Miracle-dz/UniFAR-FTUs huggingface dataset:
The changes of level of knowledge, perception and behaviour of secondary school students on HIV/AIDS in Penang: Pre and post intervention

The objectives of this study is to analyze the level of knowledge, perceptions and behaviour of school adolescents on HIV/AIDS before and after the application of the HIV AIDS intervention module. This study involved 600 students aged 15, 16 and 17 years old in Penang, through three sessions involving pre-test, intervention and post-test. The results showed that there was a positive changes in the level of knowledge, perceptions and behaviours of the respondents after the intervention process was carried out using the modules. The hypothesis test for knowledge has shown that there is a change in the level of knowledge of the respondents after receiving information on HIV/AIDS (t = -46.561, sig. <0.05 and post knowledge’s mean was 13.813 is higher than pre knowledge’s mean, 8.715). In terms of behaviour, there was also a change in the negative behaviour of the respondents after information sharing interventions on HIV/AIDS (t = -8.716 and sig. <0.05 and post behavioural’s mean was 4.067, higher than the pre behavioural mean).
DYNAMICS OF DEPOSITION AND FOSSIL PRESERVATION AT THE EARLY EOCENE OKANAGAN HIGHLANDS OF BRITISH COLUMBIA, CANADA: INSIGHTS FROM ORGANIC GEOCHEMISTRY

Abstract: The early Eocene Okanagan Highland fossil sites of Washington (USA) and British Columbia (Canada) contain exquisitely preserved plant and insect fossils that showcase a critical time and place in the evolution of the Northern Hemisphere temperate deciduous biome. A comprehensive understanding of the dynamics of fossil deposition and preservation at these sites is not fully resolved but is critical for reliable reconstructions of these ancient forests. To expand on previous interpretations (e.g., deep, stratified, anoxic lake bottoms) and address uncertainties about the environment of deposition (e.g., distance to shore, influence of diatoms), we analyzed sediment samples from three Okanagan Highland fossil sites—McAbee, Falkland, and Driftwood Canyon—for organic biomarkers, their stable carbon isotopic compositions, and glycerol dialkyl glycerol tetraethers (GDGTs; at McAbee only). Terpenoids suggest relative trends in gymnosperm abundance between sites that agree with prior macrofossil evidence, though absolute values may overestimate local gymnosperm abundance. A combination of biomarker evidence indicates a predominantly autochthonous aquatic source (e.g., diatoms) for organic matter in shale and mudstone samples, even contributing to long chain n-alkanes and likely to branched GDGTs, which are often assumed to be terrestrially sourced. In combination with biomarker evidence for anoxia and stratification, fossiliferous shales are interpreted to have been deposited offshore in deep and mesotrophic lakes that were thermally stratified with an anoxic hypolimnion, away from in-flowing tributaries, while a coal horizon at Driftwood Canyon was deposited in a shallower, eutrophic, anoxic wetland. Anoxic conditions likely minimized some degradation-based biases and promoted high quality fossil preservation. Deposition of sediment and fossil remains offshore and away from inflowing tributaries suggest fossil plants were locally sourced but highlights the need for careful consideration of transport-induced biases.
Polyphenol Characterization and Antioxidant Activity of Grape Seeds and Skins from Sicily: A Preliminary Study

The interest in the consumption of health-promoting foods has led to identifying derivatives of the wine industry as products to increase the functional properties of different foods or to design new functional foods. The main goal of this study is to characterize and valorize byproducts and wastes of Sicilian grapes as new sources of bioactive components, from the perspective of a circular economy and a biorefinery approach. In particular, this research investigated: 1. the total phenolic content and antioxidant activities and 2. the phenolic profiles of free and bound fractions of defatted grape seeds and red grape skins from Sicily. Defatted grape seeds (DGS) and red grape skins (RGSK) are rich in phenolic compounds. Twenty biophenols were found in the defatted seeds and red grape skins. Particularly interesting were the results obtained after basic hydrolysis, which allowed the release of biophenols from the matrix. The degreased grape seeds showed p-coumaric acid levels at 4641.65 µg g−1, gallic acid at 2649.23 µg g−1, and caffeic acid at 1474.13 µg g−1, along with appreciable quantities of myricetin, epicatechin, and quercetin. As a sustainable approach, the reuse and the value added of the byproducts and wastes of grapes grown in Sicily is shown, which makes possible new applications in different fields, i.e., nutraceuticals.
At Home or In Person? A Comparison of Informal Learning Environments for Secondary Students

Due to the sudden onset of the COVID-19 pandemic, the comparison of online versus traditional face-to-face (FTF) environments has now come under review. The research of online informal learning spaces for K–12 education in particular is underdeveloped and requires more investigation. The purpose for this paper is to report an analysis of the differences in students’ career interest after an online and a FTF STEM camp. One group (n = 45) of participants attended a one-week STEM camp online while another group (n = 62) attended a one-week STEM camp in person. In this mixed methods study, pre and posttest scores of a STEM career interest survey were analyzed and semistructured interviews were conducted. For the quantitative portion, p-values from paired-sample t-tests are reported as well as Cohen’s d effect sizes. Interviews were coded using the constant comparative method and were analyzed using thematic analysis. The quantitative results indicate that both the online and FTF camps may improve different aspects of a student’s career interest. The qualitative results consist of four main themes: social connections, learning and teaching, preference, and opportunities. Aspects of an informal learning environment may work in person but may not translate to an online environment. Therefore, improvements should be made based on the specific learning environment, not on the general product of a course.
Associated factors of neonatal near miss among newborns of adolescent mothers in Brazil

ABSTRACT Objective: To identify the associated factors of neonatal near miss among newborns of Brazilian adolescents and to compare their occurrence in young women aged 12 to 16 years and 17 to 19 years. Method: Cross-sectional, hospital-based study, using data from the study Nascer no Brasil (“Birth in Brazil”) on puerperal adolescents and their newborns in all regions of Brazil. Multiple and univariate logistic regression were employed to identify the associated factors of neonatal near miss. Results: The following factors were found to be associated to neonatal near miss among newborns of adolescent mothers: public source of payment (OR = 4.57, 95% CI = 2.02–10.32), having to seek help in different maternity hospitals (OR = 1.52; 95% CI = 1.05–2.20), and maternal near miss (OR = 5.92; 95% CI = 1.94–18.05), in addition to a record of low weight in a previous pregnancy (OR = 3.12; 95% CI = 1.61–6.04) and twin pregnancy (OR = 7.49; 95% CI = 3.28–16.82). Conclusion: Neonatal near miss affected newborns of adolescent mothers in both age groups equally. Also, the determinant factors of neonatal near miss can be mostly reduced with qualified prenatal, labor, and birth care.
Correlation of Carotenoids Content and ASTA Values of Pepper (Capsicum chinense) Genetic Resources

In this study, 226 Capsicum chinense genetic resources were analyzed using high-performance liquid chromatography and a spectrophotometer to measure and compare their carotenoid content and American Spice Trade Association (ASTA) color values, respectively. The total carotenoid content and ASTA values of the 226 pepper genetic resources were found to be in the range of 7.04–2430.85 mg/100 g dry weight (DW) and 0–221.32, respectively. Capsanthin, capsorubin, lutein, zeaxanthin, antheraxanthin, violaxanthin, α-carotene, β-carotene, and β-cryptoxanthin were the individual carotenoids studied. The average content of each carotenoid (n = 226) in mg/100 g DW was as follows: capsanthin (325.77), antheraxanthin (136.34), capsorubin (82.36), β-carotene (59.11), violaxanthin (46.54), zeaxanthin (43.21), α-carotene (13.91), β-cryptoxanthin (9.67), and lutein (2.72). A strong positive correlation was observed between total carotenoid content and ASTA value (r = 0.965). Likewise, the individual carotenoid content and ASTA value revealed a strong correlation, such as antheraxanthin (r = 0.964), capsanthin (r = 0.946), and capsorubin (r = 0.858). Three genetic resources with a total carotenoid content above 2000 mg/100 g DW were obtained, such as IT261426 (2430.85 mg/100 g DW), IT183657 (2077.55 mg/100 g DW), and IT261213 (2062.54 mg/100 g DW). The findings of this study will assist in the selection of genetic resources with high carotenoid content and ASTA value that can be used to develop and breed new pepper varieties. Also, detailed results of ASTA value correlation with carotenoids in C. chinense genetic resources are provided.
Fracture, Friction, and Permeability of Ice

Water ice Ih exhibits brittle behavior when rapidly loaded. Under tension, it fails via crack nucleation and propagation. Compressive failure is more complicated. Under low confinement, cracks slide and interact to form a frictional (Coulombic) fault. Under high confinement, frictional sliding is suppressed and adiabatic heating through crystallographic slip leads to the formation of a plastic fault. The coefficient of static friction increases with time under load, owing to creep of asperities in contact. The coefficient of kinetic (dynamic) friction, set by the ratio of asperity shear strength to hardness, increases with velocity at lower speeds and decreases at higher speeds as contacts melt through frictional heating. Microcracks, upon reaching a critical number density (which near the ductile-to-brittle transition is nearly constant above a certain strain rate), form a pathway for percolation. Additional work is needed on the effects of porosity and crack healing. ▪ An understanding of brittle failure is essential to better predict the integrity of the Arctic and Antarctic sea ice covers and the tectonic evolution of the icy crusts of Enceladus, Europa, and other extraterrestrial satellites. ▪ Fundamental to the brittle failure of ice is the initiation and propagation of microcracks, frictional sliding across crack faces, and localization of strain through both crack interaction and adiabatic heating.
Effect of Microwave Irradiation on Acid Hydrolysis of Faba Bean Starch: Physicochemical Changes of the Starch Granules

Starch is the most abundant carbohydrate in legumes (22–45 g/100 g), with distinctive properties such as high amylose and resistant starch content, longer branch chains of amylopectin, and a C-type pattern arrangement in the granules. The present study concentrated on the investigation of hydrolyzed faba bean starch using acid, assisted by microwave energy, to obtain a possible food-grade coating material. For evaluation, the physicochemical, morphological, pasting, and structural properties were analyzed. Hydrolyzed starches developed by microwave energy in an acid medium had low viscosity, high solubility indexes, diverse amylose contents, resistant starch, and desirable thermal and structural properties to be used as a coating material. The severe conditions (moisture, 40%; pure hydrochloric acid, 4 mL/100 mL; time, 60 s; and power level, 6) of microwave-treated starches resulted in low viscosity values, high amylose content and high solubility, as well as high absorption indexes, and reducing sugars. These hydrolyzed starches have the potential to produce matrices with thermo-protectants to formulate prebiotic/probiotic (symbiotic) combinations and amylose-based inclusion complexes for functional compound delivery. This emergent technology, a dry hydrolysis route, uses much less energy consumption in a shorter reaction time and without effluents to the environment compared to conventional hydrolysis.
The Rice Serine/Arginine Splicing Factor RS33 Regulates Pre-mRNA Splicing during Abiotic Stress Responses

Abiotic stresses profoundly affect plant growth and development and limit crop productivity. Pre-mRNA splicing is a major form of gene regulation that helps plants cope with various stresses. Serine/arginine (SR)-rich splicing factors play a key role in pre-mRNA splicing to regulate different biological processes under stress conditions. Alternative splicing (AS) of SR transcripts and other transcripts of stress-responsive genes generates multiple splice isoforms that contribute to protein diversity, modulate gene expression, and affect plant stress tolerance. Here, we investigated the function of the plant-specific SR protein RS33 in regulating pre-mRNA splicing and abiotic stress responses in rice. The loss-of-function mutant rs33 showed increased sensitivity to salt and low-temperature stresses. Genome-wide analyses of gene expression and splicing in wild-type and rs33 seedlings subjected to these stresses identified multiple splice isoforms of stress-responsive genes whose AS are regulated by RS33. The number of RS33-regulated genes was much higher under low-temperature stress than under salt stress. Our results suggest that the plant-specific splicing factor RS33 plays a crucial role during plant responses to abiotic stresses.
Digital transition in Chinese newspaper industry: the case studies of two metropolitan newspaper companies

This study focuses on digital transition in the Chinese newspaper industry and on associated changes in management and business practice at newspaper publishers. Drawing on a case study analysis of two leading metropolitan newspaper companies – the Qianjiang News Chain and the Nandu News Chain, it sets out to investigate how newspaper publishers are adjusting their management strategies and production practices to adapt to technological changes and ensure their survival. It also examines to what extent the changes are in line with the relevant government policies. Looking specifically at electronic retailing and online marketing operated by the two publishers respectively, this dissertation will address three questions. How the strategic management of newspaper companies in China is changing to facilitate the operation of new businesses in the Internet era. How content production related to the new businesses is changing in response to digital transition and the integration of editorial and commercial activities. To what extent the altered practices of newspaper companies are either consistent or conflicting with the requirement of related government policies. Findings of the empirical analysis are in three aspects. Firstly, in order to facilitate the operation of new businesses, the strategic management of QNC and NNC are changing in three aspects: corporate expansion, organisational re-structuring and cultural adaption. Secondly, the production activities of QNC and NNC are simultaneously affected by the practices of digitisation and commercialisation, which is reflected by the special content products – promotional articles. Lastly, with the changes of organisational activities, the industry practices of QNC and NNC are consistent to the inclination of certain state policies on the one hand, and conflict with some established government regulations on the other. In summary, the practice of new business in QNC and NNC is the miniature of the transition in the Chinese newspaper industry, which inherits the features formed in the decade of evolvement. Meanwhile, as the two publishers are pioneers in the Chinese newspaper industry, their practices lead the trend of novel exploration in the future.
Control of a multi-terminal HVDC (MTDC) system and study of the interactions between the MTDC and the AC grids.

HVDC transmission systems are largely used worldwide, mostly in the form of back-to-back and point-to-point HVDC, using either thyristor-based LCC or IGBT-based VSC. With the recent deployment of the INELFE HVDC link between France and Spain, and the commissioning in China of a three-terminal HVDC transmission system using Modular Multilevel Converters (MMCs), a modular design of voltage source converters, the focus of the scientific community has shifted onto the analysis and control of MMC-based HVDC transmission systems. In this thesis, the average value models of both a standard 2-level VSC and an MMC are proposed and the most interesting difference between the two converter technologies -the control of the stored energy in the MMC- is emphasised and explained. These models are then linearised, expressed in state-space form and validated by comparing their behaviour to more detailed models under EMT programs. Afterwards, these state-space representations are used in the modelling of HVDC transmission systems, either point-to-point or Multi-Terminal HVDC (MTDC). A modal analysis is performed on an HVDC link, for both 2-level VSCs and MMCs. The modes of these two systems are specifed and compared and the independent control of the DC voltage and the DC current in the case of an MMC is illustrated. This analysis is extended to the scope of a 5-terminal HVDC system in order to perform a stability analysis, understand the origin of the system dynamics and identify the dominant DC voltage mode that dictates the DC voltage response time. Using the Singular Value Decomposition method on the MTDC system, the proper design of the voltage-droop gains of the controllers is then achieved so that the system operation is ensured within physical constraints, such as the maximum DC voltage deviation and the maximum admissible current in the power electronics. Finally, a supplementary droop "the frequency-droop control" is proposed so that MTDC systems also participate to the onshore grids frequency regulation. However, this controller interacts with the voltage-droop controller. This interaction is mathematically quantified and a corrected frequency-droop gain is proposed. This control is then illustrated with an application to the physical converters of the Twenties project mock-up.
A goal by any other name: Effects of different goal elicitation methods on goal pursuit

There are many ways in which researchers ask participants about their personal goals or projects, yet findings are subsequently considered interchangeable. This study experimentally tested whether different ways of asking participants about their goals elicits different goals and impacts reports of goal progress. Undergraduate participants (N = 285) were assigned to one of three conditions (personal projects, personal goals, open-ended goals), listed an unlimited number of goals they were currently pursing, rated each goal on a series of goal characteristics, and six weeks later reported on their goal progress. Results indicated that participants reported significantly more goals in the personal project condition than in the other two conditions, and that these goals were rated as less difficult. Overall, the present study provides further insight into the effects of the elicitation methods employed in goal pursuit research.
259-OR: Stem Cell–Derived, Fully Differentiated Islet Cells for Type 1 Diabetes

Cadaveric islet transplantation can achieve glycemic control in T1D, but cadaveric islet quantity and quality are limiting. We report the first patient-administered VX-880, an investigational allogeneic stem cell–derived, fully differentiated, pancreatic islet cell replacement therapy. A 64-year-old male with a 40-year history of T1D complicated by impaired awareness of hypoglycemia with 5 severe hypoglycemic events (SHEs) the year before VX-880 was receiving 34U insulin/day at baseline (HbA1c 8.6%; undetectable fasting and stimulated C-peptide) . After a single VX-880 infusion at half target dose, fasting C-peptide was detected by Day 29 and increased rapidly; HbA1c and daily insulin decreased in parallel. At Day 90, robust increases in fasting and stimulated C-peptide, improved glycemic control, and a substantial reduction in exogenous insulin administration were observed and continued to improve through last time point assessed (Table) . VX-880 was generally safe and well tolerated; most AEs were mild or moderate and consistent with immunosuppression. The most common AEs were SHEs (not serious or related to VX-880) , which occurred in the perioperative period. There was 1 serious AE of rash (mild, unrelated to VX-880) , which resolved. These unprecedented results are the first evidence that stem cell–derived islets can restore insulin production and glucose control in T1D. The study continues to enroll and dose patients. J.F. Markmann: Consultant; Vertex Pharmaceuticals Incorporated. L.S. Kean: Advisory Panel; HiFiBio, Mammoth Biosciences, Other Relationship; Bristol-Myers Squibb Company, Research Support; Bluebird Bio, Gilead Sciences, Inc., Magenta Therapeutics, Merck & Co., Inc., Novartis AG, Regeneron Therapeutics. A.L. Peters: Advisory Panel; Abbott Diabetes, AstraZeneca, Eli Lilly and Company, Novo Nordisk, Shouti, Vertex Pharmaceuticals Incorporated, Zealand Pharma A/S, Other Relationship; Omada Health, Inc., Research Support; Abbott Diabetes, Dexcom, Inc., Insulet Corporation, Leona M. and Harry B. Helmsley Charitable Trust, Stock/Shareholder; Teladoc Health. P.Witkowski: Advisory Panel; Sernova, Corp., Vertex Pharmaceuticals Incorporated. C.Ricordi: Advisory Panel; Vertex Pharmaceuticals Incorporated. A.Naji: None. M.R. Rickels: Advisory Panel; Sernova, Corp., Vertex Pharmaceuticals Incorporated, Zealand Pharma A/S, Consultant; L-Nutra Inc. M.Alba: None. G.Marigowda: None. L.Ross: Employee; Vertex Pharmaceuticals Incorporated. C.Wang: Employee; Vertex Pharmaceuticals Incorporated. F.Pagliuca: Employee; Vertex Pharmaceuticals Incorporated, Other Relationship; Vertex Pharmaceuticals Incorporated, Stock/Shareholder; Vertex Pharmaceuticals Incorporated. B.Sanna: Employee; Vertex Pharmaceuticals Incorporated.
Assessment of disaster planning in humanitarian supply chain management (HSCM), Khuzestan: 2012

Background and Objective: Disasters are scarce events; nevertheless, to prepare organizations for events and return to normal condition the accurate planning and education is essential. This study aimed to assess disaster planning in humanitarian supply chain management (HSCM) in Khuzestan Province in 2012. Materials and Methods: In this descriptive-cross sectional study, statistical population involved the top managers of the crisis management unit, emergency medicine services (EMS) and relief and rescuing center of the West Country in the Khuzestan Province. Because of the limited number of the statistical population, a census method was used. The data were collected using a checklist developed by reviewing literature and through observation and interview. Data were analyzed by descriptive statistics like frequency, percentage and mean percentage and using by SPSS v.18. Results: The results indicated that generally the status of planning of humanitarian supply chain management (HSCM) in the response phase was good. Emergency Medicine Services (EMS) and center of relief and rescuing were ranked respectively in the moderate and good situations. The dimensions of human resource and the control were respectively in the best and the worst condition. Conclusions: According to findings, disaster planning in humanitarian supply chain management (HSCM) in the response phase requires more attention in aspect of control. Generally, at the occurrence of disasters stage, particularly in supervision and control, paying attention to HSCM is necessary. So, we stress on the necessary reform of the program to ensure the proper supply of resources and cover the needs.