Miracle-dz/UniFAR-FTUs huggingface dataset:
Characterization of gasoline combustion with laser and spark ignition

The combustion of gasoline-air mixtures in a constant-volume combustion chamber with an initial condition of 0.1 MPa pressure and 363 K temperature is experimentally investigated with laser ignition generated by a Q-switched Nd:YAG laser (wavelengths of 532 and 1064 nm). Spark ignition is also tested, and the results are used as the benchmark. Combustion chamber pressure is measured by a piezoelectric pressure transducer, and recorded using a digital oscilloscope. When the equivalence ratio is swept from 1.2 to 1.8, laser and spark ignition show marginal differences in pressure rise rate and peak pressure. The maximum pressure rise rate and the maximum peak pressure are obtained at equivalence ratios of 1.6 and 1.8 for laser ignition and spark ignition, which are 39.4 MPa/µs and 0.68 MPa for the laser wavelength of 532 nm, 38.8 MPa/µs and 0.67 MPa for the laser wavelength of 1064 nm, and 38.1 MPa/µs and 0.67 MPa for spark ignition, respectively. When the equivalence ratio is reduced below 1.2, the pressure rise rate and peak pressure of the laser ignition are significantly higher than those of spark ignition, and the lean limit for laser ignition is also wider than that of spark ignition; therefore, laser ignition is more favorable for lean combustion. For both the laser and spark ignitions, the ignition energy demonstrated a limited impact on both the pressure rise rate and peak pressure. Heat release rate in the combustion chamber is calculated, and the results show that variations of heat release are in accordance with variations of the pressure history. 中文概要题 目汽油激光诱导火花点火与电火花点火燃烧过程对比研究目 的激光诱导火花点火 (简称激光点火) 是取代传统的靠近缸壁的单点电火花点火以实现稀薄燃烧、提高热效率和改善排放的新型点火方式之一。 本文通过对比分析两种点火方式在定容弹中的点火及燃烧过程的压力上升率、最大爆发压力及放热率为激光点火技术在内燃机中的应用提供设计过程的参考依据。 创新点1. 同时进行两种点火方式的试验, 保证对比研究的准确性; 2. 激光点火采用532 nm 和1064 nm 波长的两种激光进行对比; 3. 直接采用汽油进行研究。 方 法通过记录不同当量比的汽油空气混合气在定容燃烧弹内激光点火 (532 nm 和1064 nm 波长) 及电火花点火的燃烧过程压力变化: 1. 对比分析三种点火情况的压力上升率和最大爆发压力; 2. 通过公式计算, 对比分析三种点火情况的放热率。 结 论1. 532 nm 与1064 nm 波长激光点火的压力上升率和最大爆发压力都在当量比为1.8 时出现最大值, 其中532 nm 波长激光为39.4 MPa/μs 和0.68 MPa, 1064 nm 波长激光为38.8 MPa/μs 和0.67 MPa; 而电火花点火的压力上升率和最大爆发压力则在当量比为1.6 时出现最大值, 分别为38.1 MPa/μs 和0.67 MPa; 2. 激光点火的稀燃极限相对电火花点火对应的当量比更小; 3. 三种点火类型的放热率规律与压力上升率变化规律一致。
The simulation of a landslide-induced surge wave and its overtopping of a dam using a coupled ISPH model

In this paper, a landslide-induced surge wave and its overtopping of a dam is simulated using a coupled ISPH model. In the model, the mirror particle treatment was employed to simulate the moving structures and a particle symmetry criterion was enforced for free surface judgment. A telescopic boundary is presented for the landslide body motion treatment. The model is first used to simulate the two types of surge wave induced by submarine and aerial landslides and the simulation results are compared to the previously published experimental data. Then, in order to study landslide-induced wave propagation and especially the overtopping of a dam, laboratory experiments were conducted in which the landslide motion, the wave gauge results and the total overtopping volume were presented and compared to the numerical results. It was found that the present numerical model can accurately simulate the entire process of surge wave generation, propagation and overtopping of a dam.
Reliability and Validity of Six Selected Observational Methods for Risk Assessment of Hand Intensive and Repetitive Work

Risk assessments of hand-intensive and repetitive work are commonly done using observational methods, and it is important that the methods are reliable and valid. However, comparisons of the reliability and validity of methods are hampered by differences in studies, e.g., regarding the background and competence of the observers, the complexity of the observed work tasks and the statistical methodology. The purpose of the present study was to evaluate six risk assessment methods, concerning inter- and intra-observer reliability and concurrent validity, using the same methodological design and statistical parameters in the analyses. Twelve experienced ergonomists were recruited to perform risk assessments of ten video-recorded work tasks twice, and consensus assessments for the concurrent validity were carried out by three experts. All methods’ total-risk linearly weighted kappa values for inter-observer reliability (when all tasks were set to the same duration) were lower than 0.5 (0.15–0.45). Moreover, the concurrent validity values were in the same range with regards to total-risk linearly weighted kappa (0.31–0.54). Although these levels are often considered as being fair to substantial, they denote agreements lower than 50% when the expected agreement by chance has been compensated for. Hence, the risk of misclassification is substantial. The intra-observer reliability was only somewhat higher (0.16–0.58). Regarding the methods ART (Assessment of repetitive tasks of the upper limbs) and HARM (Hand Arm Risk Assessment Method), it is worth noting that the work task duration has a high impact in the risk level calculation, which needs to be taken into account in studies of reliability. This study indicates that when experienced ergonomists use systematic methods, the reliability is low. As seen in other studies, especially assessments of hand/wrist postures were difficult to rate. In light of these results, complementing observational risk assessments with technical methods should be considered, especially when evaluating the effects of ergonomic interventions.
FORWARD-BACKWARD STOCHASTIC DIFFERENTIAL EQUATIONS, LINEAR QUADRATIC STOCHASTIC OPTIMAL CONTROL AND NONZERO SUM DIFFERENTIAL GAMES

In this paper, we use the solutions of forward-backward stochastic differential equations to get the explicit form of the optimal control for linear quadratic stochastic optimal control problem and the open-loop Nash equilibrium point for nonzero sum differential games problem. We also discuss the solvability of the generalized Riccati equation system and give the linear feedback regulator for the optimal control problem using the solution of this kind of Riccati equation system.
Clinical Characteristics, Treatment Considerations, and Outcomes of Infants with Rhabdomyosarcoma

Simple Summary Rhabdomyosarcoma (RMS) is the most common type of soft tissue sarcoma among infants. The clinical characteristics and biology of RMS among infants are distinct from those of older children with RMS. The management of infants with RMS follows a parallel approach of risk-stratification and treatment with multimodality chemotherapy in combination with surgery and/or radiation. but with a few caveats. Modification of chemotherapy regimens is often needed to reduce the risk of excessive treatment-related morbidity due to developmentally immature organs. Adequate surgical resection is more challenging due to the technical difficulties associated with large tumors arising from critical structures in small-sized patients. Similarly, irradiating developing organs can impair long-term function or form and increase the risk of secondary malignant neoplasms. A few clinical trials conducted by international cooperative groups have addressed the challenges of managing infants with RMS and their outcomes. Abstract RMS most commonly presents in children and adolescents, however a subset of tumors are diagnosed in infants under one year of age. Due to the rarity of infant RMS, utilization of different treatment approaches and goals, and small sample sizes, the published studies of infants with RMS have yielded heterogeneous results. In this review, we discuss the outcomes of infants with RMS treated in various clinical trials and the strategies that various international cooperative groups have employed to reduce the morbidity and mortality related to treatment without compromising the overall survival of this population. This review discusses the unique scenarios of diagnosing and managing congenitals or neonatal RMS, spindle cell RMS and relapsed RMS. This review concludes by exploring novel approaches to diagnosis and management of infants with RMS that are currently being studied by various international cooperative groups.
Detection of IgA and IgG Antibodies against the Structural Proteins of SARS-CoV-2 in Breast Milk and Serum Samples Derived from Breastfeeding Mothers

Background: COVID-19 vaccination or natural infection is associated with the development of immunity. The search of IgA and IgG antibodies against all the structural proteins (spike, nucleocapsid, membrane, and envelope) of SARS-CoV-2 in breastfeeding mothers is associated with immunity that can help the newborn avoid development of the infection. Methods: In this study, we analyzed 30 breastfeeding women that provided samples of breast milk and serum and evaluated the presence of IgA, total IgG, and subclasses against the structural proteins of SARS-CoV-2. Results: We reported a high seroprevalence to IgA (76.67–100%) and negativity to IgG against all analyzed proteins in breast milk. Seroprevalence in serum samples was around 10–36.67% to IgA and 23.3–60% to IgG. Finally, we detected the presence of the subclasses IgG1, IgG2, and IgG4 against all the structural proteins of SARS-CoV-2. Conclusions: This work provides evidence of the presence of IgA and IgG antibodies against the four structural proteins of SARS-CoV-2 in breast milk and serum samples derived from breastfeeding women, which can confer immunity to the newborn.
Foreign Language Anxiety and Chinese Students

This study attempts to demonstrate that Chinese students studying in the UK have foreign language classroom anxiety and tries to identify the causes of this anxiety. Although there have been many studies on language anxiety, there are no studies specifically on the international student population. This study aims to make a contribution in this regard. It used an online, anonymously completed questionnaire to collect data from 31 students.
The Transcriptome of Chicken Migratory Primordial Germ Cells Reveals Intrinsic Sex Differences and Expression of Hallmark Germ Cell Genes

Primordial germ cells (PGCs) are germline-restricted embryonic cells that form the functional gametes of the adult animal. The use of avian PGCs in biobanking and producing genetically modified birds has driven research on the in vitro propagation and manipulation of these embryonic cells. In avian species, PGCs are hypothesized to be sexually undetermined at an early embryonic stage and undergo differentiation into an oocyte or spermatogonial fate dictated by extrinsic factors present in the gonad. However, chicken male and female PGCs require different culture conditions, suggesting that there are sex-specific differences, even at early stages. To understand potential differences between male and female chicken PGCs during migratory stages, we studied the transcriptomes of circulatory stage male and female PGCs propagated in a serum-free medium. We found that in vitro cultured PGCs were transcriptionally similar to their in ovo counterparts, with differences in cell proliferation pathways. Our analysis also revealed sex-specific transcriptome differences between male and female cultured PGCs, with notable differences in Smad7 and NCAM2 expression. A comparison of chicken PGCs with pluripotent and somatic cell types identified a set of genes that are exclusive to germ cells, enriched in the germplasm, and associated with germ cell development.
Effect of Selenium Deficiency on the Development of Overt Hepatic Encephalopathy in Patients with Chronic Liver Disease

Selenium is an essential trace element to maintain good health. This retrospective study investigated the prevalence of selenium deficiency and its effect on overt hepatic encephalopathy (OHE) in patients with chronic liver disease (CLD). Patients who underwent serum selenium level measurement between January 2021 and April 2022 were enrolled. The factors associated with selenium deficiency (≤10 µg/dL) and the association between selenium deficiency and OHE were analyzed. Among 98 eligible patients, 24% were observed to have selenium deficiency, with a median serum selenium level of 11.8 µg/dL. The serum selenium levels were significantly lower in patients with cirrhosis than in those with chronic hepatitis (10.9 µg/dL vs. 12.4 µg/dL; p = 0.03). The serum selenium levels were negatively correlated with mac-2 binding protein glycan isomer, the FIB-4 index, albumin-bilirubin (ALBI) score, and Child–Pugh score. The ALBI score remained significantly associated with selenium deficiency (odds ratio, 3.23; 95% confidence interval [CI], 1.56–6.67). During a median follow-up period of 2.9 months, nine patients experienced OHE. Selenium deficiency was associated with OHE (hazard ratio, 12.75; 95% CI, 2.54–70.22). Selenium deficiency is highly prevalent in patients with CLD and is associated with an increased risk of OHE development.
Simple and Highly Efficient Detection of PSD95 Using a Nanobody and Its Recombinant Heavy-Chain Antibody Derivatives

The post-synaptic density protein 95 (PSD95) is a crucial scaffolding protein participating in the organization and regulation of synapses. PSD95 interacts with numerous molecules, including neurotransmitter receptors and ion channels. The functional dysregulation of PSD95 as well as its abundance and localization has been implicated with several neurological disorders, making it an attractive target to develop strategies able to monitor PSD95 accurately for diagnostics and therapeutics. This study characterizes a novel camelid single-domain antibody (nanobody) that binds strongly and with high specificity to rat, mouse and human PSD95. This nanobody allows for a more precise detection and better quantification of PSD95 in various biological samples. We expect that the flexibility and unique performance of this thoroughly characterized affinity tool will help to further understand the role of PSD95 in normal and diseased neuronal synapses.
Over 23% Efficiency Under Indoor Light in Gallium-Doped Zinc Oxide Electron-Transport-Layer-Based Inverted Organic Solar Cell to Power IoT Devices

Inverted structured organic solar cells (OSCs) have recently attracted attention due to their greater stability and performance above conventional structured OSCs. Consequently, under indoor lighting, OSCs have excellent power conversion efficiency (PCE). Indoor OSC may be a useful power source for a variety of electrical devices connected to the Internet of Things network. An inverted structured OSC, the electron transport layer (ETL) is crucial. Inverted OSCs have been constructed with variety of metal oxides-based ETL. Zinc oxide (ZnO) is one of the best options among them because of its high transparency and stability, but its lower electron mobility is the key reason for the ZnO ETL-based inverted OSCs’ lower PCE. Moreover, very few studies have been conducted on the application of inverted structured OSCs for indoor light harvesting. We fabricate ZnO and gallium (Ga)-doped ZnO (GZO) ETL-based inverted structured OSCs with an poly [(2,6-(4,8-bis(5-(2-ethylhexyl)thiophen-2-yl)-benzo]1,2-b:4,5-b’]dithiophene))-alt-(5,5-(1’,3’-di-2-thienyl-5’,7’-bis(2-ethylhexyl)benzo[1’,2’-c:4’,5’-c’]dithiophene-4,8-dione)]: [6], [6]-phenyl-C71-butyric acid methyl ester (PBDB-T:PC70BM) active layer and evaluate them using a light-emitting diode (LED) (1000 lx). To optimize the doping concentration, we have varied the concentration of Ga in the GZO. The findings demonstrate that only by doping the ETL of the inverted structured OSC, the PCE may be significantly enhanced. Under a 1000-lx LED illumination, the device using undoped ZnO as the ETL shows a maximum of 15.56% PCE. The OSC with GZO as the ETL with an optimized concentration of Ga (2 at.%) exhibits a maximum of 23.42% PCE under a 1000-lx LED.
Supplemental fixation of distal femur fractures: a review of biomechanical and clinical evidence

Background: Fixation of distal femur fractures with lateral locking plates has relatively high rates of clinical failure. Supplemental fixation has shown promising results, and may reduce rates of fixation failure or nonunion. This review aimed to assess the biomechanical and clinical evidence regarding the use of supplemental fixation of distal femur fractures. Methods: PubMed, Embase, and Cochrane databases were searched for English language studies up to December 4, 2020, identifying 1,829 studies. Biomechanical studies that assessed fracture displacement, load/cycles to failure, or construct stiffness and clinical studies that assessed fixation failure or nonunion after supplemental fixation of distal femur fractures were included. Studies with sample size ≤5, ORIF with non-locking plates, periprosthetic distal femoral fractures, nonunions or revision surgeries were excluded. Results: Seventeen studies were included, of which 8 were biomechanical and 9 clinical. Overall, biomechanical studies demonstrated increased construct stability and load to failure with various supplemental fixation strategies. Clinical studies demonstrated more mixed outcomes for nonunion and fixation failure rate among the various techniques. Conclusions: Biomechanical studies have demonstrated potential benefits of these strategies, but there remains a dearth of high-quality evidence evaluating their effect on clinical outcomes. Prospective RCTs are necessary to address these issues and confirm the results in the existing literature. Level of Evidence: IID
Clinical and ultrasound characteristics distinguishing benign and malignant thyroid nodules in Johannesburg, South Africa

Background: The detection of thyroid nodules is increasingly common in clinical practice owing to the widespread use of ultrasonography. Objectives: The aims of this study were to describe the clinical and biochemical characteristics of patients undergoing fine-needle aspiration (FNA) of thyroid nodules and to assess the ultrasound, cytologic and, where relevant, histologic features of thyroid nodules in this cohort. Methods: A retrospective study was conducted of 313 patients undergoing FNA at a private hospital in Johannesburg from October 2015 to July 2019. Demographic, clinical and biochemical data were recorded. Ultrasound features were graded according to the American Thyroid Association (ATA) guidelines and cytology was reported according to the Bethesda System for Reporting Thyroid Cytopathology. Results: The mean (SD) age of patients in this study was 48.0 (12.7) years and 250 (80.1%) were female. White and Asian/Indian patients made up 79% of the cohort. Cytology results showed the following (n [%]): benign, 272 (86.9); indeterminate, 15 (4.79); suspicious/malignant, 25 (7.99). Sonographic characteristics associated with malignancy were microcalcifications and hypoechogenicity (OR [95% CI], p-value: 3.93 (1.62, 9.53), p = 0.001and 2.34 (1.01, 5.41), p = 0.04, respectively). There was an association with the composite ATA score and malignancy (3.59 [2.06, 6.25], p < 0.0005). Conclusion: Thyroid ultrasound and FNA are important diagnostic modalities in identifying clinically relevant thyroid nodules. Concordance was shown with the ATA guidelines, Bethesda System for Reporting Thyroid Cytopathology and malignant histology, which validates their accuracy in the local population.
Emotional and relational regulation of children and youth in residential care

Family relationships have been shown to play an important role in the way children/youth evaluate themselves, influencing their emotional and relational regulation, more specifically, their self-concept, self-esteem, perception of social support and behavior. In order to compare the adjustment of children/youth living in residential care and in family, 169 children/youth aged between 10 and 21 years were studied, 62 living in residential care units and 107 with their families, 93 females and 76 males. The Piers-Harris Self-concept Rating Scale, Rosenberg Self-esteem Scale, Procidano and Heller's Perception of Social Support from Friends and Family and Buss and Perry's Aggressiveness Questionnaire were applied via google forms and in person. The results showed that children and youngsters in residential care show statistically significant differences from those who live with their families in all the parameters analyzed. They are more fragile in terms of self-concept (except for the anxiety domain) and self-esteem, show a lower perception of social support from peers and family, and show a higher perception of aggressiveness, both in general and in the instrumental, affective and cognitive dimensions. We conclude that all participants showed weaknesses in terms of anxiety management, and that institutionalized children/youth were more psychologically and relationally maladjusted and more aggressive, thus demonstrating the urgency for a multidisciplinary intervention in this population, by promoting personal and relational skills.
PROBABILITIES OF BREAKING WAVE CHARACTERISTICS

Utilizing the hydrodynamic relationships for shoaling and refraction of waves approaching a shoreline over parallel bottom contours a procedure is developed to transform an arbitrary probability density of wave characteristics in deep water into the corresponding breaking characteristics in shallow Water A number of probability distributions for breaking wave characteristics are derived m terms of assumed deep water probability densities of wave heights wave lengths and angles of approach Some probability densities for wave heights at specific locations in the surf zone are computed for a Rayleigh distribution in deep water The probability computations are used to derive the expectation of energy flux and its distribution.
EFFECTS OF PLUNGING MOTION ON UNSTEADY AERODYNAMIC BEHAVIOR OF AN AIRCRAFT MODEL IN COMPRESSIBLE FLOW

Abstract– Aspects of pitching and plunging motions on unsteady aerodynamic behavior of an aircraft model were studied. Extensive wind tunnel tests were performed on a standard dynamics model, SDM, oscillating in both pitch and plunge modes. Up to now, there has been little or no result on the plunging behavior of an aircraft or missile as a whole and the present experiments can be considered as one of the first attempts to study the compressible flow field over a model undergoing both pitching and plunging motions. The experiments involved measuring normal force and pitching moment of the model at Mach numbers of 0.4, 0.6 and 1.5 and oscillation frequencies of 1.25, 2.77 and 6.00 Hz. The longitudinal dynamic derivatives were then calculated from the measured data. The pitching results have been compared with the available data on the same model and good agreement has been achieved. However no plunging data on the same or a similar model was available in the literature to be compared with the present findings.