Miracle-dz/UniFAR-FTUs huggingface dataset:
Optimal information extractable in a measurement

In any measurement of a parameter, effect of finite resource is manifested in a finite number ($M$) of probable values for the estimate. Here it is shown that this count of the discrete number of measurement outcomes leads to a pair of equivalent bounds:$\delta \geq 1/M$ on precision($\delta$) and $I \leq \log(M)$ on \textit{mutual information} ($I$) between the parameter and its estimate. Furthermore, the probe particle symmetry is found to play a significant role in limiting $M$ and thereby, in limiting extractable information in a measurement. In particular, for $N$ indistinguishable spin-half probe particles, it is shown that $M$ is tightly bounded to $O(N^2)$. The corresponding operator that saturates this bound represents a non interferometric measurement. While inherently Heisenberg limited, this measurement is precise up to $\delta \sim 1/N^2$. These results can be used to benchmark any precision measurement thereby establishing a particular link between information theory and metrology.
Association Serum Lipid Levels with Periodontal Disease in Korean Adults Over the Age of 50: The Korea National Health and Nutrition Examination Survey, 2016-2018

in adults over the age of 50 is rapidly increasing, the association between serum lipid levels and periodontal disease in Korean adults over the age of 50 still remains to investigate. Thus, the aim was to deter-mine the effect of serum lipid levels on periodontal disease in older adults over the age of 50 using data from the seventh Korea National Health and Nutrition Examination Survey. METHODS: The study used the data of 809 adults aged ≥50 years targeted in the 7th Korea National Health and Nutrition Examination Survey, 2016-2018. Levels of total cholesterol, triglyceride, high density- lipoprotein (HDL-cholesterol), and low density-lipopro-tein (LDL-cholesterol) and periodontal conditions were measured. Complex-sample chi square test and linear regression were used to analyze the relationship serum lipid levels with periodontal disease. RESULTS: The results of chi square tests showed that the prevalence of periodontal disease among the elderly ≥50 years were statistically significant differences according to gender, age, education level, marital status, and smoking status. After adjusting for all con-founding factors, HDL-cholesterol alleviated periodontal disease, while LDL-cholesterol exacerbates periodontal disease. However, total cholesterol and triglycerides were not connected with periodontal disease. CONCLUSIONS: Therefore, controlling HDL and LDL cholesterol levels through physical exercise could be a preventative measure for periodontal disease.
Modelling long‐term human immunodeficiency virus dynamic models with application to acquired immune deficiency syndrome clinical study

Summary. Mathematical modelling of human immunodeficiency virus (HIV) dynamics has played an important role in acquired immune deficiency syndrome research. Deterministic dynamic models have been developed to study the viral dynamic process for understanding the pathogenesis of HIV type 1 infection and antiviral treatment strategies. We propose a new multistage estimation procedure which uses data, HIV viral load and CD4+ T‐cell counts, from an acquired immune deficiency syndrome clinical study, to estimate the parameters in a long‐term HIV dynamic model containing both constant and time varying parameters. Simulation studies and a real data application show that the methods proposed are efficient and appropriate to estimate both constant and time varying parameters in long‐term HIV dynamic models.
Pure Autonomic Failure-A Localized Alpha Synucleinopathy with a Potential for Conversion to More Extensive Alpha Synucleinopathies

Pure autonomic failure (PAF) is an alpha synucleinopathy with predominant involvement of the autonomic ganglia and peripheral nerves. The hallmark clinical feature is orthostatic hypotension. However, genitourinary, sudomotor, and cardiac involvement is also common. Many patients also develop supine hypertension. Almost a quarter of patients can phenoconvert or evolve into Parkinson's disease, multiple system atrophy, and Lewy body dementia in the future. Early severe bladder involvement, higher supine noradrenaline level, early motor involvement, and dream enactment behavior increase the risk of phenoconversion. The diagnosis is confirmed via autonomic function testing and serum noradrenaline measurement. The treatment is mainly supportive. The non-pharmacological treatment includes adequate fluid, dietary salt, compression stockings, and abdominal binders. The drug therapies to improve blood pressure include midodrine, fludrocortisone, pyridostigmine, and droxidopa. The diagnostic criteria need to be updated to incorporate the recent understandings. The treatment of orthostatic hypotension and supine hypertension is mainly based on case series and anecdotal reports. Randomized control trials are needed to ascertain the best treatment strategies for PAF.
Assessing the Impacts of Economic Policy Uncertainty of the US on the Exchange Rates and Stock Returns of Korea, Mexico, Poland and Russia

ABSTRACT This study examines the effects of the economic policy uncertainty (EPU) index of the US on the exchange rates and stock returns of Korea, Mexico, Poland, and Russia. A time-varying causality test showed that the impacts of EPU of the US on the exchange and stock market of emerging countries could be affected by regime changes. A quantile regression model suggested that the effect of the increase/decrease in the EPU of the US may affect financial variables, while it was indicated that effects of the EPU of the US on the exchange rates and stock returns are asymmetrical.
The Impossible Love of Fossil Fuel Companies for Carbon Taxes

Economists agree that carbon taxes are the most effective solution for climate change mitigation. But where do fossil fuel companies stand on carbon taxes? I analyse how the 100 largest oil and gas companies communicate on carbon taxes. Surprisingly, I find that 54% of companies that have a policy view on carbon taxes support them (78% for the 50 largest). This is puzzling as an effective carbon tax should reduce revenues and reserve value of fossil fuel companies. I present a conceptual trilemma model showing that fossil fuel companies’ existence is threatened by a carbon tax. To understand this paradox, I offer non-mutually exclusive reasons why fossil fuel companies might support carbon taxes. Oil and gas companies could use a carbon tax to get rid of the competition from coal, create a level playing field and remove regulatory uncertainty. Or they think that these taxes will not affect them because demand for oil and gas is inelastic or that international coordination will fail and lead to leakages. Finally, it could be that this is simply a communication exercise and that a carbon tax helps them shift the responsibility for climate change from fossil fuel companies to customers, voters and elected officials.
An Approach for Preliminary Landslide Scarp Assessment with Genetic Algorithm (GA)

For the investigation of landslide mass movement scenarios through numerical simulation, a well-defined released mass and a precise initial source area are required as prerequisites. In the present study, we present a genetic algorithm-based approach for preliminarily assessing the landslide scarp when the local field data are limited, using an ellipse-referenced idealized curved surface (ER-ICS)—a smooth surface constructed with respect to an ellipse. According to a specified depth at the center, there are two distinct curvatures along the major and minor axes, respectively. To search for the most appropriate ICS, the reference ellipse is translated, rotated, and/or side-tilted to achieve the optimal orientation for meeting the best fitness to the assigned condition (delineated area or failure depths). The GA approach may significantly enhance the efficiency, by reducing the number of candidate ICSs and notably relaxing the searching ranges. The proposed GA-ER-ICS method is examined and shown to be feasible, by mimicking the source area of a historical landslide event and through application to a landslide-prone site. In addition to evaluating the fitness of the ICS-covered area with respect to the source scarp, the impacts of various ICSs on the flow paths are investigated as well.
Intercomparison of Cloud Vertical Structures over Four Different Sites of the Eastern Slope of the Tibetan Plateau in Summer Using Ka-Band Millimeter-Wave Radar Measurements

The eastern slope of the Tibetan Plateau is a crucial corridor of water-vapor transport from the Tibetan Plateau to Eastern China. This is also a region with active cloud initiation, and the locally hatched cloud systems have a profound impact on the radiation budget and hydrological cycle over the downstream Sichuan Basin and the middle reach of the Yangtze River. It is noteworthy that there is a strong diversification in the characteristics and evolution of the ESTP cloud systems due to the complex terrain. Therefore, in this study, ground-based Ka-band millimeter-wave cloud radar measurements collected at the Ganzi (GZ), Litang (LT), Daocheng (DC), and Jiulong (JL) sites of the ESTP in 2019 were analyzed to compare the vertical structures of summer nonprecipitating clouds, including cloud occurrence frequency, radar reflectivity factor, cloud base height, cloud top height, and cloud thickness. The occurrence frequency exhibits two peaks on the ESTP with maximum values of ~20% (2–4 km) and 15% (7–9 km), respectively. The greatest (smallest) occurrence frequency occurs in the JL (GZ). The cloud occurrence frequency of all sites increases rapidly in the afternoon, and the occurrence frequency of the DC presents larger values at 2–4 km. In contrast, the occurrence frequency in the JL shows another increase from 2000 LT to midnight at 7–11 km. Stronger radar echoes occur most frequently in the LT at 5–7 km, and hydrometeor sizes and phase states vary dramatically in mixed-phase clouds. A small number of radar echoes occur at midnight in the JL. A characteristic bimodality of the cloud base height and top height for single-layer, double-layer, and triple-layer clouds was observed. Clouds show a higher base height in the GZ and higher top height in the JL. The ESTP is dominated by thin clouds with thicknesses of 200–400 m. The cloud base height, top height, and thickness exhibit an increase in the afternoon, and higher top height occurs more frequently from midnight to the next early morning in the JL because of its mountain-valley terrain.
Appropriate supplementation of testosterone alleviates post-stroke damage via decreasing inflammation and oxidative stress in aged male C57BL/6 mice

Stroke injury is closely related to testosterone levels. Testosterone supplementation in elderly men is seen to protect the cardiovascular system and reduce the risk of stroke. But this medication method is controversial. This study aims to investigate the effect of long-term testosterone supplementation on brain injury after stroke in aged mice. 60 male C57BL/6 mice,12-months of age were divided into 3 groups: low-dose group, high-dose group, and control group, each group was injected subcutaneously with 100 μL of sesame oil or 5 mg/kg or 50 mg/kg of testosterone (in 100 μL of sesame oil) twice per week, respectively. One week after the injection, stroke was induced by light. After the stroke, the injection continued for 6 weeks. The motion ability was measured by rotating rod and tail suspension. The brain injury was observed by naked eyes and TTC staining. In addition, we measured the inflammation (Tnf-α, Il-6, and Mcp-1) and oxidative stress (Malondialdehyde (MDA) and T-AOC) in the injured tissue 72 h post-stroke. Low-dose testosterone supplementation improved the motion ability and decreased brain injury. It also decreased the inflammatory factors (Tnf-α, Il-6, and Mcp-1), decreased MDA product, and increased T-AOC. High-dose testosterone supplementation not only reduced the motion ability and aggravated stroke injury, but also increased the inflammation, MDA level and decreased T-AOC level. In summary, supplementation of testosterone at normal levels in elderly mice can alleviate post-stroke injury by reducing inflammation and oxidative stress; however, excessive supplementation may cause unexpected injuries. This study has important implications for the application of testosterone replacement therapy.
Periacetabular Tumour Resection under Anterosuperior Iliac Spine Allows Better Alloprosthetic Reconstruction than Above: Bone Contact Matters

Background: Periacetabular resections are more affected by late complications than other pelvic resections. Reconstruction using bone allograft is considered a suitable solution. However, it is still not clear how the bone-allograft contact surface impacts on mechanical and functional outcome. Materials and methods: This paper presents the results of a retrospective analysis of 33 patients with resection of the entire acetabulum and reconstruction with an allograft-prosthetic composite for the period 1999 to 2010. Patients were divided in two groups, based on type of resection. In Group 1. patients had resections under anterosuperior iliac spine allowing the highest bone-allograft surface contact in reconstruction, while in Group 2 patients had resections over it. Results: Mechanical survival of the implant and Musculoskeletal Tumor Society functional score were calculated. Impact of age and artificial ligament were investigated as well. Patients in Group 1 had 38% mechanical failure rate of the implant while patients in Group 2 had 88%. Average functional score was higher in Group 1 compared with patients in Group 2. An artificial ligament was shown to have non-significant impact on survival of the reconstruction in Group 1, while significantly improving survival of reconstruction in Group 2. Conclusion: Bone-allograft contact matters: resection under anterosuperior iliac spine allows better mechanical survival and offers better reconstruction functional scores.
ZnSO4 spraying affects the growth and phytochemicals of Chinese kale microgreens

Abstract Chinese kale microgreens are gaining interest for its phytochemical compounds and anti-cancer properties mainly from glucosinolates. Zinc is an essential for plant growth and is involved with phytochemicals accumulation. This study investigated the different concentration of ZnSO4 on the enhancement of the phytochemicals and quality of Chinese kale microgreens. Three-day-old seedlings were sprayed with 2 and 4 mM of ZnSO4 until harvesting on days 4, 5, 6 and 7. ZnSO4 significantly decreased the fresh weight of 6 and 7-day-old microgreens and dry weight on the 7th day. The total glucosinolates, total phenolic compounds and total ascorbic acid, gradually rose as the age of microgreens increased. When the 3-day-old microgreens were sprayed at 6, 12 and 18 mM, the fresh and dry weight and hypocotyl length of 7-day-old microgreens significantly decreased as the concentration increases. ZnSO4 at 18 mM was the most effective in enhancing phytochemicals, resulting in increased DPPH radical scavenging activity and ferric reducing antioxidant power. This concentration also induced phenylalanine ammonia lyase activity resulting to an increase in total phenolic compounds. Moreover, ZnSO4 at 18 mM induced H2O2 content but are sufficiently countered with the increase in antioxidant enzymes namely superoxide dismutase, catalase, and ascorbate peroxidase. In conclusion, the 3-day-old microgreen was the most effective age for the start of the daily spraying of ZnSO4 before harvesting at 7-day-old. Higher concentrations of ZnSO4 (6-18 mM) enhanced the phytochemical compounds and enzymatic antioxidant activities but reduced growth. In contrast, lower concentration (< 4 mM) only improved microgreens growth.
Evaluation of High Doses of Phytase in a Low-Phosphorus Diet in Comparison to a Phytate-Free Diet on Performance, Apparent Ileal Digestibility of Nutrients, Bone Mineralization, Intestinal Morphology, and Immune Traits in 21-Day-Old Broiler Chickens

Simple Summary Phytic acid is the main storage form for phosphorus in plants. Although it is the main source of organic phosphorus in broiler diets, its utilization by monogastric animals is limited. In addition, phytic acid displays antinutritional effects, impacting optimal nutrient and energy digestibility. The supplementation of feed with phytases enables broilers to use phytate phosphorus more efficiently. Superdosing of phytase has been reported to have additional beneficial effects on the animal beyond the ones derived from the improved phosphorus utilization. This study tried to elucidate the mechanisms related to the immune response and mucosal morphology contributing to those overall beneficial effects. Although addressing performance was not the primary target of the study, performance improved linearly with increasing levels of phytase. The use of increasing doses of phytase showed linear increases in apparent ileal digestibility of crude protein, crude ash, and phosphorus. Jejunal crypt depth decreased with the addition of phytase to a low-protein diet, as well as the content of CD3-positive intraepithelial lymphocytes, but the results could not demonstrate clear differences between phytase doses in these specific parameters. Abstract The supplementation of feed with phytases enables broilers to utilize more efficiently phosphorus (P) from phytic acid (IP6), the main storage form of P in plants. The current study evaluated the addition of 500, 1000, and 3000 FTU of phytase per kg to a phytate-containing diet with low P level (LP) fed to broilers from 1 to 21 days of age and compared it to a hypoallergenic phytate-free diet (HPF). There was a linear improvement in performance parameters with increasing levels of phytase in the LP diet (p < 0.001). Apparent ileal digestibility of crude protein, P, and some amino acids, increased with phytase. Crude ash, P, and the calcium content of tibia bones linearly increased with increasing levels of phytase (p < 0.001). Crypt depth (related to body weight) in the jejunum epithelium linearly decreased with phytase addition (p < 0.001). Cecal crypt depth decreased with phytase supplementation (p = 0.002). Cecum tissue showed lower counts of CD3-positive intraepithelial lymphocytes in broilers receiving the phytase in comparison to LP (p < 0.001), achieving similar counts to HPF-fed broilers. Although results from the current study seem to point out some mechanisms related to the immune response and mucosal morphology contributing to those overall beneficial effects, no clear differences between different phytase doses could be demonstrated in these specific parameters.
Reassessing the "Proofreading Trap": ESL Tutoring and Writing Instruction

The Writing Center Journal Volume 24, No.1 Fall/Winter 2003 by Sharon A. Myers ESL writers present a common dilemma to writing centers—the desire for sentencelevel interventions from their tutors. Our staff often experience such interventions as contradicting the aim of writing centers, formulated by Stephen North as making "sure that writers, and not necessarily their texts, are what get changed by instruction" (438). The job of writing center tutors, North stated, "is to produce better writers, not better writing" (438). The sentence-level demands of ESL students, however, are seen as "editing. " Eric Hobson expresses this attitude in an article about writing center pedagogy in which he complains that during the period between the late 70s and early 80s, writing courses dealt with writing (e.g., invention, drafting, revision, development of authors’ voices, etc.) while writing center staff were allocated the demanding and ethically questionable task of "cleaning up" writers’ editing skills, of eradicating minority dialects . and of "dealing with" non-native writers. (155-166) It is easy to understand why, faced with cutting through the confused syntactic and lexical tangles entwined in the sentences of second-language texts, writing specialists might much prefer to discuss issues of content and organization. Giving students correct grammar or more appropriate vocabulary is perceived as "fixing" the paper, something understood to violate the autonomy of the writer and the integrity of the work’s authorship. Reassessing the “Proofreading Trap”: ESL Tutoring and Writing Instruction
Asian soybean rust management based on leaf area index and multisite fungicide

ABSTRACT Soybean foliar diseases negatively affect leaf area index (LAI) and compromise the main structure for photosynthesis and grain yield. The objective of this study was to propose a new methodology to determine the commencement of fungicide application based on the soybean LAI, spray volumes, and the inclusion of a multisite fungicide to control Asian soybean rust (ASR). The study was implemented in a randomized block design at two locations, with four replicates in a factorial scheme plus one additional treatment (4 × 2 × 2 + 1) - four soybean LAI (0.9, 1.8, 3.6, and 6.1) indicating the initiation stages of fungicide applications, two spray volumes (70 and 120 L ha-1), with or without multisite fungicide (mancozeb), and a control treatment without fungicide. The spray deposition on plants did not differ between the treatments for 1.8 and 3.6 LAI. Treatments including the multisite fungicide for LAI between 3.6 and 6.1 for both spray volumes presented superior ASR control results. The highest soybean yields were observed when fungicide application started at 3.6 LAI for both spray volumes. The best correlation between disease control and grain yield occurred when the applications started at 3.6 LAI with 70 L ha-1 spray volume and the multisite fungicide.
Characterizing Approximate Adders and Multipliers for Mitigating Aging and Temperature Degradations

The performance of nanoscale semiconductor technologies has become susceptible to high temperatures and aging phenomena. While guard-bands have conventionally been used to combat degradation-induced timing violations, approximations have recently been leveraged to compensate for degradations in lieu of adding timing guard-bands, without a loss in performance. However, only simple approximation techniques such as truncation have been considered in prior work. In this paper, a wide range of approximate arithmetic circuits including adders and multipliers using various sophisticated approximation techniques are investigated to cope with aging- and temperature-induced degradations. To this end, approximate circuits are first characterized for their delay increase under degradations. With this, we then determine the approximation level required to compensate for guard-bands under different degradations. Degradation-aware logic synthesis results show that the simple use of truncated arithmetic circuits leads to a higher quality loss compared to using other approximate circuits. However, a truncated multiplier has the lowest error distance towards a reliable operation in 10 years. The approximate multipliers with configurable error recovery are most suitable when the level of degradation is higher, e.g., at a temperature of 70 °C. The characterization of degradation at the circuit level is then used for design exploration at the architecture level without the need for further gate-level simulations. For three different image processing applications, experimental results show that guard-bands can be mitigated while maintaining an output result with a high visual quality.