Miracle-dz/UniFAR-FTUs huggingface dataset:
Assessment of salivary and gingival crevicular fluid Periostin levels in chronic periodontitis patients before and after non-surgical periodontal therapy

Introduction: Periostin is a matricellular protein highly expressed by the fibroblasts in the periodontal ligament. It is entangled in the maintenance of periodontal integrity which is affected by periodontal disease.Aim: this study aimed to compare both GCF and salivary periostin levels during periodontal disease to their levels after non- surgical periodontal therapy.Subjects and methods: The present study was performed on a total of 30 subjects, 13 males and 17 females. The thirty selected participants were sampled at baseline and after receiving the non-surgical periodontal treatment.Results: In GCF, there was a statistically significant (at P ≤ 0.05) increase in mean Periostin level after treatment. While in saliva, there was a statistically significant (at P ≤0.05) decrease in mean Periostin level after treatment. Conclusion Our results suggested that GCF periostin level may be considered as a reliable marker in the evaluation of periodontal disease activity, while salivary periostin level could have a promising diagnostic potential. So, further investigations are recommended.
Knowledge and Perception of Hand Hygiene among House Officers in a Tertiary Health Care Centre in Punjab, Pakistan

Abstract Background: Â Â HandÂ hygieneÂ isÂ oneÂ ofÂ theÂ primaryÂ measuresÂ toÂ reduceÂ healthÂ careÂ associatedÂ infectionsÂ (HCAIs). Â ThereÂ isÂ aÂ needÂ toÂ exploreÂ theÂ conceptÂ ofÂ handÂ hygieneÂ amongÂ theÂ medicalÂ graduates. Objective: Â Â ToÂ assessÂ theÂ knowledgeÂ andÂ perceptionÂ ofÂ handÂ hygieneÂ amongÂ houseÂ officersÂ inÂ aÂ tertiaryÂ healthÂ careÂ centre. PatientsÂ andÂ Methods:Â Â ThisÂ crossÂ sectionalÂ surveyÂ wasÂ conductedÂ inÂ theÂ departmentsÂ ofÂ Paediatrics,Â InternalÂ Medicine,Â SurgeryÂ andÂ ObstetricsÂ /Â Gynaecology,Â inÂ affiliatedÂ hospitalsÂ ofÂ KingÂ EdwardÂ MedicalÂ UniversityÂ /Â MayoÂ Hospital,Â LahoreÂ fromÂ OctoberÂ toÂ DecemberÂ 2015. Â WorldÂ HealthÂ Organizationâ€™sÂ validatedÂ handÂ hygieneÂ knowledgeÂ andÂ perceptionÂ questionnaireÂ wasÂ used. Â AÂ totalÂ ofÂ 100Â freshÂ medicalÂ graduates,Â whoÂ passedÂ theirÂ MBBSÂ inÂ MarchÂ â€“Â AprilÂ 2015,Â workingÂ asÂ houseÂ officersÂ wereÂ includedÂ inÂ theÂ studyÂ byÂ non-probabilityÂ convenientÂ sampling. Â TheÂ dataÂ wereÂ enteredÂ inÂ SPSSÂ 20Â forÂ statisticalÂ analysis. Â ChiÂ squareÂ testÂ wasÂ usedÂ forÂ comparison. Results: Â Â OfÂ 100Â houseÂ officersÂ approached,Â 67Â participatedÂ inÂ thisÂ study. Â OnlyÂ 20Â (29%)Â hadÂ receivedÂ formalÂ trainingÂ inÂ handÂ hygieneÂ andÂ 40Â (59%)Â practicedÂ routineÂ useÂ ofÂ alcoholÂ handÂ rub. Â TheÂ studyÂ didÂ notÂ documentÂ satisfactoryÂ levelÂ ofÂ knowledgeÂ regardingÂ handÂ hygiene. Â Overall,Â 27Â (40.3%)Â houseÂ officersÂ hadÂ correctÂ knowledgeÂ ofÂ mainÂ routeÂ ofÂ transmissionÂ ofÂ potentialÂ harmfulÂ germs,Â whileÂ 23Â (34.3%)Â houseÂ officersÂ hadÂ correctÂ knowledgeÂ ofÂ mainÂ sourceÂ ofÂ germsÂ inÂ HCAI. Â Only,Â 41Â (61.2%)Â houseÂ officersÂ correctlyÂ knewÂ ofÂ 20Â secondsÂ asÂ theÂ minimumÂ timeÂ requiredÂ forÂ effectiveÂ alcohol-basedÂ handÂ rub. Â TheÂ houseÂ officersÂ wereÂ ofÂ theÂ opinionÂ thatÂ alcoholÂ â€“Â basedÂ handÂ rubÂ mustÂ beÂ availableÂ atÂ healthÂ â€“Â careÂ facilityÂ atÂ eachÂ pointÂ ofÂ careÂ andÂ awarenessÂ postersÂ shouldÂ beÂ displayedÂ atÂ sameÂ pointsÂ asÂ reminders. Â ActionsÂ takenÂ byÂ leadersÂ andÂ managersÂ regardingÂ effectiveÂ measuresÂ towardsÂ handÂ hygieneÂ wereÂ consideredÂ effectiveÂ inÂ improvingÂ theÂ handÂ hygieneÂ practices. Conclusion: Â Â TheÂ unsatisfactoryÂ levelÂ ofÂ knowledgeÂ regardingÂ handÂ hygieneÂ indicatesÂ thatÂ theÂ houseÂ officersÂ requireÂ increasedÂ emphasisÂ onÂ handÂ hygieneÂ educationÂ andÂ improvementÂ inÂ theirÂ currentÂ primaryÂ trainingÂ asÂ wellÂ asÂ undergraduateÂ curricula. Â
Learning analytics integrating student attendance data

With UK Higher Education (HE) ever more scrutinised with the Teaching Excellence Framework, changes to finance and media attention student welfare and retention is becoming ever more important. Institutions are turning to technological methods to assist wherever possible. Use of Learning Analytics (LA) systems, as a result, is booming. Institutions are deploying these systems to exploit the wealth of information that they hold on their students. LA systems have historically focused on interactions between a student and their course in the form of results or participation within a Virtual Learning Environment. However, their focus tends to be on analysing outcomes based on performance, with other factors occasionally mixed in. If early identification is to the be goal of an analytics system, new sources of data must be added to the models. These new data sources will need to be timely and robust. Almost all institutions, as they have a visa monitoring requirement, monitor student attendance at timetabled and other events. This attendance data is rarely included in LA models. This thesis shows how a simple synthetic metric, the Bangor Engagement Metric (BEM), can be used in conjunction with standard Data Science and ML techniques can produce a powerful predictive model as early as Week 4 of Semester 1 (~end of October each year). It proves, through a series of experiments, that a single algorithm is suited to this unbalanced class classification problem. The model is then proven, against both past and future unseen data, to produce prediction accuracies in excess of 93% at Bangor University reaching as high as 97.33%. These trials go on to show that the only improvement to this level of accuracy is to utilise the attendance data from all of Semester 1. In addition, the results provide a
Liquid‐Phase Quasi‐Epitaxial Growth of Highly Stable, Monolithic UiO‐66‐NH2 MOF thin Films on Solid Substrates

Abstract High quality, monolithic UiO‐66‐NH2 thin films on diverse solid substrates have been prepared via a low temperature liquid phase epitaxy method. The achievement of continuous films with low defect densities and great stability against high temperatures and hot water is proven, clearly outperforming other reported types of MOF thin films.
Attenuation of cGAS/STING activity during mitosis

To limit deleterious interferon responses with each cell division and open mitosis, cGAS/STING activities are shown to be dampened-with Golgi vesiculation preventing activation of STING. The innate immune system recognizes cytosolic DNA associated with microbial infections and cellular stress via the cGAS/STING pathway, leading to activation of phospho-IRF3 and downstream IFN-I and senescence responses. To prevent hyperactivation, cGAS/STING is presumed to be nonresponsive to chromosomal self-DNA during open mitosis, although specific regulatory mechanisms are lacking. Given a role for the Golgi in STING activation, we investigated the state of the cGAS/STING pathway in interphase cells with artificially vesiculated Golgi and in cells arrested in mitosis. We find that whereas cGAS activity is impaired through interaction with mitotic chromosomes, Golgi integrity has little effect on the enzyme’s production of cGAMP. In contrast, STING activation in response to either foreign DNA (cGAS-dependent) or exogenous cGAMP is impaired by a vesiculated Golgi. Overall, our data suggest a secondary means for cells to limit potentially harmful cGAS/STING responses during open mitosis via natural Golgi vesiculation.
Peran Pendidikan Jasmani Melalui Kegiatan Ekstrakurikuller Futsal Dalam Mencegah Kenakalan Remaja Pada Siswa SMK N 1 Karimun

Penelitian ini bertujuan untuk mengetahui dampak dari upaya yang dilakukan untuk mencegah kenakalan remaja pada siswa Sekolah Menengah Atas. Penelitian ini merupakan penelitian kualitatif dengan metode studi kasus. Teknik pengumpulan data dilakukan dengan cara observasi, kajian literatur, penyebaran kuisioner dan wawancara. Teknik analisa data mengunakan teknik deskriptif dengan cara reduksi data, penyajian data dan pengambilan kesimpulan. Hasil penelitian menyimpulkan bahwa pendidikan jasmani dapat mencegah kenakalan remaja dengan tiga indikator yaitu pengembangan kegiatan olahraga unggulan, gaya kepemimpinan guru penjas dan partisipasi keseluruhan warga sekolah. Kata Kunci: Kenakalan, Remaja dan Pendidikan Jasmani
Are Women Adequately Informed by Publications on Contraception? AnInternational Perspective

The paper argues by way of an international comparison that U.S. research publications as well as public health media provide inadequate information on contraceptive methods. To support this argument, the paper analyses the most salient publications as well as websites of public health agencies and compares them to European publications. It concludes that U.S. research has to intensify efforts to strive for accuracy and completeness to enable women to exert their autonomy as fully informed patients.
Response of osteoarthritis biomarkers after a rehabilitation program: study protocol

Background: Knee osteoarthritis is a progressive degenerative joint disease and remains a leading cause of pain, physical impairment and decline in health-related quality of life in adults. Despite its incidence being amongst the highest in chronic diseases, effective biomarkers are not available to assist in its management. The main goal of this study is to identify mediators that serve as biomarkers and investigate if the levels of these biomarkers will be correlated to the efficacy of a rehabilitation program. Methods: This is a prospective cohort study with 65 participants. Patients with mild-to-moderate symptomatic knee osteoarthritis will be recruited. The Rehabilitation Program will consist of three session/week during eight weeks. Assessment about functional evaluation will be performed before and after treatment, using the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) and EuroQOL-5D (Euro quality of life - five dimension) scales, Visual Analog Scale (VAS), and physical function tests (time up and go, isometric strength testing and kinematic gait analysis). Serum levels of classical pro-inflammatory cytokines, hyaluronan and high mobility group box 1 protein (HMGB-1) will be evaluated. The primary outcome is the change in WOMAC scale from baseline to end. Statistical analyses will be used to determine correlation of physical improvement and serum biomarkers. Adverse events will be monitored throughout the study. Conclusions: This trial expect to study the correlation between the anti-inflammatory effects of rehabilitation program derived factors that may be involved in suppressing cytokine induction via suppressing HMGB-1. Trial registration: Clinicaltrials.gov - NCT02964624.
Extreme value approach to CoVaR estimation

The global financial crisis of 2007-2009 highlighted the crucial role systemic risk plays in ensuring stability of financial markets. Accurate assessment of systemic risk would enable regulators to introduce suitable policies to mitigate the risk as well as allow individual institutions to monitor their vulnerability to market movements. One popular measure of systemic risk is the conditional value-at-risk (CoVaR), proposed in Adrian and Brunnermeier (2011). We develop a methodology to estimate CoVaR semi-parametrically within the framework of multivariate extreme value theory. According to its definition, CoVaR can be viewed as a high quantile of the conditional distribution of one institution’s (or the financial system) potential loss, where the conditioning event corresponds to having large losses in the financial system (or the given financial institution). We relate this conditional distribution to the tail dependence function between the system and the institution, then use parametric modelling of the tail dependence function to address data sparsity in the joint tail regions. We prove consistency of the proposed estimator, and illustrate its performance via simulation studies and a real data example.
Hodgkin Lymphoma in Jordan; A Retrospective Analysis of 477 Cases in King Hussein Cancer Centre

Abstract 4862 BACKGROUND Jordan is a small country with an estimated mid year population in 2008 of 5 850 000, 3015000 of whom are males and 2 835 000 are females (male: female ratio 1.06: 1). (Department of Statistics Jordan, 2008). About 12.7 % of the population is under 5 years old, and 37.3 % under 15 years old. 11%if the population are 15–19 year old, with a M:F ratio 1.06:1 as well) Only 3.3 % of the total population is above the age of 65 years old (sex ratio of 1.01 male per 1 female in this age group). According to the Jordan Cancer Registry Report for 2008, Lymphoma is the fourth most common Cancer in the country. A total of (4606 ) new cases of cancer were recorded among Jordanians in the year 2008, 333 (7.2%) of whom had a diagnosis of lymphoma.111 (2.4%) were diagnosed as Hodgkin9s lymphoma (HL), and 222 (4.8%) as Non Hodgkin Lymphoma(NHL). OBJECTIVE In this study, we aim to characterize some of the clinico-pathological features of Hodgkin lymphoma in Jordan by analyzing the data available for patients referred to King Hussein Cancer Center over a seven year period. PATIENTS AND METHODS A retrospective analysis was conducted of adults (>18 years) lymphoma patients referred to KHCC, between 1/1/2003 and 31/12/2010. Clinical features and histological subtypes were prospectively established for all patients registered in the Lymphoma Service Database. Pathology review and original paraffin block were mandated for all patients. RESULTS Over the 8 year period of 2003–2010,1329 lymphoma patients were referred to KHCC and registered in the Lymphoma Service Database, of whom 477 (35.9%) were diagnosed with Hodgkin9s lymphoma. Among this group all 477 patients were adults 18 years or older (100%), as children are treated in a different department. The median age was 35 years, (with an age range of 18–77), and 5% of patients were above the age of 60. 290 (61 %) of the patients were males, 187 (39%) were females, with a male to female (M:F) ratio of 1.55:1. 276 (57.8%) of the HL cases had a diagnosis of nodular sclerosis Hodgkin lymphoma (HDNS), making it the most common histological subtype. 120(25.2%) had mixed cellularity Hodgkin lymphoma (HDMC), 9 (1.9%) had lymphocyte-rich Hodgkin lymphoma (HDLR), and 6 (1.2%) had lymphocyte-depleted Hodgkin (HDLD). Nodular lymphocyte predominance Hodgkin lymphoma (NLPHD) cases were 33, and constituted 6.9% of the HL cohort. CONCLUSION Hodgkin lymphoma appears to constitute a bigger share of the lymphoma burden in Jordan, as opposed to Europe and the US. Clinico-pathological features, however, appear to be closer to those described in Western countries, with similar incidence of HDNS, and HDMC subtypes, but possibly with less incidence of HDLR and HDLD subtypes. Disclosures: No relevant conflicts of interest to declare.
New times for HRM? Well-being oriented management (WOM), harmonious work passion and innovative work behavior

The purpose of this paper is to measure and conceptualize the concept of well-being-oriented management (WOM), and to investigate the relationship between well-being oriented management (WOM), harmonious work passion, and innovative work behavior (IWB). ,In a sample of 362 senior managers, the authors used a two-wave structural equation model to verify whether the relationship between WOM and IWB was mediated by harmonious work passion. ,This study reveals that human resource practices (HRM) oriented toward well-being, namely WOM, can be measured and conceptualized. In addition, WOM implemented over a period of one year, subsequently fostered IWB. Further, the role of harmonious passion as a catalyst in the relationship between these HRM practices and IWB was also examined. ,Drawing upon the social exchange theory and the Job Demands-Resources model, our contributions are threefold: to conceptualize and empirically measure WOM; to discover the effect of WOM on IWB, and to assess the mediating role of harmonious work passion in the relationship between WOM and IWB.
Effect of size grading on the growth of pirarucu Arapaima gigas reared in earthen ponds

Size grading is a common management practice in fish farming to minimize growth variability. Such practice has not been established for pirarucu Arapaima gigas . Therefore, the present study assessed the effect of size grading on the growth of pirarucu. Juvenile pirarucu were divided into three groups: ungraded fish (U: mean initial weight 1.12 kg), small fish (S: mean initial weight 0.81 kg), and large fish (L: mean initial weight 1.36 kg), and reared for 129 days (phase I) and 158 additional days (phase II), consecutively. No significant difference was observed in the final length, specific growth rate, biomass, survival and feed conversion rate between fish groups. Ungraded fish presented a greater decrease in the coefficient of variation for weight in phase I than in phase II. Size sorting resulted in significantly higher growth after 287 days of farming in the L-graded fish (9.49 kg, final weight), followed by the ungraded group (8.80 kg) and S-graded group (8.01 kg). However, the mean weight of pooled S- and L-graded fish was similar to the ungraded fish group in phase I and phase II, indicating that grading did not improve the general performance of pirarucu in captivity.
Thrombocytopenia as a Clue of Vivax Malaria in Endemic Region, Sudan

Reduction in circulating platelets is observed relatively frequently in cases of malaria due to P. vivax. 61 patients with confirmed vivax malaria were enrolled in this study and the platelets were counted by hematological analyzer. our study revealed that 77.1% had platelets count less than 150,000/ μl , thrombocytopenia grade 1 represent 43%, grade 2 represent 19.8%, grade 3 represent 9.8% and grade 4 represent 4.9%. Thrombocytopenia should be a consideration as a clue to the presence of malaria in endemic region.
Assessing the Risk of Manual Handling of Patients and Its Relationship with the Prevalence of Musculoskeletal Disorders Among Nursing Staff: Performance Evaluation of the MAPO and PTAI Methods

Background: Manual handling of patients without using proper devices built for this purpose is the most important risk factor causing musculoskeletal disorders (MSDs) among nursing staff. Objectives: The aim of the present study was to determine the prevalence of MSDs, assess the risk of manual handling of patients, and identify the risk factors related to the development of such disorders among nursing staff. Methods: This cross-sectional study was conducted in 2015 and included 220 nurses from 24 wards who were working in Baqiyatallah hospital, Tehran, Iran; their duties mainly involved patient handling. The participants were selected based on the random stratified sampling method. In this study, the Nordic musculoskeletal questionnaire, demographic questionnaire, movimentazione and assistenza di pazienti ospedalizzati (MAPO), and patient transfer assessment instrument (PTAI) methods were applied as data collection tools. In addition, Spearman correlation coefficients and binary and multiple logistic regressions were used to determine the possible relationships between the variables. Results: The prevalence of MSDs among the participants over the past 12 months was found to be 79.5%. The results for the risk factors showed that the lower back, neck, shoulders, and upper back were the most affected areas of the body. According to the MAPO and PTAI, 60% and 40% of the wards, respectively, are at risk of MSDs. A significant relationship between MAPO and PTAI was found, with a coefficient correlation of 0.252. Based on the statistical analysis, positively significant relationships were found between body mass index, gender, nurse-to-bed ratio, final PTAI and MAPO indices, and MSDs. Conclusions: The prevalence of MSDs among the nurses was high, and the occurrence of such disorders was found to be related to the scores of MAPO and PTAI indices. Based on the results, these two indices can be used as appropriate tools to assess the risk of MSDs in patient handling by nursing staff. The risk of developing MSDs can be lowered through interventional programs, such as providing and equipping hospitals with the tools required for patient handling and educating staff on how to properly use such devices. In addition, increasing the nurse-to-bed ratio will lower the burden for the nurses in patient handling.
Increasing Conceptual Understanding through CCM-CCA Based Learning Device

Learning must be focus on creating conceptual change in students. One of the alternatives is using CCM-CCA-based learning devices because CCM-CCA is a learning model that can create cognitive conflict as a condition for conceptual change. This research is directed to develop learning devices based on CCM-CCA that can improve conceptual understanding. The learning devices developed to consist of LEU (Learning Events Units) and SW (Students’ Worksheet) for Newton's Law material about motion and work-energy. The results of the validation of learning devices (LEU and SW validation) indicate that these devices are valid in content and construction so that they are suitable for the learning process. Based on the results of the implementation of the device and the test results, it was concluded that the CCM-CCA-based learning device was able to improve conceptual understanding. The increase was obtained through an N-Gain analysis with an N-Gain value for LEU of 60.44% and SW of 54.01%. The percentage of the N-Gain score is included in the increase with the medium category.
Corporate Social Responsibility And Company Performance

The purpose of this research is to analyze the influence of corporate social responsibility and capital structure on financial performance of high-profile company. Population in this study is all high-profile companies listed in Indonesia Stock Exchange (IDX) in the period of 2010-2015. The sample was selected by purposive sampling, hence 225 samples were obtained. This research uses secondary data from Indonesian Capital Market Directory (ICMD) and IDX companies. Structural equation modeling (SEM) is used as statistical tool. The hypothesis measurement model showed better fit as indicated by the goodness of fit indices, and also could fullfill convergent validity which reflected by the significant factor loadings. The structural model of financial perfromance also could reach better fit and it found that corporate social responsibility has a positive and significant effect on financial performance; and the capital structure has a negative and significant influnce on financial performance in high-profile companies listed on the IDX.