Miracle-dz/UniFAR-FTUs huggingface dataset:
Poly (Methyl Methacrylate)-Containing Silver-Phosphate Glass Exhibits Potent Antimicrobial Activity without Deteriorating the Mechanical and Biological Properties of Dental Prostheses

Poly (methyl methacrylate) (PMMA) is a commonly used denture material with poor antimicrobial effects. This study investigated the antimicrobial effects of PMMA-containing silver-phosphate glass. We fabricated a novel material comprising PMMA-containing silver-phosphate glass. Then, microhardness, flexural strength, and gloss unit were analyzed. Antimicrobial activity against Streptococcus mutans and Candida albicans was investigated. Colony-forming units were counted, and antimicrobial rates were measured. Biocompatibility tests were performed using a colorimetric MTT assay for evaluating cell metabolic activity. The microhardness, flexural strength, and gloss unit of the experimental groups (with silver-phosphate glass) were not significantly different from those of the control group (no silver-phosphate glass) (P > 0.05), which showed clinically valid values. With increasing proportions of silver-phosphate glass, the antimicrobial activity against the two microorganisms increased (P < 0.05). Furthermore, S. mutans showed more than 50% antimicrobial activity in 4%, 6%, and 8% experimental groups, C. albicans showed more than 50% antimicrobial activity in 6% and 8% groups, and a statistically significant difference in antimicrobial activity was observed compared to the control (P < 0.05). The cell viability of the experimental groups was not significantly different from that of the control group (P > 0.05). Both control and experimental groups showed approximately 100% cell viability. These results suggest that silver-phosphate glass is a promising antimicrobial material in dentistry.
Real-time detection method for welding parts completeness based on improved YOLOX in a digital twin environment

Detection of the completeness of welding parts for automotive body-in-white welding relies mainly on both artificial and sensor detection. Due to a lack of intelligent methods, it is difficult to achieve accurate detection. This paper presents a new intelligent detection method based on improved YOLOX in a digital twin (DT) environment. Firstly, to address the problem of insufficient real samples, virtual datasets are made to increase data volume by using DT technology and realize the fusion of virtuality and reality. Secondly, an improved MobileNetv1 network is designed as the feature extraction network for YOLOX. Additionally, the original convolution is replaced by depthwise separable convolution blocks for reducing computational burden and improving detection speed. Experimental results show that the number of parameters is 59.1% less than that of the original model and the detection speed is increased from 36 to 50 frames s–1. Meanwhile, mean average precision increases by 1.42% and 2.76%, respectively, under two different overlaps.
First Results from the ISO-IRAS Faint Galaxy Survey

We present the first results from the ISO-IRAS Faint Galaxy Survey (IIFGS), a program designed to obtain ISO observations of the most distant and luminous galaxies in the IRAS Faint Source Survey by filling short gaps in the ISO observing schedule with pairs of 12 μm ISOCAM and 90 μm ISOPHOT observations. As of 1997 October, over 500 sources have been observed, with an ISOCAM detection rate over 80%, covering over 1.25 deg2 of sky to an 11.5 μm point-source completeness limit of approximately 1.0 mJy (corresponding to a ~10 σ detection sensitivity). Observations are presented for nine sources detected by ISOPHOT and ISOCAM early in the survey for which we have ground-based G- and I-band images and optical spectroscopy. The ground-based data confirm that the IIFGS strategy efficiently detects moderate-redshift (z = 0.11-0.38 for this small sample) strong emission line galaxies with L60 μm ≳ 1011 L☉; one of our sample has L60 μm > 1012 L☉ (H0 = 75 km s-1 Mpc-1, Ω = 1). The infrared-optical spectral energy distributions are comparable to those of nearby luminous infrared galaxies, which span the range from pure starburst (e.g., Arp 220) to infrared QSO (Mrk 231). Two of the systems show signs of strong interaction, and four show active galactic nucleus (AGN)-like excitation; one of the AGNs, F15390+6038, which shows a high excitation Seyfert 2 spectrum, has an unusually warm far- to mid-infrared color and may be an obscured QSO. The IIFGS sample is one of the largest and deepest samples of infrared-luminous galaxies available, promising to be a rich sample for studying infrared-luminous galaxies up to z ~ 1 and for understanding the evolution of infrared galaxies and the star formation rate in the universe.
Physical properties of mine drainage sediment according to depth in settling ponds

ABSTRACT In order to effectively manage the sludge in the settling ponds, it is necessary to understand the physical properties of the sludge according to the depth in the pond. A new sludge sampling device and method was proposed in this study. Sludge was sampled at three depths in four facilities in South Korea, and the water content, particle size, density, composition, and viscosity of the sediment according to the depth were measured and evaluated. These results can be used to predict the shape of sediment and the lifetime of the settling pond, and to plan and effectively implement sediment removal.
Cold DCO(+) cores and protostars in the warm Rho Ophiuchi cloud

The decrease of DCO(+) abundance with elevation of a cloud's T(K) is used to identify a cluster of a dozen of the coldest, youngest dense cores embedded in the L1688, L1689, and L1709 clouds in the Rho Ophiuchi complex. Most of the cores in L1688 have T(K) = 12-14 K, about half that indicated by CO throughout L1688. Ten cold dust shell, protostellar IR point sources are embedded within these cores. Not every DCO(+) core contains a protostar, but every protostar with a steep spectral index is found in close association with DCO(+) emission. The rotational axes for all of the Rho Oph DCO(+) cores are parallel to the ambient magnetic field, regardless of whether a core is elongated parallel or perpendicular to the direction of the magnetic field. In the Taurus complex the ambient magnetic field is perpendicular to the axes of the major filaments and will inhibit further concentration of material. 53 refs.
Further Investigation of the Impact of Idealized Continents and SST Distributions on the Northern Hemisphere Storm Tracks

AbstractBuilding on previous studies of the basic ingredients of the North Atlantic storm track (examining land–sea contrast, orography, and SST), this article investigates the impact of Eurasian topography and Pacific SST anomalies on North Pacific and Atlantic storm tracks through a hierarchy of atmospheric GCM simulations using idealized boundary conditions in the Hadley Centre HadGAM1 atmospheric circulation model.The Himalaya–Tibet mountain complex is found to play a crucial role in shaping the North Pacific storm track. The northward deflection of the westerly flow around northern Tibet generates an extensive pool of very cold air in the northeastern tip of the Asian continent, which strengthens the meridional temperature gradient and favors baroclinic growth in the western Pacific. The Kuroshio SST front is also instrumental in strengthening the Pacific storm track through its impact on near-surface baroclinicity, while the warm waters around Indonesia tend to weaken it through the impact on barocl.
Investigating Partially Discordant Results in Phase 3 Studies of Aducanumab

Objectives Efficacy and safety results from the EMERGE (NCT02484547) and ENGAGE (NCT02477800) phase 3 studies of aducanumab in early Alzheimer’s disease (AD) have been published. In EMERGE, but not in ENGAGE, high-dose aducanumab demonstrated significant treatment effects across primary and secondary endpoints. Low-dose aducanumab results were consistent across studies with non-significant differences versus placebo that were intermediate to the highdose arm in EMERGE. The present investigation examined data from EMERGE and ENGAGE through post-hoc analyses to determine factors that contributed to discordant results between the high-dose arms of the two studies. Design EMERGE and ENGAGE were 2 phase 3, randomized, double-blind, placebo-controlled, parallel-group studies. Setting EMERGE and ENGAGE were 2 global multicenter studies involving 348 sites in 20 countries. Participants Participants in EMERGE and ENGAGE were aged 50 to 85 years and had mild cognitive impairment or mild AD dementia with confirmed amyloid pathology. The randomized and dosed population (all randomized patients who received at least one dose of study treatment) included 1638 patients in EMERGE and 1647 in ENGAGE. Intervention In EMERGE and ENGAGE, participants were randomized to receive low- or high-dose aducanumab or placebo (1:1:1) once every 4 weeks. Measurements In this paper, 4 areas were investigated through post-hoc analyses to understand the discordance in the high-dose arms of the EMERGE and ENGAGE studies: baseline characteristics, amyloid-related imaging abnormalities, non-normality of the data, and dosing/exposure to aducanumab. Results Post-hoc analyses showed that outcomes in the ENGAGE high-dose group were affected by an imbalance in a small number of patients with extremely rapid progression and by lower exposure to the target dose of 10 mg/kg. These factors were confounded and present in early enrolled patients but were not present in later-enrolled patients who were randomized to the target dosing regimen of 10 mg/kg after titration. Neither baseline characteristics nor amyloid-related imaging abnormalities contributed to the difference in results between the high-dose arms. Conclusions Results were consistent across studies in later enrolled patients in which the incidence of rapidly progressing patients was balanced across treatment arms.
Prevalence of tongue-tie and evaluation of speech sound disorder in young children

Purpose: Tongue-tie is a common congenital abnormality whose effect on speech sound disorders is controversial. The first purpose of this study was to determine the prevalence of tongue-tie in Persian speaking children aged 3–6 years. Second, compare the speech sound errors of children with tongue-tie with those of children without tongue-tie.Methods: 487 (206 female, 281 male) children aged 3–6 years were recruited for this study. Descriptive statistics were used to determine the prevalence of tongue-tie. Fisher’s exact test was performed to compare the speech sound errors of children with and without tongue-tie.Results: The prevalence of tongue-tie in children was 14.9%. These children showed a statistically significant difference in the production of the /s/, /z/, and /l/ sounds in both the initial and final positions of the word and the /t/ sound in the initial position of the word.Conclusions: While it is theoretically expected that the tongue-tie affects the production of anterior sounds, our clinical study shows speech sound disorder in only a limited number of cases. Therefore, it seems that surgical intervention on tongue-tie for sole purpose of speech improvement should be performed cautiously.
The Stability of a Developing Thermal Front in a Porous Medium. II Nonlinear Evolution

We consider the instability of the unsteady thermal boundary that is caused by suddenly raising the temperature of the lower boundary of an otherwise cold saturated porous medium. In particular, we focus attention on strongly nonlinear two-dimensional convection. A comprehensive set of results is presented which shows the effects of varying the amplitude of the disturbance, its wave number, and the time at which the disturbance is introduced into the developing thermal boundary layer. We indicate, in detail, how the evolution of the instabilities with time is affected by nonlinearity and how the characteristics of that evolution are changed from those that arise in linearized theory. We also determine when linearized theory is inadequate to describe the global features of the evolution, such as the re stabilisation of convection. Copyright © 2006 Begell House, Inc.
HST/WFPC2 Observations of Warm Ultraluminous Infrared Galaxies

We present new high-resolution B- and I-band images of a nearly complete sample of nine "warm" (f25/f60 > 0.2), ultraluminous infrared galaxies (ULIGs) obtained with the Wide Field Planetary Camera of the Hubble Space Telescope (HST). The HST images clearly reveal the presence of tidal tails and other features associated with merging galaxies. All of the warm ULIGs show evidence of complex structures such as dust lanes and spiral features in their inner few kiloparsecs. Additionally, they show compact, blue "knots" of star formation (between 4 and 31 knots per object) that appear similar to those seen in more nearby merger systems. Spectral synthesis modeling is used to estimate mean upper age limits and masses: the median upper age limit for the knots in individual galaxies is ~3 × 108 yr (ranging from ~107 to 1 × 109 yr), and the range of knot masses is ~105-109 M☉. We also argue that these starburst knots cannot be significant contributors to the extremely high bolometric luminosity of these galaxies. Additionally, each object contains one or two knots whose luminosity and color are implausible in terms of star formation; we identify these as putative active nuclei. These observations are consistent with the hypothesis that warm ULIGs may represent a critical transition stage in the evolution of ULIGs into optical quasi-stellar objects.
Arterial supply to the rabbit male genital organs

The improvement of veterinary care has prolonged the lifespan of rabbits, and the number of rabbits suffering from age-related, male genital disorders may increase in the near future. This could result in increased opportunities for male genital surgery, requiring knowledge of their arterial anatomy, which, however, has not been sufficiently studied. Therefore, the arteries supplying the genitals were observed in 20 male New Zealand White rabbits. The testis was supplied by the testicular artery originating from the abdominal aorta. The right testicular artery usually emerged at a more cranial level than the left artery (65%). The testicular artery encircled the testis in the sagittal plane and bifurcated (95%) or trifurcated (5%) at the caudal extremity of the testis before entering the parenchyma. The epididymis was supplied by the epididymal branches, either from only the testicular artery (75% of the right and 80% of the left halves) or from both the testicular artery and aorta. The deferent duct was supplied in all halves by the dorsal and ventral branches of the deferential artery, which usually arose from the umbilical artery. The accessory genital glands were supplied by the dorsal branch of the deferential artery and the prostatic artery. The latter, which emerged from the internal iliac artery, exhibited 3 branching types. The most frequent type (55% of the right and 45% of the left halves) had 3 branches supplying the accessory genital glands. These findings will help improve rabbit genital surgery.
Electromagnetic levitation apparatus for diffraction investigations on the short-range order of undercooled metallic melts

One of the most fundamental questions in the research field of undercooled melts is concerned with the structural short-range order of melts, because the short-range order decisively influences the physical properties and the solidification behaviour of undercooled liquids. Following the pioneering work of Frank in 1952, an icosahedral short-range order should be energetically favoured in undercooled metallic melts. Although this hypothesis is nearly 50 years old, direct experimental information on the short-range order prevailing in undercooled metallic liquids has only been available for a short time. This is mainly due to the fact that undercooled melts are a metastable state of matter which is difficult to conserve for times long enough to perform diffraction experiments of good quality. In this paper an apparatus is described that allows us to investigate the short-range order of undercooled metallic melts by combining the undercooling technique of electromagnetic levitation with the diffraction techniques of elastic neutron scattering and energy dispersive x-ray diffraction (EDXD) with synchrotron radiation. The diffraction experiments were performed with this device at the Institut Laue-Langevin (ILL) and at the European Synchrotron Radiation Facility (ESRF). These experiments provided the first direct experimental proof of an icosahedral short-range order prevailing in a great variety of undercooled melts of pure metals and alloys forming quasicrystalline or polytetrahedral phases. The icosahedral short-range order exists already at temperatures, T, above the melting temperature, TL, and becomes more pronounced if the melts are undercooled.
Remarkable long-term changes in the small Magellanic Cloud Wolf-Rayet system HD 5980

In this paper we report the remarkable changes which occured in the Small Magellanic Cloud W-R system HD5980 = AB5 between 1978 and 1991. Within this timescale, there has been a systematic enhancement (by factors of 2-10 depending on the line) in the equivalent widths of all emission lines, and a change in the relative strengths of N III, N IV, and N V lines. Currently, the W-R spectrum is more typical of a WN6 star than a WN3 or WN4, as it was originally classified. The terminal speed of the wind has diminished by approximately 600 km/s, while the system has brightened in the visual by 0.45 mag. The UV (1850 A) continuum changed by less than 0.13 mag. The change from WN3 or WN4 to WN6 is unprecedented. The system appears to be composed at least three stars: two WNs in mutual 19.266 day orbit and an O-type supergiant. We propose that the changes observed in HD 5980 are related to an increase in wind density of one (or both? ) of the W-R components, where the brighter WN6 component will dominate the W-R spectrum after the change, and we speculate that this modification of the wind structure is driven by tidal interaction induced by a possible current periastron passage of the third component in the system.
Whether technology and Human Resources competencies supported by periodic audits can improve Village Fund Financial Accountability

The purpose of this study has an orientation to analyze the effect of the use of Information Technology, Human resources competence, and periodic audits that are moderated in the realization of Financial Accountability Bottopenno village fund in Majauleng District Wajo. In order to achieve the formulated research orientation, this study uses quantitative research with descriptive paradigm. Sources of data used are primary data obtained through the distribution of questionnaires and secondary data obtained through the internet and district data. Methods of analysis exist using multiple linear regression and Moderated Regression Analysis (MRA). The results revealed that the use of Information Technology and Human Resource competence has a positive and significant influence on the financial accountability of the village fund. Periodic audits can also be a moderator between the positive and significant influence of information technology utilization and Human Resource competence on financial accountability of village funds.
What Firm-Specific and Macroeconomic Determinants of Financial Structure Affect Transport and Storage Companies from Selected European Countries?

: A number of indicators can be assessed for a company’s financial health, with indebtedness indicators being one of the important ones. The formation of the financial structure is influenced by a huge number of factors. The subject of this research is the indebtedness of companies in the Transportation and storage industry. The companies come from the V4 countries, Austria, Bulgaria, Slovenia, and Romania, between 2010 and 2018. In total 25,246 companies are analysed according to their size for medium and large companies. The aim of the research is to find out whether profitability, liquidity, asset structure, non-debt tax shield, GDP growth rate, reference interest rate, and inflation rate affect the level of total, long-term and short-term debt. The main finding is that corporate debt is significantly affected (measured by the value of coefficients) by non-corporate determinants and specifically the development of the reference interest rate. However, if we look at the most numerous determinants, it is profitability. Companies in the selected industry should focus primarily on the various forecasts within the external environment of the company and include them in their analyses when financing their activities.
Asymptotic relative efficiency of wald tests in measurement error models

In this paper, asymptotic relative efficiency (ARE) of Wald tests for the Tweedie class of models with log-linear mean, is considered when the aux¬iliary variable is measured with error. Wald test statistics based on the naive maximum likelihood estimator and on a consistent estimator which is obtained by using Nakarnura's (1990) corrected score function approach are defined. As shown analytically, the Wald statistics based on the naive and corrected score function estimators are asymptotically equivalents in terms of ARE. On the other hand, the asymptotic relative efficiency of the naive and corrected Wald statistic with respect to the Wald statistic based on the true covariate equals to the square of the correlation between the unobserved and the observed co-variate. A small scale numerical Monte Carlo study and an example illustrate the small sample size situation.
Absence of Scaffold Protein Tks4 Disrupts Several Signaling Pathways in Colon Cancer Cells

Tks4 is a large scaffold protein in the EGFR signal transduction pathway that is involved in several cellular processes, such as cellular motility, reactive oxygen species-dependent processes, and embryonic development. It is also implicated in a rare developmental disorder, Frank–ter Haar syndrome. Loss of Tks4 resulted in the induction of an EMT-like process, with increased motility and overexpression of EMT markers in colorectal carcinoma cells. In this work, we explored the broader effects of deletion of Tks4 on the gene expression pattern of HCT116 colorectal carcinoma cells by transcriptome sequencing of wild-type and Tks4 knockout (KO) cells. We identified several protein coding genes with altered mRNA levels in the Tks4 KO cell line, as well as a set of long non-coding RNAs, and confirmed these changes with quantitative PCR on a selected set of genes. Our results show a significant perturbation of gene expression upon the deletion of Tks4, suggesting the involvement of different signal transduction pathways over the well-known EGFR signaling.