Miracle-dz/UniFAR-FTUs huggingface dataset:
The Role of Stratospheric Ozone in the Zonal and Seasonal Radiative Energy Balance of the Earth-Troposphere System

Abstract The role of ozone in the tropospheric-surface energy balance is discussed in the context of its latitudinally and seasonally varying modulation of solar and longwave energy fluxes. We analyze in detail the various radiative energy inputs to the stratosphere and the radiative fluxes from the stratosphere to the troposphere. To a very close approximation, on an annual and hemispherical mean, longwave emission from the stratosphere balances the absorbed radiant energy. The stratosphere absorbs about twice as much longwave radiation from the troposphere as it does solar radiation. About 20% of the longwave flux from the stratosphere to the troposphere is directly due to O2. A change in O3 concentrations perturbs the stratospheric and tropospheric-surface energy balances through a number of distinct mechanisms involving changes in solar and longwave fluxes and which are separated into direct effects due to the change of O3 and indirect effects due to the accompanying change of stratospheric temperatur.
Studies on the Parasitic Helminths of the North Central States. II. Studies on the Parasitic Helminths of the North Central States. II. Helminths of Voles ( Helminths of Voles (MicrotusMicrotus spp.) Preliminary Report spp.) Preliminary Report

The helminths of North American mouse-like rodents have received little study. Previous work has been based on low numbers of animals examined, and there has been little reference to the ecology involved. The purpose of this paper is to present data resulting from the examination of over 600 voles, with special reference to host-parasite relationships. Hall the nematodes parasitic in rodents, previous records of previously voles, in with the
The prevalence of molecular markers of resistance to sulfadoxine-pyrimethamine among pregnant women at first antenatal clinic attendance and delivery in the forest-savannah area of Ghana

Intermittent preventive treatment during pregnancy with sulfadoxine-pyrimethamine (IPTp-SP) is used to prevent malaria and associated unfavorable maternal and foetal outcomes in pregnancy in moderate to high malaria transmission areas. Effectiveness of IPTp-SP is, however, threatened by mutations in the Plasmodium falciparum dihydrofolate reductase (Pfdhfr) and dihydropteroate synthase (Pfdhps) genes which confer resistance to pyrimethamine and sulfadoxine, respectively. This study determined the prevalence of molecular markers of SP resistance among pregnant women in a high malaria transmission area in the forest-savannah area of Ghana. Genomic DNA was extracted from 286 P. falciparum-positive dried blood spots obtained from pregnant women aged ≥18 years (255 at first Antenatal Care (ANC) clinic visit and 31 at delivery from 2017 to 2019) using Chelex 100. Mutations in Pfdhfr and Pfdhps genes were detected using molecular inversion probes and next generation sequencing. In the Pfdhfr gene, single nucleotide polymorphisms (SNPs) were detected in 83.1% (157/189), 92.0% (173/188) and 91.0% (171/188) at codons 51, 59, and 108 respectively in samples collected at first ANC visit, while SNPs were detected in 96.6 (28/29), 96.6% (28/29) and 96.8% (30/31) in isolates collected at delivery. The Pfdhfr triple mutant N51I, C59R and S108N (IRN) was carried by 80.5% (128/159) and 96.5% (28/29) of the typed isolates collected at ANC visit and at delivery respectively. In the Pfdhps gene, SNPs were detected in 0.6% (1/174), 76.2% (138/181), 33.2% (60/181), 1.2% (2/174), 0% (0/183), and 16.6% (27/173) at codons 431, 436, 437, 540, 581 and 613 respectively in samples collected at ANC, and 0% (0/25), 72% (18/25), 40% (10/25), 3.6% (1/25), 0% (0/29) and 7.4% (2/27) in samples collected at delivery. Quadruple mutant Pfdhfr N51I, C59R, and S108N + Pfdhps A437G (IRN-GK) was present in 25.8% (33/128) and 34.8% (8/23) of isolates at ANC and at delivery respectively. Quintuple mutant alleles Pfdhfr N51I, C59R, and S108N + Pfdhps A437G and K540E (IRN-GE) were detected in 0.8% (1/128) and 4.4% (1/23) of samples collected at ANC and at delivery respectively. No mutations were identified at Pfdhfr codons 16 or 164 or Pfdhps 581. There is a high prevalence of Pfdhfr triple mutant P. falciparum infections among pregnant women in the study area. However, prevalence of the combined Pfdhfr/Pfdhps quadruple and quintuple mutants IRN-GK and IRN-GE respectively prior to commencement of IPTp-SP were low, and no Pfdhps A581G mutant was detected, indicating that SP is still likely to be efficacious for IPTp-SP in the forest-savannah area in the middle belt of Ghana.
A Concurrent Multiscale Detector for End-to-End Image Matching

This article focuses on end-to-end image matching through joint key-point detection and descriptor extraction. To find repeatable and high discrimination key points, we improve the deep matching network from the perspectives of network structure and network optimization. First, we propose a concurrent multiscale detector (CS-det) network, which consists of several parallel convolutional networks to extract multiscale features and multilevel discriminative information for key-point detection. Moreover, we introduce an attention module to fuse the response maps of various features adaptively. Importantly, we propose two novel rank consistent losses (RC-losses) for network optimization, significantly improving image matching performances. On the one hand, we propose a score rank consistent loss (RC-S-loss) to ensure that the key points have high repeatability. Different from the score difference loss merely focusing on the absolute score of an individual key point, our proposed RC-S-loss pays more attention to the relative score of key points in the image. On the other hand, we propose a score-discrimination RC-loss to ensure that the key point has high discrimination, which can reduce the confusion from other key points in subsequent matching and then further enhance the accuracy of image matching. Extensive experimental results demonstrate that the proposed CS-det improves the mean matching result of deep detector by 1.4%–2.1%, and the proposed RC-losses can boost the matching performances by 2.7%–3.4% than score difference loss. Our source codes are available at https://github.com/iquandou/CS-Net.
Cancer‐related stroke: Exploring personalized therapy strategies

Cancer and ischemic stroke are two common diseases that threaten human health and have become the main causes of death in the world. It is estimated that one‐in‐ten patients with ischemic stroke have concomitant cancer, and this incidence is expected to increase as improvements in medical technology extends the life expectancy of cancer patients.
Immunogenicity After a Heterologous BNT262b2 Versus Homologous Booster in Kidney Transplant Recipients Receiving 2 Doses of CoronaVac Vaccine: A Prospective Cohort Study

Background. Comparative studies of third heterologous doses following the CoronaVac vaccine against coronavirus disease 2019 (COVID-19) in kidney transplant recipients are lacking. Methods. This prospective, single-center cohort study included kidney transplant recipients without previous COVID-19. Patients received a third heterologous (BNT162b2 mRNA) or homologous dose at least 4 wk after 2 doses of the CoronaVac vaccine. Immunoglobulin G antibody response and seroprevalence for neutralizing anti–severe acute respiratory syndrome coronavirus 2 antibodies immediately before and 28 d after third doses were compared between the groups. Results. There were 307 patients in the heterologous group and 777 in the homologous group. Patients in the heterologous group were older (54 versus 50 y; P < 0.0001), with a longer time since transplant (11 versus 6 y; P < 0.0001). Immediately before the third dose, immunoglobulin G seroprevalence (36% versus 34%; P = 0.597) and antibody titers (246 versus 268 AU/mL; P = 0.279) were similar. After booster, seroconversion was higher in the heterologous group (49% versus 32%; P < 0.0001), resulting in a higher seroprevalence (67% versus 55%; P = 0.0003); however, 42% of all patients remained seronegative. Antibody titers after booster in seropositive patients were higher in the heterologous group (7771 versus 599 AU/mL; P < 0.0001). These results persisted after adjusting for confounding variables. Lastly, a similar proportion of patients became seropositive for neutralizing antibodies (98% versus 94%; P = 0.098). Conclusions. In kidney transplant recipients fully vaccinated with CoronaVac, a third dose with an mRNA vaccine produced a higher seroconversion rate and antibody titers than a third homologous dose. However, both boosters achieved equivalent seroprevalence for neutralizing antibodies. The high proportion of still seronegative patients indicates the need for alternative strategies of protection.
Green Leaf Volatiles - The forefront of Plant Responses Against Biotic Attack.

Green leaf volatiles (GLVs) are six-carbon volatile oxylipins ubiquitous in vascular plants. GLVs are produced from acyl groups in the biological membranes via oxygenation by a pathway-specific lipoxygenase (LOX) and subsequent cleavage reaction by hydroperoxide lyase (HPL). Because of the universal distribution of the ability to form GLVs, they have been anticipated to play a common role in vascular plants. While resting levels in intact plant tissues are low, GLVs are immediately synthesized de novo in response to stresses that disrupt the cell structure such as insect herbivory. This rapid GLV-burst is one of the fastest responses of plants to cell-damaging stresses; therefore, GLVs are the first plant-derived compounds encountered by organisms that interact with plants irrespective of whether the interaction would be competitive or friendly. GLVs must therefore be considered as important mediators between plants and those organisms that are interacting with them. GLVs can have direct effects by deterring herbivores and pathogens as well as indirect effects by attracting predators of herbivores, all the while other plants can eavesdrop on them and prepare their defenses, a process called priming. While the beneficial effects provided to plants by GLVs are often less dramatic and even complementary, the buildup of these tiny effects due to the multiple functions of GLVs can amass to levels that become substantially beneficial to plants. This review summarizes the current understanding of the spatiotemporal resolution of GLV-biosynthesis and GLV-functions and outlines how GLVs support the basic health of plants.
Outcome after resection arthroplasty or shortening oblique osteotomy of the lesser metatarsals combined with arthrodesis of the first metatarsophalangeal joint for severe rheumatoid forefoot deformities

Purpose We investigated objective and patient-reported outcomes after resection arthroplasty or shortening oblique osteotomy (SOO) of the lesser metatarsals combined with arthrodesis of the first metatarsophalangeal (MTP) joint for severe rheumatoid forefoot deformities. Methods 17 feet from 14 women (mean age, 67.8 years) underwent resection arthroplasty of the lesser metatarsal heads (MTH resection group), while 13 feet from nine women and two men (mean age, 68.7 years) underwent SOO of the lesser metatarsals (MTH preservation group). Arthrodesis of the first MTP joint was performed in all cases. Mean follow-up in the MTH resection and preservation groups was 25.0 and 21.3 months, respectively. Preoperative and postoperative clinical evaluation included Japanese Society for Surgery of the Foot (JSSF) scale and self-administered foot evaluation questionnaire (SAFE-Q) scores. Results Mean total JSSF scale significantly improved from 53.4 to 76.4 in the MTH resection group (p < .001) and from 50.1 to 74.2 in the MTH preservation group (p = .002). Pain and pain-related and shoe-related SAFE-Q subscale scores significantly improved after surgery in both groups. In the MTH resection group, recurrence of painful callosities and claw toe deformity was observed in four and three feet, respectively. In the MTH preservation group, one patient experienced recurrence of painful callosities and one underwent revision surgery for IP joint dislocation. Conclusion Resection arthroplasty or SOO of the lesser metatarsals combined with arthrodesis of the first MTP joint achieved significant improvement with respect to pain relief, deformity correction, and footwear comfort.
Social relationships and their associations with affective symptoms of women with breast cancer: A scoping review

Background Problems in affective and cognitive functioning are among the most common concurrent symptoms that breast cancer patients report. Social relationships may provide some explanations of the clinical variability in affective-cognitive symptoms. Evidence suggests that social relationships (functional and structural aspects) can be associated with patients’ affective-cognitive symptoms; however, such an association has not been well studied in the context of breast cancer. Purpose The purpose of this scoping review was to address the following question: What social relationships are associated with affective-cognitive symptoms of women with breast cancer? Methods This scoping review used the framework proposed by Arksey and O’Malley and PRISMA-Sc. Studies published by February 2022 were searched using four databases: MEDLINE (PubMed), Embase (Elsevier), PsycINFO (EBSCOhost), and Web of Science (Clarivate). All retrieved citations were independently screened and eligibility for inclusion was determined by study team members. Extracted data included research aims, design, sample, type and measures of social relationships (functional and structural), and the association between social relationships and affective-cognitive symptoms Results A total of 70 studies were included. Affective symptoms were positively associated with social support, family functioning, quality of relationships, social networks, and social integration, whereas the negative association was found with social constraints. Conclusion Our findings suggest positive social relationships may mitigate affective symptoms of women with breast cancer. Thus, health care providers need to educate patients about the importance of building solid social relationships and encourage them to participate in a supportive network of friends and family members.
Improvement in Clinical Outcomes and Access to Care With Pharmacist-Led Chronic Care Management Services at a Rural Family Medicine Clinic

Background: Chronic care management (CCM) can significantly impact the management of chronic diseases in rural patient populations. To date, few practice models have addressed its impact on clinical outcomes and access to care in rural practice settings. Objective: Implement a sustainable pharmacist-led CCM practice model while tracking clinical outcomes and healthcare access at a rural, medically underserved family medicine clinic. Methods: This study retrospectively examined data from the clinic’s CCM program from October 2020 through May 2021 and included total clinical encounters at three- and 6-months intervals, as well as changes in clinical outcomes like A1c and systolic blood pressure (SBP) at three- and 6-months intervals. Results: Over an 8-month period, 46 patients were enrolled in pharmacist-led CCM services. Those with a CCM encounter or office visit within 3 months of enrollment showed a mean A1c reduction of 1.07% after 3 months (95% CI −1.70 to −.44, P = .0016), while those with an encounter or office visit within 6 months of enrollment displayed a mean A1c reduction of 1.64% after 6 months (95% CI −2.35 to −.92, P < .001). There was a 73.8% increase in total clinical encounters in the 6 months after CCM enrollment compared to the 6 months preceding it, signifying increased access to care. Conclusion: Patients with CCM encounters or office visits within the first 3-6 months experienced statistically significant reductions in A1c. Moreover, total clinical encounters markedly increased in the 6 months after enrollment, allowing for more frequent engagement between ambulatory pharmacists and traditionally challenging rural patients.
Could red cell distribution width be used for predicting cardiac injury in neonates with COVID‐19?

Coronavirus disease 2019 (COVID‐19) can affect people of all age groups and it can occasionally cause life‐threatening clinical illnesses in immunologically immature populations, especially in newborns. High red cell distribution width (RDW) values were used as an early prognostic biomarker of some neonatal diseases. We aimed to determine the prognostic value of RDW in severe acute respiratory syndrome‐coronavirus‐2 (SARS‐CoV‐2) infected neonates.
Silvicultural Treatments

—Sustainable, ecologically-based management of pine/ fir forests requires silviculturists to integrate several treatments that emulate historic disturbance processes. Restoration prescriptions typically include cleaning or heavy understory thinning, improvement cutting to reduce the proportion of firs, and modified selection cutting to reduce overall stand density, leading to stands that are moderately open, primarily ponderosa pine, uneven-aged, and large-tree dominated.
How failure to falsify in high-volume science contributes to the replication crisis

The number of scientific papers published every year continues to increase, but scientific knowledge is not progressing at the same rate. Here we argue that a greater emphasis on falsification – the direct testing of strong hypotheses – would lead to faster progress by allowing well-specified hypotheses to be eliminated. We describe an example from neuroscience where there has been little work to directly test two prominent but incompatible hypotheses related to traumatic brain injury. Based on this example, we discuss how building strong hypotheses and then setting out to falsify them can bring greater precision to the clinical neurosciences, and argue that this approach could be beneficial to all areas of science.
Towards Ethical AI: Empirically Investigating Dimensions of AI Ethics, Trust Repair, and Performance in Human-AI Teaming

OBJECTIVE Determining the efficacy of two trust repair strategies (apology and denial) for trust violations of an ethical nature by an autonomous teammate. BACKGROUND While ethics in human-AI interaction is extensively studied, little research has investigated how decisions with ethical implications impact trust and performance within human-AI teams and their subsequent repair. METHOD Forty teams of two participants and one autonomous teammate completed three team missions within a synthetic task environment. The autonomous teammate made an ethical or unethical action during each mission, followed by an apology or denial. Measures of individual team trust, autonomous teammate trust, human teammate trust, perceived autonomous teammate ethicality, and team performance were taken. RESULTS Teams with unethical autonomous teammates had significantly lower trust in the team and trust in the autonomous teammate. Unethical autonomous teammates were also perceived as substantially more unethical. Neither trust repair strategy effectively restored trust after an ethical violation, and autonomous teammate ethicality was not related to the team score, but unethical autonomous teammates did have shorter times. CONCLUSION Ethical violations significantly harm trust in the overall team and autonomous teammate but do not negatively impact team score. However, current trust repair strategies like apologies and denials appear ineffective in restoring trust after this type of violation. APPLICATION This research highlights the need to develop trust repair strategies specific to human-AI teams and trust violations of an ethical nature.
Sources of information used by elite distance running coaches for selection decisions

Talent identification and selection are critical components of competitive sport success. Despite the time, effort, and resources invested, the accuracy of selection decisions remains generally poor. While much of the scholarship in this area has focused on the factors discriminating skilled and less-skilled individuals, limited research exists on what information is used in the decision-making process for athlete selection. The current study seeks to gain a better understanding of the information used by elite distance running coaches when forming judgements for athlete selection. Ten semi-structured interviews with elite distance running coaches from across Canada were transcribed and analyzed using inductive thematic analysis. It was interpreted that coaches mainly gather information using their coach’s eye to determine an athlete’s ‘fit’ to the team. Coaches also use more objective information such as race times and movement analyses to assess performance and judge future ‘potential’. As well, the decisions were believed to be influenced by situational considerations at the time of the selection procedure. Specifically, these considerations affecting a coach’s selection included length of time to make a decision, personal limitations in decision-making abilities, and team circumstances. Interestingly, coaches recognized limitations in their selection practices and procedures and discussed some of their personal and system-level biases, highlighting their awareness of potential selection inefficiencies/inaccuracies. Overall, distance running coaches used a variety of techniques to gather information before a selection was made, relying on both subjective and objective information for crafting judgments. Findings are discussed in relation to implications for coaches, sport organizations, and talent identification and selection programs.
Associations Between Changes in Depression/Anxiety Symptoms and Fall Worry Among Community-Dwelling Older Adults

Using the 2019 and 2020 National Health and Aging Trend Study, we examined the association between fall worry and changes in depression/anxiety symptoms among community-dwelling older adults age 70+ (N = 3333). Past-month fall worry in 2020 included any fall worry (30.9%) and activity-limiting fall worry (34.0% of those with any fall worry). Changes in depression/anxiety symptoms referred to an increase or decrease in the Patient Health Questionnaire-4 symptom categories between 2019 and 2020. Those with fall worry, compared to those without, had significantly higher rates of moderate/severe depression/anxiety symptoms in 2019 and increased depression/anxiety symptoms over time. Multivariable analysis results show that increased depression anxiety symptoms were associated with higher risks of any and activity-limiting fall worry, controlling for previous year’s fall worry, fall incidents, and other health- and fall-related covariates. Older adults need to be screened for both depression/anxiety and fall worry. Effective psychosocial and behavioral interventions for both conditions are needed.