Miracle-dz/UniFAR-FTUs huggingface dataset:
Biology of Drug-Induced Gingival Hyperplasia: In Vitro Study of the Effect of Nifedipine on Human Fibroblasts

Background: It has been proven that the antihypertensive agent nifedipine can cause gingival overgrowth as a side effect. The aim of this study was to analyze the effects of pharmacological treatment with nifedipine on human gingival fibroblasts activity, investigating the possible pathogenetic mechanisms that lead to the onset of gingival enlargement. Methods: The expression profile of 57 genes belonging to the “Extracellular Matrix and Adhesion Molecules” pathway, fibroblasts’ viability at different drug concentrations, and E-cadherin levels in treated fibroblasts were assessed using real-time Polymerase Chain Reaction, PrestoBlue™ cell viability test, and an enzyme-linked immunoassay (ELISA), respectively. Results: Metalloproteinase 24 and 8 (MMP24, MMP8) showed significant upregulation in treated cells with respect to the control group, and cell adhesion gene CDH1 (E-cadherin) levels were recorded as increased in treated fibroblasts using both real-time PCR and ELISA. Downregulation was observed for transmembrane receptors ITGA6 and ITGB4, the basement membrane constituent LAMA1 and LAMB1, and the extracellular matrix protease MMP11, MMP16, and MMP26. Conclusions: The obtained data suggested that the pathogenesis of nifedipine-induced gingival overgrowth is characterized by an excessive accumulation of collagen due to the inhibition of collagen intracellular and extracellular degradation pathways.
The Influence of Brand Credibility towards Words of Mouth of Fashion Brand

This research tries to examine the factors influencing the positive word of mouth of Indonesian’s consumer towards fashion brand. The factors studied include brand credibility and brand-self connection as independent variables, brand-self connection and brand-social connection as the mediating variables, and memorial brand experience as the moderating variable. This study is quantitative research with data collection method using the electronic questionnaires of Google forms. This study uses 300 respondents of Prada Italian brand in Indonesia and the data is analyzed using structural equation modelling. The results show that brand credibility, brand self-connection, and brand social connection have a positive effect on word of mouth. Both brand self-connection and brand social connection mediate the influence of brand credibility on word of mouth. This study suggests that by preserving the relationships with consumers as well as consumer relationships with other consumers, managers would be able to produce more positive word of mouth.
Effects of Seasonal Freezing-thawing on the Protistan Communities in a Mountain Lake

Background: Freezing-thawing cycles are common phenomena in temperate regions. Such events may have a significant influence on the composition of the protistan communities in a mountain lake. Protists are single-celled eukaryotic microorganisms that act as links in the aquatic microbial food web, affecting the transfer of substances and energy transformation. Yet little is known about the effects of freezing and thawing on the protistan community in a mountain lake. Results: The protistan communities in the lake were mainly composed of Ochrophyta, Ciliophora, Choanoflagellida, Cryptophyta, Chlorophyta, Stramenopiles_X, Cercozoa, Dinophyta, and Haptophyta. Seasonal freezing and thawing affected the community composition and diversity of protists. The change in the protistan community structure resulted from a significant change in organic carbon from the ice-covered to ice-free period. During the ice-covered and ice-free periods, temperature and nitrate were the main causes, respectively, for the changes in protistan community structure at different depths. Water depth also affected the structure of the protistan community, but it was not the most important factor. Conclusions: This study revealed that duration of lake surface icing might affect the function of subalpine lake ecosystems, including the rate of nutrient cycling and energy flow, owing to changes in the structure and biodiversity of the microbial community.
Techno-Creativity: The Implementation of DVFx as Creative Support Tools Among Filmmakers in Malaysia, India & Australia

Previously, the use of digital visual effects (DVFx) only serves merely to fix or modify the damage or harmful elements in the post-production. Still, there are differences between improving the work and the creative effects in work. Subtracting part of the image can often be seen as a form of creativity in generating new image elements. DVFx is also seen as a form of creative effects. It is a fascinating field of study on 'adverse impact' or 'creative impact' in film production. Creative impact in the production process of film is likely to lead to a new assessment on the aspects of 'creativity. ' The occurrence of technological changes that involve creative work will undoubtedly lead to a shift in creativity. Technology and creativity or techno-creativity are likely to represent a new creative possibility and measurement in film production using creative software as a support tool. This paper discusses the findings derived from in-depth interviews conducted with filmmakers, visual effects artists and supervisors from Malaysia, India, and Australia on implementing DVFx as creative support tools. The finding shows that DVFx functions as a techno-creative device in two main areas: ideation and implementation. These two aspects involve using DVFx as a tool for transforming the ideas and the imagination of a filmmaker into a reality on the screen. In other words, DVFx has acted as creative support tools (CST) to increase techno-creativity, especially in the area of visual presentation. Keywords: Creativity, digital visual effects, creative support tools, media technology, globalization.
Role of endoscopic ultrasound-guided liver biopsy: a meta-analysis

Abstract Background Endoscopic ultrasound-guided liver biopsy (EUS-LB) is an evolving technique. In this meta-analysis, we aimed to evaluate the value of EUS-LB for parenchymal and focal liver lesions. Besides, we aimed to assess the influences of needle-related factors on the performance of EUS-LB. Additionally, we aimed to assess the influence of various criteria on specimen adequacy. Methods We searched the PubMed, Embase, Cochrane Library databases up to 10 October 2021. The primary outcome was diagnostic yield, specimen adequacy, qualified specimens evaluated by rapid on-site evaluation (ROSE). The secondary outcome was adverse events. Subgroup analyses were based on needle type, needle size, fine-needle biopsy (FNB) needle type. A sensitivity analysis was conducted on specimen adequacy based on two definition criteria. Results In total, 33 studies were included. Pooled rates of diagnostic yield, specimen adequacy, qualified specimen by ROSE, adverse events were 95%, 84%, 93%, 3%. Subgroup analyses showed that Acquire needles generated higher diagnostic yield than SharkCore needles (99% vs. 88%, p = .047). Additionally, FNB needles demonstrated a higher rate of adverse events than FNA needles (6% vs. 1%, p = .028). Sensitivity analysis on specimen adequacy based on various criteria demonstrated that the specimen adequacy rate defined by the AASLD criterion was lower than that of the commonly-used criterion (37% vs. 84%, p = .001). Conclusion EUS-LB is effective and safe for liver biopsy. Acquire needles provide better specimens than SharkCore needles. FNB needles may increase the risk of adverse events compared with FNA needles. The AASLD criterion is harder to achieve than the commonly-used criterion.
Aging in Place with Age-Related Cognitive Changes: The Impact of Caregiving Support and Finances

In the United States, aging in place is a common concept that refers to older adults’ desire to remain in their homes as they age. However, this ability to age in place is a complex process that is not only impacted by the home’s accessibility or individual functional abilities. This paper aims to examine different factors, such as home environment and home modification, caregivers, finances, and other supports present in the participants’ lives, that impact older adults with age-related cognitive changes (ARCC) (in)ability to age in place. Qualitative interviews with older adults with ARCC (n = 5) and their caregivers (n = 5) were conducted. The participants’ experiences while aging in place indicate that finances and caregiving support greatly impacted their lives at home and ability to age in place. Personal finances dictated where some of the participants could age and the support, they could afford from home health aides. Additionally, informal and formal caregivers were an important source of support that aided in the older adults’ ability to remain home. As researchers, we need to continue to address personal finances and the support that the individual has in their lives to most effectively promote aging in place and their life at home.
Plasma Amyloid-β in Relation to Antibodies Against Herpes Simplex Virus, Cytomegalovirus, and Chlamydophila pneumoniae

Background: Amyloid-β (Aβ), the key constituent of Alzheimer’s disease (AD) plaques, has antimicrobial properties. Objective: To investigate the association between plasma Aβ and antibodies against the AD-related pathogens herpes simplex virus (HSV), cytomegalovirus (CMV), and C. pneumoniae. Methods: Plasma from 339 AD cases, obtained on average 9.4 years (±4.00) before diagnosis, and their matched controls were analyzed for Aβ40 and Aβ42 concentrations with Luminex xMAP technology and INNOBIA plasma Aβ-form assays. Enzyme-linked immunosorbent assays were utilized for analyses of anti-HSV immunoglobulin (Ig) G, anti-HSV1 IgG, anti-HSV2 IgG, anti-CMV IgG, and anti-C. pneumoniae IgG. Follow-up samples were available for 150 of the cases. Results: Presence and levels of anti-HSV1 IgG, anti-HSV2 IgG, anti-CMV IgG, and anti-C. pneumoniae IgG did not correlate with concentrations of Aβ42 or Aβ40 in cases or controls. Conclusion: Levels of plasma Aβ were not associated with antibodies against different AD-related pathogens.
Achieving Equitable Social Health Insurance Benefits in China: How Does Domestic Migration Pose a Challenge?

Background: Universal coverage through social health insurance is promoted by many researchers and policymakers to improve health equity within a country or region. In China, the mass internal migration since 1980s has posed challenges for the social health insurance to ensure equitable benefits for migrant population. This study evaluated the benefit distribution of social health insurance among internal migrants in China.Methods: Using the 2014 China National Internal Migrants Dynamic Monitoring Survey, , by applying a two-part model, we conducted a benefit analysis of social health insurance among a representative sample of migrants in China.Results: The study found that the broader the geographic scope of migration, the lower the probability of receiving reimbursements from the social health insurance and the reimbursement ratio; but among those who received reimbursements, the broader the geographic scope of migration, the larger amounts they were reimbursed for health care use. We attributed this unequal benefit distribution to the current insurance design that replies on localized administration and patients paying services up-front and requesting reimbursement later.Conclusion: To improve the equity in social insurance benefits between migrants and non-migrants and among migrants, policies that promote the insurance portability across regions and immediate reimbursement are warranted, while at the same time efforts should be done to control inflation of health care expenditures and to prevent inverse government subsidies from the regions that have more out-migration to regions that have in-migration.
Youth Unemployment and its Origins: An Analyses of Multan District

Youth unemployment is one of the major problems which the developing countries of the world face. This study is initiated to explore the foremost origins and sequels of youth employment. The analyses rested at primary data collected from 400 respondents within the age group of 15 to 40 years of age. The Binary Logistic Probability Regression is incorporated to explore varied results at the opted variables. After the conclusion of results, it is suggested to improve education within the region to enable the youth to grab available job opportunity, enhance working experience, and therefore be in the category of employed youth.
Effects of customer trust on engagement in live streaming commerce: mediating role of swift guanxi

PurposeLive streaming commerce, a new form of social commerce where firms integrate with broadcasters, community members and customers in live chat rooms for real-time interaction to help sell products, has become increasingly popular. However, factors that impact the success of live streaming commerce are not fully explored. The purpose of this study is to examine these factors by exploring the relationships among customer trust (i.e., trust in broadcasters, community members, and products) and customer engagement, and the mediating role of swift guanxi.Design/methodology/approachThe authors surveyed 422 customers who have watched Taobao Live, one of the largest live streaming commerce sites in China, and used their questionnaires to test the research model employing partial least squares modeling.FindingsThe authors’ results indicate that trust in broadcasters has a positive effect on trust in products and community members, which positively influences trust in products. Additionally, swift guanxi has a fully mediating effect on the relationship between customers' trust in broadcasters and customer engagement.Originality/valueFirst, from the theoretical perspective, this study comprehensively identifies three types of trust, explores the transfer relationships among trust in broadcasters, community members, and products based on Trust Transfer Theory. In addition, this study examines the mediating influence of swift guanxi on the relationship between customer trust and engagement. Second, from the managerial perspective, the study provides insights to help broadcasters and practitioners use live streaming to facilitate shopping.
BIOLOGICAL ACTIVITIES OF THE ESSENTIAL OIL AND ETHANOLIC EXTRACT OF Inula viscosa FROM THE TLEMCEN REGION OF ALGERIA

Inula viscosa is a medicinal plant used for certain therapeutic treatments. In this work the antimicrobial and antioxidant activities of essential oil and ethanolic extract of this plant were examined. The activity of these extracts was tested against 8 bacteria, as well as 5 moulds and yeasts. They presented a weak antibacterial capacity. The antifungal activity of the essential oil is higher than that of the ethanolic extract, with an inhibition ranging from 56.75% to 84.11%. The antioxidant activity of the essential oil was evaluated with the 2,2-diphenyl-l-picrylhydrazyl (DPPH') radical scavenging method. Tests of the activity of the ethanolic extract were carried out using three methods: reducing power, superoxide anion scavenging assay and DPPH* radical scavenging test. These tests revealed that the essential oil has a weak antiradical capacity. The ethanolic extract possessed a weak reducing power and superoxide anion scavenging activity, but a strong inhibition of DPPH* radical.
Nonlocal contrast calculated by the second order visual mechanisms and its significance in identifying facial emotions

Background: Previously obtained results indicate that faces are / preattentively/ detected in the visual scene very fast, and information on facial expression is rapidly extracted at the lower levels of the visual system. At the same time different facial attributes make different contributions in facial expression recognition. However, it is known, among the preattentive mechanisms there are none that would be selective for certain facial features, such as eyes or mouth. The aim of our study was to identify a candidate for the role of such a mechanism. Our assumption was that the most informative areas of the image are those characterized by spatial heterogeneity, particularly with nonlocal contrast changes. These areas may be identified / in the human visual system/ by the second-order visual / mechanisms/ filters selective to contrast modulations of brightness gradients. Methods: We developed a software program imitating the operation of these / mechanisms/ filters and finding areas of contrast heterogeneity in the image. Using this program, we extracted areas with maximum, minimum and medium contrast modulation amplitudes from the initial face images, then we used these to make three variants of one and the same face. The faces were demonstrated to the observers along with other objects synthesized the same way. The participants had to identify faces and define facial emotional expressions. Results: It was found that the greater is the contrast modulation amplitude of the areas shaping the face, the more precisely the emotion is identified. Conclusions: The results suggest that areas with a greater increase in nonlocal contrast are more informative in facial images, and the second-order visual / mechanisms/ filters can claim the role of /filters/ elements that detect areas of interest, attract visual attention and are windows through which subsequent levels of visual processing receive valuable information.
An Exploratory study of the Influence of Psychological Capital on Indian Entrepreneurs in Developing Crisis Intervention Strategies amidst the COVID-19 Pandemic

The primary purpose of this study was to investigate the influence of psychological capital on entrepreneurs in developing crisis intervention strategies to mitigate the impact of the COVID-19 crisis. Psychological Capital (PsyCap) is a multidimensional construct of positive psychology that includes the psychological capacities of Hope, Efficacy, Resilience and Optimism. This research examined (a) how the construct of psychological capital influenced entrepreneurs, and (b) how this causality between entrepreneurs’ psychological capital and formulating crisis intervention strategies enabled them to navigate through the pandemic by adopting response and recovery strategies on an individual level and on an organizational level. A Multiple Case Study design was incorporated into this study to provide extensive explanations of the influence of PsyCap by assessing the causation of PsyCap on entrepreneurs across several industries. The findings of the study suggested that psychological capital can play a positive role on entrepreneurs that facilitated in building capabilities for survival of the firm by (a) analysing the challenges and executing intervention plans, (b) integrating employee wellbeing and innovation strategies, and (c) enduring the crisis and leading out successfully. Furthermore, this research contributes to the extant literature of entrepreneurship and positive organizational behaviour by providing empirical evidence depicting the multifaceted characteristics of psychological capital.
Feasibility analysis of a two-phase solar thermal water heater

Experiments were conducted to measure the heat transfer characteristics of nonboiling two-phase segmented flow in a solar thermal collector. The solar thermal collector was manufactured to have a serpentine flow path (residential serpentine deign) and the diameter of collector pipe was 0.0109 m. The working fluids used in the experiments were water, ethylene glycol and air. Single phase water was examined first, and the results were used as a basis for comparison for the water-air two-phase flow results. Two-phase experiments using ethylene glycol-air and single phase ethylene glycol were then conducted. The flow rates of the water-air and ethylene glycol-air phases were varied between a range of values during each experiment and the system pressure and temperatures were recorded at each combination of flow rates. The experimental data was used to calculate the number of variables, such as the heat transfer rate Q , temperature difference between the entrance and exit of the solar thermal collector [delta]T , average bulk temperature b T , the time required for raising the temperature inside the tank from 25℃ to 70℃, and the energy gained from the tank E . It has been shown that the heat transfer enhancement of two-phase flow system was better than the single phase flow system. Several experiments were conducted to study the effects of liquid void fraction αl. The effect of liquid void fraction showed that the heat transfer rate was highest in all experiments when the liquid void fraction was 0.5, while the heat transfer rate was at its lowest value when the liquid void fraction was 0.79. The effect of void fraction was found to be a controlling factor due to its impact on liquid slug length, which in turn affects the heat transfer rate. Finally, the four two-phase experiments were compared with single phase flow experiment. The result illustrated that the two-phase flow system was better than the single phase flow system.
Complexes cobalt(II), zinc(II) and copper(II) with some newly synthesized benzimidazole derivatives and their antibacterial activity

The preparation and properties of some complexes of cobalt(II), zinc(II) and copper(II) with several newly synthesized benzimidazole derivatives (L) are reported. The complexes, of the general formula [MCl2L2] (M=Co(II), Zn(II)) and [CuCl2L(H2O]), have a tetrahedral structure. The complexes were characterized by elemental analysis, molar conductivity, magnetic susceptibility measurements, IR and absorption electronic spectra. The antibacterial activitiy of the benzimidazoles and their complexes was evaluated against Erwinia carotovora subsp. carotovora and Erwinia amylovora. The complexes were found to be more toxic than the ligands.
Cracks in the well-plastered façade of the Nordic model: reflections on inequalities in housing and mobility in (post-)coronavirus pandemic Sweden

ABSTRACT In this paper, Sweden’s situation in and response to the COVID-19 pandemic is discussed. Through examples of overcrowding and public transport, we argue that the pandemic has revealed, and risks reaffirming, existing aged, gendered, ethnic and socioeconomic inequalities in the housing market, and in relation to mobility and transport. The paper seeks to explore how the large scale and widespread housing segregation in Sweden contributes to the unequal spread of the COVID-19 pandemic. More specifically, we address how the COVID-19 pandemic has affected and continues to affect the mobility of children, young people and families in unequal transport systems.