Miracle-dz/UniFAR-FTUs huggingface dataset:
Analisis perbandingan bahan dan jumlah perekat terhadap briket tempurung kelapa dan ampas tebu

The aim of this research was to study the effect of comparative analysis of ingredients and the amount of adhesive on the coconut shell charcoal briquettes and bagasse charcoal. This research used Split Plot Design that consisted of two factors. The first factor is the total ratio of coconut shell charcoal and bagasse charcoal and coconut shell charcoal and bagasse charcoal 1: 1 (L1), 1: 2 (L2) and 1: 3 (L3), while the second factor was the amount of sago adhesive as plots section, consisting of: 10% (P1), 20% (P2) and 30% (P3). The parameters analyzed include: heating value, moisture content, ash and volatile matter. The results showed that the amount of adhesive greatly affected the briquette charcoal produced, the addition of the amount of adhesive would reduce the briquette's heating value, as well as the water content, ash content and evaporation rate increased with the addition of the amount of adhesive. Comparison of coconut shell charcoal and bagasse charcoal can influence to cause higher levels of volatile matter because the level of sugarcane charcoal volatile matter is higher than coconut shell charcoal which has lower volatile matter levels. Judging from the heating value in this study, the best results in this study were in the treatment of P1L1, namely the ratio of coconut shell charcoal and bagasse 1:1 with the amount of sago adhesive 10% with a heating value 5687.45%.
RATIONAL DESIGN AND SYNTHESIS OF CHEMICAL PROBES FOR O-GLCNACASE AND OGT

The attachment of GlcNAc via a β-O-linkage to serine or threonine residues of various nucleocytoplasmic proteins is a common posttranslational modification in multicellular eukaryotes. A glycosyl transferase, UDP-N-acetyl-D-glucosamine: polypeptide-N-acetylglucosaminyl transferase (OGT) acts to install O-GlcNAc while a β-N-acetylglucosaminidase, O-GlcNAcase, removes this modification from proteins. A dynamic relationship between O-GlcNAc and phosphorylation has been proposed and is implicated in cellular signalling and disorders such as Alzheimer disease. In this thesis, the facile syntheses of two series of inhibitors of O-GlcNAcase are described. The potency of these compounds toward OGlcNAcase is also detailed. Several of these compounds are highly potent and selective inhibitors of O-GlcNAcase. Additionally, 2-acetamido-2-deoxy-5-thio-Dglucopyranosose was synthesized as an analogue of GlcNAc. This compound was used for cell studies and to synthesize para-methoxyphenyl 2-acetamido-2deoxy-5-thio-D-glucopyranoside as a potential substrate for O-GlcNAcase. Together, these compounds should serve as useful chemical probes to study the function of O-GlcNAc in cells and in vivo.
Restructuring the inpatient advanced pharmacy practice experience to reduce the risk of contracting coronavirus disease 2019: Lessons from Saudi Arabia

On March 11, 2020, the World Health Organization announced the rapidly spreading epidemic of the coronavirus disease 2019 (COVID‐19) pandemic. Almost all countries started to take proactive precautionary measures to reduce the risk of contracting the virus. The education sector, including pharmacy education, has been drastically impacted by this pandemic. During the outbreak, many hospitals instructed the health profession's schools to restrict or prevent the presence of their students and interns in their hospitals in an effort to limit the spread of the virus.
Sensorial and physicochemical characteristics of herbal noodle enriched with Centella asiatica

F U L L P A P E R Sensorial and physicochemical characteristics of herbal noodle enriched with Centella asiatica Fadzil, N.F. , *Abu Bakar, M.F. , 1,2 Yusop, M.H. M. and Abu Bakar, F.I. Centre of Research for Sustainable Uses of Natural Resources (CoR-SUNR), Faculty of Applied Sciences and Technology, Universiti Tun Hussein Onn Malaysia (UTHM), Hub Pendidikan Tinggi Pagoh, KM1, Jalan Panchor, 84600 Muar, Johor, Malaysia Faculty of Food Science and Nutrition, Universiti Malaysia Sabah, Jalan UMS, 88400 Kota Kinabalu, Sabah, Malaysia
Inclusion of a blend of copaiba, cashew nut shell and castor oil in the protein-energy supplement for grazing beef cattle improves rumen fermentation, nutrient intake and fibre digestibility

Context Essential oils are secondary plant compounds extracted from plants, with potential for the modulation of rumen fermentation. Aims Two experiments, namely one in vivo and another in vitro, were conducted to analyse the effects of a commercial blend of essential oils (EO; copaiba (Copaifera langsdorffii), cashew nut shell (Anacardium occidentale) and castor oil (Ricinus communis) and monensin as dietary feed additives in protein–energy supplements (PES) provided to grazing beef cattle, on ruminal fermentation, intake, total nutrient digestibility and protein dietary efficiency. Methods In the in vivo experiment, four entire Nellore bulls cannulated in the rumen (374 ± 15.66 kg; mean ± s.d.) were used in a 4 × 4 Latin-square design to evaluate the effects of EO concentration and monensin on voluntary intake, digestibility, and rumen and metabolic characteristics of grazing beef cattle provided with supplementation during the rainy season. Treatments were as follows: control (CON; PES without additives); monensin (MON; PES with inclusion of monensin at 20 mg/kg DM consumed); EO150 (PES with inclusion of EO at 150 mg/kg DM consumed); EO300 (PES with inclusion of EO at 300 mg/kg DM consumed). In the in vitro experiment, the effects EO150, EO300 and EO450, MON and CON on DM and neutral detergent-fibre (NDF) digestibility, and total gas production, were evaluated in four consecutive runs using a gas-production (GP) system. Key results In the in vivo experiment, DM intake, forage DM intake, crude protein intake and NDF intake were similar (P > 0.05) between EO150 and MON, but both were greater than those in EO300 and CON (P 0.05) GP, DM and NDF digestibility compared with the control, but EO300 and EO450 decreased GP at 12 and 24 h and decreased DM and NDF digestibility at 48 h compared with the control, MON and EO150. Conclusions In vivo and in vitro results suggested that EO (copaiba oil, cashew nut shell and castor) at low doses (150 mg/kg DM) has the potential to improve ruminal fermentation in grazing beef cattle receiving supplements, but medium and high doses of EO can have adverse effects. Implications EO blends could be an alternative to MON for grazing beef cattle with access to supplements.
Evidence on study abroad programmes: Data and indicators

There is a large consensus among policymakers and scholars that spending time abroad during university studies is highly beneficial to students in terms of their professional and personal development. This calls for an increasing amount of resources to be channelled to support students willing to study abroad. However, this significant investment in international student mobility programmes needs to be accompanied by a systematic monitoring of who studies abroad and what are the effects associated with studying abroad. The availability of appropriate data and indicators is essential to be able to do this. This paper provides an overview of existing national and international data sources on international student mobility. Both administrative and survey data are considered. It also looks at the wide range of indicators that have been used to measure participation in study abroad programmes and its effects on labour market and non-labour market outcomes. Suggestions about new indicators covering dimensions that perhaps have been overlooked or under-explored are given.
EEG Spindle and K-Complex Densities During N2 Sleep Increase with Ageinto Adulthood and are Uncorrelated to Baseline Autonomic Tone

The non-rapid eye movement (NREM) sleep is considered a true resting state for the brain, yet the physiologic drivers of neural activity in this phase remain undetermined. Neural activity may be endogenously driven to compensate for minimal sensory stimulation, or by physiologic processes associated with development, or the autonomic tone. To address this issue, we examined brain activity and autonomic tone during stage 2, NREM sleep over a cohort of 93 subjects, from toddlers to young adults. Brain activity was quantified as total counts of EEG spindles and spontaneous K-complexes over 30 minutes of uninterrupted sleep. Autonomic tone during sleep was measured as baseline heart rate and amplitude of respiratory sinus arrhythmia. Blood pressure was also measured at rest. On average, spindle and K-complex counts increased by 8 and 1 units, respectively, with each additional year of development. Furthermore, spindle and K-complex densities were strongly correlated even after adjusting for age, which suggests a common underlying mechanism. Across subjects, spindles were on average 15 times more abundant than spontaneous K-complexes. Gender did not significantly influence any of these trends. Regarding autonomic tone, spindles and K-complex densities were anticorrelated with baseline heart rate and positively correlated with blood pressure, but these correlations are explained by natural covariations with age. Finally, neither respiratory rate nor sinus arrhythmia correlated with spindle or K-complex density, after adjusting for age. These results collectively demonstrate that spindle and spontaneous K-complex densities increase progressively with age during development into adulthood and are unrelated to baseline autonomic tone. those studies have focused on fast time scales, that is, on transient interactions between brain activity (i.e. K-complex waveforms) and autonomic changes, and have ignored tonic effects on larger time scales, that is, the relationship between baseline autonomic tone and baseline EEG activity. Here, we have investigated these tonic effects by focusing on the spindle and K-complex counts over long periods of uninterrupted N2 sleep and demonstrated that they are uncorrelated to autonomic parameters after adjusting for natural covariations of all of these variables with age. We thus conclude that tonic neural activity during N2 sleep, quantified as the densities of sleep and K-complexes, increases progressively with age during development into adulthood, but is unrelated to the baseline autonomic tone.
Positive reappraisal moderates depressive symptomology among adolescent bullying victims

Abstract Objective Recent research has identified three distinct types of bullying‐victimisation; overt, reputational, and relational. While bullying‐victimisation as a single construct is known to be associated with depression among adolescents, this relationship is unclear when applied to distinct types. The aim of the present study is to investigate the relationship between overt, reputational, and relational types of bullying‐victimisation and depressive symptomology among adolescents. Further, the cognitive coping strategy “positive reappraisal” is explored as a moderating factor in these relationships. Method Data were collected through online surveys completed by 338 adolescents aged 12–18-years. Data were analysed through multiple regression and moderation analysis. Results It was found that bullying as a single construct predicted levels of depression. As unique constructs, reputational and relational bullying‐victimisation were demonstrated to be associated with depression symptomology while overt bullying‐victimisation was not. Positive reappraisal was found to moderate the relationships between reputational and relational bullying‐victimisation and depression, but not between overt bullying‐victimisation and depression. Conclusion This study highlights the importance of considering subtypes of bullying‐victimisation in future research regarding adolescent's mental health. That positive reappraisal was found to be helpful in reducing depressive symptomology among adolescent bullying victims suggests investigation of other cognitive coping strategies is warranted.
Types and Scales of Enterprises Being Run by the Women Entrepreneurs of Self-help Groups in Andhra Pradesh

The present investigation was carried out in three districts of Andhra Pradesh viz., Chittoor (from Rayalaseema region), East Godavari (from Coastal region) and Srikakulam (from North Coastal region) during 2016-18. About 63 types of enterprises being run by 240 entrepreneurs depending upon availability of natural resources and demand in the local area coming to a total of 286 enterprises. Provision shop (16.08%) was the main choice of the respondents, followed by Tailoring (13.29%), Dairy (6.99%), equal (4.55%) percentage with Small hotel/Tiffin centre and Sarees and dress materials/ Cloth business and Fancy shop (4.20%). One-third (33.22%) of the SHG members running the enterprise with an income range of ` 50,001-1,00,000. Only 0.70 per cent of the SHG members running the enterprise with an income range of ` 5,00,001 and above. More than half (56.99%) of the enterprises being run by the SHG women entrepreneurs were the primary sources of income for their family. There was a significant association between the types of enterprises and scale of enterprise.
CEO Diversity, Political Influences, and CEO Turnover in Unstable Environments: The Romanian Case

This work expands the literature on a less studied topic, the Chief Executive Officer (CEO) turnover in post-communist economies, analyzed during an unstable and ambiguous economic and financial environment. For the period 2005–2010, the results indicate the political inference in CEO turnover decision for the Romanian listed companies. In this period, with great turmoil in the economy determined by the financial crisis of 2008, we also find that CEO gender helps to explain the probability of changing the CEO. Moreover, this paper empirically tests if the financial and corporate governance determinants that are validated in the existing literature work for the Romanian listed companies. We reinforce that CEO turnover decision is negatively related to accounting-based performance. We find evidence of the “voting with their feet” behavior of institutional investors, and of the lack of Board of Directors monitoring. The CEO–Chairman duality and the controlling power of the largest shareholder act as entrenchment mechanisms.
Enabling Mutant Generation for Open- and Closed-Source Android Apps

Mutation testing has been widely used to assess the fault-detection effectiveness of a test suite, as well as to guide test case generation or prioritization. Empirical studies have shown that, while mutants are generally representative of real faults, an effective application of mutation testing requires “traditional” operators designed for programming languages to be augmented with operators specific to an application domain and/or technology. The case for Android apps is not an exception. Therefore, in this paper we describe the process we followed to create (i) a taxonomy of mutation operations and, (ii) two tools, MDroid+ and MutAPK for mutant generation of Android apps. To this end, we systematically devise a taxonomy of 262 types of Android faults grouped in 14 categories by manually analyzing 2,023 software artifacts from different sources (e.g., bug reports, commits). Then, we identified a set of 38 mutation operators, and implemented them in two tools, the first enabling mutant generation at the source code level, and the second designed to perform mutations at APK level. The rationale for having a dual-approach is based on the fact that source code is not always available when conducting mutation testing. Thus, mutation testing for APKs enables new scenarios in which researchers/practitioners only have access to APK files. The taxonomy, proposed operators, and tools have been evaluated in terms of the number of non-compilable, trivial, equivalent, and duplicate mutants generated and their capacity to represent real faults in Android apps as compared to other well-known mutation tools.
Yield stability and adaptability of lowland sorghum (Sorghum bicolor (L.) Moench) in moisture-deficit areas of Northeast Ethiopia

Abstract Genotype-environment interaction (GxE) is a common phenomenon in sorghum. The effect of GxE can be reduced by identifying stable genotypes across environments. An investigation was conducted to study yield stability and adaptability of 13 sorghum genotypes across six environments. Additive Main-effect and Multiplicative Interaction (AMMI), Genotype and Genotype-Environment interaction (GGE), and stability analyses were computed. The AMMI analysis explained 68.67% of the GxE variance, while GGE captured 74.41% of the GGE variance. GGE analysis identified Kobo (KB13 and KB14) as a suitable environment for selecting generally adapted lowland sorghum genotypes. The GGE and the stability analyses further identified G13 and G2 as the least and the most desirable sorghum genotypes, respectively. Genotype G2 has high level of adaptability to the northeastern parts of Ethiopia, as evidenced by its high-yielding ability, stability and early maturity. This genotype (G2; WSV-387 x E-36-2) was released with the approval of the National Variety Release Committee in 2017. Need-based large volume seed production, dissemination over a wider area and the consequent adoption of the variety by target farmers would be convenient and fast.
Thyroid hormone receptors in the heart

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Intraday Momentum and Return Predictability: Evidence from the Crude Oil Market

Abstract Intraday return predictability has firstly been identified in the equity markets, and we extend the analysis to the crude oil market by using high-frequency United States Oil Fund data from 2006 to 2018. We find a different intraday prediction pattern in the oil market, where only the first half-hour returns positively predict the last half-hour returns. A market timing strategy based on these findings generates substantial profits. We further decompose the first half-hour return into its overnight and open half-hour components and find that the former contains more predictive information. The economic mechanisms of infrequent portfolio rebalancing and the presence of late-informed investors explain our findings. Notably, unlike equity markets, the oil market exhibits a unique intraday trading volume pattern due to the release of two routine oil inventory announcements. However, the information contained in the inventory announcements does not offer predictability for the last half-hour returns.
Social media, civil unrest and government responses: the Zimbabwean experience

ABSTRACT This article discusses the discontent that increased against the Robert Mugabe led government as a result of grave socio-economic and political grievances, and in the context of accessible social media platforms which mobilised and empowered disenfranchised Zimbabweans to challenge the regime after the 2013 elections. Among other factors, the mounting discontent was caused by the belated payment of civil servants’ salaries, inability to create employment opportunities, refusal to enact electoral reforms, rampant corruption and the introduction of import ban restrictions. This led to the formation of civic organisations which demanded the resignation of Mugabe and these included, but were not limited to, #Tajamuka and #ThisFlag. In response, the Mugabe led government used rigid and repressive measures targeting the protesters, as well as traditional and social media platforms to safeguard itself.
Numerical approximation of a two-dimensional model of non-isothermal reactive liquid chromatography involving slow rates of adsorption–desorption kinetics

Abstract A two-dimensional general rate model of non-isothermal reactive column chromatography is formulated considering homogenous and heterogeneous reaction rates, slow rates of adsorption–desorption kinetics, and enthalpies of adsorption and reaction. The model is expressed by a system of six nonlinear partial differential equations (PDEs) coupled with algebraic expressions for the adsorption and reaction rates. The nonlinearity of adsorption isotherm and reaction term hinders the derivation of analytical solutions. For that reason, a flux-limiting high-resolution finite volume scheme is suggested to numerically approximate the model equations. The effects of several kinetic and thermodynamic parameters are rigorously analyzed on the reactant conversion and components separation. Graphical Abstract
Hyphenated High Performance Liquid Chromatography–Tandem Mass Spectrometry Techniques for the Determination of Perfluorinated Alkylated Substances in Lombardia Region in Italy, Profile Levels and Assessment: One Year of Monitoring Activities During 2018

In this research paper, we report a hyphenated technique based on ultra-high performance liquid chromatography–tandem mass spectrometry for the determination of twelve Perfluorinated Alkylated Substances in surface and groundwater samples from Lombardia Region during the monitoring activities in 2018 as new emerging and toxic pollutants. A green analytic method, developed by using an online Solid Phase Extraction coupled with UHPLC-MS/MS and previously validated, was applied for 4992 determinations conducted on 416 samples from 109 different sampling stations. Among the results, PFOS, PFOA, PFBA, PFBS, PFPeA and PFHxA were identified as the most abundant analytes detected. PFASs concentrations, in most cases, were below the limits of quantification and, in the cases where the limits of quantification have been exceeded, the values found were lower than Italy directive. PFOS is an exception and in fact this compound was detected in 76% of analyzed samples (surface and ground waters). Solid phase extraction with high performance liquid chromatography–tandem Mass Spectrometry has proved to be a very good Hyphenated techniques able to detect low concentrations of pollutants in surface and groundwater samples.
Serum paraoxonase enzyme activity after balneotherapy in patients with fibromyalgia

Received 13-01-2019 Accepted 12-02-2020 Available Online 01-03-2020 Published 30-03-2020 1 Cumhuriyet University, Faculty of Medicine, Dept of Physical Medicine and Rehabilitation, Sivas, TR 2 Cumhuriyet University Faculty of Medicine, Dept of Biochemistry, Sivas, TR * Corresponding Author: Ahmet Karadağ E-mail: ahmetkaradag@hotmail.com Serum paraoxonase enzyme activity after balneotherapy in patients
Beyond Tourismphobia

This chapter discusses the factors that have led to the emergence of expressions of criticism toward tourism. This review serves to frame the original contribution of this text: a theoretical model that clarifies the defining features of the main attitudes towards tourism. Merton’s model is here adjusted for the analysis of a new relationship between social ends and economic means. In this case, the end is economic progress. The way is the tourism, conceived as a massive social phenomenon. The relation between goals and means generates tensions. Its management derives in strategies of adaptation that include different ways of identification or discussion. The five types of adaptation of the new model are useful for addressing subject positions, political discourses, or attitudinal dispositions towards tourism. To illustrate this typology a purposive sampling of news on the tourismphobia has been selected, with no statistical generalization reflecting the constituent elements of each of the types: legitimization, innovative criticism, resignation, radical criticism, and subversive utopia.