Miracle-dz/UniFAR-FTUs huggingface dataset:
Clinical and Laboratory Profile of Dengue Fever in Elderly Patients Admitted in a Tertiary Hospital from 2013 to 2018

Philippines is among the top southeast Asian country that is endemic to Dengue Fever based on DOH reported cases from a reported 152,224 in 2017 to an increase in 216,190 in 2018. Most studies in the country are derived from the pediatric and/or young adult population hence, there is a dearth of data describing our elderly patient with dengue. This is a retrospective observational study of elderly individuals diagnosed with Dengue Fever admitted at St. Luke’s Medical Center, E. Rodriguez, Quezon City from January 1, 2013 to December 31, 2018. A total of 142 elderly were recorded; 65% are females. Hypertension (53.8%) and Diabetes mellitus were the most common comorbid conditions. Aside from fever (98%), the elderly patients presented most frequently with arthralgia and/or myalgia at 38.46% followed by cough (35.66%), generalized body malaise (32.17%), decreased appetite (31.47%), headache (25.8%), loose bowel movement (15.38%), petechial rash (13.97%), chills (13.99%), and colds (11.19%). Serologic evidence of plasma leakage was seen in 20 patients (14%) while 77 patients showed leukopenia (53.8%) with the lowest recorded WBC count of 1.2/μL; 69% had thrombocytopenia though only 12% were transfused with either platelet concentrate or PRBC. The most common electrolyte imbalance was mild hyponatremia (36%) followed by mild hypokalemia (28.8%). Liver and renal failures were also seen in some patients.
How Can Cultural Values and Entrepreneurship Lead to the Consideration of Innovation-Oriented or Non-Innovation-Oriented Countries?

This study provides an analysis of the existing relationship between culture, entrepreneurship, and orientation towards innovation at the national level. Drawing on the creation of an Artificial Neural Network, and using a sample of 37 countries, this paper aims to catalogue each country as innovation-oriented or non-innovation-oriented considering the six cultural dimensions proposed by Hofstede’s model and the country´s entrepreneurial activity. The results achieved suggest that three of the cultural dimensions—long-term orientation, individualism, and indulgence—are positively associated with the consideration of a country as innovation-oriented, but one of them—uncertainty avoidance—is associated with the consideration of a country as non-innovation-oriented. On the other hand, while power distance and masculinity do not seem to be significant variables in this analysis, the entrepreneurial activity rate is associated with countries classified as non-innovation-oriented. This study aims to shed light on the relationships between cultural values, entrepreneurship, and orientation towards innovation, providing valuable information for stakeholders, mainly those belonging to private sector and governments, when designing strategies aimed at creating favourable environments for the development of a country’s technology, research, and innovation.
Prevalence and impact of takotsubo syndrome in hospitalizations for acute ischemic stroke

Abstract Takotsubo syndrome (TTS) is characterized by acute and reversible left ventricular dysfunction with apical ballooning arising during acute stress situations. Acute ischemic stroke (AIS) is one of the known triggers of TTS; however, the impact of TTS on in-hospital outcomes of AIS remains unexplored. We utilized data from the National Inpatient Sample (2007–2014) to identify admissions for AIS with TTS and evaluated the temporal trends, baseline characteristics, in-hospital complications, length of stay, and all-cause mortality. Survey multivariable logistic regression was used to compute adjusted odds ratios (OR) and 95% confidence intervals (CI). An estimated 2242 (0.4%) TTS cases were identified among AIS hospitalizations (N = 4,392,471). The frequency of TTS was higher in elderly, white, and female patients. After adjustment for confounders, TTS incidence in AIS was associated with higher odds of in-hospital complications including cardiogenic shock (OR 8.84, CI 4.07–19.17, P < 0.001), cardiac arrest (OR 3.17, CI 1.57–6.42, P = 0.001), and venous thromboembolism (OR 1.68, CI 1.14–2.47, P = 0.008). Moreover, AIS hospitalizations with TTS showed higher odds of developing respiratory failure (OR 3.13, CI 2.42–4.05, P < 0.001) and requiring mechanical ventilation/intubation (OR 4.09, CI 3.14–5.32, P < 0.001) compared to the non-TTS cohort. The AIS-TTS cohort had a longer length of stay (8.59 vs 5.22 days), and their mortality rate was twice (10.2% vs 5.1%; P < 0.001) that of those without TTS. In conclusion, the prevalence of TTS in AIS remained ∼20 times higher than in the general inpatient population and predisposed AIS patients to worse inpatient outcomes. Further studies are needed to evaluate the impact of TTS on long-term outcomes in AIS.
Effects of Exogenous ABA on Cold Resistance and Tender Seedlings Growth of Winter Wheat Dongnongdongmai 1 in Cold Area

Dongnongdongmai 1 is the only winter wheat(Triticum aestivum L.) cultivar that can bear low temperature and grow normally in Heilongjiang province.This experiment used this material to investigate the effects of exogenous ABA on cold resistance as the material by adding with ABA(concentrations were 0,10-4、10-5、10-6、10-7mol/L)in the agar medium(3%) in dark(Temperature 2~4℃,training boxes tilt angle of 45°),then were investigated after 11 days.The results show that: ABA has significant impacts on cold resistance,the low concentration of ABA can increase the growth of wheat under low temperature,the high concentrations inhibit growth.For increasing the wheat cold resistance,the optimal concentration of ABA is 10-7mol/L.Treating the wheat seedlings in ABA optimal concentration(10-7mol/L)(leaves and roots spraying both) in the low temperature.Five days later,several physiological indicators related with the cold resistance were tested,the results showed that: seedling at cold temperatmes,the ABA can increase chlorophyll content,soluble sugar content and soluble protein content,improve the activity of SOD and decrease membrane permeability;the effects of root absorption is better than that of leaf-spraying.
Variation in medical management and neurosurgical treatment of patients with supratentorial spontaneous intracerebral haemorrhage

Introduction The role of surgery in spontaneous intracerebral haemorrhage (sICH) remains controversial. This leads to variation in the percentage of patients who are treated with surgery between countries. Patients and methods We sent an online survey to all neurosurgeons (n = 140) and to a sample of neurologists (n = 378) in Dutch hospitals, with questions on management in supratentorial sICH in general, and on treatment in six patients, to explore current variation in medical and neurosurgical management. We assessed patient and haemorrhage characteristics influencing treatment decisions. Results Twenty-nine (21%) neurosurgeons and 92 (24%) neurologists responded. Prior to surgery, neurosurgeons would more frequently administer platelet-transfusion in patients on clopidogrel (64% versus 13%; p = 0.000) or acetylsalicylic acid (61% versus 11%; p = 0.000) than neurologists. In the cases, neurosurgeons and neurologists were similar in their choice for surgery as initial treatment (24% and 31%; p = 0.12), however variation existed amongst physicians in specific cases. Neurosurgeons preferred craniotomy with haematoma evacuation (74%) above minimally-invasive techniques (5%). Age, Glasgow Coma Scale score and ICH location were important factors influencing decisions on treatment for neurosurgeons and neurologists. 69% of neurosurgeons and 80% of neurologists would randomise patients in a trial evaluating the effect of minimally-invasive surgery on functional outcome. Discussion Our results reflect the lack of evidence about the right treatment strategy in patients with sICH. Conclusion New high quality evidence is needed to guide treatment decisions for patients with ICH. The willingness to randomise patients into a clinical trial on minimally-invasive surgery, contributes to the feasibility of such studies in the future.
Risk of Pesticide Exposure on Impaired Level of Intelligence (IQ) of Children

The shallot cropping pattern applied by farmers in the village of Pasir Demak is very likely to cause pollution. Pesticide contamination in pregnant women in the first trimester (3 months) can result in fetal death, low birth weight, and impaired intelligence (IQ). Preliminary research conducted in 2016 found that elementary schooler who came from Pasir Village, Demak had low learning achievement. It was an observational study with a cross-sectional approach; the respondents were Elementary Schooler grades 4, 5, and 6 (107 people) and the mothers of the students (107 people). Thus, the total respondents were 214 people. The IQ assessment instrument used the SPM and CPM instruments. The level of pesticide poisoning from the mother was to measure blood Cholin Esterase levels using a tintometer, the data were then statistically analyzed using Chi Square and Odd Ratio for risk factors. There were significant differences on the level of intelligence of children including the planting system p=0.002; room area p=0.047; ventilation area p=0.041; type of pesticide p=0.001; spraying before harvest p=0.007; spraying after harvest p=0.008; storage place for crop yields p=0.039, while the variables that did not show significant difference were the playing environment p=0.848; gestational age p=0.190; contact to pesticides p=0.105 and age p=0.418. Pesticide contamination in pregnant women in the 1st trimester which the time to process formation and development of the brain in the Temporal lobe and Frontal lobe will experience impaired learning and memory (IQ). Keywords : Elementary schooler; Pesticide exposure; Level of intelligence.
Palaeoarchaean TTGs of the Pilbara and Kaapvaal cratons compared; an early Vaalbara supercraton evaluated

The continental crust that dominates Earth’s oldest cratons comprises Eoarchaean to Palaeoarchaean (4.0 to 3.2 Ga) felsic intrusive rocks of the tonalite-trondhjemite-granodiorite (TTG) series. These are found either within high-grade gneiss terranes, which represent Archaean mid-continental crust, or low-grade granite-greenstone belts, which represent relic Archaean upper continental crust. The Palaeoarchaean East Pilbara Terrane (EPT), Pilbara Craton, Western Australia, and the Barberton Granite-Greenstone Belt (BGGB), Kaapvaal Craton, southern Africa, are two of the best exposed granite-greenstone belts. Their striking geological similarities has led to the postulated existence of Vaalbara, a Neoarchaean-Palaeoproterozoic supercraton. Although their respective TTG domes have been compared in terms of a common petrogenetic origin reflecting a volcanic plateau setting, there are important differences in their age, geochemistry, and isotopic profiles. We present new zircon Hf isotope data from five granite domes of the EPT and compare the geochemical and isotopic record of the Palaeoarchaean TTGs from both cratons. Rare >3.5 Ga EPT evolved rocks have juvenile εHf(t) requiring a chondritic source. In contrast, younger TTG domes developed via 3.5 to 3.4 and 3.3 to 3.2 Ga magmatic supersuites with a greater range of εHf(t) towards more depleted and enriched values, trace element signatures requiring an enriched source, and xenocrystic zircons that reflects a mixed source to the TTGs, which variously assimilates packages of older felsic crust and a more juvenile mafic source. EPT TTG domes are composite and record multiple pulses of magmatism. In comparison, BGGB TTGs are less geochemically enriched than those of the EPT and have different age profiles, hosting coeval magmatic units. Hafnium isotopes suggest a predominantly juvenile source to 3.2 Ga northern Barberton TTGs, limited assimilation of older evolved crust in 3.4 Ga southern Barberton TTGs, but significant assimilation of older (Hadean-Eoarchaean) crust in the ca. 3.6 Ga TTGs of the Ancient Gneiss Complex. The foundation of the EPT is younger than that for the oldest components of the Eastern Kaapvaal. Although the broader prevailing Palaeoarchaean geologic framework in which these two cratons formed may reflect similar a geodynamic regime, the superficial similarities in dome structures and stratigraphy of both cratonic terranes is not reflected in their geochemical and age profiles. Both the similarities and the differences between the crustal histories of the two cratons highlights that they are formed from distinct terranes with different ages and individual evolutionary histories. Vaalbara sensu lato represents typical Palaeoarchaean cratonic crust, not in the sense of a single homogeneous craton, but one as diverse as the continents are today.
A generalized model for predicting the thermodynamic properties of clay minerals

A set of models for estimating the enthalpy of formation, the entropy, the heat capacity and the volume of dehydrated phyllosilicates is presented. The model for entropy and heat capacity estimation is essentially based on a method of decomposition into polyhedral units, similar to that published by Holland (1989). The model for predicting the enthalpy of formation is based on the electronegativity scale, as previously developed by Vieillard (1994a, 1994b). For the sake of consistency, the models are parameterized using the same critical selection of thermodynamic properties from the literature. This includes a set of direct measurements especially dedicated to clay minerals that had not been taken into account in previous calculation methods. The accuracy of the predictions is tested for each property. The verification tests are also carried out for minerals that include different chemical elements than the phases used to derive the model constants, especially lithium-bearing micas. Verification tests also concern the Gibbs energy function that combines contributions from both models. Finally, the models are used in order to propose a complete thermodynamic database for clay mineral end-members. The consistency of the stability domains calculated on the basis of these thermodynamic properties is investigated by drawing relevant predominance diagrams for some chemical systems of interest. The models proposed represent a significant improvement with respect to previous works as regards the global accuracy of the estimates and because the developments were realized and tested using the same set of minerals, whose properties had been collected through a critical selection of the literature.
Propagation and overturning of three-dimensional Boussinesq wave packets with rotation

Alain D. Gervais ,1,* Quinlan Ede,2 Gordon E. Swaters ,1 Ton S. van den Bremer ,3 and Bruce R. Sutherland2,4 1Department of Mathematical and Statistical Sciences, University of Alberta, Edmonton, Alberta T6G 2G1, Canada 2Department of Earth and Atmospheric Sciences, University of Alberta, Edmonton, Alberta T6G 2E3, Canada 3Department of Engineering Science, University of Oxford, Oxford OX1 3PJ, United Kingdom 4Department of Physics, University of Alberta, Edmonton, Alberta T6G 2E1, Canada
Research of the activities of the enterprises of the perfume and cosmetic industry of Ukraine

The perfumery and cosmetic industry of Ukraine is distinguished by its dynamic development and makes a significant contribution to the country’s economy. Several types of economic activities are involved in its functioning, including the development, research, production and sale of perfumery and cosmetic products, as well as the provision of cosmetic services to the population. The economic activity of each sector in the chain of creation, production and sale of cosmetic products/services determines both their individual success and the efficiency of the entire system as a whole. In this regard, the systematization and analysis of the indicators of economic activity of enterprises of each type of activity of the national cosmetic industry is an urgent task, the solution of which will reasonably determine the prospects for both the further development of this industry and the export potential of the Ukrainian economy as a whole. The aim of this work was to conduct a comprehensive study of the dynamics of the main indicators of Ukrainian enterprises of perfumery, cosmetic and related industries economic activity for the period 2010–2019 and determination of their development trends. The available data of the State Statistics Service of Ukraine, the Patent Office of Ukraine, as well as a database of scientific and professional publications publications were used as materials and methods. Retrospective, logical, research methods, as well as the method of content analysis were used. The results of a comparative analysis of the main indicators of the economic activity of business entities in the studied industry made it possible to establish trends in the development of this sector of the economy and substantiate the patterns observed at the present stage. Conclusions. The results of the study indicate that the production potential of the perfumery and cosmetic industry in Ukraine is promising, as well as significant opportunities for further development of the trade in these products and the provision of cosmetic services to the population.
Spatio‐temporal assessment of the hydrological drivers of an active deep‐seated gravitational slope deformation: The Vögelsberg landslide in Tyrol (Austria)

Spatio‐temporal variations of precipitation are presumed to influence the displacement rate of slow‐moving deep‐seated landslides by controlling groundwater recharge, pore‐water pressure and shear strength. Phases of landslide acceleration responding to long‐lasting rainfall and snowmelt events occur under site‐ and event‐specific time delays. Assessing groundwater recharge and simultaneous recording of landslide displacement in a sufficient spatial and temporal resolution is essential to deepen the understanding of mechanisms controlling a landslide's deformation behaviour and is indispensable when it comes to identifying and developing target‐oriented mitigation strategies. The objective of this study was to assess hydrological landslide drivers (solid and liquid precipitation, snowmelt and evapotranspiration) and to investigate their spatio‐temporal distribution in the context of movements recorded at the Vögelsberg landslide (Tyrol, Austria). Hydrometeorological variables were simulated using the AMUNDSEN (Alpine MUltiscale Numerical Distributed Simulation ENgine) hydroclimatological model and landslide movements were continuously monitored using an automated tracking total station. Area‐wide simulated time series of available water were used: (i) to separate them into single landslide triggering hydrometeorological events; (ii) to analyse spatio‐temporal patterns of water availability per triggering event including individual response times; (iii) to delineate an effective hydrological landslide catchment; and (iv) to identify relations between assessed water input and landslide displacement rate. For the observation period from 05‐2016 until 06‐2019 we identified three distinctive hydrometeorological events causing time‐delayed periods of landslide acceleration. Spatio‐temporal differences in water availability per triggering event result in spatially diverse response times varying from 20 to 60 days for rainfall‐triggered events and between 0 and 8 days for events triggered by snowmelt. Pronounced spatio‐temporal differences of snowmelt within the model domain were identified to offer a unique possibility to delineate the effective hydrological landslide catchment. While considering event‐specific time‐lags, logarithmic correlations between incoming water and landslide displacement rate become apparent.
Integrating Community Participation With Interpretative Phenomenological Analysis: Reflections on Engaging the Autism Community

Members of the autistic community have long advocated for more input into and participation with autism-related research. Currently, the power to determine the direction of autism-related research and knowledge production related to autism lies with non-autistic researchers, while the wishes and perspectives of the autistic community are largely ignored. There is a growing trend toward ethical autism-related research, however, in which the perspectives of all stakeholders, particularly those of autistic individuals, are sought and their expertise on autism is foregrounded. In a study exploring the experiences of childhood adversity and resilience among autistic adults, we strove to conduct our research in an inclusive and ethical way, by integrating participatory methods, such as community engagement to inform research design, and credibility checking with participants to confirm that the analysis resonated with their experiences. Five stakeholders, representing parents of children on the autism spectrum, professionals, and autistic community members were recruited to provide input into the research design and provide insight into autistic ways of communicating, interacting, and being. The recommendations generated through this community engagement were then integrated into an interpretative phenomenological analysis (IPA) framework and implemented with four adult autistic participants. Through reflection on the process of community engagement, development of research design, implementation of the study, and credibility checking, it is clear that incorporating participatory methods into IPA increases rigor and ensures that autistic perspectives are represented through research.
Camel (Camelus Dromedarius) Milk Antibodies Ameliorated Diethylnitrosamine-Induced Hepatocellular Carcinoma in Wistar Rats

Hepatocellular carcinoma (HCC) is an extremely aggressive solid tumor and relates to numerous cases of cancer-associated deaths globally. Current studies reveal that natural compounds retain various therapeutic effects. This study was aimed to investigate the beneficial antitumor effects of camel (Camelus dromedarius) milk antibodies (CM-IgG) on diethylnitrosamine (DENA)-induced hepatocellular carcinoma in male Wistar rats. Hepatocarcinoma was induced in rats using DENA (50 mg/kg, twice/week) for 2 weeks followed by CCl4 (1 ml/kg, trice/week) for 6 weeks. At week 17th, HCC-bearing rats were orally administrated CM-IgG (100 mg/kg, orally) daily for 4 weeks. Liver enzyme activities and levels of alpha-fetoprotein (AFP) were measured in serum. Lipid peroxidation, nitric oxide, reduced glutathione (GSH) levels and superoxide dismutase (SOD) activity were determined in liver homogenate. Histological analysis using hematoxylin and eosin stain was examined in liver tissues. Hepatic mRNA gene expression of placental glutathione-s-transferase (GST-P) was determined by qRT-PCR. Treatment HCC-bearing rats with CM-IgG significantly reduced liver injury biomarkers and attenuated oxidative stress as well as enhanced antioxidant status. Moreover, CM-IgG significantly alleviated hepatocellular morphology alterations and down-regulated GST-P gene expression levels in liver. Our results revealed the potential role of total immunoglobulin IgG purified from camel milk in amelioration of DENA-induced hepatocellular dysfunction and oxidative stress in hepatocarcinoma-bearing rats.
Flow injection spectrophotometric system for N-acetyl-L-cysteine determination in pharmaceuticals

A flow injection system with spectrophotometric detection is proposed for determining N-acetyl-L-cysteine in pharmaceutical formulations. In this system, N-acetyl-L-cysteine was oxidized by Fe(III) and the Fe(II) producedis spectrophotometrically monitored as Fe(II)-1,10-phenantroline complex at 510 nm. Under the optimum analytical conditions, the linearity of the calibration curve for N-acetyl-L-cysteine ranged from 3.5×10 - 6 to 4.3×10 - 4 M. The detection limit of 6.3×10 - 7 M and recoveries between 98.5 to 110% were obtained.