Miracle-dz/UniFAR-FTUs huggingface dataset:
Effect of Camel Milk on Glucose Homeostasis in Patients with Diabetes: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

The effects of camel milk (CM) intake on glycemic control in patients with diabetes are controversial. This systematic review and meta-analysis of randomized controlled trials (RCTs) was conducted to summarize the effect of CM intake on glucose homeostasis parameters in patients with both types of diabetes mellitus; T1DM and T2DM. We searched Google Scholar, PubMed/MEDLINE, EBSCO host, CINAHL, ScienceDirect, Cochrane, ProQuest Medical, Web of Science, and Scopus databases from inception until the end of November 2021. Relevant RCTs were identified, and the effect size was reported as mean difference (MD) and standard deviation (SD). Parameters of glycosylated hemoglobin (HbA1c), fasting blood glucose (FBG), postprandial blood glucose (PBG), fasting serum insulin (FI), insulin resistance (expressed in terms of HOMA-IR), insulin dose (ID) received, serum insulin antibody (IA), and C-peptide (CP) were tested. Out of 4054 collected articles, 14 RCTs (total 663 subjects) were eligible for inclusion. The pooled results obtained using a random-effects model showed a statistically significant decrease in HbA1c levels (MD, −1.24, 95% confidence interval (CI): −2.00, −0.48, p < 0.001 heterogeneity (I2) = 94%) and ID received (MD, −16.72, 95% CI: −22.09, −11.35 p < 0.00001, I2 = 90%), with a clear tendency was shown, but non-significant, to decrease FBG (MD, −23.32, 95% CI: −47.33, 0.70, p = 0.06, I2 = 98%) in patients with diabetes who consumed CM in comparison to those on usual care. Conversely, the consumption of CM did not show significant reductions in the rest of the glucose homeostasis parameters. Subgroup analysis revealed that patients with T2DM were more beneficially affected by CM intake than those with T1DM in lowering FBG, while patients with T1DM were more beneficially affected by CM intake than those with T2DM in lowering HbA1c. Both fresh and treated (pasteurized/fermented) CM gave similar beneficial effects in lowering HbA1c. Lastly, a relatively superior effect for longer duration on shorter duration (>6 months, ≤6 months, respectively) of CM intake is found in lowering HbA1c. To conclude, long-term consumption of CM by patients with diabetes could be a useful adjuvant therapy alongside classical medications, especially in lowering the required insulin dose and HbA1c. Due to the high heterogeneity observed in the included studies, more controlled trials with a larger sample size are warranted to confirm our results and to control some confounders and interfering factors existing in the analyzed articles.
A Material Model Approach on the Deflection and Crack Pattern in Different Panels of the RCC Flat Plate using Finite Element Analysis

Three reinforced cement concrete (RCC) flat plate panels, namely interior, edge, and corner panels, were considered for evaluating the deflection and crack development from the column. In this study, a numerical analysis was conducted for a steel fibre-reinforced flat plate with steel fibre volumes of 0.3% and 0.4%. The study was conducted on real- and scaled-sized flat plates. We used the ABAQUS software to model and evaluate the deflection and crack patterns. An experimental study was conducted on the scaled-sized specimens to validate the finite element analysis (FEA) results. This study presents the punching shear behaviour of various panels of a flat plate with and without steel fibres. The deflection values obtained from the FEA and experiment were compared, and we found that the interior panel exhibited better results when compared to edge and corner panels. A minimum of three sided support is preferred for the stability of a larger-sized flat plate. The interior panels provided better strength and load-bearing capacity when compared to edge and corner panels. Crack patterns for different panels of a flat plate with different steel fibre volumes were analysed by comparing the FEA and experimental results. The development of cracks moved away from the column face on addition of steel fibres and changed its brittle nature. The results indicate that the crack developed from the column face is away from the critical distance d/2 from the slab-column junction (specimens with fibre), further demonstrating the stability of the structure. Doi: 10.28991/CEJ-2022-08-03-05 Full Text: PDF
RESEARCH BEHAVIOR IN HIGHER EDUCATION: A COMPARATIVE ANALYSIS OF UNIVERSITIES AND POLYTECHNICS STUDENTS IN THE SOUTH-EAST OF NIGERIA

Research in Nigerias institutions of higher learning, including the universities and polytechnics, has consistently proved to be below expectation given the importance of research to the growth and development of the country. Although, the constraints impeding the realization of research goals in the higher education ecosystem have mainly been captured in the literature. However, there is a growing concern about the research behavior of scholars in higher education in Nigeria. Thus, the primary purpose of the current study is to compare research behavior between the university and polytechnic lecturers in southeast Nigeria. Ninety-six academic staff pooled from public tertiary institutions in the Enugu and Ebonyi States of Nigeria completed a self-report measure. The mean, standard deviation score, and t-test result revealed a statistically significant difference between the university and polytechnic scholars on research behavior. Thus, the result indicated that university lecturers have more positive research behavior than their polytechnic counterparts.
BIFASCICULAR BLOCK REVEALING STEINERTS MYOTONIC DYSTROPHY

Steinerts disease or myotonic dystrophy type 1 is a genetic neuromuscular disorder with autosomal dominant transmission. It leads to multisystemic damage, including a cardiac localization that is life-threatening.We report the case of a 55 year old patient, without cardiovascular risk factors, with a history of distal muscle damage since the age of 25 years, in his family history we find a brother followed for an unlabelled skeletal muscle damage.He consulted for exertional dyspnea and lipothymic discomfort. The clinical examination revealed a decrease in muscle strength in the lower limbs with amyotrophy. Walking is difficult with the help of crutches and the patient uses a wheelchair. The neurological investigation concluded in Steinerts myotonic dystrophy on the electromyogram.The patients ECG showed a bifascicular block consisting of a left anterior hemiblock and a complete right bundle branch block. The echocardiography did not show any structural abnormalities but found a disturbance of the LV relaxation on the mitral profile.The electrophysiological exploration carried out for the measurement of infrahisical conduction revealed a long HV at 100ms indicating the implantation of a double chamber stimulation.The interest of reporting this case was to underline the importance of screening for cardiac damage of rhythmic origin. But also to inform with the help of literature data the incidence of these forms and the place of cardiac stimulation in the prevention of sudden death in steinerts myotonia.
Cancer Statistics in Korea: Incidence, Mortality, Survival, and Prevalence in 2019

Purpose The current study provides national cancer statistics and their secular trends in Korea, including incidence, mortality, survival, and prevalence in 2019. Materials and Methods Incidence, survival, and prevalence rates of cancer were calculated using the Korea National Cancer Incidence Database, from 1999 to 2019, with survival follow-up until December 31, 2020. Deaths from cancer were assessed using causes-of-death data obtained from Statistics Korea. Results In 2019, newly diagnosed cancer cases and deaths from cancer were reported as 254,718 (age-standardized rate [ASR], 275.4 per 100,000) and 81,203 (ASR, 72.2 per 100,000), respectively. For the first time, lung cancer (n=29,960) became the most frequent cancer in Korea, excluding thyroid cancer. The overall cancer incidence rates increased by 3.3% annually from 1999 to 2012, and decreased by 5.3% annually from 2012 to 2015, thereafter, followed by nonsignificant changes. The incidence of thyroid cancer increased again from 2016 (annual percentage change, 6.2%). Cancer mortality rates have been decreasing since 2002, with more rapid decline in recent years (annual decrease of 2.7% from 2002 to 2013; 3.3% from 2013 to 2019). The 5-year relative survival between 2015 and 2019 was 70.7%, which contributed to prevalent cases reaching over 2 million in 2019. Conclusion Cancer survival rates have improved over the past decades, but the number of newly diagnosed cancers is still increasing, with some cancers showing only marginal improvement in survival outcomes. As the number of cancer survivors increases, a comprehensive cancer control strategy should be implemented in line with the changing aspects of cancer statistics.
Analysis of Spatial Distribution of CVD and Multiple Environmental Factors in Urban Residents

Cardiovascular disease (CVD) poses a serious threat to urban health with the development of urbanization. There are multifaceted and comprehensive influencing factors for CVD, so clarifying the spatial distribution characteristics of CVD and multiple environmental influencing factors is conducive to improving the active health intervention of urban environment and promoting the sustainable development of cities The spatial distribution characteristics of CVD deaths in a certain district, Bengbu City, Huaihe River Basin, China, in 2019 were explored, and the correlation between multiple environmental factors and CVD mortality was investigated in this study, to reveal the action mechanism of multiple environmental factors affecting the risk of mortality. Relevant studies have shown that (1) CVD deaths are characterized as follows: male deaths are more than females; the mortality is higher in those of higher age; most of them are unemployed; cardiocerebral infarction is the main cause of death; and the deaths are mainly distributed in the central city and near the old urban area. (2) The increased CVD mortality can be attributed to the increased density of restaurants and cigarette and wine shops around the residential area, the increased traffic volume, the dense residential and spatial forms, the low green space coverage, and the distance from rivers. Therefore, appropriate urban planning and policies can improve the active health interventions in cities and reduce CVD mortality.
Comparing measurements of violent crime in local communities: a case study in Islington, London

ABSTRACT Police-recorded crime data are prone to measurement error, affecting our understanding of the nature of crime. Research has responded to this problem using data from surveys and emergency services. These data sources are not error-free, and data from different sources are not always easily comparable. This study compares violent crime data recorded by police, ambulance services, two surveys and computer simulations in Islington, London. Different data sources show remarkably different results. However, crime estimates become more similar, but still show different distributions, when crime rates are calculated using workday population as the denominator and log-transformed. Normalising crime rates by workday population controls for the fact that some data sources reflect offences’ location while others refer to victims’ residence, and log-transforming rates mitigates the biasing effect associated with some multiplicative forms of measurement error. Comparing multiple data sources allows for more accurate descriptions of the prevalence and distribution of crime.
Foliar application of salicylic acid intensifies antioxidant system and photosynthetic efficiency in tomato plants

: Tomatoes are the most important and grown vegetable crop in the world. The salicylic acid (SA) application could improve crop yields due the positive physiological effects of this plant growth regulator. Thus, this study aimed to evaluate the possible effects of SA application on leaf regarding the intensification of antioxidant enzymes activities, chlorophyll a fluorescence, gas exchange, and tomato production against environmental stress. This experiment was conducted by the use of Colossal tomato hybrid in a protected environment between July and December 2019. Therefore, a randomized block design with five SA doses was used, as follows: 0; 0.5; 1; 1.5, and 2 mM. Then, applications were performed weekly from 15 to 60 days after transplantation (DAT). At the 45 th and the 60 th DAT, the enzymes activities were analysed, such as superoxide dismutase (SOD), catalase activity (CAT) and peroxidase (POD), lipid peroxidation, proline content, chlorophyll a fluorescence, gas exchange, and plant height. At the end of the experiment, fruit weight, total and commercial production were also evaluated. Results indicated that foliar application of SA reduced the environmental stress in plants through the intensification of antioxidant system that reduced lipid peroxidation and qNP and increased the efficiency of photosystem II and ETR. Furthermore, gas exchange was also influenced by the action of SA in g s , favouring A and A / Ci . The SA dose between 0.5 and 0.8 mM positively enabled the total and commercial production of tomatoes. Therefore, foliar application of SA reduced oxidative damage, and increased photosynthetic efficiency and fruit production.
Cognitive and Adaptive Effects of Early Growth Hormone Treatment in Prader–Willi Syndrome Patients: A Cohort Study

Background: Prader–Willi Syndrome (PWS) is a genetically based neurodevelopmental disease characterized by obesity, hyperphagia, and mild to moderate intellectual disability. Treatment with growth hormone (GH) could provide cognitive benefits. The objective of the present study was to compare the cognitive and adaptive performance of 31 patients with genetically confirmed PWS grouped in two cohorts, one treated with GH before 2 years old (Group 1) and the other receiving the treatment later (Group 2). Method: We compared two variables necessary to diagnose intellectual disability: intellectual performance, using the Weschler scales, and adaptive behavior, using the DABS scale. The scores were analyzed by means of non-parametric statistical tests. Results: Group 1 (n = 10) obtained higher and statistically significant scores in Total Intelligence Quotient (TIQ), General Ability Index (GAI), and General Adaptive Behavior (GAB), implying better cognitive and adaptive performance compared to Group 2. Conclusions: Treatment with GH should be administered in the early stage of development (before 2 years old) to obtain greater benefits at the cognitive and adaptive levels.
Are they ready? Moderators of the correlation between work affect and job satisfaction felt by teachers of inclusive and special schools

BACKGROUND The study aimed to determine to what extent emotions experienced at work are predictors of the level of teachers’ job satisfaction. The moderating role of the type of school – inclusive and special – for this correlation was also analysed. PARTICIPANTS AND PROCEDURE The study involved 214 teachers at three levels of inclusive and special schools (primary, middle and high) attended by pupils with special educational needs. The respondents represented various age groups. The study used the Work Affect Scale and the Satisfaction with Job Scale. RESULTS The results clearly suggest that the emotions teachers experience at work are a strong predictor of their job satisfaction – positive emotions imply high job satisfaction whereas negative emotions imply low job satisfaction. This regularity exists in both the responding teacher groups. It was determined that the type of an institution does not significantly affect the above predictive attribute of organizational work affect. CONCLUSIONS Positive work-related emotions and average and high job satisfaction felt by ca. 2/3 of the responding inclusive and special school teachers suggest that both these groups are fully ready for high-quality education for all.
Word imageability is associated with expressive vocabulary in children with autism spectrum disorder

Background & aims Throughout typical development, children prioritize different perceptual, social, and linguistic cues to learn words. The earliest acquired words are often those that are perceptually salient and highly imageable. Imageability, the ease in which a word evokes a mental image, is a strong predictor for word age of acquisition in typically developing (TD) children, independent of other lexicosemantic features such as word frequency. However, little is known about the effects of imageability in children with autism spectrum disorder (ASD), who tend to have differences in linguistic processing and delayed language acquisition compared to their TD peers. This study explores the extent to which imageability and word frequency are associated with early noun and verb acquisition in children with ASD. Methods Secondary analyses were conducted on previously collected data of 156 children (78 TD, 78 ASD) matched on sex and parent-reported language level. Total expressive vocabulary, as measured by the MacArthur Bates Communicative Development Inventory (MB-CDI), included 123 words (78 nouns, 45 verbs) that overlapped with previously published imageability ratings and word input frequencies. A two-step hierarchical linear regression was used to examine the relationship between word input frequency, imageability, and total expressive vocabulary. An F-test was then used to assess the unique contribution of imageability on total expressive vocabulary when controlling for word input frequency. Results In both the TD and ASD groups, imageability uniquely explained a portion of the variance in total expressive vocabulary size, independent of word input frequency. Notably, imageability was significantly associated with noun vocabulary and verb vocabulary size alone, with imageability explaining a greater portion of the variance in total nouns produced than in total verbs produced. Conclusions Imageability was identified as a significant lexicosemantic feature for describing expressive vocabulary size in children with ASD. Consistent with literature on TD children, children with ASD who have small vocabularies primarily produce words that are highly imageable. Children who are more proficient word learners with larger vocabularies produce words that are less imageable, indicating a potential shift away from reliance on perceptual-based language processing. This was consistent across both noun and verb vocabularies. Implications Our findings contribute to a growing body of literature describing early word learning in children with ASD and provide a basis for exploring the use of multisensory language learning strategies.
A novel dynamic contact angle model of lattice Boltzmann method for water droplet impact on proton exchange membrane fuel cell channel surface

To predict water behavior accurately and explore water droplet impact on a proton exchange membrane fuel cell channel surface, a novel dynamic contact angle model was introduced. A two‐dimensional model of water droplet impact was established via the lattice Boltzmann method, and it was validated. Influences of equilibrium contact angle, sliding angle, lateral velocity, and longitudinal velocity were all explored. The results reveal that when droplet impact the channel surface, it appears in three states: spreading, rebounding, and moving. The model can capture the water‐air interface accurately. When the droplet impacts a hydrophobic wall, the droplet jumps up after rebounding, and eventually returns to its original shape. When the equilibrium contact angle increases, the spread factor gradually decreases, and the droplet keeps moving on the wall. With the increase of sliding angle, the spread factor gradually decreases, and the height of the droplet rebound also increases. The lateral velocity can cause the front end of the droplet to be elongated. As longitudinal velocity increases, spread factor increases, and relative distance gradually decreases.
Substitution of ‘small’ divalent cations (e.g. Mg) for Si and Al in the nepheline tetrahedral framework: 1. Calculation of atomic formulae and stoichiometry parameters

Abstract A recent review paper on nepheline solid solutions dealt mainly with sodic varieties from nepheline syenites and differentiated alkali basaltic sills. Excel spreadsheets were provided for recalculating cell formulae in terms of the stoichiometric parameters ΔAlcavity cation charge and ΔTframework charge and molecular percentages of the end-members Ne, Ks, Ca-nepheline and excess Si (Qxs). Small amounts of tetrahedral divalent species (usually <0.10 wt.% though with up to 0.33 wt.% MgO) were related to a stuffed-tridymite end-member of ideal formula K8Mg4Si12O32 (denoted KsT2+-nepheline), although the equations used to calculate these end-members only considered Si, Al and Fe3+ as tetrahedral framework species. Recently, K-rich nepheline and kalsilite which contain up 0.54 wt. % MgO have been found in some feldspar-free mafic potassic volcanic rocks from central Brazil. Equations have been developed to deal rigorously with the presence of significant amounts of Mg (and Mn) in recalculating nepheline solid-solution parameters. In two related communications reworked spreadsheets are provided with examples of their use. High quality microprobe analyses of nepheline and kalsilite from magmatic rocks must include analyses for Mg and Mn and, if possible, estimates of Fe2+ contents.
Elimination of Induced Hypoxic Regions in Depth of 3D Porous Silk Scaffolds by the Introduction of Channel Configuration

Development of large, clinically sized tissue constructs with efficient mass transport is a tremendous need in tissue engineering. One major challenge in large tissue-engineered constructs is to support homogeneous delivery of oxygen and nutrients throughout the tissue scaffold while eliminating induced hypoxic regions in depth. To address this goal, we introduced an especial channeled architecture on porous silk-based tissue scaffolds to improve supplying of oxygen to the cells in central regions of the scaffolds. Oxygen gradients were measured and evaluated in three scaffold prototypes, namely, one unchanneled and two channeled scaffolds with different channel diameters (500 μm and 1000 μm). The channels were introduced into the constructs using stainless-steel rods arranged uniformly in stainless-steel mold, a fabrication method that enables precise control over channel diameter and the distance between channels. During 2-week culture of G292 cells, the 1000 μm channeled scaffolds demonstrated higher oxygen concentration at the center compared to 500 μm channeled prototype; however, the oxygen concentration approached the same level around the last days of culture. Nevertheless, homogenous oxygen distribution throughout the 1000 μm channeled constructs and the consequence of higher cell proliferation at day 14 postseeding corroborate the efficient elimination of induced hypoxic regions; and therefore, it holds promise for clinically relevant sized scaffold especially in bone tissue engineering.
A New Hope

The analysis of desire ascriptions has been a central topic of research for philosophers of language and mind. This work has mostly focused on providing a theory of want reports, that is, sentences of the form ‘S wants p’. In this paper, we turn from want reports to a closely related but relatively understudied construction, namely hope reports, that is, sentences of the form ‘S hopes p’. We present two contrasts involving hope reports and show that existing approaches to desire fail to explain these contrasts. We then develop a novel account that combines some of the central insights in the literature. We argue that our theory provides an elegant account of our contrasts and yields a promising analysis of hoping.