Miracle-dz/UniFAR-FTUs huggingface dataset:
Manipulating Structural Graph Clustering

Structural graph clustering (SCAN) is a popular clustering technique. Using the concept of $\epsilon$-neighborhood, SCAN defines the core vertices that uniquely determine the clusters of a graph. Most existing studies assume that the graph processed by SCAN contains no controlled edges. Few studies, however, have focused on manipulating SCAN by injecting edges. Manipulation of SCAN can be used to assess its robustness and lay the groundwork for developing robust clustering algorithms. To fill this gap and considering the importance of the $\epsilon$-neighborhood for SCAN, we propose a problem, denoted as MN, for manipulating SCAN. The MN problem aims to maximize the $\epsilon$-neighborhood of the target vertex by inserting some edges. On the theoretical side, we prove that the MN problem is both NP-hard and APX-hard, and also is non-submodular and non-monotonic. On the algorithmic side, we design an algorithm by focusing on how to select vertices to join $\epsilon -$neighborhood and thus avoid enumerating edges to report a solution. As a result, our algorithm bypasses the non-monotonicity nature of the MN problem. Extensive experiments on real-world graphs show that our algorithm can effectively solve the proposed MN problem.
Reactogenicity to the mRNA-1273 Booster According to Previous mRNA COVID-19 Vaccination

The objective of this study was to assess the local and systemic adverse reactions after the administration of a COVID-19 mRNA-1273 booster between December 2021 and February 2022 by comparing the type of mRNA vaccine used as primary series (mRNA-1273 or BNT162b2) and homologous versus heterologous booster in health care workers (HCW). A cross-sectional study was performed in HCW at a tertiary hospital in Barcelona, Spain. A total of 17% of booster recipients responded to the questionnaire. The frequency of reactogenicity after the mRNA-1273 booster (88.5%) was similar to the mRNA-1273 primary doses (85.8%), and higher than the BNT162b2 primary doses (71.1%). The reactogenicity was similar after receiving a heterologous booster compared to a homologous booster (88.0% vs. 90.2%, p = 0.3), and no statistically significant differences were identified in any local or systemic reactions. A higher frequency of medical leave was identified in the homologous booster dose group vs. the heterologous booster dose group (AOR 1.45; 95% CI: 1.00–2.07; p = 0.045). Our findings could be helpful in improving vaccine confidence toward heterologous combinations in the general population and in health care workers.
Relativistic Turning Acceleration of Resonant Electrons by Coherent Whistler-Mode Waves in a Dipole Magnetic Field(RECENT RESEARCH ACTIVITIES)

[1] We report a very efficient process for accelerating high-energy electrons by coherent whistler mode waves in the Earth's dipole magnetic field, which we have found in our recent test particle simulations. The efficient acceleration process takes place for weakly relativistic seed electrons of a few hundred kiloelectronvolts. Under an assumption that the whistler mode wave packets are excited near the equatorial plane of the inner magnetosphere and propagate away from the equator, the acceleration process becomes irreversible. With a sufficiently long whistler mode wave packet of the order of 1 s, the energetic electrons are accelerated to a relativistic energy range of a few megaelectronvolts through a single resonant trapping process. We call this particular acceleration process relativistic turning acceleration (RTA), which could be a viable mechanism for increasing relativistic electron fluxes in the outer radiation belt. Necessary conditions for RTA are a relatively large amplitude of whistler mode waves, in the range of 50 to a few hundred picoteslas, and an initial kinetic energy of trapped electrons in the energy range of a few hundred kiloelectronvolts. The minimum energy of electrons accelerated by the RTA process and the maximum energy attained by it are derived analytically and verified by the test particle simulations.
Sharp Wavenumber-Explicit Stability Bounds for 2D Helmholtz Equations

Numerically solving the 2D Helmholtz equation is widely known to be very diﬃcult largely due to its highly oscillatory solution, which brings about the pollution eﬀect. A very ﬁne mesh size is necessary to deal with a large wavenumber leading to a severely ill-conditioned huge coeﬃcient matrix. To understand and tackle such challenges, it is crucial to analyze how the solution of the 2D Helmholtz equation depends on (perturbed) boundary and source data for large wavenumbers. In fact, this stability analysis is critical in the error analysis and development of eﬀective numerical schemes. Therefore, in this paper, we analyze and derive several new sharp wavenumber-explicit stability bounds for the 2D Helmholtz equation with inhomogeneous mixed boundary conditions: Dirichlet, Neumann, and impedance. We use Fourier techniques, the Rellich’s identity, and a lifting strategy to establish these stability bounds. Some examples are given to show the optimality of our derived wavenumber-explicit stability bounds.
Interpolation of Rainfall Data with Thin Plate Smoothing Splines - Part I: Two Dimensional Smoothing of Data with Short Range Correlation

Two dimensional thin plate smoothing splines were used to interpolate 100 daily rainfall values, with the degree of data smoothing determined by minimizing the generalised cross validation. Analyses were performed on the square roots of the rainfall values, permitting robust calibration of spatially distributed standard errors which are correlated with rainfall amount. Initial model calibration was made difficult by apparent short range spatial correlation in the data. This was overcome by removing one point from each of the ten closest pairs of data points, indicating that this correlation had a range of less than 10 km. A companion paper shows that the short range correlation can be associated with topographic effects. The error analyses were confirmed by comparing predictive accuracies on 367 withheld data
The Second Generation in Europe and the United States: How is the Transatlantic Debate Relevant for Further Research on the European Second Generation?

This introductory paper to the special issue of JEMS on the second generation in Europe reviews some of the key themes underpinning the growing interest in the second generation, and asks what ‘integration’ actually means in contemporary debates about immigration and settlement. The authors attempt to place these debates within their specific national contexts, in particular by applying US-developed theories of second-generation integration to Europe. In this way, we build on the embryonic transatlantic dialogue about which factors potentially account for different patterns of second-generation integration in different countries. Integration, in this sense, refers both to structural aspects such as educational and labour-market status as well as to a broader and at times fuzzier concept that includes ideas of culture, ethnic or religious identity and citizenship. The paper also sets the scene for the various articles in this special issue which together illustrate the thematic breadth of European-based research on the children of immigrants. We conclude by offering two theoretical avenues for future research on ethnic minority groups and their settlement patterns.
Transcriptomic Response of the Diazotrophic Bacteria Gluconacetobacter diazotrophicus Strain PAL5 to Iron Limitation and Characterization of the fur Regulatory Network

Gluconacetobacter diazotrophicus has been the focus of several studies aiming to understand the mechanisms behind this endophytic diazotrophic bacterium. The present study is the first global analysis of the early transcriptional response of exponentially growing G. diazotrophicus to iron, an essential cofactor for many enzymes involved in various metabolic pathways. RNA-seq, targeted gene mutagenesis and computational motif discovery tools were used to define the G. diazotrophicus fur regulon. The data analysis showed that genes encoding functions related to iron homeostasis were significantly upregulated in response to iron limitations. Certain genes involved in secondary metabolism were overexpressed under iron-limited conditions. In contrast, it was observed that the expression of genes involved in Fe-S cluster biosynthesis, flagellar biosynthesis and type IV secretion systems were downregulated in an iron-depleted culture medium. Our results support a model that controls transcription in G. diazotrophicus by fur function. The G. diazotrophicus fur protein was able to complement an E. coli fur mutant. These results provide new insights into the effects of iron on the metabolism of G. diazotrophicus, as well as demonstrate the essentiality of this micronutrient for the main characteristics of plant growth promotion by G. diazotrophicus.
Visual Social Semiotics on Malaysian Fishing Boat Capture News

Indonesia-Malaysia is two neighboring countries in Southeast Asia. The geographical proximity makes the two countries have a lot in common. However, this similarity does not guarantee that the two countries can coexist harmoniously. One of the problems in the relationship between the two countries is border-related issues, such as illegal fishing in the border area. This issue has been widely covered by the Indonesian mass media, including Metro TV and TVRI. This paper tries to see how Metro TV and TVRI reported the arrest of a Malaysian fishing boat near the border. This study uses a semiotic social visual analysis as a research method and the main theory of social reconstruction of reality. The research findings show Metro TV interprets this incident as illegal fishing and sovereignty violations. Meanwhile, TVRI interpreted this incident as illegal fishing and the achievements of the Indonesian marine police.
Distinct Peaks of UV-Absorbing Compounds in CDOM and Particulate Absorption Spectra of Near-Surface Great Barrier Reef Coastal Waters, Associated with the Presence of Trichodesmium spp. (NE Australia)

Distinct absorption peaks, with maxima at around 328 nm and a shoulder at 360 nm, were observed in the UV region of the absorption spectra for both the particulate and dissolved fractions of water samples collected in Keppel Bay (NE Australia) during the presence of sporadic Trichodesmium colonies. The largest absorption coefficients for these peaks were observed in samples collected in the near-surface waters (top 2–3 cm). Values approximately 3.5–6 times greater for aCDOM(328) and 13–36 times greater for ap(328) were observed in the near-surface samples compared to those collected from the top 20 cm of the water column at the same sites. Similar UV-absorption peaks observed in other studies have been attributed to the presence of mycosporine-like amino acids (MAAs). Increased UV absorption can affect both the magnitude of the absorption coefficients in the blue end of the visible region and the spectral slope of the exponential model commonly used to describe the CDOM absorption coefficient. This, in turn, can significantly affect the accuracy of satellite retrieved estimates of ocean colour products related to CDOM and particulate absorption coefficients. In tropical waters where Trichodesmium blooms are prevalent, regional ocean colour algorithms need to be developed using in situ bio-optical measurements from both the UV and visible regions of the spectra.
Short and Long-Term Voice and Swallowing-Related Quality of Life in Patients Who Underwent Total Laryngectomy and Tracheoesophageal Puncture

Background Voice and swallowing disorders can create a profound psychosocial impact on the patient’s quality of life. The focus of this study is to assess the psychosocial disabling effects on patients after total laryngectomy (TLP) using pre-validated surveys called the Voice Handicap Index 10 (VHI) for voice disorders and the Dysphagia Handicap Index (DHI) for swallowing disorders. Methodology This is a retrospective cohort study that was done on a total of 21 patients. The study was conducted at King Abdulaziz University Hospital between 2017 and 2022. The Cronbach’s alpha value was used to evaluate internal consistency reliability. The relationship between DHI, VHI, and demographic and clinical variables was analyzed by correlation analysis. A p-value of <0.05 was considered statistically significant, and all the tests were two-sided. Results The Cronbach’s alpha coefficient satisfied the internal consistency reliability for VHI and DHI for both total and their subscale scores. For DHI, the total score and emotional subscale obtained an alpha of greater than 0.9, indicating excellent internal consistency, whereas both physical and functional alpha scores indicated good internal consistency (α = 0.888 and α = 0.863, respectively). For VHI, the total score and physical subscale of the VHI had excellent internal consistency (α = 0.957 and α = 0.937, respectively), while the functional and emotional subscales had good internal consistency (α = 0.865 and α = 0.894, respectively). The total DHI scores, as well as the functional subscale scores, were significant (p = 0.033, p = 0.025, respectively) in terms of self-reported dysphagia severity. A moderately severe group (69.00 ± 19.17) had higher mean total scores, whereas severe individuals had higher subscale mean scores according to self-reported dysphagia severity. Self-reported dysphagia severity was as follows: normal (n = 3, 14.3%), mild (n = 4, 19%), moderate (n = 8, 38.1%), and severe (n = 6, 28.6%). Conclusions The disability caused by voice and swallowing disorders can be evaluated by VHI and DHI which have been statistically validated as reliable tools to assess the effects of dysphagia and dysphonia on quality of life. Patients after laryngectomy have higher mean DHI and VHI overall and functional subscale scores. However, this study failed to establish any relationship between clinical and demographical characteristics of the patients with DHI and VHI index.
Inequity in Access and Delivery of Virtual Care Interventions: A Scoping Review

The objectives of this review were to map and summarize the existing evidence from a global perspective about inequity in access and delivery of virtual care interventions and to identify strategies that may be adopted by virtual care services to address these inequities. We searched MEDLINE, EMBASE, and CINAHL using both medical subject headings (MeSH) and free-text keywords for empirical studies exploring inequity in ambulatory services offered virtually. Forty-one studies were included, most of them cross-sectional in design. Included studies were extracted using a customized extraction tool, and descriptive analysis was performed. The review identified widespread differences in accessing and using virtual care interventions among cultural and ethnic minorities, older people, socioeconomically disadvantaged groups, people with limited digital and/or health literacy, and those with limited access to digital devices and good connectivity. Potential solutions addressing these barriers identified in the review included having digitally literate caregivers present during virtual care appointments, conducting virtual care appointments in culturally sensitive manner, and having a focus on enhancing patients’ digital literacy. We identified evidence-based practices for virtual care interventions to ensure equity in access and delivery for their virtual care patients.
Attenuation of spinal anesthesia induced hypotension with granisetron in type I diabetic parturients: A randomized controlled clinical trial

ABSTRACT Background This study aimed to assess the safety and efficacy of intravenous granisetron as adjuvant therapy for spinal anesthesia-induced hypotension in type I diabetic parturients undergoing CS. Methods This double-blinded, parallel-group, randomized trial enrolled 68 adult parturients who were scheduled for CS under spinal anesthesia. The patients were randomly allocated to two groups (34 parturients each). In the granisetron (G) group, 1 mg of granisetron diluted in 10 mL of normal saline was administered intravenously 10 minutes prior to spinal anesthesia. While in the control (C) group, 10 mL of normal saline was administered in the same manner. The primary outcomes were total ephedrine consumption and frequency of use. Secondary outcomes included the total atropine consumption and frequency of use, nausea, vomiting, estimated intraoperative blood loss, patient satisfaction, Apgar score, and hemodynamic parameters. Results Group G had a significant reduction in the total ephedrine consumption (P = 0.009) and its frequency of use (P = 0.034). While the total atropine consumption and frequency of use, intraoperative blood loss, and patient satisfaction were not significantly different between the two groups. Nausea and vomiting were significantly reduced in group G. After 5 minutes of delivery, the Apgar score was significantly elevated in group G. The reduction of heart rate and hypotension was significantly lowered in group G. Conclusion In type I diabetic parturients, prophylactic use of granisetron can be effective in reducing ephedrine usage and attenuating the spinal anesthesia-induced hypotension during CS.
Comparing recent changes in the Arctic and the Third Pole: linking science and policy

ABSTRACT The rapid evolution of science compels renewal of a knowledge-based policy, particularly in cold regions. In the Arctic and Himalayas, which have undergone a significant climate change, there is a disconnect between scientific knowledge and the practices of policy. The rising air temperatures, decreasing ice and snow, increasing precipitation and plastic waste pollutants and the Atlantification of the Arctic Ocean by receiving warmer and saltier water from the Atlantic Ocean call for scientific research questions to strengthen the linkage between science and policy. The Arctic amplification can have remote impacts on other parts of the globe through oceanic and atmospheric teleconnections. Hence, researchers need to push the frontiers of scientific discoveries through multidisciplinary and collaborative approaches in the Arctic Ocean along with connections to the Third Pole – Himalayas. The overall objectives of this paper are to explore how a comparison of the Arctic and the Third Pole is valuable for understanding the Arctic and global biogeophysical processes in this epoch of anthropogenic climate change; provide a strong linkage between the Arctic scientific research and its relevance to society; and help advance a more sustainable future for the Arctic, the Third Pole and the globe.
Individual and Interpersonal Factors That Influence Dis-closure of Personal Identifiable Information on Social Net-Working Sites

This study aims to examine the influence of individual factors such as self-esteem and public con-sciousness and interpersonal factors such as the need for self-validation, social skills, and willingness to trust others on ‘personal identifiable information’ (PII) disclosure. The study used a quantitative research method. The study enrolled 375 male and female participants from Saudi Arabia. A closed-ended questionnaire was used to collect the data and analyzed using SPSS version 23. The study results predict that the following fac-tors: self-validation, public self-consciousness, willingness to trust others, and social skills influence PII dis-closure levels on social networking sites (SNS). This study identifies the most critical determinants and per-sonal or individual factors that affect the degree of PII disclosure on SNSs.
Techno-Economic Viability Assessment of a Household Scale Agricultural Residue Composite Briquette Project for Rural Communities in Nigeria

This study evaluated the technical and economic viability of a household scale composite briquette project. The objectives were to assess the quality of briquettes, estimate the cost of production, and determine the feasibility of the project. Briquettes were made from a blend of corncobs and the bark of oil palm trunk using a manual press. Production cost was estimated from the market price of commodities and specific economic indicators were used for feasibility analysis. Sensitivity analysis was performed on some essential input parameters that may affect the profitability of the project. Economic analysis revealed that the unit production cost of the briquettes was USD 0.16 per kg. The net present value was USD 6755.91 from the sale of briquettes at USD 0.26 per kg. An accounting profit is possible once briquette sales are above the break-even point of 7329.8 kg. Households could save about 25% from their per-capita expenditure on fuelwood when briquettes are utilized. Overall, the household briquette project is technically and economically viable in Nigeria. The significance of this study lies in the provision of a piece of baseline information to encourage local bio-energy development and serve as a guide for stakeholders in Nigeria with a potential interest in investing in briquette technology.
Pharmaceutical Cocrystals of Ethenzamide: Molecular Structure Analysis Based on Vibrational Spectra and DFT Calculations

Pharmaceutical cocrystals can offer another advanced strategy for drug preparation and development and can facilitate improvements to the physicochemical properties of active pharmaceutical ingredients (APIs) without altering their chemical structures and corresponding pharmacological activities. Therefore, cocrystals show a great deal of potential in the development and research of drugs. In this work, pharmaceutical cocrystals of ethenzamide (ETZ) with 2,6-dihydroxybenzoic acid (26DHBA), 2,4-dihydroxybenzoic acid (24DHBA) and gallic acid (GA) were synthesized by the solvent evaporation method. In order to gain a deeper understanding of the structural changes after ETZ cocrystallization, terahertz time domain spectroscopy (THz-TDS) and Raman spectroscopy were used to characterize the single starting samples, corresponding physical mixtures and the cocrystals. In addition, the possible molecular structures of ETZ-GA, ETZ-26DHBA and ETZ-24DHBA cocrystals were optimized by density functional theory (DFT). The results of THz and Raman spectra with the DFT simulations for the three cocrystals revealed that the ETZ-GA cocrystal formed an O−H∙∙∙O hydrogen bond between the -OH of GA and oxygen of the amide group of the ETZ molecule, and it was also found that ETZ formed a dimer through a supramolecular amide–amide homosynthon; meanwhile, the ETZ-26DHBA cocrystal was formed by a powerful supramolecular acid–amide heterosynthon, and the ETZ-24DHBA cocrystal formed the O−H∙∙∙O hydrogen bond between the 4-hydroxy group of 24DHBA and oxygen of the amide group of the ETZ molecule. It could be seen that in the molecular structure analysis of the three cocrystals, the position and number of hydroxyl groups in the coformers play an essential role in guiding the formation of specific supramolecular synthons.