Miracle-dz/UniFAR-FTUs huggingface dataset:
Design of Novel Molecular Micelles for Capillary Electrophoresis

The research presented in this dissertation involves the synthesis, characterization, and application of novel anionic and cationic chiral molecular micelles in capillary electrophoresis (CE) for the separation of diverse chiral compounds. Chapter 1 presents brief overview of the surfactants, micelle polymer, CE and micellar electrokinetic chromatography (MEKC). Chapter 2 describes the simultaneous enantioseparation of eight single chiral center β-blockers using two novel leucine and isoleucine based polymeric surfactants. The simultaneous enantioseparation of multichiral center bearing β-blockers, nadolol and labetalol is described in chapter 3. A synergistic approach, using a combination of polysodium N-undecenoxycarbonyl-L-isoleucinate (poly-L-SUCIL) and sulfated β-CD showed dramatic enantioseparation of four stereoisomers of nadolol. On the other hand for labetalol, enantiomeric separation remains unaffected using the dual chiral selector system. Chapter 4 deals with the enantiomeric separation of the binaphthyl derivatives that was found to be influenced by pH, type and concentration of the background electrolyte as well as concentration of the polymeric surfactant. In chapter 5, characterization of five alkenoxy leucine-based surfactants with variations in chain length (C8-C11), polymerization concentration and degree of polymerization showed significant effects on the chiral resolution and efficiency of hydrophobic βblockers. The synthesis and characterization of two positively charged amino acid derived chiral ionic liquids (ILs) and their corresponding polymers is presented in chapter 6. Chiral separation of two acidic analyte (difficult to resolve with anionic micelles) can be achieved with both monomers and polymers of ILs. In chapter 7, the synthesis and detailed characterization of three pH independent amino acids derived (L-leucinol, L-isoleucinol and L-valinol) sulfated chiral polymeric surfactants is presented. These chiral sulfated surfactants are thoroughly characterized and the morphological behavior of polymeric sulfated surfactants is revealed using cryogenic high-resolution electron microscopy. The work clearly demonstrates for the first time the superiority of chiral separation in MEKC coupled to mass spectrometry at low pH. Finally, in chapter 8, six amino acid derived chiral surfactants with carboxylate and sulfate head groups were compared for enantioseparation of broad range of structurally diverse racemic compounds at neutral and basic pH conditions. INDEX WORDS: Molecular Micelles, Chiral Separations, β-blockers, Multichiral Center β-blockers, Binaphthyl Derivatives, Phenylethylamines, Benzoin Derivatives, PTHAmino Acids, Benzodiazepinones, Cryogenic High-Resolution Electron Microscopy, Polar head Group, Hydrophobic Chain Length. Design of Novel Molecular Micelles for Capillary Electrophoresis A Dissertation Submitted in Partial Fulfillment of the Requirements for the Degree of Doctor of Philosophy in the College of Arts and Sciences Georgia State University
Revisiting the Clockwork Orange: A Review of Theories of Aggressive Behaviour from the Perspective of the Ecological Systems Theory

This paper aims to provide an analysis of principal theories and empirically proven risk and protective factors in the aetiology of violence and aggressive behaviour from the perspective of the Ecological systems theory. The paper is set to review theoretical and empirical findings on key factors in the development of aggressive behaviour. It starts with the individual level (genes, individual traits), across the microsystem and mesosystem (family, school, peers), through the exosystem (community, media, parent’s workplace) only to include the broadest aspect of the macrosystem (culture, norms, governance, war, natural disasters). We present an overview of the most recent research findings on aggressiveness and violent behaviour as an impetus for public-health strategies and educational interventions that could prevent the development of aggression and violence in at-risk populations. on answering questions about the latest research evidence on empirically proven risk and protective factors in the aetiology of aggressive and violent behaviour, with particular emphasis on the importance of their proximal or distal impact. The paper aims to provide an overview of empirically established risk and protective factors in the aetiology of aggressive behaviour from the perspective of the Ecological systems theory. The main focus of the paper is placed on analysing the significance and shortcomings of major biological, psychological and social factors in the development of aggressive behaviour, in an effort to enhance public-health strategies and interventions that could prevent the development of aggression and violence in vulnerable populations.
A Recommender System for Mobile Applications of Google Play Store

With the growth in the smartphone market, many applications can be downloaded by users. Users struggle with the availability of a massive number of mobile applications in the market while finding a suitable application to meet their needs. Indeed, there is a critical demand for personalized application recommendations. To address this problem, we propose a model that seamlessly combines content-based filtering with application profiles. We analyzed the applications available on the Google Play app store to extract the essential features for choosing an app and then used these features to build app profiles. Based on the number of installations, the number of reviews, app size, and category, we developed a content-based recommender system that can suggest some apps for users based on what they have searched for in the application’s profile. We tested our model using a k-nearest neighbor algorithm and demonstrated that our system achieved good and reasonable results.
Tobacco Growth Promotion by the Entomopathogenic Fungus, Isaria javanica pf185

Abstract Isaria javanica pf185 is an important entomopathogenic fungus with potential for use as an agricultural biocontrol agent. However, the effect of I. javanica pf185 on plant growth is unknown. Enhanced tobacco growth was observed when tobacco roots were exposed to spores, cultures, and fungal cell-free culture supernatants of this fungus. Tobacco seedlings were also exposed to the volatiles of I. javanica pf185 in vitro using I-plates in which the plant and fungus were growing in separate compartments connected only by air space. The length and weight of seedlings, content of leaf chlorophyll, and number of root branches were significantly increased by the fungal volatiles. Heptane, 3-hexanone, 2,4-dimethylhexane, and 2-nonanone were detected, by solid-phase micro-extraction and gas chromatography-mass spectrophotometry, as the key volatile compounds produced by I. javanica pf185. These findings illustrate that I. javanica pf185 can be used to promote plant growth, and also as a biocontrol agent of insect and plant diseases. Further studies are necessary to elucidate the mechanisms by which I. javanica pf185 promotes plant growth.
Limited genetic evidence for host plant‐related differentiation in the Western cherry fruit fly, Rhagoletis indifferens

The shift of the fruit fly Rhagoletis pomonella (Walsh) in the mid‐1800s from downy hawthorn, Crataegus mollis (Torrey & Asa Gray) Scheele, to introduced domesticated apple, Malus domestica (Borkhausen), in the eastern USA is a model for ecological divergence with gene flow. A similar system may exist in the northwestern USA and British Columbia, Canada, where Rhagoletis indifferens Curran (Diptera: Tephritidae) attacks the native bitter cherry Prunus emarginata (Douglas ex Hooker) Eaton (Rosaceae). Populations of R. indifferens have shifted and became economic pests on domesticated sweet cherry, Prunus avium (L.) L. , shortly after sweet cherries were introduced to the region in the mid‐1800s. The fruiting phenologies of the two cherries differ in a similar manner as apples and hawthorns, with domesticated sweet cherries typically ripening in June and July, and bitter cherries in July and August. Here we report, however, little evidence for genetic differentiation between bitter vs. sweet cherry populations of R. indifferens or for pronounced genetic associations between allele frequencies and adult eclosion time, as has been documented for apple and downy hawthorn flies. The current findings support a previous more geographically limited survey of R. indifferens in the province of British Columbia, Canada, and an analysis of its sister species, R. cingulata, in the state of Michigan, USA, implying a lack of host‐related differentiation for flies infesting different cherry host plants. Possible causes for why host races are readily genetically detected for R. pomonella but not for R. indifferens are discussed.
Optimization of N fertilization for hops (Humulus lupulus) in Iowa soils

Due to the increased production of local craft beers in the state of Iowa, interest in local hops has been piqued. In order to support the budding hop industry in the Midwest United States, regionally relevant empirical research is necessary, specifically regarding nitrogen (N) fertilizer recommendations. In order to refine fertilizer recommendations for the Midwest, a hop yard was established, and two experiments were conducted. The objective of the first experiment was to determine the optimal concentration of urea (U) to maximize yield and quality, defined as the percentage of αand β-acids in the final dried cones. It was hypothesized that a specific amount of urea would be optimal to support biomass accumulation and maintain quality. To test this hypothesis seven concentrations of U were tested, starting at 0 lb N∙a to 300 lb N∙a in 50 lb N∙a increments. Quality and yield were measured at the end of each growing season. As the concentration of urea increased yield also increased, but quality, specifically the percentage of α-acids declined. Based on experimental results, 150 lb N∙a may be recommended in order to maintain quality and support biomass accumulation. The objective of the second experiment was to determine the optimal form of N fertilizer. It was hypothesized that a nitrate (NO3 ) based fertilizer would promote biomass accumulation. To test the hypothesis, an experiment was conducted with five combinations of N fertilizer applied in split-application at a concentration of 150 lb N∙a. The combinations were made up of calcium nitrate (CN), urea ammonium nitrate (UAN), and U applied in the following combinations (first application-second application): CN-CN, CN-UAN, U-U, U-UAN, and UAN-UAN at 75 lb N∙a per application. Nitrate-based fertilizers resulted in higher yields and may be recommended to support biomass production. Quality was unaffected by N form.
Using a Bayesian Framework to Develop 3D Gestural Input Systems Based on Expertise and Exposure in Anesthesia

i ACKNOWLEDGMENTS . iv LIST OF TABLES . viii LIST OF FIGURES . ix CHAPTER ONE: OVERVIEW . 1 Research Objective and Questions . 3 CHAPTER TWO: LITERATURE REVIEW AND RESEARCH FRAMEWORK . 4 Gestural Technology . 4 Applications of Gestural Technology . 7 Operating Room . 11 Anesthesia Workstation . 13 Barriers to Adoption of Gestural Technology . 15 Technical Barriers . 15 Human Factors Barriers . 16 Skills-, Rules-, and Knowledge-Based Behavior . 19 Bayesian Framework . 22 Research Objective and Questions . 25 CHAPTER 3: INVESTIGATING THE EFFECT OF DOMAIN EXPERTISE ON GESTURAL BEHAVIOR WITHIN THE CONTEXT OF ANESTHESIOLOGY . 27 Introduction . 27 Methods. 28 Participants . 29 Study Design . 29 Equipment . 36 Procedure . 37 Intuitive Gestures Measure . 38 Reaction Time Measure . 39 Results . 42 Intuitive Gesture Mappings . 44 Reaction Times . 46 Discussion . 51 CHAPTER 4: A STUDY INVESTIGATING THE EFFECT OF EXPOSURE AND WORKLOAD ON GESTURE BEHAVIOR IN A GENERAL HCI CONTEXT . 55
THE RELATIONSHIP BETWEEN LEVERAGE AND THE VALUE OF REAL ESTATE COMPANIES LISTED ON THE INDONESIA STOCK EXCHANGE WITH MEDIATORS IN THE FORM OF INVESTMENTS AND DIVIDENDS

To determine the relationship between leverage and the value of real estate companies listed on the Indonesia Stock Exchange with mediators in the form of investments and dividends. The population used in this study was 44 real estate companies listed on the Indonesia Stock Exchange. There is one exogenous variable, namely leverege (X) and two endogenous variables, namely dividend (Y1), and firm value (Y2). The tool used as an analysis method is Generalized Structural Component Analysis (GSCA). The study finds indications that the use of leverage by companies affects the dividend policy, for cases in Indonesia. Creditors have an interest in channeling funds to the company, dividend payments will cause the transfer of welfare from creditors to shareholders of the company, is weak, because there is already an alignment of interests between the creditors and the company. The negative impact of using high leverage on the creation of the company value. High dividend payments will cause a decrease in the value of the company. The market will react negatively when a company pays dividends. The reason is that when a company pays dividends, the company is indicated not to have a profitable growth opportunity or investment in the future. Previous studies conducted tests on the interaction between leverege, investment, dividends, and company value with the results that indicate that inconsistencies are recorded in the results of research that cause gaps. The focus of this research is the real estate industry which is listed on the Indonesia Stock Exchange.
Epidemiological characteristics and some risk factors of extrapulmonary tuberculosis in Larache, Morocco

Introduction this work aims to bring out the epidemiological characteristics of extrapulmonary tuberculosis (EPTB) in the province of Larache (Morocco) and to investigate the effect of gender and age on its localization and treatment outcome. Methods it consists in a retrospective study based on 2962 cases of EPTB, reported during the period 2000 to 2012. Results the mean age was 31.74 ± 18.83 years, with a median age of 26. Males are more affected by this form of tuberculosis, with a male to female sex-ratio of 1,15. The EPTB affects particularly the young population whose age is between 15 and 34 years. The pleural and lymph node localizations are the most common with 45% and 28% respectively. The statistical analysis reveals that younger patients are preferentially affected by lymph node tuberculosis whereas oldest ones are more likely to suffer from urogenital and pericardial tuberculosis. Regarding the treatment outcome, we demonstrated that age is significantly associated with the treatment outcome and that deaths occur preferentially in the oldest patients. Finally, we found out a significant association between males and pleural ETB localization, and between females and lymph node and peritoneo-itestinal ETB localizations. Conclusion special attention must be paid to the mentioned most vulnerable categories of EPTB patients.
Lexical networks between sounds and meanings in Taiwan Mandarin: Evidence from psycholinguistics

The present study aims to provide an outline of lexical networks between sounds and meanings in Taiwan Mandarin. Both the phonological and semantic relations are explored by a free word association task. Previous research has demonstrated a significant influence of phonology on Indo-European networks and suggested the influence of semantics on languages with lexicography such as Mandarin. With a new methodology in which word frequency, syllable type, syllable structure, tone structure, imageability, and parts of speech are carefully considered for the experimental stimuli, a total of 248 responses were collected from six Taiwan Mandarin native speakers. The results of lexical associations suggest that: 1) semantic relations show a stronger connection than phonological ones in Taiwan Mandarin networks; 2) rhymes present a stronger influence on associations than initial segments. The understanding of lexical organization in the human brain may contribute to further research on functions of associations and networks between human and artificial intelligence.
Effect of arginine and threonine in ovo supplementation on immune responses and some serum biochemical attributes in broiler chickens

Abstract This experiment was conducted to investigate effects of in ovo injecting arginine (Arg), threonine (Thr) and Arg + Thr on humoral immunity, serum differential leukocyte counts and serum biochemical attributes in broiler chickens. Four hundred fertile eggs were randomly assigned to five experimental treatments including: control (none injected), sham (0.5 ml of 0.5% saline), Arg (35 mg/egg), Thr (25 mg/egg) and Arg + Thr (35 + 25 mg/egg) which injected in the amniotic fluid on day 14 of incubation. After hatching, broiler chicks were fed a commercial corn–soya bean diet up to 42 days of age. Broilers received Arg and Thr had higher body weight (p < .05) and daily feed intake (p < .05) than those supplemented with control or sham. Antibody titre against sheep red blood cells increased in broilers in ovo supplemented with amino acids compared to the birds in control group (p < .05) while no beneficial effect of applied treatments observed on the antibody titre against influenza and Newcastle disease viruses. Moreover, in ovo injection of Arg significantly increased spleen and bursa of Fabricius relative weights compared to sham on day 11 of age (p < .05). In ovo administration of Thr resulted in higher serum glucose concentration than the other groups (p < .05). Furthermore, serum albumin concentration increased in response to Thr administration compared to chickens in control group (p < .05). In conclusion, Arg and Thr in ovo supplementation improved humoral immunity of broilers and increased proportional weight of their lymphoid organs in post-hatch period. Highlights In ovo injection of amino acids may improve immune responses in broiler chickens. Supplementation of amino acids during embryonic stage could increase growth performance of chickens. Meet the nutrient requirement of broiler embryo is important for its later growth and immunity.
Interactions of nuclear transport factors and surface-conjugated FG nucleoporins: Insights and limitations

Protein-protein interactions are central to biological processes and the methods to thoroughly characterize them are of great interest. In vitro methods to examine protein-protein interactions are generally categorized into two classes: in-solution and surface-based methods. Here, using the multivalent interactions involved in nucleocytoplasmic transport as a model system, we examined the utility of three surface-based methods in characterizing rapid interactions involving intrinsically disordered proteins: atomic force microscopy, quartz crystal microbalance with dissipation, and surface plasmon resonance. Although results were comparable to those of previous reports, the existence of previously overlooked mass transport limitations was revealed. Additional experiments with a loss-of-interaction mutant variant demonstrated the existence of additional physical events and an uncharacterized binding mode. These results suggest the binding events that take place on the surface are more complex than initially assumed, prompting a need for re-interpretation of previous data.
Sonographic Assessment of Some Abdominal Organs in Children with Sickle Cell Disease in Ilorin, Nigeria

Background: The irregular sickle cells can block blood vessels, causing tissue and organ damage and in most cases presented with pain as a result of organ ischemia. Ultrasonography is an easily available instrument for investigating abdominal organs which are most commonly affected by sickle cell disease (SCD). This study was aimed to assessing liver, gall bladder, spleen, and kidney in children with SCD in Ilorin, Kwara State. Methods: A prospective cross-sectional study was conducted among children with SCD in Ilorin from September 2017 to April 2018. An ethical approval was obtained from the Human Research and Ethics Committee of the Kwara State Ministry of Health. In this study, 106 children with SCD and 106 normal children for control were included. Abdominal ultrasound scan was performed on all the selected subjects and the findings were recorded on the data capture sheet. Descriptive and inferential statistic was used in the data analysis, SPSS version 20 was used and the P = 0.05. Results: In the children with SCD, hepatomegaly was found in 45 (42.5%), 29 (27.4%) had coarse echo pattern of liver and 16 (15.1%) had hyperechoic liver, 5 (4.7%) had gallbladder stone, 2 (1.9%) had gallbladder sludge, and 6 (5.6%) had thickened gallbladder wall. Twenty-five (23.6%) had splenomegaly, and 7 (6.6%) had autosplenectomy. Four (3.8%) showed reduced corticomedullary differentiation in each kidney, five (4.7%) in each kidney had mild calyceal dilatation. One (0.9%) had mild calyceal dilatation with reduced corticomedullary differentiation with accompanying loss of renal sinus fat. Conclusion: Abdominal ultrasound imaging for patients with SCD showed a high incidence of abdominal abnormalities, especially in solid organs such as liver, kidney, and spleen.
Notes on the breeding of large Lake Tana Barbs ( Labeobarbus Spp.) in nature and laboratory

The largest lake species flock within cyprinids comprises of 16`Lake Tana (Ethiopia) Labeobarbus species differing in ecology, morphology, and sites of reproduction. Most of them migrate to rivers for spawning and head down to the lake after spawning. During 2005−2015, species composition of Lake Tana barbs was studied in five rivers and their tributaries including those so far not sampled. Our observations revealed that several species, earlier considered to spawn in the lake, were found to be riverine spawning. Results confirm the occurrence of spatio-temporal segregation in barbs‟ reproduction as previously reported as a mechanism enhancing reproductive isolation between closely related Lake Tana barbs. However, considerable overlap both in space and time of spawning in different barb species recorded in this study indicates that spatio-temporal segregation is far from complete. Breeding behavior of Tana barbs was also studied in nature and in the laboratory. Species-specific differences were revealed in the pre-mating behavior of different barb species. It is proposed that barbs participate in reproductive isolation enhancing the effects of space-temporal segregation. Keywords/phrases: Breeding behavior, Labeobarbus , Lake Tana, Reproductive isolation, Spatio-temporal segregation
Colour Adaptation in Picture-Viewing Situations

AbstractThe chromaticities that appeared neutral were determined for ob ervers adapted to viewing conditions typical for projected transparencies. Neutrality was determincd by a naming technique. Adaptation to the picture area was found to be incomplete, except for colour temperatures in the range 5500 to 6500 K. Neutral points were also determined for a typical television picture with various amounts of ambient tungsten light.