Miracle-dz/UniFAR-FTUs huggingface dataset:
Social preferences based on sexual attractiveness: a female strategy to reduce male sexual attention

Male sexual harassment of females is common across sexually reproducing species and can result in fitness costs to females. We hypothesized that females can reduce unwanted male attention by constructing a social niche where their female associates are more sexually attractive than themselves, thus influencing the decision-making of males to their advantage. We tested this hypothesis in the Trinidadian guppy (Poecilia reticulata), a species with high levels of male sexual harassment. First, we confirmed that non-receptive females were harassed less when they were paired with a more sexually attractive (receptive) female than with another non-receptive female. We then found that, indeed, females exploit this as a strategy to reduce sexual harassment; non-receptive females actively preferred to associate with receptive over non-receptive females. Importantly, when given access only to chemosensory cues, non-receptive females still showed this preference, suggesting that they use information from chemical cues to assess the sexual attractiveness of potential female partners. Receptive females in contrast showed no such preferences. Our results demonstrate that females can decrease male harassment by associating with females that are more sexually attractive than themselves and that they perform active partner choices based on this relative attractiveness. We propose that this strategy is likely to represent an important pathway by which females can construct social niches that influence the decision-making of others to their advantage; in this case, to reduce the sexual harassment they experience.
A construction of channel code, joint source-channel code, and universal code for arbitrary stationary memoryless channels using sparse matrices

A channel code is constructed using sparse matrices for stationary memoryless channels that do not necessarily have a symmetric property like a binary symmetric channel. It is also shown that the constructed code has the following remarkable properties: 1) Joint source-channel coding: Combining with lossy source code, which is also constructed by sparse matrices, a simpler joint source-channel code can be constructed than that constructed by the ordinary block code. 2) Universal coding: The constructed channel code has a universal property under a specified condition.
Long non-coding RNAs: New biomarkers for prognosis and diagnosis of colon cancer

Dysregulation of long non-coding RNAs has been found in many human cancers, including colorectal cancer that is still the third most prevalent cancer worldwide and related to poor prognosis; along with this, robust testimony has identified that long non-coding RNAs can take charge of tumor suppressor genes or oncogenes. This review summarizes nowadays research achievements on the character of long non-coding RNAs in the prognosis and diagnosis of colorectal cancer. On the basis of the results acquired in the last decade, some long non-coding RNAs are rising as biomarkers of colorectal cancer for prognosis, diagnosis, even prediction of therapeutic result, and have crucial effects in the regulation of colorectal cancer cell functions such as proliferation, invasion, apoptosis, metastasis, and drug resistant ability. Also, long non-coding RNAs, circulating in body fluids, could act as novel, affordable, lightly accessible, non-invasive detection tools for the personal health management of patients with colorectal cancer. Especially, circulating long non-coding RNA profiles may be demonstrating preferable prognostic and diagnostic capability and better accuracy than respective long non-coding RNAs in colorectal cancer.
A classification method of epithelial cells and clue cells based on multi-scale texture analysis

A novel method is proposed for the classification of epithelial cells and clue cells in wet mount microscopic images of vaginal secretions. Generally, there are many complicated ingredients in these images, and different from the gram stain method, no color information can be used. Obviously, the texture information of these cells becomes the main feature in the classification of these ingredients. After careful observation of difference of these two kinds of cells, we found the surface of clue cells is rougher. So, we extract texture features of those cells using the multi-scale texture energy descriptor which can reflect the difference of these two kinds of cells in different scales effectively. After that, the traditional SVM classifier is employed for the classification. The experimental results show that our method can effectively complete the classification task.
Critical metals in end-of-life products : Recovery potential and opportunities for removal of bottlenecks of recycling

Critical raw materials (CRM) are used in various applications in different sectors, and their consumption will likely further increase in future. The threats caused by their limited availability and high prices have led to discussion on more efficient use of the resources available. The enhanced recycling of critical raw materials could be a significant opportunity for the Nordic countries.This report focuses on the recycling potential of wastes containing CRMs, analyses of the bottlenecks of recycling, and identifies potential policy instruments to eliminate the barriers or reduce their impact. In order to enhance sustainable recycling, the Nordic countries should improve knowledge of CRM availability, develop new recycling strategies, support demonstration and selected R&D actions, and strengthen Nordic influence on the development of European legislation and standards.
Using PageRank in Feature Selection

Feature selection is an important task in data mining because it allows to reduce the data dimensionality and eliminates the noisy variables. Traditionally, feature selection has been applied in supervised scenarios rather than in unsupervised ones. Nowadays, the amount of unsupervised data available on the web is huge, thus motivating an increasing interest in feature selection for unsupervised data. In this paper we present some results in the domain of document categorization. We use the well-known PageRank algorithm to perform a random-walk through the feature space of the documents. This allows to rank and subsequently choose those features that better represent the data set. When compared with previous work based on information gain, our method allows classifiers to obtain good accuracy especially when few features are retained.
Risk Assessment to the Health of Amazonian Indigenous For the Consumption of Fish, Meat of Hunts and Vegetables Containing Metylmercury

This study was to evaluate the exposure to methylmercury (HgMe) and the potential health risk of Tupari Indians through the consumption of their main foods. Were collection of samples of plant foods and muscle tissue from different species of fish and wild animals consumed in three villages of the Rio Branco Indigenous Land in Rondonia, in the Brazilian Amazon. The HgMe was measured in an atomic fluorescence spectrophotometer with gas chromatography. The statistical treatment of the data was performed by software R. Of the six different plant species, only sweet potato (Ipomoea batatas) had mean concentrations of HgMe above the limit of detection of the analytical technique for the three villages. There was a significant difference in the levels of HgMe between the species of wild animals and fish belonging to the same alimentary habit. Carnivores presented higher levels of HgMe than those obtained for non-predators, both for fish and for wild animals. The results of the assessment of the potential risk to indigenous health indicated a total HgMe of the weekly ingestion rate (WIR) of between 8.4 and 15.0 μg / kg of body weight for the villages evaluated, extrapolating all reference doses ( RfD) regarding for the Provisional Tolerable Weekly Intake (PTWI). The risk quotients (RQ) varied from 5.3 to 21.4, considerably exceeding the limit (RQ ≤ 1), which allows to consider the impossibility of toxic effects of HgMe. The fishes accounted for the highest percentage of WIR of HgMe for all villages, with an emphasis on predatory species. Considering the nutritional value of fish meat, it is suggested the continuity of the consumption of this meat in the villages with preference for non-carnivores.
Unsupervised Dialogue Act Induction using Gaussian Mixtures

This paper introduces a new unsupervised approach for dialogue act induction. Given the sequence of dialogue utterances, the task is to assign them the labels representing their function in the dialogue. Utterances are represented as real-valued vectors encoding their meaning. We model the dialogue as Hidden Markov model with emission probabilities estimated by Gaussian mixtures. We use Gibbs sampling for posterior inference. We present the results on the standard Switchboard-DAMSL corpus. Our algorithm achieves promising results compared with strong supervised baselines and outperforms other unsupervised algorithms.
Global modeling of transcriptional responses in interaction networks

MOTIVATION Cell-biological processes are regulated through a complex network of interactions between genes and their products. The processes, their activating conditions and the associated transcriptional responses are often unknown. Organism-wide modeling of network activation can reveal unique and shared mechanisms between tissues, and potentially as yet unknown processes. The same method can also be applied to cell-biological conditions in one or more tissues. RESULTS We introduce a novel approach for organism-wide discovery and analysis of transcriptional responses in interaction networks. The method searches for local, connected regions in a network that exhibit coordinated transcriptional response in a subset of tissues. Known interactions between genes are used to limit the search space and to guide the analysis. Validation on a human pathway network reveals physiologically coherent responses, functional relatedness between tissues and coordinated, context-specific regulation of the genes. AVAILABILITY Implementation is freely available in R and Matlab at http://www.cis. hut.fi/projects/mi/software/NetResponse
Echo of the Younger Dryas in Holocene Lake Sediments on the Tibetan Plateau

Reading the sediment record in terms of past climates is challenging since linking climate change to the associated responses of sedimentary systems is not always straightforward. Here we analyze the erosional response of landscapes on the Tibetan Plateau to interglacial climate forcing. Using the theory of dynamical systems on Holocene time series of geochemical proxies, we derive a sedimentary response model that accurately simulates observed proxy variation in three lake records. The model suggests that millennial variations in sediment composition reflect a self‐organization of landscapes in response to abrupt climate change between 11.6 and 11.9 ka BP. The self‐organization is characterized by oscillations in sediment supply emerging from a feedback between physical and chemical erosion processes, with estimated response times between 3,000 to 18,000 years depending on catchment topography. The implications of our findings emphasize the need for landscape response models to decipher the paleoclimatic code in continental sediment records.
Seasonal Drought Prediction: Advances, Challenges, and Future Prospects

Drought prediction is of critical importance to early warning for drought managements. This review provides a synthesis of drought prediction based on statistical, dynamical, and hybrid methods. Statistical drought prediction is achieved by modeling the relationship between drought indices of interest and a suite of potential predictors, including large‐scale climate indices, local climate variables, and land initial conditions. Dynamical meteorological drought prediction relies on seasonal climate forecast from general circulation models (GCMs), which can be employed to drive hydrological models for agricultural and hydrological drought prediction with the predictability determined by both climate forcings and initial conditions. Challenges still exist in drought prediction at long lead time and under a changing environment resulting from natural and anthropogenic factors. Future research prospects to improve drought prediction include, but are not limited to, high‐quality data assimilation, improved model development with key processes related to drought occurrence, optimal ensemble forecast to select or weight ensembles, and hybrid drought prediction to merge statistical and dynamical forecasts.
Complexity of Planning with Partial Observability

We show that for conditional planning with partial observability the problem of testing existence of plans with success probability 1 is 2-EXP-complete. This result completes the complexity picture for non-probabilistic propositional planning. We also give new proofs for the EXP-hardness of conditional planning with full observability and the EXPSPACE-hardness of conditional planning without observability. The proofs demonstrate how lack of full observability allows the encoding of exponential space Turing machines in the planning problem, and how the necessity to have branching in plans corresponds to the move to a complexity class defined in terms of alternation from the corresponding deterministic complexity class. Lack of full observability necessitates the use of beliefs states, the number of which is exponential in the number of states, and alternation corresponds to the choices a branching plan can make.
Numerical Analysis of Flow past Circular Cylinder with Triangular and Rectangular Wake Splitter

In the present work flow past circular cylinder and cylinder with rectangular and triangular wake splitter is studied to improve aerodynamic parameters. The Comparison of drag coefficient is tabulated for bare cylinder, cylinder with rectangular and triangular wake splitters. Flow past circular cylinder and cylinder with triangular and rectangular wake splitter is performed at Reynoldsnumber 5, 20, 40, 50,80, 100.An incompressible PISO finite volume code employing a non-staggered grid arrangement is used, a second order upwind scheme is used for convective terms. The time discretization is implicit and a Second order Crank-Nicholson scheme is employed. Length of wake splitter in both configurations is taken to be equal to diameter of cylinder. Wake length is found to be less with rectangular wake splitter when compared to bare cylinder and cylinder with triangular wake splitter. Coefficient of drag is found to be less for triangular wake splitter when compared to bare cylinder & cylinder with rectangular wake splitter. Keywords—Coefficient of drag and pressure, CFDFLUENT,Triangular and rectangular wake splitter,wake length.
Understanding the Value of Tank Ecosystem A Case Study of Tank in Singanallur, Noyyal Basin

Wetlands, in particular tank ecosystem, produce numerous benefits that are valued by the stakeholders. Despite the importance, the services are being used as free and infinite as most of them are non-marketed and are undervalued. There prevails increasing interest for concepts of ecosystem services and valuation of such services in recent years. This makes the policy makers to consider all the aspects and work on policies so as to enhance the optimal usage of services and conservation of ecosystem. The purpose of this study is to elucidate the value of Singanallur tank in Noyyal basin, providing provisioning and recreational services by employing valuation methods like market price method, contingent valuation and individual travel cost method and each attributes of the tanks are quantified in monetary terms. The total value of Singanallur tank is Rs. 7.2 million per year.
The Dunning-Kruger Effect and SIUC University's Aviation Students

This paper describes a two-part study on the Dunning-Kruger effect in SIUC University’s aviation students. The Dunning-Kruger effect indicates that individuals with lower skill or knowledge levels have unrealistic positive images of their capabilities compared to their peers. Results indicate that the Dunning-Kruger effect is present in SIUC aviation students. Students scoring lower on both a grammar test and a pilot knowledge test grossly overestimated their ability, while higher scoring students underestimated their ability. Additional research using other pilot training programs and other aviation industry safety personnel should be undertaken before any generalizations can be made. However, this study indicates that the Dunning-Kruger effect might be a problem within the aviation industry and could play a role in the safety of the National Airspace System.
Behavioral Changes in Patients with Multiple Sclerosis

Background Behavioral changes are common in patients with multiple sclerosis (MS), however not as readily recognized as cognitive impairments. Objective The aim of this study was to analyze behavioral changes and its relation to disease characteristics, disability, and cognitive impairments in patients with MS. Method This is a single-center cross-sectional study. A detailed neuropsychological examination, including the Frontal Systems Behavior Scale (FrSBe), the Beck depression inventory (BDI), and the Wuerzburg Fatigue Inventory for Multiple Sclerosis (WEIMuS) test, was performed. FrSBe results were correlated with disease characteristics, disability, and cognitive assessments. Results 66 patients were enrolled (mean age: 43.4 years; disease duration: 9.3 years; Expanded Disability Status Scale: 3.0). Up to one third of patients showed behavioral changes in at least one domain or the total score of the FrSBe. Patients were mildly affected with regard to cognitive functioning. Consistent correlation was found between behavioral changes and fatigue (WEIMuS) and depressive symptoms (BDI), but not with disease characteristics, disability, or cognitive functions. There was an increase of behavioral changes on all FrSBe scales in the current status compared to the retrospectively rated status before disease onset. Self- and family ratings with regard to current behavioral changes were similar. Conclusion Behavioral changes are common in otherwise mildly affected MS patients with up to one third being affected. In this patient cohort, behavioral changes occur largely independent of disease characteristics, physical disability, and cognitive functioning but correlate with both fatigue and depressive symptoms. Therefore, they should be tested specifically.
Intelligent feature extraction for ensemble of classifiers

This paper presents a two-level approach to create ensemble of classifiers based on intelligent feature extraction and multi-objective genetic optimization. The first stage optimizes a set of representations, which is used to create classifiers. The second stage then optimizes the ensemble's aggregated classifiers. To assess the approach's feasibility, a set of tests with isolated handwritten digits is performed. The experimental results encourage further researches in this direction, as the optimized ensemble of classifiers outperforms the single classifier approach.
Homozygous Deletion of MTAP Gene as a Poor Prognosticator in Gastrointestinal Stromal Tumors

Purpose: Chromosome 9 is frequently deleted in high-risk gastrointestinal stromal tumors (GISTs), whereas its specific tumor suppressor genes (TSGs) are less understood. We did an integrative study of MTAP gene at 9p21 to analyze its implication in GISTs. Experimental Design: To search TSGs on chromosome 9, we used ultrahigh-resolution array comparative genomic hybridization to profile DNA copy number alterations of 22 GISTs, with special attention to MTAP gene. MTAP immunoexpression was assessable for 306 independent GISTs on tissue microarrays, with 146 cases analyzed for MTAP homozygous deletion, 181 for mutations of KIT and PDGFRA receptor tyrosine kinase genes, and 7 for MTAP hypermethylation. Results: Array comparative genomic hybridization identified 11 candidate TSGs on 9p and six on 9q. MTAP and/or CDKN2A/CDKN2B at 9p21.3 were deleted in one intermediate-risk (11) and seven high-risk (70) GISTs with two cases homozygously codeleted at both loci. MTAP homozygous deletion, present in 25 of 146 cases, was highly associated with larger size and higher mitotic rate, Ki-67 index, and risk level (all P < 0.01) but not with receptor tyrosine kinase genotypes. Whereas MTAP homozygous deletion correlated with MTAP protein loss (P < 0.001), 7 of 30 GISTs without MTAP expression did not show homozygous deletion, including three MTAP-hypermethylated cases. MTAP homozygous deletion was univariately predictive of decreased disease-free survival (P < 0.0001) and remained multivariately independent (P = 0.0369, hazard ratio = 2.166), together with high-risk category (P < 0.0001), Ki-67 index >5 (P = 0.0106), and nongastric location (P = 0.0416). Conclusions:MTAP homozygous deletion, the predominant mechanism to deplete protein expression, is present in 17 of GISTs. It correlates with important prognosticators and independently predicts worse outcomes, highlighting the role in disease progression. (Clin Cancer Res 2009;15(22):696372)
Forkhead Transcription Factor FOXO3a Is a Negative Regulator of Angiogenic Immediate Early Gene CYR61, Leading to Inhibition of Vascular Smooth Muscle Cell Proliferation and Neointimal Hyperplasia

Cysteine-rich angiogenic protein 61 (CYR61, CCN1) is an immediate early gene expressed in vascular smooth muscle cells (VSMCs) on growth factor stimulation, and its expression has been suggested to be associated with postangioplasty restenosis. The forkhead transcription factors are reported to play various roles in cellular proliferation, apoptosis, and even adaptation to cellular stress. We hypothesized that the forkhead transcription factor FOXO3a may regulate CYR61 expression in VSMCs and investigated the CYR61-modulating effect of FOXO3a in the process of vascular response to vasoactive signals and vascular injury. To evaluate the effect of FOXO3a on CYR61 expression, rat VSMCs were infected with adenoviral vectors expressing constitutively active FOXO3a (Ad-TM-FOXO3a). Constitutively active FOXO3a gene transduction suppressed CYR61 expression. Luciferase assay with the deletion constructs of the forkhead factor binding motif in CYR61 promoter region, which resulted in a significant decrease in luciferase expression compared with the intact construct, and chromatin immunoprecipitation analysis confirmed transcriptional regulation of CYR61 by FOXO3a. Serum and angiotensin II rapidly induced CYR61 expression, which was significantly reduced by Ad-TM-FOXO3a. Reduction of VSMC proliferation and migration associated with FOXO3a activation was significantly reversed by cotransfection of adenoviral vector expressing CYR61, whereas apoptosis induction by FOXO3a was not influenced. In a rat balloon carotid arterial injury model, CYR61 was rapidly induced in VSMCs in the early stage of injury and remained elevated until 14 days, which was suppressed by Ad-TM-FOXO3a transfection. After 14 days, there was a significant reduction in neointima by FOXO3a transduction compared with the control group (0.06±0.02 versus 0.20±0.07 mm2, P<0.01). Such reduction of neointimal hyperplasia by Ad-TM-FOXO3a was reversed by CYR61 replenishment. These data suggest that FOXO3a is a negative transcription factor of CYR61 and that suppression of CYR61 is among several mechanisms by which FOXO3a inhibits VSMC proliferation and neointimal hyperplasia.