Miracle-dz/UniFAR-FTUs huggingface dataset:
What are appropriate treatment goals for hypertension in patients over age 80

(55%) were enrolled with no specific indication for therapy. All patients in 47 trials and most patients in another 5 were receiving cyclosporine. The trials lasted for a median of 6 months (interquartile range, 3–12 months). Comparison arms included no treatment, placebo, and hypertensive medications by class. At 12 months, CCBs reduced graft loss compared with placebo or no treatment (17 trials, n=1,255; RR 0.75; 95% CI, 0.57–0.99), but did not reduce mortality (12 trials, n=792; RR 0.82; 95% CI, 0.37– 1.8). Dihydropyridine CCBs (mostly nifedipine, amlodipine, or felodipine) but not nondihydropyridine CCBs (diltiazem and verapamil) had improved diseaseoriented outcomes (serum creatinine and filtration rate), but with significant heterogeneity, which may have been due to pooling of different medications. At latest follow-up, there were nonsignificantly increased harms with angiotensin-converting enzyme inhibitors (lisinopril or enalapril) due to increased graft loss (1 trial, n=157; RR 7.4; 95% CI, 0.39–140) and death (2 trials, n=221; RR 4.0; 95% CI, 0.45–36) versus CCBs (amlodipine or nifedipine). There were no statistically significant results for comparisons using alpha-blockers, angiotensin receptor blockers, beta-blockers, or diuretics. Overall, the trials were of moderate quality and there was no evidence of publication bias. A 2014 meta-analysis of 5 RCTs (N=923) investigated the effects of calcineurin inhibitor selection on cardiovascular risk factors after renal transplant in adults. All of the patients were treated with an immunosuppressive regimen consisting of a calcineurin inhibitor (cyclosporine [n=602] or tacrolimus [n=321]), prednisolone, and either azathioprine or a mycophenolate derivative. Patients were excluded if they had diabetes prior to renal transplant, were treated with both calcineurin inhibitors sequentially, had toxicity from either, were less than 6 months posttransplant, or if they had experienced acute rejection or severe infection. Prior HTN was not an exclusion criterion. The risks of developing 4 disease-oriented outcomes were reported at 6 to 60 months: metabolic syndrome (using NCEP-ATPIII diagnostic criteria), hyperlipidemia, HTN, and diabetes mellitus. If the number of patients formally diagnosed with the outcome was not described, the number of patients on medications to treat the outcome was used instead. The only statistically significant difference was a lower risk of hyperlipidemia in patients treated with cyclosporine versus patients treated with tacrolimus (see TABLE). No difference was noted in the risk of metabolic syndrome. Although there were no other statistically significant differences, there was a higher incidence of HTN in cyclosporine-treated patients and a higher incidence of diabetes in tacrolimustreated patients. There was no statistically significant heterogeneity. Overall the trials were assessed to be of adequate quality with low risk of bias. No measure of publication bias was noted.
Intrinsic and extrinsic factors affecting consumer purchase intention for ready-to-eat food in Bangkok and its vicinity.

This research was aimed to study the intrinsic factors in term of convenience, health consciousness, product taste, product quality, and extrinsic factors in terms of price, product advertisement, product availability that led to purchase intention of readyto-eat (RTE) food of consumers in Bangkok and its vicinity. The closed-end questionnaires were applied to gather data from 250 consumers in Bangkok and its vicinity. The results indicated that the majority of respondents were 20-40 years old with equal percentage of male and female population. The research revealed that convenience was the most affecting intrinsic factor for the purchase intention of consumers, followed by the extrinsic factor in terms of product availability and product advertisement respectively. The remaining factors including price, product quality, health consciousness, and taste did not affect the purchase intention of consumers in Bangkok for RTE food.
Social Media and the Scourge of Visual Privacy

Online privacy has become immensely important with the growth of technology and the expansion of communication. Social Media Networks have risen to the forefront of current communication trends. With the current trends in social media, the question now becomes how can we actively protect ourselves on these platforms? Users of social media networks share billions of images a day. Whether intentional or unintentional, users tend to share private information within these images. In this study, we investigate (1) the users’ perspective of privacy, (2) pervasiveness of privacy leaks on Twitter, and (3) the threats and dangers on these platforms. In this study, we incorporate techniques such as text analysis, analysis of variance, and crowdsourcing to process the data received from these sources. Based on the results, the participants’ definitions of privacy showed overlap regardless of age or gender identity. After looking at the survey results, most female participants displayed a heightened fear of dangers on social media networks because of threats in the following areas: assets and identity. When the participants were asked to rank the threats on social media, they showed a high concern for burglary and kidnapping. We find that participants need more education about the threats of visual content and how these privacy leaks can lead to physical, mental, and emotional danger.
Design for the elderly: the acceptance of smart vests in the senior population

In the context of a fast-aging population, the health problem of the elderly has become a hot spot in the world [1]. In terms of long-term care, wearable health monitoring technology is an excellent way to address these issues [2]. As a kind of wearable system, the smart vest is used as the object of this study. In order to encourage the elderly to use and wear smart vests, this study investigated the factors affecting the acceptance of smart vests; moreover, it developed the technology acceptance model of smart vests for the elderly population. The model was certified with a sample of 152 older adults aged 60 and above. The results show that aesthetics as an external factor has a significant positive impact on perceived usefulness and ease of use. Perceived usefulness positively impacts the attitude of the elderly to use smart vests. This research provides valuable insights for future researchers and practitioners to improve the acceptance of smart vests among older adults.
A Preliminary Survey of Norovirus and Astrovirus Antigen in Diarrheic Stools of Children in Borno State, Nigeria

Background: Noroviruses and astroviruses are important agents of acute gastroenteritis among children. Acute gastroenteritis (AGE) is a major cause of morbidity and mortality in pediatric populations world-wide. Globally, an estimated 800 000 infants and young children die from diarrhea every year. Aims: This was a cross-sectional study that included acute diarrheic children presenting in Specialist Hospital, Nursing Home Health Centre and Ngamdu pediatric clinic in Borno state with the aim of detecting norovirus and astrovirus antigen. Two hundred children whose parent/ guardian consented were enrolled in the study. Methodology: Two hundred acute diarrheic and forty one nondiarrheic fecal samples were collected from children aged 5 or less between June 2013 – May 2014. Samples were screened for norovirus and astrovirus antigen using 3rd generation RIDASCREEN ELISA test kit. Demographic data of the children were obtained.
In Vitro Susceptibility Testing of Different Antimycotics and Disinfectants against Microsporum canis Isolated from Clinical Cases of Feline Dermatophytosis

Dermatophytosis is a common fungal condition of skin having zoonotic importance. Unconventional use of antimycotics and persistence in environment due to improper disinfection often leads to resistance and treatment failure. The purpose of this study was to observe in-vitro efficacy of different antimycotics and disinfectants against Microsporum canis. Skin scraping samples from affected cats were cultured and purified. Conidia were harvested from cultured colonies and count of 1.0 x 106/mL was adjusted by hemocytometer. Harvested conidial suspensions were inoculated on Mueller Hinton Agar (MHA) with antimycotic disks and incubated, then inhibition zone diameters were measured. Same conidial suspensions were inoculated with each disinfectant separately on Dermatophyte Test Medium (DTM) petri plates and colonies were enumerated after incubation. The data suggested that Itraconazole had maximum in-vitro effect followed by Miconazole, Clotrimazole and Ketoconazole, whereas Fluconazole demonstrated resistance. On the other hand, 5% phenol, 3% Hydrogen Peroxide, 1:10 sodium hypochlorite solutions were equally effective against M. canis spores.
ERS Task Force guideline for the diagnosis of primary ciliary dyskinesia

The diagnosis of primary ciliary dyskinesia is often confirmed with standard, albeit complex and expensive tests. In many cases, however, the diagnosis remains difficult despite the array of sophisticated diagnostic tests. There is no ‘gold standard’ reference test. Hence, a task force supported by the European Respiratory Society has developed this guideline to provide evidencebased recommendations on diagnostic testing, especially in the light of new developments in such tests, and the need for robust diagnoses of patients who might enter randomised controlled trials of treatments. The guideline is based on pre-defined questions relevant for clinical care, a systematic review of the literature, and assessment of the evidence using the GRADE (Grading of Recommendations, Assessment, Development and Evaluation) approach. It focuses on: clinical presentation, nasal nitric oxide, analysis of ciliary beat frequency and pattern by high-speed videomicroscopy analysis, transmission electron microscopy, genotyping and immunofluorescence. It then used a modified Delphi survey to develop an algorithm for the use of diagnostic tests to definitively confirm and exclude the diagnosis of PCD; also to provide advice when the diagnosis is not conclusive. Finally, this guideline proposes a set of quality criteria for future research on the validity of diagnostic methods for PCD.
Time‐Dependent Hydraulic Fracture Initiation

Rocks are known to fail in a time‐dependent manner similar to many brittle and quasi‐brittle materials. However, observed time dependence of hydraulic fracture initiation has ubiquitously been attributed to fluid flow‐related mechanisms without consideration of the intrinsic time dependence of rock failure. Laboratory delayed hydraulic fracturing breakdown experiments on three rocks (granite, sandstone, and limestone) show sensitivity to rock properties associated with subcritical crack growth as well as fluid viscosity and ambient confining pressure applied to the specimens. A new hydraulic fracture initiation model accounting for subcritical crack growth and fluid flow in a poroelastic medium, as well as the additional energy dissipation required for fluid flow in the rough fracture tip, is then used to estimate the value of the subcritical index n based on characterization experiments. Given this characterization data, the model is shown to be capable of predicting time‐dependent hydraulic fracture initiation with variation of fluid viscosity and confining stress.
Hemiarthroplasty vs. locking plate osteosynthesis – what is the better solution for displaced proximal humerus fractures?

Introduction: Displaced proximal humerus fractures pose significant clinical problems. The aim of this study was to compare treatment results between open reduction and internal fixation (ORIF) and hemiarthroplasty (HA). Material and methods: The study was a retrospective assessment. Sixtythree patients (30 HA, 33 ORIF) met the inclusion criteria; mean age: 64.5 years. The Constant-Murley scale, DASH score and VAS surveys for pain and satisfaction were used to evaluate the results. Results: The HA group: the constant score was 44 points, and the DASH score was 57 points; 53% of patients had osteolysis of the greater tubercle; none of the patients had revision surgery. ORIF group: the constant score was59 points, and the DASH score was 38 points; 21% of patients had a vascular necrosis; revision surgery was performed in 18% of cases. A significant correlation between good functional outcomes and young age of patients was found in the ORIF group (p-value < 0.048). Patients who started physical therapy earlier achieved better results. DASH scores were better compared to ones from the objective Constant-Murley score. There was no difference in satisfaction between HA and ORIF groups (p-value < 0.1). Conclusions: The ORIF should be considered for patients < 60 years old, but gives increased risk of urgent revision, due to screw protrusion. The HA provides fewer complications, lower risk of revision and can be better for patients between 60 and 70 years old. When choosing the treatment method, we should avoid focusing only on fracture configuration, but should also consider patient-related factors, such as age and lifestyle.
A novel experimental method of investigating anode-arc-root behaviors in a DC non-transferred arc plasma torch

A novel experimental method of investigating anode arc root was presented, and a plasma torch with multiple anodes was designed. With this apparatus, the number of anode arc roots, their position, and movement with changes in plasma current and gas-flow rate were studied. Results showed that multiple anode arc roots can coexist and their number was more related to plasma current than gas-flow rate. The number of anode arc roots increased with increased plasma current. The anode arc root can move forward and backward in the arc plasma jet, and its position was related to current and gas-flow rate. The anode arc root moved forward with increased current, whereas the anode arc root moved forward first and backward with increased gas-flow rate. Based on the finding, a new non-transferred arc model was established. Finally, the anode arc root motion was classified as steady, slight vibration, alternating motion, jumping motion, and multiple arc root modes. These results can serve as a reference for revealing the mechanism of plasma discharge, optimization design of arc plasma jet, and high-quality plasma generation.
Systematics of Vriesea (Bromeliaceae): phylogenetic relationships based on nuclear gene and partial plastome sequences

Vriesea is the second largest genus in Tillandsioideae, the most diverse subfamily of Bromeliaceae. Although recent studies focusing on Tillandsioideae have improved the systematics of Vriesea, no consensus has been reached regarding the circumscription of the genus. Here, we present a phylogenetic analysis of core Tillandsioideae using the nuclear gene phyC and plastid data obtained from genome skimming. We investigate evolutionary relationships at the intergeneric level in Vrieseeae and at the intrageneric level in Vriesea s.s. We sampled a comprehensive dataset, including 11 genera of Tillandsioideae and nearly 50% of all known Vriesea spp. Using a genome skimming approach, we obtained a 78 483-bp plastome alignment containing 35 complete and 55 partial protein-coding genes. Phylogenetic trees were reconstructed using maximum-likelihood based on three datasets: (1) the 78 483 bp plastome alignment; (2) the nuclear gene phyC and (3) a concatenated alignment of 18 subselected plastid genes + phyC. Additionally, a Bayesian inference was performed on the second and third datasets. These analyses revealed that Vriesea s.s. forms a well-supported clade encompassing most of the species of the genus. However, our results also identified several remaining issues in the systematics of Vriesea, including a few species nested in Tillandsia and Stigmatodon. Finally, we recognize some putative groups within Vriesea s.s. , which we discuss in the light of their morphological and ecological characteristics.
Understanding treatment disconnect and mortality trends in renal cell carcinoma using tumor registry data.

403 Background: Previous research has demonstrated a rise in overall and cancer specific mortality over time despite increased detection and treatment of kidney cancer, termed “treatment disconnect. ” Our aim was to assess the impact of missing data and rising incidence on mortality trends using national tumor registry data. Methods: Using Surveillance, Epidemiology, and End Results (SEER) data, we identified all patients with a kidney cancer diagnosis from 1973-2009. We estimated overall mortality rates by tumor size after accounting for lags from diagnosis to death and using multiple imputation for missing data. Mortality rates for all patients irrespective of tumor size were also estimated after adjustment for prior cumulative incidence using ridge regression. Results: 73,647 patients met inclusion criteria, of which 22.7% had missing tumor size data. Compared to observed rates, significant decreases in the change in mortality rate per 100,000 US population from 1983 to 2009 were noted for 2-4cm (Δobs1.
An exploratory factor analysis of HONOS-LD scales

Purpose The purpose of this study is to identify clinically meaningful groups of Health of the Nation Scales Learning Disabilities (HONOS-LD) single-item scales that might be used as short scales that are more reliable than single-item scale scores and more focused than the sum of scale scores. The single-item scales are likely to be unreliable in many applications. The sum of scale scores is a heterogeneous measure that is not a good representative of any specific difficulties that people who have intellectual disabilities may have and the effects of interventions on any specific difficulties may be masked by fluctuations in the ratings of other scales. Design/methodology/approach A total of 2,109 pseudonymised complete HONOS-LD ratings were factor-analysed using principal factor extraction and oblimin rotation. Three-, four- and five-factor rotated patterns were examined. Findings Three factors that each have three or more strong loadings (≥|0.50|) were identified that jointly included 11 single-item scales: one representing problems with cognitive competencies, one representing depressive phenomena or other mood problems and one representing problems with social competencies. A weaker factor that represents behaviour that challenges services is indicated; it includes five single-item scales. Both the cognitive competencies and social competencies groups of items were also reported in a previous study by Skelly and D’Antonio (2008) and may be stable. The present study’s factor representing behavioural difficulty has some similarity to Skelly and D’Antonio’s “functional behaviour and attachment disturbance” group. In other respects, the present study and the previous study differ. Research limitations/implications The outcomes of these factor analyses indicate that some of the single-item scales can be combined into groups. However, the specific groups found in this study must be regarded as possibly unstable because of the likelihood of weak inter-rater reliability in HONOS-LD data and differences between this analysis and Skelly and D’Antonio’s. Further research is needed to support or modify them. Practical implications The cognitive competence and social competence groups of items may be used as subscales if they are convenient. The groups representing mood and behavioural problems should be supported by further research before being used. Originality/value This is the second published factor analysis of the HONOS-LD and includes a much larger data set than the first. It has some similarities to and differences from the first and is a further step in the process of identifying useful groupings of HONOS-LD single-item scales.
Opioid agonist treatment in the Veterans Health Administration: is health care local?

Purpose Opioid use disorder (OUD) poses a national public health challenge including for the Veterans Health Administration (VHA). However, the responsiveness of VHA, as a centralized national health care system, to local conditions has not been studied. The purpose of this paper is to examine the correlation of measures of population-based OUD case identification and provision of opioid agonist treatment (OAT) in VHA and in local systems at the state level thus evaluating the responsiveness of VA as centralized health system to local conditions. Design/methodology/approach Correlation of VHA administrative data and local survey data reflecting OUD and OAT rates were evaluated with Pearson correlations. Further analyses examined the correlation of VHA and non-VHA OUD and OAT measures with state rates of opioid-related deaths, median income, health insurance coverage and education levels. Findings VHA rates of OUD and OAT at the state level were both significantly correlated with corresponding state data from the National Survey on Drug Use and Health (r=0.28, p=0.048 and r=0.71, p=0.002, respectively). Both OUD and OAT in VHA were positively and significantly correlated with state rates of opioid-related deaths, while indicators of OAT were significantly associated with higher state-level median income, health insurance coverage and levels of education. Practical implications Although centrally managed from Washington, D.C., VHA case identification and OAT service delivery appear to be correlated with relevant local measures. Social implications Significant associations with general population indicators point to underlying conditions that may shape both VHA and local health system performance. Originality/value Public health systems would benefit from performance evaluation data to examine responsiveness to local conditions.
MANAJEMEN KONFLIK KELUARGA POLIGAMI DAN MONOGAMI

Family conflict is a natural and common thing whether in polygamous or monogamous families. How to manage conflict can determine the impact of the conflict. The purpose of this study was tofind out the differences in conflict management between polygamous and monogamous families.This study used a quantitative approach with a non-probability sampling method using purposivesampling technique with 60 respondents (30 respondents from polygamous families and 30respondents from monogamous families). data was collected using conflict management scale, thatdeveloped by the researcher based on the theory of family conflict resolution. The result of ManWhitney Test showed that a significant value 0.358, which mean that there were no differencesbetween polygamous and monogamous families in managing conflict.