Miracle-dz/UniFAR-FTUs huggingface dataset:
Scholarly Commons @ Baptist Health South Florida Scholarly Commons @ Baptist Health South Florida

Background: When treated conservatively, unstable distal clavicle fractures demonstrate a high symptomatic nonunion rate. While a variety of surgical techniques have been described, many of these techniques are associated with high failure rates and hardware-related complications. The surgical technique used in this study has shown promising biomechanical results; however, long-term clinical results have not yet been described. Purpose: To assess the clinical and radiological outcomes of a surgical technique for fixing displaced distal clavicle fractures using a combination of cortical button fixation and coracoclavicular (CC) ligament reconstruction. Study Design: Case series; Level of evidence, 4. Methods: We conducted a retrospective review of 22 consecutive patients with displaced, unstable Neer type II or V distal clavicle fractures who underwent this surgical technique from 2012 to 2019. Primary outcome variables were radiographic union, patient satisfaction, and postoperative shoulder function. Preoperative and postoperative University of California, Los Angeles (UCLA), and American Shoulder and Elbow Surgeons (ASES) scores were compared. Secondary outcome variables included intraoperative complications, postoperative complications, time to radiographic union, and preoperative and postoperative CC distance. Quality of life was assessed using preoperative and postoperative 36-Item Short Form Health Survey (SF-36) scores. Results: Nearly all (21/22) patients were available for a final review; 1 patient was lost to follow-up at 2 weeks. All 21 patients achieved radiographic union by 4 months (mean, 60.38 days; range, 41-84 days; 95% CI, 53.80-66.96 days). All patients were satisfied with the surgicalprocedureandtheirfunctionaloutcome.ThemeanUCLAscoreimprovedfrom5. 36(95%CI,4.14-6.60)preoperativelyto32.52 (95% CI, 30.56-34.48) postoperatively (mean difference, 27.14; P < .001). The mean ASES score improved from 16.23 (95% CI, 9.79-22.67) preoperatively to 88.11 (95% CI, 81.82-94.40) postoperatively (mean difference, 71.91; P < .001). Statistically significant improvementsinSF-36scoreswereseeninthephysicalfunctioning,rolelimitationsduetophysicalhealth,pain,socialfunctioning,and emotionalwell-beingcategories.Therewere3postoperativecomplications,including1patientwithaminorcomplicationsecondaryto hardwareirritation,1patientwithadhesivecapsulitis,and1patientwithwounddehiscencerequiringwoundclosure. Conclusion: We describe a surgical technique for fixing displaced distal clavicle fractures using a combination of cortical button fixation and CC ligament reconstruction that resulted in a 100% union rate and excellent clinical outcomes with acceptable complications.
Genome-Wide Identiﬁcation and Analysis of ZF-HD Gene Family in Moso Bamboo ( Phyllostachys edulis )

: Zinc ﬁnger-homeodomain (ZF-HD) proteins play essential roles in plant growth, development and stress responses. However, knowledge of the expression and evolutionary history of ZF-HD genes in moso bamboo remains limited. In this study, a total of 24 ZF-HD genes were found unevenly distributed on 12 chromosomes in moso bamboo ( Phyllostachys edulis ). Phylogenetic analysis indicated that PeZF-HD s were divided into two subfamilies: ZHD and MIF. The ZHD subfamily genes were further classiﬁed into seven groups according to their orthologous relationships among the rice and Arabidopsis ZF-HD gene family. The gene structures and conserved motifs of PeZF-HD s were analyzed. Whole-genome duplication (WGD) or segmental duplication promoted the evolution and expansion of the moso bamboo ZF-HD gene family. Ka/Ks ratios suggested that the twenty-four duplication pairs had undergone purifying selection. Promoter analysis showed that most PeZF-HD s contained cis -elements associated with stress responses and hormones. Expression analysis demonstrated that many PeZF-HD s were responsive to abiotic stress treatment. Overall, this work investigated PeZF-HD genes in moso bamboo using bioinformatic approaches. The evolutionary research on gene structure, motif distribution and cis -regulatory elements indicated that PeZF-HD s play distinct roles in biological processes, which provides a theoretical basis for exploring the physiological functions of ZF-HD s and selecting candidate stress-related genes in moso bamboo.
Vertical Proﬁles of Radar Reﬂectivity Factor in Intense Convective Clouds in the Tropics

This study is based on the analysis of 10 years of data for radar reﬂectivity factor Z e as derived from the TRMM Precipitation Radar (PR) measurements. The vertical structure of active convective clouds at the PR pixel scale has been extracted by deﬁning two types of convective cells. The ﬁrst one is cumulonimbus tower (CbT),whichcontains Z e $ 20dB Z at12-kmaltitudeandis atleast9kmdeep.The otherisintenseconvective cloud (ICC), which belongs to the top 5% of the population of the Z e distribution at a prescribed reference height. Here two reference heights (3 and 8 km) have been chosen. Regional differences in the vertical structure of convective cells have been explored by considering 16 locations distributed across the tropics and twolocationsinthesubtropics.Thechoiceofoceaniclocationsisbasedontheseasurfacetemperature;thatof the land locations is based on propensityfor intense convection. Oneof the main ﬁndings of thestudy isthe close similarity in the average vertical proﬁles of CbTs and ICCs in the mid-and lower troposphere across the ocean basins whereas differences over land areas are larger and depend on the selected reference height. The foothills of the western Himalaya, southeastern South America, and the Indo-Gangetic Plain contain the most intense CbTs; equatorial Africa, the foothills of the western Himalaya, and equatorial South America contain the most intense ICCs. Close similarity among the oceanic proﬁles suggests that the development of vigorous convective cells over warm oceans is similar and that understanding gained in one region is extendable to other areas.
: New insight in Inflammatory Acne Pathogenesis

Background: Acne is an inflammatory skin condition of pilosebaceous unit. Its pathogenesis is multifactorial with a central role of inflammatory and pro inflammatory cytokines mediators. Downregulated Kruppel like factor 2 (KLF2) leads to rapid secretion of many cytokines that are involved in acne pathogenesis.
COVID-19 Waste as Source of Microplastics in the Environment: Implication for Aquatic Species, Human, and Remediation Measures- A Review

Coronavirus (COVID-19) pandemic ushered in a new era that led to the adjustments of diverse ecosystems. The pandemic restructured the global socio-economic events which prompted several adaptation measures as a response mechanism to cushion the negative impact of the disease pandemic. Critical health safety actions were impera-tive to curtail the spread of the disease such as wearing personal protective equipment (PPEs), masks, goggles, and using sanitizers for disinfection purposes. The daily de-mands for the products by individuals and medical personnel heightened their pro-duction and consumption, leading to a corresponding increase of COVID-19 wastes in the environment following indiscriminate waste disposal and poor waste management. The persistent occurrence of COVID-19 wastes aggravated microplastics (MPs) con-tamination in the aquatic ecosystem following the breakdown of PPEs-based plastics via oxidation, fragmentation, and photo-degradation actions. These MPs are transport-ed in the aquatic environment via surface runoff and wind action, apart from discrete sources. MPs' presence in the aquatic systems is not without repercussions. Ingestion of MPs by aquatic organisms can cause several diseases (e.g., poor growth, oxidative distress, neurotoxicity, developmental toxicity, reproductive toxicity, immunotoxicity, and organ toxicity). Humans are at high risk of MPs uptake. Apart from aerial and soil contamination sources, consumption of aquatic food products is a critical pathway of MPs into the human body. MP toxicities in humans include liver disorder, respiratory failure, infertility, hormonal imbalance, diarrhea, developmental disorder, and mortal-ity. Measures to alleviate the effect of COVID-19 waste litters include effective waste management plans and the adoption of technologies to extract cum degrade MPs from the aquatic and terrestrial environment.
Interhemispheric Interaction and Saccadic Horizontal Eye Movements Implications for Episodic Memory, EMDR, and PTSD

and interhemispheric interaction is saccadic horizontal eye movements (EMs), which may induce statelike changes in both the accuracy of episodic memories and in the amount or quality of interhemispheric interaction. In this article, we examine the conceptual and empirical bases for the effects of saccadic horizontal EMs on memory and on inter-hemispheric interaction.
Al-Qadisiyah Journal of Pure Science Al-Qadisiyah Journal of Pure Science

The degradation of phenol by microorganisms in the soil is an important method through which these materials are removed from the environment, thus reducing environmental pollution. The aim of this study is to select and characterize bacterial strain(s) from oil contaminated soils and testing the ability for biodegradation of phenol. In this study, t wo Klebsiella oxytoca isolates were selected from petroleum contaminated soils using mineral salts medium supporting with phenol as the only carbon source. The isolates were identified by microscopic, morphological, and biochemical approaches , and their capability of biodegrading phenol was analyzed by 4-aminoantipyrine assay. The results showed that the selected Klebsiella oxytoca isolates were able to remove 100% of phenol even at the highest used concentration(500 mg / L). The results of the current study indicate the possibility of using Klebsiella oxytoca in bioremediation of phenol contaminated environments.
Prevalence and Severity of the Restless Leg Syndrome in Patients with Hip and Knee Osteoarthritis

Aim : To investigate Restless legs syndrome (RLS) if the prevalence, severity, pain levels, sleep hygiene and quality of life differs hip and knee osteoarthritis (OA). Material and Method : Between January, 2, 2020-June, 2, 2020, 103 patients with knee OA and 98 with hip OA between 55 and 75 years of age corresponding inclusion and exclusion criteria were recorded. The visual analog scale (VAS) for pain severity, the Lequesne severity index for the severity of OA, the Sleep Hygiene Indes for frequency and severity of RLS symptoms and sleep behaviors
A butterﬂy egg-killing hypersensitive response in Brassica nigra is controlled by a single locus, PEK, containing a cluster of TIR-NBS-LRR receptors

The hypersensitive response (HR) characterizes monogenic qualitative resistance traits in several pathosystems. Knowledge on its role in plant resistance to insects is so far limited to a few resistance ( R ) gene-based resistances against piercing-sucking insects. Egg deposition by cabbage white butterﬂies ( Pieris spp.), pests of cabbage crops ( Brassica spp.), can trigger an HR-like cell death, which reduces egg survival and represents an eﬀective plant resistance trait before feeding damage occurs. Here, we identiﬁed natural variation of HR-like to Pieris egg deposition in the black mustard ( B. nigra L.) and performed genetic mapping. HR-like segregated as a Mendelian trait and a single dominant locus on chromosome B3, named PEK ( P ieris e gg-k illing ) was identiﬁed. In the ˜50 kb region, eleven candidate genes, are located, including a cluster of genes encoding intracellular receptor proteins, TIR-NBS-LRR (TNLs). The PEK locus was found to be highly polymorphic between the parental accessions of our mapping populations and among B. nigra reference genomes. Our study is the ﬁrst that identiﬁes a single locus potentially involved in HR-like cell death induced by insect eggs. Further ﬁne-mapping, comparative genomics and validation of the PEK locus will shed light on the role of TNL receptors in egg-induced HR-like cell death.
UvA-DARE (Digital Academic Repository) Human milk From complex tailored nutrition to bioactive impact on child cognition and behavior

Human milk is a highly complex liquid food tailor-made to match an infant’s needs. Beyond documented positive effects of breastfeeding on infant and maternal health, there is increasing evidence that milk constituents also impact child neurodevelopment. Non-nutrient milk bioactives would contribute to the (long-term) development of child cognition and behavior, a process termed ‘Lactocrine Programming’. in this review we discuss the current state of the field on human milk composition and its links with child cognitive and behavioral development. To promote state-of-the-art methodologies and designs that facilitate data pooling and meta-analytic endeavors, we present detailed recommendations and best practices for future studies. Finally, we determine important scientific gaps that need to be filled to advance the field, and discuss innovative directions for future research. Unveiling the mechanisms underlying the links between human milk and child cognition and behavior will deepen our understanding of the broad functions of this complex liquid food, as well as provide necessary information for designing future interventions
Contributions to Depressed Affect in Latina Women: Examining the Effectiveness of the Moms’ Empowerment Program

Intimate partner violence (IPV) is a significant social and public health problem that includes physical violence, sexual violence, threats of physical or sexual violence, stalking, and psychological aggression by an intimate partner. Estimates suggest that 35% of Latinas living in the United States experience IPV in their lifetime, with known severe negative outcomes. One mental health consequence of concern is depression, which disproportionately affects IPV-exposed Latinas. The present study tested the effectiveness of the Moms’ Empowerment Program (MEP), a culturally adapted intervention to reduce depressive symptoms among IPV-exposed Spanish-speaking Latina mothers. Additional psychosocial predictors of levels of depressed affect over time are examined, including levels of post-traumatic stress, IPV exposure, positive parenting, parental acceptance of children’s negative emotions, and maternal employment. Participants (N = 72) were assigned to a treatment or a wait-list comparison condition, and those in the treatment group completed a 10-week group intervention addressing the unique problems associated with IPV exposure, mental health, and parenting among Spanish-speaking Latinas. Results of multilevel modeling revealed that participation in the MEP was associated with significant reductions in depressed affect. Lower levels of post-traumatic stress and higher levels of positive parenting, maternal acceptance of children’s negative emotions, and maternal employment predicted lower levels of depressed affect. The amount of total IPV exposure was not significantly associated with the extent of depressed affect. The MEP represents a culturally tailored, evidence-based intervention to reduce depressed affect among Spanish-speaking Latinas. The clinical implications of the additional predictors of levels of depressed affect are discussed.
Geochronology, geochemistry and tectonic implications of Weitingchagan composite pluton in northern segment of the Xing‐Meng Orogenic Belt

We undertook zircon U–Pb dating and geochemical analyses of the Weitingchagan (WT) pluton in the Dong Ujimqi area, Northeast China, with an aim of determining their ages, petrogenesis and sources, which are important for understanding the Late Palaeozoic tectonic evolution of the Xing‐Meng Orogenic Belt. The WT pluton consists of coarse‐ to medium‐grained porphyritic granites in the core and medium‐ to fine‐grained monzogranites in the rim, contains abundant microgranular enclaves and is intruded by small amounts of muscovite monzogranites. The results of LA‐ICP‐MS zircon U–Pb dating indicate that the WT composite pluton formed during the Late Carboniferous–Early Permian with the ages ranging from 289 Ma to 312 Ma. Petrological and geochemical characteristics of the WT pluton were derived from the partial melting of crustal materials, and the AFC process played an important role in the magmatic evolution. The porphyritic granites are I‐type granite, and the monzogranites and muscovite monzogranites are highly fractionated I‐type granite. Combined with previous studies on the contemporaneous magma‐tectonic activities in the Uliastai Continental Margin, the study suggests that the WT pluton formed in an extensional environment, which may relate to the closure of the Palaeo‐Asian Ocean. Copyright © 2016 John Wiley & Sons, Ltd.
From Searchers to Proposers: User Behaviour in Ethereum’s Proposer-Builder Separation

In September 2022, as the Ethereum blockchain shifted from a proof-of-work to a proof-of-stake consensus mechanism, the block generation process has undergone a remarkable transition with the widespread adoption of the Proposer-Builder Separation (PBS) mechanism. This separation allocates the roles of block building and block validation to distinct stakeholders (builders and proposers). Additionally, entities called relays act as intermediaries and connect builders to proposers. Finally, another key stakeholder, the searchers, try to capitalize on profit opportunities by dispatching transaction bundles to builders. This establishes a 3 tier layered structure (searchers, builders, and proposers), where each tier may optimize for maximum profit. In this study, we delve into the dynamics and interplay amongst the PBS market stakeholders and asses the current status of the PBS mechanism compared to its original objectives. Our findings reveal that both the relay and builder segment are characterized by an oligopolistic structure and are dominated by a handful of players. Further, we show that pro-posers consistently hold the largest profit share, followed by searchers and then builders. In contrast, a more granular analysis of individual players’ weekly profits suggests a potential disproportionate favoring towards builders as opposed to individual proposers and searchers. Additionally, we conceptualize the bidding auctions where builders compete against each other for their block to be chosen for chain inclusion. On one hand, our research suggests high potential for improvement of the builders’ bidding strategies and, on the other hand, reveals that notable percentage of builders use a reactive bidding strategy as opposed to bidding solely based on a block’s value.
Prognosis for Pediatric Patients with Isolated Atrial Septal Defect İzole Atriyal Septal Defektli Hastalarda Klinik Seyir ve Prognoz

of Children’s Health and Diseases between January 2003 and June 2008 who were 0–18 years of age, had echocardiographic examinations performed at least twice, and were followed-up for at least 6 months were included in the study. Results: The study population included 182 (46.9%) male and 206 (53.1%) female patients (female/male ratio: 1.13) with median age at diagnosis of 3 months (range: 1 month-17 years). In 189 patients (53.4%), ASD closed spontaneously. A total of 24 patients (6.8%) underwent surgery. In 43 patients (12.1%), defect was repaired using transcatheter procedure. At time of study, 98 patients (27.7%) were still under follow-up care. Early diagnosis and diameter of defect correlated with spontaneous closure (p<0.001). Conclusion: Age at diagnosis and size of defect are the most important criteria for clinical prognosis and spontaneous closure of defect in cases of ostium secundum ASD.
Electronic Health Record-Based Recruitment and Retention and Electronic Health Record-Based Recruitment and Retention and Mobile Health App Usage: Multisite Cohort Study. Mobile Health App Usage: Multisite Cohort Study.

Background: To address the obesity epidemic, there is a need for novel paradigms, including those that address the timing of eating and sleep in relation to circadian rhythms. Electronic health records (EHRs) are an efficient way to identify potentially eligible participants for health research studies. Mobile health (mHealth) apps offer available and convenient data collection of health behaviors, such as timing of eating and sleep. Objective: The aim of this descriptive analysis was to report on recruitment, retention, and app use from a 6-month cohort study using a mobile app called Daily24. Methods: Using an EHR query, adult patients from three health care systems in the PaTH clinical research network were identified as potentially eligible, invited electronically to participate, and instructed
Comparative study between transpedicular screws fixation with Comparative study between transpedicular screws fixation with and without interbody fusion using cages in lumbar and without interbody fusion using cages in lumbar spondylolisthesis spondylolisthesis

Background: lumbosacral spondylolisthesis is a common pathology characterized by single or multi-level slippage of lumbar vertebra over the other and may be associated with spinal canal stenosis and neural foramina compromization and may be presented by lower back pain, radicular pain, or neurogenic claudication pain. The current study aimed to compare the short-term clinical outcomes of two surgical fusion techniques in the management of this pathology. Aim of the study: Comparative study to evaluate outcome clinically and radiologically in cases of 1st and 2nd grade of degenerative lumbar spondylolisthesis treated with transpedicular fixation with or without interbody fusion by lumbar cage. Patients and Methods: 40 patients of lumbosacral spondylolisthesis were included in this study. Patients randomly divided into two groups according to the surgical approach and fixation technique used in the management. Group (A): operated by posterior lumbar decompression, transpedicular screw fixation and posterolateral intertransverse bony fusion. Group (B): operated by posterior decompression, transpedicular screw, posterolateral interbony fusion by insertion of interbody cages. Results: Statistical significance was reached in blood loss, and post-operative fusion rates, but there was no significant difference between the two groups regarding to intra-operative or post-operative complication rates, clinical outcome, and patient satisfaction. Conclusion: The application of the lumbar interbody cage with posterior lateral intertransverse fusion proved to have better fusion rates, but still intertransverse bony fusion alone gives the same results regarding patient satisfaction and post-operative clinical improvement with shorter operative time.
The Energy Retroﬁt Impact in Public Buildings: A Numerical Cross-Check Supported by Real Consumption Data

: In the framework of reducing carbon dioxide emissions and energy consumption, the energy retroﬁt of existing buildings plays a signiﬁcant role and is often supported by numerical analyses of the planned activities and expected results. This study analyses a public building (a kindergarten) located in Bialystok (Poland) and aims to determine the building’s energy performance prior to and after thermal modernization. The building was examined by employing two different software packages, Audytor OZC 7.0 Pro and Trnsys 18. The thermal efﬁciency improvement applied to the renovated building in Bialystok was also analyzed by virtually locating the building in Bologna (Italy). Moreover, a comfort analysis focused on the classrooms of the kindergarten was carried out employing Trnsys. As a novelty, in the analysis, particular attention is paid to ventilation losses and to the inﬂuence of envelope elements properties on the building energy demand. The results arising from analyses were compared to real consumption data for the heating season. The results obtained from the two software programs display excellent agreement, and they also match the real consumption data if the heating demand is considered, while some differences arise when the cooling demand is considered.