Miracle-dz/UniFAR-FTUs huggingface dataset:
Clinical Study to Evaluate the Prevalence of TMD Before and After Delivery of Complete Denture

Temporomandibular disorder (TMD) is a broad term that encompasses number of clinical problems including the temporomandibular joints, the masticatory musculature and related structures, or both. The etiology of TMD is ambiguous since the signs and symptoms which exist in patients with natural teeth may also being observed in edentulous patients. Thus, TMD is a multifactorial problem with varying symptoms combinations and rates. Relationship between removable complete dentures and tempromandibular joint disorder in different gender and age groups. A total of 30 patients (15 female and 15 male) who submitted to Prosthodontics Department, College of Dentistry, Al-Mustansiriyah University to make a new complete denture. The age of participants ranges from (40-80) years with the mean age (65.9) years. Two clinical examiners conducted the patient’s examination; the first examiner takes on a questionnaire to identify the TMD symptoms signs and. Clinical examination of the patients was assessed through part I, II of research diagnostic criteria pre and post one and two months of applying the prosthesis. The clinical evaluation of prosthesis done by the second clinical examiner related to (retention, stability, fitness, occlusion and centric relation) was evaluated twice at predetermined intervals of 1 and 2 months after construction and delivery of denture. Evaluation performed by using Dawson's bimanual technique and recorded within clinical case sheet for complete denture records. The present study shows that the highest frequency of TMD obtained in age group of 70-80 years old followed by age group of 60-69 years old at all intervals, internal derangement (ID frequency) significantly higher in females than male patients (p=0.02). There is significant statistical difference regarding the Myofacial pain dysfunction (MPD) frequency according to the time of using the dentures, those patients with Diabetes Mellitus (DM) formed the highest percentage (39.1%) of those whom presented with MPD followed by those with Hypertension (HT) (32%) and those with history of HT and DM represent (17.4%) only The results also illustrated that prosthesis properties (retention, stability, fitness, occlusion and centric relation) show significant relation with TMDs improvement post one and two months. Most patients with complete denture perceived improvement in the sign and symptoms of TMDs.
MEDIA PEMBELAJARAN BERBASIS WEB PADA MATA PELAJARAN BIOLOGI KELAS X

Penelitian ini bertujuan untuk mengembangkan media pembelajaran berbasis web pada mata pelajaran biologi kelas X. Metode penelitian yang digunakan adalah penelitian pengembangan dengan menggunakan model prosedural. Model yang dilakukan dengan tahapan prosedur pengembangan yaitu (1) Tahap perencanaan berupa analisis kebutuhan, menyusun Garis Besar Isi Media (GBIM) dan Jabaran Materi (JM), menyusun naskah (storyboard); (2) Tahap Produksi berupa persiapan, pelaksanaan, penyelesaian; (3) Tahap Evaluasi berupa evaluasi pramaster, revisi, uji lapangan. Hasil penelitian ini menunjukkan bahwa media pembelajaran berbasis web yang dikembangkan pada mata pelajaran biologi kelas X sudah layak untuk digunakan dalam pembelajaran di sekolah. Berdasarkan beberapa tahapan uji coba, media pembelajaran berbasis web dikategorikan valid dengan dengan kriteria baik. Penelitian pengembangan media pembelajaran berbasis web ini diharapkan dapat menjadi media pembelajaran mata pelajaran biologi serta dapat bermanfaat bagi guru, siswa, dan peneliti lanjutan.
A look at Singapore hostess bars through the lens of Negri and Chakrabarty

This article, written in a confessional, autoethnographic style, explores the author’s experiences over a number of years with Singapore hostess bars/pubs. The research method is participant-observation of practices, discourses, pricing models and customer demographics, and knowledge gained from hostesses, bar managers and musicians. The law aspect of the article is critiquing the lack of citizenship rights and marriage rights for foreign workers in Singapore such as pub hostesses and construction workers. It also looks at the working conditions and cultures of the pubs, and describes the alienation and emotional labour involved in delivering heavily racialized and gendered services. Neither Filipina/Vietnamese hostesses nor Europeans have established places within the Singapore citizenship narrative or in government policy, which relies upon the hegemonic CMIO (Chinese, Malay, Indian, Others) Model. Filipina and Vietnamese pub hostesses do not fit neatly within this model and are hindered by the power of the narrative.
Mercury isotope compositions across North American forests

Forest biomass and soils represent some of the largest reservoirs of actively cycling mercury (Hg) on Earth, but many uncertainties exist regarding the source and fate of Hg in forest ecosystems. We systematically characterized stable isotope compositions of Hg in foliage, litter, and mineral soil horizons across 10 forest sites in the contiguous United States. The mass‐independent isotope signatures in all forest depth profiles are more consistent with those of atmospheric Hg(0) than those of atmospheric Hg(II), indicating that atmospheric Hg(0) is the larger source of Hg to forest ecosystems. Within litter horizons, we observed significant enrichment in Hg concentration and heavier isotopes along the depth, which we hypothesize to result from additional deposition of atmospheric Hg(0) during litter decomposition. Furthermore, Hg isotope signatures in mineral soils closely resemble those of the overlying litter horizons suggesting incorporation of Hg from litter as a key source of soil Hg. The spatial distribution of Hg isotope compositions in mineral soils across all sites is modeled by isotopic mixing assuming atmospheric Hg(II), atmospheric Hg(0), and geogenic Hg as major sources. This model shows that northern sites with higher precipitation tend to have higher atmospheric Hg(0) deposition than other sites, whereas drier sites in the western U.S. tend to have higher atmospheric Hg(II) deposition than the rest. We attribute these differences primarily to the higher litterfall Hg input at northern wetter sites due to increased plant productivity by precipitation. These results allow for a better understanding of Hg cycling across the atmosphere‐forest‐soil interface.
The effect of different levels of vitamin C on performance, carcass characteristics, digestive organs, immunity, blood parameters, liver enzymes, cecal microflora, evaluation of meat taste and fatty acid profile of breast meat of broilers

The objective of this experiment was to investigate the effect of different levels of vitamin C on performance, carcass characteristics, immunity, blood parameters, cecal microbial flora, evaluation of meat taste and fatty acid profile of Arbor Acres commercial strain broilers. In order to investigate the different levels of vitamin C, 120 one-day-old male broilers of the Arbor Acres commercial strain were used in a completely randomized design. In this way, three different levels of vitamin C (0, 250 and 50 mg/kg diet) were tested with 4 repetitions with 10 chicks in each repetition for 42 days. Average daily weight gain, average daily feed intake and feed conversion ratio were determined. At the age of 42 days, 2 chicks were randomly selected from each replication and the characteristics of carcass components, blood parameters, liver enzymes, taste evaluation and fatty acid profile of breast meat were measured. The evaluation of the immune system was evaluated by measuring the antibody titers against the Newcastle vaccine, anvian influenza and sheep red blood cells (SRBC) and were analyzed with SPSS statistical software. The results showed that in the whole period, no statistical difference was observed between the treatment groups in terms of feed consumption and weight gain and feed conversion ratio (P>0.05), The effect of vitamin C on carcass and intestinal characteristics was not significant, except for the relative weight of the breast (P>0.05). The effect of vitamin C on blood parameters, except for HDL and total cholesterol which were increased were not affected by experimental treatments. Liver enzymes including creatine phosphokinase and lactate dehydrogenase in broilers receiving experimental treatments were increased by higher levels of vitamin C in the diet (P<0.05). The examination of the immune system of broilers showed that the comparison of the average amount of white and red blood cells, hemoglobin, HTC, MCV, MCH and MCHC was not affected by different levels of vitamin C in the diet (P>0.05). However, the percentage of lymphocytes and heterophils was affected by different levels of vitamin C (P<0.05). The amount of antibody titer against Newcastle virus, influenza and SRBC and organs related to the immune system was not affected by experimental treatments (P>0.05). The effect of vitamin C on taste evaluation traits showed that general acceptance and chewing ability were different in all three treatment groups (P<0.05), but other traits were not affected by different levels of vitamin C (P>0.05). The effect of vitamin C on the fatty acid profile of breast meat showed C12:0 was unchanged in the 3 treatment groups, but C14:0, C16:0, C18:0, C18:3 decreased with increasing consumption of vitamin C. The present research suggests that use of 250 mg of vitamin C per kg of diet of broilers of the Arbor Acres strain may have potential economic benefits.
Effects of selling through an auction market on physiological variables in beef calves

In Chile, selling cattle through auction markets is common, and involves various stressful events. The objective of this study was to determine the effects of selling weaned beef calves through an auction market on indicators of physiological stress. Considering that transportation is invariably linked to any commercialization procedure, we compared the effects of exposing calves to transport and sale through an auction market versus transporting them directly between farms. Twenty calves of 175 (+/-37.5) kg live weight were transported from their origin farm to an auction market (2.5 h journey), where 10 calves were unloaded and exposed to regular handling within the market (unloading, sorting, regrouping, penning, sale yard showing) and thereafter loaded and transported back to the farm (TM). The remaining 10 calves were not unloaded at the market and were immediately transported back to the farm, simulating a direct sale (TD). Data collection (blood samples, body temperature, and live weight) was performed at the farm in both groups before loading (initial, 0 h), at the end of the process, after unloading TM calves back on the farm (after unloading, 12 h), and during recovery at 24, 48, and 72 h after the initial sampling. We used mixed-effects models to compare treatments and samplings. No differences were found between treatments in terms of live weight loss, maximum eye temperature, plasma beta-hydroxybutyrate, and serum cortisol concentrations. The rectal temperature was higher (p < 0.05) in TM after treatment and remained higher (p > 0.05) in the samples than in TD. Calves that passed through the market showed higher (p < 0.05) plasma CK activity after unloading (12 h) than did those that did not. The mean glucose concentration increased (p < 0.05) at 12h and remained higher than the initial value (0 h) in both the calf groups. This was a preliminary study, and according to the results, experiments should be repeated to test more animals under different situations and premises.
Agroforestry and Soil Health: Linking Trees, Soil Biota, and Ecosystem Services

A signifi cant and increasing proportion of the Earth’s land area is covered by crop and range lands. Agricultural landscapes hold a large proportion of the world’s biodiversity but the relative contribution of each land management type to conservation of biodiversity and the maintenance of ecosystem service delivery is poorly understood ( Jackson et al. 2005 ). Ecosystem services can be classifi ed into those associated with the provision of goods (e.g. food, fi bers, and fresh water), those that support and regulate ecosystem function (e.g. climate regulation, disease control, soil formation, and nutrient cycling), and those cultural services that are not associated with material benefi ts (e.g. recreation, spiritual, and aesthetic value) ( MEA 2005 ). Agricultural ecosystems both require and generate ecosystem services and may enhance or degrade natural capital through time depending on how they are managed. Soil health is a key indicator of the state of natural capital, and is considered here as an integrative property that refl ects the capacity of soil to respond to agricultural management by maintaining both the agricultural production and the provision of other ecosystem services ( Kibblewhite et al. 2008 ). Soil organisms contribute to a wide range of ecosystem services that are essential to the functioning of natural and managed ecosystems ( Wall 2004 ). Evidence has shown that there is a strong link between organisms aboveand belowground ( Wardle et al. 2004 ), highlighting the impact that land use and management can have on the provision of soilbased ecosystem services. Little research has been conducted on the role of soil biota in high input agriculture because natural processes regulating soil structure, nutrient supply, and pests and diseases have been largely replaced by soil tillage, artifi cial fertilizers, and biocides ( Barrios 2007 ). Recent concern about sustaining soil function in intensive agriculture has created a new demand for agricultural practices that are less dependent on external inputs, tighten nutrient cycles, and are productive while enhancing rather than degrading natural capital ( Swift et al. 2004 ). Agroforestry is now broadly defi ned, in scaleneutral terms, as the interaction of agriculture and trees ( Sinclair 2004 ). The fi eld and landscape scales that are a focus here, involve land use practices that combine trees with crops and/or animals in some form of spatial arrangement or temporal sequence that results in signifi cant ecological and economic interactions among trees and agricultural components ( Sinclair 1999 ; Fig. 5.2.1 ). Recent global estimates indicate that nearly half of all agricultural land has >10% tree cover, an area of about 1 billion ha that is home to more than 500 million people ( Zomer et al. 2009 ). The perennial nature of most trees has a profound impact on soil properties, and hence on the abundance, diversity, and function of the soil biota, underpinning soil health.
Changes in Photosynthetic Characteristics between Green-Leaf Poplar Linn. “2025” and Its Bud-Sporting Colored-Leaf Cultivars

Colored-leaf poplar is increasingly popular due to its great ornamental values and application prospects. However, the photosynthetic characteristics of these colored-leaf cultivars have not been well understood. In this study, the photosynthetic differences between green-leaf poplar Populus deltoids Linn. “2025” (L2025) and colored-leaf cultivars ‘Zhonghong poplar’ (ZHP), ‘Quanhong poplar’ (QHP), and ‘Caihong poplar’ (CHP) were investigated on several levels, including chloroplast ultrastructure observation, photosynthetic physiological characteristics, and expression analysis of key genes. The results showed that the photosynthetic performance of ZHP was basically consistent with that of L2025, while the ranges of light energy absorption and efficiency of light energy utilization decreased to different degrees in CHP and QHP. A relatively low water use efficiency and high dark respiration rate were observed in QHP, suggesting a relatively weak environmental adaptability. The differences in chloroplast structure in different colored-leaf poplars were further observed by transmission electron microscopy. The disorganization of thylakoid in CHP was considered an important reason, resulting in a significant decrease in chlorophyll content compared with other poplar cultivars. Interestingly, CHP exhibited extremely high photosynthetic electron transport activity and photochemical efficiency, which were conductive to maintaining its relatively high photosynthetic performance. The actual quantum yield of PSII photochemistry of ZHP was basically the same as that of QHP, while the relatively high photosynthetic performance indexes in ZHP suggested a more optimized photosynthetic apparatus, which was crucial for the improvement of photosynthetic efficiency. The differential expressions of a series of key genes in different colored-leaf poplars provided a reasonable explanation for anthocyanin accumulation and specific photosynthetic processes.
Thermodynamic and elastic properties of pyrope at high pressure and high temperature by first‐principles calculations

Pyrope is an Mg end‐member garnet, which constitutes up to ~15% of the upper mantle. Thermodynamic and thermoelastic properties of garnet at high pressure and high temperature are important for understanding the composition and structure of the Earth. Here we report the first‐principles calculations of vibrational properties, thermodynamic properties, and elasticity of pyrope over a wide pressure and temperature range. The calculated results exhibit good consistency with the available experimental results and provide values up to the pressure and temperature range that are challenging for experiments to achieve and measure. Pyrope is almost isotropic at high pressure. The elastic moduli, especially the shear modulus of pyrope, exhibit nonlinear pressure and temperature dependences. Density and seismic velocities of pyrope along with piclogite, pyrolite, and eclogite are compared with seismic models along the normal upper mantle and the cold subducting lithospheric plate geotherms. Pyrope has the highest density and seismic velocities among the major minerals of the upper mantle along these geotherms. Eclogite with 30% pyrope and 70% clinopyroxene is denser than the surrounding mantle even along the normal upper mantle geotherm and becomes still denser along the cold slab geotherm. Seismic velocities of eclogite with 30% pyrope along the normal upper mantle geotherm are slower than the surrounding mantle but along the cold slab geotherm are faster than the surrounding mantle.
Is eGFR Slope a Novel Predictor of Chronic Complications of Type 2 Diabetes Mellitus? A Systematic Review and Meta-Analysis

Background Diabetic kidney disease affects approximately 40% of patients with type 2 diabetes mellitus (T2DM) and is associated with an increased risk of end-stage kidney disease (ESKD) and cardiovascular (CV) events, as well as increased mortality. Among the indicators of decline in renal function, the eGFR slope is acquiring an increasing clinical interest. The aim of this study was to evaluate, through a systematic review of the literature and meta-analysis of the collected data, the association between the decline of the eGFR slope, chronic complications, and mortality of T2DM patients, in order to understand whether or not the eGFR slope can be defined as a predictive indicator of complications in T2DM. Methods The review and meta-analysis were conducted according to PRISMA guidelines considering published studies on patients with T2DM. A scientific literature search was carried out on PubMed from January 2003 to April 2023 with subsequent selection of scientific papers according to the inclusion criteria. Results Fifteen studies were selected for meta-analysis. Risk analysis as hazard ratio (HR) indicated a significant association between all events considered (all-cause mortality, CV events, ESKD, and microvascular events) for patients with steeper eGFR slope decline than subjects with stable eGFR. Calculated HRs (with 95% CI) were as follows: for all-cause mortality, 2.31 (1.70-3.15); for CV events, 1.73 (1.43-2.08); for ESKD, 1.54 (1.45-1.64); and for microvascular events, 2.07 (1.57-2.73). Overall HR was 1.82 (1.72-1.92). Conclusions An association between rapid eGFR decline and chronic diabetes complications was demonstrated, suggesting that eGFR slope variability significantly impacts the course of T2DM and that eGFR slope should be considered as a predictor for chronic complications in patients with T2DM. According to the obtained results, the therapeutic management of the patient with diabetes should not focus exclusively on glycaemic control, and particular attention should be paid to preserve renal function.
Contribution of APOE Genetic Variants to Dyslipidemia

Background: apo (apolipoprotein) E has crucial role in lipid metabolism. The genetic variation in APOE gene is associated with monogenic disorders and contributes to polygenic hypercholesterolemia and to interindividual variability in cholesterol. APOE rare variants may be involved in the phenotype of genetic hyperlipidemias. Methods: Exon 4 of APOE were sequenced in all consecutive unrelated subjects with primary hyperlipidemia from a Lipid Unit (n=3667) and 822 random subjects from the Aragon Workers Health Study. Binding affinity of VLDL (very low-density lipoprotein) to LDL receptor of pathogenic predicted apoE variants was analyzed in vitro. Lipoprotein particle number, size, and composition were studied by nuclear magnetic resonance. Results: In addition to common polymorphisms giving rise to APOE2 and APOE4, 14 gene variants were found in exon 4 of APOE in 65 subjects. p.(Leu167del) in 8 patients with isolated hypercholesterolemia and in 8 patients with combined hyperlipidemia. Subjects with p.(Arg121Trp), p.(Gly145Asp), p.(Arg154Ser), p.(Arg163Cys), p.(Arg165Trp), and p.(Arg168His) variants met dysbetalipoproteinemia lipid criteria and were confirmed by nuclear magnetic resonance. VLDL affinity for the LDL receptor of p.(Arg163Cys) and p.(Arg165Trp) heterozygous carriers had intermedium affinity between APOE2/2 and APOE3/3. p.(Gly145Asp) and p.(Pro220Leu) variants had higher affinity than APOE3/3. Conclusions: APOE genetic variation contributes to the development of combined hyperlipidemia, usually dysbetalipoproteinemia, and familial hypercholesterolemia. The lipid phenotype in heterozygous for dysbetalipoproteinemia-associated mutations is milder than the homozygous APOE2/2-associated phenotype. Subjects with dysbetalipoproteinemia and absence of APOE2/2 are good candidates for the study of pathogenic variants in APOE. However, more investigation is required to elucidate the significance of rarer variants of apoE.
The Effect of Dexlansoprazole on Gastroesophageal Reflux Disease: A Systematic Review and Meta-Analysis

This systematic review and meta-analysis evaluated the efficacy of dexlansoprazole (a proton pump inhibitor—PPI) in resolving heartburn, reflux, and other symptoms and complications resulting from gastroesophageal reflux disease (GERD). The study followed PRISMA 2020 and was registered in PROSPERO (CRD42020206513). The search strategy used MeSH and free terms appropriately adapted for each database. Only randomized clinical trials (RCTs) were included. The Cochrane tool (RoB 2.0) was used to assess the risk of bias, and the certainty of evidence was rated using GRADE. Ten RCTs were included. Dexlansoprazole outperformed the placebo and other PPIs in the resolution of heartburn and reflux symptoms in patients with GERD, with benefits during and after treatment, especially in those with moderate and severe symptoms. The meta-analyses indicated that dexlansoprazole at doses of 30 and 60 mg had more 24 h heartburn-free days and nights compared to the placebo medications; no difference was reported between dexlansoprazole at doses of 30 and 60 mg in heartburn-free nights. A low bias risk and a moderate certainty of evidence were observed. This review confirms the therapeutic effect of dexlansoprazole (placebo-controlled) and its improvements in GERD symptoms compared to another PPI. However, the interpretation of the results should be carried out cautiously due to the small number of included studies and other reported limitations.