Miracle-dz/UniFAR-FTUs huggingface dataset:
Individual Radiation Protection Monitoring in the Marshall Islands: Enewetak Island Resettlement Support (May-December 2001)

The US Department of Energy (DOE) has recently implemented a series of strategic initiatives to address long-term radiological surveillance needs at former US test sites in the Marshall Islands. The plan is to engage local atoll communities in developing shared responsibilities for implementing radiation protection programs for resettled and resettling populations. Using pooled resources of the US Department of Energy and local atoll governments, individual radiation protection programs have been developed in whole-body counting and plutonium urinalysis to assess potential intakes of radionuclides from residual fallout contamination. The whole-body counting systems are operated and maintained by Marshallese technicians. Samples of urine are collected from resettlement workers and island residents under controlled conditions and analyzed for plutonium isotopes at the Lawrence Livermore National Laboratory using advanced accelerator based measurement technologies. This web site provides an overview of the methodologies, a full disclosure of the measurement data, and a yearly assessment of estimated radiation doses to resettlement workers and island residents.
Making Sense of ET Adjustment Factors for Budgeting and Managing Landscape Irrigation

Landscape water budgeting and conservation are central to many urban development programs and codes, water purveyor delivery and pricing policies, and professional landscape irrigation management practices. These programs, policies, and practitioners often use various approaches to calculate and establish a site's water-conserving irrigation budget and irrigation schedules based in part on estimated local reference evapotranspiration (ETo) data. These calculations can involve an assortment of ETo adjustment factors associated with plant species, site characteristics, or other influences on how much water a landscape requires or should be allocated. Depending on the formula used, the adjustments to ETo can be fixed, variable, or some combination. Science in landscape plant water requirements and plant ecology shows it is illogical to apply guesstimated user-selected ETo adjustment factors for microclimate and plant density or to use a species-specific plant factor (PF) to adjust ETo that are derived from non- scientific data bases. Rather, research shows that a distinct PF applies to each of the following plant type groups: turfgrass; trees, shrubs and groundcovers; annual flowers; herbaceous perennials; and desert plants. Except where there are microclimate influences that can be quantified scientifically to be significantly different from the location where ETo is calculated, a landscape water requirement can be simply yet effectively estimated by applying just the appropriate research-based plant-type PF's, such as follows: Gallons of Water = ETo (inches) × PF (fraction) × Landscape Area (square feet of plant type) × 0.62.
Artificial Intelligence and Lung Cancer: Impact on Improving Patient Outcomes

Simple Summary In this comprehensive review, we aimed to summarize the advances made by artificial intelligence in the field of lung cancer screening, diagnosis, and management. We now understand the utility of AI as a tool that can supplement physicians to improve the quality of care provided, which is the core message of this review, along with the relevant literature supporting the advances. Abstract Lung cancer remains one of the leading causes of cancer-related deaths worldwide, emphasizing the need for improved diagnostic and treatment approaches. In recent years, the emergence of artificial intelligence (AI) has sparked considerable interest in its potential role in lung cancer. This review aims to provide an overview of the current state of AI applications in lung cancer screening, diagnosis, and treatment. AI algorithms like machine learning, deep learning, and radiomics have shown remarkable capabilities in the detection and characterization of lung nodules, thereby aiding in accurate lung cancer screening and diagnosis. These systems can analyze various imaging modalities, such as low-dose CT scans, PET-CT imaging, and even chest radiographs, accurately identifying suspicious nodules and facilitating timely intervention. AI models have exhibited promise in utilizing biomarkers and tumor markers as supplementary screening tools, effectively enhancing the specificity and accuracy of early detection. These models can accurately distinguish between benign and malignant lung nodules, assisting radiologists in making more accurate and informed diagnostic decisions. Additionally, AI algorithms hold the potential to integrate multiple imaging modalities and clinical data, providing a more comprehensive diagnostic assessment. By utilizing high-quality data, including patient demographics, clinical history, and genetic profiles, AI models can predict treatment responses and guide the selection of optimal therapies. Notably, these models have shown considerable success in predicting the likelihood of response and recurrence following targeted therapies and optimizing radiation therapy for lung cancer patients. Implementing these AI tools in clinical practice can aid in the early diagnosis and timely management of lung cancer and potentially improve outcomes, including the mortality and morbidity of the patients.
Submarine Canyons: Multiple Causes and Long-Time Persistence

The actual investigation of submarine canyons as field work was begun about 50 years ago. A large amount of factual information has accumulated as result of operations of deep diving vehicles, first in the Pacific Coast canyons and more recently in the remarkable dives of the Woods Hole minisubmarine Alvin into East Coast canyons. Taking the results of these recent dives and combining them with earlier investigations, including much work done by the French in the Mediterranean as well as our extensive studies off California and Baja California, we can now say with some confidence that these amazing deep excavations into the sea floor off so many coastal areas can be explained. New methods such as side scanning have also given us a greater understanding of the exact character of submarine canyons, particularly in the Bay of Biscay. The development of multichannel sonar has greatly increased our knowledge of the nature of continental margins and hence their history. This has given us more insight into the history of canyon development, particularly off the east Coast where drilling for oil and gas has become so important. In the past we have seen a great variety of hypotheses for explaining submarine canyons. Unfortunately almost all of these have been based on information from a small selection of the canyons, usually from one area. From the new information, it is evident that canyons are of composite origin and that many of the hypotheses suggested in the past were partly correct but did not appreciate that coordination of other processes was required. Thus there is growing evidence that, in the history of many canyons, there was a period in which subaerial erosion was an important precursor, but that present features are predominantly the result of marine erosion. Those advocating turbidity currents as the unique cause of canyons failed to appreciate that debris flows down the incipient valleys, as ell as other types of landslides, could be an almost equally important factor in marine erosion. The great effect of biologic activity on the rock walls of incipient canyons has been almost completely neglected in explanations, and various types of currents such as those of the tides have been left largely out of the picture. Perhaps the most important feature absent in these various hypotheses has been the realization that canyons may well be the result of a long period of formation, much longer than the short episodes of Pleistocene glacial sea-level lowering features which commonly cut into hard crystalline rock. New information is showing that the canyons may date back to at least the Cretaceous.
Burial experiments with marine turtle carcasses and their paleoecological significance

Two carapaces of the hawksbill turtle (Eretmochelys imbricata) were buried in intertidal calcareous sands in a lagoonal setting of the Seychelles Islands (Indian Ocean). The taphonomic patterns are compared to similar ones from Upper Jurassic deposits of Central Europe
Quality and antioxidant activity of dandelion root infusions as affected by cold plasma pretreatment

Abstract Ground and unground dandelion roots were subjected to dielectric barrier discharge cold plasma (DBDCP) at 40 kV for 0 (control), 10, or 20 min. Then, infusions of the pretreated dandelion roots in water were prepared, and the changes in color, total phenolic content (TPC), antioxidant activity, and sensory properties were investigated. The 20‐min pretreatment increased the b* value, TPC, antioxidant activity, and sage odor of the ground dandelion root infusions compared with the control, whereas decreases in the TPC, antioxidant activity, and sage odor were noted in the 10‐min pretreated infusions of the unground roots. DBDCP pretreatment did not affect the overall likeliness of infusions of ground and unground roots. In addition, the TPC, antioxidant activity, and overall likeliness of infusions of the ground dandelion roots were higher than those of the unground samples. In conclusion, it can be said that the DBDCP pretreatment can be utilized to improve the TPC and antioxidant activity of ground dandelion roots.
Regeneration Therapy: The Role of Platelet-Rich Plasma in Post-hysterectomy Wound Dehiscence Healing

A 58-year-old (para 2, living 2, abortion 0), overweight (BMI: 25 kg/m2), post-hysterectomy patient reported with wound dehiscence on day seven. She was a known case of hypertension and type 2 diabetes for the last five years. She presented with symptoms of abnormal uterine bleeding due to leiomyoma. The leiomyoma was refractory to medical management and thus she underwent a total abdominal hysterectomy. She underwent the procedure well after preoperative intensive diabetes and hypertension management. She was managed postoperatively with injectable antibiotics. On day seven postoperatively, the patient started experiencing wound discharge, after which she was treated with broad spectrum higher antibiotics and regular wound dressing with debridement of necrotic debris twice daily for five days. She was planned for alternative therapy in the form of rejuvenation therapy by platelet-rich plasma therapy, which thus helped further shorten her hospital stay and helped the wound to heal better.
Therapeutic Effects of Mesenchymal Stromal Cells Require Mitochondrial Transfer and Quality Control

Due to their beneficial effects in an array of diseases, Mesenchymal Stromal Cells (MSCs) have been the focus of intense preclinical research and clinical implementation for decades. MSCs have multilineage differentiation capacity, support hematopoiesis, secrete pro-regenerative factors and exert immunoregulatory functions promoting homeostasis and the resolution of injury/inflammation. The main effects of MSCs include modulation of immune cells (macrophages, neutrophils, and lymphocytes), secretion of antimicrobial peptides, and transfer of mitochondria (Mt) to injured cells. These actions can be enhanced by priming (i.e., licensing) MSCs prior to exposure to deleterious microenvironments. Preclinical evidence suggests that MSCs can exert therapeutic effects in a variety of pathological states, including cardiac, respiratory, hepatic, renal, and neurological diseases. One of the key emerging beneficial actions of MSCs is the improvement of mitochondrial functions in the injured tissues by enhancing mitochondrial quality control (MQC). Recent advances in the understanding of cellular MQC, including mitochondrial biogenesis, mitophagy, fission, and fusion, helped uncover how MSCs enhance these processes. Specifically, MSCs have been suggested to regulate peroxisome proliferator-activated receptor-gamma coactivator 1 alpha (PGC1α)-dependent biogenesis, Parkin-dependent mitophagy, and Mitofusins (Mfn1/2) or Dynamin Related Protein-1 (Drp1)-mediated fission/fusion. In addition, previous studies also verified mitochondrial transfer from MSCs through tunneling nanotubes and via microvesicular transport. Combined, these effects improve mitochondrial functions, thereby contributing to the resolution of injury and inflammation. Thus, uncovering how MSCs affect MQC opens new therapeutic avenues for organ injury, and the transplantation of MSC-derived mitochondria to injured tissues might represent an attractive new therapeutic approach.
Gold Prices, World Oil Prices and Large Trade Price Index on Indonesian Sharia Stock Index with Exchange Value as A Moderating Variable in Indonesia

The aim of this study was to determine how much influence the Gold Price, World Oil Price and Wholesale Price Index have on the Indonesian Sharia Stock Index with the Exchange Rate as a Moderating Variable in Indonesia. This study uses a quantitative approach to secondary data with the MRA analysis method. The results of his research show that the price of gold has a positive and significant influence on the Indonesian Islamic Stock Index; World oil prices have a positive and significant impact on the Indonesian Islamic Stock Index; Wholesale Price Index has a negative and significant influence on the Indonesian Islamic Stock Index; The rupiah exchange rate moderates (strengthens) the relationship between the gold price and the Indonesian Sharia Stock Index; The rupiah exchange rate moderates (strengthens) the relationship between world oil prices and the Indonesian Sharia Stock Index; The rupiah exchange rate moderated (strengthened) the relationship between the Wholesale Price Index and the Indonesian Sharia Stock Index.
Identiﬁcation and Characterization of a Serum Protein Homologous to a -type Phospholipase A 2 Inhibitor (PLI a ) from a Nonvenomous Snake, Elaphe quadrivirgata

Summary From a liver cDNA library prepared from a nonvenomous striated snake, Elaphe quadrivirgata , we isolated a cDNA encoding a novel protein, PLI a -like protein (PLI a -LP), having approximately 70% sequence identities with the a -type phospholipase A 2 (PLA 2 ) inhibitors (PLI a s) previously puriﬁed from the venomous snakes Agkistrodon blomhoﬃi siniticus and Trimeresurus ﬂavoviridis . Since the PLI a -LP with a highly conserved C-type lectin-like domain (CTLD) would be predicted to function as a PLA 2 inhibitor, we puriﬁed this protein from E. quadrivirgata serum by sequential chromatography on Hi-trap Blue, Mono Q, and Superdex 200 columns. The puriﬁed 51-kDa protein with PLI a -like immunoreactivity was found to be a trimer of 18-kDa PLI a -LP, which was comparable to the trimeric structure of PLI a . But, unexpectedly, this protein did not show any inhibitory activity against various snake venom PLA 2 s. Furthermore, it did not inhibit the endogenous PLA 2 activities in various tissue homogenates prepared from this snake. Lack of the inhibitory activity in PLI a - LP may provide important information concerning the structure-function relationships of PLI a . IUBMB Life , 55: 539–545, 2003
Origin of high-An plagioclase in the early Permian (~280 Ma) Xiaohaizi wehrlite, Northwest China: insights from melt inclusions in clinopyroxene macrocrysts and zircon oxygen isotopes

ABSTRACT The Xiaohaizi wehrlite intrusion in the early Permian Tarim Large Igneous Province, Northwest China, is characterized by unusual high-An (up to 86) plagioclases. It has been suggested that H2O may have exerted a major control on their formation, but this interpretation requires further direct evidence. Moreover, it remains unclear where the water came from. In order to unravel these questions, we present electron microprobe analyses of minerals and melt inclusions in clinopyroxene macrocrysts in the dikes crosscutting the Xiaohaizi wehrlite intrusion and in situ oxygen isotope data of zircons from the Xiaohaizi wehrlite. The homogenized melt inclusions have restricted SiO2 (45.5–48.7 wt.%) and Na2O + K2O (2.4–3.8 wt.%) contents, displaying sub-alkaline affinity. This is inconsistent with the alkaline characteristic of the parental magma of the clinopyroxenes, suggesting significant modification of melt inclusions by contamination of the host clinopyroxene due to overheating. Nevertheless, the Ca/Na ratios (2.9–4.7) of melt inclusions are the upper limit of the parental magma of the clinopyroxenes due to high CaO (21.5–23.0 wt.%) and very low Na2O (0.22–0.34 wt.%) contents in the host clinopyroxenes. Thermodynamic calculation suggests that under fixed P (2.7 kbar) and T (1000°C), and assumed H2O (~1.5 wt.%) conditions, the Ca/Na ratio of the parental magma cannot generate high-An plagioclase in the wehrlite. The results confirm that H2O exerts a major control. Zircon δ18O (VSMOW) values (2.99–3.71‰) are significantly lower than that of mantle-derived zircon (5.3 ± 0.6‰). Such low zircon δ18O values may be due to incorporation of large amounts of low-δ18O, hydrothermally altered oceanic crust. However, geochemical and Sr-Nd-Pb isotopic data do not support recycled oceanic crust in the mantle source of the Xiaohaizi intrusion. Alternatively this can be explained by incorporation of meteoritic water in the magma chamber. This will increase the H2O content of the liquid that finally crystallize high-An plagioclases.
Risky Sexual Behaviour and Sexual Victimization among Young People with Risky Substance Use in Europe—Perspectives from Belgium, Sweden, the Czech Republic, and Germany

Background: Research indicates that among the risks associated with young people’s alcohol and illicit drug use are sexual risks. However, insights into co-occurrence of substance use and sexual risks in adolescent samples and possible differences across countries are limited. Methods: A sample of 1449 adolescents from Belgium, Sweden, the Czech Republic, and Germany screened positive for risky alcohol/illicit drug use in a web-based intervention against alcohol and illicit drug use. They also reported incidents of sex while being drunk and/or high on drugs, condomless sex on these occasions, and sexualized touching and sexual victimization while being drunk or high on drugs. Results: In the sample, 21.5% of the participants reported sexualized touching, 9.9% being victim to sexual assault, and 49.8% having had sex while being drunk and/or high on drugs; of the latter, 48.3% had condomless sex. Reports on having had sex while being drunk and/or high on drugs were associated with higher levels of past 30-day binge drinking. Being a victim of sexual assault was associated with past 30-day binge drinking only in young men. Conclusion: When devising preventive interventions against risky substance use in adolescents, an additional focus should be set on integrating steps against sexual risks.
An Examination of the Factors Affecting Residential PropertyValues in Magodo Neighbourhood, Lagos State

A B S T R A C T Lagos State is steadily emerging a multi-nuclei metropolis giving rise to a number of business hubs and real estate submarkets. Notwithstanding, investment and return on property are normally adjudged as more juicy in some neighbourhoods such as Ikoyi, Victoria Island, Lekki-axis, Ikeja, Apapa, Isale Eko and Amuwo Odofin. Obviously, these neighbourhoods share similar characteristics in that they are at the centre of Lagos State business activities, the home to many industrial establishments, headquarters of several business formations, the destination of early morning traffic rush from various parts of the State. The relationship among accessibility, property values and land use patterns has been the pre-occupation of earliest theorists with indication that travel costs were traded off against rents, population densities and distances from the Central Business District. This study assesses the veracity of this proposition in Magodo neighbourhood property market and the impact of other factors such as locational, structural and neighbourhood characteristics. A total of 232 questionnaires were distributed to two study groups, the estate surveyors and valuers and Magodo residents. Response were presented and analysed with tables, percentages and relative importance index. It was found amongst other things that travel distance and cost does not affect residential property value as others factors do. It was recommended that property investors should consider those attributes that significantly affect property values while government should endeavour to harness development potentials in the study area.
Complete blood and urine paraprotein tests as response assessments in multiple myeloma patients treated with bortezomib, cyclophosphamide, and dexamethasone

Abstract Background This study assessed the effect of standardized efficacy markers on prognosis in patients with newly diagnosed multiple myeloma (MM) during the induction phase of treatment with bortezomib, cyclophosphamide, and dexamethasone (BCD). Methods We retrospectively analyzed clinical data in 197 newly diagnosed MM patients treated with BCD as front‐line regimen at Peking Union Medical College Hospital from January 1, 2013 to December 31, 2018. Results There were 107 patients with International Staging System (ISS) III and 51 with paraprotein of light chain. Of these, 77 completed nine cycles of the BCD regimen. As the number of treatment cycles increased, the proportions of serum and urine immunofixation electrophoresis (IFE) tests elevated from 40.39% to 62.22% and 16.75% to 37.78%, respectively. More than 90% of intact immunoglobulin chain MM patients were evaluated for blood M protein per cycle, but that of urinary M protein was less than 60%. The detection rate of urinary M protein in light chain MM was more than 70% per cycle. Patients with a very good partial response (VGPR) had longer progression‐free survival (PFS) than those with uncertain VGPR (32 vs. 26 months, p = 0.0336). Of the 141 patients who completed at least four cycles without undergoing autologous hematopoietic stem cell transplantation, those who were regularly assessed at every other cycle showed more favorable PFS than those who visited irregularly (27 vs. 22 months, p = 0.059). Conclusion Urinary M protein detection rate is significantly lower than that in serum, leading to an overestimation of efficacy, premature reduction of treatment intensity, and shortened PFS. Precise response assessments are critical to treatment decisions and clinical diagnoses.
Artificial Neural Network Models of Daily Pan Evaporation

Artificial neural network (ANN) models are proposed as an alternative approach of evaporation estimation for Lake Egirdir. This study has three objectives: (1) to develop ANN models to estimate daily pan evaporation from measured meteorological data; (2) to compare the ANN models to the Penman model; and (3) to evaluate the potential of ANN models. Meteorological data from Lake Egirdir consisting of 490 daily records from 2001 to 2002 are used to develop the model for daily pan evaporation estimation. The measured meteorological variables include daily observations of air and water temperature, sunshine hours, solar radiation, air pressure, relative humidity, and wind speed. The results of the Penman method and ANN models are compared to pan evaporation values. The comparison shows that there is better agreement between the ANN estimations and measurements of daily pan evaporation than for other model.