Miracle-dz/UniFAR-FTUs huggingface dataset:
Instant Volume Visualization using Maximum Intensity Difference Accumulation

It has long been recognized that transfer function setup for Direct Volume Rendering (DVR) is crucial to its usability. However, the task of finding an appropriate transfer function is complex and time‐consuming even for experts. Thus, in many practical applications simpler techniques which do not rely on complex transfer functions are employed. One common example is Maximum Intensity Projection (MIP) which depicts the maximum value along each viewing ray. In this paper, we introduce Maximum Intensity Difference Accumulation (MIDA), a new approach which combines the advantages of DVR and MIP. Like MIP, MIDA exploits common data characteristics and hence does not require complex transfer functions to generate good visualization results. It does, however, feature occlusion and shape cues similar to DVR. Furthermore, we show that MIDA – in addition to being a useful technique in its own right – can be used to smoothly transition between DVR and MIP in an intuitive manner. MIDA can be easily implemented using volume raycasting and achieves real‐time performance on current graphics hardware.
of the 11 S Proteasome Regulator-Subunit α Interaction between the Protein Kinase B-Raf and the Updated Version

Protein kinases of the Raf family act as signal-transducing elements downstream of activated cell surface receptors and are involved in the regulation of proliferation, differentiation, and cell survival. Whereas the role of c-Raf-1 as a mitogen-activated protein/extracellular signal-regu lated kinase activator within the mitogenic cascade is well established, less is known about the mammalian Raf isoforins A-Raf and B-Raf. Here we report that B-Raf binds to PA28a, one of two subunits of the 1IS regulator of proteasomes. PA28<* was isolated as a B-Raf-binding protein in a yeast two-hybrid screen of a PC 12 cDNA library. Both proteins can be coimmunoprecipitated after transient expression in 293 cells. No association could be found between PA2Sa and A-Raf or c-Raf-1. B-Raf binds to a region in PA28a that is important for its proteasome-activating function.
A new service development process for a logistic service provider

3 List of Figures . 6 List of Tables . 6 Abbreviations . 6 Management summary . 8 Preface . 10 1. Research Context. 11 1.
Initial Antihypertensive Drug Therapy Final Report of a Randomized, Controlled Trial Comparing a‐Blocker and Diuretic

We compared the effect on serum Upids of an α-blocker (prazosin) and a diuretic (hydrochlorothiazide) used as initial antihypertensive drug treatment for 102 men and women with less severe hypertension (average entry blood pressure, 148/97 mm Hg, with no major organ system damage). A two-center trial randomized patients to treatment with either prazosin or hydrochlorothiazide; the alternate drug was added if adequate blood pressure control was not achieved with the originally assigned drug, and patients were removed from any drug they were not able to tolerate. After an average of 40 weeks on the assigned drug regimen, a decline was observed in prazosin-treated patients in both serum total cholesterol (−9.3 mg/dl) and serum triglycerides (−33.9 mg/dl). In contrast, an increase in both these Upids was seen in hydrochlorothiazide-treated patients (+5.0 mg/dl for serum total cholesterol and + 18.6 mg/dl for serum triglycerides). The net trial differences between the groups were 14.3 mg/dl for total cholesterol and 52.5 mg/dl for triglycerides, in favor of prazosin (p < 0.001 for both comparisons). These differences in Upids between the two groups persisted into the second year of the trial (p < 0.05). There were no significant differences between the drug groups in regard to the level of high density Upoprotein cholesterol or its subtractions or low density Upoprotein cholesterol. In patients who required a combination of the two drugs to achieve blood pressure control, the a-blocker diminished or eliminated the Upid-raising effects of the diuretic. Both drugs were similar in their ability to control the elevation of diastoUc pressure. More patients were unable to tolerate prazosin than were unable to tolerate hydrochlorothiazide. For those able to continue with prazosin, either as the single initial treatment or in combination with hydrochlorothiazide, the lipki response appeared to be an asset in regard to avoiding possible atherogenic effects of treatment and thereby possibly reducing coronary risk.
Architecture and Protocols of the RAMPE system- An Interactive Auditive Machine Helping Blinds in Public Transport

This paper presents the RAMPE system intended to assist and help blinds and visual-impaired people in public transportation. This system relies on a network which must provide open connection and access protocol for the user. The network architecture of this system is described along with the different protocols in use, their limitations and the possible enhancements. The simulation of the RAMPE application level with OMNET++ is also presented
Phone Elasticity in Disfluent Contexts

Disfluencies in speech are instances of hesitation or correction that affect both the speaker and the listener. Typical surface forms of disfluencies are filled pauses (such as uh, uhm), silences at places in the utterance where syntax would not predict them, or repetitions of parts of the utterance (like (I mean + I mean) we should go). Disfluencies carry a folk notion of erroneousness or badness. Voice coaches often advise to eliminate disfluencies such as filled pauses from speech. Research in the past decades began to put disfluencies into a more positive light, as it was discovered that they provide the listener with important meta-information about the current speech from their interlocutor. Listeners can infer difficulties of reference or problems of forming the right speech plan when they hear the speaker hesitate (See [1] for an overview). We largely follow the view of [2], who formulated the new perspective on disfluencies as them being solutions, not problems. Recent studies started investigating the question if disfluencies are suitable for human-machine communication as well, cf. [3]. One of the possible places of applicability is incremental spoken dialogue systems. Compared to non-incremental systems, these systems can prepare their response to human speech input in real-time while the user is speaking and can thus respond with only milliseconds delay, cf. figure 1. This, however, can cause problems such as running out of things to say or uttering erroneous output which needs correction. It is an open question whether disfluencies can remedy these issues by equipping incremental spoken dialogue systems with human features of dialogue management in order to solve these problems in addition to sounding more natural. With the aim in mind to improve the quality of incremen-
Double Heterozygous Mutations Involving Both HNF1A/MODY3 and HNF4A/MODY1 Genes

OBJECTIVE We describe a maturity-onset diabetes of the young (MODY) case with mutations involving both HNF4A and HNF1A genes. RESEARCH DESIGN AND METHODS A male patient was diagnosed with diabetes at age 17; the metabolic control rapidly worsened to insulin requirement. At that time no relatives were known to be affected by diabetes, which was diagnosed years later in both the parents (father at age 50 years, mother at age 54 years) and the sister (at age 32 years, during pregnancy). RESULTS The genetic screening showed a double heterozygosity for the mutation p.E508K in the HNF1A/MODY3 gene and the novel variant p.R80Q in the HNF4A/MODY1 gene. The genetic testing of the family showed that the father carried the MODY3 mutation while the mother, the sister, and her two children carried the MODY1 mutation. CONCLUSIONS MODY1 and MODY3 mutations may interact by chance to give a more severe form of diabetes (younger age at presentation and early need of insulin therapy to control hyperglycemia).
Simple algebraic structure of Taylor expansion of sampled-data systems

The relation between the continuous-time model and the corresponding discrete-time model of sampled-data system has not been believed to be very simple. However, from the view point of Taylor expansion with respect to sample time, the relation is approximated by unexpectedly simple polynomials. In this paper, we show that there is a simple regularity in Taylor expansion for any sampled-data systems. Next, it is demonstrated that the regularity reduces symbolic calculation of the Taylor expansion. Finally, we apply the result to identification of continuous-time model from discrete-time input-output data of sampled-data systems based on optimization techniques.
A Structural Model Decomposition Framework for Hybrid Systems Diagnosis

Nowadays, a large number of practical systems in aerospace and industrial environments are best represented as hybrid systems that consist of discrete modes of behavior, each defined by a set of continuous dynamics. These hybrid dynamics make the on-line fault diagnosis task very challenging. In this work, we present a new modeling and diagnosis framework for hybrid systems. Models are composed from sets of user-defined components using a compositional modeling approach. Submodels for residual generation are then generated for a given mode, and reconfigured efficiently when the mode changes. Efficient reconfiguration is established by exploiting causality information within the hybrid system models. The submodels can then be used for fault diagnosis based on residual generation and analysis. We demonstrate the efficient causality reassignment, submodel reconfiguration, and residual generation for fault diagnosis using an electrical circuit case study.
Cooperative Runtime Monitoring of LTL Interface Contracts

Requirements on message-based interactions can be formalized as an interface contract that specifies constraints on the sequence of possible messages that can be exchanged by multiple parties. At runtime, each peer can monitor incoming messages and check that the contract is correctly being followed by their respective senders. We introduce cooperative runtime monitoring, where a recipient "delegates" its monitoring task to the sender, which is required to provide evidence that the message it sends complies with the contract. In turn, this evidence can be quickly checked by the recipient, which is then guaranteed of the sender's compliance to the contract without doing the monitoring computation by itself. A particular application of this concept is shown on web services, where service providers can monitor and enforce contract compliance of third-party clients at a small cost on the server side, while avoiding to certify or digitally sign them.
Immigrant-Native Differences in Welfare Participation: The Role of Entry and Exit Rates

This paper analyzes differences in welfare transitions between natives and immigrants in Sweden using a large representative panel data set, LINDA, for the years 1991 to 2001. The data contains administrative information on welfare use, country of birth, and time of arrival in Sweden among other things, and provides an excellent opportunity to examine immigrantnative differences in welfare use. The empirical results suggest that the main reason for the large immigrant-native welfare gap observed in the data is differences in welfare entry rates. Thus, policies aimed to reduce these transitions may be particularly successful in reducing welfare use in general and the immigrant-native welfare gap in particular.
Input-output finite-time stability and stabilization of stochastic Markovian jump systems

In this paper, we introduce a new concept named input-output finite-time mean square stability (IO-FTMSS) for stochastic Markovian jump systems. In contrast to the available notions of stochastic stability, IO-FTMSS characterizes the input-output behavior of dynamics on a finite time horizon. Concerning a class of random input signals LT2, the problems of input-output finite-time mean square stability and stabilization are investigated for both linear and nonlinear stochastic systems perturbed by Markovian processes. Sufficient conditions are derived in terms of coupled linear matrix inequalities (LMIs) and Hamilton-Jacobi inequalities (HJIs), respectively. In addition, a numerical example is supplied to illustrate the proposed technique.
Notice of RetractionOptimization design for planar four-bar mechanism based on differential evolution

Mechanism kinematic synthesis, the identification of the parameters of a mechanism, has been extensively studied especially for four-bar linkages using graphical and numerical optimization approaches. The graphical method is simple, but the accuracy is lower. The analytical method can not be showed visually. The paper studies synthesis of planar linkage mechanisms by differential evolution method and develops the corresponding software. Differential evolution has some features such as simple to use, fast convergence speed and need little information about problems. Through researching, we found it is very suitable to solve some complex optimization problems. The design instances showed that the method was practicable and effective.
A note on a generalization of eigenvector centrality for bipartite graphs and applications

Eigenvector centrality is a linear algebra based graph invariant used in various rating systems such as webpage ratings for search engines. A generalization of the eigenvector centrality invariant is defined which is motivated by the need to design rating systems for bipartite graph models of time‐sensitive and other processes. The linear algebra connection and some applications are described. © 2011 Wiley Periodicals, Inc. NETWORKS, 2012
Proceedings of the LREC Workshop ‘VisLR II: Visualization as Added Value in the Development, Use and Evaluation of Language Resources’

The visualization of syntactic analyses may be challenging due to the number of readings, the size and detail of the structures, and the interrelations between levels of linguistic description. We present a range of interactive visualization techniques applied to complex syntactic analyses in INESS, an online infrastructure for parsing and the annotation and exploration of syntactically annotated corpora (treebanks). Although INESS caters to many syntactic formalisms, we focus on LFG, which allows for multiple levels of syntactic structure, in particular c-structures and f-structures. Interactive dynamic renderings of the relations between components of these structures are presented, with options on the level of detail to be displayed. Furthermore, the disambiguation of sentences with multiple possible parses needs techniques for visualizing the differences between readings. For this purpose, we present and discuss packed representations, the interactive visualization of discriminants, and the previewing of disambiguation choices. The interactive querying of treebanks benefits from appropriate ways of displaying search results. We present the highlighting of matching items in matching sentences. We also present tabular overviews with frequencies of obtained variable values, as well as the inspection of matching structures without having to navigate away from the overview.
Speech Emotion Recognition With TGI+.2 Classifier

We have adapted a classification approach coming from optical character recognition research to the task of speech emotion recognition. The classification approach enjoys the representational power of a syntactic method and efficiency of statistical classification. The syntactic part implements a tree grammar inference algorithm. We have extended this part of the algorithm with various edit costs to penalise more important features with higher edit costs for being outside the interval, which tree automata learned at the inference stage. The statistical part implements an entropy based decision tree (C4.5). We did the testing on the Berlin database of emotional speech. Our classifier outperforms the state of the art classifier (Multilayer Perceptron) by 4.68% and a baseline (C4.5) by 26.58%, which proves validity of the approach.
Dow Cancer esearch ention and Epidemiology ationship between Radiation Exposure and Risk of Second R ary Cancers among Atomic Bomb Survivors

nloaded iation exposure is related to risk of numerous types of cancer, but relatively little is known about its on risk of multiple primary cancers. Using follow-up data through 2002 from 77,752 Japanese atomic survivors, we identified 14,048 participants diagnosed with a first primary cancer, of whom 1,088 were sed with a second primary cancer. Relationships between radiation exposure and risks of first and primary cancers were quantified using Poisson regression. There was a similar linear dose-response nship between radiation exposure and risks of both first and second primary solid tumors [excess e risk (ERR)/Gy = 0.65; 95% confidence interval (CI), 0.57–0.74 and ERR/Gy = 0.56; 95% CI, 0.33–0.80, tively] and risk of both first and second primary leukemias (ERR/Gy = 2.65; 95% CI, 1.78–3.78 and y = 3.65; 95% CI, 0.96–10.70, respectively). Background incidence rates were higher for second solid s, compared with first solid cancers, until about age 70 years for men and 80 years for women (P < ), but radiation-related ERRs did not differ between first and second primary solid cancers (P = 0.70). ion dose was most strongly related to risk of solid tumors that are radiation-sensitive including second ry lung, colon, female breast, thyroid, and bladder cancers. Radiation exposure confers equally high e risks of second primary cancers as first primary cancers. Radiation is a potent carcinogen and those with relativ substantial exposures who are diagnosed with a first primary cancer should be carefully screened for second primary cancers, particularly for cancers that are radiation-sensitive. Cancer Res; 70(18); 7187–98. ©2010 AACR.
Cohort profile: The Cork and Kerry Diabetes and Heart Disease Study.

The primary aim ofthe study was to estimate the prevalence of majorCVD risk factors in a middle-aged population inIreland and to estimate the proportion of the popula-tion at high risk according to Framingham criteria.The study included measurement of diet and physicalactivity and assessed the impact of these lifestyle fac-tors on traditional CVD risk factors including hyper-tension and dyslipidaemia.
Temper Brittleness—An Interpretive Review

S: The history of the problem of temper brittleness is surveyed; the reviews of Hollomon, Woodfine, and Low are reexamined in the light of recent developments, and the work carried out since 1959 is reviewed. Included in the latter is a model which has been proposed to explain the phenomenon. The problem of "500 F embrittlement" and its connection with temper brittleness are discussed, and a rudimentary model is proposed. Suggested directions for future research are indicated.
Exploring Tissue Engineering: Vitamin D3 Influences on the Proliferation and Differentiation of an Engineered Osteoblast Precursor Cell Line During Early Bone Tissue Development

This Dissertation is brought to you for free and open access. It has been accepted for inclusion in Dissertations and Theses by an authorized administrator of PDXScholar. For more information, please contact pdxscholar@pdx.edu. Recommended Citation Mason, Shelley S. , "Exploring Tissue Engineering: Vitamin D3 Influences on the Proliferation and Differentiation of an Engineered Osteoblast Precursor Cell Line During Early Bone Tissue Development" (2013). Dissertations and Theses. Paper 1000.
Layered Clay Rubber Composites

The field of nanotechnology is one of the most popular areas for current research and development in virtually all technical disciplines. This obviously includes polymer science and technology. In recent year, researchers have been working on a new scale of reinforcement by incorporating a fine dispersion of clay silicatelayers in the polymer matrix to obtain polymer nanocomposites. Nanoscale layered clays, due to their high aspect ratio and high strength, can play an important role in forming effective polymer nanocomposites. Polymer nanocomposites have received much attention due to its large surface area and very high aspect ratio. Polymer nanocomposites especially rubber based nanocomposites is one of the many composite materials in which researchers and engineers have shown great interest due to their potential to be used in critical applications. Polymer layered silicate (PLS) nanocomposites often exhibit remarkable improvement in materials properties when compared with the virgin polymer or conventional micro and macro composites. These improvements can include high moduli and tear strength, improved heat resistance and electrical properties, decreased gas permeability, swelling to solvents and flammability.
Automated microscopy identifies estrogen receptor subdomains with large‐scale chromatin structure unfolding activity

Recently, several transcription factors were found to possess large‐scale chromatin unfolding activity; these include the VP16 acidic activation domain, BRCA1, E2F1, p53, and the glucocorticoid and estrogen steroid receptors. In these studies, proteins were fluorescently labeled and targeted to a multimerized array of DNA sequences in mammalian cultured cells, and changes in the appearance and/or size of the array were observed. This type of experiment is impeded by the low throughput of traditional microscopy.
Elaboration of a long-term maintenance plan for building stock based on arbitration using a risk approach

ABSTRACT The arbitration of a multi-year maintenance plan is one of the decision situations that a building facility manager can face. The complexity of the decision imposes the use of tools for decision support. A risk approach can be particularly efficient for solving this kind of problem. The challenge is to propose a risk-oriented method, adapted to building facility management. To do this, our method considers risk, but also the effectiveness and the cost of actions of risk mitigation. It proposes an ergonomic arbitration system, based on filters, following two complementary approaches: a selection of the fundamental actions and an optimization of the plan (viewed globally). The aim, for the decision-maker is to construct his own solution by testing multiple angles of vision in simulation logic. This article presents the principles of the method, illustrated by a real case conducted for a large company.