Miracle-dz/UniFAR-FTUs huggingface dataset:
Rice NIN-LIKE PROTEIN 1 Rapidly Responds to Nitrogen Deficiency and Improves Yield and Nitrogen Use Efficiency

Nitrogen (N) is indispensable for crop growth and yield, but excessive agricultural application of nitrogenous fertilizers has generated severe environmental problems. A desirable and economical solution to cope with these issues is to improve crop nitrogen use efficiency (NUE). Plant NUE has been a focal point of intensive research worldwide, yet much more has to be learned about its genetic determinants and regulation. Here, we show that rice NIN-LIKE PROTEIN 1 (OsNLP1) plays a fundamental role in N utilization. OsNLP1 protein localizes in nucleus and its transcript level is rapidly induced by N starvation. Overexpression of OsNLP1 improves plant growth, grain yield and NUE under different N conditions while knockout of OsNLP1 impairs grain yield and NUE under N limiting conditions. OsNLP1 regulates nitrate and ammonium utilization by cooperatively orchestrating multiple N uptake and assimilation genes. Chromatin immunoprecipitation and yeast-one-hybrid assays show that OsNLP1 can directly bind to the promoter of these genes to activate their expression. Therefore, our results demonstrate that OsNLP1 is a key regulator of N utilization and represents a potential target for improving NUE and yield in rice. One-sentence summary OsNLP1 rapidly responds to N availability, enhances N uptake and assimilation, and holds great potential in promoting high yield in rice.
The effect of conocarpan on susceptibility of Candida albicans to phagocytosis and digestion by macrophages

Piper solmsianum C. DC. compounds exhibit several properties, including antimicrobial activity. The aim of the present study was to investigate whether conocarpan alters Candida albicans growth or killing of the yeast by macrophages. Conocarpan showed strong activity against the yeast with minimal inhibitory concentration (MIC) of 20 µg/mL and minimal fungicidal concentration (MFC) of 30 µg/mL. Mice peritoneal cells (macrophages) were cultured for 24 and 48 hours in supplemented RPMI 1640 medium. Cellular activation was assessed by determining MTT reduction and nitric oxide production. Standardized tests were conducted to select the optimal parameters for the subsequent killing test. Results showed that conocarpan exhibited antifungal activity and that C. albicans cultivated in the presence of the compound had greater susceptibility to death by macrophages. These findings suggest that conocarpan may have potential as an antimicrobial agent for C. albicans infections, promoting macrophagic immune support by altering growth of the yeast.
Petrogenetic aspects and role of liquid immiscibility from parts of eastern Deccan volcanic province, India

One atmosphere experimental studies have been conducted on two amygdule‐free representative samples from Khandwa, Madhya Pradesh, Central India, belonging to Eastern Deccan Volcanic province in order to understand mineral petrogenesis, crystallization history of the parent magma and role of liquid immiscibility. One atm experiments were carried out on these two samples at specified temperatures on designated time in order to understand crystallization history. The run products were identified both by optical means and electron microprobe analysis. The identified run products include pyroxenes, feldspar, opaques phase (oxide and sulphide), silica phases, and glass (both brown and colourless variety). The run product pyroxenes belong to quadrilateral pyroxene, and species‐wise correspond to augite, clinoenstatite, and pigeonite. Feldspars in majority are found to be anorthoclase (which are interpreted to have been formed during sudden crystallization in contact with water at shallow depth during experiments) and less commonly calcic plagioclase (in the range of labradorite to anorthite). Opaque phases have both oxide and sulphide, namely hematite, magnetite, martite, and pyrite, respectively. The zoned nature between the oxide and sulphide phases is suggestive of oscillation of oxygen fugacity during crystallization. The run product silica phase corresponds to tridymite. The silica‐rich glass (colourless) is overwhelmingly dominant, whereas silica‐poor glass (brown glass) is a manifestation of liquid immiscibility. The silica‐rich glasses give rise to direct crystallization of tridymite, whereas silica‐poor glasses act as the main driving liquid (or parent liquid) to further the crystallization towards lower temperature. The crystallization behaviour of the parent magma, and liquid immiscibility can be well documented with reference to forsterite‐silica phase diagram; in this phase diagram, the parent liquid corresponds to normative Qtz: 2.542, Fo: 0.098, and En: 0.34. The ambient parent liquid plots very close to Ab apex with reference to the Di‐Ab‐An phase diagram. The clear and distinct zonation pattern present in the opaque phases signifies that crystallization straddles between both oxidizing and reducing condition yielding crystallization of both oxide and sulphide phases. Our study indicates a unique role of liquid immiscibility of the parent magma supplemented by oscillation of oxidizing and reducing conditions giving rise to ensemble of variety of glass compositions, silicate, and opaque phases.
Event-Triggered Bipartite Consensus for Multiagent Systems: A Zeno-Free Analysis

In this article, the bipartite consensus of first-order multiagent systems with a connected structurally balanced signed graph is studied. To reduce the communications among agents, a distributed event-triggered control law is proposed, where the event-triggering condition of each agent only uses its own state and the sampled states of its neighbours, and no knowledge of the global network topology is required. By relating to the nonexistence of some finite-time convergence, a novel analysis is given to show that there is no Zeno behavior in the proposed event-triggered multiagent system. Then, from the Lyapunov stability theory and the algebraic graph theory, it is proved that all agents can reach agreement with an identical magnitude but opposite signs. Finally, a numerical example is given to illustrate the efficiency and feasibility of the proposed results.
Eco-anxiety and the flight shaming movement: implications for tourism

Purpose: This paper aims to briefly discuss the flight shaming (flygskam) movement and considers its implications for tourism. Design/methodology/approach: The paper synthesises the current thinking on the flight shaming movement and contextualises it for tourism futures. Findings: While flygskam is unlikely to become mainstream in the near future, it is imperative that the air travel industry respond more comprehensively to changing attitudes in the market. Originality/value: This trends paper addresses a topical debate in the current environmental public discourse, highlighting the negative emotional states (eco-anxiety) associated with concerns about climate change.
A note on a class of B\^ochner-Riesz multipliers

For a general compact variety $\Gamma$ of arbitrary codimension, one can consider the $L^p$ mapping properties of the Bochner-Riesz multiplier $$ m_{\Gamma, \alpha}(\zeta) \ = \ {\rm dist}(\zeta, \Gamma)^{\alpha} \phi(\zeta) $$ where $\alpha > 0$ and $\phi$ is an appropriate smooth cut-off function. Even for the sphere $\Gamma = {\mathbb S}^{N-1}$, the exact $L^p$ boundedness range remains a central open problem in Euclidean Harmonic Analysis. In this paper we consider the $L^p$ integrability of the Bochner-Riesz convolution kernel for a particular class of varieties (of any codimension). For a subclass of these varieties the range of $L^p$ integrability of the kernels differs substantially from the $L^p$ boundedness range of the corresponding Bochner-Riesz multiplier operator.
Drosophila melanogaster: A Robust Tool to Study Candidate Drug against Epidemic and Pandemic Diseases

Drosophila melanogaster is a widely used, dynamic model organism to study various pathogenic diseases observed ubiquitously in the human population. Drosophila, at present, is extensively used to conduct preclinical studies besides its counterpart rodents. The epidemic and pandemic diseases are discussed in this review to demonstrate Drosophila melanogaster as a key model. Epidemic and pandemic diseases are still claiming more than 5 million lives every year, and these diseases were well studied in flies. Currently there is no cure for the disease like HIV; the bacterial and fungal infections usually seen in HIV/AIDS patients could be demonstrated elaborately in Drosophila melanogaster . Diseases like myocardial infractions and cancer causing viral infection are long term effects of ART (anti-retroviral therapy) that could be experimented in flies. Stable Drosophila S2 cell line, Transgenic flies, transfusion of bacteria and fungi could be implemented to study several infectious diseases and for vaccine development. The latest trends in understanding pathogenic diseases and its potential biochemical markers in flies are discussed in this review to utilize the fruit flies as a functional tool and to explore further it in drug development. The advantages and disadvantages of the fly as a model of infection are discussed along with the epidemiology and the cellular pathophysiology
Geração de Resíduos de Serviços de Saúde em hospitais do município de Ribeirão Preto (SP), Brasil Generation of Medical Waste in hospitals in the city of Ribeirão Preto (SP), Brazil

ABSTRACT This research aimed to identify the generation of healthcare waste in hospitals in the city of Ribeirao Preto (SP). This is a descriptive and exploratory study conducted in 11hospitals in the city. Data were collected through of the weighing of the MW and were after approval of hospitals and approval by the of Ethics Committee Research of the EERP/USP. The 11hospitals included in the study had a generation of 44,489.91 kg of healthcare waste at 6 days, with a daily average of 7,414.98 -1 . The data obtained revealed a kg.daygeneration of 29,846.08 kg (67.1%) of common residues (Group D); and 11,236.69 kg (25.3%) of infectious waste and sharps (Groups A and E). This study reinforces the need for adequate healthcare waste management for the reduction of generation in any situation, especially in hospitals.Keywords: healthcare waste; waste management; environmental health; public health. INTRODUCAO A Agencia Nacional de Vigilância Sanitaria (Anvisa), por meio da RDC no 306/2004, considera como Residuos de Servicos de Saude (RSS) aqueles gerados em qualquer servico prestador de assistencia medica, sanitaria ou estabelecimentos congeneres, provenientes de hospitais, unidades ambulatoriais de saude, clinicas e consultorios medicos e odontologicos, farmacias, laboratorios de analises clinicas e patologicas, bancos de sangue e de leite e clinicas veterinarias, entre outros (BRASIL, 2004). O Conselho Nacional do Meio Ambiente (CONAMA), por meio da Resolucao no 358/2005, em consonância com a RDC no 306/2004, define como geradores de RSS todos os servicos relacionados aos aten ‑dimentos a saude humana ou animal, inclusive aqueles de assistencia domiciliar e de trabalhos de campo, bem como laboratorios de produtos para saude, necroterios, funerarias e servicos onde se realizam ativida ‑des de embalsamamento (tanatopraxia e somatoconservacao), dentre outros similares (BRASIL, 2005; TAKAYANAGUI, 2004). Essas duas normativas nacionais classificam os RSS em cinco Grupos, de acordo com suas caracteristicas. No Grupo A incluem‑se os residuos biologicos; no Grupo B, residuos de origem quimica; no Grupo C, rejeitos radioativos; no Grupo D, residuos comuns; e, no Grupo E, os materiais perfurocortantes (BRASIL, 2004). Para Gomes e Esteves (2012), os RSS representam um serio pro‑blema para a sociedade e para o ambiente devido as suas caracteristicas toxicas e/ou patogenicas. Portanto ha uma preocupacao mundial no que se refere ao gerenciamento dos RSS, fazendo com que as normativas DOI: 10.1590/S1413-41520201600100140092
Prevalence of Pulmonary Tuberculosis among Illicit Injecting Drug Users of Karachi, Pakistan

Tuberculosis is endemic and is a major public health challenge in Pakistan. Illicit drug users continue to be a group at high risk for tuberculosis (TB). Drug users and injection drug users in particular, have driven TB epidemics in a number of countries including Pakistan. The successful identification and treatment of TB among illicit drug users remain important components of a comprehensive TB strategy, but illicit drug users present a unique set of challenges for TB diagnosis and control due to their exposure to risk factors like HIV Infection, homelessness, health disparities and other negative socio-economic factors poverty among them. In this study we aimed to determine the prevalence of Tuberculosis among injecting Drug Users (IDUs) in Karachi, Pakistan. A descriptive cross sectional study was conducted, in the year 2015 in two towns of Karachi (Kimari and Saddar), Pakistan. Trained investigators used a standardized multiple-choice and open-ended questionnaire to collect the data regarding demographic profile of the respondents, injecting practices and other related information to identify Tuberculosis suspects. Written informed Consent was obtained and questionnaire was completed by 155 injection drug user (IDUs) selected through proportionate stratified sampling. The sputum samples were collected as per guidelines of National TB Control Program from identified TB suspects. The data were analysed using IBM SPSS Statistics version 20.0 and Microsoft excel. There were 151 men (97%), 3 female (2%) and 1 (1%) transgender among participants. In our study prevalence of TB among IDUs was 12% and most (72%) of them were living on street and 46 (30.9%) were married, therefore making their spouses and family members a high risk group for TB. The prevalence of Tuberculosis among injecting illicit drug users is 12%. Future research needs to be directed toward this sensitive issue and social support programs with treatment services should be ensured for TB positive IDUs living on streets to reduce the disparities in provision of health services for this vulnerable stratum of our society.
A Text Mining Analysis of Central Bank Monetary Policy Communication in Nigeria

This paper employs text-mining techniques to analyse the communication strategy of the Central Bank of Nigeria (CBN) during the period 2004-2019. Since the policy communique released after each meeting of the CBN’s monetary policy committee (MPC) represents an important tool of central bank communication, we construct a corpus based on 87 policy communiques with a total of 123, 353 words. Having processed the textual data into a form suitable for analysis, we examined the readability, sentiments, and topics of the policy documents. While the CBN’s communication has increased substantially over the years, implying increased monetary policy transparency; the computed Coleman and Liau readability index shows that the word and sentence structures of the policy communiques have become more complex, thus reducing its readability. In terms of monetary policy sentiments, we find an average net score of -10.5 per cent, reflecting the level of policy uncertainties faced by the MPC over the sample period. In addition, our results indicate that the topics driving the linguistic contents of the communiques were influenced by the Bank’s policy objectives as well as the nature of shocks hitting the economy per period.
Assessment of a pluralistic advisory system: the case of Madhupur Sal Forest in Bangladesh

ABSTRACT Purpose: Participatory forest management initiatives in Madhupur Sal Forest in Bangladesh are characterized by the coexistence of diverse types of advisory service providers. Despite a decade of implementation of forest management initiatives, an assessment of the service delivery from a pluralistic advisory service framework is not evident. Drawing on the framework of pluralistic advisory service this study aimed to assess the role and performance of different advisory service providers that contribute to the management of forest resources. Methodology: We employed a stakeholder analysis to identify different advisory service providers, along with their power relations with forest dwellers. Data were collected using a participatory workshop and nine interviews. Findings and practical implications: The study found that most of the advisory service providers did not ensure the quality of the services, and did not orient their services towards the needs and demands of the forest dwellers. The advisory service providers continued to work with a coordination gap among themselves and the forest dwellers, which ultimately hindered their collective efforts to mobilize resources and build the strong relational condition necessary for the proper management of forest resources. Theoretical implications: This study applied a ‘best fit’ framework to the micro-level case of a forest advisory service, which helped to explore the dynamics of an advisory system linked to forest management initiatives. Originality: This is the first attempt to assess a pluralistic advisory system for forest management in Bangladesh.
CHARACTERIZATION OF EDIBLE FILM BASED ON DIFFERENT RATIOS OF κ-CARRAGEENAN/GELATINE WITH THE ADDITION OF CANOLA OIL

κ-carrageenan/gelatin mixtures and canola oil can form an emulsion film when they are well combined and can mediate the release of volatile substances. The objectives of this study were: 1) to investigate the effect of different ratios of κ-carrageenan/gelatin with and without the addition of canola oil on moisture content, solubility, thickness, water vapor transmission rate, tensile strength and percent elongation, 2) to study the release of ethyl acetate with different ratios of κ-carrageenan/gelatin with added canola oil. Edible films were prepared with varying ratios of κ-carrageenan/gelatin with and without the addition of canola oil. Ethyl acetate release from selected films was also observed. The results showed that different ratios of κ-carrageenan/gelatin with canola oil addition induced changes in moisture content, thickness, water vapor transmission rate, and tensile strength (p<0.05). A significant decrease in the water vapor transmission rate of films was induced by canola oil with a ratio of κ-carrageenan/gelatin of 1.35:1.65. In addition, κ-carrageenan/gelatin at a ratio of 1.35:1.65 with added canola oil triggered a larger release of ethyl acetate. These findings confirmed that different ratios of κ-carrageenan/gelatin with canola oil could be used to tailor emulsified films with enhanced barrier properties and to trigger the release of volatile substances.
Global Change Can Make Coastal Eutrophication Control in China More Difficult

Fast socio‐economic development in agriculture and urbanization resulted in increasing nutrient export by rivers, causing coastal eutrophication in China. In addition, climate change may affect hydrology, and as a result, nutrient flows from land to sea. This study aims at a better understanding of how future socio‐economic and climatic changes may affect coastal eutrophication in China. We modeled river export of total dissolved nitrogen (TDN) and phosphorus (TDP) in 2050 for six scenarios combining socio‐economic pathways (SSPs) and Representative Concentration Pathways (RCPs). We used the newly developed MARINA 2.0 (Model to Assess River Inputs of Nutrients to seAs) model. We found that global change can make coastal eutrophication control in China more difficult. In 2050 coastal waters may be considerably more polluted or considerably cleaner than today depending on the SSP‐RCP scenarios. By 2050, river export of TDN and TDP is 52% and 56% higher than in 2012, respectively, in SSP3‐RCP8.5 (assuming large challenges for sustainable socio‐economic development, and severe climate change). In contrast, river export of nutrients could be 56% (TDN) and 85% (TDP) lower in 2050 than in 2012 in SSP1‐RCP2.6 (assuming sustainable socio‐economic development, and low climate change). Climate change alone may increase river export of nutrients considerably through hydrology: We calculate 24% higher river export of TDN and 16% higher TDP for the SSP2 scenario assuming severe climate change compared to the same scenario with low climate change (SSP2‐RCP8.5 vs. SSP2‐RCP2.6). Policies and relevant technologies combining improved nutrient management and climate mitigation may help to improve water quality in rivers and coastal waters of China.
Polycystic ovarian syndrome and pregnancy outcome

In a developing country like ours, which is the diabetic capital of the world, Polycystic ovary syndrome (PCOS) is one of the top listed endocrine disorders in women between 13 to 40 years of reproductive age. Prevalence of the disease is between 5 to 10%. Stein and Levinthal was the first to describe the condition. Rotterdam ESHRE/ASRM in the year 2003 standardized the definition of PCOS, which is characterized by a combination of oligomenorrhea / amenorrhea, clinical or endocrine signs of hyperandrogenemia and polycystic ovaries. 70% of the women suffer from normogonadotrophic anovulation, but with the presence of the ultrasound or endocrine features of PCOS. More than 50% of women diagnosed with PCOS are overweight or obese. This metabolic disorder is most commonly associated with infertility. 15-20% of the ABSTRACT
Complete mitochondrial genome of the jellyfish, Chrysaora pacifica (Goette, 1886) (Cnidaria, Scyphozoa) and the phylogenetic relationship in the related species

Abstract The complete mitochondrial genome sequences of giant jellyfish Chrysaora pacifica, a scyphozoan species inhabiting the Bohai Sea water in China, is firstly described and analyzed in this research. The mitogenome is a circular molecule 16,964 bp in length, including 13 protein-coding genes (Cox 1, Cox2, Atp 8, Atp 6, Cox 3, ND2, ND5, ND 6, ND3, ND4L,ND1,ND4, Cob), 2 tRNAs (trnW, trnM), 2 rRNA genes (small subunit RNA and large subunit RNA). The neighbor-joining (NJ) phylogenetic tree in the related species showed that C. pacifica is close to Chrysaora quinquecirrha.
Bahasa Remun di Negeri Sarawak: Kajian Perbandingandengan Bahasa Iban

Bahasa Ibanik adalah cabang bahasa Melayik yang variasinya memaparkan inovasi *-an, *- ang dan *-ar kepada /-ay/. Cabang bahasa ini tersebar di Kalimantan Barat (Indonesia) dan Sarawak (Malaysia). Di Sarawak, hanya variasi bahasa Ibanik Iban sahaja yang dikenali umum. Bahasa Remun yang turut merupakan variasi Ibanik sebaliknya kurang mendapat perhatian sarjana. Melalui tinjauan kosa ilmu mendapati bahawa belum ada deskripsi linguistik intensif yang membincangkan hubungan antara bahasa Remun dan bahasa Iban. Kajian ini menerapkan pendekatan deskriptif untuk mencungkil persamaan dan perbezaan kedua-dua bahasa ini dengan berfokus kepada aspek leksikal dan fonologi. Daripada 150 sampel kosa kata yang dibandingkan, didapati kadar persamaan kosa kata untuk kedua-dua bahasa ini ialah 82%. Melalui analisis fonologi ke atas dua fonem, iaitu r dan s didapati bahawa fonem r wujud sebagai /ɣ/ dalam bahasa Remun manakala sebagai /r/ dalam bahasa Iban. Bagi fonem s, bunyi ini wujud sebagai /h/ pada posisi akhir kata Remun dan sebagai /s/ dalam bahasa Iban. Analisis fonologi ini telah memberi bukti tambahan bahawa bahasa Remun bukanlah sejenis dialek Iban walaupun memaparkan persamaan 85% kognat. Hasil kajian ini dapat meningkatkan kesedaran badan perancang bahasa Iban di Sarawak tentang wujudnya kelainan variasi dalam bahasa berkenaan. Justeru kerana bahasa Iban Standard turut diajar sebagai matapelajaran teras dalam pendidikan di Sarawak, kelainan-kelainan ini wajar diberi perhatian untuk melancarkan pembelajaran bahasa Iban.