Miracle-dz/UniFAR-FTUs huggingface dataset:
Obstetric complications following conservative treatment of Cervical Intraepithelial Neoplasia

Treatment for cervical intraepithelial neoplasia (CIN) has been correlated with adverse reproductive morbidity in subsequent pregnancies. This review provides a summary of the risks, potential mechanisms and current obstetric management of women previously treated for CIN. Background The introduction of an organised screening programme in the UK in 1988 has significantly decreased the incidence and mortality rates of invasive cervical cancer (Quinn et al., 1999) through detection and treatment of the pre-malignant lesions of the uterine cervix, cervical intraepithelial neoplasias (CIN). In 2013-14, 3.4 million women aged between 25-64 years attended cervical screening in England (77.8% of the eligible population), and 199,322 were referred for colposcopy. During the same period almost 22,000 excisional treatments and around 1000 more ablative procedures for CIN were carried out (Health and Social Care Information Centre, 2012). Until recently, local conservative treatment for cervical disease, excisional or ablative, was thought to have minimal complications, mainly related to small risk of haemorrhage and infection. Several studies published in the last decade documented that treatment for CIN adversely affects reproduction and led to major changes in clinical practice. The mean age for having conservative treatment for CIN in England is 30 years, which is also the mean age of mothers giving birth in the UK. This review will address the current evidence and will summarise risks, potential mechanisms and current obstetric management of women previously treated for CIN, with an emphasis on UK-based practice. Conservative local treatment for CIN Excisional and ablative treatment techniques can be employed for the conservative local treatment of CIN. Both are simple and quick to perform, mostly under local anaesthesia in the outpatient clinic. Neither method has been shown to be superior with regard to recurrent CIN or invasive cancer (Martin-Hirsch et al., 2013). Large loop excision of the transformation zone (LLETZ) is the most commonly used technique in the UK, and involves a cone-shaped excision (Figure 1A) containing the whole transformation zone with the affected area of dysplastic cells. Immediate complications are relatively rare, infection and bleeding occurring in around 4 and 5% of cases, respectively (Sutthichon and Kietpeerakool, 2009). FIGURE 1. Site of cervical cone biopsy (A) and excised tissue (B)
A study on serum bilirubin levels in coronary artery disease patients

Background: The protective effect of bilirubin relates to the antioxidant property of bilirubin, which prevents lipid oxidation, especially low-density lipoprotein (LDL), and inhibits free radical-induced dam-ages. Lower serum bilirubin level has been proven to be associated with endothelium and microvascular malfunction. The aim of the present study was to assess the association between serum bilirubin levels and coronary artery disease in comparison with controls without coronary artery disease. Methods: A cross-sectional study was conducted for a period of a one year in our medical college hospital. Patients with evidence of coronary artery disease for not more than 10 years of duration confirmed by ECG, ECHO and other previous case records were taken as cases. Controls were selected matched with age, gender and other co-morbid conditions. Total of 200 subjects were included in the study with 100 cases and 100 controls. General and systemic examination was conducted on all study subjects including laboratory investigations like complete blood count, renal function test, lipid profile, viral markers such as HBsAG, HCVIgM and liver function test which includes total bilirubin, direct and indirect, liver enzymes, albumin and globulin levels. A 12 lead ECG and a transthoracic echocardiogram was performed for all patients. Results: The various liver function test parameters were compared between the cases and controls it was found that the serum bilirubin levels which includes total bilirubin, direct bilirubin and indirect bilirubin was found to be lower among the case group compared to the control group and this difference was found to be statistically significant (p <0.05). A perfect linear correlation between the ejection fraction and serum bilirubin levels, as the ejection fraction decreases the serum bilirubin levels was also decreasing. Conclusions: This study showed a significant association between the reduced serum bilirubin levels and the occurrence of CAD; therefore, bilirubin level can serve as a predictive factor, together with other influential factors for identifying a person at risk of developing coronary artery disease.
Weed management strategies in maize (Zea mays): Effect on weed dynamics, productivity and economics of the maize- wheat (Triticum aestivum) cropping system in Indo-gangetic plains

A field experiment was conducted to evaluate the efficacy of different herbicidal treatments along with cowpea (Vigna unguiculata (L.) Walp. ) as live mulch crop as one of the treatments in preceeding maize (Zea mays L.) and their residual effects on succeeding wheat (Triticum aestivum L.) crop during 2010-11 and 2011-12. In maize field, metribuzin/atrazine was not found effective to control Dactyloctenium colonum, however, application of metribuzin 0.25 kg/ha as pre emergence (PE) followed by one hand weeding at 21 DAS was found most effective in controlling this weed. Metribuzin 0.25 kg/ha as PE + one hand weeding (HW) and maize + cowpea intercropping resulted in significantly lowest weed index which remained at par with atrazine as PE + one HW. However, after pooled analysis of results significantly highest grain yield (6 785 kg/ha) of maize was obtained with two HW, while highest grain yield of succeeding wheat (6 191 kg/ha) was obtained with the preceding effect of maize + cowpea. The highest pooled system productivity as maize equivalent yield (14 136 kg/ha) was obtained with maize + cowpea treatment which remained at par with application of atrazine or metribuzin as PE plus one HW. Significantly highest pooled gross (Rupees 153 864/ha), net (Rupees 101 948/ha) returns and B:C ratio (1.96) were also obtained with maize + cowpea, which remained at par with other tested weed management practices. The results indicate that inclusion of cowpea as cover crop in maize-wheat system will not only increase the profitability but also provide environment friendly option against the use of herbicides for weed management.
Phytoaccumulation and Bioextraction Potentials of Chrysopogon zizanioides L. Roberty in the Bioattenuation of Hydrocarbon Polluted Soils

Phytoaccumulation and bioextraction potentials of Chrysopogon zizanioides during bioattenuation of hydrocarbon contaminated soils was studied to assess accumulation and partitioning of Total Petroleum Hydrocarbon (TPH) and insoluble asphaltene in the plant tissues. Experimental design was Split-Split Plot (3 x 4 x 2). Main plot factors were crude oil contamination (3 levels), sub-Plot factors were soil amendments (4 levels), sub-sub-Plot factors were plant tissues (2 levels). Results indicated highly significant differences (P ≤ 0.01) in phytoaccumulation and bioextraction between plant tissues, crude oil contamination and soil amendments. Roots and turf of the grass were found to accumulate both TPH (0.52 g g -1 and 0.18 g g -1 respectively) and asphaltene (0.40 g g -1 and 0.11 g g -1 respectively). Bioaccumulation factor (BAF) for TPH was highest in C2 under treatment T4 (2.28 g g -1 and 2.13 g g -1 respectively) while asphaltene was highest in C2 not differing with C4 (2.87 g g -1 and 2.64 g g -1 respectively) under treatment T2 with 3.45 g g -1 . The plant was observed to phytoextract and accumulated 20.32 g g -1 TPH under C3 and 16.65 g g -1 asphaltene under C4 in three months. The best soil amendment for bioextraction and phytoaccumulation was T4 but T2 encouraged growth. Therefore, C. zizanioides was recommended as efficient hypper accumulator species for crude oil remediation. Phytomining from the plant could be considered.
Clinicopathological Correlation of Leiomyoma in a Tertiary Care Centre: A Retrospective Study

Leiomyoma is the most common type of benign tumor of uterus and carry 70-80% of cumulative incidence in reproductive age group. Our study was conducted to analyse the clinicopathological correlation, spectrum of variants and secondary changes of leiomyoma of uterus. The clinical presentation, histological pattern and combination with other reproductive tract lesions were also studied. The time period was two years from September 2016 to August 2018. A total of 100 hysterectomy and myomectomy specimens received in pathology department of T.S. Misra Medical College, were included in the study. Most of the patients of leiomyoma were present in their reproductive age. Hyaline change and calcification are commonly seen in longstanding leiomyomas and are clinically asymptomatic. In our study the incidence remains highest in the child bearing age group. Intramural leiomyoma was present in highest number. The presence of proliferative phase of endomentrium, endometrial hyperplasia, adenomyosis and cystic ovaries indicated association of leiomyoma with high estrogen levels in the blood. Introduction Leiomyoma is the most common type of benign tumor of uterus and carry 70-80% of cumulative incidence in reproductive age group. These tumors are rarely seen before puberty and regresses after menopause indicating definite correlation with estrogen level. It is also called fibroid due to abundance of fibrotic tissue. (1,2) Most cases of leiomyoma are asymptomatic and need no treatment. Among symptomatic cases, menstrual disturbances are the most common symptom and leads to anaemia in majority of patients. Other common symptoms are abdominopelvic pain and pressure symptoms. Pressure symptoms are urinary frequency and urgency which may develop due to large size fibroid or www.jmscr. igmpublication.org Impact Factor (SJIF): 6.379 Index Copernicus Value: 79.54 ISSN (e)-2347-176x ISSN (p) 2455-0450 DOI: https://dx.doi. org/10.18535/jmscr/v6i10.34
antifungal and antibacterial potentiality of six essential oils extracted from plant source.

In vitro evaluation of six essential oils viz., Allium sativum, Capsicum annum Cassia fistula, Coriandrum sativum, Cuminum cyminum and Curcuma longa were tested against ten seed borne fungi of paddy viz., Pyricularia oryzae, Bipolaris oryzae, Alternaria alternata, Tricoconis padwickii, Drechslera tetramera, Drechslera halodes, Curvularia lunata, Fusarium moniliforme, F. oxysprorum and F. solani and five human pathogenic bacteria viz., Escherichia coli, Pseudomonas aeruginosa, Salmonella typhi ,Vibrio cholera and Streptococcus pneumonia at 500,1000,1500 and 2000 ppm concentration. Among the six essential oils, A. sativum recorded a complete inhibition in eight fungi compared to control. A. sativum is followed by C. sativum , C. longa and C. cyminum . No significant activity was observed in C. annum and C. fistula against all the test fungi. In antibacterial assay, A. sativum recorded a maximum inhibition of all test bacteria in the range of 10.9 to36.9 mm, followed by C. longa (5.6 -25.6 mm), C. cyminum (10.9-30.2 mm). Least inhibition was observed in Capsicum annum and no antibacterial activity was observed in C. fistula.
COMPARATIVE ANALYSIS OF INCOME AND POVERTY STATUS OF WOMEN IN KOKORO (CORN SNACK) PRODUCTION AND ARABLE CROPS PRODUCTION IN OGUN STATE, NIGERIA

The study analyzed the poverty status of women producing Kokoro (Corn snack) and women producing arable crops in Ogun State, Nigeria. A total of 208 respondents made up of 106 women producing Kokoro (Corn snack) and 102 women producing arable crops to serve as control group were selected. The respondents were selected based on non- probability method. Purposive sampling technique with Snowball method was used. Data were obtained by structured interview schedule. Data collected were analysed using FGT poverty index, costs and return and t-test statistics. The results indicated that 34.9kg of maize were processed into 128 dozens of Kokoro (Corn snack) per production run over an average of five (5) days, with six (6) production runs per month for nine months for the period of the research. The mean Kokoro (Corn snack) production cost was N42, 769.41/ respondent/ month with average revenue of N92, 253.60/ respondent/ month and net income of N49, 484.19/ respondent/ month. Income from Kokoro (Corn snack) production accounted for 53.4% of the total household income of N721,323.67 of an average woman engaged in Kokoro (Corn snack) production while farm income accounted for 67.9% of the total household income of N418, 935.10 of an average woman producing arable crops. The study also revealed that households of Kokoro (Corn snack) producers had mean per capita household income of N282.32 per person per day which was significantly higher (p<0.01) than those of women producing arable crops, N191.29 per person per day. Thus Kokoro (Corn snack) production has the potentials to enhance income and reduce poverty among households of rural women. The study thus recommends promotion of value- adding activities, such as maize processing into Kokoro as a means of enhancing income and reduces poverty among the rural folks.
Generating Cyan Fluorescent Protein (CFP) From Green Fluorescent Protein (GFPUV) By Y66w Mutation

: This work seeks to generate CFP from GFPuv by Y66W mutation. Specific objectives include site directed mutagenesis on GFPuv and sequence alignment of generated CFP with wild type GFPuv and fluorimetry studies of CFP in relation to GFPuv. Several approaches that include plasmid digestion and GFPuv ligation, colony PCR,super-competent cell transformation, sequencing, sequence alignment, Ni-NTA chromatographic purification and fluorimetry were employed. Results show that GFPuv was successfully mutated to CFP as indicated on position 65 – 67 of aligned sequence thus, a clear confirmation that Y66W mutation in GFPuv generates CFP. Fluorimetry report 22.5nm difference in peak fluorescence between the proteins implying there was a stock shift.
Factors Influencing Inter-Pregnancy Interval among Antenatal Attendee in a Tertiary Hospital in Abakaliki, South-East, Nigeria

Background: World over, there has being an improvement in birth spacing resulting in a reduction in the perinatal and maternal morbidity and mortality rates. Objective: To appraise the factors influencing inter-pregnancy interval (IPI) among pregnant women receiving antenatal care at Federal Teaching Hospital Abakaliki. Methods: A descriptive cross-sectional study was done among antenatal attendee, with at least one previous delivery, in Federal Teaching Hospital, Abakaliki over a six month period using a structured questionnaire. Data obtained was analysed using IBM SPSS Statistics version 20. Results: The mean age of the respondents was 28.6 (95% CI 28.1 - 29.1) years. The majority (231, 70%) were multiparous. Most respondent (162, 49.1%) had their last delivery 6 - 12 months prior to conception. The significant determinants of IPI include: maternal age, marital status, place of residence, social class, baby’s sex, family income, use of contraceptive, parity and outcome of her last confinement. Contraceptive knowledge is high (300, 90.9%); more than 50% had the desire to use some form of contraceptive but majority (132, 40%) said they will never use contraceptive after delivery. Conclusions: Majority of the women had an IPI of 6 - 12 months. The major determinant of this includes having a live birth in last delivery, parity, marital status, and place of residence. The attitude to contraception is poor; effort needs to be directed into identifying the immediate and remote causes of this as this will help in proper education and counselling needed to increase contraceptive uptake.
Waste Tire Management: Lebanon Case Study

The industrial era has carried improvements to the quality of living human. With the rise of the industrial revolution, a noticeable transition occurred where machines and factories emerged, which helped in manufacturing merchandises. This was followed by the introduction of different waste materials, resulting from the manufacturing process, which are deleterious to our lives and environment. These wastes included tires. The problem of scrap tire became controversial in the late 1970s [1]. With the rise of the automotive industry during the mid of the 19th century, tire production gained attention. Manufacturers produced tires in the location where these tires were utilized, and when the life of tire is over, these tire wastes were stocked, resulting in public health, environmental and aesthetic problems. For example, one of the major fire hazards recorded in history was in 1999 when a tire dump in Westley, California burned for 36 days after being accidentally ignited by lightning which caused pyrolytic oil to flow and contaminate nearby streams and water bodies [2].
Robust Speech Dereverberation With a Neural Network-Based Post-Filter That Exploits Multi-Conditional Training of Binaural Cues

This study presents an algorithm for binaural speech dereverberation based on the supervised learning of short-term binaural cues. The proposed system combined a delay-and-sum beamformer with a neural network-based post-filter that attenuated reverberant components in individual time-frequency units. A multi-conditional training procedure was used to simulate the uncertainties of short-term binaural cues in response to room reverberation by mixing the direct part of head related impulse responses (HRIRs) with diffuse noise. Despite being trained with only anechoic HRIRs, the proposed dereverberation algorithm was tested in a variety of reverberant environments and achieved considerable improvements relative to a coherence-based approach in terms of three objective metrics reflecting speech quality and speech intelligibility. Moreover, a systematic evaluation showed that the proposed system generalized very well to a wide range of acoustic conditions, including various measured binaural room impulse responses reflecting different reverberation times, azimuth positions spanning the entire frontal hemifield, various source-receiver distances as well as different artificial heads.
AN EMPIRICAL STUDY ON THE IMPACT OF DIGITAL MARKETING ON PURCHASE INTENTION AMONG TEENAGERS IN MADURAI CITY

This study assesses the impact of digital marketing on teenagers’ purchase intention in Madurai city. The aim of the study is to find out the effectiveness of digital marketing and its effect on online buying decision of teenagers. The exploratory research design was adopted for the study. The data was collected from both primary and secondary data sources. Primary data was collected through structured scheduled questionnaire method. The secondary data was collected from related articles, journals, thesis, books, newspapers and internet, etc. The target population of the study consists of teenagers prefer to purchase through online in Madurai city. The sample size of the study consists of 100 customers chosen by purposive sampling technique. To analyze the data, the study applied statistical tools like descriptive, chi-square test, linear regression analysis andFriedman test. Based on the analysis, the study found that that there is a significant impact of digital marketing on purchase intention among teenagers of Madurai city. It is also identified that social media marketing is the preferable digital marketing channel of teenagers to take online purchase decision.
Transformations of television consumption practices: An analysis on documentary viewing among post-millennials

The adaptation of new infrastructure in the media industry, as well as the evolution of Web 2.0 and beyond, has decisively altered the ways of producing and consuming audiovisual content. The forthcoming generation of viewers are the post-millennials who have been born and raised within a digital world with completely different consumption patterns when compared to the previous generations. This comparative study aims to explore and assess the transformations of audiovisual consumption practices within the current digital environment. Specifically, the research focuses on examining audiovisual consumption patterns on documentary viewing utilizing focus group method; Greece and Cyprus were selected as case study locations, due to their interconnected culture and origins. The results are presented in a dual level; initially the ways post-millennials of Greece and Cyprus consume web & traditional documentaries are examined. Moreover, the patterns of audiovisual content consumption, comparing to previous generations, are explored. Volume 16, Issue 2 November 2019 Page 69
Evaluation of quality of life among patients referring for kyphoplasty due to vertebral fractures

Received 19.05. 2017 Revised 25.06. 2017 Accepted 26.08. 2017 Published 01.10. 2017 Background & Aim: Quality of life (QOL) is one of the important health components, indicating physical, social, and mental health. Vertebral fracture causes acute and chronic low back pain (LBP), physical disability and decreased QOL, and kyphoplasty is one of the effective methods for treating these types of fractures .
Pattern of substance abuse: a community based study in West Bengal

Background: Drug addiction produces serious pervasive and expensive social problems. Regardless of whether substance abuse is a sin, a crime, a bad habit or an illness society has a right to expect that an effective approach to drug abuse problem will reduce drug related crime unemployment, family dysfunction and disproportionate use of medical care. Science has made great progress over the past several years, but it is still not possible to account fully the physiological and psychological process that transform controlled voluntary use of drugs into uncontrolled is voluntary dependence on those substances, and these is still no cine. The objective of the study was to find out pattern of different types of substance abuse in a community in West Bengal.Methods: An observational cross-sectional community based study during April 2017-September 2017 in a community of West Bengal among 142 addicted persons.Results: In the studied 142 cases, Brown sugar (an adulterated form of Heroin) was primary drug of abuse in urban area contrary to alcohol in rural area. Commonest age of initiation was between 15-20 years (57.75%). Polydrug abusers (59.1%) were common.Conclusions: Our study revealed that in spite of having strict legislation for prohibition of substance abuse, people are still addicted with alcohol, cannabis, drugs etc. Substance use is prevalent in the studied area, with a higher prevalence in males. Substance users rarely seek treatment for substance use. This needs continuous awareness and community-level services for the treatment of substance use disorders.