Miracle-dz/UniFAR-FTUs huggingface dataset:
Antimicrobial efﬁcacy of eucalyptus oil and 1,8-cineole alone and in combination with chlorhexidine digluconate against microorganisms grown in planktonic and bioﬁlm cultures

Objectives : Effective disinfection and antisepsis is pivotal in preventing infections within the healthcare setting. Chlorhexidine digluconate (CHG) is a widely used disinfectant/antiseptic possessing broad-spectrum antimicrobial activity; however, its penetration into bacterial bioﬁlms and human skin is poor. The aim of this study was to investigate the antimicrobial efﬁcacy of crude eucalyptus oil (EO) and its main component 1,8-cineole (a recognized permeation enhancer), alone and in combination with CHG, against a panel of clinically relevant microorganisms grown in planktonic and bioﬁlm cultures. Methods : MICs and minimum bactericidal/fungicidal concentrations were determined for each microorganism grown in suspension and bioﬁlm using microbroth dilution and ATP bioluminescence, respectively. Chequerboard assays were used to determine synergistic, indifferent or antagonistic interactions between CHG and EO or 1,8-cineole. Results : Antimicrobial activity was demonstrated by CHG, EO and 1,8-cineole; however, CHG was signiﬁcantly more active against microorganisms in both planktonic and bioﬁlm modes of growth ( P < 0.05). Crude EO was signiﬁcantly more efﬁcacious against microorganisms grown in suspension compared with 1,8-cineole ( P < 0.05). Synergistic activity was demonstrated between CHG and both EO and 1,8-cineole against suspensions of Staphylococcus aureus , methicillin-resistant S. aureus (MRSA), Escherichia coli and Candida albicans , and bioﬁlm cultures of MRSA and Pseudomonas aeruginosa . Conclusions : In conclusion, CHG may be combined with either crude EO or its major component 1,8-cineole for enhanced, synergistic antimicrobial activity against a wide range of microorganisms in planktonic and bioﬁlm modes of growth; however, the superior antimicrobial efﬁcacy associated with crude EO alone, compared with 1,8-cineole, favours its combination with CHG. tissue microtitre bioﬁlm
Schönemann–Eisenstein–Dumas-Type Irreducibility Conditions that Use Arbitrarily Many Prime Numbers

The famous irreducibility criteria of Schönemann–Eisenstein and Dumas rely on information on the divisibility of the coefficients of a polynomial by a single prime number. In this paper, we will use some results and ideas of Dumas to provide several irreducibility criteria of Schönemann–Eisenstein–Dumas-type for polynomials with integer coefficients, criteria that are given by some divisibility conditions for their coefficients with respect to arbitrarily many prime numbers. A special attention will be paid to those irreducibility criteria that require information on the divisibility of the coefficients by two distinct prime numbers.
Investigating Cognitive demand of Higher-level Leaving Certificate Examination Pre- and Post-

In 2010 the phased introduction of the new Project Maths curriculum began in post-primary schools in Ireland. This new curriculum aimed to enable students to develop problem-solving skills by providing relevant, contextual applications of mathematics, while simultaneously increasing the levels of cognitive demand required of students. This research aims to investigate whether the levels of cognitive demand required to complete tasks in the Leaving Certificate Higher-level mathematics examinations changed as a result of the curriculum reform. The methodology of this research includes the systematic analysis of Leaving Certificate examination tasks, from 2007 to 2017, using an adaptation of the Stein and Smith (1998) task analysis framework. Using this framework, tasks were classified as being of high-level or low-level cognitive demand. Analysis of the data collected suggests that a statistically significant increase in the levels of high-cognitive demand tasks did occur following the curriculum reform. Our findings are discussed in relation to two recent studies that used different frameworks to examine the cognitive demand of tasks in post-primary mathematics.
RMHP_A_297846 987..995

Department of Epidemiology and Biostatistics, College of Medicine and Health Sciences, Wollo University, Dessie, Ethiopia Purpose: Coronavirus disease-2019 is an emerging disease that threatens the world. With the absence of successful treatment precipitated by the lack of health infrastructures in developing countries including Ethiopia, efforts to enhance the attitudes and practice of people are critical for managing the pandemic. Hence, this study aimed to assess the practice, attitude towards COVID-19, and divine belief among residents in Ethiopia. Patients and Methods: A community-based cross-sectional study combining qualitative design was conducted in August 2020. The qualitative design was employed to explore the respondents’ divine belief towards the COVID-19 pandemic. Chi-square analysis was computed to identify factors associated with practice against COVID-19 prevention measures. The calculated chi-square greater than the tabulated value at a degree of freedom ((row total-1) * (column total)) and P-value <0.05 were considered statistically significant. Results: In this study, a total of 508 respondents participated. The mean age of the participants was 38.4 ± 11.2 (SD) years. The overall practice of prevention measures and attitude towards COVID-19 was 53.3% (95% CI: 49.0–57.6%) and 49.6% (95% CI: 45.3–53.9%), respectively. Age, residency, educational status, monthly income of the household, having a child, and attitude towards COVID-19 were statistically significant predictors of COVID-19 prevention measures (P< 0.05). Conclusion: As the global threat of COVID-19 continues, it is critical to improving the respondents’ practice and attitude towards the precautionary measures, especially some religious followers.
Crossed Beam Reaction of 0{ 1 D) + D 2 ~ OD + D by Velocity Map Imaging: The Role of Excited States

The technique of velocity map imaging [A. T. J. B. Eppink, and D. H. Parker, Rev. Sci. Instrum. 68, 3477 (1997)] has been applied to the reaction oeD) + D 2 ~ OD + D under single collision conditions in crossed molecular beams at collision energies (Econ) of 2.8 and 5.5 kcal/mol. Images of the reactively scattered D atom product were recorded, yielding the full double differential cross sections (energy and angle) for the reaction. The observed D atom angular distribution is broad in the backward sphere and sharply peaked in the forward sphere, and the translational energy release and angular distributions are strongly coupled. There is an increase in scattering in the backward sphere with an increase in collision energy. Although the overall translational energy distributions do not change significantly with Ecoll we observe an increase in the contribution in the backscattering at the higher Ecoll· These observations are ascribed to the interplay of the ground state potential energy surface (lA') with excited states (I A", 2A') which can lead to different scattering mechanisms (insertion versus abstraction) as has been suggested recently in theoretical and experi~ental studies.
Overexpression of Activin (cid:1) C or Activin (cid:1) E in the Mouse Liver Inhibits Regenerative Deoxyribonucleic Acid Synthesis of Hepatic Cells

Activins are dimeric growth factors composed of (cid:1) -subunits, fourofwhichhavebeenisolatedsofar.Whereasactivin (cid:1) A and (cid:1) B are expressed in many tissues, the expression of activin (cid:1) C and (cid:1) E is confined to the liver. To date no biological role or activity has been assigned to activins formed from (cid:1) C or (cid:1) E subunits(activinCandE). BecauseactivinA( (cid:1) A (cid:1) A ),amongits various functions in other tissues, appears to be a negative regulator of liver growth, we hypothesized a similar role for activin C and E. Using a nonviral gene transfer system we specifically delivered genes encoding activin (cid:1) C , (cid:1) E , or (cid:1) A to the mouse liver. The mRNA analysis and reporter gene coexpression both indicated a reproducible temporal and spatial transgene expression pattern. The effects of activin overex- pression were studied in the context of a regenerative proliferation of hepatic cells, a result of the tissue damage associ- ated with the hydrodynamics based gene transfer procedure. Activin (cid:1) C , (cid:1) E , or (cid:1) A expression, all temporarily inhibited re- generative DNA synthesis of hepatocytes and nonparenchymal cells, though to
Parental Treatment Methods and their Relationship to Adolescents' Behaviors of Using Social Media Programs

The Using Internet and modern technologies greatly affected the lives of adolescents. Parents find it difficult to control them as required. The objective of this research is to find the relationship between the methods of parental treatment and the behavior of adolescent users of social media websites. There is a statistically significant inverse correlation between parental treatment methods and the behavior of adolescent users of social media websites. The correlation coefficient of parental treatment methods for fathers was 0.871** and for mothers was 0.752**. Therefore, there are differences in methods of parental treatment among parents in favor of mothers. There are statistically significant differences between the behavior of adolescent users of social media websites according to the gender and the age.
How to use the LBE package

In the context of genome-wide studies for which a large number of statistical tests are simultaneously performed, the False Discovery Rate (FDR) which is defined as the expected proportion of false discoveries [1] is one of the most used criterion for taking into account the multiple testing problem. In the framework of estimating procedures based on the marginal distribution of the pvalues without assumption on the conditional distribution related to the alternative hypothesis, estimators of the FDR rely on the formula introduced by Storey [4]:
Rural Romania within the Political Economy of the Golden Age

The research proposed here investigates the significant transformations of the Romanian countryside -- from communist-forced collectivization to a dramatic program of rural systematization, during the distinctive communist stage ruled by Nicolae Ceausescu, 1965-1989, the so-called golden age. Factor analysis revealed that Ceausescu, who evolved from a leader apparently committed to modernization and liberalization in 1965 to a regressive neo - Stalinist despot by 1989, was the moral author of some radical campaigns with negative consequences on agricultural practice and rural life. It can be concluded that rural Romania was profoundly changed by the communist rule and Soviet domination, agricultural policy functioning as the heavy artillery of the Communist Party against the Romanian peasants.
Sex-speci c Longitudinal Comparison of CES-D and PHQ-9 Depression Scales. A Concordance Analysis using data from the population-based Heinz Nixdorf Recall Study

Miriam Engel (  miriam.engel@uk-essen.de ) Institute for Medical Informatics, Biometry, and Epidemiology, University Hospital Essen https://orcid.org/0000-00030161-0858 Markus Peternel Centre for Urban Epidemiology, Institute for Medical Informatics, Biometry, and Epidemiology, University Hospital Essen, University of Duisburg-Essen, Germany Karl-Heinz Jöckel Institute for Medical Informatics, Biometry, and Epidemiology, University Hospital Essen, Germany Sara Schramm Insitute for Medical Informatics, Biometry, and Epidemiology, University Hospital Essen, Germany Uta Slomiany Institut for Medical Informatics, Biometry, and Epidemiology, University Hospial Essen, Germany Susanne Moebus Centre for Urban Epidemiology, Insitute for Medical Informatics, Biometry, and Epidemiology, University Hospital Essen, Germany
Edinburgh Explorer The response of leptin, interleukin-6 and fat oxidation to feeding in weight-losing patients with pancreatic cancer

At baseline, weight-losing pancreatic cancer patients ( n ¼ 7) had lower leptin ( P o 0.05) but higher cortisol, interleukin-6, resting energy expenditure and fat oxidation than healthy subjects ( n ¼ 6, P o 0.05). Over a 4 h feeding period, the areas under the curve for glucose, cortisol and interleukin-6 were greater ( P o 0.05), but less for leptin in the cancer group ( P o 0.05). Therefore, it would appear that low leptin concentrations, increased fat oxidation and insulin resistance are associated with increased concentrations of cortisol and interleukin-6 in weight-losing patients with pancreatic cancer. The discovery of leptin, an adipocyte-secreted protein that acts on the central nervous system to regulate body weight in animals (Pelleymounter et al 1995), has stimulated interest in the role of leptin in humans both in the obese and cachectic states. Evidence, in animals, suggests that circulating leptin concentrations regulate energy intake centrally (primarily through appetite) and expenditure (primarily through substrate oxidation) by a control feedback loop involving neuropeptide Y (Inui, 1999). Evidence, in humans, indicates that the major role of leptin appears in the adaptation to reduced energy intake and reduced body fat stores (Havel, 2002).
Mattinen, Miika and King, Peter J. and Khriachtchev, Leonid and Heikkilä, Mikko J. and Fleming, Ben and Rushworth, Simon and Mizohata, Kenichiro and Meinander, Kristoffer and Räisänen, Jyrki and Ritala,

Molybdenum forms a range of oxides with different stoichiometries and crystal structures, which lead to different properties and performance in diverse applications. Herein, crystalline molybdenum oxide thin films with controlled phase composition are deposited by atomic layer deposition. The MoO2(thd)2 and O3 as precursors enable well-controlled growth of uniform and conformal films at 200e275 C. The asdeposited films are rough and, in most cases, consist of a mixture of aand b-MoO3 as well as an unidentified suboxide MoOx (2.75 x 2.89) phase. The phase composition can be tuned by changing deposition conditions. The film stoichiometry is close to MoO3 and the films are relatively pure, the main impurity being hydrogen (2e7 at-%), with 1 at-% of carbon and nitrogen. Post-deposition annealing is studied in situ by high-temperature X-ray diffraction in air, O2, N2, and forming gas (10% H2/90% N2) atmospheres. Phase-pure films of MoO2 and a-MoO3 are obtained by annealing at 450 C in forming gas and O2, respectively. The ability to tailor the phase composition of MoOx films deposited by scalable atomic layer deposition method represents an important step towards various applications of molyb-
(cid:1) M s theory precision confronts (cid:13)avour anomalies

: Based on recent HQET sum rule and lattice calculations we present updated Standard Model predictions for the mass di(cid:11)erences of neutral B mesons: (cid:1) M SM s = (cid:16) 18 : 4 +0 : 7 (cid:0) 1 : 2 (cid:17) ps (cid:0) 1 and (cid:1) M SM d = (cid:16) 0 : 533 +0 : 022 (cid:0) 0 : 036 (cid:17) ps (cid:0) 1 and study their impact on new physics models that address the present hints of anomalous data in b ! s‘‘ transitions. We also examine future prospects of further reducing the theory uncertainties and discuss the implications of a 2025 scenario with (cid:1) M SM 2025 s = (18 : 4 (cid:6) 0 : 5) ps (cid:0) 1 . In particular, the latter yields upper bounds M Z 0 . 9 TeV and M S 3 . 30 TeV for the minimal Z 0 and S 3 lepto-quark explanations of the b ! s‘‘ anomalies, respectively.
In Transduced Cells, the U S 3 Protein Kinase of Herpes Simplex Virus 1 Precludes Activation and Induction of Apoptosis by Transfected Procaspase 3 (cid:1)

The U S 3 protein kinase of herpes simplex virus 1 blocks apoptosis induced by replication-incompetent virus mutants, proapoptotic members of the Bcl-2 family of proteins, and by a variety of other agents that act at the premitochondrial level in the proapoptotic cascade. To deﬁne the role of U S 3 in blocking apoptosis at the postmitochondrial level, we investigated the U S 3 protein kinase in transduced cells that were either transfected with a plasmid encoding procaspase 3 or superinfected with a proapoptotic mutant virus lacking the gene encoding the infected cell protein no. 4. (i) We show that U S 3 blocks the proteolytic cleavage that generates active caspase 3 from the transfected zymogen procaspase 3, concomitant with inhibition of apoptosis. (ii) Studies based on detection of ﬂuorescence emitted upon cleavage of a synthetic caspase 3 substrate showed that expression of the U S 3 kinase and appearance of the cleaved substrate were mutually exclusive. (iii) An afﬁnity-puriﬁed glutathione S -transferase (GST)-U S 3 fusion protein, but not the inactive GST-U S 3(K220N) protein, phosphorylated procaspase 3 in vitro. The studies published earlier on the effect of U S 3 on the upstream regulatory proteins and current studies suggest that the U S 3 protein kinase may act on several proteins in the proapoptotic
Genetic evaluation with a multiple lactation test day model for SCS

A multiple lactation model for test day data was applied to predict genetic merit for somatic cell scores of German Holsteins. This method has been implemented as official evaluation procedure in 1996. Application of this computationally demanding procedure has proven that a test day evaluation is feasible, even with large scale national datasets. Associations were desirable for EBV of SCS with EBV for some udder conformation traits and longevity evaluations, but undesirable for EBV for protein yield. Starting in August 1997 genetic evaluations for SCS will also be included in the total merit index for German Holsteins. ___________________________________________________________________________________
Effect of a 6-week Nordic hamstring intervention on athletic performance measures in rugby academy players: a randomised controlled trial

The lack of eccentric strength and its effect on injury has been thoroughly researched however the improvement of eccentric hamstring strength and its implications for athletic performance has been minimally investigated among a junior elite population. This parallel design randomised controlled trial aim was to assess a 6-week Nordic hamstring exercise (NHE) intervention and its effect on speed and jump performance. There were 50 young male rugby academy athletes allocated into two groups using non-blinded block randomisation: NHE training (n=25), or no NHE training (control) (n=25). Eccentric hamstring strength was assessed before and after the intervention using a NordBord. Sprint tests over 10m, 20m and 30m were assessed using Brower speed gates. Counter movement jump (CMJ) and squat jump (SJ) were assessed using a Kistler force plate. Confidence interval set at 95%. The NHE group showed significant 10% improvement in eccentric hamstring strength. Significant improvement in 10m, 20m and 30m was observed with significant differences from the control group in eccentric hamstring strength, 10m and 30m. The intervention group pre to post measure effect size for eccentric hamstring strength (Cohen’s d=0.64) was medium but the 10m (Cohen’s d=-0.02), 20m (Cohen’s d=-0.17) and 30m (Cohen’s d=-0.24) results were small. This NHE protocol is an appropriate short-term intervention to improve eccentric hamstring in junior elite athletes. Small improvements were made in sprint results with a greater improvement in 30m compared to 10m and 20m results. The improved eccentric strength could have architectural and neural adaptations to the hamstring that infers an improvement in speed.
ArticleBias Correction of the Ratio of Total Column CH4 to CO

The proxy method, using the ratio of total column CH4 to CO2 to reduce the effects of common biases, has been used to retrieve column-averaged dry-air mole fraction of CH4 from satellite data. The present study characterizes the remaining scattering effects in the CH4/CO2 ratio Remote Sens. 2020, 12, 3155 2 of 28 component of the Greenhouse gases Observing SATellite (GOSAT) retrieval and uses them for bias correction. The variation of bias between the GOSAT and Total Carbon Column Observing Network (TCCON) ratio component with GOSAT data-derived variables was investigated. Then, it was revealed that the variability of the bias could be reduced by using four variables for the bias correction—namely, airmass, 2 μm band radiance normalized with its noise level, the ratio between the partial column-averaged dry-air mole fraction of CH4 for the lower atmosphere and that for the upper atmosphere, and the difference in surface albedo between the CH4 and CO2 bands. The ratio of partial column CH4 reduced the dependence of bias on the cloud fraction and the difference between hemispheres. In addition to the reduction of bias (from 0.43% to 0%), the precision (standard deviation of the difference between GOSAT and TCCON) was reduced from 0.61% to 0.55% by the correction. The bias and its temporal variation were reduced for each site: the mean and standard deviation of the mean bias for individual seasons were within 0.2% for most of the sites.
IMMUNOMODULATORY EFFECT OF VOLATILE OIL FROM NIGELLA SATIVA ON THE ANIMALS LABORATORY (IN VIVO)

The study has employed an in vivo evaluation of the immune system effect of volatile and fixed oil in male albino mice at single dose concentrations (0.5 mg / kg) given injection for 7 days including measuring the IgM level and histopathlogical changes. At day 14, the animal was killed and the spleen was kept in 10% formalin for the preparation of histopathological sections, the serum was isolated from the blood for the biochemical tests. The statistical results showed the presence of significant changes on IgM between the groups of mice. Examination of the spleen tissue confirmed potential histopathological effects for volite oil as immunomodulatory in treated mice as widening of white pulp with a reduction of red pulp, so hyper plasia of lymphoid follicles with germinal center and platelet cytokines.
PRODUCTIVE AND REPRODUCTIVE PERFORMANCE OF SHEEP FED UREA TREATED CORN WITH COBS

Two trials with 27 pregnant Ossimi ewes and 15 from their successive born lambs were carried out to evaluate the effect of feeding urea treated corn with cobs (UCC) as 50% (T 2 ) or total replacement (T 3 ) of pelleted concentrate feed mixture (CFM) compared to the conventional diets (CFM) on its production and reproduction performance. Rice straw was offered separately from the concentrate. Evaluation criteria included DM intake and utilization, ruminal fermentation characteristics, milk yield, birth, weaning and marketing weight and feed efficiency. This study was conducted during the summer season (May through September 2003). In the first trial, 27 Ossimi, ewes beginning 45 days before expected day of lambing were assigned to the control, T 2 and T 3 diets. The milk was measured on day 14 post partum and once every week up to the 12 th week. The growth experimental periods were 137 day in duration using 15 weaned lambs. The selected lambs were allocated to the same three diets. In digestibility trial, 9 adult rams were allocated to the same three tested diets. In vivo digestibility, nutrients digestibility were different among diets. Feeding values (TDN) was greater for T 3 followed by control diet whereas the highest DCP was recorded for T 2 . Feeding UCC had no effect on ruminal parameters in terms of pH, NH 3 and total FVA`s across the sampling time except for NH 3 -N. The replacement of CFM by UCC resulted in insignificant higher (p≤0.05) lambs birth weight T 3 (3.44 kg) but lower milk yield T 3 (436 g /day). The lower birth weight of lambs of the control group (p ≤ 0.05) tended to grow faster and perform higher weaning as compared to the treated group. In the growth trail, feeding UCC diets reduced ADG by approximately 10% compared to control. The results indicated that DM, TDN and DCP needed to produce 1 kg gain were almost 5 to 10% better than the corresponding items from T 2 and T 3 . Replacement of CFM in pregnant and growing lamb’s rations with UCC would be cost effective as cost of UCC is 60% less than the cost of CFM.