Miracle-dz/UniFAR-FTUs huggingface dataset:
Chemical, physical, microbiological and sensory analyzes of fillets of hybrid sorubins

Sorubim fillets are products with great commercial potential that meet the current preferences for fish consumption. Hybrids of these species have gaining popularity for industrial fish farming. The aim of this work was to characterize fillets obtained from the crosses between Pseudoplatystoma corruscans and Pseudoplatystoma reticulatum (dot and comma hybrid sorubim) and the crosses between Pseudoplatystoma spp. x Leiarius marmoratus (real hybrid sorubim) in terms of physical, chemical, microbiological, and sensory analyzes. The fillets of real hybrid sorubim presented high moisture (77.90%) and protein (17.20%) and low lipid (3.20%) contents compared to the dot and comma hybrid sorubim (75.66, 21.36, and 1.90%, respectively). The variation in the constitution of the real hybrid sorubim had affected other parameters, e.g. it increased the texture evaluated in terms of shear strength (0.58 kgf, against 0.46 kgf for the dot and comma hybrid sorubim fillet), and the reduced sensory acceptation / purchase intention, which are related to the reduced fat content. Purchase intention analysis indicated that the filets of dot and comma hybrid sorubim would be purchased by 95% of the population, while the fillets of the real hybrid sorubim would be purchased for less than 80% of the population.
SPATIO-TEMPORAL DYNAMIC OF LAND DEGRADATION USING REMOTE SENSING-BASED INDEX

Land degradation is the major issue which affect watershed sustainability and following social, economic and environmental of livelihood people. So, early detection of land degradation is necessary for policy-makers to make appropriate decision. In this way, remote sensing method is a candidate choice for assessments and monitoring. In this study, land degradation was assessed using Rain-Use Efficiency (RUE) in the Shazand Watershed, Iran in 1986, 1998, 2008 and 2016. Thus, annual rainfall was calculated using inverse distance weight (IDW), net primary productivity (NPP) were calculated using Landsat images. The results indicated that RUE had increasing and then decreasing trends which were 10.66, 33.77, 20.03 and 9.47 kg C ha-1 yr-1. The results also illustrate that the mean value of RUE in different land uses varied between the irrigated land and orchard that had the highest value and outcrop dominant areas and bareland had the lowest value of RUE among land use categories. It is also established that spatio-temporal analysis of RUE can provide valuable information about the trend of watershed’s sustainability over years.
Land Use Land Cover (LULC) Change Projection in Kathmandu Valley using the CLUE-S Model

In the past few decades the urbanization pattern of the Kathmandu valley has rapidly increased and the process was sensed through the increase in the urban facilities, population growth, and changed LULC pattern. The historical LULC change was analyzed using the generated map and the future scenario was found through the CLUE-S LULC change model and processed in GIS environment. Five scenarios and nine driving forces were considered for the sensitivity and future analysis of the model. Based on the evaluation of the historical maps and the conservation matrix, the built-up area is found to be increased nearby by 5% and the agricultural area decreased by 6.5% during 2010 to 2018. It is concluded that the normal LULC conservation scenario provides more reliable information for the future projection. The simulation result highlights that nearly 4 km2 of fertile and open area will be converted to built-up areas due to the rapid urbanization per decade. This increase in urbanization process leads to more challenges in urban environment management in future.
The SARS CoV-2 spike domain, RGD and integrin binding effect-relationship for vaccine design strategy

Related the need to search new strategy in vaccine design in order to reduce also some rare effect like trombosys for some registered products it is interesting the role played by the SPIKE RGD domain. The binding with molecules like Fibronectin is a process that must to be deeply investigated. A better understanding in this process can be used to improve safety of the new generation of COVID vaccine. The rare effect like thrombosis recognized by regulatory agency produced a modification of technical data sheet of some vaccine so the phenomena Is interesting to be more investigated. Spike protein and its domains are involved in producing pathological effect of the COVID-19 disease. What it is interesting is that some pathological effect of this pathology are similar to some rare side effect produced by some COVID-19 vaccine classes. After a review of interesting literature related this topics is submitted an experimental projects able to verify in vitro the spike procoaugulant property.
ISSN: 2595-573X

Mesenchymal Stem Cells (MSCs) are use used in cell therapy and are isolated from different tissues including skin. Dermal fibroblasts have demonstrated similar potency characteristics to MSCs such expression of surface markers and differentiation towards lineages of mesodermal origin, especially under the influence of epigenetic modulators and growth factors. Cell therapy in veterinary medicine, specifically in cats, represents a challenge owing to the invasiveness of procedures to obtain tissues for MSCs. For this reason, less invasive options are being considered to obtain these cells. The objective of the study was to evaluate the effect of valproic acid VPA (epigenetic modulator), and growth factors (PRP and h-PDGF-B) on expression of surface markers, pluripotency genes and mesodermal differentiation in feline fibroblasts. Skin fibroblasts were isolated from female cats and cultured with VPA and growth factors for 12 days. Cd90, Cd44, ECadherin, Snail, Nanog and Oct4 expression were evaluated at days 5 and 12. Adipogenic, chondrogenic and osteogenic differentiation potential of fibroblasts were evaluated after 12 days of treatment. Cd44 expression increased at day 5 of VPA+PRP treatment (p=0.01). Oct4 and Nanog expression increased at day 5 of VPA + h-PDGF-B treatment (p<0.05). Fibroblasts under treatment with VPA and h-PDGF-B showed the ability to differentiate towards chondrogenesis and osteogenesis. Cell culture protocol for feline fibroblasts with VPA and h-PDGF-B confers plasticity to feline fibroblasts by promoting the expression of Nanog and Oct4 as well as in vitro mesodermal differentiation.
to Those Undergoing Single-Level Surgery at 2 Years Surgery for Lumbar Spinal Stenosis Have Similar Outcomes Patients Undergoing 3-Level-or-Greater Decompression-Only

Background: Stability following multilevel decompressive laminectomy without fusion has been debated using in vitro biomechanical and radiographic models. However, there is a lack of information regarding clinical outcomes for these patients. The aim of the present study was to determine the association between clinical outcomes and number of levels decompressed via laminectomy for treatment of lumbar spinal stenosis. Methods: We performed a retrospective cohort analysis of patients who underwent a primary lumbar laminectomy between 2009 and 2015 by senior orthopedic spine surgeons for lumbar spinal stenosis. Patients were divided into 2 groups based on the number of decompression levels: single level or 3 or more levels. Patient-reported outcomes were obtained in the form of Oswestry Disability Index (ODI) scores, visual analog scale (VAS) scores for the back and leg, 12-Item Short Form Mental and Physical Survey scores, and Veterans Rand 12-Item Health Mental and Physical
A 5 V to 180 V Charge Pump for Capacitive Loads in a 180 nm SOI Process

This paper presents two variants of a high step-up ratio charge pump for high voltage micro electro-mechanical system and condenser microphones. The implementations are based on an additive charge pump topology where respectively 46 and 57 cascaded stages are used to generate an output voltage of 182 V from a supply voltage of 5 V. The two charge pumps have been fabricated in a 180 nm SOI process with a breakdown voltage of more than 200 V and respectively occupy an area of 0.52 mm2 and 0.39 mm2. The charge pumps can output up to 182.5 V and 181.7 V and are designed to drive a capacitive load with a leakage of 2 nA. When driven with a 100 kHz clock, their power consumption is respectively 40 µW and 20 µW. The rise time of the charge pumps output from 0 V to 182 V is less than 5 ms. The implemented charge pumps exhibit state-of-the-art performance for very high voltage dc-dc capacitive drive applications.
Demographics, Clinical profile, Causes and Outcome of Intracerebral Hemorrhage in Neurosurgical Unit in Manipal Teaching Hospital of Western Nepal

Background: This research article aims to evaluate the demographic variables, clinical profile, causes and outcome determinants of spontaneous intracerebral hematoma (SICH) in a population of Western Nepal. The study represents the cases of SICH reported from Manipal Teaching Hospital, a tertiary center at Gandaki province of Western Nepal. Materials and methods: Retrospective data collection and analysis were done with consecutive cases of SICH admitted to our center between January 2018 and March 2019. The variables analyzed include age, gender, chronic conditions like hypertension, diabetes mellitus, history of tobacco abuse, alcohol abuse, Glasgow coma score (GCS) on admission, radiological(CT scan) findings, treatment modality, an outcome at 6 months period, etc. Modified Rankin score (mRS) was used to assess the outcome at discharge and after six months. Results: Our study group of 237 patients included 171 males and 66 females and the mean age of presentation was 64.02 years. The study group included 121 patients (51.1%) who were previously diagnosed with systemic arterial hypertension and 15 patients diagnosed with diabetes mellitus. The most frequent locations of hematoma were basal ganglia (n=127), lobar (n=94), intraventricular hemorrhage (n=69), cerebellar (n=15) and brainstem (n=11). The mean volume of the blood clot on admission was 25.97 ml. surgical evacuation of hematoma and decompression through craniotomy was done in 52 (21.9%) patients. Independent predictors of unfavorable outcomes includes the variables like headache (p=0.007), aphasia (p=0.017), mean GCS score (p=0.00) and motor GCS score (p=0.00); CT finding of intraventricular extension of hemorrhage (p=0.00), midline shift (p=0.00), intracerebral blood volume (p=0.00); and surgery (p=0.007). Conclusion: ICH predominantly affects a younger population in Nepal in comparison to the Western world. The variables include clinical features like headache, aphasia, pupillary size and reaction, mean GCS score and motor GCS score; CT finding of intraventricular extension of hemorrhage, midline shift, intracerebral blood volume; and surgery were the predictors of an unfavorable outcome. On binary logistic regression, the ICH score was the most consistent predictor of unfavorable outcomes in terms of MRS (OR 2.236, p=0.002).
Psychological factors associated with adolescent sexual behavior

Sexually transmitted infections are increasing in Brazilian adolescents and youth. The aim of this study was to investigate the association of self-esteem, self-efficacy, and other psychosocial variables with condom use behavior and sexual debut in a sample of adolescents from Santa Maria-RS. Data was collected with 452 adolescents (57% girls), mean age of 15.9 years (SD = 1.4), using the Brazilian Youth Questionnaire – Phase II. Condom use behavior was not associated with self-esteem or self-efficacy in the logistic regression model, contrary to the main hypothesis. General self-efficacy was positively associated with sexual debut, while religiosity was negatively associated with this outcome. Family support was associated with older age at sexual debut. The findings support the importance of analyzing different sexual behaviors separately, as they may have distinct predictors. Studies should use specific measures of self-efficacy when studying sexual behavior and measure how participants value different sexual behaviors.
Tomato Role on Seven Deadliest Non-Communicable Disease

Non-communicable diseases such as ischemic heart disease, stroke, chronic obstructive pulmonary disease, lung cancer, Alzheimer, diabetes melitus, and kidney disease are leading causes of death in the world. There are many risk factors which can contribute to non communicable diseases such as dietary. Vegetable consumption such as tomato may lower risk factors to non-communicable diseases because of its active ingredient, lycopene, retinol, alpha tomatine, and tomatidine. In this review, authors aim to explain the mechanism of tomato’s active compound in lowering risk factors of non-communicable disease based on biomarker found on each disease collected from articles and journals. Lycopene and retinol have proven in reducing ischemic heart disease and stroke because of its antiatherogenic properties and anti-inflammatory effect. Antioxidative and anti-inflammatory effect of lycopene also proven in lowering risk factors of chronic obstructive pulmonary diseases by modulate reverse cholesterol transport, so cholesterol homeostasis is created. In lung cancer, lycopene and other bioactive compound such as α-tomatine and tomatidine also have an anti-proliferative effect by interacting with Epidermal growth factor receptor (EGFR). Its ability to reduce the final product of lipid peroxidation level makes lycopene lower Alzheimer risk factor. There is much more function of tomato’s active coumpound although pure tomato has contradictive effect on some disease.
Deterrence of Intelligent DDoS via Multi-Hop Traffic Divergence

We devise a simple, provably effective, and readily usable deterrence against intelligent, unknown DDoS threats: Demotivate adversaries to launch attacks via multi-hop traffic divergence. This new strategy is motivated by the fact that existing defenses almost always lag behind numerous emerging DDoS threats and evolving intelligent attack strategies. The root cause is if adversaries are smart and adaptive, no single-hop defenses (including optimal ones) can perfectly differentiate unknown DDoS and legitimate traffic. Instead, we formulate intelligent DDoS as a game between attackers and defenders, and prove how multi-hop traffic divergence helps bypass this dilemma by reversing the asymmetry between attackers and defenders. This insight results in EID, an Economical Intelligent DDoS Demotivation protocol. EID combines local weak (yet divergent) filters to provably null attack gains without knowing exploited vulnerabilities or attack strategies. It incentivizes multi-hop defenders to cooperate with boosted local service availability. EID is resilient to traffic dynamics and manipulations. It is readily deployable with random-drop filters in real networks today. Our experiments over a 49.8 TB dataset from a department at the Tsinghua campus network validate EID's viability against rational and irrational DDoS with negligible costs.
Two types of inspiratory muscle training on muscle strength in patients submitted to coronary artery bypass grafting: clinical trial

Introduction: Coronary artery bypass grafting (CABG) causes changes in the respiratory musculature that affects functional capacity and postoperative complications (POC). Inspiratory muscle training (IMT) is a tool used for these patients, but it is not known what the best form is to increase strength. Objective: To investigate whether IMT with a linear pressure load device is superior to the inspiratory incentive on functional capacity and muscle strength of patients undergoing CABG. Methods: This is a clinical trial. Patients were assessed preoperatively for inspiratory muscle pressure (MIP), expiratory pressure (MEP), peak expiratory flow (PEF), six-minute walk test (6MWT) and functional independence measure (FIM). After surgery, they were divided into three groups: control group (CG), training group with linear pressure load (IMT) and inspiratory incentive group (IG). On the day of discharge, all patients had their previous variables reassessed. Results: The study included 56 patients, 31 (55.4%) were male and an average age of 55 ± 12 years. There was a significant reduction in all variables, in relation to MIP, the IMT showed a higher value in the postoperative period 83 ± 19 cmH2O, against 70 ± 15 cmH2O in the CG and 80 ± 15 cmH2O in the IG (p < 0.001). The same behavior was observed in MEP, 77 ± 12 cm H2O in IMT, 67 ± 14 cmH2O in CG and 75 ± 10 cmH2O in IG (p < 0.001). Regarding the 6 MWT, there was a lesser loss in the IMT from 434 ± 15 m to 398 ± 20 m in IG (p < 0.001). Conclusion: It is concluded that muscle training with a linear pressure load device is superior to training with incentive on functional capacity and muscle strength in patients undergoing CABG.
Graphene-based surface heater for de-icing applications

Graphene-based de-icing composites are of great interest due to incredible thermal, electrical and mechanical properties of graphene. Moreover, current technologies possess a number of challenges such as expensive, high power consumption, limited life time and adding extra weight to the composites. Here, we report a scalable process of making highly conductive graphene-based glass fibre rovings for de-icing applications. We also use a scalable process of making graphene-based conductive ink by microfluidic exfoliation technique. The glass fibre roving is then coated with graphene-based conductive inks using a dip-dry-cure technique which could potentially be scaled up into an industrial manufacturing unit. The graphene-coated glass roving demonstrates lower electrical resistances (∼1.7 Ω cm−1) and can heat up rapidly to a required temperature. We integrate these graphene-coated glass rovings into a vacuum-infused epoxy–glass fabric composite and also demonstrate the potential use of as prepared graphene-based composites for de-icing applications.
Recent Trends in Answer Script Evaluation – A Literature Survey

Assessment of answer scripts is an integral part of an examination and education system. A fair, consistent, unbiased, and correct valuation ensures the integrity of an examination system and is important for all education institutions. Since manual valuation is cumbersome and can be biased or influenced by the perception/mood of the evaluator, automatic grading of scripts has become very relevant. Automatic short answer grading (ASAG) techniques have been widely researched in the last decade and have assumed increased relevance because of online teaching and examinations during the Covid-19 pandemic. This review paper focuses on the recent works in the area of automatic answer grading and compares the techniques, methodologies employed, and the consequent results to evaluate their effectiveness. It discusses the advantages and limitations of the techniques by systematically categorizing the questions into both long/short as well as open-ended/close-ended questions and suggests a new model for improving the grading outcomes.
Food Consumption as a Risk Factor of Anemia among Indonesian Pregnant Women: A Cross-sectional Study among Javanese Ethnic Group

BACKGROUND: Anemia during pregnancy causes several adverse effects. Furthermore, in Indonesia, this leads to restrictions among pregnant women. The information on this situation is still limited, and more research needs to be conducted. AIM: Therefore, this study aims to investigate the association between food consumption and anemia among pregnant women. METHODS: This is a cross-sectional descriptive research that involved 424 pregnant women. Furthermore, written informed consent was obtained from respondents before data collection. A self-administered questionnaire was used to assess the food consumption and demographic data. Hemoglobin concentration was further measured using a haemoglobinometer, and data were analyzed using a descriptive statistical Chi-square, and a Multiple Logistic Regression test. RESULTS: It was found that half of the respondents suffered from anemia (46.5%). Furthermore, the Multiple Logistic Regression test showed that tea, liver, eggs, and iron consumption with values of (odds ratio [OR] = 5.075, p < 0.001), (OR = 4.128, p < 0.001), (OR = 3.590, p < 0.01), and (OR = 3.837, p < 0.05), respectively, had significant correlations with anemia among pregnant women. CONCLUSIONS: Anemia is commonly experienced by Indonesian pregnant women. Therefore, health-care providers should focus on preventing anemia in pregnant women by reducing their tea intake and increasing the consumption of iron-rich foods or supplements.
Radiographic Assessment of the Proximal Femoral Anatomy in An Indigenous African Adult Population

Background: Hip surgeries such as fracture fixation, corrective osteotomy, hemiarthroplasty, or total hip arthroplasty require accurate preoperative templating for a successful outcome. Such templating is done using the proximal femur and the acetabulum radiographs, depending on the planned surgery. Understanding the normal radiographic anatomy of the proximal femur is crucial to differentiate a normal from pathological anatomy. Proximal femoral anatomic indices include the femoral head diameter, femoral neck diameter, femoral neck length, femoral offset, femoral neck axis length and the femoral neck-shaft angle. Aim: This study assesses and establishes the average values of the proximal femoral anatomy in an indigenous African adult population. Method: This cross-sectional study examined 190 normal anteroposterior (AP) radiographs of the pelvis. The mean age, weight and height of the subjects were obtained. The following proximal femoral anatomic parameters were measured: femoral neck length (FNL), femoral neck diameter (FND), femoral head diameter (FHD), femoral neck-shaft angle (FNSA), femoral offset (FO) and femoral neck axis length (FNAL). The authors compared the mean difference of the parameters between the genders and the age categories and assessed the parameter correlations with the patients’ weight and height. Results: Males constituted 63 (33.2%) of the study population. The mean age of the subjects was 51.46 years (SD = 16.37). The mean weight was 76.13 kg, while the mean height was 1.62 m. The mean values of the proximal femoral parameters were as follows: FNL 4.52cm, FND 3.42cm, FHD 4.76cm, FNSA 132.960, FO 4.09cm, and FNAL 10.34cm. Males have a significantly higher mean value in all the parameters except the FO. None of the parameters showed any significant difference among the age categories except the FNL. A post-hoc analysis showed that the difference in the FNL lies between the young and the elderly age groups. The subjects’ height correlated with all the parameters except FNSA, while the weight correlated with the FND, FNSA and FNAL. Conclusion: The proximal femoral anatomy in Africans differed from those published in foreign literature. This knowledge is crucial for implant manufacturing companies and preoperative templating for hip surgeries. KEY WORDS: Proximal femur, Anatomy, Black population.