Miracle-dz/UniFAR-FTUs huggingface dataset:
The Open Journal of Occupational Therapy The Open Journal of Occupational Therapy

Abstract Background:: Universal design for learning (UDL) is considered best-practice for embracing inclusion for students with disabilities and there is growing evidence of its effectiveness in primary, secondary, and postsecondary education. However, little is known about if and how UDL is being implemented into United States graduate allied health and medical school curriculum as well as evidence of its benefits. Method: We used Arksey and O’Malley’s (2005) methodological framework. Search engines were: PubMed, CINAHL Complete, ERIC, GoogleScholar, and Scopus. Data were analyzed by the research team using Covidence to organize articles, screen, and complete a full-text review. Data extraction was completed by identifying key themes in the manuscripts and categorizing articles accordingly. Results: Six studies were eligible: three intervention and three descriptive articles. Findings identify a need for UDL in these programs but research regarding the effect of implementation of this framework into medical and allied health programs is lacking. Conclusion:: There is a scarcity of research on UDL in graduate education from the United States. Much of the literature found on use of UDL in medical and allied health graduate level programs is non-experimental or descriptive. Future research is recommended to examine the impact of UDL in graduate education.
ISPITIVANJE KORELACIJE NIVOA GUBITKA ALVEOLARNE KOSTI U INTERDENTALNOM I INTERRADIKULARNOM PROSTORU PRIMENOM RADIOGRAFSKE ANALIZE EXAMINATION OF CORRELATION OF LEVELS OF ALVEOLAR BONE LOSS IN INTERDENTAL AND INTERRADICULAR SPACE USING RADIOGRAPHIC ANALYSIS

Introduction: One of the consequences of the presence of periodontitis is the loss of alveolar bone in the interdental and interradicular space. Bone loss is very important for assessing the severity of the disease and a pplying therapeutic procedures. Aim: The objective was to determine and compare the loss of interdental and interradicular alveolar bone using radiographic analysis. Material and methods : 1 00 patients, aged 40 to 60 years, with chronic periodontitis and involvement of grade III and IV furcations in mandibular molars were examined. After orthopantomograph ic imaging, morphological measurements of mesial and distal interdental bone loss were performed, as well as the measurements of interradicular space. Then, their interrelationship was analyzed. Results: The mean value of mesial in terdental bone loss was 5.90 ± 2.4mm, and the mean value of distal was 6.1 ± 6.1mm, while the mean value of interradicular bone loss was 3. 55 ± 5.1mm. The correlation between interradicular and interdental bone loss was statistically significant (p<0.001). A higher correlation was present in respondents older than 50 years compared to younger respondents. Regarding gender, no statistically significant difference was observed between the examined bone levels. Interradicular bone loss of 0.8 mm and more was observed in subjects with bone loss in the interdental area of at least 3.7 mm. Conclusion: The results show that there is a correlation between the loss of alveolar bone levels in the interdental and interradicular space of the molars in chronic periodontitis, so interdental and interradicular bone loss can be used as an additional test in diagnosing the disease. Additional research is needed, which would include the use of three-dimensional radiography to determine the severity of the disease and therapeutic procedures.
ON CREATIVE BEHAVIOR

: Over the last decade, much research has been conducted in the field of quality of work life(QWL) and its associations with the creative behavior of employees. Prior studies have found substantial positive evidence for statistical associations between QWL and creative behavior. The purpose of this study is to investigate the relationships between QWL dimensions and creative behavior. This study examines the relationships between QWL dimensions and creative behavior. The researcher adopted the descriptive survey design. Primary data was sourced through the instrument of the questionnaire. It was given to a chosen group of (110) workers. A percentage of (90%) was obtained from retrieving (62) valid questionnaires. The research study is drawn scientifically using the simple random sampling technique. The findings revealed the institution under study professors' creative behavior correlates with the quality of work life in all dimensions (work characteristics, work environment, participation, compensation, supervision, and working group). The institution under study professors' creative behavior is impacted by a combination of work-life quality dimensions. It also discovered an average quality of work life and creative behavior of the institution in question. The researcher recommended, among others that the (institution under study) should pay more attention to the quality of work life by paying attention to the work environment by providing a healthy, safe work environment (security equipment and protection from occupational hazards in the workplace), and comfortable at work from Where (cleanliness, lighting, humidity, ventilation, housing as well as office and logistical equipment, laboratories, and technical and scientific equipment required to finish and stimulate research work. The Faculty of Applied Sciences of the University of Kasdi Merbah Ouargla advises that training sessions and awareness campaigns be held to raise awareness of the system of salaries, wages, rewards, and employees' obligations to their jobs.
Digital Comprehensive Summaries of Uppsala Dissertations from the Faculty of Science and Technology 1312 Discovery and evaluation of direct acting antivirals against hepatitis C virus

Abdurakhmanov, E. 2015. Discovery and evaluation of direct acting antivirals against hepatitis C virus. Digital Comprehensive Summaries of Uppsala Dissertations from the Faculty of Science and Technology 1312. 49 pp. Uppsala: Acta Universitatis Upsaliensis. ISBN 978-91-554-9398-1. Until recently, the standard therapy for hepatitis C treatment has been interferon and ribavirin. Such treatment has only 50% efficacy and is not well tolerated. The emergence of new drugs has increased the treatment efficacy to 90%. Despite such an achievement, the success is limited since the virus mutates rapidly, causing the emergence of drug resistant forms. In addition, most new drugs were developed to treat genotype 1 infections. Thus, development of new potent antivirals is needed and drug discovery against hepatitis C is continued. In this thesis, a FRET-based protease assay was used to evaluate new pyrazinone based NS3 protease inhibitors that are structurally different to the newly approved and currently developing drugs. Several compounds in this series showed good potencies in the nanomolar range against NS3 proteases from genotype 1, 3, and the drug resistance variant R155K. We assume that these compounds can be further developed into drug candidates that possess activity against above mentioned enzyme variants. By using SPR technology, we analyzed interaction mechanisms and characteristics of allosteric inhibitors targeting NS5B polymerases from genotypes 1 and 3. The compounds exhibited different binding mechanisms and displayed a low affinity against NS5B from genotype 3. In order to evaluate the activity and inhibitors of the NS5B polymerase, we established an SPR based assay, which enables the monitoring of polymerization and its inhibition in real time. This assay can readily be implemented for the discovery of inhibitors targeting HCV. An SPR based fragment screening approach has also been established. A screen of a fragment library has been performed in order to identify novel scaffolds that can be used as a starting point for development of new allosteric inhibitors against NS5B polymerase. Selected fragments will be further elaborated to generate a new potent allosteric drug candidate. Alternative approaches have successfully been developed and implemented to the discovery of potential lead compounds targeting two important HCV drug targets.
The Open Journal of Occupational Therapy The Open Journal of Occupational Therapy

Abstract Background:: Hand therapy clinical rotations are 12 weeks, and one common anecdotal change frequently expressed is an increase in hand strength. Quantifiable measures of change are not documented in the literature. The purpose of this study is to determine if students experience significant increases in strength during a clinical rotation. Methods:: This study is a quasi-experimental, double-blinded, non-randomized sample of convenience. Grip and pinch strength were assessed pre, mid, and post clinical rotation. Demographic data were collected and reported. Paired t-tests were used to compare means between groups. SPSS 27.0 was used for data analysis. Results:: After removing incomplete data sets, n = 12. Grip strength in the left hand showed a significant increase from pretest to posttest. Grip strength in the right hand showed no difference. Significant increases occurred in both right and left tripod pinch and lateral pinch strength from pretest to posttest. A significant increase was not observed for 2-point pinch strength. Discussion:: This study provides insight into the changes in hand strength in students after a clinical rotation in hand therapy. Significant changes in grip and pinch strength do occur during this time. Increased load in grip and pinch patterns may have clinical implications for therapists practicing long term.
Haematology and Comparative Study of Fluted Pumpkin Leave Vegetable and Seed Nutrients ( Telfairia occidentalis ).

Fluted Pumpkin has been documented for high levels of potassium and iron in its leaf vegetable and edible seed, it is consume for its blood enrichment against anemia patients. The aim of the study is to determine the haematology and compare fluted pumpkin leave and seed nutrients. The formulations combination is as follows Animal Feed, pumpkin Leave and Nitrogen Free Diet (APLN), 10%, 10%, 80%, Animal feed pumpkin seed and Nitrogen Free Diet (APSN) 10%, 10%, 80%, Animal Feed and Nitrogen Free Diet (ANFD) 10%, 10%, 80%, and Nitrogen Free Diet (NFD) 100%. Growth response progressed with APSN 30%, APSN 2% and ANFD 33.5% NFD and retrogressed by 15.9%. The study revealed that heamatology study, such as LYM#-3/UL, LYM%, MCHC g/dl, RBC-6/ UL RDW-CV% RDW-CV% was high above the limit compared with the healthy patients. In conclusion vegetables meal such as fluted pumpkin leaf (ugu) contain a high amount of dietary fibre that can help to lose weight. Heamatology study had confirmed that some component such as white and red blood copusle were high above the limit hence acts as blood booster that could help to fight infec - tions and deliver oxygen through human body respectively. However, comparing the leaf with the seed of fluted pumpkin nutrients, the leaf had the best performance. The nutrient content in leaf was favourably compared to control diet in terms of biological values and nitrogen retention.
Assessing the Dynamic Relationship Between Small and Large Assessing the Dynamic Relationship Between Small and Large Cap Stock Prices Cap Stock Prices

: The historical long-run return on small capitalization stocks has unquestionably outperformed large capitalization stocks since 1926. The phenomenon of small capitalization stocks having higher risk-adjusted returns compared with large capitalization stocks is an equity market anomaly first discovered in 1981. Since then, many academics and investors have strongly argued that “size is dead”. This paper argues that far from being dead, the phenomenon of size effect appears alive and well and it could be exploited effectively over long-term investment horizons. To analyze this phenomenon, we focus specifically on the dynamics of small cap and large cap prices. We test for multivariate cointegration among the small cap and large cap stock prices and other major macroeconomic factors from 1980 to 2006. After conducting robustness tests on forward recursive and ten year rolling samples, we find evidence of one long-run cointegrating vector. Of more importance, there is a consistently negative and highly significant relationship between small and large cap stock prices. This could suggest that the size effect exhibits a cyclical pattern. Our analysis also provides supporting evidence that the size effect appears to exhibit predictable reversals when considering long investment horizons. Furthermore, we demonstrate how small cap stocks can be viewed as less risky than large cap stocks over long holding periods. Finally, we make suggestions on how asset managers and individual investors can enhance returns based on our overall results.
Detection and Tracking of Aircraft in the Far-Field from Small Unmanned Aerial Systems

Onboard far-field aircraft detection is needed for safe non-cooperative traffic mitigation in autonomous small Unmanned Aerial System (sUAS) operations. Machine vision systems, based on standard optics and visible light detectors, possess the ideal size, weight, and power (SWaP) requirements for sUAS. This work presents the design and analysis of a novel aircraft detection and tracking pipeline based on optical sensing alone. Key contributions of the work include a refined range inequality model based on sensing and detection with FAA well-clear separation assurance distances between aircraft in mind, a detector fusion method to maximize the benefit of two image detectors, and a comparative analysis of Linear Kalman-filtering and Extended Kalman-filtering to seek optimal tracking performance. The pipeline is evaluated offline against multiple intruder platforms, using two types of flight encounters: multirotor sUAS vs. fixed-wing sUAS and multirotor sUAS vs. general aviation (GA) plane. Analysis is restricted to the rate-limiting head-on and departing collision volume cases vertically separated for safety. Results indicate that it is feasible to use the proposed optical spatial-temporal tracking algorithm to provide adequate alerting time to prevent penetration of well-clear separation volumes for both sUAS and GA aircraft.
Evidence of kilometer-wide shallow bulk plastic yielding along the 2021 Maduo, Tibet, surface rupture, and its relation with the dynamic rupture process

Surface deformation associated with continental earthquake ruptures includes localized deformation on the faults, as well as deformation in the surrounding medium though distributed and/or diﬀuse processes. However, the connection of the diﬀuse part of the surface deformation to the overall rupture process, as well as its underlying physical mechanisms are not yet well understood. Computing high-resolution optical image correlations for the 2021/05/21 Mw7.4 Maduo, Tibet, rupture, we highlight a correlation between the presence of faults and fractures at the surface, and variations in the across-fault displacement gradient, fault zone width, and amplitude of surface displacement. We show that surface slip along primary faults is systematically associated with gradients greater than 1%, and is dominant in regions of greater coseismic surface displacement. Conversely, the diﬀuse deformation is associated with gradients [? ]0.3%, and is dominant in regions of lesser surface displacement. The distributed deformation then occurs for intermediate gradients of 0.3-1%, and at the transition between the localized and diﬀuse deformation regions. Such patterns of deformation are also described in laboratory experiments of rock deformation, themself supported by ﬁeld observations. Comparing these experiments to our observations, we demonstrate that the diﬀuse deformation along the 2021 Maduo rupture corresponds to kilometer-wide plastic yielding of the bulk medium occurring in regions where surface rupture is generally missing. Along the 2021 Maduo rupture, diﬀuse deformation occurs primarily in the epicentral region, where the dynamic stresses associated with the nascent pulse-like rupture could not overcome the shallow fault zone frictional strength.
Factors Determining Mortality of Adult Chaparral Shrubs in an Extreme Drought Year in California

We measured dieback and mortality in a chaparral shrub community at a chaparral/desert ecotone following four years of below-average rainfall. Ecotones are important systems in which to examine plant and community responses to extreme and prolonged drought conditions and the potential impact of global change on plant distributions and community composition. Following a particularly severe drought year, dieback and mortality were documented for seven co-dominant shrub species. We examined whether mortality was related to species ecology, leaf traits, or water relations. Dieback and mortality were greatest in two non-sprouting species. These species also had high xylem cavitation resistance and low specific leaf area compared to several sprouting species. Among two sprouting congeners, mortality was greater in the more shallowly rooted species, even though this species was more cavitation resistant. Across all species, those that were more resistant to cavitation had greater mortality. Evidently, high resistance to xylem cavitation does not prevent adult plant mortality at chaparral/desert ecotones. A series of extreme drought years could preferentially reduce or eliminate non-sprouting species from mixed chaparral populations, causing a shift in community structure and contributing to desertification.
In today’s

The convergence of artificial intelligence (AI) and environmental, social and governance (ESG) factors is a pivotal development in today’s rapidly evolving business landscape. In this paper we provide an in-depth analysis of the symbiotic relationship between AI and ESG, outlining how AI technologies can be applied to enhance ESG management and mitigate related risks. EY teams discuss ESG’s significance in today’s world and its synergy with AI technologies. It also scrutinizes how AI can be a catalyst in achieving ESG objectives, from environmental sustainability to social responsibility and governance. We conclude with a critical evaluation of AI’s impact on ESG metrics and offer actionable insights for mitigating potential challenges.
Evaluating the Saudi EFL Teachers’ Perceptions of Concept Evaluating the Saudi EFL Teachers’ Perceptions of Concept Mapping Instruction: A Pedagogical Perspective Mapping Instruction: A Pedagogical Perspective

: The current study evaluated the Saudi EFL teachers’ perceptions of using concept mapping as an instruction method for teaching English to Saudi Middle school students. In this regard, the current study investigated the Saudi EFL teachers of employing the concept mapping instruction in terms of various elements, namely its benefits, challenges, learning outcomes, students’ comprehension of language content, and students’ retention of language knowledge. Data was elicited through a 35-item questionnaire that was divided into six parts. The study employed a qualitative research design to gather insights into the Saudi EFL teachers’ perceptions regarding various elements of the concept mapping implementation. The sample comprised 40 (n=40) Saudi EFL teachers from 12 Middle Schools across Al-Majmaah city selected through purposive sampling. The findings align with existing literature, highlighting the potential of concept mapping to enhance students’ active engagement, critical thinking, knowledge retention, language abilities, and content comprehension, as well as the challenges faced by teachers during implementation. The pedagogical implications recommended incorporating the concept mapping into educational policies, curriculum design, and Saudi EFL teachers’ training programs in order to enhance the quality and effectiveness of English language teaching in the Saudi EFL context.
What Underlies Focal Colours?

Colour names are generally attributed to specific colour categories, of which the most representative colour is termed a focal colour. The question as to what underlies this categorization is addressed in this paper. Are the categories simply a naming convention of colours with a specific ‘perceptual salience? ’ Results based on the wraparound Gaussian model of reflectances show that colour categories follow naturally from a perception-agnostic segmentation of colours defined in this space. In other words, a segmentation based only on colour coordinates, not perceived colours. Furthermore, it is demonstrated that the concept of a focal colour can be explained as a colour that is both (i) representative of a colour category, and (ii) relatively stable under a wide range of illuminant spectra without depending upon chromatic adaptation.
Thinkpiece THE VARIETIES AND REVISIONS OF ATHEISM

The philosopher Antony Flew has argued for decades that theistic arguments cannot meet criteria of truth. In this essay I respond to Flew’s recent announcement that research into the emergence of DNA provides grounds for rational belief in an intelligent orderer, a “God. ” Flew’s theistic turn is important for philosophers of religion and the wider science-and-religion dialogue. It becomes apparent, however, that Flew’s “conversion” is not as decisive as one might imagine. While he admits growth in scientific and philosophical understanding, he rejects the idea of growth in religious understanding. Further, he endorses a version of “theoretical theism” while denying the practical importance of belief. Such denial of practical conviction is part of a modernist mindset that separates freedom from the embeddedness of human beings in the natural world. I conclude by noting that the entanglement of human action and wider physical processes, an entanglement seen emblematically in the environmental crisis, requires not only considering the importance of intelligence and order in the emergence of life but also the significance of human agency in claims about the divine and the natural world.
NEURAL MANIFOLDS AND GRADIENT-BASED ADAPTATION IN NEURAL-INTERFACE TASKS

Neural activity tends to reside on manifolds whose dimension is much lower than the dimension of the whole neural state space. Experiments using brain-computer interfaces with microelectrode arrays implanted in the motor cortex of nonhuman primates tested the hypothesis that external perturbations should produce different adaptation strategies depending on how “aligned” the perturbation is with respect to a pre-existing intrinsic manifold. On the one hand, perturbations within the manifold (WM) evoked fast reassociations of existing patterns for rapid adaptation. On the other hand, perturbations outside the manifold (OM) triggered the slow emergence of new neural patterns underlying a much slower—and, without adequate training protocols, inconsistent or virtually impossible—adaptation. This suggests that the time scale and the overall difficulty of the brain to adapt depend fundamentally on the structure of neural activity. Here, we used a simplified static Gaussian model to show that gradient-descent learning could explain the differences between adaptation to WM and OM perturbations. For small learning rates, we found that the adaptation speeds were different but the model eventually adapted to both perturbations. Moreover, sufficiently large learning rates could entirely prohibit adaptation to OM perturbations while preserving adaptation to WM perturbations, in agreement with experiments. Adopting an incremental training protocol, as has been done in experiments, permitted a swift recovery of a full adaptation in the cases where OM perturbations were previously impossible to relearn. Finally, we also found that gradient descent was compatible with the reassociation mechanism on short adaptation time scales. Since gradient descent has many biologically plausible variants, our findings thus establish gradient-based learning as a plausible mechanism for adaptation under network-level constraints, with a central role for the learning rate.