Miracle-dz/UniFAR-FTUs huggingface dataset:
A study on the clinicopathological correlation of psoriasis with extent of expression of Osteopontin in OPD patients

1 Junior Resident, Department of Pathology, Hind Institute of Medical Sciences, Safedabad, Barabanki (U.P.) 2 M.D. Professor & Head of Department of Pathology, Hind Institute of Medical Sciences Safedabad, Barabanki (U.P.) 3 M.D., Associate Professor, Department of Pathology, Hind Institute of Medical Sciences Safedabad, Barabanki (U.P.) 4 M.D., ExProfessor & Head, Department of Skin & V.D (U.P.), Hind Institute of Medical Sciences, Safedabad, Barabanki (U.P.) *Corresponding Author Dr Sunil Kumar Gupta M.D., ExProfessor & Head, Department of Skin & V.D (U.P.), Hind Institute of Medical Sciences, Safedabad, Barabanki (U.P.), India Abstract Objective: To evaluate the clinico-pathological Correlation of Osteopontin in patients of Psoriasis. Methods: A cross-sectional clinical correlation study was done on 53 clinically diagnosed cases of psoriasis. All clinically diagnosed cases of Psoriasis were included after taking proper consent in a signed proforma. Patients were clinically evaluated and a proper history was taken including patient’s age, sex, site, duration, family history, community, Itching, nail involvement, H/O associated endocrine disorder, H/O associated skin disorders. The Psoriasis Area and Severity Index (PASI) score was evaluated on the basis of area coverage and plaque appearance.A detailed study of histopathological features and IHC osteopontin expression was analyzed. Results: About one fourth of patients were 20-30 &>40 years of age (26.4%). More than half of patients were males (69.8%). Lower limb was the most common affected site (75.5%). The duration of disease was 12-24 months in 50.9% patients. Psoriasis vulgaris was the most common clinical diagnosis (26.4%). Induration was among majority of patients (94.3%). PASI score ≥10 was among more than half of patients (60.4%). Parakeratosis and Dermal inflammation were the most common histopathological changes (96.2%). Moderate positivity of Osteopontinin the epidermis which was present among more than half of patients (60.4%) followed by weak (30.2%) and strong positivity (9.4%). In Dermis osteopontin positivity was moderate in (50.9%),followed by weak(39.6%) and strong positivity(9.4%)respectively. Conclusion: Because of varied clinical, histopathological and IHC feature of psoriasis. A definitive diagnosis in doubtful cases can be made by a combination of all the above parameters.
Outcomes of Paediatric Hydrocephalus: Comparative Study between Congenital and Post-Infective Hydrocephalus in Sokoto, Nigeria

Introduction: Hydrocephalus is the commonest neurosurgical disease among paediatrics; its management is very challenging. Ventriculo-peritoneal shunt is still the main treatment modality but its usage however, has high complications rate and which have continued to cause concern. The study aimed to compare the outcomes of paediatric hydrocephalus following ventriculo-peritoneal shunt insertion between children with congenital and postinfective hydrocephalus. Materials And Method: A prospective cross-sectional study of I42 children, (71 were congenital hydrocephalus while 71 were post-infective hydrocephalus) were included in the study. All patients had ventriculo-peritoneal shunt insertion and followed of the patients were done, reviewed, analysed and compared among the two groups. Results: Patients with congenital hydrocephalus have age range between 2 weeks and 12 months with a mean age of 3.1 ± 3.3 months, most of these patients were less than 12 months of age (93%) and male to female ratio of 1.7:1. While patients with post-infective hydrocephalus have age range of 3 12 months with a mean age of 8.0 ± 4.6 months, majority of these patients were less than 12 months of age (67.6%) and male to female ratio of 1:1. The incidence of shunt malfunction and shunt infection is higher among children with post-infective hydrocephalus compared with children with congenital hydrocephalus (malfunction; 18.3% vs 4.3% and infection; 4.2% vs 2.8%). However the difference noted was not statistically significant (malfunction, p = 0.561 vs 0.637; shunt infection, p = 0.623 vs 0.676). Conclusion: The complication rate was higher among patients with post-infective hydrocephalus but was not statistically significant when compared with congenital group
On the Changing Role of the Stratosphere on the Tropospheric Ozone Budget: 1979–2010

We study the evolution of tropospheric ozone over the period 1979–2010 using a chemistry‐climate model employing a stratosphere‐troposphere chemistry scheme. By running with specified dynamics, the key feedback of composition on meteorology is suppressed, isolating the chemical response. By using historical forcings and emissions, interactions between processes are realistically represented. We use the model to assess how the ozone responds over time and to investigate model responses and trends. We find that the chlorofluorocarbon (CFC)‐driven decrease in stratospheric ozone plays a significant role in the tropospheric ozone burden. Over the period 1979–1994, the decline in transport of ozone from the stratosphere, partially offsets an emissions‐driven increase in tropospheric ozone production. From 1994–2010, despite a leveling off in emissions, increased stratosphere‐to‐troposphere transport of ozone drives a small increase in the tropospheric ozone burden. These results have implications for the impact of future stratospheric ozone recovery on air quality and radiative forcing.
Uncertainty Analysis of Embedded Energy and Greenhouse Gas Emissions Using BIM in Early Design Stages

With current efforts to increase energy efficiency and reduce greenhouse gas (GHG) emissions of buildings in the operational phase, the share of embedded energy (EE) and embedded GHG emissions is increasing. In early design stages, chances to influence these factors in a positive way are greatest, but very little and vague information about the future building is available. Therefore, this study introduces a building information modeling (BIM)-based method to analyze the contribution of the main functional parts of buildings to find embedded energy demand and GHG emission reduction potentials. At the same time, a sensitivity analysis shows the variance in results due to the uncertainties inherent in early design to avoid misleadingly precise results. The sensitivity analysis provides guidance to the design team as to where to strategically reduce uncertainties in order to increase precision of the overall results. A case study shows that the variability and sensitivity of the results differ between environmental indicators and construction types (wood or concrete). The case study contribution analysis reveals that the building’s structure is the main contributor of roughly half of total GHG emissions if the main structural material is reinforced concrete. Exchanging reinforced concrete for a wood structure reduces total GHG emissions by 25%, with GHG emissions of the structure contributing 33% and windows 30%. Variability can be reduced systematically by first reducing vagueness in geometrical and technical specifications and subsequently in the amount of interior walls. The study shows how a simplified and fast BIM-based calculation provides valuable guidance in early design stages.
COVID-19 infection induces readily detectable morphological and inflammation-related phenotypic changes in peripheral blood monocytes, the severity of which correlate with patient outcome

Background: Excessive monocyte/macrophage activation with the development of a cytokine storm and subsequent acute lung injury, leading to acute respiratory distress syndrome (ARDS) is a feared consequence of infection with COVID-19. The ability to recognize and potentially intervene early in those patients at greatest risk of developing this complication could be of great clinical utility. Methods: We performed detailed flow cytometric analysis of peripheral blood samples from 28 COVID-19 patients treated at Xian No.8 Hospital and the First Affiliated Hospital of Xian Jiaotong University in early 2020 in an attempt to identify factors that could help predict severity of disease and patient outcome. Findings: While we did not detect significant differences in the number of monocytes between patients with COVID-19 and normal healthy individuals,we did identify significant morphological and functional differences, which are more pronounced in patients requiring prolonged hospitalization and ICU admission. Patients with COVID-19 have larger than normal monocytes, easily identified on forward scatter, side scatter analysis by routine flow cytometry,with the presence of a distinct population of monocytes with high forward scatter (FSC-high). On more detailed analysis, these FSC-high monocytes are CD11b+, CD14+, CD16+, CD68+, CD80+, CD163+, CD206+ and secrete IL-6, IL-10 and TNF-alpha, consistent with an inflammatory phenotype. Conclusions: The detection and serial monitoring of this subset of inflammatory monocytes using flow cytometry could be of great help in guiding the prognostication and treatment of patients with COVID-19 and merits further evaluation.
Countering bias? The EU Commission’s consultation with interest groups

ABSTRACT The EU Commission regularly consults with external actors when preparing policy proposals. This paper investigates possible bias in the voices the Commission listens to across all policy areas and consultation instruments. We map the full range of consultation instruments used by the Commission and analyse variation in group representation across types of consultations and policy areas. Our analysis draws on a dataset of more than 350 major Commission proposals between 2011 and 2016. We find that the Commission has established a consultation regime with the widespread use of standard consultation instruments, including open online consultations, stakeholder conferences and consultation in closed fora. The range of consulted actors depends on both consultation instruments and policy types. Open online-consultations are most inclusive. Our findings indicate that the Commission may be able to counteract the influence of business by selecting the most appropriate format for consultation.
Sperm Proteomics Analysis of Diabetic Induced Male Rats as Influenced by Ficus carica Leaf Extract

Diabetes mellitus is shown to bring negative effects on male reproductive health due to long-term effects of insulin deficiency or resistance and increased oxidative stress. Ficus carica (FC), an herbal plant, known to have high antioxidant activity and antidiabetic properties, has been used traditionally to treat diabetes. The objective of this study is to determine the potential of the FC leaf extract in improving sperm quality of streptozotocin (STZ) induced diabetic male rats from proteomics perspective. A total of 20 male rats were divided into four groups; normal (nondiabetic rats), negative control (diabetic rats without treatment), positive control (diabetic rats treated with 300 mg/kg metformin), and FC group (diabetic rats treated with 400 mg/kg FC extract). The treatments were given via oral gavage for 21 consecutive days. The fasting blood glucose (FBG) level of FC treated group demonstrated a significant (p < 0.05) decrease compared to negative group after 21 days of treatment, as well as a significant (p < 0.05) increase in the sperm quality parameters compared to negative group. Sperm proteomics analysis on FC treated group also exhibited the increase of total protein expression especially the proteins related to fertility compared to negative group. In conclusion, this study clearly justified that FC extract has good potential as antihyperglycemic and profertility agent that may be beneficial for male diabetic patients who have fertility problems.
Relationship Between Ethical Leadership Behavior and Work Motivation in Intensive Care Nurses: A Cross-sectional Study

Aim: Affecting the attitudes and the behaviors of the employees, leaders’ ethical focused behavior is one of the most important factors affecting employee work motivation. The study was conducted with the aim of examining the relationship between ethical leadership behavior and the work motivation of Intensive Care Nurses (ICNs). Material and Methods: The study adopted a cross-sectional and descriptive design and was performed between August and October 2018 with 98 ICNs at a university hospital in Turkey. A Nurses’ Description Form, the Ethical Leadership Scale, and the Nurses’ Work Motivation Scale were used to collect data. Since the data were found to be normally distributed, to compare the total scores of ethical leadership scale and nurses’ work motivation scale for demographic information of the nurses independent t-test and analysis of variance (ANOVA) test were used. Pearson correlation analysis was used to determine the relationship between ethical leadership and work satisfaction. Results: A statistically significant positive correlation was found between the mean total score of the Ethical Leadership Scale and the mean total score of the Nurses’ Work Motivation Scale (p < 0.001). A statistically significant difference was found between the mean total score of the ELS and the number of patients for whom daily nursing care was provided (p < 0.05). Conclusions: It was concluded from this study that the perceptions of ICNs concerning ethical leadership behavior and their work motivation were at a medium level. In addition, it was found that the nurses’ ethical leadership behavior had a positive effect on their work motivation. Nursing leaders should therefore endeavor to maintain their ethical behavioral integrity in order to promote nurses’ work motivation.
PARENT’S PERCEPTION TOWARDS EXCESSIVE USE OF TECHNOLOGY AT EARLY PRIMARY (5-7Y) LEVEL

The impact of technology in modern life is multifarious. We use technology in different ways and often times the way we implement various technologies ends up harming our lives or the society we leave in. This study revealed the understanding of the parents about the influence of technology on the child’s social, language and physical health development. the present study conducted by Two Focus Group Discussions (FGD) and four In-depth interviews (IDI) were the basis of the qualitative approach. All the participants were selected through convenient sampling. The findings revealed that children have access to all the technology that is available at home. It was found from the study that children’s screen time was varying from 2 to 5 hours. Findings say that children use technology for entertainment purpose, though educational purpose through Khan Academy also surfaced during the interviews. Another interesting finding was, though video games have adverse effects on children, one cannot bar children from using technology in this modern age. Some parents believe technology has some negative effects. Addiction to digital media is one of the negative effects. Among the other responses, parents identified less physical movement, less social interaction, and obesity of children as the negative influences of excessive technology use. In case of parents’ understanding on usefulness of technology at early primary level, it was found that, children start using smart phones at early age. The parents responded this early literacy of smart phones helped to develop sense of language. From the findings, it can be concluded that, parents do not have the idea of excessive time limit for using technology of their children. Parents should follow some strict parental guidance in case of excessive technology use, find innovative ideas in case of indoor play, take children for outdoor play for physical fitness, give limited playtime for video games with parental guidance. This study will help parents to think about excessive use of technology and balance it with their existing lifestyle. It will help build a social awareness among parents, policy makers and teachers about the excessive limit of using technology.
Calisthenics and bodyweight exercises: different concepts or scientific synonyms?

Bodyweight exercises (also popularly known as calisthenics) is a classic training method and its practice has been widespread since the 19th century, but little evidenced in the scientific literature over the years. This type of training aims to promote multi-system adaptations using body weight as an overload with no or few implements [1–3]. This characteristic makes exercise with body weight easy to apply, in addition to having an excellent cost-benefit ratio when compared to other training possibilities that require machines or materials [4,5].
Accounting Practices and Organizational Performance: Evidence from Small and Medium Scale Enterprises in Sri Lanka

Over the past few decades, the researchers demonstrate consistent effort in investigating the Small and Medium scale Enterprises (SMEs). This sector plays a crucial role in the economic growth in both developing and developed countries. The research investigated how accounting practices influence the organizational performance of small and medium scale enterprises in Sri Lanka. Accounting practices consists of record keeping, budgeting practices and payroll accounting whereas organizational performance is measured by organizational goal achievement, organizational effectiveness and organizational efficiency records. A structured questionnaire was used to collect the primary data from 75 SMEs which were selected by means of the random sampling technique. The results revealed that among the accounting practices, only record keeping and budgeting practices have significant positive influence on organizational performance of Small and medium enterprises in Sri Lanka. It can be recommended that academic institutions and other bodies which are responsible for SMEs should organize training programmes for those operators who do not have the technical knowhow in the field of accounting to come to grips with it and also provide some SME-specific accounting guidelines and template forms for capturing accounting practices for the operators to use. JEL Classification: M41.
A cross sectional study of neutrophil to lymphocyte ratio in patients with benign paroxysmal positional vertigo

Background: Benign paroxysmal position vertigo (BPPV) is a disorder which arises due to problem in inner ear. It is the most common cause of vertigo. Aim: This study evaluates the hs CRP, ESR, NLR, PLR, MHR and bilirubin levels in BPPV patients and compare with levels in healthy subjects. Materials and Methods: This study is a prospective study which was conducted with 120 newly diagnosed BPPV patients and in 90 patients, age and sex matched. Results: The patients were aged between 15 and 75 years. Females were higher than males in both the groups. Smoking rate was higher in-patient group when compared to the control group. Significant lower levels were observed in BPPV patients for vitamin B12, haematocrit, creatinine, urea, fT4, lymphocyte, total, direct, indirect bilirubin levels. HDL, SGOT, ESR values were significantly higher in BPPV patients. Mean neutrophil to lymphocyte ratio (NLR) and platelet to lymphocyte ratio (PLR), MPV values were higher significantly in BPPV patients when compared to healthy control patients. Neutrophil, platelet, monocyte, MHR, CRP were almost similar in both the groups. Conclusion: The potential biomarkers of BPPV were neutrophil to lymphocyte ratio (NLR) and platelet to lymphocyte ratio (PLR), MPV, erythrocyte sedimentation rate (ESR) and bilirubin levels. The NLR levels were significantly higher in BPPV patients.
A Review of Personality in Human-Robot Interactions

A Review of Personality in Human-Robot Interactions reviews the literature on personality and embodied physical action (EPA) robots. This monograph investigates the current state of human-robot personality research, discusses the unique role of personality in human-robot research, and offers guidance for future research. A Review of Personality in Human-Robot Interactions offers several contributions to the literature. First, it presents a conceptual integrated model of the literature on personality in human-robot literature. Second, it highlights four thrust areas in the literature. These areas include: (1) Human Personality and HRI, (2) Robot Personality and HRI, (3) Robot Personality and HRI, and (4) Factors Impacting Robot Personality. Third, it derives and presents major insights from the literature. Finally, it identifies gaps in the literature that need to be addressed. After the introduction, Section 2 presents the relevant literature including the inclusion and exclusion criteria for articles. Section 3 presents and discusses Thrust Area 1: Human Personality and HRI. In sections 4, 5, and 6, a similar discussion takes place for Thrust Area 2: Robot Personality and HRI, Thrust Area 3: Robot Personality and HRI, and Thrust Area 4: Factors Impacting Robot Personality, respectively. Section 7 follows with a discussion on the way forward, focusing on the opportunities for personality research in human‒robot interaction.
Decomposing Factor Momentum

Factor momentum returns do not stem from momentum in factor returns. To study the source of returns, this paper decomposes the stock factor momentum portfolio into a factor timing portfolio and a static portfolio, where the former dynamically collects the return due to serial correlations of factor returns and the latter is designed to collect factor premiums. Sequential sorts of 210 factors show that the static portfolio robustly accounts for a dominant fraction of the total factor momentum return and outperforms in risk-adjusted returns, whereas factor return predictability is empirically too weak to produce significant timing benefits. The static portfolio survives the post-publication decay of factor returns but the factor momentum portfolio does not.
Contribution of Different Elements of Inclined Trash Racks to Head Losses Modeling

Low bar spacing trash racks have been widely investigated in order to guide fish toward bypasses. In addition to this biological function, the formulae to predict head losses, for hydropower plants, are still being discussed. This paper investigates and models the global head losses generated by inclined trash racks with six different bar shapes and two different supports, in an open channel for six angles and two low bar spacings. The girders that supported the trash racks were U-shaped and different profile shapes. In addition to the previously studied rectangular and “hydrodynamic” bars, four new bar shapes, combining different leading and trailing edges, were investigated. Water depths were measured upstream and downstream of the rack for each configuration, and head loss coefficients were characterized and modeled. Three of these new bar shapes generated lower head losses than the hydrodynamic bar shape. The most efficient bar profile reduced the shape coefficient by 40% compared to the hydrodynamic profile and by 67% compared to the conventional rectangular profile. Concerning the supports, the use of a profiled girder to replace a conventional U-shaped girder also significantly reduced the head losses. The addition of the girder effect in a global formula increased its accuracy in predicting head losses of inclined trash racks upstream of hydropower plants.
Estudio fenológico de las comunidades de "Macromycetes" que se desarrollan en los encinares de la provincia de Granada

Se estudia el fenomeno de la "fructificacion" en los hongos superiores que se desarrollan en los encinares de la provincia de Granada (Andalucia, Espana) durante dos anos. Se realiza un apunte geografico, climatico, edafico y floristico de cada una de las zonas estudiadas. Finalmente, se analizan (cualitativa y cuantitativamente) los factores que mas influencia tienen en dicho fenomeno, para despues estudiar el aspecto que presenta la comunidad fungica a lo largo del ano.