Miracle-dz/UniFAR-FTUs huggingface dataset:
How biography influences research: an autoethnography

Inspired by Professor Yvonne Jewkes’ plenary speech at the 2013 British Society of Criminology conference, this paper focuses on the experiences of a researcher setting out on her journey into the field of criminological research. In the burgeoning tradition of autoethnography, it will tell the story of how aspects of the researcher’s own ‘biography’ affected the data collection process in a study of ‘hidden’ older illegal drug users in the UK. The research employed snowball sampling and semi-structured interviews and at the outset great difficulties were encountered which were caused, in part, by the researcher’s age, nationality, professional standing and cultural awareness. However, as the researcher’s own personal biography developed over the long duration of the study, some of these problems were alleviated. In the process something of the nature of the participants themselves was revealed, namely their reticence to be too revealing to an ‘outsider’ about their illegal pastime, the manner in which their illegal drug use took place in a specific cultural milieu, and the extent to which they saw their drug use as being an unremarkable and normal part of their life. By the conclusion of the study, a by now older, more experienced and acculturated researcher was able to see this with far greater clarity. As criminology increasingly takes account of researcher biography, the argument presented here suggests that not only can it have significant impacts upon the research process, but even over the duration of a single study developments in the biography of the researcher can alter the nature of their relationship with research subjects and contribute to a greater understanding of them.
Worker Reallocation Over the Business Cycle: Evidence from Canada

This paper studies the cyclical variability of job finding, separations, and employer-toemployer flows in Canada for 1978-2016, the longest such time series available. Our analysis is based on direct administrative records of job separations. Our measures provide a much cleaner record of gross worker flows than standard household surveys. They are not subject to time-aggregation bias or to the measurement error problems that plague standard household surveys on employment dynamics. Employer-to-employer flows are strongly pro-cyclical and are the dominant component of both job finding and separation. We document several additional facts regarding the role of job-to-job flows in labor market fluidity, the near-constancy of the ratio of hires coming from employment versus unemployment, and the roles of “ins” vs “outs” in the Canadian labor market.
Language Difficulty and Prior Learning Influence Foreign Vocabulary Acquisition

When learning a foreign language, words that are the hardest to learn are often the easiest to forget. Yet, there is also evidence that more challenging learning contexts can lead to greater long-term retention. Here, we investigate the effect of language difficulty on vocabulary retention by teaching participants novel words that varied in both imageability and similarity to a known language over a period of four weeks. We found that easier words (high-imageability and familiar) were generally retained better than harder words (low-imageability and unfamiliar). However, when words were fully learned during training, the more difficult unfamiliar words were later recalled with higher accuracy than easier familiar words. The effect of language difficulty on vocabulary retention therefore varies depending on how well words were initially encoded. We conclude that greater challenges can reap greater long-term rewards so long as learners establish a strong foundation during initial acquisition.
EFL Learners’ Direct vs. Translated Writing in Different Writing Genres

With a new paradigm shifted from the interests in increasing each of language skills to those in developing integrated skills in ESL/EFL context, the importance and necessity of writing has been newly lighted on, now that writing has its own benefit to intensify other skills through complicated thinking process (Choi, 2009; Hardly, 1993; Hedge, 2005; (Chungnam National University) Kyeong-ok Yoon (Republic of Korea Air Force Academy)
CMAR_A_229631 10719..10729

*These authors contributed equally to this work Objective: Thyroid cancer has the highest prevalence among the cancer types that affect the endocrine system; however, its molecular mechanisms are not yet determined. Cadherin-16 (CDH16) plays an important role in the tumorigenesis of human cancers, but its influence on papillary thyroid cancer (PTC) is poorly investigated. This study aimed to explore the role of CDH16 in PTC. Methods: We performed quantitative real-time polymerase chain reaction to investigate CDH16 expression in PTC. The clinical significance of CDH16 expression in PTC was then evaluated using The Cancer Genome Atlas (TCGA) database. Bioinformatics analysis was also conducted to determine the potential molecular mechanisms of CDH16. Results: CDH16 was remarkably downregulated in PTC tumors compared with that in corresponding normal thyroid tissues in the local and TCGA cohorts. This downregulation was associated with unfavorable clinicopathological features, including histological type, high tumor stage, aggressive lymph node metastasis (LNM), and advanced clinical stage. In addition, logistic analyses revealed that the reduced expression of CDH16 can aggravate the risk of LNM in PTC. Bioinformatics analysis indicated that the co-expressed CDH16 genes mainly participated in signaling the cancer-related pathways. Conclusion: CDH16 is involved in PTC progression and acts as an LNM-related gene in PTC.
An Area Efficient Multiplier Design Using Fixed-Width Replica Redundancy

In this paper, proposedAn Area Efficient Multiplier Design Using Fixed-Width Replica Redundancy by adopting algorithmic noise tolerant (ANT) architecture with the fixed-width multiplier to build the reduced precision replica redundancy block (RPR). The proposed ANT architecture can meet the demand of high precision, low power consumption, and area efficiency. We design the fixed-width RPR with error compensation circuit via analysing of probability and statistics. Using the partial product terms of input correction vector and minor input correction vector to lower the truncation errors, the hardware complexity of error compensation circuit can be simplified. In a 16 × 16 bit ANT multiplier, circuit area in our fixed-width RPR can be lower and power consumption in our ANT design can be saved as compared with the state-of-art ANT design.
Interactive Effects of Propionic Acid and Temperature on Growth and Ochratoxin A Production by Penicillium aurantiogriseum

Propionate at concentrations up to 0.05 % decreased at 25 ~ the growth and sporulation of Penicillium aurantiogriseum. The standard size of conidiogenous structures (metulae, phialids) and conidia was diminished. The effect was more pronounced at a higher temperature (30 *C). Inhibition of ochratoxin production by propionate was also demonstrated. Ochratoxins constitute a group of closely related derivatives of isocoumarins linked to L-~-phenylalanine. Under natural conditions only ochratoxin A (OA) and, very rarely, ochratoxin B (OB) are produced and encountered as food contaminants (Krogh and Nesheim 1982).
Development of a new class of PSMA radioligands comprising ibuprofen as an albumin-binding entity

Prostate-specific membrane antigen (PSMA)-targeted radioligands have been used for the treatment of metastatic castration-resistant prostate cancer (mCRPC). Recently, albumin-binding PSMA radioligands with enhanced blood circulation were developed to increase the tumor accumulation of activity. The present study aimed at the design, synthesis and preclinical evaluation of a novel class of PSMA-targeting radioligands equipped with ibuprofen as a weak albumin-binding entity in order to improve the pharmacokinetic properties. Methods: Four novel glutamate-urea-based PSMA ligands were synthesized with ibuprofen, conjugated via variable amino acid-based linker entities. The albumin-binding properties of the 177Lu-labeled PSMA ligands were tested in vitro using mouse and human plasma. Affinity of the radioligands to PSMA and cellular uptake and internalization was investigated using PSMA-positive PC-3 PIP and PSMA-negative PC-3 flu tumor cells. The tissue distribution profile of the radioligands was assessed in biodistribution and imaging studies using PC-3 PIP/flu tumor-bearing nude mice. Results: The PSMA ligands were obtained in moderate yields at high purity (>99%). 177Lu-labeling of the ligands was achieved at up to 100 MBq/nmol with >96% radiochemical purity. In vitro assays confirmed high binding of all radioligands to mouse and human plasma proteins and specific uptake and internalization into PSMA-positive PC-3 PIP tumor cells. Biodistribution studies and SPECT/CT scans revealed high accumulation in PC-3 PIP tumors but negligible uptake in PC-3 flu tumor xenografts as well as rapid clearance of activity from background organs and tissues. 177Lu-Ibu-DAB-PSMA, in which ibuprofen was conjugated via a positively-charged diaminobutyric acid (DAB) entity, showed distinguished tumor uptake and the most favorable tumor-to-blood and tumor-to-kidney ratios. Conclusion: The high accumulation of activity in the tumor and fast clearance from background organs was a common favorable characteristic of PSMA radioligands modified with ibuprofen as albumin-binding entity. 177Lu-Ibu-DAB-PSMA emerged as the most promising candidate; hence, more detailed preclinical investigations with this radioligand are warranted in view of a clinical translation.
CMAR_A_221225 10767..10775

Department of Radiation Oncology, Tianjin Medical University Cancer Institute and Hospital, Key Laboratory of Cancer Prevention and Therapy, National Clinical Research Center for Cancer, Tianjin′s Clinical Research Center for Cancer, Tianjin 300060, People’s Republic of China Purpose: Thoracic radiotherapy (TRT) is the recommended therapeutic regimen for extensive-stage small cell lung cancer (ES-SCLC). Little is known about TRT benefits in elderly populations. The aim of this study was to evaluate TRT effects on the prognosis of elderly patients with ES-SCLC. Patients and methods: This retrospective analysis reviewed the records of patients over 65 years of age with metastatic ES-SCLC treated between 2010 and 2016. Enrolled patients received standard chemotherapy regimens (etoposide plus cisplatin or carboplatin). A total of 93 eligible patients were subjected to propensity score matching, which led to 40 patients being assigned to the TRT group and 40 to the no thoracic radiotherapy (noTRT) group. The cohort of 80 patients (67 males) had the median age of 69 years (range, 65–85 years), with a median of 4 chemotherapy cycle (range, 1–8 cycles), and a median chest irradiation dose of 50 Gy (range, 30–60 Gy). We analyzed overall survival (OS), progression-free survival (PFS), and local recurrence-free survival (LRFS) as endpoints; survival rates were determined by the Kaplan–Meier method and compared across groups with log-rank tests. Multivariate prognostic analysis was performed with Cox regression modeling, and categorical variables were analyzed with Chi-square tests. Results: In all patients, the 1-year OS, PFS, and LRFS rates were 38.3%, 16%, and 17.9%, respectively. The TRT group had superior survival outcomes compared to the noTRT group: their 1-year OS, PFS, and LRFS rates were 55% vs. 25% (P < 0.001), 32.1% vs. 0% (P < 0.001), and 31% vs. 2.6% (P < 0.001), respectively. TRT did not increase the incidence of adverse reactions (P = 0.431). Conclusion: TRT can improve chest tumor control and survival time in elderly ES-SCLC patients. Large-scale studies to further assess the benefits of TRT are warranted.
THEORY-PRACTICE TRANSITIONS AND DIS/POSITIONS IN SECONDARY MATHEMATICS TEACHER EDUCATION

One challenge for mathematics teachers and teacher education programs lies in translating socio-cultural theories into pedagogical practices. The study described in this paper endeavours to address the challenges faced by secondary mathematics pre-service teachers as they negotiate the transitions between/within university curriculum courses and their classroom field experiences as interns. This paper presents several theory-practice transitions, including those of the researcher, as it seeks to dis/position the power and tradition at the centre of secondary mathematics teacher education.
OTT_A_229033 10035..10041

Chenchen Cai* Haoliang Zhang* Yingxing Zhu* Peiming Zheng Yinhai Xu Jingfang Sun Miaomiao Zhang Ting Lan Bing Gu Shibao Li Ping Ma 1Department of Medical Technology, Xuzhou Medical University, Xuzhou 221004, People’s Republic of China; 2Department of Laboratory Medicine, Affiliated Hospital of Xuzhou Medical University, Xuzhou 221002, People’s Republic of China; 3Department of Laboratory Medicine, Henan Provincial People’s Hospital, Zhengzhou 450003, People’s Republic of China
Establishment a rat model for non-insulin-dependent diabetes mellitus induced by streptozotocin in combination with high-sugar and high-fat diets

Objective To investigate how to establish a rat model for non-insulin-dependent diabetes mellitus(DM) rat model induced by streptozotocin(STZ) in combination with high-sugar and high-fat diets.Methods 40 healthy male SD rats were randomly divided into the high-fat diet group,the DM control group and the normal group.STZ(60mg/kg) was injected intraperitoneally into rats in the high-fat diet group and the DM control group.Rats in the high-fat diet group were fed with high-sugar and high-fat diets for 4 weeks,but rats in the DM control group were fed with normal diet for 4 weeks.Rats in the normal group were injected intraperitoneally with the same dose of citric acid buffer,and were fed with normal diet for 4 weeks.The fasting blood glucose,body weight and urine sugar were detected 72 hours,1,4,8 and 12 weeks later.Results Fasting blood glucose,body weight of rats in high-fat diet group or DM control group increased significantly than those in normal group(P0.05). High blood glucose in high-fat diet group could maintain longer than that in DM control group,and urine sugar in high-fat diet group was more positive than that in DM control group.Conclusion The rat model of DM could be successfully induced by STZ in combination with 4-week high-sugar and high-fat diets.
Disposition Effect, Endowment Effect, Attachment Bias and Investment Advisers

In the context of stock market decision-making and investment processes, the impact of the disposition effect, the endowment effect and the attachment bias is great. The present research, based on answers given by 81 certified stock exchange executives, demonstrates the effect of the above biases on the subjects’ rational investment decisions and choices and the significant role of certified executives in the operation and processes of the stock market.
CFD modelling and experimental validation of particle-to-fluid mass and heat transfer in a packed bed at very low channel to particle diameter ratio

In this paper, the mass and heat transfer characteristics of a composite structured catalytic reactor packing (Composite Structured Packing (CSP)) are investigated. A CSP consists of a multichannel framework filled with ordinary catalyst particles, with a square channel-to-particle-diameter ratio ( N) of 1 < N < 5, resulting in a system with a significantly lower pressure drop compared to a randomly packed bed. The goal of the present study is to assess whether commercial Computational Fluid Dynamics (CFD) software can be used to (1) adequately predict the rate of mass and heat transfer from the catalyst particles to the fluid in a CSP and (2) develop simple engineering correlations for this type of packing. First, it is shown that commercial CFD software (CFX-5.3) can be used to adequately predict the particle-to-fluid heat transfer of a single free sphere. Furthermore, it is shown that the CFD code can predict the heat/mass transfer characteristics, with an average error of 15% compared to experimental values, for packed beds of spherical particles with 1.00 N 2.00. The constants of the commonly used engineering correlation Nu = c1 + c2RePr were obtained by fitting the CFD results forN = 1.00, 1.15, 1.47, 2.00 A and 2.00B. © 2003 Elsevier B.V. All rights reserved.
Proceedings of Meetings on Acoustics

Technology Educational Shops (TES) are designed to develop high school students' technological literacy. Their acoustical conditions play a dominant role in the quality of these environments. TES are, at the same time, classrooms for learning and industrial workshops for making things. Each use has its own standards governing its acoustical characteristics: ANSI S12.60-2002 for classrooms and the Ondet & Sueur DL2 criteria for workshops. A major conflict could exist by using the same room for two different purposes. This study investigated this conflict by evaluating the acoustical characteristics of 20 unoccupied wood, metal and automotive shops. It conducted measurements of background noise level (BNL), reverberation time (RT), speech intelligibility index (SII) and DL2. Results showed that BNLs and RTs in most TES were higher than the acceptability criteria for unoccupied core learning spaces. SII values indicated bad/poor speech intelligibility for normal and raised voice levels and reasonable/good speech intelligibility for loud and shout voice levels. DL2 values were found acceptable in about 80% of the TES. In general, these results indicate the poor acoustical conditions of TES as classrooms, and the need for special sound control measures.
DIPARTIMENTO DI ECONOMIA INTERNAZIONALE DELLE ISTITUZIONI E DELLO SVILUPPO

We claim that the emergence of trust is best explained by relation-based arguments. After briefly surveying alternative explanations which concentrate on material payoffs both with self-centered and with other-regarding preferences, we examine theoretical discussions of cooperative and trust behavior framed in terms of attitudes, esteem and, most of all, intentions. An important implication of all these approaches is that the relational element makes human interactions different, as it is also documented by a lot of evidence produced by neuroeconomic experiments. When trust is based on relations and on the recognition of the others’ intentions, efficient outcomes are brought about by the agents’ (at least) partial disregard for the maximization of their material payoff and by heavily personalized interactions. Both these features are distinctive of the functioning of communities and the particular way how they work and solve coordination problems.
The Cooling Efficiency of Urban Greenery Coverage in a High-density City

Urban greenery especially trees has been identified as one of the most effective measures for urban climate moderation through the mechanism of evaporative cooling and shading. For subtropical high-density cities like Hong Kong, intense heat stress arises from the compact urban form, poor ventilation, and the high percentage of impervious urban cover. Thus, concerted actions are being taken to harness the cooling potential of urban greenery for improved microclimate. However, the cooling effects of urban greenery vary based on multiple factors, including background climates, urban morphology, anthropogenic heat emission, vegetation types and quantity, etc. This study aims at quantifying and comparing the cooling efficiency of different urban greenery coverage for a typical residential neighbourhood in Hong Kong. The questions guiding our research are: what is the relationship between tree coverage and ambient environment, including air temperature and thermal comfort during a typical summer day in the selected neighbourhood? To achieve this objective, we employed a previously validated ENVImet model setting of a typical summer day to conducted parametric studies of cooling benefit of variable tree coverage ratio from 0 to 30% at the interval of 2% on a typical summer day. The results verified the greenery had a higher cooling potential during period of maximum temperature than the whole diurnal time, 1 °C and almost 0.8 °C respectively for air temperature. This study also showed that increasing greenery coverage indeed lowers diurnal temperatures, but this relationship is logarithmic instead of linear. The ratio of change in cooling effects to greenery increase and then decreased gradually. Between the coverage ratio of 8%-35%, the cooling potential would be underestimated in a linear relationship. Greenery measures may lead to ineffective results if greening principles have not been comprehensive understood, such as greenery abundance, composition and types. The present study allows urban planners and managers to understand more in greenery amount for urban micro-climate in high-density cities.
CIA_A_218849 1871..1878

Peng Wang 1 Qing Wang Fang Li Meng Bian Kun Yang 1Department of Geriatrics, Fuxing Hospital, The Eighth Clinical Medical College, Capital Medical University, Beijing, People’s Republic of China; 2Department of Pharmacy, Fuxing Hospital, The Eighth Clinical Medical College, Capital Medical University, Beijing, People’s Republic of China; 3Centre for Evidence-Based Medicine, Xuanwu Hospital Capital Medical University, Beijing, People’s Republic of China Objective: This study aimed to compare the prevalence of potentially inappropriate medications (PIMs) among hospitalized elderly patients using Beers and Chinese criteria and identify the correlation between PIMs and the risk of hospital readmission and death. Methods: This study was conducted on geriatric patients aged ≥65 years at Beijing Fuxing Hospital between June 2015 and December 2017. The Beers criteria of 2015 and the Chinese criteria of 2017 were used to detect PIMs. Follow-ups were conducted for 12–36 months (or until patients’ death, if it came sooner). Cox proportional-hazards models were used to explore the correlations between PIM use and the risk of hospital readmission and death. Results: Of 508 patients, 352 (69.3%) and 339 (66.7%) had at least one PIM identified using the Beers criteria and the Chinese criteria, respectively. Proton-pump inhibitors in the Beers criteria and clopidogrel in the Chinese criteria were the most leading PIMs. PIMs identified using the Beers criteria were a risk factor for the all-cause hospital readmission. After adjusting for age, gender, comorbidity, and so forth, PIM use was still an indicator of rehospitalization. PIM grouping defined using the Chinese criteria was not associated with hospital readmission. PIM grouping defined using either criteria was not associated with all-cause death. Conclusion: The study showed a high prevalence of PIM use in China. PIMs defined using the Beers criteria increased the risk of hospital readmission. Clinicians should pay more attention to PIMs, carry out routine PIM assessment, and reduce adverse health outcomes in elderly patients.