Miracle-dz/UniFAR-FTUs huggingface dataset:
KNOWLEDGE OF OVULATORY CYCLE AND ASSOCIATED FACTORS AMONG REPRODUCTIVE AGE WOMEN IN NIGERIA

Relevance. The break-up and exit of the dominant follicle into the fallopian tube from the ovary is a physiological event known as ovulation. To determine fertility chances, it is essential to understand the physiology of the ovulatory cycle. Objective. This study assesses the knowledge of the ovulatory cycle (KOC) and associated factors among reproductive-age women in Nigeria. Materials and methods. The research was based on 2018 NDHS data (which was the most current at the time of this study). 90,290 women of reproductive age were taken into account for this investigation. The methods of analysis used are percentage, frequency, chi-square test and Binary Logistic Regression Analysis. p<0.05 was considered to be statistically significant. Results. Only 25% of the 90,290 reproductive women included in the investigation were found to be knowledgeable of the ovulatory cycle. The study revealed that age, region, place of residence (urban), religion, marital status (living with a partner), maternal education (primary and higher education), husband's educational level and women's media exposure had a significant effect on knowledge of the ovulatory cycle. Conclusion. KOC, however, was low (25%), necessitating the development and implementation of reproductive health services through community media campaigns and health promotion. The authors of this study urge the Nigerian Ministry of Health to prioritize improving the reproductive health of women by prioritizing adolescents and those with less education. Additionally, media initiatives might be strengthened to improve women's KOC, which is essential for preventing unwanted pregnancy.
Does corporate governance moderate the effect of corporate social responsibility on a firm’s financial performance?

Drawing on the agency and resource dependence theories, the paper assumes that the impact of corporate social responsibility on companies’ financial performance should be investigated not in a binary manner but against the backdrop of corporate governance. The analysis is based on testing the dataset retrieved from the Chinese Stock Market and Accounting Research database containing 28,200 company-year observations of 3,576 Chinese listed companies covering 2008–2019. The findings accentuate that corporate social responsibility, interacting with board size, equity concentration, and CEO duality, positively impacts a firm’s financial performance. In contrast, the study fails to substantiate the claim that board gender diversity and board independence moderate the bond between corporate social responsibility and financial performance. Thus, by exploring five elements of corporate governance, this study takes a step forward in understanding exactly which elements of corporate governance best suit corporate social responsibility to enhance financial performance in China’s institutional settings. This study assists in filling the gap in corporate social responsibility research by displaying and corroborating the moderating effects of corporate governance attributes on the nexus between corporate social responsibility and financial performance in China. Therefore, this paper presents valuable information and details for companies and regulators alike to improve the impact of corporate social responsibility on financial performance by focusing on corporate governance quality. AcknowledgmentThis paper is co-funded by European Union through the European Education and Culture Executive Agency (EACEA) within the project “EU Best Practice Of Life Cycle Assessment, Social, Environmental Accounting And Sustainability Reporting 101047667 – EULASTING – ERASMUS-JMO-2021-HEI-TCH-RSCH” (https://bit.ly/3Bbvquw).
Dendritic Cell-Triggered Immune Activation Goes along with Provision of (Leukemia-Specific) Integrin Beta 7-Expressing Immune Cells and Improved Antileukemic Processes

Integrin beta 7 (β7), a subunit of the integrin receptor, is expressed on the surface of immune cells and mediates cell–cell adhesions and interactions, e.g., antitumor or autoimmune reactions. Here, we analyzed, whether the stimulation of immune cells by dendritic cells (of leukemic derivation in AML patients or of monocyte derivation in healthy donors) leads to increased/leukemia-specific β7 expression in immune cells after T-cell-enriched mixed lymphocyte culture—finally leading to improved antileukemic cytotoxicity. Healthy, as well as AML and MDS patients’ whole blood (WB) was treated with Kit-M (granulocyte–macrophage colony-stimulating factor (GM-CSF) + prostaglandin E1 (PGE1)) or Kit-I (GM-CSF + Picibanil) in order to generate DCs (DCleu or monocyte-derived DC), which were then used as stimulator cells in MLC. To quantify antigen/leukemia-specific/antileukemic functionality, a degranulation assay (DEG), an intracellular cytokine assay (INTCYT) and a cytotoxicity fluorolysis assay (CTX) were used. (Leukemia-specific) cell subtypes were quantified via flow cytometry. The Kit treatment of WB (compared to the control) resulted in the generation of DC/DCleu, which induced increased activation of innate and adaptive cells after MLC. Kit-pretreated WB (vs. the control) led to significantly increased frequencies of β7-expressing T-cells, degranulating and intracellular cytokine-producing β7-expressing immune cells and, in patients’ samples, increased blast lysis. Positive correlations were found between the Kit-M-mediated improvement of blast lysis (vs. the control) and frequencies of β7-expressing T-cells. Our findings indicate that DC-based immune therapies might be able to specifically activate the immune system against blasts going along with increased frequencies of (leukemia-specific) β7-expressing immune cells. Furthermore, β7 might qualify as a predictor for the efficiency and the success of AML and/or MDS therapies.
Effect of antisite defects on band structure and thermoelectric performance of ZrNiSn half-Heusler alloys

Band structures for ZrNiSn with Zr/Sn antisite defects are calculated with ab initio methods. Antisite defects shrink the band gap and enhance the density of states slope near the Fermi level, which are favorable to electrical transport properties for intrinsic semiconductors. The degree of Zr/Sn antisite defects are controlled by annealing time experimentally, and measurements show low electrical resistivity and high Seebeck coefficient for unannealed ZrNiSn, which benefits from the modified electronic structure caused by antisite defects. The maximum ZT is 0.64 at 800 K for unannealed ZrNiSn, which is the highest value for ZrNiSn systems without exterior doping.
Cumulative lifetime stressor exposure and health in elite athletes: the moderating role of perfectionism

Although greater lifetime stressor exposure has been associated with physical and mental health issues in the general population, relatively little is known about how lifetime stressors impact the physical and mental health of elite athletes or the factors moderating this association. Given that many elite athletes show signs of perfectionism, and that this trait has been linked with illhealth, it is possible that perfectionism may moderate the lifetime stressor-health relationship. To test this possibility, we examined how cumulative lifetime stressor exposure was associated with general mental and physical health complaints in elite athletes, and the extent to which these associations were moderated by perfectionism. Participants were 110 elite athletes (64 female; Mage = 29.98 years, SD= 10.54) who completed assessments of lifetime stressor exposure, physical health, psychological distress, and perfectionism. As hypothesised, hierarchical regression analyses revealed that experiencing more severe lifetime stressors was related to poorer physical and mental health. Furthermore, selforiented perfectionism moderated the association between lifetime stressor count and severity and physical health, but not mental health. Overall, these data demonstrate stressor-specific effects among elite athletes and highlight the potential importance of assessing lifetime stressor exposure and perfectionistic tendencies in order to improve athlete health and well-being. ARTICLE HISTORY Received 30 August 2022 Accepted 31 October 2022
Therapeutic delivery of microRNA-125a-5p oligonucleotides improves recovery from myocardial ischemia/reperfusion injury in mice and swine

Rationale: Clinical application of mesenchymal stem cells (MSCs) and MSC-derived exosomes (MSC-Exos) to alleviate myocardial ischemia/reperfusion (I/R) injury is compromised by the low cell engraftment rate and uncontrolled exosomal content. As one of their active ingredients, single-component microRNA therapy may have more inherent advantages. We sought to find an ideal microRNA candidate and determine whether it could reproduce the cardioprotective effects of MSCs and MSC-Exos. Methods: Cardiac function and myocardial remodeling in MSC, MSC-Exo, or microRNA oligonucleotide-treated mouse hearts were investigated after I/R injury. The effects of microRNA oligonucleotides on cardiac cells (macrophages, cardiomyocytes, fibroblasts, and endothelial cells) and their downstream mechanisms were confirmed. Large animals were also employed to investigate the safety of microRNA therapy. Results: The results showed that microRNA-125a-5p (miR-125a-5p) is enriched in MSC-Exos, and intramyocardial delivery of their modified oligonucleotides (agomir) in mouse I/R myocardium, as well as MSCs or MSC-Exos, exerted obvious cardioprotection by increasing cardiac function and limiting adverse remodeling. In addition, miR-125a-5p agomir treatment increased M2 macrophage polarization, promoted angiogenesis, and attenuated fibroblast proliferation and activation, which subsequently contributed to the improvements in cardiomyocyte apoptosis and inflammation. Mechanistically, Klf13, Tgfbr1, and Daam1 are considered the targets of miR-125a-5p for regulating the function of macrophages, fibroblasts, and endothelial cells, respectively. Similar results were observed following miR-125a-5p agomir treatment in a porcine model, with no increase in the risk of arrhythmia or hepatic, renal, or cardiac toxicity. Conclusions: This targeted microRNA delivery presents an effective and safe strategy as a stem cell and exosomal therapy in I/R cardiac repair.
Detection of hepatitis E virus RNA from pig bile collected at a slaughterhouse in Japan

Hepatitis E virus (HEV) is a zoonotic pathogen that circulates mainly between pigs and humans. In Japan, the number of confirmed HEV cases has increased over the past decade, with the majority reported as domestic HEV infections. HEV-infected pork products may be associated with this increase, but there is limited information on HEV in pork in Japanese markets. From February to March 2020, gallbladders were collected from 200 slaughtered pigs shipped from 14 farms and were surveyed to detect HEV RNA in bile using reverse transcription quantitative polymerase chain reaction. The samples were then sequenced and genotyped. Twenty pigs were positive for HEV ribonucleic acid, and seven samples had Ct values of less than 30. Among these 20 pigs, virus strains from 14 pigs were determined as genotype 3. This report indicated that HEV-contaminated pork liver was shipped to consumer markets and demonstrated the importance of detection of HEV in meat ready for shipment.
Local Sensitivity of Inferences to Prior Marginals

Abstract The sensitivity of posterior expectations to perturbations of prior marginals is investigated, using a local method. This approach is particularly well suited to high-dimensional parameter spaces. Qualitative and quantitative results are obtained regarding the propagation of sensitivity in multiparameter settings. More specifically, a posterior expectation is treated as a functional of the prior marginal. The derivative of this functional is evaluated at the nominal prior marginal, yielding a measure of sensitivity. This is computationally more feasible than evaluating the range of a posterior quantity over a class of priors; hence sensitivity can be assessed in high-dimensional problems. The local technique is used to assess the influence of distributional assumptions at the various stages of a hierarchical model.
Modeling the impact of green energy consumption and natural resources rents on economic growth in Africa: An analysis of dynamic panel ARDL and the feasible generalized least squares estimators

Abstract The United Nations Sustainable Development Goals (SDGs) 7, 11, and 12 are all aimed at advancing green energy consumption in the fight against the three planetary crises facing the world today: climate change, biodiversity loss, and pollution. Besides, Africa has an abundance of natural resources, yet, the continent continues to witness slow growth and development compared to its counterparts. Therefore, this study, the first of its kind, simultaneously assesses the impact of green energy consumption and natural resources rents on economic growth by applying the dynamic panel ARDL and the Feasible Generalized Least Square (FGLS) estimators on data from 1990 to 2020 for 24 selected African countries. The results show that green energy consumption has a short-run growth-limiting and a long-run growth-enhancing effect in Africa. Also, CO2 emissions have both short- and long-run significant positive impacts on economic growth, while fossil fuel combustion negatively impacts growth both in the short and long run, albeit the effect is not significant in the long run. Similarly, regarding Africa’s natural resource rents’ impact on growth, the results show that total natural resource rents are growth-enhancing in the short run and growth-limiting in the long run. Additionally, both forest and mineral rents have a significant short-run negative impact on growth in Africa. However, in the long run, only the effect of mineral rent is growth-enhancing although generally not statistically significant. These findings provide relevant implications for policy shifts to enhance environmental sustainability, achieve sustainable economic growth, and ensure proper natural resources management in Africa.
Implications of rapid planetary rotation for the Dungey magnetotail of Saturn

[1] Employing our current understanding of the structure and dynamics of Saturn's magnetosphere, we present a time-dependent model of the kronian Dungey cycle magnetotail, which is based upon a modification of a similar model developed for Earth's magnetotail (Milan, 2004a). The major difference arises due to the rapid rotation of Saturn and the partial corotation that this imposes on the open field lines threading the polar cap. This results in twisted tail lobes, with the form of concentric cylinders of oldest to newest open flux from the inside out. The oldest, and hence longest, open field lines form the backbone of a highly extended magnetotail. Surrounding this are bundles of field lines disconnected by tail reconnection, propagating down-tail at the solar wind speed. Owing to the twisted nature of the tail, these bundles remain entangled with the lobe cores to form “exterior flux ropes. ” In the limit that the addition and removal of open flux from the magnetosphere by magnetic reconnection can be treated as a last-in-first-out system, we formulate a description of the flux transport within the tail and drive this with estimated dayside reconnection voltages deduced from Cassini observations of the IMF made upstream of Saturn (Jackman et al., 2004).
Assessment of Toxicity of Parthenium hysterophorus L. Extract against Larvae of Trogoderma granarium

The leaves of parthenium (Parthenium hysterophorus L.) were extracted in ethanol and toxicity of the extract was examined on khapra beetle (Trogoderma granarium Everts) larvae. Four concentrations (2, 4, 6 and 8 µL mL-1 acetone) were applied directly on the larvae in Petri dishes. Toxicity was recorded after 12, 24 and 36 h. All the concentrations had considerable effect on the mortality of larvae. At the highest concentration (8 µL mL-1), the mortality observed was 57%, 72% and 78% after 12, 24 and 36 h, respectively. The minimum mortality was observed to be 43% at the concentration of 2 µL mL-1 acetone after 12 h. GC-MS analysis of the parthenium leaves showed 7 compounds in the extract including phytol (38.68%), β-cubebene (11.98%), hexadecanoic acid, methyl ester (11.22%), caryophyllene (10.37%), 9,12,15-octadecatrienoic acid, ethyl ester, (Z,Z,Z)- (9.98%), methyl stearate (9.01%), and hexadecanoic acid, ethyl ester (8.74%). The study concluded that an extract of 8 µL mL-1 acetone concentration is highly effective against larvae of khapra beetles that can cause 78% mortality after 36 h of direct exposure to the larvae.
Photovoltaic and Ferroelectric Properties of Pb0.95La0.05Zr0.54Ti0.46O3 Thin Films under Dark and Illuminated Conditions

Thin films of Pb0.95La0. 05Zr0.54Ti0. 46O3 were prepared using chemical solution method. The photovoltaic response of the films under dark and illuminated conditions was investigated using capacitor type devices with Pt as top and bottom electrodes. The results show that the open circuit voltage and the short circuit current of a capacitor type cell can be manipulated by controlling the post deposition annealing temperature of the films. Films annealed at 750°C were seen to exhibit the highest short circuit current of 15.83 nA. The influence of illumination on properties such as capacitance, ferroelectric polarization and leakage current was studied. The capacitance of the film was seen to decrease when illuminated with light (60mW/cm2), suggesting that illumination leads to generation of charge carriers. The films became leaky under illumination, resulting in an increase in leakage current by an order of magnitude compared to the dark conditions. The saturation polarization (Ps) was suppressed, whereas the remnant polarization (Pr) was not affected under illumination. Further, a shift in the hysteresis loop, along the voltage axis, was observed under illuminated conditions. This shift is attributed to the change of a space-charge field with illumination.
Improvement in quality of frozen Jersey bull semen following fortification with chloroquine diphosphate and ascorbic acid

The present study was conducted with an objective of studying the role of certain additives e.g. chloroquine diphosphate and ascorbic acid in maintaining the membrane integrity, viability and motility of spermatozoa at various pre- and post-freezing stages of semen of Jersey bulls maintained under sub-temperate climate. Work was conducted at Sperm Station Palampur, Himachal Pradesh, India, on six apparently healthy pure bred Jersey breeding bulls. A total of 36 ejaculates (6 from each bull), were analysed at six different stages of processing namely neat semen evaluation, post-dilution, post-equilibration, post-thaw and after 1 and 2 h incubation post-thaw at 37Â°C for progressive motility, live dead count, reaction to hypo-osmotic solution and acrosomal integrity, respectively. Evaluation of the semen was done for three groups, i.e. control group (G1), semen fortified with chloroquine diphosphate (G2) and ascorbic acid (G3). The results of the study revealed a significant improvement in progressive motility, live sperm percentage, reaction to hypo-osmotic solution and acrosomal integrity of semen having chloroquine diphosphate (G2) and ascorbic acid (G3) as additives when compared to control group. So, fortification of semen should be done with chloroquine diphosphate and ascorbic acid to improve the quality of semen in future.
Amelioration of Autoimmunity in a Lupus Mouse Model by Modulation of T‐Bet–Promoted Energy Metabolism in Pathogenic Age/Autoimmune‐Associated B Cells

Emerging evidence indicates that a distinct CD11c+T‐bet+ B cell subset, termed age/autoimmune‐associated B cells (ABCs), is the major pathogenic autoantibody producer in lupus. Human lupus is associated with significant metabolic alterations, but how ABCs orchestrate their typical transcription factors and metabolic programs to meet specific functional requirements is unclear. We undertook this study to characterize the metabolism of ABCs and to identify the regulators of their metabolic pathways in an effort to develop new therapies for ABC‐mediated autoimmunity.
Multilinear algebra for independent component analysis

It is shown how some simple multilinear transformations may be used to generate an alternative, and potentially faster, version of the BLISS algorithm for blind signal separation. The BLISS algorithm performs an independent component analysis of the type proposed by Comon but uses a different method for estimating the pairwise rotation angles. It has been applied to a wide range of communication signals and proved extremely successful in practice. The reformulated version of BLISS requires less arithmetic operations provided the number of signals to be separated is fairly small (approximately 3 to 5) as found in a range of important communication scenarios.
Factors influencing calf mortality in zebu and crossbred cattle reared under subtropical agroclimatic conditions

Data on birth weight and mortality pattern of Zebu (Sahiwal and Tharparkar) and Crossbred (Holstein Friesian Ã— Tharparkar) cattle spread over 16 years were utilized to analyze the causes of calf mortality and to study the effect of non-genetic factors on calf mortality. Calf mortality was higher in crossbred (27.7%) compared to either Sahiwal (20.7%) or Tharparkar cattle (11.9%). Age group wise analysis revealed maximum mortality within one month age in Zebu cattle, and during 1â€“3 months age in crossbred cattle. Mortality was higher in calves born during winter, summer and rainy seasons in Sahiwal, crossbred and Tharparkar, respectively. Mortality was higher among male calves compared to female calves. Significantly higher proportion of Sahiwal calves died due to respiratory problems, while general debility was the major reason for calf mortality in crossbred and Tharparkar cattle. Season of birth had highly significant influence within one month age in Sahiwal and crossbred cattle. Influence of all the non genetic factors on calf mortality at various age groups was found to be non significant in Tharparkar cattle. It is inferred that calf mortality was higher in crossbred compared to Zebu cattle and the effect of season of birth and birth weight had a significant effect on calf mortality during first three months age. Among the several causes, respiratory problem was a significant reason for the calf mortality.
Examination of Coupled Continuum Fluid Dynamics and Radiation in Hypersonic Simulations

Two nonequilibrium hypersonic CFD tools are compared to one another, including tightly-coupled radiation. DPLR and LAURA have di erent models for the separation of nonequilibrium energy. As a result, results from both codes show significant di erences in flowfield temperatures. The flows considered in the present paper are from FIRE II, and from Stardust reentry. Both codes predict convective heat fluxes on the vehicle surfaces within 5% of one another. However, there are significant di erences in predicted radiative transport, as well as in the e ects of flowfield coupling. The present comparison demonstrates that, for future calculations, free electron temperature needs to be coupled to the vibrational temperature. in DPLR