Miracle-dz/UniFAR-FTUs huggingface dataset:
Clinical and Pathological Predictors of Death for Adrenocortical Carcinoma

Abstract Adrenocortical carcinoma (ACC) is a rare and lethal disease with a poor prognosis. This study aims to share our 41-year experience as a referral center, focusing on identifying risk factors associated with ACC mortality. Our retrospective analysis included a cohort of 150 adult patients with ACC in all stage categories, treated between 1981 and 2022. Tumor hormonal hypersecretion was observed in 78.6% of the patients, and the median age of diagnosis was 40 years. The majority presented as European Network for the Study of Adrenal Tumors (ENSAT) III or IV (22.9% and 31.2%, respectively), and the overall mortality rate was 54.6%. Independent predictors of death were elevated secretion of cortisol (HR = 2.0), androstenedione (HR = 2.2), estradiol (HR = 2.8), 17-OH progesterone (HR = 2.0), and 11-deoxycortisol (HR = 5.1), higher Weiss (HR = 4.3), modified Weiss (HR = 4.4), and Helsinki scores (HR = 12.0), advanced ENSAT stage (HR = 27.1), larger tumor size (HR = 2.7), higher Ki-67 percentage (HR = 2.3), and incomplete surgical resection (HR = 2.5). Mitosis greater than 5/50 high-power field (HR = 5.6), atypical mitosis (HR = 2.3), confluent necrosis (HR = 15.4), venous invasion (HR = 2.8), and capsular invasion (HR = 2.4) were also identified as independent predictors of death. Knowing the risk factors for ACC's mortality may help determine the best treatment option.
Dukungan Keluarga Dengan Kualitas Hidup Pada Pasien Kanker Payudara Yang Menjalani Kemoterapi

Background:Cancer is one of the main causes of death in the world. The incidence of breast cancer is the second highest in the world. The many impacts ofchemotherapy treatment that is undertaken, will become a long-term problem that will affect the patient's qualit y of life. Unfavorable psychological conditions due to chemotherapy make cancer patients need support from the closest people, the family is the patient's closest person who will provide comfort and peace. Objective:To analyze the effect of family support on the quality of life of breast cancer patients undergoing chemotherapy Methods: The method of this study is correlated with a cross-sectional approach. with 86 samples using a non-probability sampling technique with consecutive sampling and using a measuring instrument used on variables using a questionnaire. Results:The results of the analysis using the Spearman Rank Tests ? 0.05 obtained a p-value (0.00 <? (0.05). Conclusion:There is a relationship between family support and quality of life in breast cancer patients undergoing chemotherapy at Level III Hospital Baladhika Husada Jember. Family support is one of the factors that have a positive contribution to the quality of life of cancer patients. The family support provided can be in the form of attention or an active role in the treatment and therapy programs being undertaken by breast cancer patients. Involvement of family members in motivating to maintain the condition and perform chemotherapy
Cold sintering process of hydroxyapatite derived from natural bone and co-precipitation method: a comparative study

This study uses a novel sintering technique at very low temperatures (below 300°C) named the Cold Sintering Process to produce highly dense Hydroxyapatite (HA) samples. Nano hydroxyapatite was prepared using two different methods: Synthesis by chemical precipitation method (HA 1 ) and natural source from Boven bone (HA 2 ). The samples are characterized using scanning electron microscope (SEM), X-ray energy dispersive spectrometry (EDS), X-ray diffractogram (XRD), transition electron microscope (TEM), Fourier transform infrared spectrometry (FTIR) and Nuclear magnetic resonance spectroscopy (NMR). Also, physical and mechanical properties measurements were detected, including density and hardness. The results indicated that cold sintering could result in Hydroxyapatite with high densification, high purity, and high stability without thermal decomposition compared with traditional sintering. The relative density and hardness for HA 1 are 99% and 502HV, respectively. The relative density and hardness for HA 2 are 69% and 350HV, respectively. It can be observed that the HA 1 sample has higher densification than HA 2 due to the presence of organic matter in natural Hydroxyapatite HA 2 . This organic material will be removed during the cold sintering process, leaving pores that lead to low densification of HA 2 samples. It can be concluded that the synthesis hydroxyapatite (HA 1 ) can be easily sintered by a cold sintering process compared with natural one(HA 2 ).
Effect of hyperbaric chamber on saturation and heart frequency

Introduction: (1) Background: The use of oxygen under pressure greater than atmospheric represents progress that can be measured in terms of importance with the introduction of blood transfusion and antibiotics in therapy. The aim of the research was to determine the impact of using a hyperbaric chamber (HC) on muscle, arterial saturation and heart rate. ; (2) Methods: Twelve respondents who engaged in recreational exercise. HC Macy Pan O2 801 was used for oxygen delivery. Muscle saturation was assessed with the IDIAG Moxy device. Arterial saturation was monitored with an Omron OM-35 device, and intraventricular heart rate with a Polar FT2 device. All parameters were monitored before and after HC treatment for 50 min. and constant pressure of 2.5 ATA. ; (3) Results: There was a significant increase in saturation in the pectoralis, (+8.99%) p=. 038, hamstring (+8.62%) p=. 042. In capillary saturation (+1.42%) p=. 008. Heart rate was reduced on average by about 8.5 beats p= . 003. In the region of the latissimus do not record a statistically significant change in oxygen (+6.64%) p=060, however, numerical differences were determined. ; (4) Conclusions: HC is an effective means of achieving positive physiological effects. It needs to be determined whether a higher ATA or duration of treatment gives better effects.
. The in-Effects of depleting ionic strength on 31 P nuclear magnetic resonance spectra of micellar casein during membrane separation and diafiltration of skim milk

Membrane separation processes used in the concentration and isolation of micellar casein-based milk proteins from skim milk rely on extensive permeation of its soluble serum constituents, especially lactose and minerals. Whereas extensive literature exists on how these processes influence the gross composition of milk proteins, we have little understanding of the effects of such ionic depletion on the core structural unit of micellar casein [i.e., the casein phosphate nanocluster (CPN)]. The 31 P nuclear magnetic resonance (NMR) is an analytical technique that is capable of identifying soluble and organic forms of phosphate in milk. Thus, our objective was to investigate changes to the 31 P NMR spectra of skim milk during microfiltration (MF) and diafiltration (DF) by tracking movements in different species of phosphate. In particular, we examined the peak at 1.11 ppm corresponding to inorganic phosphate in the serum, as well as the low-intensity broad signal between 1.5 and 3.0 ppm attributed to casein-associated phosphate in the retentate. The MF concentration and DF using water caused a shift in the relevant 31 P NMR peak that could be minimized if orthophosphate was added to the DF water. However, this did not resolve the simultaneous change in reten-tate pH and increased solubilization of micellar casein protein. The addition of calcium in combination with orthophosphate prevented micellar casein solubilization and simultaneously contributed to preservation of the CPN structure, except for overcorrection of retentate pH in the acidic direction. A more complex DF solu-tion, involving a combination of phosphate, calcium, and citrate, succeeded in both CPN and micellar casein structure preservation while maintaining retentate pH in the region of the original milk pH. The combination of 31 P NMR as an analytical technique and experimental probe during MF/DF processes provided useful insights into changes occurring to CPN while retaining the micellar state of casein
Entrepreneurial Knowledge, Self-Efficacy, and The Impact of The Environment on The Entrepreneurial Interests in Electronic Engineering Department Students

The purpose of this study was to demonstrate the potential impact of entrepreneurial knowledge, self-efficacy, and environmental factors on entrepreneurial interest. This study uses an explanatory research approach. The population is students of Universitas Negeri Padang, Department of Electronics Engineering, using a purposive sampling technique. A sample of 80 respondents was determined using accidental sampling technique. Data was collected using questionnaires and tests. Then the method used is purposive sampling and data collection using accidental sampling. The analytical tool used is multiple linear regression analysis. The results of the study show that entrepreneurship education, entrepreneurial self-efficacy and environmental factors influence interest in entrepreneurship
Employee Benefits and Firm Value of Listed Nigerian Consumer Goods Manufacturing Firms

The practice of rejigging the firm value of manufacturing companies by considering employee benefits after the adverse effect of the global lockdown of COVID-19 formed the crux of this study. The study investigated the influence of employee benefits on the firm value of listed manufacturing firms in Nigeria. Specifically, it examined the influence of incentives, health, safety, life insurance, and retirement benefits on firm value. The study adopted ex-post facto and longitudinal research designs. 22 consumer goods manufacturing firms listed on the Nigeria Exchange (NGX) formed the study population as of December 31, 2021. A census sampling technique was used, automatically making the 22 listed firms the study’s sample size. Data were obtained from published annual reports of the firms covering ten years, starting from 2012 to 2021 financial year. The data were analysed using descriptive statistics and panel regression. Findings revealed that incentives, health, safety, life insurance, and retirement benefits negatively and significantly affect Tobin’s list of consumer goods manufacturing firms in Nigeria. The study concluded that re-strategising incentives, health, safety, life insurance, and retirement benefits as policies would make firms perform better and increase their value. The study recommends that employee benefit policy and system be reviewed to reduce cost, staff population be cut down, and the firms adopt more non-monetary benefits to improve their wealth.
Arthroscopy of septic ankle and subtalar joints: A case

Infection of the ankle and subtalar joints is a serious and potentially debilitating condition. ​ Of the few reported cases, results have varied. Traditionally open procedures have been performed, some of which even led to amputation. In the case presented, the authors demonstrate a successful result utilizing arthroscopic techniques in combination with intravenous antibiotic therapy. At two-year follow-up the patient has remained infection free.
Clinics in Oncology

Non-Small Cell Lung Cancer (NSCLC) is a common type of lung cancer, and Epidermal Growth Factor Receptor (EGFR) mutation is a key subtype. NSCLC patients with EGFR mutations generally show better responses to targeted therapy; however, brain metastasis remains a clinical challenge in this patient population. This review aims to delve into the correlation, diagnostic methods, and treatment strategies of EGFR mutations and brain metastasis in NSCLC patients. Firstly, we discuss the correlation between EGFR mutations and the incidence of brain metastasis as well as the survival time of NSCLC patients. We analyze the differences that EGFR mutations
Detection of mini-UAVs in the presence of strong topographic relief: a multisensor perspective

Based on the steadily growing use of mini-UAVs for numerous civilian and military applications, mini-UAVs have been recognized as an increasing potential threat. Therefore, counter-UAV solutions addressing the peculiarities of this class of UAVs have recently received a significant amount of attention. Reliable detection, localization, identification and tracking represents a fundamental prerequisite for such counter-UAV systems. In this paper, we focus on the assessment of different sensor technologies and their ability to detect mini-UAVs in a representative rural Swiss environment. We conducted a field trial in August 2015, using different, primarily short range, experimental sensor systems from armasuisse and selected research partners. After an introduction into the challenges for UAV detection in regions with strong topographic relief, we will introduce the experimental setup and describe the key results from this joint experiment.
Large-scale tungsten-tin mineralization in the Nanling region,South China:Metallogenic ages and corresponding geodynamic processes.

The Nanling region,located in the central part of South China,is the most important W-Sn metallogenic province in China and even over the world.Based on the latest highly precise radiometric dating of the ores and related granites and new progress in the study of geodynamic processes we propose that large-scale W-Sn mineralization occurred in the Nanling region in the Mid-Late Jurassic(165 to 150 Ma)and that its corresponding tectonic setting could be a back-arc region of the continental margin.When the Paleo-Pacific plate was subducted beneath the Eurasian continent,a number of paralleling NE-trending extensional belts developed in a back-arc region where the mantle-crust interaction was strong.The intersection sites between these extensional belts and long-lived previous E-W-trending faults were the central areas of magmatism and mineralization,and the largest W-Sn-Mo-Bi-Be mineralization clusters in southern Hunan is located in the intersection site between the Shihang NE-trending fault belt and the E-W-trending deep fault in the middle ridge zone of the Nanling region.In the Mid-Late Cretaceous,because the Paleo-Pacific plate or Izalagi plate strike- shift to NNE-direction the Eurasian continent started to extension.In this geodynamic setting,the large-scale volcanic eruption mainly took place east of the Wuyi Mountains whereas range-basin tectonics appeared extensively in South China including the Nanling region, NNE-trending Cretaceous red bed-volcanic basins alternate with uplifts represented by granite,and some granite stocks emplaced at 130～90 Ma and their related tin mineralization can be found in some basins.For instance,the Yanbei and Taoxiba in Jinagxi province, Yinyan in Guangdong province and the Jiepailing in the Hunan province occurred in this period as porphyry or porphyry-skarn ores.
Development of Practicum Assessment Rubric Assisted by Google Spreadsheet in Basics Electronics Material

The implementation of practicum assessment rubrics in the Physics Education Laboratory of UIN Alauddin Makassar has fallen short of its full potential. Thus, it is critical to develop a standardized rubric. The practicum assessment rubric is utilized to assess the proficiency of students during their practicum. This research aims to (1) describe the procedure for developing a practicum implementation assessment rubric for Basic Electronics courses with the assistance of the Google Spreadsheet application; and (2) describe the quality of the practicum implementation assessment rubric based on validity and practicality for Basic Electronics courses with the assistance of the Google Spreadsheet application. The utilized development model is Tessmer's formative research model, which comprises two stages: preliminary and formative evaluation. The formative evaluation stage incorporates self-evaluation, prototyping (including expert reviews, one-on-one, and small group), and a field test. This research was conducted at the Physics Education Laboratory of UIN Alauddin Makassar. The research subject comprised two individuals: the main subject and the trial test subject. The main subject comprised two individuals who subsequently formed the product validator team. The trial test subject comprised seven individuals who were employed as assistants for the Electronics practicum in 2022/23. The research results indicated that the validity of the developed product is deemed valid with the validity value of 1. Based on the practicality analysis results, which indicated that 29% of users provided practical responses and 71% provided very practical responses regarding the developed products, it can be inferred that the developed assessment rubric satisfied the practicality criteria. The results of this study suggest that the developed assessment rubric facilitates the assessment administered by the practicum assistants. Additionally, the developed assessment rubric is applicable to all practicum titles pertaining to Basic Electronics.
Graphical methods of river profile analysis to unravel drainage area change, uplift and erodibility contrasts in the Central Range of Taiwan

To reveal river channel steepness patterns and variance in settings with significant variation in rock uplift rate, rock erodibility and moving water divides, we present a series of graphical methods to interpret channel profiles. To complement Cartesian χ plots, longitudinal profiles and mapping methods, we introduce a new method based on a radial coordinate system. We map each basin onto polar coordinates in which the radial dimension is χ and the azimuthal coordinate, ϕ, is calculated with an increment (Δϕ) scaled to the distance to neighboring channel heads. The elevation is contoured on this mapping. Average channel steepness is estimated by fitting a conical surface to the elevation. The graph simplifies the comparison of χ and elevation between channels that share a divide, and helps identify spatial changes in drainage area and patterns of erodibility.
Surrogate safety evaluation of curve sections on an interurban highway under heterogeneous traffic conditions in India

Road traffic safety is a global concern. Conventionally, road safety evaluation is carried out by analyzing historical crash data, which is a reactive approach to safety analysis. The safety analyst has to wait for sufficient time to accumulate crash data before taking up any safety analysis as a sample of substantial crashes is required for analysis. But in safety analysis with a proactive approach no crash data is required, which is replaced with surrogate “conflicts”, which can be obtained from the new techniques of traffic conflict technique and surrogate safety parameters. Other approaches can be applied in traffic safety evaluation in anticipation of the crash occurrence. The advent of traffic conflict techniques, i.e., use of traffic conflicts in place of crashes and microsimulation methods like modeling of the traffic flow and pattern in traffic streams on a road network, started to apply as a method of analyzing microscopic simulation models and traffic conflict techniques to determine the safety issues in traffic systems and correlate them to the probable incidences of collisions. In this regard, surrogate safety parameters have been used to determine the level of safety on the typical curve sections of an interurban highway namely, Faridabad-Gurgaon four-lane divided highway in Haryana, India. This is accomplished by the use of vehicle trajectory data extracted through microscopic simulation in Verkher in Staedten Simulation (VISSIM) and analysis in Surrogate Safety Assessment Model (SSAM) for the above-referred corridor. Further, efforts have been made to present the intensity of traffic conflicts happening at the curved sections. The surrogate safety measures time to collision (TTC), deceleration rate (DR), and change in velocity (ΔV), as well as conflicting vehicle speed (Max S), are obtained by analysis from the SSAM model for all the curve sections and are validated using the reported crash data on the curve sections of the candidate corridor for 3 years. With the help of statistical elaboration, the critical threshold for TTC with the heterogeneous traffic movement is found 1.6 s, meaning any conflict occurring less than this time would invariably lead to a fatal crash. Similarly, the critical deceleration rate is observed as 0.569 m/s2, implying that any conflict with more than this value may lead to a fatal crash. Further, the DeltaV values deduced for the study corridor on interurban curve sections catering to heterogeneous traffic movement is 4.1 m/s. Again, any conflict more than this value can turn into a potential crash.
Mediterranean Land Use and Land Cover Classification Assessment Using High Spatial Resolution Data

Landscape fragmentation is noticeably practiced in Mediterranean regions and imposes substantial complications in several satellite image classification methods. To some extent, high spatial resolution data were able to overcome such complications. For better classification performances in Land Use Land Cover (LULC) mapping, the current research adopts different classification methods comparison for LULC mapping using Sentinel-2 satellite as a source of high spatial resolution. Both of pixel-based and an object-based classification algorithms were assessed; the pixel-based approach employs Maximum Likelihood (ML), Artificial Neural Network (ANN) algorithms, Support Vector Machine (SVM), and, the object-based classification uses the Nearest Neighbour (NN) classifier. Stratified Masking Process (SMP) that integrates a ranking process within the classes based on spectral fluctuation of the sum of the training and testing sites was implemented. An analysis of the overall and individual accuracy of the classification results of all four methods reveals that the SVM classifier was the most efficient overall by distinguishing most of the classes with the highest accuracy. NN succeeded to deal with artificial surface classes in general while agriculture area classes, and forest and semi-natural area classes were segregated successfully with SVM. Furthermore, a comparative analysis indicates that the conventional classification method yielded better accuracy results than the SMP method overall with both classifiers used, ML and SVM.
Sleep bruxism and perceived stress: assessment using salivary cortisol levels, a biomarker of stress

Sleep bruxism (SB) corresponds to physiologically based manducatory muscle reactions, with no identifiable neuropathic cause, in relation to anxiety disorders, respiratory disorders or behavioral "tocs". The aim of this study was to assess the relationship between SB and perceived stress by measuring salivary cortisol levels. The study included 61 consenting adult participants: 31 for the study group (bruxers) and 30 for the control group (no bruxers). The diagnosis of BS was made using a standard bruxism assessment questionnaire defined by the American Academy of Sleep Medicine (AASM). The preliminary diagnosis was confirmed by clinical assessment according to AASM criteria. The BRUXi index, a tool proposed by Orthlieb, was used to determine the intensity of bruxism. Perceived stress was measured using the Perceived Stress Scale questionnaire. Unstimulated whole saliva was collected and morning salivary cortisol levels were determined by ELISA. Non-parametric statistical methods were used to analyze the data. The bruxers (study group) had significantly high levels of mean salivary cortisol (12.3±4.2 ng/mL or 34.5±14.6 nmol/L) than the non-bruxers (control group) (5.3±1.2 ng/mL or 14.5±4.6 nmol/L) (p<0.001). The elevated salivary cortisol level was positively associated with perceived stress and SB (p<0.0001) in the study group. These results suggest that bruxing activity is associated with higher levels of perceived psychological stress and salivary cortisol. Despite the absence of polysomnographic recording for the diagnosis of SB, a positive correlation between SB and salivary cortisol levels was observed in bruxers.