Miracle-dz/UniFAR-FTUs huggingface dataset:
Intercalating in Medical Education; is it more valuable than other Intercalated Degrees?

Aim: This study aimed to identify whether an intercalated BSc (iBSc) in Medical Education offers long-term career benefits beyond that of traditional iBScs by exploring candidates’ retrospective perceptions. Method: A small-scale study was conducted with doctors who had completed an iBSc at Barts and the London SMD. A mixed methods approach was adopted using a questionnaire (21), and semi-structured interviews (4) to further explore respondent’s perceptions. Results: All iBScs highlight similar curriculum outcomes in terms of research skill development and offer additional points at foundationand specialty training applications. Medical Education respondents reported additional parallel benefits such as teaching alongside research activity, with a greater numbers of outputs e.g. presentations, publications. Understanding educational theory, developing teaching skills and portfolio creation were identified by the Medical Education group as particularly valuable to career progression. Additionally, Medical Educational iBSc candidates felt the course would offer ubiquitous value in the core medical curriculum, with those completing traditional ‘lab based’ iBScs feeling that no aspect of their intercalation had such generic value, and should remain a separate, optional educational intervention. Conclusion: Considering the increasing emphasis on education and teaching in medicine, this study suggests Medical Education offers greater benefit to candidates in the long-term. It follows that incorporation of this in the core medical curriculum would offer value to all candidates.
New Approach to the Concept-Based Teaching and Learning Mathematics at Primary School Level in Papua New Guinea: Concrete-Representational-Abstract (CRA) Sequence of Instruction Guided through Structured Japanese Lesson Pattern

Papua New Guinea (PNG) abolished Outcome Based Education (OBE) curriculum as same as the other countries including South Africa (SA). PNG is now under the transition to Standard Based Education (SBE) as a new educational approach. Its primary intention is to improve the performance of students with standards of important subject like mathematics. In this context, it would be crucial to seek eff ective and applicable methods for teaching and learning of mathematics primarily focusing on the conceptual understanding articulated well with practical skills at the primary school level. Thus, we investigate the applicability of Concrete-Representational-Abstract (CRA) sequence of instruction guided through Japanese lesson pattern to the teaching and learning of the comparison of fraction size. CRA sequence of instruction provides research-based practical framework for lesson design and has been proven to improve the students’ conceptual understanding of mathematics. The Japanese lesson pattern as a structured ‘problem solving’ approach has been identifi ed as one of eff ective practical framework for mathematics lesson delivery in the Trends in International Mathematics and Science Study (TIMSS) video tape study. In this paper, fi rstly we indicate quantitatively and qualitatively that our proposed approach, CRA sequence of instruction guided through structured problem-solving Japanese lesson pattern, has appreciable impact to raise the conceptual understanding of fraction in mathematics education at the primary school level in PNG. The implication of our study is also discussed for the improvement of mathematics education in the educational context of PNG.
Prevalence of diabetic retinopathy and related factors in patients with type 2 diabetes mellitus in Hyderabad and adjoining areas

Diabetic Retinopathy (DR) is the major cause of acquired blindness and visual impairment among the people of working age as well as those aged 60 years or more. The present study was carried out to ensure the prevalence and to examine the factors involved in the progression of DR in T2DM patients from Hyderabad and adjoin areas. Therefore, total 180 patients were observed in our study with type 2 DM out of which 127 were male (70.56%) and 53 were female (29.44%) with different age ranges between 50 to 70 years. The results declared that out of 180, 14 (08%) patients were suffering from mild NPDR,17 patients (09%) from moderate NPDR, 22 subjects (12%) with severe NPDR, 50 patients (28%) from PDR,31 cases (17%) with vitreous hemorrhage and 46 patients (26%) with macular oedema with risk factors in DR patients Hypertension 69.44% Cardiovascular disorder 34.44% HBA1c values mean &(SD) 10.025(2.34), Triglycerides values reported with mean & SD 317.15 (61.48) and Diabetic Duration mean & (SD) 15.54 (24.54).
Osteomalacia or osteoporosis: Case report

The aim of the paper was to show the diagnostic and therapeutic approaches to a patient suffering from osteomalacia, as well as differential diagnosis with osteoporosis. Osteomalacia (OM) is a metabolic disease of bones which appears as a result of defective mineralization of newly formed bone matrix in adults. Diagnosis of disease may represent a big problem. A 67-year-old female patient from Pirot was examined in an outpatient unit by a rheumatologist in the Niska Banja Institute in December 2012. The patient reported pain along the vertebral column and inability to get out of bed. Radiography showed vertebral compression fractures and the patient had previously received surgical care at Orthopedics Ward of General Hospital Pirot due to the left femur fracture. Orthopedist, neurologist, physiatrist and practicing rheumatologist suspected osteoporosis. The diagnosis of osteomalacia was established in February, 2013. The treatment was initiated by introducing large doses of vitamin D and advising bisphosphonates. After eighth months, the patient's general condition was improved. This was demonstrated by her independent mobility.
Chronic Suppurative Otitis Media (CSOM): Evaluation of fungal and aerobic bacterial agents and antibiotic sensitivity pattern of the bacterial isolates

Introduction: Chronic suppurative otitis media (CSOM) is an important cause of preventable hearing loss, particularly in the developing world. Aim: To determine the microbiological profile of CSOM and determine the antibiotic susceptibility testing of aerobic bacteria which will be beneficial for appropr iate treatment there by reducing complications. Methods and Materials: A total of 109 patients with CSOM attending outpatient and admitted inpatient in ENT department were included in the study. Two pus swabs each for infected ear were collected. Specimens were subjected to Gram stain and plated on to appropriate culture media to isolate bacterial and fungal pathogens. Bacterial and Fungal species identification and Antibiotic susceptibility testing of aerobic bacteria of isolated pathogens was done. Results: Out of 109 samples cultured there were 70 bacterial and 14 fungal isolates. Most common aerobic bacterial isolate was Pseudomonas aeruginosa (34.2%) followed by Proteus mirabilis (22.8%) and Staphylococcus aureus (17%). Among fungal isolate, Aspergillus niger (64.3%) was predominant followed by Aspergillus flavus (21.4%) and Candida species (14.3%). Amikacin (91.6%) and Ciprofloxacin(87.5%) showed maximum activity to Pseudomonas aeruginosa. The antibacterial susceptibility pattern of Staphylococcus aureus revealed 58.3% Methcillin resistant Staphylococcus aureus (MRSA) strains. Conclusions: Emergence of Pseudomonas aeruginosa as most common aerobic isolate and high incidence of Methicillin Resistant Staphylococcus aureus in present study indicates the necessity of continuous evaluation of bacteriological profile and antimicrobial susceptibility testing in all CSOM cases. Keywords: Chronic suppurative otitis media (CSOM), Methcillin resistant Staphylococcus aureus (MRSA).
Reforming Undergraduate Statistics Education in the Arab World in the Era of Information

Abstract This article is the first to thoroughly investigate the state of undergraduate statistics education in the Arab world. It discusses evidence with respect to the quality of education in general and statistics education in particular. Based on a survey of statistics programs in Arab universities, several issues pertaining to curriculum structure, pedagogical practices, and matching learning outcomes with labor market needs are discussed. The survey results reveal a gap between the undergraduate statistics programs in Arab universities and the international curriculum guidelines. This gap signals the urgent need for reforming and enhancing statistics education to address the needs of the labor market in this era of information. Recommendations and strategic reforms based on best international practices are outlined.
Equatorial Plasma Bubble Zonal Drift Velocity Variations in Response to Season, Local Time, and Solar Activity across Southeast Asia

This work investigated the zonal drift velocity, VE, of equatorial plasma bubbles (EPBs) which was calculated from the zonal keogram of the rate of total electron content index obtained using the Global Positioning System data from the Malaysia Real‐Time Kinematics GNSS Network over Southeast Asia across the period 2008 until 2013 (498 nights). In general, a long‐term study on the VE of EPBs and its dependence on the season, local time, and solar activity over Southeast Asia by using Global Positioning System multipoint receivers has never been conducted before. The case study showed that the VE estimated from Malaysia Real‐Time Kinematics GNSS Network was basically within a similar range to that of the 630‐nm airglow images obtained at Kototabang, Indonesia. Furthermore, the VE of EPBs was higher during high solar‐activity period, which was in line with past studies. The time range of the EPB VE peak is more accurately determined compared to previous studies. In high solar activity conditions, a peak of VE was observed at 2130 LT (equinox), 2200 LT (June solstice), and after 2300 LT (December solstice). After this peak, the EPB VE steadily decreased with time during the equinox and was varied throughout the night during June solstice. Moreover, it was found to differ with time from the evening to the postmidnight period during December solstice.
The importance of a research case definition

ABSTRACT All scientific activities with diseases rely on the selection of reliable and valid case definitions in order to accurately estimate prevalence rates, to identify biological markers, and to understand the outcomes of treatment trials. The failure to develop a consensus on which research case definition to use for defining Myalgic Encephalomyelitis (ME) and chronic fatigue syndrome (CFS) has had negative consequences for the scientific and patient community. If case definition criteria inappropriately select patients with symptoms due to primary affective disorders, other fatiguing medical conditions, burnout, or over-committed lifestyle issues, the scientific consequences are serious. For example, a case definition that is too broad would include individuals with other illnesses and conditions, complicating the tasks of estimating prevalence rates or identifying effective treatment programs. A consensus on a research case definition and its operationalization and assessment would enable investigators to select more homogenous samples that could expedite the identification of valid biological markers, and consequently reduce misperceptions regarding the role of psychogenic versus biomedical factors. Our editorial reviews the implications of previous research and clinical case definitions in CFS and ME domains.
Assessment Methods in Vitiligo

Copyright: © 2015 Dicle O. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Natural course of vitiligo include flares, remissions and spontaneous repigmentation. Knowledge of the initial extent and severity of vitiligo is essential for making prognoses and therapeutic choices and is also fundamental to the evaluation of treatment efficacy. In a systematic review on randomized controlled trials of interventions for vitiligo, over a period of forty three years, numerous outcome measures were identified. Of the fifty-seven included studies, none of the studies used exactly the same method of scoring [1]. In another systematic summary of fifty-four randomized controlled trials on vitiligo treatment outcomes it was found out that at least twenty-five different outcome measures were used [2]. The majority of these trials defined the primary outcome as repigmentation and even repigmentation was measured by forty-eight different scales in these trials [2].
Non-Catalytic Oxidative Desulfurization of Diesel Oil Using Ozone in a Biphasic Oil/Acetonitrile System

Wei Zhang1,3, Guoying Xie1,2, Yujie Gong1, Dongxu Zhou1, Chen Zhang1,3 and Qiaona Ji2 1 School of Chemical Engineering, Beijing Institute of Petrochemical Technology, Beijing 102617, P. R. China 2 College of Biological and Pharmaceutical Engineering, Wuhan Huaxia University of Technology, Wuhan 430223, P. R. China 3 Beijing Key Laboratory of Fuels Cleaning and Advanced Catalytic Emission Reduction Technology, Beijing 102617, P. R. China
Reduction of IL‐6 gene expression in human adipose tissue after sleeve gastrectomy surgery

There is increasing evidence that immune cell interactions in adipose tissue contribute to the development of metabolic dysfunction. Pro‐inflammatory cytokines have been shown to mediate insulin resistance, and the presence of macrophages is a salient feature in the development of obesity. The present study aimed to evaluate adipocyte size and macrophage activation in women before and 3 months after laparoscopic vertical sleeve gastrectomy (VSG).
Clinical characteristics of ALK+ NSCLC patients (pts) treated with crizotinib beyond disease progression (PD): Potential implications for management.

7600 Background: Crizotinib is a first-in-class oral ALK inhibitor for the treatment (tx) of advanced ALK-positive (ALK+) NSCLC. Dramatic and prolonged responses to crizotinib are common, but pts do experience PD. Methods: Clinical characteristics of ALK+ NSCLC pts enrolled onto two multicenter, single arm trials of crizotinib (A8081001, PROFILE 1005) with investigator-defined PD who were allowed to continue crizotinib if, in the investigator’s opinion, there was reasonable evidence of ongoing clinical benefit were assessed. A period of ≥2 wks was chosen as a reasonable minimum duration of post-PD crizotinib tx. Results: As of 1 June 2011, 146 pts (A8081001, n=61, PROFILE 1005, n=85) had PD. PD was observed in new lesions only (1 organ site, n=62; >1 organ site, n=18), target ± new lesions (≥ 1 organ site, n=55), clinical PD (n=9), and no site assessment (n=2). Most common new lesions in single organ sites were brain (brain MRI not mandatory; n=25), liver (n=20), bone (n=4), and kidney (n=1). Of the 146 p.
Using the intervention mapping protocol to promote school-based physical activity among children: A demonstration of the step-by-step process

Objective: This study describes the step-by-step development of the IMove30+ programme and outlines lessons derived from the authors’ experience using an intervention mapping protocol (IMP)-based programme design. The programme was designed to increase the moderate to vigorous physical activity (PA) level at school among Lebanese children, aged 10–12 years. Design: Participatory cross-sectional design including group and individual interviews. Setting: Sidon district of Lebanon. Method: The programme was co-designed with a planning committee and included a local leader in school health, school staff including nurses and members of the target population (schoolchildren). The programme was developed using the six steps of the IMP: elaborating a logic model of the problem, formulating programme objectives, choosing the theoretical methods (i.e. the theory-based techniques used to influence a change objective) and practical applications (i.e. the applied strategies based on those theoretical methods), designing the programme, planning programme implementation, and planning the evaluation. Participants’ involvement in the programme’s activities was entirely voluntary. Results: Implemented by teachers and school nurses, this 14-week school-based programme was designed to provide an additional 30 minutes of school-based PA per day through structural environmental change, educational activities, a PA-monitoring system and PA events at school and in the classroom as well as during recess. Conclusion: IMP enabled the rigorous and systematic development of the programme to improve children’s PA level. The programme description and the lessons learned can facilitate the replication and the scaling up of the programme in other settings.
Investigating the role of Intellectual Capital on the performance of pharmaceutical firms in Thailand

This is acknowledged that intellectual capital is a vital success element in a progressively competitive and universal economy. Intellectual capital is a combination of three type of capital i.e â€œhuman capital, structural capital and relational capitalâ€. These three capital creates value for the firm and play important role to boost the performance of any firm. This study intended to examine the relationship between intellectual capital and firm performance of pharmaceutical firm in Thailand. For the investigation of proposed associations among the variables, quantitative research approach with cross sectional method was carried out and data was collected by using survey questionnaires. This study found that three types of intellectual capital have significant and positive influence on the performance of Thai pharmaceutical firm. Findings of the study highlights provide guidelines to business owners and managers regarding the management of intellectual capital effectively. Moreover, findings of this research will be helpful in formulation of policies to achieve better performance.
Clinical outcomes after lung transplantation for fibrosis in telomerase related genes mutation carriers

Carriers of telomerase related genes (TRG) mutation seem to present a worst prognosis with more common hematological complications after lung transplantation (LT) for pulmonary fibrosis. The aim of this study was to describe the outcomes after LT and identify pre-LT prognosis factors in a multicenter cohort of lung transplant recipients with TRG mutation. We retrospectively reviewed all identified patients with pathogenic TRG mutation (n=38; TERT, n=22, TERC, n=10, RTEL1, n=6) who received LT in France, Switzerland and Belgium between 2009 and 2018. The median age at LT was 54 years (46-59), 70% were male, and 60% had idiopathic pulmonary fibrosis (IPF). At diagnosis of pulmonary fibrosis, 84% had a hematological disease, including 8 with myelodysplasia, and 45% had a liver disease. After a median follow up of 2.2 years (1,2-3,7), 16 received a single LT, 22 a double LT and 2 a combined liver-LT. The overall post-LT median survival was 3.75 years (1.8-NA). Patients with myelodysplasia before LT had an increased risk of death after LT (HR= 4.12 (1.47-11.53) p=0.007). After LT, all patients showed anemia, 70% thrombocytopenia, and 60% neutropenia. Four patients showed severe liver disease: portal hypertension, cirrhosis. Sixteen patients (42%) experienced acute renal failure and 18 (47%) developed chronic renal insufficiency during follow up. Four developed chronic lung allograft dysfunction. Overall survival after LT supports LT in TRG mutation carriers. Careful evaluation at diagnosis, might limit LT indication for patients with established myelodysplasia.
ANALYSIS OF DONOR CORNEA RETRIEVAL DATA- HOSPITAL AND RESIDENCES

BACKGROUND The voluntary eye donation is still the most popular methods of eye donation in our country. Since last three decades, the voluntary eye donation is promoted by a number of NGOs and Government of India. The meaning of voluntary eye donation is that an individual has prior knowledge about eye donation and also has the contact number of the eye bank. When they come across any death in their community, they will contact the eye bank for eye donation. As per Eye Bank Association of India, the incidence of total blindness is 8.9 million and 1% of this is corneal blindness. Each year, 25,000 to 30,000/new corneal blind patients are added. The voluntary eye donation is not sufficient in providing transplantable corneas to the corneal blind. As our concentration is mainly on voluntary eye collections, this is one of the main reasons that we are unable reach our target of sight restoration in the management of corneal blindness. In this study, we have analysed the voluntary eye donations procured from residence and hospital. The aim of the study is to compare corneas procured by hospital eye donations and residence eye donations to look into all factors that contribute to a transplantable cornea.
Environmental Sanitation and Hygiene on Waste Collector in TPA Piyungan Bantul Yogyakarta

A garbagemen involved directly with garbage, it causes a garbagemen have injuried oftenly when they do their duty. Based on center of worker trans department Jakarta, the injury case causes has 81.169. A garbagemen risk, highly to influence. This is a descriptive kualitative research, the subject are garbagemen who lived in TPA Piyungan and people who involved to manage TPA Piyungan, Bantul Yogyakarta. Research use observed method and In-Depth Interview method. Data analyzed as kualitative descriptive. Data collected by triangulasi source technique.The result that sanitation and hygienic environtment and how to keep the environtment clean, and to maintain the risk environment work on the garbageman area is deficient. The suitability between sanitation and hygiene environment on the garbagemen still need to improve. Financing is the problem of the garbagemen, hygiene environment on garbagemen work area’s very deficient, that things happened too for willingness and act to create a healthy environment.
Classification and Evaluation of Concepts for Improving the Performance of Applied Energy System Optimization Models

Energy system optimization models used for capacity expansion and dispatch planning are established tools for decision-making support in both energy industry and energy politics. The ever-increasing complexity of the systems under consideration leads to an increase in mathematical problem size of the models. This implies limitations of today’s common solution approaches especially with regard to required computing times. To tackle this challenge many model-based speed-up approaches exist which, however, are typically only demonstrated on small generic test cases. In addition, in applied energy systems analysis the effects of such approaches are often not well understood. The novelty of this study is the systematic evaluation of several model reduction and heuristic decomposition techniques for a large applied energy system model using real data and particularly focusing on reachable speed-up. The applied model is typically used for examining German energy scenarios and allows expansion of storage and electricity transmission capacities. We find that initial computing times of more than two days can be reduced up to a factor of ten while having acceptable loss of accuracy. Moreover, we explain what we mean by “effectiveness of model reduction” which limits the possible speed-up with shared memory computers used in this study.