Miracle-dz/UniFAR-FTUs huggingface dataset:
A Biomedical Case Study Showing That Tuning Random Forests Can Fundamentally Change the Interpretation of Supervised Data Structure Exploration Aimed at Knowledge Discovery

Knowledge discovery in biomedical data using supervised methods assumes that the data contain structure relevant to the class structure if a classifier can be trained to assign a case to the correct class better than by guessing. In this setting, acceptance or rejection of a scientific hypothesis may depend critically on the ability to classify cases better than randomly, without high classification performance being the primary goal. Random forests are often chosen for knowledge-discovery tasks because they are considered a powerful classifier that does not require sophisticated data transformation or hyperparameter tuning and can be regarded as a reference classifier for tabular numerical data. Here, we report a case where the failure of random forests using the default hyperparameter settings in the standard implementations of R and Python would have led to the rejection of the hypothesis that the data contained structure relevant to the class structure. After tuning the hyperparameters, classification performance increased from 56% to 65% balanced accuracy in R, and from 55% to 67% balanced accuracy in Python. More importantly, the 95% confidence intervals in the tuned versions were to the right of the value of 50% that characterizes guessing-level classification. Thus, tuning provided the desired evidence that the data structure supported the class structure of the data set. In this case, the tuning made more than a quantitative difference in the form of slightly better classification accuracy, but significantly changed the interpretation of the data set. This is especially true when classification performance is low and a small improvement increases the balanced accuracy to over 50% when guessing.
The role of corporate governance in increasing risk reporting: A comparative study of emerging markets companies

The purpose of this study is to explore the level of presentation of risk information reports called risk reporting (RR) in the annual reports of Indonesian and Malaysian non-financial companies. In addition, this study aims to empirically examine the role of corporate governance (CG) in presenting RR and compare its role in the two countries. The method used in this study is content analysis with 113 samples of Indonesian companies and 70 Malaysian companies. The results showed that the board of directors (BD) of Indonesian companies represented by the board of commissioners and independent commissioners and the boards of Malaysian companies represented by the board of directors and independent directors had the same role, in line with the research of Yubiharto and Rudianti (2021), and Yermack (1996). However, in Indonesia, it plays a role in increasing the number of RRs, while in Malaysia, it is the opposite. The results of this research are also preliminary evidence that there is a difference in the role of the CG structure, which is a two-tier and one-tier system.
Awareness of Diabetic Retinopathy Among Diabetic Patients in King Khalid Eye Specialist Hospital, Riyadh, Saudi Arabia

Introduction: Diabetic retinopathy (DR) is a leading cause of blindness. Over a third of the population with diabetes (DM) develop DR. Therefore, we aimed to investigate the awareness level of DR in the subjects with DM attending clinics at King Khaled Eye Specialist Hospital (KKESH) in Riyadh, Saudi Arabia. Methods: A cross-sectional study was carried out in KKESH. Responses from 360 subjects (men and women) with DM were collected using a validated questionnaire after obtaining informed consent. The questionnaire was constructed to assess the level of knowledge about DR, its screening, prevention, and treatment. The questionnaire responses were utilized thereafter to assess the association between the level of awareness of DR and the characteristics of the subjects. Pearson's chi-squared test was computed to exhibit the association and a p-value of <0.05 was considered significant. Results: Almost all the subjects answered six or more questions, thereby considered aware of DR. Only 3.6% of the subjects knew how often their eyes should be screened for DR. Only 3.2% of the subjects with DM type 1 (DM1) knew when their eyes should be examined after being diagnosed with DM. Men exhibited a significantly higher (p= 0.04) level of awareness compared to women. Comparing the other characteristics of the subjects exhibited no significant differences. In conclusion, although the studied population exhibited a good level of awareness about DR, they would benefit from further education on DR, especially on how regularly their vision is recommended to be examined to prevent DR and its consequences.
Geospatial epidemiology of hypertension and its risk factors in India: Findings from National Family Health Survey (2015–2016)

Background: The fourth round of National Family Health Survey (2015–2016) measured blood pressure for the first time and provided a unique opportunity of exploring trends in hypertension prevalence across states and districts for the first time. Aim: This study will be the first in India to estimate the geospatial variation of hypertension among those in the 15–49 years age group in India. Materials and Methods: Out of a total of 616,346 selected occupied households, 601,509 were successfully interviewed, giving a response rate of 98%. We adjusted the proportion of hypertension obtained by using national sample weights. We built a multivariable logistic regression model to assess the determinants of hypertension. Results: The overall weighted prevalence of hypertension was 11.7%, and the prevalence was 11.1% in females and 11.0% in males. Urban areas had a higher prevalence (13.0%) compared to rural areas (11.0%). Those with no education (14.4%) and those who reported smoking (16.5%) had hypertension. Consumption of alcohol, fruits, and eggs was also found to be significantly related to hypertension. Conclusion: Hypertension epidemic is spreading alarmingly in India across rural and urban populations. Disturbingly, the hypertension prevalence is now becoming more concentrated among the poor. This phenomenon has serious implications for the country's social and economic well-being. Urgent preventive measures need to be taken at a multidisciplinary level.
Did Human Microbes Affect Tourist Arrivals before the COVID-19 Shock? Pre-Effect Forecasting Model for Slovenia

In 2020, with a substantial decline in tourist arrivals slightly before the time of COVID-19, the innovative econometric approach predicted possible responses between the spread of human microbes (bacteria/viruses) and tourist arrivals. The article developed a conceptually tested econometric model for predicting an exogenous shock on tourist arrivals driven by the spread of disease using a time series approach. The reworked study is based on an autoregressive integrated moving average (ARIMA) model to avoid spurious results. The periods of robust empirical study were obtained from the data vectors i) from January 2008 to December 2018 and ii) from January 2008 to December 2020. The data were obtained from the National Institute of Public Health (NIPH) and the Statistical Office of the Republic of Slovenia. The ARIMA model predicted the number of declines in tourist arrivals for the approaching periods due to the spread of viruses. Before the outbreak of COVID-19, pre-pandemic results confirmed a one-fifth drop in tourist arrivals in the medium term. In the short term, the decline could be more than three-quarters. A further shock can be caused by forecasted bacterial infections; less likely to reduce tourist demand in the long term. The results can improve the evidence for public health demand in risk reduction for tourists as possible patients. The data from the NIPH are crucial for monitoring public health and tourism management as a base for predictions of unknown events.
Characteristic Factors Influencing the Thai-Style Public Space Utilization: Case Study of Sanam Na Mueang Public Park in Nakhon Si Thammarat Old Town, Thailand

This research aims to identify the characteristic factors influencing the Thai-style public space utilization with the combination of variables of good public space characteristics following the occidental and Thai theories from the perspective of actual users in order to create new components or factors influencing the Thai-style public space utilization. Sanam Na Mueang Public Park, located in Nakhon Si Thammarat Old Town, was specified as the study area. Principal component analysis (PCA) was employed to classify 30 variables influencing the success of public space utilization; data was collected from questionnaire responses provided by 320 people. The results indicate that the new characteristic factors influencing Thai-style public space utilization consist of contextual connection and space identity, landscape elements, and aesthetics of public space utilization. These results reflect that both contextual connection and space identity, and landscape elements are consistent with occidental theories that prioritize physical characteristics and promote the access and facilitation, while the aesthetics of public space utilization, in contrast to occidental theories, prioritize the aesthetics of utilization and visibility to the surrounding people and activities.
Two-Dimensional InSAR Monitoring of the Co- and Post-Seismic Ground Deformation of the 2021 Mw 5.9 Arkalochori (Greece) Earthquake and Its Impact on the Deformations of the Heraklion City Wall Relic

Contributing to the United Nations 2030 Sustainable Development Goals (SDGs) within Target 11.4 “Strengthen efforts to protect and safeguard the world’s cultural and natural heritage”, it is critical to monitor the spatial and temporal stabilities of cultural heritages. The study of the interactive relationship between earthquakes and the protection of cultural heritages needs to be strengthened. On 27 September 2021, the destructive Mw 5.9 Arkalochori earthquake occurred ~25 km away from the city of Heraklion (Greece) where the Heraklion City Wall (HCW), a representative cultural heritage of Greece and Europe, was located. This offered a proper case to investigate the shortcomings aforementioned. Here, we intend to set up and answer the following three questions (Whether, Where and What, 3Ws): Whether there were impacts on the HCW caused by the Arkalochori earthquake? Where did the maximum deformation occur? What was the relationship between seismic deformation between the epicenter and the HCW over time? We performed two-dimensional (2D) InSAR measurements for both co-seismic and post-seismic deformations using the ascending and descending Sentinel-1A SAR images. The spatial-temporal characteristics of Up–Down (UD) and East–West (EW) were revealed. The 2D co-seismic deformation field showed that the near-filed deformations were dominating compared with the deformations at the HCW, the UD deformation was mainly featured with subsidence with a maximum value of ~21 cm, the EW deformation was ~9 cm westward and ~10 cm eastward. The time-series measurements showed that: (1) temporally, the HCW responded quickly to the Arkalochori earthquake, and the accumulative deformations at the seven different bastions of the HCW showed the same trend as the near-field area over time. (2) Spatially, the closer to the Mw 5.9 epicenter, the larger the deformations that occurred. (3) The EW and UD deformation trends of the HCW that were consistent with the Mw 5.9 epicenter were interrupted at the middle time spot (22 January 2022), indicating the influence of another earthquake sequence consisting of eight earthquakes with magnitudes larger than 3.5 that happened on 16–18 January 2022. Respectively, to summarize and address the aforementioned 3Ws based on the post-seismic analysis accomplished by the MSBAS method, the Arkalochori earthquake did affect the HCW; besides, the influences of the ~13 km earthquake sequence were also detected; the nearest part to the epicenter suffered the most; the deformation trends of the HCW were approximately the same with the epicenter area of the Arkalochori earthquake both in the UD and EW directions.
Mayo Clinic Clival Chordoma Case Series: Impact of Endoscopic Training on Clinical Care

Simple Summary Clival chordoma is a rare malignant tumor that commonly arises near the center of the brain. In 2013, multidisciplinary team was introduced in our facility to manage clival chordoma effectively. We analyzed its effect by comparing the outcomes of patients from “before 2013” (19 patients) and “after 2013” (39 patients). After 2013, the endoscopic endonasal approach was more commonly used (90%; “before 2013”, 32%) to achieve gross to near total resections (64%; “before 2013”, 16%) with less post-operative new cranial nerve deficits (3%; “before 2013”, 32%). Gross to near total resection was associated with less recurrence (hazard ratio, 0.31; 95% confidence interval, 0.11 to 0.91; p = 0.033). The multidisciplinary team led to improved tumor resection rate, less tumor recurrence rate, and less morbidity. Abstract The management of clival chordoma in our group shifted around 2013 to mostly endoscopic, and proton beam was introduced for our multidisciplinary team. Consecutive patients who had surgical resection from 1987 to 2021 were reviewed. A total of 58 patients (39 patients after 2013) were analyzed. The mean tumor size was 3.7 cm, and the most common location was the upper clivus (43%). Compared to before 2013, after 2013, the endoscopic endonasal approach was more common (90%, p < 0.001), and more gross or near total resections (64%, p = 0.002) were attained. Ten cases (17%) were revision surgeries referred from elsewhere, and three cases (5%) underwent additional surgery elsewhere before adjuvant radiation. The postoperative cerebrospinal fluid leak occurred in 7%. Post-operative new cranial nerve deficits occurred in 32% before 2013, compared to 2.6% after 2013 (p = 0.004). For cases before 2013, 10 patients (53%) recurred during the median follow-up of 144 months (mean, 142 months), whereas for cases after 2013, seven patients (18%) recurred with a median follow-up of 35 months (mean, 42 months). 5-year progression-free survival was 58%, and 5-year overall survival was 87%. A specialized multidisciplinary team improved the resection rate compared to a historical cohort with an excellent morbidity profile.
Atomic layer deposition of LaxZr1−xO2−δ (x=0.25) high-k dielectrics for advanced gate stacks

Thin LaxZr1−xO2−δ (x=0.25) high permittivity (k) films are grown on Si(100) by atomic layer deposition at 300 °C using (PirCp)3La, (MeCp)2ZrMe(OMe) and O3 species. Their properties are studied by grazing incidence x-ray diffraction, high resolution transmission electron microscopy, electron energy loss spectroscopy, x-ray photoelectron spectroscopy, and electrical measurements on the as-grown films and after vacuum annealing at 600 °C. Annealed films feature resistance to hygroscopicity, a large k value of around 30 and an acceptable leakage current density. A low-k silica-rich interlayer is also evidenced at both pristine and annealed high-k/Si interfaces.
Pengaruh Sistem Informasi Akuntansi Dan Standar Akuntansi Pemerintah Terhadap Kualitas Laporan Keuangan Daerah

This study aims to examine the Effect of Accounting Information Systems and Government Accounting Standards on the Quality of Financial Reports (empirical study on Sijunjung Regency). While the research sample is the Head, Treasurer, and Financial Staff in the OPD (Regional Apparatus Organization) Sijunjung Regency, amounting to 81 respondents. The type of data used is primary data. The sampling technique used is total sampling by distributing questionnaires.The results showed that the Accounting Information System (X1) had an effect on the Quality of Financial Statements (Y). This result is evidenced by the significance value of t of 0.000 < 0.05. while the Government Accounting Standards (X2) affect the Quality of Financial Statements (Y).
Factors Affecting the Life Satisfaction of Older People with Care Needs Who Live at Home

The number of older people is increasing rapidly, and the number of older people with care needs who live at home is also increasing in Japan. Maintaining their life satisfaction has been a primary challenge. This study aimed to identify factors affecting the life satisfaction of older people with care needs. The study was conducted among older people using homecare services; 126 participants (mean age, 79.33 ± 7.51 years, 54 male) were included in the analysis. Logistic regression analysis with adjustment for age, sex, and economic status was conducted with life satisfaction as the objective variable and the Japanese version of occupational gaps questionnaire (OGQ-J), sense of coherence, functional independence measure, and environmental factors as explanatory variables. The variables that significantly affected life satisfaction were the OGQ-J (p = 0.0352, OR 0.90, 95% CI 0.81–0.99) and environmental factors (p = 0.0083, OR 4.41, 95% CI 1.52–14.11). This study’s results indicate the importance of focusing on environmental factors and facilitating the participation of older people with care needs in activities they want to do to maintain and improve their life satisfaction.
Mechanistic Temperature-Size Rule Explanation Should Reconcile Physiological and Mortality Responses to Temperature

The temperature-size rule is one of the universal rules in ecology and states that ectotherms in warmer waters will grow faster as juveniles, mature at smaller sizes and younger ages, and reach smaller maximum body sizes. Many models have unsuccessfully attempted to reproduce temperature-size rule-consistent life histories by using two-term (anabolism and catabolism) Pütter-type growth models, such as the von Bertalanffy. Here, we present a physiologically structured individual growth model, which incorporates an energy budget and optimizes energy allocation to growth, reproduction, and reserves. Growth, maturation, and reproductive output emerge as a result of life-history optimization to specific physiological rates and mortality conditions. To assess which processes can lead to temperature-size rule-type life histories, we simulate 42 scenarios that differ in temperature and body size dependencies of intake, metabolism, and mortality rates. Results show that the temperature-size rule can emerge in two ways. The first way requires both intake and metabolism to increase with temperature, but the temperature-body size interaction of the two rates must lead to relatively faster intake increase in small individuals and relatively larger metabolism increase in large ones. The second way requires only higher temperature-driven natural mortality and faster intake rates in early life (no change in metabolic rates is needed). This selects for faster life histories with earlier maturation and increased reproductive output. Our model provides a novel mechanistic and evolutionary framework for identifying the conditions necessary for the temperature-size rule. It shows that the temperature-size rule is likely to reflect both physiological changes and life-history optimization and that use of von Bertalanffy-type models, which do not include reproduction processes, can hinder our ability to understand and predict ectotherm responses to climate change.
Diversification of the Pristimantis conspicillatus group (Anura: Craugastoridae) within distinct neotropical areas throughout the Neogene

Determining the relative importance of dispersal and vicariance events across neotropical regions is a major goal in biogeography. These events are thought to be related to important landscape changes, notably the transition of Amazonia toward its modern hydrological configuration ca. 10 million years ago. We investigated the spatio-temporal context of the diversification of one of the major lineages of Pristimantis, a widespread and large genus of direct-developing Neotropical frogs. We gathered a spatially and taxonomically extensive sampling of mitochondrial DNA sequences from 754 Pristimantis gr. conspicillatus specimens, which led to delimiting 75 Operational Taxonomic Units (OTUs). Complete mitogenomes of 35 of these OTUs were assembled and collated with two nuDNA loci to reconstruct a time-calibrated phylogeny. We identified five major clades that diverged around the Oligocene-Miocene transition and that are largely restricted to distinct Neotropical regions i.e. Western Amazonia (P. conspicillatus clade), the Brazilian Shield (P. fenestratus clade), the Atlantic Forest (P. ramagii clade), the Guiana Shield (P. vilarsi clade) and the northern Andes (P. nicefori clade). The majority of the diversification events within these clades occurred in-situ from the early Miocene onward. Yet, a few ancient dispersal/vicariance events are inferred to have occurred among trans-Andean forests, the Atlantic Forest, the Brazilian and the Guiana Shields, but almost none in the last 10 Ma. The radical landscape transformations during the Miocene caused by the Andean orogeny and hydrological barriers such as the Pebas System and the subsequent transcontinental configuration of the Amazon drainage is a likely explanation for the isolation of the different clades within the P. gr. conspicillatus.
Is the Association between Age and Fertility Problems Modified by Diet Quality? Findings from a National Study of Reproductive Age Women in Australia

Background: Increasing age is a strong risk factor for infertility, and there is accumulating evidence of the importance of a healthier diet for fertility. Whether a healthier diet modifies the association between increasing age and infertility has not been investigated. This study aimed to (i) examine if better diet quality could help reduce age-related infertility; and (ii) assess whether changes in diet quality over time are associated with fertility problems. Methods: Data were from Surveys 3 and 5 of the 1973–1978 birth cohort of the Australian Longitudinal Study on Women’s Health. Cross-sectional analysis with multivariable generalized linear models were used to examine the association between age and fertility status, adjusted for various confounders. Multiplicative and additive effect modification by diet quality was assessed, with additive effect modification evaluated with the relative risk for interaction (RERI). Results: In total, 3387 women were included from Survey 3 (age range 24–31 years) and 5614 women from Survey 5 (age range 30–38 years); 588 (17.4%) and 1321 (23.4%) self-reported to have fertility problems in the respective surveys. In Survey 3, compared to younger women with a good-quality diet, older women with a poor-quality diet had a 43% increased risk for fertility problems, with risk increasing after further adjustment for BMI (RR: 1.59; 95% CI: 1.07, 2.37) and PCOS (RR: 1.74; 95% CI: 1.15, 2.62). In Survey 5 in younger women (<33.9 years), there was no association between diet quality and risk for infertility problems. The RERI (across different adjusted models) was between −0.08 (−0.70, 0.55) to −0.39 (−1.40, 0.62) in survey 3 and 0.07 (−0.17, 0.31) to 0.08 (−0.17, 0.32) in Survey 5. Conclusions: There is little evidence to suggest effect modification on the effect of age and fertility problems with diet quality.