Miracle-dz/UniFAR-FTUs huggingface dataset:
“In the Garden, I Make Up for What I Can't in the Park”: Reconnecting Retired Adults with Nature Through Cultural Ecosystem Services from Urban Gardens

While cultural ecosystem services (CES) provided by collective urban gardens have been researched for more than a decade, how knowledge of CES can inform the governance of gardens and enhance gardeners ’ wellbeing remains a challenge. Retired adults are a group whose lives can be especially improved by collective gardening. We interviewed users of community and allotment gardens in Zagreb to explore their motivations for gardening and the influence of different forms of garden management on the generation of CES. Their responses were supplemented and contextualised by interviews with urban planners, academics and gardening activists. We used Fish et al. (2016) framework to identify CES in interviews. As expected, CES drove gardeners ’ engagement. We grouped their motivations into six categories: escape, usefulness and tradition, home-grown produce, socialising, wellness, and private oasis. Interestingly, food production was only of secondary importance as a motivator of urban gardening. Findings are used to outline recommendations for urban planners and decision-makers regarding planning, design and management of collective gardens that would amplify the generation of CES for retired gardeners.
Compassionate Treatment of Brainstem Tumors with Boron Neutron Capture Therapy: A Case Series

Brainstem tumors are heterogenous and cancerous glioma tumors arising from the midbrain, pons, and the medulla that are relatively common in children, accounting for 10% to 20% of all pediatric brain tumors. However, the prognosis of aggressive brainstem gliomas remains extremely poor despite aggressive treatment with chemotherapy and radiotherapy. That means there are many life-threatening patients who have exhausted all available treatment options and are beginning to face end-of-life stage. Therefore, the unique properties of highly selective heavy particle irradiation with boron neutron capture therapy (BNCT) may be well suited to prolong the lives of patients with end-stage brainstem gliomas. Herein, we report a case series of life-threatening patients with end-stage brainstem glioma who eligible for Emergency and Compassionate Use, in whom we performed a scheduled two fractions of salvage BNCT strategy with low treatment dosage each time. No patients experienced acute or late adverse events related to BNCT. There were 3 patients who relapsed after two fractionated BNCT treatment, characterized by younger age, lower T/N ratio, and receiving lower treatment dose. Therefore, two fractionated low-dose BNCT may be a promising treatment for end-stage brainstem tumors. For younger patients with low T/N ratios, more fractionated low-dose BNCT should be considered.
Aesthetic perception of a small office with different daylighting systems

The quality of a lit environment cannot be deduced solely from the quantity of light. Therefore, daylighting studies should not only be focused on the usage of lighting metrics but should also consider the aesthetic experience. This paper examines the influence of daylighting systems on the aesthetic perception of a small office. One single side lit office was equipped with four different daylighting systems (white blinds, high-reflecting blinds, hybrid light shelf and mirror light shelf) under two sky conditions (clear sky and overcast sky). In total, eight stimuli were captured and presented via stereoscopic images. Fifty participants evaluated the images using the semantic differential scale to rate nine architectural quality attributes. The results from MANOVA indicated that both the daylighting systems and the type of sky had an effect on the aesthetic attributes, and that the significant interaction effect suggested that the aesthetic perception of a daylighting system depends on the type of sky. Subsequent statistical findings showed that the high-reflecting blinds comprised the daylighting system that scored highest in nearly all attributes under both clear and overcast sky conditions.
High Temperature High Bandwidth Fiber Optic Pressure Sensors

(Abstract) Pressure measurements are required in various industrial applications, including extremely harsh environments such as turbine engines, power plants and material-processing systems. Conventional sensors are often difficult to apply due to the high temperatures, highly corrosive agents or electromagnetic interference (EMI) noise that may be present in those environments. Fiber optic pressure sensors have been developed for years and proved themselves successfully in such harsh environments. Especially, diaphragm based fiber optic pressure sensors have been shown to possess advantages of high sensitivity, wide bandwidth, high operation temperature, immunity to EMI, lightweight and long life. Static and dynamic pressure measurements at various locations of a gas turbine engine are highly desirable to improve its operation and reliability. However, the operating environment, in which temperatures may exceed 600 °C and pressures may reach 100 psi (690 kPa) with about 1 psi (6.9kPa) variation, is a great challenge to currently available sensors. To meet these requirements, a novel type of fiber optic engine pressure sensor has been developed. This pressure sensor functions as a diaphragm based extrinsic Fabry-Pérot interferometric sensor. One of the unique features of this sensor is the all silica structure, allowing a much higher operating temperature to be achieved with an extremely low temperature dependence. In addition, the flexible nature of the sensor design such as wide sensitivity selection, and passive or adaptive temperature compensation, makes the sensor suitable for a variety of applications An automatically controlled CO 2 laser-based sensor fabrication system was developed and implemented. Several novel bonding methods were proposed and investigated to improve the sensor mechanical ruggedness and reduce its temperature dependence. An engine sensor testing system was designed and instrumented. The system generates known static and dynamic pressures in a temperature-controlled environment, which was used to calibrate the sensor. Several sensor signal demodulation schemes were used for different testing purposes including a white-light interferometry system, a tunable laser based component test system (CTS), and a self-calibrated interferometric-intensity based (SCIIB) system. All of these sensor systems are immune to light source power fluctuations, which offer high reliability and stability. The fiber optic pressure sensor was tested in a F-109 turbofan engine. The testing results prove the sensor performance and the packaging ruggedization. Preliminary laboratory and field test results have shown great potential to meet not only the needs for reliable and precise pressure measurement of turbine engines but also for any other pressure measurements especially requiring …
Explainable Artificial Intelligence for Prediction of Complete Surgical Cytoreduction in Advanced-Stage Epithelial Ovarian Cancer

Complete surgical cytoreduction (R0 resection) is the single most important prognosticator in epithelial ovarian cancer (EOC). Explainable Artificial Intelligence (XAI) could clarify the influence of static and real-time features in the R0 resection prediction. We aimed to develop an AI-based predictive model for the R0 resection outcome, apply a methodology to explain the prediction, and evaluate the interpretability by analysing feature interactions. The retrospective cohort finally assessed 571 consecutive advanced-stage EOC patients who underwent cytoreductive surgery. An eXtreme Gradient Boosting (XGBoost) algorithm was employed to develop the predictive model including mostly patient- and surgery-specific variables. The Shapley Additive explanations (SHAP) framework was used to provide global and local explainability for the predictive model. The XGBoost accurately predicted R0 resection (area under curve [AUC] = 0.866; 95% confidence interval [CI] = 0.8–0.93). We identified “turning points” that increased the probability of complete cytoreduction including Intraoperative Mapping of Ovarian Cancer Score and Peritoneal Carcinomatosis Index < 4 and <5, respectively, followed by Surgical Complexity Score > 4, patient’s age < 60 years, and largest tumour bulk < 5 cm in a surgical environment of optimized infrastructural support. We demonstrated high model accuracy for the R0 resection prediction in EOC patients and provided novel global and local feature explainability that can be used for quality control and internal audit.
The discourse analysis of Facebook and its impact on language learning: a study

This study attempts to find out the role of Facebook on language learning. Therefore it includes analyzing the discourse of different apps that are popular in use on Facebook. Different components of discourse analysis have been used to identify and explore the impairment, and how they affect one’s language practice. For the empirical data, a survey was conducted with the use of quantitative method. This paper concluded with some recommendations on what steps should be taken to overcome the limitations which were found during the research.
Clinical Utility of Multigene Profiling Assays in Early-Stage Invasive Breast Cancer: An Ontario Health (Cancer Care Ontario) Clinical Practice Guideline

Objective: The purpose of this guideline is to determine the clinical utility of multigene profiling assays in individuals with early-stage invasive breast cancer. Methods: This guideline was developed by Ontario Health (Cancer Care Ontario)’s Program in Evidence-Based Care (PEBC) through a systematic review of relevant literature, patient- and caregiver-specific consultation and internal and external reviews. Recommendation 1: In patients with early-stage estrogen receptor (ER)-positive/human epidermal growth factor 2 (HER2)-negative breast cancer, clinicians should consider using multigene profiling assays (i.e., Oncotype DX, MammaPrint, Prosigna, EndoPredict, and the Breast Cancer Index) to help guide the use of systemic therapy. Recommendation 2: In patients with early-stage node-negative ER-positive/HER2-negative disease, clinicians may use a low-risk result from Oncotype DX, MammaPrint, Prosigna, EndoPredict/EPclin, or Breast Cancer Index assays to support a decision not to use adjuvant chemotherapy. Recommendation 3: In patients with node-negative ER-positive/HER2-negative disease, clinicians may use a high-risk result from Oncotype DX to support a decision to offer chemotherapy. A high Oncotype DX recurrence score is capable of predicting adjuvant chemotherapy benefit. Recommendation 4: In postmenopausal patients with ER-positive/HER2-negative tumours and one to three nodes involved (N1a disease), clinicians may withhold chemotherapy based on a low-risk Oncotype DX or MammaPrint score if the decision is supported by other clinical, pathological, or patient-related factors. Recommendation 5: The evidence to support the use of molecular profiling to select the duration of endocrine therapy is evolving. In patients with ER-positive disease, clinicians may consider using a Breast Cancer Index (H/I) high assay result to support a decision to extend adjuvant endocrine therapy if the decision is supported by other clinical, pathological, or patient-related factors.
Ras Cheese with Different Omega Fatty Acids as Diet Plans: Cytotoxicity & Characteristics

Implantation Ras cheese with different vegetable oils as a ketogenic model in the form to use it as a diet plan to prevent obesity and investigated cytotoxicity mode of these vegetable oils on liver cancer as consequences of obesity complications in vitro system by using Huh7 cell line. The chemical and organoleptic characteristics of Ras cheese with different vegetable oils were investigated, as well as phenolic compounds and fatty acid profiles of these oils were identified and determined. Thus, findings show that the Ras cheese with different oil possesses different omega fatty acid ratios, including omega 3, 6, and 9. The total phenolic compound results indicate that sesame oil had a pronounced rank of kaempferol (2478.44 µg/g) content, followed by canola oil (628.15 µg/g). Also, peanuts oil contains the highest value of gallic acid (164.52 µg/g), while canola oil is alone contains hesperetin value (793.44 µg/g). Ras cheese with canola oil had the highest protein and fat contents compared to other Ras cheese treatments. The results showed that Ras cheese with canola and sesame oil had a pivotal role in cancer cells. It is also considered a functional dairy product that may offer vital nutrients and health benefits.
Estimation of stature from head length

Aim In this study an attempt has been made to derive a linear regression equation for estimation of stature from the length of head. Background Estimation of stature from head length is considered as an important parameter in medico-legal and forensic examinations. When highly decomposed and mutilated dead bodies with fragmentary remains are brought for postmortem examination, it becomes difficult to identify the deceased. Material Methods The present study is conducted on 506 medical students 255 male and 251 female of age group between 18 - 25 years, was conducted at Index medical college hospital and research center Indore. The measurements were taken by using standard anthropometric instruments. Results The observed data was subjected to statistical analysis like‘t’ test for correlation coefficient. The value of ‘t’ was found to be statistically significant. Simple linear regression equation derived has been used for estimation of height. Conclusion It is concluded that the head length provides good reliability in estimation of stature in forensic examinations & in medicolegal cases and the correlation between present parameters can be helpful in medico-legal cases for identification of individuals. Key Words Anthropometry, Head length, Stature
Excited-State Intramolecular Proton Transfer Dyes with Dual-State Emission Properties: Concept, Examples and Applications

Dual-state emissive (DSE) fluorophores are organic dyes displaying fluorescence emission both in dilute and concentrated solution and in the solid-state, as amorphous, single crystal, polycrystalline samples or thin films. This comes in contrast to the vast majority of organic fluorescent dyes which typically show intense fluorescence in solution but are quenched in concentrated media and in the solid-state owing to π-stacking interactions; a well-known phenomenon called aggregation-caused quenching (ACQ). On the contrary, molecular rotors with a significant number of free rotations have been engineered to show quenched emission in solution but strong fluorescence in the aggregated-state thanks to restriction of the intramolecular motions. This is the concept of aggregation-induced emission (AIE). DSE fluorophores have been far less explored despite the fact that they are at the crossroad of ACQ and AIE phenomena and allow targeting applications both in solution (bio-conjugation, sensing, imaging) and solid-state (organic electronics, data encryption, lasing, luminescent displays). Excited-State Intramolecular Proton Transfer (ESIPT) fluorescence is particularly suitable to engineer DSE dyes. Indeed, ESIPT fluorescence, which relies on a phototautomerism between normal and tautomeric species, is characterized by a strong emission in the solid-state along with a large Stokes’ shift, an enhanced photostability and a strong sensitivity to the close environment, a feature prone to be used in bio-sensing. A drawback that needs to be overcome is their weak emission intensity in solution, owing to detrimental molecular motions in the excited-state. Several strategies have been proposed in that regard. In the past few years, a growing number of examples of DSE-ESIPT dyes have indeed emerged in the literature, enriching the database of such attractive dyes. This review aims at a brief but concise overview on the exploitation of ESIPT luminescence for the optimization of DSE dyes properties. In that perspective, a synergistic approach between organic synthesis, fluorescence spectroscopy and ab initio calculations has proven to be an efficient tool for the construction and optimization of DSE-ESIPT fluorophores.
Radiation-Induced Bystander Effect Mediated by Exosomes Involves the Replication Stress in Recipient Cells

Exosomes released by irradiated cells mediate the radiation-induced bystander effect, which is manifested by DNA breaks detected in recipient cells; yet, the specific mechanism responsible for the generation of chromosome lesions remains unclear. In this study, naive FaDu head and neck cancer cells were stimulated with exosomes released by irradiated (a single 2 Gy dose) or mock-irradiated cells. Maximum accumulation of gamma H2A.X foci, a marker of DNA breaks, was detected after one hour of stimulation with exosomes from irradiated donors, the level of which was comparable to the one observed in directly irradiated cells (a weaker wave of the gamma H2A.X foci accumulation was also noted after 23 h of stimulation). Exosomes from irradiated cells, but not from control ones, activated two stress-induced protein kinases: ATM and ATR. Noteworthy is that while direct irradiation activated only ATM, both ATM and ATR were activated by two factors known to induce the replication stress: hydroxyurea and camptothecin (with subsequent phosphorylation of gamma H2A.X). One hour of stimulation with exosomes from irradiated cells suppressed DNA synthesis in recipient cells and resulted in the subsequent nuclear accumulation of RNA:DNA hybrids, which is an indicator of impaired replication. Interestingly, the abovementioned effects were observed before a substantial internalization of exosomes, which may suggest a receptor-mediated mechanism. It was observed that after one hour of stimulation with exosomes from irradiated donors, phosphorylation of several nuclear proteins, including replication factors and regulators of heterochromatin remodeling as well as components of multiple intracellular signaling pathways increased. Hence, we concluded that the bystander effect mediated by exosomes released from irradiated cells involves the replication stress in recipient cells.
Optimal placement of battery energy storage in distribution networks considering conservation voltage reduction and stochastic load composition

Deployment of battery energy storage (BES) in active distribution networks (ADNs) can provide many benefits in terms of energy management and voltage regulation. In this study, a stochastic optimal BES planning method considering conservation voltage reduction (CVR) is proposed for ADN with high-level renewable energy resources. The proposed method aims to determine the optimal BES sizing and location to minimise the total investment and operation cost considering energy saving achieved by CVR, while satisfying system operational constraints in the presence of stochastic renewable power generation. The uncertainty of load composition is also modelled through scenario analysis. The proposed planning scheme is tested in a modified IEEE 15-bus system and 43-bus radial system, respectively. The numerical results validate that the combination of CVR and BES can achieve more energy savings.
Acting out and enactment: An effort at clarity

ABSTRACT Acting out and enactment are terms in widespread use colloquially and in psychoanalytic psychotherapy to describe patient and therapist behavior. Both terms are poorly defined in the literature and have varied in interpretation as theoretical frameworks have changed. The advent of relational and inter-personal therapeutic approaches has blurred both the distinction between talking and action established by Freud and the boundaries of clinical practice. A review of the history of both terms reveals their core meaning as transgressive; by one of the analytic pair or by both, respectively. Behavior violating therapeutic boundaries and the analytic attitude, including those triggered by countertransference, are important indicators of repressed trauma as Freud originally thought. His retreat from the seduction theory led to the confusion of acting out with transference and to later authors confusing enactment with countertransference. Traumatic memories are uniquely stored and difficult to recover and characterized by hypofunction in the default mode network and hyperfunction in the central executive and salience networks leading to their behavioral expression in acting out and enactment in contrast to verbal expression. Thus understood these forms of behavior can make an important contribution to the “talking cure. ”
New Zealand Blackcurrant extract supplementation does not improve repeated sprint ability

Blackcurrants are an excellent source of antioxidant and anti-inflammatory agents, and recent studies have found them to facilitate performance and recovery in aerobic activities. However, limited research exists in intermittent or anaerobic settings despite known oxidative and inflammatory stresses. Therefore, we examined the effects of New Zealand Blackcurrant (NZBC) on repeated sprint ability (RSA) and recovery parameters. Sixteen recreationally active females were supplemented with either NZBC (1.6mg.kg-1 anthocyanin content; ViBERi, Timaru, New Zealand) or a matched placebo (artificial sweetener) for 7 days in a randomized, double-blind, parallel-group design. On day 7 participants performed the RSA test which consisted of ten 30m shuttle sprints interspersed with a 30 second recovery period. Blood lactate was assessed 1-, 3-, 5-, and 10-minutes post-test. The same protocol was then replicated the following day. NZBC improved mean sprint time from baseline by 2.0% and fastest sprint time by 2.7%. Placebo also improved sprint time by 2.3%. Compared to the placebo group the NZBC group typically performed better in all RSA test outcomes, however the differences were deemed unclear and non-significant. Lactate responses post RSA on average tended to be higher on both days for the NZBC group compared to placebo group (15.1 – 32.5%). A moderate difference (ES: -0.64) was observed between groups post 7-days of supplementation for lactate clearance from 5-minutes to 10-minutes post-test with NZBC leading to a decrease of 23.7%. In conclusion, NZBC supplementation for 7-days does not improve repeated sprint ability when compared to placebo.
TELKOMNIKA Telecommunication Computing Electronics and Control

Karrar Shakir Muttair, Oras Ahmed Shareef, Ahmed Mohammed Ahmed Sabaawi, Mahmood Farhan Mosleh Department of Computer Techniques Engineering, College of Technical Engineering, The Islamic University, Najaf, Iraq Department of Computer Engineering Techniques, Electrical Engineering Technical College, Middle Technical University, Baghdad, Iraq Department of Electronics Engineering, College of Electronics Engineering, Ninevah University, Mosul, Iraq