Miracle-dz/UniFAR-FTUs huggingface dataset:
The protective effect of topical fluoride treatments in dentine lesions

Non restorative cavity control (NRCC) is a non to minimally invasive dental approach in dentine caries management which can be applied to cavitated dentine lesions in the primary and permanent dentition. This approach could be supported by topical fluoride applications to enhance caries arrestment. Caries arrestment is a clinical sign of the success of the NRCC approach. The overall aim of this thesis was to understand more closely the chemical and histological (microradiographic) aspects of this fluoride induced arrestment. Therefore, this thesis has investigated these aspects in dentine lesions after treatment with various topically applied fluoride products (SDF, NaF, TiF4 and SnF2), and to examine which product performs best in dentine caries arrestment in an in vitro de- and remineralization model. The current finding showed that all fluoride products used in the current thesis were effective in inhibiting demineralization or enhancing remineralization, depending on the formulas and concentration of the product. SDF, however, was the most effective product in dentine caries management. Therefore, it was of interest to compare the effect of equal fluoride concentrations as either SDF or KF on dentine lesions to examine whether the superior effect of the SDF is due to both the fluoride and silver components, or only to the high fluoride concentration. The results suggest that the effect depended on the high fluoride concentration. In conclusion, the chemical and histological results of these products confirmed the superiority of the SDF treatment in inhibiting dentine demineralization and enhancing dentine remineralization during the pH-cycling.
Role of N-terminal pro b-type natriuretic peptide (NT-pro-BNP) in compensated chronic kidney disease

Aim: To evaluate the role of N-terminal pro b-type natriuretic peptide (NT-pro-BNP) in the evaluation of hypervolemia in chronic kidney disease (CKD) and its relationship with CKD. Methods: Sixty compensated chronic kidney disease patients enrolled in this study. NT-pro BNP levels and other routine biochemical laboratory parameters are studied. The associations between results were analyzed. Results: NT-pro BNP levels were correlated with urea (r = 0.66, p <0.01), creatinine (r = 0.69, p <0.01) and phosphorus (r = 0.36, p <0.01) values and were negative correlated with hemoglobin (r = -0.32, p = 0.01), hematocrit (r = -0.36, p <0.01), albumin (r = -0.29, p = 0.02) and glomerular filtration rate (GFR) values (r = -0.35, p <0.01). Conclusion: The positive correlation between NT-pro BNP levels and urea and creatinine values in our study and the negative correlation with GFR support that the severity of hypervolemia increases as the CKD stage progresses. BNP and NT-pro BNP are strong predictors of all-cause cardiovascular mortality in asymptomatic CKD patients. In the light of all these data, it is possible to suggest that NT-pro BNP is associated with hypervolemia and therefore increased cardiovascular mortality in subjects with CKD.
A Study on Kazakh Academicians’ Information Technology Acceptance

Information technologies (ITs), which have become one of the key enablers of success in educational competitiveness, have made the understanding of user technology acceptance crucial. The failures of IT investment and implementation lead to unwanted organizational outputs. A better understanding of the contributions of the factors determining the individual’s intention to use (IU) IT during the acceptance process will help to prevent probable visible and invisible losses. This research attempts to validate a new technology acceptance model (TAM) version extended with the constructs of Subjective Norm (SN) and Facilitating Conditions (FC) in the context of Kazakh Academicians. The results indicate that this variant of extended TAM will be able to facilitate managers to appropriately employ their strategic decisions on the investments and implementations of IT in educational settings while contributing to the technology acceptance research field. On the other hand, the model is open to development for a higher predictive value.
3D Simulation Model of Tidal, Internal Mixing and Turbulent Kinetic Energy of Palu Bay

Sabhan*†, Alan Frendy Koropitan**, Mulia Purba*** and Widodo Setiyo Pranowo**** *Marine Science, Postgraduate Study Program, IPB University/Department of Physics, Faculty of Mathematical and Natural Sciences, Tadulako University, Indonesia, Perumahan Bumi Mallantan Rezkita Blok C2/1, Jl Roviega, Tondo, Palu City, Central Sulawesi, Indonesia **Department of Marine Science and Technology, Faculty of Fisheries and Marine Science, IPB University, Jl.Raya Dramaga, Bogor 16680, West Java, Indonesia ***Department of Marine Science and Technology, Faculty of Fisheries and Marine Science, IPB University, Jl.Raya Dramaga, Bogor 16680, West Java, Indonesia ****Department of Hydrography, Indonesian Naval Postgraduate School (STTAL)/Researcher at Marine Research Center, Indonesian Ministry of Marine Affairs & Fisheries, Indonesia † Corresponding author: Sabhan
Recreation, relaxation or something else? Exploring the motives for visiting the wellness hotels in Serbia

Nowadays, the various forms of health tourism are gaining popularity in the world tourism. In the last decade, health tourism is featuring a growing development primarily in the area of wellness tourism. Wellness services are today a very important criterion for guests when deciding which hotel to choose. For this reason it is necessary to pay great attention to planning and design of this part of the hotel product but also to explore the motives for visiting wellness hotels in order to adjust the hotel offer to the most dominant consumers. In order to follow the trends, wellness hotels should specialize in providing health information and a wide range of recreation and relaxation programs. Therefore, in order to keep up with good quality, hotel managers should examine the expectations, motives of the visit and the needs of their customers. Based on this, the main objectives of this research are to examine the characteristics of the motivational behavior of the tourists visiting the wellness hotels, explore the role of need for recreation in visiting wellness hotels. In addition, the study explores the relationship between the socio-demographic characteristics of respondents and their motivational behavior in relation to the wellness facilities in Serbian hotels. Keywords— motivation factors, wellness hotels, Serbia
Optimal triggering of jet bifurcation: an example of optimal forcing applied to a time-periodic base flow

The present article aims at optimising the spread of a bifurcating jet: a jet that combines axisymmetric and helical forcing to achieve increased mixing in a preferential plane. Parekh et al. (Tech. Rep. TF-35, Stanford University, 1988) explained such a bifurcation as the result of nonlinear interaction between ring vortices (triggered by $m=0$ axisymmetric forcing), shifted off-axis in alternate directions (owing to $m=1$ helical forcing). Following this idea, we linearly optimise the periodic helical forcing to be applied at the inlet, in order to maximally displace the ring vortices of an axisymmetrically forced jet. Two norms are introduced for evaluating the effect of helical forcing onto the helical response: the standard ${\mathcal{L}}_{2}$-norm and a semi-norm reflecting the off-axis vortex displacement. The linear results show one dominant forcing mode over the entire Strouhal band studied ($0.35\leqslant St\leqslant 0.8$), with a large gain separation from suboptimals. The dominant forcing is mainly radial, independent of the chosen response norm, and provides a gain at least five times larger than what was achieved by previous ad hoc forcing strategies. Superposition of base flow and linear results show the alternate shifting and twisting provoked by the the small-amplitude helical forcing, which is an essential ingredient for triggering jet bifurcation. When tested in three-dimensional direct numerical simulations, low-amplitude helical forcing achieves efficient bifurcation at all Strouhal values studied. At high Strouhal numbers, an additional central branch emerges in the mean flow, leading to trifurcation. Across all frequencies, compared with ad hoc forcing strategies, the optimal forcing triggers a much stronger and robust spreading, by moving the bifurcation point upstream. As a result, bifurcating jets are observed over a much larger Strouhal band ($0.35\leqslant St\leqslant 0.8$) compared with the band where ad hoc forcing achieves bifurcation in our setting ($0.4\leqslant St\leqslant 0.5$).
Fostering Resident Pro-Environmental Behavior: The Roles of Destination Image and Confucian Culture

Residents are important participants and stakeholders in destination development. Identifying factors that assist in predicting resident pro-environmental behavior (PEB) may contribute to enhanced sustainability. Based on a traditional Chinese culture, this research constructed a model of resident PEB by introducing pro-environmental destination image (PEDI) and Confucianism as the independent and moderating variables, respectively. The structural equation modeling for 402 residents indicated the model had a satisfactory level of predictive power for PEB. The results showed that: (1) PEDI positively affected residents’ environmental identity, pro-environmental attitudes, and PEB; (2) environmental identity and pro-environmental attitudes completely mediated the impact of PEDI on residents’ PEB; and (3) Confucian culture had a positive U-shaped moderating effect in the relationships among these four variables. Overall, these findings advance the understanding of the formation of PEB in Confucian culture and provide theoretical and practical implications for fostering residents’ PEB.
Web-Based Graphic Representation of the Life Course of Mental Health: Cross-Sectional Study Across the Spectrum of Mood, Anxiety, Eating, and Substance Use Disorders

Background Although patient history is essential for informing mental health assessment, diagnosis, and prognosis, there is a dearth of standardized instruments measuring time-dependent factors relevant to psychiatric disorders. Previous research has demonstrated the potential utility of graphical representations, termed life charts, for depicting the complexity of the course of mental illness. However, the implementation of these assessments is limited by the exclusive focus on specific mental illnesses (ie, bipolar disorder) and the lack of intuitive graphical interfaces for data collection and visualization. Objective This study aimed to develop and test the utility of the Tulsa Life Chart (TLC) as a Web-based, structured approach for obtaining and graphically representing historical information on psychosocial and mental health events relevant across a spectrum of psychiatric disorders. Methods The TLC interview was completed at baseline by 499 participants of the Tulsa 1000, a longitudinal study of individuals with depressive, anxiety, substance use, or eating disorders and healthy comparisons (HCs). All data were entered electronically, and a 1-page electronic and interactive graphical representation was developed using the Google Visualization Application Programming Interface. For 8 distinct life epochs (periods of approximately 5-10 years), the TLC assessed the following factors: school attendance, hobbies, jobs, social support, substance use, mental health treatment, family structure changes, negative and positive events, and epoch and event-related mood ratings. We used generalized linear mixed models (GLMMs) to evaluate trajectories of each domain over time and by sex, age, and diagnosis, using case examples and Web-based interactive graphs to visualize data. Results GLMM analyses revealed main or interaction effects of epoch and diagnosis for all domains. Epoch by diagnosis interactions were identified for mood ratings and the number of negative-versus-positive events (all P values <.001), with all psychiatric groups reporting worse mood and greater negative-versus-positive events than HCs. These differences were most robust at different epochs, depending on diagnosis. There were also diagnosis and epoch main effects for substance use, mental health treatment received, social support, and hobbies (P<.001). User experience ratings (each on a 1-5 scale) revealed that participants found the TLC pleasant to complete (mean 3.07, SD 1.26) and useful for understanding their mental health (mean 3.07, SD 1.26), and that they were likely to recommend it to others (mean 3.42, SD 0.85). Conclusions The TLC provides a structured, Web-based transdiagnostic assessment of psychosocial history relevant for the diagnosis and treatment of psychiatric disorders. Interactive, 1-page graphical representations of the TLC allow for the efficient communication of historical life information that would be useful for clinicians, patients, and family members.
The Ostrich Should be the National bird of India

Abstract should be structured for Original Article and unstructured for others. It should not exceed 250 words. Structured abstract should follow the sections: Purpose, Methods, Result and Conclusion. Tables and figures: Each table and figure should be on a separate page and numbered consecutively. Tables should be sent in a separate text file and the images as a jpeg file. References Should be numbered in the order of appearance in the text and should be presented in square brackets, not as superscript or subscript. End note/Footnote tools should not be used for referencing. References should be mentioned in the standard style of Index medicus (Vancouver style)Author 1, Author 2. Title of the article. Name of Journal Year; Volume: Page numbers. (For Journal article) Author 1, Author 2. Title of chapter. In: Names of Editors. Title of book. Publisher name and place, year and edition number; page numbers. (For a book article) Author/s. Title of the article. Address of the website, date last updated, date accessed. (For articles accessed from the worldwide web) Where the authors are more than six, mention the initial six authors followed by et al. Unpublished articles should not be listed as references and should be highlighted in the body of the article as personal communication in parentheses. As far as possible, reference to abstracts should be avoided, but whenever necessary, they should be mentioned in the references as (abs.). Key points 3-5 key points should be provided at the end of the text which highlight the salient features. Disclosure and copyright transfer All manuscripts should be accompanied by the cover letter carrying the disclosure and copyright transfer statement which must be signed and dated by all the authors without which the manuscript will not be accepted for review and possible publication. If the data in the manuscript were presented at a scientific meeting, the place of data of presentation, and name of the meeting should be stated on the title page. Any proprietary or financial interest in any product mentioned in the manuscript should be stated on the title page. Checklist for attachments to the e-mail1. Covering letter duly signed by all authors (scanned document to be attached) The following lines should be a part of the covering letter “The authors are ready to assign the copyright ownership of this manuscript to the “Delhi Journal of Ophthalmology” once the article is accepted for publication in the journal.
Causative factors for time delays in patients with acute st-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention

Background/Aims: The time delay for a patient from the onset of disease symptoms until the reperfusion therapy is one of the biggest interruptions in early reperfusion therapy in patients with acute ST-segment elevation myocardial infarction (STEMI). Here, we evaluated both the duration and nature of these time delays to facilitate early patient reperfusion therapy. Methods: Patients with acute STEMI who were undergoing primary percutaneous coronary intervention (PCI) were prospectively enrolled in the Chungnam National University Hospital from January 2005 to December 2007. Results: From a total 364 patients (mean age: 64±12 years) the mean time interval from the onset of symptoms to the decision to visit a hospital was 101.4±10.6 (median: 50.0) minutes. The mean time interval for the onset of disease symptoms to the patient arrival at the emergency room (ER) (pre-hospital delay) was 222.1±12.4 (median: 171.5) minutes. The mean time interval from the ER to reperfusion (door to balloon time) was 89.0±6.0 (median 65.0) minutes. The mean time interval from the onset of symptoms to successful reperfusion therapy (pain to balloon time) was 311±13.6 (median: 250) minutes. The factors associated with these significant time delays were mainly: residency in rural areas, the use of private transport in preference to an ambulance and finally the transferal of patients from other hospitals. As a result of multivariate analysis the latter was found to be the most significant causative factor. Conclusions: This study demonstrates that there is a significant pre-hospital time delay in patients with STEMI. Thus, a media campaign explaining STEMI symptoms, the importance of early visits to the emergency department, the use of an ambulance, and the activation of the base hospital for efficient patient transfer (particularly in rural areas) may reduce this time delay in patients with STEMI and avoid interruptions to otherwise efficient reperfusion therapies. (Korean J Med 78:586-594, 2010)
Single-cell analysis for drug development using convex lens-induced confinement (CLiC) imaging

www.BioTechniques. com 210 No. 5 | Vol. 67 | © 2019 Corey Nislow ABSTRACT New technologies have powered rapid advances in cellular imaging, genomics and phenotypic analysis in life sciences. However, most of these methods operate at sample population levels and provide statistical averages of aggregated data that fail to capture single-cell heterogeneity, complicating drug discovery and development. Here we demonstrate a new single-cell approach based on convex lens-induced confinement (CLiC) microscopy. We validated CLiC on yeast cells, demonstrating subcellular localization with an enhanced signal-to-noise and fluorescent signal detection sensitivity compared with traditional imaging. In the live-cell CLiC assay, cellular proliferation times were consistent with flask culture. Using methotrexate, we provide drug response data showing a fivefold cell size increase following drug exposure. Taken together, CLiC enables highquality imaging of single-cell drug response and proliferation for extended observation periods. One of the driving forces in systems biology research is the emergence and development of new data-acquisition tools and technologies to better understand b io log ica l and biochemical mechanisms at the single-cell level. At present, most practical molecular and cell biology methods capture the average response of a cell sample population. However, results from these approaches can be misleading due to cellular heterogeneity. Such variation may arise from diverse genetic and nongenetic factors, including noise in gene expression. Factors that substantially define the amplitude of such noise include regulatory dynamics, transcription rates, genetic factors and intracellular copy numbers of molecules involved in the genetic network [1]. Single-cell heterogeneity is indeed a well-known phenomenon in microbial resistance and evolution studies, as well as in cancer research. For instance, most cancer cell lines display genomic alterations, as well as other forms of heterogeneity such as chromosomal instability [1,2]. Stochastic cellular process fluctuations, including the state, location, activity and concentration of polymerases, transcription factors and gene expression regulators, may also lead to diversification in an initially uniform cell population [3]. These variations can have a significant impact on the growth and environmental stress response of cells and cannot be captured using conventional cell biology methods. For instance, conducting a drug response analysis in yeast often requires recording its Single-cell analysis for drug development using convex lens-induced confinement imaging
EVALUATION OF SOME NEW CHEMISTRY INSECTICIDES AGAINST COTTON WHITEFLY (BEMISIA TABACI GENN.) (HEMIPTERA: ALEYRODIDAE)

Cotton Gossypium hirsutum (L.) is the most rather valued golden cash crop of the country, which has a first-rate contribution for food, agriculture and textile industries products. All plant components of the cotton are very useful in our daily life. The most important parts of the cotton are the cotton seed and fiber or lint (Sarwar et al., 2013 a). However, in terms of yield, cotton contributed 14.5 percent of GDP (PES, 2014-15). Cotton production stood at 13,983 thousand bales of cotton (PES, 2014-15). It also contributes 69.5% share in country wide oil production (Awan, 1994). There are a number of reasons for low cotton yield in Pakistan that includes lack of knowledge to farmers, deficiency of progressive technologies, higher incidence of insect and pest assault, high price of pesticides and contamination in pesticides (Ahmad and Sarwar, 2013). Cotton is a very delicate crop in terms of pest complex being attacked by different insect pests from germination to harvesting (Sarwar, 2013 a). More than 1326 species of insects have been found to attack on cotton in the world (Atwal, 2002). Cotton is attacked by both sucking pests and bollworms. Among sucking pests whitefly, Bemisia tabaci Genn. is the most detrimental sucking pest (Amin et al., 2008). It sucks the cell sap e from the underside of leaves and deposits the droplets of honeydew on the leaves, that results in sooty mold development. It also hinders the foliar photosynthesis and reduces yield and quality (Bi et al., 2001). Whitefly is also liable for spreading cotton leaf curl virus (CLCV) ailment. Plant protection plays crucial role in the successful production of cotton crop and saves it from the pest attack. In Pakistan, major emphasis is on the use of chemical insecticides and their use is increasing every year. Pesticides cost more than 10 billion rupees are imported, out of which about 70-80% are used against cotton pests (Anonymous, 2008). It is the dire need to use the new-chemistry insecticides which are not only specific to the targeted pest but also safer ABSTRACT ARTICLE INFORMATION
Olowe and Balogun -Social capital and well-being of rural households in Southwest Nigeria- a capability approach

Majority of rural households in Nigeria are engaged in farming with small holdings and continue to experience low well-being in spite of several rural and agricultural development programs embarked upon by successive governments. Social capital has been identified as a potential instrument for improving well-being. This study examined the social capital and well-being of rural households in Southwest Nigeria using the capability approach. The primary data employed in the study were obtained with the aid of a semi-structured questionnaire from 439 households using a four-stage sampling technique. A wide range of indicators in nine dimensions of life of the households were used to generate a well-being index. Social capital variables used in the study were based on network participation, collective action and trust. Data were analyzed using descriptive statistics, fuzzy set and the ordered Probit model. Average meeting attendance was four out of five association meetings while well-being index in the study area is 0.5849. The result of the ordered Probit regression revealed that meeting attendance and trust improved well-being. The study recommends that rural households should be encouraged to increase their activities in social network to improve their well-being.