Miracle-dz/UniFAR-FTUs huggingface dataset:
An analysis of winter rain-on-snow climatology in Svalbard

Rain-on-snow (ROS) events are becoming an increasingly common feature of the wintertime climate Svalbard in the High Arctic due to a warming climate. Changes in the frequency, intensity, and spatial distribution of wintertime ROS events in Svalbard are important to understand and quantify due their wide-ranging impacts on the physical environment as well as on human activity. Due to the sparse nature of ground observations across Svalbard, tools for mapping and long-term monitoring of ROS events over large spatial areas are reliant on remote sensing, snow models and atmospheric reanalyses. However, different methods of identifying and measuring ROS events can often present different interpretations of ROS climatology. This study compares a recently published Synthetic Aperture Radar (SAR) based ROS dataset for Svalbard to ROS derived from two snow models and a reanalysis dataset for 2004–2020. Although the number of ROS events differs across the datasets, all datasets exhibit both similarities and differences in the geographical distribution of ROS across the largest island, Spitsbergen. Southern and western coastal areas experience ROS most frequently during the wintertime, with the early winter (November–December) experiencing overall most events compared to the spring (March–April). Moreover, we find that different temperature thresholds are required to obtain the best spatial agreement of ROS events in the model and reanalysis datasets with ground observations. The reanalysis dataset evaluated against ground observations was superior to the other datasets in terms of accuracy due to the assimilation of ground observations into the dataset. The SAR dataset consistently scored lowest in terms of its overall accuracy due to many more false detections, an issue which is most likely explained by the persistence of moisture in the snowpack following the end of a ROS event. Our study not only highlights some spatial differences in ROS frequency and trends but also how comparisons between different datasets can confirm knowledge about the climatic variations across Svalbard where in-situ observations are sparse.
Getting out front with EDI

Cet article traite du developpement de l'echange de donnees informatise (EDI) sur le marche de l'information. De plus les avantages que les entreprises peuvent tirer de la technologie de l'EDI en utilisant Internet pour leurs transactions sont soulignes. L'EDI sur Internet est compare aux VANs (Value Added Networks) dans cet article
Exploration of the Dynamic Variations of the Characteristic Constituents and the Degradation Products of Catalpol during the Process of Radix Rehmanniae

Radix Rehmanniae (RR), a famous traditional Chinese medicine (TCM) widely employed in nourishing Yin and invigorating the kidney, has three common processing forms in clinical practice, including fresh Radix Rehmanniae (FRR), raw Radix Rehmanniae (RRR), and processed Radix Rehmanniae (PRR). However, until now, there has been less exploration of the dynamic variations in the characteristic constituents and degradation products of catalpol as a representative iridoid glycoside with the highest content in RR during the process from FRR to PRR. In this study, an ultra-performance liquid chromatography coupled with photodiode array detector (UPLC-PDA) method was successfully established for the simultaneous determination of ten characteristic components to explore their dynamic variations in different processed products of RR. Among them, iridoid glycosides, especially catalpol, exhibited a sharp decrease from RRR to PRR. Then, three degradation products of catalpol were detected under simulated processing conditions (100 °C, pH 4.8 acetate buffer solution), which were isolated and identified as jiofuraldehyde, cataldehyde, and norviburtinal, respectively. Cataldehyde was first reported as a new compound. Moreover, the specificity of norviburtinal in self-made PRR samples was discovered and validated, which was further confirmed by testing in commercially available PRR samples. In conclusion, our study revealed the decrease in iridoid glycosides and the production of new degradation substances during the process from FRR to PRR, which is critical for unveiling the processing mechanism of RR.
Mitigating PWM Voltage-Induced Partial Discharge by Electrets

Fast switching speed and high-voltage rating offered by wide bandgap (WBG) power electronic switches enable designs with high-efficiency and high-power density. However, high internal electric fields in the power dense designs and the high-dV/dt pulsewidth-modulated (PWM) voltage stresses generated by WBG devices increase the magnitude and repetition rate of partial discharge (PD) that accelerates dielectric material aging and device failure. Studies have shown that PWM voltage characteristics, including rising slope, falling slope, duty cycle, switching frequency, and voltage polarity affect PD magnitude and repetition rate. Recently, we proposed using electrets to counter electric fields in power electronic systems to mitigate PD. In this study, we report for the first time that electret films can mitigate both PD magnitude and PD repetition rate under PWM voltage stimuli. Electret films and regular dielectric films, identical in shape, size, and thickness, are exposed to a variety of PWM voltage waveform while two types of PDs, surface discharge and cavity discharge, are measured. The results show that both PD magnitude and repetition rate reduces substantially with the use of electrets.
Sports and Weight Control in Children

Pediatric obesity is a global concern with distressing comorbid conditions, including mood disturbance, cardiovascular changes, endocrine imbalance, liver disease, sleep apnea, and orthopedic conditions. The primary treatment of this condition includes physical activity. Participating in organized sports has been shown to reduce weight and the complications of pediatric obesity more effectively than individual exercise.
Distribution and potential bioeffects of atrazine in coastal waters

Estuaries provide critical nursery habitat for many commercially and recreationally important fish and shellfish species. These productive, diverse ecosystems are particularly vulnerable to pollution because they serve as repositories for non–point-source contaminants from upland sources, such as pesticide runoff. Atrazine, among the most widely used pesticides in the United States, has also been one of the most extensively studied. There has not, however, been a specific assessment of atrazine in marine and estuarine ecosystems. This document characterizes the presence and transformation of atrazine in coastal waters, and the effects of atrazine on marine organisms. Review of marine and estuarine monitoring data indicate that atrazine is chronically present in U.S. coastal waters at relatively low concentrations. The concentrations detected have typically been below acute biological effects levels, and below the U.S. EPA proposed water quality criteria for atrazine. While direct risk of atrazine impacts are low, uncertainty remains regarding the effects of long-term low levels of atrazine in mixture with other contaminants. It is recommended that best management practices, such as the use of vegetative buffers and public education about pesticide use, be encouraged in the coastal zone to minimize runoff of atrazine into marine and estuarine waters.
Beneficial Effects of Dietary Flaxseed on Non-Alcoholic Fatty Liver Disease

Non-alcoholic fatty liver disease (NAFLD), a significant cause of chronic liver disease, presents a considerable public health concern. Despite this, there is currently no treatment available. This study aimed to investigate dietary flaxseed in the JCR:LA-corpulent rat strain model of NAFLD. Both obese male and female rats were studied along with their lean counterparts after 12 weeks of ingestion of a control diet, or control diet with flaxseed, or high fat, high sucrose (HFHS), or HFHS plus flaxseed. Obese rats showed higher liver weight and increased levels of cholesterol, triglyceride, and saturated fatty acid, which were further elevated in rats on the HFHS diet. The HFHS diet induced a significant two-fold elevation in the plasma levels of both aspartate aminotransferase and alanine aminotransferase in the obese male and female rats. Including flaxseed in the HFHS diet significantly lowered liver weight, depressed the plasma levels of both enzymes in the obese male rats, and reduced hepatic cholesterol and triglyceride content as well as improving the fatty acid profile. In summary, including flaxseed in the diet of male and female obese rats led to an improved lipid composition in the liver and significantly reduced biomarkers of tissue injury despite consuming a HFHS chow.
Experimental Research on Fatigue Behavior of Reinforced UHPC-NC Composite Beams under Cyclic Loading

Ultra-high-performance concrete (UHPC), a new cement-based material that offers high mechanical strength and good durability, has been widely applied in construction and rehabilitation projects in recent years. An optimum bending system is achieved by positioning the UHPC layer at the bottom tensile zone of the composite beam and placing the normal-strength concrete (NC) layer at the upper compression zone, which is described as the UHPC-NC composite beam. The fatigue behavior of reinforced UHPC-NC composite beams was described in this study, with an emphasis on the effects of UHPC layer thickness and fatigue load level on the fatigue life of the beam, deformation of the interface between UHPC and NC layers, as well as the bending stiffness of the beam. A total of 9 reinforced UHPC-NC composite beams were tested under cyclic loading. The test variables include UHPC layer thicknesses (zero, 200, and 360 mm), reinforcement ratios (1.184% and 1.786%), and the upper load levels (0.39~0.65). The results showed that good bonding had been achieved without delamination between UHPC and NC layers prior to the final fatigue failure of the beam, and the bending stiffness of the composite beam experienced a three-stage reduction under cyclic loading. Furthermore, an equation was proposed to predict the stiffness reduction coefficient of UHPC-NC composite beams under cyclic loading.
Safety and Efficacy of PCSK9 Inhibitors in Patients with Acute Coronary Syndrome Who Underwent Coronary Artery Bypass Grafts: A Comparative Retrospective Analysis

Background. The in-hospital reduction in low-density lipoprotein cholesterol (LDL-C) levels following acute coronary syndrome (ACS) is recommended in the current clinical guidelines. However, the efficacy of proprotein convertase subtilisin–kexin type 9 (PCSK9) inhibitors in those patients undergoing coronary artery bypass graft (CABG) has never been demonstrated. Methods. From January 2022 to July 2023, we retrospectively analyzed 74 ACS patients characterized by higher LDL-C levels than guideline targets and who underwent coronary bypass surgery. In the first period (January 2022–January 2023), the patients increased their statin dosage and/or added Ezetimibe (Group STEZE, 43 patients). At a later time (February 2023–July 2023), the patients received not only statins and Ezetimibe but also Evolocumab 140 mg every 2 weeks starting as early as possible (Group STEVO, 31 patients). After one and three months post-discharge, the patients underwent clinical and laboratory controls with an evaluation of the efficacy lipid measurements and every adverse event. Results. The two groups did not differ in terms of preoperative risk factors and Euroscore II (STEVO: 2.14 ± 0.75 vs. STEZE: 2.05 ± 0.6, p = 0.29). Also, there was no difference between the groups in terms of ACS (ST-, Instable angina, or NSTE) and time of symptoms onset regarding total cholesterol, LDL-C, and HDL-C trends from the preprocedural period to 3-month follow-up, but there was a more significant reduction in LDL-C and total cholesterol in the STEVO group (p = 0.01 and p = 0.04, respectively) and no difference in HDL-C rise (p = 0.12). No deaths were reported. In three STEZE group patients, angina recurrence posed the need for percutaneous re-revascularization. No STEVO patients developed significant adverse events. The statistical difference in these serious events, 7% in STEZE vs. 0% in STEVO, was not significant (p = 0.26). Conclusions. Evolocumab initiated “as soon as possible” in ACS patients submitted to CABG with high-intensity statin therapy and Ezetimibe was well tolerated and resulted in a substantial and significant reduction in LDL-C levels at discharge, 1 month, and 3 months. This result is associated with a reduction but without a statistical difference between groups.
Relationship between Reservoir Properties and Chlorite Rims:A Case Study from Yanchang Formation of South Ordos Basin,North China

The chlorite rims are frequently observed in clastic successions.Their content and occurrence may heavily influence the reservoir properties.By using thin section determination and SEM,BSE,EDX analyses,we studied occurrence,timing,mechanism of generation and contribution to porosity preservation for the samples from Yanchang Formation,South Ordos basin.The results show:(1)There exists a spatial coupling of chlorite development with the brackish water delta front facies depositional environment and the biotite-rich arkosic sandstone;(2)The formation timing of chlorite is not earlier than the initial compaction stage,but not later than the appearance of authigenic quartz;(3)Formation of chlorite rims could change the porosity microenvironment and prevent growth of authigenic quartz on the detrital quartz surface;(4)The intercrystalline pores in chlorite rims are of limited value for petroleum storage,but can somehow contribute to the reservoirs as pathways for acidic fluids circulation;(5)The constructive diagenetic role of chlorite rims is their weakening effect for the overburden stress and restricting effect for the autigenic quartz growth in certain degree.
Diameter Change of Dry Wound REBCO Solenoid Pancake Coil by Winding Tension

Winding stress plays a key role in maintaining the initial position of the winding pack in manufacturing superconducting magnets. In this paper, we study the effect of winding tension on radial dimension change of dry wound solenoid pancake coils(PCs). By comparing experiment and simulation of winding results for 150 turn stainless steel and REBCO dry wound pancake coil, effective radial Young's modulus of winding pack is estimated to be 0.5–1.6 GPa and 0.28–0.39 GPa for stainless steel(SS) and REBCO PC depending on the winding tension. Lower effective Young's modulus than the material stiffness(195 GPa for SS and 169 GPa for REBCO) and the increasing trend of Young's modulus with higher tension may be explained by the compressible characteristics of rough surfaces in contact. After that, we found irreversible radial dimension change of REBCO dry wound PCs, while not for SS one. This phenomenon may be originated from the flattening of the REBCO conductor by winding pressure against the intrinsic height difference of REBCO conductor.
TREM2 Alleviates Subarachnoid Hemorrhage-Induced Brain Injury through Attenuating Neuroinflammation and Programmed Cell Death in Vivo and in Vitro.

BACKGROUND Apoptosis and pyroptosis are two types of programmed cell death related to the neuroinflammatory reaction after subarachnoid hemorrhage (SAH). Research indicates that triggering receptor expressed on myeloid cells 2 (TREM2) can regulate the SAH-induced inflammatory response. However, whether TREM2 regulates programmed cell death (apoptosis and pyroptosis) remains to be clarified. The purpose of the present study was to investigate the effects of TREM2 on cell death in SAH. METHODS SAH was induced in adult male C57BL/6J mice by endovascular perforation. An in-vitro cellular model of SAH was established by treating cocultured BV2 microglia and HT22 neuronal cells with oxyhemoglobin. TREM2 overexpression or knockdown was carried out by intraventricular lentivirus injection at 7 d before SAH induction in mice or lentiviral transfection, respectively. Neurobehavioral tests as well as western blot, reverse transcription-quantitative polymerase chain reaction (RT-qPCR), immunofluorescence, Evans blue (EB) staining, Nissl staining, and flow cytometry assays were performed to investigate the neuroprotective role of TREM2 after SAH. RESULTS After SAH, the TREM2 mRNA and protein levels were elevated in SAH mice, exhibiting a peak at 72 h. TREM2 overexpression improved the SAH-induced neurological deficits in mice, while TREM2 knockdown worsened them. In the brains of mice with TREM2 overexpression, less neuronal death and more neuronal survival were detected at 72 h post SAH. Meanwhile, TREM2 overexpression showed an inhibitory effect on microglial activation, neutrophil infiltration, and the expression of cell death marker proteins. Consistent results were obtained in vitro. CONCLUSIONS Our research indicates the important role of TREM2 on cell death after SAH, suggesting that targeting TREM2 might be an effective approach for treating SAH.
Structural architecture and low‐grade metamorphism of the Mikabu‐Northern Chichibu accretionary wedge, SW Japan

To understand tectono‐metamorphic processes within or close to the brittle–ductile transition of quartz‐rich crustal rocks in an accretionary wedge, an integrated field, petrological, geochronological and Raman spectroscopic study was conducted on the Mikabu‐Northern Chichibu belt in SW Japan. Field mapping in central Shikoku reveals that the Northern Chichibu belt is comprised of a pile of four tectono‐stratigraphic units, referred to as A, B, C and D units. The A unit (dominated by pelagic sedimentary rocks) represents the structurally lowest and youngest accretionary complex that forms a composite unit with the Mikabu ophiolitic suite. The B unit (consisting of chert‐clastic rock sequences) overlies the A unit and is overlain by the C and D units (mudstone‐matrix mélange units). Raman spectroscopy of carbonaceous material constrains the peak temperature of each unit to be ~290°C for the A unit, 270–290°C for the B unit, 230–250°C for the C unit and ~220°C for the D unit. Ductile deformation and pervasive metamorphism are limited to rocks in the Mikabu, A and B units. Alkali pyroxene and sodic amphibole occur in metabasite from the Mikabu, A and B units, and the widespread occurrence of prograde veins containing lawsonite+quartz pseudomorphs after laumontite was newly recognized from the C unit. Phase petrological data constrain the peak pressure of each unit to be ~0.65 GPa for the Mikabu‐A unit (aragonite stable), ~0.45–0.6 GPa for the B unit (jadeite+albite stable in the structurally lower part), and ~0.35 GPa for the C unit (prehnite+lawsonite stable). The peak metamorphic pressure increases towards structurally lower and younger accretionary complexes, but the thickness of the preserved strata is insufficient to account for the inferred pressure range. The structural–metamorphic relations imply thickening of the accretionary wedge by underplating was followed by a significant phase of thinning by both ductile and brittle processes.
Self-administered questionnaires enhance emotion estimation of individuals with autism spectrum disorders in a robotic interview setting

Background Robots offer many unique opportunities for helping individuals with autism spectrum disorders (ASD). Determining the optimal motion of robots when interacting with individuals with ASD is important for achieving more natural human-robot interactions and for exploiting the full potential of robotic interventions. Most prior studies have used supervised machine learning (ML) of user behavioral data to enable robot perception of affective states (i.e., arousal and valence) and engagement. It has previously been suggested that including personal demographic information in the identification of individuals with ASD is important for developing an automated system to perceive individual affective states and engagement. In this study, we hypothesized that assessing self-administered questionnaire data would contribute to the development of an automated estimation of the affective state and engagement when individuals with ASD are interviewed by an Android robot, which will be linked to implementing long-term interventions and maintaining the motivation of participants. Methods Participants sat across a table from an android robot that played the role of the interviewer. Each participant underwent a mock job interview. Twenty-five participants with ASD (males 22, females 3, average chronological age = 22.8, average IQ = 94.04) completed the experiment. We collected multimodal data (i.e., audio, motion, gaze, and self-administered questionnaire data) to train a model to correctly classify the state of individuals with ASD when interviewed by an android robot. We demonstrated the technical feasibility of using ML to enable robot perception of affect and engagement of individuals with ASD based on multimodal data. Results For arousal and engagement, the area under the curve (AUC) values of the model estimates and expert coding were relatively high. Overall, the AUC values of arousal, valence, and engagement were improved by including self-administered questionnaire data in the classification. Discussion These findings support the hypothesis that assessing self-administered questionnaire data contributes to the development of an automated estimation of an individual’s affective state and engagement. Given the efficacy of including self-administered questionnaire data, future studies should confirm the effectiveness of such long-term intervention with a robot to maintain participants’ motivation based on the proposed method of emotion estimation.
The effect of “clinical virtual round” on clinical self-efficacy among midwifery students

BACKGROUND: One of the methods of clinical education is clinical rounds which makes students more skilled in the comprehensive care of patients. since midwifery students are faced with low-risk and high-risk cases of mothers during the perinatal period, Therefore, it is necessary to pay attention to their clinical self-efficacy. The aim of this study was to determine. The effect of “clinical virtual round” on clinical self-efficacy among midwifery students. MATERIALS AND METHODS: The study was experimental with the control group design. The subjects were randomly divided into the intervention (n = 30) and control (n = 30) groups. two groups received clinical virtual round and report back model (respectively). subjects in both groups responded to the 20-item clinical self-efficacy Questionnaire, before and after the intervention. Data were analyzed with paired t-test and t-student by SPSS v 22. RESULTS: The baseline mean ± SD scores for clinical self-efficacy in interventional and control groups were 10.1 ± 1.32, and 10.1 ± 3.05 respectively (P = 0.233). clinical virtual round increased clinical self-efficacy (65.1 ± 1.42) of midwifery students compared with the control group (11.1 ± 1.72) (P = 0.002). CONCLUSION: According to this study’s results, it is recommended that clinical virtual rounds can be increasing clinical self-efficacy among midwifery students.