Miracle-dz/UniFAR-FTUs huggingface dataset:
Effect of Different Bleaching Gels Thickeners on Cytotoxicity to Human Gingival Fibroblasts and Enamel Physical Properties: an in Situ Study

Objective This study evaluated in vitro, the effects of carbamide peroxide 10% (CP) associated with Carbopol® (CP-ct) and Aristoflex® (CP-at) thickeners on human gingival fibroblasts (HGF) cytotoxicity and assessed in situ their effects on dental enamel. Material and methods The cytotoxicity was analyzed using MTT - Vybrant® proliferation test. For in situ stage, 144 bovine enamel/dentin blocks were randomized into seven groups (n=12). Samples were stained, fixed in intraoral palatal devices and bleached for 4 h, during 14 days, with: Carbopol thickener (ct), Aristoflex thickener (at), CP-ct, CP-at, CP without thickener (CP-wot), Commercial CP (CP-com). The samples had their microhardness (SMH), roughness (Ra) and color analyzed using a microdurometer, a rugosimeter and a spectrophotometer, respectively. The analyses were performed at baseline and 24-h after completion of tooth bleaching. Results Different thickeners were similar regarding their cytotoxicity. The experimental gels with Carbopol exhibited lower SMH values, while the groups treated with CP exhibited higher Ra values. For the color change results, the groups treated with CP had values above the acceptability and perceptibility limits. Conclusion CP-at was able to promote an effective bleaching with less alterations of the tooth surface compared to the CP-ct. Hence, Aristoflex stands as a promising thickener in conjunction with CP in order to preserve the physical properties of dental enamel after home bleaching.
What’s New in Cryptococcus gattii: From Bench to Bedside and Beyond

Cryptococcus species are a major cause of life-threatening infections in immunocompromised and immunocompetent hosts. While most disease is caused by Cryptococcus neoformans, Cryptococcus gattii, a genotypically and phenotypically distinct species, is responsible for 11–33% of global cases of cryptococcosis. Despite best treatment, C. gattii infections are associated with early mortality rates of 10–25%. The World Health Organization’s recently released Fungal Priority Pathogen List classified C. gattii as a medium-priority pathogen due to the lack of effective therapies and robust clinical and epidemiological data. This narrative review summarizes the latest research on the taxonomy, epidemiology, pathogenesis, laboratory testing, and management of C. gattii infections.
Characterization and morphological study of microbes in treated palm oil mill effluents

Palm oil mill effluent (POME) is wastewater generated by palm oil milling. Due to its extremely polluting qualities, it must be treated before being discharged into the water course. This study was aimed to evaluate the bacterial growth of raw and treated POME as well as identifying indigenous microorganisms by determining the morphological characteristics of bacteria that were found in the POME. The bacterial growth was identified by bacterial enumeration of colony forming units (CFU). Besides, the morphological identification of bacteria was determined by using gram staining. The results show the best bacterial growth curve is from serial dilution factor of 10-6 with a total of 2.24 x 10-6 CFU/mL in raw POME and optimum growth on day seven. While for the treated POME, the total is 1.97 x 10-6 CFU/mL and recorded the optimum growth on day ten of incubation. The growth curve indicates the number of colonies in raw POME is higher than treated POME. It concluded that treated POME still has the bacteria although it has been treated. Apart from that, from the morphological identification by gram staining, the bacteria were Bacillus cereus, Bacillus subtilis, Staphylococcus aureus and Micrococcus luteus. From a gram staining, this research obtained all gram positive in purple colour from the POME samples. Two of them in treated POME were in Bacillus shape while the other two from raw and treated POME were in coccus shape, respectively.
FAKTOR-FAKTOR YANG MEMPENGARUHI GREEN COMPETITIVE ADVANTAGE

This study aims to examine and analyze the effect of environmental organizational culture, environmental leadership, environmental capability, green innovation, green supply chain management, and green organizational culture on green competitive advantage. This study analyzes the influence between variables through hypothesis testing (causality research). The data used are secondary data from sustainability reports and/or annual reports of companies listed on the Indonesia Stock Exchange (IDX) for the period 2020-2021.There are 369 research samples that meet the predetermined criteria (purposive sampling method). Data analysis using SPSS version 22.0. The result is that environmental leadership, environmental capability, and green supply chain management have a significant positive effect on green competitive advantage, while environmental organizational culture, green innovation, and green organizational culture have no effect on green competitive advantage.
Dissipation and Cavitation Characteristics of Single-Hole Orifices

The purpose of this work is to study the dependence of the pressure losses through sharp-edged orifices with respect to the most significant parameters and to find an efficient way to check whether cavitation is likely to occur. Computational fluid dynamics was used to simulate the flow through orifices with different geometrical characteristics for various incoming flow velocities. In particular, the diameter ratio was varied between 0.39 and 0.70, the relative thickness between 0.30 and 1.40, and the pipe Reynolds number between 3.85 x 10 4 and 1.54 x 10 5 . The computed pressure drop coefficient in the region of self-similarity with respect to the pipe Reynolds number was first compared to that obtained from some literature models. Afterwards, the comparison with experimental data revealed that an extended pressure criterion is suitable to predict the presence of cavitating conditions. A dimensionless minimum pressure coefficient was then defined, and its dependence upon the above mentioned geometrical and flow parameters was investigated. Finally, a practical formula for the prediction of cavitation was provided.
Physiological prediction of masking release for normal-hearing and hearing-impaired listeners

Leger et al. [J. Acoust. Soc. Am. (2012)] measured the intelligibility of speech in steady and spectrally or temporally modulated maskers for stimuli filtered into low- (<1.5 kHz) and mid-frequency (1–3 kHz) regions. Listeners with high-frequency hearing loss but near to clinically normal audiograms in the low- and mid-frequency regions showed poorer performance than a control group with normal hearing, but showed preserved spectral and temporal masking release. Here, we investigated whether a physiologically accurate model of the auditory periphery [Zilany et al., J. Acoust. Soc. Am. (2009)] can explain these masking release data. Intelligibility was predicted using the Neurogram SIMilarity (NSIM) metric of Hines and Harte [Speech Commun. (2010) and (2012)]. This metric can make use of either an “all-information” neurogram with small time bins or a “mean-rate” neurogram with large time bins. The average audiograms of the different groups of listeners from the study of Leger et al. were simulated in the m.
Use of Multi-Scale Investigation to Evaluate Adhesion Performance of Warm-Mix Polymer-Modified Asphalt

Warm Mix Asphalt (WMA) technology can effectively reduce carbon emissions and energy consumption during road project construction. However, it may have a negative impact on the binding properties of asphalt mixtures. In order to effectively evaluate the adhesion performance of asphalt binders and aggregates under the combined influence of WMA and traditional polymer-modified asphalt, this paper provides a comprehensive evaluation at the micro and macro levels. The adhesion between three different modified asphalts (warm mix crumb rubber/ Styrene-Butadiene-Styrene (SBS) composite modified asphalt, warm mix crumb rubber asphalt, and warm mix SBS modified asphalt) and two different aggregates (limestone and granite) under both virgin and short-term aging conditions were analyzed. Regardless of the type of modified asphalt, the results showed that limestone aggregates have better adhesion properties with asphalt binders. In addition, the short-term thermal oxidation aging behavior is conducive to enhancing the asphalt-aggregate adhesion characteristics. Furthermore, WMA additives, crumb rubber, and SBS compound modification can improve the adhesion performance between asphalt and aggregate.
Mediating and Moderating Effects of Psychological Detachment on the Association Between Stressors and Depression

The clinical significance of this paper is the finding of the coexistence of the mediating and moderating effects of psychological detachment (PD) with respect to the effects of stressors on depression over long intervals. It emphasizes the importance of tailored interventions targeting stressors and PD. Objectives This study examines the mediating and moderating effects of psychological detachment (PD) based on the stressor-detachment model in the long term. Methods Two waves of Web-based surveys, 28 months apart, yielded 3556 responses from Japanese workers. Comparisons between models that included mediating and moderating effects of PD and reverse direction mediating effects (strain → PD → stressor) were made by structural equation modeling. Differences in depression as a strain between combinations of high and low stressors and PD were also examined. Results The best-fitting model was the moderation/reciprocal partial-mediation model. The effect of PD was significant in the group with stable or decreasing stressor. Conclusion According to the worker's level of stressors, PD, and depression, targeted interventions may effectively prevent physical and mental health problems caused by chronic stress.
COVID-19 Public Opinion: A Twitter Healthcare Data Processing Using Machine Learning Methodologies

The COVID-19 pandemic has shattered the whole world, and due to this, millions of people have posted their sentiments toward the pandemic on different social media platforms. This resulted in a huge information flow on social media and attracted many research studies aimed at extracting useful information to understand the sentiments. This paper analyses data imported from the Twitter API for the healthcare sector, emphasizing sub-domains, such as vaccines, post-COVID-19 health issues and healthcare service providers. The main objective of this research is to analyze machine learning models for classifying the sentiments of people and analyzing the direction of polarity by considering the views of the majority of people. The inferences drawn from this analysis may be useful for concerned authorities as they work to make appropriate policy decisions and strategic decisions. Various machine learning models were developed to extract the actual emotions, and results show that the support vector machine model outperforms with an average accuracy of 82.67% compared with the logistic regression, random forest, multinomial naïve Bayes and long short-term memory models, which present 78%, 77%, 68.67% and 75% accuracy, respectively.
Recreational experientialism at ‘the abyss’: rethinking the sustainability crisis and experimental politics

Abstract In light of mounting complexity and uncertainty, and challenged by the ever-accelerating pace of societal change, politics and policy making have become increasingly experimental. This also applies to sustainability politics and the project of a socio-ecological transformation. But can late-modern societies experiment themselves out of their sustainability crisis? Prompted by this question and seeking to contribute to a more complex understanding of experimental politics, this article first rethinks the notion of the sustainability crisis and, on that basis, then reconsiders established understandings of experimental politics. It focuses on self-proclaimed advanced-modern societies in the global North and suggests that, reaching well beyond more established readings of the term, their much-debated sustainability crisis ought to be understood as a crisis of their ideal and self-understanding as liberal, democratic open societies. As regards experimental politics, the article focuses specifically on social movement-based experimental politics which is widely regarded as a promising pathway toward a socio-ecological transformation. Yet, the conceptualization of the sustainability crisis suggested here raises questions about this interpretation. Supplementing established readings of social movement politics as transformative experimentalism, it prompts a reinterpretation as recreational experientialism: helping to cope with the transition of late-modern societies toward a modernity beyond the ideal of the open society. The article takes a mainly conceptual, social theory-oriented approach.
Outer generalized inverses with prescribed ideals

The outer inverse of a bounded linear operator on a Banach space is unique if we fix its range and nullspace. In this note we review several approaches to the uniqueness of the outer inverse in rings and explore the underlying idea of prescribing certain ideals in a way that mimics the operators case. Starting with Djordjevic and Wei -inverses, we show some connections with Mary’s inverse along an element and give a characterization of Drazin’s annihilator -inverse.
A Case Report and Literature Review of New-Onset Myasthenia Gravis After COVID-19 Infection

Myasthenia gravis (MG) is an autoimmune disorder affecting the neuromuscular junction caused by a B-cell-mediated, T-cell-dependent immunologic attack at the end plate of the postsynaptic membrane. Attack on muscle acetylcholine receptors (AChR) of the postsynaptic membrane due to the AChR, muscle-specific tyrosine kinase, or lipoprotein receptor-related peptide 4 antibodies lead to symptoms of painless, fluctuating weakness of muscle groups and often begins with ocular signs and symptoms. Coronavirus disease 2019 (COVID-19) is an acute respiratory disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a novel coronavirus closely related to SARS-CoV. Serious neurologic complications are infrequent and diverse with reported cases of stroke, encephalitis/meningitis, Guillain-Barré syndrome, acute disseminated encephalomyelitis, ataxia, and unspecified limb weakness. MG is a rarely reported sequela of COVID-19 infection. To date, there are 15 reported cases of post-COVID-19 MG. In this article, we present a case of post-COVID-19 MG and a concise review of other reported cases. An 83-year-old Caucasian male with a medical history of atrial fibrillation status post-ablation and non-ischemic cardiomyopathy was initially admitted for COVID-19 pneumonia. He was treated with remdesivir, convalescent plasma, and supplemental oxygen therapy but did not require invasive mechanical intubation. One month after discharge, he started experiencing fatigue with muscle weakness and progressive dyspnea. He progressed to develop dysphonia, especially at the end of the day. After extensive workup, he was diagnosed with MG with a positive antibody against the AChR. The chronological events of developing slowly worsening muscular weakness after recovering from COVID-19 infection and positive AChR antibody led to the diagnosis of post-COVID-19 new-onset MG. Post-COVID-19 fatigue, long-term use of steroids, and intensive care unit-related physical deconditioning can be confounders in the clinical presentation of post-COVID-19 new-onset MG. Careful history-taking and meticulous assessment of chronological events are needed to diagnose this rare entity.
Trend and Variability of the Atmospheric Water Vapor: A Mean Sea Level Issue

AbstractThe wet tropospheric path delay is presently the main source of error in the estimation of the mean sea level by satellite altimetry. This correction on altimetric measurements, provided by a dedicated radiometer aboard the satellite, directly depends on the atmospheric water vapor content. Nowadays, water vapor products from microwave radiometers are rather consistent but important discrepancies remain. Understanding these differences can help improve the retrieval of water vapor and reduce at the same time the error on the mean sea level.Three radiometers are compared: the Advanced Microwave Scanning Radiometer for Earth Observing System (AMSR-E), Jason-1 microwave radiometer (JMR), and Envisat microwave radiometer (MWR). Water vapor products are analyzed both in terms of spatial and temporal distribution over the period 2004–10, using AMSR-E as a reference. The Interim ECMWF Re-Analysis (ERA-Interim) data are also included in the study as an additional point of comparison. Overall, the study co.
Assessing groundwater potential in Foumban and implication on urban planning in the context of sustainable development

Abstract Water stress is an everyday issue in developing countries and especially in Foumban, a municipality located in the West Region of Cameroon between longitudes 10°40’-11°10’E and latitudes 05°30’-05°55’N. The failure of the water distribution system in the Municipality of Foumban (MoF) led the citizens as well as the municipal authorities to exploit groundwater. Unfortunately, an extensive hydrogeophysical field campaign, with incidental cost, is required because the groundwater potential is not priorly assessed. The main objective of this article is to demarcate groundwater potential zones of MoF. For this, six thematic layers contributing to groundwater occurrences are combined using analytical hierarchy process (AHP) on a GIS environment to produce a sound groundwater potential map. This map is classified into three zones: low potential for 39.06%, acceptable potential for 27.27% and high potential for 33.68% of the study area. This may help to increase the rate of productive wells (by focusing hydrogeophysical investigation on areas with high groundwater potential) using little financial resources.
Fecal and gastric fluid microbiome profiles in the indopacific bottlenose dolphins (Tursiops aduncus)

The microbiota of the gastrointestinal system of dolphins has received significant interest recently. Moreover, little is understood about the microbiomes found in the stomachs of Indo-Pacific bottlenose dolphins ( Tursiops aduncus ). This study aimed to evaluate the biodiversity of bacterial microbiota in the digestive system of T. aduncus . In the present study, 18 samples were obtained from an ex-situ conservation area, Wersut Seguni Indonesia, Kendal, Indonesia, and processed for bacterial DNA extraction. A total of 7 samples were qualified as representative samples for the 16S metagenomic sequencing. The bacterial composition revealed that the Shewanellaceae was significantly higher in the stomach than in the gut. As a result, the abundance of the microbiome in gastric and stool samples showed significant differences. In contrast, the Peptostreptococcaceae was found in greater abundance in the gut than in the stomach. At the species level, we successfully found emerging zoonotic pathogens involving Shewanella algae and Shewanella xiamenensis . This report is the first study to explore the bacterial diversity in gastro of T. aduncus .
The seesaw in winter temperatures between Greenland and Northern Europe. Part II: Some oceanic and atmospheric effects in middle and high latitudes

Abstract Description of the seesaw in wintertime climate between Greenland and northern Europe is continued in terms of variations in long waves, frequencies of highs and lows, zonal geostrophic winds, precipitation, sea ice and sea surface temperatures. The monthly variations in four circulation modes are described. Significant spatial correlations exist between the zonal. component of the geostrophic wind in the area of the strongest westerlies in the North Atlantic Ocean and the zonal geostrophic wind elsewhere north of 20°N in winter. Long waves 1 and 2 change substantially from one phase of the seesaw to the other at 63°N. At 45°N only wave 2 changes appreciably between phases. Large, statisticaly significant anomalies occur during and after seesaw winters in the atmosphere-ocean-ice system of the North Atlantic Ocean and its periphery, as well as in the North Pacific Ocean. Anomalies of sea surface temperature which develop during seesaw winters tend to persist through the subsequent spring and summ.
Properties of Topological Networks of Flexible Polygonal Chains

Abstract Trypanosomatida parasites, such as Trypanosoma and Leishmania, are the cause of deadly diseases in many third world countries. The three dimensional structure of their mitochondrial DNA, known as kinetoplast DNA (kDNA), is unique since it is organized into several thousands of minicircles that are topologically linked. How and why the minicircles form such a network have remained unanswered questions. In our previous work we have presented a model of network formation that hypothesizes that the network is solely driven by the confinement of minicircles. Our model shows that upon confinement a percolation network forms. This network grows into a space filling network, called saturation network, upon further confinement of minicircles. Our model also shows, in agreement with experimental data, that the mean valence of the network (that is, the average number of minicircles topologically linked to any minicircle in the network) grows linearly with minicircle density. In our previous studies however we disregarded DNA flexibility and used rigid minicircles to model DNA, here we address this limitation by allowing minicircles to be flexible. Our numerical results show that the topological characteristics that describe the growth and topology of the minicircle networks have similar values to those observed in the case of rigid minicircles suggesting that these properties are robust and therefore a potentially adequate description of the networks observed in Trypanosomatid parasites.
Enzymatically-mineralized double-network hydrogels with ultrahigh mechanical strength, toughness, and stiffness

Background: Synthetic hydrogels are commonly mechanically weak which limits the scope of their applications. Methods: In this study, we synthesized an organic-inorganic hybrid hydrogel with ultrahigh strength, stiffness, and toughness via enzyme-induced mineralization of calcium phosphate in a double network of bacterial cellulose nanofibers and alginate-Ca2+. Results: Cellulose nanofibers formed the first rigid network via hydrogen binding and templated the deposition of calcium phosphate, while alginate-Ca2+ formed the second energy-dissipating network via ionic interaction. The two networks created a brick-mortar-like structure, in which the “tortuous fracture path” mechanism by breaking the interlaced calcium phosphate-coated bacterial cellulose nanofibers and the hysteresis by unzipping the ionic alginate-Ca2+ network made a great contribution to the mechanical properties of the hydrogels. Conclusion: The optimized hydrogel exhibited ultrahigh fracture stress of 48 MPa, Young's modulus of 1329 MPa, and fracture energy of 3013 J/m2, which are barely possessed by the reported synthetic hydrogels. Finally, the hydrogel represented potential use in subchondral bone defect repair in an ex vivo model.