Miracle-dz/UniFAR-FTUs huggingface dataset:
PENGARUH UKURAN PERUSAHAAN DAN LEVERAGE TERHADAP NILAI PERUSAHAAN DENGAN PROFITABILITAS SEBAGAI VARIABEL MEDIASI

Nilai perusahaan dijadikan sebagai suatu ukuran keberhasilan manajemen perusahaan dalam prospek operasi di masa mendatang sehingga dapat mewujudkan kepercayaan bagi pemegang saham perusahaan, karena apabila kesejahteraan para pemegang saham sudah mampu terpenuhi, maka sudah pasti keadaan tersebut mencerminkan nilai perusahaan yang tinggi pula. Nilai Perusahaan dapat dipengaruhi oleh beberapa faktor, antara lain yaitu Ukuran Perusahaan, Leverage dan Profitabilitas. Tujuan penelitian ini yaitu untuk mengetahui signifikansi pengaruh Ukuran Perusahaan, Leverage dan Profitabilitas terhadap Nilai Perusahaan serta untuk mengetahui signifikansi pengaruh Ukuran Perusahaan dan Leverage terhadap Profitabilitas. Metode pengumpulan data yang digunakan adalah metode observasi non partisipan dengan teknik analisis jalur ( path analysis ). Berdasarkan hasil analisis yang telah dilakukan diperoleh bahwa Ukuran Perusahaan, Leverage dan Profitabilitas berpengaruh positif signifikan terhadap Nilai Perusahaan. Ukuran Perusahaan dan Leverage berpengaruh positif signifikan terhadap Profitabilitas. Namun profitabilitas tidak mampu memediasi pengaruh Ukuran Perusahaan terhadap Nilai Perusahaan serta Profitabilitas tidak mampu memediasi pengaruh Leverage terhadap Nilai Perusahaan.
Evaluation of Some Phytochemicals in Raw and Cooked Ipomea batatas ( Lam ) , ( Sweet Potato ) , Solanum tuberosum ( Irish Potato ) and Dioscorea cayenensis ( Yellow Yam )

Cooking induces numerous phytochemical changes in food. This study is aimed at determining the amount of phytochemicals present in raw and cooked sweet potato, Irish potato and yellow yam. The amount of tannin, alkaloids, saponin, flavonoids and phenol were determined in raw and cooked samples of each food crop. The result showed that tannin, alkaloids, saponin, flavonoids, phenol contents was high in Irish potato and sweet potato but was far much present in Irish potato, while it was seen in minute quantity in yellow yam. The values obtained for each phytochemicals in each food sample raw and cooked respectively, in mg/100g were; Yellow yam: Tannins (0.10 and Nil), Alkaloids (2.00 and 0.51), Flavonoids (1.18 and 0.87), Saponins (2.00 and 1.02) and Phenols (0.72 and 0.10). Sweet potato: Tannins (0.32 and 0.28), Alkaloids (2.17 and 0.62), Saponins (2.10 and1.58), Flavonoids (1.28 and 0.97) and Phenols (1.42 and 0.72). Irish potato: Tannins (0.55 and 0.49), Alkaloids (2.17 and 0.81), Saponins (4.00 and 2.13), Flavonoids (5.00 and 2.91) and Phenols (2.00 and 0.91). The % loss of phytochemicals after cooking were; Yellow yam: Tannins (Nil), Alkaloids (74.5), Saponins (49.0), Flavonoids (26.3) and Phenols (86.1). Sweet potato: Tannins (12.5), Alkaloids (71.4), Saponins (24.8), Flavonoids (24.2) and Phenols (49.3). Irish potato: Tannins (10.0), Alkaloids (62.7), Saponins (46.8), Flavonoids (41.8) and Phenols (54.5). These results indicate that boiling of the samples seems to reduce their phytochemical contents as the raw samples showed higher amounts of the phytochemicals. The results also revealed that Tannins are more stable to heat across the 3 food samples, followed by Flavonoids, Saponins, Phenols and Alkaloids. The loss in some of the phytochemicals after cooking did not significantly affect the nutritional quality of the food samples. DOI:https://dx.doi. org/10.4314/jasem.v25i9. 3 Copyright: Copyright © 2021 Akpe et al. This is an open access article distributed under the Creative Commons Attribution License (CCL), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Dates: Received: 09 May 2021; Revised: 12 August 2021; Accepted: 12September 2021
Using machine learning to predict optimal electromagnetic induction instrument configurations for characterizing the shallow subsurface

Abstract. Electromagnetic induction (EMI) is used widely for hydrological and other environmental studies. The apparent electrical conductivity (ECa), which can be mapped efficiently with EMI, correlates with a variety of important soil attributes. EMI instruments exist with several configurations of coil spacing, orientation, and height. There are general, rule-of-thumb guides to choose an optimal instrument configuration for a specific survey. The goal of this study was to provide a robust and efficient way to design this optimization task. In this investigation, we used machine learning (ML) as an efficient tool for interpolating among the results of many forward model runs. Specifically, we generated an ensemble of 100 000 EMI forward models representing the responses of many EMI configurations to a range of three-layer subsurface models. We split the results into training and testing subsets and trained a decision tree (DT) with gradient boosting (GB) to predict the subsurface properties (layer thicknesses and EC values). We further examined the value of prior knowledge that could limit the ranges of some of the soil model parameters. We made use of the intrinsic feature importance measures of machine learning algorithms to identify optimal EMI designs for specific subsurface parameters. The optimal designs identified using this approach agreed with those that are generally recognized as optimal by informed experts for standard survey goals, giving confidence in the ML-based approach. The approach also offered insight that would be difficult, if not impossible, to offer based on rule-of-thumb optimization. We contend that such ML-informed design approaches could be applied broadly to other survey design challenges.
Multiparametric analysis of blood parameters and hyperketonemia in cows

www.afc. kg.ac. rs Multiparametric analysis of blood parameters and hyperketonemia in cows Marko R. Cincović1*, Biljana Delić Vujanović1, Radojica Đoković2, Branislava Belić1, Bojan Blond1, Siniša Grubač1, Srđan Krnjaić1, Mira Majkić1 1University of Novi Sad, Faculty of Agriculture, Department of Veterinary Medicine, Laboratory of Pathophysiology; Trg Dositeja Obradovića 8, 21000 Novi Sad, Serbia 2Faculty of Agronomy Čačak, University of Kragujevac, Cara Dušana 34, 32000 Čačak, Serbia
Potential uses of AI for perioperative nursing handoffs: a qualitative study

Objective: Situational awareness and anticipatory guidance for nurses receiving a patient after surgery are key to patient safety. Little work has defined the role of artificial intelligence (AI) to support these functions during nursing handoff communication or patient assessment. We used interviews and direct observations to better understand how AI could work in this context. Materials and Methods: 58 handoffs were observed of patients entering and leaving the post-anesthesia care unit at a single center. 11 nurses participated in semi-structured interviews. Mixed inductive-deductive thematic analysis extracted major themes and subthemes around roles for AI supporting postoperative nursing. Results: Four themes emerged from the interviews: (1) Nurse understanding of patient condition guides care decisions, (2) Handoffs are important to nurse situational awareness; problem focus and information transfer may be improved by AI, (3) AI may augment nurse care decision making and team communication, (4) User experience and information overload are likely barriers to using AI. Key subthemes included that AI-identified problems would be discussed at handoff and team communications, that AI-estimated elevated risks would trigger patient re-evaluation, and that AI-identified important data may be a valuable addition to nursing assessment. Discussion and Conclusion: Most research on postoperative handoff communication relies on structured checklists. Our results suggest that properly designed AI tools might facilitate postoperative handoff communication for nurses by identifying elevated risks faced by a specific patient, triggering discussion on those topics.
It is about who you know (and how you help them): Insights from staff and donors about how to recruit and retain a panel of committed anti‐D donors

Maintaining a panel of committed anti‐D donors is crucial for the production of anti‐D immunoglobulin to prevent haemolytic disease of the foetus and newborn. Given low numbers of donors in the Australian panel, there is a need to better understand motivators and barriers specific to anti‐D donors.
Esophageal varices in dogs: A retrospective case series

Abstract Background Esophageal varices (EV) are abnormally dilated veins in the esophagus caused by alterations of blood flow or pressure. Esophageal variceal hemorrhage is a major complication of hepatic disease in humans, but a lack of information exists regarding associated adverse events in dogs. Objective To describe the clinical manifestations and associated etiologies and outcomes of dogs with EV. Animals Twenty‐five client‐owned dogs with EV diagnosed via computed tomography (CT), endoscopy, or fluoroscopy. Methods Retrospective case series. Cases were identified by review of the hospital imaging records database between 2010 and 2020. Signalment, clinical signs, and outcomes were documented. When present, additional collateral vasculature was also recorded. Cases were subcategorized into suspected etiology based upon the anatomic location or absence of an attributable underlying disease process, as well as the direction of blood flow. Results Twenty‐four of 25 cases were identified via CT, with a prevalence of 0.012% (24/1950 total studies). Presenting clinical signs were nonspecific, and more likely because of the underlying cause as opposed to complications secondary to EV themselves. Etiologic anatomic locations were similar in occurrence between the abdomen (N = 14) and thorax (N = 11). All cases with an abdominal etiologic location had presumed or confirmed portal hypertension and 9/11 cases with a thoracic etiologic location had pulmonary, caval, or systemic hypertension. No cases died or were euthanized as a direct result of EV or associated hemorrhage. Conclusions and Clinical Importance Esophageal varices are rarely reported in dogs and commonly identified concurrently with portal, pulmonary, and caval hypertension. Hemorrhage is not a common clinical manifestation of EV.
New insights into aging-associated characteristics of female subcutaneous adipose tissue through integrative analysis of multi-omics data

ABSTRACT Aging could be critical in limiting the application of subcutaneous adipose tissue (SAT) in tissue repair and reconstruction. However, no systematic study on the characteristics of SAT aging has been conducted. In this study, a scanning electronic microscope was used to detect the structural and compositional changes of SAT collected from nine females in three age groups. Multi-omics data of SAT from 37 females were obtained from Gene Expression Omnibus database, and 1860 genes, 56 miRNAs, and 332 methylated genes were identified as being differentially expressed during aging among non-obese females. Using Weighted Correlation Network Analysis (WGCNA), 1754 DEGs were defined as aging-associated genes for non-obese females, distributed among ten co-expression modules. Through Gene Ontology enrichment analysis and Gene Set enrichment analysis on those aging-associated DEGs, SAT aging was observed to be characterized by variations in immune and inflammatory states, mitochondria, lipid and carbohydrate metabolism, and regulation of vascular development. SUPV3L1, OGT, and ARPC1B were identified as conserved and core SAT-aging-related genes, as verified by RT-qPCR among 18 samples in different age groups. Multi-omics regulatory networks of core aging-associated biological processes of SAT were also constructed. Based on WGCNA, we performed differential co-expression analysis to unveil the differences in aging-related co-expression patterns between obese and non-obese females and determined that obesity could be an important accelerating factor in aging processes. Our work provides a landscape of SAT aging, which could be helpful for further research in fields such as repair and reconstruction as well as aging.
ACTIONS OF MONOIDAL CATEGORIES AND REPRESENTATIONS OF CARTAN TYPE LIE ALGEBRAS

Abstract Using crossed homomorphisms, we show that the category of weak representations (respectively admissible representations) of Lie–Rinehart algebras (respectively Leibniz pairs) is a left module category over the monoidal category of representations of Lie algebras. In particular, the corresponding bifunctor of monoidal categories is established to give new weak representations (respectively admissible representations) of Lie–Rinehart algebras (respectively Leibniz pairs). This generalises and unifies various existing constructions of representations of many Lie algebras by using this new bifunctor. We construct some crossed homomorphisms in different situations and use our actions of monoidal categories to recover some known constructions of representations of various Lie algebras and to obtain new representations for generalised Witt algebras and their Lie subalgebras. The cohomology theory of crossed homomorphisms between Lie algebras is introduced and used to study linear deformations of crossed homomorphisms.
Trajectory curves of post-COVID anxiety/depressive symptoms and sleep quality in previously hospitalized COVID-19 survivors: the LONG-COVID-EXP-CM multicenter study

The corona virus disease 2019 (COVID-19) outbreak has increased the prevalence of depres-sive/anxiety symptoms (Oh et al., 2021). The presence of anxiety and depressive symptoms is up to 56.3% and 39.3% in hospitalized patients by COVID-19 (Li et al., 2021). Furthermore, anxiety/depressive symptoms and sleep disorders are also present at a post-COVID phase (Shanbehzadeh, Tavahomi, Zanjari, Ebrahimi-Takamjani, & Amiri-Arimi, 2021). Most studies assessing post-COVID anxiety/depressive
Lifting trianguline Galois representations along isogenies

Given a central isogeny π : G → H of connected reductive Qp-groups, and a local Galois representation ρ valued in H(Qp) that is trianguline in the sense of Daruvar, we study whether a lift of ρ along π is still trianguline. We give a positive answer under weak conditions on the Hodge–Tate–Sen weights of ρ, and the assumption that the trianguline parameter of ρ can be lifted along π. This is an analogue of the results proved by Wintenberger, Conrad, Patrikis, and Hoang Duc for p-adic Hodge-theoretic properties of ρ. We describe a Tannakian framework for all such lifting problems, and we reinterpret the existence of a lift with prescribed local properties in terms of the simple connectedness of a certain pro-semisimple group. While applying this formalism to the case of trianguline representations, we extend a result of Berger and Di Matteo on triangulable tensor products of B-pairs.
Association of Metformin with Risk of Venous Thromboembolism in Adults with Type 2 Diabetes: A General Population-Based Cohort Study.

Metformin is hypothesized to have a beneficial effect on venous thromboembolism (VTE); however, there is a paucity of data supporting this hypothesis. Among individuals aged 40-90 years with a diagnosis of type 2 diabetes in the Health Improvement Network database (2000-2019), we compared the risk of incident VTE, pulmonary embolism (PE), and deep vein thrombosis (DVT) among metformin initiators with that among sulfonylureas initiators. Individuals were followed from their first refill prescription until an incident VTE, drug discontinuation, switching or augmenting, plan disenrollment, or the end of the study, whichever occurred first. Hazard ratios (HRs), and 95% confidence intervals (CIs) were estimated using the Cox model adjusting for confounders using inverse probability of treatment weighting. Among 117,472 initiators of metformin and 13,835 initiators of sulfonylurea 555 (1.3/1000 person-years) and 75 (2.1/1000 person-years) VTE cases occurred in each group, respectively. The multivariable-adjusted HR was 0.65 (95%CI: 0.51-0.84). The corresponding risks for PE (adjusted HR=0.71, 95%CI: 0.50-1.01) and DVT (adjusted HR=0.64, 95%CI: 0.48-0.87) were also lower in metformin initiators than in sulfonylurea initiators. Our study provided empirical evidence to support a lower risk of VTE after initiation of metformin compared with sulfonylureas in patients with type 2 diabetes.
Curable sexually transmitted infections among women with HIV in sub-Saharan Africa

Objectives: Sexually transmitted infections (STIs) cause significant morbidity among women with HIV and increase HIV transmission. We estimated the prevalence of four STIs among women with HIV in sub-Saharan Africa (SSA) and compared prevalence among women with and without HIV. Design: Systematic review and meta-analysis. Methods: We searched for studies published 1 January 1999 to 19 December 2019 reporting prevalence of gonorrhea, chlamydia, trichomoniasis, or Mycoplasma genitalium among women with HIV in SSA. We excluded studies conducted in high-risk groups (e.g. female sex workers). We extracted data on laboratory-confirmed STIs among women with HIV, and when included, among women without HIV. We estimated pooled prevalence for each STI among women with HIV using inverse variance heterogeneity meta-analysis, compared prevalence to women without HIV, and examined the influences of region, clinical setting, and pregnancy status in subgroup analyses. Results: We identified 3756 unique records; 67 studies were included in the meta-analysis. Prevalence of gonorrhea, chlamydia, trichomoniasis, and M. genitalium was 3.5, 4, 15.6, and 10.2%, respectively. Chlamydia prevalence was lower in Eastern (2.8%) than in Southern (12.5%) and West/Central (19.1%) Africa combined. Prevalence of chlamydia and trichomoniasis was higher among pregnant (8.1%, 17.6%) than nonpregnant (1.7%, 12.3%) women. All STIs were more prevalent among women with than without HIV (relative risks ranging 1.54–1.89). Conclusion: STIs are common among women with HIV in SSA, and more common among women with than without HIV. Integrated STI and HIV care could substantially impact STI burden among women with HIV, with potential downstream impacts on HIV transmission.
Rethinking Social Relationships in Adulthood: The Differential Investment of Resources Model

Empirical evidence about the development of social relationships across adulthood into late life continues to accumulate, but theoretical development has lagged behind. The Differential Investment of Resources (DIRe) model integrates these empirical advances. The model defines the investment of time and energy into social ties varying in terms of emotional closeness and kinship as the core mechanism explaining the formation and maintenance of social networks. Individual characteristics, acting as capacities, motivations, and skills, determine the amount, direction, and efficacy of the investment. The context (e.g., the living situation) affects the social opportunity structure, the amount of time and energy available, and individual characteristics. Finally, the model describes two feedback loops: (a) social capital affecting the individual’s living situation and (b) different types of ties impacting individual characteristics via social exchanges, social influences, and social evaluations. The proposed model will provide a theoretical basis for future research and hypothesis testing.
Mechanisms underlying the cooperation between loss of epithelial polarity and Notch signaling during neoplastic growth in Drosophila.

Aggressive neoplastic growth can be initiated by a limited number of genetic alterations, such as the well-established cooperation between loss of cell architecture and hyperactive signaling pathways. However, our understanding of how these different alterations interact and influence each other remains very incomplete. Using Drosophila paradigms of imaginal wing disc epithelial growth, we have monitored the changes in Notch pathway activity according to the polarity status of cells (scrib mutant). We show that the scrib mutation impacts the direct transcriptional output of the Notch pathway, without altering the global distribution of Su(H), the Notch dedicated transcription factor. The Notch-dependent neoplasms require however, the action of a group of transcription factors, similar to those previously identified for Ras/scrib neoplasm (namely AP-1, Stat92E, Ftz-F1, and bZIP factors), further suggesting the importance of this transcription factor network during neoplastic growth. Finally our work highlights some Notch/scrib specificities, in particular the role of the PAR domain containing bZIP transcription factor and Notch direct target Pdp1 for neoplastic growth.
Prehospital Drug Assisted Airway Management: An NAEMSP Position Statement and Resource Document

Abstract Airway management is a critical intervention for patients with airway compromise, respiratory failure, and cardiac arrest. Many EMS agencies use drug-assisted airway management (DAAM) - the administration of sedatives alone or in combination with neuromuscular blockers - to facilitate advanced airway placement in patients with airway compromise or impending respiratory failure who also have altered mental status, agitation, or intact protective airway reflexes. While DAAM provides several benefits including improving laryngoscopy and making insertion of endotracheal tubes and supraglottic airways easier, DAAM also carries important risks. NAEMSP recommends: DAAM is an appropriate tool for EMS clinicians in systems with clear guidelines, sufficient training, and close EMS physician oversight. DAAM should not be used in settings without adequate resources. EMS physicians should develop clinical guidelines informed by evidence and oversee the training and credentialing for safe and effective DAAM. DAAM programs should include best practices of airway management including patient selection, assessmenct and positioning, preoxygenation strategies including apneic oxygenation, monitoring and management of physiologic abnormalities, selection of medications, post-intubation analgesia and sedation, equipment selection, airway confirmation and monitoring, and rescue airway techniques. Post-DAAM airway placement must be confirmed and continually monitored with waveform capnography. EMS clinicians must have the necessary equipment and training to manage patients with failed DAAM, including bag mask ventilation, supraglottic airway devices and surgical airway approaches. Continuous quality improvement for DAAM must include assessment of individual and aggregate performance metrics. Where available for review, continuous physiologic recordings (vital signs, pulse oximetry, and capnography), audio and video recordings, and assessment of patient outcomes should be part of DAAM continuous quality improvement.