Miracle-dz/UniFAR-FTUs huggingface dataset:
Prognostic Significance of Serum Interleukin-6 Levels in Oral Squamous Cell Carcinoma

Introduction The prognosis of oral squamous cell carcinoma (OSCC) is often poor despite standard treatments. Additionally, no useful prognostic markers are available. Therefore, we aimed to investigate the relationship between serum Interleukin-6 (IL-6) levels and prognosis and explore its local and systemic effects in patients with OSCC. Methods Ninety-five new cases of OSCC were included, and the prognosis was compared between high and low serum IL-6 groups. The localization of IL-6 in OSCC tissues was examined. Furthermore, a comprehensive gene expression analysis was performed in OSCC tissues and compared between the two groups. Results A significant difference in overall survival and disease-free survival was observed. Furthermore, a substantial expression of IL-6 was localized in the stroma. Comprehensive gene expression analysis of tumor localization showed increased expression of genes related to oxidoreductase and lipid metabolism in the primary tissues of the group with high serum IL-6 levels. Regarding the correlation between blood tests and serum IL-6 levels, a strong positive correlation was observed between inflammatory responses and nutritional factors. Conclusion These results suggest that serum IL-6 may be a prognostic factor for metabolic abnormalities in patients with OSCC and that aggressive nutritional interventions may contribute to prognosis.
Evidence of VLP volcanic tremor in the band [0.2–0.5] Hz at Stromboli volcano, Italy

We analyze time series of Strombolian volcanic tremor recorded with a network of broadband seismic stations. We evidence the occurrence of a significant component of volcanic tremor in the range [0.2–0.5] Hz by using linear and nonlinear methods. The polarization and ZLCC analysis show that the wave field is characterized by high apparent velocity (∼2 km/s). It comes mainly from the crater area with a clear amplitude decay towards the sea level. The previous properties are loosed when the tremor level is higher suggesting that in this case the wave field is more affected by oceanic noise. The waveform extracted by Independent Component Analysis (ICA) shows a behaviour like nonlinear “beats” as in the case of high frequency waveforms. We conclude that this component displays a behaviour like the wave field at higher frequencies in spite of its low frequency, and it is produced by the vibrations of the volcanic conduit.
Incidence of mental health conditions following pediatric hospital admissions: analysis of a national database

Introduction Despite increasing survival of children following hospitalization, hospitalization may increase iatrogenic risk for mental health (MH) disorders, including acute stress, post-traumatic stress, anxiety, or depression. Using a population-based retrospective cohort study, we assessed the rates of new MH diagnoses during the 12 months after hospitalization, including the moderating effects of ICU exposure. Study design/methods This was a retrospective case control study using the Truven Health Analytics insurance database. Inclusion criteria included children aged 3–21 years, insurance enrollment for >12 months before and after hospital admission. We excluded children with hospitalization 2 years prior to index hospitalization and those with prior MH diagnoses. We extracted admission type, ICD-10 codes, demographic, clinical, and service coordination variables from the database. We established age- and sex-matched cohorts of non-hospitalized children. The primary outcome was a new MH diagnosis. Multivariable regression methods examined the risk of incident MH disorder(s) between hospitalized and non-hospitalized children. Among hospitalized children, we further assessed effect modification from ICU (vs. non-ICU) stay, admission year, length of stay, medical complexity, and geographic region. Results New MH diagnoses occurred among 19,418 (7%) hospitalized children, 3,336 (8%) ICU-hospitalized children and 28,209 (5%) matched healthy controls. The most common MH diagnoses were anxiety (2.5%), depression (1.9%), and stress/trauma (2.2%) disorders. Hospitalization increased the odds of new MH diagnoses by 12.3% (OR: 1.123, 95% CI: 1.079–1.17) and ICU-hospitalization increased these odds by 63% (OR: 1.63, 95% CI: 1.483–1.79) as compared to matched, non-hospitalized children. Children with non-complex chronic diseases (OR: 2.91, 95% CI: 2.84–2.977) and complex chronic diseases (OR: 5.16, 95% CI: 5.032–5.289) had a substantially higher risk for new MH diagnoses after hospitalization compared to patients with acute illnesses. Conclusion Pediatric hospitalization is associated with higher, long-term risk of new mental health diagnoses, and ICU hospitalization further increases that risk within 12 months of the acute episode. Acute care hospitalization confers iatrogenic risks that warrant long-term mental and behavioral health follow-up.
Export Determinants of RCEP Negotiating Countries: Does REER Matter?

With the use of panel data analysis, this study seeks to determine how the Real Effective Exchange Rate (REER) affects the overall exports from the ASEAN-5 nations (Indonesia, Singapore, Malaysia, Thailand, and the Philippines) as well as several neighboring nations (Australia, India, Japan, South Korea, New Zealand, and China). An increase in a country's REER indicates a weakening of the country's trade competitiveness, assuming the other variables remain (ceteris paribus). Based on the results of the study, it was found that the effect of REER was different for ASEAN-5 and non-ASEAN and did not significantly affect the total exports of the 11 countries. The REER coefficient is positive for non-ASEAN countries and the value is higher for high-income countries. The REER coefficient is negative for ASEAN-5 countries but not significant. The negative value is more significant for middle-income countries. The effect of REER on total exports can depend on the type of commodity traded in a country (using natural resources that are abundant in the country or not). Export products that rely on imported raw materials cause when depreciation occurs, the price of raw materials becomes more expensive, increases the price of the final product, and also decreases the terms of trade of related products.Dengan menggunakan analisis data panel, penelitian ini bertujuan untuk mengetahui bagaimana Real Effective Exchange Rate (REER) mempengaruhi keseluruhan ekspor dari negara-negara ASEAN-5 (Indonesia, Singapura, Malaysia, Thailand, dan Filipina) serta beberapa negara tetangga (Australia, India, Jepang, Korea Selatan, Selandia Baru, dan Tiongkok). Peningkatan REER suatu negara mengindikasikan melemahnya daya saing perdagangan negara tersebut, dengan asumsi variabel lain tetap (ceteris paribus). Berdasarkan hasil penelitian diketahui bahwa pengaruh REER berbeda untuk ASEAN-5 dan non-ASEAN dan tidak berpengaruh signifikan terhadap total ekspor 11 negara tersebut. Koefisien REER positif untuk negara non-ASEAN dan nilainya lebih tinggi untuk negara berpenghasilan tinggi. Koefisien REER negatif untuk negara-negara ASEAN-5 tetapi tidak signifikan. Nilai negatifnya lebih besar dan signifikan untuk negara berpenghasilan menengah. Pengaruh REER terhadap total ekspor dapat bergantung pada jenis komoditas yang diperdagangkan di suatu negara (menggunakan sumber daya alam yang melimpah di negara tersebut atau tidak). Produksi barang ekspor dengan bahan baku impor menyebabkan ketika terjadi depresiasi, harga bahan baku menjadi lebih mahal, menaikkan harga produk akhir, sehingga menurunkan terms of trade produk terkait.
Pore Fluid Pressure Development in Compacting Fault Gouge in Theory, Experiments, and Nature

The strength of fault zones is strongly dependent on pore fluid pressures within them. Moreover, transient changes in pore fluid pressure can lead to a variety of slip behavior from creep to unstable slip manifested as earthquakes or slow slip events. The frictional properties of low‐permeability fault gouge in nature and experiment can be affected by pore fluid pressure development through compaction within the gouge layer, even when the boundaries are drained. Here the conditions under which significant pore fluid pressures develop are analyzed analytically, numerically, and experimentally. Friction experiments on low‐permeability fault gouge at different sliding velocities show progressive weakening as slip rate is increased, indicating that faster experiments are incapable of draining the pore fluid pressure produced by compaction. Experiments are used to constrain the evolution of the permeability and pore volume needed for numerical modeling of pore fluid pressure build up. The numerical results are in good agreement with the experiments, indicating that the principal physical processes have been considered. The model is used to analyze the effect of pore fluid pressure transients on the determination of the frictional properties, illustrating that intrinsic velocity‐strengthening behavior can appear velocity weakening if pore fluid pressure is not given sufficient time to equilibrate. The results illustrate that care must be taken when measuring experimentally the frictional characteristics of low‐permeability fault gouge. The contribution of compaction‐induced pore fluid pressurization leading to weakening of natural faults is considered. Cyclic pressurization of pore fluid within fault gouge during successive earthquakes on larger faults may reset porosity and hence the capacity for compaction weakening.
Differences between Health and Non-Health Science Students in Lifestyle Habits, Perceived Stress and Psychological Well-Being: A Cross-Sectional Study

The aim of this study was to investigate lifestyle habits in health and non-health science students from the University of Split, Croatia, and to evaluate their association with perceived stress and psychological well-being. We surveyed 783 students during February–March 2021. Hierarchical multiple regression analysis was used in the analysis. Health science students spent less time using screens, were sitting less, slept less, but also showed better compliance with the Mediterranean diet compared to non-health science students (10.6% vs. 5.9%). There were no differences in stress and well-being perception between the two study groups. Female gender, lack of sleep, less daily sitting time, anxiety, and lower optimism were associated with higher stress in non-health science students, while anxiousness and more sitting were found to be significant among health students. Well-being among health science students was positively associated with BMI, having had COVID-19, being refreshed after waking up during working days, Mediterranean diet adherence, health perception, optimism, and quality of life, and negatively with TV time and anxiousness. Shorter sleep duration on non-working days, feeling refreshed after waking up on non-working days, higher quality of life and optimism, and lower anxiousness were associated with higher well-being among non-health students. Identifying unhealthy lifestyle habits in students is essential for implementing targeted interventions to better their health outcomes.
Growth, Productivity and Quality Performance of Costata Persimmon in Relation to Canopy Position and Rootstock

According to their position within a tree canopy, fruits will be exposed to varied climatic conditions especially light and temperature, which would reflect variation in their growth and maturation. In the present study, the differences occurring in vegetative growth, fruit yield and quality of Costata persimmon in accordance with rootstock type and fruit position in the canopy were investigated. Periphery especially, both southern and western directions besides the upper part and the outer canopy side indicated the highest values of fruit retention, average fruit number per shoot, fruit yield, spring shoot length, leaf area, total leaf area per fruit and leaf chlorophyll content. While the percentage of sunburned fruits was lower at both northern and eastern directions, as well as at the lower and inner part than the other directions of tree canopy. The best fruit physiochemical characteristics were found in both western and southern directions, as well as the upper part and outer part of the tree canopy. Trees grown on seedy rootstock gave the highest values of fruit yield, shoot length, leaf area and total leaf area per fruit. Along with lower sunburned fruits, longer, wider, heavier and firmer fruits were also found on Seedy rootstock.
Variability of the Space‐Time Evolution of Slow Slip Events Off the Boso Peninsula, Central Japan, From 1996 to 2014

Global Navigation Satellite System data are inverted to investigate the space‐time evolution of five Mw 6.6–6.7 slow slip events (SSEs) off the Boso Peninsula, central Japan, in 1996, 2002, 2007, 2011, and 2013–2014. Our analyses reveal that the nucleation style and space‐time evolution of slip vary among the five SSEs. The 2002, 2007, and 2011 SSEs nucleated more rapidly, with moment accelerations higher than those of the 1996 SSE by a factor of ∼2–6, and higher than those of the 2013–2014 SSE by an order of magnitude. Furthermore, the 2002, 2007, and 2011 SSEs exhibited more rapid temporal variations in their slip and moment rates and showed larger seismic moments and higher maximum slip rates than the 1996 and 2013–2014 SSEs, suggesting that the overall evolution of the SSEs is correlated with the nucleation style. The along‐strike expansion/propagation of slip is identified for the five SSEs, revealing that the expansion/propagation patterns vary from event to event. The earthquake swarms accompanying the SSEs occurred near the downdip edge of high‐slip‐rate areas, and the seismicity migrated during slow slip with directions and speeds similar to those of the slip expansion/propagation. These space‐time correlations between seismicity and slow slip suggest that the earthquake swarms were triggered by stress changes due to slow slip. The relative timing between the onsets of the SSEs and their associated seismicity varies from event to event and appears to be correlated with the nucleation style of the SSEs.
Survey of Emotional Themes Used in Marketing of Commercial Baby Foods in the UK—Implications for Nutrition Promotion in Early Childhood

Claims used in the marketing of commercial baby foods are often misleading, and there are concerns that they exploit parental anxieties. We adapted a hierarchical consumer emotions model to explore the emotional themes used in the marketing of commercial baby foods sold in the UK market. A survey administered in three large UK supermarkets collected in-store data on commercial baby food characteristics and the marketing claims used on commercial baby food packaging. The keywords found in these claims were entered in N-Vivo and allocated to four preexisting emotional themes: contentment, happiness, love, and pride. The prevalence of each theme was compared by age suitability (4+, 6+, 9+, and 12+ months) and taste (sweet/savoury) profile. A total of 1666 marketing claims (median 5, IQR 3) and 1003 emotional keywords (median 3, IQR 3) were identified on the packaging of 341 commercial baby foods. Foods suitable for infants aged 6+ months displayed more claims (50%, p < 0.05) and emotional keywords (56%, p = 0.07). Savoury foods displayed more emotional keywords (63%, p < 0.001). The keywords “little”, “encourage”, “love(ly)”, and “tiny” were the most frequently used words under the theme of love (36% total contribution). The emotional connotations of the keywords under the theme “love” are extensively used in the marketing claims on commercial baby food packaging. These might exploit parental vulnerabilities and influence their purchasing of commercial baby foods.
Venonia amygdalina leaf extract - mediated redox synthesis of silver nanoparticles: Characterization and antimicrobial activity

The synthetic process, type of precursor material, and the phytochemical materials involved in the biological synthesis of metal nanoparticles influence the properties of the resulting nanoparticles. The physicochemical attributes of synthesized nanoparticles, in turn, influence their applicability for various purposes, hence the need to standardize synthetic processes and characterize nanoparticle outputs for reproducibility and optimal utility. The objective of this study was to utilize bitter leaf ( Vernonia amygdalina ) extract in the synthesis of silver nanoparticles (AgNPs), characterize the nanoparticles
Development of a Green, Quick, and Efficient Method Based on Ultrasound-Assisted Extraction Followed by HPLC-DAD for the Analysis of Bioactive Glycoalkaloids in Potato Peel Waste

α-Solanine and α-chaconine are the two most predominant glycoalkaloids (GAs) present in potato. Potato peel contains a high concentration of GAs, which are especially interesting for application in the pharmaceutical industry due to their different beneficial properties (such as anticarcinogenic, anti-inflammatory, antiallergic, antipyretic, antiviral, fungicide, and antibiotic activities, among others); so, potato peel waste can be valorized by extracting these biologically active compounds. For this, a green, quick, and efficient miniaturized analytical approach based on ultrasound-assisted extraction (UAE) combined with HPLC-DAD was developed to quantify α-solanine and α-chaconine in potato peel. Some parameters of the extraction were optimized, including the extraction method, the type of solvent, and the sample/solvent ratio, by a three-factor, three-level (33) full factorial experimental design. The optimal extraction conditions were obtained with UAE using methanol as a solvent and a sample/solvent ratio of 1:10 (w/v, g/mL). The analytical greenness metric for sample preparation (AGREEprep) tool was used to assess the greenness of the methods used. The tool revealed an acceptable green analysis, with 0.61 points. The method was validated and applied to the evaluation of GAs in the peel of 15 commercial varieties of potato. The amount of glycoalkaloids found in the samples evaluated ranged from 143 to 1273 mg/kg and from 117 to 1742 mg/kg dry weight for α-solanine and α-chaconine, respectively. These results reveal the important variability that exists between potato varieties; so, their analysis is of great importance to select the most suitable ones for biovalorization (e.g., the Amandine and Rudolph varieties, with around 3000 mg/kg, in total, of both GAs). To provide higher stability to the peel during storage, freeze-drying or a medium-temperature drying process resulted preferable to avoid GA degradation. Overall, this study will contribute to the expansion of the future biovalorization of potato peel waste as well as provide a powerful analytical tool for GA analysis.
Adaptation and forage yield of Vetches (Vicia spp.) in the southern highlands of Ethiopia

The Southern Nations and Nationalities and Peoples region (SNNPR) of Ethiopia has diversi ed animal feed resources, livestock species and suitable agro ecology for crop livestock production. In the region there are different kinds of feed resources for use as animal feed. The feeds that are mainly used as animal feeds are crop residues, natural/green pastures and feeds from grazing lands. However, the fodder from grazing lands is poor in quantity and quality due to overgrazing and overstocking. Crop residues are also of poor quality unless otherwise supplemented with other feeds which are rich in protein such as legumes [1].
Factors of BPD Deposit Interest Rate, Government Bank Deposit Interest Rate, Inflation Rate, Economic Growth (GDP) and Money Supply to the Rupiah Exchange Rate per US dollar in Indonesia for the Period 2004 - 2021

The study aims to analyze the effect of the BPD Deposit Interest Rate Factor, Government Bank Deposit Interest Rate, Inflation Rate, economic growth, and money supply affecting the exchange rate of the rupiah per US dollar in 2004-2021 partially and simultaneously. The research method uses secondary data in the form of panel data and cross section for 18 years (quarterly data on 26 provinces in Indonesia). Literature survey research from BI, BPD, and BPS Center. Quantitative analysis method using multiple linear regression analysis tools. The results showed that (1) partially, the interest rate factor of Government Bank deposits, the money supply has a positive but insignificant effect on the exchange rate of the rupiah per US dollar. Regional Development Bank deposit interest rates, inflation rates, and economic growth have a negative but significant effect on the exchange rate of the rupiah per US dollar; and (2) simultaneously, the factors of interest rates on deposits of BPD, interest rates on deposits of Government Banks, inflation rates, economic growth, money supply have a significant effect on the exchange rate of rupiah per US dollar. An increase in interest rates on deposits of Government Banks and money supply, a decrease in interest rates on deposits of BPD, inflation rates, and economic growth will increase the exchange rate of rupiah (depreciated).
Survival outcomes correlate with the level of cell-free circulating DNA in ST-elevation myocardial infarction

Background: Myocardial infarction (MI) can lead to higher cellular damage, making cell-free DNA (cfDNA) a potential biomarker for assessing disease severity. The aim of this study is to evaluate survival predictions using cfDNA measurements and assess its correlation with MI. Materials and Methods: A direct fluorescence assay was employed to measure cfDNA content in the blood samples of participants. The inclusion criteria included patients who gave informed consent, suffering from ST-elevation myocardial infraction (STEMI) based on established diagnostic criteria (joint ESC/ACC guidelines), between the age of 18 and 80 years old, and had elevated troponin biomarker levels. The study included 150 patients diagnosed with STEMI and 50 healthy volunteers as controls. Serial monitoring of patients was conducted to track their postdisease status. The rate of change of cfDNA was calculated and daily measurements for 7 days were recorded. Results: Mean levels of cfDNA were found to be 5.93 times higher in patients with STEMI compared to healthy controls, providing clear evidence of a clinical correlation between cfDNA and STEMI. Patients were further categorized based on their survival status within a 90-day period. The study observed a strong predictive relationship between the rate of change of cfDNA during daily measurements and survival outcomes. To assess its predictive capability, a receiver operating characteristics (ROC) curve analysis was performed. The ROC analysis identified an optimal cutoff value of 2.50 for cfDNA, with a sensitivity of 81.5% and specificity of 74.0% in predicting disease outcomes. Conclusion: This study demonstrates a robust association between cfDNA and STEMI, indicating that cfDNA levels can be a valuable early prognostic factor for patients. Serial measurements of cfDNA during early disease onset hold promise as an effective approach for predicting survival outcomes in MI patients.
The geography of development in Latin America and the Caribbean: Towards a new multidimensional taxonomy of the Sustainable Development Goals

The Latin America and the Caribbean region has an ambiguous place in the new geography of development: while it is a predominantly middle-income region, it is home to no more than 3% of the world’s poor population. Consequently, there is a risk that the international community will (mis)interpret this situation as meaning that the region need not be prioritized in the 2030 Agenda for Sustainable Development. Nonetheless, the Sustainable Development Goals are not merely a strategy to combat economic poverty, but also a multidimensional strategy that defines a complex world map of priorities. This article develops a multidimensional taxonomy that addresses the fundamental dimensions of sustainable human development, beyond classifications based exclusively on per capita income. Cluster analysis is used to identify the different challenges faced by Latin American and Caribbean countries and to provide guidance for international cooperation policies.