Miracle-dz/UniFAR-FTUs huggingface dataset:
Tumor necrosis factor and interleukin ICU increase vascular endothelial permeability

ROYALL, JAMES A. , ROGER L. BERKOW, JOSEPH S. BECKMAN, M. KATHY CUNNINGHAM, SADIS MATALON, AND BRUCE A. FREEMAN. Tumor necrosis factor and interleukin ICY increase vascular endothezial permeability. Am. J. Physiol. 257 (Lung Cell. Mol. Physiol. 1): L399-L410, 1989. -Endotoxic shock is associated with acute vascular endothelial injury resulting in edema. Tumor necrosis factor (TNF) and interleukin 1 (IL-l) are cytokines produced by endotoxin-stimulated mononuclear phagocytes that are potential mediators of endotoxic shock. In this study, we investigated the effects of TNF and IL-la on vascular endothelial cell permeability in vitro. The movement of radiolabeled macromolecules of different sizes (57Co-vitamin B12, 1251-cytochrome c, and 1311-albumin; 6.535A) across bovine aortic endothelial cell monolayers was measured after exposure to these cytokines. TNF induced a timeand dose-dependent increase in endothelial cell monolayer permeability that was enhanced in the presence of serum. The peak increase was noted after 12 h of incubation with less alteration of permeability with longer incubations. IL-la! caused a similar timedependent increase in endothelial cell monolayer permeability, but the peak effect of IL-la was seen after 24 h. Therefore the increased permeability seen with TNF cannot be explained by release of endogenous IL-l alone. Neither TNF nor IL-la increased release of [14C]adenine, and the only effect on lactate dehydrogenase release was a small, but statistically significant, increase after 24 h of incubation. From these studies, we conclude that TNF and IL-la directly increase vascular endothelial cell permeability in vitro and speculate that these cytokines may be involved in the acute vascular endothelial injury associated with endotoxic shock.
Antecedents of faith integration self-efficacy in PreK-12 Mennonite schools in North America

ABSTRACT Private Christian schools in North America endeavour to provide an educational experience that integrates religious and academic training for their preK-12 students. The integration of faith and academics has been studied in higher education institutions in North America, but not substantially in preK-12 schools. This study uses the lens of teacher self-efficacy to examine Christian school teachers’ confidence to integrate faith into their instructional practices. A survey was conducted that drew responses from 390 educators from 18 Mennonite-affiliated schools across North America. Responses indicated generally high levels of faith integration self-efficacy for all teachers; however, teachers felt least confident in drawing parents into the process. Regression analysis showed that individual factors did predict faith integration self-efficacy. Implications of these findings are discussed.
Correlation of ultrasonography and fine needle aspiration cytology for diagnosis of malignancy in thyroid lesions: a study of 100 cases

<p class="abstract"><strong>Background:</strong> The majority (90%) of thyroid lesions are benign as malignancy occurs only 1 in 10 thyroid nodules. The purpose of ultrasonography (USG) and fine needle aspiration cytology (FNAC) is to pick the patients having malignancy for surgical intervention. The objective of present study is to correlate ultrasonography findings with FNAC for diagnosis of malignancy in thyroid lesions by relating these findings to histopathological examination (HPE) reports. </p><p class="abstract"><strong>Methods:</strong> A prospective clinical study carried out from September 2019 to February 2021, in the Department of Ear Nose and Throat (ENT), Mamata Medical College, Khammam, in patients with clinical evidence of thyroid swelling. Ultrasound and FNAC were done in all cases and HPE were done in cases where surgeries were performed at our institution. The results were analysed. </p><p class="abstract"><strong>Results:</strong> According to USG,<strong> </strong>out of 100 cases 93 cases were found to be of benign thyroid swellings, 4 cases were suspected malignant and 3 cases were found malignant. According to FNAC, out of 100 cases 97 cases were benign and 3 cases were confirmed to be malignant. Two cases which were found to be malignant on both USG and FNAC were confirmed as malignant according to HPE report. </p><p class="abstract"><strong>Conclusions:</strong> USG is a sensitive modality in the assessment of thyroid swellings with good accuracy. FNAC also provides the most direct and specific information about thyroid lesions. It is suggested that USG followed by FNAC provides better diagnosis in thyroid lesions. </p>
INVESTIGATION OF THE EFFECT OF SERVICE QUALITY (SQ) ON PATIENT SATISFACTION (PS) IN GHANA USING THE SERVQUAL MODEL: THE CASE OF GREATER ACCRA REGIONAL HOSPITAL (GARH)

The study’s purpose was to investigate the role service quality (SQ) play in achieving patient satisfaction (PS), examine the nature of hospital staff/patience relationship and to explore the challenges faced by healthcare workers in Greater Accra Regional Hospital [GARH], a prime provider of secondary public healthcare in Ghana. The study was based on questionnaires/in-depth interviews completed by 200 respondents selected via convenient sampling. A modified version of the "SERVQUAL” model was used for measuring SQ and consequently PS. Data analysis included descriptive statistics, principal component analyses, exploratory factor analyses with varimax rotation, reliability/validity analyses, and multiple regression analyses. Data elaboration and processing identify main factors affecting the patients’ overall preferences where the findings in particular reveal positive results towards SQ and PS. In this circumstance, findings/recommendations established, should be considered crucial for hospital administrators/policy makers when dealing with decisions affecting SQ assessment. karşılaştığı ikincil ana sağlayıcısı. uygun örnekleme yoluyla seçilen 200 katılımcı / "SERVQUAL" modelinin versiyonu, SQ ve dolayısıyla ölçmek kullanıldı. Veri analizi, istatistikleri, bileşen analizlerini, varimax rotasyonlu keşif faktör analizlerini, güvenilirlik / geçerlilik analizlerini ve çoklu regresyon analizlerini içeriyordu. Veri ayrıntılandırma ve işleme Özellikle bulguların SQ ve PS'ye yönelik olumlu sonuçlar ortaya çıkardığı durumlarda hastaların genel tercihlerini etkileyen ana faktörler Bu durumda, oluşturulan bulgular / öneriler, SQ değerlendirmesini etkileyen kararlarla uğraşırken hastane yöneticileri / politika yapıcılar için çok önemli kabul edilmelidir.
How macroeconomic indicators influence gold price management

PurposeThis study purposes to measure the influencing relations between macroeconomic indicators and the prices of gold. Further study measures several factors with the gold price in the context of the United States.Design/methodology/approachThe secondary data are collected to measure relationship and fluctuation of gold prices the data collected from the website world development indicators (WDI) for the period of 31 years 1990–2019. This paper uses different econometric analysis such as analytical unit root test for stationary of data, descriptive statistical analysis for description of data, correlation coefficient test for measuring the inter correlation, and ordinary least square regression analysis for determine the impact of dependent and independents variables. In this research paper, gross domestic product (GDP), inflation rate (IR), unemployment rate (UR), real interest rate (RIR), gross national product (GNP), standard trade value (STV) are included in macroeconomic indicators and consider as independent. The gold prices are considered as dependent variable.FindingsThis study's overall results show an important and optimistic association between GDP, IR and STV with the gold price. Moreover, the RIR shows negative and does not show significant relation with the gold prices.Originality/valueSince several economic crises were included during the data selection studied in this research paper, data error may be present, resulting in the instability of the overall data. However, the study still hopes to find the guiding role of these macro gold price factors in the price of gold from the limited data set. The basic scope of research is that research is limited in the United States.
Social Behavior, Ovary Size, and Population of Origin Influence Cuticular Hydrocarbons in the Orchid Bee Euglossa dilemma

Cuticular hydrocarbons (CHCs) are waxy compounds on the surface of insects that prevent desiccation and frequently serve as chemical signals mediating social and mating behaviors. Although their function in eusocial species has been heavily investigated, little is known about the evolution of CHC-based communication in species with simpler forms of social organization lacking specialized castes. Here we investigate factors shaping CHC variation in the orchid bee Euglossa dilemma, which forms casteless social groups of two to three individuals. We first assess geographic variation, examining CHC profiles of males and females from three populations. We also consider CHC variation in the sister species, Euglossa viridissima, which occurs sympatrically with one population of E. dilemma. Next, we consider variation associated with female behavioral phases, to test the hypothesis that CHCs reflect ovary size and social dominance. We uncover a striking CHC polymorphism in E. dilemma spanning populations. In addition, we identify a separate set of CHCs that correlate with ovary size, social dominance, and expression of genes associated with social behavior, suggesting that CHCs convey reproductive and social information in E. dilemma. Together, our results reveal complex patterns of variation in which a subset of CHCs reflect the social and reproductive status of nestmates.
The Impact of Earthquakes on Apartment Owners and Renters in Te Whanganui-a-Tara (Wellington) Aotearoa New Zealand

Apartment dwelling is on the increase in many cities in Aotearoa New Zealand, including those in earthquake-prone regions. Hence it is important that people working in disaster management and housing improve their understanding on how the living situations of apartment dwellers influence their disaster management practices. This knowledge is crucial for efforts to promote safety and preparedness. This paper explores what enables and constrains apartment dwellers in their ability to prepare for an earthquake. Eighteen people were interviewed who resided in Te Whanganui-a-Tara (Wellington) two years after the 2016 7.8 magnitude (Mw) Kaikōura earthquake. Of central concern was people’s ability to prepare for disasters and access knowledge about building and structural safety and how this knowledge mattered to what apartment dwellers were able to prepare for. We found that the agency to prepare was dependent on whether people owned or rented their dwellings. We report on participant accounts of dealing with body corporations, landlords, emergency kits, other emergency items, and evacuation plans.
A fuzzy synthetic evaluation of capabilities for improving supply chain resilience of industrialised construction: a Hong Kong case study

Abstract Inspired by multiple benefits, including competitive advantages from developing resilient supply chains, this study was designed for the development of effective assessment models to evaluate Supply Chain Capabilities (SCC), improving resilience in Industrialised Construction (IC) in one of the high-density cities: Hong Kong (HK). First identifying appropriate SCC, this study aimed to develop multi-stage-mathematical models to evaluate the adoption of SCC of IC in HK. Experts’ judgements were solicited and analysed using fuzzy synthetic evaluation. Forty-one measurement items were grouped under nine critical SCC components, and their ‘importance’ and ‘current practice’ indices were determined. The importance index of SCC is high, spotlighting the significance of the contribution of SCC to resilience whereas the current practice index is comparatively low, highlighting the dire need to bridge this gap with capability improvements. To the authors' knowledge, these evaluation models are the first set of structured models designed to assess SCC of IC, providing valuable insights to practitioners for well-informed decision-making in formulating strategies to initiate and nurture resilient supply chains in IC in HK.
Numerical Analysis of Hybrid Steel Beams with Trapezoidal Corrugated Web Nonwelded Inclined Folds

Hybrid beams provide the opportunity to implement characterized steel sections by recruiting materials based on yield strength and the type of applied stress. Previous studies demonstrated that steel beams with a trapezoidal corrugated web (SBCWs) were affected by both fatigue cracks initiated along the inclined fold (IF) and the maximal additional stress located in the middle of the IFs. This paper presents a numerical study of hybrid SBCWs and nonwelded IFs. Numerical simulation is presented using the finite element (FE) method with the aid of the ANSYS software package. Three-dimensional FE models were developed considering the nonlinear properties of materials and geometric imperfection and validated using five hybrid specimens that were fabricated and tested experimentally by the authors. The load-deflection behavior and failure mechanism of the numerical results were in good agreement with the experimental results. The comparison of the FE models and the experimental results shows the good capability of the FE model to be used as a base for the parametric study. The parametric study focused on the effect of web thickness, flange thickness, web height, and flange and web steel grades. Furthermore, parametric studies are conducted to investigate the effects of the number and depth of the stiffeners on the behavior of hybrid SBCWs. We concluded that the flange thickness, web thickness, web height, and steel grades of flanges significantly affect the capacity and failure mode of hybrid SBCWs. We also concluded that the flange stiffeners have a significant effect on the overall behavior, toughness, and load capacity of SBCWs. Finally, a new equation is proposed to anticipate the shear capacity of SBCW nonwelded IFs based on the length of the welded horizontal fold.
Forestry Research in the Middle East: A Bibliometric Analysis

Research trends in the field of forestry have experienced a significant evolution in recent years. However, there has been little use of bibliometric analyses to assess academic organizations and individual researchers in this field of science. This study investigates the progress of forestry research in Iran, Israel, and Turkey based on a bibliometric analysis of 2482 documents published between 2005 and 2019 and indexed in the Web of Science (WoS) scientific information platform. The countries were analyzed and compared in terms of the number of documents, the number of citations, the mean number of citations per document, the h-index, the share of funded articles, and several other metrics. A complete keyword network with graphical visualization and cluster analysis was also used for depicting the most frequent keywords used by the authors from these three countries. The results showed that the number of publications on forestry research grew steadily during the study period. Turkey, with 1529 documents, was the most active in publishing research in the field of forestry, followed by Iran (726 documents) and Israel (219 documents). Turkey’s publications received 11,220 citations with a cooperation coefficient (CC) of 0.587 that revealed a strong relationship between international collaboration with the USA, Germany, and Italy, and the number of citations, such that the articles with co-authors affiliated to foreign institutions were cited far more often than the articles with Turkish authorship. Although Iran (CC = 0.680) and Israel (CC = 0.706) recorded more activities in international collaboration than Turkey, their publications received much lower citations (Iran’s citations = 4433, Israel’s citations = 3939). Israel had 136 articles (62%) that received research funding, followed by Turkey and Iran with 604 (39%) and 284 (38%) articles. Nine out of the ten most popular journals among Israeli researchers were ranked as quartiles 1 and 2 in the forestry category, whereas Iranian and Turkish researchers mostly published in fewer journals ranked as quartiles 1 and 2. The most frequent keywords (i.e., topics) were species, condition, forest, and tree. Insights provided here can help balance research activities towards publishing more informed and effective scientific articles.
APPLICATION FRAUD PENTAGON FOR DETECTING SYMPTOMS OF SHORTFUL FINANCIAL STATEMENTS

The purpose of this study is to determine the effect of fraud pentagon toward fraudulent financial reporting sympton using modified Jones model to the mining companies. The method of sampling used purposive sampling method. The sample consists of 30 companies was listed on the Indonesia Stock Exchange in 2013-2016. The result of this research concluded that pressure which proxied by financial target and financial stability has a positive and significant effect on fraudulent financial reporting. Opportunity has a negative and significant effect on fraudulent financial reporting. Rationalization, capability, and arrogance has not significant effect on fraudulent financial reporting.
Changes in Hydrophobic Interactions among Gluten Proteins during Dough Formation

In this study, changes in hydrophobic interactions among gluten proteins were analyzed during dough mixing. Size-exclusion high-performance chromatography and two-dimensional fluorescence difference gel electrophoresis were performed on proteins extracted with 1-propanol by weakening the hydrophobic interaction. The amount of proteins extracted with 30% 1-propanol increased from the start of mixing to peak consistency, suggesting that the hydrophobic interactions among the strongly aggregated proteins weakened and resulted in disaggregation. The amount of proteins extracted with 10% 1-propanol decreased during hydration, indicating that these proteins aggregated through relatively weak hydrophobic interactions. The proteins that extractability decreased were mainly low molecular weight glutenin, α-gliadin, and γ-gliadin. The amount of monomeric proteins extracted with 30% 1-propanol decreased after peak consistency. The decreased protein was mainly ω-gliadin, indicating that ω-gliadin aggregated with other proteins through hydrophobic interactions. A front-face fluorescence analysis was performed on the dough with the addition of 8-anilino-1-naphthalenesulfonic acid or thioflavin T. The fluorescence intensity increased as a result of exposure to the hydrophobic groups of the gluten proteins and the formation of protein aggregates during dough mixing. These results indicate the importance of hydrophobic interactions in dough formation.
Effects of Elevated CO2 and Nitrogen Loading on the Defensive Traits of Three Successional Deciduous Broad-Leaved Tree Seedlings

To elucidate changes in the defensive traits of tree seedlings under global environmental changes, we evaluated foliar defensive traits of the seedlings of successional trees, such as beech, oak, and magnolia grown in a natural-light phytotron. Potted seedlings were grown under the combination of two CO2 concentrations (360 vs. 720 ppm) and two nitrogen (N) treatments (4 vs. 15 kg N ha−1 yr−1) for two growing seasons using quantitative chemical analyses and anatomical method. We hypothesized that the effects of CO2 and N depend on the successional type, with late successional species providing greater defense of their leaves against herbivores, as this species exhibits determinate growth. Beech, a late successional species, responded the most to both elevated CO2 concentration (eCO2) and high N treatment. eCO2 and low N supply enhanced the defensive traits, such as the high leaf mass per area (LMA), high carbon to N ratio (C/N ratio), and increase in the concentrations of total phenolic and condensed tannin in agreement with the carbon–nutrient balance (CNB) hypothesis. High N supply decreased the C/N ratio due to the high N uptake in beech leaves. Oak, a mid–late successional species, exhibited different responses from beech: eCO2 enhanced the LMA, C/N ratio, and concentration of total phenolics of oak leaves, but only condensed tannin increased under high N supply. Magnolia did not respond to all treatments. No interactive effects were observed between CO2 and N supply in all species, except for the concentration of total phenolics in oak. Although the amounts of phenolic compounds in beech and oak varied under eCO2 and high N treatments, the distribution of these compounds did not change. Our results indicate that the changes in the defensive traits of forest tree species under eCO2 with N loading are related to the successional type.
Robotic total gastrectomy for carcinoma in the remnant stomach: a comparison with laparoscopic total gastrectomy

Abstract Background Total gastrectomy for carcinoma in the remnant stomach (CRS) remains a technically demanding procedure. Whether robotic surgery is superior, equal, or inferior to laparoscopic surgery in patients with CRS is unclear. This study was designed to compare the efficacy and safety of robotic total gastrectomy (RTG) and laparoscopic total gastrectomy (LTG) for the treatment of CRS. Methods In this cohort study, we retrospectively analysed the data from patients who underwent RTG or LTG for CRS at Southwest Hospital (Chongqing, China) between May 2006 and October 2019. The surgical outcomes, post-operative complications, and survival outcomes between the two groups were compared. Results Compared with LTG, RTG was associated with similar effective operation time (272.0 vs 297.9 min, P = 0.170), higher total costs (105,967.2 vs 81,629.5 RMB, P < 0.001), and less estimated blood loss (229.2 vs 288.8 mL, P = 0.031). No significant differences were found between the robotic and laparoscopic groups in terms of conversion rate, time to first flatus, time to first soft diet, post-operative hospital stay, post-operative complications, R0 resection rate, and number of retrieved lymph nodes (all P > 0.05). The 3-year disease-free survival and 3-year overall survival rates were comparable between the two groups (65.5% vs 57.5%, P = 0.918; 69.0% vs 60.0%, P = 0.850, respectively). Conclusions RTG is a safe and feasible procedure for the treatment of CRS and could serve as an optimal treatment for CRS.