Miracle-dz/UniFAR-FTUs huggingface dataset:
Meat and Muscle BiologyTM Effects of Increased Pork Hot Carcass Weights. II: Loin Quality Characteristics and Palatability Ratings1,2

The objective of this study was to evaluate the effects of increased pork hot carcass weight on loin quality and palatability of top loin chops. Pork loins (N = 200) were collected from 4 different hot carcass weight groups: A light weight (LT; less than 111.8 kg), medium-light weight (MLT; 111.8 to 119.1 kg), medium-heavy weight (MHVY; 119.1 to 124.4), and a heavyweight group (HVY; 124.4 and greater). Following fabrication, chops were assigned to fat and moisture analysis, Warner-Bratzler shear force (WBSF), consumer sensory panels, or trained sensory panels. Chops from the HVY group were rated as more (P < 0.05) tender compared to chops from the LT carcasses. Additionally, chops from the HVY weight group had greater (P < 0.05) consumer overall like ratings compared to chops from both the LT and MLT groups. Carcass weight did not affect (P > 0.05) consumer flavor liking ratings. Hot carcass weight treatment did not contribute (P > 0.05) to the percentage of chops rated acceptable for flavor and overall liking. The greatest (P < 0.05) percentage of samples were rated acceptable for juiciness for chops from the HVY weight group, and the lowest (P < 0.05) percentage of acceptable ratings for tenderness were for chops from the LT weight group. Both initial and sustained juiciness from MHVY carcasses were rated as more (P < 0.05) juicy compared to chops from both MLT and LT carcasses by trained sensory panelists. Additionally, chops from the LT carcasses had the lowest (P < 0.05) myofibrillar tenderness ratings. Chops from MHVY and HVY carcasses were similar (P > 0.05), with greater (P < 0.05) overall tenderness ratings compared to chops from LT carcasses. These results indicate chops from heavier weight carcasses may have improved tenderness and juiciness compared to chops from lighter carcasses.
The Evolution of Industrial Agglomerations and Specialization in the Yangtze River Delta from 1990–2018: An Analysis Based on Firm-Level Big Data

Although industrial agglomeration and specialization have been studied for more than 100 years, it is still a controversial field. In the era of big data, it is of great significance to study industrial agglomeration and regional specialization by using firm-level data. Based on 3,053,024 pieces of firm-level big data, the spatial evolution and spatial patterns of industrial agglomeration and specialization of 9 major industries in the Yangtze River Delta, China were revealed. Results show that: (1) the degree of industrial agglomeration is highly related to industrial attributes; industries which are directly related to production tend to be geographically concentrated, while industries that serve for production tend to be spatially dispersed; (2) the evolution characteristics and trajectories of industrial agglomeration vary by industries: wholesale and retail trade and real estate are becoming more spatially dispersed; information industries, leasing and commercial services, scientific research and polytechnic services, as well as finance are experiencing continuous spatial agglomeration; construction and manufacturing show a tendency of transfer from spatial agglomeration to spatial dispersion; (3) since 1990, most industries in the Yangtze River Delta have formed distinct spatial patterns of industrial specialization. Most core cities have experienced obvious deindustrialization processes; and high-end industries are clustering to the three biggest core cities of Shanghai, Nanjing, and Hangzhou.
Improves in external and internal egg quality of Japanese quail (Coturnix coturnix japonica) by giving lactic acid bacteria as alternative antibiotic growth promoter

Background and Objectives: An experiment was designed to determine the effect of using lactic acid bacteria as alternative antibiotic growth promoters on external and internal quality of egg’s Coturnix coturnix japonica. Materials and Methods: Coturnix coturnix japonica (n=240, 14 weeks of age) were randomly distributed into six treatment groups. The treatments were P0 (free antibiotic feed), P1 (free antibiotic feed with 1 gram antibiotic growth promoters (AGP)/100kg feed), P2 (free antibiotic feed with 5 gram probiotic/100kg feed), P3 (free antibiotic feed with 10 grams probiotic/100kg feed), P4 (free antibiotic feed with 5 gram probiotic/200L drinking water), and P5 (free antibiotic feed with 10 gram probiotic/200L drinking water). Probiotic contained Lactobacillus casei (L. casei) and Lactobacillus rhamnosus (L. rhamnosus) culture (1.2 × 108 CFU/gram). To assess the quality parameters, twenty eggs were randomly collected from each treatment at the end of the experimental period, and the data were analysed using one way Anova. Results: Results of the external quality indicated that egg’s weight, length, and width, along with the shell weight and thickness were significantly different (P<0.05) after treatment. Likewise, the results of internal egg quality indicated that yolk color, height, width, and length, together with the albumen height, width, length, index and haugh unit were significantly different (P <0.05) after treatment. Conclusion: It was concluded from this research that dietary supplementation with probiotic which contains L. casei and L. rhamnosus could be used in laying Japanese quail with benefit on external and internal egg quality.
Histogram Analysis and Visual Heterogeneity of Diffusion-Weighted Imaging with Apparent Diffusion Coefficient Mapping in the Prediction of Molecular Subtypes of Invasive Breast Cancers

Objective To investigate if histogram analysis and visually assessed heterogeneity of diffusion-weighted imaging (DWI) with apparent diffusion coefficient (ADC) mapping can predict molecular subtypes of invasive breast cancers. Materials and Methods In this retrospective study, 91 patients with invasive breast carcinoma who underwent preoperative magnetic resonance imaging (MRI) with DWI at our institution were included. Two radiologists delineated a 2-D region of interest (ROI) on ADC maps in consensus. Tumors were also independently classified into low and high heterogeneity based on visual assessment of DWI. First-order statistics extracted through histogram analysis within the ROI of the ADC maps (mean, 10th percentile, 50th percentile, 90th percentile, standard deviation, kurtosis, and skewness) and visually assessed heterogeneity were evaluated for associations with tumor receptor status (ER, PR, and HER2 status) as well as molecular subtype. Results HER2-positive lesions demonstrated significantly higher mean (p=0.034), Perc50 (p=0.046), and Perc90 (p=0.040), with AUCs of 0.605, 0.592, and 0.652, respectively, than HER2-negative lesions. No significant differences were found in the histogram values for ER and PR statuses. Neither quantitative histogram analysis based on ADC maps nor qualitative visual heterogeneity assessment of DWI images was able to significantly differentiate between molecular subtypes, i.e., luminal A versus all other subtypes (luminal B, HER2-enriched, and triple negative) combined, luminal A and B combined versus HER2-enriched and triple negative combined, and triple negative versus all other types combined. Conclusion Histogram analysis and visual heterogeneity assessment cannot be used to differentiate molecular subtypes of invasive breast cancer.
Research on the Productivity Effect of Inter-Regional Industry Transfer—Taking Guangdong Province as an Example

This paper empirically tests the influence of the inter-regional industrial transfer policy which was promoted by local government in Guangdong Province in 2005 on total factor productivity by using the double-difference and triple-difference models, based on the panel data of 120 counties in 21 prefecture-level cities in Guangdong Province from 2001 to 2016. The study found that the inter-regional industrial transfer policy of Guangdong Province has increased the total factor productivity of the area with industry transferring out, but has a negative impact on the TFP of the land with industry transferring in, and there are differences in the effects of total factor productivity in the four regions: the periphery of the Pearl River Delta, Eastern Guangdong, Western Guangdong, and Northern Guangdong. And the industrial transfer has the greatest negative effect on the eastern Guangdong region, and the least negative effect on the western Guangdong, which has a positive impact on the TFP in northern Guangdong. Through further analysis of single factor productivity, the study found that the decline in total factor productivity of the industry is mainly caused by the decline in capital productivity. The experience of inter-regional industrial transfer in Guangdong Province has implications for China’s ascendant inter-regional industrial transfer. How to encourage the government to play a more active guiding role in promoting industrial transfer, promote the increase of total factor productivity and achieve sustainable and stable economic development, is a question worthy of further discussion.
Efficacy of a single fixed 131I dose of Radioactive iodine for the treatment of hyperthyroidism

A total of 135 patients were treated for hyperthyroidism with 131I 15 mCi radioiodine ablation. The therapeutic target was achieving hypothyroidism. Between January 2014 and December 2018, clinical records were reviewed and the data was collected and reviewed for 135 patients with hyperthyroidism that were referred to the Nuclear Medicine Department at Salmaniya Medical Center, for Radioactive Iodine (RAI) thyroid gland ablation procedure for definitive treatment of hyperthyroidism. About 39.7% of our patients achieved response between 4-6 months out of which 35.7% of the patients showed response in the first 3 months. 21.4% of the patients took between 7-12 months to show response and only 3.2% responded after 12 months. The most significant response was hypothyroidism comprising of 94.4%. It is also worth mentioning that 4.0% of patients achieved euthyroidism and did not require any followup medication. Using a fixed dose of RAI of 15mCi for treating various types of Hyperthyroidism, successful treatment with a single dose of RAI can be achieved in 92.7% of the patients, with first therapy failure rate in 7.3%, with few patients requiring additional doses of RAI.
Characterization of lactobacilli strains isolated from baby’s feces for their potential immunobiotic application

Background and Objectives: Several LAB species were evaluated and characterized for potential probiotic use. Besides the antimicrobial activity, probiotics showed recently a capacity to prevent and to alleviate inflammatory and chronic diseases. Immunomodulation effect is one of the modes of actions of such probiotics, called immunobiotics, which can be used in several chronic diseases such as Inflammatory Bowel Diseases (IBD). The aim of this study was to isolate, identify and characterize lactobacilli strains from healthy baby’s feces in order to select some strains with potential immunobiotic application especially strains which can stimulate anti-inflammatory responses. Materials and Methods: Forty-two LAB strains were isolated and identified by the MALDI-TOF / MS technique. In addition, strains were subjected to several assessments such as antimicrobial activity, the capacity to form biofilm in polystyrene microplate and immunomodulation activity in a PBMC model. Results: Results showed that the majority of strains (90.4%) were identified as Lactobacillus. However, among these, only 39.4% of lactobacilli strains were not identified at the species level. All isolated lactobacilli strains showed an anti-inflammatory effect. Moreover, 7 strains were considered as good probiotic candidates based on their characteristics such as their antibacterial activities, formation of the strongest biofilm and their ability to stimulate an anti-inflammatory response in PBMCs model. Conclusion: Two strains (Lactobacillus spp S14 and Lactobacillus spp S49) which showed the best immunobiotic characteristics, could be selected and evaluated more deeply in vivo model as well as in human clinical study to ensure their effectiveness in inflammatory diseases such as IBD.
Oocytes Development in the Fry of Blue Gourami, Trichogaster trichopterus

In this study, we examined the first period of ovarian development as well as the levels of Estradiol-17β (E2) and gonadal CYP19 (bgCYP19a) in blue gourami, Trichogaster trichopterus. Samples of larvae were taken 38, 55 and 80 days after hatching for histological examination. In the ovary of 38 days larvae, the number of oocytes and ovary size were small. On day 80 after hatching, the number of oocytes increased. On day 38 after hatching, all the oocytes were in the perinuclear stage. This stage did not change on day 80, but very few oocytes did change. In several oocytes, there is brining of granulose continuous vitelline which indicates the start of vitellogenesis. The mRNA expression of the bgCYP19a gene was detected by using real-time PCR (TPCR) in the tissues of 38and 80days larvae after hatching. The level decreased insignificantly from day 38 to day 80. The E2 increased significantly in larvae at the age of 80 days compared to larvae at the age of 38 days.
Psychological determinants of pre-hypertension among first year undergraduate students in a public university in Malaysia

Pre-hypertension increased the risk of morbidity and mortality from non-communicable diseases. Whereas, psychological factors such as depression, anxiety and stress have been associated with increased in blood pressure. However, previous studies more focuses on psychological determinants of hypertension than prehypertension. Thus, this study aims to determine the association between these psychological factors with pre-hypertension. A cross-sectional study was conducted in 2012 among first year students of a public Malaysian university. A random cluster sampling was used to select 5 out of 15 faculties and a total of 495 students participated in this study. The Malay version of DASS-21 was used to elicit their levels of depression, anxiety and stress. Blood pressures were measured twice using sphygmomanometer and the averages were taken. Data analyses used chi-square test and binary multiple logistic regression. The prevalence of pre-hypertension was 30.1%. The percentage of severe and extremely severe depression was 3.8% and 1.2%; both severe and extremely severe anxiety was 16.4%; and severe and extremely severe stress was 4.2% and 0.2% respectively. Severe/extremely severe depression had more than 3 times higher in getting pre-hypertension than no depression. In conclusions, almost one third of respondents had pre-hypertension and only severe/extremely depression was associated with pre-hypertension.
Visual evoked potentials: Impact of age, gender, head size and BMI

Background and Objectives: Pattern-reversal visual evoked potential (PRVEP) is an objective, sensitive and non-invasive neurophysiological test that can prove to be a useful clinical tool in investigating the physiology and pathophysiology of human visual system. A successful clinical application of the test, however, is not possible without the acquisition of a normative data adjusted to known confounding physiological variables. Hence, this study attempted to obtain PRVEP values in different age-groups and gender in healthy adults and also to find out the influence of head size and body mass index on PRVEP parameters. Methods: PRVEP was recorded in 52 healthy adults in the age-group of 18-70 years. PRVEP parameters were compared in different age-groups and gender using one way ANOVA. Head size and BMI were correlated with PRVEP parameters by Pearson correlation coefficient and the significance of difference analysed. Results: The study demonstrated statistically significant differences in mean P100 latency among various age-groups. Gender difference revealed statistical significant difference in both the PREVP parameters (P100 latency and N75-P100 amplitude). The correlation of head size and BMI with PRVEP parameters could not be found to be statistically significant. Conclusion: Clinical interpretation of PRVEP should be based on age and sex matched normal subjects besides standardizing the technical parameters of the laboratory. This study also suggests that endocrinal differences should be borne in mind besides the anatomical differences for gender variation in PRVEP-P100 latency.
MiR-449a regulates the cell migration and invasion of human non-small cell lung carcinoma by targeting ADAM10

Background: MicroRNAs (miRNAs) are non-coding small RNAs that have been shown to play a key role in the development of many tumors. However, its speci ﬁ c mechanism of action in non-small cell lung cancer (NSCLC) is not very clear. Purpose: This study was to identify the effect of miRNA-449a on NSCLC invasion and migration. Methods: We used quantitative real-time PCR experiments to demonstrate that miRNA-449a is down-regulated in NSCLC tissues and cell lines. We also used the Transwell assay to detect cell invasion and migration, and the Western Blot assay was used to detect protein expression. The dual luciferase assay was used to detect the targeting relationship between miR-449a and A Disintegrin And Metalloproteinases 10 (ADAM10). Results: Our experiments demonstrated that miRNA-449a was down-regulated in NSCLC tissues and cell lines. When miRNA-449a was up-regulated in NSCLC cells, the invasion and migration ability of the cells was weakened, and the expression of ADAM10 was decreased. After down-regulation of miRNA-449a, the cell ’ s invasion and migration ability was enhanced, and the expression of ADAM10 was increased. Through dual luciferase assays, we also found that miRNA-449a can target ADAM10 to delay the progression of epithelial-mesenchymal transition (EMT) and inhibit invasion and migration. Conclusion: Our experiments demonstrated that miRNA-449a acted as a tumor suppressor gene through inhibiting the expression of ADAM10 in NSCLC.
Study on MAP process at laboratory scale for the removal of NH4-N

-This laboratory scale study was conducted on the MAP process to improve struvite precipitation and more efficient removal of NH4-N from the wastewater. MAP process is one of the innovative Physico-chemical processes which can majorly contribute for the removal of NH4-N by forming the struvite complex under required condition. In order to meet stringent discharge standards for NH4-N, an experimental work was carried out focusing the general problem of effluent discharge for the industries of India containing high NH4-N stream. For this we evaluated the effort of feeding sequence of precipitating reagent (lime, flocculent, magnesium and phosphate) for NH4-N removal by forming MAP i.e. struvite deposit keeping calcium interference in mind. Various studies reviewed which effectively precipitate struvite by an addition of excess magnesium and phosphate sources with different stoichiometric ratios. The stoichiometric calculation for the optimized dosage of reagent makes the precipitation more efficient. Different stoichiometric ratio were tested to determine the required Mg and PO4 3+ concentration for maximum NH4N removal by keeping NH4 + constant for the effluent and kinetics of struvite formation was studied. Keywords-Ammoniacal Nitrogen, struvite precipitation, MAP
Effect of resistance inducers on in vitro inhibition of mycelial growth and sporulation of Fusarium solani causing root rot of fenugreek

Fenugreek is a leafy vegetable plant known for its medicinal, pharmaceutical and nutraceutical properties. The root rot of fenugreek is more severe in recent years. Controlling this disease depends mainly on use of fungicides. The use of resistance inducers is an effective and nonfungicide alternative with antimicrobial properties and also induces resistance in plant. All isolates of Fusarium solani had potency to cause root rot disease but the isolate from Jaygaon locality was found highly virulent one and was selected for in vitro studies. The inhibitory effect of plant resistance inducers viz. chitosan (1-15 mg/ml), methyl jasmonate (1-20 mM) and salicylic acid (2080 mM) on linear growth and sporulation of F. solani was evaluated by poisoned food technique. The obtained results showed that chitosan had significantly reduced linear growth and sporulation of F. solani with increase of concentrations when compared to control. The complete inhibition of both linear growth and sporulation was observed at 15 mg/ml and 10 mg/ml concentrations respectively. Methyl jasmonate (MeJa) had also significantly reduced linear growth in a concentration dependent manner. The highest fungal growth reduction (76.37 %) was observed with 20 mM concentration. It was interesting that MeJa had halted spore formation of fungus at10 mM concentration. The increasing concentrations (20, 40 and 60 mM) of salicylic acid (SA) were found to promote linear growth. However, 80 mM of SA had totally suppressed the growth of fungus. But, reduction of sporulation was found as SA concentrations increased over control. The results of current study showed the possibility of using resistance inducers to control Fusarium root rot of fenugreek.
Game-Based Learning With Direct Representation of Mathematics

Symbolic representations in mathematics (e.g., equations) are powerful and essential for more advanced mathematical thinking, but they cause major problems for K–8 learners. To engage mathematical reasoning without symbolic representations, BrainQuake has created diagrammatic mathematics puzzle games that provide an alternative, more learner-friendly interface to mathematical thinking and multistep problem solving. In this working paper, we first outline the design underlying BrainQuake’s puzzle games, and we provide preliminary evidence that they can be used effectively in classroom settings. The latter part of this paper outlines a randomized control study—currently in progress—examining how BrainQuake’s suite of puzzle games impacts students’ mathematics achievement and attitudes. The results of the randomized trial will be presented at the conference. This work on the whole provides a concrete illustration of how understanding of deeper cognitive processing can be leveraged to design learning games that effectively support students in reasoning in mathematics.
Numerical Simulation of a Pitching Airfoil Under Dynamic Stall of Low Reynolds Number Flow

In this research, viscous, unsteady and turbulent fluid flow is simulated numerically around a pitching NACA0012 airfoil in the dynamic stall area. The Navier-Stokes equations are discretized based on the finite volume method and are solved by the PIMPLE algorithm in the open source software, namely OpenFOAM. The SST k - ω model is used as the turbulence model for Low Reynolds Number flows in the order of 105. A homogenous dynamic mesh is used to reduce cell skewness of mesh to prevent non-physical oscillations in aerodynamic forces unlike previous studies. In this paper, the effects of Reynolds number, reduced frequency, oscillation amplitude and airfoil thickness on aerodynamic force coefficients and dynamic stall delay are investigated. These parameters have a significant impact on the maximum lift, drag, the ratio of aerodynamic forces and the location of dynamic stall. The most important parameters that affect the maximum lift to drag coefficient ratio and cause dynamic stall delaying are airfoil thickness and reduced frequency, respectively.