Miracle-dz/UniFAR-FTUs huggingface dataset:
Supervisory styles and graduate student innovation performance: The mediating role of psychological capital and the moderating role of harmonious academic passion

Supervisory styles Are Key predictors of graduate students’ innovation performance (GSIP), but the mediating and moderating mechanisms underlying this relationship require further exploration. Based on the job demands-resources model and conservation of resources theory, this study analyzed the influence of supervisory styles on GSIP, including the mediating role of psychological capital (PsyCap) and the moderating role of harmonious academic passion (HAP). Questionnaires were completed by 400 graduate students from a Chinese university. The results indicated that (1) both supportive and directive supervisory styles (SSS and DSS) were positively related To GSIP, (2) PsyCap fully mediated the relationship between SSS and GSIP, and (3) HAP significantly moderated the effect of DSS but exhibited no moderating influence on the effect of SSS. These findings contribute to a deeper understanding of why, how and when supervisory styles influence GSIP. Implications for both theory and practice as well as the limitations of this research are discussed.
A monte carlo computer study of the power properties of six distribution-free and/or nonparametric statistical tests under various methods of resolving tied ranks when applied to normal and nonnormal data distributions

A study of the power properties of six nonparametric/distribution-free statistics was conducted via computer simulations using Monte Carlo techniques. These statistics utilized rank based procedures and shared an underlying assumption of population continuity such that samples were assumed to have no equal data values (zero difference scores, tied ranks). This assumption is almost never met in practice, however, especially with data in the social and behavioral sciences. The properties of such tests, in particular their power to detect real effects when they exist, is altered under such conditions compared to their theoretical performance when underlying assumptions are met. The nature and extent of these departures are often mathematically intractable, depending on complex interactions of particular combinations and degrees of violation. These tests have not been as extensively studied under violation of their assumptions as they need to be. Both theoretical and empirical data distributions were used for sampling, including the normal distribution for reference. Four of the distributions described by Micerri (1986, 1989) as being typical of the data found in social and behavioral science were used as the source of discrete, nonnormal data. Pure location shift effects were introduced, with integral amounts of shift for the Micceri (1986, 1989) distributions in order to get equal data values between groups. A number of methods for dealing with this situation have been suggested in the literature, but there are few empirical studies. This study looked at various methods for dealing with equal data values (tied ranks). The best overall results, across all tests and combinations of simulation parameters, were obtained by randomly resolving ties. The method of dropping ties and reducing the sample size performed very poorly and should be avoided. The pattern and occurrence of ties was also investigated, along with sampling adequacy. Critical values and associated probabilities were also generated for four of the tests.
The not so hidden impact of interictal burden in migraine: A narrative review

Migraine is a highly prevalent neurological disease of varying attack frequency. Headache attacks that are accompanied by a combination of impact on daily activities, photophobia and/or nausea are most commonly migraine. The headache phase of a migraine attack has attracted more research, assessment tools and treatment goals than any other feature, characteristic, or phase of migraine. However, the migraine attack may encompass up to 4 phases: the prodrome, aura, headache phase and postdrome. There is growing recognition that the burden of migraine, including symptoms associated with the headache phase of the attack, may persist between migraine attacks, sometimes referred to as the “interictal phase. ” These include allodynia, hypersensitivity, photophobia, phonophobia, osmophobia, visual/vestibular disturbances and motion sickness. Subtle interictal clinical manifestations and a patient's trepidation to make plans or commitments due to the unpredictability of migraine attacks may contribute to poorer quality of life. However, there are only a few tools available to assess the interictal burden. Herein, we examine the recent advances in the recognition, description, and assessment of the interictal burden of migraine. We also highlight the value in patients feeling comfortable discussing the symptoms and overall burden of migraine when discussing migraine treatment needs with their provider.
Evolutionary history and patterns of geographical variation, fertility, and hybridization in Stuckenia (Potamogetonaceae)

Aquatic plant species are often widespread, even across continents. They pose a challenge to species delimitation and taxonomy due to their reduced morphology and high phenotypic plasticity. These difficulties are even more pronounced in the case of interspecific hybridization. We investigate the aquatic plant genus Stuckenia for the first time on a worldwide scale. Expert species determination is aided by sequencing of nuclear ribosomal ITS and 5S-NTS regions and the plastid intergenic spacers rpl20-5’rps12 and trnT–trnL. Nuclear markers are used to infer hybridization, and the maternal origin of hybrids is addressed with plastid markers. Pure species are subjected to phylogenetic analyses. Two main Stuckenia lineages are found: one consists of S. amblyphylla, S. filiformis, S. pamirica, and S. vaginata, the other includes S. pectinata and S. striata. The widespread species S. pectinata, S. filiformis, and S. vaginata show intraspecific genetic variation, which is structured geographically. Many intraspecific hybrids, which are usually fertile, occur between those genotypes. Interspecific hybrids, which are consistently sterile, are detected among all widespread species; some are reported for the first time in several countries and regions. They originated multiple times from reciprocal crosses and reflect the geographical origins of parental genotypes. Intraspecific genetic variation can be higher than interspecific differences between closely related species. Comparison of phenotypic variation in the field and in cultivation with genotypic variation shows that numerous conspicuous forms have been overestimated taxonomically. These are resolved as phenotypes responding to unusual environments, have recurrently evolved adaptations, or represent extreme forms of continuous variation of the recognized species. However, some specific regional lineages, which have evolved from variable species, may be interpreted as early steps of the speciation process. Hybridization has been underestimated in some regions as a source of Stuckenia diversity, and the respective hybrid plants have been misidentified as intraspecific taxa or even as separate species. Many erroneous entries in sequence databases are detected and summarized. This work provides a sound basis for species delimitation and hybrid recognition in this difficult genus.
Different genotype and a liquid whey-supplemented diet influence the resilience of pigs through immune-modulation and anti-inflammatory response

This study evaluated (i) whether weight gain and levels of inflammatory and immune markers including white blood cells (WBC), serum haptoglobin, C-reactive protein, albumin, and globulin fractions change between the Nero Siciliano pig breed and the crossbreed Landrace x Large White (LxLW) reared under the same environmental and farming conditions; and (ii) whether a liquid whey diet supplementation affects the investigated parameters in both genotypes. In this study, 10 crossbreed LxLW and 10 Nero Siciliano pigs were given control feed, representing the control groups (CTRC and CTRNS), whereas 10 crossbreed LxLW and 10 Nero Siciliano pigs were given control feed supplemented with liquid whey for 2 months, representing the experimental groups (WC and WNS). From each pig, body weight and blood were collected before experimental diet supplementation (T0), and one (T1) and two (T2) months after the start of the diet supplemented with whey. The white blood cell count (WBC), serum haptoglobin, C-reactive protein, total proteins, albumin and globulin fraction concentration were assessed. Two-way analysis of variance showed an increasing trend of body weight both in the control and experimental groups of the two pig genotypes throughout the monitoring period (p < 0.01) without a significant effect of genotype and diet (p > 0.05). The concentration of haptoglobin, β1- and β2-globulins was affected by pig genotype, diet supplementation, and time (p < 0.01). The values of WBC, C-reactive protein, albumin, α-globulins, and A/G ratio were affected by diet supplementation (p < 0.01) and time (p < 0.01) without an influence of genotype (p > 0.05). Nero Siciliano pigs showed lower levels of haptoglobin, β1-globulin, and β2-globulin compared to crossbreed LxLW. Nero Siciliano pigs and crossbred LxLW fed with liquid whey showed lower levels of WBC, haptoglobin, C-reactive protein, α-, β1-, and β2-globulins and higher values of albumin compared to control groups. The results reinforced the hypothesis that autochthonous breeds possess higher resilience to farming conditions when compared to allochthonous breeds. Moreover, an immune-modulatory and an anti-inflammatory power of liquid whey dietary supplementation is suggested probably thanks to its content in natural bioactive substances including anti-inflammatory cytokines and anti-oxidative factors.
Conceptualizing rurality: The impact of definitions on the rural mortality penalty

Background In the U.S., inequality is widespread and still growing at nearly every level conceivable. This is vividly illustrated in the long-standing, well-documented inequalities in outcomes between rural and urban places in the U.S.; namely, the rural mortality penalty of disproportionately higher mortality rates in these areas. But what does the concept of “rural” capture and conjure? How we explain these geographic differences has spanned modes of place measurement and definitions. We employ three county-level rural-urban definitions to (1) analyze how spatially specific and robust rural disparities in mortality are and (2) identify whether mortality outcomes are dependent on different definitions. Methods We compare place-based all-cause mortality rates using three typologies of “rural” from the literature to assess robustness of mortality rates across these rural and urban distinctions. Results show longitudinal all-cause mortality rate trends from 1968 to 2020 for various categories of urban and rural areas. We then apply this data to rural and urban geography to analyze the similarity in the distribution of spatial clusters and outliers in mortality using spatial autocorrelation methodologies. Results The rural disadvantage in mortality is remarkably consistent regardless of which rural-urban classification scheme is utilized, suggesting the overall pattern of rural disadvantage is robust to any definition. Further, the spatial association between rurality and high rates of mortality is statistically significant. Conclusion Different definitions yielding strongly similar results suggests robustness of rurality and consequential insights for actionable policy development and implementation.
A systematic observational study of radio properties of H2O megamaser Seyfert-2 galaxies

A systematic study is performed on radio properties of H$_{2}$O megamaser host Seyfert 2 galaxies, through multi-band radio continuum observations (at 11cm, 6.0 cm, 3.6 cm, 2.0 cm and 1.3 cm) with the Effelsberg 100-m radio telescope within a total time duration of four days. For comparison, a control Seyfert 2 galaxy sample without detected maser emission was also observed. Spectral indices were determined for those sources for which measurements exist at two adjacent bands assuming a power-law dependence S$_\nu \propto \nu^{-\alpha}$, where S is the flux density and $\nu$ is the frequency. Comparisons of the radio continuum properties between megamaser and non-masing Seyfert 2s show no difference in spectral indices. However, a difference in radio luminosity is statistically significant, i.e. the maser galaxies tend to have higher radio luminosities by a factor of 2 to 3 than the non-masing ones, commonly reaching values above a critical threshold of 10$^{29}$ ergs$^{-1}$Hz$^{-1}$. This result confirms an earlier conclusion by Zhang et al. (2012), but is based on superior data with respect to the time interval within which the data were obtained, with respect to the observational facility (only one telescope used), the number of frequency bands.
Characteristics of the school adaptation of college freshmen during the COVID-19 epidemic

Few studies have actually explored the impact of the COVID-19 pandemic on mental health in college students, although many studies have suggested that the COVID-19 pandemic poses a great threat to people’s mental health in many cohorts. Furthermore, college students may be a particularly vulnerable cohort that needs more attention and access to psychological services due to the psychological changes involved in the transition to college and the characteristics of college students’ study habits and lifestyle. Therefore, investigating the basic characteristics of the impact of the COVID-19 pandemic on college freshmen is of great practical importance and has theoretical implications for the identification and provisioning of services to vulnerable cohorts. A total of 5,818 college freshmen completed the College Student Adaptability Inventory. The results suggest that the mean detection rate of the seven dimensions of undergraduate maladjustment to university is 27.13%. Specifically, livelihood self-management adaptability has the highest detection rate (48.93%), while environmental general evaluation has the lowest detection rate (9.81%). Moreover, the school adaptation of college freshmen is impacted by gender, number of siblings, and family socioeconomic status (SES). Specifically, students who are female, an only child, and have a lower SES have lower levels of school adaptation. However, the school adaptation of college freshmen is not influenced by minority status or left-behind status. The findings of the present study suggest that the maladaptation of college freshmen has been a common phenomenon in China during the COVID-19 epidemic. Prevention programs may be most helpful if they pay more attention to effective intervention efforts for students who are female, an only child, and have a lower SES.
Coordination processes in partnerships between German governmental organizations and German sports federations in jointly implemented SDP projects

Sports and physical activity are increasingly used as instruments of development policy. Within this field of sport for development and peace (SDP), one can observe a large number of partnerships between national governmental organizations and national sport federations. These are particularly important although these organizations pursue different core objectives with their SDP engagement. The aim of this qualitative study is to analyze how German governmental organizations and sports federations coordinate jointly managed SDP projects. Against the backdrop of systems theory, we conducted interviews with participants from relevant organizations. The qualitative content analysis revealed that inter-organizational coordination takes place partly in hierarchical and partly in network-based structures. The results show complex patterns between the participating organizations which gain varying degrees of influence on the SDP projects and seek to get specific resources through the cooperations. These should be taken into consideration when designing SDP projects to build stable cooperations that bring all the participating organizations an added value.
Exploring the pathogenesis of age-related macular degeneration: A review of the interplay between retinal pigment epithelium dysfunction and the innate immune system

Age-related macular degeneration (AMD) is a leading cause of irreversible vision loss in the older population. Classical hallmarks of early and intermediate AMD are accumulation of drusen, a waste deposit formed under the retina, and pigmentary abnormalities in the retinal pigment epithelium (RPE). When the disease progresses into late AMD, vision is affected due to death of the RPE and the light-sensitive photoreceptors. The RPE is essential to the health of the retina as it forms the outer blood retinal barrier, which establishes ocular immune regulation, and provides support for the photoreceptors. Due to its unique anatomical position, the RPE can communicate with the retinal environment and the systemic immune environment. In AMD, RPE dysfunction and the accumulation of drusen drive the infiltration of retinal and systemic innate immune cells into the outer retina. While recruited endogenous or systemic mononuclear phagocytes (MPs) contribute to the removal of noxious debris, the accumulation of MPs can also result in chronic inflammation and contribute to AMD progression. In addition, direct communication and indirect molecular signaling between MPs and the RPE may promote RPE cell death, choroidal neovascularization and fibrotic scarring that occur in late AMD. In this review, we explore how the RPE and innate immune cells maintain retinal homeostasis, and detail how RPE dysfunction and aberrant immune cell recruitment contribute to AMD pathogenesis. Evidence from AMD patients will be discussed in conjunction with data from preclinical models, to shed light on future therapeutic targets for the treatment of AMD.
An enigmatic beetle with affinity to Lamingtoniidae in mid-Cretaceous amber from northern Myanmar (Coleoptera: Cucujoidea)

An enigmatic cucujiform beetle, Alloterocucus atratus Li, Leschen, Liu, and Cai gen. et sp. nov., is reported from mid-Cretaceous Burmese amber. The character combination of the new fossil is not completely consistent with any of the known cucujoid or erotyloid families. Based on our phylogenetic analyses, Alloterocucus is assigned to Cucujoidea and may be allied to Lamingtoniidae, which contains a single Australasian genus in the extant fauna. Alloterocucus shares with Lamingtoniidae a similar habitus and a series of characters, including the absence of postocular constriction, 3-segmented antennal club, externally open procoxal cavities, laterally open mesocoxal cavities, exposed pro- and mesotrochantins, and the absence of epipleural fovea and pronotal setose cavities, but differs from extant Lamingtoniidae in its apically truncate terminal maxillary palpomeres, 5-5-4 tarsi in male and absence of distinct dorsal punctation. Zoobank registration [https://zoobank.org/], identifier [111CE15E-5B49-4154-9E4A-7B3A738C6D2A].
Cpd-42 protects against calcium oxalate nephrocalcinosis-induced renal injury and inflammation by targeting RIPK3-mediated necroptosis

Calcium oxalate (CaOx) crystals, as the predominant component of human kidney stones, can trigger excessive cell death and inflammation of renal tubular epithelial cells, involved in the pathogenesis of nephrocalcinosis. Necroptosis mediated by receptor-interacting protein kinase 3 (RIPK3) serves a critical role in the cytotoxicity of CaOx crystals. Here, we assessed the therapeutic potential of a novel RIPK3 inhibitor, compound 42 (Cpd-42), for CaOx nephrocalcinosis by comparison with dabrafenib, a classic RIPK3 inhibitor. Our results demonstrated that Cpd-42 pretreatment attenuated CaOx crystals-induced renal tubular epithelial cell (TEC) injury by inhibiting necroptosis and inflammation in vitro and in vivo. Furthermore, in an established mouse model of CaOx nephrocalcinosis, Cpd-42 also reduced renal injury while improving the impaired kidney function and intrarenal crystal deposition. Consistent with this finding, Cpd-42 was confirmed to exhibit superior inhibition of necroptosis and protection against renal TEC injury compared to the classic RIPK3 inhibitor dabrafenib in vitro and in vivo. Mechanistically, RIPK3 knockout (KO) tubular epithelial cells pretreated with Cpd-42 did not show further enhancement of the protective effect on crystals-induced cell injury and inflammation. We confirmed that Cpd-42 exerted protective effects by specifically targeting and inhibiting RIPK3-mediated necroptosis to block the formation of the RIPK1-RIPK3 necrosome. Taken together, targeted inhibition of RIPK3-mediated necroptosis with Cpd-42 may provide a potential therapeutic approach for CaOx nephrocalcinosis.
The effects of anesthesia methods and anesthetics on postoperative delirium in the elderly patients: A systematic review and network meta-analysis

Study objective Postoperative delirium (POD) is one of the serious postoperative complications in elderly patients, which is always related to long-term mortality. Anesthesia is often considered a risk factor for POD. This systematic review and network meta-analysis (NMA) aimed to assess the impact of different anesthesia methods and anesthetics on POD. Measurements We searched for studies published in PubMed, Embase, Web of Science, Scopus, and Cochrane Library (CENTRAL) from inception to 18 March 2022. RevMan 5.3 and CINeMA 2.0. 0 were used to assess the risk of bias and confidence. Data analysis using STATA 17.0 and R 4.1. 2. STATA 17.0 was used to calculate the surface under the cumulative ranking curve (SUCRA) and provide network plots with CINeMA 2.0. 0. NMA was performed with R 4.1. 2 software gemtc packages in RStudio. Main results This NMA included 19 RCTs with 5,406 patients. In the pairwise meta-analysis results, only regional anesthesia (RA) with general anesthesia (GA) vs. GA (Log OR: –1.08; 95% CI: –1.54, –0.63) were statistically different in POD incidence. In the NMA results, there was no statistical difference between anesthesia methods, and psoas compartment block (PCB) with bupivacaine was superior to the desflurane, propofol, sevoflurane, and spinal anesthesia with bupivacaine of POD occurrence. Conclusion Our study indicated that RA and GA had no significant effect on POD, and there was no difference between anesthesia methods. Pairwise meta-analysis showed that, except for RA with GA vs. GA, the rest of the results were not statistically different. Besides, PCB with bupivacaine may benefit to reduce POD incidence. Systematic review registration https://www.crd. york.ac. uk/prospero/dis play_record. php? ID=CRD42022319499, identifier PROSPERO 2022 CRD42022319499.