Miracle-dz/UniFAR-FTUs huggingface dataset:
Eribulin-induced radiation recall dermatitis: a case report and brief review of the literature

Background Radiation recall (RR) is a fairly uncommon and unpredictable phenomenon caused by an acute inflammatory reaction in a previously irradiated area. Several antineoplastic drugs have been previously associated with RR reactions including anthracyclines and taxanes like docetaxel, paclitaxel or antimetabolites. Case presentation Here we report for the first time a case of a recall reaction to Eribulin mesylate, a novel chemotherapeutic compound that affects microtubule polymerisation, approved for the treatment of metastatic or locally advanced breast cancers (BCs). We present the case of a 61-year-old female BC patient originally diagnosed with bilateral BC with metastatic disease that went through several lines of chemotherapy and radiation therapy (RT); RR reaction was observed following Eribulin treatment and sequential palliative RT. Conclusion This case report raises awareness about these fairly rare phenomena when prescribing Eribulin, or any new chemotherapeutic after RT to prevent and treat as early as possible to avoid further patient complications.
Access to treated water in utero and childhood well-being : Evidence from rural China

This paper examines the impacts of in utero access to treated water on childhood health. We exploit the variation in the timing of tap water connection across communities imposed by a major drinking water program in rural China. Using data extracted from the China Family Panel Studies 2010, we find that prenatal access to treated water significantly raises 2-11 year-old children’s height by 0.239 standard deviations and reduces the probability of at least three doctor visits the previous year by 9.0 percentage points. The height increase is likely to be more for children of less educated mothers. Event study estimates confirm that prenatal period is the crucial window for the impact on health. Mechanism analysis suggests that the health benefits may stem from the improvement in drinking water quality, rather than the increase in water quantity.
Effect of Some Thermal Processing Techniques on the Anti- nutritional Factors of Canavalia plagiosperma Piper Seeds

The effect of some thermal processing techniques on the anti-nutritional factors of Canavalia plagiosperma Piper seeds was studied. Raw seeds of Canavalia plagiosperma Piper (Oblique- seeded Jack bean) were autoclaved (at 121°C, 15 psi for 25, 30 and 35 minutes), cooked (at 100°C for 30, 40 and 50 minutes) and roasted (at 120°C for 40, 60 and 80 minutes). The anti-nutritional factors of the processed and raw samples were determined. Six (6) anti-nutrients (alkaloid: 1.17%, haemagglutinin: 20.31 Hu/mg, hydrogen cyanide: 4.70 mg/kg, raffinose: 0.64%, stachyose: 1.09%, steroid: 0.38%) were determined in the raw seed. The three processing treatments given to the seed showed a general reduction trend on these six anti-nutrients at different rates and levels. From the results, autoclaving was the best processing method for haemagglutinin (0.05 Hu/mg), raffinose (0.06%), stachyose (0.22%) and steroid (0.02%) while cooking was the best processing treatment for alkaloid (0.04%) and hydrogen cyanide (0.83 mg/kg). Roasting had the least reduction effect on the six anti- nutrients investigated. The results, therefore, suggest that moist heat treatments (autoclaving and cooking) significantly lowered the levels of antinutrients in Canavalia plagiosperma Piper seeds, thereby making it safer for consumption.
Application of Extreme Value Theory and Fundamental Analysis in Long-Short Strategies: an Analysis of Pair Tradings in The Brazilian Market

In recent decades, the number of funds has increased which aim to explore market inefficiencies through arbitrage strategies, among which the long-short strategy stands out. A large part of the analyses used to obtain the pair tradings, however, does not consider the extreme deviations that exist in the interdependence process between the assets involved and the firms’ operational quality indicators. The Extreme Value Theory and Fundamental Analysis were used in this study to model the series of the asset pair price indices obtained based on the accounting indicator structure proposed by Piotroski (2000). These approaches permitted considering companies with positive signs of profitability, an operational capital structure and efficiency, besides distributions that are capable of capturing the extreme co-movements associated with the selected pair tradings. Based on this model, a new quantitative approach was created for the long-short strategy, called the GEV Long-Short. The obtained results suggest that the best adjustment of the extreme quantiles through the extreme value distribution can provide more refined probabilistic support for the return to the average to justify the possibility of long-short arbitrage.
Encouraging Pro-Environmental Behaviors Through Children-Based Appeals: A Kin Selection Perspective

Environmental problems are due to the fact of humans prioritizing their narrow personal interests over collective interests. How can pro-environmental behavior be promoted without requiring people to behave in ways that go against their selfish tendencies? Kin selection theory asserts that humans are predisposed to ensure the survival and replication of their genes which they share with their offspring. We hypothesized that appeals to the welfare of their children would foster pro-environmental decision-making through activating a parental care motivation. Four studies examined the impact of messages about the welfare of (potential) children on environmental intentions. Overall, the results show that children-based appeals indirectly fostered ecological intentions through an increased parental care motivation. Furthermore, meta-analyses triangulated these findings by showing that people with children show greater parental care and pro-environmental intentions. These results are discussed in light of the kin selection theory, and its implications for environmental policymaking are addressed.
Impact of Using Different Levels of Threshold-Based Artefact Correction on the Quantification of Heart Rate Variability in Three Independent Human Cohorts

Heart rate variability (HRV) is a non-invasive indicator of autonomic nervous system function. HRV recordings show artefacts due to technical and/or biological issues. The Kubios software is one of the most used software to process HRV recordings, offering different levels of threshold-based artefact correction (i.e., Kubios filters). The aim of the study was to analyze the impact of different Kubios filters on the quantification of HRV derived parameters from short-term recordings in three independent human cohorts. A total of 312 participants were included: 107 children with overweight/obesity (10.0 ± 1.1 years, 58% men), 132 young adults (22.2 ± 2.2 years, 33% men) and 73 middle-aged adults (53.6 ± 5.2 years, 48% men). HRV was assessed using a heart rate monitor during 10–15 min, and the Kubios software was used for HRV data processing using all the Kubios filters available (i.e., 6). Repeated-measures analysis of variance indicated significant differences in HRV derived parameters in the time-domain (all p < 0.001) across the Kubios filters in all cohorts, moreover similar results were observed in the frequency-domain. When comparing two extreme Kubios filters, these statistical differences could be clinically relevant, e.g. more than 10 ms in the standard deviation of all normal R-R intervals (SDNN). In conclusion, the results of the present study suggest that the application of different Kubios filters had a significant impact on HRV derived parameters obtained from short-term recordings in both time and frequency-domains.
Crystal chemistry of Cu-bearing tourmalines

Abstract The crystal structures of two elbaites from the Paraiba deposit with copper contents of 3.51 and 1.61 wt% CuO [a = 15.881(1), 15.840(3); c = 7.112(1), 7.1028(9), respectively], as well as a synthetic Cu-bearing olenite with a CuO content of 8.39 wt% [a = 15.840(4), c = 7.091(1)] have been refined to R-indices of 2.2, 3.1, and 4.1% using X‑ray single-crystal diffraction. On the basis of original and published data (for six structures) the crystal-chemical relationships of copper-bearing tourmalines has been analyzed. It is shown that copper cations and cations of other 3d elements (Mn, Zn, Fe) occupy almost exclusively the Y site. Such an ordered distribution results in a change of the size of the Y-octahedra. There is an inverse correlation between the content of 3d elements (mainly Cu2+ cations) and Al3+ cations in the Y-octahedron and also between the value of and the content of Al3+ cations in the Y site. The direct correlation between values of -distance in the structures of Cubearing elbaites and the parameters (a, c) of the unit cell have been found. Distortions of polyhedra in the structures of Cu-bearing elbaites are similar, and significantly higher than those present in the structure of the synthetic Cu-bearing olenite.
Effects of starter feeding time on growth of Yangzhou geese.

1 SUMMARY An experiment was conducted to investigate effects of starter feeding time on growth and development of Yangzhou geese. A total of 480 Yangzhou geese of similar weight were selected and randomly assigned to four groups according to four feeding schedules (fasting for 12, 24, 36 and 48 h posthatch ), designated respectively as group 1, 2, 3, 4. Each group of 120 birds comprised of four replicate subgroups with 30 geese per group comprising of 15 males and 15 females. After fasting, all birds were provided with feedstuff ad libitum until 28 d of age. At 12h, 36h, 60h, 108h, 156h, 14d, 21d and 28d posthatch, two geese (1 male and 1 female) per replicate of each experimental group were randomly selected and individually weighed. Gizzard, small intestine, heart, liver, pancreas, spleen, and bursa of Fabricus of each goose were taken out and weighed. Results showed that initial food deprivation reduced body weight (BW) of experimental geese, with less BW realized as the fasting period was prolonged. At 28 d of age, BW of the first three groups of geese (fasted for 12-36h) was significantly higher (P 0.05). Results of the present study demonstrated that the maximum fasting period with no significantly negative effect on final performance was 36 h posthatch. Therefore, to ensure good performance, Yangzhou geese should be fed within 36h posthatch.
Mapping the Design Space of a Recuperated, Recompression, Precompression Supercritical Carbon Dioxide Power Cycle with Intercooling, Improved Regeneration, and Reheat

A real fluid heat engine power cycle analysis code has been developed for analyzing the zero dimensional performance of a recuperated, recompression, precompression supercritical carbon dioxide power cycle with intercooling, improved regeneration, and reheat. Variation in fluid properties within the heat exchangers is taken into account by discretizing zero dimensional heat exchangers. Variation in performance with respect to design heat exchanger pressure drops, precompressor pressure ratio, main compressor pressure ratio, recompression mass fraction, main compressor inlet pressure, and low temperature recuperator mass fraction have been explored throughout a range of each design parameter. Real turbomachinery efficiencies are implemented and the sensitivity of the cycle performance and the optimal design parameters is explored. Sensitivity of the cycle performance and optimal design parameters is also studied with respect to the minimum heat rejection temperature and the maximum heat addition temperature. An interactive web based tool has been developed for analyzing the performance of the entire design space in greater detail as well as plotting temperature difference within the heat exchangers.
A POWERED LIFT DESIGN FOR SUBSONIC CIVIL TRANSPORT AIRCRAFT

It has been suggested that the basic configuration of subsonic civil transport aircraft is nearing its full evolutionary potential and a departure in the form of a new configuration or technology is needed. In this paper a jet-flap type powered lift design is being evaluated and then compared to blended wing-body and other advanced technology designs.
Fighting the Hydra: Optimizing treatment for type 2 diabetes

This thesis focused on optimizing treatment for type 2 diabetes. We evaluated short-term risk (hypoglycaemia) and long-term risk (cancer) of sulfonylurea derivatives and insulin and reviewed the (dis)advantages of the long-acting insulin analogues, insulin glargine and insulin detemir. Furthermore, we evaluated strategies to optimize insulin dose titration. In particular we investigated the feasibility, safety and effectiveness of an e-health application with computerised decision support to support patients in performing insulin titration.
Non-Market Interactions and Entry into Export Markets

Previous research suggests that …rms that penetrate foreign markets reduce entry costs for other potential exporters, generating export spillovers. This paper continues this line of research by developing a general empirical framework to study whether export participation decisions at the …rm level are in‡uenced by the characteristics of …rms that belong to a common reference group (de…ned by industry and geographical region). It is shown that, in the presence
Buying Peace: The Mirage of Demobilizing Rebels O. D’Aoust, O. Sterck and Ph. Verwimp

In 2009, hostilities were brought to an end in Burundi when the FNL rebel group laid down weapons. In exchange for peace, ex-rebels benefited from a disarmament, demobilization and reintegration (DDR) program to finance their return to civilian life. A few years earlier, another rebel group (CNDD-FDD) had gone through the same program. In this paper, we assess the impact of this complex program from a theoretical and an empirical viewpoint. First, we develop an agricultural model in order to predict the impact of demobilization cash transfers on beneficiary and non-beneficiary households. Then, we test the theoretical model by using a household panel dataset collected in rural Burundi. We find that, in the short run, the cash payments received by ex-combatants had a positive direct impact on purchases and investments of beneficiaries, as well as an indirect positive impact on non-beneficiaries. We also find that the direct and indirect impacts on purchases vanish in the long run. These results suggest that reinsertion grants may favour the acceptation of ex-combatants in their local communities in the short run, but are most likely not sufficient for peace to hold. More generally, it emphasizes the importance of considering spillovers in the evaluation of development programs.
Investigations into the in situ Enterococcus faecalis biofilm removal by passive and active sodium hypochlorite irrigant delivered into lateral canal of a simulated root canal model

1 Division of Biomaterials and Tissue Engineering, UCL Eastman Dental Institute, University College London, London, United Kingdom. Postal address: 256 Grays Inn Road, London WC1X 8LD E-mails: Saif.mohmmed. 12@ucl.ac. uk n.mordan@ucl.ac. uk j.knowles@ucl.ac. uk 2 School of Dentistry, College of Biomedical and Lifesciences, Department of Learning and Scholarship, Cardiff University, Cardiff, United Kingdom. Postal address: Heath Park Campus, Cardiff CF14 4XY Email: ViannaM@cardiff.ac. uk 3 School of Pharmacy, Faculty of Life Sciences, University College London, London, United Kingdom. Postal address: 406, 29-39 Brunswick Square, London WC1N 1AX E-mail: matthew.penny@ucl.ac. uk s.hilton@ucl.ac. uk
The Power of Positive Psychological Capital: An Exploratory Study

Purpose: The main purpose of this study is to explore the psychological construct; whether this construct (hope, strength, optimism and efficiency) have a relationship with task performance and employee turnover. Design/methodology: This study used qualitative method and semi structured interviews were conducted in order to obtain data from banking sectors. NVIVO Software was used to utilizing semi structure interviews. Findings: The results show that positive psychological capital positively relevant to their task performance at work, and negatively related to turnover. Practical Implications: The benefits arising from this study is organization and staff to provide a good climate of positive development in order to develop positive psychological capital. Originality: This study explores the spectacle of positive psychological capital; development must be integrated into the programs and organization of human resources and performance management development. Citation: Akhtar F, Khan H, Rasheed M (2019) The Power of Positive Psychological Capital: An Exploratory Study. Arabian J Bus Manag Review 9: 387.
Verification and Validation: High Charge and Energy (Hze) Transport Codes and Future Development

In the present paper, we give the formalism for further developing a fully three-dimensional HZETRN code using marching procedures but also development of a new Green's function code is discussed. The final Green's function code is capable of not only validation in the space environment but also in ground based laboratories with directed beams of ions of specific energy and characterized with detailed diagnostic particle spectrometer devices. Special emphasis is given to verification of the computational procedures and validation of the resultant computational model using laboratory and spaceflight measurements. Due to historical requirements, two parallel development paths for computational model implementation using marching procedures and Green s function techniques are followed. A new version of the HZETRN code capable of simulating HZE ions with either laboratory or space boundary conditions is under development. Validation of computational models at this time is particularly important for President Bush s Initiative to develop infrastructure for human exploration with first target demonstration of the Crew Exploration Vehicle (CEV) in low Earth orbit in 2008.
Equilibria in Health Exchanges: Adverse Selection vs. Reclassification Risk

This paper studies regulated health insurance markets known as exchanges, motivated by their inclusion in the Affordable Care Act (ACA). We use detailed health plan choice and utilization data to model individual-level projected health risk and risk preferences. We combine the estimated joint distribution of risk and risk preferences with a model of competitive insurance markets to predict outcomes under different regulations that govern insurers' ability to use health status information in pricing. We investigate the welfare implications of these regulations with an emphasis on two potential sources of inefficiency: (i) adverse selection and (ii) premium reclassification risk. We find that market unravelling from adverse selection is substantial under the proposed pricing rules in the Affordable Care Act (ACA), implying limited coverage for individuals beyond the lowest coverage (Bronze) health plan permitted. Although adverse selection can be attenuated by allowing (partial) pricing of health status, our estimated risk preferences imply that this would create a welfare loss from reclassification risk that is substantially larger than the gains from increasing within-year coverage, provided that consumers can borrow when young to smooth consumption or that age-based pricing is allowed. We extend the analysis to investigate some related issues, including (i) age-based pricing regulation (ii) exchange participation if the individual mandate is unenforceable and (iii) insurer risk-adjustment transfers.
Measuring Heart Rate Variability Using Commercially Available Devices in Healthy Children: A Validity and Reliability Study

Heart rate variability (HRV) is an accepted method for determining autonomic nervous system activity and cardiovascular risk in various populations. This study assessed the validity and reliability of a commercially available finger photoplethysmography (PPG) system for measuring pediatric HRV in a real-world setting. Sixteen healthy children (4.06 ± 0.58 years) were recruited. The PPG system was compared to the Polar H10 heart rate (HR) sensor validated against ECG (gold standard) for HRV measurement. Seated short-term resting R-R intervals were recorded simultaneously using both systems. Recordings were performed on 3 days at the participants’ school. Paired t-tests, effect sizes and Bland–Altman analyses determined the validity of the PPG system. The relative and absolute reliability of both systems were calculated. No HRV parameters were valid for the PPG system. Polar H10 yielded moderate (0.50–0.75) to good (0.75–0.90) relative reliability with R-R intervals and the standard deviation of instantaneous and continuous R-R variability ratio showing the best results (ICCs = 0.84). Polar H10 displayed better absolute reliability with the root mean square of successive differences, R-R intervals and HR showing the lowest values (TEM% < 12%). The use of the Polar H10 and not the PPG system is encouraged for HRV measurement of young children in an educational real-world setting.
TRENDS IN URBAN FORESTRY PRACTICES, PROGRAMS, AND SUSTAINABILITY: CONTRASTING A PENNSYLVANIA, U.S., STUDY

Previous studies provided criteria and guidelines both for measuring and increasing the sustainability of urban forests. These studies have also provided evidence that difficulties existed in completing important practices (e.g., inventories, street tree ordinances, management plans), which contribute to both better urban forest programs and sustainability. In a recent study of both small town tree commissions and programs in northeastern Pennsylvania U.S., there was a marked difference between tree commission members' attitudes toward urban forestry practices and the successful completion of them. Focus groups composed of tree commission members were used to gather information on why these differences existed. Our northeastern Pennsylvania study provided evidence that local tree commissions had difficulties completing urban forestry practices for a number of reasons, including a lack of volunteer time and a need for additional support and assistance. The study also showed that small town tree commissioners viewed and defined urban forest sustainability much more practically than has been ex- pressed in the extant literature. Questions continue about how well local urban forestry practices support sustainable urban forest programs and resources.
Limited Non-Preemptive EDF Scheduling for a Real-Time System with Symmetry Multiprocessors

In a real-time system, a series of jobs invoked by each task should finish its execution before its deadline, and EDF (Earliest Deadline First) is one of the most popular scheduling algorithms to meet such timing constraints of a set of given tasks. However, EDF is known to be ineffective in meeting timing constraints for non-preemptive tasks (which disallow any preemption) when the system does not know the future job release patterns of the tasks. In this paper, we develop a scheduling algorithm for a real-time system with a symmetry multiprocessor platform, which requires only limited information about the future job release patterns of a set of non-preemptive tasks, called LCEDF. We then derive its schedulability analysis that provides timing guarantees of the non-preemptive task set on a symmetry multiprocessor platform. Via simulations, we demonstrate the proposed schedulability analysis for LCEDF significantly improves the schedulability performance in meeting timing constraints of a set of non-preemptive tasks up to 20.16%, compared to vanilla non-preemptive EDF.