Miracle-dz/UniFAR-FTUs huggingface dataset:
Factors Associated with Unscheduled Emergency Department Revisits in Children with Acute Lower Respiratory Tract Diseases

Purpose To identify factors associated with unscheduled emergency department (ED) revisits within 72 hours in children with acute dyspnea from lower respiratory tract diseases. Patients and Methods This retrospective cohort study included pediatric patients (age group: one month to 15 years old) who visited the ED with acute lower respiratory tract diseases between January 1st, 2017 and February 28th, 2019. The medical records were reviewed and discharged patients were dichotomized into revisit and non-revisit groups, based on whether the patients needed a revisit or not. Baseline characteristics, vital signs, diagnosis, treatment, pediatrician consultation, ED length of stay, and primary doctor of both groups were compared. Univariate and multivariate analyses by logistic regression were used to determine the significant factors associated with the revisits. Results Medical records of 918 eligible pediatric patients (1417 visits) were reviewed. Factors significantly associated with the revisits were history of asthma or current controller use (odds ratio [OR]: 3.08: 95% confidence interval [CI]: 1.86–5.1). Not prescribing systemic corticosteroids (P < 0.001), or prescribing them upon discharge without first dose in the ED (P = 0.022) were significantly associated with revisits. Conclusion No prescription of systemic corticosteroids or prescription upon discharge, without an immediate dose at the ED, in children with history of asthma or current controller use were associated with revisits.
Impact and Progression of Organ Dysfunction in Patients with Necrotizing Soft Tissue Infections: A Multicenter Study

Abstract Background: Necrotizing soft tissue infections (NSTI) represent a rare but devastating disease for which the systemic manifestations have been poorly characterized. In an effort to define an optimal endpoint for clinical trials in this condition, the objective of this study was to establish the pattern of organ dysfunction over time and determine the correlation between organ dysfunction and clinical outcome in patients with NSTI. Methods: We conducted a multicenter, retrospective clinical study of patients with NSTI presenting to 12 academic medical centers in the U.S. during 2013. Patients with a diagnosis of NSTI confirmed by surgical findings were included. Organ dysfunction was assessed using a modified Sequential Organ Failure Assessment (SOFA) score (mSOFA: excluding liver) on admission and on hospital days 1, 2, 3, 7, 10, and 14. The presence of organ dysfunction on admission and resolution of organ dysfunction were correlated with clinical parameters, including intensive care unit (ICU)-.
Distributed estimation with empirical likelihood

With the development of science and technology, massive datasets stored in multiple machines are increasingly prevalent. It is known that traditional statistical methods may be infeasible for analyzing large datasets owing to excessive computing time, memory limitations, communication costs, and privacy concerns. This article develops divide‐and‐conquer empirical likelihood (DEL) and divide‐and‐conquer exponentially tilted empirical likelihood (DETEL) methods for the distributed computing setting. We investigate the theoretical properties of the DEL and DETEL estimators. In particular, we derive upper bounds for the mean squared errors of the DEL and DETEL estimators, and, under some mild conditions, we prove the consistency and the asymptotic normality of the proposed estimators. Simulation studies and a real data analysis are carried out to demonstrate the finite‐sample performance of the proposed methods.
Silicon Mitigates Ammonium Toxicity in Cabbage (Brassica campestris L. ssp. pekinensis) ‘Ssamchu’

Ammonium (NH4+) toxicity hinders the cabbage yield because most subspecies or varieties exhibit extreme sensitivity to NH4+. Current knowledge indicates that silicon (Si) can alleviate or reverse the ammonium toxicity severity. However, few investigations have been conducted on NH4+-stressed cabbage to elucidate the mechanism underlying the Si alleviation. The study described herein analyzes induced physio-chemical changes to explore how Si helps mitigate NH4+ toxicity. We applied one of three NH4+:NO3- ratios (0:100, 50:50, and 100:0) at a constant N (13 meq·L−1) to the cabbage plants, corresponding with two Si treatment levels (0 and 1.0 meq·L−1). Chlorosis and foliage necrosis along with stunted roots occurred following 100% NH4+ application were ameliorated in the presence of Si. The NH4+ toxicity ratio was reduced accordingly. Similarly, inhibition on the uptake of K and Ca, restricted photosynthesis (chlorophyll, stomatal conductance, and Fv/Fm), and accumulation of reactive oxygen species (ROS, O2·-, and H2O2), as well as lipid peroxidation (MDA, malondialdehyde) in NH4+-stressed cabbages were mitigated with added Si. The lower observed oxidative stresses in solely NH4+-treated plants were conferred by the boosted antioxidant enzymes (SOD, superoxide dismutase; CAT, catalase). Concomitantly, Si-treated plants showed higher activities of key NH4+ assimilation enzymes (GS, glutamine synthetase; GOGAT, glutamate synthase; NADH-GDH, glutamate dehydrogenase) and NH4+ content in leaves. However, excessive NH4+ assimilations cause the acidic stress, which has been demonstrated to be the primary cause of NH4+ toxicity. Therefore, further investigation regarding the Si effects on H+ regulation and distribution should be warranted.
Psychometric Properties and Effects on Health Outcomes of the Patient Assessment of Chronic Illness Care (PACIC) in Korean Hemodialysis Patients

Background: The satisfaction of patients receiving integrated care with End-Stage Renal Disease (ESRD) is widely advocated and patients with ESRD have special health needs, but few studies have investigated whether integrated care was associated with health outcomes. Our aims were to evaluate the psychometric properties of the Korean-translated patient assessment of chronic illness care (PACIC) in patients with ESRD, and to evaluate whether PACIC evaluated by patients was associated with health outcomes. Methods: ESRD patients on hemodialysis (n = 172) at 2 dialysis centers. Data quality, internal consistency and correlation between items and scales were assessed. To test the external validity, the association between PACIC and the health behaviour and outcomes of hemodialysis patients was analyzed. Results: The mean score of the PACIC items was 3.0. The item-scale correlation (0.67–0.85) and test-retest correlation (0.72–0.82) regarding scales for internal consistency showed excellent consistency. Total PACIC score was significantly associated with dietary self-efficacy (β = 0.22) and serum potassium (Exp(B) = 1.65). Higher overall PACIC score was significantly associated with higher physical health status (β = 3.52). Conclusions: The Korean-translated PACIC questionnaire is a tool with reliability and validity. Comprehensive treatment strategies for ESRD patients may improve their health behaviors and outcomes.
Enhanced Glial Reaction and Altered Neuronal Nitric Oxide Synthase are Implicated in Attention Deficit Hyperactivity Disorder

Attention deficit hyperactivity disorder (ADHD) has a complex etiology, and its specific causal factors remain to be elucidated. Aberration of nitric oxide synthase (nNOS) and inflammation, together with astrocytic and microglial cells have been continually associated with several neurological disorders, including ADHD. Using spontaneously hypertensive rat (SHR), we investigated the changes in nNOS, inflammatory, microglial and astrocytic markers in the frontal cortex and hippocampus at three different ages: onset of hypertension stage (i.e., 6 weeks after birth of SHR), established hypertension stage (i.e., 12 weeks after birth of SHR) and senescent stage (i.e., 12 months after birth of SHR), and compared with its age-matched normotensive control, Wistar-Kyoto (WKY) rats. A significant upregulation of Iba-1 expression in the senescent stage of SHR was observed. Further, we observed an upregulated nNOS expression in both onset and established stages of SHR, and a downregulated nNOS in the senescent stage. Our study showed an age-related increment of astrogliosis in the cortex and hippocampi of aged SHR. On the basis of our results, alterations in the nNOS and Iba-1 expressions, as well as age-related astrogliosis, may contribute to ADHD pathogenesis.
Assessment of Communication Quality through Work Authorization between Dentists and Dental Technicians in Fixed and Removable Prosthodontics

Fabrication of a clinically successful dental prosthesis requires clear and effective communication between dentists and dental technicians. Adequate completion of work authorization by dentists provides a means for increased professional quality assurance and satisfaction in dental prosthesis. The aim of this study was to evaluate the quality of communication between dentists and dental technicians via work authorization for fixed and removable dental prosthesis in Pakistan. This cross-sectional study was conducted for a period of 6 months to assess the quality of communication between dentists and dental technicians. A well-constructed questionnaire regarding work authorization of removable and fixed prostheses was used as a tool to collect data from 453 dentists. A linear regression analysis was performed to evaluate the relationship of the independent and dependent variables. A p value of ≤0.05 was considered statistically significant. It was observed that 92.1% of the dentists leave removable partial denture design to the dental technicians. About 56.5% of the dentists indicated information about base retention of partial dentures in work authorization. The majority of the dentists (56.5%) mentioned the material to be used for the construction of casting partial dentures. Nearly 66% of the dentists indicated the design of margins, and 44.6% of the dentists did not select the shade for fixed prostheses. Nearly 43% of the dentists did not draw the design of restoration, 21.9% chose to draw the design on paper, and 32.2% of the dentists drew the design on the cast. Meanwhile, 76.8% of the participants chose to directly communicate with their dental technicians personally. Nearly 41% of the dentists were satisfied with the restoration design, and 13.5% of the participants were not satisfied with the designs. Poor communication between dentists and technicians was observed, as the majority of the design decisions were left to the dental technicians. Therefore, communication between dentists and dental technicians should be improved by conducting combined workshops for the successful construction of dental prostheses.
Understanding Differences in Behaviour Patterns of Healthcare Service Elements Among Regions Applying Data Mining

Maternal and child healthcare (MCH) has always been regarded as one of the important issues globally. The aim of this article is to find out all frequently occurring healthcare service elements along with their availability conditions and their interactions with other health system (HS) elements, when coverage of priority MCH intervention was either poor or moderate or good in any region. Association rule mining technique has been used to understand the probability of occurrences of different healthcare service elements among regions. Along with the proposed analytical framework, an interactive decision support system (DSS) has also been developed on a web platform, which would help healthcare policymakers to integrate the analytical framework easily in their processes of decision-making. The system has been developed by using Shiny package on R software. Data for all variables are collected for 584 Indian districts from the third phase of district-level household and facility survey. From results, it is observed that community healthcare services, sub-centre (SC)-level healthcare services and PHC-level healthcare services of a region are very much interlinked with each other, and their relationships define the healthcare condition of that region.
Eriodictyol Attenuates H2O2-Induced Oxidative Damage in Human Dermal Fibroblasts through Enhanced Capacity of Antioxidant Machinery

Oxidative stress in dermal fibroblasts is strongly correlated with the aging process of the skin. The application of natural compounds that can increase the ability of dermal fibroblasts to counteract oxidative stress is a promising approach to promote skin health and beauty. Eriodictyol is a flavonoid that exerts several pharmacological actions through its antioxidant properties. However, its protective effects on dermal fibroblasts have not yet been investigated. In this study, we investigated whether eriodictyol protects human dermal fibroblasts (BJ fibroblasts) from the harmful effects of hydrogen peroxide (H2O2). Eriodictyol pretreatment significantly prevented necrotic cell death caused by H2O2 exposure. In addition, the level of 2′,7′-dichloro-dihydro-fluorescein oxidation was decreased, and that of glutathione was maintained, indicating that the beneficial effects of eriodictyol against H2O2 were closely associated with oxidative-stress attenuation. Eriodictyol mediates its antioxidant effects on dermal fibroblasts against H2O2 through (i) the direct neutralization of reactive oxygen species; (ii) the enhancement of the activities of H2O2-detoxifying enzymes, including catalase and glutathione peroxidase; and (iii) the induction of the expressions of catalase and glutathione peroxidase 1 via the activation of the Nrf2 signaling system. These results support the potential application of eriodictyol as an ingredient in skincare products for cosmeceutical and pharmaceutical purposes.
Wavelength Measurements of Electron Cyclotron Harmonic Waves in Earth's Magnetotail

Electron cyclotron harmonic (ECH) waves, potential drivers for diffuse aurora precipitation, have been extensively investigated for decades. The generation mechanism of ECH waves, however, remains an open question. Theoretical work in 1970s has demonstrated that ECH waves can be excited by loss cone distributions of hot plasma sheet electrons. Recent THEMIS spacecraft observations, however, indicate that the waves can also be excited by low energy electron beams. Utilizing interferometry techniques to analyze the phase difference between electric potentials measured by individual probes on Electric Field Instrument antenna pairs on THEMIS spacecraft, we compute the wavenumber of both beam‐driven ECH waves and loss‐cone‐driven ECH waves. These wavenumber measurements as well as other wave properties obtained from spacecraft measurements prove to be consistent with expectation from linear instability analysis. This provides us with independent verification of the generation mechanism and linear dispersion relation of beam‐driven and loss‐cone‐driven ECH waves. Our statistical results demonstrate that the median value of the wave vectors of beam‐driven ECH waves, characterized by wave normal angles ( θB⇀,k⇀ $\theta \left(\stackrel{\rightharpoonup }{B},\stackrel{\rightharpoonup }{k}\right)$ ) less than 80°, is 0.011 m−1; and that of loss‐cone‐driven ECH waves, characterized by wave normal angles larger than 85°, is 0.00765 m−1. Direct wavenumber measurements of ECH waves allow us to better understand the interaction between ECH waves and electrons in Earth's magnetosphere.
COVID‐19, asylum seekers, and migrants on the Mexico–U.S. border: Creating states of exception

Abstract The COVID‐19 pandemic illuminates possibilities for creating states of exception while simultaneously destabilizing the Mexico–U.S. border through the politics of fear. Specifically, the Migrant Protection Protocols (MPP), Zero Tolerance Policy (ZTP), COVID‐19 CAPIO, Asylum Cooperative Agreements (ACA), and Title 42—using the pandemic under an arcane section of U.S. law to immediately expel asylum seekers and refugees, in particular—highlight the formation of a state of exception consistent with the work of Agamben. They also document how the politics of fear is used to reinforce hegemonic narratives targeting asylum seekers while attempting to reinforce political agendas that lean toward a specific brand of nationalism using the lens of public health as a context. The U.S. government under the Trump administration, and the Biden administration to a lesser extent, constructed these policies aimed primarily at refugees and asylum seekers from El Salvador, Guatemala, Honduras, and Mexico, thereby violating laws and international treaty obligations. Related Articles Correa‐Cabrera, Guadalupe. 2013. “Security, Migration, and the Economy in the Texas–Tamaulipas Border Region: The ‘Real’ Effects of Mexico's Drug War. ” Politics & Policy 41(1): 65–82. https://doi.org/10.1111/polp.12005. Duman, Yoav H. 2014. “Reducing the Fog? Immigrant Regularization and the State. ” Politics & Policy 42(2): 187–220. https://doi.org/10.1111/polp.12065. Garrett, Terence M. 2020. “The Security Apparatus, Federal Magistrate Courts, and Detention Centers as Simulacra: The Effects of Trump's Zero Tolerance Policy on Migrants and Refugees in the Rio Grande Valley. ” Politics & Policy 48(2): 372–35. https://doi.org/10.1111/polp.12348.
Effects of Long-Term Exposure to High Altitude Hypoxia on Cognitive Function and Its Mechanism: A Narrative Review

Cognitive function is affected by low pressure and hypoxia in high-altitude environments, and is regulated by altitude and exposure time. With the economic development in the Qinghai-Tibet Plateau, the increase in work and study activities, as well as the development of plateau tourism, mountaineering, and other activities, the number of plateau immigrants is increasing daily. Long-term hypoxia challenges human physical and mental health, restricts work efficiency, and thus affects plateau economic development and human wellbeing. Therefore, it is of scientific and social significance to study how long-term exposure to the hypoxic plateau environment affects the physical and mental health of lowlanders as part of the ongoing development of the current plateau region. In this paper, we reviewed the research progress and mechanism of the effects of long-term (≥1 year) high-altitude (>2500 m) hypoxia exposure on the cognitive function of lowlanders, and suggested that the scope and sample size of the research should be expanded in the future, and that follow-up studies should be carried out to explore the time threshold of cognitive impairment and its compensatory or repair mechanism.
Assessment of Domestic Investment, Export Expansion and Economic Performance in Nigeria: A Vector Autoregression Approach

The purpose of this article is to investigate the nexus between domestic investment, export expansion and economic growth in Nigeria. To achieve this purpose, annual time series data from the period between 1981 and 2018 was tested using the Johansen co-integration analysis, VECM and the Granger-Causality test. The result of the analysis revealed an insignificant relationship between domestic investment and export expansion. Based on the Granger-Causality test, the result indicated a bi-directional relationship between domestic investment and economic growth. These results provide evidence that domestic investment and economic growth are not viewed as sources of export expansion in Nigeria during the period under review. Therefore, changes in policies and regulations to accelerate the export expansion of Nigeria will ultimately yield positive results in terms of achieving high rates of stable economic growth. Policymakers in Nigeria should search for the alternative catalyst to stimulate domestic investment and economic growth geared towards promoting long-term export expansion in Nigeria effectively.
Accounting conservatism and corporate cross- listing: The mediating effect of the corporate governance

Abstract The purpose of this paper is to investigate the relationship between accounting conservatism and companies’ cross- listing decision and the mediating role of the corporate governance mechanisms: board of directors’ characteristics and ownership structure, on this relationship. Using a sample of 60 French companies for the period 2014–2019, we find new evidence of a reverse causation relationship between accounting conservatism and cross-listing decision in the United States (US). Thus, cross-listed firms in the US are more likely to exhibit more conservative financial reports. In the reverse causality sense, more conservative firms are more likely to cross-list in the US since they can support a higher level of cross-listing costs and satisfy the higher disclosure and governance requirements which allow them to benefit from a better valuation. Our findings also support the new prediction that better governance leads to higher levels of accounting conservatism, implying a mediating impact on the relationship between accounting conservatism and cross-listing decision.
Aerodynamic performance investigation of an axial flow compressor under water ingestion

This paper presents numerical simulations of the effects of water ingestion in the axial flow compressor. A self-compiled droplet-wall interaction model is used to study the impingement of the droplets and the film fragmenting process on the surfaces of the compressor blades, which also included the splashing effects. The blade profile has been divided into small regions to effectively apply the rough wall model to capture the film-related flow losses, which has shown flow characteristics with better accuracy. The formation of water film, its shedding, the size, and the movement of droplets after film peeling have been investigated using unsteady simulations at different time intervals. The increased loss of characteristics, shortening of the operating range, and change of flow velocity angle were observed with increasing water content. Moreover, the current research work shown that an increase in the amount of water has severe aerodynamic effects that caused the shock waves to move an upstream location with an increase in intensity. A higher blockage is generated in the tip section flow as the amount of the water increased. Tip losses were very dominant as water injection rate increased, resulting an additional energy loss and performance degradation.