Miracle-dz/UniFAR-FTUs huggingface dataset:
Lichenomphalia meridionalis, an agaricoid basidiolichen species new to Central Europe

Abstract: Nagy, J., Németh, Cs. , Dima, B. & Papp, V. 2020. Lichenomphalia meridionalis, an agaricoid basidiolichen species new to Central Europe. – Herzogia 33: 25 –33. A new finding of the agaricoid basidiolichen, Lichenomphalia meridionalis is reported from Hungary (Central Europe). This species was originally known only from the Mediterranean regions of Europe, but recently it has also been found in Japan. The nrITS and nuLSU (28S) rDNA sequences, macro- and, microscopical characteristics and photographs of the Hungarian specimen are given.
Cocaine-Dependent Acquisition of Locomotor Sensitization and Conditioned Place Preference Requires D1 Dopaminergic Signaling through a Cyclic AMP, NCS-Rapgef2, ERK, and Egr-1/Zif268 Pathway

Elucidation of the mechanism of dopamine signaling to ERK that underlies plasticity in dopamine D1 receptor-expressing neurons leading to acquired cocaine preference is incomplete. NCS-Rapgef2 is a novel cAMP effector, expressed in neuronal and endocrine cells in adult mammals, that is required for D1 dopamine receptor-dependent ERK phosphorylation in mouse brain. In this report, we studied the effects of abrogating NCS-Rapgef2 expression on cAMP-dependent ERK→Egr-1/Zif268 signaling in cultured neuroendocrine cells; in D1 medium spiny neurons of NAc slices; and in either male or female mouse brain in a region-specific manner. NCS-Rapgef2 gene deletion in the NAc in adult mice, using adeno-associated virus-mediated expression of cre recombinase, eliminated cocaine-induced ERK phosphorylation and Egr-1/Zif268 upregulation in D1-medium spiny neurons and cocaine-induced behaviors, including locomotor sensitization and conditioned place preference. Abrogation of NCS-Rapgef2 gene expression in mPFC and BLA, by crossing mice bearing a floxed Rapgef2 allele with a cre mouse line driven by calcium/calmodulin-dependent kinase IIα promoter also eliminated cocaine-induced phospho-ERK activation and Egr-1/Zif268 induction, but without effect on the cocaine-induced behaviors. Our results indicate that NCS-Rapgef2 signaling to ERK in dopamine D1 receptor-expressing neurons in the NAc, but not in corticolimbic areas, contributes to cocaine-induced locomotor sensitization and conditioned place preference. Ablation of cocaine-dependent ERK activation by elimination of NCS-Rapgef2 occurred with no effect on phosphorylation of CREB in D1 dopaminoceptive neurons of NAc. This study reveals a new cAMP-dependent signaling pathway for cocaine-induced behavioral adaptations, mediated through NCS-Rapgef2/phospho-ERK activation, independently of PKA/CREB signaling. SIGNIFICANCE STATEMENT ERK phosphorylation in dopamine D1 receptor-expressing neurons exerts a pivotal role in psychostimulant-induced neuronal gene regulation and behavioral adaptation, including locomotor sensitization and drug preference in rodents. In this study, we examined the role of dopamine signaling through the D1 receptor via a novel pathway initiated through the cAMP-activated guanine nucleotide exchange factor NCS-Rapgef2 in mice. NCS-Rapgef2 in the NAc is required for activation of ERK and Egr-1/Zif268 in D1 dopaminoceptive neurons after acute cocaine administration, and subsequent enhanced locomotor response and drug seeking behavior after repeated cocaine administration. This novel component in dopamine signaling provides a potential new target for intervention in psychostimulant-shaped behaviors, and new understanding of how D1-medium spiny neurons encode the experience of psychomotor stimulant exposure.
The structure of the RCAN1:CN complex explains the inhibition of and substrate recruitment by calcineurin

This study shows how RCAN1, a key protein in Down syndrome and Alzheimer’s disease, modulates CN function. Regulator of calcineurin 1 (RCAN1) is an endogenous inhibitor of the Ser/Thr phosphatase calcineurin (CN). It has been shown that excessive inhibition of CN is a critical factor for Down syndrome and Alzheimer’s disease. Here, we determined RCAN1’s mode of action. Using a combination of structural, biophysical, and biochemical studies, we show that RCAN1 inhibits CN via multiple routes: first, by blocking essential substrate recruitment sites and, second, by blocking the CN active site using two distinct mechanisms. We also show that phosphorylation either inhibits RCAN1-CN assembly or converts RCAN1 into a weak inhibitor, which can be reversed by CN via dephosphorylation. This highlights the interplay between posttranslational modifications in regulating CN activity. Last, this work advances our understanding of how active site inhibition of CN can be achieved in a highly specific manner. Together, these data provide the necessary road map for targeting multiple neurological disorders.
Arthropods visiting flowers of Aristolochia californica Torr. (Aristolochiaceae)

Abstract. A survey of arthropods visiting flowers of California pipevine, Aristolochia californica Torr. (Aristolochiaceae), was conducted during 2017 and 2018. Collecting produced 1725 individuals in 75 terminal taxa. Over the two years, a residential backyard produced more terminal taxa (70) and individuals (1539) than flowers in an upland grassland (27 terminal taxa, 186 individuals). Diptera: Mycetophilidae were the dominate arthropod group attracted to the flowers, accounting for 77.8% of visitors and represented by 17 genera and 28 morphospecies, with Mycetophila Meigen, 1803 being most diverse with 12 morphospecies. The superfamily Sciaroidea (Keroplatidae, Mycetophilidae, Sciaridae) had 33 morphospecies and 1505 specimens representing 87.2% of the total arthropods. The arthropods could be grouped into the following guilds: potential pollinators, fluid feeders, predators, parasites, scavengers and temporary residents.
Fast CU Partition and Intra Mode Decision Method for H.266/VVC

The Versatile Video Coding (H.266/VVC) standard has developed by Joint Video Exploration Team (JVET). Compared with the previous generation video coding standard, the H.266/VVC is more outstanding. Since the H.266/VVC introduces multi-type tree (MTT) structure including binary tree (BT) and ternary tree (TT), which brings the significant coding efficiency but increases coding complexity. Moreover, the intra prediction modes have increased from 35 to 67, which can provide more accurate prediction than H.265/High Efficiency Video Coding (HEVC). Therefore, these can improve the encoding quality, but increase computational complexity. To reduce the computational complexity, this paper designs a fast coding unit (CU) partition and intra mode decision algorithm, which includes fast CU partition based on random forest classifier (RFC) model and fast intra prediction modes optimization based on texture region features. Simulation results indicate that the proposed scheme can save 54.91% encoding time with only 0.93% increase in BDBR.
The Effect of Group Size on the Responses of Wood Frog Tadpoles to Fish

ABSTRACT In many species of anurans, tadpoles adjust their behavior in the presence of fish or fish cues, in many cases reducing their activity. Tadpoles may also adjust their activity or behavior in response to group size. We examined the effects of predator cues (bluegill sunfish, Lepomis macrochirus) and group size on the behavior of Wood Frog (Rana sylvatica) tadpoles in a factorial laboratory experiment. Wood Frog tadpoles were less active and used the vegetated side of the experimental aquaria more in the presence of fish. Group size alone had no effect on the behavior of the Wood Frog tadpoles in our experiments. Our experiment shows that cues from fish predators have a greater influence on the behavior of Wood Frog tadpoles than does group size, at least in the range of group sizes used in this experiment.
Greenhouse gas fluxes from tropical peatlands in south‐east Asia

The lowland peatlands of south‐east Asia represent an immense reservoir of fossil carbon and are reportedly responsible for 30% of the global carbon dioxide (CO2) emissions from Land Use, Land Use Change and Forestry. This paper provides a review and meta‐analysis of available literature on greenhouse gas fluxes from tropical peat soils in south‐east Asia. As in other parts of the world, water level is the main control on greenhouse gas fluxes from south‐east Asian peat soils. Based on subsidence data we calculate emissions of at least 900 g CO2 m−2 a−1 (∼250 g C m−2 a−1) for each 10 cm of additional drainage depth. This is a conservative estimate as the role of oxidation in subsidence and the increased bulk density of the uppermost drained peat layers are yet insufficiently quantified. The majority of published CO2 flux measurements from south‐east Asian peat soils concerns undifferentiated respiration at floor level, providing inadequate insight on the peat carbon balance. In contrast to previous assumptions, regular peat oxidation after drainage might contribute more to the regional long‐term annual CO2 emissions than peat fires. Methane fluxes are negligible at low water levels and amount to up to 3 mg CH4 m−2 h−1 at high water levels, which is low compared with emissions from boreal and temperate peatlands. The latter emissions may be exceeded by fluxes from rice paddies on tropical peat soil, however. N2O fluxes are erratic with extremely high values upon application of fertilizer to wet peat soils. Current data on CO2 and CH4 fluxes indicate that peatland rewetting in south‐east Asia will lead to substantial reductions of net greenhouse gas emissions. There is, however, an urgent need for further quantitative research on carbon exchange to support the development of consistent policies for climate change mitigation.
The Roles of Social Value Orientation and Anticipated Emotions in Intergroup Resource Allocation Decisions

How individuals divide resources between themselves and another person is influenced both by their social value orientation (SVO) and the emotions they expect to feel when dividing resources (anticipated emotions). Research has also shown that individuals favor members of their own group (ingroup) over individuals from other groups (outgroup) when allocating resources. The Malaysian multi-ethnic population is a highly relevant context to study the combined effects of intergroup relations and SVO on anticipated emotions and resource allocation. The current studies recruited Malaysian participants to examine whether anticipated emotions and allocation behavior are influenced by the ethnic identity of the person receiving the allocation. Participants completed an SVO measure and rated how they would feel if they were to share resources equally or unequally. They then made allocations between themselves and an ingroup or outgroup member in an economic game. There was no evidence of ingroup favoritism in anticipated emotions and allocation behavior. This may have been due to impression management, social desirability concerns, and/or the use of a population with socially liberal attitudes. The results nevertheless provide support for the notion that anticipated emotions play a key role in resource allocation decisions.
Bisphenol A Diglycidyl Ether (BADGE) and Progesterone Do Not Induce Ca2+ Signals in Boar Sperm Cells

Aim Exposure of boar sperm cells to Bisphenol A diglycidyl ether (BADGE) has been shown to lead to reproductive failure in sows, however, the mode of action is unknown. As we have recently shown that BADGE can interfere with Ca2 + signaling in human sperm cells through an action on CatSper, and as CatSper has been shown to be expressed in boar sperm cells, we hypothesized that a similar mechanism in the boar sperm cells could be responsible for the reproductive failure. Methods Direct effects of BADGE and the endogenous ligand of human CatSper, progesterone, on Ca2+ signaling in human and boar sperm cells were evaluated side-by-side using a Ca2+ fluorimetric assay measuring changes in intracellular Ca2+. Effects of BADGE on Ca2+ signaling in boar sperm were furthermore assessed by flow cytometry by an independent laboratory. Results The exact same solutions of BADGE and progesterone induced transient biphasic Ca2+ signals in human sperm cells, but failed to do so in both non-capacitated and capacitated boar sperm cells. BADGE also failed to induce transient biphasic Ca2+ signals in boar sperm cells in the flow cytometric assay. Conclusion BADGE and progesterone failed to induce Ca2+ signals in boar sperm cells. This indicates that the signaling mechanisms leading to activation of CatSper differs between human and boar sperm cells, and suggests that the mode of action by which exposure of boar sperm cells to BADGE can lead to reproductive failure in sows does not involve effects on Ca2+ signaling.
Residential Segregation and Social Trust of Immigrants and Natives: Evidence From the Netherlands

This study examines the relationship between residential segregation and social trust of immigrants and natives in the Netherlands. Building on previous studies that have found evidence for a negative segregation-trust link, we present a nuanced narrative by (i) distinguishing between an ethnic minority and majority perspective, (ii) elaborating theoretical foundations on the moderating role of individual exposure in the form of ethnic minority concentration in the neighborhood, and (iii) taking income segregation into account. In addition to the refined theoretical framework, our study employs a rigorous empirical approach. Using two waves (2009 and 2013) of the Netherlands Longitudinal Lifecourse Study—a geocoded panel study with an oversampling of Moroccan and Turkish immigrants—we are able to study the influence of (changes in) municipality-level segregation patterns for both natives and immigrants, and consider the roles of both neighborhood ethnic minority concentration, as well as income-based segregation. Results from four-level multilevel models show that ethnic segregation is negatively related to the social trust of immigrants. At the same time, this negative relationship is particularly strong in neighborhoods with a low level of minority population concentration, which provides support for the so-called integration paradox where negative intergroup interactions reduce social trust. For respondents of Dutch origin, we find no evidence that their social trust is sensitive to ethnic segregation or that this relationship is conditional on minority concentration at the neighborhood level.
A New Dwarf Forest Chameleon from the Udzungwa Mountains of Tanzania, East Africa, (Squamata: Rhampholeon Günther, 1874)

Abstract A new species of Rhampholeon from the montane and submontane escarpment forests of the Udzungwa Mountains is described. This pigmy chameleon has a maximum total length of 64 mm and bears a close morphological resemblance to Rhampholeon uluguruensis, differing mainly by possessing finer cranial scalation and more thornlike hemipenal papillae arranged in two proximal rows of four (occasionally five) and two followed by a single terminal row of four (occasionally five) papillae. The only known populations of this species are found in Udzungwa escarpement forests between 1200 and 2000 m a.s. l. The zoogeography and systematics of related species of the genus Rhampholeon in the Eastern Arc Mountains of Tanzania and Malawi are reviewed and an updated key to the Genus Rhampholeon is presented.
Germination and proteome analyses reveal intraspecific variation in seed dormancy regulation in common waterhemp (Amaranthus tuberculatus)

Abstract Common waterhemp is an obligate outcrosser that has high genetic variability. However, under selection pressure, this weed shows population differentiation for adaptive traits. Intraspecific variation for herbicide resistance has been studied, but no studies have been conducted to determine the existence of variation for other adaptive traits that could influence weed management. The objective of this study was to examine the existence of different seed dormancy regulatory mechanisms in common waterhemp. Seed dormancy regulation, in response to different temperature and moisture regimes, was studied through germination experiments and proteome analysis using two common waterhemp biotypes (Ames and Everly) collected from agricultural fields in Iowa, and one biotype (Ohio) collected from a pristine area in Ohio. Without stratification, germination percentage among the different biotypes was 9, 29 and 88% for Ames, Everly, and Ohio respectively. The germination rate of seeds from Ames was dramatically increased after incubation at either 4 or 25 C under wet conditions, whereas germination of seeds from Everly was only increased at 25 C under wet conditions. The Ohio biotype showed no change in germination response to any of the incubation treatments. Germination studies indicated that the rate of seed dormancy alleviation differed between biotypes. Seed protein profiles obtained from the three biotypes differed in protein abundance, number, and type. A putative small heat-shock protein (sHSP) of 17.6 kDa and isoelectric point (pI) 6.1 increased whereas a putative glyceraldehyde-3-phosphate dehydrogenase (G3PDH) of 30.9 kDa and pI 6.4 decreased in abundance in the Ames biotype as seed dormancy was reduced in response to incubation at 4 C and wet conditions. These two proteins did not change in the Everly and Ohio biotypes, suggesting that these proteins changed their abundance in response to seed dormancy alleviation. The results of this study suggest that differences in seed dormancy levels between the biotypes were due to different physiological regulatory mechanisms. Nomenclature: Common waterhemp, Amaranthus tuberculatus (Moq.) J.D. Sauer
Sensory Feedback in Hand Prostheses: A Prospective Study of Everyday Use

Introduction Sensory feedback in hand prostheses is lacking but wished for. Many amputees experience a phantom hand map on their residual forearm. When the phantom hand map is touched, it is experienced as touch on the amputated hand. A non-invasive sensory feedback system, applicable to existing hand prostheses, can transfer somatotopical sensory information via phantom hand map. The aim was to evaluate how forearm amputees experienced a non-invasive sensory feedback system used in daily life over a 4-week period. Methods This longitudinal cohort study included seven forearm amputees. A non-invasive sensory feedback system was used over 4 weeks. For analysis, a mixed method was used, including quantitative tests (ACMC, proprioceptive pointing task, questionnaire) and interviews. A directed content analysis with predefined categories sensory feedback from the prosthesis, agency, body ownership, performance in activity, and suggestions for improvements was applied. Results The results from interviews showed that sensory feedback was experienced as a feeling of touch which contributed to an experience of completeness. However, the results from the questionnaire showed that the sense of agency and performance remained unchanged or deteriorated. The ability to feel and manipulate small objects was difficult and a stronger feedback was wished for. Phantom pain was alleviated in four out of five patients. Conclusion This is the first time a non-invasive sensory feedback system for hand prostheses was implemented in the home environment. The qualitative and quantitative results diverged. The sensory feedback was experienced as a feeling of touch which contributed to a feeling of completeness, linked to body ownership. The qualitative result was not verified in the quantitative measurements. Clinical Trial Registration Name: Evaluation of a Non-invasive Sensory Feedback System in Hand Prostheses. Date of registration: March 15, 2019. Date the first participant was enrolled: April 1, 2015. ClinicalTrials.gov Identifier: NCT03876405 ORCID ID: https://orcid.org/0000-0002-4140-7478.
Virtual Embodiment Using 180° Stereoscopic Video

One of the most exciting possibilities of virtual reality is inducing in participants the illusion of owning a virtual body. This has become an established methodological paradigm allowing the study of the psychological and neural correlates of various scenarios that are impossible in the real world, such as gender or age switching. Thus far, full-body ownership illusions have been implemented by using real-time body tracking and avatars based on computer-generated imagery (CGI). We propose an alternative technique to induce perceived ownership over a (photorealistic) virtual body using 180° stereoscopic video, synchronous touch, and narration. We describe the technical components of our novel technique and an example implementation as part of a science–art project that enables participants to experience virtual bodies of different ages, and present the results of an experimental evaluation study based on this experience. Consistent with previous virtual embodiment studies using CGI-based techniques, we found that participants accept a photorealistic virtual body as their own irrespective of its appearance as indicated by similar ratings of the strength of body ownership over a virtual body of a child versus an adult. We further show that our novel technique can alter participants’ cognition in accordance with the characteristics of their virtual body. Specifically, young adult participants who were embodied in the virtual body of a child significantly overestimated the duration of the virtual reality experience compared to a control group who was embodied in a virtual body of their own age. This finding corresponds to chronological age differences in time estimations and extends previous research on virtual child embodiment. Overall, these findings provide initial evidence for the potential of our novel technique to create photorealistic embodiment experiences with comparable psychological effects as have been found using CGI-based techniques while reducing the costs and technical complexity in the production and application of virtual body ownership illusions.
Serotonergic Modulation of Sensory Neuron Activity and Behavior in Apteronotus albifrons

Organisms must constantly adapt to changes in their environment to survive. It is thought that neuromodulators such as serotonin enable sensory neurons to better process input encountered during different behavioral contexts. Here, we investigated how serotonergic innervation affects neural and behavioral responses to behaviorally relevant envelope stimuli in the weakly electric fish species Apteronotus albifrons. Under baseline conditions, we found that exogenous serotonin application within the electrosensory lateral line lobe increased sensory neuron excitability, thereby promoting burst firing. We found that serotonin enhanced the responses to envelope stimuli of pyramidal cells within the lateral segment of the electrosensory lateral line lobe (ELL) by increasing sensitivity, with the increase more pronounced for stimuli with higher temporal frequencies (i.e., >0.2 Hz). Such increases in neural sensitivity were due to increased burst firing. At the organismal level, bilateral serotonin application within the ELL lateral segment enhanced behavioral responses to sensory input through increases in sensitivity. Similar to what was observed for neural responses, increases in behavioral sensitivity were more pronounced for higher (i.e., >0.2 Hz) temporal frequencies. Surprisingly, a comparison between our results and previous ones obtained in the closely related species A. leptorhynchus revealed that, while serotonin application gave rise to similar effects on neural excitability and responses to sensory input, serotonin application also gave rise to marked differences in behavior. Specifically, behavioral responses in A. leptorhynchus were increased primarily for lower (i.e., ≤0.2 Hz) rather than for higher temporal frequencies. Thus, our results strongly suggest that there are marked differences in how sensory neural responses are processed downstream to give rise to behavior across both species. This is even though previous results have shown that the behavioral responses of both species to envelope stimuli were identical when serotonin is not applied.