Miracle-dz/UniFAR-FTUs huggingface dataset:
The chemical composition of the essential oil of leaf celery (Apium graveolens L. var. Secalinum Alef.) under the plants' irrigation and harvesting method.

Qualitative and quantitative composition of the ess ential oil is subject to different types of variability. The aim of this study was to determine the effect o f irrigation and harvest date on the content and composition of esse ntial oil distilled from leaves, petioles and leaf blades of Apium graveolens L. var. secalinum Alef. Drip irrigation was carried out twice in the third 10 days of July and twice in the third 10 days of August. A single dose of water was 20 mm. The raw material was harve sted on September 7 and October 17, thus collecting leaves after 120 and 161 days o f plant growth, respectively. Irrigation increased the concentration of volatile substances in leaf blades (0.68%) and decreased the content of these components in petioles (0.24%) . Celery leaves harvested in October contained significantly less essential oil (0.34%) compared to those collected in the first 10 days of September (0.53%). Monoterpenes proved t o be the main fraction in the essential oil of leaf celery, limonene and myrcene being predominant among them. Most limonene (75.77%) was found in petioles of irrigated pl ants. Leaves of irrigated plants contained more limonene and less myrcene compared to l eaves of non-irrigated plants. More myrcene and less limonene were determined in leaves harvested in September than in those harvested in October.
Molecular phylogeny of Anatolian and Cypriot donkey populations based on mitochondrial DNA and Y-chromosomal STRs

Evciltme bolgeleri ve modern evcil esek populasyonuna katkida bulunan soylar, Nubian yaban esegi haric, hala bilinmemektedir. Bu calisma Anadolu eseginin evciltmesi hakkindaki bosluklarin doldurulmasi icin tasarlanmistir. Turkiye’den 68 Anadolu esegi ve Kibris’tan yedi esek, D-loop ve cytochrome b gen bolgeleri acisindan analiz edilmistir. Incelenen orneklerden 30 erkek ayni zamanda ata ait Eca.YM2, Eca.YP9 ve Eca.YE1 isimli uc adet Y-kromozomal kisa ardisik tekrar dizileri (STRlar) ile genotiplendirilmistir. Anadolu esek populasyonu D-loop sekanslarindan elde edilen haplotip ve nukleotid cesitliligi (h=0.756±0.0500 ve π=0.1688±0.0012) orta duzeyde yuksek bulunmusken, Kibris esek populasyonunda buyuk olcude dusuk (h=0.524±0.209 ve π=0.00176 ± 0.001) bulunmustur. Anadolu eseklerinin %35’i Clade 1’de Nubian yaban esegi ile kumelenmisken, kalan %65’i ve Kibris eseklerinin %100’u Clade 2 olarak kumelenmistir. Sunulan calismada Clade 2 Somali soyundan ve Asya yaban eseklerinden genetik olarak farkli cikmistir. Boylece bu soylarin Anadolu ve Kibris eseginin atasi olamayacaklari belirlenmistir. D-loop ve sitokrom bolgeleri icin, sirasiyla, 15 ve 6 haplotip ayrimini saglayan 17 ve 4 nukleotid degisimi belirlenmistir. Analiz edilen Ykromozomal STR’lar monomorfik bulunmustur. Eca.YM2, Eca.YP9 ve Eca.YE1 icin sirasiyla 109, 190 ve 195 allel buyuklukleri belirlenmistir
Food niche segregation between sympatric golden jackals and red foxes in central Bulgaria

In Europe, the range of the golden jackal (Canis aureus) has expanded since the mid-twentieth century, but little is known about how it interacts with other sympatric carnivores. Among European countries, Bulgaria has the largest population of golden jackals and jackal numbers have increased around two-fold during the past two decades, particularly in lowland habitats. Larger canids often competitively exclude, or even kill, smaller sympatric ones, especially when guild dynamics are in flux due to population re-establishment. We therefore investigate whether trophic niche segregation occurs between golden jackals and red foxes (Vulpes vulpes) in central Bulgaria, where both species are sympatric. Because jackals are more abundant in lowland than in upland Bulgaria, we further investigate whether habitat elevation affects the strength of trophic competition. From the analysis of stomach contents of both species, collected from lowland and upland areas during hunting seasons between 1997 and 2009, we found no significant food niche overlap, and no effect of elevation on trophic interactions. In lowland habitat, golden jackals mainly scavenged carcasses of domestic animals, whereas in upland habitat they consumed mostly carcasses of wild ungulates. In contrast, red foxes predominantly and consistently predated rodents in both habitats. This suggests that trophic segregation facilitates the coexistence of these canids under these prevailing population conditions. Nevertheless, we stress that as golden jackals colonize Eastern Europe, impacts on red foxes, and consequences for ecological communities, should be monitored carefully, especially in regions with less carrion available to support jackals.
Nuclear Medicine Imaging in Rheumatic Diseases

The rapid development of medical imaging technologies has greatly enhanced the utility of nuclear medicine imaging modalities over the last decade. Hybrid imaging technology merging computed tomography (CT) with single-photon emission computed tomography (SPECT) or positron emission tomography (PET) allows superimposing the physiologic data obtained by SPECT or PET on the detailed anatomy of CT, yielding a better understanding of the disease status and improving diagnostic performance. However, the conventional whole body bone scan and three phase bone scan still have their own distinct role as diagnostic imaging, reflecting the changes of bone metabolism in benign and malignant diseases, including rheumatic diseases. A review of each nuclear medicine imaging technique and clinical applications in various conditions of rheumatic diseases will be presented in this article. (J Rheum Dis 2017;24:4-13)
A survey of the Odonate (dragonfly) fauna of western India with special remarks on the genera Macromia and Idionyx and descriptions of thirty new species

Although S0111e of the earliest types of dragonflies came from Western India, no area of the Continent has been so little worked in respect to this order of insects. Up to less than a decade ago, no dragonflies had been reported from the area since 1842, when Ralnbur described several species which must clearly have been collected in Bombay, Poona and the Nilgiris. Such are,-Ictinus rapax, Vestalis gracilis, Pseudagrion microcephalum and P. deco1'um from Bombay, Micromeruslineatus, Copera marginipes 1 and Ohloroneura quadrimaculata from Poona, Pseudophcea dispar and Indoneura gomphoides froln the Nilgiris. Selys described Rhinocypha bisignata and PhylloneUt1'a westerrnanni from the Nilgiris in 1853 and 1860, respectively. Some idea of how little the area has been ,vorked may be gained by taking Coorg as an example of the whole. Only a s~ngle dragonfly has been reported fronl this district although during the past year I have been able to list over 120' species. Fronl the whole of Malabar hardly a single species has been reported and the sanle is alnl0st equally true of the whole of Kanara, Cochin and Tra vancore.
Camarões de Profundidade coletados no norte do Brasil (Crustacea: Penaeidea e Caridea).

A realizacao de prospeccoes entre as isobatas de 300 e 600 metros, na Regiao Norte brasileira, entre os Estados do Amapa e Maranhao, a partir da implantacao do Programa “REVIZEE”, propiciou a obtencao de um excelente acervo zoologico. Entre estes, ressaltam-se os crustaceos, representados, primordialmente, pelos Penaeidea e Caridea. As coletas foram realizadas durante o segundo semestre de 1996 e primeiro de 1997 e 1998, a bordo do Navio de Pesquisa “Almirante Paulo Moreira”, sob a responsabilidade do Centro de Pesquisa e Extensao Pesqueira do Norte do Brasil (CEPNOR/IBAMA–MMA), utilizando-se redes de arrasto de fundo, objetivando-se, alem do conhecimento da fauna da Zona Economica Exclusiva do Brasil (ZEE), verificar a ocorrencia, em aguas de maior profundidade, de especies potencialmente economicas. Foram identificadas 14 especies, distribuidas em 11 generos e 7 familias. Quanto a profundidade, a faixa compreendida entre as isobatas de 300 e 400m foi a mais rica em numero de especies. Por outro lado, na faixa entre 400 e 600m foram coletadas as especies consideradas como de maior importância potencial, merecendo um estudo mais acurado Aristeus antillensis A. Milne Edwards & Bouvier, 1909 e Aristaeopsis edwardsiana (Johnson, 1867). Para Heterocarpus ensifer A. Milne Edwards,1881, que ocorreu entre 300 e 400m, tambem sao validas estas recomendacoes. Palavras-chave: Camaroes de aguas profundas; Crustacea Decapoda, Programa REVIZEE.
Investigating cancer aetiology through the analysis of somatic mutation signatures

Cellular genomes accumulate alterations following exposures to exogenous factors, like environmental agents such as tobacco smoking or UV, or to endogenous mechanisms such as DNA replication errors. Analysing the causes and consequences of these changes allows a better understanding of the mechanisms underlying cancer development and progression. Next-generation sequencing (NGS) technologies provide the opportunity tostudy the nature of the resulting alterations on a genome-wide scale and started to reveal distinct mutational signatures specific to past carcinogenic exposures providing clues on cancer aetiology.The aim of my thesis was to develop user-friendly bioinformatic tools and methods for facilitating the analysis and interpretation of carcinogen-specific mutational signatures from NGS data. Applying these tools and methods to human tumours and experimental models of mutagenesis led to a better characterisation the mutational signature of aristolochic acid (AA), as well as other carcinogens of interest
Comparison of high sensitive and conventional troponin assays in diagnosis of acute myocardial infarction

Abstract Introduction We aimed to compare the positive predictive values (PPV) and negative predictive values (NPV) of four cardiac troponin assays in the diagnosis of AMI in Turkish population. Methods This study is an observational comparative study, which is performed between 2012 and 2013 (527 patients). Troponin levels were measured with chemiluminescence Cobas troponin T assay, immunofluorescence Triage troponin I assay and immunochromatographic Toyo troponin I assay. Results Sensitivity and specificity of immunofluorometric assay (Radiometer) are 56.82% and 71.34%; immunochromatographic assay (Toyo) are 29.4% and 88.62%, immunofluorescence assay (Triage) are 47.13% and 76.12%, chemiluminescence assay (Roche) are 60.49 and 67.42%, respectively. PPV, NPV and positive likelihood ratios (LR+) of immunofluorometric assay (Radiometer) are 45.5%, 79.7% and 1.98, immunochromatographic assay (Toyo) are 51.5%, 75.4% and 2.58, immunofluorescence assay (Triage) are 46.5%, 76.6% and 1.97, chemiluminescence assay (Roche) are 45.8%, 78.9% and 1.86, respectively. In four assays, troponin levels were statistically significant higher in AMI positive group in comparison to negative group (p<0.001 for all). Conclusion There was no statistically significant difference between these troponin methods in comparisons of PPV and NPV in the diagnosis of AMI, but low sensitivity of Triage and Toyo assays should be considered.
Is it possible to keep the exoskeleton of the crab Callinectes ornatus soft for several days?

Soft-shell crab is considered a gastronomic delicacy, reaching high values in the international market. The process of hardening of the crab’s exoskeleton after moulting takes approximately two days to complete; however, the duration for which the shell remains at the consistency of high commercial value is only 3 hours on average. After this period, the shell assumes a consistency classified as “paper”, later becoming “hard” again. The goal of this work was to evaluate the use of the crabs themselves to alter the chemical characteristics of the water and thereby increase the amount of time during which they can be marketed as “soft-shell crab”. In this work, 241 individuals of Callinectes ornatus were used in two experiments. In the first experiment, the animals were maintained in a collective system with filtration and partial daily water renewal. In the second experiment, the crabs were maintained in a collective system with filtration but no water renewal. In Experiment 1, the chemical characteristics of the water remained unchanged over time (p > 0.05), and the median time to hardening of the exoskeleton to the paper consistency after moulting was 3 hours. Over the course of Experiment 2, there was a significant reduction (p < 0.05) in pH and significant increases in the ammonia and nitrite concentrations. When moulting occurred in water with a pH below 7.3 and total ammonia concentrations above 6.0 mg/L, the crabs’ shells did not harden, and it was possible to keep them soft for up to 5 days.
Biological Profiling of Drugs for Treatment of In‐stent Restenosis

To elucidate the actions of drugs that are useful in treating in‐stent restenosis, we compared the activities of both Paclitaxel and Sirolimus against dexamethasone, actinomycin D, or 17β‐estradiol in a panel of human cell‐based assays that model biological processes involved in restenosis. Paclitaxel and Sirolimus each inhibited endothelial cell (EC) and vascular smooth muscle cell (VSMC) growth, while dexamethasone promoted VSMC proliferation. Sirolimus and actinomycin D each decreased tissue remodeling markers in ECs and fibroblasts. Paclitaxel had no remarkable effects, while dexamethasone enhanced PAI‐1 expression. Paclitaxel did not affect T cell activation or peripheral blood mononuclear cell (PBMC)/T cell CD40/CD40 ligand and MCP‐1 expression. Sirolimus, 17β‐estradiol, dexamethasone, and actinomycin D each inhibited one or more of these inflammatory markers. In VSMC cultures, Paclitaxel up‐regulated thrombomodulin and decreased tissue factor expression. In contrast, Sirolimus increased tissue factor expression, but had no effect on thrombomodulin in cultures containing ECs and PBMCs. Dexamethasone, 17β‐estradiol, and actinomycin D each had little or no effect on these thrombosis factors. These results suggest that drugs considered for future use in DES platforms should inhibit VSMC proliferation to afford clinical efficacy with in‐stent restenosis. Further optimization would include drug actions that are not directed at ECs so as to permit proper vascular healing following DES deployment.
Comparison of Direct Immunofluorescence (DIF) Method and Giemsa Staining with PCR Method for Detection of Chlamydia trachomatis in Patients with Follicular Conjunctivitis

Background: Chlamydia trachomatis is the most common cause of chronic follicular conjunctivitis. As a rapid diagnosis is important in the reducing the long-term squeal of the diseases, the objective of this study was to compare the three methods, direct immunofluorescence (DIF), staining and PCR, for detection of Chlamydia trachomatis in patients with follicular conjunctivitis. Material and methods: Overall 90 patients with conjunctival were enrolled in this study smears were prepared for DIF and Giemsa staining. PCR amplification after Extraction performed using CT1 and CT5 primers designed from Omp1 gene. Results: Of the 90 patients, 28 (31.1%) were positive by DIF and 13 (14.4%) by Giemsa staining; and 35 patients (38.8%) showed positive results in PCR. Sensitivity, specificity, predictive positive value, and negative predictive value of DIF in comparison to PCR respectively were calculated as 88.33, 100, 100 and 88.70. Sensitivity, specificity, predictive positive value and negative predictive value of DIF in comparison to PCR respectively were calculated as 61.40, 100, 100 and 71.42. Therefore, sensitivity and negative predictive value of DIF are significantly higher than Giemsa staining. Conclusion: DIF is more sensitive and more reliable than Giemsa staining for detection of Chlamydia trachomatis in the conjunctiva samples of patients with follicular conjunctivitis.
Functional Expression of TRPV4 in the Mouse Colon

The Transient Receptor Potential (TRP) family of non‐selective cation channels allow cells to sense diverse physical and chemical stimuli, and also mediate or amplify the actions of many GPCRs. TRPs participate in many physiological and pathophysiological processes and are an emerging therapeutic target for pain and neurogenic inflammation. TRP vanilloid 4 (TRPV4) is activated by stimuli commonly present in the colon, including mechanical stimulation, lipid mediators and GPCR‐dependent signaling cascades. TRPV4 is upregulated in inflammatory bowel disease and may have a proinflammatory role in experimental colitis via a neurogenic mechanism. Although TRPV4 has important roles in colonic function, very little is known about where TRPV4 is expressed in the gut. This study examines novel non‐neuronal sites of TRPV4 expression in the colon and inflammation‐associated changes in TRPV4 signaling.
Düzce ve Çevresinde Gıda Olarak Tüketilen Yabani Bitkilerin Tüketim Biçimleri ve Besin Öğesi Değerleri

Bu calismada Duzce ve cevresinde yayilis gosteren yabani gida bitkilerinin yerel halk tarafindan tuketim bicimleri ve bu bitkilerin gida icerikleri arastirilmistir.Duzce ve cevresinde, Falcaria vulgaris (Kazayagi), Tussilago farfara (Kabalak), Trachystemon orientalis (Kaldirik), Capsella bursa-pastoris (Cobancantasi), Raphanus raphanistrum (Yabani turp), Chenopodium album subsp. album var. album (Sirken), Vaccinium myrtillus (Cali cilegi), Mentha longifolia subsp. typhoides var. typhoides (Yabani Nane), Thymus praecox subsp. skorpilii var. skorpilii (Kekik), Malva neglecta (Ebegumeci), Portulaca oleracea subsp. oleracea (Semizotu), Urtica dioica (Isirgan) olmak uzere 10 familyaya ait 12 bitki taksonu belirlenmistir. Su miktari en yuksek Kaldirikte (% 84,9), en dusuk Yabani turpta (% 44) belirlenmistir. Organik madde miktari en yuksek Cali cileginde (% 94) belirlenirken en dusuk Semizotunda (% 76) tespit edilmistir. Protein miktari en yuksek Yabani turpun yapraginda (% 32,26), en dusuk Semizotunda (% 1,59) belirlenmistir. Yag miktari en yuksek Kabalagin yapraginda (% 2,33), en dusuk Semizotunda (% 0,33) tespit edilmistir. Seluloz miktari en yuksek Kekikte (% 28,1), en dusuk Yabani turpun kok kisminda (% 8,35) belirlenmistir. Tanen iceriginin en yuksek Isirganda (229,9 g. kg-1 KA), en dusuk Yabani turpun kok kisminda (5,2 g. kg-1 KA) oldugu saptanmistir. Antioksidan kapasite en yuksek Kabalagin yaprak sapinda (4,734 mmol TR g-1), en dusuk Yabani turpun kok kisminda (1,004 mmol TR g-1) tespit edilmistir. Arastirilan tum bitkilerde, en yuksek mineral madde icerigi K, en dusuk Cu minerali olarak belirlenmistir.
Effects of cadmium on metallothionein and histology in gills of tilapia (Oreochromis niloticus) at different salinities

ABSTRACT The objectives of this study were to evaluate the effects of sublethal cadmium concentrations on the levels of cadmium, metallothionein (MT) and histological changes in gills of East Java strain tilapia (Oreochromis niloticus) at different salinity levels. The levels of cadmium in control gills were not significantly different at 0, 5 and 10 practical salinity unit (PSU). The cadmium concentrations in gills of cadmium-exposed fish were significantly higher at 0 PSU than at 5, 10 and 15 PSU. The MT concentrations in control gills were not significantly different at 0, 5, and 10 PSU. The MT concentrations of cadmium-exposed fish were significantly higher than those in respective control groups at 0, 5 and 10 PSU. Significant gill damage occurred in fish exposed to cadmium at lower salinity. The epithelial lifting was noted at gills of fish exposed to 2.5 mg/L of cadmium at 0 PSU, and telangiectasis was observed at gills exposed to 5 mg/L of cadmium at 0 PSU. The level of gill damage decreased with increasing salinity of media. The increased MT and histological changes in gills of our findings could be a protective response of animals to toxic effect of cadmium.
Electro-diffusion modulation of synaptic input in dendritic spines using deconvolved voltage sensor time series

The inward current flowing inside the post-synaptic terminal of a neuron modulates transiently the membrane voltage potential. Most of the excitatory connections are made on dendritic spines characterized by a large variability in their geometry.How the voltage in a spine is modulated by geometry remains elusive due in part to the absence of direct measurements. To understand the spine voltage-current relation, we develop here a model for the voltage and we use it to extract electrical properties from live cell imaging data. We first deconvolve the genetically encoded voltage sensor expressed in hippocampal neurons and then use electro-diffusion theory, to compute the electric field and the ionic flows induced in a dendritic spine.The ionic flow is driven by the electric field coupled to the charge densities that interact through the non-cylindrical spine geometry. We determine the I-V relation and conclude that the spine effective resistance is mostly determined by the neck geometry. This modulation of synaptic inputs by the spine neck is significantly larger than what was expected from traditional cable models. Thus modulating the postsynaptic current can be achieved by changing the number of receptors or by altering the spine geometry which independently affects the transformation of current into voltage. Significance statement Dendritic spines are geometrical structures receiving most of the excitatory transmission, yet how they modulate voltage from the synaptic current is not clear due to their submicron small size and specific non-cylindrical geometry. We study here the conversion of the synaptic current into voltage modulated by the spine geometry. Our approach is based on the electro-diffusion theory and we show that the spine neck is the main resistance filter, while the voltage is maintained constant in the head. Finally, we extract the effective resistance using a deconvolution of the genetically encoded voltage indicators expressed in hippocampal neurons. The present approach allows studying the electrical properties of many other structures such as glial small protrusions, cilia, and many others.
Some Physico-Chemical Characteristics in Fruits of Rose Hip (Rosa spp.) Genotypes from Bolu Province in Western Part of Turkey

More recently, functional foods or food supplements which can protect humans from oxidative stress and several diseases have attracted worldwide interest. Among functional foods, fruits were given special attention, particularly wild edible fruits (neglected or underutilized fruits). There are various neglected and underutilized fruit tree species grown in Turkey solely. They could be exploited directly as foods, or used to obtain valuable natural compounds and derivatives. Rose hip (Rosa spp.) is one of them. The aim of the study is to determine some fruit characteristics of promising rose hip selections from Bolu province in the western part of Turkey. In the selection study, around 100 wild growing rose hip plants were investigated and among them 9 promising genotypes were selected based on rose hip selection criteria. The fruit mass, fruit flesh ratio, soluble solid content, titratable acidity, total dry matter and vitamin C content of these selected nine genotypes ranged from 1.40-2.77 g, 64.92-82.83%, 24.10-30.50%, 0.04-1.55%, 32.44-56.94% and 332.42-1603.52 mg/100 g respectively. Among the 9 promising genotypes, two genotypes had high, two genotypes had medium and five genotypes had low level of thorn.