Miracle-dz/UniFAR-FTUs huggingface dataset:
Developing Indonesian version of childbirth self-efficacy inventory (Cbsei)-C32

Introduction: Women readiness and self-efficacy for pregnancy and childbirth is an important issue which usually assessed by using CBSEI-32 but currently no evaluation is ever conducted nor Indonesian version of this instrument ever developed to enhance subject understanding. Therefore, this study aimed to develop the Indonesian Language version of CBSEI (childbirth self-efficacy inventory) instrument. Method: A quantitative study was conducted by involving 73 pregnant mothers in their trimester III either as the primigravida or as multigravida. The selected respondents are those who lived in the working area or visited several health care centres in the area between July-August 2018. The content validity was tested by using Aiken V analysis and the construct validity was assessed using Kaiser-Meyer-Olkin (KMO) and Bartlett’s test. Finally, the reliability test was conducted using Alpha Cronbach. Result: Analysis revealed that the Aiken V value of the instrument was in the range of 0.67-1 for the outcome expectancy and 0.75-1 for efficacy expectancy. 16 items in outcome expectancy showed KMO value > 0.5 with MSA value between 0.648-0.957. Meanwhile, 16 questions in efficacy expectancy also had KMO value > 0.5 with a MSA range between 0.798-0.937 respectively. The average values of the instrument validity for the outcome expectancy and efficacy expectancy were 0.740 and 0.726 respectively. Finally, Alpha Cronbach value for both outcome expectancy and efficacy expectancy was 0.94. Conclusion: According to the analysis, it can be concluded that CBSEI-C32 in Indonesia language version was valid and reliable instrument to be applied in pregnant mother in Indonesia.
Effects of Health promotion program using laughing on interpersonal relationship and self-esteem of mental patients

This study was conducted on a health promotion program, which consisted of "Laughing, Health Education and rhythm for the total of 24 weeks from Aug to Dec of 2014 subject on 16 mental patients who were registered and cared by a mental heath promotion center. This study was looked into how the health promotion program is to affect on the interpersonal relationship, self-esteem of the mental patients. After the program was done; the results of the mental patients' interpersonal relationship and building self-esteem were improved. It could prevent its patients' lifestyle disease as well.
Lead to Tumor Elimination and Host B7H6-Specific Bispecific T Cell Engagers

Substantial evidence showed that T cells are the key effectors in immune-mediated tumor eradication; however, most T cells do not exhibit antitumor speciﬁcity. In this study, a bispeciﬁc T cell engager (BiTE) approach was used to direct T cells to recognize B7H6 + tumor cells. B7H6 is a speciﬁc ligand for the NK cell–activating receptor NKp30. B7H6 is expressed on various types of primary human tumors, including leukemia, lymphoma, and gastrointestinal stromal tumors, but it is not constitutively expressed on normal tissues. Data from this study showed that B7H6-speciﬁc BiTEs direct T cells to mediate cellular cytotoxicity and IFN- g secretion upon coculturing with B7H6 + tumors. Furthermore, B7H6-speciﬁc BiTE exhibited no self-reactivity to proinﬂammatory monocytes. In vivo, B7H6-speciﬁc BiTE greatly enhanced the survival beneﬁt of RMA/B7H6 lymphoma-bearing mice through perforin and IFN- g effector mechanisms. In addition, long-term survivor mice were protected against an RMA lymphoma tumor rechallenge. The B7H6-speciﬁc BiTE therapy also decreased tumor burden in murine melanoma and ovarian cancer models. In conclusion, B7H6-speciﬁc BiTE activates host T cells and has the potential to treat various B7H6 + hematological and solid tumors. The Journal of Immunology , 2015, 194: 000–000.
Drops in physical performance during intermittent small-sided and conditioned games in professional soccer players

Purpose. The purpose of this study was to identify variations in external load measures between sets (3 × 4’/2’ rest) of small-sided and conditioned game formats (goalkeeper + 5 vs. 5 + goalkeeper with specific tactical demands). Methods. Overall, 10 male professional soccer players (age: 28.1 ± 3.8 years, experience: 7.9 ± 2.9 years, height: 180.3 ± 5.8 cm, weight: 76.5 ± 6.3 kg) from a team competing in the first Portuguese league and in the UEFA Europa league participated in the study. Distance covered, high intensity running (HIr), maximal velocity (MV), high speed running (HSr), very high intensity running (VHIr), and player load (PL) were monitored by using global positioning system units. Results. Very large decreases in HIr (–62.6, effect size [ ES ]: –2.04) were found from set 1 to set 3. Large decreases in distance covered (–12.8%, ES : –1.28) and MV (–19.4, ES : –1.95) were observed from the first to the third set. Large decreases in HSr (–80.2%, ES : –1.78), moderate decreases in PL (–7.6%, ES : –0.64), and large decreases in VHIr (–83.0%, ES : –1.88) were reported between the first and the third set. Conclusions. The results of the present study indicate a significant drop in external load performance when comparing the first and the second sets with the third set.
An Analysis of the Notion of Need for the Representation of Public Services

Many Public Administrations structure their services around the notion of users’ need. However, there is a gap between private, subjectively perceived needs (self-attributed) and needs that are attributed by PA to citizens (heteroattributed). Because of the gap, citizens’ needs are often only partially satisfied by PAs services. This gap is in part due to the fact that the meaning of the word “need” is ambiguous and full of antinomic nuances. The purpose of this paper is to formulate a definition of “need” suitable for citizens’ needs management with respect to PA’s services offering, and to provide an accurate ontological analysis of the notion of “need” and the network of concepts that relate to it.
Extent of Student-College Matching for Students Enrolled in Special Education Services

This study investigates the prevalence of postsecondary student-college match for students enrolled in special education services at the secondary education level by using data from the Education Longitudinal Study of 2002. This study examines alternative student-college match scenarios – including undermatch, match, and overmatch – and addresses the gap in research specific to college match and students in special education. Findings indicate that students who enrolled in special education services in high school undermatched to schools they had the potential of enrolling in. Moreover, undermatching for this student group increased if students were Black, Hispanic, or of low socioeconomic status.
Estrogen and Progesterone Receptor Assessment: Current Diagnostic and Management Issues

Abstract Steroid receptors were among the very first prognostic and predictive markers discovered in cancer; in fact, they paved the road to targeted patient management in breast cancer. Due to their paramount role in prognostication and treatment decision-making, they are the most important ancillary study to be performed on any newly diagnosed or recurrent breast cancer. This necessitates reliable, reproducible and validated assessment of ER and PR. Diagnostic pathology laboratories performing this assessment have to demonstrate strict adherence to ASCO/CAP guidelines on tissue fixation, preparation, test validation as well as on interpretation of ER/PR status. This review discusses various methodologies being used for hormone receptor status assessment, including the guidelines regarding their validation and interpretation.
Lycopene attenuates LPS-induced liver injury by inactivation of NF-κB/COX-2 signaling.

AIM This study aimed to investigate the effect of lycopene on LPS-induced liver injury in mice and its mechanisms. METHODS Male C57bl/6 mice were randomly assigned to three groups: sham control group (S-C), LPS control group (L-C), lycopene treatment group (L-T). The mice from the L-T were treated with lycopene for 2 weeks, and the remaining mice with solvent. Afterwards, the mice from the L-C and the L-T received an intraperitoneal injection of LPS (20 mg/kg, dissolved in sterile saline), and the S-C mice were injected with sterile saline. Serum levels of alanine transaminase (ALT) and aspartate aminotransferase (AST) were determined for analysis of liver function. Levels of inflammatory cytokines including tumor necrosis factor (TNF)-α and interleukin (IL)-6, malondialdehyde (MDA) content, and the activity of superoxide dismutase (SOD), were detected in serum. Liver tissues were operated for morphologic analysis and determination of protein by western blot. RESULTS Pretreatment with lycopene significantly decreased levels of ALT, AST, and TNF-α and IL-6, reduced MDA content, and increased activity of SOD in serum compared with the L-C mice. Lycopene increased expression of nuclear factor-erythroid 2 related factor 2 (Nrf2), and reduced expression of cyclooxygenase (COX)-2, and phosphorylation of nuclear factor-kappa B (NF-κB) and extracellular regulated protein kinases 1/2 (ERK1/2). CONCLUSION The results showed that lycopene attenuates LPS-induced liver injury by reducing NF-κB/COX-2 signaling by upregulation of Nrf2/HO-1 activation.
Economies of Scale and Heterogeneity in Provision of Public Goods: Evidence from School Consolidation in China

This paper examine the trade-offs faced by central decision-makers responsible for delivering local public goods. From 2000 to 2010, China closed more than 50% of its primary schools. While smaller and academically weaker schools were closed and students’ test scores increased, students paid additional cost due to a longer home-to-school commute post school closure. This paper builds and estimates a structural model of local governments’ decision-making to rationalize these stylized facts and to recover the preferences of local authorities. I pay particular attention to cases when there may be heterogeneous productivity across schools, increasing returns in schooling production, and home-to-school commuting costs. The estimation shows that schools that were closed had lower mean productivity. Some very small schools with relatively high productivity were also closed. The upper bound of distance cost estimated with moment-inequalities indicates that distance cost was under-weighted in local governments’ decision.
Heterogeneity in the Efficiency of Intrahousehold Resource Allocation: Empirical Evidence and Implications for Investment in Children

We present some of the first evidence of within-sample variation in the efficiency of intrahousehold resource allocation. In a sample of rural, low-income Mexican households, observed consumption patterns are Pareto efficient for households with relatively old heads, but not households with relative young heads. This variation in efficiency has important welfare implications: younger households invest less in children’s education and, in particular, their education investments are less sensitive to the receipt of cash transfers. The link between inefficient household resource allocation and underprovision of public goods follows naturally from standard models but we believe this has never before been documented empirically. Heterogeneity in efficiency by household head age may be due to cohort and/or lifecycle effects. The specific patterns of heterogeneity we find are more consistent with cohort than lifecycle effects, which means that average efficiency may decline over time in this population. From a policy perspective, these results highlight a limitation of cash transfers relative to other forms of poverty alleviation policy in settings where at least some households engage in inefficient consumption behaviour. Many papers have already established that the distributional effects of development policy depend on whether households behave as unitary actors; our results emphasize that it is also important to assess whether (some) households behave as efficient collective units.
Nutritional and Heavy Metal Analysis on Four Local Fruits in Awka South Eastern Nigeria

The aim of this study was to assess and evaluate the nutritional and metal analysis on four local fruits. Proximate analysis was carried out to determine the levels of crude protein, crude fiber, total ash, mineral content, lipids and carbohydrates on the four local fruits (Chrysophyllum albidum, Solanum macrocarpon, Aabelmoschus esculentus and Dalium indium. The presence of Lycopene was also determined. Results of the proximate analyses of the fruits indicated that crude protein content ranged from (3.40±0.12% 5.07±0.14)g/100g with Solanum macrocarpon having the highest, ash content was in the ranges of (0.50±0.005.00±0.00)g/100g, crude fiber gave values in the range (3.31±0.31-54.17±0.16)g/100g, moisture content was in the range of (15.00±0.0468.35±1.73)g/100g, it recorded the highest value in Solanum macrocarpon and the least in Abelmoschus esculentus and total carbohydrates was (11.15±0.1432.73±2.30)g/100g with Chrysophyllum albidum having the highest and Dalium indium, the least. Result on lycopene concentration gave Dalium indium with 0.0962mg/g as the highest, others showed appreciable values of 0.0202mg/g, 0.0285mg/g and 0.0147mg/g for S. macrocarpon, C. albidum and A. esculentus respectively. The mineral composition contained in the fruits were calcium which had the highest values in the four fruits (49.622, 65.153, 27.016 and 30.425) ppm, magnesium gave (20.811, 21.291, 11.105 and 11.304) ppm, copper gave (0.075, 0.113, 0.116 and 0.158) ppm, zinc (6.594, 6.452, 3.743 and 5.239) ppm, manganese (1.476, 4.840, 4.050,0.696) ppm, iron (3.486, 5.456, 4.858 and 4.539) ppm, cobalt (0.148, 0.126, 0.064 and 0.123) ppm, lead (1.410, 0.170, 0.070, 0.030) ppm, nickel (0.077, 0.042, 0.065 and 0.040)ppm, cadmium (0.00, 0.096, 0.039, 0.018)ppm, chromium (0.250, 0.142, 0.00, 0.073) ppm and the least values in aluminium (0.000.130) ppm for C. albidum, A. esculentus, D. indium and S. macrocarpon respectively. The collection of nutritional information may serve as a basis for increased consumption and utilization.
ASIAN YOUTH JOURNAL OF BIOLOGY

The chimeric gene fusions EML4-ALK and KIF5B-ALK have been previously identified as potent oncogenic drivers in non-small-cell lung carcinoma (NSCLC), with malignant transformation arising from the constitutive tyrosine kinase activity of their ALK domains. Despite the initial success of ALK-positive lung cancer therapies involving ALK and Hsp90 inhibitors, the susceptibility of these approaches to acquired drug resistance and cytotoxicity call for alternative strategies to attenuate ALK-driven oncogenesis. This study investigates the potential of targeting the chaperone-mediated folding mechanisms of these ALK fusions via the key heat shock response transcription factor HSF1, in light of reports that these oncoproteins were intrinsically unstable and prone to misfolding. It was found that expression levels of the isoform EML4-ALK variant 1, as well the novel fusion KIF5B-ALK, are particularly susceptible to Hsp90 inhibition, proteasome degradation and protease digestion, indicating high structural instability and dependence on chaperone activity. Overexpression of KIF5B-ALK was shown to induce HSF1 trimerization and activation, while both EML4-ALK and KIF5B-ALK were shown to increase HSF1 transcriptional activity independent of their kinase function. However, overexpression of HSF1 did not lead to any increase in ALK protein levels. This suggests that inhibiting HSF1 activity may have to be combined with other ALK-directed strategies in order to have any significant therapeutic effect in NSCLCs.
Using critical discourse analysis and the concept of food security to understand pregnant women’s nutrition in Aotearoa/New Zealand

INTRODUCTION While Aotearoa/New Zealand (Aotearoa) is widely recognised as a wealthy developed nation, with a growing economy and a high level of food exports, food insecurity is a rising concern (Graham, Stolte, Hodgetts, & Chamberlain, 2016; Pollard & Booth, 2019; Schlichting, Hashemi & Grant, 2019). Most recent available data highlight that 7.3% of Aotearoa households experience food insecurity (Graham & Jackson, 2017). Food security data in Aotearoa are similar to international data, with more women food insecure compared to men (Broussard, 2019; de Schutter, 2016). The National Council of Women of New Zealand (2019) has identified poverty as the major economic issue facing many women in Aotearoa, with women consistently earning less than men. Hence women living in poverty who are pregnant face greater concerns and can become more vulnerable economically, socially and physically. ABSTRACT
Informal Learning about Teaching among Novice University Professors

In this article, we present results of a study on informal learning about teaching among novice university professors at one university in Spain. The study identified teaching competencies developed through informal learning, strategies of informal learning used, and organizational factors that might foster or hinder the acquisition of teaching competencies. We gathered data through 18 individual interviews with novice university faculty, two focus groups with university professors, a document analysis and a focus group of experts. We conducted content analysis of the transcripts of the interviews and focus groups, as well as the documents obtained. The results showed that the competencies most often acquired from informal learning are interpersonal skills, methodologies, planning and content mastery. They are primarily acquired through strategies such as peer interaction and experimentation in practice. The main support for informal learning is the organizational climate, while the main barriers are organizational culture and training policy. The research contributes to understand the phenomenon of informal learning about teaching by novice professors, which is a topic not covered widely at the level of Higher Education.
A Musical Instrument based on 3D Data and Volume Sonification Techniques

Musical expressions are often associated with physical gestures and movements, which represents the traditional approach of playing musical instruments. Varying the strength of a keystroke on the piano results in a corresponding change in loudness. Computer-based music instruments often miss this important aspect, which often results in a certain distance between the player, his instrument and the performance. In our approach for a computer-based musical instrument, we use a system that provides methods for an interactive auditory exploration of 3D volumetric data sets, and discuss how such an instrument can take advantage of this music-based data exploration. This includes the development of two interaction metaphors for musical events and structures, which allows the mapping of human gestures onto live performances of music.
University of Birmingham Complications of spinal cord stimulation and peripheral nerve stimulation techniques

Objective: Spinal cord and peripheral neurostimulation techniques have been practiced since 1967 for the relief of pain and some techniques are also used for improvement in organ function. Neuromodulation has recognised complications, although very rarely do these cause long term morbidity. The aim of this article is to present a review of complications observed in patients treated with neurostimulation techniques. Methods: A review of the major recent publications in the literature on the subjects of spinal cord, occipital, sacral and peripheral nerve field stimulation was conducted. Results: The incidence of complications reported varies from 30% to 40% of patients affected by one or more complications. Adverse events can be subdivided into hardware related complications and biological complications. The commonest hardware related complication is lead migration. Other lead related complications such as failure or fracture have also been reported. Common biological complications include infection and pain over the implant. Serious biological complications such as dural puncture headache and neurological damage are rarely observed. Conclusions: Spinal cord and peripheral neurostimulation techniques are safe and reversible therapies. Hardware related complications are more commonly observed than biological complications. Serious adverse events such as neurological damage are rare.
Final Report: Expressive Power of Parametrized Quantum Circuits

Parametrized Quantum Circuits provide a near-term plausible opportunity to utilize the power of quantum computing. [1] provides an overview of parametrized quantum circuits applied to machine learning. However, as stated in the paper, the main purpose of the survey is pedagogical and nontechnical. For our course project, we aim at a more thorough review with more technical details with a focus on expressive power of parametrized quantum circuits.
Effect of stiffness on tapping performance. Do you rely on force to keep synchronised along with a metronome ?

Several works have examined the robustness of the sound-action loop to auditory delay, and the effects of delay on performance. In this paper we propose a complementary approach, by modifying the stiffness of the tapped object. Participants had to perform synchronous tapping along with a metronome reference, using a one degree-of-freedom haptic device. Two experimental conditions were tested: with and without sound from the tapped object. Dynamics of the experiment were recorded in order to have a closer look at the dynamic factors affecting performance. Results show that the increase of the stiffness of the tapped object leaded to a decrease of the asynchrony, indicating that the modification of the force dynamics has an effect on performance. On the basis of this observation, an explanation of the negative asynchrony effect is proposed. At last, we show that sound feedback improves performance only when the stiffness is very low.
Socioeconomic Inequality in Self-immolation, between Genders; Oaxaca-Blinder Decomposition, Results of Registration-Based Suicide Data

Objective: To assess the important socio-demographic inequalities in self-immolation in between genders. Methods: A cross-sectional study, 2011 to 2016, was conducted. A total of 540 completed suicides were recruited to the study. Data were collected by systematic registration suicide data (SRSD) and Legal Medicine Organization (LMO). The concentration index (CI) was used to determine the inequality. The inequality line was decomposed to find out the main sources of inequality in self-immolation between genders by Oaxaca-Blinder approach. Results: The mean ratio of self-immolation was 21.8% among completed suicides. The decreasing trend was found in self-immolations during 2011-2016 (z = -2.07, p = 0.039), the mean rate in six years, was 2.98 per 100.000 populations. Unemployment −. 043 (−.07, −0.01), married subject’s −. 016 (−.03, −0.00) and low educational level −. 005 (−.01, −0.00) were the main inequality source in females compared to males. Conclusion: Our results suggest that despite the incidence decreasing in self-immolation within 6 years of study period, the inequality was detected in self-immolation. The main socio-demographics in inequalities were lower educational level, married persons and unemployment that prevention programs should be more concentrated in females to a decrease of inequality in self-immolation.