Miracle-dz/UniFAR-FTUs huggingface dataset:
The effect of anemia on the severity and prognosis of patients with acute pancreatitis: A single-center retrospective study

Anemia was a risk factor for a worse prognosis of many diseases. This study aims to investigate the relationship between anemia and the severity and prognosis of acute pancreatitis (AP). Inpatients hospitalized at the First Affiliated Hospital of Guangdong Pharmaceutical University with a primary diagnosis of AP between 1st July 2016 to 31st December 2020 were enrolled. Subsequently, disease severity, the incidence of complications, and the prognosis of patients with AP were compared between the anemic group and the non-anemic group. A total of 282 patients with acute pancreatitis were enrolled; 68.43% of them were also diagnosed with anemia. Notably, these patients had more severe disease (higher RANSON, acute physiologic assessment and chronic health evaluation-II, bedside index for severity in acute pancreatitis, and multiple organ dysfunction syndrome scores); higher incidence of organ failure (acute kidney injury [AKI] and acute heart failure); worse prognosis (higher incidence of vasoactive and diuretic agent use, longer hospital stays, and higher hospital costs) compared to that of patients without anemia (all P < .05). After adjusting for potential confounders, acute physiologic assessment and chronic health evaluation-II, bedside index for severity in acute pancreatitis, multiple organ dysfunction syndrome scores, hospital stay, and hospital costs in anemic patients were higher than those in non-anemic patients; besides, the incidence of AKI and using a diuretic agent in anemic patients was 6.645 and 4.053 times that of non-anemic patients in AP, respectively (all P < .05). Acute pancreatitis patients with anemia have more disease severity, higher incidence of AKI, and worse prognosis compared to those without anemia.
Beta-Meta: a meta-analysis application considering heterogeneity among genome-wide association studies

Many packages for a meta-analysis of genome-wide association studies (GWAS) have been developed to discover genetic variants. Although variations across studies must be considered, there are not many currently-accessible packages that estimate between-study heterogeneity. Thus, we propose a python based application called Beta-Meta which can easily process a meta-analysis by automatically selecting between a fixed effects and a random effects model based on heterogeneity. Beta-Meta implements flexible input data manipulation to allow multiple meta-analyses of different genotype-phenotype associations in a single process. It provides a step-by-step meta-analysis of GWAS for each association in the following order: heterogeneity test, two different calculations of an effect size and a p-value based on heterogeneity, and the Benjamini-Hochberg p-value adjustment. These methods enable users to validate the results of individual studies with greater statistical power and better estimation precision. We elaborate on these and illustrate them with examples from several studies of infertility-related disorders.
A novel five-variable refined plate theory for vibration analysis of functionally graded sandwich plates

Abstract In this article, a new five-variable refined plate theory for the free vibration analysis of functionally graded sandwich plates is developed. By dividing the transverse displacement into bending, shear, and thickness stretching parts, the number of unknowns and governing equations of the present theory is reduced, and hence, makes it simple to use. Indeed, the number of unknown functions involved in the present theory is only five, as opposed to six or more in the case of other shear and normal deformation theories. The theory accounts for hyperbolic distribution of the transverse shear strains, and satisfies the zero traction boundary conditions on the surfaces of the plate without using a shear correction factor. Two common types of functionally graded material (FGM) sandwich plates, namely, the sandwich with FGM facesheet and homogeneous core and the sandwich with homogeneous facesheet and FGM core, are considered. The equations of motion are obtained using Hamilton's principle. Numerical results of the present theory are compared with three-dimensional elasticity solutions and other higher-order theories reported in the literature. It can be concluded that the proposed theory is accurate and efficient in predicting the free-vibration response of functionally graded sandwich plates.
Population studies in groups and clusters of galaxies. III. A catalog of galaxies in five nearby groups

Five nearby groups of galaxies have been surveyed using large-scale plates from the 2.5 m duPont Telescope at Las Campanas Observatory. Catalogs of galaxies brighter than B(T) = 20 are presented for the Leo, Dorado, NGC 1400, NGC 5044, and Antlia groups. A total of 1044 galaxies are included, from visual inspection of 14 plates, covering 31 deg square. Galaxies have been classified in the extended Hubble system, and group memberships have been assigned based on velocity (where available) and morphology. About half the galaxies listed are likely members of one of the nearby groups. The catalogs are complete to B(T) = 18, although the completeness limits vary slightly from group to group. Based on King model fits to the surface density profiles, the core radii of the groups range from 0.3 to 1 Mpc, and central densities range from 120 to 1900 galaxies Mpc exp-3 brighter than M(BT) = -12.5. Dynamical analysis indicates that all of the groups are likely to be gravitationally bound. 64 refs.
Ruby and Sm:YAG fluorescence pressure gauges up to 120 GPa and 700 K

Diamond anvil cell (DAC) technique relies on pressure determination based on use of pressure gauges. Fluorescence-based gauges, such as ruby and Sm doped yttrium aluminum garnet (Sm:YAG), are frequently used in the high pressure research. Here we present the results of DAC experiments which allowed extending calibration curves of the fluorescence frequency versus pressure up to 120 GPa at high temperatures up to 700 K for both for ruby and Sm:YAG. Cubic boron nitride was used as the reference gauge.
On the main channel length‐area relationship for channel networks

Motivated by the empirical relationship between the main channel length and the basin area for river networks, a similar equation is derived analytically using the random model postulates and the additional assumption that link lengths have a common exponential probability distribution. Specifically, it is shown that in networks with large magnitude m, the main channel length l(m), and the magnitude are related by l(m) ∼ β(2π)½(2π)½, where β is mean link length. This result is utilized to explain another empirical relationship between the distance to the center of gravity lc(m) and the main channel length; lc(m) ∼ l(m)/2. The observed deviations of the random model prediction regarding the main channel length from empirical observations is used to discuss some important open problems.
The Millimeter- and Submillimeter-wave Spectrum of Methyl Formate (HCOOCH3)

Methyl formate (HCOOCH3), a threefold internal rotor, is a well-known interstellar molecule located in hot cores of giant molecular clouds. Over a decade ago, we published separate analyses of the rotational-torsional spectra of methyl formate in its A and E ground torsional substates. The analysis of the A substate was undertaken with a standard asymmetric top Hamiltonian, while that of the E substate was undertaken with a principal axis method (PAM), which was less than entirely satisfactory. In the interim, we have measured many new lines of the rotational-torsional spectrum of both the ground A and E torsional substates of this species through the rotational quantum number J = 50 using two spectrometers: our standard klystron-based system and a new fast scan spectrometer (FASSST). The newly measured lines have been combined with previous data to form a data set consisting of over 2000 lines that has been fitted to the accuracy of our experiments using a modification of the internal axis method (IAM) we have previously applied to methanol. The spectral constants obtained from the fit have allowed us to predict the frequencies of many additional lines up to 700 GHz in frequency and up to J = 50 in rotational quantum number.
Knockdown of CYP9A9 increases the susceptibility to lufenuron, methoxyfenozide and a mixture of both in Spodoptera exigua

Lufenuron (LUF) and Methoxyfenozide (MET) as Insect Growth Regulators (IGRs) contribute to the current control of the catastrophic crop pest, Spodoptera exigua (Lepidoptera, Noctuidae). Yet S. exigua has evolved resistance to LUF and MET, which is possibly mediated by cytochrome P450 monooxygenases (P450s), particularly from the CYP3 clade family, as it plays a key role in the detoxification of insecticides. However, a mixture of LUF and MET (MML) (optimal ratio: 6:4) remains highly insecticidal. Here, we analysed the response of S. exigua to sublethal concentrations of LUF, MET, and MML via transcriptomics. Twelve differentially expressed genes (DEGs) encoding CYP3 clade members were observed in transcriptomes and CYP9A9 was significantly upregulated after treatment with LUF, MET, and MML. Further, CYP9A9 was most highly expressed in the midgut of L4 S. exigua larvae. RNAi‐mediated knockdown of CYP9A9 reduced the activity of CYP450 and increased the susceptibility of S. exigua larvae to LUF, MET, and MML. Thus, CYP9A9 plays a key role in the detoxification of LUF, MET, and MML in S. exigua. These findings provide new insights into insecticidal actions of IGRs, which can be applied to the establishment of novel pest management strategies.
Effects of Game Weekly Frequency on Subjective Training Load, Wellness, and Injury Rate in Male Elite Soccer Players

To compare the effects of playing one or two games per week on subjective perceived exertion (RPE) and (RPE-based) training load, monotony index, sleep, stress, fatigue, and muscle soreness (Hooper index), total mood disturbance, and injury rate in elite soccer players. Fourteen males from a first-division soccer club (age: 24.42 ± 4.80 years) competed in two games per week for six weeks and one game per week for twelve weeks (a total of 24 games). Paired t-tests and non-parametric Wilcoxon signed ranks evaluated the significance of the differences (p < 0.05). The main findings were that RPE was significantly larger when playing two games per week compared with one game. However, subject total and mean training load, mood disturbance, monotony, and subjective perception of sleep, stress, fatigue, muscle soreness monitoring (Hooper index), and the number of injuries were not different. The findings suggested that competing in two matches per week does not negatively influence injury rate and players’ perceptions of training load or wellness, even though players perceive two games per week as more physically demanding compared with one game per week.
Resistance to the African Trypanosomes Is IFN-γ Dependent

The role of variant surface glycoprotein (VSG)-specific Th cell responses in determining resistance to the African trypanosomes was examined by comparing Th cell responses in relatively resistant and susceptible mice as well as in cytokine gene knockout mice infected with Trypanosoma brucei rhodesiense. Resistant B10.BR and C57BL/6 mice expressed Th1 cell cytokine responses to VSG stimulation during infection, while susceptible C3H mice produced weak or no Th1 cell cytokine responses. Neither resistant B10.BR and C57BL/6 mice nor susceptible C3H mice made detectable Th2 cell cytokine responses to parasite Ag. To more closely examine the potential role of IFN-γ and other cytokines in host resistance, we determined the resistance phenotypes and Th cell responses of IFN-γ and IL-4 knockout mice. Infected C57BL/6-IFN-γ knockout mice were as susceptible as C57BL/6-scid mice and made an IL-2, but not an IL-4, cytokine response to VSG, while C57BL/6-IL-4 knockout mice were as resistant as the wild-type strain and exhibited both IL-2 and IFN-γ cytokine responses. Passive transfer of spleen cells from wild-type mice to IFN-γ knockout mice resulted in enhanced survival. Both wild-type and IFN-γ knockout mice controlled parasitemia with VSG-specific Ab responses, although parasitemias were higher in the IFN-γ knockout mice. Overall, this study demonstrates for the first time that relative resistance to African trypanosomes is associated with a strong Th1 cell response to parasite Ags, that IFN-γ, but not IL-4, is linked to host resistance, and that susceptible animals do not make compensatory Th2 cell responses in the absence of Th1 cell cytokine responses.
Do Simulated Teaching Experiences Impact Elementary Preservice Teachers’ Ability to Facilitate Argumentation-Focused Discussions in Mathematics and Science?

Recently scholars have advocated for using teachers’ practice as a site for teacher learning. The recent proliferation of online, digital spaces, including simulated classrooms, has paved the way for novel approaches within practice-based teacher education. Yet, limited research has investigated the extent to which and how the use of online, simulated teaching experiences promote teacher learning of core teaching practices. The purpose of this study was to examine whether and how integrating simulated teaching experiences into teacher education coursework impacts preservice teacher (PST) learning. Findings showed that the use of simulated teaching experiences within elementary teacher education methods courses resulted in evidence of statistically significant growth in PSTs’ ability to engage in one core teaching practice: facilitating argumentation-focused discussions.
Prognostic Value of Pre-Treatment [18F]FDG PET/CT Texture Analysis in Undifferentiated Soft-Tissue Sarcoma

Background: Undifferentiated soft-tissue sarcomas (USTS) are one of the most common sarcoma histotypes in adults. The standard of care is surgical excision plus adjuvant radiotherapy, while the use of perioperative chemotherapy is still controversial. The aim of this study was to investigate the value of pre-treatment [18F]FDG PET/CT conventional metrics and textural features in predicting disease-free survival (DFS) and overall survival (OS) in patients with USTS of the limbs and trunk. Methods: [18F]FDG PET/CT scans of 51 consecutive patients with locally advanced USTS were retrospectively evaluated. Conventional and textural PET parameters were analysed and tested as predictive factors for DFS and OS. Results: During a median follow up of 50.7 months, 23 (45.1%) and 29 (56.9%) patients had death or disease progression, respectively. Univariate analysis revealed a significant association for perioperative treatment, PET volumetric parameters and the textural feature GLCM_correlation with DFS and OS. In multivariate analysis, perioperative treatment and GLCM_correlation were the only independent factors, allowing stratification of the population into three different prognostic classes. Conclusion: GLCM_correlation can identify USTS at high risk of relapse and death, thus helping to optimize the perioperative treatment of patients.
The Role of Sports in the Subjective Psychological Well-Being of Hungarian Adult Population in Three Waves of the COVID-19 Pandemic

(1) Background: In this study, sport and subjective psychological well-being is investigated in three waves of the COVID-19 pandemic. (2) Methods: We have conducted three different representative sample surveys (n = 3600 altogether) on the Hungarian adult population and investigated the sample’s subjective psychological well-being with the WHO-5 Well-Being Index, as well as changes in their subjective well-being through the different waves of the pandemic. Sporting habits and socio-economic variables were also surveyed, and OLS regression models were created focused on the WHO-5 measures. (3) Results: The subjective psychological well-being of the Hungarian adult population decreased significantly, but in the second and third wave of pandemic restrictions, an increase in subjective psychological well-being has been measured. The relationships between the time spent on doing sports and subjective psychological well-being were significant in each pandemic waves. The highest subjective psychological well-being and its highest increase were reported by those who could increase their time spent on doing sports as well. (4) Conclusions: The relationships between the sports activities, physical health, size of settlement, changes in income and subjective psychological well-being of the Hungarian adult population were significant in all three waves of the COVID-19 pandemic.
Influence of organo-chemical fertilizer mixed with hormones on yield of Zea mays (L.) and soil productivity

The effect of five fertilizers; NPK (15-15-15), organo-chemical hormone mixed formula 1 (HO-1), Formula 2 (HO-2), Formula 3 (HO-3) and granular organic fertilizer (GOF) were investigated on maize yield and soil properties in a Randomized Complete Block Design with 4 replications. The new hybrid maize (GT 822) was sown at 75 x 25 cm² spacing. The fertilizer rate was 300 kg ha-1. Initial soil analysis showed that the soil had a lower rate of nutrients but after the second season of trial a significant (p ≤ 0.05) improvement was observed in soil properties, the highest residual NPK of 0.875 %, 0.0275 %, and 0.0267 % were recorded in HO-3 plots. Vegetative data showed that maize height, dry matter, leaf area, and leaf chlorophyll of 270.85 cm, 282.66 g, 156.02 dm², and 56.70, respectively were also highest in HO-3 fertilizer. Plant growth indices; RGR, LAI, and dry matter use efficiency of 0.132 g g-1day-1, 5.90 and 34.4 %, respectively were best in HO-3. Grain yield and crude protein of 8276.68 kg ha-1 and 8.99 % were recorded in HO-3, followed by HO-2 and NPK. Lower yields were obtained from the control and GOF. Our finding revealed that the integration of nutrient sources in a balanced ratio produced the greatest yield output, improved soil properties, and is therefore the future approach to planning an effective fertilizer strategy. Reliance on GOF as a sole fertility package for maize production may result in significant yield losses compared to the integrated approach or use of NPK fertilizer.
The accelerating rotation of the magnetic He-weak star HD 142990

HD 142990 (V 913 Sco; B5 V) is a He-weak star with a strong surface magnetic field and a short rotation period (Prot ∼ 1 d). Whilst it is clearly a rapid rotator, recent determinations of Prot are in formal disagreement. In this paper, we collect magnetic and photometric data with a combined 40-yr baseline in order to re-evaluate Prot and examine its stability. Both period analysis of individual data sets and O − C analysis of the photometric data demonstrate that Prot has decreased over the past 30 yr, violating expectations from magnetospheric braking models, but consistent with behaviour reported for 2 other hot, rapidly rotating magnetic stars, CU Vir and HD 37776. The available magnetic and photometric time series for HD 142990 can be coherently phased assuming a spin-up rate $\dot{P}$ of approximately −0.6 s yr−1, although there is some indication that $\dot{P}$ may have slowed in recent years, possibly indicating an irregular or cyclic rotational evolution.
Sonographic peripheral nerve cross‐sectional area in adults, excluding median and ulnar nerves: A systematic review and meta‐analysis

Although electromyography remains the “gold standard” for assessing and diagnosing peripheral nerve disorders, ultrasound has emerged as a useful adjunct, providing valuable anatomic information. The objective of this study was to conduct a systematic review and meta‐analysis evaluating the normative sonographic values for adult peripheral nerve cross‐sectional area (CSA).
STUDENTS’ PERCEPTION OF DIGITAL BANKING WITH SPECIAL REFERENCE TO HIGHER EDUCATION INSTITUTIONS IN AHMEDABAD

The fast growth of the digital banking sector needs a higher level of customer satisfaction. This study sample data was taken as a convenient sampling technique with a standardized questionnaire. The digital banking dimension had (0.908) reliability, customers’ satisfaction had (0.845), reducing waiting time variable had (0.729) reliability. The sample consisted (of 254) students of Ahmedabad city of both genders. The quantitative data was analyzed with SPSS by applying Pearson correlation and t-test to understand the relationship and difference between the gender levels of satisfaction. The result statistically proved that the gender of the participants did not have any significant difference in digital banking satisfaction levels. Moreover, the Person correlations proved that there was a significant association between the levels of customers’ satisfaction with service charges, reducing waiting time, and overall digital banking.
The Effect of Digital Transformation on the Pharmaceutical Sustainable Supply Chain Performance: The Mediating Role of Information Sharing and Traceability Using Structural Equation Modeling

As the global pharmaceutical market continues to expand, the demand for pharmaceutical supply chain is increasing. In the context of “Industry 4.0”, the pharmaceutical supply chain sector needs to accelerate digital construction. Pharmaceutical companies need to strengthen risk management in order to cope with supply disruptions. From the perspective of sustainable development, the pharmaceutical supply chain can achieve sustainable supply performance in social, economic and environmental dimensions through digital transformation. There is a lack of research on digital transformation of pharmaceutical supply chain management. Further research is needed on what specific digital management pharmaceutical companies need to enhance to improve supply performance. This study uses empirical analysis to examine the impact of digital transformation on sustainable supply chain performance and to explore the role of information sharing and traceability as mediators. The aim is to guide the pharmaceutical supply chain to clearly manage the development of digital transformation and obtain sustainable supply performance. This study presents hypotheses based on cutting-edge theoretical findings. In total, 298 Chinese pharmaceutical company supply chain managers were surveyed and Structural equation analysis was conducted using SPSS26.0 and AMOS24.0. The results show that digital transformation significantly and positively impacts sustainable supply chain performance. Traceability plays a mediating role. The mediating role of information sharing is not significant. However, information sharing and traceability as two separate trends can have synergistic effects that together affect sustainable supply performance. The conclusion is that the pharmaceutical supply chain should accelerate digital construction, eliminate the uneven development of digital technology among supply chain members, and reduce the impact of technological uncertainty on performance. Companies are enhancing supply chain security management through information sharing and traceability systems, and are continuously focusing on the role of digital transformation as a driver for sustainable development.