Miracle-dz/UniFAR-FTUs huggingface dataset:
Regression of maturecorneal lymphatic vessels by intracorneal ranibizumab injection

Objective: Ranibizumab is a Fab fragment of a recombinant, humanized, monoclonal anti-vascular endothelial growth factor (VEGF) antibody. This study analyzes the possibility of regressing lymphangiogenesis and hemangiogenesis by intracorneal ranibizumab injection. In addition, the effect of ranibizumab on corneal endothelial cells (CECs) of mice is also studied. Methods: Hemangiogenesis and lymphangiogenesis were induced in female BALB/c mice using the murine model of suture-induced inflammatory neovascularisation. The treatment group received an intracorneal injection of ranibizumab (controls: phosphate buffered saline (PBS)). Corneas were excised at different time points (1 day, 5 days, and 10 days) after the injection, and corneal whole mounts were stained with CD31, LYVE-1, and alizarin red S to quantify hemangiogenesis, lymphangiogenesis, and corneal endothelium. The morphology was analyzed by using the image analysing programme Cell^F and Image J image analysis programme, respectively. Results: In accordance with our previous findings, lymphatic vessels and blood vessels could be reduced after an intracorneal ranibizumab injection: One day after the injection, lymphatic vessels were reduced by 18% (P = 0.4), blood vessels were reduced by 22% (P = 0.083); after 5 days and 10 days, lymphatic vessels were reduced by 50% (P = 0.002) and 63% (P < 0.001), respectively, and blood vessels were reduced by 52% (P = 0.0031) and 68% (P < 0.001), respectively. The corneal endothelial morphology showed no significant differences after the intracorneal ranibizumab injection for 10 days (all P > 0.05). Conclusions: This study is the first to demonstrate that the intracorneal ranibizumab injection is a novel technique to specifically induce regression of corneal lymphatics and blood vessels without affecting corneal endothelial cells.
Evaluation and assessment of Knowledge, Attitude and Practice of Pharmacy students towards Pharmacovigilance in Saudi Arabia: A Cross sectional study.

BACKGROUND: Pharmacovigilance is an important part of the health care system as it helps in the detection, assessment, reporting and prevention of Adverse Drug Reactions. Spontaneous reporting of adverse drug reaction plays a vital role in the success of Pharmacovigilance programs and pharmacy students are supposed to acquire sufficient knowledge and necessary skills required for practicing pharmacovigilance under different clinical settings. Hence, this study was carried out in the students of College of Pharmacy of a University in the Southern Province of Saudi Arabia to assess the Knowledge, Attitude and Practice (KAP) of undergraduate Pharmacy students towards Pharmacovigilance. METHODS: A quantitative, prospective, cross-sectional online survey was carried out using a validated, self-administered questionnaire constituting 4 domains i.e. Demographics, Knowledge, Attitude and Practice of Pharmacovigilance among the pharmacy students of King Khalid University. RESULTS: The questionnaire was administered to 360 students out of which 329 responded (response rate of 91.3 %). The mean score of Level 7,8,9,10 and intern students for Knowledge was (3.03,5.37, 6.38, 6.19,6.42), Attitude (5.28,4.16, 5.62, 5.01, 5.29), and Practice (2.99, 3.25, 3.04, 3.43, 3.13) respectively. In addition, the findings indicated a significant difference in the mean score among different level of students for knowledge and attitude with a p-value of <0.0001, and 0.0002 respectively. The practice mean score showed there was no much significance among different level of students (p-value = 0.4108) CONCLUSION: Our research findings revealed that the pharmacy students of the focused university have adequate knowledge and positive attitude towards adverse drug reaction. However, there is a dire need to understand and address concerns regarding real time practice patterns prevalent among Health Care Providers about pharmacovigilance under different clinical settings. Keywords: Pharmacovigilance, Knowledge, Attitude, Practice, Pharmacy students
Spatial skills of engineering students in the United Arab Emirates

Spatial skills are known to be important to success in engineering, and in particular, to success in engineering graphics/CAD courses. Recent studies demonstrate the link between spatial skills and creativity and innovation. Student spatial skills have been widely studied in the U.S., but work in this area in other parts of the world has been somewhat limited. In a recent data analysis in the U.S, the spatial skills of students by region of origin were examined and it was found that students from Africa, India, and the Middle East tended to have weaker spatial skills when compared to domestic students; however, it is unknown whether this is merely a reflection of the student population who chooses study in the U.S. or if it is generally true for the populations in these regions. In this study, we examined the spatial skills of second year engineering students at the Petroleum Institute in the United Arab Emirates. This paper will outline our findings, comparing the spatial skills of students in the UAE to.
An Empirical Assessment of IT Project Selection and Evaluation Methods in State Government

This study uses a survey of U.S. state government information technology (IT) project management practitioners to investigate the utilization of IT project selection and evaluation methodologies-financial and qualitative–and to assess the empirical relationship between the chosen methods and several measures of perceived project success. The analysis presents evidence that financial project selection and evaluation methodologies appear to be important in obtaining better control over project costs.
UMTS spatio-temporal propagation trial results

The demand for novel signal processing architectures in mobile communication systems has never been greater. This is driven by the increasing demand for multimedia services and the inevitable rollout of 3G cellular systems such as Universal Mobile Telecommunications System (UMTS). Two techniques that are currently being considered to meet this demand are: multi-user detectors (MUDs) and smart antennas. In order to assess the performance of these techniques, the characteristics of the environments is of prime importance. This paper reports on a spatio-temporal measurement system that has been used to measure the multi-dimensional channel characteristics. The trials data can be used to assess the performance of MUDs and smart antennas for UMTS. The system has been used to characterise a number of representative environments, namely: urban, rural, indoor and outdoor-indoor. The channel data allows an appraisal of UMTS Terrestrial Radio Access (UTRA) Frequency Division Duplex (FDD) and Time Division Duplex (TDD) wireless communications systems incorporating novel signal processing techniques. Thus, the relative merits of each can be determined.
ISO 9001:2000 in the Egyptian manufacturing sector: perceptions and perspectives

Purpose – The purpose of this paper is to examine management attitudes/perceptions of Egyptian manufacturing organizations toward the implementation of ISO 9001:2000. The implementation of ISO 9001:2000 depends on how the standard is perceived by Egyptian companies themselves.Design/methodology/approach – The present study is exploratory in nature and seeks to collect data about management attitudes/perceptions towards ISO 9001:2000 through a structured mail survey. Mail questionnaires were sent to 200 manufacturing companies throughout Egypt, yielding a response rate of 35 percent.Findings – Survey results indicated that Egyptian manufacturing organizations are aware of ISO 9001:2000 and it is considered to be relevant to their organizations. The main motivators for seeking ISO certification were to improve the efficiency of the quality system and to achieve customer satisfaction. The vital benefits perceived from implementing the certificate were improved documentation and improvement in the efficiency .
Evacuation experiments in a virtual reality high‐rise building: exit choice and waiting time for evacuation elevators

The egress strategy in high‐rise buildings has traditionally been based on the sole use of stairs for evacuation. However, it is becoming more common to include evacuation elevators in the egress strategy in high‐rise buildings. Traditionally, evacuation elevators have not been allowed as an evacuation route, and people have been instructed to not use elevators in case of fire. This means that people might still not consider evacuation elevators even if they are designed to be safe in case of fire. Even if people choose evacuation elevators, they might not be willing to wait very long for an elevator to arrive. Virtual reality (VR) experiments were conducted to study exit choice and the waiting time for evacuation elevators in high‐rise buildings. The experiment was performed in a VR lab with a VR model of an existing high‐rise building. Results suggest that a simple way‐finding system using green flashing lights can influence people to more likely choose the elevator as their first evacuation choice. The results also show that the general trend is that people wait for either a limited time (<5 min) or a long time (>20 min). Copyright © 2015 John Wiley & Sons, Ltd.
Feminist Epistemology and Business Ethics

Neoclassical economics has become the predominant school of economic thought, influencing scholarship on management, organizations, and business ethics. However, many feminist economists challenge the individualist and positivist foundations of neoclassical economic epistemology, arguing instead that purportedly gender-neutral and value-free methods routinely and systematically leave out and undervalue women. Extending this proposition, this article introduces the epistemic foundations of feminist economics and illustrates how they can produce novel insights relevant for business ethics. In particular, by examining economic phenomena from the point of view of the people they affect, feminist economic epistemology is able to elucidate the ways in which power asymmetries and gender norms that constitute the social world can be reflected in business practices. I apply this methodological insight to three case studies of global supply chains to challenge the neoclassical assertion that including women in labor markets necessarily catalyzes gender equality.
THE ROLE OF LEADERSHIP IN INSTILLING ORGANIZATION CITIZENSHIP BEHAVIOR

This article examines the effect of Transformational Leadership Style on employees’ Organization Citizenship Behavior. The latter is being focused upon as a determinant factor in “individual and group performance”, which, in turn, leads to an effective “organization performance”. The ability to motivate employees to accomplish outside the terms and conditions of their signed work contract is one of many effective leadership’s missions (Bass, 1997). Based on abundant literature, transformational leadership had proven to be effective in managing organizations. Hence, the purpose of this research is to answer the following question: does transformational leadership style affect the development of organizational citizenship behavior? The main objective is to demonstrate how transformational managers implant organization citizenship behavior among their subordinates. The study was conducted in a private hospital in the north of Lebanon on a sample of thirty nurses in both the surgery and the urgent care departments. Choosing the hospital industry, and specifically those two departments, seemed logic in the light of covid-19 pandemic (which caused an increase in the number of admitted patients) and severe economic crisis (which pushed many hospitals to impose salaries’ late payments and cutoffs). I believe that the effect of the managers’ transformational style could be easily depicted in the light of more workload and less rewards. The research findings indicated that transformational leaders considerably impact employees’ organizational citizenship behavior. This fact reveals the necessity of training managers to exhibit their transformational style which will obviously lead to the wellbeing of all stakeholders.
Vehicle longitudinal velocity estimation during the braking process using unknown input Kalman filter

In this paper, vehicle longitudinal velocity during the braking process is estimated by measuring the wheels speed. Here, a new algorithm based on the unknown input Kalman filter is developed to estimate the vehicle longitudinal velocity with a minimum mean square error and without using the value of braking torque in the estimation procedure. The stability and convergence of the filter are analysed and proved. Effectiveness of the method is shown by designing a real experiment and comparing the estimation result with actual longitudinal velocity computing from a three-axis accelerometer output.
Situation Awareness: A Critical But Ill-Defined Phenomenon

Situation awareness has recently gained considerable attention as a performance-related psychological concept. This is especially true in the aviation domain where it is considered an essential prerequisite for the safe operation of the complex dynamic system 'aircraft. ' There are concerns, however, that inappropriately designed automatic systems introduced to advanced flight decks may reduce situation awareness and thereby put aviation safety at risk. Situation awareness has thus become a ubiquitous phrase. It's use is most often based on an intuitive understanding; a commonly accepted definition is still missing. To fill this gap, we analyze the cognitive basis of the concept, embedding it in the context of related psychological concepts. On this basis, methodological approaches to the investigation of situation awareness are discussed.
Hemodynamic Analysis for Olfactory Perceptual Degradation Assessment Using Generalized Type-2 Fuzzy Regression

Olfactory perceptual degradation (OPD) refers to the inability of people to recognize the variation in concentration levels of olfactory stimuli. This article attempts to assess the degree of OPD of subjects from their hemodynamic response to olfactory stimuli. This is done in two phases. In the first (training) phase, a regression model is developed to assess the degree of concentration levels of an olfactory stimulus by a subject from her hemodynamic response to the stimulus. In the second (test) phase, the model is employed to predict the possible concentration level experienced by the subject in [0, 100] scale. The difference between the model-predicted response and the oral response (the center value of the qualitative grades) of the subject about her perceived concentration level is regarded as the quantitative measure of the degree of subject’s olfactory degradation. The novelty of the present research lies in the design of a general type-2 fuzzy regression model, which is capable of handling uncertainty due to the presence of intrasession and intersession variations in the brain responses to olfactory stimuli. The attractive feature of the article lies in adaptive tuning of secondary membership functions to reduce model prediction error in an evolutionary optimization setting. The effect of such adaptation in secondary measures is utilized to adjust the corresponding primary memberships in order to reduce the uncertainty involved in the regression process. The proposed regression model has good prediction accuracy and high time efficiency as evident from average percentage success rate (PSR) and runtime complexity analysis, respectively. The Friedman test undertaken also confirms the superior performance of the proposed technique with other competitive techniques at 95% confidence level.
Induction of Functional Control in Chronic Hepatitis B Patients with Low Level HBsAg Using a Combination of a PreS1/S2/S HBV Vaccine (Sci-BVacTM) and a Nucleoside Analogue

Background: Treatment regimens for chronic hepatitis B virus (HBV) infection are efficient in suppressing viral load and improving hepatocellular injury and its complications. However, current antiviral agents such as nucleos(t)ide analogues or interferon-alpha are inefficient to reconstitute immunologic control of a persistent HBV infection or mediate clearance of HBV DNA. It was hypothesized that high levels of circulating HBV surface antigens (HBsAg) produced by episomal and integrated HBV DNA lead to immune tolerance of HBV and contribute to chronic HBV infection. Hence, low level HBsAg in a fraction of patients may create a window for the reconstitution of a HBVspecific immune response and control of infection. Previous studies in transplant patients indicate that antiviral therapy, in combination with a third generation PreS/S vaccine, may control HBV viremia and induce seroconversion to anti-HBs. Methods: We determined the frequency of low level HBsAg (<500 IU) carriers by a data request in two diagnostic laboratories. Three HBsAg positive, NUC treated, low level HBsAg carriers were immunized with 6 to 11 doses of Sci-B-VacTM. The kinetics of HBsAg reduction, anti-HBs seroconversion and T cell response after vaccination was determined. Results: Approximately 30% of patients with chronic hepatitis B in two large cohorts showed low HBsAg concentrations of <500 IU. Three low level HBsAg carriers with baseline concentrations of 448, 20,2 and 19,2 IU/L HBsAg seroconverted to anti-HBs after being vaccinated with Sci-B-VacTM. Two years after vaccination, the antiHBs titters were 100, 600 and 260 IU/L, respectively. Conclusion: These preliminary data suggest that combining NUC ́s with PreS1/PreS2/S vaccination in low level carriers of HBsAg may provide a new therapy to achieve functional control of chronic hepatitis B by seroconversion to anti-HBs.
An overview of the diffusion of advanced techniques

This chapter addresses a variety of factors influencing the diffusion of advanced techniques in organizations with particular reference to advanced cost and management accounting practices. Having identified almost all of influencing factors addressed in the literature, this chapter also develops a model for the diffusion of advanced techniques and clarifies the most significant group of influencing factors responsible for such a diffusion process from users' point of view.Addressing diffusion of advanced techniques in the global environment as a practical issue requires global evidence, which is almost impossible to provide in a single study. However, to address such an issue and to explore significant factors influencing the diffusion of advanced techniques in the organizations, this chapter relies on the results of recent surveys on the diffusion of advanced cost and management accounting techniques as an example. The diffusion model developed in this chapter is more likely to be applicable to any diffusion study, investigating the diffusion process of either accounting or nonaccounting advanced techniques in the global environment, with minor modification.
The effect of temperature change upon the creep of mortar under torsional loading

Synopsis Details are given of a novel test rig developed to investigate the creep of concrete under varying temperature. Tubes of saturated mortar were subjected to sustained torsional load, and the creep in shear was measured. The results showed that, when the temperature was raisedfor the first time, the creep rate increased greatly in comparison with that of a similar specimen heated before loading. No such change of rate was observed when the temperature was lowered or when it was raised to a level previously attained. It is shown that creep under variable temperature may be considered as the sum of three components: under constant temperature, flow (irrecoverable) and delayed elastic strain (recoverable); and as a result of the first temperature rise, transitional thermal creep (irrecoverable).
Modeling on n-Heptane Pool Fire Behavior in an Altitude Chamber

Airplane as one of the important transport vehicles in our life, its safety problem related to in-flight fire has attracted a wide-spread attention. The combustion behavior of the cabin fire in flight shows some special characteristics because of the high-altitude environment with low-pressure and low oxygen concentration. A low-pressure chamber of size 2 m×3 m×2 m has been built to simulate high-altitude environments, where multiple static pressures for pool fire tests can be configured in the range between standard atmospheric pressure 101.3KPa and 30KPa. Two different sizes of pool fires were tested. Then corresponding modeling were conducted by a LES code FDS V5.5 to examine the mechanism of pressure effect on the n-Heptane pool fire behavior. The burning of liquid fuel was modeled by a Clausius-Clapeyron relation based liquid pyrolysis model. The modeling data was validated against the experimental measurements. The mass burning rate of free-burning pool fire decreases with the decreasing of pressure, which was observed from the modeling to be due to the reduction of flame heat feedback to the fuel surface. Under low pressure, the fire plume temperature increases for the same burning rate. The mechanism of pressure effect on fire behavior was analyzed based on the modeling data.Copyright © 2013 by ASME
An autonomous shunt circuit for vibration damping

This paper describes the implementation of an autonomous switching resistor–inductor (R–L) shunt circuit for the control of structure vibration. The resulting switch shunt circuit, compared to present shunt circuit techniques, does not require a power for its operation and is almost as effective. Moreover, experiments show that the damping performance is robust against temperature variations due to environmental conditions, whereas present shunt circuits lose their damping performance. The proposed autonomous switching R–L shunt circuit requires a small number of electronic components, therefore making it a viable and effective solution for the control of structural vibration.