Miracle-dz/UniFAR-FTUs huggingface dataset:
ANTICANCER EFFECT OF SALVIA (MARAMIA) EXTRACT ON HEP-2 CANCER CELL LINE

Sage (salvia) species have been used for a long time to relief pain; protect the body against viral and bacterial infection and inflammation, treatment of life‑threatening diseases as heart disease, diabetes, and cancer. Many studies advocated sage species for drug development because of their recorded therapeutic effects including anti-proliferative and cytotoxic effects against malignant cells.Objective: Evaluate the anticancer effect of salvia extract.Materials and Methods: A pure extracts from ground leaves of salvia were added to nasopharyngeal carcinoma cell line and to normal cell line as a control. Results: Anti-proliferative effects of Salvia showed the highest cytotoxic effect against nasopharyngeal carcinoma cell line after 28 h of influence. We observed no anti-proliferative effects on the healthy cell line.Conclusions: Our results confirmed the potent genotoxic and anti-proliferative properties of Salvia against laryngeal cancer cell line.
Effects of Moderate Pressure Massage on Self-Regulation & Play in Preterm Babies

Date Presented 04/21/2023 This quasi-experimental study examined whether mother-performed moderate pressure massage could improve self-regulation and play in preterm infants. Results indicated that massage had a calming effect with improvements in self-regulation and play skills. Primary Author and Speaker: Chaya Hendel
RACIAL/ETHNIC DISPARITIES IN PSYCHOTHERAPY: DOES THE OUTCOME MATTER?

This study examined disparities in client psychotherapy outcomes within counselor’ caseloads that occur on the basis of clients’ racial/ethnic minority status. The sample was comprised of the caseloads of 324 therapists who treated a total of 23,168 clients across a number of clinical sites (mostly university counseling centers). Each of the therapists treated at least five White and five Racial or Ethnic Minority clients (REM). Client data were collected at the beginning of each therapy session utilizing the Behavioral Health Measure-20 (BHM-20; Kopta & Lowry, 2002). This measure is comprised of three subscales and each represents a distinct therapy outcome (well-being, symptoms, and life functioning). Disparities were assessed for each outcome domain. Results suggested that therapists did not differ in their abilities to facilitate change in well-being and life functioning across White and REM clients. However, there were significant disparities within therapists’ caseloads between White and REM clients on the symptoms outcome. Some therapists produced reductions in symptoms of equal magnitude with their White and REM clients, while others had greater variability and exhibited greater amounts of symptom change with either White clients or REM clients.
COMPARATIVE EVALUATION OF SMEAR LAYER REMOVAL, CALCIUM IONS LOSS AND DENTIN MICROHARDNESS AFTER DIFFERENT FINAL IRRIGATION SOLUTIONS

Aim: The aim of this study was to evaluate the smear layer removal ability of three different irrigation solutions and their effect on calcium ion loss and dentin microhardness.Materials and Methods: Forty root samples were used in this study. Samples were divided into four groups according to the type of irrigant used as a final rinse into: group A; 5.25% Sodium hypochlorite (NaOCl) (control), group B; 17% Ethylenediamine tetraacetic acid (EDTA), group C; QMix 2in1, and group D; 0.2% Chitosan. After final rinse the measurement of Ca ions loss was done using atomic absorption spectrophotometry. Then, samples were divided longitudinally into two halves. One half of each sample was evaluated for smear layer removal ability using Environmental Scanning Electron Microscope. The other half was examined for dentin microhardness using Vickers microhardness tester. Parametric data were analyzed by One Way ANOVA test then, Games-howell test and Tukey post-hoc test and none parametric data were analyzed by Kruskal-Wallis and Dunn’s test at P ≤ 0.05. Results: NaOCl did not show any smear layer removal ability, while EDTA, QMix, and Chitosan showed complete smear layer removal and patent dentinal tubules particularly at the cervical third. EDTA, QMix, and Chitosan recorded the highest Ca ion loss and the lowest microhardness than NaOCl. Conclusion: EDTA, QMix, and Chitosan significantly removed smear layer and so released higher amount of Ca ion which adversely affect the microhardness. It remained difficult to completely remove smear layer from the apical third and so it recorded the highest microhardness.
PRODAMAS and the Effect on Infrastructure Growth

The Community Empowerment Program has been the center of topic discussed in Indonesia in the past few periods. This is also related to government policies that are intensively focus on infrastructure development and regional community empowerment. In accordance with the facts, the condition of the Indonesian who scattered in various regions does require serious attention. The community empowerment program is indeed felt to be able to encourage the spirit of the community to be more advanced and developing to adjust the global conditions nowadays. In order for the development of society to face globalization towards a better direction, a community empowerment program as well as continuous assistance is needed. This study aims to analyze the possible impact of economic growth caused by infrastructure development. This study focuses on a community empowerment program called PRODAMAS, from Kediri, East Java. We use observation to analyses the impact of PRODAMAS to infrastructure growth. However, the most important thing about the existence of community empowerment programs is especially the basic culture of the community is slowly being eroded by globalization, namely mutual cooperation and the spirit of development. PRODAMAS as one of community program still needs to be developed continuously rather the ongoing empowerment process can ultimately achieve the goals of an empowered society. Allocation fund of PRODAMAS need to evaluate.
Virulence determination of three Iranian isolates of Salmonella Enteritidis in day-old layer chicks.

BACKGROUND: Salmonella Enteritidis (SE) infection in poultry is one of the most important concerns in poultry. Virulence and pathogenicity of the SE isolates from Iran have not been well studied so far. OBJECTIVES: In the present study, three Salmonella Enteritidis (SE) isolates were compared with a standard SE strain (PT21) for virulence in one-day-old layer chicks. All of the isolates were supposed to be virulent because of carrying a large-sized virulence plasmid. METHODS: Fifty day-old layer chicks (LSL strain) were divided into five groups of 10 chicks and raised in separate cages until 14 days of age. All three SE isolates were cultured in brain-heart infusion (BHI) broth to reach a concentration of approximately 1010 CFU/ml. The challenged groups included three groups inoculated with three SE isolates (A20, S32, S34) and one group inoculated with SE PT21 as positive control. One group was raised as negative control without receiving any bacteria. Any mortality or morbidity observed in any group was recorded. Samples were taken from liver, jejunum and cecum at days 2, 4, 6, 9 and 14 days of age, cultured for SE isolation, colony counting and histopathological examinations. RESULTS: All challenged groups showed mild to severe diarrhea in all birds and some birds were listless especially in the first week. No signs were seen in the control group. Two mortalities occurred in challenged groups. Salmonella Enteritidis was detected in all samples until the end of experiment. The colony count showed less (100 to 1000 times less) SE in liver compared to that of cecal samples. Histopathological findings also were compatible with symptoms and bacteriological results. CONCLUSIONS: We concluded that all three SE isolates were able to colonize in the digestive system of layer chicks leading to mortality or at least lower performance compared to healthy chicks
Changes of Salivary Interleukine-17, Apelin, Omentin and Vaspin Levels in Normal Subjects and Diabetic Patients with Chronic periodontitis

Background: Chronic periodontitis is a chronic inflammatory disease which is multifactorial. Diabetes mellitus is one of the major systemic factors to influence the severity of chronic periodontitis. Therefore, the aim of current study was to assess salivary biomarkers of Interleukine-17(IL-17), apelin, omentin and vaspin as putative candidates in the potential association between Diabetes mellitus and Chronic periodontitis. Methods: Whole saliva samples were collected from sixty adults sex and agematched patients who were further divided into two groups; healthy (control group; n = 30) and diabetic individuals with chronic periodontitis (n = 30). Salivary IL-17, apelin, omentin andvaspin concentrations were determined by standard enzyme-linked immune-sorbent assay. Results: Salivary levels of IL-17, apelin and vaspin were significantly higher in diabetic patients with periodontitis group compared to control group. On the other hand, salivary levels of omentin were significantly lower in diabetic patients with periodontitis compared to control group. Conclusions: Our study supports the hypothesis that abnormal production of IL-17, apelin, omentin and vaspin can contribute to the pathogenesis of diabetes-related complications including Chronic periodontitis.
Physical Activity and Healthy Eating Promotion among Adults with Cardiovascular Metabolic Risk Factors: An Application of Intervention Mapping Framework

Background: Intervention mapping (IM) is a systematic development of interventions for designing health promotion programs. Objectives: Promotingphysicalactivity(PA)aswellashealthyeating(HE)hasanimportantroleinimprovingindividualswithcar-diovascularmetabolicriskfactors(CVMRFs). Thispaperdescribesdevelopmentof aninterventionbasedoninterventionmappings’ steps to promote PA and HE among Iranian adults with CVMRFs. Methods: Wedevelopedaninterventionfollowing6stepsofIMframeworkandPRECEDEModel. Needsassessment(Step1)consisted of interviewswith 50adultswithCVMRFand12 healthcareproviders(HPs)locatedinKaraj, Irantoknowif their perceptions of risk behaviors are related to the CV risk factors as well as predisposing, enabling and reinforcing factors for PA, and HE behaviors. Next, we conducted a survey with 450 patients to assess the relationship between determinants and 2 behaviors. Then a program was plannedforchangeabledeterminantsbasedon2-4stepsof IM,andﬁnallyaplanforimplementation(Step5)andevaluation(Step 6) was developed. Results: Findingsof thequalitativepartshowedunhealthyeatingandinactivityasbehaviorsthatpredictCVMRFsandalsothethe-oreticaldeterminantsthatwererelatedtoengagementinPAandHEincluded;self-eﬃcacyandperceivedbarriers(predisposingfac- tors), individual skills, laws and policies (enabling factors), and social support, motivation to comply and behavioral consequences (reinforcing factors). The steps 2 to 6 of IM was conducted based on the ﬁndings of the needed assessment. Conclusions: IM, as systematic development of a theory-based intervention, is a suitable frameworkto design comprehensive programs in order to promote healthy behaviors and reduce CV metabolic risk factors.
INDOOR AIR QUALITY AND OCCUPANT HEALTH IN THE RESIDENTIAL BUILT ENVIRONMENT: FUTURE DIRECTIONS

In North America, there are ~140 million homes and 4 million public buildings. More than one fifth of the energy use in Canada is used to condition air whether from the cold in much of Canada or provide cooling and heating where summers are hot and humid and winters are cold. To reduce greenhouse gases and improve housing affordability, this energy use needs to be reduced. In 1981, the Federal and Provincial governments understood that science was needed to inform building codes in relation to occupant health. Ventilation standards used in North America were developed during the late 19 century from studies done mainly in schools. Modern studies of ventilation rate and health effects in public buildings indicate that relative risk for increased respiratory disease and absenteeism becomes significant around 14 L/s per person. Most of this work has been done in public buildings. In Canada, there has been interest in ventilation questions for residential housing in relation to comfort, disease transmission and relationships of ventilation to dampness and pollutants mainly derived from vehicle traffic as well as endotoxin. Considering new homes with heat recovery ventilators, occupants reported improvement over 1 year in the symptoms of throat irritation, cough, fatigue, and irritability in comparison with control new home occupants. Homes that have low per person ventilation rates, and, those that are air leaky are prone to dampness with the associated increased risks of asthma and upper respiratory disease. In the most under-ventilated homes in Canada (in the far north), increased infectious disease has been observed in infants. Lastly, both gaseous and particulate air contaminants infiltrate homes. This is affected by ventilation and other aspects of system design and appears to modulate allergic responses. New studies are needed on the effect of ventilation on health to prevent negative effects on population health consequent to changes in energy codes for residential homes.
Effects of estrogen deprivation on memory and expression of related proteins in ovariectomized mice

Background The ovariectomized (OVX) rodent model is most widely used for studying the influence of estrogen deprivation on memory. However, the results of these studies are inconsistent, in that the memory of OVX rodents shows either impairment or no change. These inconsistent outcomes increase the difficulty of researching neurochemical mechanisms and evaluating drug efficacy. One possible explanation for these discrepancies might be that the time point for memory examination after OVX varies considerably among studies. The aim of our study was to investigate the effects of estrogen deprivation on memory and the expression of memory-related proteins at different times after OVX. Methods Novel object recognition (NOR), step-through passive avoidance (STPA) and the Morris water maze (MWM) were performed to evaluate the memory performance of mice at different times after OVX. The expressions of BDNF, TrkB, ULK1 and LC3II/LC3I in the hippocampus were also assessed to explore the relevant mechanisms. Results After OVX, a significant memory impairment was found in the STPA test at 4 weeks. In the NOR and MWM tests, however, memory deficits were not observed until 8 weeks post-OVX. Interestingly, at 8 weeks, a memory rebound was found in the STPA test. In the hippocampus, the levels of BDNF and TrkB in OVX mice were markedly decreased at 4 and 8 weeks. Subsequently, a significant decrease in the ULK1 and LC3II/LC3I level in OVX mice was observed at 8 weeks. Conclusions Memory impairment in mice was observed as early as 4 weeks after OVX, although there was a possibility of memory rebound with the prolongation of estrogen deprivation. Eight weeks of estrogen deprivation would be more likely to induce hippocampus-dependent memory impairment. This progressive impairment of memory might be due to the downregulation of the BDNF/TrkB signaling pathway at the early post-OVX stage, while the decrease of autophagy level in the later stage might also contribute to these progressive alterations. The underlying relationship between the BDNF/TrkB signaling pathway and autophagy in this progressive impairment of memory requires further study.
The prevalence and severity of periodontitis in a Polish cross-sectional gerodontological study

Introduction: Evaluation of the prevalence and severity of periodontitis as a significant aspect in the overall assessment of oral health and needs of integrated treatment in gerodontology was performed. Objectives: In the population aged 65-74 evaluation of prevalence and severity of periodontitis as definied by CDC/AAP in the Polish cross-sectional epidemiological study. Material and methods: A total of 1,200 people aged 65-74, living in a city (Wrocław, 630,000 population) and in a small town (Oława, 33,000 population) located in southwestern Poland were randomly selected to participate in the study. 285 people from Wrocław and 102 from Oława took part in the epidemiological study. In a clinical dental examination the following aspects were assessed: the number of teeth, bleeding on probing (BoP), pocket probing depth (PPD) and the clinical attachment level (CAL) for all teeth at 4 measurement points. A periodontal diagnosis was made according to the CDC/AAP criteria. In the anamnestic study, variables related to the socio-economic status, systemic conditions and behavioral factors related to selected oral health behaviors were determined. Results: The prevalence of periodontitis was 47.9% (20.8% moderately advanced and 21.2% severely advanced). Statistically, periodontitis occurred more frequently in persons with current nicotine addiction, with a history of a cardiovascular incident and also in men. In the multifactorial model it was found that the significant protection against periodontitis is related to the highest personal income, the correct pattern of daily tooth brushing and self-financed dental treatment, whereas the history of a cardiovascular incident is associated with its occurrence. Conclusions: The prevalence of periodontitis in seniors of Lower Silesia is lower, while the presence of its severe form is comparable to the findings of foreign regional studies.
The Effects of Tricalcium Phosphate and Novamin Remineralizing Agents on Microhardness of Bleached Enamel with 35% Hydrogen Peroxide-An In vitro Study

Objectives: The aim of the present study was to evaluated the effects of remineralizing agents (Tricalcium phosphate and Novamin) on microhardness of bleached enamel surface with 35% hydrogen peroxide (in office). Materials and Methods: Forty human permanent maxillary premolars free from caries or enamel malformation were used. The teeth were sectioned transversally across the cemento-enamel junction, and specimens were embedded in self-cure acrylic. The labial enamel surface faced upward and then they were ground flat and polished with silicon carbide abrasive papers. A total specimen were prepared and kept in deionized water. Then the specimens were drying subjecting them for baseline microhardness testing (control). The dental bleaching treatment was performed just on the labial enamel surface of the specimens using a commercial 35% hydrogen peroxide Whitness HP bleaching gel (in-office ). It was used according to the manufacture instruction. Microhardness was tested for all specimens after bleaching. Specimens were divided into two groups according to remineralizing agent n=20, Group I: Treated by NUPRO Sensodyne with NovaMin, Group II: Treated by Clinpro™ White Varnish Tri-Calcium Phosphate. The remineralizing agent was applied for three minutes per day. Two remineralizing agents were applied for fourteen consecutive days. After each application procedure, the specimens were washed with deionized water and then kept in artificial saliva. At the end of the fourteen days the remineralized specimens were subjected to microhardness testing and values were recorded. All the data were analyzed by ANOVA and Tukey’s post hoc test. Results: Results revealed that a statistically significant decrease on mean microhardness values after enamel bleaching compared to control, followed by a significant increase on mean microhardness after the application of the both remineralizing agents. One way-ANOVA showed a statistically insignificant difference between NUPRO Sensodyne with NovaMin and Clinpro™ White Varnish at p≥0.05. Conclusions: Based on the results of this in vitro study both Tricalcium phosphate and Novamin are effective in remineralization of bleached enamel surface and no significant difference was detected in their efficacy.
EXPENDITURE ON CATERING SERVICES ACROSS EUROPEAN HOUSEHOLDS’ BUDGETS

The aim of the paper is to recognize and estimate alterations in expenditures on catering services across European households, with particular emphasis on households in Poland. The research material was obtained from the Statistics of Poland (GUS) and Eurostat. The research covers 2012 and 2016. It showed the increase of the share of expenditure on catering in total expenditure. It also showed statistically significant differences in the share for expenditure on catering in total expenditure between EU countries and types of Polish households by their demographic and social characteristics.
Interactive English Language Learning: DishZle Language Game

English language learning is often perceived as a static mode of classroom learning activities. Hence, interactive teaching materials are necessary for grabbing learners’ attention span and interests, and in enhancing their involvement. DishZle - a 2-in-1 self-designed language game, focuses on vocabulary and sequencing activities. DishZle deals with various local traditional Malaysian dishes. Hence, the game introduces the learners to the special and unique ingredients and the processes involved in preparing the dishes. They can develop their knowledge of local dishes and improve their proficiency in the English language (speaking, vocabulary and linkers). The game is suitable for beginner to intermediate learners of English (as lead-in activity or post activity of a lesson) in which it introduces cultural topics, which are related to local dishes to their students. This study is a preliminary study to identify the participants’ reactions towards DishZle (effectiveness of using this game in learning the vocabulary and sequencing skills), language learning challenges they face during the game and suggestions to improve the game. The method used was a semi-structured interview, involving 17 participants (diploma students). Most participants claimed that both games were interesting, fun, interactive (communicate with team members) and informative (learn new words and steps to prepare local dishes). It is recommended that language games can often be used as part of teaching methods in ESL classroom as they enhance fun learning, communicative competency, teamwork and
ENERGY CONSUMPTION AND ECONOMIC GROWTH IN NIGERIA: A TEST OF ALTERNATIVE SPECIFICATIONS

The debate on the nexus between energy consumption and economic growth continues unabated with divergent views on the direction of the relationship. This is partly due to the sources and patterns of energy consumption across different countries, differential characteristics of the economies, and differences in the methodologies employed. Again, the mixed and inconclusive results from prior cointegration tests might have arisen from the assumption of symmetry when, in actuality, the response of economic growth to energy consumption may be asymmetric. Furthermore, for studies that employed the asymmetric cointegration analysis, the data generating process might account for the conflicting evidence, especially for annual series. Therefore, this paper re-evaluates the relationship between energy consumption and economic growth in Nigeria over the period 1999Q1–2016Q4 using alternative model specifications. Specifically, the study used a nonlinear (or asymmetric) ARDL model and an ARDL-ECM specification which presumes a linear relationship rather than a nonlinear one. Overall, we find that the role of energy consumption as a driver of growth remained negligible throughout, suggesting that a lot still needs to be done to ensure that the expected role of energy begins to manifest in the Nigerian economy. The Granger causality tests revealed a unidirectional causality running from energy consumption to economic growth, indicating that Nigeria can attain high levels of sustainable growth with improved and stable energy supply. Thus, the study concludes that these findings constitute a wake-up call on governments and policymakers in Nigeria and other Sub-Saharan African economies that share structural similarities with it that there is an urgent need to evolve and implement policies that will address the energy challenges of these economies.