Miracle-dz/UniFAR-FTUs huggingface dataset:
Modelling of the Genre Short Story for Teaching Purposes: An Approach from a Systemic Functional Perspective

This article is framed in a research project called “Literature from a linguistic perspective: modelling and teaching of literary narrative genres and response genres” carried out within the framework of Systemic Functional Linguistics (SFL). One of the aims of this project is to create a model of the generic macro-structure of the literary macro-genre short story to be used for teaching purposes. This model is developed on the basis of the existent categories of personal narratives (Plum 2004; Martin and Rose 2008; Salmaso 2014, 2017, 2021) and fairy tales (Hasan 1997) in SFL. This article presents the results of a qualitative analysis of the generic macro-structure of six short stories. It provides a generic macro-structure potential for literary macro-genre short story, the elementary genres that are inserted in the constituents of this macro-genre and the reasons why such genres are inserted where they are. This article also presents a series of activities based on the generic macro-structure potential of short stories proposed, which provide a more objective tool for the analysis and comprehension of certain aspects of this macro-genre, like its organisation into different constituents, their purpose and their contribution to the overall purpose of the macro-genre, showing that systematic analysis of this genre can foster students' reading comprehension. This paper is expected to make, on the one hand, a theoretical contribution to SFL through an initial modelling of the macro-genre short story and, on the other hand, a practical contribution to the teaching of English through literature. Facultad de Filosofía y Letras, UNCuyo; Mendoza, Argentina. In these subjects, literary narrative texts are used as an essential teaching tool to foster students’ development of different linguistic competences. These texts
Using “Home” to Explain the Factors Affecting Residential Satisfaction The Case of Panama’s Heterogeneous Environments During The Covid-19 Crisis

ABSTRACT This study’s goal is to explore the representations of home that underlie residential satisfaction during the Covid-19 crisis, by developing new tools for housing research. We hypothesize that the concept of home helps explain the different experiences of social groups during the confinement period, and its effect on residential satisfaction. To test our hypothesis, we developed a mixed-methods approach departing from 135 original surveys. First a quantitative index was created, measuring four groups of home dimensions; the inside of home (1), the outside connection (2), home as protection against stressors (3) and home as a place for positive adaptation (4). Secondly, we used content analysis to enlarge the explanatory power of the index. Our results show the index is a viable tool for exploring the different experiences of confinement. Our method potentially improves research on residential satisfaction leading to more resilience, and better design guidelines for professionals.
A sandwich panel that autonomously repairs sudden large holes and defects for tankers and pipelines carrying hazardous matter

The self-healing of micro and macro cracks is vital for eliminating defects such as damage progression and loss of strength in structures. In this study, a polyurethane (PU) based geometrically self-healing sandwich structure was developed. The geometric healing agent, PU resin and activator, were filled into macrocapsules, and these capsules were filled into the Aluminum (Al) honeycomb cells. Self-healing of structural strength, large holes and cracks in developed sandwich structures were investigated by performing quasi-static compression and impact penetration tests. The sandwich structure with a self-healing capsules-filled core was damaged by subjecting it to quasi-static and penetration impact loads, and the healing agents in the broken capsules were mixed. The damage in the specimen was removed by geometric self-healing. Liquid and air permeability tests were applied to the PU foam used as a healing agent. No liquid permeability was observed in the structure. In addition, significant reductions in air permeability were obtained. Scanning electron microscope images were used to explore the characterization of the PU foam structure cells.
Synthesis of Novel Conjugated Linoleic Acid (CLA)-Coated Superparamagnetic Iron Oxide Nanoparticles (SPIONs) for the Delivery of Paclitaxel with Enhanced In Vitro Anti-Proliferative Activity on A549 Lung Cancer Cells

The application of Superparamagnetic Iron Oxide Nanoparticles (SPIONs) as a nanomedicine for Non-Small Cell Lung Carcinoma (NSCLC) can provide effective delivery of anticancer drugs with minimal side-effects. SPIONs have the flexibility to be modified to achieve enhanced oading of hydrophobic anticancer drugs such as paclitaxel (PTX). The purpose of this study was to synthesize novel trans-10, cis-12 conjugated linoleic acid (CLA)-coated SPIONs loaded with PTX to enhance the anti-proliferative activity of PTX. CLA-coated PTX-SPIONs with a particle size and zeta potential of 96.5 ± 0.6 nm and −27.3 ± 1.9 mV, respectively, were synthesized. The superparamagnetism of the CLA-coated PTX-SPIONs was confirmed, with saturation magnetization of 60 emu/g and 29 Oe coercivity. CLA-coated PTX-SPIONs had a drug loading efficiency of 98.5% and demonstrated sustained site-specific in vitro release of PTX over 24 h (i.e., 94% at pH 6.8 mimicking the tumor microenvironment). Enhanced anti-proliferative activity was also observed with the CLA-coated PTX-SPIONs against a lung adenocarcinoma (A549) cell line after 72 h, with a recorded cell viability of 17.1%. The CLA-coated PTX-SPIONs demonstrated enhanced suppression of A549 cell proliferation compared to pristine PTX, thus suggesting potential application of the nanomedicine as an effective site-specific delivery system for enhanced therapeutic activity in NSCLC therapy.
Encephalitis Associated With COVID-19 in A 7-year-old Boy: A Case Report

Coronaviruses (CoVs) are single-stranded RNA viruses described for >50 years. Novel coronavirus (SARS-Coronavirus-2: SARS-CoV-2) emerged in Wuhan and has spread globally. Coronavirus Disease 2019 (COVID-19) symptoms are primarily pulmonary (fever, dry cough, fatigue, pneumonia); however, other organs can be affected, including the gastrointestinal tract, kidneys, liver, heart, and brain. Pediatric COVID-19 is milder than the adult’s type. Children with severe disease often have an underlying co-morbidity, such as chronic lung disease or immunosuppression. SARS-CoV-1, MERS-CoV, HCoV-OC43, and HCoV-229E are associated with neurological complications. Neurological manifestations of COVID-19 are not well understood in adults or children, and these manifestations are not rare. The number of patients with neurological manifestations has been increasing Recently, especially in the third peak of the disease. Early diagnosis and timely management may lead to a better outcome. There are limited reports of neurological complications in the pediatric population. Further studies are required for early diagnosis and better results. We reported the third case of encephalitis in children without any respiratory or gastrointestinal manifestation. A 7-year-old male was admitted with fever and loss of consciousness. He presented no respiratory or gastrointestinal symptoms. He reported no medical history and history of substance abuse. Laboratory findings confirm that neurological manifestations might be expected in covid-19 infections, despite the absence of respiratory symptoms. The patient was treated, and the level of consciousness was gradually improving. Supportive treatment and outpatient follow-up were recommended.
The ethnopragmatics of English stage-of-life words as forms of address

ABSTRACT This paper examines the nominal category of stage-of-life words used in English address practices and presents an analysis of their interactional uses and meanings made adopting the principles and methods of ethnopragmatics. The paper has a twofold aim: (i) to highlight the polysemous nature of English stage-of-life words and make a clear distinction between their reference and address meanings; and (ii) to show that the address meanings of stage-of-life words reflect their sociopragmatic function in discourse. Using Natural Semantic Metalanguage (NSM) methodology, separate semantic explications are produced for the meanings expressed by each address noun in different interactional contexts. More generally, the present study highlights the interface between semantics, pragmatics and cultural assumptions, showing how this connection can be used as the starting point to conduct a proper ethnography of speaking.
Histidine methyltransferase SETD3 methylates structurally diverse histidine mimics in actin

Actin histidine Nτ‐methylation by histidine methyltransferase SETD3 plays an important role in human biology and diseases. Here, we report integrated synthetic, biocatalytic, biostructural, and computational analyses on human SETD3‐catalyzed methylation of actin peptides possessing histidine and its structurally and chemically diverse mimics. Our enzyme assays supported by biostructural analyses demonstrate that SETD3 has a broader substrate scope beyond histidine, including N‐nucleophiles on the aromatic and aliphatic side chains. Quantum mechanical/molecular mechanical molecular dynamics and free‐energy simulations provide insight into binding geometries and the free energy barrier for the enzymatic methyl transfer to histidine mimics, further supporting experimental data that histidine is the superior SETD3 substrate over its analogs. This work demonstrates that human SETD3 has a potential to catalyze efficient methylation of several histidine mimics, overall providing mechanistic, biocatalytic, and functional insight into actin histidine methylation by SETD3.
Subduction Erosion Revealed by Late Mesozoic Magmatism in the Gangdese Arc, South Tibet

Subduction of oceanic lithosphere can cause crustal growth and destruction, but whether this balancing act is common in a single fossil convergent system has been unclear. Here we report geochronologic‐geochemical‐isotopic data on Mesozoic igneous rocks in the central‐eastern Gangdese arc. Our results reveal: (a) A coupling of magmatic arc migration toward the continent interior with a marked incompatible enrichment of sub‐arc mantle magma sources; (b) numerous Late Cretaceous adakites were generated via combined partial melting of both eroded forearc crust debris and subducted oceanic crust; (c) the truncation of forearc crust and extremely short arc‐suture distance. Our work demonstrates that although there was significant vertical growth of juvenile crust throughout the Gangdese arc during the Late Mesozoic, a large amount of continental crust was returned back into the mantle through lateral subduction erosion at the same time. This study provides important insights into long‐term material recycling on Earth.
The Traveling Wave Solutions in a Mixed-Diffusion Epidemic Model

In this paper, we study the traveling wave solution of an epidemic model with mixed diffusion. First, we give two definitions of the minimum wave speeds and prove that they are equivalent. Second, the existence, decaying behavior, and uniqueness of traveling wave fronts are obtained. Third, the signs of minimum wave speeds are studied, and further, in two specific cases of the dispersal kernel, we show how to identify the signs of minimum wave speeds.
A cooperative routing algorithm for lifetime maximization in wireless sensor networks

In this paper, we study the impact of cooperative routing for maximizing the network lifetime in sensor network applications. We assume nodes in the network are able to perform cooperative transmission to achieve transmit diversity. We propose a joint cooperative transmission and energy conserving routing algorithm to prolong the network lifetime. First, a lifetime maximization problem via cooperative nodes is considered and performance analysis for MPSK modulation is provided. With an objective to maximize the minimum device lifetime under a constraint on bit-error-rate performance, the optimization problem determines which nodes should cooperate and how much power should be allocated for cooperation. Since the formulated problem is NP hard, a distributed suboptimal algorithm is developed for multi-node scenarios. We demonstrate through simulation that the proposed solution achieves 2~10 times longer network lifetime compared to non-cooperative routing, when it is used with FA algorithms.
Simulation of Winter Deep Slope Convection in Peter the Great Bay (Japan Sea)

In wintertime, a high-density water forms on the shallow shelf in the vast Peter the Great Bay (Japan Sea). The steep continental slope with deep canyons and cold winters in the area provide suitable conditions for the implementation of deep slope convection—an important phenomenon in the formation of intermediate and bottom waters that occurs at a few locations in some semi-enclosed seas, including the Japan Sea. The descent of dense shelf water down the continental slope of Peter the Great Bay usually occurs to 1000–1200 m; however, in anomalously cold winters, it has been observed at greater than 2000 m depth supporting renewal and deep ventilation of intermediate and bottom waters in the Japan Sea. The deep slope convection is a rare episodic phenomenon with durations ranging from several hours to several days, that has never been simulated in Peter the Great Bay with a realistic numerical model of circulation. We apply the Regional Ocean Modeling System (ROMS) with a 600 m horizontal resolution to simulate the deep slope convection in the anomalously cold winter of 2001 when it has been observed in cruises. The results are compared with propagation of deep shelf water in the regular winter of 2010 when hydrological characteristics of this water were recorded by a profiler “Aqualog” installed at the shelf break. Using Lagrangian methods, we track and analyze the formation of dense shelf water, its advection to the slope edge in the bottom layer and descent down the slope. Special attention is payed to the role of coastal eddies arising due to a symmetric instability. These eddies promote the cross-shelf transport of the dense shelf water towards the continental slope edge. The simulation results are compared with rare observations of the deep slope convection in Peter the Great Bay.
Relationship Between Preoperative Hypoalbuminemia and Postoperative Pneumonia Following Geriatric Hip Fracture Surgery: A Propensity-Score Matched and Conditional Logistic Regression Analysis

Background Pneumonia is a devastating complication following geriatric hip fracture surgery, and preoperative hypoalbuminemia may be a potentially modifiable factor leading to improved outcome. This study aimed to quantify the relationship between preoperative hypoalbuminemia and postoperative pneumonia. Methods We retrospectively reviewed the medical records of elderly patients (≥60 years) who underwent surgeries for hip fracture in a tertiary referral center between 2016 and 2020. According to the preoperative serum albumin level, they were divided into two groups: <35 g/ L and ≥35 g/ L. To reduce potential confounding, propensity score matching (PSM) in a 1:1 ratio was performed, with the caliper value set as 0.002; and further conditional logistic regression analysis was used to control the other potential confounders to determine the association strength. Results Among 3,147 eligible patients included, PSM yielded 1,318 matched patients, with 659 in each respective group, suggesting significantly improved balance in most variables (standardized mean deviation improvement range, 20.7% to 99.1%), except for basophil count. The conditional logistic regression analysis, adjusted for PS and other intra- or post-operative variables, showed 6.18-fold (relative ratio, 6.18; 95% CI, 3.15–11.98; P<0.001) increased risk of postoperative pneumonia associated with preoperative hypoalbuminemia. Conclusion Preoperative hypoalbuminemia was identified to be independently and highly associated with development of postoperative pneumonia in elderly patients undergoing hip fracture surgeries. However, whether the patients who had such condition may benefit from preoperative targeted nutritional support needs to be clarified by more prospective studies.
Employing the Defective Photonic Crystal Composed of Nanocomposite Superconducting Material in Detection of Cancerous Brain Tumors Biosensor: Computational Study

The present research is focused on the externally tunable defect mode properties of a one dimensional (1D) defective photonic crystal (DPhC) for fast detection of cancerous brain tumors. The proposed design has utilized conventional 1D DPhC whose cavity is coated with SiO2 nanoparticles embedded in a superconducting material layer called a nanocomposite layer. The purpose of a nanocomposite superconducting layer is to induce temperature dependent external tuning of the defect mode inside PBG, in addition, to changing in the angle of incidence. The inclusion of a nanocomposite layer also improves the interaction between light and different brain tissue samples under examination. In order to investigate the transmission properties of the proposed structure the transfer matrix formulation in addition to the MATLAB computational tool has been used. First, we have chosen the optimized internal parameters at normal incidence to obtain the maximum performance of the design. Secondly, the effect of change in angle of incidence has been studied to further increase the performance by means of sensitivity, quality factor, the figure of merit and limit of detection to ensure external tuning of defect mode. After achieving a maximum value of sensitivity (4139.24 nm/RIU) corresponding to a sample containing a wall of brain tissues at θ = 63° we have further investigated the effect of change in temperature of nanocomposite layers on the position and intensity both of the defect mode inside PBG. We have found that the increase in temperature results in minute changes in sensitivity but a significant increase in the intensity of defect mode which is highly required in any photonic biosensing design. The findings of this study may be very useful for designing various bio-sensing structures which could have a significant and decisive role in the field of biomedical applications.
Impact of Internal Corporate Governance Mechanism on Social Performance of Microfinance Institutions in Pakistan

ABSTRACT Purpose: The purpose of this research is to examine the impact of internal corporate governance mechanisms on the social performance of microfinance institutions of Pakistan. Design/Methodology/Approach: A survey questionnaire was used to collect data. Data were collected manually and online (Google survey form). The data collected were analyzed through Smart PLS. Findings: The results showed that board of directors, board meetings and frequency of board meetings as components of internal corporate governance mechanism have a positive and significant impact on the social performance of microfinance institutions of Pakistan. Implications/Originality/Value: The originality and contribution of this study is that this is the first study that analyzed the impact of board of directors, board meetings and frequency of board meetings as a component of internal corporate governance mechanism on the social performance of microfinance institutions of Pakistan.
Mannose Receptor-Mediated Carbon Nanotubes as an Antigen Delivery System to Enhance Immune Response Both In Vitro and In Vivo

Carbon nanotubes (CNTs) are carbon allotropes consisting of one, two, or more concentric rolled graphene layers. These can intrinsically regulate immunity by activating the innate immune system. Mannose receptors (MR), a subgroup of the C-type lectin superfamily, are abundantly expressed on macrophages and dendritic cells. These play a crucial role in identifying pathogens, presenting antigens, and maintaining internal environmental stability. Utilizing the specific recognition between mannose and antigen-presenting cells (APC) surface mannose receptors, the antigen-carrying capacity of mannose-modified CNTs can be improved. Accordingly, here, we synthesized the mannose-modified carbon nanotubes (M-MWCNT) and evaluated them as an antigen delivery system through a series of in vitro and in vivo experiments. In vitro, M-MWCNT carrying large amounts of OVA were rapidly phagocytized by macrophages and promoted macrophage proliferation to facilitate cytokines (IL-1β, IL-6) secretion. In vivo, in mice, M-MWCNT induced the maturation of dendritic cells and increased the levels of antigen-specific antibodies (IgG, IgG1, IgG2a, IgG2b), and cytokines (IFN-γ, IL-6). Taken together, M-MWCNT could induce both humoral and cellular immune responses and thereby can be utilized as an efficient antigen-targeted delivery system.
PENGARUH SERVANT LEADERSHIP TERHADAP KINERJA KARYAWAN MELALUI EMPLOYEE ENGAGEMENT DI RESTORAN SHABURI & KINTAN BUFFET SURABAYA

Company leaders are responsible for improving employee performance by increasing employee involvement on the job. The right leadership style enhances employee performance because it causes employees to feel motivated. This study aims to explain the influence of servant leadership on employee performance through employee engagement at Shaburi & Kintan Buffet Restaurants in Surabaya. This type of research is quantitative research, and research variables include servant leadership, employee engagement, and employee performance. The number of samples is 60 employees. The data collection techniques used a questionnaire. The data analysis technique used a structural equation model with the PLS. This study's findings indicate that servant leadership directly affects employee engagement but does not directly affect employee performance. On the other hand, employee engagement directly affects employee performance. Therefore, employee engagement is a variable that mediates the influence of servant leadership on employee performance. Abstrak Pimpinan perusahaan memiliki tanggung jawab meningkatkan kinerja karyawan dengan meningkatkan keterlibatan karyawan pada pekerjaan. Gaya kepemimpinan yang tepat dinilai akan mampu meningkatkan kinerja karyawan karena menyebabkan karyawan merasa termotivasi. Tujuan penelitian ini adalah menjelaskan pengaruh servant leadership terhadap kinerja karyawan melalui employee engagement pada Restoran Shaburi & Kintan Buffet di Surabaya. Jenis penelitian adalah penelitian kuantitatif, variabel penelitian meliputi: servant leadership, employee engagement, dan kinerja karyawan. Jumlah sampel sebanyak 60 karyawan. Teknik pengumpulan data menggunakan kuesioner. Teknik analisis data menggunakan structural equation model dengan program PLS. Temuan penelitian ini menunjukkan: servant leadership berpengaruh secara langsung terhadap employee engagement, tetapi tidak berpengaruh secara langsung terhadap kinerja karyawan. Employee engagement berpengaruh secara langsung terhadap kinerja karyawan. Employee engagement adalah variabel yang memediasi pengaruh servant leadership terhadap kinerja karyawan.