Miracle-dz/UniFAR-FTUs huggingface dataset:
Ultrafast Nuclear Dynamics Induced by Light from the XUV to the THz Range

With recent advances in the generation of ultrashort laser pulses, electron and nuclear dynamics in molecules can be investigated on their natural, attoto femtosecond timescale. This opens up the investigation of many interesting phenomena, including primary events in chemistry and biology. The new experimental capabilities are complemented by theoretical investigation to develop a better insight in the nature of ultrafast processes. In this thesis, I will theoretically explore ultrafast nuclear dynamics that are triggered by light over a wide range of the electromagnetic spectrum — from extreme ultraviolet (XUV) to terahertz (THz) radiation. The results are obtained by ab initio methods for both electrons and nuclei. Photoionization using attosecond, coherent, XUV pulses can create coherent superpositions of electronic states of the cation. This initiates coherent electron dynamics, but also nuclear motion, that is often neglected in the interpretation of ultrafast experiments. I use a quantum-dynamical treatment of nuclear motion to show that electronic coherences are affected by the nuclei. Within an adiabatic model, they are destroyed within few femtoseconds. When non-adiabatic couplings are included, electronic coherences may be preserved to some extent. This highlights the importance of considering nuclear motion and nuclear quantum effects even when simulating electron dynamics on the few-femtosecond timescale. The non-adiabatic coupling of electron and nuclear motion allows to control nuclear dynamics through manipulating electronic degrees of freedom. Within a model system of a conical intersection, I explore the possibility of steering nuclei through imprinting a phase difference between electronic states with ultrashort, shaped pulses. Valence ionization triggers electron-hole dynamics that can be observed by timeresolved, transient x-ray absorption spectroscopy. To describe the hole dynamics, I present an expansion to our in-house software XMOLECULE for a mixed quantum-classical treatment of molecular dynamics in electronically excited states. First results on hole dynamics and corresponding x-ray absorption spectra are shown. Ultrafast nuclear motion can also be initiated through strong and short THz pulses, that couple to the intermolecular degrees of freedom of liquids like water. With current THz sources, water can be heated by more than 1000 Kelvin within 100 femtoseconds. I explore the signature of these ultrafast nuclear dynamics in the XUV photoelectron spectrum of liquid water. It is found that the spectral changes are close to the current experimental resolution.
Minimal Universal Two-qubit Quantum Circuits

We give quantum circuits that simulate an arbitrary two-qubit unitary operator up to global phase. For several quantum gate libraries we prove that gate counts are optimal in worst and average cases. Our lower and upper bounds compare favorably to previously published results. Temporary storage is not used because it tends to be expensive in physical implementations. For each gate library, best gate counts can be achieved by a single universal circuit. To compute gate parameters in universal circuits, we only use closed-form algebraic expressions, and in particular do not rely on matrix exponentials. Our algorithm has been coded in C++.
NUMERICAL INERTIA AND DAMPING COEFFICIENTS DETERMINATION OF A TUBE-BUNDLE IN INCOMPRESSIBLE VISCOUS LAMINAR FLUID

IN THIS PAPER, WE COMPARE THE PERFORMANCES OF TRANSPIRATION AND ALE METHODS. THE APPROACH ALE (ARBITRARY LAGRANGIAN EULERIAN) IS A POWERFUL TOOL TO TREAT COUPLED PROBLEMS, MORE PRECISELY, THE APPROACH ALE IN FINITE ELEMENTS OF DONEA AND HUGHES. HOWEVER, ALE PERFORMANCE FOR DETERMINING FLUID-ELASTIC FORCES AT SMALL VIBRATIONS AMPLITUDES IS STILL IGNORED. TRANSPIRATION METHOD IS A SIMPLIFIED APPROACH FOR CALCULATION OF FLUID-ELASTIC FORCES AT RELATIVELY SMALL VIBRATIONS AMPLITUDES. BASED ON A FIRST ORDER DEVELOPMENT OF VELOCITY BOUNDARY CONDITIONS, THIS METHOD ALLOWS THE USE OF A FLUID DOMAIN FIXED IN TIME DURING A DYNAMIC COMPUTATION, BY AVOIDING HENCE THE PROBLEMS DUE TO THE MESH DISTORTIONS. THE METHODS HAVE BEEN VALIDATED WITH HELP OF ANALYTICAL SOLUTION OF A VIBRATING CYLINDER IMMERSED IN STOKES CONFINED FLUID MEDIUM. WE MADE OTHERS ANALYSIS OF DYNAMICS CHARACTERISTICS IN TUBE-BUNDLE COMPARING WITH LITERATURE. THIS METHODS ARE IMPLEMENTED IN CAST3M A NUMERICAL PLATFORM OF FRENCH NUCLEAR AGENCY - CEA-SACLAY -.
Structural parameter study on polymer-based ultrasonic motor

Our previous study has shown that traveling-wave rotary ultrasonic motors using polymer-based vibrators can work in the same way as conventional motors with metal-based vibrators. It is feasible to enhance the performance, particularly output torques, of polymer-based motors by adjusting several key dimensions of their vibrators. In this study, poly phenylene sulfide, a functional polymer exhibiting low attenuation at ultrasonic frequency, is selected as the vibrating body, which is activated with a piezoelectric ceramic element bonded on its back surface. The optimal thicknesses of the polymer-based motors are higher than those of metal-based motors. When the same voltages were applied, the maximum torques and output powers available with the polymer-based motors were lower than the values of the metal-based motors with the same structures. The reasons for the lower torque were explained on the basis of vibration modes. First, the force factors of the polymer-based vibrators are lower than those of metal-based vibrators owing to the great difference in the mechanical constants between polymers and piezoelectric ceramics. Subsequently, though the force factors of polymer-based vibrators can be slightly enhanced by increasing their thicknesses, the unavoidable radial vibrations become higher and cause undesirable friction loss, which reduces the output torques. Though the polymer-based motors have rotation speeds comparable to those of metal-based motors, their output power are lower due to the low electromechanical coupling factors of the polymer-based vibrators.
Introduction: Artistic Work as a “Laboratory” of Labour Market Deregulation?

The arts can often command attention as a “laboratory” for the different forms of labour deregulation. It is not that artists have been ahead of the transformations of the labour market since the 1980s, but rather that they have, for the most part, escaped the standard of the modern wage system specific to industrial capitalism, now weakened by the hegemony of financial capitalism. The contributions to this volume, stemming from field inquiries in Switzerland, France and Germany, draw on various analytical tools in order to shed light on different artistic disciplines (theatre,music, dance, literature, visual arts), drawing parallels with other fields of employment and labour.
Pluripotent hematopoietic stem cells augment (cid:2) -adrenergic receptor-mediated contraction of pulmonary artery and contribute to the pathogenesis of pulmonary hypertension

Pluripotent hematopoietic stem cells augment (cid:2) -adrener-gic receptor-mediated contraction of pulmonary artery and contribute to the pathogenesis of pulmonary hypertension. Am J Physiol Lung Cell Mol Physiol 318: hypertension (PH) is a multicellular and progressive disease with a high mortality rate. Among many cell types, hematopoietic stem cells (HSCs) are incriminated in the pathogenesis of PH. However, our understanding of the mechanisms that increase HSCs in blood and lungs of hypertensive animals or patients and the role played by HSCs in the mice. Furthermore, knockdown of G6PD and inhibition of G6PD activity: 1 ) downregulated canonical and noncanonical Wnt and Fzd receptors genes; 2 ) upregulated Bmpr1a ; 3 ) decreased Cxcl12 , and 4 ) reduced HSC (CD117 (cid:3) and CD133 (cid:3) ) numbers. In all, our ﬁndings demonstrate unexpected function for bone marrow-derived HSCs in aug- menting (cid:2) -adrenergic receptor-mediated contraction of pulmonary arteries and remodeling of pulmonary arteries that contribute to increase pulmonary vascular resistance in PAH patients and hypoxic mice and suggest that G6PD, by regulating expression of genes in the WNT and BMPR signaling, contributed to increase and release of HSCs from the bone marrow in response to hypoxic stimuli.
CONHECIMENTO DO PROFISSIONAL ACERCA DO CUIDADO DE ENFERMAGEM À PESSOA COM ESTOMIA INTESTINAL E FAMÍLIA

Pesquisa convergente-assistencial que teve como objetivo conhecer o cuidado de enfermagem as pessoas submetidas a cirurgia de estomia intestinal, em um hospital universitario do Sul do pais. Foi realizada nas unidades de internacao cirurgicas, nos meses de abril a agosto de 2011, atraves de entrevista semiestruturada com os profissionais de enfermagem. Os dados foram analisados em quatro processos: apreensao, sintese, teorizacao e transferencia. Originaram as categorias: o conhecimento do profissional de enfermagem frente ao papel da pessoa com estomia intestinal para o autocuidado, o conhecimento do profissional de enfermagem com relacao ao papel da familia e formacao e atuacao profissional. Observou-se que a problematica da pessoa com estomia intestinal e complexa e determinante de condicoes especiais no atendimento a sua saude para a sua reabilitacao e autonomia.
COVID-19 Vaccine Booster Dose Willingness among Patients with Inflammatory Bowel Disease on Infliximab and Vedolizumab: A Cross-Sectional Study

Background: Vaccination has been effective in preventing COVID-19 infections and related mortality. However, waning immunity after the two-dose vaccination prompted health authorities to recommend a third dose of COVID-19 vaccine to boost immunity. The aim of our study was to assess willingness to receive a third (booster) dose among patients with IBD. Methods: A cross-sectional study was performed at a tertiary care inflammatory bowel disease center. Patients were recruited at the infusion room from January 1st, 2022, until March 31st, 2022. The primary outcome was the prevalence of BNT162b2 third (booster) dose in infliximab or vedolizumab treated patients with IBD. The secondary outcome evaluated whether the prevalence of BNT162b2 third (booster) dose differed based on type of COVID-19 vaccine, gender, age, type of biologic therapy and citizenship. Results: In total, 499 patients with IBD were included in this study. The median age was 34.5 years, and 60% had ulcerative colitis (UC). Among the study participants, 302 (60.5%) patients were vaccinated with BNT162b2, and 197 (39.5%) were vaccinated with ChAdOx1 nCoV-19. Of the total number of participants, 400 (80.2%) were receiving infliximab, and 99 (19.8%) were receiving vedolizumab. Overall, 290 (58.1%) of the included patients were willing to receive the third (booster) dose. Patients vaccinated with BNT162b2 were more likely to receive booster dose compared to patients vaccinated with ChAdOx1 nCoV-19 [201 (66.5%) vs 101 (33.5%), p = 0.014]. Infliximab-treated patients were more likely to receive booster dose compared to patients receiving vedolizumab [310 (77.5%) vs 62 (62.6%), p = 0.002]. There was no statistical difference in willingness to receive booster dose in terms of age, nationality, or gender. Conclusion: The percentage of patients with IBD willing or have received a third (booster) dose of BNT162b2 vaccine was lower compared to general population. In addition, patients who received two doses of BNT162b2 vaccines were more likely to receive a third (booster) dose compared to patients who received ChAdOx1 nCoV-19. Patients treated with infliximab were more likely to receive a third (booster) dose of COVID-19 vaccine.
COMPARATIVE ANALYSIS OF CHEMICAL COMPOSITION OF BUCHHOLZIA CORIACEA ETHANOL LEAF-EXTRACT, AQUEOUS AND ETHYLACETATE FRACTIONS

: The medicinal value of plants depends on their chemical constituents that provide a definite physiological action on the human body. Knowledge of chemical constituents of plant is necessary for the discovery of therapeutic agents of importance and their precursors. This work is aimed at evaluating and comparing the chemical composition of Buchholzia coriacea ethanol leaf-extract, aqueous and ethylacetate fractions of the ethanol leaf-extract. The phytochemical, mineral and vitamin constituents of the extract and fractions were analyzed using standard methods. Proximate composition of the dry leaves was also determined using standard method. Phytochemical constituents (mg/100g) in all samples were in the order of: Terpenoids>phenols>alkaloids>flavonoids>tannins>saponins>steroids>glycosides. Some phytochemicals were significantly (P<0.05) higher in the extract than fractions. The aqueous fraction contained vitamins B and C in significantly (P<0.05) higher amounts while ethylacetate fraction contained mainly vitamins A, D, E and K. The mineral compositions (mg/100g) in extract and fractions were in the order of Fe>Ca>Mg>K>P>Na>Cu while result of proximate analysis (%) the dry leaf was in the order of carbohydrates>protein>moisture>fibre>ash>fats. The acute toxicity study showed that the ethanol leaf-extract caused no death to the rats even at 5000 mg/kg body weight. The results show that Buchholzia coriacea contain some phytochemicals, vitamins and minerals in adequate concentration which could be responsible for the physiological activities of this plant. Therefore, this study provides scientific evidence for the use of this plant by rural dwellers in the management of various diseases. of Chemical of Buchholzia Coriacea Ethanol Leaf-Extract, Aqueous and Ethylacetate Fractions,
ANTI-OXIDANT AND ANTI-BUTYRYLCHOLINESTERASE ACTIVITY OF AN ETHANOLIC EXTRACT OF TINOSPORA CORDIFOLIA . EUROPEAN JOURNAL OF PHARMACEUTICAL AND MEDICAL RESEARCH

Cholinesterase inhibitors are the most sought after drugs for the symptomatic treatment of Alzheimer‟s disease. The present study, assessed the anti-oxidant and anti-butyrylcholinesterase property of an ethanolic extract of Tinospora cordifolia’s stem, which is an Ayurvedic plant traditionally used for its several medicinal properties. Our findings demonstrated that an ethanolic extract of Tinospora cordifolia’s stem significantly inhibited butyrylcholinesterase enzyme and showed maximum inhibition of 73.59±0.02% at 200μg/ml final concentration with IC 50 value of 37.41 μg/mL calculated from the percentage inhibition curve. The mechanism of enzyme inhibition demonstrated by Lineweaver-Burk plot showed competitive inhibition at higher concentration and mixed non-competitive mode of inhibition at lower concentration of plant extract. Antioxidant activity of the extract was assessed by Trolox equivalent antioxidant capacity assay and Ferric reducing ability of plasma assay, which suggested that this plant also possesses significant antioxidant property. The maximum ferrous sulphate equivalent and trolox equivalent values were found to be 1785.66 ± 0.060 μmol Fe 2+ E/g of dried sample and 0.72 ± 0.003 mmol Trolox E/g of dried sample respectively. It is concluded that this plant has potential in deriving lead compound for anti-butyrylcholinesterase and antioxidant property which might be beneficial in future for providing symptomatic relief for AD patients. leprotic, anti-diabetic, anti-spasmodic, anti-malarial, anti-inflammatory, anti-neoplastic, anti-arthritic, anti-stress, anti-allergic, anti-periodic, immunomodulatory, hepatoprotective and anti-oxidant activities. [23]
Importance of Large Intestine in Regulating Bile Acids and GLP-1 in Germ-free Mice.

It is known that (1) elevated serum bile acids (BAs) are associated with decreased body weight, (2) elevated GLP-1 levels can decrease body weight, and (3) germ-free (GF) mice are resistant to diet-induced obesity. The purpose of this study was to test the hypothesis that lack of intestinal microbiota results in more BAs in the body, resulting in increased BA mediated TGR5 signaling and increased serum GLP-1, as a mechanism of resistance of GF mice to diet-induced obesity. GF mice had 2-4 fold increased total BAs in serum, liver, bile, and ileum. Fecal excretion of BAs was 63% less in GF mice. GF mice had decreased secondary BAs and increased taurine-conjugated BAs, as anticipated. Surprisingly, there was an increase in non-12 α -OH BAs, namely β muricholic acid ( β MCA), ursodeoxycholic acid (UDCA) and their taurine conjugates in GF mice. Further, in vitro experiments confirmed that UDCA is a primary BA in mice. There were minimal changes in mRNA of FXR target genes in ileum (Fgf15, SHP, Ibabp), in liver (SHP, Lrh-1, Cyp7a1), and BA transporters (Asbt, Ost α , Ost β ) in ileum of GF mice. Surprisingly, there were marked increases in BA transporters in large intestine. Increased GLP-1 levels and gallbladder size were observed in GF mice, suggesting activation of TGR5 signaling. In summary, the GF condition results in increased expression of BA transporters in colon, resulting in an (1) increase in total BA concentrations in tissues, (2) change in BA composition to favor an increase in non-12 OH BAs, and (3) activation of TGR5 signaling with increased gallbladder size and GLP-1.
Oral Healthcare Measures to Improve Overall Health in Older Adults

The purpose of this paper is to guide the understanding of preventive oral health measures to improve overall health in older adults. Oral health is a key indicator of overall health, well-being, and quality of life, yet, oral health status among older adults has remained alarmingly poor. Common oral conditions include dental decay, periodontal disease, tooth loss, dry mouth, and malodor. The connection between oral and systemic health has been established and this relationship is affected by various interrelated factors which pose many threats to older adults’ health. Documented factors may range from chronic diseases, use of medications, individual lifestyle, decline in cognitive and physical functioning, access to care, to several social indicators of oral health. Dental disease and poor oral health are largely preventable through healthy lifestyle behaviors and effective management of chronic systemic diseases. A collaborative team approach is necessary to ensure that older adults receive comprehensive care appropriate for their complex medical and dental needs.
Phenotypic Correlation among Branch and Upper-Crown Stem Attributes in Douglas-Fir

To provide a basis for developing objective branch-habit selection criteria for tree breeding, phenotypic correlations were made among several branch character­ istics of 15-to 35-year-old relation analyses indicate that: (I) branch angle is not significantly associated with any variable except average cross-sectional area of branch bases; ( 2) of trees of similar stem volume those with fewer branches tend to have larger diameter branches; (3) of trees of similar stem volume those with fewer branches tend to have longer branches; ( 4) trees with fast height growth tend to have shorter branches when compared with slower growing trees of similar volume; ( 5) of trees of similar stem volume those growing faster in height tend to have smaller diameter branches; (6) tree age is not significantly correlated with any branch or stem characteristic; (7) stem volume is correlated with all measured variables except branch angle; (8) except for the close relationship between branch length and average cross-sectional area of branches, branch characteristics are generally very slightly associated. Path coefficient analysis suggests that variations in the four branching characteristics are directly associated with approxi­ mately 62 percent of the variation in stem volume.
Production of Lightweight Clay Bricks Using Polymer Wastes

- In this study, different percentages (2, 4, 6, 8, and 10% by weight of the soil) of chopped polymeric (plastic bottles with maximum particle size 2.36 mm and 1.18 mm in addition to rubber tires of 0.6 mm max particle size) wastes are incorporated with soil to produce lightweight clay bricks, to find the optimum percentage satisfying the requirements of bricks grade C using for non-structural walls (partitions). The effects of different types and percentages of the polymeric wastes on firing shrinkage, density, water absorption, compressive strength and thermal conductivity of the fired bricks were studied. Results indicate that it is possible to incorporate not more than 8% of chopped rubber tires or not more than 6% of chopped bottles to the clay soil to produce lightweight fired clay bricks satisfying the compressive strength and water absorption requirements for grade C of bricks (used for partitions) according to the Iraqi specification IQS 25/1988, in addition to reducing the thermal conductivity by 13-17% which is desirable as it will reduce the energy required for heating and cooling. Also, found that the size of the incorporated particles of plastic wastes in clay, used for bricks manufacturing, did not have a significant effect on the different studied properties of bricks. In addition to, the incorporation of chopped rubber tires, having smaller particles size and more sphere particles shape, produce fired clay bricks with more homogeneous pores distribution and smaller size compared with clay brick incorporating chopped plastic wastes having flaky shape and larger particles size, leading to produce clay brick with higher density and strength, with lower water absorption. As a total results, the incorporation different types of polymeric wastes (chopped plastic bottles with 2.36 and 1.18 max size and chopped rubber tires) with percentages (2, 4, 6, 8, and 10% by weight of soil) , cause the firing shrinkage and water absorption to increase by (0.6-20.2%) and (3-43.5%) respectively, while the density, compressive strength, and thermal conductivity decrease by (3.5-25.1%), (0.4-2.3%), and (2.1-31.9%) respectively with respect to the reference fired clay bricks, depending on the percentage, particles size, and type of the polymeric wastes addition.
Effect of Two Stocking Densities on Growth Performance, Litter Moisture Levels and Prevalence of Lameness in Broiler Chickens

This study assessed the effect of stocking density on growth performance, litter moisture levels and prevalence of lameness in broiler chickens. A total of 1500 1-day-old Cobb500 mixed-sex broiler chicks were randomly allocated to two stocking densities of 17 birds/m2 (high, HSD) and 11 birds/m2 (low, LSD) each with six replicate pens. Growth performance parameters were recorded at placement and then on weekly intervals. The walking ability of the birds was assessed on day 28 and 35 using the Kestin. , et al. (1992) gait scoring system. Bodyweight and daily gains were higher in HSD birds, while feed intake was higher in LSD birds (P > 0.05), and birds on the HSD had the highest FCR (P < 0.05). Stocking density had no significant effects on litter moisture levels, although the frequency and severity of lameness was higher in HSD birds and increased with age. The highest lameness severity rate was 30% and 3% for LSD birds with gait scores of 2 and 5 respectively; and 29% and 13.3% in HSD birds with gait scores of 3 and 5, respectively. It was concluded that reducing the number of birds per stocking density has benefits for leg health and feed conversion efficiency in broiler chickens.