Miracle-dz/UniFAR-FTUs huggingface dataset:
Exploration of Patient Variables and Characteristics Best Suited for Medical Marijuana Treatment for Anxiety and Depressive Disorders

Individuals with posttraumatic stress, anxiety and depressive disorders are currently being prescribed medical marijuana as a treatment in many states across the United States. However, marijuana is still considered a schedule one narcotic by the Drug Enforcement Administration and federal government, which provides several barriers and challenges to conduct research such as approval from the U.S. Food and Drug Administration and following guidelines from the National Institute on Drug Abuse issued by the DEA. Additionally, individuals prescribed medical marijuana for mental health disorders are not always thoroughly instructed on the type of medical marijuana, the dosage, and how frequently to use marijuana. This literature review’s objective was to understand what mental health symptoms medical marijuana treats and what factors indicate medical marijuana is a suitable treatment for posttraumatic stress disorder, anxiety, and depression. Cannabidiol and tetrahydrocannabinol have been found to contribute to an acute reduction in both posttraumatic stress disorder and anxiety symptoms, although longterm efficacy is still unclear. Results have varied with depressive disorders regarding the successful reduction of depressive symptoms. Conversely, studies have shown that medical marijuana and recreational marijuana use may exacerbate depressive symptoms and psychosis, and tetrahydrocannabinol-based medical marijuana products may not be best suited for individuals with a history of substance abuse due to potential habit-forming qualities. In addition, medical marijuana can have an impact on the concentration of psychotropic medications. Studies to date have indicated that medical marijuana’s effective dosage for treatment may differ across individuals depending on the disorder, individual factors, prior marijuana use, and time relative to experience symptoms.
PGPM_A_274741 117..133

1Núcleo de Pesquisas em Oncologia, Universidade Federal do Pará, Belém, Pará, Brazil; 2Departamento de ensino e pesquisa, Hospital Ophir Loyola, Belém, Pará, Brazil; 3Grupo de Medicina Xenómica, Centro Nacional de Genotipado (CEGENPRB3), Universidade de Santiago de Compostela, Santiago de Compostela, España; 4Unidad de Genética Clínica y Genómica Funcional, Departamento de Farmacología-Fisiología, Escuela de Medicina, Universidad de Zaragoza, IISAragón, E-50009 Zaragoza, España; 5Centro de Investigación Biomédica en Enfermedades Raras (CIBERER), Grupo de Medicina Genómica, CIMUS, Universidad de Santiago de Compostela, Santiago de Compostela, España; 6Laboratório de Genética Humana e Médica, Universidade Federal do Pará, Belém, Pará, Brazil; 7Fundación Pública de Medicina Xenómica, Instituto de Investigación Sanitaria de Santiago de Compostela (FIDIS), Universidade de Santiago de Compostela, Santiago de Compostela, España Introduction: The genetic admixture of the Brazilian population has considerable relevance to the implementation of the principles of pharmacogenomics (PGx), as it may compromise the extrapolation of data obtained in more homogeneous world populations. Purpose: This study aims to investigate a panel of 117 polymorphisms in 35 pharmacogenes, which contains label recommendations or clinical evidence by international drug regulatory agencies, in Amazonian Native American populations, and compare the results obtained with continental population data from the 1000 Genomes Project Consortium. Patients and Methods: The study population is composed of 109 Native American individuals from three Brazilian Amazon groups. The genotyping of the PGx polymorphisms was performed by allelic discrimination using TaqMan OpenArray Genotyping with a panel of 120 customized assays on the QuantStudioTM 12K Flex Real-Time PCR System. Results: Statistical differences within the Native American populations were observed regarding both genotypes and phenotypes of some genes of the CYP family. The discriminant analysis of principal components (DAPCs) between the NAM group and the continental populations of the 1000 Genomes Project resulted in the clustering of the three Native American populations. Additionally, in general, the NAM group was determined to be closely situated between East Asia, America, and South Asia groups, which enabled us to infer a genetic similarity between these populations. The DAPC analysis further demonstrated that eight polymorphisms and six polymorphisms were more relevant in differentiating the NAM from the continental populations and the NAM populations among themselves, respectively. Conclusion: Some investigated polymorphisms show differences among world populations, particularly with populations of European origin, for whom precision medicine protocols are primarily designed. The accumulated knowledge regarding these variations may assist in the design of specific protocols for Native American populations and populations admixed with them.
Engine performance and PM concentrations from the combustion of Iraqi sunflower oil biodiesel under variable diesel engine operating conditions

The most desirable alternative fuels are biodiesel among several of alternative fuels to use in diesel engines. The biodiesel used in this study is sunflowers oil which derived from local renewable sources. Also, biodiesel considered a best alternative to conventional diesel because it clean and environment friendly. The experimental results shown that the biodiesel blends (B20, B50, and B100) increased the brake specific fuel consumption (BSFC) compared with pure diesel fuel. According to the results, it is indicated that the biodiesel blends reduced the brake thermal efficiency (BTE) and exhaust gas temperatures (EGT) during the combustion of B20, B50, and B100 for all engine operating conditions. The exhaust gas temperature and BSFC increased with increase the operating conditions of engine loads and speeds. The data indicated that PM concentrations reduced with biodiesel blends combustion compared with diesel under variable engine loads and speeds. Besides that the concentrations of PM reduced by 16.847, 28, and 43.34% combustion of B20, B50, and B100, when compared with petroleum diesel under the same conditions of engine loads and speeds. The results give insight that the oxygen content in the biodiesel has favourable effect on reducing the PM concentrations.
Assessment of Pain Intensity among Preschool-age Children during Venipuncture

Background: Venipuncture is a devastating medical, emotional, and physical problem for pediatric patients and their families. Blood drawing is one of the most frightening and distressing nursing procedures for hospitalized children. Aim: To assess pain intensity among preschool children during venipuncture. Research design: A descriptive research design was used in the current study. Sample included 60 preschool-age children undergoing venipuncture procedures over six months. Setting of the study: - Pediatric medical unit at Minia University Hospital for Obstetrics and Pediatrics. Tools: Tool (I): structured interview questionnaire which developed by the researcher Tool (II): Wong-Baker Faces Pain Rating Scale Tool (III): Children's Hospital of Eastern Ontario Pain Scale (CHEOPS). Results: The highest percentage of the studied preschool-age children experienced severe pain during venipuncture procedure according Wong-Baker Faces Pain Rating Scale. The total mean scores of Wong-Baker Faces Pain Rating Scale and Children's Hospital of Eastern Ontario Pain Scale were high markedly during venipuncture. There were statistically significant negative correlations between children's age and the total mean scores of the CHEOPS and Face Pain Rating Scale during venipuncture. Conclusion: it was concluded that preschool-age children complained from severe pain intensity during venipuncture procedure. Recommendation: An educational training program is mandatory for pediatric nurses about pain assessment and pain management strategy during venipuncture and other painful procedures.
Effect of Melatonin on the efficacy of Chloral hydrate in Sedating Children Undergoing Auditory Brainstem Response Test: A controlled randomized clinical trial

Background: To obtain an accurate diagnosis, children with hearing impairment could be examined by auditory brainstem response test. Young children are usually uncooperative and could not be examined without sedation. The most commonly used sedative is chloral hydrate. Some investigators used melatonin as an alternative sedative. Our study aimed to evaluate the effect of melatonin as adjuvant when added to chloral hydrate. Methods: The study was conducted at the Clinic for Hearing, Balance and Communication, Mosul, Iraq, from July to December 2018, and has been approved by the regional Research Ethics Committee with a design of the un-blinded randomized clinical trial. Parents provided a written informed consent. Two hundred and fifty-four children aged 8 months-7 years attending for auditory brainstem response test were allocated randomly to two groups. The group A children as controls (n=150), were receiving chloral hydrate oral dose 50mg/kg, while the group B cases (n=104), were receiving melatonin 0.1mg/kg plus chloral hydrate 50mg/kg. Both groups were compared in sleep latency, success rate of sedation within 30 minutes, as well as sleep duration. Relative risk (RR), t-test and chi-square were used. Results: Within 30 minutes of the initial dose intake, the group of the combined melatonin and chloral hydrate achieved a higher success rate in the sleep induction than the group of the chloral hydrate, (n=98, 94.2% versus n=112, 74.6%), RR=1.262, P<0. 001. Conclusion: Melatonin could enhance the efficacy of chloral hydrate when added to it, as an adjuvant agent.
Effects of garlic supplementation on in vitro nutrient digestibility, rumen fermentation and gas production.

Garlic contains secondary metabolites with antimicrobial properties that can alter nutrient digestibility and rumen fermentation, similar to other antimicrobial products. The objectives of the study were to evaluate the effects of garlic powder and garlic juice on in vitro nutrient digestibility, rumen fermentation, and gas production. The treatments consisted of control with no additives, garlic powder, and garlic juice at 0.5 ml and 1 ml. The digestibility of dry matter, crude protein and neutral detergent fibre were determined after 48 hours incubation. Rumen ammonia nitrogen and volatile fatty acids were determined at 12 hours and 24 hours incubation. The cumulative gas production was recorded periodically over 48 hours. The in vitro dry matter disappearance decreased with 1 ml of garlic juice compared with control. The crude protein degradability in garlic powder and garlic juice was lower than in control. Volatile fatty acids increased in all treatments. Individual volatile fatty acids were significantly different, especially propionate, whereas the acetate to propionate ratio was reduced by garlic juice, and ammonia nitrogen was reduced by garlic powder and 0.5 ml of garlic juice. The cumulative gas production increased significantly with both levels of garlic juice. The addition of garlic juice at 0.5 mL/100 ml could enhance the production of propionate, and reduce the acetate to propionate ratio, implying that the supply of hydrogen for methanogens was limited. ______________________________________________________________________________________
External factors affecting the adoption of IoT-Technology: A TAM and UTAUT approach

This research is conducted for analyzing the digitization process of a company, by investigating the role of IoT technology as a strategic tool. The core purpose is to identify factors influencing a company’s motivation for implementing IoT into its strategic plans and to gain a better understanding of the technology’s potential in general as a strategic option. This exploratory study strives for outlining the dynamics of a company's environment, potentially affecting the decision-making process with regard to IoT implementation. To do so, the ‘Unified Theory of Acceptance and Use of Technology' (UTAUT) is applied and expanded, intending to conceptualize a model that merges the identified factors. Besides studying secondary sources, represented by existing literature about digitization and IoT technology, primary data is collected in form of three interviews, leading to an evaluation of the complex topic from three different perspectives. The findings highlight the complexity of the topic, by emphasizing the IoT technology dependence on the global motivation to create a digitized
Watershed basins delineation using GIS and Digital Elevation Model (DEM) to the region NI-38-14 Karbala-Al-Najaf Plateau, Iraq

The available watersheds in the vast lands need extraction and determination in order to benefit from them and estimate the quantities of water supplied by these watersheds. The satellite image is uploaded to the NI-38-14 Karbala-Al-Najaf plateau from the USGU website in the form of a Digital Elevation Model (DEM). GIS technology is used to calculate the morphometric properties and output them in the form of tables and cartographic models. The water networks of the geographical plateau NI-38-14 located between the administrative borders of the provinces of Al-Najaf and Karbala in Iraq are devised by extracting a topographic map of the area and calculating the areas of the watersheds and their perimeters. The topographic map showed great variations in the level of the earth’s surface, as the heights of the area ranged between 20m and 120m. The number of watersheds extracted in the Karbala-Al-Najaf plateau is 150 watersheds with different areas, the large area is about 4882 km2, while the small area is about 1 km2, and between those areas there are various areas. The largest recorded watershed circumference reached 580km in area (4882 km2), while the lowest recorded perimeter is 8km for the area (1 km2).
Elements of Cartesian Analysis in Saidou Spaces

The objective of this research paper is to follow up on the work already started in order to install a new mathematical analysis, the one we called Cartesian analysis see our previous works[1],[2]. During these last two papers, we started with the definition of cartesian geometry and we defined and introduced to a new Cartesian topology which gave birth to new spaces called Saidou spaces. Thus, and to follow up on this way, we propose to studie the analytical and functional part of this analysis. We will define the notion of a Cartesian function and then its epigraph before to characterize the analytical properties of these functions, for example the continuity and the differentiablity. In an other hand, we will see the relationship between cartesian functions and the convex functions. According to the latest papers and this work we do the asset of the first foundations of the cartesian analysis.
Effect of Adding Magnesium Oxide Nanoparticles on the Antimicrobial Activity of a Denture Soft Liner

Microbial growth and colonization are one of the disadvantages after the long-term use of denture soft liners. This study was aimed to evaluate the effect of the addition of magnesium oxide nanoparticles (MgONPs) on the antimicrobial activity of a denture soft liner. A total of 84 samples were prepared from a soft denture liner and divided into two groups, control group and test group to which 3% by weight of MgONPs were added, antimicrobial tests for Candida albicans, Staphylococcus aureus, and a mixture of the biofilm of both microorganisms were done, cell density count and adherence assay test was recorded before and after 6 months storage in distilled water. The results showed that the modified group performed a better antimicrobial activity compared to the control group, the addition of 3% of the nanofiller showed a significant reduction in the mean value of growth of both C. albicans, S. aureus, and the biofilm mixture (P < 0.05) before and after the storage period. In conclusion, the addition of 3% by weight of MgONPs to the denture soft liner significantly suppressed the growth of C. albicans, S. aureus up to 6 months.
Bacterial Contamination of Mobile Phones Carried by Medical Staff in Maternity, Neonatal, and ICU Wards of Shahid Beheshti and Imam Sajjad Hospitals in Yasuj

The use of mobile phones by healthcare personnel, doctors, patients, and patients’ companions are unavoidable in health centers, especially in hospitals. Besides being rarely clean, the mobile phone is a potential reservoir of disease and pathogens and hospital infections on bedside of hospitalized patients. In this study, the microbial contamination of mobile phones and potential of transmitting infections and their antibiotic resistance pattern were investigated. In this descriptive cross-sectional study, a questionnaire was prepared to assess the importance of maternity, neonatal, and intensive care unit (ICU) staff attention to how to use and clean the cell phones in terms of valid sources. Samples were taken from 116 cell phones using a sterile swab. The standard plate count was used to detect the existing bacteria, and the antimicrobial resistance patterns of isolated bacteria were determined by standard methods. The microbial culture experiments indicated that 107 cell phones had microbial contamination, accounting for 92.24% of mobile phones. From 132 isolated strains, 115 strains (87.12%) were gram-positive while 17 were Gram-negative (12.88%). Furthermore, 67 (57.76%), 9 (7.7%), 4 (3.45%), 10 (8.62%), 12 (10.35%), 22 (19%), and 8 (6.9%) strains were coagulase-negative staphylococci, Pseudomonas aeruginosa, Staphylococcus aureus, Corynebacterium, Bacillus, Streptococcus, and Escherichia coli, respectively. The results of this study indicated that cell phones were contaminated with different types of bacteria, and that all species isolated partially played an important role in the development of hospital-acquired and opportunistic infections. Therefore, continuous disinfection of mobile phones and non-use or limited use of them in the hospitals are recommended.
Acute Kidney Injury in Critically Ill Patients

Introduction: The assumption that critically ill patient is well defined, promptly recognized and immediately transported in to the Intensive Care Unit (ICU), leads to wrong estimations and erroneous viewpoints of critically ill patient’s epidemiology. The «critically ill» definition neither presupposes his admission in ICU nor precludes his hospitalization in the hospital ward. The purpose of the present study was to evaluate the incidence and risk factors of AKI taking into account the totality of critically ill patients of a given time period . Methods: This is a retrospective study conducted in the general ICU of the University hospital “Attikon”. Participants were adult patients in which an intensivist’s consultation was effectuated by the ICU staff, during a period of 2.5 months. The estimated baseline creatinine was calculated using the MDRD formula, assuming a lower limit of normal baseline glomerular filtration ratio (GFR) of 75ml/min/1.73m2. The presence of AKI was assessed only within the first consultation and was stratified by the three RIFLE categories of severity (Risk, Injury and Failure). The impact on disease’s incidence of demographic characteristics, medical history, clinical data and severity scores of the participants was evaluated. Results: A total of 69 critically ill patients were enrolled in the study. The overall incidence of AKI by the time of 1st consultation was 43% with the women being more frequently and more severely affected. The severity score seemed to be the principal independent risk factor for early AKI occurrence. The adjusted risk of AKI, increased by 14% per unit of increase in the APACHE score (OR 1.12CI 95% 1.03-1.21 P=0.008). Conclusion: Severity score is an independent risk factor of AKI in critically ill patients. Identification of high risk patient and early diagnosis is the only available way to prevent the disease and to improve outcomes.
Daddy, How do I Find a Book on Purple Frogs? Representation Issues for Children and Youth

Subject access and controlled vocabularies used for representing children’s resources are examined. Wittgen-stein’s Language Games theory is presented as a possible framework for determining sources to use for controlled vocabulary construction. Preliminary results regarding existing controlled vocabulary use in databases and digital libraries designed for children are presented, as are extent of match ﬁ ndings comparing users’ search terms with LCSH, Sears, and a subject-speciﬁ c proprietary controlled vocabulary are reported.
Peer Support for Dietary Compliance Patients with Diabetes Mellitus

Diabetes mellitus is one of chronic disease whose incidence increases. The success of diabetes mellitus treatment is strongly influenced by patient compliance to carry out treatment. The purpose of this study was to determine the effect of peer support on dietary compliance of diabetes mellitus sufferers at Randu Agung RW X. This study used pre-experiment one-group pre-post test design on sample of 28 diabetes mellitus sufferers in Randu Agung RW X, used purposive sampling technique. The instrument used Satuan Acara Kegiatan (SAK), attendance list, and compliance questionnaire of diabetes mellitus with 3J program. The analysis of the data used the Mc Nemar test. The statistical test results obtained P <0.05 (0.000), it meant H1 was accepted; there was an effect between peer support and dietary compliance in diabetes mellitus sufferers. Peer support is a new technique to control the blood sugar levels of people with diabetes by involving peers who have similar diseases to share experiences, provide support, and motivation so that enthusiasm in running their dietary increases. If someone sees other people successfully controlling their blood sugar levels through good dietary compliance, it will foster that person’s enthusiasm to be able to comply with the diabetes mellitus dietary program. The implication of the study results is that providing education with peer support can help other people in similar situations to increase dietary compliance in diabetes mellitus sufferers.
Comparison of Anopheles cracens (Stenogamous) and Anopheles dirus (Eurygamous) blood-feeding behaviors, survival rates and fecundity after first and second blood meals

Malaria is a serious health problem in Southeast Asia. The malaria vectors Anopheles cracens (Stenogamous) and Anopheles dirus (Eurygamous) were used to evaluate the impact of first and second blood meals on feeding, survival and hatching rates, and fecundity. Females were divided as follows: mated with oviposition, mated without oviposition, and virgin. The blood-feeding rates of An. cracens groups were significantly lower for the second blood meal than for the first. Additionally, for An. dirus mated without oviposition and virgin groups, blood-feeding rates were significantly lower for the second blood meal compared with the first blood meal. Survivorship and the number of eggs laid increased for An. cracens after the second blood meal, but the opposite was true for An. dirus. There were no differences in hatching rates. Thus, blood meals affected survivorship and fecundity in naturally mating An. cracens and induced-mating An. dirus.