Miracle-dz/UniFAR-FTUs huggingface dataset:
Nile red-dye based analysis of synthetic fibres for forensic applications

Forensic evaluation of crime scenes normally involves examination of textile fibers, to find out the association between an individual and a crime scene, or between a suspect and a victim. The forensic samples normally include a mix of various types, sizes (micro to nano - scale) and shapes of natural and synthetic fibers, which are very difficult to differentiate/identify. Various sophisticated analytical instruments are being used to carry out the examination of these fibers. They involve various microscopy and spectroscopy based techniques, most of which are very complex and highly sensitive. Further, they may require a series of sample preparation steps to get high selectivity and are highly time consuming. Here we report a fluorescence microscopy based synthetic (plastic) fiber detection method using Nile Red (NR) dye, which provides high selectivity for synthetic fibers. The methodology involves the use of NR dye which selectively stains the fibers collected on filter papers following separation from samples/soils and water. The selectivity of NR towards the fibers is due to their non-polar property. Binding with NR makes the fibers fluoresce when viewed under a fluorescence microscope. This selectivity of NR for fibers makes the identification of fibers lot easier and less timeconsuming in forensic samples when compared to the more commonly used optical microscopy (where the presence of naturally-occurring substances of similar size can result in more errors). The paper will discuss optimisation of various parameters and method validation for detection of synthetic fibers and microplastics from soil samples. As an example, our method has shown to provide distinct clarity for the analysis of microfibers. The potential for the application of the method for faster forensics analysis will be discussed.
SERUM THYROXINE AND TRIIODOTHYRONINE CONCENTRATIONS PRIOR TO AND AFTER DELIVERY IN PRIMIPAROUS HOLSTEIN COWS

Serum thyroxine (T4) and triiodothyronine (T3,) concentrations were determined twice daily (8 and 16h) in seven primiparous Holstein cows from 4 days prior to (-4, -3, -2, -1) to delivery, on the day of calving, and up to 4 days postpartum (1, 2, 3, 4) by radioimmunoassay (RIA). Serum thyroid hormone concentrations were higher in the afternoon samples on the first two days of investigation (-4 and -3), but this circadian rhythm was notmaintained. Serum thyroid hormones declined significantly after delivery according to a polynomial regression line (R = O.967 for T4,' R = O.9216 for T3).
Reduction in Symptoms Related to Parkinson's Disease Concomitant with Subluxation Reduction Following Upper Cervical Chiropractic Care

Objective: To provide a detailed report on one case of a 67 year-old female with Parkinson’s disease under upper cervical chiropractic care. Clinical Features: A 67 year-old female patient presenting to a private practice with an atlas subluxation complex as well as signs and symptoms of Parkinson’s disease that include weakness, tremors, scoliosis and rigidity. Intervention and Outcomes: Over a period of 6 months, the patient was seen 19 times and was adjusted 12 times following the NUCCA protocol. Improvements in radiographic measurements, paraspinal thermography, and sEMG were recorded. Patient self-reported improvements in weakness, tremors, rigidity, and overall mobility. Conclusion: The upper cervical subluxation may be a contributing factor to the symptomatic expression of Parkinson’s disease. Reduction of the subluxation with specific vectored correction may be a plausible, safe, and effective approach for managing PD. More research is warranted investigating the effects of upper cervical care and Parkinson’s Disease (PD).
Statistics

returned; or (allowing for disturbing causes) 1 in every 1500 inhabitants. The proportion in all Europe is 1 in every 1593 persons. In Ireland it varies in different parts:? 1 in 1794, in Leinster; 1 in 16S9, in Connaught; 1 in 1487, in Ulster; 1 in 1469, in Munster. It is more common in the rural than in the civic portions; and in the hilly than the flat districts. Of the whole number, 4151 were deaf and dumb; and of these, 2349 were males, and 1802 females,? or 100 men to 76'G1 females. 334 were dumb but not deaf. Deaf-and-dumb persons do not directly engender deaf-and-dumb children: thus, in 77 cases, one parent, and in 5^ instances both parents, were deaf and dumb; only two mute children resulted. Yet muteism is often manifest in several members of a family derived from a com'mon, though not a deaf-and-dumb stock. Thus, 2512 families had one mute child; 287, two . mutes; 127, three mutes; 32, four mutes; 8, five mutes; 3, six mutes; 1, seven mutes; 1, eight mutes. On inquiry, also, it is found that hereditary predisposition from ancestors could be traced in 281 cases; in 119 of which the taint descended through the father's side, and in 132 through the mother's.
Service quality in higher education: management student's perspective

According to some scholars, the strategic success of a service organization depends on its ability to consistently meet or exceed customer service expectations. This study thus set out measure the service quality performance of a faculty in a public university. Based on stratified random sampling on 229 students employing a survey instruments that measure six dimensions of quality attributes, the result of the study revealed that the level of service quality in this particular faculty is moderate. Analysis showed that there are significant differences based on the studentsâ€™ perception of this faculty service quality by year of study and race. However, there are no significant differences based on courses and gender. Further, no significant relationship was found between studentsâ€™ academic performance and evaluation of survice quality. Implication and limitation of the study are highlighted and further research discussions are suggested.
Breakthrough

Book comes with the new information and lesson every time you read it. By reading the content of this book, even few, you can gain what makes you feel satisfied. Yeah, the presentation of the knowledge by reading it may be so small, but the impact will be so great. You can take it more times to know more about this book. When you have completed content of breakthrough, you can really realize how importance of a book, whatever the book is
Letters to the Editor

We therefore think that the controversy regarding the cervical components of headache is not solved by simply suggesting involvement of the greater occipital nerve. It seems to us much more attractive to expand Olesen's new concept (2). This author in fact simply states that headache is due to an excess of input. It is not unlikely that this excess of input will on occasion excite neurons in adjoining areas of the cord, both rostrally and caudally.
Spatial Demixing of Ring and Chain Polymers in Pressure-Driven Flow

We investigate mixtures of ring and linear polymers in solution at various number ratios, ranging from pure chains to pure rings, and at densities around the overlap concentration. In bulk and at rest, we find a shrinking of both topologies with increasing polymer content of the solution. At the same time, we observe an increase in the solution viscosity with a concomitant reduction of the polymer diffusivity. When exposing ring-chain mixtures of any composition to a pressure-driven flow in a slit channel, we find that ring polymers always migrate toward the center, whereas chains populate the regions of high local shear close to the channel walls. Interestingly, in a pure chain solution, this cross-stream migration toward the walls is absent. This phenomenon could be used to iteratively separate chains and rings at high mass throughput in simple microfluidic devices using pressure-driven flows. Furthermore, we show how pressure-driven flow can be used as a computationally efficient approach for determini.
Perceptions of adults with spinal cord injury on the skills for daily activities and health indicators in the light of noc: descriptive research

Objective : Verify the perception of adults with spinal cord injury (SCI) on their skills for daily activities and pair data with health indicators in the light of NOC. Method : Cross-sectional study, census and quantitative, conducted in 2008 in UBSF's Campina Grande-PB. 47 people have taken part as sample, who answered a form with indicators domain of the Functional Health of NOC and an Questionnaire A, composed by questions about abilities to perform daily activities. It was performed a pairing between the instruments and used the SPSS to analyze data. Results : Cronbach Alpha was 0.752. The items that showed more commitment were: Management of money (80.8%), sexual performance (74%), Leisure (68%), Labor (55%) and ambulation (45%) - p < 0.001. Conclusion : There is impairment on the participants' skills for daily activities. Nurses can help them develop actions of health education and research that contribute to improving public policies for those people.
Bioavailability of some amoxycillin capsules marketed in Thailand

A six-way crosso er study was conducted in six healthy male volunteers to evaluate the relative bioavailability of six different marketed 250 mg amoxycillin capsules. Each dose was administered as a single 2x250 mg capsules after an overnight fast, and periodically blood samplcs were obtained for 8 hours. Serum levels af amoxycillin were determined by standard microbiological cylinder plate method using Micrococ us luteus (ATCC 9341> as the test organism. In Ihis sludy, the Amoxil-Bencard, the innovator s brand was used as the reference. The pharmacokinetic parameters of each product were determined. Statistical analysis (ANOVA and Fisher's pairing t test ) of the resultsindicated that one of the products tested was not significantly different (p> 0.05) in its bioavailability compared to Amoxil-Bencard while the other four products were significantly different (p<0.05)
Towards a Better Understanding of Beige Adipocyte Plasticity

Beige adipocytes are defined as Ucp1+, multilocular adipocytes within white adipose tissue (WAT) that are capable of thermogenesis, the process of heat generation. In both mouse models and humans, the increase of beige adipocyte population, also called WAT browning, is associated with certain metabolic benefits, such as reduced obesity and increased insulin sensitivity. In this review, we summarize the current knowledge regarding WAT browning, with a special focus on the beige adipocyte plasticity, collectively referring to a bidirectional transition between thermogenic active and latent states in response to environmental changes. We further exploit the utility of a unique beige adipocyte ablation system to interrogate anti-obesity effect of beige adipocytes in vivo.
Combined Effect of Sarcopenia and Systemic Inflammation on Survival in Patients with Advanced Stage Cancer Treated with Immunotherapy

Abstract Background Sarcopenia and inflammation have been associated with poor survival in patients with cancer. We explored the combined effects of these variables on survival in patients with cancer treated with immunotherapy. Methods We performed a retrospective review of 90 patients enrolled on immunotherapy‐based phase I clinical trials at Emory University from 2009 to 2017. Baseline neutrophil‐to‐lymphocyte ratio, monocyte‐to‐lymphocyte ratio, and platelet‐to‐lymphocyte ratio (PLR) were used as surrogates of inflammation. The skeletal muscle index (SMI) was derived from the skeletal muscle density calculated from baseline abdominal computed tomography images. Optimal cutoffs for continuous inflammation biomarkers and SMI were determined by bias‐adjusted log‐rank test. A four‐level risk stratification was used to create low‐risk (PLR <242 and nonsarcopenic), intermediate‐risk (PLR <242 and sarcopenic), high‐risk (PLR ≥242 and nonsarcopenic), and very‐high‐risk (PLR ≥242 and sarcopenic) groups with subsequent association with survival. Results Most patients (59%) were male, and the most common cancers were melanoma (33%) and gastrointestinal (22%). Very high‐risk, high‐risk, and intermediate‐risk patients had significantly shorter overall survival (hazard ratio [HR], 8.46; 95% confidence interval [CI], 2.65–27.01; p < .001; HR, 5.32; CI, 1.96–14.43; p = .001; and HR, 4.01; CI, 1.66–9.68; p = .002, respectively) and progression‐free survival (HR, 12.29; CI, 5.15–29.32; p < .001; HR, 3.51; CI, 1.37–9.02; p = .009; and HR, 2.14; CI, 1.12–4.10; p = .022, respectively) compared with low‐risk patients. Conclusion Baseline sarcopenia and elevated inflammatory biomarkers may have a combined effect on decreasing survival in immunotherapy‐treated patients in phase I trials. These data may be immediately applicable for medical oncologists for the risk stratification of patients beginning immunotherapeutic agents. Implications for Practice Sarcopenia and inflammation have been associated with poor survival in patients with cancer, but it is unclear how to apply this information to patient care. The authors created a risk‐stratification system that combined sarcopenia and platelet‐to‐lymphocyte ratio as a marker of systemic inflammation. The presence of sarcopenia and systemic inflammation decreased progression‐free survival and overall survival in our cohort of 90 patients who received immunotherapy in phase I clinical trials. The data presented in this study may be immediately applicable for medical oncologists as a way to risk‐stratify patients who are beginning treatment with immunotherapy.
Is parity a cause of tooth loss? Perceptions of northern Nigerian Hausa women

Background Reproduction affects the general health of women, especially when parity is high. The relationship between parity and oral health is not as clear, although it is a widespread customary belief that pregnancy results in tooth loss. Parity has been associated with tooth loss in some populations, but not in others. It is important to understand the perceptions of women regarding the association between parity and tooth loss as these beliefs may influence health behaviors during the reproductive years. Aim To explore the views of Hausa women regarding the link between parity and tooth loss. Methods Qualitative data were collected through a grounded theory approach with focus group discussions (FGDs) of high and low parity Hausa women (n = 33) in northern Nigeria. Responses were elicited on the causes of tooth loss, effects of tooth loss on women’s quality of life, issues of parity and tooth loss, and cultural beliefs about parity and tooth loss. The data were analyzed thematically using ATLAS-ti. Results Respondents associated tooth loss with vomiting during labor, a condition termed ‘payar baka’. Poor oral hygiene, excessive consumption of refined carbohydrates, tooth worm, cancer and ageing were also believed to cause tooth loss. The greatest impacts of tooth loss on the lives of the respondents were esthetic and masticatory changes. Conclusion Respondents perceived that parity is indirectly linked to tooth loss, as reflected in their views on the association between vomiting during labor and tooth loss.
A simultaneous X-ray diffraction–differential scanning calorimetry study into the phase transitions of mefenamic acid

In this study, the polymorphic transitions of mefenamic acid (MA) were studied by synchrotron X-ray powder diffraction combined with differential scanning calorimetry (XRD-DSC). The initial material was found to be phase-pure form I which, when heated, produces two endotherms that can be observed by DSC at 162.72 and 219.55°C. The former was found to correspond to a solid–solid enantiotropic transition from form I to a mixture of forms II and III. The latter is the melting point of form II. As form I is heated, significantly greater unit-cell expansion is seen in the a direction than in b and c, which can be explained by the stronger intermolecular interactions in the bc plane. Refinements of the reported MA structures against the patterns collected during heating revealed that at 175°C there exists a mixture of forms I, II and III, whereas only forms II and III remain at 205°C. However, reflections are observed at both temperatures which cannot be fitted with the known forms of MA. It is hypothesized that a new form of MA is produced upon heating. The stability of MA after the enantiotropic transition temperature is II > III > I, which differs from the previously reported II > I > III.
Work-life balance of female PhD students in engineering

In spite of tremendous efforts, women are still under-represented in science.1 Their proportion compared to men is already lower in tertiary education and it further decreases in Research and Development (R&D) where we hardly find any women in top positions (She Figures, 2012). Reasons are multifaceted. Problems often start in the educational system, where women are often discouraged from choosing a science career. Their interest towards science starts to decrease during elementary school. Later, even those who chose ‘A’ level STEM courses at high school tend to apply for less male-dominated majors at university, such as biology or pharmacology; or they shift to social science and humanities (Paksi, 2014). The ‘academic pipeline’ is leaking during later career stages as well, and loses women to a greater extent than men. It is well documented that professional women tend to leave science mainly after obtaining their PhD (Etkowitz et al., 2000).
Reducing Postoperative Blood Loss Following Total Hip Replacement: A New Protocol Using Rivaroxaban And Tranexamic Acid

Blood loss following total hip replacement is a major contributor to increase morbidity and length of stay. Various techniques have been described to reduce its occurrence. We now follow a set protocol, combining rivaroxaban for thrombo-prophylaxis and tranexamic acid to reduce immediate postoperative bleeding. Patients and methods: Using data collected prospectively we looked at 2 groups of consecutive patients undergoing THR. The protocol was the only factor changed during the period studied. Initially we used subcutaneous dalteparin injections and continued use of aspirin in peri-operative period following total hip replacements (Group I–317 patients). A new protocol was introduced involving rivaroxaban for thrombo-prophylaxis with its first dose at least 8 hours from skin closure and stopping aspirin at least 7 days before operation. In addition tranexamic acid was given in a dose of 500 mg (or 1 gm in obese patients) intravenously just prior to incision (Group II–348 patients). We compared these two groups regards Hb drop at 24 hours and blood transfusion requirement. Results: The average Hb drop at 24 hours postop in group I was 3.08 gm/dl compared to 2.31 in group II. (p There was no increase in number of DVT/PE, but the sample size was too small to assess this statistically. Conclusion: This protocol drastically reduces requirement of postoperative blood transfusion requirement helping in reducing the length of stay following hip replacements.
Hypertension and Neuroimaging Changes After Bevacizumab for Retinopathy of Prematurity

We review the development of new-onset hypertension in a 9-week-old, formerly extremely premature infant after administration of intravitreal bevacizumab for treatment of ROP. Bevacizumab is a human monoclonal immunoglobulin G1 antibody to vascular endothelial growth factor indicated in several adult diseases. Emerging literature and expert opinion support the off-label use of intravitreal bevacizumab in the treatment of retinopathy of prematurity (ROP), a common disease process seen in premature neonates. One of the most common side effects of systemic therapy in adults is hypertension; however, this has not been well described in infants receiving bevacizumab for ROP. In this report, we review a case of a former 25-week premature infant treated for stage 3 ROP with administration of intravitreal bevacizumab. The immediate posttreatment course was uncomplicated; however, at 10 days posttreatment, he developed new-onset systemic hypertension. In addition, neuroimaging revealed new areas of vasogenic edema, which improved over time. To the best of our knowledge and after a review of the literature, neither of these effects has been described in neonates after intravitreal bevacizumab for ROP.
The utilizing of zeolite and manures for increasing potassium availability, uptake, and yield on soybean in Alfisols

Enhancement soybean production is needed to fulfill its high demand in Indonesia by utilizing the widespread potential land, such as Alfisols. Zeolite and manure addition used to overcome the nutrient availability in Alfisols and decrease the use of inorganic fertilizer. This study was conducted in field condition in a factorial randomized complete block design with three replicates in an Alfisols aimed to assess the effect of applying three rates of zeolites (Z0: 0 t.ha−1, Z1: 2.5 t.ha−1 and Z2: 5 t.ha−1) and three types of 5 t.ha−1 manures (P0: 0 No Manure, P1: quail manure (5 t.ha−1), P2: cattle manure (5 t.ha−1)) on K availability, its uptake, number of pods and seed weight/plot on soybean [Glycine max. (L) Merrill]. Zeolites showed a significant result of potassium availability at the rate 5 t.ha−1. The similar result is given by cattle manure for potassium uptake in soybean. An interaction between zeolites at the rate 5 t.ha−1 and cattle manure showed the significant result on a number of pods.plant−1, 100-seeds weight and seed yield.
Trastuzumab plus adjuvant chemotherapy for human epidermal growth factor receptor 2 (HER2)-positive early-stage breast cancer: A real-world retrospective study in Chinese patients

Objective To assess the long-term effectiveness and safety of trastuzumab in adjuvant therapy for Chinese patients with early-stage human epidermal growth factor 2 (HER2)-positive breast cancer in a real-world setting. Methods This retrospective observational study analyzed the medical records of HER2-positive breast cancer patients between 2000 and 2012 at the Chinese Academy of Medical Sciences. Patients who received adjuvant chemotherapy alone or adjuvant chemotherapy followed by/combined with trastuzumab were included. The Kaplan-Meier method was used to estimate disease-free survival (DFS) and overall survival (OS). Hazard ratios (HR) and 95% confidence intervals (95% CI) were calculated using the Cox regression model. Results Of the 1,348 patients analyzed, 909 received chemotherapy alone and 439 received chemotherapy plus trastuzumab. The 3-year, 5-year and 10-year DFS rates were 83.70%, 76.38% and 68.94%, respectively, in the chemotherapy-alone cohort, and 90.21%, 86.19% and 83.45% in the chemotherapy plus trastuzumab cohort. The 3-year, 5-year and 10-year OS rates were 96.10%, 91.40% and 81.88% in the chemotherapy-alone cohort, and 98.17%, 94.91% and 90.01% in the chemotherapy plus trastuzumab cohort. The chemotherapy plus trastuzumab group had a significantly lower risk of disease recurrence and death than the chemotherapy-alone group (DFS: HR=0.50, 95% CI, 0.37−0.68; P<0.001; OS: HR=0.53, 95% CI, 0.34−0.81; P=0.004) after adjusting for covariates. In the 439 patients treated with trastuzumab, multivariate analysis suggested that lymph node positivity, higher T stages, and hormone receptor-negative status were significantly associated with higher risks of disease recurrence, and lymph node positivity and hormone receptor-negative status were significantly associated with higher risks of death. Grade 3/4 adverse events (incidence ≥1%) were more common in patients receiving trastuzumab (54.44%vs. 15.73%). Conclusions Early-stage HER2-positive breast cancer patients treated with trastuzumab plus adjuvant chemotherapy have a significant survival benefit compared with chemotherapy-alone in real-world settings. Lymph node positivity, hormone receptor-negative status, and higher T stages may be associated with higher risks of recurrence, and effective therapy for patients with these factors is required.