Miracle-dz/UniFAR-FTUs huggingface dataset:
The Effect of Milling on the Ethanolic Extract Composition of Dried Walnut (Juglans regia L.) Shells

This study investigates the ethanolic extract of dried walnut (Juglans regia L.) shells upon hammer milling (HM) and ball milling (BM) grinding processes. Marked differences were observed in the attenuated total reflection Fourier-transform infrared (ATR-FTIR) spectra. The two extracts were investigated by reversed-phase liquid chromatography coupled with electrospray ionization and high-resolution mass spectrometry (RPLC-ESI-HRMS). Following enzymatic digestion, the fatty acids (FAs) were examined, and tandem MS of epoxidized species was applied to establish the C-C double bond position; the most abundant species were FA 18:2 Δ9,12, FA 18:1 Δ9, and FA 18:3 Δ9,12,15. However, no significant qualitative differences were observed between FAs in the two samples. Thus, the presence of potential active secondary metabolites was explored, and more than 30 phenolic compounds, including phenols, ellagic acid derivatives, and flavonoids, were found. Interestingly, the HM samples showed a high concentration of ellagitannins and hydrolyzable tannins, which were absent in the BM sample. These findings corroborate the greater phenolic content in the HM sample, as evaluated by the Folin–Ciocalteu test. Among the others, the occurrence of lanceoloside A at m/z 391.1037 [C19H20O9-H]−, and a closely related benzoyl derivate at m/z 405.1190 (C20H22O9-H]−), was ascertained. The study provides valuable information that highlights the significance of physical pre-treatments, such as mill grinding, in shaping the composition of extracts, with potential applications in the biorefinery or pharmaceutical industries.
A New Lysosome-Targeted NIR Fluorescent Probe for Specific Detection of Cysteine over Homocysteine and Glutathione

In this paper, by modifying the thioxanthene-benzothiozolium fluorophore, BCy-Cys, a lysosome-targeted near-infrared (NIR) fluorescent probe was synthesized for the detection of cysteine (Cys) from homocysteine (Hcy)/glutathione (GSH). As expected, BCy-Cys exhibited high selectivity and high sensitivity for detection of Cys over Hcy/GSH, with an extremely low limit of detection at 0.31 μM, marked by obvious color changes. HRMS was conducted to confirm that the fluorescence intensity at 795 nm was significantly enhanced by the enhancement of intramolecular charge transfer (ICT). Importantly, BCy-Cys could be used to visualize both exogenous and endogenous lysosomal Cys, signifying its potential application in complex organismal systems.
Promoting Health Students’ Well-Being: The Study Protocol of a Quasi-Experimental Intervention Study

Introduction: Several studies identified high prevalence of anxiety, stress, and depression for health students, including paramedic students. For this reason, the health students’ well-being represents a public health issue. To improve this situation, we need to develop interventions at the beginning of health studies. The implementation of occasional and/or regular well-being promotion interventions meets a real need for many of health students. Objectives of this study: We aim to assess a well-being promotion intervention among paramedic students in Le Havre (France). Methods and analysis: This is a protocol of monocentric quasi-experimental study designed to assess the impact of the intervention on well-being, resilience, self-esteem, and stress among paramedic students throw validated scales distributed before the intervention and 8 months after. Students’ satisfaction will be assessed through a questionnaire. A first analysis will describe the study population. The comparison of average scores will be performed. The results of satisfaction questionnaire will allow evolving the intervention to best meet the needs of students next year. Discussion: The scientific publications on this theme will enrich the literature and contribute to the integration of this approach of well-being promotion nationally and internationally. The expected benefits from this study are the adoption of a healthy lifestyle, the improvement of students’ well-being and their awareness of the importance of health promotion in patients’ care. Ethics and dissemination: The project received ethical approval from the Research Ethics Board of Le Havre Hospital. The results will be disseminated via scientific publications and conference presentations.
Analysis of Nutritional Characteristics and Willingness to Pay of Consumers for Dry-Cured Sausages (Salchichón) Made with Textured Seed Oils

The consumption of processed meat products beyond recommended limits has been associated with serious health conditions, including heart disease, diabetes, and cancer. In an effort to create healthier options, the meat industry is exploring alternatives to animal fat in processed meats. This study focuses on replacing animal fat in dry-cured sausages (Salchichón) with textured chia, poppy, melon, and pumpkin oils. The research aims to evaluate the physical and nutritional changes resulting from this substitution and assess consumer acceptance through sensory analysis. The use of seed oils led to slight color changes and comparable texture, except for cohesiveness. The incorporation of textured seed oils resulted in reduced fat content, increased proportions of ashes and protein, and decreased energy value. The fatty acid composition showed lower proportions of saturated fatty acids and increased polyunsaturated fatty acids. Sensory analysis revealed that the control sample with pork fat received the highest ratings for appearance, texture, and taste, while samples with higher seed oil percentages scored lower due to color, cohesiveness, and specific flavors from the seed oils. Despite these variations, consumers demonstrated a high level of acceptability for all samples. Choice analysis results indicated that higher prices had a negative impact on consumer willingness to purchase, while the use of the 100% Iberian pig breed and animal welfare labels positively influenced purchasing attitudes. Regarding the presence of a pumpkin seed oil label in the product, a negative willingness to pay was reported. However, significant individual variation was reported for this attribute, indicating the existence of consumer segments with more positive attitudes toward these innovative dry-cured sausages.
PENGARUH KECERDASAN EMOSIONAL DAN MOTIVASI BELAJAR TERHADAP HASIL BELAJAR BAHASA INGGRIS

ABSTRAK Tujuan Penelitian adalah untuk mengetahui pengaruh Kecerdasan Emosional dan Motivasi Belajar terhadap hasil belajar bahasa Inggris. Metode yang digunakan dalam penelitian ini adalah metode survey dengan teknik random sampling yang diambil dari 2 Madrasah Aliyah swasta di Kecamatan Kebon Jeruk. Pengumpulan data dilakukan dengan kuisioner dan hasil penilaian akhir semester (PAS) dengan analisis data menggunakan analisis jalur. Hasil pengujian hipotesis menunjukkan bahwa: 1) Terdapat pengaruh langsung Kecerdasan Emosional terhadap hasil belajar bahasa Inggris. 2) Terdapat pengaruh langsung Motivasi Belajar terhadap hasil belajar bahasa Inggris 3) Terdapat pengaruh langsung Kecerdasan Emosional terhadap Motivasi Belajar. 4) Tidak terdapat pengaruh tidak langsung Kecerdasan Emosional terhadap hasil belajar bahasa Inggris melalui Motivasi Belajar. Kata Kunci : Kecerdasan Emosional, Motivasi Belajar , Hasil Belajar Bahasa Inggris
Nutritional Assessment of Plant-Based Meat Products Available on Hong Kong Market: A Cross-Sectional Survey

Background: Plant-based meat (PBM) takes up ever-increasing market shares and draws great attention from both customers and retailers these days. However, little is known about the nutritional quality of PBM products. Objective: This study intended to profile and evaluate the overview nutrition of PBM with equivalent meat products on the Hong Kong market. Methods: We conducted a cross-sectional survey of 274 PBM and 151 meat products from 27 different brands on the Hong Kong market in October 2022. The nutritional differences between PBM and meat products were assessed using analysis of covariance (ANCOVA) and two independent sample t-test. The nutritional quality of PBMs was evaluated according to nutrient reference value, front-of-package (FoP) criteria and nutritional score. Results: PBM had relatively lower energy density, total fat, saturated fat, protein, and salt compared to meat. According to the FoP criteria, 91.36%, 17.88%, and 99.34% of PBMs were labeled as medium to high in fat, salt, and sugar, respectively. Through ingredient analysis of 81 PBM products, soy and canola were the main source of protein and fat. Conclusions: PBM products have a roughly better nutrient quality compared to muscle-based meat, though there is still potential for further refinement in terms of production, consumption, and regulation.
The religiosity of the secular: the case of self-help

ABSTRACT Religious decline is an oft-repeated fact proposed by secularization-based studies. It stems from the preconceived notion that religion and the secular are against each other. A major problem with this binary is that the secular is considered to be devoid of any religiosity. This paper highlights the opposite avenue of research trodden by a few scholars who have disregarded the said binary and navigated the religiosity of the secular to which far too little attention has been paid. Particularly, this article focuses on the religiosity of self-help which is mostly considered as a secular movement. To the best of the author’s knowledge, there is only one study which has empirically examined this topic while it occupies a special place in our understanding of religion. The space in this paper does not allow for a full discussion of the issue. Therefore, it generally highlights the new path to understanding religion and potential points of departure for exploring self-help’s religiosity. Finally, the paper briefly discuses why this topic deserves serious attention.
Therapeutic Potential of Minor Cannabinoids in Dermatological Diseases—A Synthetic Review

Dermatological diseases pose a significant burden on the quality of life of individuals and can be challenging to treat effectively. In this aspect, cannabinoids are gaining increasing importance due to their therapeutic potential in various disease entities including skin diseases. In this synthetic review, we comprehensively analyzed the existing literature in the field of potential dermatological applications of a lesser-known subgroup of cannabinoids, the so-called minor cannabinoids, such as cannabidivarin (CBDV), cannabidiforol (CBDP), cannabichromene (CBC), tetrahydrocannabivarin (THCV), cannabigerolic acid (CBGA), cannabigerol (CBG), cannabielsoin (CBE), cannabimovone (CBM) or cannabinol (CBN), while drawing attention to their unique pharmacological properties. We systematically searched the available databases for relevant studies and analyzed the data to provide an overview of current thematic knowledge. We looked through the full-text, bibliographic and factographic databases, especially Scopus, Web of Science, PubMed, Polish Scientific Journals Database, and selected the most relevant papers. Our review highlights that minor cannabinoids exhibit diverse pharmacological activities, including anti-inflammatory, analgesic, antimicrobial, and anti-itch properties. Several studies have reported their efficacy in mitigating symptoms associated with dermatological diseases such as psoriasis, eczema, acne, and pruritus. Furthermore, minor cannabinoids have shown potential in regulating sebum production, a crucial factor in acne pathogenesis. The findings of this review suggest that minor cannabinoids hold therapeutic promise in the management of dermatological diseases. Further preclinical and clinical investigations are warranted to elucidate their mechanisms of action, determine optimal dosage regimens, and assess long-term safety profiles. Incorporating minor cannabinoids into dermatological therapies could potentially offer novel treatment options of patients and improve their overall well-being.
Using the P-O Fit Theory to Examine Work Attitudes of Employees in Shanghai, China

This study investigates factors which transform work attitudes among Chinese employees. Using purposive sampling, a survey questionnaire was distributed to employees in Shanghai, where 479 were usable. Firstly, the study examines the relationship between demographic factors and employees' work attitudes. Secondly, the Person-Organisation Fit theory is used to examine the relationship between generational differences, personality traits, organisational culture and work attitudes. PLS-SEM results show that all three factors are positively related to work attitudes. This study is unique as it uses the P-O fit theory to understand work attitudes, which is essential for employees' well-being and quality of life.
Interannual variability in Indian Ocean surface waters and tuna-environment relationships : filling the gaps with a coupled bio-physical ocean model

Indian Ocean effects of ENSO and the Indian Ocean Dipole or Zonal Mode (IOZM) were investigated in 1961-2001 hindcasts from a coupled bio-physical ocean model, NEMO-PISCES. The basin-wide patterns were investigated for gridded fields of sea surface temperature (SST), depth of the 20°C isotherm (Z20; as a proxy of thermocline depth) and integrated chlorophyll (CHL). Empirical orthogonal functions analyses (EOFs) confirmed that the dominant interannual mode of variability in surface temperature is an ENSO-related basin-scale warming signal, while those in Z20 and CHL are a dipolar zonal pattern across equatorial regions. The thermocline depth (as estimated by Z20) is inversely related to chlorophyll productivity across most of the Indian Ocean, due to its important role in controlling the amount of nutrients reaching sun-bathed surface waters. As a result, the strong IOZM effects on thermocline depths via Rossby Waves, Kelvin Waves and changes in Wyrtki Jet flow, translate to mirror-image patterns in chlorophyll anomalies across much of the basin. Composite averages were used to describe these patterns, differentiating among distinct combinations of positive and negative ENSO and IOZM events, as well as those that occur on their own ('pure' ENSO and IOZM events). ENSO and IOZM do have distinct anomaly expressions in the Indian Ocean, with SST being under predominantly ENSO control, but Z20 and CHL anomalies being affected mainly by IOZM dynamics when the two climate modes co-occur, as in 1997. Results presented here compare well to previous studies based on a range of data sources, and are perhaps most valuable and novel in their description of large-scale phytoplankton responses to interannual climatic extremes. In addition, the integrated chlorophyll fields reveal Rossby Wave-induced interannual anomalies in the southern tropical Indian Ocean, that are not well detected by SeaWiFS sensors. Such diagnostic anomalies have important implications for predicting physical or ecosystem responses
High Transcriptional Activity and Clinical Correlations in Eosinophils of Patients with Late-Onset Asthma

Background The immunological features of eosinophils in early-onset asthma (EOA) differ from those in late-onset asthma (LOA). Clinical trials of anti-interleukin-5 (IL-5) treatment for severe eosinophilic asthma showed a better response for LOA patients than EOA patients. We wonder if the transcriptional activity of activated eosinophils was different in EOA and LOA. Methods Eosinophils obtained from well-controlled EOA and LOA patients and normal subjects were compared in terms of the mRNA expression of activation-related genes and specific markers related to cell functions in eosinophils activated by IL-5 or IL-17. The correlation between mRNA expression and clinical features and lung function was further analyzed. Results The transcriptional expression of most genes was higher in activated eosinophils from LOA patients than in those from EOA patients and normal subjects. After IL-17 stimulation, the expression of certain genes was higher in atopic EOA patients than in non-atopic EOA patients. Similar observation was noted in obese EOA patients. After IL-5 stimulation, the transcriptional expression of most genes in eosinophils from LOA patients was negatively correlated with indicators of lung function. These correlations were less pronounced in EOA patients: After IL-17 stimulation, some genes in EOA patients were negatively correlated with post-bronchodilator changes in lung function. Conclusion This study describes differences in the transcriptional active patterns of eosinophils and their correlation to atopy and obesity by age of onset. High transcriptional activity in activated eosinophils and a negative correlation to lung function indicate the importance of eosinophils in the pathogenesis of LOA.
Measuring Financial Inclusion in Southeast European Countries Using Multidimensional Index of Financial Inclusion

This paper provides an insight into measuring financial inclusion through a multidimensional index of financial inclusion in Southeast European countries (SEE). We used a two-stage principal component analysis to extract dimensions of financial inclusion. Data were obtained from two sources, the World Bank Global Findex Survey (WB-GFS) data base and the International Monetary Fund Financial Access Survey data (IMF-FAS), for twelve SEE countries for the years 2011, 2014, 2017, and 2021. The research confirms that financial inclusion can be measured using two dimensions in terms of access as one factor and usage and availability as the second factor. Practical implications of this research are in ensuring an adequate measure of the level of financial inclusion for SEE countries that can be used for further research related to understanding the underlying factors contributing to financial inclusion, barriers to financial inclusion as well as the impact of financial inclusion on economic growth and poverty alleviation.
Analysis of determining optimal portfolio in BPKH’s portfolios using Tangency Portfolio model

Purpose – This study aims to analyze the actual portfolio of BPKH from the hajj fund investment and examine the optimization investment portfolio for BPKH based on PP No.5 Tahun 2018.Methodology – The data used in this study was quarterly in the form of price and coupon for Sukuk instruments and the equivalent of yield rate for Sharia deposits. This study uses the Markowitz Diversification method with the Tangency Portfolio model as a model to determine optimal portfolio. Findings – The result of this study showed that BPKH’s actual portfolios in 2018 and 2019 can’t be determined as efficient portfolios and the optimal portfolio. Meanwhile, BPKH’s actual portfolios in 2020 and 2021 are included as efficient portfolios but not optimal portfolio. The result of an optimal portfolio in this study has a composition as follows: 30% of Sharia deposits, 5,60% of SBSN, and 64,40% of SDHI.Implication – The finding of an optimal portfolio can recommend BPKH to allocate most of the hajj fund in SDHI than SBSN because the SBSN has high risk and still to allocate in Sharia deposits as worth maximum based on regulation in PP No.5 Tahun 2018. BPKH needs to diversify hajj fund investment wider such as Lembaga Tabung Haji (LTH) has done in Malaysia.Originality – This study contributes to evaluate of whether BPKH’s actual portfolios in the first third years since BPKH operation and after the first third years of BPKH operation are efficient and optimal or not. Furthermore, this study provides a combination of instruments in the scenario optimal portfolio.
Christianity, ‘supernatural’ beliefs and COVID-19

COVID-19 arguably had far-reaching implications for Christianity and the church as an institution. Issues around social distancing and lockdown directly impacted articulation and religious expression, while understanding of the pandemic and the virus were mediated through constructions of religio-spiritual beliefs. Given this, the study sought to explore some neo-Pentecostal church leaders’ messages in South Africa regarding the novel coronavirus or COVID-19, what this meant to their followers and the associated implications for the spread and effects of COVID-19. Methodologically, the researcher iewed and listened to uploaded YouTube video clips of news related to the church and COVID-19, uploaded bymedia outlets and the neo-Pentecostal church leaders themselves as well as online newspaper reports from the period 2 March to 19 June 2020. The findings of the study reveal that neo-Pentecostal church leaders attributed the origins of SARS-COV-2 to “evil” spirits. Neo-Pentecostal church leaders had mixed messages on the possible cure for COVID-19, with some emphasising miracles as the panacea for COVID-19, and a minority believing that God exhibits his power through epidemiologists. Prayer was also viewed as a tool for Christians to protect themselves from contracting COVID-19 through the invocation of divine powers. The paper concludes that the pervasive influence of church leaders and their emphasis onspiritual remedies such as prayer and miracles may have given Pentecostal followers a false sense of security, which might have affected their awareness of COVID-19.
The Relationship Between Family Support And Quality of Life of Cervical Cancer Patients in Rumah Singgah Sasana Marsudi Husada Indonesia

Introduction: Patients with cervical cancer are in need of support from people around them, especially families, sometimes they need hospital treatment also required encouragement and motivation of family members to reduce psychological burden and quality of life of patients with cancer increases. The purpose of this research is to determine the relationship between family support and quality of life of cervical cancer patient at Rumah Singgah Sasana Marsudi Husada Yayasan Kanker Indonesia (YKI), East Java, Indonesia. Methods: The research design used correlation analysis with cross sectional study design. Thirty patients with cervical cancer were involved through purposive sampling technique. The independent variable was family support and dependent variable was quality of life. The instrument used in this research was the WHOQOL-BREF questionnaire. The data were analyzed by Spearman Rank (Rho) test with α < 0.05. Results: Statistical result showed that family support significantly relate to quality of life of cervical cancer patient with a value of p = 0,000 and correlation coefficient (r) = 0,994 which means it has a strong relationship. Conclusion: There is a positive and strong relationship between family support and the quality of life of cervical cancer patients. The higher the family support, the better the quality of life felt by cervical cancer patient. All staffs of the institution or foundation is expected to encourage families to support and care for sick family members (cervical cancer patient). Thus, health workers must also enhance their knowledge and skills to detect any changes in the life situation (especially family support) experienced by cancer patients, because this will affect their quality of life.