Miracle-dz/UniFAR-FTUs huggingface dataset:
Transcriptional Analysis on Resistant and Susceptible Kiwifruit Genotypes Activating Different Plant-Immunity Processes against Pseudomonas syringae pv. actinidiae

Pseudomonas syringae pv. actinidiae (Psa), a bacterial pathogen, is a severe threat to kiwifruit production. To elucidate the species-specific interaction between Psa and kiwifruit, transcriptomic-profiles analyses were conducted, under Psa-infected treatment and mock-inoculated control, on shoots of resistant Maohua (MH) and susceptible Hongyang (HY) kiwifruit varieties. The plant hormone-signal transduction and plant–pathogen interaction were significantly enriched in HY compared with MH. However, the starch and sucrose metabolism, antigen processing and presentation, phagosome, and galactose metabolism were significantly enriched in MH compared with HY. Interestingly, the MAP2 in the pathogen/microbe-associated molecular patterns (PAMPs)-triggered immunity (PTI) was significantly up-regulated in MH. The genes RAR1, SUGT1, and HSP90A in the effector-triggered immunity (ETI), and the NPR1 and TGA genes involved in the salicylic acid signaling pathway as regulatory roles of ETI, were significantly up-regulated in HY. Other important genes, such as the CCRs involved in phenylpropanoid biosynthesis, were highly expressed in MH, but some genes in the Ca2+ internal flow or involved in the reactive oxygen metabolism were obviously expressed in HY. These results suggested that the PTI and cell walls involved in defense mechanisms were significant in MH against Psa infection, while the ETI was notable in HY against Psa infection. This study will help to understand kiwifruit bacterial canker disease and provide important theoretical support in kiwifruit breeding.
Development of face-to-face and face-to-back ultra-fine pitch Cu-Cu hybrid bonding

We have developed the novel fabrication process that has realized the robust ultra-fine pitch, 1 μm pitch, wafer level face-to-face Cu-Cu hybrid bonding. For the stable electrical connection between upper Cu pads and lower Cu pads, wet process, ECD process and CMP process were examined to protrude Cu connection pads steadily and we have verified that our advanced process integration has achieved high electrical yields. Moreover, the 1. 4μm pitch level Cu-Cu hybrid bonding has been successfully introduced into face-to-back bonding interface. We have developed the novel wafer thinning process to minimize total thickness variation (TTV) of Si and roundness of wafer edge, at the same time.
The intra-industry trade dynamics in CEE countries: The role of trade agreements

This paper investigates the impact of regional trade agreements (RTAs) on the development of intra-industry trade (IIT) for eight Central and Eastern Europe countries (CEE) from 1997 to 2019. The aim of the paper is to compare and explain the possible heterogeneous impact of different RTAs on IIT across countries while controlling for differences in development levels between economic integration member states. Our analysis is based on country-product level data obtained from UN Comtrade. The main hypothesis of the paper is that the CEFTA and EU integration agreements have a highly positive effect on IIT in comparison with other RTAs. However, the scope of the impact varies across countries, primarily depending on the economic development asymmetries that are in this paper proxied by the GDP per capita. We developed and estimated an augmented structural gravity model using Pseudo-Poisson Maximum Likelihood Estimator. The main contribution of our paper is the inclusion of the FTA-economic development gap interaction term, which enabled us to enrich the empirical findings of the research. Our results show that the main hypothesis holds, but also that an increase in economic asymmetries between integration members negatively affects IIT, thus indicating potentially increasing trade adjustment costs for new member states of an integration. These results go in favor of EU pre-integration and post-integration policies that have the goal of diminishing the economic development gap between future and present integration members.
Exploring the Impact of Gender Difference on 3-6 Years Old Children’s Physical Activity Levels

Several studies have shown that children’s physical activity levels (PAL) are not sub-optimal, however, PAL is critical to children’s development. The purpose of this study is to test the hypothesis that whether there is a significant gap between boys and girls on PAL. The gender is ignored in the previous research was remedied in this study. Quantitative methods are employed to collect primary data on PAL in children aged 3-6 years. This study has implications in terms of theory, methodology, and practice, for researchers, practitioners, and parents in the preschool education field.
Management practices matter: understanding volunteers’ memories at the Youth Olympic Games*

ABSTRACT Purpose: This study aims to understand the memories of Youth Olympic Games (YOG) volunteers long after their participatory experiences and how the volunteer managerial practices constructed those memories. Methodology: Focus groups were used in combination with document analysis to further investigate how the volunteer management practices at the Nanjing 2014 construct the current volunteer memory of YOG experience. Three focus groups with a total of 14 participants were conducted in September 2018. Findings: Involvement- and interaction-related practices have been identified as essential factors in shaping memories, while tangible souvenirs are vital in retrieving these memories in the long term. It confirms that volunteers remembered self-generated and entertaining activities best, referring to the generation and humor effect of memory. Practical implications: Results have implications for informing future volunteer management practices in nurturing young individuals’ memory, which is particularly important for events that aim to empower young people far in the long term as a volunteer legacy. Research contribution: The application of the memory concept brings new insights into the theoretical foundations of mega sport volunteering studies. Further, this research contributes to an essential subject on the Youth Olympic Games by adopting the Asian case of Nanjing 2014 four years after the event conclusion.
The Portrayal of Women in Persuasive Advertisement: Semiotic Analysis of Deeja Cosmetic TV Commercial

The purpose of advertising is to effectively promote items or services so that people will buy them. Repetition of viewing to the advertisement for the desired product strengthens purchasing habits. However, advertisements frequently contain sexual and objectification of women. This study aims to analyse the ethical decision-making that occurs due to the information presented using the micro and macro text of beauty product commercials. Thus, this study employs a social semiotics model to comprehend emotional strategies and contentious images by examining the process, effects, and consequence of ethical judgment; they function as mechanisms for propagating specific social culture and ethical values. Despite several past research studies attempting to discover beauty products' ideology using social semiotic analysis, no significant progress has been made to explore the studies on local beauty products. Therefore, a semiotic analysis will be used to obtain the data, as it is the most effective way of comprehending how meaning is produced in text. This research exclusively focuses on how Deeja Cosmetic advertisements employ female portrayal and the specific creative strategies the advertisers utilise to persuade and control their customers. From the analysis, women were presented inferiorly relative to their personalities and roles. At the same time, the findings indicate advertisers portray women as an object of desire to persuade the audience for the brand recall. Keywords: Advertisement, ethics, women objectification, sex appeal, female figure.
The Term Structure of Interest Rates in a Heterogeneous Monetary Union

We build a no-arbitrage model to analyze the term structure of sovereign interest rates in a heterogeneous monetary union. We consider a union of two countries, Core and Periphery, in which Core issues default-free sovereign bonds, while Periphery issues defaultable bonds. The possibility of rollover crises in the peripheral bond market implies a default probability that depends on bond supply net of central bank holdings. We derive an a ne bond price solution, despite a time-varying risk of partial default, and we decompose yields into term premium and credit risk components. Calibrating the model to Germany and Italy, we nd that the model replicates well the asymmetric reaction of the two countries' yield curves to the ECB's pandemic emergency purchase program (PEPP) announcement. The exibility in PEPP purchases over time and across jurisdictions is found to have substantially enhanced the program's impact on the aggregate area-wide yield curve. *This draft replaces an earlier version entitled Assessing the e ectiveness of the ECB's pandemic purchase program: a term structure modelling approach . The views expressed in this manuscript are those of the authors and do not necessarily represent the views of Banco de España or the Eurosystem. The authors are grateful for helpful comments from Ricardo Gimeno, Walker Ray, and Valery Charnavoki, and also from seminar participants at the ECB, the Banco de España, the 3rd Spanish Macroeconomics Network workshop, the 24th Central Bank Macroeconomic Modelling Workshop, the 3rd ILMA conference (HSE Moscow), and at the 2021 meetings of the SCE, CEBRA, and EEA. All remaining errors are ours.
Effect of Nano Fertilizer on Growth, Yield and Quality of Okra (Abelmoschus esculentus)

The present investigation was conducted to study the effect of nano fertilizer in the growth yield and quality of okra (Abelmoschus esculenthus). The experiment was carried out at the instructional farm of ICAR- Krishi Vigyan Kerndra, Pathanamthitta, Kerala, during the year 2021. The experiment was laid out in randomized block design with three replications. Ten different treatments were carried out with different combinations of fertilizers. The result obtained with treatment T2 (Soil application of 50% recommended dose of fertilizers as conventional fertilizer + 50% recommended dose of nano N as foliar application, nano P&K as soil application) was recorded the best among in all combination of conventional fertilizer NPK and nano NPK in term of growth, yield attribute and quality parameters like plant height 120.21 cm, number of leaves per plant 83.99, number of branches per plant 3.62, days to first harvesting 46.97, pod length 12.72cm, pod width 1.65cm, number of pods per plant 29.23, average of pod weight 12.67g, pod yield per plant 370.39g, pod yield per plot 8.89kg, pod yield 131.69q ha-1and TSS 2.930Brix. The highest cost benefit ratio 3.59 was also observed in T2 (Soil application of 50% RDF as conventional fertilizer + 50% recommended dose of nano N as foliar application, nano P&K as soil application).
Clinical Implication of Circulating Tumor Cells Expressing Epithelial Mesenchymal Transition (EMT) and Cancer Stem Cell (CSC) Markers and Their Perspective in HCC: A Systematic Review

Simple Summary One of the major problems regarding hepatocellular carcinoma (HCC) is the development of metastasis and recurrence, even in patients with an early stage. Recently, circulating tumor cells (CTCs) enumeration has been intensively studied as a diagnostic and prognostic biomarker in HCC. Nevertheless, increasing evidence suggests the role of metastasis-associated CTC phenotypes, including epithelial–mesenchymal transition (EMT)-CTCs and circulating cancer stem cells (CCSCs). We performed a systematic review to investigate the correlation of different CTC subtypes with HCC characteristics and their prognostic relevance to clinical outcomes. A preliminary meta-analysis found that CTC subtypes had prognostic power for predicting the probability of early recurrence. This study highlights the potential of CTC subtyping analysis as a biomarker for HCC management and provides information on metastasis-associated CTCs for a deeper molecular characterization of specific CTC subtypes. Abstract Circulating tumor cells (CTCs) play a key role in hematogenous metastasis and post-surgery recurrence. In hepatocellular carcinoma (HCC), CTCs have emerged as a valuable source of therapeutically relevant information. Certain subsets or phenotypes of CTCs can survive in the bloodstream and induce metastasis. Here, we performed a systematic review on the importance of epithelial–mesenchymal transition (EMT)-CTCs and circulating cancer stem cells (CCSCs) in metastatic processes and their prognostic power in HCC management. PubMed, Scopus, and Embase databases were searched for relevant publications. PRISMA criteria were used to review all studies. Twenty publications were eligible, of which 14, 5, and 1 study reported EMT-CTCs, CCSCs, and both phenotypes, respectively. Most studies evaluated that mesenchymal CTCs and CCSCs positivity were statistically associated with extensive clinicopathological features, including larger size and multiple numbers of tumors, advanced stages, micro/macrovascular invasion, and metastatic/recurrent disease. A preliminary meta-analysis showed that the presence of mesenchymal CTCs in pre- and postoperative blood significantly increased the risk of early recurrence. Mesenchymal-CTCs positivity was the most reported association with inferior outcomes based on the prognosis of HCC recurrence. Our finding could be a step forward, conveying additional prognostic values of CTC subtypes as promising biomarkers in HCC management.
CCID_A_196412 267..275

Mohammadreza Sobhan Ghazal Gholampoor Farzin Firozian Younes Mohammadi Maryam Mehrpooya 1Psoriasis Research Center, Department of Dermatology, Farshchian Hospital, Hamadan University of Medical Sciences, Hamadan, Iran; 2Department of Clinical Pharmacy, School of Pharmacy, Hamadan University of Medical Sciences, Hamadan, Iran; 3Medicinal Plants and Natural Products Research Center, Hamadan University of Medical Sciences, Hamadan, Iran; 4Department of Pharmaceutics, School of Pharmacy, Hamadan University of Medical Sciences, Hamadan, Iran; 5Modeling of Noncommunicable Diseases Research Center, School of Public Health, Hamadan University of Medical Sciences, Hamadan, Iran Purpose: Seborrheic dermatitis (SD) is a chronic inflammatory skin disorder that mainly affects areas rich in sebaceous glands, such as the scalp. Although the exact cause of SD is not clearly understood, it seems that skin colonization with Malassezia fungus and the inflammatory responses of the immune system to this fungus play an important role in the pathology of SD. Recently a growing body of evidence has shown anti-inflammatory and anti-fungal effects of statins. Thus, this study aimed to evaluate the efficacy of topical atorvastatin in the treatment of scalp SD. Patients and methods: In this double-blind, clinical trial, 86 patients with mild-tomoderate scalp SD were divided into either atorvastatin (n=45) or betamethasone groups (n=41) by block randomization method. In addition to the ketoconazole 2% shampoo (3 times per week), the atorvastatin group received atorvastatin 5% lotion and the betamethasone group received betamethasone 0.1% lotion daily for 4 weeks. The SD severity of each patient was determined by Symptom Scale of Seborrheic Dermatitis (SSSD) at baseline and 4 weeks after treatment. Also, the patient’s satisfaction of the treatment and adverse effects were investigated through individual reporting. Results: After 4 weeks of treatment, the score of SD severity decreased significantly in both groups, while changes of SSSD score from baseline to the fourth week of treatment were comparable in the two groups (P-value=0.476). Regarding patient’s satisfaction of the treatment, results demonstrated the non-inferiority of atorvastatin as compared to betamethasone. Topical atorvastatin was also well-tolerated in almost all patients. Conclusion: Although preliminary, the results of the present study showed that topical atorvastatin has a comparable effect to topical betamethasone and can be considered as an alternative therapeutic modality in the treatment of scalp SD. However, these results need to be confirmed in future studies while taking into consideration the improvement of topical statin formulations.
An investigation of implementation, adoption and use of technology for enhancing students' CoreLife Skills in a vocational institute : a case study informed by actor-network theory

With the increasing emphasis on developing graduate employability skills, termed as CoreLife Skills in the United Arab Emirates (UAE), and growing use of technology in education; this research investigates the assemblage of CoreLife Skills through technological innovation in a vocational education and training (VET) institute in the UAE. Further, the research explores the influence of teachers and students' technology adoption on the technological innovation. Using a case study research strategy, the project draws on the concepts of the sociology of translation from Actor-Network Theory as both a methodological and analytical tool to inform multiple data collection methods: interviews, observation, review of documents and technological artefact. The research unfolds the socio-material assemblages using existing frameworks: Levels of Teaching Innovation (LoTi), HEAT (higher order thinking, engaged learning, authentic learning and technology use), and the unified theory of acceptance and use of technology (UTAUT). The research stirred the development of technology enhanced learning and CoreLife Skills development (TEL-CSD) framework for effective integration of technology to enhance students’ CoreLife Skills. Cases of technological innovation underpinned by the TEL-CSD framework suggest that technology integration at LoTi Level 3 or above resulting in the generation of HEAT at the corresponding level, did enhance students’ CoreLife Skills. Based on the findings, two conclusions were drawn: CoreLife Skills cannot be developed independently of general learning and cognitive skills, and technology alone cannot promote CoreLife Skills. The findings suggest that teachers and students’ technology adoption influenced mobilisation of allies and sustainability of the actor-network. This also provides tools for critiquing the proposed universality of the UTAUT as a technology adoption model, since influences such as power dynamics, personal characteristics, technical limitations and glitches are absent in the UTAUT. This research thereby demonstrates the usefulness of actor-network approaches in reconsidering and revising existing models in the field of education.
Financial Linkages in European Equity and Debt Markets

This paper studies financial market linkages in Europe throughout the lifetime of the Euro. In considering the national equity and sovereign debt markets of the seven biggest economies in Europe, I find important developments in cross-country as well as cross-asset linkages. There is evidence for a revival of country-specific risk, causing a differentiation between riskier “peripheral” Euro area countries (Italy, Spain) and presumably safer “core” countries (Germany, the Netherlands). As a consequence, a “flight to safety” phenomenon can be observed. Interestingly, there is evidence that these “flight to safety” capital flows partially revert themselves in periods of relative stability in European financial markets.
Characterization of particle

The method for determining the charge of at least one test particles, comprising the steps of applying one of the current or voltage passing through the aperture connecting the two chambers, the chamber is at least partially filled with the electrolyte, at least one test particles includes the steps of changing and measuring steps which is adapted to float in at least one electrolyte chamber, the other current or voltage passing through the aperture, the pressure differential between the two chambers, And determining the charge based on the measurement of current or voltage.
the return-to-work self-efficacy

return-to-work self-efficacy questionnaire Objective The 19-item return-to-work self-efficacy (RTWSE-19) scale is a new self-report measure intended to assess workers’ beliefs of their current ability to resume normal job responsibilities following pain onset. The aim of this study was to evaluate the factor structure, internal consistency, and predictive and concurrent validity of RTWSE-19 among workers with acute low-back pain. Methods Patients (N=399, 59% male, mean age 37 years) consulting for acute, work-related low-back pain completed an original 28-item version of the new scale along with concurrent measures of pain, functional limitation, activity avoidance, workplace physical demands, and pain catastrophizing. The assessment was repeated at visit 2, and work limitations and duration of sickness absence were assessed by questionnaire at 3-month follow-up. Exploratory factor analysis (principal component analysis with varimax rotation) was used to assess content validity of the scale, and scores were compared to concurrent pain measures and with disability outcomes at 3 months. 28 floor effects. Mean item scores ranged from 4.9 (“reducing physical workload”) to 8.3 (“describing injury to supervisor”). The exploratory factor analysis supported three underlying factors (eigenvalue >1.0): (i) meeting job demands; (ii) modifying job tasks; and (iii) communicating needs to others. Internal consistency (alpha) for the three scales were 0.98, 0.92, and 0.81, respectively. At visit 2, self-efficacy scores improved for “meeting job demands” and “modifying job tasks”, but not for “communicating needs to others”. After controlling for pain and functional limitation, both sickness absence and persistent work limitations were predicted by self-efficacy assessed at visit 2 (P<0.05), but self-efficacy assessed at visit 1 did not predict sickness absence. Conclusions The RTWSE-19 is a new measure with adequate reliability and validity to measure the confidence of workers to meet job demands, modify job tasks, and communicate needs to co-workers and supervisors. When assessed 1–2 weeks after pain onset, the scale is predictive of disability outcomes.
EFFECT OF OIL CONCENTRATION ON THE MICROENCAPSULATION OF FLAXSEED OIL BY SPRAY DRYING

: This work aimed to evaluate the influence of emulsion composition, as well as its associated properties (stability, viscosity and droplet size), on the microencapsulation of flaxseed oil by spray drying, using gum Arabic as wall material. Emulsions were prepared with a fixed total solid content (30% w/w), with different oil concentrations (10, 20, 30 and 40%). The increase in the oil concentration led to the formation of emulsions with larger droplets and lower viscosity, and, consequently, in the production of particles with higher surface oil and higher lipid oxidation.