Miracle-dz/UniFAR-FTUs huggingface dataset:
Ultrasound-assisted synthesis of eight novel and highly functionalized 2-aminonitrile oxazoles via Ugi-3CR

Eight novel 2-aminonitrile oxazoles were synthesized efficiently and quickly via the Ugi reaction in its three-component version in moderate to good yields (55-82%) at room temperature or in good to excellent yields (70-96%) using ultrasound irradiation (USI) as heat source. It is noteworthy that not only the yields were improved by using USI, also the reaction times decreased considerably, from 6-10 hours (at r.t.) to 1-2 hours (USI), depending on the substituents. The final products are highly functionalized molecules because they contain an amino group, a nitrile group, an oxazole group and a very reactive biaryl-benzylic position. In this context, they can be used for further condensations, cyclizations and/or functionalizations toward a variety of compounds with potential applications in several fields of knowledge like optics, material science and medicinal chemistry. All products were fully characterized by spectroscopic techniques (H and C-NMR, IR and HRMS), even by mp and Rf.
Reply to reviewer 2-second review

The 2013/14 winter averaged sea surface temperature (SST) was anomalously cool in the mid-North Atlantic region. This season was also unusually stormy with extratropical cyclones passing over the mid-North Atlantic every 3 days. However, the processes by which cyclones contribute towards seasonal SST anomalies are not fully quantified. In this paper a cyclone identification and tracking method is combined with ECMWF atmosphere and ocean reanalysis fields to calculate cyclone-relative net surface heat flux anomalies and resulting SST changes. Anomalously large negative heat flux is located 5 behind the cyclones cold front resulting in anomalous cooling up to 0.2K/day when the cyclones are at maximum intensity. This extratropical cyclone induced ’cold wake’ extends along the cyclones cold front but is small compared to climatological variability in the SST’s. To investigate the potential cumulative effect of the passage of multiple cyclone induced SST cooling in the same location we calculate Earth-relative net surface heat flux anomalies and resulting SST changes for the 2013/2014 winter period. Anomalously large winter averaged negative heat flux occurs in a zonally orientated band extending across the 10 North Atlantic between 40-60◦N. The 2013/2014 winter SST cooling anomaly associated with air-sea interactions (anomalous heat flux, mixed layer depth and entrainment at the base of the ocean mixed layer) is estimated to be -0.67 K in the mid-North Atlantic (68% of the total cooling anomaly). The role of cyclones is estimated using a cyclone masking technique which encompasses each cyclone centre and its cold wake. The environmental flow anomaly in 2013/2014 sets the overall tripole pattern of heat flux anomalies over the North Atlantic. However, the presence of cyclones doubles the magnitude of the 15 negative heat flux anomaly in the mid-North Atlantic. Similarly, the environmental flow anomaly determines the location of the SST cooling anomaly but the presence of cyclones enhances the SST cooling anomaly. Thus air-sea interactions play a major part in determining the extreme 2013/2014 winter season SST cooling anomaly. The environmental flow anomaly determines where anomalous heat flux and associated SST changes occur and the presence of cyclones influences the magnitude of those anomalies. 20
Multicriteria Course Mode Selection and Classroom Assignment Under Sudden Space Scarcity

Problem definition: Although physical (or “social”) distancing is an important public health intervention during airborne pandemics, physical distancing dramatically reduces the effective capacity of classrooms. Academic/practical relevance: During the COVID-19 pandemic, this presented a unique problem to campus planners who hoped to deliver a meaningful amount of in-person instruction in a way that respected physical distancing. This process involved (1) assigning a mode to each offered class as remote, residential (in-person), or hybrid and (2) reassigning classrooms under severely reduced capacities to the non-remote classes. These decisions need to be made quickly and under several constraints and competing priorities, such as restrictions on changes to the timetable of classes, trade-offs between classroom density and educational benefits of in-person versus online instruction, and administrative preferences for course modes and classrooms reassignments. Methodology: We solve a flexible integer program and use hierarchical optimization to handle the multiple criteria according to priorities. We apply our methods using actual Georgia Institute of Technology (GT) student registration data, COVID-19–adjusted classroom and laboratory capacities, and departmental course mode delivery preferences. We generate optimal classroom assignments for all GT classes at the Atlanta campus and quantify the trade-offs among the competing priorities. Results: When classroom capacities decreased to 20%–25% of their normal seating capacities, optimization afforded students 15.5% more in-person contact hours compared with no room reassignments (NRRs). Among sections with an in-person preference, our model satisfies 87% of mode preferences, whereas only 47% are satisfied under NRR. Additionally, in a scenario in which all classes are preferred to be delivered in person, our model can satisfy 90% of mode preferences compared with 37% under NRR. Managerial implications: Multiobjective optimization is well suited for classroom assignment problems that campus planners usually manage sequentially and manually. Our models are computationally efficient and flexible, with the ability to handle multiple objectives with different priorities and build a new class-classrooms assignment or optimize an existing one, and they can apply under normal or sudden capacity scarcity constraints.
N O T I C E THIS DOCUMENT HAS BEEN REPRODUCED FROM MICROFICHE. ALTHOUGH IT IS RECOGNIZED THAT CERTAIN PORTIONS ARE ILLEGIBLE, IT IS BEING RELEASED IN THE INTEREST OF MAKING AVAILABLE AS MUCH

Full disk measurements rer,orded 31 days before the Voyager 1 encounter with Jupiter by the radiometer (0.4-1.7 vm) of the infrared instrument. IRIS. indicate a geometric albedo of 0.274 t 0.013. The given error is an estimate of Systematic effects and therefore quite uncertain; the random error in the radiometer measurement is negligible. Combining this measurement with the Pioneer derived phase integral of 1.25 of Tomasko at al. (1978) and our error estimate of 0.1 yields a Jov:an Bond albedo of 0.343 t 0.032. Infrared spectra recorded at the same time by the Michelson interferometer (4-55W, along with a model extrapolation to low wave numbers not covered by the instrument, yield a thermal emission of (1.359 -' 0.014) 10-3 W cm-2 . This corresponds to an equivalent blackbody temperature of 124.4 t 0.3 K * in agreement with results of Ingersoll et al. (1975) and Erickson at al. ( 1 978), but lower than all other previous estimates. As in the case of the albedo measuremtnt the quoted errors in the emission measurement reflect estimates of systematic effects and are uncertain while the random component is negligible. From these measurements the internal heat flux of Jupiter is estimated to be (5.444 t 0.425) 10 -D W cm-2 . and the energy balance defined as the ratio of emitted thermal to absorbed solar energy is 1.668 t 0.085.
PRBM_A_308356 921..931

1Institute of Psychology, University of Opole, Opole, Poland; 2Faculty of Medicine, University of Technology, Katowice, Poland Purpose: Although research on orthorexia nervosa (ON) has developed in recent years, there exists a continuous need to develop valid tools to assess ON risk, according to strict diagnostic criteria. The present study aims to conduct Polish adaptation and validation of the Authorized Bratman Orthorexia Self-Test (ABOST), through a comparison of dichotomous and continuous Likert response scales. Participants and Methods: This cross-sectional study involved 472 people with mean age of 27 years (ranging between 18 and 78 years, M = 26.88, SD = 10.40). The survey included demographic questions and measures of orthorexia (the ABOST and ORTO-15), eating disorders (EAT-26), body mass index (BMI), obsessive–compulsive disorder (OCI-R), anxiety (GAD-7), and depression (PHQ-9). The following statistical tests were performed to explore the psychometric properties of the ABOST: descriptive statistics, Student’s t-test, Pearson’s correlation, Cronbach’s α reliability, exploratory factor analysis (EFA), and confirmatory factor analysis (CFA). Results: The ABOST using a five-point Likert scale for responses demonstrated good psychometric properties. The CFA goodness-of-fit indices confirmed the one-factor solution. Positive correlations were found between the ABOST and the ORTO-15, EAT-26, OCI-R, GAD-7, and PHQ-9. Women scored higher in the ABOST than men, while BMI was unrelated to the ABOST. Conclusion: The ABOST using the Likert scale provides a reliable and valid instrument to assess ON risk, as indicated by the face, structural, and convergent validity results. However, more research in various countries is needed, in order to verify the results of this study.
Corporate use of social media and market performance

Companies are being driven to use social media, however little is known about the impact of using these media on their performance. This study seeks to verify the relationship between the corporate use of social media and the market performance of Brazilian companies. To accomplish this, we will use ordinary least square (OLS) multiple linear regressions. The analysis period covers the years 2013 to 2017
A Novel Unsupervised Approach for Land Classification Based on Touzi Scattering Vector Model in the Context of Very High Resolution PolSAR Imagery

With the popularization of very high resolution polarimetric synthetic aperture radar image dataset, it is essential to re-investigate the classification scheme for 2-D land cases. The Touzi scattering vector model, a unique and roll-invariant decomposition solution, is employed to extract the scattering properties of different land covers. The parameters of Touzi decomposition act as input dataset for initial classification. A novel classifying algorithm is put forward by means of integrating the Touzi decomposition with conventional Wishart statistical models. Quantitative experiments are then conducted using uninhabited aerial vehicle synthetic aperture radar sample data for evaluating the performance of this new proposed approach. It can be concluded from the experimental results that the new proposed method is superior to the classical method in terms of producer accuracy, user accuracy, and overall accuracy.
Microbiological, serological and molecular diagnosis of abscess of withers in equine in the State of Pará

There are several infectious diseases that affect equines and can cause large economic losses in this sector and damage to animal welfare. In this species, abscessing lesions of a purulent character preferentially in the withers are strongly suggestive of brucellosis. However, few studies have been carried out on the disease in this species, making its identification and control difficult due to the lack of standardization in the interpretation of results. Therefore, samples of whole blood, serum and purulent secretion were collected from three horses. The animals came from the state of Pará. The diagnostic methods selected were the Rose-Bengal plate test (RBPT) and Polymerase Chain Reaction (PCR), for the negative molecular results for brucellosis, microbiological analysis were chosen. Although part of the samples were positive for brucellosis in serological tests, all of them showed negative results for PCR. In bacterial cultivation, species were isolated Streptococcus equi subsp. zooepidemicus, Enterococcus faecalis e Staphylococcus sciuri subsp. lentus. , which showed resistance to antibacterials, especially the E. faecalis isolate classified as MDR (multi drug resistant). In conclusion, the best form of diagnosis is the joint evaluation of several tests, both screening and confirmatory, in order to obtain a definitive diagnosis with assertiveness.
Borate reduces experimental supra-celiac aortic clamping-induced oxidative stress in lung and kidney, but fails to prevent organ damage

Background This study aims to investigate the effects of 2-aminoethoxydiphenyl borate (2-APB) on aortic clamping-induced lung and kidney tissue oxidation, tissue inflammation, and histological damage in a rat model. Methods A total of 28 adult female Wistar albino rats were randomly allocated to four equal groups: Control group, ischemia-reperfusion group, dimethyl sulfoxide group, and 2-APB group. Animals in the control group underwent median laparotomy. In the remaining groups, supra-celiac aorta was clamped for 45 min and, then, reperfusion was constituted for 60 min. The 2-APB (2 mg/kg) was administered before clamping. The remaining groups received saline (ischemia-reperfusion group) or dimethyl sulfoxide (dimethyl sulfoxide group). Kidney and lung tissue samples were harvested at the end of reperfusion. Results Aortic occlusion caused increased tissue total oxidant status and reduced total antioxidant status and glutathione levels in the ischemia-reperfusion and dimethyl sulfoxide groups. Tissue interleukin-1 beta and tumor necrosis factor-alpha levels, nuclear factor kappa beta activation, and histological damage severity scores were also higher in these groups. The 2-APB treatment eliminated the increase in total oxidant status and the decrease in total antioxidant status and glutathione levels. It also caused a decrease in the interleukin-1 beta levels, although it did not significantly alter the tumor necrosis factor-alpha levels, nuclear factor kappa beta immunoreactivity, and histological damage scores. Conclusion Borate exerted a beneficial antioxidant effect as evidenced by reduced oxidative stress; however, it did not inhibit nuclear factor kappa beta activation and prevent histological damage in supra-celiac aortic clamping-induced kidney and lung injury in rats.
Particle Coagulation of Emulsion Polymers: A Review of Experimental and Modelling Studies

ABSTRACT Particle coagulation, in conjunction with nucleation and growth, plays a significant role in determining the evolution of particle size distribution in emulsion polymerizations. Therefore, many modelling and experimental studies have been carried out to have a better understanding and control of the particle coagulation phenomenon in order to achieve high-quality as well as highly efficient industrial production. This article presents a review of modelling and experimental studies focused on the particle coagulation phenomenon in emulsion polymerizations. The state-of-art of particle coagulation modelling pertaining to emulsion polymerizations is discussed. Experimental studies concerned with latex coagulation processes are summarized next. The review finishes by discussing outstanding problems that need attention and sharing our perspectives on future developments.
Rahmatullah BMS-IDDT-2020-243-MS

Department of Biotechnology and Genetic Engineering, University of Development Alternative, Lamatia, Dhaka1207, Bangladesh; Biodiscovery Institute, School of Pharmacy, University of Nottingham, Nottingham, NG7 2RD, United Kingdom; CICECO-Aveiro Institute of Materials & Department of Medical Sciences, University of Aveiro, Aveiro, Portugal; School of Allied Health Sciences, World Union for Herbal Drug Discovery (WUHeDD), and Research Excellence Center for Innovation and Health Products (RECIHP), Walailak University, Nakhon Si Thammarat, Thailand; School of Pharmacy, University of Nottingham Malaysia Campus, Selangor, Malaysia
Comparison of Dynamic Responses of Parallel-Placed Adjacent High-Rise Buildings under Wind and Earthquake Excitations

Two parallel-placed adjacent high-rise buildings are often linked to each other through passive control devices for vibration mitigation purposes. The mitigation efficiency of these control devices mainly depends on the characteristics of relative dynamic responses, namely, opposite-sign and same-sign responses of the two buildings. The present research first identifies an opposite-sign response factor to estimate the time ratio of opposite-sign responses. Subsequently, a structure comprising two adjacent high-rise buildings (with different natural frequency ratios) subjected to both wind and earthquake excitations is analyzed. Wind-induced responses are evaluated based on wind loads obtained from wind tunnel tests, while earthquake responses are determined through a suite of 44 natural ground-motion records. The results indicate that opposite-sign factors of the displacement, velocity, and acceleration responses under wind loads, especially at across-wind direction, are larger than those under earthquake excitations, and opposite-sign response factors under wind loads are insensitive to variation of the natural frequency ratio of the two adjacent buildings compared with those under earthquake excitations. The conclusions of this research may be helpful for wind-resistant and antiseismic design of parallel-placed adjacent high-rise buildings.
MAKING STANCE EXPLICIT FOR SECOND LANGUAGE WRITERS IN THE DISCIPLINES: WHAT FACULTY NEED TO KNOW ABOUT THE LANGUAGE OF STANCE- TAKING

Expressing an authorial stance in contextually valued ways may be especially challenging for English as a Second Language (L2) writers (in addition, certainly, to many L1 writers), as the subtle ways that writers in the disciplines go about evaluating evidence and positioning the reader toward their views are largely tacit and therefore not often made explicit to students. In response to this problem, this chapter discusses ways that writing specialists can assist faculty in the disciplines to become explicitly aware of stance expressions in their students’ writing. Drawing on analysis of student writing in two disciplinary contexts (political theory and economics) as well as interviews with the course instructors, I offer examples of stance features that appear to be valued in these two contexts even though they run below the instructors’ fully conscious awareness. I then discuss ways that disciplinary faculty can be assisted to identify these features explicitly. The larger goal of this chapter is to argue for a way of reading students’ disciplinary writing that is sensitive to the details of stance-taking and to the languagerelated problems that many students experience when writing in the disciplines.
Chemical constituents, larvicidal activity and molluscicidal from fresh leaves of Alpinia zerumbet (Pers.) and Cymbopogon citratus (DC.) Stapf

Introduction: This study evaluated the chemical characterization, larvicidal activity and molluscicidal activity in front of the snail transmitting schistosomes (Biomphalaria glabrata) of the essential oils of Alpinia zerumbet and Cymbopogon citratus (DC.) Stapf. The essential oils (EOs) were extracted by hydrodistillation, with chemical characterization through Gas Chromatography coupled to mass spectrometry (GC-MS). The physical-chemical parameters were determined according to the Brazilian Pharmacopoeia. The toxicity test followed the bioassay with Artemia salina Leach, the EOs approved in this assay followed to evaluate their biological properties. Methodology: for molluscicidal activity, the methodology recommended by the WHO was performed, and the LC50 of the EOs was performed for their action in the face of the snail obtained by the Reed&Muench method. Both EOs showed low toxicity, and thus were evaluated for the biological properties larvicidal and molluscicidal . Alpinia zerumbet EO showed molluscicidal activity with LC50 of 40.63 mg·L-1 and Cymbopogon citratus EO 33.94 mg·L-1. Results: Both EOs showed larvicidal and molluscicidal potentials against the organisms tested, showing satisfactory results for their action. The results indicate that the evaluated EOs are composed of substances that promote and encourage their application due to their potential for molluscicidal and larvicidal biological activity.
PhotoCat Contents-2-2

Aims: We investigate the structural and morphological features as well as the sonophotocatalytic properties of (Ca1-xSrx)WO4 (x = 0.25; 0.50; 0.75 and 1) synthesized by the sonochemical method (SC). The as-synthesized samples were structurally characterized by X-ray diffraction (XRD), Rietveld refinement, micro-Raman, and Fourier-transform infrared (FT–IR) spectroscopies. Field-emission scanning electron microscopy (FE–SEM) and energy-dispersive X-ray spectroscopy (EDX) were used to analyze the morphological aspects and elemental chemical composition, respectively. Background: Currently, environmental issues have been one of the main concerns in the world, especially the contamination of freshwater supplies. Hence, environmental scientists have an enormous interest in developing efficient wastewater treatment technologies to remove harmful substances from contaminated water resources. In general, synthetic organic dyes and pigments, widely employed as coloring agents in leather or textile industries, severely impact the environment because of their toxic and carcinogenic nature. When discharged into water sources, such chemical pollutants have an irreversible and devastating impact on flora and fauna. As an alternative route to minimize these negative impacts, heterogeneous photocatalysis has emerged as a low-cost, safe, and versatile wastewater treatment approach. Objective: To analyze the effect of different strontium (Sr) contents (x = 0, 0.25, 0.50, 0.75, and 1) on the structural, morphological, optical, and sonophotocatalytic (SPC) properties of (Ca1-xSrx)WO4 samples. Methods: (Ca1-xSrx)WO4 (x = 0, 0.25, 0.50, 0.75, and 1) were synthesized by the sonochemical method at 40 oC for 3 h. Results: XRD patterns, Rietveld refinement data, and micro-Raman and FT–IR spectra proved that all samples are structurally organized in a scheelite-type tetragonal structure without deleterious phases. FE–SEM images showed the growth of flowerand spindle-like crystals. UV–Vis spectra indicated that the increase of Egap (from 4.68 to 4.94 eV) in (Ca1-xSrx)WO4 samples was proportional to Sr concentration inserted into the lattice. Conclusion: Among all samples, CaWO4 exhibited the highest SPC performance for the degradation of RhB solution under UV irradiation. When irradiated for 200 min, a degradation rate of around 96% was achieved for this sample. The ultrasound-assisted photocatalysis proved to be a promising approach for the degradation of organic dyes. A R T I C L E H I S T O R Y Received: November 09, 2020 Revised: February 05, 2021 Accepted: February 19, 2021 DOI: 10.2174/2665976X02666210405153830