Miracle-dz/UniFAR-FTUs huggingface dataset:
Clinicopathological features of breast cancer cases and their relationship with immunohistochemical findings

Aim: To determine the relationship between established prognostic markers and Ki67 proliferative index in breast cancer patients and investigate variations of prognostic parameters between material types (tru-cut biopsy or resection). Material and Methods: Breast cancer cases reported in our laboratory between July 2015 and December 2019, as well as estrogen receptor (ER), progesterone receptor (PR), CerbB2, Ki-67 staining results, tumor type, histologic grade, tumor size, lymph node metastasis status parameters were obtained from the automation system. Tru-cut biopsy and resection materials were evaluated and the parameters were compared. Results: 726 materials taken from 571 adult patients were included in this study. 297 (40.9%) of the cases were evaluated by tru-cut biopsy and 430 (59.1%) were resection material. The mean ER staining percentage was 86.5 (± 10.36) and it was 61.65 (± 22.84) for PR. Ki-67 proliferative index had an average value of 26.58 (± 17.67). There was no difference between the material types in terms of immunohistochemical markers, whereas there were differences between the two material types in histological grade results. Conclusion: Besides established immunohistochemical prognostic markers, Ki67 proliferative index should be utilized in breast cancer cases and determination of histological grade in tru-cut biopsies is valuable for the clinical management of the tumor.
Structure and Evolution of Legislation Networks

Laws have unique features that evolve in response to societies and environments. A full description of the complex legislation networks that underlie law-specific functions is still missing. We describe a document-document interaction map for the legislation network of New Zealand containing about 138000 highly reliable interactions between about 16000 laws. In this study, the global behaviour of legislation evolution emerges from statistical analyses of the resulting network, together with a novel stochastic model to explain the network generative processes. We observe a dynamic growth pattern of individual laws’ in-degree, providing evidence for a model of evolution for legislation networks. This and future legislation network evolution models should facilitate systematic approaches to understand legislative processes better and improve them. Our proposed information extraction framework generates reliable dynamic networks of legislation by recognising distinct expressions in legal texts. We note the importance of data accuracy in network analysis and improved approximate string matching techniques. We demonstrate network data-sets with more than 98 percent precision and recall. The linear growth in legislation network size reflects a fixed capacity for parliament to pass laws. Also, the exponential growth in their density explains improvements in the law drafting processes. The preferential attachment process for legislation is impacted as a result of node aging, node capacity in receiving new edges, and content limitations. Thus legislation networks don’t show scale-free power-law properties. Our stochastic model of the legislation network evolution process explains their broad-scale to single-scale behaviour with a Lomax distribution.
Non-thermal plasmas in and in contact with liquids

During the last two decades atmospheric (or high) pressure non-thermal plasmas in and in contact with liquids have received a lot of attention in view of their considerable environmental and medical applications. The simultaneous generation of intense UV radiation, shock waves and active radicals makes these discharges particularly suitable for decontamination, sterilization and purification purposes. This paper reviews the current status of research on atmospheric pressure non-thermal discharges in and in contact with liquids. The emphasis is on their generation mechanisms and their physical characteristics.
Bacterial inoculation: A tool for red clover growth promotion in polluted soil

Red clover (Trifolium pratense L.) seeds were inoculated with several plant growth-promoting bacteria (PGPB) and sown in the substrate contaminated with polycyclic aromatic hydrocarbons (PAHs), polychlorinated biphenyls (PCBs) and organometallic derivatives of tin (OT). The aim was to determine if selected PGPB strains can promote the growth of red clover in the substrate contaminated with several organic pollutants. The influence of bacteria on red clover growth (height, root length and biomass) was monitored during the three-month experimental period. The most significant improvements of seedling height were noted in the treatment with Bacillus amyloliquefaciens D5 ARV and Pseudomonas putida P1 ARV. Root growth was positively affected by Serratia liquefaciens Z-I ARV. The same isolates significantly affected biomass production. Those isolates caused total biomass increases of 70%, 48% and 33% compared to control. Bacterial strains used in this study were already confirmed as PGPB by biochemical testing, as well as by an in vivo test of mixed inoculums on several woody plants grown in the coal-mine overburden site. This work is the first-time record on their individual effects on one plant species. Obtained results confirmed that inoculation with several PGPB strains can enhance red clover growth in polluted soil.
Source water variability as a driver of rockfish recruitment in the California Current Ecosystem: implications for climate change and fisheries management

Elucidating connections between ocean climate variability and change and recruitment of juvenile fishes to adult populations is critical for understanding variability in stock–recruit dynamics. Recruitment to adult rockfish populations in the California Current Ecosystem (CCE) is highly variable, leading to short- and long-term changes in abundance, productivity, forage availability, and potential fisheries yield. We used regional ocean model output, oceanographic data, and a 34-year time series of pelagic juvenile rockfish to investigate the interaction between changes in CCE source waters, as reflected by physical water mass properties, and recruitment variability. Specifically, variability of “spiciness” on upper water isopycnals explains a substantial fraction of the variation in pelagic juvenile rockfish abundance. High rockfish abundances correspond to cooler, fresher waters with higher dissolved oxygen (i.e., “minty”) conditions, indicative of Pacific subarctic water. By contrast, years of low rockfish abundance are associated with warmer, more saline, and more oxygen-deficient (i.e., “spicy”) conditions, reflecting waters of subtropical or equatorial origin. Transport and source waters in the CCE are key factors determining density-independent processes and subsequent recruitment to adult populations.
Impact of planting distance and bio-fertilizers on growth and yield attributes of turnip (Brassica rapa L.) cv. Pusa Sweti under Garhwal hills

A field experiment was conducted during Rabi season 2017-18 at Horticultural Research Centre, Chauras Campus, H.N.B. Garhwal University, Srinagar (Garhwal), Uttarakhand to find out the combined effect of planting distance and bio-fertilizers on growth and yield of turnip under sub-tropical condition of Garhwal Himalaya. Nine treatment combinations were investigated. Treatments comprises three different planting distance: S1 (10 cm x 40 cm), S2 (15 cm x 40 cm) and S3 (20 cm x 40 cm)), three biofertilizer: B1 (Azotobacter), B2 (Azospirillum) and B3 (Control) in Factorial Randomized Block Design with three replications. Results revealed that the planting distance and biofertilizers significantly influenced the growth and yield attributing characteristics. The treatment combination S3B1 (40 cm x 20 cm with Azotobactor) was found superior all other treatments in relation to growth and yield attributes of turnip.
Initial COVID Hydroxychloroquine Failure Responds to Interferon and Tocilizumab - Inflammation and Cardiovascular Disease FMTVDM CoViD Proposed Treatment Protocol.

Currently there is no established treatment protocol for SARS-2 (CoVid-19). Proponents of hydroxychloroquine (HCQ) argue that early intervention may sufficiently prevent replication of the virus and avoid the need for hospitalization. In instances where viral replication continues and the patient develops CoViD pneumonia (CVP), such patients – particularly with comorbidities – are prone to develop an InflammoThrombotic response similar to cytokine release syndrome (CRS). We present one such patient who failed HCQ treatment and was subsequently treated successfully with an interleukin-6 inhibitor and interferon.
The Importance of Deposit Insurance Credibility

The success of deposit insurance arrangements at eliminating bank runs is likely closely tied to their credibility. We investigate this hypothesis building on two episodes which tested the insurance protection offered by the Portuguese arrangement in the midst of the country’s sovereign debt crisis. Our results show that Portuguese depositors responded to foreign banks’ decision to convert their subsidiaries into branches by relocating their deposits into the latter. We find a similar response following the announcement that insured depositors in Cyprus would lose part of their savings. On both instances responses are concentrated on household deposits. Given that foreign banks’ branches offer the insurance protection of these banks’ home countries, rather than that granted by their host country arrangement, our findings confirm that the credibility of the deposit insurance arrangement is critical for the protection it offers banks against the risk of depositor runs. These results show that sovereign-bank links can be detrimental to financial stability through a novel channel: the credibility of deposit insurance.
Power-Efficient Noise-Induced Reduction of ReRAM Cell’s Temporal Variability Effects

Resistive Random Access Memory (ReRAM) is a promising novel memory technology for non-volatile storing, with low-power operation and ultra-high area density. However, ReRAM memories still face issues through commercialization, mainly owing to the fact that the high fabrication variations and the stochastic switching of the manufactured ReRAM devices cause high Bit Error Rate (BER). Given that ReRAM devices are nonlinear elements, the nonlinear phenomenon of Stochastic Resonance (SR), which defines that an input disturbance with specific characteristics can improve the total performance of the nonlinear system, is used to reduce the ReRAM cell’s BER. Thus, in this brief, the BER of a single ReRAM cell is explored, using the Stanford PKU model, and is improved after the application of specific additive input noise. The power dissipation of the proposed approach is also evaluated and compared with the consideration of higher amplitude writing pulses in the lack of noise, showing that the proposed noise-induced technique can decrease the BER without the excessive increase of the power dissipation. As a first step, towards the experimental verification of the proposed method, noise-induced measurements on a single fabricated ReRAM device are also performed. Overall, the presented results of the BER reduction with low power dissipation, reaching up to $3.26\times $ less power consumption considering 100 ns writing pulses, are encouraging for ReRAM designers, delivering a circuit-level solution against the device-level problem.
Two interesting phenomena observed in the axial power distribution of a BWR

Two interesting phenomena were observed in the axial power distribution in the core of the Japan Power Demonstration Reactor. One is the control-rod and void coupled bump on the axial power shape; this is a kind of local power peaking produced by the interacted effect between the partially inserted control rod and the axial void changes in the moderator. The other may be termed a burnup oscillation of the axial power distribution''; this is a long-term, periodic change of the axial power distribution due to core exposure and to the withdrawal of the control rods. It is found that the upper and lower half-channel integrations of the local leakage of thermal neutrons are essential factors for the occurrence of those phenomena. 9 references. (auth)
First report of southern root-knot nematode, Meloidogyne incognita, infecting Brassica nigra in Peru

Abstract Brassica nigra plants showing symptoms caused by root-knot nematodes were detected in the municipality of La Joya, Arequipa Province, Peru. Based on morphology, esterase phenotypes, and species-specific characterized amplified region (SCAR) sequence, the causal agent was identified as Meloidogyne incognita. Pathogenicity was confirmed by a modified version of Koch’s postulates. To our knowledge, this is the first report of M. incognita infecting Brassica nigra in Peru.
Modelo estructural de concurrencia entre bullying y cyberbullying: víctimas, agresores y espectadores / Structural Model of Concurrence Among Relational Bullying and Cyberbullying: Victims, Aggressors and Bystanders

espanolEste estudio analiza las percepciones de n. = 4.273 estudiantes de secundaria de Aragon (Espana) sobre el bullying relacional y el cyberbullying desde diferentes perspectivas: victimas, agresores y espectadores, para explorar la posible concurrencia entre ambos tipos de violencia escolar. Se analizo un modelo estructural entre ambos tipos de violencia, obteniendo un ajuste optimo. Este modelo desarrollado entre el bullying relacional y el cyberbullying representa un avance significativo al incluir perspectivas no solo del agresor y la victima, sino tambien del espectador. Los resultados indican que el acoso tradicional se prolonga en el ciberacoso. Tanto los agresores como las victimas de bullying estan relacionados con ser espectadores de cyberbullying. Sobre el cyberbullying, el espectador puede ser victima o agresor que copia los dos modelos, derivados de esa observacion. EnglishThis study analyses the perceptions of n. = 4,273 high school students in the Spanish region of Aragon about relational bullying and cyberbullying from different perspectives, those of victims, aggressors and bystanders, to explore the possible concurrence between both types of bullying. A structural model of the concurrence between both types of violence was analysed, obtaining an optimal fit. This model of both relational bullying and cyberbullying represents a significant advance by including perspectives not only of aggressors and victims, but also those of bystanders. Results indicate that traditional bullying extends to cyberbullying among those involved: Both aggressors and victims of relational bullying are often bystanders of cyberbullying. Regarding the latter, the bystander in this type of violence may tend to be a victim or an aggressor in relational bullying who replicates behaviour he or she has seen before.
Inhaled Nitric Oxide: An Experimental Analysis of Continuous Flow Noninvasive Delivery via Nasal Cannula

Inhaled nitric oxide (iNO) is used to treat pulmonary hypertension and improve oxygenation in critically ill patients. It is primarily delivered via mechanical ventilation to patients in the critical care setting; however, there are several drawbacks to this invasive form of delivery. As a result, there has been increased administration of noninvasive delivery in the critical care setting, as well as investigation into long-term noninvasive administration of iNO to treat pulmonary hypertension associated with chronic lung diseases. Dose delivery of iNO is currently defined in terms of the constant concentration that is maintained in the inspired gas although applying this metric for delivery modes other than ventilation is challenging. Dose delivery for iNO supplied at a constant flow rate through a nasal cannula has not yet been established. This thesis aims to determine the influence of nasal cannula type, supply flow rates, and the patient’s breathing pattern on delivered iNO through a nasal cannula. Additionally, a basis for dosage estimation through this delivery mode is provided. This assessment was conducted in vitro using a realistic adult airway replica and lung simulator. The first chapter of this thesis examines and reviews the literature around the applications of iNO and its delivery methods. Chapter 2 examines the theoretical basis for this experimental study of iNO, while the study design and results of experiments are provided in Chapter 3. Chapter 4 summarizes the thesis and provides perspectives for future work.
A Broadband Low-RCS Metasurface for CP Patch Antennas

A novel metasurface (MS)-based method for broadband radar cross section (RCS) reduction of circularly polarized (CP) patch antennas is proposed. The RCS reduction is achieved in a much broader band than the operational band of the antenna. The simple technique is based on MS units on a grounded substrate in a checkerboard-like configuration. The broadband RCS reduction is achieved by combining two different destructive interference principles. In the high-frequency region, for a normal incident wave, the RCS is reduced by the phase cancellation generated by the MSs and the grounded substrate. In the low-frequency region, the RCS is reduced by the polarization conversion property of the MS. In this case, the fields reflected by two MS sections are in counter phase for a normal incident wave. The MS is combined with a CP patch antenna. It concerns a traditional corner-truncated square patch and four sequentially rotated surrounding MS cells. This dedicated MS allows two things: an additional resonant mode is excited resulting in a 3 dB AR bandwidth extension from 4.2% to 15.9% and a broadband RCS reduction of over 6 dB from 4.95 to 15.73 GHz (104.25% bandwidth) for both <inline-formula> <tex-math notation="LaTeX">$x$ </tex-math></inline-formula>- and <inline-formula> <tex-math notation="LaTeX">$y$ </tex-math></inline-formula>-polarized incident waves.
Human cytomegalovirus is present in the odontogenic epithelium of ameloblastoma

ABSTRACT Background: The factor behind the activation of the remnant odontogenic tissues and development of odontogenic cysts and tumors is poorly understood.This study aimed to investigate the presence of human cytomegalovirus (HCMV) in dentigerous cyst (DC), odontogenic keratocyst (OKC), and ameloblastoma (AB). Methods: The study included 41 samples, which distributed into DC (n=13), OKC (n=12), and AB (n=16). Conventional PCR assay and IHC analysis were used to detect the HCMV-DNA and HCMV glycoprotein B (HCMV-gB) respectively. Results: HCMV-DNA was detected in 10 samples (62.5%) of AB, four samples (30.8%) of DC, and three samples (25 %) of OKC respectively (χ2 test = 1.195, p= 0.247). Meanwhile, HCMV-gB was found in 12 (75%) of AB, in 2 (15.4%) of DC, and absent in OKC (0.0%) (χ2 test = 4.122, p= 0.042). Conclusions: The high prevalence of HCMV inside the odontogenic epithelium of AB could indicate a possible role of the virus in the oncogenesis and/or oncomodulation of the AB. Additionally, we recommend the IHC for the detection of HCMV in the odontogenic tumors like AB.
Perception and Attitudes of Medical Students towards Dermatology
as a Future Specialty, Jeddah, Saudi Arabia.

Background: The distribution of physicians in different specialties across Saudi Arabia is determined by the career choices of medical students. Dermatology residency program is one of the highly competitive programs here in Saudi Arabia. Assessing and understanding the factors perceived to be attractive in choosing dermatology will aid the directors of the specialty programs to plan for a more balanced workforce distribution to better suit the needs of the specialties Aim: The aim of our study is to determine and assess the factors perceived to be significantly attractive when choosing dermatology as a future specialty. Methods: The study is a cross-sectional study conducted in King Saud bin Abdulaziz University for Health Sciences, Jeddah, Saudi Arabia. A validated questionnaire was sent electronically to clinical year medical students. In addition to the questionnaire, gender, GPA, preferred specialty, and other socio-demographic data were assessed. Results: A total of 121 clinical years medical students completed the questionnaire, 8 (6.6%) preferred dermatology as a specialty. 76 (62.8%) of the participants score a GPA of more than 4.5 and 83 students (68.6%) chose their specialty during clinical years. The appeal of being a dermatologist (P= 0.047), the portrayal of different specialities in the media (P= 0.005), and the likelihood that dermatologists can influence patients lives (P=0.010) were shown to be significantly attractive factors. Conclusion: There are many factors that are affecting students choices when choosing a medical specialty. The appeal of being a dermatologist, the portrayal of different specialities in the media, and the likelihood that dermatologists can influence patients lives were shown to be significantly attractive factors when choosing dermatology as a future specialty. Recognizing medical students specialty perception will lead them to a proper specialty tailored to their needs.
Features of Intellectual Functions Inhibition among Ukrainian Boxers: A Sociocultural Study

The effects of boxing’s extreme aggressive conditions in training and competitive activity in sportsmen’s mental working capacity still remains under-explored. While the neurophysiological effects caused by micro traumas to the brain have been extensively studied, less attention has been paid to the psychological consequences. This article reports on our study of the features of mental operations efficiency in Ukrainian boxers. The study involved athletes (n = 168, gender: men, average age: 25.5 ± 6.2 years), who were engaged in boxing and kickboxing in the Ukraine’s eastern region. A ‘Classification’ method was used: a set of 70 cards with the images of various objects, plants, and living beings was given with instructions to arrange the items into groups in such a way that the objects in each concrete group possess common properties. Athletes were divided into groups, depending on the level of their sport qualification. Adopting the Vygotskian perspective, this study shows correlations between the productivity of boxers’ thinking processes and the level of their sport skills: highly qualified sportsmen have many more well-marked thinking process defects than the sportsmen of the 2 nd and 3 rd categories. We observed a decrease in the generalization level, reduction in speed, deterioration of neurodynamic characteristics and criticality processes nearly in all participants. Exhaustibility and decrease in mental working capacity, impulsiveness of thinking, and its unproductive transformation were marked more often among the highly skilled boxers. A discussion on the cultural redefinition of this sport and on the necessary rehabilitative treatments is then presented.