Miracle-dz/UniFAR-FTUs huggingface dataset:
A novel bidirectional modular multilevel inverter utilizing diode‐based bidirectional unit

Multilevel inverters have many applications, such as the grid integration of photovoltaic cells, FACTSs devices, electric vehicles, variable speed drives, and smart grids. In this paper, a new bidirectional diode‐based unit is proposed for a symmetric single‐phase modular inverter topology that can achieve high output levels by using a small number of switching and circuit devices. The basic structure can generate nine‐level voltage with only nine IGBTs and two diodes. Another advantage of the proposed topology is the utilization of a half‐bridge module to change the voltage polarity and the low number of its voltage sources. Additionally, the proposed topology can be used as the cascaded structure with different approaches to select the value of voltage sources. The power losses are discussed for the proposed basic module. A comparison has been made with some recently presented topologies to compare the proposed multilevel inverter and demonstrate its superiority. The comparison is performed for the basic module and its generalized structure. In this paper, the pulse width modulation technique is utilized to achieve a voltage waveform with low harmonic content. The proposed basic structure has an efficiency of 58.98% in 5KW power. Finally, the operation of the proposed basic module is simulated, and the laboratory prototype results confirm the accuracy of the simulation results.
Preferences for HIV prevention strategies among newly arrived Asian-born men who have sex with men living in Australia: A discrete choice experiment

The HIV epidemic in Australia is changing with higher risk for HIV among newly-arrived Asian-born men who have sex with men (MSM) compared to Australian-born MSM. We evaluated the preferences for HIV prevention strategies among 286 Asian-born MSM living in Australia for <5 years. A latent class analysis uncovered three classes of respondents who were defined by their preferences: “PrEP” (52%), “Consistent condoms” (31%), and “No strategy” (17%). Compared to the “No strategy” class, men in the “PrEP” class were less likely to be a student or ask their partner for their HIV status. Men in the “Consistent condoms” class were more likely to get information about HIV from online, and less likely to ask their partner for their HIV status. Overall, PrEP was the preferred HIV prevention strategy for newly arrived migrants. Removing structural barriers to access PrEP can accelerate progress toward ending HIV transmission.
Flow visualization using reflective flakes

Abstract The pattern in an image of flow visualizations using reflective flakes stems from their non-uniform orientation rather than their spatial accumulation. It is shown, based on the assumption that flakes are infinitely thin elliptic discs without inertia, that the temporal evolution of their orientations is identical to that for infinitesimal material surface elements. In general, bright regions in a visualized image are the superposition of those where the flake (i.e. the material surface element) orientation is isotropic and those where flakes tend to align in the direction for which the incident rays are reflected into the line of sight. A non-trivial example of the visualization of a steady flow in a precessing sphere is given to verify these conclusions.
The risks of low hemoglobin deferral in a large retrospective cohort of plasmapheresis donors and the influence factors of return for a subsequent donation in China

Background According to the Technical Operation Procedures for Plasmapheresis Collection Station (2019) in China, plasmapheresis donors with low hemoglobin (Hb) levels (men <12.0 g/dL; women <11.0 g/dL) were deferred for at least 2 weeks. The purpose of this retrospective study was to survey the demographic characteristics of plasmapheresis donors with low Hb deferral (LHD) and identify at-risk LHD donors, so as to enhance donor safety and improve donation service management. Methods From 2018 to 2020, a multi-center study involving plasmapheresis donors from 18 plasmapheresis centers in three provinces (Sichuan, Yunnan and Hunan) of China was conducted. Donor demographics (age, sex) and donation information (date of donation, first-time donors vs. repeat donors, the number of lifetime donations, the number of donations in the last 12 months, and whether the LHD donor returned for a subsequent donation) were collected. The Cochran-Mantel-Haenszel method was used to explore the risk factors for LHD while adjusting for the different provinces. Logistic regression analysis was used to investigate the factors influencing the return for a subsequent donation after LHD. Results A total of 497,039 plasmapheresis donors were included. Female donors’ LHD rate was 0.15% on average, while male donors’ LHD rate was 0.01%. Female donors aged 41–50 years old (OR: 2.276, 95% CI [1.333–3.887], p = 0.002) were more likely to experience LHD temporarily than those aged 18–30 years old. For female donors, compared with donations in the winter, they had a higher risk for LHD in the summer (OR: 2.217, 95% CI [1.670–2.943], p < 0.001), spring (OR: 2.402, 95% CI [1.806–3.196], p < 0.001), and fall (OR: 2.002, 95% CI [1.500–2.673], p < 0.001). Among the LHD donors, those who had donated more frequently in the past were more likely to return for a subsequent donation (p = 0.012). Conclusions Female donors were at a higher risk of LHD, particularly between the ages of 41 and 50. A clear seasonal pattern in the rate of LHD was observed. In the winter, the risk of LHD was the lowest; thus, it was advised to recruit plasmapheresis donors throughout the winter and to make the required adjustments for recruitment measures during other seasons. The number of previous donations was correlated with the return rate after LHD. Our observations could have practical implications for plasmapheresis donor management.
Computerized Block Games for Automated Cognitive Assessment: Development and Evaluation Study

Background Cognitive assessment using tangible objects can measure fine motor and hand-eye coordination skills along with other cognitive domains. Administering such tests is often expensive, labor-intensive, and error prone owing to manual recording and potential subjectivity. Automating the administration and scoring processes can address these difficulties while reducing time and cost. e-Cube is a new vision-based, computerized cognitive assessment tool that integrates computational measures of play complexity and item generators to enable automated and adaptive testing. The e-Cube games use a set of cubes, and the system tracks the movements and locations of these cubes as manipulated by the player. Objective The primary objectives of the study were to validate the play complexity measures that form the basis of developing the adaptive assessment system and evaluate the preliminary utility and usability of the e-Cube system as an automated cognitive assessment tool. Methods This study used 6 e-Cube games, namely, Assembly, Shape-Matching, Sequence-Memory, Spatial-Memory, Path-Tracking, and Maze, each targeting different cognitive domains. In total, 2 versions of the games, the fixed version with predetermined sets of items and the adaptive version using the autonomous item generators, were prepared for comparative evaluation. Enrolled participants (N=80; aged 18-60 years) were divided into 2 groups: 48% (38/80) of the participants in the fixed group and 52% (42/80) in the adaptive group. Each was administered the 6 e-Cube games; 3 subtests of the Wechsler Adult Intelligence Scale, Fourth Edition (WAIS-IV; Block Design, Digit Span, and Matrix Reasoning); and the System Usability Scale (SUS). Statistical analyses at the 95% significance level were applied. Results The play complexity values were correlated with the performance indicators (ie, correctness and completion time). The adaptive e-Cube games were correlated with the WAIS-IV subtests (r=0.49, 95% CI 0.21-0.70; P<.001 for Assembly and Block Design; r=0.34, 95% CI 0.03-0.59; P=.03 for Shape-Matching and Matrix Reasoning; r=0.51, 95% CI 0.24-0.72; P<.001 for Spatial-Memory and Digit Span; r=0.45, 95% CI 0.16-0.67; P=.003 for Path-Tracking and Block Design; and r=0.45, 95% CI 0.16-0.67; P=.003 for Path-Tracking and Matrix Reasoning). The fixed version showed weaker correlations with the WAIS-IV subtests. The e-Cube system showed a low false detection rate (6/5990, 0.1%) and was determined to be usable, with an average SUS score of 86.01 (SD 8.75). Conclusions The correlations between the play complexity values and performance indicators supported the validity of the play complexity measures. Correlations between the adaptive e-Cube games and the WAIS-IV subtests demonstrated the potential utility of the e-Cube games for cognitive assessment, but a further validation study is needed to confirm this. The low false detection rate and high SUS scores indicated that e-Cube is technically reliable and usable.
The effect of perceived stress on depression in college students: The role of emotion regulation and positive psychological capital

Introduction College students have become a high prevalence group and vulnerable group of depression. The present study aims to explore the effect of perceived stress on depression in a sample of Chinese college students and proposes that both emotion regulation and positive psychological capital play a moderating role between the two, so as to provide rational intervention for the prevention of potential depression among college students. Method In this study, 1,267 college students (46.4% female) from a university in western China were selected for the study using a whole-group convenience sampling method. Results After controlling for gender, this study found that both cognitive reappraisal and positive psychological capital positively moderated the relationship between perceived stress and depression, and both significantly inhibited depression in high and low stress perceivers, and the inhibitory effect was more pronounced in high stress perceivers, but expression inhibition did not moderate the relationship between perceived stress and depression. Discussion The results suggest that college students can be helped to cope with the negative effects of perceived stress on depression by increasing the frequency of their use of cognitive reappraisal strategies and encouraging the accumulation of positive psychological capital. This study provides theoretical and practical implications for rational interventions for depression among college students.
Transient elastohydrodynamic point contact analysis using a new coupled differential deflection method Part 1: Theory and validation

Abstract The paper presents a transient analysis technique for point contact elastohydrodynamic (EHL) lubrication problems using coupled elastic and hydrodynamic equations. Full coupling is made possible by use of a novel differential deflection formulation. The way in which the differential deflection is incorporated into the overall solution method for a point contact is discussed. A range of spatial and temporal discretization methods are incorporated and compared. The method is validated under transient conditions by a detailed comparison with published work produced using a different, independent method incorporating a moving roughness feature. A comparison of the results with different discretization methods leads to the conclusion that spatial central differencing with a Crank-Nicolson temporal discretization is the most effective finite difference scheme, and this is generally equivalent to the finite element discretization given in detail in the paper. A comparison of the results produced for moving rough surfaces suggests that the finite element formulation is preferred.
Role of perigastric arcade removal in serous epithelial ovarian cancers

Introduction Omentectomy is an essential part of cytoreductive surgery (CRS). However, removal of perigastric arcade (PGA) of the omentum is a controversial aspect of omentectomy in view of the fear of injury, vascular compromise and gastroparesis. Hence, we conducted a study to evaluate the necessity and effect of removal of PGA during omentectomy. Methods The nature of the study was a prospective observational study. The study period was for 1 year between 1.3. 2019 and 29.2. 2020. Patients with stage III to IV serous epithelial ovarian cancers – chemo naive/post neoadjuvant chemotherapy, without macroscopic involvement of the PGA were included in the study. Patients were divided into two groups – those who had PGA removed (group 1) and those whose PGA was preserved (group 2). Pre, intra and postoperative factors between the two groups were compared using standard statistical methods. Results Micrometastasis to PGA was present in 36.4% of the patients in group 1. The predictors for this involvement included gross involvement and microscopic involvement of the mobile part of the omentum (p < 0.001), pre surgery Meyer’s score (p < 0.05) and requirement of peritonectomy (p < 0.05) during the CRS implying that higher the peritoneal carcinomatosis, more are the chances of microscopic involvement of PGA. On comparing postoperative outcomes between the two groups, we noted a statistically significant difference in intra-operative time (p < 0.01), prolonged recovery time with increased intensive care unit and hospital stay (p < 0.001) in group 1, although all with small absolute difference. However, there was no significant difference in major post-operative complications or time taken to tolerate soft diet. Conclusion Micrometastasis to PGA was noted in significant number of cases. Its removal is also a safe procedure with minimal morbidity and good postoperative outcomes especially in cases with significant peritoneal carcinomatosis. Hence, it should be considered, provided we are achieving a complete cytoreduction otherwise.
A new look at the north Polar Spur

The North Polar Spur (NPS) seems to consist of distinct shells. On the outside there is the H I shell (the H I NPS) and interior to this is the radio continuum shell (the RC NPS), which contains ionized gas. A region of doffise X-ray enhancement is found inside the RC NPS. From derived values of Faraday depolarization of the radio continuum emission, in conjunction with upper limits on the H.cap alpha. line intensity, we find that in the RC NPS, the parallel component of the magnetic field B(par)> or =1.2 . mu.gauss, and the electron density n(e)< or =0.4 cm/sup -3/. From an attempt to observe Zeeman splitting of the 21 cm line we find that B(par)< or =6 . mu.gauss in the H I NPS. We use these results to present a self-consistent discussion of the region as being the result of a spherical shock which occurred long ago and is no longer expanding.
The Chorioallantoic Membrane Xenograft Assay as a Reliable Model for Investigating the Biology of Breast Cancer

Simple Summary The chorioallantoic membrane (CAM) is a highly vascularized membrane found in avian eggs. Tumor cell lines can be grown on the CAM, which allows for the further analyses of the tumor grafts afterwards. We investigated the biological and growth characteristics of two breast cancer cell lines that resemble two biologically different breast cancer subgroups. Known biological features of the more aggressive breast cancer cell line were clearly confirmed in vitro and in the CAM model. Furthermore, the tissue-based pathological variables assessed in the CAM model were similar to those of the mouse xenografts and human patient tumor tissue. We suggest this in vivo model to be a reliable alternative for breast cancer research to reduce murine animal experiments. Abstract The chorioallantoic membrane (CAM) assay is an alternative in vivo model that allows for minimally invasive research of cancer biology. Using the CAM assay, we investigated phenotypical and functional characteristics (tumor grade, mitosis rate, tumor budding, hormone receptor (HR) and HER2 status, Ki-67 proliferation index) of two breast cancer cell lines, MCF-7 and MDA-MB-231, which resemble the HR+ (luminal) and triple-negative breast cancer (TNBC) subgroups, respectively. Moreover, the CAM results were directly compared with murine MCF-7- and MDA-MB-231-derived xenografts and human patient TNBC tissue. Known phenotypical and biological features of the aggressive triple-negative breast cancer cell line (MDA-MB-231) were confirmed in the CAM assay, and mouse xenografts. Furthermore, the histomorphological and immunohistochemical variables assessed in the CAM model were similar to those in human patient tumor tissue. Given the confirmation of the classical biological and growth properties of breast cancer cell lines in the CAM model, we suggest this in vivo model to be a reliable alternative test system for breast cancer research to reduce murine animal experiments.
A Strong Stability-Preserving Predictor-Corrector Method for the Simulation of Elastic Wave Propagation in Anisotropic Media

In this paper, we propose a strong stability-preserving predictor-corrector (SSPC) method based on an implicit Runge-Kutta method to solve the acoustic- and elastic-wave equations. We first transform the wave equations into a system of ordinary differential equations (ODEs) and apply the local extrapolation method to discretize the spatial high-order derivatives, resulting in a system of semi-discrete ODEs. Then we use the SSPC method based on an implicit Runge-Kutta method to solve the semi-discrete ODEs and introduce a weighting parameter into the SSPC method. On top of such a structure, we develop a robust numerical algorithm to effectively suppress the numerical dispersion, which is usually caused by the discretization of wave equations when coarse grids are used or geological models have large velocity contrasts between adjacent layers. Meanwhile, we investigate the performance of the SSPC method including numerical errors and convergence rate, numerical dispersion, and stability criteria with different choices of the weighting parameter to solve 1-D and 2-D acoustic- and elastic-wave equations. When the SSPC is applied to seismic simulations, the computational efficiency is also investigated by comparing the SSPC, the fourth-order Lax-Wendroff correction (LWC) method, and the staggered-grid (SG) finite difference method. Comparisons of synthetic waveforms computed by the SSPC and analytic solutions for acoustic and elastic models are given to illustrate the accuracy and the validity of the SSPC method. Furthermore, several numerical experiments are conducted for the geological models including a 2-D homogeneous transversely isotropic (TI) medium, a two-layer elastic model, and the 2-D SEG/EAGE salt model. The results show that the SSPC can be used as a practical tool for large-scale seismic simulation because of its effectiveness in suppressing numerical dispersion even in the situations such as coarse grids, strong interfaces, or high frequencies.
Immobilization on Cellulose Paper of a Chemosensor for CdSe-Cys QDs

: The Schiff base ligand H 2 SB derived from the condensation of N -(2-aminobenzyl)-5- (dimethylamino)naphthalene-1-sulfonamide with 4-formyl-3-hydroxybenzoic acid has been investigated as a chemosensor for the detection of CdSe-Cys QDs in water samples. We immobilized H 2 SB onto cellulose paper by forming an amide bond, which results from the condensation of a carboxylic acid and an amine. Three dominant signals located around 270, 330, and 420 nm in the diffuse reﬂectance spectrum of the H 2 SB-modiﬁed paper demonstrated its immobilization. A linear decrease can be observed in the absorbance of the 270 nm band with the increase of the CdSe-Cys QDs concentration from 100 ppb to 2 ppm. The LOD and LOQ show values of 245 and 815 ppb, respectively. An interaction via metal–ligand coordination between CdSe-Cys QDs and H 2 SB has been demonstrated with 1 H NMR, ATR-FTIR, and UV-Vis spectroscopy.
Simulation of solute transport under oscillating groundwater flow in homogeneous aquifers

In this paper, we focus on the influence of temporal variations in the regional hydraulic gradient, particularly, on the impact of temporal variations in the boundary conditions on the spreading of solute plumes in homogenous aquifers. We examined the problem by numerical simulations. Twodimensional fully implicit finite difference model TRANS_GW_2D for the unsteady groundwater flow and a random walk particle tracking model TRANS_RW_2D for solute transport have been developed to solve the governing equations without restriction on the values of aquifer storativity or on the magnitude of the temporal fluctuations. It has been shown that transient flow conditions (in terms of gradient magnitude variability) have a significant impact on contaminant transport only if the amplitude and period of the oscillations are relatively large. For relatively small oscillations, a steady state flow field can be justified. Transient conditions may be relevant in coastal aquifers with high tidal amplitudes. This tidal variation can have an effect on the spreading of solutes and on salt-water intrusion. Our numerical experiments demonstrate that in case of relatively high storativity values, the dispersion coefficient is amplified in time as the plume moves towards the fluctuating boundary.
ELM transport in the JET scrape-off layer

This contribution summarizes a number of aspects of the experimental and modelling programme at JET aimed at improving the characterization and understanding of edge localized mode (ELM) transport in the scrape-off layer (SOL). Divertor target energy deposition asymmetries favouring the inner target for the ion B × ∇B drift directed towards the X-point are observed with infra-red (IR) thermography. Similar trends are seen in the ELM resolved energy radiated in the divertor volume. Particle-in-cell kinetic calculations of the parallel ELM heat transport have been made for a range of ELM energies, revealing the detailed time response of target sheath heat transmission factors and indicating that electrons deposit ∼30% of the ELM energy. The simulation results are in good agreement with experimental measurements of the integral energy deposited at the outer target up to the peak in target heat loads. A transient model of ELM filament energy evolution has been developed at JET and is able to reproduce a number of experimental observations, including the high ion energies observed in the far SOL using an electrostatic retarding field electrostatic analyser (RFA) and estimates of ELM heat fluxes deposited on main chamber limiters. During the ELM, the RFA and a second, SOL turbulence probe, clearly show the presence of coherent spikes in the hot ion flux, the plasma flux and the electron temperature. Field aligned structures have also been seen for the first time on JET in the power deposition on main wall limiters and upper dump plate surfaces using a new wide angle IR camera system. The probe signals are interpreted as the arrival of interspaced plasma filaments, with successive filaments carrying less energy. They are also consistent with the ELM out flux entering the SOL primarily on the outboard side and launching a sound wave disturbance along field lines.