Miracle-dz/UniFAR-FTUs huggingface dataset:
The care of kin : a case study approach to kinship care in the south of England and Zululand, South Africa

This thesis focuses on kinship care specifically for children and young people requiring this provision away from their biological parent and for whom Children’s Social Services, United Kingdom and Child Welfare Agencies, South Africa, have a statutory responsibility (UK CA, 1989; SA CA, 2005). The study explores kinship care from a multifaceted viewpoint. A case study approach, incorporating interviews and observations was adopted for the data collection and a thematic analysis approach utilised for the data analysis. A total of thirty-two interviews were undertaken, in both the United Kingdom and South Africa, involving seventeen kinship carers and fifteen social workers. This study highlights practice complexities experienced in the care of kin in the United Kingdom and South Africa and considers similarities and differences across the two distinct cultural settings and relevant philosophical, but divergent, underlying ideologies. Findings from this study show that kinship carers who participate in statutory assessments are forced to surrender some of their privacy and autonomy in return for legal endorsement and financial remuneration. Attitudes towards kinship carers are dependent on the social construction of an underlying cultural philosophy or ideology that determines what is best for the child in each country. Specifically, in relation to the United Kingdom, the study found that kinship legislation is often ignored by local authorities, and tacitly ignored by other government agencies. With regard to South Africa, the study found that the poverty issues in Zululand prevent carers from adequately caring for their kin, and issues of illiteracy prevent many carers applying for grants that would alleviate their situations. This research clearly demonstrates that immediate changes need to be made to improve the way in which kinship care legislation and policy are created and then put into practice in both countries. Furthermore, recommendations are made in relation to the training and up-skilling of social workers involved in kinship care provision.
Designing Learning Spaces for Effective Learning

The connections between the design and use of space in higher education, and the production of teaching and learning, and of research, are not well understood. This study reports the developmental steps prior building the learning spaces in Universiti Sains Islam Malaysia (USIM). Space issues in higher education have usually been considered either in the context of space planning (the aim of which is to provide appropriate amounts of space for defined uses, and to maximise its use once provided) or as part of campus planning and building design. The findings report the level of design effectiveness of the learning spaces in USIM. The recommendation from learning space users to be utilised on the design improvement for the next learning spaces in USIM will be reported in this study
Enhanced testing can substantially improve defence against several types of respiratory virus pandemic

Mass testing to identify and isolate infected individuals is a promising approach for reducing harm from the next acute respiratory virus pandemic, potentially avoiding the need for indiscriminate social distancing measures whilst averting hospitalizations and deaths. To understand scenarios where mass testing might or might not be a viable intervention, here we modelled how effectiveness depends both on characteristics of the pathogen (R0, time to peak viral load) and on the testing strategy (limit of detection, testing frequency, test turnaround time, adherence). We base time-dependent test sensitivity and time-dependent infectiousness on an underlying viral load trajectory model. We show that given moderately high public adherence, achievable frequent testing can prevent as many transmissions as more costly interventions such as school or business closures. With very high adherence and fast, frequent, and more sensitive testing, we show that most respiratory virus pandemics could be controlled with mass testing alone.
A scoping review of online food retail: Who is using it, what they are buying, and what tactics are used to promote healthy or unhealthy purchases

Online grocery shopping is an increasingly common part of the retail food environment. However, existing reviews have yet to synthesize the large swath of online grocery shopping research. We searched seven databases for studies reporting empirical data on online grocery retailing and shopping. Two reviewers screened search results and extracted information from 117 manuscripts containing 122 studies. Most studies were conducted in North America, Europe, and Asia. Younger, highly educated, and higher-income individuals were most likely to use online grocery and time savings, convenience, and website usability were the most common motivators for use. Common deterrents included the inability to pick perishable items and a lack of trust in the in-store shopper. Barriers included delivery and service fees, difficulty navigating online ordering, and limited availability. Individuals were more likely to purchase bulky/heavy items and less likely to purchase impulse items and perishables like fresh produce. The most common online retail promotion was price discounting. However, shoppers reported that marketing tactics seemed less noticeable online compared to brick-and-mortar stores. Online grocery has gained popularity; nevertheless, barriers may reflect inequities in access. Research is needed to further understand how shopping online influences overall food purchases and how to ensure equitable access.
What Influences farm size growth? An Illustration in Southwestern France

Farm size in industrialized countries grew significantly over the second half of the twentieth century. Using several econometric models, this article examines factors that influence farm size, the probability of an increase in farm size, and the intensity of farm growth. We find that farm structural characteristics, farmer's age, the existence of a successor, and spatial factors approximating urban influences have a significant impact on farm size, whereas human capital variables do not. This study considers a representative sample of 5,000 professional farms in the Midi-Pyrenees region between 2000 and 2007.
Cytokines (IL1β, IL6, TNFα) and serum cortisol levels may not constitute reliable biomarkers to identify individuals with post-acute sequelae of COVID-19

Background: Post-acute sequelae of COVID-19 (PASC) comprise a broad spectrum of symptoms such as fatigue, general weakness, compromised attention and sleep or anxiety disorders. PASC represents a medical and socio-economic challenge. Objectives: Our study evaluated cytokines (IL-1β, IL-6 and TNFα) and cortisol levels in a cohort of typical patients with PASC, suffering concentration problems, fatigue and difficulties finding words. Design: This was a prospective cohort study. Four groups were analysed and compared: those who had never contracted SARS-CoV-2 (n = 13), infected but had no PASC (n = 34), infected with former PASC that resolved (n = 40) and patients with ongoing PASC after infection (n = 91). Methods: Cytokine and cortisol serum levels were determined in patients’ blood samples. Results: Cytokine levels of IL-1β, IL-6, TNFα and cortisol levels did not differ between groups analysed. Conclusion: This may indicate a non-organic/psychosomatic genesis of PASC; further studies are needed to elucidate the underlying causes of PACS, and non-organic causes should not be overlooked.
Physical activity status and its association with quality of life among children with down syndrome in Saudi Arabia: A comparative cross-sectional study

Background Down syndrome is a genetic disorder that causes physical and cognitive challenges. Identifying the impact of sedentary behavior and physical activity on people with Down syndrome is crucial for early intervention. The purpose of this study is to compare physical activity and sedentary behavior among children with Down syndrome and typically developing children, as well as assess their relationship with quality of life. Methods In the cross-sectional study, 67 children between the ages of 6 and 12 were enrolled: 29 in the Down syndrome group and 38 in the typically developing group. Each child wore an ActiGraph wGT3X-BT for seven days. Accelerometer data and quality of life data were analysed. Results Physical activity and sedentary behavior were not significantly different between the Down syndrome and typically developing groups (p ˃ .05). With large effect sizes (partial eta squares ranging from 0.21 to 0.59), typically developing children had a significantly better quality of life than children with Down syndrome. There was a weak positive correlation between moderate physical activity and school performance in children with Down syndrome. For typically developing children, there is a weak negative correlation between light physical activity and physical function, school function, and total paediatric quality of life scale scores. Conclusions This study indicates that children with Down syndrome have participated in more physical activities, resulting in a reduction in differences between them and typically developing children. Additionally, typically developing had higher quality of life than children with Down syndrome. For healthcare professionals and educators, these findings provide valuable insights into developing strategies to enhance physical activity for children with developmental disabilities.
Just Not Enough: Utilization of Outpatient Psychotherapy Provided by Clinical Psychologists for Patients With Psychosis and Bipolar Disorder in Switzerland

Treatment guidelines state that evidence-based psychotherapy is effective for people with psychosis and bipolar disorder and should be offered during every phase of the treatment process. However, research has indicated a lack of outpatient psychotherapeutic services for this patient group, for example, in the United States or Germany. We extend this finding by presenting survey data from Switzerland. We surveyed 112 inpatients with a diagnosis of a schizophrenia spectrum disorder or bipolar disorder and assessed outpatient treatment over the 5 years prior to their index hospitalization by using retrospective self-reports. The survey focused on psychotherapy provided by clinical psychologists. Results indicate that only 23.2% of participants retrospectively reported having utilized any outpatient psychotherapy within the reporting period and only 8% of participants reported having received a number of outpatient sessions that reaches recommended levels of psychotherapy. Exploratory analyses did not detect a significant association between self-reported utilization of outpatient psychotherapy sessions and most demographic, psychiatric, and psychological attributes, but patients with a bipolar disorder diagnosis (vs schizophrenia spectrum diagnosis) reported having utilized outpatient treatment more often. These findings are preliminary. When replicated they highlight the need for increased access to outpatient psychotherapy and better alignment between guideline recommendations and outpatient supply.
Preliminary observations on the effects of artificial light on the marine environment, with special reference to three fish species of commercial value protected by Miramare Marine Reserve

Aims of this study are to give a contribution to the knowledge on the widespread use of light fishing in the Gulf of Trieste, and to obtain a preliminary evaluation of the effects of light fishing on a marine protected area, to improve the quality of marine resource management. The work consists of two main sections: the first one consists of several measurements of underwater light attenuation data collected in the marine environment, characterising the attenuation spectral distribution of different fishing lamps and plotting their vertical profiles of light attenuation in seawater; the second one regards the effects of artificial light on fish behaviour were investigated in laboratory conditions, evaluating levels of aggregation, phototaxis and photokinesis in three species of commercial interest: the sea bass (Dicentrarchus labrax), the common grey mullet (Mugil cephalus), and the sea bream (Sparus aurata). All species responded actively to variations in light intensity, and to some extent to lights of different colours. In continuation to this study, we are currently attempting to transfer the approach used in the aquarium to open sea conditions, utilizing echosounder and fixed recording systems to collect the data.
Warm autoimmune hemolytic anemia and hemophagocytic lymphohistiocytosis/macrophage activation syndrome occurring after COVID19 infection and administration of Casirivimab + Imdevimab (COVID19 monoclonal antibody)

Key Clinical Message Warm Autoimmune Hemolytic Anemia (WAHA) is the most common form of autoimmune hemolysis and there is a growing body of evidence of an association between SARS‐CoV‐2 infection, WAHA and a hyperinflammatory state, including hemophagocytic lymphohistiocytosis/macrophage activation syndrome. However, there is no literature to date of WAHA or hyperinflammatory state following administration of anti‐SARS‐CoV‐2 monoclonal antibody treatment. This report documents a case of a patient with history of WAHA who developed brisk hemolysis and a hyperinflammatory state consistent with hemophagocytic lymphohistiocytosis/macrophage activation syndrome after COVID‐19 infection and treatment with an anti‐SARS‐CoV‐2 monoclonal antibody. He was successfully treated with multimodal treatment involving steroids, intravenous immunoglobulins, rituximab, anakinra, and vincristine with resolution of the hemolysis.
Radiographic Anatomy of the Lateral Ankle Ligament Complex: A Cadaveric Study

Background: When lateral ankle sprains progress into chronic lateral ankle instability (CLAI), restoring precise anatomic relationships of the lateral ankle ligament complex (LALC) surgically is complex. This study quantifies the radiographic relationships between the anterior talofibular ligament (ATFL), calcaneofibular ligament (CFL), and prominent osseous landmarks visible under fluoroscopy to assist in perioperative practices for minimally invasive surgery for CLAI. Methods: Ten fresh frozen ankle specimens were dissected to expose the LALC and prepared by threading a radiopaque filament through the ligamentous footprints of the ATFL and CFL. Fluoroscopic images were digitally analyzed to define dimensional characteristics of the ATFL and CFL. Directional measurements of the ligamentous footprints relative to the lateral process of the talus and the apex of the posterior facet of the calcaneus were calculated. Results: Dimensional measurements of the ATFL were a mean length of 9.3 mm, fibular footprint of 9.4 mm, and talar footprint of 9.1 mm. Dimensional measurements of the CFL were a mean length of 19.4 mm, fibular footprint of 8.2 mm, and calcaneal footprint of 7.3 mm. From the radiographic apparent tip of the lateral process of the talus, the fibular attachment of the ATFL was found 13.3 mm superior and 4.4 mm posterior, whereas the talar attachment was found 11.5 mm superior and 4.8 mm anterior. From the radiographic apparent posterior apex of the posterior facet of the calcaneus, the fibular attachment of the CFL was found 0.2 mm inferior and 6.8 mm anterior, whereas the calcaneal attachment was found 14.3 mm inferior and 5.9 mm posterior. Conclusion: The ATFL and CFL were radiographically analyzed using radiopaque filaments to outline the ligamentous footprints in their native locations. These ligaments were also localized with reference to 2 prominent osseous landmarks. These findings may assist in perioperative practices for keyhole incision placement and arthroscopic guidance. Perfect lateral ankle joint imaging with talar domes superimposed is required to be able to do this. Clinical Relevance: Radiographic evaluation of the ATFL and CFL with reference to prominent osseous landmarks identified under fluoroscopy may assist in perioperative practices for minimally invasive surgery to address CLAI for keyhole incision placement and arthroscopic guidance.
Willingness to pay for captive wildlife tourism at the university of Ibadan Zoological Garden, Nigeria

Zoo visits represent a unique opportunity for large numbers of people to be engaged on wildlife conservation issues and given opportunity to support it. The University of Ibadan Zoo is one of the major sites with animals of high intrinsic value and attractions to tourists and other visitors. Copies of structured questionnaire were administered to 165 visitors to the zoo to elicit information on their socio-demography in relation to their paying characteristics, their willingness to pay (WTP) for the services offered by the Zoo, and the factors influencing their WTP. The Result showed that majority (51.5%) of the visitors were males and 48.5% were females. 61% of the visitors had repeated visits while 39% were first time visitors. Although, 76% of them were often willing to pay for captive wildlife tourism in the Zoo, 52% of the visitors were not satisfied with the current charges by the Zoo. Income, marital status and place of residence of the visitors were significantly related to visitors willingness to pay (p<0.05). Five factors significantly influence visitors’ WTP, out of which, the level of satisfaction of the visitors had the highest weighted mean of 4.39, and hence the highest influence on visitors’ WTP. Zoo visitors will be willing to pay more for captive wildlife tourism at the University of Ibadan Zoological Garden, if the facilities, services and conservation strategies are improved to provide more satisfaction to visitors. Keywords: University of Ibadan Zoo, wildlife, visitors, willingness to pay, level of satisfaction
Reverse and Anatomic Shoulder Arthroplasty Regional Usage and Open Payment Analysis Using the Centers for Medicare and Medicaid Services Database

Background This retrospective review aimed to assess if open payments made by industry arthroplasty companies to physicians and hospital systems were significantly affected by implant type and geographic variation. Methods Data was obtained from the Centers for Medicare and Medicaid Services (CMS) publicly available open payment datasets (2016-2019). Geographic locations were identified using regions as defined by the US Census Bureau. A linear regression was calculated to predict the open payment made based on the created variable region, the most used implant type (reverse vs anatomic, n > 30 to be included), and their hypothesized interaction. Results A significant regression equation was found for the hypothesized interaction between implant and region, F(13,11 186) = 3.446, P < . 0001, with an R2 of 0.005. Within the regression, the implant type alone was not significantly related to the open payment (P = .070) but only became significant when paired with the region in the South (US$5807; P < .0001) and West (US$5638; P = .0012) compared to the Northeast. Discussion Our multivariate linear regression model revealed that reverse total shoulder implants were associated with higher open payments, but only within the South and West regions. This indicates that the contributions made by industry arthroplasty companies are a function of both implant and region.
Idiosyncratic Gating of HERG-like K (cid:49) Channels in Microglia

A simple kinetic model is presented to explain the gating of a HERG-like voltage-gated K (cid:49) conductance described in the accompanying paper (Zhou, W., F.S. Cayabyab, P.S. Pennefather, L.C. Schlichter, and T.E. DeCoursey. 1998. J. Gen. Physiol . 111:781–794). The model proposes two kinetically distinct closing pathways, a rapid one favored by depolarization (deactivation) and a slow one favored by hyperpolarization (inactivation). The overlap of these two processes leads to a window current between (cid:50) 50 and (cid:49) 20 mV with a peak at (cid:50) 36 mV of (cid:122) 12% maximal conductance. The near absence of depolarization-activated outward current in microglia, compared with HERG channels expressed in oocytes or cardiac myocytes, can be explained if activation is shifted negatively in microglia. As seen with experimental data, availability predicted by the model was more steeply voltage dependent, and the midpoint more positive when determined by making the holding potential progressively more positive at intervals of 20 s (starting at (cid:50) 120 mV), rather than progressively more negative (starting at 40 mV). In the model, this hysteresis was generated by postulating slow and ultra-slow components of inactivation. The ultra-slow component takes minutes to equilibrate at (cid:50) 40 mV but is steeply voltage dependent, leading to protocol-dependent modulation of the HERG-like current. The data suggest that “deactivation” and “inactivation” are coupled through the open state. This is particularly evident in isotonic Cs (cid:49) , where a delayed and transient outward current develops on depolarization with a decay time constant more voltage dependent and slower than the deactivation process observed at the same potential after a brief hyperpolarization. reducing divalent slow inactivation affecting deactivation.
Risk and protective factors associated with wound infection after neurosurgical procedures: A meta‐analysis

Abstract To systematically evaluate the risk factors for wound infection at the surgical site after neurosurgical craniotomy by meta‐analysis, and to provide an evidence‐based basis for preventing the occurrence of wound infection. A computerised search of PubMed, EMBASE, Cochrane Library, China National Knowledge Infrastructure and Wanfang database was conducted for relevant studies on risk factors for surgical site wound infection after neurosurgical craniotomy published from the database inception to November 2023. Two researchers independently screened the literature, extracted the data and performed quality assessment in strict accordance with the inclusion and exclusion criteria. STATA 17.0 software was applied for data analysis. Overall, 18 papers with 17 608 craniotomy patients were included, of which 905 patients developed wound infections. The analysis showed that underlying diseases [OR = 2.50, 95% CI (1.68, 3.72), p < 0.001] and emergency surgery [OR = 2.47, 95% CI (1.80, 3.38), p < 0.001] were the risk factors for developing wound infections after craniotomy, age < 60 years [OR = 0.72, 95% CI (0.52, 0.98), p = 0.039] was a protective factor for wound infections; whereas sex [OR = 1.11, 95% CI (0.98, 1.27), p = 0.112] and the antimicrobial use [OR = 1.30, 95% CI (0.81 2.09), p = 0.276] were not associated with the presence or absence of wound infection after craniotomy. Underlying disease and emergency surgery are risk factors for developing wound infections after craniotomy, whereas age < 60 years is a protective factor. Clinicians can reduce the occurrence of postoperative wound infections by communicating with patients in advance about the possibility of postoperative wound infections based on these factors, and by doing a good job of preventing postoperative wound infections.