Miracle-dz/UniFAR-FTUs huggingface dataset:
Partners in play: Exploring ‘playing with’ children living with severe physical and intellectual disabilities

Introduction Play occupation is central to children’s occupational lives and play is established as a fundamental right. While children with disabilities are at increased risk of play deprivation, few studies have explored the play occupation of children living with severe physical and intellectual disabilities. Method Informed by an ethnographic approach, this qualitative study involved 17 participants including five families of children with severe disabilities and six classroom staff. Methods combined observations of children’s play with adult interviews and focus groups to explore factors that influence play in home and school contexts. Findings were analysed using thematic analysis. Findings Three themes emerged: (a) play as an occupation, play as an activity; (b) an empowered and empowering play partner; (c) the ‘just-right’ play object and environment. Conclusion The influence of an empowering and empowered play partner combined with the suitability of the object and environment was central to successful play. A commitment to play for fun, for the wellbeing of these children, and by ‘playing with’ and not ‘doing-to’ the child was fundamental. Although the findings are specific to this study, play facilitators may use them to inform future play interactions through an enhanced understanding of empowerment and enablement for successful play occupation.
Description of gas hydrates equilibria in sediments using experimental data of pore water potential

The purpose of the work is to show how to employ the experimental data from geocryology and soil physics for thermodynamic calculations of gas hydrate phase equilibria by taking into account pore water behavior in sediments. In fact, thermodynamic calculation is used here to determine the amount of non-clathrated pore water content in sediments in equilibrium with gas and hydrate phases. A thermodynamic model for pore water behavior in sediments is developed. Taking into account the experimental water potential data, the model calculations show good agreement with the experimentally measured unfrozen water content for different pressure and temperature conditions. The proposed thermodynamic model is applied for calculations of three-phase equilibria: multicomponent gas phase (methane, natural gas, etc.) – pore water in clay, sand, loamy sand, etc. – bulk (or pore) hydrate. As a result, correlations have been established between unfrozen and non-clathrated water content in natural sediments.
Group B Streptococcus and the vaginal microbiome among pregnant women: a systematic review

Background Vaginal microbiome studies frequently report diversity metrics and communities of microbiomes associated with reproductive health outcomes. Reports of Streptococcus agalactiae (also known as Group B Streptococcus or GBS), the leading cause of neonatal infectious morbidity and mortality, are notably lacking from the studies of the vaginal microbiome, despite being a known contributor to preterm birth and other complications. Therefore, the purpose of this systematic review was to explore the frequency of GBS reporting in vaginal microbiome literature pertaining to pregnancy and to examine methodological bias that contributes to differences in species and genus-level microbiome reporting. Lack of identification of GBS via sequencing-based approaches due to methodologic or reporting bias may result incomplete understanding of bacterial composition during pregnancy and subsequent birth outcomes. Methodology A systematic review was conducted following the PRISMA guideline. Three databases (PubMed, CINAHL, and Web of Science) were used to identify papers for review based on the search terms “vaginal microbiome”, “pregnancy”, and “16S rRNA sequencing”. Articles were evaluated for methods of DNA extraction and sequencing, 16S region, taxonomy classification database, number of participants or vaginal specimens, and pregnancy trimester. Results Forty-five research articles reported employing a metagenomic approach or 16S approach for vaginal microbiome analysis during pregnancy that explicitly reported taxonomic composition and were included in this review. Less than 30% of articles reported the presence of GBS (N = 13). No significant differences in methodology were identified between articles that reported versus did not report GBS. However, there was large variability across research methods used for vaginal microbiome analysis and species-level bacterial community reporting. Conclusion Considerable differences in study design and data formatting methods may contribute to underrepresentation of GBS, and other known pathogens, in existing vaginal microbiome literature. Previous studies have identified considerable variation in methodology across vaginal microbiome studies. This study adds to this body of work because in addition to laboratory or statistical methods, how results and data are shared (e.g., only analyzing genus level data or 20 most abundant microbes), may hinder reproducibility and limit our understanding of the influence of less abundant microbes. Sharing detailed methods, analysis code, and raw data may improve reproducibility and ability to more accurately compare microbial communities across studies.
Direct and plant‐mediated effects of climate on bird diversity in tropical mountains

Abstract Aim Although patterns of biodiversity across the globe are well studied, there is still a controversial debate about the underlying mechanisms and their generality across biogeographic scales. In particular, it is unclear to what extent diversity patterns along environmental gradients are directly driven by abiotic factors, such as climate, or indirectly mediated through biotic factors, such as resource effects on consumers. Location Andes, Southern Ecuador; Mt. Kilimanjaro, Tanzania. Methods We studied the diversity of fleshy‐fruited plants and avian frugivores at the taxonomic level, that is, species richness and abundance, as well as at the level of functional traits, that is, functional richness and functional dispersion. We compared two important biodiversity hotspots in mountain systems of the Neotropics and Afrotropics. We used field data of plant and bird communities, including trait measurements of 367 plant and bird species. Using structural equation modeling, we disentangled direct and indirect effects of climate and the diversity of plant communities on the diversity of bird communities. Results We found significant bottom‐up effects of fruit diversity on frugivore diversity at the taxonomic level. In contrast, climate was more important for patterns of functional diversity, with plant communities being mostly related to precipitation, and bird communities being most strongly related to temperature. Main conclusions Our results illustrate the general importance of bottom‐up mechanisms for the taxonomic diversity of consumers, suggesting the importance of active resource tracking. Our results also suggest that it might be difficult to identify signals of ecological fitting between functional plant and animal traits across biogeographic regions, since different species groups may respond to different climatic drivers. This decoupling between resource and consumer communities could increase under future climate change if plant and animal communities are consistently related to distinct climatic drivers.
Whipple Procedure: A Five-Year Clinical Experience in Tertiary Care Center

Introduction: Whipple procedure is one of the major surgeries performed in tertiary care centers. Once considered a high mortality procedure is now being practicing with mortality declining to less than 5%. This study describes our five-year experience of the Whipple procedure in terms of preoperative, operative, and postoperative parameters of patients undergoing surgery in a local tertiary care setting. Material and Methods: This was a non-randomized interventional study that was conducted at the Surgical Department of Services Hospital Lahore from January 2014 to December 2018. A total of 57 Whipple procedures were performed during this period. Demographic data, presenting symptoms, physical signs, past medical history, preoperative stenting details, intra-operative duration of surgery, postoperative course and complications, pathology, and causes of postoperative death were collected on a pre-designed questionnaire. Data were entered and analyzed by using SPSS 22 (IBM Corp., Armonk, USA). Results: Out of 57 patients, 19 were females and 38 were males. The mean age of patients was 53±05 years. The most common presenting symptom was jaundice 39 (68.4%), followed by abdominal pain 32 (56.1%). The mean size of the tumor on CT-scan was 2.8±1.4 cm, the mean operation time was 315±38.3 min, mean blood loss during surgery was 500±130 ml, and mean hospital stay was 10±6 days. The major postoperative complication was the pancreatic fistula (12%). Twenty-one out of 39 patients presented with jaundice had undergone preoperative biliary stenting by endoscopic retrograde biliary stenting. The most common histological diagnosis was adenocarcinoma of pancreas 19 (33.3%). Out of 57 patients, nine (15.8%) patients expired in the first 30 days and the most frequent cause of mortality was septic shock. Conclusion: In this study, the most common presentation of patients undergoing Whipple procedure was obstructive jaundice, the most frequent operative complication was pancreatic fistula, and the most prevalent histopathology was carcinoma of the pancreas. Perioperative parameters such as mean operative time, mean blood loss during surgery, and mean length of hospital stay were comparable with other studies. However, mortality in this study was slightly higher. It can be concluded that with meticulous surgical technique, securing hemostasis strictly and standard critical care postoperatively can decrease morbidity and mortality after the Whipple procedure.
Mobilising knowledge: an action design research case study of using technology to safeguard an endangered nature-based tourism attraction

Abstract This paper considers how an Action Design Research (ADR) research methodology can contribute to impactful research in sustainable tourism. ADR arguably combines the best of Action Research with Design Science, by solving an applied problem within its contextual setting (a feature of Action Research) and drawing wider lessons or universal principles from the solution (a feature of Design Science). It argues that approaches like ADR are required to address what is a fundamentally goal-oriented (through the very definition of sustainable tourism) area of research, and bridge the academic-practitioner divide. The paper presents an ADR case study on using technology to build the eco-literacy of tourists visiting Australia’s Great Barrier Reef. This natural attraction represents a highly complex ecosystem, in an educationally challenging (underwater) environment, surrounded by political and scientific controversy. The case study involves the creation of a virtual reality interpretive game (the artefact) to illustrate the four stages of ADR, namely, Problem Formulation; Build, Intervene, Evaluate; Reflect and Learn; Formalise Learning. The case study highlights the importance of ADR’s principles of “reciprocal shaping”, “mutually influencing roles” and “authentic and concurrent evaluation” to bridge the gap between practice and theory, and build impactful research that can support more sustainable tourism.
Rebuttals as deracializing strategies for African American and white candidates

Abstract The study of American racial politics has long focused on the conditions that activate racial animosity. A central line of research demonstrates that campaign messages that highlight negative stereotypes of African Americans can activate whites' racial attitudes. However, little is known about whether this activation can be overcome. I develop a theory of racial deactivation and test its predictions with two survey experiments. I find that explicitly criticizing the racial nature of an attack restores support for white candidates, but not African American candidates. However, African American and white candidates fare equally well using two rebuttal styles: a credible, non-racial justification of the attacked action or an explicit racial critique combined with the justification. The results have implications for how race affects campaigns, the susceptibility of the American public to racial cues, and campaign strategy.
Touristic SME’s Competitiveness in the Light of Present Challenges—A Qualitative Approach

Competitiveness of SMEs (Small or Medium Enterprise) within the tourism field has been of a great interest for many scholars over time. Due to the crisis conditions specific to the present time, the issue of competitiveness becomes a very sensitive one, giving rise to sometimes contradictory points of view. Our research aims to analyze the opinions and perceptions of SME managers in the field of tourism in terms of the concept of competitiveness, how to measure it and sources of competitiveness still viable within the context of the current crisis or specific to it, etc. In order to be able to properly analyze the above, qualitative research was initiated and conducted in the form of an in-depth interview with 42 Romanian SME managers in the tourism field. The results of the study reflect a mature approach of managers in terms of possible new sources of competitiveness—the emphasis on technical solutions capable of managing the socio-medical dimensions of tourism consumer behavior, a prevalence for an organic growth strategy and for additional investments in qualified personnel, as well as online management of most aspects related to services and openness to collaboration within tourism clusters.
THE STUDENTS' MATHEMATICAL PROBLEM-SOLVING ABILITIES, SELF-REGULATED LEARNING, AND VBA MICROSOFT WORD IN NEW NORMAL: A DEVELOPMENT OF TEACHING MATERIALS

Received Sep 30, 2020 Revised Oct 15, 2020 Accepted Nov 12, 2020 The new normal period makes ICT-based education the spearhead of the implementation of learning. This becomes an obstacle and a challenge for students, especially in the mathematical problem-solving ability (MPSA), which is very important for students because it is a prior mathematical ability and is included in HOTS. Self-regulated learning in mathematics (SRL) also has a significant role in adapting to learning in the new normal and influences students' mathematical learning outcomes. However, the facts on the ground show that these two abilities are still low. To solve this problem, the researchers developed VBA Microsoft Word-based teaching materials on the relevant polyhedron materials for use so that learning would be more optimal. The method used in this research is an experimental method with a pretestposttest control group design. The population is all the students in Cimahi City, while the sample is two classes randomly selected. This study indicates that VBA Microsoft Word-based teaching materials are appropriate to be applied in the new normal period, as indicated by the results of the achievement and improvement of MPSA and SRL of students is better than ordinary learning. There is an association between MPSA and SRL and positive response even though they still have difficulty making mathematical models on MPSA questions. Students are more enthusiastic in learning and don't get bored quickly; in line with the challenges of the new normal, the industrial revolution 4.0, and the learning curriculum, learning is more structured, interactive, effective, and efficient.
Probabilistic Model for Real-Time Flood Operation of a Dam Based on a Deterministic Optimization Model

This paper presents a real-time flood control model for dams with gate-controlled spillways that brings together the advantages of an optimization model based on mixed integer linear programming (MILP) and a case-based learning scheme using Bayesian Networks (BNets). A BNet model was designed to reproduce the causal relationship between inflows, outflows and reservoir storage. The model was trained with synthetic events generated with the use of the MILP model. The BNet model produces a probabilistic description of recommended dam outflows over a time horizon of 1 to 5 h for the Talave reservoir in Spain. The results of implementing the BNet recommendation were compared against the results obtained while applying two conventional models: the MILP model, which assumes full knowledge of the inflow hydrograph, and the Volumetric Evaluation Method (VEM), a method widely used in Spain that works in real-time, but without any knowledge of future inflows. In order to compare the results of the three methods, the global risk index (Ir) was computed for each method, based on the simulated behavior for an ensemble of hydrograph inflows. The Ir values associated to the 2 h-forecast BNet model are lower than those obtained for VEM, which suggests improvement over standard practice. In conclusion, the BNet arises as a suitable and efficient model to support dam operators for the decision making process during flood events.
Freeports and the Hidden Value of Art

At first glance, the global art trade—currently valued around $60 billion—is a miniscule piece of global economic production. But due to the unregulated nature of the art market, it serves a key function within the larger network of the accumulation and distribution of capital worldwide. This deregulated market intersects with the offshore domain in freeports, an archipelago of tax-free storage facilities that stretch from Singapore to Geneva to Delaware. The burgeoning of freeports globally suggests that speculation has become a more prominent pattern of art investment, but it also demonstrates that tax avoidance is a goal of such speculators and the result is that more art works are being taken out of circulation and deposited in vaults beyond the view of regulatory authorities. Despite its size, the art trade can demonstrate broader trends in international finance and, by examining offshore art storage that occurs in freeports, it will be possible to locate some of the hidden mechanisms that allow the global art market to flourish on the margins of the economy as well as to perceive a shift in which the economic value of art works predominates over their cultural value.
Use of Venetoclax in Patients with Relapsed or Refractory Acute Myeloid Leukemia: The PETHEMA Registry Experience

Simple Summary The use of venetoclax combined with hypomethylating agents or low-dose cytarabine in patients with newly diagnosed acute myeloid leukemia unfit for intensive chemotherapy was recently approved. However, the evidence in relapse or refractory patients is still scarce. The cohort of patients included in our study was heavily pretreated and had a poor performance status. It is still necessary to identify those patients at higher risk of early death who would not benefit from this type of treatment. For these ultra-high-risk patients, other treatment strategies should be followed. Abstract The effectiveness of venetoclax (VEN) in relapsed or refractory acute myeloid leukemia (RR-AML) has not been well established. This retrospective, multicenter, observational database studied the effectiveness of VEN in a cohort of 51 RR-AML patients and evaluated for predictors of response and overall survival (OS). The median age was 68 years, most were at high risk, 61% received ≥2 therapies for AML, 49% had received hypomethylating agents, and ECOG was ≥2 in 52%. Complete remission (CR) rate, including CR with incomplete hematological recovery (CRi), was 12.4%. Additionally, 10.4% experienced partial response (PR). The CR/CRi was higher in combination with azacitidine (AZA; 17.9%) than with decitabine (DEC; 6.7%) and low-dose cytarabine (LDAC; 0%). Mutated NPM1 was associated with increased CR/CRi. Median OS was 104 days (95% CI: 56–151). For the combination with AZA, DEC, and LDAC, median OS was 120 days, 104 days, and 69 days, respectively; p = 0.875. Treatment response and ECOG 0 influenced OS in a multivariate model. A total of 28% of patients required interruption of VEN because of toxicity. Our real-life series describes a marginal probability of CR/CRi and poor OS after VEN-based salvage. Patients included had very poor-risk features and were heavily pretreated. The small percentage of responders did not reach the median OS.
Determining the Entrepreneurial and Intrapreneurial Intentions of Student Pharmacists in Iran

Objective. To identify factors and entrepreneurial characteristics associated with entrepreneurial and intrapreneurial intentions among Doctor of Pharmacy (PharmD) students in Iran. Methods. First, the Entrepreneurial-Intrapreneurial Pharmacist Questionnaire (EIPQ), which was developed in the United States, was translated from English to Persian. The paper-based Persian-EIPQ questionnaire was then tested in a convenience sample of student pharmacists enrolled in pharmacy schools in Iran. The entrepreneurial characteristics questionnaire was evaluated using exploratory factor analysis with varimax rotation. Internal consistency was examined using Cronbach alpha. The association of demographics and educational variables and entrepreneurial characteristics with entrepreneurial and intrapreneurial intentions was determined using a multiple linear regression model. Results. A total of 504 surveys, 98.6% of the completed questionnaires received, were analyzed. A majority of the participants were female (75.8%) and from 18 to 25 years old (92.2%). Entrepreneurial intention had a positive and significant association with risk-taking propensity, leadership self-efficacy, autonomy, achievement motivation, and having an entrepreneur in the family. Intrapreneurial intention had a positive and significant association with risk-taking propensity, leadership self-efficacy, achievement motivation, people liking, attending a private school, and having an entrepreneur in the family. Conclusion. Based on the findings, student pharmacists with higher levels of risk-taking propensity, achievement motivation, leadership self-efficacy, autonomy, and people liking may be more likely to have greater levels of entrepreneurial and/or intrapreneurial intention.
Effect of Organizational Sponsorship, Career Management Behaviour and Proactive Personality in Predicting Managers’ Subjective Career Success

The main aim of the study was to examine the role of organizational sponsorship, career management behaviour and proactive personality in predicting subjective career success of managerial staff in large scale manufacturing firms in Kenya. Primary data was collected using a sample of 255 managers from large scale manufacturing firms in Kenya based on descriptive survey. Hypothesis was tested using hierarchical regression model. The findings indicate that the joint effect of the predictor variables was greater than their individual effect on subjective career success. The study recommends that large manufacturing firms should facilitate their staff’s career success by providing them with organizational sponsorship programmes. The findings also point out the need for the staff to be proactive and to adopt suitable career management behaviour that can enhance their achievement of career success. Future researchers may benefit from the already established conceptual and methodological reference in their pursuit for further studies with regards to this area in different contexts.