Miracle-dz/UniFAR-FTUs huggingface dataset:
COMPARATIVE LOCAL GOVERNMENT RESPONSE TO COVID-19 IN DIFFERENT COUNTRIES: CASE IN GAMBIA AND INDONESIA

This study aims to evaluate the performance of two different local governments in two different nations using decentralization and policy implementation theories. It will also provide a general overview of the situation in these two nations at the time that Covid-19 began to spread. Using a comparative case study (CCS), this study compares local government response to Covid-19 in Gambia and Indonesia. In this study, the pandemic Covid-19 was given the same effect in each country but produced different results depending on government activities in each country. When the first Covid-19 cases appear in their countries, Gambia and Indonesia face a similar problem, but they also have a similar strategy for dealing with this pandemic outbreak. The Gambian government provides food, personal protective equipment (PPE), and essential sanitary items, as have several local governments in Indonesia. Gambia and Indonesia also establish a task force (both central and local government) to control virus spread, which becomes a key action in both countries' management of the Covid-19 outbreak. This research find that the role of local government in translating policy from the central government becomes critical to a region's success. A country's central government must not only maintain good performance in areas where it already excels, but also provide education and strong attention to local governments that are still struggling in order for them to improve their performance.
Numerical calculations of two-dimensional large Prandtl number convection in a box

Abstract Convection from an isolated heat source in a chamber has been previously studied numerically, experimentally and analytically. These have not covered long time spans for wide ranges of Rayleigh number Ra and Prandtl number Pr. Numerical calculations of constant viscosity convection partially fill the gap in the ranges $\mathit{Ra}= 1{0}^{3} {{\unicode{x2013}}}1{0}^{6} $ and $\mathit{Pr}= 1, 10, 100, 1000$ and $\infty $ . Calculations begin with cold fluid everywhere and localized hot temperature at the centre of the bottom of a square two-dimensional chamber. For $\mathit{Ra}\gt 20\hspace{0.167em} 000$ , temperature increases above the hot bottom and forms a rising plume head. The head has small internal recirculation and minor outward conduction of heat during ascent. The head approaches the top, flattens, splits and the two remnants are swept to the sidewalls and diffused away. The maximum velocity and the top centre heat flux climb to maxima during head ascent and then adjust toward constant values. Two steady cells are separated by a vertical thermal conduit. This sequence is followed for every value of $Pr$ number, although lower Pr convection lags in time. For $\mathit{Ra}\lt 20\hspace{0.167em} 000$ there is no plume head, and no streamfunction and heat flux maxima with time. For sufficiently large Ra and all values of Pr, an oscillation develops at roughly $t= 0. 2$ , with the two cells alternately strengthening and weakening. This changes to a steady flow with two unequal cells that at roughly $t= 0. 5$ develops a second oscillation.
Preparation and Characterization of Patch Loaded with Clarithromycin Nanovesicles for Transdermal Drug Delivery

Clarithromycin (CLR), categorized as a Biopharmaceutical Classification System class II drug, has several gastrointestinal tract side effects and an extremely unpalatable bitter taste. The current study aimed to design transdermal patch-embedded CLR niosomes to overcome the aforementioned CLR-related challenges. Various niosomal formulations were successfully fabricated and characterized for their morphology, size, in vitro release, and antimicrobial efficacy. Subsequently, the CLR niosomes were loaded into transdermal patches using the solvent casting method. The polydispersity index of the niosomes ranged from 0.005 to 0.360, indicating the uniformity of the niosomes. The encapsulating efficiency (EE)% varied from 12 to 86%. The optimal Chol: surfactant ratio for drug release was found to be 0.5:1. In addition, the encapsulation of CLR into niosomal nanovesicles did not reduce the antibacterial activity of the CLR. The niosomal patch had a significantly higher permeability coefficient of CLR than the conventional patch. In addition to that, a shear-thinning behavior was observed in the niosomal gels before loading them into a niosomal patch. The flux (Jss) of the niosomal patch was significantly higher than the conventional patch by more than 200 times. In conclusion, niosome-based transdermal patches could be a promising method for the transdermal drug delivery of class II drugs and drugs experiencing GIT side effects.
Review of Potential Barriers to Effective Hemostatic Management of Acquired Hemophilia A by Non-Hemophilia Experts in the United States

Acquired hemophilia A (AHA) is an ultra-rare autoimmune disorder caused by autoantibodies against factor VIII. It often presents with life-threatening bleeding to non-hemophilia experts, who have limited awareness of this condition. This review evaluated hemostatic management and identified barriers to optimal management of AHA by non-hemophilia experts in the United States through a literature review. AHA case reports published by non-hemophilia experts from January 2016 through November 2021 in non-hematology journals were critically reviewed for a chronology of clinical course and management, consultation with a hemophilia expert, referencing of available AHA recommendations, discussion of all hemostatic options, and bleed control outcomes; 24 case reports representing 24 patients were identified. Twelve patients had an apparent delay in diagnosis, 17 cases did not seek expert consultation, and 15 did not reference the 2009 International AHA Recommendations, including six in whom hemostatic treatment was not consistent with the recommendations. Of the 17 articles published after the 2017 AHA Guidance, eight did not reference them. Of the five articles published after the 2020 International Recommendations for AHA, three did not reference them. Overall, 14 articles did not discuss all available hemostatic treatment options. Four patients died. Our findings reveal variability in hemostatic management of AHA by non-hemophilia experts in the United States. Lack of AHA awareness remains a primary barrier for optimal management of AHA among non-hemophilia experts. Increasing education about existing AHA guidelines, including available therapies and access to expert care at hemophilia treatment centers, may help improve the outcomes of patients with AHA.
Preliminary Modeling of Magnetized Sprite Streamers on Jupiter Following Juno's Observations of Possible Transient Luminous Events

The first observation of possible transient luminous events (TLEs) on Jupiter was reported recently. Whereas initiation of elves on Jupiter has been theoretically studied before, the possibility of sprite streamer inception on Jupiter has not been investigated yet. Here we critically review the literature concerned with TLEs on Jupiter. Subsequently, we report on development of a numerical model for modeling of magnetized streamers in presence of Jupiter's strong magnetic field. The model utilizes the knowledge provided by recent observations of Jupiter's lightning and magnetic field by the Juno spacecraft. It is demonstrated that sprite streamer inception under realistic atmospheric conditions on Jupiter is possible.
The turbulent exponential jet

A new, self‐similar, turbulent jet flow is postulated in which the global vorticity Ω is a constant following any vortex. In contrast, conventional self‐similar flows all exhibit Ω inversely proportional to the vortex age. In order for the new, postulated flow to exist, the nozzle exit speed must increase exponentially with time. It is shown that this circumstance may strongly inhibit the entrainment of ambient fluid into the jet.
Quantifying the uncertainties of chemical evolution studies I. Stellar lifetimes and initial mass function

Stellar lifetimes and initial mass function are basic ingredients of chemical evolution models, for which different recipes can be found in the literature. In this paper, we quantify the effects on chemical evolution studies of the uncertainties in these two parameters. We concentrate on chemical evolution models for the Milky Way, because of the large number of good observational constraints. Such chemical evolution models have already ruled out significant temporal variations for the stellar initial mass function in our own Galaxy, with the exception perhaps of the very early phases of its evolution. Therefore, here we assume a Galactic initial mass function constant in time. Through an accurate comparison of model predictions for the Milky Way with carefully selected data sets, it is shown that specific prescriptions for the initial mass function in particular mass ranges should be rejected. As far as the stellar lifetimes are concerned, the major differences among existing prescriptions are found in the range of very low-mass stars. Because of this, the model predictions differ widely for those elements which are produced mostly by very long-lived objects, as for instance 3 He and 7 Li. However, we conclude that model predictions of several important observed quantities, constraining the plausible Galactic formation scenarios, are fairly robust with respect to changes in both the stellar mass spectrum and lifetimes. For instance, the metallicity distribution of low-mass stars is nearly unaffected by these changes, since its shape is dictated mostly by the time scale for thin-disk formation.
CHAOS GAME CHARACTERIZATION OF TEMPORAL PRECIPITATION VARIABILITY: APPLICATION TO REGIONALIZATION

We present an application of the fractal "chaos game representation" method in climatology for characterizing temporal precipitation aggregation patterns. To this aim, we establish an analogy with linguistic analysis considering precipitation as a discrete variable (e.g. rain, no rain). Each weekly, or monthly, symbolic sequence of observed precipitation is then considered a "word" and the climatological time series observed at a particular gauge defines a "language. " The distribution of different words within the language characterizes the particular precipitation aggregation scheme. In this paper we show that the chaos game representation method provides a graphical representation (a fractal pattern, or fingerprint) of the distribution of words and also gives a quantitative characterization in terms of parameters such as the box-counting dimension and the entropy. We show that different climates exhibit characteristic patterns with different fractal exponents and entropies. As an illustrative application, the method is used for automatic regionalization of a set of gauges in the Iberian peninsula, showing that these new indices outperform standard averaged statistics (monthly means, etc.).
Diagnostic and Prognostic Value of microRNAs in Patients with Laryngeal Cancer: A Systematic Review

Laryngeal squamous cell cancer (LSCC) is one of the most common malignant tumors of the head and neck region, with a poor survival rate (5-year overall survival 50–80%) as a consequence of an advanced-stage diagnosis and high recurrence rate. Tobacco smoking and alcohol abuse are the main risk factors of LSCC development. An early diagnosis of LSCC, a prompt detection of recurrence and a more precise monitoring of the efficacy of different treatment modalities are currently needed to reduce the mortality. Therefore, the identification of effective diagnostic and prognostic biomarkers for LSCC is crucial to guide disease management and improve clinical outcomes. In the past years, a dysregulated expression of small non-coding RNAs, including microRNAs (miRNAs), has been reported in many human cancers, including LSCC, and many miRNAs have been explored for their diagnostic and prognostic potential and proposed as biomarkers. We searched electronic databases for original papers that were focused on miRNAs and LSCC, using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) protocol. According to the outcome, 566 articles were initially screened, of which 177 studies were selected and included in the analysis. In this systematic review, we provide an overview of the current literature on the function and the potential diagnostic and prognostic role of tissue and circulating miRNAs in LSCC.
Explicit algebraic subgrid stress models with application to rotating channel flow

New explicit subgrid stress models are proposed involving the strain rate and rotation rate tensor, which can account for rotation in a natural way. The new models are based on the same methodology that leads to the explicit algebraic Reynolds stress model formulation for Reynolds-averaged Navier–Stokes simulations. One dynamic model and one non-dynamic model are proposed. The non-dynamic model represents a computationally efficient subgrid scale (SGS) stress model, whereas the dynamic model is the most accurate. The models are validated through large eddy simulations (LESs) of spanwise and streamwise rotating channel flow and are compared with the standard and dynamic Smagorinsky models. The proposed explicit dependence on the system rotation improves the description of the mean velocity profiles and the turbulent kinetic energy at high rotation rates. Comparison with the dynamic Smagorinsky model shows that not using the eddy-viscosity assumption improves the description of both the Reynolds stress anisotropy and the SGS stress anisotropy. LESs of rotating channel flow at Reτ = 950 have been carried out as well. These reveal some significant Reynolds number influences on the turbulence statistics. LESs of non-rotating turbulent channel flow at Reτ = 950 show that the new explicit model especially at coarse resolutions significantly better predicts the mean velocity, wall shear and Reynolds stresses than the dynamic Smagorinsky model, which is probably the result of a better prediction of the anisotropy of the subgrid dissipation.
Theoretical Upper Bound and Lower Bound for Integer Aperture Estimation Fail-Rate and Practical Implications

Integer ambiguity validation is pivotal in precise positioning with Global Navigation Satellite Systems (GNSS). Recent research has shown traditionally used ambiguity validation methods can be classified as members of the Integer Aperture (IA) estimators, and by the virtue of the IA estimation, a user controllable IA fail-rate is preferred. However, an appropriately chosen fail-rate is essential for ambiguity validation. In this paper, the upper bound and the lower bound for the IA fail-rate, which are extremely useful even at the designing stage of a GNSS positioning system, have been analysed, and numerical results imply that a meaningful IA fail-rate should be within this range.
Dust Accumulation Biases in PIRATA Shortwave Radiation Records

AbstractLong-term and direct measurements of surface shortwave radiation (SWR) have been recorded by the Prediction and Research Moored Array in the Tropical Atlantic (PIRATA) since 1997. Previous studies have shown that African dust, transported westward from the Sahara and Sahel regions, can accumulate on mooring SWR sensors in the high-dust region of the North Atlantic (8°–25°N, 20°–50°W), potentially leading to significant negative SWR biases. Here dust-accumulation biases are quantified for each PIRATA mooring using direct measurements from the moorings, combined with satellite and reanalysis datasets and statistical models. The SWR records from five locations in the high-dust region (8°, 12°, and 15°N along 38°W; 12° and 21°N along 23°W) are found to contain monthly-mean accumulation biases as large as −200 W m−2 and record-length mean biases on the order of −10 W m−2. The other 12 moorings, located mainly between 10°S and 4°N, are in regions of lower atmospheric dust concentration and do not show s.
Infinite Horizon Investment—Consumption Policies

We consider an infinite horizon investment-consumption problem in which the objective is to mmimize the discounted sum of the one period utilities. The one period utility function is assumed to be concave but may be unbounded. Both the state and action spaces are uncountable. If the average growth rate of assets is less than the reciprocal of the discount rate and if a weak regularity condition is satisfied an optimal stationary policy is shown to exist. Also the optimal return function satisfies the functional equation of dynamic programming and inherits several properties of the one period utility function.
Management of Brain Arteriovenous Malformations: A Review

Brain arteriovenous malformations (bAVM) are vascular malformations of the brain affecting all ages. The optimum management strategy is essentially devoid of high-quality evidence and is highly nuanced and embedded in local customs. This study summarizes the frequently employed management strategies, drawing conclusions on the utility of each method of treatment and delving into controversies surrounding them. A literature search on PubMed and Medline was done on January 3rd, 2022. 11,767 articles were found, and abstracts were reviewed. Full-text review of 153 articles led to chapters from three books and 71 articles incorporated into a summative discussion. Spetzler-Ponce (S-P) Class A patients may be offered surgery if they are good surgical candidates and have a good number of high-quality years of life left. The exception is diffuse Spetzler-Martin (S-M) grade 2 in a patient older than 40 years: radiosurgery for unruptured and embolization for ruptured. S-P Class B may be offered surgery if a compact nidus or if younger than 40 years. If diffuse or age greater than 40, radiosurgery may be preferred if the Pollock-Flickinger score is less than 2.5. For the remainder of S-P Class B, conservative management may be preferred. S-P Class C is generally not treated unless young or those patients with poorly controlled seizures affecting their quality of life are willing to risk permanent neurological deficits. While the quality of studies is generally high, the level of evidence is concerning with only one randomized controlled trial (RCT). Most research output hails from high-income countries, i.e., perhaps not universally applicable to all settings owing to possible genetic, environmental, and resource differences. More research is needed: large volume studies in the pregnant population, validation of scoring systems in pediatric age groups, clinical trials focused on combination multi-staged treatment modalities, and studies originating from the developing world.
Distortion of finite amplitude ultrasound in lossy media

A form of Burgers’ equation is used to derive an algorithm for calculating harmonic generation by a continuous plane wave of ultrasound propagating in a nonlinear, lossy, nondispersive medium. The algorithm accounts for attenuation that is not quadratically related to the frequency of the wave. Attenuation strongly affects the rate of harmonic production. The effect of variations of the relationship between attenuation and frequency is shown. Biological tissue is an example of a highly lossy medium where the attenuation does not increase with the square of the frequency. Calculations for several types of tissue and biological fluids are presented that show, for certain conditions, finite amplitude distortion is possible.
Stability of linear Markovian jump systems

The authors study the stability properties of linear Markovian jump systems and the relationship among second moment and sample path stability properties. It is shown that asymptotic mean square stability, exponential mean square stability, and stochastic stability are equivalent, and that they imply almost sure stability of the system. The relation between almost sure stability and delta -moment stability for ID jump linear systems is also examined. The Lyapunov exponent method for the study of almost sure stability is discussed, and a theorem which characterizes the qualitative properties of Lyapunov exponents of the jump linear systems is stated. <<ETX>>
GENERALIZED (α, β)*-DERIVATIONS AND RELATED MAPPINGS IN SEMIPRIME *-RINGS

Let R be a *-ring. Suppose α and β are the endomorphisms of R. In this paper we introduce the notions of generalized (α, β)*-derivation and symmetric generalized (α, β)*-biderivation. It is shown that if a semiprime *-ring admits a generalized (α, β)*-derivation F such that α is surjective then F maps the ring R into its center. Analogous results have been proved for symmetric generalized (α, β)*-biderivation.
Linear Regression Limit Theory for Nonstationary Panel Data

This paper develops a regression limit theory for nonstationary panel data with large numbers of cross section and time series observations. The limit theory allows for both sequential limits and joins limits, and the relationship between these multidimensional limits is explored. The panel structures considered allow for no time series cointegration, heterogeneous cointegration, homogeneous cointegration, and near-homogeneous cointegration. The paper explores the existence of long-run average relations between integrated panel vectors. In the case of homogeneous and near homogeneous cointegrating panels, a panel fully modified regression estimator is developed and studied.
Changes in Sleep Satisfaction of Korean Adolescents in the Pre- and Post-COVID-19 Eras and Its Effects on Health Behaviors

Adolescence is a crucial period for cognitive and psychological development and physical maturation. During this period, hormonally influenced circadian rhythms lead to reduced hours of sleep, and it is important to determine whether sleep quality is sufficient for fatigue relief. Non-face-to-face classes during coronavirus disease-2019 (COVID-19) potentially affected adolescents’ sleep quality, psychological state, amount of physical activity, smoking, alcohol consumption, and internet (smartphone) use. We investigated the effects of the COVID-19 situation on adolescents’ sleep satisfaction and its relation to the aforementioned factors. Data of 109,281 adolescents collected via an online survey, conducted from 3 June 2019 to 12 July 2019 and from 3 August 2020 to 13 November 2020, were analyzed. Health status comparison between the satisfactory and unsatisfactory sleep groups yielded significant results (odds ratio [OR] = 1.10, confidence interval [CI] = 1.04–1.17) for 2020. In both groups, perceived health was worse in 2019 than in 2020 (OR = 2.72, CI = 2.53–2.92). During COVID-19, non-face-to-face classes increased adolescents’ sleep satisfaction. Their psychological state improved, while amount of physical activity (muscle-strengthening exercises), average weight, and internet (smartphone) use increased. Smoking and alcohol consumption decreased.