Miracle-dz/UniFAR-FTUs huggingface dataset:
Impact of Musculoskeletal Pain on Health related Quality of Life (HRQoL) among Fishermen in Kano State (Nigeria)

Introduction: Fishing is among the most dangerous occupations worldwide. Fishermen do exhaust their locomotor system and therefore; it is highly possible for them to have musculoskeletal pain (MSP) which may subsequently affect their quality of life. The aim of this study was to assess the impact of MSP on health related quality of life (HRQoL) among fishermen in Kano State (KS) Materials and Methods: 124 subjects were recruited from the population of fishermen in KS in this cross sectional study using purposive sampling. Only participants that met the inclusion criteria were recruited, their Physical and anthropometric data were recorded. They completed self-administered questionnaire, NORDIC MSP assessment tool and EQ-5D questionnaire. Results: The mean age and BMI of the participants were 31.5±1.14 and 25.25±6.47 respectively. Highest percentage of MSP was reported in 2-5 joints (58.9%) within the last 12 months and 48.4% within the last 7 seven days, however, there was little prevention in activities of daily living for the last 12 months with 70.4% having no pain. The EQ-5D Questionnaire showed, there was more problem with pain dimension (78.23%) and least problem was reported in self-care dimension (17.74%), while the mean EQ-VAS score was 52.78±15.28. Finally, there was no significant relationship (P>0.05) between the last 12 months, 7days of present of MSP and last 12 months of MSP preventing usual activities and quality of life across all the domains of EQ-5D. Conclusion: Fishermen present with MSP in varying parts of their body, however their MSP doesn’t significantly affect their HRQoL.
Unconventional Approach with the Likelihood of Correlation Matrices

Numerical approximations are important research areas for dealing with complicated functional forms. Techniques for developing accurate and efficient calculation of combined likelihood functions in meta-analysis are studied. The first part of the thesis introduces a B-spline approximation for making a parsimonious model in the simplest case(2-dimensional case) of correlation structure. Inference about the correlation between vitamin C intake & vitamin C serum level is developed by using likelihood intervals and the MLE, along with comparison with conventional methods. The second part studies a multivariate numerical integration method for developing a better approximation of the likelihood for correlation matrices. Analyses for (1) intercorrelations among Math, Spatial and Verbal scores in an SAT exam and (2) intercorrelations among Cognitive Anxiety, Somatic Anxiety and Self Confidence from Competitive State Anxiety Inventory (CSAI-2) are explored. Algorithms to evaluate likelihood and to find the MLE is developed. Comparison with two conventional methods (joint asymptotic weighted average method & marginal asymptotic weighted average method) is shown.
6Li nucleosynthesis studied Big Bang 6Li nucleosynthesis studied deep underground (LUNA collaboration)

in addition to the well-known 7 Li problem. In the present work, the direct experimental cross section data on 2 H( α , γ ) 6 Li in the BBN energy range are reported. The measurement has been performed deep underground at the LUNA (Lab-oratory for Underground Nuclear Astrophysics) 400 kV accelerator in the Laboratori Nazionali del Gran Sasso, Italy. The cross section has been directly measured at the energies of interest for Big Bang Nucleosynthesis for the ﬁrst time, at E cm = 80, 93, 120, and 133 keV. Based on the new data, the 2 H( α , γ ) 6 Li thermonuclear reaction rate has been derived. Our rate is even lower than previously reported, thus in-creasing the discrepancy between predicted Big Bang 6 Li abundance and the amount of primordial 6 Li inferred from observations.
A Hybrid Network Intrusion Detection Technique Using Variable Multiplicative K-Means with Self-Organising PSO

: The intruders of the age have become more prominent in accessing vital information’s sans being attractive. Now a day the hackers go unnoticed stealing very sensitive information from the centralized network. The Network Intrusion Detection System (NIDS) is not adequate to tackle and identify these attack types. Over the period the types of attack have been upgraded to suit any improved Network Intrusion Detection Technique (NIDT). This improved attack scenario calls for a substantially improved approach in identifying the various newly mutated intrusions in the computing environment. In this paper we propose a bi-level solution. At first we propose a new modified version of K-Means technique called as Variable Multiplicative K-Means Algorithm (VMKMA). Next Self-Organising Particle Swarm Optimization (SOPSO) is used in the training phase to fine tune the parameters. The KDD Cup 99 dataset is used for the experimental purpose. The VMKMA proves to be dominant over other IDSs in terms of Detection Rate (DR), False Alarm Rate (FAR) and accuracy.
Surgical treatment of primary sarcoma of the lung

Objective : To study the results of surgical treatment of primary lung sarcoma. Methods : Between 1982 and 1998, we performed 18 macroscopically complete resections for primary sarcomas of the lung. The records of all patients were reviewed, as were pathological slides. Presence of symptoms, tumour size (more or less than 5 cm), complete resection, TNM stage and histology grade were analyzed for predictors of survival. Results : Patients comprised 11 women and seven men whose age ranged from 19 to 73 years (mean 50 years). Mean tumour diameter was 8.05 cm (range 2.5–15 cm) There were one grade 1, eight grade 2 and nine grade 3 tumours. Tumours in two patients were unresectable at ﬁrst presentation, and another was of doubtful resectability according to computed tomography scan. These three patients received pre-operative chemotherapy, with a partial response in the two unresectable patients allowing macroscopically complete resection in both cases. We performed 12 lobectomies (extended to the chest wall in two cases and to the diaphragm in two cases) and six pneumonectomies (extended to the chest wall in one case and the superior vena cava in one case). Operative and 30 days postoperative mortality were nil. Resection margins were invaded in two cases. Six patients received post-operative chemo- or radiotherapy and three others underwent repeat resections for pulmonary sarcoma recurrence. No patients were lost to follow-up. Pulmonary sarcomas recurred in eight patients (44%) leading to death in ﬁve cases after a mean period of 17 months. Overall median survival was 48 months, and actuarial 5-year survival 43%. Only TNM stage correlated with signiﬁcantly increased survival. Conclusion : As complete resection is the best therapeutic option for obtaining an acceptable survival rate in primary pulmonary sarcoma, pre-operative chemotherapy can be a useful adjunct in increasing the resectability of these tumours. q 2000 Elsevier Science B.V. All rights reserved.
Functional implications of the recognition of factor H-related protein 1 by anti-factor H autoantibodies in autoimmune hemolytic uremic syndrome

The autoimmune form of atypical hemolytic uremic syndrome (aHUS) is characterized by circulating autoantibodies against the complement regulator factor H, and is often associated with deficiency of the factor H-related proteins CFHR1 and CFHR3. We studied whether anti-factor H autoantibodies cross-react with CFHR1, and determined the functional consequence of this cross-reactivity. Autoantibodies from 24 aHUS patients were analyzed for factor H, CFHR1 and CFHR3 binding by ELISA. All 24 anti-factor H IgG bound to SCR20 of factor H, 21 also recognized CFHR1, but none bound to CFHR3. Three patients also had anti-factor H IgA cross-reacting with CFHR1. Analysis of the IgG fractions in CFHR1-deficient patients revealed that CFHR1-IgG complexes were formed during plasma treatment, demonstrating that autoantibodies recognize CFHR1 in vivo . The functional relevance of autoantibody binding to CFHR1 was analyzed in hemolysis assays using sheep erythrocytes. Recombinant CFHR1 prevented the lysis caused by patients’ plasma containing anti-factor H IgG, but it did not inhibit the lysis caused by a factor H mutation (W1183L) in SCR20. These results demonstrate that CFHR1 protects host cells from complement-mediated damage caused by the factor H-inhibitory autoantibodies. We conclude that exogenous CFHR1 provided during plasma exchange therapy contributes to the neutralization of anti-factor H autoantibodies, thus CFHR1 could be helpful in the treatment of autoimmune aHUS.
Impact of Ambient Temperature on Electricity Demand of Dhaka City of Bangladesh

Per capita electricity consumption of Bangladesh is 400 KWh. Of the total population of 160 million, only 40 percent has the access of using electricity. Dhaka city consumes about 40 - 45 percent of the total electricity generation of the country. This study reports the trend of electricity use in the Dhaka city with emphasis on the impact of changing temperature due to urbanization and weather change. Hourly data of electricity demand of Dhaka city and the temperature profile of the city for a period of thirty months have been used for this study. To relate weather data like temperature, humidity, wind speed, wind direction, atmospheric pressure, dew point and visibility etc. with electricity demand of the city about 16,508 data between 2011 and 2017 have been considered. A statistical regression has been done to establish a relation between them. From this study it is found that reduction of only 1&degC air temperature could save 81 MV of electricity consumption in Dhaka city. A time series forecast has been done to estimate probable temperature change and subsequent electricity consumption up to year 2020. From the study it has been established that the temperature dependence of electricity consumption in Dhaka city is about 75%.
CONTROLE DE INFECÇÃO RELACIONADA A CATETER VENOSO CENTRAL IMPREGNADO COM ANTISSÉPTICOS: REVISÃO INTEGRATIVA CONTROL DE INFECCIÓN RELACIONADA CON CATÉTER VENOSO CENTRAL IMPREGNADO CON ANTISÉPTICOS: REVISIÓN INTEGRADORA

Infection control related to central venous catheter impregnated with antiseptics: an integrative review Ferreira MVF, Andrade D, Ferreira AM Rev Esc Enferm USP 2011; 45(4):993-7 www.ee. usp.br/reeusp/ Infection control related to central venous catheter impregnated with antiseptics: an integrative review* C r it iC a l r e v ie w CONTROLE DE INFECÇÃO RELACIONADA A CATETER VENOSO CENTRAL IMPREGNADO COM ANTISSÉPTICOS: REVISÃO INTEGRATIVA
Who Would Bene t From Nasointestinal Tube in Small Bowel Obstruction?— A Matched Case-Control Study

Hui Wang Fujian Medical University Union Hospital Jun-rong Zhang Fujian Medical University Union Hospital Shuai Chen Fujian Medical University Union Hospital Ping Hou Fujian Medical University Qing-feng Chen Fujian Medical University Union Hospital Zong-qi Weng Fujian Medical University Union Hospital Xin-chang Shang-guan Fujian Medical University Union Hospital Bing-qiang Lin Fujian Medical University Union Hospital Xian-qiang Chen (  cxq760818@163.com ) Fujian Medical University Union Hospital
Eindeutigkeit der Zerlegung in Primzahlfaktoren in quadratischen Zahlkörpern*).

In einer Straßburger Dissertation hat Herr Jakob Schatunowski**) gezeigt, daß der Euklidische Algorithmus des größten gemeinschaftlichen Teilers in quadratischen Zahlkörpern mit einer Diskriminante der Form D=l — 4m, wo m > 3 ist, im allgemeinen nicht mehr zum Ziele führt; er hat dort einen anderen Algorithmus angegeben, welcher in allen den quadratischen Zahlkörpern anwendbar ist, in denen jede Zahl nur auf eine Weise in Primzahlfaktorqji***) zerlegt werden kann (ich nenne im folgenden solche Zahlkörper einfache Körper). Durch diese Arbeit angeregt, versuchte ich auch einen solchen Algorithmus zu finden, indem ich Euklids Algorithmus verallgemeinerte. Ein Schritt des Euklidischen Algorithmus besteht bekanntlich darin, daß das Zahlenpaar a, 6 durch das Zahlenpaar 6, r ersetzt wird, wo r der Rest der Division von durch 6 ist, d. h. eine Zahl der Form a — by, welche absolut kleiner als 6 ist. Dabei haben beide Paare dieselben gemeinsamen Teiler. In manchen quadratischen Körpern ist es aber nicht immer möglich, wenn a und gegeben sind, eine Zahl so zu finden,
Capturing the Family Context of Emotion Regulation: A Family Systems Model Comparison Approach

Several dimensions of family functioning are recognized as formative influences on children’s emotion regulation. Historically, they have been studied separately, limiting our ability to understand how they function within the family system. The present investigation tested models including family emotional climate, interparental conflict, and maternal and paternal warmth and emotional support in relation to children’s emotion regulation, using a multimethod, multi-informant design with 150 ethnically diverse two-parent families. Mother, father, and child surveys and observational techniques were used to assess the variables of interest. Three theoretically informed comprehensive models were tested and compared. The best fitting model highlighted positive family climate and maternal warmth and sensitivity as unique predictors. Interparental conflict was indirectly linked with children’s emotion regulation through both processes. This study underscores the value of evaluating family-wide, interparental, and parenting dimensions within a broader family systems model to gain a more complete understanding of children’s regulation.
Performance of a Modified Stator Current Based Model Reference Adaptive System Observer in Sensorless Induction Motor Drives

Abstract This article presents a modified stator current-based model reference adaptive system (SC-MRAS) observer for sensorless speed control of induction motor (IM) drives. The proposed MRAS algorithm utilizes the actual value and the estimation error of the stator current in an adjustable model of IM. Sensitivity analysis for the IM resistance variations is also studied. To enhance the robustness of the proposed method, an adaptation mechanism employs a fuzzy logic controller (FLC) instead of a conventional PI controller. A detailed simulation study using MATLAB/Simulink is presented. Experimental validation using a DSP-DS1104-based laboratory prototype is provided. Analytical, simulation, and experimental studies proved that superior performance and accurate speed estimation of the proposed observer at very low speed under different operating conditions are achieved.
Edinburgh Research Explorer Conflict of Evidence

Conflict of Evidence: Resolving discrepancies when findings from Randomized Controlled Trials and Meta-analyses disagree Abstract: Abstract 1 Context: Clinicians and treatment guideline developers are faced with a dilemma when the 2 results of a new, large, well conducted, randomized controlled trial (RCT) are in direct conflict 3 with the results of a previous systematic review (SR) and meta-analysis (MA). 4 Objective: To explore and discuss the possible reasons for disagreement in the results from 5 SRs/MAs and RCTs and to provide guidance to clinicians and guideline developers for making 6 well informed treatment decisions and recommendations in the face of conflicting data. 7 Evidence Acquisition: The advantages and limitations of RCTs and SRs/MAs are reviewed. Two 8 practical examples which have a direct bearing on EAU guidelines treatment recommendations 9 are discussed in detail to illustrate the points to be considered when conflicts exist between the 10 results of large RCTs and SRs/MAs. 11 Evidence Synthesis: RCTs are the gold standard for providing evidence of the effectiveness of 12 interventions, however concerns over an internal and external validity may limit their 13 applicability on clinical practice. SRs/MAs synthesize all evidence related to a given research question but two urological examples show that the validity of results depends on the quality of the individual studies, the clinical and methodological heterogeneity of the studies, 16 and publication bias. 17 Conclusions: when results to which should
up treatment for CRLF2-R ALL

Moving from genes to patterns of expression and to morphology, the authors show that the DMT cluster is characterized by an atypical morphology, whereas cases belonging to the other 3 categories display a more typical morphology. Subsequent analysis of expression of 1402 “microenvironmental” genes by RNA sequencing added an additional layer to this novel molecular stratification, by dividing SMZL in immune suppressive and immune silent subsets. The first subset is characterized by expression of genes typical of T cells, type 2 macrophages, and coding for exhaustion markers. These findings are in line with the concept that infiltrating immune cells cannot react against the tumor. Conversely, the immune silent subset essentially lacks expression of microenvironment-related genes, with an overt dominance of pathways belonging to tumor B cells, underlining that these tumors are not invaded by T cells. Interestingly, these expression profiles are equally distributed among genetic profiles, raising the question of what controls microenvironment organization. Mouse models recapitulating the different genetic lesions will likely be instrumental in providing additional information on how tumor cells shape the microenvironment. In addition, a possible role of infectious agents, for SMZL typically hepatitis C virus, needs to be addressed to determine whether it can induce a T-cell-rich and exhausted, or a T-cell–depleted environment.
A Zero-Inflated Negative Binomial Regression Model to Evaluate Ship Sinking Accident Mortalities

Sinking accidents are a seafarer’s nightmare. Using 10 years’ of worldwide sinking accident data, this study aims to develop a mortality count model to evaluate the human life loss resulting from sinking accidents using zero-inflated negative binomial regression approaches. The model results show that the increase of the expected human life loss is the largest when a ship suffers a precedent accident of capsizing, followed by fire/explosion or collisions. Lower human life loss is associated with contact and machinery/hull damage accidents. Consistent with our expectation, cruise ships involved in sinking accidents usually suffer more human life loss than non-cruise ships and there is be a bigger mortality count for sinking accidents that occur far away from the coastal area/harbor/port. Fatalities can be less when the ship is moored or docked. The results of this study are beneficial for policy-makers in proposing efficient strategies to reduce sinking accident mortalities.
Isolation and characterization of thermophilic Campylobacter species from geese raised in Kars region (Turkey) using cultural, molecular and mass spectrometry methods

Background: Thermophilic Campylobacters are found in the digestive tract of wild and domestic poultry and can be transmitted to humans following their fecal discharges. Aims: This study aimed to isolate thermophilic Campylobacter by culture from cloacal swabs of geese, commonly breeding in Kars region, and to identify the isolates by PCR and mass spectrometry. Antibiotics susceptibility and resistance genes of the isolates were also analysed. Methods: The study included 400 cloacal swab samples of clinically healthy geese. The samples were cultured on mCCDA medium following the pre-enrichment in Preston broth. Identification of the isolates was performed by phenotypic methods, PCR, and MALDI-TOF MS. Antibiotic susceptibility and resistance genes of the isolates were analysed with the disc diffusion method and PCR, respectively. Results: Thermophilic Campylobacter spp. were isolated from 157 (39.3%) samples. 151 (96.2%) isolates were identified Campylobacter jejuni and 6 (3.8%) Campylobacter coli by the phenotypic tests and PCR. Among 125 isolates analysed by MALDI-TOF MS, 119 (95.2%) were identified C. jejuni and 6 (4.8%) C. coli. The isolates’ resistance to ampicillin, tetracycline, ciprofloxacin, gentamicin, and azithromycin were found 33.8%, 41.4%, 75.2%, 12.1%, and 7.6%, respectively. The distributions of blaOXA61, tetO, gyrA, and aphA-3 genes were 3.2%, 90.8%, 50.8%, and 52.7%, respectively. Conclusion: Since geese are raised in pastures in the Kars region, protecting and not polluting the existing natural environment and preventing their contact with wild birds will prevent the spread of these microorganisms.
Growth Media Affects Microalgae Susceptibility to Disruption by Low-Frequency Power Ultrasound

The effect of microalgae growth medium on power ultrasound treatment of microalgal biomass was investigated. Chlorella vulgaris was grown in Bold's basal medium (BBM), Bristol's medium, sueoka medium, and MiracleGro All Purpose Water Soluble Plant Food. These media showed statistically indistinguishable intrinsic growth rates, averaging 0.052/day. Power ultrasound treatment was applied at 9.5 W for 5 min. MiracleGro showed chemical oxygen demand (COD) solvation post-sonication of 66%, twice that of other growth media per cell ruptured; which was unexpected based on observed consistent biomass quality. Media differences do not appear to have an effect on ultrasound power transfer; thus, C. vulgaris grown in MiracleGro medium has a decreased strength in terms of resistance to rupture by ultrasound. These results suggest that while biomass productivity and composition are important for the efficiency of extraction, media effects on the susceptibility of cells to pretreatment should not be ignored in overall process design.
COVID-19 Infection Risk amongst 14,104 Vaccinated Care Home Residents: A national observational longitudinal cohort study in Wales, United Kingdom, December 2020 to March 2021

Background: Vaccinations for COVID-19 have been prioritised for older people living in care homes. However, vaccination trials included limited numbers of older people. Aim: We aimed to study infection rates of SARS-CoV-2 for older care home residents following vaccination and identify factors associated with increased risk of infection. Study Design and Setting: We conducted an observational data-linkage study including 14,104 vaccinated older care home residents in Wales (UK) using anonymised electronic health records and administrative data. Methods: We used Cox proportional hazards models to estimate hazard ratios (HRs) for the risk of testing positive for SARS-CoV-2 infection following vaccination, after landmark times of either 7 or 21-days post-vaccination. We adjusted hazard ratios for age, sex, frailty, prior SARS-CoV-2 infections and vaccination type. Results: We observed a small proportion of care home residents with positive PCR tests following vaccination 1.05% (N=148), with 90% of infections occurring within 28-days. For the 7-day landmark analysis we found a reduced risk of SARS-CoV-2 infection for vaccinated individuals who had a previous infection; HR (95% confidence interval) 0.54 (0.30,0.95), and an increased HR for those receiving the Pfizer-BioNTECH vaccine compared to the Oxford-AstraZeneca; 3.83 (2.45,5.98). For the 21-day landmark analysis we observed high HRs for individuals with low and intermediate frailty compared to those without; 4.59 (1.23,17.12) and 4.85 (1.68,14.04) respectively. Conclusions: Increased risk of infection after 21-days was associated with frailty. We found most infections occurred within 28-days of vaccination, suggesting extra precautions to reduce transmission risk should be taken in this time frame.