Miracle-dz/UniFAR-FTUs huggingface dataset:
Application of Gundelia tournefortii L. in yoghurt

Yoghurt is a fermented milk product consumed in the entire world. It is easily digested, has high nutritional value and is a rich source of carbohydrates, protein, fat, vitamins, calcium and phosphorus. Several yogurt-based products are marketed with the addition of either fruit or vegetables rich in bioactive food ingredients or edible fibers claimed to have beneficial effects on human health product. Gundelia tournefortii L.is a member of the Asteraceae (Compositae) family which grows in the semi-desert areas of Iran, Jordan, Palestine, Syria, Iraq, Syria, Anatolia and other countries. Traditionally, G.tournefortii L. is used for treatment of liver diseases, diabetes, chest pain, heart stroke, gastric pain, vitiligo, diarrhea and bronchitis. It is also reported to have hypoglycemic, Laxative, sedative, anti-inflammatory, anti-parasite, antiseptic and emetic effects. Compounds found in G. tournefortii proved to have several pharmacological effects, e.g. antibacterial, anti-inflammatory, hepatoprotective, antioxidant, antiplatelet and hypolipemic activities. The observed pharmacological properties indicated a close association of these effects with infectious diseases, digestive disorders, high blood pressure and cancer. In traditional medicine, this plant has been prescribed in many disorders. Dairy together with fruit and vegetable ingredients may get transformed into ‘functional foods’ that is gaining grounds in recent years. KEY WORD: Gundelia tournefortii, Yoghurt, Pharmacological effects, Traditional medicine.
GENETIC POLYMORPHISM AND SERUM LEVEL OF VASCULAR ENDOTHELIAL GROWTH FACTOR ASSOCIATED WITH FIRST TRIMESTER PREGNANCY OUTCOME IN ICSI PROGRAM

VEGF plays an important role in normal physiological processes that require increased vascularization to bring oxygen and nutrients to tissues, including embryonic development. This study determine the relationship between changes in serum level of vascular endothelial growth factor (VEGF) protein and pregnancy outcome in women undergoing ICSI and also the relationship between (VEGFA) single nucleotide polymorphism (rs 3025039) 936 C/T and it’s incidence on pregnancy outcome after ICSI. The study was done on 51 infertile women and 34 fertile women with at least 2 live births. Patients categorized as pregnant, non-pregnant and miscarriage. The levels of vascular endothelial growth factor protein were measured by ELISA, the results showed that the levels of vascular endothelial growth factor in control, ICSI patients, pregnant, non-pregnant and miscarriage were (1.99±0.54mg/ml, 2.46±0.64mg/ml, 2.80±0.61mg/ml, 2.21±0.60mg/ml, 2.56±0.30 mg/ml respectively). The significant increase shown in pregnant when compared with control, pregnant p= 0.0004, (p<0.05) and also there is significant increase in pregnant when compared with non-pregnant, p=0.0081, (p<0.05). The genetic polymorphism VEGFA/rs 3025039 was detected by specific primers. Results of amplification showed that a DNA fragment 198 bp was obtained after electrophoresis on 2% agarose gel. The nucleotide sequence of each amplified fragment was determined. Results of sequencing showed that the genotype frequency in control were CC (85.29%), CT (11.76%), TT (2.94%), in ICSI patients were CC (72.54%), CT (23.52%), TT (3.92%), in pregnant were CC (62.5%), CT (16.66%), and TT (0%), in non-pregnant were CC (70%), CT (25.92%),TT (3.7%) and in In miscarriage World Journal of Pharmaceutical Research SJIF Impact Factor 7.523 Volume 6, Issue 16, 67-76. Research Article ISSN 2277– 7105 *Corresponding Author Luma Waad Abdul Alteef
Assessment of Heavy Metals in Cassava Mill Effluents Contaminated Soil in a Rural Community in the Niger Delta Region of Nigeria

This study assessed the level of some selected heavy metals in cassava mill effluents contaminated soil from Ndemili community in the Niger Delta region of Nigeria. Triplicate soil samples were collected using soil augar at 0 20 cm depth from 6 locations including one control. Sampling was carried out bimonthly (from November 2016 to September 2017) covering the two predominant seasons wet and dry. The samples were dried, digested and analyzed using flame atomic absorption spectrophotometer (FAAS). Result for both spatial and bimonthly distribution of heavy metals for copper 1.10 6.83 mg/kg, zinc 14.32 46.15 mg/kg, manganese 18.42 47.49 mg/kg, iron 1303.29 4934.04 mg/kg, lead 1.33 9.42 mg/kg, cadmium < 0.001 0.24 mg/kg, chromium 0.19 3.41 mg/kg, nickel 1.57 3.76 mg/kg and cobalt < 0.008 9.71 mg/kg. Analysis of variance showed that there was significant variation (P < 0.05) among the various locations, months and interaction of locations and months apart from iron and chromium in the bimonthly distribution. Positive significant correlation (P < 0.05) also exists among most of the heavy metals, indicating that contamination is of similar origin apart from cadmium that showed negative correlation with cobalt. The study showed that cassava mill effluents are having impact on soil receiving the effluent with regard to heavy metals concentration.
PSYCHOMOTOR TRAINING PROGRAM WITH ELEMENTS OF THEAT RICAL PLAY ON MOTOR PROFICIENCY AND COGNITIVE SKILLS OF PRESCHOOL ERS

The purpose of this study was to examine the effect of a psychomotor training program with elements of theatrical play, upon the cognitive skills and motor proficien cy of 41 Greek preschoolers who attended in two sep arate regular schools, in Heraklion, Crete. The two schools rando mly served as the experimental EG (N= 20 students ) and control CG (N=21 students) groups. The BruininksOseretsky Te st of Motor Proficiency -Short Form (BOTMP – SF) (B ruininks, 1978) assessed the motor skills, while the ATHENA t est (Paraskevopoulos & Paraskevopoulou, 2011) asses sed the cognitive skills. The EG followed a ten week prog ram, twice per week. The program was designed accor ding to the psychomotor development theory (Zimmer, 2007) enric hed with theatrical play. 2 X 2 MANOVA, with t-para meter estimates for post hoc comparisons were used for st atistical analyses of motor proficiency. Significan t i teraction effects with respect to ‘general motor proficiency’ was fou nd. With respect to cognitive skills separate 2 X 2 ANOVAs were used and the results were significant for ‘language prop o tions’, ‘vocabulary’, ‘picture memorization’, ‘di stinction of graphs’, ‘complete proposals’ and ‘word completion’. The res ult provided implications for curriculum design, e ffective teaching and preparing future teachers to work with alternat ive ways.
DPPH free radical scavenging activity of phenolics and flavonoids in some medicinal plants of India

Plants have enormous ability to synthesize aromatic substances mainly secondary metabolites, of which at least 12,000 have been isolated. In many cases, these substances serve as the molecules of plant defense against predation by microorganisms, insects, and herbivores. Further, some of which may involve in plant odour (terpenoids), pigmentation (tannins and quinines) etc. It is now clear that, the medicinal values of these plants lie in the bioactive phytochemical constituents. They are also responsible to produce definite physiological effects. ISSN: 2319-7706 Volume 4 Number 1 (2015) pp. 773-780 http://www.ijcmas. com
Correlative study between modified mallampati score with Cormack Lehane and POGO scoring

Background: Assessing the difficulty level of the airway for intubation is extremely important in anaesthetic practice to avoid delays in intubation and resulting adverse consequences. Multiple grading systems are used by anaesthesiologists across the globe to aid in classifying the airways, but the number of studies assessing the level of agreement between various methods is scarce. Hence, the current study was conducted with an objective of assessing the level of agreement of Modified Mallampatti score (MMS) with Cormack –Lehane scoring and POGO Scoring. Materials and methods: The study was a cross sectional study, conducted in the Department of Anesthesiology, Government Mohan Kumaramangalam Medical College and Hospital, Salem, Tamil Nadu on adults aged between 18 to 65 years, belonging to ASA grade 1 and 2, scheduled for elective and emergency surgery under general anaesthesia. Patients with apparent restriction of mouth opening due to pain, with fresh facial injuries and dental abnormalities were excluded from the study. The airway of each subject was assessed by the trained anesthetist, in charge of the procedure. The agreement between the different methods of grading was assessed by kappa Statistic along with its standard error and P value. P value < 0.05 was considered as statistically significant. Results: A total of 236 subjects were included in the study. Among the study population, 74 (31.36%) had mallampatti grade I. The number of mallampatti grade II, III, and IV was 140 (59.32%), 21 (8.90%) and 1 (0.42%) respectively. Among the study population, 143 (60.59%) had Cormack Lehane grade I. The number of Cormack Lehane grade II, and III was 84 (35.59%), and 9 (3.81%) respectively. Among the study population, 170 (72.03%) had POGO grade 1. The number of POGO grade 2, 3 and 4 was 42 (17.80%), 15 (6.36%), and 9 (3.81%) respectively. The measure of agreement was very poor between Mallampatti grading with Cormack Lehane grading. (kappa statistics value K. Murugesan, Arunachalam R, Rajarajan N. Correlative study between modified mallampati score with Cormack Lehane and POGO scoring. IAIM, 2018; 5(4): 119-125. Page 120 0.103, P value 0.032). The measure of agreement was also very poor between Mallampatti grading and POGO grade. (kappa statistics value was 0.105, P value 0.004). The measure of agreement was fair between Cormack Lehane grading and Mallampatti grading. (kappa statistics value was 0.327, P value <0.001). Conclusions: When compared to POGO score, Cormack Lehane grading had shown a better level of agreement with Mallampatti grading. But the level of agreement between any of the two methods was too low to rely on them interchangeably in clinical practice.
Journal of Diabetes and Obesity

The prevalence of obesity and overweight in most population is increasing alarmingly. This rise is associated with economic development, increasing urbanization, change in dietary and other lifestyle patterns and also reduced physical activity. Last studies showed that type 2 diabetes incidence rise with increasing body mass index (BMI). This paper evaluated the prevalence of overweight and obesity among diabetic patients. A total of 518 consecutive central-based patients (198 males and 320 females) with type 2 diabetes (T2DM) were investigated in this prospective cross-sectional study. The overall prevalence of overweight and obesity (BMI>25 kg/m2) was 76%. The mean of BMI in women was 26.66 ± 3.98 and in men was 28.70 ± 4.36. The prevalence of overweight and obesity were 48% and 28%, respectively. This paper indicated a high prevalence of overweight and obesity in diabetic patients in Yazd (central province of Iran). *Corresponding Author: Masoud Rahmanian, Yazd Diabetes Research Center, Shahid Sadoughi Ave, Yazd, Iran. Tel: 009837280226; Fax: 009837280216; E-mail: rahmanian@ssu.ac. ir
Effect of Substitution of Date Pits in Concentrate Feed on Growth Performance and Nutrients Digestibility of Ardi Goats

In Saudi Arabia, goats are one of the major sources of milk and meat. Goats are very tough animal that can survive under harsh environmental conditions. The main aim of this study was to evaluate the effect of substituting four levels (0, 10, 15 and 20%) of date pits with concentrate feed on nutrients digestibility and growth performance of Ardi goats. Twenty goats were randomly selected and distributed into four treatment groups with each group of 5 goats. Goats fed 60% alfalfa hay and 40% concentrate feed containing either 0, 10, 15 or 20% date pits. There were no significant difference among all the dietary treatments on Dry Matter Intake (DMI) and nutrient intakes. The Feed Conversion Ratio (FCR) and daily gain weight were significantly higher in goats fed on a concentrate feed containing 0 and 20% date pits than those fed on a diet containing 10% date pits while no significant difference was observed in goats fed on a diet containing 15% date pits. The digestibility coefficients of Dry Matter (DM), Organic Matter (OM), Crude Protein (CP) and Neutral Detergent Fiber (NDF) were significantly (p#0.05) higher in goats fed on a concentrate feed containing 0 and 20% than those fed with feed containing 10 and 15% date pits. In conclusion, replacing date pits up to 20% of concentrate feed in Ardi goat diets did not show adverse effects on nutrients digestibility and animal growth performance.
Green synthesis of silver nanoparticle using Euphorbia hirta L and their antifungal activities

Development of biologically inspired experimental processes for the synthesis of nanoparticles is evolving into an important branch of nanotechnology. Metallic nanoparticles are traditionally synthesized by wet chemical synthesis techniques where the chemicals used are quite often toxic and flammable. The present study deals with cost effective and environment friendly given synthesis from 1mM AgNo3 solution through the leaf extract of Euphorbia hirta L, as reducing as well as capping agent. Nanoparticles were characterized using UV-VIS absorption spectroscopy’s. Green synthesized silver nanoparticles showed the antifungal activity against the Candida albicans, C.kefyr, A.niger.
Patterns of increasing β-agonist use and the risk of fatal or near-fatal asthma

Patterns of increasing β-agonist use and the risk of fatal or near-fatal asthma. ERS Journals Ltd 1994. ABSTRACT: The association between the use of inhaled β-agonists by metereddose inhaler and the risk of fatal or near-fatal asthma has been demonstrated. It shows that asthmatics who use one canister of β-agonist per month more than the number used by other similar asthmatics have twice the risk of fatal or near-fatal asthma. The present investigation assesses the magnitude of this excess risk when an asthmatic increases his/her own monthly use of inhaled β-agonists over time. From a previous nested case-control study of 129 deaths and near-deaths from asthma (cases) and 655 controls from a cohort of 12,301 asthmatics, the subset using at least 12 inhalers during the 12 month study period was identified (97 cases and 258 controls). A profile score, ranging 0–11, was formed to quantify the patterns of β-agonist use over time for each subject, covering the entire spectrum extending from decreasing to increasing use. The relative risk was 15.2 (95% confidence interval (CI) 2.4–96.2) per unit increase of the profile score in subjects with a pattern of increasing β-agonist use (profile score of 6.5 or more), but this relative risk was only 1.5 (95% CI 0.8–2.6) per unit when the profile score was less than 6.5 (non-increasing use). This relative risk was independent of the risk associated with the total quantity of β-agonist use in the 12 month period, which remained around 1.6 (95% CI 1.3–2.0) per inhaler per month. We conclude that above and beyond the quantity of β-agonist used during a one year period, a pattern of increasing use of β-agonist inhalers over that period is a major predictive factor of unfavourable outcomes in asthma. Any trend, over a six month span, of a doubling in the monthly use of β-agonists, or, alternatively, of an increase by one canister in this monthly use, should be regarded as a serious warning sign of an impending life-threatening attack of asthma. Eur Respir J., 1994, 1602–1609. *Dept of Epidemiology and Biostatistics and the Pharmacoepidemiology Research Unit, and †Dept of Medicine, Montreal General Hospital, McGill University, Montreal, Quebec, Canada.
DETECTION OF HELICOBACTER PYLORI IN ATHEROMA OF ISCHAEMIC HEART DISEASES PATIENTS IN THE SOUTH OF IRAQ BY PCR TECHNIQUE

Ischaemic heart disease (IHD) or coronary heart disease (CHD), It is the end result of the accumulation of atheromatous plaques within the walls of arteries that supply the myocardium; Recent study confirmed identification of H. pylori deoxyribonucleic acid (DNA) in atherosclerotic plaques of patients with severe coronary artery disease, which supports the hypothesis that H. pylori infection may influence the development of atherosclerosis. The study aimed to detect presence of H. pylori DNA in the atheroma or intima of 50 subjects (which were divided into two sub groups: persons with IHD and persons without IHD) by PCR technique, the study showed that 3% of persons with IHD and 6% of persons without IHD had positive results and 4% (from all subjects) of study, without regard to group type, had positive results.
Study of structural, morphological and optical properties of nanostructured Zirconium doped V2O5 thin films

Thin films of zirconium doped vanadium pentoxide with different Zr-doping levels (in steps of 0.1mM of Zr) were deposited on glass substrates by a home built spray pyrolysis system. The effect of Zr doping on the structural, morphological and optical characteristics were carried out. X – ray diffraction (XRD) patterns revealed that prepared films were polycrystalline in nature, having an orthorhombic crystal structure. Annealing effect improved the crystallinity of the films. The crystallite size of the films was found to increase after annealing. From FESEM images, the flower shaped structure was observed in the annealed Zr doped V2O5 film. The band gap energy of as deposited films varied with Zr doping.
Timely kinetics of N-terminal pro B-type natriuretic peptide (NT-proBNT) release in acute coronary syndromes

It has been found recently that BNP and NT-proBNP provide independent prognostic information in patients with acute coronary syndromes (ACS). However, little data are available on the time course of NT-proBNP levels in relation to onset of symptoms. We included 765 patients (236 females, aged 64±11 years) with an ACS (STEMI 42%, NSTEMI 41%, UAP 17%) who were referred for coronary angiography. NT-proBNP was assessed on admission and the next day. NT-proBNP values were related to the time duration from the onset of symptoms until blood drawing with lowest values within 3 hours and highest values 24-36 hours after the onset of symptoms (147 (64-436) pg/ml and 1099 (293-3795) pg/ml respectively, p<0.001). Highest values for NT-proBNP on admission were found in patients with NSTEMI compared to patients with STEMI and UAP (912 (310-2258) pg/ml) vs. 262 (85-1282) pg/ml) vs. 182 (74-410) pg/ml; p<0.001), but no difference was found between STEMI and NSTEMI the day after admission (1325 (532-2974) pg/ml vs. 1169 (555-3413) pg/ml; p=0.676). In contrast, NT-proBNP values remained unchanged in UAP (182 (74-410) pg/ml) vs.171 (53-474) pg/ml). The time interval from the onset of symptoms to first blood collection is an important determinant for NT-proBNP values on admission in patients with an ACS and needs to be considered in clinical practice.
Correlation of serum calcium levels with infarct size and severity of stroke using National Institute of Health Stroke Scale in patients with acute ischemic stroke

Background: Normal cerebral membrane integration is important to maintain the cellular calcium homeostasis. Recent studies have suggested that elevated serum calcium levels at presentation correlates well with the infarct size and severity of stroke. Methods: A total of 73 patients with acute ischemic stroke satisfying inclusion and exclusion criteria were included in the study from November 1 2017 to April 3
The Politics of Private Sector Investment in Local Economic Development: Local Governance and Regulatory Frameworks in Gurage Zone, Ethiopia

Private investment is one of the prominent approaches to local economic development. The focus of this study is the exploration of the political elements of private investment in local economic development activities in the backgrounds of local governance. A combination of quantitative and qualitative research methods challenged the idea that private investment, considered economically, contributes to local economic development, an assumption that isolates private investment from the surrounding environments. Therefore, the study found out that private investment in Gurage Zone has been showing an inconsistent trend in terms of its contribution to land development, employment creation, and capital generation. This inconsistency is reflective of the nature of private investment which is a depoliticized, delocalized, and de-bureaucratized program highly isolated from the local realities. This again is related to the detrimental effect of local governance structure which is fragmented, asymmetrical, poorly structured, and de-contextualized, thereby creating weak-bureaucratic services, inefficient partnership, and poorly structured governance platforms. Thus, the study concludes that private investment in Gurage zone is being restrained because of its isolation from the local realities, political imperatives, bureaucratic networks, and resource contexts, supposed to be controlled by the local governments.
Effect of a chitin synthesis inhibitor and a waste product on embryogenesis of Musca domestica

The change in the amounts of DNA, RNA and total protein content (quantitative and qualitative) during embryogenesis of normal and treated Musca domestica eggs (with Lufenuron and waste product) were investigated. DNA content increased gradually reaching its maximum level (2.2μg/ 10 mg DNA) at 7 hrs postoviposition (late embryogenesis). However ,RNA content and total protein decreased gradually reaching their minimum levels (5.3μg/10mgRNA, 1.17mgprotein/10mg egg) at 7 hrs postoviposition ( late embryogenesis). Treatment of Musca domestica eggs with a chitin synthesis inhibitor (Lufenuron) and a waste product from rice straw resulted in a significant decrease DNA and RNA content throughout embryogenesis (0-7hr post oviposition). The treatment also resulted in a significant decrease in total protein of waste product treated eggs compared with the control except at 0hr old eggs (early embryogenesis). Treatment with Lufenuron resulted in a significant increase of total protein in treated eggs compared with the control at 0hr old eggs and 7hrs old eggs (late embryogenesis). However the protein content decreased (p>0.05) in Lufenuron treated eggs to a level similar to that of control at 1, 3, 5 hrs postoviposition( cleavage, gastrulation and organogenesis). The protein profile of normal and treated eggs at different time intervals (0 , 1, 3 , 5 and 7 hrs) during embryogenesis was evaluated to explain their mode of action. A total of 6 -13 protein bands with molecular weight of 5 -120 kilodaltons (KDa) were separated by electrophoresis during normal embryogenesis of Musca domestica . Treatment of Musca domestica eggs with Lufenuron resulted in separation of 9 – 11 protein bands with molecular weight of 25 -150 KDa. Treatment of Musca domestica eggs with waste product resulted in separation of 13 -16 protein bands with molecular weight of 10-200 KDa. The appearance and disappearance of certain protein fractions by application of these compounds may explain their ovicidal activity and disorders occurred during embryogenesis. [Noha A.Guneidy, Dalia A.M.Salem, Nadia Helmy, Wafaa A. Radwan, Reda, F.A. Bakr and Shimaa Salah Effect of a chitin synthesis inhibitor and a waste product on embryogenesis of Musca domestica]. Journal of American Science 2011; 7(12):704-712]. (ISSN: 1545-1003). http://www.americanscience. org.