Miracle-dz/UniFAR-FTUs huggingface dataset:
From neutrino radiative transfer in core-collapse supernovae to fuzzy domain based coupling methods

This thesis consists in two parts: In the first part, we study the approximation of neutrino radiative transfer in core-collapse supernovae. In particular, we study the Isotropic Diffusion Source Approximation (IDSA). To do so, we first rederive the asymptotic limits used in this approximation using Hilbert and Chapman-Enskog expansions. We then show, using a model problem, that the coupling mechanism used in the IDSA can lead to unphysical solutions. We finally propose some corrections for the homogeneous sphere test case. In the second part, we introduce the framework of Fuzzy Domain Decomposition Methods (FDDMs). These methods are heterogeneous domain decomposition methods characterized by a time-dependent volumic adaptive coupling. We compare these methods with classical domain decomposition methods and quantify the approximation error for a simple class of 1D model using Matched Asymptotic Expansions (MAE). Finally, we formulate a time-dependent FDDM.
Effects of Logo Design toward Brand Personality Perception: A Study of Logo Elements in Real Estate Business

The topics of logo design perceptions have been examined among academic scholars recently. However, elements of logo as one aspect of logo designs were rarely studied and required to be investigated. This research aimed to measure the effects of logo elements comprising type font, graphic form, and color toward brand personality perceptions, as well as to explore the relationship between business stakeholders and brand personality. In addition, logo design meaning and brand personality traits including sincerity, excitement, security, and up to date were evaluated toward logo elements. Two hundred and sixty-five samples were selected using convenience sampling from employees and residents of Thai property developers. The mix method approach was employed for the data collecting through interviewing and questionnaire survey and analyzed by Chi-square tests. The findings reveal that logo design transfers all-inclusive meaning to viewers, encompassing name, graphic, and color interpretation. Besides, there is a connection between logo elements and perception of brand personality, but in order to obtain one salient dimension of brand personality, exhibiting the whole logo was suggested rather than individual element of logo. Furthermore, brand personality was considered vital among market sharing property industry which personality of sincerity was chiefly perceived when stakeholders appreciate a logo of their real estate brands.
An approximate analytical method for studying entry into planetary atmospheres

Report presenting a single, ordinary, nonlinear differential equation of second order that can be used for determining entry into an exponential planetary atmosphere. The reduced equation includes various terms, some of which represent the gravity force, the centrifugal acceleration, and the lift force. A number of solutions for lifting and nonlifting vehicles entering at various initial angles are obtained from the complete nonlinear equation.
LIVELIHOOD CHALLENGES AND COPING STRATEGIES OF AGRICULTURAL WORKERS DURING COVID-19 PANDEMIC

Bangladesh is one of the high-risk countries of the COVID-19 pandemic and its consequent losses. The main objectives of this research were to find out the livelihood challenges and coping strategies of agricultural workers during pandemic situation. This study was conducted targeting lower income group of people (temporary agricultural worker, casual agricultural workers). As the nature of the research was qualitative, the researcher used convenience sampling to select respondents because this is the most common non-probability sampling strategy where respondents were selected in an ad hoc fashion based on their accessibility. However, the researcher has taken 60 respondents as sample in analyzing data, descriptive statistics (frequency and percentage) of responses are estimated. Scores of livelihood challenges are the means of a 4-point Likert-type scale used. From this study find that most of the respondents did small business but they did not get any help or small loan from NGO. Most of the respondents drive rickshaw, auto as their off day. Due to closing of school, respondents’ children engage themselves to earning activities. Key words: Covid-19 pandemic, coping strategies, Livelihood challenges , Agricultural workers
NPY Gene Methylation in Circulating Tumor DNA as an Early Biomarker for Treatment Effect in Metastatic Colorectal Cancer

Simple Summary Despite several limitations, imaging is still the gold standard in evaluating the treatment effect in metastatic colorectal cancer, and the best response is often achieved several months after treatment start. The present study investigated methylated circulating tumor DNA (ctDNA) in the blood and found that a reduction in ctDNA after one treatment cycle was a better marker of progression-free survival than imaging. Furthermore, ctDNA increases in the blood before progression are visible on imaging, allowing for a change in treatment at an earlier time point. Methylated ctDNA is an early indicator of treatment benefit and a promising endpoint in clinical trials. Abstract Despite several limitations, the Response Evaluation Criteria in Solid Tumors version 1.1 (RECIST 1.1) are still the gold standard in response evaluation of metastatic colorectal cancer (mCRC). The aim of the present study was to investigate hypermethylated neuropeptide Y circulating tumor DNA (meth-NPY) as an early biomarker for treatment effect and monitoring in 70 mCRC patients receiving first-line treatment in the FOLFOXIRI-Toco trial. Meth-NPY was analyzed using droplet digital PCR, and the response rate was defined as the fraction of patients converting from a baseline detectable level to an undetectable level after the first treatment cycle (responders). A significant increase in meth-NPY was defined as a value with no overlap between the 95% CI of the current and preceding measurement. Progression-free survival (PFS) was significantly longer in meth-NPY responders compared to non-responders, 10.1 and 7.6 months, respectively (p = 0.02, HR = 0.43). Patients with response according to RECIST 1.1 had a PFS of 10.1 compared to 7.3 months for non-responders (p = 0.17, HR = 0.65). A significant increase in meth-NPY was found with a median of 49 days before radiological progression. In conclusion, early meth-NPY response proved superior to response according to RECIST 1.1 with respect to predicting improved PFS. Meth-NPY is an early indicator of progression, allowing treatment reorientation at an earlier timepoint.
Psychiatrist and trainee burnout: Commentary and recommendations on management

Objective To comment upon the evidence-base regarding psychiatrist and trainee burnout and provide recommendations on management. Conclusions Burnout has been conceptualised as a specific stress-related response, primarily related to work. There is a high prevalence of burnout amongst both trainees and psychiatrists internationally, with substantial consequences for personal and family wellbeing, organisational efficiency and patient care. We summarise the evidence on organisational and individual approaches to addressing burnout.
Real-World 20-Hz IBR Subsynchronous Oscillations: Signatures and Mechanism Analysis

This article provides analyses of subsynchronous oscillations associated with solar photovoltaics (PVs) observed in real world. All have oscillation frequencies at approximately 20 Hz in voltage and current magnitudes. On the other hand, in phase voltage and current, the oscillations show very different signatures. Through constructing simplified linear models and conducting sensitivity analysis, we are able to associate dynamic phenomena with the underlying mechanism and speculate the possible causes of the 20-Hz oscillations. The analysis results have all been validated via simulation results from electromagnetic transient (EMT) test beds constructed in MATLAB/Simscape.
The relationship between parents’ sleep quality and sleep hygiene and preschool children’ sleep habits

Objective The relationship between parents’ sleep quality and sleep hygiene and preschool children’s sleep habits was examined. Material and Methods The study population consisted of the parents of all preschool children at daycare centers located in Kermanshah Province. Through cluster sampling, 153 parents from 26 daycare centers were selected. In order to assess the quality of sleep and sleep health of parents, Pittsburg sleep quality index (PSQI) and sleep hygiene index (SHI) were used. As to the status of childrens sleep habits (CSH), the parents also completed child sleep habit questionnaire (CSHQ). Data analysis was performed in SPSS version 25. The non-parametric tests like U Mann-Whitney test, Kruskal-Wallis’s test, Spearman’s rho, and regression test were used. Results The mean score of CSHQ from the parents’ viewpoint was 56.34±7.96, which meant a relatively improper sleep habits in the children. The CSH was significantly and directly related to parents’ sleep quality and all of its subscales except two sub-scales (SSQ and HSE). In addition, CSH was directly and significantly related to the parents’ sleep hygiene and its three subscales. The results of multiple linear regression showed that the impact coeffcient of parents’ sleep quality (B=1.02), given the t-value, predicted changes in CSH with 0.99 confidence. Conclusion In general, the results showed that CSH was in a relatively bad state, while it had a direct relationship with parents’ sleep quality and hygiene. To improve CSH, it is possible to improve parents’ sleep quality through implementing proper programs and motivating parents to observe sleep hygiene.
Flexible OLED fabrication with ITO thin film on polymer substrate

This paper reports the synthesis of flexible indium tin oxide (ITO) films in a dual pulse magnetron sputtering (DPMS) system at low temperature (<100 °C) deposition condition. This study also presents experimental demonstration of the ITO films for their possible use in the fabrication of organic light emitting diode (OLED) device, and the device performance on the super polycarbonate substrates. The presented data reveals the feasibility of ITO films, with a very low sheet resistance of ∼30 Ω/□ and high transmittance of ∼88% at 550 nm, simply by the magnetron pulse mode operations with increasing pulse frequency from 0 to 50 kHz.
Can Corruption Facilitate Industrial Structure Upgrade in China? The Moderating Role of Government-Business Relationships

The literature on corruption is extensive. However, specific effects of corruption on industrial structure upgrade have received little attention in the context of China. Therefore, following the concept of organizational performance and social capital theory, a number of panel models are developed to explore how different institution domains (i.e., government’s willingness to reform, business ownership structure, and government-business collusion) moderate the effect size of corruption on upgrading the industrial structure in China. The results are generally robust after endogeneity corrections, and suggest that the effect size of corruption on the industrial structure upgrade is evidently moderated by willingness to reform and ownership structure, but government-business collusion does not appear to have a similar effect. These findings explain the variation in the corruption-performance link, and provide a novel perspective for policy makers and regulators to understand the evolutionary path of corruption within the process of economic transition in China. A local government must thoroughly understand the dynamics of an industrial structure upgrade and acquire competencies and knowledge about when the effect of corruption reaches its inflection point and how its downside can be alleviated by placing specific formal and informal institutional reforms.
Fetal Fibronectin as a Predictor of Preterm Delivery: A Nigerian Cohort Study

Background Fetal fibronectin is a useful biomarker in the diagnosis and management of preterm labour. Objectives To evaluate the relationship between cervical fetal fibronectin and preterm delivery and the association between cervical fetal fibronectin level and gestational age at delivery. Materials and Methods A prospective cohort study was performed in a tertiary hospital in Nigeria, involving equal number of pregnant women with (96) and without (96) preterm labour. Fetal fibronectin assay was done using solid-phase immunogold assay. The data were analysed using IBM SPSS version 24. Descriptive and inferential statistical analyses were done. The level of significance was p-value <0.05. Results Less than half (47.9%) of the women in the study group had preterm delivery while 13.09% of the women in the control group delivered preterm. Fetal fibronectin test had a sensitivity, specificity, positive predictive value and negative predictive value of 78%, 86.5%, 71.9%, and 89.0%, respectively, a positive likelihood ratio and negative likelihood ratio of 5.76(95% CI, 3.67 – 9.64) and 0.26(95% CI, 0.16 – 0.41), respectively. Conclusion The findings in our study value of fetal fibronectin in predicting preterm delivery. Its use will support less intervention for patients with negative results.
Extracellular Vesicles: A Novel Tool in Nanomedicine and Cancer Treatment

Simple Summary Extracellular vesicles (EVs) are plasma-membrane-encased particles with various biomolecules. Recent studies have demonstrated that EVs play a role in homeostasis and disease progression, and therefore may be important disease biomarkers. In cancer, EVs mediate inflammatory responses, oxidative stress, and contribute to altering the microenvironment. Additionally, EVs function as mediators in neurodegenerative diseases. Interestingly, EVs also promote stem cell differentiation, intercellular communication, and wound healing. These functions suggest that EVs can be utilized in medicine as therapeutic tools. Moreover, their endogenous nature and ability to carry intact biomolecules of different sizes to their target site due to their lipid bilayer makes them perfect drug transport systems that can be utilized in the treatment of many diseases, with higher efficacy and fewer side effects than other treatments as they can only target diseased cells and not healthy nearby cells, which occurs in conventional chemotherapy, for example. As such, their role in drug delivery has great potential. Abstract Extracellular vesicles are membrane-bound vesicles released by cells to mediate intercellular communication and homeostasis. Various external stimuli as well as inherent abnormalities result in alterations in the extracellular vesicle milieu. Changes to cells result in alterations in the content of the extracellular vesicle biogenesis, which may affect proximal and distal cells encountering these altered extracellular vesicles. Therefore, the examination of changes in the extracellular vesicle signature can be used to follow disease progression, reveal possible targets to improve therapy, as well as to serve as mediators of therapy. Furthermore, recent studies have developed methods to alter the cargo of extracellular vesicles to restore normal function or deliver therapeutic agents. This review will examine how extracellular vesicles from cancer cells differ from normal cells, how these altered extracellular vesicles can contribute to cancer progression, and how extracellular vesicles can be used as a therapeutic agent to target cancer cells and cancer-associated stroma. Here we present extracellular vesicles as a novel tool in nanomedicine.
Integration-Interconnection with a Scientific Approach on the Rational and Irrational Inequality of One Variable Module

Learning in madrasah tends to teach concepts and materials related to that science alone, without paying attention to other sciences. Thus, there is a need for innovation in learning that can link various fields of science, one of which is by applying integration-interconnection-oriented learning. The research aims to develop insights into integrated-interconnected mathematical learning modules with a scientific approach to rational and irrational materials of one variable is valid. The type of research used is research and development (R&D). This research was designed by following the steps of Richey and Klein's development, namely the PPE development model (Planning, Production, and Evaluation). The instrument used is a product validation assessment sheet given to two expert validators. The results showed that the integrated-interconnection-oriented mathematics learning module with a scientific approach that had been developed got an average product validity score of 0.82 with a high category. Thus, it can be concluded that this learning module has met the valid criteria.
Interaction of miR-155 with Human Serum Albumin: An Atomic Force Spectroscopy, Fluorescence, FRET, and Computational Modelling Evidence

This study investigated the interaction between Human Serum Albumin (HSA) and microRNA 155 (miR-155) through spectroscopic, nanoscopic and computational methods. Atomic force spectroscopy together with static and time-resolved fluorescence demonstrated the formation of an HSA/miR-155 complex characterized by a moderate affinity constant (KA in the order of 104 M−1). Förster Resonance Energy Transfer (FRET) experiments allowed us to measure a distance of (3.9 ± 0.2) nm between the lone HSA Trp214 and an acceptor dye bound to miR-155 within such a complex. This structural parameter, combined with computational docking and binding free energy calculations, led us to identify two possible models for the structure of the complex, both characterized by a topography in which miR-155 is located within two positively charged pockets of HSA. These results align with the interaction found for HSA and miR-4749, reinforcing the thesis that native HSA is a suitable miRNA carrier under physiological conditions for delivering to appropriate targets.
Internal Metabolic Changes in Cut Flowers1

The study of the postharvest physiology of cut flowers is still in its infancy, but showing growth. In 1936, Laurie (20) made the following statement in his presidential address to the members of the American Society for Horticultural Science: “Although many attempts have been made to study the keeping quality of cut flowers, little definite and specific information is yet available. The workers at Illinois, Iowa, Cornell, Boyce-Thompson and Ohio are largely responsible for these studies. The use of various chemicals as well as carbon dioxide has been tried with some degree of success in specific cases … At present, studies in Ohio are being made with the correlations between refrigeration and humidity as well as the factors which reduce respiration rate and rapid maturity” Some 36 years later, we find an increasing interest in the postharvest physiology and biochemistry of cut flower senescence. However, much basic information and applied work is needed to aid the expanding flower industry of this country. This paper will attempt to review in detail the research literature to date on the internal metabolic changes in cut flowers.
Gamified environmental multi-criteria decision analysis: information on objectives and range insensitivity bias

Multi-criteria decision analysis (MCDA) is well suited to address complex public policy problems but could beneﬁt from new tools to involve many laypeople. Online information on specialized topics could be more engaging by including game elements. This paper reports an experiment that assessed a gamiﬁed interface to (1) inform laypeople about the objectives to consider in wastewater management decisions, (2) assist them in constructing range-based preferences, and (3) provide a positive experience. We measured the eﬀects with (1) a knowledge pre- and posttest, (2) the elicited weights and a range sensitivity index, and (3) an experience questionnaire based on self-determination theory. Answers from 174 participants indicated that participants learnt about the objectives and constructed preferences in both the gamiﬁed and control treatments. How-ever, in neither were weights suﬃciently adjusted. Our gamiﬁcation making the ranges salient did not help overcome this bias. Both treatments were experienced as neutral to positive, the gamiﬁed being more entertaining. We discuss implications: if gamiﬁcation of tools for participatory decision-making is to be promoted, it requires further research. Range insensitivity remains an unresolved bias in MCDA.
Examining complementary relationships among climate change adaptation practices of rice producers in Chitwan, Nepal

ABSTRACT This study examines how the complementary relationships among multiple climate change adaptation strategies (improved varieties, irrigation practices and direct-seeded rice, referred to as ‘DSR’) are influenced by access to Extension services, training related to farming practices and weather-related information (referred to as ‘institutional factors’). This study hypothesizes the influence of institutional factors and the resulting effects on their joint adoption using survey data collected from 359 rice producers in Chitwan district of Nepal in 2019. The results indicate: (1) adoption of all the three climate change adaptation practices are complementary to each other; (2) all three institutional factors enhance the likelihood of the adoption of variety, access to Extension and training enhances the likelihood of the adoption of improved irrigation, and information enhances the likelihood of the adoption of DSR and (3) access to Extension and training enhance the complementarities among all three pairs of adaptation practices (variety and irrigation; variety and DSR and irrigation and DSR), while information enhances the complementarity between variety and DSR only. The impact of complementary relationships among multiple climate change adaptation strategies influenced by the institutional factors is particularly valuable for policy makers and government agencies to allocate and prioritize resources.
Prevalence of Chronic Rhinosinusitis with Nasal Polyps in Catalonia (Spain): a retrospective, large-scale population-based study.

BACKGROUND Studies on the prevalence of chronic rhinosinusitis (CRS) with nasal polyps (NP) in general-based populations are scarce in Europe and worldwide. We performed a retrospective population-based observational cohort study of 30,189 adult patients diagnosed with NP in Catalonia (Spain). METHODOLOGY Adult individuals (≥18 years old) with a diagnosis of NP established by medical records at different health care levels (primary, hospital, and emergency) from the Catalan Health System (CHS) were included. Socio-demographic characteristics, prevalence, overall and by age and gender, disease severity, multi-morbidities, and biomarkers of type-2 inflammation were evaluated, together with appropriate medical treatment (AMT) and Endoscopic Sinus Surgery (ESS). RESULTS In general population and severity sub-populations, the overall diagnosed NP prevalence was 0.49% and higher for males than females (0.60% vs 0.39%, p less than 0.0016). The prevalence for the severe NP population was 0.12%. The NP prevalence increased with age, the highest being at ≥ 60 years old for both gender and severity groups. Asthma (40.1%), acute rhinosinusitis (41.1%), and allergic rhinitis (32.1%) were among the most frequent comorbid respiratory diseases. ESS was performed in 15.4% of NP patients. Type 2 inflammation was present in 83.8% of the NP population and was more frequent in severe than non-severe (87.1% vs 82.7%, p less than 0.0001) patients and in those with respiratory multi-morbidities (91%). CONCLUSIONS This is the first large-scale population-based NP epidemiology study conducted in Spain, including severity based on undergoing medical and surgical treatment and type 2 inflammation. Although the prevalence data are lower than in previous European studies, the large NP cohort studied represents an essential strength of the results.