Miracle-dz/UniFAR-FTUs huggingface dataset:
Humoral and Cellular Immunity following Five Doses of COVID-19 Vaccines in Solid Organ Transplant Recipients: A Systematic Review and Meta-Analysis

Solid organ transplant (SOT) recipients are at increased risk of COVID-19 infection because of their suppressed immunity. The available data show that COVID-19 vaccines are less effective in SOT recipients. We aimed to assess the cellular and humoral immunogenicity with an increasing the number of doses of COVID-19 vaccines in SOT recipients and to identify factors affecting vaccine response in this population. A systematic review and meta-analysis were conducted to identify ongoing and completed studies of humoral and cellular immunity following COVID-19 vaccines in SOT recipients. The search retrieved 278 results with 45 duplicates, and 43 records did not match the inclusion criteria. After title and abstract screening, we retained 189 records, and 135 records were excluded. The reasons for exclusion involved studies with immunocompromised patients (non-transplant recipients), dialysis patients, and individuals who had already recovered from SARS-CoV-2 infection. After full-text reading, 55 observational studies and randomized clinical trials (RCTs) were included. The proportion of responders appeared higher after the third, fourth, and fifth doses. The risk factors for non-response included older age and the use of mycophenolate mofetil, corticosteroids, and other immunosuppressants. This systematic review and meta-analysis demonstrates the immunogenicity following different doses of COVID-19 vaccines among SOT patients. Due to the low immunogenicity of vaccines, additional strategies to improve vaccine response may be necessary.
Doctorate in Educational and Child Psychology

Children with Social, Emotional and Mental Health (SEMH) needs are more likely to have lower academic and wellbeing outcomes. This often continues into their adult life effecting their opportunities and relationships. Educational psychologist, Marjorie Boxall, developed the Nurture Groups (NGs) intervention to improve the wellbeing of children who presented with challenging behaviour due to their early experiences. NGs utilised an understanding of attachment theory and Maslow’s (1970) hierarchy of needs, to create a space within school where positive attachments could be fostered. In this review, the effectiveness of NGs will be evaluated through studies published following Hughes and Schlosser’s (2014) review. Six papers were included based on their criteria, one of which addressed the secondary review question of the successful strategies used in NG. Further evidence of the effectiveness of NGs at reducing SEMH needs in children was found. However, the need for further studies that include control groups and sample sizes that fulfil the power calculations is discussed.
Compositional generalization in Neuro-Symbolic Visual Question Answering

Compositional generalization is a key challenge in artificial intelligence. This paper investigates compositional generalization capabilities in multimodal mathematical reasoning problems. We introduce compositional generalization splits for CLEVR-Math for reasoning hop-and attribute generalization, testing both systematicity and productivity. We evaluate the NS-VQA architecture and compare it to two neural baselines, ViLT and CLIP. Our results show that none of the models generalize to longer reasoning chains than trained on, while showing similar patterns on fewer hops. For our compositional generalization split, ViLT and the CLIP-based model performs better then NS-VQA on the objects held out during training. However, all models see a significant drop in performance. For length generalization, we propose that explicitly learning recursive definitions can be important for compositional generalization. We discuss how knowledge-based curriculum learning can help future architectures achieve such capabilities.
Smoking and the Business Cycle: Evidence from Germany

In this paper, we use data from the German Socio-Economic Panel to investigate the effect on cigarette consumption of macro-economic conditions in the form of regional unemployment rates. The results from our panel data models, several of which control for selection bias, indicate that the propensity to become a smoker increases significantly during an economic downturn, with an approximately 0.7 percentage point increase for each one percentage point rise in the unemployment rate. Conversely, conditional on the individual being a smoker, cigarette consumption decreases during recessions, with a one percentage point increase in the regional unemployment rate leading to an up to 0.8 percent decrease in consumption.
University of Southern Denmark Sex-specific actuarial and reproductive senescence in zoo-housed tiger (Panthera tigris)

This is the author manuscript accepted for publication and undergone full peer review but has not been through the copyediting, typesetting, pagination and proofreading process, which may lead to differences between this version and the Version of Record. Please cite this article as doi: 10.1002/zoo.21610. This article is protected by copyright. All rights reserved. A ut ho r M an us cr ip t A fifth of all known species are currently classified as threatened in the wild: the rate of biodiversity loss is rapid, continuous, and mostly due to anthropogenic activities. To slow down this decline, the accurate estimation of demographic parameters for threatened species is critical. With this aim, zoo institutions play an important role, giving access to data on zoohoused animals, which aids researchers working on species life-history traits and intrinsic factors influencing the fitness of both sexes, such as age. While tigers (Panthera tigris) are particularly threatened in their natural environment, few of their demographic parameters have been determined because of their solitary and elusive nature as well as low population density. Using individual-based information for more than 9,200 tigers (from 1938 to 2018) recorded in the International Tiger Studbook 2018, we aimed to determine sub-species and sex-specific variability of survival and reproductive parameters with age. No significant sexdifference in actuarial senescence (i.e. decline of survival probabilities with age) was observed but males tended to have a higher juvenile mortality and a faster senescence than females. Reproductive senescence (i.e. decline of reproductive parameters with age) was more pronounced in females than males. Moreover, we observed sub-species-specific variation in mortality and reproductive patterns, pointing out the necessity to consider them independently for conservation goals. Our findings can provide meaningful improvements to the husbandry of zoo-housed tigers, emphasizing the importance of adult breeding females of 7-9 years-old to control zoo-housed population size, but also providing accurate demographic estimates, crucial to set up effective conservation plans.
Technology Adoption and Usage Behaviors in Field Incident Management System Utilization

This study utilized the Unified Theory of Acceptance and Use of Technology (UTAUT) model to analyze the adoption and utilization of field incident management system (IMS) in a manufacturing organization. The study specifically focused on the role of behavior as a key factor in the adoption and utilization of incident management system. Data was collected through a survey of employees who had utilized the IMS system and the UTAUT model was used to analyze the data. The results indicated that behavior in the system significantly influenced the adoption and utilization of IMS. The study also found that the UTAUT model provided a useful framework for understanding the adoption and utilization of IMS, particularly the importance of performance expectancy, effort expectancy, social influence, and facilitating conditions. The study provides valuable insights for organizations looking to implement IMS and improve their incident management processes. It highlights the importance of building behavior in the system through appropriate user experience and user training. The findings of this study have important implications for manufacturing organizations seeking to enhance their incident management procedures through the adoption and utilization of IMS. Keywords—UTAUT; field incident management system (FIMS); regression analysis; user intention and acceptance; system adoption; usage behavior; manufacturing; IMS; effort expectancy; performance expectancy; social influence; facilitating conditions; behavioral intention; ANOVA
An Online Model-Free Adaptive Tracking Controller for Cable-Driven Medical Continuum Manipulators

Continuum manipulators have demonstrated promising potential for flexible access and complicated operation and thus have been emerging and introduced in robot-assisted flexible endoscopy. However, due to their inherent structural compliance and strong nonlinearities, developing an accurate and robust control framework remains challenging. This paper proposes a model-free control method based on the Model-Free Adaptive Control (MFAC) algorithm to accomplish the trajectory tracking for two kinds of continuum manipulators by solely utilizing the robotic system’s real-time input/output data. The presented controller discretizes and dynamically linearizes the motion process of the continuum actuator to obtain a dynamic linearization data (DLD) model. This DLD model can be derived from a pseudo-partial derivative (PPD) matrix updated based on the I/O measurement data for the iterative operation. The stability of the presented MFAC controller can be mathematically guaranteed in theory to provide generality, and the control framework demonstrates a low computational cost and real-time control capability. The superior performance of the presented controller is firstly validated in MATLAB simulations and then compared with the other two controllers. Through experimental validation on two kinds of continuum manipulators, the model-free control framework shows high tracking accuracy and good robustness against the system uncertainty and external disturbances, as well as high transferability.
Making sense of changes in military partners’ post-deployment adjustment concern: Turning points, trajectories, and accounts

Reintegration after a military service member returns home from deployment is a time of uncertainty that requires adjustment by all family members. Building on accounts (i.e., story-like constructions that help make sense of stressful events) scholarship, this study documents (a) turning points (TPs) and (b) patterns in partners’ levels of concern about post-deployment adjustment and investigates (c) how romantic partners account for why changes in adjustment concern occurred. Findings from interviews with 26 military partners reveal that accounts (a) involve multifaceted explanations spanning many domains of life, (b) explain why certain TPs increased and/or decreased concern, and (c) engage the meaning of time in varied ways. The importance of integrating an account-making framework with the TP methodology, theoretical implications for relational turbulence theory, and practical suggestions are discussed.
Knowledge Management as a New Strategy of Innovative Development

Theoretical framework: The relevance of studying the growing role of knowledge management in the context of ensuring the innovative activity of enterprises is increasing. The results demonstrate a number of important conclusions that have made it possible to expand the existing theoretical and practical aspects of the knowledge management concept. Design/methodology/approach: The conducted study in service companies has revealed a low culture of using this concept in the Ukrainian context. In the course of the research, it has been established similar and different features of the influence of knowledge management on innovation of service companies, direct and indirect relationship between variables, complex structure and indirect impact of production, integration, application of information on the speed, quality and number of innovations in enterprises. Findings: The complex structure of the relationship between knowledge and innovative activity can be a consequence of insufficient level of personnel competencies, available information and data management technologies, methods and practices of production, integration and application. Therefore, the low innovativeness of the service companies under study in the context of system orientation and technological capabilities of the companies, in particular, in the practice of knowledge management, and the low impact of knowledge and information on the innovation of services and processes on the market of Ukraine have been revealed. Research, Practical & Social implications: This is precisely why the strategy of personalization significantly prevails in its use in knowledge management compared to the codification strategy, which is manifested in the limited practice of using systems and technologies for the generation, accumulation, storage, use, dissemination of knowledge. Originality/value: In addition, the use of the personalization strategy is explained by the fact that the service companies under consideration focus more on processes, the optimization of which significantly affects interaction with customers and the efficiency of operations.
Evaluating the utility of daily speech assessments for monitoring depression symptoms

Objective Depression is a common mental health disorder and a major public health concern, significantly interfering with the lives of those affected. The complex clinical presentation of depression complicates symptom assessments. Day-to-day fluctuations of depression symptoms within an individual bring an additional barrier, since infrequent testing may not reveal symptom fluctuation. Digital measures such as speech can facilitate daily objective symptom evaluation. Here, we evaluated the effectiveness of daily speech assessment in characterizing speech fluctuations in the context of depression symptoms, which can be completed remotely, at a low cost and with relatively low administrative resources. Methods Community volunteers (N = 16) completed a daily speech assessment, using the Winterlight Speech App, and Patient Health Questionnaire-9 (PHQ-9) for 30 consecutive business days. We calculated 230 acoustic and 290 linguistic features from individual's speech and investigated their relationship to depression symptoms at the intra-individual level through repeated measures analyses. Results We observed that depression symptoms were linked to linguistic features, such as less frequent use of dominant and positive words. Greater depression symptomatology was also significantly correlated with acoustic features: reduced variability in speech intensity and increased jitter. Conclusions Our findings support the feasibility of using acoustic and linguistic features as a measure of depression symptoms and propose daily speech assessment as a tool for better characterization of symptom fluctuations.
Environmental Value Assessment of Plastic Pollution Control: A Study Based on Evidence from a Survey in China

A scientific environmental management decision is based on the correct assessment of environmental value. Aiming to objectively and accurately assess the environmental value of plastic pollution treatment, in this paper, we design a choice experiment with four item characteristic attributes consisting of source reduction, recycling, cleanup and remediation and price. With the research data of 450 interviewed residents, a choice experiment method (CEM) and numerical simulation were used to comprehensively assess the environmental value of plastic pollution treatment in China, incorporating discount rates and future price changes of environmental products into the study. The results showed that: (1) residents’ willingness to pay per capita for source reduction, remediation and recycling was CNY 32.79, CNY 25.27 and CNY 15.78, respectively; (2) from the perspective of compensation surplus, the residents were willing to pay CNY 147.68 per capita for environmental improvement; (3) the dynamic curve of the value of plastic pollution control displayed an increasing, then gradually declining trend, and its total economic value of 100a was CNY 21,259.97 per capita; and (4) the model simulated the possible trajectory of future changes in plastic pollution control (three scenarios of constant, decreasing and increasing rates of development of plastic pollution control services) and found that addressing the plastic pollution problem early is more conducive to improving the overall welfare of society. This study can provide a basis for scientific evaluation of the benefits of plastic pollution management and allocation of pollution management resources.
Detecting Fraudulent Erasures at an Aggregate Level

Wollack, Cohen, and Eckerly suggested the “erasure detection index” (EDI) to detect fraudulent erasures for individual examinees. Wollack and Eckerly extended the EDI to detect fraudulent erasures at the group level. The EDI at the group level was found to be slightly conservative. This article suggests two modifications of the EDI for the group level. The asymptotic null distribution of the two modified indices is proved to be the standard normal distribution. In a simulation study, the modified indices are shown to have Type I error rates close to the nominal level and larger power than the index of Wollack and Eckerly. A real data example is also included.
Prevalence of Antimicrobial Resistance of <i>ESKAPE</i> Pathogens before and during Pandemic COVID-19 Pandemic in a University Affiliated Hospital in Tangerang, Indonesia

Introduction: Antimicrobial resistance is the most important health problems currently. Antibiotic prophylaxis to prevent bacterial co-infections in hospitalized COVID-19 patients, and lack of surveillance were associated with antimicrobial resistance. ESKAPE pathogens consisting of E. faecium, S. aureus, K. pneumoniae, A. baumanii, P. aeruginosa and Enterobacter spp. are associated with healthcare-associated infections. Patients and Methods: This descriptive, retrospective, longitudinal study aims to describe the resistance rates of bloodstream infection due to ESKAPE pathogens from patients admitted in Siloam Hospital Karawaci, before and during COVID-19 pandemic (January 1 st , 2019 until December 31 st , 2022). Out of 296 ESKAPE pathogens collected from blood samples, S. aureus was the most frequent species, followed by K. pneumoniae, A. baumannii, P. aeruginosa, Enterobacter spp. , and E. faecium. Results: Resistance rates of E. faecium were alarmingly high from 2019 until 2021, but in 2022 no sample was found. Resistance rates of S.
Metabolic “Sense Relay” in Stem Cells: A Short But Impactful Life of PAS Kinase Balancing Stem Cell Fates

Tissue regeneration is a complex molecular and biochemical symphony. Signaling pathways establish the rhythmic proliferation and differentiation cadence of participating cells to repair the damaged tissues and repopulate the tissue-resident stem cells. Sensory proteins form a critical bridge between the environment and cellular response machinery, enabling precise spatiotemporal control of stem cell fate. Of many sensory modules found in proteins from prokaryotes to mammals, Per-Arnt-Sim (PAS) domains are one of the most ancient and found in the most diverse physiological context. In metazoa, PAS domains are found in many transcription factors and ion channels; however, PAS domain-containing Kinase (PASK) is the only metazoan kinase where the PAS sensory domain is connected to a signaling kinase domain. PASK is predominantly expressed in undifferentiated, self-renewing embryonic and adult stem cells, and its expression is rapidly lost upon differentiation, resulting in its nearly complete absence from the adult mammalian tissues. Thus, PASK is expressed within a narrow but critical temporal window when stem cell fate is established. In this review, we discuss the emerging insight into the sensory and signaling functions of PASK as an integrator of metabolic and nutrient signaling information that serves to balance self-renewal and differentiation programs during mammalian tissue regeneration.
The Study of the Failure Envelopes of Hollow Shaft Single-Plate Helical Piles in Clay

Helical piles are utilized worldwide as foundations for onshore infrastructure, providing fast installation and high capacity. Their unique advantages have led to their potential as an alternative to monopile foundations for offshore wind turbines. One challenge in their service life is dealing with combined loading caused by wind, waves, current, and the weight of the structure itself. While research has focused on helical piles’ capacity for uniaxial tensile loads, there is limited knowledge regarding their performance under combined loads. This study used FEM analysis to investigate the impact of aspects such as helix-to-shaft diameter ratios and helix position on the capacity and failure mechanisms of hollow shaft single-plate helical piles in clay. With 561 analysis cases under both uniaxial and combined loading, failure envelopes were evaluated for various helix-to-shaft diameter ratios and positions. The study revealed a linear positive correlation between helix-to-shaft diameter aspect ratios and load-bearing ability, while the effect of helix positioning on failure envelopes was more complex and nonlinear. The outcomes from this comprehensive analysis enabled the development of a formula to predict the bearing capacity of helical anchors under combined loading.
Multi-Gravity: Can You Have Too Much of A Good Thing?

The ongoing quest to map the space of possible, consistent field theories, and to determine their properties, is extremely interesting from a purely theoretical perspective, as well as being a prerequisite for the phenomenological application of any such theories. To that end, this thesis is concerned with various theoretical aspects of multi-gravity theories—that is, theories which contain multiple, interacting spin-2 fields. The analysis presented here will proceed by using the Stueckelberg trick to reintroduce the multiple copies of diffeomorphism invariance which the theory would possess if none of the spin-2 fields interacted, and it is discussed in detail how to apply this to multi-gravity, and in particular how this differs from massive and bi-gravity. The structure of the interactions which arise from the helicity-0 modes of the massive gravitons is examined in the so-called decoupling limit. It is found that the structure these take in bi-gravity is generalised to that of multi-Galileons, although this is not always manifest; an extension of the so-called Galileon duality is used to probe this. Multi-gravity theories can be elegantly described using graphs to encode the network of interactions between the different fields, and this forms the basis for the other two questions which will be covered. When the theory contains a cycle of interactions, it is explicitly shown how this leads to the introduction of a ghost-like instability which is not present otherwise, and how this lowers the cutoff of the effective theory. In the absence of cycles, the structural properties of the graph which represents a given theory continue to play a large role in determining the scale at which the effective theory breaks down. This is the final topic, which is studied in detail, and upper and lower bounds on this scale are derived which depend on various properties of the graph.