Miracle-dz/UniFAR-FTUs huggingface dataset:
Hubungan merokok dengan saturasi oksigen pada pegawai di fakultas kedokteran universitas Sam Ratulangi Manado

Abstract: Smoking is an overt behavior in which smokers inhale tobacco rolls. The degree of smoking can be determined based on the Brinkman index. Global Adults Tobacco Survey (GATS) estimates there are currently 7.9 billion adults who are actively smoking and 3.5 billion people are exposed to secondhand smoke in the workplace. This research aims to identify oxygen saturation of smokers and the correlation between smoking and oxygen saturation of administration staffs in the Medical Faculty of Sam Ratulangi University Manado. This research was a cross sectional study that was conducted on 30 administration staffs at the Faculty of Medicine, University of Sam Ratulangi. The correlation analysis was carried out using Kruskall-Wallis. Most respondents were mild smokers (63.33%) with the average oxygen saturation 98.37. Moderate Smokers have an average oxygen saturation of 97.86, and heavy smokers 96.25. All respondents had an average oxygen saturation of 97.97. All respondents are still categorized as having normal oxygen saturation (95-100%). Conclusion: There is a significant correlation between smoking and oxygen saturation. The more severe the degree of smoking, the lower level of oxygen saturation obtained in the blood. Keywords: smoking, oxygen saturation, administration staff. Abstrak: Merokok merupakan overt behavior dimana perokok menghisap gulungan tembakau. Derajat merokok dapat ditentukan berdasarkan Index Brinkman. Global Adults Tobacco Survey (GATS) memperkirakan terdapat 7,9 milyar orang dewasa saat ini perokok aktif dan 3,5 milyar orang terpapar asap rokok di tempat kerja. Penelitian ini bertujuan untuk mengetahui saturasi oksigen pada perokok dan hubungan merokok dengan saturasi oksigen pada pegawai di Fakultas Kedokteran Universitas Sam Ratulangi Manado. Penelitian ini bersifat observasional analitik dengan rancangan penelitian potong lintang yang dilakukan pada 30 pegawai di Fakultas Kedokteran Universitas Sam Ratulangi Manado dengan uji statistik Kruskal-Wallis. Penelitian ini memiliki nilai p < 0,05. Responden terbanyak adalah perokok derajat ringan (63,33%) dengan saturasi oksigen rata-rata 98,37. Perokok derajat sedang memiliki saturasi oksigen rata-rata 97,86 sedangkan perokok derajat berat 96,25. Seluruh responden memiliki saturasi oksigen rata-rata 97,97. Seluruh responden masih termasuk kategori saturasi oksigen baik (95-100%). Simpulan: Terdapat hubungan yang signifikan antara merokok dengan saturasi oksigen. Semakin berat derajat merokok maka semakin rendah kadar saturasi oksigen dalam darah. Kata kunci: merokok, saturasi oksigen, pegawai.
Invasive Aspergillosis in Patients Treated With Ibrutinib

The Bruton’s tyrosine kinase (BTK) inhibitor ibrutinib has revolutionized the treatment of chronic lymphocytic leukemia (CLL) yielding unprecedented progression-free and overall survival rates in most CLL populations. Based on these data, ibrutinib has been widely approved for treatment of CLL and evaluated in various other B-cell malignancies leading to the approval in Waldenström’s macroglobulinaemia (WM) and mantle cell lymphoma (MCL). Infections are a common complication in the natural course of CLL. However, they are mostly attributable to defects in T-cell function and humoral immunity. BTK mediates BCR signaling and thereby regulates Bcell activation, differentiation, cell-mediated interaction, and survival. It is crucial for development and function of the adaptive immunity: mutations in the encoding gene area result in
THE MEDIATOR ROLE OF INNOVATION BETWEEN UNIVERSITY-INDUSTRY COLLABORATION AND FIRM PERFORMANCE

University-industry collaboration is a matter that has been dealt with for many years in the literature, in addition to that it has a very long history. The reason why it is still attracted and researched by scholars is that the relationship between these two dynamic and powerful structures is also dynamic and their effects are strong enough not only for themselves but also for the region and even for the nation. Such that, governments support this relationship with various incentives nowadays. The aim of this study is to contribute to the related literature by investigating the mediator role of product and process innovation in the relationship between UIC and firm performance. By studying 90 firms, we found that UIC affects product and process innovation. We also found that product and process innovation influence firm performance. Furthermore, this study reveals that product and process innovation fully mediates the relationship between UIC and firm performance.
Effects of muscle energy technique for quadratus lumborum on respiratory muscle strength in patients with breast cancer

Introduction: Breast cancer is a major cause of morbidity and mortality, leading to functional deficiencies in ventilation, muscle performance, balance and posture.Objective: To describe the effects of the muscle energy technique (MET) for quadratus lumborum on maximal inspiratory pressure (MIP) and maximal expiratory pressure (MEP) in patients with stage I and II breast cancer.Materials and methods: Quasi-experimental study with a pretest-posttest design conducted in 10 patients treated at a highly specialized healthcare center in Bogotá. Physical therapy assessment and three physiotherapy sessions with the MET to measure MIP and MEP were carried out before and after the intervention using a respiratory pressure meter.Results: The average MIP was 41% of the reference value at the beginning of the intervention, which increased to 69% at the end of the sessions. On the other hand, the initial average MEP was 33%, while the post-intervention average MEP was 51%. The average change rate for MIP was 68% and 57% for MEP. The Wilcoxon signed-rank test was performed, achieving a statistically significant difference (z=-2.807, p=0.005). Conclusion: Applying the MET on the quadratus lumborum muscle improves its performance and increases respiratory muscle strength.
Correlation Between Protein, Calcium and Zinc Intake with Stunting in Children Age 3-5 Years Old in Gubeng, Mojo, Surabaya

Stunting is a condition that occurs as the result of the disruption in the growth of height due to poor nutrition intake and nutrition status, repeated incidence of infection and inadequate psychosocial stimulation. In year 2017, the prevalence status for stunting incindence in Indonesia is categorized as high, reaching at 29,6%. This study was conducted to determine the correlation between nutritional intake of protein, calcium and zinc with the incidence of stunting. This study was an observational analytic research with a case control method, conducted to determine the correlation between exposure of risk factors and disease by comparing stunting groups with non-stunting groups. This study obtained a relation between depleted calcium intake and stunting incidence using the Fisher’s Exact test with a p value of 0.001 and odd ratio 0.056. A significant correlation of insufficient calcium intake with the incidence of stunting was found, yet there were no correlation between insufficient protein and zinc intake with the incidence of stunting. Keywords: stunting; protein; calcium; zinc
A study of utilization pattern of psychiatric emergency services (PES) in Al-Qassim Region, Saudi Arabia

Objective: The psychiatric emergency services (PES) are essentially one of the most important components of all mental health delivery systems. The goal of this research is to focus on the utilization pattern and clinical profiles of clients requiring these services. Methods: A 9-year relevant sociodemographic and clinical data from January 1985 to December 1993 of patients (n=3570) recorded in well maintained registers in Buraidah Mental Health Hospital, Kingdom of Saudi Arabia, were extensively reviewed in a retrospective fashion. Results: The analysis of the data revealed the underutilization of PES by females (n=1149, 30.6%) in all age groups. The functional psychoses (n=1400, 37.3%) followed by drug-related diagnoses (n=403, 11.29%) were the most frequent problems among patients, admitted mainly involuntarily via these PES. Contrastingly patients voluntarily seeking PES were having diverse neurotic disorders (n=1172, 32.83%), in fact the majority of them were not in real need of PES. Conclusions: It was concluded that the PES were appropriately used by patients (50%) with different forms of psychoses but at the same time relatively misutilized by clients (40%) with neurotic disorders. The latter perspective, therefore, underscores the tremendous significance of mental health educational programs directed towards the appropriate uses of PES. The other important implications of this research are: (1) there is a further need to study prospectively the psychiatric emergencies and (2) there is a need to expand the psychiatric emergency services in the Kingdom of Saudi Arabia which at least should include mobile crisis intervention units, telephone consultations and crisis hospitalization in psychiatric emergency services.
Microphysical Effects of Water Content and Temperature on the Triboelectrification of Volcanic Ash on Long Time Scales

The effects of water and temperature on the triboelectrification of granular materials have been reported by numerous authors, but have not been studied robustly in the context of volcanic plumes. Here, we present the results of a set of experiments designed to elucidate how environmental conditions modulate the triboelectric characteristics of volcanic ash in the upper region of the convective column. We find that small amounts of water can reduce the charge collected by submillimeter‐sized ash grains by up to an order of magnitude. Increasing temperature at a constant relative humidity also appears to decrease the amount of charge gained by particles. Analysis of our data shows that if particles undergo low‐energy, low‐frequency collisions in humid environments under minute‐long time scales, charge dissipation dominates over charge accumulation. Thus, our work suggests that triboelectric charging may be an inefficient electrification mechanism outside of the gas‐thrust region where collision energies and rates are high and residence times are low.
Thermal Behavior of Aerogel-Embedded Nonwovens in Cross Airflow

Abstract Thermal performance of aerogel-embedded polyester/polyethylene nonwoven fabrics in cross airflow was experimentally studied by using a laboratory-built dynamic heat transfer measuring device in which the fabric could be applied on a heating rod. Experiments were performed with different airflow velocities and heating conditions. The temperature–time histories of different materials were collected and compared. The temperature difference and convective heat transfer coefficient under continuous heating were analyzed and discussed. Results showed that under preheated conditions, the aerogel-embedded nonwoven fabrics had very small decrease in temperature and good ability to prevent against heat loss in cross flow. As for the continuous heating conditions, the heat transfer rate of each material showed an increasing trend with increase in the Reynolds number. The aerogel-treated nonwoven fabric with the least fabric thickness and aerogel content delivered a significantly increased heat transfer rate at higher Reynolds number. Thicker fabrics with higher aerogel content could provide better insulation ability in cross flow.
Mechanism of upstream promoter element stimulation of transcription at a ribosomal RNA promoter determined by single-molecule imaging

DNA elements upstream of transcription promoters play a role in regulating transcription initiation in all organisms. In bacteria, upstream A-T rich sequences called UP elements can stimulate transcription through contact with the α subunit C-terminal domain (αCTD) of core RNA polymerase (RNAP), but the kinetic mechanisms by which they do so remain unclear. We investigated the role of the UP element in stimulating initiation from the strong E. coli 16s rRNA promoter using single-molecule fluorescence microscopy to visualize σ70RNAP holoenzyme binding and the formation nascent RNA by oligonucleotide probe hybridization on individual DNA molecules containing the rrnB P1 promoter. By directly detecting initial binding of σ70RNAP to promoter and monitoring the lifetimes of promoter-polymerase complexes, the experiments reveal the kinetic mechanism of polymerase recruitment to the promoter and the subsequent conformational change that stabilizes binding. The presence of UP stimulated the rate of initial binding of polymerase to promoter by at least six-fold, and this stimulation was fully sufficient to account for the increase in initiation rate by UP. Thus, UP likely functions at this strong promoter simply by acting as a binding target for the rapidly reorienting αCTD domain tethered to the core polymerase. In contrast, there were only minor effects of UP on the measured rates of the conformational change or the dissociation rates of the initial σ70RNAP promoter complexes. These studies define a paradigmatic kinetic mechanism for stimulation of transcription initiation by direct αCTD-DNA interactions. This mechanism can serve as a building block of more complex regulatory architectures in which αCTD promotes transcription through interactions with both DNA and protein activators.
The context and process of pediatric HIV disclosure

ABSTRACT This qualitative study sought to elicit the context and process of disclosure to children living with HIV (CLHIV) on antiretroviral treatment in Nigeria. The study, nested in a larger study, involved detailed interviews with 15 parent/caregivers of children ≥6 years, who had been told they were living with HIV. Most children were disclosed to at home by their parents/caregivers. The common reason for disclosure was related to the children taking their drugs. Disclosure was mostly unplanned and a one-off event, even when it was the healthcare worker who disclosed. The conversation about the child’s HIV status took place in private between the child and parent(s)/caregiver. Where several children were living with HIV in the family, parents/caregivers would usually disclose to the children at the same time, rather than individually. Children’s reaction to disclosure ranged from no reaction to shock and crying. Some parents felt they did not have the right skills to disclose. The disclosure decision model provides some insight into the disclosure process.
Eradicating Income Inequality in Lower Middle-Income Countries

Studying the distribution of income is an important issue to know what factors which affect to make income distribution more equitable, what factors can be the key to resolving the problem of income inequality, and shortening the distance between the poor and the rich. This paper studies the relationship between human capital, inflation rate, unemployment rate, physical capital, fiscal expenditure, gross domestic product growth, and urbanization on income inequality in 52 Lower Middle-Income Countries throughout 1990-2014. The authors estimate the impact of seven independent variables on income inequality as a dependent using Prais-Winsten with the robust model over period 1990-2014 at 52 Lower Middle-Income Countries. The results indicate an increase in human capital (gross school enrollment tertiary) can make the income distribution more even in the long run. The writers conclude that increases in human capital can reduce Gini coefficient and hence make income distribution fairer.
Screening for Methicillin-Resistant Staphylococcus aureus: Reliability and Accuracy

To the Editor—We read with great interest the article by Lucet and Regnier in Clinical Infectious Diseases that discussed the controversy regarding screening and decolonization for methicillin-resistant Staphylococcus aureus (MRSA). Whether screening effectively detects a significant proportion of patients colonized with MRSA and whether decolonization is effective for the prevention of infection are matters of debate. We would like to briefly report a study conducted in a 706bed tertiary care hospital, the results of which may add to the current data that exist on screening for MRSA. In our institution, screening for MRSA is performed by culturing samples obtained from the anterior nares alone. Although some have found swab samples of the nares to be of sufficient utility, others assert that cultures of samples obtained from a combination of sites are necessary for adequate levels of detection. To assess the effectiveness of the nares swab as a screening tool, we conducted a retrospective analysis of cultures of nares specimens at our institution and compared the rates of concordance and discordance with the results of concomitantly performed clinical cultures. We searched our Web-based infection prevention database for all nares swab samples tested for patients hospitalized at our institution during the calendar year 2008. Another query was performed to detect all clinical cultures with positive results for MRSA during the same time period. A clinical culture was defined as any culture not originating from a screening test of nares samples. We paired the 2 data sets and proceeded to exclude all patients for whom only nares screening tests or only clinical cultures were performed. Of the remaining data, we included only those patients for whom samples were obtained for both a nares screen and a clinical culture within 48 hours. Concordance was defined as the presence of both a nares screen and a clinical culture result positive for MRSA within 48 hours. Similarly, discordance was defined as a negative nares screen result but a positive clinical culture result for MRSA within 48 hours. A total of 630 events met the inclusion criteria for analysis. Of these, only 206 (32.7%) fulfilled the definition of concordance, whereas 114 (18.1%) fulfilled the definition of discordance. Of 320 clinical cultures with positive results for MRSA, only 206 of the matching nares screen culture results were also positive for MRSA. This yielded a sensitivity of 64.4% for the nares screen. The specificity, negative predictive value, and positive predictive value TABLE i. Concordance and Discordance between Cultures of Nares Samples and Clinical Cultures for Methicillin-Resistant Staphylococcus aureus
Broadband vibration damping of non-periodic plates by piezoelectric coupling to their electrical analogues

Several solutions for multimodal vibration damping of thin mechanical structures based on piezoelectric coupling have been developed over the years. Among them, piezoelectric network damping consists in using piezoelectric transducers to couple a structure to an electrical network, where the transferred electrical energy can be dissipated. In particular, the effectiveness of coupling rods, beams and plates to their analogous electrical networks has been proven. This work is the first step going towards more complex structures. After defining and experimentally validating a fully passive electrical analogous network of a simply-supported plate, the study is extended to the damping of a non-periodic plate. The non-periodicities here studied include the addition of a local mass and a variable thickness. Numerical simulations and experiments show that in these cases, a broadband damping is achieved once the piezoelectric transducers are coupled to an adequate analogous network. A finite element model of the structure coupled to a 2D non-periodic electrical network is concurrently developed and validated, which is another contribution of the present work.
The Influence of Vocabulary Mastery, Reading Interest, and Learning Motivation toward Translation Skill

The purpose of this study is to know whether or not there is a positive and significant influence of vocabulary mastery, reading interest and learning motivation toward translation skill. This study applied a quantitative approach. The population of this study was 285 while the sample was 175 students which taken by cluster random sampling. The techniques for collecting data were test and questionnaire. The collected data were analyzed by using SPSS version 21.0. The result of the research shows that vocabulary mastery, reading interest and learning motivation have a positive and significant influence toward translation skill.
PENGEMBANGAN MODEL LATIHAN FLEKSIBILITAS TINGKAT LANJUT DALAM PEMBELAJARAN PENCAK SILAT

Penelitian ini bertujuan untuk mengembangkan model latihan fleksibilitas tingkat lanjut dalam pembelajaran pencak silat.Jenis penelitian ini adalah penelitian pengembangan. Prosedur pengembangan bahan ajar menggunakan model Borg ang Gall meliputi 10 tahap yaitu: (1) penelitian dan pengumpulan informasi, (2) perencanaan, (3) Mengembangkan bentuk pendahuluan produk, (4) uji lapangan persiapan, dan (5) revisi produk utama, (6) uji lapangan utama, (7) pelaksanaan revisi produk, (8) uji lapangan oprasional, (9) revisi produk akhir, (10) penyebaran dan pengimplementasian. Instrumen pengumpulan data yang digunakan adalah kuisioner.Teknik analisis data yang digunakan yaitu deskriptif kualitatif dan kuantitatif.Hasil penelitian menunjukkan bahwa validasi bahan ajar ditinjau dari aspek isi adalah sangat baik dengan persentase 100%. Ahli mata pelajaran dengan persentasi 100%. Validitas menurut para siswa terhadap model latihan fleksibilitas tingkat lanjut dalam pembelajaran pencak silat yang dikembangkan adalah (1). uji lapangan persiapan, (2) uji lapangan utama, (3) dan uji lapangan oprasional memperoleh presentase masing-masing sebesar 96,7%, 98,6% dan 98,7% dengan kualifikasi sangat baik dan tidak ada revisi. Berdasarkan hasil penelitian disimpulkan model latihan fleksibilitas tingkat lanjut dalam pembelajaran pencak silat layak digunakan menurut uji ahli, uji coba lapangan persiapan, uji lapangan utama dan uji coba operasional.Penelitian ini diharapkan dapat dieksperimenkan untuk mengetahui keefektifannya dalam meningkatkan hasil belajar dan prestasi.