Miracle-dz/UniFAR-FTUs huggingface dataset:
A Study on the Expression of Heat Shock Protein Genes in the Human Periodontal Ligament Fibroblasts.

熱ショック蛋白質 (hsp) と歯周炎との関わりを探る第一歩として, ヒト歯根膜由来線維芽細胞PDL) におけるhsp遺伝子発現をRT-PCR法を用いて検討した。 (Hsp70, hsp60遺伝子ともに無刺激下でもPDLにおける発現が確認された。 また, hsp70は, 42℃, 1時間のheatshock処理およびActinoobacillus actinomycetemcomitans, E. coliの破砕液の24時間刺激により, その発現の増強が認められたが, Streptococcus sanguis, Lactobacillus caseiの破砕液刺激では変化は認められなかった。 また, hsp60については上記の刺激によっても発現の増強は認められなかった。 今回の結果から, 細菌破砕液がhsp70発現を誘導し得るストレスとなり, また歯周病原性細菌による感染の際に歯周組織のhsp70の発現量が増大する可能性が推察された。 本論文の要旨は, 第37回秋季日本歯周病学会 (1994年10月6日) において発表した。
Effect of packaging materials and storage temperature on quality of some local fruit juices

Recent processed orange, mango and guava juices packed in TetraPack, aluminum, foil plastic and glass containers were collected from the local market and evaluated chemically and microbiologically periodically every two months, during 12 months storage at refrigeration temperature (4oC) and room temperature (22-27oC). Results showed that total titrabble acidity (TTA) of the juices decreased in a descending order as follow, aluminum packages, Tetra Pack packages, plastic bottles and glass bottles for juices stored at 4 ̊C and room temperature . however non-enzymatic browning increased in an ascending order as follows Tetra Pack, aluminum, plastic bottles and glass bottles up to 6 months then started to decrease in the same order. The flavanones content was only affected by the time of storage while the effect of storage temperature and packaging material was quite slight. The material which presented the lowest retention of both ascorbic acid and b-carotene was found to be in glass followed by plastic containers. The aluminum packages presented a poor retention of ascorbic acid. Fruit juice stored at the refrigeration temperature (4oC) retained the desired quality attributes in juices better than juices stored at room temperature (22-27oC). Glass bottles gave greater protection against degradation of the chemical attributes of the fruit juices
Religious orientation and psychological well-being among Spanish undergraduates

Abstract This paper analyzes the relationship between intrinsic/extrinsic/quest religious orientation and psychological well-being in a sample of 180 Spanish undergraduates, 138 women (76.7%) and 42 men (23.3%), aged 18-55, M = 22.91, SD = 6.71. Spanish adaptations of the Batson and Ventis' Religious Orientation Scale and the Ryff's Psychological Well-Being Scales were used to this aim. The results of a multiple regression analysis showed (1) a positive relationship between the intrinsic orientation and the psychological well-being measures except for Autonomy, (2) a negative relationship between the extrinsic orientation and Autonomy, and (3) a negative relationship between the quest orientation, Self-acceptance and Purpose in life. The results are discussed in the light of previous researches.
The nurse teacher. Construction of a new professional identity

Objective. To represent how a new identity is being constructed by nurses initiating their activities as teachers. Methodology. In 2010, a descriptive-interpretative qualitative research was conducted of four cases of nurse teachers from Nursing Schools. Aspects of teacher identity and management of critical incidents in the classroom were reviewed. The information was obtained through a structured survey and the data underwent analysis of contents. Results. The nurses surveyed state that the teaching exercise is a culmination stage of clinical nursing. Teaching confers them stability in their professional life; however, they report that the complexity of the educational practice poses a big challenge. They feel responsible for the formation of future nursing professionals. In spite of defining themselves as constructivists in the way of teaching, they are governed by a technical conception on the way of approaching the educational practice. They attribute the critical incidents to which they are exposed to the types of students entering the universities; these turn out uncomfortable and do not feel responsible for their development. These incidents are lessons to better face similar situations in the future. Conclusion. The nurses participating in this study are facing their new role as teachers of human resource, seeking to construct a new identity different from what they had when working in direct care of individuals.
CLINICAL EFFICACY OF NEBULIZED BUDESONIDE IN ACUTE EXACERBATION OF COPD

INTRODUCTION: Systemic corticosteroids are routinely used for the treatment of acute exacerbation of COPD (AECOPD). Preliminary studies have demonstrated that nebulised budesonide to be as efficacious as parental steroids in AECOPD. OBJECTIVES: To evaluate the clinical efficacy of nebulised budesonide with in AECOPD in comparison with parental steroids. MATERIALS AND METHODS: Patient’s with AECOPD were included in the study and divided into two groups randomly. Control group who were given parental steroids and Study group received budesonide by nebulisation (2 mg every 12 hrly) for 5 days. These patients were assessed every 12 hrly from H0 to H72, day 5 and at discharge. The outcome variables studied were FVC, FEV1, PEFR, dyspnea score, spO2 and SGRQ score. Both groups received standard treatment i.e. oxygen, salbutamol plus ipratropium by nebulisation and parental antibiotics during study period. RESULTS: A total of 125 patients were included in the study: 65 in study group and 60 in control group. The baseline FEV1, FVC and PEFR were comparable in both groups. The mean improvement in FEV1, FVC and PEFR after 24 hrs, 72 hrs and day 5 were non-significantly increased in both the groups. Similarly, improvements in oxygen saturation and dyspnea grade at day 5 showed no significance between the two groups. Patients in the study group showed better improvement in SGRQ score as compared to control group. Mean duration of hospitalization was less in study group as compared to control group. CONCLUSION: Nebulised budesonide was equally as efficacious as parental steroids in AECOPD. Nebulised budesonide group had reduced duration of hospitalization and showed better improvement in SGRQ score as compared to control group.
The Emotional Brain: The Mysterious Underpinnings of Emotional Life

What happens in our brains to make us feel fear, love, hate, anger, joy? do we control our emotions, or do they control us? Do animals have emotions? How can traumatic experiences in early childhood influence adult behavior, even though we have no conscious memory of them? In The Emotional Brain, Joseph LeDoux investigates the origins of human emotions and explains that many exist as part of complex neural systems that evolved to enable us to survive. Unlike conscious feelings, emotions originate in the brain at a much deeper level, says LeDoux, a leading authority in the field of neural science and one of the principal researchers profiled in Daniel Goleman's Emotional Intelligence. In this provocative book, LeDoux explores the underlying brain mechanisms responsible for our emotions, mechanisms that are only now being revealed. The Emotional Brain presents some fascinating findings about our familiar yet little understood emotions. For example, our brains can detect danger before we even experience the feeling of being afraid. The brain also begins to initiate physical responses (heart palpitations, sweaty palms, muscle tension) before we become aware of an associated feeling of fear. Conscious feelings, says LeDoux, are somewhat irrelevant to the way the emotional brain works. He points out that emotional responses are hard-wired into the brain's circuitry, but the things that make us emotional are learned through experience. And this may be the key to understanding, even changing, our emotional makeup. Many common psychiatric problems - such as phobias or posttraumatic stress disorder - involve malfunctions in the way emotion systems learn and remember. Understanding how thesemechanisms normally work will have important consequences for how we view ourselves and how we treat emotional disorders.
The influence of land use and land cover change on landslide susceptibility: a case study in Zhushan Town, Xuan'en County (Hubei, China)

Abstract. Land use and land cover change can increase or decrease landslide susceptibility (LS) in the mountainous areas. In the hilly and mountainous part of southwestern China, land use and land cover change (LUCC) has taken place in the last decades due to infrastructure development and rapid economic activities. This development and activities can worsen the slope susceptible to sliding due to mostly the cutting of slopes. This study, taking Zhushan Town, Xuan'en County, as the study area, aims to evaluate the influence of land use and land cover change on landslide susceptibility at a regional scale. Spatial distribution of landslides was determined in terms of visual interpretation of aerial photographs and remote sensing images, supported by field surveys. Two types of land use and land cover (LUC) maps, with a time interval covering 21 years (1992–2013), were prepared: the first was obtained by the neural net classification of images acquired in 1992 and the second by the object-oriented classification of images in 2002 and 2013. Landslide-susceptible areas were analyzed using the logistic regression model (LRM) in which six influencing factors were chosen as the landslide susceptibility indices. In addition, the hydrologic analysis method was applied to optimize the partitioning of the terrain. The results indicated that the LUCC in the region was mainly the transformation from the grassland and arable land to the forest land, which is increased by 34.3 %. An increase of 1.9 % is shown in the area where human engineering activities concentrate. The comparison of landslide susceptibility maps among different periods revealed that human engineering activities were the most important factor in increasing LS in this region. Such results emphasize the requirement of a reasonable land use planning activity process.
Women leaders in the political field in Scotland: A socio-historical approach to the emergence of leaders

Drawing on a contextualised case, we present a specific approach to leadership studies that brings together history, sociology and politics. We start with the following event. In August 2015, the election of Kezia Dugdale as leader of the Labour Party meant that, for the first time the leaders of the three main political parties in the Scottish Parliament were women. We approach the study of this significant leadership event, first, through a critique of aspects of leadership studies as a field. We next consider the potential for socio-historical approaches in understanding this event. Then, as a contextualised example of this alternative approach to studying leadership, we apply Bourdieu’s theoretical concepts – in particular the political field – in order to historicise the conditions of possibility of this event. Finally, we consider issues of power and gender in relation to how the leaders position themselves in relation to their parties and to each other within the political field. In so doing, we contribute to critical leadership studies by developing and demonstrating a socio-historical approach that can help us to identify processes of organisation and change in relation to the emergence of leaders.
Preschool children's conceptions of moral and social rules.

SMETANA, JUDITH G. Preschool Children's Conceptions of Moral and Social Rules. CHILD DEVELOPMENT, 1981, 52, 13883-1336. This study examined preschool children's conceptions of moral and social-conventional rules. 44 children between the ages of 2-6 and 4-9 were divided into 2 groups of 21 and 23 children according to age (X = 3-3, 4-2). Children made judgments concerning the seriousness, rule contingency, rule relativism, and amount of deserved punishment for 10 (depicted) moral and conventional preschool transgressions. Analyses of variance with age and sex as between-group factors and domain as the within-group factor indicated that, constant across both sexes and the ages studied, children evaluated moral transgressions as more serious offenses and as more deserving of punishment than conventional transgressions. Moreover, moral events were less likely than conventional events to be regarded as contingent on the presence of a rule and relative to the social context. Test-retest reliability of the ratings of the seriousness of transgressions was . 66 over a 2-3 week period. The findings were discussed in relation to the developmental differentiation model and the distinct conceptual domain approach.
Vascular endothelial growth factor expression and regulation of murine collagen-induced arthritis

Objective The expression and function of the angiogenic factor,vascular endothelial growth factor (VEGF) during the evolution of type Ⅱ collagen induced arthritis (CIA) were examined.Methods Passive immunization was taken to induce CIA and arthritis index was evaluated.The VEGF and vWF proteins were measured by ELISA.The VEGF and vWF were visualized by immunohistochemistry.The expression of VEGF mRNA was analyzed by RT PCR and Southern blotting.Results The VEGF and vWF levels reached a maximum on day 4 after the onset of arthritis and then gradually declined,neovascularization thus correlated temporally with both VEGF expression and footpad swelling.The VEGF transcripts,especially the 279 bp and 304 bp forms,were constitutively expressied in joint tissues.Conclusion The VEGF plays a crucial role during an early stage of arthritis development,affecting both neovascularization and the progression of experimentally induced synovitis.
Student-Instructor Out-of-Class Communication: A Media Multiplexity Approach

Student-Instructor Out-of-Class Communication: A Media Multiplexity Approach Cathlin V. Clark-Gordon The present set of studies examined media multiplexity theory (MMT; Haythornthwaite, 2005) in the context of student-instructor out-of-class communication (OCC) in two samples: undergraduate and graduate students. It was predicted that student-instructor tie strength (closeness) would lead to a greater number of modes used for OCC, and subsequently, the number of modes used for OCC would predict positive classroom outcomes, including communication satisfaction, cognitive and affective learning, and motivation. It was also predicted that the effect of closeness on the number of modes used for OCC would be moderated by student’s enjoyment of online communication, insofar as it would suppress the amount of modes used to communicate outside the classroom for those students who did not enjoy online communication, or amplify the effects for those students that did enjoy online communication. Results revealed that for undergraduate students, the number of media used to communicate with one’s instructor indirectly impacted their communication satisfaction, affective and cognitive learning, and motivation, through their feelings of the closeness with their instructor, contrary to the hypothesized model. This effect was strengthened for those students who had greater enjoyment of online communication. For graduate, the same pattern of indirect effects emerged, but enjoyment of online communication had no moderating effect in the graduate student sample. Implications for Media Multiplexity Theory (MMT) and viewing the student-instructor relationship as interpersonal are discussed. Because MMT was supported by the present studies, important conclusions on the nature of the student-instructor relationship, and the subsequent effects of their communication patterns are drawn.
Alternatives to consider during cefotaxime shortage

A shortage of intravenous cefotaxime sodium is being reported by the Food and Drug Administration (FDA), as one of the current manufacturers has discontinued production of the cephalosporin antibiotic. Cefotaxime often is used in infants under 2 months of age when a third-generation cephalosporin
"Reduced Mortality Associated with Long-term Postmenopausal Estrogen Therapy."

Objective To compare all-cause and specific-cause mortality rates in women who had or had not used long-term postmenopausal estrogen replacement therapy (ERT). Methods We identified women who used long-term postmenopausal ERT and compared them with a sample of age-matched postmenopausal nonusers. Through linking of these subjects' medical record numbers to various data bases, we examined survivorship and cause of death among estrogen users and nonusers. The risk of death in 232 postmenopausal women who began ERT within 3 years of menopause and used it for at least 5 years was compared with that of 222 age-matched postmenopausal nonusers. In the users, the mean length of estrogen use was 17.1 years. Results Statistically significant reductions in all-cause mortality were found in users compared with nonusers. For death from any cause, the age-adjusted relative risk (RR) and associated 95% confidence interval (CD in estrogen users was 0.54 (0.38–0.76). The reduction in all-cause mortality was largely due to reductions in coronary heart disease (RR 0.40, CI 0.16–1.02) and other cardiovascular disease (RR 0.27, CI 0.10–0.71). Overall cancer mortality was similar in the two groups (RR 0.85, CI 0.46–1.58), although estrogen users had a higher risk of death from breast cancer (RR 1.89, CI 0.43–8.36) and lower risk of death from lung cancer (RR 0.22, CI 0.04–1.15). Conclusion Long-term ERT use is associated with lower all-cause mortality and confers this apparent protection primarily through reduction in cardiovascular disease.
Neuromuscular Diseases of Infancy and Childhood

Sir Charles Symonds is a preeminent neurologist whose career has spanned the 40-year period marking the emergence of neurology as a major specialty. For this reason, if no other, a new book compiling his writings must be regarded as a major publishing event. But in addition, this particular book offers unique values: The contents are the papers the author himself selected as his most important contributions; the writing is exceptionally strong and lucid; and the whole provides a capsule-history not only of the specialty but the leaders who shaped the specialty. Neurologists to whom the papers are well known will be glad to have them gathered together in this form; physicians and students in training will find it a valuable source of basic and varied information. Two features are of particular interest—the "autobiographic introduction" and the brief background sketches introducing the separate papers. The author's developmental years were spent with
Reduction in Serum Bilirubin Concentration Following Administration of Crude Leaf Extract of Viscum album (Mistletoe) in High Salt Fed Rats

Aims: This study was designed to determine the effect of a high salt diet on serum bilirubin concentration and to ascertain the impact of treatment with Viscum album on same. Methodology: Twenty male albino wistar rats weighing 150 200g were used for this study. After seven days of habituation, the animals were randomly divided into four (4) groups of five rats each. Group 1 (NC) served as control and were fed with normal rat pellet and water; group 2(NT) served as the control treated group (administered 150 mg/kg Viscum album orally, in addition to rat pallet and water); group 3 (SF) served as the high salt diet fed group (without treatment), while group 4 (ST) served as the high salt diet fed group, treated orally with 150 mg/kg Viscum album. The feeding regimen lasted for six weeks, after which the animals were sacrificed and blood samples collected for analysis. Results: Mean serum total bilirubin concentration was significantly (p<0.001) higher in the SF group compared to control, NT and ST group. It was also significantly (p<0.001) lower Original Research Article British Journal of Pharmaceutical Research, 4(3): 352-361, 2014 353 in the ST group compared to SF group. Serum conjugated bilirubin concentration was significantly (p<0.001) increased in the SF group compared to NC, NT and ST group. It was also significantly (p<0.001) reduced in the ST group compared to the SF group. Serum unconjugated bilirubin concentration was significantly (p<0.001) increased in the SF group compared to NC, NT and ST group. Serum unconjugated bilirubin concentration was significantly (p<0.01) lower in the ST group compared to SF group. Conclusion: Our results are indicative of the fact that oral administration of Viscum album reduces serum bilirubin concentration in high salt fed animals.
Spontaneous Rupture of Pancreatic Mucinous Cystadenocarcinoma: A Case Report and Review of Literature

The pancreatic cystic lesions are known to be incidentally found up to 10-15% of patients undergoing cross-sectional imaging. And the prevalence of mucinous cystic neoplasm which has malignant potential is known to be up to 25% of all pancreatic cystic neoplasm in South Korea. The symptoms included abdominal pain, palpable mass, weight loss, loss of appetite, jaundice, asymptomatic and etc. However, spontaneous rupture of pancreatic mucinous cystadenocarcinoma (MCAC) is an extremely rare complication. Here we report a case of spontaneous rupture of pancreatic MCAC in a 72-year-old male with review of the literature. To the best of our knowledge, this is the first ruptured case of pancreatic MCAC in male patient. Korean J Pancreatobiliary 2016;21(1):24-28
Being a homeopath. Learning and practice in a homeopathic community

In this In this paper I look at the Romanian homeopathic practice through the conceptual lens of the communities of practice. Through interviews with homeopathic practitioners, I investigate the ways they accumulate and share their specific knowledge. Also, I inquire about some homeopathic practices and concepts, such as the consult and the vital force. Then, I present the way homeopaths combine methods that are specific to their practice with biomedical techniques and procedures in order to obtain a better diagnostic and also how they evaluate the usefulness of homeopathic knowledge in comparison with biomedical knowledge. Although this is a small scale research, it sheds light on the importance of the continuous learning process and knowledge sharing that goes on between homeopathic practitioners.
No more worksheets: a pre-service teacher's look at manipulatives

Kathren Field Barraclough NO MORE WORKSHEETS: A PRE-SERVICE TEACHER'S LOOK AT MANIPULATIVES 2004/05 Dr. Susan Browne Masters of Science in Teaching Collaborative Education The purpose of this study is to explore the use of manipulatives during math. This is done by examining manipulatives in reference to student interest, diverse learners, student response, and student opinions. The study was conducted in an elementary school in the Winslow Township school district located in the Camden County region of South Jersey. All seventeen participants were taken from a collaboratively taught first grade classroom. Collection of data was done through the use of video tape, student journals, tests and my personal observations. Data was triangulated through the examination of multi-sources (video, journals, tests, observations), and themes, scores and interesting remarks were analyzed. In conclusion to the study one unifying pattern was found during the exploration ofmanipulatives was student eagerness. Their eagerness to use and explore manipulatives provided them with the openness to learn thus increasing their knowledge of the subject at hand.