Miracle-dz/UniFAR-FTUs huggingface dataset:
Application of Activity Trackers among Nursing Home Residents—A Pilot and Feasibility Study on Physical Activity Behavior, Usage Behavior, Acceptance, Usability and Motivational Impact

The aim of this study was to assess physical activity and sedentary behavior, as well as the usage behavior, usability, acceptance, and motivational impact of an applied activity tracker among nursing home residents. Physical activity and usage behavior were measured among 22 residents (68 to 102 years) by use of a commercial activity tracker worn during waking hours for 77 days on average. Usability, acceptance, and motivational impact of the tracker were examined using an adapted questionnaire. Participants walked, on average, 1007 ± 806 steps per day and spent, on average, more than 9 h (77.2% of their waking time) sedentary. The average steps/day increased significantly within the first five weeks of wearing the activity tracker. The acceptance rate was high (94.4%). The tracker was used for 65.4% of the individual study period, and usage behavior did not significantly change during the first five wearing weeks. Participants with a usage time of ≥50% walked significantly more steps per day than those with a lower usage. Overall, we were able to reveal that the residents were highly inactive and sedentary. The results support the feasibility of a long-term application of activity trackers to assess or even increase physical activity behavior.
Subjective social status and inflammation: The role of culture and anger control.

OBJECTIVE Research on subjective social status (SSS) and inflammation risk suffers from a lack of cross-cultural data as well as inconsistent findings between SSS and the biomarker C-reactive protein (CRP). The current study addressed these issues by examining possible cultural differences in the SSS-CRP link with anger control as an underlying mechanism while controlling for potential confounds such as wealth, education, and health factors. METHOD Participants comprised 1,435 adults from the Biomarker Project of the MIDUS (American) and MIDJA (Japanese) studies. Participants' SSS and tendency to control anger were assessed through surveys, and their CRP levels were measured through fasting blood samples. RESULTS Results showed that for Americans, CRP levels increased as SSS decreased, but for the Japanese, there was no relationship between SSS and CRP. Furthermore, this moderating effect of culture was mediated by anger control such that Americans controlled their anger less as SSS decreased, which then predicted higher levels of CRP, whereas the Japanese controlled their anger less as SSS increased, but this relationship did not predict CRP levels. These findings were specific to anger control (and not other varieties of anger) and robust to adjustment for a variety of potential confounds. CONCLUSIONS Our findings demonstrate that culture exerts a moderating effect on the relationship between SSS and CRP, and this effect occurs through cultural differences in how SSS relates to anger control. The current study also highlights the need to consider cultural factors and psychosocial processes in further research on SSS and health. (PsycInfo Database Record (c) 2020 APA, all rights reserved).
ASSESSING NURSES’ SATISFACTION ON THEIR WORK-SCHEDULES: THE CASE OF A HOSPITAL IN JAKARTA

Background: Nurses’ low satisfaction in their work may affect their performance in providing health services. Reports have noted that nurses’ work satisfaction in several hospitals in Indonesia have been below the minimum service standard (90%). Many factors can affect the nurses’ satisfaction in their work, including their work schedules. Objectives: This study aims to determine the association between nurses’ work satisfaction and their work schedules. Methods: This is a cross-sectional study which used the survey to collect data from a group of nurses who were attached to a public hospital in Jakarta. The samples (n=127 nurse) were selected through stratified random sampling based on the determined inclusion criteria. The instrument used to evaluate the satisfaction was the Mines Job Satisfaction Scale (MNPJSS) while the instrument used to evaluate the nurses’ scheduling was developed by the authors. Pearson’s correlation was applied in the analysis. Results: The mean score of the nurses’ satisfaction was 60.2% while the mean score for the nurses’ scheduling was 76.2%. The results also indicated a positive significant correlation between nurses’ scheduling with nurses’ satisfaction (p-value = 0.001), with a moderate strength of correlation (r = 0.421). The nurses’ satisfaction rate in their work within the hospital involved in this study was lower than the minimum standard rate for hospitals in Indonesia. The nurses’ highest dissatisfaction was with their salary (59.1%) followed by their career development (38.5%). Although the nurses’ scheduling had been implemented, it seems that factors such as nurse to patient ratio and nurses’ mixed level of skills had not been fully considered in the scheduling. As the score of the nurses’ scheduling increased, the satisfaction rate among the nurses also climbed higher. Conclusion: The nurses’ satisfaction in their work was affected by the nurses’ scheduling duties, thus hospital managers need to manage the nurses’ scheduling appropriately so as to improve their work satisfaction.
Testing models of reciprocal relations between social influence and integration in STEM across the college years

The present study tests predictions from the Tripartite Integration Model of Social Influences (TIMSI) concerning processes linking social interactions to social integration into science, technology, engineering, and mathematics (STEM) communities and careers. Students from historically overrepresented groups in STEM were followed from their senior year of high school through their senior year in college. Based on TIMSI, we hypothesized that interactions with social influence agents (operationalized as mentor network diversity, faculty mentor support, and research experiences) would promote both short- and long-term integration into STEM via social influence processes (operationalized as science self-efficacy, identity, and internalized community values). Moreover, we examined the previously untested hypothesis of reciprocal influences from early levels of social integration in STEM to future engagement with social influence agents. Results of a series of longitudinal structural equation model-based mediation analyses indicate that, in the short term, higher levels of faculty mentorship support and research engagement, and to a lesser degree more diverse mentor networks in college promote deeper integration into the STEM community through the development of science identity and science community values. Moreover, results indicate that, in the long term, earlier high levels of integration in STEM indirectly influences research engagement through the development of higher science identity. These results extend our understanding of the TIMSI framework and advance our understanding of the reciprocal nature of social influences that draw students into STEM careers.
Effect of GH p.L127V Polymorphism and Feeding Systems on Milk Production Traits and Fatty Acid Composition in Modicana Cows

Simple Summary Growth hormone (GH) participates in the regulation of lactation and lipid metabolism. Milk traits and fatty acid composition were investigated in Modicana cows, in relation to the genetic polymorphism at GH locus p.L127V and its interaction with the feeding system. It has been compared 8 hours of grazing without concentrate (EX), versus 2 h of grazing with concentrate (SI). The frequencies of LL, LV and VV genotypes were, respectively, 0.64, 0.34, 0.02. The GH polymorphism and its interaction with feeding system did not influence milk yield and gross composition. LL cows showed higher levels of total unsaturated and monounsaturated fatty acids, thus suggesting a potential role of the GH polymorphism on improving the healthy quality of milk. A higher level of 18:1 in the LL cows was evident only in the extensive system. The lower energy input in the extensive system, compared to the semi-intensive system, could justify this result. Abstract Growth hormone participates in the regulation of lactation and lipid metabolism. A trial study was conducted to evaluate the effects of genetic polymorphism at GH p.L127V and its interaction with feeding system (extensive, EX; semi-intensive, SI) on milk traits and fatty acids composition in Modicana cows. In the semi-intensive farm (SI) diet consisted of hay, concentrate and 2 h of grazing. In the extensive farm (EX) feeding consisted in 8 h of grazing and hay. The frequencies of LL, LV and VV genotypes were, respectively: 0.64, 0.34, 0.02. GH polymorphism and its interaction with feeding system did not influence milk yield and composition. Cows carrying LL genotype produced milk with lower 6:0 and 8:0 and higher 16:1 c9 and 18:1 c9, total UFA and total MUFA. Feeding significantly affected fatty acids: in EX cows lower SFA and higher PUFA and UFA were found, compared to SI cows. The lower, more favorable atherogenic index of milk from EX system was coherent with the improved healthy characteristics of milk from animals fed almost exclusively on pasture. A significant interaction genotype x feeding system was evident for 18:1, higher in the LL cows only in the EX system, but not in the SI system.
4D flow MRI for non-invasive measurement of blood flow in the brain: A systematic review

The brain’s vasculature is essential for brain health and its dysfunction contributes to the onset and development of many dementias and neurological disorders. While numerous in vivo imaging techniques exist to investigate cerebral haemodynamics in humans, phase-contrast magnetic resonance imaging (MRI) has emerged as a reliable, non-invasive method of quantifying blood flow within intracranial vessels. In recent years, an advanced form of this method, known as 4D flow, has been developed and utilised in patient studies, where its ability to capture complex blood flow dynamics within any major vessel across the acquired volume has proved effective in collecting large amounts of information in a single scan. While extremely promising as a method of examining the vascular system’s role in brain-related diseases, the collection of 4D data can be time-consuming, meaning data quality has to be traded off against the acquisition time. Here, we review the available literature to examine 4D flow’s capabilities in assessing physiological and pathological features of the cerebrovascular system. Emerging techniques such as dynamic velocity-encoding and advanced undersampling methods, combined with increasingly high-field MRI scanners, are likely to bring 4D flow to the forefront of cerebrovascular imaging studies in the years to come.
Usability of mental illness simulation involving scenarios with patients with schizophrenia via immersive virtual reality: A mixed methods study

Objectives Schizophrenia is one of the most prevalent mental illnesses contributing to national burden worldwide. It is well known that mental health nursing education, including clinical placement, is still insufficient to reach the optimal level of competency in nursing students. This study suggests a new form of mental health virtual reality (VR) simulation that is user-friendly and engaging to improve education about schizophrenia, thereby improving its treatment. Method A mixed-methods study was conducted with a total of 60 nursing students, using 360-degree videos of five different scenarios reflecting clinical symptoms of schizophrenia patients and related treatment tasks delivered via head-mounted displays (HMDs). We used a 17-item quantitative questionnaire and a 7-item open-ended qualitative questionnaire to evaluate the ease of use and usefulness of the VR simulation program and to identify areas where further improvement is required. Results The VR simulation program was perceived as useful and exciting. Participants stressed that the high realism of the simulation increased their engagement in and motivation to learn about mental health nursing. Some participants made suggestions, such as further refining the picture and sound quality in order to achieve satisfactory educational outcomes. Conclusion VR simulation using 360-degree videos and HMDs could serve as an effective alternative form of clinical training in mental health nursing. Education could be enhanced by its benefits of being engaging and exciting, as reported by this study’s participants.
Occurrence of Salmonella enterica, subspecies enterica serovar Berta (Salmonella Berta) in bovine calves, in Himachal Pradesh, India

Salmonellosis is an important zoonotic disease of economic significance. It infects both man and animals alike around the globe. Salmonella enterica, subspecies enterica serovar Berta (9,12 : f, g, t : -) was isolated from three out of five blood samples of 3-6-month-old ailing calves. The isolates were sensitive to ciprofloxacin, enrofloxacin, ofloxacin and moderately sensitive to gentamicin, lomefloxacin, oxytetracyclines, tetracyclines, but refractory to ampicillin and penicillin. Treatment with enrofloxacin resulted in cent per cent recovery. The infection might have been picked up by calves from poultry birds reared in the same premises.
Trends and Predictors of COVID-19 Information Sources and Their Relationship With Knowledge and Beliefs Related to the Pandemic: Nationwide Cross-Sectional Study

Background During the COVID-19 pandemic, there is a heightened need to understand health information seeking behaviors to address disparities in knowledge and beliefs about the crisis. Objective This study assessed sociodemographic predictors of the use and trust of different COVID-19 information sources, as well as the association between information sources and knowledge and beliefs about the pandemic. Methods An online survey was conducted among US adults in two rounds during March and April 2020 using advertisement-based recruitment on social media. Participants were asked about their use of 11 different COVID-19 information sources as well as their most trusted source of information. The selection of COVID-related knowledge and belief questions was based on past empirical literature and salient concerns at the time of survey implementation. Results The sample consisted of 11,242 participants. When combined, traditional media sources (television, radio, podcasts, or newspapers) were the largest sources of COVID-19 information (91.2%). Among those using mainstream media sources for COVID-19 information (n=7811, 69.5%), popular outlets included CNN (24.0%), Fox News (19.3%), and other local or national networks (35.2%). The largest individual information source was government websites (87.6%). They were also the most trusted source of information (43.3%), although the odds of trusting government websites were lower among males (adjusted odds ratio [AOR] 0.58, 95% CI 0.53-0.63) and those aged 40-59 years and ≥60 years compared to those aged 18-39 years (AOR 0.83, 95% CI 0.74-0.92; AOR 0.62, 95% CI 0.54-0.71). Participants used an average of 6.1 sources (SD 2.3). Participants who were male, aged 40-59 years or ≥60 years; not working, unemployed, or retired; or Republican were likely to use fewer sources while those with children and higher educational attainment were likely to use more sources. Participants surveyed in April were markedly less likely to use (AOR 0.41, 95% CI 0.35-0.46) and trust (AOR 0.51, 95% CI 0.47-0.56) government sources. The association between information source and COVID-19 knowledge was mixed, while many COVID-19 beliefs were significantly predicted by information source; similar trends were observed with reliance on different types of mainstream media outlets. Conclusions COVID-19 information source was significantly determined by participant sociodemographic characteristics and was also associated with both knowledge and beliefs about the pandemic. Study findings can help inform COVID-19 health communication campaigns and highlight the impact of using a variety of different and trusted information sources.
Disadvantages in preparing and publishing scientific papers caused by the dominance of the English language in science: The case of Colombian researchers in biological sciences

The success of a scientist depends on their production of scientific papers and the impact factor of the journal in which they publish. Because most major scientific journals are published in English, success is related to publishing in this language. Currently, 98% of publications in science are written in English, including researchers from English as a Foreign Language (EFL) countries. Colombia is among the countries with the lowest English proficiency in the world. Thus, understanding the disadvantages that Colombians face in publishing is crucial to reducing global inequality in science. This paper quantifies the disadvantages that result from the language hegemony in scientific publishing by examining the additional costs that communicating in English creates in the production of articles. It was identified that more than 90% of the scientific articles published by Colombian researchers are in English, and that publishing in a second language creates additional financial costs to Colombian doctoral students and results in problems with reading comprehension, writing ease and time, and anxiety. Rejection or revision of their articles because of the English grammar was reported by 43.5% of the doctoral students, and 33% elected not to attend international conferences and meetings due to the mandatory use of English in oral presentations. Finally, among the translation/editing services reviewed, the cost per article is between one-quarter and one-half of a doctoral monthly salary in Colombia. Of particular note, we identified a positive correlation between English proficiency and higher socioeconomic origin of the researcher. Overall, this study exhibits the negative consequences of hegemony of English that preserves the global gap in science. Although having a common language is important for science communication, generating multilinguistic alternatives would promote diversity while conserving a communication channel. Such an effort should come from different actors and should not fall solely on EFL researchers.
Peripheral blood circular RNA hsa_circ_0082688-hsa_circ_0008675 can be used as a candidate biomarker of systemic lupus erythematosus with renal involvement.

OBJECTIVES This research aimed to investigate the level of peripheral blood circular RNAs (circRNAs) from systemic lupus erythematosus (SLE) patients with renal involvement (SLE+RI) to identify novel biomarkers for SLE+RI screening. METHODS circRNAs expression in peripheral blood from 3 SLE+RI patients, 3 SLE patients without renal involvement (SLE-RI) and 3 healthy controls (HC) were performed by microarray. All upregulated expressed circRNAs coming from "circBase" between the three groups were determined by real time-quantitative polymerase chain reaction (qRT-PCR) in SLE+RI, SLE-RI, HC, neprhritis without SLE (NWS) and rheumatoid arthritis (RA) patients. The diagnostic value of these circRNAs for SLE+RI was evaluated by receiver operating characteristic (ROC) curve. A 15-day follow-up was evaluated in 7 newly diagnosed SLE+RI patients to investigate the level change of these circRNAs after treatment. RESULTS We confirmed that the level of hsa_circ_0082688, hsa_circ_0082689 and hsa_circ_0008675 were significantly elevated in SLE+RI patients with respect to the SLE-RI, RA, NWS patients and the HC. The level of hsa_circ_0082688, hsa_circ_0082689 and hsa_circ_0008675 were associated with C4, anti-dsDNA, anti-nucleosome. The level of hsa_circ_0008675 was associated with C3, and the level of hsa_circ_0082688 and hsa_circ_0008675 were associated with treatment. ROC curve analysis suggested that hsa_circ_0082688-hsa_circ_0008675 had significant value in the diagnosis of new-onset SLE+RI patients than the controls (new-onset SLE-RI patients, RA patients, NWS patients and HC) with an area under the curve of 0.925, sensitivity of 79.17% and specificity of 96.64%. CONCLUSIONS This study suggests that peripheral blood hsa_circ_0082688-hsa_circ_0008675 level in SLE+RI patients is upregulated and may also serve as a potential biomarker for SLE+RI patient diagnosis and treatment.
Single Mothers by Choice: Parenting and Child Adjustment in Middle Childhood

Findings are presented of the second phase of a longitudinal study of families created by single mothers by choice. Forty-four single heterosexual mothers were compared with 37 partnered heterosexual mothers, all with a donor-conceived child aged around 8–10 years. Standardized interview, observational, and questionnaire measures of maternal wellbeing, mother-child relationships and child adjustment were administered to mothers, children, and teachers. There were no differences in maternal mental health, the quality of mother-child relationships or children’s emotional and behavioral problems between family types. However, higher levels of parenting stress and higher levels of children’s prior adjustment difficulties were each associated with children’s adjustment difficulties in middle childhood irrespective of family type. The findings suggest that the presence of two parents—or of a male parent—is not essential for children to flourish, and add to the growing body of evidence that family structure is less influential in children’s adjustment than the quality of family relationships.
Targeted, Site-Specific, Delivery Vehicles of Therapeutics for COVID-19 Patients. Brief Review

Definitive pharmacological therapies for COVID-19 have yet to be identified. Several hundred trials are ongoing globally in the hope of a solution. However, nearly all treatments rely on systemic delivery but COVID-19 damages the lungs preferentially. The use of a targeted delivery approach is reviewed where engineered products are able to reach damaged lung tissue directly, which includes catheter-based and aerosol-based approaches. In this review we have outlined various target directed approaches which include microbubbles, extracellular vesicles including exosomes, adenosine nanoparticles, novel bio-objects, direct aerosol targeted pulmonary delivery and catheter-based drug delivery with reference to their relative effectiveness for the specific lesions. Currently several trials are ongoing to determine the effectiveness of such delivery systems alone and in conjunction with systemic therapies. Such approaches may prove to be very effective in the controlled and localized COVID-19 viral lesions in the lungs and potential sites. Moreover, localized delivery offered a safer delivery mode for such drugs which may have systemic adverse effects.