Miracle-dz/UniFAR-FTUs huggingface dataset:
for Transposase‑Accessible Chromatin‑sequencing and chromatin immunoprecipitation‑sequencing (ChIP‑seq)

PVRL4 (or nectin‑4) is a promising therapeutic target since its upregulated expression is found in a wide range of human cancer types. Enfortumab vedotin, an antibody‑drug conjugate targeting PVRL4, is clinically used for the treatment of urothelial bladder cancer. In addition, rMV‑SLAMblind, a genetically engineered oncolytic measles virus, can infect cancer cells and induce apoptosis through interaction with PVRL4. Although PVRL4 transcript levels are elevated in breast, lung and ovarian cancer, the mechanisms of its upregu‑ lation have not yet been uncovered. To clarify the regulatory mechanisms of elevated PVRL4 expression in breast cancer cells, Assay
A Hybrid Double Encryption Approach for Enhanced Cloud Data Security in Post-Quantum Cryptography

—Quantum computers and research on quantum computers are increasing due to the efficiency and speed required for critical applications. This scenario also kindles the vitality of data protection needed against threats from quantum computers. Research in post-quantum threats is very minimal so far, but it is much needed to protect the enormous data stored in the cloud for healthcare, governmental, or any crucial data. This research work presents an advanced hybrid double encryption approach for cloud data security based on Post-Quantum Cryptography (PQC) to ensure the restriction of unauthorized access. The suggested approach combines the benefits of the NTRU encryption and AES encryption algorithms and works in hybrid mode, offering strong security while resolving issues with real-time performance and cost-efficiency. A streamlined key management system is set together to improve real-time processing, significantly reducing encryption and decryption delay times. Moreover, NTRU Encrypt dynamic parameter selection, which adapts security parameters based on data sensitivity, maintains accurate information and security. In addition to addressing real-time performance and data security, an innovative development in this method is known as Quantum-Adaptive Stream Flow Encryption (QASFE), which enables secure data sharing and collaborative working within a quantum-resistant framework. This innovative feature enhances data accessibility while maintaining the highest level of security. In the era of post-quantum cryptography, our multifactor authentication technique, integrating double encryption and QASFE, is a proactive and flexible solution for securing cloud data, and protecting data security and privacy against emerging threats.
Survey of Aflatoxin Contamination in Ethiopia

Background: Aflatoxins are high(v toxic, hepatocarcinogenic, secondary metabolites of Aspergillus species produced in most agricultural commodities stored at inappropriate temperatures and water activities. The aim of the present paper was to analyse the levels and frequency of aflatoxin contamination in samples of most commonly consumed agricultural commodities collectedfrom various regions of the country. Methods: A total of 595 food samples collected from Southern Peoples Nations and Nationalities, Oromia and Harari Regional States were collected and screened for aflatoxin contamination. Commodities sampled included barley, wheat, maize, millet, sorghum, tef, pepper, peanut, broad beans and dry peas. Aflatoxins BJ and G J were the only mycotoxins detected in the food samples. Results: Aflatoxin B, was the predominant form, the incidence of samples containing it was 30% and then accompanied by aflatoxinG b 6%. The highest levels of aflatoxin B, was observed in peanut and sorghum samples (738 and 692f.J{Jkg- 1, respectively). The highest level of aflatoxin G 1 found was 201/1 gkg-l. Groundnut, sorghum and millet samples have been identified as high-risk commodities based on the incidence rate of aflatoxin contamination. Levels of total aflatoxin greater than 20 f.J{Jkg- 1, were most frequently encountered in all aflatoxin positive samples of corn, sorghum, wheat, red pepper and peanut followed by barley (17%) and teff (13%). Conclusion: The presence of aflatoxins in commonly consumedfoods emphasize a public health concern and the need to develop mycotoxin prevention and control strategies in Ethiopia.
Biogenic approach for synthesis of ZnO/NiO Nanocomposites as a highly e�cient photocatalyst and evaluation of their biological properties

Mixed metal oxide-based nanocomposites (NCs) had remained broadly used for photo catalysis-facilitated elimination of harmful substances from the aquatic ecosystem. Now a days searching for an improved photo catalyst looks plentiful metal oxide-based materials take began out of studies. In present works concerning the use of ZnO/NiO NCs as photocatalytic treatment of wastewater utilizing oxides of metals as photo catalysts has merged a subject of major concern. The way of coupling with other semiconductors for improved photo degradation in the presence of UV-visible light. NCs were mainly characterized by XRD, FT-IR, UV-DRS, morphological studies such as SEM and TEM, elemental composition by EDAX that all a�rmed the effective synthesis of NCs. For instance, ZnO/NiONCs having a bandgap of about 3.11eV achieved an outstanding degradation activity toward 100% photo degradation of methylene blue (MB) within a short period of time. Further, prepared ZnO/NiO NCs have excellent antibacterial activity against both Gram negative and Gram-positive bacteria. This behavior is primarily caused by the accumulation of ZnO/NiO NCs on the bacteria’s surface, which results in cytotoxic bacteria and a relatively increased ZnO, resulting in cell death. Also ZnO/NiO NCs exhibit essential harmless effects on human red blood cells and their intervention with the action of the clotting on both PPP and PRP in human erythrocytes. As an outcome, the studies have shown that Phyllanthus Niruri (L) mediated Green Synthesis by combustion methods performs well as a good capping agent to synthesize ZnO/NiO NCs with important multi-disciplinary applications.
Comparative Analysis of Banking Financial Performance Before and After Implementation of Financial Technology (FinTech) Case Study on BUMN Banking Period 2012–2021

Theaimtobeachievedbyholdingthisresearchistodeterminethecom-parison of ﬁnancial performance after the implementation of Fintech in BUMN bankingfortheperiod2012–2021.Thedatausedinthisresearchissecondarydata. Thesamplingtechniqueusedwasthepurposivesamplingmethod.Theanalysisof thisstudyusedthenormalitytestandtheaveragecomparativetest.Thevariables usedtomeasureﬁnancialperformanceinthisstudyareLDR,NPL,ROA,and BOPO. Inthecomparativetestbeforeandaftertheimplementationofﬁntechfor BankBRIthevariablesofNPL,ROA,andBOPOshowedtheresultsofsigvalue < 0.05 so there was a signiﬁcant difference, but in the variable of LDR the sig value > 0.05 so there was no signiﬁcant difference. For Bank BNI, the variable of ROA show sig values < 0.05 so there was a signiﬁcant difference, but the variables of LDR, NPL, and BOPO shows a sig value > 0.05 so there was no signiﬁcant difference. For Bank Mandiri, all variables show a sig value > 0.05 so there was no signiﬁcant difference. For Bank BTN, the variables of ROA and BOPO show a sig value < 0.05 so there was a signiﬁcant difference, while the variables of LDR and NPL show a sig value > 0.05 so there was no signiﬁcant difference. This study reafﬁrms the importance of applying Fintech. BUMN banking is expected to maximize the use of ﬁntech services in transaction activities because ﬁntech can improve the image of banking names with ease and sophistication. That way the banking ﬁnancial performance will run smoothly, to increase proﬁtability.
The Role of Trans-Generational Financial Knowledge and Self-Reported Financial Literacy on Borrowing Practices and Debt Accumulation of College Students

This paper studies the effects of trans-generational financial knowledge, self-reported financial knowledge, academic performance, and overall financial literacy on financial management practices, using a sample of 380 college students. Exploratory estimates using a series of ordered Probit models indicate that academic status and self-reported overconfidence on financial knowledge relate positively to the amount of debt a student carries. More interesting, our estimates provide strong support to the hypothesis that a trans-generational financial knowledge effect from parents to students plays a major role in reducing the amount of financial burden students assume. The trans-generational effect provides robust results, both in the form of student loans and credit card balance. In addition, students that maintain a good credit card history, as reflected by high repayment rates, are more likely to hold lower debt amounts than otherwise. A high debt level implies that students are living beyond their means and consequently developing unhealthy financial management practices. Our empirical estimates also find the presence of a strong overconfidence effect, as reflected by unrealistically high self-reported financial knowledge, leading students to an incorrect decision making process in favor to holding more debt. We argue that lack of personal financial literacy and easy access to credit are at the core of high debt accumulation.
High-Throughput Digital Imaging Analysis Of Historical Wheat Cultivars From Pakistan

Wheat is the most signi�cant cultivated crop in Pakistan, ranking �rst in terms of acreage and production among all cereals. Wheat grain morphology has been harvested and manipulated since the dawn of agriculture, and it remains a major breeding focus today. To establish, genetic basis of phenotypic variation in wheat grain morphology, the current research was conducted to develop a phenotyping method based on digital imaging to capture the grain morphology in bread wheat cultivars of Pakistan and to characterize variation in grain morphology in Pakistani wheat cultivars and their association with TaCWi genes. In this research 64 wheat cultivars were analysed by digital imaging approach. The images were captured using a �atbed scanner with a transparency adapter, and the imaging software image J 1.27 was used for analysis. The cultivars used in this study showed larger variation in grain morphology in more than �fteen descriptors. Measured dimensions included grain area, perimeters, height, width, circularity and solidity. Minimum grain area was showed by the T9 and maximum grain area was shown by the Pirsabak-2013, minimum grain perimeter was showed by the T9 and maximum grain perimeter was showed by the Barsat. Similarly, maximum grain area was exhibited by the Markaz-2019 and minimum grain area was shown by the C-271. Maximum grain perimeter was showed by the PARI-73 and minimum grain perimeter was showed by the C-271 respectively, under well-watered (WW) conditions. The coe�cient of determination was also higher indicating the reliability and consistency of digital imaging method. Digital imaging allowed many aspects of development, functions, traits and health to be monitored and traced in ways previously unattainable. Our results are encouraging that large image data sets of grains can be processed by high throughput and accurate manner.
Effect of Denture Cleanser on the Physico-Mechanical Properties of Injection-Molded Thermoplastic Polyamides Denture Base Material: A preliminary Study

Objectives This study aimed to assess the color stability, surface roughness, and flexural properties of the injection-molded thermoplastic polyamide Vertex ThermoSens denture base resin following a 3-minute immersion in Polident 3-minute denture cleanser. Methods Sixty specimens (Vertex ThermoSens) were processed and divided into two main groups (n = 30) based on the type of test. Group 1 was further subdivided into two subgroups (n = 15): the control group immersed in distilled water (G1DW) and the test group immersed in Polident cleanser solution (G1PD). Group 2 was divided into three subgroups: a non-immersed group (G2None), a group immersed in distilled water (G2DW), and a group immersed in Polident cleanser solution (G2PD). Color change (∆E) and surface roughness measurements were conducted for group 1, and flexural modulus (E) test was performed for group 2. The CIE Lab* formula was utilized to calculate ∆E. An optical 3D surface analyzer and a three-point bending test were employed for surface roughness and E assessments, respectively. Data were subjected to statistical analysis using a paired-sample t-test for differences within each group before and after immersion. Furthermore, independent-sample t-tests and one-way ANOVA were conducted to analyze differences between groups. A significance level of P < 0.05 was considered. Results The results revealed a slight, statistically insignificant (P > 0.05) ∆E in all color components (L*, a*, b*) after immersion in distilled water. However, after immersion in the denture cleanser, only the L* component exhibited a statistically significant ∆E (P = 0.002), which was slight in magnitude. Additionally, a significant difference was found in the ∆E between G1DW and G1PD, with G1PD showing a higher change (P = 0.007). A significant increase in surface roughness after immersion was observed in G1PD (P = 0.017), with a notable difference between G1DW and G1PD. However, the E remained unaffected (P = 0.537). Conclusion Denture cleansers have the potential to modify the properties of thermoplastic polyamide resin. Further research is needed to explore the clinical implications of these observed changes on denture performance.
“It's not just what we say or do, but how we say and do it”

Infant-directed speech (IDS) and infant-directed actions (IDA) represent specific behavioural modifications of adults when they communicate with infants and young children. Infant-directed modifications (IDMs) have specific behavioural representations marked by high positive affection, greater expressiveness, simplification, and increased repetition. Both IDS and IDA appear as part of the same larger behavioural system of IDMs. However, so far, studies have analysed the features and functions of these behaviours separately. Compared to adult-directed speech, IDS is characterised by longer pauses, a slower tempo, more prosodic repetition, higher fundamental frequency, longer vowels, repetitive intonation structures, and greater melodiousness. In IDA, compared to adult-directed actions, the amplitude of movements, simplification, and number of repetitions tend to increase as the distance between communication partners decrease. In this review, we draw a parallel between IDS and IDA to show that adults change both their speech and actions in similar ways and that both actions and speech change depending on the infant’s age and/or developmental stage. We discuss possible (biological) mechanisms that elicit the use of IDS and IDA and argue that this specific type of adult behaviour has a unique impact on how infants perceive and process information. Insights on biological, behavioural, and functional aspects of IDMs could provide a new perspective on the importance of early interactions and knowledge acquisition in both typically developing children and those with developmental disorders.
Online Parameter Estimation for Induction Heating Systems with Quasi-Resonant Inverter

Induction heating has become one of the most dominant heating technology in many industrial and domestic applications. Accurate modeling and control of such heating systems require an estimation of the load and the coil parameters. For the cases without a current sensor, the parameter estimation is usually done at so-called load-detection stage before starting the heating. This process needs, however, a certain execution time, and it is usually implemented by applying computationally-complex algorithms. This paper proposes an online estimation technique to estimate the load and the coil parameters of a quasi-resonant-inverter-topology-based induction heating system. The estimation is performed during the normal operation of the inverter without any pre-operation steps. The proposed method is implemented by fitting the sampled voltage to an exponentially-damped sinusoidal signal. This curve-fitting process is based on an iterative numerical algorithm which does not require any non-linear optimization or complex signal processing steps, thus making the method implementable in the existing digital control platform. An experimental prototype emulating the quasi-resonant-based induction heating system is used to verify the efficiency of the proposed estimation technique.
2017). Amazonian forest-savanna bistability and human impact. Nature Communications, 8,

A bimodal distribution of tropical tree cover at intermediate precipitation levels has been presented as evidence of ﬁre-induced bistability. Here we subdivide satellite vegetation data into those from human-unaffected areas and those from regions close to human-cultivated zones. Bimodality is found to be almost absent in the unaffected regions, whereas it is signiﬁcantly enhanced close to cultivated zones. Assuming higher logging rates closer to cultivated zones and spatial diffusion of ﬁre, our spatiotemporal mathematical model reproduces these patterns. Given a gradient of climatic and edaphic factors, rather than bistability there is a predictable spatial boundary, a Maxwell point, that separates regions where forest and savanna states are naturally selected. While bimodality can hence be explained by anthropogenic edge effects and natural spatial heterogeneity, a narrow range of bimodality remaining in the human-unaffected data indicates that there is still bistability, although on smaller scales than claimed previously.
Coordinated path-following control of multiple underactuated autonomous vehicles in the presence of communication failures

This paper addresses the problem of steering a group of underactuated autonomous vehicles along given spatial paths, while holding a desired inter-vehicle formation pattern. For a general class of vehicles moving in either two or three-dimensional space, we show how Lyapunov-based techniques and graph theory can be brought together to yield a decentralized control structure where the dynamics of the cooperating vehicles and the constraints imposed by the topology of the inter-vehicle communications network are explicitly taken into account. Path-following for each vehicle amounts to reducing an appropriately defined geometric error to a small neighborhood of the origin. Vehicle coordination is achieved by adjusting the speed of each vehicle along its path according to information on the positions of a subset of the other vehicles, as determined by the communications topology adopted. The system obtained by putting together the path-following and vehicle coordination strategies adopted takes a cascade form, where the former subsystem is input-to-state stable (ISS) with the error variables of the latter as inputs. Convergence and stability of the overall system are proved formally. The results are also extended to solve the problem of temporary communication failures. Using the concept of "brief instabilities" we show that for a given maximum failure rate, the coordinated path following system is stable and the errors converge to a small neighborhood of the origin. We illustrate our design procedure for underwater vehicles moving in three-dimensional space. Simulations results are presented and discussed
The Key Factor of Acid Mine Drainage (AMD) in the History of the Contribution of Mining Industry to the Prosperity of the United States and South Africa: A Review

Mining industry has significantly contributed to the prosperity of the nation with economic growth, whereas mining operation has caused Acid Mine Drainage (AMD) with the abandonment of mines. As some researchers suggest, the history of AMD is, generally, affected by the change in not only mining industry but also in social and economic conditions. Thus, historical analysis is an effective way to find the key factors of AMD. In this study, in order to find the key factors of AMD, we examine the history of the United States (U.S.) and South Africa, where their economy had been developed owing to the large-scale mining, based on the findings in the previous studies. The results indicated that the abandoned mines due to the economic depression triggered AMD in the U.S. and South Africa. While the U.S. had progressively adopted anti-AMD methods in terms of prevention, prediction, and remediation (PPR) as a comprehensive approach, especially since the 1970s onwards because of the rise of environmental consciousness as well as strict regulations, South Africa is at the early stage of implementing the regulations following PPR. The public attention should be directed to environmental conservation in addition to the implementation of the regulations in South Africa. The improvement in socio-economic conditions is, additionally, necessary for the rise of environmental consciousness in South Africa in the light of the three pillars of sustainable development: social, economic, and environmental elements.
New sufficient conditions for the solvability of a new class of Sylvester-like absolute value matrix equation

In this article, some new sufficient conditions for the unique solvability of a new class of Sylvester-like absolute value matrix equation \(AXB - \vert CXD \vert =F\) are given. This work is distinct from the published work by Li [Journal of Optimization Theory and Application, 195(2), 2022]. Some new conditions were also obtained, which were not covered by Li. We also provided an example in support of our result.
Prescribed Fire Alters Dissolved Organic Matter and Disinfection By-Product Precursors in Forested Watersheds - Part I. A Controlled Laboratory Study

Detritus material in forested watersheds is the major terrestrial source of dissolved organic matter (DOM) and disinfection by-product (DBP) precursors in source waters. Forest fire reduces the thickness of detritus layer and changes foliar litters into pyrogenic organic matter (PyOM) on the forest floor, resulting in different quantity and quality of DOM exported from forested watersheds. Many studies have examined DBP precursors exported from forested watersheds; however, DOM leaching from PyOM, or dissolved black carbon (BC), could have different reactivity in DBP formation compared to the DOM leaching from unburned detritus layer. Using controlled laboratory burning in this study, characteristics of foliar litters before and after burn were compared. Quality and quantity of water extractable organic matter (WEOM) from raw and burned foliar litters commonly found in the southeastern United States, including baldcypress (Taxodium distichum), boxelder (Acer negundo), longleaf pine (Pinus palustris), pop ash (Fraxinus caroliniana), sweetgum (Liquidambar styraciflua), and water tupelo (Nyssa aquatica) was compared, and evaluated for their disinfection by-product yield and specific DBP formation using a uniform formation condition test. Laboratory analysis