Miracle-dz/UniFAR-FTUs huggingface dataset:
Functional Endoscopic Sinus Surgery Comparison in a Tertiary Care Hospital

Two of the commonest indications for FESS are chronic rhinosinusitis without polyps and chronic rhinosinusitis with ethmoid polyps. This prospective study was carried out in Manipal Teaching Hospital, Pokhara to compare the results of FESS for bilateral chronic rhinosinusitis with and without ethmoid polyps. The study comprised of a cohort of 104 patients with bilateral chronic rhinosinusitis who underwent FESS between January 2012 and December 2014. The patients were divided into group 1 (without ethmoid polyps) and group 2 (with ethmoid polyps). Results in the two groups were assessed by comparing the Lund-Kennedy nasal endoscopic grading scores and Sino Nasal Outcome Test (SNOT-22) scores. Statistical analysis was done with Statistical Package for Social Sciences (SPSS) version 16.0. Statistical significance was set at p<0.05. The Lund-Mackay CT scan mean scores for group 1 and group 2 were 14.02 and 15.28 respectively before surgery (p = 0.11). Lund-Kennedy endoscopic score 3 months after FESS were much better in group 2 patients than in group 1(p<0.00001). After FESS, there was significant improvement in SNOT-22 scores in both groups. The SNOT-22 scores 3 months after FESS were much better in patients of group 2 than in patients of group 1(p<0.0001). The improvement in post-operative endoscopic grading and SNOT-22 scores wasmore in patients of chronic rhinosinusitis with ethmoid polyps than in patients without ethmoid polyps. There was no improvement in decreased sense of smell after FESS in most patients with ethmoid polyps.
Maternal Exposure to Ambient Air Pollution and Risk of Preeclampsia: A Population-Based Cohort Study in Scania, Sweden

The aim of this study was to investigate the risk of developing preeclampsia (PE) associated with gestational exposure to ambient air pollutants in southern Sweden, a low-exposure area. We used a cohort of 43,688 singleton pregnancies and monthly mean exposure levels of black carbon (BC), local and total particulate matter (PM2.5 and PM10), and NOX at the maternal residential address estimated by Gaussian dispersion modeling from 2000 to 2009. Analyses were conducted using binary logistic regression. A subtype analysis for small-for-gestational age (SGA) was performed. All analyses were adjusted for obstetrical risk factors and socioeconomic predictors. There were 1286 (2.9%) PE cases in the analysis. An adjusted odds ratio (AOR) of 1.35 with a 95% confidence interval (CI) of 1.11–1.63 was found when comparing the lowest quartile of BC exposure to the highest quartile in the third trimester The AOR for PE associated with each 5 µg/m3 increase in locally emitted PM2.5 was 2.74 (95% CI: 1.68, 4.47) in the entire pregnancy. Similar patterns were observed for each 5 µg/m3 increment in locally emitted PM10. In pregnancies complicated by PE with SGA, the corresponding AOR for linear increases in BC was 3.48 (95% CI: 1.67, 7.27). In this low-level setting, maternal exposure to ambient air pollution during gestation was associated with the risk of developing PE. The associations seemed more pronounced in pregnancies with SGA complications, a finding that should be investigated further.
Conhecimento de portadores de diabetes mellitus acerca da conservação da insulina

O objetivo deste estudo foi avaliar o conhecimento dos portadores de diabetes mellitus (DM) sobre a conservação da insulina. A pesquisa foi direcionada a 244 usuários de insulina, abordados em redes sociais voltadas para a DM, que responderam no primeiro semestre de 2018, questionário acerca da conservação da insulina. Os resultados mostraram que em relação à caneta reutilizável em uso, 80,7% guardam fora da geladeira, destes 46% a deixam fora do estojo original. O armazenamento dos frascos de insulina em uso dentro da geladeira é realizado por 84,8% da amostra, utilizando para a conservação as prateleiras (36%), porta (36,8%) e gaveta de legumes (12%). Já os frascos de insulina lacrados, nas prateleiras (47,8%), na porta (30,1 %), na gaveta de legumes (21,3%). O uso de recipiente térmico para transporte é usado por 77,7% ao ir para trabalho/escola, 84,1% para praia/piscina e 62,9% para ir da farmácia para casa. Constatou-se que o armazenamento de canetas e frascos de insulina, assim como seu transporte, ocorre de maneira inadequada em uma parcela da amostra. Através desse resultado, que evidencia um diagnóstico do conhecimento de usuários de insulina, é possível que os profissionais de saúde atualizem suas práticas de educação em saúde tornando-as mais efetivas para essa população.
The Effects of Different Implant and Feed Additive Strategies on Performance and Carcass Characteristics in Finishing Heifers: A Review

Data from 14 trials were pooled to determine the effects of nine different implant strategies for finishing heifers. The nine implant strategies involved single implant programs and reimplant programs with estrogen and androgen combinations. Feed intake, average daily gain, feed to gain, days on feed, dressing percentage, fat thickness, percentage choice, and percentage yield grades 4 and 5 were analyzed for the nine implant strategies for heifers. Average daily gains were significantly (P < .05) improved with reimplantation and as higher levels of estrogen and androgen was incorporated into the strategies. Feed to gain was improved (P < .05) by inclusions of reimplantation of estrogen and androgen combinations. Heifers were fed to heavier weights when androgens were included in the implant strategy. The percentage choice was reduced (P < .05) when estrogen plus androgen was used twice in the implant program when compared with single implant strategies. No differences for percentage yield grades 4 and 5 were detected in the nine implant strategies. Feeding of melengestrol acetate did not show an interaction with the nine implant strategies. Although there are complications with pooling data, the pooled analysis illustrated that heifers responded positively to implants containing androgen and estrogen.
Visceral fat measured by computed tomography and the risk of breast cancer

Background Obesity is a risk factor for the development of breast cancer, which can be examined to assess the association between abdominal fat distribution through computed tomography (CT) and risk of breast cancer by hormone receptor (HR) status in women. Methods We examined 234 cases of newly diagnosed breast cancer patients and 211 controls consisting of health examinees in the Republic of Korea. The abdominal body fat distribution was measured by CT scan. The subjects’ medical information, obtained from electronic medical records (EMR), were analyzed to verify the association between visceral fat and the type of breast cancer by HRs. Results While visceral obesity increased the risk of breast cancer in post-menopausal women by 1.50 (95% CI, 0.75–2.98), the effect was not observed in pre-menopausal women 0.86 (95% CI, 0.44–1.62). Also, histological grade was associated with visceral fat, which higher histological grade score (≥2) showed a slightly increased mortality rate (r=0.15, P=0.07). Patients with negative progesterone receptors tended to have a higher abdominal fat ratio than patients with positive progesterone receptors. Especially in pre-menopausal women, higher distribution of abdominal fat ratio in breast cancer patients had somewhat more of an effect on negative than positive HRs [estrogen receptor (ER), P=0.12; progesterone receptor (PR), P=0.06; human epidermal growth factor receptor 2 (HER2), P=0.43]. Conclusions Our results suggest that the clear association between breast cancer and distribution of abdominal fat, and the abdominal fat ratio, are useful indicators for risk factors for breast cancer as well as malignancy.
Stroke Localization: Clinical Correlation versus Findings of CTScan Brain in Patients Admitted at Liaquat UniversityHospital Hyderabad/Jamshoro -

OBJECTIVE: To study clinical localization of stroke and correlate with findings on C-T Scan of brain. DESIGN: Observational study. PLACE AND DURATION OF STUDY: The study was conducted at the Medical Department of Liaquat University Hospital Hyderabad/Jamshoro from January 2006 to December 2006. MATERIAL AND METHODS: Total 110 patients with features of stroke were included in this study. These patients were further evaluated for clinical correlation with findings on CT scan brain, done within 24 hours after the development of focal neurological deficit. Brain tumor, meningitis, viral or bacterial encephalitis, multiple sclerosis and metabolic derangements that could explain focal neurological deficit e.g hypoglycemia were` the exclusion parameters. RESULTS: Total of 110 patients, 60 (54.5%) were males and 50 (45.5%) were females. Age of patients ranged 22-84 years with mean±SD age of 53±5 years. On clinical ground cerebral infarction was suspected in 89 (80.9%) and cerebral hemorrhage in 21 (19.1%) patients. In 74 (83%) patients infarction was confirmed by CT scan brain, whereas cerebral hemorrhage was proved in 10 (47.6%) out of a total of 21 patients. These patients were further evaluated for clinical localization of area of stroke. Clinically left parietal / temporo parietal lobe infarction was suspected in 43 patients and right parietal / temporo parietal lobe in 25 patients. Left frontal lobe infarction in 7 patients right frontal lobe infarction in 8 patients, left internal capsule infarction in 2 patients and right internal capsule infarction in 4 patients. Comparing with the CT scan brain findings: left parietal / temporo parietal lobe infarction was confirmed in 41 (95.34%) patients, right parietal / temporo parietal lobe in 19 (76%), left frontal lobe in 5 (71.4%), right frontal lobe in 4 (50%), left internal capsule in 2 (100%) and right internal capsule in 3 (75%) patients. Left middle cerebral artery territory involvement was observed in 43 (58%) patients and right middle cerebral artery territory in 22(30%) patients. No Significant difference was observed in other cerebral artery territories. CONCLUSION: It was concluded from the study that cerebral infarction was more common than hemorrhage and middle cerebral artery territory infarction of both sides was more common than other cerebral artery territories. Localization of stroke on clinical basis is not always easy. Confident diagnosis requires careful case history taking, extensive neurological assessment and with the help of focal neurological deficit of a particular area. CATEGORY: Internal Medicine
The design guidelines for therapeutic sensory gardens.

The research topic is sensory, healing, rehabilitation and horticultural gardens, and the related discourses. The first part of the paper describes the historic development of the rehabilitation and health gardens in Latvia. Then he research paper takes a look at the main aspects which dominate in the rehabilitation and sensory visual and functional garden sites in the world. The quest to create contemporary landscape sites for health reasons is still one of the main subjects to explore and find definitions for. The methodology used in this paper is descriptive, from the perspective of historical relaxation gardens and health sites. The aim of this research is to define the main development lines of health sites in Latvia, trying to answer such questions as: How we can start developing sensory gardens and what is needed for their development in the future? To achieve the goal, it is necessary to absorb the world experience and exchange best practices, find innovative solutions, and adapt advanced rehabilitation center area landscapes to individual needs. When creating the healing gardens, the aesthetic and functional criteria have to be applied. Depending on the availability of the natural environment, health and satisfaction will be enhanced.
Whole-Food Plant-Based Lifestyle Program and Decreased Obesity: A 10-Year Follow-up

Failure of various weight-loss programs and long-term maintenance of favorable body composition in all kinds of people is high, since the majority go back to old dietary patterns. Many studies have documented the efficacy of a plant-based diet (PBD) for body mass management, but there are opinions that maintaining a PBD is difficult. We aimed to evaluate the long-term success of a whole-food plant-based (WFPB) lifestyle program. We investigated the differences in the obesity indices and lifestyle of 151 adults (39.6 ± SD 12.5 years), who were on our program for short (0.5–<2 years), medium (2–<5 years), or long term (5–10 years). Body-composition changes were favourable for all three groups, both genders and all participants. There were no differences in relative body-composition changes (BMI, body fat percentage and muscle mass index (MMI)) between the three groups. All participants improved their BMI (baseline mean pre-obesity BMI range (kg/m2): 26.4 ± 5.6 to normal 23.9 ± 3.8, p < 0.001), decreased body mass (–7.1 ± 8.3 kg, p < 0.001) and body fat percentage (–6.4 ± 5.6 % points, p < 0.001). 85.6% (101 out of 118) of parents of underage children (< 18 years), introduced WFPB lifestyle to their children. Those with the highest BMI at baseline lost the most of: a) BMI units, b) total body mass and c) body fat (a) (kg/m2) (–5.6 ± SD 2.9, –2.4 ± 1.8 and –0.9 ± 1.5), b) (kg) (–16.1 ± SD 8.8, –7.1 ± 5.4 and –2.5 ± 4.5) and c) (% points) (–9.5 ± SD 5.7, –6.6 ± 4.6 and –4.7 ± 5.3) for participants who had baseline BMI in obese, overweight and normal range, respectively; pbaseline vs. current < 0.001 for all). WFPB lifestyle program provides long-term lifestyle changes for reversal of obesity and is effective transferred to the next generation.
LNGFR (CD271) as Marker to Identify Mesenchymal Stem Cells from Different Human Sources: Umbilical Cord Blood, Wharton's Jelly and Bone Marrow

Bone marrow has been considered the main source for isolation of multipotent mesenchymal stem cells for therapeutic approaches. However, alternative sources of mesenchymal stem cells have been sought because their frequency and differentiating capacity decrease with age and because they are not easy to obtain from healthy donors. These cells have been also described both in umbilical cord blood and in Wharton’s jelly. To date, several studies have shown that CD271 is the most specific marker expressed of bone marrow mesenchymal stem cells before being cultured. The aim of this study was to determine whether it is possible to identify not cultured mesenchymal stem cells umbilical cord blood and Wharton’s Jelly using this marker, as well as to compare the results found to those obtained in bone marrow. Bone marrow, umbilical cord blood and Wharton’s Jelly cells suspension were analyzed by flow cytometry in order to identify the CD271+/CD45- population. Furthermore, we evaluated the potential to obtain mesenchymal stem cells from each source. Our results showed CD271+/CD45- cells in bone marrow samples, although this population did not appeared in umbilical cord blood nor from Wharton’s Jelly. However, the absence of this phenotype before culture samples had no relation with the ability to culture mesenchymal stem cells, specially taking into account that is was possible to obtain them from Wharton’s Jelly but not from umbilical cord blood. Our findings suggest that CD271 is not an adequate marker to identify mesenchymal stem cells from human umbilical cord before culture.
Paro y prestaciones: nuevos resultados para España

En este trabajo se estudia el efecto de las prestaciones por desempleo sobre el paro en Espana, destacando dos aspectos que pueden analizarse con las fuentes estadisticas disponibles. Primero revisamos y discutimos los resultados de un trabajo previo sobre la duracion del paro en que empleabamos datos de la Encuesta de Poblacion Activa durante 1987-1994, al hilo del cual discutimos varios aspectos relativos a la investigacion economica. En segundo lugar, presentamos nuevos resultados sobre el tiempo de paro con datos del Panel de Hogares de la Union Europea durante 1993-1999.
Relationship of age with periodontal diseases for males and females in Bangladesh; A hospital registry based cross-sectional observational study.

Periodontal diseases are the most commonly occurred diseases in the oral cavity with a widespread distribution around the globe. Variation in periodontal tissues associated with the aging and gender of the patient. The aim of this study was to determine relationship of age with periodontal diseases for males and females in Bangladeshi people. This study was conducted on 1837 patients visiting Department of Periodontology & Oral Medicine, Update Dental College & Hospital, from January 2017 to December 2018 (2 years) through a non-interventional cross-sectional method using descriptive and analytical statistics. Periodontal disease is the dependent variable of this study; patient age and gender serve as the independent variable. Total 37.5 % patients suffered from periodontitis and 62.5% suffered from gingivitis. Up to 48 years of age the prevalence of gingivitis was higher (70.64%) but periodontitis was more common (64.76%) in case of people over 48 years age. There is a significant (p<0.05) correlation between age and periodontal diseases exists in this study but no significant (p>0.05) correlation identified with gender. Distribution of periodontal diseases shows similar pattern between female (gingivitis=62.61%, periodontitis=37.53%) and male (gingivitis=62.47%, periodontitis=37.39%). Periodontal diseases are primarily correlating with the age but gender may not be associated. The most prevalent form of periodontal disease is gingivitis. Update Dent. Coll. j: 2019; 9 (2): 13-16
Comparaison of nutritionnal strategies targeting the nitric oxyde pathway to improve macrovascular function: a systematic review and a meta analysis

In endothelial cells, production of Nitric Oxide (NO) by NO synthase (NOS) lead to vasodilatation. In many pathologies associated with vascular dysfunction (diabetes, cardiovascular diseases, scleroderma…) this pathway is impacted. Our main outcome was flow mediated dilatation FMD, used as a surrogate of vascular efficiency and reflecting the endothelial NO release. We studied healthy participants to avoid confounding induced by pathological states. Predefined protocol was registered on PROSPERO (CRD42018090965) and followed PRISMA statement. We searched for double-blind randomized controlled trials (RCTs) in Medline and clinicaltrial.gov up to July 4th, 2018. Evaluated strategies were NOS substrates: L-arginine and L-citrulline, folic acids, inorganic nitrates and polyphenol, supplied by dietary ingredient or nutrient supplement. The secondary outcome was nitrate mediated dilatation (NMD). We performed two separate analysis on acute and chronic supplementation using mean difference and 95% confidence interval. 55 studies were included, 24 in acute and 38 in chronic supplementation. Acute and chronic efficiency of inorganic nitrates and polyphenols were significant on FMD. Among polyphenols, cocoa displayed the larger effect size. No significant result was found for NOS substrates, folic acids, for all on NMD and on placebo effect. Significant meta regression were on funding, duration of supplementation and smoking. The results were consistent in sensitivity analysis excluding low quality studies.
Survey of personal and educational characters in unsuccess medical students in compare with success students

Introduction: Educational failure and dropping out are among the major problems of higher education centers in the country. The present study was performed to compare personal and educational characters of success and unsuccessful medical students in the medical school of Kermanshah . Materials and Methods: Information about personal and educational characters were collected from all dropped out students, as unsuccessful group, and the students without dropping out and with a educational score more than 15, as control (success) group, during 2001 and 2005. Data analysis was carried out using SPSS software. To compare mean quantitative factors in two groups, in-depended T test and F test were used, chi-square and fisher test used for qualitative factors, and Pierson correlation coefficient calculated . Results: There was a significant difference between two successful and unsuccessful students groups with regard to age, sex, diploma score, time gap between graduation from high school and studying in university, parents education, marital status, students job, quota system and mean of all specialized lesson in Konkor examination (p<0.05). No significant difference was observed in the type of diploma and living in university accommodation between two groups . Conclusion: According to significant differences in many personal and educational characters between two successful and unsuccessful student groups, it seems more attention and special programming is necessary in this field .
Perceived Stress, Depression, and Coping Strategies in Patients with Sleep-Related Breathing Disorder

Sleep-related breathing disorders (SRBDs), such as obstructive sleep apnea and upper airway resistance syndrome, are characterized by repetitive upper airway obstructions during sleep. These diseases’ main symptoms are loud snoring, disrupted nocturnal sleep, and excessive daytime sleepiness. The course is usually progressive, and profound functional impairment and/or life-threatening complications can occur.1 According to recent, extensive population-based surveys on SRBDs, SRBD prevalence is relatively high, especially among obese middle-aged and older adults,2,3 and SRBDs constitute a major public health problem.4,5 A diagnosis of SRBD is stressful because of the disorder’s progressive course and associated significant physical and psychological distress. Many studies have documented that patients with SRBD experience mood changes, psychological dysfunction,6,7 and an impaired quality of life.8 Coping has been defined as “constantly changing cognitive and behavioral efforts to manage specific external and/or internal demands that are appraised as taxing or exceeding the resources of the person. ”9 Researchers view coping as a response to perceived stress and considered it to be particularly important for mediating life stresses and the onset of a psychiatric illness, especially depression.9 It has two widely-recognized major functions: regulating emotions or distress (emotion-focused coping) and managing the problem causing the distress (problem-focused coping). In most stressful encounters, individuals use both forms of coping apportioning the Received: May 15, 2011 Revised: July 19, 2011 Accepted: July 21, 2011
Evaluation of Self-reported Insomnia and Its Association with Some Geriatric Syndromes in Older Adults

Eur J Geriatr Gerontol 2019;1(1):11-16 Address for Correspondence: Banu Özulu Türkmen MD, İstanbul University İstanbul Faculty of Medicine, Department of Geriatrics, İstanbul, Turkey Phone: +90 533 029 78 22 E-mail: dr_banu84@hotmail.com ORCID: orcid.org/0000-0003-3492-874X Received: Feb 22, 2019 Accepted: Apr 17, 2019 This article was presented in 11th Academic Geriatric Congress and 14th the Eugms Congress as an oral presentation in 2018.