Miracle-dz/UniFAR-FTUs huggingface dataset:
Effect of Silica Nanoparticles On Flexural Strength And Surface Hardness Of Heat Polymerized Acrylic Resin.

Statement of problem. Various studies are present to increase the strength and surface hardness of heat polymerized acrylic resin by addition of material or surface treatments. The present study to evaluate an effect of silica nanoparticles on flexural strength and surface hardness of heat polymerized acrylic resin. Purpose. The purpose of this study was effect of silica nanoparticles, incorporated into Polymethyl Methacrylate, on flexural strength and surface hardness. The present study compared the effect of silanated and non silanated silica nanoparticles on the flexural strength and surface hardness of heat polymerized acrylic resin. Material and Methods. A total of 270 acrylic bars were fabricated, in two batches of 135 each, for testing flexural strength by universal testing machine and surface hardness determined using a digital micro Vickers hardness tester. The control group and subgroups had a sample size of 15 each with varied concentrations of nanoparticles by weight. The fabricated samples were tested for flexural strength and surface hardness. Results. Flexural strength was highest for PMMA (Polymethyl methacrylate) with 0.5% silanated silica nano particles as fillers. In both the groups, the flexural strength decreased with increase in filler concentration. Surface hardness was highest in the PMMA group with non-silanated nano particles as fillers at 5% concentration. In both groups the surface hardness improved with an increase in filler concentration. ANOVA and TUKEY’s HSD test were used. P<0.05 was considered statistically significant. Conclusion. Lower concentrations of surface-treated silica nanoparticles should be used as fillers to enhance the flexural strength of commercially available heat polymerized acrylic resin. Bangladesh Journal of Medical Science Vol.23 (Special Issue) 2024 p.S79-S86
Effects of Switching from Degludec to Glargine U300 in Patients with Insulin-Dependent Type 1 Diabetes: A Retrospective Study

Background and Objectives: Degludec (Deg) and glargine U300 (Gla-300) are insulin analogs with longer and smoother pharmacodynamic action than glargine U100 (Gla-100), a long-acting insulin that has been widely used for many years in type 1 and type 2 diabetes. Both improve glycemic variability (GV) and the frequency of hypoglycemia, unlike Gla-100. However, it is unclear which insulin analog affects GV and hypoglycemia better in patients with insulin-dependent type 1 diabetes. We evaluated the effects of switching from Deg to Gla-300 on the day-to-day GV and the frequency of hypoglycemia in patients with insulin-dependent type 1 diabetes treated with Deg-containing basal-bolus insulin therapy (BBT). Materials and Methods: We conducted a retrospective study on 24 patients with insulin-dependent type 1 diabetes whose treatment was switched from Deg-containing BBT to Gla-300-containing BBT. We evaluated the day-to-day GV measured as the standard deviation of fasting blood glucose levels (SD-FBG) calculated by the self-monitoring of blood glucose records, the frequency of hypoglycemia (total, severe, and nocturnal), and blood glucose levels measured as fasting plasma glucose (FPG) levels and hemoglobin A1c (HbA1c). Results: The characteristics of the patients included in the analysis with high SD-FBG had frequent hypoglycemic events, despite the use of Deg-containing BBT. For this population, SD-FBG and the frequency of nocturnal hypoglycemia decreased after the switch from Deg to Gla-300. Despite the decrease in the frequency of nocturnal hypoglycemia, the FPG and HbA1c did not worsen by the switch. The change in the SD-FBG had a negative correlation with the SD-FBG at baseline and a positive correlation with serum albumin levels. Conclusions: Switching from Deg to Gla-300 improved the SD-FBG and decreased the frequency of nocturnal hypoglycemia in insulin-dependent type 1 diabetes treated with Deg-containing BBT, especially in cases with low serum albumin levels and a high GV.
Developmental Changes of the Responses to Peer Assessment of Group Projects: a Case Study of Civil Engineering Undergraduates

The changes in the responding behaviour to peer assessments of group projects as students progress through their studies were explored to assist educators in designing peer assessment tools to suit students’ maturity levels and better understand the students’ responses to peer assessments. We collected and analysed the responses to a peer assessment tool after group project assignments of a group of civil engineering undergraduate students in their second and third years. The responses displayed a relatively higher satisfaction level by the students on their peers’ contribution to the group projects in both units, with a markedly higher satisfaction level in the third year of study than in the second year. The data also suggests that smaller groups tend to have higher peer satisfaction levels among group members than in bigger groups. Average peer rating versus group mark comparison was identified as a reliable indicator to identify groups that had internal issues while working on group projects but were not openly disclosed. Responses to individual criteria of the peer assessment tool confirmed that the group members are highly satisfied with each other’s attendance in group meetings and are increasingly satisfied with each other’s intellectual contribution towards the group project as the year level progresses. Given the participants in this study belong to one specific discipline, the results may not be generalisable to the entire student population, and we encourage more research in this area.
Global Impacts of Arctic Sea Ice Loss Mediated by the Atlantic Meridional Overturning Circulation

We explore the global impacts of Arctic sea ice decline in climate model perturbation experiments focusing on the temporal evolution of induced changes. We find that climate response to a realistic reduction in sea ice cover varies dramatically between shorter decadal and longer multidecadal to centennial timescales. During the first two decades, when atmospheric processes dominate, sea ice decline induces a “bipolar seesaw” pattern in surface temperature with warming in the Northern and cooling in the Southern Hemisphere, leading to a northward displacement of the Intertropical Convergence Zone and an expansion of Antarctic sea ice. In contrast, on multidecadal and longer timescales, the weakening of the Atlantic meridional overturning circulation, caused by upper‐ocean buoyancy anomalies spreading from the Arctic, mediates direct sea ice impacts and nearly reverses the original response pattern outside the Arctic. The Southern Hemisphere warms, a Warming Hole emerges in the North Atlantic, the Intertropical Convergence Zone shifts southward, and Antarctic sea ice contracts.
Drivers of Rural Housing Development in Edo State, Nigeria

Rural housing development is pivotal to tackling housing deficit in Nigeria. This study examines the challenges on existing housing structure in Ebele community, Benin City, Nigeria. It inquires into the housing finance structure, factors influencing its housing development and the infrastructural needs in the housing sector. It samples 30 residents from each of the five villages in Ebele community of Edo State. Using frequency counts and mean values, the result revealed that a considerable gap exists on the housing performance. The challenges being faced were majorly infrastructural deficits and shortage of capital. Innovative housing finance strategies were essentially lacking. Cultural and ethnic factors, neighbourhood factors, and infrastructural factors were rated the top drivers of housing development in the area. The study concluded that while addressing the drivers of rural housing development and tackling the challenges thereof, it is important to take into consideration the cultural values of the people. An integrated approach to rural housing development could bring about the required balance in housing development in rural and urban areas.
Defining “water resilience”: Debates, concepts, approaches, and gaps

Resilience is increasingly applied the context of water systems, and water governance more broadly, in response to climate change impacts, hydrologic variability and uncertainty associated with various dimensions of global environmental change. However, the meanings, applications and implications of resilience as it relates to water governance are still poorly understood. Drawing on a systematic scoping review of the peer‐reviewed academic literature, this paper addresses the questions: how is resilience framed in relation to water systems and water governance, how are diverse resilience framings (re)shaping ideas and trends in water management, and what are the associated implications? The analysis found that the resilience‐informed water governance literature remains fragmented and predominantly centered on conventional approaches and framings of water planning, with a predominant focus on engineering resilience in water supply infrastructure. A recently emerging engagement with resilience in the water governance literature, however, draws on more diverse framings and theories and calls for a shift towards more integrative and ecologically‐centered thinking in water governance. Despite this, significant empirical and conceptual gaps remain, particularly around the integration of the various subsectors of water governance and, more importantly, around the institutional and governance dimensions of building water resilience.
Canopy Cover Estimation from Landsat Images: Understory Impact onTop-of-canopy Reflectance in a Northern Hardwood Forest

Abstract In northern hardwood forests, light availability is considered to be the main factor limiting seedling and sapling growth. However, field measurement of this variable is time-consuming. To address this issue, we developed random forest regression models to estimate canopy cover from a Landsat 8 OLI image of a northern hardwood forest in northwestern New Brunswick, Canada. We then assessed the accuracy of model predictions with a canopy height model (CHM) derived from LiDAR data. We selected 2 threshold heights (1.3 and 5 m) to distinguish the understory from the overstory and to determine the impact of the understory on top-of-canopy reflectance. Our results show that the understory influenced top-of-canopy reflectance and that a 1.3 m height threshold provided the most accurate estimation of canopy cover. In contrast with studies conducted in softwood stands, we found no evidence that the shortwave infrared (SWIR1) band decreased the influence of the understory on top-of-canopy reflectance. In northern hardwood forests, the estimation of canopy characteristics, such as canopy cover and leaf area index, should be focused on the green band, as it was least influenced by understory vegetation.
Analyzing changes in parkinsonian speech over time: a diachronic experimental phonetics study

In this contribution the use of web resources for the longitudinal study of speech rhythm of a ‘well-known’ person diagnosed with Parkinson’s disease, the American actor Alan Alda, is proposed. A corpus of 20 speech samples produced in the period between 1979 and 2021 was collected from the web. A rhythmical analysis was conducted, based on two parameters: the percentage of vocalic portion on the total duration of the utterance (%V) and the VtoV, the mean duration of the interval between two consecutive vowel onset points. The results of this study confirm an early alteration of rhythm in parkinsonian speech, with an abnormal increase of %V, already occurring some years before the clinical diagnosis. The observation of speech rhythm variation can therefore be considered as the basis for the realization of a sustainable and non-invasive procedure in support to early diagnosis of Parkinson’s disease.
Mental workload assessment by monitoring brain, heart, and eye with six biomedical modalities during six cognitive tasks

Introduction The efficiency and safety of complex high precision human-machine systems such as in aerospace and robotic surgery are closely related to the cognitive readiness, ability to manage workload, and situational awareness of their operators. Accurate assessment of mental workload could help in preventing operator error and allow for pertinent intervention by predicting performance declines that can arise from either work overload or under stimulation. Neuroergonomic approaches based on measures of human body and brain activity collectively can provide sensitive and reliable assessment of human mental workload in complex training and work environments. Methods In this study, we developed a new six-cognitive-domain task protocol, coupling it with six biomedical monitoring modalities to concurrently capture performance and cognitive workload correlates across a longitudinal multi-day investigation. Utilizing two distinct modalities for each aspect of cardiac activity (ECG and PPG), ocular activity (EOG and eye-tracking), and brain activity (EEG and fNIRS), 23 participants engaged in four sessions over 4 weeks, performing tasks associated with working memory, vigilance, risk assessment, shifting attention, situation awareness, and inhibitory control. Results The results revealed varying levels of sensitivity to workload within each modality. While certain measures exhibited consistency across tasks, neuroimaging modalities, in particular, unveiled meaningful differences between task conditions and cognitive domains. Discussion This is the first comprehensive comparison of these six brain-body measures across multiple days and cognitive domains. The findings underscore the potential of wearable brain and body sensing methods for evaluating mental workload. Such comprehensive neuroergonomic assessment can inform development of next generation neuroadaptive interfaces and training approaches for more efficient human-machine interaction and operator skill acquisition.
Humoral complementomics – exploration of noninvasive complement biomarkers as predictors of renal cancer progression

ABSTRACT Despite the progress of anti-cancer treatment, the prognosis of many patients with solid tumors is still dismal. Reliable noninvasive biomarkers are needed to predict patient survival and therapy response. Here, we propose a Humoral Complementomics approach: a work-up of assays to comprehensively evaluate complement proteins, activation fragments, and autoantibodies targeting complement proteins in plasma, which we correlated with the intratumoral complement activation, and/or local production, focusing on localized and metastatic clear cell renal cell carcinoma (ccRCC). In two prospective ccRCC cohorts, plasma C2, C5, Factor D and properdin were elevated compared to healthy controls, reflecting an inflammatory phenotype that correlated with plasma calprotectin levels but did not associate with CRP or with patient prognosis. Conversely, autoantibodies against the complement C3 and the reduced form of FH (a tumor neo-epitope reported in lung cancer) correlated with a favorable outcome. Our findings pointed to a specific group of patients with elevated plasma C4d and C1s-C1INH complexes, indicating the initiation of the classical pathway, along with elevated Ba and Bb, indicating alternative pathway activation. Boostrapped Lasso regularized Cox regression revealed that the most predictive complement biomarkers were elevated plasma C4d and Bb levels at the time of surgery, which correlated with poor prognosis. In conclusion, we propose Humoral Complementomics as an unbiased approach to study the global state of the complement system in any pathological plasma sample and disease context. Its implementation for ccRCC revealed that elevated C4d and Bb in plasma are promising prognostic biomarkers, correlating with shorter progression-free survival.
Effect of Gold Nanorods on the Performance of Polymer:Fullerene Organic Solar Cells

This research is an experimental investigation on the effect of inserting gold nanorods in various locations of conjugated polymer solar cells that comprise poly(3-hexylthiophene-2,5-diyl) as the electron donor, and [6,6]-phenyl-C61-butyric-acid-methyl-ester as the electron acceptor, on the cells performance. Since gold nanorods support at least two major plasmonic modes associated with metallic nanoparticles, incorporating such nanoparticles into thin films of polymer solar cells is supposed to trap light inside the cells in a broad wavelength range, leading to increasing absorptivity as well as power conversion efficiency. First, several experiments were performed to manufacture devices with a good and reproducible efficiency by optimizing the fabrication conditions, particularly the lithium fluoride thickness as well as the annealing process. This optimization succeeded in producing reproducible devices with an enhanced power conversion efficiency from 0.36% to 1.67%. Secondly, various approaches were used to introduce gold nanorods in our devices. Rods were deposited in contact with either the cells’ front electrode, or the rear one. They were also blended with the solution of the anodic buffer layer, or the one of the photoactive layer. We compared the photovoltaic parameters extracted from completed devices made with/without gold nanorods, as well as their spectroscopic and structure properties. We found that for each location of rods in our devices there was an optimal concentration of the rods to produce enhancement in the devices’ performance. Based on theoretical considerations, devices enhancement was related to either the far field or near field effect induced by the presence of rods. It was found that increasing or decreasing the rods density from the optimal one reduced the overall efficiency of resulting devices. We experimentally verified that there was a relationship between the enhancement in the devices efficiency and the multi-mode excitations associated with gold nanorods. We also found that the influence of plasmonics on absorption of the devices depended on the thickness of the devices’ photoactive layers. Using the rod shape of gold nanoparticles to increase the device performance is indeed a promising approach since a fairly low density of the rods in the layer succeeded in increasing remarkably the devices efficiency by up to 21.3 %.
Presence of Alphacoronavirus in Tree- and Crevice-Dwelling Bats from Portugal

Coronaviruses (CoVs) are RNA viruses capable of infecting a wide range of hosts, including mammals and birds, and have caused significant epidemics such as the ongoing COVID-19 pandemic. Bats, the second most diverse mammalian order, are hosts for various CoVs due to their unique immune responses and ecological traits. This study investigates CoV prevalence in crevice- and tree-dwelling bats in Portugal, a country with limited prior research on bat CoVs. Using nested RT-PCR and sequencing, we screened 87 stool samples from bats, identifying one sample (1.15%) that was positive for Alphacoronavirus, belonging to Pipistrellus pipistrellus. Phylogenetic analysis revealed close genetic relationships with Alphacoronavirus strains from the same bat species in Europe. The low prevalence suggests habitat-specific differences in viral transmission, with cave-dwelling bats exhibiting higher CoV prevalence due to population density and behaviour. These findings underscore the necessity for sustained surveillance efforts aimed at comprehending CoV dynamics within bat populations, especially concerning the risk of spillover events and viral evolution. Vital to this understanding is the monitoring of bat migration patterns, which serves as a crucial tool for elucidating CoV ecology and epidemiology. Such efforts are essential for ongoing research endeavours aimed at mitigating the potential for future zoonotic disease outbreaks.
Mid- to late Holocene cooling events in the Korean Peninsula and their possible impact on ancient societies

Abstract We present a multiproxy record using pollen, magnetic susceptibility, carbon isotopic composition, carbon/nitrogen ratio, and particle size of mid- to late Holocene environmental changes based on a sediment core from the Pomaeho lagoon on the east coast of Korea. The records indicate that climate deteriorations around 6400 cal yr BP and 4000 cal yr BP caused rapid vegetation changes in the study area, which were presumably attributable to low sunspot activity and strong El Niño–like conditions, respectively. These two cooling events were likely modulated by different climate mechanisms, as El Niño–Southern Oscillation activity began to strengthen around 5000 cal yr BP. These events may have had a substantial impact on ancient societies in the study area. Combining our results with archaeological findings indicated that climate deterioration led to drastic declines in local populations around 6400 cal yr BP, 4400 cal yr BP, and 4000 cal yr BP. Because of its high population, coastal East Asia (e.g., eastern China, Japan, and Korea) is particularly vulnerable to potential cooling events in the future. Therefore, there is a strong need for detailed paleoclimate information in this region.
Enhancing Consumer Visual Experience through Visual Identity of Dynamic Design: An Integrative Literature Review

Issues: With the advent of the digital era, more than static visual identity design is needed to meet the aesthetic demands of contemporary consumers. This research explores enhancing consumer visual experiences through dynamic visual identity design. Methodology: By focusing on the elements and evaluation criteria of visual identity, along with relevant theories, this study establishes a conceptual framework emphasizing the significance of dynamic visual elements, visual experiences
Reproducibility of San Andreas Fault Slip Rate Measurements at Wallace Creek in the Carrizo Plain, CA

Reproducibility of results from scientific studies is rarely demonstrated outside the laboratory. Measurements of fault slip rate underpin scientific models of active faulting and seismic hazard assessments widely used for policymaking and risk mitigation. We replicated a highly referenced study that measured the slip rate as 33.9 ± 2.9 mm/year along the San Andreas fault over the past ~3,700 years at Wallace Creek in the Carrizo Plain National Monument, USA. Our results provide a slip rate of slip 36 ± 1 mm/year since ~3,500 CalBP. We find that the late Holocene slip rate of the San Andreas fault, a key indicator of seismic hazard, is reproducible within measurement uncertainty. Geologic slip rate determinations are relatively insensitive to short‐term fluctuations and thus should be reproducible if the time interval of measurement is much greater than the average rupture interval.