Miracle-dz/UniFAR-FTUs huggingface dataset:
Networking and Women Academics’ Career Success in the Malaysian Research Universities

Women career success is an important focus in today's research works. Past research reveals limited attention on the relationships between networking behaviors and women academics’ career success. Thus, this study investigates the influence of networking behaviors on the objective and subjective career success of 146 women academics in two Malaysian research universities. The study utilized a descriptive correlational study design and used a questionnaire for the data collection. From the regression analysis, active involvement in networking behaviors was found to contribute significantly to women academics’ objective and subjective career success. This study enhances career success among women academics in the Malaysian research universities by highlighting the networking opportunities they have to achieve greater success in their careers. Therefore, these findings are useful to human resource development practitioners to include in their developmental programs and to encourage lifelong learning.
Water, sanitation and the COVID-19 in the Amazon

Several studies on the pathophysiological and epidemiological characteristics of SARS-CoV-2 indicate the extracorporeal viability of the virus and the possibility of faecal-oral transmission through contaminated natural water and wastewater, suggesting a potential risk of spreading in socially vulnerable areas, such as the Brazilian Amazon, where access to sanitation and health services is lacking. Thus, an attempt we made to outline an overview of sanitation in the Brazilian Amazon and its possible impacts on the most vulnerable populations and on the health system in a pandemic situation, based on bibliographic and documentary review and exploratory analysis of data related to basic sanitation and health. The Amazon has a huge deficit in sanitation and in the structure of health services, especially in rural areas, increasing the risk of spreading infectious diseases such as COVID-19, whose progress has placed some of the Amazonian states in a prominent position in the rankings of incidence and mortality. What do you want to do ? New mail Copy
Identi cation of Novel Survival Related lncRNA- miRNA-mRNA Competing Endogenous RNA Network Associated with Immune In ltration in Colorectal Cancer

Jianxin Li The A liated Hospital of Southwest Medical University https://orcid.org/0000-0001-9863-6493 Ting Han The A liated Hospital of Southwest Medical University Xin Wang The A liated Hospital of Southwest Medical University Yinchun Wang The A liated Hospital of Southwest Medical University Qingqiang Yang (  yangqingqiang121@163.com ) The A liated Hospital of Southwest Medical University https://orcid.org/0000-0001-7304-3501
Antigen Storage Compartments in Mature Dendritic Cells Facilitate Prolonged CTL Cross- Priming Capacity

Dendritic cells (DCs) are crucial for priming of naïve CD8+ T lymphocytes to exogenous antigens, so called cross-priming. We report that exogenous protein antigen can be conserved for several days in mature DCs, coinciding with strong CTL cross-priming potency in vivo. After MHC class I peptide elution, protein antigen-derived peptide presentation is efficiently restored, indicating the presence of an intracellular antigen depot. We characterized this depot as a lysosome-like organelle, distinct from MHC class II compartments and recently described early endosomal compartments that allow acute antigen presentation in MHC class I. The storage compartments we report here facilitate continuous supply of MHC class I ligands. This mechanism ensures sustained cross-presentation by DCs, despite the short-lived expression of MHC class I/peptide complexes at the cell surface. Supplementary Figure 2 (A) Induction of OVA-specific CTL in WT recipient mice (n=4) that were not injected (naïve), or injected i.v. with BM DC derived from B6 WT mice (black bars) or bm1 mice (white bars) pulse-loaded for one hour with IgG-OVA and subsequently cultured for 48 hours in the absence of antigen, measured by tetramer analysis. Error bar represents standard error of the mean (SEM). (B) Induction of OVA-specific CTL in WT recipient mice (n=5) that were not injected (naïve), or injected i.v. with BM DC derived from WT mice (black bars), transporter associated with antigen processing (TAP) deficient mice (white bars, TAP KO) or TAP/β2M deficient mice (white bars, TAP/ β2M KO), pulseloaded for one hour with IgG-OVA and subsequently cultured for 48 hours in the absence of antigen, measured by tetramer analysis. Error bar represents SEM. Equal uptake of IgG-OVA and upregulation of co-stimulatory molecules CD40 and CD86 by all BM DCs after 48 hrs culture was verified by flow cytometry (data not shown). In both models, T cell induction was largely abrogated by BM DCs that were not capable of MHC class I presentation of the antigenic peptide. These experiments indicate that injected DCs directly induce antigen-specific CD8+ T cells while antigen transfer to other APC plays a negligible role in the CTL cross-priming we have observed. Antigen depot facilitates sustained cross-presentation by DC | 97
Heterogeneity in Manufacturing Growth Risk

We analyze differences in output growth risk with respect to financial conditions across U.S. manufacturing industries. Using a multi-level quantile regression approach, we find strong heterogeneity in growth risk, particularly between the more vulnerable durable goods sector and the more resilient nondurable goods sector. Moreover, we show that industry characteristics significantly explain these differences. Large, or material intensive durable goods producing, or energy intensive nondurable goods producing industries are more vulnerable to adverse financial conditions, while industries engaging in labor hoarding, or with a high capital or overhead labor intensity are less susceptible.
Measuring well-being in emerging adults: Exploring the PERMA framework for positive youth development

Η θeωρία PERMA συγκeντρώνeι στοιχeία από το μοντέλο PERMA, τις δυνάμeις του χαρακτήρα και το eυ ζην. Αυτή η μeλέτη τοποθeτeίται στο πλαίσιο της θeτικής eκπαίδeυσης και έχeι στόχο να eξeτάσeι eμπeιρικά αυτήν την πολυδιάστατη θeωρία μe αναδυόμeνους eνηλίκους που φοιτούν στην ανώτατη eκπαίδeυση. 516 φοιτήτριeς και φοιτητές eλληνικών Πανeπιστημίων ηλικίας 18 έως 29 eτών κλήθηκαν να συμμeτάσχουν σe μία διαδικτυακή διeρeύνηση (α) των πέντe στοιχeίων του PERMA, δηλαδή των θeτικών συναισθημάτων, της eμπλοκής, των σχέσeων, του νοήματος ζωής και της eπίτeυξης, (β) τeσσάρων στοιχeίων του χαρακτήρα, δηλαδή της πeριέργeιας, της eυγνωμοσύνης, της αγάπης για τη μάθηση και του χιούμορ, καθώς και (γ) τριών δeικτών του eυ ζην, δηλαδή της ακμαιότητας, της ανθeκτικότητας και της θeτικής αντίληψης. Η διαμόρφωση των συσχeτισμών eντός και μeταξύ των τριών διαστάσeων της θeωρίας οδήγησe στην κατανόηση τόσο της πολυδιάστατης φύσης του eυ ζην, όσο και συγκeκριμένων σχέσeων ανάμeσα στις τρeις αυτές διαστάσeις. Τέλος, συζητούνται οι eπιπτώσeις των αποτeλeσμάτων της έρeυνας σe θeωρητικό και eφαρμοσμένο eπίπeδο σe ό,τι αφορά στην προώθηση της θeτικής ανάπτυξης των νέων στην ανώτατη eκπαίδeυση.
Can the Superior’s Choice of an Information System Diminish its Behavioral Benefit? A Further Examination of Information System Effects on Budgetary Reporting Honesty

Researchers have documented a behavioral benefit of an information system in that reducing information asymmetry regarding the level of honesty in the budget increases reporting honesty (Hannan, Rankin, & Towry, 2006; Abdel-Rahim & Stevens, 2018). We extend this literature by examining whether the superior’s choice to implement an information system diminishes this behavioral benefit. Consistent with prior results, we observe an increase in reporting honesty when the information system is randomly assigned. When the information system is chosen by the superior, however, we find that this behavioral benefit is significantly reduced. This reduction is attributable to the behavior of subordinates who score high in social norm sensitivity as measured by the Responsibility scale of the JPI-R (Jackson 1994). Exit questionnaire responses reveal that while both high and low norm sensitivity subordinates viewed the superior’s choice of an information system as a signal of distrust, only high norm sensitivity subordinates felt less obligated to report honestly as a result. A path analysis provides further evidence that the superior’s implementation choice reduced reporting honesty in high norm sensitivity subordinates by reducing their obligation for reporting honestly in the budget. This study documents a crowding-out effect for information systems and provides evidence regarding the underlying factors behind that effect.
The Influence of Concomitant Administration of Simvastatin at Different Doses with Metoprolol on Heart Rate and Blood Pressure in Normo- cholesterolemic and Hypercholesterolemic Rats*

Background. β1-adrenergic blocking drugs and inhibitors of HMGCo-A reductase (statins) are widely used by a lot of patients in the prevention of cardiovascular events. Previous studies have shown that the administration of statins influences β adrenergic signaling. Objectives. The aim of the study was to evaluate the influence of a chronic 4-week administration of simvastatin given at different doses with concomitant metoprolol on heart rate and blood pressure. Material and Methods. The experiments were performed in normotensive Wistar rats. The animals were divided into 2 groups: normocholesterolemic and hypercholesterolemic. During the 4 weeks, hypercholesterolemic rats received a diet with 5% cholesterol and 2,5% cholic acid. Drugs: metoprolol 30 mg × kg–1 b.w. ; simvastatin 1 mg × × kg–1 b.w. ; simvastatin 20 mg × kg–1 b.w. ; simvastatin 1 mg × kg–1 b.w. + metoprolol 30 mg × kg–1 b.w. , or simvastatin 20 mg × kg–1 b.w. + metoprolol 30 mg kg–1 b.w. were given intragastrically over the 4-week period. For the evaluation of heart rate and blood pressure, the signals were provided by an Isotec pressure transducer. Results. Concomitant administration of simvastatin at 1 and 20 mg × kg–1 b.w with metoprolol in normocholesterolemic rats statistically decreased heart rate as compared to the control group and the group receiving simvastatin alone. No statistical differences between the groups receiving simvastatin at dose 1 mg/kg–1 with metoprolol and simvastatin at dose 20 mg/kg–1 with metoprolol (381.64 ± 7.90 vs. 388.21 ± 5,15 1/min p = 0.05) were observed. In the hypercholesterolemic animals, the heart rate evaluation after concomitant administration of simvastatin given at different doses with metoprolol showed comparable statistical implications as compared to normocholesterolemic rats. Concomitant administration of simvastatin in different doses on normoand hypercholesterolemic rats did not significantly influence blood pressure. Conclusions. No significant impact of chronic administration of simvastatin given at different doses to normoand hypercholesterolemic Wistar rats receiving metoprolol on the heart rate was observed (Adv Clin Exp Med 2011, 20, 1, 39–45).
Evaluation of the role of sex as a prognostic factor in critically ill adults with sepsis: a systematic review and meta-analysis

Background: Incidence and sepsis-related mortality are failing, but sepsis continues to be a leading cause of admission and death in intensive care units (ICUs). Although the preceding evidence suggests sex-related risk differences for developing sepsis, the influence of sex on mortality outcomes remains unclear as previous studies showed discordant results. This systematic review assesed the independent effect of sex for mortality among critically ill patients with sepsis.Methods: Electronic databases were searched up to 17th July 2020 for studies that examined independent associations between sex and mortality outcomes in critically ill adults with sepsis while controlling for covariates. Primary meta-analyses were performed by pooling adjusted estimates for a pre-specified core set of adjustment factors. The primary outcomes included all-cause hospital mortality and 28-day all-cause hospital mortality. The secondary outcomes included 7-day all-cause hospital mortality, 1-year all-cause mortality, and all-cause ICU mortality.Results: Among the 14304 records identified, 12 studies (71850 participants) were included. Meta-analysis showed inconclusive results on sex-based differences in hospital mortality (OR 0.95, 95% CI 0.55 to 1.64; very low-certainty evidence) and ICU mortality (OR 1.19, 95% CI 0.79 to 1.78; very low-certainty evidence). Meta-analysis found higher 28-day hospital mortality in the female group (OR 1.18, 95% CI 1.05 to 1.32; very low-certainty evidence). No studies reported on 7-day hospital mortality. A single study provided adjusted estimates on 1-year mortality reporting lower risk in the female group (OR 0.83 95% CI 0.68 to 0.98; low-certainty of evidence). The main reasons for assessing the certainty of evidence as very low were inconsistency and imprecision while downgrading to low-certainty was risk of bias and imprecision.Conclusions: The prognostic independent effect of sex on hospital mortality, 28-day hospital mortality, and ICU mortality for critically ill adults with sepsis is uncertain. Female sex may be associated with decreased 1-year mortality. No included studies reported on 7-day all-cause hospital mortality.
From RNA World to SARS-CoV-2: The Edited Story of RNA Viral Evolution

The current SARS-CoV-2 pandemic underscores the importance of understanding the evolution of RNA genomes. While RNA is subject to the formation of similar lesions as DNA, the evolutionary and physiological impacts RNA lesions have on viral genomes are yet to be characterized. Lesions that may drive the evolution of RNA genomes can induce breaks that are repaired by recombination or can cause base substitution mutagenesis, also known as base editing. Over the past decade or so, base editing mutagenesis of DNA genomes has been subject to many studies, revealing that exposure of ssDNA is subject to hypermutation that is involved in the etiology of cancer. However, base editing of RNA genomes has not been studied to the same extent. Recently hypermutation of single-stranded RNA viral genomes have also been documented though its role in evolution and population dynamics. Here, we will summarize the current knowledge of key mechanisms and causes of RNA genome instability covering areas from the RNA world theory to the SARS-CoV-2 pandemic of today. We will also highlight the key questions that remain as it pertains to RNA genome instability, mutations accumulation, and experimental strategies for addressing these questions.
Farnesoid X Receptor Agonist Treatment Alters Bile Acid Metabolism butExacerbates Liver Damage in a Piglet Model of Short-BowelSyndrome

Intestinal Failure and Clinical Nutrition Group, Murdoch Childrens Research Institute, Parkville, Victoria, Australia; APC Microbiome Institute, School of Microbiology, School of Pharmacy, School of Biochemistry, University College Cork, Cork, Ireland; Department of Veterinary and Agricultural Sciences, Department of Paediatrics, University of Melbourne, Parkville, Australia; Hudson Institute of Medical Research, Clayton, Victoria, Australia; Department of Gastroenterology and Clinical Nutrition, Royal Children’s Hospital, Parkville, Victoria, Australia
The effect of boundary layer thickness on cavity flow over a backward-facing step

Ventilated cavities detaching from a backward facing step are investigated for a range of upstream boundary layer thicknesses in a cavitation tunnel. The upstream turbulent boundary layer thickness is varied by artificial thickening of the test section natural boundary layer using an array of transversely injected jets. Momentum thickness Reynolds numbers from 8.5 to 28×103 were tested giving boundary layer thickness to step height ratios from 1.25 to 3.8. A range of cavitation numbers (based on the cavity pressure) were obtained by variation of the ventilation flow rate for fixed freestream Reynolds and cavitation numbers. Cavity length to step height ratios from 15 to 60 were achieved. Cavity length was found to be linearly dependent on ventilation rate and to decrease with increasing boundary layer thickness. This result may have implications in the practical optimization of these flows which occur in applications such as drag reduction on marine hull forms.
THERMAL ANLYSIS AND LIPID OXIDATIVE STABILITY OF SERBIAN TRADITITIONAL DRY FERMENTED SAUSAGE FROM SREM COUNTY

Thermal characteristics of tradititional dry fermented sausage from Srem County was studied by Differential Scanning Calorimetry (DSC). The aim of the study was to obtain the thermal characteristics and lipid oxidative stability of Serbian tradititional dry fermented sausage from Srem County and considering results obtained could gave information about the quality and durability of sausage. The DSC thermogram of the sausage’s meat assayed in this work, showed the characteristic endothermal transition in the low temperature range from -35 °C to -10 °C correspondning to water melting and in the temperature range from 90 °C to 120 °C correspondning to water evaporation. The DSC thermogram of the fat from sausage has three endothermal transitions, specific for pork lard. Oxidation stability of fat from the sausage was checked by DSC-OOT method and the kinetic parameters of the lipid oxidation (Ea energy of activation, Z preexponential factor and k oxidation rate constant) were obtained by the Kissinger-Akahira-Sunose (KAS) method. From DSC results obtained the free and bound water were determined, and information about lipid oxidation of sausage’s fat suggested good overall stability and quality of meat product.
Effect of nitrogen and phosphorus levels on yield and quality of summer pearlmillet

A field experiment was carried out during summer season 2019 to find out the effect of nitrogen and phosphorus levels on yield and quality of summer pearlmillet at Agronomy Instructional Farm, Chimanbhai Patel College of Agriculture, Sardarkrushinagar Dantiwada Agricultural University, Sardarkrushinagar. Total nine treatments of different levels of nitrogen and phosphorus were tested randomized complet block design with factorial concept. Among different levels, an application of 160 kg N/ha and 90 kg P2O5/ha recorded significantly higher number of effective tiller per plant, length of earhead, test weight and grain and straw yield compared to other treatment.
Genetic variability studies in bottle gourd ( Lagenaria siceraria L . )

The present investigation was carried out to estimate phenotypic and genotypic coefficient of variation, heritability (broad sense) and genetic advance per cent of mean for 14quantitative traits in 21 different genotypes of bottle gourd during Kharif 2018 at Instructional-Cum-Research Farm, Department of Horticulture, College of Agriculture Latur, Vasantrao Nike Marathwada Krishi Vidyapeeth (M.S.). Significant differences among the genotypes were observed for all the characters under study. The PCV and GCV values were high for vine length, number of branches per plant, sex ratio, fruit length, fruit diameter, fruit yield per plot, fruit yield per hectare, fruit yield per vine,. High heritability and high genetic advance were observed for characters like vine length, number of branches per plant, node at which first female flower appear, days required first female appear, number of male flower, sex ratio, fruit length, fruit diameter, fruit weight, fruit yield per vine, fruit yield per plot and fruit yield per hectare.
Tariff policies , variable markups , and within-sector misallocation ∗

This study examines the influence of import tariff policies on welfare in a twocountry model with heterogeneous firms and variable markups. In this model, the market outcome under free trade provides too small (large) output level for more (less) productive firms and too many varieties due to markup pricing, which can be partially compensated by import tariffs. If countries cooperatively adopt a symmetric import tariff, the efficient tariff that maximizes the total welfare level of the two countries is positive when the introduction of the small symmetric import tariff sufficiently improves this within-sector misallocation.
Wasp-waisted behavior in magnetic hysteresis curves of CoFe2O4 nanopowder at a low temperature: experimental evidence and theoretical approach

We theoretically and experimentally investigated wasp-waisted magnetic hysteresis curves at a low temperature for CoFe2O4 nanopowders. Our theoretical approach proposes a physical mechanism that leads to wasp-waisted behavior for a single magnetic phase with the same anisotropic field, contrary to that of typical multi-phase magnetic systems. Our simulations show that a combination of effects, namely easy-plane anisotropy configuration and dipolar interactions, results in a double peak in the magnetic susceptibility curve of a granular magnetic system. As experimental evidence of such an effect, we present a CoFe2O4 nanopowder and its structural and magnetic characterizations, which support a single magnetic phase. In addition, the evidence does not corroborate many explanations reported in the literature for wasp-waisted magnetic behavior. Our results provide evidence for a tetragonal crystalline phase of CoFe2O4 due to magneto-elastic coupling, recently reported in the literature.
A novel opinion about the coupling loss between single- mode fibers and waveguides

A detailed analysis is presented, about the coupling loss dependence on the waveguide mode eccentricity and symmetry between single-mode fibers and waveguides. A new conclusion is obtained that more symmetric waveguide mode leads to lower coupling loss, but less eccentric waveguide mode does not always mean low coupling loss, which depends on the waveguide mode depth.
Kinetics and mechanisms of hydrogen isotope exchange over solid storage media

Hydrogen isotope separation systems using palladium (Pd) are currently being designed for both reactor designs with the aim of separating and purifying the reactor exhaust products which contain valuable unspent hydrogen isotopes. Hydrogen isotope exchange in Pd offers an efficient, ambient condition process that can produce pure isotopic species in a process far simpler and less costly than the current state of the art cryogenic distillation processes. The method is applicable whether separating hydrogen (protium), deuterium or tritium and any combination of these. If practical fusion devices are ever to be realised it is essential to produce an economical and efficient fuel cycle capable of separating and purifying hydrogen isotopes. Hydrogen isotope exchange in Pd is also of interest to the waste separation and purification industries, in particular those using hydrogen separation membranes which used Pd and Pd-alloy membranes. Understanding hydrogen isotope exchange, with particular regard to the formation of the intermediate (and often unwanted) hydrogen deuteride (HD), will aid significantly in future designs of hydrogen isotope separation systems. Novel hydrogen isotope exchange experiments involving hydrogen and deuterium at a number of temperatures (208 K, 293 K and 373 K) and pressures (1.3 bar – 8 bar) not yet explored are presented in this thesis. The experiments were carried out on a unique piece of laboratory apparatus provided to and further developed at the University of Bath. Alongside experimentation, a novel comprehensive multidimensional multi-physics model has been created to analyse the experimental data obtained using the new apparatus and elucidate the kinetics and mechanisms of the reactions occurring between hydrogen isotopic species and Pd during hydrogen isotope exchange based on Langmuir-Hinshelwood surface reaction mechanism. The surface reaction rates, kinetic rate constants and heat effects have been examined in detail, and in tandem, for the first time.