Miracle-dz/UniFAR-FTUs huggingface dataset:
The relationship of coping skills with psychache in patients with depressive disorder

Suicide is a leading cause of death and disability worldwide. Psychache (psychological pain) and diminished tolerance of psychaches are important risk factors for suicide. People experiencing psychaches of similar severity may not demonstrate the same levels of tolerance because of various coping skills. This study aimed to determine the relationship between psychache, tolerance for psychache, and coping skills in individuals with depression and healthy controls. We included 73 patients with depressive disorders without comorbid mental disorders and 65 healthy controls. We applied beck depression inventory, beck hopelessness scale, beck suicidal ideation scale, psychache scale, tolerance for mental pain scale (TMPS), and coping attitudes evaluation scale (COPE) to all participants. People with depression had significantly higher COPE dysfunction scores than those in the control group did. Patients who had previously attempted suicide attempt(s) previously had significantly higher beck hopelessness scale, beck depression inventory, COPE dysfunction, and psychache scale scores, and lower TMPS-10 scores than those who did not attempt suicide. Mediation analyses revealed that dysfunctional coping skills played a partial mediating role in the relationship between psychache and the TMPS. The study revealed that dysfunctional coping skills were related to suicidal ideation and previous suicide attempts. These findings suggest that improving coping skills could help reduce the severity of suicidal ideation.
VDR gene ApaI polymorphism and risk of postmenopausal osteoporosis: a meta-analysis from 22 studies

Abstract Objective The ApaI polymorphism (G > T, rs7975232) of the vitamin D receptor (VDR) gene in the risk of postmenopausal osteoporosis has been widely researched, and the results have yielded conflicts. Therefore, we performed an updated pooled analysis to comprehensively assess the association between VDR ApaI polymorphism and postmenopausal osteoporosis risk. Methods We searched eligible studies about ApaI polymorphism and osteoporosis through the PubMed, Embase, CNKI and Wanfang databases; case–control studies containing available genotype frequencies of A/a were chosen. We used the odds ratio with 95% confidence interval to assess the strength of this association. Sensitivity analysis and publication bias assessment were performed. Trial sequential analysis (TSA) was performed to evaluate a sufficient sample. Results Twenty-two studies assessed the relationship between ApaI polymorphism and the risk of osteoporosis in postmenopausal women. The comprehensive analyses showed no significant association for ApaI polymorphism with postmenopausal osteoporosis in the overall population, equally valid for Asian and Caucasian subgroups with any genetic model. TSA still indicated the results were robust. Conclusion The present meta-analysis suggests that the VDR ApaI genotype may not affect the risk of postmenopausal osteoporosis in Asians and Caucasians.
Resolving the Delusion Paradox

Abstract Background and Hypothesis The neurocomputational framework of predictive processing (PP) provides a promising approach to explaining delusions, a key symptom of psychotic disorders. According to PP, the brain makes inferences about the world by weighing prior beliefs against the available sensory data. Mismatches between prior beliefs and sensory data result in prediction errors that may update the brain’s model of the world. Psychosis has been associated with reduced weighting of priors relative to the sensory data. However, delusional beliefs are highly resistant to change, suggesting increased rather than decreased weighting of priors. We propose that this “delusion paradox” can be resolved within a hierarchical PP model: Reduced weighting of prior beliefs at low hierarchical levels may be compensated by an increased influence of higher-order beliefs represented at high hierarchical levels, including delusional beliefs. This may sculpt perceptual processing into conformity with delusions and foster their resistance to contradictory evidence. Study Design We review several lines of experimental evidence on low- and high-level processes, and their neurocognitive underpinnings in delusion-related phenotypes and link them to predicted processing. Study Results The reviewed evidence supports the notion of decreased weighting of low-level priors and increased weighting of high-level priors, in both delusional and delusion-prone individuals. Moreover, we highlight the role of prefrontal cortex as a neural basis for the increased weighting of high-level prior beliefs and discuss possible clinical implications of the proposed hierarchical predictive-processing model. Conclusions Our review suggests the delusion paradox can be resolved within a hierarchical PP model.
Exoskeleton-Assisted Sit-to-Stand Training Improves Lower-Limb Function Through Modifications of Muscle Synergies in Subacute Stroke Survivors

Abnormal muscle synergies during sit-to-stand (STS) transitions have been observed post-stroke, which are associated with deteriorated lower-limb function and mobility. Although exoskeletons have been used in restoring lower-limb function, their effects on muscle synergies and lower-limb motor recovery remain unclear. Here, we characterized normal muscle synergy patterns during STS activity in ten healthy adults as a reference, comparing with pathological muscle synergy patterns in ten participants with subacute stroke. Moreover, we assessed the effects of a 3-week exoskeleton-assisted STS training intervention on muscle synergies and clinical scores in seven stroke survivors. We also investigated correlations between neuromuscular complexity of muscle synergies and clinical scores. Our results showed that the STS task involved three motor modules representing distinct biomechanical functions among healthy subjects. In contrast, stroke participants showed 3 abnormal modules for the paretic leg and 2 modules for the non-paretic leg. After the intervention, muscle synergies partially shifted towards the normal pattern observed in healthy subjects on the paretic side. On the non-paretic side, the synergy modules increased to three and neuromuscular coordination improved. Furthermore, the significant intervention-induced increases in Fugl-Meyer Assessment of Lower Extremity and Berg Balance Scale scores were associated with improved muscle synergies on the non-paretic side. These results indicate that the paretic side demonstrates abnormal changes in muscle synergies post-stroke, while the non-paretic side can synergistically adapt to post-stroke biomechanical deviations. Our data show that exoskeleton-based training improved lower-limb function post-stroke by inducing modifications in muscle synergies.
Country and community vs poverty and conflict: Teasing apart the key demographic and psychosocial resilience and risk factors for Indigenous clinic-referred children and adolescents

Objective: Indigenous young people are known to have adverse demographic and psychosocial factors affecting worse mental health outcomes and some household factors aiding resilience. In Australia, there has been no exploration of these factors in clinically referred Indigenous young people assessed in a culturally appropriate way. Methods: A total of 113 Indigenous children and adolescents, 217 non-Indigenous young people, age, gender, mental disorder symptom severity, symptom-linked distress and impairment matched, and 112 typically developing participants, age- and gender-matched were recruited. Cultural validity and reliability of the impairing symptoms in Indigenous young people were determined. Key demographic and psychosocial factors were compared across the three groups. Results: The Indigenous clinical group differed significantly from the other two groups that did not differ on three possibly protective measures examined. Key demographic and psychosocial risk factors in the Indigenous group differed significantly from the non-Indigenous clinical group which in turn differed from the typically developing participants. The three groups exhibited a progressively increased magnitude of difference. Conclusions: It remains imperative to nurture features that provide protection and enhance resilience for Indigenous young people and their communities. Indigenous status is linked to significant demographic and psychosocial disadvantage over and above that conferred by clinical impairment and its management. It is crucial that these features are managed and/or advocated for with those demographic and psychosocial factors of the greatest magnitude dealt with first. Future systematic investigations of the contribution of these key factors to mental health referral pathways, assessment and management are needed.
Decay of correlations, quantitative recurrence and logarithm law for Rovella attractors

In this paper we prove that a class of skew products maps with non uniformly hyperbolic base has exponential decay of correlations. We apply this to obtain a logarithm law for the hitting time associated to a contracting Lorenz (or Rovella) attractor at all the points having a well defined local dimension, and a quantitative recurrence estimation.
The practices of intravenous sodium bicarbonate therapy in neonatal intensive care units: A multi-country survey

A common occurrence in the neonatal intensive care unit (NICU) is metabolic acidosis. Sodium bicarbonate (SB) has been widely used, but there is insufficient evidence on how SB affects neonates in NICUs with metabolic acidosis. The worsening of intracellular acidosis, the impairment of myocardial function, fluctuations in cerebral blood flow, and intracranial hemorrhage are some of the unfavorable effects of SB treatment in neonates that have been documented in the literature. This study aimed to explore neonatologists’ practices for using intravenous SB (ISB) in NICUs. A multi-country survey was carried out in 2022 using an online questionnaire sent to neonatologists in various countries in order to gather information about the use of ISB in NICUs. A previously validated questionnaire was adapted and used in this study. The response rate was 67%. The findings show that 91.2% of neonatologists were using SB to correct metabolic acidosis in the NICU; 71.4% did not have written guidelines for using sodium bicarbonate. The majority of them (78.9%) reported that dosage is included in their guidelines for the use of ISB. The findings of this study emphasize the critical importance of providing guidelines in using ISB for managing metabolic acidosis in NICU to standardize procedures and reduce the use of potentially unsuitable and unsafe treatments, as it has been shown that 71.4% of neonatologists worldwide use sodium bicarbonate without guidelines.
A Novel Weber Local Binary Descriptor for Fingerprint Liveness Detection

In recent years, fingerprint authentication systems have been extensively deployed in various applications, including attendance systems, authentications on smartphones, mobile payment authorizations, as well as various safety certifications. However, similar to the other biometric identification technologies, fingerprint recognition is vulnerable to artificial replicas made from cheap materials, such as silicon, gelatin, etc. Thus, it is especially necessary to distinguish whether a given fingerprint is a live or a spoof one prior to such authentication. In order to solve the problems above, a novel local descriptor named Weber local binary descriptor for fingerprint liveness detection (FLD) has been proposed in this paper. The method consists of two components: the local binary differential excitation component that extracts intensity-variance features and the local binary gradient orientation component that extracts orientation features. The co-occurrence probability of the two components is calculated to construct a discriminative feature vector, which is fed into support vector machine (SVM) classifiers. The effectiveness of the proposed method is intuitively analyzed on the image samples and numerically demonstrated by Mahalanobis distance. Experiments are performed on two public databases from FLD competitions from 2011 and 2013. The results have proved that the proposed method obtains the best detection accuracy among the existing image local descriptors in FLD.
Computational-Based Aerodynamic Design for a Formula SAE Vehicle

The computational analysis and design of an aerodynamics system for a Formula SAE vehicle is presented. The work utilizes a stochastic-approximation optimization (SAO) process coupled with a computational fluid dynamics (CFD) solver. The methodology is presented in a general manner, and is applicable to other complex parametrizable systems. A mix of discrete and continuous variables is established to define the airfoil profile, location, sizing and angle of all wing elements. Objectives are established to maximize downforce, minimize drag and maintain a target vehicle aerodynamic balance. A combination of successive 2D and 3D CFD evaluations have achieved vehicle aerodynamic performance targets at a minimal computational cost.
IPDA filters in the sense of Gaussian mixture PHD algorithm

The Integrated Probabilistic Data Association (IPDA) type filters provide estimates of the underlying target probability of existence as well as they track state maintenance. For each scan, IPDA recursive calculates the probability of target existence in order to resolve the uncertainty. Likewise, Random Finite Set (RFS) is a method for single target and multi-target tracking. It provides a Bayesian recursion of multi-target distribution through the Finite Set calculus. Practical implementation of multi-target posterior recursion is too difficult. It was analytically proved that IPDA algorithm can be derived from the RFS based filter recursion under the linear Gaussian assumptions. Probability hypothesis density (PHD) filter is an alternative to this problem where only the first order moment of the complete multi-target posterior is propagated in time. In this article, IPDA and Gausian Mixtures PHD (GM PHD) filters in a single target tracking scenario are derived and compared. Simulations have demonstrated the superiority of IPDA filters in heavy clutters.
Novel compounds ZK-PI-5 and ZK-PI-9 regulate the reproduction of Spodoptera frugiperda (Lepidoptera: Noctuidae), with insecticide potential

Trehalase inhibitors prevent trehalase from breaking down trehalose to provide energy. Chitinase inhibitors inhibit chitinase activity affecting insect growth and development. This is an important tool for the investigation of regulation of trehalose metabolism and chitin metabolism in insect reproduction. There are few studies on trehalase or chitinase inhibitors' regulation of insect reproduction. In this study, ZK-PI-5 and ZK-PI-9 were shown to have a significant inhibitory effect on the trehalase, and ZK-PI-9 significantly inhibited chitinase activity in female pupae. We investigated the reproduction regulation of Spodoptera frugiperda using these new inhibitors and evaluated their potential as new insecticides. Compounds ZK-PI-5 and ZK-PI-9 were injected into the female pupae, and the control group was injected with solvent (2% DMSO). The results showed that the emergence failure rate for pupae treated with inhibitors increased dramatically and aberrant phenotypes such as difficulty in wings spreading occurred. The oviposition period and longevity of female adults in the treated group were significantly shorter than those in the control group, and the ovaries developed more slowly and shrank earlier. The egg hatching rate was significantly reduced by treatment with the inhibitor. These results showed that the two new compounds had a significant impact on the physiological indicators related to reproduction of S. frugiperda, and have pest control potential. This study investigated the effect of trehalase and chitin inhibitors on insect reproduction and should promote the development of green and efficient insecticides. Graphical Abstract
Phase transition in bilayer MoS2 under tensile loading: a molecular dynamics study

Molybdenum disulfide (MoS2), especially single-layer MoS2, has been experimentally and computationally discovered to exist in several different polymorphs exhibiting various electronic and mechanical properties. The morphology of MoS2 can be tuned through strain engineering. Molecular dynamics simulations are conducted to systematically study the phase transition of single-layer MoS2 and bilayer MoS2 under the uniaxial tensile condition at room temperature. The roles of edge and S-line vacancy are investigated. Phase transitions are always triggered near the edge and vacancy sites. The initiation of the metastable T″ phase can release the tensile stress in the lattice, followed by I4/mmm phase initiation, regardless of the edge conditions. The growth of the I4/mmm phase can cause the local buckling of the MoS2 plane. With a tilted S-line vacancy, I4/mmm phase is first initiated to reduce the local shear stress accumulated near the vacancy line. Overall, the phase transition mechanism of single layer and bilayer MoS2 under the uniaxial tensile loading is provided, which guides the future strain engineering of MoS2 in nanoelectronics applications.
A Strong Convergence Theorem for an Iterative Method for Finding Zeros of Maximal Monotone Maps with Applications to Convex Minimization and Variational Inequality Problems

Abstract Let E be a uniformly convex and uniformly smooth real Banach space, and let E* be its dual. Let A : E → 2E* be a bounded maximal monotone map. Assume that A−1(0) ≠ Ø. A new iterative sequence is constructed which converges strongly to an element of A−1(0). The theorem proved complements results obtained on strong convergence of the proximal point algorithm for approximating an element of A−1(0) (assuming existence) and also resolves an important open question. Furthermore, this result is applied to convex optimization problems and to variational inequality problems. These results are achieved by combining a theorem of Reich on the strong convergence of the resolvent of maximal monotone mappings in a uniformly smooth real Banach space and new geometric properties of uniformly convex and uniformly smooth real Banach spaces introduced by Alber, with a technique of proof which is also of independent interest.
Application of orthodontics combined with porcelain laminate veneers in the aesthetic restoration and flora regulation of anterior teeth

To evaluate the effectiveness of orthodontics in combination with porcelain laminate veneers (PLV) in the aesthetic restoration and flora regulation of anterior teeth. A retrospective analysis of 336 patients who underwent aesthetic restoration of anterior teeth in our hospital from April 2019 to September 2022 was performed and divided into a control group (n = 168) and an observation group (n = 168) according to the restorative modality. The restorative modality in the control group was conventional restorative remediation, while the restorative modality in the observation group was orthodontic combined with PLV treatment. To evaluate the excellent rate of aesthetic restoration of anterior teeth in the 2 groups, and compare the color, shape, degree of translucency, edge aesthetic score, complications and satisfaction rate of restoration of anterior teeth in the 2 groups before and after restoration. The observation group had a significantly higher rate of excellent aesthetic restorations (95.23%) compared to the control group (80.95%) (P < .001). The scores of anterior tooth color, morphology, degree of translucency and marginal aesthetics were improved in both groups after restoration compared to before restoration, and the scores were significantly higher in the observation group (P < .05). After restoration, the subgingival Digestive streptococcus, Campylobacter and Propionibacterium increased in both groups, but the number of bacterial strains was significantly less in the observation group (P < .05). Compared with the total complication rate in the control group (16.66%), the total complication rate in the observation group (2.38%) was significantly lower (P < .001). Compared with the control group (85.71%), the observation group had a significantly higher restoration satisfaction rate of 97.61%, with a statistically significant difference (P < .001). The application of orthodontics combined with PLV in the aesthetic restoration of anterior teeth has a significant clinical effect, which is conducive to improving the aesthetic restoration and satisfaction rate of anterior teeth, reducing the subgingival microbial imbalance and decreasing the incidence of complications.
Radio galaxies at low frequencies : high spatial and spectral resolution studies with LOFAR

This thesis uses novel observations from the Low Frequency Array to address open questions on the topic of galaxy evolution. The highest resolution images at ultra low radio frequencies are used to investigate the physical processes present in the radio emission from distant galaxies. Detections of spectral features from carbon atoms in a nearby galaxy are also presented and used to constrain the temperature and density of cold gas that is a key component of all galaxies.
Polyarteritis nodosa initially presenting as concomitant peripheral neuropathy and myositis in unilateral limb: A case report

Rationale: We report the case of a patient who initially presented with peripheral neuropathy and myositis without typical organ involvement, such as the kidneys, skin, or gastrointestinal system, but was ultimately diagnosed with polyarteritis nodosa (PAN). Patient concerns: A 62-year-old man presented with radicular pain in his right lower extremity. One week later, he complained of right ankle motor weakness and pain in the right posterior thigh, which led to admission. After 6 weeks of hospitalization, he newly experienced pain in his right testicle and anterior thigh. Diagnosis: The patient was initially diagnosed with polymyositis combined with sciatic neuropathy using magnetic resonance imaging, electrodiagnostic tests, and muscle biopsy. However, with the emergence of other systemic symptoms such as testicular pain, vasculitis was suspected, and the patient was reclassified as PAN using the 2007 European Medicines Agency algorithm and the American College of Rheumatology criteria. Interventions: The patient was treated with glucocorticoids for more than 6 months, and antiviral medication was prescribed to prevent hepatitis B virus reactivation. Outcomes: The patient’s radicular pain and pain in the right anterior and posterior thighs and testicle improved, and there were no signs of recurrence. Lessons: In patients presenting with radicular and focal muscle pain, it is crucial to consider the potential for PAN, as observed in this case report.
Functional Distributional Semantics at Scale

Functional Distributional Semantics is a linguistically motivated framework for modelling lexical and sentence-level semantics with truth-conditional functions using distributional information. Previous implementations of the framework focus on subjectverbobject (SVO) triples only, which largely limits the contextual information available for training and thus the capability of the learnt model. In this paper, we discuss the challenges of extending the previous architectures to training on arbitrary sentences. We address the challenges by proposing a more expressive lexical model that works over a continuous semantic space. This improves the flexibility and computational efficiency of the model, as well as its compatibility with present-day machine-learning frameworks. Our proposal allows the model to be applied to a wider range of semantic tasks, and improved performances are demonstrated from experimental results.