Miracle-dz/UniFAR-FTUs huggingface dataset:
Large-eddy simulation of the high-Reynolds-number flow through a high-aspect-ratio cooling duct

We present well-resolved large-eddy-simulations (LES) of a straight, high-aspect-ratio cooling duct (HARCD) at a bulk Reynolds number of Re = 110 • 103 and an average Nusselt number of Nu = 371. The geometry and boundary conditions have been defined together with Rochlitz et al. (2015), who conducted the experimental measurements for this case. Water was chosen as coolant. The current investigation focuses on the influence of asymmetrical wall heating on the flow field and specifically on the influence of the turbulence-induced secondary flow on turbulent heat transfer, the spatial development of the temperature boundary layer and the accompanying viscosity modulation. Due to the viscosity drop in the vicinity of the heated wall we observe a decrease in turbulent length scales and in turbulence anisotropy, resulting in a decrease of turbulent mixing and the secondary flow strength along the duct.
New data on lichen flora of the Edough Peninsula in north-eastern Algeria

New information on the diversity of lichen flora of the Edough Peninsula in Algeria is presented and analysed. This study aimed to estimate the diversity of corticolous lichens on the rhytidome of Quercus suber L. in the district of Seraïdi, Annaba town, which is situated in north-eastern Algeria. During this study, nineteen species new to the Edough Peninsula were identified. Two species of the Pannariaceae family, Pectenia plumbea (Lightf.) P.M. Jørg, L. Lindblom, Wedin & S. Ekman and Fuscopannaria leucosticta (Tuck.) P.M. Jørg. , are rare in the region. Pectenia plumbea is a new species to the region, whereas Fuscopannaria leucosticta is new to the region and, after a long time, was rediscovered in Algeria.
Generation of frequency-tunable squeezed single photons from a single quantum dot

We demonstrate the generation of frequency-tunable squeezed single photons from a continuous wave laser-driven single-quantum-dot system using a rigorous theoretical formalism, the so-called polaron master equation theory for accurately incorporating the exciton–phonon coupling. We investigate the squeezing for both resonant and off-resonant excitations and show that even for an appropriate off-resonant excitation, the degree of quadrature squeezing can be equal to or even greater than the maximum value obtained for a resonant excitation due to the increased purity of the quantum dot system. We further demonstrate, without losing the degree of squeezing, the tunability of the central frequency of squeezed photons by adjusting the detuning. We show that the detrimental effects due to the exciton–phonon coupling remain negligible up to the phonon bath temperature of 20 K and become quite appreciable beyond this temperature, particularly at higher phonon cutoff frequencies.
Explorations in the Conformal Bootstrap

We investigate properties of various conformally invariant quantum systems, especially from the point of view of the conformal bootstrap. First, we study twist line defects in three-dimensional conformal field theories. Numerical results from lattice simulations point to the existence of such conformal defect in the critical 3D Ising model. We show that this fact is supported by both epsilon expansion and the conformal bootstrap calculations. We find that our results are in a good agreement with the numerical data. We also make new predictions for operator dimensions and OPE coefficients from the bootstrap approach. In the process we derive universal bounds on one-dimensional conformal field theories and conformal line defects. Second, we analyze the constraints imposed by the conformal bootstrap for theories with four supercharges in spacetime dimension between 2 and 4.
Commercial equine production in New Zealand 4: welfare implications of the New Zealand production systems

From racehorses to family pets, equine production and management is primarily pasture-based in New Zealand. Pasture-based equine production systems largely re ﬂ ect the horse ’ s ecological niche and have a unique set of management and welfare challenges. This review examines the potential welfare issues related to the management of horses in New Zealand. The economic value of horses varies greatly depending on their usage, which covers a wide spectrum from pest species (e.g. feral horses) to production (e.g. racehorses) and companion animals (e.g. leisure and sport horses). The view of where the horse is positioned on this spectrum may cause differing welfare threats to horses, due to the economic considerations, which drive the majority of welfare and managementaldecisions.The organisation,management,racingandwastage metricsoftheThoroughbred racehorse industry are well documented, and the bene ﬁ ts of the pasture-based system have become evident through less stressful weaning practices and opportunity for early exercise (which has been associated with longer careers and fewer musculoskeletal injuries). Identi ﬁ cation of equine-welfare research priorities in New Zealand remains challenging, given the lack of vertical integration of many sectors of the equine industry resulting in fragmented and limited availability of data.
Delphi Method in Analyzing of Minimum Wage Setting in Indonesia: Formula vs. Negotiation Model

Many countries set their minimum wages based on two models, through negotiation or mathematical formulas. In Indonesia, the negotiation model has been used to determine the minimum wages since 2003. In 2015, the law introduced the simple formula model that was further revised in 2016 with additional variables. Using the Delphi method, this study aims to find experts’ consensus regarding whether the governance of the formula model is superior to that of the negotiation model in terms of transaction cost minimization. Using the transaction cost economics approach, the two governances were compared in their performance in facilitating the negotiation, coordination, and dispute prevention between employ-ers and workers. This study finds that most experts reached a consensus, claiming that the mathematical formula model is more efficient than the negotiation model. In addition, most of the experts argue that data from the Central Statistic Agency (BPS) and the elimination of the role of regional heads increase the efficiency of the formula model. However, no consensus was reached regarding whether the mathematical formula can outperform the negotiation model in minimizing the risk of future disputes.
Diuron degradation by a mixed culture of bacteria immobilized in rice straw

Diuron has been widely applied to control weeds causing serious environmental pollution. In the current study, the mixed culture of three bacterial isolates, Bacillus subtilis DU1, Acinetobacter baumannii DU, and Pseudomonas sp. DUK, was investigated for diuron degradation in a packed reactor and soil. The immobilization of the bacteria mixture in rice straw increased the degradation. The specific degradation rates of diuron by bacteria immobilized in rice straw in batch cultures increased from 0.38 ± 0.03 mg/L at the first cycle to 0.98 ± 0.10 mg/L at the fourth cycle. The degradation using the reactor was also carried out in a continuous operation. Moreover, the introduction of bacteria into soil increased diuron degradation. This study shows the potential of diuron degradation in the reactor and in soil using the mixed bacterial culture immobilized in rice straw.
Local Treatment of Hepatocellular Carcinoma with Oligometastases: A Systematic Review and Meta-Analysis

Simple Summary Oligometastasis is defined as a malignancy disease characterized by a limited number of metastatic foci (3–5). In studies of lung cancer and prostate cancer, local treatment such as radiotherapy or surgery increased the prognosis of oligometastases. The efficacy of local treatment for oligometastasis of hepatocellular carcinoma is not well known. This meta-analysis reports that active local treatment of oligometastases in hepatocellular carcinoma significantly increased survival rates and improved survival outcomes. Abstract Although recent studies have shown favorable results after local treatment for oligometastases, the clinical decision of applying local treatment for oligometastatic hepatocellular carcinoma (HCC) remains controversial. This meta-analysis aimed to investigate the benefits of local treatment for HCC oligometastases. Pubmed, Embase, Medline, and the Cochrane library were searched for studies until 1 May 2022. Clinical studies involving at least five cases of HCC oligometsatases treated with local modalities were included. The primary endpoint was overall survival (OS). The benefit of local treatment was assessed as the pooled odds ratio (OR) among comparative series, and the pooled OS percentile was calculated from all studies including patients treated with local treatment. Complications of grade ≥ 3 were assessed subjectively. A total of 10 studies involving 527 patients were included. Radiotherapy and radiofrequency ablation (RFA) were mainly performed (six and five studies) as local modalities treating oligometastases. Pooled OR of comparative series favored the use of local treatment (4.664, 95% confidence interval [CI]: 2.595–8.380, p < 0.001, I2: ~0.0%). Including all cohorts with patients who underwent local treatment, pooled rates of 1-year OS were 71.8% (95% CI: 59.0–81.9; I2 = 81.5%), and pooled 2-year OS were 43.3% (95% CI: 29.1–59.6; I2 = 85.4%). Except for temporal or pre-existing toxicities, grade ≤ 3 complications were reported less than 10% in most studies, although common toxicities include pneumothorax and hematologic deficiency after RFA and radiotherapy, respectively. Grade 5 toxicity has not yet been reported. This systematic review supports the application of local treatment for treating HCC oligometastases.
Identification of a Novel SSTR3 Full Agonist for the Treatment of Nonfunctioning Pituitary Adenomas

Simple Summary Therapy for nonfunctioning pituitary adenomas (NFPAs) is a significant unmet medical need since these adenomas are frequently invasive, are difficult to resect completely and often recur. NFPAs express high levels of somatostatin receptor 3 (SSTR3), and SSTR3 agonists could be a promising new treatment, but SSTR3 agonists with sufficient characterization to allow clinical testing are not available. We unexpectedly discovered that ITF2984, a molecule originally developed as a pan-SSTR agonist, is a full agonist of SSTR3 in in vitro assays. A similar full agonism was not observed with Pasireotide another pan-SSTR agonist approved for the treatment of Cushing’s disease. These unexpected findings prompted us to test ITF2984 in an in vivo model that recapitulates the human disease, where ITF2984 showed significant antitumor activity. ITF2984 has completed phase II clinical trials in acromegaly patients, is well tolerated and can be directly tested in NFPA patients, potentially providing a long-sought-after therapeutic option. Abstract Somatostatin receptor (SSTR) agonists have been extensively used for treating neuroendocrine tumors. Synthetic therapeutic agonists showing selectivity for SSTR2 (Octreotide) or for SSTR2 and SSTR5 (Pasireotide) have been approved for the treatment of patients with acromegaly and Cushing’s syndrome, as their pituitary tumors highly express SSTR2 or SSTR2/SSTR5, respectively. Nonfunctioning pituitary adenomas (NFPAs), which express high levels of SSTR3 and show only modest response to currently available SSTR agonists, are often invasive and cannot be completely resected, and therefore easily recur. The aim of the present study was the evaluation of ITF2984, a somatostatin analog and full SSTR3 agonist, as a new potential treatment for NFPAs. ITF2984 shows a 10-fold improved affinity for SSTR3 compared to Octreotide or Pasireotide. Molecular modeling and NMR studies indicated that the higher affinity for SSTR3 correlates with a higher stability of a distorted β-I turn in the cyclic peptide backbone. ITF2984 induces receptor internalization and phosphorylation, and triggers G-protein signaling at pharmacologically relevant concentrations. Furthermore, ITF2984 displays antitumor activity that is dependent on SSTR3 expression levels in the MENX (homozygous mutant) NFPA rat model, which closely recapitulates human disease. Therefore, ITF2984 may represent a novel therapeutic option for patients affected by NFPA.
The Analysis of Students’ Mathematical Thinking based on Their Mathematics Self-Concept

This research aims to describe the students’ mathematical thinking based on their mathematics self-concept. In addition, this study also aims to determine whether there are differences in mathematical thinking between students who have positive mathematics self-concept (MSC) with students who have negative MSC and to know how much influence MSC to the students’ mathematical thinking. There are four indicators of students’ mathematical thinking which is used in this study. First, Specializing, i.e. trying the problem by looking at the example, paying attention to a simple case. Second, Generalising, i.e. looking for patterns and relationships. Third, Conjecturing, i.e. predicting relationships and results. Fourth, Convincing, i.e. finding and communicating the reason why something is right. This research used a descriptive method. The population of this study is all senior high school students in Subang, West Java. Instruments in this research are the test of students' mathematical thinking and MSC questionnaire. Based on the finding of this research, generally, students who have positive MSC, have good mathematical thinking abilities. Mann-Whitney U test results showed that significantly there are differences in mathematical thinking between students who have positive MSC with students who have negative MSC. Variables of MSC give positive and big influence on the students’ mathematical thinking.
Linear and weakly nonlinear analysis of Rayleigh–Bénard convection of perfect gas with non-Oberbeck–Boussinesq effects

The influences of non-Oberbeck–Boussinesq (NOB) effects on flow instabilities and bifurcation characteristics of Rayleigh–Bénard convection are examined. The working fluid is air with reference Prandtl number $Pr=0.71$ and contained in two-dimensional rigid cavities of finite aspect ratios. The fluid flow is governed by the low-Mach-number equations, accounting for the NOB effects due to large temperature difference involving flow compressibility and variations of fluid viscosity and thermal conductivity with temperature. The intensity of NOB effects is measured by the dimensionless temperature differential $\unicode[STIX]{x1D716}$ . Linear stability analysis of the thermal conduction state is performed. An $\unicode[STIX]{x1D716}^{2}$ scaling of the leading-order corrections of critical Rayleigh number $Ra_{cr}$ and disturbance growth rate $\unicode[STIX]{x1D70E}$ due to NOB effects is identified, which is a consequence of an intrinsic symmetry of the system. The influences of weak NOB effects on flow instabilities are further studied by perturbation expansion of linear stability equations with regard to $\unicode[STIX]{x1D716}$ , and then the influence of aspect ratio $A$ is investigated in detail. NOB effects are found to enhance (weaken) flow stability in large (narrow) cavities. Detailed contributions of compressibility, viscosity and buoyancy actions on disturbance kinetic energy growth are identified quantitatively by energy analysis. Besides, a weakly nonlinear theory is developed based on centre-manifold reduction to investigate the NOB influences on bifurcation characteristics near convection onset, and amplitude equations are constructed for both codimension-one and -two cases. Rich bifurcation regimes are observed based on amplitude equations and also confirmed by direct numerical simulation. Weakly nonlinear analysis is useful for organizing and understanding these simulation results.
Is It Correct to Consider Caustic Ingestion as a Nonviolent Method of Suicide? A Retrospective Analysis and Psychological Considerations

Background: Suicide methods chosen by victims are particularly critical in suicide risk research. To differentiate suicide deaths, it is usual to categorize them as violent and nonviolent depending on the detrimental method chosen by the victims. Caustic ingestion, for example, is traditionally considered as a nonviolent suicide method. It results in severe consequences for the human body and it is associated with high levels of lethality. Methods: In this study, we retrospectively analyzed suicides that occurred between 1993 and 2021 in Milan (Italy) and that underwent autopsy. We compared a sample of 40 victims that ingested caustic substances with a sample of 460 victims of other chemical ingestion, and a sample of 3962 victims from violent suicide. Univariate analyses and univariate logistic regression models were performed. Suicides from caustic poisoning were significantly older, had a higher mean number of diseases and were more affected by psychiatric diseases compared to other chemical ingestion victims. By contrast, caustic suicides, compared to violent suicides, had a more balanced gender ratio, a higher mean number of diseases, were more affected by psychiatric diseases, had a higher rate of complex suicides (more than one modality), and had victims who died more frequently inside instead of outside. In logistic regression models, age was the only feature differentiating caustic from other chemical ingestion suicides while the features differentiating caustic from violent suicides were gender, mean number of diseases and suicide place. Conclusions: Suicides by caustic ingestion showed substantial differences compared to violent suicides, with a higher severe profile. However, some differences were reported comparing caustic ingestion to other chemical ingestion as well. Thus, we argue whether it is more appropriate to differentiate the suicidal ingestion of caustics from both violent and nonviolent suicide methods.
Reliability-Driven Local Community Search in Dynamic Networks

Community search over large dynamic graph has become an important research problem in modern complex networks, such as the online social network, collaboration network and biological networks. Network data in the time-varied environment has motivated several recent studies to identify the evolution of the communities. However, these studies mostly match communities of different snapshot or utilize the aggregation of the disjoint structural information and ignores the cohesion continuity. To fill this research gap, in this work, we propose a novel <inline-formula><tex-math notation="LaTeX">$(\theta,k)$</tex-math><alternatives><mml:math><mml:mrow><mml:mo>(</mml:mo><mml:mi>θ</mml:mi><mml:mo>,</mml:mo><mml:mi>k</mml:mi><mml:mo>)</mml:mo></mml:mrow></mml:math><inline-graphic xlink:href="li-ieq1-3290295.gif"/></alternatives></inline-formula>-core reliable community (CRC) and define the reliable community search problem which jointly considers member engagement, connection strength and cohesion continuity of the community in the dynamic network. We propose an online search algorithm based on eligible edge filtering and we further construct the Weighted Core Forest-Index (WCF-index) and develop efficient index-based querying algorithm with strong pruning properties. We also propose top-<inline-formula><tex-math notation="LaTeX">$l$</tex-math><alternatives><mml:math><mml:mi>l</mml:mi></mml:math><inline-graphic xlink:href="li-ieq2-3290295.gif"/></alternatives></inline-formula> reliable community search problem that couples query based distance to reduce the free rider effect in local community search and support flexible multiple query vertices. Extensive experiments are conducted to show the efficiency and effectiveness of the proposed algorithms.
Technology Acceptance Model to Unveil Factors Affecting E-Business Adoption: A Small and Medium Enterprise Perspective

: An E-Business platform is a vital tool that provides SMEs with a platform to turn their traditional business into an advanced business model. Due to the rapid development of the Internet, there has been an interest in how to encourage the owner or manager of SMEs in Sarawak. In particular, the purpose of this paper is to investigate SMEs’ behavioral intention of adopting an e-business platform to focus on the perceptions of the users in terms of usefulness, ease of use
Vertically resolved weak temperature gradient analysis of the Madden‐Julian Oscillation in SP‐CESM

The collective effects of convection can influence large‐scale circulations that, in turn, act to organize convective activity. Such scale interactions may play an important role in moisture‐convection feedbacks thought to be important to both convective aggregation and the Madden‐Julian Oscillation, yet such interactions are not fully understood. New diagnostics based on tropical weak temperature gradient (WTG) theory have begun to make this problem more tractable, and are leveraged in this study to analyze the relationship between various apparent heating processes and large‐scale vertical moisture advection in SP‐CESM. WTG theory provides a framework for accurately diagnosing intraseasonal variations in large‐scale vertical motion from apparent heating, allowing large‐scale vertical moisture advection to be decomposed into contributions from microphysical processes, subgrid scale eddy fluxes, and radiative heating. This approach is consistent with the column moist static energy (MSE) budget approach, and has the added benefit of allowing the vertical advection term of the column MSE budget to be quantitatively partitioned into contributions from the aforementioned apparent heating processes. This decomposition is used to show that the MJO is an instability strongly supported by radiative feedbacks and damped by horizontal advection, consistent with the findings of previous studies. Periods of low, moderate, and high MJO amplitude are compared, and it is shown that changes in the vertical structure of apparent heating do not play a dominant role in limiting the amplitude of the MJO in SP‐CESM. Finally, a diagnostic approach to scale analysis of tropical dynamics is used to investigate how the governing dynamics of various phenomena differ throughout wavenumber‐frequency space. Findings support previous studies that suggest the governing dynamics of the MJO differ from those of strongly divergent convectively coupled equatorial waves.
Molecular characterization of multidrug-resistant avian pathogenic Escherichia coli isolated from poultry and poultry products

Overall occurrence of Escherichia coli in the current study was 7.55% and corresponding group wise occurrence was 13%, 2.66%, 10% and 7% in a faecal and cloacal samples, environmental samples, Retailer’s shop’s samples, and restaurant samples respectively. Amongst the different type of samples processed, highest recovery was from samples collected at poultry farms (13%) followed by Retailer’s shop (10%) suggesting heavy infection and contamination occurring at the initial points of poultry chain. In this study, four isolates failed to exhibit pathogenic potential of E. coli by using in - vitro pathogenic assays viz. Congo red dye binding assay and haemolysis by using 5% sheep blood agar, also turned out to be negative on virulent marker based PCR, suggesting proficient efficacy of targeted genes viz. ecp and uidA for precise and time saving determination of pathogenic potential of E. coli isolates. Besides, one isolate recovered from raw chicken meat sample showed resistance against all 15 antibiotics and other two isolates recovered from litter samples showed resistance against 14 antibiotics suggesting development of multi-drug resistance in common food pathogens, against the most widely used and effective drug of choices in animal as well as human medicine.