Miracle-dz/UniFAR-FTUs huggingface dataset:
The Use of Teleconsultations by Nurses in Primary Care in Minas Gerais, Brazil: the Experience of the Telehealth Network of Minas Gerais

Primary care is the doorway into the Brazilian public health system. On that level of care, nurses have a main role. As such, they can benefit from telehealth initiatives that bring them closer to specialists of other levels of care. This study aims to evaluate the use, by nurses, of a large scale Brazilian teleconsultation service. Methods: Teleconsultations requested by nurses from April 2007 to February 2014 were analysed to identify: the time of the day they were sent; the specialties they were directed to; and the main socioeconomic features of the cities from which they originated. In addition, a sample of teleconsultations from January to February 2014 was examined for the most common types of queries. Results: A total of 30,258 teleconsultations were analysed. They were mainly directed to medical subspecialties (76.5%). Nursing categories received 20.7% of the queries. Of all teleconsultations, 66.5% were performed during the working hours of the Primary Care units (8 am to 5 pm Monday to Friday). Most of the 632 cities that sent queries during this period had worse socioeconomic indices than the state’s average. Concerning teleconsultations performed from January to February 2014, most queries were about aetiology (29.0%) and pharmacological treatment (18.5%). Conclusion: This study from a large scale Brazilian teleconsultation service showed that nurses direct their requests mostly to medical subspecialties. The cities from where most teleconsultations were originated are notably more underserved. The main queries were about aetiology and pharmacological treatment.
Gender Gap in Entrepreneurship

Using data on the entire population of businesses registered in the states of California and Massachusetts between 1995 and 2011, we decompose the well-established gender gap in entrepreneurship. We show that female-led ventures are 63 percentage points less likely than male-led ventures to obtain external funding (i.e., venture capital). The most significant portion of the gap (65 percent) stems from gender differences in initial startup orientation, with women being less likely to found ventures that signal growth potential to external investors. However, the residual gap is as much as 35 percent and much of this disparity likely reflects investors’ gendered preferences. Consistent with theories of statistical discrimination, the residual gap diminishes significantly when stronger signals of growth are available to investors for comparable female- and male-led ventures or when focal investors appear to be more sophisticated. Finally, conditional on the reception of external funds (i.e., venture capital), women and men are equally likely to achieve exit outcomes, through IPOs or acquisitions.
Phagocytic glioblastoma-associated microglia and macrophages populate invading pseudopalisades

Abstract Hypoxic pseudopalisades are a pathological hallmark of human glioblastoma, which is linked to tumour malignancy and aggressiveness. Yet, their function and role in the tumour development have scarcely been explored. It is thought that pseudopalisades are formed by malignant cells escaping from the hypoxic environment, although evidence of the immune component of pseudopalisades has been elusive. In the present work, we analyse the immunological constituent of hypoxic pseudopalisades using high-resolution three-dimensional confocal imaging in tissue blocks from excised tumours of glioblastoma patients and mimic the hypoxic gradient in microfluidic platforms in vitro to understand the cellular motility. We visualize that glioblastoma-associated microglia and macrophages abundantly populate pseudopalisades, displaying an elongated kinetic morphology across the pseudopalisades, and are oriented towards the necrotic focus. In vitro experiments demonstrate that under hypoxic gradient, microglia show a particular motile behaviour characterized by the increase of cellular persistence in contrast with glioma cells. Importantly, we show that glioblastoma-associated microglia and macrophages utilize fibres of glioma cells as a haptotactic cue to navigate along the anisotropic structure of the pseudopalisades and display a high phagocytic activity at the necrotic border of the pseudopalisades. In this study, we demonstrate that glioblastoma-associated microglia and macrophages are the main immune cells of pseudopalisades in glioblastoma, travelling to necrotic areas to clear the resulting components of the prothrombotic milieu, suggesting that the scavenging features of glioblastoma-associated microglia and macrophages at the pseudopalisades serve as an essential counterpart for glioma cell invasion.
Do Strong Winds Impact Water Mass, Nutrient, and Phytoplankton Distributions in the Ice‐Free Canada Basin in the Fall?

In general, strong wind events can enhance ocean turbulent mixing, followed by episodic nutrient supply to the euphotic zone and phytoplankton blooms. However, it is unclear whether such responses to strong winds occur in the ice‐free Canada Basin, where the seasonal pycnocline is strong and the nutricline is deep. In the present study, we monitored a fixed‐point observation (FPO) station in the Canada Basin for about 3 weeks in the fall of 2014 to examine the oceanic and biological responses to strong winds. At the FPO site, oceanic microstructure measurements, hydrographic surveys, and water sampling were performed with high temporal resolution, recording internal wave propagation, eddy passage, and water mass changes. Strong winds and internal wave propagation significantly enhanced the mixing above and at the seasonal pycnocline, but their effects were diminished at the nutricline, which was much deeper than the seasonal pycnocline. Therefore, wind‐induced mixing did not increase the upward nutrient supply from the nutricline and did not impact phytoplankton (chlorophyll a) distribution in the surface layer of the FPO site. The temporal evolution of the chlorophyll a concentration was most closely related to water mass changes. We also observed prominent subsurface chlorophyll a maxima with abundant large‐sized phytoplankton that were likely carried by warm‐core eddies to the FPO site. Phytoplankton biomass may have been sustained by the high concentration of ammonium within the eddy and ammonium regeneration at the seasonal pycnocline, where particulate organic matter likely accumulated. Plain Language Summary The Arctic basins, once covered with multiyear ice, are gaining ice‐free areas in summer and fall as an effect of global warming. An ice‐free upper ocean is more susceptible to wind forcing than ice‐covered waters. Here, we studied the oceanic and biological responses to strong winds in the ice‐free Canada Basin, where a density gap (pycnocline) was seasonally formed at a depth of about 20 m between the sea surface layer containing sea ice meltwater and the layer below. Although significant wind‐induced mixing was observed above and at this seasonal pycnocline, mixing was attenuated at nutricline depths (~60 m), where nutrient concentrations increased strongly with depth. Thus, nutrients were not supplied from the nutricline to the sea surface layer through wind‐induced mixing, and phytoplankton biomass did not increase in response to strong winds. However, phytoplankton biomass sometimes increased around the seasonal pycnocline, where ammonium was available for use in photosynthesis. This ammonium was likely supplied by warm‐core eddies transporting shelf water into the Canada Basin. Another conceivable source of ammonium was particulate organic matter suspended at the seasonal pycnocline that decomposed, producing ammonium.
Ecobehavioral Assessment of Paraeducator Behaviors That Support Engagement of Students With Disabilities

Due to a shortage of special education teachers and an increase in the number of students with disabilities, the use of paraeducators is common. Paraeducators frequently provide instruction, under the direction of a teacher, to support elementary students with disabilities in elementary school classrooms. However, if and how paraeducators implement foundational instructional strategies is largely unknown (e.g., opportunities to respond [OTR], praise). Likewise, how students with disabilities respond to paraeducators’ instructional behaviors is also unknown. With decades of evidence indicating that contextual factors (e.g., group size, activity type) influence interactions between educators and students, we relied on ecobehavioral assessment to measure paraeducators’ use of core instructional strategies and students’ response in the natural context. Our results indicated a correlation between higher rates of paraeducator-delivered OTRs and praise statements and increased student engagement. Of concern, paraeducators infrequently used core, evidence-based instructional approaches, and students often were not engaged. Findings suggest increased student engagement may depend on professional development efforts aimed at improving paraeducators’ implementation of these essential core strategies.
AKTIVITAS HIPOKOLESTEROLIMIK EKSTRAK ROSELA (Hibiscus sabdariffa) PADA TIKUS PUTIH DIABETES

Rosela is one of medicinal herbs. The aim of the study was to find out the hypocholesterolimic effect of oral intake of Rosela extract on diabetic white rat. This research applied Complete Randomized Design of four groups with five replications to each. The treatment for those groups was: no treatment, metformin 9 mg/200 g body weight, 250 mg/kg body weight of Rosela extract, and 500 mg/kg body weight of Rosela extract. The parameters used were cholesterol concentration before and after the treatment. The result showed that the extract of Rosela reduced cholesterol concentration.
Parametric studies on dry sliding wear behaviour of Al-7075 alloy matrix composite using S/N ratio and ANOVA analysis

Al7075/10 wt% TiO2 alloy composite has been fabricated by the stir casting method to investigate the influence of wear parameters. The microstructure of the produced composite was analyzed by scanning electronic microscopy. A pin-on-disc rig was used to carry out the wear test on produced composite under dry sliding conditions. The three wear control parameters such as load, sliding velocity and sliding distance were chosen to study the effects on the wear rate and coefficient of friction of composite. The experiments were planned as per L9 orthogonal array based on Taguchi’s design of experiments. The signal-to-noise ratio and analysis of variance techniques were employed to determine the optimum combination of parameters and the significant contribution of each parameter on the responses. The results exposed that the load was the most predominant factor affecting the wear rate and coefficient of friction followed by the sliding distance and sliding velocity. Finally, the regression equations were developed to predict the responses. The worn surface morphology of composite noticed that TiO2 reinforcement protects the matrix alloy from removal of material at all conditions. This investigation revealed that the wear resistance of the Al7075 alloy can be enhanced by the incorporation of TiO2 particles.
Dynamic Analysis of Multi Storey Building with Plan Irregularity and Vertical Irregularity under Different Bracings Systems

The rapid growth in population in urban area has given rise to the increase in construction of multi storey buildings in urban area to reduce the pressure of accommodation. In recent time designing aesthetically beautiful and complex buildings which has irregularities in plan, vertical irregularity, mass irregularity etc are done. But for high rise multi storey building the wind loads and seismic loads play dominant role. Buildings with irregularities suffer more damage than regular buildings when subjected to wind and seismic loads. Bracings, shear wall are some of the structural elements which can resist lateral loads. Bracings are highly effective and economical method of resisting seismic and wind loads. The objective of this study is to study the behaviour of building with bracings and without bracings under different seismic and wind zones using ETABS 2016 software. In this project the bracings selected are X bracings, v bracings, inverted v bracings. The bracings which gives better lateral resistance is found after analysis. In this project seismic analysis is done in two methods Response Spectrum analysis and Time History analysis and the deviation in results between the two methods are investigated.
Influence Work Station Design and Firm Constitutional Complaint Against Musculoskeletal on Stone Crusher Worker Progo in Magelang

A rock-breaking work that engaged in the informal sector and contain a great job risk to health and safety of workers. Solving Stone in the river Progo an informal jobs into one livelihood. In working stone crushers appears work attitude accordance with his needs. Work attitude or ergonomic working conditions caused by the design of work stations that were not appropriate in turn can lead to complaints such as disorders of the musculoskeletal system. This research is quantitative, using observational design "observational". These samples included 33 respondents. The sampling technique used in this research is purposive sampling.The instrument uses anthropometer set, the meter rolls, verbal nomeric scale questionnaires, observation sheets body constitution, Checklist health conditions, stationery, and cameras. , Data collection techniques throughmusculoskeletal complaints data collection before and after work design in the form of appropriate ergonomic chair that has been adapted to the body anthropometric and body constitution by means of direct observation and interviews in the study. Statistical analysis using one-way ANOVA test (one-way ANOVA). The research found p = 0.000, where the value (p <0.05), there is the effect of changes in the work station of the musculoskeletal complaints (skeletal muscle) workers Progo river stone crushers in Magelang, because there is the average difference between the value before work by after work and test results revealed very significant. Z value in the Wilcoxon test was -4.808. Price is negative (-) indicates complaint skeletal muscles before work is smaller than complaints skeletal muscles after work.
The Impact of Nocturia on Mortality: A Systematic Review and Meta-Analysis.

PURPOSE Nocturia (waking from sleep at night to void) is a common cause of sleep disruption and associated with increased comorbidity and impaired quality of life. However, its impact on mortality remains unclear. We performed a systematic review and meta-analysis to evaluate the association of nocturia with mortality, both as a prognostic and causal risk factor. MATERIALS AND METHODS We searched PubMed, Scopus, CINAHL and major conference abstracts up to December 31, 2018. Random effects meta-analyses addressed adjusted relative risks (RR) of mortality for people with nocturia and a meta-regression explored potential determinants of heterogeneity, including risk of bias. We applied the GRADE framework to rate the quality of evidence for nocturia as a prognostic risk factor for mortality and, separately, as a cause of mortality. RESULTS Of 5230 identified reports, 11 observational studies proved eligible. For the assessment of nocturia, ten studies used symptom questionnaires and one frequency-volume charts. Nocturia was defined as ≥2 episodes/night in six (55%), and as ≥3 episodes/night in five (45%) studies. Pooled estimates demonstrated a risk ratio of 1.27 (95% confidence interval 1.16-1.40; I2=48%; absolute 5-year mortality difference 1.6% and 4.0% in people aged 60 and 75 years, respectively). The pooled estimates of relative risk did not differ significantly across varying age, gender, follow-up time, nocturia case definition, risk of bias, or study region. We rated the quality of evidence for nocturia as a prognostic factor as moderate and as a cause of mortality as very low. CONCLUSIONS Nocturia is probably associated with an approximately 1.3-fold increased risk of death.
Supervisors' Knowledge and Use of Clinical Supervision to Promote Teacher Performance in basic schools

The study was designed to find out the knowledge of supervisors in clinical supervision and how they use it to promote teacher performance in basic schools. The study further aimed at determining the professional relationship between supervisors and teachers. The design was descriptive survey and data was collected using quantitative and qualitative methods. One hundred and eleven (111) participants were sampled comprising 83 teachers, 22 head teachers, five circuit supervisors, and one district head of supervision. A five-point likert scale questionnaire was used to collect the quantitative data while focus group discussion was used to collect the qualitative data. Descriptive statistics and chi square analysis were used to analyse the quantitative data while a content analysis was used to analyse the qualitative data. Findings from the quantitative data indicated that most basic school supervisors are knowledgeable in clinical supervision and use it in basic school supervision. On the contrary, evidence from the interview showed that they are unable to apply such knowledge adequately and effectively as required in supervising teachers. In addition, the result showed that supervisors do have cordial professional relationship with teachers. However, the results from the interview revealed that teachers think that most of them have the same qualifications and expertise as their supervisors so such teachers are not comfortable with the supervision from the supervisors. Based on the findings and discussions the study recommended that basic school supervisors must be trained in the use of clinical supervision and shed off some of their classroom and administrative responsibilities in order to use clinical supervision effectively to help improve teacher performance.
Extended-State-Observer-Based Event-Triggered Orbit-Attitude Tracking for Low-Thrust Spacecraft

This article addresses the coupled orbit-attitude tracking problem using low-thrust propulsion while aiming to minimize on-board spacecraft system communication. An adaptive controller is proposed by employing an event-triggered control and an extended-state-observer, where a simple strategy to tune the observer parameters is provided. Moreover, the event-triggering strategy updates and allocates the control signal to the thrusters at prescribed discrete events and is shown to significantly reduce the data-rate requirement. Finally, the performance of the controller is illustrated through numerical examples.
Efficient Detection and Classification of Epigenomic Changes Under Multiple Conditions

Epigenomics, the study of the human genome and its interactions with proteins and other cellular elements, has become of significant interest in recent years. Such interactions have been shown to regulate essential cellular functions and are associated with multiple complex diseases. Therefore, understanding how these interactions may change across conditions is central in biomedical research. Chromatin immunoprecipitation followed by massively-parallel sequencing (ChIP-seq) is one of several techniques to detect local changes in epigenomic activity (peaks). However, existing methods for differential peak calling are not optimized for the diversity in ChIP-seq signal profiles, are limited to the analysis of two conditions, or cannot classify specific patterns of differential change when multiple patterns exist. To address these limitations, we present a flexible and efficient method for the detection of differential epigenomic activity across multiple conditions. We utilize data from the ENCODE Consortium and show that the presented method, mixNBHMM, exhibits superior performance to current tools and it is among the fastest algorithms available, while allowing the classification of combinatorial patterns of differential epigenomic activity and the characterization of chromatin regulatory states.
Preparation of Nano Films from ZnO/MWCNT and Study their Applications as a Gas Sensor

: Thin nanoparticles of zinc oxide were prepared using sol-gel. “The samples were prepared nano thin film (71 nm), various weight ratios were added from the MWCNT to the colloidal solution and at a rate of” “(0.423, 0.921, 1.624%). These solutions were deposited by using the spin coating technique on the glass substrate and interdigitated finger electrode. For the purpose of knowing the sensitivity and the extent of response of these samples to detect the different vapors of some toxic gases (ethanol, methanol, acetone and nitrogen). Nano thin film were prepared by using spin coting technique. The synthetic properties of these membranes were studied using X-ray diffraction.
Catalanidad in the Kitchen: Tourism, Gastronomy and Identity in Modern and Contemporary Barcelona

Abstract Catalonia has, from the nineteenth century to the present day, promoted a distinct culinary tourism. Travel and tourism practices have, as early as the eighteenth century, worked as powerful agents of Spanish nation-building and self-identification. In the case of Catalonia, and Barcelona in particular, gastronomic promotion via touristic forums became a key outlet for the expression of such nationalist sentiment. Tracing the process from the earliest mass-tourism guide-books to Barcelona, passing through the regressive understanding of culinary and broader cultural difference during the Franco dictatorship, this essay recognizes the firm linking of food and Catalan identity. By the 1960s we can identify the reassertion of a Catalan gastronomic identity in the proliferation of gastronomic guides to the region and culinary tourism enterprises such as the recent ‘Ruta 1714’ campaign. Along the way, this essay examines the role of the Generalitat, the Catalan language, the mining of local history and various touristic entities and gastronomic figures in cementing the identification between Catalonia and gastronomy that has ultimately helped strengthen the region’s broader political and cultural recognition abroad.
How to Prevent Players from Teaming Up in Free-for-all Games: The Importance of Initial Contact

It has often been reported that gamers temporarily team up with their enemies in games that prohibit teaming in pursuit of accomplishing the final objective of the game. This behavior, referred to as “teaming”, is frequently observed in free-for-all games and spoils the enjoyment of other players. The current study analyzed data from an iterated economic game with a payoff structure and player constraints similar to those of free-for-all games. Results indicated that cooperative behaviors equivalent to teaming behavior emerged when cooperative intent between participants was successfully signaled and attended in the early stages of the game. Suggestions are made based on these findings which aim to prevent teaming behavior observed in free-for-all games.