Miracle-dz/UniFAR-FTUs huggingface dataset:
THE EFFECT OF SUCCESSOR CHARACTERISTICS ON SUCCESSION PLANNING

The main objective of this study was to determine the effect of successor characteristics on the succession planning of family companies in Bali. This research was conducted at family companies on the textile and weaving industries in Bali, both small, medium and large scale, with the condition that it has done minimal succession in the second generation. Successor characteristics and succession planning were measured by a qualitative approach using a Likert scale. Then the data were analyzed using Partial Least Square Path Modeling (PLS-PM). The results of the study found that the characteristics of successors had a positive and significant effect on succession planning. It meant that the better the successor’s characteristics, the better succession planning would be. Willingness to take over the management of the family business will strengthen the commitment of all family members. Suggestions for further researchers, this family business research is limited to those engaged in the textile and weaving industry, so it needs to be expanded again for family businesses engaged in other business sectors.
Industrial Clusterization to Improve the Competitiveness of Small and Medium Industries in the City of Palembang

The existence of Small and Medium Industries (SMEs) has received attention from the government, but it is felt that it has not been able to contribute maximally to productive economic activities. Palembang City is one of the many regions in Indonesia that has great potential in the development of SMEs. This research is intended as an effort to strengthen SMEs with an industrial cluster approach, namely by mapping cluster development and formulating SMEs development strategies that have competitive advantages. The study population consisted of SMEs Nusantara practitioners in Palembang, which consisted of 260 unit. The sample of this study will focus on the types of Songket industry, the sampling method using snowball sampling techniques. The analytical method used is Cluster Map to determine business people in the cluster, Diamond Cluster to identify strategic factors and SWOT Analysis. The results of the study show the results of mapping the development strategy of SMEs Nusantara, namely to innovate designs, increase sales promotion, establish cooperation with the local government, and carry out marketing through online media.
Evaluation of Cardiac Troponin I as a Non Invasive Tool for Diagnosis of the Newborns and Infants Below 6 Months with Congenital Heart Diseases

Background Congenital heart diseases accounts for nearly one third of all major congenital anomalies. Different modalities for diagnosis of CHD are available, in spite of that only 73% can be diagnosed before discharge from hospital, while 27% discharged without diagnosis. There is an increasing need for new diagnostic modalities to help early diagnosis and screening of CHD, biomarkers as cardiac troponin I represents an excellent choice. Aim The aim of this study is to find new, easy and noninvasive diagnostic modalities for earlier detection of congenital heart diseases. Patients /Methods The study was case control study. The study involved 50 cases. cases will be divided into 2 main groups: group (1) 25 patients with congenital heart diseases confirmed by echocardiography, group (2) (control) 25 healthy newborns and infants, patients with CHD in group (1) was further divided into 2 subgroups: group (1a) patients with simple shunts, group (1b) patients with combined defects. Each case was subjected to complete history, physical examination, and peripheral blood samples were withdrawn and cardiac troponin I level was measured. Results Serum level of cardiac troponin I (cTnI) was higher in the diseased group compared to the control group, and is higher in patients with complex defects compared to patients with simple shunts. The sensitivity of the test was 72% and the specificity was 92%. Conclusion Serum cTnI level was found to have a statistically significant association with congenital heart disease, being higher in complex defects than simple shunts.
A quantitative analysis of housing and its correlates in rural Vietnam

Article history: Received: March 12, 2020 Received in revised format: March 27 2020 Accepted: March 29, 2020 Available online: April 3, 2020 Using data from the 2018 Vietnam Household Living Standard Survey, the current study examines factors associated with housing conditions in rural Vietnam. We used both descriptive statistics and regression analyses. Controlling for other factors in the regression models, the study finds that households with better education and occupation were more likely to have larger sizes of housing area per person, higher value of the house and permanent houses. Also, the housing conditions are much better for the Kinh population (the ethnic majority) than that for ethnic minorities. In addition, we find that the opportunities for obtaining better housing outcomes vary largely across regions. Our research findings suggest that improving the access of ethnic minorities to education and better job are expected to improve the housing conditions. © 2020 by the authors; licensee Growing Science, Canada
High Throughput Approaches to Unravel the Mechanism of Action of a New Vanadium-Based Compound against Trypanosoma cruzi

Treatment for Chagas disease, a parasitosis caused by Trypanosoma cruzi, has always been based on two drugs, nifurtimox and benznidazole, despite the toxic side effects described after prolonged prescription. In this work, we study a new prospective antitrypanosomal drug based on vanadium, here named VIVO(5Brsal)(aminophen). We found a good IC50 value, (3.76 ± 0.08) μM, on CL Brener epimastigotes. The analysis of cell death mechanism allowed us to rule out the implication of a mechanism based on early apoptosis or necrosis. Recovery assays revealed a trypanostatic effect, accompanied by cell shape and motility alterations. An uptake mostly associated with the insoluble fraction of the parasites was deduced through vanadium determinations. Concordantly, no drastic changes of the parasite transcriptome were detected after 6 h of treatment. Instead, proteomic analysis uncovered the modulation of proteins involved in different processes such as energy and redox metabolism, transport systems, detoxifying pathways, ribosomal protein synthesis, and proteasome protein degradation. Overall, the results here presented lead us to propose that VIVO(5Brsal)(aminophen) exerts a trypanostatic effect on T. cruzi affecting parasite insoluble proteins.
CYSTIC PROLACTINOMA: A SURGICAL DISEASE?

Objective Since the advent of dopamine agonists, prolactinomas have been primarily treated medically. However, studies show conflicting data on whether these agents are as effective as surgery for predominantly cystic prolactinomas. We present a case of a patient with a cystic prolactinoma for which surgery was selected as first-line therapy. Methods Literature review. Results A 26-year-old African American man presented to an outside hospital with complaints of dull right-sided headaches for 1 week. The headache worsened over the next few days, which prompted him to go to the emergency room. The evaluation included a head computed tomography, which demonstrated a 4-cm solid/cystic pituitary mass with possible hemorrhagic conversion and compression of the optic chiasm. He was transferred to University of Maryland Medical Center for neurosurgical evaluation. He denied symptoms of pituitary hormone excess or deficiency. He denied visual symptoms, though formal visual field testing demonstrated temporal hemianopia. Hormonal evaluation revealed hyperprolactinemia (prolactin, 1,627 ng/mL) and central hypothyroidism (thyroid-stimulating hormone, 2.72 μIU/mL; free thyroxine, 0.5 ng/dL). Because of the large cystic component of the prolactinoma and clinical evidence for compression of the optic chiasm, the patient underwent transsphenoidal resection of the mass. Postoperatively, the patient was started on bromocriptine for suppression of residual prolactinoma tissue. Notably, the patient developed several complications postoperatively, including diabetes insipidus and secondary hypogonadism. Conclusion Initial management strategies for cystic prolactinomas have been debated. This case highlights the importance of careful consideration of both medical and surgical treatment options in patients with prolactinomas with large cystic components.
Press-Fit Condylar Design Total Knee Arthroplasty

Background: The Press-Fit Condylar total knee arthroplasty implant design has been used by many orthopaedic surgeons over the last twenty years. The design has survived with relatively minor modifications and remains a popular implant system today. The present study represents the fourteen to seventeen-year results for our patients who were described in our previous report on the eight to ten-year results.
Anterior Cervical Fixation

Background: Anterior plates provide stability following decompression and fusion of the cervical spine. Various plate designs have emerged, and they include static plates with fixed-angle screws, rotationally dynamic plates that allow the screws to toggle in the plate, and translationally dynamic plates that allow the screws to both toggle and translate vertically. The goal of this study was to document the effects of plate design following a single-level corpectomy and placement of a full-length strut graft and the effects following 10% subsidence of the graft.
Health-Related Quality of Life in Total Hip and Total Knee Arthroplasty

Background: Total hip and total knee arthroplasties are well accepted as reliable and suitable surgical procedures to return patients to function. Health-related quality-of-life instruments have been used to document outcomes in order to optimize the allocation of resources. The objective of this study was to review the literature regarding the outcomes of total hip and knee arthroplasties as evaluated by health-related quality-of-life instruments.
Current Concepts Review - Displaced Intra-Articular Fractures of the Calcaneus*

Most calcaneal fractures occur in male industrial workers, making the economic importance of this injury substantial. Many authors have reported that patients may be totally incapacitated for as long as three years and partially impaired for as long as five years after the injury. Although modern operative intervention has improved the outcome in many patients, there still is no real consensus on classification, treatment, operative technique, or postoperative management. In this article, the current thinking regarding the treatment of these very difficult fractures will be reviewed.
Treatment of Unicameral Bone Cyst

specific bomse insvolved. The purpose of the present study was to deternsine the behuavior of umsicanseral bomse cysts ins differenut locationus and! to seek answers to suds tiuestionis as: Is the positions of the cyst ins relations to the epiphsyseal plsute of truly prognostic value in regard! to thse results of surgical treatment? Shsould the responssible surgeons sinsply observe a unsicamiseral bomse cyst hoping to protect au active amid normal child fromus imsevitable fracture? Is the recurremice rate after surgical treatnuent prohibitive or do thse conusphications of watchful waitiisg become signsificanst as growths progresses? After reviewing our series of docunsensted unicameral bonse cysts, we believe that a nusore aggressive approach to this orthopaedic problemus is indicated.
Gas chromatography-mass spectroscopy analysis of bioactive compounds in the whole plant parts of ethanolic extract of Asclepias Curassavica L.

Objective: The present study was carried out to cultivate Asclepias curassavica and explore the phytoconstituents of ethanolic extract of A. curassavica whole part using gas chromatography-mass spectroscopy (GC-MS). This research may be useful for constituent(s)-based pharmacological activity. Materials and Methods: 5 g of powdered plant material was taken in a spotless, level container and soaked in 80 ml of ethanol, and extraction was done by hot extraction method. The glass container with extract was sealed and kept aside for few hours. It was then filtered through Whatman filter paper No.42. Ethanolic extract of A. curassavica was further undertaken for GC-MS analysis. Result: The ethanolic extract of the whole plant of A. curassavica revealed the presence of 49 diverse phytochemical compounds. Several of these phytoconstituents are reported to possess pharmacological potential. Conclusion: A. curassavica L. has been successfully cultivated, authenticated, and used for the identification of its organic chemical components by GC-MS. Pesticide residues may have an adverse effect on the food chain, and the concentration should be within permissible range for safe human consumption of any herbal drug product. A. curassavica has been observed as a tremendous source of many important phytochemicals, especially glycosidal, alkaloids, steroidal, and terpenoidal compounds. There were no pesticidal residues found in the tested plant drug. Therefore, it may be explored for the production of natural medicinal formulations in pharmaceutical drug industries including anticancer drugs, antibacterial, antimicrobial, antiasthmatics, urine acidifiers, and antimicrobial on account of its potential antioxidant activity.
Smoking Cessation Efficacy and Safety of Varenicline, an &agr;4&bgr;2 Nicotinic Receptor Partial Agonist

Background: Varenicline, an &agr;4&bgr;2 nicotinic receptor partial agonist, has the potential to relieve nicotine craving and withdrawal symptoms while reducing the reinforcing effects of nicotine. Phase 3 studies have evaluated the effects of varenicline on inducing smoking cessation and maintaining smoking abstinence. Subjects and Methods: Two identically designed randomized, double-blind, smoking cessation studies recruited smokers of 10 or more cigarettes daily who were motivated to quit. Treatment with varenicline 1 mg twice daily was compared with treatment with bupropion 150 mg twice daily or matching placebo for 12 weeks, followed by a 40-week nontreatment observation period. In a third study that investigated maintenance of abstinence, smokers were treated with 12 weeks of open-label varenicline 1 mg twice daily. Subjects who did not smoke during the last week of treatment were eligible to be randomized to varenicline or placebo for an additional 12 weeks, followed by a 28-week nontreatment observation period. Brief smoking cessation counseling was given at clinic visits or telephone contacts scheduled regularly during the entire duration of the 3 studies. Measurement of carbon monoxide in expired breath was used to verify the subjects' reports of nonsmoking. Results: In the 2 smoking cessation studies, varenicline significantly increased the 4-week continuous abstinence rate during weeks 9 to 12 relative to placebo and bupropion. The continuous abstinence rate during weeks 9 to 52 was also increased compared with placebo and with bupropion (statistically significant in one of the studies). In the maintenance study, smokers who quit after an initial course of open-label varenicline had greater long-term efficacy when they received an additional 12 weeks of varenicline than when they received placebo. In all 3 studies, varenicline was safe and well tolerated, with overall treatment discontinuation rates similar to that of placebo. Nausea was the adverse event that occurred more frequently in subjects receiving varenicline but was mostly mild in intensity. Conclusion: The results of these studies demonstrate a new order of efficacy in medical therapy for smoking cessation. Varenicline proved to be more effective than bupropion in inducing cessation. Furthermore, varenicline prevented relapse in smokers who had progressed toward cessation by quitting for at least 1 week.
he Nature of Multidisciplinary HIV Care in he Ambulatory Setting: A Synthesis of the iterature

L p i N K F The purpose of this article is to provide a critical ppraisal and synthesis of the literature relating to he provision of multidisciplinary HIV care in the mbulatory setting. As more people are living with IV infection, and living longer, the demand for hronic care is great. Knowing what optimal care nd treatment for people living with HIV/AIDS is and ow to provide that care is an ongoing challenge. he literature suggests that the provision of care for IV-infected individuals varies across and within IV/AIDS clinics. This variability in care practices ay influence the health and well-being of patients, nd negatively impact on access to such care by eople with HIV/AIDS. The goal of reviewing the iterature on HIV-ambulatory clinics was to provide description of a typical clinic, its staffing compoents, the care practices carried out at such a clinic and by whom), and some barriers to providing opimal care. The ultimate goal of this review is to stablish what is currently known about the provision f these services so that this information may build n existing knowledge and thereby standards of care or HIV-ambulatory clinics can be developed that ould be implemented on a wide-scale basis.
Factors affecting faculty's intent to use e-learning systems at a university in the Kingdom of Saudi Arabia

E-learning systems provide instructors with a platform to create, deliver, and manage course content electronically. Faculty members’ use of an e-learning system at Saudi universities concerns researchers, academics, and practitioners. Although most Saudi universities have an e-learning system, few faculty members are using an e-learning system. The Saudi Arabia Ministry of Education has seen massive investment toward the educational improvement in e-learning systems through building and maintaining an advanced level of Information Technology infrastructure, improving the utilization and flexibility of Information Technology resources, and enhancing and developing the privacy and security of e-learning systems. While previous research has examined factors affecting the acceptance of elearning, few studies have examined the security of e-learning systems. Previous studies indicate the security of e-learning systems is important for motivating faculty to use elearning systems due to issues of trust. Previous research has also examined the positive impact on users’ attitudes toward using e-learning systems by two factors: perceived ease of use (PEOU) and perceived usefulness (PU). The goal of this study was to examine the relationship between faculty members’ intent to use (ITU) the e-learning system at their university and their demographic characteristics, perceptions toward the existing e-learning system security, PEOU, and PU of the e-learning system in one of largest universities at the Kingdom of Saudi Arabia (KSA), King Faisal University (KFU), using an online survey available in Arabic and English. A sample of 219 faculty members from KFU completed the online survey. Results found faculty members’ ITU the e-learning system at KFU was influenced by their previous teaching experience with an e-learning system, the ability to change the user password in the e-learning system, and the PU of the e-learning system. The FACTORS AFFECTING INTENT TO USE E-LEARNING SYSTEM v study findings encourage researchers to study other factors that may influence faculty members’ ITU the e-learning system. Furthermore, the findings will help Information Technology practitioners, especially e-learning systems’ developers, to design and develop systems that will be more likely accepted and useful by the University faculty members. FACTORS AFFECTING INTENT TO USE E-LEARNING SYSTEM vi Table of
Simultaneous Bilateral, Staged Bilateral, and Unilateral Total Knee Arthroplasty

Background: The rates of perioperative morbidity and mortality are areas of concern associated with simultaneous bilateral total knee replacement. The purpose of this paper was to compare the rates of morbidity and mortality and the clinical outcome in large groups of consecutive patients undergoing simultaneous bilateral total knee replacement, unilateral total knee replacement, or staged bilateral total knee replacement.
Extrinsic Risk Factors for Women Breast Cancer in Gaza Strip, Palestine: Associations and Interactions in a Case-Control Study

Background: Worldwide, breast cancer (BC) is the most frequently diagnosed neoplastic disease in women around menopause that is the leading cause of DALYs, because it causes a significant reduction of these women’s ability to function normally in everyday life. Methods: The present hospital-based case-control study was carried out between January and August 2018 using a structured questionnaire on 105 breast cancer women and 210 controls who are clinically free from breast cancer. Data about the study cases were collected in the oncology day-care clinics of the two main hospitals in Gaza strip “Al-Shifa and European Gaza hospitals”. Univariate logistic regression and multivariate logistic regression analyses were employed to identify the significant factors associated with BC. Results: Multivariate logistic regression analyses with adjustment for all confounders revealed that woman with BMI more than or equal 30 kg/m2 are under risk of getting BC 2.9 times greater than those having BMI less than 29 kg/m2 (AOR = 2.895; 95% CI: 1.305 - 6.423). Analysis of risk according to reaching menopause showed that the estimated AOR was greater among those reached menopause (3.137, 95% CI 1.824 - 5.395) than among those that did not reach menopause. The risk of developing BC in the case of a history of incidence of BC in the family was more than two times higher (AOR = 2.632, 95% CI 1.528 - 4.535) than in case of the history of a free family of BC. Conclusion: In this context, the above-mentioned risk factors must be taken into consideration in BC management processes in the Gaza strip.
Trends in the Management of Open Fractures

One hundred and fifty years ago, mortality was common following open fracture. With the advent of modern therapy, however, the expected outcome has improved dramatically. In the treatment of open fractures, the surgeon’s objectives are to prevent infection, promote fracture-healing, and restore function. All patients presenting with an open fracture require initial stabilization, tetanus prophylaxis, systemic antibiotic therapy, prompt surgical débridement and copious irrigation, fracture stabilization, timely wound closure, thorough rehabilitation, and adequate follow-up. In addition, certain patients may benefit from local antibiotic therapy, open wound management (possibly including vacuum-assisted closure), flap closure, bone-grafting, or other adjunctive therapies. In this review, we analyze the evidence concerning a number of important issues in the management of open fractures, including classification, use of antibiotics, timing of operative intervention, irrigation, fixation, soft-tissue coverage, and adjunctive therapies.
Trends in the Epidemiology of Osteomyelitis

Results: The overall age and sex-adjusted annual incidence of osteomyelitis was 21.8 cases per 100,000 person-years. The annual incidence was higher for men than for women and increased with age (p < 0.001). Rates increased with the calendar year (p < 0.001) from 11.4 cases per 100,000 person-years in the period from 1969 to 1979 to 24.4 per 100,000 person-years in the period from 2000 to 2009. The incidence remained relatively stable among children and young adults but almost tripled among individuals older than sixty years; this was partly driven by a significant increase in diabetes-related osteomyelitis from 2.3 cases per 100,000 person-years in the period from 1969 to 1979 to 7.6 cases per 100,000 person-years in the period from 2000 to 2009 (p < 0.001). Forty-four percent of cases involved Staphylococcus aureus infections.