Miracle-dz/UniFAR-FTUs huggingface dataset:
Association of Tdap vaccine guidelines with vaccine uptake during pregnancy

Objective In 2012, recommendations for universal tetanus toxoid, reduced diphtheria toxoid, and acellular pertussis (Tdap) vaccination during pregnancy were released. Our objective was to determine if Tdap, influenza, and pneumococcal vaccine uptake during pregnancy changed after the release of the guidelines, and identify factors associated with receiving the Tdap and influenza vaccine after 2012. Methods We conducted a retrospective cohort study on pregnant individuals who initiated prenatal care before 20 weeks’ gestation between 11/2011-11/2012 (“pre-guideline”) and 12/2012-12/2015 (“post-guideline”). Vaccine uptake dates were abstracted from medical records. The pre and post-guideline cohorts were compared to determine if Tdap vaccine uptake and timing improved after the new Tdap guidelines. We additionally examined influenza and pneumococcal vaccine uptake before and after guidelines. Factors associated with receipt of the Tdap and influenza vaccine during pregnancy in the post-guideline cohort were evaluated using multivariable logistic regression models. Results Of 2,294 eligible individuals, 1,610 (70.2%) received care in the post-guideline cohort. Among the pre-guideline cohort, 47.4% received Tdap, whereas Tdap uptake increased to 86.1% after the guidelines (p<0.001). Similarly, receiving the Tdap vaccine between the recommended time of 27–36 weeks gestational age improved from 52.5% to 91.8% after the guidelines (p<0.001). Vaccine frequency for influenza improved significantly from 61.2% to 72.0% (p<0.001), while frequency for pneumococcus were low and unchanged. An increased number of prenatal visits was associated with receiving the Tdap and influenza vaccines during pregnancy (respective, aOR 1.09 95% CI 1.05–1.13; aOR 1.50 95% CI 1.17–1.94). Non-Hispanic Black individuals were less likely to receive both the Tdap and influenza vaccines during pregnancy compared to non-Hispanic White individuals (respective, aOR 0.51 95% CI 0.33–0.80; aOR 0.68 95% CI 0.48–0.97). Conclusions Receipt and timing of Tdap vaccine improved after implementation of the 2012 ACIP guidelines. Receipt of influenza vaccine uptake also improved during the study period, while uptake of the pneumococcal vaccine remained low. Significant racial disparities exist in receipt of Tdap and influenza vaccine during pregnancy.
Action Costs Rapidly and Automatically Interfere with Reward-Based Decision-Making in a Reaching Task

Abstract It is widely assumed that we select actions we value the most. While the influence of rewards on decision-making has been extensively studied, evidence regarding the influence of motor costs is scarce. Specifically, how and when motor costs are integrated in the decision process is unclear. Twenty-two right-handed human participants performed a reward-based target selection task by reaching with their right arm toward one of two visual targets. Targets were positioned in different directions according to biomechanical preference, such that one target was systematically associated with a lower motor cost than the other. Only one of the two targets was rewarded, either in a congruent or incongruent manner with respect to the associated motor cost. A timed-response paradigm was used to manipulate participants’ reaction times (RT). Results showed that when the rewarded target carried the highest motor cost, movements produced at short RT (<350 ms) were deviated toward the other (i.e., non-rewarded, low-cost (LC) target). In this context participants needed an additional 150-ms delay to reach the same percentage of rewarded trials as when the LC target was rewarded. Crucially, motor costs affected the total earnings of participants. These results demonstrate a robust interference of motor costs in a simple reward-based decision-making task. They point to the rapid and automatic integration of motor costs at an early stage of processing, potentially through the direct modulation of competing action representations in parieto-frontal regions. The progressive overcoming of this bias with increasing RT is likely achieved through top-down signaling pertaining to expected rewards.
Autism Spectrum Disorder (ASD) and the Family Inclusive Airport Design Experience

The literature on air travellers with psychiatric disorders is limited. This perspective article highlights various travel-related aspects of autism spectrum disorder (ASD). The airport experience can be stressful for families of children with autism spectrum disorder (FwASDs). The aim of this study was to explore the airport experience of FwASDs using the value co-creation process approach to assist airport managers in designing improved experiences for this specific passenger segment. This study responds to the current climate in which airports are developing awareness programmes in relation to children who require special assistance at airports. The prevalence of children with ASD is 1/68. While a number of airports throughout the world have adopted procedures addressing the needs of those with cognitive impairment, these advances are far from universal. As part of an academic–industry collaboration between Vueling airlines and the Spanish airport operator Aena, 25 FwASDs took part in an inclusive airport research project in the city of Barcelona from November 2015 to April 2016. Employing a qualitative methodology that incorporated focus groups, ethnographic techniques, and post-experience surveys, the study contributes to extending the body of knowledge on the management of the value co-creation process for challenging passenger segments within the airport context. The study explains how ensuring adequate resource allocation to this passenger segment can improve the family-inclusive design of the airport experience and offers managerial recommendations.
The Determinants of Firm Growth in Small and Micro Firms - Evidence on Relationship Lending Effects

This paper examines the impact of firm level variables on the growth of small and micro firms operating in Finland. This study is the first one to investigate the impact that lending relationships have on growth. The results of our primary regressions show that close lending relationships enhance growth for all firms, but that only the larger firms in our sample benefit from more competitive banking markets. When we split the data into manufacturing and non-manufacturing firms, we find that only non-manufacturing firms benefit from close bank-borrower relationships. We additionally find that younger firms exhibit higher growth rates than older firms. Firm size seems to have a more complicated relationship with growth. Our results suggest that in the case of smaller firms an increase in size initially increases growth, but the effect is reversed after a certain level. For the larger firms with more than ten employees, we cannot reject Gibrat's law. Contrary to previous studies, we find that legal form is a significant determinant of firm growth only in the absence of more detailed ownership variables.
What the Doctor Would Prescribe: Physician Experiences of Providing Voluntary Assisted Dying in Australia

Background Like many countries where voluntary assisted dying (VAD) is legal, eligible doctors in Victoria, Australia, have sole legal authority to provide it. Doctors’ attitudes towards legalised VAD have direct bearing on their willingness to participate in VAD and consequently, on whether permissive laws can effectively facilitate access to VAD. The study aimed to explore how some Victorian doctors are perceiving and experiencing the provision of legalised VAD under a recently commenced law. Methods Semi-structured interviews with 25 Victorian doctors with no in-principle objection to legalised VAD were conducted between July 2019-February 2020. Interviews were recorded, transcribed, and analysed using thematic analysis. Ethical approval from the relevant institution was obtained. Results Doctors perceive or experience VAD to fundamentally challenge traditional medical practice. Barriers to access to VAD derive from applicant, communication, and doctor-related factors. Doctors’ willingness to participate in VAD is situation specific.
Attitudes Toward Lesbians, Gay Men, and Their Rights in a Sample of Ecuadorian Cisgender Men and Women

ABSTRACT Since 1997, Ecuador has undergone a series of changes to ensure family rights to sexual minorities. However, there is still limited research regarding attitudes toward them. This study focused on the attitudes toward lesbians (L), gay men (G), and their rights. A sample of 318 cisgender Ecuadorians who responded to an online survey was recruited. Analyses indicated that men, heterosexuals, who practice their religion, attend more frequently to religious services, and identify as conservative showed higher levels of prejudice against LG as well as less support toward their rights. Further, participants who did not have LG acquaintances, friends, family members, and those who did not know any LG parented family showed less support toward these populations. Multiple regression analyses indicated that believing that a person’s sexual orientation is learned significantly predicted the attitudes measured in our study. Implications of these findings to help reduce prejudice against LG individuals are discussed.
Musculoskeletal ultrasonography in rheumatic diseases

Ultrasonography is an imaging technique based on sound waves used for the evaluation of soft tissues. Sound waves have been used for a long time in nonmedical fields, including military defense systems, radar systems, and detection of icebergs. Technological advances resulted in new techniques becoming available for medical imaging, including ultrasonography, magnetic resonance imaging, and computed tomography. Nowadays, the use of imaging has become a gold standard protocol in the diagnosis of many diseases, and recently developed diagnosis and therapy options provide more efficient treatment of rheumatic diseases. Thus, it has become possible to prevent structural damage and disability in patients with rheumatic disease. Musculoskeletal ultrasonography is becoming a preferred imaging technique for rheumatic diseases, as it has many advantages. Among its advantages are being inexpensive, being radiation-free, having a dynamic image capacity, helping to detect disease activity, and helping with early detection and diagnosis of structural damage. This review summarizes the use of ultrasonography in rheumatic diseases.
Workaholism Prevention in Occupational Medicine: A Systematic Review

Introduction: Given the extent of workaholism identified in the literature, it seems essential to consider effective preventive measures. The purpose of this article is to summarize literature data on possible collective and individual preventive measures against workaholism, especially in occupational medicine. Method: We conducted a systematic literature review in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. Results: 155 articles were retrieved in March 2019, but only 15 well-designed studies providing concrete measures to prevent workaholism were included. The various measures were classified using the traditional distinction between three levels of prevention. At the first level of prevention, workaholism can be avoided by implementing a protective organizational culture. The second level of prevention rather focuses on individual training and counselling to address the negative consequences of workaholism. Finally, the third level of prevention combines cognitive and behavioral interventions that enable professional and social reintegration of workaholics. Discussion: This literature review confirms the multifactorial origin of workaholism and the involvement of organizational factors, supporting the necessary contribution of companies in its prevention. This review also reinforces the growing perception of workaholism as a behavioral addiction. Occupational physicians play a key role in this preventive approach as they can influence both working conditions and individual care. The highlighted preventive measures seem to be not only favorable to workaholics, but also to companies. Conclusion: This review provides field tools that can be used at the various levels of workaholism prevention. Nevertheless, intervention studies are required to confirm the effectiveness of the measures presented.
A Bayesian Federated Learning Framework With Online Laplace Approximation

Federated learning (FL) allows multiple clients to collaboratively learn a globally shared model through cycles of model aggregation and local model training, without the need to share data. Most existing FL methods train local models separately on different clients, and then simply average their parameters to obtain a centralized model on the server side. However, these approaches generally suffer from large aggregation errors and severe local forgetting, which are particularly bad in heterogeneous data settings. To tackle these issues, in this paper, we propose a novel FL framework that uses online Laplace approximation to approximate posteriors on both the client and server side. On the server side, a multivariate Gaussian product mechanism is employed to construct and maximize a global posterior, largely reducing the aggregation errors induced by large discrepancies between local models. On the client side, a prior loss that uses the global posterior probabilistic parameters delivered from the server is designed to guide the local training. Binding such learning constraints from other clients enables our method to mitigate local forgetting. Finally, we achieve state-of-the-art results on several benchmarks, clearly demonstrating the advantages of the proposed method.
Acoustic visualization of large scale macroplankton and micronekton distributions across the Norwegian shelf and slope of the Norwegian Sea.

We present results from acoustical (38 kHz split beam) surveys, biologieal sampling (trawling, zooplankton nets), and measurements of physical parameters (salinity, temperature, currents) aeross and along the shelf off Norway (62-700N). Major recurrent struetures were apparent both geographically and with time. Off the shelf, two deep seattering layers prevailed; one of 50-100 m thickness where the upper border by day fluetuated between 100 and 200 m depth, and one loeated deeper between 300-500 m. The upper layer was mainly composed of mesopelagie fish (Maurolicus muellerD and krill (Meganyctiphanes norvegica), while the lower layer eonsisted of krill (Meganyctiphanes norvegica), mesopelagie fish (Maurolicus muelleri, Benthosema glaciale), shrimps (Sergestes arcticus, Pasiphaea multidenta), and jellyfish (Periphylla periphylla). During winter, these two layers roughly eomprise 95 % of the baekseattering volume (biomass) in the upper 500 m. The shallow layer partly intrudes onto the eontinental shelf, where the bottom topography exerts strong impact on its distribution. In June/July an additional scattering layer was apparent in the upper 20-30 m throughout most of the study area, though integrated baekseattering biomass varied by a factor of 50. In the south the layer was associated with water masses of salinity <35 (Le. with coastal eharaeteristies). Further north the layer was found off the shelf in water with stronger oeeanie characteristics as wel1. Hydrographie features indicated that eoastal water and biomass was transported off the shelf in connection with gyres over the banks. Trawl eatches showed that this structure was composed of 0group herring, fish (mainly seith), and krill. Baekscattering volume was positively correlated with abundance of O-group herring caught in trawl, but was not eorrelated with the meso-zooplankton biomass (mainly Calanus finmarchicus), or other components of the trawl catches. The lack of positive correlations between acoustic backseattering volume, and biomass from net and trawl sampies probably reflected differences in seleetivity of the sampling methods.
The Moderating Role of Emotion Regulation in the Recall of Negative Autobiographical Memories

When facing a negative event, people implement different strategies to regulate ongoing emotions. Although the previous literature has suggested that the emotional intensity of a negative episode is associated with the characteristics of the subsequent autobiographical memory, it is still unknown whether emotion regulation (ER) moderates this relationship. In the present study, we provided undergraduate students with a smartphone-based diary to report a negative episode immediately after its occurrence and rate the momentary use of two ER strategies: cognitive reappraisal and rumination. To explore autobiographical memory, two “surprise” recall tasks were performed one week and one month after the event. According to the results, cognitive reappraisal was linked with better memory performances, and a tendency to retrospectively underestimate the negativity of highly intense events was observed only in participants adopting high rates of this strategy. Conversely, intense rumination was found to be associated with less detailed memories of emotionally intense events, as well as with higher emotional involvement with negative episodes over time, regardless of their intensity. Together, our results support the maladaptive role of rumination and the adaptive influence of cognitive reappraisal on autobiographical memory.
Interest on reserves, helicopter money and new monetary policy

We build a nonlinear dynamic model with currency, demand deposits and bank reserves. Monetary base is controlled by central bank, while money supply is determined by the interactions between central bank, commercial banks and public. In economic crises when banks cut loans, monetary policy following a Taylor rule is not efficient. Negative interest on reserves or forward guidance is effective, but deflation is still likely to be persistent. If central bank simultaneously targets both interest rate and money supply by a Taylor rule and a Friedman’s k-percent rule, inflation and output are stabilized. An interest rate rule policy is just a subset of a more general monetary policy framework in which central bank can move interest rate and money supply in every direction.
Knowledge, Attitudes and Practices toward Hepatitis B Virus Infection among Students of Medicine in Vietnam

Background: Building capacity in hepatitis B virus prevention and management for medical students and health professionals is one of the pillars of the national viral hepatitis control strategy. Methods: A cross-sectional study was conducted at eight medical universities from the northern, central and southern regions of the country between May and November 2020 using a systematic random sampling technique. Results: Among 2000 participants, 84.2% reported they had been tested for hepatitis B and 83.9% had received the hepatitis B vaccine. The mean knowledge, attitude, practice score was 40.2 out of 54 (74.4%) with only 19.9% of the study participants obtaining a good score. In multivariate analysis, fifth year students, students from central universities, students who had tested positive for hepatitis B and students who had received hepatitis B vaccine or had encountered patients with chronic hepatitis B had significantly higher knowledge score (p < 0.05). The study showed lack of trust in the hepatitis B vaccine safety and lack of confidence in providing counselling, testing and management of patients with chronic hepatitis B. Conclusion: Findings from our research emphasized an immediate need to improve the medical schools’ training curriculum in Vietnam to enable students’ readiness in hepatitis B prevention and management.
Inflammation Markers in Infants of Mothers with Gestational Diabetes

Abstract Aim Pentraxin-3, high sensitive CRP (HsCRP) and adropin were investigated in cord blood of infants of mothers with gestational diabetes mellitus (IDM) to evaluate the exposure of fetus to inflammation and whether there is any correlation with clinical findings. Methods Forty IDM and forty three infants whose mother did not have diabetes were included in this prospective study. Adropin, pentraxin-3 and HsCRP levels were measured in the cord blood samples. Echocardiographic measurements were performed in the first three days of life. Results Adropin and pentraxine-3 levels were significantly lower and HsCRP levels were significantly higher in IDM group. Echocardiographic measurements of myocardial hypertrophy were negatively correlated with adropin. Conclusion Alterations in these markers in IDM supports the hypothesis of in utero fetal exposure to inflammation caused by gestational diabetes mellitus. Potentially, cord blood adropin might be used as a predictor for complications of diabetes.
Effectiveness of an Academic-Practice Team Approach on Research Capacity Building of Nurses and Public Health Professionals

The purpose of this study was to determine the need for research training among nurses and health professionals in a rural province of Thailand and to evaluate the effectiveness of the interventions designed to address the identified factors. This two-phase study used a cross-sectional design with one-group pre- and post-tests. In phase I, 149 subjects from 16 subdistrict health promoting hospitals and one district hospital were sampled. As an intervention, an academic-practice team approach to research capacity building was designed. Twenty-four volunteers completed a three-time point assessment of intervention in phase II. Data were collected using self-report questionnaires and analyzed using bivariate and multivariate statistics. Phase-I results indicated that 33.6% of subjects were involved in the research implementation. They had a moderate perception of research barriers and capacity. The research experiences, capacity, and barriers associated with the research implementation were described in detail (p < 0.05). The only positive predictor of research implementation was research training (p < 0.001). The intervention improved 24 participants’ competency (p < 0.05). Most of their research proposals had received ethics approval and a small grant. These findings highlight the efforts of innovative research capacity development and its impact on research and health practices among nurses and health professionals.