Miracle-dz/UniFAR-FTUs huggingface dataset:
Depression, anxiety and treatment satisfaction in the parents of children on antiretroviral therapy in South Africa

ABSTRACT Parents of children living with HIV are at increased risk of emotional distress, with negative implications for both their health outcomes. There is limited data on depression and anxiety symptoms in the biological parents as caregivers of children on antiretroviral therapy (ART) in South Africa. We investigated the prevalence and correlates associated with depressive and anxiety symptoms in 200 biological caregiving parents of children on ART at a public hospital in KwaZulu-Natal Province, South Africa. Data were obtained from the Patient Health Questionnaire (PHQ-9) for depressive symptoms and the Generalized Anxiety Depression (GAD-7) for anxiety symptoms, along with sociodemographic questionnaire. Most of the parent caregivers assessed were female (n = 190, 95%), younger than 40 years (n = 151, 75.5%), single (n = 173, 86.5%), unemployed (n = 156, 78%) and HIV+ (n = 183, 91.9%). Sixty-five (32.5%) parents screened positive for depression, 37 (18.5%) for anxiety and 31 (n = 31, 15.5%) for both disorders (i.e. depression/anxiety comorbidity). There were significant associations between death of a child to HIV (aOR = 4.66, 95% CI: 1.33–16.28) with depression/anxiety comorbidity as well as with treatment dissatisfaction (aOR = 13.98, CI: 2.09–93.66), but not with other socio-demographic factors. The high prevalence of depression and anxiety amongst the parent caregivers of children living with HIV suggests the need for mental health screening and care among parents of children attending pediatric HIV services, and particularly for those with history of children lost to HIV.
Interactions of Cortisol and Prolactin with Other Selected Menstrual Cycle Hormones Affecting the Chances of Conception in Infertile Women

One of the major problems of success in infertility treatment could depend on the understanding how the potential factors may affect the conception. The aim of this study was to evaluate present understanding of such factors or hormonal causes that may induce infertility. We studied the interactions between the two menstrual cycle hormones i.e., cortisol (COR) and prolactin (PRL), along with the ultrasonographic ovulation parameters in a group of N = 205 women with diagnosed infertility. The control group consisted of N = 100 women with confirmed fertility. In both groups, follicle-stimulating hormone (FSH), luteinizing hormone (LH), anti-Müllerian hormone (AMH), thyroid stimulating hormone (TSH), PRL, COR were examined on the third day of the cycle, and estradiol (E2), progesterone (P), and COR were examined during ovulation and 7-days afterwards. In the infertile group, higher levels of PRL and COR were observed than that of in the control group. Cortisol levels at all phases of the menstrual cycle and PRL negatively correlated with E2 secretion during and after ovulation, thus contributed to the attenuation of the ovulatory LH surge. Infertile women who conceived presented with higher levels of E2 during and after ovulation, higher P after ovulation, and thicker endometrium than that of the women who failed to conceive. In conclusion, elevated secretion of COR and PRL in infertile women impairs the menstrual cycle by decreasing the pre-ovulatory LH peak and E2 and postovulatory E2 levels that affect the endometrial growth, and consequently reduce the chances to conceive.
Subject Area : Accounting And Controlling RBGN Accounting Fraud : an estimation of detection probability

Financial statement fraud (FSF) is costly for investors and can damage the credibility of the audit profession. To prevent and detect fraud, it is helpful to know its causes. The binary choice models (e.g. logit and probit) commonly used in the extant literature, however, fail to account for undetected cases of fraud and thus present unreliable hypotheses tests. Using a sample of 118 companies accused of fraud by the Securities and Exchange Commission (SEC), we estimated a logit model that corrects the problems arising from undetected frauds in U.S. companies. To avoid multicollinearity problems, we extracted seven factors from 28 variables using the principal factors method. Our results indicate that only 1.43 percent of the instances of FSF were publicized by the SEC. Of the six significant variables included in the traditional, uncorrected logit model, three were found to be actually non-significant in the corrected model. The likelihood of FSF is 5.12 times higher when the firm’s auditor issues an adverse or qualified report.
Multi-Environment Analyses of Genetic Components and Combining Abilities in Relation to Heterosis in Okra [Abelmoschus esculentus (L.) Moench]

Okra (Abelmoschus esculentus (L.) Moench) is an economically important vegetable crop grown in tropical and sub-tropical parts of the world. India is a major okra producing country in the world comprising of 72% of total area under okra (FAOSTAT, 2013). Selection of suitable parents is an important step for enhancement of any breeding program for crop varietal improvement (Solankey et al., 2016). The knowledge of nature of gene action governing the expression of various traits could be helpful in predicting the effectiveness of selection (Dabhi et al., 2010). The combining ability is the important genetic tool, which provides a guideline for an assessment of the relative breeding potential of the parents or identifying the best combiners, which may be hybridized either to exploit heterosis or to accumulate fixable genes (Katagi et al., International Journal of Current Microbiology and Applied Sciences ISSN: 2319-7706 Volume 6 Number 12 (2017) pp. 2835-2842 Journal homepage: http://www.ijcmas. com
Principles of moral accounting: How our intuitive moral sense balances rights and wrongs

We are all saints and sinners: Some of our actions benefit others, while other actions lead to harm. How do people balance moral rights against moral wrongs when evaluating others' actions? Across 9 studies, we contrast the predictions of three conceptions of intuitive morality-outcome-based (utilitarian), act-based (deontologist), and person-based (virtue ethics) approaches. These experiments establish four principles: Partial offsetting (good acts can partly offset bad acts), diminishing sensitivity (the extent of the good act has minimal impact on its offsetting power), temporal asymmetry (good acts are more praiseworthy when they come after harms), and act congruency (good acts are more praiseworthy to the extent they offset a similar harm). These principles are difficult to square with utilitarian or deontological approaches, but sit well within person-based approaches to moral psychology. Inferences about personal character mediated many of these effects (Studies 1-4), explained differences across items and across individuals (Studies 5-6), and could be manipulated to produce downstream consequences on blame (Studies 7-9); however, there was some evidence for more modest roles of utilitarian and deontological processing too. These findings contribute to conversations about moral psychology and person perception, and may have policy and marketing implications.
Modulation of glucocorticoid action in vivo : role of lipid rafts and clocks

9 Declaration . 10 List of Abbreviations . 11 Chapter 1: Introduction . 18 1.1 Glucocorticoid Structure . 18 1.1.2 Glucocorticoid Synthesis and Release . 19 1.1.3 Glucocorticoid Physiology . 20 1.2 Glucocorticoid Receptor Structure . 22 1.2. 1 Activation Function-1 Domain . 23 1.2. 2 DNA Binding Domain . 24 1.2. 3 Ligand Binding Domain . 25 1.2. 4 Dimer Formation . 26 1.2. 5 Isoforms of the Glucocorticoid Receptor . 27 1.3. 1 Chaperones and Localisation of the Glucocorticoid Receptor . 28 1.3. 2 Nuclear Import of the Glucocorticoid Receptor . 30 1.3. 3 Post-translational Modifications of the Glucocorticoid Receptor . 31 1.4 Cellular Mechanisms of Action of the Glucocorticoid Receptor . 32 1.4. 1 Genomic Actions: Transactivation . 32 1.4. 2 Genomic Actions: Transrepression . 36 1.4. 3 Negative Glucocorticoid Response Elements . 37 1.4. 4 Protein-Protein Interactions: Tethering and Squelching . 38 1.4. 5 Tissue Specificity of Genomic Action . 40
Relationship between birth order, birth weight, colostrum intake, acquisition of passive immunity and pre-weaning mortality of piglets

This study investigates the relation between birth order (BO), birth weight (BW 0 ), colostrum intake (CI), level of passive immunity and pre-weaning mortality of piglets. The animals used were 551 cross-bred piglets [Pietrain × (Large-White × Landrace)] born from 40 sows. Colostrum immunoglobulins G (IgG) determinations were made from 17 sows. Colostrum samples were obtained at birth of the first piglet then at 3, 6, 12, 24, and 36 h later, and on the first-two and the last-two piglets born. Serum IgG determinations from 68 piglets were made at 2d of age and at weaning. Individual CI was estimated from body weight gain. Relative birth order (RBO) and BW 0 within-litter were weakly ( R 2 0.10) but increased by 26 ± 1.6 g per 100 g increase in BW 0 ( p 0.10). It was concluded that despite last-born piglets obtained less passive immunity than first-born, they were not at higher risk of dying before weaning. Major causes of mortality were low birth weight and insufficient colostrum (energy) intake.
In silico approaches towards the exploration of rice bran proteins-derived angiotensin-I-converting enzyme inhibitory peptides

ABSTRACT Rice bran is an important underutilized by-product of rice-processing industries, and a huge amount of bran is released during rice processing. It can be used as a prime source of bioactive peptides towards the development of functional food ingredients. The aim of the study was to evaluate the potential of rice bran proteins such as glutelin, globulin, and prolamin as a precursor of bioactive peptides using various in silico approaches (BLAST, BIOPEP, PeptideRanker, PepDraw, Pepcalc, and ToxinPred). Rice bran proteins majorly release angiotensin-I-converting enzyme (ACE) and dipeptidyl peptidase IV (DPP-IV) inhibitory peptides. Papain protease can cleave the rice bran proteins effectively compared with other proteases to release ACE-inhibitory peptides. Physicochemical studies have shown that ACE-inhibitory peptides have low molecular weight profiles. These peptides have been classified as bitter peptides with a non-toxic profile. The result of this study demonstrates the usefulness of in silico approaches and provides a theoretical basis for the development of rice bran proteins as a source of bioactive peptides. The predicted prominent ACE-inhibitory peptides could be used for the development of functional food products or nutraceuticals.
The architecture of an intrusion in magmatic mush

<p class="western" align="justify"><span lang="en-US">Magmatic reservoirs located in the upper crust have been shown to result from the repeated intrusions of new magmas, and spend most of their dwelling time as cristal-rich mush. Despite advances in our understanding of the physical processes that may occur in a magma reservoir, the architecture of the intrusion into a mush remains poorly constrained. The geometry of such intrusions, however, may greatly affect the thermal and compositional evolution of the magmatic reservoir. We performed numerical simulations coupling computational fluid dynamics with the discrete element method to identify the geometry and emplacement dynamics of an intrusion in a mush, and the relevant physical parameters controlling it. Our results show that the intrusion geometry is to first-order controlled by the density contrast between the melt phases of the intruded and resident materials rather than the bulk density contrast as usually considered. When the melt phase of the intruded materials is denser than that of the host, the intrusion ponds at the base of the mush and is emplaced as a horizontal layer. However, when the intruded melt is lighter, the intrusion rises through the mush forming a Rayleigh&#8211;Taylor instability. In the absence of density contrast between the two melts, the intrusion fluidizes the host crystal network and slowly ascends through the mush. The presence of a viscosity contrast between the intruded and resident materials as well as the intrusion injection velocity were found to have less of an influence on the final geometry and intrusion dynamics in mush. In addition, we analyzed the eruptive sequence of well documented eruptions involving an intrusion as a trigger, and found good agreement with our modeling results. This study sheds light on the importance of explicitly considering granular mechanisms and the relative motion between the crystals and the melt phase when studying the physical processes of magmas and mush. </span></p>
Tiller Size and Water Table Effects in Celery Growth on Floating Cultivation System

Riparian wetland is highly available and potential suboptimal lands for an alternative solution in extending agricultural activity, but several constrains need to be resolved. The objective of this study was to improve the diversification of vegetables for increasing riparian wetland with utilizing floating cultivation system. This study was conducted From November until December 2019 in Jakabaring (104°46’4” E; 3°01’35” S) Palembang. The design of experiments used in this study was arranged in split plot-completely randomized design with 2 factors (main plot and sub-plot). Main plot was the height of water table, 185 Jaya et al.: Tiller Size and Water Table Effects in Celery Growth namely: R1 (1 cm upper raft surface), R5 (5 cm upper raft surface), and R10 (10 cm upper raft surface). Sub-plot was the size of celery tiller, i.e., B1 (big size) and B2 (small size). Each combination treatment consisted of five replication. Results showed that there was no any significant effect on water table and tiller size combination treatments in all observed variables, such as: plant height, leaf area, number of petioles, root length, fresh weight, and dry weight of shoot and roots. But, root length was significant different in water table treatment. Therefore, cultivated celery using floating culture system from tiller of parent plants can be an alternative to increase agriculture activity by shortening the planting period to increase vegetable diversification in riparian wetland.
Photorefractive Solitons

1 Dipartimento di Fisica, Università dell’Aquila, 67010 L’Aquila, Italy and Istituto Nazionale Fisica della Materia UdR Roma ”La Sapienza”, 00185 Roma, Italy eugenio.delre@aquila.infn. it 2 Physics Department, Technion, Haifa, Israel msegev@tx.technion. ac.il 3 School of Optics-CREOL, University of Central Florida, Orlando, 32816-2700 United States demetri@creol.ucf. edu 4 Physics Department, University of Arkansas, Fayetteville, 72703-0000 United States salamo@uark.edu
COMPARISON OF ACTIVE ISOLATED STRETCH AND POST ISOMETRIC RELAXATION FOR IMPROVING HAMSTRING FLEXIBILITY IN YOUNG HEALTHY ADULTS

Objective: To compare the immediate, short term and long term effects of active isolated stretch versus post isometric relaxation on hamstring flexibility in young healthy adults. Study Design: Randomized controlled trial (trail number is NCT04024839). Place and Duration of Study: Islamabad Federal College, in the department of Doctor of Physical Therapy from Jan 2018 to Jul 2018. Methodology: Thirty five students were selected according to inclusion criteria and randomly assigned into two groups by lottery method 17 and 18 in each group respectively. Group A was given post isometric relaxation while group B was active isolated stretch. Age group between 18 to 25 year, male and female students with tight hamstring were included while neurological and orthopedic disorders were excluded. Active Isolated Stretch and Post Isometric Relaxation at baseline, after first and final exercise session were calculated immediately and short term effects while long term effects were calculated after two weeks of final session. Results: Active knee extension score for both hamstring muscles after 1st session showed statistical insignificant improvement for both legs (p=0.20 right and p=0.18 left). Active knee extension score after 2 weeks of exercises gave insignificant improvement in score for both legs (p=0.20 right and p=0.20 left). Similarly, Active Knee Extension score after all sessions showed insignificant improvement for both legs (p=0.49 right and p=0.88 left). There was no significant improvement for Active Knee Extension, lower extremity scale and sit and reach test with p=0.15. There were no differences between the effectiveness of both techniques i.e., Passive Isometric Relaxation and Active Isolated Stretch (p=0.58). Conclusion: Both techniques were equally effective in their immediate, short-term and long term effects on hamstrings flexibility.
Computational Model of Artificial Neural Networks and its Applications in Data Mining

Data remain a very important ingredient required by any organization to make informed decision as it affects operations. Companies have been collecting data from various sources over the decades bringing about a very large volume of data warehouse. Unfortunately, most organizations build databases which are redundant and never used for any meaningful thing. While few companies use the data collected in their databases when taking strategic decisions others barely do same. However, for an organization to immensely derive benefits from the massive data warehouse, there is the need for an effective and efficient means of analysing the data with a view to extracting meaningful knowledge that is sufficient to achieve organizational goal. To achieve this, Artificial Neural Network (ANN) technique through the concept known as data mining is presented. The paper reviewed artificial neural network technique for data mining, examines the computational model behind this technique and analysed its use and application as a predicting or forecasting tool. Results shows that ANN’ has capability in data management, analysis and able to provide desirable knowledge for management decision making processes. It is therefore recommended that data mining tools like ANN and others be applied to organization’s databases which hitherto have not been minned in order to provide management with intelligence for decision making
Countering DDoS Attacks in SIP Based VoIP Networks Using Recurrent Neural Networks

Many companies have transformed their telephone systems into Voice over IP (VoIP) systems. Although implementation is simple, VoIP is vulnerable to different types of attacks. The Session Initiation Protocol (SIP) is a widely used protocol for handling VoIP signaling functions. SIP is unprotected against attacks because it is a text-based protocol and lacks defense against the growing security threats. The Distributed Denial of Service (DDoS) attack is a harmful attack, because it drains resources, and prevents legitimate users from using the available services. In this paper, we formulate detection of DDoS attacks as a classification problem and propose an approach using token embedding to enhance extracted features from SIP messages. We discuss a deep learning model based on Recurrent Neural Networks (RNNs) developed to detect DDoS attacks with low and high-rate intensity. For validation, a balanced real traffic dataset was built containing three attack scenarios with different attack durations and intensities. Experiments show that the system has a high detection accuracy and low detection time. The detection accuracy was higher for low-rate attacks than that of traditional machine learning.
Cadmium Toxicity Alleviates by Seed Priming with Proline or Glycine Betaine in Cowpea ( Vigna unguiculata (L.) Walp.)

CADMIUM (Cd) as a non-essential metal is a soil pollutant that inhibits plant growth and development. Proline (Pro) and Glycine betaine (GB) are two important compatible solutes that accumulate in response to abiotic stresses in different plant species. Here, a pot experiment was carried out to assess the role of exogenously applied Pro and GB in improving Cd toxicity tolerance in cowpea plants. Seeds were soaked in 0, 25 and 50mM Pro or GB, and then were sown in plastic pots that were irrigated with 0 or 100μM cadmium chloride. Results showed that Cd stress markedly decreased shoot length, shoot biomass, leaf area, chlorophyll value, stomatal conductance and relative water content (RWC) but increased root and shoot Cd levels, malondialdehyde (MDA) content and antioxidant enzyme activities such as superoxide dismutase (SOD), catalase (CAT) and ascorbate peroxidase (APX). Nevertheless, seed treatment with Pro or GB reduced Cd toxicity and improved growth attributes via reducing Cd uptake and translocation, increasing the chlorophyll value, stomatal conductance, and RWC as well as more enhancing the activities of antioxidant enzymes and lowering the MDA level. Although both Pro and GB were effective, pre-treatment of seeds with Pro improved Cd stress tolerance better than GB. Thus, seed treatment with Pro (especially 50mM) could be used as an effective method for protecting cowpea plants against Cd toxicity.
Effect of Radiofrequency Electromagnetic Fields on Thermal Sensitivity in the Rat

The World Health Organization and the French Health Safety Agency (ANSES) recognize that the expressed pain and suffering of electromagnetic field hypersensitivity syndrome (EHS) people are a lived reality requiring daily life adaptations to cope. Mechanisms involving glutamatergic N-methyl d-aspartate (NMDA) receptors were not explored yet, despite their possible role in hypersensitivity to chemicals. Here, we hypothesized that radiofrequency electromagnetic field (RF-EMF) exposures may affect pain perception under a modulatory role played by the NMDA receptor. The rats were exposed to RF-EMF for four weeks (five times a week, at 0 (sham), 1.5 or 6 W/kg in restraint) or were cage controls (CC). Once a week, they received an NMDA or saline injection before being scored for their preference between two plates in the two-temperatures choice test: 50 °C (thermal nociception) versus 28 °C. Results in the CC and the sham rats indicated that latency to escape from heat was significantly reduced by −45% after NMDA, compared to saline treatment. Heat avoidance was significantly increased by +40% in the 6 W/kg, compared to the sham exposed groups. RF-EMF effect was abolished after NMDA treatment. In conclusion, heat avoidance was higher after high brain-averaged specific absorption rate, affording further support for possible effect of RF-EMF on pain perception. Further studies need to be performed to confirm these data.