Miracle-dz/UniFAR-FTUs huggingface dataset:
Beef cow weight variations during gestation and offspring performance: a meta-analysis

The objective of this meta-analysis was to evaluate the effects of weight loss or weight gain of beef cows during the second and/or third trimester of gestation on the postnatal performance of the progeny. The variation in cow weight during the gestational period was calculated to standardize the treatments, being them: severe loss (SL = cows that lost more than 10% of weight); moderate loss (ML = cows that lost from 0 to 10% of weight) and weight gain (WG = cows that gained weight). The intensity of the cow weight variation effect was calculated as the mean difference (MD) with a 95% confidence interval and heterogeneity determined using the Q test and the I2 statistic. A meta-analysis of random effects was conducted for each indicator separately with the means of the control and experimental groups. Calves from WG cows were higher for birth weight (P = 0.0094); weight adjusted to 205 days (P = 0.0127) and average daily gain during pre-weaning (P < 0.0001) in relation to calves from ML cows. The W205 of calves from SL cows was 11.6 kg lower than the progeny from ML cows. The post-weaning performance of the progeny tended (P = 0.0868) to be higher in the progeny of WG cows than ML ones. The weight gain of beef cows during gestation improves the pre- and post-weaning performance of the progeny, with more evident effects in the early months of life of the offspring.
Guillain-Barre Syndrome and Antibodies to Arboviruses (Dengue, Chikungunya and Japanese Encephalitis): A Prospective Study of 95 Patients Form a Tertiary Care Centre in Southern India

Objective: The aim of this study was to detect the presence of IgM antibodies against dengue (DEN), chikungunya (CHIK) and Japanese encephalitis (JE) in the serum and CSF of patients with Guillaine-Barre syndrome (GBS). Methods: GBS patients (>12 years of age) were included after informed consent. Data on history, clinical manifestations, treatment details, and outcome were collected. Serum and CSF were tested for IgM antibodies against DEN, CHIK, and JE. Results: From April 2018 to December 2019, 95 patients were included in this study. Anti-arboviral IgM antibodies were detected in 30 patients (31.5%) (CSF 11, serum 13, both CSF and serum 6). Serum IgM antibody was present in 19 patients (JE 8, DEN 5, CHIK 2, more than 1 virus 4). Of the 66 patients who underwent CSF studies, antibodies were present in 17 (CHIK 14, DEN 1, more than 1 virus 2). Antibody positivity did not affect the outcome of GBS. Conclusion: One-third of the GBS patients had evidence of recent infection by arboviruses. This suggests that DEN, CHIK, and JE could be the inciting event for GBS in endemic regions.
The prevention of injuries among youth basketballers according to the “Sequence of Prevention’’: a systematic review

Background: Basketball is played by the youth worldwide, and various injuries occur in youth basketball. There is currently no overview of the incidence, the risk factors and preventive measures of musculoskeletal injuries among youth basketball players. Objective: This systematic review describes the most common injuries among youth basketball players. The most common risk factors and various preventive measures and interventions have also been reported and discussed. Methods: Search strategies were built based on groups of keywords, namely ‘injury’, ‘youth basketball’, and ‘cohort’. Search strategies were entered into Medline and SPORTDiscus. Titles, abstracts and full text articles were screened by two researchers. Data from the included articles were extracted by one researcher and checked by another researcher. Results: Twenty-seven studies showed that the overall injury rate ranged from 2.64 to 3.83 per 1 000 hours of exposure. Ankle- (22%-37%) and knee injuries (5%-41%) were the most common injuries. Risk factors for knee injuries included ankle dorsiflexion with a range less than 36.5 degrees and female athletes with greater hip abduction strength. High variations of postural sway corresponded to occurrences of ankle injuries (p=0.01, OR =1.22; p<0.001, OR =1.22). A core intervention (rate = 4.99/1 000 athlete exposure (AEs)) focused on the trunk and lower extremity led to a reduction in injuries compared to a sham intervention (rate =7.72/1 000 AEs) (p=0.02). Wearing a McDavid Ultralight 195 brace reduced ankle injuries compared to the controls (HR 0.30; 95 % CI 0.17 0.90; p=0.03). Conclusion: Ankle and knee injuries are the most common injuries among youth basketball players. Poor postural control, reduced ankle dorsiflexion and high hip abduction strength are the main risk factors. A neuromuscular warm-up, in combination with strength and stability exercises, seems to be the best training method to prevent injuries. Ankle injuries can be reduced by wearing a lace-up ankle brace.
WOOD VOLUMETRY OF Tachigali vulgaris PURE PLANTATIONS IN DIFFERENT PLANTING SPACINGS

The aim of this study was to develop volumetric equations for tachi-branco trees (Tachigali vulgaris L. G. Silva & H. C. Lima), by assessing the effect of initial planting spacing in volume estimates, as well as developing an equation to estimate the equivalent diameter (deq). Data are from an experiment located in north Pará. The experiment was conducted with the randomized blocks design, being three blocks with six treatments each. The most used volumetric models were assessed for two distinct situations: considering each trunk as a tree and using the tree deq as independent variables in the volumetric model. The need for individual equations for initial planting spacing was tested. In addition, an equation for deq estimate was proposed. The use of deq provided more precise and accurate volumetric estimates regarding diameter at breast height. Among the models tested, the Schumacher-Hall model was selected. Through the model identity test, the equation can be used to estimate tree volume of Tachigali vulgaris, regardless of planting spacing. The equivalent diameter can be estimated via equation from minimum and maximum diameters of tree trunks. The maximum percentage differences of volume by hectare obtained with the measurement of all trunks and deq were only 5% without loss in production accuracy per unit of area
Role of Orai3 in the Pathophysiology of Cancer

The mammalian exclusive Orai3 channel participates in the generation and/or modulation of two independent Ca2+ currents, the store-operated current, Icrac, involving functional interactions between the stromal interaction molecules (STIM), STIM1/STIM2, and Orai1/Orai2/Orai3, as well as the store-independent arachidonic acid (AA) (or leukotriene C4)-regulated current Iarc, which involves Orai1, Orai3 and STIM1. Overexpression of functional Orai3 has been described in different neoplastic cells and cancer tissue samples as compared to non-tumor cells or normal adjacent tissue. In these cells, Orai3 exhibits a cell-specific relevance in Ca2+ influx. In estrogen receptor-positive breast cancer cells and non-small cell lung cancer (NSCLC) cells store-operated Ca2+ entry (SOCE) is strongly dependent on Orai3 expression while in colorectal cancer and pancreatic adenocarcinoma cells Orai3 predominantly modulates SOCE. On the other hand, in prostate cancer cells Orai3 expression has been associated with the formation of Orai1/Orai3 heteromeric channels regulated by AA and reduction in SOCE, thus leading to enhanced proliferation. Orai3 overexpression is associated with supporting several cancer hallmarks, including cell cycle progression, proliferation, migration, and apoptosis resistance. This review summarizes the current knowledge concerning the functional role of Orai3 in the pathogenesis of cancer.
A Control Method of SOFC-based DC Micro-grid to Avoid Fuel Starvation when External Load Power Increases

At present, the direct current (DC) micro-grid based on the solid oxide fuel cell (SOFC) can supply the power to the external load independently. Despite an adequate and steady supply of the electricity to the external load, the high efficiency and avoiding fuel starvation is other points for the attention. In this paper, a control method of the SOFC-based DC micro-grid has been proposed, which can avoid the fuel starvation when the external load power increases This method adopts the optimal operating points (OOPs) to obtain the maximum efficiency, and then a novel time-delay control algorithm based on the system electric current is designed to avoid the fuel starvation. All simulation results demonstrate that the proposed method is feasible, which can effectively solve the fuel starvation problem. What's more, the output efficiency can be up to 40%, which can get the high efficiency of the power supply. The works in this paper can provide the reference for other similar systems to solve the fuel starvation problem.
The Effect of Different Dietary and Therapeutic Solutions on the Color Stability of Resin-Matrix Composites Used in Dentistry: An In Vitro Study

The purpose of this study was to evaluate the color stability of aesthetic restorative resin-matrix materials after their immersion in different dietary and therapeutic solutions. Thirty disc-shaped specimens (10 × 2 mm) were prepared from three different types of resin-matrix composites used in dentistry (BE, FS, AF). The color coordinates (L*a*b*, ΔL*, Δa*, Δa*, Δb* and ΔE*) were measured using a VITA Easyshade 3D-Master (VITA Zahnfabrik, Bad Säckingen, Germany) before and after the immersion of the specimens in coffee, red wine, Coca-Cola®, Eludril Care®, and distilled water solutions for 40 h. The color change (ΔE*) was calculated and analyzed by the Kolmogorov -Smirnov test and the Kruskal -Wallis multiple-comparison test. All the restorative materials showed significant color (ΔE*) changes after their exposure to red wine, followed by coffee and Coca-Cola®; however, one nanohybrid resin-matrix composite showed a high color stability in such colored test solutions. The chemical composition and content of the organic matrix played a key role in the color stability of the resin-matrix composites. Clinicians should advise their patients about the chemical interaction between dietary substances and different resin-matrix composites.
A Systematic Literature Review of Quality Management Initiatives in Dental Clinics

By considering the recently proposed definitions and metrics, oral healthcare quality management (OHQM) emerges as a distinct field in the wider healthcare area. The goal of this paper is to systematically review quality management initiatives (QMIs) implementation by dental clinics. The research methodology approach is a review of 72 sources that have been analyzed using the Context–Intervention–Mechanism–Outcome Framework (CIMO). The analysis identifies five mechanisms that explain how quality management initiatives are implemented by dental clinics. The simplest QMIs implementations are related to (1) overall quality. The next ones, in terms of complexity, are related to (2) patient satisfaction, (3) service quality, (4) internal processes improvement, and (5) business outcomes. This paper is the first attempt to provide a critical review of this topic and represents an important advancement by providing a theoretical framework that explains how quality management is implemented by practitioners in this field. The results can be used by scholars for advancing their studies related to this emerging research area and by healthcare managers in order to better implement their quality management initiatives.
Plasmonics

The rapid development of graphene has opened up exciting new ﬁelds in graphene plasmonics and nonlinear optics. Graphene’s unique two-dimensional band structure provides extraordinary linear and nonlinear optical properties, which have led to extreme optical conﬁnement in graphene plasmonics and ultrahigh nonlinear optical coefﬁcients, respectively. The synergy between graphene’s linear and nonlinear optical properties gave rise to nonlinear graphene plasmonics, which greatly augments graphene-based nonlinear device performance beyond a billion-fold. This nascent ﬁeld of research will eventually ﬁnd far-reaching revolutionary technological applications that require device miniaturization, low power consumption and a broad range of operating wavelengths approaching the far-infrared, such as optical computing, medical instrumentation and security applications.
NR4A3: A Key Nuclear Receptor in Vascular Biology, Cardiovascular Remodeling, and Beyond

The mechanisms committed in the activation and response of vascular and inflammatory immune cells play a major role in tissue remodeling in cardiovascular diseases (CVDs) such as atherosclerosis, pulmonary arterial hypertension, and abdominal aortic aneurysm. Cardiovascular remodeling entails interrelated cellular processes (proliferation, survival/apoptosis, inflammation, extracellular matrix (ECM) synthesis/degradation, redox homeostasis, etc.) coordinately regulated by a reduced number of transcription factors. Nuclear receptors of the subfamily 4 group A (NR4A) have recently emerged as key master genes in multiple cellular processes and vital functions of different organs, and have been involved in a variety of high-incidence human pathologies including atherosclerosis and other CVDs. This paper reviews the major findings involving NR4A3 (Neuron-derived Orphan Receptor 1, NOR-1) in the cardiovascular remodeling operating in these diseases.
Method Validation and Characterization of the Associated Uncertainty for Malondialdehyde Quantification in Exhaled Breath Condensate

There are several methods for quantifying malondialdehyde (MDA), an oxidative stress biomarker, in exhaled breath condensate (EBC). However, due to the very diluted nature of this biological matrix, a high variability is observed at low concentrations. We aimed to optimize a 2,4-dinitrophenylhydrazine-based method using liquid chromatography coupled to tandem mass spectrometry and characterize the uncertainty associated with this method. We investigated the following parameters for the method validation: calibration linearity, limit of detection (LOD), precision, recovery, and matrix effect. The results were used to identify the main sources of uncertainty and calculating the combined uncertainty. The applicability of this method was evaluated in an ongoing epidemiological study by analyzing 164 EBC samples collected from different professional groups in subway environments. The optimized method was sensitive (LOD: 70 pg/mL), precise (inter-day variation < 19%) and accurate (recovery range: 92–106.5%). The calculated analytical uncertainty was the highest at the LOQ level and reached 23%. Although the analytical uncertainty was high at low MDA concentrations, it was significantly lower than that the observed inter-individual variability. Hence, this method performs sufficiently well and can be recommended for future use in epidemiological researches relying on between-subject differences.
Prevalence, Phylogroups and Antimicrobial Susceptibility of Escherichia coli Isolates from Food Products

The emergence of multi-drug resistant E. coli is an important matter of increasing considerable concern to global public health. The aim of this study was to investigate the incidence, antibiotic resistance pattern and phylogroups of E. coli isolates obtained from raw milk, vegetable salad and ground meat samples collected from Qazvin Province (Iran). Culture-based techniques, Kirby-Bauer disk diffusion susceptibility testing and PCR assays were used to determine the incidence rate, antimicrobial resistance pattern and phylogenetic groups of the E. coli isolates. The E. coli isolates were highly resistant to amoxicillin (79.1%), trimethoprim-sulfamethoxazole (70.8%), amoxicillin-clavulanic acid (62.5%), tetracycline (54.1%), chloramphenicol (54.1%), nitrofurantoin (54.1%), ampicillin (45.8%), streptomycin (45.8%), and kanamycin (33.3%); and completely susceptible to norfloxacin and azithromycin and 70.8% of the isolates were multi-drug resistant. Most E. coli isolates (46%) belonged to phylogroup A. Novel, practical, efficient food safety control and surveillance systems of multi-drug resistant foodborne pathogens are required to control the foodborne pathogen contamination.
Impact of resilience on the health‐related quality of life of adolescents with a chronic health problem AS PER PDF: A structural equation approach Resilience and health‐related quality of life of adolescents AS PER PDF

AIM The aim of this study was to test the impact of resilience on the health-related quality of life among adolescents with a chronic health problem, we established a structural model to explain patients' health-related quality of life. BACKGROUND There are various resilience-related factors with major effects on the health-related quality of life among adolescents with a chronic disease; however, little is known about relationships among resilience, these influencing factors and direct and indirect effects of health-related quality of life among adolescents with a chronic health problem. DESIGN This study adopted a cross-sectional, descriptive correlational design. METHODS Participants were 220 adolescents with a chronic disease who were aged between 10 and 18 years and currently receiving treatment at a hospital or clinic for least 6 months from February to October 2017 in Korea. RESULTS This study verifies that hope and courageous coping had direct effects on the resilience of adolescents with a chronic health problem and the level of direct effects on health-related quality of life was in the following order: hope, resilience and courageous coping. In addition, illness-related distress, social support, hope and defensive coping had indirect effects on resilience and the level of indirect effects on health-related quality of life was in the following order: illness-related distress, social support, defensive coping, hope and courageous coping. CONCLUSION Resilience is a major factor that improves health-related quality of life among adolescents with a chronic health problem. In consideration of the direct and indirect paths verified through this study, it is necessary to develop interventions to improve health-related quality of life among adolescents with a chronic health problem.
Effects of different inorganic anions on equipment material corrosion behaviour in subcritical water oxidation

In this work, possible corrosion mechanisms of Fe- and Ni-based alloys are discussed which are protected by Cr2O3, NiO and MoO2 surface layers. But chloride ions can dissolve these oxide films and there is a strong synergistic effect between hydronium ions and oxygen, leading to severe local alloy corrosion. On the other hand, titanium and Zr-3 alloys show good corrosion resistance in acidic oxidising subcritical water containing different inorganic salts. A double-layer oxide film (TiO and TiO2) is formed on the surface of TA2 and TA9 alloys, while a triple oxide layer (TiO, Ti2O3 and TiO2) is formed on TA10 surfaces in such aqueous solutions containing chloride and sulphate ions. In addition to the two oxide layers, Ti3(PO4)4 deposits are also formed on the surface of TA2 and TA9 alloys when the subcritical water contains phosphates. Moreover, (TiO)2P2O7 deposits form besides Ti3(PO4)4 layers on the surface when the TA10 alloy is oxidised under the latter conditions.
Wound healing by topical application of Momordica charantia L. formulations on mice

Abstract Background and Aim: Momordica charantia is mainly characterized by its antimicrobial and antioxidant properties. The current study aimed to evaluate the healing activity of gel and cream formulations based on M. charantia on induced wounds in mice. Materials and Methods: Acetonic extract of M. charantia was prepared and incorporated into gel and cream formulations. Mus musculus Balb/c (n=30) with induced injury were distributed into five groups: Group I (control – day 7), Group II (control – day 14), Group III (1% gel – day 7), and Group IV (1% gel – day 14) to which 1% M. charantia gel was dermally applied daily for 7 and 14 days, respectively, Group V (1% cream – day 7) and Group VI (1% cream – day 14) to which of M. charantia 1% cream were dermally applied daily for 7 and 14 days, respectively. Time of wound closure was determined during the experimentation; rats were euthanized with sodium pentobarbital 60 mg/kg/pc v.ip. for obtaining skin samples for histopathological analysis. Results: Groups IV and VI showed a higher percentage of wound closure on day 14, and in histopathological analysis, effect was greater in Group VI with the presence of fibroblasts and abundant collagen and elastic fibers. Conclusion: M. charantia gel and cream showed wound healing activity on induced wounded mice; the most effective treatment was M. charantia 1% cream formulation.
Calcium silicate enhances immunosuppressive function of MSCs to indirectly modulate the polarization of macrophages

Abstract Bioactive silicate ceramics (BSCs) have been widely reported to be able to induce bone tissue regeneration, but the underlying mechanisms have not been fully elucidated. Previous studies have reported that ionic products of BSCs can promote bone regeneration by directly simulating osteogenic differentiation of mesenchymal stem cells (MSCs) and modulating the polarization of macrophages to create a favorable inflammation microenvironment for initiating bone regeneration cascades. However, the immunomodulatory ability of MSCs also plays a critical role in bone regeneration but the effects of BSCs on the immunomodulatory ability of MSCs have been rarely investigated. This study aims to investigate the effects of ionic products of BSCs on the immunoregulatory ability of MSCs to further understand the mechanism of BSCs enhancing bone regeneration. Results showed that ionic products of calcium silicate (CS), one of the representative BSCs, could enhance the immunosuppressive function of human bone marrow mesenchymal stem cells (HBMSCs) by up-regulating the expression of immunosuppressive factors in HBMSCs via NF-κB pathway. In addition, CS-activated HBMSCs showed stronger stimulatory effects on M2 polarization of macrophages than CS ionic products. Furthermore, the macrophages educated by CS-activated HBMSCs showed stronger stimulatory effects on the early osteogenic differentiation of HBMSCs than the ones regulated by CS ionic products. These results not only provide further understanding on the mechanism of BSCs enhancing bone regeneration but also suggest that it is critical to consider the effects of biomaterials on the immunomodulatory function of the tissue forming cells when the immunomodulatory function of biomaterials is investigated.