Miracle-dz/UniFAR-FTUs huggingface dataset:
Use of a Structured Method of Antimicrobial Stewardship at a City Hospital by Pharmacy Students

The objective of this study was to determine the utility of a structured method of antimicrobial stewardship by Advanced Pharmacy Practice Experience students and assess student perceptions of the tool. Pharmacy students on rotation were trained to utilize a structured team antibiotic review form (TARF) as a tool to participate in antimicrobial stewardship. Students completed anonymous evaluations regarding their confidence in performing stewardship after completing their rotation, and preceptors quantified total student interventions. Data analysis was conducted using descriptive statistics. The Fisher’s Exact Test was used to compare students’ confidence before and after using TARFs. Twenty-six students participated in antimicrobial stewardship using TARFs, resulting in 889 interventions. Nearly 96% of students reported that TARFs helped them evaluate patient antibiotics in a way that was easy to follow and that TARFs provided them with an organized and structured way to systematically evaluate antibiotics. All students felt that the TARFs increased their knowledge on how to evaluate antibiotics. Significantly more students were confident in participating in antimicrobial stewardship after using the TARF. TARF use allowed students to substantially contribute to stewardship, and provided them with a structured guide allowing for improved student knowledge and confidence.
Games and Health Education for Diabetes Control: A Systematic Review with Meta-Analysis

Finding methods to improve people’s diabetes control and management is important to prevent its complications and maintain the quality of life. The aim of this review was to assess the effect of games on the blood glucose level (glycated hemoglobin (HbA1c)). A systematic review and meta-analysis were made. Pubmed, Scopus, and CINAHL databases were consulted in July of 2020. Ten studies were selected as a final sample, most of them being clinical trials using games to improve diabetes control. Half of the studies had samples between 8 and 14.9 years old and the other half between 57 and 65 years old. The studies informed about using applications/games for mobile phones, game consoles, and board games for diabetes education and management. The meta-analysis was performed with 4 studies showing a mean difference of 0.12 (CI 95% 0.57, 0.33) of HbA1c in favor of the intervention group with p > 0.05. Games are positive for diabetes health education and promoting healthier lifestyle, but their impact on HbA1c is low.
Abundância sazonal e a composição da assembléia de peixes em duas praias estuarinas da Baía de Paranaguá, Paraná

O objetivo do presente estudo foi a caracterizacao da ictiofauna de duas praias estuarinas da Baia do Paranagua, PR. O maior numero de especies e individuos foi amostrado nos meses mais quentes, durante os quais a ocorrencia de esporadica de especies visitantes foi maior. Poucas especies estuarinas sao consideradas residentes das quais Atherinella brasiliensis Quoy & Gaimard, 1824 e Sphoeroides testudineus Linnaeus, 1758 parecem utilizar a area como bercario. Os agregados de sardinhas e anchovas ocorreram ocasionalmente em determinadas estacoes dependendo da especie, o que parece indicar um padrao de migracao das areas continentais para areas estuarinas. Esses padroes comportamentais associados com o periodo reprodutivo e de alimentacao sugerem um importante papel ecologico destas areas durante o ciclo de vida de muitas especies de peixes, principalmente quando ainda jovens.
Baseline MRI-Radiomics Can Predict Overall Survival in Non-Endemic EBV-Related Nasopharyngeal Carcinoma Patients

Simple Summary The prognostic performance of traditional methodologies in advanced nasopharyngeal carcinoma does not allow to successfully stratify patients. Previous studies showed that MRI-radiomics has been used to give additional information to improve the prognosis for this type of pathology in patients from endemic areas (Asia). The purpose of this study was to use MRI-radiomics to develop prognostic models for overall survival in patients from non-endemic areas (Europe or United States). In particular, T1-weighted and T2-weighted MRI were used for the purpose. Radiomic features from those images allowed to successfully train a prognostic signature that improved the prognostic performance of models based on clinical variables alone for different clinical endpoints (overall survival, disease-free survival and loco-regional recurrence-free survival). These results suggest how MRI-radiomics is a useful additional tool for prognosis in nasopharyngeal cancer. Abstract Advanced stage nasopharyngeal cancer (NPC) shows highly variable treatment outcomes, suggesting the need for independent prognostic factors. This study aims at developing a magnetic resonance imaging (MRI)-based radiomic signature as a prognostic marker for different clinical endpoints in NPC patients from non-endemic areas. A total 136 patients with advanced NPC and available MRI imaging (T1-weighted and T2-weighted) were selected. For each patient, 2144 radiomic features were extracted from the main tumor and largest lymph node. A multivariate Cox regression model was trained on a subset of features to obtain a radiomic signature for overall survival (OS), which was also applied for the prognosis of other clinical endpoints. Validation was performed using 10-fold cross-validation. The added prognostic value of the radiomic features to clinical features and volume was also evaluated. The radiomics-based signature had good prognostic power for OS and loco-regional recurrence-free survival (LRFS), with C-index of 0.68 and 0.72, respectively. In all the cases, the addition of radiomics to clinical features improved the prognostic performance. Radiomic features can provide independent prognostic information in NPC patients from non-endemic areas.
Chromosome reciprocal translocations have accompanied subspecies evolution in bananas

Summary Chromosome rearrangements and the way that they impact genetic differentiation and speciation have long raised questions from evolutionary biologists. They are also a major concern for breeders because of their bearing on chromosome recombination. Banana is a major crop that derives from inter(sub)specific hybridizations between various once geographically isolated Musa species and subspecies. We sequenced 155 accessions, including banana cultivars and representatives of Musa diversity, and genotyped‐by‐sequencing 1059 individuals from 11 progenies. We precisely characterized six large reciprocal translocations and showed that they emerged in different (sub)species of Musa acuminata, the main contributor to currently cultivated bananas. Most diploid and triploid cultivars analyzed were structurally heterozygous for 1 to 4 M. acuminata translocations, highlighting their complex origin. We showed that all translocations induced a recombination reduction of variable intensity and extent depending on the translocations, involving only the breakpoint regions, a chromosome arm, or an entire chromosome. The translocated chromosomes were found preferentially transmitted in many cases. We explore and discuss the possible mechanisms involved in this preferential transmission and its impact on translocation colonization.
OCCURRENCE AND MOLECULAR DETECTION OF SPIROPLASMA CITRI IN CARROTS AND ITS INSECT VECTOR, CIRCULIFER TENELLUS, IN MEXICO

In 2014, carrot plants in Zacatecas, Mexico, were found with yellow, brown, or purple-colored leaves, which were occasionally smaller and rolled. Roots of these affected plants were hairy, deformed, and small. Molecular diagnostics failed to detect phytoplasmas in these samples, but identified Spiroplasma citri in 58 and 94% of the samples using PCR targeting the spiralin and adhesion-related protein 1 (arp1) genes, respectively. Sequence analysis confirmed the presence of S. citri, and identified a novel, putative arp gene in one carrot sample. S. citri is a phytopathogenic mollicute transmitted by leafhopper species. Beet leafhoppers (Circulifer tenellus Baker) collected in the same state of Zacatecas, Mexico, were subsequently tested for S. citri infection, and 36.5% were positive using PCR targeting the arp1 gene. Sequencing analysis confirmed the presence of S. citri in the leafhoppers. This is the first report of S. citri in carrot and C. tenellus in Mexico. Previously in the Americas, S. citri in carrot was only reported in Washington and California in the United States. The presence of S. citri in carrots and the beet leafhopper in Mexico, suggests that this pathogen could become a threat to vegetable industries in this region of Mexico, including the carrot industry.
Craniofacial morphology, adaptation, and paranasal pneumatisation in Pleistocene hominins

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Gastrointestinal Applications of Iodine Quantification Using Dual-Energy CT: A Systematic Review

Dual-energy computed tomography (DECT) can estimate tissue vascularity and perfusion via iodine quantification. The aim of this systematic review was to outline current and emerging clinical applications of iodine quantification within the gastrointestinal tract using DECT. The search was conducted with three databases: EMBASE, Pubmed and The Cochrane Library. This identified 449 studies after duplicate removal. From a total of 570 selected studies, 30 studies were enrolled for the systematic review. The studies were categorized into four main topics: gastric tumors (12 studies), colorectal tumors (8 studies), Crohn’s disease (4 studies) and miscellaneous applications (6 studies). Findings included a significant difference in iodine concentration (IC) measurements in perigastric fat between T1–3 vs. T4 stage gastric cancer, poorly and well differentiated gastric and colorectal cancer, responders vs. non-responders following chemo- or chemoradiotherapy treatment among cancer patients, and a positive correlation between IC and Crohn’s disease activity. In conclusion, iodine quantification with DECT may be used preoperatively in cancer imaging as well as for monitoring treatment response. Future studies are warranted to evaluate the capabilities and limitations of DECT in splanchnic flow.
Effect of Pre-sowing Hardening Treatments Using Various Plant Growth Hormones on Two Varieties of Green Gram Germination and Seedling Establishment

Seed germination and seedling establishment of two Green gram varieties ADT 3 and VBN 1 were carried out in the laboratory of Department of Botany, A.V. C.College, Tamil nadu, India. The Green gram seeds were presoaked in various solutions of 5ppm and 10ppm Indole acetic acid (IAA), Gibberellic acid (GA3) and Indole Butyric Acid (IBA), concentrations respectively. The soaked seeds were air dried for 12 hrs and thereafter sown in Petriplates lined with filter paper. The result of the study showed significant difference in percentage germination among the green gram varieties and hormone concentrations. Seeds treated with 5ppm IAA, GA3 and IBA showed significant increases in germination percentage and seedling growth in the two green gram varieties. Germination and seedling growth decreased markedly with increasing hormone concentration. Seeds pre-soaked in distilled water responded poorly. Based on these results, 5ppm concentrations of hormones were found to be the best for enhancing seedling growth in green gram. The result also emphasized that pre-sowing hardening treatment of cowpea seeds in IAA, GA3 and IBA could significantly enhance their germination and seedling growth.
ROLE OF THE HEADS OF THE DEPARTMENTS IN PUBLIC SECTOR UNIVERSITIES IN PROMOTING QUALITY EDUCATION

This study was carried out to investigate the role of the heads of the departments in the light of their competencies in different areas related to the quality assurance practices. The study focused on higher education institutions i.e. universities in Punjab. There were 19 general public sector universities in Punjab. Nine universities were randomly selected as sampled institutions. There were 729 respondents for the study from different departments of the selected universities. These respondents included 81 heads of the departments, 243 university teachers and 504 students of final year master level studies. Three types of research tools were used to collect data. Research tools included questionnaires, competence check list and an interview schedule. Research tools were validated through expert opinion and reliability of the research was established at . 8976 Cronbach Alpha through pilot testing. Data were collected personally by the researcher and at some places with the help of colleagues and friends through mail. Data were analyzed using SPSS software. Descriptive statistics (Mean (X) and Standard Deviation (SD) was used to have the general look of viewpoints of respondents while inferential statistics (t-test) was used to test the hypotheses regarding the difference in the opinion of groups. It was found the most of the heads of the departments/chairpersons motivate the faculty members and initiate changes to improve the performance of students. It was also found that they try to revise the curriculum in the light of national education policy and the directions provided by the higher education commission. It was also seen that they follow the traditional style and don't foster the innovation the departments. Some of the chairpersons and heads of departments provide chances for professional development. All the heads were moderately competent in almost all the competencies. No significant difference was seen in males and females regarding their competencies. In the same way no significant difference was seen regarding competencies in the heads/chairpersons of different subject areas. It was recommended that professional training should be provided to chairpersons to enhance their competencies to improve the quality of education. It was also recommended that the role of QECs in the universities should be made more effective and structured to assess the quality of faculty as well as that of programmes offered in different departments.
Effect of agricultural activities on breeding success of red-wattled lapwing Vanellus indicus.

The study was carried out on a small sample size of 4 km square area in summer season from March to June for two consecutive years 2007-08. Agriculture has been determined as the important factor in survival of ground nesting birds such as Red-wattled Lapwing. Some positive as well as negative effects of the agricultural activities were observed which needs to be further studied on the large scale. Despite high disturbance overall breeding success rate was slightly high in the year 2008 due to various agricultural activities.
Correlation and path coefficient analyses of qualitative and quantitative traits in selected bottle gourd landraces

ABSTRACT Knowledge on associations between yield and related traits is vital to improve selection efficiency in cultivar improvement. This study determined the relationships among qualitative and quantitative traits in bottle gourd landraces using simple correlation and path analyses. Results showed significant and positive correlations between the number of fruits per plant (NFPP) with number of male flowers (NMF), number of female flowers (NFF), plant height (PHT) and number of branches (NB). Number of seeds per fruit (NSPF) positively correlated with PHT, NMF, NFF, NB and fruit weight (FW). Fruit texture, degree of warts (DW), fruit shape (FS), and degree of neck bending, stem-end fruit shape and fruit neck length (FNL) had significant negative correlations with NFPP or NSPF. Path analysis revealed high direct path coefficient value (0.96) between FW and NSPF. Also, positive direct path coefficient value (0.92) was exhibited between NFF and NFPP. Relatively high direct path coefficient value (0.47) was exhibited between DW and NSPF. This study demonstrated that selection for increased FW and NFF may improve genetic gain in seed yield and fruit yield in bottle gourd breeding. Using the above analyses, the following landraces such as BG-06, BG-07, BG-09, BG-11, BG-13, BG-24 and BG-67 were selected for breeding.
Evaluation of a Brief Teacher Coaching Program for Delivering an Early Intervention Program to Preschoolers With Autism Spectrum Disorder

There is a need for research that evaluates the effectiveness of early intervention when delivered in inclusive preschools. In this study, 3 regular preschool teachers were trained to use the Early Start Denver Model with a child with autism spectrum disorder who attended an inclusive preschool. Each teacher worked with 1 child. Teachers received eleven 60-min coaching sessions based on an adapted version of the Early Start Denver Model's parent coaching program. A multiple baseline across participants design was used to evaluate effectiveness in terms of teachers' use of the early intervention techniques and children's levels of participation, imitation, and communication. Data were collected via weekly 10-min video recordings, with 3 follow-up probes conducted 11 weeks following intervention. Teachers improved in their use of early intervention techniques, and children demonstrated improved levels of active participation, but results for child imitation and communication were mixed. Positive results were generally maintained at follow-up. This study provides preliminary support for the effectiveness and feasibility of using a modified coaching program to train preschool teachers to use early intervention techniques from the Early Start Denver Model.
THE EFFECT OF EXOGENOUS TESTOSTERONE ON GROWTH AND SECONDARY SEXUAL CHARACTER DEVELOPMENT IN JUVENILES OF SCELOPORUS VIRGATUS

Closely related species often vary considerably in the degree of sexual size dimor- phism and in the expression of secondary sexual characters. Relatively little is known about the proximate mechanisms underlying among-species variation in sexually dimorphic traits. I examined the influence of exogenously administered testosterone on body growth and on the expression of two possible secondary sexual characters (blue ventral coloration and femoral pore secretion) in the striped plateau lizard, Sceloporus virgatus. Male and female hatchlings were given testosterone- filled or empty (control) implants at approximately 40 days of age. Testosterone-treated females experienced a significant reduction in the rate of growth of body mass and body length over the six-month period following implantation. A similar but non-significant trend for reduced rate of body growth was detected in testosterone-implanted males. Testosterone had no effect on the final size or intensity of the blue throat patch, but the testosterone-implanted males increased in patch size more slowly than control males. Both males and females greatly increased their femoral pore secretions in apparent response to the dose of testosterone. Testosterone-implanted males had great- ly enlarged tail bases relative to those of control males. In this species, then, the lack of extensive blue ventral coloration is apparently not due to a corresponding reduction of testosterone secretion in early life.
Physicochemical, Microbiological and Oxidative Changes During Refrigerated Storage of n‐3 PUFA Enriched Cooked Meat Sausages with Partial NaCl Substitution

Fil: Marchetti, Lucas. Provincia de Buenos Aires. Gobernacion. Comision de Investigaciones Cientificas. Centro de Investigacion y Desarrollo en Criotecnologia de Alimentos. Consejo Nacional de Investigaciones Cientificas y Tecnicas. Centro Cientifico Tecnologico Conicet - La Plata. Centro de Investigacion y Desarrollo en Criotecnologia de Alimentos. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Centro de Investigacion y Desarrollo en Criotecnologia de Alimentos; Argentina
The Root Nodule Symbiosis between Rhizobium 'hedysari' and its drought-tolerant host Hedysarum coronarium.

The symbiotic interaction occurring between the legume Hedysarum coronar­ ium, a drought-tolerant forage crop relevant for the Mediterranean basin, and its natural host-specific, nitrogen-fixing bacterial symbiont, Rhizobium 'hedysari ', was studied by combined light and transmission electron microscopy. Several unusual morphological features of this root nodule symbiosis were found: in nature the plant is able to form modified pseudo-roots called 'shovels'; we observed that these structures can form independently from the presence of bacteria. Computer-assisted image analyses suggested three size classes of root hair lengths, one of which was longer than 600 J-lm. The primary infection route is through infection threads in deformed root hairs. Transmission electron micxoscopy of infection threads within the nodule revealed an atypical double layered wall. Nodules were indeterminant with an apical meristem, infection zone, and central bacteroid tissue. The predominant shape of differentiated R. 'hedysari' bacteroids is cruciform.
Data Mining Technique Applied To DNA Sequencing

CpG islands (CGIs) play a vital role in genome analysis as genomic markers. Identification of the CpG pair has contributed not only to the prediction of promoters but also to the understanding of the epigenetic causes of cancer. In the human genome [1] wherever the dinucleotides CG occurs the C nucleotide (cytosine) undergoes chemical modifications. There is a relatively high probability of this modification that mutates C into a T. For biologically important reasons the mutation modification process is suppressed in short stretches of the genome, such as ‘start’ regions. In these regions [2] predominant CpG dinucleotides are found than elsewhere. Such regions are called CpG islands. DNA methylation is an effective means by which gene expression is silenced. In normal cells, DNA methylation functions to prevent the expression of imprinted and inactive X chromosome genes. In cancerous cells, DNA methylation inactivates tumor-suppressor genes, as well as DNA repair genes, can disrupt cell-cycle regulation. The most current methods for identifying CGIs suffered from various limitations and involved a lot of human interventions. This paper gives an easy searching technique with data mining of Markov Chain in genes. Markov chain model has been applied to study the probability of occurrence of C-G pair in the given gene sequence. Maximum Likelihood estimators for the transition probabilities for each model and analgously for the model has been developed and log odds ratio that is calculated estimates the presence or absence of CpG is lands in the given gene which brings in many facts for the cancer detection in human genome.