Miracle-dz/UniFAR-FTUs huggingface dataset:
Systèmes pair à pair pour la diffusion de données vidéo : PULSE, un système adaptatif pour le streaming en direct sur Internet

Le live streaming consiste en la distribution d’un flux de donnees multimedias (video et audio) en direct vers une large audience par le biais d’un reseau d’ordinateurs. L’approche traditionnelle client-serveur souffre d’un goulot d’etranglement au niveau de la bande passante remontante du serveur, dont la consommation augmente de facon lineaire avec le nombre d’usagers. Une approche pair-a-pair (P2P) a l’enorme avantage de permettre le passage a l’echelle du systeme jusqu’a une taille arbitraire, puisque chaque nœud qui recoit le flux video peut apporter ses ressources au reseau au meme temps qu’il en consomme. En theorie, au cas ou chaque nœud apporterait en moyenne la meme quantite d’upload qu’il consomme, le systeme pourrait s’accroitre indefiniment. Ce travail presente et evalue les performances de PULSE, un systeme de streaming en direct adapte aux exigences pratiques d’un deploiement a large echelle sur l’Internet. PULSE utilise un reseau maille non structure et applique des mecanismes locaux d’incitation au partage en tant que criteres pour le choix des nœuds avec qui etablir des associations. L’aspect le plus innovant de PULSE est l’introduction d’un mecanisme qui combine l’incitation avec une boucle de retroaction basee sur les delais de reception, qui mene a la formation de clusters parmi les nœuds qui partagent la meme quantite de ressources. Exploitant cette organisation emergente et utilisant des mesures de latence de bout en bout pour estimer la proximite entre nœuds, PULSE peut supporter un large eventail de scenarios reels ou les ressources sont rares et distribuees de facon heterogene, avec une large population d’usagers au comportement dynamique.
Lineshape of $e^+ e^-\to D^* \bar D+c.c.$ and electromagnetic form factor of $D^*\to D$ transition in the time-like region

In this work, we apply the vector meson dominance (VMD) model to extract the electromagnetic time-like form factor of the $D^*\to D$ transition combining the recent Belle data for $e^+ e^-\to D^{*+} D^- + c.c. $ and data for $D^*\to D\gamma$. Two solutions are obtained in the interpretation of the cross section lineshape: i) With a relatively large coupling for $\psi D^*\bar{D}$ determined by experiment, destructive interferences among those charmonium components are required to bring down the overall cross sections, and then account for the cross section lineshape. ii) With a relatively small value for the $\psi D^*\bar{D}$ coupling based on heavy quark theory, an apparent cross section deficit near threshold is observed, and contributions from other mechanisms are needed. It might imply the presence of an additional resonance X(3900). Meanwhile, we also point out that an enhancement like that could be produced by the $D_s^*\bar{D_s}+c.c. $ open channel effects.
CPC 47: NOVOS DIRECIONAMENTO OU UMA NOVA INTERPRETAÇÃO?

Em 2014, com o propósito de eliminar inconsistências e fragilidades das normas anteriores, o International Accounting Standards Board (IASB) e o Financial Accounting Standards Board (FASB) emitiram o IFRS 15 (ou Pronunciamento Técnico CPC 47 para empresas brasileiras) – Receita de Contrato com Cliente. Dentro deste contexto, o objetivo deste trabalho foi comparar o CPC 47 com o pronunciamento anterior, o CPC 30 – Receitas, para entender quais foram as mudanças apresentadas a partir da nova norma. Após análise teórica dos pronunciamentos, complementou-se a pesquisa com a análise das notas explicativas das empresas dos setores de Telecomunicações, Medicamentos e Outros Produtos e Material Aeronáutico e de Defesa, com o intuito de verificar quais os ajustes foram publicados por este grupo de empresas sob a justificativa da adoção do CPC 47. Adicionalmente, realizou-se a discussão do tema via focus group como forma de capturar a percepção dos ajustes decorrentes do CPC 47 vividos por especialistas da área contábil. Para a análise do resultado da discussão do focus group, utilizou-se a ferramenta NVivo® para a aplicação da metodologia análise de conteúdo como forma de minimizar possíveis inferências sobre o tema discutido. Os resultados mostraram que os ajustes capturados, tanto via nota explicativa, quanto focus group, estavam em sua maioria alinhados com as expectativas dos estudos teóricos. Com base na análise comparativa das normas, concluiu-se que a nova norma não apresentou alterações relevantes, entretanto, o fato de ter uma norma mais detalhada e/ou diretiva resulta em impactos na contabilidade das empresas.
Increased NMUR1 Expression in Mast Cells in the Synovial Membrane of Obese Osteoarthritis Patients

Obesity is a risk factor for knee osteoarthritis (KOA). Neuromedin U (NMU) and NMU receptors (NMUR1 and NMUR2) are associated with obesity-related disorders and found in mast cells (MCs), which are elevated in osteoarthritis. However, NMU/NMUR expression was not examined in the synovial membrane (SM) or synovial MCs of obese osteoarthritis patients. We compared expression of NMU, NMUR1, NMUR2, and the mast cell (MC) marker, CPA3, in the SM of KOA patients categorized as normal weight (NW; BMI < 25 kg/m2, n = 79), overweight (OW; BMI ≥ 25 and <30 kg/m2, n = 87), and obese (OB; ≥30 kg/m2, n = 40). To study NMU/NMUR expression in MCs, we compared the MC-rich fraction (MC-RF), CD88(+) MC-RF, and CD88(−) MC-RF, extracted using magnetic isolation, with the MC-poor fraction (MC-PF). While NMU and NMUR2 expression were comparable, NMUR1 was significantly elevated in OW and OB compared to NW. Moreover, CPA3 levels were significantly greater in OB than NW. NMUR1 and CPA3 expression were significantly higher in both the CD88(+) and CD88(−) MC-RF than MC-PF. Therefore, NMUR1 expression was elevated in the SM of OB KOA patients, and its expression was found in MCs. Further investigation to analyze the NMU/NMUR1 pathway in MC may provide a link between obesity and KOA pathology.
ANCHORING MAGNETIC FIELD IN TURBULENT MOLECULAR CLOUDS

One of the key problems in star formation research is to determine the role of magnetic fields. Starting from the atomic intercloud medium which has density nH ∼ 1 cm−3, gas must accumulate from a volume several hundred pc across in order to form a typical molecular cloud. Star formation usually occurs in cloud cores, which have linear sizes below 1 pc and densities nH2 > 105 cm−3. With current technologies, it is hard to probe magnetic fields at scales lying between the accumulation length and the size of cloud cores, a range corresponds to many levels of turbulent eddy cascade, and many orders of magnitude of density amplification. For field directions detected from the two extremes, however, we show here that a significant correlation is found. Comparing this result with molecular cloud simulations, only the sub-Alfvénic cases result in field orientations consistent with our observations.
Quantitative Assessment of Histone H2B Monoubiquitination in Yeast Using Immunoblotting

Studies in Saccharomyces cerevisiae and Schizosaccharomyces pombe have enhanced our understanding of the regulation and functions of histone H2B monoubiquitination (H2Bub1), a key epigenetic marker with important roles in transcription and other processes. The detection of H2Bub1 in yeasts using immunoblotting has been greatly facilitated by the commercial availability of antibodies against yeast histone H2B and the cross-reactivity of an antibody raised against monoubiquitinated human H2BK120. These antibodies have obviated the need to express epitope-tagged histone H2B to detect H2Bub1 in yeasts. Here, we provide a step-by-step protocol and best practices for the quantification of H2Bub1 in yeast systems, from cell extract preparation to immunoblotting using the commercially available antibodies. We demonstrate that the commercial antibodies can effectively and accurately detect H2Bub1 in S. cerevisiae and S. pombe. Further, we show that the C-terminal epitope-tagging of histone H2B alters the steady-state levels of H2Bub1 in yeast systems. We report a sectioned blot probing approach combined with the serial dilution of protein lysates and the use of reversibly stained proteins as loading controls that together provide a cost-effective and sensitive method for the quantitative evaluation of H2Bub1 in yeast.
Interactions between ZnO Nanoparticles and Polyphenols Affect Biological Responses

Zinc oxide (ZnO) nanoparticles (NPs) are used as a food additive Zn supplement due to the role of Zn in biological functions. They are directly added to complex processed foods or Zn-fortified functional foods. Hence, the interactions between ZnO NPs and nutritional or functional components can occur. In this study, the effects of ZnO NP interactions with two polyphenols (quercetin and rutin) on cytotoxicity, antioxidant activity, ex vivo intestinal absorption, and solubility were evaluated. Moreover, the characterization on the interactions was carried out by analyzing crystallinity, surface chemical bonding, chemical composition, and surface chemistry. The results demonstrate that the interactions caused higher cytotoxicity, ex vivo intestinal transport, and solubility of ZnO NPs than pristine ZnO NPs but did not affect antioxidant activity nor intestinal absorption of the polyphenols. The interaction effects were more evident by ZnO NPs interacted with quercetin than with rutin. The crystallinity of ZnO NPs was not influenced, but the degree of exposure of the chemical bondings, elemental compositions, and chemical group intensities on the surface of ZnO NPs, quercetin, or rutin were quenched or decreased to some extent by the interactions, especially by ZnO NPs interacted with quercetin. It is, therefore, concluded that the interactions affect chemical characteristics and surface chemical sates of ZnO NPs, quercetin, or rutin, which can cause high cytotoxicity, intestinal absorption, and solubility of ZnO NPs. Further study is required to elucidate the mechanism of action of the interactions.
Test Structure Design for Defect Detection during Active Thermal Cycling

Integrated power ICs acting as smart power switches for automotive or industrial applications are often subjected to active thermal cycling. Consequently, they undergo significant self-heating and are prone to various failure mechanisms related to the electro-thermo-mechanical phenomena that take place in the device metallization. In this article a test structure consisting of a lateral DMOS transistor equipped with several integrated sensors is proposed for metallization fatigue assessment. The design of the test structure is presented in detail, alongside with design considerations drawn from the literature and from simulation results. The testing procedure is then described, and experimental results are discussed. The experimental data provided by the integrated sensors correlated with the electro-thermal simulation results indicate the emergence of a failure mechanism and this is later confirmed by failure analysis. Conclusions are further drawn regarding the feasibility of using the proposed integrated sensors for monitoring defects in power ICs.
Core and Wavelength Allocation Schemes for Noise Suppression in Quantum Key Distribution Over Multicore Fiber

In this paper, we propose core and wavelength allocation schemes for the simultaneous transmission of classical signals and quantum key distribution (QKD) over multi-core fiber (MCF), aiming to maximize the secure key rate, and evaluate the proposed schemes in sending-or-not-sending-QKD (SNS-QKD) and Bennett-Brassard-1984-QKD (BB84-QKD). First, we formulate the noise power on quantum channels, and propose a theoretical model of backward cascaded noise of four wave mixing and inter-core crosstalk considering modulation frequency of the classical signals. Also, the impact of noises on secure key rate is calculated in SNS-QKD and BB84-QKD. Then, we propose a core allocation algorithm in order to reduce the noise interference to quantum cores, and the quantum equal frequency spacing (qEFS) and the quantum unequal frequency spacing (qUFS) wavelength allocation schemes are proposed in the same-core (SC) and the different-core (DC) distribution. Finally, we perform numerical simulation and experimental evaluation for the proposed schemes. Compared with the conventional channel allocation (CCA) scheme in SNS-QKD, the proposed schemes can extend the secure transmission distance up to 78.8%. In BB84-QKD, the secure transmission distance can be extended up to 127.1% under SC-qUFS scheme. Experimental results show that the proposed schemes can suppress noise photons up to 57.54% compared to CCA scheme.
The Emerging Clinical Significance of the Red Cell Distribution Width as a Biomarker in Chronic Obstructive Pulmonary Disease: A Systematic Review

There is an intense focus on the identification of novel biomarkers of chronic obstructive pulmonary disease (COPD) to enhance clinical decisions in patients with stable disease and acute exacerbations (AECOPD). Though several local (airway) and circulatory inflammatory biomarkers have been proposed, emerging evidence also suggests a potential role for routine haematological parameters, e.g., the red cell distribution width (RDW). We conducted a systematic literature search in PubMed, Web of Science, and Scopus, from inception to April 2022, for articles investigating the diagnostic and prognostic role of the RDW in stable COPD and AECOPD. The risk of bias was assessed using the Joanna Briggs Institute Critical Appraisal Checklist. Significant associations between the RDW and the presence and severity of disease, outcomes (mortality, hospital readmission), and other relevant clinical parameters (right heart failure, pulmonary arterial hypertension) were reported in 13 out of 16 studies in stable COPD (low risk of bias in 11 studies), and 17 out of 21 studies of AECOPD (low risk of bias in 11 studies). Pending further research, our systematic review suggests that the RDW might be useful, singly or in combination with other parameters, for the diagnosis and risk stratification of patients with stable COPD and AECOPD (PROSPERO registration number: CRD42022348304).
Sociocultural Information Gap in the Dive Tourism Industry: Evidence from Komodo National Park

Through the perspective of partnership for Sustainable Development Goals (SDGs 17th), this study aims to identify and describe the information gaps among stakeholders of the dive tourism industry of Komodo National Park as one of the super-priority tourism destinations in Indonesia. Researchers studied documents, performed field observation, and conducted in-depth interviews with 20 stakeholders. Qualitative content analysis revealed several notable findings. First, the information gaps among stakeholders are generally linked to knowledge disparity about tourism-technical and local sociocultural issues. Sociocultural information, particularly on environment preservation issues, shows the tendency to predominate everyday discourse rather than tourism technical information. Second, the foreigner community appears to be better than local stakeholders at mastering the sociocultural information discourse, particularly in terms of collaboration on environment preservation information. Further studies are needed to examine the interaction among actors predominating the sociocultural information management and their strategies to collaborate in maximizing the role of Destination Management Organization-Destination Governance (DMO-DG).
Model theory with applications to algebra and analysis

Preface List of contributors 1. Conjugacy in groups of finite Morley rank Olivier Frecon and Eric Jaligot 2. Permutation groups of finite Morley rank Alexandre Borovik and Gregory Cherlin 3. A survey of asymptotic classes and measurable structures Richard Elwes and Dugald Macpherson 4. Counting and dimensions Ehud Hrushovski and Frank Wagner 5. A survey on groups definable in o-minimal structures Margarita Otero 6. Decision problems in algebra and analogues of Hilbert's tenth problem Thanases Pheidas and Karim Zahidi 7. Hilbert's tenth problem for function fields of characteristic zero Kirsten Eisentrager 8. First-order characterization of function field invariants over large fields Bjorn Poonen and Florian Pop 9. Nonnegative solvability of linear equations in ordered Abelian groups Philip Scowcroft 10. Model theory for metric structures IItai Ben Yaacov, Alexander Berenstein, C. Ward Henson and Alexander Usvyatsov.
Feasibility of audio-visual teaching materials to support tennis learning

This study aims to produce court tennis audio-visual teaching materials and determine the effectiveness of audio-visual teaching materials to support court tennis learning. This research is development research with stages: needs analysis, data collection, product development, expert validation, product testing, product revision, and evaluation. The subjects of this study were taken using a random sampling method, amounting to 47 people. The instruments used to collect data were questionnaire sheets, expert validation sheets and further tests were analyzed using descriptive statistics. Seeing the effectiveness of the product using an experimental design with the format "one group pretest-posttest design", which does not use a comparison class but has used an initial test so that the magnitude of the effect due to the use of the product can be known with certainty. The results showed that the results of the validation of media experts, learning experts material experts were very valid and the validation of evaluation experts was quite valid. The quality of the product from the large-scale test is categorized as high. The results of the product effectiveness test show a significant and efficient increase in learning outcomes and have a fairly high attractiveness in supporting court tennis learning.
A Study on the Nature of SARS-CoV-2 Using the Shell Disorder Models: Reproducibility, Evolution, Spread, and Attenuation

The basic tenets of the shell disorder model (SDM) as applied to COVID-19 are that the harder outer shell of the virus shell (lower PID—percentage of intrinsic disorder—of the membrane protein M, PIDM) and higher flexibility of the inner shell (higher PID of the nucleocapsid protein N, PIDN) are correlated with the contagiousness and virulence, respectively. M protects the virion from the anti-microbial enzymes in the saliva and mucus. N disorder is associated with the rapid replication of the virus. SDM predictions are supported by two experimental observations. The first observation demonstrated lesser and greater presence of the Omicron particles in the lungs and bronchial tissues, respectively, as there is a greater level of mucus in the bronchi. The other observation revealed that there are lower viral loads in 2017-pangolin-CoV, which is predicted to have similarly low PIDN as Omicron. The abnormally hard M, which is very rarely seen in coronaviruses, arose from the fecal–oral behaviors of pangolins via exposure to buried feces. Pangolins provide an environment for coronavirus (CoV) attenuation, which is seen in Omicron. Phylogenetic study using M shows that COVID-19-related bat-CoVs from Laos and Omicron are clustered in close proximity to pangolin-CoVs, which suggests the recurrence of interspecies transmissions. Hard M may have implications for long COVID-19, with immune systems having difficulty degrading viral proteins/particles.
Ultrasound-Based Hepatic Elastography in Non-Alcoholic Fatty Liver Disease: Focus on Patients with Type 2 Diabetes

Non-alcoholic fatty liver disease (NAFLD) is the most prevalent liver disease and is the hepatic expression of metabolic syndrome. The development of non-invasive methods for the diagnosis of hepatic steatosis and advanced fibrosis in high-risk patients, especially those with type 2 diabetes mellitus, is highly needed to replace the invasive method of liver biopsy. Elastographic methods can bring significant added value to screening and diagnostic procedures for NAFLD in patients with diabetes, thus contributing to improved NAFLD management. Pharmacological development and forthcoming therapeutic measures that address NAFLD should also be based on new, non-invasive, and reliable tools that assess NAFLD in at-risk patients and be able to properly guide treatment in individuals with both diabetes and NAFLD. This is the first review aiming to outline and discuss recent studies on ultrasound-based hepatic elastography, focusing on NAFLD assessment in patients with diabetes.
Deletion of Growth Hormone Secretagogue Receptor in Kisspeptin Neurons in Female Mice Blocks Diet-Induced Obesity

The gut peptide, ghrelin, mediates energy homeostasis and reproduction by acting through its receptor, growth hormone secretagogue receptor (GHSR), expressed in hypothalamic neurons in the arcuate (ARC). We have shown 17β-estradiol (E2) increases Ghsr expression in Kisspeptin/Neurokinin B/Dynorphin (KNDy) neurons, enhancing sensitivity to ghrelin. We hypothesized that E2-induced Ghsr expression augments KNDy sensitivity in a fasting state by elevating ghrelin to disrupt energy expenditure in females. We produced a Kiss1-GHSR knockout to determine the role of GHSR in ARC KNDy neurons. We found that changes in ARC gene expression with estradiol benzoate (EB) treatment were abrogated by the deletion of GHSR and ghrelin abolished these differences. We also observed changes in metabolism and fasting glucose levels. Additionally, knockouts were resistant to body weight gain on a high fat diet (HFD). Behaviorally, we found that knockouts on HFD exhibited reduced anxiety-like behavior. Furthermore, knockouts did not refeed to the same extent as controls after a 24 h fast. Finally, in response to cold stress, knockout females had elevated metabolic parameters compared to controls. These data indicate GHSR in Kiss1 neurons modulate ARC gene expression, metabolism, glucose homeostasis, behavior, and thermoregulation, illustrating a novel mechanism for E2 and ghrelin to control Kiss1 neurons.
A Non-Stationary 3D-GBSM V2V Channel Model for Wideband Massive MIMO Systems

This letter presents a non-stationary 3D-GBSM vehicle to vehicle (V2V) channel model in tunnel environment based on massive multiple-input multiple-output (MIMO) antenna arrays. Instead of plane wavefront assumptions used in traditional MIMO systems, the proposed channel model considers spherical wavefront assumption for V2V communications. Firstly, the channel impulse response (CIR) and closed-form expression for probability density function (PDF) of angle-of-departure (AoD) and angle-of-arrival (AoA) in elevation and azimuth planes are derived. Afterwards, the expressions for the spatial cross-correlation function (S-CCF) and doppler power spectrum density (DPSD) due to the non-stationarity of transmitting (NT) and receiving (MR) antenna arrays are derived by considering different time separation, antenna arrays spacing, moving velocity, and $K$ -factor for line of sight (LoS) and non-line of sight (NLoS) propagation paths. The statistical characteristics of the proposed V2V wideband massive MIMO model are validated by measurement, analytical, and simulation results, verifying the effectiveness and adaptability of the proposed model in high-speed train (HST) environment.