Miracle-dz/UniFAR-FTUs huggingface dataset:
Viral and cellular determinants of equine infectious anemia virus replication in primary equine macrophage cultures in vitro

52 Introduction 53 Materials and Methods 55 Animals and cells 55 Activation and infection of HMC 56 Virus replication 56 TNF-a bioassay 57 Isolation and amplification of proviral DNA 58 Isolation and amplification of viral mRNA species 59 Results 60 Dose-dependent relationship of endotoxin treatment and EIAV replication 60 Effects of endotoxin treatment on EIAV reverse transcription 61 Detection of EIAV mRNA transcripts from HMC 62 Effects of macrophage activation on the production of EIAV mRNAs 65 Discussion 68 Acknowledgements 73 Literature Cited 73 GENERAL CONCLUSION 91 ADDITIONAL LITERATURE CITED 93 APPENDIX A. DEVELOPMENT OF AN EQUINE MACROPHAGE CELL LINE 102 APPENDIX B. IMPORTANCE OF HOST CELL SPECIFICITY IN EIAV TRANSCRIPTION . 105
A Meta-Surface Antenna Array Decoupling (MAAD) Design to Improve the Isolation Performance in a MIMO System

In this paper, a design to reduce the mutual coupling between two closely MIMO antennas is presented. A metasurface superstrate consisting of periodic circular split ring resonator (CSRR) elements is placed above the coupled two-element patch antennas to improve the isolation performance. The propagation of the electromagnetic wave from antenna 1 to antenna 2 causing mutual coupling will be blocked since the loading of metasurface, which can be considered as a negative-permeability medium. First, the size of the CSRR element is determined by properly designing the range of negative permeability in the desire band. Thereafter, a decoupled MIMO array with a high isolation performance is realized with an intolerable matching curve. Then, some measures are employed on each patch to enhance the matching performance, such as etching slots and loading short probes on the patches. Next, two prototypes for the coupled and decoupled arrays are fabricated and measured to verify the improvement of the isolation performance. Measured results show that the value of $\vert \text{S}21\vert $ for the decoupled array has been greatly improved from −8 dB to less than −20 dB within the entire working band of 5.58-6.0 GHz. Meanwhile, the match bandwidth of $\vert \text{S}11\vert < -15$ dB for the decoupled array is approximately 420 MHz, which has also been improved in the desire band compared with the coupled array. In addition, the measured gains for the decoupled array are improved by approximately 1.8 dB as compared to the coupled array, whereas the efficiencies are increased by 16% which is higher than the coupled array. Moreover, the envelope correlation coefficient (ECC) for the decoupled array is reduced from 0.17 to 0.06 within the entire band of interest. Therefore, all measured results demonstrate that the proposed MAAD design is a good candidate for the improvement of MIMO antenna arrays.
8.1 Lakefield and Mobility Compute: A 3D Stacked 10nm and 22FFL Hybrid Processor System in 12×12mm2, 1mm Package-on-Package

The Lakefield processor combines heterogeneous 3D die stacking also called Foveros, with hybrid computing to enable a new class of small form factor mobile products. The stacked die and implementation of the 3D package with PoP memory is shown in Fig. 8.1. 1. The compute die is on Intel 10nm+ for power-performance and includes the CPU, GPU, IPU, memory and display engine based on IP from the Icelake product family. It includes one Core™ and four Atom™ cores in a hybrid configuration connected using a cache-coherent fabric. Both core types are exposed to the operating system which selects the best core depending on the performance and power characteristics of the workload. The memory subsystem supports LPDDR4X PoP in a 4×16 configuration. The base die is on Intel 22FFL and contains the chipset functionality including PCIe Gen3, USB type-C, storage, audio and a sensor hub. Combining 10nm and 22FFL in 3D enables a large dynamic range of performance and power modes. The 3D dies communicate with a low-power inter-die I/O called the Foveros Die Interface (FDI). The power delivery has been optimized to leverage a PMIC-based power delivery compared to previous to reach the low power and small form factors.
Effects of occupational lead exposure on testosterone secretion

This study aims the determination of the relationship between blood lead levels (BLL) and reproductive hormones in workers with occupational lead (Pb) exposure. 58 workers who visited Ankara Occupational and Environmental Diseases Hospital between 2013 and 2017 and had a BLL of > 5 μg/dL and no infertility problem, were included in the study as the case group. The workers who have a chronic disease and use prescribed or herbal medicine were excluded. 63 healthy office workers with no heavy metal exposure at the workplace were selected as the control group. BLL, total testosterone (TT), free testosterone (FT), alanine aminotransferase (ALT), aspartate aminotransferase (AST), thyroid stimulating hormone (TSH), triiodothyronine (T3), thyroxine (T4), uric acid, creatinine, complete blood count (CBC), prolactin (PRL), follicle stimulant hormone (FSH), luteinizing hormone (LH) levels were examined and the occupational anamnesis of the workers were taken. As a percentage, 47.9 % (n=58) of 121 persons (all males) was the study group with Pb exposure and 52.1 % (n=63) were the control group. While the BLL was 34,20 μg/dL in the exposed group, it was 1,82 μg/dL in the control group (p
25.8 A Near- Threshold-Voltage Network-on-Chip with a Metastability Error Detection and Correction Technique for Supporting a Quad-Voltage/Frequency-Domain Ultra-Low-Power System-on-a-Chip

Emerging embedded systems, such as autonomous robots/vehicles, demand a new system-on-a-chip (SoC) that is ultra-low power (mW or even sub-mW level) but highly robust. Such an SoC typically integrates heterogeneous building blocks for supporting a range of features, each ideally operating in an independent voltage and frequency (V/F) domain [1]. In such an architecture, a network-on-chip (NoC) has played a key role to enable high-speed and energy-efficient networking. However, it is increasingly challenging to meet a robustness target since each V/F domain uses a significantly different voltage, e.g., from nominal 1V to near-threshold voltage (NTV), and clock frequency, e.g., from hundreds of MHz to sub-MHz. Furthermore, any two clocks may have uncertain and time-varying phase and frequency relationships. These properties significantly worsen robustness, particularly metastability, in an NoC.
Acoustic-Prosodic and Lexical Cues to Deception and Trust: Deciphering How People Detect Lies

Humans rarely perform better than chance at lie detection. To better understand human perception of deception, we created a game framework, LieCatcher, to collect ratings of perceived deception using a large corpus of deceptive and truthful interviews. We analyzed the acoustic-prosodic and linguistic characteristics of language trusted and mistrusted by raters and compared these to characteristics of actual truthful and deceptive language to understand how perception aligns with reality. With this data we built classifiers to automatically distinguish trusted from mistrusted speech, achieving an F1 of 66.1%. We next evaluated whether the strategies raters said they used to discriminate between truthful and deceptive responses were in fact useful. Our results show that, although several prosodic and lexical features were consistently perceived as trustworthy, they were not reliable cues. Also, the strategies that judges reported using in deception detection were not helpful for the task. Our work sheds light on the nature of trusted language and provides insight into the challenging problem of human deception detection.
The study of spectral changes in THz range in normal and pathological skin in vivo depending on the dehydration methods used

The terahertz (THz) attenuated total reflectance (ATR) imaging of normal and pathological skin under the action of various dehydration agents was carried out in vivo. Studies were conducted on animal models (the mouse), patients with diabetes, and healthy volunteers. For measurements, each animal was leaned against the ATR prism of the skin surface, and several locations in the skin of each animal were analyzed. Places on the skin for analysis were chosen so that the intensity spectra of the THz signal were practically the same for selected points. THz spectra measurements were carried out every 10 minutes within 45 minutes interval under the action of a dehydration agent. 40% glucose was shown to provide the most effective improving tissue optical clearing effect in the THz range.
Epidemiology of Helicobacter pylori infection in Kinh and Khmer Children in Mekong Delta, Vietnam

Background: Helicobacter pylori (H. pylori) infection varies among ethnic or racial groups. This study aimed to evaluate the seroprevalence and factors associated with H. pylori infection among Khmer and Kinh children living in the same natural and social conditions in Mekong delta, Vietnam. Methods and Findings: This cross-sectional study was conducted between October and December 2012 in the Mekong delta. We collected data using a structured questionnaire on social-economic and health status, lifestyle and living conditions from 683 Khmer and Kinh children aged between 6 months and 18 years. Additionally, data were collected from 913 adults of 485 households settling together in the same rural communes. All the participants in the study had H. pylori serology (i.e. ELISA) tested on blood samples obtained by venous puncture. H. pylori serology data were analyzed using χ2 test and logistic regression models. In our study, the overall H. pylori seroprevalence was 36.7% (32.1% in children from 6 months to 18 years versus 40.2% in adults (p<0.05), with a sharp increase in the prevalence around 3 years of age, without significant difference between Kinh and Khmer ethnics. Blood group B, absence of prejudicial habit of taking food by hand, good practice of hand washing after defecation were identified as protective factors for H. pylori infection [OR (95% CI): 0.50 (0.32-0.79), 0.48 (0.29-0.79), 0.79 (0.41-0.98); respectively]. In addition, H. pylori infection in mothers, in first sibling and in two first siblings in particular were found as high risk factors for H. pylori infection in children [OR (95% CI): 1.98 (1.12-3.18), 2.12 (1.25-4.12), 4.39 (2.81- 6.94); respectively]. Conclusions: Results of our study showed low and indifferent rates of H. pylori seropositivity in Kinh and Khmer children. Data from this study strongly suggest that environmental andindividual hygiene and some lifestyle practices should be improved to lower H. pylori infection in this population.
Prospective evaluation of causes of infertility at a tertiary care hospital

Background: Infertility is defined as the failure to achieve a clinical pregnancy after 12 months or more of regular unprotected sexual intercourse. Worldwide, its prevalence is approximately 8-12%. There are numerous factors such as anatomical, physiological, genetic, environmental and acquired factors that cause infertility. The aim of the present study was to determine the causes and clinical pattern of infertility in infertile couples in North West India.Methods: It was a hospital based observational study carried out on 211 infertile couples in reproductive age group attending infertility clinic of Sardar Patel Medical College and associated PBM Hospital, Bikaner, Rajasthan between September 2016-February 2017. Collection of data was performed by means of a specifically designed questionnaire, which apart from the demographic data also included questions concerning the causes of infertility. Cases of infertility diagnosed after detailed history, clinical examinations and laboratory tests were included.Results: Out of 211 infertile couples, female factor was predominant in 60.18%, male factor in 15.16%, unexplained in 15.16% while a combination of both factors was seen in 9.47% cases in our study. 33.17% women had ovulatory dysfunction diagnosed by menstrual history and ultrasonography. Tubal block was observed in 9.47% infertile women. 6.63% women had hypothyroidism and 1.89% infertile women were diagnosed to have endometriosis. Husband semen analysis was also done to assess male factor. Nearly 5.21% of their male partners suffered from oligospermia, 4.73% had azoospermia and oligoasthenospermia was observed in 3.79% male partners.Conclusions: Predominant cause of infertility can be reported in male or female partner or both so, either partner should be counselled and investigated properly. Our study reports a predominance of female factors as a cause of female infertility but male factors also accounted for a significant number of cases.
SURVEY OF KNOWLEDGE AND ATTITUDES OF HEAD NURSES REGARDING ORGAN TRANSPLANTATION

Organ transplantation is the only therapeutic option for some diseases. The knowledge and attitudes of nurses regarding organ transplantation are vital for their proactive role in recruiting potential donors. Several factors may have a positive or negative influence on their attitudes, the most relevant of which are their religion, level of education and duration of employment. The aim of this study was to ascertain the level of knowledge and attitudes of head nurses regarding organ donation and transplantation, and to identify the factors with positive or negative impact. The majority of head nurses do not have sufficient knowledge about the Serbian Transplantation Law (77.8%). Another major factor which influenced attitudes of head nurses regarding organ donation was their religion (70.4%), and only 14.8% of head nurses agreed to be registered as potential organ donors. Acta Medica Medianae 2017;56(4):38-44.
Predicting Knee Joint Instability Using a Tibio-Femoral Statistical Shape Model

Statistical shape models (SSMs) are a well established computational technique to represent the morphological variability spread in a set of matching surfaces by means of compact descriptive quantities, traditionally called “modes of variation” (MoVs). SSMs of bony surfaces have been proposed in biomechanics and orthopedic clinics to investigate the relation between bone shape and joint biomechanics. In this work, an SSM of the tibio-femoral joint has been developed to elucidate the relation between MoVs and bone angular deformities causing knee instability. The SSM was built using 99 bony shapes (distal femur and proximal tibia surfaces obtained from segmented CT scans) of osteoarthritic patients. Hip-knee-ankle (HKA) angle, femoral varus-valgus (FVV) angle, internal-external femoral rotation (IER), tibial varus-valgus (TVV) angles, and tibial slope (TS) were available across the patient set. Discriminant analysis (DA) and logistic regression (LR) classifiers were adopted to underline specific MoVs accounting for knee instability. First, it was found that thirty-four MoVs were enough to describe 95% of the shape variability in the dataset. The most relevant MoVs were the one encoding the height of the femoral and tibial shafts (MoV #2) and the one representing variations of the axial section of the femoral shaft and its bending in the frontal plane (MoV #5). Second, using quadratic DA, the sensitivity results of the classification were very accurate, being all >0.85 (HKA: 0.96, FVV: 0.99, IER: 0.88, TVV: 1, TS: 0.87). The results of the LR classifier were mostly in agreement with DA, confirming statistical significance for MoV #2 (p = 0.02) in correspondence to IER and MoV #5 in correspondence to HKA (p = 0.0001), FVV (p = 0.001), and TS (p = 0.02). We can argue that the SSM successfully identified specific MoVs encoding ranges of alignment variability between distal femur and proximal tibia. This discloses the opportunity to use the SSM to predict potential misalignment in the knee for a new patient by processing the bone shapes, removing the need for measuring clinical landmarks as the rotation centers and mechanical axes.
The Role of Interoception in the Pathogenesis and Treatment of Anorexia Nervosa: A Narrative Review

Anorexia nervosa (AN) is a psychiatric illness characterized by extreme overvaluation of weight and disturbed eating. Despite having the highest mortality rate of any psychiatric illness, the etiology and neurobiology of AN are poorly understood. A growing body of research has begun to elucidate the role of reward processing, as well as cognitive and limbic networks, in the symptomology of AN. However, these advances have so far failed to contribute therapeutically, suggesting a new understanding may be necessary. A disturbance in the interoceptive system, involved in perceiving and interpreting the physiological condition of the body, has recently been proposed as a central mechanism of pathology in AN, through links to hunger and satiety, risk prediction errors, emotional awareness, and body dysmorphia. This review summarizes the existing literature in order to clarify possible underlying mechanisms and proposes a novel model of the neuro-circuitry of AN. Detailed neuroanatomical studies and new methods for studying interoception may allow further refinement of this model and the development of improved treatment.
Actuation of untethered pneumatic artificial muscles and soft robots using magnetically induced liquid-to-gas phase transitions

Controlled volumetric expansion using magnetic induction enables actuation of pneumatic artificial muscles without valves or pumps. Pneumatic artificial muscles have been widely used in industry because of their simple and relatively high-performance design. The emerging field of soft robotics has also been using pneumatic actuation mechanisms since its formation. However, these actuators/soft robots often require bulky peripheral components to operate. Here, we report a simple mechanism and design for actuating pneumatic artificial muscles and soft robotic grippers without the use of compressors, valves, or pressurized gas tanks. The actuation mechanism involves a magnetically induced liquid-to-gas phase transition of a liquid that assists the formation of pressure inside the artificial muscle. The volumetric expansion in the liquid-to-gas phase transition develops sufficient pressure inside the muscle for mechanical operations. We integrated this actuation mechanism into a McKibben-type artificial muscle and soft robotic arms. The untethered McKibben artificial muscle generated actuation strains of up to 20% (in 10 seconds) with associated work density of 40 kilojoules/meter3, which favorably compares with the peak strain and peak energy density of skeletal muscle. The untethered soft robotic arms demonstrated lifting objects with an input energy supply from only two Li-ion batteries.
Heavy Caterpillar Distances for Rooted Labeled Unordered Trees

: In this paper, we introduce two heavy caterpillar distances between rooted labeled unordered trees ( trees , for short) based on the edit distance between the heavy caterpillars obtained from the heavy paths in trees. Then, we show that the heavy caterpillar distances provide the upper bound of the edit distance for trees, can be computed in quadratic time under the unit cost function and are incomparable with other variations of the edit distance.
Automatic Classification of French Spontaneous Oral Speech into Injunction and No-injunction Classes

: The injunctive values are of particular interest for many studies dealing with oral speech interactions, e.g. in automatic meaning processing or in the field of language pathology understanding and therapy. We propose in this paper an automatic classification system using a subset of the RAVIOLI database in order to evaluate the role of prosody in the definition of injunctive values. RAVIOLI is constituted of more than 100 hours wild massive oral spontaneous speech. This work is a preliminary study that exploits a subset of 197 injunction values that have been labelled as exploitable utterances by two linguistic experts augmented by 198 of non-injunctive utterances. Many feature types were considered for this study: some classical features employed in speech community for automatic speech recognition tasks (LPCC, MFCC and PLP with their associated dynamic features) and some prosodic features (pitch and energy, with their associated dynamic features). The results clearly show the importance of prosodic features for the classification of the utterances into injunction or no-injunction classes and particularly the predominance of the log energy feature.
Goal-based Evaluation of Text Mining Results in an Industrial Use Case

: Artiﬁcial intelligence boosted the interest in text mining solutions in the last few years. Especially in non-English-speaking countries, where there might not be clear market leaders, a variety of solutions for different text mining scenarios has become available. Most of them support special use cases and have strengths and weaknesses in others. In text or page classiﬁcation, standard measures like precision, recall, sensitivity or F1-score are prevalent. However, evaluation of feature extraction results requires more tailored approaches. We experienced many issues on the way to benchmarking feature extraction results from text, like whether a result is correct, partly correct, helpful or useless. The main contribution of this work is a method for designing a tailored evaluation procedure in an individual text extraction benchmark for one speciﬁc use case. In this context, we propose a general way of mapping the common CRISP-DM process to particularities of text mining projects. Furthermore, we describe possible goals of information extraction, the features to be extracted, suitable evaluation criteria and a corresponding customized scoring system. This is applied in detail in an industrial use case.
Update on Rehabilitation Protocol Following ACL Reconstruction

Anterior cruciate ligament lessions represent one of the most frequently met injuries of the knee, determining pain and instability and having a decisive impact over the patients functional level and quality of life. Regardless whether or not the decision of surgical intervention is made, patients with ACL tear are at higher risk of developing osteoarthritis, long term disability and an increased risk of additional meniscus tear. Literature data, although it offers a suffi cient amount of information on the subject, still presents debates on the advantages of one rehabilitation program over another. Achieving maximal range of motion as soon as possible is a main objective in ACL injuries, restrictions of mobility leading to prolonged rehabilitation periods. The are also discussions on the benefi ts of using open versus closed kinetic chain exercises, and also to what extend can the rehabititation program be accelerated in order to return the knee to the pre-injury state. The rehabilitation program must contain a multimodal approach composed of not only adapted kinetotherapy programs, but also associated modalities such as cryotherapy, neuromuscular stimulation, use of braces or hydrokinetotherapy in order to reduce pain and effusion and increase range of motion. The purpose of the present material is to analysis the existing data on the subject, and to evaluate the therapeutic benefi t of the rehabilitation modalities used in ACL injuries.
Sentiment analysis in Spanish tweets: Some experiments with focus on neutral tweets

We present different methods for Sentiment analysis in Spanish tweets: SVM based on word embeddings centroid for the tweet, CNN and LSTM.We analyze the results obtained using the corpora from the TASS sentiment analysis challenge, obtaining state of the art results in the performance of the classifiers. As the neutral category is the hardest one to classify, we focus in understanding the neutral tweets classification problems and we further analyze the composition of this class in order to extract insights on how to improve the classifiers.