Miracle-dz/UniFAR-FTUs huggingface dataset:
Hydration of Hybrid Cements at Low Temperatures: A Study on Portland Cement-Blast Furnace Slag—Na2SO4

Replacement of Portland cement with high volumes of blast furnace slag is known to negatively affect the early-age properties of concrete, particularly at low temperatures. In this study, the effectiveness of Na2SO4 on the mechanical properties, hydration kinetics and microstructure development of a commercial CEM III/B (~69% slag) is investigated at 10 and 20 °C. Na2SO4 enhances compressive strength at both 10 and 20 °C, and at both early (1 and 7 days) and later ages (28 and 90 days). QXRD shows an increase in the degree of alite hydration at 1 day with Na2SO4 addition, while the degree of clinker and slag hydration is similar for all the systems from 7 to 90 days. An increase in ettringite content is observed at all ages in the systems with Na2SO4. Microstructure and pore structure shows densification of hydrates and reduction in porosity on addition of Na2SO4.
Household preferences for private versus public subsidies for new heating systems: insights from a multi-country discrete choice experiment

ABSTRACT This paper employs demographically representative discrete choice experiments (DCEs) with owner occupiers in Poland, Sweden, and the United Kingdom (UK) to estimate the effects of subsidies, heating cost savings, installation time (reflecting ‘hassle costs’) and warranty length on owner occupiersʻ propensity to invest in a new heating system. In particular, the paper explores whether owner occupiers value subsidies received from public funding sources differently than subsidies received from private funding sources. The results from estimating mixed logit models suggest that respondents not only value subsidies for new heating systems because they decrease the net price, but they also value receiving a subsidy per se. For participants from Sweden (but not from Poland and the UK), this non-monetary value was found to be higher for subsidies offered by a public than by a private funding source. The results for heating cost savings in the three countries imply implicit discount rates between about 11 and 13%. We further find that respondents in Poland dislike longer installation times, and that respondents in all three countries value longer warranty times.
Effect of T6, RRA and nano chromium carbide content on microstructure and mechanical properties of AA7075-Cr3C2 nanocomposite

Abstract In the present study, AA7075 nanocomposites reinforced with varying weight percentage of Cr3C2 nano particles were successfully synthesized by stir casting technique. The pre-milled powder of Cr3C2 nano particles and aluminum powder was incorporated into molten AA7075 during stir casting for uniform dispersion of nano particles. Thereafter, the nanocomposite samples were aged at T6 and RRA (Retrogression and Reaging). The microstructural characterization examined by SEM and optical microscopy revealed uniform distribution of nano particles up to 1.5 wt. % content, above which the agglomeration occurred. The grain refinement was observed with increase in reinforcement content. The T6 and RRA aging treatment led to reduction in the amount of eutectic phases and grains were further more refined. The combined effect of reinforcement addition and aging, significantly improved the strength and hardness, but deteriorated the ductility. The hardness increased from 110.1 BHN for as cast alloy to 159.3 BHN for T6 treated 1.5 wt. % Cr3C2 nano particles reinforced nanocomposite. Similarly, the maximum value of ultimate tensile strength (308.77 MPa) and impact strength (9.3 J) were obtained for T6 treated 1.5 wt. % Cr3C2 nano particles reinforced nanocomposite. Also, T6 treated nanocomposite showed better strength and hardness whereas RRA treated nanocomposites possessed better ductility.
Exploring the Communication of Social Movements in Primary Education

There is much controversy today about several factors involved in children’s education. The last decade has also seen a significant change in the way classes are imparted, with teachers giving greater visibility to subjects of current importance. One of these subjects is the issue of social movements. The present study aimed to identify possible communication strategies between primary school teachers and children and identify possible pedagogical strategies to explain, treat and discuss social movements in classrooms. To carry out the objectives, we used a Delphi method, and we drew on the experience of experts in several social and educational fields to identify the communication strategies. This interactive technique, comprising different phases and a range of questions, was used with experts in the psychology of education, media studies, primary education, and parents to reach a consensus on how best to approach social conflicts in the classroom and obtain predictions. The implications for primary education are discussed.
A Study on the Genetic Algorithm of Thread's Connection Method for Intarsia Sweater Weaving

Abstract The purpose of this paper is to find an optimal weaving connection method of sweater threads while weaving intarsia sweater by the genetic algorithm. The objective function was devised to minimize labor cost and lessen the amount of thread usage. In order to create the parental pop ulation group in the genetic algorithm, we developed five thread connection methods. Besides, elite chromosome screening methods for the offspring group was selected both to the whole chromosome thread elite and to a color-coded elite thread chromosome. Commonly used diamond pattern in Intarsia sweater manufacturing was applied to the experiments. The experimental results showed that thread system saved the labor and material costs than woven method under the existing software. When weaving Intarsia sweater in the field, we can apply the developed genetic algorithm to improve productivity of weaving con-nection method. Keywords：Genetic Algorithm, Intarsia, Sweater, Yarn Weaving, Color Elite , Heuristic Yarn’s Link, Distance Factor, Yarn Cross-Link Factor
The Physiology of Postharvest Tea (Camellia sinensis) Leaves, According to Metabolic Phenotypes and Gene Expression Analysis

Proper postharvest storage preserves horticultural products, including tea, until they can be processed. However, few studies have focused on the physiology of ripening and senescence during postharvest storage, which affects the flavor and quality of tea. In this study, physiological and biochemical indexes of the leaves of tea cultivar ‘Yinghong 9′ preserved at a low temperature and high relative humidity (15–18 °C and 85–95%, PTL) were compared to those of leaves stored at ambient conditions (24 ± 2 °C and relative humidity of 65% ± 5%, UTL). Water content, chromatism, chlorophyll fluorescence, and key metabolites (caffeine, theanine, and catechins) were analyzed over a period of 24 h, and volatilized compounds were determined after 24 h. In addition, the expression of key biosynthesis genes for catechin, caffeine, theanine, and terpene were quantified. The results showed that water content, chromatism, and chlorophyll fluorescence of preserved leaves were more similar to fresh tea leaves than unpreserved tea leaves. After 24 h, the content of aroma volatiles and caffeine significantly increased, while theanine decreased in both groups. Multiple catechin monomers showed distinct changes within 24 h, and EGCG was significantly higher in preserved tea. The expression levels of CsFAS and CsTSI were consistent with the content of farnesene and theanine, respectively, but TCS1 and TCS2 expression did not correlate with caffeine content. Principal component analysis considered results from multiple indexes and suggested that the freshness of PTL was superior to that of UTL. Taken together, preservation conditions in postharvest storage caused a series of physiological and metabolic variations of tea leaves, which were different from those of unpreserved tea leaves. Comprehensive evaluation showed that the preservation conditions used in this study were effective at maintaining the freshness of tea leaves for 2–6 h. This study illustrates the metabolic changes that occur in postharvest tea leaves, which will provide a foundation for improvements to postharvest practices for tea leaves.
Inflammatory, Mechanical and Infectious Complications Associated with Peripheral Intravenous Catheters in Dogs and Cats: A Risk Factor Analysis

The placement of peripheral intravenous catheters (PIVC) is potentially associated with complications that negatively impact healthcare. Our study investigated factors associated with the occurrence of PIVC-related complications in dogs and cats at a Veterinary Teaching Hospital. The second aim was to determine the prevalence of PIVC bacterial colonization. A total of 76 dogs and 40 cats with PIVCs were evaluated for the occurrence of phlebitis and mechanical complications. The devices were removed when they ceased to be functional or when complications occurred, and the content was submitted for bacterial cultures and antimicrobial susceptibility tests. Both multivariable linear regression models and ROC analysis were employed. Complications were recorded in 46.6% of cases, and 20.7% of catheters yielded a positive culture. Among the isolates, 45% were classified as multi-resistant. In dogs, a ≥36-h indwelling time was associated with an increased risk of complications. Male cats seem more prone to developing complications, while the insertion of PIVCs under sedation may represent a protective factor in this species. In conclusion, PIVC-associated complications were frequently observed, and the high rate of positive culture for PIVCs, together with the presence of multi-resistant isolates, is a cause of concern in a hospital setting.
Parallel Structures in Judges and the Formation of the Book

In addition to the well-known repetitions in the book of Judges, this article maps a number of meaningful cases of repetition in the form of parallel structures in chapters 1, 14–16 and 17–21. This special use of repetition can be regarded as characteristic of the editor who was responsible for the book in its final form. The analysis of this phenomenon helps to provide a better view of the structure of the book as a whole and to explain the function of the double references to the death of Joshua and to the twenty years of Samson as a judge. The specific use of parallel structures at the beginning and end of the book can also be related to theories that attempt to reconstruct the formation of the book and the way in which it is connected to both the preceding book of Joshua and the following book of Samuel.
Data Integration Analysis Indicates That Soil Texture and pH Greatly Influence the Acid Buffering Capacity of Global Surface Soils

Soil acidification is a global environmental issue that decreases soil functions, and it has been significantly accelerated by anthropogenic activities in recent decades. Soils can resist acidification upon receiving acid inputs due to the resistance or/and resilience capacity of soils, which is termed the acid buffering capacity of soils, and it is often indicated by the soil pH buffering capacity (pHBC). An increasing number of studies have been conducted to quantify soil pHBC at various sites, but to date, integration of global data is lacking; therefore, the variations in large-scale soil pHBC and the factors that influence these variations are still unclear. In this study, we collected previously published data on soil pHBC to analyze its variations on a large scale, as well as investigate the underlying factors influencing these variations. The results showed that soil pHBC varied substantially from site to site, with a mean of 51.07 ± 50.11 mmol kg−1 pH−1. Soil texture and pH, separately or collectively, explained a considerable proportion of the total variation of global soil pHBC. It is well-established that a series of processes contribute to the soil acid buffering capacity in different pH ranges, and the global data analyses showed that pH 5.5 could be a key threshold value; different buffering systems may be active at pH > 5.5 and pH < 5.5. Moreover, tropical soils were more acid-sensitive than temperate and subtropical soils, and forest soils had significantly lower soil pHBCs than grassland and cropland soils. This could be attributed in part to the different soil properties, such as soil texture or pH, among the different climatic zones and ecosystems.
Photoresponsive prodrug‐dye nanoassembly for in‐situ monitorable cancer therapy

Abstract Photocleavable prodrugs enable controllable drug delivery to target sites modulated by light irradiation. However, the in vivo utility is usually hindered by their insolubility and inefficient delivery. In this study, we report a simple strategy of co‐assembling boron‐dipyrromethene‐chlorambucil prodrug and near‐infrared dye IR783 to fabricate photoresponsive nanoassemblies, which achieved both high prodrug loading capacity (~99%) and efficient light‐triggered prodrug activation. The incorporated IR783 dye not only stabilized the nanoparticles and contributed tumor targeting as usual, but also exhibited degradation after light irradiation and in‐situ monitoring of nanoparticle dissociation by fluorescent imaging. Systemic administration of the nanoparticles and localized light irradiation at tumor sites enabled monitorable and efficient drug release in vivo. Our results demonstrate that such prodrug‐dye co‐assembled nanomedicine is a promising formulation for photoresponsive drug delivery, which would advance the translation of photoresponsive nanomedicines.
HIV Testing Approaches to Optimize Prevention and Treatment for Key and Priority Populations in Malawi

Abstract Background Despite progress in improving antiretroviral therapy (ART) for people with HIV in Malawi, the burden of HIV infections and HIV treatment outcomes among key populations is suboptimal. Client-centered differentiated service delivery approaches may facilitate addressing HIV prevention and treatment needs of key populations in Malawi. Methods De-identified program data routinely collected as part of the LINKAGES project–Malawi were assembled from October 2017 to September 2019. HIV case finding was compared across different testing modalities for each population. Poisson regression was used to estimate the association between testing modalities and ART initiation. Results Of the 18 397 people included in analyses, 10 627 (58%) were female sex workers (FSWs), 2219 (12%) were men who have sex with men (MSM), and 4970 (27%) were clients of FSWs. HIV case finding varied by modality and population, with index testing and enhanced peer outreach demonstrating high yield despite reaching relatively few individuals. FSWs who tested positive through risk network referral testing were more likely to initiate ART within 30 days compared with those who tested positive through clinic-based testing (adjusted risk ratio [aRR], 1.50; 95% CI, 1.23–1.82). For MSM, index testing (aRR, 1.45; 95% CI, 1.06–2.00) and testing through a drop-in center (aRR, 1.82; 95% CI, 1.19–2.78) were associated with 30-day ART initiation. Conclusions These data suggest that differentiated HIV testing and outreach approaches tailored to the needs of different key populations may facilitate improved ART initiation in Malawi. Achieving 0 new infections by 2030 suggests the need to adapt treatment strategies given individual and structural barriers to treatment for key populations with HIV in high-prevalence settings.
Difference in miRNA Expression in Functioning and Silent Corticotroph Pituitary Adenomas Indicates the Role of miRNA in the Regulation of Corticosteroid Receptors

Corticotroph pituitary adenomas commonly cause Cushing’s disease (CD), but some of them are clinically silent. The reason why they do not cause endocrinological symptoms remains unclear. We used data from small RNA sequencing in adenomas causing CD (n = 28) and silent ones (n = 20) to explore the role of miRNA in hormone secretion and clinical status of the tumors. By comparing miRNA profiles, we identified 19 miRNAs differentially expressed in clinically functioning and silent corticotroph adenomas. The analysis of their putative target genes indicates a role of miRNAs in regulation of the corticosteroid receptors expression. Adenomas causing CD have higher expression of hsa-miR-124-3p and hsa-miR-135-5p and lower expression of their target genes NR3C1 and NR3C2. The role of hsa-miR-124-3p in the regulation of NR3C1 was further validated in vitro using AtT-20/D16v-F2 cells. The cells transfected with miR-124-3p mimics showed lower levels of glucocorticoid receptor expression than control cells while the interaction between miR-124-3p and NR3C1 3′ UTR was confirmed using luciferase reporter assay. The results indicate a relatively small difference in miRNA expression between clinically functioning and silent corticotroph pituitary adenomas. High expression of hsa-miR-124-3p in adenomas causing CD plays a role in the regulation of glucocorticoid receptor level and probably in reducing the effect of negative feedback mediated by corticosteroids.
Factors Associated with Ruptured Ectopic Pregnancy: A 10-Year Review at a District Hospital in Ghana

Background Approximately 1–2% of all pregnancies are ectopic. Despite a decline in ectopic pregnancy-related mortality, there is still a paucity of information on the factors associated with clinical presentation and outcomes in Sub-Saharan Africa which is essential in determining the most appropriate treatment modalities. Methods We performed a ten-year retrospective chart review of cases of ectopic pregnancies managed at the Lekma hospital and assessed them for peculiar risk factors, clinical presentation, and outcomes. Associations between patients' sociodemographic characteristics, clinical presentation, and treatment outcome were evaluated using multiple logistic regression and reported as adjusted odds ratios (AOR). The confidence interval (CI) was set at 95%, and a p value <0.05 were considered significant. Results Over the ten-year period, there were 115 ectopic pregnancies and 14,450 deliveries (7.9/1,000). The mean age ± standard deviation of the 115 patients was 27.61 ± 5.56. More than half of the patients were single (59/115, 51.3%). The majority (71.3%) of the patients presented with a ruptured ectopic pregnancy. After adjusting for covariates, the odds of an ectopic pregnancy presenting as ruptured among single patients was 2.63 times higher than that of married patients (AOR = 3.63, 95% CI: 1.33–9.93, p=0.01). Ectopic pregnancies located in the isthmic region of the tube had a 77% lower odds of presenting as ruptured than those located in the ampullary region (AOR = 0.23, 95% CI: 0.07–0.74, p=0.01). The odds of rupturing were 1.69 times increased for every additional week after the missed period (AOR = 2.69, 95% CI: 1.56–4.64, p < 0.01). No mortalities were reported as a result of an ectopic pregnancy. Conclusion Most of the cases of ectopic pregnancy presented ruptured. Marital status and period of amenorrhoea were significantly associated with rupture.
Accountability and Collaboration for Intergovernmental Performance Management: Communicating Goals through the HUD Grantmaking Process

This paper presents an exploratory case study of a performance-based intergovernmental grant program, U.S. Department of Housing and Urban Development's (HUD) homeless assistance grants to local Continuums of Care (CoC). The goal is to illuminate the mechanisms by which a federal agency may communicate its priority goals to local grant recipients and seek to promote local actions that further those goals. The mixed-methods case study finds that meeting HUD performance targets does not lead to larger awards in the competitive grant process, casting doubt on the strength of incentives provided by the competitive grants. Nevertheless, the grant making process plays an important role in communicating federal priorities. The system performance metrics emphasized in the grant process coupled with targeted technical assistance appear to promote a focus on performance at the local level and play a role in system reform and capacity building.
The Genomics and Population Genomics of the Light Brown Apple Moth, Epiphyas postvittana, an Invasive Tortricid Pest of Horticulture

Simple Summary In this study, we produced a genomic resource for the light brown apple moth, Epiphyas postvittana, to understand the biological basis of adaptation to a high number of hosts (polyphagy) and the invasive nature of this and other lepidopteran pests. The light brown apple moth is an invasive pest of horticultural plants, with over 500 recorded plant hosts. With origins in Australia, the pest has subsequently spread to New Zealand, Hawaii, California and Europe, causing significant economic losses for fruit producers. Comparative genomic analyses with other lepidopteran genomes indicate that a high proportion of the genome is made up of repetitive sequences, with the majority of the known elements being DNA transposable elements and retrotransposons. Twenty gene families show significant expansions, including some likely to have a role in its pest status. Finally, population genomics, investigated by a RAD-tag approach, indicated likely patterns of invasion and admixture, with Californian moths most probably being derived from Australia. Abstract The light brown apple moth, Epiphyas postvittana is an invasive, polyphagous pest of horticultural systems around the world. With origins in Australia, the pest has subsequently spread to New Zealand, Hawaii, California and Europe, where it has been found on over 500 plants, including many horticultural crops. We have produced a genomic resource, to understand the biological basis of the polyphagous and invasive nature of this and other lepidopteran pests. The assembled genome sequence encompassed 598 Mb and has an N50 of 301.17 kb, with a BUSCO completion rate of 97.9%. Epiphyas postvittana has 34% of its assembled genome represented as repetitive sequences, with the majority of the known elements made up of longer DNA transposable elements (14.07 Mb) and retrotransposons (LINE 17.83 Mb). Of the 31,389 predicted genes, 28,714 (91.5%) were assigned to 11,438 orthogroups across the Lepidoptera, of which 945 were specific to E. postvittana. Twenty gene families showed significant expansions in E. postvittana, including some likely to have a role in its pest status, such as cytochrome p450s, glutathione-S-transferases and UDP-glucuronosyltransferases. Finally, using a RAD-tag approach, we investigated the population genomics of this pest, looking at its likely patterns of invasion.