Miracle-dz/UniFAR-FTUs huggingface dataset:
A qualitative exploration of fatherhood after acquired brain injury (ABI)

ABSTRACT Acquired Brain Injury (ABI) significantly affects individuals across multiple areas of intimate, familial, and parental domains. Gender and identity are pivotal research areas in navigating life after ABI. To date, scant research has explored gendered experiences, particularly those related to the masculine lifeworld. This study aimed to explore how men who were fathers before their injuries experience fatherhood after ABI. An Interpretative phenomenological analysis (IPA) methodology was used, and seven fathers participated in the semi-structured interviews (time since injury 1-18 years, age range 27-66 years) which explored their meaning-making. Four superordinate themes were drawn from all interviews through engaging with the qualitative research process: (1) what being a father means, (2) altered relationships with others, (3) becoming lost and finding their way through, and (4) renewed fatherhood. The findings show intersectionality between pre-and post-injury comparisons of self and social identities, alongside the contextual and societal identities in the subjective fathering experiences. Through increased understanding, we may enable fathers to find new ways to resolve, reformulate, and connect to move into their future possible fatherhood. The importance of this research is in giving voice to these less represented men so that we may shape our understanding to aid future fathers post-ABI.
Propylene glycol: a promising preservative for insects, comparable to ethanol, from trapping to DNA analysis

Recent advances in DNA analysis allow us to identify an unprecedented number of insect samples collected by mass sampling techniques such as insect traps. In these circumstances, a preservative that can be applied from trap to storage is necessary to prevent degradation of DNA before analysis and save on the cost of labor for collecting insects from traps. Propylene glycol has a prominent feature as a trap solution. We aimed to examine the DNA preservability of 98% propylene glycol at 2 weeks and more than 6 months after initial collection in comparison with 99.5% ethanol, which is commonly used for storage of specimens for genetic analysis. We compared amplification performance of PCR targeting a specific region of the mitochondrial cytochrome c oxidase subunit I (COI) gene in the orders Hymenoptera, Diptera, and Coleoptera using two extraction methods varying in extraction efficiency. Even after 6 months, more than 75% of samples were recognized to have succeeded in PCR amplification irrespective of preservatives by the extraction method with higher extraction efficiency. It suggested that mitochondrial DNA was preserved in both solutions. However, dim bands in the electrophoreses of PCR products increased with time in extracts by another method with lower extraction efficiency. In Diptera and Coleoptera, the rate of dim bands increased more rapidly for ethanol‐preserved than for propylene glycol‐preserved specimens, indicating higher DNA preservability of propylene glycol over time for these taxa. On the other hand, in Hymenoptera, the preservatives did not affect PCR amplification performance. Considering its safer characteristics and high DNA preservability in a wide range of taxa, propylene glycol can be a promising solution from trapping of insects to storage for genetic analysis.
Investing in the intellectual potential of society: the example of Kazakhstan

Intellectual capital is the most important component of the production assets of the organization operating in the post-industrial information society. The intellectual potential of the society is determined by the following main factors: the quality of the state socio-economic policy; the genetic fund of the population; the quality of the living environment (the level and quality of life of the population, ecology, political climate, etc.) of the population in general and its individual groups in particular; the level of health of the population; the level of development of the system of education and training of the younger generation; the quality of the mechanism of motivation of the population to creative work; the structure of society and the employed population; the level of culture and national consciousness of the population. Investments in intellectual potential play a major role in its development. This article analyzes the main factors affecting the development of the intellectual potential of society since the collapse of the Soviet Union. The main purpose of the study is to analyze and study the main factors affecting the growth of investment in the intellectual capital of the society. Research methodology includes such methods of study of economic phenomena and processes: economic and statistical analysis. The results of the study will allow to study the successful experience, as well as to identify problem areas in the financing of the intellectual potential of society. The scientific and practical significance of the work lies in the fact that its main conclusions and recommendations can be used to develop effective strategies and tactical instruments of innovation policy.
Breaking news of disasters: How Stuff.co.nz and NZHerald.co.nz used Facebook and Twitter in the 2016 Kaikoura earthquake coverage in New Zealand

Abstract This study looks at how media users reacted and engaged with Facebook and Twitter posts of two major New Zealand news websites—Stuff.co.nz and NZHerald.co.nz—during the coverage of the 7.8 magnitude Kaikoura earthquake in November 2016. Using posts (n = 975) on Facebook pages and tweets (n = 889) on Twitter handles of Stuff.co.nz and NZHerald.co.nz from 12 November to 17 November, we analysed how media users reacted to breaking news coverage of a major natural disaster. The results show that quake news gets significantly more interaction and reactions than non-quake news on both social media platforms. For Twitter, quake news gets significantly more interactions such as likes, and retweets, but not replies. However, for Facebook, quake news gets significantly more comments, likes, wows, and sad emotional feedbacks, but no significant difference in emotions such as love, haha, and angry. The emotions people have on Facebook indicate well the nature of the news. With Facebook’s new function of reactions including, like, love, haha, wow, sad, angry, makes reactions more expressive and relevant. The study also shows a clear pattern of reactions on the two social media platforms across the timeline. While the number of posts keeps stable over the period, users’ reactions soared in the first two days of the quake; The responses subsided after the chaotic period of the disaster was over. The study provides an insight into how mainstream news websites are using social media in reporting and engaging with users during major natural disasters. Limitations of the study and suggestions for future research are also discussed.
Evaluation of modified Alvarado scoring system and RIPASA scoring system as diagnostic tools of acute appendicitis

Background: Acute appendicitis is the most common surgical condition presented in emergency departments worldwide. Clinical scoring systems, such as the Alvarado and modified Alvarado scoring systems, were developed with the goal of reducing the negative appendectomy rate to 5%–10%. The Raja Isteri Pengiran Anak Saleha Appendicitis (RIPASA) scoring system was established in 2008 specifically for Asian populations. The aim of this study was to compare the modified Alvarado with the RIPASA scoring system in Kuwait population. Methods: This study included 90 patients who underwent appendectomies and were documented as having “acute appendicitis” or “abdominal pain” in the operating theatre register from June 2014 to May 2018. The sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), diagnostic accuracy, predicted negative appendectomy and receiver operating characteristic (ROC) curve of the modified Alvarado and RIPASA scoring systems were derived using SPSS statistical software. Results: A total of 68 patients were included in this study according to our criteria. The cut-off threshold point of the modified Alvarado score was set at 7.0, which yielded a sensitivity of 82.8% and a specificity of 56%. The PPV was 89.3% and the NPV was 42.4%. The cut-off threshold point of the RIPASA score was set at 7.5, which yielded a 94.5% sensitivity and an 88% specificity. The PPV was 97.2% and the NPV was 78.5%. The predicted negative appendectomy rates were 10.7% and 2.2% for the modified Alvarado and RIPASA scoring systems, respectively. The negative appendectomy rate decreased significantly, from 18.4% to 10.7% for the modified Alvarado, and to 2.2% for the RIPASA scoring system, which was a significant difference (P<0.001) for both scoring systems. Conclusion: Based on the results of this study, the RIPASA score is a simple scoring system with better sensitivity and specificity than the modified Alvarado scoring system in Asian populations. It consists of 14 clinical parameters that can be obtained from a good patient history, clinical examination and laboratory investigations. The RIPASA scoring system is more accurate and specific than the modified Alvarado scoring system for Kuwait population.
Qualidade de sono em estudantes de medicina: comparação das diferentes fases do curso

OBJECTIVE To evaluate and compare subjective sleep quality in medical students across the various phases of the medical course. METHODS This was a cross-sectional study involving medical undergraduates at one medical school in the city of Botucatu, Brazil. All first- to sixth-year students were invited to complete the Pittsburgh Sleep Quality Index, which has been validated for use in Brazil. Participants were divided into three groups according to the phase of the medical course: group A (first- and second-years); group B (third- and fourth-years); and group C (fifth- and sixth-years). The results obtained for the instrument components were analyzed for the total sample and for the groups. RESULTS Of the 540 students invited to participate, 372 completed the instrument fully. Of those, 147 (39.5%) reported their sleep quality to be either very or fairly bad; 110 (29.5%) reported taking more than 30 min to fall asleep; 253 (68.0%) reported sleeping 6-7 h per night; 327 (87.9%) reported adequate sleep efficiency; 315 (84.6%) reported no sleep disturbances; 32 (8.6%) reported using sleeping medication; and 137 (36.9%) reported difficulty staying awake during the day at least once a week. Group comparison revealed that students in group A had worse subjective sleep quality and greater daytime dysfunction than did those in groups B and C. CONCLUSIONS Medical students seem to be more exposed to sleep disturbance than other university students, and first- and second-years are more affected than those in other class years because they have worse subjective sleep quality. Active interventions should be implemented to improve sleep hygiene in medical students.
Challenges in smoking cessation for people with chronic obstructive pulmonary disease

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Significance of Silver Stained Nucleolar Organiser Region (AgNOR) in Fine Needle Aspiration Smears of Breast Lesions

Background: Breast cancer is the leading cause of cancer - related deaths in Asia. The number of intra-nuclear silver stained structures, termed AgNORs, is significantly higher in malignant cells than in normal, reactive or benign cells. The purpose of this study was to evaluate the AgNOR scores in FNA smears of breast lesions and their correlation with histopathology. Aims & Objective: To establish AgNOR staining as a diagnostic and prognostic tool in management of various breast lesions. Methods: This was a prospective study conducted over a period of 18 months may 2015 to November 2016. A total of 100 cases were included in the study. AgNOR stain was done in both cytology and scoring was done and analysed. Results: In FNAC aspirates, Mean AgNOR count ranged from 5 to 9.9 per high power field with a mean value of 2.888±2.553. The AgNOR dots morphology was homogenous, symmetric with regular contours in FNAC slides of benign breast lesion. In malignant breast lesions, the dots were asymmetric with irregular contours and were aggregated, smaller and more scattered. Conclusions: The present study showed that fine needle aspiration cytology is a useful modality for diagnosis of breast lesions. It has a high concordance with the histopathology . AgNOR count assessment provides a useful objective measure for segregation of different grades of tumor with 100% accuracy for detection of higher grade of lesions, as observed in present study. For differentiation of benign from malignant lesions too it has a high sensitivity as well as specificity. The usefulness of FNAC to evaluate nodal involvement also showed a 90% sensitivity and 95.6% specificity. On the basis of present study, it could be concluded that AgNOR count estimation using fine needle aspiration is a useful method to differentiate and diagnose breast lesions.
Preventive effects of hesperidin on diabetic nephropathy induced by streptozotocin via modulating TGF-β1 and oxidative DNA damage

Abstract Hesperidin (HSP) is a natural bioflavonoid with active pharmacological properties. This study was conducted to investigate the hypoglycemic and antioxidant effects of HSP on streptozotocin-induced diabetic nephropathy in rats. Serum urea, creatinine and malondialdehyde levels increased in the diabetic group, while antioxidant enzyme activities decreased compared to the control group. Moreover, transforming growth factor-beta 1 level, 8-hydroxy-2′-deoxyguanosine expression and histopathological changes in renal tissue were increased in the diabetic group. On the other hand, HSP therapy significantly regulated these values in diabetic rats. Our results indicated that HSP might be helpful to protect diabetic nephropathy.
Eudragit S100 Entrapped Liposome for Curcumin Delivery: Anti-Oxidative Effect in Caco-2 Cells

Curcumin is a natural polyphenol with strong antioxidant activity. However, this molecule shows a very poor bioavailability, instability, and rapid metabolism in vivo. In this work curcumin was loaded in Eudragit-coated liposomes to create a gastroresistant carrier, able to protect its load from degradation and free it at the site of absorption in the colon region. Small unilamellar vesicles were prepared and coated with Eudragit by a pH-driven method. The physico-chemical properties of the prepared systems were assessed by light scattering, transmission electron microscopy, infrared spectroscopy, and differential scanning calorimetry. The uptake of vesicles by Caco-2 cells and the anti-oxidant activity in cells were evaluated. The produced vesicles showed dimensions of about forty nanometers that after covering with Eudragit resulted to have micrometric dimensions at acid pH. The experiments showed that at pH > 7.0 the polymeric coating dissolves, releasing the nanometric liposomes and allowing them to enter Caco-2 cells. Delivered curcumin loaded vesicles were then able to decrease significantly ROS levels as induced by H2O2 in Caco-2 cells. The proposed work showed the possibility of realizing effective gastroresistant curcumin liposome formulations for the delivery of antioxidant molecules to Caco-2 cells, potentially applicable to the treatment of pathological conditions related to intestinal oxidative stress.
Voting Behavior and Economics - An Analysis of Individual and Municipal Voting Behavior in Sweden

This study aims to determine if there is a relationship between a few chosen socio-economic and economic factors and the results of the 2006 and 2010 Swedish elections. The thesis relates to both individualand municipal levels. By using logistic and OLS regressions, for our individual and municipal data, respectively, we found links between some of our chosen factors and the election results. We see clear differences between our four regressions, which shows clear distinctions between the Moderate and the Social Democratic Party. The thesis found a positive effect of a higher degree of financial assistance in a municipality on the vote for the Social Democratic Party. Similarly, the same variable was negative for the Moderate Party. The same contrary relationship occurs for higher education level, where the variable is positive for the Moderate Party and negative for the Social Democratic Party. Concluding our thesis, we discuss how individual socio-economic factors may not be as important, and contemplate whether individual data are less relevant than collecting broader municipal data, with the aim of finding the effects of socio-economic and economic factors on a vote. Bachelor’s thesis in Economics, 15 credits Fall 2019 Supervisor: Elina Lampi Department of Economics School of Business, Economics and Law University of Gothenburg
Metabolic Syndrome Associated with Subclinical Hypothyroidism and Vit D Insufficiency - A Case Report and Discussion

Metabolic syndrome (MetS) associated with hypothyroidism, was reported in literature. Like-wise association between hypothyroidism and Vit. D deficiency was reported. Hypothyroidism, Vit. D deficiency in DM2 patients was also reported, in the literature. But the occurrence of MetS, hypothyroidism and Vit. D deficiency, together occurring in a case was unreported. The author presented such triple association in a male patient aged 54 years. While Met S itself was a risk factor for CVD (cardiovascular vascular disease) and so were independently, the hypothyroidism and hypovitaminosis D, the triple association would have cumulative risk for CVD. So, it would be profitable to screen all MetS cases with hypothyroidism, for Vit. D deficiency also, in view of the possible cumulative risk. Literature was reviewed as to the relationship of MetS to hypothyroidism and Vit D deficiency, as well as the changing diagnostic criteria of MetS and it’s pathogenesis.
Isolation and Characterization of Endophytic Bacteria from Nodule, Root and Seeds of Greengram (Vigna radiata L.)

Plants are host to one or more endophytic microorganisms. However the endophyte plant interaction is one of the least studied biochemical system in nature. The present experiment was conducted to isolate endophytic bacteria from surface sterilized nodules, roots and seeds of Greengram. Total 10 endophytic bacteria were obtained from nodules, roots and seeds of Greengram. Highest population of endophytic bacteria were observed in nodules (7.5 ×10 5 CFU/g) followed by root (5.6×10 5 CFU/g) and seeds (3.2×10 5 CFU/g). Based on microscopic observation it was found that all the 10 isolates were rod shaped, when studied for gram reaction out of 10 isolates 8 isolates showed negative reaction, out of ten 6 isolates were motile and remaining 4 isolates were non motile and with regards to endospore formation test 4 isolates were observed as endospore forming bacteria and remaining 6 isolates were non endospore formers. With respect to biochemical characterization all isolates showed positive results for catalase test, citrate utilization, phosphate solubilization and casein production tests and all isolates showed negative result for Indole production and Voges-Proskauer test.
Determinants and Prognostic Value of Longitudinal Strain in Asymptomatic Aortic Stenosis and Preserved Left Ventricular Ejection Fraction—The COFRASA/GENERAC Study

ABSTRACT Background: Longitudinal strain has been proposed as a sensitive marker of left ventricular systolic dysfunction. However its prognostic value in patients with aortic stenosis (AS) remains debated. Methods: In a prospective cohort of asymptomatic patients with at least mild, isolated AS and preserved left ventricular ejection fraction (LVEF), clinical, biological measurements, global longitudinal strain (GLS) and basal longitudinal strain (BLS) were performed at study entry. The occurrence of AS-related events (sudden death, congestive heart failure, new onset of symptoms) or aortic valve replacement within two years was recorded prospectively. Results: A total of 140 patients were enrolled and 21 events occurred. In contrast to GLS, BLS was significantly correlated to AS severity (p = 0.0006 with PV, p = 0.0002 with MPG, p = 0.01 with AVA, and p = 0.0009 with AVAi) and predicted the occurrence of AS-related events in the subset of severe AS in univariate analysis (p = 0.03) and after adjustment for AVA (p = 0.01), AVAi (p = 0.01), PV (p = 0.045), and MPG (p = 0.05). However, there was an important overlap of baseline BLS values between patients who developed symptoms and those who did not and repeated BLS measurements showed no difference between baseline values and those obtained at the time of overt symptoms in nine patients (p = 0.38). Conclusion: BLS was statistically predictive of AS-related events in the subset of severe AS. However, overlap of BLS values between groups of symptomatic status and similar values at baseline and at the time of overt symptoms raise the question of its use at an individual level at least as a single isolated parameter.
Biometrical characteristics of Cina hanh ducks of Assam

Biometrical characteristics of Cina hanh ducks of Assam were investigated. The data were collected from 110 male and 250 female at 30 weeks of age from the breeding tract of Cina hanh found in certain districts of Assam. The mean measurements of different body parts of Cina hanh revealed significantly (P
Horse-related trauma: A one-year Incidence study

Introduction Horse-related injuries have historically been described as both common and sometimes severe, often in young people. The main goals in this study were to describe the incidence and nature of horse related accidents in the county of Ostergotland as well as provide data on health care consumption and usage of safety equipment. Furthermore, current results were compared with our previous study that examined horse-related trauma in Ostergotland, Sweden between 2003 and 2004. Patients and Methods The nursing staff recruited patients presenting with horse related trauma at the Emergency Department at the University Hospital of Linkoping from March 2012 until March 2013. A questionnaire was sent to the study participants and the medical records of the respondents were reviewed. Results In total, there were 144 patients asked to participate in this study, 103 patients responded to the questionnaire. The patients were divided in two groups according to age, one group under the age of 19 years (Children) and one group 19 years of age and above (Adults). The total incidence of horse related accidents was 1, 2 accidents per 1000h spent with horses. The children had 4, 0 accidents per 1000h of horse riding and 3, 5 non-riding accidents per 1000h of horse care. The adults suffered 2, 9 accidents per 1000h of horse riding and 1, 1 non-riding accident per 1000h of horse care. In total, 14 patients, all adults, sustained severe injuries. Children were significantly more likely to own a safety vest and to use safety vest and riding boots at the time of the accident. For helmet and safety stirrups, no difference between children and adults was observed. Conclusion Severe injuries have increased in our population between the study periods. Among the children, we saw no severe injuries or death which may be due to increased use of safety equipment and/or change of riding behavior. The adults had more days of sick leave than in the previous study. Future preventive measures should focus on extremity injuries.