Miracle-dz/UniFAR-FTUs huggingface dataset:
The Effect of an Educational Intervention for Improving Mothersâ€™ Care for their Children with Cerebral Palsy

Cerebral palsy is a group of permanent disorders of movement and posture results from brain damage originating early in life and causes activity limitation, sensory, cognitive, communicative and behavioral problems in children. Nurses have an important role in providing support and ongoing education to the children with cerebral palsy and their parents especially the mothers who are the primary caregivers for their children and also, provide them with adequate knowledge and training about the skills of daily living according to their childrenâ€™s functional level. Aim: Evaluate the effect of an educational intervention for improving mothersâ€™ care for their children with cerebral palsy. Method: A quasi- experimental design was used to conduct this study, including 65 mothers having children with cerebral palsy. The tools of data collection were a structured questionnaire sheet and observation checklists. Results: The results of this study clarified that, the majority of the studied mothers had unsatisfactory knowledge before the teaching program while, all of them had satisfactory knowledge about cerebral palsy and care of associated problems in their children after 6 months of the educational program. Also, more than half of the studied mothers had unsatisfactory reported practices before the educational program while, more than two thirds had satisfactory reported practices regarding daily care of their children with cerebral palsy after 6 months of the educational program. In addition, half of the studied mothers had a satisfactory observed practices before the teaching program while, the majority of them had satisfactory observed practices post 6 months of the educational program. There was a statistical significant difference between the total knowledge score and the total practices score of the studied mothers regarding care of children with cerebral palsy. Conclusion: based on the results of the present study and research hypothesis, it is concluded that, the educational program was an effective in improving mothers care for their children with cerebral palsy. Recommendations: Continuous educational programs should be provided for all mothers of children with cerebral palsy about the disease and daily care of their children in all health care settings by qualified and trained nurses.
COMPARATIVE EVALUATION OF SURFACE ROUGHNESS CAUSED BY BEVERAGES ON WHITE SPOTLESION TREATED WITH RESIN INFILTRATE: AN- IN VITRO STUDY

1Department of Pedodontics and Preventive Dentistry, Rajah Muthaih Dental College and Hospital, Annamalai University, India 2Department of Conservative Dentistry and Endodontics, Government Dental College and Hospital, Hyderabad, India 3Department of Pedodontics and Preventive Dentistry, AIMST University, Malaysia 4Department of Conservative dentistry and Endodontics, AIMST University, Malaysia 5Department of Oral and Maxillofacial Surgery, India 6NIPER, Ahmedabad, India
DRUG ENHANCEMENT, SYNERGISM AND ANTIFUNGAL ACTIVITY OF MICONAZOLE ASSOCIATED POLYGODIAL AGAINST CANDIDA ALBICANS

Miconazole has low toxicity, however, there is a high incidence resistance of Candida sp. In the search for new drugs or improve existing ones, the originating products of medicinal plants has been the target of constant studies. The aim of this work was to verifyin vitrosynergism and antifungal activity of miconazole associated with poligodial. Miconazole (MCZ) and Poligodial (P) were dissolved in dimethylsulfoxide (DMSO) 1% done successive dilutions of each product ranging from 25mg to 0,19mg/mL (Polygodial)(10 -1 to 10 -9 mg / ml); 14mg to 0,10mg/mL (miconazole). Antifungal test were based by CLSI diffusion agar against C. albicans (ATCC 18804), C. albicans (LMB01) and C. albicans (LMB02), C. tropicalis (ATCC 18807), C. lusitaniae (ATCC 42720), C. krusei (ATCC 20405). The results had shown all compounds that were effective in inhibiting Candida species. However, the zones of inhibition in agar diffusion test were higher for Miconazole (16,83mm) and Polygodial (15,16mm) while the MIX showed lower inhibition zones (14,43mm) when compared with controls. MIX was more effective in MIC test, and lowest concentration were at 10 -6 dilution (0,60mg / ml) compared to MCZ and P controls.
Disease Patterns and Drugs Load of the ICU Patients in a Tertiary Level Teaching Hospital

Objective: The objective of the present study was to investigate the disease pattern and drugs load of the ICU patients at a tertiary level teaching hospital in Mymensingh. Methods and Materials: It was a descriptive type of observational study conducted in the intensive care unit of Mymensingh Medical College Hospital, Mymensingh during the period of June 2016 to December 2016. Purposive sampling was adopted for collecting data. All the admitted ICU patients were included in this study. The study was approved by the institutional ethical committee. Results: Most of the patients in the ICU belonged to the elder age group >60 years and male patients were predominant than the female ones. Average duration of stay in ICU was 4.35 days. Admissions with respiratory system disorders were more common in ICU and in the present study it revealed that 31.68% of the reported cases belonged to respiratory problems. Average number of drugs per prescription was 6.46. Average number of anti-microbial drugs per prescription was 1.38. Conclusion: Respiratory system related admissions were common in ICU. The average number of drugs per prescription was less than the other studies. Prescription protocols need to be addressed to guide appropriate use of drugs in the ICU setting.
Frequency Of GSTP1 (Ile105Val) Gene Polymorphism In Iraqi CML Patients And Its Association With Susceptibility To CML

Glutathione S transferase pi class (GSTPs), are dimeric phase II enzymes, and one of the most important cellular detoxification systems. They play several biological roles, including protection of cellular DNA against oxidative damage that can promote carcinogenesis; hence, their activity may alter cancer risk. A growing body of evidence has revealed a potential relevance between functional polymorphisms within gene encoding for GSTs л, and susceptibility to chronic myeloid leukemia. The lack of conclusive data has prompted our research aimed at evaluating the frequency of Glutathione S transferase P1 (Ile105Val) gene polymorphism in Iraqi chronic myeloid leukaemia patients and its association with susceptibility to CML. We conducted a case-control study on 40 adult ph-positive CML patients, in addition to 40 apparently healthy sex and age matched individuals serving as control group. ‘PCR-Restriction fragment length polymorphism’ technique was emplemented to detect (Ile105Val) polymorphism. Our results revealed more than threefold higher CML risk among subjects exhibiting the variant genotype (P=0.014; OR= 3.095). Thus indicating that (Ile-105-Val) polymorphic variants of GSTP1 gene might confer a higher risk of CML development.
Hyperchloremia and Its Association with Outcomes in Critically Ill Children

To determine the relationship of hyperchloremia on development of Acute Kidney Injury (AKI), hyperchloremic metabolic acidosis, PICU length of stay and mortality in critically ill children. We did retrospective review of medical records of all children (aged 1 month to 16 years) admitted in our PICU from January to December 2015. Study population was divided into groups based on Chloride (Cl) level. Children with Cl level >110 meq/L were labelled as hyperchloremic groups and those with <110 as normochloremic group. Patients having acute kidney injury on admission and length of PICU stay <24 hours were excluded. A total 200 patients were identified, 100 in each group. Mean age was 55.59 ± 57.77 months with no difference between the two groups (p 0.66). 63% were males. Mechanical ventilation was needed in 50% patients, inotropes in 21.6 and renal replacement therapy in 14%. There was no significant difference between the two groups in development of AKI, length of PICU stay or survival (p value >0.05).
The bunionette deformity—evaluation and management

Bunionette refers to a painful prominence of the lateral eminence of the fifth metatarsal head. Evaluation consists of careful physical and radiographic examination, focusing on the nature of the deformity as well as other concomitant foot and ankle pathology. Many patients may be managed conservatively with shoe modification alone. However, in some cases this is not successful and surgical intervention may be considered. Successful surgical outcome is strongly tied to correct assessment of the deformity. A variety of surgical techniques have been described, ranging from proximal 5th metatarsal osteotomies to exostectomy. The aim of this article is to provide an overview or evaluation and management of this common deformity.
PREVALENCE OF UNDERWEIGHT AND WASTING AMONG 3-6 YEAR OLD CHILDREN IN EAST MIDNAPORE, WEST BENGAL, INDIA

Background: A widely accepted assumption is that childhood experiences set the stage for lifetime experiences.Nutrition is one of the most important factors, which influences human growth. The monitoring of children’s nutritional status is a fundamental tool for the evaluation of their health conditions and a unique opportunity for obtaining objective measures for the health assessment of a population. One of the major health problems in many developing countries including India is widespread prevalence of under nutrition among pre-school children. In India, approximately 60 million children are underweight (ACC/SCN, 2004). The Integrated Child Development Service (ICDS) program, which now covers almost all development blocks in India, is potentially well-poised to address some of the underlying causes of present undernutrition.
EARLY ORAL INTAKE POST GASTRIC SURGERY

Background: (TOF) or start early oral feeding (EOF) which seems to be safe and beneficial with promising results. Aim of study surgeries. teaching Center for two years and 4 months in which 67 patients divided into 2 groups (36 start oral feeding early and 31 wit ,nausea, vomiting, tolerance of oral intake, fever and ileus were observed and the incidence of re admission and complications were recorded. gender, with surgeon preference toward traditional late oral feeding after open surgery; there are significant difference in terms of NG tube removal ,start of oral feeding, ileus and hospital stay and passage of gas while no differen hospital re admission. postoperative ileus with short hospital stay and can be applied safely for patients with upper gastrointestinal surgery.
Study of the Diagnostic Value of Anti MCV and MMP3 Biomarkers in Serum and Synovial Fluid of Rheumatoid Arthritis Patients

Background: Rheumatoid arthritis (RA) is a systemic autoimmune disease characterized by persistent joint inflammation, damage and loss of function.Osteoarthritis (OA) is a common progressive degenerative disease that affects the joint cartilage, subchondral bone, synovial and joint capsule resulting in disability. Early diagnosis of RA is an important challenge for clinical rheumatologists as it leads to a better disease outcome. Anti-mutated citrullinated vimentin(Anti-MCV) antibodies are member of ACPAs family, that result due to antibody production against antigens produced from the mutant citrullinated vimentin. The Matrix metalloproteinase-3(MMP-3) or stromelycin-1 is a photolytic enzyme which play a pivotal role in joint. It is secreted by fibroblasts, synovial cells, and chondrocytes and is responsible for cartilage degradation. So we aimedto investigate the immunopathological and inflammatory or degenerative roles of Anti-MCV and MMP-3 in serum and synovial fluid (SF) of RA versusosteoarthritis (OA) patients.Patient and method: A total of 20 patients with RA, 20 patients with OA, and 10 control blood donors were included in the present study. CBC, ESR, CRP, RF, anti-MCV, and MMP3 were estimated in the blood of all subjects. In addition, synovial CRP, RF, Anti-MCV and MMP3 were estimated in both RA and OA patients.Results: The mean of ESR and both serum and SF CRP, RF, anti-MCV and MMP3 were significantly higher in RA group than OA group. In RA group, there was a significant positive correlation between serum anti-MCV and ESR, DAS28, serum of each of CRP, RF & MMP3 and synovial fluid anti-MCV, also, between serum MMP3 and serum anti-MCV and ESR. The sensitivity and specificity were found (75%, 80%), (95%, 90%) and (90%, 90%) for RF, anti-MCV and MMP3 respectively.Conclusion:Anti-MCV might be of a better diagnostic value for the early diagnosis of RA and its activity than RF, for its higher sensitivity and specificity detecting more aggressive and erosive disease. The elevated MMP-3 levels reflect disease activity and can be used as a specific degenerative marker for joints damage and deformity in both diseases, while more in RA than OA.
The brain renin-angiotensin system in metabolic and cardiovascular regulation

Leptin contributes to the control of resting metabolic rate (RMR) and blood pressure (BP). The renin-angiotensin system (RAS) and angiotensin AT1 receptors within the brain are also involved in the control of these processes. Here, we demonstrate the selective requirement of the AT1A receptor for RMR control by leptin. Mice lacking the AT1A receptor specifically from leptin receptor (LepR)-expressing cells (AT1A) failed to increase RMR with high fat diet and DOCA-salt treatments, but BP control remained intact. Cellular coexpression of AT1A and LepR is almost exclusive to the arcuate nucleus (ARC), primarily within agouti-related peptide (AgRP) expressing neurons. We conclude that angiotensin activates divergent mechanisms to control BP and RMR, and that the brain RAS – acting at leptin-sensitive AgRP cells of the ARC – functions as a major integrator for RMR control. Introduction The renin-angiotensin system (RAS) is well-established for its role in blood pressure (BP) and fluid balance control. In addition to the circulating RAS, the local brain RAS has been implicated in cardiovascular control, and all components of the RAS signaling cascade have been documented in the brain.
Response of Market Returns to Inflation News: Asymmetry Based on the Level of Inflation

Using daily data we look at S&P500 returns to inflation news during the period 1980-2002, where we categorize the data into sub-periods based on the level of inflation and the phase of economic cycle. We find that although stock market’s reaction to inflation news is generally negative, the response appears to depend on the level of prevailing inflation and phase of the business cycle. Specifically, we find that on the day of inflation announcement daily returns during periods of low inflation and low risks of recession respond positively to inflation news in recessionary states. Our results show that while high inflation weighs on market returns, low inflation creates positive returns opportunities when the economy faces low risks of recession. Asymmetric response of daily returns to inflation news depending on the level of inflation is an interesting novel finding.
EFFECT OF VERMICOMPOST TREATMENTS AND EM1 ON ONION WHITE ROT DISEASE

Effects of vermicompost, Effective microorganisms (EM1) and the combination between vercompost and EM1 were applied to manage white rot of onion caused by Sclerotium cepivorum Berk. under greenhouse and field trials at Mallawy Agric. Res. St., Menia Governorate. The recommended fungicide Folicure 25% EC (tebuconazole 25%) was used as comparison. All treatments under investigation either under greenhouse or field conditions reduced the percentage of infection by white rot of onion compared with untreated plants. The combination between vermicompost and EM1 under greenhouse or open field conditions was more effective in reducing the disease more than single treatments. From other hand, all treatments under investigation increased the all assessment parameters i.e., onion bulb yield, plant height, no. of leaves/plant, bulb diameter, fresh and dry bulb weight compared with untreated plants. Vermicompost treatment at the rate of 5 ton/fed combined with EM1 treatment was the best treatment for increasing onion bulb yield more than control and Folicure treatment.
EXPERIMENT AND THEORY FOR ELECTRONIC TRANSPORT PROPERTIES OF MN-BI LIQUID ALLOY

We have investigated the electrical properties of the BiMn alloy by measuring experimentally The resistivity and thermoelectric power(TEP) of liquid alloys x x 1 Mn Bi − (x=0.10, 0.20, 0.30, 0.40, 0.45). We have observed that The resistivity increases from cm ⋅ Ω μ 52 . 169 at 1050°C for pure Bismuth to cm ⋅ Ω μ 67 . 221 for the alloy; while the thermoelectric power is negative and does not present any anomalies. Experiment And Theory For Electronic Transport Properties Of Mn-Bi Liquid Alloy http://www.iaeme.com/IJMET/index.asp 1431 editor@iaeme.com In this work, we have been able to demonstrate that Manganese appears under a mixture of atoms of spin 1/2 and 3/2 states in the liquid alloy. During our resistivity calculation, x x 1 Mn Bi − was treated as a 5-components alloy, this allowed us to use an extended Faber-Ziman formalism. Mentioning that our theoretical model was based on two types of muffin tin potentials in the t-matrix, that is spin up and spin down. The resistivity is treated as the result the interferences between the two spin states of each electron with coherent and incoherent contributions. The calculated values are compared to our experimental values and give good results for x x 1 Mn Bi − alloy. Keys words: Liquid alloy; Resistivity; Bismuth; Manganese; Thermoelectric power. Cite this Article J. Ataati, A. Ben Abdellah, B. Grosdidier, J. G. Gasser and M. Mayoufi, Experiment And Theory For Electronic Transport Properties Of Mn-Bi Liquid Alloy, International Journal of Civil Engineering and Technology, 9(10), 2018, pp. (1430)-(1443). http://www.iaeme.com/IJCIET/issues.asp? JTypeIJCIET&VType=6&IType=7
Endovascular Coiling of Ruptured Subarachnoid Haemorrhage in Pregnancy: A Case Report

Subarachnoid haemorrhage (SAH) is a life-threatening type of stroke caused by bleeding into the space surrounding the brain. Here this case report explains SAH condition in pregnancy. Where this Pregnancy is a recognized risk factor for aneurysmal subarachnoid haemorrhage (SAH). However, if immediate surgical treatment is given, the prognosis is good.
Engineered Doxorubicin Delivery System Using Proteinoid-Poly (L-Lactic Acid) Polymeric Nanoparticles of Narrow Size Distribution and High Molecular Weight for Cancer Treatment

Doxorubicin (Dox), a widely used anti-cancer drug, was encapsulated within new special-tailored proteinoid nanoparticles (NPs), with the intention to overcome side effects while keeping the drug potency. The synthesis and characterization of four newly-made proteinoids of very high molecular weights (122-149 kDa) and low polydispersity (1.01-1.03) is presented. The proteinoids were synthesized from L-lysine, L-arginine, L-histidine, L-phenylalanine and poly-L-lactic acid (PLLA) segments, and are named P(KRHF-PLLA). Using this selection of amino acids provides basic positive-charged novel tailored proteinoids, with a rigid and biodegradable backbone, achieved by the incorporation of PLLA. The proteinoids self-assemble to yield NPs of a narrow-size distribution. This self-assembly procedure was utilized to encapsulate Dox within the NP core. The optimal Dox-encapsulated NPs were chosen by a study of their size, size distribution and Dox content. The chosen NPs, 15% Dox-loaded P(KRHF-PLLA) NPs were checked for their stability in different conditions. In order to improve tumor uptake and time of circulation in the blood, the chosen NPs were further PEGylated and the effects of PEGylation of the NPs, as well as the effect of the environment, on the release rate of Dox from the NPs were investigated. Additionally, the cytotoxicity of the PEGylated and non-PEGylated Dox-containing NPs was studied by XTT assay and their generation of immune-response was investigated by cytokines induction assay. Overall, the Dox-loaded NPs were found stable, non-immunogenic and showed good cell toxicity, making them good candidates to be used against cancer, while PEGylation improved all parameters. The Institute of Nanotechnology and Advanced Materials, Department of Chemistry, Bar-Ilan University, Ramat-Gan, 52900, Israel *Corresponding author Shlomo Margel, The Institute of Nanotechnology and Advanced Materials, Department of Chemistry, Bar-Ilan University, RamatGan, 52900, Israel, Tel: + 972-3-5318861, E-mail: shlomo.margel@
Optimization studies on L-asparaginase production from endophytic Bacteria

L-asparaginase is a well-recognized as amino acid degrading enzyme. It is recommended as therapeutic agent due to an antineoplastic activity. Hence, with the focus to optimize the enzyme production of a novel anticancer enzyme an attempt for the optimized production of L-asparaginase was done from the bacterial endophytes of selected medicinal plants. Total Twenty five endophytic bacteria were isolated from ethno medicinal plants specifically recommended for cancer therapy. Pure cultures of isolated bacterial endophytes were examined qualitatively and quantitatively, adopting spot inoculation and submerged fermentation respectively, for their optimum ability to produce L-asparaginase using M9medium. Out of total, 25 different isolates, 3 cultures of endophytes namely Bacillus licheniformis, Bacillus pseudomycoides & Paenibacillus denitriformis showed efficient qualitatively and quantitatively enzyme activity. The optimization studies reviled that the maximum enzyme was produced at PH.8. Temp, 40 0C, & in presence of glucose as most suitable carbon source, after incubation of 48 hrs. The substrate concentration showed direct proportional relation with an enzyme activity up to 1%w/the study indicates the bacterial endophytes as a possible source of L-asparaginase as the production strain.
Determinants of hygienic self-care practices related to skin conditions among primary school children in Harare City

In this cross-sectional study, 592 (response rate = 98.5%) primary school children selected through multi-stage sampling in the western district, Harare City responded to self-administered questionnaires measuring their reported self-care practices related to skin conditions. The prevalence of skin conditions was 8%. Associations existed between occurrence of skin conditions and sharing bath towels (p = 0.001), sharing tooth brushes (p = 0.01), and inconsistent use of shoes (p < 0.001). No association was shown between sharing clothes (p = 0.15), sharing hair combs (p = 0.07) and skin conditions. The occurrence of skin conditions decreased with age. Skin conditions are common among children and a complex chain of associations characterizes skin conditions particularly poor hygiene, poverty and overcrowding. Health promotion programmes need to focus on children to address the problem of skin conditions.