Miracle-dz/UniFAR-FTUs huggingface dataset:
CAPITAL STRUCTURE AND PROFITABILITY OF LARGE-SCALE RETAIL SUPERMARKETS IN KENYA

Capital structure decisions ensure that supermarket managers stipulate optimum capital structure for the organization. Despite the implementation of capital structure decisions, poor financial performance has plagued most of large-scale retailers for the past 20 years, forcing some to close some of its outlets. Uchumi supermarket, Tuskys supermarkets among other supermarkets have been making heavy losses leading to the closure of some of their branches. Uchumi has closed 3 5(95%) branches, Tuskys 61(95.3%) branches, and Choppies 13(87%) branches. According to an external audit report in 2020, Nakumatt owed creditors Ksh.38 billion yet the company gave over Ksh. 1 billion as interest-free soft loans to its directors. The objective of this study is to assess the effect of capital structure decisions on the profitability of large-scale retail supermarkets in Kenya. The study was anchored on the pecking order theory. The study employed a cross-sectional research design. A census sampling technique was employed where all the selected supermarkets were considered. Secondary data was collected from audited financial statements. Panel data was analyzed using descriptive and inferential statistics. Descriptive statistics comprised of minimum values, maximum values, mean and standard deviation and inferential statistics consisted of correlational analysis and random effects models. The study findings indicated that capital structure decisions have a negative and statistically significant effect on the profitability of large-scale retail supermarkets in Kenya. This is supported by a regression coefficient of –0.3479 and a p-value of 0.000. The study suggested that the management of retail stores should balance between debt and equity financing to ensure an optimum capital structure that maximizes profitability. JEL: O10; O12; L81 Article visualizations:
HEXACO personality domains and deviant behavior in Nigerian public universities

Workplace deviance is one of the significant problems in Nigerian public universities. This study aims to investigate the impact of HEXACO personality factors (honesty-humility, emotionality, and agreeableness (H-HEA)) on deviant workplace behavior in public universities in Southwestern Nigeria. The choice of the institutions (Ekiti State University, University of Lagos, and the Federal University of Akure) in the Southwestern region was based on purposive sampling. Simple random sampling was employed to select academic and non-academic staff. The study adopted a quantitative research design and employed Pearson correlation and multiple regression analysis to analyze and test the hypotheses. The findings revealed that the H-HEA domain of personality traits negatively correlates with organizational and interpersonal deviance. Secondly, H-HEA personality traits have a negative effect on organizational and interpersonal deviance. Overall, the results of the regression analyses suggest that the H-HEA HEXACO domains of personality traits individually reduces the organizational and interpersonal forms of deviance. Based on the findings, the human resource departments of these institutions can curb workplace deviance by giving preference to candidates or individuals with high scores in H-HAE personality traits. This will go a long way in curtailing the vices of workplace deviance in Southwestern Nigeria public universities.
Is depressed mood clinically relevant at the onset of schizophrenia? A longitudinal study.

The aims of this investigation were: (1) to calculate baseline prevalence of FES patients with relevant depressed mood (DM), (2) to longitudinally monitor DM levels over a 12-month follow-up, and (3) to investigate their associations with clinical data and the specific treatment components of an “Early Intervention in Psychosis” (EIP) program.The Positive And Negative Syndrome Scale (PANSS) was completed by all FES participant. Individuals with a baseline PANSS “Depression” item subscore of ≥ 5 were classified as having relevant depressed mood (FES/DM+). Chi-square and Mann-Whitney tests were used for inter-group comparisons. A linear regression analysis was also performed.Fifty-three (33.3%) participants were in the FES/DM+ subgroup. Relevant baseline DM at baseline was associated with female gender and a higher PANSS “Positive Symptoms” score. Across the follow-up, FES individuals improved their DM levels. This was significantly related to a longitudinal decrease in PANSS “Positive Symptoms” levels.More than 1/3 of FES subjects had relevant DM already at the recruitment time in an EIP service. This suggests that relevant depression in FES subjects is usually under-treated. Moreover, we observed a significant decrease in DM severity levels across the follow-up. This decrease was associated with the longitudinal severity reduction in positive symptom levels, reflecting their state-related fluctuations.DM is relatively frequent in FES, already at the recruitment in EIP services. However, its severity decreases overtime within specialized EIP programs.
Multivariate adaptive warped kernel estimation

We deal with the problem of nonparametric estimation of a multivariate regression function without any assumption on the compacity of the support of the random design, thanks to a " warping " device. An adaptive warped kernel estimator is first defined in the case of known design distribution and proved to be optimal in the oracle sense. Then, a general procedure is carried out: the marginal distributions of the design are estimated by the empirical cumulative distribution functions, and the dependence structure is built using a kernel estimation of the copula density. The copula density estimator is also proved to be optimal in the oracle and in the minimax sense. The plug-in of these estimates in the regression function estimator provides a fully data-driven estimate. A numerical study illustrates the theoretical results.
Glioblastoma modeling with 3D organoids: progress and challenges

Glioblastoma (GBM) is the most aggressive adult primary brain tumor with nearly universal treatment resistance and recurrence. The mainstay of therapy remains maximal safe surgical resection followed by concurrent radiation therapy and temozolomide chemotherapy. Despite intensive investigation, alternative treatment options, such as immunotherapy or targeted molecular therapy, have yielded limited success to achieve long-term remission. This difficulty is partly due to the lack of pre-clinical models that fully recapitulate the intra- and intertumoral heterogeneity of GBM and the complex tumor microenvironment. Recently, GBM 3D organoids originating from resected patient tumors, genetic manipulation of induced pluripotent stem cell (iPSC)-derived brain organoids, and bio-printing or fusion with non-malignant tissues have emerged as novel culture systems to portray the biology of GBM. Here, we highlight several methodologies for generating GBM organoids and discuss insights gained using such organoid models compared to classic modeling approaches using cell lines and xenografts. We also outline limitations of current GBM 3D organoids, most notably the difficulty retaining the tumor microenvironment, and discuss current efforts for improvements. Finally, we propose potential applications of organoid models for a deeper mechanistic understanding of GBM and therapeutic development.
Numerical and theorical study of the blow-up profile in nonlinear parabolic equations

We are interested in finite-time blow-up phenomena arising in the study of Nonlinear Parabolic Partial Differential Equations, in particular in the blow-up profile, under the theoretical and numerical aspects. In the theoretical direction, we are interested in particular in finite-time blow-up phenomena for some class of strongly perturbed semilinear heat equations with Sobolev subcritical power nonlinearity. Working in the frameworkof similarity variables, we first derive a Lyapunov functional in similarity variables which is a crucial step to derive the blow-up rate of the solution. In a second step, we are interested in the structure of the solution near blow-uptime and point. We classify all possible asymptotic behaviors of the solution when it approaches to the singularity.Then we describe blow-up profiles corresponding to these asymptotic behaviors. In a third step, we construct for this equation a solution which blows up in finite time at only one blow-up point with a prescribed blow-up profile. The construction relies on the reduction of the problem to a finite dimensional one and the use of index theory to conclude. In the numerical direction, we intend to develop methods in order to give numerical answers to the question of the blow-up profile for some parabolic equations including the Ginzburg-Landau model. We propose two methods.The first one is the rescaling algorithm proposed by Berger and Kohn in 1988 applied to parabolic equations which are invariant under a scaling transformation. This scaling property allows us to make a zoom of the solution when it is close to the singularity, still keeping the same equation. The main advantage of this method is its ability to give a very good numerical approximation allowing to attain the numerical blow-up profile. The blow-up profile we obtain numerically is in good accordance with the theoretical one. Moreover, by applying the method to a critical nonlinear heat equation with a nonlinear gradient term, where almost nothing is known, we give a conjecture for its blow-up profile thanks to our numerical simulations. The second one is a new mesh-refinement method inspired by the rescaling algorithm of Berger and Kohn, which is applicable to more general equations, in particular those with no scaling invariance.
Stronger together: learner reactions on a team-based, interprofessional first death simulation experience

ABSTRACT Patient death is a common experience that may be traumatic for health care providers. Although current rates of burnout are high, evidence supports that interprofessional coping can improve clinician mental health. While health care simulation affords learners freedom of safety to participate in a variety of educational experiences, current application of simulation during patient death is limited to professional duties, without explicitly addressing learner emotional well-being. We designed a patient death simulation scenario within a supportive and reflective interprofessional environment to teach foundational coping and well-being strategies to preclinical nursing, medical, and pharmacy students. Sixty-one students participated in this team-based, First Death simulation experience. Debriefings were analyzed using qualitative inductive content analysis methodology. Students reacted to being part of an interprofessional team after having participated in simulation about the death of a patient as described by five categories: emotional awareness, communication insight, feeling stronger together, with role curiosity, and through reflections on support. Findings suggested that simulation is an effective teaching modality for mentoring interprofessional students on humanistic well-being strategies. Furthermore, the experience fostered reactions transcending interprofessional competencies, which are transferrable to future clinical practice.
Update on Commonly Used Molecular Typing Methods for Clostridioides difficile

This review aims to provide a comprehensive overview of the significant Clostridioides difficile molecular typing techniques currently employed in research and medical communities. The main objectives of this review are to describe the key molecular typing methods utilized in C. difficile studies and to highlight the epidemiological characteristics of the most prevalent strains on a global scale. Geographically distinct regions exhibit distinct strain types of C. difficile, with notable concordance observed among various typing methodologies. The advantages that next-generation sequencing (NGS) offers has changed epidemiology research, enabling high-resolution genomic analyses of this pathogen. NGS platforms offer an unprecedented opportunity to explore the genetic intricacies and evolutionary trajectories of C. difficile strains. It is relevant to acknowledge that novel routes of transmission are continually being unveiled and warrant further investigation, particularly in the context of zoonotic implications and environmental contamination.
Central and Class-Preserving Automorphisms of Finite p-Groups

Let G be a finite p-group and let Aut(G) denote its full automorphism group. An automorphism α of G is called a class-preserving automorphism if, for each x ∈ G, there exists an element gx ∈ G such that α(x) = g−1 x xgx; and is called an inner automorphism if, for all x ∈ G, there exists a fixed element g ∈ G such that α(x) = g−1xg. The group Inn(G) of all inner automorphisms of G is a normal subgroup of the group Autc(G) of all class-preserving automorphisms of G. We denote the group Autc(G)/ Inn(G) of all class preserving outer automorphisms by Outc(G). By Aut M N (G), we denote the set of all automorphisms of G which centralize G/M and N , where M and N are two normal subgroups of G. An automorphism α of G is called a central automorphism if g−1α(g) ∈ Z(G) for all g ∈ G. Let Autz(G) denote the group of all central automorphisms of G and let Autz(G) denote the group of all those central automorphisms which fix the center of G element-wise. The main object of the thesis is to study central and class-preserving automorphisms of a finite p-group, where p is a prime. More specifically, we study when Autz(G) = Z(Inn(G)) and when Outc(G) 6= 1. In chapter 2, we characterize all finite p-groups G of order p(n ≤ 6), where p is a prime for n ≤ 5 and an odd prime for n = 6, such that the center of the inner automorphism group of G is equal to the group of central automorphisms of G. In chapter 3, we characterize all finite p-groups of order dividing p, where p is a prime for n ≤ 6 and an odd prime for n = 7, such that Z(Inn(G)) = Autz(G) < Autz(G). In chapter 4, we give necessary and sufficient conditions on a group of order p such that G has a non-inner class-preserving automorphism. As a consequence, we give short and alternate proofs of results of Yadav [55, Section 5] and Kalra and Gumber [34, Theorem 4.2]. In chapter 5, we have decided the Hasse principle for some groups of order p, where p is an odd prime, using isoclinism families given by James [31], by giving alternate proofs of results of Narain and Karan [42] and Rai and Yadav [45]. We also classify some groups G of order p such that G admits a non-inner automorphism of order p.
Parenting styles and obsessive-compulsive symptoms in college students: the mediating role of perfectionism

Introduction Obsessive-compulsive symptoms is a common psychological phenomenon among early adulthood college students, which are closely related to their parents’ parenting styles. Theoretical and some empirical studies have suggested the mediating role of perfectionism in this process, but this has not been confirmed, and the binary perspective of positive-negative perfectionism has not been addressed in this issue. Methods This study aimed to investigate the mediating role of perfectionism in the relationship between parenting styles and obsessive-compulsive symptoms among college students. A total of 661 college students participated in this study. Results Negative perfectionism mediated the relationship between negative parenting style and obsessive-compulsive symptoms among college students. Negative parenting style predicted obsessive-compulsive symptoms through its positive predictive effect on negative perfectionism. However, the mediating effect of positive perfectionism was not significant in this process. Discussion This study provides further evidence of the mechanisms underlying the occurrence of obsessive-compulsive symptoms, and offers new ideas for interventions for OCD.
Determinants of neonatal jaundice among neonates admitted to neonatal intensive care unit in public hospitals of Sidama Region, Sidama, Ethiopia, 2022: an unmatched case-control study

Introduction neonatal jaundice appears in most neonates as “physiological jaundice” in the first few weeks of life; however, pathological jaundice is associated with an increased risk of long-term complications and mortality only a few studies have been conducted on the determinants of neonatal jaundice in Ethiopia. The aim of this study was to identify the determinants of neonatal jaundice (pathological) among neonates admitted to neonatal intensive care units in Sidama Region general and referral public hospitals. Methods a hospital-based unmatched case-control study was conducted among 270 neonates in public hospitals of Sidama Region from June 23 to August 8, 2022. We used a pre-tested interviewer-administered questionnaire and collected by open data kit (ODK) then the data was downloaded and exported to Microsoft Excel worksheets (XLS) and imported to SPSS version 26 for further analysis. Bi-variable logistic regression analysis was performed. Variables with a P-Value of less than 0.25 were included in multivariable logistic regression. Multi-variable logistic regression was performed and Adjusted Odds ratio (AOR) with a 95% confidence interval was computed and statistical significance was declared at a p-value <0.05. Results a total of 270 neonates with mothers (90 cases and 180 controls) with a response rate of 100% were included in this study. Factors significantly increased the odds of developing neonatal jaundice were multiparty (AOR=2.869(95%CI 1.426-5.769)), prolonged duration of labor (AOR=4.618(95%CI 1.689 - 12.625)). ABO incompatibility (AOR=3.362(95%CI, 1.185 - 9.537)). Preterm (AOR=2.936(95%CI, 1.2456.923)), birthasphyxia (AOR=2.278(95%CI,1.1454.531)) and polycythemia (AOR=3.397(95%CI, 1.147-10.061)). Conclusion in this study multiparty, prolonged duration labor, ABO incompatibility, preterm gestational age, birth asphyxia, and polycythemia were factors that significantly increased the odds of developing neonatal jaundice.
THE EFFECT OF HYPNOBIRTHING ON THE ANXIETY LEVEL OF PREGNANT WOMEN IN TRIMESTER III IN THE WORKING AREA OF THE PROUDE I HEALTH CENTER, PROUDE DISTRICT, MAJENE

Every pregnant woman will experience physical and psychological changes that can trigger anxiety in the mother. Anxiety that occurs in third trimester pregnant women if not handled properly can have a negative impact on both the mother and the fetus. Hypnobirthing is a technique that can reduce anxiety in pregnant women. This study aims to determine the effect of hypnobirthing on the anxiety level of pregnant women in the third trimester in the work area of the Banggae I Health Center. This type of research is Quasy Experimental with a pretest and posttest control group design. This research was conducted at the Banggae I Public Health Center, Banggae sub-district. A sample of 30 pregnant women in the third trimester who met the inclusion criteria using the accidental sampling method, the independent variable of this study was hypnobirthing and the dependent variable was the level of anxiety of pregnant women in the third trimester and used the HARS questionnaire as an anxiety measure. The data analysis technique used the Wilcoxon test with the SPSS program. From the results of the Wilcoxon test, all pregnant women experienced a decrease in anxiety after being given treatment in the form of Hypnobirthing with a p value of 0.01 smaller than 0.05 so it was said that there was an effect of Hypnobirthing on the anxiety level of third trimester pregnant women. Proud I, Banggae Sub-district, Majene Regency in 2022.
Holocene relationships between climate, waterfowl, and lacustrine nutrient cycling at Kettle Lake, North Dakota, USA

Avian populations can substantially influence lacustrine nutrient loading and biogeochemical cycling through guano deposition. Here, we examine the influence of climate-forced avian migration throughout the Holocene on Kettle Lake, North Dakota, using stable nitrogen and carbon isotope values (δ15N, δ13C) of lake sediment organic matter. Carbon content and δ13C values are negatively correlated with δ15N and appear to be driven by changes in charcoal abundance and watershed vegetation, respectively. We find enriched δ15N values when the guano mineral struvite is present in the lake sediment core in the early to Mid-Holocene. A strong δ15N-percent Nitrogen content relationship during periods with struvite, relative to periods without struvite, indicates that guano deposition from mass bird visitations altered past nitrogen cycle processes, likely through enhanced denitrification. These results attest to the ability of waterfowl to alter lacustrine N-cycling in a mid-continental North American lake, and indicate that paleo-N data in this particular lake are recording a unique history that does not necessarily represent regional paleoenvironmental conditions. However, a significant, positive relationship between δ15N and Ambrosia and Amaranthaceae pollen abundance suggests avian visitation and its impacts on the N-cycle occurred during periods of anomalously wet summers superimposed on the background conditions of early to Mid-Holocene drought.
A Comparative Study of Numerous Antioxidants Supplementation on Several Characteristics for Cooled Storage of Awassi Rams Epididymal Sperms

T HE study was conducted to investigated effect of three amino-acids which were Methionine (0.2 Mm), L-Arginine (0.4 Mm) and D-Alanine (15 Mm) on Awassi Epididymal sperms characteristics after storage at 4 o C. Twenty five pairs of testicles (n=25, 50 testis/semen samples) from 25 mature Awassi Rams aged between 1-4 years were used in present study. Epididymal sperms were collecting by slicing and squeeze of epididymis and diluted in egg yolk extender. Four test tubes samples were created, each of which contained an equal amount of penicillin and streptomycin as 100.000 IU and 100 mg, respectively, fructose, one kind of amino acid, sodium citrate, and egg yolk. The fourth test tube left as control group with no adding of amino acid and all test tubes kept in refrigerator temperature at 4 o C. The results show that after 24,27 hours of storage, Methionine improve significantly p<0.05 sperm individual motility which were 72.6±2.9%, 57.5±3.2%, respectively, sperm live percentage was 73.6±2.3%, 53.2±2.8%, respectively, Sperm abnormalities was 3.0± 0.1, 7.2±0.1%, respectively. In present study, data recorded of sperm characteristics after adding methionine were eminent on that sperms values were recorded after adding arginine and methionine. In conclusion Methionine at dose 0.2 Mm had superior effect on epididymal sperm characteristics after storage at 4 o C for 72 hours in cooling method, however; Arginine (0.4 Mm) and Alanine (15 Mm) also act to improve sperm characteristics when compare with control group in Awassi rams epididymal sperms.