Miracle-dz/UniFAR-FTUs huggingface dataset:
Galaxy formation and physical bias

We have supplemented our code, which computes the evolution of the physical state of a representative piece of the universe to include, not only the dynamics of dark matter (with a standard PM code), and the hydrodynamics of the gaseous component (including detailed collisional and radiative processes), but also galaxy formation on a heuristic but plausible basis. If, within a cell the gas is Jeans' unstable, collapsing, and cooling rapidly, it is transformed to galaxy subunits, which are then followed with a collisionless code. After grouping them into galaxies, we estimate the relative distributions of galaxies and dark matter and the relative velocities of galaxies and dark matter. In a large scale CDM run of 80/h Mpc size with 8 x 10 exp 6 cells and dark matter particles, we find that physical bias b is on the 8/h Mpc scale is about 1.6 and increases towards smaller scales, and that velocity bias is about 0.8 on the same scale. The comparable HDM simulation is highly biased with b = 2.7 on the 8/h Mpc scale. Implications of these results are discussed in the light of the COBE observations which provide an accurate normalization for the initial power spectrum. CDM can be ruled out on the basis of too large a predicted small scale velocity dispersion at greater than 95 percent confidence level.
ETHNOGRAPHIC STUDY OF SONGKET WEAVERS IN SUKARARA VILLAGE

This article addresses the intersection between gender, ethnicity, work performance, and economic capital. It focuses on Sasak Muslim women who weave songkets and their economic capital in Sukarara Village, Central Lombok. This article using an ethnographic approach focused on economic capital of songket weaver. The behavior, attitudes, and personalities that are inherent in weavers in their daily operations are examined holistically and particularly through qualitative research. This study found that Sasak Muslim women who weave songket fabric in Sukarara are in good performance due to their ability to use time wisely and complete tasks quickly and effectively. They are economically capable based on a lack of consumer debt, their capacity in business, their possession of investments, their ability to manage business finances, and their mental readiness for monetary turbulence. In this framework, Sasak Muslim women’s economic capital in songket weaving is separated into three roles: as the center of the family, as vehicles for personal fulfillment, and as wives.
Fusing high-resolution SAR and optical imagery for improved urban land cover study and classification

The two objectives of this study are to compare the performances of different data fusion techniques for the enhancement of urban features and subsequently to improve urban land cover types classification using a refined Bayesian classification. For the data fusion, wavelet-based fusion, Brovey transform, Elhers fusion and principal component analysis are used and the results are compared. The refined Bayesian classification uses spatial thresholds defined from local knowledge and different features obtained through a feature derivation process. The result of the refined classification is compared with the results of a standard method and it demonstrates a higher accuracy. Overall, the research indicates that multi-source information can significantly improves the interpretation and classification of land cover types and the refined Bayesian classification is a powerful tool to increase the classification accuracy.
Single-Cell and CellChat Resolution Identifies Collecting Duct Cell Subsets and Their Communications with Adjacent Cells in PKD Kidneys

ADPKD is a genetic disorder with a molecular complexity that remains poorly understood. In this study, we sampled renal cells to construct a comprehensive and spatiotemporally resolved gene expression atlas in whole Pkd1 mutant polycystic mouse kidneys at single-cell resolution. We characterized cell diversity and identified novel collecting duct (CD) cell subtypes in cystic kidneys. We further found that CD cells appear to take different cell fate trajectories, and the first and the most important step might take place around day 14 in Pkd1 homozygous kidneys. After that day, increased numbers of CD cells showed highly proliferative and fibrotic characteristics, as detected in later-stage Pkd1 homozygous kidneys, both of which should contribute to cyst growth and renal fibrosis. With a newly developed modeling algorithm, called CellChat Explorer, we identify cell-to-cell communication networks mediated by the ligand receptor, such as MIF-CD44/CD74, in cystic kidneys, and confirm them via the expression patterns of ligands and receptors in four major cell types, which addresses the key question as to whether and how Pkd1 mutant renal epithelial cells affect their neighboring cells. The allele-specific gene expression profiles show that the secretion of cytokines by Pkd1 mutant epithelial cells may affect the gene expression profiles in recipient cells via epigenetic mechanisms, and vice versa. This study can be used to drive precision therapeutic targeting of ADPKD.
Model for the Coupled Evolution of Subsurface and Coronal Magnetic Fields in Solar Active Regions

According to Babcock's theory of the solar dynamo, bipolar active regions are Ω-shaped loops emerging from a toroidal field located near the base of the convection zone. In this paper, a mean field model for the evolution of a twisted Ω-loop is developed. The model describes the coupled evolution of the magnetic field in the convection zone and the corona after the loop has fully emerged into the solar atmosphere. Such a coupled evolution is required to fully understand what happens to the coronal and subsurface fields as magnetic flux cancels at polarity inversion lines on the photosphere. The jump conditions for the magnetic field at the photosphere are derived from the magnetic stress balance between the convection zone and corona. The model reproduces the observed spreading of active region magnetic flux over the solar surface. At polarity inversion lines, magnetic flux submerges below the photosphere, but the component of magnetic field along the inversion line cannot submerge, because the field in the upper convection zone is nearly radial. Therefore, magnetic shear builds up in the corona above the inversion line, which eventually leads to a loss of equilibrium of the coronal fields and the "lift-off" of a coronal flux rope. Fields that submerge are transported back to the base of the convection zone, leading to the repair of the toroidal flux rope. Following Martens and Zwaan, interactions between bipoles are also considered.
Evaluation of Blood Biochemistry and Cardiopulmonary status of Hospitalized Covid-19 Patients in 3 Months Post Discharged Follow up Survey

BACKGROUND The new coronavirus causes systemic inflammation and damage to various organs. So, this study aimed to follow up patients with COVID −19 after recovery for three months by performing cardiac, pulmonary and laboratory tests. MATERIALS AND METHODS This was a prospective cohort study of COVID-19 patients who were discharged from Baharloo Hospital. The diagnosis of COVID-19 was confirmed by PCR or long CT scan. Inclusion criteria were age over 18 years and patients with more than 50% of pulmonary involvement in lung CT scan. The patients were called to Baharloo hospital three months after recovery and were examined for cardiac, pulmonary and blood tests. RESULT Our study included 178 participants with mean age of 55.70, and 50.6% of them were male. Among pulmonary factors in the hospital, 71.9%, 15.7%,1.7%,19.1% and 53.4% had positive GGO, consolidation, reverse halo sign, traction bronchiectasis and vascular enlargement, respectively. After three months follow up, percentage of patients who had reticulation, honeycombing, fibrotic brand and bullae were 12%, 1.1%,8.4% and 0%, respectively. The Mean values of FVC and FEV1 were reported 4.21 and 3.01, respectively. Among Cardiac factors, positive PVC, PAC and mean Pap were decreased after three months. Only Growth in myalgia and Decreased sense of taste were statistically significant. Also, D dimer, UA protein, PMN, Ferritin CRP, PMN, LDH and HB amounts had decreased significantly. CONCLUSION Our study indicated that in addition to pulmonary changes, rapid damage to other organs and the occurrence of cardiac symptoms and changes in laboratory result were also reported in patients recovered from COVID-19.
Genome-wide analysis of cytochrome P450 genes in Citrus clementina and characterization of a CYP gene encoding flavonoid 3′-hydroxylase

Abstract Cytochrome P450s (CYPs) are the largest family of enzymes in plant and play multifarious roles in development and defense but the available information about the CYP superfamily in citrus is very limited. Here we provide a comprehensive genome-wide analysis of the CYP superfamily in Citrus clementina genome, identifying 301 CYP genes grouped into ten clans and 49 families. The characteristics of both gene structures and motif compositions strongly supported the reliability of the phylogenetic relationship. Duplication analysis indicated that tandem duplication was the major driving force of expansion for this superfamily. Promoter analysis revealed numerous cis-acting elements related to various responsiveness. RNA-seq data elucidated their expression patterns in citrus fruit peel both during development and in response to UV-B. Furthermore, we characterize a UV-B-induced CYP gene (Ciclev10019637m, designated CitF3′H) as a flavonoid 3′-hydroxylase for the first time. CitF3′H catalyzed numerous flavonoids and favored naringenin in yeast assays. Virus-induced silencing of CitF3′H in citrus seedlings significantly reduced the levels of 3′-hydroxylated flavonoids and their derivatives. These results together with the endoplasmic reticulum-localization of CitF3′H in plant suggest that this enzyme is responsible for the biosynthesis of 3′-hydroxylated flavonoids in citrus. Taken together, our findings provide extensive information about the CYP superfamily in citrus and contribute to further functional verification.
Population Genetics of Anopheles pretoriensis in Grande Comore Island

Simple Summary In this study, we assessed phylogenetics of 24 Anopheles species and the genetic structure of Anopheles pretoriensis populations on Grande Comore Island. Our study is the first to report the whole mitochondria genome of A. pretoriensis and the first to inform on the genetic relationship of this species’ populations, both within the island of Grande Comore and between the island and continental Africa. Studies on secondary vectors of malaria, such as A. pretoriensis, are significant because they have been reconsidered in regard to their role in sustaining malaria transmission after primary vectors are controlled. Abstract Anopheles pretoriensis is widely distributed across Africa, including on oceanic islands such as Grande Comore in the Comoros. This species is known to be mostly zoophylic and therefore considered to have low impact on the transmission of human malaria. However, A. pretoriensis has been found infected with Plasmodium, suggesting that it may be epidemiologically important. In the present study, we sequenced and assembled the complete mitogenome of A. pretoriensis and inferred its phylogenetic relationship among other species in the subgenus Cellia. We also investigated the genetic structure of A. pretoriensis populations on Grande Comore Island, and between this island population and sites in continental Africa, using partial sequence of the mitochondrial cytochrome c oxidase subunit I (COI) gene. Seven haplotypes were found on the island, one of which was ubiquitous. There was no clear divergence between island haplotypes and those found on the continent. The present work contributes knowledge on this understudied, yet abundant, Anopheles species.
The role of subjective well-being in serious leisure and active aging: Evidence from older Chinese Tai Chi participants

As leisure awareness has improved, increasing numbers of older adults have begun to participate seriously in leisure activities to experience greater happiness and enhance their quality of life. This study examined the mediating role of subjective well-being in serious leisure and active aging (AA) among older Tai Chi (TC) participants. We proposed a model mediated by subjective well-being and validated this model using stepwise regression and bootstrapping methods. Data were collected from 286 older adults who engaged seriously in TC in Hangzhou, China. The results showed that (a) subjective well-being partially mediates the relationship between serious leisure and AA; (b) subjective well-being partially mediates the relationships between serious leisure and the four subdimensions of AA; (c) among the four subdimensions, the mediating effect of subjective well-being on the relationship between serious leisure and interpersonal support and the direct effect of serious leisure on body vitality are relatively large. These results help explain the intricate relationship between serious leisure and AA among older TC participants and have theoretical and practical implications for those who are interested in the phenomenon of aging.
Rotational mirror–mirror entanglement via dissipative atomic reservoir in a double-Laguerre–Gaussian-cavity system

We propose a new scheme to prepare macroscopic entanglement between two rotating mirrors using dissipative atomic reservoir in a double-Laguerre–Gaussian-cavity system. The two-level atomic system driven by a strong field, acts as a single pathway of Bogoliubov dissipation to push the two original cavity modes into the desirable entangled state under the near-resonant conditions. Successively, the photon–photon entanglement can be transferred to mirror–mirror entanglement through the exchange of orbital angular momentum. In essence, the macroscopic entanglement is originated from the dissipative atomic reservoir rather than the radiation torque, thereby it is usually robust against environmental noises. The present scheme provides a feasible way to realize stable entanglement between spatially separated mirrors with high capacity, which may find potential applications in remote quantum communications.
A Systematic Review of Electronic Medical Record Driven Quality Measurement and Feedback Systems

Historically, quality measurement analyses utilize manual chart abstraction from data collected primarily for administrative purposes. These methods are resource-intensive, time-delayed, and often lack clinical relevance. Electronic Medical Records (EMRs) have increased data availability and opportunities for quality measurement. However, little is known about the effectiveness of Measurement Feedback Systems (MFSs) in utilizing EMR data. This study explores the effectiveness and characteristics of EMR-enabled MFSs in tertiary care. The search strategy guided by the PICO Framework was executed in four databases. Two reviewers screened abstracts and manuscripts. Data on effect and intervention characteristics were extracted using a tailored version of the Cochrane EPOC abstraction tool. Due to study heterogeneity, a narrative synthesis was conducted and reported according to PRISMA guidelines. A total of 14 unique MFS studies were extracted and synthesized, of which 12 had positive effects on outcomes. Findings indicate that quality measurement using EMR data is feasible in certain contexts and successful MFSs often incorporated electronic feedback methods, supported by clinical leadership and action planning. EMR-enabled MFSs have the potential to reduce the burden of data collection for quality measurement but further research is needed to evaluate EMR-enabled MFSs to translate and scale findings to broader implementation contexts.
Examining Cadets’ Beliefs about Meditation Using the Reasoned Action Approach

Meditation has been shown to be a character and virtue formation tool due to its emotion regulation capabilities. Training academies can help their students better develop their character by enabling meditation behavior acquisition. This study examines United States Military cadets’ beliefs about meditation as a means of informing education and intervention programming to maximize the likelihood of cadets adopting the behavior. Implications and suggestions for character education programs are provided.
Physicochemical and Mechanical Properties of Premixed Calcium Silicate and Resin Sealers

The aim of the present in vitro study was to evaluate specific mechanical and physicochemical properties of two calcium silicate based sealers, (AH Plus Bioceramic “AHPB”; Well-Root ST “WRST”), and a conventional resin sealer (AH Plus “AHP”). These aims were accomplished by assessing the porosity, pH, compression strength, roughness, wettability and cell attachment of the tested materials. The results were compared statistically using the one-way ANOVA test. Higher pH values were obtained in both AHPB and WRST compared to AHP at 3, 24 and 72 h (p < 0.05). A greater level of porosity and wettability was detected for both AHPB and WRST compared to the resin sealer AHP (p < 0.05). Evident cell growth characterized by elongated morphology was observed on the surface of AHPB and WRST, while only a thin layer of cells was seen on the surface of AHP. A significant lower compression strength and modulus were obtained in the specimens created using AHPB compared to those made with AHP and WRST (p < 0.05). The removal of calcium silicates may be quite tricky during endodontic retreatment. In conclusion, considering the limitations of the present in vitro study, both calcium silicate sealers demonstrated good physicochemical properties. However, the lower compression strength and modulus of AHPB may facilitate its removal and make the retreatment procedures considerably easier.
Diallyl Trisulfide Suppresses the Renal Cancer Stem-like Cell Properties via Nanog

Abstract Cancer stem-like cells (CSCs), which play an important role in tumor initiation and progression, have been identified in many cancers. Diallyl trisulfide (DATS) is an organosulfur compound extracted from garlic with anticancer activities. Nanog is a transcription factor responsible for maintaining the stemness of CSCs, but its role in the DATS-induced attenuation of renal CSC properties is unknown. In this study, renal CSCs were enriched from human renal cancer cell lines 786-O and ACHN cultured in a serum-free medium (SFM). The properties of CSCs were analyzed by evaluating the ability of the cells in sphere formation and measuring the expression of stem cell markers. We found that downregulation of Nanog inhibited renal CSC properties. DATS suppressed renal CSC activities by reducing tumorsphere formation, decreasing stem cell markers including Nanog, CD44, ALDH1A1, and Oct4, inhibiting cell proliferation and promoting apoptosis. We further revealed that overexpression of Nanog reversed the suppressive effects of DATS on renal CSCs. Taken together, our results demonstrated that DATS inhibited renal CSCs by suppressing Nanog. These novel findings suggested that, through Nanog targeting, DATS can potentially be used as an anti-tumor agent for renal cancer.
Multiwavelength observations of cirrus clouds in the North Celestial Loop: a study of the OH emission

New 1665- and 1667-MHz OH observations were made with the Green Bank Telescope at an angular resolution of 7 arcmin of 108 locations over two diffuse gas clouds at high Galactic latitude. A linear correlation is observed between the IRAS 100 μm infrared intensity, which traces all the gas, and the OH column density, indicating that the amount of OH increases with the visual extinction above a threshold value of Av ≈ 0.5. N(OH) increases monotonically with N(H I) in up to N(OH) ≈ 0.25-0.3 x 10 14 cm -2 . At greater values of N(OH) the H I column density saturates at N(H I) ≈ 5 x 10 20 cm -2 , suggesting that there is molecular gas not traced by H I. No correlation is found between the 12 CO integrated intensity and the OH column density, indicating that OH might be a better tracer of H 2 than CO in those diffuse regions. An H I column density of at least ≈2.2-2.9 x 10 20 cm -2 is needed for the formation of OH, but in regions where the cloud is less shielded from the interstellar radiation field the value rises to N(H I) = 3.3 x 10 20 cm -2 .
Serum extracellular vesicle‐derived ASS1 is a promising predictor for the occurrence of HEV‐ALF

Development of biomarkers for predicting the occurrence of hepatitis E virus related‐acute liver failure (HEV‐ALF) is conducive to prevention and early intervention. Serum samples from 250 HEV‐ALF patients, 250 patients with acute hepatitis E (AHE) and 250 health controls (HCs) were collected. We assessed the predictive ability of extracellular vesicle (EV)‐derived argininosuccinate synthase 1 (ASS1) levels for HEV‐ALF occurrence. Serum EVs were successfully isolated. EV‐derived ASS1 levels in the HEV‐ALF patients were significantly higher than those in the AHE patients and HCs. In HEV‐ALF patients, EV‐derived ASS1 levels were positively correlated with the number of failed organs and disease progression. The logistical regression showed that EV‐derived ASS1 level is an independent risk factor for HEV‐ALF, and orthogonal partial least squares discriminant analysis (OPLS‐DA) also suggested that EV‐derived ASS1 level has high predictive capability. Besides, the area under the curve (AUC) of EV‐derived ASS1 level to predict HEV‐ALF occurrence was 0.728 (0.684–0.772) with the sensitivity and specificity being 72.80% and 64.80%, which had a high decision‐making ability. Furthermore, there existed no significant difference between the age ≥60 and age <60 groups in EV‐derived ASS1 levels. Serum EV‐derived ASS1 level is a promising predictor for the occurrence of HEV‐ALF.
Clinical and Epidemiologic Features of Viral Gastroenteritis in Hospitalized Children: An 11-Year Surveillance in Palermo (Sicily)

In order to acquire information regarding viral agents and epidemiologic features of severe paediatric Viral Acute Gastroenteritis (VAGE) across multiple seasons in the pre-rotavirus-vaccine era, the epidemiologic characteristics of VAGE were investigated among paediatric patients hospitalized in a major Sicilian paediatric hospital from 2003 to 2013. Overall, 4725 children were observed and 2355 (49.8%) were diagnosed with a viral infection: 1448 (30.6%) were found positive to rotavirus, 645 (13.7%) to norovirus, 216 (4.6%) to adenovirus, and 46 (0.97%) to astrovirus. Viral infections showed different patterns of hospitalization in terms of age at risk (younger for rotavirus and adenovirus infections), seasonality (increased risk in winter for rotavirus and norovirus), trend over time (reduced risk in 2011–2013 for norovirus and rotavirus) and major diagnostic categories (digestive diseases more frequent in adenovirus and astrovirus but not in norovirus). This study increases general knowledge of VAGE epidemiology and contributes to suggest some a priori diagnostic criteria that could help clinicians to identify and treat viral agents responsible for gastroenteritis in hospital settings.