Miracle-dz/UniFAR-FTUs huggingface dataset:
Consideration of whether a climatic regime shift has prevented the occurrence of a cold summer in northeast Eurasia since 2010

Does a warming world, where extremely hot summers are becoming more common, mean that cold summers will never again occur? It is crucial to know whether extremely cold summers are still possible, as such knowledge will significantly impact decisions regarding the further adaptation of crops to cold summers. Japan, which has suffered from many extremely cold summers, has managed past agricultural disruptions with emergency rice imports. In this paper, we show that a climate regime shift associated with the positive phase shift of the Arctic Oscillation occurred in 2010 in northeast Eurasia, making the occurrence of extremely cold summers highly unlikely as long as this new regime persists. In fact, Japan has not experienced a cold summer since 2010, while extremely hot summers have been frequent. Since 2010, a double jet structure with subtropical and polar jets has strengthened, and the polar jet has meandered further north of Japan, resulting in an upper tropospheric anticyclone. This anticyclone, which extends downwards and tilts southwards, reaches southern Japan and prevents cold advection of oceanic air over the cold Oyashio Current. The Okhotsk High, known as the leading cause of cold summers, has occurred frequently in recent years; however, cold summers have not occurred due to the tilting anticyclone. The recent warming of the Oyashio Current weakens cold advection. The Pacific-Japan pattern, known as a remote tropical influence, has been weakened. A better understanding of the regime shift will help us understand the tilting anticyclone and the associated extreme summers in northeast Eurasia.
La reformación de fósiles deformados demostrado en trilobites del piso Marianense (Cámbico inferior) del Sur de la Península Ibérica

espanolSe describen los metodos utilizados para producir imagenes aproximadas del estado original de fosiles, normalmente de simetria bilateral, pero encontrados deformados. Para desarrollar estos metodos se necesita un ordenador, poco trabajo y no mucho tiempo. En este trabajo se demuestra la reformacion de algunos trilobites deformados, todos ya publicados y en parte la reformacion se basa en imagenes de laminas ya publicadas, en la fauna de Vila Boim en Portugal y en las faunas de Sierra Morena en Andalucia (Alanis, Cala). Todos los ejemplares proceden de la parte media del Cambrico inferior, piso Marianiense. Los resultados son, entre otros, de un interes mas que regional: con toda probabilidad son la prueba que demuestra que Henningsmoen (1958) tenia razon cuando expreso la opinion de que Resserops resserianus R. & E. Richter, 1940 es un sinonimo de Perrector perrectus R. & E. Richter 1940, que es muy dudoso que Pagetiellus Lermontova, 1940 sea un sinonimo de Delgadella Walcott, 1912, y que el genero Judomia Lermontova, 1951 se encuentre en la fauna de Cala. EnglishMethods are described that allow to reform quickly and with a minimum of work with the help of a computer the original shape of deformed, formerly bilateral fossils. (For a short explanation see fig. 1). to show results of the methods, trilobites formerly published in deformed state are shown in reformed state, the process is partly based on the pictures formerly published. The specimens shown come from localities in the South of the Iberian peninsula (Vila Boim in Portugal and Alanis and Cala in the Sierra Morena, Andalucia, Southern Spain). Some results of more than local interest are that Henningsmoen (1958) was most probably right when he supposed that Resserops resserianus R. & E. Richter, 1940 is a symonym of Perrector perrectus R. & E. Richter 1940, that it is highly doubtful whether Pagetiellus Lermontova, 1940 is a synonym of Delgadella Walcott, 1912, and that the genus Judomia Lermontova, 1951 occurs in the fauna of Cala.
Vincristine-Induced Neuropathy in Patients Diagnosed with Solid and Hematological Malignancies: The Role of Dose Rounding

Background: Vincristine is a vital constituent of chemotherapeutic regimens. Vincristine-induced neuropathy is a challenging adverse effect that impacts quality of life and treatment course. The dose rounding of chemotherapies is a strategy that is commonly used in clinical practice. Nevertheless, the frequency of developed neuropathy in vincristine first-time users and the potential association with dose rounding remains elusive. Methods: A retrospective analysis was conducted on patients administered vincristine for the first time between 2016 and 2022 using the King Saud University Medical City (KSUMC) database. Patients were stratified into pediatric and adult groups. Neuropathy frequency, its association with demographic and clinical parameters, and the Impact of dose rounding were assessed using SPSS software version 28. Results: Approximately 34.6% of patients were diagnosed with neuropathy after vincristine administration. Autonomic neuropathy was common among affected adults and pediatric patients (55.1% and 56.1%, respectively), while cranial neuropathy was more frequent in pediatric patients. Higher BSA (p = 0.038) and Scr (p = 0.044) in the pediatric group, the presence of respiratory comorbidities (p = 0.044), and the use of azole antifungals (p < 0.001) in the adult group were significantly associated with neuropathy episodes. The rounding-up of vincristine doses was significantly associated with increased neuropathy occurrence (p < 0.001), while dose rounding-down was significantly associated with a decrease in neuropathy in both groups of patients (p < 0.001). Conclusions: Our findings demonstrate that autonomic neuropathy is the most common vincristine-related neuropathy, regardless of the patient’s age. Dose rounding is a significant determinant of vincristine-induced neuropathy in both groups. Further studies are needed to evaluate the variables that exacerbate or prevent neuropathy associated with the first-time use of vincristine.
Psychological, physical and sexual violence against brazilian women: a cross-section study

The objective was to characterize the notifications of urban violence against women, according to psychological, physical and sexual typologies. This is a cross-sectional, documentary, descriptive and analytical research, based on the notification forms of the Brazilian Notifiable Diseases Information System between the years 2014 and 2017, referring to a city in the Northeast. The independent variables were divided according to the most prevalent types of violence, while the dependent ones followed the characteristics suggested by the notification forms. The data were analyzed using the Chi-square and Fisher's Exact tests, with a significance level of 5%, in addition to calculating the Chance Ratio. RStudio was used as statistical software.447 notification forms were included, with the following prevalences being observed: psychological (80.1%), physical (39.2%), and sexual (21%), with a predominance of women with low educational level (<8 years of study), non-white race, without companions and heterosexuals. Most of the notifications pointed to the repetition of violence, occurring mainly at night, in homes and public roads, in the form of threats, and the use of body strength. Women are exposed to psychological, physical, and sexual violence, especially to the psychological form, possibly because they have a pattern intrinsically associated with other types.
Methane oxidation during the late Palaeocene thermal maximum

Carbon isotope records across the Latest Palaeocene Thermal Maximum (LPTM) display by a remarkable delta 13 C excursion of at least -2.5 per mil that occurred within 10X10 3 yrs. Thermal dissociation of marine gas hydrate and release of massive quantities of CH 4 to the exogenic carbon cycle appears to be the only plausible explanation for this geochemical perturbation. Three numerical simulations of the scenario are compared here. Each simulation involved release of 1.12X10 18 g of CH 4 over 10X10 3 yrs into the pre-industrial steady-state exogenic carbon cycle. The only difference between the simulations is whether CH 4 was oxidized in the atmosphere, deep Atlantic Ocean, or deep Pacific Ocean. Important conclusions from this work are that massive CH 4 release into any carbon reservoir will cause a negative delta 13 C excursion, increased atmosphere pCO 2 , elevated global surface temperature, and pelagic carbonate dissolution, but that the timing and magnitude of these responses depends on the location of CH 4 oxidation. Oxygen deficiency must also occur if significant quantities of CH 4 are oxidized in an ocean reservoir. Release and oxidation of massive quantities of CH 4 in the deep Atlantic Ocean is consistent with several observations from the geological record across the LPTM. However key data sets and additional modeling are needed before geochemical perturbations during this extraordinary time interval can be well understood.
Barriers and Facilitators to Cardiovascular Disease Prevention Following Hypertensive Disorders of Pregnancy in Primary Care: Cross-Sectional Surveys

Women with a history of hypertensive disorders of pregnancy (HDP) have an increased risk of cardiovascular disease (CVD). Guidelines recommend that women diagnosed with HDP should be advised of their increased CVD risk, have regular blood pressure monitoring by their general practitioner (GP), and adopt healthy lifestyle behaviours. However, within Australia, the current practice in primary health care is unknown. The aim of this study was to describe current practices, barriers, and facilitators to the provision of CVD preventative services for women after HDP in the primary care setting and to identify potential strategies to support GPs in providing recommended care. Separate cross-sectional online surveys were undertaken with 35 GPs and 105 women with a history of HDP. Surveys included both closed- and open-ended questions. Closed-ended questions were analysed using basic descriptive statistics, and open-ended questions were themed and tallied. The survey of GPs revealed that GPs are more likely to assess traditional CVD risk markers than lifestyle risk factors or HDP history. GPs identified a lack of resources and skills as barriers to providing CVD preventative care post-HDP. The survey with women after HDP revealed that women with a history of HDP are more likely to be assessed for blood pressure than lifestyle CVD risk factors, and that the women’s barriers to obtaining care included difficulty obtaining an appointment and time required for attending appointments. Strategies to improve CVD preventative care were consistent between surveys, where 70% of GPs and 59% of women chose ‘increasing women’s awareness of increased CVD risk’ and 67% of GPs and 55% of women chose ‘improving communication between hospitals and primary care’ as their preferred strategies. While the findings suggest that women with a history of HDP are receiving advice consistent with guidelines for traditional CVD risk markers, such as blood pressure, they are less likely to receive CVD preventative care for lifestyle or female-specific CVD risk factors.
Knowledge Spillover Effects and Employment Productivity in the Innovative Startups: Evidence from Italy

This paper analyzes the determinants and effects of technological catch-up and knowledge spillover effects on employment productivity in the Innovation Startup Segment in Italy using a sample of 260 Innovative Startup companies. Estimates indicate that regional specialization provides the highest potential for employment productivity gains, while higher levels of competition and higher regional diversity suppress the prospects for knowledge spillover effects to develop. Particularly, the analysis using the comprehensive sample of firms indicates the presence of forces leading to output per worker convergence at the national level, i.e., technological catch-up is present at the per-worker level; yet, the overall value of production convergence across regions is not present. We also detect the presence of Spatial Dependency in relation to the neighboring firms. That is, there is support for weak convergence across regions in favor of the Marshallian hypotheses. However, sectorial estimations for the Services, Information Technology, and Manufacturing sector indicate the presence of large differences in terms of technological catch-up effects.
LEVEL OF PAIN AND ANALGESICS TAKEN AFTER CESAREAN SECTION AND DIFFERENCES ACCORDING TO TYPE OF ANESTHESIA AND DEMOGRAPHIC FACTORS

SUMMARY The aim of this study was to investigate the level of pain and analgesic consumption in puerperas after cesarean section according to the type of anesthesia administered. This was a prospective study conducted at the Department of Obstetrics and Gynecology, Mostar University Hospital, in the period from September 2015 to June 2016. The study included 111 puerperas. Experimental group included 54 puerperas operated on under spinal anesthesia, while comparative group included 57 puerperas operated on under general anesthesia. Primary endpoints of the study were pain score and dose number of analgesics used. Input parameters of the study were age, gestational age, education, and place of residence. To determine the level of pain, visual analog scale for pain was used. Results showed that puerperas operated on under spinal anesthesia had significantly lower pain sensation (p=0.031) and less need for analgesic consumption in the postoperative period as compared to those operated on under general anesthesia (p=0.024). Increased age was associated with lower pain sensation (p=0.014) and need for analgesics (p<0.05). Higher level of education was associated with greater need for analgesics (p=0.016). Living in urban area was associated with greater pain sensation (p=0.023) and less need for analgesics (p<0.17). Spinal anesthesia for cesarean section resulted in less pain and less need for analgesics in the postoperative period compared to general anesthesia.
Inr tracking with face-to-face and phone app

Background: Warfarin has a narrow therapeutic window. Maintaining the patient’s international normalized ratio (INR) within a predefined therapeutic range is one of the main challenges of warfarin treatment. This study aimed to compare the INR values of patients followed by face-to-face and telephone applications. Methods: This study was designed as a randomized controlled trial. Twelve patients living in a distant place were assigned to the experimental group, and 12 patients living nearby and followed-up in the outpatient clinic were assigned to the control group. A Patient Information Form and the Adherence to Refills and Medications Scale were used to collect data. Results: There was no significant difference between the groups in terms of demographic and clinical characteristics except for age (P > .05). The INR values of 67% of the patients followed in the outpatient clinic and 72% of the patients followed with the application were in the therapeutic range. There was no significant difference between the groups and medication adherence was high in both groups (P > .05). Conclusion: In light of the findings of our study, which demonstrated that the INR levels of patients who were monitored both face-to-face and via a telephone application were within the same therapeutic range, it was concluded that the telephone application can be used to manage warfarin therapy.
Non-suicidal self-injury in young adults with and without borderline personality disorder: the role of emotion dysregulation and negative urgency

Non-suicidal self-injury (NSSI) is defined as self-inflicted pain, and it is used as a mechanism to alleviate psychological distress. Although NSSI is prevalent in Borderline Personality Disorder (BPD), it is also an increasing concern among college student populations. While emotion dysregulation and negative urgency are associated with NSSI, little is known about which dimensions specifically predict the motivations (NSSI-functions) and frequency of self-harm. The current study explored the relationship between emotion dysregulation, negative urgency, and NSSI in 86 young adults, divided into three groups: college students with NSSI, BPD patients with NSSI, and a healthy control group without NSSI. We conducted multiple regression analyses to predicted NSSI-functions and NSSI-frequency. Non-acceptance of emotions, a specific dimension of emotion dysregulation, uniquely predicted intrapersonal NSSI-functions (e.g., regulating distressing emotions), but not interpersonal NSSI-functions (e.g., communicating distress). Lastly, poor emotion regulation strategies predicted NSSI-frequency only in individuals with high negative urgency, that is, individuals who tend to act impulsively when experiencing negative emotions, but not in those with low negative urgency. Findings shed light on the underlying motivations for engaging in self-injury, and they reveal facets of emotion dysregulation relevant for NSSI treatment. La Autolesión No Suicida (ANS) se define como un dolor auto-infligido que se utiliza como un mecanismo para aliviar la angustia psicológica. Aunque ANS es común en el trastorno límite de la personalidad (TLP), también es un problema creciente en estudiantes universitarios. Si bien la desregulación emocional y la urgencia negativa están asociadas con ANS, poco se sabe sobre las dimensiones específicas que predicen la motivación (funciones) y la frecuencia de las autolesiones. Se exploró la relación entre la desregulación emocional, la urgencia negativa, y ANS en 86 adultos jóvenes, divididos en tres grupos: estudiantes universitarios con ANS, pacientes TLP con ANS y un grupo de control sano sin ANS. Realizamos análisis de regresión múltiple para predecir las funciones y frecuencia de ANS. La no aceptación de las emociones, una dimensión especifica de la desregulación emocional, predijo de manera única las funciones intrapersonales de ANS, pero no las funciones interpersonales. Por último, la falta de estrategias de regulación emocional predijo la frecuencia de ANS solo en individuos con una alta urgencia negativa, es decir, individuos que tienden a actuar impulsivamente cuando experimentan emociones negativas, pero no en aquellos con una baja urgencia negativa. Los hallazgos resaltan las motivaciones subyacentes a la autolesión y revelan facetas de la desregulación emocional relevantes para el tratamiento de ANS.
First Observation of a Baryonic B

We report the first observation of a baryonic B 0 s decay, B 0 s → p ¯ Λ K − , using proton-proton collision data recorded by the LHCb experiment at center-of-mass energies of 7 and 8 TeV, corresponding to an integrated luminosity of 3 . 0 fb − 1 . The branching fraction is measured to be B ð B 0 s → p ¯ Λ K − Þ þ B ð B 0 s → ¯ p Λ K þ Þ ¼ ½ 5 . 46 (cid:2) 0 . 61 (cid:2) 0 . 57 (cid:2) 0 . 50 ð B Þ (cid:2) 0 . 32 ð f s =f d Þ(cid:3) × 10 − 6 , where the first uncertainty is statistical and the second systematic, the third uncertainty accounts for the experimental uncertainty on the branching fraction of the B 0 → p ¯ Λ π − decay used for normalization, and the fourth uncertainty relates to the knowledge of the ratio of b -quark hadronization probabilities f s =f d .
Risk factors for death in hospitalized COVID-19 patients in Africa: A systematic review and meta-analysis

Background: The coronavirus disease 2019 has quickly spread worldwide since it first appeared in Wuhan, China, in late 2019. The most affected country in Africa was South Africa. This study aimed to identify the risk factors for death in hospitalized COVID-19 patients in Africa. Methods: We conducted a systematic review following the Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) guidelines. We searched articles from the following database: PubMed, Embase, Cochrane Library, Medline, and COVID-19 Research Database. We used Google Scholar for gray literature. The language used in this article was English. The last search was conducted on January 15, 2023. Pooled HRs, or ORs, and 95% confidence intervals, were calculated separately to identify the risk factors for death in hospitalized COVID-19 patients. Heterogeneity was assessed by Cochran’s Q statistic and the I2 test. The Egger test was used to assess publication bias. Subgroup analysis was performed to determine the source of heterogeneity. Data analysis was performed using Stata version 17. A P value < . 05 was considered significant. Results: A total of 16,600 articles were obtained from the database search; finally, 16 articles met the inclusion criteria and were eligible for data extraction. The analysis revealed that the pooled prevalence of mortality in hospitalized COVID-19 patients was 13.9%. Advanced age was a significant risk factor for death in hospitalized COVID-19 patients, with the pooled coronavirus mortality HR and OR being 3.73 (95% CI: 2.27–5.19) and 1.04 (95% CI: 1.02–1.06), respectively. In addition, male gender (pOR 1.23; 95% CI: 1.07–1.40), patients with diabetes mellitus (DM) (pOR 1.26; 95% CI: 1.01–1.51), hypertension (HTN) (pOR 1.56; 95% CI: 1.27–1.85), chronic kidney disease (CKD) (pHR 5.43; 95% CI: 0.18–10.67), severe or critical conditions (pOR 9.04; 95% CI: 3.14–14.94) had a significantly increased risk of coronavirus-related mortality. The main limitations of the present study stem from the predominant use of published studies, which could introduce publication bias. Conclusion: According to this study, advanced age, male gender, hypertension, diabetes mellitus, chronic kidney disease, and severe or critical condition were clinical risk factors associated with death outcomes in hospitalized COVID-19 patients in Africa.
Effect of ciprofol on swallowing function in patients undergoing painless gastrointestinal endoscopy

Background: Gastroscopy is one of the most commonly used diagnostic modalities for upper gastrointestinal disorders. This study compared the effect of ciprofol and propofol on swallowing function during painless gastroenteroscopy. Methods: This was a single-center, placebo-controlled randomized trial. Three hundred sixty-eight patients undergoing painless gastroscopy were included in this study and randomly divided into 2 groups: the propofol group (PRO group, n = 183) and the ciprofol group (CIP group, n = 185). Sufentanil, ciprofol, and propofol are used to anesthetize the patients, and the effects of different solutions on these patients are compared and analyzed. The patient’s general condition, vocal cord adduction reflex, dysphagia severity score, penetration and aspiration scale score, vital signs at different times, complications, recovery time (minutes), residence time in the resuscitation room (minutes), and adverse reactions were recorded. Results: During the examination, the incidence of severe swallowing dysfunction in CIP group was lower than that in PRO group (P < .05). The BP in CIP group was higher than that in PRO Group (P < .05). The HR of CIP group was lower than that of PRO Group (P < .05). SpO2 in CIP group was higher than that in PRO Group (P < .05). The recovery time of CIP group was longer than that of PRO Group, and the postanesthesia care unit stay time of PRO group was longer than that of CIP group(P < .05). The incidence of respiratory depression, hypotension and cough in CIP group was lower than that in PRO Group (P < .05). The incidence of injection pain in CIP group was lower than that in PRO Group (P < .05). Conclusion: Compared with propofol, ciprofol has less inhibition on swallowing function, less impact on hemodynamics, less respiratory depression, and less injection pain, which is more suitable for painless gastroscopy.