Miracle-dz/UniFAR-FTUs huggingface dataset:
Coping With Plenitude: A Computational Approach to Selecting the Right Algorithm

Sociologists increasingly face choices among competing algorithms that represent reasonable approaches to the same task, with little guidance in choosing among them. We develop a strategy that uses simulated data to identify the conditions under which different methods perform well and applies what is learned from the simulations to predict which method will perform best on never-before-seen empirical data sets. We apply this strategy to a class of methods that group respondents to attitude surveys according to whether they share construals of a given domain. This allows us to identify the relative strengths and weaknesses of the methods we consider, including relational class analysis, correlational class analysis, and eight other such variants. Results support the “no free lunch” view that researchers should abandon the quest for one best algorithm in favor of matching algorithms to kinds of data for which each is most appropriate and provide direction on how to do so.
Sex Differences in Age-Related Physical Changes among Community-Dwelling Adults

The prevalence of physical functioning limitations is positively correlated with age in both men and women. However, whether the appearance of deterioration differs depending on physical function and sex remains unclear. This study aimed to clarify the modes of age-related changes in physical function and sex differences in middle-aged and older adults. This study comprised 124 (46 men and 78 women) healthy adults aged 30 years or older and examined gender differences in physical function. The results of this study showed that one-leg standing time had the highest rate of age-related decline in both men and women, followed by knee extension strength, skeletal muscle mass, the 5 m walking test, and the timed up and go test. The sex-specific points showed a high rate of decline in trunk forward bending in men and a high rate of decline in forced expiratory volume (1 s) and gradual rate of decline in the bone area ratio in women. After middle age, it is desirable to start monitoring and training balance, muscle function, and walking. Men require early intervention for flexibility, and women require early intervention for respiratory function and continued intervention for bone mineral density.
Cell and Cell-Free Therapies to Counteract Human Premature and Physiological Aging: MSCs Come to Light

The progressive loss of the regenerative potential of tissues is one of the most obvious consequences of aging, driven by altered intercellular communication, cell senescence and niche-specific stem cell exhaustion, among other drivers. Mesenchymal tissues, such as bone, cartilage and fat, which originate from mesenchymal stem cell (MSC) differentiation, are especially affected by aging. Senescent MSCs show limited proliferative capacity and impairment in key defining features: their multipotent differentiation and secretory abilities, leading to diminished function and deleterious consequences for tissue homeostasis. In the past few years, several interventions to improve human healthspan by counteracting the cellular and molecular consequences of aging have moved closer to the clinic. Taking into account the MSC exhaustion occurring in aging, advanced therapies based on the potential use of young allogeneic MSCs and derivatives, such as extracellular vesicles (EVs), are gaining attention. Based on encouraging pre-clinical and clinical data, this review assesses the strong potential of MSC-based (cell and cell-free) therapies to counteract age-related consequences in both physiological and premature aging scenarios. We also discuss the mechanisms of action of these therapies and the possibility of enhancing their clinical potential by exposing MSCs to niche-relevant signals.
Seismic Structure of the St. Paul Fracture Zone and Late Cretaceous to Mid Eocene Oceanic Crust in the Equatorial Atlantic Ocean Near 18°W

Plate tectonics characterize transform faults as conservative plate boundaries where the lithosphere is neither created nor destroyed. In the Atlantic, both transform faults and their inactive traces, fracture zones, are interpreted to be structurally heterogeneous, representing thin, intensely fractured, and hydrothermally altered basaltic crust overlying serpentinized mantle. This view, however, has recently been challenged. Instead, transform zone crust might be magmatically augmented at ridge‐transform intersections before becoming a fracture zone. Here, we present constraints on the structure of oceanic crust from seismic refraction and wide‐angle data obtained along and across the St. Paul fracture zone near 18°W in the equatorial Atlantic Ocean. Most notably, both crust along the fracture zone and away from it shows an almost uniform thickness of 5–6 km, closely resembling normal oceanic crust. Further, a well‐defined upper mantle refraction branch supports a normal mantle velocity of 8 km/s along the fracture zone valley. Therefore, the St. Paul fracture zone reflects magmatically accreted crust instead of the anomalous hydrated lithosphere. Little variation in crustal thickness and velocity structure along a 200 km long section across the fracture zone suggests that distance to a transform fault had negligible impact on crustal accretion. Alternatively, it could also indicate that a second phase of magmatic accretion at the proximal ridge‐transform intersection overprinted features of starved magma supply occurring along the St. Paul transform fault.
Accuracy in detecting major depressive episodes in older adults using the Swedish versions of the GDS-15 and PHQ-9

Objectives The purpose of this study was to evaluate the diagnostic accuracy at different cut-off values for the Swedish versions of the 15-item Geriatric Depression Scale (GDS-15) and Patient Health Questionnaire (PHQ-9) compared with a structured clinical psychiatric interview in older adults. Methods Community-dwelling participants (N = 113) aged 65 years or older completed the Swedish versions of the GDS-15 and PHQ-9 and were then interviewed using the Mini International Neuropsychiatric Interview (MINI) to establish the presence or absence of current major depressive episodes (MDEs). Areas under the curve (AUC) were calculated for each scale, as well as the sensitivity, specificity, and Youden’s index for different cut-off values. Results Seventeen participants met the criteria for MDEs. The AUC was 0.97 for the GDS-15 and 0.95 for the PHQ-9. A cut-off of ≥6 on the GDS-15 yielded a sensitivity of 94%, a specificity of 88%, and a Youden’s index of 0.82. A cut-off of ≥5 on the PHQ-9 yielded a sensitivity of 100%, a specificity of 81%, and a Youden’s index of 0.81. The proposed cut-off of ≥10 on the PHQ-9 produced excellent specificity of 95% but a lower sensitivity of 71%. Conclusions This study indicates that the Swedish versions of the GDS-15 and PHQ-9 have comparable accuracy as screening instruments for older adults with MDEs. However, the proposed cut-off of 10 on the PHQ-9 might be too high when applied to older individuals in Sweden, and further investigations in larger samples in different healthcare settings are warranted.
Root Cause Analysis Using the Prevention and Recovery Information System for Monitoring and Analysis Method in Healthcare Facilities: A Systematic Literature Review

Objectives Unintended events (UEs) are prevalent in healthcare facilities, and learning from them is key to improve patient safety. The Prevention and Recovery Information System for Monitoring and Analysis (PRISMA)-method is a root cause analysis method used in healthcare facilities. The aims of this systematic review are to map the use of the PRISMA-method in healthcare facilities worldwide, to assess the insights that the PRISMA-method offers, and to propose recommendations to increase its usability in healthcare facilities. Methods PubMed, EMBASE.com, CINAHL, and The Cochrane Library were systematically searched from inception to February 26, 2020. Studies were included if the PRISMA-method for analyzing UEs was applied in healthcare facilities. A quality appraisal was performed, and relevant data based on an appraisal checklist were extracted. Results The search provided 2773 references, of which 25 articles reporting 10,816 UEs met our inclusion criteria. The most frequently identified root causes were human-related, followed by organizational factors. Most studies took place in the Netherlands (n = 20), and the sample size ranged from 1 to 2028 UEs. The study setting and collected data used for PRISMA varied widely. The PRISMA-method performed by multiple persons resulted in more root causes per event. Conclusions To better understand UEs in healthcare facilities and formulate optimal countermeasures, our recommendations to further improve the PRISMA-method mainly focus on combining information from patient files and reports with interviews, including multiple PRISMA-trained researchers in an analysis, and modify the Eindhoven Classification Model if needed.
Treatment of oral chronic graft-versus-host disease: a retrospective cohort study

ABSTRACT Objective The aim of this study was to evaluate patients with complete response of oral chronic graft-versus-host disease to immunosuppressive treatment. Methods A total of 29 patients submitted to allogeneic hematopoietic stem cell transplantation, with oral chronic graft-versus-host disease, were enrolled in this retrospective study, from September 2012 to February 2018. Patients were treated with combined topical dexamethasone solution and topical tacrolimus ointment, combined topical dexamethasone and topical tacrolimus, systemic immunosuppressive medication, and topical dexamethasone only. Results The mean time of complete response of lichenoid lesions, erythema, and ulcers using dexamethasone and systemic immunosuppressive medication was of 105, 42 and 42 days, respectively (p=0.013). When we associated dexamethasone, tacrolimus and systemic immunosuppressive medication, the mean time of complete response of lichenoid lesions, erythema and ulcers was of 91,84 and 77 days (p=0.011). When dexamethasone was used alone, the mean time of complete response of lichenoid lesions, erythema and ulcers was 182, 140, 21 days, respectively (p=0.042). Conclusion Our study shows that lichenoid lesions require more time to heal. Notably, lichenoid lesions tend to respond better to dexamethasone combined with tacrolimus and systemic immunosuppressive medication, whereas erythema and ulcers respond better to dexamethasone combined with systemic immunosuppressive medication and dexamethasone only, respectively.
Influence of Hydrogen Peroxide and Nanofertilizer on Rusts Development and Wheat Productivity

Wheat (Triticum aestivum L.) is the most strategic cereal crop allover the world and Egypt. Egypt faces food shortage problems because of increment of population. Therefore, Egypt is considered one of the biggest importers of wheat all over the world. Great efforts are continually driven for increasing its productivity by means of horizontal and/or vertical planting to reduce hiatus between production and consumption.
Genomic Risk Factors for Cervical Cancer

Simple Summary Cervical cancer is the fourth leading cause of cancer-related deaths in females worldwide. Despite an active immunisation strategy in many countries, high-risk human papillomavirus infection and environmental factors may result in cervical cancer progression. Genetic factors contributing to host–pathogen interactions are incompletely understood and remain largely unknown, apart from the variants at the human leukocyte antigen (HLA) locus on 6p21.3, which replicates across populations. Novel cervical cancer susceptibility loci from recent large biobank-based genome-wide association studies and meta-analyses are likely to be more robust as compared to previous candidate gene based studies. In this review, we summarize findings from recent genome-wide association studies on cervical cancer and propose variants that may be universal susceptibility loci. Abstract Cervical cancer is the fourth common cancer amongst women worldwide. Infection by high-risk human papilloma virus is necessary in most cases, but not sufficient to develop invasive cervical cancer. Despite a predicted genetic heritability in the range of other gynaecological cancers, only few genomic susceptibility loci have been identified thus far. Various case-control association studies have found corroborative evidence for several independent risk variants at the 6p21.3 locus (HLA), while many reports of associations with variants outside the HLA region remain to be validated in other cohorts. Here, we review cervical cancer susceptibility variants arising from recent genome-wide association studies and meta-analysis in large cohorts and propose 2q14 (PAX8), 17q12 (GSDMB), and 5p15.33 (CLPTM1L) as consistently replicated non-HLA cervical cancer susceptibility loci. We further discuss the available evidence for these loci, knowledge gaps, future perspectives, and the potential impact of these findings on precision medicine strategies to combat cervical cancer.
Marketing Schools of Thought and Their Present Day Relevance

The present article is the compendium of the 12 schools of thought (namely, ‘commodity’, ‘functional’, ‘regional’, ‘institutional’, ‘functionalist’, ‘managerial’, ‘buyer behaviour’, ‘activist’, ‘macro-marketing’, ‘organizational dynamics’, ‘systems’ and ‘social exchange’) in the marketing discipline since its inception in the early 1900s. These 12 schools of thought belong to the four quadrants on the two dimensions, namely ‘Interactive/Non-interactive’ perspective and ‘Economic/Non-economic’ perspective. The similarities, dissimilarities and focal points of these schools of thought have been briefly discussed. The article highlights, how the focal points across the schools of marketing thought have been continuously changing. The major contributions under these schools have also been discussed. Further, the article provided a general overview and criticism of these schools of the marketing discipline. The article further discusses the five controversies around the history of marketing, which are about the dominant perspective in marketing, the relationship between marketing and society, homogeneity of the internal subdivisions of marketing, the debate about marketing as science or arts and the creation of the general theory of marketing. The article also discusses the important issue of plugging the gap between the academic and managerial perspectives of the marketing theories.
The frequency of hyponatremia during the course of small cell lung cancer and its effect on prognosis

BACKGROUND AND AIM: Small‐cell lung cancer (SCLC) is fast‐growing disease with high mortality and prognosis is worse when hyponatremia develops. In our study, we aimed to determine the frequency of hyponatremia in SCLC and the relationship with the prognosis. MATERIALS AND METHODS: Patients diagnosed with SCLC between 2012 and 2017 were retrospectively screened. Stages, hyponatremia levels, and survival times were recorded. RESULTS: A total of 466 patients diagnosed with SCLC, 423 (90.8%) of whom were male were included in the study. The average age was 67 ± 10 years. About 126 (27%) of the patients were hyponatremic and 340 (73%) were normonatremic. Hypertonic saline treatment was performed in 52 (41.3%) patients. In total, hyponatremia improved in 49.2% (n = 62). While the expected survival means were 12.6 months in those with improved hyponatremia, 5.0 months in those with not improved, and 12.3 months in the normonatremic group. Survival in the group of whom hyponatremia could not be corrected was found to be statistically different (P < 0.05). CONCLUSION: The improvement of hyponatremia was found to be a positive independent factor on the survival of SCLC.
Ecosystem stability at the landscape scale is primarily associated with climatic history

1. There is an increasing interest in landscape-scale perspectives of ecosystem functioning to inform policy and conservation decisions. However, we need a better understanding of the stability of ecosystem functioning (e.g. plant productivity) at the landscape scale to inform policy around topics such as global food security. 2. We investigate the role of the ecological and environmental context on landscape-scale stability of plant productivity in agricultural pasture using remotely sensed enhanced vegetation index data. We determine whether four measures of stability (variability, magnitude of extreme anomalies, recovery
'Patterns and causes of marsupial paths in subalpine Tasmania

Animal paths can improve connectivity of species, alter vegetation growth, reduce fuel loads and further our knowledge of the behavioural ecology of mammals. Path patterning and the motivations for path creation are not well understood. The present study tested the hypotheses that animals form paths: (i) to efficiently move between palatable patches; (ii) for access to water; (iii) for access to shelter and (iv) to avoid predators. We used high-definition aerial online imagery to map paths in five treeless subalpine environments in Tasmania. Surveys of vegetation and scat counts were conducted at each site. We found that locality influenced wallaby scat density and that macropods and wombats created direct paths to move between areas of palatable vegetation, shelter and water. There was some weak indication of predator avoidance in some of the patterning. However, shelter from cold, strong southwesterly winds is a feasible alternative motivation for the patterns.
News About Terrorism and Attitudes Toward Countries: The Role of Mortality Salience and Intergroup Threat

Background Media reports on armed fights or terror attacks introduce reminders of death into people’s daily lives. When people feel non-specific threats (mortality salience) or specific threats (intergroup threats), they may demonstrate unfavorable attitudes toward national outgroups. The issue is mostly analyzed today in line with Terror Management Theory and Intergroup Threat Theory. Objective To examine such threats in the Russian context, and the impact of mortality salience (MS) on attitudes toward national outgroups that induced different levels of perceived intergroup threat. Design In two studies, participants watched films and completed questionnaires about social distance, social thermometer, and trust toward “more or less threatening” countries. In Study 1, 120 Russian students were assigned to six groups via experimental design: 3 (MS: terrorist attacks in Europe, terrorist attacks in Russia, or a control group watching a video about dental treatment) x 2 (country: Ukraine and Belarus). In Study 2, 122 participants were similarly divided into six groups, evaluating attitudes toward the USA and China. Results Study 1 showed that MS mostly increased unfavorable attitudes toward a country perceived as more threatening (Ukraine) than toward one perceived as less threatening (Belarus). Study 2 indicated the same effect on attitudes toward both more (the USA) and less (China) threatening outgroups. Conclusion The results identified contradictory tendencies in MS effect, in line with Terror Management Theory and Intergroup Threat Theory. The findings could be used in improving relationships from an international perspective.
The Person’s Care Requires a Sex and Gender Approach

There is an urgent need to optimize pharmacology therapy with a consideration of high interindividual variability and economic costs. A sex–gender approach (which considers men, women, and people of diverse gender identities) and the assessment of differences in sex and gender promote global health, avoiding systematic errors that generate results with low validity. Care for people should consider the single individual and his or her past and present life experiences, as well as his or her relationship with care providers. Therefore, intersectoral and interdisciplinary studies are urgently required. It is desirable to create teams made up of men and women to meet the needs of both. Finally, it is also necessary to build an alliance among regulatory and ethic authorities, statistics, informatics, the healthcare system and providers, researchers, the pharmaceutical and diagnostic industries, decision makers, and patients to overcome the gender gap in medicine and to take real care of a person in an appropriate manner.
Exploring Student Metacognitive Failures Based on Red Flag in Mathematic Problem Solving: A Case Study in Mathematic Education Program

The purpose of this article is to explore student’s metacognitive failure based on red flag in mathematics problem solving. Red flag is a term that indicates the metacognitive failure was occurred, which is characterized by (1) there is an error detection, (2) no progress at processing step of activities, and (3) there is an ambiguity in the final answer, that can be appeared in metacognitive activities. There are three metacognitive activities, i.e. (1) metacognitive awareness, (2) metacognitive evaluation and (3) metacognitive regulation. At least, 10 students were determined as research subject candidates who were organized by two groups. The first group consisted of students who were assigned to create an exemplification by using numbers, meanwhile another group contained of students who used some formula to solve the problem. Consequently, two research subject were taken from each groups. The data were collected by assignment sheet which was completed by the subject through think aloud and followed by interview based on the results of their works. The findings in this study showed that students who solved problems by making assumptions using numbers had 10 metacognitive failures, which included all red flags. Equally important that, students who used formulas in solving the problems had three metacognitive failures which included all red flags
Psychometric Properties of the Questionnaire “Demands and Potentials of ICT and Apps for Assisting People with Autism” (DPTIC-AUT-Q)

Background: In education, Information and Communication Technology (ICT) has gone from being a convenient option to a permanent necessity. For students and people with functional diversity, it is of seminal importance. It is therefore worth learning how professionals perceive digital tools and apps for people and students with functional diversity and autism: its requirements and potential. As no instrument to measure this exists, we have designed a questionnaire on the requirements and potentials of ICT and apps for assisting people with autism (DP-TIC-AUT). Methods: Our questionnaire has been subjected to content validity using a panel of experts, and construct validity, using Exploratory Factor Analysis and Confirmatory Factor Analysis, and Cronbach’s alpha and Composite Reliability. Results: Optimal results were obtained in the above values, thus confirming the validity of DP-TIC-AUT for use in the contexts of its validation. Conclusions: DP-TIC-AUT is a valid instrument. This opens up a range of possibilities for research, firstly descriptive, then of other kinds, and for the adaptation of the instrument to other contexts. This is the first step in improving the creation and use of ICT for people with autism.
Perception of Final Year Nigeria Nursing Students on Objective Structured Clinical Examination: A viewpoint of Oyo State College of Nursing and Midwifery, Eleyele, Ibadan, Nigeria

Objective Structured Clinical Examination (OSCE) is a kind of clinical assessment of nursing student’s skills. Therefore OSCE is used to sum the assessment of practical knowledge and skills in nursing education. In view of this, the paper dwells on investigation the perceptions of the final year nursing students on the Objective Structured Clinical examination and its acceptance among the students. The purpose of this research is to explore and investigate the perceptions of the final year nursing students, on the use of OSCE as a means of clinical practical assessment.