Miracle-dz/UniFAR-FTUs huggingface dataset:
Efficient photocatalytic hydrogen evolution over Ptx-/TiO2-yBy catalysts in a ternary system of K+, Mg2+/B4O72 /H2O

In this study, a novel photocatalyst, Ptx-/TiO2-yBy, is prepared by impregnation of a B4O72- anion solution coupled with a new type of water splitting system for hydrogen evolution. The results show that the B4O72- anion solution is a very good system for B-doping Pt/TiO2 photocatalyst preparation. The particular advantages of this preparation method are that the incorporation of B into Pt/TiO2 can be achieved via coupling with the photocatalytic reaction and that the doping of B into photocatalyst Pt/TiO2 results in the negative shift of Pt binding energy and the efficient reduction of H+ to H2, even though no sacrificial electron donor existed. In the study of photocatalysis, it is found that the B4O72- anion solution is a newly efficient water splitting environment. The rate of hydrogen evolution increases with addition of B4O72- anion. On the basis of the studies of photoelectrochemical properties in this system, the interesting phenomenon is found that interval illumination may enhance the rate of hy.
Prevalence of Congenital Heart Disease among Children in Khorramabad (West of Iran).

AIMS Congenital heart disease is among the most common congenital anomalies in pediatrics. The aim of this study was to evaluate the prevalence of congenital heart disease in children in Khorramabad, Iran. METHODS This is a descriptive-cross sectional study where all the children admitted to Shahid Madani Hospital who were diagnosed with congenital heart disease by echocardiography were enrolled. Patient information was collected by means of a questionnaire. Of 1600 children who underwent cardiac counseling, 9.75% presented congenital heart disease. These were most prevalent among the children of 0-28 days of the age (14.7%) and least in children aged 1 month-1year. According to this study, atrial (20.3%) and ventricular septal defect (10.5%) were the most common heart defects, respectively. Among signs and symptoms of cardiac disease, 49.1% of children had cyanosis, 89.7% with increased CT (cardiothoracic)-ratio, and 82.7% of had heart murmur. Congenital heart disease was more prevalent in male infants (58%) and 6.6% patients had heart failure and 1.4% had other congenital conditions, such as Down syndrome. RESULTS According to our findings, atrial and ventricular septal defects are the most common congenital heart anomalies, respectively, in pediatric patients in Khorramabad.
Synthesis, crystal structure and solid state NLO properties of a new chiral bis(salicylaldiminato)nickel(II) Schiff-base complex in a nearly optimized solid state environment

A new chiral ligand based on the condensation of 4-diethylaminosalicylaldehyde with (1R,2R)-(+)-1,2-diphenylethylenediamine (H2L2) is reported along with its nickel(II) complex. The diamagnetic NiL2 complex exhibits an efficiency 13 times that of urea in second harmonic generation at 1.9 µm. The structure–property relationships are discussed on the basis of the crystal structure, in relation with that of a previously reported derivative which possesses the same molecular NLO response, but very different crystal structure.
The goal-control model: An integrated neuropsychological framework to explain impaired performance of everyday activities.

OBJECTIVE This review describes the relatively small body of neuropsychological and cognitive research conducted over the past 100 years focused on theoretical models explaining the neurocognitive processes that support everyday functioning and the breakdown of functional abilities in the face of neurological damage or disease. METHOD The historical roots of the theories of everyday activities based on direct observation of behavior in neurology and diary reports of everyday errors in cognitive psychology are presented, followed by a review of the empirical findings and resulting theoretical conceptualizations from case studies and group studies of various clinical populations in neuropsychology. RESULTS We conclude with a new framework (the goal-control model) that integrates the most recent empirical findings in neuropsychology with mechanisms proposed by cognitive models. CONCLUSIONS The goal-control model offers empirically supported solutions to understanding and predicting functioning in the real world. This new model generates testable predictions for future research and provides guidance for clinical assessment and interventions. (PsycInfo Database Record (c) 2021 APA, all rights reserved).
A Systematic Review of the MDMA Model to Address Social Impairment in Autism

Background Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder characterised by repetitive behaviours, cognitive rigidity/inflexibility, and social-affective impairment. Unfortunately, no gold-standard treatments exist to alleviate the core socio-behavioural impairments of ASD. Meanwhile, the prosocial empathogen/entactogen 3,4-methylene-dioxy-methamphetamine (MDMA) is known to enhance sociability and empathy in both humans and animal models of psychological disorders. Objective We review the evidence obtained from behavioural tests across the current literature, showing how MDMA can induce prosocial effects in animals and humans, where controlled experiments were able to be performed. Methods Six electronic databases were consulted. The search strategy was tailored to each database. Only English-language papers were reviewed. Behaviours not screened in this review may have affected the core ASD behaviours studied. Molecular analogues of MDMA have not been investigated. Results We find that the social impairments may potentially be alleviated by postnatal administration of MDMA producing prosocial behaviours in mostly the animal model. Conclusion MDMA and/or MDMA-like molecules appear to be an effective pharmacological treatment for the social impairments of autism, at least in animal models. Notably, clinical trials based on MDMA use are now in progress. Nevertheless, larger and more extended clinical studies are warranted to prove the assumption that MDMA and MDMA-like molecules have a role in the management of the social impairments of autism.
Study Design and Participants’ Profile in the Sub-Cohort Study in the Japan Environment and Children’s Study (JECS)

Background The Japan Environment and Children’s Study (JECS) is a nationwide birth cohort study investigating environmental effects on children’s health and development. A Sub-Cohort Study has begun, conducting extended exposure and outcome measurements by targeting a subgroup randomly selected from the JECS Main Study. We report the Sub-Cohort Study methodology and participants’ baseline profiles. Methods Of 100,148 children in the JECS Main Study, children born after April 1, 2013 who met eligibility criteria ([1] all questionnaire and medical record data from children and their mothers collected from the first trimester to 6 months of age, [2] biospecimens [except umbilical cord blood] from children and their mothers collected at first to second/third trimester and delivery) were randomly selected for each Regional Centre at regular intervals. Face-to-face assessment of neuropsychiatric development, body measurement, paediatrician’s examination, blood/urine collection for clinical testing and chemical analysis, and home visits (ambient and indoor air measurement and dust collection) are conducted. Participants are followed up at 1.5 and 3 years old for home visits, and 2, 4, 6, and 8 years old for developmental/medical examination. The details of protocols after age 10 are under discussion. Results Of 10,302 selected children, 5,017 participated. The profiles of the participating mothers, fathers and children did not substantially differ between the Main Study and Sub-Cohort Study. Conclusion The JECS Sub-Cohort Study offers a platform for investigating associations between environmental exposure and outcomes.
Porphyromonas gingivalis lipopolysaccharide (Pg-LPS) influences adipocytes injuries through triggering XBP1 and activating mitochondria-mediated apoptosis

ABSTRACT Obesity is an important public-health problem worldwide. This study aimed to determine effects of porphyromonas gingivalis lipopolysaccharide (Pg-LPS) on adipocytes injuries and explore associated mechanisms. Adipocytes were isolated from SD rats. pLVX-XBP1 (XBP1 over-expression) and pLVX-XBP1-RNAi (silencing XBP1) were structured and transfected into adipocytes. All adipocytes were divided into pLVX-NC, pLVX-XBP1, pLVX-NC+Pg-LPS and pLVX-XBP1+ Pg-LPS group. Oil-Red O staining was employed to identify isolated adipocytes. Quantitative real-time PCR (qRT-PCR) was used to examine gene transcription of IL-6, TNF-α, leptin, adiponectin. Western blotting was used to detect Bax and caspase-3 expression. Adipocytes were successfully isolated and identified with Oil-Red O staining. Both XBP1 mimic and XBP1 RNAi were effectively transfected into adipocytes with higher expressing efficacy. XBP1 over-expression significantly aggravated Pg-LPS induced inflammatory response compared to adipocytes without Pg-LPS treatment (p<0.05). Pg-LPS significantly enhanced leptin and inhibited adiponectin expression by up-regulating XBP1 expression (p<0.05). XBP1 silence significantly alleviated Pg-LPS induced inflammatory response and reduced leptin, enhanced adiponectin expression in Pg-LPS treated adipocytes compared to adipocytes without Pg-LPS treatment (p<0.05). Pg-LPS induced apoptosis of adipocytes by enhancing XBP1 expression and modulating Bcl-2/Bax pathway associated molecules. In conclusion, Porphyromonas gingivalis lipopolysaccharide (Pg-LPS) induces adipocytes injuries through modulating XBP1 expression and initialling mitochondria-mediated apoptosis.
Leaching of Iron-Containing Copper-Nickel Matte at Atmospheric Pressure

Abstract Technology is developed and demonstrated at plant scale 'for leaching high iron (>0.5 %) Ni-Cu matte with spent copper sulfate tankhouse electrolyte at atmospheric pressure to solubilize over half of the matte's nickel values while maintaining near complete rejection of the electrolyte's acid, copper and iron content. The higher the ratio of acid-to-copper in the electrolyte feed, the easier copper is to reject; nickel extraction is maximized. The reverse is true with regard to iron precipitation. When sulfur content of the matte is decreased, copper rejection accelerates; iron removal becomes more difficult. High reaction temperature (90°C) retards iron rejection; low temperature facilitates iron rejection. Copper behaves in the opposite manner. Resume On a developpe et mis a l'epreuve en usine une technique de lixiviation d'une matte de nickel-cuivre a haute teneur en fer (>0.5%); on utilise a cette fin le residu industriel de l'electrolyse d'une solution de sulfate de cuivre. La lixiviation se.
Two Cases of Severe COVID-19 Pneumonia Effectively Treated with Extracorporeal Membrane Oxygenation in Addition to Favipiravir and Corticosteroid

Case 1: A 65-year-old man with novel coronavirus infection (COVID-19) complicated with acute respiratory failure. On admission, the patient was started on favipiravir and corticosteroid. However, due to a lack of significant improvement, he was introduced to mechanical ventilation and extracorporeal membrane oxygenation (ECMO). Although iliopsoas hematoma occurred as a complication, the patient recovered. Case 2: A 49-year-old man with COVID-19 had been started on favipiravir and corticosteroid. Due to progressive respiratory failure, the patient underwent mechanical ventilation and ECMO. The patient recovered without complications. We successfully treated these severe cases with a multimodal combination of pharmacological and non-pharmacological supportive therapy.
The potential role of leukoaraiosis in remodeling the brain network to buffer cognitive decline: a Leukoaraiosis And Disability study from Alzheimer's Disease Neuroimaging Initiative.

Background Leukoaraiosis (LA) is a phenomenon of the brain that is often observed in elderly people. However, little is known about the role of LA in cognitive impairment in neurodegeneration and disease. This cross-sectional, retrospective Leukoaraiosis And Disability (LADIS) study aimed to characterize the relationship between brain white matter connectivity properties with LA ratings in patients with Alzheimer's disease (AD) as compared with age-matched cognitively normal controls. Methods Patients with AD (n=76) and elderly individuals with normal cognitive (NC) function (n=82) were classified into 3 groups, LA1, LA2, and LA3, according to the rating of their white matter changes (WMCs). Diffusion tensor imaging (DTI) data were analyzed by quantifying and comparing the white matter connectivity properties and gray matter (GM) volume of brain regions of interest (ROIs). Results The rich-club network properties in the AD LA1 and LA2 groups showed significant patterns of disrupted peripheral regions and reduced connectivity compared to those in the NC LA1 and LA2 groups, respectively. However, the rich-club network properties in the AD LA3 group showed similar patterns of disrupted peripheral regions and reduced connectivity compared to those in the NC LA3 group, despite there being significant hippocampal and amygdala atrophic differences between AD patients and NC elders. Compared to the NC LA1 group, the characteristic path length of white matter fiber connectivity in the NC LA3 group was significantly increased, and the brain's global efficiency, clustering coefficient, and network connectivity strength were significantly reduced (P<0.05, respectively). However, no significant differences (P>0.05) were observed in characteristic path length, reduced global efficiency, or the clustering coefficient between the NC LA3 and AD LA1 groups, or between the NC LA3 and AD LA2 groups. Conclusions Our findings offer some insights into a potential role of LA in cognitive impairment that may predict the development of disability in older adults. The occurrence of LA, an intermediate degenerative change, during neurodegeneration and disease may potentially lead to the remodeling of the brain network through brain plasticity. LA, therefore, representing a possible compensatory mechanism to buffer cognitive decline.
Repellency of Tribolium castaneum Herbst and Tribolium confusum Duval (Coleoptera : Tenebrionidae) to the Rhizome and Leaf Extracts of Zingiber cassumunar Roxb.

Repellent activity of different solvent extracts of Zingiber cassumunar rhizome and leaf against Tribolium castaneum and T. confusum were conducted. The results indicated that both the insect species were repelled by Z. cassumunar rhizome and leaf extracts. Among these, acetone extracts of rhizome showed highest repellency to T. castaneum than those of other extract tested. Petroleum ether extracts of Z. cassumunar leaf acted as repulsive to T. castaneum whereas other extracts exhibited weak to moderate effects to the beetles. All the extracts of leaf produced weak to moderate effects to T. confusum however, methanol extract of leaf showed little effect to the bettles. Key words: Zingiber cassumunar , Seed and leaf extracts, Repellency, Tribolium castaneum , T. confusum. DOI: 10.3329/bjsir.v43i2. 969 Bangladesh J. Sci. Ind. Res. 43(2), 251-258, 2008
Caracterização química, físico-quimica e sensorial de geleias mistas de açai (Euterpe oleracea) e mel de cacau (Theobroma cacao)

Four formulations of mixed acai (Euterpe oleracea) (A) and cocoa´s honey (Theobroma cacao) (CH) jellies were prepared according to the following proportions: T1 (40% A:60% CH), T2 (50% A:50% CH), T3 (60% A: 40% CH) and T4 (100% A - control). All formulations were prepared using a rate 60:40 (w/w) of sucrose and pulp, plus 0.5% pectin and the products reached to average of 65% soluble solids content. The jellies were analyzed by chemical and physicochemical (titratable acidity, pH, soluble solid content, dry matter, total protein, lipids, vitamin C and calories) and sensory characteristics; also were evaluated levels of P, K, Ca, Mg, Fe, Zn, Cu and Mn. It was used a hedonic scale of 7 points to evaluate the attributes: overall impression, spreadability, brightness, flavor, texture and color, and also was verified the purchase intention score. The titratable acidity and pH ranged from 0.46 to 0.64% and 3.35 to 3.64, respectively, that are within the range found at most fruit jellies. The soluble solids content ranged between 65.2 and 65.5 oBrix. The sensory acceptance results showed that all treatments (T1, T2, T3 and T4) presented means of sensory attributes above 4, demonstrating good acceptance of the product, but the treatment T1 presented the higher scores for the evaluated attributes. Cocoa´s honey added a positive influence on the attributes of color, texture and spreadability.
Investigation of the influence of Ceratophyllum demersum to refine diluted compost latex

Water pollution has always been a major problem in the environment. Polluted water is harming for human health and need to clean water from pollution factors. One of the economic and rapid methods for elements removal is displacement metals by biosorption. The purpose of this study was refining diluted compost latex by Ceratophyllum demersum that was diluted 200 times with distilled water. Diluted compost latex (DCL) accompany with aquatic plant Ceratophyllum demersum was located in bottles which were 6 liter in four replication. The experimental performed at the open air of Khorasgan (Isfahan, Iran) University area for 18 days without aeration. Result of Chemical oxygen demand (COD) indicates that the COD was decreased from 728 mg/L to 189.5 mg/L. Also, this investigation was demonstrated that the amount of ammonium in diluted compost latex was decreased from 60 meq/L to 13.33 meq/L. The amount of nitrate in diluted compost latex has decreased from 90 meq/L to 26.66 meq/L, and the amount of Phosphorous was declined from 1.2 meq/L to 0.21 meq/L. EC of diluted compost latex was reduced from 1.02 ds/m to 0.74 ds/m. All of the consequences which were mentioned indicated that this aquatic plant (Ceratophyllum demersum) is one of the best natural ways to refine Polluted water.
EFFECT OF ETHANOL CONTENT ON MASS-TRANSFER PARAMETERS AND HETP INDEXES OF AMINO ACIDS IN A POLY-4-VINYLPYRIDINE CHROMATOGRAPHY

A series of fundamental tasks required for the development of a solvent gradient simulated moving bed (SG-SMB) chromatography for amino acid separation were performed in this study. First, the mass-transfer parameters of amino acids in the chromatographic column packed with poly-4-vinylpyridine resin (i.e., the adsorbent of the SG-SMB) were estimated while varying the content of ethanol in the mobile phase. Then, the effect of ethanol content on the mass-transfer parameters of amino acids was analyzed. To describe the effect in a quantitative or a mathematical manner, proper mass-transfer equations were developed and the related parameter values were determined. The developed mass-transfer equations and the determined parameter values were validated with experimental chromatogram data, and they will be highly useful in the stage of designing the SG-SMB because they can be incorporated into the model equations of the SG-SMB. Furthermore, the HETP (Height Equivalent to a Theoretical Plate) indexes of amino acids were evaluated while varying ethanol content and liquid velocity. The results showed that an increase in the ethanol content led to an increase in the HETP on the whole. In addition, the intra-particle diffusion was found to become a controlling factor in the HETP as the liquid velocity increased. The results of this study will be of great value in the stage of developing the SG-SMB chromatography for amino acid separation.
Drug‐induced psoriasiform alopecia associated with interleukin‐17 inhibitor therapy

Drug‐induced psoriasiform alopecia is an increasingly recognized form of alopecia mostly reported in association with TNF‐alpha inhibitors. However, drug‐induced psoriasiform alopecia in association with IL‐17A inhibitors has not been described. We present a 62‐year‐old woman with severe psoriasis who developed new psoriatic plaques on the scalp with alopecia after initiating ixekizumab (anti‐IL‐17A). Scalp biopsy specimens revealed a non‐cicatricial alopecia with increased telogen/catagen follicles, atrophy of the sebaceous glands, peribulbar and perifollicular inflammation with frequent lymphocytes, plasma cells, eosinophils, psoriasiform dermatitis, and lack of intra‐corneal or intra‐epidermal neutrophils. Overall, the clinical and histopathologic findings were most compatible with a drug‐induced psoriasiform alopecia in association with IL‐17A inhibitor therapy. Our case shows that drug‐induced psoriasiform alopecia can paradoxically occur in patients on IL‐17A inhibitor therapy and contributes to the growing list of cutaneous eruptions associated with biologic agents.
Human adipose‐derived stromal/stem cells are distinct from dermal fibroblasts as evaluated by biological characterization and RNA sequencing

Human adipose‐derived stromal/stem cells (ASC) have immunomodulatory properties and the potential to differentiate into several cell lines, important for application in regenerative medicine. However, the contamination with dermal fibroblasts (FIB) can impair the beneficial effects of ASC in cell therapy. It is then essential to develop new strategies that contribute to the distinction between these two cell types. In this study, we performed functional assays, high‐throughput RNA sequencing (RNA‐Seq) and quantitative PCR (qPCR) to find new markers that can distinguish ASC and FIB. We showed that ASC have adipogenic and osteogenic differentiation capacity and alkaline phosphatase activity, not observed in FIB. Gene expression variation analysis identified more than 2000 differentially expressed genes (DEG) between these two cell types. We validated 16 genes present in the list of DEG, including the alkaline phosphatase gene (ALPL). In conclusion, we showed that ASC and FIB have distinct biological properties as demonstrated by alkaline phosphatase activity and differentiation capacity, besides having different gene expression profiles.
Small-angle scattering from polydisperse particles with a diffusive surface

Particles with a diffusive surface, characterized by a deviation from the Porod power-law asymptotic behavior in small-angle scattering towards an exponent below −4, are considered with respect to the polydispersity problem. The case of low diffusivity is emphasized, which allows the description of the scattering length density distribution within spherically isotropic particles in terms of a continuous profile. This significantly simplifies the analysis of the particle-size distribution function, as well as the change in the scattering invariants under contrast variation. The effect of the solvent scattering contribution on the apparent exponent value in power-law-type scattering and related restrictions in the analysis of the scattering curves are discussed. The principal features and possibilities of the developed approach are illustrated in the treatment of experimental small-angle neutron scattering data from liquid dispersions of detonation nanodiamond. The obtained scattering length density profile of the particles fits well with a transition of the diamond states of carbon inside the crystallites to graphite-like states at the surface, and it is possible to combine the diffusive properties of the surface with the experimental shift of the mean scattering length density of the particles compared with that of pure diamond. The moments of the particle-size distribution are derived and analyzed in terms of the lognormal approximation.