Miracle-dz/UniFAR-FTUs huggingface dataset:
Tactile Texture Rendering for Electrostatic Friction Displays: Incorporation of Low-Frequency Friction Model and High-Frequency Textural Model

Tactile texture presentation on touch panels enhances their usability and realizes immersive user interfaces. This study develops a tactile texture rendering method for electrostatic friction displays. The method combines two rendering models for material textures compared with previous studies which focused on either of these two models. One of these models is a physical model that simulates low-frequency frictional signals depending on the exploratory finger velocities and contact loads. The other is an autoregression-based data-driven model for high-frequency textural friction. For user studies, we compared combining the two models with using only the physical model for the four types of materials. Although the effectiveness varied across the materials, the subjectively judged realism and identification of the materials were improved for the combined condition. The new method combining high-frequency textural information and low-frequency physical model-based friction is expected to provide realistic tactile textures for electrostatic surface tactile displays.
Influence of electrodes and Bragg reflector on the quality of thin film bulk acoustic wave resonators

It is considered that the acoustic wave attenuation in the metal and piezoelectric films, the wave scattering loss, and the electrode electrical loss are the possible quality factor detractors in FBAR devices. Due to the small acoustic wave attenuation of the Mo electrode, the composite Mo-AlN-Mo resonator with thick electrodes provides higher Q than that with thin Mo electrodes. In such Mo electroded resonators, a relatively high effective coupling coefficient is retained. In Q value detractors, the acoustic wave scattering loss originating from surface roughness is thought to be fatal in terms of FBAR quality. The thickness of the low impedance SiO/sub 2/ layer of the Bragg reflector also affects the Q value and effective coupling constant due to the low material Q of the SiO/sub 2/ film.
An Artificial Intelligence–Based Chest X-ray Model on Human Nodule Detection Accuracy From a Multicenter Study

Key Points Question Can artificial intelligence (AI) improve detection of pulmonary nodules on chest radiographs at different levels of detection difficulty? Findings In this diagnostic study, AI-aided interpretation was associated with significantly improved detection of pulmonary nodules on chest x-rays as compared with unaided interpretation of chest x-rays. Meaning These results suggest that an AI algorithm may improve diagnostic performance of radiologists with different levels of experience for detecting pulmonary nodules on chest radiographs compared with unaided interpretation.
Safety and immunogenicity of BNT162b2 mRNA COVID-19 vaccine in Japanese patients after allogeneic stem cell transplantation.

Patients who have undergone hematopoietic stem cell transplantation (HSCT) for hematological disease experience high mortality when infected by coronavirus disease 2019 (COVID-19). However, the safety and efficacy of COVID-19 vaccine in HSCT patients remains to be investigated. We prospectively evaluated the safety and immunogenicity of BNT162b2 mRNA COVID-19 vaccine (Pfizer BioNTech) in 25 Japanese allogeneic HSCT patients in comparison with 19 healthy volunteers. While anti-S1 antibody titers in almost all healthy volunteers after the second dose were higher than the cut-off value reported previously, levels in HSCT patients after the second dose were diverse. Nineteen patients (76%) got seroconversion of anti-S1 IgG. Median optical density of antibody levels in HSCT patients with low IgG levels (< 600 mg/dL), steroid treatment, or low lymphocytes (< 1000 /L) was significantly lower than that in the other HSCT patients. There were no serious adverse events (> Grade 3), no new development or exacerbation of graft-versus-host disease after vaccination. We concluded BNT162b2 mRNA vaccine is safe and effective in Japanese allogeneic HSCT patients.
SARS-CoV-2 Omicron variant: healthcare workers' perceptions and beliefs of vaccine effectiveness and advocacy: a national survey during the first week of the World Health Organization variant alert

Background: As COVID-19 Omicron variant spread in several countries, healthcare workers' (HCWs) perceptions of vaccine effectiveness, booster and worries warrant reassessment. Methods: Online questionnaire among HCWs in Saudi Arabia (KSA) was collected between Dec 1-6, 2021, aiming to assess their Omicron variant's perceptions, worries, and booster-vaccine advocacy. Results: Among the 1285 HCWs participants in the study, two-thirds were females, 41% were nurses,46.4% were physicians, and 50% worked in tertiary care hospitals. Vaccination was perceived to be the most effective way to prevent the spread of Omicron variant and future variants by 66.9%. The respondents perceived social distancing (78%), universal masking (77.8%), and avoiding unnecessary travel (71.4%), slightly superior to vaccination to prevent COVID-19 variants spread. Of the respondents, 99.5% received two doses of COVID-19 vaccine. Regarding the booster dose, 96% either received it or planned to receive it once they are eligible. 57.7% of the respondents agreed that Omicron could cause a new COVID-19 wave worldwide, 45.9% agreed it may cause another COVID-19 wave in Saudi Arabia and 46.1% indicated the possibility of another lockdown. Overall, the HCWs worry level of the Omicron variant correlated significantly and strongly with their perception of the effectiveness of vaccination and preventive measures. Male HCWs had a significant agreement with mandatory vaccination of all eligible adult populations while HCWs who are unwilling to receive the vaccine had a strong disagreement with mandatory vaccination. Conclusions: The current study was conducted in the first week of Omicron variant discovery in KSA and only two-thirds of HCWs felt that vaccination is the best option to prevent the variant spread, indicating the need to further motivation campaigns for vaccination and booster doses education among HCWs. HCWs had a strong belief in non-pharmacologic interventions that should be encouraged and augmented. It is important to further study and enhance coping strategies for HCWs as we move through the third year of the pandemic with more potential variants, to protect HCWs from fatigue and burnout.
A Pilot Basket Study to Evaluate Multi-Analyte Liquid Biopsies for Personalized Treatments in Advanced Refractory Cancers

Prior attempts at personalizing anticancer treatments based on univariate tumor profiling (single gene variant) for selection of monotherapy with targeted agents (single drug) have generally yielded poor response rates. We report findings from the LIQUID IMPACT pilot trial where Multi-analyte Liquid Biopsy (MLB) profiling of circulating tumor analytes in peripheral blood was used to inform selection of personalized combination regimens in advanced refractory cancers. Among the 43 patients evaluable as per study protocol, 34 had targetable pathway activations. Partial Response (PR) was observed in 14 (41.1%) of the 34 patients with signaling pathway activation, including 5 (50%) of 10 cases with mTOR activation, 8 (44.4%) of 18 cases with activation of angiogenesis and 4 (50.0%) of 8 cases with EGFR / ERBB2 activation. PR was not reported among the 9 cases with no detectable pathway activation. Toxicities were manageable and there were no treatment related deaths. The study findings suggest that MLB may be able to inform safe and efficacious combination regimens in patients with advanced refractory cancers.
IgE multiple myeloma: detection and follow-up

Abstract Objectives We report a new case of immunoglobulin E multiple myeloma (IgE), a very rare isotype that accounts for <0.1% of cases of this monoclonal gammopathy. To ensure the adequate detection, quantification and identification of the monoclonal component, it is crucial that protein assays are performed. We provide some clues related to clinical laboratory results, which will facilitate an adequate management of the disease. Case presentation A 45-year-old patient with a five-week history of pain at the level of the elbow, who was diagnosed with IgE-Kappa multiple myeloma based on laboratory, radiological, and bone marrow findings. The patient received induction chemotherapy prior to hematopoietic stem-cell transplantation and is currently on follow-up. Conclusions Protein assays performed in the clinical laboratory, including protein electrophoresis and immunofixation, allowed for the detection of an IgE-Kappa monoclonal component prior to the appearance of the typical CRAB symptoms (hypercalcemia, renal involvement, anemia, and bone pain) of multiple myeloma (MM). The detection of IgE-Kappa facilitated early diagnosis and management.
Political Messaging Over Time: A Comparison of US Presidential Candidate Facebook Posts and Tweets in 2016 and 2020

Political campaigns have a temporal nature, which means that the strategic environment shapes the nature of candidate communication, especially the stages of campaigning—from surfacing to the general election. As social media platforms have matured and political campaigns have normalized their use of those platforms in this decade, this study examines the 2016 and 2020 US presidential campaign communication on Facebook and Twitter using data from the Illuminating project at Syracuse University. Our objective is to explore how the stages of the campaign cycle shape political communication. We also explore social media platforms as additional factors. Moreover, given the distinct and anti-normative communication style of Donald Trump, we examine whether his communication is an outlier relative to his competition in the primaries and the general election, and while a challenger in 2016 and an incumbent in 2020. Our results suggest that campaign messaging changes over the stages of the campaign, with candidates more likely to advocate for themselves during the crowded primaries, and then engage in high volumes of calls to action in the general election. The 2016 posts were substantially more attack-focused than in 2020. There is some evidence to suggest that the global pandemic affected the ways in which campaigns used their social media accounts. Of note, campaigns seem to heavily rely on Facebook for all types of strategic communication, even as the academic community primarily analyzes Twitter. Finally, Trump’s sum-total of his discourse is less negative than Clinton’s in 2016 and more advocacy-focused, overall.
ALResNet: Attention-Driven Lightweight Residual Network for Fast and Accurate Image Recognition

In recent years, the optimization of network architecture plays an increasingly important role in the performance improvement of neural networks. We introduce an interactive dual-branch attention mechanism and three different lightweight-oriented strategies to build an accurate and compact residual network model in this work. The channel attention and spatial attention are fused to construct a novel bottleneck to enhance the feature representation ability for accurate performance. Asymmetric convolutions with spatial factorization, channel splitting, depthwise separable convolution with width multiplier adjustment are further combined to compress the parameter size of the attention-driven model for a lightweight and compact residual network named ALResNet. The experimental results of 92.1% top-1 testing accuracy at the inference speed of 14.90 fps on Animals-10 and 89.4% top-1 testing accuracy at the inference speed of 16.21 fps on CIFAR-10, as well as 4.77M parameters and 736.82 MFLOPs, demonstrate that the proposed ALResNet achieves a decent tradeoff between accuracy and computing efficiency for fast inference on resource-limited mobile devices for vision-based tasks.
Addiction to Social Networking Sites and User Responses

Prior studies have primarily used "variable-centered" perspectives to identify factors underlying user responses to social networking site (SNS) addiction, their predictors and outcomes. This paper extends this perspective by taking a person-centered approach to examine (1) the prototypical subpopulations (profiles) of users' extent of SNS addiction and responses to it, (2) how affiliations with these profiles can explain user behaviors toward SNS use, and (3) how personality traits can predict affiliations with these profiles. To this end, we propose a typological theory of SNS addiction and user responses to it via two empirical, personcentered studies. Study 1 draws on survey data from 188 SNS users to develop a typology of users based on the extent of their SNS addiction and their responses to it. It further examines the relations between affiliation with these profiles and users' SNS discontinuance intention, as a typical behavioral response to SNS addiction. Study 2 uses survey data from 284 SNS users to validate the user typology developed in Study 1 and investigate its relations to users' Big Five personality traits. Our findings shed light on a typology of five prototypical profiles of SNS users-cautious, regular, consonant, dissonant, and hooked-who differ in their extent of SNS addiction and their cognitive, emotional, and behavioral responses to it. Our findings also demonstrate how Big Five personality traits can predict user affiliations with these prototypical profiles.
Machine Learning Approaches to Investigate the Relationship between Genetic Factors and Autism Spectrum Disorder

Autism Spectrum Disorder (ASD) is a heterogeneous complex neu-rodevelopment disorder that affects 1 to 2 percent of global population. Over the past years, a sizeable body of research has expanded the knowledge about the pathogenesis of ASD, and identified a list of genotypes that are strongly related to the ASD. However, the complexity of genotype system forces researchers to explore novel approaches. Among all the approaches to understand the roles and interactions of these gene variants, using machine learning (ML) and big data analysis to discover the potential ASD related genotypes is a promising one, while only a few researchers have explored this field. We conducted a data analysis research based on the genetic data of ASD patients, provided a statistical approach to explore the genetics of ASD through genotypes, and identified an important weighted list of ASD related genotypes for further biological research.
Breeding biology and nest survival of the Rusty-backed Antwren (Formicivora rufa)

ABSTRACT Breeding biology data are crucial for avian life history theory, but this information is unavailable for nearly half of the current living tropical bird species. Predation is the main driver of nest survival among tropical birds, and spatial and temporal factors may affect nest predation risk and survival. In this study, we describe the breeding biology of the Rusty-backed Antwren (Formicivora rufa), a bird that inhabits a coastal sandy plain in southeastern Brazil, and examine the effects of date and microhabitat features on nest survival. We found 47 nests over 2 breeding seasons. The nesting season lasted 7–8 months. The mean (± SD) nest-building time was 7.3 ± 1.1 d, the mean incubation period was 16 ± 1.9 d, and nestlings remained in the nest for 10 ± 0.8 d for a full nesting cycle that lasted for ∼26 d. Clutches invariably had 2 eggs and egg-laying occurred over 2 consecutive days. Males and females were both observed building nests, incubating eggs, and feeding nestlings and fledglings. We also report a nestling with a depigmented body, which may represent albinism. Most nests were depredated (68.1%, n = 32). Nest survival was constant throughout the breeding seasons and did not vary with microhabitat features (nest height above the ground, and vertical and horizontal distances between nest and shrub edges). The nesting biology of the Rusty-backed Antwren fits the general pattern typical of antbirds, and micro-spatial or temporal features cannot predict nest survival in our study population.
Nest description, nest survival, and habitat use of three resident hummingbird species in western Mexico

ABSTRACT Nesting is a particularly sensitive period during which birds are highly vulnerable to predation, parasitism, and other natural events resulting in high mortality rates. Some factors can increase nesting success, such as habitat selection. In general, only female hummingbirds build nests, incubate eggs, and provide nestling care until chicks can feed independently. The purpose of our study was to describe nests (shape, size, and construction materials), nest survival, and habitat use of 3 resident hummingbirds in western Mexico: Cinnamon Hummingbird (Amazilia rutila), Golden-crowned Emerald (Cynanthus auriceps; a Mexican endemic), and Broad-billed Hummingbird (C. latirostris). In all 3 species, the nest is an open cup built with plant material and bound together with spider web. All 3 species used the same materials (silk cotton, wood, and grass) for nest construction. However, Cinnamon Hummingbird was the only one that used lichens at its outer surface, whereas Broad-billed Hummingbird used only seeds. We did not find interspecific differences among the materials used and their quantities. A low nest survival (26%) can be explained by the high rate of predation but also by the occurrence of natural events such as hurricanes. All 3 species showed preference for nesting in semi-deciduous forests but chose different nest placement sites that differed in (1) nest height, (2) the height of trees or shrubs where nests were built, and (3) the diameter of the supporting branch within a shrub or tree. Other factors, such as distance to the nearest stream, and distance to nesting-branch tip or trunk, did not differ among species.
Inter- and intracontinental migration by the Eastern Kingbird (Tyrannus tyrannus)

ABSTRACT We recovered 12 archival geolocators deployed on Eastern Kingbirds (Tyrannus tyrannus) breeding in New York (NY; n = 3, 2 with 2 years of data), Nebraska (NE; n = 6, 1 with 2 years of data), and Oregon (OR; n = 3) to describe migratory routes, timing and rates of migration, nonbreeding season distributions, and migratory connectedness. NY fall migrants migrated along the Atlantic coast to Florida, flew either nonstop across the Gulf of Mexico (GoM; 2 of 3 birds) or stopped once along the way (Cuba and Cayman Islands in different years) to land in Yucatan/Central America. Fall birds from NE and OR arrived at the GoM in the region of the border between Texas and Louisiana, and most likely took a land route to Central America. In spring, all NY birds flew nonstop across the GoM, and once in North America, took a more inland route than in fall. Trans-GoM flights were more common among NE and OR birds in spring than fall. Birds migrated faster in spring than fall, and in both seasons, late departure was associated with more rapid migration. Migratory connectivity was low, and all birds from OR, and one bird from NE and NY each, occupied a single region in northwestern Amazonia (southern Colombia, northern Peru, and eastern Ecuador) while in South America. Most kingbirds from NE and NY were intratropical migrants, occupying 2 regions for periods of ≥30 d. The latter birds migrated farther south to western Brazil and northern Bolivia, but then moved north to later use the same area in northwestern Amazonia where other birds remained throughout the overwinter period. Northwestern Amazonia thus appears to be a critical area for all Eastern Kingbirds during the nonbreeding season, possibly because a prolonged wet season supports abundant fruit resources.
Linking Corporate Social Responsibility to Workplace Deviant Behaviors: Mediating Role of Job Satisfaction

The purpose of this article is to present a mechanism through which the deviant work behaviors of employees can be dealt-with positively through corporate good deeds in the form of fulfilling social responsibilities. Based on the spirit of social identity theory and social exchange theory, the study explores the relationships of various deviant behaviors with corporate social responsibility (CSR) through the mediation mechanism of job satisfaction. Data were collected from 385 employees of 40 large manufacturing organizations involved in CSR activities operating in Pakistan. A self-report survey was conducted using a close-ended questionnaire. Data analysis was performed using SEM through Mplus 7. The results reveal that both internal and external CSR contribute to the reduced level of turnover intention, counterproductive work behaviors, and prohibitive voice behaviors. Job satisfaction fully mediates the relationship for internal CSR while partially mediates for external CSR. The study encourages the practitioners to avail approaches that convey the feelings of care, concern, and safety, representing internal CSR practices through diverse HR interventions, organizational support, and justice. They should also keep up the socially responsible behaviors aiming toward the larger community.
Calcium-Prolactin Secretion Coupling in Rat Pituitary Lactotrophs Is Controlled by PI4-Kinase Alpha

The role of calcium, but not of other intracellular signaling molecules, in the release of pituitary hormones by exocytosis is well established. Here, we analyzed the contribution of phosphatidylinositol kinases (PIKs) to calcium-driven prolactin (PRL) release in pituitary lactotrophs: PI4Ks - which control PI4P production, PIP5Ks - which synthesize PI(4, 5)P2 by phosphorylating the D-5 position of the inositol ring of PI4P, and PI3KCs – which phosphorylate PI(4, 5)P2 to generate PI(3, 4, 5)P3. We used common and PIK-specific inhibitors to evaluate the strength of calcium-secretion coupling in rat lactotrophs. Gene expression was analyzed by single-cell RNA sequencing and qRT-PCR analysis; intracellular and released hormones were assessed by radioimmunoassay and ELISA; and single-cell calcium signaling was recorded by Fura 2 imaging. Single-cell RNA sequencing revealed the expression of Pi4ka, Pi4kb, Pi4k2a, Pi4k2b, Pip5k1a, Pip5k1c, and Pik3ca, as well as Pikfyve and Pip4k2c, in lactotrophs. Wortmannin, a PI3K and PI4K inhibitor, but not LY294002, a PI3K inhibitor, blocked spontaneous action potential driven PRL release with a half-time of ~20 min when applied in 10 µM concentration, leading to accumulation of intracellular PRL content. Wortmannin also inhibited increase in PRL release by high potassium, the calcium channel agonist Bay K8644, and calcium mobilizing thyrotropin-releasing hormone without affecting accompanying calcium signaling. GSK-A1, a specific inhibitor of PI4KA, also inhibited calcium-driven PRL secretion without affecting calcium signaling and Prl expression. In contrast, PIK93, a specific inhibitor of PI4KB, and ISA2011B and UNC3230, specific inhibitors of PIP5K1A and PIP5K1C, respectively, did not affect PRL release. These experiments revealed a key role of PI4KA in calcium-secretion coupling in pituitary lactotrophs downstream of voltage-gated and PI(4, 5)P2-dependent calcium signaling.