Miracle-dz/UniFAR-FTUs huggingface dataset:
Blood pressure and electrocardiographic profile of children with sickle cell anaemia in steady-state and vaso-occlusive crisis

Objective: To compare the cardiovascular features of patients with sickle cell anaemia (SCA) in steady-state with those in vaso-occlusive crisis (VOC) at the Wesley Guild Hospital (WGH). Design: A descriptive cross-sectional, matched, case-control study among children with SCA at the WGH, a tertiary health facility in southwest Nigeria.Setting: The participants were recruited from the children’s emergency unit and paediatric haematology clinic of the WGH.Participants: Consisted of 93 children with VOC (cases) and 93 age and sex-matched in steady state (controls), aged 5 – 15 years.Main outcome measures: Cardiovascular parameters, including pulse rate, blood pressure, and electrocardiographic profile, were assessed and compared using the appropriate statistical tests.Results: The mean (SD) age of the cases and controls were 8.8 (3.2) years and 9.0 (3.1) years, respectively (p= 0.106). There was no significant difference in the mean height of the groups. The mean pulse rate, diastolic, systolic, and mean arterial pressures were significantly higher in the cases than in the controls. A significantly higher proportion of the cases than the controls also had a higher frequency of heart blocks, prolonged QTc interval, ST elevation or depression, and T wave abnormality (p = 0.018, 0.039, 0.041, 0.009, respectively). The prevalence of chamber enlargements was not significantly different between the two groups.Conclusion: Cardiovascular dysfunction is worse during VOC when compared with steady state. Physicians should look for these dysfunctions in SCA children with VOC to reduce mortality from the disease.
Quality of pork after electron-beam irradiation: A meta-analysis study

Background and Aim: Irradiation has become a preferred method for pork preservation in recent years. Electron-beam irradiation is notably recognized for its feasibility and safety among various irradiation methods. This meta-analysis study aims to elucidate the impact of electron-beam irradiation on oxidation parameters, color, sensory attributes, and microbiological conditions in pork. Materials and Methods: A total of 79 data from 22 articles were aggregated into an extensive database. The irradiation dose ranged from 0 to 20 kGy in this current meta-analysis. The observed parameters encompassed oxidation, color, sensory attributes, and microbiological conditions. A mixed-model approach was used to perform the meta-data analysis, in which irradiation dose was treated as fixed effects and distinct studies (articles) as random effects. Results: Electron-beam irradiation resulted in an increase in thiobarbituric acid-reactive substances levels and peroxide-oxygen value of pork (p < 0.01). Conversely, total volatile-base-nitrogen values (p < 0.05) were observed. Following irradiation, the pH value, lightness (L*), redness (a*), and yellowness (b*) remained unaffected. Pork color tended to decrease after irradiation treatment (p = 0.095 and p = 0.079, respectively) at 7 and 14 days of storage. The irradiation process resulted in an increase in the values of texture and juiciness parameters (p < 0.05). However, electron-beam irradiation resulted in decreased overall acceptability (p = 0.089). In terms of microbiological status, electron-beam irradiation led to a reduction in the populations of Salmonella (p < 0.01), Escherichia coli (p < 0.01), Listeria monocytogenes (p < 0.05), and coliforms (p < 0.05) at 7 and 14 days of storage. Conclusion: Electron-beam irradiation enhances lipid peroxidation in porcine meat. The color of the meat remained unchanged after treatment. However, with regard to sensory properties, electron-beam irradiation showed a tendency to decreased overall acceptability. Most microbiological parameters decreased following electron-beam irradiation.
The Evolving Microbiome of Dental Caries

Dental caries is a significant oral and public health problem worldwide, especially in low-income populations. The risk of dental caries increases with frequent intake of dietary carbohydrates, including sugars, leading to increased acidity and disruption of the symbiotic diverse and complex microbial community of health. Excess acid production leads to a dysbiotic shift in the bacterial biofilm composition, demineralization of tooth structure, and cavities. Highly acidic and acid-tolerant species associated with caries include Streptococcus mutans, Lactobacillus, Actinomyces, Bifidobacterium, and Scardovia species. The differences in microbiotas depend on tooth site, extent of carious lesions, and rate of disease progression. Metagenomics and metatranscriptomics not only reveal the structure and genetic potential of the caries-associated microbiome, but, more importantly, capture the genetic makeup of the metabolically active microbiome in lesion sites. Due to its multifactorial nature, caries has been difficult to prevent. The use of topical fluoride has had a significant impact on reducing caries in clinical settings, but the approach is costly; the results are less sustainable for high-caries-risk individuals, especially children. Developing treatment regimens that specifically target S. mutans and other acidogenic bacteria, such as using nanoparticles, show promise in altering the cariogenic microbiome, thereby combatting the disease.
Comparison of nonwoven fabrics in terms of usefulness for oil spill combat

The petroleum substances (oil) spilled on the hard surface can be easily neutralized and collected by using powdery or granular sorbents. We are dealing with more difficult situation when oil spill appears on the soft ground or on the surface of the water. Extremely difficult is removing the oil from body of water polluted by dispersed one. In such cases useful are various balls, sleeves and mats filled by nonwovens. It is important to identify a material, which strongly absorbs different type of oil in a wide temperature range. At the same time, such material should have physical properties allowing easy and rapid contact with the spilled oil and then its removal from the environment. This paper provides an overview of impregnability of nonwoven fabrics made from two materials – polypropylene and cotton. The impregnability was tested against the water and the used lubricate oil. The tests were carried out by using experimental device constructed by members of the student’s scientific society at Faculty of Marine Engineering (Gdynia Maritime University). Principle of construction of testing device takes into account aspect of placing the sorbent in the package as well as possibility of repeating the experiment in precisely defined measurement conditions. Among tested materials, the best in terms of oil sorptivity proved to be polypropylene. The same material was the least absorbing water. It can therefore be assumed that this material is the most suitable for removing oil from the polluted water.
HYSTAR: Hydrology and Sediment Transport Simulation using Time-Area Method

A distributed approach can improve functionality of H/WQ (Hydrology and Water Quality) modeling by facilitating a way to ex plicitly incorporate spatial characteristics of a watershed into the model. The tim -area approach, with its intuitive and inherently distributed concept, provides a simp le method to simulate runoff mechanisms. This study developed a distributed mode l based on the time-area approach with the goal of improved utility and efficiency in H/WQ modeling. Uncertainty is always introduced into watershed mod eling because of imperfect knowledge and scale dependant spatial heterogeneity and temporal variability. Uncertainty analysis can provide a modeler, policy maker, and stakeholder with reliability information, better understanding, and better communication about the modeling results. This study quantified uncertainty of the model parameter and output through uncertainty analysis in order to assess ris k in watershed management. The main goal of this study was to develop a hydrology and s e iment transport model capable of routing overland flow using a time-area concept and providing reliability of the modeling results in a probabilistic manner through uncertain ty analysis. The HYSTAR (HYdrology and Sediment transport simula tion using Time-ARea method) model incorporates a modified Curve Number (CN) method and the newly devised time-area routing method to estimate runoff . HYSTAR is capable of simulating direct runoff, base flow, soil moisture, and sedime nt load in a distributed manner and in an hourly time step. In the model, the modified CN and a continuity equation are used to calculate infiltration of the routed runoff as well as rainfall on every overland cell. The effective direct runoff volume is distributed over downstream areas using the newly developed routing method. A direct runoff hydrograp h is constructed directly through the discrete convolution of the time-area histogram and the effective direct runoff volume
Policies for Individuals With Autism: Gaps, Research, and Recommendations

Autism spectrum disorder (ASD) is a complex neurodevelopmental disorder characterized by social, behavioral, and learning challenges. Individuals with autism and their families often struggle to get an appropriate diagnosis and continuation of specialty services, including general healthcare, mental health and transition services, special education, employment, and social and emotional support. This paper presents information about the current policies and support mechanisms that exist to help these individuals and their families. This paper identifies the gaps and recommends areas of improvement based on evidence-based research and current data. ASD is a lifelong disability without a cure, but by constructing robust policies and providing enhanced support, the quality of lives of those with ASD and their families can be improved.
The Impact of Social Entrepreneurship on Reducing Economic Inequality, Community Self-reliance, and Business Innovation in Urban Areas: A Case Study in Jakarta, Indonesia

With an emphasis on Jakarta, Indonesia, this study examines the relationship between company innovation, community self-reliance, and economic gap reduction and social entrepreneurship success in metropolitan settings. Using a quantitative methodology, 170 participants in the sample shared details about their entrepreneurial endeavors. The measurement model was validated by confirmatory factor analysis, which also confirmed the validity and reliability of the chosen constructs. Significant positive correlations between closing the economic gap, fostering community self-reliance, corporate innovation, and the effectiveness of social entrepreneurship were found using structural equation modeling. The findings were shown to be robust, and the distinctiveness of the constructs was confirmed using discriminant validity analysis and bootstrapping approaches. The model's strong explanatory ability was demonstrated by the R-Square values. The practical implications of the study's findings for policymakers, entrepreneurs, and communities in Jakarta pertain to creating an environment that is favorable for social entrepreneurship.
The Pain Characteristics and Caregiver Burden in Patients With Cancer-related Pain and their Associated Factors: A Cross-sectional Study

Introduction: Pain is the most common symptom among patients with cancer; the pain also affects their caregivers. Objective: This study aimed to explore the pain characteristics and caregiver burden in patients with cancer-related pain and their associated factors. Materials and Methods: This cross-sectional study was conducted on 240 patients and their caregivers (120 patients and 120 caregivers), who were chosen using the convenience sampling method. They completed face-to-face surveys, including information about sociodemographic and disease characteristics, the brief pain inventory, the pain beliefs questionnaire, and the Zarit burden interview scale. The descriptive statistics, frequency distributions, and multiple linear regression model were used to analyze the obtained data according to the two-tailed P<0.05. Results: The mean age of the patients was 58.79±13.46 years, and 50.8% were females. The mean age of the caregivers was 47.84±13.24 years, and 83.3% were females. The linear regression analyses showed demographic and clinical factors of patients were associated with pain severity (R2=0.326, P<0.001). In addition, these factors were associated with all sub-dimension of pain interference and pain beliefs (P<0.001). Furthermore, the linear regression model showed that patients' pain severity, pain interference and pain beliefs were predictive factors of caregiver burden (R2=0.266, P<0.001). Conclusion: These results will help health professionals understand the pain characteristics of patients and caregiver burden to improve cancer-related pain and caregiver burden.
MJO simulation in a cloud‐system‐resolving global ocean‐atmosphere coupled model

An observed Madden‐Julian Oscillation (MJO) propagating from the central Indian Ocean to the western Pacific from 15 December 2006 to 10 January 2007 was successfully simulated by a cloud‐system‐resolving global ocean‐atmosphere coupled model without parameterization of cumulus convection. We found that the ocean coupling has significant impacts on the MJO simulation, e.g., strength of the moisture convergence, and the timing and strength of the westerly wind burst over the Maritime Continent. The model also generally well simulated the decay of the MJO in the western Pacific, as well as the changes in sea surface temperature. These results demonstrate that the cloud‐system‐resolving global ocean‐atmosphere coupled model can be used for realistic MJO simulation.
ANALISIS KEBIJAKAN PENATAAN RUANG DAN DUKUNGAN PARTISIPASI MASYARAKAT TERHADAP KELESTARIAN LINGKUNGAN (Suatu Studi Kasus di Kota Bekasi)

The research is purpose to find out implementation spatial planning policies on Bekasi city for stainable environmental management? Analytical methods used are: 1) Geo-physics analysis of land suitability analysis, 2) physical analysis; 3) Analysis of environmental management, 4) Analysis of socio-economic conditions, and 5) Analysis Geographic Information System (GIS). The results obtained that spatial planning and environmental carrying capacity can be concluded that to meet the needs of diverse development needs to develop a spatial pattern of land use, coordinate, procedures for water and other resources in a unified a dynamic environment. To meet the needs of diverse development needs to develop a spatial pattern coordinate system guana land, procedures for water and other resources in a unified order dynamic environment. For that layout needs to be managed by an integrated pattern through a regional approach with respect to site natural environment, socio-cultural environment, and the artificial environment in accordance with its development. Good city spatial structure with more increased public participation in city layout is expected to be better. The parties involved in these activities the city department of administration, the whole society. There is a direct influence on the city hall community participation in maintaining a healthy environment, so if you want to increase public participation in maintaining a healthy environment can be done by increasing the city spatial planning. Knowledge to community environmental management in maintaining a healthy environment, can be done by improving environmental management Knowledge community. The implementation of spatial management that take by the government in accordance with the spatial planning and its implementation has been set well and need to optimize. In the spatial implementation among others include: planning the provision and utilization of green open space, and plan the provision and utilization of network infrastructure and pedestrian facilities. Keywords: Analisys of Wisdom, lay out, participation society
Legumes: A Vehicle for Transition to Sustainability

Legumes are an excellent source of protein and have been used in the human diet for centuries. Consumption of legumes has been linked to several health benefits, including a lower risk of cardiovascular diseases, type 2 diabetes mellitus, and certain types of cancer, while legumes’ high fiber content promotes digestive health. Aside from the positive health benefits, one of the most significant advantages of legumes is the low environmental footprint of their cultivation. They can be grown in a variety of climates and soil types, and they require less water and fertilizer than other crops, making them a sustainable option for farmers. Thanks to their nutritional and physicochemical properties, they are widely used by the food industry since the growing popularity of plant-based diets and the increasing demand for alternatives to meat offers the opportunity to develop legume-based meat substitutes. As the use of legumes as a source of protein becomes widespread, new market opportunities could be created for farmers and food industries, while the reduction in healthcare costs could have a potential economic impact. Achieving widespread adoption of legumes as a sustainable source of protein requires coordinated efforts by individuals, governments, and the private sector. The objective of this narrative review is to present the benefits coming from legume consumption in terms of health and environmental sustainability, and underline the importance of promoting their inclusion in the daily dietary pattern as well as their use as functional ingredients and plant-based alternatives to animal products.
The Role of Banks in Income Disparity Reduction in Indonesia: Islamic vs. Conventional Banks

This study aims to analyze the effect of Islamic and conventional banking in reducing income disparity in Indonesia. Based on the test using ARDL model, this study found two primary results. First, variables in Islamic banking such as total financing and third-party funds significantly reduce income disparity both in the long run and short run, while variables such as non-performing financing, and return on assets, contribute in the short run only. Second, variables in conventional banking such as total credit, non-performing loans, and third-party funds have a significant long-run impact on income disparity reduction, whereas all conventional banking variables significantly reduce income disparity in short run. The study's results have profound implications. Islamic banking institutions should strategically utilize their core principles to promote inclusion and effectively respond to the evolving requirements of society. Conventional banking institutions have the capacity to include socially responsible activities in order to achieve equitable outcomes. Finally, policymakers should foster a diverse financial sector, supporting Islamic banking growth and encouraging conventional banks to prioritize fairness. This approach aligns with Indonesia's socio-economic goals for a balanced financial landscape.
Epithelial cell moulds preserved in the earliest acrotretid brachiopods from the Cambrian (Series 2) of the Three Gorges area, China

Abstract Distinctive moulds of epithelial cells are known to occur on valve interiors in early Palaeozoic acrotretid brachiopods but morphological variation and distributional patterns of the epithelial cells imprints remains poorly known. Herein, we present for the first time a detailed study of exquisitely preserved epithelial cell moulds and shell micro-structures in acid-etched material of the earliest acrotretid brachiopod Eohadrotreta zhenbaensis from the Shuijingtuo Formation (Cambrian Series 2) of Aijiahe section, approximately 25 km north-west of Yichang City, western Hubei Province. The ventral and dorsal epithelial cell moulds (on average 18 μm across) are usually isometrically convex or concave polygonal with a variable outline (tetragon, pentagon and hexagon). Investigation of the new material demonstrates that the disposition of pronounced epithelial cell pustules or depressions in shell interiors most likely is associated with regions of thickened muscle attachments in ventral and dorsal valves – a character that potentially could be of use in taxonomy, though detailed comparative studies of such epithelial microstructures of acrotretids and other brachiopod taxa remain to be done.
Lumbar epidural analgesia and sciatic and femoral peripheral nerve blocks attenuate the stress-induced response in patients during the early postoperative period following total knee replacement

Invasive surgical procedures cause immune system downregulation by inducing a profound proinflammatory response. Establishing the most effective type of postoperative analgesia is crucial to maintain the equilibrium of the immune system. The purpose of this research was to evaluate the influence of epidural analgesia, peripheral nerve blockade as well as systemic analgesia on stress response in patients during the early postoperative period following total knee replacement. In total, 60 patients undergoing total knee replacement were allocated into three groups (n = 20, per group) in this prospective randomized study. Group 1, Group 2 and Group 3 received epidural analgesia, sciatic and femoral peripheral nerve blocks and systemic analgesia, respectively. Intensity of pain was measured at rest and upon movement. Blood samples were collected at baseline (T0), immediately before (T1) and after (T2) surgery, and 24 (T3) and 72 (T4) h postoperatively. The absolute number of leukocytes, concentrations of catecholamine, cortisol and C-reactive protein were determined. Patients in Group 1 and Group 2 exhibited lower pain scores than Group 3. Concentrations of cortisol and norepinephrine, but not epinephrine, were significantly lower in Group 1 and Group 2 at T2 than in Group 3. Significantly lower interleukin-1β concentrations were observed in Group 1 and Group 2 at T3 and T4 than in Group 3. Interleukin-6 concentrations were minor in Group 1 and Group 2 at T2 than in Group 3. Lumbar epidural analgesia and sciatic and femoral peripheral nerve blocks are effective analgesic techniques that reduce the acute inflammatory stress response in patients during the early postoperative period following total knee replacement.
Media, Politics, and Government Responsiveness: Evidence from Cyclone Relief in Madagascar

An important role of governments is to assist local populations in the wake of unexpected shocks. In this paper, we use evidence from cyclone relief in Madagascar to analyze the extent to which economic, media, and political variables determine government responsiveness. In particular, we compare government and non-government relief after cyclone Gafilo hit Madagascar in March 2004. We find that the probability of both types of assistance was higher in areas with a higher need for assistance. But, government responsiveness was also affected by media and political factors. Radio access increased the likelihood of receiving government relief, especially in more remote areas. The probability of receiving government relief was also higher in cyclone-affected communes with stronger political support for the government.