Miracle-dz/UniFAR-FTUs huggingface dataset:
Effect of Designed Practice Guidelines on Nurses’ Performance and Outcome of Children with Head Injuries

Contexts Acute head injury resulting from a trauma to the head, leading to brain injury or bleeding within the brain, it can cause edema and hypoxia. Head injury is the leading cause of death in the first four decades of life. Effective nursing management strategies for children with severe traumatic brain injury are still a remarkable issue and a difficult task for neurologists, neurosurgeons, and nurses. Aim: To evaluate the effect of designed practice guidelines on nurses' performance regarding the care of children with head injuries. Methods: A quasi-experimental research design utilized to conduct the current study on pediatric neurosurgery departments of Benha University Hospital and Benha Teaching Hospital. A purposive sample of 72 children with head injuries and a convenient sample of all available nurses. They were 62 nurses who are working on the previously mentioned study settings. Four tools used to collect data in this study. A structured interviewing questionnaire sheet developed to assess the studied nursing personal characteristic of the studied nurses and nurses' knowledge regarding head injuries. Child medical data record developed to assess children's personal and head injuries characteristics for children. Glasgow coma scale adopted to assess the child conscious level. Observational checklists to assess the actual nurses' practices regarding the care of children with head injuries. Results: There was a statistically significant improvement in nurses' knowledge and practice regarding the care of children with head injuries before and after the implementation of designed practice guidelines (p˂0.001). There was a statistically significant improvement regarding the occurrence of convulsion after the implementation of the program. Conclusion: The study concluded that the implementation of designed practice guidelines for nurses improves their knowledge and practice as well as reduced occurrence of frequency, duration, and timing of convulsion, which support the current research hypotheses. The study emphasizing the importance of implementing of designed practice guidelines for nurses caring of children with a head injury to reduce the occurrence of head injury complications, which is an effective and safe non-invasive intervention in neurosurgery and emergency departments as a standard of care for all head-injured children.
Antioxidant actions of olive leaf extract (Olea europaea L.) on reactive species scavengers

This study aimed to evaluate in vitro antioxidant action of olive leaf extract (Olea europaea L.) by: i) Trolox equivalent antioxidant capacity (TEAC) by ABTS•+, DPPH and Ferric reducing antioxidant power (FRAP) assays; ii) scavenging of superoxide anion (O2•-), hypochlorous acid (HOCl) and nitric oxide (NO), compared to ascorbic acid. Results showed TEAC values as 0.148±0.015, 0.215±0.076 and 0.282±0.023 gram of trolox equivalent per gram of dry extract weight, to respective ABTS•+, DPPH• and FRAP. Olive leaf extract was better antioxidant than ascorbic acid on O2•- scavenging, at concentrations over 50 µg/mL; similar effects on NO scavenging for both was seen and on HOCl inhibition, the extract showed lower antioxidant action than ascorbic acid at all concentrations. Olive leaf extract showed potentiality to be used as antioxidant in biological systems.
miR-9-1 Is a New Circulating Biomarker for Higher-grade Meningioma Regulated via the EGFR-FOS Network

Background: Meningiomas are the most common primary CNS tumors. According to the World Health Organization Classification (WHO), they are classified as benign (grade I), atypical (grade II), and anaplastic/malignant (grade III). Chemotherapy has proven ineffective in treating these tumors, which are primarily managed by surgery, radiotherapy, or a combination of them. Morbidity and mortality correlate with meningioma grade. Currently, risk assessment for treatment is based on the radiological assessment of tumor size, tumor growth rate, and/or clinical progression of symptoms. Methods: We performed a cancer miRNA array in an in vitro model of meningioma in order to identify circulating biomarkers in meningioma patients. We validated the miRNA biomarker candidate in cells and tissues and analyzed its regulation. We then investigated expression in tissues and blood. Results: We identified miR-9-1 as significantly overexpressed in atypical and anaplastic cells compared to benign. We further demonstrated that miR-9-1 overexpression is due to increased levels of FOS via upregulation of the EGFR receptor, and showed that miR-9-1 and FOS are upregulated in a cohort of higher-grade meningioma biopsies. Next, we isolated circulating exosomes from meningioma patients’ serum samples, and found higher levels of miR-9-1 in higher-grade compared to low-grade meningiomas patients. Conclusions: Overall, our study shows overexpression and the mechanism of miR-9-1 regulation and suggests miR-9-1 as a novel circulating biomarker candidate to identify tumor grade in meningioma.
Exploring the Needs of the B40 Community in Agricultural Activities for Social Entrepreneur Activists

Purpose: One of the ways to improve the economy of the B40 (Bottom 40%) community in agricultural activities is to identify and study their need. This study aims to explore the requisites of the B40 community in agricultural activities for social entrepreneur activists. Design. Data is obtained from individuals and by observation. Due to restrictions on movement control orders caused by COVID-19, in Malaysia, some of them are approached by phone call interview or video-conferencing. Methodology: Qualitative research methods have been considered the most appropriate and suitable in this case study. Approach: Five participants were involved in this study whom the government once assisted in their agricultural activities. Findings: This study found six essential components of the needs of the B40 community in their agricultural activities. The six components are training, capital, monitoring, marketing, supply chain, and business networking. Originality of the Research: This study's novelty lies in the conditions that social entrepreneur activists and government agencies need to consider when it comes to helping the B40 community in agricultural activities. Such efforts can sustain the income and agricultural activities that they carry out.
Gel Dosimetry with Radio-Fluorogenic Coumarin

In radiotherapy, accurate deposition of energy to the targeted volume is vital to ensure 9 effective treatment. Gel dosimeters are attractive detection systems, as tissue substitutes with 10 potential to yield three-dimensional dose distributions. Radio-fluorogenesis is creation fluorescent 11 chemical products in response to energy deposition from high-energy radiation. This report shares 12 studies of a radio-fluorogenic gel dosimetry system, gelatin with coumarin-3-carboxlyic acid 13 (C3CA), for the quantification of imparted energy. Aqueous solutions exposed to ionizing radiation 14 result in the production of hydroxyl free radicals through water radiolysis. Interactions between 15 hydroxyl free radicals and coumarin-3-carboxylic acid produce a fluorescent product. 16 7-hydroxy-coumarin-3-carboxylic acid has a blue (445 nm) emission, following UV to near UV 17 (365–405 nm) excitation. Effects of C3CA concentration and pH buffers were investigated for this 18 system. The response of the system was explored with respect to strength, type, and exposure rate 19 of high-energy radiation. Results show a linear dose response relationship with a dose-rate 20 dependency and no energy or type dependencies. This report supports the utility of gelatin-C3CA 21 for phantom studies of radio-fluorogenic processes. 22
Individual differences in epistemically suspect beliefs: the role of analytic thinking and susceptibility to cognitive biases

Abstract The endorsement of epistemically suspect (i.e., paranormal, conspiracy, and pseudoscientific) beliefs is widespread and has negative consequences. Therefore, it is important to understand the reasoning processes – such as lower analytic thinking and susceptibility to cognitive biases – that might lead to the adoption of such beliefs. In two studies, I constructed and tested a novel questionnaire on epistemically suspect beliefs (Study 1, N = 263), and used it to examine probabilistic reasoning biases and belief bias in syllogistic reasoning as predictors of the endorsement of those beliefs, while accounting for analytic thinking and worldview variables (Study 2, N = 397). Probabilistic reasoning biases, analytic thinking, religious faith, and political liberalism consistently predicted various epistemically suspect beliefs, whereas the effect of syllogistic belief bias was largely restricted to pseudoscientific beliefs. Further research will be needed to examine the role the biased evaluation of evidence plays in the endorsement of epistemically suspect beliefs.
Performance of Reverse Osmosis Membranes in the Treatment of Flue-Gas Desulfurization (FGD) Wastewaters

Reverse osmosis (RO) was studied to reduce salinity of flue gas desulfurization (FGD) wastewaters after softening with Na2CO3·H2O and ultrafiltration (UF). Two commercial thin film composite polyamide RO membranes (SWC-2540 and ESPA-2540, from Hydranautics) in spiral-wound configuration were tested and their performance in terms of salinity reduction as well as permeate flux, fouling index and water recovery was evaluated. Experimental runs were performed according to the feed and bleed configuration in selected operating conditions. For the SWC-2540 membrane experiments were also performed in total recycle configuration in order to evaluate the effect of operating pressure on permeate flux and quality. Experimental results indicated that the SWC-2540 membrane showed a better performance in the rejection of ions: Mg2+ ions were completely rejected, while the rejection towards monovalent ions such as Na+ was of about 95.5%. The ESPA-2540 membrane showed rejections towards Ca2+ and Mg2+ higher than 86.5% whilst the observed rejection towards Na+ was of 80%. For the SWC-2540 membrane an increased rejection for Ca2+ and Na+ ions was observed by increasing the operating pressure in the range 16-50 bar. Mg2+ ions were totally rejected independently by the operating pressure.
Assessment of Household Food Security Situation during the Covid-19 Lockdown in Kenya

Food security remains a key challenge in Kenya. A household is considered to be food insecure when they lack physical and economic access to safe, sufficient and nutritious food that meets their dietary needs and food preferences for an active and healthy life at all times. In the last six months or so, vulnerability to food insecurity has been exacerbated by the raging effects of COVID-19 pandemic, which pushed the Government of Kenya to impose a partial lockdown in the month of April, 2020, in the counties of Nairobi and Mombasa. This survey sought to assess the effects of the ongoingCOVID-19 lockdown on household food security situation in Kenya. A survey was conducted from June to July 2020 through a structured questionnaire which was administered through online social networks. A total of 444 responses were received, but only 80 were completely filled. Quantitative data were collected on the socio-demographic characteristics, dietary practices and coping strategies based on a set of questions to assess behavioral responses to manage incipient household food shortage. Data were analyzed using Statistical Package for Social Sciences (SPSS) version 23.0. Descriptive statistics such as mean, percentages and frequencies were carried out; relationships between the variables were assessed using chi-square test, Pearson correlation and multiple linear regression. Significance levels were determined at 95 percent confidence interval where a p-value of less than 0.05 was considered significant. The prevalence of low, medium and high dietary diversity scores were 7.5 percent, 17.5 and 75 percent, respectively, implying that the majority of the respondent households were food secure with pockets of food insecure households within the Nairobi Metropolitan region. There was a significant relationship between household dietary diversity and household income source (χ²=7.71, p=0.02), household perceived economic pressure during the COVID-19 lockdown (χ²=20.37, p<0.01), and household perceived ability to meet their food needs (χ²=18.01, p<0.01). Consumption of less preferred and less expensive foods was the most (30 percent) often used coping strategy against food insecurity. The study recommends putting up mitigation strategies to support pockets of food insecure households during lockdowns imposed by state agencies in the wake of the COVID-19 pandemic.
Modelling the impact of increased lateral connectivity on nutrient retention in Austrian Danube floodplains

In the last centuries, rivers in Central Europe have severely suffered from hydro-morphological alterations and excessive nutrient inputs. Their adjacent floodplains have the ability to retain transported nutrients in case of inundation, but are subject to progressing decoupling from the main river stem. In the Austrian Danube Floodplain National Park, restoration measures have been carried out and are planned for the near future to increase lateral connectivity in accordance with navigation purposes.
Pengembangan Video Praktikum Kimia Materi Larutan Eletrolit dan Nonelektrolit Ramah Difabel Rungu “VIP RUNGU”

Praktikum kimia merupakan rangkaian kegiatan yang dapat memungkinkan siswa untuk menerapkan berbagai keterampilan proses sains. Praktikum dilakukan di sekolah inklusi diikuti oleh seluruh siswa termasuk siswa tunarungu. Tunarungu diartikan sebagai seorang yang kekurangan atau kehilangan kemampuan dengar sehingga dapat mempengaruhi kemampuan komunikasi lisannya. Keterbatasan komunikasi lisan, umumnya menjadi salah satu faktor kesulitan belajar bagi siswa difabel rungu. Permasalahan yang muncul dalam proses pembelajaran di sekolah tidak selalu diadakan praktikum dengan berbagai penyebab dan kebutuhan. Oleh sebab itu, diperlukan media yang dapat memudahkan siswa difabel rungu dalam menerima materi praktikum kimia. Penelitian ini bertujuan untuk mengembangkan video praktikum kimia materi larutan elektrolit dan nonelektrolit yang ramah difabel rungu. Penelitian ini dilakukan uji kualitas oleh pakar ahli dan direspon oleh pengguna terhadap produk “VIP RUNGU”. Pengembangan media dilakukan dengan pendekatan model 4-D yang meliputi tahap definisi, perancangan, dan pengembangan. Uji kualitas produk dilakukan dengan metode expert judgement menggunakan instrumen lembar angket penilaian kualitas ahli untuk mendapatkan skor kualitas. Analisis respon pengguna menggunakan instrumen lembar angket respon siswa untuk mengetahui persepsi pengguna terhadap produk “VIP RUNGU”. Kualitas media yang dikembangkan berdasarkan hasil penilaian ahli pendidikan inklusi masuk dalam kategori Sangat Baik (SB) dengan respon siswa terhadap media “VIP RUNGU” mendapatkan persentase keidealan sebesar 90% yang menunjukkan kepuasan responden terhadap media yang dikembangkan.
Discriminant Models for the Prediction of Viral Shedding Time and Disease Progression in COVID-19

Background COVID-19 infection can cause life-threatening respiratory disease. This study aimed to fully characterize the clinical features associated with postponed viral shedding and disease progression, then develop and validate two prognostic discriminant models. Methods This study included 125 hospitalized patients with COVID-19. 44 parameters were recorded, including age, gender, underlying comorbidities, epidemic features, laboratory indexes, imaging characteristics and therapeutic regimen, et al. F-test and χ2 test were used for feature selection. All models were developed with 4-fold cross-validation, and the final performances of each model were compared by the Area Under Receiving Operating Curve (AUROC). After optimizing the parameters via L2 regularization, prognostic discriminant models were built to predict postponed viral shedding and disease progression of COVID-19 infection. The test set was then used to detect the predictive values via assessing models sensitivity and specificity. Results 69 patients had a postponed viral shedding time (> 14 days), and 28 of 125 patients progressed into severe cases. Eleven and six demographic, clinical features and therapeutic regimen were significantly associated with postponed viral shedding and disease progressing, respectively (p < 0.05). The optimal discriminant models are: y1 (postponed viral shedding) = -0.244 + 0.2829x1 (the interval from the onset of symptoms to antiviral treatment) + 0.2306x4 (age) + 0.234x28 (Urea) − 0.2847x34 (Dual-antiviral therapy) + 0.3084x38 (Treatment with antibiotics) + 0.3025x21 (Treatment with Methylprednisolone); y2 (disease progression) = -0.348–0.099x2 (interval from Jan 1st, 2020 to individualized onset of symptoms) + 0.0945x4 (age) + 0.1176x5 (imaging characteristics) + 0.0398x8 (short- term exposure to Wuhan) − 0.1646x19 (lymphocyte counts) + 0.0914x20 (neutrophil counts) + 0.1254x21 (neutrphil/lymphocyte ratio) + 0.1397x22 (C-Reactive Protein) + 0.0814x23 (Procalcitonin) + 0.1294x24 (Lactic dehydrogenase) + 0.1099x29 (Creatine kinase). The output ≥ 0 predicted postponed viral shedding or disease progressing to severe/critical state. These two models yielded the maximum AUROC, and faired best in terms of prognostic performance (sensitivity of 73.3%, 75%, and specificity of 78.6%, 75% for prediction of postponed viral shedding and disease severity, respectively). Conclusion The two discriminant models could effectively predict the postponed viral shedding and disease severity, and be used as early-warning tools for COVID-19.
Advanced dose calculation algorithm in superficial brachytherapy – the impact of tissue inhomogeneity on treatment plan dosimetry

Purpose Given tissue inhomogeneity and lack of backscatter media, superficial brachytherapy necessitates more accurate dosimetry than TG-43 formalism. However, the introduction of modern model-based dose calculation algorithms into clinical practice should be carefully evaluated. The aim of this work was to compare dose distributions calculated with TG-43 and advanced collapsed cone engine (ACE) algorithms for individual multi-catheter moulds, and investigate the impact of target size and the lack of bolus to differences between plans. Material and methods Eleven treatment plans for individual mould multi-catheter high-dose-rate brachytherapy (IMM HDR) were selected for retrospective analysis. All treatment plans were initially calculated with TG-43 formula and re-calculated using ACE algorithm. Plan re-calculation with ACE was repeated for each plan in order to assess the impact of bolus. To evaluate differences between TG-43 and ACE dose distributions, dose-volume histogram (DVH) parameters for each ROI were compared. Dmax (maximal point dose), D0.1cc, and D2cc were calculated for each risk’s organ (OARs) and for external contour. For clinical target volume (CTV), D98, D90, D50, CTV coverage (CTV-V100), and dose delivered to reference point were compared between the plans. Results A significantly lower values (p < 0.05) of CTV parameters were observed for treatment plans calculated with ACE algorithm comparing to TG-43. Further analysis showed that differences between CTV-V100 for ACE and TG-43 plans depended on CTV volume. Dosimetric parameters for OARs were significantly lower in ACE plans than those of TG-43. Only D2cc for external and D0.1cc for both eye lenses in ACE plans were insignificantly different comparing to TG-43 plans. Conclusions Results show that differences between dosimetric parameters are statistically significant. However, their clinical relevance is still undetermined. Careful re-evaluation of the clinical results based on long-term research on TG-43 is necessary to safely introduce modern algorithms to clinical practice.
Microwave-assisted synthesis of biologically active amide derivatives of naphthenic acids under neat conditions

Within the field of green chemistry, a noticeable results were obtained in the solvent-free synthesis of amide derivatives of naphthenic acids under microwave irradiation. Naphthenic acid amides, anilides, and morpholides were synthesized directly from free carboxylic acids and amines in the absence of solvent and catalyst under high-temperature heating in a closed-vessel system of microwave reactor. With this new and efficient method, different primary, secondary, and tertiary amide derivatives of naphthenic acids were obtained in good to excellent yields. Synthesized derivatives were assayed as plant rooting agents for their stimulative effects on the formation of adventitious roots in sunflower cuttings and susceptibility for growth stimulation of Pseudomonas sp. strains.
Prediction of Quality of Life Based on Spiritual Intelligence and Resiliency in Mothers of Children with Behavioral Problems

1 PhD Student in Counseling, Department of Counseling and Psychology, Faculty of Human Sciences, University of Hormozgan, Bandar Abbas, Iran. 2 Assistant Professor, Department of Clinical Psychology, Young Research and Elite Club, Bandar Abbas Branch, Islamic Azad University, Bandar Abbas, Iran. 3 MA, Occupational Counseling, Allameh Tabataba’i University, Faculty of Psychology and Educational Sciences, Tehran, Iran. 4 Mother and Child Welfare Research Center, Hormozgan University of Medical Sciences, Bandar Abbas, Iran.
Seroprevalence of Leptospirosis among Water Buffaloes, Pigs, and dogs in Selected Areas in the Philippines, 2007 to 2008

Background. Domestic animals are known to be either maintenance or accidental hosts of Leptospira. Determination of seroprevalence of leptospirosis among these animals is of great importance due to their close association with humans, economic loss as well as the public and veterinary health problems caused by the said zoonosis. Objective. This study aimed to determine the seroprevalence of leptospirosis among water buffaloes, pigs, and dogs in selected areas in the Philippines. Methods. Microscopic agglutination test (MAT) was used to test for leptospirosis. Testing was done from January 2007 to August 2008. Results. With the cut-off titer set at 1:80, the MAT-positivity rates were 82%, 67%, and 79% for 190 water buffaloes, 45 pigs, and 106 dogs, respectively. The most common prevailing serovars detected were Hardjo, Tarassovi, and Hebdomadis for water buffaloes; Semaranga, Grippotyphosa, and Patoc for pigs; and, Manilae, Patoc, and Autumnalis for dogs. MAT-positivity rates among these animals in terms of age (except for water buffaloes), sex and sample collection sites were not statistically significant. No Leptospira was isolated from the blood, urine, and kidney samples of these animals. Conclusion. Results indicate a high seroprevalence of leptospirosis among the animals studied and that several pathogenic leptospires are causing infection in these animals.