Miracle-dz/UniFAR-FTUs huggingface dataset:
CXCL10 haplotypes and multiple sclerosis: association and correlation with clinical course

CXCL10 (interferon‐γ‐inducible protein‐10) levels are increased in cerebrospinal fluid of multiple sclerosis (MS) patients with symptomatic attacks of inflammatory demyelination, supporting a role for this molecule in MS pathogenesis. Two hundred and twenty‐six patients with MS and 235 controls were genotyped for G → C and T → C single nucleotide polymorphisms (SNPs) in exon 4 of CXCL10 gene. Haplotypes were tested for association and correlated with clinical variables. The two SNPs studied were in complete linkage disequilibrium. None of the determined haplotypes was associated with MS. However, carriers of the GGTT haplotype (defined as wild type, according to the sequence in National Centre for Biotechnology Information (NCBI) database) had a significantly lower progression index than non‐carriers (P = 0.016). Furthermore, amongst patients who had an initial relapsing remitting (RR) course of the disease, the time between onset and second episode was significantly longer in GGTT carriers (P = 0.021). Considering secondary progressive (SP)–MS patients, the time between the initial RR form and the subsequent worsening to SP was longer in this group (P = 0.08). Therefore, the GGTT haplotype of the CXCL10 gene is not a susceptibility factor for the development of MS, but is probably to influence the course of MS, possibly contributing to slow down the progression of the disease.
Laser Processing of Refractory Metal - Refractory Carbide Alloys

The objective of the present study was to laser process a refractory metal – refractory carbide alloy based on W-Ti-C ternary system for severe service applications. The key concept was to cast a eutectic alloy of tungsten and titanium carbide/carbonitride straight from the melt through laser materials processing route. In the present study, a WTi-C ternary alloy has been laser processed into three-dimensional objects and surface protective coatings. Two novel fabrication systems were designed to build threedimensional objects, namely tower nozzle solid freeform fabrication system and axissymmetric laser powder deposition system. W-Ti-C alloy based protective coatings were deposited on graphite substrates, through laser melting of pre-placed powder mixture, to widen the use of carbon structural elements for high temperature applications. A method for depositing W-Ti-C alloy on steel using multi-intermediate layers strategy is discussed and the preliminary results are presented in this study.
Power supply noise aware floorplanning and decoupling capacitance placement

Power supply noise is a strong function of the switching activities of the circuit modules. Peak power supply noise can be significantly reduced by judiciously arranging the modules based on their spatial correlations in the floorplan. In this paper, power supply noise is, for the first time, incorporated into the cost function to determine the optimal floorplan in terms of area, wire length, and power supply noise. Compared to conventional floorplanning, which only considers area and wire length, power supply noise aware floorplanning can generate better floorplan both in terms of area and peak noise. The decoupling capacitance required by each module is also calculated and placed in the vicinity of the target module during the floorplanning process. Experimental results on MCNC benchmark circuits show that the peak power supply noise can be reduced by as much as 40% and both the total area and wire length are improved due to the reduced total decoupling capacitance budget gained from reduced power supply noise.
Intracolonic pressure measurements during hydrostatic and air contrast barium enema studies in children.

PURPOSE To prospectively evaluate intraluminal pressure changes in the colon of children undergoing conventional hydrostatic (barium and water-soluble contrast material) and air contrast barium enema studies. MATERIALS AND METHODS Dynamic intracolonic pressure was measured in 26 children undergoing hydrostatic barium (23% wt/vol) enema studies, air contrast barium enema studies, or water-soluble contrast material enema examinations. Measurements were obtained with a measuring device capable of recording rapid changes in pressure. Pressure measurements were obtained with the contrast reservoir system open (contrast material was free to run through the tubing into the patient's colon) and closed (tube was clamped). RESULTS The colonic pressures during the filling phase with liquid contrast material were equal to those elsewhere at the same level with the hydrostatic system. Mean pressure ranged from 30 to 50 mm Hg with peaks of more than 100 mm Hg during Valsalva maneuvers. During air contrast barium enema studies, sharp pressure increases and rapid swings in the intracolonic pressure occurred during and after manual insufflation of air. CONCLUSION During conventional hydrostatic barium enema studies, intracolonic pressures remain low. During air insufflation, there were intermittent high, sharp pressure peaks.
Novel temporal configurations of stimuli produce discrete changes in immediate‐early gene expression in the rat hippocampus

Changes in limbic brain activity in response to novel configurations of visual stimuli were assessed by quantifying two immediate‐early genes, c‐fos and zif268. Rats were first trained to use distal, visual cues to support radial‐arm maze performance. Two separate sets of visual cues were used, one in the morning (Set A) and the other in the afternoon (Set B). On the final day the experimental group was tested with a novel configuration created by combining four of the eight visual cues from Set A with four of the eight visual cues from Set B. Although each individual cue was in a familiar location, the combination of cues was novel. Comparisons with a control group revealed discrete decreases in Fos centred in the hippocampus and retrosplenial cortex. The hippocampal c‐fos findings produced a dissociation with the perirhinal cortex, where no change was observed. Other regions seemingly unaffected by the novel stimulus configuration included the postrhinal, entorhinal and parietal cortices. Zif268 levels in the experimental group increased in the anterior ventral thalamic nucleus. Although previous studies have shown how the rat hippocampus is involved in responding to the spatial rearrangement of visual stimuli, the present study examined temporal rearrangement. The selective immediate‐early gene changes in the hippocampus and two closely related sites (retrosplenial cortex and anterior ventral thalamic nucleus) when processing the new stimulus configuration support the notion that the hippocampus is important for learning the ‘relational’ or ‘structural’ features of arrays of elements, be they spatial or temporal.
QUANTITATIVE GENETICS OF PLASTRON SHAPE IN SLIDER TURTLES (TRACHEMYS SCRIPTA)

Abstract Shape variation is widespread in nature and embodies both a response to and a source for evolution and natural selection. To detect patterns of shape evolution, one must assess the quantitative genetic underpinnings of shape variation as well as the selective environment that the organisms have experienced. Here we used geometric morphometrics to assess variation in plastron shell shape in 1314 neonatal slider turtles (Trachemys scripta) from 162 clutches of laboratory-incubated eggs from two nesting areas. Multivariate analysis of variance indicated that nesting area has a limited role in describing plastron shape variation among clutches, whereas differences between individual clutches were highly significant, suggesting a prominent clutch effect. The covariation between plastron shape and several possible maternal effect variables (yolk hormone levels and egg dimensions) was assessed for a subset of clutches and found to be negligible. We subsequently employed several recently proposed methods for estimating heritability from shape variables, and generalized a univariate approach to accommodate unequal sample sizes. Univariate estimates of shape heritability based on Procrustes distances yielded large values for both nesting populations (h2 ≈ 0.86), and multivariate estimates of maximal additive heritability were also large for both nesting populations (hmax2 ≈ 0.57). We also estimated the dominant trend in heritable shape change for each nesting population and found that the direction of shape evolution was not the same for the two sites. Therefore, although the magnitude of shape evolution was similar between nesting populations, the manner in which plastron shape is evolving is not. We conclude that the univariate approach for assessing quantitative genetic parameters from geometric morphometric data has limited utility, because it is unable to accurately describe how shape is evolving.
Biochemical parameters as monitoring markers of the inflammatory reaction by patients with chronic obstructive pulmonary disease (COPD)

Background Chronic obstructive pulmonary disease (COPD) is an airway inflammatory disease caused by inhalation of toxic particles, mainly cigarette smoking, and now is accepted as a disease associated with systemic characteristics. Objective The aim of this work was to investigate and compare selected biochemical parameters in patients with and without COPD. Material and Methods Observation group consisted of clinically stable patients with COPD (n = 60). The control group was healthy persons from the general population, without COPD, who were divided into two subgroups – smokers (n = 30) and non-smokers (n = 30). Laboratory parameters were investigated by automated clinical chemistry analyzer LISA 200th. Results Albumin in our measurements showed an average value of 39.55 g.l-1 in the patient population; 38.89 g.l-1 in smokers and in non-smokers group 44.65 g.l-1. The average value of pre-albumin in the group of patients was 0.28 ± 0.28 g.l-1 and 0.30 ± 0.04 g.l-1 in smokers group. The average value of the orosomucoid in patients was about 1.11 ± 0.90 mg.ml-1. In the group of smokers, the mean value of orosomucoid was 0.60 ± 0.13 mg.ml-1. The level of C-reactive protein (CRP) in the patient group reached an average value of 15.31 ± 22.04 mg.l-1, in the group of smokers was 5.18 ± 4.58 mg. l-1. Prognostic inflammatory and nutritional index (PINI) in the group of patients showed a mean value of 4.65 ± 10.77 and 0.026 ± 0.025 in smokers. Conclusions The results of this work show, that the values of index PINI in COPD patients are significantly higher than in smokers (P <0.001). This along with other monitored parameters indicative inflammation as well as a catabolic process that occurs in the organism of patients with COPD.
CSE 255-A Assignment 2 Report

In this assignment, we use Amazon movie reviews data to predict the rating of a given movie. Here we mainly use two models to build the predictor – linear regression and latent factor. When choosing the features of the linear regression, we use natural language processing techniques to analyze the reviews text to get whether the reviews is positive or negative. When applying the latent factor model, we try to figure out the rating baseline over all the movies and the rating offset for every specific user and movie. 1. EXPLANATORY ANALYSIS In assignment 2, we use Amazon movie reviews from http: //snap.stanford. edu/data/web-Movies.html. This dataset consists 7,911,684 movie reviews from Amazon. The reviews span a period of 15 years, from Aug 1997 to October 2012. The total number of movies covered by this dataset is 16,341. The total number of users covered by this dataset is 889,176, and 16,341 of these users had writen more than 50 reviews. The dataset is organized in the following format. " prod-uct/productId " indicates the Id of a movie on Amazon. " re-view/userId " indicates the Id of a user on Amazon. " re-view/profileName " indicates the user name of the writer of the review. " review/helpfulness " indicates how many users have rated this review and how many users considered this review was helpful to them. " review/score: 5.0 " indicates the rating given by the user to this movie, which is also what we want to predict. " review/time " shows when the review was written in unix time. " review/summary " and " review/text " gives us the summary and content of the review. Our task is to predict rating based on user, item, and Permission to make digital or hard copies of all or part of this work for personal or classroom use is granted without fee provided that copies are not made or distributed for profit or commercial advantage and that copies bear this notice and the full citation on the first page. Copyrights for components of this work owned by others than ACM must be honored. Abstracting with credit is permitted. To copy otherwise, or re-publish, to post on servers or to redistribute to lists, requires prior specific permission and/or a fee. Request permissions from permissions@acm.org. review text. We will use MSE to indicate the performance of our model. The baseline we compared to our model is to …
Leachate Chemistry of Mixtures of Fly Ash and Alkaline Coal Refuse

In the past, acid mine drainage (AMD) associated with coal mining operations and the disposal of coal refuse have been a driving force behind research efforts on the properties of coal combustion products (CCPs) [1]. The results from research over the last 15 years clearly indicate that bulk-blended CCP has the potential to ameliorate AMD production in coal refuse as long as acid-base balance concerns are met [1,2].
Using remote sensing to assess the impact of beaver damming on riparian evapotranspiration in an arid landscape

Beaver damming creates and maintains riparian ecosystems in arid regions, which are often afflicted by seasonal and multi‐year droughts. We hypothesize that beaver ponds act as buffers against the effects of drought on nearby riparian vegetation via the following mechanism: Beaver ponds formed upstream of each dam retain water during wetter parts of the year, then during drier parts of the year, they gradually release that water into nearby soil where it is accessible to the roots of riparian vegetation. We calculated the evapotranspiration (ET) and normalized difference vegetation index (NDVI) of riparian vegetation on Susie and Maggie Creeks in north‐eastern Nevada from 2013 to 2016 and then compared the ET and NDVI to the location and intensity of beaver damming on the creeks. We found that the ET of riparian areas with beaver damming was 50–150% higher than the ET in riparian areas without beaver damming and that NDVI in dammed riparian areas was 6–88% higher than that in undammed areas. These differences peaked in mid‐summer when the landscape is at its hottest and driest state. There was no apparent loss of beaver pond drought buffering as a multi‐year drought (2013–2015) progressed. Our results indicate that riparian areas with beaver damming in arid landscapes are better able to maintain vegetation productivity than areas without beaver damming during both short and extended periods of drought.
Human Motion Analysis with the Help of Video Surveillance: A Review

Recent research in computer has persuaded more studies in human motion observation as well as analysis. Visual analysis of human motion is more active component in computer vision. With the help of video surveillance we are able to work in this area conveniently. Human motion analysis concerns the detection, tracking, recognition of human activities and also human behaviours. This paper helps to comprehend multiple techniques of human motion detection and behaviour understanding.
Shear Strengthening of RC T Beam using CFRP Laminate: A Review

This paper presents the Literature Review of carbon fiber reinforced polymer (CFRP) strips to reinforced concrete (RC) as a strengthening solution for T-beams. Although a great deal of research has been carried out on Rectangular beams strengthened with Fibre-Reinforced Polymer composites (FRP), Fiber reinforced polymer (FRP) composites have been increasingly studied for their application in the flexural or shear strengthening of reinforced concrete (RC) members. A detailed discussion of the shearstrengthening repair with FRP is undertaken. This paper will be limited to research of CFRP material externally bonded to the tensile face of concrete beams. In particular, research studying the effect of externally applied CFRP materials on the shear performance of reinforced concrete beams will be reported. Keywords—CFRP, Concrete, Flexural, FRP, Shear, Strengthening.
Battery management for grid-connected PV systems with a battery

Photovoltaic (PV) power generation systems are one of the most promising renewable power sources to reduce carbon footprint. Grid-connected PV power systems do not generally have a battery to store the excess charge. However, due to severe imbalance between the peak PV power generation and peak load demand, battery-less Grid-connected PV systems are much less effective for the purpose of power generation and demand mismatch mitigation. Grid-connected PV systems equipped with a battery indeed require elaborate management. This is the first paper that introduces a systematic battery management optimization that accommodates arbitrary electricity billing policies. We formulate an optimization framework to determine the battery charging current from the Grid and PV array taking into account the limited battery capacity, power converter efficiency, battery's internal resistance and rate capacity effect, and maximum power tracking of the PV array. Experimental results show that the proposed algorithm effectively reduces the electricity bill by as much as 28% when compared with previous state-of-the-art battery management policies.
Differential Loss and Retention of Cytoglobin, Myoglobin, and Globin-E during the Radiation of Vertebrates

If rates of postduplication gene retention are positively correlated with levels of functional constraint, then gene duplicates that have been retained in a restricted number of taxonomic lineages would be expected to exhibit relatively low levels of sequence conservation. Paradoxical patterns are presented by gene duplicates that have been retained in a small number of taxa but which are nonetheless subject to strong purifying selection relative to paralogous members of the same multigene family. This pattern suggests that such genes may have been co-opted for novel, lineage-specific functions. One possible example involves the enigmatic globin-E gene (GbE), which appears to be exclusively restricted to birds. Available data indicate that this gene is expressed exclusively in the avian eye, but its physiological function remains a mystery. In contrast to the highly restricted phyletic distribution of GbE, the overwhelming majority of jawed vertebrates (gnathostomes) possess copies of the related cytoglobin (Cygb) and myoglobin (Mb) genes. The purpose of the present study was 1) to assess the phyletic distribution of the Cygb, Mb, and GbE genes among vertebrates, 2) to elucidate the duplicative origins and evolutionary histories of these three genes, and 3) to evaluate the relative levels of functional constraint of these genes based on comparative sequence analysis. To accomplish these objectives, we conducted a combined phylogenetic and comparative genomic analysis involving taxa that represent each of the major lineages of gnathostome vertebrates. Results of synteny comparisons and phylogenetic topology tests revealed that GbE is clearly not the product of a recent, bird-specific duplication event. Instead, GbE originated via duplication of a proto-Mb gene in the stem lineage of gnathostomes. Unlike the Mb gene, which has been retained in all major gnathostome lineages other than amphibians, the GbE gene has been retained only in the lineage leading to modern birds and has been independently lost in at least four major lineages: teleost fish, amphibians, mammals, and nonavian reptiles. Despite the restricted phyletic distribution of this gene, our results indicate that GbE is one of the most highly conserved globins in the avian genome.
Computerization of the workplace: testing attitudinal effects with a causal model

This paper examines various aspects of computerization and their effects upon quality of work life in organizations. An integrative model was developed which views quality of work life as an ever changing dimension influenced not only by computerization, but, also, by perception of career success as well as non-work factors. Evaluation of gathered data supported the model in that workers experiencing computerization positively were more likely to exhibit organizational commitment. Furthermore, computerization and perception of career success had an impact upon the individual's role ambiguity and role conflict in the workplace. Supportive and unsupportive findings are discussed, with future directions for organizational research outlined. Implications for practitioners are pointed out as well.
Predicting User Influence in Social Media

Understanding influence plays a vital role in enhancing businesses operation and improving effect of information propagation. Therefore the user influence in social media, such as Twitter, is widely studied based on different standards, such as the number of followers, retweets and so on. However, little work considers the accurate click number of short URLs as the measurement of influence. In Twitter short URLs are frequently included in tweets because of the limitation of characters. And some users may focus more on click number of the URLs instead of the number of followers or retweets. Thus, it is necessary to analyze the factors that impact the click number received by URLs of users. In this paper, we conduct the predictive analyses about the user influence which is measured by the click number of short URLs. We first exploit a wide range of possible features consisting of the sets of user properties, behavior and topics. And then we employ the logistic regression analysis to identify the significant features for predicting the user influence, and find most of features we proposed have a significant predictive power to the user influence. Finally based on the large scale Twitter data, four models are used for the prediction and the Bagging model achieves the best result, an overall accuracy of more than 82%.
Tailored Summary for automatic poster generator

Information delivery with posters is more effective than textual because of human cognitive abilities to understand information is increasing with the help of the graphical representation of the visual system. However, for some people, making posters is more difficult than making paper because it requires the ability to deliver information visually and the ability to extract critical information. But with the development of methods of extracting information in a text, appears an opportunity to generate poster automatically. This paper's aim is to develop an automated generation of poster by implementing paper summarization methods Tailored Summary that extracts information on paper using the rhetorical classification results of sentences. This method allows the generation of a poster performed using the method of summarizing a paper by considering the information needs of the user. The classification model has a F-Measure value of 0.804 and average users score of the posters generated gained is 6.622. Maximal Marginal Relevance is used in the process of sentences selection.