Miracle-dz/UniFAR-FTUs huggingface dataset:
Coping profiles of adolescent football players and association with interpersonal coping: Do emotional competence and psychological need satisfaction matter?

Using a person-centered approach, the present study aimed to investigate the coping profiles of adolescent football players involved in elite football training centers. The purposes were to (1) identify coping profiles based on the reported use of multiple coping strategies in response to competitive stress, (2) explore whether emotional competencies and psychological need satisfaction would predict coping profile membership, and (3) examine the extent to which coping profiles were differently associated with individual and team perceived stress, interpersonal coping, and subjective team performance, as well as demographic characteristics. A sample of 416 young French football players (males = 282; females = 134; Mage = 16.2; SDage = 1.2) from 12 elite football training centers participated in this study. Latent profile analysis results yielded three coping profiles allowing players to be grouped according to their preferences for a combined use of certain strategies (i.e., low copers, high disengaged copers, and high task copers). Results provided further insight into each coping profile membership by indicating the role played by intrapersonal emotional competence and psychological need satisfaction. Finally, differences between coping profiles have been shown in terms of individual perceived stress intensity, interpersonal coping approach, and gender. These findings provide a deeper understanding of adaptive coping profiles within a population of adolescent football players involved in elite training centers. Implications for developing and tailoring psychoeducational interventions for adolescent football players exhibiting a maladaptive coping profile (i.e., disengagement-oriented coping profile) are considered.
Primary failure of thoracic epidural analgesia: revisited

Primary failure of thoracic epidural analgesia (TEA) remains an important clinical problem, whose incidence can exceed 20% in teaching centers. Since loss-of-resistance (LOR) constitutes the most popular method to identify the thoracic epidural space, the etiology of primary TEA failure can often be attributed to LOR’s low specificity. Interspinous ligamentous cysts, non-fused ligamenta flava, paravertebral muscles, intermuscular planes, and thoracic paravertebral spaces can all result in non-epidural LORs. Fluoroscopy, epidural waveform analysis, electrical stimulation, and ultrasonography have been proposed as confirmatory modalities for LOR. The current evidence derived from randomized trials suggests that fluoroscopy, epidural waveform analysis, and possibly electrical stimulation, could decrease the primary TEA failure to 2%. In contrast, preprocedural ultrasound scanning provides no incremental benefit when compared with conventional LOR. In the hands of experienced operators, real-time ultrasound guidance of the epidural needle has been demonstrated to provide comparable efficacy and efficiency to fluoroscopy. Further research is required to determine the most cost-effective confirmatory modality as well as the best adjuncts for novice operators and for patients with challenging anatomy. Moreover, future trials should elucidate if fluoroscopy and electrical stimulation could potentially decrease the secondary failure rate of TEA, and if a combination of confirmatory modalities could outperform individual ones.
Germline testing of BRCA1, BRCA2, PALB2 and CHEK2 c.1100delC in 1514 triple negative familial and isolated breast cancers from a single centre, with extended testing of ATM, RAD51C and RAD51D in over 400

Background The identification of germline pathogenic gene variants (PGVs) in triple negative breast cancer (TNBC) is important to inform further primary cancer risk reduction and TNBC treatment strategies. We therefore investigated the contribution of breast cancer associated PGVs to familial and isolated invasive TNBC. Methods Outcomes of germline BRCA1, BRCA2 and CHEK2_c. 1100delC testing were recorded in 1514 women (743—isolated, 771—familial), and for PALB2 in 846 women (541—isolated, 305—familial), with TNBC and smaller numbers for additional genes. Breast cancer free controls were identified from Predicting Risk Of Cancer At Screening and BRIDGES (Breast cancer RIsk after Diagnostic GEne Sequencing) studies. Results BRCA1_PGVs were detected in 52 isolated (7.0%) and 195 (25.3%) familial cases (isolated—OR=58.9, 95% CI: 16.6 to 247.0), BRCA2_PGVs in 21 (2.8%) isolated and 67 (8.7%) familial cases (isolated—OR=5.0, 95% CI: 2.3 to 11.2), PALB2_PGVs in 9 (1.7%) isolated and 12 (3.9%) familial cases (isolated—OR=8.8, 95% CI: 2.5 to 30.4) and CHEK2_c. 1100delC in 0 isolated and 3 (0.45%) familial cases (isolated—OR=0.0, 95% CI: 0.00 to 2.11). BRCA1_PGV detection rate was >10% for all familial TNBC age groups and significantly higher for younger diagnoses (familial: <50 years, n=165/538 (30.7%); ≥50 years, n=30/233 (12.9%); p<0.0001). Women with a G3_TNBC were more likely to have a BRCA1_PGV as compared with a BRCA2 or PALB2_PGV (p<0.0001). 0/743 isolated TNBC had the CHEK2_c. 1100delC PGV and 0/305 any ATM_PGV, but 2/240 (0.83%) had a RAD51D_PGV. Conclusion PGVs in BRCA1 are associated with G3_TNBCs. Familial TNBCs and isolated TNBCs <30 years have a >10% likelihood of a PGV in BRCA1. BRCA1_PGVs are associated with younger age of familial TNBC. There was no evidence for any increased risk of TNBC with CHEK2 or ATM PGVs.
Bearing witness poetically in a pandemic: documenting suffering and care in conditions of physical isolation and uncertainty

The COVID-19 crisis is still affecting millions of people worldwide. However, government and mass media attention to the continuing loss of life, severe illness and prolonged effects of COVID-19 has subsided, rendering the suffering of those who have become ill or disabled, or who have lost loved ones to the disease, largely hidden from view. In this article, we employ autoethnographic poetic inquiry from the perspective of a mother/carer whose young adult daughter became critically ill and hospitalised after becoming infected while the mother herself was isolating at home due to her own COVID-19 diagnosis. The first author created a poem from notes she had made in a journal from telephone conversations and messages with the healthcare providers caring for her daughter. The second author responded to the poem, identifying the feelings and meanings it surfaced. Together, the authors draw on scholarship discussing concepts of uncertainty, liminality, moral distress, bearing witness and illness narratives to reflect on how autoethnographic poetic inquiry can document and make visible COVID-19-related suffering.
AMEP_A_185780 645..651

Seyed Jalil Seyedi-Andi Fatemeh Bakouei Hajar Adib Rad Soraya Khafri Asgari Salavati 1Social Determinants of Health Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Islamic Republic of Iran; 2Infertility and Reproductive Health Research Center, Health Research Institute, Babol, Islamic Republic of Iran; 3Department of Midwifery, School of Medicine, Babol University of Medical Sciences, Babol, Islamic Republic of Iran; 4Department of Statistic and Epidemiology, School of Medicine, Babol University of Medical Sciences, Babol, Islamic Republic of Iran; 5Department of Psychiatrics, Babol University of Medical Sciences, Babol, Islamic Republic of Iran Purpose: Self-efficacy not only concentrates on specialty and competence but also considers the individual beliefs about what is obtainable. This study aimed to determine the effect of demographic and socioeconomic variables on self-efficacy status in students of Babol University of Medical Sciences. Methods: This cross-sectional study was performed on 350 students of Babol University of Medical Sciences in 2016. The clustering-systematic random multi-stage sampling method was used for sampling. Data were collected using two demographic and socioeconomic status questionnaires as well as a General Self-Efficacy Scale (GSE). The collected data were analyzed using SPSS software version 18 at a significance level of P≤0.05. Results: The mean age of students was 21.37±2.28 years, and most participants were female (58%). The highest number of students (65.7%) studied at the bachelor level. The students’ mean total self-efficacy score was 61.08±8.67 and ranged between 25 and 82. There was a significant statistical relationship between self-efficacy index and variables such as family income, school, and grade. The highest positive relationship was observed in proper family income and the mean grade was higher than 16 (P≤0.001). Students in Rehabilitation and Paramedical Schools had lower self-efficacy compared to medical and paramedical students. Conclusion: Students’ self-efficacy is dependent on various socioeconomic and educational factors such as family income, academic grade, academic year, and school; so recognizing these factors can play an important and effective role in improving students’ academic achievement. Therefore, it is recommended to use effective educational interventions in colleges with students’ active role in different fields in order to promote students’ selfefficacy and improve their self-esteem and self-confidence.
Effect of Repetitive Transcranial Magnetic Stimulation on Effect of Repetitive Transcranial Magnetic Stimulation on Essential Tremors Essential Tremors

Background: The effects of cerebellar low-frequency repetitive transcranial magnetic stimulation (rTMS) in individuals suffering from essential tremor (ET) are controversial. Aim of The Work: To evaluate repetitive transcranial magnetic stimulation (rTMS) can help people with essential tremors. Patients and Methods: This case study involved 30 subjects divided into an active group of 15 ET patients and a sham group of another 15 ET patients who were treated in tertiary care at Al-Hussein and Sayed Galal Hospitals, Al-Azhar University. The Fahn, Tolosa, Marin (FTM) Tremor Rating Scale has been used to evaluate and scale tremors at baseline, as well as a day, one month, two months, and three months following the (sham and active) repetitive transcranial magnetic stimulation sessions. Results: The results of this study showed that repeated active rTMS over the cerebellum enhanced total and specific subcores (tremor, drawing, and functional disability). The influence lasted for 3 months following the final session. The sham group's total and specific FTM subcores (tremor, drawing, functional disability) showed no significant differences. Conclusion: For patients suffering from severe essential tremor, cerebellar rTMS can be an effective therapy choice.
Weak-to-Strong Generalization: Eliciting Strong Capabilities With Weak Supervision

Widely used alignment techniques, such as reinforcement learning from human feedback (RLHF), rely on the ability of humans to supervise model behavior - for example, to evaluate whether a model faithfully followed instructions or generated safe outputs. However, future superhuman models will behave in complex ways too difficult for humans to reliably evaluate; humans will only be able to weakly supervise superhuman models. We study an analogy to this problem: can weak model supervision elicit the full capabilities of a much stronger model? We test this using a range of pretrained language models in the GPT-4 family on natural language processing (NLP), chess, and reward modeling tasks. We find that when we naively finetune strong pretrained models on labels generated by a weak model, they consistently perform better than their weak supervisors, a phenomenon we call weak-to-strong generalization. However, we are still far from recovering the full capabilities of strong models with naive finetuning alone, suggesting that techniques like RLHF may scale poorly to superhuman models without further work. We find that simple methods can often significantly improve weak-to-strong generalization: for example, when finetuning GPT-4 with a GPT-2-level supervisor and an auxiliary confidence loss, we can recover close to GPT-3.5-level performance on NLP tasks. Our results suggest that it is feasible to make empirical progress today on a fundamental challenge of aligning superhuman models.
Reproductive Medicine; Endocrinology and Infertility

OBJECTIVE: In this study, we aimed to investigate the effect of sildenafil, acting as an anti-oxidant on the ischemic rat ovarian torsion model by pointing out ovarian reserve via AMH levels which is the best marker for oocyte pool. STUDY DESIGN: This study is an experimental animal study conducted according to the principles of the Declaration of Helsinki. Twenty-seven rats were assigned into three groups, each consisting of nine individuals. Group 1: Sham operation (laparotomy only) was performed. Group 2: The torsion group had bilateral torsion and detorsion of the ovaries. Group 3: In Sildenafil and torsion group the rats received 0.7 mg/kg sildenafil (Viagra, Pfizer, New York, ABD) intraperitoneally one hour before torsion and detor-sion operation. One month after the initial operation, blood was drawn via the intra-cardiac route, and serum antimullerian hormone (AMH) concentrations were studied. RESULTS: The mean weights of the rats were similar 224 g, 229 g, and 222 g for groups 1, 2, and 3 respectively. Only one rat from Group 2(T/D) died during the experiment leaving eight rats for analysis. The mean value for AMH was 24.9227±12.19124 ng/ml and the mean value for weight was 226.22±19.200. The differences in AMH groups were not statistically significant (p=0.873) CONCLUSIONS: As a result, as is shown in our study, the ovarian reserve may not be influenced by ischemia developed by ovarian torsion or any influences could not change AMH levels. Sildenafil which was given to the rats before detorsion to protect against reperfusion ischemia was found to be ineffective on ovary reserve according to AMH assessment.
Using Isotopes to Constrain Water Flux and Age Estimates in Using Isotopes to Constrain Water Flux and Age Estimates in Snow-Influenced Catchments Using the STARR (Spatially Snow-Influenced Catchments Using the STARR (Spatially Distributed Tracer-Aided Rainfall–Runoff) Model Distributed Tracer-Aided

Tracer-aided hydrological models are increasingly used to reveal fundamentals of runoff generation processes and water travel times in catchments. Modelling studies integrating stable water isotopes as tracers are mostly based in temperate and warm climates, leaving catchments with strong snow inﬂuences underrepresented in the literature. Such catchments are challenging, as the isotopic tracer signals in water entering the catchments as snowmelt are typically distorted from incoming precipitation due to fractionation processes in seasonal snowpack. We used the Spatially distributed Tracer-Aided Rainfall– Runoff (STARR) model to simulate ﬂuxes, storage, and mixing of water and tracers, as well as estimating water ages in three long-term experimental catchments with varying degrees of snow inﬂuence and contrasting landscape characteristics. In the context of northern catchments the sites have exceptionally long and rich data sets of hydrometric data and – most importantly – stable water isotopes for both rain and snow conditions. To adapt the STARR model for sites with strong snow inﬂuence, we used a novel parsimonious calculation scheme that takes into account the isotopic fractionation through snow sublimation and snowmelt. The
Why Imaginary Worlds? The psychological foundations and cultural evolution of fictions with imaginary worlds

Short abstract: Why do fiction makers spend much time and money inventing imaginary worlds? Why are fictions with such imaginary worlds so successful? Current views in cultural evolution do not explain this massive cultural phenomenon. We argue that imaginary worlds tap into exploratory preferences which have evolved in a wide range of species to propel individuals toward new environments. After reviewing research on exploratory behaviors and preferences
UvA-DARE (Digital Academic Repository) Higher-order-structure analysis of proteins by native size-based separations coupled to optical and mass-spectrometric detectors

proteins, and we discuss the existing techniques that serve this purpose. The basic principles of the techniques are briefly explained. Gaps in the technology and challenges related to the characterization of protein HOS are also discussed, shedding light on the high demand for continuous advances in characterization techniques. To demonstrate the suitability of SEC and AF4 coupled with either MALS or nMS for the analysis and characterization of protein HOS and aggregates, applications and findings presented in literature are evaluated.
Department of Land Economy Environment, Law & Economics

39 Coastal land reclamation has been practiced widely to accommodate rapid economic growth and 40 urbanization. However, the exploitation of coastal wetlands also imposes ecological risks and jeopardizes 41 ecological security in many countries. There is a need to assess the overall effects of coastal reclamation. 42 We developed a conceptual framework to assess the ecological impacts of coastal land reclamation in 43 three dimensions: land quantity, ecological environment, and land quality. An integrated index system 44 was constructed accordingly and tested by using data from Cixi, a coastal city in eastern China. Our 45 index system generated rich information to assess the impacts of reclamation on added land area, 46 landscape ecological risk, and cropland soil quality. The results showed that coastal reclamation played 47 an important role in maintaining the balance of the supply and demand of land resources during 48 urbanization in the study area. However, its adverse ecological effects were also evidenced. Coastal 49 reclamation not only increased the landscape disturbance and ecological risk but also significantly 50 decreased the overall cropland soil quality. The city’s original reclamation-driven development strategy 51 is unable to meet the updated requirements of “quantity-quality-ecological balance” for cropland 52 protection. Our index system can help land use policymakers monitor the ecological effects of coastal 53 reclamation. The knowledge gained has major policy implications for sustainable land use management 54 in coastal areas. 55
Mode of growth and life-history strategies of a Late Ordovician halysitid coral

The upper surface of the corallum of Catenipora rubra was often at or just above the sediment-water interface during life. The vertical growth rate was barely sufficient to keep pace with background sedimentation and possible subsidence of the corallum. Therefore, the colonies were in constant danger of being covered by influxes of sediment, especially during storms. This was compensated by the ability of polyps to respond to sedimentation events and by certain aspects of colony growth. Rapid regeneration following partial mortality involved budding of uninjured polyps and rejuvenation of damaged individuals, in some cases accompanied by a type of axial increase not previously known in tabulate corals. Rapid lateral expansion was possible because small, “immature” polyps could bud and grow in a reptant manner. Interconnected ranks of the cateniform corallum served to dam shifting sediment at the periphery of the colony. Lacunae within the colony were reservoirs for material that breached peripheral ranks and for sediment that settled on the ranks and was rejected by polyps or removed by passive flow. Polyps comprising the colony were distributed over a large area of the substrate surface, thereby decreasing the probability of complete mortality during sedimentation events and increasing the probability that a sufficient number of individuals would survive to ensure optimum regeneration. The corallum, anchored in the substrate and with sediment filling the lacunae, provided a broad, stable base during high-energy events. It remains to be established how widespread these growth patterns and strategies were among other corals with cateniform colonies, a form that appeared in many unrelated stocks. Most previous workers emphasized physical strength when considering functional morphology, following a tacit assumption that the corallum rose high above the substrate and was therefore susceptible to breakage during high-energy events. An understanding of the origin of cateniform patterns and the phylogeny of these corals requires knowledge of their modes of growth and life-history strategies, which were genetically as well as environmentally controlled.
Tidal Decay and Stable Roche-Lobe Overflow of Short-Period Tidal Decay and Stable Roche-Lobe Overflow of Short-Period Gaseous Exoplanets Gaseous Exoplanets

Many gaseous exoplanets in short-period orbits are on the verge or are in the process of Roche-lobe overﬂow (RLO). Moreover, orbital stability analysis shows tides can drive many hot Jupiters to spiral inevitably toward their host stars. Thus, the coupled processes of orbital evolution and RLO likely shape the observed distribution of close-in exoplanets and may even be responsible for producing some of the short-period rocky planets. However, the exact outcome for an overﬂowing planet depends on its internal response to mass loss, and the accompanying orbital evolution can act to enhance or inhibit RLO. In this study, we apply the fully-featured and robust Modules for Experiments in Stellar Astrophysics (MESA) suite to model RLO of short-period gaseous planets. We show that, although the detailed evolution may depend on several properties of the planetary system, it is largely determined by the core mass of the overﬂowing gas giant. In particular, we ﬁnd that the orbital expansion that accompanies RLO often stops and reverses at a speciﬁc maximum period that depends on the core mass. We suggest that RLO may often strand the remnant of a gas giant near this orbital period, which provides an observational prediction that can corroborate the hypothesis that short-period gas giants undergo RLO. We conduct a preliminary comparison of this prediction to the observed population of small, short-period planets and ﬁnd some planets in orbits that may be consistent with this picture. To the extent that we can establish some short-period planets are indeed the remnants of gas giants, that population can elucidate the properties of gas giant cores, the properties of which remain largely unconstrained.
Journal of Socioeconomics and Development

The utilization of wetland areas poses a threat to the wetland ecosystems’s vitality. The Kayan Sembakung Delta in North Kalimantan Province is one of the wetland ecosystems that is widely used by humans for various activities, raising concenrs about its sustainability. This study aims to assess the area’s carrying capacity and environmental capacity as well as the level of welfare of small farmers. The research was conducted in March-June 2020 in Tanjung Buka Village, Tanjung Palas Tengah District, Bulungan Regency, which is part of the Kayan Sembakung Delta area. The study employed an analysis of the carrying capacity of the environment as well as an analysis of the poverty and welfare assessment of farmer households using the Nested Sphere of Poverty (NESP) approach. The results showed that Tanjung Buka Village has an area with a high carrying capacity and environmental capacity as a food provider covering an area of 61,352.12 ha. Small farmers experience subjective and objective welfare in the moderate category. Increasing the welfare of small-scale farmers can be done through efforts such as repairing houses below proper standards, meeting food needs, increasing consumption of protein (meat, eggs, fish), providing clean water, diversifying income sources, ease of access to food. sources of employment, promoting conservation of wood and plant species, securing land tenure, complying with local regulations, and improving infrastructure.