Miracle-dz/UniFAR-FTUs huggingface dataset:
Clinical decision support for intervention reduction in neonatal patients: A usability assessment

Objective This study investigated how effectively simplified cognitive walkthroughs, performed independently by four nonclinical researchers, can be used to assess the usability of clinical decision support software. It also helped illuminate the types of usability issues in clinical decision support software tools that cognitive walkthroughs can identify. Method A human factors professor and three research assistants each conducted an independent cognitive walkthrough of a web-based demonstration version of T3, a physiologic monitoring system featuring a new clinical decision support software tool called MAnagement Application (MAP). They accessed the demo on personal computers in their homes and used it to walk through several pre-specified tasks, answering three standard questions at each step. Then they met to review and prioritize the findings. Results Evaluators acknowledged several positive features including concise, helpful tooltips and an informative column in the patient overview which allows users direct (one-click) access to protocol eligibility and compliance criteria. Recommendations to improve usability include: modify the language to clarify what user actions are possible; visually indicate when eligibility flags are snoozed; and specify which protocol's data is currently being shown. Conclusion Independent, simplified cognitive walkthroughs can help ensure that clinical decision support software tools will appropriately support clinicians. Four researchers used this technique to quickly, inexpensively, and effectively assess T3's new MAP tool, which suggests positive actions, such as removing a patient from a ventilator. Results indicate that, while there is room for usability improvements, the MAP tool may help reduce clinician's cognitive load, facilitating improved care. The study also confirmed that cognitive walkthroughs identify issues that make clinical decision support software hard to learn or remember to use.
Aging and Psychological Well-Being: The Possible Role of Inhibition Skills

(1) Background: Psychological well-being (PWB) is a multidimensional construct which is a key protective factor against chronic diseases in older adults. Numerous psychological and cognitive factors can influence older people’s PWB. However, while most studies have explored the effect of general cognition, only a few investigated the role of specific cognitive functions such as the efficiency of executive functions. Thus, the present study aimed to directly explore the relationships between PWB, age, and the core executive functions (namely working memory, flexibility, and inhibition). (2) Methods: A sample of 51 healthy older adults (age range: 60–88) were enrolled and tested both for PWB (by Ryff’s psychological well-being scale) and the core executive functions (by the Digit span backward, the Trail Making Test, and the Stroop test). (3) Results: Age and inhibitory skills are negatively correlated to the personal growth subscale of the PWB scale. Moreover, a hierarchical regression analysis showed that inhibition, but not working memory and flexibility, predicted the sense of continued growth and development (personal growth) of older adults, even after controlling for age and educational levels. Limitations and implications for future research and prevention interventions are discussed.
Performance of the sFLT-1 / PLGF Ratio in the Diagnosis of Preeclampsia in Four Hospitals in Brazzaville (Republic of Congo)

Preeclampsia is a serious obstetric situation, responsible for high maternal and perinatal morbidity and mortality. Its diagnosis is clinical and biological, with confirmation either by proteinuria on the urine dipstick or by 24-hour proteinuria constituting the gold standard. Current revisions to the definition of preeclampsia tend to free themselves from reliance on proteinuria for diagnosis. They are oriented towards a broader model where the involvement of a target organ concomitant with gestational hypertension is sufficient to make the diagnosis of preeclampsia. Late positivity of proteinuria after the onset of arterial hypertension (HTA) has been reported, contrasting with the precocity of angiogenic factors such as soluble Fms tyrosine kinase type 1 (sFlt-1) and placental growth factor (PlGF). Objective. To evaluate the performance of the sFLT1/PLGF ratio in the diagnosis of preeclampsia. Methods. Cross-sectional multicenter analytical study conducted from October 17 to December 17, 2020 including hypertensive pregnant women, treated or not, with more than 20 weeks of amenorrhea. These all benefited from the Elisa assay of sFLT-1 and PlGF after carrying out the proteinuria on the urine dipstick during the consultation. Preeclampsia was defined by the double positivity of proteinuria on the urine dipstick associated with high blood pressure (Systolic blood pressure ≥ 140 mmHg and/or diastolic blood pressure ≥ 90 mmHg). SPSS software was used for statistical analysis and calculation of performance indices (Se; Sp; PPV; NPV; Youden “J” index, AUC). The p-value of the probability was considered significant for a value < 0.05. Results. Pregnant women were mostly multiparous with a median age of 31 years (24-35). Preeclampsia was noted in 69.2% of cases. sFLT-1 was significantly higher in preeclamptic pregnant women (409±18.9 vs 194.6±12.9; p<0.05). No significant difference was noted for PlGF (11.9 vs 13.6; p< 0.05). The sFlt1/PlGF ratio was higher in case of preeclampsia (39.3 vs 14.6; p< 0.05). The threshold for the sFlt-/PlGF ratio retained was 18.5 (Se=86.4%; Sp=84.6%; PPV=90.5%; NPV=78.6%; J = 0.7; AUC =0.9). Conclusion. The sFlt-1/PlGF ratio was effective in the diagnosis of preeclampsia.
π Band Folding and Interlayer Band Filling of Graphene upon Interface Potassium Intercalation

The structural and electronic properties of epitaxial monolayer graphene on SiC(0001) are examined upon potassium intercalation. Notably, the first real‐space observation via scanning tunneling microscopy of the (2 × 2) superstructure in graphene‐based thin films formed by the potassium atoms below the uppermost graphene layer is presented. Therein, additional signatures stemming from quasiparticle interference effects are found allowing investigations of the electronic bands of K‐intercalated epitaxial monolayer graphene on a local scale. Those data are compared to area‐averaged results obtained from photoelectron spectroscopy. In particular, backfolding of the graphene π bands are found as a consequence of the (2 × 2) superstructure of the K atoms with respect to the graphene lattice. This is accompanied by a strong n‐type doping effect that causes a rigid shift of the Dirac bands to higher binding energies and filling of two parabolic interlayer bands at the Γ point of the surface Brillouin zone of the graphene lattice as well. This electronic configuration is promoted by additional penetration of potassium atoms into the interspace between the SiC substrate and the buffer layer that is located between the substrate and the quasi‐freestanding graphene sheet. Consequently, the epitaxial monolayer graphene sample transforms to n‐doped epitaxial bilayer graphene upon K intercalation.
Regional Anesthetic and Analgesic Techniques for Clavicle Fractures and Clavicle Surgeries: Part 1—A Scoping Review

Objective. Clavicle fractures are common injuries potentially associated with significant perioperative pain. However, this region’s complex sensory innervation poses a challenge for regional anesthetic or analgesic (RA) techniques. We conducted this scoping review to summarize the current literature, particularly with regards to motor-sparing techniques. Methods. A scoping review was carried out in accordance with the Joanna Briggs Institute’s framework. All articles describing the use of RA for clavicle fractures or surgery were included. PubMed®, Ovid MEDLINE®, EMBASE®, Scopus®, CINAHL®, and the Cochrane database were searched without language restrictions. Results. Database searches identified 845 articles, 44 of which were included in this review, with a combined patient total of 3161. We included all peer-reviewed publications containing clinical data and summarized the findings. Conclusions. Current evidence of RA techniques in clavicle surgery is heterogeneous, with different approaches used to overcome the overlapping sensory innervation. The literature largely comprises case reports/series, with several randomized controlled trials. Intermediate cervical plexus block is the regional technique of choice for clavicle surgery, and can provide reliable surgical anesthesia when combined with an interscalene block. Cervical plexus block can provide motor-sparing analgesia following clavicle surgery. Promising alternatives include the clavipectoral block, which is a novel motor-sparing regional technique. Further studies are required to determine the efficacy and safety of various techniques.
Are Creativity and Self-Efficacy at Odds? An Exploration in Variations of Product Dissection in Engineering Education

The purpose of product dissection is to teach students how a product works and provide them with inspiration for new ideas. However, little is known about how variations in dissection activities impact creative outcomes or engineering self-efficacy (ESE) and creative self-efficacies (CSE). This is important since the goal of engineering education is to produce capable and creative engineers. The current study was, thus, developed to address this research gap through a factorial experiment. The results showed that idea development was not impacted by dissection conditions but that ESE and CSE were increased through these activities. The results also showed that higher levels of CSE and ESE had alternate effects on novel idea development indicating they are at odds in engineering education.
The Effect of Aquatic Exercise Training on Heart Rate Variability in Patients with Coronary Artery Disease

(1) Background: Aquatic exercise training is a relatively understudied exercise modality in patients with CAD; with the present study, we sought to compare the impact of short-term 14-day water- and land-based exercise training on heart rate variability (HRV). (2) Methods: We randomized 90 patients after a recent CAD event (myocardial infarction and/or revascularization within 2 months prior to inclusion) to either (i) water-based or (ii) land-based exercise training (14 days, two 30 min sessions daily), or (iii) controls. Before and after the intervention period, all participants underwent 20 min 12-channel high-resolution ECG recordings with off-line HRV analysis, including conventional linear time- and frequency-domain analysis (using the Welch method for fast-Fourier transformation), and preselected non-linear analysis (Poincaré plot-derived parameters, sample entropy, and the short-term scaling exponent α1 obtained by detrended fluctuation analysis). (3) Results: Eighty-nine patients completed the study (mean age 60 ± 8 years; 20 % women). We did not detect significant differences in baseline- or age-adjusted end-of-study HRV parameters, but aquatic exercise training was associated with a significant increase in the linear LF/HF parameter (from 2.6 [1.2–4.0] to 3.0 [2.1–5.5], p = 0.046) and the non-linear α1 parameter (from 1.2 [1.1–1.4] to 1.3 [1.2–1.5], p = 0.043). (4) Conclusions: Our results have shown that a short-term 14-day aquatic exercise training program improves selected HRV parameters, suggesting this mode of exercise is safe and may be beneficial in patients with CAD.
Stingless Bee Tetragonula iridipennis and Honey Bee Apis cerana Pollination in Cucumber

Pollination in cucumber (Cucumis sativus L.) was studied using stingless bees, Tetragonula iridipennis Smith and honey bee, Apis cerana F. Data on the resource partitioning revealed the foraging activity of pollinators. Pollination efficiency index was observed to be maximum with A. cerana (24) followed by T. iridipennis (14), and significantly maximum fruit set (81.66 and 78.97%) was obtained with their pollination. An increase of 87.48% in fruit set, 46.47% in healthy fruits and 275.23% in seed numbers was noticed, with longer (17.85 and 17.22 cm) and heavier (0.415 and 0.411 kg) fruits in the A. cerana and T. iridipennis pollinated plots. Maximum number of healthy fruits was achieved with bee pollination as compared to open pollination and control, and A. cerana showed more mortality as compared to T. iridipennis.
Stochastic models of a self regulated gene network

In this thesis, after briefly describing the usual stochastic methods for biochemical reactions, we study in-depth a simple genetic module comprising a promoter and a gene responsible for protein synthesis. The main interest of this model is the possibility for the promoter to be selfregulated, either positively or negatively. This genetic module has been widely studied in the literature. The first Markovian approach to the model goes back to Peccoud & Ycart (1995), where the authors provide an exact result in the simplest case where the promoter is not regulated, while Hornos et al. (2005) compute the invariant measure in the case of a negative linear feedback.
Enhanced PTC Effect in Polyamide/Carbon Black Composites

Self-heating nanocomposites with a positive temperature coefficient (PTC) provide outstanding potential for a broad range of engineering applications in automobile, spacecraft, or smart building. Therefore, extensive studies have been carried out to understand thermo-electrical behavior. However, some controversies remain, especially on the material composition, to clarify influencing factors on the PTC performance. In this study, the thermo-electrical behaviors of injection molded carbon black (CB)/polyamide (PA) nanocomposites have been investigated. Three types of CB with well-defined specific surface area and polyamides with high and low crystallinity were selected to provide a guideline for self-heating devices including PTC-Effects. Significantly reduced specific resistances up to 2.7 Ω·cm were achieved by incorporating CB with a high specific surface area into a highly crystalline PA. Noticeable PTC-Effects of ~53% and average surface temperatures up to 147 °C have been observed due to self-heating, which confirms a promising material performance as a heating device.
Management of Chilo partellus Swinhoe and Stenachroia elongella Hampson in midhills of Meghalaya

A field experiment was conducted at the ICAR Research Complex for NEH Region, Umiam, Meghalaya to evaluate nine pesticides applied in two phenological stages of maize (variety Vijay composite) against stem borer Chilo partellus (Swinhoe), and cob borer Stenachroia elongella Hampson. Deadheart due to stem borer recorded after 30 and 45 days after emergence and cob borer infestation recorded during harvesting of cobs revealed that flubendiamide was superior with 80.09% reduction in infestation of deadheart and 80.38% reduction of cob borer over untreated control. Similarly, among the biopesticides, Bacillus thuringiensis was effective against both the pests.
Incorporation of Different Physical Forms of Fat Replacers in the Production of Low-Fat/ Reduced-Fat Meat Products: Which is More Practical?

ABSTRACT This review details the different approaches to replacing animal fat used in meat products with non-animal fat ingredients based on their physical forms during processing. Six different physical forms to replace the fat are categorized as 1) powder, 2) paste, 3) plant oils, 4) combinations of dietary fiber with plant oils or animal protein/skin, 5) pre-treated fat replacer, and 6) oleogel and emulsion gels. The ingredients, characteristics, processes, mechanisms, advantages, and disadvantages of all the fat replacers are discussed extensively. The oleogel and emulsion gel approach is found to be the most practical by retaining the solid-like properties while possessing a healthier fatty acid profile over other approaches. This approach also can solubilize both hydrophobic and hydrophilic components and also have good thermodynamic stability, thus imitating the animal fat. In addition, the cost of production is kept low while maintaining the nutritional attributes, physicochemical and sensorial properties of meat products.
The Effects of Kefir and Kefir Components on Immune and Metabolic Physiology in Pre-Clinical Studies: A Narrative Review

Kefir, a fermented beverage made from kefir grains, has gained immense popularity around the world due to its potential health-promoting properties. Kefir beverages are both marketed commercially and brewed privately by individuals. Both milk and sugar solutions can be used as substrates with various additives included based on consumer preference. Fermentation occurs via microorganisms including lactic acid bacteria, acetic acid bacteria, and yeasts, which are naturally present in kefir grains. Health-promoting effects of kefir are thought to occur through immune, gastrointestinal, and metabolic regulation. Both clinical trials and mechanistic studies in cell culture and animal models have explored these effects. Studies in vitro and in animals have shown the ability of kefir and kefir components to antagonize pathogens, reduce proinflammatory cytokine production, contribute to cytotoxicity of tumor cell lines and reduce tumor burden, and improve serum glycemic and lipid profiles. However, some data from clinical trials are conflicting, and the precise mechanisms by which kefir promotes well-being are not completely defined. This review summarizes the current body of evidence in both cell culture and animal models that provide insight into the mechanisms by which kefir beverages may protect consumers from enteric infections and improve immune and metabolic health. We believe that readers will gain knowledge helpful for both developing more targeted mechanistic studies and selecting informative outcomes when designing clinical studies.
The complete chloroplast genome of Acer Pubipetiolatum var. pingpienense (Sapindaceae)

Abstract The genus Acer is widespread throughout the northern temperate zone, and many species within the genus are of ecological and economical importance. Here we report the newly sequenced chloroplast genome of Acer pubipetiolatum var. pingpienense. This chloroplast genome has a total length of 156,730 bp, and contains a pair of inverted repeats (IRs, 26,743 bp), a large single-copy (LSC) region of 71,582 bp and a small single-copy (SSC) region of 18,092 bp. Phylogenetic analysis suggests that A. pubipetiolatum var. pingpienense is closely related to A. laevigatum, and both fall into Section Palmata. The complete A. pubipetiolatum var. pingpienense chloroplast genome will provide an important genetic resource for future research into the conservation and evolution of this genus. Our findings also suggest that further research is necessary to elucidate the phylogenetic relationships between plant species within this genus.
Exploring tourism-generated social media communication, brand equity, satisfaction, and loyalty: A PLS-SEM-based multi-sequential approach

Although social media-based brand equity has become a vital area of interest for brand managers, insights into its destination-based dynamics and applications remain scarce, specifically in the destination brand context. To address this gap, we develop and test a theoretical model to investigate the role of destination marketing organization-generated and tourist-generated social media communication to determine the brand awareness and brand image of the Gilgit-Baltistan region, which in turn influence customer-based brand equity (CBBE) (i.e. perceived quality), satisfaction, and loyalty. Data come from well-known tourist sites in Gilgit-Baltistan. Using the multi-sequential approach in WarpPLS 7.0, findings shows that the social media communication dimensions show differential impacts on brand awareness as a metric of CBBE. Second, destination awareness demonstrates a differential impact on perceived destination image dimensions. Third, the destination image dimensions exert different effects on the perceived quality of the destination. Fourth, perceived quality positively influences satisfaction, which in turn enhances loyalty. We offer important implications that emerged from the analyzes and also suggest directions for future research.
Dielectric properties of eggshell powder at 2.45 and 5.8 GHz relevant to dielectric heating

Abstract In present studies, dielectric properties of eggshell powder were determined at microwave frequencies 2.45 and 5.8 GHz by varying temperature and moisture content in the range 15–75 °C and 0.5–8% (wet-basis) respectively, using cavity perturbation technique. Values of dielectric constant (ε′) and loss factor (ε″) increase with temperature and moisture content at both of these frequencies but ε′ is higher at 2.45 GHz than 5.8 GHz whereas ε″ shows opposite trend. The calculated penetration depths of microwaves are more at 2.45 GHz than 5.8 GHz and it decreases with increase in temperature as well as moisture content. The determined data of ε′ and ε″ were used to generate the third order regression equations with high correlation coefficients (R 2 > 0.95). These findings are useful for modelling and designing the microwave applicator for heat treatment to eggshell powder. Additionally, X-ray diffraction spectra was also recorded.
Report of Guava Fruit Fly Bactrocera correcta Bezzi from Temperate Kashmir

In this study the guava fruit fly Bactrocera correcta Bezzi (1916) (Diptera: Tephritidae) is reported fromKulgam, a major peach growing area in South Kashmir through July-August, 2020. District Kulgamwas the leading producer of peaches with an annual production of 412MT during the 2018-19 growingseason. This potential pest was trapped along with B. zonata and B. dorsalis in a simple bottle-type trapcontaining methyl eugenol and SPLAT.
Hydroxytyrosol in Foods: Analysis, Food Sources, EU Dietary Intake, and Potential Uses

Hydroxytyrosol (HT) is a phenolic compound with proven biological properties present in a limited number of foods such as table olives, virgin olive oil (VOO) and wines. The present work aims to evaluate the dietary intake of HT in the European (EU) population by compiling scattered literature data on its concentration in foods. The consumption of the involved foods was estimated based on the EFSA Comprehensive European Food Consumption Database. The updated average contents of HT are as follows: 629.1, 5.2 and 2.1 µg/g for olives, olive oil and wine, respectively. The HT estimated intake in the European Union (EU) adult population falls within 0.13–6.82 mg/day/person, with table olives and wine being the main contributors. The estimated mean dietary intake of HT in EU countries is 1.97 ± 2.62 mg/day. Greece showed the highest HT intake (6.82 mg/day), while Austria presented the lowest (0.13 mg/day). Moreover, HT is an authorized novel food ingredient in the EU that can be added to different foods. Since the estimated HT intake is substantially low, the use of HT as a food ingredient seems feasible. This opens new possibilities for revalorizing waste products from olive oil and olive production which are rich HT sources.