Miracle-dz/UniFAR-FTUs huggingface dataset:
Effective field theory out of equilibrium: Brownian quantum fields

The emergence of an effective field theory out of equilibrium is studied in the case in which a light field—the system—interacts with very heavy fields in a finite temperature bath. We obtain the reduced density matrix for the light field, its time evolution is determined by an effective action that includes the influence action from correlations of the heavy degrees of freedom. The non-equilibrium effective field theory yields a Langevin equation of motion for the light field in terms of dissipative and noise kernels that obey a generalized fluctuation dissipation relation. These are completely determined by the spectral density of the bath which is analyzed in detail for several cases. At T = 0 we elucidate the effect of thresholds in the renormalization aspects and the asymptotic emergence of a local effective field theory with unitary time evolution. At T ≠ 0 ? > new ‘anomalous’ thresholds arise, in particular the decay of the environmental heavy fields into the light field leads to dissipative dynamics of the light field. Even when the heavy bath particles are thermally suppressed this dissipative contribution leads to the thermalization of the light field which is confirmed by a quantum kinetics analysis. We obtain the quantum master equation and show explicitly that its solution in the field basis is precisely the influence action that determines the effective non-equilibrium field theory. The Lindblad form of the quantum master equation features time dependent dissipative coefficients. Their time dependence is crucial to extract renormalization effects at asymptotically long time. The dynamics from the quantum master equation is in complete agreement with that of the effective action, Langevin dynamics and quantum kinetics, thus providing a unified framework to effective field theory out of equilibrium.
The alignment of satellite galaxies and cosmic filaments: observations and simulations

The accretion of satellites onto central galaxies along vast cosmic filaments is an apparent outcome of the anisotropic collapse of structure in our Universe. Numerical work (based on gravitational dynamics of N-body simulations) indicates that satellites are beamed towards hosts along preferred directions imprinted by the velocity shear field. Here we use the Sloan Digital Sky Survey to observationally test this claim. We construct 3D filaments and sheets and examine the relative position of satellite galaxies. A statistically significant alignment between satellite galaxy position and filament axis in observations is confirmed. We find a qualitatively compatible alignments by examining satellites and filaments similarly identified in the Millennium simulation, semi-analytical galaxy catalogue. We also examine the dependence of the alignment strength on galaxy properties such as colour, magnitude and (relative) satellite magnitude, finding that the alignment is strongest for the reddest and brightest central and satellite galaxies. Our results confirm the theoretical picture and the role of the cosmic web in satellite accretion. Furthermore our results suggest that filaments identified on larger scales can be reflected in the positions of satellite galaxies that are quite close to their hosts.
PARSEC-SCALE DUST EMISSION FROM THE POLAR REGION IN THE TYPE 2 NUCLEUS OF NGC 424

Advancements in infrared (IR) interferometry open up the possibility to spatially resolve active galactic nuclei (AGNs) on the parsec-scale level and study the circumnuclear dust distribution, commonly referred to as the “dust torus,” that is held responsible for the type 1/type 2 dichotomy of AGNs. We used the mid-IR beam combiner MIDI together with the 8 m telescopes at the Very Large Telescope Interferometer to observe the nucleus of the Seyfert 2 galaxy NGC 424, achieving an almost complete coverage of the uv-plane accessible by the available telescope configurations. We detect extended mid-IR emission with a relatively baseline- and model-independent mid-IR half-light radius of (2.0 ± 0.2) pc × (1.5 ± 0.3) pc (averaged over the 8–13 μm wavelength range). The extended mid-IR source shows an increasing size with wavelength. These properties are in agreement with the idea of dust heated in thermal equilibrium with the AGN. The orientation of the major axis in position angle ∼ − 27° is closely aligned with the system axis as set by optical polarization observations. Torus models typically favor extension along the mid-plane at mid-IR wavelengths instead. Therefore, we conclude that the majority of the parsec-scale mid-IR emission (≳60%) in this type 2 AGN originates from optically thin dust in the polar region of the AGN, a scenario consistent with the near- to far-IR spectral energy distribution. We suggest that a radiatively driven dusty wind, possibly launched in a puffed-up region of the inner hot part of the torus, is responsible for the polar dust. In this picture, the torus dominates the near-IR emission up to about 5 μm, while the polar dust is the main contributor to the mid-IR flux. Our results of NGC 424 are consistent with recent observations of the AGN in the Circinus galaxy and resemble large-scale characteristics of other objects. If our results reflect a general property of the AGN population, the current paradigm for interpreting and modeling the IR emission of AGNs has to be revised.
Comparing Soil ErosionRates on Terraced and Sloping Cultivated Land in Palestine Using FRN

Department of Chemistry, Arab American University, Jenin, State of Palestine Centre National de L’Energie des Sciences et des Technique Nucleaires (CNESTEN), Division of Water, Soil and Climate, Rabat, Morocco Soil and Water Management and Crop Nutrition Laboratory, e International Atomic Energy Agency (IAEA), Seibersdorf, Vienna, Austria Soil andWater Management & Crop Nutrition Section, Joint FAO/IAEA Division of Nuclear Techniques, Food and Agriculture, International Atomic Energy Agency, Vienna, Austria Department of Chemistry, An-Najah National University, Nablus, State of Palestine Radiation Protection & Detection Unit, Ministry of Health Qadoora Street Ramallah, Ramallah, State of Palestine
Classroom Research: Assessment of Student Understanding of Sampling Distributions of Means and the Central Limit Theorem in Post-Calculus Probability and Statistics Classes

We applied a classroom research model to investigate student understanding of sampling distributions of sample means and the Central Limit Theorem in post-calculus introductory probability and statistics courses. Using a quantitative assessment tool developed by previous researchers and a qualitative assessment tool developed by the authors, we embarked on data exploration of our students' responses on these assessments. We observed various trends regarding their understanding of the concepts including results that were consistent with research completed previously (by other authors) for algebra-based introductory level statistics students. We also used the information obtained from our data exploration and our experiences in the classroom to examine and conjecture about possible reasons for our results. Supplemental data for this article can be accessed on the publisher's website.
Type 1 low z AGN. I. Emission properties

We analyse the emission properties of a new sample of 3579 type 1 AGN, selected from Sloan Digital Sky Survey (SDSS) Data Release 7 based on the detection of broad Hα emission. The sample extends over a broad Hα luminosity LbHα of and a broad Hα full width at half-maximum (FWHM) of , which covers the range of black hole mass 106 < MBH/M⊙ < 109.5 and luminosity in Eddington units 10−3 < L/LEdd < 1. We combine ROSAT, GALEX and 2MASS observations to form the spectral energy distribution (SED) from 2.2 m to 2 keV. We find the following. (1) The distribution of the Hα FWHM values is independent of luminosity. (2) The observed mean optical–ultraviolet (optical–UV) SED is well matched by a fixed-shape SED of luminous quasars, which scales linearly with LbHα, and a host galaxy contribution. (3) The host galaxy r-band (fibre) luminosity function follows well the luminosity function of inactive non-emission-line galaxies (NEGs), consistent with a fixed fraction of ∼3 per cent of NEGs hosting an AGN, regardless of the host luminosity. (4) The hosts of lower luminosity AGN have a mean z-band luminosity and u−z colour which are identical to NEGs with the same redshift distribution. With increasing LbHα the AGN hosts become bluer and less luminous than NEGs. The implied increasing star formation rate with LbHα is consistent with the relation for SDSS type 2 AGN of similar bolometric luminosity. (5) The optical–UV SED of the more luminous AGN shows a small dispersion, consistent with dust reddening of a blue SED, as expected for thermal thin accretion disc emission. (6) There is a rather tight relation between and LbHα, which provides a useful probe for unobscured (true) type 2 AGN. (7) The primary parameter that drives the X-ray to UV emission ratio is luminosity, rather than MBH or L/LEdd.
A brief note on epistemic interpretations and the Kochen-Specker theorem

One of the recent no-go theorems on \Psi-epistemic interpretations of quantum proves that there are no 'maximally epistemic' interpretations of quantum theory. The proof utilises similar arrangements to Clifton's quantum contextuality proof and has parallels to Harrigan and Rudolph's quantum deficiency no-go theorem, itself based on the Kochen-Specker quantum contextuality proof. This paper shows how the Kochen-Specker theorem can also be turned into a no 'maximally epistemic' theorem, but of a more limited kind.
K-band integral field spectroscopy and optical spectroscopy of massive young stellar objects in the Small Magellanic Cloud

We present $K$-band integral field spectroscopic observations towards 17 massive young stellar objects (YSOs) in the low metallicity Small Magellanic Cloud (SMC) and two YSO candidates in the compact H ii regions N81 and N88 A (also in the SMC). These sources, originally identified using $Spitzer$ photometry and/or spectroscopy, have been resolved into 29 $K$-band continuum sources. By comparing Br$\gamma$ emission luminosities with those presented for a Galactic sample of massive YSOs, we find tentative evidence for increased accretion rates in the SMC. Around half of our targets exhibit emission line (Br$\gamma$, He i and H$_2$) morphologies which extend significantly beyond the continuum source and we have mapped both the emission morphologies and the radial velocity fields. This analysis also reveals evidence for the existence of ionized low density regions in the centre outflows from massive YSOs. Additionally we present an analysis of optical spectra towards a similar sample of massive YSOs in the SMC, revealing that the optical emission is photo-excited and originates near the outer edges of molecular clouds, and is therefore consistent with a high mean-free path of UV photons in the interstellar medium (ISM) of the SMC. Finally, we discuss the sample of YSOs in an evolutionary context incorporating the results of previous infrared and radio observations, as well as the near-infrared and optical observations presented in this work. Our spectroscopic analysis in both the $K$-band and the optical regimes, combined with previously obtained infrared and radio data, exposes differences between properties of massive YSOs in our own Galaxy and the SMC, including tracers of accretion, discs and YSO--ISM interactions.
CARBON AND OXYGEN ISOTOPIC RATIOS FOR NEARBY MIRAS

Carbon and oxygen isotopic ratios are reported for a sample of 46 Mira and SRa-type variable asymptotic giant branch (AGB) stars. Vibration–rotation first and second-overtone CO lines in 1.5–2.5 μm spectra were measured to derive isotopic ratios for 12C/13C, 16O/17O, and 16O/18O. Comparisons with previous measurements for individual stars and with various samples of evolved stars, as available in the extant literature, are discussed. Models for solar composition AGB stars of different initial masses are used to interpret our results. We find that the majority of M-stars have main sequence masses ≤2 M⊙ and have not experienced sizable third dredge-up (TDU) episodes. The progenitors of the four S-type stars in our sample are slightly more massive. Of the six C-stars in the sample three have clear evidence relating their origin to the occurrence of TDU. Comparisons with O-rich presolar grains from AGB stars that lived before the formation of the solar system reveal variations in the interstellar medium chemical composition. The present generation of low-mass AGB stars, as represented by our sample of long period variables (LPVs), shows a large spread of 16O/17O ratios, similar to that of group 1 presolar grains and in agreement with theoretical expectations for the composition of mass 1.2–2 M⊙ stars after the first dredge-up. In contrast, the 16O/18O ratios of present-day LPVs are definitely smaller than those of group 1 grains. This is most probably a consequence of the the decrease with time of the 16O/18O ratio in the interstellar medium due to the chemical evolution of the Milky Way. One star in our sample has an O composition similar to that of group 2 presolar grains originating in an AGB star undergoing extra-mixing. This may indicate that the extra-mixing process is hampered at high metallicity, or, equivalently, favored at low metallicity. Similarly to O-rich grains, no star in our sample shows evidence of hot bottom burning, which is expected for massive AGB stars.
FGFR mRNA Expression in Cholangiocarcinoma and Its Correlation with FGFR2 Fusion Status and Immune Signatures

Abstract Purpose: Selective FGFR inhibitors are effective against cholangiocarcinomas that harbor gene alterations in FGFR2. Clinical trials suggest that expression of wild-type FGFR mRNA can predict sensitivity to FGFR inhibitors, but this biomarker has not been well characterized in cholangiocarcinoma. This study explores the prevalence of FGFR mRNA overexpression in cholangiocarcinoma, its role in predicting sensitivity to FGFR inhibitors, and its association with immune markers. Experimental Design: Tissue microarrays of intrahepatic (ICC) and extrahepatic cholangiocarcinomas (ECC) resected between 2004 and 2015 were used to evaluate FGFR1–4 mRNA expression levels by RNA in situ hybridization (ISH). Expression levels of FGFR2 mRNA were correlated with FGFR2 fusion status and with patient outcomes. Immune markers expression was assessed by IHC and CSF1 and CSF1 receptor expression were examined by RNA ISH. Results: Among 94 patients with resected cholangiocarcinoma, the majority had ICC (77%). FGFR2 fusions were identified in 23% of ICCs and 5% of ECCs. High levels of FGFR mRNA in FGFR2 fusion–negative ICC/ECC were seen for: FGFR1 (ICC/ECC: 15%/0%), FGFR2 (ICC/ECC: 57%/0%), FGFR3 (ICC/ECC: 53%/18%), and FGFR4 (ICC/ECC: 32%/0%). Overall, 62% of fusion-negative cholangiocarcinomas showed high levels of FGFR mRNA. In patients with advanced FGFR2 fusion–positive ICC, high levels of FGFR2 mRNA did not correlate with clinical benefit. FGFR2 fusion–positive tumors showed a paucity of PD-L1 on tumor cells. Conclusions: FGFR mRNA overexpression occurs frequently in cholangiocarcinoma in the absence of genetic alterations in FGFR. This study identifies a molecular subpopulation in cholangiocarcinoma for which further investigation of FGFR inhibitors is merited outside currently approved indications.
The effect of cigarette modified risk claims and brand on perceived risk, product appeal, and use intentions

Objectives No studies have examined the brand context in which modified risk claims appear on tobacco products. This study examines how marketing products with modified risk claims affects risk perceptions, appeal, and intentions among own-brand, other brand, and novel brand cigarettes. Methods This experiment employed a 3 (claim: risk modification [RM], exposure modification [EM], control) x 3 (brand: own, other, novel) between-subjects design. A convenience sample (N = 1,557, Mage = 40.28, SDage = 19.01, 71.3% female, 80.3% White) of current or former Marlboro, Camel, or Newport users was collected. Participants were assigned to view their own brand, another brand, or a novel brand, with or without a claim, and rated perceived risk after switching to this product, product appeal, and use intentions. Results Participants in the RM or EM conditions had lower risk perceptions (versus control). Claim did not affect appeal. Adult established cigarette users in the EM (but not RM) condition had higher intentions (versus control). Participants rated their own and another brand as more appealing than the novel brand. Interactions between brand and claim were not significant. Conclusions We found modified risk claims decreased risk perceptions but did not impact appeal. Whereas participants showed preference for their own brand in terms of appeal and intentions, brand did not moderate the impact of claims.
CD8+ T cell exhaustion in anti‐tumour immunity: The new insights for cancer immunotherapy

CD8+ T cells play a crucial role in anti‐tumour immunity, but they often undergo exhaustion, which affects the anti‐tumour activity of CD8+ T cells. The effect and mechanism of exhausted CD8+ T cells have become the focus of anti‐tumour immunity research. Recently, a large number of studies have confirmed that long‐term antigen exposure can induce exhaustion. Cytokines previously have identified their effects (such as IL‐2 and IL‐10) may play a dual role in the exhaustion process of CD8+ T cells, suggesting a new mechanism of inducing exhaustion. This review just focuses our current understanding of the biology of exhausted CD8+ T cells, including differentiation pathways, cellular characteristics and signalling pathways involved in inducing exhaustion, and summarizes how these can be applied to tumour immunotherapy.
Assessing the Topics and Motivating Factors Behind Human-Social Chatbot Interactions: Thematic Analysis of User Experiences

Background Although social chatbot usage is expected to increase as language models and artificial intelligence improve, very little is known about the dynamics of human-social chatbot interactions. Specifically, there is a paucity of research examining why human-social chatbot interactions are initiated and the topics that are discussed. Objective We sought to identify the motivating factors behind initiating contact with Replika, a popular social chatbot, and the topics discussed in these interactions. Methods A sample of Replika users completed a survey that included open-ended questions pertaining to the reasons why they initiated contact with Replika and the topics they typically discuss. Thematic analyses were then used to extract themes and subthemes regarding the motivational factors behind Replika use and the types of discussions that take place in conversations with Replika. Results Users initiated contact with Replika out of interest, in search of social support, and to cope with mental and physical health conditions. Users engaged in a wide variety of discussion topics with their Replika, including intellectual topics, life and work, recreation, mental health, connection, Replika, current events, and other people. Conclusions Given the wide range of motivational factors and discussion topics that were reported, our results imply that multifaceted support can be provided by a single social chatbot. While previous research already established that social chatbots can effectively help address mental and physical health issues, these capabilities have been dispersed across several different social chatbots instead of deriving from a single one. Our results also highlight a motivating factor of human-social chatbot usage that has received less attention than other motivating factors: interest. Users most frequently reported using Replika out of interest and sought to explore its capabilities and learn more about artificial intelligence. Thus, while developers and researchers study human-social chatbot interactions with the efficacy of the social chatbot and its targeted user base in mind, it is equally important to consider how its usage can shape public perceptions and support for social chatbots and artificial agents in general.
A LOW FREQUENCY SURVEY OF GIANT PULSES FROM THE CRAB PULSAR

We present a large survey of giant pulses from the Crab Pulsar as observed with the first station of the Long Wavelength Array. Automated methods for detecting giant pulses at low frequencies where scattering becomes prevalent are also explored. More than 1400 pulses were detected across four frequency bands between 20 and 84 MHz over a seven-month period beginning in 2013, with additional followup observations in late 2014 and early 2015. A handful of these pulses were detected simultaneously across all four frequency bands. We examine pulse characteristics, including pulse broadening and power law indices for amplitude distributions. We find that the flux density increases toward shorter wavelengths, consistent with a spectral turnover at 100 MHz. Our observations uniquely span multiple scattering epochs, manifesting as a notable trend in the number of detections per observation. These results are characteristic of the variable interface between the synchrotron nebula and the surrounding interstellar medium.
The realized efficacy of indoor residual spraying campaigns falls quickly below the recommended WHO threshold when coverage, pace of spraying and residual efficacy on different wall types are considered

Indoor residual spraying (IRS) has been and remains an important malaria control intervention in southern Mozambique, South Africa and Eswatini. A better understanding of the effectiveness of IRS campaigns is critical to guide future elimination efforts. We analyze the three IRS campaigns conducted during a malaria elimination demonstration project in southern Mozambique, the “Magude project”, and propose a new method to calculate the efficacy of IRS campaigns adjusting for IRS coverage, pace of house spraying and IRS residual efficacy on different wall types. Anopheles funestus sensu lato (s.l.) and An. gambiae s.l. were susceptible to pirimiphos-methyl and DDT. Anopheles funestus s.l. was resistant to pyrethroids, with 24h post-exposure mortality being lower for An. funestus sensu stricto (s.s.) than for An. parensis (collected indoors). The percentage of structures sprayed was above 90% and percentage of people covered above 86% in all three IRS campaigns. The percentage of households sprayed was above 83% in 2015 and 2016, but not assessed in 2017. Mosquito mortality 24h post-exposure stayed above 80% for 196 days after the 2016 IRS campaign and 222 days after the 2017 campaign and was 1.5 months longer on mud walls than on cement walls. This was extended by up to two months when 120h post-exposure mortality was considered. The district-level realized IRS efficacy was 113 days after the 2016 campaign. While the coverage of IRS campaigns in Magude were high, IRS protection did not remain optimal for the entire high malaria transmissions season. The use of a longer-lasting IRS product could have further supported the interruption of malaria transmission in the district. To better estimate the protection afforded by IRS campaigns, National Malaria Control Programs and partners are encouraged to adjust the calculation of IRS efficacy for IRS coverage, pace of house spraying during the campaign and IRS efficacy on different wall types combined with wall type distribution in the sprayed area.