Miracle-dz/UniFAR-FTUs huggingface dataset:
Classification of proteins using sequential and structural features

Classification of proteins is an important process in many areas of bioinformatics research. In this thesis, we devised three different strategies to classify proteins with high accuracy that may have implications for function and attribute annotation. First, protein families were classified into different functional subtypes using a classification-via-clustering approach by using relative complexity measure with reduced amino acid alphabets (RAAA). The devised procedure does not require multiple alignment of sequences and produce high classification accuracies. Second, different fixed-length motif and RAAA combinations were used as features to represent proteins from different thermostability classes. A T-test based dimensionality reduction scheme was applied to reduce the number of features and those features were used to develop support vector machine classifiers. The devised procedure produced better results with less number of features than purely using native protein alphabet. Third, a non-homologous protein structure dataset containing hyperthermophilic, thermophilic, and mesophilic proteins was assembled de novo. Comprehensive statistical analyses of the dataset were carried out to highlight novel features correlated with increased thermostability and machine learning approaches were used to discriminate the proteins. For the first time, our results strongly indicate that combined sequential and structural features are better predictors of protein thermostability than purely sequential or structural features. Furthermore, the discrimination capability of machine learning models strongly depends on RAAAs.
The Life of Primates

Preface Chapter 1: Introduction to the Nonhuman Primates Chapter 2: Primate Classification Chapter 3: Primate Biogeography Chapter 4: The Primate Body Chapter 5: Primate Evolution Chapter 6: Primate Ecology Chapter 7: Primate Social Organization Chapter 8: Primate Social Relationships Chapter 9: Primate Communication Chapter 10: The Primate Brain and Complex Behavior Chapter 11: Primate Conservation Appendix A Metric-Imperial Conversions Appendix B Comparative Primate Skeletons Appendix C List of all Extant Species Appendix D List of all Extinct Species Glossary Bibliography
Proteins and Amino Acid Composition of Korea Ginseng Classified by Years

For the systematic investigation of biochemical characteristics of Korean ginseng protein by years, protein fractions were analyzed by the techniques of polyacrylamide gel electrophoresis, sodium dodecyl sulfate polyacrylamide gel electrophoresis (SDS-PAGE) and gel filtration, while the amino acid composition was studied by amino acid autoanalyzer. Results of polyacrylamide gel electrophoresis and SDS-PAGE showed a few difference in pattern and number of bands depending on the age of the root. However, the number of bands obtained from polyacrylamide gel electrophoresis and SDS-PAGE was 8 and 7 to 11, respectively. When water extracted proteins were fractionated by Sephadex G-200, the main peak among 2 peaks was collected and lyophillized. Its mol. wt. was extimated to be 43,000 by the SDS-PAGE method. In amino acid composition of water extracted protein and main fraction of gel filtration, arginine content was the highest, 47.17% in water extracted protein and 57.36% in main fraction followed by glutamic acid and asparatic acid. On the contrary, cystine and methionine contents were very low in both cases.
Isolation, serotyping and antibiogram of Pasteurella from pigs of North East India

Altogether 309 samples from 187 pigs apparently healthy, 77 slaughtered for pork, 25 dead and 22 ailing pigs with gross lesions and clinical symptoms suggestive of pasteurellosis were screened for isolation of Pasteurella. Fifty (26.73%) animals were positive for Pasteurella species, form dead pigs (52%). Strains (63%, 20.38%) of Pasteurella were isolatted consisting 52 (82.54%) Pasteurella multocida and 11 (17.46%) Manneimia (Pasteurella) haemolytica. Recovery of Pasteurella multocida was the highest form lung followed by nasal swabs while M. (Pasteurclla) haemolytica could be recovered only from lung followed by nasal swabs. Among the 52 Pasteurella multocida isolated isolates 26 (50%) belonged to serotype A, 10 (19.23%) to serotype B while 16 (30.76%) were untypable. All the 11 isnlales of M. (Pasteurella} haemolytiea strains were untypable. Strains of Pasteurella mliltocida were highly sensitivity to cephalexin (100%) followed by nortloxacin (96.15%) and gentamicin (88.46%) and were least sensitive to lincomycin (7.69%). Similar type of sensitivity towards cephalexin and nortloxacin (100%) was also observed among the strains of M. (Pasteurella) haemolytica.
Immigration Policy and Macroeconomic Performance in France

This paper quantitatively assesses the interaction between permanent immigration into France and France's macroeconomic performance as seen through its GDP per capita and its unemployment rate. It takes advantage of a new database where immigration is measured by the flow of newly-issued long-term residence permits, categorized by both the nationality of the immigrant and the reason of permit issuance. Using a VAR model estimation of monthly data over the period 1994-2008, we find that immigration flow significantly responds to France's macroeconomic performance: positively to the country's GDP per capita and negatively to its unemployment rate. At the same time, we find that immigration itself increases France's GDP per capita, particularly in the case of family immigration. This family immigration also reduces the country's unemployment rate, especially when the families come from developing countries.
Study of Sleep Patterns and Other Sleep Related Factors among Residents of Jaipur City

Adequate amount and good quality of sleep affects both the mental and physical health. Any disturbance in this vital physiological process in turns affect the quality of our work. Objectives: The current study aimed to determine the sleep patterns and other sleep related factors. The current cross-sectional study was conducted on 1000 healthy and randomly selected participants from Jaipur city. Self-recalling and personal interview with the participant was employed for data collection. Data was extracted using Microsoft Excel (2010) spreadsheets. The mean age of the participants was 36.12 + 8.45 years. Results showed maximum sleep latency of greater than one hour in business class participants (53.5%), followed by students. Profession wise distribution of sleep revealed that 87.7% of the house wives slept for 7-8 hr while the duration of sleep was less than 5 hours among 96.4% business professionals. 72.7% housewives described their sleep quality to be perfect in contrast to 12.6% students. Sleep talking was the most commonly encountered type of parasomnia affecting 92% students, 73% service class, 65% business people and 81% housewives. The results of the current study showed a high prevalence of sleep problems among the business professionals followed by the students. Timely identification and appropriate treatment of sleep disorders in these groups may improve life quality in them.
Scheme of a Derivation of Collapse from Quantum Dynamics II

Is wave function collapse a prediction of the Schrodinger equation? This unusual problem is explored in an enlarged framework of interpretation, where quantum dynamics is considered exact and its interpretation is extended to include local entanglement of two systems, including a macroscopic one. This property of local entanglement, which results directly from the Schrodinger equation but is unrelated with observables, is measured by local probabilities, fundamentally distinct from quantum probabilities and evolving nonlinearly. When applied to a macroscopic system and the fluctuations in its environment, local entanglement can also inject a formerly ignored species of incoherence into the quantum state of this system,. When applied to a quantum measurement, the conjunction of these two effects suggests a self-consistent mechanism of collapse, which would directly derive from the Schrodinger equation. (This work develops and improves significantly a previously circulated version with the same title [23])
The Case for Universal Banking as a Component of Islamic Banking

Universal banking is one of the main components of Islamic banking. Islamic banks provide finance to enterprises through either sharing directly in the net results of their activities or financing their purchases of assets, goods and services on credit. We can therefore expect Islamic banks to hold equity in corporations and sit on their boards of directors. This paper aims to put forward the case of universal banking as a part of Islamic banking. A large amount of literature is surveyed that comes from banking theory, macroeconomic and monetary theory, as well as empirical studies about banking practices. The conclusion is that universal banking on its own is a sound practice that can offer developing countries special advantages. Such a conclusion is rather important because many of the Islamic countries where believers in Islamic banking reside are developing. It would therefore be helpful to see that Islamic banking as it contains universal banking would give a helping hand in the process of development that would not be easily obtained from conventional banking.
Land-Use/Land-Cover Change Analysis and Urban Growth Modelling in the Greater Accra Metropolitan Area (GAMA), Ghana

A rapid increase in the world’s population over the last century has triggered the transformation of the earth surface, especially in urban areas, where more than half of the global population live. Ghana is no exception and a high population growth rate, coupled with economic development over the last three decades, has transformed the Greater Accra region into a hotspot for massive urban growth. The urban extent of the region has expanded extensively, mainly at the expense of the vegetative cover in the region. Although urbanization presents several opportunities, the environmental and social problems cannot be underestimated. Therefore, the need to estimate the rate and extent of land use/land cover changes in the region and the main drivers of these changes is imperative. Geographic Information Systems (GIS) and remote sensing techniques provide effective tools in studying and monitoring land-use/land-cover change over space and time. A post classification change detection of multiple Landsat images was conducted to map and analyse the extent and rate of land use/land cover change in the region between 1991 and 2015. Subsequently, the urban extent of the region was forecasted for the year 2025 using the Markov Chain and the Multi-Layer Perceptron neural network, together with drivers representing proximity, biophysical, and socio-economic variables. The results from the research revealed that built-up areas increased by 277% over the 24-year study period. However, forest areas experienced massive reduction, diminishing from 34% in 1991 to 6.5% in 2015. The 2025 projected land use map revealed that the urban extent will massively increase to cover 70% of the study area, as compared to 44% in 2015. The urban extent is also anticipated to spill into the adjoining districts mainly on the western and eastern sides of the region. The success of this research in generating a future land-use map for 2025, together with the other significant findings, demonstrates the usefulness of spatial models as tools for sustainable city planning and environmental management, especially for urban planners in developing countries.
Non-Secretors of ABH Antigens Are Susceptible to Falciparum Malaria

ABH secretor status has been associated with a number of infectious diseases. This study was carried out to determine whether secretion of ABH antigens was associated falciparum infection. A total of 600 individuals (284 males and 316 females) of age ≥16 years participated in this study after clinical examination and informed consent was obtained. The participants consisted of three groups. The first group consisted of 200 patients with symptomatic malaria. The second group consisted of 200 individuals with asymptomatic malaria while the third group (control group) consisted of 200 apparently healthy individuals without malaria as of the time of investigation. Blood and saliva samples were taken from each participant for examination of malaria parasite and secretor status respectively. Thick and thin Giemsa stained blood smear were prepared for malaria parasite examination and identification. Secretor status was determined among the participants using haemagglutination inhibition technique. The results showed that the proportion of non-secretors in the symptomatic malaria group (30.5%) was significantly higher than that of non-secretors in the control group (20.5%) (χ 2 = 5.264, df = 1, p = 0.022). The proportion of non-secretors in the asymptomatic malaria group (26.5%) was not significantly different from that of non-secretors in the control group (20.5%) (χ 2 = 2.003, df = 1, p = 0.157). We conclude that Non-secretion of ABH substances is associated with acute falciparium malaria.
Epidemiological Study of Cutaneous Leishmaniasis during 2009 to 2014 in Kashan, Iran: A Potential Intra-domiciliary Transmission of the Disease

Aims: In this research, the epidemiological status of cutaneous leishmaniasis was investigated in Kashan city, central of Iran. Study Design and Setting: A cross-sectional study was carried out in Kashan city, central of Iran. Short Communication Study Duration: The study was conducted over 2009 to 2014. Methods: In this study, the demographic and epidemiological data including age, sex, nationality, duration of the disease, number and site of the ulcers for all the patients during 2009 to 2014 were collected from the healthcare centers of Kashan city. The data were finally analyzed by Excel software. Results: The results indicated that 897 persons were suffered from cutaneous leishmaniasis during this 6-year period in Kashan city. Of these patients, 486 (54.2%) and 411 (45.8%) persons were females and males, respectively. The results also showed that the highest and lowest contamination frequencies were occurred in April and in March, respectively. The most burden of this disease was allocated to patients more than 25 years old and the lower rate was occurred in infants less than one year age. Conclusion: The results presented that the prevalence of the urban type of cutaneous leishmaniasis was high in Kashan city. Therefore, the prevention and control measurements should be applied to minimize the prevalence of the disease.
ADDICTION IN PATIENTS WITH SUBSTANCE USE DISORDER

Objective: The aim of this study was to further investigate the relationship between internet addiction and substance use disorder by exploring the prevalence of internet addiction among patients in a substance use disorder treatment clinic and to investigate the frequency with which internet addiction co-occurs with other psychiatric disorders in this population. Method: A survey, containing questions based on the nine criteria for internet gaming disorder proposed in the research appendix to DSM-5, was administered at 24 outpatient clinics for substance use disorders within the Stockholm Centre for Dependency Disorders. Data concerning additional psychiatric diagnoses was collected from patient medical records. A total of 569 patients participated, after excluding those with missing data as well as participants who primarily gambled online, the final sample size was N=462. Results: In total, 4.1% of the surveyed patients with substance use disorder met at least five out of nine internet addiction criteria at a level of “Fairly true” or higher, and reported at least “Some suffering” as a consequence of their internet use. An independent-samples t-test comparing the mean of the total internet addiction score between groups of patients with additional psychiatric diagnoses and the rest of the sample showed that participants with any one additional non-substance related psychiatric diagnose as well as those with an anxiety diagnose had significantly higher internet addiction scores than the rest of the sample. There were no significant differences in mean internet addiction scores between participants with ADHD or depression and the remaining sample. Conclusions: This study provides preliminary evidence to suggest that internet addiction does not constitute a major clinical issue for patients in treatment for substance use disorder, lending little support to the suggestion that internetrelated problem behaviours share pathophysiology with substance use disorders. Although patients with an anxiety disorder reported elevated internet addiction scores compared to the remaining sample this finding should be replicated in a population of patients who report with anxiety disorder as their primary problem. The presence of clinically relevant co-occurrence between internet addiction and substance use disorder needs to be further investigated in larger study populations, using clinical interviews to assess both diagnoses.
NUMERICAL SIMULATION OF HOT ACCRETION FLOWS. I. A LARGE RADIAL DYNAMICAL RANGE AND THE DENSITY PROFILE OF ACCRETION FLOW

Numerical simulations of hot accretion flow, both hydrodynamical and magnetohydrodynamical, have shown that the mass accretion rate decreases with decreasing radius; consequently, the density profile of accretion flow becomes flatter than in the case of a constant accretion rate. This result has important theoretical and observational implications. However, because of technical difficulties, the radial dynamic range in almost all previous simulations usually spans at most two orders of magnitude. This small dynamical range, combined with the effects of boundary conditions, makes the simulation results suspect. In particular, the radial profiles of density and inflow rate may not be precise enough to be used to compare with observations. In this paper, we present a “two-zone” approach to expand the radial dynamical range from two to four orders of magnitude. We confirm previous results and find that from rs to 104rs the radial profiles of accretion rate and density can be well described by and ρ∝r−p. The values of (s, p) are (0.48, 0.65) and (0.4, 0.85) for the viscous parameters α = 0.001 and α = 0.01, respectively. More precisely, the accretion rate is constant (i.e., s = 0) within ∼10rs, but beyond 10rs we have s = 0.65 and 0.54 for α = 0.001 and 0.01, respectively. We find that the values of both s and p are similar in all numerical simulation works irrespective of whether a magnetic field is included or not and what kind of initial conditions are adopted. Such an apparently surprising “common” result can be explained by the most recent version of the adiabatic inflow–outflow model. The density profile we obtain is in good quantitative agreement with that obtained from the detailed observations and modeling of Sgr A* and NGC 3115. The origin and implications of such a profile will be investigated in a subsequent paper.
Effect of perioperative dexmedetomidine on inflammatory mediators and oxidative stress response after surgery : a meta-analysis

This meta-analysis aimed to evaluate effect of perioperative dexmedetomidine on inflammatory response and oxidative stress after surgery. A literature search on databases such as PubMed, Embase, Springer, Science direct and Google Scholar was conducted up to September 2017. The pooled standard mean difference (SMD) and the corresponding 95% confidence intervals (CIs) were calculated using the Revman 5.3. Total 13 studies were included in this meta-analysis. The patients undergoing general anesthesia with dexmedetomidine had lower levels of IL-6 than patients undergoing placebo/normal saline at the end of surgery, but showed similar levels of IL-6 with patients in control groups at 6 h after surgery. Dexmedetomidine anesthesia was associated with the significantly decreased levels of TNF-α at end of surgery and 24 h post-operation and CRP (C-reactive protein) at 24 h postoperation, but not WBC (white blood cell) at 24 h and 72 h post-operation. Meanwhile, the levels of superoxide dismutase (SOD) and malondialdehyde (MDA) at 30 min post-One-lung Ventilation (OLV) were similar between patients undergoing dexmedetomidine anesthesia and normal saline/placebo. The perioperative dexmedetomidine significantly improved the inflammatory response after surgery. However, more studies should be performed to further investigate the effect of perioperative dexmedetomidine on oxidative stress after surgery.
Softening and Ripening of 'Athena' Cantaloupe (Cucumis melo L. var. reticulatus) Fruit at Three Harvest Maturities in Response to the Ethylene Antagonist 1-methylcyclopropene

Three experiments were performed to characterize the physiological responses of an Eastern United States shipper muskmelon (Cucumis melo L. var. reticulatus 'Athena') harvested preripe (¼ slip) and during ripening (half-slip, full-slip) to 1 mLL -1 1-methylcyclopropene (1-MCP), a potent ethylene antagonist effective at significantly extending the time required for climacteric fruit to complete ripening. In the first experiment, preripe fruit were treated with 1-MCP (18 hour, 20 8C) before storage at 15 8C. Softening of preripe 'Athena' was significantly suppressed in response to 1-MCP, with firmness of control and 1-MCP-treated fruit declining '50% and '36% through 12 and 18 days of storage at 15 8C, respectively. By 21 days of storage, firmness of 1-MCP-treated remained near 70 N, minimally within the upper range of whole-fruit firmness values considered acceptable for consumption (50-75 N). Fruit treated with 1-MCP exhibited significantly lower ethylene production, respiratory rates, and electrolyte leakage throughout storage. In a second experiment, muskmelon were treated with 1-MCP (18 hours, 20 8C) at progressively advanced stages of ripening (half- and full- slip stages). Softening was significantly suppressed in half-slip fruit, declining '64% and '23% in control and 1-MCP-treated fruit, respectively, during 16 days of storage at 15 8C. Advanced-ripening, full-slip fruit were similarly affected, softening '60% and '25% in control and 1-MCP-treated fruit, respectively, during 10 days at 15 8C. In a third experiment designed to simulate possible commercial handling protocols, full-slip muskmelon were treated with 1-MCP (24 hours, 10 8C) and held at 10 8C for 5 days before transfer to 20 8C. Mesocarp firmness of 1-MCP and control fruit within 2 days of transfer to 20 8C had decreased '40% and '54%, respectively, compared with values at the start of the experiment. After an additional 2 days at 20 8C, the mesocarp tissue of the respective treatments had softened 42% and 70%. Fruit treated with the ethylene antagonist showed significantly delayed incidence of surface decay and sunken regions compared with control fruit.