Miracle-dz/UniFAR-FTUs huggingface dataset:
Intestinal String Foreign Body in an Adult Umbrella Cockatoo (Cacatua alba)

Abstract Gastrointestinal foreign bodies are reported in zoo birds, ratites, and juvenile psittacine birds; however, foreign body ingestion by adult psittacine birds is uncommon. We examined an adult umbrella cockatoo (Cacatua alba) because of a 4-month history of weight loss and intermittent, dark brown, malodorous stool. Physical examination findings were unremarkable. Results of laboratory testing revealed anemia, leukocytosis, lymphopenia, monocytosis, hypoproteinemia, and hypoalbuminemia; blood lead and zinc concentrations were not elevated. Enterococcus durans was cultured aerobically from the feces. Gas-filled, dilated intestinal loops and a gas-filled proventriculus were evident on survey radiographs. The clinical signs did not resolve with initial treatment, which included ciprofloxacin, ketoconazole, and a lactobacillus supplement. Over the next 2 months, results of blood tests revealed nonregenerative anemia, intermittent leukocytosis, monocytosis, and hypoproteinemia. Staphylococcus lugdunensis and E faecium were isolated from a crop swab and fecal samples. A barium contrast study revealed a filling defect in the area of the large intestine, whereas results of fluoroscopy were normal. The cockatoo responded poorly to further treatment, including 5 days of supportive care in the hospital, and the owners requested euthanasia. On necropsy, a string foreign body (7 cm long) was found in the proximal large intestine. The string had originated from a rope toy in the bird's cage.
CLINICO-COLONOSCOPIC AND HISTOMORPHOLOGICAL SPECTRUM OF COLONIC DISEASES IN AN ACADEMIC TERTIARY CARE CENTRE

AIMS: Colonoscopic examination is important in the diagnosis and treatment of various suspected colonic diseases. The procedure is used to look for early signs of colorectal cancer. The aims of this study were to correlate colonoscopic findings with the histopathological diagnosis obtained and also to study histopathological features of colonoscopic biopsy specimens. MATERIAL AND METHODS: The study was a retrospective analysis of data between April 2012 and June 2013. 507 colonoscopies were performed during this period. Colonoscopic biopsies showed significant findings on histopathology in 107 patients and were included in the study. The more severe diagnosis was used for analysis when there was more than one colonoscopic finding. All the colonoscopic biopsy specimens were immediately fixed and then routinely processed and embedded. Serial sections were prepared and stained with Hematoxylin and Eosin. Special stains like PAS and Van Gieson stains were used wherever necessary. RESULTS: The clinically significant findings seen on colonoscopy included colorectal cancers, IBD, colonic tuberculosis, strictures, solitary rectal ulcers and polyps. Other relevant findings seen were GI bleed and extrinsic compressions from contiguous structures. Among 107 biopsies, 82 biopsies were non-neoplastic, 25 biopsies were neoplastic. Overall 17 malignant lesions were picked up on histopathology. No significant histopathological findings were detected in biopsies from clinically not relevant colonoscopies. CONCLUSION: Chronic diarrhea and bleeding per rectum were the most common presenting complaints. IBD and malignancy were detected in a significant number of the biopsies. Histopathological diagnosis correlated well with the colonoscopy diagnosis offered. Colonoscopic screening can detect early colonic neoplasms in asymptomatic patients.
Series estimation for single‐index models under constraints

In this paper, a semi‐parametric single‐index model is investigated. The link function is allowed to be unbounded and has unbounded support that answers a pending issue in the literature. Meanwhile, the link function is treated as a point in an infinitely many dimensional function space which enables us to derive the estimates for the index parameter and the link function simultaneously. This approach is different from the profile method commonly used in the literature. The estimator is derived from an optimisation with the constraint of identification condition for the index parameter, which addresses an important problem in the literature of single‐index models. In addition, making use of a property of Hermite orthogonal polynomials, an explicit estimator for the index parameter is obtained. Asymptotic properties for the two estimators of the index parameter are established. Their efficiency is discussed in some special cases as well. The finite sample properties of the two estimates are demonstrated through an extensive Monte Carlo study and an empirical example.
Investigation on the related factors for oral mucositis caused by radiotherapy in nasopharyngeal carcinoma patients with intensity modulated radiotherapy

Objective:To study correlated factors of oral mucositis caused by radiotherapy in nasopharyngeal carcinoma patients with intensity modulated radiotherapy,in order to standard particular nursing steps and reduce the incidence of serious radiogenic stomatitis.Methods:One hundred and fifty patients were investigated and 12 indexes were analyzed by X2 text.Results:All the patients suffered oral mucositis,Ⅱ and above oral mucositis were about 81%. Single factor analysis found that nutrition,smoking,dental heath,oral pH,antibiotics using and chemotherapy were correlated with oral mucositis.Conclusion:Attention should be paid to the patients receiving intensity modulated radiotherapy especially with smoking,antibiotics using and chemotherapy.Preventive nursing during radiogenic or after radiogenic should be strengthened to reduce the incidence and severity of oral mucositis.
On the existence of smooth solutions for fully nonlinear elliptic equations with measurable

We show that for any uniformly elliptic fully nonlinear second-order equation with bounded measurable "coefficients" and bounded "free" term one can find an approximating equation which has a unique continuous and having the second derivatives locally bounded solution in a given smooth domain with smooth boundary data. The approximating equation is constructed in such a way that it modifies the original one only for large values of the unknown function and its derivatives.
Protracted Overexposure to a 137Cs Source: II, Clinical Sequelae

The clinical condition and treatment of a driver who was overexposed to an unshielded 137 Cs source that was in his truck for about 5 months is described. Bone marrow and blood changes are presented as he progressed from pancytopaenia to myelodysplasia with features of refractory anaemia and then anaemia with an excess of blasts and transformation to frank myelomonocytic leukemia. He died about 22 months after the discovery of the source from an overwhelming hepatitis B infection concurrent with immunosuppression following cytostatic treatment for the leukaemia.
Prevalence and Significance of Cytogenetic Findings of Acute Lymphoblastic Leukemia : Experience at King Hussein Medical Center

Objective: To determine the spectrum of cytogenetic abnormalities of acute lymphoblastic leukemia in children and adults at King Hussein Medical Center. Methods: A retrospective review of raw bone marrow aspirate cytogenetic analysis reports was conducted at Princess Iman Research and Laboratory Sciences Center at King Hussein Medical Center during the period between Jan 2010 and Apr 2014. A total of 97 patients were studied regarding: age, gender, and cytogenetic analysis. The age was categorized into two groups (≤14 years as children group and >14 years as adult group). Descriptive analysis using frequencies was used to describe the study variables. Results: Fifty-two (53.6%) cases were males and 45 (46.4%) were females. Their ages ranged between six months and 72 years. A total of 72 (74.2%) patients were children and 25 (25.8%) patients were > 14 years old. Of all pediatric acute lymphoblastic leukemia cases, 52.8% (38 cases) were negative for all the cytogenetic abnormalities, while 47.2% (34 cases) revealed one or more cytogenetic abnormalities. Translocation t(12;21), hyperdiploidy (>50 chromosomes or DNA index >1.16) were the predominant cytogenetic abnormalities in children with lymphoblastic leukemia. In the adult lymphoblastic leukemia group, 68.0% (17 cases) were negative for all the cytogenetic abnormalities, while 32% (8 cases) had cytogenetic abnormalities. Hyperdiploidy was the most common (20.0%, 5 patients) followed by translocation t (9;22) (8.0%, 2 patients). Conclusion: Distribution and patterns of chromosomal abnormalities of lymphoblastic leukemia differ between children and adults. Translocation t(12;21), hyperdiploidy and rearrangements / translocations involving the MLL gene at chromosome 11q23 were the most commonly encountered in children. Hyperdiploidy was prevalent in adults, while no adult cases with 11q23 rearrangements or t(12;21) were encountered.
Weighted Compactifications of Configuration Spaces

In the early 90’s, Fulton and MacPherson provided a natural and beautiful way of compactifying the configuration space F (X,n) of n distinct labeled points in an arbitrary nonsingular variety. In this talk, I will present an alternate compactification of F (X,n), which generalizes the work of Fulton and MacPherson. The construction that I will introduce is parallel to Hassett’s weighted generalization of the moduli space of n-pointed stable curves. After discussing the main properties of this new compactification, I will give a presentation of its intersection ring and as an application, I will describe the intersection ring of Hassett’s spaces in genus 0.
Nonparametric Estimation of Risk-Neutral Distribution via the Empirical
 Esscher Transform

This paper introduces an empirical version of the Esscher transform for nonparametric option pricing. Traditional parametric methods require the formulation of an explicit risk-neutral model and are operational only for a few probability distributions for the returns of the underlying asset. In our proposal, we make only mild assumptions on the price kernel and there is no need for the formulation of the risk-neutral model. First, we simulate sample paths for the returns under the physical measure P. Then, based on the empirical Esscher transform, the sample is reweighted, giving rise to a risk-neutralized sample from which derivative prices can be obtained by a weighted sum of the options’ payoffs in each path. We analyze our proposal in experiments with artificial and real data.
Developmental and neurologic status of children after heart surgery with hypothermic circulatory arrest or low-flow cardiopulmonary bypass.

BACKGROUND Deep hypothermia with either total circulatory arrest or low-flow cardiopulmonary bypass is used to support vital organs during heart surgery in infants. We compared the developmental and neurologic sequelae of these two strategies one year after surgery. METHODS Infants with D-transposition of the great arteries who underwent an arterial-switch operation were randomly assigned to a method of support consisting predominantly of circulatory arrest or a method consisting predominantly of low-flow bypass. Developmental and neurologic evaluations and magnetic resonance imaging (MRI) were performed at one year of age. RESULTS Of the 171 patients enrolled in the study, 155 were evaluated. After adjustment for the presence or absence of a ventricular septal defect, the infants assigned to circulatory arrest, as compared with those assigned to low-flow bypass, had a lower mean score on the Psychomotor Development Index of the Bayley Scales of Infant Development (a 6.5-point deficit, P = 0.01) and a higher proportion had scores < or = 80 (i.e., 2 SD or more below the population mean) (27 percent vs. 12 percent, P = 0.02). The score on the Psychomotor Development Index was inversely related to the duration of circulatory arrest (P = 0.02). The risk of neurologic abnormalities increased with the duration of circulatory arrest (P = 0.04). The method of support was not associated with the prevalence of abnormalities on MRI scans of the brain, scores on the Mental Development Index of the Bayley Scale, or scores on a test of visual-recognition memory. Perioperative electroencephalographic seizure activity was associated with lower scores on the Psychomotor Development Index (P = 0.002) and an increased likelihood of abnormalities on MRI scans of the brain (P < 0.001). CONCLUSIONS Heart surgery performed with circulatory arrest as the predominant support strategy is associated with a higher risk of delayed motor development and neurologic abnormalities at the age of one year than is surgery with low-flow bypass as the predominant support strategy.
An investigation into the use of the method of spherical currents for the determination of scattered wave fields

CHAPTER I: INTRODUCTION 1 (1.1) Methods for the determination of scattered fields 2 (1.2) Summary of contents 10 CHAPTER II: THE METHOD OF SPHERICAL CURRENTS SCALAR CASE 13 (2.1) Basic theory the boundary value problem 13 (2.2) Scattering by sound soft and sound hard spheres 22 (2.3) The computation of spherical Bessel functions and the surfaceand scattered fields of sound hard and sound soft spheres 32 (2.4) The method of spherical currents the surface field 38 (2.5) The scattered field 47 (2.6) The far field 52 CHAPTER III: SCALAR SCATTERING BY A PROLATE SPHEROID 55
Single application of casein phosphopeptide-amorphous calcium phosphate paste-based paste prevents in vitro erosive wear

Aim: The purpose of this study was to evaluate, in vitro, the effect of a single application of a casein phosphopeptide-amorphous calcium phosphate paste (CPP-ACP) in comparison with a fluoride varnish, in enamel of bovine teeth, after erosive challenge using cola soft drink. Materials and Methods: Forty-five enamel specimens were obtained from bovine teeth, selected according to the surface hardness and randomly divided into three groups: G1 - Fluoride varnish, G2 - CPP-ACP-based paste, and G3 - Control, without any treatment. The enamel specimens were treated using each group material and subjected to three daily erosive challenges by immersion of the specimens in cola soft drink for 5 min, during 5 days. Between the erosive cycles, the enamel specimens were immersed in artificial saliva. The initial profilometry (prechallenge) and the final profilometry (postchallenge) were used to evaluate the enamel loss. Statistical Analysis: Data were analyzed using ANOVA and Tukey′s Test (P < 0.05). Results: The single application of CPP-ACP (G2: 4.17 ± 0.77 μm) resulted in less enamel loss compared to control (G3: 4.74 ± 0.52 μm) and higher enamel loss compared to fluoride varnish application (G1: 3.01 ± 0.45 μm) (P < 0.05). Conclusion: The CPP-ACP paste was effective in reducing enamel wear after erosive cycles, however, the best potential for erosion prevention was observed when using the fluoride varnish.
A Prospective Single-arm Open-label Study of Baclofen and Bupropion SR Combination Therapy for Smoking Cessation

ObjectivesTo obtain the initial safety, tolerability, and treatment effect size of combination baclofen and bupropion slow release (SR) for smoking cessation. MethodsA prospective single-arm open-label 7-week trial involving 20 smokers treated with baclofen and bupropion SR, along with brief counseling for smoking cessation. Primary outcome measures included adverse events, tolerability, and smoking cessation. ResultsNo serious adverse effects were reported. The most commonly reported adverse effects were fatigue (40%), disturbance in attention (40%), dry mouth (35%), and insomnia (35%). Combination therapy was well tolerated with 1 (5%) dropout not attributed to medication, and 3 (15%) participants requiring dose reduction for adverse effects. Eleven of 20 participants (55%, SE 11%, 95% confidence interval 32 to 77) achieved continuous abstinence over the final 4 weeks. ConclusionsCombination of baclofen and bupropion SR seems safe and well tolerated with preliminary efficacy for smoking cessation comparing favorably with current first-line smoking cessation aids. The combination of baclofen and bupropion SR may provide an additional treatment option to varenicline or bupropion SR monotherapy. (Health Canada Clinical Trial Registration Control number: 105226).
Substance Abuse Patterns and Psychiatric Symptomology Among Health Care Professionals and Non–Health Care Professionals Evaluated in an Outpatient Program for Impaired Professionals

Objectives:To determine whether health care professionals (HCPs; n=94), evaluated in an outpatient-based program for impaired HCPs and professionals/executives, differed in terms of substance abuse patterns and psychiatric symptomology from their non–health care professional peers (N-HCPs; n=45). Methods:We compared the 2 groups on demographic variables, substance abuse patterns, reported histories of psychiatric comorbidity, and psychological test results using the Personality Assessment Inventory (PAI). Results:The HCPs reported a higher frequency of having past problems with opioids, and also ranked opioids followed by alcohol as their preferred substances, whereas N-HCPs clearly preferred alcohol. The N-HCPs reported higher frequencies of a family history of addiction and mental illness. The N-HCPs reported higher frequencies of suicidal ideation, but there were no differences for past psychiatric history, medications, and health problems. Finally, N-HCPs reported higher PAI clinical scale scores in the moderate to severe ranges at 2 to 4 times the rates as HCPs for the majority of the scales. Conclusions:The HCPs were not significantly different clinically from their N-HCP peers in our program. We question whether specialized programs for impaired HCPs may contribute to feelings of uniqueness which is often cited in the literature as an obstacle to assuming a patient role. The rates of psychiatric comorbidity based on self-report compared with the PAI data support the need for use of psychological testing in the evaluation of impaired HCPs. Implications and suggestions given our findings among this group of HCPs are offered.
A retrospective analysis of presentation and management outcome of proptosis in a tertiary care centre of North-East, India-a case series

Proptosis being a common manifestation of wide variety of diseases inside the orbit and it’s spaces, a dilemma always exists regarding it’s diagnosis and also outcome after surgical or medical management. Twenty two consecutive cases of proptosis of different age groups presenting in a tertiary care centre of northeast India were reviewed ,with regard to their mode of presentation and management outcome. Analysis revealed relative distribution of the different causes of proptosis in the age group of 4years to 86 years. It also highlighted management outcomes in different cases.
The Reliability of the English Version of Ibadan Knee/Hip Osteoarthritis Outcome Measure (IKHOAM)

ABSTRACT Background: The Ibadan Knee/Hip Osteoarthritis Outcome Measure (IKHOAM) an outcome measure developed for evaluating the outcome of therapeutic interventions in patients with knee and/or hip osteoarthritis (OA) in Nigerian clinical settings and similar environment. The aim of this study was to investigate the reliability of the English version of the IKHOAM. Methods: Fifty-four English-speaking patients with OA of knee/hip from physiotherapy clinics of all secondary and tertiary health institutions in Ibadan participated in this cross-sectional survey. The participants completed the self-reported parts of IKHOAM at 48-hr interval. Clinician-measured part of IKHOAM was administered once to each participant by three physiotherapists at the same time and for a second time by one of the physiotherapists after 48 hr. Data were summarized using descriptive statistics (mean, standard deviation, and percentage) and analyzed using intraclass correlation coefficient and Spearman rank order correlation. Results: The test–retest reliability for patient measured ranged from 0.94–0.99 (p < 0.01), while the intrarater reliability and interrater reliability for the clinician measured of the English version of the IKHOAM were 0.96 (p < 0.05) and 0.60 (p < 0.05), respectively. Conclusion: The English version of the IKHOAM is a reliable outcome measure, and it is recommended for integration in the assessment of patients with knee and/or hip OA in Nigerian clinical settings and similar environment.
Evaluation of Liver Function Test in Normal Pregnancy and Pre- eclampsia: A Case Control

Background and Objective: Preeclampsia is a multi system disorders that can affect every maternal organ predominantly the cardio-vascular system, kidneys, brain and liver. The present study was conducted to compare the liver function tests in preeclampsia with normotensive pregnancy. Methodology: The present case control study was carried out at the department of obstetrics and gynaecology of Bankura Sammilani Medical College, Bankura to find the serum bilirubin and serum levels of liver enzymes ALT, AST and ALP in 100 pregnant women (50 preeclampsia and 50 normotensive pregnant women). Results: The mean BMI of cases was 28.02 ± 3.67kg/m 2 and that of control was 24.48±3.09 kg/m 2 . The mean value of serum bilirubin in cases was
Assessment of knowledge and attitude of Rural Population about HIV/AIDS in Raigad District, India

Objective: To assess the knowledge and attitude of rural population about HIV/AIDS in Raigad district. Material and Methods: A descriptive epidemiological study was conducted during January 2009 to April 2009 at Mahad Taluka of Raigad District, India. Total of 724 individuals were selected by using stratified random sampling. The information was gathered by personal interview using semi-structured proforma. Results: Total 724 individuals were interviewed with 202 (27.9%) males and 522 (72.1%) females. Overall awareness about symptoms of HIV/AIDS, its transmission routes and preventive measures was very poor. 383(52.9%) individual knew correct routes of transmission while only 289 (39.9%) individuals knew how to prevent HIV infection transmission. 317 (43.8%) individual never heard about condom and 117 (17.2%) population knew correct purpose of condom. Composite scores of Knowledge and attitude were low (below 50%) specifically in females, unmarried and illiterate individuals. Conclusion: Thus the knowledge of rural people about HIV / AIDS, its transmission and prevention should be improved with help of vigorous campaigning, training workshops, HIV / AIDS education sessions with special focus on migrant workers and their families.