Miracle-dz/UniFAR-FTUs huggingface dataset:
Association SOD2 and PON1 Gene Polymorphisms with Polycystic Ovary Syndrome in Saudi Women

Polycystic ovary syndrome (PCOS) is a considered one of the most common female disorders associated with reproductive, metabolic, and psychological problems. The etiology of PCOS is still not yet disclosed; however, evidence for a genetic basis has been reported. In this study, we investigate the associations between superoxide dismutase 2 (SOD2) (rs4880) and paraoxonase 1 (PON1) (rs705379) polymorphisms in PCOS in Saudi women. The study included 99 females with PCOS and 98 healthy women as a control. Single nucleotide polymorphisms (SNPs) of promoter regions were determined using TaqMan genotyping assays. Regarding the polymorphism at SOD2 (rs4880), the CC, CT, and TT genotypes were present at rates of 32, 61, and 7% in PCOS patients, and 47, 43, and 10% in controls, respectively. The frequency of the CT genotype in PCOS patients (0.61) was significantly higher than in controls (0.43) (OR = 2.05, CI: 1.16–3.61; p = 0.015). The wild homozygous genotype (CC) with the phenotype alanine appears to confer protection against the disease compared to molecules sharing at least one valine (genotypes, CT + TT). Regarding the polymorphism at PON1 (rs705379), the rates of CC, CT, and TT genotypes were 34, 50, and 16% in PCOS patients and 33, 63, and 2% in controls, respectively. The rate of the TT genotype in PCOS patients was significantly higher than that in controls (p = 0.0058). SOD2 and PON1 polymorphisms may be genetic factors that affect the occurrence of PCOS in Saudi females.
Evaluation of Tropical Cyclone Intensity Forecasts from Five Global EnsemblePrediction Systems During 2015-2019

This study presented an evaluation of tropical cyclone (TC) intensity forecasts from five global ensemble prediction systems (EPSs) during 2015-2019 in the western North Pacific region. Notable error features include the underestimation of the TC intensity by ensemble mean forecast and the under-dispersion of the probability forecasts.The root mean square errors (brier scores) of the ensemble mean(probability forecasts) generally decrease consecutively at long lead times during the five years, but fluctuate between certain values at short lead times.Positive forecast skill appeared in the most recent two years (2018-2019) at 120 h or later as compared with the climatology forecasts. However, there is no obvious improvement for the intensity change forecasts during the 5-year period, with abrupt intensity change remaining a big challenge. The probability forecasts show no skill for strong TCs at all the lead times. Among the five EPSs, ECMWF-EPS ranks the best for the intensity forecast, while NCEPGEFS ranks the best for the intensity change forecast, according to the evaluation of ensemble mean and dispersion.As for the other probability forecast evaluation, ECMWF-EPS ranks the best at lead times shorter than 72 h, while NCEP-GEFS ranks the best later on.
The Comparative Evaluation of Power Requirements for Fixed, Rotary, and Flapping Wings Micro Air Vehicles

In this paper we describe power requirements for micro air vehicles. We have researched three flight modes: fixed wing, rotary wing and flapping wing. We have calculated energy and power requirements for the three flight modes. As we can excepted, when there is no hover requirement, fixed wing flight is always most energy efficient for the micro air vehicle. However, if there is a hover requirement, the suitability of flapping or rotary wing flight is dependent on the mission profile and ambient windspeed.
Dependability and acceptability of handheld computers in school-based data collection

Given the increasing influence of technology and the explosion in data collection demands, the acceptance and assimilation of new paradigms and technologies require today's educators, researchers, and evaluators to select appropriate tools and apply them effectively. One of these technologies—handheld computers—makes the benefits of computerized data collection more accessible to field-based researchers. Three related studies were conducted to evaluate handheld-based data collection system for use in special education settings and to highlight the acceptability factors to effectively use this emerging technology. The first study reviewed the recent literature on the dependability and willingness of teachers to adopt handheld data collection systems and emphasized five important factors: (1) perceived ease of use; (2) perceived usefulness; (3) intention to use; (4) dependability; and (5) subjective norms. The second study discussed the dependability of handheld computers used by special education teachers for collecting self-report data by addressing four dependability attributes: reliability, maintainability, availability, and safety. Data were collected from five sources: (1) self-reports of time use by 19 special education teachers using Pocket PC computers, (2) observations of time use from eight external data collectors, (3) teacher interviews, (4) technical reports prepared by the researcher, and (5) teacher satisfaction. Results indicated that data collection via handheld computers yielded accurate, complete, and timely data, and was appropriate for these four dependability attributes. The last study investigated teachers' acceptance of handheld computer use by testing the relationship among five factors that influence intention to use this technology which was based on a modified version of the technology acceptance model using the handheld computer acceptance survey responses from 45 special education teachers. The results showed that intention to use handheld computer was directly affected by the devices' perceived usefulness and perceived ease of use. The issue of dependability had a direct and indirect statistically significant effect on perceived ease of use and usefulness, and intention to use a handheld computer, respectively. Overall, three studies demonstrated that handheld computers can be effectively used in the direct observation of behavior in a school environment, without requirements of any settings.
Molecular Epidemiology of BCR-ABL Rearrangement Variants in Chronic Myeloid Leukemia and Acute Lymphocytic Leukemia from Major Institute of Pakista

In Pakistan the disease burden of Chronic Myeloid Leukemia (CML) and Acute Lymphoblastic Leukemia (ALL) is quite high, yet there is a lack of scientific evidence regarding the spectrum of BCR-ABL rearrangement variants in CML and ALL. Knowing about BCR-ABL rearrangement is important in determining the prognosis and treatment strategy of disease at the time of diagnosis. This study included a total of 685 patients, out of which there were 644 CML patients and 41 ALL patients, from October 2016-July 2019. From the CML group, 270 patients were reported to have the BCR-ABL1 transcript, from which 50% were males. Whereas in the ALL group, 35 patients were reported to have the BCR-ABL1 transcript out of which 65.7% were males. Proportions of BCR-ABL transcript type differed between the two groups, with b3a2 (63.3%) and b2a2 (34.8%) transcript types having the highest frequency in CML patients, whereas e1a2 (77.1%) and b3a2 (11.3%) transcript types were found to have the highest frequency in ALL patients. Our data shows transcript genotypes in CML and ALL patients in an Asian population, which may be useful to guide the clinical management and assess prognosis. Since the majority of our CML population had the b3a2 transcript, they have a better prognosis and treatment response.
Soft Target Weight: Theory and Simulation of a Novel Haemodialysis Protocol Which Reduces Excessive Ultrafiltration

Introduction: Excessive ultrafiltration is associated with intra-dialytic symptoms, loss of residual function, and mortality in haemodialysis patients. A major contributor to excessive ultrafiltration is within-individual variation in pre-dialysis weight and the concept of achieving a fixed target weight by the end of each dialysis session. Haemodialysis protocols which allow variable post-dialysis weight have not been proposed. Methods: Weight variation was observed in haemodialysis patients and healthy controls to estimate the proportion of pre-dialysis weight variation which could be considered natural variation. These estimates were used to derive a novel protocol for setting ultrafiltration, which was evaluated by mathematical modelling. Results: Amongst 20 haemodialysis patients, mean (SD) pre-dialysis weight was 102.74 (0.94)% of target weight after a 2-day gap and 103.50 (0.94)% after a 3-day gap. Amongst 10 healthy individuals, mean (SD) daily weight was 100.0 (0.71)% of average weight. A 4-component model of pre-dialysis weight was derived using these estimates, in which the best estimate of pre-dialysis excess fluid is the midpoint of excess weight and average fluid gain, and used to propose a novel protocol for ultrafiltration setting. In simulations, the novel protocol reduced ultrafiltration variation by more than half (standard deviation 0.6 vs. 1.3% of target weight, p < 0.001), without increasing the variation in post-dialysis fluid excess. Excessive ultrafiltration rates (over 13 mL/h/kg) were far less frequent using this protocol (2.6% vs. 7.5% of sessions, p = 0.001). Conclusion: Considering natural weight variation allows the development of a novel protocol for ultrafiltration in which target weight does not have to be achieved precisely: it is therefore a soft target. This protocol, which is predicted to substantially reduce excessive ultrafiltration variation, is a zero-cost intervention with the potential to improve symptoms and clinical outcome for haemodialysis patients.
Experimental study on Noise Generation of a Two-Wheel Main Landing Gear

This paper deals with results of noise measurements for a 40% of two-wheel type aircraft main landing gear in lowspeed wind tunnel experiments. In order to accurately assess a noise source location and far-field characteristics during the approach phase, scale model with complex geometry which was equipped with small components such as link mechanism, hydraulic tubes and electrical wiring as well as a tire, a cylinder, a piston, doors, and a sidebrace was used. Model geometry was based on LEG (Landing gear noise Evaluation Geometry) which was designed by a gear manufacturer assuming 100-PAX class regional jet airliner. Experimental results obtained in two kinds of wind tunnels, which were 2m by 2m lowspeed wind tunnel in JAXA and large scale anechoic facility of Railway Technical Research Institute of Japan, showed dominant noise sources around a tire, a sidebrace, some parts of the door and also the junction between the cylinder and the sidebrace. Among these prominent noise sources, the tire and the sidebrace were large contributor to the total of noise level. It was found that noise characteristics around 1kHz was important not only in the amplitude but also in directivity for an actual aircraft scale. Representation of small components and geometry of an actual landing gear even in a scale model seemed to be effective of several decibels in noise level.
Experimental and Computational Investigation of a Dynamic Starting Method for Supersonic/Hypersonic Inlets

This paper presents the current results of experime ntal and numerical studies of a dynamic door starting method applied to a nominally two-dimensional scramjet inlet with variable contraction ratio (CR). The inlet was test ed in a Mach 4 wind tunnel with average Reynolds number of 5.77e+7 per meter, and a broad range of door rotation rates were investigated. The use of a non-ejectable, rotating inlet cover was found to improve the starting limit of overcontracted inlets by approxim ately 10%, which yielded an improvement of inlet pressure ratio of 58%. The numerical flow solver used to model each cont raction ratio was GASP v. 4.2 which uses a RANS formulation. A Roe flux-difference splitting scheme with min-mod limiting was chosen to compute the inviscid fluxes due to its strength in resolving discontinuities. The Wilcox k-ω (1998) turbulence model was used for viscous solutions and a dual-time stepping Euler implicit a lgorithm was used for time accurate predictions. Numerical results coincided well with experimental pressure measurements and shock patterns obtained from schlieren photography.
CiFi: Versatile Analysis of Class and Field Immutability

Reasoning about immutability is important for pre-venting bugs, e.g., in multi-threaded software. So far, static analysis to infer immutability properties has mostly focused on individual objects and references. Reasoning about fields and entire classes, while significantly simpler, has gained less attention. Even a consistently used terminology is missing, which makes it difficult to implement analyses that rely on immutability information. We propose a model for class and field immutability that unifies terminology for immutability flavors considered by previous work and covers new levels of immutability to handle lazy initialization and immutability dependent on generic type parameters. Using the OPAL static analysis framework, we implement CiFi, a set of modular, collaborating analyses for different flavors of immutability, inferring the properties defined in our model. Additionally, we propose a benchmark of representative test cases for class and field immutability. We use the benchmark to showcase CiFi’s precision and recall in comparison to state of the art and use CiFi to study the prevalence of immutability in real-world libraries, showcasing the practical quality and relevance of our model.
Café attachment, experiential relationship quality and experiential outcomes

ABSTRACT This study aims to examine the relationships between the dimensions of café attachment, the dimensions of experiential relationship quality and the dimensions of experiential outcomes. The findings of this study are based on structural equation modeling of a convenience sample of 482 customers drinking coffee at B;eat in Gangnam in Seoul, indicating that the proposed model fits the data. The analysis results contribute to the services marketing theory by providing additional insights into the dimensions of café attachment, the dimensions of experiential relationship quality and the dimensions of experiential outcomes. The results of this study will assist unmanned café managers in developing and implementing market-oriented service strategies to increase the dimensions of café attachment and the dimensions of experiential relationship quality and promote the dimensions of experiential outcomes.
Accessibility Difficulties, and Utilization of Healthcare Services Among Jordanian Roma with Chronic Diseases

Purpose: To examine factors that affect healthcare utilization among Roma population with chronic diseases in Jordan. It also explores behavior-seeking health care among them, their characteristics and ability to access healthcare. Design/Methodology/Approach: A cross-sectional descriptive survey performed, data collection done through in-person interviews using a structured questionnaire based on the Canadian Community Health Survey. Andersen’s behavioral model was implemented to examine the influences of predisposing, enabling, need, and outcome factors on healthcare utilization using binary logistic regression, and predictors for accessibility difficulties using multiple linear regression, Findings: 98.8% of the participants stated that they had difficulties in getting the care needed for diagnosis, treatment, or consultation, and 24.8% said that they didn’t utilize healthcare services last year. The number of chronic diseases and satisfaction level with the healthcare services significantly increase utilization, on the other hand; age, health insurance, resident location, number of chronic diseases and their duration as well as satisfaction with the healthcare are significantly affect accessibility difficulties to healthcare services. Practical implications: Provide mobile health units to reach remote settlements, that provide efficient healthcare services that met their health needs, and to be integrated with local health system. Societal implications: Efforts to involve Roma children in education. Establishing vocational training programs ended with employments. Establish sufficient and reasonable housing, to be side by side to the other population. Originality/value: This study is considered as the first to address the Jordanian Roma health status, utilization and accessibility to healthcare services, the end results help in suggesting different approaches to improve health and promote health equity.
Battling Structural Racism Against Asians in the United States: Call for Public Health to Make the “Invisible” Visible

Shortly after the Atlanta shooting of Asians on March 26, 2021, we read an article in Time magazine that hit us emotionally. Titled “‘We Are Always Waiting Our Turn to Be Important. ’ A Love Letter to Asian Americans,” Lucy Feldman wrote “a piece that says the thing I would want to read. A piece that tells me, as an Asian-American person who has deferred and cared and tried so hard to help, that I am worthy of the same. That we are worthy. You are worthy. ” Constituting 7% of the US population, Asians constitute the fastest-growing racial group, yet too often Asian Americans and Asians are invisible in America, including in public health practice, education, and policy. The COVID-19 pandemic exposed long-standing racism and discrimination against Asians. Some public officials scapegoated Asians with slurs that helped create an environment conducive to violence such as the Atlanta shooting. In this article, we discuss what makes
Cooperative learning: Buddy system in an advanced accounting subject

Co-operative learning in the form of a buddy system was adopted in teaching third year advanced accounting subject. Length of lectures were limited to incorporate more co-operative learning activities such as oral and poster presentations, jigsaws and buddy discussions. Mid-way through the course, students wrote a short reflection on their buddy experience. At the end of the course, a survey was conducted on the perceptions of students towards the buddy system and teamwork. The result of the survey indicated a positive rating towards students’ perceptions on the buddy system and teamwork and the chances of improving their grades. Findings also suggested that although there had been some resistance by the students towards the pre-selection of buddies and issues in its implementation, co-operative learning appeared to create a safer and conducive environment for students in achieving the learning outcomes.
Fostering Learners' Online Dictionary Skills through Active Dictionary Rubrics

This article aims to explore new ways to improve dictionary skills for language learners by promoting the use of active dictionary rubrics. It also tries to get a deeper understanding on how students perceive dictionaries before and after this type of training in dictionary use. To this end, a total of 75 students participated in the study and answered a questionnaire on dictionary use previous to the experiment. A second questionnaire was delivered after the instruction period to compare the users' perception of dictionary affordances. A mixed-method approach is used to collect quantitative and qualitative data via both questionnaires. This study reports on students' dictionary content awareness and how this awareness may increase by creating a habit in dictionary use routines. Keywords: dictionary use, dictionary users, dictionary rubrics, English Language Teaching (ELT), dictionary skills, online dictionaries, dictionary consultation, writing skills, learners' dictionaries, dictionary use training
A Study on Factors Affecting Marketing of Jasmine in Dindigul District

Jasmine is an attractive important commercial crop. It has got importance in all religious, social and cultural ceremonies and other functions performed by all people. The exploratory factor analysis reveals that price, lack of infrastructure, fraudulent practices and lack of export promotions are the factors affecting the marketing of jasmine. The results show that there is no significant difference between socio-economic status of jasmine growers and factors affecting marketing of jasmine. The regression analysis indicates that price is positively and significantly influences satisfaction of jasmine growers about marketing of jasmine, while, lack of infrastructure, fraudulent practices and lack of export promotions are negatively and significantly influence satisfaction of jasmine growers about the marketing of jasmine. In order to improve the jasmine marketing, the Government should formulate and implement appropriate marketing and pricing policies. The Government should create adequate storage facilities for jasmine and should take strong actions against malpractices in the marketing of jasmine. The Government and Export Promotion Council should disseminate and communicate market information and export opportunities to the jasmine growers.
Ukuran Perusahaan Sebagai Pemoderasi Pengaruh Struktur Modal, Profitabilitas, Dan Islamic Social Reporting Terhadap Nilai Perusahaan Pada Bank Umum Syariah

This study aims to determine the size of the company as a derivative of the influence of capital structure, profitability, and islamic social reporting on firm value in islamic commercial banks in Indonesia. This type of research is a quantitative study with a population of islamic commercial banks registered with OJK. The sample method of this study used a purposive sampling method in which there was a sampling with certain considerations or criteria, so that the sample obtained was 60 samples from 12 islamic commercial banks with the 2015-2019 observation period. The type of data used is panel data. The analysis method used includes descriptive statistical test, stationarity test, multiple regression test, T test, F test, R2, classical assumption test and MRA test. The Moderated Regression Analysis (MRA) test uses data processing software Eviews. The results show that partially the capital structure variable has a negative and significant effect on firm value. Meanwhile, the profitability variable has a positive and significant impact on firm value. Then, the ISR variable has a positive and insignificant effect. Based on the Moderated Regression Analysis (MRA) test, it shows that the interaction of firm size cannot detect the effect of capital structure and profitability on firm value.
Effect of Competence of Village Government Apparatus and Organizational Commitment on Village Government Performance with Village Financial Management as an Intervening Variable (Case Study in Villages in East Seunagan District, Nagan Raya Regency)

This study aims to examine the effect of competence of village government apparatus and organizational commitment on village government performance with village financial management as an intervening variable, case study in Villages in East Seunagan District, Nagan Raya Regency. The approach in this study is an associative/quantitative approach. The population in this study were Villages in East Seunagan District which consisted of 34 Villages. The sampling technique in this study used the saturated sample technique found in non-probability sampling. The research respondents were 102 people from 34 villages consisting of the Village Head, Secretary and Treasurer. Data was collected using a questionnaire which was delivered directly to the respondents. Data processing is done by structural equation modeling-partial least square (SEM-PLS). The results of this study indicate that competence of the village government apparatus effect village government performance. Organizational commitment effect village government performance. Village financial management effect village government performance. Competence of the village government apparatus effect village financial management. Organizational commitment effect village financial management. Village financial management can mediate effect of competence of the village government apparatus on village government performance. Village financial management can mediate effect of organizational commitment on village government performance.