Miracle-dz/UniFAR-FTUs huggingface dataset:
Early and Late Changes in the Glycoproteins of Friend Erythroleukemia Cells Induced to Differentiate1

Incorporation of labeled fucose and galactose into Friend virus-transformed murine erythroleukemia cells, uninduced and induced to differentiate by hexamethylene bisacetamide, was followed during the first 4 days of treatment. The plasma membrane and microsomal-mitochondrial fractions of the cells were isolated and purified. The rate of fucose and galactose incorporation into membranal proteins was markedly stimulated in the induced cells as compared to the uninduced cells. However, the total amount of the label incorporated was de creased. Binding of wheat germ agglutinin to M.W. 140,000 and 90,000 bands of the plasma membrane was increased within 24 hr of induction and occurred at the same time as increased fucose incorporation into protein bands of similar size. Stimulation of concanavalin A binding to the plasma membrane proteins within 74 hr of induction was correlated with increased galactose incorporation into M.W. 32,000 and 64,000 bands which were tentatively identified as the glycophorin bands.
An Excellent Strategy In Reducing Turnover Intention At Permata Keluarga Bekasi Hospital

: This research actually aims to discover way out in reducing turnover intention from nurses at Permata Keluarga Bekasi Hospital. This research used quantitative method by causality approach and were analyzed with multiple linear regression analysis and path analysis. These research Population were all nurses who served in outpatient polyclinics at Permata Keluarga Bekasi Hospital, but samples taken were only 110 respondents. From this research was found that nurses' turnover intention could be reduced by decreasing their 'work stress, increasing a conducive work environment and increasing theirs organizational commitment. Organizational commitment could play role as a mediator for the impact from work stress on nurse's turnover intention, but it cannot mediate those impact from work environment on nurse's turnover intention. Hospitals could reduce nurse's turnover intention through personal approach, good communication and good appreciation towards them. Next researcher need to considers different research contexts with wider object research.
Multiferroic BiFeO 3 for Photovoltaic Applications : A First-principles Study

Ferroelectric materials are new candidates for photovoltaic materials. Ferroelectrics can produce photocurrents without using p-n junction which is necessary for conventional photovoltaic devices. BiFeO3 is one of the most promising multiferroic materials having band gap of 2.5 eV. This band gap is too wide to be used as photovoltaic devices, therefore lower band gap is necessary. In order to reduce BiFeO 3 band gap, we carry out a ﬁrst-principles calculation. We study Cu substitution impurities. We introduce a single Cu atom in the 2x2x2 supercell and we ﬁnd that the band gap is reduced by 0.039 eV. We expect the existence of optical transition energy between valence and impurity band with energy value 1.232 eV lower than the band gap of BiFeO 3 .
HUMAN CONTROL OF A FLEXIBLE OBJECT: HITTING A TARGET WITH A BULL-WHIP

Over the past decades research in computational motor neuroscience has proposed that human control of target-oriented movements relies on internal models of the body and the environment. Developed in control theory, supporting evidence in human movements has come from simple tasks with carefully controlled conditions. However, these movements are far removed from the dexterous interactions with complex objects that humans perform on a daily basis. When considering whole-body movements and interactions with complex objects, generalization of these control concepts faces an exponential increase in computational complexity. An alternative approach adopts a dynamic systems perspective hypothesizing that the high-dimensional, nonlinear, dynamic system of the human body has emergent patterns with stability, attractors, that may reduce the burden of control. This thesis developed a new experimental paradigm that examined whole-body actions in interaction with a complex object: a bullwhip. A bullwhip has infinitely many degrees of freedom, and only the handle is under direct control. Participants attempted to hit a target with the 1.60m-long whip either in discrete fashion, with a pause between each throw of the whip, or in rhythmic fashion, where the whip never came to rest between throws. Five successive blocks of each style comprised about 165 throws. Body and whip kinematics were recorded with marker-based motion capture. Data recording and processing of such extremely fast and complex actions required the development of novel markers and gap filling methods, including methods for reconstructing the whip continuum. Performance of 16 participants was quantified by success rate, error and variability of error. All measures showed better performance in the discrete style, although improvements only occurred in the rhythmic style. Tangential hand speed revealed twopeaked speed profiles for both discrete and rhythmic styles. The preparatory phase in the rhythmic style was shorter. Whip motion showed smoother unfolding in the rhythmic style, suggesting smoother energy propagation along the whip. This study presents the first step in a new experimental paradigm that challenges current motor control notions and sets the stage for more hypothesis-driven analysis.
OPTH_A_260000 2453..2462

1Department of Ophthalmology, Klinikum Chemnitz gGmbH, Chemnitz 09116, Germany; 2Ophthalmology Department, University Hospital Carl Gustav Carus, Technische Universitaet Dresden, Dresden, Germany Purpose: To investigate the reflectivity changes of inner retinal layers in acute retinal vein occlusion (RVO) on spectral-domain optical coherence tomography (SD-OCT) and to correlate these values with other known parameters of acute ischemic damage. Patients and Methods: In this retrospective and observational case series, 230 eyes from 115 patients with acute RVO (central or branch) were categorized as ischemic or nonischemic depending on fluorescein angiography (FA) images at baseline. Thickness and reflectivity of selected retinal layers were measured from SD-OCT images at baseline. Reflectivity values were correlated with other parameters of acute ischemic damage (bestcorrected visual acuity (BCVA), retinal thickness, extent of macular edema, ischemic area on fluorescein angiography). The data were compared with contralateral eyes (controls). Prominent middle limiting membrane sign (p-MLM) was also registered. Results: RVO reflectivity values differed significantly in all retinal layers compared to controls (P<0.001). Ischemic RVO eyes had higher optical intensity values for the innermost retinal layer (IMRL; P=0.008) and inner retinal layer (P=0.019) compared to non-ischemic cases. For all RVO eyes as well as central RVO, severity parameters like BCVA, central and total retinal thickness showed a strong correlation with the IMRL reflectivity. In branch RVO, BCVA remained significantly correlated with the IMRL reflectivity, while the thickness values showed significant correlation only for central foveal thickness in non-ischemic branch RVO type. The p-MLM was seen on OCT in 94% of the ischemic and in 66% of the non-ischemic RVO cases. Conclusion: Acute RVO leads to increased reflectivity of inner retinal layers with significantly higher values in the ischemic vs non-ischemic type. Increased inner retinal layers’ reflectivity correlated significantly with BCVA, retinal thickness of separate retinal layers, as well as ischemic area on FA. Quantitative non-invasive measurement of inner retinal layers’ reflectivity might be used to determine the extent of acute ischemic retinal damage in RVO.
Estimate of confidence in paleomagnetic directions derived from mixed remagnetization circle and direct observational data

A method is presented for obtaining the di rection and confidence oval for a paleomagnetic com ponent at a site given a number of independently ori ented samples, some of which give an estimate of the remanence direction, while others yield only remagneti zation circles. Such mixed remagnetization circle-re manence direction data frequently characterise pa leomagnetic sites carrying two remanence com ponents where the component of interest is small and less dispersed compared to a more easily removed one. The method described maximises the amount of usable data per site and thus leads to an improved site direc tion estimate.
Suppression of Steady-state, but not Stimulus-induced NF- (cid:107) B Activity Inhibits Alphavirus-induced Apoptosis

Recent studies have established cell type– specific, proapoptotic, or antiapoptotic functions for the transcription factor NF- (cid:107) B. In each of these studies, inhibitors of NF- (cid:107) B activity have been present before the apoptotic stimulus, and so the role of stimulus-induced NF- (cid:107) B activation in enhancing or inhibiting survival could not be directly assessed. Sindbis virus, an alphavirus, induces NF- (cid:107) B activation and apoptosis in cultured cell lines. To address whether Sindbis virus– induced NF- (cid:107) B activation is required for apoptosis, we used a chimeric Sindbis virus that expresses a superrepressor of NF- (cid:107) B activity. Complete suppression of vi-rus-induced NF- (cid:107) B activity neither prevents nor potentiates Sindbis virus–induced apoptosis. In contrast, inhibition of NF- (cid:107) B activity before infection inhibits Sindbis virus–induced apoptosis. Our results demonstrate that suppression of steady-state, but not stimulus-induced NF- (cid:107) B activity, regulates expression of gene products required for Sindbis virus–induced death. Fur-thermore, we show that in the same cell line, NF- (cid:107) B can be proapoptotic or antiapoptotic depending on the death stimulus. We propose that the role of NF- (cid:107) B in regulating apoptosis is determined by the death stimulus and by the timing of modulating NF- (cid:107) B activity rel-ative to the death stimulus.
TOO OLD TO VOTE? On reasons for non-voting at old age

It is well-known that voting participation declines with old age, but the reasons are largely unknown. Uninterest in the oldest and routine assumptions that the participatory decline among seniors is something natural deriving from deteriorating health, have likely contributed to the scarce amount of explanations to their non-voting. The few available studies that explore the phenomenon use quantitative measures, which neglects individual reasoning. The process of demographic aging in most Western societies highlights the urgency of information on the reasons for non-voting among the oldest citizens, if the unequal participation of the oldest is not to become a democratic issue in the future. This thesis undertakes an initial step of exploration, in defining and categorizing individual-level reasons for non-voting at old age among Swedish seniors who are 80+, using a qualitative approach. It finds reasons that range from the internal to the external; from not being able to out of poor health or a lack of engagement, assistance or information; to not wanting to out of a lack of engagement or efficacy. Altogether, the existing literature offers a basic understanding of the reasons for non-voting presented in this thesis, but it is far from sufficient for capturing the whole picture. The contributions of this thesis can be utilized both as a starting point for future research and for diversifying the societal and scientific conversation about the status of the oldest citizens in our democracies.
The Two-Sample t-test and the Influence of Outliers

This study investigates how outliers of different magnitude impact the robustness of the two-sample t-test. A simulation study approach is used to analyze the behavior of type I error rates when outliers are added to generated data. Outliers may distort parameter estimates such as the mean and variance and cause misleading test results. Previous research has shown that Welch’s t-test performs better than the traditional Student’s t-test when group variances are unequal. Therefore these two alternative statistics are compared in terms of type I error rates when outliers are added to the samples. The results show that control of type I error rates can be maintained in the presence of a single outlier. Depending on the magnitude of the outlier and the sample size, there are scenarios where the t-test is robust. However, the sensitivity of the t-test is illustrated by deteriorating type I error rates when more than one outlier are included. The comparison between Welch’s t-test and Student’s t-test shows that the former is marginally more robust against outlier influence.
Wind tunnel experiment of UTM-LST generic light aircraft model with external store

This paper discusses the impact of the external store on the aerodynamic performance of the light aircraft model in the subsonic region. Light aircrafts are commonly used for pilots training, survey, leisure and transportation. To date, there have been a lot of small aircrafts used for strategic purposes where an external store, either external fuel storage or armament, has been installed on its wing. Examples of such aircraft are KAI-KA1, A29 Super Tucano, and Beechcraft AT-6. Therefore, it is important to study the effect of this external store installation on the aerodynamic characteristics of a small aircraft. An available light aircraft model of UTM Low speed wind tunnel (UTM-LST) has been modified so that a generic external store can be mounted on the lower surface of the wing. Two set of experiments were carried out on the model which were; experimental with an external store followed by experimental without external store as a benchmark of tested configuration. The experiments were conducted at two different speeds of 26 and 39 m / s that correspond to Reynolds numbers 0.4 × 10 and 0.6 × 10respectively. Three measurement techniques were employed on each configuration. The first measurement was the 6 component forces and moments measurement technique. The second technique was the pressure measurement on the wing, and the final test was the tufts flow visualization. The result of steady balance indicated that the external store has no effect on the coefficient of lift at low attack angle. However, it showed that there was a reduction of lift coefficient by 2% at higher angle of attack. The data showed that the coefficient of drag increases by 4% when the external is installed. Surprisingly, the installation of the store has insignificant effects on the pitching moment coefficient. An interesting feature observed from surface pressure studies where, the results showed that the pressure coefficient increased when the external is mounted on the wing at a low angle of attack. Such changes, however, do not occur at high angle of attack. Copyright© 2018 Praise Worthy Prize S.r. l. All rights reserved.
Approximating Betweenness Centrality to Identify Key Nodes in a Weighted Urban Complex Transportation Network

The key nodes in a complex transportation network have a significant influence on the safety of traffic operations, connectivity reliability, and the performance of the entire network. However, the identification of key nodes in existing urban transportation networks has mainly focused on nonweighted networks and the network information of the nodes themselves, which do not accurately reflect their global status. Thus, the present study proposes a key node identification algorithm that combines traffic flow features and is based on weighted betweenness centrality. This study also uses weighted roads to construct an L-space weighted transportation network and an approximate algorithm for betweenness centrality in order to reduce the complexity of the calculations. The results of the simulation indicate that the proposed algorithm is not only capable of identifying the key nodes in a relatively short amount of time, but it does so with high accuracy. The findings of this study can be used to provide decision-making support for road network management, planning, and urban traffic construction optimization.
Stimulation of Ca 2+ -Gated Cl - Currents by the Calcium-Dependent K + Channel Modulators NS1619 and Isopimaric Acid

ClCa I BKCa , Calcium-activated potassium current; I ClCa , Calcium-activated chloride I late , Current measured at the end of a voltage clamp test pulse; I initial , Current measured at the of a voltage clamp test pulse immediately following the capacitative current; I tail ; measured 20 ms after repolarization from a voltage clamp step used to elicit time-dependent calcium-activated chloride current; I-V, Current-voltage relationship; IpA, Isopimaric acid; NFA, Niflumic acid; NP 0 , Number of open channels times the open probability; 1,3-Dihydro-1-[2-hydroxy-5-(trifluoromethyl)phenyl]-5-(trifluoromethyl)-2H-benzimidazol-2-one Abstract As chloride (Cl - ) channel blockers such as niflumic acid enhance large conductance Ca 2+ activated potassium channels (BK Ca ) the aim of this study was to determine if there is a reciprocal modification of Ca 2+ -activated chloride Cl - currents ( I ClCa ) by two selective activators of BK Ca . Single smooth muscle cells were isolated by enzymatic digestion from murine portal vein and rabbit pulmonary artery. The BK Ca activators NS1619 and isopimaric acid (IpA) augmented macroscopic I ClCa elicited by pipette solutions containing [Ca 2+ ] i > 100 nM without any alteration in current kinetics. Enhanced currents recorded in the presence of NS1619 or IpA reversed at the theoretical Cl - equilibrium potential, which was shifted by ~ −40 mV upon replacement of the external anion with the more permeable thiocyanate anion. NS1619 increased the sensitivity of Cl Ca channels to Ca 2+ (~ 100 nM at +60 mV) and induced a leftward shift in their voltage-dependence (~ 80 mV with 1 µM Ca 2+ ). Single channel experiments revealed that NS1619 increased the open probability (NP 0 ) of small conductance (1.8 – 3.1 pS) Cl Ca channels without any alteration in their unitary amplitude or number of observable unitary levels of activity. These data, in addition to the established stimulatory effects of NFA on BK Ca , show that there is similarity in the pharmacology of calcium-activated chloride and potassium channels. Whilst non-specific interactions are possible, one alternative hypothesis is that the channel underlying vascular I ClCa shares some structural similarity to the BK Ca channel or that the latter K + channel physically interacts with Cl Ca channels. subsequent application NFA. These results suggest that the channel underlying I ClCa
How Agile Am I? An Initial Analysis of Student Reflective Narratives of Their Employability and Enterprise Development. Karen Clinkard 33 Digital Greek Start-Ups-An Analysis of Founders Perceptions

This paper contributes to debate of the relevance of current measures of employability and entrepreneurial (E&E) outcomes from Higher Education (HE). Given current metrics are often reliant upon statistics at predominately general, cohort level as a one-off cross-section (e.g. DLHE); are they fit for evaluating longer term E&E gains from a University experience? Does attempting to perform against exit performance metrics engender positive or negative responses? Educators and employers increasingly argue E&E outcomes should not focus heavily on hard skills, but a broader range of behavioural, attitudinal and mindset changes, claiming these provide more sophisticated bases for exploring the longitudinal value of the HE experience. Relatedly, this paper asks is there value in individual students contributing contextualised insight, in the form of their own E&E development narrative? Qualitative and quantitative data gathered from approximately 300 Undergraduate students at a UK business school, using the AGILE self-reflection tool, are evaluated to investigate correlations between student demographics, subject studied and exposure to enterprise education (EE), as variables, affecting E&E development. Initial findings indicate that certain self-reported AGILE scores increase as students get older and progress through levels of their course, whilst others do not. The aim is to further discussion relevant to all HE stakeholders (including staff in careers and entrepreneurial services, teachers, programme leaders, strategic 5 decision makers, students, employers and policy makers), regarding E&E development and outcome measures. Importantly, it is hoped readers perceive valuable insights for enhancing curricula, through identification of tangible benefits to students, from adopting AGILE mindset development.
Free vibration analysis of functionally graded carbon nanotubes reinforced composite skew folded plates using isogeometric approach

In this research, an approach based on isogeometric method is developed to study free vibration behavior of functionally graded carbon nanotubes reinforced composite skew folded plates. In this method, Non-Uniform Rational B-Splines (NURBS) basis functions are used for approximation of the geometry as well as the displacement field. The plates are reinforced by single-walled carbon nanotubes which are assumed to be graded through the thickness direction with different distribution patterns. The effective mechanical properties of composite skew folded plates are captured by the modified rule of mixtures approach. Modeling of the skew folded plate is accomplished by two NURBS patches which is one of the strengths of the research. The equations of motion of each patch are derived based on classical plate theory and then are discretized using NURBS basis functions. The final form of the discretized equations is generated after transformation of the element matrices of each patch and then applying the continuity conditions along the boundary of the patches with the aid of bending strip method. Afterward, several numerical examples are provided to prove the accuracy and reliability of the proposed formulation. The results exhibit that the present approach can precisely predict the natural frequencies of skew folded plates with a low computational cost. Eventually, a set of new results are presented for different geometrical and material parameters of the skew folded plate.