Miracle-dz/UniFAR-FTUs huggingface dataset:
Local and Regional Therapies for Hepatocellular Carcinoma

Local and regional therapies are recommended for patients with hepatocellular carcinoma (HCC) in very early (BCLC 0), early (BCLC A), and intermediate stages (BCLC B. However, in clinical practice the decision to select one of the available approaches has to take into account several parameters that go far beyond the general recommendations exposed in clinical practice guidelines. Adequate selection of candidates for each option with proven survival benefit is key to secure an optimal outcome in terms of survival, while avoiding major morbidity and securing the best quality of life. This assessment to recommend treatment requires the effective collaboration of a multidisciplinary tumor board so that a personalized approach is in place. This review provides a comprehensive up-to-date overview of available techniques, explaining the advantages and disadvantages of the different loco-regional treatments. It aims to provide guidance for evidence based treatment decisions, while also pointing out the current limitations and future prospects that need to be confirmed by ongoing research.
Structural changes in coniferous stands along a chronosequence and a productivity gradient in the northeastern boreal forest of Québec

ABSTRACT The influence of stand age and site conditions on the structure of coniferous stands was studied in the boreal forest of Québec's Côte-Nord, a region with low fire recurrence. Stand diameter diversity was measured in 2202 forest inventory plots in black spruce (Picea mariana), balsam fir (Abies balsamea), and mixed stands using the Shannon-Wiener diversity index. A relative productivity index was developed based on the relationship between height and age of dominant trees. A stepwise regression analysis indicated that this productivity index best explains stand structure variation in all composition types, while stand age seems to influence structure more at the beginning of stand development. The results suggest that productive stands become uneven-sized earlier than unproductive stands and also maintain a greater diameter diversity. These contrasting structural dynamics may be explained by (i) a higher growth rate in richer stands that likely induces earlier senescence and thus an earlier passage to an uneven-sized structure and (ii) a restricted maximum tree diameter in poor stands caused by a scarcity of resources, which in turn reduces the diameter diversity of these stands, even after their break-up time.
Significance of Trianthema portulacastrum L. in sustenance of Apis florea colonies during dearth period.

The paper reports flowering phenology, floral visitors of Trianthema portulacastrum and melissopalynological analyses of 8 honey samples and 374 pollen loads of Apis florea, collected during May to August from Bankura district, West Bengal. T. portulacastrum flowers during April to October. Flowers open at 6.30-7.00 am in the morning. Anther dehiscence takes place after 30 minutes from flower opening. Closing of the flower takes place at about 11.30 am – 12.15 pm. During the opening phase of the flower, a number of visitors viz. Apis cerana, A. florea, Augochloropsis metallica, Halictus sp. , Pseudoborbo bevani and Trigona iridipennis visit the flower for nectar or pollen. Melissopalynological analyses revealed that all the honey samples were multifloral in origin and T. portulacastrum present in all the honey samples. Regarding the pollen foraging scenario of the bee species, T. portulacastrum also played an important role during those months. The overall result reflects the importance of T. portulacastrum as a major source of both nectar and pollen grains for A. florea colonies during dearth period.
Explaining Speech Recognition and Quality of Life Outcomes in Adult Cochlear Implant Users: Complementary Contributions of Demographic, Sensory, and Cognitive Factors.

HYPOTHESES Adult cochlear implant (CI) outcomes depend on demographic, sensory, and cognitive factors. However, these factors have not been examined together comprehensively for relations to different outcome types, such as speech recognition versus quality of life (QOL). Three hypotheses were tested: 1) speech recognition will be explained most strongly by sensory factors, whereas QOL will be explained more strongly by cognitive factors. 2) Different speech recognition outcome domains (sentences versus words) and different QOL domains (physical versus social versus psychological functioning) will be explained differentially by demographic, sensory, and cognitive factors. 3) Including cognitive factors as predictors will provide more power to explain outcomes than demographic and sensory predictors alone. BACKGROUND A better understanding of the contributors to CI outcomes is needed to prognosticate outcomes before surgery, explain outcomes after surgery, and tailor rehabilitation efforts. METHODS Forty-one adult postlingual experienced CI users were assessed for sentence and word recognition, as well as hearing-related QOL, along with a broad collection of predictors. Partial least squares regression was used to identify factors that were most predictive of outcome measures. RESULTS Supporting our hypotheses, speech recognition abilities were most strongly dependent on sensory skills, while QOL outcomes required a combination of cognitive, sensory, and demographic predictors. The inclusion of cognitive measures increased the ability to explain outcomes, mainly for QOL. CONCLUSIONS Explaining variability in adult CI outcomes requires a broad assessment approach. Identifying the most important predictors depends on the particular outcome domain and even the particular measure of interest.
Screening for surface-active agent producing bacteria in used engine oil contaminated soil samples.

Biosurfactant producing bacteria were isolated from engine oil contaminated soils from auto mechanic workshops in Pudukkottai, Tamilnadu, South India. Haemolytic activity, emulsification activity, drop collapsing test as well as oil displacement test were used to determine biosurfactant producing activity of isolated bacterial strains. Among 25 different strains,5 strains exhibited clear zone on blood agar plates. Five strains named PDKT1-PDKT5 were identified by 16S rRNA Sequencing as a Serratia marcescens (99%homology); a Pseudomonas aerugenosa (99%homology);a Pseudomonas sp (98% homology);a Bacillus subtilus (99 %homology) and a Bacillus licheniformis (99% homology) strain, respectively. Strain PDKT-2 showed the highest activity for oil displacement test and emulsification test. In the present study an attempt on the significant role of bacteria in the production of biosufactant was made.
POSITION OF PRADANA IN NYEBURIN MARRIAGE REVIEWED FROM THE LAW OF BALI INDIGENOUS HERITAGE IN BANJAR KUTUH DESA SAYAN KECAMATAN UBUD KABUPATEN GIANYAR

The aims of this study are to know the Nyeburin Marriage Inheritance System in Banjar Kutuh, Sayan Village, Ubud District, Gianyar Regency women as Purusa or nyentana men as Pradana if their inheritance is in the form of land assets and to know the position of social social status of men as Pradana in Nyeburin Marriage in indigenous communities in the Village of Sayan Banjar Kutuh, Ubud District, Gianyar Regency. This method uses Empirical legal research. Using the statutory approach, case approach, and conceptual approach. Sources of data are sourced from primary data (field research) and secondary data (library research). Data collection techniques consisted of interview techniques, document study techniques, and literature study techniques. The data collected was analyzed descriptive qualitatively. The author uses the theory of justice, the theory of legal certainty, the theory of reception in complex u. Based on the results of the study it was found that the inheritance of nyeburin marriage in Banjar village is still strong in women because of their status as Purusa and their social social status is different if the work of a person who becomes a pradana, for example, a doctor may look higher. The conclusion is that a woman still has the right to inherit because as a purusa and if the inheritance in the form of land remains the right of the woman and in social status remains the head of the household in the community remains the same except for work that makes their social status different.
Structural Characterization of Oat Bran (1→3), (1→4)-β-D-Glucans by Lichenase Hydrolysis Through High-Performance Anion Exchange Chromatography with Pulsed Amperometric Detection

Cereal mixed linkages (1 → 3) (1 → 4)-β-D-glucan is a linear polysaccharide composed of glucose units. Oat β-glucan is a natural polymer. The main products of β-glucanase are oligosaccharides with DP3 and DP4, i.e., 3-Ob-cellobiosyl-D-glucose and 3-Ob-cellotriosyl-D-glucose, which represent over 90% of the molecule. Keeping in mind all the benefits of oat bran, the present study was planned to investigate the structural properties of oat bran, high-performance anion exchange chromatography with pulsed amperometric detection was used to examine these oligosaccharides. The structural analysis of oat bran of two oat varieties revealed that the ratio of soluble and insoluble triose to tetraose in β-glucan fraction was 1.44 and 1.78, respectively, for Avon variety; while the ratio of soluble and insoluble triose to tetraose in β-glucan fraction for Sargodha-81 was 1.49 and 1.77. The major units determined were cellotriose and cellotetraose. Other units cellopentaose and hexaoses were also existed but in minor fractions. Lichenase hydrolysis high-performance anion exchange chromatography with pulsed amperometric detection appeared to be the best choice for structural analysis of purified samples of mixed-linkage β-glucan.
Intracellular dynamics of Arabidopsis EDS1 immune regulatory complexes

Plants are resistant to most microbial pathogens due to the presence of an effective and multi-layered defense system. Arabidopsis ENHANCED DISEASE SUSCEPTIBILITY 1 (EDS1) and its interacting partners PHYTOALEXIN DEFICIENT 4 (PAD4) and SENESCENCE ASSOCIATED GENE 101 (SAG101) constitute an important regulatory node in disease resistance. Together they are essential for basal defense against invasive biotrophic and hemi-biotrophic pathogens, programmed cell death conditioned by TIR-type NB-LRR immune receptors and accumulation of the phenolic hormone salicylic acid (SA). It was previously shown that the central component EDS1 forms molecularly and spatially distinct complexes with PAD4 and SAG101 in the cytoplasm and the nucleus of healthy plants. The fate of these complexes during defense responses and the relevance of their distribution were not known. The work presented here shows that no major redistribution of EDS1 occurs at late stages of infection or in immune-deregulated backgrounds since its steady-state levels increase in both the nuclear and cytoplasmic compartments. By contrast, enrichment in nuclear EDS1 was observed during early stages of TIR-NB-LRR mediated responses, suggesting that the nuclear pool of EDS1 has a role in rapid signal relay to this compartment after specific pathogen recognition. Treatment of Arabidopsis protoplasts expressing EDS1-YFP with nuclear export inhibitors revealed that EDS1 is able to shuttle between the nucleus and the cytoplasm, further suggesting a role for EDS1 in relaying important information between both compartments. To gather information about the functional significance of EDS1 distribution and discriminate cytosolic from nuclear functions, I examined whether manipulation of EDS1 localization affects its functionality. Transgenic plants were generated in which a nuclear export signal (NES), the hormone binding domain of the rat glucocorticoid receptor (GR) or a nuclear localization signal (NLS) were attached to a functional EDS1-YFP fusion and expressed in an eds1 null mutant background. EDS1 nuclear exclusion through the presence of the NES or cytosolic tethering by the GR led to reduced basal, TIR-NB-LRR-mediated and systemic resistance. Conversely, allowing nuclear accumulation of EDS1-YFP-GR fusion protein through dexamethasone treatment enhanced resistance. Results also pointed to a role of cytosolic EDS1 in modulating plant cell death that may relate to the balance of reactive oxygen species and SA. Strikingly, constitutive driving of EDS1 to the nucleus by addition of an NLS results in a dose-dependent developmental reprogramming that likely reflects the need for rigorous control of nuclear EDS1 levels. In sum, these studies point to a key nuclear activity of EDS1 complexes in regulating plant immune responses that may link immune receptor activation to gene expression outputs.
Effects of Early Defoliation on Yield, Fruit Composition, and Harvest Season Cluster Rot Complex of

Viticulture in Michigan is limited by a cool and humid climate and as a result, there is a problem of harvest season cluster rot, especially in cultivars with compact cluster morphology. Economically important wine grape varieties in eastern North America possess varying susceptibility to harvest season cluster rot. Some important cultivars that are susceptible are Pinot gris, Pinot noir, Riesling (Vitis vinifera L.) as well as Seyval and Vignoles (French-American hybrids or interspecific hybrid cultivars). A common characteristic of these cultivars is the compactness of the berries held on the cluster rachis. The aim of this work was to determine whether a quantified amount of leaf removal or a temporary reduction in carbon assimilation at the beginning of bloom would reduce fruit set and cluster compactness. Vines subjected to removal of four or six basal leaves had an average fruit set reduction of '45% from a non-treated control. Cluster weight and berries per cluster were similarly reduced with a greater effect on the basal than the apical cluster of the shoot. Reduced fruit set was associated with a reduction in cluster compactness and harvest season rot. This was also reflected in yield and basic fruit chemistry parameters associated with the importance of basal leaves to the developing cluster. Multiple applications of stylet oil at different time intervals resulted in significant reduction in net photosynthesis (Pn). A single application had no significant impact on Pn, whereas multiple applications reduced leaf assimilation rates. However, this reduction in Pn did not reduce fruit set or improve cluster compactness. There was a strong negative effect of early leaf removal in Year 1 on vine performance in Year 2; this carryover effect increased shootless nodes per vine, reduced the number of clusters per shoot and per vine, and dramatically reduced fruit set and consequently yield per vine.
Effect of Accelerated ageing on Seed Viability and Biochemical Components of the Edible Bamboo Dendrocalamus brandisii (Munro) Kurz

Dendrocalamus brandisii is a very large evergreen bamboo, which is commonly used for house building, for making baskets, handicrafts and furniture. Young shoots of D. brandisii are edible. Although, abundant seed production is observed during gregarious flowering, viability of seeds under natural conditions is very short. In the present study, accelerated ageing test was carried out to predict the storability of seeds. Seeds were subjected to accelerated ageing at 42±1°C with a relative humidity of 100% for 0, 1, 3, 5 and 8 days, in a covered water bath. Germination test and biochemical analyses were carried out for control and aged seeds. The initial germination percentage was 59.71% and after accelerated ageing germination declined to 15.39%. Total soluble proteins, sugars and starch content decreased during the ageing process. There was a gradual decrease in the activity of acid and alkaline phosphatase and peroxidase, while the activity of �-amylase and �-amylase increased during accelerated ageing. Hence the decrease in the viability of D. brandisii seeds may be due to the changes in the biochemical content and the activity of enzymes involved in the degradation of seed reserves.
Can organisational work–life policies improve work–life interaction? A scoping review

Abstract Objective Understanding the role of organisational policies in improving work–life interaction is important, as such policies may provide a legitimate means to extend working life, potentially leading to improved retention in a number of sectors. This review aimed to critique contemporary literature on the relationship between employee work–family conflict or work–life balance and availability or usage of organisational policies developed to assist employees to manage their work–life interaction better. Method Academic literature published between 2000 and March 2018 was systematically searched using CINAHL, EMBASE, PsycINFO, and MEDLINE. Results Sixteen studies met the inclusion criteria. Results were mixed for studies addressing organisational policy uptake: some showed uptake improved work–life interaction but others showed no or even negative effects. Some studies revealed gender effects. Policy availability alone, however, does not appear to be related to improved work–life interaction. Conclusions Findings highlight the importance of ensuring organisational policies developed are nuanced and embedded within a supportive work–family culture that enables employees to utilise the policies to alter their work arrangements and the work–life interaction experienced.
Antimicrobial effects of commercial herbs, spices and essential oils in minced pork

Effect of fresh and dried garlic, onion, thyme and oregano on the bacterial germ count of minced pork stored at 5°C was evaluated. All spices were added in 1% concentration. Furthermore, MIC (Minimal Inhibitory Concentration) values of marjoram and thyme essential oils on Escherichia coli were determined in vitro, and their antibacterial effect was tested in minced pork inoculated with E. coli. In general, fresh spices showed weak or no inhibition on the total cell count of minced pork, or even caused increased microbe count. On the contrary, dried garlic and thyme decreased total cell count with 1 or two orders of magnitude. MIC values for marjoram and thyme essential oils were 0.5 µl/ml and 2 µl/ml, respectively. The essential oils decreased E. coli cell number in minced pork with 1 log cfu after 24 h storage at 5°C.
A Fully FPGA Implementation of SVPWM for Three-phase Inverters without External Reference Signals

In this paper we propose a novel method to implement Space Vector Pulse Width Modulation algorithm in Field Programmable Gate Array hardware. It is based on storing pre-calculated and normalized dwell times in internal Look-Up Tables of FPGA and on the evaluation through FPGA of the effective dwell times, as function of the modulation index, and of the relative configurations of the power transistors. The input data is the modulation index, instead the switching frequency and the output frequency are defined when the normalized dwell times are calculated. This method permits to significantly reduce hardware resources and computational cost of the FPGA. Although it is proposed to drive three-phase motor in open-loop control, the modulation index can be linearly changed from the user in real-time so that a start-up ramp of the output voltage amplitude ca be performed, for example. The method is implemented on FPGA Artix7 from Xilinx, Inc. by using 420 LUT and 245 FF, which are, respectively, 2.2% and 0.59% of the overall resources, without requiring any Digital Signal Processing and BRAMs. Experimental results show the gate control signals of the power transistors to generate an output voltage at 50Hz with a start-up voltage ramp and a switching frequency of 9.75kHz.
Using Ultraviolet-A radiation and antifungals for treatment of dermatophytes isolated from cattle and farm workers

Dermatophytes are classified into 3 genera of fungi that commonly involve keratins tissue types; skin, nails and hairs in mammals. Ultraviolet radiation are used in the treatment of these fungi which cause DNA damage leading to inactivation of the pathogenic fungus. The present study was aimed to evaluate the ultraviolet (UV) radiation influence on the dermatophytes lesion growth that attack human and animal. Thirty isolates of dermatophytes were isolated from animals (skin scraping) and humans (skin scraping, hair and nail). Five species were identified viz., Trichophyton mentagrophyte, Trichophyton interdigitale, Trichophyton tonsurans, Trichophyton violaceum and Microsporum canis. UV-A, was found to be more active in delaying the dermatophytes colony growth in some current fungi widespread when combined with antifungal therapy to treat skin superficial fungal diseases, which caused dermatophytes lesion in human and animal. The present approach that a combination of antifungal drugs and UV-A to treat apparent dermatophytes diseases could reduce the therapeutic period and dosages which improve patients compliance.
Transglobal leadership approach to sustainable tourism competitiveness at tourism sector-engaged MSMEs through integrated human resource performance and responsible marketing

This study aims to examine the effect of transglobal leadership on quality of work life (QWL), job involvement, organizational citizenship behavior (OCB) and human resource (HR) performance of tourism sector-engaged micro, small and medium enterprises (MSMEs) in East Java; to examine the moderating role of QWL, job involvement and OCB in the effect of transglobal leadership on HR performance of tourism sector-engaged MSMEs in East Java; to examine the effect of HR performance of tourism sector-engaged MSMEs on responsible tourism marketing and sustainable tourism competitiveness in East Java; and to examine the mediating role of responsible tourism marketing in the effect of HR performance of tourism sector-engaged MSMEs on sustainable tourism competitiveness in East Java. ,The population of this research was all HR executives of tourism sector-engaged MSMEs in East Java and domestic and foreign tourists in East Java. The sampling of the tourism sector-engaged MSMEs in East Java (in 16 tourism potential cities) was performed using a purposive sampling technique. Determination of the sample size was made using the minimum criterion from structural model, ranging from 100 to 200. Thus, it was determined that the number of tourism sector-engaged MSMEs studied in this research was 200 enterprises from 16 tourism potential cities in East Java. From each tourism sector MSME, four employees and three tourists were selected. In total, this research involved 800 employees and 600 tourists (both domestic and foreign). ,This research found that transglobal leadership (X) , QBL (M1), job involvement (M2) and OCB (M3) had an effect on HR performance (Y). The results of this research highlighted that QWL variable (M1) moderated the effect of transglobal leadership (X) on HR performance (Y). It was found that job involvement variable (M2) moderated the effect of transglobal leadership (X) on HR performance (Y). This research also detected that OCB variable (M3) moderated the effect of transglobal leadership (X) on HR performance (Y). This research found that HR performance (Y) had an effect on responsible marketing (Z1). It was obtained in this research that HR performance (Y) also had an effect on sustainable tourism competitiveness (Z2). Finally, this research found that responsible marketing (Z1) had an effect on sustainable tourism competitiveness (Z2). ,Regarding the originality of this research, the holistic compilation was integrated from the theoretical concept of the HR and marketing strategies through the implementation of the tourism marketing concept and application that are responsible for tourism sector-engaged MSMEs in East Java. Of course, tourists need to get a good understanding of the marketing strategy to participate in controlling the sustainable tourism competitiveness in East Java.