among children aged 0–23 months attending primary health care (PHC) facilities in Cape Town. We used multilevel binomial logistic regression models to explore individual and contextual factors associated with MOV, with children aged 0–23 months at Level 1, nested within PHC facilities (Level 2). A total of 674 children and their caregivers were enrolled. MOV prevalence was 14.1%, ranging from 9.1% to 18.9% across sub-districts. Dose-specific MOV prevalence was highest for the second dose of measles vaccine (9.5%) and lowest for the first dose of rotavirus vaccine (0.6%). The likelihood of a child experiencing MOV was significantly associated with caregivers’ low level of education (Odds ratio (OR) = 3.53, 95% credible interval (CrI): 1.13–11.03), recent receipt of immunisation messages (OR = 0.46, 95%CrI: 0.25–0.87), shared immunisation decision making by both parents (OR = 0.21, 95%CrI: 0.07–0.62) and health facility staff number (OR = 0.18, 95%CrI: 0.06–0.61). The burden of MOV among children in Cape Town is influenced by individual and contextual factors, which provide important opportunities for quality improvement and broader strategies to improve routine immunisation service delivery.
Comprehension and use of UK nutrition signpost labelling schemes

This is the most comprehensive and robust evaluation of FOP nutrition signpost labelling published to date. It provides information on how FOP labels are used by shoppers in a retail environment; the extent to which they are accurately interpreted and the impact of the co-existence of the current range of FOP labels on comprehension. This aim of this research was to establish which FOP labelling scheme(s), or which combination of elements of schemes, best facilitate the accurate interpretation of key nutritional information by consumers such that they are enabled to make informed choices about the foods they purchase. The research addressed three key questions: (1) How well do individual signpost schemes (or elements of the schemes) enable consumers to correctly interpret levels of key nutrients? ; (2) How do consumers use FOP labels in real life contexts in the retail environment and at home? ; (3) How does the coexistence of a range of FOP label formats affect accurate interpretation of FOP labels?
Financial Planning for Retirement: The Mediating Role of Culture

The life expectancy rate of individuals worldwide has risen, and Saudi Arabia is not excluded. Rising long-life expectancy may jeopardize employees’ pensions and reduce the chances of adequate earnings and a decent life after retirement. Moreover, the number of employees, who have paid into pension funds and are now retired, has increased, indicating that pension funds are expected to decrease. Apart from the above, the level of financial literacy in Saudi Arabia was substandard. Therefore, the ultimate objective of this research is to examine the measurable factors that could impact employees in their financial planning for retirement (FPR). These factors comprise the employee’s financial literacy (FL), financial risk tolerance (FRT), and cultural factors based on the CWO model. Moreover, this study aims to investigate the mediating roles of culture in their relationship with financial planning for retirement. Primary data was collected during the COVID-19 pandemic from mid-July 2020 until the end of January 2021 using a non-probability convenience sampling approach involving 525 participants. The Structural Equation Modelling (SEM) technique was used to analyze the data. To determine the type of study variables, either a formative or reflective model of Confirmatory Tetrad Analysis (CTA-PLS) was used. The results show the significant influence of basic FL, FRT, and culture on FPR. Moreover, it shows the critical role of culture among those with advanced FL and FRT. Previous studies have examined FL and FRT in FPR without considering the effect of culture as a mediator.
Multisensor Data-Fusion-Based Gas Hazard Prediction Using DSET and 1DCNN for Underground Longwall Coal Mine

The combustible and noxious gases are among the prominent issues affecting the life and the mining operations of underground coal mines (UCMs). Commonly adopted hazard monitoring methodologies in UCM are fuzzy, rule-based systems, statistical methods, and other expert systems, but these models are not reliable for highly complex and nonlinear systems. The neural network’s ability to learn and create nonlinear relationships is beneficial to making hazard prediction models. Especially, convolutional neural networks (CNNs) auto feature extraction capabilities to make it more suitable for the task. But, UCM’s harsh and crucial environment may result in sensor malfunctioning and faults, giving rise to data uncertainty. Like other data-driven models, data uncertainty significantly affects CNN’s performance. This study involves designing an effective and reliable gas hazard monitoring system using a hybrid of Dempster–Shafer evidence theory (DSET)-based filter and one-dimensional CNN (1DCNN) classifier. The novelty of this study is the integration of DSET and 1DCNN to predict the UCM hazard more reliably, even in malfunctioning node scenarios. Inherent usage limitations on traditional communication techniques restrict the application of cloud-based machine learning (ML) methods and this study use novel edge implementation of the filter and the classifier using edge ML (EML) technology. The proposed model’s hazard classification accuracy is 99.6%, even in the faulty node scenarios, where the traditional approaches fail.
How Do Clinical Supervisors and Managers in Swedish Primary Care Perceive Their Opportunities to Meet the Learning Needs of Medical Students?

Introduction Primary health care centers (PHCCs) in Sweden are struggling to maintain a balance between increasing demands of service and supervision and learning activities for a growing number of students. We sought a deeper understanding of primary care physicians and managers behavioral intention towards supervising, and their perceptions of the structural preconditions and support needed. Methods The study combines two theoretical approaches, the Theory of Planned Behavior (TPB) and Social Practice Theory. A questionnaire with 22 items including an open-ended question was designed to collect quantitative and qualitative data and sent to clinical supervisors and managers at PHCCs in Southern Sweden. The aim was to map a) participants’ behavioral intention and perceived capacity to act to improve supervision and b) their perceptions of structural prerequisites and support needed to sustain and develop clinical supervision practice. Results A total of 181 questionnaires were returned, with a total response rate of 60.7%. Behavior predictors (attitudes, subjective norms, and perceived behavioral control) were positively correlated to behavioral intention towards supervising and building supervising competence. Three themes emerged from the content analysis of the qualitative data: ”Time and distribution”, ”Improved communication and support systems” and ”Elimination of structural barriers. ”. Discussion The manager and supervisor reports suggest that the intentions and capacity of individuals (individuals’ agency) is not a strong barrier to high-quality supervising and teaching in PHCC. Organizational preconditions for sustaining and developing supervision practice exist, and structural barriers for exercising agency could be eliminated according to PHCC managers and supervisors. However, a conclusion of our study from a practice theory perspective is that how and to what degree primary care physicians engage in supervision and competence building is determined by how the workplace – and the medical school – afford participation in supervision-related workplace activities. Improved communication between medical school, managers and supervising physicians and on-site faculty development integrated in daily clinical work were described as important facilitators of a favorable supervision and learning environment.
Flow Cytometry Analysis of Blood Large Extracellular Vesicles in Patients with Multiple Sclerosis Experiencing Relapse of the Disease

The number of people living with multiple sclerosis (MS) in developed countries is increasing. The management of patients is hindered by the absence of reliable laboratory tests accurately reflecting the disease activity. Extracellular vesicles (EVs) of different cell origin were reportedly elevated in MS patients. We assessed the diagnostic potential, with flow cytometry analysis, of fresh large EVs (lEVs), which scattered more light than the 590 nm silica beads and were isolated from the blood plasma of relapsing remitting MS patients. Venous blood was collected from 15 patients and 16 healthy controls (HC). The lEVs were isolated from fresh platelet-free plasma by centrifugation, labelled with antibodies and the presence of platelet (CD41+, CD36+), endothelial (CD105+), erythrocyte (CD235a+), leukocyte (CD45+, CD19+, CD3+) and phosphatidylserine (Annexin V+) positive lEVs was analyzed using standard flow cytometry. Cryo-electron microscopy was used to verify the presence of EVs in the analyzed plasma fractions. MS patients experiencing acute relapse had slightly reduced relative levels (% of positive lEVs) of CD105+, CD45+, CD3+, CD45+CD3+ or CD19+ labelled lEVs in comparison to healthy controls. An analysis of other markers or a comparison of absolute lEV counts (count of lEVs/µL) did not yield any significant differences. Our data do not support the hypothesis that the exacerbation of the disease in RRMS patients leads to an increased numbers of circulating plasma lEVs which can be monitored by standard flow cytometry.
The Notable Achievements and the Prospects of Bacterial Pathogen Genomics

Throughout the entirety of human history, bacterial pathogens have played an important role and even shaped the fate of civilizations. The application of genomics within the last 27 years has radically changed the way we understand the biology and evolution of these pathogens. In this review, we discuss how the short- (Illumina) and long-read (PacBio, Oxford Nanopore) sequencing technologies have shaped the discipline of bacterial pathogen genomics, in terms of fundamental research (i.e., evolution of pathogenicity), forensics, food safety, and routine clinical microbiology. We have mined and discuss some of the most prominent data/bioinformatics resources such as NCBI pathogens, PATRIC, and Pathogenwatch. Based on this mining, we present some of the most popular sequencing technologies, hybrid approaches, assemblers, and annotation pipelines. A small number of bacterial pathogens are of very high importance, and we also present the wealth of the genomic data for these species (i.e., which ones they are, the number of antimicrobial resistance genes per genome, the number of virulence factors). Finally, we discuss how this discipline will probably be transformed in the near future, especially by transitioning into metagenome-assembled genomes (MAGs), thanks to long-read sequencing.
Placed Riprap Deformation Related to Axial Load at Toe Support: Physical Modelling

Rockfill dams are hydraulic structures of major importance. They can be exposed to extreme flood events, in turn leading to overtopping. These phenomena erode and affect structural and geotechnical integrity, which in turn can cause dam breach. Ripraps are broadly used for rockfill dam protection against such erosion processes. For steep slopes, as the one considered in this study (S = 1:1.5, vertical: horizontal), understanding the riprap behavior during overtopping is an important issue to improve dam design and reinforcement techniques. In this work, datasets are obtained from five experimental models of placed riprap built on a rock filter layer in a flume, at the hydraulic laboratory of the Norwegian University of Science and Technology, Trondheim. The riprap stones were placed in an interlocking pattern with a metallic support at the toe. The models were subjected to successive and incremental overtopping discharges until their complete failure. A laser traverse system was used to measure the coordinates (3D) of individual marked riprap stones between each discharge increase. Six load cells located at the toe measured the imposed loads during the entire procedure. From the total load values, two different types of load contributions could be distinguished: the self-weight of the stones and the hydraulic load depending on the discharge level of the overflow. This article highlights the strong relation in each of the five tests between riprap stone displacements, axial reaction load values measured at the toe and overtopping discharges. Moreover, as demonstrated in previous works, a buckling deformation of the riprap layer was observed and described. The results demonstrate that as the hydraulic load induces 2D deformations of the riprap, a larger part of the riprap weight is supported at the toe. Thus, the measured axial load during overtopping arises both from the hydraulic load and from the load imparted due to the compaction of the riprap layer. This compaction effect induces an even greater load than the one imposed due to the hydraulic contribution. The results from this study are finally put into perspective with the Norwegian Water Resources and Energy Directorate recommendations for full scale dams and suggest the great resistance of supported riprap at the toe.
BIOECOLOGY AND ECONOMIC INJURY LEVELS (EIL) OF Dysdercus volkeri F (HETEROPTERA: PYRRHOCORIDAE) ON SUNFLOWER (Helianthus annuus L.) IN SAMARU ZARIA, NIGERIA.

B.Sc. AGRIC. (UDUS) 1995, M.Sc. CROP PROTECTION (ABU), 2004 A DISSERTATION SUBMITTED TO THE SCHOOL OF POST GRADUATE STUDIES, AHMADU BELLO UNIVERSITY, ZARIA IN PARTIAL FULFILMENT FOR THE AWARD OF DOCTOR OF PHILOSOPHY IN CROP PROTECTION DEPARTMENT OF CROP PROTECTION FACULTY OF AGRICULTURE, AHMADU BELLO UNIVERSITY ZARIA JANUARY, 2013
A Retrospective Study from a Single Center of 208 Patients with Unilateral Chronic Subdural Hematoma to Compare Outcomes Following Burr Hole Craniotomy and Hematoma Drainage Within 48 Hours and Between 48 Hours and 5 Days

Background This retrospective study from a single center aimed to compare patient outcomes following burr hole craniotomy (BHC) and hematoma drainage within 48 hours and between 48 hours and 5 days in 208 patients with unilateral chronic subdural hematoma (CSDH). Material/Methods Patients were divided into 2 groups according to the duration of drainage: early (1 or 2 days, n=100) and late (3–5 days, n=108) drain removal. We compared the clinical outcomes, recurrence rate, time to recurrence, and complications between the groups. Quantitative analysis of computed tomography parameters at various time points (postoperative, day of drain removal, and postoperative day 7) was also performed to compare radiologic outcomes. Results Clinical outcomes and recurrence rate were similar in both groups. We found no significant differences in radiologic outcomes of both groups through all chronologies, although the total drainage volume was significantly greater in the late removal group (P<0.001). The incidence of surgical complications was significantly higher in the late drain removal group (8% vs 22.2%, P=0.007). Specifically, contralateral subdural effusion (CSE) tended to occur more frequently in the late removal group (2% vs 8.3%, P=0.038). Conclusions Following BHC and hematoma drainage for unilateral CSDH, maintaining the subdural drain for more than 48 hours did not improve patient outcomes or reduce the recurrence of hematoma, but increased the surgical complications, including CSE.
The effect of pregnancy and the occurrence of some biochemical changes during the first months of women in the city of Samarra

This study dealt with the effect of pregnancy on the biochemical blood characteristics, where blood samples were collected from pregnant women during the three stages of pregnancy and from married women who were not pregnant as a control group. A woman. As for married women who are not pregnant, they reached (10) women, their ages ranged between (15-40) years. The results of this study showed that the BMI of pregnant women increased as the pregnancy progressed compared with the non-pregnant married women at a significant level (P < 0.01). And it showed a significant increase in the concentration of cholesterol, triglycerides, and serum albumin concentration for pregnant women compared with married non-pregnant women at a significant level (P < 0.01).
Pelvic Fractures—An Underestimated Problem? Incidence and Mortality Risk after Pelvic Fracture in Austria, 2010–2018

(1) Background: Pelvic fractures (PFs) are related to osteoporosis, and represent a serious individual and socioeconomic burden. (2) Methods: We examined age- and sex-standardised incidence rates (SIRs) of PF, along with rates of all-cause overall and one-year mortality among patients with PF. We compared the mortality rates between PF patients and a matched fracture-free cohort. Patients ≥50 years old in Austria hospitalised with PF in 2010–2018, along with their dates of death, were recorded. (3) Results: We identified 54,975 patients with PF, of whom 70.9% were women. Between 2010 and 2018 the SIR of PF increased in men by 10.0%—from 125.3 (95% Confidence Interval 118.9–132.0) to 137.8 (95% CI 131.8–144.0) per 100,000—and in women by 2.7%—from 218.7 (95% CI 212.0–225.6) to 224.7 (95% CI 218.3–231.3) per 100,000. The one-year post-PF mortality rate was higher in men than in women (13.0% and 11.1%, respectively; p < 0.001). Pelvic fracture patients aged ≥65 had an elevated mortality risk (Hazard Ratio 1.75, 95% CI 1.71–1.79, p < 0.001) compared to controls. (4) Conclusions: There is a clear increase in the incidence of PF in the elderly population, with a greater increase in men over time. Pelvic fracture itself contributes to increased mortality in individuals aged 65 and above.