Miracle-dz/UniFAR-FTUs huggingface dataset:
Traffic accident-related injuries in horses

Horses involved in road traffic accidents (RTAs) are commonly presented to veterinarians with varying types of injuries. The aim of this study was describe the pattern and severity of traffic accident-related injuries in horses in a single hospital population. Medical records of horses either hit by a motorized vehicle or involved in RTAs whilst being transported from 1993 to 2015 were retrospectively reviewed and the following data was extracted: Signalement, hospitalisation time, month in which the accident happened, cause of the accident, place of the accident and type of vehicle hitting the horse. Further the different body sites injured (head, neck, breast, fore limb, abdomen, back and spine, pelvis and ileosacral region, hind limb, tail and genital region), the type of injury (wounds, musculoskeletal lesions and internal lesions) and the presence of neurological signs were retrieved from the medical records. 34 horses hit by motorized vehicles and 13 horses involved in RTAs whilst being transported were included in the study. Most of the accidents where horses were hit by motorized vehicles occurred during December (14.7%) and October (14.7%), horses were most commonly hit by cars (85.3%) and the majority of accidents occurred on main roads (26.5%). In 29.4% of the cases, horses had escaped from their paddock and then collided with a motorized vehicle. Most of the accidents with horses involved in RTAs whilst being transported occurred during April (30.8%) and June (23.1%). In 76.9% of the cases the accident happened on a freeway. In the horses hit by motorized vehicles the proximal hind limbs were the body site most commonly affected (44.1%), followed by the proximal front limbs (38.2%) and the head (32.4%). When horses were involved in RTAs whilst being transported the proximal fore limbs (61.5%), the proximal hind limbs (53.8%) and the distal hind limbs, back and head (38.5% each) were the most common injured body sites. Wounds were the most common type of injury in both groups(85.3% hit by motorized vehicle, 76.9% transported ones). In horses hit by a motorized vehicle 35.3% suffered from fractures, in 20.6% a synovial structure was involved and in 5.9% a tendon lesion was present. 14.7% suffered from internal lesions and 14.7% showed neurologic symptoms (40% peripheral, 60% central neurologic deficits). On the other hand, in horses involved in a RTA whilst being transported 30.8% suffered from fractures. There were no synovial structures injured and no tendon injuries were present. Furthermore there were no internal lesions present and only one horse involved in a RTA showed central neurologic symptoms. Injuries of horses being hit by a motorized vehicle were more severe than when horses were protected by a trailer and involved in an RTA whilst being transported. The study has been able to identify the different injury types of traffic accident-related injuries in horses. Awareness of the nature of these injuries is important, to avoid underestimation of their severity.
AG-013736, a multi-target tyrosine kinase receptor inhibitor, demonstrates anti-tumor activity in a Phase 2 study of cytokine-refractory, metastatic renal cell cancer (RCC)

4509 Background: Clear cell renal carcinoma (RCC) is characterized by inactivation of the von Hippel-Lindau tumor suppressor gene, which leads to overexpression of hypoxia-regulated genes including vascular endothelial growth factor (VEGF) and platelet-derived growth factor (PDGF). AG-013736 is an oral small molecule with potent inhibitory effects against the VEGF receptors 1 and 2 and PDGF-β receptor. A phase 2 trial was conducted to assess the safety and efficacy of AG-013736 in cytokine-refractory RCC. Methods: Patients (pts) with metastatic RCC were treated with repeat 4-week cycles of AG-013736 at 5 mg twice daily. Eligibility included measurable disease, ECOG performance status (PS) of 0 or 1 and failure of one prior cytokine-based therapy. A Simon 2 stage minimax design was used (α=0.05; β=0.2; null response rate (RR)=5%; alternative RR=15%). Results: The median age of 52 enrolled pts was 58.5 (35–85) years, 40 (77%) were men, 49 (94%) had prior nephrectomy and 31 (60%) had PS 0. Best response as a.
The Mediating Role of Empathy and Emotion Regulation in Attachment Styles and Dark Personality Traits in Adolescents

Objectives The current study investigated the mediating role of emotion regulation and empathy between attachment styles and dark personality traits. Methods In total, 350 teenage students from Bushehr schools were selected based on convenience sampling method in the academic year of 2017-18. Then, dark traits test, emotional dysregulation, attachment styles, and empathy were distributed among research participants to respond. Collected data were analyzed by correlation indicators and path analysis in LISREL software. Results There was a significant correlation between the components of dark personality traits, empathy, emotional dysregulation, and attachment styles (P<0.05). Moreover, path analysis modeling indicated the mediating role of emotional dysregulation and empathy in the relationship between attachment styles and dark traits (P<0.05). Conclusion The obtained results supported the hypothesis that attachment styles lead to dark traits tendencies and emotional dysregulation. Furthermore, empathy can have a moderating role in this regard.
Changes of Growth, Chlorophyll Content and Solute Composition in Wheat Genotypes Under Salt Stress

Özet: İki buğday türüne ait 6 genotipin (Triticum aestivum L. cv. Bezostaya-1, cv. Seri-82, cv. Kıraç-66 ve Triticum durum Desf. cv. Kızıltan-91, cv. Kunduru 414-44, cv. Ç.1252) tuz stresine tepkileri incelendi. Bitki yetiştirme dolabında 7 gün süreyle büyütülen fideler, 7. günün sonunda Arnon-Hoagland besin çözeltisi içeren kavanozlara alındı. Tuz stresi uygulaması besin çözeltisine 200 mM NaCl eklenmesi ile gerçekleştirildi. Deneme sonunda tuz stresi altındaki bitkilerde bitki büyümesi ve oransal su içeriğinin (OSİ) önemli ölçüde azaldığı tespit edildi. Klorofil a, b ve toplam klorofil içeriği önemli ölçüde azalırken, klorofil a/b oranı çeşitlere göre değişiklik gösterdi. Prolin miktarının tuz stresi altındaki fidelerde çarpıcı bir şekilde arttığı bulundu. Çözünür protein ve çözünür fenolikler hafifçe artış gösterirken, çözünür karbonhidrat miktarı Seri-82 ve Ç-1252 çeşitleri hariç azaldı. Sonuçlar, incelenen genotipler arasında tuzluluğa tepkide önemli farklılıklar olduğunu ortaya koymaktadır.
TEACHING DISABILITY AND REHABILITATION TO UNDERGRADUATE MEDICAL STUDENTS IN TWO UNIVERSITIES IN SOUTH AFRICA

A cross sectional survey was conducted to find out the extent to which undergraduate clinical medical students (N=235) in two universities in South Africa were exposed to structured teaching of disability and rehabilitation. There were multiple opportunities to learn about disability and rehabilitation (n=444), with medical doctors facilitating 40.8%, focusing greater emphasis on disease and impairment. In one of the universities, the survey was followed by a focus group discussion involving 11 students (including 5 persons with disabilities) in the postgraduate Disability Studies program. The focus group reviewed the outcome of the survey and made recommendations on strengthening available learning opportunities for medical students to acquire the knowledge, skills and attitudes required to provide effective service to persons with disability.
The association between medical injections and prevalent HIV infection: Evidence from a national sero-survey in Uganda.

Background. The contribution of unsafe medical injections to HIV transmission in sub-Saharan Africa has been debated. In this study we examine the relationship between the number of medical injections and HIV serostatus among men and women in Uganda. Methods. Data are from the 2004-05 Uganda HIV/AIDS Sero-Behavioural Survey (UHSBS) involving self-report data on medical injections and HIV testing among 8298 men and 10227 women age 15-59. The association between the number of medical injections a respondent received in previous 12 months and HIV serostatus was examined using multivariate logistic regression accounting for possible reverse causation by excluding HIV-positive men and women who reported to be sick for at least 3 months in the previous 12 months and adjusting for several risk factors and potential confounders including self-reported sexually transmitted infections (STIs). Results. Thirty-eight percent of men and 50% of women received at least one injection from a healthcare provider in the previous 12 months. The average number of medical injections per person per year was 1.9 for men and 2.5 for women. HIV prevalence was much higher among men (10.8%) and women (11.4%) who received five or more medical injections in the past year than among those who received no injections (4.0% among men and 6.3% among women). Men and women who received 3-4 injections also had higher HIV prevalence (6.6% among men and 8.3% among women) than those who had no injections. Even after accounting for several risk factors and potential confounders men and women who received five or more injections were significantly more likely to be HIV-positive than those who had no injections (aOR=2.35 95%CI:1.78-3.11 for men; aOR=1.55 95%CI:1.24-1.94 for women). Excluding HIV-infected adults who were chronically ill in the past 12 months reduced the magnitude slightly but the relationship remained significant (aOR=2.25 95%CI:1.68-3.01 for men; aOR=1.47 95%CI:1.17-1.85 for women). Conclusions. Receiving frequent medical injections is associated with significantly higher probability of being HIV infected among Ugandan adults. Medical injection as a potential mode of HIV transmission deserves continued research and programmatic attention.
Hydrogen / Solar-based Boat Propulsion System: Design, Modelling and Implementation on a Scale Model

As climate change becomes a more widely recognized global problem, electrical propulsion of vehicles appears to be a promising solution to cut green house gases emissions. While the automotive industry makes rapid strides towards a mature electric car market, very few initiatives have arisen in the maritime sector thus far. Existing recreational electric boats are often powered either by batteries only, photovoltaic panels and batteries, or fuel cell and batteries, with range and performances dependent upon sun radiation and hydrogen storage capacity. This study contemplates an electric propulsion system for a boat, encompassing battery, photovoltaic panels and a hydrogen fuel cell, which provide incomparable range and flexibility of use. This propulsion system has been designed for a 1/8 scale model (2 m long) of the Hidrocat catamaran in order to reach required speed and to offer suitable range. The elements of the propulsion system have been characterized individually in a laboratory and a simulation model has been created based on this testing campaign. It permits simulation of various sailing schemes as well as study and prediction of energy flows and consumptions. Several trials with the catamaran scale model were conducted while monitoring the circuit components. The experimental data acquired during live testing of the scale model were compared to the output of the simulations and both were consistent which confirmed the reliability of the simulator model. The behaviour of the propulsion system encompassing two renewable sources energy was efficient and the technological choices have been validated.
Corse-to-Fine Road Extraction Based on Local Dirichlet Mixture Models and Multiscale-High-Order Deep Learning

Road extraction from remote sensing images is an attractive but difficult task. Gray-value distribution and structure feature information are both crucial for road extraction task. However, existing methods mainly focus on structure feature information which contains morphological shape features and machine learning features, suffering from lots of false positives which are generated at positions having similar structure features but different gray-value distribution with roads. To effectively fuse the two complementary gray-value distribution and structure feature information, we propose a coarse-to-fine road extraction algorithm from remote sensing images. First, at the coarse level, we introduce a local Dirichlet mixture models (LDMM) which utilizing gray-value distribution information to pre-segment images into potential roads and backgrounds. Thus, most backgrounds having different gray-value distribution with roads can be removed firstly. Compared with original Dirichlet mixture models, the LDMM is much faster and more accurate. Next, at the fine level, we introduce a multiscal-high-order deep learning strategy based on ResNet model which can learn robust structure context features for final road extraction step. Based on the results of LDMM, the multiscal-high-order strategy can further remove false positives which have different structure features with roads. Compared with a single scanning size ResNet, our multiscale-high-order strategy can learn higher-order context information, leading to better performances. We test our algorithm on Shaoshan dataset. Experiments illustrate our better performance compared with other six state-of-the-art methods.
Rhoticity in Brunei and Singapore English

Rhoticity refers to accents in which [r] is pronounced whenever there is an ‘r’ in the spelling. This paper investigates the difference in rhoticity between Brunei and Singapore English. 30 recordings from the Universiti Brunei Darussalam Corpus of Spoken Brunei English (UBDCSBE) and also 30 recordings from the National Institute of Education Corpus of Spoken Singapore English (NIECSSE) were used to analyse potential instances of rhoticity. The speakers are 15 female and 15 male from each variety of English. Over 500 tokens of potential r-colouring were analysed auditorily and acoustically. The study finds that 53% of the Brunei English speakers have rhotic accents, while only 7% of the Singapore English speakers have rhotic accents. However, recent studies suggest that rhoticity is increasing in both Brunei and Singapore.
Therapeutic management of neuro-oncologic patients - potential relevance of CSF liquid biopsy

Background: In the era of precision medicine, cancer treatment is increasingly tailored according to tumor-specific genomic alterations. The analysis of tumor-derived circulating nucleic acids in cerebrospinal fluid (CSF) by next generation sequencing (NGS) may facilitate precision medicine in the field of CNS cancer. We therefore evaluated whether NGS from CSF of neuro-oncologic patients reliably detects tumor-specific genomic alterations and whether this may help to guide the management of patients with CNS cancer in clinical practice. Patient and methods: CSF samples from 27 patients with various primary and secondary CNS malignancies were collected and evaluated by NGS using a targeted, amplicon-based NGS-panel (Oncomine Focus Assay). All cases were discussed within the framework of a molecular tumor board at the Comprehensive Cancer Center Munich. Results: NGS was technically successful in 23/27 patients (85%). Genomic alterations were detectable in 20/27 patients (74%), 11/27 (40%) of which were potentially actionable. After discussion in the MTB, a change of therapeutic management was recommended in 7/27 (26%) of the cases. However, due to rapid clinical progression, only 4/27 (15%) of the patients were treated according to the recommendation. In a subset of patients (6/27, 22%), a high number of mutations of unknown significance suggestive of a high tumor mutational burden (TMB) were detected. Conclusions: NGS from cerebrospinal fluid is feasible in routine clinical practice and yields therapeutically relevant alterations in a large subset of patients. Integration of this approach into a precision cancer medicine program might help to improve therapeutic options for patients with CNS cancer.
Micropropagation of Degenia velebitica (Deg.) Hay., a Croatian Endemic Plant Species

PEVALEK-KOZLINA B. , PAVLICA M. & VUJEVIC M. 1999. Micropropagation oi Degenia velebitica (Deg.) Hay. , a Croatian endemic plant species. Phyton (Horn, Austria) 39 (3): (293) (296). The micropropagation possibility for Degenia velebitica (Deg.) Hay. , a Croatian endemic plant species was investigated. Shoots originated from aseptically germinated seeds collected on natural habitats were used for culture initiation. The highest multiplication rate of Degenia velebitica shoots (5.2 shoots per explant) was achieved on half strength MS medium supplemented with 2.9 \xM gibberellic acid and 0.5 ^M 6-benzylaminopurine (BA). Excised shoots (2-4 cm) were rooted on the same basal medium with addition of 4.9 \xM indole-3-butyric acid (IBA). Rooted plantlets were successfully transferred to potting soil and acclimatized to outdoor conditions.
Production Potential and Economics of Intercropping in Autumn-Planted Sugarcane

In a field experiment, the agro-economic benefits of some autumn sugarcane based intercropping systems were determined at the University of Agriculture, Faisalabad. The intercropping systems comprised sugarcane + sarsoon, sugarcane + sunflower, sugarcane + wheat, sugarcane + gram, sugarcane + lentil, sugarcane + peas, sugarcane + garlic and sole sugarcane. Cane yield was reduced by 21.8, 17.9, 18.0, 11.7, 4.8, 2.6 and 1.4% with intercropping of the respective crops. However, at the cost of this much reduction in cane yield additional harvests of 1702, 2609, 4398, 1719, 526, 1033 and 1645 kg ha of the respective intercrops were obtained which enhanced the net income substantially over pure stand of sugarcane with the maximum of Rs. 1,13,188 ha for sugarcane intercropped with garlic followed by sugarcane + gram (Rs. 96, 207 ha), sugarcane + peas (Rs. 94,399 ha) and sugarcane + sunflower (Rs. 92,622 ha). By contrast sucrose content in cane juice was not affected significantly by different intercrops.
Relationship between pes planus foot type and postural stability

Objective To investigate whether there is a correlation between the degree of pes planus foot deformity and postural stability. Design Prospective correlation study. Setting Sheffield Hallam University, UK Participants Eight healthy volunteers (15 feet) with pes planus foot type. Main Outcomes Measures: Pes planus was defined by the Navicular Drop test (NDT) where a drop >10mm was regarded as pes planus. The SMS Healthcare Balance Performance Monitor (BPM) was used to measure static postural stability using the mean sway number in the lateral and anterior-posterior directions where the higher the sway number the higher the instability. Results In the anteroposterior direction there is a good correlation, (spearman's rank = 0.670) which is statistically significant (p= 0.006) indicating that as the degree of pes planus increases the degree of postural stability decreases. In the lateral direction there is a good to excellent correlation, (spearman's rank = 0.880) which is statistically significant (p= 0.01) indicating that as the degree of pes planus increases the degree of postural stability decreases. Conclusions As the degree of pes planus deformity increases the degree of static postural stability decreases. These findings may have important implications for clinical practice and future research.
Fasting glucose of patients from public health care in the southern region of São Paulo: correlation with glycated hemoglobin and lipid levels

REV BRAS EPIDEMIOL 2019; 22: E190058 ABSTRACT: Introduction: Fasting glucose is a test used for monitoring diabetes mellitus, as well as its screening and diagnosis. The objective of this study was to evaluate fasting glucose results and their correlation with glycated hemoglobin and lipids. Methods: Cross-sectional study, involving 77,581 patients, attended in 2014. Results: The majority of the patients are women (65%). The age of the patients ranged from 18 to 115 years (mean of 53 ± 15.5). The agreement between fasting glucose and glycated hemoglobin was moderate (kappa = 0.416); however, it was substantial for the levels used for the diagnosis of diabetes (kappa = 0.689) and poor for pre-diabetes (kappa = 0.188). Fasting glucose ≥ 100 mg/dL was observed in 41.1% of the patients and 61.5% present glycated hemoglobin ≥ 5.7%. Lipid abnormalities are likeliest in patients with elevated fasting glucose. From those 14,241 individuals that had fasting glucose ≥ 126 mg/dL, the microalbuminuria test was performed in only 883 (6.2%) patients, with abnormal results in 201 (22.8%). Conclusions: The high frequency of fasting glucose with abnormal results may reflect the high proportion of exams performed by individuals with diagnosis of diabetes, to evaluate their glycemic control. The low frequency of requests for microalbuminuria tests in those with probable diagnosis of diabetes reflects the little attention paid for the screening of chronic complications of diabetes. It calls attention the high frequency of dyslipidemia in those individuals, highlighting the fact that this is a population with high cardiovascular risk.
EVALUATION OF THE EFFICACY OF TRANSDERMAL DELIVERY OF CHLOROQUINE ON MALARIA PARASITES IN PLASMODIUM BERGHEI-INFECTED MALE SPRAGUE-DAWLEY RATS: EFFECTS ON BLOOD GLUCOSE AND RENAL ELECTROLYTE HANDLING

viii CHAPTER 1 – Introduction/ Literature review 1.1. Background 1 1.2. The Plasmodium life cycle and pathogenesis 2 1.2.1. Role of hepcidin in anaemia 4 1.3. Management of malaria 5 1.3. 1. Control of malaria transmission 5 1.3. 2. Drug intervention for the management of malaria 6 1.3. 2.1. Artemisinin derivatives 6 1.3. 2.2. Quinine related drugs 7 1.4. Choroquine (CHQ) 8 1.4. 1. Mechanism of action 8 1.4. 2. CHQ absorption, metabolism and excretion 9 1.5. Adverse effects of CHQ or malaria 10 1.5. 1. Effects of malaria on blood glucose homeostasis 11 1.5. 2. Effects of CHQ on blood glucose 11 1.5. 3. Effects of malaria on renal function 12 1.5. 4. Effects of CHQ on renal function 12
Tuning Parameter Selection in the Synthetic Control Method

In this paper I show an asymptotically optimal choice of a weighting matrix used in the synthetic control method. The synthetic control method takes a weighted average of outcomes for untreated units to estimate the outcome under no treatment for a treated unit. This can then be used to estimate a treatment effect for the treated unit. The weights are chosen such that the weighted average of the outcomes in the pretreatment time periods and of covariates approximates that of the treated unit. In practice, these weights are chosen to minimize a distance which depends on a weighting matrix. I show asymptotic optimality of a leave-one-out cross-validation procedure to choose this weighting matrix. This amounts to performing the synthetic control method, in turn, as if each of the untreated units were instead treated and assessing the prediction on the untreated units for a given weighting matrix. This is not straightforward because there is dependence across these synthetic control estimates. ∗Northwestern University, Department of Economics
The Status of Happiness and its Association with Demographic Variables among the Paramedical Students

Background and purpose: In recent years, along with the development of positive psychology, happiness has been the basic pivot of the studies conducted in this area. Due to the importance of happiness in all dimensions of life, the present study aimed at determining the status of happiness among paramedical students. Materials and methods: This descriptive study was conducted on 320 paramedical students who were selected through simple random sampling. The data were collected using Oxford Happiness Inventory. Results: Overall, no significant relationship was found between happiness score and gender (P=0.05). Findings showed that the statements related to self-esteem and satisfaction factors were just significant in relation to the students’ major (P 0.05). Conclusion: Findings of the study showed that happiness of the students depends on their major and level of education, while other variables, namely, age, gender, and marital status had no significant relationship with the happiness.