Miracle-dz/UniFAR-FTUs huggingface dataset:
Outcome after SRT of brain metastases 3a: RELATIONSHIP BETWEEN VOLUME, DOSE AND LOCAL CONTROL IN STEREOTACTIC RADIOSURGERY OF BRAIN METASTASIS RICHARD MOLENAAR, RUUD WIGGENRAAD, ANTOINETTE VERBEEK-DE KANTER, ROB WALCHENBACH AND CHARLES VECHT

The aim of this study is to analyse the efficacy of linear accelerator stereotactic radiosurgery (SRS) on prognostic factors, local control rate and survival in patients with brain metastasis. Patients with either a single metastasis or up to 4 multiple brain metastases with a maximum tumour diameter of 40 mm for each tumour and a Karnofsky Performance Status (KPS) ≥70 were eligible for SRS. SRS was applied to 150 lesions in 86 consecutive patients with a median age of 60 years (median 1 and mean 1.7 lesions per patient, mean KPS 86). Median overall survival was 6.2 months after SRS and 9.7 months from diagnosis of brain metastasis. Multivariate analysis revealed that a KPS of 90 or more (p = 0.009) and female sex (p = 0.003) were associated with a longer survival. Radiation dose ≤15 Gy (p = 0.017) and KPS <90 (p = 0.013) were independent predictors of a shorter time to local failure. Five patients showed evidence of radionecrosis with a median survival of 14.8 months. Addition of WBRT neither led to improvement of survival nor to improvement of local control. Improved local control following SRS for brain metastases was associated with KPS ≥90, a radiation dose >15 Gy and a PTV <13 cc. The potential of hypofractionated stereotactic radiotherapy (SRT) for brain metastases of larger volume warrants further study.
Probing the Individual and Synergistic Effect of Calcium and Zinc against Lead Induced Hematological Alterations and Oxidative Stress

Introduction: Lead (Pb) exposure is a worldwide unavoidable environmental problem because of its presence in various useable appliances causing severe health problems. Different minerals like Zinc (Zn) and Calcium (Ca) are known to exert competitive behavior with Pb because of structural analogy thus hinder Pb absorption in blood. Objective: To determine individual as well as synergistic potential of Zn and Ca in inhibition of Pb induced adverse impact on rat hematology and antioxidant enzymes. Methodology: In controlled environment, Sprague dawley rats received Lead acetate 20 mg/kg of Body Weight (bw), zinc sulphate 20 mg/kg bw and calcium carbonate 7500 mg/kg bw with different combinations via nasogastric tube feeding for 35 days. Blood samples collected from rats were tested for complete blood count and antioxidant enzymes in blood. Results: Lead exposure significantly decreased the red blood cells, hemoglobin, hematocrit, monocytes, granulocytes, platelet count (P<0.01) white blood cells and red blood cell distribution width (P<0.05). Antioxidant enzymes including superoxide dismutase and catalase were also found significantly reduced (P<0.01) after Pb exposure. These alterations in hematological and antioxidant enzymes concentrations were lessened by Zn, Ca and Zn+Ca supplementation, with Zn being more effective than others. Conclusion: Results of this study clearly shows that Zn and Ca either alone or in combination possess ameliorative potential against the hallmarks of Pb induced oxidative stress but Zn alone showed greater impact than Ca and Zn+Ca supplementation. So it can be inferred that Zn and Ca supplementation could act as potential preventive strategy to hinder Pb induced hematological alteration and oxidative stress.
The Effects of Cosmopolitanism on Consumer Ethnocentrism, Brand Origin Identification and Foreign Product Purchases

Current research paperexamines cosmopolitanism as a factor underlying consumer decisions to purchase foreign rather than domestic products in three categories of products: alcohol products, clothes and furniture. In conceptual model two other theoretical constructs for measuring foreign product purchasesare included: ethnocentrism and brand origin identification. The measurement model is examined using a data set of 271 and 261 adult consumers in Estonia and Slovenia. Data is tested via structural equation modeling. The study results confirm the strong and direct effect of consumer cosmopolitanism in foreign product purchasesand brand origin identification is confirmed as a mediating variable between consumer ethnocentrism and foreign product purchases.On the other hand, direct relationship between cosmopolitanism and brand origin identificationis not supported by conducted study.
The Effects of Progesterone Administration in Mice During Pregnancy on Ovarian Development and Anogenital Distance of the Offspring

Progesterone is highly used in pregnant women as therapeutic agent to maintain and support pregnancy. To explore the effects of progesterone usage allover gestation till 7days postnatally on mice offspring ovaries development and anogenital distance. Ten pregnant mice were equally divide into control group that was injected with sesame oil which is used as a solvent for progesterone and treated group that is daily intraperitoneally injected with progesterone (dissolved in sesame oil 1:10) at dose 10.2mg/kg (the equivalent human dose) all through gestation till7day postnatal then sacrificed and measuring the anogenital distance (the distance between anus and genital papilla). Histological slides were prepared, and Diameters of the ovary, primary oocyte and primordial follicles were measured and histopathological changes analysis was done. Progesterone administration cause significant increment (p > 0-05) in anogenital distance, significant decrement in primary oocyte diameter and primordial follicle diameter, with no significant difference in the ovary diameter. Histopathological changes were seen as hemorrhage, detachment of follicular cells from basement membrane with irregular arrangement and thickening or death of follicular cells, pyknosis of primary oocytes and vacculation. Stromal cells degeneration. The current study revealed that progesterone injection of mice with equivalent human dose during pregnancy is embryotoxic and teratogenic, may alter the female reproductive performance with virilizing the female genitalia. The benefit of progesterone as a therapies need to be proven before recommended as supportive treatment during pregnancy. Experimental article (J Int Dent Med Res 2019; 12(4): 1665-1670)
Nursing education in humanized care

Objective: To evaluate the effect of an educational intervention for the adequate use of the Dignified Treatment indicator by the nursing staff before the care of hospitalized patients. Methods: Pre-experimental analysis performed from February to March of 2017 in a public hospital in San Luis Potosí Mexico, with 37 nurses. In the first stage, a diagnostic evaluation of knowledge was elaborated. In the second, an education program was implemented for the proper use of the decent treatment indicator. In the third, nursing knowledge was evaluated and the before and after tests were compared by the t-Student parametric test. Results: For the diagnostic stage, 97% of nursing staff had a low level of knowledge. After implementing the program, 80% of the team increased their level. Conclusions: The educational intervention increased the knowledge about the use of the Dignified Treatment indicator.
Design ofWidebandMIMOCar-toCar Channel Models Based on the Geometrical Street ScatteringModel

We propose a wideband multiple-input multiple-output (MIMO) car-to-car (C2C) channel model based on the geometrical street scattering model. Starting from the geometrical model, a MIMO reference channel model is derived under the assumption of single-bounce scattering in line-of-sight (LOS) and non-LOS (NLOS) propagation environments. The proposed channel model assumes an infinite number of scatterers, which are uniformly distributed in two rectangular areas located on both sides of the street. Analytical solutions are presented for the space-time-frequency cross-correlation function (STF-CCF), the two-dimensional (2D) space CCF, the time-frequency CCF (TF-CCF), the temporal autocorrelation function (ACF), and the frequency correlation function (FCF). An efficient sum-of-cisoids (SOCs) channel simulator is derived from the reference model. It is shown that the temporal ACF and the FCF of the SOC channel simulator fit very well to the corresponding correlation functions of the reference model. To validate the proposed channel model, the mean Doppler shift and the Doppler spread of the reference model have been matched to real-world measurement data. The comparison results demonstrate an excellent agreement between theory and measurements, which confirms the validity of the derived reference model. The proposed geometry-based channel simulator allows us to study the effect of nearby street scatterers on the performance of C2C communication systems.
Morphological characterization and selection for high yielding and powdery mildew resistant pea (Pisum sativum) lines

Twenty lines of Pisum sativum particularly developed for high yield and resistant to powdery mildew were evaluated along with two parents (Falloner and 11760-3ER) and two checks (Climex and a local cultivar) with the objectives to determine morphological characterization, yield potential and resistance to powdery mildew. On the basis of one way cluster, the 24 lines were mainly grouped into four clusters, especially on the vegetative and yield contributing traits. It was observed that the tall and high yielding lines were grouped in cluster-III while the dwarf and high yielding lines were grouped in cluster-IV. Analysis of variance (ANOVA) showed significant difference (p 1.0) contributed more than 80% variability among the materials.
The relationships between person-organization fit, psychological climate adjustment, personality traits, and innovative climate: Evidence from Taiwanese high-tech expatriate managers in Asian countries

The primary objective of this study is to integrate basic theoretical background to define and develop a new research framework in order to investigate the relationships between person-organization fit (POF), psychological climate adjustment, personality traits, and innovative climate. This study surveyed 432 Taiwanese high-tech expatriate managers in Asian countries. The results of this study are summarized as follows: (1) POF, individual perception of psychological climate adjustment and individual employee’s personality traits will be positively related to an organization’s innovative climate; and (2) Psychological climate adjustment and personality traits will positively moderate the relationship between POF and an organization’s innovative climate. Key words: Innovative climate, person-organization fit (POF), personality traits, psychological climate adjustment.
Cosmological N-body simulations with a large-scale tidal field

In this paper we carry out anisotropic "separate universe" simulations by including a large-scale tidal field in the N-body code \textsc{gadget}4 using an anisotropic expansion factor $A_{ij}$. We use the code in a pure \textit{particle-mesh} (PM) mode to simulate the evolution of 16 realizations of an initial density field with and without a large-scale tidal field, which are then used to measure the \textit{response function} describing how the tidal field influences structure formation in the linear and non-linear regimes. Together with the previously measured response to a large scale overdensity, this completely describes the nonlinear matter bispectrum in the squeezed limit. We find that, contrary to the density response, the tidal response never significantly exceeds the large-scale perturbation-theory prediction even on nonlinear scales for the redshift range we discuss. We develop a simple halo model that takes into account the effect of the tidal field and compare it with our direct measurement from the anisotropic N-body simulations.
Metaphors of Change in the Context of Eating Disorders: Bridging Understandings with Girls’ Perceptions

Although the use of metaphor is not a new strategy in counselling or research, the literature has not fully addressed individuals’ metaphors of change and how these relate to the counselling process. Using a narrative methodology, we examined the metaphors of change provided by girls recovering from eating disorders. These rich descriptions highlighted the similarities and differences in how the girls viewed change. Furthermore, this analysis of metaphors gave us a sense of what can be learned about girls’ views of identity and agency. It is apparent that there are important implications when using metaphors in the counselling process.
Factors Influencing Upcycling for UK Makers

Changing consumer behaviour can reduce environmental impacts. Upcycling is one of the understudied yet promising, environmentally sustainable behaviours that has the potential to contribute to the reduction of waste and greenhouse gas emissions. This paper addresses this knowledge gap by exploring factors influencing upcycling for UK makers. The study employed a survey based on Triandis’s theory of interpersonal behaviour and Ajzen’s theory of planned behaviour. The survey results revealed key determinants of upcycling as attitude, intention, and subjective norm, and demographic characteristics of people who are more likely to upcycle frequently as females aged 30+ working in art and design. The paper further discusses the theoretical and practical implications of the study.
The Relationship Between Skeletal and Dental Characteristics in Patients with Class II Malocclusion

The aim of this study was to determine the relationship between dental and skeletal characteristic of Javanese ethnic patient with Class II skeletal malocclusion. This was a descriptive analytic research using lateral cephalograms and dental casts of 65 Javanese ethnic patients with skeletal class II malocclusion. Lateral cephalograms for each patient was traced with digital cephalometric to measure skeletal parameters (SNA, SNB, ANB, and Y Axis) and dental parameters (overbite, overjet, dental arch shape, width and length of dental arch, interpremolar and intermolar height, interpremolar and intermolar width) were measured also using vernier calliper. The data obtained were analyzed using Pearson correlation test with p < 0.05. The highest frequency of maxillary and mandibular denture arch shape were v-shape. There was a correlation between patterns of skeletal class II and dental characteristics, SNA was positively correlated with maxillary interpremolar width and SNB was negatively correlated with mandibular interpremolar height. There are various skeletal and dental characteristics that are correlated with DeutroMalayu races (Javanese ethnic) which makes dentocraniofacial complexity in class II skeletal malocclusion. Clinical article (J Int Dent Med Res 2019; 12(4): 1421-1425)
HOW SME UNIQUENESS AFFECTS CAPITAL STRUCTURE: EVIDENCE FROM A 1994-1998 SPANISH DATA PANEL

The principal aim of this paper is to test how firm characteristics affect Small and Medium Enterprise (SME) capital structure. We carry out an empirical analysis over a panel data of 6482 non? financial Spanish SMEs along the five-year period 1994? 1998, modelling the leverage ratio as a function of firm specific attributes hypothesized by capital structure theory. Our results suggest that non? debt tax shields and profitability are both negatively related to SME leverage, while size, growth options and asset structure influence positively on SME capital structure; they also confirm a maturity matching behaviour in this firm group. El principal objetivo de este trabajo reside en estudiar como determinadascaracteristicas empresariales afectan a la estructura de capital de la Pequena y MedianaEmpresa (PYME). Para lograr este objetivo, se lleva a cabo un analisis empirico sobre unpanel de 6482 PYMEs no financieras espanolas a lo largo del lustro 1994? 1998. El ratio deendeudamiento se contempla como una funcion de aquellos atributos especificos de lasempresas que han sido identificados por la teoria de la estructura de capital. Los resultadosobtenidos sugieren que, tanto los escudos fiscales alternativos a la deuda como la rentabilidadempresarial, se encuentran negativamente relacionados con el endeudamiento de las PYMEs,mientras que el tamano, las oportunidades de crecimiento y la estructura de los activosinfluyen de forma positiva en la estructura de capital de las PYMEs. Estos resultados tambienconfirman un comportamiento tendente a la conciliacion de vencimientos de activos y pasivosen este grupo empresarial.
Estimates of Surface and Subsurface Boundary Current Transport Around Australia

A 15 year (2000–2014) simulation of the oceans around Australia, with the shelf-scale model ozROMS, was used to estimate the mean, seasonal, and interannual variability of the surface and subsurface boundary currents and associated inflows. The simulation clarified some previous points of uncertainty and provided new information previously unknown and this is listed here. In the Indian Ocean, flow through the Timor Passage was linked to southeast Australia through the Holloway (HLC), Leeuwin (LC), South Australian (SAC), and Zeehan (ZC) Currents. The main inflows were from the Indonesian Throughflow and Eastern Gyral Current in the north whilst the central and southern branches of the South Indian Counter Current (SICC) provided major (>60%) inflows to the LC in the west. The HLC at North-west Cape was at a maximum in April–May and its annual cycle accounted for 70% of the seasonal variance of LC, SAC, and ZC. In the Pacific Ocean, the northern branches of the South Equatorial Current were the main inputs to initiate the Hiri and East Australian (EAC) Currents flowing north and south, respectively, at ∼15°S. Inflow from the South Caledonia Jet to the EAC was ∼35%. The Flinders Current (FC) contributed to the Leeuwin Undercurrent (LU) directly as a northward flow and LU was enhanced from inflow from the subsurface southern SICC in the west (∼32–33°S). The majority of LU flowed westward offshore between 24 and 29°S while ∼25% continued northward to the northwest shelf. All Australian surface boundary currents systems were enhanced during the 2011–2013 La Nina.
Clifford congruences on perfect semigroups

A congruence ρ on a semigroup S is called perfect if (aρ)(bρ) = (ab)ρ for all a, b ∈ S, as sets, and a semigroup S is said to be η-idempotent-surjective (respectively perfect) if every η-class of S contains an idempotent of S, where η is the least semilattice congruence on S (respectively if each congruence on S is perfect). We describe the least Clifford congruence ξ on an η-idempotentsurjective perfect semigroup S. In addition, a characterization of all Clifford congruences on such a semigroup is given. Furthermore, we find necessary and sufficient conditions for ξ to be idempotent pure or E-unitary. Moreover, we give a full description of all USG-congruences on an η-idempotent-surjective perfect semigroup S. In fact, we show that each USG-congruence θ on S is the intersection of a semilattice congruence ε and a group congruence υ (and vice versa), and this expression is unique. Also, S/θ ∼= S/ε × S/υ. Finally, we investigate the lattice of Clifford congruences on a semigroup S which is a semilattice S/η of E-inversive semigroups eη (e ∈ ES).
Measurement of Technical Efficiency in Public Education: A Stochastic and Nonstochastic Production Function Approach

This paper uses both the stochastic and nonstochastic production function approach to measure technical efficiency in public education in Utah. The stochastic specification estimates technical efficiency assuming half normal and exponential distributions. The nonstochastic specification uses two-stage data envelopment analysis (DEA) to separate the effects of fixed inputs on the measure of technical efficiency. The empirical analysis shows substantial variation in efficiency among school districts. Although these measures are insensitive to the specific distributional assumptions about the one-sided component of the error term in the stochastic specification, they are sensitive to the treatment of fixed socioeconomic inputs in the two-stage DEA.
The sources of phonological knowledge: a cross-linguistic perspective

Les donnees experimentales, obtenues pour des enfants apprenant des langues cibles differentes, se caracterisent par des similitudes et des differences. Elles montrent egalement une continuite entre la perception de la parole et les premieres vocalisations. Ceci invite a considerer que la mise en relation precoce entre les formes du babillage et les formes des mots entendus est a la base des premieres unites produites qui au depart sont structurellement tres limitees mais relativement correctes. C’est cette conception que nous retenons pour rendre compte aussi bien des similarites que des differences dans la forme des premiers mots produits pour des langues cibles differentes. Des mesures de la duree de consonnes mediales dans la parole adulte et dans les mots des enfants dans des langues ou la longueur consonantique a une valeur phonologique vs phonetique differente permettent d’etablir que la mise en place des representations phonologiques repose sur (1) l’apprentissage direct de frequences de distribution et (2) l’apprentissage du lexique, qui suffit a expliquer le developpement des contrastes phonologiques pertinents pour chaque langue-cible. Selon nous, les systemes complementaires de memoire implicite et explicite permettent de rendre compte des deux types d’apprentissage. Nous defendons donc le point de vue selon lequel une exposition reguliere a l’environnement linguistique suffit pour expliquer la construction de la connaissance phonologique sans avoir recours a une connaissance linguistique innee ni de la Grammaire Universelle.
Ensemble prediction and the role of higher order moments in atmospheric regime transitions

We investigate the role of higher order moments in ensemble prediction studies using bred initial perturbations, ensemble averaged direct numerical simulations (DNS), and an inhomogeneous statistical closure model for 2D turbulence interacting with Rossby waves, mean fields and topography. Our closure methodology extends the previous work of Epstein [1969, Tellus 21 ] and Fleming [1971, Mon. Wea. Rev. 99 ], based on a cumulant discard hypothesis, to include all moments higher than second order. Unlike previous quasi-normal closures the quasi-diagonal direct interaction approximation (QDIA) model does not need to be Markovianized to guarantee positivity of energy and enstrophy and is valid for both strongly non-Gaussian and strongly inhomogeneous flows. In addition the QDIA does not become unbounded for long integration periods as is the case for the eddy damped quasi-normal method [Fleming, 1971, Mon. Wea. Rev. 99 ]. We compare the QDIA to DNS for Northern Hemisphere flow during early November 1979 when a large and persistent high-low blocking dipole formed over the Gulf of Alaska. The formation and decay of atmospheric blocking events has typically been associated with a loss of predictability induced by large scale flow instabilities. Results from the QDIA statistical closure and DNS are shown to be in close agreement even throughout periods of block formation. We also examine distinct regimes of error growth arising from second and higher order effects.