Miracle-dz/UniFAR-FTUs huggingface dataset:
Isotope ratio study of Bronze Age samples from the Eurasian Caspian Steppes

This paper presents result of the isotope study of human, faunal and plant archaeological samples from Bronze Age kurgans and graves of the Eurasian Steppes. Isotope data reveal a very broad range of 13C and 15N values for the Bronze Age cultures. The more ancient a sample is in age, the lower are its 13C and 15N values. Stable isotope values of plants, animal and humans are very sensitive to climate change. Annual precipitation and temperature were key factors driving the overall isotope trend. The data obtained helped us propose two fodder models for domesticated animals and three diet models for humans. 13C and 15N values in animal bones indicate that different pastures were used by local mobile groups. Some archaeological plant samples dating to the period of aridization are characterized by very high 15N values. These were probably included in animal fodder, which was reflected in the isotope ratio of domesticated animals. Humans had a mixed diet, which is why regular patterns of changes in the isotope ratios of carbon and nitrogen are more subtle. There is a small group of humans from North Caucasus who consumed mainly vegetable foods (C3 plants) and the flesh/milk of domesticated animals. The diet system characteristic for the humans whose main area of occupation was the steppe included the flesh/ milk of herbivores, river and lake aquatic foods, and wild C3 plants. The third group of humans consumed marine food. The isotope data we have obtained demonstrate that the human diet system changed due to changes in economy, nature of exploited local food resources, and climate.
Rehabilitation after replantation of a non-work-related finger amputation without vascular 
anastosmosis – case report

Work in agriculture carries the risk of trauma as a result of mechanization (farm equipment and machinery), location of cultivated areas, and multi-functionality. In agriculture, the hands were the most affected parts of the body which sustained injury. Successful suturing of a finger initially disqualified from replantation is rare. The case is presented of a 55-year-old patient who had a non-work-related finger amputation. In a surgical centre not belonging to the reference ones in plastic surgery in Poland, a doctor with six months of surgical experience performed the replantation without vascular reconstruction (the amputated distal part of the finger served as a biological dressing). Despite the lack of vascular reconstruction and unfavourable prognosis, the amputated fragment of the finger maintained a partial blood supply. Subsequent flap surgery in the plastic surgery department, and rehabilitation of the patient due to finger contracture, led to functional recovery of the finger.
Research trends in drama therapy: a bibliometric analysis based on Scopus

Aim As drama therapy has become increasingly important in healthcare, the number of scientific publications has increased, complicating the orientation in the research field. Therefore, the aim of this study is to provide a comprehensive overview of research trends in drama therapy, assessing the impact factors of publications and analyzing the research structure. Methods Three hundred and ninety-five scientific articles indexed in Scopus were analyzed without time, geographic and language restrictions using bibliometric analysis methods - performance analysis, citation analysis, and science mapping. Data processing was performed using MS Excel, VOSviewer and Biblioshiny software. Results The work of the pioneers of drama therapy continues to be actively cited, influencing the development of drama therapy. Today’s leading researchers are increasingly engaging in collaborative research, working across disciplines and contributing to scientific progress. The hot topic of research is older adults and mental health. The diversity of terminology and the large volume of unpublished research point to the need for consolidation. Altmetric analysis would optimize the use of scientific information, promoting innovative research. Conclusion This is the first study using the Scopus database to perform an extensive bibliometric analysis of research articles on drama therapy applying Biblioshiny and VOSviewer software. The results of the analysis reflect the evolution of the field from its historical roots to academic maturity, highlighting its current dynamic growth and the trend of drama therapy to establish itself as an interdisciplinary field in the healthcare system. This work serves as a valuable resource for the scientific community, professionals, students, and librarians in the field, helping to optimize the use of scientific resources in drama therapy and contributing to its future development.
Rhizosphere Bacteria Plumeria acuminata Increases Growth of Zea mays After Root Inoculation

The bacteria found in the rhizosphere are called plant growth promoting rhizobacteria (PGPR), namely bacteria that can stimulate plant growth by producing growth hormones, one of which is the hormone indole acetic acid (IAA) which plays a role in regulating plant growth and development. Five isolates of rhizosphere bacteria were isolated on frangipani roots (P26, P31, P36, P37 and P38). Previous research showed that five bacterial isolates were capable of producing the hormone IAA. However, evidence of its potential as a PGPR has not been obtained. Therefore, the aim of this study was to test the effect of inoculation of rhizosphere bacteria on maize plants. The research method uses a quantitative experimental method, namely 15 repetitions for each treatment. Data collection was carried out 1 day after planting (HTS) until the 14th day. Data were analyzed using a 95% confidence student t-test or with a significance level of 5% (a=0.05). This inoculation begins with germinating maize seeds and observing the roots. The germinated maize seeds are then soaked in the bacterial suspension for one hour at room temperature. The results showed that inoculation with isolates P36, P37 and P38 significantly increased the height of maize plants, while isolate P37 significantly increased the number of leaves and root length of corn plants, isolate P38 could significantly increase the number of roots of corn plants.Thus, these results support the evidence that rhizosphere bacteria from frangipani have an effect on increasing the growth of maize plants
How Do Islamic University Prevent Fraud: Do Leadership Style and E-Procurement Matter

Internal control, and leadership style on fraud prevention at State Islamic Religious Universities in Indonesia. This study used the research subject, namely the Internal Supervisory Unit (SPI) at 58 PTKIN throughout Indonesia. The data used is primary data with a questionnaire technique that is distributed in the form of online, namely by using a google form which is sent via whatsapp to SPI PTKIN throughout Indonesia. The distribution of the questionnaire was carried out in two stages of filling out, namely 1) The First Phase, starting on June 15, 2022 to June 25, 2022, and 2) Phase Two, starting on June 30, 2022 until July 14, 2022. So that 102 respondents were obtained from 52 PTKIN. The analytical method used is multiple linear regression analysis which is processed using the SPSS version 25 program. Hypothesis testing is carried out simultaneously and partially, with the following results: (1) e-procurement implementation, internal control, and leadership style simultaneously affect fraud prevention, (2) e-procurement implementation has an effect on fraud prevention, (3) internal control has an effect on fraud prevention, and (4) leadership style has an effect on fraud prevention.
Polycythemia Vera: Barriers to and Strategies for Optimal Management

Abstract Polycythemia vera (PV) is a subtype of myeloproliferative neoplasms characterized by impaired quality of life and severe complications. Despite the increasingly in-depth knowledge of this condition, it necessitates a multifaceted management approach to mitigate symptoms and prevent thrombotic and hemorrhagic events, ensuring prolonged survival. The therapeutic landscape has been revolutionized in recent years, where venesection and hydroxycarbamide associated with antiplatelet therapy have a central role and are now accompanied by other drugs, such as interferon and Janus kinase inhibitors. Ongoing research and advancements in targeted therapies hold promise for further enhancing the therapeutic choice for PV management.
Protective Mechanisms of Polyphenol-Enriched Blueberry Preparation in Preventing Inflammation in the Skin against UVB-Induced Damage in an Animal Model

UVB significantly impacts the occurrence of cutaneous disorders, ranging from inflammatory to neoplastic diseases. Polyphenols derived from plants have been found to exhibit photoprotective effects against various factors that contribute to skin cancer. During the fermentation of the polyphenol-enriched blueberry preparation (PEBP), small oligomers of polyphenols were released, thus enhancing their photoprotective effects. This study aimed to investigate the protective effects of PEBP on UVB-induced skin inflammation. Topical preparations of polyphenols were applied to the skin of dorsally shaved mice. Mice were subsequently exposed to UVB and were sacrificed 90 min after UVB exposure. This study revealed that pretreatment with PEBP significantly inhibited UVB-induced recruitment of mast and neutrophil cells and prevented the loss of skin thickness. Furthermore, the findings show that PEBP treatment resulted in the downregulation of miR-210, 146a, and 155 and the upregulation of miR-200c and miR-205 compared to the UVB-irradiated mice. Additionally, PEBP was found to reduce the expression of IL-6, IL-1β, and TNFα, inhibiting COX-2 and increasing IL-10 after UVB exposure. Moreover, DNA methylation analysis indicated that PEBP might potentially reduce the activation of inflammation-related pathways such as MAPK, Wnt, Notch, and PI3K-AKT signaling. Our finding suggests that topical application of PEBP treatment may effectively prevent UVB-induced skin damage by inhibiting inflammation.
Initial Treatment with Biological Therapy in Rheumatoid Arthritis

Background: We aimed to analyse the effectiveness, efficiency, and safety of initial treatment with biological therapies in rheumatoid arthritis (RA). Methods: Qualitative study. A group of RA experts was selected. A scoping review in Medline was conducted to analyse the evidence of initial RA treatment with biological therapies. Randomised clinical trials were selected. Two reviewers analysed the articles and compiled the data, whose quality was assessed using the Jadad scale. The experts discussed the review’s findings and generated a series of general principles: Results: Seventeen studies were included. Most of the included patients were middle-aged women with early RA (1–7 months) and multiple poor prognostic factors. Initial treatment with TNF-alpha inhibitors combined with methotrexate (MTX) and an IL6R inhibitor (either in mono or combination therapy) is effective (activity, function, radiographic damage, quality of life), safe, and superior to MTX monotherapy in the short and medium term. In the long term, patients who received initial treatment with biologicals presented better results than those whose initial therapy was with MTX. Conclusions: Initial treatment of RA with biological therapies is effective, efficient, and safe in the short, medium, and long term, particularly for patients with poor prognostic factors.
Association between physical activity levels and healing in people with venous leg ulcers: secondary analysis of prospective cohort data

Aim To explore the relationship between physical activity levels and wound healing and recurrence in people with venous leg ulcers. Methods Questionnaires and medical records were used to collect data, with responses used to group participants into different physical activity groups. The differences in healing and recurrence outcomes of ulcers among different physical activity groups were compared using Chi-square, Kaplan Meier survival analysis, Cox proportional hazards regression analysis, and Kruskal-Wallis test. To measure the strength of the association between physical activity levels and patient outcomes, Spearman’s Rho tests were used. We used descriptive analysis to examine how physical activity levels change over 24 weeks. Results Participants were classified into four distinct groups based on physical activity levels reported at baseline and week 12. The survival analysis showed higher physical activity level was associated with a shorter time to healing (log-rank test = 14.78, df = 3; p = 0.002). The persistently moderate-to-vigorous group had a 7.3-fold increased likelihood of healing compared to the persistently sedentary group. High levels of physical activity were also associated with a better quality of life score at baseline ( ρ = 0.41, p < 0.000), week 12 ( ρ = 0.36, p < 0.001), and week 24 ( ρ = 0.49, p < 0.000). Most participants (48.5%) reported low levels of physical activity, which remained low for the entire study period. Conclusion An increased level of physical activity was linked to a shorter healing time and enhanced quality of life. Low levels of physical activity appeared common among people with venous leg ulcers.
Pollen and macrofossil‐inferred palaeoclimate at the Ridge Site, Hudson Bay Lowlands, Canada: evidence for a dry climate and significant recession of the Laurentide Ice Sheet during Marine Isotope Stage 3

We examine pollen, macrofossils and sedimentological proxies from the Ridge Site, an 18‐m sequence of glacial and non‐glacial sediments exposed along the bank of the Ridge River in the southern Hudson Bay Lowlands (HBL), Canada. As the HBL is located in the previously glaciated region of North America, palaeorecords from this region have important implications for understanding ice‐sheet palaeogeography and climate for the late Pleistocene. Two diamicton units were interpreted as subglacial till deposited by a glacier flowing toward the south‐southwest (lower diamicton) and west‐southwest (upper diamicton), respectively. Confined between these tills is a 6‐m non‐glacial unit, constrained to Marine Isotope Stage 3 (MIS 3; c. 57 000 to c. 29 000 a BP) by three radiocarbon dates. Quantitative analyses of the pollen record (dominated by Sphagnum, Cyperaceae, Pinus, Picea, Salix, Alnus and Betula) suggest that average summer temperature (June, July, August) was 14.6±1.51 °C, which is similar to that of the present day at the site. Total annual precipitation was 527±170 mm as compared to 705 mm present‐day. The macrofossil record confirmed the local presence of Betula, Salix and conifers. Our results, in combination with other records from the periphery of the Laurentide Ice Sheet, suggest that vast boreal forest‐type vegetation, along with a drier interstadial climate, existed in the region during MIS 3. We also compare pollen‐derived palaeoclimate reconstructions from the Ridge Site with reconstructions from a previously published site along the Nottaway River, HBL, which was dated to MIS 5a–d (c. 109 000 to c. 82 000 a BP). This comparison suggests that, with additional data, it may be possible to differentiate MIS 3 and MIS 5 deposits in the HBL on the basis of relative continentality, with MIS 3 characterized by lower total annual precipitation, and MIS 5 by values similar or greater than present‐day.
How incidental and intentional news exposure in social media relate to political knowledge and voting intentions

Background Citizens are expected to make informed voting decisions. Theoretical approaches suggest that people are most likely to acquire their political knowledge through media. As more people turn to social media as a source of news, the political knowledge gains from using these technologies are called into question. Previous research has shown that rather than increasing objective political knowledge, the use of social media for news only increases people’s metacognitive sense of being knowledgeable (subjective knowledge), which in turn increases their political participation. However, it remains to be understood which particular forms of social media use, e.g., incidental or intentional news exposure, are related to which dimension of political knowledge. The present work examines (a) the extent to which different motivational forms of social media news consumption foster subjective knowledge, and (b) whether this metacognition is related not only to political participation as a broad concept, but also to specific democratic outcomes such as voting intentions. Methods and results Results from a pre-registered, pre-election survey (N = 1,223) of social media users show that intentional news seeking, but not incidental news exposure on social media, is directly related to increased subjective knowledge. Subjective knowledge appears to explain the relationship between social media news use and voting. Discussion By showing that incidental and intentional social media news use affect subjective knowledge differently, this study provides preliminary and nuanced insights into the ultimate role that social media technologies can play in democratic processes.
EFEKTIVITAS PENGENDALIAN INTERNAL, DAN KOMPETENSI SUMBER DAYA MANUSIA, TERHADAP IMPLEMENTASI GOOD GOVERNANCE SERTA IMPIKASINYA PADA PENCEGAHAN FRAUD DALAM PENGELOLAAN KEUANGAN DESA DI KABUPATEN TANGERANG

Penelitian ini dilakukan untuk untuk mengetahui dan menganalisispengaruh sistem pengendalian internal, dan kompetensi sumber dayamanusia, terhadap implementasi good governance serta impikasinyapada pencegahan Fraud dalam pengelolaan keuangan desa diKabupaten Tangerang. Sampel dalam penelitian ini adalah perangkatdesa sebanyak 150 responden dengan metode purposive sampling.Teknik analisis data yang digunakan dalam penelitian ini adalah analisiskuantitatif dengan menggunakan model SEM (Structural EquationModelling) program AMOS 22. Hasil dari penelitian ini menunjukkanbahwa adanya pengaruh yang positif sistem pengendalian internal, dankompetensi sumber daya manusia, terhadap implementasi goodgovernance serta impikasinya pada pencegahan Fraud dalampengelolaan keuangan desa di Kabupaten Tangerang secara signifikan.Interpretasi dari hasil penelitian ini akan memiliki arti yang pentinguntuk menentukan strategi yang jelas dalam meningkatkan pencegahanFraud dalam pengelolaan keuangan Desa di Kabupaten Tangerang darihasil perhitungan pengaruh langsung, tidak langsung dan pengaruhtotal menghasilkan nilai kebaharuan dari sebuah teori dan empirisnya.
Human Precision-Cut Liver Slices: A Potential Platform to Study Alcohol-Related Liver Disease

Alcohol-related liver disease (ALD) encompasses a range of pathological conditions that are complex to study at the clinical and preclinical levels. Despite the global burden of ALD, there is a lack of effective treatments, and mortality is high. One of the reasons for the unsuccessful development of novel therapies is that experimental studies are hindered by the challenge of recapitulating this multifactorial disorder in vitro, including the contributions of hepatotoxicity, impaired lipid metabolism, fibrosis and inflammatory cytokine storm, which are critical drivers in the pathogenesis of ALD in patients and primary targets for drug development. Here, we present the unique characteristics of the culture of human precision-cut liver slices (PCLS) to replicate key disease processes in ALD. PCLS were prepared from human liver specimens and treated with ethanol alone or in combination with fatty acids and lipopolysaccharide (FA + LPS) for up to 5 days to induce hepatotoxic, inflammatory and fibrotic events associated with ALD. Alcohol insult induced hepatocyte death which was more pronounced with the addition of FA + LPS. This mixture showed a significant increase in the cytokines conventionally associated with the prototypical inflammatory response observed in severe ALD, and interestingly, alcohol alone exhibited a different effect. Profibrogenic activation was also observed in the slices and investigated in the context of slice preparation. These results support the versatility of this organotypic model to study different pathways involved in alcohol-induced liver damage and ALD progression and highlight the applicability of the PCLS for drug discovery, confirming their relevance as a bridge between preclinical and clinical studies.
The Relationship between Job Satisfaction and Turnover Intentions among Faculty Members in Ethiopian Higher Education Institutions

The main objective of this study was to investigate the relationship between job satisfaction and turnover intentions among faculty members in Ethiopian public higher education institutions. A quantitative correlational survey design was employed, and a total of 382 participants were selected through stratified random sampling from five universities of Ethiopian public higher education institutions. To analyze the data, a descriptive approach was used to summarize the findings, while inferential analysis involved correlation and multiple regressions to examine the associations between the variables. The results showed that both intrinsic and extrinsic job satisfaction were significantly associated with turnover intentions. From this finding, it is recommended that the university administration, in collaboration with the Ministry of Education (MoE), takes appropriate measures to ensure that faculty members receive adequate intrinsic and extrinsic job rewards. This will contribute to higher job satisfaction and reduce turnover intentions among academic staff. By addressing these factors, the institutions can retain their valuable workforce.
The pacing differences in performance levels of marathon and half-marathon runners

Introduction Many studies indicate a considerable impact of optimal pacing on long-distance running performance. Given that the amount of carbohydrates in metabolic processes increases supralinearly with the running intensity, we may observe differences between the pacing strategies of two long-distance races and different performance levels of runners. Accordingly, the present study aimed to examine the differences in pacing strategies between marathon and half-marathon races regarding the performance levels of runners. Methods The official results and split times from a total of 208,760 (marathon, N = 75,492; half-marathon, N = 133,268) finishers in the “Vienna City Marathon” between 2006 and 2018 were analyzed. The percentage of the average change of speed for each of the five segments (CS 1–5), as well as the absolute change of speed (ACS) were calculated. The CS 1–5 for the marathon are as follows: up to the 10th km, 10th – 20th km, 20th – 30th km, 30th – 40th km, and from the 40th km to the 42.195 km. For the half-marathon, the CS 1–5 are half of the marathon values. Four performance groups were created as quartiles of placement separately for sexes and races: high-level (HL), moderate to high-level (MHL), moderate to low-level (MLL), and low-level (LL). Results Positive pacing strategies (i.e., decrease of speed) were observed in all performance groups of both sex and race. Across CS 1–5, significant main effects (p < 0.001) were observed for the segment, performance level, and their interaction in both sex and race groups. All LL groups demonstrated higher ACS (men 7.9 and 6.05%, as well as women 5.83 and 5.49%, in marathon and half-marathon, respectively), while the HL performance group showed significantly lower ACS (men 4.14 and 2.97%, as well as women 3.16 and 2.77%, in marathon and half-marathon, respectively). Significant main effects (p < 0.001) for the race were observed but with a low effect size in women (ŋ2 = 0.001). Discussion Better runners showed more even pacing than slower runners. The half-marathoners showed more even pacing than the marathoners across all performance groups but with a trivial practical significance in women.