Miracle-dz/UniFAR-FTUs huggingface dataset:
Long-Term Analysis of Internal Exposure Dose-Reduction Effects by Food Regulation and Food Item Contribution to Dose after the Fukushima Daiichi Nuclear Power Plant Accident

Over 10 years have passed since the Fukushima Daiichi Nuclear Power Plant accident. This study verifies the efficacy of longitudinal regulation on internal exposure doses and analyzes food group contributions to radiation doses using accumulated monitoring test results. The committed effective doses in 10,000 virtual persons from fiscal year (FY) 2012 to 2021, with and without regulation, were estimated as products of radioactivity concentrations randomly sampled from the test results, food intake, and dose coefficient. The distributed values of food intake rather than a mean value in dose estimation were assumed to reflect food intake variations and avoid underestimation of internal exposure doses for high-intake consumers. Furthermore, the ingestion of radioactive cesium from the calculation was analyzed per food group. The 95th percentile of the internal exposure dose (the dose of a “representative person”) was less than 1 mSv/year in both FYs. The regulation effect was substantial in FY 2012, and no noticeable difference in radiation doses was found between the regulation and no regulation conditions after FY 2016. Internal exposure doses decreased until approximately FY 2016 and then remained constant. It was also shown that not only radioactivity concentration but also food intake is a major factor affecting cesium intake. In summary, it was confirmed that Japan had ensured food safety regarding radioactive materials.
BeEAM Conditioning including High-Dose Bendamustine before Autologous Stem Cell Transplantation Is Safe and Effective in Patients with Waldenstrom’s Macroglobulinemia

High-dose chemotherapy (HDCT) with autologous stem cell transplantation (ASCT) is an option to consolidate remission in Waldenstrom’s macroglobulinemia (WM), particularly in selected younger patients with chemosensitive disease. BEAM, consisting of BCNU, etoposide, cytarabine, and melphalan, is often used as a conditioning regimen. However, problems with BCNU, including pneumotoxicity, tolerance, and availability, necessitate the search for alternatives. In this pilot study, we investigated high-dose chemotherapy with BeEAM, in which BCNU is replaced with high-dose bendamustine as an alternative conditioning regimen in six subsequent patients with WM. Bendamustine treatment was well tolerated without unexpected toxicities. The overall response rate was 6/6 patients (2 very good partial responses (VGPR) and 4 PR). After a median follow-up of 72 months, two (33%) patients relapsed. Median progression-free and overall survivals were not reached, and no severe late-onset toxicities were observed so far. In this pilot study, BeEAM conditioning before ASCT seems feasible, safe, and effective in patients with WM.
Activation of AMPK Entails the Protective Effect of Royal Jelly against High-Fat-Diet-Induced Hyperglycemia, Hyperlipidemia, and Non-Alcoholic Fatty Liver Disease in Rats

This study examined the mechanism underlying the protective effect of royal jelly (RJ) against high-fat-diet (HFD)-mediated non-alcoholic liver disease (NAFLD) in rats. Adult male rats were divided into five groups (n = 8 each): control fed a standard diet, control + RJ (300 mg/kg), HFD, HFD + RJ (300 mg/kg), and HFD + RJ + CC (0.2 mg/kg). The treatment with RJ reduced weight gain, increased fat pads, and attenuated fasting hyperglycemia, hyperinsulinemia, and glucose tolerance in the HFD-fed rats. It also reduced the serum levels of liver function enzymes, interleukin 6 (IL-6), tumor necrosis factor-α (TNF-α), and leptin but significantly increased the serum levels of adiponectin. In addition, and with no effect on lipid excretion in stool, RJ significantly decreased the hepatic mRNA expression of SREBP1, serum, hepatic cholesterol, and triglycerides but increased hepatic mRNA levels of PPARα. Furthermore, RJ reduced the hepatic levels of TNF-α, IL-6, and malondialdehyde (MDA) in the livers of these rats. Of note, with no effect on the mRNA levels of AMPK, RJ stimulated the phosphorylation of AMPK and increased the levels of superoxide dismutase (SOD) and total glutathione (GSH) in the livers of the control and HFD-fed rats. In conclusion, RJ attenuates NAFLD via its antioxidant potential and adiponectin-independent activation of liver AMPK.
Linearized 1-DoF Dynamic Model of an Underwater Vehicle Using CFD

The development of a dynamic model for yaw while considering the hydrodynamic forces acting on an underwater vehicle is inevitable if its performance during a mission like underwater structure inspection is to be examined. However, the high cost of underwater testing makes it impractical to obtain a model that adequately characterizes the vehicle dynamics. Therefore, this work suggests employing computational fluid dynamics (CFD) approach to develop a yaw model of the vehicle. Drag coefficient in the dynamic model is obtained using CFD analysis. On the other hand, the data from the thrust curve is used to compute the thrust coefficient. The resulting transfer function model is validated with experimental data of the vehicle. The model synthesised using the proposed approach is discovered to agree with the experimental results.
Inference sensitivity for Poisson mixtures

SUMMARY Data presented as contingency tables and classified by qualitative or quantitative methods are usually analysed on the basis of a Poisson log linear model. We examine the effect of Poisson mixtures, especially as represented by the negative binomial distribution, on statistical inference. The main finding is that probabilities of rejection are increased, sometimes considerably. In the case of heterogeneous binary data, attention is also given to the problems of analysis implied by Poisson mixtures.
Stratosphere–Troposphere Exchange and Its Relation to Potential Vorticity Streamers and Cutoffs near the Extratropical Tropopause

Abstract Two distinct dynamical processes near the dynamical tropopause (2-PVU surface) and their relation are discussed in this study: stratosphere–troposphere exchange (STE) and the formation of distinct potential vorticity (PV) structures in the form of stratospheric and tropospheric streamers and cutoffs on isentropic surfaces. Two previously compiled climatologies based upon the 15-yr European Centre for Medium-Range Weather Forecasts Re-Analysis (ERA-15) dataset (from 1979 to 1993) are used to establish and quantify the link between STE and these PV structures. An event-based analysis reveals a strong relation between the two processes. For instance, on isentropes below 320 K, 30%–50% of the stratospheric streamers are associated with downward STE. In the reverse perspective, between 60% and 80% of all STE events between 290 and 350 K are found in the vicinity of at least one PV structure. On different isentropes, the averaged downward (STT) and upward (TST) mass fluxes associated with PV structures.
Effective differentiation of double negative thymocytes requires high fidelity replication of mitochondrial DNA in an age dependent manner

One of the most proliferative periods for T cells occurs during their development in the thymus. Increased DNA replication can result in increased DNA mutations in the nuclear genome, but also in mitochondrial genomes. A high frequency of mitochondrial DNA mutations can lead to abnormal mitochondrial function and have negative implications on human health. Furthermore, aging is accompanied by an increase in such mutations through oxidative damage and replication errors. Increased mitochondrial DNA mutations cause loss of mitochondrial protein function, and decrease energy production, substrates, and metabolites. Here we have evaluated the effect of increased mitochondrial DNA mutations on T cell development in the thymus. Using mice carrying a mutant mitochondrial DNA polymerase γ (PolG) that causes increased mitochondrial DNA mutations, we show that high fidelity replication of mitochondrial DNA is pivotal for proper T cell development. Reducing the fidelity of mitochondrial DNA replication results in a premature age-dependent reduction in the total number of CD4/CD8 double negative and double positive thymocytes. Analysis of mitochondrial density in thymocyte subpopulations suggests that this may be due to reduced proliferation in specific double negative stages. Taken together, this work suggests that T cell development is regulated by the ability of mitochondria to faithfully replicate their DNA.
Evolution of the Strengthening Effects of In Situ TiB Fibers in a Ti Composite with Various Levels of Thermal Processing

Thermal processing is a useful method for improving the strengthening effects of fibers used to reinforce metal matrix composites (MMCs), but the corresponding models have not been constructed. In this work, a Ti matrix composite (TMC) reinforced by in situ TiB fibers was prepared, then thermal processing was applied to it at different levels of deformation to align the TiB fibers along the loading direction. Changes in the microstructure of the matrix, the orientation and the aspect ratio of the TiB fibers during this process were investigated. It was found that the aspect ratio of TiB fibers decreased sharply after a large amount of deformation. The strengthening effect of TiB fibers in the composite was simulated by strengthening models of the fibers, and the simulated results were verified by the results of tensile tests. The modeled results show that the strengthening factor (C0) of the in situ TiB fibers improved from 0.125 in the as-cast composite to 0.520, 0.688 and 0.858 by the processes with deformation ratios of 0.39, 0.26 and 0.14, respectively. The results of the tensile tests showed that the measured values of C0 gradually deviated from the modeled ones with an increase in the ratio of deformation applied during processing, and the deviation could be interpreted with the strengthening models.
Salient pitch cues in the perception of contrastive focus

The distinction between contrastive and noncontrastive focus in English can be conveyed by the difference between a L+H* vs H* pitch accent [Pierrehumbert and Hirschberg, in Intentions in Communication, edited by Cohen et al. (MIT, Cambridge, MA, 1990)]. It is unclear, however, which acoustic properties of an F0 contour convey to a listener the occurrence of the contrastive L+H* rather than the noncontrastive H*. In these experiments, rise onset F0, peak F0, and slope were varied to see how they alone and together contribute to the contrast between a L+H* vs H* on the focused constituent. Listeners classified the stimuli as either contrastive or noncontrastive, with discourse context distinguishing the two interpretations. Peak height and slope traded in determining the category boundary between interpretations. Implications for the choice of primitives in intonational models and for compositional approaches to tune meaning are discussed. [Work supported by NIH. ]
The collective radio properties of symbiotic stars

Radio measurements of symbiotic stars are reported which extend the search for radio emission and provide multifrequency and multiepoch measurements of previously detected stars. The results show no evidence that there are time variations in excess of about 30 percent over a period of several years in the detected stars. The radio flux densities are correlated with brightness in the IR, especially at the longer IR wavelengths where dust emission dominates. It is confirmed that symbiotics with the latest red giant spectral types are the most luminous radio emitters. The D-types are the most radio-luminous. Virtually all detected stars with measurements at more than one frequency exhibit a positive spectral index, consistent with optically thick thermal bremsstrahlung. The binary separation for a number of radio-emitting symbiotics is estimated, and it is found that the distribution of inferred binary separations is dramatically different for IR D-types than for S-types. 37 refs.
Nuclear Epidermal Growth Factor Receptor Overexpression as a Survival Predictor in Oral Squamous Cell Carcinoma

The aim of this study was to determine, by immunohistochemical methods, the expression of nEGFR and markers of cell proliferation (Ki-67), cell cycle (mEGFR, p53, cyclin D1), and tumor stem cells (ABCG2) in 59 pathohistological samples of healthy oral mucosa, 50 oral premalignant changes (leukoplakia and erythroplakia), and 52 oral squamous cell carcinomas (OSCC). An increase in the expression of mEGFR and nEGFR was found with the development of the disease (p < 0.0001). In the group of patients with leukoplakia and erythroplakia, we found a positive correlation between nEGFR and Ki67, p53, cyclin D1, and mEGFR, whereas in the group of patients with OSCC, we found a positive correlation between nEGFR and Ki67, mEGFR (p < 0.05). Tumors without perineural (PNI) invasion had a higher expression of p53 protein than tumors with PNI (p = 0.02). Patients with OSCC and overexpression of nEGFR had shorter overall survival (p = 0.004). The results of this study suggest a potentially important independent role of nEGFR in oral carcinogenesis.
Synoptic-Scale Precursors to Significant Cold-Season Precipitation Events in Burlington, Vermont

Abstract Several classes of significant cold-season precipitation events occurring in Burlington, Vermont (KBTV), during the 33-yr period from 1963 to 1995, are studied with the objective of identifying large-scale circulation precursors to the more extreme events. Several physically interesting and unique features that correspond to 24-h totals of 25 to 50 mm of precipitation are found. Preferential southerly and more maritime surface geostrophic flow occur in the heavier cases, in association with a strong cyclone (anticyclone) to the west (east) of KBTV. The 1000–500-hPa positive thickness anomaly corresponds to a depth-mean virtual temperature anomaly of +10.5°C in the heavy events. Additionally, statistically significant negative thickness anomalies, responsible for triggering these significant precipitation events, can be traced westward to a position in the Pacific Ocean at least 6 days prior to the event. Significantly heavier precipitable water amounts and preferentially strong water vapor transp.
Are the Super-Star Clusters of NGC 1569 in a Poststarburst Phase?

We present spectroscopic observations in the near-ultraviolet, optical, and near-infrared of the super- star clusters (hereafter SSC A and SSC B) in NGC 1569. Previous studies have suggested that they are in a poststarburst phase. However, our data suggest a younger mean age and a significant age spread. The spectrum of SSC A shows the Wolf-Rayet (W-R) feature at 4686 Å, with a luminosity equivalent to 20-40 WNL stars. This qualifies NGC 1569 as a W-R galaxy. The small Balmer jump detected in both clusters also suggests strongly the presence of very massive (and therefore very young) stars. Evolutionary synthesis models are used to constrain the star formation scenario by explaining the spectral energy distribution, the Balmer jump, the equivalent width (EW) of the W-R bump, and the near-infrared Ca II triplet in absorption. No single-age stellar population fits all these constraints. We propose a two-burst model, with the younger burst having an age of 3 Myr (2 Myr for SSC B) and the older one having an age of 9 Myr (8 Myr for SSC B), to explain the simultaneous presence of hot massive stars and red supergiants. We speculate that sequential star formation is taking place in the SSCs of NGC 1569, with the younger burst probably located in the surroundings of and initiated as a consequence of the energetic stellar activity of the older central compact cluster. A deficit of ionized gas was found around the SSCs, which we ascribe to the strong stellar winds and supernova explosions of the older burst removing the gas from the vicinity of the clusters.
The Effect of the Talking Stick Cooperative Learning Model on Biology Learning Outcomes at SMA Negeri 1 Waingapu

This study aims to determine the effect of the Talking Stick Cooperative Learning Model on Biology Learning Outcomes at SMA Negeri 1 Waingapu. This type of research is a quasi-experimental design using a nonequivalent control group design with a quantitative approach. Sampling using purposive sampling. The population in this study were students of class XI MIPA in the odd semester of the 2022/2023 academic year. The sample of this study was 37 students of class XI MIPA 1 as the control class and 37 students of XI MIPA 5 as the experimental class. The results of the descriptive analysis obtained showed that the average pre-test and post-test scores for the experimental class were 61.76 <76.89. Meanwhile, the average value - average pre-test and post-test control class 58.81 <69.81. Testing the hypothesis using a paired sample t-test produces an Asymp value. Sig (2-tailed) 0.000 means the value is less than 0.05 (<0.05). It can be concluded that the talking stick cooperative learning model affects learning outcomes
RXTE detects 245 Hz X-ray pulsations from IGR J17511-305

RXTE PCA Bulge scans detected activity of what appeared to be a known source. However, based on the results presented below, and the report of a new INTEGRAL source IGR J17511-305 (Baldovin et al. ATEL #2196), the activity detected by RXTE is due to a new 245 Hz X-ray pulsar.
The Nuclear Region of NGC 1068: High-Accuracy Alignment of the Optical and Radio Emission

We present the results of a campaign to obtain an accurate registration of Hubble Space Telescope (HST) and MERLIN images of NGC 1068, the prototypical Seyfert 2 galaxy. The final registration is accurate to 100 mas. A strong anticorrelation between radio and optical emission is revealed; in particular, the radio jet lies on a region of relatively low optical emission and is surrounded by line-emitting clouds. A major exception is the brightest narrow-line region (NLR) knot, cloud B, which lies, at least in projection, along the radio jet. These results can be understood as due to the interaction between the jet and the surrounding medium: in this scenario, the outflowing plasma is sweeping and heating the interstellar gas. As a result of this interaction and compression, the line emission is highly enhanced along the edges of the radio jet. It therefore appears that the morphology of the NLR of NGC 1068 is dominated by the presence of a radio outflow, as already revealed by HST observations of several Seyfert galaxies with extended radio emission. The optical peak seen in the HST images is located at α = 02h42m40. ˢ711, δ = -00°00'47. ″81 (J2000, FK5), with an error of 80 mas. The hidden nucleus, as determined by HST imaging polarimetry, falls at α = 02h42m40. ˢ710, δ = -00°00'48. ″11 (J2000, FK5). It is offset toward the south (i.e., along the radio axis) with respect to the two southernmost radio components and, in particular, by 170 mas from the inverted spectrum radio component, S1. This does not rule out that S1 is indeed the radio core but suggests that the nucleus of NGC 1068 might be radio silent, or its emission absorbed at radio wavelengths also. There are several contributions to the final accuracy of the optical-to-radio registration. A significant decrease of the astrometric error budget has to wait for substantial improvements, like those expected from the radio-optical link in the forthcoming HIPPARCOS catalog.
Grevillea tesselata Olde (Proteaceae: Grevilleoideae: Hakeinae), a rare new species of uncertain affinity from the Avon Wheatbelt region of south-west Western Australia.

Grevillea tesselata Olde is described here as a new species from south-west Western Australia, known only from a small population in a fragmented roadside landscape, and previously recognised under the phrase name Grevillea sp. Trayning (W. Johnston WJ 071). Following the Flora of Australia, the new species keys to the Grevillea Acacioides Group which comprises only three species, G. endlicheriana Meisn. , G. acacioides C.A. Gardner ex McGill. and G. gordoniana C.A. Gardner. A binary assessment of 50 morphological characters presented here supports the view that G. acacioides and G. endlicheriana are sister species. A key to the new species is provided and its distribution updated. Grevillea tesselata has a Priority One Conservation Code according to the Western Australian Herbarium.
Design of flat-panel displays based on organic light-emitting devices

We provide a systematic and quantitative analysis of the design of flat-panel displays (FPDs) based on organic light-emitting devices (OLEDs). Key performance parameters are estimated for OLED-based displays; system issues, including addressing schemes and strategies required to achieve full-color displays, are treated quantitatively. Furthermore, addressing schemes for recently demonstrated, full-color high-resolution stacked OLED's are discussed. Our analysis shows that OLED technology is suitable for many FPD applications, and can provide performance superior to that achieved using alternative display technologies.
On the mechanism of recombination at oxide precipitates in silicon

Oxide precipitates are well known to degrade minority carrier lifetime in silicon, but the mechanism by which they act as recombination centres is not fully understood. We report minority carrier lifetime measurements on oxide precipitate-containing silicon which has been intentionally contaminated with iron. Analysis of the injection-dependence of lifetime demonstrates the same recombination centres exist in iron-contaminated and not intentionally contaminated samples, with the state density scaling with iron loss from the bulk. This shows that recombination activity arises from impurity atoms segregated to oxide precipitates and/or surrounding crystallographic defects.
Statistical analysis of the geometric de-eutrophication software-reliability model

A detailed statistical analysis of the Moranda geometric de-eutrophication software-reliability model, which appears to be a particular case of a class of general models with proportional failure rates, is given. Statistical inference on the unknown parameters is discussed. The distribution of the maximum-likelihood estimator of the main parameter provides exact confidence intervals and a novel reliability-growth test. Explicit estimators based on a least-squares method are proposed. The model is satisfactorily applied to real software error data. The geometric de-eutrophication model presents interesting theoretical and practical aspects. It is conceptually well founded and the parameters, which have useful practical interpretation, can be estimated by methods which provide prediction with good statistical properties. >
Comparison of Simulation and Measurements of Time-Domain Field-to-Line Coupling in Bounded wave Simulator

This paper presents an analysis of time-domain electromagnetic pulse coupling to single wire. A field-to-line coupling model was established. The simulation is performed using the uniform plane wave excitation defined by measured high-altitude nuclear electromagnetic pulse (HEMP) field signal, the induced currents of two load terminals are simulated. The validation measurement of single wire above the grounding plate is conducted in the bounded wave simulator. The frequency response of the actual coupled current signal monitoring system is considered in the data preprocessing. The comparison between simulation and measurement results show that the peak amplitude and waveform can coincide well.