Miracle-dz/UniFAR-FTUs huggingface dataset:
Evaluation of interaction effect of drought stress with ascorbate and salicylic acid on some of physiological and biochemical parameters in okra (Hibiscus esculentus L.).

Drought stress causes oxidative damages in plant cells. Two of compounds which have antioxidative characteristic are Salicylic Acid (SA) and Ascorbic acid (As). These compounds can decrease drought effects in plants under stress. In this research, the drought stress was treated in 3 levels of drain (Control, 1/3 Field Capacity, 2/3 Field Capacity). Then, interaction effects of drought stress with SA and As on some of physiological and biochemical parameters of hibiscus esculents L plants were investigated. In recent research, we evaluated parameters such as; leaf area, Dry and Fresh Weight of leaf (DW and FW), lipid per oxidation amount, proline content, sugar content, ion leakage, protein content and photosynthetic pigments content. The results shown that leaf area, FW and DW parameters decreased compared to check under stress significantly. Lipid per oxidation, sugar and proline content and ion leakage increased in plants were under with drought stress. Reduction of protein content in this condition showed that drought stress effected protein biosynthesis and degradation. Moreover, significantly reduction of photosynthetic pigments content showed that stress effected photosynthetic process. Based on our results it seems that salicylic and ascorbic acid can considerably alleviated oxidative damage that occurred under drought stress condition. Therefore, we concluded that salicylic acid and ascorbic acid in the concentration 1 mM have in mitigation of stress caused by drought stress.
Functional and Structural Characterization of a Human H4 Histone Gene Promoter: a Thesis

FUNCTIONAL AND STRUCTU CHACTERIZATION OF A HU H4 HISTONE GENE PROMOTER Kenneth Lynn wright November 1990 Thesis Advisor: Janet L. Stein Department: Cell Biology Expression of the cell cycle dependent FOI08 human H4 histone gene is regulated at both the transcriptional and post-transcriptional levels. We have investigated the promoter elements mediating the transcriptional aspects of its regulation. A detailed in vivo and in vitro transcriptional analysis of promoter deletion mutants from this gene has identified three positive regulatory elements and two potentially negative regulatory elements within the first 1000 base pairs upstream of the transcription initiation site. In addition, the minimal promoter located within the first 70 base pairs is required for accurate transcription initiation and contains one of two in vivo identified protein-DNA interactions , site II. Binding of the nuclear factor HiNF-D to this region was correlated with the turn-on of histone gene transcription following stimulation of quiescent normal diploid fibroblasts to re-enter the proliferati phase. The most proximal positive regulatory element contains the other in vivo identified protein-DNA interaction, site I. Results from a series of in vitro protein-DNA interaction studies revealed the binding of two nuclear factors to this element. One protein, HiNF-C , is indistinguishable from the transcription factor Sp1 while the other , HiNF-E, is a novel, potentially histone-specific member of the ATF transcription factor family. Binding of HiNF-C was required to stabilize the interaction of HiNF-E and together this region stimulated transcription 5 fold. The near-distal transcription activator region lies between -418 and -213 base pairs and forms a single proteinDNA complex, H4UA-1. The interaction domain for H4UA-1 contains recognition sequences for both the thyroid hormone receptor and the nuclear factor CTF /NF-1. The far-distal activator region (-730 and -589 base pairs) was the strongest positive regulatory element identified in the H4 promoter. This region increased transcription 10 fold and contains three protein-DNA interactions. One of the factors H4UA-2, is an ATF transcription factor closely related to the HiNF-E interaction in the proximal positive element. These studies have defined the functional human H4 histone promoter to be a complex, modular structure extending at least 1000 base pairs. vii TABLE OF CONTENTS Page ACmOWLEDGEMENTS.
Availability of phosphorus from field bean [Vicia faba] and lupin [Lupinus albus] seeds to broiler chickens

Experiment was conducted on 64 broiler chickens from 0 to 18 days of age to evaluate phosphorus availability from lupin and field bean. As indicators, bone mineralization and breaking strength and the retention of P fractions were used. Body weight at 18 days of life was reduced (P < 0.01) when P deficient semi-synthetic diet without inorganic P (PO) was fed. Femur ash content and tibia breaking strength were lowest and similar in chickens fed P-deficient (PO) and field bean containing (BPO) diets. Their femur ash content and tibia breaking strength were lower by about 12% (P^0.05) and 45% (P<0.01) than of chickens fed a diet with 0.2% of inorganic P (P2) which showed the best bone mineralization. Phosphorus was more available from lupin than from field bean (judged from breaking strength measurements: respectively 53 and 0% compared with inorganic P considered as 100% available). The results are discussed with respect to validity of the assays used and anti-nutritive factors in field bean.
The Role of Service Quality, Employee Satisfaction and Loyalty on the Effective Human Resource Management in the Pharmacies in Thailand: Mediating Role of Customer Satisfaction

The primary aim of the study is to examine the role of service quality, employee satisfaction and loyalty on the effective human resource management (HRM) in the pharmacies in Thailand. The secondary aim of this article is to identify the mediating role of customer satisfaction on the link of the service quality, employee satisfaction and loyalty on the effective HRM in the pharmacies in Thailand. The data were gathered from the HR employees that are working for the implementation of HR policies in the organization. The findings exposed that positive and significant link among the service quality, employee satisfaction and loyalty on the effective HRM in the pharmacies in Thailand. The results also uncovered that the customer satisfaction mediates the relationship among the service quality, employee satisfaction and loyalty on the effective HRM in the pharmacies in Thailand positively. These findings give the guideline to the regulation making authorities that they should increase their focus on the employees satisfaction and loyalty that enhance the effectiveness of HRM and also enhance the companys performance.
Visible/solar-light driving photocatalytic activity of TiO2 nanotubes upon coating with phosphotungstate hybrid

ABSTRACT This study introduces coloured titanium dioxide nanotubes by phosphotungstate hybrid as an activated photocatalyst for the degradation of organic pollutants under visible and solar light irradiation. The prepared coloured TiO2 nanotubes are characterised by Fourier transform infrared spectroscopy, powder X-ray diffraction, diffuse reflectance spectrometry, scanning electron microscopy, energy-dispersive X-ray spectroscopy, transmission electron microscopy and N2 adsorption–desorption isotherms. Then, performance of this catalyst is evaluated using decolourisation of model dyes methylene blue (MB), methyl orange (MO) and mixtures of MB and MO solutions. It is confirmed that the presence of coloured hybrid in the context of white TiO2 enables photocatalytic activity in the visible and solar light. Also, its noticeable efficiency is verified in the photodegradation of organic dyes and its reusability without any significant loss of activity. Removal is via combination of adsorption and then photocatalytic degradation through oxidation by •OH radicals or reduction by reduced polyoxometalate. While the visible light is not able to degrade alone MO solution in the presence of composite, it degrades the MO mixed with MB solution.
Herbicide Efficacy for Production of Container Ornamentals

A study was conducted to evaluate efficacy of 17 PRE herbicides on seven weed species that are important competitors in container-grown ornamentals. Treatments included napropamide, metolachlor, acifluorfen, lactofen, oxyfluorfen, oryzalin, pendimethalin, prodiamine, trifluralin, isoxaben, oxadiazon, simazine and combination products. Control was evaluated by counting weed seedlings 42, 202, and 249 d after treatment. Some treatments provided nearly total control of less than 1.0 seedling per container at each rating over two years. Those treatments were: common groundsel—diphenyl ethers, isoxaben, oxadiazon, oxyfluorfen + oryzalin, and oxyfluorfen + pendimethalin; prostrate spurge—pendimethalin, prodiamine, prodiamine-ABD, trifluralin, oxadiazon, isoxaben + oryzalin, and methazole + prodiamine; common chickweed—isoxaben and isoxaben + oryzalin; hairy bittercress—oxyfluorfen, pendimethalin, prodiamine, prodiamine-ABE, oxadiazon, oxyfluorfen + oryzalin, oxyfluorfen + pendimethalin, and methazole + prodiamine; common ragweed—oxyfluorfen, prodiamine-ABD, methazole + prodiamine; Virginia pepperweed—lactofen, oxyfluorfen, oryzalin, pendimethalin, prodiamine, prodiamine-ABD, isoxaben, oxadiazon, oxyfluorfen + oryzalin, oryzalin + pendimethalin, isoxaben + oryzalin, and methazole + prodiamine; horseweed—oxyfluorfen, dinitroanilines, oxadiazon, oxyfluorfen + oryzalin, oxyfluorfen + pendimethalin, isoxaben + oryzalin, and methazole + prodiamine.
Life-history traits of the bivalve Spisula subtruncata (da Costa) in the Ligurian Sea (North-Western Mediterranean): The contribution of newly settled juveniles*

A population of Spisula subtruncata was studied in four different years (1983-1984; 1990-1993) on a shallow sandy bottom in the Ligurian Sea. Throughout the studied period, the S. subtruncata population was characterised by wide seasonal and interannual fluctuations both in abundance and biomass. Its life-cycle was normally annual, and there was an almost complete disappearance of the bivalve during winter months. The population of Spisula subtruncata was characterised by the dominance of juvenile forms and very few adults (maximum total length observed, 13 mm). Population size varied according to recruitment success. In the 1 mm samples, Spisula was particularly abundant within the community during the spring-summer period of 1991, with peaks of density and biomass of 1017 individuals m-2 (± 30.9 std) and 114.5 mg AFDW m-2 in May. From January 1991 to February 1993 the juvenile density of the bivalve was measured in meiofaunal samples. Juveniles were characterised by wide seasonal fluctuations, with density peaks in May (10,350 individuals m-2 ± 248 and 11,403 individuals m-2 ± 378, in 1991 and 1992, respectively). A mortality rate higher than 90% was estimated (measured as the difference between the density peak of juveniles and the density of the following peak of adults). Production was 0.58 (1983-84), 0.44 (1991-92) and 0.12 g m-2 yr-1 (1992-93). Considering also the contribution of temporary meiofauna, secondary production raised up to 0.52 in 1991-1992; and to 0.18 g m-2 yr-1 in 1992-93. The year 1990 was characterised by very low density so that no production value was estimated. A number of features are discussed: the variability observed in the demographic structure of the bivalve with the latitudinal gradient; the relation between population structure and production values; and the contribution of the smallest size classes to energy flow.
Bazedoxifene Plays a Protective Role against Inflammatory Injury of Endothelial Cells by Targeting CD40

The inflammatory response and oxidative stress play key roles in the formation and development of atherosclerosis. Bazedoxifene is a new IL6/GP130 inhibitor recommended by the FDA for clinical use as a selective estrogen receptor modulator. However, its role in cardiovascular diseases has been poorly studied. In our study, we explored the mechanism of bazedoxifene's protective effect against inflammatory injury of vascular endothelial cells (VECs) stimulated by TNF-α. Various methods were used to verify the effect of bazedoxifene on VECs, including a cell viability assay, a wound healing assay, immunofluorescence staining, and western blotting. Our results showed that TNF-α could induce inflammatory damage to VECs, which manifested as upregulated expression of CD40, increased production of ROS, enhanced adhesion of THP-1 cells to VECs, and impaired viability and migration of VECs, while bazedoxifene could significantly reduce the endothelial damage caused by TNF-α. In addition, we found that an siRNA targeting CD40 dramatically alleviated the VEC damage induced by TNF-α. Therefore, we explored the potential relationship between bazedoxifene and CD40. Our data suggest that bazedoxifene has a protective effect against VEC damage induced by TNF-α and that its underlying mechanism may be related to the regulation of CD40.
Acute and chronic exercise influence serum brain‐derived neurotrophic factor in multiple sclerosis

Exercise has been shown to increase neurotrophin production in the brain and spinal cord and may be an effective countermeasure to minimize deleterious changes associated with neurodegenerative diseases such as multiple sclerosis (MS). We studied the acute and chronic impact of 8 weeks of aerobic exercise on serum brain‐derived neurotrophic factor (BDNF) in MS and matched controls. Eleven MS subjects and eleven healthy controls matched for age, weight, height, percent body fat and VO2peak completed the study. Subjects performed 30 minutes of cycle ergometry at 60% of VO2peak, three times a week for 8 consecutive weeks. Resting serum BDNF was lower in MS compared to controls at week 0 (p=0.03) and only tended to be lower at week 8 (p=0.07). Resting BDNF concentration in controls remained unchanged throughout the training intervention. However, resting BDNF increased at week 4 in MS subjects (p=0.04). Both MS and controls showed decreases in BDNF during a 3‐hour recovery following a single bout of exercise (p<0.001) but these responses were different between groups (p=0.01). Our study provides new evidence that exercise training may modulate BDNF at rest in MS. A single bout of exercise may also stimulate clearance of circulating BDNF. Further investigation is warranted to clarify the significance of these changes on neuroprotection.
Exercise right heart catheterization before and after balloon pulmonary angioplasty in inoperable patients with chronic thromboembolic pulmonary hypertension

Background * These authors contributed equally as last authors. Balloon pulmonary angioplasty is an evolving, interventional treatment option for inoperable patients with chronic thromboembolic pulmonary hypertension (CTEPH). Pulmonary hypertension at rest as well as exercise capacity is considered to be relevant outcome parameters. The aim of the present study was to determine whether measurement of pulmonary hemodynamics during exercise before and six months after balloon pulmonary angioplasty have an added value. Methods From March 2014 to July 2018, 172 consecutive patients underwent balloon pulmonary angioplasty. Of these, 64 consecutive patients with inoperable CTEPH underwent a comprehensive diagnostic workup that included right heart catheterization at rest and during exercise before balloon pulmonary angioplasty treatments and six months after the last intervention. Results Improvements in pulmonary hemodynamics at rest and during exercise, in quality of life, and in exercise capacity were observed six months after balloon pulmonary angioplasty: WHO functional class improved in 78% of patients. The mean pulmonary arterial pressure (mPAP) at rest was reduced from 41 ± 9 to 31 ± 9 mmHg (p < 0.0001). The mPAP/cardiac output slope decreased after balloon pulmonary angioplasty (11.2 ± 25.6 WU to 7.7 ± 4.1 WU; p < 0.0001), and correlated with N-terminal fragment of pro-brain natriuretic peptide (p = 0.035) and 6-minute walking distance (p = 0.01). Conclusions Exercise right heart catheterization provides valuable information on the changes of pulmonary hemodynamics after balloon pulmonary angioplasty in inoperable CTEPH patients that are not obtainable by measuring resting hemodynamics.
Transcriptome Analysis of ‘Haegeum’ Gold Kiwifruit Following Ethylene Treatment to Improve Postharvest Ripening Quality

Fruit ripening involves changes in physical, physiological and metabolic activities through the actions of enzymes and regulatory genes. This study was initiated to identify the genes related to the ripening of kiwifruit. Gold ‘Haegeum’ kiwifruit is a yellow-fleshed kiwifruit cultivar usually used for fresh marketing. The fruit is harvested at a physiologically mature but unripe stage for proper storage, marketing distribution and longer shelf life. To identify the differentially expressed genes (DEGs) during ripening, fruit treated with ethylene were compared with control fruit that ripened naturally without ethylene treatment. Firmness, respiration rate, ethylene production rate, total soluble solids (TSS), titratable acidity (TA), brix acid ratio (BAR) and overall acceptability were taken during the study as fruit ripening indicators. Total mRNAs were sequenced by Illumina high-throughput sequencing platform and the transcriptome gene set was constructed by de novo assembly. We identified 99,601 unigenes with an average length of 511.77 bp in transcriptome contigs. A total of 28,582 differentially expressed unigenes were identified in the ethylene treatment vs. control. Of these 28,582 unigenes, 13,361 and 15,221 genes were up- and downregulated, respectively, in the treated fruit. The results also showed that 1682 and 855 genes were up- and downregulated, respectively, more than 2-fold at p < 0.05 in fruit treated with ethylene as compared with the control fruit. Moreover, we identified 75 genes showing significantly different expression; 42 were upregulated, and 33 were downregulated. A possible category of the identified ripening-related genes was also made. The findings of this study will add to the available information on the effect of ethylene treatment on ripening and the related changes of kiwifruit at the genomic level, and it could assist the further study of genes related to ripening for kiwifruit breeding and improvement.
Microbial Consortium Promotes Growth of Zinnia and Balsam Seedlings Raised in pro trays

Zinnia and Balsam are flowering plants with high economic importance in floriculture. Inoculation of the planting medium with a beneficial microbial consortium is an innovative approach to produce quality and healthy seedlings in floriculture. In the present study the influence of a microbial consortium of the arbuscular mycorrhizal fungus (AMF) Funneliformis mosseae and a plant growth promoting rhizobacterium (PGPR) Bacillus sonorensis on flowering plants Zinnia and Balsam in pro-trays under poly house conditions was investigated. Estimation of various plant growth parameters such as plant height, stem diameter, bio-volume index, vigour index, plant strength, fresh weight, dry weight and nutrient uptake was carried out to analyse the ability of the consortium to improve seedling growth. Microbial parameters such as mycorrhizal root colonization and spore count, and population of PGPR in substrate was also studied. The results suggested that inoculating the substrate in pro trays before sowing the seeds with the consortium increased plant growth significantly compared to the uninoculated plants.
Antimicrobial Activities and GC-MS Analysis of Endophytic Fungi Isolated from Pluchea dioscoridis and Withania somnifera Medicinal Plants

Twenty three genera (46 species and 2 species variety) of endophytic fungi were isolated and identified from the leaves of Pluchea dioscoridis and Withania somnifera on GPY agar medium at 28°C. Alternaria, Aspergillus, Cladosporium and Setosphaeria were the most common genera isolated from P. dioscoridis and W. somnifera. The extracts of isolated endophytic fungi were tested for antimicrobial activities against nine strains of pathogenic bacteria and seven isolates of phytopathogenic fungi by disc diffusion method. Extracts of endophytic fungal showed antibacterial activity by different degrees ranged between highly, moderate, narrow, weak and non-active but, didn’t had effect on tested fungal isolates. Alternaria alternata and Microascus trigonosporus were chosen from the most potent antibacterial fungi to determine the antibacterial ingredients by gas chromatography-mass spectrometry (GC-MS) analysis from which seventeen and twenty nine compounds were identified, respectively. Original Research Article EL-Said et al.; AJBGE, 3(1): 1-12, 2020; Article no.AJBGE. 54815 2
Mental Health Status of Doctors and Nurses During COVID-19 Epidemic in China

Background: The sudden epidemic of COVID-19 in China caused attention globally. Health staff are in heavy workload and at high-risk infection. The aims of this study were to investigate the mental health status of health staff and to identify the key population of psychological intervention. Methods: Health staff were invited to attend an anonymous WeChat-based survey between Feb 17 to 24, 2020. Sample was collected based on a non-probability sampling procedure. Three mental health problems during the past week including psychological distress, anxious symptoms, and depressive symptoms were evaluated by WHO 20-item Self-Reporting Questionnaire (SRQ-20), the Zung Self-rating Anxiety Scale (SAS), and the Zung Self-rating Depression Scale (SDS) respectively. The characteristics of hospitals and participants were also collected in the survey. Findings: Totally 4679 doctors and nurses from 348 hospitals in 31 provinces of mainland China completed the survey. The prevalence of psychological distress, anxious symptoms, and depressive symptoms were 15‧9% (95% CI 14‧8-16‧9), 16‧0% (95% CI 15‧0-17‧1), and 34‧6% (95% CI 33‧2-35‧9). Those with middle age, being divorced or widowed, seldom or not living with family members, being a nurse, working at high-risk departments, having experiences of treatment for COVID-19 or other infectious diseases, from designated hospitals for COVID-19 treatment, non-infectious disease hospitals, and higher level hospitals had higher risk to have at least one of the mental health problems. Medical staff with three mental health problems (23‧2%) received less psychological help compared with those without any problem (35‧3%). Interpretation: Those with features of high-risk mental health problems should be set as priority for psychiatric interventions, especially when mental health professionals are not sufficient in China. Funding Statement: This project is an independent scientific research project approved by the Scientific Committee of Beijing Ditan Hospital Capital Medical University. Declaration of Interests: The authors declare no competing interests. Ethics Approval Statement: This survey was approved by the Ethical Committee of Beijing Ditan Hospital Capital Medical University (BJDTH) (JINGDILUNKE(2020)-(012)-01). All participants voluntarily attended this WeChat-based anonymous survey and were thus considered exempting from written informed consent.
Integración de la narración y la argumentación en la renarración de textos narrativos

The objective of this article is to analyse the presence of narrative structural elements of the history of a children's literary text in children's stories, analyse the argumentative schemes that they implement when they justify both the actions of the characters and their own positions on what happened in the story. Forty five students, 25 girls and 20 boys between 6 and 10 years old participated in this research (M = 8.10, SD = 0.9); from first to fifth grade of the elementary school of a school in the city of Bogota (Colombia). The corpus used in this report was composed of 1152 statements in 655 speaking turns. The quantitative analyses through chi-square account for significant differences for the mean of narrative structural elements, narrative categories and argumentative schema by grade level. The results are discussed highlighting that the use of narration and argumentation converges gradually and that these types of discourse together favour the re-tellings of narrative texts.