Miracle-dz/UniFAR-FTUs huggingface dataset:
Pathological Diagnostic Efficacy and Influencing Factors of Ovarian Tumour Using Cytological Smears Combined with Frozen Sections

The objective of this study was to investigate the pathological diagnostic efficacy of applying cytological smears (CytS) combined with frozen sections (FroS) in patients with ovarian tumour (OT), and to study the relevant factors affecting the pathological diagnostic efficacy of CytS combined with FroS. A total of 106 patients admitted for OT surgery from May 2022 to May 2023 were selected as study subjects using simple random sampling method. FroS, CytS and paraffin sections were performed on all tumour tissue specimens during and after surgery. In the univariate analysis, tumour diameter and whether metastasis was a relevant factor affecting the diagnostic efficacy of cytology smear combined with frozen section, and in the multivariate logistic regression analysis, tumour diameter and whether metastasis was an independent risk factor affecting the pathological diagnostic efficacy of cytology smear combined with frozen section. The application value of cytology smear combined with frozen section diagnosis in OT patients is high, and its diagnostic effect is good. In order to ensure the accuracy of the diagnostic results of cytology smear combined with frozen section diagnostic results, the size of the diameter of the patient’s tumour and whether metastasis occurs should be taken into account during the actual test, so as to improve the diagnostic accuracy of the case and provide a strong basis for clinical treatment.
Beyond Main Effects? Affect Level as a Moderator in the Relation Between Affect Dynamics and Depressive Symptoms

The current study examined the role of mean levels of affect in the relation between affect dynamics and depressive symptoms. We analyzed data from seven studies that measured affect in daily life in adolescents and young adults (N = 1,448, age range = 11.7-29.9 years, 64.8% females). We tested main and interaction effects of affect dynamics (variability and inertia) and affect level on depressive symptoms, separately for positive affect (PA) and negative affect (NA). For PA, we found mostly main, but no interaction effects. Depressive symptoms were associated with more PA variability and less PA inertia, indicating that depressive symptoms in young people may be characterized by more variable and less lingering PA, independent of PA mean levels. For NA, we found a significant moderation effect between NA variability and NA levels for depressive symptoms at baseline. For individuals with low NA levels, high NA variability was associated with more depressive symptoms. In contrast, for individuals with high NA levels, high NA variability was associated with fewer depressive symptoms. These results suggest that the relative adaptiveness of NA variability depends on overall NA levels and underscores the need for a more nuanced understanding of affect variability in depression.
The Haua Fteah, Cyrenaica (Northeast Libya): renewed investigations of the cave and its landscape, 2007

Abstract The 1950s excavations by Charles McBurney in the great Haua Fteah cave in northeast Libya revealed a deep (14 m) sequence of human occupation going back at least 100,000 years, with evidence for the presence of both Neanderthals and Modern Humans in the Pleistocene, and for Neolithic farmers in the Holocene. In 2007 a renewed programme of archaeological and geomorphological investigation began with the objective of improving understanding of the cave's occupation sequence and, combined with fieldwork in the landscape, of the history of landscape change and human responses to it. The initial season of fieldwork removed the upper c. 4.5 m of backfill in the McBurney trench; established the robustness of the original faces and their suitability for analytical interventions; recorded detailed running sections spanning from the present day to (at least) the Last Glacial Maximum c. 20,000 years ago; and indicated the potential of the surviving archaeology to reveal not just sequence but also activities or ‘taskscapes’ at the site. The geomorphological fieldwork identified rich sequences of later Quaternary deposits (marine, colluvial, alluvial, aeolian) with the potential to provide significant results regarding the history of climate and environment in the region. Archaeological survey around the cave indicates that the variability of the surface lithic evidence appears to reflect real differences in past human behaviour and use of the landscape and not just post-depositional taphonomic processes. Fifty years after the extraordinary pioneering work of McBurney and his colleagues, the new work demonstrates the continued potential of the Haua Fteah's unique occupation sequence and the multi-period ‘human landscapes’ around it to transform understanding of early human societies in North Africa.
The Percentage of Depressive Symptoms in Patients with Type 2 Diabetes Mellitus in M Djamil General Hospital Padang, Indonesia

The objectives of this study are to find the percentage of depressive symptoms and the most appeared clinical manifestation of depressive symptoms. A total of 2016 patient with type 2 diabetes from M Djamil General Hospital had fulfilled the questionnaire we administered. Demographic and clinical data were determined from the patient’s medical records. Depressive symptoms defined by The Center for Epidemiologic Studies Depression ScaleRevised (CESD-R) score of 16 or higher. CESD-R consisted of nine symptoms group and a 20-item questionnaire. These symptoms groups in patients with depressive symptoms will be counted. Patients with depressive symptoms were grouped based on a type of diabetic medication they consumed (diet only, oral antidiabetic, and insulin) and diabetic complication. From 2016 patients participated in this study, we found 235 (11.7%) patients were having depressive symptoms. The most appeared clinical manifestation in 235 patients with depressive symptoms is fatigue (88.08%), loss of interest (52.34%), sadness (41.7%), poor concentration (40.42%), and agitation (23.83%). There are more depressive symptoms in patients consuming oral antidiabetic drug than patients using insulin and diet only (70.2 vs. 28.1 vs 1.7%). More depressive symptoms are also found in patients with diabetic nephropathy than patients with diabetic neuropathy and heart disease (52.8 vs. 27.7 vs. 19.6%). These findings showed that there are many depressive symptoms in patients with T2DM, and some of most appeared clinical manifestation in depressive symptoms should be considered.
Development of E-module based on Multiple Representation to Improve the Competence of Chemical Literacy and Learning Independence of Students on the Material Reaction Rate

In The learning process, learning media, students, educators, environment conditions and everything related to education have a reciprocal relationship that is mutually dependent on each other and mutually utilizes each other with the aim of forming character in students who think cognitively and independently. The aim of this research is to determine the level of validity and practice of e-modules based on multiple representations to increase chemical literacy in odd semester class XI high school chemistry material in accordance with the independent learning curriculum. This type of research is R&D (Presearch & Development). Where this research produces products and tests the effectiveness of the products produced. Data collection techniques were carried out through interviews, validity sheets, teacher practitioner questionnaires and student response tests. The research results found that the E-module product based on multiple representations of reaction rate subject matter was very valid in terms of material validation, media validation and practitioners by teachers in the field of chemistry studies. So, it can be used in the learning process. Thus, the product developed can help teachers convey reaction rate material in an independent curriculum.
Analisis Aspek Keperilakuan terhadap Penerapan Sistem Akuntansi Persediaan pada PT. Surya Wenang Indah Manado

Sistem informasi akuntansi merupakan salah satu hal penting yang dimiliki sebuah perusahaan, termasuk di dalamnya sistem akuntansi persediaan mengingat persediaan merupakan elemen yang penting pada perusahaan dagang. Sebuah sistem yang dijalankan tidak lepas dari sumber daya manusia yang berperan untuk menjalankan sistem tersebut. Oleh karena itu, perlu adanya pertimbangan mengenai aspek keperilakuan dalam mendesain, menganalisa, mengimplementasi dan menjalankan sistem akuntansi tersebut termasuk di dalamnya menjalankan sistem akuntansi persediaan, yakni apakah sistem dijalankan dengan baik sesuai dengan tujuan perusahaan. Penelitian ini bertujuan untuk menganalisis pengaruh aspek keperilakuan terhadap sistem akuntansi persediaan yang dijalankan PT. Surya Wenang Indah sebagai perusahaan distributor barang. Metode analisis dalam penelitian ini menggunakan metode regresi linier berganda. Hasil penelitian menunjukkan bahwa aspek keperilakuan berpengaruh secara signifikan terhadap sistem akuntansi persediaan yang dijalankan perusahaan. Diharapkan perusahaan dapat lebih memperhatikan aspek keperilakuan dalam menjalankan sistem yang ada sehingga nantinya sistem dapat berjalan dengan efektif dan efisien sesuai dengan tujuan perusahaan. Kata kunci: sistem akuntansi persediaan, aspek keperilakuan
Comparative Transcriptome Analysis of High- and Low-Growth Genotypes of Eucalyptus urophylla in Response to Long-Term Nitrogen Deficiency

Nutrients play important roles in the growth and development of most plant species. However, in perennial trees, the function of nutrients in different genotypes is poorly understood. Three different nutrient levels (low, sufficient, and high nutrient levels) were applied to two contrasting Eucalyptus urophylla cultivars (a high-growth cultivar ZQUA44 and a low-growth cultivar ZQUB15), and growth and expression levels were analyzed. Although the growth traits of both genotypes under nutrient starvation treatment were much lower than under abundant nutrients, tree height, crown width, and biomass of different ZQUA44 tissues were much higher than those of ZQUB15 at all three nutrient levels. Differentially expressed genes (DEGs) clustered into six subclusters based on their expression patterns, and functional annotation showed that the DEGs involved in glutathione metabolism and flavonoid biosynthesis may be responsible for nutrient starvation across different genotypes, while the DEGs involved in carotenoid biosynthesis and starch and sucrose metabolism may have a range of functions in different genotypes. The DEGs encoding the MYB-related family may be responsible for nutrient deficiency in all genotypes, while B3 may have different functions in different genotypes. Our results demonstrate that different genotypes may form different pathways to coordinate plant survival when they face abiotic stresses.
(Im)Politeness in Dialogues between some Prophets and the Polytheists in the Noble Qur'an:

This study presents a pragmatic analysis of linguistic Politeness and Impoliteness in dialogues between six prophets (Nuh, Hud, Salih, Ibrahim, Shuaib and Musa) and their contemporaneous polytheists in the Noble Qur'an. The data comprises 35 dialogues from 20 surahs which revolve around how the prophets talked to the polytheists to persuade them to believe in the Oneness of Allah and in the Last Day and how the polytheists reacted to the prophets’ call for faith. The analytical framework comprises Leech's (1983) Maxims of Politeness, Brown and Levinson's (1978, 1987) Theory of Politeness, and Culpeper's (1996; 2005 and 2011) Model of Impoliteness. Within a mixed approach, the qualitative analysis has revealed how the prophets have been modest, sympathetic and close to their communities while guiding them to true Monotheism. In addition, the study shows how the polytheists have reacted impolitely to the prophets’ call for faith. The quantitative analysis has revealed that the six maxims of politeness have been present in the prophets’ utterances, with the Tact, Modesty and Sympathy Maxims as the most prominent. Moreover, the four strategies of politeness (Bald on record, Positive Politeness, Negative Politeness and Off-record) have been evident in the utterances of the prophets. On the other hand, all five strategies of impoliteness (Bald on record, Positive Impoliteness, Negative Impoliteness, Sarcasm or Mock Politeness and Off-record) have been employed in the polytheists’ utterances. Most significantly, the study proposes Mercy, as a potential addition to the maxims of performing Politeness. Mercy, in the form of non-reciprocal forgiveness and pity, was prevalent in the prophets’ communication with their contemporaneous people. The prophets were the finest of creation as Allah (God) chose them over humanity in order to convey the message of true Monotheism.
An understanding of environmental concepts and issues among grade 10-12 students from urban and rural schools

Several researchers have noted that the knowledge and awareness of students with regard to environmental concepts and issues are at a low level. The assumption is that pupils from urban schools are more knowledgeable about environmental concepts and issues than those from rural schools. The major aim of this study is to assess the knowledge and understanding of Grade 10-12 students about selected environmental concepts and issues such as population, ozone layer, green house effect, and acid rain. Another aim of this study is to find out whether there is any difference between the knowledge and awareness of Grade 10-12 students to environmental issues with regard to the location of their schools. This study was conducted at four secondary schools. The study involved the use of questionnaire, observation of the school settings and discussions with some students. It was found that students' knowledge and awareness of environmental issues are limited and that students from schools in urban areas had better scores than students from schools in rural areas. The results indicate that the majority of students have low levels of environmental knowledge.
Antibacterial and antifungal activity of curcumin and methylene blue associated with laser on bacterial and fungal strains

Objective: To analyze the effect of methylene blue and 10% curcumin in fungi and bacteria through an in vitro study using photodynamic therapy (PDT). Methods: Curcumin and methylene blue were photosensitized by a Photon Lase III laser applied for 90 s in a dark environment within a laminar flow chamber. Enterococcus faecalis and Candida albicans strains were cultured and standardized. Then, a minimum inhibitory concentration (MIC) assay was conducted for these photosensitizers, with concentration variations and incubation to evaluate their antimicrobial activity. Results: With PDT, Curcumin had significant antibacterial activity against E. faecalis (MIC = 250 µg/mL). In contrast, methylene blue had antibacterial activity against E. faecalis (MIC < 12.5 µg/mL with PDT) and antifungal activity against C. albicans (MIC <12.5 µg/mL with or without PDT). Both agents showed greater efficacy in the presence of the laser. The results suggest that curcumin and methylene blue associated with laser may effectively treat microbial infections. Conclusion: Further research is needed to evaluate the efficacy and safety of using these agents in animal and human models and their effectiveness against different bacterial and fungal strains.
Nts on the Incidence and Damage of Flea Beetle (Phyllotreta Nigripes) and Thrips (Megalurothrips Usitatus) on Mungbean

An experiment was conducted to evaluate the effectiveness of different treatments for the management of flea beetles and thrips of mungbean using BARI Mung-6 as experimental material. Nine treatments, viz., T1 = Use of White sticky trap, T2= Bioneem plus (Azadirachtin) 1%EC @ 1 ml/L of water at 40 DAS, T3 = Virtako (Chlorantraniliprole + Thiamethoxam) 40 WG @ 0.15g/L of water at 40 DAS, T4 = Amithrin plus 3% WDG @ 1 ml/L of water at 40 DAS, T5 = Ecomec (Abamectin) 1.8 EC @ 1 ml/L of water at 40 DAS, T6 = Nitro (Chlorpyriphos + Cypermethrin) 505 EC @ 1 ml/l of water at 40 DAS, T7 = Raise (Chlorantraniliprole) 20 SL @ 3 ml/L of water at 40 DAS and T8 = control were applied. Data were recorded on the number of flea beetles per plant, leaf area damaged by flea beetles, number of thrips-infested flowers per plant, and number of thrips per 20 opened flowers. Results revealed that the lowest number of flea beetles (3.00/m2 plants) and the highest percent reduction (64.71%) of flea beetle population over control were recorded in Virtako 80 WG at 0.15 g/L of water-treated plots. The lowest percent damage (3.75%) of leaf area and the highest percent reduction (79.73%) of leaf area damage over control were observed in Virtako-treated plots. The lowest number of thrips population (1.50/20 flowers), the highest percent of thrips population reduction (85.37%) over control, the lowest number of infested flowers (0.88/20 flowers) by thrips, and the highest percent reduction (88.65%) of flower infestation over control were found in mungbean plants treated with Raise 20 SL @ 3 ml/L of water. A strong negative correlation between the number of flea beetles and total yield was observed. There were negative relationships between the number of thrips, percent flower infestation, and total yield. Therefore, the application of Virtako 80 WG at 0.15 g/L and Raise (Chlorantraniliprole) 20 SL at 3 ml/L were found to be the best treatments for controlling flea beetles and thrips on mungbean. J. Asiat. Soc. Bangladesh, Sci. 49(2): 225-235, December 2023
Discovering the socio-economic migrant performance on illegal logging activities for deforestation problem solving in Banyuasin Regency, South Sumatera (case study of Sungai Buring traditional village)

It is often excluded from the handling of illegal logging and deforestation is the release of the socio-economic aspects in problem solving deforestation and forestry development. The purpose of this study was to: 1. Identify the socio-economic characteristics of the migrant who become illegal loggers, 2. Analyze the amount of illegal loggers' income and its allocation to the consumption, and 3. Develop a strategy to overcome illegal logging and forest deforestation based on the socio-economic characteristics of the logger. The analysis showed that socio-economic conditions of the migrant who become illegal loggers illustrates that they are still a low level of education and have productive age. Income earned Rp 4,301,211.00/year/family, lower than the income of Rp 33,070,945.00/year/family after migrating. Income get from illegal logging are Rp 13.087. 945/year/family. Average migrant allocates 60.81 % of its total income for consumption, and the remaining 39.19 % is allocated to farming and non-farming activities. This study suggests that there should be an increase in revenue breakthrough in the area of origin to be able to suppress the migration process becomes illegal loggers to other areas. Low income is the core problem of farmers to migrate. Required two basic designs: (1) social engineering with community and (2) technical engineering in the direction of the multiproduct and multifunctional forest benefits to overcome the problems of forestry in the long run.
Ectromelia Virus Affects the Formation and Spatial Organization of Adhesive Structures in Murine Dendritic Cells In Vitro

Ectromelia virus (ECTV) is a causative agent of mousepox. It provides a suitable model for studying the immunobiology of orthopoxviruses, including their interaction with the host cell cytoskeleton. As professional antigen-presenting cells, dendritic cells (DCs) control the pericellular environment, capture antigens, and present them to T lymphocytes after migration to secondary lymphoid organs. Migration of immature DCs is possible due to the presence of specialized adhesion structures, such as podosomes or focal adhesions (FAs). Since assembly and disassembly of adhesive structures are highly associated with DCs’ immunoregulatory and migratory functions, we evaluated how ECTV infection targets podosomes and FAs’ organization and formation in natural-host bone marrow-derived DCs (BMDC). We found that ECTV induces a rapid dissolution of podosomes at the early stages of infection, accompanied by the development of larger and wider FAs than in uninfected control cells. At later stages of infection, FAs were predominantly observed in long cellular extensions, formed extensively by infected cells. Dissolution of podosomes in ECTV-infected BMDCs was not associated with maturation and increased 2D cell migration in a wound healing assay; however, accelerated transwell migration of ECTV-infected cells towards supernatants derived from LPS-conditioned BMDCs was observed. We suggest that ECTV-induced changes in the spatial organization of adhesive structures in DCs may alter the adhesiveness/migration of DCs during some conditions, e.g., inflammation.
A Study on the Evaluation and Impact of Self Medication Practice Among the Pharmacy Students

Aim: To evaluate the impact of self medication practice among the pharmacy students of Andhra Pradesh in this study. Materials and Methods: This was a prospective study conducted among the pharmacy students by using the questionnaire which was circulated by means of Google forms to various pharmacy colleges located in Andhra Pradesh, India. Students from the pharmacy colleges with both the genders of all age groups were included and students other than pharmacy stream were excluded from the study. Results: In this study, a total of 473 pharmacy students were involved in order to evaluate the impact of self-medication practice among them. Most of the study participants used self-medication for headache (52%) followed by fever (38.3%) and cough (25.6%). Majority of the study participants used the drug paracetamol (78%) followed by cetirizine (38.9%) and multivitamins (25.8%) as self-medication. In this study, almost half of the study participants (48.4%) have searched the internet for selecting the drug for self-medication as most of the study participants were from urban areas. Most of the study participants always used to check the prescribing the information before self-medicating themselves (75.1%). Conclusion: Searching the treatment strategies for specific medical conditions over the internet was becoming a common phenomenon in the present generation. Responsible utilization of the self medication definitely results in positive outcomes. Hence, students should have the awareness in the aspects of rational drug usage while practicing the self medication.
Soil Microbiome in Conditions of Oil Pollution of Subarctic Ecosystems

The present study aimed to investigate the recovery of soil quality and the bacterial and fungal communities following various recultivation methods in areas contaminated with oil. Oil spills are known to have severe impacts on ecosystems; thus, the restoration of contaminated soils has become a significant challenge nowadays. The study was conducted in the forest–tundra zone of the European North-East, where 39 soil samples from five oil-contaminated sites and reference sites were subjected to metagenomic analyses. The contaminated sites were treated with different biopreparations, and the recovery of soil quality and microbial communities were analyzed. The analysis of bacteria and fungi communities was carried out using 16S rDNA and ITS metabarcoding. It was found that 68% of bacterial OTUs and 64% of fungal OTUs were unique to the reference plot and not registered in any of the recultivated plots. However, the species diversity of recultivated sites was similar, with 50–80% of bacterial OTUs and 44–60% of fungal OTUs being common to all sites. New data obtained through soil metabarcoding confirm our earlier conclusions about the effectiveness of using biopreparations with indigenous oil-oxidizing micro-organisms also with mineral fertilizers, and herbaceous plant seeds for soil remediation. It is possible that the characteristics of microbial communities will be informative in the bioindication of soils reclaimed after oil pollution.