Miracle-dz/UniFAR-FTUs huggingface dataset:
The Intention to Use E-Money: An Empirical Study of Halal Food SMEs In Surakarta

Entering Financial Technology (FINTECH) era, Indonesian Banks and financial institutions competing in issuing their electronic money product. E-money potentially used by Small and Medium Enterprises (SMEs) for doing business and making transactions but in reality it is not so. Halal food SMes E-money usage still low so its important for fintech companies to be able to know and understand perceptions to increase interest in re-transacting using electronic money. However, these is still few studies discussed behavioral intention to use e-money in SMEs sector. Consequently, This study identifies and examines the factors that contribute to behavioral intention to use e-money in Surakarta from the Halal food SMEs perspective . Data for this study were obtained through a mail survey sent to 125 Halal Food SMEs in Surakarta, Jawa Tengah. Regression is used to analyze the data and determine the impact the factors have on behavioral intention to use e-money. The regression results confirm that perceived usefulness, perceived ease of use, perceived behavioral control are the most likely factors that contribute to halal food SMEs intention to use e-money whereas trust was not significantly related. Implications of the findings for developers are discussed further.
Numerical Study of Evaporation Modelling for Different Fuels at High Operating Conditions in a Diesel Engine

A fuel injection system in a diesel engine has different processes that affect the complete burning of the fuel in the combustion chamber. These include the primary and secondary breakups of liquid fuel droplets and evaporation. In the present paper, evaporation of two different diesel fuels has been modelled numerically. Evaporation of n-heptane and n-decane is governed by the conservation equations of mass, energy, momentum, and species transport. Results have been plotted by varying the droplet diameter and temperature. It was observed that droplet size, temperature of droplets, and ambient temperature have notable effect on the evaporation time of diesel fuel droplets in the engine cylinder.
No Protective Effects of Hair Cells or Supporting Cells in Ototoxically Deafened Guinea Pigs upon Administration of BDNF

We investigated whether treatment with brain-derived neurotrophic factor (BDNF), which is known to protect spiral ganglion cells (SGCs), could also protect hair cells (HCs) and supporting cells (SCs) in the organ of Corti of a guinea pig model of sensorineural hearing loss. Hearing loss was induced by administration of kanamycin/furosemide and two BDNF treatments were performed: (1) by gelatin sponge (BDNF-GS) with acute cochlear implantation (CI), and (2) through a mini-osmotic pump (BDNF-OP) with chronic CI. Outer HCs (OHCs), inner HCs (IHCs), Border, Phalangeal, Pillar, Deiters’, and Hensen’s cells were counted. The BDNF-GS cochleas had significantly fewer OHCs compared to the untreated ones, while the IHC and SC numbers did not differ between treated and untreated cochleas. The BDNF-OP group showed similar cell numbers to the untreated group. SGC packing density was not correlated with the total number of SCs for either BDNF group. Our data suggest that: (1) BDNF does not prevent cell death in the organ of Corti, and that the protection of SGCs could result from a direct targeting by BDNF; (2) BDNF might induce a different function/activity of the remaining cells in the organ of Corti (independently from cell number).
Quantity and specialisation matter: Effects of quantitative and qualitative variation in willow chemistry on resource preference in leaf‐chewing insects

Plants produce multiple specialised metabolites to defend themselves against insect herbivores. Phytochemical diversity plays important roles in plant–insect interactions, but specific roles of its various dimensions are poorly known. Interspecific chemical β‐diversity represents variation in presence of species‐specific metabolites or quantitative variation in concentrations of metabolites common to several plant species. We hypothesised that qualitative and quantitative variation in plant chemistry can have differential effects on herbivores from various insect orders. We linked phytochemical variation in willow salicylates (Salicaceae‐specific metabolites) and flavonoids (widespread metabolites) to a standardised distance‐based specialisation index (DSI*) in three orders of leaf‐chewing insects: sawfly larvae, beetles, and caterpillars. In beetles, average DSI* accounting for host chemical β‐diversity did not differ from DSI* disregarding host chemistry. Levels of chemical specialisation did not differ among beetle species feeding only on Salicaceae and those using other plant families, suggesting that both can overcome willow chemistry by alternative physiological or behavioural adaptations. Contrastingly, sawflies and caterpillars responded to willow chemistry, with their DSI* corresponding mainly to quantitative differences in willow metabolites. The DSI* accounting for salicylates did not differ from the one accounting for flavonoids in either of the two orders. Our results suggest that β‐diversity in plant chemistry has differential effects on insect herbivores depending on their order and chemical β‐diversity measurement used. Our results emphasise the importance of quantitative variation in plant chemical composition, suggesting that it does not always have to be rare or species‐specific metabolites that drive host‐choice of leaf‐chewing insects.
Multicenter surveillance of in vitro activities of cefepime-zidebactam, cefepime-enmetazobactam, omadacycline, eravacycline, and comparator antibiotics against Enterobacterales, Pseudomonas aeruginosa, and Acinetobacter baumannii complex causing bloodstream infection in Taiwan, 2020

ABSTRACT Objectives To determine the in vitro activities of novel and comparator antibiotics against Gram-negative bacteria (GNB) in Taiwan. Methods Isolates of Escherichia coli (n = 335), Klebsiella pneumoniae (n = 316; 144 isolates with hyperviscosity characteristics), Pseudomonas aeruginosa (n = 271), Acinetobacter baumannii complex (n = 187), and non-typhoidal Salmonella species (n = 226), Shigella species (n = 13) from miscellaneous culture sources were collected in 2020 in Taiwan. The MICs of the isolates to test antibiotics were determined using the broth microdilution method. GeneXpert was used to detect genes encoding carbapenemases among the carbapenem-non-susceptible (NS) Enterobacterales isolates. Results The MIC values of the cefepime-enmetazobactam combination against extended-spectrum β-lactamase-producing E. coli and K. pneumoniae isolates (MIC90 ≤ 0.5 mg/L), bla KPC-harboring E. coli isolates (0.25 mg/L; n = 2), and 80% of bla OXA-48-like gene-harboring K. pneumoniae isolates (≤2 mg/L) were low. The MIC ranges of the cefepime-zidebactam against carbapenemase-producing Enterobacterales isolates (irrespective of the carbapenemase type [MIC90 ≤ 4 mg/L]) and carbapenem-NS or ceftolozane-tazobactam-NS P. aeruginosa isolates (MIC90 value, 8 mg/L) were significantly lower than those of the cefepime-enmetazobactam. Conclusions The efficacy of novel antibiotics against important drug-resistant GNB must be monitored and validated during the clinical treatment of patients.
A new technique for forecasting hourly load for long-term planning

An electric utility should plan its system well ahead of time to meet future customer demand. It is essential to an appropriate long-term generation expansion plan, with a usual duration of 20 to 25 years, that the forecasted load be close to the demand that will occur at each moment of the planning period. The authors present a methodology to forecast the hourly load or load for smaller interval of time for long-term generation expansion planning. The methodology is based on the relation between the forecasted annual/seasonal peak load and the probability density functions (PDFs) of different load ratios. The article validates the proposed methodology by applying it to the power system of Bangladesh Power Development Board.
Automated valve condition classification of a reciprocating compressor with seeded faults: experimentation and validation of classification strategy

This paper deals with automatic valve condition classification of a reciprocating processor with seeded faults. The seeded faults are considered based on observation of valve faults in practice. They include the misplacement of valve and spring plates, incorrect tightness of the bolts for valve cover or valve seat, softening of the spring plate, and cracked or broken spring plate or valve plate. The seeded faults represent various stages of machine health condition and it is crucial to be able to correctly classify the conditions so that preventative maintenance can be performed before catastrophic breakdown of the compressor occurs. Considering the non-stationary characteristics of the system, time–frequency analysis techniques are applied to obtain the vibration spectrum as time develops. A data reduction algorithm is subsequently employed to extract the fault features from the formidable amount of time–frequency data and finally the probabilistic neural network is utilized to automate the classification process without the intervention of human experts. This study shows that the use of modification indices, as opposed to the original indices, greatly reduces the classification error, from about 80% down to about 20% misclassification for the 15 fault cases. Correct condition classification can be further enhanced if the use of similar fault cases is avoided. It is shown that 6.67% classification error is achievable when using the short-time Fourier transform and the mean variation method for the case of seven seeded faults with 10 training samples used. A stunning 100% correct classification can even be realized when the neural network is well trained with 30 training samples being used.
The foreign direct investment-Export performance nexus: An ARDL based empirical evidence from Ethiopia

Abstract Ethiopia is one of the top FDI destinations in Africa and the leading FDI receiver in east Africa. However, little is known about the direct impact of the FDI on the Ethiopian export performance. This study was conducted to fill this gap. As a result, the main objective of this study was to examine the empirical relationship between foreign direct investment and export performance in Ethiopia by using an annual time series data for the period 1992–2018. The analysis was based on the autoregressive distributed lag (ARDL) model. The long-run model result, which was estimated after a proper application of pre-estimation tests, displayed that the relationship between FDI and export performance was insignificant. The estimated long-run equation also revealed that an increase in the real GDP resulted in an improved export performance in Ethiopia. The coefficient of the real effective exchange rate index in the long-run equation implies that depreciation of the exchange rate improves the export performance. According to the short-run and long-run estimation results, the study provides recommendations to improve Ethiopian export performance. First, national economic policies have to be directed toward keeping the overall health of the economy safe and achieving fast and sustainable growth. Second, with regarding to exchange rate management, long-term effects need to be considered. Finally, attracting more foreign firms to engage in value addition activities for the primary agricultural products would also play a role in enhancing the export performance.
POLIMORPHIC CHARACTERIZATION OF ESR1 AND FOXL2 GENES AND THE ASSOCIATION OF THEIR INTERACTION WITH PRODUCTIVE TRAITS OF BROWN LOCAL IRAQI CHICKENS

The estrogen receptor 1(ESR1) and fork-head box L2 (FOX L2) genes play a pivotal role in regulation of egg formation in poultry. this study aimed to investigate interaction between ESR1 and FOXL2 in the productive performance of brown local Iraqi chickens (BLIC). A total of 104 BLIC represented from the F4th generation of local chicken selected for high egg productions were used. Two novel single nucleotide polymorphism (SNPs), one of them in ESR1 (T57198C) intron 3, and another of FOX L2 (C919T) gene within encoding region were identified through PCR-DNA sequencing. Six haplotypes (H1=TTCC, H2=TTCT, H3=TCCC, H4=TCCT, H5=CCCC, H6=CCCT) were obtained due to interaction between these two SNPs. Chi-square analysis showed no significant in genotypic and allelic frequencies for each SNP which revealed that both genes were agreement with Hardy-Weinberg equilibrium. Association analysis of haplotypes with production traits revealed that individuals have H4 genotype achieved higher body weight at sexual maturity, at 60 weeks of age and egg weight at 45 and 60 weeks of age, whereas, the higher number of eggs were exhibited in individual with H6 from onset egg till 60 weeks of age. The two haplotypes; H4(TCCT) and H6(CCCT) showed better combination than others with respect to production performance. In conclusion, our findings provided new evidence that the two genes (ESR1 and FOXLl2) with special interaction may have potential effects on productive traits of chickens and beneficial effects in laying breeding programs.
Sero-epidemiology of Toxocara canis infection in people attending four educational and therapeutic centres in Alborz Province, Iran

Introduction and Objective. Toxocariasis is a common but neglected zoonotic disease caused by the larval stage of Toxocara species. The aim of this study is to highlight the sero-epidemiology of Toxocara canis infection in the general population of Alborz Province, Iran. Materials and method. Anti-Toxocara canis antibodies were tested in 234 studied inhabitants by enzyme-linked immunosorbent assay (ELISA). Demographic characteristics and consent were obtained from each individual. Results. In total, 33 (14.1%) of the 234 participants (mean age 19.6±8.7 years) had anti-Toxocara canis antibodies. Prevalence of infection was higher in males (16.2%) than females (12.4%). High-titer antibodies were most prevalent among the subjects aged ≤ 20 years, and showed statistical significance (p=0.001). There was significant association between the presence of Toxocara antibodies and the place of residence, keeping dog at home, and contact with contaminated soils (p<0.05). This is the first report of the sero-prevalence and contributing factors for Toxocara canis infection in the general population in
Cost evaluation of desalination and sewage treatment based on plants operated in Oman and use of software models

AbstractThe performance of desalination and sewage treatment plants operated by contractors at sites of a large company in Oman was evaluated in relation to benchmark costs. Such benchmark costs, which are dependent on plant size and process used, were established based on estimates provided in research literature and based on site-specific estimates made using software models. Desalination economic evaluation program software was used to estimate site-specific costs of desalination and financing for environmental, affordable, and strategic investments that bring on large scale expenditure software was used to estimate site-specific costs of sewage treatment. The estimated site-specific benchmark cost of desalination was 1.20 US$/m3. The desalination cost subject to many variables reported in the literature ranges between 0.52 and 1.30 US$/m3. The estimated site-specific benchmark operational cost of sewage treatment up to the BOD level of 10–15 mg/L of treated water was 0.29 US$/m3. The cost of sewage wa.
Trends of Clinical Outcomes of Patients with Advanced Hepatocellular Carcinoma Treated with First-Line Sorafenib in Randomized Controlled Trials

Background: Sorafenib has consistently served as the control arm in multiple randomized clinical trials (RCTs) evaluating novel therapies for advanced hepatocellular carcinoma (HCC) for more than a decade. Analyzing trends in clinical outcomes of patients treated with sorafenib for the same indication over time offers the opportunity for unique insight into the evolution of clinical trial conduct and potential non-drug factors impacting outcomes. Methods: We identified RCTs in patients with treatment-naïve advanced HCC where sorafenib was compared to another systemic therapy or placebo. We extracted trial-level demographic, clinicopathologic, and outcome data (overall survival [OS], progression-free survival [PFS], objective response rate [ORR], and duration of therapy). Sample-weighted linear regression was used to identify temporal trends with significance set at p ≤ 0.05. Results: Sixteen RCTs (9 phase III and 7 phase II) enrolling 4,086 patients treated with sorafenib were included in the analysis. Included trials enrolled patients from 2005 to 2019. OS has significantly improved by 4.5 months from 2005 to 2019 (p = 0.048) over time. Thirteen studies provided data on PFS using Response Evaluation Criteria in Solid Tumors (RECIST) 1.1, with no significant change over time (p = 0.69). ORR assessed by RECIST 1.1 has significantly improved by 6.0% over time (p = 0.003). Median duration of therapy with sorafenib has decreased by 53% since the enrollment of the first clinical trial in 2005, from 23.1 weeks to 12.2 weeks (p = 0.0037). There was no significant change in patient demographics were identified over time to explain the OS findings. Conclusion: The median OS of patients with advanced HCC treated with sorafenib has improved significantly over 15 years. At the same time, the median duration of therapy with sorafenib has decreased. The reason for these findings was not explained by changing demographics of patients enrolled in these trials and has implications for ongoing clinical trials.
EUROPEAN TRADITIONAL IRRIGATION IN TRANSITION PART I: IRRIGATION IN TIMES PAST—A HISTORIC LAND USE PRACTICE ACROSS EUROPE

Whereas the importance of traditional irrigation in southern Europe is well known, its role in the ecological history of rural landscapes elsewhere in Europe is often overlooked. This two‐part review aims to advance understanding of the historical and present role of traditional irrigation farming schemes in Europe. It confirms that, prior to the industrial era, irrigation had been an essential part of farming for centuries. It was practised in very different, often contrasting, environmental regions across Europe. The historical spread of the schemes is presented in a map. Two ‘golden ages’ of traditional irrigation in Europe can be identified: the first in the High Middle Ages along with the introduction and widespread adoption of the three‐field system, and the second in the late eighteenth up to the first half of the twentieth century with reorganization of this agricultural system. Due to the complex character of past irrigation functioning, scientific understanding of processes and long‐term impacts is difficult, but ultimately all irrigation farming enterprises were driven by the purpose of increasing yields. Apparently the traditional schemes were the result of an evolution process over the course of centuries characterized by steady optimization and adaptation to historic and local conditions. Copyright © 2014 John Wiley & Sons, Ltd.
Dynamic Phenotypic Switching and Group Behavior Help Non-Small Cell Lung Cancer Cells Evade Chemotherapy

Drug resistance, a major challenge in cancer therapy, is typically attributed to mutations and genetic heterogeneity. Emerging evidence suggests that dynamic cellular interactions and group behavior also contribute to drug resistance. However, the underlying mechanisms remain poorly understood. Here, we present a new mathematical approach with game theoretical underpinnings that we developed to model real-time growth data of non-small cell lung cancer (NSCLC) cells and discern patterns in response to treatment with cisplatin. We show that the cisplatin-sensitive and cisplatin-tolerant NSCLC cells, when co-cultured in the absence or presence of the drug, display dynamic group behavior strategies. Tolerant cells exhibit a ‘persister-like’ behavior and are attenuated by sensitive cells; they also appear to ‘educate’ sensitive cells to evade chemotherapy. Further, tolerant cells can switch phenotypes to become sensitive, especially at low cisplatin concentrations. Finally, switching treatment from continuous to an intermittent regimen can attenuate the emergence of tolerant cells, suggesting that intermittent chemotherapy may improve outcomes in lung cancer.
Observing the Challenges of Implementing New Health ICT

Research into the development and adoption of new health technologies finds that information and communication technology (ICT) developers often fail to understand the clinical workplace, resulting in the implementation of costly systems that stakeholders reject. Here we report observations of the implementation of a well-designed new patient information system at a regional hospital. We used a combination of ethnographical and survey methods to assess stakeholders‘ uptake of and reactions to the new system. We found that even with a well-designed system, uptake can encounter challenges. We outline a number of important factors that may influence the success, or failure, of new ICT.
NOx-Abatement Potential of Lean-Premixed GT Combustors

The influence of the structure of perfectly premixed flames on NO formation is investigated theoretically. Since a network of reaction kinetics modules and model flames is used for this purpose, the results obtained are independent of specific burner geometries. Calculations are presented for a mixture temperature of 630 K, an adiabatic flame temperature of 1840 K, and I and 15 bars combustor pressure. In particular, the following effects are studied separately from each other: . molecular diffusion of temperature and species . flame strain . local quench in highly strained flames and subsequent reignition . turbulent diffusion (no preferential diffusion) . small scale mixing (stirring) in the flame front Either no relevant influence or an increase in NO production over that of the one-dimensional laminar flame is found. As a consequence, besides the improvement of mixing quality, a future target for the development of low-NO x burners is to avoid excessive turbulent stirring in the flame front. Turbulent flames that exhibit locally and instantaneously near laminar structures (flamelets) appear to be optimal. Using the same methodology, the scope of the investigation is extended to lean-lean staging, since a higher NO x -abatement potential can be expected in principle. As long as the chemical reactions of the second stage take place in the boundary between the fresh mixture of the second stage and the combustion products from upstream, no advantage can be expected from lean-lean staging. Only if the primary burner exhibits much poorer mixing than the second stage can lean-lean staging be beneficial. In contrast, if full mixing between the two stages prior to afterburning can be achieved (lean-mix-lean technique), the combustor outlet temperature can in principle be increased somewhat without NO penalty. However, the complexity of such a system with a larger flame tube area to be cooled will increase the reaction zone temperatures, so that the full advantage cannot be realized in an engine. Of greater technical relevance is the potential of a lean-mix-lean combustion system within an improved thermodynamic cycle. A reheat process with sequential combustion is perfectly suited for this purpose, since, first, the required low inlet temperature of the second stage is automatically generated after partial expansion in the high pressure turbine, second, the efficiency of the thermodynamic cycle has its maximum and, third, high exhaust temperatures are generated, which can drive a powerful Rankine cycle. The higher thermodynamic efficiency of this technique leads to an additional drop in NO x emissions per power produced.