Miracle-dz/UniFAR-FTUs huggingface dataset:
Miss-and-run: Factors contributing to two-vehicle phantom vehicle crashes in Florida

Abstract Objective: Phantom vehicle crashes (PVCs), or miss-and-run crashes, are a topical issue in car insurance coverage because of controversies over testimony and compensation. However, no peer-reviewed literature has examined the perceptions and deliberations involved in this infrequent type of car crash. A novel taxonomy of roadway traffic crashes is proposed in this study on the basis of whether physical collisions did occur (hit or miss) and whether the perpetrators stayed at the crash scene (stay or run). In this way, this study poses the issue of PVCs within the scope of traffic safety research and aims to investigate the statistically significant factors that are likely to induce PVCs. Methods: A binary logistic regression method was adopted to model the probability and occurrence of 2-vehicle PVCs (TV-PVCs) in Florida. Data derived from the Crash Analysis Reporting system in 2012–2014 consisted of 45,319 2-vehicle crashes, of which 1,376 (3.04%) were confirmed as positive TV-PVCs. Sixteen factors with 50 variables on crash information, roadway characteristics, and environmental conditions were included in the original consideration of the TV-PVC model. Results: The results indicated that a 2-vehicle crash is more likely to be a PVC when the crash happens on weekends, on roadways with no traffic control or speed control, full access control; on curving and sloping roadways; on roadways of National Highway System; and in low-density and other areas. A TV-PVC is less likely to occur on dry roads, in daylight, or at intersections or driveways. Moreover, alcohol involvement in a 2-vehicle crash is associated with hit-and-stay crashes than PVCs, and uninsured motorists are more likely to be the victims of PVCs because they tend to avoid physical collisions due to the potential self-paid loss. Conclusions: Several conclusions for better understanding the occurrence of PVCs are proposed for traffic management departments and car insurers. Cautious driving behavior including concentrated attention and deliberate lane changes should be encouraged for motorists to engage in appropriate levels of driving freedom, and drunk driving should be strictly supervised to keep motorists behind the wheel conscious. Car insurance is encouraged to compensate for economic loss resulting from roadway crashes. Road monitoring systems with well-performing illumination devices are recommended to help drivers provide potent testimony for compensation claims.
Genome-wide association study in Turkish and Iranian populations identify rare familial Mediterranean fever gene (MEFV) polymorphisms associated with ankylosing spondylitis

Ankylosing spondylitis (AS) is a highly heritable immune-mediated arthritis common in Turkish and Iranian populations. Familial Mediterranean Fever (FMF) is an autosomal recessive autoinflammatory disease most common in people of Mediterranean origin. MEFV, an FMF-associated gene, is also a candidate gene for AS. We aimed to identify AS susceptibility loci and also examine the association between MEFV and AS in Turkish and Iranian cohorts. We performed genome-wide association studies in 1001 Turkish AS patients and 1011 Turkish controls, and 479 Iranian AS patients and 830 Iranian controls. Serum IL-1β, IL-17 and IL-23 cytokine levels were quantified in Turkish samples. An association of major effect was observed with a novel rare coding variant in MEFV in the Turkish cohort (rs61752717, M694V, OR = 5.3, P = 7.63×10−12), Iranian cohort (OR = 2.9, P = 0.042), and combined dataset (OR = 5.1, P = 1.65×10−13). 99.6% of Turkish AS cases, and 96% of those carrying MEFV rs61752717 variants, did not have FMF. In Turkish subjects, the association of rs61752717 was particularly strong in HLA-B27-negative cases (OR = 7.8, P = 8.93×10−15), but also positive in HLA-B27-positive cases (OR = 4.3, P = 7.69×10−8). Serum IL-1β, IL-17 and IL-23 levels were higher in AS cases than controls. Among AS cases, serum IL-1β and IL-23 levels were increased in MEFV 694V carriers compared with non-carriers. Our data suggest that FMF and AS have overlapping aetiopathogenic mechanisms. Functionally important MEFV mutations, such as M694V, lead to dysregulated inflammasome function and excessive IL-1β function. As IL-1 inhibition is effective in FMF, AS cases carrying FMF-associated MEFV variants may benefit from such therapy.
“DENGUE ENCEPHALITIS – A RARE MANIFESTATION OF DENGUE FEVER.”

We report a case of dengue fever with features of encephalitis from Northern India. A 22 years female presented with history of high-grade fever with chills for 2 days followed by altered sensorium and MRI brain, revealed characteristic changes consistent with Encephalitis with hemorrhage mainly involving the bilateral thalami. The diagnosis of dengue was confirmed by the presence of dengue antigen in the serum and the presence of dengue antibodies in the serum as well as cerebrospinal fluid. Dengue is not primarily a neurotropic virus and encephalopathy is an uncommon finding in dengue. This case explains the importance of considering dengue encephalitis as the differential diagnosis of fever with altered sensorium, especially in countries like India where dengue is rampant.
The Dynamics Information Technology and Systematic Risk

ABSTRACT Systematic risk is the degree to which a firm is sensitive to changes in the overall economy. It is a core concept in finance theory, and is an important measure of firm performance. While much research has looked at the relationship between IT and direct risk measures such as earnings volatility, research is lacking on this core outcome. Additionally, we know from prior research that impacts from IT can change over time. Therefore, we examine the association between information technology and systematic risk over time. We investigate this association using a sample of 2,417 firm-years from 659 unique firms over the years 2003-2007. We find that increased levels of IT intensity are associated with greater systematic risk contemporaneously but result in significant reductions in systematic risk associated with three- and four- year lagged effects. We propose that this occurs due to intangible capital formation and increased flexibility.
Patch-Based Document Denoising

Document denoising is one of the most challenging tasks in any optical character recognition system, especially when the noise type is different from white noise. Noise types are wide and, hence an effective denoising algorithm should be able to deal with different noise types. This paper introduces two denoising algorithms that are able to remove noise from Arabic documents. Our approaches are based on sparse representations over a learned dictionary and denoising auto-encoders, which have provided best state of the art results for natural images denoising. The experiments show that those two algorithms are promising in document denoising, as they provide the ability of learning a prior knowledge of clean character models to use them in the denoising process.
Efficacy and Safety of Low-Dose Versus Standard-Dose Alteplase Regimens in Patients with Acute Ischaemic Stroke.

BACKGROUND The use of intravenous recombinant tissue plasminogen activator, alteplase, at a dose of 0.9 mg/kg is an effective treatment for patients with acute ischaemic stroke; this dose is also associated with high intracerebral haemorrhage rates. The aim of this study was to evaluate whether the low-dose alteplase treatment is as effective and safe as the standard-dose regimen. SUBJECTS AND METHODS This was a retrospective, single-centre study, and data were collected from the Hospital Stroke Registry. Based on the severity of stroke and the risk of intracerebral haemorrhage, patients were divided into two groups according to the alteplase doses given; the low-dose (0.6 mg/kg) group (n=45) and the standard-dose (0.9 mg/kg) group (n=165). Ninety-day outcomes measured as modified Rankin score and National Institute for Health Stroke Scale (NIHSS) score, as well as symptomatic intracerebral haemorrhage and mortality rates were analysed. RESULTS The standard-dose group had a slightly more favourable outcome (Rankin score 0-2) at 90 days after alteplase treatment than the low-dose group (64.24% vs. 53.33%), but the difference was not significant. The total intracerebral haemorrhage rate and mortality rate at 90 days were higher in the standard-dose group than in the low-dose group (21.2% vs. 13.3% and 6.1% vs. 0.0%, respectively), but these differences were not statistically significant. CONCLUSION The low-dose alteplase treatment applied to the patients with high intracerebral haemorrhage risk had comparable efficacy and safety profile to the standard-dose regimen.
Combined DFT and operando Spectroscopic Study of the Water-Gas Shift Reaction over Ceria based Catalysts: The Role of the Noble Metal and Ceria Faceting

: Ceria loaded with noble metals (Cu, Au) is a highly active material for the low-temperature water-gas shift reaction (LT-WGSR), but nevertheless details of the metal support interaction as well as the role of the ceria surface termination and the metal loading are still unclear. Using operando Raman and UV/Vis spectroscopy combined with theoretical density functional theory (DFT) calculations, we aim at a molecular-level understanding of LT-WGSR catalysts. In particular, by using this combined approach, we are able to draw conclusions about the reducibility state of the ceria support during reaction conditions. Our results show that the defect formation energy of the support does not play a major role for the WGSR, but rather other reaction steps such as the dissociation of water or the desorption of CO 2 .
Enhanced Carbon Nanotubes Light Emission Integrated with Photonic SOI Ring Resonators

In this contribution we present our recent results towards the integration of carbon nanotubes onto silicon-on-insulator (SOI) platform for the implementation of light sources. We experimentally demonstrate two-orders of magnitude enhancement of semiconductor single walled carbon nanotubes (s-SWCNTs) emission in fully integrated silicon microresonators.
Clinical Prognostic Factors and Outcome in Pediatric Osteosarcoma: Effect of Delay in Local Control and Degree of Necrosis in a Multidisciplinary Setting in Lebanon

PURPOSE Outcomes in pediatric osteosarcoma have dramatically improved over the past few decades, with overall survival rates of 70% and 30% for patients with localized and metastatic disease, respectively. PATIENTS AND METHODS We retrospectively reviewed clinical characteristics and outcomes of 38 patients treated between 2001 and 2012 at a single institution in Lebanon. All patients received a uniform three-drug chemotherapy regimen consisting of cisplatin, doxorubicin, and methotrexate. Ifosfamide and etoposide were added to the adjuvant treatment regimen in case of metastatic disease and/or poor degree of tumor necrosis (< 90%). RESULTS After a median follow-up of 61 months (range, 8 to 142 months), patients with localized disease had 5-year overall and event-free survival rates of approximately 81% and 68%, respectively, whereas for metastatic disease, they were approximately 42%. The most common primary site was the long bones around the knee (n = 34; 89.5%). Six patients (15.8%) had metastatic disease to lungs, and three (7.9%) had synchronous multifocal bone disease with lung metastases. Adverse prognostic factors included nonlower extremity sites, metastasis, poor degree of necrosis, and delay of more than 4 weeks in local control. In bivariable analysis, only degree of necrosis was a prognostic predictor for survival and disease recurrence. CONCLUSION Treatment of pediatric osteosarcoma in a multidisciplinary cancer center in Lebanon resulted in survival similar to that in developed countries. Delay in local control was associated with worse outcome. The only statistically significant inferior outcome predictor was poor degree of necrosis at the time of local control.
Trauma demography and clinical epidemiology of motorcycle crash–related head injury in a neurosurgery practice in an African developing country

Abstract Objective: Though motor vehicle crashes (MVCs) were the main cause of head trauma from road traffic injuries (RTIs), motorcycle crashes (MCCs) are now a major cause of RTI-related head injury (HI) in many developing countries. Methods: Using a prospective database of HIs from a neurosurgical practice in a sub-Saharan African developing country, a cross-sectional survey was conducted for the trauma demography and clinical epidemiology of this MCC-related HI. Results: Motorcycle crashes accounted for 57% (473/833) of all RTI-related HIs in this registry. The victims, with a mean age of 33.1 years (SD = 18.3), consisted mainly of males (83.1%), those of low socioeconomic status (>90%), and those aged between 20 and 40 years old (56%). MCCs involved only riders in 114 cases (114/473, 32.1%), of which 69% were motorcycle–motorcycle crashes. The HI was moderate–severe in 50.8%; clinical symptomatology of significant HI included loss of consciousness (92%), anisocoria (35%), Abbreviated Injury Scale head (AIS–head) score > 3 (28%), and CT-Rotterdam score > 3 (30%). Extracranial systemic injury involved the limbs most frequently, with an Injury Severity Score (ISS) >25 in 49%. The fatality rate was 24%. MCC-related HI among pedestrian victims involved more vulnerable age groups (the young and elderly) but have lower mean ISS compared to motorcycle passengers (mean ISS = 23.5 [11.6] vs. 27.4 [13.0]; 95% confidence interval [CI], 1.27–6.49; P = .004). In addition, compared to a contemporary cohort of MVC-related HIs in our registry, MCC victims were older (mean age 34.8 years [18.0] vs. 30.8 [18.4]; P = .002); had higher proportions of certain extracranial trauma like long bone fractures (71 vs. 29%; P = .02); and suffered fewer surgical brain lesions (25.5 vs. 17.2%; P = .004). Conclusions: Motorcycle crashes are now a significant threat to the heads, limbs, and lives of vulnerable road users in developing countries.
RNA and Toll-Like Receptor 7 License the Generation of Superior Secondary Plasma Cells at Multiple Levels in a B Cell Intrinsic Fashion

Secondary plasma cells (PCs) originate from memory B cells and produce increased levels of antibodies with higher affinity compared to PCs generated during primary responses. Here we demonstrate that virus-like particles (VLPs) only induce secondary PCs in the presence of toll-like receptor (TLR) 7 and if they are loaded with RNA. Furthermore, adoptive transfer experiments demonstrate that RNA and TLR7 signaling are required for secondary PC generation, both at the level of memory B cell as well as PC differentiation. TLR7-signaling occurred in a B cell intrinsic manner as TLR7-deficient B cells in an otherwise TLR7-competent environment failed to differentiate into secondary PCs. Therefore, RNA inside VLPs is essential for the generation of memory B cells, which are competent to differentiate to secondary PCs and for the differentiation of secondary PCs themselves. While we have not tested all other TLR or non-TLR adjuvants with our VLPs, these data have obvious implications for vaccine design, as RNA packaged into VLPs is a simple way to enhance induction of memory B cells capable of generating secondary PCs.
ANALISIS PEMBELAJARAN DI MASA PANDEMIK COVID 19 (LITERATUR REVIEW)

Latar belakang : Perubahan pola pembelajaran saat ini terlihat masif dilakukan di semua jenjang pendidikan akibat pandemi Covid-19. Penelitian ini bertujuan untuk menganalisis studi literature studi pustaka pembelajaran online berbasis proyek di tengah pandemi Covid-19 yang berefek pada kebijakan belajar di rumah. Sistem pembelajaran online berbasis proyek memberikan banyak peluang untuk mengakses bahan ajar oleh warga pembelajar. Metodologi penelitian dengan melakukan literature review dari beberapa artikel baik internasional maupun nasional yang dicari dengan mempergunakan google scholar dan sciencedirect, mengisihkan 29 artikel dengan kata kunci pembelajaran dan pandemic covid 16. Hasil review pada 8 artikel internasional dan 17 nasional menyebutkan kendala yang ditemukan dengan cara pembelajar virtual adalah kesulitan dengan jaringan quota, strees dengan tugas pelajaran dengan deadline waktu yang singkat dan ingin siswa mahasiswa untuk ketemu guru dan dosen di dalam kelas, sementara untuk beberapa yang positif didapat tinggi tanggung jawab dari siswa dan mahasiswa dengan tugas yang diberikan, meningkatkan motivasi baik guru/dosen juga siswa dan mahasiswa dalam mempergunakan media online dalam proses pembelajaran. Simpulan: Proses pembelajaran yang paling diminat dengan mempergunakan whatsapp dan Zoom, kendala yang ditemui meningkatnya tinggi tress mahasiswa maupun guru, dinegara maju dan Indonesia dosen sudah membuat suatu model khusus untuk pembelajaran dalam jaringan. Background : Changes in learning patterns currently appear to be massive at all levels of education due to the Covid-19 pandemic. This study aims to analyze literature studies, library research, project-based online learning in the midst of the Covid-19 pandemic which has an effect on home learning policies. Project-based online learning systems provide many opportunities to access teaching materials by learning citizens. The research methodology is by conducting a literature review of several articles both international and national that are searched by using google scholar and science direct, removing 29 articles with the keywords learning and the COVID-19 pandemic. The review results from 8 international and 17 national articles mention the obstacles found by the learners' way virtual is the difficulty with the quota network, stresses with lesson assignments with short deadlines and wanting students to meet teachers and lecturers in the classroom, while for some positive ones get high responsibility from students and students with given assignments, increase good motivation teachers / lecturers as well as students and students in using online media in the learning process. Conclusion: The learning process that is most interested in using WhatsApp and Zoom, the obstacles encountered are the increasing tress of students and teachers, in developed countries and Indonesia a lecturer makes a special model for online learning.
Studies on Correlation and Path Analysis for Yield and its Contributing Traits in Brinjal (Solanum melongena L.)

Brinjal (Solanum melongena L., 2n = 24), a member of the Solanaceae family, is the most common and popular vegetable crop of India. It grown in almost all parts of India yearround and is a major source of income for small and marginal farmers. It is being grown extensively in India, Bangladesh, Pakistan, China and Philippines. India is the second major producer of brinjal in the world after China (Ravali et al., 2017). Due to its highest production potential and availability of the produce to consumers, it is also called as poor man’s vegetable (Kumar et al., 2014). India is a major producer of brinjal in the world and it is grown in area of 648 thousand hectares with estimated annual production of 12,303 thousand metric tonnes with a productivity of 18.98 metric tonnes per hectare. In Maharashtra, it is grown in an area of 35,859 hectare, with an annual production of 667,640 metric tonnes and productivity of 18.61 metric tonnes per hectare which is less than the national average (Anon., 2018-19).
Agency mission statements provide insight into the purpose and practice of conservation

ABSTRACT Debates among scholars reveal rifts in the conservation community concerning the purposes of conservation that might be explained by shifting public values. We examined mission statements of 50-state fish and wildlife agencies in the U.S. to determine how agencies articulate conservation goals. Agency mission statements often expressed multiple goals, both human (e.g., development) and wildlife (e.g., preservation) focused. Results indicated that as the proportion of mutualists within a state’s citizenry increased, mission statements were less likely to cite economic use, and the provisioning of recreational opportunities as goals, and more likely to express the idea that nature/wildlife is a beneficiary. A separate analysis of agency decision-making bodies indicated these bodies were predominately occupied by men and sportspersons. Given the tendency of men and sportspersons to align with domination value orientations, the composition of agency decision-making bodies may prevent adoption of goals that reflect broader changes in societal values.
CuS/Prussian blue core–shell nanohybrid as an electrochemical sensor for ascorbic acid detection

An electrochemical sensor based on core–shell nanostructured copper sulfide@Prussian blue composites (CuS@PB) was investigated for ascorbic acid (AA) detection. CuS nanoparticles (NPs) were prepared by a hydrothermal method, then core–shell CuS@PB nanohybrid was fabricated through in situ synthesis of PB on CuS NPs. Taking advantage of their enhanced properties, a novel electrochemical AA sensor was developed by drop-coating of CuS@PB nanohybrid on glassy carbon electrode (GCE). As expected, electrochemical observations showed that CuS@PB/GCE presented higher electrocatalytic performance of AA than PB/GCE, with a wide linear range (5–3875 μM, R = 0.9997), fast response time (<3 s), high sensitivity (256.91 μAmM−1cm−2), as well as a low limit of detection (0.24 μM at a signal-to-noise ratio of 3). Additionally, the CuS@PB/GCE showed excellent reproducibility, storage stability, anti-interference, and selectivity. The application of a CuS@PB/GCE sensor for an AA assay in beverage samples achieved satisfactory results, demonstrating great prospects for the quantitative detection of AA in various fields.
Pragmatic content in EFL textbooks: an investigation into Vietnamese national teaching materials

Recent research studies in ESL/EFL contexts worldwide have shown a gap between the findings of pragmatics research and how the English language is actually taught and learnt in EFL classrooms, as well as a paucity of pragmatic information provided in ESL/EFL textbooks. Utilizing content analysis, this study explores the provision of pragmatic content in the current national EFL textbook series, which was first published in 2012 and has been used nationwide for Vietnamese upper-secondary school students since the school year 2018-2019. These materials include the aim of facilitating the development of students’ communicative competence in English in their overall objectives, which, as we will argue in this paper, implies that pragmatic competence is also a goal. However, results from this study show that this series includes quite a low level of explicit information about pragmatics, which is present in only 5.5% of pages in the student books and does not appear at all in the teacher manuals. In addition, the explicit presentation of different elements potentially contributing to the learning of pragmatics was found to be quite infrequent. These findings suggest that there is a need for supplementing these EFL textbooks with additional materials and activities, for considering pragmatics as part of the textbook design process, and for enhancing teachers’ ability to incorporate pragmatics in their classroom practices.