Miracle-dz/UniFAR-FTUs huggingface dataset:
The Perspective of Vitamin D on suPAR-Related AKI in COVID-19

The coronavirus disease 2019 (COVID-19) pandemic has claimed the lives of millions of people around the world. Severe vitamin D deficiency can increase the risk of death in people with COVID-19. There is growing evidence that acute kidney injury (AKI) is common in COVID-19 patients and is associated with poorer clinical outcomes. The kidney effects of SARS-CoV-2 are directly mediated by angiotensin 2-converting enzyme (ACE2) receptors. AKI is also caused by indirect causes such as the hypercoagulable state and microvascular thrombosis. The increased release of soluble urokinase-type plasminogen activator receptor (suPAR) from immature myeloid cells reduces plasminogen activation by the competitive inhibition of urokinase-type plasminogen activator, which results in low plasmin levels and a fibrinolytic state in COVID-19. Frequent hypercoagulability in critically ill patients with COVID-19 may exacerbate the severity of thrombosis. Versican expression in proximal tubular cells leads to the proliferation of interstitial fibroblasts through the C3a and suPAR pathways. Vitamin D attenuates the local expression of podocyte uPAR and decreases elevated circulating suPAR levels caused by systemic inflammation. This decrease preserves the function and structure of the glomerular barrier, thereby maintaining renal function. The attenuated hyperinflammatory state reduces complement activation, resulting in lower serum C3a levels. Vitamin D can also protect against COVID-19 by modulating innate and adaptive immunity, increasing ACE2 expression, and inhibiting the renin–angiotensin–aldosterone system. We hypothesized that by reducing suPAR levels, appropriate vitamin D supplementation could prevent the progression and reduce the severity of AKI in COVID-19 patients, although the data available require further elucidation.
The Management Mode of College Students' Mental Health Based on Wireless Sensor Network

: In today's society, there are more and more psychological problems among college students, and the main source is no longer purely from academic pressure, society, parents and other aspects. As a result, more and more college students are facing mental health problems, and the lack of better mediation of mental health problems has exacerbated this phenomenon. The purpose of this article is to explore the management model of college students' mental health. For this reason, this paper proposes to monitor the mental health of college students through the use of wireless sensor networks. A trust model is established for analysis, and the sensor node structure is re-arranged to ensure the stable operation of the wireless sensor network and the reliability of the monitoring results. At the same time, experiments are designed to explore the mental health of college students. The experimental results of this paper show that the newly deployed wireless sensor network can increase the monitoring efficiency of the existing sensor network by 31%, which can greatly improve the monitoring of college students' mental health and help them solve related psychological problems.
Cuban stingless bee livestock exhibit specialized floral resource use: a palynological study on honey samples from Matanzas and Mayabeque provinces

The knowledge of the different plant species that make up the feeding diet of animals is highly important to develop more efficient strategies. This research aimed to characterize the food potential available for the Cuban stingless bee livestock of the Matanzas and Mayabeque provinces. Palynological analysis was done using 60 g of pollen from sealed pots and 80 mL of honey from the ten randomly selected beehives (five in each province). The results showed that in the honey collected in Matanzas province, the most represented family was Amaranthaceae, followed by Myrtaceae and Fabaceae. Meanwhile, for Mayabeque, the most represented ones were the families Fabaceae and Myrtaceae. Regarding the stingless bee pollen of Matanzas provenance, the family Fabaceae prevailed, followed by Burseraceae and Myrtaceae. The pollen corresponding to Mayabeque coincided in showing Fabaceae as the most representative. In addition, pollen grains of small size (from 10 to 25 µm) were collected, with a marked representation of the pollen type of Mimosa pudica in the Mayabeque honey. It was concluded that the Cuban stingless bee livestock of the Matanzas and Mayabeque provinces had a specialist feeding behavior because a low number of plant taxa made up its diet.
The Impact of Colleague Suicide and the Current State of Postvention Guidance for Affected Co-Workers: A Critical Integrative Review

People bereaved by suicide are affected psychologically and physically and may be at greater risk of taking their own lives. Whilst researchers have explored the impact of suicide on family members and friends, the area of colleague suicide has been neglected and postvention guidance for supporting surviving colleagues is often poorly developed. This critical integrative review explored the impact of colleague suicide on surviving co-workers and reviewed postvention guidance for workplaces. Systematic searches found 17 articles that met the inclusion criteria. Articles were appraised for quality and extracted data were analysed using a thematic network method. Article quality was moderate. Two global themes were developed: impact of a colleague suicide comprised themes of ‘suicide loss in the workplace’; ‘professional identities and workplace roles’; ‘perceptions of professional uniqueness’; and ‘professional abandonment and silencing’. Postvention following a colleague suicide comprised ‘individualised responses’; ‘the dual function of stigma’; and ‘complex pressure on managers’. A unifying global network ‘after a colleague suicide’ describes the relationships between all themes. A series of disconnects between existing postvention guidance and the needs of impacted workers are discussed. This review demonstrates the need for robust, systemic postvention for colleagues impacted by the complex issue of colleague suicide.
Forced Oscillation of nth-Order Functional Differential Equations

Abstract In this paper we investigate the oscillation of forced functional differential equations x ( n ) t + a t f x q t = e t , when the forcing term e(t) is not required to be the nth derivative of an oscillatory function. Some new oscillatory criteria are given. We also apply our technique to the forced neutral differential equation of the form x t + cx t − τ ( n ) + a t x t + b t x t − τ = e t + c t f 1 x t + d t f 2 x t − τ , where xf1(x) > 0 and xf2(x) > 0 for x ≠ 0; n ≥ 1; τ, δ are nonnegative constants; a(t) > 0; b(t) > 0; c(t) > 0; d(t) > 0; which includes the special case f1(x) = |x|λ sgn x, f2(x) = |x|θ sgn x, λ ≠ 1 and θ ≠ 1.
Output feedback control of a class of feedforward nonlinear systems in the presence of sensor noise

We propose an output feedback controller for a class of feedforward nonlinear systems under sensor noise. The sensor noise is any signal whose DC component is finite, which covers not only deterministic signals but also random signals including many practical noises. We introduce a notion of virtual state, then propose a measurement output feedback controller that utilizes a gain scaling factor. The gain scaling factor is commonly employed by the observer and controller. Through analysis, we show that all system states and output remain to be bounded in the presence of sensor noise, and the bound of states except output can be made arbitrarily small. Moreover, if the DC component of sensor noise is zero, the ultimate bound of the states and output can be made arbitrarily small by increasing the gain scaling factor in the presence of sensor noise. Copyright © 2013 John Wiley & Sons, Ltd.
Standardization of Epidemiological Surveillance of Invasive Group A Streptococcal Infections

Abstract Invasive group A streptococcal (Strep A) infections occur when Streptococcus pyogenes, also known as beta-hemolytic group A Streptococcus, invades a normally sterile site in the body. This article provides guidelines for establishing surveillance for invasive Strep A infections. The primary objective of invasive Strep A surveillance is to monitor trends in rates of infection and determine the demographic and clinical characteristics of patients with laboratory-confirmed invasive Strep A infection, the age- and sex-specific incidence in the population of a defined geographic area, trends in risk factors, and the mortality rates and rates of nonfatal sequelae caused by invasive Strep A infections. This article includes clinical descriptions followed by case definitions, based on clinical and laboratory evidence, and case classifications (confirmed or probable, if applicable) for invasive Strep A infections and for 3 Strep A syndromes: streptococcal toxic shock syndrome, necrotizing fasciitis, and pregnancy-associated Strep A infection. Considerations of the type of surveillance are also presented, noting that most people who have invasive Strep A infections will present to hospital and that invasive Strep A is a notifiable disease in some countries. Minimal surveillance necessary for invasive Strep A infection is facility-based, passive surveillance. A resource-intensive but more informative approach is active case finding of laboratory-confirmed Strep A invasive infections among a large (eg, state-wide) and well defined population. Participant eligibility, surveillance population, and additional surveillance components such as the use of International Classification of Disease diagnosis codes, follow-up, period of surveillance, seasonality, and sample size are discussed. Finally, the core data elements to be collected on case report forms are presented.
Normothermic Ex Vivo Liver Platform Using Porcine Slaughterhouse Livers for Disease Modeling

Metabolic and toxic liver disorders, such as fatty liver disease (steatosis) and drug-induced liver injury, are highly prevalent and potentially life-threatening. To allow for the study of these disorders from the early stages onward, without using experimental animals, we collected porcine livers in a slaughterhouse and perfused these livers normothermically. With our simplified protocol, the perfused slaughterhouse livers remained viable and functional over five hours of perfusion, as shown by hemodynamics, bile production, indocyanine green clearance, ammonia metabolism, gene expression and histology. As a proof-of-concept to study liver disorders, we show that an infusion of free fatty acids and acetaminophen results in early biochemical signs of liver damage, including reduced functionality. In conclusion, the present platform offers an accessible system to perform research in a functional, relevant large animal model while avoiding using experimental animals. With further improvements to the model, prolonged exposure could make this model a versatile tool for studying liver diseases and potential treatments.
Identifying resilience-promoting factors for refugee survivors of torture.

INTRODUCTION There are 1.3 million refugee survivors of torture living in the United States today. An existing body of research with refugees has largely examined mental health, but few of these studies focused on resilience. OBJECTIVE Using a clinical sample of refugee survivors of torture, we tested the resiliencepromoting factors of community engagement, employment, English fluency, and psychological flexibility. We conducted moderation and mediation analyses to investigate how these resilience-promoting factors impact the torture-mental health relationship. RESULTS Torture severity had significant positive associations with all mental health symptoms including PTSD (post-traumatic stress disorder), depression, and anxiety. Conversely, psychological flexibility had significant negative associations with all mental health symptoms. Additionally, psychological flexibility was a significant mediator of the torture-mental health relationship, highlighting its potential as a causal mechanism between torture and mental health. This evidence suggested that experiencing greater torture severity led to greater mental health problems in part via difficulties in psychological flexibility. Separately, English fluency and employment status were negatively correlated with mental health symptoms. CONCLUSION The findings from this study identified potentially resilience-promoting factors for refugee survivors of torture and contributed to both research and clinical insights in better serving this vulnerable population.
Strategic Planning of Regional Tourism Information System of Morotai Island Regency using Ward and Peppard Framework

The tourism development program in Indonesia is not central but decentralized so that each autonomous region has the authority to determine the direction of policies and strategies for developing tourism potential in their respective areas. In the context of the Morotai Islands regency, an integrated regional tourism information system has not been designed to control and synchronize stakeholders' interests and optimize the marketing of regional tourist destinations. Considering this, this study offers the Ward and Peppard framework for the strategic design of Sistem Informasi Pariwisata Daerah (SIPARDA) as a website-based application that can be used for data collection and monitoring of regional tourism resources as well as tourism destination development programs in Morotai Island Regency. This study shows that the identification of external and internal conditions of the business environment is not limited to the Value Chain approach and Porter's Five Forces Model but also the Tourism Area Life Cycle and Irritation Index to understand the context of regional tourism-related to tourism resources both attractions, accommodation, amenities, and accessibility, as well as the level of acceptance of the Morotai people towards tourism development programs. Furthermore, identifying the current internal and external conditions of information systems or information technology in the portfolio application is analyzed based on Strenght, Weaknesses, Opportunities, and Threats (SWOT) to provide recommendations for future application portfolios. The results of this study recommend the Regional Tourism Information System known as Sistem Informasi Pariwisata Daerah (SIPARDA) as a portfolio future application that needs to be prioritized to optimize the function of monitoring tourism development in the Morotai Island Regency.
The impact of spinal fusion of adolescent idiopathic scoliosis in Salah (Islamic Prayer) movement: a case-control study

Background: Corrective spine surgery is widely accepted for treating severe adolescent idiopathic scoliosis (AIS). Postoperative spinal range of motion (ROM) could be affected after such surgery. In certain populations, such as Muslims, this ROM change can impact daily life, as it may affect the five-times-a-day prayer (Salah). This study aims to assess the influence of spinal fusion (SF) in Adolescent Idiopathic Scoliosis (AIS) during the daily Islamic prayer (Salah). Methods: SF-AIS patients were videoed while performing Salah prayer. The kinematic documentation was assessed and compared to Salah movements of a control group of age-matched Muslim AIS patients, who had not had surgery. The prayer quality changes were subjectively classified into improved, no change/remained, and worsened, according to the Global Perceived Effect (GPE). Functional outcome and pain were assessed by the Scoliosis Research Society Questionnaire Version 30 (SRS-30). Results: Thirty-nine women and five men (mean age±SD: 14.8±2.3 years) met the inclusion criteria, and unoperated AIS patients were used as control (twenty-two women, mean age±SD: 15.32±1.43 years). The prostrations ROM of the SF-AIS group differed significantly from the control group (p<0.05). The GPE of the prayer movement showed improvement in 36.4%, no change in 59.1%, and worsening in 4.5% of the SF-AIS patients. The worsened group had a significantly lower bowing ROM and higher prostrations ROM compared to all groups of prayer quality changes (p<0.05). SRS-30 scores showed good outcomes (function 4.0±0.2, pain 4.2±0.5), along with the overall bowing ROM and prostrations ROM (84.2±12.0o and 53.4±9.6o, respectively). Moreover, a significant moderate positive correlation between the bowing ROM and pain (r=0.417, p=0.007) was also found. Conclusion: Spinal fusion positively affects AIS Islamic patients in maintaining their daily Salah movement, ROM and prayer quality. Prayer quality assessment should be given extra attention as an adjuvant of the SRS-30 questionnaire to evaluate Muslim patients.
PRESERVATION AND HOST PREFERENCES OF LATE FRASNIAN (LATE DEVONIAN) SKELETOBIONTS IN THE APPALACHIAN FORELAND BASIN, USA

Abstract: Skeletobionts, organisms that attach to or bore into the skeleton of a host, provide a useful system to observe biological interactions over geological timescales. We examined skeletobionts on brachiopod hosts from a stratigraphic section in western New York State that spanned the Lower Kellwasser and Upper Kellwasser events, the two pulses of the Frasnian–Famennian (Late Devonian) mass extinction. The fossils are largely preserved as molds, and even endoskeletobiont borings are often visible with minimal preparation. At least seven major groups of skeletobiont are present including microconchids, stenolaemate and ctenostome bryozoans, hederelloids, and various borings attributed to sponges. The total frequency of skeletobiosis declined significantly across the first extinction pulse (Lower Kellwasser Event), and relative abundance patterns shifted, although the biotic and/or abiotic drivers of these changes require further study. Multivariable logistic regression indicates that large host body size was a strong and consistent predictor of skeletobiosis. Endoskeletobionts were more common in coarser lithologies, reflecting either an ecological preference for sands over muds or a bias against preservation in mudstones. Endoskeletobionts were also more common on ribbed/costate host shells.
The Reliability and Predictive Validity of Sense of Coherence Scale for American Survivors of Gender-Based Violence

This study investigated the reliability and predictive validity of the Sense of Coherence (SOC) scale for 299 American survivors of gender-based violence (GBV). First, confirmatory factor analysis examined the construct validity of the SOC-13. Then, relationships between SOC and clinical scales were examined. Confirmatory factor analysis supported the 3-factor solution, and Cronbach's alpha reliability values for comprehensibility, manageability, and meaningfulness subscales and total score of SOC-13 were: . 62, . 53, . 65, and . 81, respectively. Multiple regression revealed that age, posttraumatic growth, depression, and posttraumatic stress scores explained 53% of the variance of SOC scores. We interpret this to suggest that SOC is a protective factor in GBV, especially in younger women. Clinical implications are suggested.
Industrial Production of Post-industrial Products: How Interactive Visualizations Miss Their Potential as a Journalistic Form of Knowledge

ABSTRACT Journalistic interactive visualizations (JIVs) – such as scrollytellings, interactive infographics, and clickable data visualizations – have an epistemic potential to efficiently and intricately mediate rich journalistic knowledge. In practice, however, they usually mediate and oversimplify limited knowledge. To understand why and where, across the production line, JIVs lose their epistemic potential, we map the production process of JIVs in three leading Israeli news organizations based on a combination of in-depth and reconstruction interviews with 22 JIV producers. Findings point to nine prominent bifurcations, where the production course can shape JIVs so that they mediate rich and intricate or limited and simplistic knowledge. Overall, these findings reflect a misfit between an “industrial” production process and a “post-industrial” news product.
Response to Comment (arXiv:1506.02787v1) on Selective Interface Control of Order Parameters in Complex Oxides

In response to Lu et al, (arXiv:1506.02787v1), here we present a detailed writeup concerning the questions raised in their comment on our eprint (arXiv:1505.07451). The key question raised by Lu et al was if the bulk-like charge ordered state becomes indetectable with resonant scattering due to ultrathin film thickness. In this reply, we first detail the relation of our work to past work on the same compound by Staub et al to demonstrate that the presented data are indeed sufficient to support our claims of no charge order on ultra thin films of NdNiO3 (NNO) on NdGaO3 (NGO). Further, we demonstrate that if a well defined charge ordered phase exists in ultra thin films, it is indeed resolvable such as that in EuNiO3 (ENO).
Different Gut Microbiomes of Developmental Stages of Field-Collected Native and Invasive Western Bean Cutworm, Striacosta albicosta, in Western Nebraska

While insects harbor gut microbial associates that perform various functions for the host, lepidopterans have not been considered as prime examples of having such relationships. The western bean cutworm, Striacosta albicosta (Lepidoptera: Noctuidae), is native to North America and has historically been a significant corn pest in its western distribution. It is currently expanding eastwards and is invasive in these new regions. Using 16S rRNA gene sequencing data, this study focused on characterizing the microbiota associated with field-collected eggs, larvae, adults, and host plant materials of S. albicosta in its native range. The diversity of microbiomes varied significantly among S. albicosta eggs, larvae, adults, and the host plant materials. Microbial diversity was highest in adult stages relative to other insect stages. Furthermore, S. albicosta eggs, larvae, and adults harbored very distinct microbial communities, indicative of stage-specific microbiomes possibly performing different functions. Bacterial taxa underscoring these differences in composition identified four phyla and thirty families across samples. Members of the Firmicutes (Unassigned Lactobacillales), Proteobacteria (Pseudomonadaceae and Moraxellaceae), Bacteroidota (Weeksellaceae), and Chloroflexi dominated across all developmental stages. In addition, cellulose-degrading Lactobacillales (phylum: Firmicutes) dominated larval microbiomes, indicative of larval plant diet. This taxon was comparatively negligible in eggs and adults. Members of Proteobacteria dominated egg and host leaf microbiomes, while members of Bacteroidota dominated nectar-feeding adult gut microbiomes. Our results suggest a possible diet-dependent stage-specific microbiome composition and the potential for using stage-specific microbes as potential biological control tools against this important pest moving forward.
Open Growth Habit in Summer Squash1

Summer squash cultivars (Cucurbita pepo L.) of the Zucchini type were classified on a scale of 1 (open) to 5 (dense growth habit). A trial with 5 cultivars indicated that yield is not dependent on heavy foliage, and that picking time required per unit of crop is much less with open growth habit. An inheritance study was inconclusive because of problems in progeny plant classification. It appears that growth habit is a complex of several characteristics, and as such, is inherited in a multigenic manner.