Miracle-dz/UniFAR-FTUs huggingface dataset:
Characteristics of Computed Tomography for Identifying Patients at High Risk of Endogenous Endophthalmitis Due to Klebsiella pneumoniae-Related Pyogenic Liver Abscess

Endogenous endophthalmitis (EE) associated with Klebsiella pneumoniae (K. pneumoniae)-related pyogenic liver abscess (PLA) is one of the fatal complications of PLA and leads to loss of vision. Early diagnosis and treatment are important to save the patient’s vision. We investigated the characteristics of computed tomography (CT) in EE associated with K. pneumoniae-related PLA for the identification of the predictors of EE, in order to facilitate early diagnosis. A total of 274 patients diagnosed with K. pneumoniae-related PLA, including 15 patients with EE, were identified between January 2005 and December 2019. The clinical (age, gender, and underlying disease) and radiologic (the location, size, and number of abscesses) features were reviewed. In addition, the involvement of the adjacent vessels, such as the hepatic vein and portal vein, was carefully reviewed. A comparative analysis was performed between the EE and non-EE groups. Uni- and multivariate logistic regression analyses were used to identify the predictors of EE. Diabetes mellitus (DM), the involvement of the left or both hepatic lobes, and the adjacent vessels on the CT were significantly more frequent than those in the non-EE group (p < 0.05 in all), and they were the significant predictors of EE in the logistic regression analyses. In patients with K. pneumoniae-related PLA, the CT findings, such as the locations of the abscess (i.e., left or both lobes) and the involvement of the adjacent vessels, should be considered in addition to the ocular symptoms for an early diagnosis of EE.
Deep Learning Beehive Monitoring System for Early Detection of the Varroa Mite

One of the most critical causes of colony collapse disorder in beekeeping is caused by the Varroa mite. This paper presents an embedded camera module supported by a deep learning algorithm for the process of early detecting of Varroa infestations. This is achieved using a deep learning algorithm that tries to identify bees inside the brood frames carrying the mite in real-time. The end-node device camera module is placed inside the brood box. It is equipped with offline detection in remote areas of limited network coverage or online imagery data transmission and mite detection over the cloud. The proposed deep learning algorithm uses a deep learning network for bee object detection and an image processing step to identify the mite on the previously detected objects. Finally, the authors present their proof of concept experimentation of their approach that can offer a total bee and varroa detection accuracy of close to 70%. The authors present in detail and discuss their experimental results.
Impact of Phacoemulsification Cataract Surgery to Number of Corneal Endothelial Cells: A Descriptive Study

The main optical structure of the eyes is the lens and corneal because lens with the cornea, focuses image of the visual world onto the retina. Both of the main optical structure is affected by age, it affects the corneal endothelial cells and transparency of the lens. By aging the corneal endothelial cells decrease and the lens loses its transparency then the cataract appears [1,2]. it is known that cataract surgery effecting the corneal endothelial cells number. The surgery will be decreasing the corneal endothelial cells number. The severity to which endothelium is affected depends on many factors, such as phacoemulsification time and energy, surgical technique, anterior chamber depth, and use of ophthalmic viscoelastic devices (OVDs) [3]. A total of 52 people with cataracts were enrolled in this descriptive investigation. The study is included 52 eyes. Ages ranged from 43-77 years, with a mean age of 57,7 years. From this study 59,6% were men and the rest are women, which 79% were diagnosed with immature cataract, and 21% were diagnosed with mature cataract. It was found that 86,5% of eyes experienced a decrease in the number of corneal endothelial cells after cataract phacoemulsification surgery. The mean of corneal endothelial density pre surgery is 3126 cells/mm2 ± 246,1 and the mean of corneal endothelial density post-surgery is 3029 cells/mm2. The range of surgery time is 6-30 minutes. With the mean time of surgery 13,7 ± 5,8 minutes. From 52 eyes there are 45 eyes with corneal endothelial cells loss 7 days after surgery, with the mean of corneal endothelial cells loss after cataract phacoemulsification surgery are 152,3 ± 68 cells/mm2, the percentage mean was 6%, and we found decreasing in central corneal thickness, corneal endothelium density, hexagonality and increasing coefficient of variety.
Is there a welfare trap? Duration dependence in social assistance recipiency among young Finns

The probability of social assistance exit decreasing over time is called negative duration dependence. This is one of the most debated aspects of social assistance receipt. This study analyses duration dependence among young adults in Finland and aims to show how social assistance receipt per se affects the likelihood of exiting social assistance. It also examines whether parental recipiency is associated with duration dependence. While the intergenerational transmission of social assistance has received extensive research attention, there is a scarcity of evidence on whether parental recipiency is associated with social assistance exits and duration effects. This study uses full monthly history of social assistance receipt between the ages of 19 and 29 years. The analyses are based on Finnish register data and conducted using discrete-time event-history models (pooled logistic, random-effect logistic and fixed-effect logistic). The findings indicate that controlling for all time-invariant characteristics significantly reduces but does not completely remove duration dependence among young adults. They also show that those whose parents received social assistance are less likely to exit social assistance. In models controlling for all time-invariant characteristics, parental social assistance receipt is also linked with stronger duration dependence. The implications of these findings are discussed.
Determinants and Trends of Health Facility Delivery in Bangladesh: A Hierarchical Modeling Approach

Background Most maternal deaths occur during childbirth and after childbirth. This study was aimed at determining the trends of health facilities during delivery in Bangladesh, as well as their influencing factors. Methods This study used secondary data from three Bangladesh Multiple Indicator Cluster Surveys (MICSs) in 2006, 2012–13, and 2019. The study's target sample was those women who gave birth in the last two years of the survey. A two-level logistic regression was applied to determine the effects on health facility delivery separately in these two survey points (MICSs 2012–13 and 2019). Results The results show that the delivery of health facilities has increased by almost 37.4% in Bangladesh, from 16% in 2006 to 53.4% in 2019. The results of two-level logistic regression show that the total variation in health facility delivery across the community has decreased over recent years. After adding community variables, various individual-level factors such as women with secondary education (OR = 0.55 in 2012-13 vs. OR =0.60 in 2019), women from middle wealth status (OR = 0.49 in 2012-13 vs. OR = 0.65 in 2019), religion, and child ever born showed a strong relationship with health facility delivery in both survey years. At the community level, residents showed significant association only in the 2012-13 survey and indicated a 43% (OR = 1.43 for 2012-13) greater availability of health facilities in urban residences than in rural residences. Using media showed a highly significant connection with health facility delivery in both years as well as an increasing trend over the years in Bangladesh (OR = 1.19 in 2012-13 vs. OR = 1.38 in 2019). However, division, prenatal care, and skilled services all contribute greatly to increasing the delivery of health facilities in Bangladesh. Conclusions The results of this study suggest that policymakers need to pay attention to individual and community-level factors, especially women's education, poverty reduction, and adequate prenatal care provided by well-trained caregivers.
A Theoretical Investigation on the Physical Properties of Zirconium Trichalcogenides, ZrS3, ZrSe3 and ZrTe3 Monolayers

In a recent advance, zirconium triselenide (ZrSe3) nanosheets with anisotropic and strain-tunable excitonic response were experimentally fabricated. Motivated by the aforementioned progress, we conduct first-principle calculations to explore the structural, dynamic, Raman response, electronic, single-layer exfoliation energies, and mechanical features of the ZrX3 (X = S, Se, Te) monolayers. Acquired phonon dispersion relations reveal the dynamical stability of the ZrX3 (X = S, Se, Te) monolayers. In order to isolate single-layer crystals from bulk counterparts, exfoliation energies of 0.32, 0.37, and 0.4 J/m2 are predicted for the isolation of ZrS3, ZrSe3, and ZrTe3 monolayers, which are comparable to those of graphene. ZrS3 and ZrSe3 monolayers are found to be indirect gap semiconductors, with HSE06 band gaps of 1.93 and 1.01 eV, whereas the ZrTe3 monolayer yields a metallic character. It is shown that the ZrX3 nanosheets are relatively strong, but with highly anisotropic mechanical responses. This work provides a useful vision concerning the critical physical properties of ZrX3 (X = S, Se, Te) nanosheets.
Efficacy of Unilateral and Bilateral Parietal Transcranial Direct Current Stimulation on Right Hemispheric Stroke Patients With Neglect Symptoms: A Proof-of-Principle Study

Different transcranial direct current stimulation (tDCS) protocols have been tested to improve visuospatial neglect (VSN). So far, methodological heterogenity limits reliable conclusions about optimal stimualtion set-up. With this proof-of-principle study behavioral effects of two promising (uni- vs. bilateral) stimulation protocols were directly compared to gain more data for an appropriate tDCS protocol in subacute neglect patients. Notably, each tDCS set-up was combined with an identical sham condition to improve comparability. In a double-blind sham-controlled cross-over study 11 subacute post-stroke neglect patients received 20 minutes or 30 seconds (sham) tDCS (2 mA, 0.8 A/m2) parallel to neglect therapy randomized in unilateral (anode-reference: P4-Fp2 10-20 electroencephalography [EEG] system) and bilateral manner (anode-cathode: P4-P3) and 48h wash-out in-between. Before and immediately after stimulation performance were measured in cancellation task (bell test), and line bisection (deviation error). Significant difference between active and assigned sham condition was found in line bisection but not cancellation task. Particularly, deviation error was reduced after bilateral tDCS (hedges g* = 0.6) compared to bilateral sham, no such advantage were obtained for unilateral stimulation (hedges g* = 0.2). Using a direct comparison approach findings add further evidence that stimulating both hemispheres (bilateral) is superior in alleviating VSN symptoms than unilateral stimulation in subacute neglect.
Safety Messaging Boosts Parental Vaccination Intention for Children Ages 5–11

The COVID-19 vaccination rate among children ages 5–11 is low in the U.S., with parental vaccine hesitancy being the primary cause. Current work suggests that safety and side effect concerns are the primary reasons for such vaccine hesitancy. This study explores whether this hesitancy can be mitigated with information interventions. Based on theories of health decision making and persuasion, we designed four information interventions with varying contents and lengths. We wrote two messages on vaccine safety (a detailed safety-long message and a succinct safety-short message), explaining the vaccine’s lower dosage, low rate of side effects, and the rigorous approval process. We also had two messages on protection effects (protect-family, protect-child). We combined these four messages with a vaccine-irrelevant control message and compared their effects on parental vaccine intention. We measured the parental vaccination intention using a 0–6 Likert scale question. Among the four intervention groups, we found that the short version of the safety message increased the average vaccination intention by over 1 point compared to the control arm, while the other three interventions failed to show significance. Specifically, these effects are particularly pronounced (around 2 points) for Republican parents who had a much lower initial intention to vaccinate their children. Our study highlights the importance of concise and to-the-point information rendering in promoting public health activities and therefore has important policy implications for raising vaccination intentions among parents, especially those leaning towards more conservative political affiliation.
PLC-Based Integrated Refractive Index Sensor Probe with Partially Exposed Waveguide

This paper proposes a simple, high-efficiency refractive index (RI) sensor, with a structure based on the planar lightwave circuit (PLC) probe type. The optical sensor has a 1 × 2 splitter structure with reference and sensing channels, each consisting of a U-shaped waveguide structure that is configured by connecting C bends. This design allows for the sensor device to have a probe structure wherein the surface interconnected with activity devices (i.e., an optical source and optical detector) is placed on one side. The reference channel is bent with a minimum optical loss, and the sensing channel has a bent structure, involving a C-bend waveguide with a maximum loss. The C-bend waveguide with a maximum loss is conformally aligned to have a trench structure with the same bending radius, designed to selectively expose the sidewall of the core layer. The local index contrast varies depending on the material in contact with the trench, resulting in a change in the optical output power of the waveguide. The sensitivity of the proposed sensor was 0 and 2070 μW/refractive index unit (RIU) for the reference and sensing channels, respectively, as the RI changed from 1.385 to 1.445 at a 1550 nm wavelength. These results suggest that the proposed structure enables efficient RI measurement through the use of a simple dip-type method.
Algunos problemas de análisis sobre cúspides exteriores

In this thesis we study several problems of analysis on domains with external cusps. Mainly: the density of smooth functions on Sobolev spaces, the extension problem and Korn’s inequality. It is known that many classical analysis results on standard Sobolev spaces, which are necessary for the study of partial differential equations and for approximating their solutions using numerical methods, do not hold on singular domains, such as external cusps. Hence, it is necessary to work with weighted Sobolev spaces, where the weights are taken in a way that somehow compensates the singularity of the domain. The different notions of external cusp that we handle avoid any precise description of the domain’s boundary, even when they impose some restrictions. In the first place, we introduce the concept of normal cusp, which definition is based on the Whitney decomposition of the domain, and includes a sectional unifomity property that establishes some local regularity on the boundary. This notion allows us to prove the following results: • The density of smooth functions up to the boundary of the domain, in the Sobolev space W(Ω). • Extension theorems where we build operators of the form E : W(Ω) −→ W σ (R), being σ a proper weight. Afterwards, we introduce the notions of chains of rectangles and chains of quasi-rectangles. Chains of quasi-rectangles allow us to define a very general class of domains, that includes normal cusps, but admits more relaxed conditions on the boundary. For these chains, we prove: • Unweighted Poincaré inequalities. • Weighted Korn inequalities. In some cases we exhibit counterexamples that show that the obtained weights are optimal. We also study these problems considering that the original space is a weighted Sobolev space W k,p ω (Ω).
SARS-CoV-2 Infection (COVID-19) and Rhinologic Manifestation: Narrative Review

Patients with severe pneumonia of unknown etiology presented in December 2019 in Wuhan, China. A novel coronavirus, severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), was isolated from the respiratory tracts of these patients. The World Health Organization (WHO) defined respiratory diseases due to SARS-CoV-2 infection as coronavirus disease 2019 (COVID-19). Many researchers have reported that the nasal cavity is an important initial route for SARS-CoV-2 infection and that the spike protein of this virus binds to angiotensin-converting enzyme 2 (ACE2) on epithelial cell surfaces. Therefore, COVID-19 is thought to significantly affect nasal symptoms and various rhinological diseases. In this review, we summarize the association between COVID-19 and various rhinological diseases, such as olfactory dysfunction, rhinosinusitis, and allergic rhinitis.
Deciphering Eurasian otter (Lutra lutra L.) and seal (Phoca vitulina L.; Halichoerus grypus F.) diet: Metabarcoding tailored for fresh and saltwater fish species

Long‐lived top predators shape biodiversity structure in their ecosystems and predator–prey interactions are critical in decoding how communities function. Studies on the foraging ecology of seals and Eurasian otters in Western Europe are outdated and most studies solely performed traditional hard part analysis. Molecular metabarcoding can be used as an innovative noninvasive diet analysis tool, which has proven efficient and complementary to hard part analysis, however, lacking application in the wider North Sea area. In this study, DNA from digesta, collected between 2014–2020, were used to identify fish species in the diet of 47 Eurasian otters, 54 harbour seals and 21 grey seals by applying a next‐generation metabarcoding approach. A newly designed 16S rRNA primer, providing the best coverage of >130 local marine and freshwater fish species, was used to amplify prey DNA from seal scats and otter gut content sampled from the North Sea and regional freshwater bodies. Frequent fish species included tench, ninespine stickleback and white bream in otters; hooknose and common roach in grey seals and Pleuronectidae and sand gobies in harbour seals. Bipartite network analysis showed a strong overlap of harbour and grey seal diets. Otter diet intersected with both seal species in terms of freshwater species. This study provides new knowledge about dietary composition and community assemblage of fish prey in otters and seals in the North Sea and regional freshwaters, and a new molecular tool to elucidate predator–prey interactions and interspecies competition in complex and changing ecosystems under pressure from anthropogenic activities.
Students' metacognition in solving non-routine problems

Students’ metacognition abilities based on their aspects have different levels. Metacognition aspects had categorized into parts of awareness aspects, evaluation aspects, and aspects of regulation. This study aims to describe how students are metacognitive in solving non-routine problems based on awareness, evaluation, and regulation characteristics. This research is a descriptive qualitative study with a sampled class VIII A Junior High School Batik Special Program (PK) Surakarta, which consisted of six students. The instruments in this research are non-routine problems or tests, observation sheets, and interview guidelines. The questions validator in this research are two teachers and a Mathematics Education lecturer from the University of Muhammadiyah Surakarta. The data collection technique uses tests, observations, and interviews. The data analysis technique of research had carried out through three stages: data reduction, data presentation, and conclusion drawing. This study concluded that the student's metacognition of eighth grade in solving non-routine problems had not developed better. Only one student can ideally find the metacognition aspects of awareness, evaluation, and regulation. Compared to medium-capable students, students with high abilities can discover the metacognition aspects well. In comparison, students with low skills have not been able to find all indicators of metacognition. Based on the results, further research may discover students’ obstacles in implementing metacognition for mathematical problem-solving.
Prospective Evaluation of Kidney Function in Long-Term Survivors of Pediatric CNS Tumors

Purpose: Numerous acute effects of chemotherapeutics on kidney function are well described. However, data on the long-term effects of chemotherapy in the growing population of childhood central nervous system (CNS) tumor survivors is limited. We aimed to evaluate the kidney function of a cohort of long-term CNS tumor survivors treated with different standard chemotherapeutic regimens. Methods: Patients treated for a CNS tumor were prospectively evaluated up to 12 years after completion of their therapy. Examination of kidney function was performed during routine follow-up visits. Blood pressure and blood and urine parameters were analyzed for kidney function evaluation. Glomerular function was assessed by calculating the estimated glomerular filtration rate (eGFR), tubular functions were analyzed by measuring serum electrolytes, bicarbonate and phosphate reabsorption, and proteinuria was assessed by calculating the protein/creatinine ratio and phosphate reabsorption. Results: None of the 65 patients evaluated suffered from clinically relevant kidney impairment (eGFR < 90 mL/min/L, 73 m2). There was no association between chemotherapy dose and eGFR. Only two patients showed mild signs of tubulopathy and 11 patients were diagnosed with elevated blood pressure. Conclusion: With adequate supportive measures, such as sufficient hydration according to chemotherapy protocol guidelines, as well as avoidance or close monitoring of additional nephrotoxic medication, impaired kidney function is rare in CNS tumor survivors treated with standard chemotherapy. Nonetheless, long-term follow-up is essential for early detection of mild impairment of kidney function.
Combined effects of quetiapine and opioids: A study of autopsy cases, drug users and sedation in rats

Fatal opioid poisonings often involve methadone or morphine. This study aimed to elucidate if quetiapine, a widely used sedative antipsychotic medication, may increase the risk of fatal opioid poisoning by additive inhibitory effects on the central nervous system. We used data from 323 cases of fatal methadone or/and morphine poisonings autopsied from 2013 to 2020, a survey of 34 drug users, and performed blinded placebo‐controlled studies in 75 Flinders Resistant Line rats receiving three cumulative intraperitoneal doses of vehicle, methadone (2.5, 10 and 15 mg/kg), morphine (3.75, 15 and 22.5 mg/kg), quetiapine (3, 10 and 30 mg/kg) or quetiapine combined with methadone or morphine. Quetiapine was detected in 20.4% of fatal opioid poisonings with a significantly increased frequency over time, primarily in low or therapeutic concentrations, and was not associated with methadone or morphine concentrations. Use of quetiapine, most commonly in low‐to‐moderate doses to obtain a sleep‐inducing or tranquillizing effect, was reported by 67.6% of survey respondents. In the animal studies, a significant impairment of sedation score, performance on the rotarod and open field mobility was observed in all treatment groups compared with vehicle. However, the effect of quetiapine plus the opioid was not significantly different from that of the opioid alone. Thus, no additive sedative effects were observed in rats. Our results suggest that quetiapine is more often an innocent bystander than a contributor to fatal opioid poisoning. However, the combined effects on other parameters, including blood pressure, cardiac rhythm and respiratory rate, need investigation.