Miracle-dz/UniFAR-FTUs huggingface dataset:
From Lab to Market: Challenges Faced By Academic Entrepreneur in Technology Transfer Pursuit

The development of academic entrepreneurship is often benchmarked by the rate of patenting, licensing and spin-offs creation. However, these traditional indicators inherently require a long gestation period to materialize, thus creating a challenge to gauge the progress of novice universities. This paper preliminarily assesses the nature of academic entrepreneurship from a developing economy perspective and explore common challenges faced by academic entrepreneurs in bringing research discoveries from lab to market. Survey questionnaires were distributed to academic entrepreneurs of a public university in Malaysia and a series of answers to an open-ended question were analysed through content analysis. Although the results showed the rate of patents, licensing and start-up creations are modest, however, most of the scientists have made significant progress to the pre-commercialization stage by developing prototypes with commercial potential. The content analysis revealed that scientists’ entrepreneurial characteristics and institutional support were among the main factors that affect the commercialization of research discoveries. These findings suggest for the relevant authority to take improvement measures to enhance the efficiency of Technology Transfer Office and for the private funders and government disbursing agencies to provide more transparency in decision criteria and to reduce the period of application process and approval results. Avenues for future research are recommended based on the findings derived from this single case study.
Rhizobium lacunae sp. nov., Isolated From a Freshwater Pond

Bacterial strain designated CSW-27T was isolated from a freshwater pond in Taiwan. Cells were Gram-stain-negative, aerobic, oxidase-positive, catalase-negative, rod-shaped and motile by flagella. Strain CSW-27T grew at 20-40 oC (optimum, 30-37 oC), at pH 5-9 (optimum, pH 6-7) and in the presence of 0-4% NaCl (optimum, 0%). Phylogenetic analyses based on 16S rRNA gene sequences and an up-to-date bacterial core gene set revealed that strain CSW-27T was affiliated with species in the genus Rhizobium. Analysis of 16S rRNA gene sequences showed that strain CSW-27T had the highest similarity to Rhizobium straminoryzae CC-LY845T (98.5%) followed by Rhizobium capsici CC-SKC2T (96.9%). The average nucleotide identity, average amino acid identity and digital DNA-DNA hybridization values between strain CSW-27T and the closely related Rhizobium species were 73.4-86.5, 66.0-88.8 and 13.3-22.1%, respectively. The principal fatty acid was summed feature 8 (C18:1ω7c and/or C18:1ω6c). The main polar lipids were phosphatidylethanolamine, phosphatidylglycerol, diphosphatidylglycerol, phosphatidylmonomethylethanolamine, phosphatidyldimethylethanolamine, phosphatidylcholine, one uncharacterized aminophospholipid, three uncharacterized aminolipids and two uncharacterized lipids. The predominant polyamine was spermidine. The major isoprenoid quinone was Q-10. Genomic DNA G+C content of strain CSW-27T was 63.3%. These polyphasic taxonomic data indicited that strain CSW-27T should be considered as representing a novel species in the genus Rhizobium, for which the name Rhizobium lacunae sp. nov. is proposed with strain CSW-27T (=BCRC 81244T =LMG 31684T) as the type strain.
A proposed strategy for anticoagulation therapy in noncompaction cardiomyopathy

Noncompaction cardiomyopathy (NCCM) is a rare condition characterized by prominent trabeculae, deep intertrabecular recesses, and a left ventricular myocardium with a two‐layered structure, characterized by a spongy endocardial layer and a thinner and compacted epicardial one. NCCM can be isolated or associated with other congenital heart diseases and complex syndromes involving neuromuscular disorders and facial dysmorphisms. To date, more than 40 genes coding for sarcomeric, cytoskeletal, ion channels, and desmosomal proteins have been identified. Clinical presentation is also highly variable, ranging from no symptoms to end‐stage heart failure (HF), lethal arrhythmias, sudden cardiac death, or thromboembolic events. In particular, the prevalence of thromboembolism in NCCM patients appears to be higher than that of a similar, age‐matched population without NCCM. Thromboembolism has a multifactorial aetiology, which is linked to genetic, as well as traditional cardiovascular risk factors. In previous studies, atrial fibrillation (AF) was observed in approximately 25–30% of adult NCCM patients and embolism had a cardiac source in ~63–69% of cases; therefore, AF represents a strong predictor of adverse events, especially if associated to HF and neuromuscular disorders. Left ventricular dysfunction is another risk factor for thromboembolism, as a result of blood stagnation and local myocardial injury. Moreover, it is not completely clarified if the presence of deep intertrabecular recesses causing stagnant blood flow can constitute per se a thrombogenic substrate even in absence of ventricular dysfunction. For the clinical management of NCCM patients, an appropriate stratification of the thromboembolic risk is of utmost importance for a timely initiation of anticoagulant therapy. The aim of the present study is to review the available literature on NCCM with particular attention on thromboembolic risk stratification and prevention and the current evidence for oral anticoagulation therapy. The use of direct oral anticoagulants vs. vitamin K antagonists is also discussed with important implications for patient treatment and prognosis.
LES Simulation and Experimental Measurement of Fully Developed Ribbed Channel Flow and Heat Transfer

Ribbed channel flow is adopted for internal cooling of a 1300 °C class gas turbine first stage rotor blade. Heat transfer characteristics of transverse ribbed channel flow were examined using LES (Large Eddy Simulations) and by experiments. The flow was examined over the range of Reynolds number around 105 that are closer to the actual engine conditions. Computational results agreed reasonably well with experimental results. Heat transfer enhancement mechanism in a ribbed channel flow was shown to be caused by advecting eddy structure and interference of a rib.Copyright © 2002 by ASME
An investigation into the relationship between fiction and nonfiction reading exposure, and factors of critical thinking

Reading fiction has been associated with improved social and imaginative reasoning that could lead to improved critical thinking. This observational study investigated the relationship between fiction and nonfiction exposure, narrative transportation, and factors of critical thinking (critical thinking disposition, and epistemological orientation). Self-selecting participants (N = 335) completed an online survey including an author recognition test and self-report scales. Fiction scores were significantly associated with higher critical thinking disposition, while nonfiction had an inverse effect correlating with lower disposition. Fiction reading was associated with decreased absolutism, and nonfiction score conversely with higher absolutism. Total and nonfiction print exposure were associated with lower multiplism, with no significant association for fiction. Total and fiction print exposure were associated with higher evaluativism, with no significant association for nonfiction. Narrative transportation mediated some of these relationships. These findings provide a basis for further research into reading fiction and nonfiction, and critical thinking.
Performance of the floating gate/body tied NMOSFET photodetector on SOI substrate

In this paper, we report the performance of a new photodetector fabricated on SOI substrate using a standard CMOS process. The photodetector is formed by connecting the gate and the body of a NMOSFET. The gate-body terminal is left floating so that the potential can be modulated by illumination. The depletion region induced by the floating gate separates the optically generated electron-hole pairs in the direction perpendicular to the current. This increases the body potential and induces positive charges to the gate due to the tied gate and body. It results in a further turn on of the NMOSFET and extra optical current. The gain behavior under different illumination is characterized and explained by transistor theory. A wide signal range of more than six orders of magnitude and a high responsivity of about 1000 A/W have been obtained with an operating voltage as low as 0.2 V. The device scaling properties, noise behavior and transient response are also studied.
Stock Market Reactions on Shariah Indices Following Sukuk Issuances: CAAR Analysis on 2008-Financial Crisis

Pg. Abstract The purpose of this study is to look at how stock markets in Malaysia reacted to sukuk issuance announcements from 2004 to the post-2008 financial crisis by examining 50 selected companies listed in The FTSE Bursa Malaysia Kuala Lumpur Composite Index (FBMKLCI), FTSE Bursa Malaysia Emas Shari’ah Index (FBM EMAS), FTSE Bursa Malaysia Hijrah Shari’ah Index (FBM HIJRAH), and Dow Jones Islamic Market Index (DJIM). The data gathered from Datastream, Bloomberg, the Securities Commission Malaysia, and the Bursa Malaysia stock exchange were used to compile this study. A three-year estimation period to investigate market reactions using cumulative average abnormal return (CAAR) was adopted in this study. To investigate market efficiency, this study looked at symmetric and asymmetric event windows. This study discovers that markets responded favourably before the crisis but negatively and significantly during and after the crisis. The findings of this study provide advice to policymakers on how to direct regulators, investors, and issuers to the most stable sukuk during a crisis, as well as useful information and suggestions to issuers, policymakers, regulatory organisations, and investors in Islamic bonds.
Job Quality in the Late Career in Sweden, Japan, and the United States

Increasing numbers of older workers continue to work after being eligible to claim a state pension, yet little is known about the quality of these jobs. We examine how psychosocial and physical job quality as well as job satisfaction vary over the late career in three contrasting national settings: Sweden, Japan and the United States. Analyses using random effects modelling drew on data from the Swedish Longitudinal Occupational Survey of Health (n = 13,936–15,520), Japanese Study of Ageing and Retirement (n = 3704) and the Health and Retirement Study (n = 6239 and 8002). Age was modelled with spline functions in which two knots were placed at ages indicating eligibility for pensions claiming or mandatory retirement. In each country, post-pensionable-age jobs were generally less stressful, freer and more satisfying than jobs held by younger workers, results that held irrespective of gender or education level.
Energy and thermodynamic performance of LPG as an alternative refrigerant to R-134a in a domestic refrigerator

This paper presents an experimental investigation on the energy and thermodynamics performance of liquefied petroleum gas (LPG) as an alternative refrigerant to R-134a. LPG with 60 propane and 40 butane by mass fraction is used for the performance investigation. Thermodynamics performance such as co-efficient of performance, refrigeration effect, and compressor work, second law efficiency, and exergy losses have been investigated. The results show that LPG can be a possible alternative to R-134a in a domestic refrigerator. It is found that 60g LPG refrigerant has the lowest exergy loss () followed by 80g LPG. Highest exergy loss has been found when R134a is used as a refrigerant in a domestic refrigerator.
Age determination through DNA methylation patterns of fingernails and toenails

Over the past decade, age prediction based on DNA methylation has become a vastly investigated topic; many age prediction models have been developed based on different DNAm markers and using various tissues. However, the potential of using nails to this end has not yet been explored. Their inherent resistance to decay and ease of sampling would offer an advantage in cases where post-mortem degradation poses challenges concerning sample collection and DNA-extraction. In the current study, clippings from both fingernails and toenails were collected from 108 living test subjects (age range: 0 – 96 years). The methylation status of 15 CpGs located in 4 previously established age-related markers (ASPA, EDARADD, PDE4C, ELOVL2) was investigated through pyrosequencing of bisulphite converted DNA. Significant dissimilarities in methylation levels were observed between all four limbs, hence limb-specific age prediction models were developed using ordinary least squares, weighted least squares and quantile regression analysis. When applied to their respective test sets, these models yielded a mean absolute deviation between predicted and chronological age ranging from 6.71 to 8.48 years. In addition, the assay was tested on methylation data derived from 5 nail samples collected from deceased individuals, demonstrating its feasibility for application in post-mortem cases. In conclusion, this study provides the first proof that chronological age can be assessed through DNA methylation patterns in nails.
Use of minimum-adder multiplier blocks in FIR digital filters

The computational complexity of VLSI digital filters using fixed point binary multiplier coefficients is normally dominated by the number of adders used in the implementation of the multipliers. It has been shown that using multiplier blocks to exploit redundancy across the coefficients results in significant reductions in complexity over methods using canonic signed-digit (CSD) representation, which in turn are less complex than standard binary representation. Three new algorithms for the design of multiplier blocks are described: an efficient modification to an existing algorithm, a new algorithm giving better results, and a hybrid of these two which trades off performance against computation time. Significant savings in filter implementation cost over existing techniques result in all three cases. For a given wordlength, it was found that a threshold set size exists above which the multiplier block is extremely likely to be optimal. In this region, design computation time is substantially reduced. >
Effects of vitamin D3 injection in close‐up period on insulin resistance and energy balance in transition dairy cows

Abstract Background Many studies in dairy cows are towards calcium homeostasis and there is a lack of knowledge about the effect of vitamin D in preventing insulin resistance and improving energy balance in the transition period of dairy cows. Methods The trial was conducted in a commercial dairy farm with about 1500 lactating cows in Tehran province, Iran. Twenty‐four Holstein cows had been randomly selected and divided into control and treatment groups. In the treatment group, 12 cows, received a single dose of 8,000,000 IU vitamin D3 intramuscularly and in the control group, 12 cows were injected placebo (distilled water) 2–8 days before the expected calving time. Blood samples were collected between 8 and 10 AM 2 h after feeding on 21 and 7 days before calving and 1,3,7,15 and 30 days after calving. 25(OH)vitamin D, insulin‐like growth factor 1 (IGF‐1), insulin, nonesterified fatty acid (NEFA), β‐hydroxybutyric acid (BHBA), albumin, total protein, glucose, urea, triglyceride, cholesterol and aspartate amino transferase (AST) were measured by commercially available kits. The insulin resistance index was calculated. Results Vitamin D3 injection significantly affected the amounts of 25(OH) vitamin D, urea, insulin and insulin resistance index (p ≤ 0.05). On the other hand, the amounts of glucose, NEFA, BHBA concentration and AST activity were higher in control group (p ≤ 0.05). Time had a significant effect on the amounts of most measured variables except IGF‐1 and insulin. There were no group and time interactions for measured variables. Conclusion It seems that injection of vitamin D3 in close up period influenced lipolysis potentially modifying energy metabolism and resulted in reducing insulin resistance.
Model-Based Trajectory Prediction and Hitting Velocity Control for a New Table Tennis Robot

Currently, most table tennis robots concentrate on the canonical position control problem while ignoring the actual velocity control requirements. In this paper, we consider these requirements and propose a new table tennis robot framework. First, a tailor-made mechanical structure is designed such that the robot can reach large workspaces. Thereafter, in the table tennis trajectory prediction process, a clustering algorithm is introduced to screen the heterogeneous predicted hitting points and filter the invalid ones, thereby significantly improving the prediction accuracy. By using quintic polynomial trajectory planning, smooth and stable high-speed control of the robot hitting motion can be obtained. Finally, a position-based strategy and a velocity-based strategy are devised for returning the table tennis. Extensive experiments demonstrate that the accuracy of the ball's trajectory prediction algorithm is more than 92%. The success rate of returning the ball exceeds 95% at the ball velocity of 3-7 m/s, and the velocity-based strategy performs better compared with the position-based approach at the ball velocity of 7-9 m/s.
Geographic health inequalities in Madrid City: exploring spatial patterns of respiratory disease mortality

The unequal geographic distribution of health determinants could denote situations of environmental injustice. This work aims to identify spatial patterns of respiratory disease mortality and their association with the education level and the atmospheric pollution in Madrid. To this purpose, we applied spatial analysis through statistical techniques and Geographic Information Systems at the census tract level. The analysis showed a slight but significantly higher risk of mortality in areas with more unfavourable socioeconomic and environmental conditions. This work has the potential to inform public policy and research on links among social, environmental and health inequalities in Madrid City.
The results of a 24-month controlled, prospective study of relapsing multiple sclerosis patients at risk for progressive multifocal encephalopathy, who switched from prolonged use of natalizumab to teriflunomide

Background Natalizumab (NTZ) is a highly effective disease modifying treatment for relapsing multiple sclerosis (RMS), but it increases risk of progressive multifocal leukoencephalopathy (PML) in patients with serum anti- John Cunningham virus (JCV) antibodies. Objective To assess the safety and efficacy of rapid transition, from NTZ to teriflunomide (TFM) in RMS patients. Methods Clinically stable NTZ-treated, anti-JCV antibody positive RMS patients were switched to TFM 28 ± 7 days after their last dose of NTZ. The primary endpoint was proportion of relapse free patients at 24 months. Results Median [IQR] age of the 55 enrolled patients was 47 [40.7, 56.3] years, 76% were female. The median [IQR] number of prior NTZ treatments was 34 [18, 64]. annualized relapse rate (ARR) was 0.07 and 77% of the patients were relapse free at 24 months. Mean time to first GAD + lesion was 19.6 months, and to new/enlarging T2 lesion was 19.2 months. Mean time to 3 month sustained disability worsening (SDW) was 22 months and proportion free of 3-month SDW was 0.87. There were no cases of PML. Conclusions The washout-free transition of NTZ to TFM was an efficacious and safe strategy for patients at risk of developing PML. ClinicalTrials.gov Identifier: NCT01970410
Performance of Integrated Pest Management Practices in Production of Bt Cotton in Karimnagar District of Andhra Pradesh - A Case Study

Integrated Pest Management in cotton production was demonstrated under Front Line Demonstration (FLD) in two villages in Karimnagar district of Andhra Pradesh during 2008–09 to 2010–11. The results revealed that IPM practices were superior in controlling aphids, mealy bug and Spodoptera as the incidence of these pests was significantly lower in the production of cotton. The activity of beneficial insects also improved in IPM fields when compared with non IPM fields. Seed cotton yield obtained was 16.6% higher in IPM fields than non IPM fields. Higher net returns ( 54217/ha) and B:C ratio 2.69 registered in IPM fields compared to non IPM fields ( 40488/ha and 2.15, respectively).
THE EFFECTS OF GREEN-CANE TRASH BLANKET ON SOIL TEMPERATURE, SOIL MOISTURE AND SUGARCANE GROWTH

GREEN cane harvesting and trash blanketing (GCTB) is being increasingly adopted in the sugarcane area of Tucuman Argentina. These practices result in lower environmental impacts, cost reduction in weed control, and an improvement in soil moisture conservation. The effects of a trash blanket on the soil temperature and soil moisture regimes were studied in a field trial by comparing burning of post-haivest residues PC) and GCTB systems under irrigated and rainfed conditions during four growing periods. The impact on stalk population, stalk growth, number of leaves and weight of millable cane was evaluated. Soil temperature was 1.5"C higher at emergence and tillering where the residue was burned as compared to the GCTB system. After these periods, the differences were no longer significant. In all cases, the temperature remained above the 10S°C base temperature for Tuc 77-42 growth. The trash blanket also modified the soil moisture regime, and variations in soil rnoist~~re were closely related to rainfall distribution. Periods with moisture contents above 40% of the available water in the top 45 cm were 40 days during dry springs and 80 days during humid springs for the GCTB whereas, in the burnt residue plots, they were 20 days and 50 days, respectively. Differences in the number of stalks at harvest were not obtained for the two systems; however, there were more shoots where the residue was burned at the tillering phase. Changes in the temperature and moisture regimes in the top 45 cm caused by the trash blanket had no adverse effect on cane yield. This infonnation can be used by the growers of Tucunlh to justi@ the adoption of green cane trash blanketing in their farming operations.