Miracle-dz/UniFAR-FTUs huggingface dataset:
Multi-Spacecraft Observations of Interplanetary Shocks: Non-Planarity and Energetic Particles

Numerical simulations of the evolution of interplanetary shocks exhibit growth of distortions of the shock front and nonuniformity of energetic particles from place to place near the shock surface. In this work we use multispacecraft (ACE, Wind, IMP 8, Geotail, Interball-Tail, SOHO, and Genesis) observations near Earth to search for such effects. On scales of 10 5 to 10 6 km, most of the 26 shocks studied were inconsistent with planar structures or with spherical structures with a radius of 1 AU. The average local radius of curvature was ∼3 x 10 6 km. There were also differences in the intensities and time profiles of energetic particle fluxes seen at both ACE and Wind.
Lipoprotein a Combined with Fibrinogen as an Independent Predictor of Long-Term Prognosis in Patients with Acute Coronary Syndrome: A Multi-Center Retrospective Study

Background: Patients with acute coronary syndrome (ACS) still have a high risk of recurrence of major adverse cardiovascular and cerebrovascular events (MACCE). However, there are rare studies on the prediction of MACCE in patients with ACS using lipoprotein a [Lp(a)] combined with fibrinogen. The aim of this study was to analyze the predictive value of Lp(a) combined with fibrinogen for the long-term prognosis of patients with ACS. Methods: 804 patients with ACS admitted to 11 tertiary general hospitals in Chengdu from January 2017 to June 2019 were included in the study. According to the Lp(a) 300 mg/L, patients were assigned to the non-high Lp(a) group and high Lp(a) group. Patients were assigned to the non-high or high fibrinogen groups using the fibrinogen level of 3.08 g/L. Subsequently, patients were divided into group A, B, or C by Lp(a) combined with fibrinogen. The study endpoints were MACCE, including all-cause death, non-fatal myocardial infarction, non-fatal stroke, and revascularization. The incidences of MACCE among groups were compared. Lp(a), fibrinogen, Lp(a) combined with fibrinogen classifications were each added into the basic model to construct three new models. The C-index, net reclassification index (NRI) and integrated discrimination improvement (IDI) of the three new models were then compared. Results: The median follow-up was 16 months. During follow-up, the cumulative incidence of MACCE in group C was significantly higher than that measured in group A and B (p < 0.001). The results of the multivariate Cox regression analysis of MACCE showed that Lp(a) ≥300 mg/L with fibrinogen ≥3.08 g/L was an independent predictor of MACCE. According to the GRACE score and the statistical analyses, the basic model was constructed, which had a C-index of 0.694. The C-index, NRI, and IDI of the new model constructed using the basic model + Lp(a) combined with fibrinogen classification were 0.736, 0.095, and 0.094 respectively. Conclusions: Single Lp(a), single fibrinogen and Lp(a) combined with fibrinogen were independent predictors of MACCE in patients with ACS. The predictive value of Lp(a) combined with fibrinogen in patients with ACS was better than that of single Lp(a) and single fibrinogen.
Emotion Analysis of Occluded Facial Expressions - A Review of Literature

Emotions are really crucial in our daily lives. ; hence the understanding and detection of emotional reactions are essential for human research. Emotions are multifaceted phenomena that influence our behavior, perception, and cognition. Once trained, both humans and machines can discern emotions in images. As a result, prior researchers have investigated various machine learning algorithms for emotion analysis utilizing image processing. We did a comprehensive literature evaluation to determine the present state of research and research gaps in the above topic. We looked into various essential factors, such as types of emotions and partially occluded facial expressions. Occlusions arise when someone is wearing glasses (e.g., in a virtual reality application) or a face mask, (e.g., in medical context). Current issues in overcoming partial occlusion as well as potential technological advancements were examined. The study contributes significantly by providing a detailed and up-to-date assessment of past initiatives in the chosen domain.
The effect of many minor mergers on the size growth of compact quiescent galaxies

Massive galaxies with a half-mass radius 2), but not in the local universe. In the local universe similar-mass (within a factor of two) galaxies tend to be a factor of 4 to 5 larger. Dry minor mergers are known to drive the evolution of the size of a galaxy without much increasing the mass, but it is unclear if the growth in size is sufficient to explain the observations. We test the hypothesis that galaxies grow through dry minor mergers by simulating merging galaxies with mass ratios of q=1:1 (equal mass) to q=1:160. In our N-body simulations the total mass of the parent galaxy doubles. We confirm that major mergers do not cause a sufficient growth in size. The observation can be explained with mergers with a mass ratio of q=1:5--1:10. Smaller mass ratios cause a more dramatic growth in size, up to a factor of ~17 for mergers with a mass ratio of 1:80. For relatively massive minor mergers q ~> 1:20 the mass of the incoming child galaxies tend to settle in the halo of the parent galaxy. This is caused by the tidal stripping of the child galaxies by the time they enter the central portion of the parent. When the accretion of minor galaxies becomes more continuous, when q <~ 1:40, the foreign mass tends to concentrate more in the central region of the parent galaxy. We speculate that this is caused by dynamic interactions between the child galaxies inside the merger remnant and the longer merging times when the difference in mass is larger. These interactions cause dynamical heating which results in accretion of mass inside the galaxy core and a reduction of the parent's circular velocity and density.
The Potential Applications of Commercial Arbuscular Mycorrhizal Fungal Inoculants and Their Ecological Consequences

Arbuscular mycorrhizal fungal (AMF) inoculants are sustainable biological materials that can provide several benefits to plants, especially in disturbed agroecosystems and in the context of phytomanagement interventions. However, it is difficult to predict the effectiveness of AMF inoculants and their impacts on indigenous AMF communities under field conditions. In this review, we examined the literature on the possible outcomes following the introduction of AMF-based inoculants in the field, including their establishment in soil and plant roots, persistence, and effects on the indigenous AMF community. Most studies indicate that introduced AMF can persist in the target field from a few months to several years but with declining abundance (60%) or complete exclusion (30%). Further analysis shows that AMF inoculation exerts both positive and negative impacts on native AMF species, including suppression (33%), stimulation (38%), exclusion (19%), and neutral impacts (10% of examined cases). The factors influencing the ecological fates of AMF inoculants, such as the inherent properties of the inoculum, dosage and frequency of inoculation, and soil physical and biological factors, are further discussed. While it is important to monitor the success and downstream impacts of commercial inoculants in the field, the sampling method and the molecular tools employed to resolve and quantify AMF taxa need to be improved and standardized to eliminate bias towards certain AMF strains and reduce discrepancies among studies. Lastly, inoculant producers must focus on selecting strains with a higher chance of success in the field, and having little or negligible downstream impacts.
O i fluorescent line contamination in soft X-ray diffuse background obtained with Suzaku/XIS

The quantitative measurement of OVII line intensity is a powerful method for understanding the soft X-ray diffuse background. By systematically analyzing the OVII line intensity in 145 high-latitude Suzaku/XIS observations, the flux of OI fluorescent line in the XIS spectrum, contaminating the OVII line, is found to have an increasing trend with time especially after 2011. For these observations, the OVII line intensity would be overestimated unless taking into consideration the OI fluorescent line contamination. Since the OI line emission originates from solar X-rays, this increase suggests that incident solar X-rays at the OI fluorescence energy tend to be larger than the early phase of Suzaku observations (2005 - 2010).
The Job Creation Law and REDD+: Possible synergies and challenges

• The Job Creation Law is intended to improve economic development through deregulating investment procedures and supporting entrepreneurialism in a typical market-oriented business model. The stronger legal basis for social forestry and multi-business forestry permit are intended to promote forest and environmental sustainability. • As an overarching law, it mandates the alignment of other sectoral regulations. Synchronization between economic sectors is needed to ensure the sustainability of forest functions in supporting emission reduction. • Both Job Creation Law and REDD+ promote entrepreneurialism, but efforts to generate rural ‘green’ jobs should also focus on aspects pertaining to rural labour markets, migration, and whether the appropriation of only forestuse rights (with highly technical requirements) would really benefit emission reductions and the livelihoods of marginalized rural communities. • Before UUCK amendment is ready and ratified, it is important for the government to determine WPK area for results-based payments (a government-led program) and carbon trading purposes (which can be assigned to private sector). • Further research is needed to understand to what extend Job Creation Law would affect the integrity of REDD+ designated areas (WPK), and how the law and REDD+ can together promote the creation of rural ‘green’ jobs and foster emission reduction from forestry sector. DOI: 10.17528/cifor/008651 | cifor-icraf.org No. 371, August 2022
CONSTRAINTS ON THE VISCOSITY AND MAGNETIC FIELD IN HOT ACCRETION FLOWS AROUND BLACK HOLES

The magnitude of the viscosity and magnetic field parameters in hot accretion flows is investigated in low luminosity active galactic nuclei (LLAGNs). Theoretical studies show that a geometrically thin, optically thick disk is truncated at mass accretion rates less than a critical value by mass evaporated vertically from the disk to the corona, with the truncated region replaced by an advection dominated accretion flow (ADAF). The critical accretion rate for such a truncation is a function of the viscosity and magnetic field. Observations of X-ray photon indices and spectral fits of a number of LLAGNs published in the literature provide an estimate of the critical rate of mass accretion and the truncation radius, respectively. By comparing the observational results with theoretical predictions, the viscosity and magnetic field parameters in the hot accretion flow region are estimated. Specifically, the mass accretion rates inferred in different sources constrain the viscosity parameter, whereas the truncation radii of the disk, as inferred from spectral fits, further constrain the magnetic field parameter. It is found that the value of the viscosity parameter in the corona/ADAF ranges from 0.17 to 0.5, with values clustered about 0.2–0.3. Magnetic pressure is required by the relatively small truncation radii for some LLAGNs and is found to be as high as its equipartition value with the gas pressure. The inferred values of the viscosity parameter are in agreement with those obtained from the observations of non-stationary accretion in stellar mass black hole X-ray transients. This consistency provides support for the paradigm that a geometrically thin disk is truncated by means of a mass evaporation process from the disk to the corona at low mass accretion rates.
Depressive Symptoms and Ageism among Nursing Home Residents: The Role of Social Support

(1) Background: Ageism refers to the stereotyping, prejudice, and discrimination against older individuals or groups based on their age. This study investigates the modifying role of social support in the relationship between depressive symptoms and ageism in China; (2) Methods: A cross-sectional study was performed in 21 nursing homes in Jinan from March to June in 2019. The data were analyzed through a multilevel mixed-effects generalized linear model; (3) The analysis showed that older adults in nursing homes experienced moderate levels of ageism. There were significant interaction effects between depressive symptoms and social support on overall ageism and objective ageism after controlling for covariates (p < 0.05). As the level of social support increased, the predicted ageism greatly reduced among older adults without depressive symptoms when compared to those with depressive symptoms; (4) Conclusions: This study highlights the importance of identifying strategies to enhance social support and reduce depressive symptoms for nursing home residents. Having positive attitudes toward aging and overcoming negative age-related stereotypes may benefit older adults’ physical and mental health, well-being, and help to promote an age-friendly society.
The Effects of Seven-Day Exposure to Silver Nanoparticles on Fertility and Homeostasis of Zebrafish (Danio rerio)

Silver nanoparticles (AgNPs) are found in open waters, but the effect of their low concentrations on an organism’s homeostasis is not fully understood. The aim of the study was to determine the short-term exposure effects of AgNPs coated by PvP (polyvinylpyrrolidone) on the homeostasis of livers and gonads in zebrafish. Sexually mature zebrafish were exposed for seven days to silver ions (0.01 mg/dm3) or AgNPs (0.01; 0.05; 0.1; 0.5; 1.0 mg/dm3). On the last day, the liver, testes, and ovaries were subjected to a histology analysis. In the liver, we analyzed the expression of the cat, gpx1a, gsr, sod1, and cyp1a genes. On the last day of the experiment, the lowest survival rate was found in the AgNPs 0.05 mg/dm3 group. The histological analysis showed that AgNPs and silver ions cause an increase in the area of hepatocytes. The highest proliferation index of hepatocytes was found in the AgNP 0.05 mg/dm3 group. Furthermore, AgNPs were found to interfere with spermatogenesis and oogonesis as well as reduce the expression levels of the cat, gpx1a, and sod1 genes in the liver compared with the control group. Based on the results, it can be concluded that exposure to AgNPs causes cytotoxic changes in zebrafish, activates the immune system, negatively affects the process of meiosis in the gonads, and generates oxidative stress.
On abduction and answer generation through constrained resolution

Recently, extensions of constrained logic programming and constrained resolution for theorem proving have been introduced, that consider constraints, which are interpreted under an open world assumption. We discuss relationships between applications of these approaches for query answering in knowledge base systems on the one hand and abduction-based hypothetical reasoning on the other hand. We show both that constrained resolution can be used as an operationalization of (some limited form of) abduction and that abduction is the logical status of an answer generation process through constrained resolution, ie. , it is an abductive but not a deductive form of reasoning.
Nonaxisymmetric Poynting jets

The relativistic plasma jets from a misaligned black hole-accretion disk system will not be axially symmetric. Here we analyze nonaxisymmetric, stationary, translation invariant jets in the force-free approximation where the field energy dominates the particle energy. We derive a stream equation for these configurations involving the flux function $\psi$ for the transverse magnetic field, the linear velocity $v(\psi)$ of field lines along the jet, and the longitudinal magnetic field $B_z(\psi)$. The equations can be completely solved when $|v|=1$, and when $|v| E^2$. Finally, we write down specific solutions approximating numerical results for the nonaxisymmetric jet produced by a spinning black hole in an external, misaligned magnetic field.
Emotional State of Young Men in Relation to Problematic Internet Use

The Internet has become an indispensable tool in communication, business, entertainment, and obtaining information. Behavioral addictions are disorders associated with uncontrolled activity feeding the reward system, motivation, and memory. The purpose of this study was to assess the emotional state in terms of problematic Internet use. The survey was conducted in 2020–2021 in the West Pomeranian region of Poland and involved 500 men aged 18–30 (24.82 ± 3.83). The study was conducted using our own original questionnaire regarding the amount of time spent playing computer games during the weekdays and on days off; the type of school/university; financial situation; as well as the manner, purpose, and degree of Internet use. Other questionnaires were also used, i.e., Beck Depression Inventory, Internet Use Test, GAD-7 Generalized Anxiety Assessment Questionnaire, and Buss and Perry Aggression Questionnaire. Problematic use of the Internet may result in the occurrence of anxiety, anger, hostility or depression. Longer duration of Internet activity was correlated to higher scores on the Internet Use Test degree of problematic Internet use. There was a correlation between the severity of mild depression symptoms and the occurrence of anxiety, verbal and physical aggression, and problematic Internet use.
Red Light Enhances Plant Adaptation to Spaceflight and Mars g-Levels

Abstract Understanding how plants respond and adapt to extraterrestrial conditions is essential for space exploration initiatives. Deleterious effects of the space environment on plant development have been reported, such as the unbalance of cell growth and proliferation in the root meristem, or gene expression reprogramming. However, plants are capable of surviving and completing the seed-to-seed life cycle under microgravity. A key research challenge is to identify environmental cues, such as light, which could compensate the negative effects of microgravity. Understanding the crosstalk between light and gravity sensing in space was the major objective of the NASA-ESA Seedling Growth series of spaceflight experiments (2013–2018). Different g-levels were used, with special attention to micro-g, Mars-g, and Earth-g. In spaceflight seedlings illuminated for 4 days with a white light photoperiod and then photostimulated with red light for 2 days, transcriptomic studies showed, first, that red light partially reverted the gene reprogramming induced by microgravity, and that the combination of microgravity and photoactivation was not recognized by seedlings as stressful. Two mutant lines of the nucleolar protein nucleolin exhibited differential requirements in response to red light photoactivation. This observation opens the way to directed-mutagenesis strategies in crop design to be used in space colonization. Further transcriptomic studies at different g-levels showed elevated plastid and mitochondrial genome expression in microgravity, associated with disturbed nucleus–organelle communication, and the upregulation of genes encoding auxin and cytokinin hormonal pathways. At the Mars g-level, genes of hormone pathways related to stress response were activated, together with some transcription factors specifically related to acclimation, suggesting that seedlings grown in partial-g are able to acclimate by modulating genome expression in routes related to space-environment-associated stress.
Italian Precision Medicine in Pediatric Oncology: Moving beyond Actionable Alterations

Neuroblastoma (NB) is the most common extracranial solid tumor encountered in childhood. Although there has been significant improvement in the outcomes of patients with high-risk disease, the prognosis for patients with metastatic relapse or refractory disease is poor. Hence, the clinical integration of genome sequencing into standard clinical practice is necessary in order to develop personalized therapy for children with relapsed or refractory disease. The PeRsonalizEdMEdicine (PREME) project focuses on the design of innovative therapeutic strategies for patients suffering from relapsed NB. We performed whole exome sequencing (WES) of patient-matched tumor-normal samples to identify genetic variants amenable to precision medicine. Specifically, two patients were studied (First case: a three-year-old male with early relapsed NB; Second case: a 20-year-old male who relapsed 10 years after the first diagnosis of NB). Results were reviewed by a multi-disciplinary molecular tumor board (MTB) and clinical reports were issued to the ordering physician. WES revealed the mutation c.G320C in the CUL4A gene in case 1 and the mutation c.A484G in the PSMC2 gene in case 2. Both patients were treated according to these actionable alterations, with promising results. The effective treatment of NB is one of the main challenges in pediatric oncology. In the era of precision medicine, the need to design new therapeutic strategies for NB is fundamental. Our results demonstrate the feasibility of incorporating clinical WES into pediatric oncology practice.
ABCB1 Is Frequently Methylated in Higher-Grade Gliomas and May Serve as a Diagnostic Biomarker of More Aggressive Tumors

ABCB1 belongs to a superfamily of membrane transporters that use ATP hydrolysis to efflux various endogenous compounds and drugs outside the cell. Cancer cells upregulate ABCB1 expression as an adaptive response to evade chemotherapy-mediated cell death. On the other hand, several reports highlight the role of the epigenetic regulation of ABCB1 expression. In fact, the promoter methylation of ABCB1 was found to be methylated in several tumor types, including gliomas, but its role as a biomarker is not fully established yet. Thus, the aim of this study was to analyze the methylation of the ABCB1 promoter in tumor tissues from 50 glioma patients to verify its incidence and to semi-quantitively detect ABCB1 methylation levels in order to establish its utility as a potential biomarker. The results of this study show a high interindividual variability in the ABCB1 methylation level of the samples derived from gliomas of different grades. Additionally, a positive correlation between ABCB1 methylation, the WHO tumor grade, and an IDH1 wild-type status has been observed. Thus, ABCB1 methylation can be regarded as a potential diagnostic or prognostic biomarker for glioma patients, indicating more aggressive tumors.
Kadanoff-Baym equations with non-Gaussian initial conditions: The equilibrium limit

The nonequilibrium dynamics of quantum fields is an initial-value problem, which can be described by Kadanoff-Baym equations. Typically, and, in particular, when numerical solutions are demanded, these Kadanoff-Baym equations are restricted to Gaussian initial states. However, physical initial states are non-Gaussian correlated initial states. In particular, renormalizability requires the initial state to feature n-point correlations that asymptotically agree with the vacuum correlations at short distances. In order to identify physical nonequilibrium initial states, it is therefore a precondition to describe the vacuum correlations of the interacting theory within the nonequilibrium framework. In this paper, Kadanoff-Baym equations for non-Gaussian correlated initial states describing vacuum and thermal equilibrium are derived from the 2PI effective action. A diagrammatic method for the explicit construction of vacuum and thermal initial correlations from the 2PI effective action is provided. We present numerical solutions of Kadanoff-Baym equations for a real scalar {phi}{sup 4} quantum field theory, which take the thermal initial four-point correlation as the leading non-Gaussian correction into account. We find that this minimal non-Gaussian initial condition yields an approximation to the complete equilibrium initial state that is quantitatively and qualitatively significantly improved as compared to Gaussian initial states.