Miracle-dz/UniFAR-FTUs huggingface dataset:
Green Tea as a Supportive Treatment for Respiratory Disorders in Calves

Abstract: 90 Friesian calves belonging to Alexandria governorates, Egypt, included in this study and classified into 3 groups, group A: Consist of 20 apparently clinically healthy calves kept as a control, group B: contains 35 calves shows respiratory manifestation, treated with traditional therapy, group C: includes 35 calves exhibit signs of respiratory affection, treated with the same traditional drugs in addition to green tea extract (GTE). Complete early rapid recovery observed in group C than traditionally treated calves. Significant changes in serum creatinine and activity of AST and ALT were observed in group B and C in comparison with healthy calves. There were a significant decreases in the mean values of total antioxidant capacity, catalase activity, reduced glutathione (GSH), glutathione peroxidase (GSH-Px) activity and super oxide dismutase (SOD) activity in group B in comparing with control animals and group (C), while the same previously mentioned values showed a significant increase in group C in comparing with group A and B. On the other hand there is a significant increase and significant decrease in the activity of lipid peroxidase in group B and C, respectively when comparing with control group and with each other. The investigation revealed a significant decreases in the mean values of sodium and chloride with significant increase in potassium level in group B when compared with both control calves and group (C), while the same previously mentioned elements showed non-significant changes in group C when compared with the other two groups.
Quantifying the Polygenic Architecture of the Human Cerebral Cortex: Extensive Genetic Overlap between Cortical Thickness and Surface Area

Introduction The thickness of the cerebral cortical sheet and its surface area are highly heritable traits thought to have largely distinct polygenic architectures. Despite large-scale efforts, the majority of their genetic determinants remains unknown. Our ability to identify causal genetic variants can be improved by employing better delineated, less noisy brain measures that better map onto the biology we seek to understand. Such measures may have fewer variants but with larger effects, i.e. lower polygenicity and higher discoverability. Methods Using Gaussian mixture modeling, we estimated the number of causal variants shared between mean cortical thickness and total surface area. We further determined the polygenicity and discoverability of regional cortical measures from five often-employed parcellation schemes. We made use of UK Biobank data from 31,312 healthy White European individuals (mean age 55.5, standard deviation (SD) 7.4, 52.1% female). Results Contrary to previous reports, we found large genetic overlap between total surface area and mean thickness, sharing 4427 out of 7150 causal variants. Regional surface area was more discoverable (p=4.1×10−6) and less polygenic (p=.007) than regional thickness measures. We further found that genetically-informed and less granular parcellation schemes had highest discoverability, with no differences in polygenicity. Conclusions These findings may serve as a roadmap for improved future GWAS studies; Knowledge of which measures or parcellations are most discoverable, as well as the genetic overlap between these measures, may be used to boost identification of genetic predictors and thereby gain a better understanding of brain morphology.
An Efficient Method for Mitigating Longevity Value-at-Risk

Many of the existing index-based longevity hedging strategies focus on the reduction in variance. However, solvency capital requirements are typically based on the τ-year-ahead Value-at-Risk, with τ = 1 under Solvency II. Optimizing a longevity hedge using variance minimization is particularly inadequate when the cost of hedging is nonzero and mortality improvements are driven by a skewed and/or heavy-tailed distribution. In this article, we contribute a method to formulate a value hedge that aims to minimize the Value-at-Risk of the hedged position over a horizon of τ years. The proposed method works with all stochastic mortality models that can be formulated in a state-space form, even when a non normal distributional assumption is made. We further develop a technique to expedite the evaluation of a value longevity hedge. By utilizing the generic assumption that the innovations in the stochastic processes for the period and cohort effects are not serially correlated, the proposed technique spares us from the need for nested simulations that are generally required when evaluating a value hedge.
Epidemiology of orthopaedic trauma in Istanbul level 3 private hospital

Background: The distribution of patients who were admitted to the hospital for trauma depends on the location of hospital and the distribution of the population where the hospital is located . The aim was to answer the question regarding the distribution of orthopaedic traumas which were admitted to the emergency service of level 3 a private hospital and to be able to shed light on necessary training and equipment for the aforementioned emergency departments. Methods: The distribution of the patients who were admitted to level 3 private hospital for a year was analyzed retrospectively. The patients who admitted between January 2014 and January 2015 were divided into subgroups as upper extremity, lower extremity, vertebral disk pathology, vertebral trauma, infection and soft tissue trauma, accompanying thoracic trauma and then they were taken into consideration. Results: A total of 1538 patients admitted during a 12-month period. The number of the patients with upper extremity trauma was 539 while that of lower extremity was 423. There were 365 patients with vertebral trauma which was followed by 94 patients with pelvic trauma. The remaining patient group had thoracic trauma. Conclusions: The patients aged between 30-39 years constituted the majority of the cases in present study. The upper extremity injuries were predominant. Also, the number of male patients was higher in every month. The center where the hospital is located plays an important role in determining the age group and type of trauma.
Evaluation of feedback from 2nd professional medical students on various teaching-learning and assessment methods in Pharmacology

Objectives: This study was designed to obtain & evaluate feedback on teaching-learning and assessment methods. Material and Methods: A structured questionnaire was designed and prevalidated. After obtaining permission from Institutional Ethics Committee questionnaire was given to students of 2017 batch who had completed their 5th semester teaching schedule of pharmacology. They were asked to fill the questionnaire honestly without any pressure and give their valuable feedback on various teaching-learning and evaluation methods used in our pharmacology department during their classes and exams. Results: One hundred fifteen students participated in the study. Majority of students (58.3%) are in favor of teaching pharmacology bedside in hospital. Among second year subject pharmacology was favorite of 39.1% students. 68.7% recommended interaction during classes that helps them the most to concentrate during lecture. Greater number of students (74.8%) find combination of chalk and board, PPT and audio video are more effective method to learn pharmacology in lectures having duration of 45mins (53.9%). Written and viva test after completion of each system and their feedback within a week help them most to prepare pharmacology for university examination. Conclusion: This states that the constant updating of teaching methods are required to keep students more focused, interested and to cop up with the newer generation of students. Regular assessment and their timely feedback helps them to find out their weaknesses and strengths which will help them to prepare for their university examinations. Keywords: Evaluation, Teaching-learning, Feedback, Pharmacology.
Analysis Of Brand Experience And Brand Satisfaction With Brand Loyalty Through Brand Trust As A Variable Mediation

This research examines the influence of brand experience and brand satisfaction of brand loyalty with brand trust as intervening variable. The samples used in this study were 130 respondents who were Honda motorcycle customers in Medan city. Nonprobability sampling Technique by purposive sampling method is used as a sampling technique. The analysis method is Structural Equation Modeling (SEM) using the AMOS-20 (Analysis of Moment Structure) device. It was found that brand experience and brand Trust have significant effect on brand trust and brand loyalty. Brand Trust is a significant effect on brand loyalty. Brand Trust is a partial mediation the influence of brand experience and brand trust of brand loyalty.
Tomografía por Emisión de Positrones cuantificada en la evaluación prequirúrgica de la epilepsia

Hipotesis La PET con 18F-FDG cuantificada con programas informaticos es util para localizar la ZE en la valoracion prequirurgica de pacientes con epilepsia refractaria al tratamiento farmacologico. Objetivos Objetivo principal: Valorar la utilidad diagnostica de la PET con 18F-FDG cuantificada con programas informaticos para la deteccion de la ZE en pacientes con epilepsia farmacorresistente. Objetivos secundarios: 1. Optimizar el analisis cuantificado con el programa SPM para la deteccion de la ZE en estudios PET normales o dudosos al analisis visual. 2. Desarrollar y validar un nuevo programa informatico de procesamiento de imagenes PET con analisis parametrico para la correcta identificacion de la ZE. 3. Determinar el valor anadido de la PET cuantificada en la deteccion de la ZE respecto al analisis visual. 4. Valorar la utilidad de la PET cuantificada en la deteccion de la ZE respecto a la RM. Conclusiones 1. La PET con 18F-FDG cuantificada con programas informaticos es de gran utilidad como prueba complementaria para la deteccion de la zona epileptogena en pacientes con epilepsia refractaria al tratamiento farmacologico que son valorados para cirugia. 2. El analisis cuantificado de la PET con et programa SPM mediante el uso de dinteles optimizados permite aumentar la deteccion de la zona epileptogena en estudios PET normales o dudosos al analisis visual. El mejor abordaje metodologico para la segmentacion de los mapas parametricos es la utilizacion de valores de p permisivos y tamanos de cluster restrictivos. 3. Se ha desarrollado y validado un nuevo programa informatico, PET-analysis, que plantea un nuevo metodo de procesamiento de imagenes PET con analisis parametrico. PET-analysis ha demostrado ser una herramienta util para la correcta identificacion de la zona epileptogena, con un procesado dinamico de las imagenes PET que permite el uso de varios dinteles de segmentacion de forma rapida, sencilla y en tiempo real. 4. La PET cuantificada con los programas informaticos SPM y PET-analysis ha demostrado ser un metodo objetivo complementario al analisis visual, de gran utilidad para la deteccion de la zona epileptogena. PET-analysis ha mostrado mejores resultados que SPM en un grupo seleccionado de pacientes con epilepsia farmacorresistente. 5. La PET cuantificada con los programas informaticos SPM y PET-analysis es una prueba de neuroimagen complementaria a la RM y que tiene un gran valor para la deteccion de la zona epileptogena, particularmente en los casos en los que la RM no muestra lesiones o es discordante con las otras pruebas diagnosticas de primera linea.
Deuterium retention in Sn-filled samples exposed to fusion-relevant flux plasmas

Tin (Sn) is an attractive option for a liquid metal wall material for future fusion reactors. Control of tritium inventory is key for the successful operation of these reactors, but little data exists up until now on hydrogen isotope retention in Sn. Free surface Sn targets and Sn-based capillary porous structure targets were exposed to deuterium (D) plasma in nano-PSI and magnum-PSI respectively. The retained D inventory was determined using the methods of thermal desorption spectroscopy and nuclear reaction analysis. The retention dependence is somewhat complex due to the mixed composition of the exposed samples as well as their liquid nature. The D retained in both types of Sn targets was found to increase with increasing D plasma fluence. For free surface liquid Sn targets, both thermal desorption spectroscopy and nuclear reaction analysis measurements showed a negative relationship between D retention and sample temperature. For capillary porous structure Sn targets, D retained in the top layer measured by nuclear reaction analysis decreased with temperature while the total D retained measured by thermal desorption spectroscopy remained approximately constant. By extracting pure Sn pieces from the targets it was found that the amount of D retained in pure Sn was much lower than that in the whole Sn-based targets and was estimated to be about 10−7–10−4 D/Sn. D retained at the Sn-wall interface was found to dominate the total amount of D retained in the whole sample and observed cavities between deposited Sn droplets and the wall are the leading candidates responsible for this. Cavity formation is proposed to be the main retention mechanism for D in liquid Sn targets, although enhanced solubility leading to supersaturation under a D plasma environment is mainly responsible for the observed higher D retention in pure Sn compared with normal solubility under D gas. When compared with tungsten, D in Sn samples is of the same order of magnitude at temperatures below 300 °C, but at higher temperatures at least one to two orders of magnitude higher, most likely due to D trapped in cavities.
Assessment of Post Dural Puncture Headache in Patients Undergoing Caesarean Section: A Comparison between 25 G Quinke V/S Whitacre Needles

Background: PDPH (post dural puncture headache) is a common complication Methodology: In this randomised prospective single blind study, 200 patients undergoing Elective Caesarian Section were divided into two groups Q & W (n=100), each to receive subarachnoid block with Quinke needle (25G) and Whitcre Needle (25G) respectively. Assessment of the incidence of postdural puncture headache was done on the 1 st , 2 nd & 3 rd and 5 th postoperative days using a standard questionnaire. The presence, severity duration and nature and onset of headache was assessed. Results: The demographic profile was similar in both groups Q & W. The incidence of post dural puncture headache (PDPH) was greater with 25 G Quinke’s needle. The intensity and duration of PDPH was higher in group Q ie in whom Quinkes needle was used. Nausea and vomiting was also greater in group Q. Conclusion: There was a statistically significant decrease in the incidence of postdural puncture headache using conical tipped pencil point 25G Whitacre spinal needle. There was no statistical difference in the onset of PDPH and the accompanying symptoms with the use of Quinke or Whitacre needles.
Assessment and comparison of urinary protein: creatinine ratios of healthy domestic dogs and working dogs in kennels division in Sri Lanka police for early detection of renal disease

Healthy dogs usually excrete small amounts of protein in urine. Persistently high proteinuria is usually a marker of kidney disease. The urinary protein: creatinine ratio (UPC) is used in quantifying urine protein excretio ney diseases, guiding recommendations for monitoring and treatment of kidney diseases and evaluation of prognosis. However, use of UPC ratio has not been well established/ used to diagnose renal diseases in dogs in Sri Lanka. Therefore, for the first time in Sri Lanka, we used this method to detect UPC ratio of healthy dogs (n=51). Once we established the UPC ratios of healthy dogs, UPC ratios were measured in working dogs (n=45) in Kennels Division of Sri Lanka Police, since renal diseases are a common cause of mortality in these dogs. In control group, the mean UPC ratio was 0.06±0.05. This was similar to the UPC ratio of tracking group among working dogs. Two out of 22 dogs used for explosive duties had UPC ratio within the borderline proteinuric stage (0.2-0.5) according to the staging system implemented by the International Renal Interest Society (IRIS). In the narcotic group 2 out of 12 dogs were borderline proteinuric and one dog was proteinuric. In this study, we have successfully established the measurement of UPC ratio to detect proteinuria in Sri Lankan dogs and have identified dogs that are susceptible to renal diseases.
Influence of normobaric hypoxic exercise on endothelial progenitor cell senescence by in vitro cultivation with conditioned media

Objective Circulating endothelial progenitor cells (EPCs) were shown to be affected in cardiovascular and metabolic diseases. As interventional strategies, hypoxia and exercise are both known to increase the number and enhance the function of EPCs, potentially by extending their lifespan induced by a reduced senescence. Therefore, this pilot study investigated the effect of exercise under normobaric hypoxia on the senescence of EPCs by in vitro cultivation with autologous human serum (AHS). Methods Four healthy trained young males (23 ± 2 years) performed an incremental cycling step test until exhaustion in a normobaric hypoxic-chamber with an average altitude of 4,000 m (O2 12.3%). Blood serum was taken at pre, 10 min post and 4 h post, which was later used for in vitro cultivation of EPCs. Senescence was investigated by ß-galactosidase staining. Results The participants spent 30-40 min in normobaric hypoxia. The EPC senescence rate was reduced 10 min (0.72 ± 0.57%) and 4 hours (0.67 ± 0.52%) after exercise compared to pre (1.89 ± 0.37%). Conclusion This pilot study indicates that intense exercise under normobaric hypoxia may enhance EPC function by slowing down their senescence.
Comparing Public Attitudes towards Science across Provinces in China 1

To illustrate the feature and structure of cultural authority of science in a Chinese context, this study reports on the features and current status of the cultural authority of science across China via a structural analysis of public perceptions of science as measured by cognitive, evaluative and behavioural indicators. Regional socio-economic disparity in China is significant, and we expect that disparity to give rise to diverse public attitudes to science. This study aims not only to enrich the regional data on current international efforts to compare public attitudes to science, but also to provide evidence-based research for other countries to discuss the diversity in the patterns of the cultural authority of science.
Developing Online Sense of Community: Graduate Students’ Experiences and Perceptions

Building a sense of community (SoC) is an important process in the success of distance education and students’ retention. However, developing a community in online learning environments is not an easy task. The purpose of this research study is to explore perceptions of graduate students on SoC and learning after using different collaborative activities with diverse forms of interaction (text, audio, and video) in an online educational research course. Quantitative data from two surveys and qualitative data from individual interviews were collected. Findings indicate that multimodal and scaffolding interactive activities help to support connectedness and learning, and therefore foster online graduate students’ sense of community. The results of this study add to the literature with regard to instructional strategies used to support the development of online sense of community.
Did the Foreign Exchange Market Cheer or Jeer in Response to Political Events? An Event Study of Malaysia – Some Stylised Facts

This paper explores the effects of political events on foreign exchange returns in Malaysia. We identify five recent events that induce political uncertainty on investors, namely the 13th General Election (GE13), the imprisonment of a key opposition politician, the scandal from the 1MDB expose, the appointment of a new Central Bank Governor and the 14th General Election (GE14). Using an event study, our findings show that the imprisonment of the opposition party leader triggered a favourable response from the foreign exchange market. However, market reactions to the 1MDB scandal were followed largely unfavourable. The GE13 triggered unfavourable market response, while the reverse is true for market reactions to GE14. Market response to the appointment of the new Central Bank Governor was rather favourable. The Event Study is the first of its kind that examines the foreign exchange market implications of key political events in Malaysia. There are practical considerations emanating from these findings.
Making a case for 3D printing for housing delivery in South Africa

Considering the need for standard and cost-effective housing delivery in South Africa, this study aims to make a case for three-dimensional (3D) printing in housing delivery through an assessment of the inherent benefits and the factors that could acts as barriers to its adoption. ,The study used a survey of construction professionals currently actively involved in a construction project in the country. Analysis of data gathered was done using a four-step analysis approach and relevant descriptive and inferential statistics were adopted. ,The study revealed through factor analysis that 3D printing in housing delivery promises better cost delivery, increased productivity and stakeholder satisfaction, socio-economic benefits, improved quality and faster housing delivery. While these benefits exist, factors such as technical and operational issues of the 3D printing itself, organizational and personnel issues as well as lack of awareness of the inherent benefits and understanding of the technology among stakeholders can prove to be barriers to the adoption of the technology. ,In the quest to achieve standard and affordable housing which is part of its National Development Plan 2030, the government can adopt 3D printing which promises significant benefits in terms of cost, time, quality, productivity and stakeholders’ satisfaction. Property developers can also adopt the technology to improve their housing delivery, competitive advantage and the economic value of their properties. ,The study contributes significantly to the body of knowledge as it reveals the benefits and barriers of adopting 3D printing in housing delivery in South Africa – an aspect that has not gained significant attention in the fourth industrial revolution and housing delivery discuss in the country.
Siri, Do I like You? Digital Voice Assistants and Their Acceptance by Consumers

Nowadays, digital voice assistants (DVAs) such as Amazon’s Alexa, Google’s Assistant, or Apple’s Siri provide speech-oriented human-computer interfaces that have the potential to make consumers’ interaction with other consumers, firms, or devices more convenient, enjoyable, and productive. However, at least currently, DVA acceptance is limited, even among digital natives and corresponding explanations are missing. This paper seeks to close this gap by investigating which factors have an impact on DVA acceptance. Therefore, we develop a new approach that combines elements of the Technology Acceptance Model (TAM) as well as the Uses and Gratifications Approach (UGA). A sample of 283 digital natives participated in a Siri field experiment. The results demonstrate that especially enjoyment, but also social status and social influence are main DVA acceptance drivers. Nevertheless, Millennials have some privacy concerns about companies getting too much personal information while using DVAs. This study provides valuable insights into main drivers of DVA acceptance. Theoretical and practical implications are discussed.