Miracle-dz/UniFAR-FTUs huggingface dataset:
Association between 24-Hour Movement Behaviors and Smartphone Addiction among Adolescents in Foshan City, Southern China: Compositional Data Analysis

Smartphone addiction has become a public health issue. To help reduce smartphone addiction, we assessed the combined effect of 24-Hour Movement Behaviors on smartphone addiction during Corona Virus Disease 2019 (COVID-19) home confinement in Foshan, China. Data were collected in a sample of 1323 senior middle school students ((mean age ± standard deviation): 16.4 ± 0.9 years; 43.46% males) during the COVID-19 lockdown. Their 24-Hour movement behaviors were assessed by a self-reported questionnaire, The Smartphone Addiction Scale-Short Version (SAS-SV). The compositional multiple linear regression model and compositional isotemporal substitution model were used to examine the association between the time budget composition of the day and smartphone addiction. Smartphone addiction occurred in 671 (50.72%) of the 1323 students. Compared with smartphone-addicted adolescents, non-smartphone-addicted adolescents had more moderate-to-vigorous physical activity (MVPA) and sleep duration (SLP), and less sedentary behavior (SB). The distribution of time spent in 24-Hour movement behaviors was significantly associated with smartphone addiction. The negative effect was found for the proportion of time spent in MVPA or SLP (ilr1-MVPA = −0.453, p < 0.001. ilr1-SLP = −3.641, p < 0.001, respectively) relative to the other three behaviors. Conversely, SB was positively associated with the score of smartphone addiction (ilr1-SB = 2.641, p < 0.001). Reallocating one behavior to remaining behaviors was associated with smartphone addiction. Noticeably, the effects of one behavior replacing another behavior and of one behavior being displaced by another behavior were asymmetric. The 24-Hour movement behaviors of adolescents are closely related to smartphone addiction, and future intervention studies should focus on the compositional attribute of 24-Hour movement behaviors.
Pycnogenol improves kinematic parameters of donkeys (Equus asinus) subjected to packing during the dry season

The administration of pycnogenol (PYC) prior to physical exertion had earlier shown to improve gait variables after work. The aim of this study was to determine the effect of PYC on kinematic parameters of donkeys subjected to packing during the dry season. Ten male donkeys served as experimental subjects. Five donkeys were administered with PYC (10 mg/kg) in feed (test group) while another five donkeys were given feed only (control group) for one week pre-packing. Thermal environmental parameters of ambient temperature (AT), relative humidity (RH) and temperature humidity index (THI) were recorded. Kinematic parameters of speed (SP), stride length (SL), stride frequency (SF) and stride duration (SD) using videographic recordings 5 minutes post-packing with each animal walking at a self-selected speed were recorded. The THI values obtained pre- (95.4 ± 3.9) and during (85.3 ± 1.6) packing in the cold-dry season were significantly lower than the values of 148.8 ± 1.8 and 134.8 ± 1.1, respectively obtained during the hot-dry season. The speed recorded in test group (2.0 ± 0.3 m/s) was significantly (P < 0.05) higher when compared to the value (1.3 ± 0.2 m/s) obtained in control group during the hot-dry season while, during the cold-dry season, the test group recorded a significantly (P < 0.05) higher speed (1.3 ± 0.3 m/s) when compared with 1.0 ± 0.2 m/s recorded in control group.The increased speed recorded in the test group indicated that the group performed better as they were less fatigued when compared with the control group. Thus, PYC could be used as a potential agent in the management of fatigue in donkeys used for packing purposes in the region.
Insight into the structural requirements of antimicrobial peptides by multiple validated 3D-QSAR approaches

ABSTRACT Antibacterial peptides (AMPs) are a kind of peptide material produced by the organism to resist the invasion of exogenous pathogens. Several antimicrobial peptides in different structures have been reported. To elucidate the relationship between structure and activity. A molecular modelling study on the nonapeptides using three-dimensional quantitative structure–activity relationship (3D-QSAR) was carried out. Comparative molecular field analysis (CoMFA) and comparative molecular similarity indices analysis (CoMSIA) methods were employed for the identification of significant features of antimicrobial peptides. CoMFA and CoMSIA models all gave best parametric results ( = 0.563, = 0.654 for CoMFA; = 0.656, = 0.8045 for CoMSIA), which suggested that the derived models are highly robust and predictive. In addition, the derived contour maps would provide structural features to improve binding activity, and indicated that steric, electrostatic, and hydrophobic fields play vital roles in improving the activity. The derived models and information may help to provide an insight into the structural requirements for more potent peptides and facilitate the design and optimisation of novel antimicrobial peptides with promising enhanced activity. Furthermore, some potential candidate antimicrobial peptides have been proposed.
Pomolic acid inhibits proliferation of human lung carcinoma cells via induction of apoptosis and suppression of cell migration and invasion

Purpose: To investigate the anti-proliferative effect of pomolic acid on lung cancer cells (A549), and theunderlying mechanism.Methods: The viability of pomolic acid-treated A549 cells was determined by MTT and colony formation assays. Cell colony formation was monitored with acridine orange/ethidium bromide (AO/EB) staining. Protein expressions of Bax and Bcl-2 were assayed by western blotting.Results: Pomolic acid suppressed the growth of A549 cells, with an half-maximal inhibitory concentration of (IC50) of 10 μM (p < 0.05). However, the IC50 of pomolic acid for normal BEAS-2B cells was 80 μM. Pomolic acid also decreased colony formation of A549 cells. At 20 μM, the percentage of A549 colonies decreased to 14 % of control. The dose-dependent cytotoxicity of pomolic acid against A549 cells was mediated via induction of apoptosis and oxidative stress. Pomolic acid treatment enhanced the expression of Bax and decreased the expression of Bcl-2 in A549 cells. Moreover, pomolic acid inhibited the migration and invasion in A549 cells in a dose-dependent manner (p < 0.05). Conclusion: These results indicate the potent anticancer effect of pomolic acid against human lung cancer cells. Thus, pomolic acid has promising potential as a lead molecule for the development of chemotherapy.
The Mid-Infrared Spectra of Brown Dwarfs

We present an analysis of brown dwarf model spectra in the mid-infrared spectral region (5 - 20 microns), in anticipation of data obtained with the Space Infrared Telescope Facility. The mid-infrared spectra of brown dwarfs are in several ways simpler than those in the near-infrared and yet provide powerful diagnostics of brown dwarf atmospheric physics and chemistry, especially when combined with ground-based data. We discuss the possibility of detection of new molecular species and of the silicate cloud, predict strong observational diagnostics for non-equilibrium chemistry between CO and CH4, and N2 and NH3, and speculate on the possibility of discovering brown dwarf stratospheres.
Power Prediction of Bifacial Si PV Module with Different Reflection Conditions on Rooftop

A bifacial solar module has a structure that allows the rear electrode to be added to the existing silicon photovoltaic module structure. Thus, it can capture energy from both the front and rear sides of the module. In this paper, modeling is suggested to estimate the amount of energy generated from the rear of the bifacial photovoltaic module. After calculating the amount of irradiance from the rear side, the estimated power generation is compared with the real power output from the rear side of the module. The experiments were performed using four different environments with different albedos. The theoretical prediction of the model shows a maximum of 5% and average of 1.86% error in the measurement data. Based on the nature of the bifacial solar module, which receives additional irradiance from the rear side, this study compared the output amounts with respect to different rear environments. Recently, installation of floating Photovoltaic has been increasing. As the reflection of irradiation from the water surface occurs, the positive influence of the installation with the bifacial photovoltaic can be expected. We are confident that this research will contribute to zero energy construction by designing systems based on bifacial PV module with high performance ratio when applying solar power in a microgrid environment, which is the future energy.
Numerical analysis of a uniform flow of a rarefied gas past a sphere on the basis of the Boltzmann equation for hard-sphere molecules(Mathematical Analysis of Phenomena in Fluid and Plasma Dynamics)

A slow uniform flow of a rarefied gas past a sphere is investigated on the basis of the linearized Boltzmann equation for hard‐sphere molecules and the diffuse reflection condition. With the aid of a similarity solution, the Boltzmann equation is reduced to two simultaneous integrodifferential equations with three independent variables, which are solved numerically. The collision integral is computed efficiently by the use of a numerical collision kernel [Phys. Fluids A 1, 363 (1989)]. The velocity distribution function of the gas molecules, which has discontinuity in the gas, the density, flow velocity, and temperature fields of the gas, and the drag on the sphere are obtained accurately for the whole range of the Knudsen number. In spite of slow flow, the temperature is nonuniform (thermal polarization). From the behavior of the velocity distribution function, the kinetic transition region is clearly seen to separate into the Knudsen layer and the S layer for small Knudsen numbers.
Lightning Impulse Withstand of Natural Ester Liquid

Due to the low biodegradability of mineral oil, intense research is conducted to define alternative liquids with comparable dielectric properties. Natural ester liquids are an alternative in focus; they are used increasingly as insulating liquid in distribution and power transformers. The main advantages of natural ester liquids compared to mineral oil are their good biodegradability and mainly high flash and fire points providing better fire safety. The dielectric strength of natural ester liquids is comparable to conventional mineral oil for homogeneous field arrangements. However, many studies showed a reduced dielectric strength for highly inhomogeneous field arrangements. This study investigates at which degree of inhomogeneity differences in breakdown voltage between the two insulating liquids occur. Investigations use lightning impulses with different electrode arrangements representing different field inhomogeneity factors and different gap distances. To ensure comparisons with existing transformer geometries, investigations are application-oriented using a transformer conductor model, which is compared to other studies. Results show significant differences in breakdown voltage from an inhomogeneity factor of 0.1 (highly inhomogeneous field) depending on the gap distance. Larger electrode gaps provide a larger inhomogeneity at which differences in breakdown voltages occur.
A spectral atlas of H II galaxies in the near-infrared

Recent models show that TP-AGB stars should dominate the NIR spectra of populations 0.3 to 2 Gyr old, leaving unique signatures that can be used to detect young/intermediate stellar population in galaxies. However, no homogeneous database of star-forming galaxies is available in the NIR to fully explore these results. With this in mind, we study the NIR spectra of a sample of 23 HII and starburst galaxies, aimed at characterizing the most prominent spectral features and continuum shape in the 0.8-2.4 micron region of these objects. Spectral indices are derived for the relevant absorption lines/bands and a comparison with optical indices of the same sample available in the literature is made. We found no correlation between the optical and the NIR indexes. This is probably due to the differences in aperture between these two sets of data. That result is further supported by the absence or weakness of emission lines in the NIR for a subsample galaxies, while in the optical the emission lines are strong and clear, which means that the ionisation source in many of these galaxies is not nuclear, but circumnuclear or located in hot spots. We detected important signatures predicted for a stellar population dominated by the TP-AGBs, like CN 1.1 micron and CO 2.3 micron. In at least one galaxy (NGC 4102) the CN band at 1.4 micron was detected for the first time. We also detect TiO and ZrO bands that have never been reported before in extragalactic sources. The shape of the continuum emission is found to be strongly correlated to the presence/lack of emission lines. An observational template for the star-forming galaxies is derived to be used as a benchmark of stellar population(s) in starburst galaxies against which to compare near-IR spectroscopy of different types of galaxies, especially those with AGN activity and/or those at high-redshift.
Pruned Hurwitz numbers

We define a new Hurwitz problem which is essentially a small core of the simple Hurwitz problem. The corresponding Hurwitz numbers have simpler formulae, satisfy effective recursion relations and determine the simple Hurwitz numbers. We also apply this idea of finding a smaller simpler enumerative problem to orbifold Hurwitz numbers and Belyi Hurwitz numbers.
The Chemokines CXC, CC and C in the Pathogenesis of COVID-19 Disease and as Surrogates of Vaccine-Induced Innate and Adaptive Protective Responses

COVID-19 is one of the progressive viral pandemics that originated from East Asia. COVID-19 or SARS-CoV-2 has been shown to be associated with a chain of physio-pathological mechanisms that are basically immunological in nature. In addition, chemokines have been proposed as a subgroup of chemotactic cytokines with different activities ranging from leukocyte recruitment to injury sites, irritation, and inflammation to angiostasis and angiogenesis. Therefore, researchers have categorized the chemotactic elements into four classes, including CX3C, CXC, CC, and C, based on the location of the cysteine motifs in their structures. Considering the severe cases of COVID-19, the hyperproduction of particular chemokines occurring in lung tissue as well as pro-inflammatory cytokines significantly worsen the disease prognosis. According to the studies conducted in the field documenting the changing expression of CXC and CC chemokines in COVID-19 cases, the CC and CXC chemokines contribute to this pandemic, and their impact could reflect the development of reasonable strategies for COVID-19 management. The CC and the CXC families of chemokines are important in host immunity to viral infections and along with other biomarkers can serve as the surrogates of vaccine-induced innate and adaptive protective responses, facilitating the improvement of vaccine efficacy. Furthermore, the immunogenicity elicited by the chemokine response to adenovirus vector vaccines may constitute the basis of vaccine-induced immune thrombotic thrombocytopaenia.
Combining sport and conventional military training provides superior improvements in physical test performance

Training for both sporting and military performance is common practice within army trainee populations, although it is currently unknown what effect this combination of training methods may have on the physical attributes required for overall physical preparedness. This study examined the effects of sport-specific training on general fitness in a professional military population. Four hundred and twenty-three Greek male army cadets completed a 12-week training regimen involving standard physical training (callisthenics, strength and endurance running exercises) and either general military training (GMT) or sport military training (SMT). A series of physical tests took place before and after the training period: a mile run, pull-ups, 50 m swim and an obstacle course run. Both the GMT and SMT groups showed significant (p < 0.001) improvements in all physical tests. However, the SMT group produced significantly greater improvements in all four tests (pull-ups [p < 0.001], 50 m swim [p < 0.05], obstacle course [p < 0.01] and mile run [p < 0.01]) compared to the GMT group. Furthermore, different types of SMT (e.g. rock climbing and track sprinting) achieved greater improvements (p < 0.001–0.01) in certain physical tests when compared to other forms of SMT (e.g. Pankration, Fencing). These results indicate that cadets undertaking concurrent participation in general and sport military training are overall better prepared for physical performance than their counterparts who undertake only general military training. Military conditioning personnel should be aware of the positive interplay between general and sports specific training in forming a preparation strategy designed for physical performance.
Multiteam Systems in Long Duration Exploration Missions: A Qualitative Analysis of Key Characteristics and Challenges

Given the unprecedented environment of long duration space exploration (LDSE), success simply cannot occur without the coordinated efforts of multiple teams, both in flight and on the ground. These multiteam systems (MTSs) are needed to achieve the complex and dynamic tasks of spaceflight missions that will be longer and more uncertain than any previously experienced. Accordingly, research is limited in terms of how to best coordinate these teams and their dynamics—and in particular, how to best prepare LDSE teams to work across time and space effectively. To begin to address these critical questions systematically, qualitative data was extracted from a series of ten interviews with experts in spaceflight and long duration analog environments. Using thematic analysis techniques, we identified several consistent themes for affective, behavioral, and cognitive elements of teamwork occurring within and between teams. We examine each of these in detail, to identify the dynamics of what is currently known and where research needs to go to provide guidance for spaceflight organizations as well as others attempting to successfully implement MTSs in novel, complex environments.
Pediatric Sedation/Anesthesia for MRI: Results From the Pediatric Sedation Research Consortium

Magnetic resonance imaging (MRI) is the most common imaging procedure requiring sedation/anesthesia in children. Understanding adverse events associated with sedation/anesthesia is important in making decisions regarding MRI vs. other imaging modalities. No large studies have evaluated the practice of pediatric sedation/anesthesia for MRI by a variety of pediatric specialists.
Prefabrication in the Australian context

Australia actually has a long history with prefabricated building since its early settlement days. However, methods of prefabrication have, until the past decade, been relatively few and almost nonexistent with the exception of relocatable school building or portables. The revival of interest in prefabricated building has been quite recent, involving a few selective construction companies, and the interpretation of prefabrication has mainly resulted in a ‘volumetric’ product as the solution. In response to this, first the paper describes the profile of prefabrication in Australia, and then addresses a pathway for the processes and methods to pre-fabrication based on the identified challenges in Australia. This paper presents these ideas and discusses the up and coming directions of prefabrication in Australia.
MWCNTs-CTAB and HFs-Lac Nanocomposite-Modified Glassy Carbon Electrode for Rutin Determination

Rutin is a flavonoid glycoside compound, which is mainly transported via the blood circulation system in the human body. The monitoring of the blood concentration of rutin is of great significance in many fields such as pharmacology and pharmacokinetics. In this work, a biosensor based on multi-walled carbon nanotubes (MWCNTs), cetyltrimethylammonium bromide (CTAB), hydroxyl fullerenes (HFs), and laccase (Lac) nanocomposite-modified glassy carbon electrodes was constructed. The modified materials were characterized with a transmission electron microscope (TEM), cyclic voltammograms (CV), and electrochemical impedance spectroscopy (EIS). CTAB is used to disperse MWCNTs and improve hydrophilicity and biocompatibility of MWCNTs, while the use of Lac can enhance the oxidation of catechol structure in rutin, thus significantly improving the sensitivity and selectivity of the modified electrode. Linear sweep voltammetry (LSV) studies showed that the determination linear ranges of rutin were 0.1 µmol L−1 to 2 µmol L−1 and 2 µmol L−1 to 11 µmol L−1, with the determination limits of 30 nmol L−1 and 95.5 nmol L−1, respectively. The proposed biosensor can be used to detect rutin tablets and serum samples with high recovery, which indicates a good accuracy of this method, and the results are consistent with those measured by the traditional ultra-high performance liquid chromatography (UHPLC) method. Hence, this biosensor has potential practical application value in rutin drug quality testing and clinical blood drug concentration monitoring.
Evaluation of Inverted-Pendulum-with-Rigid-Legs Walking Locomotion Models for Civil Engineering Applications

Bipedal models for walkers, originally developed in the research field of biomechanics, have been identified as potential candidates for modelling pedestrians in structural engineering applications. These models provide insight into both the kinetics and kinematics of walking locomotion and are considered to have a significant potential to improve the vibration serviceability assessment of civil engineering structures. Despite this notion, the ability of the bipedal models to represent the key features of the walking gait and natural variability within the pedestrian population are still under-researched. This paper critically evaluates the performance of two bipedal models with rigid legs to realistically both reproduce key features of an individual pedestrian’s walking gait and represent a wide range of individuals. The evaluation is performed for walking on a rigid, rather than vibrating, structure due to the availability of experimental data and expectation that successful modelling on rigid surfaces is a necessary condition for progressing towards modelling on the vibrating structures. Ready-to-use equations are provided and the ability of the models to represent the kinematics and kinetics of individual pedestrians as well as the inter-subject variability typical of the human population is critically evaluated. It was found that the two models could generate realistic combinations of the gait parameters and their correlations, but are less successful in reproducing genuine kinetic and kinematics profiles.
11β-HSD as a New Target in Pharmacotherapy of Metabolic Diseases

Glucocorticoids (GCs), which are secreted by the adrenal cortex, are important regulators in the metabolism of carbohydrates, lipids, and proteins. For the proper functioning of the body, strict control of their release is necessary, as increased GCs levels may contribute to the development of obesity, type 2 diabetes mellitus, hypertension, cardiovascular diseases, and other pathological conditions contributing to the development of metabolic syndrome. 11β-hydroxysteroid dehydrogenase type I (11β-HSD1) locally controls the availability of the active glucocorticoid, namely cortisol and corticosterone, for the glucocorticoid receptor. Therefore, the participation of 11β-HSD1 in the development of metabolic diseases makes both this enzyme and its inhibitors attractive targets in the pharmacotherapy of the above-mentioned diseases.