Miracle-dz/UniFAR-FTUs huggingface dataset:
A comparative study of two methods to determine acrosome integrity of frozen-thawed boar sperm

Coomassie blue staining has been reported as an effective and inexpensive method for evaluating the acrosome integrity of spermatozoa, though to date its use to evaluate cryopreserved boar sperm has not been reported. Moreover, there is no information concerning the agreement between Coomassie blue staining and fluorescein isothiocyanate conjugated peanut agglutinin and ethidium homodimer (FITC-PNA/EthD-1) methods for assessing sperm acrosome integrity for any species. The current study was performed to determine the efficacy and agreement between Coomassie blue and FITC-PNA/EthD-1 staining methods for evaluating the acrosome integrity of frozen-thawed boar sperm. A total of 25 semen samples were cryopreserved using lactose-egg yolk-based extender and loaded into 0.5 PVC-French straws. Sperm motility and motion characteristics were determined using a computer-assisted sperm analysis system. Sperm viability and plasma membrane integrity were evaluated using the SYBR-14/EthD-1 and hypo-osmotic swelling test, respectively. Acrosome integrity of frozen-thawed boar sperm was evaluated using both FITC-PNA/EthD-1 and Coomassie blue staining to assess the association between sperm acrosome integrity and agreement between these two methods. The average percent acrosome integrity of frozen-thawed boar sperm as determined by FITC-PNA/ EthD-1 and Coomassie blue staining was 48.8 ± 12.6% and 52.6 ± 13.6%, respectively (P>0.05). Interestingly, Coomassie blue staining found a correlation between sperm viability and acrosome integrity (r=0.609, P=0.002), while FITC-PNA/EthD-1 staining did not (P>0.05). However, the acrosome integrity of frozen-thawed boar sperm evaluated by FITC-PNA/ EthD-1 and Coomassie blue staining was significantly correlated (r=0.448, P=0.025, n=25). The Bland-Altman plot determined that this agreement was acceptable. In conclusion, the acrosome integrity of the frozen-thawed boar sperm assessed via Coomassie blue staining was significantly correlated with that obtained via the FITC-PNA/EthD-1 staining method, and the two methods showed good agreement. Moreover, the significant association between the acrosome integrity of frozen-thawed boar sperm determined by Coomassie blue staining with other sperm quality parameters indicates that this is an effective method for assessing the acrosome integrity of frozen-thawed sperm in pigs.
Risk and Survival Analysis from COVID Outbreak Data: Lessons from India

The present analysis is an attempt to provide data-backed evidence around mortality due to COVID-19 in Indian context. We provide a description of the prevailing COVID-19 conditions in India by means of succinct visualisation via a dynamic dashboard and cluster analysis. Building upon this, we performed survival analysis on COVID-19 patients from the state of Karnataka, stratifying the data on the basis of age and gender. The findings of the same have been reported in this paper. To our knowledge, this is the largest retrospective cohort-based survival analysis in Indian context.
Noble gases in three lunar meteorites from Oman

Introduction: During recent years 14 lunar meteorites have been recovered from the Antarctic or from hot deserts. Recently, three small lunar meteorites have been found in Oman: Dhofar 025, an anorthositic regolith breccia, Dhofar 026, an anothositic crystalline melt breccia [1], and Dhofar 081, classified as a feldspatic fragmental highland breccia [2]. The first two meteorites were found about 20 km apart from each other. The find location of Dhofar 081 is more than 200 km away from the other two lunar meteorites. We have measured the noble gases in samples of all three meteorites to obtain information on a possible pairing, on the trapped noble gas component and on the irradiation history of this lunar material. Measured concentrations and isotopic composition of noble gases in bulk samples as well as the sum of temperature steps of a Dhofar 025 sample are given in Tab.1.
Work Motivation and Job Performance of Cataloguers in Academic Libraries in South-West Nigeria

1 Department of Information Resources Management Babcock University Ilishan-Remo, Ogun State, Nigeria. Corresponding author’s E-mail: ujprecious@yahoo.com, j.nwabugwu@nials.edu. ng 2 Department of Information Resources Management, Babcock University Ilishan-Remo, Ogun State, Nigeria E-mail: unegbuv@babcock.edu. ng 3 Department of Information Resources Management, Babcock University Ilishan-Remo, Ogun State, Nigeria E-mail: owolabir@babcock.edu. ng
Antitumor Activity of Small Activating RNAs Induced PAWR Gene Activation in Human Bladder Cancer Cells

Small double-stranded RNAs (dsRNAs) have been proved to effectively up-regulate the expression of particular genes by targeting their promoters. These small dsRNAs were also termed small activating RNAs (saRNAs). We previously reported that several small double-stranded RNAs (dsRNAs) targeting the PRKC apoptosis WT1 regulator (PAWR) promoter can up-regulate PAWR gene expression effectively in human cancer cells. The present study was conducted to evaluate the antitumor potential of PAWR gene induction by these saRNAs in bladder cancer. Promisingly, we found that up-regulation of PAWR by saRNA inhibited the growth of bladder cancer cells by inducing cell apoptosis and cell cycle arrest which was related to inhibition of anti‑apoptotic protein Bcl-2 and inactivation of the NF-κB and Akt pathways. The activation of the caspase cascade and the regulation of cell cycle related proteins also supported the efficacy of the treatment. Moreover, our study also showed that these saRNAs cooperated with cisplatin in the inhibition of bladder cancer cells. Overall, these data suggest that activation of PAWR by saRNA may have a therapeutic benefit for bladder cancer.
Bioavailability of 2, 4, 6-Trinitrotoluene (TNT) to Earthworms in Three Different Types of Soils in China

ABSTRACT To study the effects of aging time (the length of time when contaminants are sequestered in soil) and soil properties on TNT bioavailability in soil, earthworms (Eisenia fetida) were exposed to three types of soils (fluvo-aquic soil, loessal soil, and black soil) contaminated by TNT for 7, 14, 21, 28, 35, and 42 days. The Earthworm-Soil Accumulation Factor (ESAF) of TNT and soil properties were analyzed. The ESAFs in black soil were significantly lower than those in fluvo-aquic soil and loessal soil (P < 0.05). In loessal soils, the ESAF increased with aging time, while that in black soils decreased. The ESAF of TNT had a significantly negative correlation with soil organic matter content, clay contents, and cation exchange capacity, which were the main factors affecting the TNT bioavailability in soils (P < 0.01). There was more quartz and feldspar in black soil, as well as more particles and micropores on the surface, which resulted in the easy adsorption and lower bioavailability of TNT. In conclusion, TNT bioavailability in soils is affected by aging time, soil physical and chemical properties, and mineral and surface properties, which must be considered when biotreatment for TNT in soils is applied.
TRRM_A_264872 23..28

Department of Urology, College of Medicine, Majmaah University, Al-Majmaah 11952, Saudi Arabia Purpose: In this modern era, organ transplantation has become an important treatment method for certain diseases. Doctors and allied health professionals play important roles in continuing its advocacy and sharing knowledge within the community; thus, educating the public on organ donation is paramount. The present study aimed to understand the knowledge, attitude, and willingness toward organ donation of medical and health sciences students. Materials and Methods: We conducted a cross-sectional questionnaire-based study from January to March 2020. The pretested questionnaire was prepared on Google Forms, and the link was shared with 467 students graduating in medicine, dentistry, nursing, physiotherapy, and paramedical studies to analyze their knowledge, attitudes, and willingness towards organ donation. Of 467 students, 425 students provided complete answers and were included in data analysis. Results: We found that knowledge scores were uniformly low among students in all specialties except for those studying medicine and physiotherapy (p = 0.001). Moreover, female students scored higher than male students in all the three domains of knowledge, attitude, and willingness toward organ donation, and such was statistically significant (p = 0.001). Conclusion: Since final-year medical and health sciences students will soon graduate and join their respective professions, we recommend the integration of the topic of organ donation into their final-year curriculum to provide them with adequate knowledge so that they can provide proper guidance to the general public. Similarly, the advocacy in promoting organ donation should be increased through the use of appropriate mediums to change the attitudes and enhance the willingness of people.
STUDY OF FIRM VALUE BASED ON CHARACTERISTIC COMPANY: STATE OWNED ENTERPRISE LISTED INDONESIAN STOCK EXCHANGE

This research aims to determine the effect of company characteristics proxied by leverage, profitability and firm size on firm value as measured by Price to Book Value (PBV) in state-owned enterprise listed on the Indonesia Stock Exchange with the 2013 study period -2017. In this study using a total of 65 samples from 13 state-owned enterprises that meet the criteria. The sampling technique used in this study is purposive sampling method. The statistical method used to test this research is a multiple regression model.The results of this study indicate that the influence of the characteristics of companies that are proxied with leverage and profitability has positive effect and significant on the firm value as measured by Price to Book Value (PBV), but firm size has negative effect not significant on the firm value.
Microfinance Access and Women Empowerment in the Far North Region of Cameroon

The objective of our paper is to analyze the effects of Microfinance access to women empowerment. The work aims to measure the contribution of Microfinance on women entrepreneurship in the Diamare Division of the Far North Region in Cameroon. To achieve these results, we used data collected from the population established data from Ecam 4. Using the stata 14 to captured the induced effects of this instrument , we used the binary logistic regression model to determine female access to Microfinance. on the results, we recommend that the state through different political, can put in place different instruments to encourage financial services by providing a regulatory system assistance with paying salaries and utility bills. Microfinance is a way forward for women empowerment in Cameroon and particular the Far North region, considered as an economically depressed region by the Cameroonian state. But to achieve this, the government should create an enabling environment in which banks are free to pursue the innovations necessary to reach low-income consumers while realizing profits.
ASP ($\mathcal A \mathcal C$): Answer Set Programming with Algebraic Constraints

Abstract Weighted Logic is a powerful tool for the specification of calculations over semirings that depend on qualitative information. Using a novel combination of Weighted Logic and Here-and-There (HT) Logic, in which this dependence is based on intuitionistic grounds, we introduce Answer Set Programming with Algebraic Constraints (ASP($\mathcal A \mathcal C$)), where rules may contain constraints that compare semiring values to weighted formula evaluations. Such constraints provide streamlined access to a manifold of constructs available in ASP, like aggregates, choice constraints, and arithmetic operators. They extend some of them and provide a generic framework for defining programs with algebraic computation, which can be fruitfully used e.g. for provenance semantics of datalog programs. While undecidable in general, expressive fragments of ASP($\mathcal A \mathcal C$) can be exploited for effective problem solving in a rich framework.
Determinantal point process models and statistical inference: Extended version

Statistical models and methods for determinantal point processes (DPPs) seem largely unexplored. We demonstrate that DPPs provide useful models for the description of spatial point pattern datasets where nearby points repel each other. Such data are usually modelled by Gibbs point processes, where the likelihood and moment expressions are intractable and simulations are time consuming. We exploit the appealing probabilistic properties of DPPs to develop parametric models, where the likelihood and moment expressions can be easily evaluated and realizations can be quickly simulated. We discuss how statistical inference is conducted using the likelihood or moment properties of DPP models, and we provide freely available software for simulation and statistical inference.
Why Not Explain? Effects of Explanations on Human Perceptions of Autonomous Driving

Autonomous vehicles (AVs) have the potential to change the way we commute, travel, and transport our goods. The deployment of AVs in society, however, requires that people understand, accept, and trust them. Intelligible explanations can help different AV stakeholders to assess AVs' behaviours, and in turn, increase their confidence and foster trust. In a user study (N = 101), we examined different explanation types (based on investigatory queries) provided by an AV and their effect on people using the trust determinant factors. Our quantitative and qualitative analysis shows that explanations with causal attributions improved task performance and understanding when assessing driving events but did not directly improve perceived trust. This underlines the potential need for additional measures and research to enhance trust in AVs.
CMAR_A_266653 9057..9066

1Department of Hepatobiliary and Pancreatic Surgery, The Second Affiliated Hospital of Guilin Medical University, Guilin 541199, Guangxi, People’s Republic of China; 2Laboratory of Hepatobiliary and Pancreatic Surgery, Affiliated Hospital of Guilin Medical University, Guilin 541001, Guangxi, People’s Republic of China; 3Second Clinical Medical College, Guangxi Medical University, Nanning 530021, Guangxi, People’s Republic of China; 4Science Experiment Center, Guangxi Medical University, Nanning, Guangxi, 530021, People’s Republic of China; 5Department of Pathology, Guilin Medical University, Guilin 541001, Guangxi, People’s Republic of China
Computación y Sistemas, Vol. 22, No. 4, 2018

Social media platforms have been witnessing a significant increase in posts written in the Tunisian dialect since the uprising in Tunisia at the end of 2010. Most of the posted tweets or comments reflect the impressions of the Tunisian public towards social, economical and political major events. These opinions have been tracked, analyzed and evaluated through sentiment analysis systems. In the current study, we investigate the impact of several preprocessing techniques on sentiment analysis using two sentiment classification models: Supervised and lexicon-based. These models were trained on three Tunisian datasets of different sizes and multiple domains. Our results emphasize the positive impact of preprocessing phase on the evaluation measures of both sentiment classifiers as the baseline was significantly outperformed when stemming, emoji recognition and negation detection tasks were applied. Moreover, integrating named entities with these tasks enhanced the lexicon-based classification performance in all datasets and that of the supervised model in medium and small sized datasets.
New covalent ceramics: MgSiN2

The ternary nitride MgSiN2 crystallizes in a diamond-like structure with a band gap of 4.8 eV. These characteristics make the compd. promising for a variety of applications. Recently we succeeded in prepg. fully dense ceramics by sintering at 1550 DegC. Phase compn. , chem. properties and the mech. properties of the as-prepd. ceramics are described. The ceramics are resistant to oxidn. in air at least up to 920 DegC. The thermal cond. at room temp. has been found to be 20 W/m.K. A considerable improvement of the thermal cond. is expected when improved processing conditions, well within reach, are realized. A reasonable strength of 270 MPa and a fairly good fracture toughness of about 4.3 MPa.m1/2 were obtained. A hardness of about 15 GPa and a Young's modulus of 235 GPa have been measured. These new ceramics show that it is still possible to find improved materials as compared to the usual oxide and non-oxide ceramics. [on SciFinder (R)]
Low-dose total body irradiation facilitates antitumoral Th1 immune responses

CD4+ T helper cells are capable of mediating long-term antitumoral immune responses. We developed a combined immunotherapy (COMBO) using tumor antigen-specific T helper 1 cells (Tag-Th1), dual PD-L1/LAG-3 immune checkpoint blockade, and a low-dose total body irradiation (TBI) of 2 Gy, that was highly efficient in controlling the tumor burden of non-immunogenic RIP1-Tag2 mice with late-stage endogenous pancreatic islet carcinomas. In this study, we aimed to explore the impact of 2 Gy TBI on the treatment efficacy and the underlying mechanisms to boost CD4+ T cell-based immunotherapies. Methods: Heavily progressed RIP1-Tag2 mice underwent COMBO treatment and their survival was compared to a cohort without 2 Gy TBI. Positron emission tomography/computed tomography (PET/CT) with radiolabeled anti-CD3 monoclonal antibodies and flow cytometry were applied to investigate 2 Gy TBI-induced alterations in the biodistribution of endogenous T cells of healthy C3H mice. Migration and homing properties of Cy5-labeled adoptive Tag-Th1 cells were monitored by optical imaging and flow cytometric analyses in C3H and tumor-bearing RIP1-Tag2 mice. Splenectomy or sham-surgery of late-stage RIP1-Tag2 mice was performed before onset of COMBO treatment to elucidate the impact of the spleen on the therapy response. Results: First, we determined a significant longer survival of RIP1-Tag2 mice and an increased CD4+ T cell tumor infiltrate when 2 Gy TBI was applied in addition to Tag-Th1 cell PD-L1/LAG-3 treatment. In non-tumor-bearing C3H mice, TBI induced a moderate host lymphodepletion and a tumor antigen-independent accumulation of Tag-Th1 cells in lymphoid and non-lymphoid organs. In RIP1-Tag2, we found increased numbers of effector memory-like Tag-Th1 and endogenous CD4+ T cells in the pancreatic tumor tissue after TBI, accompanied by a tumor-specific Th1-driven immune response. Furthermore, the spleen negatively regulated T cell effector function by upregulation PD-1/LAG-3/TIM-3 immune checkpoints, providing a further rationale for this combined treatment approach. Conclusion: Low-dose TBI represents a powerful tool to foster CD4+ T cell-based cancer immunotherapies by favoring Th1-driven antitumoral immunity. As TBI is a clinically approved and well-established technique it might be an ideal addition for adoptive cell therapy with CD4+ T cells in the clinical setting.
The Influence of Foot Position on Standing Balance on an Unstable Base of Support

The purpose of this study was to compare the balance ability at different foot positions using K A T 2000 (Berg, Inc, vista, CA.1994). Thirty (male 15, female 15) normal subjects participated in this study. All subjects were tested at a one leg position or a two leg position that were toe-in 25 ̊, toe-out 25 ̊, and 45 ̊. The starting position was where the subject crossed their arms across the chest and flexed knees slightily. The results of each test were displayed on a screen in a score format, which indicated balance index. These collected data were analyzed by using one way ANOVA, and t-test. The results of this study were as follows: When changing the angle of the foot in the one-foot and two-foot standing positions, there was no statistically significant difference, but the balance performance with the foot rotated by 25 ̊ was better than that with the foot rotated by 45 ̊. When changing the direction of the foot in the one-foot and two-foot standing positions, there was no statistically significant difference, but the balance performance with the foot rotated laterally was better except for the case when the foot was medially rotated by 25 ̊ in the right-foot static standing position. When the feet were medially rotated by 25 ̊ in the two-foot static standing position, and were medially rotated by 25 ̊ and 45 ̊ in the one-foot static standing position, the balance performance of females was better than that of males. In this study, it was found that the balance performance of the subjects changed when the position of the foot was shifted on an unstable base of support. However, there was little correlation between balance performance and the height, weight and foot length of the subjects. It is necessary to conduct a follow-up study targeting various age groups and those with various diseases using an unstable platform or applying different physical or visual conditions, such as the length of the legs. Physical therapists need to consider the position of the foot in clinical settings for a better balance training or assessment.
DMSO_A_252492 2719..2727

*These authors contributed equally to this work Purpose: This study aimed to identify the prevalence and gender differences of metabolic syndrome in young new-onset ketosis-prone type 2 diabetic (KPT2D) individuals. Patients and Methods: A retrospective study was conducted in Shanghai Xin Hua Hospital from 2007 to 2019. A total of 304 patients from 12 to 40 years of age with newly diagnosed diabetes presenting with ketosis were analyzed. The clinical features and laboratory results of KPT2D and type 1 diabetic (T1D) individuals were compared. Prevalence and gender differences of metabolic syndrome in the KPT2D subjects were analyzed. Results: The prevalence of metabolic syndrome (P < 0.0001) was significantly higher in young KPT2D than T1D subjects. The prevalence of high blood pressure (P < 0.0001), central obesity (P < 0.0001), low plasma HDL-C concentration (P = 0.045), and hypertriglyceridemia (P < 0.0001) was elevated in the KPT2D subjects compared with T1D. Male predominance (89%) was presented in the KPT2D subjects. The prevalence of metabolic syndrome (P = 0.0002) was significantly higher in young male than female KPT2D subjects. The presence of central obesity (P < 0.0001) and high blood pressure (P =0.03) was higher in male KPT2D subjects than female. The presence of serum triglyceride concentrations ≥ 2.3mmol/L was significantly higher (P = 0.011) in male KPT2D subjects than female. Conclusion: Significantly higher prevalence of metabolic syndrome in young KPT2D patients compared with T1D patients could be an important reference for diabetic differential diagnosis. KPT2D presented a higher predominance in young males, who had higher prevalence of metabolic syndrome than young females.