Occurring GermLine Mutations of the BRCA 1 Gene in Ovarian Cancer Families from Russia

Berman DB, Costalas J, Schultz DC, Grana G, Daly M, Godwin AK (1996) A common mutation in BRCA2 that predisposes to a variety of cancers is found in both Jewish Ashkenazi and non-Jewish individuals. Cancer Res 56:3409-3414 Breast Cancer Information Core (1997) http:/www.nchgr. nih . gov/Intramuralresearch/Labtransfer/Bic Couch FJ, Farid LM, DeShano ML, Tavtigian SV, Calzone K, Campeau L, Peng Y, et al (1996) BRCA2 germline mutations in male breast cancer cases and breast cancer families. Nat Genet 13:123-125 Friedman LS, Gayther SA, Kurosaki T, Gordon D, Noble B, Casey G, Ponder BAJ, et al (1997) Mutation analysis of BRCA1 and BRCA2 in male breast cancer population. Am J Hum Genet 60:313-319 Gayther SA, Mangion J, Russel P, Seal S, Barfoot R, Ponder BAJ, Stratton MR, et al (1997) Variation of risks of breast and ovarian cancer associated with different germline mutations of the BRCA2 gene. Nat Genet 15:103-105 Gayther SA, Warren W, Mazoyer S, Russel PA, Harrington PA, Chiano M, Seal S. et al (1995) Germline mutations of the BRCA1 gene in breast/ovarian cancer families: evidence for a genotype/phenotype correlation. Nat Genet 11:428433 Hogervorst FBL, Cornelis RS, Bout M, van Vliet M, Oosterwijk JC, Olmer R, Bakker B, et al (1995) Rapid detection of BRCA1 mutations by the protein truncation test. Nat Genet 10:208-212 Johannesdottir G, Gudmundsson J. Berghthorsson JT, Arason A, Agnarsson BA, Eiriksdottir G, Johannsson OT, et al (1996) High prevalence of the 999de15 mutation in Icelandic breast and ovarian cancer patients. Cancer Res 56:36633665 Keen J, Lester D, Inglehern C, Curtis A, Bhattacharya S (1991) Rapid detection of single base mismatches as heteroduplexes on Hydrolink gels. Trends Genet 7:5 Neuhausen SL, Gilewski T. Norton L, Tran T, McGuire P. Swensen J, Hampel H. et al (1996) Recurrent BRCA2 6174delT mutations in Ashkenazi Jewish women affected by breast cancer. Nat Genet 13:126-128 Oddoux C, Streuwing JP, Clayton CM, Neuhausen S, Brody LC, Kaback M, Haas B, et al (1996) The carrier frequency of the BRCA2 6174delT mutation among Ashkenazi Jewish individuals is approximately 1%. Nat Genet 13:188-190 Phelan CM, Lancaster JM, Tonin P, Gumbs C, Cochran C, Carter R, Ghadirian P. et al (1996) Mutation analysis of the BRCA2 gene in 49 site-specific breast cancer families. Nat Genet 13:120-122 Roa BB, Boyd AA, Volcik K, Richards CS (1996) Ashkenazi Jewish population frequencies for common mutations in BRCA1 and BRCA2. Nat Genet 14:185-187 Serova OM, Mazoyer S, Puget N, Dubois V, Tonin P, Shugart YY, Goldgar D, et al (1997) Mutations in BRCA1 and BRCA2 in breast cancer families: are there more breast cancer-susceptibility genes? Am J Hum Genet 60:486-495 Takahashi H, Chiu H-C, Bandera CA, Behbakht CA, Liu PC, Couch FJ, Weber BL, et al (1996) Mutations of the BRCA2 gene in ovarian carcinomas. Cancer Res 56:2738-2741 Tassabehji M, Read AP, Newton VE, Harris R, Balling R, Gruss P, Strachan T (1992) Waardenburg's syndrome patients have mutations in the human homologue of the Pax3 paired box gene. Nature 355:635-636 Tavtigian SV, Simard J, Rommens J, Couch F, Shattuck-Eidens D, Neuhausen S, Merajver S, et al (1996) The complete BRCA2 gene and mutations in chromosome 13q-linked kindreds. Nat Genet 12:333-337 Thorlacius S. Olafsdottir G, Tryggvadottir L, Neuhausen S, Jonasson JG, Tavtigian SV, Tulinius H, et al (1996) A single BRCA2 mutation in male and female breast cancer families from Iceland with varied cancer phenotypes. Nat Genet 13: 117-119 Tonin P, Weber B. Offit K, Couch F. Rebbeck T, Neuhausen S. Godwin A, et al (1996) Frequency of recurrent BRCA1 and BRCA2 mutations in Ashkenazi Jewish breast cancer families. Nat Med 2:1174-1183 van der Luijt R, Khan PM, Vasen H, van Leeuwen C, Tops C, Roest P, den Dunnen J. et al (1994) Rapid detection of translation-terminating mutations at the adenomatous polyposis coli (APC) gene by direct protein truncation test. Genomics 20:1-4 White MB, Carvalho M, Derse D, O'Brien SJ, Dean M (1992) Detecting single base substitutions as heteroduplex polymorphisms. Genomics 12:301-306 Wooster R, Bignell G, Lancaster J, Swift S, Seal S, Mangion J, Collins N, et al (1995) Identification of the breast cancer gene BRCA2. Nature 378:789-791 Wooster R. Neuhausen SL, Mangion J, Quirk Y, Ford D, Collins N. Nguyen K, et al (1994) Localization of a breast cancer susceptibility gene, BRCA2, to chromosome 13q1213. Science 265:2088-2090