doença arterial periférica Association between frailty and peripheral arterial disease

Background: Frailty has been associated with lifestyle, chronic diseases, and genetic alterations and with high levels of proinflammatory proteins, justifying the relationship proposed by the emerging literature that seeks associations between frailty and cardiovascular diseases. Objective: To investigate clinical and sociodemographic factors associated with frailty, emphasizing the relationship with peripheral arterial disease. Methods: Medical records of 76 patients were analyzed, considering the results of the ankle-brachial index test, fragility, sociodemographic and clinical variables. After the descriptive analysis, differences between groups were tested by chi-square test, student’s t-test and Tukey’s post hoc test, when they were appropriated. The value of p < 0.05 for statistically significant differences was considered. Results: The prevalence of frailty in the study sample was 22.3%, and 47.3% for pre-frail. Frailty was associated with female gender, hypertension, dyslipidemia and level of education. Changes in ankle-brachial index test were statistically associated with frailty. Conclusion: The results of this research show the necessary targeted efforts to prevent and treat frailty. Key-words: Peripheral arterial disease, Cardiovascular disease, Chronic disease, Fragility. RESUMO Introdução: Fragilidade tem sido associada com hábitos de vida, doenças crônicas, alterações genéticas e níveis elevados de proteínas pró-inflamatórias, justificando a emergente relação proposta entre Fragilidade e doenças cardiovasculares. Objetivo: Investigar fatores clínicos e sociodemográficos associados à Fragilidade, enfatizando-se a relação com a doença arterial periférica. Métodos: Foram analisados prontuários de 76 pacientes, considerando-se valores do Índice Tornozelo-Braquial (ITB), Fragilidade, variáveis sociodemográficas e clínicas. Após análise descritiva, testou-se as diferenças pelo teste Qui-quadrado, t de Student e Post Hoc de Tukey, quando apropriado. Considerou-se p < 0,05 para diferenças significativas. Resultados: A prevalência de frágeis foi de 22,3% e de pré-frágeis 47,3%. Fragilidade associou-se ao sexo feminino, hipertensão arterial, dislipidemia e ao analfabetismo funcional. Alterações no ITB foram estatisticamente relacionadas à Fragilidade. Conclusão: Os resultados dessa pesquisa alertam para necessidade de esforços direcionados a intervenções para prevenção e tratamento adequado da Fragilidade. Palavras-chave: Doença arterial periférica, Doenças cardiovasculares, Doenças crônicas, Fragilidade. Associação entre fragilidade e doença arterial periférica Association between frailty and peripheral arterial disease Correspondence: Natália Rodrigues dos Reis, Avenue José de Assis Vieira Journalist, 19, Jardim América, Rio Pomba MG, Brazil. E-mail: natyrreis@hotmail.com Original Article Sergio Ribeiro Barbosa1 , Natália Rodrigues dos Reis2 , Henrique Novais Mansur3 1. São Lourenço College, Physical Education Department, São Lourenço, MG, Brazil. 2. Federal University of Juiz de Fora, Juiz de Fora, MG, Brazil. 3. Federal Institute of Southeastern Brazil, Education Academic Department, Physical Education and Health Center, Rio Pomba, MG, Brazil. Received on: January 7, 2020; Accepted on: April, 16, 2020. Brazilian Journal of Exercise Physiology open acess ISSN: 2675-1372 RBFEx How to cite: Barbosa SR, Reis NR, Mansur HN. Association between frailty and peripheral arterial disease. Rev Bras Fisiol Exerc 2020;19(2):124-133. DOI: https://doi.org/10.33233/rbfe.v19i2. 3891 125 Barbosa et al. Frailty and peripheral arterial disease