Miracle-dz/UniFAR-FTUs huggingface dataset:
Non-Invasive Classification of Alzheimer's Disease Using Eye Tracking and Language

Alzheimer’s disease (AD) is an insidious progressive neurodegenerative disease resulting in impaired cognition, dementia, and eventual death. At the earliest stages of the disease, decline in multiple cognitive domains including speech and eye movements occurs, and worsens with disease progression. Therefore, investigating speech and eye movements is promising as a non-invasive method for early classiﬁcation of AD. While related work has investigated AD classiﬁcation using speech collected during spontaneous speech tasks, no prior research has studied the utility of eye movements and their combination with speech for this classiﬁcation task. In this paper, we present classiﬁcation experiments with speech and eye movement data collected from 68 memory clinic patients (with a diagnosis of AD, mixed
THE EFFECT OF EMPOWERING LEADERSHIP ON INTRINSIC MOTIVATION: THE ROLE OF PSYCHOLOGICAL EMPOWERMENT AS A MEDIATION

This research aims to investigate the human resources managment within the government which requires a reliable and competent leadership. A leadership categorized as the concept of empowering when the leader shares direction, a support system, friendly, synergizing, and providing exemplary examples to his subordinates. Employees who feel empowered by the leader would increase their motivation in work. This would increase psychological side of the employee’s cognitions such as a meaningfulness, the competence, a self-determination, and the effect. This research is focused on the process of testing hypotheses and is aimed to examine the effect of empowering leadership’s motivation in the field of work. It is mediated by psychological empowerment. The data used in this study was a questionnaire. This study was used four-stage hypothesis test of Baron and Kenny (1986). The result indicates that empowering leadership has a positive effect on intrinsic motivation , and psychological empowerment partially mediates the positive effect of empowering leadership in supporting intrinsic motivation.
Hess-2019-242-RC 1 Reply to Hessel Winsemius ’ comments

Land surface models combined with river routing models are widely used to study the continental part of the water cycle. They give global estimates of water flows and storages but they are not without non-negligible uncertainties among which inexact input parameters play a significant part. The incoming Surface Water and Ocean Topography (SWOT) satellite mission, with a launch scheduled for 2021 and with a required lifetime of at least three years [R#1-M#1], will be dedicated to the measuring of water surface elevations, widths and surface slopes of rivers wider than 100 meters, at a global scale. SWOT 5 will provide a significant amount of new observations for river hydrology and maybe combined, through data assimilation, with global-scale models in order to correct their input parameters and reduce their associated uncertainty. Comparing simulated water depths with measured water surface elevations remains however a challenge and can introduce within the system large bias. A promising alternative for assimilating water surface elevations consists of assimilating water surface elevation anomalies which do not depend on a reference surface [R#2-M#1][R#3-M#1]. The objective of this study is to present a data assimilation 10 platform based on the asynchronous ensemble Kalman filter (AEnKF) that can assimilate synthetic SWOT observations of water depths and water elevation anomalies [R#2-M#1] to correct the input parameters of a large scale hydrologic model over a 21-day time window. The study is applied to the ISBA-CTRIP model over the Amazon basin and focuses on correcting the spatial distribution of the river Manning coefficients. The data assimilation algorithm, tested through a set of Observing System Simulation Experiments (OSSE), is able to retrieve the true value of the Manning coefficients within one assimilation 15 cycle much of the time (basin-averaged Manning coefficients RMSEn is reduced from 33% to [1%-10%] after one assimilation cycle) and shows promising perspectives with assimilating water anomalies [R#2-M#1] (basin-averaged Manning coefficients RMSEn is reduced from 33% to [1%-2%] when assimilating water surface elevation anomalies over one year) which allows us to overcome the issue of unknown bathymetry [R#3-M#1].
Stock discrimination of European conger eel (Conger conger L.) using otolith stable isotope ratios

European conger eel (Conger conger) is a common and widely distributed fish in the NE Atlantic and Mediterranean. Although there is increasing evidence that stocks of European conger eel are in decline, there is little published material on the population structure or management of the species. Stable isotope ratios, namely 18O and 13C, measured by standard mass spectrometric techniques in whole otolith samples of juvenile conger eels sampled in April/May 2006 from NE Atlantic (Azores, Madeira and North Portugal) and Mediterranean (Mallorca) exploited stocks provided location-specific signatures. Isotopic ratios for conger eel were similar to those reported for other marine species ( 18O‰, mean ± SE: 1.64 ± 0.04, 1.87 ± 0.02, 1.26 ± 0.03, 2.41 ± 0.02 and 13C‰: −1.78 ± 0.08, −2.09 ± 0.07, −3.43 ± 0.15, −2.73 ± 0.12, respectively for North Portugal, Azores, Madeira and Mallorca). Relationships between isotopic ratios ( 18O and 13C) and otolith mass were not significant. Seawater temperature could partially explain the differences in 18O of otoliths among the fishery locations. The 18O signatures of the Portuguese mainland coastal specimens were, however, lower than expected values, possibly as a result of the freshwater input of the Douro River located in the vicinity of this fishery area. The inter-site variation of carbon isotopic signatures was likely related to slight differences in diets or DIC of the water. The distinct isotopic signatures suggest low levels of connectivity between the fishing grounds and that conger eels are relatively sedentary during the juvenile phase. Isotopic signatures in the otoliths of C. conger clearly discriminated between the NE Atlantic and the Mediterranean fishery areas providing support for ies as treatment of these fisher
Response of Nagpur mandarin fruit to pre-harvest sprays of gibberellic acid and carbendazim

Effect of pre-harvest application of GA3 (10, 15 and 20 ppm) was studied on physico-chemical characteristics of Nagpur mandarin during holding of fruit on the tree as well as on losses during post-harvest storage at ambient and refrigerated conditions. GA3 treatments (10, 15 and 20 ppm) delayed rind colour development and fruit softening and minimized fruit drop and puffiness during on-tree storage without adverse effect on TSS/acid ratio and fruit productivity in subsequent years. Fruit weight loss was reduced in storage by GA3 treatment, however, results were inconsistent with respect to decay. The pre-harvest treatment with 10 ppm (twice at colour break with 15 days interval) was found to be optimum for on-tree storage upto 1 month beyond normal harvest. Combination of GA3 with carbendazim further reduced fruit drop and storage decay.
The Gender Generator: A Brain-Computer Interface for the Evocation of Gender Dysphoria Symptoms

We present the Gender Generator: A P300-based brain-computer interface (BCI) to explore constructions of gender and temporarily simulate for the user the symptoms of gender dysphoria. Despite recent progress towards gender equality, prejudice and violence against queer and transgender people remains prevalent [1]. Trans-humanists gender theorists propose that technology will allow for a post-gender trans-human future [2]. However, it is evident that introducing prejudice into these future technologies is a prescient issue [8]. We explore this problem through a creative lens by designing a BCI user interface with the explicit goal of evoking the symptoms of gender dysphoria. Using a non-invasive P300 BCI system allows us to examine the users conscious and potentially unconscious decisions regarding their gender expression. By doing this, we hope to encourage people who may not experience gender dysphoria to be empathetic to those that do. In addition, we hope this system will bring attention to potential biases against transgender people we may build into this new technology. We conducted an experiment to evaluate the effectiveness of our system as an empathic tool and interactive art installation.
Implications of Adenylate Metabolism in Hygiene Assessment: A Review

The assessment of a hygienic state or cleanliness of contact surfaces has significant implications for food and medical industries seeking to monitor sanitation and exert improved control over a host of operations affecting human health. Methods used to make such assessments commonly involve visual inspections, standard microbial plating practices, and the application of ATP-based assays. Visual methods for inspection of hygienic states are inherently subjective and limited in efficacy by the accuracy of human senses, the degree of task-specific work experience, and various sources of human bias. Standard microbial swabbing and plating techniques are limited in that they require hours or even days of incubation to generate results, with such steps as enrichment and colony outgrowth resulting in delays that are often incompatible with manufacturing or usage schedules. Rapid in conduct and considered more objective in operation than visual or tactile inspection techniques, swabbing surfaces using ATP-based assessments are relied on as routine, even standard, methods of hygienic assessment alone or in complement with microbial and visual inspection methods. Still, current ATP methods remain indirect methods of total hygiene assessment and have limitations that must be understood and considered if such methods are to be applied judiciously, especially under increasingly strict demands for the verification of hygiene state. Here, we present current methods of ATP-based bioluminescence assays and describe the limitations of such methods when applied to general food manufacturing or health care facilities.
An empirical study on e-learning uptake by teaching staff at Makerere University Business School

Introducing practical e-learning pedagogy to the University teaching staff brings new opportunity for teaching and learning. Most teaching staff have not had any chance to use learning management system. This course introduced new pedagogical tools that include online lessons, online assessment and collaborative tools in education (wiki, discussion forum). The junior teaching staffs of Makerere University Business School (MUBS) were trained to use the e-learning tools using Modular Object-oriented Dynamic Learning Management System (MOODLE) as the platform for teaching. It was selected for two reasons: it is open source and available for free download and it has good in-built pedagogical tools. The participants evaluated the e-learning environment as the last activity in the course. The evaluation was done using questionnaires. The results indicate that the staff acquired good e-learning pedagogical skills at the end of the course.
Les vésicules extracellulaires comme vecteurs de macromolécules bioactives : modèle du transporteur ABCC7 (CFTR) et application à la biothérapie de la mucoviscidose

La mucoviscidose est une maladie genetique due a des mutations du gene CFTR (Cystic Fibrosis Transmembrane conductance Regulator), conduisant a un defaut d'adressage de la proteine CFTR a la membrane apicale des cellules epitheliales, ou a un deficit de sa fonction de canal a ions chlorure. Ce travail a consiste a etudier les vesicules extracellulaires (EV), microvesicules (MV) et exosomes (Exo), comme vecteurs de la proteine CFTR et de son ARN messager. La preuve de concept du transfert de materiel biologique d'interet par l'intermediaire d'EV, d'abord apportee sur un modele de cellules animales (CHO), a ete validee en cellules humaines. Les EV ont ete isolees a partir de surnageant de Calu-3, cellules exprimant la proteine CFTR de maniere endogene, et de A549 transduites par le vecteur adenoviral Ad5-GFP-CFTR, surexprimant la proteine de fusion GFP-CFTR. Les cellules cibles choisies, A549 et CF15, etaient deficientes en CFTR. Le transfert s'est revele plus efficace en systeme homologue (A549/A549) qu'en systeme heterologue (A549/CF15). Par ailleurs, l'utilisation d'inhibiteurs metaboliques suggere que les EV ne suivent pas une voie d'internalisation cellulaire unique, mais que plusieurs mecanismes sont mis en jeu, dont l'endocytose clathrine dependante et la macropinocytose. Les deux types d'EV sont capables de retablir la fonction canal associee au CFTR dans les cellules CF15 de facon dose-dependante, mais avec un effet de seuil minimum. L'activite CFTR reste stable pendant 3 jours, et a un niveau encore detectable apres 5 jours. Notre travail demontre l'interet potentiel des MV et Exo comme vecteurs de biotherapie de pathologies genetiques
HUMAN INFLUENCE ON THE WARINESS OF MELANOSUCHUS NIGER AND CAIMAN CROCODILUS IN CUYABENO, ECUADOR

The effect of mark-recapture experiments on the wariness of Caiman crocodilus and Mela- nosuchus niger in two lakes in Amazonian Ecuador was examined. Three experiments were conducted with five, seven, and 10 sampling replicates, respectively. Each sampling replicate consisted of one nocturnal spotlight count around the lake, during which caimans were captured, marked, and released. There were negative correlations between the number of individuals seen in each sampling replicate and sampling replicate sequence in both lakes and both species. In one lake, there was a positive correlation between the percentage of wary caimans and the sequence of sampling replicates. Our findings indicate that observation and capture, even if harmless, affect the spatial distribution and wariness of crocodilian populations.
COMPARISON BETWEEN TWO DIFFERENT TREATMENT MODALITY FOR THE MANAGEMENT OF ORAL SUBMUCOUS FIBROSIS

Oral submucous fibrosis (OSMF) is a potentially malignant disorder that primarily affects any part of the oral cavity and sometimes the pharynx. The disease is chronic, insidious, and progressive in nature. This generalized condition of the mouth eventually becomes a debilitating disease with mucosal rigidity causing discomfort, burning, and limitation of opening of the mouth. People with OSMF carry a high‐ risk for development of oral cancer.We divided 100 patients of confirmed OSMF case into two groups, containing 50 patients each. In group 1 Patients were administered orally tablet colchicine 0.5 mg twice daily. Hyaluronidase 1,500 IU was mixed in 1 ml of lignocaine. 0.5 ml of this solution was injected intralesionally in each buccal mucosa once a week. In group 2-Patients were administered intralesional injection of Hyaluronidase 1,500 IU as in group 1 and 0.5 ml of injection Hydrocortisone acetate 25 mg/ In buccal mucosa once a week alternatively. Patients in both the groups were asked to discontinue all betel nut chewing habits during the entire study period.
Hieskoivun laatu vaneripuuna

Esitetaan Helsingin yliopiston maatalous-metsatieteellisen tiedekunnan luvalla tarkastettavaksi Metsatalon luentosalissa 11, Unioninkatu 40 B, perjantaina 25. huhtikuuta 1997 klo 12.00.
Oh The Places You'll Go: How Renewable Electricity Is Constructed

Widespread adoption and installation of renewable energy is vital to slowing climate change. This early stage research explores the statistical relationships between renewable electricity production and latent cultural dimensions embedded in the World Values Survey. Using principle component analysis, we discovered two latent cultural dimensions based on 51 nations: (1) secular-rational versus traditional values, and (2) survival versus self-expression. Both dimensions have significant inverse linear relationships with renewable electricity generation. Therefore, the data show that societies that hold more secular-rational values and promote selfexpression tend to have more renewable electricity generation. Practically speaking, these findings can help guide industry professionals and policy makers as they engage, design, and implement projects within different societies.
Racial Disparities in Frontline Workers and Housing Crowding During COVID-19: Evidence from Geolocation Data

We document that racial disparities in COVID-19 in New York City stem from patterns of commuting and housing crowding. During the initial wave of the pandemic, we find that out-of-home activity related to commuting is strongly associated with COVID-19 cases at the ZIP Code level and hospitalization at an individual level. After layoffs of essential workers decreased commuting, we find case growth continued through household crowding. A larger share of individuals in crowded housing or commuting to essential work are Black, Hispanic, and lower-income. As a result, structural inequalities, rather than population density, play a role in determining the cross-section of COVID-19 risk exposure in urban areas.
Evoked Potential as a Pain Evaluation Index for Neonatal Procedural Pain

Frequent pain has short- and long-term negative influences on the development of the brain and nerves and cognition, motion, and behavior of neonates. Neonates staying in the Neonatal Intensive Care Unit frequently receive painful procedures many times a day. Heel lance is one of the most frequently performed painful procedures for blood sampling, but the pain of heel lance has been not sufficiently managed for a long time. Due to the lack of the analgesic effect and safety of pharmacological intervention, the pain relief for neonatal heel lance is being searched for in diverse combinations of non-pharmacological interventions. To develop pain relief for the heel lance, the Premature Infant Pain Profile (PIPP) comprised of a mixture of physiological and behavioral indices is frequently used as a pain evaluation index, but several problems of PIPP have been pointed out with regard to neonatal pain evaluation, and pain evaluation using PIPP alone interferes with the development of pain relief for neonatal heel lance. Recently, evoked potentials (EP) after heel lance have been attracting attention as an index of evaluating pain objectively and quantitatively for neonates unable to express pain with words. EP detects more sharply pain stimulation and may enable continuous evaluation of neonatal pain along with growth and development. The development of EP-based pain evaluation promotes the development of pain relief for neonatal heel lance.
When the baby cries at night

We study a market characterized by inflows of buyers who are less elastic because they lack both time and information. Data from Italian pharmacies show that the number of newborns in a city generates, at the monthly frequency, exogenous changes in the number of less elastic buyers (the parents) who consume hygiene products demanded by more experienced and elastic consumers as well. We estimate that the number of newborns has a positive effect on equilibrium prices even if marginal costs are nonincreasing in the relevant range of quantity fluctuations. We exploit legislation that fixes the number of pharmacies that should serve a city as a function of the existing population. Using a Regression Discontinuity design, we find that an increase in competition has a significant and negative effect on the capacity of sellers to extract surplus from less elastic buyers. JEL-Code: D43, D83 L13.
Zero and negative eigenvalues

We show that zero is not an eigenvalue of the conformal Laplacian for generic Riemannian metrics. We also discuss non-compactness for sequences of metrics with growing number of negative eigenvalues of the conformal Laplacian. Mathematics Subject Classi cation (2010). 58J50, 58J37, 58D17, 53A30.
Bidding Dynamics and Deadlines in Online Retail Purchases

In data on online auctions and posted price sales of homogeneous goods, we document three robust patterns: First, bidders in auctions tend to increase their bids over time. Second, there is dispersion in transaction prices. Third, auctions and posted price sales of the same good coexist. We show that these three facts can be parsimoniously rationalized by a dynamic model of buyers with deadlines. Buyers have access to a stochastic stream of second-price auctions, as well as posted-price listings that can be used at any time, and buyers only differ in how soon they need to purchase the good. We characterize the equilibrium bidding dynamics using the tools of equilibrium search theory, and confirm by calibration that they can explain the three motivating observations. JEL Classifications: C73, D44, D83
Adaptation to growing season length in the perennial Arabidopsis lyrata

Adaptation to local environment is important for all organisms to guarantee survival and to maximize reproduction. Populations of the same species may live in environments that differ markedly. Due to differential selection pressures this can lead to population differentiation, which can be studied both at the phenotypic and at the gene level. The growing season cued by long days is typically short in the north, whereas southern populations have long growing seasons and are adapted to short days. Seasonal fluctuations in temperature also differ between northern and southern environments. Daylength and temperature regulate the timing of flowering in plants. Environmental regulation of flowering and its genetic basis has been extensively studied in the annual model species Arabidopsis thaliana. The perennial growth and flowering habit has been studied especially in trees, but studies on herbaceous plant species have been lacking. In this thesis, I have studied adaptation to growing season length in a perennial herbaceous model species Arabidopsis lyrata. Individuals from populations adapted to northern and southern environments in Europe were grown in same conditions in the growth chambers and in the field. Differentiation between the populations was studied by observing their flowering phenotypes and by studying the expression of genes that are candidates for governing the phenotypic differentiation. The main result in the thesis was that adaptation to short growing season in north can be seen as long daylength requirement for flowering and as fast developmental rate. Critical daylength for flowering likely regulates especially the timing of flowering cessation in the end of the growing season. Flowering time of individuals from northern populations also responded more strongly to cold treatment (representing winter) than that of the southern population. The cold requirement for flowering guarantees that the plants only flower after the winter in the spring with suitable conditions. Expression studies indicated that population differentiation in flowering could be at least partly governed by the expression variation in a few candidate genes. The results in this thesis are valuable for instance for understanding perennial species in general, including tree and crop species, and for predicting how plants response to changing climate.