Miracle-dz/UniFAR-FTUs huggingface dataset:
Relation between Admission Troponin Level and TIMI Flow, Myocardial Tissue Perfusion and Clinical Outcomes after Primary Percutaneous Coronary Intervention

Background: Cardiac troponin is a structural protein within the cardiac myocytes and is a highly sensitive and specific marker to diagnose cardiac cells injury and damage. Objective: This study aimed to detect the effect of troponin level assessed on admission on the angiographic and clinical outcome post primary PCI. Patients and Methods: We conducted a cohort study to assess the prognostic relation between rise of first troponin on presentation and primary PCI success and post-primary PCI clinical outcome either during the hospital stay or during the follow up period after discharge. This study was conducted on forty-four patients presented to the Emergency Department with STEMI and underwent primary PCI. Results: The TIMI flow grade post PCI was (I) in 5 patients (11.4%), (II) in 7 patients (15.9%) and (III) in 32 patients (72.7%). For the 32 patients who had TIMI III flow, we went for further analysis of reperfusion by assessing the myocardial blush by evaluating the TMPG. It was found that 3 patients (9.4%) had TMPG (I), 4 patients (12.5%) had TMPG (II) and 25 patients (78.1%) had TMPG (III). No patients were recorded to have major flow limiting dissection that ended with complications or coronary perforation. The in-hospital outcome was assessed and the total number of patients who had complications during hospitalization was 12 patients (27.3%). Conclusions: This study findings support that a single measurement of hs-cTnT provides significant incremental information to risk stratification after STEMI.
Theoretical Analysis of Sensitivity Enhancement by Graphene Usage in Optical Fiber Surface Plasmon Resonance Sensors

Aiming to investigate the graphene usage in optical fiber surface plasmon resonance sensor probes, a theoretical analysis of sensitivity, reflectance, normalized transmitted power, full width at half maximum, and figure of merit (FOM) as a function of the sensing region length for different configurations has been developed. Here, some noble metals, such as gold (Au), silver (Ag), and copper (Cu) have been used as part of the sensing region. Considering aqueous solutions as analytes, the deposition of graphene layers over the metallic layer has improved the performance of the sensor probes. Three graphene-optimized probes have been proposed, one for each metal. When considering water as the surrounding medium, the configuration Cu–graphene-coated probe is the most sensitive, with a sensitivity of 6241 nm/RIU, representing more than two times the sensitivity for a Cu-based probe. On the other hand, the Ag–graphene-coated probe presents the maximum FOM of 75.523 RIU−1. The deposition of graphene layers over the Au-coated probes causes an increase in the sensitivity from 2581 nm/RIU to 4201 nm/RIU.
Berom cultural beliefs and attitudes towards mental health problems in Nigeria: a mixed-methods study

ABSTRACT Beliefs and attitudes are essential in mental health discourse. However, cultural beliefs and attitudes towards mental health problems (ATMHPs) among the Berom people of Nigeria are under-researched. The present studies made original contributions using the Cultural Identity Model (CIM) as predictors to investigate ATMHPs, and semi-structured interviews to further explain the potential impact of cultural beliefs on MHPs. In study-1, N = 140 participants responded to questionnaires on ATMHPs and were analysed using multivariate multiple regression in RStudio. Study-2 interviewed N = 13 participants (n = 7 laypeople; n = 6 practitioners). Interviews were recorded, transcribed and analysed thematically. Study-1 findings showed CIM as a non-significant predictor of ATMHPs. However, in study-2, four themes emerged: Cultural beliefs that MHPs are caused by spiritual forces; Berom indigenous preference for traditional healing; Christian religious healing in Berom communities; and Western-trained mental health practitioners' perception of lay service-users. The authors concluded that the Berom traditional and Christian religious healings are beneficial.
Energy‐Efficient Organic Ferroelectric Tunnel Junction Memristors for Neuromorphic Computing

Energy efficiency, parallel information processing, and unsupervised learning make the human brain a model computing system for unstructured data handling. Different types of oxide memristors can emulate synaptic functions in artificial neuromorphic circuits. However, their cycle‐to‐cycle variability or strict epitaxy requirements remain a challenge for applications in large‐scale neural networks. Here, solution‐processable ferroelectric tunnel junctions (FTJs) with P(VDF‐TrFE) copolymer barriers are reported showing analog memristive behavior with a broad range of accessible conductance states and low energy dissipation of 100 fJ for the onset of depression and 1 pJ for the onset of potentiation by resetting small tunneling currents on nanosecond timescales. Key synaptic functions like programmable synaptic weight, long‐ and short‐term potentiation and depression, paired‐pulse facilitation and depression, and Hebbian and anti‐Hebbian learning through spike shape and timing‐dependent plasticity are demonstrated. In combination with good switching endurance and reproducibility, these results offer a promising outlook on the use of organic FTJ memristors as building blocks in artificial neural networks.
INTEGRATED EFFECT OF MAGNETIZED WATER AND BIOFERTILIZERS FOR ENHANCING THE PRODUCTIVITY OF MAJORANA HORTENSIS L. PLANT

This investigation was carried out at the experimental farm of the faculty of Agriculture, Menoufia Univ. at Shiben El-Kom during to growing the seasons of 2017 and 2018 to study the effect of some magnetized water and biofertilization on the growth, herb yield and essential oil content of Majorana hortensis L. plants. The N2-fixing bacterial strains of Rizobium, Azospirillium and Azotobacter were used as biofertilizers in current study. The plants were irrigated either with normal or magnetized irrigation water. The magnetized water was obtained by passing the water through magnetron tube of 2 inches diameter and 4000 Gauss's strains. The obtained results showed that the growth and herb yield parameters were markedly improved as a result of watering with magnetic water besides using bio fertilizers (Rhizobium, Azotobacter and Azospirillium). The best results in this respect were obtained by using magnetic water and Azotobacter fertilizer application compared to the control during both experimental season. Furthermore, the highest essential oil content and the percentages of N, P and K were enhanced as well by the combined application of magnetized water and Azotobacter application.
Responding to sexual violence: Women’s mobilization in war

Gender scholars show that women in situations of civil war have an impressive record of agency in the social and political spheres. Civilian women’s political mobilization during conflict includes active involvement in civil society organizations, such as nongovernmental organizations or social movements, and public articulation of grievances – in political protest, for example. Existing explanations of women’s political mobilization during conflict emphasize the role of demographic imbalances opening up spaces for women. This article proposes a complementary driving factor: women mobilize politically in response to the collective threat that conflict-related sexual violence constitutes to women as a group. Coming to understand sexual violence as a violent manifestation of a patriarchal culture and gender inequalities, women mobilize in response to this violence and around a broader range of women’s issues with the goal of transforming sociopolitical conditions. A case study of Colombia drawing on qualitative interviews illustrates the causal mechanism of collective threat framing in women’s collective mobilization around conflict-related sexual violence. Cross-national statistical analyses lend support to the macro-level implications of the theoretical framework and reveal a positive association between high prevalence of conflict-related rape on the one hand and women’s protest activity and linkages to international women’s nongovernmental organizations on the other.
Multiple Social and Academic Achievement Goals: Students’ Goal Profiles and Their Linkages

Abstract Students’ engagement in class stems from academic and social motivations, which can be expressed through their academic and social achievement goals. Using a person-centered approach, we investigated the configurations of academic and social achievement goals and their relevance for aspects of students’ academic (achievement, self-concept, goal structures) and social life (bullying, belonging). We relied on data from 1,759 Austrian secondary students. Latent profile analyses based on the students’ academic mastery, performance-approach, and performance-avoidance goals as well as social development, social demonstration-approach, and social demonstration-avoidance goals were conducted. Relations to aspects of students’ social and academic life were investigated through structural equation modeling. We identified five profiles that were each differentially associated with these variables: (a) weak pursuit of all goals, (b) strong mastery and development but weak performance and demonstration goals, (c) strong mastery and development but moderate performance and demonstration goals, (d) strong mastery and strong performance goals paired with strong social development, demonstration-approach, and demonstration-avoidance goals. Findings from additional variable-centered analyses indicated that while profile analyses are helpful to explain how academic and social goals are combined within individuals, researchers primarily interested in explaining differences in students’ academic and social functioning might derive clearer results through variable-centered approaches.
University of Birmingham Motivation-related predictors of physical activity engagement and vitality in rheumatoid arthritis patients

of inherent interest and enjoyment. People engaging for controlled reasons may feel they have been forced to exercise for extrinsic rewards and/or participate out of the feelings of guilt (e.g. to please their partner and/or because their general practitioner told them to be more active). Abstract This study tests the Basic Psychological Needs Theory (within the Self-determination framework), in relation to the prediction of physical activity and well-being among rheumatoid arthritis patients. Motivation regulations for physical activity were also considered in the process model. A total of 207 patients (150 females, mean age = 58 ± 11 years) completed a questionnaire pack and structural equation modelling was used to test expected relationships. Autonomy support provided by important other(s) regarding physical activity positively predicted rheumatoid arthritis patients’ need satisfaction which positively related to autonomous reasons for physical activity participation. Autonomous motivation positively predicted reported physical activity participation levels and feelings of vitality.
SFRP1 Negatively Modulates Pyroptosis of Fibroblast‐Like Synoviocytes in Rheumatoid Arthritis: A Review

Secreted frizzled-related protein 1 (SFRP1) is a member of secretory glycoprotein SFRP family. As a primitive gene regulating cell growth, development and transformation, SFRP1 is widely expressed in human cells, including various cancer cells and fibroblast-like synoviocytes (FLS) of rheumatoid arthritis (RA). Deletion or silencing of SFRP1 involves epigenetic and other mechanisms, and participates in biological behaviors such as cell proliferation, migration and cell pyroptosis, which leads to disease progression and poor prognosis. In this review, we discuss the role of SFRP1 in the pathogenesis of RA-FLS and summarize different experimental platforms and recent research results. These are helpful for understanding the biological characteristics of SFRP1 in RA, especially the mechanism by which SFRP1 regulates RA-FLS pyroptosis through Wnt/β-catenin and Notch signaling pathways. In addition, the epigenetic regulation of SFRP1 in RA-FLS is emphasized, which may be considered as a promising biomarker and therapeutic target of RA.
Oligotrophic Phytoplankton Community Effectively Adjusts to Artificial Upwelling Regardless of Intensity, but Differently Among Upwelling Modes

Artificial upwelling has been proposed as a means of enhancing oceanic CO2 sequestration and/or raising fishery yields through an increase in primary production in unproductive parts of the ocean. However, evidence of its efficacy, applicability and side effects is scarce. Here we present part of the results of a 37-day mesocosm study conducted in oligotrophic waters off the coast of Gran Canaria. The goal was to assess in situ the effects of artificial upwelling on the pelagic community. Upwelling was simulated via two modes: i) a singular deep-water pulse and ii) a recurring supply every 4 days; each mode at four different intensities defined by the total amount of nitrate added: approx. 1.5, 3, 5.7, and 11 µmol L-1. In this study we focus on the phytoplankton response through size-fractionated 14C primary production rates (PP), Chlorophyll a and biomass. We observed increases in PP, accumulated PP, Chlorophyll a and biomass that scaled linearly with upwelling intensity. Upwelling primarily benefitted larger phytoplankton size fractions, causing a shift from pico- and nano- to nano- and microphytoplankton. Recurring deep-water addition produced more biomass under higher upwelling intensities than a single pulse addition. It also reached significantly higher accumulated PP per unit of added nutrients and showed a stronger reduction in percentage extracellular release with increasing upwelling intensity. These results demonstrate that oligotrophic phytoplankton communities can effectively adjust to artificial upwelling regardless of upwelling intensity, but differently depending on the upwelling mode. Recurring supply of upwelled waters generated higher efficiencies in primary production and biomass build-up than a single pulse of the same volume and nutrient load.
On the relation between duration and energy of non-repeating fast radio bursts: census with the CHIME data

A correlation between the intrinsic energy and the burst duration of non-repeating fast radio bursts (FRBs) has been reported. If it exists, the correlation can be used to estimate intrinsic energy from the duration, and thus can provide us with a new distance measure for cosmology. However, the correlation suffered from small number statistics (68 FRBs) and was not free from contamination by latent repeating populations, which might not have such a correlation. How to separate/exclude the repeating bursts from the mixture of all different types of FRBs is essential to see this property. Using a much larger sample from the new FRB catalogue (containing 536 FRBs) recently released by the CHIME/FRB Project, combined with a new classification method developed based on unsupervised machine learning, we carried out further scrutiny of the relation. We found that there is a weak correlation between the intrinsic energy and duration for non-repeating FRBs at z < 0.3 with Kendall’s τ correlation coefficient of 0.239 and significance 0.001 (statistically significant), whose slope looks similar to that of gamma-ray bursts. This correlation becomes weaker and insignificant at higher redshifts (z > 0.3), possibly due to the lack of the faint FRBs at high-z and/or the redshift evolution of the correlation. The ‘scattering time’ in the CHIME/FRB catalogue shows an intriguing trend: it varies along the line obtained from linear fit on the energy versus duration plane between these two parameters. A possible cosmological application of the relation must wait for faint FRBs at high-z.
Acromegaly and Colorectal Neoplasm: An Update

Acromegaly is a systemic disease caused by excessive inappropriate secretion of GH and IGF-I levels, resulting in many systemic complications, including cardiovascular, respiratory, metabolic diseases, and a possible increased risk of some neoplasias. Although many studies on acromegaly and cancer remain uncertain, most data indicate that colorectal cancer (CRC) incidence is increased in this population. The exact mechanism involved in the role of GH-IGF-I axis in CRC has not been fully explained, yet it is associated with local and circulating effects of GH and IGF-I on the colon, promoting angiogenesis, cell proliferation, risk of mutation, inhibition of tumor-suppressor genes and apoptosis, thus facilitating a tumor microenvironment. Nevertheless, population-based studies present controversial findings on CRC incidence and mortality. All worldwide guidelines and expert consensuses agree with the need for colonoscopic screening and surveillance in acromegaly, although there is no consensus regarding the best period to do this. This review aims to analyze the existing data on CRC and acromegaly, exploring its pathophysiology, epidemiological studies and their limitations, colonic polyp characteristics, overall cancer and CRC incidences and mortality, risk factors for colon cancer pathophysiology, and recommendation guideline aspects.
HUBUNGAN FUNGSI KOGNITIF DENGAN KUALITAS HIDUP PADA LANSIA

Background: The aging process could cause physical changes and lowered organ function. These changescan affect the quality of life of the elderly, such as impaired cognitive function. It was found that there are pros and cons of whether or not thecognitive function have relates with quality of life of the elderly. Objective: To know the relationship between cognitive function and quality of life. Methods: This research is a descriptive study of analytic with crosssectional design with the number of respondents as many as 124 elderly, aged ≥ 60 years in Panti sosial tresna werdha 4 Cengkareng, West Jakarta. By using MMSE questionnaire to assess cognitive function and WHOQOL-BREF for quality of life. Results:Respondents were most acquired aged 60-74 years (81.5%), female gender (59.7%), as well as the level of education under high School (79.8%). The results of the study of the relationship test between cognitive function and quality of life is p=0.003 in the physical aspect, p=0.000 in psychological, p=0.004 in social and p=0.002 in the environmental aspects of the quality of life. Conclusion: Cognitive function affects all aspects of quality of life in elderly.
CMAR_A_269528 2117..2123

*These authors contributed equally to this work Background: It has been reported that lncRNA SNHG10 (SNHG10) promotes the progression of liver cancer and osteosarcoma; however, the role of SNHG10 in acute myeloid leukemia (AML) remains unknown. This study was to explore the role of SNHG10 in AML. Methods: The expression of SNHG10 and miR-621 in BM mononuclear cells (BMMNCs) isolated from 60 AML patients and 60 healthy controls were determined by RT-qPCR. Correlation between SNHG10 and miR-621 was analyzed by Pearson correlation coefficient. The overexpression of SNHG10 and miR-621 in transfected AML cells was detected by RTqPCR, and the regulatory relationship between them was explored. Methylation-specific PCR (MSP) was applied to detect the methylation of miR-621 induced by the overexpression of SNHG10. CCK-8 assay was conducted to evaluate cell proliferation. Results: In this study, we found that the expression of SNHG10 was upregulated and the expression of miR-621 was downregulated in AML samples. Moreover, SNHG10 and miR-621 were inversely correlated across AML samples, and a high level of SNHG10 predicted poor survival of AML patients. Bioinformatics analysis showed that SNHG10 could be targeted by miR-621. In AML cells, miR-621 overexpression downregulated the expression of SNHG10, while SNHG10 overexpression could not affect the expression of miR-621. However, it was found that the reduction of miR-621 caused by SNHG10 overexpression might be due to the increase of miR-621 methylation. In addition, SNHG10 overexpression significantly promoted BMMNC proliferation, whereas miR-621 overexpression inhibited BMMNC proliferation and abolished the effect of SNHG10 overexpression on BMMNC proliferation. Conclusion: miR-621 targets SNHG10 to suppress cell proliferation in AML.
Autonomous Unwrapping of General Pallets: A Novel Robot for Logistics Exploiting Contact-Based Planning

In recent years, robotics has been largely applied to improve the efficiency of logistic processes. Pallets cover a crucial role in the logistic flow, since they represent the main way to store and ship items. When put onto pallets, the items are wrapped with plastic films to protect them and prevent them from falling. Despite being the first and necessary operation for handling the stacked goods, unwrapping—the task of removing the plastic films wrapped around the goods—has not yet been satisfactorily automated. We propose the first robotic solution for autonomous unwrapping of generally shaped pallets, including both homogeneous and heterogeneous pallets. Force and torque measurements are exploited to retrieve information on the collisions between the end-effector and the wrapped items or the plastic film. Based on the contact information, we design a novel reactive planning strategy that makes the unwrapping task effective and robust on pallets with uncertain position or shape. We present the results of an extensive experimental campaign to validate the proposed method. Note to Practitioners—This work is motivated by the fact that unwrapping machines are not yet common on the market. The few commercial examples are usually bulky machines that lack the flexibility to adapt to different and irregularly shaped pallets. Thus, the crucial operation of removing the plastic film around palletized goods is still mainly performed by hand. Blade handling, ladders, and electrostatic shocks are sources of potential injury. We propose a flexible, autonomous unwrapping robot suitable for both cuboid and irregularly shaped pallets. The robot is composed of a robotic arm, a custom cutting end-effector, a vision module, and a suitable planning and control unit. The reduced dimensions allow it to be mounted on a mobile base. The robot has been successfully tested on different pallet configurations. However, extensive testing in real-world scenarios should be carried out to assess both reliability and time efficiency in more realistic working conditions. Moreover, real pallets can reach considerable heights. Thus, a prismatic joint should be integrated to address such cases. Finally, unwrapping in the presence of typical plastic straps and different types of film, e.g., the shrink one, is to be evaluated.