Miracle-dz/UniFAR-FTUs huggingface dataset:
Regulation of Mesenchymal Differentiation Potentials in the avian Neural Crest

The neural crest (NC) is a transitory multipotent structure of the vertebrate embryo. The cephalic NC (CNC), not the trunk NC (TNC), gives rise to mesenchymal cell types (contributing to craniofacial skeleton, dermis and adipose tissue). This capacity of the CNC has been linked to the absence of Hox gene expression in the most rostral region of the embryo. However, TNC cells do have mesenchymal potentialities, although in a dormant state in vivo, but which can be disclosed after NC in vitro culture. The molecular mechanisms that regulate mesenchymal potentials of the NC cells along the rostral-caudal axis are still elusive. Here, we have used the avian embryo model to investigate the possible influence on NC mesenchymal fate, of Hox and Six transcription factor genes. On the one hand, in vivo and in vitro culture analyses show that Six1 gene is expressed in mesenchymal cell populations derived from both cranial NC and mesoderm, suggesting a role for Six1 in muscle-skeletal development in the head. On the other hand, we have tested the hypothesis of an inhibitory action of Hox genes on NC cell mesenchymal differentiation using NC in vitro cultures. In CNC cells, we found that ectopic expression of Hoxa2 strongly reduces the production of osteoblasts, while neural and melanocytic phenotypes are unaffected. In the cultured CNT cells, overexpression of Hoxa2 results in largely impaired differentiation into bone cells, chondrocytes and adipocytes, whereas other NC derivatives are unchanged. These results suggest that mesenchymal potentials of the CNC and TNC are controlled, at least in part, via a common mechanism that involves inhibition of Hoxa2 gene activity.
Development of Problem-Based Mathematical Learning Device on Problem Based Learning (PBL) Models by Using GeoGebra Aids to Improve the Problem Solving Skill of the Students in VIII Class of Junior High School (Preliminary Research)

Students’ low ability in mathematical problem solving can still be found by the researcher in the field. This can be seen in the implementation of learning at school, students are not get used to solved the problem appropriately. Some problem solving indicators are not found during students solved the problem. Students’ mathematical learning ability can be improved by using learning device based on PBL by using GeoGebra aids. The purpose of this research is to reveal the process and the result of PBL learning device development by using GeoGebra aids in improving students’ mathematical problem solving skill. GeoGebra is software aimed to solve mathematics problem. One of them is to create graphic. This is a development research. The research model is Plomp model which consists of three phases, namely, preliminary research, development or prototyping phase, and assessment phase. In this part, the researchers only discuss about preliminary research. Researchers employ some instruments such as: student questionnaire, teacher interview guideline, field note, and preliminary test question sheet. Data analysis result shows that 1) students’ mathematical problem solving is still low, 2) LKPD used by the students has yet be able to facilitate them to improve their problem solving skill, 3) students’ are less engaged in the learning process, 4) students like LKPD that is easy to understand, has color, and has clear pictures.
Marketing Strategy of Madilog Coffee Shop using Influencers through Instagram Social Media

Marketing Strategy of Madilog Coffee Shop using Influencers through Instagram Social Media (Case Study at Madilog Coffee Shop). This type of research uses a qualitative research design. The number of informants in this study amounted to 4 people (1 Owner and 3 Visitors). Samples will be obtained by using a purposive sampling technique. Data collection techniques can be done by way of interviews (interviews), and observations (observations), and a combination of the three, directly from respondents selected as a sample, which includes data on the identity of respondents. Based on the results obtained using qualitative analysis, it can be concluded in this study that the reason why the marketing strategy of Madilog Coffee Shop Marketing Using Influencers Through Instagram Social Media switches from conventional ways to Instagram marketing, namely, first because of technological advances using mobile phones, consumers are more often using Instagram social media, secondly by using social media marketing especially Instagram can further reduce marketing costs, Thirdly by utilizing influencers to increase marketing on Instagram, and have a positive impact on the progress of Madilog Coffee Shop using Influencers through Instagram Social Media, finally the role of place variables / place in the marketing mix can make Madilog Coffee Shop Marketing Strategies use Influencers through Instagram Social Media to come back to Madilog Coffee Shop Marketing Strategies using This Influencer Through Social Media Instagram gives and places an attractive place for consumers and the price is also in accordance with the prices of students. The place according to the researchers is less strategic but with advances in technology and promotion strategies that Madilog Coffee Shop.
Pyrolysis Kinetic Parameters of Omari Oil Shale Using Thermogravimetric Analysis

Oil shale is one of the alternative energies and fuel solutions in Jordan because of the scarcity of conventional sources, such as petroleum, coal, and gas. Oil from oil shale reservoirs can be produced commercially by pyrolysis technology. To optimize the process, mechanisms and rates of reactions need to be investigated. Omari oil shale formation in Jordan was selected as a case study, for which no kinetic models are available in the literature. Oil shale was analyzed using the Fischer assay method, proximate analysis (moisture, volatile, and ash), gross calorific value, elemental analysis (CHNS), and X-ray fluorescence (XRF) measurements. Non-isothermal thermogravimetric analysis was applied to study the kinetic parameters (activation energy and frequency factor) at four selected heating rates (5, 10, 15, and 20 °C/min). When oil shale was heated from room temperature to 1100 °C, the weight loss profile exhibited three different zones: drying (devolatilization), pyrolysis, and mineral decomposition. For each zone, the kinetic parameters were calculated using three selected methods: integral, temperature integral approximation, and direct Arrhenius plot. Furthermore, the activation energy in the pyrolysis zone was 112–116 kJ/mol, while the frequency factor was 2.0 × 107 − 1.5 × 109 min−1. Moreover, the heating rate has a directly proportional relationship with the rate constant at each zone. The three different methods gave comparable results for the kinetic parameters with a higher coefficient of determination (R2) for the integral and temperature integral approximation compared with the direct Arrhenius plot. The determined kinetic parameters for Omari formation can be employed in developing pyrolysis reactor models.
Colina e metionina+cistina digestível para codornas em fase de postura

Entre os nutrientes essenciais que influenciam diretamente no desempenho das aves, destaca-se a metionina, primeiro aminoacido limitante para aves quando sao utilizadas dietas a base de milho e farelo de soja. Assim, o adequado conhecimento da sua exigencia e possiveis interacoes com outros nutrientes no organismo e necessario. Assim, objetivou-se avaliar a relacao entre colina e metionina+cistina digestivel em racoes para codornas em fase de postura, sobre as caracteristicas de desempenho, qualidade de ovos e excrecao de nitrogenio (N). O experimento foi desenvolvido em esquema fatorial 4x2, considerando quatro niveis de colina (0,0; 0,042; 0,084 e 0,126%) e dois niveis de metionina (0,857% e 0,685%,), totalizando oito tratamentos com cinco repeticoes e sete aves em cada parcela, distribuidas em delineamento inteiramente casualizado. Os parâmetros avaliados foram: consumo de racao, percentual de postura, conversao alimentar (CA) por duzia e massa de ovos, peso do ovo, unidade Haugh, espessura de casca, gravidade especifica, percentual de casca, gema e albumen e N excretado. Nao houve interacao entre os fatores sobre nenhuma das variaveis avaliadas, exceto em relacao ao peso das codornas (P˂0,01). O nivel de 0,857% de metionina + cistina digestivel e a maior inclusao de colina melhoraram o peso dos ovos (P=0,03), a CA/massa de ovos (P=0,02) e o percentual de gema (P˂0,01). Em contrapartida, houve reducao linear no percentual do albumen (P˂0,01) com o aumento da inclusao de colina na dieta. Houve resposta quadratica dos niveis de colina sobre o percentual de casca dos ovos, estimando 0,047% de colina na racao. A gravidade especifica dos ovos reduziu linearmente (P˂0,01), com a inclusao de colina na dieta. A excrecao de nitrogenio apresentou comportamento quadratico inverso (P=0,04), no qual o nivel otimo de 0,126 % de colina proporcionou reducao de N para o ambiente em 1,55%, se comparado com o tratamento sem colina. Conclui-se que para melhor peso dos ovos, CA/massa de ovos, percentual de gema e reducao de N fecal de codornas japonesas em fase de postura, o nivel indicado de metionina + cistina digestivel e de 0,857% e colina de 0,126%.
Analysis of archaic human haplotypes suggest 5-hmC to act as epigenetic guide for meiotic point recombination

Meiotic “point recombination” refers to homologue recombination events affecting only individual SNPs. Driven mostly by gene conversion, it is common process that allows for a gradual adaptation and maturation of haplotypes during genetic evolution. In contrast to crossover recombination it is not tied to predetermined recombination sites and therefore assumed to occur largely randomly. Our analysis of archaic human haplotypes however revealed striking differences in the local point recombination rate. A linkage-study of 1.9 million SNPs defined by the sequence of denisovan hominids revealed low rates in introns and quiescent intergenic regions but high rates in splice sites, exons, 5’- and 3’-UTRs, and CpG islands. Correlations with ChIP-Seq tracks from ENCODE and other public sources identified a number of epigenetic modifications, that associated directly with these recombination events. A particularly tight association was observed for 5-hydroxymethylcytosine marks (5hmC). The mark was enriched in virtually all of the functional regions associated with elevated point recombination rates, including CpG islands and ‘poised’ bivalent regions. As intermediate of oxidative demethylation, 5hmC is also a marker of recently opened gene loci. The data, thus, supports a model of ‘guided’ evolution, in which point recombination is directed by 5hmC marks towards the functionally relevant regions.
Political party membership and personality characteristics in the Czech Republic (2005)

This paper examines the relationship between Big Five personality dimensions and membership in political parties in the Czech Republic. A total of 194 members from eight major Czech political parties filled out the NEO Five-Factor Inventory to assess the Big Five personality dimensions. The mean scores of the respondents from each party were compared to the scores of a sample of the general Czech population. The members of three right-wing parties scored lower in agreeableness and the members of one left-wing party were higher in agreeableness than the general population, which is consistent with results from other countries. The Greens scored higher in openness than the general population, which is consistent with results from Germany. Members of former governing parties, which had long been out of power, scored lower in neuroticism than the general population.
Analysis of the Multi-Steps Package (MSP) for Series-Connected SiC-MOSFETs

In this paper, a multi-step packaging (MSP) concept for series-connected SiC-MOSFETs is analyzed. The parasitic capacitance generated by the dielectric isolation of each device in the stack has a significant impact on the dynamic behavior of SiC devices, which impacts the voltage-sharing performances. The study performed in this work reveals that the parasitic capacitance network introduced by the classical planar packaging unbalances the voltage across the series-connected SiC-MOSFETs. Therefore, a new drain-source parasitic capacitance network configuration provided by the MSP is proposed in order to improve the voltage balancing across the series-connected devices. The concept is introduced and analyzed thanks to equivalent models and time domain simulations. To verify the analysis, the voltage sharing between four series-connected 1.2 kV SiC MOSFETs is tested in a double pulse test setup. The experimental results confirm that the MSP has a better performance than the classical one in terms of voltage sharing. Furthermore, the proposed investigation shows that the MSP increases the middle point dv/dt of the switching cell. Sensitive analysis and thermal management considerations are also discussed in order to clarify the MSP limitations and indicate the ways to optimize the MSP from a thermal point of view.
Host specificity of Avipox viruses: an experimental study with field isolates of fowlpox, pigeonpox and duckpox viruses

A study was conducted to determine the host specificity of field isolates of fowl pox virus (FPV), pigeon pox virus (PPV) and duck pox virus (DPV) by giving cross infection. During inoculation of fowl pox virus (FPV) in embryonated chicken eggs, and duck pox virus (DPV) in embryonated duck eggs showed PCR positive during the first passage itself. Inoculation of pigeonpox and duckpox viruses in embryonated chicken eggs required 2–3 initial passages to get the positive results. In the experimental study, all the chicks inoculated with FPV developed pox lesions within 7–9 days post infection. Similarly, all the pigeons inoculated with PPV developed pox lesions within 5–9 days. Likewise, all the ducklings inoculated with DPV developed pox lesions within 5–6 days. In cross infection study when FPV, PPV and DPV were inoculated in heterologous hosts no lesions were developed. Histopathological examination of the scab samples of infected birds revealed intracytoplasmic eosinophilic inclusion bodies. Among the visceral organs the lungs showed congestion and haemorrhages with proliferation of lymphoid cells around the bronchioles, the heart showed capillary congestion between the myofibrils, hydropic degeneration and fatty changes in the liver and renal tubular epithelium. The scab samples of infected birds showed positive results for APV by PCR; but the biopsy samples collected from the inoculated site of the heterologous hosts showed PCR negative. It was concluded that field isolates of fowl pox virus (FPV), pigeon pox virus (PPV) and duck pox virus (DPV) exhibited host specificity and did not produce cross infection in heterologous hosts.
A Cost-Benefit Methodology for Selecting Analytical Reinforced Concrete Corrosion Onset Models

This work focuses on predicting corrosion onset induced by concrete carbonation or chloride ingress when using analytical predictive models. The paper proposes a procedure that helps building and infrastructure managers to select an appropriate model depending on the available information and the means granted to auscultation campaigns. The approach proposed combines the costs of input parameters, their relative importance, the benefits brought through obtaining parameters, and the maintenance strategy of the manager. Costs represent the intellectual investment to obtain parameters. This encompasses the time spent to obtain and analyze a result and the required expertise. Relative importance and benefits are obtained from sensitivity analysis. The effect of the maintenance strategy is introduced through a scalar called efficiency of the model. The proposed methodology is illustrated with two case studies where it is supposed that more or less extended information is available. Three concrete qualities are also considered in the case studies. The results highlight that the available data and concrete type have significant impacts on the selection of the most appropriate model.
Chemical monitoring of baru (dipteryx alata vog.) pulp fermented beverage

The Baru (Dipteryx alata Vog.) tree, from the Leguminosae family, disseminated mainly in the brazilian cerrado, is part of the group of native species used by the regional population as a source of family income (Sano et al., 2004). It is one of the most promising species for cultivation due to its multiple uses, including food, timber, medicinal, industrial, landscape and recovery of degraded areas.
Childcare in Lithuania and Belarus: how gendered is parenting in Eastern European countries?

ABSTRACT Research shows that even though the time women and men spend on housework has slowly converged in recent decades, the time mothers and fathers invest in childcare has not changed as much. This paper aims to contribute to the literature on childcare by focusing on the two Eastern European countries of Lithuania and Belarus, which took very different development paths after seceding from the Soviet Union in 1990. For our analysis, we use two recent datasets: the Families and Inequalities Survey from 2019 for Lithuania, and the Generations and Gender Survey 2020 Belarus Wave 1 from 2017. The analytic sample consists of 2114 mothers and fathers born between 1970 and 1984 with children under age 14. Our results reveal that in both Lithuania and Belarus, mothers perform more childcare tasks than fathers, and that, however, gendered parenting is more prominent in Lithuania than in Belarus.
The Role and Potential of Information Technology in Agricultural Development

Rural people are migrating towards urban areas to search the better opportunities for last couple of decades. Basic infrastructure facilities available in rural area are very less. Due to the lack of development and opportunities rural community will migrate to urban areas in search of jobs. This causes decline in economy of rural areas. Special focus has to be given for rural development which can enhance economy, social status and life style and living standards of the rural people. The task is to find different ways of using the ICT to assist development in activity in rural to improve living standard and achieve a specific goal or objective Agriculture is one of the major components of economy and plays a key role in the nation development. But improvements in agricultural sector are uneven and disappointing. ICT has the potential to address the challenges, however use of the technology in agricultural and rural areas is very slow. Purpose of the proposed study is to review the opportunities, potential and contribution of ICT in agricultural sector Keywords— Agriculture, information and communication technology,
“Doing what it takes to keep the school open”: The philanthropic networks of progressive charter schools

Researchers have demonstrated how venture philanthropic networks advance the growth of charter schools underpinned by market tenets. However, little remains known about how progressive charter schools mobilize financial support when most funding from philanthropic networks flows to market-oriented charters. This qualitative study examines how three progressive charter schools in New York City mobilized financial support, the extent to which charters’ financial supporters operated in a networked context, and the extent to which charters’ resource mobilization activities reflected their founding progressive tenets. Findings reveal that the focal charters incorporated market logic when cultivating financial support networks. In doing so, schools endeavored to secure their own resource advantages while reinforcing resource inequities across New York City’s unequal educational landscape, hence undermining the equity and community responsibility dimensions of their progressive missions.
Engaging participants in qualitative research: methodological reflections on studying active older lives in Scotland and Australia

ABSTRACT Deliberations on methodology in qualitative research have typically offered guidance for increasing involvement by subjects or focus on the reasons why people choose not to take part in the research. This paper provides a different contribution to advancing knowledge and practice in qualitative methodologies. It examines the reasons why people choose to participate in qualitative research. Drawing together our reflections on three research projects with older athletes in Australia and Scotland, the paper examines: the importance of shared insider experience and physical capital by the researchers and participants alike, participant empowerment and enthusiasm to share their passion as older athletes and; the opportunity for the research to counter perceptions of invisibility – of leisure interests, older people and active older women more particularly as key factors in engaging participants in the research process. Specifically, we link the sociological concept of capital and the notion of the gambit to qualitative studies in sport, health and leisure. As a sociological reflection on both the design and methods of qualitative research and the subjective experiences of our participants, the research has wider significance and application to critical qualitative methodologies more broadly and investigations of older people’s leisure experiences more specifically.
Chornobyl radiation—congenital anomalies: A persisting dilemma

We report population prevalence rates of neural tube defects (NDT) and microcephaly (MIC) as well as levels of incorporated Cs137 by pregnant women in two areas of the Rivne Province of Ukraine, a northern half (Polissia) polluted by Chornobyl radiation and not‐Polissia areas. Monitoring of congenital malformations was conducted with adherence to methods adopted by a European surveillance network (EUROCAT). Incorporated Cs137 (Bq/kg) by pregnant women residing in the Polissia and not‐Polissia areas were obtained concurrently with prenatal ultrasound examinations. In Polissia, the incorporated Cs137 levels by pregnant women as well as the prevalence rates of NDTs and MIC are significantly higher than in not‐Polissia. In Polissia, the prevalence rates of NDTs and MIC are among the highest in Europe. The debate concerning the teratogenic impact of chronic exposures to low levels of ionizing radiation was re‐ignited by our 2010 report. Health agencies uphold the notion that exposure to Chornobyl radiation levels are too low to be teratogenic, which is inconsistent with our observations. Further investigations in Rivne by international teams can, we believe, contribute facts to the ongoing debate. Our monitoring system, experience and data can facilitate concurrent investigations of teratogenic risks from exposures to other sources of ionizing radiation, alcohol, folate, and zinc deficiencies, among other risk factors. Study of genomic impacts can likewise be undertaken.
Status of Invasive Plant Species in the Dry Savanna Grasslands of Rajiv Gandhi Orang National Park, Assam

The grasslands in the floodplains of North East India are known for its faunal diversity with special reference to its mega herbivores. This ecosystem is presently under threat with the invasion of various plant species. We studied current status of invasive plant species in dry savanna grassland of Rajiv Gandhi Orang National Park, Assam. Four invasive plants species have been recorded from the study area viz. Ageratum conyzoides (L.), Chromolaena odorata (L.) R. M. King & H. Rob. , Mikania micrantha Kunth, and Mimosa diplotricha Sauvalle. Among the invasive plants, Chromolaena had the highest density (261 individuals ha-1) and IVI (7.88) followed by that of Mikania and Mimosa. Chromolaena was the most frequent species, while Ageratum was the least recorded plant. The status assessment of invasive plant species in this very important protected grassland ecosystem in North East India will be helpful in making a sound management protocol for the invasive plant species.