Miracle-dz/UniFAR-FTUs huggingface dataset:
Effect of High Intensity Interval Training and Honey Consumption on some Inflammatory Indices in Sedentary Subjects

Background: The sedentary lifestyle has been introduced as one of the main causes of disease and a predictor of morbidity and mortality. Inflammation is an essential contributor to the pathogenesis of diseases. The aim of the present study was to investigate the effect of high-intensity interval training and honey consumption on IL-6, IL-12 and TNF-a levels in sedentary individuals. Methods : Thirty-eight young, healthy and inactive men were assigned to one of the following interventions: Exercise+placebo (EP), Exercise+Supplement (ES), Supplement (S) and Placebo (P). Subjects in the exercise groups underwent a supervised HIIT program over 8 weeks. Exercise at each session comprised 2 min high intensity training with the intensity of 80-90% of heart rate max interspersed by low-intensity intervals of walking for 1 minute. Throughout the study, the subjects in supplement groups received 5 cc/kg body mass of 13% honey dissolved in plain water within 30-60 min before each exercise session. The subjects in placebo groups were administered with an equal volume of water solution with 5 gr sucrose. Before and 72h after the experimental period blood samples were collected to assess plasma levels of IL-6, IL-12, and TNF-a. Results : We observed that IL-6 levels significantly decreased in ES and E groups from pretest to posttest and there was a significant difference between the ES and control groups (Pvalue=0.023). However, no significant changes were observed for IL-12 and TNF-a (Pvalue> 0.05). Conclusions : HIIT program along with honey consumption over 8 weeks could have favorable effects on inflammatory indices such as IL-6 in subjects with sedentary life-style. Keywords : HIIT; honey; inflammation; IL-6; TNF-α; IL-12.
Submission to the UNFCCC Standing Committee on Finance-public

Since our founding over 30 years ago, SEI has been at the forefront of climate change research, connecting scientific findings and insights with practical policy advice. We support and advise decision-makers around the world grappling with, among other challenges, how to transition to a lowcarbon future and how to prepare for and adapt to the unavoidable impacts of climate change. We also have a portfolio of research and engagement work focused on climate finance, and on development finance more broadly.
Patterns of chemotherapy (CT) use in a population-based US-wide cohort of patients (pts) with metastatic pancreatic cancer (MPC).

4131 Background: Few population studies have examined the frequencies and durations of specific CT treatment regimens in MPC. Methods: We assessed 3,796 consecutive MPC pts who received CT between Jan 2005 and Aug 2013 at academic, private and community hospital-based practices participating in a US-wide CT order entry system that captures pt, provider and treatment data. Multivariate analyses of prospectively recorded pt and provider characteristics identified predictors of specific therapeutic approaches. Results: Among all pts, median age was 70; 55% male. In 1st-line CT, 48% of pts received gemcitabine (GEM) monotherapy, 16% received a GEM-based doublet (incl. GEM + nab-paclitaxel [NAB-P]), 9% received fluoropyrimidine (FU) + oxaliplatin (OX) + irinotecan (FOLFIRINOX), 9% received FU monotherapy, and 5% received FU + OX (FOLFOX). The remaining 13% received other regimens. GEM monotherapy use peaked at 58% in 2009 but declined to 28% in 2013. FOLFIRINOX use emerged in 2010 with 4% usage and peaked at 2.
Safety, clinical activity, and PD-L1 expression of avelumab (MSB0010718C), an anti-PD-L1 antibody, in patients with metastatic urothelial carcinoma from the JAVELIN Solid Tumor phase Ib trial.

367 Background: Avelumab* (MSB0010718C) is a fully human anti-PD-L1 IgG1 antibody being investigated in multiple clinical trials. We report safety and clinical activity of avelumab as a second-line therapy in patients (pts) with metastatic urothelial carcinoma (mUC) based on level of PD-L1 expression (NCT01772004). Methods: Pts with mUC unselected for PD-L1 expression received avelumab at 10 mg/kg Q2W by IV infusion until confirmed progression, unacceptable toxicity, or any criterion for withdrawal occurred. Tumors were assessed every 6 wks (RECIST 1.1). Best overall response rate (ORR) and progression-free survival (PFS) were evaluated. Adverse events (AEs) were graded by NCI-CTCAE v4.0. PD-L1 expression was assessed by immunohistochemistry. Results: As of 19 Mar 2015, 44 pts (30 men, 14 women) with mUC were treated with avelumab (median 13 wks [range 2-28]) and followed for a median of 3.5 mo (range 3.0-5.0). Median age was 68y (range 30-84), ECOG performance status was 0 (43.2%) or 1 (56.8%), and pts h.
SILVER OR GOLD ? SURPRISING CHALLENGES IN CLEANING A 19 TH-CENTURY PERSIAN WATER PIPE

Article: Silver or Gold? Surprising challenges in cleaning a 19th-century Persian water pipe Author(s): Ariel O’Connor, Meg Craft, Glenn Gates, and Julie Lauffenburger Source: Objects Specialty Group Postprints, Volume Twenty-Two, 2015 Pages: 151-168 Editors: Emily Hamilton and Kari Dodson, with Sarah Barack and Kate Moomaw, Program Chairs ISSN (print version) 2169-379X ISSN (online version) 2169-1290 © 2016 by The American Institute for Conservation of Historic & Artistic Works 1156 15th Street NW, Suite 320, Washington, DC 20005 (202) 452-9545 www.conservation-us.org
Real-Time Detection of Hemothorax and Monitoring its Progression in a Piglet Model by Electrical Impedance Tomography: A Feasibility Study

Hemothorax is a serious medical condition that can be life-threatening if left untreated. Early diagnosis and timely treatment are of great importance to produce favorable outcome. Although currently available diagnostic techniques, e.g., chest radiography, ultrasonography, and CT, can accurately detect hemothorax, delayed hemothorax cannot be identified early because these examinations are often performed on patients until noticeable symptoms manifest. Therefore, for early detection of delayed hemothorax, real-time monitoring by means of a portable and noninvasive imaging technique is needed. In this study, we employed electrical impedance tomography (EIT) to detect the onset of hemothorax in real time on eight piglet hemothorax models. The models were established by injection of 60 ml fresh autologous blood into the pleural cavity, and the subsequent development of hemothorax was monitored continuously. The results showed that EIT was able to sensitively detect hemothorax as small as 10 ml in volume, as well as its location. Also, the development of hemothorax over a range of 10 ml up to 60 ml was well monitored in real time, with a favorable linear relationship between the impedance change in EIT images and the volume of blood injected. These findings demonstrated that EIT has a unique potential for early diagnosis and continuous monitoring of hemothorax in clinical practice, providing medical staff valuable information for prompt identification and treatment of delayed hemothorax.
Learning to Adapt: A Swedish case study on adaptation of biodiversity management within Svenska Cellulosa Aktiebolaget (SCA)

Achieving adaptation within an organisation occurs largely through the process of organisational learning. The identification of organisational learning cycles and the factors that influence an organisation’s adaptation can improve understanding of how organisations adapt to complex sustainability issues. To date, efforts to analyse the factors that affect organisational adaptation have not been researched extensively within the Swedish forest industry. In order to address this gap, an operationalization of the organisational adaptation model in a case study of a Swedish forestry actor, Svenska Cellulosa Aktiebolaget (SCA), has been carried out. This study uses the model presented in Berkhout et al. (2006) on organisational adaptation to articulate the role of organisational learning in establishing and implementing adaptation measures for biodiversity management within SCA throughout the 1980s-1990s. It also identifies the factors that determined this process. There is evidence that two parallel organisational adaptation cycles occurred within SCA that shaped the emergence of two key adaptation options on biodiversity within the company, the Ecological Landscape Plan (ELP) and re-invention of SCA operations. Subsequently several factors were identified that affected this process of adaptation overtime including, mind-sets and values, employee skills, organisational culture and the context surrounding the company. This has implications for which adaptive measures may (or may not) be selected and carried out. Further research should be done to clarify which kind of innovations may be most effective to reduce the factors that act as barriers to organisational adaptation.
Epidemiology of small-bowel obstruction beyond the neonatal period

BackgroundThe aim of this study was to evaluate the etiologies causing intestinal obstruction beyond the neonatal period. Patients and methodsAn observational study was conducted on children between 1 month and 17 years of age who underwent surgery for small-bowel obstruction (SBO) at this tertiary referral center between 1 January 2004 and 31 December 2013. ResultsIn total, 133 patients (38 female) with a median age of 3.4 (range 0.16–15.8) years were included in the study group. Forty-four patients (18 female) had intussusception, of whom seven presented with a pathological lead point. Thirty-nine individuals (12 female) had a postoperative SBO. The median formation time for the SBO was 1.75 years, and neonatal anomalies represented the most frequent cause of initial surgery. Primary SBO with no previous surgery was observed in 30 children (eight girls), including 12 (9%) with Meckel’s diverticulum, nine (7%) with congenital bands, and three (2%) with bezoars.Twenty patients (15%), all boys, presented with an irreducible inguinal hernia. During the surgery, a total of 43 (32%) patients underwent bowel resection or enterotomy.Five patients (3.8%) died, four as a result of sepsis and one following parenteral nutrition-related liver failure. ConclusionNearly a quarter of this cohort had a primary SBO. SBO in children is more prevalent among boys (M : F ratio, 2.5 : 1). Intussusception, postoperative adhesions, and irreducible inguinal hernias are the most common pathologies for SBO, followed by Meckel’s diverticulum and congenital adhesive bands.
The Role of Attitude Toward Marketing and Marketing Practice on Marketing Performance: A Theoretical Framework Development for SMEs

Entrepreneurial marketing is known as implementation marketing in Small Medium sized Enterprises (SMEs). Many scholars investigated the entrepreneurial marketing issue in various contexts and environments. Previous studies found an inadequate marketing practice in SMEs. Then the research results concluded differences marketing practices between large size firms and SMEs. The nature of SME cause the behavior issue such as attitude toward marketing became one element that involve in marketing practice. The objective of this paper is to develop a conceptual model to improve marketing performance. This paper contributes to entrepreneurial marketing literature in exploring the influence of marketing attitude and marketing practice toward marketing performance. Keywords—Entrepreneurial Marketing, SME; Marketing Attitude
Effects of in ovo injection of nano-selenium and nano-zinc oxide and high eggshell temperature during late incubation on antioxidant activity, thyroid and glucocorticoid hormones and some blood metabolites in broiler hatchlings

This experiment was conducted to evaluate the effects of in ovo injection of nano-selenium (Nano-Se) and nano-zinc oxide (Nano-ZnO) and high eggshell temperature (EST) during late incubation on blood parameters of broiler hatchlings. A total of 750 fertile eggs, were weighed and randomly distributed among 5 treatment groups on each of 5 replicate tray levels. The injection was performed on 17 d of incubation. Treatments included of: 1) Eggs not injected and incubated at normal EST (control); 2) Eggs not injected and incubated at high EST; 3) Eggs injected NaCl solution and incubated at high EST (sham); 4) Eggs injected NaCl solution containing 40 μg Nano-Se and incubated at high EST; 5) Eggs injected NaCl solution containing 500 μg Nano-ZnO and incubated at high EST. EST of 37.8oC (normal) or 38.9oC (high) was applied from d 19 to 21 of incubation. In ovo injection of Nano-Se and Nano-ZnO significantly increased activity of GSH-Px and SOD and total protein, but decreased the levels of corticosterone, cortisol, T4 and T3 at high EST. Injection of Nano-Se and Nano-ZnO had a significant role in alleviating the negative effects of high temperature incubation and heat stress by increased antioxidant activity and reduced oxidative stress. Keyword: in ovo injection; Nano-selenium; Nano-zinc oxide; high eggshell temperature; blood. Received on December 28, 2018. Accepted on May 6, 2019.
Design and Fabrication of an Okra Threshing Machine

A simple Okra threshing machine was designed, fabricated and tested to alleviate the problems associated with Okra processing in Nigeria. It is consists mainly of five units namely, the feeding assembly, the threshing unit, separation unit, power transmission unit. The overall mean threshing and cleaning efficiencies obtained were 93.95 and 99.56% respectively. Drum speed 500rpm combine with 55mm concave clearance gave the highest Threshing efficiency of 99.99%. All speeds, concave clearance combinations gave clearing efficiency above 98%. The machine threshing and cleaning efficiencies increased with increase in drum speed and decrease with increase in concave clearance. The machine is simple to operate and maintain without formal training. © 2014 Elixir All rights reserved. ARTICLE INF O Artic le h istory: Received: 31 August 2014; Received in revised form: 20 September 2014; Accepted: 9 October 2014;
Spatio‐temporal distribution of sea turtle strandings and factors contributing to their mortality in south‐eastern Brazil

Data on stranded sea turtles were examined between 2010 and 2016 along the northern region of Rio de Janeiro state and between 2016 and 2017 in the southern region, looking for spatio‐temporal patterns and determining which factors contributed to their mortality. A total of 12,162 strandings of all five species that occur in Brazil were recorded, with Chelonia mydas being the most common (89.9%). Sea turtles use the Rio de Janeiro coast as a feeding and/or migration area. The intense upwelling (October to April) may be an important factor for the sea turtles feeding in this region, mainly for Eretmochelys imbricata and Dermochelys coriacea, which had a higher number of strandings during this period. Areas further north of the study area include an important nesting site for Caretta caretta in Brazil, which explains the higher concentration of strandings of subadults/adults of this species in this region and during its nesting season. Many anthropogenic threats to sea turtles were documented, mainly incidental capture in fisheries and marine debris, indicating possible hotspots for these threats in the regions of Sepetiba and Guanabara Bays, Cabo Frio, and Sao Francisco de Itabapoana. Among the natural causes of strandings, the primary factors were chronic illness, endoparasites, and fibropapillomatosis. However, pollution may also be an indirect threat, which negatively affects these animals through reduced health and immunosuppression, leaving them more susceptible to opportunistic diseases. These data are valuable for directing and implementing specific and local mitigation measures along the Rio de Janeiro state coast, such as avoiding bycatch hotspots through fleet communication programmes and/or area and seasonal closures, enforceable legislation, effective penalties and proper waste management.
Prevalence of Sports Practice among Mexican Adults in 2002 and 2014

espanolEl objetivo del estudio fue conocer el cambio en la prevalencia de la practica deportiva en adultos mexicanos y su asociacion con caracteristicas sociodemograficas. Analizamos la Encuesta Nacional de Uso del Tiempo (ENUT) de Mexico realizada en 2002 y 2014. A traves de un cuestionario se indago la practica deportiva en la semana previa. Las variables independientes fueron las caracteristicas sociodemograficas. Encontramos que la prevalencia de la practica deportiva aumento entre 2002 y 2014 (de 15.8% a 29.3%). Ser soltero o tener una posicion socioeconomica alta se asocio con una mayor probabilidad de practica deportiva. Los hombres y los habitantes de las ciudades tenian mayores probabilidades de practicar deporte en comparacion con sus contrapartes; aunque estas diferencias tendieron a disminuir. Concluimos que la prevalencia de la practica deportiva ha aumentado, sin embargo, sigue siendo baja. Identificamos grupos con menor probabilidad de practicar deportes en los que se pueden enfocar esfuerzos para promover la actividad fisica. EnglishThe aim of our study was to know the change over time of sports practice prevalence in Mexican adults and its socio-demographic correlates. We analyzed the Mexican National Survey of Time Use (ENUT) conducted in 2002 and 2014; which is based on a representative sample of Mexican adults. Through a questionnaire, it was inquired if people practised sport in the previous week of the interview and the time spent to do it. The independent variables were sociodemographic characteristics. We found that the prevalence of sports practice increased between 2002 and 2014 (from 15.8% to 29.3%). Being single or having a high socioeconomic position was associated with a higher probability of sports practice. Men and city dwellers had higher probabilities of practice sport compared with their counterparts; although these differences tended to decrease. We conclude that the prevalence of sports practice in Mexico has increased, but it remains low. We identified groups with lower probabilities to practice sport in which efforts can be focused to promote active lifestyles.
Biphasic Insulin Aspart 30 in Insulin Initiation

This case report concerns a patient with poor glycaemic control on oral antidiabetic drugs who initiated biphasic insulin aspart 30 (BIAsp 30), and reviews supporting clinical literature, alternative treatment choices and the options for intensification. During the six-month follow-up after initiation of BIAsp 30, glycosylated haemoglobin (HbA1c) was reduced from 10.2 % to 6.4 %, mean fasting blood glucose (FBG) was reduced from 9.0 mmol/l to 6.8 mmol/l and mean postprandial glucose (PPG) was reduced from 15.3 mmol/l to 8.8 mmol/l. Body weight increased by 4 kg. The patient experienced eight episodes of hypoglycaemia over the six-month period (four pre-lunch, one at bedtime and three nocturnal). The patient had six episodes with blood glucose (BG) <4.0 mmol/l but no episodes with BG <2.8 mmol/l. Insulin initiation with a premix insulin analogue offers a simple and convenient regimen of onceor twice-daily dosing and provides effective glycaemic control by providing coverage of both FBG and PPG.
Cinematic Representation of Chinese-Indonesians’ Trauma in Jason Iskandar The Day The Sky Roared

This research analyzed a contemporary independent Indonesian film entitled The Day the Sky Roared (2015) that was directed by Jason Iskandar. This 10-minute silent film talked about the anxiety of Chinese-Indonesians through the eyes of a mother and her daughter regarding the historical trauma of the May 1998 tragedy. The fact that the film was produced about 17 years after the tragedy suggested the director’s awareness that the trauma remained due to the absence of reconciliation and closure. This research would show how the short film frames the incident and trauma of the Chinese-Indonesians. The research was a combination of trauma studies and film studies that focuses on the visual analysis of the film’s cinematography and mise-en-scene to show the cinematic representation of Chinese-Indonesians’ trauma. The findings show that the portrayal of Chinese-Indonesians still strongly suggests unrelieved psychological discomfort, albeit, at different levels, that is closely related to the traumatic past and the pervasive stereotyping of Chinese-Indonesians.
The Afghan Community Health Worker Program: A Health Systems Analysis of a Population Health Intervention

To tackle one of the world’s worst maternal, neonatal and child health outcomes and a chronic shortage of human resources for health, the Afghan Ministry of Public Health deployed volunteer Community Health Workers (CHW) in rural areas of Afghanistan in 2003. This thesis documents the Afghan CHW program, exploring organizational and community contexts. The research design in this study is a mixed methods case study. The actual Afghan CHW program was situated with an Afghan complex adaptive health system, mainly guided by the policy of the health system but was also largely influenced by the power and gender dynamics of the community context in which it was implemented. The tasks of CHWs were numerous but CHWs role was more than just the sum of their tasks; they occupied a unique location juxtaposed between formal and informal HRH systems. It is important to acknowledge the assembly of so many national and international organizations in achieving a shared goal of providing health services to a large population in an unstable and partially insecure environment. The shared goal in the Afghan context may have been interpreted only in terms availability of services, though the goal carries with it, either explicitly or implicitly, the values of effectiveness, efficiency, timeliness, and costliness – known as quality by some participants of this study. The community component was another layer of the complex adaptive system that made up the Afghan CHW program. Political-ethnic power in the community and legal-rational authority of the health system influenced the way communities were mapped in an inequitable manner, in turn, contributed to the unfair distribution of resources to the populations. COMMUNITY HEALTH WORKERS OF AFGHANISTAN iii Finally, the intersection of the gender equity approach and the gendered nature of the work as a cross-cutting layer added to the complexity of the Afghan health system. COMMUNITY HEALTH WORKERS OF AFGHANISTAN iv
Refining victims’ self‐reports on bullying: Assessing frequency, intensity, power imbalance, and goal‐directedness

Bullying can be differentiated from other types of peer aggression by four key characteristics: frequency, intensity, power imbalance, and goal‐directedness. Existing instruments, however, usually assess the presence of these characteristics implicitly. Can self‐report instruments be refined using additional questions that assess each characteristic? We examined (a) what proportion of children classified as victims by the commonly used Revised Olweus’ bully/victim questionnaire (BVQ) also experienced the characteristics of bullying, and (b) the extent to which the presence of the characteristics was associated with emotional (affect, school, and classroom well‐being), relational (friendship, defending), and social status (popularity, rejection) adjustment correlates among victims. Using data from 1,738 students (Mage = 10.6; grades 5–8), including 138 victims according to the BVQ, the results showed that 43.1% of the children who were classified as victims by BVQ experienced all the four characteristics of bullying. Frequency ratings of victimization did not capture experiences that involved a power imbalance. Victims who reported all four key characteristics had greater emotional, relational, and social status problems than victims who did not report all characteristics. Thus, researchers who focus on victimization for diagnostic and prevention purposes can enrich self‐report measurements of bullying victimization by adding questions that assess the characteristics explicitly.