Miracle-dz/UniFAR-FTUs huggingface dataset:
The preliminary results of physiotherapy scoliosis-specific exercises on spine joint position sense in adolescent idiopathic scoliosis: A randomized controlled trial

Background: It has been observed that there are difficulties in maintaining spinal harmony in the absence of proprioceptive information, which has an important role in achieving postural control in scoliosis. One of the tests used to evaluate proprioceptive mechanisms is joint position reproduction. Objective(s): The main aim of our study was to investigate the effect of physiotherapy scoliosis-specific exercise (PSSE) on spine joint reposition (JR) sense. The second aim was to determine the effects of PSSE on the angle of trunk rotation (ATR), posture, and deformity perception in adolescent idiopathic scoliosis. Methods: Twenty-nine patients with adolescent idiopathic scoliosis (mean age 13.79 ± 1.82 years) were randomly allocated to two groups. “Schroth” exercises were applied to the PSSE group for 8 weeks (16 sessions). The control group was placed on the waiting list. Patients' JR error (dual inclinometer), ATR (scoliometer), posture parameters (PostureScreen Mobile, Posterior Trunk Asymmetry Index, and Anterior Trunk Asymmetry Index), and deformity perception (Walter Reed Visual Assessment Scale [WRVAS]) were assessed at the first session and at the end of 8 weeks. Results: The initial demographic characteristics, Cobb (thoracal: 19.41 ± 7.03 degrees; lumbar: 20.76 ± 7.24 degrees) and ATR (thoracal: 5.86 ± 3.98 degrees; lumbar: 5.66 ± 3.33 degrees) and clinical test parameters of the groups (JR, posture parameters, and WRVAS) were similar (P > .05). According to the findings, thoracal and lumbar JR error values (P < .05), ATR (P ≤ .001), posture parameters (P ≤ .001), and WRVAS (P = .048) were significantly improved in the PSSE group. Besides, when the groups were compared, a significant difference was found in favor of PSSE except for the deformity perception (P < .05). Conclusions: Schroth exercises have a positive contribution for improving JR sense of the spine, vertebral rotation, and posture.
Neural Correlates of Dual-Task Processing following Motor Sequence Learning: A Functional Near-Infrared Spectroscopy (fNIRS) Study

Abstract The current study used functional near-infrared spectroscopy (fNIRS) to examine cerebral oxygenation changes in the prefrontal cortex (PFC) associated with dual-task processing before and after motor sequence learning. Participants performed self-initiated sequential finger movements that were 4 and 12 units in length with a visual letter-counting task. After practice, dual-task sequence-4 performance revealed decreased activity in the right dorsolateral PFC, medial PFC, and orbitofrontal cortex. However, dual-task sequence-12 performance revealed increased activity in the right ventrolateral PFC when compared to the left hemisphere. The findings suggest that dual-task interference was reduced following practice for dual-task sequence-4. The results also suggest that increased right hemisphere activation is needed to maintain performance when the primary sequential task (e.g., dual-task sequence-12) has a high level of difficulty.
Intimate Partner Violence and Unmet Need for Family Planning in Selected South Asian Countries

This article analyzes the relationship between various forms of intimate partner violence (IPV) and unmet need for family planning (FP) in South Asia. The data were obtained from the latest wave of the Demographic and Health Survey in Afghanistan, India, Maldives, Nepal, and Pakistan. Binary logistic regression analyses show mixed results, with a significant association between at least one type of IPV and unmet need for FP in all countries under study, except Maldives. There were also contrasting findings on the IPV–unmet need nexus, with a positive sign in some but negative sign in others. Women who experienced physical violence were associated with a higher odds of having an unmet need in Pakistan, but the opposite was true in Afghanistan and Nepal. The odds of having an unmet need were higher among Indian women who experienced IPV (sexual and emotional). In Afghanistan, women who experienced IPV (physical and emotional) have lower odds of having an unmet need. However, the interaction analysis of IPV (physical and sexual) and partners’ controlling behavior showed a positive association with unmet need. Policymakers need to develop policies and strategies to prevent IPV and reduce unmet need for FP, in line with the Sustainable Development Goals.
Fathers’ level of involvement in childcare activities and its association with the diet quality of children in Northern Ghana

Abstract Objective: This study assessed the level of fathers’ involvement in childcare activities and its association with the diet quality of their children in Northern Ghana. Setting: The study was carried out in the Northern, Upper East and Upper West regions of Ghana. The people in the study area mostly depend on agriculture as their main occupation. Design: A community-based comparative analytical cross-sectional study. Participants: A sample of 422 rural mother–father pairs who had at least one child aged 6–36 months. Results: The overall level of fathers’ involvement in childcare and feeding activities was high among 63·5 % of the respondents in the 6 months prior to the study. The most common childcare activity men were involved in was providing money for the purchase of food for the child. Minimum acceptable diet was higher for children with a higher level of paternal involvement in childcare activities (adjusted OR = 3·33 (95 % CI: 1·41, 7·90)), compared to their counterparts whose father’s involvement was poor. Fathers who had a positive attitude to childcare and feeding were 2·9 more likely to get involved in childcare activities (adjusted OR = 2·90 (95 % CI: 1·87, 4·48)). Conclusions: The findings confirm earlier studies that show that fathers’ involvement in childcare activities including feeding is positively associated with improved child feeding practices. The findings point to the need to have a policy shift in which both men and women are key actors in interventions designed to improve child nutritional status in rural settings of Northern Ghana.
On an extended RYTOV approximation and its comparison with the born approximation

In remote sensing problems for continuous inhomogeneous media, the Born approximation is used conveniently for tenuous, slowly changing media. The Rytov approximation is known, under certain circumstances, to give more accurate indication than the Born approximation, we have introduced an improvement that further increases the range of validity of the Rytov approximation. Some numerical results are presented to illustrate the advantages of the method introduced over that of Born and Rytov.
Long-term outcomes for patients with Hodgkin lymphoma at increased risk of progression or relapse

Abstract Although advancements in the treatment of Hodgkin lymphoma have enabled many patients to be cured of their disease, about half of patients who relapse or experience refractory disease ultimately fail treatment, even after autologous stem cell transplant. Risk stratification is crucial to enable escalation of therapy in patients at increased risk for progression while allowing for less intensive therapy in lower risk groups. Utilization of clinical factors to inform risk scores was common practice, but this historical approach has been supplemented by PET/CT risk adapted management. Long-term outcomes of high-risk patients have improved over the decades with advancements in therapy and emergence of novel agents including antibody-drug conjugates and immune checkpoint inhibitors, yet further research is urgently needed. Herein, we review long-term outcomes of patients with Hodgkin lymphoma at increased risk for progression or relapse and discuss limitations of current risk strategies.
Radical groups of finite abelian subgroup rank

Following Plotkin we term a group radical, if each of its non-trivial epimorphic images possesses a non-trivial locally nilpotent normal subgroup. A group has been termed offinite abelian subgroup rank, if its elementary abelian primary subgroups are finite and if its torsionfree abelian subgroups are of finite rank. For the sake of brevity and for the moment we term 9-group every radical group of finite abelian subgroup rank. Subgroups and epimorphic images of 9-groups are 9-groups; and extensions of 9-groups by 9-groups are 9-groups [Discussion of Theorem 6.1, (/k)]. 9-groups are countable; and every epimorphic image, not 1, of an 9-group possesses an abelian characteristic subgroup, not 1, which is either finite, elementary and primary or torsion-free of finite rank [Theorem 6.1, (a)]. The intersection of all subgroups of finite index in an 9-group is a nilpotent characteristic subgroup without proper subgroups of finite index [Theorem 6.1, (b)]. If an 9-group is a torsion group, then it is locally finite-soluble and its Sylow subgroups of equal characteristic are conjugate; it is an extension of a radicable abelian group by a residually finite group [Theorem 6.1, (c) Proposition 4.5]. If 1 is the only normal torsion subgroup of an -group, then it is soluble of finite rank and its torsion subgroups are finite of bounded order; it is an extension of a torsion free nilpotent group by a no.etherian and almost abelian group [Theorem 6.1, (d) W Proposition 5.5]. It is easy to construct abelian groups of finite abelian subgroup rank which are not of finite rank [in the sense of Prtifer]; and 9-groups need not be soluble [Discussion of Theorem 6.3, (A) ]. The 9-groups of finite rank are then characterized by the following equivalent properties: A group is a radical group whose abelian subgroups are of finite rank if, and only if, it is of finite rank and an extension of a hypercentral torsion group whose primary components are artinian and almost abelian by a soluble group [Theorem 6.3]. More especially we show that a group G is soluble of finite rank and the number of primes which are orders of elements in G is finite if, and only if, G is radical and its elementary abelian and torsion free abelian subgroups are of finite rank [Theorem 7.1]. It is noteworthy that a group G possesses an 9-subgroup of finite index if, and only if, G is of finite abelian subgroup rank and its infinite epimorphic images possess normal subgroups, not 1, which are finite or radical [Theorem 8.1].
Hip Fracture-Related Emergency Department Visits, Hospitalizations and Deaths by Mechanism of Injury among Adults Aged 65 and Older, United States 2019

Objective Describe rates of hip fracture-related emergency department (ED) visits, hospitalizations, and deaths among older adults (aged ≥65 years) in the United States. Methods Data from the 2019 Healthcare Cost and Utilization Project and National Vital Statistics System were used to calculate rates of hip fracture-related ED visits, hospitalizations, and deaths among older adults by select characteristics and mechanism of injury. Results In 2019, there were 318,797 ED visits, 290,130 hospitalizations, and 7731 deaths related to hip fractures among older adults. About 88% of ED visits and hospitalizations and approximately 83% of deaths related to hip fractures were caused by falls. Rates were highest among older adults living in rural areas and among those aged ≥85 years. Discussion Most hip fractures among older adults are fall-related. Healthcare providers can prevent falls among their older patients by screening for fall risk, assessing modifiable risk factors, and offering evidence-based interventions.
Contrasting transcriptomic patterns reveal a genomic basis for drought resilience in the relict fir Abies pinsapo Boiss.

Climate change challenges the adaptive capacity of several forest tree species in the face of increasing drought and rising temperatures. Therefore, understanding the mechanistic connections between genetic diversity and drought resilience is highly valuable for conserving drought-sensitive forests. Nonetheless, the post-drought recovery in trees from a transcriptomic perspective has not yet been studied by comparing contrasting phenotypes. Here, experimental drought treatments, gas-exchange dynamics, and transcriptomic analysis (RNA-seq) were performed in the relict and drought-sensitive fir Abies pinsapo to identify gene expression differences over immediate (24 hours) and extended drought (20 days). Post-drought responses were investigated to define resilient and sensitive phenotypes. Single nucleotide polymorphisms (SNPs) were also studied to characterize the genomic basis of A. pinsapo drought resilience. Weighted gene co-expression network analysis showed an activation of stomatal closing and an inhibition of plant growth-related genes during the immediate drought, consistent with an isohydric dynamic. During the extended drought, transcription factors, as well as cellular damage and homeostasis protection-related genes prevailed. Resilient individuals activate photosynthesis-related genes and inhibit aerial growth-related genes, suggesting a shifting shoot/root biomass allocation to improve water uptake and whole-plant carbon balance. 152 fixed SNPs were found between resilient and sensitive seedlings, which were mostly located in RNA-activity-related genes, including epigenetic regulation. Contrasting gene expression and SNPs were found between different post-drought resilience phenotypes for the first time in a forest tree, suggesting a transcriptomic and genomic basis for drought resilience. The obtained drought-related transcriptomic profile and drought-resilience candidate genes may guide conservation programs for this threatened tree species.
Diffusive transport in Weyl semimetals

Diffusion, a ubiquitous phenomenon in nature, is a consequence of particle number conservation and locality, in systems with sufficient damping. In this paper we consider diffusive processes in the bulk of Weyl semimetals, which are exotic quantum materials, recently of considerable interest. In order to do this, we first explicitly implement the analytical scheme by which disorder with anisotropic scattering amplitude is incorporated into the diagrammatic response-function formalism for calculating the `diffuson'. The result thus obtained is consistent with transport coefficients evaluated from the Boltzmann transport equation or the renormalized uniform current vertex calculation, as it should be. We thus demonstrate that the computation of the diffusion coefficient should involve the transport lifetime, and not the quasiparticle lifetime. Using this method, we then calculate the density response function in Weyl semimetals and discover an unconventional diffusion process that is significantly slower than conventional diffusion. This gives rise to relaxation processes that exhibit stretched exponential decay, instead of the usual exponential diffusive relaxation. This result is then explained using a model of thermally excited quasiparticles diffusing with diffusion coefficients which are strongly dependent on their energies. We elucidate the roles of the various energy and time scales involved in this novel process and propose an experiment by which this process may be observed.
A Longitudinal Analysis of the Association Between Long-Term Exposure to Air Pollution and Cognitive Function Among Adults Aged 45 and Older in China

Abstract Objectives Evidence suggests long-term exposure to fine particulate matter air pollution (PM2.5) is associated with a higher risk of cognitive impairment, especially among older adults. This study examines the relationship between PM2.5 exposure and cognitive function in China’s aging population. Methods We used longitudinal data from the China Health and Retirement Longitudinal Study (2011–2015) linked with historical PM2.5 concentrations (2000–2015) from remotely sensed satellite data. Growth curve models were applied to estimate associations between PM2.5 exposure (measured in intensity, duration, and a joint variable of intensity with duration for cumulative exposure) and cognitive function. Results Relative to the lowest exposure group, exposure in the second group of PM2.5 intensity (35–50 μg/m3) is associated with poorer cognitive function, but higher levels of PM2.5 appear to be associated with better cognitive function, indicating a U-shaped association. Similar patterns are seen for fully adjusted models of PM2.5 duration: the second group (13–60 months) is associated with worse cognitive function than the first group (0–12 months), but coefficients are nonsignificant in longer duration groups. Joint analysis of PM2.5 intensity with duration suggests that duration may play a more detrimental role in cognitive function than intensity. However, we do not find a statistically significant association between PM2.5 exposure and the rate of cognitive decline. Discussion Our findings are mixed and suggest that some categories of higher and longer exposure to PM2.5 are associated with poorer cognitive function, while that exposures do not hasten cognitive decline. However, more work is necessary to disentangle PM2.5 exposure from individuals’ background characteristics, particularly those jointly associated with cognitive function and urban living.
Low-dose CT noise reduction based on local total variation and improved wavelet residual CNN.

BACKGROUND Low-dose computed tomography (LDCT) is an effective method for reducing radiation exposure. However, reducing radiation dose leads to considerable noise in the reconstructed image that can affect doctor's judgment. OBJECTIVE To solve this problem, this study proposes a local total variation and improved wavelet residual convolutional neural network (LTV-WRCNN) denoising model. METHODS The model first introduces local total variation (LTV) to decompose the LDCT image into cartoon and texture image. Next, the texture image is filtered using the non-local mean (NLM). Then, the cartoon image is added to the filtered texture image to obtain the preprocessing image. Finally, the pre-processed image is fed into the improved wavelet residual neural network (WRCNN) to obtain an improved image. Additionally, we also introduce a compound loss in wavelet domain that combines mean squared error loss and directional regularization loss to separate the structural details from noise more thoroughly. RESULTS Compared with state-of-the-art methods, the peak-signal-to-noise ratio (PSNR) value and the structure similarity (SSIM) value of the processed CT images using the new proposed model are 33.4229 dB and 0.9158. Study also shows that applying new model obtains better results visually and numerically, especially in terms of the preservation of structural details. CONCLUSIONS The proposed new model is feasible and effective in improving the quality of LDCT images.
Achieving and Sustaining Change Through Capacity Building Train-the-Trainer Health Initiatives in Low- and Middle-Income Countries: A Systematic Review

Introduction: Given the anticipated health challenges, forecasted deficiencies in the global health workforce, and steady demands to work through resource constraints, effective and efficient training approaches to build capacity are direly needed. Although train-the-trainer (T3) is not a new approach, there has been considerable interest in using it to develop and sustain capacity, particularly in low- and middle-income countries. This systematic review aimed to better understand the factors to achieve and sustain change across multiple countries and levels through T3 approaches. Methods: A literature search was conducted of six scholarly, peer-reviewed, and gray literature databases. Data were extracted for the study method, design, characteristics, and implicit or explicit factors related to maximizing the likelihood of achieving and sustaining change. An existing conceptual framework for T3 interventions in global health guided the thematic analysis. The framework consisted of five factors pertinent to capacity building T3 initiatives: Talent, Resources, Alignment, Implementation, and Nurture and Development. Results: Twenty-two studies met the inclusion criteria. The T3 training spanned all geographical regions, but interventions were most prevalent in sub-Saharan Africa (46%). Nearly all studies (68%) quantitatively examined change at the individual level (95%), but some studies also explored change at the organizational (77%) and institutional (23%) levels. Implementation and Nurture/Development were the two most salient factors in achieving and sustaining change. The greatest hindrances involved Resources and Context, an additional theme that the data identified. Discussion: The findings and recommendations from this first systematic review exploring antecedents influencing change through health-related T3 interventions can inform training and capacity-building investments, improve existing T3 initiatives, and steer planning for future approaches.
Pseudogene UBE2MP1 derived transcript enhances in vitro cell proliferation and apoptosis resistance of hepatocellular carcinoma cells through miR-145-5p/RGS3 axis

Pseudogenes are barely transcribed at normal, while the anomalous transcripts of them are mostly regarded as long non-coding RNAs (lncRNAs), which play potential functions in human tumorigenicity and development. The exact effects of pseudogene-derived transcripts on hepatocellular carcinoma (HCC) are ambiguous. According to our previous research and constructed database on the HCC-related lncRNAs, we noticed that UBE2MP1 was transcriptionally activated in HCC as a pseudogene from the ubiquitin-conjugating enzyme member UBE2M. In this study, we validated the high expression of the UBE2MP1 transcript in HCC and its adverse correlation with dismal outcomes for the patients. UBE2MP1 depletion at the transcript level significantly impaired cell proliferation and apoptosis resistance in HCC cell lines. Notably, we discovered that the UBE2MP1 transcript shared a specific sequence, binding to the miR-145-5p seed region with a typical ceRNA effect. Simultaneously, we verified an axis of miR-145-5p/RGS3 in HCC cells, which promoted cell proliferation and apoptosis resistance with significance. And modulation of UE2MP1 could remarkably affect RGS3 expression and consequentially influence HCC cell growth in vitro. And combined with the rescue experiment modulating either miR-145-5p or RGS3 furtherly indicated UBE2MP1 as an upstream regulator of the axis in promoting HCC cell growth and maintenance. Thus, our findings provide new strategies for HCC prevention and individual treatment.