Miracle-dz/UniFAR-FTUs huggingface dataset:
Modeling landfill gas potential and potential energy recovery from Thohoyandou landfill site, South Africa

ABSTRACT The increase in solid waste generation has been a major contributor to the amount of Greenhouse gases (GHGs) present in the atmosphere. To some extent, a great chunk of these GHGs in the atmosphere is from landfill. This study assesses two theoretical models (LandGEM and Afvalzorg models) to estimate the amount of landfill gas (LFG) emitted from Thohoyandou landfill site. Also, the LFGcost Web model was used to estimate the cost and benefits of the implementation of an LFG utilization technology. The Thohoyandou landfill started operations in the year 2005 and it is proposed to reach its peak at approximately in the year 2026. The LandGEM calculates the mass of landfill gas emission using methane generation capacity, mass of deposited waste, methane generation constant and methane generation rate. Meanwhile, the Afvalzorg model determines the LFG emissions using the Methane correction factor, yearly waste mass disposal, waste composition, Degradation Organic Carbon, methane generation rate constant, LFG recovery efficiency. The study findings indicate that the methane (CH4) and carbon dioxide (CO2) emitted from the landfill estimated from LandGEM will peak in the year 2026 with values of 3517 Mg/year and 9649 Mg/year, respectively. Results from the Afvalzorg model show that CH4 emission will peak in the year 2026 (3336 Mg/year). The LandGEM model showed that the total LFG, CH4 and CO2 emitted from the landfill between 2005 and 2040 are 293239.3 Mg/year, 78325.7 Mg/year and 214908.6 Mg/year, respectively. The simulation from the Afvalzorg model found that the CH4 emitted from the years 2005– 2040 is 74302 Mg/year. The implementation of an LFG utilization technology was economically feasible from consideration of the sales of electricity generated and Certified Emission Reductions (CER) (carbon credits). Implications The methane (CH4) and carbon dioxide (CO2) emitted from the Thohoyandou landfill estimated from LandGEM will peak in the year 2026 at 3517 Mg/year and 9649 Mg/year, respectively. The Afvalzorg model shows that CH4 emission will peak in the year 2026 (3336 Mg/year). The LandGEM model showed that total LFG, CH4 and CO2 emitted from the landfill between 2005 and 2040 (Mg/year) are 293,239, 78,325 and 214,908, respectively. The simulation from the Afvalzorg model found that CH4 emitted from years 2005– 2040 is 74,302 Mg/year. Therefore, implementation of LFG utilization is economically feasible from sales of electricity generated and Certified Emission Reductions.
Determination of Genetic Divergence Based on DNA Markers Amongst Monosporidial Strains Derived from Fungal Isolates of Karnal Bunt of Wheat

Genetic variation among the base isolates and monosporidial strains derived from these isolates of Tilletia indica- the causal agent of Karnal bunt (KB) in wheat, was analyzed by morphological, growth behaviors and RAPD-ISSR based molecular polymorphism. Genetic make up of fungal cultures vary among each other. The magnitude of variation in KBPN group is less (narrow genetic base) when compared to the other groups KB3, KB9 and JK (broad genetic base) reflecting that variability is a genetically governed process. The generation of new variation with different growth characteristics is not a generalized feature and is totally dependant on the original genetic make-up of the base isolate generating new monosporidial strains. Thus, it can be concluded that monosporidial strains derived from mono-teliosporic isolate, consists of genetically heterogeneous population. The morphological and genetic variability further suggests that the variation in T. indica strains is predominantly derived through the genetic rearrangements through para sexual means.
Diet composition of juveniles of rough ray Raja radula (Chondrichthyes: Rajidae) from the Ionian Sea

Abstract The diet of juvenile specimens of Raja radula from the Ionian Sea was investigated. The stomach contents of 43 specimens were analysed in order to evaluate composite index (IRI Index of Relative Importance). To assess feeding strategy and trophic niche width, prey-specific biomass plotted against frequency of occurrence and Levins index were used, respectively. The diet of juvenile specimens of R. radula consisted mainly of crustacean decapods followed by algae, polychaetes and molluscs. Among crustaceans, Liocarcinus spp. were the most important prey items, with four species with relatively high IRI values. Most specimens had been feeding on L. pusillus, L. depurator and polychaetes, but the variation of prey-specific biomass indicates that there is not a clear dominance of any prey and the value of niche width indicates a high variability in R. radula diet. Differences between sexes exists only in % IRI values related to Liocarcinus spp. The results indicate that R. radula feeds on a wide range of prey items, although crustaceans were the favoured food source.
Determining the steering direction in critical situations: A decision tree–based method

Abstract Objective: Factors related to the driver–vehicle–environment system have a significant influence on a driver’s decision to perform evasive maneuvers, especially the decision of steering direction (DSD) in critical situations. However, few studies have systematically investigated the relationships between these factors and DSD. The objective of this study is to analyze and model drivers’ DSD in critical situations. Methods: Data from the NASS-CDS from 1995 to 2015 were utilized in this study. The decision tree (DT) classifier was utilized to model a driver’s DSD for both intersection-related and non-intersection-related subsets, combined with a 10-fold cross-validation technique and grid search approach to evaluate and optimize the model. An analysis of variable importance was also conducted. Results: Two separate DT models of drivers’ DSD were obtained based on the optimized hyperparameters, with test accuracies of 84.6% (intersection-related) and 79.2% (non-intersection-related). The variable DIFFANGLE (angle difference between 2 vehicles) ranked as the most important factor influencing drivers’ DSD in both models. The variables, in order of importance, were SPEED (travel speed of the subject vehicle) and AGE (driver’s age) for the intersection-related model and SPEED, PREMOVE (pre-event movement), TRAFFLOW (trafficway flow), and AGE for the non-intersection-related model. Moreover, an interesting same direction pattern was observed in both DT models. Conclusions: This study employed NASS-CDS data and DT classifiers to analyze and model drivers’ DSD behavior. The test accuracies for both classifiers were acceptable. Potential variables influencing drivers’ DSD were explored, which improves the research on evasive behavior in lateral movement and promotes further applications for intelligent vehicles using the constructed models.
Contrasting spring and summer phytoplankton dynamics in the nearshore Southern California Bight

We analyzed a 9‐yr record of ocean color data from the Sea‐viewing Wide Field‐of‐view Sensor (SeaWiFS) together with a 4‐yr record of satellite‐derived sea surface temperature (SST) measurements to investigate potential mechanisms influencing nearshore phytoplankton variability in the Southern California Bight. We also compared in situ physicochemical conditions at four shoreline stations during a year with an extensive nearshore dinoflagellate red tide (2005) to those of the following year when there was no extended red tide (2006). SeaWiFS data indicated that in spring, chlorophyll a (Chl a) and nitrate (NO3−) were inversely correlated to SSTs, consistent with an upwelling‐dominated system, but in summer Chl a and NO3− were unrelated to SST. Summer dissolved inorganic nitrogen concentrations were not well correlated between alongshore sampling stations, but showed a significant effect of tide stage (low vs. high). Mean summer nearshore Chl a was positively, linearly related to rainfall in the previous winter. The relationship between summer Chl a and winter precipitation could be due either to direct freshwater inputs during the winter rainy season or to delayed input via groundwater discharge. A first‐order analysis of nutrient delivery from both surface runoff and groundwater discharge showed that they could sustain summer blooms of up to 7540 and 1700 km2, respectively—areas on the order of the study site. However, precipitation‐induced physical changes to the nearshore water column cannot be conclusively ruled out as a potential causative mechanism.
Reinforcement Sensitivity Theory of Personality Questionnaire: Factor Structure Based on CFA and ESEM, and Associations with ADHD

Abstract Revised reinforcement sensitivity theory (r-RST) of personality is a major neuropsychological theory of motivation, emotion and personality. This paper presents the results of a study examining: (1) the factor structure of the Reinforcement Sensitivity Theory of Personality Questionnaire (RST-PQ) using confirmatory factor analysis (CFA) and exploratory structural equation modeling (ESEM); and (2) the relationships of the r-RST constructs in the RST-PQ with attention deficit hyperactivity disorder (ADHD) symptom groups of inattention (IA) and hyperactivity/impulsivity (HI). A total of 572 (Sample 1) and 309 (Sample 2) adults completed the RST-PQ. Participants in Sample 2 also completed a questionnaire measuring ADHD symptoms. Results revealed more support for the ESEM model with six factors than the CFA model. For both the ESEM and CFA models, both IA and HI symptom groups were associated positively with the RST-PQ constructs of behavioral inhibition system (BIS) and behavioral approach system (BAS) Impulsivity, with IA also associated negatively with the BAS-Goal-Drive Persistence. The theoretical implications of these findings for understanding the factor structure of the RST-PQ, and for ADHD (IA and HI) in terms of r-RST, are discussed.
The influence of energetic state on the form of stabilimentum built by Octonoba sybotides (Araneae: Uloboridae)

The influence of food supply on the type of stabilimentum built by Octonoba sybotides, an uloborid spider, was investigated in a laboratory experiment. Spiders were separated into two groups that built distinct stabilimenta (linear or spiral), | and then further subdivided into two different feeding groups (food-deprived and food-supplemented). Food-deprived spiders (a fruit fly every 10 d) tended to form spiral stabilimenta, whereas food-supplemented spiders (a fruit fly every 2 d) tended to form linear stabilimenta. Furthermore, there was a significant difference in the distribution of stabilimentum forms before and after egg production. After egg production, which involves a large expenditure of energy, spiders tended to form spiral stabilimenta. Thcse results suggest that the spider's energetic state influences the type of stabilimentum built by O vbotides, and that hunger induces the spider to form spiral stabilimenta.
Cerebroarterial pulsatility and resistivity indices are associated with cognitive impairment and white matter hyperintensity in elderly subjects: A phase-contrast MRI study

Increased cerebroarterial pulsations are thought to be contributing factors in microvascular damage and cognitive impairment. In this study, we assessed the utility of two-dimensional (2D) phase-contrast MRI (PC-MRI) in quantifying cerebroarterial pulsations and evaluated the associations of pulsatile and non-pulsatile hemodynamic measures with cognitive performance and white matter hyperintensities (WMH). Neurocognitive assessments on 50 elderly subjects were performed using clinical dementia rating (CDR) and Montreal cognitive assessment (MoCA). An electrocardiogram-gated 2D PC-MRI sequence was used to calculate mean flow rate, pulsatility index (PI), and resistivity index (RI) of the internal carotid artery. For each subject, whole brain global cerebral blood flow (gCBF) and relative WMH volume were also quantified. Elevated RI was significantly associated with reduced cognitive performance quantified using MoCA (p = 0.04) and global CDR (p = 0.02). PI and RI were both significantly associated with relative WMH volume (p = 0.01, p < 0.01, respectively). However, non-pulsatile hemodynamic measures were not associated with cognitive impairment or relative WMH volume. This study showed that the cerebroarterial pulsatile measures obtained using PC-MRI have stronger association with the measures of cognitive impairment compared to global blood flow measurement and as such, might be useful as potential biomarkers of cerebrovascular dysfunction in preclinical populations.
Nano-Polyplexes Mediated Transfection of Runx2-shRNA Mitigates the Osteodifferentiation of Human Valvular Interstitial Cells

Calcific aortic valve disease (CAVD) is a progressive disorder that increases in prevalence with age. An important role in aortic valve calcification is played by valvular interstitial cells (VIC), that with age or in pathological conditions acquire an osteoblast-like phenotype that advances the disease. Therefore, pharmacological interventions aiming to stop or reverse the osteoblastic transition of VIC may represent a therapeutic option for CAVD. In this study, we aimed at developing a nanotherapeutic strategy able to prevent the phenotypic switch of human aortic VIC into osteoblast-like cells. We hypothesize that nanocarriers designed for silencing the Runt-related transcription factor 2 (Runx2) will stop the progress or reverse the osteodifferentiation of human VIC, induced by high glucose concentrations and pro-osteogenic factors. We report here the potential of fullerene (C60)-polyethyleneimine (PEI)/short hairpin (sh)RNA-Runx2 nano-polyplexes to efficiently down-regulate Runx2 mRNA and protein expression leading subsequently to a significant reduction in the expression of osteogenic proteins (i.e., ALP, BSP, OSP and BMP4) in osteoblast-committed VIC. The data suggest that the silencing of Runx2 could represent a novel strategy to impede the osteoblastic phenotypic shift of VIC and the ensuing progress of CAVD.
Admissions to Veterans Affairs Hospitals for Emergency Conditions During the COVID-19 Pandemic.

Author Contributions: Drs Degesys and Wang had full access to all of the data in the study and take responsibility for the integrity of the data and the accuracy of the data analysis. Concept and design: All authors. Acquisition, analysis, or interpretation of data: All authors. Drafting of the manuscript: Degesys, Wang, Kwan, Fahimi, Noble. Critical revision of the manuscript for important intellectual content: All authors. Statistical analysis: Wang, Fahimi. Administrative, technical, or material support: Degesys, Kwan, Noble. Supervision: Degesys, Wang, Noble, Raven.
Poor Time in Therapeutic Range Control is Associated with Adverse Clinical Outcomes in Patients with Non-Valvular Atrial Fibrillation: A Report from the Nationwide COOL-AF Registry

Background: Warfarin remains the most commonly used oral anticoagulant (OAC) in Thailand for stroke prevention among patients with non-valvular atrial fibrillation (NVAF). The aim of this study was to investigate the relationship between time in therapeutic range (TTR) after warfarin initiation and clinical outcomes of NVAF. Methods: TTR was calculated by the Rosendaal method from international normalized ratio (INR) data acquired from a nationwide NVAF registry in Thailand. Patients were followed-up every six months. The association between TTR and clinical outcomes was analyzed. Results: There was a total of 2233 patients from 27 hospitals. The average age was 68.4 ± 10.6 years. The average TTR was 53.56 ± 26.37%. Rates of ischemic stroke/TIA, major bleeding, ICH, and death were 1.33, 2.48, 0.76, and 3.3 per 100 person-years, respectively. When patients with a TTR < 65% were compared with those with TTR ≥ 65%, the adjusted hazard ratios (aHR) for the increased risks of ischemic stroke/TIA, major bleeding, ICH, and death were 3.07, 1.90, 2.34, and 2.11, respectively. Conclusion: Poor TTR control is associated with adverse clinical outcomes in patients with NVAF who were on warfarin. Efforts to ensure good TTR (≥65%) after initiation of warfarin are mandatory to minimize the risk of adverse clinical outcomes.
Effects of antidepressant medicines on preventing relapse of unipolar depression: a pooled analysis of parametric survival curves

Abstract Background Major depressive disorder is characterized by a high risk of relapse. We aimed to compare the prophylactic effects of different antidepressant medicines (ADMs). Methods PubMed, Cochrane Central Register of Controlled Trials, Embase and the Web of Science were searched on 4 July 2019. A pooled analysis of parametric survival curves was performed using a Bayesian framework. The main outcomes were hazard ratios (HRs), relapse-free survival and mean relapse-free months. Results Forty randomized controlled trials were included. The 1-year relapse-free survival for ADM (76%) was significantly better than that for placebo (56%). Most of the relapse difference (86.5%) occurred in the first 6 months. Most HRs were not constant over time. Proof of benefit after 6 months of follow-up was not established partially because of small differences between the drug and placebo after 6 months. Almost all studies used an ‘enriched’ randomized discontinuation design, which may explain the high relapse rates in the first 6 months after randomization. Conclusions The superiority of ADM v. placebo was mainly attributed to the difference in relapse rates that occurred in the first 6 months. Our analysis provided evidence that the prophylactic efficacy was not constant over time. A beneficial effect was observed, but the prevention of new episodes after 6 months was questionable. These findings may have implications for clinical practice.
Assessment of the Wearability of Facemasks against Air Pollution in Primary School-Aged Children in London

Air pollution is a major health problem and children are particularly vulnerable to the adverse effects. Facemasks are one form of protection but, to be effective, they need to filter out airborne pollutants, fit the face well and be wearable. In this pilot study, we assess the perceived wearability of three facemasks (Vogmask, TuHao and ReSpimask) marketed in the UK as being designed to protect children against exposure to air pollution. Twenty-four primary school children wore each facemask during a standardised walking and running activity. After each activity, the children were asked to rate facemask wearability in terms of parameters, such as perceived comfort, hotness, breathability and fit. At the end of the trial, the children compared and identified their preferred facemask. The main complaint about the facemasks was the children’s faces being too hot. The ReSpimask was most frequently reported as being perceived to be the hardest to breathe through. The TuHao facemask was the only adjustable strap mask assessed but was reported to be difficult to adjust. Facemasks with a nose clip were frequently rated highest for fit (TuHao and Vogmask). The patterned, cloth fabric Vogmask had significantly higher ratings for appearance and perceived fit. The results show children’s perceptions of facemasks are highly affected by the facemask’s design, hotness and perceived breathability. By making children’s facemasks more appealing, breathable, cooler and improving their fit, wearability may be improved.
Spatial Distribution of Zooplankton Diversity across Temporary Pools in a Semiarid Intermittent River

This study describes the richness and density of zooplankton across temporary pools in an intermittent river of semiarid Brazil and evaluates the partitioning of diversity across different spatial scales during the wet and dry periods. Given the highly patchy nature of these pools it is hypothesized that the diversity is not homogeneously distributed across different spatial scales but concentrated at lower levels. The plankton fauna was composed of 37 species. Of these 28 were Rotifera, 5 were Cladocera, and 4 were Copepoda (nauplii of Copepoda were also recorded). We showed that the zooplankton presents a spatially segregated pattern of species composition across river reaches and that at low spatial scales (among pools or different habitats within pools) the diversity of species is likely to be affected by temporal changes in physical and chemical characteristics. As a consequence of the drying of pool habitats, the spatial heterogeneity within the study river reaches has the potential to increase β diversity during the dry season by creating patchier assemblages. This spatial segregation in community composition and the patterns of partition of the diversity across the spatial scales leads to a higher total diversity in intermittent streams, compared to less variable environments.
Light and temperature demands of marine benthic microalgae and seaweeds in polar regions

Polar algae have a striking ability to photosynthesize and grow under very low light and temperatures. In seaweeds, minimum light demands for photosynthetic saturation and compensation can be as low as 10 and 2 mu mol photons m(-2) s(-1), respectively. For benthic microalgae, these values can be even lower because of the limited irradiance reaching deep sea floors. The extreme shade adaptation of these organisms sets their distributional limits at depths close to 40 m and enables them to tolerate long periods of extended darkness. In addition to their capability for efficient photosynthesis at extremely low light levels, polar algae possess metabolic adaptations to persist at low temperatures, which permit them to complete their life cycles at year-round temperatures close to 0 degrees C. Seaweeds with the lowest temperature demands are the species endemic to the Antarctic while Arctic algae are comparatively less cold-adapted. These adaptive characteristics allow benthic marine algae to make high contributions to high latitude coastal primary productivity and energy fluxes, exceeding or equaling the production of primary producers in more temperate systems. The studies summarized here give important insights into the major physiological adaptations allowing marine benthic microalgae and seaweeds to colonize these extreme habitats.
Conservation assessment of the critically endangered frog Mantella aurantiaca in Madagascar

Abstract Mantella aurantiaca is a small, bright orange, terrestrial amphibian that is endemic to the island of Madagascar. The species has attracted significant attention from herpetologists and captive breeders but relatively little effort has been given to its conservation in the wild. We surveyed 33 reported breeding localities of the species to determine sites of conservation importance and aspects of habitat use and seasonality. We found a total of 471 M. aurantiaca in 26 different localities, all of which were characterised by intact or degraded humid forest on sloping ground alongside temporary lentic ponds in narrow valleys. Additional monitoring at a single site revealed that adult M. aurantiaca predominantly used the ponds and surrounding humid forest habitat during the austral summer and moved upslope at the beginning of the austral winter. Effective conservation for this species should therefore include measures to safeguard both forest and aquatic habitat features. Although 62% of localities occurred in sites with a positive conservation status (provisional protected areas or Ramsar sites), there is currently heavy pressure from artisanal mining, logging and agriculture in these areas. Because a further 15% of sites occur on land due to be impacted by mining and an additional 23% were at sites without any biodiversity management, the future of M. aurantiaca in the wild is precarious. A species conservation strategy is therefore needed to produce a cohesive plan for the future which aims to secure as many sites as possible for conservation.