Miracle-dz/UniFAR-FTUs huggingface dataset:
Preterm Birth in Assisted Reproductive Technology: An Analysis of More Than 20,000 Singleton Newborns

Background Several studies have shown that newborns conceived through the ART procedures were associated with an increased incidence of preterm delivery compared to those conceived spontaneously regardless of the type of ART procedure. The aim of the study was to explore risk factors for preterm birth (PTB) in assisted reproductive technology. Method In this single center retrospective cohort study, a total of 23,111 singleton newborns from January 2010 to December 2018 were included. The primary outcome in this study was preterm birth, defined as live birth before 37 weeks’ gestation. Result In the 23,111 pregnancies, the incidence of PTB was 7.13%. In multivariate logistic regression analysis model, BMI was an independent predictor for PTB (OR = 1.05, 95% CI: 1.03–1.07; P = 0.00 in IVF/ICSI cycles; OR = 1.08, 95% CI: 1.03–1.12; P = 0.00 in IUI cycles). Also, another independent predictor in ART was male newborns (OR = 1.27, 95% CI: 1.14–1.41; P = 0.00 in IVF/ICSI cycles; OR = 1.60, 95% CI: 1.17–2.18; P = 0.00 in IUI cycles). In IVF/ICSI cycles, PTB was significantly higher in patients with advanced age (9.56% in ≥ 38 years old), and in patients with a history of cesarean section (10.39%). In addition, Blastocyst transfer, and frozen thawed transfer were also risk factor for PTB as compared with cleavage transfer, and fresh transfer, respectively. Moreover, in frozen thawed transfer cycles, stimulated protocol (estrogen-progesterone) increased PTB as compared with natural protocol (OR = 1.33, 95% CI: 1.12–1.59; P = 0.00). This situation was similar in IUI cycles as stimulated protocol also increased PTB when compared with natural protocol (OR = 1.72, 95% CI: 1.19–2.48; P = 0.00). Conclusion Body mass index (BMI), delivery with male newborn, as well as stimulated protocols, were independent risk factors for PTB in both IVF/ICSI and IUI treatment cycles. In IVF/ICSI cycles, independent risk factors also included maternal, history of cesarean section, frozen thawed transfer, and blastocyst transfer.
Factors Associated with Health Behaviors in Thyroid Cancer Survivors

In this study, we compared health behaviors, including current smoking, drinking, and physical inactivity, in thyroid cancer survivors and non-cancer controls and investigated the factors associated with unhealthy behaviors among survivors. Baseline data from the Health Examinees study, collected from 2004 to 2013, were used. Thyroid cancer survivors (n = 942), defined as those who had received a clinical diagnosis of thyroid cancer, and 9,420 matched non-cancer controls without past history of any cancer were included in the analysis. The prevalence of smoking, alcohol consumption, and physical inactivity in thyroid cancer survivors were 2.3%, 26.6%, and 52.0%, respectively, with adjusted OR (aOR) and 95% CI between survivors and non-cancer controls of 0.35 (95% CI = 0.08-1.56), 0.46 (95% CI = 0.29-0.74), and 0.65 (95% CI = 0.44-0.96). The prevalence of unhealthy behaviors was higher among male thyroid cancer survivors than female thyroid cancer survivors. In thyroid cancer survivors, those who smoked were more likely to drink (aOR = 4.55 [95% CI = 1.61-12.85]) and those who were physically inactive were less likely to drink (aOR = 0.58 [95% CI = 0.42-0.82]). Current drinking and physical inactivity contributed to a higher likelihood of smoking (aOR = 4.31 [95% CI = 1.35-13.73] and 6.34 [95% CI = 1.65-24.34]). Thyroid cancer survivors had better health behaviors than the non-cancer controls. However, some survivors still had unhealthy lifestyles, especially displaying a clustering of unhealthy behaviors. Thus, health behavior promotion through medical intervention is important for thyroid cancer survivors.
The New York Times’ presentation of Iran’s government in news articles before and after the nuclear deal

By applying framing analysis to the New York Times’ news articles, this study shows that during the nuclear negotiations and after the deal, Iran and its officials were framed with Orientalist stereotypes. The Foreign Minister was positively presented for his Western attributes and framed as an enemy for his affiliations with the government. President Rouhani’s framing discredited him by highlighting the despotic nature of Iran, and the Leader was presented as an irrational despot.
Childhood experiences pursue adulthood for better and worse: a qualitative study of adults' experiences after growing up with a severely mentally ill parent in a small-scale society

Background Growing up with a severely mentally ill parent can impact on subsequent adult life, and it can be extra challenging in a society with a small population, known as a small-scale society. Life in a small-scale society is characterised by multiple close relationships, lack of anonymity and a conservative attitude towards normal behaviour. Aims To look at the impact of growing up with a mentally ill parent on adult life in a small-scale society. Methods Data from semistructured interviews with 11 adult children of severely mentally ill parents were reanalysed and subjected to secondary analysis. Results The additional analysis resulted in four central themes: ‘becoming open and courageous’, ‘seeking and giving help’, ‘feeling uncertain and different’ and ‘being resilient and sensitive’. These were conflated into an overarching theme: ‘childhood experiences track into adulthood for better and worse’. The themes elucidate a diverse big picture and encompass positive and challenging features of adult life in a small-scale society. Conclusions The study ends with recommendations for the early establishment of collaboration and family-focused interventions with mentally ill parents and their children.
Ecological Factor Research on the Growth and Induction of Spores Release in Enteromorpha Prolifera(Chlorophyta)

After the investigations on several ecological factors of growth and spores release of Enteromorpha prolifera ( Mller ) J. Ag. , the suitable ranges and the optimum ranges of each factor have been confirmed. According to our study, the suitable salinity and temperature ranges for growth and spores release are 16～40 and 12～40, 10 ℃ ～30 ℃ and 15 ℃ ～ 35 ℃. The suitable light intensity and pH ranges for growth and spores release is the same at more than 9 μmol/m2s and 6～10. In the aspects of the optimum conditions, the salinity, temperature and light intensity ranges for growth and spores release are 24～28 and 28～40, 20 ℃ ～25 ℃ and 20 ℃ ～35 ℃, more than 18 μmol/m2s and more than 36 μmol/m2s. The optimum pH ranges for growth are 8～9, and the same for spores release. The suitable ranges of each ecological factor for growth are the same as for the spores release, while the optimum ranges of them show obvious distinction.
Early Auditory Experience Modifies Neuronal Firing Properties in the Zebra Finch Auditory Cortex

Songbirds learn to sing much as humans learn to speak. In zebra finches, one of the premier songbird models, males learn to sing for later courtship through a multistep learning process during the developmental period. They first listen to and memorize the song of a tutor (normally their father) during the sensory learning period. Then, in the subsequent sensory-motor learning phase (with large overlap), they match their vocalizations to the memorized tutor song via auditory feedback and develop their own unique songs, which they maintain throughout their lives. Previous studies have suggested that memories of tutor songs are shaped in the caudomedial nidopallium (NCM) of the brain, which is analogous to the mammalian higher auditory cortex. Isolation during development, which extends the sensory learning period in males, alters song preference in adult females, and NCM inactivation decreases song preference. However, the development of neurophysiological properties of neurons in this area and the effect of isolation on these neurons have not yet been explained. Here, we performed whole-cell patch-clamp recording on NCM neurons from juvenile zebra finches during the sensory learning period, 20, 40, or 60 days post-hatching (DPH) and examined their neurophysiological properties. In contrast to previous reports in adult NCM neurons, the majority of NCM neurons of juvenile zebra finches showed spontaneous firing with or without burst firing patterns, and the percentage of neurons that fired increased in the middle of the sensory learning period (40 DPH) and then decreased at the end (60 DPH) in both males and females. We further found that auditory isolation from tutor songs alters developmental changes in the proportions of firing neurons both in males and females, and also changes those of burst neurons differently between males that sing and females that do not. Taken together, these findings suggest that NCM neurons develop their neurophysiological properties depending on auditory experiences during the sensory song learning period, which underlies memory formation for song learning in males and song discrimination in females.
Understanding the Effects of Deep Space Radiation on Nervous System: The Role of Genetically Tractable Experimental Models

Space agencies are working to establish a permanent human presence on the moon and to reach Mars within the next few decades. In these missions, astronaut crew members will be exposed to moderate doses of the highly energetic particles that compose galactic cosmic rays (GCR). GCR consist of alpha particles, protons, and high atomic number ions, stripped of their electrons (HZE), which are relatively rare, but are also highly ionizing. HZE are particularly damaging to biological tissues, because they can penetrate to much deeper layers of shielding materials than gamma rays and x-rays and produce within tissues long ionization tracks, with strongly clustered damage to information molecules. The consequences of such damage to central nervous system health is a major concern. A strong development of new knowledge and models, which may help to predict the risk of individual astronauts, is an absolute requirement in this field. Genetically tractable animal models offer unique opportunities to directly investigate the genetic and molecular events that may affect the biological response to GCR and related radiation.
High resolution paleo-environmental changes during the Sapropel 1 in the North Ionian Sea, central Mediterranean

High-resolution paleoceanographic reconstruction of surface water properties during the most recent Sapropel event (S1) has been carried out by means of quantitative analyses of planktonic foraminiferal assemblages, planktonic foraminiferal oxygen isotopes (δ18O) and XRF elemental data from a 655 m depth core recovered in the North Ionian Sea. The results show that the S1 interval presents two distinctive warm phases (S1a and S1b), separated by a cold interruption event (S1i). High resolution faunal and geochemical analyses allow to identify two sub-phases within S1a interval, the oldest one has similar characteristics to S1b interval while the youngest sub-phase has less stratified surface waters with relatively lower nutrient content. The high abundance of Globigerinoides ruber white variety opposite to the low percentages of Neogloboquadrina pachyderma during the pre-S1 phase suggests that the onset of surface waters stratification occurred prior to the beginning of Sapropel deposition, acting as a pre-conditioning phase. Paleo-productivity proxies indicate that the deposition of S1 initiated after an increase in nutrient content, potentially related to increased fluvial inputs. Based on the integrated ecological interpretation of our records we argue that S1a and S1b are characterized as warm, stratified and nutrient rich surface waters in the Ionian Sea, while proxies related to oxygen content indicate dysoxic deep waters linked to a combination of the high nutrient content and stratified water column. The S1 interruption phase is characterized by the entrance of colder waters that caused mixing of the stratified water column and re-ventilation of the deep dysoxic waters.
Intraday Variability and Trading Volume: Evidence from National Stock Exchange

In this article, we investigate patterns in returns, volume and volatility and analyse the volume–return relationship using tick-by-tick data from the Indian equity market. Based on descriptive measures and regression frameworks, we document three important findings. First, we report unusually high volatility, trading volume and number of trades during the opening and closing minutes of the market depicting a ‘U’-shaped curve, implying high market activity during these periods. Second, while accounting for trading volume, we observe that volatility is not significantly different between mid-day period and evening period as compared to the normal ‘U’ curve. Finally, we document a significant positive relationship between intraday volume and price movements controlling for microstructure effects. The impact of positive returns on trading volume is higher than the impact of negative returns, implying the presence of return–volume asymmetry in the Indian market. JEL Codes: G12, G15
Students’ Perspectives on the Master’s Degree in Music Education

The purpose of this study was to investigate currently enrolled students’ perceptions of the master’s degree in music education (MME). A national sample of 136 MME students completed a web-based questionnaire. The most common motivations for enrolling in MME programs were to become a better teacher, to get a higher salary, to gain academic stimulation through graduate-level coursework, and to create a possible pathway to doctoral study in the future. However, motivational differences were evident based on respondents’ degree format (academic year, online, summer, or hybrid). Respondents indicated that they learned about research primarily through reading and discussing research articles, and learned about pedagogy primarily through reading articles on pedagogy/teaching strategies and watching and reflecting on personal teaching videos. I explore implications for music teacher education given these findings as well as respondents’ reports of MME program strengths and areas needing improvement.
Amino Acid Composition of Grape (Vitis vinifera L.) Juice in Response to Applications of Urea to the Soil or Foliage

Applications of nitrogen to vineyard foliage or soil at veraison can improve grape juice yeast assimilable nitrogen concentrations and may prevent the excessive vine growth, delayed maturity, and adverse changes in fruit properties sometimes associated with high applications of N earlier in the growing season. However, the consequences of late-season foliar- and soil-applied nitrogen for grape juice yeast assimilable nitrogen (YAN) and, specifically, grape juice amino acid profiles have rarely been directly compared. Over two years in drip-irrigated Merlot and Pinot gris vineyards, grape juice amino acid concentrations were measured from vines to which urea had been applied three times around veraison at 3.8 g N/vine to either the foliage or the soil surface. Foliar-applied urea (applied as a 2% w/v solution) was usually more effective at boosting grape juice ammonium and amino acid concentrations, although soil-applied urea improved some grape juice amino acids at the Pinot gris site. Changes in the amino acid profiles of grape juice, observed in response to foliar N applications but not soil N applications, may have implications for wine quality. Applications of 15N-labeled urea at the Pinot gris site demonstrated that a greater percentage of fertilizer N was incorporated into grape juice amino acids when urea was applied to the foliage than when it was applied to the soil surface. Late-season foliar applications of urea are a reliable, efficient, and effective method of improving grape juice YAN. Further work is required to examine how treatment effects vary among sites and cultivars under different management practices and to understand the implications of altered grape juice amino acid profiles for wine quality.
Level and determinants of job satisfaction among Saudi physicians working in primary health-care facilities in Western Region, KSA

Introduction: Job satisfaction is an important factor influencing the health of workers and is directly related to quality of care. Objectives: To assess the level of job satisfaction and factors contributing to dissatisfaction of Saudi physicians in primary health care centers in Jeddah. Methods All Saudi physicians working in primary health care centers in a city in the Western region, KSA, were included in this web-based survey using the “Job Satisfaction Survey” questionnaire adopted by Paul E. Spector (1994). In addition, socio-demographic data (age, sex, marital status, work facilities, qualification, work experience and income) were collected (response rate 83% ). Results: 63% of the physicians are satisfied about the nature of work in the primary health care centers, while 25.2% were satisfied about the payment. A large proportion of respondents were dissatisfied about the contingent rewards and fringe benefits (83.2%, 76.5%respectively). None of the specialists were satisfied about the work compared to 10.6% of the general practitioners. Conclusion: Slightly less than half of the physicians are satisfied. Financial incentives (contingent rewards and fringe benefits) impose a negative impact on job satisfaction for primary care physicians. On the other side, the nature of work has had the most positive impact on job satisfaction. Specialists were found to have less satisfaction. Investing in the physicians' satisfaction about the nature of work in the primary healthcare facilities to create a sense of ownership that would be reflected on the quality of patient care is required. There is a need to conduct further studies on the fiscal privileges that lead to job satisfaction among physicians.
The Source of the Legislative Professionalism Advantage: Attracting More Knowledgeable Candidates

Legislators who know their constituents’ opinions are more likely to be successful in providing substantive representation on issues of the day. However, previous work suggests that state legislators and candidates commonly misestimate their constituents’ preferences. Some of that work also finds that candidates and current incumbents in highly professionalized legislatures are less likely to misestimate constituent opinion. We investigate why this professionalism advantage exists. We use a Blinder–Oaxaca decomposition to determine how much of the professionalism advantage can be attributed to three sources: attracting knowledgeable candidates, fostering legislator knowledge in office, and retaining incumbents. We apply the decomposition to data on candidates’ perceptions of public opinion from the 2014 National Candidate Survey. Fostering knowledge in office and retaining incumbents are not responsible for the professionalism advantage. We find evidence that the professionalism advantage occurs because higher professionalism legislatures attract more knowledgeable nonincumbent candidates.
Comparison of morphological and DNA metabarcoding analyses of diets in exploited marine fishes

: Ecosystem-based management (EBM) is a framework for managing marine re -sources. EBM strategies can be evaluated with ecosystem models that represent functional components of ecosystems, including anthropogenic factors. Foodwebs are at the core of ecosystem models, but because dietary data can be difficult to obtain, they are often coarsely characterised. High-throughput DNA sequencing (HTS) of diets is a rapid way to parameterise foodwebs at enhanced taxonomic resolution, and potentially, to optimise the functioning of ecosystem models. We evaluated the relative merits of microscopic and HTS analyses of the diets of 8 fish species harvested in Australia’s most intensive fishery, viz. the southeast trawl fishery. We compare the taxonomic resolution and phylogenetic breadth of diets yielded by these methods and include a comparison of 3 DNA barcoding markers (mtDNA COX1 Minibar, mtDNA 16S Chord-cephA, nDNA 18S Bilateria). Using paired individual gut samples (n = 151), we demonstrate that HTS typically identified similar taxon richness but at significantly higher taxonomic resolution than microscopy. However, DNA barcode selection significantly affected both the resolution and phylogenetic breadth of estimated diets. Both COX1 Minibar and 16S Chord-cephA barcodes provided higher taxonomic resolution than morphological analysis, but the resolution varied between taxonomic groups primarily due to availabilities of reference data. However, neither barcode recovered the full dietary spectrum revealed by the 18S Bilateria barcode. HTS also revealed the presence of dietary items not previously recorded for target species, and diverse parasite assemblages. We conclude that HTS has the potential to improve structure and function of ecosystem models and to facilitate best-practice EBM.
Oral and Fecal Microbiome in Molar-Incisor Pattern Periodontitis

In order to improve our understanding on the microbial complexity associated with Grade C/molar-incisor pattern periodontitis (GC/MIP), we surveyed the oral and fecal microbiomes of GC/MIP and compared to non-affected individuals (Control). Seven Afro-descendants with GC/MIP and seven age/race/gender-matched controls were evaluated. Biofilms from supra/subgingival sites (OB) and feces were collected and submitted to 16S rRNA sequencing. Aggregatibacter actinomycetemcomitans (Aa) JP2 clone genotyping and salivary nitrite levels were determined. Supragingival biofilm of GC/MIP presented greater abundance of opportunistic bacteria. Selenomonas was increased in subgingival healthy sites of GC/MIP compared to Control. Synergistetes and Spirochaetae were more abundant whereas Actinobacteria was reduced in OB of GC/MIP compared to controls. Aa abundance was 50 times higher in periodontal sites with PD≥ 4 mm of GC/MIP than in controls. GC/MIP oral microbiome was characterized by a reduction in commensals such as Kingella, Granulicatella, Haemophilus, Bergeyella, and Streptococcus and enrichment in periodontopathogens, especially Aa and sulfate reducing Deltaproteobacteria. The oral microbiome of the Aa JP2-like+ patient was phylogenetically distant from other GC/MIP individuals. GC/MIP presented a higher abundance of sulfidogenic bacteria in the feces, such as Desulfovibrio fairfieldensis, Erysipelothrix tonsillarum, and Peptostreptococcus anaerobius than controls. These preliminary data show that the dysbiosis of the microbiome in Afro-descendants with GC/MIP was not restricted to affected sites, but was also observed in supragingival and subgingival healthy sites, as well as in the feces. The understanding on differences of the microbiome between healthy and GC/MIP patients will help in developing strategies to improve and monitor periodontal treatment.