Miracle-dz/UniFAR-FTUs huggingface dataset:
Rank‐structured approximation of some Cauchy matrices with sublinear complexity

In this article, we consider the rank‐structured approximation of one important type of Cauchy matrix. This approximation plays a key role in some structured matrix methods such as stable and efficient direct solvers and other algorithms for Toeplitz matrices and certain kernel matrices. Previous rank‐structured approximations (specifically hierarchically semiseparable, or HSS, approximations) for such a matrix of size n$$ n $$ cost at least O(n)$$ O(n) $$ complexity. Here, we show how to construct an HSS approximation with sublinear (specifically, O(log3n)$$ O\left({\log}^3n\right) $$ ) complexity. The main ideas include extensive computation reuse and an analytical far‐field compression strategy. Low‐rank compression at each hierarchical level is restricted to just a single off‐diagonal block row, and a resulting basis matrix is then reused for other off‐diagonal block rows as well as off‐diagonal block columns. The relationships among the off‐diagonal blocks are rigorously analyzed. The far‐field compression uses an analytical proxy point method where we optimize the choice of some parameters so as to obtain accurate low‐rank approximations. Both the basis reuse ideas and the resulting analytical hierarchical compression scheme can be generalized to some other kernel matrices and are useful for accelerating relevant rank‐structured approximations (though not subsequent operations like matrix‐vector multiplications).
Does the travel career pattern model work for repeat tourists?

Tourism researchers and practitioners have an interest in understanding tourists ’ travel patterns, and one of the most used models applied to reach this goal is the seminal Travel Career Pattern (TCP) model. However, repeat tourism is underexplored and in the present research, the authors provide an initial investigation of repeat tourists using the TCP model. Based on survey data from 500 international tourists in India the present research found that the TCP model is valuable for exploring repeat tourists ’ travel patterns and motives. Within the TCP model results show that middle level motives were found to be most important for tourists with more diverse travel experience which include nature, self-development and self-actualisation. Signi ﬁ cant relationships were also found among the origin of tourists, their travel experiences and their motivational pattern.
Exploring aquaporin functions during changes in leaf water potential

Maintenance of optimal leaf tissue humidity is important for plant productivity and food security. Leaf humidity is influenced by soil and atmospheric water availability, by transpiration and by the coordination of water flux across cell membranes throughout the plant. Flux of water and solutes across plant cell membranes is influenced by the function of aquaporin proteins. Plants have numerous aquaporin proteins required for a multitude of physiological roles in various plant tissues and the membrane flux contribution of each aquaporin can be regulated by changes in protein abundance, gating, localisation, post-translational modifications, protein:protein interactions and aquaporin stoichiometry. Resolving which aquaporins are candidates for influencing leaf humidity and determining how their regulation impacts changes in leaf cell solute flux and leaf cavity humidity is challenging. This challenge involves resolving the dynamics of the cell membrane aquaporin abundance, aquaporin sub-cellular localisation and location-specific post-translational regulation of aquaporins in membranes of leaf cells during plant responses to changes in water availability and determining the influence of cell signalling on aquaporin permeability to a range of relevant solutes, as well as determining aquaporin influence on cell signalling. Here we review recent developments, current challenges and suggest open opportunities for assessing the role of aquaporins in leaf substomatal cavity humidity regulation.
Customizable 3D Printed Implants Containing Triamcinolone Acetonide: Development, Analysis, Modification, and Modeling of Drug Release

Three-dimensional-printed customizable drug-loaded implants provide promising opportunities to improve the current therapy options. In this study, we present a modular implant in which shape, dosage, and drug release can be individualized independently of each other to patient characteristics to improve parenteral therapy with triamcinolone acetonide (TA) over three months. This study focused on the examination of release modification via fused deposition modeling and subsequent prediction. The filaments for printing consisted of TA, ethyl cellulose, hypromellose, and triethyl citrate. Two-compartment implants were successfully developed, consisting of a shape-adaptable shell and an embedded drug-loaded network. For the network, different strand widths and pore size combinations were printed and analyzed in long-term dissolution studies to evaluate their impact on the release performance. TA release varied between 8.58 ± 1.38 mg and 21.93 mg ± 1.31 mg over three months depending on the network structure and the resulting specific surface area. Two different approaches were employed to predict the TA release over time. Because of the varying release characteristics, applicability was limited, but successful in several cases. Using a simple Higuchi-based approach, good release predictions could be made for a release time of 90 days from the release data of the initial 15 days (RMSEP ≤ 3.15%), reducing the analytical effort and simplifying quality control. These findings are important to establish customizable implants and to optimize the therapy with TA for specific intra-articular diseases.
Effects of a Subanesthetic Ketamine Infusion on Inflammatory and Behavioral Outcomes after Closed Head Injury in Rats

Traumatic brain injury (TBI) affects millions of people annually, and most cases are classified as mild TBI (mTBI). Ketamine is a potent trauma analgesic and anesthetic with anti-inflammatory properties. However, ketamine’s effects on post-mTBI outcomes are not well characterized. For the current study, we used the Closed-Head Impact Model of Engineered Rotational Acceleration (CHIMERA), which replicates the biomechanics of a closed-head impact with resulting free head movement. Adult male Sprague–Dawley rats sustained a single-session, repeated-impacts CHIMERA injury. An hour after the injury, rats received an intravenous ketamine infusion (0, 10, or 20 mg/kg, 2 h period), during which locomotor activity was monitored. Catheter blood samples were collected at 1, 3, 5, and 24 h after the CHIMERA injury for plasma cytokine assays. Behavioral assays were conducted on post-injury days (PID) 1 to 4 and included rotarod, locomotor activity, acoustic startle reflex (ASR), and pre-pulse inhibition (PPI). Brain tissue samples were collected at PID 4 and processed for GFAP (astrocytes), Iba-1 (microglia), and silver staining (axonal injury). Ketamine dose-dependently altered locomotor activity during the infusion and reduced KC/GRO, TNF-α, and IL-1β levels after the infusion. CHIMERA produced a delayed deficit in rotarod performance (PID 3) and significant axonal damage in the optic tract (PID 4), without significant changes in other behavioral or histological measures. Notably, subanesthetic doses of intravenous ketamine infusion after mTBI did not produce adverse effects on behavioral outcomes in PID 1–4 or neuroinflammation on PID 4. A further study is warranted to thoroughly investigate beneficial effects of IV ketamine on mTBI given multi-modal properties of ketamine in traumatic injury and stress.
Asset Pricing with Systematic Skewness: Two Decades Later

We reexamine the asset pricing performance of systematic skew-ness (“coskewness”), a risk factor in the three-moment CAPM model of Kraus and Litzenberger (1976). In an inﬂuential paper, Harvey and Siddique (2000) test a coskewness factor constructed by sorting stocks on past coskewness. We replicate and extend their paper. Overall, coskewness appears to be priced in the cross section of stocks, especially when using an alternative coskewness proxy like (i) the predicted systematic skewness ( PSS ) of Langlois (2020), where coskewness is predicted by various ﬁrm characteristics, or (ii) a modiﬁed PSS factor ( mPSS ) that uses only return-based characteristics.
Lipoprotein(a) as a Higher Residual Risk for Coronary Artery Disease in Patients with Type 2 Diabetes Mellitus than without

Purpose Lipoprotein(a) (Lp[a]) is well-known as a residual risk factor for coronary artery disease (CAD). However, the different adverse effects of Lp(a) about CAD in patients with or without type 2 diabetes mellitus (T2DM) are unclear. This study aimed to investigate the Lp(a) thresholds for CAD diagnosis in T2DM and non-T2DM patients, and further compare the Lp(a) alarm values along with optimal low-density lipoprotein cholesterol (LDL-C) level. Methods This retrospective study consecutively enrolled patients with suspected CAD who underwent coronary angiography in Guangdong Provincial People’s Hospital between September 2014 and July 2015. A logistic regression model was established to explore the association of Lp(a) and CAD in patients. Restricted cubic splines were used to compare the threshold values of Lp(a) for CAD in patients with and without T2DM, and further in optimal LDL-C level situation. Results There were 1522 patients enrolled finally. After multivariable adjustment, Lp(a) was an independent risk factor for CAD in patients with T2DM (odds ratio [OR]: 1.98, 95% CI]: 1.12–3.49, p = 0.019) and without T2DM (OR: 3.42, 95% CI: 2.36–4.95, p < 0.001). In the whole population, the Lp(a) threshold of CAD was 155, while 145 mg/L for T2DM and 162 mg/L for non-T2DM ones, respectively. In patients with LDL-C<1.8 mmol/l, the alarm value of Lp(a) was even lower in T2DM than non-T2DM patients (155 vs 174 mg/L). Conclusion Lp(a) was a significant residual risk for CAD in patients whether with T2DM or not. And Lp(a) had a lower alarm value in T2DM patients, especially in optimal LDL-C level.
Modeling Occupational Burnout Based on Job Stress With the Mediating Role of Psychological Capital and Coping Strategies Among Nurses

Background: Occupational burnout is one of the factors that can significantly decline the performance of nurses, and can be influenced by various factors. Objectives: The present study seeks to model occupational burnout based on job stress with the mediation of psychological capital and coping strategies used by nurses. Materials & Methods: The present correlational article falls into the category of descriptive-crosssectional studies. The population of the study includes all nurses working in public hospitals of Kermanshah province. A total of 404 nurses selected through random cluster sampling participated in the study. Demographic Information Questionnaire, Nursing Stress Scale, Maslach Burnout inventory, The Coping Inventory for Stressful Situations and psychological capital questionnaire were used for data collection purposes. The collected data were analyzed using SPSS software, version 24 and Amos software, version 24. Results: The results showed that the proposed model had an acceptable goodness of fit (χ2/df=3.05, GFI=0.90, CFI=0.93, RMSEA=0.07). The results suggest that occupational stress with the mediating role of problem -focused coping (β=0.028, P=0.001), emotion-focused coping (β=0.069, P=0.001), avoidant-oriented coping (β=0.046, P=0.001) and psychological capital (β=0.144, P=0.001) can indirectly affect nurses’ occupational burnout. Conclusion: Job stress affects nurses’ burnout directly as well as through the mediation of problem-focused coping, emotion-focused coping, avoidant-oriented coping and psychological capital. Accordingly, authorities are advised to organize training courses to improve coping strategies and psychological capital of nurses and thereby mitigate the effect of occupational stress.
Recent Excavations of Charcoal Production Platforms in the Glendalough Valley, Co. Wicklow

This paper presents the results of recent archaeological excavations in Lugduff townland, Co. Wicklow—a location better known as the Upper Lake, Glendalough. Excavations in 2009 targeted charcoal production sites on the southern valley slopes overlooking the lake. These have provided important data about the nature and timing of charcoal production and the associated woodland resource in the valley. We begin by presenting a background to charcoal production in Glendalough, before summarising the results of the excavations, presenting details of the charcoal analysis and closing with a discussion of the landscape implications of our work, especially in terms of the recent woodland history
MicroRNAs Derived from Extracellular Vesicles: Keys to Understanding SARS-CoV-2 Vaccination Response in Cancer Patients?

Simple Summary Despite the declaration of the end of the COVID-19 pandemic in May 2023, several important questions regarding its impact on public health remain unanswered. Specifically, the clinical trials for COVID-19 vaccines did not include cancer patients, leaving a knowledge gap about how vaccination affects this vulnerable population. Therefore, it is crucial to identify specific biomarkers that can help us understand and stratify cancer patients according to their SARS-CoV-2 vaccination responsiveness. Thus, a literature review was conducted to investigate the known extracellular vesicle-derived microRNAs involved in SARS-CoV-2 infection and how many that were already deregulated in the cancer context could also be involved in the vaccination response. However, further in-depth studies are necessary to fully comprehend and validate the role of these EV-miRNAs as potential biomarkers of cancer patients’ response to vaccination. Abstract Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) provoked a global pandemic identified as coronavirus disease (COVID-19), with millions of deaths worldwide. However, several important questions regarding its impact on public health remain unanswered, such as the impact of vaccination on vulnerable subpopulations such as cancer patients. Cytokine storm and a sustained inflammatory state are commonly associated with immune cell depletion, being manifested in most immunocompromised individuals. This strong immunosuppression can lead to a dysfunctional antiviral response to natural viral infection and compromised vaccination response. Extracellular vesicles (EVs) are membrane-bound vesicles released from cells that are involved in intercellular communication. EVs carry various molecules including microRNAs that play a crucial role in COVID-19 pathophysiology, influencing cellular responses. This review summarizes the state of the art concerning the role of EV-derived miRNAs in COVID-19 infection and their potential use as prognosis biomarkers for vaccination response in cancer patients.
Culture and Gender Influence Self-Construal in Mother-Preschooler Reminiscing

ABSTRACT The present study examined how culture and gender influence the self-construal of mothers and their four-year-olds during dyadic reminiscing. Participants were 21 Thai (11 girls, 10 boys) and 21 American (10 girls, 11 boys) mother-child dyads. Thai dyads exhibited a more interdependent self-construal, whereas American dyads exhibited a more independent self-construal, as measured by personal and group pronoun usage and discussions of behavioral expectations, thoughts and feelings, and personal attributes. Girls and boys differed in the extent to which their self-construal was defined in relation to others in their social groups, for example girls mentioned teachers and classmates more than boys. Culture and gender also interacted in influencing self-construal, with Thai girls (but not boys) mentioning family members more than American counterparts. These findings suggest that the development of children’s self-construal, particularly the extent to which children are socialized to view and express themselves independently of others or interdependently with others, differs depending on culture and gender. This work contributes to our understanding of the relationship between autobiographical memory and self during the formative years. Starting as early as preschool, our social environment influences the way we remember our experiences, which in turn shapes our self-construal.
Impact of the histologic grade of acute gastrointestinal graft-versus-host disease on outcomes in pediatric patients treated with allogeneic hematopoietic stem cell transplantation

Introduction Acute gastrointestinal graft-versus-host disease (GVHD) is a common life-threatening complication after hematopoietic stem cell transplantation (HCT). We aimed to investigate outcomes according to the clinical, endoscopic, and histologic severity of gastrointestinal GVHD in pediatric patients treated with allogeneic HCT. Methods This retrospective cohort study included pediatric patients who underwent sufficient endoscopic and histopathologic evaluation for clinically suspected acute gastrointestinal GVHD between 2010 and 2020. Results Fifty-one patients were included (male proportion, 68.6% [35/51]; median age at HCT, 6.4 years). When the patients were classified according to the histologic severity of gastrointestinal GVHD, the severe group had an earlier onset of GVHD symptoms and a higher proportion of patients with severe clinical gastrointestinal GVHD than the mild-to-moderate and “absent” groups. In Cox proportional hazards regression analysis, the groups with more severe clinical and histologic gastrointestinal GVHD showed a higher risk of non-relapse mortality (NRM). The 5-year overall survival (OS) rates were 58.3 and 36.4% in the mild-to-moderate and histologic gastrointestinal GVHD groups, respectively (p = 0.0384). Patients with higher clinical and histologic grades of gastrointestinal GVHD showed higher cumulative incidence of NRM. Discussion Our results demonstrated that histologic severity of gastrointestinal GVHD is a relevant factor affecting OS and NRM, and patients with mild-to-moderate or severe histologic gastrointestinal GVHD have worse outcomes than patients without histologic GVHD. These findings support the importance of assessing the histologic grade in the diagnostic evaluation of patients with clinical gastrointestinal GVHD.
Studies of ecological factors that affect the population and distribution of the western gray squirrel in northcentral Oregon

This Dissertation is brought to you for free and open access. It has been accepted for inclusion in Dissertations and Theses by an authorized administrator of PDXScholar. For more information, please contact pdxscholar@pdx.edu. Recommended Citation Foster, Susan Ann, "Studies of ecological factors that affect the population and distribution of the western gray squirrel in northcentral Oregon" (1992). Dissertations and Theses. Paper 2383.
Physical Activity and Exercise as a Tool to Cure Anxiety and Posttraumatic Stress Disorder

Anxiety and posttraumatic stress disorder (PTSD) are the most prevalent psychiatric conditions and significant public health problems. However, research has tended to support claims that engaging in physical activity (PA) has beneficial psychological effects. The objective of this review is to examine exercise and PA therapies as a kind of PTSD and anxiety treatment. Exercise has been shown in interventional trials to be both anxiolytic and antidepressive in healthy individuals. Exercise and PA therapies have a variety of benefits and varying degrees of efficacy in treating PTSD and anxiety symptoms. PA has been shown to promote physical health; psychological health and a growing body of studies indicate that PA and general health are associated with PTSD and anxiety. These findings led to recommendations for exercise interventions as a safe, efficient, and effective therapeutic option for treating anxiety and PTSD symptoms. Studies have not, however, demonstrated that they can lower anxiety to the same degree as psychotropic drugs. Additionally, the majority of published studies have significant methodological flaws, necessitating the need for additional research to determine the ideal exercise modalities, frequency, duration, and intensity for enhancing the beneficial benefits of exercise on anxiety and PTSD.
Etude sismotectonique du Péloponnèse et réponse sismique d'une vallée sédimentaire en Grèce du Nord

Partie 1 : Etude sismotectonique du Peloponnese. Durant l'ete 1986 nous avons installe un reseau sismologique de 46 stations couvrant l'ensemble du Peloponese. Sur plus de 1000 seismes, 750 sont localises a 10 km pres et 480 le sont a 5 km pres, 100 solutions focales ont ete determinees. La sismicite enregistree est essentiellement crustale (95%). La croute inferieure apparait comme une zone sismique a l'ouest et devient sismique a l'est. Les mecanismes au foyer indiquent un champ de contrainte compressiif oriente E-W dans la bordure occidentale. Immediatement a l'est de cette zone, le regime devient extensif, d'orientation N-S au nord puis NW-SE a E-W dans ! e sud et le sud-. ouest du Peloponnese. La, sismicite intermediaire definit la geometrie de ia subduction de la plaque Afrique sous le Peloponnese. Le plongement est oriente NE-SW scion un pendage de 10°, a 200 km des fosses ce pendage s'accentue brusquement (45 ° ). Les mecanismes au foyer montrent une tectonique extensive orientee NE-SW, avec un pendage identique a celui de la plaque plongeante. 2* partie: Reponse sismique d'une vallee sedimentaire. Durant deux semaines , en mai 1985, cinq stations sismologiques ont ete installees a travers une vallee situee a 50 km de Thessalonique ( Grece) . Les stations etaient placees sur les sediments et sur les bords rocheux de la vallee. A partir de seismes locaux et regionaux, nous avons calcule les rapports des spectres de Fourier obtenus aux differents sites. Pour les sites sedimentaires, les rapports montrent des . amplifications maximales de 8, pour un site rocheux elles atteignent 6. Les amplifications observees sont maximales lors de seismes locaux.Nous interpretons ces effets en fonction du contexte geologique local.
Effects of forest management on fish habitat and macroinvertebrates in northeast Oregon streams

approved: Henry A. Froehlich This study describes streams in the Blue Mountains and Wallowa Mountains of Northeastern Oregon in order to characterize the interactions between the terrestrial and aquatic ecosystems and to determine how logging affects those relationships. Five stream reach pairs, each consisting of an undisturbed reach and a similar reach flowing through an area where the riparian zone had been logged, along with six additional undisturbed reaches were studied. The riparian stand, large woody debris, stream channel morphology and the benthic macroinvertebrate community were measured at each reach. Large woody debris volume ranged from 91.1 to 284.0 m3/ha and was greater in the logged reaches than undisturbed reaches. Stream channel morphology, as indicated by the pool-riffle ratio, in the logged reaches was not significantly different than undisturbed reaches and percent pool area was less than 30 percent in all reaches. Macroinvertebrate density ranged from 146.6 to 963.2 individuals/sample and was greater in the logged reach of each stream pair. Community diversity, as expressed by the Shannon-Wiener Diversity Index, at logged reaches was not significantly different from that at undisturbed reaches. Although some differences were found between logged stream reaches and undisturbed reaches, there was no indication that overall fish habitat was greatly diminished or improved as a result of logging. Effects of Forest Management on Fish Habitat and Macrojnvertebrates in Northeast Oregon Streams by Joan Y. Carison A THESIS submitted to Oregon State University in partial fulfillment af the requirements for the degree of Master of Science Completed Commencement June 1989