Miracle-dz/UniFAR-FTUs huggingface dataset:
Detection of molecular gas in a distant submillimetre galaxy at z= 4.76 with Australia Telescope Compact Array: CO(2-1) in an SMG at z = 4.76

We have detected the CO(2–1) transition from the submillimetre galaxy (SMG) LESS J033229.4 − 275619 at z = 4.755 using the new Compact Array Broadband Backend system on the Australian Telescope Compact Array. These data have identiﬁed a massive gas reservoir available for star formation for the ﬁrst time in an SMG at z ∼ 5. We use the luminosity and velocity width (full width at half-maximum, FWHM, of (cid:3) 160 km s − 1 ) of the CO(2–1) line emission to constrain the gas and dynamical mass of M gas (cid:3) 1.6 × 10 10 M (cid:4) and M dyn ( < 2 kpc) (cid:3) 5 × 10 10 (0.25/sin 2 i ) M (cid:4) , respectively, similar to that observed for SMGs at lower redshifts of z ∼ 2–4, although we note that our observed CO FWHM is a factor of ∼ 3 narrower than typically seen in SMGs. Together with the stellar mass we estimate a total baryonic mass of M bary (cid:3) 1 × 10 11 M (cid:4) , consistent with the dynamical mass for this young galaxy within the uncertainties. Dynamical and baryonic mass limits of high-redshift galaxies are useful tests of galaxy formation models: using the known z ∼ 4–5 SMGs as examples of massive baryonic systems, we ﬁnd that their space density is consistent with that predicted by current galaxy formation models. In addition, these observations have helped to conﬁrm that z ∼ 4–5 SMGs possess the baryonic masses and gas consumption time-scales necessary to be the progenitors of the luminous old red galaxies seen at z ∼ 3. Our results provide a preview of the science that ALMA will enable on the formation and evolution of the earliest massive galaxies in the Universe.
Clinical Characteristics of Recurred Patients with Stage I ,II Non-Small Cell Lung Cancer

Background : Five year survival rate of postoperative stage I non-small cell lung cancer(NSCLC) reaches to 66%. In the remaining one third of patients, however, cancer recurs and the overall survival of NSCLC remains dismal. To evaluate clinical and pathologic characteristics of recurred NSCLC, the patterns and factors for postoperative recurrence in patients with staged I and II NSCLC were studied. Method : A retrospective analysis was performed in 234 patients who underwent radical resection for pathologic stage I and II NSCLC. All patients who were followed up for at least one year were included in this study. Results : 1) There were 177 men and 57 women The median age was 63. The median duration of the follow up period was 732 days (range 365~1,695 days). The overall recurrence rate was 26.5%, and the recurrence occurred days after operation. 2) The ages of recurred NSCLC patients were higher ( years) than those of non-recurred patients ( years)(p=0.043). The recurrence rate was higher in stage II (46.9%) than in stage I (18.8%) NSCLC p) than that of non-recurred NSCLC (, p
Antimicrobial susceptibility patterns of ESBL Escherichia coli isolated from community and hospital-acquired urinary tract infections

Context: Increasing resistance of extended-spectrum β-lactamases (ESBL) producing bacteria is an important challenge for clinicians. Aims: Monitor the antibiotic susceptibility pattern of community and hospital acquired urinary tract infections (UTIs) caused by ESBL Escherichia coli. Settings and Design: This is a retrospective observational study that was conducted at a tertiary hospital in Riyadh. Materials and Methods: Results of urine culture with E. coli and their bacterial antimicrobial susceptibility were collected from patients' records for the years 2011 and 2012. When there was bacterial resistance to three groups of antibiotics, a multi-drug resistant (MDR) pattern was considered. Results: Of 3,967 patients with E. coli UTIs, 1,086 (27.4%) of patients had ESBL E. coli. Mean age of the study population in years was 39.1 (±28.8), 67.5% were females, and 32% were in the paediatric age group. The percentage of hospital-acquired ESBL E. coli was 64.5%, while outpatient-acquired was 35.5%. Overall, 75.1% of ESBL E. coli were resistant to trimethoprim/sulfamethoxazole, (69.8%) to ciprofloxacin and (40%) to gentamicin. However, high sensitivity to imipenem and meropenem was reported (99.8% each). Out of all the identified ESBL E. coli, MDR strains were identified in 137 (46%), and 161 (54%) isolates during the years 2011 and 2012, respectively. Conclusion: This study highlights the source and current antimicrobial susceptibility pattern of ESBL E. coli. Since bacterial multidrug resistance is an increasingly existing problem, periodical monitoring of antimicrobial susceptibility, rotating the use of effective antimicrobial drugs, and research for finding novel drugs and their rational use should be considered.
The evolving use of administrative health data for quantifying burden of illness

The aim of this thesis is to demonstrate how the use of administrative health data (AHD) has evolved over time to be a valuable resource for quantifying disease burden. AHD are defined as data routinely collected for the purposes of payment, monitoring, priority setting, and evaluation of the provision of health services. While the primary purpose of AHD is not research, and researchers typically do not have a direct role in their collection, they represent a rich source of data for secondary analyses. The thesis presents and critiques 12 peer-reviewed publications to demonstrate how the use of AHD has evolved for better understanding the burden of disease. Each publication shows a natural evolution in thinking, and sophistication of methods that help to illustrate how secondary data can be used to augment primary data collection methods. The development of evidence using different methods, particularly when there are consistent results, works to strengthen our understanding of any given health issue. The thesis defines AHD, as well as its strengths and limitations, and how these data can be considered ‘big data’. Next, historical developments on secondary use and AHD are provided starting with the work of John Graunt, and ending with the present author. The value of AHD is explored critically through the following themes: role of mortality and hospitalisation data; development of algorithms for improving the accuracy of AHD for determining the presence of disease (case definition algorithms); strength and value of longitudinal designs; identification of rare health events; assessing the burden of co-morbidities; assessing health outcomes; and finally how AHD can support policy development. Future directions for research are highlighted, as well as how AHD can be used to inform policy, resource allocation, and practice.
Chapter 8. Hyperosmolar therapy

Hypertonic saline should be considered for the treatment of severe pediatric TBI associated with intracranial hypertension. Effective doses as a continuous infusion of 3% saline range between 0.1 and 1.0 mL/kg of body weight per hour administered on a sliding scale. The minimum dose needed to maintain intracranial pressure (ICP) 20 mm Hg should be used. Serum osmolarity should be maintained 360 mOsm/L. *Although mannitol is commonly used in the management of raised ICP in pediatric TBI, no studies meeting inclusion criteria were identified for use as evidence for this topic.
64 FOUR WEEKS OF INDINAVIR DOES NOT ALTER ADIPOGENIC TRANSCRIPTION FACTORS IN HEALTHY HIV-NEGATIVE SUBJECTS.

Introduction and Purpose HIV-infected patients on antiretroviral therapy have been reported to develop a lipodystrophy syndrome. Both HIV-1 protease inhibitors, as well as nucleoside analogue reverse transcriptase inhibitors, have been implicated. However, it is unclear if this is a direct drug effect or a result of an interaction between the drug and the underlying HIV infection. In order to dissect out the direct role of drug alone in this process, we studied the in vivo effect of a single protease inhibitor, indinavir, on the key adipogenic transcription factors C/EBPa, SREBP1c, and PPARg. Methods We obtained abdominal subcutaneous adipose tissue samples from seven HIV-negative subjects at baseline and after 4 weeks of daily oral indinavir at 800 mg three times a day. Adipocytes were obtained by collagenase digestion, and total RNA was isolated by standard methods. Expression of C/EBPa, SREBP1c, and PPARg mRNA was quantitated by real time reverse transcription normalized to expression of b-actin using the delta Ct method. Results The subjects had a mean age of 36 ± 3 years, with a mean BMI of 29.5 ± 9 kg/m2. There was no change in BMI or waist-to-hip ratio after 4 weeks of indinavir. Indinavir treatment had no effect on expression of C/EBPa (304.0 ± 32.3 vs 359. 2 ± 43.4), SREBP1c (82.0 ± 14.0 vs 104.9 ± 34.0), or PPARg (350.7 ± 54.0 vs 351.0 ± 48.8 relative units). Conclusions Four weeks of the protease inhibitor indinavir does not alter adipogenic transcription factors in healthy HIV-negative subjects. Our findings indicate that indinavir does not appear to have a direct role in the development of lipodystrophy, suggesting that the lipodystrophy is likely either due to an interaction between drug and disease or attributable to antiretroviral agents other than indinavir.
Early-Phase Outcomes from a Randomized Trial of Intensive Judicial Supervision in an Australian Drug Court

This study examined the short-term outcomes from a randomized trial of intensive judicial supervision (IJS) in an Australian drug court. One hundred thirty-six participants were randomly allocated into IJS or supervision-as-usual (SAU) conditions. The IJS group reported back to the judge twice weekly during Phase 1, and the SAU group reported back weekly. IJS participants had lower odds of returning positive urinalysis tests and accumulated fewer sanctions (accrued days in custody) than those in the SAU group. There was no significant difference in the rate at which sanctions were served in prison, time spent on the program, progression to later program phases, or likelihood of graduating from the program, although there was low statistical power to detect differences in these latter outcomes. Intensively supervising drug court participants clearly reduces early-phase substance use and sanction accrual rates. The impact of IJS on longer-term outcomes remains to be seen.
Regularity criteria for the 3D MHD equations via partial derivatives. II

In this paper, we establish two regularity criteria for the 3D MHD equations in terms of partial derivatives of the velocity field or the pressure. It is proved that if $\partial_3 u \in L^\beta(0,T; L^\alpha(\mathbb{R}^3)),~\mbox{with}~ \frac{2}{\beta}+\frac{3}{\alpha}\leq\frac{3(\alpha+2)}{4\alpha},~\alpha>2$, or $\nabla_h P \in L^\beta(0,T; L^{\alpha}(\mathbb{R}^3)),~\mbox{with}~\frac{2}{\beta}+\frac{3}{\alpha}< 3,~\alpha>\frac{9}{7},~\beta\geq 1$, then the weak solution $(u,b)$ is regular on $[0, T]$.
Factors Influence the Utilization of Community Participation (POSBINDU)

Posbindu is a form of public participation to conduct early detection and monitoring of risk factors for non-communicable diseases (NCD), and where it was carried out in as an integrated-manner, routine and periodic event. Posbindu itself aimed to promote the community participation in prevention and early detection of risk factors for non-communicable disease (NCD). Non-communicable diseases is the biggest killer in the world,causing approximately 60% of global deaths. More than 9 millions of all deaths related to NCD occurred under the age 60 years old, and 90% premature deaths incidence occurs in countries where significant number of population were low income-population. In Indonesia, death related to NCD are growing in an alarming rate, from approximately 41% at the year 1995, striking 59,5% at year 2007. According to Basic Health Survey of 2007, NCD related deaths ranked number 6 in a top ten Death list.The growing rate of NCD prevalence are to become a serious threat upon national Development, death risk from disease related condition will negatively impact human resources nationwide, which the effect will surely not limited to health aspect only but expanded to economic aspect.Meanwhile, Posbindu program had not reach its popularity as it should have been. In some region, posbindu visits by locals has decreased. At the study area, existing data showed that, only as much as 10% of the local population was using Posbindu service. In many regions, Posbindu were deemed to merge with geriatric social health care, as the major user was the geriatric population.
Sub-Chronic Treatment of Sildernafil Citrate (Viagra) on some Enzymatic and NonenzymaticAntioxidants in Testes and Brain of Male Rats

Sub-Chronic Treatment of Sildernafil Citrate (Viagra) on some Enzymatic and Nonenzymatic Antioxidants in Testes and Brain of Male Rats Sildenafil citrate, a specific phosphodiesterase-5 (PDE-5) inhibitor drug currently used for the treatment of erectile dysfunction in men. The present study investigates the effects of Sildenafil citrate on antioxidant defense systems of testes and brain tissues of male rats by measuring the GSH, SOD, and CAT activity. Lipid peroxidation was also estimated by measuring the MDA levels, a Thiobarbituric Acid Reactive Substrate (TBARS) as biomarker of oxidative stress. Sildenafil citrate was orally administered at the different dose levels of 20 mg/kg body weight per 30 days in four divided doses of 50, 100, 150 and 200 mg/kg body weight while control rats were given distilled water.
Acoustic radiation force impulse (ARFI) elastography of testicular disorders in dogs: preliminary results

The aim of this study was to describe the use of acoustic radiation force impulse (ARFI) elastography in the evaluation of testicular disorders in dogs. Eighteen dogs with testicular disorders (thirty-six testicles) were assessed. Echotexture, size, contours and margins of testes were analysed by ultrasonography. Deformities and tissue stiffness (greyscale and homogenous or heterogeneous) were evaluated by qualitative elastography and shear velocity was determined quantitatively. Subsequent to orchiectomy, testicular samples were collected for histopathology analysis and thirty-six disorders were identified. Qualitative elastography revealed that normal healthy testicular tissues were homogenous and not pliable while the affected testicles had alterations in tissue stiffness and homogeneity. The values obtained for quantitative elastography of the testicular tissues were: normal/healthy - 1.30±0.12 m/s; degenerated - 0.97±0.08 m/s; atrophied - 2.00±0.35 m/s; hypoplastic - 0.82±0.2 m/s; cystic - 1.32±0.18 m/s; orchitis - 2.68±0.42 m/s; interstitial cell tumours - 3.32±0.65 m/s; sertolioma - 2.99±0.07 m/s and leydigoma - 2.73±0.37. ARFI elastography of abnormal testes proved to be an applicable and complementary technique in the diagnosis of testicular disease in dogs.
A search for new members of the β Pictoris, Tucana-Horologium and ε Cha moving groups in the RAVE data base: New members of young moving groups

We report on the discovery of new members of nearby young moving groups, exploiting the full power of combining the Radial Velocity Experiment (RAVE) survey with several stellar age diagnostic methods and follow-up high-resolution optical spectroscopy. The results include the identification of one new and five likely members of the β Pictoris moving group, ranging from spectral types F9 to M4 with the majority being M dwarfs, one K7 likely member of the Cha group and two stars in the Tucana–Horologium association. Based on the positive identifications, we foreshadow a great potential of the RAVE data base in progressing towards a full census of young moving groups in the solar neighbourhood.
A Comparison of Spot Urine Protein-Creatinine Ratio vs. 24 hours Urinary Protein Excretion in Women with Pre Eclampsia

Objective: To evaluate diagnostic accuracy of spot urine protein-creatinine ratio for the diagnosis of proteinuria among patients with preeclampsia taking 24 hours urinary protein concentration > 300 mg/24hrs as gold standard. Study Design: This was a cross sectional study. Introduction: Preeclampsia can lead to significant morbidity and mortality. One of the important characteristic of diagnosis of preeclampsia is proteinuria. Gold standard for detection of significant proteinuria among these patients is 24 hours urinary proteins level (>300 milli grams). However, spot urinary protein-creatinine ratio can also detect proteinuria and save patients from botheration for collection of 24 hours urine. Previously, variable sensitivities, specificities and diagnostic accuracy of spot urinary protein-creatinine ratio had been calculated. So, this study was designed to determine diagnostic accuracy of spot urinary protein-creatinine ratio. Methods: 551 patients with preeclampsia were included. All patients had spot urinary protein-creatinine ratio (>0.3 was cutoff for proteinuria). All patients had 24 hours urinary protein test (>300 grams cutoff for proteinuria) as gold standard. Diagnostic accuracy of urinary protein-creatinine ratio was detected by determining sensitivity, specificity and accuracy. Results: Sensitivity, specificity, and accuracy of spot urinary protein-creatinine ratio were 95.8%, 94.2% and 91.6%, respectively. Conclusions: Due to its high sensitivity, specificity and diagnostic accuracy, urinary protein-creatinine ratio is a reliable test for diagnosing proteinuria among patients with preeclampsia.
Prevalence Rates of Risk Factors of Metabolic Syndrome, and Its Related with Obesity Indices Among the Health Checkup Examinees

The aim of this study was to estimate the prevalence of the metabolic syndrome risk factors for adults in the general population, understand the relationship of each factor with the obesity indicators, and examine the relevance and validity for predicting the metabolic syndrome in obese indicators. The study subjects were 1,051 adults aged 20 years and over, who underwent a health package check-up at the Korea Association of Health Promotion, D-branch from Feb. to Nov. 2014. As a result, the prevalence rates of metabolic syndrome of the study subjects were 21.5%, and the prevalence rates of the metabolic risk factors were as follows: 31.8% of men and 41.6% of women for abdominal obesity; 35.6% of men and 17.3% of women for TG; 17.6% of men and 34.2% of women for HDL-C; 53.5% of men and 35.9% of women for blood pressure; and 14.9% of men and 6.8% of women for FBS. The prevalence rates of metabolic syndrome were significantly higher in the older age group, in the group with the higher BMI, and in the group of higher level of drinking frequency. In the predictive indicators of obesity on metabolic syndrome risk factors, the waist / height ratio was higher than other indicators. Conclusively, WHtR appeared to be a useful indicator to show abdominal obesity and is better in selecting metabolic syndrome patients compared to other obesity indicators.
ON CONVEX FUNCTIONS, E-CONVEX FUNCTIONS AND THEIR GENERALIZATIONS: APPLICATIONS TO NON-LINEAR OPTIMIZATION PROBLEMS

An important class of generalized convex sets and convex functions, called Econvex sets and E-convex functions, have been introduced and studied by Youness and other researchers. This class is proved to be useful in pure and applied mathematical fields. In this paper, some new characterizations of convex function, E-convex function, and their generalizations are discussed in terms of some level sets and different forms of epigraphs which are related to these functions. As an application of generalized convex functions in optimization problems, the optimality conditions of non-linear optimization problem using E-convex function (respectively, strictly E-convex function) and its generalizations such as E-quasiconvex function (respectively, strictly E-quasiconvex) function, and strictly quasi semi E-convex function are discussed. AMS Subject Classification: 46N10, 47N10, 90C48, 90C90, 49K27
CALCULATION OF MODE PARAMETERS OF WALL BEAD DEPOSITION IN DOWNHAND MULTI-PASS GAS-SHIELDED WELDING

Application of narrowed grooves is an effective method to increase welding process efficiency at simultaneous reduction of financial and energy expenses. One of the main difficulties in implementation of multi-pass welding technology 10 mm thick rolled metal structures using automated and robotized units is a high possibility of defect formation such as lack of penetration, in particular, in layer of the first pass (wall bead). Control of welding parameters determining heat input is one of the methods of penetration regulation. Dependencies between welding parameters in problem areas of the grooves and penetration depth were determined experimentally. On their basis the equations for determination of parameters of bead deposition at given coefficient of areas were obtained. These results became a part of algorithm development to control welding mode parameters in automated and robotized units. 12 Ref. , 1 Table, 6 Figures.
WEED INTERFERENCE PERIODS IN PRE-SPROUTED SUGARCANE SEEDLINGS

The aim of this research was to determine weed interference periods in sugarcane cultivated under the system of pre-sprouted seedlings, taking into account the impact on the final plant stand, and bud yield and stalk yield. In the field, this study used a randomized block design with 14 treatments and four replications. The treatments consisted of periods of control and weed coexistence with the sugarcane crop (cultivar IACSP95-5000): 30, 60, 90, 120, 150, 180, 210 and 240 days after planting. A phytosociological survey was carried out in the experimental area, and the species Merremia aegyptia, Urochloa decumbens and Nicandra physaloides were found to be predominant. At the end of 240 days, regression analysis was performed according to Boltzmann’s sigmoidal model and considering loss tolerance of 5% in the evaluated variables. For final plant stand, the period prior to interference was 31 days and the total period of interference prevention was 187 days. For bud yield, the period prior to interference was 23 days and the total period of interference prevention was 178 days. For stalk yield, the period prior to interference was 19 days and the total period of interference prevention was 195 days. Weed interference was detrimental to all evaluated variables, with losses of up to 100% of the sugarcane plants after 120 days of weed coexistence.
CIA_A_200269 1167..1175

1Department of Neurology, Haueundae Paik Hospital, Inje University, Busan, South Korea; 2Department of Neurology, Pusan National University Hospital, Pusan National University School of Medicine and Medical Research Institute, Busan, South Korea; 3Department of Neurology, Ewha Womans University Mokdong Hospital, Ewha Womans University School of Medicine, Seoul, South Korea; 4Department of Neurology, Bobath Memorial Hospital, Seongnam, South Korea; 5Department of Neurology, Inha University School of Medicine, Incheon, South Korea; 6Department of Nuclear Medicine, College of Medicine, Dong-A University, Busan, South Korea; 7Department of Neurology, Cognitive Disorders and Dementia Center, Dong-A University College of Medicine and Institute of Convergence Bio-Health, Busan, South Korea Purpose: We assessed the effect of home-based cognitive intervention (HCI) on cognitive
Turnover Intention Among Probation Officers and Direct Care Staff: A Statewide Study

UP UNTIL NOW there has been no readily available, cost-effective mechanism to fully and empirically analyze actual, voluntary turnover among Texas probation personnel. The Texas State Auditor’s Office (2007) reported a 10.8 percent statewide voluntary turnover rate (excluding involuntary separations and retirements) among all state agencies, except institutions of higher education, during fiscal year 2007. However, that report did not provide any information about the voluntary turnover rate of Texas adult probation personnel. Despite no systematically documented statewide turnover rate for Texas probation, there is much evidence that high levels of employee turnover, and its attendant causes, are critical issues faced by probation executives.