Miracle-dz/UniFAR-FTUs huggingface dataset:
Expanding Donor Options for Lung Transplant: Extended Criteria, Donation After Circulatory Death, ABO Incompatibility, and Evolution of Ex Vivo Lung Perfusion

Only using brain-dead donors with standard criteria, the existing donor shortage has never improved in lung transplantation. Currently, clinical efforts have sought the means to use cohorts of untapped donors, such as extended criteria donors, donation after circulatory death, and donors that are ABO blood group incompatible, and establish the evidence for their potential contribution to the lung transplant needs. Also, technical maturation for using those lungs may eliminate immediate concerns about the early posttransplant course, such as primary graft dysfunction or hyperacute rejection. In addition, recent clinical and preclinical advances in ex vivo lung perfusion techniques have allowed the safer use of lungs from high-risk donors and graft modification to match grafts to recipients and may improve posttransplant outcomes. This review summarizes recent trends and accomplishments and future applications for expanding the donor pool in lung transplantation.
Bayesian Multidimensional Scaling and Choice of Dimension

Multidimensional scaling is widely used to handle data that consist of similarity or dissimilarity measures between pairs of objects. We deal with two major problems in metric multidimensional scaling–configuration of objects and determination of the dimension of object configuration–within a Bayesian framework. A Markov chain Monte Carlo algorithm is proposed for object configuration, along with a simple Bayesian criterion, called MDSIC, for choosing their dimension. Simulation results are presented, as are real data. Our method provides better results than does classical multidimensional scaling and ALSCAL for object configuration, and MDSIC seems to work well for dimension choice in the examples considered.
ESTIMATING THE FALSE NEGATIVE FRACTION FOR A MULTIPLE SCREENING TEST FOR BOWEL CANCER WHEN NEGATIVES ARE NOT VERIFIED

This paper aims to estimate the false negative fraction of a multiple screening test for bowel cancer, where those who give negative results for six consecutive tests do not have their true disease status verified. A subset of these same individuals is given a further screening test, for the sole purpose of evaluating the accuracy of the primary test. This paper proposes a beta heterogeneity model for the probability of a diseased individual ‘testing positive’ on any single test, and it examines the consequences of this model for inference on the false negative fraction. The method can be generalized to the case where selection for further testing is informative, though this did not appear to be the case for the bowel‐cancer data.
Continuity Properties of Minimizers of Integral Functionals in a Limit Case

Abstract We prove continuity of minimizers of integral functionals of the form ∫ Ω [ f 0 ( x , u , Du )+ hDu ], where the integrand f 0 ( x , η, ξ) grows like |ξ| p , with p >1, and h is in a suitable Lorentz space. Continuity of solutions of nonlinear equations of the form div A ( x , u , Du )=div h is also proved, where A ( x , η, ξ) grows like |ξ| p −1 .
Inventory Systems with Unreliable Suppliers

The aim of this article is to establish the optimal control of a periodic-review inventory system with two suppliers. One of them delivers orders immediately, the other one is unreliable delivering the orders immediately only with probability p ∈ (0, 1). Two cases are considered. In the first case, it is possible to order any inventory amount from each of suppliers. In the second case, the system budget is restricted.
Development and performance evaluation of a motorized tumble barrel feed/food mixer

A tumble barrel food /feed mixer was designed and fabricated. It has a volumetric capacity of 0.33 m3 . The tumble barrel mixer consists of a hopper, a stainless steel barrel with baffles. It is mounted on a steel framework and driven by a shaft connected to stirrers inside the baffles. The baffles are alternatively placed in the barrel in such a way that they do not touch the stirrers during operation. The shaft is driven by a 3HP (2,25 kW) variable speed electric motor. Performance tests were conducted on the machine after fabrication using the ASAE (R2006) test standards, and also Completely Randomized Design (CRD). Three speeds of the mixer, 100,150 and 200 rpm (min-1 ) ( and four mixing times of 5,10,15 and 20 minutes were studied as they affected the Degree of Mixing (DM) of ground and shelled corn samples in the mixer. Results obtained showed, there was an increase in the degree of mixing as the speed of the machine increased from 100 to 200 rpm (min-1 ). Also the degree of mixing increased as the time of mixing increased from 5mins to 20 minutes for the three speeds studied. From the Analysis of variance tables, the calculated F-values were very much higher than the tabulated values at 5% probability. These indicate a high significance of the effect of speeds of mixing on the degree of mixing of the tumble barrel mixer. The speed of 150 rpm (min-1 ) gave the highest effect in the tumble mixer. From the difference of means tables, there were significant differences in the degree of mixing for 100 and 150 rpm (min-1 ) speeds for all the different time of mixing durations. However, in the 200 rpm (min-1 ) speed, there was no significant difference in the DM between the 15 to 20 minutes mixing time duration.
Ecological Features and Conservation of Urtica rupestris Guss. (Urticaceae): A Narrow Endemic Species of Sicily

The conservation actions of endangered plant species require a clear knowledge of their habitats. Urtica rupestris Guss. (Urticaceae) is a rare endemic plant species occurring on shady cliffs in the southern-eastern part of Sicily. In the last century, the extreme anthropogenic alterations of Hyblaean plateau have caused the continuous and unrestrained fragmentation of natural habitats and consequently the reduction and disappearance of some plant species. A total of 52 vegetation plots, of which 34 are unpublished, were analyzed in order to characterize the floristic composition of the U. rupestris community. All the relevés were classified using classification and ordination methods. The species is mainly linked to shady and wet rock habitats, and only secondarily colonizes the undergrowth shrubs. According to IUCN criteria, we propose a new risk status for this species and the establishment of a new habitat (92/43CEE) for correct long-term conservation. Finally, a new association, Urtico rupestris-Adiantetum capilli-veneris, which falls within the Polysticho setiferi-Phyllitidion scolopendrii alliance (Adiantetea capilli-veneris class), was described. This study can provide useful information for the management and conservation of U. rupestris.
The Evolving Landscape of Leptomeningeal Cancer from Solid Tumors: A Systematic Review of Clinical Trials

Simple Summary Leptomeningeal carcinomatosis is a devastating complication of solid malignancies and can occur concurrently in patients with brain metastasis. Despite progress in the treatment of brain metastasis, the survival of patients with leptomeningeal cancer remains stagnant. In the present work, we aimed to conduct a systematic review to evaluate outcome measures, complications, adverse effects, and limitations of therapies explored, with the objective to critically evaluate previous treatments as well as discuss the landscape of ongoing clinical trials for leptomeningeal carciomatosis. Abstract Leptomeningeal carcinomatosis (LMC) is a fatal but uncommon complication occurring in 5–15% of patients with stage IV cancer. Current treatment options are ineffective at managing leptomeningeal spread, with a median overall survival (mOS) of 2–6 months. We aimed to conduct a systematic review of the literature to identify past and future therapies for LMC from solid tumors. Forty-three clinical trials (CTs) published between 1982–2022 were identified. Of these, 35 (81.4%) were non-randomized CTs and 8 (18.6%) were randomized CTs. The majority consisted of phase I (16.3%) and phase II CTs (65.1%). Trials enrolled patients with LMC from various primary histology (n = 23, 57.5%), with one CT evaluating LCM from melanoma (2.4%). A total of 21 trials evaluated a single modality treatment. Among CTs, 23.7% closed due to low accrual. Intraventricular (ITV)/intrathecal (IT) drug delivery was the most common route of administration (n = 22, 51.2%) vs. systemic drug delivery (n = 13, 30.3%). Two clinical trials evaluated the use of craniospinal irradiation for LMC with favorable results. LMC continues to carry a dismal prognosis, and over the years, increments in survival have remained stagnant. A paradigm shift towards targeted systemic therapy with continued standardization of efficacy endpoints will help to shed light on promising treatments.
The Scientific Impact of Abstracts on Functional Urology – an Evaluation of the European Association of Urology (EAU) and International Continence Society (ICS) congresses of 2015 until 2019

At the annual congresses of the European Association of Urology (EAU) and the International Continence Society (ICS) many clinicians and scientists present their recent research work. Before an abstract is published in a journal, it is preferred to present it at scientific meetings [1]. The quality and value of these annual scientific meetings can be measured by the publication rates of abstract presentations [2]. The aim of the present study was to find out what proportion of all abstracts on functional urology published at the EAU and ICS were published as full papers. In addition, we analyzed the differences between functional urology related abstracts presented EAU and ICS. Moreover, by using a self-designed discrepancy score we intended to find out whether the actual concluding messages of presented abstracts would differ from the final publication.
Composition of Behavioural Assume–Guarantee Contracts

The growing complexity of modern engineering systems necessitates a method for design and analysis that is inherently modular. Methods based on using contracts for system design have successfully tackled this issue for a variety of system classes, but mostly in the context of discrete software systems. Motivated by this, we present assume–guarantee contracts for continuous linear dynamical systems with inputs and outputs. Such contracts serve as system specifications through two aspects. The assumptions specify the dynamic behavior of the environment of the system, which provides inputs for it, whereas, the guarantees specify the desired dynamic behavior of the output of the system when interconnected with a relevant environment. This is formalized by utilizing the behavioral approach to system theory. We define and characterize notions of contract implementation and contract refinement, where the latter is used to compare contracts. We also define and characterize two notions of contract composition that allow one to reason about two types of system interconnections: series and feedback. The properties of refinement and composition allow contracts to be used for modular design and analysis.
Sublinear functions of measures and variational integrals

The original purpose of this paper was to establish that certain non-parametric variational integrals may be considered as measures on the domain of definition of the admissible functions. This was accomplished by exhibiting an explicit formula for the functional involved, the formula containing within itself, in the case of the surface area integral, a proof both of Tonelli’s celebrated theorem on Lebesgue area and of a less well known but deeper result of Verchenko. It soon became apparent, however, that the basic techniques were considerably more general, and could, in fact, be phrased entirely apart from variational calculus simply as a method of generating measures in terms of other measures. We shall follow this more abstract course in the paper, and only turn directly to variational calculus in the final section. Consider a countably additive set function on a g-ring R of subsets of a basic set S. The function g will be supposed to have its values in a real Banach space , which for particular applications may be the real numbers R1, or the Euclidean number space R. Let (p) be a bounded sublinear functional on into the reals. By this we mean that for all p, q in
Rheological properties of nondilute suspensions of deformable particles

The creeping flow equations have been solved to account for effects of shear on drop shape when the influence of neighboring drops is considered. A cell model is used to account for finite concentrations of the dispersed phase. From these results a constitutive equation is derived and implications for several flows are discussed. The shape and orientation of drops are computed and compared with existing data. Finally, dynamic viscosity and rigidity are obtained for nondilute suspensions of viscoelastic particles in an oscillatory shear flow.
Implementation of Physical Education component within the basic science and technology curriculum and the time allocation in comparison to other basic science and technology subjects

The objective is to assess the implementation of physical education (PE) component within the basic science technology subjects (BST) curriculum and the time allocation in comparison to other BST subjects. Descriptive survey research was adapted. The population was 109,778, comprising 109,383 students, 78 PE teachers and 317 head teachers of public Junior Secondary School (JSS), representing eighteen (18) Local Government Areas (LGAs) in Edo State. The sample size was 1,060 comprising 70 PE teachers, 90 Head teachers and 900 students; and they were selected using multi-stage sampling procedure. Two instruments were used to obtain data: “Implementation of PE component of BST curriculum questionnaire (IPECBSTCQ) and Time Allocation and General time table information for PE and BST subjects schedule (TAGTIPEBSTS). The cronbach alpha statistics was used to determine the reliability of the instrument, the r-value of 0.95 was obtained for the IPECBSTCQ. Main findings suggest an endorsement of policy statements related to PE within the BST by the PE and Head teachers. Also, PE is not accorded necessary attention compared to other subjects within the BST curriculum. It was concluded that PE and other Head teachers were conversant with National Policy on Education (NPE) stipulations as relates to PE within the BST curriculum; just as it was necessary for more time to be allotted to PE on the general time table in comparison to other BST subjects. It was chiefly recommended that supervisory officials of the Ministry of Education should ensure strict adherence to policy implementation related to PE within the BST.
Adolescent Girls’ Experiences Regarding Teenage Pregnancy in the Rural Villages of Limpopo Province, South Africa

Every year, 7.3 million girls become pregnant before they turn 18. Teenage pregnancy increases when girls are denied the right to make decisions about their sexual health and well-being, which is a gender equality issue. Among the challenges of gender equality are those expectations that communities have about girls and early motherhood, sexual violence, and rape. Another challenge is the early marriages of children to older men coupled with the unique risks faced by these girls during pregnancy, for example, the interruption of their education, health risks, such as HIV, premature birth, and increased maternal mortality, denying the girls the right to live a healthy life. This study sought to explore the experiences of adolescent girls regarding teenage pregnancy in the rural villages of the Mopani District, Limpopo. A descriptive, explorative, and qualitative design was followed to collect data from 20 pregnant teenagers in a 13–19 years-old age group. A nonprobability purposive sampling method was used to select the participants from the three villages of the Mopani District. The data were collected using an in-depth individual interview. Tesch’s eight steps of data analysis were also applied. The study findings reveal several factors that explain the high rates of teenage pregnancy in rural Limpopo. Among these are the socioeconomic and cultural factors that predispose teens to pregnancy. The consequences of teenage pregnancy were expressed in terms of regret and ill health.
Self‐imaging in homogeneous planar optical waveguides

The formation of one‐dimensional self‐images in planar optical waveguides is described ray optically and is demonstrated experimentally. The self‐images can be erect or inverted, single or multiple, and magnified or demagnified. Possible applications in integrated optics include a cross over of strip guides, a simple 3‐dB directional coupler, and a filter.
Integrated Modeling of European Migration

International migration data in Europe are collected by individual countries with separate collection systems and designs. As a result, reported data are inconsistent in availability, definition, and quality. In this article, we propose a Bayesian model to overcome the limitations of the various data sources. The focus is on estimating recent international migration flows among 31 countries in the European Union and European Free Trade Association from 2002 to 2008, using data collated by Eurostat. We also incorporate covariate information and information provided by experts on the effects of undercount, measurement, and accuracy of data collection systems. The methodology is integrated and produces a synthetic database with measures of uncertainty for international migration flows and other model parameters. Supplementary materials for this article are available online.
Power Calculations for Likelihood Ratio Tests in Generalized Linear Models

SUMMARY Recently Self and Mauritsen (1988, Biometrics 44, 79-86) described an approach for sample size/power calculations within the framework of generalized linear models that is based on a noncentral chi-square approximation to the distribution of score statistics. In this work, we present another approach to this same problem that is based on a noncentral chi-square approximation to the distribution of the likelihood ratio statistic. This approach is easier to implement than the previous one and simulation studies indicate that it is accurate over a much wider range of parameter values and data configurations than the earlier method. The new method is also applied to the problem of power calculations for 1 :K matched case-control studies which is related to, but formally outside of, the generalized linear model framework.
From a Relational Approach: The Persuasiveness of Advertisements Endorsed by Celebrities and Online Influencers

Abstract Celebrity endorsement is a commonly used advertising strategy in China. The entertainment and sports industries frequently employ celebrities to do promotions. The development of new media has led to the emergence of self-made micro-celebrities, termed ‘online influencers’. However, most studies analyze the advertising persuasiveness of either celebrities or online influencers separately. Only a limited number of studies compare celebrity endorsement from the perspective of both celebrities and online influencers, and none of them analyze advertising persuasiveness from a relational approach. A cross-sectional survey was conducted with 435 respondents in China. Results indicated that respondents’ perception of celebrities was more positive than online influencers. Furthermore, the motivation driving the relationship was different between celebrity endorsers and online influencers. Insights for strategic marketing engagement were drawn from the results.
Invariance of cohomology groups under a deformation of an elliptic system of linear differential equations

M. Sato has recently proposed to study a "deformation" of systems o linear differential equations in connection with some physical problems (Sato et al. [5], Schlesinger [6]). The purpose of this note is to show theorem concerning the invariance of cohomology groups under the deformation of a system in the sense specified in the theorem below. ) All equations considered in this note are supposed to be with analytic coefficients. Theorem. Let M be a compact real analytic manifold. Let g(t) be an elliptic system of linear differential equations defined on M with a parameter t running over an open interval I of R. Assume that (t) is deformed with respect to t in the following sense: There exists a system of linear differential equations defined on I M such that {t=t0} M is non-characteristic with respect to and that its tangential system to induced on {t=t0}M coincides with l(to) for any to in I. Then ( 1 ) Ext (M; (t),)Ext (M; q(t’),) holds for any t, t’ e I and any ]. Here denotes the sheaf of hyperfunctions on M. Proof. Since t---(t) is elliptic, itsel is elliptic. Hencea result o Kawai [3] claims that ( 2 ) Ext (I’ M; ,n)-Ext (I" M; ,) holds or any ] and ny open intervals I’ and I" with I’ cI" cR. Actually they are known to be finite-dimensional vector spaces over C. (See e.g. Guillemin [1], Kawai [3], Kuranishi [4] and reerences cited there.) Note also that the ellipticity of entails that ( 3 ) Ext (I’ M; ,)-Ext (I’ M ,) holds or any ] and any open set I’cI. Here denotes the shea of real analytic unctions on R M.
Response of Sowing Dates, Crop Establishment Methods and Mulching on Growth, Productivity and Profitability of Spring Wheat at Rampur, Chitwan, Nepal

Intensive tillage with no crop residue after rice harvest in conventional wheat cultivation increases the turn around time, delays sowing and affects the yield. A field experiment was carried out to assess the effect of sowing dates, establishment methods and mulching and their interaction on growth, productivity and profitability of spring wheat at agronomy farm of AFU, Rampur Chitwan, Nepal from November 2020 to April 2021. The experiment was laid out in strip-split plot design, with three dates of sowing (20th November, 5th December and 20th December) in vertical plots, two establishment methods (Zero tillage and Conventional tillage) in horizontal plots and two levels of mulching (0 t ha-1 and 5 t ha-1 of rice straw mulch) in sub-plots and replicated thrice with Vijay as test variety. Data regarding the phenology, growth parameters, yield attributes and yield were recorded, analyzed and presented. The research results revealed that date of sowing and mulching significantly influenced phenology, growth, yield attributes, yield and their interactions. The higher grain yield was obtained in 5th December as well as 20th November sowing in conventional tillage with mulch (4511.49 & 4492.12 kg ha-1 respectively). These grain yields were statistically at par with 5th December and 20th November sowing in zero tillage with mulch (4363.74 & 4129.97 kg ha-1 respectively). Net return and B:C ratio were significantly higher on 5th December and 20th November sowing with mulch in zero tillage than 20th December sowing in conventional tillage without mulch. Int. J. Appl. Sci. Biotechnol. Vol 10(4): 237-244.
Use of International Criticality Safety Benchmark Evaluation Project Data for Validation of the ABBN Cross-Section Library with the MMK-KENO Code

Abstract The ABBN-93 299-group cross-section library is used as a source of neutron data for criticality calculations with the MMK-KENO Monte Carlo criticality code. Validation of criticality calculations is performed using the data presented in the “International Handbook of Evaluated Criticality Safety Benchmark Experiments. ” This paper contains a description of a validation method based on statistical analysis of discrepancies between calculated and benchmark-model keff’s and the results of this validation for different types of experiments. Another validation method using a well-known procedure of group cross-section adjustment based on the maximum likelihood method (generalized least-squares method) and results of the validation for water-moderated highly enriched uranium homogeneous critical systems using selected experiments of the HEU-SOL-THERM type are also presented.