Miracle-dz/UniFAR-FTUs huggingface dataset:
Autoimmune hemolytic anemia in COVID-19 patients, the « transmissible » direct Coombs test

Background: Like other viruses, the SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) appears to be responsible for several autoimmune complications. The occurrence of autoimmune hemolytic anemia has been described in several case reports. This AIHA was also noticeable by the important number of blood transfusions required for COVID-19 (coronavirus disease 2019) patients. By investigating RBC coating autoantibodies, this article attempts to clarify the autoimmune aspect of the anemia in the context of SARS-CoV-2 infection.
Atlas

Non-volatile main memory, such as memristors or phase change memory, can revolutionize the way programs persist data. In-memory objects can themselves be persistent without the need for a separate persistent data storage format. However, the challenge is to ensure that such data remains consistent if a failure occurs during execution. In this paper, we present our system, called Atlas, which adds durability semantics to lock-based code, typically allowing us to automatically maintain a globally consistent state even in the presence of failures. We identify failure-atomic sections of code based on existing critical sections and describe a log-based implementation that can be used to recover a consistent state after a failure. We discuss several subtle semantic issues and implementation tradeoffs. We confirm the ability to rapidly flush CPU caches as a core implementation bottleneck and suggest partial solutions. Experimental results confirm the practicality of our approach and provide insight into the overheads of such a system.
Adocus Kohaku, A New Species of Aquatic Turtle (Testudines: Cryptodira: Adocidae) from the Late Cretaceous of Kuji, Iwate Prefecture, Northeast Japan, with Special References to the Geological Age of the Tamagawa Formation (Kuji Group) LSID urn:lsid:zoobank.org:act:61376EEE-A386-416E-98AE-FF64FE2597

A nearly complete shell of the genus Adocus (Adocidae; Pan-Trionychia; Cryptodira; Testudines) was collected from the late Cretaceous (Turonian) Tamagawa Formation of Kuji Group at Kuji City, Iwate Prefecture, northeast Japan. This turtle shows unique features such as the loss of cervical scute, extreme expansion of marginal scutes overlying costal plates, and exclusion of the humeralpectoral sulcus from entoplastron. Thus, A. kohaku is erected as a new species. As A. kohaku shows most derived position of A. kohaku within this genus, morphological diversity of the genus Adocus seems to have occurred rather early in its evolution in Eastern Asia.
GazeMeter: Exploring the Usage of Gaze Behaviour to Enhance Password Assessments

We investigate the use of gaze behaviour as a means to assess password strength as perceived by users. We contribute to the effort of making users choose passwords that are robust against guessing-attacks. Our particular idea is to consider also the users’ understanding of password strength in security mechanisms. We demonstrate how eye tracking can enable this: by analysing people’s gaze behaviour during password creation, its strength can be determined. To demonstrate the feasibility of this approach, we present a proof of concept study (N = 15) in which we asked participants to create weak and strong passwords. Our findings reveal that it is possible to estimate password strength from gaze behaviour with an accuracy of 86% using Machine Learning. Thus, we enable research on novel interfaces that consider users’ understanding with the ultimate goal of making users choose stronger passwords.
The current and evolving European regulation of biosimilars: views from industry and medicines agency regulators

6 Background . 6 Aims . 6 Methods . 6 Results . 7 Conclusion . 7 RESUMÉ . 8 Baggrund . 8 Formål . 8 Metode . 8 Resultater . 9 Konklusion . 9 LIST OF ABBREVIATIONS . 11 TABLE OF CONTENTS . 12
CONGA

We present the design, implementation, and evaluation of CONGA, a network-based distributed congestion-aware load balancing mechanism for datacenters. CONGA exploits recent trends including the use of regular Clos topologies and overlays for network virtualization. It splits TCP flows into flowlets, estimates real-time congestion on fabric paths, and allocates flowlets to paths based on feedback from remote switches. This enables CONGA to efficiently balance load and seamlessly handle asymmetry, without requiring any TCP modifications. CONGA has been implemented in custom ASICs as part of a new datacenter fabric. In testbed experiments, CONGA has 5x better flow completion times than ECMP even with a single link failure and achieves 2-8x better throughput than MPTCP in Incast scenarios. Further, the Price of Anarchy for CONGA is provably small in Leaf-Spine topologies; hence CONGA is nearly as effective as a centralized scheduler while being able to react to congestion in microseconds. Our main thesis is that datacenter fabric load balancing is best done in the network, and requires global schemes such as CONGA to handle asymmetry.
DESIGN AND DEVELOPMENT OF A NEW APPROACH TO WRIST REHABILITATION

Wrist injuries are a very common type of pathology that can compromise most daily tasks. Conventional therapy is dependent on the availability of physiotherapists as well as devices designed for this purpose. Conventional devices do not accompany the patient throughout their rehabilitation process, requiring their constant replacement. Vibratory therapies emerged in recent years and have demonstrated several benefits in this area. However, there are few vibratory devices designed for wrist rehabilitation. In this paper, we propose two different portable and active models for wrist rehabilitation based on vibratory therapy for wrist rehabilitation. The first model has a cylindrical shape and the second model has a dumbbell shape. The results obtained showed that vibratory therapy can assist the wrist rehabilitation because it promoted improvements in joint amplitude gain in all wrist movements. Furthermore, the second device demonstrated higher joint gains than the first device. In addition, the results obtained from the measurement of accelerations demonstrate that the natural frequencies of both devices are adequate for wrist and forearm rehabilitation as well as the mode of vibration. There are differences between what the simulations predicted and what was obtained in practice in terms of natural frequency values.
NITRIC OXIDE PATHWAY AS A POTENTIAL THERAPEUTIC TARGET IN COVID-19

The Covid-19 viral infection is linked to a severe pulmonary reaction, leading to an acute lung injury in a large percentage of affected patients Various inflammatory pathways regulated by SARS-CoV-2 are under-investigated Some potential therapeutic options aimed to alleviate the inflammatory response of SARS-CoV-2 infection are involving different strategies for blocking the activation of its binding receptors on host cells and immunomodulation Given that excessive lung inflammation is likely to cause death in Covid-19 patients, using nitric oxide (NO) pathway to mitigate this risk appears to be a reasonable approach to avoid serious lung injury Such therapy could be paired with systemic immunomodulatory therapy to combat the multiple organ damage of Covid-19 Therefore, regulating the NO pathway has a potential therapeutic strategy to minimize the mortality of SARS-CoV-2 infection © 2020, Romanian Society for Pharmaceutical Sciences All rights reserved
Recovery efficiencies of nitrogen, phosphorus and potassium of the garlic crop

ABSTRACT Garlic plants demand high quantities of nutrients, and fertilizers recommendations are necessarily evaluated for the availability of attributes such as recovery efficiency. The objective of this study was to evaluate the recovery efficiencies of nitrogen (N), phosphorus (P) and potassium (K) by micropopagated and conventionally propagated garlic plants. Two experiments were conducted in a greenhouse containing a sample of a Red Yellow Latosol, arranged in randomized blocks with five replications. Treatments consisted of four combinations of nutrients (kg per hectare): complete NPK (240-1200-550), without N (0-1200-550), without P (240-0-550) and without K (240-1200-0). Micropopagated plants maintained adequate contents of N, P, and K, as well as good growth and development even without nutrients application; however, the depletion of N and K impaired the productivity of these plants. In both cultivations, recovery efficiencies of N, P and K were low and closely related to the garlic propagation.
Einfluß der Höhe am Stamm auf die Verteilung der Raumdichte des Holzes in Fichtenbeständen

i. Problemstellung In einer früheren Untersuchung (Stern 1961) war festgestellt worden, daß die Himmelsrichtung auf die Verteilung der Raumdichte des Holzes in Fichtenbeständen einen geringen Einfluß hat, den man in der Praxis vernachlässigen kann. Die vorliegende Arbeit hat den Einfluß der Höhe am Stamm, an der die Probe entnommen wird, auf die Raumdichte zum Gegenstand. Das Ziel der Untersuchungen war es dabei festzustellen, welche Zuverlässigkeit in der Praxis anwendbare Verfahren zur Schätzung der mittleren Raumdichte von Fichtenstämmen haben, die mit einer einzigen oder mit einigen wenigen Proben je Stamm auskommen müssen. Es kann sich dabei darum handeln, die Raumdichte liegender, Stämme oder stehender Bäume festzustellen; Vergleiche dieser Art sind zwischen Beständen oder zwischen Bäumen des gleichen Bestandes möglich. Die Abnahme der Raumdichte des Holzes von Fichtenstämmen mit zunehmender Höhe am Stamm ist seit langem bekannt und von vielen Autoren beschrieben worden (zuerst von Sani o, 1873, bez. späterer Literatur vgl. Hildebrandt, 1960). Für den vorliegenden Zweck kann die biologische Erklärung des Phänomens außer Betracht bleiben. Es genügt, wenn wir es als „Variationsursache" und im Zusammenhang mit anderen Variations Ursachen sehen. Um das tun zu können, stellen wir uns das Holz eines gleichaltrigen Fichtenbestandes in kleine Holzproben zerlegt vor. Die Variation des Raumgewichts dieser Proben wird dann bestimmt durch Unterschiede zwischen den Baummitteln, Unterschiede zwischen Proben am gleichen Baum. Für die Unterschiede zwischen Baummitteln werden genetische und Umwelteffekte verantwortlich gemacht, für die Unterschiede zwischen Proben vom gleichen Baum ihre Position am Stamm und eine gerade für die jeweilige Probe anzunehmende Umweltabweichung. Von der Möglichkeit des Vorkommens von Reaktionsholz soll hier abgesehen werden; man kann es im Experiment weitgehend ausschalten. (Über eine „biologisch richtige" Probenahme vgl. Richardson, 1961, und die dort angegebene Literatur.)
Therapeutic effects of growth factor cocktail (CellcurinTM) containing FGF5s (fibroblast growth factor 5 short) and NMN (nicotinamide mononucleotide) in patients with androgenetic alopecia: A split study

Background: Growth Factor Cocktail (GFC), which contains growth factors and cytokine, has been gradually gaining attention as a new treatment for hair loss. Several studies reported the effectiveness of GFC on hair regrowth via microneedles; however, studies regarding formulations with fibroblast growth factor 5 short (FGF5s) and nicotinamide mononucleotide (NMN) have not been conducted. Objective: This study aimed to investigate the effect of treatment with microneedle technology by adding FGF5s and NMN to GFC in patients with androgenetic alopecia (AGA). Methods: In this study, AGA patients were treated six times for a total of 3 months at 2-week intervals from the first visit. The scalp was divided into two sections at the time of treatment; the right side was treated with GFC with FGF5s and NMN, and the left were treated with normal saline, with microneedles to a depth of 0.8 mm. A total of 20 patients (11 males and 9 females) were included in the study. Clinical photographs and phototrichogram were performed before and 2 weeks after treatment to determine the final treatment effect. Results: The phototrichogram images of the scalp treated with GFC for 3 months showed increased hair density and diameter. In contrast, there was no change in hair density and diameter in the scalp treated with normal saline. Conclusion: GFC with FGF5s and NMN with microneedling is an effective and safe treatment of androgenetic alopecia. Future studies with more thorough investigations in controlled clinical settings are warranted. *Correspondence to: Byung In Ro, M.D., Ph.D., Invited Professor, Department of Dermatology, Myongji Hospital, Hanyang University College of Medicine, Goyang 10475, Korea, Tel: +82-31-810-7050; Fax: +82-31-810-7057; E-mail: drro@mjh.or. kr
Machine Learning with Applications

When overpopulated cities face frequent crowded events like strikes, demonstrations, parades or other sorts of people gatherings, they are confronted to multiple security issues. To mitigate these issues, security forces are often involved to monitor the gatherings and to ensure the security of their participants. However, when access to technology is limited, the security forces can quickly become overwhelmed. Fortunately, more and more important smart cities are adopting the concept of intelligent surveillance systems. In these situations, intelligent surveillance systems require the most advanced techniques of crowd analysis to monitor crowd events properly. In this review, we explore various studies related to crowd analysis. Crowd analysis is commonly broken down into two major branches: crowd statistics and crowd behavior analysis. When crowd statistics determines the Level Of Service (LoS) of a crowded scene, crowd behavior analysis describes the motion patterns and the activities that are observed in a scene. One of the hottest topics of crowd analysis is anomaly detection. Although a unanimous definition of anomaly has not yet been met, each of crowd analysis subtopics can be subjected to abnormality. The purpose of our review is to find subareas, in crowd analysis, that are still unexplored or that seem to be rarely addressed through the prism of Deep Learning.
Assessment of Risk Factors for Severe Illness in Hospitalized CovId-19 Patients at a Tertiary Care Hospital.

Background: COVID-19 -19 is caused by severe acute respiratory syndrome coronavirus (SAR-COV-2). Identification of risk factors for severe illness helps in stratification of patients who may benefit from aggressive management strategies and early intervention.We aim to assess the risk factors for severe illness in patients admitted with COVID 19 infection. Methods: We conducted a retrospective observational study of 802 patients with confirmed COVID-19 admitted to our tertiary care hospital. Univariate and multivariate logistic regression were used to identify determinants for disease severity. Results: Of 802 hospitalized patients, severe COVID-19 infection was noted in (n= 537) (67%) patients. Patients with severe infection were significantly more likely to have hypertension, diabetes, and chronic pulmonary disease and had significantly higher white blood cell counts, NLR and decreased haemoglobin than patients with non severe infection. In multivariable logistic regression analysis, risk factors for severe infection included pre-existing hypertension (OR 2.29, 95% CI; (1.532-3.423), longer duration of symptoms before hospitalization (OR:1.158,95% CI(1.098-1.221),P<0.001) and Neutrophil lymphocyte ratio(NLR) >3. 8(OR, 1.101,95% CI (1.068-1.135); P<0.001). ROC curve for NLR shows that NLR at a cut off more than 3.8 has sensitivity of 80.5% and specificity of 58% in predicting severe illness. Conclusions: Patients with pre-existing hypertension, longer duration symptoms before hospitalization and high NLR (>3.8) needs early intervention to prevent the potential development of severe COVID-19.
Assessment of nutritional quality in the tissue of euryhaline fish tank goby Glossogobius giuris, hamilton 1822 caught from Vembanad Lake, Kerala, India

The present study was aimed to analyse the biochemical composition emphasise on Amino acids, protein with good amino acid content and minerals of Tank Goby Glossogobius giuris, native to fresh water to brackish water (Euryhaline). It is an unexploited fish commonly found in brackish water especially rich in Vembanad Lake, Kerala, India. Proximate composition of fish includes moisture 80.52%, protein 14.81%, Fat 2.82%, and Ash 1.08% respectively. Amino acids in the fish are divided in to three Essential, Conditionally essential and Non-Essential Amino acids. Among the essential amino acids Histidine (His) 1745.4 mg/100g was the most abundant. Isoleucine (Ile) and Leucine (Leu) had the lowest essential amino acid. Conditionally essential amino acids showed high percentage of Cysteine (18.54%) followed by Glycine (Gly) 5.9%. Alanine (2045.5 mg/100g) was found most significant concentration amongst the Non-essential amino acids. Significant amount of mineral, Phosphorous (402 mg/100g), Potassium (356.1 mg/100g), Calcium (340.8 mg/100g), Sodium (73.2 mg/100g) and Iron (1.5 mg/100g) reported in Tank goby. The heavy metals illustrated were Copper (0.033 ppm), Manganese (5.3 ppm), Zinc (17.21 ppm), Magnesium (154.1 ppm), Mercury (0.0035 ppm) and Chromium (15.8 ppm) respectively. The knowledge about the biochemical composition of the fish enhances the utility of the fish as good source of quality protein and amino acids.
Protein-protein interaction analysis reveals a novel function of the lhx 1 transcription factor in zebrafish

Normal embryonic development requires the coordinated expression of many genes. The temporal and spatial expression of these genes is regulated by transcription factors. The LIM homeodomain (LIM-HD) family of transcription factors plays important roles in the formation of the nervous system, reproductive tract, and kidney. lhx1 is a member of the LIM-HD family and is expressed in zebrafish kidney stem cells during development and regeneration. Its interaction with ldb1 has been shown to be important for its activation. However, no other protein is known to interact with lhx1. In this report, we set out to identify new interacting proteins and discovered for the first time that lhx1 can interact with itself to form a dimer. This provides a better understanding of the molecular function of lhx1 and may contribute to designing therapies for diseases caused by lhx1 malfunction.
AN EMPIRICAL ANALYSIS OF EFFECT OF CAPITAL STRUCTURE ON FIRM PERFORMANCE: EVIDENCE FROM MICROFINANCE BANKS IN NIGERIA

Issues surrounding capital structure and performance which have been widely debated in the finance literature, yet there has not been consensus as to how composition of firm‘s capital impact on firm performance including Nigeria. Thus this study investigated the relationship between capital structure and firm performance in the microfinance banking subsector in Nigeria from 2009 to 2018. The study employed explained variables (debt to equity ratio, long term debt ratio and total debt ratio) representing capital structure and the explanatory variable (return on equity) representing firm performance. Descriptive statistics and regression technique were used for the analysis. The results revealed a negative and insignificant relationship between Debt to equity ratio and return on equity, a positive and insignificant relationship between Long term debt ratio and return on equity and a positive and significant relationship between Total debt ratio and return on equity. The results also indicated that F-statistic is 37.16701 with a probability of 0.026372 indicating that the combined effect of the explained variables on firm performance represented by return on equity is statistically significant. It is therefore recommended that microfinance banks in Nigeria and beyond should devise strategies that are effective to expand their debt profile in order to achieve better performance.
52_57_LONG RUN STOCK PERFORMANCE OF MALAYSIAN ACQUIRERS

In this study, we focus on Malaysia, a developing e conomy where many firms are controlled by families. The sample is composed of acquisitions during the period 2000-2013. We find that on average acquiring firms neither create nor destroy long term values after controlling for the performance of a control group. This resul t hows that investors reacted rationally in valuing the bidding firms after the announcements o f the completions of the acquisitions. Thus, at least in the long run performance of acqui sitions, the capital market in Malaysia is informationally efficient.
Analyzing farmers’ perception towards integrated farming system in Madhya Pradesh

This paper is concerned with the Farmers Perception about utility of Integrated Farming System apropos in Mandla district of Madhya Pradesh was conducted on 250 small and marginal tribal farmers. Perception is mental organization and understanding of sensory information. It is the opinion expressed by the farmers. The farmer’s perception about IFS was based on two-point continuum viz. yes/no; complex/simple, complex/cheap, quick/slow, risky/safe, more secured/ less secure and agree/ disagree with a score of 1 and 0 respectively. The selected IFS practicing farmers have been interviewed personally with the help of a well structured and pre-tested interview schedule. Results revealed that, majority 93.00 per cent of the farmers as IFS programme increase the employment opportunities to the rural people were recorded rank (I) of the respondents and while 28.00 per cent of the respondents felt that, how risky it is adopt of IFS apropos were recorded very least statements and rank (XIII) of the respondents.
IS THIS MY COUNTRY? IDENTIFICATION WITH NATIONAL SYMBOLS IN SERBS AND BOSNIAKS IN B&H

Although the war in B&H ended more than 20 years ago, ethnic tensions continue to be present. The aim of this article is to present the level and differences between Serbs and Bosniaks in identification with national symbols of B&H. The representative sample consisted of 1308 participants, 58.7% of Bosniak ethnicity, living in Bosnia & Herzegovina. The data is collected by IPSOS as a part of the project Strategies of symbolic nation-building in West Balkan states: intents and results. The results have shown that Bosniaks identify significantly more with all national symbols, including flag, anthem, coat of arms, holidays. They also consider B&H to be their patria significantly more than Serbs. Both groups estimate low level of quality of intergroup relationship. Bosniaks are more prone to express dual ethnic and national identity, while Serbs tend to identify themselves only with their ethnic group. The results are discussed in the light of social identity theory.
Qualitative and quantitative evaluation of the phytochemical constituents of three wood species in Ogun state, Nigeria

Studies on the phytochemicals of the stem wood of tropical trees are scarce, despite its importance to plant protection and preservation as most researches focused on their leaves and fruits. This research work aimed to qualitatively and quantitatively analyze the phytochemicals present in the stem wood of Gmelina arborea, Tectona grandis and Anogeissus leiocarpus. Freshly sawn timbers were collected from a local sawmill and then grounded into finely powdered wood samples. The powdered wood samples and its extracts were screened for the presence or absence of phytochemicals using standard methodologies. The qualitative screening revealed the presence of various secondary metabolites such as tannin, saponin, steroids, flavonoid, alkaoids and terpene in all the three species. The result also showed that Tectona grandis had the highest percentage of Alkaloid (7.5%), Tannin (4.95%), and Flavonoid (4.67%) while Anogeissus leiocarpus had the highest percentage of Saponin (3.06%) and Terpene (1.45%). This study established the fact that the three selected species studied have potentials in the industries for medicinal and anti-pathogenic usages.