Miracle-dz/UniFAR-FTUs huggingface dataset:
Costus Afer Ameliorates Lead-Induced Reproductive Alterations in the Pituitary-Testicular Axis: Histopathological and Biochemical Studies

Lead is a multiple organ toxicant and an oxidative-stress inducer. The present study investigates the protective effect of Costus afer ethanol leaf extract on lead- induced reproductive damages in male Wistar rats. Twenty adult male Wistar rats were weighed and separated into four groups of five rats each. Groups 1 served as control, group two received 1000mg/kg of Lead, and while groups three and four received 400mg/kg and 800mg/ kg of CAEE for 12 days. The reproductive and antioxidant parameters obtained from the result served as scientific evidence in the study. The result showed non-significant increase in testosterone level in groups treated with CAEE when compared with group treated with lead only. Significant increases were observed in the antioxidant enzymes in the groups treated with CAEE in both serum and testicular antioxidant assessment (p<0.05). Mild restoration of the architecture of the pituitary gland were observed in the group treated with high dose of CAEE when compare with lead toxic group. Insignificant alterations were observed in the section of the testes in all the groups. The treatment with CAEE exhibited dose-dependent significant changes in testicular and serum oxidative stress changes induced by lead. Ethanol leaf extract of Costus afer may be protective against lead induced testicular and pituitary gland damage.
Etude de l'influence des particules sur la turbulence à partir de simulations directes et de simulations des grandes échelles d'écoulements diphasiques gaz solides homogènes isotropes stationnaires

L'interaction reciproque entre une turbulence fluide et des inclusions dispersees a ete etudiee a l'aide de simulations numeriques directes (DNS) en turbulence homogene isotrope stationnaires forcee. Le temps de relaxation des particules va de l'echelle turbulente de Kolmogorov a celle eulerienne et la charge de 0 a 1. L'analyse a ete effectuee dans le cadre du modele eulerien complete de l'approche lagrangienne developpes au Laboratoire National d'Hydraulique et etendue au couplage inverse et aux effets de Reynolds. On trouve que les particules dissipent en moyenne de l'energie turbulente. Les spectres de taux d'echange d'energie entre phases montrent que les particules entrainent le fluide sur les grands nombres d'onde, expliquant la croissance relative constatee des petites echelles turbulentes. Une analyse spectrale revele que le mecanisme physique responsable est celui du transfert de covariance fluide-particules par la turbulence. Concernant la modelisation, la dependance en Reynolds et la contribution directe de la charge s'averent essentielles pour bien predire les moments de la phase dispersee. Une etude prospective pour des applications pratiques par simulations des grandes echelles (LES) a donne les resultats suivants : la LES peut s'utiliser pour les ecoulements diphasiques totalement couples a condition d'employer le modele dynamique mixte de sous-maille et de prendre des particules de temps de relaxation superieur a celui de coupure : le couplage inverse dependrait davantage de la position de ce temps de relaxation par rapport au temps eulerien que par rapport a celui de Kolmogorov.
Parameters of Peat Formation in the Mississippi Delta (Holocene).

The Mississippi Delta is located in a subtropical and moderately humid climate. Six major Holocene deltaic complexes developed, each with a life span of about 1500 years (Coleman and Gagliano, 1964; Frazier, 1967; Kolb and Van Lopik, 1958). Peats accumulate over abandoned delta lobes, in large-scale interdistributary basins, in abandoned channels, and as detrital peats nearshore. This dissertation discusses the first three types. Emphasis is on Barataria Basin, a large-scale interdistributary basin, located between levees of the Lafourche and St. Bernard/Plaquemine delta complexes. A characteristic 6 m thick set of lithostratigraphic units constitutes basin-fill sediments. These units are: open bay, restricted basin, each blanketed by massive organic muds (abandonment phases), natural levee, basin drainage channel, lacustrine sediments, crevasses, and organic sediments, ranging from various types of organic-poor beds to organic-rich beds and peats. Organic-rich beds occur in three phases, each representing an accumulating period that was interrupted by subsidence and the influx of detrital clastics from renewed nearby fluvio-deltaic sedimentation.
Risk Committee and Risk Disclosure Quality: Evidence from Listed Insurance Firms in Nigeria

Objective –This study investigated the impact of risk committee characteristics on the risk disclosure quality (RDQ) of listed insurance firms in Nigeria from 2011-2021.Design/Methodology –Data for the research was generated from the annual reports and financial statements of seventeen listed insurance firms sampled out of a population of twenty-one. The study employed descriptive summary statistics, correlation analysis, regression analysis and factor analysis to analyze the data gathered.Results –Using factor analysis, it was found that Risk Disclosure Quantity (RDQUANT) has the highest eigenvalue, making it the composite quality of the risk disclosure of listed insurance firms and denoting that the RDQ of insurance firms is best measured by the RDQUANT. Using GLS regression, it was found that Risk Committee Size (RCS) and Risk Committee Meeting (RCM) have a significant positive impact on the RDQ of Listed Insurance firms in Nigeria. Contrary, Risk Committee Executive Presence (RCEXP) has an insignificant negative impact on the RDQ of the listed insurance firms.Research limitations/implications –This result influences the efforts of regulatory authorities in their attempt to develop resilient corporate governance codes that guarantee qualitative risk disclosures. The study recommends that regulatory authorities in the Nigerian insurance industry should mandate the establishment of large risk committees and set higher thresholds for committee meetings over and above the traditional quarterly meeting. The risk committee should be composed of a lower number of executive directors.Novelty/Originality –The originality of this study lies in the usage of factor analysis to determine the best measure of risk disclosure quality in Nigeria. In addition, this is the first study of its kind to determine the impact of risk committee attributes on risk disclosure quality in the Nigerian Insurance industry.
The impact of technology-enabled disinformation towards the victims of sexual objectification as portrayed in Photocopier (2021) movie

Technology abuse is rising in an age where communication technology is used daily. This can happen through social platforms, media, and even represented in streaming platforms. Some people can be affected by technology abuse, including sexual objectification victims. This study investigates the impact of disinformation represented in the movie, Photocopier (2021). Therefore, it aims to find the impact of technology-enabled disinformation and how society plays a role in the digital era concerning a sexual objectification case as portrayed in Photocopier (2021) movie. The information is gathered from dialogues and scenes in the movie and then analyzed using cascading theory and sexual objectification theory. The study used a qualitative approach to achieve its goals. The findings suggest that technology has a negative impact on sexual objectification victims due to the rapid transmission of important records, which leads to victim blaming. Furthermore, society purposefully disseminates confidential sexual objectification documents without sympathizing with the victims. Therefore, it can be said that disinformation caused by technological advancement happens and impacts some people negatively. Society must be aware and play a more supporting role, thus resulting in a sustainable society living with technology for more beneficial effect.
Utilization of polymerase chain reaction technology in the detection of solid tumors

Representing a busy flow cytometry laboratory with an annual workload of approximately 1400 acute leukemia and malignant lymphoma cases, we read the article by Naughton et al. with considerable interest. The authors concluded that “flow cytometry of bone marrow aspirates has a limited role in the routine staging and follow-up of patients with an established diagnosis of [non-Hodgkin’s lymphoma] NHL. ” However, this conclusion must be challenged because a number of methodologic flaws and inadequacies in the process, analysis, and interpretation are evident in this study. The authors used Ficoll-Paque (Pharmacia Biotech, Piscataway, NJ) processed specimens rather than recommended erythrocyte lysis. Ficoll-Paque centrifugation of bone marrow aspirates is known to result in the selective loss of some cell populations. This phenomenon is related to the fact that neoplastic lymphoid cells may have a different buoyant density from normal lymphocytes and may not be found where anticipated in the gradient. The authors, possibly unknowingly, thus may have reduced the number of potentially analyzable malignant lymphoid cells in their samples, which may explain a portion of their staged cases with a negative flow result. Single color flow cytometry was used on 81 specimens and two color flow cytometry on the remaining 192 specimens. It currently is widely accepted that even two color flow cytometric analysis is inadequate for an appropriate characterization of hematologic neoplasia and virtually precludes an accurate assessment of minimal residual disease. Five parameter analysis including forward and side scatters accompanied by at least three color analysis should constitute the minimal standard for immunophenotypic analysis of lymphoproliferative diseases, with a sensitivity approaching detection of one malignant cell in 100,000 reactive lymphocytes. The authors make no mention of attempted blockade of cellular Fc receptors. This step is to eliminate the common error of spuriously detecting light chain restriction while in fact observing a phenomenon of passive cytophilic immunoglobulin absorbed onto nonlymphoid B cells. In contrast, failed blockade of Fc receptors on lymphoid cells may lead to false-negative results. Apparently no specific gating strategies were utilized. For increased sensitivity, the routine use of a B-cell gate (CD19 1 lineage gate) is recommended. In addition, application of other unique markers known to be present on subsets of non-Hodgkin’s lymphoma (NHL) and chronic leukemia cells provides added resolution for the assessment of bone marrow involvement. Unique gating strategies should differ based on the type of NHL present at diagnosis (i.e., follicular lymphoma (CD191/CD101), small lymphocytic leukemia/ lymphoma and mantle cell lymphoma (CD191/CD51), etc). This 240
CRNet: Context-guided Reasoning Network for Detecting Hard Objects

Recent studies have shown impressive performance in object detection. However, most current detectors only explore the appearance feature to locate and classify objects but disregard or underestimate the valuable contextual information in the image, which limits the detection performance for those hard objects, such as small objects, occluded objects, blurred objects, etc. In this article, we instead seek to build a novel context modeling framework and conduct more effective context reasoning for object detection. Specifically, we design a Context-guided Reasoning Network (CRNet) to explore the relationships between objects and use easy detected objects to help understand hard ones. In our CRNet, an image is modeled as a graph and local features of objects are viewed as nodes of the graph to learn the relationships between objects. By passing contextual information in the built graph, the features of hard objects can be updated to discriminative features. To this end, we first develop a cascaded center prediction module built upon CenterNet to produce a set of high-quality proposals viewed as nodes of the graph. In addition, to maximize the value of global context information, we present a multi-granularity feature fusion network to encode the whole scene information which is also viewed as nodes of the graph. Then, the spatial and semantic relationships between objects are learned to initialize edges of the graph. Finally, context reasoning is conducted to update the node states iteratively. Extensive experiments are conducted on MS COCO and Pascal VOC to demonstrate the effectiveness of the proposed CRNet. Experimental results show that the proposed CRNet greatly improves the detection performance over existing context-based detectors, and it is comparable with state-of-the-art detectors.
Resolved simulations of sedimenting suspensions of spheres

Several results on sedimenting equal spheres obtained by resolved simulations with the Physalis method are presented. The volume fraction ranges from 8.7% to 34.9% and the particle Galilei number from 49.7 to 99.4. The results shown concern particle collisions, diffusivities, the mean free path, the particle pair distribution function, and other features. It is found that many qualitative trends found in earlier studies continue to hold in the parameter range investigated here as well. The analysis of collisions reveals that particles interact prevalently via their flow fields rather than by direct contacts. A tendency toward particle clustering is demonstrated. The time evolution of the shape and size of particle tetrads is examined.
Yukon Delta coastal processes study

Much of the Yukon delta is underlain by the onland extension of the Nunivak Arch; this would seem to exclude most of the region for serious consideration for exploration. Nevertheless, the Quaternary faults and volcanoes which characterize the zone constitute serious geologic constraints on the selection of transportation corridors. The discontinuous permafrost and the complex hydrology of the delta further complicate the location of such corridors, as well as making it difficult to predict the effects of oil spills. The selection of shoreline sites must take into account the present coastal stability, including the possibility of erosion associated with major storm surges, even in an area of long-term progradation. In addition, the effects of shorefast ice for over half of the year must be considered. The siting of offshore facilities must take into account the extent and variability of shorefast ice, the possibility of offshore permafrost, and the possible effects of altering offshore bathymetry in changing coastal stability. In addition, the effects of possible oil spills must take into account not only the dominant northward drift of the water and sediments, but also the local and seasonal variability of current patterns.
Study of aerotolerant Campylobacter Jejuni in broiler production process

Campylobacter jejuni is the leading cause of human gastroenteritis worldwide. Although they are microaerophile and sensitive to oxygen, aerotolerant C. jejuni has been reported in many countries. Currently, limited information on aerotolerant C. jejuni in Thailand has been reported. Therefore, the objectives of this study were 1) to examine the occurrence of aerotolerant C. jejuni in farms, slaughterhouses and retail markets and compare the level of aerotolerant strain between different sample types at the farm (i.e., cloacal swabs VS manures) and slaughterhouse level (i.e., cecal contents VS carcass rinses) and 2) to identify common genotypes of aerotolerant and aerosensitive C. jejuni strains in each poultry production stage. A total of 275 C. jejuni strains isolated from cloacal swabs, manures, cecal contents, carcass rinses and raw chicken products were�tested for aerotolerance by aerobic shaking at 150 rpm under aerobic condition at 42? C for 24 hours. Representatives of C. jejuni isolates were primarily genotyped by flaA SVR sequencing technique and further subtyped by MLST. The highest number of aerotolerant C. jejuni isolates were found at the slaughterhouse stage (56.0%), followed by the retail market stage (51.0%) and the farm stage (41.3%). The level of aerotolerant C. jejuni strain between different sample types at the farm and slaughterhouse level were not significantly different. Hyper-aerotolerant strain was not detected in this study as no bacterial strains survived 24 h of aerobic shaking. The longest viability of C. jejuni strains under aerobic culture was 18 h with the viable counts of 2.59 log CFU/ml, 3.53 log CFU/ml and 3.06 log CFU/ml at the farms, slaughterhouses and retail markets, respectively. Forty-one flaA SVR allele types and 17 sequence types (STs) were identified among aerotolerant and aerosensitive C. jejuni strains. The predominant allele types in aerosensitive and aerotolerant strains was flaA SVR allele number 142 and 783, respectively. Mostly, genetic similarity was found in isolates from farms and slaughterhouses. For MLST, the results revealed that the most frequently detected ST�in aerosensitive strains was ST-460, while ST-1232 was predominant in aerotolerant strains. The main clonal complexes (CCs) observed in this study were CC- 353, followed by CC-45. Most of the STs (e.g., ST-1075 and 1232) found in this study were previously identified in chickens and gastroenteritis patients in Thailand, which highlight the significance of broilers as one of the most important sources of human campylobacteriosis. Our findings suggested that the reduction of Campylobacter contamination in the final products by implementation of good hygienic practices and strict biosecurity in poultry production steps is essential and would help decrease the transmission of Campylobacter to human, which eventually reduce the number of foodborne campylobacteriosis cases. ��
Perceived Social Support, Depressive Symptoms, Self-Compassion, and Mobile Phone Addiction: A Moderated Mediation Analysis

Objective: The primary objective of this study is to investigate the relationships between perceived social support and mobile phone addiction, as well as the mediating effect of depressive symptoms and the moderating effect of self-compassion. Methods: A total of 874 college students completed questionnaires, including the perceived social support scale, depression–anxiety–stress scale, mobile phone addiction index, and the short form of the self-compassion scale. The participants included 202 males and 672 females, with an average age of 19.54 (SD = 2.16). Results: A moderated mediation analysis was conducted. The results revealed that perceived social support fully mediated the negative relationship between perceived social support and mobile phone addiction. Self-compassion attenuated the mediating effects. Conclusions: The present study indicated that insufficient perceived social support may increase the risk of mobile phone addiction among college students because of the impact of depressive symptoms. However, self-compassion could buffer this adverse effect.
Comparison of the accuracy of implant position using different drilling system for static computer-assisted implant surgery: in vitro study

Purpose: The aim of this�in vitro�study was to compare the accuracy of implant placement among five drilling systems of sCAIS. Materials and Methods: Twenty-five 3D printed models with two edentulous bilateral premolar spaces were allocated to five different drilling systems: group A: sleeve-in-sleeve, group B: sleeve-in-sleeve with self-locking, group C: mounted sleeve-on-drill, group D: integrated sleeve-on-drill with metal sleeve in the guide, group E: integrated sleeve-on-drill without metal sleeve. All implants were digitally planned and 10 implants placed with sCAIS in each group. Postoperative 3D deviation of actual vs planned position was measured by means of platform, apex and angular deviation. Data was analyzed using Kruskal-Wallis test (P�? .05). Pairwise comparisons were tested with Dunn's test. Results: The overall platform deviation ranged from 0.42? 0.12 mm (group B) to 1.18? 0.19 mm (group C). The overall apex deviation ranged from 0.76? 0.22 mm (group B) to 1.95? 0.48 mm (group D). The overall angular deviation ranged from 2.50? 0.89 degrees (group B) to 5.30? 1.04 degrees (group E). Group A and B showed significantly less angular deviation than groups D and E (P�< .05). There was no statistically significant differences in all parameters between group A and B, as well as between group D and E (P�> .05). Conclusions: Significant differences were found with regards to accuracy among the five sCAIS systems tested, suggesting that the drilling protocol, the devices used and the design principles of the guides could influence the accuracy of implant placement.
Structure profonde de la marge nord-Gascogne et du Bassin armoricain

La formation et l'evolution de la Marge continentale passive Nord Gascogne et du Bassin Armoricain sont fortement liees a l'ouverture du golfe de Gascogne et a la formation des Pyrenees. L'etude des structures tectono-sedimentaires, calees aux forages profonds DSDP et petroliers, ainsi que l'etude de leurs prolongements dans les domaines emerges adjacents (Bassin de Parentis et les bassins de la Manche), ont permis de montrer l'evolution spatio-temporelle de la couverture sedimentaire. Un polyphasage tectonique lors du rifting et deux phases compressives pyreneennes ont ete identifies. Des evenements tectono-sedimentaires catastrophiques auraient affectes la marge a la fin du rifting. Le Bassin Armoricain serait un bassin sedimentaire jeune, ayant toutes les caracteristiques structurales d'une zone de Transition Ocean/Continent effondree a la fin du rifting ou lors de l'initiation de l'accretion oceanique. L'etude des structures crustales a permis de connaitre la geometrie de la marge : la distance domaine oceanique/domaine continental non-aminci est constante le long de la marge ; l'amincissement crustal s'effectue exclusivement sous l'etroite pente continentale, inferieure a 50 km de large ; les blocs bascules, situes au pied de la pente, ont un role mineur dans les processus d'amincissement crustal. Les modeles geodynamiques actuels d'une marge passive n'expliquent pas la geometrie de la Marge Nord Gascogne. Or cette geometrie, similaire a celle du Bassin de Parentis, n'est pas atypique ; nous pensons que l'amincissement est induit par d'autre processus geodynamique que l'extension pure.
Polyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy, and skin changes (POEMS) syndrome.

purplish discoloration, and the remainder of his skin had a bronze appearance. laboratory data revealed the following abnormalities: hematocrit 30.2% (range 40%–52%), serum creatinine 1.6 mg/dl (range 0.5–1.4 mg/dl), blood urea nitrogen 30 mg/dl (range 7–21 mg/dl), calcium 7.9 mg/dl (range 8.9–10.4 mg/dl), and albumin 3 units/l (range 3.5–4.8 units/l). Thyroid function test revealed a thyroid stimulating hormone of 10.97 units/ml (range 0.4–4.5 units/ml) and free T4 of 0.5 ng/dl (range 0.8–1.5 ng/dl). A vascular endothelial growth factor (vEgF) level of 3,010 pg/ml (range 31–86 pg/ml) was elevated. The hepatitis panel was negative. A computed tomography scan of the abdomen revealed hepatospleno- megaly and ascites. Bone marrow aspiration and biopsy revealed 3% plasma cells without clonality. serum protein electrophoresis revealed an immunoglobulin-A l (igA l) pro- tein but no quantifiable monoclonal protein. X-ray bone survey showed no lytic lesions. An echocardiogram showed an ejection