Miracle-dz/UniFAR-FTUs huggingface dataset:
Divergences between mHealth drug interaction checkers: a highlight on HIV hospitalized patients therapy

Introduction: Mobile health (mHealth) apps have been involved in contemporary clinical practice in potential drugdrug interactions (pDDIs) research. However, available pDDIs information may differ between apps, which could impact the success of patient's drug therapy. This study analyzed the performance of the mHealth apps in a context of pharmacotherapy prescribed to HIV/AIDS hospitalized patients. Methods: Cross-sectional study was conducted in a referral hospital for infectious diseases, central Brazil. Drug prescriptions were selected randomly by census. A pDDIs prevalence, severity classification as well the agreement of information and performance of different mHealth checkers were analyzed. Free access mHealth apps were selected: Drugs®, EpocratesRx®, and Micromedex® (considered as reference app). Analysis of sensitivity, specificity, positive or negative predictive values (PPV or NPV) was conducted. Results: The majority of 33 HIV/AIDS hospitalized patients was males, young adults, with opportunistic infections despite of a recent HIV diagnosis. 373 drugs were prescribed with 461 pDDIs identified by mHealth checkers. The pDDIs prevalence was 13.9% (12.4-15.6), 22.2% (20.1-24.5) and 24.8% (22.9-26.8) in Micromedex®, EpocratesRx® and Drugs®, respectively. Micromedex® classified most of pDDIs (71.2%) as major, while Drugs® (67.6%) and EpocratesRx® (84.8%) classified most of them as minor. In comparison with Micromedex®, Drugs® or EpocratesRx® showed none (K<0.00) or little (K=0.11) agreement in identification of pDDIs, respectively. Performance analyzes showed that Drugs® presented greater sensitivity (75.4%), however, the results of specificity, PPV, NPV, and accuracy were similar by both apps when compared to the reference. Conclusion: The mHealth drug interaction checkers presented important divergences in the results of identification, classification of severity and prevalence rate of pDDIs.
Serum Asprosin Levels in Women with Polycystic Ovary Syndrome in Duhok City, Kurdistan Region of Iraq

Asprosin is a novel peptide hormone produced and secreted by white adipose tissues. Asprosin associated with insulin resistance and promotes hepatic glucose production. Previous studies showed that serum asprosin was raised in the general population with polycystic ovary syndrome (PCOS). However, there were studies supporting the opposite. Also, there were studies that showed the highest levels of asprosin was due to insulin resistance, as well as in type 2 diabetes patients. PCOS is one of the metabolic disorders related to insulin resistance. Therefore, the current study aims to evaluate the levels of asprosin in the blood serum of women with PCOS compared to the healthy women who resident in Duhok in the Kurdistan Region of Iraq. A cross-sectional study was conducted from 20th of June, 2020 to 11th of January, 2021 at Obstetrics and Gynecology Hospital and Mazi medical clinics. Serum asprosin level was determined in 75 women with PCOS (18-44 years) and 96 healthy women. SPSS software was utilized for analyzing the study data. The (means ± SD) of demographic parameters (body mass index (BMI) and waist circumference (WC)) in women with PCOS were significantly highest in comparison to healthy women. The biochemical parameters (serum asprosin, fasting blood sugar (FBS), fasting insulin (FI), total cholesterol (TC), and triglyceride (TG)) in women with PCOS also were remarkably higher compared to healthy women with the exception of high-density lipoprotein- cholesterol (HDL-C). The current data show that serum asprosin variance significantly between WC, BMI, FBS, FI, TC, TG and HDL-C. The study confirms that serum asprosin in women with PCOS was higher than in the healthy women. In addition in women with PCOS it was found that serum asprosin was positively correlated with BMI, WC, FBS, FI, HOMA-IR, TC and TG (P<0.05). Except, HDL-C was negatively correlated with serum asprosin (P<0.01).
Students' Perceptions of Online Learning and Teaching during COVID-19 pandemic: An Empirical Study in Selected University in Sri Lanka

The dramatic transition to online pedagogy in education, as a consequence of COVID19 has shownseveral inequalities and challenges and advantages in education. The epidemic of COVID-19 profoundly changed the global higher education system in 2020, and the crisis has accelerated innovation in the education sector. Anyhow, whatever the situation, high academic standards are required for a university to produce high-quality teaching outputs and graduates, and it should ensure continuously. With this intention, this study conducted to assess the efficacy of online teaching and learning during the COVID-19 pandemic, focusing on the perceptions of undergraduate students from the Selected university.A validated online questionnaire is used among the 171 students from the selected university. The primary goal of this paper is to analyse how the education system adapts to online teaching and learning, identify the preferred mode of study by the students in between face to face interaction and online learning, and identify the advantages and challenges faced by the students in online learning. The paper also aims to make recommendations for improving online teaching and learning through the use of online. The study's findings show that, even though the students are satisfied with the existing online teaching and learning in selected university, they prefer face to face learning than online learning. The study strongly recommends that improving the quality of the online education system and striving to solve students' issues in terms of online learning is required to maintain the standard in education. The study's findings shed light on government and non-government educational institutions, academics, and policymakers to enhance online education and maintain the education standard.
Foreign and Bilingual Language Education in the UK and Spain: A Study of Similarities and Differences

Language learning, as a means to promote intercultural awareness and communication as well as to help citizens prosper professionally, is one of today’s main goals of educational systems around the world. In Europe, several guidelines have been published, and significant efforts have been devoted to encouraging the development of the quality of foreign and bilingual language education to improve citizens’ communicative skills. Although there were attempts to foster foreign language proficiency in some parts of the United Kingdom between the 1990s and the early 2000s, the country has not traditionally considered languages among its educational priorities. Nonetheless, Brexit seems to have increased the need to learn languages in the country. In some other European countries, however, Content and Language Integrated Learning (CLIL), an additive bilingual approach, has been implemented since the early 2000. Considering that the nations in the United Kingdom and the regions in Spain have the freedom to organise educational affairs, an analysis of the provision of foreign and bilingual language education in the United Kingdom and Spain appears relevant. This paper presents the results of a systematic review of 2012-2020 literature in the field of foreign and bilingual language education in both contexts. The differences that exist within the United Kingdom concerning foreign language teaching are discussed, and information in relation to the provision of CLIL in some Spanish regions is also examined. The findings show that foreign language teaching is provided across the United Kingdom, whereas bilingual education is offered in the form of Welsh-, Irish-, and Gaelic-medium education mainly, although CLIL is also implemented in England.
A Study on the Increase of Perceivable Information in the Saccade with High Speed Line Display

SUMMARY A line display that utilizes saccade has been proposed. When an observer moves his or her eyes on a one-dimensional fixed line display, two-dimensional information is perceived on the retina. In this paper, a high speed flashing line display was developed using a CPLD and PIC microcontroller. The flashing period was reduced to 20 μs, which was less than half that of our previous system. The relationship between the flashing frequency and the optimum distance that can be perceived with the least distortion was clarified. The results show that the higher the flashing frequency is, the more information can be perceived from a farther position. Calculated values, which were based on the relationship between the flashing period and the light source size, were almost identical with measured values at the flashing frequencies from 3.3 kHz to 10 kHz. Due to short flashing period, the developed line display not only was visible at distance of 15 m or more, which is suitable for outdoor use, but also realized 16 gray levels.
Inactivation Kinetics and Thermodynamics Parameters of Polyphenol Oxidase and Peroxidase Activities in an Extract from of Violet Eggplant (Solanum melongena L.)

Enzymatic browning is associated with the action of polyphenol oxidases (PPO) and peroxidases (POD). The products of these enzymes cause undesirable changes of color and flavor of processed eggplant products. The present study aimed to evaluate kinetic properties and thermodynamics parameters of PPO and POD activities for controlling this undesirable process in extract from of violet eggplant. The effect of heat treatment on polyphenol oxidase and peroxidase activities in violet eggplant were studied over a range of 30 to 80 °C. T1/2-values of enzymatic activities are between 6.15 ± 0.03 and 13,27 ± 0,04 min at 80 °C, they decreased with increasing temperature, indicating a difference thermostability of each enzyme. Dand k-values decreased Original Research Article Yapi et al.; EJNFS, 13(3): 83-92, 2021; Article no.EJNFS. 69780 84 and increased, respectively, with increasing temperature, indicating faster of these enzymes inactivation at higher temperatures. Results suggested that polyphenol oxydase and peroxidase were relatively thermostable enzymes with a Z-value which from 50.25 and from 88.33 °C and Ea of 41.21 and of 27.78 kJmol -1 . Thermodynamic parameters were also calculated. The Gibbs free energy ΔG values range from 43.24 ± 0,03 to 91.45 ± 0,01 kJ/mol. These kinetic data can be used to predict prevention of browning in the violet eggplant (Solanum melongena L.) by thermal inactivation of enzymes.
Heterosis and Combining Ability of some Colored Rice Genotypes for Yield Characteristics and Grain Micronutrient Content Using Line X Tester Analysis

Eight exotic colored rice lines and four testers were crossed in line x tester. The resulted 32 F1 hybrids along with their parents were evaluated in a randomized complete block design (RCBD) with three replications at the Experimental Farm of Rice Research Department, Sakha Agricultural Research Station, Kafr El-Sheikh, Egypt during2019 and 2020 growing season, to assess mean performance, general (GCA) and specific (SCA) combining ability as well as identify type of gene action controlling the inheritance of the studied traits. The non-additive gene effects had an important role in the inheritance of all the studied traits more than the additive gene effects. The parental lines Dullar, Black Rice and IRBLKM-TS-[CO] were identified as a good combiners for earliness and KWANG CHANG Ai, Black Rice and Sakha 101 for shortness. Whereas, parental lines: Dullar, Red Rice, IRBLKM-TS-[CO], IRBLTACT and Sakha 108 were the best general combiners for grain yield and its components. The hybrid combinations Dullar x Giza 178, Red Rice x Giza 178, B40 x Giza 178, KWANG CHANG Ai x Sakha 108, Dullar x Giza 177 and IRBLTA-CT2 x Sakha 108 had the best SCA effects for grain yield as well as one or more of its components. Moreover, the hybrids Red Rice x Giza 178, IR71567-108-1-2 x Giza177 and B40 x Sakha108 recorded the highest value in Fe and Zn concentrations in grains. These hybrids could be used for improving grain yield and micronutrient content particularly Fe and Zn in rice breeding programs.
Textile electrodes for bioimpedance measuring

This article deals with the development and comparison of eight different electrodes made out of a cotton fabric substrate, a silver coated yarn and partly conductive finishes, i.e. a PEDOT:PSS Orgacon ICP 1050 dip-coating and a Powersil coating. The purpose is the application especially in the medical field of angiopathy like for bioimpedance measurements during compression therapies. To be able to compare the suitability of the electrodes, various tests have been performed of the coating abrasion resistance, the stability of electrical resistance values, as well as resistance and bioimpedance measurements. Significant differences between the electrodes regarding their resilience and resistance that are visualized in a value-added analysis were found, with one hand-embroidered, one machine-sewn and one commercial electrode showing optimum properties.
Consensus molecular subtype differences linking colon adenocarcinoma and obesity revealed by a cohort transcriptomic analysis

Background Colorectal cancer (CRC) is the third-leading cause of cancer-related deaths in the United States and worldwide. Obesity, a worldwide public health concern, is a known risk factor for cancer including CRC. However, the mechanisms underlying the link between CRC and obesity have yet to be fully elucidated in part because of the molecular heterogeneity of CRC. We hypothesized that obesity modulates CRC in a consensus molecular subtype (CMS)-dependent manner. Methods RNA-seq data and associated tumor and patient characteristics including body weight and height data for 232 patients were obtained from The Cancer Genomic Atlas Colon Adenocarcinoma (TCGA-COAD) database. Tumor samples were classified into the four CMSs with the CMScaller R package; Body mass index (BMI) was calculated and categorized as normal, overweight, and obese. Results We observed a significant difference in CMS categorization between BMI categories. Differentially expressed genes (DEGs) between obese and overweight samples and normal samples differed across the CMSs, and associated prognostic analyses indicated that the DEGs had differing effects on survival. Using Gene Set Enrichment Analysis, we found differences in Hallmark gene set enrichment between obese and overweight samples and normal samples across the CMSs. We constructed Protein-Protein Interaction networks and observed differences in obesity-regulated hub genes for each CMS. Finally, we analyzed and found differences in predicted drug sensitivity between obese and overweight samples and normal samples across the CMSs. Conclusions Thus, we conclude that obesity has CMS-specific effects on the CRC tumor transcriptome.
DETERMINANTS OF HOUSEHOLD’S POVERTY AMONG CROP FARMERS IN KADUNA STATE, NIGERIA

This study examined the households’ poverty status among crop farmers in Kaduna State. Multi-stage sampling procedure was used to select 242 farmers for this study. Data were collected through using structured questionnaire with the help of trained enumerators. Descriptive and inferential statistics such as tobit regression and Foster, Greer and Thorbecke (FGT) model was employed in this study. The results showed that the mean age of the respondents was 45 years and were married, mean household size of the farmers was 11 persons, and about (80.6%) had formal education. The poverty situation of the farmers revealed that 51% were poor and the strategies adopted by the farmers to combat poverty were mostly through diversification into commercial farming, increased personal savings and involvement in non-farming activities. Tobit regression analysis revealed that age, household and income negatively influences the poverty status of the farmers, statistically significant at 1%, this implied that, poverty is concentrated among households in the study area. Major constraints encountered by the crop farmers, include high cost of inputs, inadequate credit facilities and inadequate market linkages. In conclusion, poverty incidence had a negative and significant effect on rural crop farmers. It was recommended that farmers should form cooperative societies to access micro loan; farmer should be linked to the urban market through extension agent and media to attract good value for their crops. Government and Non-Governmental Organizations (NGOs) should make farm inputs readily available at a
Features of small holder goat farming from Chitwan district of Bagmati province in Nepal

Received: 01 April 2021 Revised received: 12 May 2021 Accepted: 15 June 2021 An assessment was done to analyze the status of small scale goat production system in Chitwan, Nepal. A semi-structured questionnaire having both open ended and close ended questions were interviewed to 147 farmers (69 males, 78 females). The average goat holding was 5.48±0.15 head with female: male ratio of 6: 5. Mainly women folks in the household were involved in husbandry of the raised goats. In this research, we realized that goats were a valuable commodity for the community in the survey area. Grazing in public forest, fallow lands, tree leaves, shrubs and bushes were the main sources of feed for goats throughout the year. When inquired about vaccination, 92.51% of the farmers did not vaccinate their goats and were not aware about its importance. The high index obtained was for health care constraints, followed by feeding constraints, breeding constraints, miscellaneous and marketing constraints. The findings of this survey are not very encouraging as even from one of the developed parts of the country, small scale farmers raising goats seem to be struggling both in terms of technical and logistic inputs. There is need of awareness on improved care and management practices of goat.
The Spirituality of Rural Muslim Communities through Jam’iyyah Nahdlatul Ulama Routine Activities

The purpose of this research is to describe the spirituality of rural Muslim communities through the routine activities of Jam’iyyah Nahdlatul Ulama from Ngemplak Simongan NU Sub-District. This research is a field research (qualitative) which elaborated phenomenology approach that uses observation, interviews, and documentation as a method of collecting data, which is also equipped with a library research. The research shows that the spirituality of the Muslim community and the Jam’iyyah NU, Ngemplak Simongan Village is also still very much carrying the spirit of local wisdom based on Islamic values to this day. They also still carry out Javanese religious rituals, such as routine recitation activities, tahlil, yasinan, diba’, istighāstah, manāqib, and ziyārah Walisongo, because they believe that basically all of these rituals are part of Islamic teachings and originated from Islamic teachings. Jam’iyyah NU Ngemplak Simongan can also be categorized as “Moderate Muslim” because they still uphold the values of locality in religion. Based on the results, it shows that Jam’iyyah NU, Ngemplak can be used as a miniature of NU moderation in suburban villages of Semarang City. Jam’iyyah NU, Ngemplak, which in fact is a sub-district in the metropolitan city of Semarang, Central Java, they often and routinely carry out Ahlussunnah wal Jama’ah An-Nahdliyyah (Aswaja NU) activities to maintain the spiritual spirit of rural Muslim communities.
Effect of Acute Exposure of Cigarette Smoke on Endometrium Thickness and Number of Ovarian Follicles in Rats

Background: Cigarrete smoke has been ascociated with many health-related problems especially in long time use. One of many health problems that are affected is the reproductive system that give negative impact in fertility. However, there are limited studies about this in acute exposure of cigarette smoke. Objective: The aim of this study is to investigate the effect of acute exposure of cigarette smoke on endometrial thickness and number of ovarian follicles in rats. Methods: Thirty adult female rats were randomly divided into 3 groups: P0, P1 and P2. The P1 and P2 groups were exposed to cigarette smoke for 15 days with dose of 2 and 4 cigarettes daily, respectively. Vaginal swab was done twice, before and after the last treatment, to determine the proestrus phase of the animals. Histological slide of uterus and ovarium using Haematoxylin Eosin staining were observed under light microscop. Number of ovarian follicles were measured, and the thickness of endometrium was meassured using CellSens software version 2.3 (Olympus Life Science). Statistical analysis of data was performed using MANOVA in SPSS software version 23 for Windows. Results: There were no significant differences in both endometrial thickness and number of ovarian follicles between 3 groups (p>0.05). However, we found that there were a downward trend of some variables (endometrial thickness, number of primary follicles, de Graff follicles, and corpus luteum) from P0 to P2. Conclusion: We concluded that acute exposure of cigarette smoke not yet influenced the female reproductive organ, based on histological appearance of endemotrium and ovarium.
Characteristics of medium-low rank coal blending on performance and efficiency steam power plant

Blending medium rank coal (MRC) with low-rank coal (LRC) is carried out to meet the caloric content which follows the boiler specifications. Negative effects of blending with LRC are environmental, specific fuel consumption (SFC), and efficiency issues. The purpose of this research is the optimum blending composition of LRC and MRC coal, which can be used by power plants. The research methodology used is to simulate coal blending with MRC percentage in the MRC-LRC from 0, 20%, 40%, 50%, 60%, 80%, and 100%. The type of coal used is categorized in MRC1, MRC2, LRC1, LRC2, LRC3. The combination used is MRC1-LRC1, MRC1-LRC2, and MRC2-LRC3. From the analysis obtained, if the MRC percentage in MRC-LRC blending increases, losses will decrease mass flow will decrease, SFC will decrease, and boiler efficiency will increase. Blending MRC2-LRC3 has the lowest losses, low mass flow with an average of 298.78 ton/h, low SFC with an average of 0.466 kg/kWh, and boiler efficiency between 84.85% to 85.71 %. Blending MRC2-LRC3 is most recommended for use in combustion plant with a minimum MRC2 percentage of 50%.
Identification of potential quorum quenching compounds in Brassica oleracea var. capitata against MDR Pseudomonas aeruginosa and Escherichia coli clinical isolates

Over the last decades, the development of microbial resistance has become an alarming situation. This has urged the search for new antimicrobial strategies. In this context, two Brassicaceae edible plants; Brassica oleracea var. capitata (cabbage) and Brassica rapa subsp. rapa (Turnip) were assessed for their antimicrobial activity against P. aeruginosa and E. coli clinical isolates. Antibiogram analysis was done according to the CLSI 2019 guidelines and proved that both P. aeruginosa and E. coli clinical isolates were multidrug-resistant. A green extraction methodology – assisted by microwave and ultrasoundwas used to prepare the aqueous extracts. Determination of minimum inhibitory concentration (MIC) of the extracts was also carried out according to the CLSI guidelines. At sub-MIC concentration, cabbage extract showed promising results in the inhibition of quorum sensing mediated virulence determinants of P. aeruginosa. The highest reduction was observed in pyocyanin and rhamnolipid production. Chemical profiling via UPLC-ESI-MS analysis of cabbage extract revealed the presence of different glucosinolates together with iberin and sulforaphane. The in silico docking study was conducted and revealed the ability of sulforaphane and iberin to bind to the LasR regulator responsible for quorum sensing in P. aeruginosa. These compounds thus represent potential candidates that can be developed into novel antimicrobial infection control tools.