Miracle-dz/UniFAR-FTUs huggingface dataset:
Infant Mortality among Twins from the Pelotas 2004 and 2015 Birth Cohorts

Objective: To describe the prevalence of multiple pregnancies and compare firstand second-born twins to each other and to singletons, in terms of infant mortality. Methods: The 2004 and 2015 Pelotas Birth Cohorts are population-based studies conducted in Pelotas, South Brazil. A monitoring system was assembled to detect all deaths of cohort participants in the first year of life. Infant Mortality Rate (IMR):1000 live births (LB) and its components (neonatal and post-neonatal mortality rates) were calculated. Results: Among 4,187 pregnancies in 2004 and 4,220 in 2015, respectively, 42 (1.0%) and 56 (1.3%) J Pediatr Perinatol Child Health 2022; 6 (1): 115-128 DOI: 10.26502/jppch.74050095 Journal of Pediatrics, Perinatology and Child Health 116 were multiple. Eighty-four twins were born alive in 2004 and 111 in 2015. The majority of twin pregnancies failed to reach 37 weeks (61.9% in 2004 and 82.2% in 2015). Prevalence of twin births < 34 weeks of gestation more than doubled from 2004 (19.0%) to 2015 (42.1%) (p=0.03). In the 2004 cohort, there were 79 infant deaths, three of which were twins, and in the 2015 cohort, among the 57 deaths, five were of twins. In the 2004 cohort there was no difference in IMR between twins and singletons. In the 2015 cohort, IMR in first-born twins was similar to that of singletons, whereas among second-born twins, the IMR was six times higher than in singletons (75.4:1,000 LB versus 12.5:1000 LB). Conclusion: While improvements in medical care may have led to improved survival among infants born at less than 34 weeks, these infants are still at increased risk of dying before reaching one year of age.
Recognition of the Mental Workloads of Pilots in the Cockpit Using EEG Signals

The commercial flightdeck is a naturally multi-tasking work environment, one in which interruptions are frequent come in various forms, contributing in many cases to aviation incident reports. Automatic characterization of pilots’ workloads is essential to preventing these kind of incidents. In addition, minimizing the physiological sensor network as much as possible remains both a challenge and a requirement. Electroencephalogram (EEG) signals have shown high correlations with specific cognitive and mental states, such as workload. However, there is not enough evidence in the literature to validate how well models generalize in cases of new subjects performing tasks with workloads similar to the ones included during the model’s training. In this paper, we propose a convolutional neural network to classify EEG features across different mental workloads in a continuous performance task test that partly measures working memory and working memory capacity. Our model is valid at the general population level and it is able to transfer task learning to pilot mental workload recognition in a simulated operational environment.
Nurses’ Experiences of Caring for Long-Term Care Residents With Dementia During the COVID-19 Pandemic

The COVID-19 pandemic has had a negative impact on older persons who reside in long-term care settings, especially residents living with dementia. The physical and psychological burden of the current pandemic has also been felt by frontline caring staff including nurses caring for persons living with dementia. The aim of the study was to explore the experiences of nurses while caring for residents with dementia who resided in long-term dementia care units during the COVID-19 pandemic. Nine Maltese nurses working in dementia care units were interviewed during the month of February 2021. Following analysis of the transcripts, three themes were identified; ‘living the challenges of the pandemic’, ‘passing through a roller coaster of emotions’ and ‘building on personal and organisational resilience’. The participants lived through several challenges which in turn generated both positive and negative emotions. Moving forward through this period mostly relied on their coping strategies, how they negotiated infection control measures with the residents’ quality of life and how their organisation was able to provide quality dementia care pre-COVID-19. The study indicated how personal and organisational resilience could have influenced the participants’ experience of the pandemic and helped nursing staff in developing new ways of working.
The Effectiveness of Semantic Mapping Strategy to Improve Students' Writing Skill on Recount Text in Language Dormitory

Semantic Mapping is a simple strategy used by students by clustering words starting with determining the main idea according to the theme they will tell and supported by words related to the main idea. this study aims to (1) The influence of semantic mapping strategy on students' ability to write recount text (2) to test the effectiveness of the semantic mapping strategy of students' ability to write recount text. The method used in this research is a Quasi-Experimental method with a Non-equivalent design. Data obtained through tests and documentation. The sample of this research was 15 students of Elementary. based on the results of the pre-test and post-test, students' ability in writing recount texts increased by 38, which is the difference between the control class' post-test average score of 48 and the experimental class's post-test average score of 86. Furthermore, based on the statistical calculation of 0.05, the value of Sig. < 0.05 (0.045 < 0.05), means that the use of the Semantic Mapping strategy is effective in improving the ability to write recount text.
βIII-Tubulin Structural Domains Regulate Mitochondrial Network Architecture in an Isotype-Specific Manner

βIII-tubulin is a neuronal microtubule protein that is aberrantly expressed in epithelial cancers. The microtubule network is implicated in regulating the architecture and dynamics of the mitochondrial network, although the isotype-specific role for β-tubulin proteins that constitute this microtubule network remains unclear. High-resolution electron microscopy revealed that manipulation of βIII-tubulin expression levels impacts the volume and shape of mitochondria. Analysis of the structural domains of the protein identifies that the C-terminal tail of βIII-tubulin, which distinguishes this protein from other β-tubulin isotypes, significantly contributes to the isotype-specific effects of βIII-tubulin on mitochondrial architecture. Mass spectrometry analysis of protein–protein interactions with β-tubulin isotypes identifies that βIII-tubulin specifically interacts with regulators of mitochondrial dynamics that may mediate these functional effects. Advanced quantitative dynamic lattice light sheet imaging of the mitochondrial network reveals that βIII-tubulin promotes a more dynamic and extended reticular mitochondrial network, and regulates mitochondrial volume. A regulatory role for the βIII-tubulin C-terminal tail in mitochondrial network dynamics and architecture has widespread implications for the maintenance of mitochondrial homeostasis in health and disease.
Effect of Sowing Dates on Yield Attributes, Yield and Economics of Linseed (Linum usitatissimum L.) Varieties

A field experiment was conducted during the rabi season of 2020-2021 at Agronomy farm, College of Agriculture, Nagpur to study the effect of sowing dates on yield attributes, yield and economics of linseed varieties. The treatment comprised of four sowing dates, i.e., 43rd meteorological week (22nd October - 28th October), 44th MW (29th October - 4th November), 45th MW (5th November - 11th November) and 46th MW (12th November - 18th November) in main plots and three varieties i.e., PKV-NL-260, PKV-NL-97 and JLS-73 in sub-plots, replicated three times in a split plot design. Sowing dates as well as varieties significantly affect yield attributes, yield and economics of linseed. The result of the experiment showed significantly higher number of capsule plant-1 (52.89), number of seed capsule-1 (8.11), seed yield (9.13 quintal/hectare), biological yield (25.45 q ha-1) and harvest index (35.87%), gross monetary return (Rs. 44688 ha-1) and net monetary return (Rs. 23436 ha-1) with benefit cost ratio (2.10) were recorded when crop sown during 44th MW. The variety PKV-NL-260 recorded significantly higher number of capsule plant-1 (48.08), number of seed capsule-1 (8.25), seed yield (8.85 q ha-1), biological yield (24.92 q ha-1) and harvest index (35.52%), gross monetary return (Rs. 43478 ha-1) and net monetary return (Rs. 22226 ha-1) with benefit cost ratio (2.04). The sowing date on 44th MW along with variety PKV-NL-260 was found significantly higher seed yield (9.95 q ha-1), gross monetary return (Rs. 48225 ha-1) and net monetary return (Rs. 26973 ha-1). Linseed crop sown during 44th MW along with variety PKV-NL-260 performed better than variety PKV-NL-97 and JLS-73.
Manipulating the Level of Sensorimotor Stimulation during LI-rTMS Can Improve Visual Circuit Reorganisation in Adult Ephrin-A2A5-/- Mice

Repetitive transcranial magnetic stimulation (rTMS) is a non-invasive brain stimulation technique that has the potential to treat a variety of neurologic and psychiatric disorders. The extent of rTMS-induced neuroplasticity may be dependent on a subject’s brain state at the time of stimulation. Chronic low intensity rTMS (LI-rTMS) has previously been shown to induce beneficial structural and functional reorganisation within the abnormal visual circuits of ephrin-A2A5-/- mice in ambient lighting. Here, we administered chronic LI-rTMS in adult ephrin-A2A5-/- mice either in a dark environment or concurrently with voluntary locomotion. One day after the last stimulation session, optokinetic responses were assessed and fluorescent tracers were injected to map corticotectal and geniculocortical projections. We found that LI-rTMS in either treatment condition refined the geniculocortical map. Corticotectal projections were improved in locomotion+LI-rTMS subjects, but not in dark + LI-rTMS and sham groups. Visuomotor behaviour was not improved in any condition. Our results suggest that the beneficial reorganisation of abnormal visual circuits by rTMS can be significantly influenced by simultaneous, ambient visual input and is enhanced by concomitant physical exercise. Furthermore, the observed pathway-specific effects suggest that regional molecular changes and/or the relative proximity of terminals to the induced electric fields influence the outcomes of LI-rTMS on abnormal circuitry.
Development of physics e-module based on integrated project-based learning model with Ethno-STEM approach on smartphones for senior high school students

Standard competency of graduate students of class XI in Physics learning is considered not optimal. One of the contributing factors is the unavailability of the Physics E-Module, which contains model steps and is integrated with a learning approach in order to direct students in active learning. This study aims to produce a Physics E-Module based on an integrated project-based learning model with an Ethno-STEM approach on smartphones for class XI high school students with valid, practical, and effective criteria. This is development research using the Plomp development model consisting of three stages: Preliminary Research, Development or Prototyping Phase, and Assessment Phase. The instruments used in this research include three questionnaires for preliminary study, validity and practicality, attitude observation sheets, written test sheets, and skills assessment sheets. The result obtained was a Physics E-Module based on an integrated project-based learning model with the Ethno-STEM approach on smartphones for class XI high school students who meet valid, practical, and effective criteria.
Sleep Quality, Mental Health and Learning among High School Students after Reopening Schools during the COVID-19 Pandemic: Results of a Cross-Sectional Online Survey

We aimed to assess whether high school students’ sleep quality, mental health and learning changed during the COVID-19 pandemic as adolescents transitioned from learning online back to studying in person. We conducted an anonymous online cross-sectional survey study at three competitive high schools in Vilnius, Lithuania, after they were reopened. Students provided subjective views on their study quality, their health as well as daily life while studying either virtually or in person and completed the Beck depression inventory (BDI), the Generalized anxiety scale-7 (GAD-7) and the Pittsburgh sleep quality index (PSQI). Among 628 (70.4% female) respondents, 268 (42.7%), 342 (54.5%) and 398 (63.4%) are suspected to have depression, an anxiety disorder or poor sleep, respectively. Students reported better study quality (Z = −12.435, p < 0.001) and physical health (Z = −9.176, p < 0.001), but worse sleep quality (Z = −19.489, p < 0.001), shorter sleep duration (Z = −19.509, p < 0.001) and worse self-reported mental health (Z = −2.220, p < 0.05) while learning in person. However, higher scores of in-person study quality and physical health were associated with lower depression and anxiety levels as well as better sleep. Our study suggests that the reopening of schools may exacerbate sleep and mental health-related issues among high school students but also be beneficial for their academic development and levels of physical activity.
Cost-Effectiveness of Screening Algorithms for Familial Hypercholesterolaemia in Primary Care

Although familial hypercholesterolemia (FH) screening within primary care is considered cost-effective, which screening approach is cost-effective has not been established. This study determines the cost-effectiveness of six case-finding strategies for screening of electronic health records to identify index patients who have genetically confirmed monogenic FH in English primary care. A decision tree was constructed to represent pathways of care for each approach (FH Case Identification Tool (FAMCAT) versions 1 and 2, cholesterol screening, Dutch Lipid Clinic Network (DLCN), Simon Broome criteria, no active screening). Clinical effectiveness was measured as the number of monogenic FH cases identified. Healthcare costs for each algorithm were evaluated from an NHS England perspective over a 12 week time horizon. The primary outcome was the incremental cost per additional monogenic FH case identified (ICER). FAMCAT2 was found to dominate (cheaper and more effective) cholesterol and FAMCAT1 algorithms, and extendedly dominate DLCN. The ICER for FAMCAT2 vs. no active screening was 8111 GBP (95% CI: 4088 to 14,865), and for Simon Broome vs. FAMCAT2 was 74,059 GBP (95% CI: −1,113,172 to 1,697,142). Simon Broome found the largest number of FH cases yet required 102 genetic tests to identify one FH patient. FAMCAT2 identified fewer, but only required 23 genetic tests.
Petrological implications of element redistribution during metamorphism: insights from meta-granite of the South Delhi Fold Belt, Rajasthan, India

Abstract Meta-granites of the South Delhi Fold Belt, northwestern India, contain spectacular reaction textures formed during the metamorphic replacement of primary minerals. Textural relationships imply that amphibole was replaced sequentially in two stages. Epidote + titanite + quartz symplectite formed syn-tectonically on amphibole grain boundaries/fractures, followed by post-deformational growth of euhedral garnet overprinting amphibole grains. Besides occurring as symplectite grown during deformation, titanite in this rock also developed as a post-tectonic corona around magnetite. Parent magnetite contains exsolutions of ilmenite and/or ultrafine lamellae of Ti-rich oxide (Ti-oxd). Textures involving coronal titanite suggest their formation through a magnetite + ilmenite(/Ti-oxd) + plagioclase → titanite reaction. Compositional attributes and the calculation of the gain versus loss of components during the reaction suggest that the Mn2+ for garnet (XSpss = 0.23–0.29) that grew replacing amphibole was supplied by ilmenite (Mn2+ is 0.118–0.128 apfu) as it disintegrated to form coronal titanite. The redistribution of components between the metamorphic reaction sites connects the texturally unrelated domains and suggests that these zones were in chemical equilibrium during metamorphism. We estimated the P–T conditions of metamorphism for these post-tectonic assemblages as ∼650–700 °C from pseudosection modelling and conventional thermometry. Zircon data from this study suggest that the granitic rock crystallized at 988.8 ± 8.8 Ma. We propose that the metamorphic phases replaced the primary minerals during the mid Neoproterozoic tectonic activity reported from this terrane. The syn-tectonic symplectitic assemblage formed as the temperature increased during prograde metamorphism, and the post-tectonic minerals developed at peak conditions following the cessation of deformation.
E-Cigarette Aerosols Promote Oral S. aureus Colonization by Delaying an Immune Response and Bacterial Clearing

E-cigarette (e-cig) vapor has been shown to play a pathological role in oral health and alter the oral microbiota, providing growth advantages for opportunistic pathogens. Enrichment of Staphylococcus aureus, a commensal resident in the oral cavity, correlates with the progression of periodontal disease, suggesting a role as an opportunistic pathogen. Environmental conditions, such as cigarette smoke, are known to increase S. aureus virulence, yet the role of S. aureus in periodontitis and oral preneoplasia is unknown. We exposed oral epithelial cells to e-cig aerosols and showed a dose-dependent cell viability reduction, regardless of nicotine content, in a possible attempt to repair DNA damage, as measured by pH2AX. S. aureus attachment to oral epithelial cells and bacterial biofilm formation were enhanced upon e-cig exposure, indicating an increased capacity for oral colonization. Mechanistically, e-cig aerosol exposure resulted in an immunosuppression, as determined by a reduction in IL8, IL6, and IL1β secretion by oral epithelial cells during co-culture with S. aureus. Consistent with this, e-cig vape reduced the oral epithelial cell clearance of S. aureus. Furthermore, we observed an increased expression of the inflammatory regulator COX2. This work suggests that e-cigs promote S. aureus colonization and modulate the oral inflammatory response, possibly promoting oral periodontitis and preneoplasia.
Green perceived value and intention to purchase sustainable apparel among Gen Z: The moderated mediation of attitudes

ABSTRACT Gen Z consumers are the most lucrative segment concerning fashion products, including apparel and have showcased a willingness to shift towards more sustainable processes. This research explores the mediating role of positive attitude towards sustainable apparel with green perceived value and intention to purchase sustainable apparel amongst Gen Z. The paper also explores a moderated mediation model with materialistic values and consumer knowledge about sustainable apparel as moderators. A survey method was employed to collect data, and 308 undergraduate students from universities of Delhi – National Capital Region (NCR) were selected as respondents. The study results indicated a partial mediating role of positive attitude towards sustainable apparel and confirms the moderating role of materialistic values and consumer knowledge about sustainable apparel. Further, materialistic values and consumer knowledge were suggested as significant moderators in the model. The study also confirms a significant relationship among – green perceived value, positive attitude towards sustainable apparel, and intention to purchase sustainable apparel.
Headteachers in Catholic schools in England: contemporary challenges. A follow-up research study: part 2

This paper is a follow up to a previous article published online in this journal (Fincham; 2019) in which the writer describes the first phase of research into contemporary challenges facing headteachers in Catholic schools in England as expressed from the perspective of headteachers within one diocese. It was evident from the first phase that leaders in Catholic schools are subject not only to pragmatic concerns about funding and recruitment but also to both implied and overt challenges to Catholic identity and integrity, which are tested by pressures of social media, which have an impact upon the mental and emotional health of young people, and a pervasive secular mind-set, which impinges on faith practice in families and in the community. It was noted that the reduction in the number of priests in Catholic dioceses in England has also often left the school as the single focus of the Catholic community, which has implications for sustaining spiritual capital. The first phase of the investigation examined responses to an open question in which headteachers at a Catholic diocesan conference were invited to indicate their three most pressing challenges. The responses were subject to a process of Thematic Analysis (TA), as a result of which five pre-eminent issues were identified. The opportunity was also taken to investigate the extent to which spiritual capital was being renewed in Catholic schools. These ‘categories of discourse’ informed the face-to-face interviews that were conducted with five primary headteachers and four secondary headteachers in the second phase of the investigation. The data gathered enabled the researcher to ascribe meaning to headteachers’ unique experiences.
Synthesis of Ionizable Calix[4]arenes for Chelation of Selected Divalent Cations

Two sets of functionalised calix[4]arenes, either with a 1,3-crown ether bridge or with an open-chain oligo ether moiety in 1,3-position were prepared and further equipped with additional deprotonisable sulfonamide groups to establish chelating systems for selected cations Sr2+, Ba2+, and Pb2+ ions. To improve the complexation behaviour towards these cations, calix[4]arenes with oligo ether groups and modified crowns of different sizes were synthesized. Association constants were determined by UV/Vis titration in acetonitrile using the respective perchlorate salts and logK values between 3.2 and 8.0 were obtained. These findings were supported by the calculation of the binding energies exemplarily for selected complexes with Ba2+.
Applying for RAMP Using a Cohort Model: Overcoming Challenges

Although comprehensive school counseling programs are implemented widely across the country, school counselors face myriad barriers to implementation. As such, we conducted a multilevel, descriptive case study to examine a school counseling cohort preparing to apply for the American School Counselor Association’s Recognized ASCA Model Program (RAMP) over a 2-year period. Due to the significant amount of data collected during the research process, this is the second article of a two-part study. Results of this study highlight the process of school counselors overcoming barriers to comprehensive program implementation via prolonged professional development and include the following themes: (a) overcoming a lack of training and knowledge on comprehensive school counseling programs and (b) advocating to overcome systemic barriers. We address considerations for counselor educators, school counseling professionals, and counseling organizations/associations.