Miracle-dz/UniFAR-FTUs huggingface dataset:
Using VDMS to Index and Search 100M Images

Data scientists spend most of their time dealing with data preparation, rather than doing what they know best: build machine learning models and algorithms to solve previously unsolvable problems. In this paper, we describe the Visual Data Management System (VDMS), and demonstrate how it can be used to simplify the data preparation process and consequently gain in efficiency simply because we are using a system designed for the job. To demonstrate this, we use one of the largest available public datasets (YFCC100M), with 100 million images and videos, plus additional data including machine-generated tags, for a total of about ∼ 12TB of data. VDMS differs from existing data management systems due to its focus on supporting machine learning and data analytics pipelines that rely on images, videos, and feature vectors, treating these as first class citizens. We demonstrate how VDMS outperforms well-known and widely used systems for data management by up to ∼ 364x, with an average improvement of about 85x for our use-cases, and particularly at scale, for a image search engine implementation. At the same time, VDMS simplifies the process of data preparation and data access, and provides functionalities non-existent in alternative options.
Diseño y validación de un video educativo para la prevención del VPH

Objetivo: Diseñar y validar un video educativo para la prevención del VPH en jóvenes, mediante el modelo de información, motivación y habilidades conductuales. Metodología: El diseño del presente estudio consistió en seis etapas: 1. - revisión descriptiva de literatura; 2. - análisis de entrevistas con la población blanco; 3. - ubicación de la información obtenida (literatura y entrevistas), en los componentes del modelo de información – motivación - habilidades conductuales (IMH); 4. - elaboración de guión, 5. - proceso de validación de expertos y 6. - prueba piloto.Resultados: Con base en los pasos anteriores, se diseño el video titulado: “¡7 cosas que debes saber sobre el VPH! ”, donde se presentan dos jóvenes (hombre y mujer), que responden de forma clara y sencilla siete preguntas sobre el VPH, finalizando con una serie de recomendaciones para prevenir la infección y promover una sexualidad responsable. La validación se realizó mediante un grupo focal de 10 jóvenes, reunidos en una plataforma en línea y mediante el índice de validez de contenido (IVC), obteniendo un valor de . 92, considerado como bueno y adecuado para comprender los aspectos básicos acerca del VPH.Conclusiones: El diseño y validación de un video para la prevención del VPH es un proceso metodológico hermenéutico y sistemático, que promueve el pensamiento ecléctico, heurístico e innovador para la prevención y promoción de una sexualidad responsable en la población joven. Objective: To design and validate an educational video for the prevention of HPV in young people, using the information, motivation and behavioral skills model.Methodology: The design of the present study consisted of six stages: 1. - descriptive literature review; 2. - analysis of interviews with the target population; 3. - placing the information obtained (literature and interviews) within the components of the information - motivation - behavioral skills model (IMB); 4. - script development, 5. - expert validation process, and 6. - pilot test.Results: Based on the previous steps, the video titled: “7 things you should know about HPV! ” was designed, where two young people (a man and a woman) appear and answer, in a clear and simple way, seven questions about HPV, ending with a series of recommendations to prevent infection and promote responsible sexuality. Validation was carried out using a focus group of 10 young people gathered in an online platform and the content validity index (CVI), obtaining a value of . 92, which is considered good and adequate to understand the basic aspects of HPV.Conclusions: The design and validation of a video for the prevention of HPV is a hermeneutical and systematic methodological process that promotes eclectic, heuristic, and innovative thinking for prevention and promotion of responsible sexuality in the young population.
THE EFFECT OF SELF-REGULATED LEARNING ON STUDENTS’ LIFELONG LEARNING AND CRITICAL THINKING TENDENCIES

Bu arastirmanin temel amaci oz duzenlemeli ogrenmeye dayali ogretim etkinliklerinin, ogrencilerin oz duzenlemeli ogrenme becerilerine, yasam boyu ogrenme ve elestirel dusunme egilimlerine etkisini belirlemektir. Karma yontemin kullanildigi calismanin nicel boyutunda yari deneysel arastirma deseni, nitel boyutunda ise olgubilim deseni kullanilmistir. Arastirmanin calisma grubunu Kirikkale (Turkiye) ilindeki bir ortaokulda ogrenim goren 6. sinif ogrencileri olusturmaktadir. Iki deney ve iki kontrol grubu ile yurutulen calismada her grupta 21 ogrenci olmak uzere, toplam 84 ogrenci yer almistir. Arastirma kapsaminda deney grubuna oz duzenlemeli ogrenme etkinlikleriyle zenginlestirilen ders planlari sekiz hafta boyunca uygulanmis, kontrol grubu ogrencileri ise ders mufredatinda ongorulen yontemlere gore ogretim faaliyetlerini surdurmustur. Nicel verilerin analizinde tek yonlu kovaryans analizi (ANCOVA) kullanilmis, nitel veriler ise icerik analizi yontemiyle cozumlenmistir. Arastirmanin nicel veri analizi sonucunda oz duzenlemeli ogrenmeye dayali uygulama sureci sonunda ogrencilerin oz duzenlemeli ogrenme becerileri, yasam boyu ogrenme ve elestirel dusunme egilimleri uzerinde deney grubu lehine anlamli bir farklilik ortaya cikmistir. Nitel veri analizi sonuclari incelendiginde de, uygulama surecinin ogrencilerin oz duzenlemeli ogrenme becerilerine olumlu katki sagladigi ogrenci gorusleriyle desteklenmistir. Ek olarak bulgular genel olarak ele alindiginda oz duzenlemeli ogrenmenin ogrencilere akademik basari, farkindalik, motivasyon artisi gibi katkilar sagladigi ve bunlarin yani sira ogrencilerin bir kisminin oz duzenlemeli ogrenme stratejilerini diger derslerde de kullanmaya basladigi sonucuna ulasilmistir.
The Physiatry Workforce in 2019 and Beyond, Part 1

Objective The aim of the study was to describe the current physiatrist workforce in the United States. Design An online, cross-sectional survey of board-certified physiatrists in 2019 (N = 616 completed, 30.1% response) collected information about demographic and practice characteristics, including age, sex, practice area, practice setting, hours worked, patient characteristics, staffing, and work responsibilities. Physiatrists were stratified by substantive practice patterns using a cluster analysis approach. Survey responses were arrayed across the practice patterns and differences noted. Results The practice patterns identified included musculoskeletal/pain medicine, general/neurological rehabilitation, academic practice, pediatric rehabilitation, orthopedic/complex conditions rehabilitation, and disability/occupational rehabilitation. Many differences were observed across these practice patterns. Notably, primary practice setting and the extent and ways in which other healthcare staff are used in physiatry practices differed across practice patterns. Physiatrists working in musculoskeletal/pain medicine and disability/occupational rehabilitation were least likely to work with nurse practitioners and physician assistants. Physiatrists working in academic practice, general/neurological rehabilitation, and pediatric rehabilitation were most likely to have primary practice settings in hospitals. Conclusions Physiatry is an evolving medical specialty affected by many of the same trends as other medical specialties. The results of this survey can inform policy discussions and further research on the effects of these trends on physiatrists and physiatry practice in the future.
Age, margin status, high-risk human papillomavirus and cytology independently predict recurrent high-grade cervical intraepithelial neoplasia up to 6 years after treatment

The present study aimed to identify the factors that independently contribute to disease recurrence among women first-time treated for high-grade cervical intraepithelial neoplasia (CIN) during 4–6 years of follow-up. Overall, 529 of 530 eligible patients participated; these patients all attended a 1st follow-up appointment ~6 months post-conization, at which time high-risk human-papillomavirus (HPV) testing, liquid-based cytology and colposcopy were performed. Full data on margin excision status, other aspects of initial treatment and comorbidity were obtained. At least one subsequent follow-up was attended by 88% of patients. A total of 22 recurrent cases were detected during follow-up. Detected recurrence was the outcome of focus for multiple logistic regression analysis, with odds ratios (OR) and 95% confidence intervals (CI) computed. Four significant independent risk factors were identified: Age 45 years or above (OR=3.5, 95% CI=1.3–9.9), one or both unclear or uncertain margins (OR=5.3, 95% CI=2.0–14.2), positive HPV at 1st follow-up (OR=5.8, 95% CI=2.0–16.8), and abnormal cytology at 1st follow-up (OR=3.9, 95% CI=1.4–11.0). Bivariate analysis revealed that persistent HPV positivity was associated with recurrence (P<0.01). These findings indicated that incomplete excision of the CIN lesion may warrant more intensive subsequent screening, regardless of early post-conization HPV findings. Although early post-conization positive HPV was a powerful, independent predictor of recurrent high-grade CIN, over one-third of the patients with detected recurrence had a negative early post-conization HPV finding. These patients returned for routine screening, at which time, in most cases, HPV status was positive, thus indicating the need for repeated HPV evaluation. Especially during the on-going pandemic, home vaginal self-sampling is recommended. Particular attention is required for women aged ≥45 years. In addition, although not statistically significant, relevant comorbidities, especially autoimmune conditions, warrant consideration in clinical decision-making. Women who have been treated for high-grade CIN are at risk for recurrent disease and progression to cervical cancer; therefore, they require careful, individualized follow-up to avoid these adverse consequences.
Progress on microstructure features and creep properties of prospective Tin-Silver-Zinc alloy using a magnetic field

In the current work, applying a rotating magnetic field (RMF) is an innovative approach to improve the microstructure features and creep resistance of Sn-2.0Ag-2.0Zn (SAZ) alloy. The results revealed that RMF does not change intermetallic compounds (IMCs) constituents furthermore SAZ alloy with applying a magnetic field (SAZ-B) exhibited microstructure refinement and homogeneous distribution of IMCs. Moreover, SAZ-B displayed more creep resistance (∼366%) and greater creep rupture time (∼56.4%) than those of SAZ alloy. These results have great implications in improving the alloy’s performance for industrial applications.
Energy Vector and Time Vector in the Dirac Theory

A sign operator of energy, analogous to the helicity operator, but in the direction of what we call energy vector has been introduced. It is possible that there may be physical phenomena where energy vector should be considered. However, to write a wave function this energy vector needs a time vector. But, unlike the energy vector the time vector has no physical meaning yet. To make physical senses of the components of the time vector, the time dilation in special relativity has been studied and also the components of the time vector have been related to the tunneling times when an electron crosses a potential barrier. Physical results for quantum tunneling time will not be limited to this study.
An Empirical Assessment of the Impact of Merger on Lending Behaviour of Deposit Money Banks in Nigeria

This study conducted an empirical assessment of the impact of Merger on lending behaviour of selected Deposit Money Banks in Nigeria from 2006 to 2016 using a panel data collected from the financial statements of the banks over the study period. Multiple Regression is used in the forms of pooled Ordinary Least Square (OLS), Fixed Effect Model (FEM) and Random Effect Model (REM) to analyse the data. Diagnostic tests in the forms of Hausman and Breusch Pagan Lagrange Multiplier Tests were conducted to select the best models. The study used capitalization and volume of deposits as proxies for Merger, while the loans and advances are proxies of lending behaviour. The results from pooled OLS, Fixed and Random Effect models revealed that capitalization and volume of deposits have significant and positive impact on lending behaviour of DMBs in Nigeria. It was also found that there exists difference in the lending behaviour of merged and unmerged banks in Nigeria. The study therefore recommended that capital base of banks should be increase so as to enhance lending activities in the Country. The study also recommended that the saving culture of customers should be encouraged through increased interest rate so that deposit could be mobilized from surplus economic units to deficit economic units in order to increase the volume of deposits. ——————————  ——————————
Templated self-assembly of the bacterial flagellar motor torque ring in vitro

The Bacterial Flagellar Motor is an ion-driven rotary motor employed by many bacteria for motility and surface sensing, and a model system for the self-assembly and regulation of large protein complexes. Early in motor biogenesis a ring of the integral membrane protein FliF templates the cytoplasmic assembly of FliG, which subsequently templates transient incorporation of FliM 1 :FliN 3 subunits. FliG, FliM and FliN collectively comprise the C-ring: site of torque generation and directional switching. Switching is regulated by binding of CheY-P to FliM 1 :FliN 3 , propagating a co-operative conformational change throughout the entire C-ring. The molecular details of C-ring structure, assembly and dynamics are unclear. Averaged cryo-EM structures of purified motors feature a curious symmetry mismatch between the FliF ring (~26-fold) and C-ring (~34-fold), while in vivo fluorescence shows a variation in FliM 1 :FliN 3 population with rotation direction that is not resolved in the EM structures. The stoichiometries of FliG/M/N are all disputed, and cannot yet be measured accurately in vivo . More powerful techniques are available in vitro , but it is unclear whether dynamic structural features of the motor survive purification. Therefore, we aspire to assemble a C-ring in vitro as a platform for in vitro study. Furthermore, by substituting the difficult-to-reconstitute FliF template with a controllable DNA-origami mimic, we envisage studying self-assembly from the bottom up through template remodelling: a novel concept in the study of protein self-assembly. This thesis describes the development of linear DNA templates mimicking short fragments of the FliF ring. FliG arrangement on these templates is specified by DNA sequence design, and can be quantified with single-molecule fluorescence and native gel electrophoresis. The methods developed here will allow testing of the FliG domain-swap polymerization model as a mechanistic explanation for the symmetry mismatch, and lay the foundations for in vitro construction of a complete C-ring.
Morphology Control of Mesoporous Silica Particles Using Bile Acids as Cosurfactants

Morphology control and tuning of nanomaterials are crucial to determine their properties and applications. Solutions based on different synthetic methodologies have been proposed, and in general they required variation of several parameters. Here, a new facile and cost-effective bottom-up strategy to control the morphology of mesoporous silica particles is presented. Specifically, catanionic templating systems composed of bile acids and CTAB enable the production of submicrometer MCM-41 particles of various shapes, high porosity, and remarkable features. The variation of a single component, the bile acid, leads to the preparation of particles with different morphologies. For instance, small (<500 nm) well-separated hexagonal platelets and twisted rods, with tunable aspect ratio and chiral pore channels, were prepared. Experiments aimed at elucidating the role of the bile acids showed that the control of shape is due to the specific interactions between bile acids and CTAB.
Assessing and Explaining Collision Risk in Dynamic Environments for Autonomous Driving Safety

Autonomous vehicles operating in dynamic environments are required to account for other traffic participants. By interpreting sensor information and assessing the collision risk with vehicles, cyclists, and pedestrians, near-misses and accidents can be prevented. Moreover, by explaining risk factors to developers and engineers the overall safety of autonomous driving can be increased in future deployments. In this paper, we have designed, developed, and evaluated an approach for predicting the collision risk with other road users based on a planar 2D collision model. To this end, we have trained interpretable machine learning models to classify and predict the risk of collisions on a range of features extracted from sensor data. Further, we present methods for inferring and explaining the factors mostly contributing to the risk. Using counterfactual inference, our approach allows us to determine the factors which highly influence the risk and should in turn be minimised. Experimental results on real-world driving data show that collision risk can be effectively predicted and explained for different time horizons as well as different types of traffic participants such as cars, cyclists and pedestrians.
Dynamic Market Timing in Mutual Funds

We use the dynamic conditional correlation (DCC) model to estimate daily frequency mutual fund betas. Compared with traditional estimates, daily betas better capture changes in fund risk stemming from daily fund trading activity. Based on these beta estimates and a two-stage estimation procedure, we find significant evidence of market timing ability among actively managed U.S. equity funds that is not apparent via standard approaches. Unlike traditional measures, our timing estimates correlate positively with fund performance. Market timing is especially evident during down markets, with successful timers exhibiting low downside risk. Timing ability persists across time and attracts investor flows. This paper was accepted by David Sraer, finance. Funding: This work was supported by the National Natural Science Foundation of China [Grants 72173127 and 72121001] and by the Institute for Industrial Innovation and Finance at Tsinghua University. Supplemental Material: The data files and online appendix are available at https://doi.org/10.1287/mnsc.2023. 4857 .
YAP1 Protein Expression Has Variant Prognostic Signi�cance in SCLC Strati�ed by Histological Subtypes

Purpose: Yes-associated protein 1 (YAP1), a nuclear effector of an inactivated HIPPO pathway, has been identi�ed as one of four molecular subtypes of SCLC de�ned by the transcriptional regulatory mechanism. We aimed to explore the clinicopathological relevance and prognostic signi�cance of YAP1 expression in SCLC strati�ed by histological subtypes. Methods: Tumor sections and corresponding formalin-�xed para�n-embedded (FFPE) samples of 297 SCLC patients were retrieved from the pathological specimen repository and were subsequently reviewed by pathologists. Forty-six C-SCLCs (15.5%) and 251 P-SCLCs (84.5%) were identi�ed respectively. YAP1 expression was examined by immunohistochemistry (IHC) and assessed semi-quantitatively on tumor tissue array (TMA). Propensity score was used to match C-SCLCs and P-SCLCs in a ratio of 1 to 2 to balance age, gender, tumor stage and treatment methods. Finally, 46 C-SCLCs and 92 P-SCLCs were included for prognostic analysis. Results: The positive rate of YAP1 expression was signi�cantly higher in C-SCLCs than P-SCLCs before matching (52.2% vs 29.1%, P = 0.004). After matching by propensity score, the prescribed clinical parameters were well balanced between P-SCLCs and C-SCLCs. Expression of YAP1 was associated worse overall survival (OS) (5- year OS%, 39.0% vs. 74.9%, P = 0.013) and was an independent risk factor for OS (HR = 2.93, 95% CI: 1.01-8.51; P=0.048) exclusively in C-SCLC. Univariate survival analysis in subgroups of different clinical variables also con�rmed the prognostic impact of YAP1 was most signi�cant in C-SCLC. But for P-SCLCs, expression of YAP1 showed no prognostic impact. Conclusions: Expression of YAP1 in small cell components of C-SCLC was signi�cantly higher than that in P-SCLC. Besides, it served as an unfavorable predictor for OS in C-SCLC but not in P-SCLC, which suggested different entities of small cell components with variant YAP1 expression and potential different targetable oncogenic pathway between C-SCLC and P-SCLC.
Collateral Sensitivity of Resistant Lines of Mouse Leukemias LmOandLSlTSY1

Resistant sublines with pronounced patterns of collateral sensitivity of the mouse leukemias L1210 and LSI78Y were studied. The sensitivity to cytoxan, carbazilquinone, methotrexate, 6-mercaptopurine, and cytosine arabinoside was greatly increased. Median survival times of all lines, except L1210, were shorter when mice were X-irradiated. The growth potential in homologous mice and in hamsters was inversely related to the sensitivity to the chemotherapeutic agents. No uniform pattern in the distribution of chromosome numbers was associated with change in oncogenic potential.
Effects of dietary supplementation with breadfruit leaf powder on growth performance, meat quality, and antioxidative activity in Japanese quail

Background and Aim: In an era of increasing concerns about food availability globally, poultry meat is being increasingly consumed rather than red meat given its quality in terms of pH, color, and tenderness, conferring consumer satisfaction. The choice of feed is a crucial factor in poultry production. This study investigated the effect of dietary supplementation with breadfruit leaf powder on growth performance, meat quality, and antioxidative activity in Japanese quail. Materials and Methods: A total of 120 day-old quail were used in this study and assigned equally into four treatment groups: Group C fed a basal diet and three treatment groups fed a basal diet supplemented with 2.5% (T1), 5% (T2), or 10% (T3) breadfruit leaf powder. The concentrations of breadfruit leaf powder were 2.5, 5, and 10 g/kg in the basal diet. Quail body weight and feed intake (FI) were evaluated at 1, 21, and 35 days of age at 7 a.m. Pectoral muscle was collected to determine pH, meat color, drip loss, cooking loss, water-holding capacity (WHC), tenderness, and antioxidant levels. All variables were analyzed statistically using ANOVA followed by Duncan’s post hoc test (significance set at p<0.05). Results: T3 showed increased body weight gain of quails at1-21 and 21-35 days (p<0.05). Feeding in the T3 group improved the feed conversion ratio compared with those in the C and T1 groups at the starter phase (p<0.05). Dietary treatment did not affect FI (p>0.05). In the present study, meat redness and WHC were improved in the T3 group (p<0.05). Meanwhile, drip loss, cooking loss, and meat tenderness were improved in the T2 group (p<0.05). The pH45 min, pH24 h, lightness, and yellowness were not influenced by the treatments (p>0.05). The antioxidative activities of superoxide dismutase and malondialdehyde decreased in the T3 group (p<0.05), while no significant difference in glutathione peroxidase level (p>0.05) was identified. Conclusion: Ten grams/kilogram of breadfruit leaf powder, as administered in the T3 group, can be applied as a dietary supplement for Japanese quail to improve growth performance, meat quality, and antioxidative activity during the starter and grower periods.