Miracle-dz/UniFAR-FTUs huggingface dataset:
Decoding visual network‐related dynamic functional connectivity for eyes‐open and eyes‐closed using machine learning

Eyes‐open (EO) and eyes‐closed (EC) are the two experimental conditions during resting state functional magnetic resonance imaging (fMRI) scan sessions. However, the dynamic neural mechanisms of EO/EC based on intrinsic connectivity networks (ICNs) remains largely unexplored. This paper aimed to decode the dynamic internetwork neural mechanisms for EO/EC using data mining and to identify EO/EC resting state fMRI scans based on machine learning. To achieve these goals, the two states were analyzed using the discriminative models, resulting in total accuracy of 85.87%, a sensitivity of 91.3%, and a specificity of 80.43%. In addition, the discriminative features discovered using data mining were related to previous findings. In summary, we applied visual network‐related inter‐ICN features to decode the neural mechanisms of EO/EC. The reproducible results suggested that visual network‐related inter‐ICN dynamic features could be beneficial for decoding visual attentions, and had potential as neuroimaging‐markers to identify EO/EC resting state fMRI scans.
Umbilical cord albumin and serum bilirubin as predictive factors for hyperbilirubinemia in term neonates

Background: Hyperbilirubinemia is one of the common causes of neonatal admission. As clinical evaluation may cause a delay in identification and subsequent initiation of medical therapy, there is a need for the sensitive and inexpensive predictive marker for hyperbilirubinemia in neonates. Measurement of cord albumin and its correlation with the serum bilirubin is one of the noninvasive predictive markers for Hyperbilirubinemia. The present study carried out to know the significance of umbilical cord albumin level as a predictor of neonatal hyperbilirubinemia.Methods: It is a hospital-based prospective cohort study, total 100 healthy term new-borns admitted in the Neonatal Intensive Care Unit, were included in the study as per study protocol over a period of one year. The blood sample was collected from umbilical cord blood for the analysis of bilirubin and albumin, and post 72 hours of life venous blood obtained for estimation of serum bilirubin and albumin along with direct and indirect Coombs test.Results: In this study most of the patients were in the gestational age of 37-38 weeks (71%) followed by 38-40 weeks (27%) and only 1% are >40 weeks. A positive correlation was observed between cord blood bilirubin, serum bilirubin, serum albumin, and cord blood albumin levels. Cord blood albumin was a better marker for neonatal hyperbilirubinemia with a sensitivity of 83%, and a specificity of 48%; as compared to cord blood bilirubin with a sensitivity and specificity of 73% and 39% respectively.Conclusions: From this study, cord blood albumin level was demonstrated as a good predictive marker for neonatal hyperbilirubinemia with a sensitivity of 83.1%. and specificity 48.8%. Hence, cord blood albumin may be used as a non-invasive predictor for neonatal hyperbilirubinemia.
Isoprenoid Quinone Composition of the Genus Microbacterium and Related Strains

Coryneform bacteria classification in Bergy’s Manual of Bacteriology [1] accommodate different genera as Cellumonas, Arthrobacter, Corynebacterium and Microbacterium described as incertea sedis. Other motile plant pathogens were added to coryneform group [2,3]. Numerical phonetic studies improved classification of coryneform [4,5]. Other markers were used to improve taxonomic position of coryneform bacteria such as DNA base composition determination [4,6-10], wall analysis [11-15] and mycolic acid analysis [2,15,16]. The use of additional marker (isoprenoid quinone) was recommended by [16,17] to improve classification of coryneform and related taxa. The analysis of the isoprenoid quinone of coryneform bacteria has been a useful aid to establish the taxonomic relatedness of bacterial strains [2, 3,17-20]. These quinines can be divided into menaquinones and ubiquinones abbreviation of their data is given in (Figure1a). Substantial investigation amongst coryneform have been carried out on the distribution of quinines bearing isoprenoid side chain. Bacterial quinones of this type can be sub-divided into menaquinones (2 methyl-3-polyisoprenyl 1-1,44 naphthoquinones and ubiquinones (co-enzyme Q; 12,3-dimethoxy-5-methyl-1-6polyprenyl-1-1,4 benzoquinone (Figure1b). The menaquinones (related to vitamin K) show structural variation at C-2 and ,more especially, at C-3.Variation at C-3 include the length and degree of un-saturation of the polyprenyl side-chain [22] and the presence of hydroxyl [21] and epoxide groups [22]. Similarly, ubiquinones show variation principally in the structure of polyprenyl sidechain [23]. Therefore, the structure of these compound might be of great value in classification of coryneform and related bacteria [23]. Other studies demonstrated that organisms can be clustered based on the isoprenoid side chain of the menaquinones [2,3,20,24,25]. From their analysis Minnikin et al [22] concluded that MK_8(H2) was the major menaquinones of the animal associate corynebacterium. Microbacterium flavum, with consistently shows affinities with the animal associated corynebacteria in numerical phonetic studies, also contains MK-8(H2). They also reported that Micro bacterium ammoniaphilum contained MK-9(H2). Isoprenoid quinines are membrane-bound compounds (lipid molecules) found in nearly all living organisms. It marked structural variation depending upon the microbial taxon [27-30]. Therefore, organisms can be clustered based on isoprenoid side chain of their menaquinones. and hence differentiation between various taxa could be improved [3,17,18,27]. *Corresponding author: Moh’d Nizar Battikhi, 1017-1645 De Maisonneuve O, Montreal H3H 2N3, QC, Canada. Received Date: June 12, 2019 Published Date: July 12, 2019 ISSN: 2687-8410 DOI: 10.33552/ACCS.2019. 01.000518
Lipid profile in anemia: Is there any correlation?

Objective: The objective of this study was to compare the pattern of lipid profile among subjects with or without anemia. Methods: All proven cases of anemia (hemoglobin <13 g% in men and <12 g% in women), irrespective of the causes, were included as cases. The controls were age- and sex-matched population without anemia. Patients with underlying diseases/medication that could affect either lipid profile or anemia were excluded from the study. The data collected include demographics and laboratory investigations such as complete hemogram, random blood sugar, serum creatinine, liver function tests, serum ferritin, serum iron, and fasting lipid profile. Results: A total of 200 participants were included in the study, which includes 100 cases and 100 controls. The mean cholesterol in patients with anemia is 122.47 ± 29.32 mg/dl, whereas in controls is 160.43 ± 38.91 mg/dl. The mean serum triglyceride level in patients with anemia was 89.41 ± 33.1532 mg/dl and in control group was 111.45 ± 40.6632 mg/dl. Mean high-density lipoprotein levels were 36.13 ± 12.8132 mg/dl in anemic patients and 45 ± 13.032 mg/dl in control group, whereas low-density lipoprotein (LDL) cholesterol level was 70.12 ± 21.64 mg/dl in the anemic group and 100.45 ± 30.8032 mg/dl in control group. Very LDL levels were higher in control group (21.96 ± 8.132 mg/dl) compared to the anemic group (18.34 ± 7.6432 mg/dl). The differences between two groups with regard to all lipoprotein levels were statistically significant; all the values being lower in anemic patients. Conclusion: Lipoproteins levels were significantly lower in anemic patients compared to nonanemic patients, and the reduction was proportionate to the severity of anemia. Type of anemia did not have any effect on lipid profile.
Obstetrics ICU admissions: challenges faced at a tertiary referral centre

Management of critically ill patients in obstetrics is a challenge owing to the changed physiology and unpredictability of the disease behaviour. Admission of obstetric patients occurs at approximately 0.1-0.9% of the total deliveries. Overall maternal death rate in the ICU varies from 3.4-21%. Delay in diagnosing the illness and infrequent admission of the obstetric patients to ICU, results in high morbidity and mortality. Intensive care is appropriate for patients in need of advanced respiratory support and who require support of two or more organ systems. In patients with chronic impairment of one or more organ systems who also have superadded acute failure of other organs, ICU care has shown to improve prognosis. Early referral to ICU is extremely important. If referral is delayed until the patient’s life is clearly at risk, the chances of full recovery are jeopardised. Stratification strategy for early admission to obstetric ICU is imperative to reduce maternal morbidity and mortality. Studies done from different parts of India have demonstrated different rates of utilisation of ICU for imparting care. Analysis of obstetric ICU admission gives an insight into the pattern of the attributable causes of critical illness prevalent in obstetric population of that area. ICU utilisation serves as an objective marker for the quality of care in that area. Such an effort is equally important for early identification of end stage organ failure to ensure appropriate intervention
Comparison of PUVA and UVB therapy in moderate plaque psoriasis

Background Ultraviolet light (UV) is one of the standard psoriasis treatments and has good effects for the majority of psoriatics, whether it comes from the sun or from UVB cabinets. It also suppresses the immune system of the skin and helps create vitamin D. Objective: The aim of the study was to evaluate the efficacy of UVB and PUVA therapy in moderate plaque psoriasis. Patients and Methods A total of fifty patients of either sex with multiple large plaque psoriasis, aged more than 30 years and having disease of more than one year duration, were included in the study. They neither had received any phototherapy, nor were they taking any systemic treatment during last one year. Patients were randomly divided in two equal groups of twenty five each. Group-I was given 12, thrice weekly sessions of PUVA treatment, while similar number of treatments of UVB was provided to group-II patients. To access the efficacy, Psoriasis area severity index (PASI score) was recorded at baseline, after 12 sessions of treatments and after one month follow up. Results were analyzed by using software program ‘Instat” and statistical significance was found out by analysis of variance test (ANOVA) and student “t” test. Results Both the groups showed significant improvement after 12 sessions of the treatments (p 0.05). But by comparing over all improvements in two groups, no statistically significant difference was found (p>0.05). Conclusion Both PUVA and UVB phototherapy are effective in moderate plaque psoriasis. However, UVB phototherapy having lesser short term adverse reactions, should be the first choice phototherapy (where facilities exist).
Long-term surveillance of Escherichia coli antibiotic resistance patterns in urinary tract infections in a southern India hospital

Background and Objectives: Urinary tract infections (UTIs) are commonly seen in clinical practice and are most often caused by Escherichia coli (E. coli). To administer appropriate antibiotic therapy and reduce morbidity, it is crucial to know the local resistance patterns of E. coli. This study aims to show long-term changes in the resistance of E. coli to commonly used antibiotics over the past two decades in a hospital in southern India. Materials and Methods: This study was carried out at Dr. Jeyasekharan Medical Trust, a multispeciality teaching hospital in southern Tamil Nadu. It analyzed data from records of all urine samples received, cultured, and tested for resistance in its microbiology laboratory between 1991 and 2012. Results: A total of 44% of the urine cultures grew organisms. E. coli was present in 73% of the positive cultures. A trend of increasing resistance to gentamicin, fluoroquinolones, and cephalosporins was noted over the study period. The development of resistance was faster with the fluoroquinolones and cephalosporins than gentamicin. Chloramphenicol resistance showed a downward trend. Amikacin and nitrofurantoin were the most effective antibiotics with 10% and 28% resistance levels, respectively, over the period that they were used. The levels of resistance to second-line antibiotics did not show any definite trend. Interpretation and Conclusions: This study shows changing patterns of E. coli resistance over a period within an institution. Monitoring urinary cultures and resistance patterns regularly can assist in developing guidelines for selecting appropriate first guess antibiotics, thereby optimizing patient outcome.
Impact of Political Connection Strength on the Internationalization Outcome of Chinese Firms: Perspectives from Market Exploration and Technology Acquisition

Although the role of a home country’s government in firms’ internationalization processes has been investigated, there is a gap in the literature concerning the effectiveness of the government’s effort. Based on the data of 1996 Chinese listed firms, this study investigates how the strength of Chinese firms’ political connection with their home country government impacts the outcomes of their internationalization activities. These activities are classified into market exploration and technology acquisition. We establish an index to measure the firms’ political connection strength and find that it exhibits a bimodal distribution, which indicates that some firms maintain a close relationship with the government, while the business activities of others are distant from the government. The strength of the political connection has different moderating effects on firms’ internationalization processes when either the international market context or the firms’ internationalization activities vary. A strong political connection is beneficial for firms to explore the markets and acquire beneficial technology from developed countries. Compared with its role in exploring international markets, political connection plays a more significant moderating role in augmenting the positive effect of international technology acquisition on firms’ innovation capability. Therefore, Chinese firms may perform better in the internationalization process if they maintain a close relationship with the Chinese government, which engages in promoting the internationalization of domestic firms through an array of policies that may compensate for the firms’ disadvantages. Our results show the mechanism through which emerging countries’ governments use directives and incentives to facilitate the internationalization of domestic firms.
Measuring Emissions from the On-Road Vehicle Fleet in West Los Angeles

A sixteen-year record of on-road emission measurements at a West Los Angeles site (La Brea Ave. and I-10) was continued with an additional data collection campaign in May of 2018. During this campaign, the University of Denver collected 19,259 emission measurements of carbon monoxide (CO), carbon dioxide, hydrocarbons (HC), nitric oxide (NO), ammonia (NH3) and nitrogen dioxide (NO2) from light and medium-duty vehicles. Since 1999 the CO mean emissions have decreased by 84% (70.3 to 11 g/kg), the HC mean emissions by 79% (7.0 to 1.5 g/kg) and the NO mean emissions by 76% (6.6 to 1.6 g/kg). These decreases have happened despite an older fleet (8.9 years) now than prior to the 2008 recession. Over this same time, the 99 percentiles have dropped by more than a factor of three for CO and HC (773 to 212 gCO/kg of fuel and 93 to 31 gHC/kg of fuel) and a factor of 1.6 for NO (53 to 32 gNO/kg of fuel). However, during recent campaigns, the reductions in the 99 percentiles have leveled out for HC and may be slowing for CO, which will likely slow future emissions reductions despite gradual electrification of the fleet.
Management Strategies on an Upland Soil for Improving Soil Properties

ABSTRACT Upland soils marginal in organic matter, low in soil quality, vulnerable to water and nutrient losses. This study was conducted to determine whether the integration of winter cover crops and soil amendments into no-till cropping systems improve upland soil quality. The effects of winter cover crops (WCCs), broiler litter (BL) and flue gas desulfurization (FGD) gypsum in no-till (NT) corn-soybean rotation on soil physical and biological properties were investigated at Pontotoc, MS on an upland Falkner silt loam soil (fine-silty, siliceous, active, thermic Aquic Paleudalfs). After harvest, soil samples were collected and analyzed for total C (TC) and selected physical and biological properties. Averaged across fertilization treatments, WCCs increased TC, cumulative infiltration and reduced bulk density (BD) and penetration resistance (PR) at 0–5 cm depth as compared to winter fallow (WF). Averaged across WCCs treatments, BL increased infiltration by 51%, and reduced BD and PR by 3% and 24%, respectively, as compared to unfertilized control. Co-application of FGD gypsum with BL reduced BD and PR at 5 cm soil depth by 4% and 5%, respectively. Interestingly, BL did not affect soil microbiological parameters, but the co-application of FGD gypsum with BL resulted in a significant response in soil dehydrogenase activity. On the other hand, cover crop increased ureC (urease C) genes, probably due to conserved soil moisture by cover crop residues. Integration of WCCs, organic and inorganic amendments into no-till corn-soybean appear to improve soil physical, hydrological and microbial properties, which may enhance the efficiency of cropping systems in upland soils.
Adaptive Market Hypothesis

Purpose: To investigate the implications of the Addaptive Market Hypothesis (AMH) on Turkish stock exchange market (Borsa Istanbul) indices as an emerging economy. BIST-100, BIST-30 and BIST-All indices are subjected to the analyses for the period between January 2002 and April 2017. Design/Methodology/Approach: Two-year rolling windows and daily test values were calculated by using linear methods (Variance Ratio Test) and nonlinear methods (BDS test) to investigate the market efficiency. Findings: According to the Variance Ratio Test results, index returns are unpredictable, that is, the market is efficient, while the results of nonlinear analysis show the existence of adaptive market hypothesis. In particular, all three indices display efficiency in the 2013-2016 period implying that returns were not predictable in this period. The results of the non-linear analysis show that the market is efficient from time to time and sometimes deviates from efficiency, indicating the validity of the adaptive market hypothesis in Borsa Istanbul. Practical Implications: The changes in the market efficiency from time to time should be considered while taking important investment decisions. Moreover, according to AMH, since trends, panics, bubbles and crashes exist in the market, arbitrage opportunities arise time to time, and market timing is an important issue to catch the profit opportunities. Therefore, as a further study, matching the important events with the efficiency of the market could provide more insights about timing the market. Originality/Value: To the best of authors’ knowledge, this is the first comprehensive study that examines the index based AMH in Borsa Istanbul. This study is believed to contribute to the literature by giving insights about the evolution of market efficiency in Turkey.
Flexibility and Authority: Resolving Labor Disputes in A County Government in Western China

Existing literature regards ﬂexibility and authority as key characteristics of informal justice. We further contend that the combination of the two is crucial for informal justice to be effective. We investigate the process of dispute resolution by a Chinese labor agency. Following the life cycles of a sample of 810 labor disputes, we ﬁnd that this informal justice forum was efﬁcient and effective, made possible by the combination of ﬂexibility and authority. Flexibility means that the agency attracts certain types of cases that are usually screened out of the formal legal system and that agency ofﬁcials use “informal,” hence ﬂexible, techniques. Authority means that the administrative agency possesses additional powers over the disputants; hence, the dis-putants are under pressure to follow its suggestions and decisions. A comparative analysis of various cases of informal justice reinforces the importance of combining ﬂexibility and authority. We further demonstrate that ﬂexibility without authority is insufﬁcient and that some informal justice forums are effective because they enjoy both.
Modelling scour and deposition in harbours due to complex tsunami‐induced currents

In this paper, a set of models responsible for hydrodynamics, sediment transport, and morphological evolution are introduced with their theoretical backgrounds, and it is explained how they are fully connected through a two‐way coupling to yield an integrated sediment transport model applicable to tsunami cases. In particular, a fully nonlinear Boussinesq model with bottom shear‐induced rotational terms is chosen for the hydrodynamic model in order to provide a better physical approximation of tsunami‐related, near‐bed hydrodynamics in the nearshore. A finite‐volume scheme, stable and suitable for phase‐resolving model runs longer than 10 simulated hours, is adopted in the numerical discretization. The accuracy and applicability of the developed model are investigated through numerical tests on various sediment problems in the shallow region. Calculated results agree well with existing experimental records. Finally, an ocean‐wide, field‐scale simulation of the 2011 Tohoku‐oki tsunami is attempted, with a focus on the localized effects of tsunami‐induced morphological changes at Crescent City Harbor and Santa Cruz Harbor (USA). Consistent with the reported observations, strong and vortical velocity fields are generated through the model and result in significant changes in morphological configurations. Depth variations and areas of scouring and deposition are compared between modelled and observed records, and the results are discussed. © 2019 John Wiley & Sons, Ltd.
Faded Bedtime Intervention for Delayed Sleep Onset in an Adolescent With Autism Spectrum Disorder

We report the case of an 18-year-old girl who had autism spectrum disorder (ASD) and demonstrated persistent delayed sleep onset after going to bed in her group home at a residential school. Intervention consisted of a faded bedtime in which her customary time to bed was extended later into the night, then gradually made earlier as she started falling asleep more rapidly over the course of many weeks. By conclusion of the study and at a 1-month follow-up, the girl was falling asleep in less than 30 min after going to bed and sleeping an average of 8.4 hr each night. Compared with previous research with children in inpatient and home environments, the study found positive effects from a faded bedtime intervention without additional procedures, targeted an adolescent with ASD, and was conducted by care providers in a novel residence setting.
Liver Assessment in Patients with Osteoarthritis Taking Non Steroidal Anti Inflammatory Drugs Mainly (Diclofenac Acid) Within Two to Six Weeks of Treatment

INTRODUCTION: Drug induced liver injury encompasses a spectrum of clinical disorders ranging from mild biochemical abnormalities to acute liver failure (1) . Non steroidal anti-inflammatory drugs (NSAIDs) are frequently used and among the most common drugs associated with DILI (2) . DILI can be predominantly hepatocellular with rise in serum aminotransferases activity or cholestatic with predominant rise in serum alkaline phosphatase (ALP) activity or mixed injury in which both serum aminotransferases and ALP activity are elevated (1) . Cytochrome P450 is the most important family of