Miracle-dz/UniFAR-FTUs huggingface dataset:
Current Status and Future Aspects of Stereotactic Body Radiotherapy and Immunotherapy in the Management of Recurrent Head and Neck Cancer

The rate of loco-regional recurrence and secondary primary tumors is high in patients with head and neck cancer (HNC). Although surgery is very effective in the management of these patients, total resection is rarely possible due to anatomic and functional constraints. In patients not amenable to surgery, chemoradiotherapy plays a major role and stereotactic body radiotherapy (SBRT) is the treatment of choice based on its advantage of high therapeutic ratio. Recent advances in immunotherapeutic agents also provide promising results in many tumor sites and may have advantages in the treatment of recurrent HNC. Concurrent use of these agents with SBRT is still being investigated.
INTERNAL FACTORS OF COMPANY RATING ON FOOD AND BEVERAGE COMPANIES LISTED ON THE INDONESIA STOCK EXCHANGE

This research aimed to examine the influence of internal factors on firm value. In this study the internal factors that profitability, dividend policy, and funding decisions. This study used six companies as a sample from a population of 14 manufacturing companies listed on Indonesian stock exchange in period of 2011-2015. The sample was determined by using purposive sampling. The results showed that profitability and funding decisions had positive effect on firm value, while dividend policy had a negative effect on firm value. The profitability, dividend policy, and funding decisions simultaneously had a positive effect on firm value. The value of the adjusted R2 of 0,798 indicated that the contribution of all the independent variables to account for the dependent variables was 79,8%.
LESSONS LEARNT FROM LIPID LOWERING TRIALS : OUR FUTURE APPROACH

Lipids and lipoproteins are associated with atherosclerosis in general and coronary atherosclerosis in particular. CHD is a multifactorial disease . LDL-c is a strong and independent risk factor for CHD based on robust evidence from epidemiological data and lipid lowering trials. CHD still remains the single most prevalent cause of mortality not only in developed countries but also in developing countries including India. Clearly we must improve our ability to identify and intervene in controlling these risks. The question ,of course ,is how best to do it. Many CHD risk factors can be improved . Nonlipid risk factors and environmental factors must also be addressed. We have learnt many lessons from the lipid lowering trials particularly LDL lowering using statins in the last few decades.
Comparing dividend policies between Germany and the Netherlands: a test of the life-cycle theory

This paper compares the dividend policies of German and Dutch firms on the basis of the life-cycle theory of dividends. Evidence for the life-cycle theory can be found for Germany whereas the Netherlands show no significant results for it but tend to pay out dividends in order to signal profitability. For Germany, the signaling theory as well as the clientele effect does not play a significant role in determining dividend policy. The life-cycle stages are determined by the earned/contributed capital mix which suggests that firms with high earned capital are mature and more likely to pay out (high) dividends. Germany and the Netherlands both pay out low dividends. The study in this paper indicates that dividend payout in both countries is also related to industry-specific characteristics. Supervisors: Henry van Beusichem, Xiaohong Huang
Halobacterium identification in saltworks of Gran Canaria (Canary Islands, Spain)

Article history Received: 11 November 2019 Accepted: 31 December 2019 Published Online: 28 February 2020 This work analyzes bacterial communities present in evaporation ponds of solar salterns of Gran Canaria and reveals specific organisms through molecular techniques. Solar salterns are protected areas in Canary Islands where salt is produced from sea water by solarand windpowered evaporation. Salt was an important product for ancient islanders who used it for a broad field of purposes, but also has a great importance in recent time for its implications in the island economy. Based on amplifications with specific primers for 16S ribosomal DNA (16S rDNA) and subsequent nested-PCR approaches, different amplicons were obtained, and analyzed in silico. A taxonomic classification was carried out through phylogenetic trees. Results revealed different bacteria according to the evaporation grade of crystallizer ponds in saline works. It is worthstanding the presence of the genus Halobacterium in all crystallizer ponds. This opens an interesting framework for further studies and continuative molecular characterization approaches of bacterial communities in solar salterns of Gran Canaria.
THE INTERNATIONALIZATION IN THE INNOVATION PROCESS IN INFORMATION AND COMMUNICATION TECHNOLOGY (ICT) BRAZILIAN STARTUPS

Objective: To understand how the innovation process is impacted by the internationalization strategy of the Brazilian ICT startups. Method: The multiple cases study was adopted with seven startups. The analysis was based on the concepts of internationalization strategy defined by Carneiro and Dib (2007) and the innovation process of Tidd and Bessant (2009). Data was collected through interviews with the founders of the startups, documental analysis and observation. Originality / Relevance: Internationalization and innovation are usually addressed separately and focused mainly in large companies. Studies connecting both themes are scarce in the academic literature. , especially in emerging countries. Results: The motivation, the choice of the country, the time to internationalization, what was internationalized and the way the startups arrived in other country impacted the innovation process of the startups. However, it was observed that the choice of the country and the form of entry contributed more to the innovation process of these nascent companies. Theoretical / methodological contributions: The academic contribution is the empirical observation of the innovation process, considering the internationalization, in startups in an emerging country. Through the results, eight propositions were brought up to path future studies about those themes. Social / management contributions: Based on the innovation process as a way for startups to be competitive this study contributes by identifying internationalization strategies that lead startups to the advancement of the innovation process. In this way, Brazilian ICT startups and public policies can support the development of these strategies.
DEVELOPMENT OF A NEW TEST BENCH DEDICATED TO ADHESI ON CHARACTERIZATION OF LUNAR DUST SIMULANTS IN SPACE ENVIRONMENT

Adhesion of dust to spacecraft surfaces is mainly d ue to two forces: electrostatic forces and the Van der Wa als force. This paper deals with the experimental characterization of the latter. A centrifugal syste m is developed to determine the adhesion force as a func tion of the dust and substrate properties. For lunar dus t simulant DNA-1 and for a technical substrate of uncontrolled roughness, the adhesion force ranges f rom 20 to 200 nN for particle size below 50 μm, which i s in relatively good agreement with the results of the literature. The role of surface roughness of both d ust and substrate is discussed.
THE DEPENDENCE ON CARBOHYDRATE FUELING FOR SUCCESSFUL HIGH-INTENSITY, ENDURANCE PERFORMANCE

• Carbohydrate (CHO) availability is fundamental for high-intensity endurance performance, contributing over 80% of the total energy expenditure via both muscle glycogen (~60%) and blood glucose (~20%) oxidation when working at intensities of 80% O 2 max and above. • The body’s finite CHO stores (~500 g) can sustain high-intensity endurance exercise for ~90 min. Therefore, the body aims to spare this limited CHO supply where possible and utilize fat substrates during submaximal exercise. • High-fat or ketogenic diets increase the utilization of fat substrates during prolonged, submaximal exercise but impair carbohydrate metabolism. Current evidence demonstrates that high-fat diets impair exercise economy and do not improve high-intensity performance. • Exogenous ketone drinks increase circulating ketones and reduce lactate production during high-intensity cycling. Preliminary evidence suggests a ketone monoester drink may improve cycling time-trial performance but a diester may impair performance. • Athletes should periodize CHO intake during training, including sessions with higher and lower CHO availability, to maximize skeletal muscle adaptations and align with the goals of the training session. • Athletes require CHO before and during competition to fuel the high-intensity, maximal efforts required in racing to support winning performances and recovery.
THE F. AND M. RIESZ THEOREM FOR C∗-ALGEBRAS

Our main result is a generalization of the F. and M. Riesz theorem to traced C∗-algebras containing an “analytic subalgebra”. A linear functional on such an algebra is called analytic if it vanishes on the analytic subalgebra. We prove that both the absolutely continuous and the singular part of the Lebesgue decomposition of an analytic linear functional are analytic and moreover that the singular part vanishes on the unit. This Theorem is used to study a distance formula related to Sarason’s theorem on the closedness of H∞ + C . Introduction. The F. and M. Riesz theorem [10] states that every analytic measure on the circle group is absolutely continuous with respect to the Haar measure. This result is among the deepest facts of classical harmonic analysis and is the basis for much of the work that has been done in this field since its publication in 1916. A rich environment where the ideas of classical harmonic analysis have been applied is the theory of operator algebras and, in special, the theory of non-selfadjoint algebras. A paper by Arveson [1] for example contains a generalization of the inner-outer factorization theorem for analytic functions as well as Jensen’s inequality to the context of certain operator algebras called sub-diagonal algebras. In the present paper we take another step in this direction proving an extension of the F. and M. Riesz theorem to C∗-algebras containing a special kind of non-selfadjoint sub algebras which we call analytic subalgebras. Analytic subalgebras are the C∗-counterparts of Arveson’s sub-diagonal algebras. Generalizations of the F. and M. Riesz theorem appear quite often in the literature. The reader will find related results in [6] and [7]. We believe nevertheless that ours is the first such result in a non-commutative context. Our desire to search for a generalized F. and M. Riesz theorem grew out of our interest in the theory of C∗-algebras of right ordered groups which, as much as Arveson’s theory of sub-diagonal algebras, presents a wide area where ideas of Classical Harmonic Analysis can be searched for. The precise problem that motivated the present work came up in connection with our previous work on Hankel matrices over right ordered goups [4] and is described as follows. Let G be a discrete right ordered group and denote by C∗ r (G) its reduced C ∗-algebra. Let CH∞ 0 (G) (resp. H ∞ 0 (G)) be the norm closed (resp. ultra-weakly closed) algebra of * Partially supported by CNPq, Brazil.
8. Tshweneagae.pmd

A substantial body of research has consistently concluded that children growing up with absentee fathers are at an increased risk of maladjustment. This paper argues that co-parenting can have both direct and indirect or mediated effects on children. Co-parenting has an added benefit of modelling dyadic skills that include proving mutual emotional support, influence, and amicable resolution of disputes. Through qualitative data obtained in 2009 from 45 final year students at the University of Botswana, the authors conclude that African personhood is a larger-than-self conception, which also includes more than the physical being and shows that young people raised in father-absent families view their personhood as inferior, less guarded, and incomplete, relative to that of their counterparts who were born and raised in married-couple families. Living a full quality life eludes youth who were raised by mothers only, affirming the importance of fathers in the personhood of any individual.
Identifying Cancers for CDK8/19 Inhibitor Therapy

CDK8 and CDK19 Mediator kinases are transcriptional co-regulators implicated in several types of cancer. Small-molecule CDK8/19 inhibitors have recently entered or are entering clinical trials, starting with breast cancer and acute myeloid leukemia (AML). To identify other cancers where these novel drugs may provide benefit, we queried genomic and transcriptomic databases for potential impact of CDK8, CDK19, or their binding partner CCNC. sgRNA analysis of a panel of tumor cell lines showed that most tumor types represented in the panel, except for some central nervous system tumors, were not dependent on these genes. In contrast, analysis of clinical samples for alterations in these genes revealed a high frequency of gene amplification in two highly aggressive subtypes of prostate cancer and in some cancers of the GI tract, breast, bladder, and sarcomas. Analysis of survival correlations identified a group of cancers where CDK8 expression correlated with shorter survival (notably breast, prostate, cervical cancers, and esophageal adenocarcinoma). In some cancers (AML, melanoma, ovarian, and others), such correlations were limited to samples with a below-median tumor mutation burden. These results suggest that Mediator kinases are especially important in cancers that are driven primarily by transcriptional rather than mutational changes and warrant an investigation of their role in additional cancer types.
Gender Differences in the Effects of Explicit Vocabulary Learning Strategies Training

Vocabulary knowledge is a building block in language learning, but many students struggle to learn new words regardless of their proficiency level. Various studies have demonstrated the efficacy of explicit instruction of vocabulary learning strategies (VLS). On the other hand, other studies have demonstrated that gender can affect a student’s use of language learning strategies including vocabulary learning strategies, and many of them have confirmed that females use a larger variety of strategies more often than their counterparts. The aim of this study was to shed light on gender difference as a variable for the influence of explicit VLS training. The participants were 109 Japanese EFL bioscience majors. They completed a questionnaire on vocabulary learning behavior before and after receiving explicit VLS training for 11 weeks. The questionnaire consisted of nine categories of items, two on metacognitive strategies, six on the use of cognitive and memory strategies, and one on overall use of VLS. The quantitative measures used a 5-point Likert scale and multiple-choice. The VLS training focused on four memory strategies, namely imagery, association, affix and grouping. The results from two-way repeated measures analysis of variance (ANOVA) with VLS training and gender as factors revealed that VLS training was effective in enhancing the participants’ use of metacognitive strategies, writing rehearsal, and grouping strategy, although significant gender differences were observed for writing and grouping strategies. The students’ written comments gave us insight into their perception of these strategies. Gender difference was also observed in the overall use of strategies.
Community and International Nutrition Treatment of Trichuris trichiura Infections Improves Growth, Spelling Scores and School Attendance in Some Children1Â«2

The effects of treating Trichuris trichiura infections were investigated in 407 Jamaican children age 6 to 12 y. The children were randomly assigned to receive treatment (albendazole) or a placebo. The outcome variables included growth, tests of reading, spelling and arithmetic, and school attendance. After 6 mo of treatment, there was no significant main effect on any of the outcomes. However, there were significant treatment-by-infection intensity interactions with spelling (P < 0.05) and body mass index (P < 0.01), and a significant treatment-by-stunting interaction with school attendance (P < 0.01). In spelling, the children with heavy infections showed improvements with treatment that approached significance (P = 0.06), whereas those with lower intensities did not. However, the children with lower infection intensities had in creased body mass index with treatment (P = 0.02), although there was no difference in children with heavy infections. In school attendance, the stunted children improved with treatment (P < 0.04), whereas there was no difference in the nonstunted children. These findings suggest that in the sample of Jamaican children ex amined, the treatment of T. trichiura was more likely to benefit school performance in children of poor nutritional status and those with heavy infections, and to improve weight gain in children with lighter infection intensities. J. Nutr. 125: 1875-1883, 1995.
FDI-Trade-Environment Linkages: Changing Flows Between EU (15), Enlarged EU (12) and Non-European Countries

The aim of the paper is threefold. Identification of the determinants of the FDI outflows from the EU (12) at the industry and regional level can be counted as the first, searching the nature (more specifically substitutability/complementarity relationship) of FDI–trade linkages between the countries/regions under consideration as the second and finally, analaysing the significance of environmental stringency differentials between these countries/regions on the outflow of FDI as the third aim. A panel econometric model is employed to analyse the relationships between variables and their level of significance with a given specific attention to the mining and manufacturing industries. The empirical analysis in this paper finds some evidence to suggest that in the case of EU (12) cost related factors are not the only cause of FDI outflows but potential demand matters as well at the industry level. Similar trends are observed at the regional level. However, particular characteristics of each region should also be underlined. The results associated with the environmental sensitivity seem to support the argument that overall environmental sensitivity significantly affects the FDI flows from the EU (12). Furthermore, substitutability relation between FDI outflows and exports is also found.
Early weight trends in preterm babies post discharge

LBW and prematurity are the second leading causes of infant mortality after congenital anomalies. Fortunately, in the recent decade, perinatal mortality has significantly reduced in developed countries following increased use of prenatal steroids, surfactant and noninvasive and invasive respiratory support. Postnatal growth of infants is different from in-utero growth for various reasons which include extrauterine environment and varied nutritional requirement. The further growth of the preterm in terms of weight gain is extremely crucial for their survival and wellbeing. The care of LBW infants has improved over the years with continuing changes in medical and nutritional management. Despite this improvement, they continue to suffer growth lag during ABSTRACT
The Unexpected Downside of Paying or Sending Messages to People to Make Them Walk

People do not exercise as much and as regularly as they should. To support users in adopting healthy exercise routines, app designers integrate persuasive techniques in their apps. In this study, we focus on two of these techniques, i.e., offering tangible rewards and sending motivational messages to users. Past research has demonstrated the effects of these techniques in nudging recipients to increase their physical activity levels. However, the effect of these interventions on the intrinsic motivation of the participants has not yet been studied. We conducted a 10-month study involving 208 participants; this research consisted of a 3-month baseline (pre-phase), a 4-month experiment and a 3-month follow-up (post-phase). The participants were randomly assigned to one of the following three interventions: either they receive money ((i.) through a fixed incentive or (ii.) a lottery), or (iii.) informative messages. Their daily goal was to walk 10K steps. Through their smart phones, we recorded how many steps they walked every day. These interventions had no effect on the main outcome variable (i.e., the number of steps). However, the manipulations produced a detrimental effect on the intrinsic motivation of the participants, measured through a standardized questionnaire. This negative effect extended into the follow-up period. Our study reveals that tangible rewards and motivational messages decrease the intrinsic motivation of the participants, hence their connected physical activity. In our findings, we highlight the importance of intrinsic motivation in setting up healthy exercise routines that will be carried on autonomously by the participants after the period of the intervention. Finally, we present implications for the design of persuasive apps.
Toward contraceptive self-reliance in Turkey: results from a pilot test of a cost-sharing mechanism. Full report.

The pilot study on testing a donation policy for achieving contraceptive self-reliance in turkey was conducted jointly by the Turkish Ministry of Health General Directorate of Mother and Child Health and Family Planning and the POLICY Project. This report includes findings from a pilot study that: -Assessed the attitudes and behavior of public sector family planning clients when asked to make a donation for contraceptives received at MOH facilities. Specifically it assessed how the donation policy affected demand for family planning services at MOH facilities -Assessed the attitude of MOH providers and administrators toward the targeting plan and their level of compliance with the elements of the plan. -Tested the mechanism designed for the targeting plan. -Collected data for use in estimating national revenue potential and determining optimum donation levels. (authors)
Linear and Nonlinear Growth Determinants: The Case of Mongolia and its Connection to China

We investigate growth determinants for Mongolia as a small emerging economy considering China as its large neighbor. Our causality analysis during January 1992 to August 2017 reveals significant linear and nonlinear relationships in growth explanation. China’s GDP and coal prices, together with some of their linear and nonlinear lagged components, predict Mongolia’s GDP, where a one percent increase in China’s GDP relates to an increase in Mongolia of 1.5 percent. Current exchange rates and the nonlinear components of lagged levels of consumer prices also explain growth. Our results underline the role of macroeconomic drivers of growth in emerging economies.
Cytological Evaluation of Premalignant and Malignant Oral Lesions by Oral Brush Cytology

Context Oral brush cytology is easy, chair side non invasive, painless test that can be used to evaluate any suspicious lesion including common small white and red oral lesions to rule out dysplasia. The use of brush cytology without computer-assisted analysis using toothbrush is less expensive and may have applications in resource-challenged areas and could be a risk-free method of evaluating oral lesions.