Miracle-dz/UniFAR-FTUs huggingface dataset:
H Geoffrey Moser. Larval Fishes: Taxonomy, Distribution, and Fisheries Biology

Authors' note. -H Geoffrey Moser was one of the most influential larval-fish biologists of the past century. He was perhaps best known to ASIH members as the coeditor and motivating force behind the first ASIH Special Publication, Ontogeny and Systematics of Fishes. His other accomplishments included an extensive body of publications on larval fishes, with descriptions of development in almost 50 families and as editor of one of the most comprehensive regional identification guides for the California Current (relevant for much of the eastern Pacific and elsewhere). He co-taught courses in larval-fish identification that trained a generation of ichthyologists in that discipline. Many of those scientists have passed that skill on to younger students, continuing his legacy to the present. In addition, he was a talented illustrator and a poet. Geoff, as he was known to his colleagues and friends, passed away unexpectedly at the age of 83 on September 30, 2021. He was interviewed for this Historical Perspective by internet during the COVID-19 pandemic at his home in Bozeman, Montana, in April, 2021 by Eric Hilton and Bruce Mundy. He also provided most of the photographs. The interview was completed through questions and answers exchanged by email. Geoff was shown all of the drafts of this account. He actively contributed to it until the day before his death and approved its content.
Thermal-induced influences considered spindle unit angular contact ball bearing preload determination using embedded fiber Bragg gating sensors

As the most important segment of the spindle unit angular contact ball bearing, the preload significantly influences the bearing characteristics. Thus, the thermal-induced preload derived from the thermal expansion of spindle unit components also affects the increase in bearing temperature, stiffness, fatigue life, and ball skidding significantly. However, such preload is hard to monitor and analyze. Thus, in this article, the authors presented a fiber Bragg gating sensor-based structure for the identification of thermal-induced bearing preload. In addition, a bearing total preload control mechanism was designed with an emphasis on its thermal component. Based on the comparison of the shaft and the outer ring deformation temperature increases measured by embedded fiber Bragg gating sensors, the reasonable bearing preload range was achieved based on Hirano’s theory. Finally, the conclusions provide a reference for improving the performance of angular contact ball bearings and reducing the spindle vibration.
Health Behaviors and Health-Related Quality of Life in Female Medical Staff

The aim of this study was to evaluate the relationship between the intensity of health behaviors and health-related quality of life in female mid-level medical staff. The study group consisted of 153 female mid-level medical staff members. The intensity of health behaviors was examined with the Polish version of Health Behavior Inventory. Health-related quality of life was verified with the Short Form Health Survey questionnaire (SF 36v2). Among the participants, 33% had low, 39% average, and 28% high intensity of health behaviors. The mental component of health-related quality of life was rated higher (83.3 ± 15.3 points) compared to the physical one. The lowest health-related quality of life was observed in the domain of “bodily pain”, while the highest was found for the domain of “social functioning”. Both the physical and mental components of health-related quality of life were significantly positively correlated with health behavior prevalence in all its categories. The post-hoc tests revealed the variation in physical and mental components of HRQoL according to the level of health behavior intensity.
The impact of excessive social media use at work: a usage experience–stressor–strain perspective

ABSTRACT Excessive use of personal social media has become prevalent in the work environment and has caused significant psychological and behavioural problems among employees. These problems call for in-depth study. In this paper, we develop a usage experience–stressor–strain model to examine the consequences of excessive social media usage behaviour of employees at work, revealing the effects of different excessive usage patterns (i.e. social, hedonic, and cognitive) on employees’ psychological state (i.e. emotional exhaustion) and behavioural outcome (i.e. job performance) through dimensions of social media overload (i.e. information, communication, and social). We empirically test the research model with a survey of 422 employees who use social media at work. Our analysis presents that excessive social use at work is the major predictor of dimensions of overload. Furthermore, in contrast to the single effect of communication overload on emotional exhaustion and social overload on job performance, information overload has a significant impact on both emotional exhaustion and job performance of employees. This study advances our understanding of the complex relationships between excessive usage patterns, overload, emotional exhaustion, and job performance.
Polyphenolic HRMS Characterization, Contents and Antioxidant Activity of Curcuma longa Rhizomes from Costa Rica

Curcuma longa constitutes an important source of secondary metabolites that have been associated with multiple health benefits. For instance, curcumin, demethoxycurcumin and bisdemethoxycurcumin, have been found to perform important biological activities, such as anti-inflammatory, antioxidant, anticancer, antimicrobial, antihypertensive and anticoagulant. These promising results prompted this research to evaluate the polyphenols of C. longa rhizomes in Costa Rica. The present work reports a comprehensive study on the polyphenolic profile and the contents of the three main curcuminoids as well as the antioxidant activity of extracts from C. longa rhizomes (n = 12) produced in Costa Rica. Through UPLC-QTOF-ESI MS, a total of 33 polyphenols were identified, grouped in eight types of structures. In addition, our findings on the main curcuminoids using UPLC-DAD show all rhizomes complying with total curcuminoids (TC) content established by the United States Pharmacopeia (USP). At an individual level, samples NW-3 and NE-1 show the higher contents (118.7 and 125.0 mg/g dry material), representing more than twice the average values of the lowest samples. These samples also exhibit the highest Folin–Ciocalteu (FC) reducing capacity results as well as the best DPPH (IC50 15.21 and 16.07 µg extract/mL) and NO (IC50 between 52.5 and 54.3 µg extract/mL) antioxidant values. Further, Pearson correlation analysis findings indicated positive correlation (p < 0.05) between TC, CUR with FC results (r = 0.833 and r = 0.867 respectively) and negative correlation (p < 0.05) between CUR, TC and FC with DPPH results (r = −0.898, r = −0.911, and r = −0.890, respectively) and between NO results and DPPH (r = −0.805, p < 0.05). Finally, results for Principal Component Analysis (PCA) showed composition variability associated with their region of origin with products from the Northeastern (NE) region exhibiting higher average values for FC, TC and antioxidant activities. Further, PCA confirmed that two samples, namely NE-1 and NW-3, stand out by presenting the highest PC1 due to their particularly high TC, CUR and antioxidant activities. Consequently, our findings agree with previous results indicating the importance of C. longa extracts to elaborate products with potential benefits for health, while delivering extracts with higher levels of curcuminoids than previous reports and exhibiting high antioxidant activity.
Biodegradation of PBSA Films by Elite Aspergillus Isolates and Farmland Soil

Plastic films are widely used in current agricultural practices; however, most mulch films used are discarded and buried in the land after harvest, having adverse environmental impacts. To solve this environmental problem, the demand for biodegradable mulch has been increasing in recent years. Polybutylene succinate-co-adipate (PBSA) is a biodegradable polymer with good ductility and can be used for packaging and mulching. In this study, we isolated two elite fungal strains for PBSA degradation from farmlands, i.e., Aspergillus fumigatus L30 and Aspergillus terreus HC, and the latter showed better degradation ability than the former. It is noteworthy that biodegradation of PBSA by A. terreus is reported for the first time, which revealed unique characteristics. In the soil burial test, even the soil with relatively poor degradation ability could be improved by the addition of elite fungal mycelia. In substrate specificity analyses of soil samples, PBSA could induce the synthesis of lipolytic enzymes of indigenous microbes to degrade substrates with medium and long carbon chains in soil. Furthermore, PBSA residues or fungal mycelia supplementation in soils had no adverse effect on the seed germination rate, seedling growth, or mature plant weight of the test green leafy vegetable. Taken together, the results of this study not only advance our understanding of the biodegradation of PBSA films by filamentous fungi but also provide insight into improving the efficiency of biodegradation in soil environments.
Deep Learning–Based Brain Computed Tomography Image Classification with Hyperparameter Optimization through Transfer Learning for Stroke

Brain computed tomography (CT) is commonly used for evaluating the cerebral condition, but immediately and accurately interpreting emergent brain CT images is tedious, even for skilled neuroradiologists. Deep learning networks are commonly employed for medical image analysis because they enable efficient computer-aided diagnosis. This study proposed the use of convolutional neural network (CNN)-based deep learning models for efficient classification of strokes based on unenhanced brain CT image findings into normal, hemorrhage, infarction, and other categories. The included CNN models were CNN-2, VGG-16, and ResNet-50, all of which were pretrained through transfer learning with various data sizes, mini-batch sizes, and optimizers. Their performance in classifying unenhanced brain CT images was tested thereafter. This performance was then compared with the outcomes in other studies on deep learning–based hemorrhagic or ischemic stroke diagnoses. The results revealed that among our CNN-2, VGG-16, and ResNet-50 analyzed by considering several hyperparameters and environments, the CNN-2 and ResNet-50 outperformed the VGG-16, with an accuracy of 0.9872; however, ResNet-50 required a longer time to present the outcome than did the other networks. Moreover, our models performed much better than those reported previously. In conclusion, after appropriate hyperparameter optimization, our deep learning–based models can be applied to clinical scenarios where neurologist or radiologist may need to verify whether their patients have a hemorrhage stroke, an infarction, and any other symptom.
PENGARUH PENDIDIKAN DAN PELATIHAN (DIKLAT) TERHADAP KINEJA PEGAWAI NEGERI SIPIL DI KANTOR KECAMATAN MAPANGET KOTA MANADO

Abstract : This research is funded on the basis of initial observations based on data on Office kecematan mapanget, found still lack of employee training in the following technical-related jobs, the impact of that lead to most employees less active in carrying out his work. The method in use in the research is descriptive-quantitative methods with the population and sample as many as 21 people, and the data collection technique using three research instruments namely interview techniques, questionnaire, and observations Division. In addition to the instruments of these three researchers also conduct studies libraries by way of quoting opinion opinion expert severely bekaitan directly with the research and subsequent variable in the analysis using statistic infrensial i.e. regression analysis and correlation analysis of simple liner is simple Based on the results of data analysis, note that: a descriptive analysis results through technical analysis table (table frequency) Note that the distribution of the answers of the respondents against variable training and education (training) are on the category of "high", with the average product of 90,44%, while Employee Performance varies with the dominant category, but with the average product of 95,20%. Thus, it can be concluded that training and education (training) positive and significant effect on performance and employee kontributif. It means that the empirical basis for education and training (training and education) contribute to a real and quite big on performance, especially in Manado city mapanget Sub-District Office. Keywords: education and training (training), the performance of employees
Relationship between Standing Trunk Extension Angle and Medial Elbow Injuries in Young Baseball Pitchers

Purpose: The purpose of this study was to investigate the relationship between the standing trunk extension angle and medial elbow injuries. Subjects and methods: The study participants were 90 male baseball pitchers (10–12 years) belonging to youth baseball teams. Pitching elbow injuries were evaluated by an orthopedic surgeon using ultrasound scans and physical examination findings. A single optical three-dimensional motion analysis system was used for the trunk extension measurements, with three-dimensional coordinates captured. The overall, upper, and lower trunk angles were then analyzed. Results: Trunk extension angle during standing trunk extension was significantly smaller among participants who were positive for medial elbow injuries on ultrasound scans (positive: 71.4° ± 10.3°; negative: 75.7° ± 9.2°; t = 2.05, p < 0.05). The upper trunk extension angle was significantly smaller than the lower trunk extension angle among participants who were positive for medial elbow injuries on physical examination (upper: 33.0° ± 6.9°; lower: 41.2° ± 8.2°; t = −2.42, p < 0.05). Conclusions: Trunk extension angle during standing trunk extension is associated with medial elbow injuries. Evaluating the trunk extension angle as multiple segments rather than a single rigid body is valuable.
COX4-1 promotes mitochondrial supercomplex assembly and limits reactive oxide species production in radioresistant GBM

Glioblastoma (GBM) is a fatal disease with recurrences often associated with radioresistance. Although often effective at treating newly diagnosed GBM, increasing evidence suggests that radiotherapy-induced alterations in tumor metabolism promote GBM recurrence and aggressiveness. Using isogenic radiosensitive and radioresistant GBM cell lines and patient-derived xenolines, we found that acquired radioresistance is associated with a shift from a glycolytic metabolism to a more oxidative metabolism marked by a substantial increase in the activity of the mitochondrial respiratory chain complex cytochrome c oxidase (CcO). This elevated CcO activity was associated with a switch in the isoform expression of the CcO regulatory subunit COX4, from COX4-2 to COX4-1, assembly of CcO-containing mitochondrial supercomplexes (SCs), and reduced superoxide (O2•-) production. Overexpression of COX4-1 in the radiosensitive cells was sufficient to promote the switch from glycolytic to oxidative metabolism and the incorporation of CcO into SCs, with a concomitant reduction in O2•- production. Conversely, silencing of COX4-1 expression in normally radioresistant cells reduced CcO activity, promoted the disassembly of mitochondrial SCs, and increased O2•- production. Additionally, gain or loss of COX4-1 expression was sufficient to induce the radioresistant or radiosensitive phenotype, respectively. Our results demonstrate that COX4-1 promotes SC assembly in GBM cells, and SC assembly may in turn regulate the production of reactive oxygen species and thus the acquisition of radioresistance in GBM.
Association of Long Non-Coding RNA Growth Arrest-Specific 5 Genetic Variants with Diabetic Retinopathy

The aim of this work was to appraise the potential associations of single nucleotide polymorphisms (SNPs) of long non-coding RNA growth arrest-specific 5 (GAS5) with diabetic retinopathy (DR) in a diabetes mellitus (DM) population. Two loci of the GAS5 SNPs (rs55829688 and rs145204276) were genotyped via TaqMan allelic discrimination in 449 non-DR patients and 273 DR subjects. The SNP rs145204276 Del/Del showed a significantly higher distribution in the DR group compared to the non-DR group (AOR: 2.487, 95% CI: 1.424–4.344, p = 0.001). During subgroup analyses, the non-proliferative diabetic retinopathy (NPDR) subgroup demonstrated a significantly higher ratio of the SNP rs145204276 Del/Del (AOR: 2.917, 95% CI: 1.574–5.406, p = 0.001) and Ins/Del + Del/Del (AOR: 1.242, 95% CI: 1.016–1.519, p = 0.034) compared to the non-DR population, while the proliferative diabetic retinopathy (PDR) subgroup did not reveal significant differences in either SNP rs145204276 or rs55829688 distributions compared to the non-DR group. Furthermore, patients with a GAS5 SNP rs145204276 Del/Del showed a significantly shorter DM duration than the wild type (Ins/Ins) (p = 0.021). In conclusion, our findings demonstrate that the GAS5 SNP rs145204276 Del/Del variant is associated with an increased susceptibility to DR in DM patients, particularly in those patients with NPDR.
GLP1 Exerts Paracrine Activity in the Intestinal Lumen of Human Colon

GLP1 produced in the upper part of the gut is released after food intake and acts by activating insulin secretion, but the role of GLP1 in the colon, where it is predominantly produced, remains unknown. Here we characterized the apical versus basolateral secretion of GLP1 and PYY and the paracrine mechanisms of action of these enterohormones in the human colon. We stimulated human colon tissue in different ex vivo models with meat peptone and we used immunofluorescence to study the presence of canonical and non-canonical receptors of GLP1. We found that PYY and GLP1 are secreted mainly at the gut lumen in unstimulated and stimulated conditions. We detected DPP4 activity and found that GLP1R and GCGR are widely expressed in the human colon epithelium. Unlike GLP1R, GCGR is not expressed in the lamina propria, but it is located in the crypts of Lieberkühn. We detected GLP1R expression in human colon cell culture models. We show that the apical secretion of PYY and GLP1 occurs in humans, and we provide evidence that GLP1 has a potential direct paracrine function through the expression of its receptors in the colon epithelium, opening new therapeutic perspectives in the use of enterohormones analogues in metabolic pathologies.
Optimal Management of Patients with Severe Coronary Artery Disease Following Multidisciplinary Heart Team Approach—Insights from Tertiary Cardiovascular Care Center

Background: The purpose of this retrospective study was to investigate outcomes of patients with severe coronary artery disease (CAD) after implementing various treatment strategies following multidisciplinary Heart Team (MHT) discussion. Methods Primary and secondary endpoints and quality of life during a mean (SD) follow-up of 37 (14) months of patients with severe CAD (three-vessel [3-VD] or/and left main [LM] disease) qualified after MHT discussion to optimal medical treatment (OMT) alone, OMT and coronary artery bypass grafting (CABG), or OMT and percutaneous coronary intervention (PCI) were evaluated. As the primary endpoint, major adverse cardiac or cerebrovascular events (MACCE) (i.e., death from any cause, stroke, myocardial infarction, or repeat/need for revascularization) were considered. Result: From 2016 to 2019, 176 MHT meetings were held, and a total of 1286 participants with severe CAD and completely implemented MHT decisions (OMT, CABG, or PCI for 251, 356, and 679 patients, respectively) were included. The occurrence of the primary endpoint was significantly increased in OMT-group (154 (61.4%) vs. CABG and PCI groups—110 (30.9%) and 302 (44.5%) patients, respectively (p < 0.05). For interventional strategies only—CABG was associated with reduced rates of MACCE and repeat revascularization, while the superiority of PCI for stroke and disabling stroke was observed (p < 0.05). The general health status assessed at the end of the follow-up was significantly better for patients who underwent CABG or PCI than in the OMT group (p < 0.05). Conclusions: In this real-life study, we presented a single-center experience of providing optimal medical care for patients with severe CAD following MHT discussion.
The Business case for ethics : why good guys finish first

This study puts forward a business case for ethical behaviour in organisations. Data was collected over 5 years, coming from 18 countries, 16,813 staff from 1,535 organisations participated and approximately 18% of the database is international. Organisations came from an extensive range of industry groups. Findings included that businesses perceived as successful demonstrated a strong link to ethical behaviour and also had more engaged staff. Our analysis also indicated that there is an argument for linking good leadership and good ethical behaviour. Managers should consider the importance of promoting good ethical behaviour for a successful business.
Investigations of Cyber Bullying and Traditional Bullying in Adolescents on the Roles of Cognitive Empathy, Affective Empathy, and Age

the Therefore, the purpose of this research was to investigate the relationships between traditional bullying (verbal, physical, and relational) and cyber bullying based on the roles of cognitive empathy, affective empathy and age among adolescents. Three instruments to collect data were the Interpersonal Reactivity Index to measure the level of empathy, the Adolescent Peer Relations Instrument to measure the level of traditional bullying, and the Adolescent Peer Relations Instrument to measure the level of cyber bullying behavior. The sample in this research was 685 female students and 538 male students from three private high schools in Surabaya, Indonesia. Proportionally stratified samples were used to determine the sample. The data obtained were analyzed using Pearson Product-moment and Multiple Regression. The results showed that males were more often involved in bullying than females, and the level of empathy (cognitive and affective) of males was lower than females. It was only affective empathy that was significantly negatively related to traditional bullying. Age also correlated positively with traditional bullying, and the higher the age in the adolescents, the more they engaged in traditional bullying. The implication of this research was highlighting the role of affective empathy as part of efforts to prevent bullying and and to solve various bullying-related
Filling the gap: A microscopic zooarchaeological approach to changes in butchering technology during the Early and Middle Bronze periods at Tall Zirā´a, Jordan

ABSTRACT The Early Bronze Age (3500–2000 bce) of the southern Levant experienced the development of bronze metal technology, but the rate and nature of its dissemination beyond the elite are unclear. In the southern Levant and elsewhere, based upon the microscopic analysis of butchering marks, it has been proposed that bronze slicing tools only begin to be used in quantities in the Middle Bronze. However, previous analyses have always lacked data sets from the Early Bronze IV/Middle Bronze I period (c. 2500–2000 bce). In this paper, we present the butchered animal bone data from the site of Tall Zirā´a (in the NW corner of Jordan) where there is a fuller chronological sequence for the Early and Middle Bronze Ages. These data provide a unique opportunity to investigate long-term changes in butchering practices in the southern Levant. The analysis demonstrates that the new (bronze) technology does not seem to be integrated into quotidian activities, such as the processing of animal carcasses, until well into the Middle Bronze Age (MB IIB). Until then, and in subsequent phases of the MB, the majority of butchering marks are made by stone implements.