Miracle-dz/UniFAR-FTUs huggingface dataset:
Matching Building Energy Simulation Result against Measured Data with Weather File Compensation Factors

This paper describes a method to improve the accuracy of predicted space heating energy usage in existing buildings simulated using eQuest, an energy modeling program. The method is an adjustment of actual energy usage data using heating degree days (HDD) encoded in the inputted TMY weather file and short-term weather data collected on site. TMY weather files, in many cases, do not give an accurate representation of actual site temperatures around a building. An energy model that accurately reproduces energy use for an existing building under pre-retrofit conditions allows greater confidence in the predicted impacts and effects of any proposed changes. This is particularly valuable to stakeholders in the building industry, including contractors, consultants, owners, and managers. The method presented is simpler and less time-intensive than obtaining (if available) multiple years of hourly weather data or collecting those data on-site and then creating a custom TMY weather file. Rather this method normalizes the model output using a shorter period of on-site weather data. Results of this method in the example used improved the modeled energy usage to within -0.14% (95% CI: -0.98%, +0.68%) of metered energy usage. This approach to adjusting actual energy consumption data to the weather file offers a high level of confidence in the model’s accuracy, which is vital to design and economic decision-making.
A Web Model of Domestic Violence and Abuse in Muslim Communities—A Multi Perspective IPA Approach

This paper brings together two qualitative studies exploring how domestic violence and abuse (DVA) manifests within UK Muslim communities. Study one was conducted with UK-based Muslim female survivors of DVA (n = 10). Study two was conducted with UK professionals working in a supportive capacity with both DVA victims/survivors and those perpetrating abuse within Muslim communities (n = 9). Through a multi-perspective interpretative phenomenological lens, the two data sets were analysed for overarching themes. These themes were subsequently used to develop a graphical representation of the findings. The resulting outcome was the web model of DVA. The model identifies the trajectories and interactions at four levels in relation to DVA in Muslim communities. It is argued that this model has increased capacity for understanding the extended nature of how DVA manifests for UK Muslim communities, with a particular emphasis on the active role of faith and additional nuances often missed by singular methodological approaches. The model is recommended for use by services as a means toward individually tailored client care. Recommendations are made in relation to inclusive and decolonial approaches within gender-related violence research relating to minority communities in the UK.
Existence et unicité de solutions positives pour certaines équations elliptiques quasilinéaires

We show the uniquiness and we give necessary and sufficient conditions for the existence of positive solutions of the equation −Δ p u=f(x, u) where Δ p denotes the p-Laplacian and f(., r)/r p−1 is assumed to be decreasing On montre l'unicite et on donne des conditions necessaires et suffisantes pour l'existence de solutions positives de l'equation −Δ p u=f(x, u) ou Δ p est le p-laplacien et f(x, r) est telle que f(., r)/r p−1 est decroissante
Three-Dimensional Static Instability of Gravity Waves and a Possible Parameterization of the Associated Wave Breaking

Parameterizations of subgrid-scale gravity waves (GWs) in atmospheric models commonly involve the description of the dissipation of GWs. Where they dissipate, GWs have an increased effect on the large-scale flow. Instabilities that trigger wave breaking are an important starting point for the route to dissipation. Possible destabilizing mechanisms are numerous, but the classical vertical static instability is still regarded as a key indicator for the disposition to wave breaking. In this work, we investigate how the horizontal variations associated with a GW could alter the criterion for static instability. To this end, we use an extension of the common parcel displacement method. This three-dimensional static stability analysis predicts a significantly larger range of instability than does the vertical static stability analysis. In this case, the Lindzen-type saturation adjustment to a state of marginal stability is perhaps a less suitable ansatz for the parameterization of the GW breaking. In order to develop a possible ansatz for the GW dissipation due to three-dimensional instability, we apply the methods of irreversible thermodynamics, which are embedded in the Gibbs formalism of dynamics. In this way, the parameterization does not only satisfy the second law of thermodynamics, but it can also be made consistent with the conservation of energy and further (non-)conservation principles. We develop the parameterization for a discrete spectrum of GW packets. Offline computations of GW drag and dissipative heating rates are performed for two vertical profiles of zonal wind and temperature for summer and winter conditions from CIRA data. The results are compared to benchmarks from the literature.
Collaborative turn construction in paired speaking tests across different proficiency levels

ABSTRACT To be able to assess interactional competence (IC), which believed to be shared knowledge rather than an individual skill, talk in paired speaking tests can be analyzed. Accordingly, this study investigates how L2 speakers of English collaboratively construct turns in paired speaking tests mainly through embodied word search sequences and their relation to IC based on a dataset of 48 recorded paired speaking tests collected from a state university in Turkey. Results of the study have revealed that turn completion is mostly constructed at word level but also at sentence level for some cases. It is shown that collaborative turn construction practices vary across different proficiency levels, especially between B1 and B2. In addition to this, there are six different resources employed by interactants to receive turn completion and the higher the students’ proficiency level is, the more varied the resources they use to do so. It is also revealed that interactants almost always achieve mutual understanding following a turn completion. Findings of the study can feed into L2 assessment practices and pedagogical practices in L2 classrooms in a way that can facilitate the teaching of L2 IC.
Correlations Between Characteristics of Mean Light Curves of Long Period Variables

The light curves of sixty-two Mira-type variables best covered by AAVSO observations made between 1974 and 1977 (AAVSO 1983) were approximated by a trigonometric polynomial fit with optimal values of the number of harmonics and of the period. Correlations between the pairs of twenty-five parameters are discussed.
Une extension de l'analyse canonique. Quelques applications

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Ethnobotanical and Socio-economic Value of Blighia sapida (K.D. Koenig) in Togo

Aims: In Africa, and particularly in Togo, fruit trees occupy a special place because of their medicinal and food virtues,. This study aimed to identify the different uses of Blighia sapida in Togo. Methodology: investigations were conducted among 300 B. sapida users in nine villages in the prefectures of Tône, Kozah and Haho of Togo. The choice of the study area was based on its representativeness in relation to the geographical distribution of B. sapida; the presence of resource persons with endogenous knowledge, and the existence of markets where B. sapida organs and fruits are traded. Data collection phase took place in households and markets. The questionnaire solicited information on the socio-demographic characteristics of the respondents; the use of this plant species by the populations, the routes of administration or formulations as well as the quantity sold per day. Results: Blighia sapida is used for nutritional, therapeutic and cosmetic purposes with the main route of administration being oral. Respondents were predominantly female over 55 years of age. The supply of the fruits of this plant is by purchase and the average amount sold daily is 2500 F (≈4 €). Conclusion: This study showed that various organs of B. sapida are used by the communities. It is a first step towards the valorization of plant resources.
Does the Number of Levels of Decompression Have an Impact on the Clinical Outcomes of Patients With Lumbar Degenerative Spondylolisthesis: A Retrospective Study in Single-Level Fused Patients

Introduction The American Association of Neurological Surgeons (AANS) and the Congress of Neurological Surgeons (CNS) 2014 lumbar fusion guidelines for stenosis with degenerative spondylolisthesis (DS) support surgical decompression and fusion as an effective treatment option for symptomatic stenosis associated with DS. The association between the number of levels decompressed in patients with single-level fusion and clinical outcomes has never been published. Methods A retrospective analysis of a single-center, prospectively collected database was performed on 77 patients to compare the effect of the number of decompression levels in patients that received single-level fusion surgery. A total of 77 patients met the criteria. Group one had one level decompressed, group two had two levels decompressed, and group three had three or four levels decompressed. All patients received lumbar fusion surgery at a single spinal level. Outcomes at six months included: Substantial Clinical Benefit (SCB) (ΔODI ≥ 10 points); Minimal Clinically Important Difference (MCID) (ΔODI ≥ 5); no MCID (ΔODI <5 points). Student's t-tests, one-way analysis of variance (ANOVA), and post hoc comparison using unpaired two-tailed student's t-test with Holm-Bonferroni correction were performed. p -values were ranked from smallest to largest, and alpha level adjustments were made. Results A sub-analysis of each group's clinical outcomes showed that patients with two levels decompressed reached greater clinical outcomes. SCB was obtained by approximately 60% (group one: 12.5% vs. group three: 40%) of the patients. A total of 77.6% (38/49) achieved MCID (group one: 62.5% vs. group three: 55%). Single-level fused patients with two levels of decompression showed an improvement of 48% from baseline ODI, as opposed to group one: 17.85% and group three: 21.1%. Patients belonging to group two showed the lowest rate of no improvement. Baseline ODI scores were similar upon presentation (p=0.46), and the difference was found among groups after six months of follow-up (p=0.009). Post hoc comparison showed statistical significance in the comparison between group two and group three (p=0.009, alpha value: 0.017). Conclusion The addition of more than two levels of decompression to single-level fused patients might be associated with poor clinical outcomes and spinal instability.
Practical needs of oral prosthodontics in the field of health

Reason: Teeth, related to chewing, aesthetics and vocal function, are an essential element. Therefore, the absence of teeth is considered to lead to the deterioration of oral health. Objective: To determine the actual needs of oral restoration in the Northern Health District of camagui city. Methods: A cross-sectional descriptive study was conducted on the population in the Northern Health District of camagui city from October 2013 to April 2015. The study included 574 men and women aged 18 and over.Results: Female patients over 60 years old were dominant. Of the 574 people examined, 401 were determined to need artificial rehabilitation, and tooth loss was the main reason. People over the age of 60 have the greatest actual demand for prosthetics. With regard to gender, it was noted that women needed some prosthetic treatment because it was higher than men. Conclusion: The actual demand for oral restoration in female patients over 60 years old is widespread, and the main reason is the loss of teeth.
Acceptability and feasibility of a multidomain harmonized data collection protocol in youth mental health

To develop targeted treatment for young people experiencing mental illness, a better understanding of the biological, psychological, and social changes is required, particularly during the early stages of illness. To do this, large datasets need to be collected using standardized methods. A harmonized data collection protocol was tested in a youth mental health research setting to determine its acceptability and feasibility.
-Omic Approaches and Treatment Response in Rheumatoid Arthritis

Rheumatoid arthritis (RA) is an inflammatory disorder characterized by an aberrant activation of innate and adaptive immune cells. There are different drugs used for the management of RA, including disease-modifying antirheumatic drugs (DMARDs). However, a significant percentage of RA patients do not initially respond to DMARDs. This interindividual variation in drug response is caused by a combination of environmental, genetic and epigenetic factors. In this sense, recent -omic studies have evidenced different molecular signatures involved in this lack of response. The aim of this review is to provide an updated overview of the potential role of -omic approaches, specifically genomics, epigenomics, transcriptomics, and proteomics, to identify molecular biomarkers to predict the clinical efficacy of therapies currently used in this disorder. Despite the great effort carried out in recent years, to date, there are still no validated biomarkers of response to the drugs currently used in RA. -Omic studies have evidenced significant differences in the molecular profiles associated with treatment response for the different drugs used in RA as well as for different cell types. Therefore, global and cell type-specific -omic studies analyzing response to the complete therapeutical arsenal used in RA, including less studied therapies, such as sarilumab and JAK inhibitors, are greatly needed.
The Intracluster Medium: An Invariant Stellar Initial Mass Function

Evidence supporting the hypothesis of an invariant stellar initial mass function (IMF) is strong and varied. The intracluster medium (ICM) in rich clusters of galaxies is one of the few contrary locations where recent interpretations of the chemical abundances have favored an IMF that is biased toward massive stars, compared with the "normal" IMF. This interpretation hinges upon the neglect of Type Ia supernovae toward the ICM enrichment, and a particular choice of the nucleosynthesis yields of Type II supernovae. We demonstrate here that when one adopts yields determined empirically from observations of Galactic stars, rather than the uncertain model yields, a self-consistent picture may be obtained with an invariant stellar IMF and about half of the iron in the ICM being produced by Type Ia supernovae.
Estrogen Receptor 1 (ESR1) and the Wnt/β-Catenin Pathway Mediate the Effect of the Coumarin Derivative Umbelliferon on Bone Mineralization

Bone physiology is regulated by osteoblast and osteoclast activities, both involved in the bone remodeling process, through deposition and resorption mechanisms, respectively. The imbalance between these two phenomena contributes to the onset of bone diseases. Among these, osteoporosis is the most common metabolic bone disorder. The therapies currently used for its treatment include antiresorptive and anabolic agents associated with side effects. Therefore, alternative therapeutic approaches, including natural molecules such as coumarin and their derivatives, have recently shown positive results. Thus, our proposal was to investigate the effect of the coumarin derivative umbelliferon (UF) using an interesting model of human osteoblasts (hOBs) isolated from osteoporotic patients. UF significantly improved the activity of osteoporotic-patient-derived hOBs via estrogen receptor 1 (ESR1) and the downstream activation of β-catenin pathway. Additionally, hOBs were co-cultured in microgravity with human osteoclasts (hOCs) using a 3D system bioreactor, able to reproduce the bone remodeling unit in bone loss conditions in vitro. Notably, UF exerted its anabolic role by reducing the multinucleated cells. Overall, our study confirms the potential efficacy of UF in bone health, and identified, for the first time, a prospective alternative natural compound useful to prevent/treat bone loss diseases such as osteoporosis.
Phaseolus vulgaris Erythroagglutinin (PHA-E)-Positive Ceruloplasmin Acts as a Potential Biomarker in Pancreatic Cancer Diagnosis

Pancreatic cancer (PC) remains one of the top 10 causes of cancer-related death in recent years. Approximately 80% of PC patients are diagnosed at the middle or advanced stage and miss the opportunity for surgery. The demand for early diagnostic methods and reliable biomarkers is increasing, although a number of tumor markers such as CA19-9 and CEA have already been utilized in clinics. In this study, we analyzed the alteration of N-glycan of serum glycoproteins by mass spectrometry and lectin blotting. The results showed that bisecting GlcNAc structures of glycoproteins are significantly increased in PC patients’ sera. With Phaseolus vulgaris Erythroagglutinin (PHA-E) lectin that specifically recognizes bisecting GlcNAc N-glycans, the serum glycoproteins bearing bisecting GlcNAc in PC patients’ sera were pulled down and identified by nano-LC-MS/MS. Among them, ceruloplasmin (Cp) was screened out with a satisfied sensitivity and specificity in identifying PC from acute pancreatitis patients (AUC: 0.757) and normal healthy persons (AUC: 0.972), suggesting a close association between Cp and PC development and diagnosis. To prove that, the Cp expression in tumor tissues of PC patients was examined. The results showed that Cp was significantly upregulated in PC tissues compared to that in adjacent normal tissues. All these results suggested that PHA-E-positive Cp could be a potential PC-specific glycoprotein marker to distinguish PC patients from acute pancreatitis patients and normal persons.
Parental Partnership, Advocacy and Engagement: The Way Forward

This article, written with parents as co-authors, has two aims: (1) to provide a critical view of the English child protection system based on parents’ views and to locate these views within contemporary child protection studies and (2) to present the transformative value of co-production in the context of child protection studies both as a form of critical scholarship and as a means to influence policy and practice. The current children’s social work system in England does not achieve good outcomes for families, and many children and parents frequently experience it as stigmatizing, inhumane, and harmful. The article presents the experience and recommendations for change produced by parents with a broad range of experience with child protection services in England. The Parents, Families and Allies Network worked with five allied organizations in which parents identified the extensive range of problems that the current system presents and ways forward to achieve more supportive, humane, and inclusive practice with families. Seven main themes emerged: a better definition of need and response to need; partnership, participation, and humane practice; improving legal representation and support in legal proceedings; better support in care proceedings; permanence that maintains links; a better response to domestic violence; and the lack of support for disabled children. The article discusses five features of the project that supported meaningful co-production: taking a political stance, choosing clear and feasible aims, incorporating a range of knowledge, the participation of parents with lived experience throughout all phases of the project, and not settling with just knowledge production.
Risk Factors of Parkinson’s Disease: A Case-Control Study in Moroccan Patients

Background: Parkinson’s disease (PD) remains a significant health concern in Morocco. Multivariate analysis was not used in any study to evaluate the role of various factors that contributed to the onset of the disease. Objectives: This study investigates the role of family, environmental, and professional factors in PD development. Methods: The present study is an age-matched case-control study with risk estimation based on odds ratios (OR) with a 95% confidence interval (CI). In total, 180 cases were matched with 360 controls. Results: The average age of participants was 68.3 ± 11.2 years. Adjusted logistic regression analysis showed that the family history of PD (ORa = 7.19, CI 95% 3.41 - 15.13), male sex (ORa = 1.92, CI 95% 1.16 - 3.16), spring water consumption (ORa = 3.31, CI 95% 2.05 - 5.34), drug use (ORa = 2.12, CI 95% 1.33 - 3.38), a history of head injury (ORa = 3.38, CI 95% 1.16 - 9.83) and non - consumption of coffee (ORa = 3.04, CI 95%1.56 - 5.90) were significantly associated with the onset of the disease. In a univariate analysis, well water consumption was observed as a significant risk factor but could not be shown to be significant in a multivariate analysis. Previous work on a farm (ORa = 0.30, CI 95% 0.16 - 0.54) and history of general anesthesia (ORa = 0.47, CI 95% 0.27 - 0.83) were inversely associated with PD risk. No statistical significance was observed in the data on occupational exposure and disease risk, although there was a 30% decrease in risk for the service occupations (ORa = 0.05, CI 95% 0.01 - 0.18). Conclusions: As a result, further research is needed to determine additional risk factors.
Impact of COVID-19 on wood-based products industry: An exploratory study in Slovenia, Croatia, Serbia, and BiH

ABSTRACT The COVID-19 pandemic has significantly impacted the forest-products industry locally and globally, including the availability of raw materials, supply chain, production, and product sales. Therefore, it was essential to study the effect of COVID-19 in Central and Southeast European countries, including Slovenia, Croatia, Serbia, and Bosnia and Herzegovina, where the forest-products industry plays a vital global role. An international group of wood scientists developed and implemented the web-based questionnaire that consisted of four parts: demographic questions, production changes, COVID data gathering, governmental response to COVID-19, and lessons learned. Participants were mainly from furniture production, joinery, and wood processing. Results indicate that more than 80% of respondents reported negative changes. The COVID-19 pandemic has seriously affected the supply chain, and the most significant changes were in the availability of solid wood (23%) and engineered wood products (21%). Among the most critical issues were increased prices of all materials, increased transportation costs, extended delivery times, limited quantities for all materials, and total disruption of supply chains.