Miracle-dz/UniFAR-FTUs huggingface dataset:
Establishment of Reference Values of Serum PTH in a Middle-Eastern Healthy Population Using 2nd and 3rd Generation PTH Assays

Background: The purpose of the current study is to determine PTH reference values in vitamin D replete Lebanese adults using a 2nd and 3rd generation of PTH assays, and to look at the factors that affect PTH variations. Methods: Fasting PTH was measured using 2nd and 3rd generation Diasorin PTH assays in 339 vitamin D replete healthy subjects aged 18 to 63 years (230 men and 109 women) who have normal calcium levels and an eGFR ≥ 60 ml/mn. 25(OH) vitamin D (25(OH)D) was measured using the Diasorin assay. Results: For the 2nd PTH generation, median (IQR) levels were 48.9 [34.9-66.0] pg/ml and its 2.5th-97.5th percentile values were 19.7-110.5 pg/ml for 25(OH)D values between 20 ng/ml and 30 ng/ml, and 19.7-110.7 pg/ml for 25(OH)D values ≥ 30 ng/ml. For the 3rd PTH generation the median (IQR) values were 23.9 [17.7-30.5] pg/ml and its 2.5th-97.5th percentile values were respectively 9.2 and 50.2 pg/ml for 25(OH)D values between 20 ng/ml and 30 ng/ml, and 8.4 and 45.4 pg/ml for 25(OH)D values ≥ 30 ng/ml. The median (IQR) serum 25(OH)D levels were 27.5 [23.8-32.7] ng/ml. 2nd and 3rd generation PTH values are strongly correlated (r=0.96, p value ˂0.0001), but poorly concordant (Lin’s concordance coefficient 0.365, 95% CI: 0.328-0.401) with observations beyond the 95% Bland-Altman limits of agreement. 2nd and 3rd generation PTH levels did not differ according to gender, and were significantly correlated with age but not with 25(OH)D and serum calcium levels. Conclusion: Lebanese adult healthy subjects have higher 2nd and 3rd generation PTH levels compared to the reference range provided by the manufacturer. The reference range was not influenced by changing 25(OH)D cut-off the clinical significance of the higher PTH levels in our population should be investigated.
DDoS Attacks, Detection Parameters and Mitigation in Cloud Environment

Cloud computing refers to providing on demand services and computing resources via Internet. The cloud environment has many security challenges among which DDoS attcks have maximum priority. Within Cloud Security issues being dominant for the private enterprises, the denial of service attacks are rated as the highest priority threat. This paper presents a review of DDoS attacks and parameters to detect attacks and mitigation mechanisms.
Survey Paper on Diagnosis of Breast Cancer Using Image Processing Techniques

Breast cancer is the oldest known type of cancer in humans. The oldest identification and definition of cancer was recorded in Egypt in around 1600 BC. Since then this disease has been researched and studied to avoid outcomes caused by it but still this disease is considered as one of the most deadliest diseases of all times, as deaths caused by breast cancer only in US in 2012 reached 40,000. In the modern medical science there are plenty of newly devised methodologies and techniques for the timely detection of breast cancer. Most of these techniques make use of highly advanced technologies such as medical image processing. This research study is an attempt to highlight the available breast cancer detection techniques based on image processing and provides an overview about the affordability, reliability and outcomes of each technique.
Assessment of food handler's compliance to personal hygiene practices in fast food outlets in Thohoyandou, South Africa

Food safety is becoming a key public health priority because a large number of people consume their meals outside their homes. As a result, they are exposed to food borne illnesses that originate from food stalls, restaurants and other food outlets. Hence the major objective of carrying out this research study was to assess food handler's adherence to personal hygiene practices in fast food outlets in Thohoyandou as stipulated in national food hygiene and regulations. The data was collected using participant observational checklist. Simple random sampling was used to select 122 food handlers as participants in the study. Data analysis involved descriptive statistics (frequencies and percentages). Result analysis was made based on the standards and the requirements prescribed by Regulation R962 of November 2012. The findings showed that food handlers observed personal hygiene by wearing clean uniforms, covering their heads with hair nets, and washed their hands, indicating that food handlers maintained accepted standards in terms of personal hygiene regulations. Regarding health surveillance practices majority of food handler were not medically examined regularly, however they reported illness to management when sick, but some prepared food when they had cough and open sores on their hands. The study recommends that strict adherence to Regulations R962 be enforced and adhered to in order to ensure and assure the preservation and maintenance of food safety.
The Effect of Septic Tank Locations on Borehole Water Quality in Port Harcourt, Nigeria

The effect of septic tank locations on borehole water quality in five locations in Port Harcourt metropolis of Rivers State, Nigeria, was investigated. The locations were Miles I and III, Old GRA, Rukpokwu and Ada George. Three boreholes and septic tanks were involve in each location. The distance between each borehole and septic tank was measured while water sample from each borehole was analysed for parameters such as appearance, taste, pH, electrical conductivity, temperature, salinity, and turbidity. Other parameters were total dissolved solid (TDS), phosphate, sulphate, nitrate, ammonium, chlorides, alkalinity, dissolved oxygen, bio-chemical oxygen demand, total heterotrophic bacteria (THB), total coliform bacteria (TCB) and faecal count bacteria (FCB). The results obtained from the various locations were compared with WHO drinking water quality standard. From the results, there was no problem with appearance and taste. However, the highest pH value was 4.4 from both Mile III and Ada George, with distance between borehole and septic tank of 6m and 9m respectively. The pH value is below that recommended by WHO (6.5-8.5), thus indicating that the water from all the locations, irrespective of distance between boreholes and septic tanks, is acidic. For Salinity, only water samples from Old GRA and Rukpokwu (0.1mg/l each) were outside WHO’s specified limit of 0.05mg/l, despite the varying distances between boreholes and septic tanks. Water samples from all the other locations were also within the recommended WHO’s limit for TDS, sulphate, nitrate and chloride. For total heterotrophic bacteria (THB), total coliform bacteria (TCB) and faecal count bacteria (FCB) only water samples from Ada George have values greater than that recommended by WHO. Water from Ada George, irrespective of distances between borehole and septic tank has the highest coliform contamination, thus rendering the water unsuitable for human consumption.
Renal Ureteral Obstruction and Alpha-smooth Muscle Actin (alpha-SMA) Research Literatures

Acute unilateral obstructive uropathy urology a unilateral block of urine flow through the ureter of 1 kidney, resulting in a backup of urine, distension of the renal pelvis and calyces, and hydronephrosis etiology kidney stone, trauma, stricture in children–of one ureter causes acute unilateral obstructive uropathy; slow, progressive blockage causes chronic unilateral obstructive uropathy; either may result in permanent damage and failure of one kidney and HTN, resulting in the so-called Goldblatt kidney, which is usually asymptomic–the remaining kidney usually has functional reserve. Ureteral obstruction results in renal fibrosis in part due to inflammatory injury. This article introduces recent research reports as references in the related studies. [Ma H, Young M, Yang Y. Renal Ureteral Obstruction and Alpha-smooth Muscle Actin (alpha-SMA) Research Literatures. Rep Opinion 2015;7(12):41-63]. (ISSN: 1553-9873). http://www.sciencepub. net/report. 5. doi:10.7537/marsroj071215.05.
A Structural Equation Modeling the Role of Social Norms in Tax Compliance: A Study from Turkey

The aim of the research is to examine the indirect and direct effects of social norms, general fairness and procedural fairness on tax compliance intentions in small and medium sized enterprises in the province of Bursa.The study group consists of 320 participants. 87.8% of participants were male and 44.7% participants were graduated secondary school. 64.7% participants were owner. We used Structural Equation Modeling for the data analysis. The results were X 2 /df=1.880; GFI=0.82; CFI=0.90; RMSEA=0.05; SRMR=0.08. The goodness of fit provided evidence that the hypothesized model was stable. All estimated path coefficients were significant. We found that general fairness directly affects procedural fairness; procedural fairness directly affects subjective norms. Subjective norms, injunctive norms and descriptive norms directly affect personal norms. Only personal norms directly affect compliance intentions.
STUDY OF HISTOPATHOLOGICAL

Anaemia is a potential hazardous hematological disorder that may occur in pregnancy. It is important risk factor for uteroplacental insufficiency and is associated with late abortions, prematurity, low birth weight and stillbirths. The present study aimed associated with maternal anaemia (mothers with Hb level < 11 g/dl) were fifty (50) and those collected from control mothers were fifty (50). All the deliveries were at full term (37 periods and with were done and these findings were compared. Statistical analysis was performed by using t comparing the mean values of fetal weights, placental weights and placenta anaemia group with those of control group. It was observed that the mean fetal weight of pregnancy with anaemia group was less than those of the control group. The mean placental weight in pregnancy with the anaemia group was more maternal anaemia group was higher than that of the control group. Histopathology study revealed decreased increase controls. We concluded that maternal anaemia resulted into big whereas placental morphological changes showed signs of chronic hypoxia and placental insufficiency.
MYCOBACTERIUM AVIUM SUBSP. PARATUBERCULOSIS INFECTION IN CATTLE: PATHOGENESIS AND DIAGNOSIS

Paratuberculosis or Johne's disease caused by Mycobacterium avium subsp. Paratuberculosis (MAP) is a chronic granulomatous enteric disease that affects all categories of ruminants including cattle, goats, camels and buffaloes. The infection is typically characterized by a long incubation period followed by loss of condition, a reduction in milk yield, oedema, anaemia, weight loss, chronic progressive and diarrhoea leading to cahexia. Currently here is no treatment and it invariably leads to the death of the affected animal. MAP is mostly acquired orally in cattle and other ruminants and often in young calves although intra-uterine transmission of MAP occurs. Control of the disease in ruminants is dependent on the early detection and culling of infected animals. The principal diagnostic tests for MAP infection in animals are individual or pooled faecal culture, ELISA and IFN-γ release from activated white cells in response to MAP antigens. Lately, PCR diagnostics have also been introduced. It has been suggested that this microorganism may be associated with Crohn's disease (CD) in humans. To eliminate paratuberculosis infection from cattle herds, early identification and elimination of MAP-shedders is a must. Rapid and cost-effective diagnosis methods of MAP remain a high priority task not only for animal breeders but also for the food production industry and for public health concern.
Induction of Acute Renal Failure to Study of Some Physiological and Histological Criteria in Rats Before and After Treatment with Eruca Sative Oil Extract of Leaves

Objective : the objective of the study was to test oil extract of Eruca sativa leaves by trying to treat acute renal failure that induced by injected Cisplatin intraperitoneally with 7.5 mg/kg of body weight (single dose) as animal model and measuring some predicate biomarkers and histopathological sections. Methods: the oil extract of Eruca sativa leaves was prepared by using petroleum ether according to the method of Stahl ,different concentration prepared by using dry gum method (4:2;1) 1000mg/kg,750kg/kg and 500mg/kg , acute renal failure induced in male of rats by injected Cisplatin intraperitoneally with 7.5 mg/kg of body weight (single dose ) functional common kidney biomarker was done blood urea nitrogen, serum creatinine and novel biomarker measured copeptin(CPP) , kidney injury molecule-1(KIM-1) and Neutrophils associated gelatinase lipocalin(NAGL) also histopathological sections done foe hematoxylin & eosin and trichome stain ( modified masson's). Result : there is significant increase of Serum creatinine(Scr.), and blood urea nitrogen(BUN) in cisplatin group when compared with control group, also indicate there is significant increase in serum biomarkers for kidney injury CPP , KIM-1, and NAGL when compared with control group. After the treatment with oil extract of Eruca sative leaves by different concentrations 1000 ,750 and 500 mg/kg all these Scr. , , BUN, CPP , KIM-1and NAGL were significantly decrease when compared with cisplatin group. Histopathological changes in kidneys were observed as show interstitial inflammation, tubular cellular swelling diffuse cellular swelling, tubular necrosis , mild inflammation and fibrosis in cisplatin group when compared with control group and after the treatment the damages were not found or minimize . Conclusion : The biomarkers CPP, KIM-1 and NAGL may be good predictive indicator of acute renal failure, plant extract may be has a highly effect for treating the renal failure and this was shown through the sections of the tissue in addition to biomarkers tests which reveal the induced acute renal failure groups showed highly response to treatment.
Zebrafish Parkinson’s Model: Rotenone decrease motility, Dopamine, and increase α-synuclein Aggregation and Apoptosis of Zebrafish Brain

Rotenone is a pesticide that is widely used to kill insects and nuisance fish in lakes. The mechanism of toxicity of rotenone is primarily mediated by its potent mitochondrial complex I inhibition. In this study, we examined the motility, dopamine, synuclein and apoptosis as hallmark of PD in rotenone-induced zebrafish (Danio rerio). We used adult zebrafish (8 months) and exposed to 5 g/L rotenone for 28 days. Motility observed for 5 minutes in each week. Measurement dopamine (DA) by ELISA, apoptosis by immunohistochemistry and -synuclein by immunohistochemistry and westernblotting of zebrafish brain. The results showed that rotenone significantly (p < 0.05) decreased motility start at day 14, decreased dopamine, increasing α-synuclein expression and aggregation that seems both of that leading to apoptosis of neuronal cells. Together, these data suggest that sub chronic exposure (28 days) of rotenone 5 μg/L caused Parkinsonism due to decreases dopamine level, locomotor activity, increasing α-synuclein expression and aggregation and apoptosis of dopaminergic neuron as well.
Relationship between Employees’s Participation and Their Organizational Commitment in Fars and Bushehr Regional Electric Company

The aim of this study was to examine the relationship between employees’ participation and their organizational commitment in Fars and Bushehr Regional Electric Company.Method: in a correlational study, 389 employees (340 men and 40 women) were selected via simple random sampling. Organizational commitment scale, a researcher–made scale for employee’s participation and a number of questions for acquiring demographic information were administered to the participants. Data analysing methods included descriptive statistics and stepwise multiple regression. Results showed that employee’s participation was related positively to their organizational commitment. Level of education had negative relationship with emotional and normative commitment. Work experience had negative relationship with normative commitment. None of the independent variables had significant relationship with continuance commitment and employee’s participation can enhance their organizational commitment.
A Prospective Study on Prevalence of Thyroid Disorders in Hepatitis C Virus Infected Patients in a Tertiary Care Teaching Hospital

Background: Hepatitis C virus (HCV) infection has been associated with thyroid abnormalities. Therefore this study was conducted to determine the association of thyroid disorders with chronic hepatitis C virus infection in patients who are not getting any antiviral treatment. Methods: Sixty-five patients without pre-existing thyroid abnormality having positive Hepatitis C Virus (HCV) infection (confirmed on PCR) and not willing for getting anti-viral treatment (interferon) were included in our study. Blood samples from 65 patients were collected at base line, 04 months, 08 months and at 12 months. The level of thyroid stimulating hormone (TSH) and thyroid antibodies was measured in these samples. Results: Nine patients (13.84%) developed thyroid disorder during the study period. Female patients (66.66%) mostly affected than males (33.33%). Among n=9 affected cases, 66.66% developed hyperthyroidism, 22.22% developed hypothyroidism and 11.11% developed positive thyroid antibody. Conclusion: A close association of thyroid disorder and chronic HCV infection is noted in the study population.
Myoglobin Chemistry and Modifications that Influence (Color and) Color Stability

Myoglobin is a heme-containing protein that participates in aerobic metabolism in antemortem muscle by storing and/or delivering oxygen. Several scholarly reviews have been devoted to the chemical characterization of myoglobin and its effect on meat color (Faustman and Cassens, 1990; Renerre, 2000; Mancini and Hunt, 2005). this review will re-confirm the criticality of heme properties as they relate to meat color and color stability but also remind the reader that myoglobin’s apoprotein, within which heme is located, plays an important role in the extent to which heme-related reactions may occur (Wang, 1962).
"There's Always Hope": Content, Participants, and Dynamics of Discussions in a Lung Cancer Internet Support Group

[last month] I joined this virtual family. After intro, I requested the experience of people as to what if anything to do next after successful sleeve lobectomy on right lung. The overwhelming response was to do something beyond just close monitoring. I am to begin some empirical chemo treatments.I am thankful for your pushing me to do something. Also I find that I am hooked to reading the [list’s] mail every day. Let us keep up the good work Gratefully in His Hands, Charles.a
On the Determinants of Outward Foreign Direct Investment: Empirical Evidences from Thailand

Foreign direct investment (FDI) has played an important role in Thailand’s economic growth and development in the Asia-Pacific area. Since 1988-1990, Thailand has been a major destination for FDI, but rapid increasing trend in outward FDI was not seen until 2003. Empirical results of this study show that major determinants such as Thailand’s opennessand bilateral trade agreements have positive and statistically significant effects on Thailand’s outward FDI. On the other hand, exchange rates and global financial crisis have negative and statistically significant effects. Hopefully, the empirical results provide investors and policymakers some implications to select the appropriate investment decisions.
The time has come to pull renal cancer’s sweet tooth

The metabolic theory of cancer is based on cancer’s unique suppression of mitochondrial glucose oxidation and upregulation of cytosolic glycolysis, first identified by Otto Warburg nearly 100 years ago (1). This “Warburg effect” has been shown to be driven by numerous mechanisms including growth factor signalling, oncogene expression, metabolic enzyme mutation and regulation of factors that control mitochondrial homeostasis (2).
Clinical and Paraclinical Profile of Patients in First Nephrology Consultation at the Aristide Le Dantec University Hospital Center (ALD-UHC) About 542 Cases

Chronic kidney disease (CKD) is a public health problem worldwide because of its increasing frequency, severity, and high cost of management [1,2]. The late discovery of CKD is partly related to its asymptomatic nature, lack of training of practitioners, and lack of awareness of the population. In patients with CKD, the earlier the nephrologist is consulted (before starting renal replacement therapy) the lower the morbidity and mortality due to better preparation for renal replacement therapy, the management of the complications of CKD such as anemia and malnutrition as well as the introduction of a conservative treatment. CKD is still often discovered at a late stage even in developed countries. In Canada, 52% of CKD cases are in stage IV at the first nephrology consultation [3]. In sub-Saharan Africa, more than two-thirds of CKD cases are encountered for the first time at stage V [4]. Primary prevention seems to be the best way to reduce the incidence of CKD in developing countries such as Senegal. It is in this context that we undertook this work with the aims of describing the epidemiological, clinical, and paraclinical profile of the patients referred to their first nephrology consultation. Introduction: Late recourse to nephrology consultation remains a topical issue which concerns both developed and developing countries such that a majority of the patients are seen to be at an advanced stage of chronic kidney diseases. The aim of this study is to assess the clinical and paraclinical profile of patients referred for primary nephrological consultation. Abstract
Masked Advanced Encryption Standard for Area Optimization

The Advanced Encryption Standard (AES) is a symmetric-key block cipher published by the National Institute of Standards and Technology (NIST)[1]. In order to protect data, a high throughput masked Advanced Encryption Standard (AES) engine is used. The masked AES engine uses the unrolling technique which requires extremely large field programmable gate array (FPGA) resources. The area for a masked AES with an unrolled structure is optimized. The mapping of operations from GF(2) to GF(2) as much as possible in order to optimize area. The number of mapping is reduced [GF(2) to GF(2)] and inverse mapping [GF(2) to GF(2)] operations of the masked SubBytes step from ten to one. In order to be compatible, the masked MixColumns, masked AddRoundKey, and masked ShiftRows including the redundant masking values are carried over GF(2). By moving, mapping and inverse mapping outside the masked AES’s round function, area can be reduced by 20%.
Survey of the effect web design aspect on effectiveness of E-marketing by E-trust mediator

This study examined the effect of web design aspect on effectiveness of E-marketing by e-trust mediator in selected branches of Bank Melli in the center of the khorasan Razavi Province. The research method was descriptive-survey in year of 2013. The statistical population includes customers of Bank Melli branches of Mashhad which have used Bank Melli websites for banking services at least one time. For selection of statistical sample Morgan's table in unlimited population (n=10,000) were used. From the 107 branches based on ratings given by the supervisor classified random sampling method was used. According to Morgan's table and 19 representative branches, in order to increase the credibility of the study, 400 questionnaires were distributed and 336 questionnaires were receive and analyzed. To test the research hypothesis probability value (T-value) were used resulting in fitness of the model in parameters significance mode through structural modeling by use of Smart PLS software. In statistical analysis using path analysis test, the results showed that the Web site design has a significant effect on E-marketing effectiveness. The design aspect of website does not have significant effect on e-trust. E-trust has a significant effect on the effectiveness of E-marketing. there is not a significant relationship between website design and E-marketing effectiveness through E-trust.