Miracle-dz/UniFAR-FTUs huggingface dataset:
Lung Cancer Research in India and Iran: A Scientometric Study Lung Cancer Research in India and Iran: A Scientometric Study

The study aims to provide global research productivity on lung cancer with an in-depth analysis of the growth & development of India and Iran. The study focuses on the authorship collaborative patterns among Indian and Iranian medical scientists as well. The research started with the selection of terms on “Lung cancer”. Three terms- Lung Cancer, Lung Neoplasm, and Pulmonary Neoplasm were selected from the Medical Subject Headings (MeSH) to retrieve the data from the Web of Science (WoS). The Boolean Operator “OR” was executed to retrieve the records. The data related to Lung cancer research from 1989-2017 was retrieved and downloaded in the excel file after restricting the country to India and Iran. Later, Microsoft Excel , STATA, and EViews software were used to analyze the data. Three important means- annual growth rate (AGR), relative growth rate (RGR), and Doubling Time (DT) have been used to trace the development of literature from 1989 to 2017. Further, authorship patterns were analyzed using the authorship collaboration and collaborative coefficient methods. The findings of the study show that there is a strong and considerable relationship between the Gross Domestic Production (GDP) of nations and publication productivity. The annual growth rate is slow in the onset as compared to the later years, which is a positive sign of the improvement in the research productivity of India and Iran while as relative growth rate shows a decrease, doubling time shows an increasing trend in both nations towards the end of 2017. Authors prefer to work in collaboration rather than individually.
EFFECTS OF UREA - AMMONIATION AND COTTON SEED CAKE SUPPLEMENTATION ON THE UTILIZATION OF SORGHUM STOVER BY SHEEP

The effects cotton seed cake (CSC) supplementation and urea-ammoniation on utilization of sorghum stover by Yankasa sheep was studied. Chopped sorghum stover was ensiled with fertilizer grade urea at 4% urea (w/w), the urea being dissolved in water to reconstitute the silage to 50% DM. The experiment was a 2x3 factorial design of unammoniated and ammoniated sorghum stover and three levels of CSC supplementation (0.5, 1.0 and 1.5% of the sheep body weight). The growth trial was conducted with 24 yearling sheep, averaging 18.2 kg liveweight and lasted for 60 days. Intake of sorghum stover by sheep was Improved (P<0.05) by urea-ammoniation, not significant (P>0.05). Increasing the level of supplementation with CSC improved (P>0.05) stover intake by sheep fed the ammoniation of unammonlated stover, but resulted in decreased (P>0.05) intake of ammonlated by sheep. Sheep liveweight gains were improved by ammoniation and supplementation (P<0.01). The interaction between urea-ammoniation of stover and supplementation resulted in better (P<0.05) live weight going in sheep. Twelve Yankasa ruang averaging 16.9 kg liveweight were Ammoniation and supplementation did not affect DM, NDF and ADF digestibilities (P>.05), but resulted in increase (P<0.05) in cellulose and hemicellulose digestion. Ammoniation and supplementation resulted in N-balance of the sheep. Ammoniation resulted in marked Increases (P <0.01) in rumen ammonia concentrations, but increasing 50% DM. The material was epsiled above the level of supplementation did not appreciably(P<0.05) silled rumen ammonia concentrate
villout.chp:Corel VENTURA

In 1967, Ashbaugh et al (1) defined the acute respiratory distress syndrome (ARDS) in 12 adult patients. The patients were identified as having respiratory distress with tachypnea, hypoxemia, decreased respiratory system compliance and bilateral pulmonary infiltrates. The survival rate was 42%, and on pathology the nonsurvivors had heavy lungs, atelectasis, interstitial and alveolar edema, as well as hyaline membranes. Since that time, the hallmarks of this syndrome have included a risk factor for the development of ARDS; severe hypoxemia with a relatively high fraction of inspired oxygen (FiO2); decreased pulmonary compliance; and bilateral pulmonary infiltrates, in a setting in which cardiogenic pulmonary edema has been ruled out. Sepsis is the most common predisposing factor for the development of ARDS, accounting for approximately 35% to 50% of the mortality of ARDS. However, the major determinant of outMECHANICAL VENTILATION SYMPOSIUM
Toll-like receptor-2-activating bi¢dobacteria strains di¡erentially regulate in£ammatory cytokines in the porcine intestinal epithelial cell culture system: ¢nding new anti-in£ammatory immunobiotics

A total of 23 strains of biﬁdobacteria taxonomically belonging to ﬁve species were tested for their potent immunomodulatory effect using a combination of two methods: the NF- k B-reporter assay using a toll-like receptor 2-expressing transfectant (HEK pTLR2 system) and the mitogenic assay using porcine Peyer’s patches immunocompetent cells. Among the four preselected strains from different immunomodulatory groups, Biﬁdobacterium breve MCC-117 was able to efﬁciently modulate the inﬂammatory response triggered by enterotoxigenic Escherichia coli (ETEC) in a porcine intestinal epithelial (PIE) cell line. Moreover, using PIE cells and swine Peyer’s patches immunocompetent cell co-culture system, we demonstrated that the immunoregulatory effect of B. breve MCC-117 was related to the capacity of the strain to inﬂuence PIE and immune cell interactions, leading to the stimulation of regulatory T cells. The results suggested that biﬁdobacteria that express high activity in both the HEK pTLR2 and the mitogenic assays may behave like potential anti-inﬂammatory strains. The combination of the HEK pTLR2 system, the evaluation of mitogenic activity and PIE cells will be of value for the development of new immunologically functional foods and feeds that could prevent inﬂammatory intestinal disorders. Although our ﬁndings should be proven in appropriate experiments in vivo , the results of the present work provide a scientiﬁc rationale for the use of B. breve MCC-117 to prevent ETEC-induced intestinal inﬂammation. as
Preliminary study of the growth of Oreochromis niloticus var. Rocky Mountain and Lycopersicum esculentum L. cultured in aquaponic/Biofloc system

Aquaponic cultures control the residual nutrient accumulation that come from aquaculture activity, which reduces the fertilizer and water consumption without affecting culture demean quality and productivity. Twenty-five juvenile stage of Oreochromis niloticus var. Rocky Mountain juveniles with a mean total length of 6.15 to 6.55 cm and mean weight of 5.51 to 9.87 g were cultured in 200 L plastic beakers with 160 L of freshwater (0.80 x1.0 m). Tomato plants were sown in PVC tower aquaponic system. Every 15 days, total length of tomatoes stem and fishes were measured. Organisms with longest total length were those fed with Tilapia pellet with fertilized plants with 24.68±0.20 cm, meanwhile lowest values were for Tetracolor® without fertilized plants with 16.31±0.37 cm. The tallest stem was found with Tilapia pellet and fertilized plant with 271.56 ±0.48 cm and the smallest stem was for Tetracolor without fertilized plants with 192.03 ±0.26 cm. The results show a tilapia and tomato plant growth and weight increase in aquaponic/Biofloc integrated culture system.
Distance Learning in Forensic Nursing: The Lived Educational Experience

This phenomenological study was the first to understand nursing students’ lived experiences while taking a forensic nursing course in a distance learning format. Previous studies have shown the effectiveness of distance learning for reaching a wide variety of students in a changing academic landscape as well as individuals looking for educational options in an asynchronous setting. However, there was a deficit in the literature as it related to distance learning in forensic science fields. This study involved interviews with undergraduate and graduate nursing students at a large research university in the northeast United States. The three resulting themes were: asynchronous classes build motivation through independence, being confident in your support systems helps reduce online anxiety and learning in your own space improves focus. The findings in this study seem to support findings in similar studies focused on general nursing courses.
Human Atrial Fibrillation Drivers Correlated With Integrated Functional and Structural Imaging to Bene ﬁ t Clinical Mapping

OBJECTIVES This study sought to improve atrial ﬁ brillation (AF) driver identi ﬁ cation by integrating clinical multielectrode mapping with driver ﬁ ngerprints de ﬁ ned by high-resolution ex vivo 3-dimensional (3D) functional and structural imaging. BACKGROUND Clinical multielectrode mapping of AF drivers suffers from variable contact, signal processing, and structural complexity within the 3D human atrial wall, raising questions on the validity of such drivers. METHODS Sustained AF was mapped in coronary-perfused explanted human hearts (n ¼ 11) with transmural near-infrared optical mapping ( w 0.3 mm 2 resolution). Simultaneously, custom FIRMap catheters ( w 9 (cid:2) 9 mm 2 resolution) mapped endocardial and epicardial surfaces, which were analyzed by Focal Impulse and Rotor Mapping activation and Rotational Activity Pro ﬁ le (Abbot Labs, Chicago, Illinois). Functional maps were integrated with contrast-enhanced cardiac magnetic resonance imaging ( w 0.1 mm 3 resolution) analysis of 3D ﬁ brosis architecture. RESULTS During sustained AF, near-infrared optical mapping identi ﬁ ed 1 to 2 intramural, spatially stable re-entrant AF drivers
“Investigating happiness at work along the organizational life cycle: Moderating role of locus of control”

This study used business units in different stages of the organizational lifecycle (OLC) and tested employee job satisfaction, affective organizational commitment, and work engagement to understand the relationship between OLC and happiness at work. Furthermore, this study investigated Person-Organization (P-O) fit by testing for a locus of control (LOC) as a moderator to this relationship. Based on the significance of LOC for accountants, online surveys were launched in an accounting firm across twelve locations in South Africa. For the first survey, 32 partners (91%) positioned their business units onto specific stages of the OLC. In the second survey, employees (62%) completed self-evaluations of their level of job satisfaction, affective organiza- tional commitment, work engagement, and their LOC. Spearman’s rank-order correlations revealed the range of ρ of –1.22 at a 10% significance to –1.67 at a 5% significance, concluding earlier stages of OLC to support greater levels of happiness at work. Additionally, hierarchal regression found R-squared changes of 2% to 4%, confirming LOC as a moderator. Simulation tests found the strongest correlations with early stages of OLC for externals (range of ρ of –0.374 to –0.352 at 5% significance), moderate for internals (range of ρ of –2.12 at 10% significance to insignificant), and no relationship for those with a balanced expectancy (all insignificant). Contrary to dominant voices in the literature that support internality as a superior expectancy, this study concludes that those with a balanced LOC are more resilient to organizational factors for their happiness at work.
L IBERALIZATION AND S TOCK M ARKET C O M OVEMENT BETWEEN E MERGING M ARKETS

In this paper, we investigate the impact of trade and financial liberalization on the degree of stock market co-movement among emerging economies. Using a sample of 25 developing countries observed over 15 years, we estimate the impact of reforms which aim at opening these countries to trade and financial channels to the rest of the world. The estimation of time-varying cross-country correlations allows the econometric investigation to be performed using a panel data framework, raising hence the quality of the statistical inference. Our results offer strong support in favor of a positive impact of trade and financial liberalization reforms on the degree of cross-country stock market linkages.
Metagenomics of Antimicrobial Resistance in Gut Microbiome Metagenomics of Antimicrobial Resistance in Gut Microbiome

A healthy human body functions in sync with a wide array of gut microbes collectively known as human gut microbiome. They complement in a number of functions which are essential in our daily life such as in food metabolism. Various illnesses including colon cancer, autism, obesity, and autoimmune diseases have been linked to an imbalanced gut microbiota. Antibiotics are indispensable drug; however, the administration of antibiotics in humans as well as in animal farms has shown to increase antimicrobial resistance genes (ARGs) in gut microbiome. This is of serious concern since the commensals in gut microbiome could capture ARGs through horizontal gene transfer which in turn could cause postsurgical infections. In addition, numerous studies have consistently shown that the gut microbiome is unique to each individual. Hence, in-depth knowledge on the gut microbiota community and the factor responsible for shaping and spreading of ARGs is essential. This would in turn enable the development of custom-tailored personalized food and drugs in the future.
Fe / Mg-Modiﬁed Carbonate Apatite with Uniform Particle Size and Unique Transport Protein-Related Protein Corona E ﬃ ciently Delivers Doxorubicin into Breast Cancer Cells

: Breast cancer is the abnormal, uncontrollable proliferation of cells in the breast. Conventional treatment modalities like chemotherapy induce deteriorating of DOX in acidic pH. Enhancement of cytotoxicity for the chemotherapy drug was greater for Fe / Mg-CA NPs as compared to CA NPs, which could be explained by an increase in cellular internalization as a result of the small z-average diameter of the former. The protein corona study by LCMS demonstrated that Fe / Mg-CA NPs exhibited the highest a ﬃ nity towards transport proteins without binding with opsonins. Biodistribution study was performed to study the e ﬀ ect of DOX-loaded Fe / Mg-CA NPs on the tissue distribution of DOX in Balb / c 4T1 tumor-bearing mice. Both formulations of Fe / Mg-CA NPs have signiﬁcantly increased the accumulation of DOX in tumors. Interestingly, high Fe / Mg-CA NPs exhibited less o ﬀ -target distribution compared to low Fe / Mg-CA NPs. Furthermore, the blood plasma analysis revealed prolonged blood circulation half-life of DOX-loaded low and high Fe / Mg-CA NPs compared to free DOX solution. Modifying CA NPs with Fe 3 + and Mg 2 + , thereby, led to the generation of nano-sized particles with less tendency to aggregate, enhancing the drug binding e ﬃ ciency, cellular uptake, and cytotoxicity without hampering drug release in acidic pH, while improving the circulation half-life and tumor accumulation of DOX. Therefore, Fe / Mg-CA which predominantly forms a transport protein-related protein corona could be a proﬁcient carrier for therapeutic delivery in breast cancer.
Novi i za viktimološku teoriju i praksu

T he focus of the paper is on domestic violence against immigrant women during the transit and stay in Serbia, on their way from MENA countries 1 to the European Union. The objective is to present and analyze the phenomenon. It is contextualized within a theoretical framework of intersections between domestic violence, migration and the crisis and consideration of migration from MENA countries flowing through Serbia, as a part of the Western Balkan’s Route, with an emphasis on immigrant women. This is followed by the scrutinisation of domestic violence against immigrant women in Serbia – its occurrence and reporting, along with the author’s reflections thereof. Main conclusions point to the importance of preventive and empowering strategies directed towards immigrant women. Challenges to that are numerous: some stem from under­ performance of services aimed at prevention and empowerment of women who are victims of domestic violence in Serbia in general, and some are related to the factors specific for the situation of immigrant women.
Title: Phenotypic plasticity and genetic adaptation of functional traits influences intraspecific variation in hydraulic efficiency and safety

: Understanding which hydraulic traits are under genetic control and/or are phenotypically plastic is essential in understanding how tree species will respond to rapid shifts in climate. We quantified hydraulic traits in Eucalyptus obliqua across a precipitation gradient in the field to describe: 1) trait variation in relation to long-term climate and 2) the short-term (seasonal) ability of traits to adjust (i.e., phenotypic plasticity). Seedlings from each field population were raised under controlled conditions to assess: 3) which traits are under strong genetic control. In the field, drier populations had smaller leaves with anatomically thicker xylem vessel walls, a lower leaf hydraulic vulnerability and a lower water potential at turgor loss point, which likely confers higher hydraulic safety. Traits such as the water potential at turgor loss point and ratio of sapwood to leaf area (Huber Value) showed significant adjustment from wet to dry conditions in the field, indicating phenotypic plasticity and importantly, the ability to increase hydraulic safety in the short-term. In the nursery, seedlings from drier populations had smaller leaves and a lower leaf hydraulic vulnerability, suggesting key traits associated with hydraulic safety are under strong genetic control. Overall, our study suggests that strong genetic control over traits associated with hydraulic safety, which may compromise the survival of wet-origin populations in drier future climates. However, phenotypic plasticity in physiological and morphological traits may confer sufficient hydraulic safety to facilitate genetic adaptation.
Post Dural Puncture Headache (PDPH) and Associated Factors after Spinal Anesthesia among Patients in University of Gondar Referral and Teaching Hospital,

Background: Post dural puncture headache (PDPH) has been a problem for patients after dural puncture. It is one of the most frequently occurring complications following spinal anesthesia (SA). It is believed to originate from persistent leakage of cerebrospinal fluid (CSF) through the punctured Dura, greater than the CSF production after lumbar puncture. Although the problem has been widely reported, its magnitude and associated factors has never been studied in our country. Thus, the aim of this study is to assess the magnitude of post dural puncture headache (PDPH) and associated factors after spinal anesthesia among patients in university of Gondar referral and teaching hospital. Methods: An institution based cross sectional study was conducted from February 25-April 10, 2013 in University of Gondar teaching and referral hospital, Gondar, Ethiopia. A total of 116 patients aged 17-74 years were included in the study. Data was collected by interviewing patients using structured and pre-tested questionnaire and reviewing chart. Both bivariable and multivariable logistic regressions were used to determine the association between post dural puncture headache and independent variables. Results: Out of 116 patients who have undergone spinal anesthesia 45 (38.8%) patients developed post dural puncture headache. Sex [AOR=0.2; 95% CI: 0.058, 0.67], repeated attempts [AOR=0.22; 95% CI: 0.09, 0.54], and needle sizes [AOR=5.3; 95% CI: 1.66, 16.93] were found to be significantly associated with Post Dural puncture headache. Conclusion: Prevalence of post dural puncture headache was found to be high among patients in the University of Gondar teaching and referral hospital after spinal anesthesia (SA). The hospital management and the anesthetists of University of Gondar teaching and referal hospital should minimize the incidence of post dural puncture headache by avoiding use of big needles and repeated attempt especially on female patients.
U NCOVERING THE IMPACT OF HYPERPARAMETERS FOR GLOBAL MAGNITUDE PRUNING

A common paradigm in model pruning is to train a model, prune, and then either fine-tune or, in the lottery ticket framework, reinitialize and retrain. Prior work has implicitly assumed that the best training configuration for model evaluation is also the best configuration for mask discovery. However, what if a training configuration which yields worse performance actually yields a mask which trains to higher performance? To test this, we decoupled the hyperparameters for mask discovery (Hfind) and mask evaluation (Heval). Using unstructured magnitude pruning on vision classification tasks, we discovered the “decoupled find-eval phenomenon,” in which certain Hfind values lead to models which have lower performance, but generate masks with substantially higher eventual performance compared to using the same hyperparameters for both stages. We show that this phenomenon holds across a number of models, datasets, configurations, and also for one-shot structured pruning. Finally, we demonstrate that different Hfind values yield masks with materially different layerwise pruning ratios and that the decoupled find-eval phenomenon is causally mediated by these ratios. Our results demonstrate the practical utility of decoupling hyperparameters and provide clear insights into the mechanisms underlying this counterintuitive effect.
LETM1-dependent mitochondrial Ca 2 (cid:2) ﬂux modulates cellular bioenergetics and proliferation

Dysregulation of mitochondrial Ca 2 (cid:2) -de-pendent bioenergetics has been implicated in various pathophysiological settings, including neurodegenera-tion and myocardial infarction. Although mitochondrial Ca 2 (cid:2) transport has been characterized, and several molecules, including LETM1, have been identiﬁed, the functional role of LETM1-mediated Ca 2 (cid:2) transport remains unresolved. This study examines LETM1-me-diated mitochondrial Ca 2 (cid:2) transport and bioenergetics in multiple cell types, including ﬁbroblasts derived from patients with Wolf-Hirschhorn syndrome (WHS). The results show that both mitochondrial Ca 2 (cid:2) inﬂux and efﬂux rates are impaired in LETM1 knockdown, and similar phenotypes were observed in (cid:3) EF hand, D676A LETM1 mutant-overexpressed cells, and in cells derived from patients with WHS. Although LETM1 levels were lower in WHS-derived ﬁbroblasts, the mitochondrial up-
Disc-jet coupling in the 2009 outburst of the black hole candidate H 1743-322

We present an intensive radio and X-ray monitoring campaign on the 2009 outburst of the Galactic black hole candidate X-ray binary H1743-322. With the high angular resolution of the Very Long Baseline Array, we resolve the jet ejection event and measure the proper motions of the jet ejecta relative to the position of the compact core jets detected at the beginning of the outburst. This allows us to accurately couple the moment when the jet ejection event occurred with X-ray spectral and timing signatures. We find that X-ray timing signatures are the best diagnostic of the jet ejection event in this outburst, which occurred as the X-ray variability began to decrease and the Type C quasi-periodic oscillations disappeared from the X-ray power density spectrum. However, this sequence of events does not appear to be replicated in all black hole X-ray binary outbursts, even within an individual source. In our observations of H1743-322, the ejection was contemporaneous with a quenching of the radio emission, prior to the start of the major radio flare. This contradicts previous assumptions that the onset of the radio flare marks the moment of ejection. The jet speed appears to vary between outbursts, with a possible positive correlation with outburst luminosity. The compact core radio jet reactivated on transition to the hard intermediate state at the end of the outburst, and not when the source reached the low hard spectral state. Comparison with the known near-infrared behaviour of the compact jets suggests a gradual evolution of the compact jet power over a few days near the beginning and end of an outburst.