Miracle-dz/UniFAR-FTUs huggingface dataset:
The Larva and distribution of Psychomyia klapaleki Ma licky, 1995 (Trichoptera: Psychomyiidae)

According to Malicky (1995), genus Metalype Klapalek, 1898 is a synonym to Psychomyia Latreille, 1829 and, based on priority, the latter genus designation has to be used for Metalype fragilis Pictet, 1834, too. Therefore, together with the newly described Psychomyia klapaleki (Malicky, 1995) and the well-known Psychomyia pusilla Fabricius, 1781, there are now three Central-European Psy­ chomyia species. P. pusilla and P. fragilis are included in the larval keys of Edington & Hildrew (1995) and Waringer and Graf (1997, 2000), whereas P. kla­ paleki has been unknown so far. Recently, larvae and pupae of a Psychomyia species morphologically close to P. fragilis were collected from Zerovniscica, Zerovnica, Slovenia, which could be clearly associated with P. klapaleki by adults originating from the same location.
A study of knowledge, attitude and practice of corticosteroid use among prescribers in a tertiary care centre in Maharashtra

1 Associate Professor, Dept. of Pharmacology, Dr. V M Govt Medical College, Solapur 2 Assistant Professor, Dept. of Pharmacology, Govt. Medical College, Miraj *Corresponding Author Shagupta A Naikwadi AddressDept. of Pharmacology, Govt. medical college Miraj, Maharashtra. India 416410 Email: shagupta_06@yahoo.com, Phone No.9766871372 Abstract Introduction: Corticosteroids therapy is always associated with multiple drug interactions, adverse effects and super infections. Over the years, corticosteroids are apparently being abused by doctors and patients alike. With the increasing number of corticosteroids available for clinicians, there is need to understand the physician’s knowledge, attitude, and practice of corticosteroid use. Aim and Objectives: To study knowledge, attitude and practice among the practitioners towards the corticosteroid use. Methods: This prospective, observational, cross-sectional study was carried out over a period of three months among the resident doctors at a tertiary care hospital. Resident doctors from the clinical departments who commonly prescribe corticosteroids in the hospital were included in the study. Results: Total 70 residents completed the questionnaire. While prescribing the corticosteroids, 88.57% resident doctors gave instruction to their patients to avoid possible adverse effects and drug interactions. Though 94.28% doctors were aware about the different potencies of corticosteroids, only 34.28% were able to arrange them in descending order of their potency. 52.85% doctors were practicing alternate day therapy but only 38.57% were able to justify the alternate day therapy. 31.42% doctors use internet as a source of information while 37.14% refer books while 20% consult senior professional. Discussion and Conclusion: Corticosteroid is a doubleedged weapon. While getting maximum benefits and minimum adverse effects, doctors should be aware of their adverse effects, precautions, duration of treatment. Resident doctors are the first contact physician. Very few resident doctors have detail knowledge about the different potencies, adverse effects, measures to avoid these adverse effects. And there is a need to educate doctors about rational prescribing of corticosteroids.
Genotype Dependent Interspecific Hybridization of Sorghum bicolor

Wild Australian Sorghum species are a tertiary gene pool to grain sorghum [Sorghum bicolor (L.) Moench], and they are of interest to breeders because of their resistance to important insects and pathogens. However, strong reproductive barriers have prevented hybridization between S. bicolor and these wild species. The purpose of this study was to determine if the recessive iap allele (dominant allele Iap 5 inhibition of alien pollen) would reduce or eliminate the pollen–pistil incompatibilities that prevent hybridization between S. bicolor and divergent Sorghum species. Cytoplasmic male-sterile S. bicolor plants, homozygous for the iap allele, were pollinated with three divergent Sorghum species, S. angustum Blake, S. nitidum (Vahl) Pers. , and S. macrospermum Garber. The pollen of these three wild species readily germinated and the pollen tubes grew to the base of the S. bicolor ovary within 2 h after pollination. Hybrid embryos were detected in the S. bicolor florets 13 to 20 d post-pollination. Sorghum bicolor 3 S. angustum and S. bicolor 3 S. nitidum hybrids were obtained using embryo rescue followed by in vitro culture techniques and hybrids between S. bicolor and S. macrospermum were obtained by simply germinating the hybrid seed. These hybrids were confirmed by their morphological and cytological traits. These findings clearly demonstrate that the recessive iap allele circumvents pollen–pistilincompatibilitiesinthegenusSorghumand permitshybrids to be made between S. bicolor and species of the tertiary gene pool.
Continuous Relation Between Left Ventricular Mass and Cardiovascular Risk in Essential Hypertension

Abstract—The detection of left ventricular (LV) hypertrophy on echocardiography is a powerful risk indicator in essential hypertension. However, the prognostic impact of LV mass values within the “normal” range and the shape of the relation between LV mass and prognosis remain unclear. Thus, 1925 white subjects with uncomplicated essential hypertension underwent off-therapy 24-hour blood pressure monitoring and M-mode echocardiography. During 4.0±2 years of follow-up, there were 181 major cardiovascular events (2.4/100 patient-years) and 49 deaths from all causes. In the 5 gender-specific quintiles of LV mass distribution (partition values: 92, 105, 120, and 138 g/m2 in men and 79, 91, 102, and 116 g/m2 in women), cardiovascular event rates were 0.8, 1.7, 2.2, 2.9, and 4.3 per 100 patient-years. After adjustment for several risk factors, including 24-hour ambulatory blood pressure, the relative risk (RR) of developing a cardiovascular event increased progressively from the first quintile (RR 1) to the sec.
Improving the collaboration between architects and energy consultants through design-integrated early BIM-tools

There is a lack of optimization of buildings towards energy performance in early design stages in practice. Interviews with architects and energy consultants showed that one reason is the inefficient communication between these two groups. This paper investigates how a design-integrated early-BIM tool can improve the relation between architects and energy consultants to support an optimization process in early design stages and facilitate issuing energy performance certificates. Two case studies show that the early-BIM tool provides meaningful results for the architects involved and can reduce the input time for energy consultants by 50%. Furthermore, the simple 3D model functions as boundary object between the two groups and supports the collaboration.
Assessment of Liver Enzymes in the Patients Infected with Plasmodium

Malaria is a mosquito born disease caused by protozoa belonging to family Plasmodium. According to the WHO, involvement of liver in Plasmodium falciparum is not an uncommon feature and presence of jaundice (bilirubin ≥ 3 mg/dl) is one of the signs of malaria. Involvement of liver in malaria is a common feature and may manifest as jaundice, hepatomegaly & elevated liver enzymes like aspartate & alanine transferase. Detection of malaria positive cases and correlation of all malaria positive cases with Liver Function Test (LFT). The study was performed on 100 malaria positive patients. Collection of blood sample was done by venipuncture under aseptic conditions in the EDTA vial for the diagnosis of malaria and in the plain vial to perform liver function test. Malaria was diagnosed by the microscopy of PBS. The LFT was performed using auto analyzer and Erba diagnostic kit, according to manufacturer instructions. Out of 100 malaria positive patients total 70 (70%) patients were found having liver function test deranged while rest 30 (30%) patients were having normal liver function test. 48 (48%) patients showed deranged level of Total bilirubin, 59 (59%) patients showed deranged level of deranged level of SGOT, 57 (57%) patients showed deranged level of SGPT while deranged level of ALP is showed by 34 (34%) patients. Liver dysfunction in malarial infection ranged from mild elevation of liver enzymes and serum bilirubin (≥ 3 mg/dl) to acute hepatitis. It indicates severe illness with high frequency of complications and mortality rates and P. falciparum malaria is more effective to cause hepatic dysfunction that P. vivax malaria.
Alpine vegetation type affects composition of nutritionally important C18 fatty acids in tissues of lambs from different breeds

A total of 110 lambs of the breeds Engadine Sheep and Valaisian Black Nose Sheep were fattened on one lowland and three different alpine pasture types. The experiment was conducted in two consecutive years and lasted for 9 weeks of grazing in each year. Immediately afterwards, the lambs were slaughtered. Perirenal adipose tissue and the Longissimus dorsi muscle were analysed for fatty acid composition. The lambs on the lowland pasture had the lowest proportions of linoleic and α-linolenic acid in the lipid fraction of these tissues. Additionally, there was a clear differentiation in these proportions when lambs grazed different alpine vegetation types. This was related to the content of phenolic compounds rather than the fatty acid contents of the swards, and an increasing phenolic level probably resulted in a higher ruminal protection of the native plant fatty acids. Intermediates of biohydrogenation (vaccenic acid and conjugated linoleic acid) were highest in the lowland lambs. Animal breed effects were weak.
Lightweight Bilateral Convolutional Neural Networks for Real-time Diffuse Global Illumination

—Physically correct, noise-free global illumination is crucial in physically-based rendering, but often takes a long time to compute. Recent approaches have exploited sparse sampling and ﬁltering to accelerate this process but still cannot achieve real-time performance. It is partly due to the time-consuming ray sampling even at 1 sample per pixel, and partly because of the complexity of deep neural networks. To address this problem, we propose a novel method to generate plausible global illumination for dynamic scenes in real-time ( > 30 FPS). In our method, we ﬁrst compute direct illumination and then use a lightweight neural network to predict screen space indirect illumination. Our neural network is designed explicitly with bilateral convolution layers and takes only essential information as input (direct illumination, surface normals, and 3D positions). Also, our network maintains the coherence between adjacent image frames efﬁciently without heavy recurrent connections. Compared to state-of-the-art works, our method produces global illumination of dynamic scenes with higher quality and better temporal coherence and runs at real-time framerates.
EFFECT OF FORTIFIED LOW FAT-SOFT CHEESE WITH ARABIC GUM ON PHYSICOCHEMICAL AND RHEOLOGICAL PROPERTIES

Arabic gum can be consider as alternative substance of fat, which can be improve the low fat cheese characteristics. Therefore, the current study aims to add Arabic gum as an alternative of fat in low-fat soft cheese with no effect on the functional properties of cheese. Arabic gum powder at 2, 4 and 6% was added into cheese before the pasteurization was done in 63C for 30 minutes. The samples of cheese were stored for (1 and 14) days at a temperature (1±5)C. Then, the proximate analysis were conducted such as moisture, ash, protein, compressibility and elasticity. The results of the sensory evaluation such as consist of flavor, color, consistency, holes and bitterness showed that the cheese fortified with Arabic gum at 4% had the highest levels in comparison with other samples. Thus, this study was indicated that the added of Arabic gum to low fat soft cheese up to 4% could improve the compressibility as well as the elasticity. The results presented that utilizing of Arabic gum could improve the functional and nutritional properties of low fat soft cheese.
Microstructural White Matter Abnormalities and Cognitive Functioning in Type 2 Diabetes

OBJECTIVE To examine whether type 2 diabetes is associated with microstructural abnormalities in specific cerebral white matter tracts and to relate these microstructural abnormalities to cognitive functioning. RESEARCH DESIGN AND METHODS Thirty-five nondemented older individuals with type 2 diabetes (mean age 71 ± 5 years) and 35 age-, sex-, and education-matched control subjects underwent a 3 Tesla diffusion-weighted MRI scan and a detailed cognitive assessment. Tractography was performed to reconstruct several white matter tracts. Diffusion tensor imaging measures, including fractional anisotropy (FA) and mean diffusivity (MD), were compared between groups and related to cognitive performance. RESULTS MD was significantly increased in all tracts in both hemispheres in patients compared with control subjects (P < 0.05), reflecting microstructural white matter abnormalities in the diabetes group. Increased MD was associated with slowing of information-processing speed and worse memory performance in the diabetes but not in the control group after adjustment for age, sex, and estimated IQ (group × MD interaction, all P < 0.05). These associations were independent of total white matter hyperintensity load and presence of cerebral infarcts. CONCLUSIONS Individuals with type 2 diabetes showed microstructural abnormalities in various white matter pathways. These abnormalities were related to worse cognitive functioning.
PD-L1 expression and tumor-infiltrating lymphocytes

Upon analysis of 636 primary breast carcinoma patient samples, we have found that programmed cell death ligand 1 (PD-L1) mRNA expression is associated with tumor-infiltrating lymphocytes (TILs). Furthermore, PD-L1 expression and elevated TILs were associated with longer recurrence-free survival. Thus, our findings indicate that PD-L1 is prognostic in breast cancer and suggests a functional link between TILs and tumor PD-L1 upregulation.
Effect of Obesity on the Levels of Salivary Matrix Metalloproteinase-8 (MMP-8) in Chronic Periodontitis Patients

Matrix metalloproteinase (MMP-8) is currently considered to be one of the most significant biomarkers for the development and early diagnosis of periodontitis. The aim of this study was to assess the salivary levels of MMP-8 in obese with chronic periodontitis patients. The study involved 60 subjects visiting the School of Dental Sciences, Universiti Sains Malaysia, Kota Bharu, Kelantan, Malaysia. The participants were divided into two groups: group I consisted of 30 non-obese subjects with periodontitis while group II consisted of 30 patients with obesity and periodontitis. Chronic periodontitis was evaluated by several periodontal parameters, such as periodontal pocket depth (PPD), clinical attachment level (CAL), gingival bleeding index, plaque score, and obesity were measured by Body Mass Index (BMI). 3ml of stimulated saliva was collected for assessment of MMP-8 by enzyme-linked immunosorbent assay kit. Data were statistically analyzed by the independent t-test. The salivary MMP-8 protein levels were slightly higher in group II as compared to group I, however, it was not statistically significant (P=0.06). Only PPD and CAL were found statistically significant (P<.001, P=.005) when compared between both groups. The findings of this study demonstrate no association between obesity and salivary MMP-8 levels in chronic periodontitis patients. Clinical article (J Int Dent Med Res 2020; 13(1): 315-320)
THE ROLE OF UNCERTAINTY, PERCEIVED EASE OF USE, AND PERCEIVED USEFULNESS TOWARDS THE TECHNOLOGY ADOPTION

This research integrated the concept of uncertainty and compatibility into Technology Acceptance Model (TAM). The context of technology adoption is analyzed from the craftsman’s side who is also the user. Most of the craftsmen in Micro Small Medium Enterprises (MSME) are elderly who are resistant to new technology. Main objective of this research is to test innovation adoption model on MSME which are affected by uncertainty, perceive usefulness, ease of use, and compatibility.
Spectral Rendering with Daylight: A Comparison of Two Spectral Daylight Simulation Platforms

Colours that surround us are not just the result of surface properties, rather the interplay between the spectral distribution of illuminating light and spectrally speciﬁc surface reﬂectance. Despite the temporal and spatial variation of daylight spectral distribution, daylight simulation platforms most commonly use luminance based sky models (CIE or all-weather Perez skies) that lack spectral and colorimetric information. LARK and ALFA are the two currently available spectral daylight simulation platforms that use spectral data of skies and materials to produce daylight renderings. The authors measure and perform visual, spectral and colour diﬀerence comparisons of complex urban scenes with diﬀerent materiality—plaster facades, vegetation, reﬂective facades—in LARK, ALFA and standard non-spectral daylight simulations. The comparisons present the challenges, applications and limitations of using the currently evolving multi-spectral daylight simulations.
Detectability of fluorescent gold nanoparticles under micro-CT and optical projection tomography imaging

Abstract. Purpose: Preclinical studies often compare micro-computed tomography (micro-CT) imaging with histology using optical microscopy of fluorescently labeled slides. However, correlating the images is difficult because the tissues appear differently in the two modalities. It would be valuable to have a single contrast medium visible on both radiographic and optical imaging. Approach: We have explored the detectability of fluorescently labeled gold nanoparticles under micro-CT and optical projection tomography (OPT) in agarose phantoms and a murine melanoma tumor model. Murine melanoma cells were used to induce tumor growth in the right hind legs of 12 C57Bl6 mice, with the maximal tumor size of 1 cm3. We injected Cy3 fluorescently coated gold nanorods directly into the tumors. The mice were scanned with in vivo micro-CT (for pre- and post-contrast scans). Once euthanized, the hind leg was dissected and scanned with a higher resolution specimen micro-CT and OPT. Results: The distribution of the gold nanoparticles appeared to be contained and isolated to the tumor. Alignment of micro-CT specimen scans with the OPT scans was possible, although there was also autofluorescence of the surrounding muscle tissue. Conclusions: This study highlights the potential use of fluorescently labeled gold nanoparticles for imaging murine melanoma tumors using micro-CT and OPT.
The Effect of Product Quality, Brand Image, Price, and Advertising on Purchase Decision and its Impact on Customer Loyalty of Morinaga Milk in Aceh

The lack of studies regarding purchase decisions about customer loyalty is the reason for the emergence of new concepts about the influence of product quality, brand image, price and advertising on purchase decisions that have implications for the loyalty of Morinaga milk customers in Aceh. This study uses quantitative analysis where the data analysis technique is the structural equation model, SEM Amos, and uses forty references related to product quality, brand image, price, advertising, decision making, and customer loyalty. It includes 250 respondents as the study samples. The results of the study reveal that product quality, brand image, price, and perceived advertisement have a significant effect on the purchase decision of customers and have an effect on customer loyalty. These results provide support for the concept of the relationship between decision making and customer loyalty and empirical evidence on the mediating effects of decision making on the relationship between marketing mix elements and customer loyalty.
Timed automata based analysis of embedded system architectures

We show that timed automata can be used to model and to analyze timeliness properties of embedded system architectures. Using a case study inspired by industrial practice, we present in detail how a suitable timed automata model is composed. Exact upper bounds on the timeliness properties can be found with the Uppaal model checker for a number of usage scenarios. We compare our results with three other performance modeling techniques. This comparison shows that if the state space of the model is tractable, Uppaal gives the most accurate results at similar cost. The proposed modeling strategy can be automated, which alleviates the difficulty and error-proneness of manually constructing timed automata models
Parametric Study of diﬀerent Levels of Detail of CityGML and Energy-ADE Information for Energy Performance Simulations

Information handling and decision making for energy analysis at urban level is often diﬃcult for simulation scientists. Often, a lack of the required Levels of Detail (LoD) of the information can be seen. Comparing the process of statistically enriching building archetypes for lower LoD to the usefulness of speciﬁc available information using the CityGML standard and Energy ADE for higher LoD, this paper will allow the users to make an eﬃcient choice over the de-sired LoD for reducing the deviations in heating load simulations between monitored values and computed results.
Isoflavone Changes During Fermentation of Kerandang (Canavalia virosa) Milk using Lactobacillus plantarum-pentosus and its Anticancer Activity

Kerandang (Canavalia virosa) seeds contain bioactive compounds such as isoflavone whose beneficial effects need to be explored. The intake of isoflavone genistein and daidzein has been shown to provide protection against reactive oxygen species, cardiovascular disease and cancer disease among other benefits. The objective of this research was to investigate the isoflavone changes during fermentation of Kerandang milk and to evaluate its anticancer activity on colon cancer 26 cells. Kerandang milk was fermented using L. plantarum-pentosus T14 and L. plantarum-pentosus T35 for 24 hr at 37 °C. The L. plantarum-pentosus T14 and L. plantarum-pentosus T35 growth rates, total lactic acid, pH and isoflavone content were analyzed. The viability of colon cancer 26 cells was assayed using the WST-8 method. The results indicated that a change occurred from isoflavone glucoside to isoflavone aglycone during fermentation using L. plantarum-pentosus T14 and L. plantarum-pentosus T35. The methanol extract of isoflavone from Kerandang milk fermented by L. plantarum-pentosus T14 and L. plantarumpentosus T35 had anti cancer activity as indicated by the decreased viability of colon cancer 26 cells. The methanol extract of isoflavones from Kerandang milk fermented using L. plantarum-pentosus T14 has greater anti cancer activity than the methanol extract of isoflavones from Kerandang milk fermented using L. plantarum-pentosus T35 and methanol extract of Kerandang milk. In conclusion, fermentation of kerandang milk with lactic acid bacteria can increase its functional value, such as anticancer activity.