Miracle-dz/UniFAR-FTUs huggingface dataset:
Automatic variable selection in a linear model on massive data

Abstract For a linear model on massive data, we propose an aggregated estimator depending on adaptive LASSO estimators. The proposed method allows the reduction of the data storage volume and the introduction of an aggregates estimator which automatically selects, with a probability converging to one, the significant explanatory variables. Moreover, the aggregated estimator, corresponding to the non null true parameters has the same asymptotic Normal law as the adaptive LASSO estimator on the all data. But, the estimator calculated on all data is practically impossible to calculate, for lack of calculation memory or storage, when the model is on massive data. Then, another interest of our method is that it can work around the data processing problem of insufficient memory allocated by statistical software when the observation number is very large. The empirical performance is investigated by a comparative simulation study. A real data example is used to illustrate the usefulness of our method.
How is Students’ Motivation Enhanced in English Classrooms in Unstable Socio-political Contexts?

In a situation where life is insecure and the future seems to hang by a thread, motivating students to learn a second language that has no immediate need in their daily lives could be challenging. This article explores the motivation to learn English as a second language of students and the use of motivational strategies of English teachers in one state of Myanmar, which has undergone civil wars for more than seventy years. Sequential explanatory mixed-method research was employed to investigate this complex phenomenon. Questionnaires, classroom observations, and semi-structured interviews were used to collect the data. A pleasantly surprised finding showed that the students could still remain a certain level of motivation to learn English amidst great hardship and fear in everyday life. As for the teachers’ motivational strategies, most that were observed and reported did not tend to support students’ autonomy. The findings lend support to previous studies on the effects of unstable sociopolitical situations on students and teachers and highlight the needs for effective teacher trainings for pre-service and in-service teachers in such areas.
Tonal specification of speaker commitment in Salerno Italian wh-questions

The paper addresses the issue of variability in the mapping between intonation and meaning in Salerno Italian. The general hypothesis tested is that variation of both the phonological and phonetic levels of intonation reflects speaker’s commitment to the proposition expressed. Here we report an investigation of the intonational meaning in wh-questions in Salerno Italian. Results show that both nuclear pitch accent type and its relative pitch excursion are crucial cues to differentiate between information-seeking and echo wh-questions. Results are interpreted as indicating the presence vs absence of speaker commitment to a salient proposition evoked by the wh-question. Boundary choice, on the other hand, appears to be dependent on speaker specific strategies. Hence, results call for the need of an intonational meaning model that takes into account individual variability.
An investigation of environmental factors influencing quantitative accuracy and recognition rate of craniofacial reconstructions

Six craniofacial reconstructions were produced using three-dimensional modeling software from 3D skull images of live Korean adult subjects generated by cone-beam computerized tomography. The six craniofacial reconstructions were divided into two groups: three created using an outdated Korean averaged facial soft tissue thickness dataset, and three created using a recent one. The accuracies for six craniofacial reconstructions were measured using face-pool comparison and geometric surface comparison methods to estimate the influential level of average facial soft tissue depth datasets to craniofacial reconstructions.
Demonstrating detail in investigative interviews—An examination of the
 DeMo
 technique

Correspondence Joris Heinsbroek, Institute of Criminal Justice Studies, University of Portsmouth, St George's building, 141 High Street, Portsmouth PO1 2HY, UK. Email: jorisheinsbroek@gmail.com Summary Attaining an uninterrupted free report (FR) is at the heart of best practice investigative interviewing guidance. However, witnesses/victims do not naturally provide detailed accounts. Techniques have been developed to counter-act this, such as a report everything (RE) instruction. This research examined the relative effectiveness of an addition to the RE component, a demonstration of the level of detail, using a behavioural exemplar, by describing an innocuous object; the Demonstration for More detail (DeMo) technique. Participants (N = 61) watched a mock crime video and asked to recall it using one of three instructions: (a) basic FR as the control, (b) RE instruction and (c) RE instruction plus DeMo technique. Participants who were given the DeMo technique recalled more details than both the control and RE groups. Accuracy rates were similarly high across all conditions. The implications of using the DeMo technique within an investigative interview are discussed.
Towards Computationally Efficient and Realtime Distracted Driver Detection With MobileVGG Network

According to the World Health Organization (WHO) report, the number of road traffic deaths have been continuously increasing since last few years though the rate of deaths relative to world's population has stabilized in recent years. As per the survey of National Highway Traffic Safety Administration (NHTSA), distracted driving is a leading factor in road accidents. In this paper, we present a Convolutional Neural Network (CNN) based approach for detecting and classifying the driver distraction. In the development of safety features for Advanced Driver Assistance Systems, the algorithm not only has to be accurate but also efficient in terms of memory and speed. Hence, we focused on developing computationally efficient CNN while maintaining good accuracy. We propose a new architecture named as mobileVGG based on depthwise separable convolutions. We evaluate results of the proposed network on the American University in Cairo (AUC) distracted driver detection dataset as well as Statefarm's dataset on Kaggle and compare the performance with state-of-the-art CNN architectures from literature. Our proposed mobileVGG architecture with just 2.2M parameters outperforms earlier approaches while achieving 95.24% and 99.75% accuracy on AUC and Statefarm's dataset respectively with less computational complexity and memory requirement.
Immunogenicity of Immunotoxins Containing Pseudomonas Exotoxin A: Causes, Consequences, and Mitigation

Immunotoxins are cytolytic fusion proteins developed for cancer therapy, composed of an antibody fragment that binds to a cancer cell and a protein toxin fragment that kills the cell. Pseudomonas exotoxin A (PE) is a potent toxin that is used for the killing moiety in many immunotoxins. Moxetumomab Pasudotox (Lumoxiti) contains an anti-CD22 Fv and a 38 kDa portion of PE. Lumoxiti was discovered in the Laboratory of Molecular Biology at the U.S. National Cancer Institute and co-developed with Medimmune/AstraZeneca to treat hairy cell leukemia. In 2018 Lumoxiti was approved by the US Food and Drug Administration for the treatment of drug-resistant Hairy Cell Leukemia. Due to the bacterial origin of the killing moiety, immunotoxins containing PE are highly immunogenic in patients with normal immune systems, but less immunogenic in patients with hematologic malignancies, whose immune systems are often compromised. LMB-100 is a de-immunized variant of the toxin with a humanized antibody that targets mesothelin and a PE toxin that was rationally designed for diminished reactivity with antibodies and B cell receptors. It is now being evaluated in clinical trials for the treatment of mesothelioma and pancreatic cancer and is showing somewhat diminished immunogenicity compared to its un modified parental counterpart. Here we review the immunogenicity of the original and de-immunized PE immunotoxins in mice and patients, the development of anti-drug antibodies (ADAs), their impact on drug availability and their effect on clinical efficacy. Efforts to mitigate the immunogenicity of immunotoxins and its impact on immunogenicity will be described including rational design to identify, remove, or suppress B cell or T cell epitopes, and combination of immunotoxins with immune modulating drugs.
Annual Precipitation Affects Reproduction of the Southern Grey Shrike (Lanius meridionalis)

Abstract We studied the breeding ecology of the Southern Grey Shrike (Lanius meridionalis) at the Shezaf Nature Reserve, Arava Valley, Israel, an extremely arid desert with mean annual rainfall of 30 mm. We color-banded 128 shrikes during 2007–2009. The breeding season lasted from late February until late June. We found 34 nests and a correlation between years with amount of precipitation and number of breeding pairs. Second broods after successful broods were found only in 2007 and were all unsuccessful. Most nests were in Acacia trees; pairs that nested in dry trees, lacking foliage, were more likely to fail. The average clutch size was 3.44; average number of nestlings was 1.95; and average number of nestlings that fledged was 1.24. These results are lower than other studies of the species, probably a result of the scarcity of food in the arid environment. Nest survival rate was higher during incubation than during rearing of nestlings (0.71vs. 0.62), and total nest survival was 44.5%. The arid Arava Valley influences breeding success of Southern Grey Shrikes, and the present severe drought could negatively influence persistence of the shrike population in the Arava Valley.
Language Teacher Identity Construction of Foreign Language Teaching Assistants.

Language teacher identity has been studied in several contexts in English Language Teaching (ELT) field; however, looking at language teacher identity in a United States context in which teachers from other countries teach their native languages as a foreign language has been a rare topic so far. Therefore, this phenomenological qualitative study investigated the lived experiences of four foreign language teaching assistants who lived and taught in the United States through Fulbright Foreign Language Teaching Assistant (FLTA) Program. The findings indicated four main emerging themes: (a) pedagogical shift, (b) crosscultural awareness, (c) challenges, and (d) goals and expectations. These dynamic components shaped language teachers’ identity in this context. The results are presented under the framework of language teacher identity. Implications as a guide for future FLTA teachers and for teacher exchange programs are provided.
A Survey of Woody Tropical Species for Boron Retranslocation

Abstract The mobility in phloem of boron (B) has been reported to vary among plant species. Boron is phloem immobile in many species and completely mobile in others. Recent reports regarding phloem B mobility or immobility only considered temperate plants, and there is no information on tropical species. Information of phloem B mobility is useful for improving the diagnosis of B deficiency and management of B status in crop production. This study aimed to survey tropical species for their B mobility. Leaf samples of 17 species, including cashew (Anacardium occidentale L.), mango (Mangifera indica L.), custard apple (Annona squamosa L.), papaya (Carica papaya L.), cassava (Manihot esculenta Crantz.), Indian walnut (Samanea samen (Jacq.) Marrill. ), cork wood tree (Sesbania grandiflora (L.) Pers. ), tamarind (Tamarindus indica L.), jackfruit (Artocarpus heterophyllus Lamk.), guava (Psidium guajava L.), star fruit (Averrhoa carambola L.), passion fruit (Passiflora edulis Sims.), coffee (Coffea arabica L.), lime (Citrus aurantifolia Swingle.), longan (Euphoria longana Lam.), lychee (Lychi chinensis Sonn.) and teak (Tectona grandis L.) were collected in the position of the youngest fully expanded leaf (YFEL), the middle leaf age of a branch (ML) and the oldest leaf (OL). Based on a premise that the nutrient concentration gradient between young and old leaves will be steeper in those species in which B is immobile, B concentration in the different leaf positions was examined in comparison with calcium (Ca is phloem immobile) and potassium (K is phloem mobile). Concentrations of K in all leaf types were not significantly different or decreased with leaf age, while Ca concentrations were always higher in the older leaves. Three species; tamarind, guava and teak, showed concentration gradients of B that were similar to K. The results suggested that B may be retranslocated from older to younger leaves of these species, hence indicating that B may be phloem mobile in these species. However, this hypothesis needs confirmation through studies examining retranslocation of B using 10B isotope or identification of B-complexing molecules in the phloem, e.g. sugar alcohols.
Emerging Antineoplastic Biogenic Gold Nanomaterials for Breast Cancer Therapeutics: A Systematic Review

Abstract Breast cancer remains as a concerning global health issue, being the second leading cause of cancer deaths among women in the United States (US) in 2019. Therefore, there is an urgent and substantial need to explore novel strategies to combat breast cancer. A potential solution may come from the use of cancer nanotechnology, an innovative field of study which investigates the potential of nanomaterials for cancer diagnosis, therapy, and theranostic applications. Consequently, the theranostic functionality of cancer nanotechnology has been gaining much attention between scientists during the past few years and is growing exponentially. The use of biosynthesized gold nanoparticles (AuNPs) has been explored as an efficient mechanism for the treatment of breast cancer. The present study supposed a global systematic review to evaluate the effectiveness of biogenic AuNPs for the treatment of breast cancer and their anticancer molecular mechanisms through in vitro studies. Online electronic databases, including Cochrane, PubMed, Scopus, Web of Science, Science Direct, ProQuest, and Embase, were searched for the articles published up to July 16, 2019. Our findings revealed that plant-mediated synthesis was the most common approach for the generation of AuNPs. Most of the studies reported spherical or nearly spherical﻿-shaped AuNPs with a mean diameter less than 100 nm in size. A significantly larger cytotoxicity was observed when the biogenic AuNPs were tested towards breast cancer cells compared to healthy cells. Moreover, biogenic AuNPs demonstrated significant synergistic activity in combination with other anticancer drugs through in vitro studies. Although we provided strong and comprehensive preliminary in vitro data, further in vivo investigations are required to show the reliability and efficacy of these NPs in animal models.
Structure and ecology of epiphyte communities of a cloud forest in central Veracruz, Mexico

Abstract. 39 species of vascular epiphytes were found in a 625-m2 plot in a cloud forest in Veracruz, Mexico. Epiphyte biomass was estimated for all species in six zones distinguished on each tree > 10 cm in DBH: stem base, lower stem, upper stem, branches > 20 cm, branches from 5 — 20 cm and branches < 5 cm diameter. Branches were additionally separated according to their position in the upper, middle or lower canopy. Total dry matter of green organs was 318 kg/ha. Dominance/diversity curves fitted best to the lognormal model. Principal Coordinate Analysis showed that canopy height and branch thickness are both important factors and also that the stem base was the most distinct zone. Microhabitat preferences and niche overlap of the frequent species proved some degree of resource partitioning within the canopy. Ecophysiological characters possibly responsible for these preferences and implications for conservation are discussed.
Review of cold water pollution in the Murray–Darling Basin and the impacts on fish communities

Summary The release of water from deep below the surface of large dams causes significant disturbance to water temperature regimes in downstream river channels with consequent impacts upon aquatic biota and river health. The Murray–Darling Basin (MDB) has a large number of dams, which are known to cause cold water pollution (CWP) in the downstream reaches of the impounded rivers. This study reviews the situation with regard to CWP in the MDB including the location, magnitude and extent of temperature suppression, the impacts upon fish, constraints and progress towards ameliorating the problem.
Investigating Factors Affecting Intention to Use Mobile Payment Among Young Professionals in Malaysia

This paper is to investigate the factors that influence intention to use of mobile payment among young professionals in Malaysia. Theory acceptance model and Theory of planned behavior had been integrated to investigate this phenomenon. Five factors (perceived ease of use, perceived usefulness, attitude, subjective norms, perceived behavioral control) were tested on intention to use mobile payment. In addition, trust was added to the framework as moderator. Data were distributed to a total of 250 young professional via online survey. After screening the returned questionnaires, a total of 211 questionnaires were acceptable and continued for further analysis. The finding shows that attitude and perceived behavioral control have a positive and significant relationship toward intention to use of mobile payment among young professionals. Whereas, subjective norm, perceived ease of use and perceived usefulness were found to be insignificant. Meanwhile, trust moderates the relationship between attitude and subjective norms toward intention to use mobile payment. The results from this study could help to inform marketers and mobile payment service providers about the significant factors that influence intention to use of mobile payment, so they can adapt their marketing strategies to suit the needs and wants of young professional in Malaysia.
Applications of Fuzzy Logic to Reconfigure Human Resource Management Practices for Promoting Product Innovation in Formal and Non-Formal R&D Firms

Human resource management (HRM) practices for promoting innovation tend to vary from one context to another. This leads us to investigate the configurations of internal HRM practices and supply chain collaborations that help firms to achieve high levels of product innovation or cause firms to achieve low levels of product innovation in formal R&D firms—firms which have actively engaged in systematic innovation, have established an R&D department, and/or have allocated budgets for R&D intention—and non-formal R&D firms. The data were collected during the period December 2016–February 2017 from manufacturing firms located in the Bangkok metropolitan area, Thailand. In total, 87 respondents were included for an empirical fuzzy-set qualitative comparative analysis. The results indicate that, first, formal and non-formal R&D firms achieve high levels of product innovation by adopting internal HRM practices or collaborating with customers/suppliers. They also can achieve high levels of product innovation if they adopt both simultaneously. Second, formal R&D firms achieve high levels of product innovation if they adopt R&D personnel development; otherwise, they need to collaborate with customers and suppliers to achieve high levels of product innovation. Finally, miss-adopting R&D personnel development causes formal and non-formal firms to achieve lows levels of product innovation.
The role of customer intimacy in increasing Islamic bank customer loyalty in using e-banking and m-banking

Purpose The purposes of this study are to develop an extended technology acceptance model (TAM) model by adding customer intimacy, perceived risk, trust and Sharia compliance as external variables, in which TAM is used as the evaluation method for the use of e-banking and m-banking by customers of Islamic bank; and to study the role of customer intimacy in increasing satisfaction and encouraging loyalty of Islamic bank customers in using e-banking and m-banking. Design/methodology/approach Data collection is carried out by the self-administered survey method with Islamic bank customers as target population. Multivariate analysis of variance and multiple linear regression are applied for data analysis. Findings Customer intimacy not only encourages the emergence of customer loyalty directly, but also affects the factors that determine customer loyalty itself, such as perceived usefulness, perceived ease of use, perceived risk, trust, sharia compliance and satisfaction. In other words, customer intimacy has a direct and indirect influence on loyalty. Originality/value This paper offers an extended TAM constructs to study the role of customer intimacy in increasing loyalty by considering various variables, namely, perceived risk, trust, Sharia compliance and satisfaction. Similar research is still very limited in the banking marketing literature, especially in Islamic banks context.
ORGAN CULTURE TECHNIQUES WITH MYCOPLASMAS *

The technique of organ culture permits the maintenance in vitro of complete rudiments or fragments of organs in a viable, organized, differentiated condition. This experimental model has played an important role in the advancement of knowledge in the areas of embryology, endocrinology, and metabolism' since general and specialized activities of normal cells can be examined. The first studies involving respiratory tract organ cultures were done by Carleton2 in 1925, but the effect of viruses on ciliated epithelium in such cultures was not examined until 1957.3 Since these early experiments, organ cultures of respiratory tract have been used for the study of many v i r ~ s e s . ~ Tracheal organ culture was first used for the study of mycoplasmas in 1969.5 To date, mycoplasma species that have been studied in tracheal organ culture include: M . pne~moniae ,~-"'~*'~ M . homini~,5,~,9*11,'3.1~,~3 M . s a l i ~ a r i u r n , ~ ~ ~ * ~ * ' ~ M . f e r r n e n t a n ~ , ~ ~ ~ M . orale type 1 ,5359J4 M . mycoides var. capri,6J1*12*14-23 T s t r a i n ~ , ~ J ~ J ~ M . agala~tiae,'~ M. mycoides var. rnyc~ides,'~*'~ M . syn~v iae , '~ M . g a l l i ~ e p t i c u r n , ~ ' * ~ ~ * ~ ~ M . p~lmonis,1~*25,~7 M . laidlawii,13 M . h y o r h i n i ~ , ~ ~ * ~ ~ , ~ ~ M . g a l l i n a r ~ m , ~ ~ M . g r a n u l a r ~ m , ~ ~ M . h y o s y n o ~ i a e , ~ ~ and M . hyp~pneumoniae . ~~ Tracheal tissue used in these studies involving mycoplasmas was obtained from human fetuses, chicken embryos, infant pigs, adult hamsters, and adult mice. This report presents techniques developed to examine the pathogenesis of M. pneumoniae disease in hamster tracheal organ culture; available data encourage more general use of organ culture methods for investigation of the interrelationships between other microbial agents and appropriate host tissues.