Miracle-dz/UniFAR-FTUs huggingface dataset:
Analisis Sistem Pengendalian Intern Penerimaan Pajak Bumi dan Bangunan Perdesaan dan Perkotaan (PBB-P2) pada Badan Pendapatan Daerah Kabupaten Langkat

Penelitian ini bertujuan untuk mengungkap dan menganalisis Sistem Pengendalian Intern Pajak Bumi dan Bangunan Daerah Perdesaan dan Perkotaan pada Badan Pendapatan Daerah Langkat. Pendekatan penelitian ini adalah deskriptif kualitatif. Hasil penelitian ini menunjukkan bahwa sistem pengendalian intern Badan Pendapatan Daerah Langkat sudah efektif dan telah mengacu pada unsur-unsur Sistem Pengendalian Intern Pemerintah dan sudah sesuai dengan Peraturan Pemerintah Nomor 60 Tahun 2008 tentang Pengendalian Intern Pemerintah. sistem. Namun, terkadang masih ada masalah jaringan yang dapat menghambat operasional kantor.
Designing wearable sensors for Preventative Health: An exploration of material, form and function

The financial burden on global healthcare systems has reached unprecedented levels and as a result, attention has been shifting from the traditional approach of disease management and treatment towards prevention (Swan, 2012). Wearable devices for Preventative Health have become a focus for innovation across academia and industry, thus this thesis explores the design of wearable biochemical and environmental sensors, which can provide users with an early warning, detection and monitoring system that could integrate easily into their existing lives. The research aims to generate new practical knowledge for the design and development of wearable sensors and, motivated by the identification of compelling design opportunities, merges three strands of enquiry. The research methodology supports this investigation into material, form and function through the use of key practice-based methods, which include Participatory Action Research (active immersion and participation in a particular community and user workshops) and the generation and evaluation of a diverse range of artefacts. Based on the user-centred investigation of the use case for biochemical and environmental sensing, the final collection of artefacts demonstrates a diverse range of concepts, which present biodegradable and recyclable nonwoven material substrates for the use in non-integrated sensors. These sensors can be skin-worn, body-worn or clothing-attached for in-situ detection and monitoring of both internal (from the wearer) and external (from the environment) stimuli. The research proposes that in order to engage a broad section of the population in a preventative lifestyle to significantly reduce the pressure on global healthcare systems, wearable sensors need to be designed so they can appeal to as many users as possible and integrate easily into their existing lifestyles, routines and outfits. The thesis argues that this objective could be achieved through the design and development of end-of-life considered and cost-effective substrate materials, non-integrated wearable form factors and meticulous consideration of a divergent range of user needs and preferences, during the early stages of design practice.
Association Between Quality of Nursing Care in the ICU and Severity of Illness

Background: The quality of nursing care can be affected by a variety of factors. This study aims to determine the correlation between quality of nursing care and severity of illness (SOI) in patients admitted to intensive care unit (ICU). Methods: This descriptive-correlational study was performed during November 2018 to January 2019 in Ayatollah Mousavi Hospital, Zanjan, Iran. The sample included 50 ICU patients who were recruited by convenience sampling. The data were collected using ICU quality of nursing care scale and the Sequential Organ Failure Assessment (SOFA) score within the first seven days of hospitalization and were analyzed by descriptive and non-parametric statistical tests (Friedman, Wilcoxon signed-rank, and Spearman’s rho) using SPSS software version 22. The significance level was set as 0.05. Results: The mean score of quality of nursing care was 86.62(2.19) and there was a significant difference among the seven days (p<0.001). Also, the mean score of SOI was 6.4(2.31) and it was constant in the first to third days of hospitalization and decreased by the fourth day of admission. There was a significant indirect correlation between the quality of nursing care and SOI from the fourth day onwards (p<0.05). Conclusion: There was a significant inverse relationship between quality of nursing care and SOI from the fourth to the seventh day of hospitalization. It seems that nursing care delivery in the ICU is mainly routine and does not follow the holistic model of care. Therefore, the severity of the illness and the changing needs of patients admitted to the ICU require that care models be tailored to these changes.
The number of circulating CD34-positive cells is an independent predictor of coronary artery calcification progression: Sub-analysis of a prospective multicenter study

Background Decreases in circulating CD34-positive cells are associated with increases in cardiovascular events. We investigated the association between the number of CD34-positive cells and the progression of coronary artery calcification (CAC), a marker of atherosclerosis, in patients with hypercholesteremia under statin therapy in a sub-analysis of a multicenter study. Methods In the principal study, patients with CAC scores of 1–999 were treated with pitavastatin. Measurement of CAC by non-enhanced computed tomography and a blood test were performed at baseline and at 1-year follow-up. Patients were divided into two groups: CAC progression (change in CAC score > 0) and non-progression. The number of circulating CD34-positive cells was counted using flow cytometry. Results A total of 156 patients (mean age 67 years, 55% men) were included in this sub-analysis. CD34 positive cell numbers at baseline as a continuous variable was inversely correlated with annual change in the log-transformed CAC score (r = –0.19, p = 0.02). When patients were divided into high and low CD34 groups based on the median value of 0.8 cells/μL, the adjusted change in CAC score in the low-CD34 group was significantly greater than that in the high-CD34 group (54.2% vs. 20.8%, respectively, p = 0.04). In multiple logistic analysis, a low CD34-positive cell number was an independent predictor of CAC progression, with an odds ratio of 2.88 (95% confidence interval 1.28–6.49, p = 0.01). Conclusions Low numbers of CD34-positive cells are associated with CAC progression in patients with hypercholesterolemia under statin therapy. The number of CD34-positive cells may help to identify patients at increased cardiovascular risk.
Experimental Studies of Transonic Flow Field Near a Longitudinally Slotted Wind Tunnel Wall

The results of detailed, parametric experiments are presented for the near-wall flow field of a longitudinally slotted transonic wind tunnel. Existing data are reevaluated and new data obtained in the Langley 6- by 19-Inch Transonic Wind Tunnel are presented and analyzed. In the experiments, researchers systematically investigate many pertinent wall-geometry variables such as the wall openness and the number of slots along with the free-stream Mach number and model angle of attack. Flow-field surveys on the plane passing through the centerline of the slot were conducted and are presented. The effects of viscosity on the slot flow are considered in the analysis. The present experiments combined with those of previous investigations, give a more complete physical characterization of the flow near and through the slotted wall of a transonic wind tunnel.
Recent advances in the development of allosteric protein tyrosine phosphatase inhibitors for drug discovery

Protein tyrosine phosphatases (PTPs) superfamily catalyzes tyrosine de‐phosphorylation which affects a myriad of cellular processes. Imbalance in signal pathways mediated by PTPs has been associated with development of many human diseases including cancer, metabolic, and immunological diseases. Several compelling evidence suggest that many members of PTP family are novel therapeutic targets. However, the clinical development of conventional PTP‐based active‐site inhibitors originally was hampered by the poor selectivity and pharmacokinetic properties. In this regard, PTPs has been widely dismissed as “undruggable. ” Nonetheless, allosteric modulation has become increasingly an influential and alternative approach that can be exploited for drug development against PTPs. Unlike active‐site inhibitors, allosteric inhibitors exhibit a remarkable target‐selectivity, drug‐likeness, potency, and in vivo activity. Intriguingly, there has been a high interest in novel allosteric PTPs inhibitors within the last years. In this review, we focus on the recent advances of allosteric inhibitors that have been explored in drug discovery and have shown an excellent result in the development of PTPs‐based therapeutics. A special emphasis is placed on the structure–activity relationship and molecular mechanistic studies illustrating applications in chemical biology and medicinal chemistry.
Building A Foundation for Tax Compliance in The Time of The COVID-19 Pandemic

The COVID-19 pandemic has had a significant impact on the economy, including the taxation sector. This tumultuous period for taxpayers and the Government can be a golden opportunity to transform the system and institutional governance to create a firm foundation for increasing tax compliance and by extension, tax revenue. This paper examines strategies that are necessary to face spate of changes and uncertainty caused by the COVID-19 pandemic as well as laying the framework for post COVID-19 reality that is characterized by sustainable tax compliance. The results of this study reached the conclusion that the basic concept of the relationship between the Government and taxpayers as a social contract or fiscal contract should underpin the three phases of the formulation of changes in tax policy. For changes to have long-term and sustainable impact, there is need to strike a balance between the three pillars in tax administration, namely, enforcement, facilitation, and trust.
Effect of the Axial Spacing between Vanes and Blades on a Transonic Gas Turbine Performance and Blade Loading

Abstract Unsteady numerical simulations have been conducted to investigate the effect of axial spacing between the stator vanes and the rotor blades on the performance of a transonic, single-stage, high-pressure, axial turbine. Three cases were considered, the normal case, which is based on the geometry of a commercial jet engine and has an axial spacing at 50% blade span equal to 42% of the vane axial chord, as well as two other cases with axial spacings equal to 31 and 52% vane axial chords, respectively. Present interest has focused on the effect of axial gap size on the instantaneous and time-averaged flows as well as on the blade loading and the turbine performance. Decreasing the gap size reduced the pressure and increased the Mach number in the core flows in the gap region. However, the flows near the two endwalls did not follow monotonic trends with the gap size change; instead, the Mach numbers for both the small gap and the large gap cases were lower than that for the normal case. This Mach number decrease was attributed to increased turbulence due to the increased wake strength for the small gap case and an increased wake width for the large gap case. In all considered cases, large pressure fluctuations were observed in the front region of the blade suction side. These pressure fluctuations were strongest for the smaller spacing. The turbine efficiencies of the cases with the larger and smaller spacings were essentially the same, but both were lower than that of the normal case. The stator loss for the smaller spacing case was lower than the one for the larger spacing case, whereas the opposite was true for the rotor loss.
Novel approaches for the characterisation of Plasmodium variant surface antigens

The aim of this research was to identify the erythrocyte surface antigens of P. falciparum-irffected erythrocytes (lEs) that are expressed following selection of the parasite for adhesion to the placental receptor chondroitin sulphate A (CSA). These surface antigens are considered potential vaccine targets against pregnancyassociated malaria (PAM). Typically P. falciparum surface antigens are highly sensitive to treatment of the IE with the protease trypsin; however, variant surface antigen (VSA) mediated adhesion to CSA has often been found to be relatively trypsin-resistant. In this study the protease sensitivity of the VSA of CSA binding lEs was determined with regard to serum IgG recognition and placental receptor binding. Discordance between the protease sensitivity for these phenomena was identified; this may have implications for PAM vaccine design. The completion of several Plasmodium genome sequences and advances in mass spectrometry have opened up the field of proteomics to the study of the malaria parasite. Proteomic methods have been applied to the study of Plasmodium VSA. However, the initial step of these methods, surface antigen labelling, proved problematic. Therefore, this thesis concentrates on the optimisation of these techniques. An antibody to the Plasmodium falciparum erythrocyte protein-i (PfEMP1) family was raised and characterised. This reagent in combination with the advances made for IE surface labelling will be a valuable tool for future studies of VSA expression. Western blotting was also applied to investigate the developmental regulation, post-translational processing and surface trypsinisation sensitivity of two candidate IE surface antigens, Plasmodium falciparum Cysteine Repeat Modular proteins 1 and 2. During the optimisation of biochemical techniques, a study to investigate the effect of mosquito passage on Plasmodium chabaudi variant surface antigen expression was initiated. Potential surface antigens whose expression associates with mosquito transmission were identified.
Optimisation Of Stilling Basin Chute Blocks Using a Calibrated Multiphase RANS Model

Interaction between chute blocks and highly aerated flows has been studied in this paper. For this purpose, a RANS model coupled with a calibrated turbulent air entrainment model, VOF method and RNG k − e turbulence model have been employed. This has allowed analysing the complex multiphase flows behaviour in an USBR type II stilling basin with variable chute block height. Furthermore, conducted simulations exhibit some similarities with flow patterns detected in previous Bjump, hydraulic jump and highly aerated flows experimental studies. Finally, it has been also possible to identify two different mechanisms involving the chute blocks effect upon the flow: turbulent rough wall jet and flow deflector. Turbulent wall jet mechanism takes place for lower values of the chute block height and helps to stabilise hydraulic jump for deficient tail water conditions while flow deflector has not shown to be a desirable mechanism in a stilling basin.
Effectiveness of Work-Integrated Learning Partnerships: Case Study of Cooperative Education in Agricultural Tertiary Education

The growing demand for promoting the role of higher education institutions in sustainability has contributed to creating new partnerships with other actors. In the field of education, the formation of cooperative education (co-op) partnerships was adopted as a strategy for work-integrated learning in cooperation with industry. This study investigated the effectiveness of co-op partnerships and the factors that influence them in the context of tertiary agriculture education in Saudi Arabia. A random sample of 130 co-op students was selected within the Bachelor of Agricultural Sciences delivered by the College of Food and Agriculture Sciences at King Saud University. The satisfaction level of students was explored in terms of four main areas, namely, the quality of the program design, organizational climate, personal and professional qualities, and program learning outcomes. The majority of students (70%) were highly satisfied with the quality of the program design, while they had a moderate level of satisfaction regarding the organizational climate of the co-op program (74.6%). Furthermore, 85.4% of students were highly satisfied regarding the learning outcomes they gained. The results also revealed that there were significant positive relationships between the level of satisfaction of students regarding program learning outcomes and their quality assessments of the program design, personal and professional qualities, and organizational climate. The measurement scale used in this study may assist in assessing the sustainability of co-op partnerships. Moreover, understanding the satisfaction level of students can help to identify areas that should be improved and, in turn, contribute to improving the governance and sustainability of co-op partnerships for all stakeholders.
Development of Poplar Based Agroforestry System

Uttar Pradesh Forest Department started research work on poplars in 1950, by importing fast growing clones from Europe and China. As clones imported were from higher latitude, they did not perform well in foot hills and tarai, where, deep, fertile and irrigated sites were available for its cultivation. Success in agroforestry was achieved by introducing Australian clones of American origin. Farmers adopted it as commercial crop due to its fast growth, deciduous nature, clean and straight bole, etc. Removal of restriction on felling and transport by State Governments encouraged farmers to adopt poplar on large scale. Development of local markets and higher demand by industries, helped poplar cultivation in yielding much higher return than field crop. Poplar cultivation activity has generated huge employment in rural sector and has over all improved rural economy. As such, it is going to stay and expand. To maintain better and higher production of poplar wood, selection of new clones is necessary. Key of success of agroforestry programme is source identified planting material at proper time of proper site.
Analysis of control interactions in multi-infeed VSC HVDC connections

The number of voltage-source converters connected to the power system is increasing. This has led to concerns about the impact of control interactions between converters and their influence on the system stability. Recent grid codes consider such interactions as low-frequency disturbances between the converters and neglect network dynamics. This paper studies the control interactions and interferences in a multi-infeed power system with two converters. The phenomenon is studied in the frequency domain by using the admittance-based stability assessment. Harmonic stability under different network characteristics is addressed. The analysis shows that resonances in the system can lead to instabilities when appearing within the control bandwidth, thereby implying the necessity to also consider higher-frequency dynamics.
Life cycle assessment of soybeans production and processing system into soy oil using solvent extraction process

Agricultural operations have been indicated to be some of the major emitters of greenhouse gases (GHG), particularly methane (CH4) and nitrous oxide (N2O) around the globe, and it is important to determine the quantity emitted and how they can be reduced. The environmental impacts associated with field production and industrial processing of soybean into crude vegetable oil in Nigeria was therefore studied using the life cycle impacts assessment tool. The emission from the various inputs into the system was aggregated into a large inventory table. The functional unit was defined as one kilogram of soybean. The environmental impact categories used in this study are global warming, acidification, eutrophication and ozone layer depletion. Of these four environmental impacts, global warming has the highest impact score of 4.7516E-01 kg CO2 equivalent, followed by eutrophication (1.6414E-04 kg NO3 equivalent). Ozone layer depletion has the lowest environmental impact score of –2.8207E-07 kg R11 equivalent. The high impact score of global warming is due to the high emission of CO2 gas from fossil fuel and biomass combustion during field operations and processing of soybeans.
Neuroimaging Features and Associated Factors in Multiple Sclerosis Patients: A Perspective from a Private Care Center in Addis Ababa, Ethiopia

Background Brain and spine magnetic resonance image (MRI) have an invaluable importance in diagnosing multiple sclerosis (MS) in low prevalence countries such as Ethiopia. The objective of our study was to characterize the neuroimaging features and associated factors in Multiple sclerosis patients in Addis Ababa, Ethiopia. Method A cross-sectional observational study was conducted in 30 multiple sclerosis patients at Yehuleshet Specialty Clinic, Addis Ababa, Ethiopia. Both descriptive and analytical statistics were used to analyze the data. Results We have enrolled 30 patients with confirmed multiple sclerosis and clinically isolate syndrome. The mean age was 34.7 years (1SD=8.9). Female accounted 86.7%. The mean duration of illness was 3.4 years (1SD=3.1) (range: 1 – 11 years). Relapsing and remitting variant was the commonest sub type (66.7%). Alcohol use and head injury were the commonest identified risk factors reported by the patients. Classical radiological features of MS such as white matter lesions involving juxtacortical, U-fiber, corpus callosum (CC), and Dawson's finger projections pattern were observed in 46.7%, 23.3%, 70%, and 40% respectively. Cervical and thoracic cords were affected in 40% and 6.7% respectively. Global cortical and CC atrophy was observed in 16.7% and 6.7% respectively. Advanced age was associated with lesions of corpus callosum when adjusted for duration of illness and history of head injury (AOR 1.13, 95% CI 1.01–1.28, p=0.04). Conclusion Typical neuroimaging features of MS were prevalent among Ethiopian MS patients. Age was an independent predictor of lesions involving corpus callosum. Global cortical atrophy was common among Ethiopian MS patients.
Emerging off‐label esthetic uses of botulinum toxin in dermatology

Botulinum toxin is a neurotoxic protein produced by Clostridium botulinum, the bacterium responsible for botulism. Botulinum toxin was first used for therapeutic indications in the 1970s for the treatment of strabismus. With greater understanding of its underlying physiology and safety profile, the use of botulinum toxin has now expanded to a range of cosmetic and medical indications. We performed a systematic review of current literature on the applications of botulinum toxin on off‐label esthetic uses. Electronic databases were searched for original published studies including randomized trials, observational or cohort studies, as well as relevant case reports. To add to the body of evidence, our review summarizes and synthesizes key study characteristics, results, and level of evidence for each use case. Although the body of evidence remains weak, there is increasing support for the use of botulinum toxin in emerging off‐label esthetic uses of botulinum toxin in dermatology.
The Influence of Financial Literacy on Investment Decisions During the Pandemic

This study aims to determine the effect of financial literacy on investment decisions during the pandemic. The object of this research is the students of the Faculty of Economics and Business, Universitas Muhammadiyah Sumatera Utara by using the Slovin formula in taking the sample. The test is carried out by simple linear regression where the classical assumptions have been tested previously. The results showed that there was a significant influence of financial literacy on investment decisions. The pandemic has made everyone, including students, start investing for future needs. Students are advised to continue to improve their financial literacy for the better. With increasing financial literacy, financial management will also be better and lead to investment.