Miracle-dz/UniFAR-FTUs huggingface dataset:
Design Validation of a Multi-Stage Gradually Deploying Stent

Design Validation of a Multi-Stage Gradually Deploying Stent Dillon J. Despain Department of Mechanical Engineering, BYU Master of Science In-stent restenosis (ISR) induced by intimal hyperplasia is a common challenge to angioplasty, a common treatment for reopening narrowed vasculature via the use of rapidly deploying stents. High impact stresses from current stent deployment processes have been linked to intimal hyperplasia; thus, a stent that is gradually deployed over a longer period of time holds potential to mitigate these stresses. This work hypothesizes that resorbable polymeric links can be used as a triggering mechanism to enable repeatably controlled deployment of a compliant nitinol stent design with the eventual goal of reducing intimal hyperplasia. The aims of this work include the structured design process and design validation of such a stent. A structured design process was used to develop a multi-stage, gradually deploying nitinol stent in which PDLG (DL-lactide/Glycolide copolymer) bioresorbable links constrained specific mechanical cells within the stent geometry, thus limiting initial deployment to an intermediate diameter and allowing for secondary gradual deployment as the PDLG degraded via a combination of bioresorption and creep. A finite element analysis was carried out to design the link geometry to hold the stent at an intermediate stage (90% of final diameter) upon initial deployment, and enable a gradual secondary deployment phase lasting several minutes. Prototypes were then manufactured and the design was validated in a flow chamber mimicking the conditions of human blood flow and temperature. Using a camera and image processing methods, the diameter increase of the stents was tracked over time to characterize the secondary gradual deployment process of the stents. Results showed the links constrained the stents to an initial ~90% diameter upon initial deployment, followed by a gradual, secondary deployment with an average 63.2% rise time of 16.2 minutes. Creep was observed to be the primary driver of the gradual deployment, followed by subsequent bioresorption of the material. All prototypes exhibited gradual secondary deployment without any visible delamination of the bioresorbable links from the stent struts. Based on these findings it can be concluded our hypothesis has been demonstrated, and that a feasible gradually deploying stent design has been mechanically validated, preparatory to pre-clinical studies of its efficacy. Prior to clinical application, future in vivo work is needed to compare actual ISR rates with this stent design to other commonly used stent designs in preclinical trials. In addition, further preclinical work is needed to compare ISR rates through several stent design parameters such as initial deployment diameter, gradual deployment rate, final deployment diameter, and stent sizes to give insights into the optimal stent design. We anticipate that this gradually expanding stent design could reduce in-stent restenosis and improve clinical outcomes.
The tiny globulettes in the Carina nebula

Context. Small molecular cloudlets are abundant in many Hii regions surrounding newborn stellar clusters. In optical images these so-called globulettes appear as dark silhouettes against the bright nebular background. Aims. We aim to make an inventory of the population of globulettes in the Carina nebula complex, and to derive sizes and masses for comparisons with similar objects found in other Hii regions. Methods. The globulettes were identified from H images collected at the Hubble Space Telescope. Results. We have located close to 300 globulettes in the Carina complex, more than in any other region surveyed so far. The objects appear as well-confined dense clumps and, as a rule, lack thinner envelopes and tails. Objects with bright rims are in the minority, but more abundant than in other regions surveyed. Some globulettes are slightly elongated with their major axes oriented in the direction of young clusters in the complex. Many objects are quite isolated and reside at projected distances >1.5 pc from other molecular structures in the neighbourhood. No globulette coincides in position with recognized pre-main-sequence objects in the area. The objects are systematically much smaller, less massive, and much denser than those surveyed in other Hii regions. Practically all globulettes are of planetary mass, and most have masses less than one Jupiter mass. The average number densities exceed 10 5 cm 3 in several objects. We have found a statistical relation between density and radius (mass) in the sense that the smallest objects are also the densest. Conclusions. The population of small globulettes in Carina appears to represent a more advanced evolutionary state than those investigated in other Hii regions. The objects are subject to erosion in the intense radiation field, which would lead to a removal of any thinner envelope and an unveiling of the core, which becomes more compact with time. We discuss the possibility that the core may become gravitationally unstable, in which case free-floating planetary mass objects can form.
Various Interpretations of the Stored and the Radiated Energy Density

Three contradictory but state-of-the-art concepts for defining and evaluating stored electromagnetic energy are treated in this communication, and are collated with the widely accepted definition of stored energy, which is the total energy minus the radiated energy. All three concepts are compared, and the results are discussed on an example of a dominant spherical mode, which is known to yield dissimilar results for the concepts dealt with here. It is shown that various definitions of stored energy density immanently imply diverse meanings of the term "radiation".
Investor Relations, Corporate Governance and Internet Financial Reporting (IFR) Disclosure: Evidence from Companies Listed on Pakistan Stock Exchange (PSX)

Corporate governance is a system of rules and practices through which a business is directed and controlled. It also assists in balancing the interests of various corporate stakeholders. Earlier studies constructed certain instruments to achieve good corporate governance. In line with earlier studies, the main aim of the current study is to investigate the impact of investor relations and corporate governance on the internet financial reporting (IFR) disclosure. Quantitative data of the selected companies was analyzed. The results showed that ownership diffusion, type of auditor, firm size, and profitability of the firm have a positive and significant relationship with IFR, whereas institutional ownership and type of business activity are negatively associated with it. This study is useful for all types of stakeholders and specifically for policymakers, as well as for the academia.
Evaluating and minimizing distributed cavity phase errors in atomic clocks

We perform 3D finite element calculations of the fields in microwave cavities and analyse the distributed cavity phase (DCP) errors of atomic clocks that they produce. The fields of cylindrical cavities are treated as an azimuthal Fourier series. Each of the lowest components produces clock errors with unique characteristics that must be assessed to establish a clock's accuracy. We describe the errors and how to evaluate them. We prove that sharp structures in the cavity do not produce large frequency errors, even at moderately high powers, provided the atomic density varies slowly. We model the amplitude and phase imbalances of the feeds. For larger couplings, these can lead to increased phase errors. We show that phase imbalances produce a novel DCP error that depends on the cavity detuning. We also design improved cavities by optimizing the geometry and tuning the mode spectrum so that there are negligible phase variations, allowing this source of systematic error to be dramatically reduced.
Multiple scattering effects on inclusive particle production in the large-x regime

We study the multiple scattering effects on inclusive particle production in p+A and γ+A collisions. Specifically, we concentrate on the region where the parton momentum fraction in the nucleus x∼O(1) and incoherent multiple interactions are relevant. By taking into account both initial-state and final-state double scattering, we derive the nuclear size-enhanced power corrections to the differential cross section for single inclusive hadron production in p+A and γ+A reactions, and for prompt photon production in p+A reactions. We find that the final result can be written in a simple compact form in terms of four-parton correlation functions, in which the second-derivative, first-derivative and nonderivative terms of the correlation distributions share the same hard-scattering functions. We expect our result to be especially relevant for understanding the nuclear modification of particle production in the backward rapidity regions in p+A and e+A collisions.
Corporate Taxation and Evasion Responses: Evidence from a Minimum Tax in Honduras

We study corporate responses to a minimum income tax, using the universe of corporate tax filings in Honduras. The policy design allows us to separately estimate cost misreporting under profit taxation and the elasticity of reported revenue. Large corporations overreport true costs when taxed on profits. Taxing revenue leads to a substantial decrease in reported revenues: we estimate an elasticity in the range 0.35–1. The elasticity of revenue is attenuated when third-party information on the revenue of firms is available, suggesting misreporting plays an important role. Our results inform trade-offs when broadening tax bases to curb evasion. (JEL H25, H26, K34, L25, O14, O17)
Properties of dimension witnesses and their semidefinite programming relaxations

In this paper we develop a method for investigating semi-device-independent randomness expansion protocols that was introduced in [Li et al., Phys. Rev. A $\mathbf{87}$, 020302(R) (2013)]. This method allows to lower-bound, with semi-definite programming, the randomness obtained from random number generators based on dimension witnesses. We also investigate the robustness of some randomness expanders using this method. We show the role of an assumption about the trace of the measurement operators and a way to avoid it. The method is also generalized to systems of arbitrary dimension, and for a more general form of dimension witnesses, than it the previous paper. Finally, we introduce a procedure of dimension witness reduction, which can be used to obtain from an existing witness a new one with higher amount of certifiable randomness. The presented methods finds an application for experiments [Ahrens et al., Phys. Rev. Lett. $\mathbf{112}$, 140401 (2014)].
Advances in T Cells Based on Inflammation in Metabolic Diseases

With the increasing incidence of metabolic diseases year by year and their impact on the incidence of cardiovascular diseases, metabolic diseases have attracted great attention as a major health care problem, but there is still no effective treatment. Oxidative stress and inflammation are the main mechanisms leading to metabolic diseases. T cells are involved in the inflammatory response, which can also regulate the development of metabolic diseases, CD4+ T cells and CD8+ T cells are mainly responsible for the role. Th1 and Th17 differentiated from CD4+ T promote inflammation, while Th2 and Treg inhibit inflammation. CD8+ T cells also contribute to inflammation. The severity and duration of inflammatory reactions can also lead to different degrees of progression of metabolic diseases. Moreover, mTOR, PI3K-Akt, and AMPK signaling pathways play unique roles in the regulation of T cells, which provide a new direction for the treatment of metabolic diseases in the future. In this review, we will elaborate on the role of T cells in regulating inflammation in various metabolic diseases, the signaling pathways that regulate T cells in metabolic diseases, and the latest research progress.
A far-infrared survey at the North Galactic Pole – I. Nearby star-forming galaxies and effect of confused sources on source counts

We present follow-up observations of the far-infrared (FIR) sources at 90, 150 and 180 μm detected as part of the ISOPHOT EBL project, which has recently measured the absolute surface brightness of the cosmic infrared background (CIRB) radiation for the first time independently from COBE data. We have observed the fields at the North Galactic Pole region in the optical and near-IR, and complement these data with Sloan Digital Sky Survey photometry, and spectroscopy where available, and present identifications of the 25 FIR sources which reach down to ~ 150 mJy in all three ISOPHOT bands. Identifications are done by means of full spectral energy density fitting to all sources in the FIR error circle areas. Approximately 80 per cent are identified as star-forming or star-bursting galaxies at z < 0.3. We also find that more than half of the counterparts have disturbed morphologies, with signs of past or present interactions. However, only 20 per cent of all the sources are uniquely matched with a single galaxy -40 per cent are blends of two or more of these nearby star-forming galaxies, while another 20 per cent are likely blends of nearby and fainter galaxies. The final 20 per cent are likely to be more luminous IR galaxies at higher redshifts. The blended sources have an effect on the FIR source counts. In particular, taking into account realistic confusion or blending of sources, the differential FIR counts move down by a factor of ~ 1.5 and steepen in the 100 to 400 mJy range.
A CSP Field Theory with Helicity Correspondence

We propose the first covariant local action describing the propagation of a single free continuous-spin degree of freedom. The theory is simply formulated as a gauge theory in a "vector superspace", but can also be formulated in terms of a tower of symmetric tensor gauge fields. When the spin invariant $\rho$ vanishes, the helicity correspondence is manifest -- familiar gauge theory actions are recovered and couplings to conserved currents can easily be introduced. For non-zero $\rho$, a tower of tensor currents must be present, of which only the lowest rank is exactly conserved. A paucity of local gauge-invariant operators for non-zero $\rho$ suggests that the equations of motion in any interacting theory should be covariant, not invariant, under a generalization of the free theory's gauge symmetry.
The properties, origin and evolution of stellar clusters in galaxy simulations and observations

We investigate the properties and evolution of star particles in two simulations of isolated spiral galaxies, and two galaxies from cosmological simulations. Unlike previous numerical work, where typically each star particle represents one ‘cluster’, for the isolated galaxies we are able to model features we term ‘clusters’ with groups of particles. We compute the spatial distribution of stars with different ages, and cluster mass distributions, comparing our findings with observations including the recent LEGUS survey. We find that spiral structure tends to be present in older (100s Myrs) stars and clusters in the simulations compared to the observations. This likely reflects differences in the numbers of stars or clusters, the strength of spiral arms, and whether the clusters are allowed to evolve. Where we model clusters with multiple particles, we are able to study their evolution. The evolution of simulated clusters tends to follow that of their natal gas clouds. Massive, dense, long-lived clouds host massive clusters, whilst short-lived clouds host smaller clusters which readily disperse. Most clusters appear to disperse fairly quickly, in basic agreement with observational findings. We note that embedded clusters may be less inclined to disperse in simulations in a galactic environment with continuous accretion of gas onto the clouds than isolated clouds and correspondingly, massive young clusters which are no longer associated with gas tend not to occur in the simulations. Caveats of our models include that the cluster densities are lower than realistic clusters, and the simplistic implementation of stellar feedback.
The molecular clump towards the eastern border of SNR G18.8+0.3

The eastern border of the SNR G18.8+0.3, close to an HII regions complex, is a very interesting region to study the molecular gas that it is probably in contact with the SNR shock front. We observed the aforementioned region using the Atacama Submillimeter Telescope Experiment (ASTE) in the 12CO J=3-2, 13CO J=3-2, HCO+ J=4-3, and CS J=7-6 lines with an angular resolution of 22". To complement these observations, we analyzed IR, submillimeter and radio continuum archival data. In this work, we clearly show that the radio continuum "protrusion" that was early thought to belong to the SNR is an HII regions complex deeply embedded in a molecular clump. The new molecular observations reveal that this dense clump, belonging to an extended molecular cloud that surrounds the SNR southeast border, is not physically in contact with SNR G18.8+0.3, suggesting that the SNR shock front have not yet reached it or maybe they are located at different distances. We found some young stellar objects embedded in the molecular clump, suggesting that their formation should be approximately coeval with the SN explosion.
Reduce, reuse, recycle: Planetary nebulae as green galactic citizens

Abstract We review gas-phase abundances in PNe and describe their dual utility as archives of original progenitor metallicity via the α elements, as well as sources of processed material from nucleosynthesis during the star's evolution, i.e., C, N, and s-process elements. We describe the analysis of PN spectra to derive abundances and discuss the discrepancies that arise from different choices at each step. Abundance results for the Milky Way and Magellanic Clouds from various groups of investigators are presented; the observational results are compared with theoretical predictions of AGB stellar yields. Finally, we suggest areas where more work is needed to improve our abilities to determine abundances in PNe.
Spin-flipping with Holmium: case study of proximity effect in superconductor/ferromagnet/superconductor heterostructures

Superconductor/ferromagnet/superconductor heterostructures exhibit a so-called long-range proximity effect, provided some layers of conical magnet Holmium (Ho) are included in the respective interface regions. The Ho layers lead to a spin-flip process at the interface, generating equal-spin spin-triplet pairing correlations in the ferromagnet. These equal-spin spin-triplet pairing correlations penetrate much further into the heterostructure compared with the spin-singlet and unequal-spin spin-triplet correlations which occur in the absence of Ho. Here, we present calculations of this effect based on the spin-dependent microscopic Bogoliubovde Gennes equations solved within a tight-binding model in the clean limit. The influence of the ferromagnet and conical magnet layer thickness on the induced equal-spin spin-triplet pairing correlations is obtained and compared to available experimental data. It is shown that, in agreement with the experiment, a critical minimum thickness of conical magnet layers has to be present in order to observe a sizeable amount of equal-spin spin-triplet pairing correlations.
Examining The Fermi-LAT Third Source Catalog in search of dark matter subhalos

Dark matter annihilations taking place in nearby subhalos could appear as gamma-ray sources without detectable counterparts at other wavelengths. In this study, we consider the collection of unassociated gamma-ray sources reported by the Fermi Collaboration in an effort to identify the most promising dark matter subhalo candidates. While we identify 24 bright, high-latitude, non-variable sources with spectra that are consistent with being generated by the annihilations of ∼ 20–70 GeV dark matter particles (assuming annihilations to bb̄), it is not possible at this time to distinguish these sources from radio-faint gamma-ray pulsars. Deeper multi-wavelength observations will be essential to clarify the nature of these sources. It is notable that we do not find any such sources that are well fit by dark matter particles heavier than ∼100 GeV. We also study the angular distribution of the gamma-rays from this set of subhalo candidates, and find that the source 3FGL J2212.5+0703 prefers a spatially extended profile (of width ∼ 0.15°) over that of a point source, with a significance of 4. 2σ (3.6σ after trials factor). Although not yet definitive, this bright and high-latitude gamma-ray source is well fit as a nearby subhalo of mχ ≃ 20–50 GeV dark matter particles (annihilating to bb̄) and merits further multi-wavelength investigation. Based on the subhalo distribution predicted by numerical simulations, we derive constraints on the dark matter annihilation cross section that are competitive to those resulting from gamma-ray observations of dwarf spheroidal galaxies, the Galactic Center, and the extragalactic gamma-ray background.
Towards particle creation in a microwave cylindrical cavity

(DCE) radiation in a resonant cylindrical microwave cavity. Based on recent experimental proposals, we model an irradiated semiconducting diaphragm (SCD) using a time dependent ‘plasma sheet’ where we show that the number of photons created for the TM011 mode is considerably enhanced even for low laser powers (of J order). Conversely to the moving mirror case, we also show that the fundamental TM mode (TM010) is not excited for an irradiated plasma sheet. We show that polarization (arising due to the back reaction of pair created photons with the plasma SCD) implies losses for TM, but not TE modes. However, we argue that these losses can be reduced by lowering the laser power and shortening the relaxation time. The results presented here lead support to the idea that TE and, in particular, TM modes are well suited to the detection of DCE radiation in a cylindrical cavity.
Electrical tuning of Rashba spin-orbit interaction in multigated InAs nanowires

Indium arsenide nanowires (NWs) are a promising platform to fabricate quantum electronic devices, among other advantages they have strong spin-orbit interaction (SOI). The controlled tuning of the SOI is desired in spin-based quantum devices. In this study we investigate the possibility of tuning the SOI by electrostatic fields generated by a back gate and two side gates placed on the opposite sides of the NW. The strength of the SOI is analyzed by weak anti-localization effect. We demonstrate that the strength of the SOI can be strongly tuned up to a factor of 2 with the electric field across the NW, while the average electron density is kept constant. Furthermore, a simple electrostatic model is introduced to calculate the expected change of the SOI. Good agreement is found between the experimental results and the estimated Rashba-type SOI generated by the gate-induced electric field.