Miracle-dz/UniFAR-FTUs huggingface dataset:
Acyl-Substituted Dermaseptin S4 Derivatives with Improved Bactericidal Properties, Including on Oral Microﬂora (cid:1)

The 15-mer dermaseptin S4 derivative S4(1–15) was recently shown to exhibit potent activity against oral pathogens associated with caries and periodontitis. Here, we investigated possible modes for improving the peptide’s properties through systematic replacement of an N-terminal amino acid(s) with various fatty acids that modulate the peptide’s hydrophobicity and/or charge. Deletion of 1 to 3 residues led to progressive loss of potency as assessed by MIC experiments performed on four test bacteria. Replacing the deleted amino acids with fatty acids most often resulted in potency recovery or improvement, as evidenced by lower MICs and faster bactericidal kinetics in culture media. Best results were obtained after replacement of the N-terminal dipeptide alanine-leucine with heptanoic (C 7 ) or aminododecanoic (NC 12 ) acid. Circular dichroism analysis correlated antibacterial properties to the peptide’s secondary structure. MIC experiments and confocal laser scanning microscopy results indicated that C 7 -S4(3–15) and NC 12 -S4(3–15) were bactericidal to various oral pathogens, including those which are immobilized in a bioﬁlm. C 7 -S4(3–15) performed similarly to or better than (depending on growth medium) IB-367, a peptide assessed in clinical trials for treatment of oral mucositis, reducing CFU counts by >3 log units within 2 min of incubation. Collectively, the data indicate that substitution of fatty acids for amino acids may be a useful strategy in revealing improved derivatives of known antimicrobial peptides and suggest the suitability of such compounds for controlling pathogens associated with oral diseases.
Comparative patterns of dung beetle (Coleoptera: Scarabaeidae) diversity in native fescue grassland and wooded habitats in the Cypress Hills, Alberta, Canada

Abstract Dung beetles (Coleoptera: Scarabaeidae (Aphodiinae, Scarabaeinae) and some Geotrupidae) provide important ecosystem services on pastures by disrupting and burying deposits of cattle dung. The extent of these services is influenced by the number of individuals and species present, which may differ with habitat type. In the present study, we compared dung beetle assemblages in a mosaic of open grassland and wooded habitats on native fescue pastures in the Cypress Hills of southern Alberta, Canada. Using pitfall traps baited with cattle dung and operated from spring through autumn for two years at each of the two sites, we collected 4944 individuals representing 14 dung beetle species. More individuals and species were recovered in grassland habitat, which was dominated by nonnative species associated with cattle dung. Wooded habitat was dominated by a native species associated with deer dung. Dwellers (species that develop within the dung deposit) comprised 93% of the beetles recovered during the study. Significant variation in annual beetle counts in the two habitats highlights the value of studies conducted over multiple years. These results emphasise the importance of habitat diversity and interspecific habitat preference in structuring dung beetle assemblages on fescue grasslands, which are among the most threatened ecosystems in Canada.
Vegetarian vs Mediterranean diet for prevention of cardiovascular disease

1. Chapter 1: Introduction 2. Chapter 2: Cardiovascular disease 2.1. Definition and pathogenesis 2.2. Epidemiology 2.3. Risk factors and prevention 3. Chapter 3: Nutrition and cardiovascular disease 4.1. Characteristics of a heart-healthy diet 4. Chapter 4: Mediterranean diet 4.1. Characteristics 4.2. Mediterranean diet and cardiovascular health 5. Chapter 5: Vegetarian diet 4.1. Characteristics 4.2. Vegetarian diet and cardiovascular health 6. Chapter 6: Aim of the study 7. Chapter 7: Experimental procedures 7.1. Study design and sample 7.2. Outcomes 7.3. Eligibility criteria 7.4. Intervention diets 7.5. Data collection 7.6. Compliance and acceptability 7.7. Data management 7.8. Laboratory measurements 7.9. Statistical analysis 3
A generalized Allendoerffer-Weil formula and an inequality of the Cohn-Vossen type

In this paper we present a version of the Gauss-Bonnet-Chern formula which applies to arbitrary compact locally convex subsets C of a riemannian manifold M. The classical counterpart is the Allendoerfϊer-Weil formula for riemannian polyhedra [1]. But while the singularities of a polyhedron are separated along submanifolds, we do not have to restrict the set of singularities, in particular, this set can be dense in the boundary of C. An important role is played in our formula by the set Jίc of outer vectors of C, which is a locally lipschitz submanifold of TλM. In fact, the boundary terms appear as integrals over Jfc of an almost everywhere defined differential form, in which enter curvature quantities of M along dC and a generalized second fundamental form of dC which is symmetric and positive semidefinite almost everywhere. In the case of a positive semidefinite curvature operator along dC, the boundary terms can be estimated thus giving a sort of Cohn-Vossen inequality for such sets C. For dimensions not exceeding 6, the assumption on the curvature operator can be replaced by K > 0 along dC. Several corollaries apply to the existence of, and bounds for, the total curvature of complete manifolds of nonnegative curvature.
Young Students' Self-Beliefs about Using Representations in Relation to the Geometry Understanding.

Students’ cognitive performance on any mathematical concept is related with the respective self-beliefs on understanding it and on using strategies in order to overcome cognitive obstacles. The purpose of the present study was to investigate the role of various aspects of apprehension (perceptual, operative and discursive) in geometrical figure understanding and the respective students’ self-beliefs about using representations as a useful tool for understanding geometrical concepts and for solving geometrical tasks. The interest was concentrated on finding the structure and the interrelations between students’ self-concept beliefs, their self-efficacy beliefs about using representations and the geometrical understanding at primary and secondary education. A quantitative study was developed and data were collected from 1086 students in Grade 5 to 8. Confirmatory factor analysis provided support for the invariance of the structure for the geometrical figure understanding across the two ages groups and it affirmed the existence of a coherent model of self-beliefs dimensions about the use of representations for understanding the geometrical concepts, which becomes more stable across the educational levels. There are interesting differences concerning the interrelations among cognitive and noncognitive factors between primary and secondary education.
THE IMPACT OF CAPITAL STRUCTURE ON PROFITABILITY OF ETHIOPIAN CONSTRUCTION COMPANIES: EVIDENCE FROM LARGE TAX PAY ORGANIZATIONS

The choice of fund sources to finance an organization’s operation and investment activities is one of the major activities organization managers have to decide. This decision of managers in financing their firm’s operation and investment could involve; issuance of debt, raising of new capital through issuance of additional shares of equity, or retaining of capital from earnings generated from operations; and selection from among them largely depend on the effect they have on the organizations’ profitability. The main essence of the study is to examine the impact of capital structure on Ethiopian Construction Companies Profitability, evidence from large tax pay organizations. This thesis shade a new light for Ethiopian capital structure studies and the importance of giving a thorough thought for different maturity level of debt in studies of capital structure. The data collected for this paper is limited on ten years financial statement of selected construction Companies. This is because there is a problem to get accurate financial information and also it is difficulty on data collection from companies itself. So, the researcher wants to study on this sector by sampling ten large tax pay construction companies to have the actual data and to ease of generalization based on their availability of data for the researcher. The researcher found quantitative research approach appropriate. This is because quantitative approach is an inquiry that grounded in the assumption that features of social environment constitute an objective reality that is relatively constant across time and setting. Accordingly the result of the study shows that Return on equity and short term debt ratio have statically significant positive effect on the profitability of construction companies in Ethiopia. debt on Ethiopian Construction Companies’ Profitability.
Compressive sensing in FPGA and microcontroller

— This paper show the hardware implementation of the technique known as Compressive Sensing (CS). CS work develops in a sparse space (dense few). We used to obtain sparse signals Discrete Fourier Transform (DFT), Discrete Cosine Transform (DCT), and Discrete Wavelet Transform (DWT). We demostred that speech, electromyography and electrocardiogram signals can be reconstructed from few samples (projection). These projections were physically transmitted to a computer for reconstruction using L1 magic and demostrate that CS projections obtained were correct. The implementation CS showed relevant results, increase in speed and developing new communications. The implementation was performed in a Field Programmable Gate Array (FPGA) SPARTAN 3E and 18F4550 microcontroller. The results showed that is possible the reconstruct signals, breaking Shannon and Nyquist’s theory. Furthermore, we concluded that the FPGA implementation is faster and allows higher compression rates than the microcontroller. Finally, we showed using minimization L 1 that DWT, presents better results in sparse conversion.
Alien Visitation, Extra-Terrestrial Life, and Paranormal Beliefs

—The present paper investigated the nature and structure of extra- terrestrial beliefs. Respondents completed a booklet containing items measuring belief in extra-terrestrial life, alien visitation, and paranormal belief (Revised Paranormal Belief Scale, R-PBS; and the Australian Sheep Goat Scale, ASGS). Responses were analyzed using principal component analysis (PCA), and a three-factor structure emerged: alien visitation, belief in extraterrestrial life, and the search for extra-terrestrials. Further analysis revealed that males scored higher than females on belief in extra-terrestrial life and the search for extra-terrestrial life. No difference was observed for alien visi- tation. Correlational analysis found signi ﬁ cant positive associations between each of the extra-terrestrial life factors and alien visitation. In addition to this, the extra-terrestrial life factors and alien visitation were found to correlate with overall paranormal belief (ASGS), and the two factors of the R-PBS (Traditional Paranormal Belief and New Age Philosophy). Alien Visitation was more strongly correlated with the paranormal belief measures than the extra-terrestrial belief factors; these were found to be negatively correlated with the paranormal belief measures when Alien Visitation was controlled for. These ﬁ ndings indicate that only more extreme Alien Visitation beliefs were associated with belief in the paranormal.
Topological Network Properties of the European Football Loan System

Research Question : Following a network perspective, we present footballs European loan system as an economic network and aim to answer the following questions; (i) what is the structure of the network? and, (ii) what are the topological properties of the network? Research Methods: Using data on the top-5 European leagues in European football 8139 loan transactions between 31/12/2009 – 22/12/2017 were analysed using social network analysis. Results and Findings: The results show that the loan system is embedded in ongoing structural relationships across Europe, more so in the Italian Serie A than other European leagues investigated. Additionally, our findings indicate that several elite clubs are extracting value from the loan system, while others are value creators. Implications: The implications of this research are fourfold: recommendations for executive-level professionals in the football industry and how to maximise the structure of the system; considerations for UEFA and FIFA policy around regulations applied to loan systems; application of economic network theory to the trading (loan) system in European football; and recommendations for future academic research.
Modeling Surface Sensible Heat Flux Using Surface Radiative Temperatures in a Simple Urban Area

Abstract Sensible heat fluxes over a light industrial area in Vancouver, British Columbia, Canada, are analyzed from observed tower fluxes and modeled using a bulk heat transfer approach. The bulk transfer models are initialized using remotely sensed surface temperatures from both airborne and ground-based observing platforms. The remotely sensed surface temperature, in conjunction with a surface database, is used to create area-weighted temperature estimates representative of the complete urban surface. Sensitivity analyses of the various surface temperature estimates are performed. Estimates of kB−1, the ratio of roughness length of momentum to heat, for this area are in general agreement with theoretical estimates for bluff-rough surfaces and are larger than those documented for vegetated and agricultural surfaces. Back-calculated values do vary depending on the method used to determine surface temperature but vary more with the time of day. Empirical relations derived previously for vegetated surfaces.
A Short Review on Cryoprotectants for 3D Protein Structure Analysis

: The three-dimensional structure of protein is determined by analyzing diffraction data collected using X-ray beams. However, X-ray beam can damage protein crystals during data collection, lowering the quality of the crystal data. A way to prevent such damage is by treating protein crystals with cryoprotectants. The cryoprotectant stabilizes the protein crystal and prevents lowering the quality of the diffraction data. Many kinds of cryoprotectants are commercially available, and various treatment methods have also been reported. However, incorrect selection or treatment of such cryoprotectants may lead to deterioration of crystal diffraction data when using X-ray beams.
Quantum Leap: From Dirac and Feynman, Across the Universe, to Human Body and Mind

This is a unique 21st-century monograph that reveals a basic, yet deep understanding of the universe, as well as the human mind and body — all from the perspective of quantum mechanics and quantum field theory.This book starts with both non-mathematical and mathematical preliminaries. It presents the basics of both non-relativistic and relativistic quantum mechanics, and introduces Feynman path integrals and their application to quantum fields and string theory, as well as some non-quantum applications. It then describes the quantum universe in the form of loop quantum gravity and quantum cosmology. Lastly, the book turns to the human body and mind, applying quantum theory to electro-muscular stimulation and consciousness.It can be used as a graduate (or advanced undergraduate) textbook for a two-semester course in quantum physics and its modern applications. Some parts of the book can also be used by engineers, biologists, psychologists and computer scientists, as well as applied mathematicians, both in industry and academia.
The Influence of Knowledge and Attitude as Consumer Behavior on Product Purchase Interest on Lazada E-Commerce

This research was conducted to determine the effect of knowledge and attitudes as consumer behavior on product purchase intention on Lazada e-commerce. The population in this study are all consumers who are all people who will make purchases at e-commerce Lazada in 2021. The sample in this study using the Lemeshow formula shows as many as 100 respondents in the fishing mania community in South Sumatra with the sampling technique in this study and using a non-probability sampling method. The results of the multiple linear analysis show that knowledge as consumer behavior has a positive and significant effect on product buying interest on Lazada e-commerce. Attitudes as consumer behavior have a positive and significant effect on product buying interest in Lazada e-commerce. In the knowledge variable, Lazada needs to fix it in the form of a direct warning to the seller, who is considered problematic in presenting the information. In addition, the consumer attitude variable shows that they are not completely satisfied with the information on the products sold on Lazada. Therefore, Lazada must be even more active in supervising the products that resellers will sell.
Water Use Efficiency, Yield, Available Nutrient and Economics of Greengram (Vigna radiata (L.) Wilczek) as Influenced by Plant Density and Irrigation Management

A field experiment was carried out during the summer season of the year 2013 at SAUD, Sardarkrushinagar to study the “water use efficiency, yield, available nutrients and economics of green gram (Vigna radiata (L.) wilczek) as influenced by plant density and irrigation management”. The highest water use efficiency (3.28 kg ha−1mm) observed under application of irrigation at critical growth stages, while in case of spacing, it was recorded highest (2.56 kg ha−1mm) under spacing of 30 x 10 cm. The seed yield (1107 kg ha−1) and stover yield (1970) were observed significantly higher under the 1.0 IW:CPE ratio followed by 0.8 IW:CPE ratio. In case of spacing 30 cm x 10 cm gave significantly higher grain yield of green gram. Same trend was observed in case of stover yield. An interaction effect between irrigation schedule and spacing levels on seed yield and net realization were found significantly higher under 1.0 IW/CPE ratio with 30 x 10 cm spacing (I3S1) followed by treatment combination 0.8 IW/CPE ratio with 30 x 10 cm spacing. Protein content and available nutrients failed to exert it's significant effect due to irrigation schedule, spacing and also their interaction.
Structure change of pyrochlore Sm2Ti2O7 at high pressures

Structural evolution of pyrochlore titanate Sm2Ti2O7 at high pressures was investigated by in situ Raman and x-ray diffraction methods. An intermediate phase was found at high pressures. The structure is a distorted pyrochlore, where anions are disordered after 40GPa while the cations are still somewhat ordered up to 51GPa. When the pyrochlore structure is severely distorted by external pressure, it transforms completely to an amorphous phase quenchable to room conditions.
Water relations of lettuce seed thermoinhibition. II. Ethylene and endosperm effects on base water potential

Abstract A water relations (hydrotime) model was employed to characterize the responses of lettuce (Lactuca sativa L.) seed germination to temperature, water potential (ψ), endosperm disruption, and the ethylene precursor 1-aminocyclopropane-1-carboxylic acid (ACC). The base water potentials (ψb), standard deviations of base water potential and hydrotime constants (θH) estimated by the model were used to predict the germination rates at reduced ψ and supraoptimal temperatures in the presence or absence of ACC. The distribution of ψb values among seeds in the population (ψb(g)) increased (became more positive) as the imbibition temperature increased, indicating a greater sensitivity of seeds to reduced ψ at thermoinhibitory temperatures. Slitting the seeds at the cotyledonary end to disrupt the integrity of the endosperm extended the high temperature range for germination and maintained lower ψb(g) distributions compared with intact seeds as temperature increased. ACC (10 mm) in the imbibition solution raised the upper temperature limit for germination by about 2°C, and also lowered ψb(g) values by 0.1 to 0.2 MPa. The effect of ACC on ψb(g) was more pronounced at higher imbibition temperatures and in slit seeds. ACC (via conversion to ethylene) extends the high temperature limit for lettuce seed germination by acting in the embryo to maintain a lower ψ threshold for the initiation of growth as temperature increases. Evidence from other species as well suggests that this may be a general mechanism for the action of ethylene in promoting seed germination.
Clinicopathological Profile of Patients with Chronic Leukaemia

Leukaemias are the malignancies arising from unregulated clonal proliferation of haematopoietic stem cells. The present work is an attempt to study the frequency of chronic leukaemia, to analyse and classify and to correlate the clinicopathological findings in patients with chronic leukaemia. The present study included 50 cases over a period of two and half years. Taking into consideration detailed clinical history and physical examination; we performed peripheral smear examination after staining with Leishman stain. We found 37 cases of CML and 13 cases of CLL. monoclonal antibodies that define a unique antigen associated with prolymphocytic lymphoma and are effectively internalized after binding to the cell surface antigen.
Free surface shear flow model for bow vortices phenomena

Experiments by Sharma, Eggers and others in the Insti tut fur SChi,ffbau, Hamburg showed that when a horizontal circular cylinder is towed semisubmerged at a uniform speed, there exists a free surface shear layer ahead of the cylinder. The deceleration of the fluid particles in the free surface boundary layer gives rise to vortices before the body and a free surface separation point which separates the vortex zone Dear the body from rest of the flow. These observations provided an explanation to the origin of the phenomenon of bowwave-breaking which occurs as vortical motion ahead of the ships with usually blunt bows and extends all around the hull commonly called as necklace vortex. In the present study an attempt is made to formulate a shear flow-model for the free surface flow ahead of the cylinder in the framework of boundary layer theory in order to provide a theoretical analysis to the experimental observations. The vorticity generated due to viscous forces at the boundary is assumed to be concentra ted in a thin free surface boundary layer while the flow underneath this layer is assumed to be potential. Karman-Pohlhausen method is used to solve the two dimensional boundary layer equations in curvilinear coordinates. The boundary layer profile is assumed to be a cubic satisfying stress and velocity conditions at the boundary. The velocity defect in tha boul~ary layer is assumed to be relatively small in order to simplify the problem. The free surface configuration which needed to be prescribed for the computations is substituted from that of constant pressure surface of the double body flow without satisfying any kinematic condition. flqw The computatlons show that the free surface/slows down relative to the potential flow and the velocity defect increases as the distance from the cylinder decreases. The free surface velocitybecomes negative resulting in backflow ahead of the cylinder as observed in the experiment. This however occurs at exceedingly close distances from the cylinder. The computation of the boundary layer profile shows a regular growth of shear as the body is approached. The free surface separation point moves away from the cylinder as the Froude number i5 increased which is also in agreement with the experimentalobservations. The occurrence of the free surface separation point at exceedingly close distances from the body which is against the experimental observations stresses the need for an improvement in the analysis. An attempt was made to obtain free surface and the potential flow velocity components incorporating surface