Miracle-dz/UniFAR-FTUs huggingface dataset:
The Acceptance Behavior of Smart Home Health Care Services in South Korea: An Integrated Model of UTAUT and TTF

With the COVID-19 pandemic, the importance of home health care to manage and monitor one’s health status in a home environment became more crucial than ever. This change raised the need for smart home health care services (SHHSs) and their extension to everyday life. However, the factors influencing the acceptance behavior of SHHSs have been inadequately investigated and failed to address why users have the intention to use and adopt the services. This study aimed to analyze the influential factors and measure the behavioral acceptance of SHHSs in South Korea. This study adopted the integrated model of the unified theory of acceptance and use of technology (UTAUT) and task–technology fit (TTF) to understand the behavioral acceptance of SHHSs from users’ perceptions and task–technology fit. Multiple-item scales were established based on validated previous measurement scales and adjusted in accordance with SHHS context. Data from 487 valid samples were analyzed statistically, applying partial least square structural equation modeling. The results indicated that the integrated acceptance model explained 55.2% of the variance in behavioral intention, 44.9% of adoption, and 62.5% of the continuous intention to use SHHSs, supporting 11 of the 13 proposed hypotheses. Behavioral intention was positively influenced by users’ perceptions on performance expectancy, effort expectancy, social influence, and functional conditions. Task–technology fit significantly influenced performance expectancy and behavioral intention, validating the linkage between the two models. Meanwhile, task characteristics were insignificant to determine task–technology fit, which might stem from complex home health care needs due to the COVID-19 pandemic, but were not sufficiently resolved by current service technologies. The findings implied that the acceptance of SHHSs needs to be evaluated according to both the user perceptions of technologies and the matching fit of task and technology. Theoretically, this study supports the applicability of the integrated model of UTAUT and TTF to the domain of SHHS, and newly proposed the measurement items of TTF reflecting the domain specificity of SHHS, providing empirical evidence during the pandemic era in South Korea. Practically, the results could suggest to the planners and strategists of home health care services how to promote SHHS in one’s health management.
Broadband infrared study of pressure‑tunable Fano resonance and metallization transition in 2H‑ MoTe 2

High pressure is a proven effective tool for modulating inter‑layer interactions in semiconducting transition metal dichalcogenides, which leads to significant band structure changes. Here, we present an extended infrared study of the pressure‑induced semiconductor‑to‑metal transition in 2H‑ MoTe 2 , which reveals that the metallization process at 13–15 GPa is not associated with the indirect band‑ gap closure, occurring at 24 GPa. A coherent picture is drawn where n‑type doping levels just below the conduction band minimum play a crucial role in the early metallization transition. Doping levels are also responsible for the asymmetric Fano line‑shape of the E 1 u infrared‑active mode, which has been here detected and analyzed for the first time in a transition metal dichalcogenide compound. The pressure evolution of the phonon profile under pressure shows a symmetrization in the 13–15 GPa pressure range, which occurs simultaneously with the metallization and confirms the scenario proposed for the high pressure behaviour of 2H‑ MoTe 2 . Transition Metal Dichalcogenides (TMDs) are layered crystals that exhibit a graphene-like lattice structure, with strong intra-layer covalent bonds and weak van der Waals forces between adjacent planes. Semiconducting TMDs have band gaps that are tunable with the number of layers 1–3 and span in the range of 1–2.5 eV depending on the crystal composition. In particular, 2H- MoTe 2 (hereinafter MoTe 2 ) displays an indirect band-gap E Ig ∼ 0.9 eV and a direct gap E Dg ∼ 1.1 eV 4 , which make it one of the few two-step mechanism that we proposed to describe the pressure-induced metallization process in MoTe 2 . At ambient pressure (P = 0 GPa), the n-type doping levels lie just below the conduction band minimum and the indirect gap energy is ∼ 0.9 eV. At P ∼ 13 to 15 GPa, we hypothesize an overlap between doping levels and conduction band, witnessed by the symmetrization of the Fano resonance, which is responsible for the metallic behavior of MoTe 2 observed in both FIR and transport measurements; in this configuration, however, the indirect gap is still open. Finally, at P ∼ 24 GPa, the indirect gap closes.
Burnout, Social Comparison Orientation and the Responses to Social Comparison among Teachers in The Netherlands

(1) Background: Teaching is a profession in which burnout constitutes a prevalent issue and provides ample opportunity to compare oneself with one’s colleagues, i.e., social comparison. The purpose of this research in the Netherlands was to examine responses to social comparison, in relation to burnout, and to individual differences in social comparison orientation (SCO). (2) Methods: Study 1 employed a retrospective measure to assess responses to social comparison. In Study 2, teachers were confronted with a scenario describing either a well or a poorly functioning colleague. (3) Results: Burnout was associated with more negative responses to well and to poorly functioning colleagues, with a less positive response to well-functioning colleagues. This last effect was fully due to the degree to which one identified or contrasted oneself with this colleague. Especially among high-SCO individuals, identification with a well-functioning colleague was accompanied by a positive affect. High-burnout individuals reported more identification with poorly functioning colleagues, and more contrast and less identification with well-functioning colleagues. Responses to well-functioning colleagues were more strongly related to burnout among those high in SCO. (4) Conclusions: An especially negative affect after comparison with well-functioning colleagues is typical for individuals high in burnout, particularly among individuals with a dispositional tendency to compare themselves with others.
Inflation meets neutrinos

Constraints on inflationary models typically assume only the standard models of cosmology and particle physics. By extending the neutrino sector to include a new interaction with a light scalar mediator ($m_{\phi}\sim$MeV), it is possible to relax these constraints, in particular via opening up regions of the parameter space of the spectral index $n_s$. These new interactions can be probed at IceCube via interactions of astrophysical neutrinos with the Cosmic Neutrino Background for nearly all of the relevant parameter space.
Causality between Domestic Investment and Economic Growth in Arab Countries

: The aim of this investigation is to examine the nexus between domestic investment and economic growth in Arab countries. To attempt our goal, we used annual data for the period 1990 – 2020 and Vector Error Correction Model. Empirical analysis indicates that there is no relationship between domestic investment and economic growth in the long run. However, we find a bidirectional causality between domestic investment and economic growth in the short run. These results provide evidence that domestic investment is necessary in Arab countries’ economy and is presented as an engine of growth since they cause economic growth in the short term. But they are not carried out and treated with a solid and fair manner, which offer new insights into Arabe countries’ investment policy for promoting economic growth.
3X2 ACHIEVEMENT GOALS AND PSYCHOLOGICAL MEDIATORS IN PHYSICAL EDUCATION STUDENTS METAS DE LOGRO 3X2 Y MEDIADORES PSICOLÓGICOS EN ESTUDIANTES DE EDUCACIÓN FÍSICA

This research examines the relationship between 3x2 achievement goals, basic psychological needs, self-determined motivation, intention to be physically active, and satisfaction with life. The sample was comprised of 1706 Physical Education students with aged between 10 and 17 years old ( M = 13.75; DT = 2.98). Descriptive analysis and linear regressions were performed. Validity and internal consistency were appropriate. The results pointed out the importance of competence and relationship satisfaction, self-determined motivation, and task-approach and other-approach goals in predicting the intention to be physically active, as well as task-based goals and satisfaction of the three basic psychological needs in predicting satisfaction with life. The 3x2 achievement goal framework is a relevant contribution in explaining the motivational and welfare consequences of the students. achievement goals: mastery-approach, mastery-avoidance, performance-approach, alphas Méndez-Giménez (task-avoidance) and . 89 (other-approach). The the degree of agreement with each of these using a 5-point Likert scale, which ranges from 1 all true for me) to (totally true for me).
Direct Reprogramming of Mouse Subchondral Bone Osteoblasts into Chondrocyte-like Cells

Treatment of full-thickness articular cartilage defects with exposure of subchondral bone often seen in osteoarthritic conditions has long been a great challenge, especially with a focus on the feasibility of in situ cartilage regeneration through minimally invasive procedures. Osteoblasts that situate in the subchondral bone plate may be considered a potentially vital endogenous source of cells for cartilage resurfacing through direct reprogramming into chondrocytes. Microarray-based gene expression profiles were generated to compare tissue-specific transcripts between subchondral bone and cartilage of mice and to assess age-dependent differences of chondrocytes as well. On osteoblast cell lines established from mouse proximal tibial subchondral bone, sequential screening by co-transduction of transcription factor (TF) genes that distinguish chondrocytes from osteoblasts reveals a shortlist of potential reprogramming factors exhibiting combined effects in inducing chondrogenesis of subchondral bone osteoblasts. A further combinatorial approach unexpectedly identified two 3-TF combinations containing Sox9 and Sox5 that exhibit differences in reprogramming propensity with the third TF c-Myc or Plagl1, which appeared to direct the converted chondrocytes toward either a superficial or a deeper zone phenotype. Thus, our approach demonstrates the possibility of converting osteoblasts into two major chondrocyte subpopulations with two combinations of three genes (Sox9, Sox5, and c-Myc or Plagl1). The findings may have important implications for developing novel in situ regeneration strategies for the reconstruction of full-thickness cartilage defects.
Evaluation of an Antigen Detection Rapid Diagnostic Test for Detection of SARS-CoV-2 in Clinical Samples

Antigen detection rapid diagnostic tests have been developed for first-line large-scale screening given their rapidity, simplicity, and accuracy. This study evaluates the diagnostic performance of an antigen detection rapid diagnostic test (BLOK BioScience, London, UK) detecting SARS-CoV-2 nucleocapsid protein. Serially diluted SARS-CoV-2 isolate and 110 NPS from COVID-19 patients were tested to determine the test’s sensitivity, and other viral isolates and 20 NPS from non-infected individuals were, for specificity, also tested. Ten clinical samples from COVID-19 patients with SARS-CoV-2 variants, including alpha, beta, gamma, delta, and eta variants, were collected to evaluate the test’s potential application in detecting emerging variants. Overall sensitivity was 92%, and stratifying into viral loads yielded 100% for Ct < 25 samples including SARS-CoV-2 variants, but 11.11% for Ct ≥30 samples. The analytical sensitivity of log10 TCID50/mL 2.0 was identified for SARS-CoV-2. Ninety-seven percent specificity with only SARS-CoV cross-reactivity lead to the Youden index of 0.89. The rapid diagnostic test has a high sensitivity for detecting SARS-CoV-2 in high viral load samples, possibly including emerging SARS-CoV-2 variants, but reduced sensitivity in low viral load samples suggests its optimized usage as a complementary testing method to other tests, including RT-PCR or a point-of-care test for large-scale screening, particularly for pandemic areas or airport border infection control.
Autoimmune Thyroid Disorders Are More Prevalent in Patients with Celiac Disease: A Retrospective Case-Control Study

Background. Among patients with celiac disease (CD), there is an increased incidence of autoimmune thyroid disorders (AITDs), with hypothyroidism being more frequent than hyperthyroidism. This retrospective case-control study aimed to explore the prevalence of TDs in a population of adult celiac patients from Northern Sardinia, a geographic area with a high prevalence of autoimmune disorders. Methods. Data were collected from consecutive patients with CD (cases) and without CD (controls) who were undergoing upper endoscopy and referred to a tertiary gastroenterology section of a teaching hospital (University of Sassari, Italy). Thyroid disorders were stratified as (i) autoimmune: including Hashimoto’s disease in euthyroidism or with hypofunction, and Graves’ disease; or (ii) non-autoimmune: thyroid nodules/goiter, iatrogenic thyroid hypo/hyperfunction, and thyroidectomy for any reason, including cancer. Results. Among a total of 8489 participants (females 5839, 64.7%) enrolled, there were 623 (7.3%) celiac patients and 7866 controls (92.7%). The overall frequency of TDs was 1177 (13.9%) and was higher (26.0%) in celiac patients than in controls (12.9%) (p < 0.001). The difference between AITDs (15.4% vs. 7.5%) and no-AITDs (2.7% vs. 1.1%) was statistically significant in CD patients compared with controls, respectively, and prevailed in the fifth and sixth decades. Hashimoto’s thyroiditis was more commonly associated with gland hypofunction. Odds ratios with their 95% confidence intervals (CIs) for the presence of AITDs were calculated, adjusting for sex, age, body mass index, smoking habits, occupation, and residence, and they were 2.387 (95% CI 1.857–3.068, p < 0.001) in CD patients, 5.855 (95% CI 4.434–7.731, p < 0.001) for female sex, and 1.012 (95% CI, 1.007–1.017, p < 0.001) for age. Conclusion. These results suggest the need for surveillance for TDs in patients with CD at onset and during follow-up.
Research of Maritime Object Detection Method in Foggy Environment Based on Improved Model SRC-YOLO

An improved maritime object detection algorithm, SRC-YOLO, based on the YOLOv4-tiny, is proposed in the foggy environment to address the issues of false detection, missed detection, and low detection accuracy in complicated situations. To confirm the model’s validity, an ocean dataset containing various concentrations of haze, target angles, and sizes was produced for the research. Firstly, the Single Scale Retinex (SSR) algorithm was applied to preprocess the dataset to reduce the interference of the complex scenes on the ocean. Secondly, in order to increase the model’s receptive field, we employed a modified Receptive Field Block (RFB) module in place of the standard convolution in the Neck part of the model. Finally, the Convolutional Block Attention Module (CBAM), which integrates channel and spatial information, was introduced to raise detection performance by expanding the network model’s attention to the context information in the feature map and the object location points. The experimental results demonstrate that the improved SRC-YOLO model effectively detects marine targets in foggy scenes by increasing the mean Average Precision (mAP) of detection results from 79.56% to 86.15%.
Comparison and Harmonization of Different Semi-Automated and Automated qRT-PCR Assays in the Assessment of SARS-CoV-2

In SARS-CoV-2 diagnostics, cycle threshold (Ct) values from qRT-PCRs semi-quantitatively estimate a patient’s viral load. However, relevant analytical differences between qRT-PCR assays are often neglected. This study was designed (i) to identify such differences between five commonly used assays and (ii) to demonstrate a straightforward strategy to harmonize them. QRT-PCRs for SARS-CoV-2 were carried out in 85 oropharyngeal swab samples using three fully automated (Alinity m, cobas®6800 and GeneXpert) and two semi-automated (genesig® and RIDA®GENE) assays. Qualitative results (positive/negative) showed excellent comparability between the fully automated assays, but not between the Alinity m and semi-automated methods. Ct values significantly varied between all the methods, with the median values ranging from 22.76 (Alinity m) to 30.89 (RIDA®GENE) and 31.50 (genesig®), indicating the lowest sensitivity for semi-automated methods. Passing–Bablok analysis further revealed systemic biases. Assay-specific viral load concentration calculations—based on generated individual standard curves—resulted in much better comparability between the assays. Applying these calculations, significant differences were no longer detectable. This study highlights relevant analytical differences between SARS-CoV-2 qRT-PCR assays, leading to divergent decisions about the mandatory isolation of infected individuals. Secondly, we propose a strategy to harmonize qRT-PCR assays to achieve better comparability. Our findings are of particular interest for laboratories utilizing different assays.
Recursive Constructions of Graphs of Large Girth and Given Degree

This paper is devoted to recursive constructions of small regular graphs of given degree 𝑘 and girth 𝑔 , called ( 𝑘,𝑔 ) -graphs, using Cayley graphs, perfect matchings and/or voltage graph constructions. First, we consider an analog of the canonical double cover construction, which produces ( 𝑘,𝑔 + 1) -graphs of even girth from ( 𝑘,𝑔 ) -graphs of odd girth by relying on Cayley graphs and/or voltage lifts. By considering Moore bounds, we show that there is no universal recursive construction of ( 𝑘,𝑔 + 1) -graphs from ( 𝑘,𝑔 ) -graphs of even girth 𝑔 that would produce graphs whose order is a constant multiple of the order of the original graph. Further, we introduce a novel approach for obtaining ( 𝑘 + 1 , 6) -graphs from ( 𝑘, 6) -graphs using perfect matchings and the voltage graph construction and compare our results with previously known results. We conclude our paper with a discussion of the potential of computer assisted searches relying on our constructions, and present a link between ( 𝑘, 6) -graphs and applications in communication systems.
THE FIRST STARS: A LOW-MASS FORMATION MODE

We perform numerical simulations of the growth of a Population III stellar system under photodissociating feedback. We start from cosmological initial conditions at z = 100, self-consistently following the formation of a minihalo at z = 15 and the subsequent collapse of its central gas to high densities. The simulations resolve scales as small as ∼1 AU, corresponding to gas densities of 1016 cm−3. Using sink particles to represent the growing protostars, we evolve the stellar system for the next 5000 yr. We find that this emerging stellar group accretes at an unusually low rate compared with minihalos which form at earlier times (z = 20–30), or with lower baryonic angular momentum. The stars in this unusual system will likely reach masses ranging from <1 M☉ to ∼5 M☉ by the end of their main-sequence lifetimes, placing them in the mass range for which stars will undergo an asymptotic giant branch (AGB) phase. Based upon the simulation, we predict the rare existence of Population III stars that have survived to the present day and have been enriched by mass overflow from a previous AGB companion.
Renal Medullary Carcinomas Harbor a Distinct Methylation Phenotype and Display Aberrant Methylation of Genes Related to Early Nephrogenesis

Simple Summary Renal medullary carcinomas (RMC) are aggressive tumors of the kidneys, characterized by a loss of SMARCB1. As the tumors, arising predominantly in young males with sickle cell trait, are very rare and no standard method for detection or treatment has been described, prognosis for these patients is poor. We generated methylation profiles of seven RMC samples and compared the hitherto unexplored methylation landscape of these tumors to other renal tumors and malignant rhabdoid tumors as well as epithelioid sarcomas, constituting two prototypically SMARCB1 aberrant entities. Based on these valuable datasets, we found that—in accordance with the previous gene expression data—RMCs separate from other SMARCB1 deficient entities. In a focused analysis of genes that are important for nephrogenesis, we particularly detected genes that govern early nephrogenesis to be hypomethylated and expressed at high levels in RMCs. Abstract Renal medullary carcinomas (RMC) are rare aggressive tumors of the kidneys, characterized by a loss of SMARCB1. Characteristically, these tumors arise in patients with sickle cell trait or other hemoglobinopathies. Recent characterization efforts have unraveled oncogenic pathways that drive tumorigenesis. Among these, gene sets that characterize replicative stress and the innate immune response are upregulated in RMCs. Despite comprehensive genetic and transcriptomic characterizations, commonalities or differences to other SMARCB1 deficient entities so far have not been investigated. We analyzed the methylome of seven primary RMC and compared it to other SMARCB1 deficient entities such as rhabdoid tumors (RT) and epithelioid sarcomas using 850 K methylation arrays. Moreover, we evaluated the differential gene expression of RMC using RNA-sequencing in comparison to other rhabdoid tumors. In accordance with previous gene expression data, we found that RMCs separate from other SMARCB1 deficient entities, pointing to a potentially different cell of origin and a role of additional genetic aberrations that may drive tumorigenesis and thus alter the methylome when compared to rhabdoid tumors. In a focused analysis of genes that are important for nephrogenesis, we particularly detected genes that govern early nephrogenesis such as FOXI1 to be hypomethylated and expressed at high levels in RMC. Overall, our analyses underscore the fact that RMCs represent a separate entity with limited similarities to rhabdoid tumors, warranting specific treatment tailored to the aggressiveness of the disease.