Miracle-dz/UniFAR-FTUs huggingface dataset:
The predicted heat strain model considering wet and dynamic thermal insulation for thermal protective clothing: Modification and validation analysis

For guiding the setting of working time, it is necessary to develop a realistic clothing model with accurate thermal physical properties including the effects of human body activities and environments in the predicted heat strain model, especially for the high thermal insulation clothing ensembles and high-temperature conditions. In this study, realistic clothing models, including clothing wet thermal insulation (Icl_w), dynamic thermal insulation (Icl_vw), and convective heat transfer coefficient considering the temperature difference and walking speed (hc_vw), were established. Then, we validated the modified predicted heat strain models combined with realistic clothing parameters. The results revealed that the core temperature of the predicted heat strain model combined with Icl_w, Icl_vw, and hc_vw (deviation of 0.1°C) was significantly more accurate than the original predicted heat strain model (variation of 1.5°C) in the environment of 40°C within 65 min of heat exposure. Our study emphasizes the necessity of ensuring the accuracy of clothing thermal physical properties in the predicted heat strain model to improve validity for the specific conditions investigated.
Performance Feedback in Organizations: Understanding the Functions, Forms, and Important Features

ABSTRACT Feedback surrounds our personal and professional worlds, informing us about what worked and what did not. Within workplace settings, it is important to understand how feedback operates in order to deliberately and carefully craft performance information that, when delivered, generates desirable organizational outcomes. The current paper examines the many potential functions of feedback, including details on how such functions might be established. Behavioral investigations into how to best structure and deliver feedback are detailed, along with considerations of factors that may impact the reception of feedback. Finally, using the current literature as a blueprint, several possible research directions are suggested that would fit well within a behavior analytic perspective.
Improved Survival and Quality of Life Through an Integrative, Multidisciplinary Oncological Approach: Pathophysiological Analysis of Four Clinical Cancer Cases and Review of the Literature

Objectives: According to the National Cancer Institute, the integrative medicine (IM) approach to medical care combines standard medicine with complementary and alternative medicine practices that have proved safe and effective. Methods: We describe the clinical cases of four patients with malignant pleural mesothelioma (MPM), diffuse malignant peritoneal mesothelioma (DMPM), intrahepatic cholangiocarcinoma, and breast cancer (BC) who received supportive treatment (ST) according to an IM approach after the failure of standard cancer treatments or the appearance of serious adverse events caused by antiblastic chemotherapy. The critical role of complementary drugs in reducing the side effects of cancer treatments and normalizing the white cell count is especially apparent in the case of the patient with metastatic BC, who experienced prolonged neutropenia. Results: The IM approach was well-tolerated and had no adverse side effects. It improved the quality of life (QoL) of all patients and in two cases extended overall survival. Conclusion: The extended clinical and instrumental response to IM of the patients with malignant mesothelioma and the improved health-related QoL and good tolerance of the ST demonstrated in all cases support the value of this approach in patients whose cancer therapies have failed but who show a good performance status. Our data require confirmation in a well-designed prospective clinical trial.
Interactions of ignored and attended valence in a valence-detection task with emotional words support the model of evaluative space: an ERP study

ABSTRACT In a valence-detection task with emotional adjectives, 57 participants selectively responded to a predefined target level of valence (negative, positive, or neutral). Event-related potentials of ignored nontargets were examined for a novel type of emotion–attention interaction between a nontarget’s valence and valence of the attentional set. Findings support an extension of the model of evaluative space [Cacioppo, J. T. , Gardner, W. L. , & Berntson, G. G. (1997). Beyond bipolar conceptualizations and measures: The case of attitudes and evaluative space. Personality and Social Psychology Review, 1(1), 3–25. https://doi.org/10.1207/s15327957pspr0101_2], proposing associations of negative and positive stimuli/attentional sets with high and low arousal, respectively. Consistently, in the neutral attentional set involving low arousal, false alarms were more frequent and an average-referenced EPN-like posterior negativity (150–250 ms) was smaller for positive than negative nontarget words. The late positive potential was reduced for positive nontargets in the negative attentional set, but not the reverse, indicating conjoint effects of a negativity bias and distractor-target distance in terms of valence. Finally, data suggest a sensitivity of mastoid-referenced lateral-posterior N170 to inhibition of task-irrelevant affect.
Cichoric Acid May Play a Role in Protecting Hair Cells from Ototoxic Drugs

Ototoxic hearing loss due to antibiotic medication including aminoglycosides and excess free radical production causes irreversible hair cell injury. Cichoric acid, a naturally occurring phenolic acid, has recently been found to exert anti-oxidative and anti-inflammatory properties through its free radical scavenging capacity. The present study aimed to investigate the protective effects of cichoric acid against neomycin-induced ototoxicity using transgenic zebrafish (pvalb3b: TagGFP). Our results indicated that cichoric acid in concentrations up to 5 μM did not affect zebrafish viability during the 2 h treatment period. Therefore, the otoprotective concentration of cichoric acid was identified as 5 μM under 2 h treatment by counting viable hair cells within the neuromasts of the anterior- and posterior-lateral lines in the study. Pretreatment of transgenic zebrafish with 5 μM of cichoric acid for 2 h significantly protected against neomycin-induced hair cell death. Protection mediated by cichoric acid was, however, lost over time. A terminal deoxynucleotidyl transferase dUTP nick-end labeling (TUNEL) assay and FM4-64 staining, respectively, provided in situ evidence that cichoric acid ameliorated apoptotic signals and mechanotransduction machinery impairment caused by neomycin. A fish locomotor test (distance move, velocity, and rotation frequency) assessing behavioral alteration after ototoxic damage revealed rescue due to cichoric acid pretreatment before neomycin exposure. These findings suggest that cichoric acid in 5 μM under 2 h treatment has antioxidant effects and can attenuate neomycin-induced hair cell death in neuromasts. Although cichoric acid offered otoprotection, there is only a small difference between pharmacological and toxic concentrations, and hence cichoric acid can be considered a rather prototypical compound for the development of safer otoprotective compounds.
Lower Extremity Constraint-Induced Movement Therapy Increase Variability in the Intra-Limb Coordination during Walking in Chronic Post-Stroke

Abstract This study aimed to assess the effect of the Lower Extremity Constraint-Induced Movement Therapy (LE-CIMT) intervention on the intra-limb hip-knee coordination and its variability in walking in chronic post-stroke individuals considering the lenses of the dynamic systems approach to motor behavior. Twelve chronic post-stroke individuals received the LE-CIMT intervention for 10 days following all protocol’s recommendations and designed according to individuals’ needs. Before, three days, and 30 days after the intervention, angular kinematics in the sagittal plane of the trunk, hip and knee of both extremities were analyzed. We analyzed joint angles for swing and stance phases of walking, and the intra-limb coordination of hip-knee joints through the vector coding technique. For separate joint angular kinematics, we found differences between affected extremities but no effects of the intervention. However, we observed changes in intra-limb coordination pattern as a function of increased variability after intervention and increased stability at follow-up. These changes follow the predicted pattern from the dynamic systems approach to motor behavior. The immediate decreased stability of the initial pattern could be due to the active exploration of space solution offered by the LE-CIMT and, posteriorly, the stability increased after finding new movement solutions in the real-life environment.
Pengaruh Brand Ambassador Dan Brand Image Terhadap Minat Beli Yang Berdampak Pada Keputusan Pembelian

This research aims to show the influence of brand ambassadors and brand image on buying interest and their impact on purchasing decisions. This study uses a quantitative approach. The research population is Scarlett consumers, whose total is not known with certainty. Sampling using purposive sampling technique and obtained 73 samples. The data analysis technique uses path analysis. The results showed that the brand ambassador did not affect buying interest. The brand image has a positive and significant influence on buying interest. The purchase intention has a positive and significant effect on purchasing decisions. The brand ambassador has a positive and significant effect on purchasing decisions. The brand image has no significant effect on purchasing decisions. The purchase intention cannot mediate the relationship between brand ambassadors and purchase decisions. The purchase intention can mediate the relationship between brand image and purchasing decisions. Companies can use this research in deciding policies and formulating strategies for maintaining a good brand image from consumer perceptions and using brand ambassadors to promote products.
Environmental correlates of phenotypic evolution in ecologically diverse Liolaemus lizards

Abstract Evolutionary correlations between phenotypic and environmental traits characterize adaptive radiations. However, the lizard genus Liolaemus, one of the most ecologically diverse terrestrial vertebrate radiations on earth, has so far shown limited or mixed evidence of adaptive diversification in phenotype. Restricted use of comprehensive environmental data, incomplete taxonomic representation and not considering phylogenetic uncertainty may have led to contradictory evidence. We compiled a 26‐taxon dataset for the Liolaemus gracilis species group, representing much of the ecological diversity represented within Liolaemus and used environmental data to characterize how environments occupied by species' relate to phenotypic evolution. Our analyses, explicitly accounting for phylogenetic uncertainty, suggest diversification in phenotypic traits toward the present, with body shape evolution rapidly evolving in this group. Body shape evolution correlates with the occupation of different structural habitats indicated by vegetation axes suggesting species have adapted for maximal locomotory performance in these habitats. Our results also imply that the effects of phylogenetic uncertainty and model misspecification may be more extensive on univariate, relative to multivariate analyses of evolutionary correlations, which is an important consideration in analyzing data from rapidly radiating adaptive radiations.
Transfer Graph-Driven Rotating Machinery Diagnosis Considering Cross-Domain Relationship Construction

Transfer learning-based fault diagnosis methods borrow source-domain knowledge to achieve diagnosis task for the unlabeled target domain. However, existing research articles mainly lie in feature mapping and model transfer, ignoring the relationship between cross-domain samples. Once connections between cross-domain samples with the same label can be constructed, label propagation will be easier even if there is a cross-domain distribution discrepancy. In this article, a transfer graph-driven rotating machinery diagnosis considering cross-domain relationship construction is proposed. Specifically, signal spectrum is extracted by fast Fourier transform mapping raw signals to identical feature space. Transfer graphs are constructed by the Euclidean distance between nodes, where the relationships between the same domain samples, even cross-domain samples, are established. Then, the graph convolutional network (GCN), trained by source-domain samples and less target-domain samples, is utilized for cross-domain diagnosis tasks. The experimental results demonstrate the effectiveness of the proposed method. In addition, trained GCN enables diagnosing on newly constructed target-domain graphs. It shows the ability to continuously learn new transferable knowledge.
Interleukin‐17A and interleukin‐22 production by conventional and non‐conventional lymphocytes in three different end‐stage lung diseases

The contribution of adaptive vs. innate lymphocytes to IL‐17A and IL‐22 secretion at the end stage of chronic lung diseases remains largely unexplored. In order to uncover tissue‐ and disease‐specific secretion patterns, we compared production patterns of IL‐17A and IL‐22 in three different human end‐stage lung disease entities.
Biglycan Is a Novel Mineralocorticoid Receptor Target Involved in Aldosterone/Salt-Induced Glomerular Injury

The beneficial effects of mineralocorticoid receptor (MR) antagonists (MRAs) for various kidney diseases are established. However, the underlying mechanisms of kidney injury induced by MR activation remain to be elucidated. We recently reported aldosterone-induced enhancement of proteoglycan expression in mitral valve interstitial cells and its association with fibromyxomatous valvular disorder. As the expression of certain proteoglycans is elevated in several kidney diseases, we hypothesized that proteoglycans mediate kidney injury in the context of aldosterone/MR pathway activation. We evaluated the proteoglycan expression and tissue injury in the kidney and isolated glomeruli of uninephrectomy/aldosterone/salt (NAS) mice. The MRA eplerenone was administered to assess the role of the MR pathway. We investigated the direct effects of biglycan, one of the proteoglycans, on macrophages using isolated macrophages. The kidney samples from NAS-treated mice showed enhanced fibrosis and increased expression of biglycan accompanying glomerular macrophage infiltration and enhanced expression of TNF-α, iNOS, Nox2, CCL3 (C-C motif chemokine ligand 3), and phosphorylated NF-κB. Eplerenone blunted these changes. Purified biglycan stimulated macrophages to express TNF-α, iNOS, Nox2, and CCL3. This was prevented by a toll-like receptor 4 (TLR4) or NF-κB inhibitor, indicating that biglycan stimulation is dependent on the TLR4/NF-κB pathway. We identified the proteoglycan biglycan as a novel target of MR involved in MR-induced glomerular injury and macrophage infiltration via a biglycan/TLR4/NF-κB/CCL3 cascade.
Understanding employee travel behaviours in response to workplace relocation: a case study comparing commuting patterns between Subiaco and Perth, Western Australia

ABSTRACT Our built environments offer distinct variables that impact behaviour – throughout the world, and equally within Western Australia. However, an in-depth analysis of extant literature indicates that influencing human behaviour is difficult in the absence of a ‘disruption’ event. Accordingly, this organization-level study examined the disruptive effects of relocating from a Subiaco office to a new office in Perth’s Central Business District on the commute habits of its built-environment professional employees. The relocation occurred during a ‘non-lockdown’ period between July and August 2021 (southern hemisphere winter). The study sought to determine if an office relocation constituted a sufficient ‘disruption’ to affect employees’ commute behaviours, and in contrast to state and national figures, to quantify how micro-communities revise and develop commuting habits in response to changing circumstances. It was expected that the shift would increase public transportation reliance, lengthen commute times, and increase expenditure. The study applied a two-part purposive survey using frequencies and a one-sample Chi-Square test at the 95% confidence level. The distance between the two locations and projected trip times through various modes was calculated using Google Maps. The findings indicate that both Subiaco and Perth had higher public transportation utilisation when compared to state and national numbers as a multi-modal means of commuting. Furthermore, car reliance decreased and general satisfaction with commuting choices increased for the Perth study. This suggests that multi-modal public transportation commute alternatives provided a cost-effective and efficient, alternative. The study identified social value and preference propositions beyond return-on-investment for improving existing idle city assets. Lastly, the study contributes to evolving contemporary cross-disciplinary discourse and body of knowledge in human geography, urban community development, and transportation, and sought to concomitantly determine the potential to further extend this research through concurrent collection of employee daily step count data.
Genomic Characteristics of a Chicken Infectious Anemia Virus in Contaminated Attenuated Vaccine

Chicken infectious anemia virus (CIAV) can be transmitted by contaminated live vaccines, and causes huge economic losses. This study evaluated the contamination status of CIAV in 24 batches of vaccines by recombinase-aided amplification assay (RAA), fluorescence quantitative PCR and dot blot assay, and then found a contaminated attenuated vaccine. The whole genome of the CIAV contaminant was then sequenced and named JS2020-PFV (Genbank accession number: MW234428, 2296bp). It showed 94.5 to 99.9% identities with reference strains and shared the closest evolution relationship with AB1K strain which was isolated from a chicken farm in Turkey. All of these suggested that the use of CIAV contaminated live vaccine may be one of the reason for its epidemic in poultry.
Static Load Test on Instrumented Pile – Field Data and Numerical Simulations

Abstract Static load tests on foundation piles are generally carried out in order to determine load – the displacement characteristic of the pile head. For standard (basic) engineering practices this type of test usually provides enough information. However, the knowledge of force distribution along the pile core and its division into the friction along the shaft and the resistance under the base can be very useful. Such information can be obtained by strain gage pile instrumentation [1]. Significant investigations have been completed on this technology, proving its utility and correctness [8], [10], [12]. The results of static tests on instrumented piles are not easy to interpret. There are many factors and processes affecting the final outcome. In order to understand better the whole testing process and soil-structure behavior some investigations and numerical analyses were done. In the paper, real data from a field load test on instrumented piles is discussed and compared with numerical simulation of such a test in similar conditions. Differences and difficulties in the results interpretation with their possible reasons are discussed. Moreover, the authors used their own analytical solution for more reliable determination of force distribution along the pile. The work was presented at the XVII French-Polish Colloquium of Soil and Rock Mechanics, Łódź, 28–30 November 2016.
Challenges to incorporating social and economic factors into cumulative effects assessments in Canada’s marine conservation areas

The cumulative effects of human stressors are threatening marine ecosystems. While spatial management tools such as marine conservation areas can help mitigate cumulative effects, several decision-making challenges remain. A limited availability of information and lack of knowledge, inconsistent management approaches, and ineffective consideration of social-ecological interactions hinders current cumulative effects assessment and management efforts. We examined if and how ocean managers assess cumulative effects and incorporate them into their management practices. A survey of the three Canadian federal departments responsible for marine conservation areas was conducted, and focused on the extent to which social and economic factors are considered. Managers seemed to favor ecological factors over social and economic ones when evaluating cumulative effects, such as when defining the spatial and temporal scales to use in their assessments. Managers also indicated a need for greater access to social and economic data and information to improve their assessment and management decisions. Lastly, the lack of a standardized cumulative effects assessment framework and fragmented management approaches appeared to limit managers’ ability to adequately incorporate social and economic factors into assessments. The survey results indicated that a cumulative effects assessment framework that explicitly includes social and economic factors in addition to an enhanced understanding of the suite of factors that influence social-ecological interactions should be developed. This type of framework is essential to help achieve the long-term management solutions required to conserve the health and integrity of Canada's oceans and beyond.
Changes in the vegetation and water cycle of the Ecuadorian páramo during the last 5000 years

We analyzed changes in the long-term vegetation cover and in fire activity over the past 5000 years in the Ecuadorian páramo using a sediment core from Papallacta (Ecuador). The chronology is constrained by three tephra layers and 32 AMS 14C ages, and 168 samples yielded a high-resolution record of environmental changes. We estimated the upslope wind convectivity as the ratio between pollen transported from the Andean cloud forest and Poaceae pollen to distinguish changes in atmospheric moisture from changes in soil moisture. The record showed that the two sources of moisture, either from year-round adiabatic cloud dripping linked to SASM activity or to ENSO variability at decadal-scale, influenced vegetation-cover changes. Between 5000 and 2450 cal yr BP, both soil moisture and biomass burning were higher than after 2450 cal yr BP. The shift between the two states matches the zonal increase in summer insolation that drove the ITCZ to its southernmost position. Our results underline resilience to volcanic activity, the importance of the upslope convective dripping with the lowest convective index observed at ~4500 cal yr BP, the anomalous last century with the highest convective activity and the driest soil conditions recorded in the last 5000 years, the recent increase in fire activity and the link between soil moisture and the position of the ITCZ.
Implementation of Just-In-Time Policies in Supply Chain Management

This Paper focuses on the implementation of Just-In-Time (JIT) in Supply Chain Management (SCM) context. Three Pull Control Policies (PCPs), developed for controlling the inventory level, are discussed. Kanban, ConWIP, and a hybrid PCP, are recognized for implementation in multi-echelon, multi-stage, and multi-product supply chains. The performance of each policy is measured through three measurement criteria. Considering the uncertainty, the performances of policies are evaluated via a Fuzzy AHP method. For, identification, performance measurement, and evaluation of PCPs the study proposes an integrated approach. The approach explains the PCPs mechanisms, measurement criteria formulations, and multi criteria decision making methods. Finally, the solution approach is examined through a case study