Miracle-dz/UniFAR-FTUs huggingface dataset:
Dysregulation of Expression of the FOXO3 Transcription Factors Pathway in Helicobacter pylori Associated Gastric Cancer

The transcription factor FOXO3 acts as a tumor suppressor and is the major target of AKT kinases pathway. The protein encoded by FOXO3, prevents the activation of genes that are important for proliferation, differentiation and death cell. In addition, FOXO3 interacts with BCL-2 family proteins; and among them, BBC3 (PUMA) and BCL2L (BIM) are responsible for regulating apoptosis through the BAX and BAK chains. This study investigated the expression of FOXO3a, BBC3 and BCL2L in gastric cancer considering the presence of Helicobacter pylori and its involvement in the modulation of gene and protein expression. A total of 225 gastric biopsy samples were evaluated from individuals with normal gastric mucosa (n=54), gastritis (n=108), and gastric cancer (n=63), of both genders and over 18 years old. Samples were subclassified according to the presence or absence of Helicobacter pylori, detected by PCR. Real-time quantitative RT-PCR (qRT-PCR) and western blotting, were used to detect the expression. FOXO3 showed increased gene (p<0.0001) and protein (p=0.036) expression in patients with gastric cancer, who also exhibited a boost in mRNA expression through H. pylori infection. BCL2L had a subtle increase in its expression independent of the presence of H. pylori (p<0.0001), while the BBC3 gene showed no alterations. Our results suggested that increase FOXO3 expression may play an important role in carcinogenesis by performing positive feedback in an attempt to eliminate neoplastic cells. FOXO3 could be suggested a prognostic marker as well as a potential molecular therapy target for gastric cancer patients.
Incompatible Graded Finite Elements for Analysis of Nonhomogeneous Materials

A six-node incompatible graded finite element is developed and studied. Such element is recommended for use since it is more accurate than four-node compatible element and more efficient than eight-node compatible element in two-dimensional plane elasticity. This paper presents comparison between six-node incompatible (QM6) and four-node compatible (Q4) graded elements. Numerical solution is obtained from abaqus using UMAT capability of the software and exact solution is provided as reference for comparison. A graded plate with exponential and linear gradation subjected to traction and bending load is considered. Additionally, three-node triangular (T3) and six-node triangular (T6) graded elements are compared to QM6 element. Incompatible graded element is shown to give better performance in terms of accuracy and computation time over other element formulations for functionally graded materials (FGMs).
Scale interactions and spectral energy transfer in turbulent channel flow

Spectral energy transfer in a turbulent channel flow is investigated at Reynolds number $Re_{\unicode[STIX]{x1D70F}}\simeq 1700$ , based on the wall shear velocity and channel half-height, with a particular emphasis on full visualization of triadic wave interactions involved in turbulent transport. As in previous studies, turbulent production is found to be almost uniform, especially over the logarithmic region, and the related spanwise integral length scale is approximately proportional to the distance from the wall. In the logarithmic and outer regions, the energy balance at the integral length scales is mainly formed between production and nonlinear turbulent transport, the latter of which plays the central role in the energy cascade down to the Kolmogorov microscale. While confirming the classical role of the turbulent transport, the triadic wave interaction analysis unveils two new types of scale interaction processes, highly active in the near-wall and the lower logarithmic regions. First, for relatively small energy-containing motions, part of the energy transfer mechanisms from the integral to the adjacent small length scale in the energy cascade is found to be provided by the interactions between larger energy-containing motions. It is subsequently shown that this is related to involvement of large energy-containing motions in skin-friction generation. Second, there exists a non-negligible amount of energy transfer from small to large integral scales in the process of downward energy transfer to the near-wall region. This type of scale interaction is predominant only for the streamwise and spanwise velocity components, and it plays a central role in the formation of the wall-reaching inactive part of large energy-containing motions. A further analysis reveals that this type of scale interaction leads the wall-reaching inactive part to scale in the inner units, consistent with the recent observation. Finally, it is proposed that turbulence production and pressure–strain spectra support the existence of the self-sustaining process as the main turnover dynamics of all the energy-containing motions.
Temi di discussione

As in other industries, competition in banking is potentially beneficial to efficiency and social welfare. Unfortunately, the task of measuring such competition is not straightforward: according to the empirical literature, traditional metrics to measure competition may fail because they do not correctly account for entry barriers, product substitutability, or the concentration and reallocation of market shares among banks. In this study we explore new measurements of competition, based on the Profit Elasticity, which can limit previous drawbacks, in order to assess the significant changes in the Italian banking market over the last two decades (1994-2013), when the most serious crisis occurred. We focus on competition dynamics over time, across bank clusters and geographical areas. Our main findings suggest that deregulation and M&A activity increased the extent of competition, while the financial turmoil reduced it, in line with other international evidence. Moreover, mutual banks faced relatively less competitive local markets, mostly owing to the informational barriers that they can impose on non-local intermediaries, and banking competition is heterogeneous across Italian macro-regions.
THE FISCAL POLICY IMPLICATION OF NON-OIL TAX REVENUE EFFECT ON NIGERIAN ECONOMIC PERFORMANCE

The persistent dependent of Nigerian economy on public debt financing as a panacea to deficit budgetary circumstances and fiscal management had held her attention from adequate exploration in alternative sources of revenue in spite of the long-term implication of debt burden and overhang. Spurred by this scenario, the researchers examined the effect of non-oil tax revenue on economic performance in Nigeria for a period of 2002 to 2019. The study employed company income tax revenue and value added tax revenue as proxies for non-oil tax revenue while Real Gross Domestic Product (RGDP) was used to measure economic performance. Ex post facto research design was adopted for the study. Secondary data were obtained from National Bureau of Statistics (NBS), Central Bank of Nigeria (CBN) and Federal Inland Revenue Services (FIRS). The obtained data were analysed with a specified econometric model and ordinary least square linear regression was employed with the aid of E-views and Statistical Package for Social Sciences (SPSS) version 21 to estimate the residuals. Other diagnostic tests conducted were descriptive statistics of data to ascertain its normality, Stationarity and Co-integration tests by Autoregressive Distributive Lag (ARDL) to ascertain the long run relationship in the model. The results indicated that company income tax revenue has positive and significant effect on real gross domestic product in Nigeria. Similarly, value added tax revenue related positively and significantly with real gross domestic product in Nigeria. Therefore, it was concluded that non-oil tax revenue generated in Nigeria has statistical evidence to stimulate and enhance the economic performance in Nigeria. It was recommended that adequate administrative attention should be accorded the inflow of non-oil tax revenue in Nigeria because it stimulates the needed fiscal resources for governmental functions and attract positive multiplier effect on the economy. Also, the fiscal policy framework of non-oil tax administration should encompass statutory provisions, more incentives and enhanced institutional capacity to discourage tax evasion and avoidance among corporate entities as to properly tap the potentials in Non-oil tax.
Extension of the Semantic Field of the Word ‘Braking’ via the Benvenistien Dialectic ‘Form / Sense’

 Abstract : In this article we try to show the possibility to proceed on one extension of the semantic field of some words as part of didactic communication. This possibility raises questions about the consistency of distinctions benvenistiennes : categories of thought / language categories ' semiotic / semantic ' and ' form / sense.
LINK and the dynamics of utterance interpretation

The operation allows the derivation of inferential units as the result of syntactic processing. The same operation derives structure across a diffuse range of data; the differences between these are attributable to lexical information and the dynamics of the process. The thesis examines a range of data where clauses depend on some element in the main clause for interpretation. These are assigned structure as LINK trees in the framework of Labelled Deductive Systems for Natural Language outlined in Kempson, Meyer-Viol & Gabbay, (Dynamic Syntax: the Deductive Flow of Natural Language, in prep.). I describe the approach to utterance interpretation this proposes: linguistic structure is built incrementally according to lexically encoded procedural instructions and rules of construction constrained by pragmatic principles. This allows a perspective where problems previously divided between syntax, semantics and pragmatics can be addressed in a more unified manner. 1 outline the operation as it has been developed for relative clauses. This allows several trees to be built for the same utterance which are connected by a having a node description in common. I argue that this operation can be extended to cover the following data: extraposed relative clauses, reduced relative clauses, adjunct predicates and parenthetical constituents. To this end I introduce type (p) into the framework, which allows the representation of non-tensed propositions and I modify the operation to allow the creation of trees from discontinuous input. I develop context-dependent lexical rules to capture the difference between modifying and predicative uses of lexical items. The interaction of processing tasks, compilation and lexical information determines the precise nature of the structures which are built. The update procedure I develop allows a uniform characterisation of the way structure is derived across different contexts, shedding new light on the dynamics of building interpretation.
Modeling and Analysis of Piezoelectric Energy Harvesting With Dynamic Plucking Mechanism

Nonharmonic excitations are widely distributed in the environment. They can work as energy sources of vibration energy harvesters for powering wireless electronics. To overcome the narrow bandwidth of linear vibration energy harvesters, plucking piezoelectric energy harvesters have been designed. Plucking piezoelectric energy harvesters can convert sporadic motions into plucking force to excite vibration energy harvesters and achieve broadband performances. Though different kinds of plucking piezoelectric energy harvesters have been designed, the plucking mechanism is not well understood. The simplified models of plucking piezoelectric energy harvesting neglect the dynamic interaction between the plectrum and the piezoelectric beam. This research work is aimed at investigating the plucking mechanism and developing a comprehensive model of plucking piezoelectric energy harvesting. In this paper, the dynamic plucking mechanism is investigated and the Hertzian contact theory is applied. The developed model of plucking piezoelectric energy harvesting accounts for the dynamic interaction between the plectrum and the piezoelectric beam by considering contact theory. Experimental results show that the developed model well predicts the responses of plucking piezoelectric energy harvesters under different plucking velocities and overlap lengths. Parametric studies are conducted on the dimensionless model after choosing appropriate scaling. The influences of plucking velocity and overlap length on energy harvesting performance and energy conversion efficiency are discussed. The comprehensive model helps investigate the characteristics and guide the design of plucking piezoelectric energy harvesters.
2-frugal Coloring of Planar Graphs with Maximum Degree at Most 6

—For a color c in a proper coloring of a graph G , let n c ( v ) denote the times of the color c be used in the neighbors N ( v ) of the vertex v . A t -frugal k -coloring of G is a proper coloring φ : V ( G ) → { 1 , 2 , . , k } such that every vertex v ∈ V ( G ) has n c ( v ) ≤ t for each color c . The minimum number of colors required to ensure that a graph G has a t -frugal coloring is called t -frugal chromatic number of G , denoted by Φ t ( G ) . This paper proved that if G is a planar graph with ∆( G ) ≤ 6 , then Φ 2 ( G ) ≤ 17 . We also gave a linear time algorithm for producing a 2-frugal 17-coloring of a planar graph G without adjacent triangles.
Synthesis and CO 2 Adsorption Capacity of Biomass Waste Functionalized by Nanoparticles

Two composite materials were synthesized based on sodium alginate and biochar derived from licorice processing waste functionalized with silicon dioxide nanoparticles (SiO 2 ) and iron oxide (Fe 2 O 3 ), respectively, enabling the valorization of industrial waste. The adsorptive capacities of the two materials (Alg-SiO 2 and BC L - Fe 2 O 3 ) toward CO 2 in the gaseous stream with nitrogen were evaluated by acid titration of carbonates present in a trap for CO 2 consisting of a KOH solution placed downstream of the adsorption column. The aim of the present work is to evaluate the CO 2 adsorption capacity of material functionalized by nanoparticles. Adams– Bohart, Thomas models, and % removal efficiency curves for the adsorption were examined to investigate the dynamic behavior of the column. From the tests performed in CO 2 and N 2 flow, the BC L -Fe 2 O 3 material was demonstrated to have an adsorbent higher capacity than Alg-SiO 2 , respectively CO 2 adsorbed
Inequality in Marx and Piketty Theory and Policy Implications

This paper explores Piketty’s analytical model in contrast to the classical/Marxian approach. The main point raised herein is that Piketty’s reliance on neoclassical growth theory is not suitable for the explanation of the dynamics of incomes and wealth. However, certain mainstream economists have attempted to attribute the shortcomings of Piketty’s reasoning to some alleged methodological connection with Ricardo and Marx. I argue that Piketty’s theory has nothing to do with the classical political economy and Marx. The latter associates endogenous technology and population growth with unemployment and class struggle in determining the wage and profit share. Recent econometric studies indicate that this approach provides a much more rigorous explanation of the dynamics of inequality. Moreover, contrary to the argument of Piketty, the classical approach suggests that labor can regain what it has lost during the neoliberal era through the class struggle
Aspects of four-dimensional black holes with hair : stability and entropy considerations

In recent years, a large number of black holes have been presented as candidates for an evasion of the "no-hair" conjecture. These examples typically have two features: a non-Abelian gauge field and instability. A large part of this thesis is devoted to a detailed study of the Einstein-Yang-Mills-Higgs (EYMH) black holes, including the analytic proof of the evasion of the "nohair" theorem in this case and proving that the black holes are unstable. We also consider an example of a "hairy" black hole not involving a non-Abelian gauge field, which arises in a higher derivative model of gravity derived from string theory, and prove analytically how the "no-hair" theorem is evaded. The rest of this thesis is concerned with the thermodynamics and quantum field theory of these black holes. In a first order approximation to the unknown theory of quantum gravity, we calculate the entropy of the "hairy" black holes. This turns out to be divergent, and parts of the divergences are attributed to the effect of hair on information loss processes occurring as the black hole evolves in time. We pursue this idea further by making a preliminary estimate of the magnitude of the quantum de-coherence effects on the state of the quantum field as time proceeds. These processes may be of interest phenomenologically in the future. The extension of the theory to non-static geometries is also discussed, by describing the results of bringing rotation into the picture. We prove that the Hartle-Hawking state is not regular everywhere outside the event horizon of a Kerr black hole, with the result that quantum field theory on rotating black hole space-times is more complicated than on static geometries.
Choroidal Granuloma as an Initial Manifestation of Systemic Tuberculosis: A Case Report

Purpose: To describe the presentation and management of presumed ocular tuberculosis, successfully treated with anti-tubercular therapy alone. Case Report: Presumed tuberculous choroidal granuloma associated with serous retinal detachment healed after initiation of antituberculosis therapy without concomitant corticosteroid therapy. Conclusion: Although corticosteroids are often used as add-on treatment for ocular tuberculosis, selected patients can be treated with anti-tuberculosis therapy alone with close follow-up.
Response of magnetized plasma having linearly varying electron density profile to oblique electromagnetic wave incidence

ABSTRACT The response of magnetized plasma slab to obliquely incident electromagnetic wave is determined for different incidence angles and magnetic field intensity values in the case of linearly varying electron density profile along the plasma slab. It is shown that plasma slab provides wide-band absorption due to the proper adjustment of the slope of the electron density profile, incidence angle and magnetic field intensity values. Plasma medium providing wide-band absorption performance under oblique incidence is proposed for military stealth and current shielding applications.
PoliteNess iN earlY PtoleMaiC PaPYri: a FraMe-Based aPProaCH

: this paper deals with the expression of linguistic politeness in early Helle-nistic documentary papyrus letters, through a data-oriented approach exploiting the notion of “frame” (cf. terkourafi 2001), which accounts for politeness in terms of regular correlations between forms and contexts. the study focuses on a subset of epistolary types, i
The Effects of Pranayama or Deep Breathing Exercises on Fatigue and Sleep Quality in Women Receiving Radiation Therapy for Breast Cancer.

OBJECTIVES To evaluate the effects of pranayama and deep breathing exercises on fatigue and sleep quality in women undergoing radiation therapy for breast cancer. SAMPLE & SETTING This randomized controlled study was conducted on the outpatient radiation oncology unit of a hospital with 20 patients each in pranayama, deep breathing, and standard care groups (N = 60). METHODS & VARIABLES The Piper Fatigue Scale and the Pittsburgh Sleep Quality Index were used to evaluate the participants' fatigue and sleep quality. RESULTS The control group showed a significant increase in fatigue levels at the end of radiation therapy compared to the beginning. Sleep quality was improved only in the pranayama group. IMPLICATIONS FOR NURSING Pranayama can be learned easily, can be performed anywhere, and does not require any equipment, making it a convenient exercise for patients. Oncology nurses can take the lead in suggesting pranayama for symptom management.
An improved satellite-based evapotranspiration routine for China

Evapotranspiration (ET) is a critical process that regulates the heat and water transfer between the land and atmosphere. Instantaneous satellite data can provide area-wide daily ET measurements. Surface energy budgets used in satellite-based calculations generally overpredict daily net radiation and the related ET. Our objective was to improve the accuracy of satellite-based daily evapotranspiration by correcting the overprediction of net radiation. To do so, we introduced a routine for calculating the downward longwave radiation on cloudy days. This new algorithm removed the upward bias in the predicted net radiation at seven ChinaFlux sites. Then, using previously developed methods for converting instantaneous measurement into daily averages, we found that evapotranspiration rates were predicted more accurately than existing methods at the same ChinaFlux sites. In addition, our evapotranspiration rates
The acute effect of different frequencies of whole-body vibration on range of motion and jump performance in preadolescent karate athletes

Whole-body vibration (WBV) treatments have acute effects on strength, power, and range of motion (ROM) by affecting the nerve-muscle function. However, there is little evidence about what could be the optimal practice for acute WBV. The purpose of this study is to reveal the acute effects of vibrations applied at different frequencies to preadolescent karate athletes on jump and ROM performance. Forty-six competing preadolescent karate athletes, who trained regularly ( 12.7 ± 1.7 years, 155.2 ± 3.1 cm, 50.9 ± 4.7 kg) and were blue belt and above , were included in the study. Each athlete followed a vibration protocol with four different frequencies (0, 25, 30, and 35 Hz) in random order on nonconsecutive days. After a 5 min light-paced warm-up jog before each protocol, three repetitions of 20 sec (20 sec rest between repetitions) vibration treatments were applied. Jump and ROM tests were carried out after each vibration treatment. Vibration protocols were compared in repeated measurements using the ANOVA and post-hoc methods. Based on the test results, a vibration frequency range of 30 to 35 Hz positively affected the countermovement jump, while the 30 Hz frequency range positively affected squat jumps. Furthermore, frequency ranges of 25, 30, and 35 Hz positively affected the ROM. This effect was most intensely revealed in the 35 Hz frequency range. Applying vibrations between the ranges of 30-35 Hz on preadolescent karate practitioners is believed to acutely improve both jump and ROM performance.
Effect of dietary supplementation of giloy herb and ascorbic acid along with different bedding materials on fortnight feed consumption and feed conversion ratio of Japanese quail

The present experiment was conducted on four hundred thirty two (432) seven day-old Japanese quail chicks for a period of 24 weeks to investigates the effects of supplementation (giloy, ascorbic acid and combination of both) along with different bedding materials (sand, saw dust and wheat straw) on body weight and body weight gain of Japanese quails ( Coturnix coturnix japonica ). Birds were randomly and uniformly distributed in total 12 treatment groups comprising of 36 birds in each group and each group further divided into two replicates comprising 18 birds in each replicate. Highly significant ( P <0.01) effect of incorporation of supplements and different bedding material was found on feed consumption And Feed conversion ratio. The interaction effect of bedding material and supplementation was non-significant on feed consumption and significant for Feed conversion ratio. Minimum and best feed conversion ratio was observed in the group supplemented with combination of giloy and ascorbic acid along with sand bedding material. The highest Fortnight feed consumption of Japanese quail was found in sand bedding material group supplemented with combination. The present studies show that combination of dietary supplements giloy and vitamin C along with sand bedding material significantly improves feed consumption ratio.