Miracle-dz/UniFAR-FTUs huggingface dataset:
Seismic torsional response and design procedures for a class of setback frame buildings

This paper presents results of an analytical study of the inelastic earthquake torsional response of a class of setback frame buildings. In the first part of the study, the modal response spectrum analysis procedure is utilized to determine the yielding strengths of structural members in an idealized but representative setback frame building model. Results are then presented for the inelastic dynamic response of this setback building model subjected to an ensemble of six earthquake ground motions. The results indicate that the modal response spectrum analysis procedure is inadequate for preventing excessive response leading to concentration of damage in vulnerable structural members, such as those in the tower near the notch and those in the base (the part of the structure below the tower) near the perimeter at the opposite side of the tower. The second part of the study develops a modified equivalent static force procedure for strength design of such setback frame buildings. Response analyses show that the proposed procedure results in improved and satisfactory inelastic performance of the selected class of setback frame buildings, having a wide range of realistic configurations.
The Diagnosis of COVID-19 through X-ray Images via Transfer Learning and Fine-Tuned Dense Layer on Pipeline

X-ray is used in medical treatment as a method to diagnose the human body internally from diseases. Nevertheless, the development in machine learning technologies for pattern recognition have allowed machine learning of diagnosing diseases from chest X-ray images. One such diseases that are able to be detected by using X-ray is the COVID-19 coronavirus. This research investigates the diagnosis of COVID-19 through X-ray images by using transfer learning and fine-tuning of the fully connected layer. Next, hyperparameters such as dropout, p, number of neurons, and activation functions are investigated on which combinations of these hyperparameters will yield the highest classification accuracy model. InceptionV3 which is one of the common neural network is used for feature extraction from chest X-ray images. Subsequently, the loss and accuracy graphs are used to find the pipeline which performs the best in classification task. The findings in this research will open new possibilities in screening method for COVID-19.
A physical, yet simple, small-signal equivalent circuit for the heterojunction bipolar transistor

A physical, yet simple, small-signal equivalent circuit for the heterojunction bipolar transistor (HBT) is proposed. This circuit was established by analyzing in detail the physical operation of the HBT. The model verification was carried out by comparison of the measured and simulated S- and Z-parameters for both passive (reverse-biased) and active bias conditions. A feature of this model is that it uses a direct extraction method to determine the parasitic elements, in particular, the parasitic capacitances. The excellent agreement between the measured and simulated parameters was verified all over the frequency range from 0.25 to 75 GHz.
Electromagnetic field and transmission characteristics of a parallel two-wire line covered with a three-layer media

Electromagnetic field and transmission characteristics of a parallel two-wire line (PTWL) covered with a three-layer media were analyzed. It becomes clear that the PTWL mode will strongly couple to the natural HE/sub 1m/ or EH/sub 1m/ modes. At the resonance frequencies, most of the electromagnetic energy is stored in medium II region, while propagation takes place in both medium II and III. Off resonance, most of the energy is concentrated close to the PTWL. Numerical results are in good agreement with experimental results. Such a line could possibly be used as a dielectric tube antenna or, alternatively, as a band elimination filter and so on. >
Interference cancellation schemes for a dual-rate variable processing gain DS/CDMA system

The existing multi-stage interference cancellation (IC) schemes have been extended to be specialized for the dual-rate DS/CDMA system with variable processing gains subject to the graded power control. The bit error rate performance using these IC schemes for the dual-rate DS/CDMA system is analytically derived under a frequency non-selective fading channel. Numerical examples in this analysis demonstrate that the rate-dependent near-far effect can be effectively eliminated with the proposed approaches under unfavorable situation of the graded power control, which incurs additional interference in the variable processing gain DS/CDMA system.
Impacts of Reduced Tire Pressure on Strain Response of Thaw-Weakened, Low-Volume Roads in Manitoba, Canada

The spring thaw period significantly reduces the bearing capacity of low-volume asphalt roads. To compensate for the reduced bearing capacity, highway agencies apply spring load restrictions (SLR) to limit the damage caused by heavy loads during the period when the road is weakened by thaw. Although the imposition of SLR may reduce road damage, it has a major impact on truck productivity. An alternative to reducing truck loads during the spring is the reduction of truck tire pressure. The reduced tire pressure lowers the tire–pavement contact pressure and the associated damage during the spring period. In 2008, asphalt strain gauges were installed in a section of a low-volume haul road in Manitoba, Canada. Field testing was conducted in the spring and fall of 2009 with a double semitrailer or B-Train equipped with a semiautomated tire pressure control system. The tests were conducted at various loads and speeds and at normal and reduced tire pressures. The results of the field testing showed that when the tire pressure was reduced by 50%, the measured maximum tensile strain at the bottom of the asphalt layer decreased by an average of 15% to 20%. The effects of gauge orientation, truck speed, and tire offset from the strain gauge were analyzed and are presented.
The Role of Digital Consumer Protection in Mediating the Effect of Mobile Money usage towards Financial Inclusion: an Evidence from Buleleng, Indonesia

The current utilization of digital services especially in finance sector among the productive age communities is increasing. Mobile money utilization and the implementation of a digitalization system in the financial sector are expected to increase financial inclusion. By increasing financial inclusion, the poverty rate is also expected to be reduced. Buleleng Regency is one of regency in Bali Province, Indonesia which has a high poverty rate. It is necessary to increase financial inclusion through mobile money usage. However, it is also necessary to increase consumer protection to support this digitalization. This research aims to determine the effect of mobile money usage on financial inclusion with digital consumer protection as a mediator in productive age communities in Buleleng Regency, Bali, Indonesia. The population of this research consists of 439,400 people from productive age group in Buleleng Regency, Bali, Indonesia. This research used a non-probability sampling technique with the total of 477 samples. This research applies the Sobel test, Baron and Kenny’s mediation analysis, and the PROCESS method by Hayes. The results of this study show that digital consumer protection partially mediates the effect of the mobile money usage on financial inclusion in Buleleng Regency, Bali, Indonesia. Based on the results of this study, it is suggested to regulators and related agencies in Indonesia to show more attention about the safety factors of mobile money users by strengthening consumer protection in terms of both regulation and the system reliability. Furthermore, it is also necessary to develop education programs on how to manage finance properly by using mobile money in order to improve people’s welfare.
Internal audit stigma impairs internal audit outcomes

Prior research finds that the internal audit function (IAF) plays a critical role in organizations, yet there is still a stigma toward the profession. We examine how this stigma affects internal audit outcomes, using three different data sources: survey results from parts of Europe (113 observations) and the United States (124 observations) for the year 2017 and an experiment (65 observations) in 2018. We find that when internal auditors in parts of Europe and the U.S. believe there is a negative stigma about internal auditing, they report negative work outcomes, including less ability to add value, less influence in the organization, more resistance to implementing their recommendations, and more pressure to change audit findings. Our experimental results confirm the survey findings and provide further evidence that negative stigma causes participants to perceive less value in internal audit reports and that internal audit recommendations are less influential in decision-making. Taken together, the results suggest that negative perceptions of internal audit have a significant impact on the profession
SUBSYNCHRONOUSRESONANCEZONES INTHEIEEE'BENCHMARK"POWERSYSTEM

Studies ofsubsynchronous resonance(SSR)phenomena are conducted ina powersystem composed ofaturbo-generator setconnected to an infinite busviaseries capacitor-compensated transmission lines. The analysis isapplied toa "benchmark"modelproposed bythespecial IEEEPowerEngineering Society TaskForceon Subsynchronous Resonance. Complete detailed representation oftheelectromechanical system hasconfirmed theexistence of(n-1) modes, wheren isthenumberof lumped massesoftheshaft, aswell astheexistence ofsuper-andsubsynchronous components intheelectrical network. Theeigenvalue method ofanalysis isusedtostudy theinteraction between mechanical andelectrical network dynamic behaviors undersmallperturbations, andtoidentify thevarious conditions inwhichthesystem wouldbe subjected totorsional interaction, induction generator effect, andhunting.
Inflammation-related microRNAs are involved in stressful life events exposure and in trauma-focused psychotherapy in treatment-resistant depressed patients

ABSTRACT Background: About 30% of major depressive disorder (MDD) patients are classified as resistant to treatment (treatment-resistant depression, TRD). Among the factors associated with unfavourable treatment outcomes, stressful life events play a relevant role, and trauma-focused psychotherapy has been successfully proposed for the treatment of patients with a history of such events. Stressful experiences are related to enhanced inflammation and, recently, microRNAs (miRNAs) have emerged as potential mediators of the association between these experiences and psychiatric disorders. To date, no study has explored the effects of stressful life events on miRNAs in MDD patients. Objective: The objective of the present study was to assess possible miRNA blood expression alterations in TRD patients induced by the exposure to stressful life events and to investigate the effects of trauma-focused psychotherapy on the expression profiles of the same miRNAs, as well as their possible predictivity in relation to therapy outcome. Method: The basal levels (T0) of seven candidate miRNAs (miR-15a/miR-29a/miR-125b/miR-126/miR-146a/miR-195/let-7f) were measured in the whole blood of 41 TRD patients. A subgroup of patients (n = 21) underwent trauma-focused psychotherapy; for all of them, miRNA levels were also longitudinally assessed (T4: after 4 weeks of treatment; T8: end of treatment; T12: follow-up visit), contextually to clinical evaluations. Results: miR-146a levels negatively correlated with recent stressful life event scores (p = .001), whereas the levels of miR-15a, miR-29a, miR-126, miR-195, and let-7f changed during the psychotherapy (best p = 1.98*10−9). miR-29a was also identified as a response predictor, with lower baseline levels predicting non-response (p = .019) or worse improvement in mood symptoms (p = .032). Conclusions: The study results could contribute to clarify the underlying molecular mechanisms and to identify novel biomarkers of stressful experiences and response to targeted treatments. HIGHLIGHTS The peripheral levels of microRNAs implicated in inflammation are correlated to recent stressful life events in treatment-resistant depressed patients and modified by trauma-focused psychotherapy; some of them could represent predictive biomarkers of response to psychotherapy.
Tissue-wide genetic and cellular landscape shapes the execution of sequential PRC2 functions in neural stem cell lineage progression

The generation of a correctly-sized cerebral cortex with all-embracing neuronal and glial cell-type diversity critically depends on faithful radial glial progenitor (RGP) cell proliferation/differentiation programs. Temporal RGP lineage progression is regulated by Polycomb Repressive Complex 2 (PRC2) and loss of PRC2 activity results in severe neurogenesis defects and microcephaly. How PRC2-dependent gene expression instructs RGP lineage progression is unknown. Here we utilize Mosaic Analysis with Double Markers (MADM)-based single cell technology and demonstrate that PRC2 is not cell-autonomously required in neurogenic RGPs but rather acts at the global tissue-wide level. Conversely, cortical astrocyte production and maturation is cell-autonomously controlled by PRC2-dependent transcriptional regulation. We thus reveal highly distinct and sequential PRC2 functions in RGP lineage progression that are dependent on complex interplays between intrinsic and tissue-wide properties. In a broader context our results imply a critical role for the genetic and cellular niche environment in neural stem cell behavior.
Who's in the Driver's Seat? Exploring Firm-Level vs. CEO-Level Effects on Problemistic Search

The Behavioral Theory of the Firm suggests that performance below an aspiration triggers problemistic search that can lead to organizational change and risk-taking. This compelling perspective has spawned considerable empirical examination of diverse strategic outcomes as firms’ responses to performance feedback. However, empirical studies have provided inconsistent evidence of problemistic search effects on various organizational search outcomes. This empirical controversy is likely attributed to the fact that most research has considered problemistic search as a firm-level and relatively routinized process with a high degree of automaticity in firms’ responses to performance feedback while overlooking the role of managerial agency. Rather than viewing problemistic search as an automatic firm-level process, we believe that behavioral responses are shaped, at least partially, by top executives, notably CEOs. To this end, we first examine whether problemistic search effects vary across a range of organizational change and risk outcomes. We then explore whether the relative size of firm and CEO effects varies across different search outcomes. Using a multilevel approach, we show not only the heterogeneity in problemistic search effects on different organizational outcomes but also heterogeneity in the relative size of firm and CEO effects on these outcomes. While firm effects are substantial in directing some strategic decisions, as proposed by the problemistic search model, CEO effects are large for certain organizational outcomes, such as changes in resource allocation. This study serves as a jumping-off point for future theorizing and empirical work on problemistic search that incorporate the role of managerial agency.
Comparison between solar radiation models based on cloud information

Simple radiation estimation models using few input parameters are often used in the applications requiring rough estimations of solar horizontal radiation. Cloud cover information is widely available for multiple regional and national weather stations. Kasten and Czeplak (1980) as well as Lam and Li (1998) have proposed cloud-based models for the estimation of global and diffuse horizontal irradiation. Muneer and Gul (2000) have analyzed solar radiation estimation models based on meteorological data and modified the Kasten–Czeplak's models to allow for local coefficients to be used. In this study, the Lam–Li model has been modified to allow for local coefficients, and three new models, which are primarily based on modifications to the Kasten–Czeplak model, have been proposed. To compare the validity of the above models, statistical indicators have been presently developed for assessing the accuracy of estimation of both global and diffuse irradiation. The slope of the best-fit line and the coefficient of determination between I G, measured; and I G, calculated; and I D, measured; and I D, calculated;, the percentage error, mean bias error and root mean square error for both global and diffuse horizontal irradiation were calculated. In addition, the kurtosis and skewness of error histograms were also obtained. These parameters were used to obtain the statistical indicators for the models under validation. It was concluded that although the proposed models outperformed the original Kasten–Czeplak and Lam–Li models, they performed on a par with the simpler Kasten–Czeplak model with modified local coefficients.
Stock assessment of the Indian scad, Decapterus russelli (Ruppell, 1830) from Mumbai waters

Present study consists the Growth, mortality and the stock assessment of Decapterus russelli . ‘L �’ was estimated as 277 mm and ‘K’ as 1.237/year. The t o estimated by VBGF plot was – 0.3443 year. Growth in length of D. russelli described following von Bertalanffy growth equation as, L t = 277[ 1-e -1.237{t-(-0.3443)} ]. Longevity was estimated to be 2.42 years. Total mortality rate (Z), natural mortality rate (M) and fishing mortality (F) were estimated to be 6.66, 2.1 and 4.56 respectively. In this study, Z/K was found to be 5.38 indicating that the stock of D. russelli is presently mortality dominated in Mumbai waters. Exploitation rate (U) was calculated as 0.6838 and the Exploitation ratio (F/Z) as 0.6847. Thompson and Bell longterm prediction analysis indicated that there is no decline in yield of D. russelli even if the fishing effort is doubled. Present level of fishing has no deleterious effect on the fishery of D. russelli
Plasma Endoglin is Associated with Favorable Outcome for Pemetrexed-Based Therapy in Advanced Non-Small Cell Lung Cancer

Purpose Pemetrexed-based chemotherapy (Pem-C) is the first-line chemotherapy for advanced non-squamous non-small cell lung cancer (NSCLC). However, limited tumor-associated proteins in blood are available to predict pemetrexed response and/or survival. Patients and Methods Plasma samples from three responders and three nonresponders with stage IIIB–IV NSCLC were collected prior to Pem-C and analyzed using Proteome ProfilerTM Human XL Oncology Array to detect 84 oncology-related proteins. The plasma concentrations of cathepsin S, endoglin (ENG), and matrix metalloproteinases 3 and 9 in 71 patients with advanced NSCLC treated with Pem-C were further measured using enzyme-linked immunosorbent assay based on the remarkable differences in the four proteins between responders and nonresponders in the array results. Results Pem-C responders had significantly higher ENG levels but not the other three markers than nonresponders (mean ENG level: 27.1 ± 7.4 vs 22.3 ± 6.9, p < 0.01). High ENG concentration was correlated with improved progression-free survival (hazard ratio [HR]: 0.52, 95% confidence interval [CI]: 0.31–0.86, p < 0.01) and overall survival (HR: 0.55, 95% CI: 0.32–0.94, p < 0.05) in patients treated with Pem-C, and the ENG level was an independent factor in our cohort (HR: 0.54, 95% CI: 0.33–0.89, p < 0.05). ENG concentration in Pem-C responders also significantly increased at the time of best response (p < 0.05). Conclusion Cumulatively, this study reveals that ENG is correlated with Pem-C responsiveness in patients, which indicates the potential use of plasma ENG levels as a non-invasive biomarker for pemetrexed-based treatment in patients with non-squamous NSCLC.
Analysis of message extraction in optical chaos communications based on injection-locking synchronization of semiconductor lasers

In this paper, we employ a simple theory based on driven damped oscillators to clarify the physical basis for message extraction in optical chaos communications using injection-locked semiconductor lasers. The receiver laser is optically driven by injection from the transmitter laser. We have numerically investigated the response characteristics of the receiver when it is driven by periodic (message) and chaotic (carrier) signals. It is thereby revealed that the response of the receiver laser in the two cases is quite different. For the periodic drive, the receiver exhibits a response depending on the signal frequency, while the chaotic drive provides a frequency-independent synchronous response to the receiver laser. CPF can be clearly understood in the difference between the periodic and chaotic drives. Message extraction using CPF is also examined, and the validity of our theoretical explanation for the physical mechanism underlying CPF is thus verified.
Aromatherapy for Symptom Relief in Patients with Burn: A Systematic Review and Meta-Analysis

Background and Objectives: This review aimed to provide an updated review of evidence regarding the effects of aromatherapy in relieving symptoms of burn injuries, focusing on pain and physiological distress. Materials and Methods: Fifteen databases (including five English databases, four Korean medical databases, and four Iranian databases) and trial registries were searched for studies published between their dates of inception and July 2021. Two review authors individually performed study selection, data extraction, and risk of bias assessment, and any discrepancies were solved by a third review author. Results: Eight RCTs met our inclusion criteria and were analyzed in this updated systematic review. Our meta-analyses revealed that inhaled aromatherapy plus routine care showed beneficial effects in relieving pain after dressing, as compared to placebo plus routine care (p < 0.00001) and routine care alone (p = 0.02). Additionally, inhaled aromatherapy plus routine care (p < 0.00001) and aromatherapy massage plus routine care (p < 0.0001) also showed superior effects in calming anxiety, as compared to routine care alone. None of the included studies reported on AEs. Overall, the risk of bias across the studies was concerning. Conclusions: This updated review and synthesis of the studies had brought a more detailed understanding of the potential application of aromatherapy for easing the pain and anxiety of burn patients.
Application of Electrospun Nanofiber Membrane in the Treatment of Diabetic Wounds

Diabetic wounds are complications of diabetes which are caused by skin dystrophy because of local ischemia and hypoxia. Diabetes causes wounds in a pathological state of inflammation, resulting in delayed wound healing. The structure of electrospun nanofibers is similar to that of the extracellular matrix (ECM), which is conducive to the attachment, growth, and migration of fibroblasts, thus favoring the formation of new skin tissue at the wound. The composition and size of electrospun nanofiber membranes can be easily adjusted, and the controlled release of loaded drugs can be realized by regulating the fiber structure. The porous structure of the fiber membrane is beneficial to gas exchange and exudate absorption at the wound, and the fiber surface can be easily modified to give it function. Electrospun fibers can be used as wound dressing and have great application potential in the treatment of diabetic wounds. In this study, the applications of polymer electrospun fibers, nanoparticle-loaded electrospun fibers, drug-loaded electrospun fibers, and cell-loaded electrospun fibers, in the treatment of diabetic wounds were reviewed, and provide new ideas for the effective treatment of diabetic wounds.