Miracle-dz/UniFAR-FTUs huggingface dataset:
Modulation of thermal resistance of ascospores of Neosartorya fischeri by acidulants and preservatives in mango and grape juice

Abstract Minimal thermal processing is desirable for near natural organoleptic and nutritional qualities of fruit based products. In the present investigation, the effect of heat (85°C) in combination with acidulants or common preservatives on inactivation of ascospores of Neosartorya fischeri , a heat resistant mould isolated from grapes, has been studied in mango and grape juice. The ascospores were found to survive for >300 min of heating at 70, 75 and 80°C in these fruit juices and complete inactivation required 120 min of heating at 85°C. The synergistic effect of heat and organic acids or preservatives in fruit juices was noticed. The thermal death rate (1/k 85°C ) values did not vary much in the presence of lactic (20), malic (20) and citric (19) acids, but tartaric acid showed least inactivation effect (1/k 85°C =54 min) in mango juice. The 1/k 85°C values for ascospores of N. fischeri in mango juice containing 0·1% of potassium sorbate or sodium benzoate or combination of both at 0·05% were found to be 44, 35 and 29 min respectively. These values were respectively, 32, 13 and 14 min in grape juice. Nearly 50 and 67% of the heating time was reduced by the use of potassium sorbate and sodium benzoate (0·05% each) in mango and grape juice to inactivate 3 log number of ascospores of N. fischeri . These results may be useful in thermal processing of fruit juices.
Temporal Dynamics of Jellyfish Pelagia noctiluca Stranded on the Mediterranean Coast of Morocco

Seasonal dynamics of the scyphomedusa Pelagia noctiluca were studied along with their relation to certain environmental factors between the study period that extends from January 2018 to December 2019. During 2018, stranded individuals of P. noctiluca appeared throughout this year, but their high frequency was reported in the summer . While in contrast, P. noctiluca in 2019 was reported in a very low number only during the winter season and had not been detected in the other seasons of this year. The overall results revealed that the inter-annual variations in the abundance of jellyfish were not significantly (P<0.05) correlated with water temperature, relative humidity and atmospheric pressure. Our results showed easterly winds as a significant predictor of P. noctiluca strandings. The bell diameters of examined jellyfish ranged from 30 to 130 mm, with mean of 72 mm. Stranded mature jellyfish individuals as well as young ones were recorded throughout the year 2018. The size distribution indicated that P. noctiluca can reproduce all around the year, with its more intense activityduring the spring. The continuing presence of P. noctiluca in the Moroccan Mediterranean makes it necessary to set effective strategies in order to prevent and minimize their impact on economic activities.
Two-dimensional arrangement of octadecylamine-functionalized gold nanoparticles using the LB technique

The LB technique is an important way to obtain the ordered aggregate of nanometre-sized particles. However, with the usual LB technique only those particles capped by short-chain molecules (<C12) can form a highly ordered two-dimensional (2D) arrangement. When the capping molecules become longer, it is difficult to obtain ordered aggregates. This has been considered to be caused by the hydrophobic interaction of the large organic shells, which has possibly hindered the procedure of self-assembly. Motivated by this, we modified the LB technique by using the multistep creeping method and increasing the subphase temperature during compression. With these modifications, we obtained the long-range ordered 2D arrangement of gold nanoparticles capped by octadecylamine.
Midterm Prognosis and Surgical Implication of Clival Chordoma after an Extended Transsphenoidal Tumor Removal and Gamma Knife Radiosurgery

Background: Treatment for chordoma by surgery alone is often ineffective, so surgery and irradiation is often performed with a reported 5-year survival rate of 60-75%. The clinical course varies; however, disease rarity has prevented large number clinical investigations. Methods: Nineteen patients suffering from clival chordomas were retrospectively investigated. They were initially treated with maximal tumor removals by extended transsphenoidal approach. When total removal was achieved prophylactic irradiation was not performed. If tumor remnants or recurrence was confirmed, gamma knife (GK) was performed. Follow-up periods ranged from 9 to 224 months (mean 85.4 months). Results: Total removal was achieved in 10 patients; however, 4 patients suffered recurrence and required GK. Overall progression free intervals were 9 to 151 months (mean 59.9 mzonths). GK was applied for 11 patients with a 50 % isodose of 13 to 18 Gy (mean 15.4 Gy). Eight patients remained progression free, but 3 patients suffered repeated local recurrence and died from tumor related complications. Overall survival was 9 to 224 months (mean 90.9 months). Eighteen patients survived more than 5 years with the exception of one male patient, who died of lung cancer 36 months after the initial treatment (5-year survival rate 94.7 %). The results indicated that sex (males), those given more than 15 Gy of a 50% isodose by GK, and prophylactic brain scanning were significant favorable prognostic factors. Conclusions: The favorable outcomes in this investigation may indicate value for early detection and early treatment. The role of surgery may be adequate conditioning for enough dose of GK.
Noncontact laser vibrometry-based fence-like arrays with wavefield filtering-assisted adaptive imaging algorithms for detecting multiple pits in a compact cluster

Pitting corrosion presents challenges for ultrasonic nondestructive evaluation due to the small pit dimension. Few Lamb wave-based techniques have achieved the identification of individual pits as subwavelength wave scatterers that are densely packed in a small cluster. In this article, noncontact laser vibrometry-based fence-like arrays with wavefield filtering-assisted adaptive imaging algorithms are developed for detecting and identifying small pits in a cluster. Signals of back scattering waves induced by a cluster of subwavelength scatterers are acquired by noncontact laser Doppler vibrometry at sensing points and form a fence-like array surrounding the area of inspection. The signals are then processed by our array imaging algorithms to construct inspection images which take advantage of three techniques, including the wave mode and wave direction filters to extract single-mode back scattering Lamb waves induced by subwavelength scatterers, the pseudo-reversal propagation of back scattering waves to address the dispersion effect and improve the radial imaging resolution, and the adaptive weighting to improve the angular imaging resolution. Moreover, this work introduces the wave diffraction-related Rayleigh and Abbe limits that are conventionally used for characterizing optic lenses, for characterizing the resolution limit of Lamb wave-based arrays, and optimizing the array configuration. To validate our array imaging approach, a proof-of-concept experiment has been performed to detect a cluster of 3 × 3 pits with the pit diameter of 2 mm and the interval of 2 mm in a 3.2-mm thick aluminum plate; the experimental imaging result shows that our method can identify most pits except the one at the center of the pit cluster. We believe this study will benefit the design, characterization, and optimization of Lamb wave-based arrays for subwavelength resolution imaging and enable potential applications for the noncontact inspection of hidden pitting corrosion in civil, petrochemical, nuclear, and aerospace structures.
Polymorphisms of human papillomavirus type 16 E7 in Uyghur women with cervical cancer

Purpose: To analyse the association of HPVl6 E7mutations with cervical cancer among Uyghur women in Xinjiang, China. Methods: From December 2008 to August 2010, 80 Uygur women who were confirmed to have cervical cancer were recruited. Cervical tissues were collected. DNA was extracted from the samples. HPVl6 L1 was amplified for the identification of tissues infected with HPV16. Polymerase chain reactions and DNA sequencing were then performed for polymorphism analysis of HPVl6 E7 in HPV16-infected tissues. Results: A total of 60 samples were confirmed to have HPV16 infection. Among these samples, 54 successfully underwent HPV16 E7 sequencing, and 6 were observed with E7 mutations. The locations of the mutations were A647G (2/54), T760C (2/54), G663A (1/54), G666A (1/54), C790T (1/54), and T846C (1/54). A647G (2/54) and C790T (1/54) were missense mutations. Conclusion: HPV16 E7 is conserved in Xinjiang with a relatively low mutation rate.
The Relationship between Haemoglobin Levels and Platelet Counts of Malaria Infected and Non-Infected Children in Offinso, Ghana

Malaria is known to have significant effects on the body. This study, investigated the relation between platelet and haemoglobin levels of malaria positive and negative children (age range = 1-14 years). Out of the 1049 children (4.1± 3.3 years), comprising 493 females and 556 males who were tested for malaria parasites, the prevalence of malaria was 35.3%. Children aged one year with malaria recorded the least hemoglobin concentration of 8.0 ± 2.4g/dL. As the age of the children with malaria infection increase, the haemoglobin concentration also increased. The prevalence of anemia (<10 g/dL) in malaria infected children was 55.4% compared to 28.0% in children without malaria. Children with malaria infection were up to 4.0 (OR) times more likely to have severe anemia (<7 g/dL) than those uninfected. Furthermore, only 5.6% of malaria negative patients had thrombocytopenia (platelet <150 ); while 49.5% of malaria positive children had thrombocytopenia. There was a significant weak positive correlation (rho=0.277) between haemoglobin and platelet count of malaria positive children, but a weaker negative correlation (r = -0.088) in those without malaria. The haemoglobin levels and platelet counts of children without malaria followed the normal distribution, while those with malaria did not. Therefore, haemoglobin and platelet data from malaria negative and positive children should be analysed differently to improve diagnosis and treatment.
Head-fake perception in basketball: the relative contributions of expertise, visual or motor training, and test repetition

ABSTRACT The present study was conducted to disentangle the relative impact of visual and motor experience on the processing of the head fake in basketball. In a pre-test-intervention-post-test study, we investigated if the head-fake effect can be reduced with either a one-week visual-training intervention (visual-training group: N = 17, 10 females, 7 males, mean age = 21.2 years) or with a one-week motor-training intervention (motor-training group: N = 17, 10 females, 7 males, mean age = 20.9 years). Additionally, a waiting-control group (N = 17, 8 females, 9 males, mean age = 23.1 years) without any intervention and a group of experienced basketball players (N = 21, 9 females, 12 males, mean age = 23.9) was tested in the pre-post-test design (i.e., without intervention). The size of the head-fake effect was measured in a laboratory setting with a reaction time experiment, in which participants had to classify the pass direction of a faking or non-faking basketball player, who was shown in a video on a screen wall. The study revealed that the head-fake effect decreased after the training interventions. Surprisingly, the waiting-control group showed similar improvements. Thus, the reduced head-fake effect appears to be based on test-repetition effects. Moreover, after a single test session the head-fake effect approached a level that experts displayed from the outset. Even a small amount of practice (i.e., test-repetition) is sufficient to reduce, though not to abolish, the head-fake effect. We discuss this finding with regard to the common-coding approach and working memory capacity.
Potential self-medication by brown titi monkeys, Plecturocebus brunneus, in an urban fragment forest in the Brazilian Amazon

Abstract In this study, we report fur-rubbing behavior of brown titi monkeys, Plecturocebus brunneus, using chewed leaves from (Fabaceae) and Piper tuberculatum (Piperaceae). These reports were obtained during systematic monitoring of titi monkeys from May until December 2019 (218 h) in an urban fragment forest in the Brazilian Amazon. Both plant species contain chemical substances in their leaves that potentially repel ectoparasites. The genus Piper is known for its repelling action due to the presence of amides, alkaloids and benzoic acid. The presence of dogs, cats and human settlements may contribute to an increase of ectoparasites, making a potential self-medication function of fur rubbing in this primate species plausible.
Investigation of the target-site resistance of EPSP synthase mutants P106T and T102I/P106S against glyphosate

The shikimate pathway enzyme 5-enolpyruvyl shikimate-3-phosphate synthase (EPSPS) catalyzes the reaction involved in the production of amino acids essential for plant growth and survival. Thus, EPSPS is the main target of various herbicides, including glyphosate, a broad-spectrum herbicide that acts as a competitive inhibitor of phosphoenolpyruvate (PEP), which is the natural substrate of EPSPS. However, punctual mutations in the EPSPS gene have led to glyphosate resistance in some plants. Here, we investigated the mechanism of EPSPS resistance to glyphosate in mutants of two weed species, Conyza sumatrensis (mutant, P106T) and Eleusine indica (mutant, T102I/P106S), both of which have an economic impact on industrial crops. Molecular dynamics (MD) simulations and binding free energy calculations revealed the influence of the mutations on the affinity of glyphosate in the PEP-binding site. The amino acid residues of the EPSPS protein in both species involved in glyphosate resistance were elucidated as well as other residues that could be useful for protein engineering. In addition, during MD simulations, we identified conformational changes in glyphosate when complexed with resistant EPSPS, related to loss of herbicide activity and binding affinity. Our computational findings are consistent with previous experimental results and clarify the inhibitory activity of glyphosate as well as the structural target-site resistance of EPSPS against glyphosate.
B. PENGARUH PERTUMBUHAN EKONOMI DAN KEMISKINAN TERHADAP INDEKS PEMBANGUNAN MANUSIA PROVINSI JAWA TIMUR 2008-2019

ABSTRAK Penelitian ini bertujuan untuk mengetahui pengaruh antara Pertumbuhan Ekonomi dan Kemiskinan terhadap Indeks Pembangunan Manusia di Provinsi Jawa Timur dalam kurun waktu 2008-2019. Metode yang digunakan dalam penelitian ini yaitu metode kuantitatif. Data yang digunakan merupakan data sekunder yang diperoleh dari Badan Pusat Statistik (BPS) Jawa Timur tahun 2008-2019. Penelitian ini menggunakan metode analisis data regresi linier berganda dan menggunakan uji BLUE. Alat bantu olah data yang digunakan yaitu SPSS 13.0 for windows. Dari hasil penelitian dapat disimpulkan bahwa: 1) Pertumbuhan Ekonomi berpengaruh positif dan signifikan terhadap IPM di Provinsi Jawa Timur. 2) Kemiskinan tidak berpengaruh terhadap IPM di Provinsi Jawa Timur. Kata kunci : pertumbuhan ekonomi, kemiskinan, indeks pembangunan manusia, regresi linier berganda ABSTRACT This study aims to determine the effect of economic growth and poverty on the Human Development Index in East Java Province in the period 2008-2019. The method used in this research is quantitative method. The data used is secondary data obtained from the East Java Central Statistics Agency 2008-2019. This study uses multiple linear regression data analysis methods and uses the BLUE test. The data processing tool used is SPSS 13.0 for windows. From the research results it can be concluded that: 1) Economic growth has a positive and significant effect on HDI in East Java Province. 2) Poverty has no effect on HDI in East Java Province. Key words: economic growth, poverty, human development index, multiple linear regression
Comparison of Ocular Biometry Profiles in Urban and Rural Cataract Candidates in Eastern China

Purpose To compare ocular biometric parameters between urban and rural cataract patients in Shanghai, China. Methods A study of ocular biometry records from urban and rural hospitals was performed for cataract patients at least 50 years of age. The ocular biometrical parameters, which were measured with partial coherence laser interferometry (IOL Master, Zeiss), were axial length (AL), anterior chamber depth (ACD), radius of corneal curvature (K, including steep/flat/average K), astigmatism, and axis. Only the right eye record of each patient was analysed. Results Ocular biometric data included 2839 urban patients (73.15 ± 9.54 years) and 2646 rural patients (73.64 ± 7.32 years). Mean AL, ACD, and K were 24.35 ± 2.34 mm, 3.14 ± 0.58 mm, and 44.38 ± 1.52 D, respectively, in urban patients and 23.58 ± 1.70 mm, 3.08 ± 0.57 mm, and 44.53 ± 1.50 D, respectively, in rural patients. The urban subjects had significantly longer axial lengths (in both univariate and multivariate linear regression analyses) and deeper ACDs (in univariate analysis) than rural subjects (p < 0.01). There was no significant difference in steep K, flat K, and average K between the two groups. With-the-rule (WTR) corneal astigmatism was found in 1787 eyes (32.58%), against-the-rule (ATR) corneal astigmatism was found in 2727 eyes (49.72%), and oblique corneal astigmatism was found in 971 eyes (17.70%). Conclusions We report biometry and astigmatism data in a large cohort of urban and rural adult subjects for the first time. In our study, a short AL, shallow ACD, and axis turned in an ATR direction had higher prevalence rates in the rural subjects. This profile of ocular biometric data and corneal astigmatism will be helpful in planning for intraocular lens (IOL) power calculations and astigmatism correction in subjects in different locations.
Adolescent Identity at School: Student Self-Positioning in Narratives concerning Their Everyday School Experiences

Abstract Identity, as a common way of thinking about ourselves and experiencing ourselves, begins to be explored and stabilized during adolescence. According to the narrative psychology, identity development occurs through self-positioning and the simultaneous positioning by others, within the discursive positions available in the present context, one of which is the school environment. The aim of our study was to explore student self-positioning in the narrated accounts of their everyday school experiences. The participants were primary school students that provided us with written accounts that represented their view of the school and of themselves. Data were analyzed in line with the principles of narrative and positioning analysis, which resulted in emergence of four types of events/experiences student accounted for: academic achievement and discipline, peer relationships, relationships with teachers and general school experience. Within these themes we further identified subthemes, the prevailing emotional tone and student self-positioning. Our findings suggest that positioning as a valuable and accepted friend was the prevailing one. We identified peer conflicts as the potential space for the further exploration of identities, and the position of the rejected student as a particularly restricting one. Interventions proposed include altering the structure of the positioning network by widening the space of accessible positions and altering its dynamic properties, so that mutual exclusiveness of some positions is removed.
What is the optimal number of neoadjuvant chemotherapy cycles for resectable colorectal liver oligometastases?

Background The optimal number of neoadjuvant chemotherapy (NAC) cycles for resectable colorectal liver oligometastases (CLOM) remains unclear. The aim of this study was to investigate the optimal number of NAC cycles. Methods One hundred twenty-nine consecutive patients were included in this study. X-tile analysis was implemented to investigate the optimal cut-off point for NAC cycles. Propensity score matching was performed to reduce selection bias. Kaplan-Meier curves and Cox risk regression models were used to analyse progression-free survival (PFS) and overall survival (OS). Results The optimal cut-off point for NAC cycles was 5. There were no significant differences in R0 resection, pathological response or postoperative complications between the groups with a low number of NAC cycles group (≤5 cycles, n=80) and high number of NAC cycles (>5 cycles, n=49). Patients with a high number of NAC cycles were more likely to have NAC toxicity than those with a low number of cycles (87.8% vs. 65.0%, P=0.004). Multivariate analysis revealed that >5 NAC cycles was an independent predictor of reduced PFS (HR =1.808, 95% CI: 1.205–2.712, P=0.004) and reduced OS (HR =1.723, 95% CI: 1.041–2.851, P=0.034). In the oxaliplatin-based regimen group, patients with a low number of NAC cycles had a better PFS (P<0.001, mPFS: 14.7 vs. 5.4 months) and better OS (P=0.018, mOS: 57.7 months vs. 41.0 months) than those with a high number of cycles. After 1:1 propensity matching (34 cases vs. 34 cases), multivariate analysis revealed that >5 NAC cycles was an independent predictor of reduced PFS (HR =2.265, 95% CI: 1.281–4.007, P=0.005) and reduced OS (HR =2.813, 95% CI: 1.359–5.822, P=0.005). In the oxaliplatin-based regimen group, patients with a low number of NAC cycles had better PFS (P<0.001, mPFS: 17.5 vs. 5.6 months) and better OS (P=0.008, mOS: 59.0 vs. 31.8 months) than those with a high number of cycles. Conclusions Fewer than 5 NAC cycles was optimal for biologically resectable CLOM patients. Giving more than 5 NAC cycles was unnecessary because a higher number of NAC cycles has more unfavourable survival and higher NAC toxicities, while leading to similar R0 resection rates and pathological responses.
Personal and Political: Post‐Traumatic Stress Through the Lens of Social Identity, Power, and Politics

Post‐traumatic stress disorder (PTSD) has always been controversial and highly politicized. Here, using a social identity approach, we review evidence that trauma and its aftermath are fundamentally linked to social position, sociopolitical capital, and power. We begin this contribution by demonstrating how a person's group memberships (and the social identities they derive from these memberships) are inherently linked to the experience of adversity. We then go on to consider how it is through group memberships that individuals are defined by their trauma risk and trauma histories—that is, a person's group memberships and their trauma are often inherently linked. Considering the importance of group memberships for understanding trauma, we argue that it is important to see these, and group processes more generally, as more than just “demographic” risk factors. Instead, we argue that when groups are defined by their trauma history or risk, their members will often derive some sense of self from this trauma. For this reason, attributes of group memberships are important in developing an understanding of adjustment and adaptation to trauma. In particular, groups' status, their recourse to justice, and the level of trust and solidarity within the group are all central to the impact of traumatic events on individual‐level psychological resilience. We review evidence that supports this analysis by focusing on the exacerbating effects of stigma and social mistrust on post‐traumatic stress, and the value of solidarity and strong identities for resilience. We conclude that because of these group‐related processes, trauma interweaves the personal with the political and that post‐traumatic stress is fundamentally about power, positionality, and politics.