Miracle-dz/UniFAR-FTUs huggingface dataset:
Obesity and Non Alcoholic Fatty Liver Disease in Females in tertiary care Hospital

Background: Obesity is now recognized as a disease in its own right due to increase in morbidity and mortality. Obesity is strongly associated with metabolic disorders like diabetes hypertension cardiovascular disease and NAFLD. NAFLD is the most common liver disorder affecting the world and it is now considered as the most common cause of abnormal liver function tests. Aim: To study biochemical profile NAFLD in females and to study its association with obesity. Methodology: This is a descriptive study done in female patients who were diagnosed with fatty liver were enrolled in the study after detailed clinical, anthropometric study and lab work up. Focus was on biochemical and components of metabolic syndrome. Subjects were divided into two groups according to BMI as lean and obese NAFLD and various biochemical and metabolic parameters were compared. Results: This study concluded NAFLD is common in obese middle aged females.90% patients had truncal obesity. Two third of patients had metabolic syndrome with 90% having one component of metabolic syndrome. Biochemical and metabolic dysfunction were more significant in the obese NAFLD group showing that obesity plays a key role in the pathogenesis of NAFLD. Conclusion: Obesity is prevailing in rural Indian population. Lack of awareness and health care programmes directed toward identifying obesity as a disease on its own needs to be strengthened. Lifestyle modification and weight is the only effective treatment modality in liver diseases due to obesity.
The 21-cm bispectrum as a probe of non-Gaussianities due to X-ray heating

We present analysis of the normalized 21-cm bispectrum from fully-numerical simulations of intergalactic-medium heating by stellar sources and high-mass X-ray binaries (HMXBs) during the cosmic dawn. Ly-α coupling is assumed to be saturated, we therefore probe the nature of non-Gaussianities produced by X-ray heating processes. We find the evolution of the normalized bispectrum to be very different from that of the power spectrum. It exhibits a turnover whose peak moves from large to small scales with decreasing redshift, and corresponds to the typical separation of emission regions. This characteristic scale reduces as more and more regions move into emission with time. Ultimately, small-scale fluctuations within heated regions come to dominate the normalized bispectrum, which at the end of the simulation is almost entirely driven by fluctuations in the density field. To establish how generic the qualitative evolution of the normalized bispectrum we see in the stellar + HMXB simulation is, we examine several other simulations – two fully numerical simulations that include quasi-stellar object (QSO) sources, and two with contrasting source properties produced with the semi-numerical simulation 21CMFAST. We find the qualitative evolution of the normalized bispectrum during X-ray heating to be generic, unless the sources of X-rays are, as with QSOs, less numerous and so exhibit more distinct isolated heated profiles. Assuming mitigation of foreground and instrumental effects are ultimately effective, we find that we should be sensitive to the normalized bispectrum during the epoch of heating, so long as the spin temperature has not saturated by z≈19.
The topological basis of function in flow networks

The ability to reroute and control flow is vital to the function of many biological transport networks. By tuning the conductance of edges, many flow networks robustly control the propagation of inputs in order to achieve a wide variety of specific tasks. However, recent evidence suggests that network architectures used to achieve such tasks demonstrate significant design flexibility, blurring the relationship between structure and function. Here we seek to identify the structural features responsible for function in tuned networks. By adding and removing links, we optimize flow networks to perform a specific function, namely to achieve a minimum pressure difference along a chosen "target" edge when a pressure difference is applied to another predetermined "source" edge in the network. Using persistent homology, we show that networks tuned to perform such functions develop characteristic large-scale topological features that are similar for different networks that perform the same function, regardless of differences in the local link connectivity. These features correlate strongly with the tuned response, providing a clear topological relationship between structure and function.
Building a Cell House from Cellulose: The Case of the Soil Acidobacterium Acidisarcina polymorpha SBC82T

Acidisarcina polymorpha SBC82T is a recently described representative of the phylum Acidobacteriota from lichen-covered tundra soil. Cells of this bacterium occur within unusual saccular chambers, with the chamber envelope formed by tightly packed fibrils. These extracellular structures were most pronounced in old cultures of strain SBC82T and were organized in cluster-like aggregates. The latter were efficiently destroyed by incubating cell suspensions with cellulase, thus suggesting that they were composed of cellulose. The diffraction pattern obtained for 45-day-old cultures of strain SBC82T by using small angle X-ray scattering was similar to those reported earlier for mature wood samples. The genome analysis revealed the presence of a cellulose biosynthesis locus bcs. Cellulose synthase key subunits A and B were encoded by the bcsAB gene whose close homologs are found in genomes of many members of the order Acidobacteriales. More distant homologs of the acidobacterial bcsAB occurred in representatives of the Proteobacteria. A unique feature of bcs locus in strain SBC82T was the non-orthologous displacement of the bcsZ gene, which encodes the GH8 family glycosidase with a GH5 family gene. Presumably, these cellulose-made extracellular structures produced by A. polymorpha have a protective function and ensure the survival of this acidobacterium in habitats with harsh environmental conditions.
A Review of Gender in the 21st Century: Fighting Dangerous Stereotypes

Gender is a condition of being a male or female. Much of the time, it is generally defined by social and social distinctions rather than biological differences. Gender stereotype generalizations are currently present for life. Even though a disposition to mess up a part of the present gender stereotypes-related platitude occurs due to late unreasonably being insufficient to deal with the issues that comprise gender lays out. Whereas generally, females wind up being casualties of gender stereotypes, males experience the adverse effects of criminal offenses associated with maleness. Women's works tend to be predominantly traditional and less prestigious, while personalities are predominantly shy and passive characterization. Women are primarily engaged in domestic and in-house jobs, while men are more likely to exist in specialist facilities. There appears to be a systematic under-representation of women, regardless of whether we consider the text or images. The study shows a point of view for the effect of gender stereotypes and the progression of female stereotypes in the 21st century.
Generalized compactness limit from an arbitrary viewing angle

A $\gamma$-ray source must have a limited optical depth to pair production. This simple condition, called compactness, implies that gamma-ray bursts (GRBs) must involve a highly relativistic motion ($\Gamma \gtrsim 100$) giving the first and most important clue on their nature. So far, this condition has been discussed under the assumption that the $\gamma$-ray sources are viewed on-axis, that is, by an observer within the beaming cone of the relativistic source. Recently, following the detection of the weak short GRB 170817A, an extensive interest arose in the possibility that some $\gamma$-ray sources are viewed off-axis. We generalize here the compactness formalism for an arbitrary viewing angle taking several possible opacity processes and $\gamma$-ray spectra into account. We find that for a given observables (peak luminosity, temporal variability, and spectra) the minimal Lorentz factor, $\Gamma_{\rm min}$, is obtained, as expected, for an on-axis observer. More remarkably we find that compactness dictates also a maximal viewing angle, $\theta_{\rm max} \simeq 1/2\Gamma_{\rm min}$. Our limit implies for regular GRBs a very small allowed viewing angle ($\lesssim10^{-2}\,\rm rad$), making it extremely unlikely that they are viewed off-axis. For GRB 170817A we confirm earlier results that rule out the possibility that the observed $\gamma$-rays were seen by an on-axis observer as a regular short GRB. The short GRB 150101B was also suggested to be an off-axis event. We show that its maximal viewing angle $\lesssim0.05\,\rm rad$, which is inconsistent with the off-axis model. Finally we show that for low luminosity GRBs, compactness does not exclude by itself an off-axis model, but when combined with other consideration this option is strongly disfavored.
Design of a Forest Fire Early Alert System through a Deep 3D-CNN Structure and a WRF-CNN Bias Correction

Throughout the years, wildfires have negatively impacted ecological systems and urban areas. Hence, reinforcing territorial risk management strategies against wildfires is essential. In this study, we built an early alert system (EAS) with two different Machine Learning (ML) techniques to calculate the meteorological conditions of two Colombian areas: (i) A 3D convolutional neural net capable of learning from satellite data and (ii) a convolutional network to bias-correct the Weather Research and Forecasting (WRF) model output. The results were used to quantify the daily Fire Weather Index and were coupled with the outcomes from a land cover analysis conducted through a Naïve-Bayes classifier to estimate the probability of wildfire occurrence. These results, combined with an assessment of global vulnerability in both locations, allow the construction of daily risk maps in both areas. On the other hand, a set of short-term preventive and corrective measures were suggested to public authorities to implement, after an early alert prediction of a possible future wildfire. Finally, Soil Management Practices are proposed to tackle the medium- and long-term causes of wildfire development, with the aim of reducing vulnerability and promoting soil protection. In conclusion, this paper creates an EAS for wildfires, based on novel ML techniques and risk maps.
Abundant Z-cyanomethanimine in the interstellar medium: paving the way to the synthesis of adenine

We report the first detection in the interstellar medium of the Z-isomer of cyanomethanimine (HNCHCN), an HCN dimer proposed as precursor of adenine. We identified six transitions of Z-cyanomethanimine, along with five transitions of E-cyanomethanimine, using IRAM 30m observations towards the Galactic Center quiescent molecular cloud G+0.693. The Z-isomer has a column density of (2.0$\pm$0.6)$\times$10$^{14}$ cm$^{-2}$ and an abundance of 1.5$\times$10$^{-9}$. The relative abundance ratio between the isomers is [Z/E]$\sim$6. This value cannot be explained by the two chemical formation routes previously proposed (gas-phase and grain surface), which predicts abundances ratios between 0.9 and 1.5. The observed [Z/E] ratio is in good agreement with thermodynamic equilibrium at the gas kinetic temperature (130$-$210 K). Since isomerization is not possible in the ISM, the two species may be formed at high temperature. New chemical models, including surface chemistry on dust grains and gas-phase reactions, should be explored to explain our findings. Whatever the formation mechanism, the high abundance of Z-HNCHCN shows that precursors of adenine are efficiently formed in the ISM.
A GINGA observation of FO Aqr: discless accretion and multiple emission components

The analysis of a 32-hr GINGA observation of the intermediate polar FO Aqr is presented. The power spectrum of the X-ray light curve, constructed using the one-dimensional CLEAN algorithm, indicates strong modulation at the binary-orbital, white-dwarf spin and beat periods. The asymmetry between the positive and negative orbital sidebands of the spin frequency implies that the beat modulation cannot be caused by an amplitude modulation of the spin pulse and must be intrinsic to the source. It is demonstrated that the beat is unlikely to be due to a reflection effect and as a result can only arise in a discless accretion geometry in which the majority of the accretion flow switches from one magnetic pole of the white dwarf to the other every half a beat cycle. This naturally produces an apparent orbital modulation of the X-ray spin pulse, which is seen clearly in these data
The MASSIVE Survey. VI. The Spatial Distribution and Kinematics of Warm Ionized Gas in the Most Massive Local Early-type Galaxies

We present the first systematic investigation of the existence, spatial distribution, and kinematics of warm ionized gas as traced by the [O ii] 3727 Å emission line in 74 of the most massive galaxies in the local universe. All of our galaxies have deep integral-field spectroscopy from the volume- and magnitude-limited MASSIVE survey of early-type galaxies with stellar mass (MK < −25.3 mag) and distance D < 108 Mpc. Of the 74 galaxies in our sample, we detect warm ionized gas in 28, which yields a global detection fraction of 38 ± 6% down to a typical [O ii] equivalent width limit of 2 Å. MASSIVE fast rotators are more likely to have gas than MASSIVE slow rotators with detection fractions of 80 ± 10% and 28 ± 6%, respectively. The spatial extents span a wide range of radii (0.6–18.2 kpc; 0.1–4Re), and the gas morphologies are diverse, with 17/28 ≈ 61 ± 9% being centrally concentrated, 8/28 ≈ 29 ± 9% exhibiting clear rotation out to several kiloparsecs, and 3/28 ≈ 11 ± 6% being extended but patchy. Three out of four fast rotators show kinematic alignment between the stars and gas, whereas the two slow rotators with robust kinematic measurements available exhibit kinematic misalignment. Our inferred warm ionized gas masses are roughly ∼105 M⊙. The emission line ratios and radial equivalent width profiles are generally consistent with excitation of the gas by the old underlying stellar population. We explore different gas origin scenarios for MASSIVE galaxies and find that a variety of physical processes are likely at play, including internal gas recycling, cooling out of the hot gaseous halo, and gas acquired via mergers.
Antifungal Activity of Biosynthesized Silver Nanoparticles (AgNPs) against Aspergilli Causing Aspergillosis: Ultrastructure Study

Currently, nanoparticles and nanomaterials are widely used for biomedical applications. In the present study, silver nanoparticles (AgNPs) were successfully biosynthesized using a cell-free extract (CFE) of Bacillus thuringiensis MAE 6 through a green and ecofriendly method. The size of the biosynthesized AgNPs was 32.7 nm, and their crystalline nature was confirmed by XRD, according to characterization results. A surface plasmon resonance spectrum of AgNPs was obtained at 420 nm. Nanoparticles were further characterized using DLS and FTIR analyses, which provided information on their size, stability, and functional groups. AgNPs revealed less cytotoxicity against normal Vero cell line [IC50 = 155 μg/mL]. Moreover, the biosynthesized AgNPs exhibited promising antifungal activity against four most common Aspergillus, including Aspergillus niger, A. terreus, A. flavus, and A. fumigatus at concentrations of 500 μg/mL where inhibition zones were 16, 20, 26, and 19 mm, respectively. In addition, MICs of AgNPs against A. niger, A. terreus, A. flavus, and A. fumigatus were 125, 62.5, 15.62, and 62.5 μg/mL, respectively. Furthermore, the ultrastructural study confirmed the antifungal effect of AgNPs, where the cell wall’s integrity and homogeneity were lost; the cell membrane had separated from the cell wall and had intruded into the cytoplasm. In conclusion, the biosynthesized AgNPs using a CFE of B. thuringiensis can be used as a promising antifungal agent against Aspergillus species causing Aspergillosis.
A STUDY ON THE GROWTH AND YIELD OF EXOTIC MUNGBEAN IN A COASTAL SALINE SOIL WITH DIFFERENT FERTILIZER DOSES

The coastal area of Bangladesh lying in the sou thern deltaic zones of the country covers about 3.2 million hectares. About 0.833 million hectares of land in the coast is affected by varying degrees of salinity. Major limitations of saline soils are high salinity of soil, river and ground water; ionic and osmotic imbalance; low to very low soil fertility and scarcity of quality irrigation water during drought season. A field experiment was conducted in the coastal saline soil of the Khulna district. The area is mostly under monocropped local T. aman practices having cropping sequence of Fallow-Fallow-T. aman. Topsoil, river, pond and ground water salinity in this area ranges from 3.8-13.8, 1.35-14.9, 2.6-6.7 and 3.5-8.3 dS/m respectively during January to May. At the advent of summer, the topsoil initiates the cracking and extends to a few cm during the peak period both horizontally and vertically. Soil is incapable of retaining irrigation or rainwater as per crop demand at the beginning of the season. Frequent irrigation with pond water increases the germination (>20%) of exotic BINA Mung-2. BINA Mung-2 can exist at soil salinity (ECe ) of 6.5-9.8 dS/m and with irrigated water (ECw) of 3.0-4.8 dS/m up to 45 days after sowing during drought period. Soil test based fertilizer dose responded better growth and yield than other recommended doses.
Characterization of the lesser known Korean seerfish Scomberomorus koreanus (Kishinouye, 1915) (Scombriformes: Scombridae) in Indian waters

Abstract Scomberomorus koreanus was originally described from a single specimen from the west coast of Korea. In 1964 the species was synonymized with S. guttatus during the systematic review of the scombroid fishes of India. Subsequently, S. koreanus was discovered in Palk Bay in 1976, confirming its first record from India and the Indian Ocean. Since then, no such detailed taxonomic studies have been undertaken for the species along the Indian coast. Although the species is distributed in the Indo-West Pacific region and forms a commercially important fishery in part of its range, S. koreanus is poorly known and very limited taxonomic studies have been carried out in detail which usually results in misidentifications at field level. The present morpho-genetic investigation and previous molecular study by the authors confirmed the occurrence of the species in the coastal waters of both the Bay of Bengal and the Arabian Sea. The exact characteristics of S. koreanus are detailed here, and their comparison was made here with the related species S. guttatus found in the northern part of the east coast of India, based on a thorough morphological study, including the radiographs of 13 fresh specimens (334–588 mm FL), colour photographs of S. koreanus collected in 2019–2021 and DNA barcoding.
Constraining cosmic scatter in the Galactic halo through a differential analysis of metal-poor stars

We present the abundances of Li, Na, Mg, Al, Si, Ca, Sc, Ti, V, Cr, Mn, Co, Ni, Zn, Sr, Y, Zr, and Ba in a wide metallicity range ($-2.8 \le$ [Fe/H] $\le -1.5$). Using the differential technique allowed us to obtain an unprecedented low level of scatter in our analysis, with standard deviations as low as 0.05 dex, and mean errors as low as 0.05 dex for [X/Fe]. By expanding our metallicity range with precise abundances from other works, we were able to precisely constrain Galactic chemical evolution models in a wide metallicity range ($-3.6 \le$ [Fe/H] $\le -0.4$). The agreements and discrepancies found are key for further improvement of both models and observations. We also show that the LTE analysis of Cr II is a much more reliable source of abundance for chromium, as Cr I has important NLTE effects. These effects can be clearly seen when we compare the observed abundances of Cr I and Cr II with GCE models. While Cr I has a clear disagreement between model and observations, Cr II is very well modeled. We confirm tight increasing trends of Co and Zn toward lower metallicities, and a tight flat evolution of Ni relative to Fe. Our results strongly suggest inhomogeneous enrichment from hypernovae. Our precise stellar parameters results in a low star-to-star scatter ($0.04$ dex) in the Li abundances of our sample, with a mean value about $0.4$ dex lower than the prediction from standard Big Bang Nucleosynthesis; we also study the relation between lithium depletion and stellar mass, but it is difficult to assess a correlation due to the limited mass range. We find two blue straggler stars, based on their very depleted Li abundances. One of them shows intriguing abundance anomalies, including a possible zinc enhancement, suggesting that zinc may have been also produced by a former AGB companion.
Epidemiological and pathological screening of suspected cases of contagious bovine pleuropneumonia in Yola Modern Abattoir, Adamawa State Nigeria

Contagious bovine pleuropneumonia is an important infectious disease of cattle caused by Mycoplasma mycoides subsp. mycoides and a major constraint to cattle production in sub-Saharan Africa. This study was aimed to identify pathological and histopathological lesions identified in cattle tentatively diagnosed with CBPP at Yola Modern Abattoir, Adamawa State. A total of 9,750 cattle were examined at post-mortem for a period of six months, 110 (1.13%) had lesions suggestive of CBPP out of which seventeen (17) were randomly selected and processed for histopathology based on standard laboratory protocols. Based on sex, CBPP lesion was observed more in female 63 (1.06%) than in the male 47 (1.24%). Whereas, CBPP lesions was observed highest in White Fulani breed 68 (1.14%) followed by Cross breeds 23 (91.16%) and Sokoto Gudali 19 (1.74%) and lowest in Red Bororo 10 (1.36%). There was insignificant statistical association (P>0.05) between CBPP lesions and sex and breed of cattle sampled. Age distribution of CBPP lesion was observed higher in cattle between ages of 4-7 years 79 (1.16%), followed by cattle of 1-3 years 28 (1.15%) and least in cattle less than 1 year 3 (0.60%) with significant statistical difference (P<0.05) between the age groups. Histopathology lesions observed include severe congestion of pulmonary blood vessel in all the lung tissues and fibrin exudation into inter-alveolar spaces with almost all the alveoli collapsed. The bronchiolar epithelium was observed to be thickened, hyperplastic and folded, with a considerable quantity of edematous fluid and numerous inflammatory cells seen in the lumen. In conclusion, this study had demonstrated the presence of CBPP lesions in cattle in the study area. Therefore, serological screening of all cattle, stamping out policies and aggressive annual vaccination campaigns are thus recommended in the study area.
De Sitter Breaking in Field Theory

I argue against the widespread notion that manifest de Sitter invariance on the full de Sitter manifold is either useful or even attainable in gauge theories. Green's functions and propagators computed in a de Sitter invariant gauge are generally more complicated than in some noninvariant gauges. What is worse, solving the gauge-fixed field equations in a de Sitter invariant gauge generally leads to violations of the original, gauge invariant field equations. The most interesting free quantum field theories possess no normalizable, de Sitter invariant states. This precludes the existence of de Sitter invariant propagators. Even had such propagators existed, infrared divergent processes would still break de Sitter invariance.