Miracle-dz/UniFAR-FTUs huggingface dataset:
How to be Gracious about Political Loss—The Importance of Good Loser Messages in Policy Controversies

Accepting defeat in political decision-making is crucial for the health of democracies. At the same time, being a good loser is challenging. How can citizens be motivated to be gracious about various types of political loss? In this paper, we study whether political leaders can play an important role in boosting the perceived quality of decision-making processes among losers in policy conflicts. We propose and test the impact of a simple intervention post-decision: good loser messages delivered by co-partisan leaders that remind citizens about the rules of the game. Three survey experiments on probability samples of the Norwegian and Swedish population (total n = 4700) show that good loser messages can indeed boost the process evaluations of policy losers. These findings emphasize the potential of procedural messaging to build loser’s consent between elections.
Renal stone prevalence and risk factors in Jeddah and Riyadh

Introduction: Nephrolithiasis is a common problem worldwide, especially in hot areas like Saudi Arabia. This retrospective study investigated the current prevalence and risk factors of renal stones in Jeddah and Riyadh, Saudi Arabia. Methods: A non-interventional cross-sectional study was conducted from November 2018 to June 2019 at King Abdulaziz University Hospital, Jeddah, Saudi Arabia. This study included 1031 participants (age ≥18 years) from Jeddah (n = 652, 63.30%) and Riyadh (n = 379, 36.80%). Of them, 169 (16.40%) had renal stones while 862 (83.60%) had no renal stones. All participants filled out a questionnaire distributed via social media, which contained questions regarding eating and drinking habits. Results: Significant differences were found between the groups regarding frequencies of intake of black tea and orange/lemon juice. The number of patients who consumed cow meat was significantly higher among those without renal stones than among those with renal stones. Significant high risk for renal stones was found in those who consumed energy drink >1 can/day, black tea >1 cup/day, and orange/lemon juice >1 glass/day. Conclusion: This study revealed that some eating habits play a major role in the development of urinary stones in the Saudi population. Therefore, a dietary intervention on a large scale and health, education in this regard may be helpful in preventing the 25 related to renal stone.
Junior high school students’ abilities in solving the open-ended mathematical problems with the context of Songket motif

Many researchers stated that most students struggle to solve higher mathematical problems, including open-ended problems. One of many solutions is to apply a realistic context close to students. Hence, this research aimed to analyze students’ abilities in solving an open-ended mathematical problem using the Songket context, particularly the Kembang Tengah motif. The subjects were 24 seventh graders. The instruments for this descriptive research were an open-ended problem and an interview sheet. The results show that in solving the open-ended problem, 88.33% of students understood the problem, 59.72% were able to construct, and 72.22% applied the plan, while 52.78% wrote the conclusion. No students evaluated their solution to the problem. In implementing open-ended problems in the traditional context, students have different solutions based on their various experiences with the context, problem-solving schema, and mean-putting on the problem. They also applied multiple problem-solving strategies in working the problem. The similarity was the use of assumptions in solving the problem. However, some assumptions were inconsistent, neither their prior work nor other mathematical concepts. Therefore, teachers and researchers need to emphasize students’ written self-evaluation to check and improve their solutions. Another suggestion is to see the metacognitive process in solving the open-ended mathematical problem using a specific tradition. Furthermore, teachers should engage more in using open-ended problems and scaffold students when facing obstacles in solving them.
Network Embeddedness and Innovation: Evidence From the Alternative Energy Field

Researchers have long studied the effect of network embeddedness on innovation outcomes, resulting in mixed findings. In this paper, we aim to take a novel approach to reconcile prior conflicting perspectives. We argue that previous seemingly discrepant findings may stem from ignoring different forms of network embeddedness and innovation. An innovator has doubly embedded relations in innovation networks: relational and structural embeddedness (SE). Additionally, innovations are categorized into two distinct types: exploratory and exploitative innovations. Our analysis is based on 2936 patent records involving 1561 inventors from a large U.S. company over a 16-year period. The findings indicate that, both relational and SE contribute to promoting exploitative innovation, while they have inverted U-shaped relationships with exploratory innovation. Furthermore, we argue that the whole network structure (e.g., the small-world quotient) must be considered to fully understand the effectiveness of network embeddedness. The implications of our findings are discussed for embeddedness, innovation, and network theory. For policy practice, researchers and knowledge workers should be more aware of modifying the levels of relational and SE, adopt appropriate embeddedness levels in a different situation, and match their embeddedness strategy with the whole structure of the intrafirm network.
Classification of divorce causes during the COVID-19 pandemic using convolutional neural networks

The COVID-19 pandemic has affected day-to-day activities. Some families experienced a positive impact, such as an increase of bonding between family members. However, there are families that experienced a negative effect, such as the emergence of various conflicts that lead to a divorce. Based on the literature, it can be stated that the COVID-19 pandemic contributed to the increasing number of divorce rates. This paper proposes a convolutional neural network (CNN) classification algorithm in determining the dominant causes of the increase in divorce rate during the COVID-19 pandemic. CNN is considered suitable for classifying large amounts of data. The data used as research materials are available on the official website of the Indonesian Supreme Court. This research utilizes Supreme Court divorce decisions from March 2020 to July 2021, which constitutes 15,997 datasets. The proposed number of layers implemented during the classification is four. The results indicate that the classification using CNN is able to provide an accuracy value of 96% at the 100th epoch. To provide a baseline comparison, the classical support vector machine (SVM) method was performed. The result confirms that CNN outweighs SVM. It is expected that the results will help any parties to provide a suitable anticipation based on the classified dominant causes of the divorce during the COVID-19 pandemic.
Effect of oxidation on the structural and functional properties of myofibrillar in Coregonus peled

The effects of the degree of oxidation (0.01 mmol/L FeCl3, 0.1 mmol/L ascorbic acid, 1 - 20 mmol/L H2O2) principally induced by Fenton systems on the structural and functional properties of Coregonus peled myofibrillar proteins (MP) was investigated. When the oxidation levels of MP increased, their carbonyl groups increased but sulfhydryl groups decreased (p < 0.05). SDS-PAGE analysis revealed more cross-linking and protein polymerisation in oxidised MP. FTIR properties suggested that oxidation increased conformational changes of MP. The functional results indicated that moderate oxidation (5 - 10 mmol/L H2O2) of MP improved their foaming capacity thus providing better functional properties; while excessive oxidation (≥ 15 mmol/L H2O2) led to the deterioration of their functional properties due to the formation of large aggregates, and therefore, should be avoided in their application in the food processing industry.
I CAN’T GET NO SATISFACTION: EXPLORING INDONESIAN GUESTS’ SATISFACTION AND SERVICE QUALITY IN SOUTH AFRICAN HOTELS

This study aims to determine whether the dimensions of service quality affect the satisfaction of Indonesian tourists who visit South Africa and use hotel services, as well as to analyse the most dominant factors in influencing Indonesian tourists' satisfaction toward hotels’ service in South Africa. The population in this study were Indonesian tourists who had just returned from South Africa and used hotel accommodations. Samples were obtained randomly at the Soekarno Hatta International Arrival Terminal, Tangerang, Indonesia in 2019 before the Covid-19 pandemic. The sample was taken around 100 respondents by using non-probability sampling approach with the accidental sampling method. It is discovered that Indonesian guests are pleased with the service quality of the hotels during their stay in South Africa and that the Indonesia guest’s revisit intention quite high. Also, it is suggested that the hotel managements in South Africa need to maintain the elements that have been rated satisfactory by Indonesian guests and need to improve the things that are still lacking. This study contributes an empirical basis in strategic aspect for managing foreign tourists/hotel guests’ satisfaction from abroad perspective.
Longitudinal Associations Between Household Solid Fuel Use and Handgrip Strength in Middle-Aged and Older Chinese Individuals: The China Health and Retirement Longitudinal Study

Background Household solid fuel have been associated with changes of handgrip strength (HGS). However, no study has explored the longitudinal associations between household solid fuel use and HGS. Thus, the aim of our cohort study was to investigate the longitudinal associations between household fuel use and HGS. Methods The study was based on the China Health and Retirement Longitudinal Study. A handheld dynamometer was used to measure HGS. Household fuel use statuses were collected using questionnaires. Analyses of covariance were performed to examine the associations between household fuel use and HGS. Results The study included 9,382 participants during a 4-year follow-up. The participants who used solid fuel for cooking had more decreases of HGS than those who used clean fuel (P < 0.0001). The least square means (95% CIs) of changes of HGS for participants who used solid fuel and those who used clean fuel for cooking were −1.67 (−2.15, −1.19) and−2.27 (−2.75, −1.79), respectively. The association between fuel use for heating and HGS was non-significant (P = 0.63). The interaction terms of sex to cooking fuel (P = 0.04) and smoking to cooking fuel (P < 0.001) were significant; men and participants who had ever smoked had higher decreases in HGS. Conclusion Using household solid fuel for cooking but not heating was associated with more decreases in HGS. Proper ventilation and clean fuel should be promoted for public health.
Frequency, Etiology, Mortality, Cost, and Prevention of Respiratory Tract Infections—Prospective, One Center Study

Background: Ventilator-associated pneumonia (VAP) is the most monitored form of respiratory tract infections (RTIs). A small number of epidemiological studies have monitored community-acquired pneumonia (CAP), non-ventilator hospital-acquired pneumonia (NV-HAP) and ventilator-associated tracheobronchitis (VAT) in intensive care units (ICUs). The objective of this study was to assess the frequency, etiology, mortality, and additional costs of RTIs. Methods: One-year prospective RTI surveillance at a 30-bed ICU. The study assessed the rates and microbiological profiles of CAP, VAP, NV-HAP, VAT, and VAP prevention factors, the impact of VAP and NV-HAP on the length of ICU stays, and the additional costs of RTI treatment and mortality. Results: Among 578 patients, RTIs were found in 30%. The CAP, NV-HAP, VAP, and VAT rates/100 admissions were 5.9, 9.0, 8.65, and 6.05, respectively. The VAP incidence density/1000 MV-days was 10.8. The most common pathogen of RTI was Acinetobacter baumannii MDR. ICU stays were extended by VAP and NV-HAP for 17.8 and 3.7 days, respectively, and these RTIs increased the cost of therapy by 13,029 and 2708 EUR per patient, respectively. The mortality rate was higher by 11.55% in patients with VAP than those without device-associated and healthcare-associated infections (p = 0.0861). Conclusions: RTIs are a serious epidemiological problem in patients who are admitted and treated in ICU, as they may affect one-third of patients. Hospital-acquired RTIs extend hospitalization time, increase the cost of treatment, and worsen outcomes.
Effects of spearmint (Mentha spicata L.) infusion in drinking water during rabbit fattening on the microbial and physicochemical qualities of the end meat product

The objective of the present work was to evaluate the effects of the administration of spearmint (Mentha spicata L.) infusion into drinking water (0, 5, and 10 g.L-1) in rabbits during 28 days of fattening on the microbiological and lipid stability of the end meat product, as well as the evaluation of meat and carcass quality. The rabbits were sacrificed, and the quality of the carcass and meat was evaluated. Once the meat was obtained, burger patties were made, which were then subjected to microbiological and physicochemical evaluation through the application of various treatments for 14 days. The results did not show an effect on the quality of the carcass; however, for the infusion treatment with 5 g of spearmint, the previous portion corresponding to the skeletal muscle, longissimus dorsi, was greater than the control treatment. Regarding the meat quality, the hardness parameter of the texture profile analysis was higher in the control and treatment with 5 g of spearmint. The microbiological analysis on day 0 showed that there was no growth of Staphylococcus in the treatments with spearmint infusion as compared to the control; the enterobacterial count at day 7 was higher in the control group than in the treatments with spearmint infusion; and on day 14, the total viable count was higher in control than in the treatments with spearmint infusion. In the physicochemical analysis, only the colour (L*, a*, and b*) showed significant differences in the parameters at 0 and 14 days for the control. In conclusion, the spearmint infusion in drinking water for fattening rabbits could influence the physicochemical and microbiological characteristics of the end meat product, and could be considered as an alternative for improving the lipid and microbiological stability of rabbit meat products.
Early-Life Exposure to Non-Absorbable Broad-Spectrum Antibiotics Affects the Dopamine Mesocorticolimbic Pathway of Adult Rats in a Sex-Dependent Manner

Gut microbiota with a stable, rich, and diverse composition is associated with adequate postnatal brain development. Colonization of the infant’s gut begins at birth when parturition exposes the newborn to a set of maternal bacteria, increasing richness and diversity until one to two first years of age when a microbiota composition is stable until old age. Conversely, alterations in gut microbiota by diet, stress, infection, and antibiotic exposure have been associated with several pathologies, including metabolic and neuropsychiatric diseases such as obesity, anxiety, depression, and drug addiction, among others. However, the consequences of early-life exposure to antibiotics (ELEA) on the dopamine (DA) mesocorticolimbic circuit are poorly studied. In this context, we administered oral non-absorbable broad-spectrum antibiotics to pregnant Sprague-Dawley dams during the perinatal period (from embryonic day 18 until postnatal day 7) and investigated their adult offspring (postnatal day 60) to assess methylphenidate-induced conditioned place preference (CPP) and locomotor activity, DA release, DA and 3,4-dihydroxyphenylacetic acid (DOPAC) content in ventral tegmental area (VTA), and expression of key proteins within the mesocorticolimbic system. Our results show that ELEA affect the rats conduct by increasing drug-seeking behavior and locomotor activity induced by methylphenidate of males and females, respectively, while reducing dopamine striatal release and VTA content of DOPAC in females. In addition, antibiotics increased protein levels of DA type 1 receptor in prefrontal cortex and VTA of female rats, and tyrosine hydroxylase in VTA of adult male and female rats. Altogether, these results suggest that ELEA alters the development of the microbiota-gut-brain axis affecting the reward system and the response to abuse drugs in adulthood.
Naïve Primary Mouse CD8+ T Cells Retain In Vivo Immune Responsiveness After Electroporation-Based CRISPR/Cas9 Genetic Engineering

CRISPR/Cas9 technology has revolutionized genetic engineering of primary cells. Although its use is gaining momentum in studies on CD8+ T cell biology, it remains elusive to what extent CRISPR/Cas9 affects in vivo function of CD8+ T cells. Here, we optimized nucleofection-based CRISPR/Cas9 genetic engineering of naïve and in vitro-activated primary mouse CD8+ T cells and tested their in vivo immune responses. Nucleofection of naïve CD8+ T cells preserved their in vivo antiviral immune responsiveness to an extent that is indistinguishable from non-nucleofected cells, whereas nucleofection of in vitro-activated CD8+ T cells led to slightly impaired expansion/survival at early time point after adoptive transfer and more pronounced contraction. Of note, different target proteins displayed distinct decay rates after gene editing. This is in stark contrast to a comparable period of time required to complete gene inactivation. Thus, for optimal experimental design, it is crucial to determine the kinetics of the loss of target gene product to adapt incubation period after gene editing. In sum, nucleofection-based CRISPR/Cas9 genome editing achieves efficient and rapid generation of mutant CD8+ T cells without imposing detrimental constraints on their in vivo functions.
On the LED Illumination and Communication Design Space for Visible Light Communication

Visible light communication (VLC) is a promising application for short-range wireless digital communications, presenting itself as a breakthrough for future lighting systems. The use of light emitting diodes (LEDs) as transmitters by modulating their light intensity requires the correct design from both illumination and communication perspectives. However, in face of worldwide efforts for efficient energy consumption, the modulation of light imposes an energy cost that VLC cannot avoid. It has been shown that the modulation of light intensity brings unavoidable extra power expense. Thus, this paper brings a deeper analysis of the LED concerning its operating limits and efficacy with joint illumination and VLC intended modulations. The study uses a static photometrical, electrical, and thermal model of the LEDs, in order to perform an analytical analysis regarding illumination and communication. Base modulation strategies supported by the IEEE 802.15. 7 standard (PHY I and PHY II) were compared side-by-side with other classical modulation schemes, such as pulse amplitude modulation, phase shift keying, frequency shift keying, quadrature amplitude modulation, and orthogonal frequency division multiplexing, from an energy conversion point of view. The results mark the design space connecting a set of possible modulation schemes with the desired average total light flux. This analysis guides the selection of the modulation technique according to the available power for a VLC system when efficacy is constrained. Moreover, the results show that the thermal effects not only reduce LED efficacy, but also constrict possible operating conditions regarding VLC in terms of communication signal power.
Effectivity of (Personalized) Cognitive Behavioral Therapy for Insomnia in Mental Health Populations and the Elderly: An Overview

Insomnia is very prevalent in psychiatry and is considered a transdiagnostic symptom of mental disorders. Yet, it is not only a consequence of a mental condition but may also exert detrimental effects on psychiatric symptom severity and therapeutic response; thus, adequate insomnia treatment is particularly important in psychiatric populations. The first choice of intervention is cognitive behavioral therapy for insomnia (CBT-I) as it is rather effective, also in the long run without side effects. It is offered in various forms, ranging from in-person therapy to internet-delivered applications. CBT-I protocols are typically developed for individuals with insomnia disorder without co-occurring conditions. For an optimal therapeutic outcome of CBT-I in individuals with comorbid mental disorders, adaptations of the protocol to tailor the treatment might be beneficial. Based on a literature search using major search engines (Embase; Medline; APA Psych Info; and Cochrane Reviews), this paper provides an overview of the effectiveness of the different CBT-I applications in individuals with diverse comorbid mental conditions and older adults and describes the functionality of CBT-I protocols that have been personalized to specific psychiatric populations, such as depression, substance abuse, and schizophrenia spectrum disorder. Finally, we discuss urgent needs for insomnia therapy targeted to improve both sleep and psychopathologies.
Determinants and Consequences of Renal Function Variations With Aldosterone Blocker Therapy in Heart Failure Patients After Myocardial Infarction: Insights From the Eplerenone Post–Acute Myocardial Infarction Heart Failure Efficacy and Survival Study

Background— We evaluated the effect of the selective mineralocorticoid receptor antagonist eplerenone on renal function and the interaction between changes in renal function and subsequent cardiovascular outcomes in patients with heart failure and left ventricular systolic dysfunction after an acute myocardial infarction in the Eplerenone Post–Acute Myocardial Infarction Heart Failure Efficacy and Survival Study (EPHESUS). Methods and Results— Serial changes in estimated glomerular filtration rate (eGFR) were available in 5792 patients during a 24-month follow-up. Patients assigned to eplerenone had a decline in eGFR with an adjusted mean difference of −1.4±0.3 mL · min−1 · 1.73 m−2 compared with placebo (P<0.0001), an effect that appeared within the first month (−1.3±0.4 mL · min−1 · 1.73 m−2) and persisted throughout the study. Overall, 914 patients experienced a decline in eGFR >20% in the first month, 16.9% and 14.7% in the eplerenone and placebo groups, respectively (odds ratio, 1.15; 95% confidence interval, 1.02–1.30; P=0.017). In multivariate analyses, determinants of this early decline in eGFR were female sex, age ≥65 years, smoking, left ventricular ejection fraction <35%, and use of eplerenone and loop diuretic. An early decline in eGFR by >20% was associated with worse cardiovascular outcomes independently of baseline eGFR and of the use of eplerenone, which retained its prognostic benefits even under these circumstances. Conclusions— In patients with heart failure after acute myocardial infarction and receiving standard medical care, an early decline in eGFR is not uncommon and is associated with poor long-term outcome. Eplerenone induced a moderately more frequent early decline in eGFR, which did not affect its clinical benefit on cardiovascular outcomes.