Miracle-dz/UniFAR-FTUs huggingface dataset:
Vaccine-induced protection from homologous Tier 2 simian-human immunodeficiency virus challenge in nonhuman primates

Passive administration of HIV neutralizing antibodies (nAbs) can protect macaques from hard-to-neutralize (Tier 2) chimeric simian-human immunodeficiency virus (SHIV) challenge. However, conditions for nAb-mediated protection following vaccination have not been established. Here, we selected groups of 6 rhesus macaques with either high or low serum nAb titers from a total of 78 animals immunized with recombinant native-like (SOSIP) Env trimers from the BG505 HIV isolate. Repeat intrarectal challenge with homologous Tier 2 SHIVBG505 led to rapid infection in unimmunized and low-titer animals. In contrast, high-titer animals demonstrated protection that was gradually lost as nAb titers waned over weeks to months. From these results, we determined that an autologous serum ID50 nAb titer of ~1:500 was required to afford over 90% protection from medium-dose SHIV infection. We further identified autologous nAb titers, but not ADCC or T cell activity, as strong correlates of protection. These results provide proof-of-concept that Env protein-based vaccination strategies can protect against hard-to-neutralize SHIV challenge in rhesus macaques by inducing Tier 2 nAbs, provided appropriate neutralizing titers can be reached and maintained.
The Relationship Between Subclinical Ketosis and Ruminal Dysfunction in Dairy Cows

Abstract Ketosis is still an important problem which must be solved in dairy herds. Early precise diagnosis and proper evaluation of the cause of the disease is essential for good management of ketosis on dairy farms. The aim of our work was to analyse the occurrence of rumen dysfunction in connection with subclinical ketosis in dairy herds and to evaluate the relationships between beta-hydroxybutyrate (BHB) concentration in blood and metabolic parameters in blood, urine and rumen fluid. We analysed the results of metabolic profile tests performed in dairy cattle herds from 1,338 cows. The concentration of BHB significantly correlated with glucose, NEFA (nonesterified fatty acids), bilirubin, AST (aspartate aminotransferase), GGT (γ-glutamyl transferase), urea, magnesium and calcium in blood serum and with following parameters of rumen fluid – acetate, propionate, butyrate, acetate/propionate and infusoria. Significant but weak correlations were found between BHB and urine parameters (pH, specific gravity, potassium, magnesium, chloride). Subclinical ruminal acidosis was found in 23.1% and 16.7% of dairy cows with light (BHB 1.2–2 mmol/L) and more severe subclinical ketosis (BHB >2 mmol/L) and simple ruminal indigestion in 16.7% and 30%, respectively. On the basis of performed analysis we can conclude that rumen dysfunction is an important factor for the development of ketosis. Veterinary practitioners should suggest checking the feeding management in their diagnostic work with the aim to distinguish primary and secondary ketosis. Only complex and precise diagnostic work allows applying correct and successful therapy not only for individual animals but also for herd health management.
Production of Green Barley Sprouts on Rice Straw in the Presence of Microbial Inoculants and Elevated CO2 as an Unconventional Dual Bio-Food and Fodders

THE AIM of this investigation is to evaluate the nutritional quality and productivity of green barley sprouts and spent sprouts (roots and basal medium) cultivated on rice straw rather than using a conventional hydroponic system. To optimize the resulting products, barley was cultivated under a range of CO2 concentrations and in the presence of up to three different microbial inoculants. Barley sprouts both treated with 800ppm CO2 and grown on rice straw in the presence of a consortium of Azotobacter chroococcum, Bacillus megaterium and Pseudomonas fluorescens showed significantly greatest shoot length (16.4 and 15.33cm), shoot fresh weight (1315.03 and 1217.95g/m2) and dry weight (185.11 and 171.45g/m2) than sprouts subjected to the other treatments when harvested at the first and second cuts, respectively, beside the highest significant protein (21.79%) and lipid (2.14%) levels than sprouts subjected to the other treatments when harvested at the first cut. Spent sprouts subjected to the same treatment showed significantly highest protein (8.95%), and lipid (1.98%) levels, significantly lowest crude fiber (21.93%) and a lowest C/N ratio (31.8). The highest significant spent sprout yield (3302.1 g/m2) was obtained when sprouts were grown in the absence of inoculants and under ambient air conditions. This study demonstrates the possibility of increasing the productivity and nutritive value of barley sprouts by cultivating sprouts on rice straw via different microbial inoculants in combination with elevated CO2. The sprouts produced using this unconventional cultivation method was termed dual bio-barley fodder.
The Effects of Earnings Management, Free Cash Flow and Industry on Firm Performance: Empirical Evidence from Shariah-Compliant Companies in Malaysia

This study examined the relationship between Shariah-compliant firms' market performance with earnings management, free cash flow and industry. In this analysis, data from 2009 to 2011 were used to assess the post-financial crisis impact in 2008 before the 2012 Malaysian Code on Corporate Governance was adopted. This research duplicated the method used by Roychowdhury to assess the companies that are accused of engaging in the selling of products at an inflated price and that have excessive discretionary spending which is the proxy for earnings management. Free cash flow was calculated by deducting capital expenditure from cash flow operations. Although, industry was denoted as number 1 to 9 based on the Bursa Malaysia (BM) type of industry. Linear regression was used to assess the effect of earnings management, free cash flow and industry on the output of shariah-compliant companies in Malaysia. The results showed that Shariahcompliant companies have been able to improve their performance through free cash flow and earnings management practices. Free cash flow was found to increase linearly with firm performance which contradicts the previous result. The type of industry in which a firm operates often plays an important role in the success of the business. This research, however, could not classify the industry that outperforms other industries as the mean comparison was negligible. Such results provided no clear proof that sharia-compliant companies would comply with Shariah laws to prevent 'gharar' (uncertainties) in business practices.
Unmasking Antarctic mollusc lineages: novel evidence from philinoid snails (Gastropoda: Cephalaspidea)

Since its introduction, the genus Philine has epitomized numerous mollusc snails with strong morphological convergence. Recently, a molecular analysis including a wide taxon sampling split this group into four non‐sister families. Although they are especially diverse in cold and deep waters, no comprehensive studies are available for the Antarctic counterparts. Here, our morpho‐anatomical and molecular data suggest major changes in the systematics of the group. From the eight known species, two are synonymized, Antarctophiline amoena with A. alata, and A. gouldi with A. gibba, and two are transferred to the genus Antarctophiline, namely A. apertissima comb.n. and A. falklandica comb.n. Two new species are described, A. easmithi sp.n. and A. amundseni sp.n. from different depths in the eastern Weddell Sea. The elusive P. antarctica from the Ross Sea was found in the Weddell Sea and Waegelea gen.n. is erected to place this species. Both phylogenetic and morphological data support the erection of Antarctophilinidae fam.n. to embrace most of the Philinoidea species described in the Southern Ocean. Only two species of Philinidae are found in Antarctic waters, Spiraphiline bathyalis gen. et sp.n. from bathyal depths in the Weddell Sea and S. kerguelensis comb.n. from the Kerguelen Islands. In light of the new data provided for all described species and the phylogenetic framework proposed herein, we briefly discuss the diversification and biogeographical patterns of Antarctic philinoid snails. Overall, antarctophilinid species seem to have restricted and grossly nonoverlapping distributions suggesting allopatric speciation connected possibly to geographical or bathymetric isolation.
Negative Affect Induces Rapid Learning of Counterfactual Representations: A Model-based Facial Expression Analysis Approach

Counterfactual emotions including regret and disappointment play a crucial role in how people make decisions. For example, people often behave such that their decisions minimize potential regret or disappointment and therefore maximize subjective pleasure. Importantly, functional accounts of emotion suggest that the experience and future expectation of counterfactual emotions should promote goal-oriented behavioral change. Although many studies find empirical support for such functional theories, the cognitive-emotional mechanisms through which counterfactual thinking facilitates changes in behavior remain unclear. Here, we leverage computational models of risky decision-making that extend regret and disappointment theory to experience-based tasks, which we use to determine how people learn counterfactual representations of their decisions across time. Further, we use computer-vision to detect positive and negative affect (valence) intensity from participants’ faces in response to feedback, which we use to determine how experienced emotion may influence cognitive mechanisms of learning, reward sensitivity, or exploration/exploitation—any of which could result in functional changes in behavior. Using hierarchical Bayesian modeling and Bayesian model comparison methods, we found that: (1) people learn to explicitly represent and subjectively weight counterfactual outcomes with increasing experience, and (2) people update their counterfactual expectations more rapidly as they experience increasingly intense negative affect. Our findings support functional accounts of regret and disappointment and demonstrate the potential for computational modeling and model-based facial expression analysis to enhance our understanding of cognition-emotion interactions.
ANALISIS PENGARUH PROFITABILITAS, STRUKTUR MODAL, KEPEMILIKAN MANAJERIAL DAN DEWAN KOMISARIS INDEPENDEN TERHADAP NILAI PERUSAHAAN

The effect of profitability, capital structure, managerial ownership and independent board of commissioners on the company's value both simultaneously and partially. The technique used in sampling uses a purposive sampling method because in sampling it uses certain criteria. The research was conducted in the period 2016-2018. The analytical method used is multiple linear regression with the SPSS 22 program. The results of the study show that there is simultaneously an influence between profitability, capital structure, managerial ownership and independent board of commissioners on company value and partial profitability which has no influence on firm value, while capital structure, managerial ownership and independent board of commissioner have a significant effect on the value of the company.
Hedyotis taishanensis (Rubiaceae): A new species from Guangdong, China

Hedyotis taishanensis is described as a new species from China. It is similar to H. acutangula, but obviously differs in unbranched herbal stems with slightly winged ridges, petiolated leaves, abaxially pubescent stipules, terminal pleiochasium inflorescence. The phylogenetic analysis from nuclear ITS and plastid petD sequences of 27 taxa revealed that H. taishanensis was an independent lineage but closely related to the clade including the sympatric species endemic to the Pearl River Delta, Guangdong, China. It was evaluated as Least Concern according to the IUCN Red List Categories and Criteria.
Relationship between auditor integrity and organizational commitment to fraud prevention

PurposeThe purpose of this research is to obtain empirical evidence about the impact of auditor’s integrity and organizational commitment to the prevention of fraud.Design/methodology/approachThis research was conducted using questionnaires distributed to all internal auditors who worked at East Java Representatives Office of Indonesia’s National Government Internal Auditor. One hundred and thirteen questionnaires were distributed, and fifty-seven questionnaires were received, and all have validity eligible to use in this research. The hypothesis of this research was tested using the partial least square analysis with WarpPLS version 6.0 software.FindingsThe result of this research found that auditor’s integrity and organizational commitment affect positively to fraud prevention.Originality/valueUsing government internal auditors, this study believed, brings a new insight into government internal auditor behavior.
Comparison of the effectiveness of three methods of cognitive-behavioral therapy (individual counseling, group counseling and parent education) on reduction of ADHD syndrome

The purpose of this study was to investigate and compare the effectiveness of various cognitive-behavioral therapies on reduction of ADHD syndrome. The research method was semi-experimental. The population of this study included all schoolchildren aged 7 to 12 years old who received diagnosis of Attention Deficit Hyperactive Disorder (ADHD) and referred to psychiatric counseling clinics of Tehran city in November and December 2016. Out of this, 80 subjects were selected by cluster sampling method and available sampling. They were randomly assigned to three experimental and one control groups. The information was collected using Parental and Teacher’s ADHD Scale. To analyze the collected data, multivariate covariance test was used. The findings of this study showed that individual counseling has a significant effect on the reduction of ADHD syndrome in the parents scale and the teachers scale, and in all components of behavior in the class, participation and group collaboration, and attitude toward the power authorities, and reducing the syndrome of ADHD Also, the findings of this study showed that group counseling and parent education only affect the ADHD syndrome in the parent form and in the overall score of teacher form and also in the component of group collaboration and collaboration. Meanwhile, the findings of this study showed that there is no significant difference between the three methods of cognitive-behavioral therapy, namely, individual counseling, group counseling and parent education in reducing the syndrome of ADHD.
4′-(N-(Propan-1,2-dienyl)pyrrol-2-yl)-2,2′:6′,2″-terpyridine

A new pyrrole-substituted terpyridine derivative that possesses an allene moiety was obtained as an “unexpected” sole product during an attempt to alkylate the N-atom of pyrrole with propargyl bromide in order to obtain an alkyne-functionalized terpyridine.
Anchoring Bias of Behavior towards Legal Insider Trading Decision on Indicator 52-WeekHigh in Ho Chi Minh Stock Exchange

The paper considers the problem of bias anchoring behavior on legal insider trading decisions that occur in Ho Chi Minh City Stock Exchange. A major review of research done using monthly stock data that are consistently present in VN30 stock index for 10 years. The results in this study show that legal insider trading decisions (internal shareholders and related person's) are influenced by the behavior of the anchoring bias to the indicator 52-WeekHigh. The nearness of the stock price indicator of 52-WeekHigh encourages their tendency to commit sales more than purchasing decisions. It works in reverse, whensthe stock price areqfar from the indicator of 52WeekHigh, then the insider tend to purchase more shares than sales did. These conditions indicate that the insider performs a contrarian strategy to trade. While insider trading decisions made by the major shareholders are not affected by the indicator 52-WeekHigh. Those findings indicate that despite having access to insider information about the company is better than public investors in its decision-making is still susceptible to bias behavior. Keywords— legal insider trading, 52-WeekHigh, anchoring bias
The dark side of AI-powered service interactions: exploring the process of co-destruction from the customer perspective

ABSTRACT Artificial intelligence (AI)-powered chatbots are changing the nature of service interfaces from being human-driven to technology-dominant. As a result, customers are expected to resolve issues themselves before reaching out to customer service representatives, ultimately becoming a central element of service production as co-creators of value. However, AI-powered interactions can also fail, potentially leading to anger, confusion, and customer dissatisfaction. We draw on the value co-creation literature to investigate the process of co-destruction in AI-powered service interactions. We adopt an exploratory approach based on in-depth interviews with 27 customers who have interacted with AI-powered chatbots in customer service settings. We find five antecedents of failed interactions between customers and chatbots: authenticity issues, cognition challenges, affective issues, functionality issues, and integration conflicts. We observe that although customers do accept part of the responsibility for co-destruction, they largely attribute the problems they experience to resource misintegration by service providers. Our findings contribute a better understanding of value co-destruction in AI-powered service settings and provide a richer conceptualization of the link between customer resource loss, attributions of resource loss, and subsequent customer coping strategies. Our findings also offer service managers insights into how to avoid and mitigate value co-destruction in AI service settings.
Does Investor Attention Affect Stock Trading and Returns? Evidence from Publicly Listed Firms in China

Abstract Limited attention is an inevitable outcome of voluminous information. Investors facing a large number of stocks can only focus on a few and endeavor to have access to in-depth knowledge. Since the retrieved knowledge would affect investors’ decisions, investor attention becomes a factor in affecting stock returns and trading volumes. Through using 890,840 firm-week observations of Chinese listed firms between 2011 and 2018 as a sample, we document that investor attention, measured by abnormal Baidu search volume index (ASVI), is positively associated with contemporaneous stock returns but with a complete reversal in the subsequent period; and ASVI exhibits a positive link with trading volumes without a subsequent reversal, but its predictable ability becomes weaker in subsequent weeks. The effect of ASVI is pronounced for the ChiNext market and firms with higher level of financial transparency. We further find investor attention has been driven by five corporate events including earnings announcements, management forecasts, financial analysts following, mergers and acquisitions and dividend payout. This paper contributes to the theory of limited attention through using a direct measure of attention, providing evidence on its economic consequences in the Chinese stock market and exploring specific events that drive investor attention.
Electro-optic nanocomposites for high performance microwave photonic applications

Great interest is devoted to electro-optic (EO) polymers since they allow the fabrication of very high performance microwave photonic components, such as optical modulators and analog-to-digital converters, due to a much better velocity matching between microwave and optical signal as well as a higher EO coefficient than the very popular inorganic LiNbO3 material. This paper studies the influence of nanoparticle loading on optical properties of EO polymers. We are interested in the host-guest system. A proof of concept is investigated by using a polymer matrix in which we add Disperse Red One (DR1) chromophores. Our first investigations are realized with TiO2 nanoparticles, which are transparent at the telecommunications wavelength of 1.55 µm. The m-lines technique allows measuring the refractive index of the films. As expected, the refractive index increases when weight-weight percentage of DR1 to PMMA increases from 3.5 wt. % to 14 wt. %. The refractive index increase tends to saturate at high DR1 percentages, which suggests that DR1 aggregation occurs. By adding TiO2 nanoparticles, a further increase is observed that we discuss by considering both the refractive index of TiO2 and the possibility to decrease the DR1 aggregation.
Activation of L1 orthography in L2 word reading: Constraints from language and writing system

When reading in a second language, a reader’s first language may be involved. For word reading, the question is how and at what level: lexical, pre-lexical, or both. In three experiments, we employed an implicit reading task (color judgment) and an explicit reading task (word naming) to test whether a Chinese meaning equivalent character and its sub-character orthography are activated when first language (L1) Chinese speakers read second language (L2) English words. Because Chinese and English have different spoken and written forms, any cross language effects cannot arise from shared written and spoken forms. Importantly, the experiments provide a comparison with single language experiments within Chinese, which show cross-writing system activation when words are presented in alphabetic Pinyin, leading to activation of the corresponding character and also its sub-character (radical) components. In the present experiments, Chinese–English bilinguals first silently read or made a meaning judgment on an English word. Immediately following, they judged the color of a character (Experiments 1A and 1B) or named it (Experiment 2). Four conditions varied the relation between the character that is the meaning equivalent of the English word and the following character presented for naming or color judgment. The experiments provide evidence that the Chinese meaning equivalent character is activated during the reading of the L2 English. In contrast to the within-Chinese results, the activation of Chinese characters did not extend to the sub-character level. This pattern held for both implicit reading (color judgment) and explicit reading (naming) tasks, indicating that for unrelated languages with writing systems, L1 activation during L2 reading occurs for the specific orthographic L1 form (a single character), mediated by meaning. We conclude that differences in writing systems do not block cross-language co-activation, but that differences in languages limit co-activation to the lexical level.
KINDERGARTEN STUDENTS’ UNDERSTANDING OF THE QUALITY OF THEIR RELATIONSHIP WITH THEIR TEACHER

Teacher-child relationships in early childhood are increasingly considered as a prerequisite for children’s development. The Child Appraisal of the Relationship with the Teacher Scale (CARTS) (Vervoot, Doumen, & Verschueren, 2015) is a new multidimensional measure that evaluates the quality of teacher-child relationships from the children’s perspective. The purpose of this study was to confirm the factor structure of the Dutch version of CARTS in the Greek context, to describe the perceptions of young children about their relationship with their teachers and to examine whether child’s age, gender, and ethnicity contribute to this relationship. In total, 366 children (Mage= 5.4) from 36 kindergarten of Greece participated in this study. Results supported the construct validity of the CARTS scale. CFA implementation, consistent with attachment-based research revealed the three dimensions of the teacher-children relationships, Closeness, Dependency and Conflict. Supportive and warmth relationships were found. Children’s demographics characteristics affect the quality of teacher-child relationships. The results highlighted the importance of the dyadic relationships.