Miracle-dz/UniFAR-FTUs huggingface dataset:
A High-Performance, Conflict-Free Memory-Access Architecture for Modular Polynomial Multiplication

In this article, we present the HiCoP architecture, a high-performance, conflict-free memory access, modular polynomial multiplication design that accelerates the number-theoretic transform (NTT), inverse NTT (INTT), and modular polynomial multiplications. To optimize hardware costs, the HiCoP architecture utilizes a high-radix reconfigurable butterfly unit (RBU) that can be dynamically configured to perform NTT, INTT, and point-wise multiplications, alongside an area-efficient Montgomery modular multiplier (MMM) tailored for NTT-friendly modulus. Moreover, by integrating pre-processing, post-processing, and Montgomery domain transformations into NTT and INTT operations, we effectively minimize the cycle count for modular polynomial multiplication. Additionally, we propose a novel conflict-free memory access algorithm that simplifies the control logic and eliminates the need for ping-pong memory in the HiCoP architecture. Experimental results of modular polynomial multiplications demonstrate significant performance gains for the HiCoP architecture implemented on the Xilinx Virtex-7 field-programmable gate array (FPGA) platform, with up to <inline-formula> <tex-math notation="LaTeX">$8.75\times $ </tex-math></inline-formula>, <inline-formula> <tex-math notation="LaTeX">$4.15\times $ </tex-math></inline-formula>, <inline-formula> <tex-math notation="LaTeX">$10.57\times $ </tex-math></inline-formula>, and <inline-formula> <tex-math notation="LaTeX">$8.50\times $ </tex-math></inline-formula> improvements in throughput-to-hardware-cost ratio for LUT count, FF count, BRAM count, and DSP count, respectively.
Play Support Strategies of Preschool Teachers with Different Perspectives on Play and Its Role in Child’s Development

The recognition of play importance does not always lead to the creation of good conditions for its development. An attempt to turn play into classes, to use it for teaching, leads to the disappearance of spontaneous play from kindergartens. There is a gap between the declared pedagogical aim and real practice. This may be due to understanding the key features of play and its role in child’s development. The purpose of the study is to study what criteria teachers use to distinguish between play and a pseudo-play, how the understanding of play is related to the strategy of its support. Structured interviews, including commentary on 2 videos, were conducted with 34 preschool teachers. The assessment of the conditions for play development was carried out using the scale "Play Environmental Rating Scale" in 28 preschool classrooms (13 kindergartens). The average total score is 3,35 (sd=1,31; med=3,43), which corresponds to the minimal quality level of conditions for play. Key deficits are the participation of the teacher in joint play with children, the provision of conditions for multi-age interaction. Significant differences are revealed in the strategy of play support among teachers with a contrasting understanding of the pseudo-play video. Teachers who distinguish between play and pseudo-play and emphasize the developmental value of spontaneous children's play create a multifunctional play environment and more often participate in joint play as partners. Teachers who do not distinguish between a play and a pseudo-play are more often too didactic or outsiders, they create a realistic play environment. The results of the study can be used in elaboration of programs for teacher’s professional development.
CALIBRATION CHAMBER TESTS OF A CONE PENETROMETER IN SAND. DISCUSSION

The discusser, M. Fahey of the University of Western Australia, disscusses the limitation of calibration chamber tests for investigations of in situ testing devices, particularly boundary conditions. Equations for cylindrical cavity expansion are also discussed. Discussers K. Been, D. Horsfield, and M.G. Jefferies of Canada point out that the mean normal stress which effectively makes horizontal stress twice as important as vertical stress, provides a consistently satisfactory normalization for calibration chamber test data. The difficulties in dealing with complex boundary value problems in a purely empirical fashion are noted. This is followed by the author's reply.
Nutrient Intake Status, Existing Problems and Countermeasures of Chinese Residents in the Past 30 Years

: Nutrients are the basic substances to promote human metabolism and maintain health, and their long-term unreasonable intake will increase the risk of chronic diseases among residents. The time series analysis method was used to comprehensively and systematically analyze the nutrient intake status, existing problems and adverse consequences of Chinese residents in the past 30 years. The analysis results show that the structural imbalance of nutrient intake caused by insufficient overall intake of nutrients, excess partial intake of nutrients and uneven overall intake of nutrients is the main problem of nutrient intake of Chinese residents, which is mainly manifested as "two more and four less", that is, more fat intake, more sodium intake, less mineral intake, less water intake, less vitamins intake, and less dietary fiber intake.There is a significant causal relationship between the long-term structural imbalance of nutrient intake and the high incidence of chronic diseases among Chinese residents. Effective measures can be taken to cope with the high incidence of chronic diseases by controlling the quality of nutrients intake, balancing the amount of nutrients intake, developing good daily eating habits, and improving the overall level of public awareness of nutrients.The research results provide a new theoretical perspective and application path for the prevention and treatment of chronic diseases in China, and have important theoretical value and practical significance for promoting the construction of a healthy China.
A Report of a Case of Segmental Zoster Paresis Demonstrated by Limb Paralysis and a Review of the Literature

Varicella zoster virus (VZV) lies dormant in our spinal dorsal root ganglia until reactivation occurs and causes herpes zoster. VZV can spread from the dorsal root to the neighboring ventral root and cause subsequent segmental paresis. In this case report, we present the case of a 78-year-old female who was hospitalized after she developed right upper extremity paresis and altered mental status four days after the eruption of a vesicular rash involving the same dermatome. The patient received intravenous acyclovir, gabapentin, and inpatient rehabilitation. She was found to have made a full recovery one year later. Pain and a vesicular rash is the most common presentation of VZV infection in the elderly. However, segmental zoster paresis should be suspected in any patient with paralysis and a recent diagnosis of herpes zoster.
“We’re Not Proud of the Cases We’ve Been Involved in”: Crisis Resolution on Facebook Using Conversational Human Voice

The article discusses the use of conversational human voice (CHV) to address negative eWOM on brand-generated social media platforms. Using the case of a crisis-ridden Danish bank, the article investigates the use of CHV outside service failures and its effects on critical publics in the context of intentional crises. The data consist of posts and comments from the bank’s Facebook page, following allegations of money laundering. The analysis reveals that CHV is used extensively by the bank to counter criticism; however, the degree to which the strategy is standardized or tailored seems to depend on whether users appear once, have a regular presence, engage in dialog, and are known to the bank’s employees. These findings suggest that while CHV is intended for more personalized communication to make users more sympathetic to the organization, its use will have to be contextualized to be effective.
Diffraction Efficiency of Reflective Metallic Gratings Operating in the THz Range

Far infrared spectrometers have a prominent role to play in future space missions devoted to unveiling the obscure universe. Diffraction gratings are the heart of these instruments that, when operating in the range of a few terahertz, shall cover a wide spectral range providing the highest resolution and efficiency, generally for only a single polarization, within the specified spectral range. This contribution describes the optimization of the diffraction efficiency of the first diffractive order for a blazed metallic grating working at a large angle of incidence. Since the grating period is of the same order of magnitude as the wavelength, it is necessary to approach the design by solving Maxwell's equations rigorously using computational electromagnetism. We have applied the rigorous coupled-wave analysis and the finite element methods to simulate the performance of the grating. This analysis provides relevant hints for the selection of the period, and the blaze and slant angles of the grating. A metallic blazed grating has been fabricated on aluminum and its topography has been characterized to determine the discrepancies with respect to the nominal values. The fabricated profile has been simulated to obtain the expected results in efficiency in comparison with the ideal case. This analysis provides guidance for improved manufacturing processes and experimental verification.
The International Year of Planet Earth in Portugal: Past Activities and Further Developments

The Portuguese National Committee for the IYPE was created in the framework of the Portuguese National Commission for UNESCO, in April 2007. The Committee incorporated the contributions of 220 private and public organizations, mainly municipalities and educational institutions of all levels, and sponsored more than 500 activities since then. The Scientific Programme emphasized relevant cooperation between Earth scientists from the Community of Portuguese Speaking Countries, under the guidance of their National Committees (Angola, Brazil, Cape Verde and Mozambique). In consideration of the community of 230 million Portuguese speaking people, the Portuguese National Committee translated and printed the twelve brochures produced by IUGSUNESCO, posted them on the official website (www.anoplaneta-terra.org), and supported several editions also in Braille, in order to make Earth sciences readily accessible to all citizens. As a result of these accomplishments during the IYPE triennium (2007-2009), the Portuguese National Committee was invited by the UNESCO-IUGS Corporation to co-organize Planet Earth Lisbon '09, the Global Closure Event of the IYPE, which took place in Lisbon, 20 th to 22 nd November 2009.
What I learned by doing craft when I got terminal cancer

In this paper I use theory on craft and psychophysical wellbeing to extract insights on the value and meaning I found in woodcarving after being diagnosed with terminal brain cancer. I continued to carve wood throughout the entire diagnosis and treatment period. I was already an experienced woodcarver and had done extensive research on my own making processes. Both the making and research provided meaning and value for me in my ordeal. I discuss three lessons I learned: 1) Deliberate controlling of attention on the here and now worked as a coping mechanism, giving meaning and value to my situation; 2) Grounding myself in physical touch with a close connection to the material contributed to maintaining my positive identity as both maker and researcher, and acted as another coping resource; and 3) As I made the objects, I re-made myself. My intention to save and finish these artifacts, and the joy I experienced as I finished them, gave meaning and purpose to my situation. These lessons support previous findings on craft and wellbeing, contribute insider insights on the use of wood in art making during cancer treatment, and they could potentially inspire others facing dire straits to use crafting to cope.
Investigating behind the lining of the Tunnel of Eupalinus in Samos (Greece) using ERT and GPR

The 2.5-km-long Eupalinian Aqueduct in the island of Samos, Greece, comprises the most impressive sample of ancient Greek engineering surviving almost intact. The main construction is a tunnel 1036 m long and almost 1.8 m wide excavated from both ends into mainly the massif limestone. In some parts of the overall length of about 240 m, the tunnel is dressed by lining of archaic and Roman age. This is of remarkable quality, and presumably, it protected the parts of the tunnel that were affected by subsidence and cave-ins. At some particular locations, it suffers deformations and other failures. Thus, prior to its restoration and protection measures design, an integrated geophysical survey was carried out on the faces of the supporting walls, consisting in ground-penetrating radar and electrical resistivity tomography works. The survey aimed to investigate the structure at the unseen area behind the lining. The thickness of the lining walls was accurately assessed by the ground-penetrating radar method and proved to be about 0.3 m–0.5 m on average. On the other hand, the width of the excavation behind the walls was predicted and checked at some particular locations with the electrical resistivity tomography works.
Is Coming Out in the Community College Classroom an “Occupational Hazard?”

Objective: This study is a replication of Russ et al.’s (2002) work, which showed that students’ credibility beliefs about and perceived learning from a male university instructor were negatively affected when he identified as gay. Because the primary professional responsibility of community college faculty is teaching, and student evaluations may influence decisions about teacher effectiveness, perceived teacher credibility may be of particular importance within community colleges. Given the number of years that have elapsed since the 2002 study, determining whether the documented bias still exists is necessary. Therefore, the purpose of this study was to determine how community college students’ perceptions of a male teacher’s credibility and perceptions of their own learning were influenced by the instructor being open about his sexual orientation. Methods: This study used mixed methods, was undergirded by Critical Realism, and employed a sequential design with questionnaires and semi-structured interviews. Results: Participants as a collective did not provide significantly different ratings for any dimension of credibility nor for perceptions of learning in either condition. Interview data largely supported the statistical findings; however, they also revealed discomfort with gay instructors and an eagerness to support marginalized instructors; participant reactions aligned with three broad categories of indifference, discomfort, or allyship. Open-ended responses suggested that participants attended more to competence for the straight lecturer and more to character traits for the gay lecturer. Contributions: The findings, especially with regard to participants’ reduced focus of attention on competence for marginalized instructors, have practical implications for equity and faculty evaluation.
Creating effective project-based courses: personal relevance and its relations to successful group work

ABSTRACT Group projects are expected in contemporary engineering curricula, and yet they often pose a challenge to students and instructors alike. Could making projects personally relevant help? The present study created and tested a conceptual framework regarding the impact of personal relevance on groupwork in a project-based learning (PBL) course. We examined how measures of personal relevance (PR), both at the course level (value, interest in specialisation) and specifically regarding projects (interest and investment in the project, and contribution to the project idea) relate to students’ expectancy, group connectedness, team dynamics (effectiveness, conflict, satisfaction, interdependence, and cohesiveness), and perceived effort; whether PR differs based on students’ gender, academic year, or time of the semester; and whether PR predicts students’ project performance. Seventy-one undergraduates in a project-based computer science course at a large public US university completed surveys assessing these constructs at five timepoints during the semester. Our findings suggest PR is related to positive outcomes in PBL courses, with interest and investment predicting an increase in the project grade. Similarly, gender predicted project grade with female students having significantly higher scores overall, above and beyond other measures. We discuss implications for creating project-based courses in higher education engineering courses.
Selective ROCK Inhibitor Enhances Blood Flow Recovery after Hindlimb Ischemia

The impairment in microvascular network formation could delay the restoration of blood flow after acute limb ischemia. A high-content screen of a GSK-published kinase inhibitor library identified a set of ROCK inhibitor hits enhancing endothelial network formation. Subsequent kinase activity profiling against a panel of 224 protein kinases showed that two indazole-based ROCK inhibitor hits exhibited high selectivity for ROCK1 and ROCK2 isoforms compared to other ROCK inhibitors. One of the chemical entities, GSK429286, was selected for follow-up studies. We found that GSK429286 was ten times more potent in enhancing endothelial tube formation than Fasudil, a classic ROCK inhibitor. ROCK1 inhibition by RNAi phenocopied the angiogenic phenotype of the GSK429286 compound. Using an organotypic angiogenesis co-culture assay, we showed that GSK429286 formed a dense vascular network with thicker endothelial tubes. Next, mice received either vehicle or GSK429286 (10 mg/kg i.p.) for seven days after hindlimb ischemia induction. As assessed by laser speckle contrast imaging, GSK429286 potentiated blood flow recovery after ischemia induction. At the histological level, we found that GSK429286 significantly increased the size of new microvessels in the regenerating areas of ischemic muscles compared with vehicle-treated ones. Our findings reveal that selective ROCK inhibitors have in vitro pro-angiogenic properties and therapeutic potential to restore blood flow in limb ischemia.
Real-World Outcomes in Patients with Metastatic Colorectal Cancer in Spain: The RWD-ACROSS Study

Simple Summary Metastatic colorectal cancer is common and complicated to treat. The first choice of treatment is guided by the genetics of the patients (RAS mutation status) and the location of their primary tumor. However, real-world information on what treatments are actually being used and the survival benefits of these patient-guided treatments in Spain is lacking, so we aimed to determine this. We found that, in general, treatment choice was guided by primary tumor location and mutation status, with mutation status being the more influential characteristic. In addition, non-mutated RAS or left-sided tumors were predictive of longer survival times. We hope the results of this study may serve as a useful benchmark for future studies and assist practicing oncologists in selecting appropriate treatments for their patients. Abstract The retrospective, observational RWD-ACROSS study analyzed disease characteristics, systemic treatment, and survival in patients with metastatic colorectal cancer (mCRC) in Spain. In total, 2002 patients were enrolled (mean age 65.3 years; 62.7% male). Overall median overall survival (OS) was 26.72 months, and was longer in patients with left-sided tumors (28.85 vs. 21.04 months (right-sided tumors); p < 0.0001) and in patients receiving first-line anti-epidermal growth factor receptor (EGFR) treatment (31.21 vs. 26.75 (anti-vascular endothelial growth factor (VEGF) treatment) and 24.45 months (chemotherapy); p = 0.002). Overall median progression-free survival (PFS) was 10.72 months and was longer in patients with left-sided tumors (11.24 vs. 9.31 months (right-sided tumors); p < 0.0001), and in patients receiving either first-line anti-EGFR or anti-VEGF (12.13 and 12.00 vs. 8.98 months (chemotherapy); p < 0.001). PFS was longer with anti-VEGF treatment in patients with right-sided tumors and wild-type RAS (11.24 vs. 8.78 (anti-EGFR) and 7.83 months (chemotherapy); p = 0.025). Both anti-EGFR and anti-VEGF produced longer PFS in patients with left-sided tumors and wild-type RAS than chemotherapy alone (12.39 and 13.14 vs. 9.83 months; p = 0.011). In patients with left-sided tumors and mutant RAS, anti-VEGF produced a longer PFS than chemotherapy alone (12.36 vs. 9.34 months; p = 0.001). In Spain, wild-type RAS or left-sided mCRC tumors are predictive of longer survival times.
Antimicrobial resistance patterns of Acinetobacter baumannii and Klebsiella pneumoniae isolated from dogs presented at a veterinary academic hospital in South Africa

Background: Acinetobacter baumannii and Klebsiella pneumoniae are opportunistic bacterial pathogens responsible for hospital-acquired infections in veterinary medicine. Infection with these bacteria always requires urgent antimicrobial therapy. However, there is no evidence of studies that have investigated the antimicrobial drug resistance profile of these organisms in a veterinary setting in South Africa. This study investigated the antimicrobial resistance (AMR) patterns of A. baumannii and K. pneumoniae from clinical specimens obtained from dogs presented at a veterinary academic hospital. The findings of this study contribute to an improved understanding of the AMR profile of these bacteria in veterinary medicine. Materials and Methods: Retrospective data of clinical samples from dogs that were positive for A. baumannii and K. pneumoniae between 2007 and 2013 were used in this study. The antimicrobial susceptibility of the isolates was determined using the disk diffusion method following the Clinical and Laboratory Standards Institute guidelines. The A. baumannii isolates were subjected to a panel of 20 antibiotics, while K. pneumoniae isolates were subjected to a panel of 22 antibiotics. Data were analyzed using descriptive statistics and presented using tables and figures. Results: Twenty (n = 20) A. baumannii isolates were isolated from bronchoalveolar lavage, foreign objects, bone, urine, skin, blood, ear, nasal, and oral cavity. Almost all A. baumannii (95%, 19/20) isolates were resistant to at least one antibiotic, and 60% (12/20) were multidrug-resistant (MDR). Klebsiella pneumoniae (n = 56) was isolated from urine, foreign objects, abscesses, ears, eyes, tracheal aspirations, bronchoalveolar lavages, eyes, abdominal aspirates, anal glands, bones, and intestinal and lung biopsies. All K. pneumoniae (100%, 56/56) isolates were resistant to at least one antibiotic, and 98% (55/56) were MDR. Conclusion: Both A. baumannii and K. pneumoniae were isolated in various clinical tissue samples and exhibited a high prevalence of resistance to multiple antibiotics. In addition, these bacteria exhibited a high prevalence of resistance to β-lactam compared to other classes of antibiotics, which is likely to impact treatment options and patient prognosis.