Miracle-dz/UniFAR-FTUs huggingface dataset:
Depth-integrated free-surface flow with non-hydrostatic formulation

This dissertation presents the formulation of depth-integrated wave propagation and runup models from a system of governing equations for two-layer non-hydrostatic flows. The conventional two-layer non-hydrostatic formulation is re-derived from the continuity and Euler equations in non-dimensional form to quantify contributions from nonlinearity and dispersion and transformed into an equivalent integrated system, which separately describes the flux and dispersion-dominated processes. The formulation includes interfacial advection to facilitate mass and momentum exchange over the water column. This equation structure allows direct implementation of a momentum conserving scheme and a moving waterline technique to model wave breaking and runup without interference from the dispersion processes. The non-hydrostatic pressure, however, must be solved at the layer interface and the bottom simultaneously from the pressure Poisson equation, which involves a non-symmetric 9-band sparse matrix for a two-dimensional vertical plane problem. A parameterized non-hydrostatic pressure distribution is introduced to reduce the computational costs and maintain essential dispersion properties for modeling of coastal processes. The non-hydrostatic pressure at mid flow depth is expressed in terms of the bottom pressure with a free parameter, which is optimized to match the exact linear dispersion relation for the water depth parameter up to kd = 3. This reduces the integrated two-layer formulation to a hybrid system with unknown nonhydrostatic pressure at the bottom only and a tridiagonal matrix in the pressure Poisson equation. The hybrid system reduces to a one-layer model for a linear distribution of the non-hydrostatic pressure.
Evaluation of Surgical Outcome of Treatment of Anterior Cruciate Ligament Reconstruction by Hamstring Graft

Anterior Cruciate Ligament (ACL) reconstruction by surgery is an important issue for knee stability. The purpose of this study was to evaluate the surgical outcomes after ACL reconstruction using four-strand hamstrings graft. This experimental study was conducted in the department of orthopedics at Bangabandhu Sheikh Mujib Medical University, Dhaka from January 2012 to December 2014 for a period of two years. Patients presented with a symptomatic unilateral ACL rupture who were underwent ACL reconstruction by using Hamstrings graft were selected as study population. All surgery was performed by the same surgeon and the procedure was arthroscopically assisted. Operation was performed at least three weeks after initial trauma. All patients were assessed by independent examiner before surgery, and after operation at 6 months, 12 months and then annually by clinically. A total number of 35 patients were treated with hamstrings tendon as a graft. The mean age (±SD) was 26.97±10.10 years with majority of younger (15-30 years). Maximum (71.4%) patients were male and more than one-third (37.1%) were student followed by 25.7% service holders. Monthly family income of the patients was USD 594.5 (±258.1). Tegner score to assess the knee activity increased significantly from 2.1 (±1.0) in preoperative to 5.8 (±1.5) in post-operative. Regarding outcome of the operation, more than half (51%) found excellent and 46% cases had a good result. Surgical outcome after ACL reconstructions by hamstrings graft is outstanding. Extensive training on this procedure might accelerate the performance of orthopedic surgeons. of two years. Inclusion criteria were: symptomatic unilateral ACL rupture and ACL injury associated with meniscus and chondral lesion (1&2) patients willing to undergo ACL reconstruction by using hamstrings graft, were selected as study population. Exclusion criteria were: ACL rupture associated with posterior cruciate ligament injury, and lateral collateral ligament injury, previous ligament reconstruction, stage 3 & 4 chondral lesion and advanced osteoarthritis of knee were excluded from this study. All patients were diagnosed clinically, Magnetic Resonance Imaging (MRI) and arthroscopically during surgery. All surgery was performed by the same surgeon. The surgical procedure was arthroscopically assisted. Operation was performed at least three weeks after initial trauma.
Modelling the transfer, transformation and retention of silica along aquatic continuums : an upgraded deterministic approach

The watershed-based deterministic model Riverstrahler, developed to simulate ecological river functioning and nutrient delivery at the river outlet, has been improved regarding algal dynamics and silica cycle representation. Silica is present in the model in two forms: dissolved (DSi) and particulate / biogenic (BSi). Three groups of diatoms are now considered, spring and late summer planktonic diatoms and benthic diatoms, in order to better represent dissolved silica uptake spatially (benthic diatoms develop mostly upstream) and temporally (the summer diatom bloom is composed of diatoms with different characteristics including those of the spring species). The diatom groups differ in their physiological parameters, such as growth rate, optimal temperature, etc., and the sensitivity of the model to these parameters is explored. For biogenic silica, not only diatoms are represented, but phytolith inputs to the watershed are also included, as well as a comprehensive representation of BSi transport, dissolution, deposition and diagenesis. A budget of silica delivery at the river outlet is established from the model results for two hydrologically different years (dry-1991 and wet-2001), showing the dependence of silica transfer on hydrological conditions. In fact, although silica specific fluxes are in the range of those typical of temperate regions, dissolved silica export from the Seine basin can vary from 552 kg Si/km/year in 1991 to three times this amount in a wet year such as 2001 (1721 kg Si/km/year). Biogenic silica in total silica export can vary from about 7% in the upstream network, to 29% at the river outlet as in 1991. The integration of new silica-related processes in the model allows a synoptical simulation of multi-form (dissolved and particulate) and multi-nutrient (N and P being already represented) delivery to the coastal zone.
Risk Management and Data Needs: A State of the Practice Survey of State Highway Agencies

Risk management analysis is one of the new requirements under MAP-21 that separates transportation asset management programs from business as usual for the state departments of transportation (DOTs). Based on this requirement, each agency will discuss the concept of risk and how it should be incorporated into its transportation asset management program as well as how it informs maintenance practices, asset replacement or rehabilitation, and emergency management and response planning. This will require an agency to provide a list of risk exposures and document its system-wide risk management strategy. This paper presents the results of a state of the practice survey of how agencies are developing their risk-based asset management plan and discusses recommendations for future research. The results show that state highway agencies are increasingly adapting the way they do business to include explicit considerations of risks. At the moment, this consideration of risk is not linked to data, and as a result most agencies do not have a data driven way of tracking risk and updating their risk exposures. The significance of the results highlights the need for further research on data driven risk management and to synthesize methodologies for integrating risk assessment into an agency’s decision-making process.
Effects of Vibration Training on Cognition and Quality of Life in People with Multiple Sclerosis

Background: Multiple sclerosis (MS) detrimentally affects cognition and quality of life (QOL). Interventions that can improve cognitive deficit and QOL in people with MS are desired. This pilot study investigated the possible effects of vibration training on improving cognition and QOL in people with MS. Methods: Eighteen adults with MS were randomized into two groups: training and control. The training group underwent 6 weeks of vibration training, and the control group maintained their normal lifestyle throughout the study. In both groups, before and after the training course, the disability status was evaluated by the Patient-Determined Disease Steps scale and the Multiple Sclerosis Functional Composite (MSFC), cognitive function was assessed by the Behavior Rating Inventory of Executive Function (BRIEF) and the Selective Reminding Test (SRT), and QOL was gauged by the 36-item Short Form Health Survey (SF-36). Results: The training was well accepted by the participants, and no major adverse event was reported. All participants finished the entire protocol. Compared with the control group, after the training the training group showed greater improvements in MSFC score, Metacognition Index score of the BRIEF, SRT score, and physical domain score of the SF-36. Conclusions: These results suggest that vibration training could be an effective alternative training paradigm to enhance cognition and QOL in people with MS, and they provide an encouraging base to conduct a large-scale clinical trial. Int J MS Care. the of a on QOL in people with on a adopted an 8-week training The vibration amplitude and bout duration were fixed at 2 and 1 minute, respectively, in previous studies. In the present the vibration amplitude and bout duration gradually increased from 2 and 1 minute, respectively. the training dosage is closely associated with the amplitude and the bout duration and that the training dosage is strongly related to the training effect, that the 6-week training would and QOL people The this the effectiveness This study used a two-arm randomized controlled design (Figure which is published in the online version of this article at ijmsc.org). The training group underwent a 6-week vibration training. The control group did not receive training but maintained their regular lifestyle throughout the study. Before and after the training course, both groups were evaluated for their disability status, cognitive function, QOL, and physical activity level.
Radiation reaction in strong fields from an alternative perspective

Current classical theory of radiation reaction has several deficiencies such as "runaway solutions" and violation of causality. The Landau-Lifshitz approximation to the exact equation introduced by Lorentz, Abraham and Dirac is widely used, though questions remain regarding its domain of validity. This thesis explores an alternative treatment of the motion of a radiating electron, based on an equation first proposed by Ford and O'Connell. A general condition is found for solutions of this equation to deviate from those of Landau-Lifshitz. By exploring radiation reaction effects on a particle colliding with an ultra-intense laser pulse we show that the regime where there is a significant deviation of these two approaches can never be reached with existing or proposed laser facilities. The methods used to explore single particle interaction with an intense laser pulse are extended to describe the interaction of a particle bunch with various realistic laser pulses. We find that the interaction leads to a decrease in average momentum and relative momentum spread. However, the decrease appears to be independent of the length of the pulse and depends only on the energy in the pulse regardless of how it is distributed. Radiation reaction effects occuring during the scattering of an electron by a heavy, highly-charged nucleus are studied. Radiation reaction is seen to affect the particle's motion. We find noticeable differences between the predictions of the Ford-O'Connell and Landau-Lifshitz equations, albeit in regimes where quantum effects would be important.
ANTIFUNGAL UTILIZATION AND OUTCOME EVALUATION IN A TERTIARY HOSPITAL

ABSTRACT Objective: The risk of fungal infection is one of the many concerns of patients admitted for chronic illness. The increase in fungal infection causes excessive morbidity and mortality. Despite the use of antifungals, the outcome of patients remains challenging. The study was performed to identify factors affecting the outcome of antifungal use. Methods: A retrospective study was carried out in a local tertiary hospital for the past 1 year. Patients prescribed antifungals were included. Results: A total of 145 patients who had been prescribed with antifungal agents within the past year were included in the study. It was noted that patients infected with fungi were mostly elderly patients (n=83, 57.2%). A majority of the patients (n=67, 46.2%, p<0.001) were diagnosed with or suspected to have systemic fungal infection compared to urinary fungal infection (n=31, 21.4%), oral fungal infection (n=20, 13.8%), pulmonary fungal infection (n=19, 13.1%), and others (n=8, 5.5%). As such, intravenous antifungal was the most commonly prescribed dosage form (n=88, 60.7%, p<0.001). The mortality rate of patients with fungal infection was 35.9% (n=52). No significant factors were observed to affect the clinical outcome of patients. However, factors affecting survival outcome in patients treated for fungal infection were targeted treatment (p=0.036), less number of medications (p<0.001), and a higher number of antifungals prescribed (p=0.010). Conclusion: A more comprehensive review of medication is required to ensure appropriate treatment is given to patients with fungal infection. Keywords: Antifungal, Fungal infection, Outcome.
Strength-based interventions: Their importance in application to the gifted

: Positive psychology has revived psychology’s abandoned interest in the study of morally positively valued traits (the so-called character strengths) and virtues. We review lit- erature generated on strength-based approaches and focus on applications in the so-called positive psychology interventions. There seems to be great potential in this approach for research in the field of giftedness and, of course, also when practically working with gifted children and adolescents. We highlight some ideas for future research directions. Abstract Positive psychology has revived psychology’s abandoned interest in the study of morally positively valued traits (so-called character strengths) and virtues. We review literature generated on strength based approaches and focus on strength based interventions. There seems to be great potential in this approach for research in the field of giftedness and, of course, also when practically working with gifted children and adolescents. We highlight some ideas for future research directions.
University of Birmingham Eps8 controls Src- and FAK-dependent phenotypes in squamous carcinoma cells

Eps8 is an actin regulatory scaffold protein whose expression is increased in squamous cell carcinoma (SCC) cells. It forms a complex with both focal adhesion kinase (FAK, also known as PTK2) and Src in SCC cells derived from skin carcinomas induced by administration of the chemical DMBA followed by TPA (the DMBA/TPA model). Here, we describe two new roles for Eps8. Firstly, it controls the spatial distribution of active Src in a FAK-dependent manner. Specifically, Eps8 participates in, and regulates, a biochemical complex with Src and drives trafficking of Src to autophagic structures that SCC cells use to cope with high levels of active Src when FAK is absent. Secondly, when FAK is expressed in SCC cells, thereby meaning active Src becomes tethered at focal adhesion complexes, Eps8 is also recruited to focal adhesions and is required for FAK-dependent polarization and invasion. Therefore, Eps8 is a crucial mediator of Src- and FAK-regulated processes; it participates in specific biochemical complexes and promotes actin re-arrangements that determine the spatial localization of Src, and modulates the functions of Src and FAK during invasive migration.
The Effects of Smart Factory Operational Strategies and System Management on the Innovative Performance of Small- and Medium-Sized Manufacturing Firms

: This study aims to determine the effects of smart factory system management and operational strategies on the innovative performance of small- and medium-sized manufacturing ﬁrms. To this end, we administered an empirical survey to 222 hands-on workers who operate smart factories in small- and medium-sized Korean ﬁrms. The collected data were analyzed using structural equation modeling and the results showed that the enterprise resource planning (ERP), quality management, ethical management, and productivity management systems had positive effects on innovative performance. The effect of operational strategies on innovative performance was not veriﬁed. Consequently, small- and medium-sized ﬁrms should focus on establishing ERP systems, which lead to system establishment, standardization of work processes, CEO support and attention, and increase user recognition levels for raising innovative performance.
Lack of truncated IFITM3 transcripts in cells homozygous for the rs12252-C variant infection

IFITM3 protein is known to restrict the entry of a range of enveloped viruses. The 30 single nucleotide polymorphism rs12252-C within IFITM3 has been shown to be 31 associated with severe influenza A virus infection. It has been suggested that rs12252- 32 C results in expression of a truncated IFITM3 protein lacking the first 21 amino acids. 33 By performing high throughput RNA sequencing on primary dendritic cells and 34 peripheral blood mononuclear cells isolated from pandemic H1N1 influenza & HIV-1 35 infected patients we show that full-length IFITM3 mRNA is dominantly expressed 36 (>99%) across all rs12252 genotypes. Full-length IFITM3 protein can be detected in 37 all genotypes.
Prevalence of malnutrition and associated risk factors among under-five children in Amhara Region, Ethiopia: evidence from 2016 Ethiopian Demographic and Health Survey

Background Childhood malnutrition is the most widely prevalent among under-five children in Amhara Region, Ethiopia. This study intended to explore the major determinants of malnutrition and its association with anemia among under-five children in Amhara Region, Ethiopia.Methods The data from the 2016 Ethiopian Demographic and Health Survey were used. A total of 977 under-five children were included in this analysis. A multivariable binary logistic regression analysis was used at a 5% level of significance to determine the individual- and community-level factors associated with childhood malnutrition. Results The prevalence of stunting, wasting, and underweight were 46.3%, 9.8%, and 28.4%, respectively. About 23.1% of children were both stunting and underweight, 7.3% were both underweight and wasting, and only 4.5% of children had all the three conditions. Among the factors considered in this study, Age of child in months, size of child at birth, mother highest education level, sex of household head, sources of drinking water, and type of toilet facility were significantly associated with malnutrition in Amhara Region. Conclusion Malnutrition among under-five children was one of the public health problems in the Amhara Region. The influence of these factors should be considered to develop strategies for reducing malnutrition in Amhara Region. Finally improving the living standards of the children is important to get better health care, to enhance the child’s nutritional status, and reduce child mortality.
Effect of egg quality traits on fertility and hatchability of Vanaraja parents

A study was undertaken to assess the effect of egg quality traits on the fertility and hatchability of Vanaraja Parents maintained in the poultry farm of the Poultry seed project of College of Veterinary Science and Animal Husbandry, Anjora, Durg (Chhattisgarh). A total of 150 numbers of eggs from each pen were selected for setting in a single-stage incubator for 48 th , 49 th , 52 nd , and 55 th week. Eggs were grouped and divided into three groups, i.e., below average, average, and above-average, according to their weight and shape index. Eggs were candled twice during incubation, i.e., on the 7th and 18th days. Fertility percent, hatchability percent on TES (total egg set basis), and FES (fertile egg set basis) calculated. The findings have shown that the highest fertility rate observed for average (53 – 61g) egg weight group were 90.12 %. However, significantly ( P <0.01) highest overall hatchability on Fertile Egg Set (FES) basis was observed in the average group that is 89.22%. On the basis of their shape index, there is a significantly highest ( P <0.01) fertility rate was observed in the average group that is 97.47%. The average hatchability on the Total Egg Set (TES) basis irrespective of different ages of the eggs of the average group (81.75%) was highly significant ( P <0.01). And the average hatchability on the Fertile Egg Set (FES) basis irrespective of different ages of the eggs of average group 89.37% was highly significant ( P <0.01). The results indicate that Vanaraja eggs having a normal oval shape and rounded shape hatch better as compared to the cylindrical eggs.
Influence of Moisture Content and Seed Dimensions on Mechanical Oil Expression from African Oil Bean ( Pentaclethra macrophylla Benth) Seed

Purpose: New low-cost oilseeds are needed to meet an ever-increasing demand for oil for food, pharmaceutical, and industrial applications. African oil bean seed is a tropical crop that is underutilized and has high oil yields, but there have been no studies conducted on its mechanical oil expression up to now. The objective of this work was to investigate the effect of moisture content and seed dimensions on mechanical oil expression from the seeds. Methods: Fresh oil bean seeds were procured, de-hulled, and cleaned. Initial seed moisture content, obtained in accordance with the ASAE standard, was 12% dry basis (db). The seeds were further conditioned by dehydration and rehydration prior to oil expression to obtain four other moisture levels of 8, 10, 14, and 16% db. The major diameter of the seeds was measured using digital vernier calipers, and the seeds were classified into size dimensions (< 40, 41-45, 46-50, 51-55, and > 55 mm). The oil yield and expression efficiency were obtained in accordance with standard evaluation methods. Results: The highest oil yield and expression efficiency (47.74% and 78.96%, respectively) were obtained for a moisture content of 8% db and seed dimensions of < 40 mm, while the lowest oil yield and expression efficiency (41.35% and 68.28%, respectively) were obtained for a moisture content of 14% db and seed dimensions between 51-55 mm. A mathematical model was developed to predict oil yield for known moisture content and seed dimensions, with a coefficient of determination R 2 of 95% and the confidence level of the predictive model of 84.17%. The probability of prediction F ratio showed that moisture content influence was more significant than seed dimensions. Conclusions: The higher the moisture content and larger the seed dimensions, the lower the oil yield from African oil bean seeds. Oil yield, Seed dimensions