Miracle-dz/UniFAR-FTUs huggingface dataset:
Modeling Actual Evapotranspiration with MSI-Sentinel Images and Machine Learning Algorithms

The modernization of computational resources and application of artificial intelligence algorithms have led to advancements in studies regarding the evapotranspiration of crops by remote sensing. Therefore, this research proposed the application of machine learning algorithms to estimate the ETrF (Evapotranspiration Fraction) of sugar can crop using the METRIC (Mapping Evapotranspiration at High Resolution with Internalized Calibration) model with data from the Sentinel-2 satellites constellation. In order to achieve this goal, images from the MSI sensor (MultiSpectral Instrument) from the Sentinel-2 and the OLI (Operational Land Imager) and TIRS (Thermal Infrared Sensor) sensors from the Landsat-8 were acquired nearly at the same time between the years 2018 and 2020 for sugar cane crops. Images from OLI and TIR sensors were intended to calculate ETrF through METRIC (target variable), while for the MSI sensor images, the explanatory variables were extracted in two approaches, using 10 m (approach 1) and 20 m (approach 2) spatial resolution. The results showed that the algorithms were able to identify patterns in the MSI sensor data to predict the ETrF of the METRIC model. For approach 1, the best predictions were XgbLinear (R2 = 0.80; RMSE = 0.15) and XgbTree (R2 = 0.80; RMSE = 0.15). For approach 2, the algorithm that demonstrated superiority was the XgbLinear (R2 = 0.91; RMSE = 0.10), respectively. Thus, it became evident that machine learning algorithms, when applied to the MSI sensor, were able to estimate the ETrF in a simpler way than the one that involves energy balance with the thermal band used in the METRIC model.
Management of Advanced Pancreatic Cancer through Stromal Depletion and Immune Modulation

Pancreatic cancer is one of the leading causes of cancer-related deaths worldwide. Unfortunately, therapeutic gains in the treatment of other cancers have not successfully translated to pancreatic cancer treatments. Management of pancreatic cancer is difficult due to the lack of effective therapies and the rapid development of drug resistance. The cytotoxic agent gemcitabine has historically been the first-line treatment, but combinations of other immunomodulating and stroma-depleting drugs are currently undergoing clinical testing. Moreover, the treatment of pancreatic cancer is complicated by its heterogeneity: analysis of genomic alterations and expression patterns has led to the definition of multiple subtypes, but their usefulness in the clinical setting is limited by inter-tumoral and inter-personal variability. In addition, various cell types in the tumor microenvironment exert immunosuppressive effects that worsen prognosis. In this review, we discuss current perceptions of molecular features and the tumor microenvironment in pancreatic cancer, and we summarize emerging drug options that can complement traditional chemotherapies.
Analysis of the ZNT8, GAD65, HLA-DQA1, HLA-DQB1, and C-peptides in Indonesian children with type 1 diabetes mellitus

Autoimmune reaction in Type 1 Diabetes Mellitus (T1DM) is caused by genetic and environmental factors. The genes HLA-DQA1 and HLA-DQB1 are strongly associated with T1DM. Other established markers of T1DM were Zinc Transporter 8 Antibody (ZnT8), Glutamic Acid Decarboxylase Antibody-65 (GAD65), and C-peptide. This study aims to analyze ZnT8, GAD65, HLA-DQA1, HLA-DQB1, and C-peptide in Indonesian children with T1DM. A cross-sectional study of T1DM children was conducted in Dr. Soetomo Hospital, Indonesia. ZnT8, GAD65, HLA-DQA1, HLA-DQB1, and C-peptide were examined with an ELISA kit. Mann-Whitney test was performed with a significant value of p<0.05. A total of 62 participants consisting of 31 children for each group were enrolled. The prevalence of ZnT8, GAD65, and C-peptide in T1DM patients was 77.4%, 90.3%, and 87.1%. There are 74% of T1DM children had two positive antibodies and 55% had two positive HLA peptides. There was no difference in HLA-DQA1 and HLA-DQB1 peptides between T1DM and control groups (p=0.12; p=0.19). Meanwhile, the comparison between ZnT8, GAD65, and C-Peptide values between T1DM and control groups shows a significant difference (p<0.05). HLA-DQA1 peptide value was higher in T1DM children and HLA-DQB1 peptide value was higher in non-T1DM children.
An A Posteriori Error Estimator for a Non Homogeneous Dirichlet Problem Considering a Dual Mixed Formulation

In this paper, we describe an a posteriori error analysis for a conforming dual mixed scheme of the Poisson problem with non homogeneous Dirichlet boundary condition. As a result, we obtain an a posteriori error estimator, which is proven to be reliable and locally efficient with respect to the usual norm on H(div;Omega) x L^2(Omega). We remark that the analysis relies on the standard Ritz projection of the error, and take into account a kind of a quasi-Helmholtz decomposition of functions in H(div;Omega), which we have established in this work. Finally, we present one numerical example that validates the well behavior of our estimator, being able to identify the numerical singularities when they exist.
Blood Pressure Target in Type 2 Diabetes Mellitus

The prevalence of diabetes mellitus continues to increase worldwide, and it is a well-established cardiovascular risk factor. Hypertension is also an important cardiovascular risk factor to be controlled and is common among patients with diabetes mellitus. Optimal blood pressure (BP) goals have been the subject of great debate in the management of hypertension among patients with diabetes mellitus. This review provides detailed results from randomized controlled trials and meta-analyses of clinical outcomes according to the target BP in patients with type 2 diabetes mellitus. In addition, the target BP in patients with diabetes mellitus recommended by different guidelines was summarized and presented. A target BP of <140/90 mm Hg is recommended for patients with hypertension and diabetes mellitus, and BP should be controlled to <130/80 mm Hg in patients with diabetes mellitus who have high-risk clinical features. We hope that this review will be helpful to clinicians and patients by promoting the understanding and appropriate application of BP control in the comprehensive management of patients with diabetes mellitus.
Non-Ionizing Radiation Measurements for Trajectography Radars

This work presents a Non-Ionizing Radiation (NIR) measurement campaign and proposes a specific measurement method for trajectography radars. This kind of radar has a high gain narrow beam antenna and emits a high power signal. Power density measurements from a C-band trajectography radar are carried out using bench equipment and a directional receiving antenna, instead of the commonly used isotropic probe. The measured power density levels are assessed for compliance test via comparison with the occupational and general public exposure limit levels of both the International Commission on Non-Ionizing Radiation Protection (ICNIRP) and the Brazilian National Telecommunication Agency (Anatel). The limit for the occupational public is respected everywhere, evidencing the safe operation of the studied radar. However, the limit for the general public is exceeded at a point next to the radar’s antenna, showing that preventive measures are needed.
Observable Symptoms of Anxiety in Individuals with Fragile X Syndrome: Parent and Caregiver Perspectives

Caregiver reports, clinical observations, and diagnostic assessments indicate that most individuals with fragile X syndrome experience high levels of chronic anxiety. However, anxiety is a challenging endpoint for outcome measurement in FXS because most individuals cannot reliably report internal emotional or body states. A comprehensive survey of the presence, frequency, and duration of anxiety-related symptoms and questions to elicit open-ended responses was completed by caregivers of 456 individuals with FXS, ages 2–81 years (87 female, 369 male) and 24 female and 2 male FXS self-advocates ages 15–66 years. Caregivers reported classic behavioral indicators of anxiety, such as avoidance, irritability, motor agitation, and physiological symptoms, as well as behavioral features in FXS such as repetitive behavior, aggression, and self-injury. Self-advocate accounts largely paralleled caregiver data. Factor analyses yielded four factors: (1) increased irritability, aggression, and self-injury; (2) increased physical movement, nervous activity, and restlessness; (3) physical and physiological features of anxiety; and (4) internalizing and gastrointestinal symptoms. Caregivers are capable of observing and reporting behaviors that are valid indicators of anxious states that are usually reported in self-report standardized assessments. These results support the development of an anxiety measure for FXS that minimizes problems with rater inference.
Optimization of Oil Yield from the Macro Algae Spirogyra by Solvent Extraction Process Using RSM and ANN

The present work was done to optimize the process parameters of the oil extraction from the algae species spirogyra by using n-hexane as the solvent using the Soxhlet apparatus. The response surface methodology (RSM) and artificial neural network (ANN) were employed to optimize the particle size of the algae powder, dryness level of the algae powder, solid to solvent ratio, reaction time, and extraction temperature of the oil extraction process. Also, the physiochemical properties of the extracted oil were investigated. The comparative evaluation was done between the RSM and ANN models to select the more precise and accurate model. The coefficient of determination, R 2 of 98.92%, and the mean absolute percentage deviation (MAPD) of 0.492% for ANN revealed that the current model created with a network topology of 3 : 11 : 1 with tansig (hyperbolic tangent sigmoid) transfer function in the input layer and purelin (pure linear) transfer function in the output layer trained with trainlm (Levenberg–Marquardt) algorithm found to provide the optimal solution with better accuracy in prediction of the output. The physicochemical properties investigated, such as heating value, flashpoint, density, viscosity, iodine number, acid value, saponification value, and cetane index, showed that the extracted oil from the algae spirogyra species can be used as an alternative fuel.
The Bem Sex-Role Inventory: Proposal of a short version in Spanish

The study objective was to examine the factorial structure, reliability and to provide some evidence for validity of the Spanish version of the Bem Sexual Roles Inventory (BSRI), which assesses self-description in terms of gender traits. A sample of 2,672 Spanish participants, heterosexual adults (1,289 men, 1,383 women) distributed into four age groups (18-25, 26-35, 36-55, 56 years or more), completed a Spanish 40-item version of BSRI. An 8-item scale is proposed with a two-dimensional structure: Masculinity (M) and Femininity (F). Both factors present adequate reliabi-lity. Regarding evidence for validity, men (vs. women) scored higher in M, and women (vs. men) in F. The M scores were higher for the participants aged less than 56 years. No differences were found in the F scores among age groups. We discuss the usefulness of this measure to assess interindividual differences, across sex and age, in the self-attribution of traditional gender traits. El objetivo del estudio fue examinar la estructura factorial, la confiabilidad y proporcionar alguna evidencia de validez de la versión en español del Inventario de Roles Sexuales de Bem (BSRI), que evalúa la autodescripción en términos de rasgos de género. Una muestra de 2.672 participantes españoles, adultos heterosexuales (1.289 hombres, 1.383 mujeres) distribuidos en cuatro grupos de edad (18-25, 26-35, 36-55, 56 años o más), completó una versión en español de 40 ítems del BSRI. Se propone una escala de 8 ítems con estructura bidimensional: Masculinidad (M) y Feminidad (F). Ambos factores presentan una fiabilidad adecuada. Con respecto a la evidencia de validez, los hombres (vs. las mujeres) obtuvieron puntuaciones más altas en M y las mujeres (vs. los hombres) en F. Las puntuaciones M fueron más altas para los participantes menores de 56 años. No se encontraron diferencias en las puntuaciones F entre grupos de edad. Discutimos la utilidad de esta medida para evaluar las diferencias interindividuales, según el sexo y la edad, en la autoatribución de los rasgos de género tradicionales.
Impact of Cassava Starch Varieties on the Physiochemical Change during Enzymatic Hydrolysis

The enzymatic modification of starch extends its industrial use to flavor delivery and probiotic encapsulants, among other uses. However, it is not known how starch from different cassava varieties responds to enzymatic hydrolysis. Starches from two Ecuadorian cassava varieties (INIAP 650, an edible starch, and INIAP 651, an industrial starch) were partially modified at three enzymatic hydrolysis degrees (0%, 30%, and 50%), and their physicochemical properties were assessed. The structural analysis revealed that both varieties showed progressive structural damage as hydrolysis increases, probably due to exo-hydrolysis. However, deeper pores were observed in INIAP 651 with the SEM analysis. The crystallinity percentage obtained by XRD analyses remained constant in INIAP 651 and decreased (by 26%) in INIAP 650 (p < 0.05). In addition, the amylose–lipid complex index in INIAP 650 remained constant, while INIAP 651 increased (p < 0.05) at 30% hydrolysis (by 93%). In both varieties, hydrolysis increased (p < 0.05) the water holding capacity (WHC) (by 10–14%) and the water binding capacity (WBC) (by 16%), but 50% hydrolysis of INIAP 650 was needed to significantly affect these properties. No differences were observed in the varieties’ thermal properties. Regarding the rheological properties, the variety did not influence the changes in the storage module (G′) and the loss modulus (G″) with the hydrolysis (p > 0.05). However, the phase angle decreased significantly (p < 0.05) with the hydrolysis, being higher in the INIAP 650 variety than in the INIAP 651 variety. In general, the results indicate that the variety affects the response of the starch granule to enzymatic hydrolysis (noticeable in the principal component analysis, PCA) and opens up the possibility to modulate starch properties.
Tableau systems for the modal μ-calculus

The main content of this thesis concerns a tableau method for solving the satisfiability problem for the modal μ-calculus. A sound and complete tableau system for the modal μ-calculus is given. Since every tableau in such tableau system is finite and bounded by the length of the formula, the tableau system may be used as a decision procedure for determining the satisfiability of the formula. An alternative proof of the small model property is obtained: every satisfiable formula has a model of size singleexponential in the length of the formula. Contrary to known proofs in literature, the results presented here do not rely on automata theory. Two simplifications of the tableau system are given. One is for the class of aconjunctive formulae. The resulting tableau system has been used to prove the completeness of Kozen’s axiomatisation with respect to the aconjunctive fragment of the modal μcalculus. Another is for the formulae in the class Πμ2 . In addition to the tableau method, the thesis explores some model-surgery techniques with the aim that such techniques may be used to directly prove the small model theorem. The techniques obtained so far have been used to show the small model property for Πμ2 -formulae and for formulae with linear models.
Hydrogen-Rich Water as a Novel Therapeutic Strategy for the Affective Disorders Linked with Chronic Neuropathic Pain in Mice

Neuropathic pain manifested with allodynia and hyperalgesia usually becomes a chronic condition accompanied with mood disorders. Clinical therapies for neuropathic pain are still unsatisfactory with notable side effects. Recent studies have reported the protective role of molecular hydrogen (H2) in different diseases including neurological disorders, such as Alzheimer’s as well as its antidepressant activities in animals with chronic stress. This study explored the effects of treatment with hydrogen-rich water (HRW) in male mice with neuropathic pain induced by the chronic constriction of the sciatic nerve (CCI) and the accompanying affective deficits. The likely pathways implied in the HRW analgesic activity, as well as the interaction between heme oxygenase 1 (HO-1) enzyme and H2 during neuropathic pain were also studied. The results showed: (i) the inhibitory effects of the repetitive treatment with HRW on the allodynia and hyperalgesia provoked by CCI; (ii) the anxiolytic and antidepressant actions of HRW in animals with neuropathic pain; (iii) the contribution of the antioxidant enzymes (HO-1 and NAD(P)H: quinone oxidoreductase 1) and the ATP sensitive potassium channels in the painkiller activities of HRW during neuropathic pain; (iv) a positive interaction between the HO-1 and H2 systems in inhibiting the CCI-induced neuropathy; and (v) the antioxidant, antinociceptive, anti-inflammatory and/or antiapoptotic features of HRW treatment in the dorsal root ganglia and/or amygdala of sciatic nerve-injured mice. This study demonstrates new protective actions of H2 and suggests that treatment with HRW might be an interesting therapeutic strategy for chronic neuropathic pain and its associated mood disorders.
Numerical behaviour of Toeplitz solutions

The numerical behavior of the order-recursive algorithms for the solution of a number of typical Toeplitz systems is studied. Use is made of a novel methodology that gives a direct interpretation of the positive definiteness that leads to the explicit computation of the minimum absolute bounds of the 1-step and l-step-ahead linear predictors. Ill-conditioning is discussed, and an algorithmic scheme with improved numerical behavior is given for the l-step-ahead LP case. It is proved that the Levinson algorithm, when it is used for the solution of the least-squares finite-impulse-response filtering problem, manifests a fundamentally different numerical behavior than when it is used for the l-step-ahead problem. <<ETX>>
Comparative Study of Conventional Inverted ILM Flap Covering and ILM Flap Filling Technique in Idiopathic Macular Hole Treatment: A Meta-Analysis and Systematic Review

Objective This meta-analysis was performed to evaluate the anatomical efficacy and functional improvement of the conventional inverted internal limiting membrane (ILM), flap covering technique, and ILM flap filling technique for patients with idiopathic macular hole (MH). Methods Literature from Pubmed, Embase, Cochrane Central Register of Controlled Trials, and Web of Science were comprehensively retrieved. The primary outcomes included the MH closure rate and postoperative best-corrected visual acuity (BCVA). The secondary outcomes were the proportion of external limiting membrane (ELM) and ellipsoid zone (EZ) defect recovery. Pooled odds ratios (ORs), weighted mean differences (WMDs), and 95% confidence intervals (CIs) were calculated using STATA 17.0 software. Results 7 studies that contained 139 eyes in the inverted ILM flap covering group and 121 eyes in the ILM flap filling group were selected. Pooled data suggested that the surgical treatment resulted in an overall MH closure rate of up to 97.12% (135/139 eyes) in the inverted ILM flap covering group and 99.17% (120/121 eyes) in the filling group, with no significant difference between the 2 groups (OR = 1.98, 95% CI: 0.55 to 7.09, and P=0.29). Similarly, the 2 techniques demonstrated equal effectiveness on the anatomical closure in MH with the average diameter smaller than 650 μm (OR = 2.17, 95% CI: 0.48 to 9.77, and P=0.31) and larger than 650 μm (OR = 1.58, 95% CI: 0.14 to 17.37, and P=0.71). However, compared with the filling technique, the inverted ILM flap covering technique was superior in postoperative BCVA (WMD = 0.11, 95% CI: 0.04 to 0.18, and P=0.0017) and presented a significantly higher proportion of reconstitution of ELM (OR = 0.02, 95% CI: 0.00 to 0.08, and P < 0.0001) and EZ (OR = 0.11, 95% CI: 0.04 to 0.32, and P=0.0001). Conclusion The inverted ILM flap covering technique was associated with the superior reconstitution of outer layers of the retina, including ELM and EZ, and more improvement in postoperative BCVA than the ILM flap filling technique.
Transverse Weitzenb\"ock formulas and curvature dimension inequalities on Riemannian foliations with totally geodesic leaves

We prove a family of new Weitzenb\"ock formulas on a Riemannian foliation with totally geodesic leaves. These Weitzenb\"ock formulas are naturally parametrized by the canonical variation of the metric. As a consequence, under natural geometric conditions, the horizontal Laplacian satisfies a generalized curvature dimension inequality. Among other things, this curvature dimension inequality implies Li-Yau estimates for positive solutions of the horizontal heat equation and a sub-Riemannian Bonnet-Myers compactness theorem whose assumptions only rely on the intrinsic geometry of the horizontal distribution.
The transformative virtual experience paradigm: the case of Airbnb’s online experience

Purpose This research paper aims to explore Airbnb’s online experience initiative, which has sparked a new wave of virtual tourism to improvise a large assortment of experiential activities through cyberspace. It works to answer questions pertinent to the type of virtual experiences tourists seek and how these experiences could fulfill tourist needs, thereby rendering favorable socio-mental outcomes through experiences encountered. Design/methodology/approach Drawing on travel experience and transformative tourism theoretical tenets, this qualitative inquiry used data collected from social media posts from virtual tourists. Findings Results reveal four major themes of online experiences – hedonism, attention restoration, social relatedness and self-exaltation – that encompass 12 experiential categories. They further underscore four types of transformative mechanisms pinpointing hedonic well-being, environmental-mastery well-being, social well-being and eudaimonic well-being. Research limitations/implications Research findings demonstrate how Airbnb exercised marketing agility during severe environmental plight; while expediting strategic initiatives that offer tourists and residents alike a means to reengage in leisure and travel activities at home. They also salvage the peer-to-peer community by turning accommodation hosts into online experience ambassadors. Originality/value The contribution of this inquiry lies in assessing virtual experiences and reconnecting how different cyber experiences can meet an array of tourist needs. This study further highlights the transformative virtual experience paradigm to lay the necessary theoretical foundation for future research on virtual transformative tourism. This research goes beyond the common understanding of transformative tourism that relies merely on corporeal encounters. From a practical point of view, this study brings light to a novel concept – sharing experience economy – that incorporates the nuances between sharing economy and experience economy.
Curvature Gradient Driving Droplets in Fast Motion

Earlier works found out spontaneous directional motion of liquid droplets on hydrophilic conical surfaces, however, not hydrophobic case. Here we show that droplets on any surface may take place spontaneous directional motion without considering contact angle property. The driving force is found to be proportional to the curvature gradient of the surface. Fast motion can be lead at surfaces with small curvature radii. The above discovery can help to create more effective transportation technology of droplets, and better understand some observed natural phenomena.