Miracle-dz/UniFAR-FTUs huggingface dataset:
The Correlation of Plasma 25-Hydroxyvitamin D with Risk of Colorectal Cancers in Asian Population

: Recently, it has been found that vitamin D deficiency links to highly prevalent chronic illnesses, such as cardiovascular disease, diabetes mellitus and cancer. Colorectal cancer is the third most prevalent cancer and the fourth most common cause of cancer mortality worldwide with increasing incidence in Asian countries. Western-based population studies has stated that there is an inverse relationship between plasma 25(OH)D and risk of colorectal cancer. Despite the increase on colorectal cancer incidence and low vitamin D status in Asian countries due to lifestyle change, very few Asian-population based studies on vitamin D and colorectal cancer have been conducted. We have aimed to evaluate articles that assessed the correlation of plasma 25(OH)D with risk of colorectal cancers in Asian population. The search for studies was conducted using Medline via Pubmed. Overall, 646 potential articles were identified, and after screening, 2 articles met eligible criteria for inclusion. Evidence suggest that plasma 25(OH)D levels may have inverse relationship with colorectal cancer, but specifically rectal cancer, rather than colon cancer in both women and men. There is still a very high need in the future for high-quality studies that assess the correlation of plasma 25(OH)D to the risk of colorectal cancer in Asian population.
The Synectics Teaching Method: Effects on the Problem- Solving and Creative Thinking Skills of Learners in Physics

: The study focused on the effects of the synetics teaching method on the student’s creative thinking and problem-solving skills in physics. The researcher used the quantitative research method, specifically the descriptive quasi- experimental design was employed to find out if the use of the synectics teaching method enhances the problem-solving and creative thinking skills of the Grade 12 students in physics. Intact groups were selected and then matched according to age, final grade in Physics 1, pre-test in problem-solving skills and pre-test in creative thinking skills. The post-test mean scores of the experimental and control groups are 17.52 and 14.90 respectively. The two groups in creative thinking skills slightly differed with 3.978 for experimental group and 3.61 for the control indicating an improved in creative thinking skills of the students. The difference in the pre-tests and post-tests scores of the two groups in the problem-solving skills test of the experimental group showed better improvement when synectics teaching techniques in the eight (8) modules were utilized. The p-value of 0.00243 indicates that the post test mean scores of the two groups differ significantly. The experimental group performs better than the control group in terms of Problem-Solving Skills. Finally, the relationship between problem solving skills and creative thinking skills of the experimental group revealed that the interaction between the creative thinking skills vis-à-vis problem-solving skills has low significant relationship as implied by the p-value of -0.045 indicating that the high problem-solving skills of the students varies inversely with the creative thinking skills.
Economic and productive impact of an herbal mixture with choline derivatives on rabbit production

: The use, as well as the productive and economic effect of herbal compounds on rabbit production has been little studied, for this reason, the objective was to evaluate the effect of a polyherbal mixture rich in choline conjugates based on Trachyspermum ammi , Achyranthes aspera , Azadirachta indica and Citrullus colocynthis , on the economic and productive response of meat rabbits. For this, 40 New Zealand X California rabbits (30-d old) were used, which were randomized into five groups (0.0, 200, 400, 600 and 800 mg kg -1 of polyherbal DM, BioCholina ® ), the experiment lasted 34 days. The productive response, meat quality and economic indicators were evaluated. A completely randomized design with an arrangement of orthogonal polynomials was used to determine linear and quadratic effects, with a significance level of P <0.05. The results in terms of production parameters were similar between treatments, except for feed consumption ( P =0.006) and feed conversion ( P =0.005) with a linear effect at higher concentration of the polyherbal. The inclusion of the polyherbal increased pH in meat (linear, P =0.004) and coordinate b* (linear, P =0.009), it was observed that the treatment with 200 mg showed the best economic indicators, improving the income-expense ratio by 9 percentage units. It is concluded that the addition of polyherbal mixtures based on natural choline conjugate did not improve the productive variables, however, a favorable economic trend is marked with the addition of 200 mg kg -1 of DM. liver and productive function in broilers (9) , the impact on rumen fermentation in lambs (8,10) , oxidative stress and biochemical changes in dairy cows (11) , gene expression and immunostimulant effect in female calves (1) , blood analytes in lambs as indicators of lipid metabolism (12)
Gender and Disadvantage in the Evolution of Test Score Gaps Warwick-Monash Economics Student Papers

This paper details the evolution of numeracy test score gaps based on gender and socioeconomic status, particularly considering children’s early circumstances. We use the rich dataset: The Longitudinal Study of Australian Children (LSAC) to bring together two strands of literature on gaps between students on a gender and a socioeconomic basis. We establish an interrelationship between socioeconomic gaps, based on early life household income and parental education, and the gender gap in numeracy. We find that between Grades 3 to 9, boys have an advantage in numeracy scores over girls, which widens over time. By Grade 9, poorer female students are doubly disadvantaged compared to richer female students and male students. We confirm that early life circumstances continue to impact student’s achievement into adolescence, demonstrating the importance of early interventions to address gender and socioeconomic gaps. ___________________________________________________________________________ potentially influence the trajectory of student’s lives after schooling. This paper contributes to the literature on the determinants of numeracy test score gaps by including a detailed examination of the interplay between socioeconomic disadvantage and gender in influencing academic achievement. This draws together two strands of literature in this area and demonstrates that socioeconomic and gender disadvantage compound to doubly disadvantage poorer female students in their numeracy results. By measuring gender gaps in numeracy across a seven-year period between Grades 3 and 9, we are able to illustrate the evolution of gender heterogeneous effects over time, where previous papers in this area have been constrained to a shorter timespan in their analyses. We detail the differing impacts of Mother’s and Father’s education on student’s achievement, with higher Father’s education more strongly influencing students results overall, but girls being more impacted by higher Mother’s education than boys. We briefly consider the different gender impacts for indigenous and non-English speaking background (NESB) students, but this is a clear area for further research. By focusing our analysis on early household income and parental education, before children enter school, we further demonstrate the importance of early life circumstances on the evolution of socioeconomic and gender gaps throughout schooling. This has important policy implications when designing interventions to address educational inequalities. Our analysis highlights both who and when to target when designing such interventions; namely poorer female students as early as is possible.
Size Scale Effects on Linear Weir Hydraulics

iii ACKNOWLEDGMENTS . vii LIST OF TABLES . x LIST OF FIGURES . xi LIST OF SYMBOLS . xv INTRODUCTION . 1 LITERATURE REVIEW . 4 Sharp-Crested Weirs . 5 Flat-Top Crested Weirs . 10 Quarter-Round Crested Weirs . 11 Half-Round Crested Weirs . 11 Research Objectives . 15 EXPERIMENTAL FACILITIES AND SETUP . 16 Facilities . 16 Setup and Installation of Weirs . 22 TEST PROCEDURES . 23 Head-Discharge . 23 Nappe Behavior . 24 Approach Flow Uniformity . 24 RESULTS AND DISCUSSION . 26 Uncertainty . 26 Flow Regimes . 31 Vented and Non-Vented Behavior . 34 Low-Head Size Scale Effects . 50 Nappe Aeration Scale Effects . 58 Comparison to Previous Studies . 63 CONCLUSIONS . 74 ix REFERENCES . 78 APPENDICES . 80 APPENDIX A: WEIR MODEL DRAWINGS . 81 APPENDIX B: VBA CODE . 86 APPENDIX C: CURVE FIT EQUATIONS . 93
INFLUENCE OF ORGANIZATIONAL CULTURE ON ACADEMIC MOTIVATION IN A BRAZILIAN BUSINESS HIGHER EDUCATION INSTITUTION

The aim of this study is to analyze the influence of the organizational culture of a business higher education institution on student motivation. From a theoretical point of view, motivation results from the relationship between subjective factors and external conditions, such as the organization to which the student is associated. Therefore, a quantitative, descriptive and cross-sectional study was carried out with 263 students from an Iese located in southern Brazil. The results show that the most valued factors of organizational culture are cooperative professionalism and external integration. Also, organizational culture directly influences the autonomous motivation of students and acts as an external regulator, suggesting important pedagogical and managerial implications.
TADSAM:A Time-Aware Dynamic Self-Attention Model for Next Point-of-Interest Recommendation

In recent years, the next Point-of-Interest (POI) recommendation has been widely concerned with the prosperity of location-based social networks. Its purpose is to predict users’ next activities according to their current time and place. However, it mainly faces two challenges: 1) with the change of time, the historical behaviors of users show diversity and complexity, and 2) due to the sparsity of user trajectory data, it is hard to capture users’ preferences in the corresponding time pattern. Therefore, we propose a Time-Aware Dynamic Self-Attention Model TADSAM to predict the next decision-making activities of users in the future. Firstly, we use an extended self-attention mechanism to deal with the complex check-in records of the user. Secondly, considering the inﬂu-ence of time, we divide the user check-in records into different time windows and develop a personalized weight calculation method to exploit temporal patterns of the user’s behaviors. Experimental results demonstrate that our method out-performs the novel models for the next POI recommendation on sparse check-in data.
Innovation and growth of engineering SMEs in Bangalore: Why do only some innovate and only some grow faster?

This paper probes two research questions by ascertaining the factors which distinguish (i) innovative SMEs from those which are not, and (ii) SMEs which experienced a higher sales growth from those which experienced a lower sales growth, with reference to 197 engineering industry SMEs in Bangalore city. The differentiat- ing factors between innovative and non-innovative SMEs brought out that SMEs must have ‘‘own resources and capabilities’’ in the form of internal strength and deﬁnite internal strategy if they have to innovate successfully. Younger and smaller ﬁrms which are ‘‘entrepreneurial’’ in nature and which are innovative contributed to higher sales growth of SMEs compared to older and larger ﬁrms which are ‘‘salary-substitute ﬁrms’’ in nature and which are not innovative.
HOMOGENIZATION AND PHASE SEPARATION WITH MOVING WELLS-THE SUBCRITICAL CASE

Understanding the laws which govern the interfaces formed has been of vital importance to many industrial and physical applications. The ModicaMortola energy, which consists of a double well potential energy (with the wells corresponding to the preferred phases) and a gradient regularization, is the canonical idealized model for phase separation. Much of the work regarding this model occurs under isothermal conditions– the wells are always constants. It was conjectured by Gurtin [14] that this model led to a sharp interface model in the limit. This conjecture was later proved with contributions from many authors [16][18][15]. In particular, the work of Fonseca and Tartar [12] proved the conjecture under very general conditions and in the vector-valued case. However, in modern materials (such as temperature-responsive polymers), these preferred phases vary depending on the point in the material. This problem has previously been considered in the scalar case by [2][18], but those techniques cannot be adapted directly to the vectorial case. The first author with Gravina [7] has recently extended the results to the vectorvalued case under some strict conditions on the behavior of the double well potential around the wells. In the process of proving our results, we are able to also relax some of these strict conditions. In this paper, we will consider the case of phase separation within a periodically heterogeneous composite material where the scale of the interface is ε, with ε > 0, and the scale of the periodic microstructure is εα for 0 < α < 1,
Detecting Deepfakes with Multi-Metric Loss

In recent years, DeepFake techniques have advanced to generate so realistic forged content that it could jeopardize personal privacy and national security. We observe the distribution discrepancy between genuine faces and tampered faces manipulated by DeepFake techniques. It can be described that embedding vectors of genuine faces are tightly distributed in the embedding space, while tampered faces are comparatively scattered. We, therefore, propose a novel DeepFake detection method based on Multi-metric Loss. Specifically, real and fake faces are mapped onto the embedding space, which is of intra-class compactness and inter-class separation. Then by adding Weight-Center Loss to project genuine faces onto a more compact region in the embedding space, the distance between the two types of sample clusters is further expanded, thereby improving the separability of genuine and tampered samples. Moreover, the Adaptive Hardness-aware Expander is designed to further improve feature description ability of the model because the metric is always challenged with proper difficulty. Extensive experiments show that our approach can achieve state-of-the-art performance on present datasets.
Review of Paediatric Mortality in a Tertiary Hospital in Nigeria

: Introduction: Pediatric mortality is a cause for serious concern particularly in resource-poor countries all over the world. Indeed it is estimated that in 2010, about 99% of the 7.7 million death of children globally occurred in low to medium income countries (LMIC) including Nigeria. This study provides data of pediatric mortality from a tertiary hospital in Abuja the capital of Nigeria. Setting: National Hospital Abuja is a 450-bedded tertiary public hospital located in the cosmopolitan city of Abuja the capital of Nigeria. Methods: This is a retrospective analytical study involving all admissions for patient of neonatal to 15-year age extending from 1 st January 2008 to 31 st December 2017. Result: Pediatric mortality accounts for 4.9% of 14,690 pediatric admissions with a 1.3:1 male-female ratio. Most mortality (44%) occurred within the first 4 days of hospital admission and the most vulnerable age group is the neonatal age group (67%). The commonest causes of death are prematurity, neonatal jaundice and congenital malformations in neonates. Conclusion: Pediatric mortality is high in National Hospital Abuja and involves predominantly neonates.
The Effects of Alexithymia and Age on Inhibitory Control

THE EFFECTS OF ALEXITHYMIA AND AGE ON INHIBITORY CONTROL Anthony N. Correro II, M.S. Marquette University, 2020 Alexithymia is a stable personality trait typified by externally oriented thinking and difficulties identifying and describing feelings. It is associated with cognitiveaffective deficits such as poorer memory for emotional and neutral information as well as executive dysfunction. Relatedly, aging is accompanied by executive dysfunction and increasing alexithymia. Because executive functions comprise multiple cognitive skills, it is essential to demarcate which are impacted by aging and alexithymia. While age-related deficits in inhibitory control are well established, there is a dearth of literature examining inhibition in alexithymia. Thus, this study aimed to examine the effect of alexithymia on inhibition and to interrogate its potential additive impact to aging effects. Participants were 538 undergraduate students (age = 18-35) and 201 middle-aged to older adults (age = 48-92). All completed the 20-item Toronto Alexithymia Scale (TAS-20) and go, no-go, and stop-signal tasks. Following removal of participants with missing data or invalid task performance, the final sample included 384 younger and 81 older adults. Separate hierarchical regressions predicting accuracy and reaction time were examined. Post hoc models included TAS-20 subscores. Exploratory moderation and mediation models were also conducted to interrogate shared variance among covariates and predictor variables. Female sex and greater age predicted slower reaction times across all three tasks. Older age was also associated with less accurate responding to target and inhibition trials on no-go and slower and less accurate inhibition on stop. Alexithymia predicted poorer inhibition on no-go and stop via difficulty identifying feelings (DIF). Mood symptoms neither moderated nor mediated the relationship between DIF and inhibitory control. These results replicate the age-related tradeoff of speed for accuracy in reaction time and inhibition tasks. They also provide novel evidence for alexithymia deficits in non-emotive inhibitory control. The impact of DIF on both automatic (no-go) and conscious (stop) inhibitory control supports processing theories of alexithymia. In particular, DIF contributed to poorer extrinsically and intrinsically cued response suppression. Thus, top-down and bottom-up information processing may be disrupted in alexithymia. Critically, the alexithymia effects were additive to age effects extending support for alexithymia as a risk factor for cognitive aging.
CLEP_A_363429 463..473

1Department of Epidemiology, School of Public Health, Suzhou Medical College of Soochow University, Suzhou, People’s Republic of China; 2Department of Chronic Disease, Gusu Center for Disease Prevention and Control, Suzhou, People’s Republic of China; 3Department of Nephrology, The Affiliated Jiangyin Hospital of Southeast University Medical College, Jiangyin, People’s Republic of China; 4Department of Tuberculosis Control, Suzhou Center for Disease Control and Prevention, Suzhou, People’s Republic of China; 5Department of Central Office, Maternal and Child Health Bureau of Kunshan, Suzhou, People’s Republic of China; 6Department of Preventive Medicine, College of Clinical Medicine, Suzhou Vocational Health College, Suzhou, People’s Republic of China; 7Jiangsu Key Laboratory of Preventive and Translational Medicine for Geriatric Diseases, Suzhou, People’s Republic of China
Cell Division During Stress Proteostasis Network in T Cells Critical for Activation and Regulates a Major Activated as a Consequence of Lymphocyte Heat Shock Transcription Factor 1 Is

Heat shock transcription factor 1 (HSF1) is a major transcriptional regulator of the heat shock response in eukaryotic cells. HSF1 is evoked in response to a variety of cellular stressors, including elevated temperatures, oxidative stress, and other proteotoxic stressors. Previously, we demonstrated that HSF1 is activated in naive T cells at fever range temperatures (39.5˚C) and is critical for in vitro T cell proliferation at fever temperatures. In this study, we demonstrated that murine HSF1 became activated to the DNA-binding form and transactivated a large number of genes in lymphoid cells strictly as a consequence of receptor activation in the absence of apparent cellular stress. Microarray analysis comparing HSF1 +/+ and HSF1 2 / 2 gene expression in T cells activated at 37˚C revealed a diverse set of 323 genes signiﬁcantly regulated by HSF1 in nonstressed T cells. In vivo proliferation studies revealed a signiﬁcant impairment of HSF1 2 / 2 T cell expansion under conditions mimicking a robust immune response (staph-ylococcal enterotoxin B–induced T cell activation). This proliferation defect due to loss of HSF1 is observed even under nonfebrile temperatures. HSF1 2 / 2 T cells activated at fever temperatures show a dramatic reduction in cyclin E and cyclin A proteins during the cell cycle, although the transcription of these genes was modestly affected. Finally, B cell and hematopoietic stem cell proliferation from HSF1 2 / 2 mice, but not HSF1 +/+ mice, were also attenuated under stressful conditions, indicating that HSF1 is critical for the cell cycle progression of lymphoid cells activated under stressful conditions. The Journal of Immunology , 2013, 191: 4068–4079. quantiﬁed using Quanta One imaging and analysis soft- ware (Bio-Rad, Hercules, CA). The PCR products were detected using primers as follows: cyclin A2 (5 9 -CCT CTC CTC CAT GTC TGT GTT AAG-3 9 and 5 9 -GTG CTC CAT TCT CAG AAC CTG CTT-3 9 ) and GAPDH (5 9 -TGA AGG TCG GTG TGA ACG GAT TTG-3 9 and 5 9 -ACG ACA TAC TCA GCA CCA GCA TCA-3 9 ) were as described previously (37). Cyclin E1 primers (5 9 -TGC AGA TCG CAG AGC TTC TA-3 9 and 5 9 -CTT TCT TTG CTT GGG CTT TG-3 9 ) were designed using the Primer-BLAST primer designing tool.
Variability of Care and Access to Transplantation for Children with Biliary Atresia Who Need a Liver Replacement

Background & Aims: Biliary atresia (BA) is the commonest single etiology indication for liver replacement in children. As timely access to liver transplantation (LT) remains challenging for small BA children (with prolonged waiting time being associated with clinical deterioration leading to both preventable pre- and post-transplant morbidity and mortality), the care pathway of BA children in need of LT was analyzed—from diagnosis to LT—with particular attention to referral patterns, timing of referral, waiting list dynamics and need for medical assistance before LT. Methods: International multicentric retrospective study. Intent-to-transplant study analyzing BA children who had indication for LT early in life (aged < 3 years at the time of assessment), over the last 5 years (2016–2020). Clinical and laboratory data of 219 BA children were collected from 8 transplant centers (6 in Europe and 2 in USA). Results: 39 patients underwent primary transplants. Children who underwent Kasai in a specialist -but not transplant- center were older at time of referral and at transplant. At assessment for LT, the vast majority of children already were experiencing complication of cirrhosis, and the majority of children needed medical assistance (nutritional support, hospitalization, transfusion of albumin or blood) while waiting for transplantation. Severe worsening of the clinical condition led to the need for requesting a priority status (i.e., Peld Score exception or similar) for timely graft allocation for 76 children, overall (35%). Conclusions: As LT currently results in BA patient survival exceeding 95% in many expert LT centers, the paradigm for BA management optimization and survival have currently shifted to the pre-LT management. The creation of networks dedicated to the timely referral to a pediatric transplant center and possibly centralization of care should be considered, in combination with implementing all different graft type surgeries in specialist centers (including split and living donor LTs) to achieve timely LT in this vulnerable population.