Miracle-dz/UniFAR-FTUs huggingface dataset:
EVALUATING DEGREE OF COMPACTION OF LEVEES USING CONE PENETRATION TESTING

Permeability and strength parameters of compacted soils (i.e., levees as well as other earthworks) may be correlated to the degree of compaction. Since the use of conventional and recent testing methods for the assessment of density and water content of earthworks, under construction, cannot be applied to existing levees, an expeditious and accurate method for the assessment of the degree of compaction of existing and new levees, after their completion, appears extremely useful. The purpose of this research is to develop a simple tool for the assessment of the degree of compaction of “compacted”, partially saturated, fine grained soils. This paper illustrates the proposed method which combines in situ testing such as electric CPT or CPTu with laboratory penetration testing performed with a mini-cone in a calibration chamber (CC).
Pengaruh Pengetahuan Keuangan, Sikap Keuangan, dan Kepribadian terhadap Perilaku Manajemen Keuangan

Abstract. This study aims to determine the effect of financial knowledge, financial attitudes, and personality on financial management behavior in animal feed and fishing equipment Kadipaten Village Tasikmalaya District in 2021, either partially or simultaneously. The method used in this research is quantitative descriptive and verification with data collection techniques using questionnaires, observation, and documentation. The population in this study were 1.128 people for animal feed and fishing equipment in the Kadipaten Village, Tasikamalaya Regency and 92 samples were taken who met the sample selection criteria. The analysis technique used in this study uses the classical assumption test, linear regression, t test, F test, and the coefficient of determination. The partial test results show that financial knowledge, financial attitudes, and personality affect financial management behavior, and simultaneous testing shows that financial knowledge, financial attitudes, and personality affect the financial management behavior of Animal Feed and Fishing Equipment Kadipaten Village Tasikmalaya District in 2021. Abstrak. Penelitian ini bertujuan untuk megetahui pengaruh pengetahuan keuangan, sikap keuangan, dan kepribadian terhadap perilaku manajemen keuangan pada pelaku UMKM pakan ternak dan alat pancing Desa Kadipaten Kabupaten Tasikmalaya tahun 2021 baik secara parsial maupun simultan. Metode yang digunakan dalam penelitian ini adalah kuantitatif deskriptif dan verifikatif dengan teknik pengumpulan data menggunakan kuesioner, observasi, dan dokumentasi. Populasi dalam penelitian ini yaitu pelaku UMKM pakan ternak dan alat pancing Desa Kadipaten Kabupaten Tasikamalaya sebanyak 1.128 jiwa dan sampel yang diambil sebanyak 92 jiwa yang memenuhi kriteria pemilihan sampel. Teknik analisis yang digunakan dalam penelitian ini menggunakan uji asumsi klasik, regresi linier, uji t, uji F, dan koefisien determinasi. Hasil pengujian secara parsial menunjukkan bahwa pengetahuan keuangan, sikap keuangan, dan kepribadian berpengaruh terhadap perilaku manajemen keuangan, serta pengujian secara simultan menunjukkan bahwa pengetahuan keuangan, sikap keuangan, dan kepribadian berpengaruh terhadap perilaku manajemen keuangan para pelaku UMKM dalam bidang pakan ternak dan alat pancing Desa Kadipaten Kabupaten Tasikmalaya tahun 2021.
PCR analysis of CMV in hematology patients

Objectives: In this study we aimed to analyze cytomegalovirus (CMV) deoxyribonucleic acid (DNA) polymerase chain reaction (PCR) results in non-transplant patients. Patients and methods: Although we do not currently perform bone marrow transplant (BMT), we conducted a retrospective analysis of CMV DNA PCR monitoring (twice-weekly) of 91 hospitalized patients (with 306 peripheral blood) (47 males, 44 females; mean age 62+2.3 year; range, 25 to 85 year). For this purpose, we reviewed CMV DNA PCR records of patients in our clinic. Results: The results of CMV DNA PCR in 91 non-transplant patients are analyzed retrospectively in this study. CMV DNA PCR test results were positive in 10 patients (a total of 17 peripheral blood) while negative in 81 patients (a total of 289 peripheral blood). We did not begin antiviral therapy in patients with positive CMV DNA PCR results. Because it is incompatible with the patients’ clinical CMV DNA PCR positive CMV infection. None of the 91 patients enrolled in the study are transplant recipients, and they did not receive alemtuzumab treatment. Three of 10 CMV DNA PCR-positive patients had multiple myeloma (MM) with renal failure. One of the MM patients was diabetic. Three patients were diagnosed with acute myeloblastic leukemia and received chemotherapy; two patients were diagnosed with immune thrombocytopenic purpura; one patient was diagnosed with chronic lymphocytic leukemia, and one patient received therapy for the diagnosis of aplastic anemia. They were given treatment protocols based on their diagnosis. None of our patients has specific clinical CMV infection clinical findings. Conclusion: We conclude that close CMV DNA PCR monitoring in non-transplant hematology patients is not cost-effective. Even though it is not recommended for other hematology patients, close monitoring of CMV DNA PCR is still performed in many clinics in Turkey, and we suspect it is still performed in clinics abroad.
Upper Aptian nautiloids from Colombia

"Three new species of nautiloids, Cymatoceras colombiana, Eutrephoceras laverdei, and Heminautilus etheringtoni, are described from the upper Aptian [Cretaceous] of Colombia. Heminautilus etheringtoni is discussed at some length and compared with H. stantoni (Scott) and H. lallieranus (d9Orbigny). "
Cognitive Regulation Strategies Used by Children with Reading Difficulties

(1) Background: Children with reading difficulties may experience negative emotions and social isolation. The cognitive emotion regulation strategies that they use in different reading tasks can make them more vulnerable in the stressful situations. Using adaptative emotion regulation strategies may help them overcome stressful reading situations. (2) Methods: Children identified with poor reading comprehension skills were compared to children without reading comprehension difficulties on measures of self-evaluation and thought in relation to task, and on cognitive coping strategies relevant to performance. The effect of some relevant demographic factors was also investigated, such as gender and urban/rural setting. (3) Results: Our results indicate that children that have poor reading comprehension skills present higher scores on negative self- evaluation and off-task thoughts that are in relation to performance anxiety. Also, in what concerns cognitive coping strategies, students with difficulties in reading comprehension display a greater use of blaming others strategy, which is in relation to the negative self-evaluations. Also, they displayed less use of putting into perspective. No effect of gender and setting emerged for off and on task thoughts and cognitive coping strategies, except for lower scores of students from rural setting in positive self-evaluation. (4) Conclusions: students presenting difficulties in reading comprehension tend to use more negative self-statements and disengagement through off-task thoughts and employ coping strategies directed to protect self-worth.
Concurrent Validation of MI-CAT(V), a Clinical Metrology Instrument for Veterinarians Assessing Osteoarthritis Pain in Cats, through Testing for Firocoxib Analgesic Efficacy in a Prospective, Randomized, Controlled, and Blinded Study

Simple Summary Feline osteoarthritis (OA) diagnosis depends greatly on owner perception and experience of the disease. Owners frequently consider the emergence of OA (delayed and severe) signs as “normal” for an aged cat. Being an incurable, progressive, degenerative process, OA will require life-long treatment. There is a need for a rapid, reliable, and inexpensive diagnostic tool that reveals feline OA pain. A refined scale, the Montreal Instrument for Cat Arthritis Testing, for Use by Veterinarians (MI-CAT(V)) presented remarkable metrological properties (specific, sensitive, and reliable) over its development and validation process. In particular, MI-CAT(V) was responsive to a treatment with firocoxib, a non-steroidal anti-inflammatory drug (NSAID), and discriminated four degrees of OA pain functional severity. Firocoxib presented a clear treatment effect based on the MI-CAT(V) and on other functional objective assessments, including possible dose-response. The NSAID was safe over the three-week daily administration tested period. The cluster repartition offers new perspective for an individualized treatment care. Abstract Veterinarians face the lack of a rapid, reliable, inexpensive, and treatment-sensitive metrological instrument reflecting feline osteoarthritis (OA) pain. The Montreal Instrument for Cat Arthritis Testing, for Use by Veterinarians (MI-CAT(V)) has been refined in 4 sub-sections, and we proposed its concurrent validation. Cats naturally affected by OA (n = 32) were randomly distributed into 4 groups of firocoxib analgesic (Gr. A: 0.40; B: 0.25; C: 0.15, and P: 0.00 mg/kg bodyweight). They were assessed during Baseline, Treatment, and Recovery periods using MI-CAT(V) and objective outcomes (effort path, stairs assay compliance, and actimetry). The MI-CAT(V) total score correlated to the effort path and actimetry (RhoS = −0.501 to −0.453; p < 0.001), also being sensitive to treatment responsiveness. The pooled treatment group improved its total, gait, and body posture scores during Treatment compared to the Baseline, Recovery, and placebo group (p < 0.05). The MI-CAT(V) suggested a dose-(especially for Gr. B) and cluster-response. Cats in the moderate and severe MI-CAT(V) clusters responded to firocoxib with a remaining analgesic effect, while the mild cluster seemed less responsive and experienced a negative rebound effect. The MI-CAT(V) was validated for its OA pain severity discriminatory abilities and sensitivity to firocoxib treatment, providing a new perspective for individualized care.
Role of blank moisturisation in press forming of paperboard

To investigate the influence of blank moisture on the forming of paperboard, press forming experiments were performed with fixed blank setup and sliding blank setup to produce paperboard trays. The trays were rated by their forming height. Different moisturisation procedures were established to achieve one or double-sided surface moisturisation or homogenous moisture distributions in the blanks. Additionally, basic influences of moisture to paper-to-metal friction and tensile properties of the paperboard were measured. Surface moisturisation increased the paper-to metal friction and therefore limited the achievable forming heights in sliding blank press forming. The elongation at break of paperboard increased with increased sample moisture content. In the fixed blank press forming test this increase was not apparent in the data.
A Corpus-Assisted Analysis of Conceptual Metaphors in K-Beauty Metaphoric Advertising

Over the past few decades, the Conceptual Metaphor theory has attracted scholarly and practitioner attention in the construction of metaphoric advertising, which is driven by the claim that abstract concepts intended to be delivered are better communicated through a conceptual metaphor (Reddy 1979). Metaphoric advertising is a communicative mechanism that sends out intended messages while also provoking positive emotions and triggering attention from the recipient. In order to augment prior findings, this article aims to provide the metaphorical account of a conceptual mechanism delineated in K-Beauty metaphoric advertising by classifying their sub-types into structural, orientational, and ontological metaphors. To that end, this study compiled the K-Beauty metaphoric advertising corpora, which held over four thousand tokens of slogans and taglines extracted from beauty product advertisements generated in translated English, thus aiming to discuss primary instances of metaphorical mappings and conceptualizations, as well as their persuasive functions. Overall, the results evidenced that structural metaphors outperformed the other two sub-types, typifying systematic qualities and rich source domains. Of all the conceptual metaphor sub-categories, it was observable that the ENTITY and SUBSTANCE metaphors, which are a sub-type of ontological metaphors, were the most robust, signifying that ontological metaphors may adopt an imaging mechanism to transfer metaphorical mappings from a source domain to a target domain. The findings argue that particular metaphor choices in metaphoric advertising are closely linked to a cognitive mechanism triggered by cultural awareness pertaining to persuasion and promotion. Based on the current findings, implications and future research directions will also be discussed.
An examination of development models for innovative, low carbon, ecological dwellings for rural areas of Wales

The provision of housing in rural areas has been identified as crucial for the long term sustainability of rural communities. However, there are questions about how rural developers are responding to legislative requirements to reduce carbon emissions, whether the fulfilment of a need for affordable housing in rural areas can be reconciled with higher energy performance and whether higher energy performance will affect thermal comfort when climate change is taken into account. To understand these issues a review of published and monitored case studies in rural areas of the UK was undertaken which highlighted a number of development models that might be applied by house builders in the Welsh context. An analysis of two exemplar projects in Pembroke Dock, West Wales, examined the following: the social, economic and legislative context of rural development; the significance of energy and carbon used to construct rural houses; and the quantity of energy required to keep rural dwellings at a comfortable temperature in a typical year. Dynamic thermal modelling was then used to investigate a number of design approaches highlighted in the earlier studies as significant including: increasing thermal mass; increasing south facing glazing; adjusting building form and the layout of the site; and higher levels of insulation. The application of these approaches on a housing scheme in West Wales established the benefits of incorporating thermal mass into the building fabric, maintaining a compact form and, where reasonable, using passive solar gain, to reduce heating load. This study identified that these approaches, if carefully combined, could achieve significant (i.e. 16.4%-29.8%) reductions in heating load without compromising the affordability of the original scheme. However, the study also identified that one possible consequence of improving the energy performance would be a reduction in thermal comfort as a result of higher internal temperatures. To gain a better understanding of this further modelling examined the potential for overheating using the following: current and future climate files; an algorithm based on window opening behaviour; detailed simulation of airflow; and bivariate data analysis techniques. The results from this study identified that thermal mass and ventilation techniques could be employed to address the issues of overheating.
Epidemiology and Incidence of Upper Limb Fractures: A UK Level 1 Trauma Center Perspective

Introduction Understanding the incidence and epidemiology can inform clinicians and policymakers about the population's needs. Our study reports on upper limb fractures treated at a major trauma center over 7.5 years. Methods We collected data on fracture locations, age, gender, Charlson Comorbidity index (CCI), and treatment options of all upper limb fractures treated at a Level I Trauma Centre from January 1, 2015 to June 30, 2022. Humerus, radius, and ulna fractures were each classified as proximal, diaphyseal, and distal. Results About 9,915 patients sustained 12,790 fractures, given an overall incidence of 303.2 fractures per 100,000 patients per year. The most common fracture site was the distal radius (60.1 fractures per 100,000 patients per year, whereas carpal and metacarpal bones had the lowest incidence. The mean age and CCI were 46.4 years and 1.54, respectively. 58.1% of patients were male. All bone fractures distal to the elbow were associated with an age younger than the mean (all p<0.001), with humerus fracture patients having the oldest mean age (54.6 years). Compared to the mean gender ratio, except for ulna (no association), humerus (55% female), and radius (51% female), all other locations showed significantly higher incidences of males (all p<0.001). When plotting the incidence based on the age of injury, the entire cohort, along with radius and ulna fracture subgroups, demonstrated a bi-peak distribution. This pattern revealed that younger males and older postmenopausal females had the highest incidence rates. Conclusion To our knowledge, this represents the first study of this type in the UK since 2006. We sought to elucidate relative incidence and demographic associations with fractures to highlight changing population needs and allow policymakers and services at a regional and national level to operate with up-to-date information.
Antibody-Drug Conjugates in Breast Cancer: A Comprehensive Review of How to Selectively Deliver Payloads

Abstract Antibody-drug conjugates (ADCs) have surfaced as a promising group of anticancer agents employing the precise targeting capacity of monoclonal antibodies to transport highly effective cytotoxic payloads. Compared to conventional chemotherapy, they aim to selectively eradicate cancer cells while minimizing off-target toxicity on healthy tissues. An increasing body of evidence has provided support for the efficacy of ADCs in treating breast cancer across various contexts and tumor subtypes, resulting in significant changes in clinical practice. Nevertheless, unlocking the full potential of these therapeutic agents demands innovative molecular designs to address complex clinical challenges, including drug resistance, tumor heterogeneity, and treatment-related adverse events. This thorough review provides an in-depth analysis of the clinical data on ADCs, offering crucial insights from pivotal clinical trials that assess the efficacy of ADCs in diverse breast cancer settings. This aids in providing a comprehensive understanding of the current state of ADCs in breast cancer therapy, while also providing valuable perspectives for the future.
Characteristics of Safety Personality

For high-risk organisations, it is essential that employees demonstrate safety-awareness behaviour, as a reflection of their safety personality, to avoid accidents. Several studies confirm that personality is the individual difference that is most associated with the likelihood of an accident occurring; it is therefore necessary to address the identification and expression of the characteristics of safety personality. This paper aims to present a personality questionnaire the authors have created, which was administered to employees of a large Hungarian company in the electricity supply business with altogether 1273 employees obligated to prioritise workplace safety. The final version of the questionnaire contained 59 items. Based on the statistical results, 58.08% of the variance of total variables was explained by 10 factors; the scales of the questionnaire developed are otherwise reliable. The paper also examines the validation of the scales using different psychological measures.
Production and characterization of an extracellular Mn2+ activated ß-D-fructofuranosidase from Aspergillus labruscus ITAL 28.255 with transfructosylating activity

Fungal ß-D-fructofuranosidases present biotechnological potential for use in food, beverage, and pharmaceutical industries. In light of this, the best culture conditions for the production of ß-D-fructofuranosidase by Aspergillus labruscus ITAL 28.255 were obtained with an M-5 medium maintained at 30°C and 100 rpm for 120 h. The use of a mixture of rye flour and sucrose (1.5:0.5, m/m) and 2% yeast extract as the carbon and nitrogen sources, respectively, proportioned the best production of the enzyme. The extracellular ß-D-fructofuranosidase was purified 17-fold, with 9% recovery, and was characterized as a glycoprotein with 67 kDa (SDS-PAGE) and 40.7% carbohydrate content. The best temperature and pH for enzyme activity were 55°C and 5.5, respectively. The enzyme activity was maintained around 75% at 40 and 50°C for 1 h, with a half-life of 5 min at 70°C. The hydrolytic activity was increased in the presence of Mn2+. The Vmax and KM were 4.74 mM and 140.3 U/mg using sucrose; while, in the presence of Mn2+, the KM was 2.17 mM and the Vmax was 292.9 U/mg. The enzyme performed the transfructosylation reaction, enabling the production of FOS, mainly 1-kestose. This is the first report on the potential of A. labruscus to produce β-fructofuranosidase with transfructosylation activity.
Genetic dissimilarity, attributes association, and path analysis of sweet peppers

The present investigation was conducted on genetic diversification, character connections, and their direct and indirect effects using 21 sweet pepper genotypes to identify superiors owing to developing variety (es) and/or utilizing the pertinent genotypes in the hybridization program. It was found that, except fruit length (FL), all of the features had larger phenotypic coefficients of variation (PCV) than genotypic variation coefficients of variation (GCV), and the gap between PCV and GCV was rather small. Except for FL (24.98%) and seed number per fruit (24.76%), all traits had a high estimation of broad sense heritability of more than 75.00%, indicating significant improvement is possible by employing standard selection procedures. High genetic advance as a percentage of the mean was observed for all the characters. Genotypic and phenotypic correlation analyses showed that there was a strong positive correlation between fruit yield per plant with fruit yield/plot and yield (t/ha) (r = 1.00**). In addition, the importance and close correlation of characters to enhance yield or to use as selection catalogues were demonstrated by the fact that the genotypic direct impacts utilized by the yield component traits were fairly bigger than their equivalent phenotypic effects.