Miracle-dz/UniFAR-FTUs huggingface dataset:
Systematic review and meta-analysis: The association between emotional intelligence and subjective well-being in adolescents.

INTRODUCTION Emotional intelligence (EI) is a psychological protective factor that can improve subjective well-being (WB) in adolescents. This study aims to establish the overall relationship between different EI models (performance-based ability model, self-report ability model, and self-report mixed model) and subjective WB in adolescents, analyze the affective WB and cognitive WB components, and examine the moderating effect of EI models on both types of subjective WB. METHOD We searched PsycINFO and WOS databases. Eligible studies reported an association between EI and subjective WB in adolescents aged 10-19 years using instruments that directly measure subjective WB. In addition, two meta-analyses were conducted, one for the relationship between EI and affective WB and the other for EI and cognitive WB. RESULTS A total of 41 studies were included, of which 37 were pooled in the meta-analyses. We found a significant positive relationship between EI and affective WB (estimated effect size = 0.35) and between EI and cognitive WB (estimated effect size = 0.27). Regarding EI models, self-report ability showed an estimated effect size of 0.33 for affective WB and 0.27 for cognitive WB. For the self-report mixed model, we obtained an estimated effect size of 0.42 for affective WB and 0.37 for cognitive WB. CONCLUSIONS Establishing a quantitative relationship between EI and subjective WB makes it possible to implement clinical and educational prevention measures. Introducing EI training in educational and clinical settings can increase subjective WB, significantly impacting the prevention of emotional disorders in adolescents.
The cellular and molecular mediators of metastasis to the lung

Abstract Organ-specific metastasis to secondary organs is dependent on the formation of a supportive pre-metastatic niche. This tissue-specific microenvironmental response is thought to be mediated by mutational and epigenetic changes to primary tumour cells resulting in altered cross-talk between cell types. This response is augmented through the release of tumour and stromal signalling mediators including cytokines, chemokines, exosomes and growth factors. Although researchers have elucidated some of the cancer-promoting features that are bespoke to organotropic metastasis to the lungs, it remains unclear if these are organ-specific or generic between organs. Understanding the mechanisms that mediate the metastasis-promoting synergy between the host microenvironment, immunity, and pulmonary structures may elucidate predictive, prognostic and therapeutic markers that could be targeted to reduce the metastatic burden of disease. Herein, we give an updated summary of the known cellular and molecular mechanisms that contribute to the formation of the lung pre-metastatic niche and tissue-specific metastasis.
Clinical utility of EBUS‐TBNA of hilar, interlobar, and lobar lymph nodes in patients with primary lung cancer

Endobronchial ultrasound‐guided transbronchial needle aspiration (EBUS‐TBNA) is used to evaluate hilar/interlobar/lobar lymph nodes. This study aimed to assess the clinical utility of EBUS‐TBNA for station 10/11/12 lymph nodes (LNs) in patients with primary lung cancer.
Cancer Effects of Low to Moderate Doses of Ionizing Radiation in Young People with Cancer-Predisposing Conditions: A Systematic Review

Abstract Moderate to high doses of ionizing radiation (IR) are known to increase the risk of cancer, particularly following childhood exposure. Concerns remain regarding risks from lower doses and the role of cancer-predisposing factors (CPF; genetic disorders, immunodeficiency, mutations/variants in DNA damage detection or repair genes) on radiation-induced cancer (RIC) risk. We conducted a systematic review of evidence that CPFs modify RIC risk in young people. Searches were performed in PubMed, Scopus, Web of Science, and EMBASE for epidemiologic studies of cancer risk in humans (<25 years) with a CPF, exposed to low–moderate IR. Risk of bias was considered. Fifteen articles focusing on leukemia, lymphoma, breast, brain, and thyroid cancers were included. We found inadequate evidence that CPFs modify the risk of radiation-induced leukemia, lymphoma, brain/central nervous system, and thyroid cancers and limited evidence that BRCA mutations modify radiation-induced breast cancer risk. Heterogeneity was observed across studies regarding exposure measures, and the numbers of subjects with CPFs other than BRCA mutations were very small. Further studies with more appropriate study designs are needed to elucidate the impact of CPFs on RIC. They should focus either on populations of carriers of specific gene mutations or on common susceptible variants using polygenic risk scores.
Long‐term follow‐up and health‐related quality of life among cancer survivors with stage IEA orbital‐type lymphoma after external photon‐beam radiotherapy: Results from a longitudinal study

We assessed the long‐term outcomes and treatment‐related adverse effects of patients with Stage I, “orbital‐type” lymphomas that were uniformly treated with photons. All consecutive patients diagnosed with low‐grade, Ann Arbor Stage IEA orbital lymphoma treated between 1999 and 2020 at our department were retrospectively reviewed. We excluded patients with exclusive conjunctival involvement, typically treated with en face electrons. In order to quantify radiotherapy related side effects we applied the CTCAE criteria, analyzed changes in visual acuity, quantified dry eye symptoms by use of the Ocular Surface Disease Index (OSDI) score and applied the EORTC QLQ‐C30 questionnaire for quality of life (QoL) assessment. In total 66 eyes of 62 patients were irradiated with a median dose of 30.6 Gy. The median follow‐up was 43.5 months. The predominant histological subtype were MALT lymphomas. No local failure occurred in this cohort. Of nine outfield relapses, six solely occurred in the contralateral eye. The 5‐ and 10‐ years distant progression free survival rates (PFS) were 81.4% and 63.5%. The 5‐ and 10‐years overall survival rates were 85.1% and 71.9% without any tumor related death. Of the acute toxicities none was higher than CTCAE grade 1. The predominant late toxicities were dry eyes (21.2%) of CTCAE Grade <2 and radiation induced cataracts (19.7%). During long‐term follow up the average visual acuity did not deteriorate. The global QoL was worst before treatment and improved significantly after 24 months (p = 0.007). External beam radiotherapy of “orbital‐type” lymphomas with photons is an effective and gentle treatment option with excellent local control rates. From the high control rates the trend to use slightly lower total doses of 24–27 Gy with conventional fractionation is supported. As non‐coplanar radiotherapy techniques improved and total doses can slightly be reduced, the current status of radiotherapy as first line therapy is provided.
CYP4G100 contributes to desiccation resistance by mediating cuticular hydrocarbon synthesis in Bactrocera dorsalis

The oriental fruit fly Bactrocera dorsalis (Hendel) is expanding its distribution to higher latitudes. Our goal in this study was to understand how B. dorsalis adapts to higher latitude environments that are more arid than tropical regions. Cuticular hydrocarbons (CHCs) on the surface of the epicuticle in insects act as a hydrophobic barrier against water loss. The essential decarbonylation reaction in CHC synthesis is catalysed by CYP4G, a cytochrome P450 subfamily protein. Hence, in B. dorsalis it is necessary to clarify the function of the CYP4G gene and its role in desiccation resistance. CYP4G100 was identified in the B. dorsalis genome. The complete open reading frame (ORF) encodes a CYP4 family protein (552 amino acid residues) that has the CYP4G‐specific insertion. This CYP4G gene was highly expressed in adults, especially in the oenocyte‐rich peripheral fat body. The gene can be induced by desiccation treatment, suggesting its role in CHC synthesis and waterproofing. Silencing of CYP4G100 resulted in a decrease of CHC levels and the accumulation of triglycerides. It also increased water loss and resulted in higher desiccation susceptibility. CYP4G100 is involved in hydrocarbon synthesis and contributes to cuticle waterproofing to help B. dorsalis resist desiccation in arid environments.
Correlates of vaping among adolescents in Canada.

Background Vaping is more prevalent among younger than older Canadians. While vaping is less harmful than combustible tobacco, it is not without health risk. Data and methods Data from the 2019 Canadian Health Survey on Children and Youth were used to estimate vaping prevalence. Logistic regression models assessed the association of sociodemographic, youth, parenting and peer factors with vaping. The 2020 Canadian Community Health Survey identified adolescents who reported vaping before tobacco smoking. Data from the 2019 Canadian Tobacco and Nicotine Survey were used to examine vaping of e-liquids containing nicotine and flavours. Results Vaping rates for 15- to 17-year-olds were nearly four times (21.3%) higher than those of 12- to 14-year-olds (5.4%). Two-thirds (66.1%) of 12- to 17-year-olds who had used both tobacco and e-cigarettes reported trying e-cigarettes first. E-liquids containing nicotine were used by 89.3% of 15- to 19-year-olds who reported vaping in the past 30 days; comparable with older adults. For both younger and older adolescents, having friends who engaged in negative behaviours, having been employed, and having consumed alcohol increased the odds. For 12- to 14-year-olds, attention deficit hyperactivity disorder was a risk factor, whereas having parents who usually knew who they were with and higher relatedness scores were protective. Among older adolescents, being male, being Canadian-born, having lower grades, and using tobacco or cannabis increased the odds of vaping. Interpretation An adolescent's risk of vaping was most strongly correlated with other substance use, although other youth, parenting and peer characteristics also mattered. Because most of the data presented were collected before the COVID-19 pandemic and new vaping regulations, ongoing monitoring remains important.
A reappraisal of microbiome dysbiosis during experimental periodontitis".

Periodontitis is a chronic inflammatory disease associated with the presence of dysbiotic microbial communities. Several studies interrogating periodontitis pathogenesis have utilized the murine ligature-induced periodontitis (LIP) model, and have further examined the ligature-associated microbiome relying on 16SrRNA-based sequencing techniques. However, it is often very challenging to compare microbial profiles across studies, due to important differences in bioinformatic processing and databases used for taxonomic assignment. Thus, our study aim was to re-analyze microbiome sequencing data-sets from studies utilizing the LIP model, through a standardized bioinformatic analysis pipeline, generating a comprehensive overview of the microbial dysbiosis during experimental periodontitis. We conducted a re-analysis of 16SrRNA gene sequencing datasets from 9 published studies utilizing the LIP model. Reads were grouped according the hypervariable region of the 16SrRNA gene amplified (V1-V3 and V4), preprocessed, binned into Operational Taxonomical Units (OTUs) and classified utilizing relevant databases. Alpha and beta-diversity analyses were conducted, alongside relative abundance profiling of microbial communities. Our findings revealed similar microbial richness and diversity across studies, and determined shifts in microbial community structure determined by periodontitis induction and study of origin. Clear variations in the relative abundance of bacterial taxa were observed starting day 5 after ligation and onwards, consistent with a distinct microbial composition during health and experimental periodontitis. We also uncovered differentially represented bacterial taxa across studies, dominating periodontal health and LIP-associated communities. Collectively, this re-analysis provides a unified overview of microbial dysbiosis during the LIP model, providing new insights that aim to inform further studies dedicated to unravelling oral host-microbial interactions. This article is protected by copyright. All rights reserved.
How do we reduce the number of missed postpartum diabetes in women with recent gestational diabetes?

data and data weeks(median) delivery prospectively collected. Results : A total of 132(21.8%) women had an abnormal ppOGTT (2.8% impaired fasting glucose(IFG), 13.6% impaired glucose tolerance(IGT), 5.5% Diabetes). Independent risk factors were BMI>30 kg/m 2 (prevalence of abnormal ppOGTT 36.0 vs 17.3%), gestational age(GA) at diagnosis <24 weeks (32.4 vs 18.0%), 1-h-antenatal-value >200 mg/dl(11.1 mmol/L) (35.2 vs 14.8%) and insulin therapy (30.3 vs 14.5%). Prevalence of abnormal ppOGTT was assessed according to the number of risk factors: 0=9.2% (14/153), 1=13.4% (25/186), 2=28.5% (43/151), 3=45.6% (26/57, 4=68.4% (13/19). Subjects were divided according to significant increase of prevalence and risk for ppOGTT: Low risk (59.9% of subjects):<2 RF, 11.6 %, OR 1.3; intermediate:2 RF, 28.5%, OR 4.0 and high:>2 RF, 51.3%, OR 10.5. 86.6% of diabetes and 67% of all abnormal ppOGTTs were identified by the intermediate/high risk group. Conclusion : Women with >2 risk factor have a high risk for abnormal postpartum OGTT, 86% of postpartum diabetes diagnosed within this group. Targeting women for ppOGTT testing on a
ℵ 0 -categoricity of semigroups

In this paper we initiate the study of ℵ 0 -categorical semigroups, where a countable semigroup S is ℵ 0 -categorical if, for any natural number n , the action of its group of automorphisms Aut ( S ) on S n has only ﬁnitely many orbits. We show that ℵ 0 categoricity transfers to certain important substructures such as maximal subgroups and principal factors. We examine the relationship between ℵ 0 -categoricity and a number of semigroup and monoid constructions, namely Brandt semigroups, direct sums, 0-direct unions, semidirect products and P -semigroups. As a corollary, we determine the ℵ 0 -categoricity of an E -unitary inverse semigroup with ﬁnite semilattice of idempotents in terms of that of the maximal group homomorphic image.
Title : Practise makes perfect : performance optimisation in ‘ arboreal ’ parkour 1 athletes illuminates the evolutionary ecology of great ape anatomy 2 3 Running title : Evolution of energetic ecology in great apes

24 An animal’s size is central to its ecology, yet remarkably little is known about the selective 25 pressures that drive this trait. A particularly compelling example is how ancestral apes 26 evolved large body mass in such a physically and energetically challenging environment as 27 the forest canopy, where weight-bearing branches and lianas are flexible, irregular and 28 discontinuous and the majority of preferred foods are situated on the most flexible branches 29 at the periphery of tree crowns. To date the issue has been intractable due to a lack of 30 relevant fossil material, the limited capacity of the fossil record to reconstruct an animal’s 31 behavioural-ecology and it not being possible to measure energy consumption in freely 32 moving apes. We studied the oxygen consumption of parkour athletes while traversing an 33 arboreal-like course as an elite model ape to test the ecomorphological and behavioural 34 mechanisms by which a large-bodied ape could optimize their energetic performance 35 during tree-based locomotion. Our results show that familiarity with the arboreal-like 36 course allowed the athletes to substantially reduce their energy expenditure. Furthermore, 37 athletes with larger arm-spans and shorter legs were particularly adept at finding energetic 38 savings. Our results flesh out the scanty fossil record to offer evidence that long, strong 39 arms, broad chests and a strong axial system, combined with the frequent use of uniform 40 branch-to-branch arboreal pathways, were critical to off-setting the mechanical and 41 energetic demands of large mass in ancestral apes. 42
Antioxidant Potential of Hesperidin Protects Gentamicin Induced Nephrotoxicity in Experimental Rats

Acute tubular necrosis is common with aminoglycoside therapy resulting in nephrotoxicity. The bioflavonoid, hesperidin is a specific flavonoid glycoside reported to act as a powerful antioxidant. Therefore, the present study investigates nephroprotective effect of hesperidin against gentamicin induced nephrotoxicity in rats. Thirty rats were randomly divided into five groups (n=6). Group I served as a control, Group II as a gentamicin control and was received vehicle for two days before and then treated with gentamicin (100 mg/kg/day) for eight days. Group III-V were received hesperidin orally at three doses (50, 100 and 200 mg/kg) two days before and eight days along with gentamicin (100 mg/kg/day). Hesperidin at doses of 100 and 200 mg/kg treatment significantly restored the body weight and kidney weight associated with the gentamicin. Moreover, significant changes in the biochemical parameters such as increased levels of BUN, serum creatinine and decreased urinary creatinine and creatinine clearance was observed in the hesperidin treated rats. Further increased MDA levels and decreased SOD and CAT activity as well as GSH levels were attenuated with hesperidin treatment (200 mg/kg). Necrosis and degenerative changes in glomeruli and tubules, observed in gentamicin treated rats were also been restored. Thus it suggests the antioxidant potential of hesperidin protect the gentamicin induced nephrotoxicity in rats. nitrogen; Antioxidant; Nephrotoxicity embryos from oxidative stress, and may regenerate beta cells of endocrine pancreas in experimental diabetes pregnancy [11]. and in in present to study the antioxidant potential of protects gentamicin
A Theoretical Approach to the Self Similarity Join in a Distributed Enviroment

—Efﬁcient processing of similarity joins is important for a large class of data analysis and data-mining applications. This primitive ﬁnds all pairs of records within a predeﬁned distance threshold of each other. However, most of the existing approaches have been based on spatial join techniques designed primarily for data in a vector space. Treating data collections as metric objects brings a great advantage in generality, because a single metric technique can be applied to many speciﬁc search problems quite different in nature. In this paper, we concentrate our attention on a special form of join, the Self Similarity Join , which retrieves pairs from the same dataset. In particular, we consider the case in which the dataset is split into subsets that are searched for self similarity join independently (e.g, in a distributed computing environment). To this end, we formalize the abstract concept of (cid:2) -Cover , prove its correctness, and demonstrate its effectiveness by applying it to two real implementations on a real-life large dataset.
Comparative Sequence Analysis of the Region Harboring the Hardness Locus in Barley and Its Colinear Region in Rice 1

The ancestral shared synteny concept has been advocated as an approach to positionally clone genes from complex genomes. However, the uniﬁed grass genome model and the study of grasses as a single syntenic genome is a topic of considerable controversy. Hence, more quantitative studies of cereal colinearity at the sequence level are required. This study compared a contiguous 300-kb sequence of the barley ( Hordeum vulgare ) genome with the colinear region in rice ( Oryza sativa ). The barley sequence harbors genes involved in endosperm texture, which may be the subject of distinctive evolutionary forces and is located at the extreme telomeric end of the short arm of chromosome 5H. Comparative sequence analysis revealed the presence of ﬁve orthologous genes and a complex, postspeciation evolutionary history involving small chromosomal rearrangements, a translocation, numerous gene duplications, and extensive transposon insertion. Discrepancies in gene content and microcolinearity indicate that caution should be exercised in the use of rice as a surrogate for map-based cloning of genes from large genome cereals such as barley. dbEST at the NCBI. Exon:intron splice junctions were determined bygenomic alignment with ESTs. Splice junctions wereconﬁrmed bythe presence of theconservedGTandAGintronbordersanda minimum of ﬁve of the nine (5 # -CAG:GTAAGT-3 # ) and three of the ﬁve (5 # -GCAG:G-3 # ) consensus nucleotides for the respective exon:intron and intron:exon splice sites in plants. Putative functions and conserved protein domains were determined using BLASTP analysis against the nrdb and swissprot database at NCBI. Identiﬁcation of colinear and homologous Arabidopsis and rice TAIR (http://www.arabidopsis.org/Blast/), Gramene using BLASTN, TBLASTN functions. Dotter program conserved regions between the BAC
The Economic Burden of Elevated Blood Glucose Levels in 2017: Diagnosed and Undiagnosed Diabetes, Gestational Diabetes, and Prediabetes

This study was conducted to update national estimates of the economic burden of undiagnosed diabetes, prediabetes, and gestational diabetes in the United States for year 2017 and provide state-level estimates. Combined with published estimates for diagnosed diabetes, these updated statistics provide a detailed picture of the economic costs associated with elevated blood glucose levels.
The Roles of Organic and NPK Compound Fertilizers for Four Year Old Mature Oil Palm ( Elaeis guineensis Jacq)

Oil palm becomes an important commodity as source of foreign exchange. Oil palm need a large of quantity of nutrients, thus fertilization is a key factor that must be considered to increase its growth and productivity. The objectives of this research were to study the role of organic and NPK compound fertilizers and its combination on growth and productivity for 4 year old of oil palm. The research was conducted at IPB-Cargill Teaching Farm of Oil Palm, Jonggol, Bogor West Java from March 2016 to March 2017. The experiment was carried out in a factorial randomized block design with three replications. The first factor was organic There was an interaction between manure and NPK compound fertilizer on leaf area, leaf N nutrient content and leaf P nutrient content. The best NPK compound fertilizer was 6 kg of plant -1 year -1 .
LINEAR REGULARITY FOR AN INFINITE SYSTEM FORMED BY p -UNIFORMLY SUBSMOOTH SETS IN BANACH SPACES

In this paper, we introduce and study p -uniform subsmoothness of a collection of infinitely many closed sets in a Banach space. Using variational analysis and techniques, we mainly study linear regularity for a collection of infinitely many closed sets satisfying p -uniform subsmoothness. The necessary or/and sufficient conditions on the linear regularity are obtained in this case. In particular, we extend the characterizations of linear regularity for a collection of infinitely many closed convex sets to the nonconvex setting.