Miracle-dz/UniFAR-FTUs huggingface dataset:
Effectiveness of Topical Hyaluronic Acid Versus Chlorhexidine Mouthwashes in The Treatment of Recurrent Aphthous Stomatitis: A Randomized Clinical Trial

Abstract Background: Recurrent aphthous stomatitis (RAS) is the most common disorder affecting oral mucosa. The present study was designed to assess the clinical effectiveness of utilizing topical hyaluronic acid (HA) against chlorhexidine (CHX) mouthwashes as a control in RAS treatment. Materials and methods: Thirty-four patients with minor RAS were included in the trial. They were equally allocated into two groups with random distribution to rinse with CHX mouthwash as a control (Group I, CHX Group) and HA mouthwash in (Group II, HA group) as a study group. Evaluation of pain intensity and ulcer size were done in all study patients at baseline, 3 days and 7 days observational times. Duration of healing period was assessed in both study groups. Results: The results demonstrated a significant lowering in pain score and ulcer size in each group. Lower mean values of these outcomes were recorded in HA group compared to CHX group at 3 days and 7 days with significant difference regarding pain score. Concerning the duration of healing a significant decrease was recorded in HA group compared to CHX group. Conclusion: In conclusion, topical HA is a safe and effective treatment option for RAS with better pain control and healing duration.
Effect of dietary oils from various sources on carbohydrate and fat metabolism in mice

Background Dietary oils differ in their fatty acid composition and the presence of additional microcomponents (antioxidants, etc.). These differences are thought to invoke different biochemical pathways, thus affecting fats and carbohydrates metabolism differently. Olive oil (OO) and soybean oil (SO) are common vegetable oils in the local cuisine. Peanuts oils of local varieties are viewed as potential sources of dietary vegetable oils, especially in the food industry. Objective We examined the effect of four different dietary vegetable oils on carbohydrate and lipid metabolism in mice. The selected oils were OO, high in oleic acid, extracted from cultivated high oleic acid peanut (C-PO), regular peanut oil (PO), and SO. Design In this study, 32 male C57BL/6J mice were randomly divided into four groups (n = 8 in each group) and were fed with four different diets enriched with 4% (w/w) dietary vegetable oils (OO, C-PO, PO, or SO). After 10 weeks, the mice were sacrificed. Western blot was used to examine proteins such as phospho-AMP-activated protein kinase (p-AMPK), ace-tyl-CoA carboxylase (ACC), cluster of differentiation 36 (CD36), and Sirtuin 1 (SIRT1), whereas real-time polymerase chain reaction (PCR) was used to examine the expression of sterol regulatory element-binding protein-1c (SREBP-1C), fatty acid synthase (FAS), glucose-6-phosphatase (G6Pase), and CD36 transcripts. Results In mice-fed SO, lipid accumulation was predominately in adipose tissue, accompanied a tendency decrease in insulin sensitivity. Mice-fed OO had lower plasma triglycerides (TG) and increased hepatic CD36 gene expression. The C-PO group presented lower messenger RNA (mRNA) levels in the liver for all examined genes: SREBP-1c, FAS, G6Pase, and CD36. There were no significant differences in weight gain, plasma cholesterol and high-density lipoprotein (HDL) cholesterol levels, hepatic ACC, SIRT1, AMPK, and CD36 protein levels or in liver function among the diets. Discussion It seems that as long as fat is consumed in moderation, oil types may play a lesser role in the metabolism of healthy individuals. Conclusion This finding has the potential to increase flexibility in choosing oil types for consumption.
A cross-sectional study on age-related development of rebound and counter movement jumping ability

A study was conducted to investigate the age-related development of rebound and counter movement jumping ability. A total of 1137 boys (6 yr: 59, 7 yr: 82, 8 yr: 69, 9 yr: 142, 10 yr: 105, 11 yr: 169, 12 yr: 103, 13 yr: 110, 14 yr: 77, 15 yr: 66, 16 yr: 73, and 17 and 18 yr: 82) conducted counter movement jumping (CMJ) as a non-ballistic movement and five-repeated rebound jumping (5RJ) as a ballistic movement. Jumping ability was assessed using CMJ jumping height and the value obtained by dividing jumping height by the ground contact time in 5RJ (RJ-index). CMJ jumping height and the RJ-index in 5RJ increased in accordance with growth. Development of the RJ-index in 5RJ depended on the increase in jumping height, because ground contact time did not change even though jumping height increased with growth. There was a significant correlation between CMJ jumping height and RJ-index in 5RJ (r=0.765, p<0.001, r2=0.585). Division of jumping ability types was based on±1SD of the residual. These types were as follows: CMJ ability corresponded to RJ ability (CMJ=RJ: n=810), RJ ability was superior to CMJ ability (Good RJ: n=165) and RJ ability was inferior to CMJ ability (Poor RJ: n=162). The number of Good RJ and Poor RJ types increased between the ages of 9-13 years, which is the onset of the growth spurt. These results suggest that CMJ jumping height and RJ-index in 5RJ increase in accordance with growth, but the processes of age-related development of both types of jumping ability do not necessarily correspond to each other, and developmental differences between individuals tend to increase at the onset of the growth spurt.
Microphones, not megaphones: Functional crowdworker voice regimes on digital work platforms

Digital work platforms are often said to view crowdworkers as replaceable cogs in the machine, favouring exit rather than voice as a means of resolving concerns. Based on a qualitative study of six German medium-sized platforms offering a range of standardized and creative tasks, we show that platforms provide voice mechanisms, albeit in varying degrees and levels. We find that all platforms in our sample enabled crowdworkers to communicate task-related issues to ensure crowdworker availability and quality output. Five platforms proactively consulted crowdworkers on task-related issues, and two on platform-wide organisation. Differences in the ways in which voice was implemented were driven by considerations about costs, control and a crowd’s social structure, as well as by platforms’ varying interest in fair work standards. We conclude that the platforms in our sample equip crowdworkers with ‘microphones’ by letting them have a say on workflow improvements in a highly controlled and easily mutable setting, but do not provide ‘megaphones’ for co-determining or even controlling platform decisions. By connecting the literature on employee voice with platform research, our study provides a nuanced picture of how voice is technologically and organisationally enabled and constrained in non-standard, digital work contexts.
Carotid Artery Flow Volume and Velocity during Isometric Exercise in the Supine and Sitting Positions in Healthy Men

Rehabilitation was performed for a 51-year-old woman with left upper arm palsy and bilateral hip disarticulation due to osteomyelitis after traffic injury. The patient underwent muscle strength training, and a special sitting orthosis was designed. After the rehabilitation, the patient could keep a sitting position without orthosis. The sitting orthosis made the patient to keep a sitting position for a long time without low back pain. Using a bar and a sliding board, the patient could get the transfer ability. Many activities of daily living became independent by keeping a sitting position. Not only a function, but also a physical activity was improved. Before rehabilitation the patient was overweighted and the blood glucose level was high because of low energy expenditure. Muscle strength training and keeping a sitting position made the patient activity-induced energy expenditure. The body weight was reduced from 65kg to 58kg. And a blood sugar level became well controlled. Gain a sitting position is important for the patient with lower leg amputation.
Influences of Career Planning, Leadership and Organizational Culture towards Employee Work Effectiveness

This study was conducted at the Regional Civil Service Agency of Majalengka Regency. The purpose of this research is to analyze the influence of career planning, organizational culture and the leadership simultaneously and partially to the effectiveness of employee work. The methods used in this research are descriptive and verification methods. The primary data collection was conducted using census techniques, i.e. the entire population was used as the subject of research. Data sources in this research are primary and secondary data, with data analysis techniques using path analysis. The results showed that career planning conducted by Regional Civil Service Agency of Majalengka Regency is well-perceived; the leadership of the Regional Civil Service Agency of Majalengka Regency is well perceived. That is, the leader of Regional Civil Service Agency of Majalengka Regency has been carrying out his tasks and functions fairly well, especially in order to improve the basic task of Regional Civil Service Agency in providing public services; the organizational culture that makes up the organizational values and norms is well-perceived; Employees at Regional Civil Service Agency of Majalengka Regency are assessed as effective in carrying out their daily work; Career planning is verification a positive and significant influence on the effectiveness of employee work; Leadership proved to have a positive and significant influence on employee work effectiveness; The organizational culture is empirically positive and significant influence on the effectiveness of work; Simultaneously between career planning, leadership and organizational culture affects positively and significantly to the effectiveness of the work.
Genotypic diversity at multiple spatial scales in the foundation marsh species, Spartina alterniflora

Fine-scale variation in both the number and relatedness of genetic individuals can influence a range of ecological and evolutionary processes. However, we often have little information from natural populations regarding the fine-scale distribution of genetic diversity. We quantified multiple metrics of genetic diversity in the widespread, dominant marsh plant Spartina alterniflora across 3 spatial scales in 16 natural marshes in the Florida Panhandle. We also examined correlations between genetic diversity and marsh plant species diversity, along with key environmental variables that may influence both. Most of the variance in S. alterniflora genetic structure was explained by variation within sampling areas across sites. S. alterniflora genetic diversity and marsh plant species diversity increased with spatial scale within sites. In addition, diversity was generally higher on mainland marsh sites compared to discrete marsh islands, consistent with theoretical predictions from island biogeography and population genetics. Multiple metrics of genetic diversity increased with island area and with distance to the mainland. Despite significant correlations between diversity and tidal height, sediment organic content, and sediment porewater salinity, site type (mainland or island) and spatial scale were the best predictors of S. alterniflora genetic and marsh plant species diversity. We show that natural populations of S. alterniflora exhibit significant fine-scale spatial genetic structure, and thus continued loss of habitat could lead to a substantial loss of genetic diversity.
Characterization of digestive enzymes protease and alpha‐amylase activities in the thick‐lipped grey mullet (Chelon labrosus, Risso 1827)

Activities of pepsin, trypsin, chymotrypsin, alpha-amylase and lipase, as well as their optima and stability to pH and temperature, were determined in digestive extracts of thick-lipped grey mullet, Chelon labrosus, of three different sizes: Group 1 (45.2 ± 3.0 g), Group 2 (180.9 ± 4.2 g), and Group 3 (328.5 ± 43.3 g). SDS-PAGE zymograms were also used to assess the role of serine proteases in the digestive tract of C. labrosus. On the other hand, possible changes in the digestive enzyme profile of C. labrosus during development were observed, with a comparatively lower pepsin activity, higher activities of alkaline proteases and alpha-amylase and no lipase activity recorded in pre-adult specimens. It is suggested that these variations are linked to the changes in diet composition with age, moving from a partly carnivorous to a more herbivorous feeding habit.
The counterattack of anti-HER2 small molecule compounds has started

There are two primary types of drugs that target human epidermal growth factor receptor 2 (HER2). One is an antibody-based drug against the HER2 protein and the other is a small molecule compound that inhibits phosphorylation of the HER2 intracellular domain. For many years, antibody-based therapies have been central to the treatment of HER2-positive breast cancer. It is well known that trastuzumab has dramatically changed the treatment for HER2-positive breast cancer and its prognosis (1). Lapatinib, which became available after trastuzumab, also inhibited HER1 phosphorylation and was initially expected to be effective even against HER2negative disease. Therefore, a study including HER2negative advanced recurrent breast cancer was conducted, but the results demonstrated effectiveness only for HER2positive breast cancer (2). The MA.31 trial comparing trastuzumab or lapatinib with taxanes as first-line treatment for HER2-positive advanced recurrence found that lapatinib was inferior to trastuzumab (3). Lapatinib never replaced trastuzumab for first-line treatment. Lapatinib in combination with trastuzumab improved progression free survival (PFS) compared to lapatinib alone, but the improvement was modest so it was positioned as a palliative treatment with few side effects (4). In the NeoALTTO trial using paclitaxel plus either lapatinib or trastuzumab or both for patients with HER2-positive preoperative breast cancer, the pCR (pathological complete response) rate was significantly increased in patients receiving combined trastuzumab and lapatinib (5). However, the parallel ALTTO study did not show a significant improvement in DFS (disease free survival) in postoperative cases and was not used for perioperative treatment (6). The next agent used in combination therapy with trastuzumab was not a small molecule compound, but pertuzumab, which is a similar anti-HER2 antibody that emerged after lapatinib and took its place. The CLEOPATRA study used the combination as a firstline treatment for advanced recurrence of HER2-positive breast cancer and both PFS and overall survival were significantly prolonged (7). Trastuzumab, pertuzumab and taxane combination therapy is the standard regimen for first-line HER2-positive breast cancer. In addition, in the APHINITY study, pertuzumab added to trastuzumab plus a taxane showed improvement compared with conventional trastuzumab and taxane combinations, especially in nodepositive cases (8). This combination is used in perioperative treatment of breast cancer with high HER2-positive recurrence risk. T-DM1, a trastuzumab-based antibody-drug conjugate that was developed around the same time as pertuzumab, showed significantly better PFS and OS than lapatinib plus capecitabine in the EMILIA study (9). This study positioned the small molecule compound lapatinib in a later therapeutic line. In the MARIANNE study, which is a firstline treatment for advanced and recurrent disease, T-DM1 had similar results to trastuzumab plus docetaxel (10). Editorial
Identification of Tuber mycorrhizae using multilocus electrophoresis

This paper reports multilocus electropho- resis for identification of Tuber ectomycorrhizae. The commercial value of some species (e.g., T. magna- tum, T. melanosporum and T. aestivum) makes their identification particularly important at the ectomy- corrhizal stage, for inoculating practices as well as to track the environmental fate of the inoculated spe- cies. The electrophoretic ectomycorrhizal patterns at 4 enzymatic loci, obtained by modifying methods of enzymatic extraction as well as some staining proce- dures, allowed the identification of wild and nursery- inoculated ectomycorrhizal samples of Tuber spp. The results obtained indicate that the electrophoret- ic analysis of gene-enzyme systems is a reliable alter- native method to the conventional morphometric cri- teria of fungal identification. At the same time, it is an useful tool for a rapid and simple identification
"Camouflaging" in Women with Autistic Traits: Measures, Mechanisms, and Mental Health Implications

“Camouflaging” in Women with Autistic Traits: Measures, Mechanisms, and Mental Health Implications Jonathan S. Beck Department of Psychology, BYU Doctor of Philosophy Autistic traits are associated with frequent psychological distress and everyday functional challenges. Some individuals with autistic traits “camouflage” these traits during social interactions by effortfully engaging in “typical” social behaviors. Camouflaging seems to be especially common in autistic girls and women. Emerging evidence proposes a role for camouflaging behaviors in poorer mental health and daily functioning. Furthermore, camouflaging efforts may delay receipt of a proper diagnosis and access to appropriate mental health care. Despite their clinical significance, camouflaging efforts remain difficult to quantify, and the mechanisms and impacts of camouflaging are poorly understood. This study aimed to compare multiple methods of quantifying camouflaging, investigate potential mechanisms of camouflaging, and describe mental health implications of camouflaging behaviors. The sample included 66 women (M age = 25:2 years, SD = 6:4; M IQ = 114, SD = 11) who reported social challenges and scored high on a measure of broad autistic traits. A minority (n = 22) had previously received an autism diagnosis. A majority reported significant anxiety, depression, or suicidality. Camouflaging was quantified using three methods: one self-report questionnaire (CAT-Q), and two discrepancy-based methods that contrasted presentation of autistic traits during the ADOS-2 with measures of less-visible autistic traits (AQ, TASIT-S). Analyses showed that the discrepancy-based measures agreed with each other, but not with the self-report measure of camouflaging. Regression analyses showed camouflaging scores were poorly predicted by age, IQ, performance on executive functioning tasks, and self-reported social cognitive abilities. Regression models including clinician-rated and self-reported autistic traits showed that autistic traits on the SRS-2, and camouflaging efforts on the CAT-Q, modestly but significantly predicted psychological distress and functional challenges. Finally, clinicianadministered and self-report diagnostic measures demonstrated only fair or poorer agreement with each other in this unique sample that includes women with elevated self-reported camouflaging. Results emphasize the clinical significance of the camouflaging construct, which may predict mental health difficulties in individuals with autistic traits better than conventional autism measures. Quantifying camouflaging remains challenging as various proposed measures disagree with each other. Disagreement on diagnostic classification between measures underscores the importance of comprehensive, multi-method assessment of mental health in women who report difficulties fitting into social situations and who may be camouflaging significant autistic traits.
Synthesis, Characterization and Visible Light Induced Photo-Degradation of Acid Orange II Dye in Aqueous Medium using a Novel Synthesized Al2MoZnO7 Nanocomposite

The Al2MoZnO7 (AMZ) nanocomposite had been successfully synthesized via co-precipitation method followed by a low temperature calcinations treatment process. It had been found that such an Al2MoZnO7 nanocomposites exhibits higher photocatalytic activity and stability than pure ZnO towards the aqueous phase degradation of acid orange II dye under visible light (400 nm
Customer Loyalty to Bank Services: The Bibliometric Analysis

Systematisation of literary sources on and approaches to solving the problem of enhancing customer loyalty indicated that scholars had contributed significantly to enriching the scientific research aimed at ensuring the effective long-term consumer interaction. Accordingly, the current paper aims at conducting the bibliometric analysis of publications on customer loyalty to banks institutions. The object of research is the scientific documents published in the biggest abstract database Scopus. The paper follows in the next logical sequence. Firstly, the authors search scientific studies indexed by Scopus database from 2000 to 2019 in the domain of customer loyalty. The document search was conducted in the following areas: the article title, abstract and keywords. Herewith, the combinations of keywords included: bank and customer; bank and loyalty, bank reputation and loyalty; bank confidence and loyalty; bank trust and loyalty; bank and customer; bank and communication strategy. With the irrelevant documents excepted and the duplicate ones eliminated, the determinate sample of documents investigated amounted for 2752 items. Secondly, the selected papers were visualised with VOSviewer software to build the network maps displaying the relationships among the keywords. Thus, the obtained results allowed describing the main directions in the scientific treatise on customer loyalty to banking as well as highlighting the scientific schools interested in exploring the investigated theme. The authors noted that the findings might be the base for future investigation on developing the communication strategies to increase customer loyalty to bank institutions.
Effects of basal drag on subduction dynamics from 2D numerical models

Abstract. Subducting slabs are an important driver of plate motions, yet the relative importance of different forces in governing subduction motions and styles remains incompletely understood. Basal drag has been proposed to be a minor contributor to subduction forcing because of the lack of correlation between plate size and velocity in observed and reconstructed plate motions. Furthermore, in single subduction system models, low basal drag leads to subduction behaviour most consistent with the observation that trench migration velocities are generally low compared to convergence velocities. By contrast, analytical calculations and global mantle flow models indicate basal drag can be substantial. In this study, we revisit this problem by examining the drag at the base of the lithosphere, for a single subduction system, in 2D models with a free trench and composite non-linear rheology. We compare the behaviour of short and long plates for a range of asthenospheric and lithospheric rheologies. We reproduce results from previous modelling studies, including low ratios of trench over plate motions. However, we also find that any combination of asthenosphere and lithosphere viscosity that produces Earth-like subduction behaviour leads to a correlation of velocities with plate size, due to the role of basal drag. By examining Cenozoic plate motion reconstructions, we find that slab age and plate size are positively correlated: higher slab pull for older plates tends to be offset by higher basal drag below these larger plates. This, in part, explains the lack of plate velocity–size correlation in observations, despite the important role of basal drag in the subduction force balance.