Miracle-dz/UniFAR-FTUs huggingface dataset:
Multi-objective optimization of dual-arc blades in a squirrel-cage fan using modified non-dominated sorting genetic algorithm

In this study, a dual-arc profile parameterized by four geometric variables was designed to replace the original single-arc profile of a squirrel-cage fan used in a range hood, in order to improve the efficiency of the entire machine and the fan pressure. A modified Non-dominated Sorting Genetic algorithm coupled with a three-dimensional Reynolds-averaged Navier–Stokes computation is applied to search the optimum blade shape. Moreover, a relatively coarse but proven reliable grid model is employed to accelerate the optimization process, and a dynamic crowding distance is applied to improve the broad diversity of the Pareto front. The optimization results show that the optimal dual-arc blades are formed by a leading arc with a relatively smaller curvature and a trailing arc with a larger curvature, and the shape of the leading arc dominates the aerodynamic performance of the dual-arc blade. The blade schemes at two end of the Pareto front have increased the fan pressure and efficiency at the optimization point by 5.3% and 1.5%, respectively, but also result in a decline in another performance indicator. The best compromised solution in the middle of the Pareto front has improved the pressure by 2.6% without reducing the efficiency in the numerical calculation. Compared with the single-arc blade with the same inlet and outlet angle, the dual-arc blade has a higher fan pressure, but at the same time, the efficiency is negatively affected. Finally, the new impeller with optimized dual-arc blades is manufactured and tested, and the experimental results show an increment exceeds 2% in pressure and an unexpected slightly improvement in fan efficiency.
Constructing the postnational citizen?: Civics and citizenship education in the Australian National Curriculum

ABSTRACT Recent critiques of citizenship education have identified the need for curricula that cover not only civil, political, social and cultural aspects of political belonging and responsibility, but that orient students to the realities of global engagement and responsibility. Rather than focussing on national values, histories and political procedures, the argument is that active citizenship, cosmopolitan values and identities, social justice, globally responsible behaviours, and critical self-awareness should be the goals of such education. This paper develops a typology of citizenship education, and then examines the ‘Civics and Citizenship’ module of the new Australian National Curriculum to understand what type of citizenship is being promoted through the curriculum and the teaching resources. The research finds that despite some opportunities to engage students’ thinking more globally, and a positive focus on the rights and contributions of Australia’s Indigenous peoples, the main thrust of the curriculum is the promotion and perpetuation of traditional nationalist and proceduralist citizenship, rather than global or cosmopolitan citizenship. Some recommendations for potential improvements are made.
Modulation of synaptic transmission by interacting proteins and transporters.

The properties of synaptic transmission may be modulated by transporters which regulate neurotransmitter and ion concentrations, and by proteins which interact with ion channels and transporters. I have investigated this for inhibitory and excitatory synapses in the retina and the cerebellum, using electrophysiological (patch-clamp) techniques. For inhibitory synaptic transmission, I have (1) discovered that GAB Ac receptors in retinal bipolar cells are modulated by the intracellular cytoskeletal protein MAP-IB, and shown that disrupting the interaction between MAP-IB and the GAB Ac receptor increases the sensitivity of the receptor to GAB A, which is expected to alter the duration of the inhibitory postsynaptic current in these cells; and (2) studied the possibility that chloride transporters maintain a non-uniform intracellular chloride distribution in retinal bipolar cells, which determines the direction and magnitude of the G ABA evoked membrane potential changes in the cell. For excitatory synaptic transmission I have (1) studied glutamatergic synaptic transmission in the cerebellum of transgenic mice lacking either of the glutamate transporters GLT-1 or GLAST, and demonstrated that GLAST knockout prolongs the synaptic current at the parallel fibre to Purkinje cell synapse, but that knocking out GLT-1 or GLAST does not alter the mossy fibre to granule cell synaptic current; (2) studied the effect of glycine on mossy fibre to granule cell synaptic transmission in the cerebellum of the rat, showing that the NMD A receptor glycine site is saturated even when no glycine is added to the superfusing solution; and (3) studied the properties of the LIM protein Ajuba, which interacts with the major glial glutamate transporter GLT-1, and shown that Ajuba does not modulate the transporter’s glutamate sensitivity, its associated anion channel, or the number of transporters in the plasma membrane.
Joint Impact of the Conditional Cash Transfer on Child Nutritional Status and Household Expenditure in Indonesia

This study investigates the impact of a conditional cash transfer program in Indonesia, the Program Keluarga Harapan (PKH), on the marginal and joint distributions of child nutritional status and household expenditure 26–30 months after its implementation. The PKH increases the higher quantiles of weight-for-age z-score among children aged between 25 and 36 months. Its improvement is explained not by the rise in household expenditure due to the PKH but by the change in the association between nutritional status and household expenditure. Furthermore, the PKH strengthens the positive association between nutritional status and household expenditure.
Oral administration of monosodium glutamate alters growth and blood parameters in female rabbits

Thirty-two female rabbits were used to evaluate the impact of varied doses of aqueous solution of monosodium glutamate (MSG) - a food additive, on growth performance and blood parameters in cross-bred rabbits. The rabbits were randomly assigned into four groups of eight rabbits each. Group 1 received no MSG, group 2 received 1 mg, group 3 received 2 mg, and group 4 received 4 mg per kg body weight of 40% aqueous solution of MSG every 48 hrs for nine weeks, constituting the control, low, medium and high dose groups, respectively. At the end of nine weeks of MSG administration, blood samples were obtained from 16 rabbits, consisting of four from each group for haematological and serum biochemical analyses. The mean feed intake and final weights gained by the rabbits significantly (p<0.05) increased with increased doses of MSG administered. The mean white blood cell values of those administered aqueous MSG were generally higher than those of the control, while significant reduction in the serum proteins of rabbits administered with MSG compared to the control was observed. The serum activities of AST and ALP as well as the cholesterol levels of rabbits administered 2 and 4 mg MSG/kg body weight were significantly higher (p<0.05) than those on control and low dose MSG. This study has shown that MSG, even at low doses, is capable of producing alterations in the body weight. The consumption of MSG should be reconsidered taking into account its hepatotoxic and dyslipidaemia effects.
EVALUATION OF OXIDATIVE STRESS IN SMOKING AND NON-SMOKING PATIENTS DIAGNOSED WITH ANXIOUS-DEPRESSIVE DISORDER

Oxidative stress is induced by tobacco smoking and is also associated with anxiety and depression, two common psychiatric disorders, frequently associated with tobacco use. The aim of this study was to correlate tobacco use and mixed anxiousdepressive disorder (MADD) with oxidative stress markers useful in clinical practice. A study assessing uric acid, vitamin c and malondialdehyde, as oxidative stress markers, was conducted in 31 smokers versus non-smokers with MADD. Other useful parameters assessed were: serum cholesterol, triglycerides and creatinine. Smoking profile was quantified by the number of packs-years (PY) and Fagerström nicotine dependence score (FNDS) with exhaled carbon monoxide (CO) validation, while MADD was certified by the Hamilton Anxiety/Depression Scale (HAM-A/D.) Malondialdehyde (MDA) serum concentration was significantly increased in 73% of the smokers, while vitamin C was lower in 90% of both smoking and no smoking MADD patients. Lower concentrations of uric acid were found in smokers, suggesting a decreased endogenous production. Smoking amplifies oxidative stress described in psychiatric disorders. Monitoring biomarkers of both tobacco exposure and oxidative stress can improve disease management.
Where does the tail begin? An approach based on scoring rules

Abstract Learning about the tail shape of time series is important in, e.g., economics, finance, and risk management. However, it is well known that estimates of the tail index can be very sensitive to the choice of the number k of tail observations used for estimation. We propose a procedure that determines where the tail begins by choosing k in a data-driven fashion using scoring rules. So far, scoring rules have mainly been used to compare density forecasts. We also demonstrate how our proposal can be used in multivariate applications in the system risk literature. The advantages of our choice of k are illustrated in simulations and an empirical application to Value-at-Risk forecasts for five U.S. blue-chip stocks.
Hubungan Tingkat Pendidikan dan Usia dengan Kejadian Diabetes Melitus di Wilayah Kerja Puskesmas Palaran Kota Samarinda Tahun 2019

Tujuan Penelitian : Tujuan dari penelitian ini adalah untuk menganalisis hubungan tingkat pendidikan dengan kejadian diabetes melitus dan hubungan usia dengan kejadian diabetes melitus di wilayah kerja Puskesmas Palaran Kota Samarinda. Metodologi : Penelitian ini merupakan penelitian kuantitatifdengan responden sebanyak 111, dengan 37 kasus dan 74 kontrol. Pengambilan sampel kasus menggunakan Total Sampling dan sampel kontrol menggunakan Propotional Random Sampling. Penelitian ini menggunakan desaincase control, analisis data dalam penelitian ini menggunakan metode analisis data chi square. Hasil : Hasil penelitian ini menunjukkan ada hubungan antara tingkat pendidikanP – Value = 0.002: OR 4.895, CI 95% 1,826 – 13,119. ), and age (P- Value = 0.000; OR 0.373, ci 95% 0.268- 0.519) dengan kejadian diabetes melitus. Manfaat : Hasil penelitian ini bisa dimanfaatkan menjadi sumber referensi dan sebagai bahan bacaan yang dapat menambah wawasan pembaca tentang tingkat pendidikan dan usia terhadap kejadian diabetes melitus.
Mechanical Performances and Structure Optimization of H-shaped Steel and Cement- Soil Wall

The H-shaped steel spacing and cement content are the key parameters of TRD (Trench cutting Re-mixing Deep wall), which directly affects the stress and displacement of the wall. To ensure the stability of the foundation pit, it is of great practical significance to optimize the steel spacing and cement content. Taking the urban utility tunnel in Hangzhou as the engineering background, the triaxial tests of cement-soil were conducted to study the influence of cement content on the strength of the cement-soil. The finite element model was established to analyze the deformation, stress distribution of cement-soil, and the spacing of H-shaped steel. Results show that the unconfined compressive strength and elastic modulus of cemented-soil increase linearly with the increase of the cement content in the range of 10%-25%. The tensile stress formed on the side of the foundation pit leads to the cement-soil damage, where there is the maximum horizontal displacement. According to the relationship between the cement content and the maximum H-shaped steel spacing, the optimized steel spacing and the cement content can be determined. The obtained conclusions can provide a reference for the similar engineering.
Sustaining warm and inclusive transitions across the early years: insights from the START project

ABSTRACT Positive transitions across home, ECEC and compulsory school education (CSE) are critical in promoting children’s development and educational achievement: this seems especially the case for children from migrant backgrounds. However, as a consequence of entrenched institutional practices and lack of ownership the issues by the different groups of professionals involved, the way transitions are managed tends to unintentionally favour children from more advantaged backgrounds, whose families know how to navigate the educational system, including its flaws. The article presents the findings from a transnational participatory action-research study (START) carried out in four countries (Italy, Slovenia, England, Belgium), discussing how an inclusive transition approach can better address the needs of migrant children and families in a holistic way.
Carbon, nitrogen and phosphorus stoichiometry in leaf, litter and soil at different vegetation restoration stages in the mid-subtropical region of China

Aims The aims of this study were to explore how vegetation restoration affects leaf, litter and soil C, N, P stoichiometry dynamics and nutrients cycling, and to characterize the homeostasis and nutrient use strategy of plants at different vegetation restoration stages in the mid-subtropical area of China. Methods Four vegetation types representing the successional sequence in the secondary forests were selected using the “space for time substitution” approach in central hilly area of Hunan Province, China, which consists of Loropetalum chinense + Vaccinium bracteatum + Rhododendron simsii scrub-grass-land (LVR), Loropetalum chinense + Cunninghamia lanceolata + Quercus fabri shrubbery (LCQ), Pinus massoniana + Lithocarpus reabsorption C:N. 3) During vegetation restoration, leaf N and P had significantly allometric growth relationship ( p < 0.01) with the allometric index being 1.45. The use efficiency of N and P nutrients in leaf showed decreasing trends and reabsorption efficiency showed increasing trends, and the lowest N use efficiency was observed in LCC and the lowest P use efficiency was in PLL, but the highest N, P reabsorption efficiency were both in PLL. 4) The leaf N content had weak homeostasis, and leaf P content had strong homeostasis to maintain P balance in plant under P limited in soil. Vegetation restoration had significant effects on leaf, litter and soil C, N, P contents and their stoichiometry. The C, N, P contents and their stoichiometry had significant correlations between leaf and soil. Plants could adapt to the shortage of soil nutrient supply mainly by reducing nutrient use efficiency and improving nutrient reabsorption capacity. The N and P cy-cles of the leaf-litter-soil system gradually reached the “stoichiometric equilibrium” during vegetation restoration.
Percepción social de la profesión de enfermería

La percepcion social que tenga una profesion esta directamente relacionado con lo que el profesional transmita de su propia identidad. En el caso especifico de la enfermeria, lleva en sus hombros una carga historica que, en lugar de darle prestigio, le dado estigmas, tales como: el uso de uniforme, el ejercicio enfermeria como castigo (pago de pecados) y el comienzo de la profesionalizacion con Florence Nightingale. Se realizo una revision bibliografica en bases de datos Scielo, Google Academico, Biblioteca virtual de salud de la OMS, con los terminos boleanos de “percepcion social” “enfermeria” “identidad profesional” y se obtuvieron 34 articulos cientificos de tipo revision o de reflexion; se seleccionaron articulos de menos de 5 anos que responda a la busqueda e interes del autor. Como resultados, se obtuvo que la enfermeria como profesion posee estigmas como debilidad, invisibilidad, poca autonomia, injusta remuneracion, juguete sexual y demas estereotipos. Se concluye que, si bien las creencias erroneas de enfermeria estan intricadas en la poblacion, el enfermero es el unico encargado de construir una identidad profesional solida, la cual se transmitira a la sociedad
Benefits and Risks of Antiretroviral Therapy for Perinatal HIV Prevention.

BACKGROUND Randomized-trial data on the risks and benefits of antiretroviral therapy (ART) as compared with zidovudine and single-dose nevirapine to prevent transmission of the human immunodeficiency virus (HIV) in HIV-infected pregnant women with high CD4 counts are lacking. METHODS We randomly assigned HIV-infected women at 14 or more weeks of gestation with CD4 counts of at least 350 cells per cubic millimeter to zidovudine and single-dose nevirapine plus a 1-to-2-week postpartum "tail" of tenofovir and emtricitabine (zidovudine alone); zidovudine, lamivudine, and lopinavir-ritonavir (zidovudine-based ART); or tenofovir, emtricitabine, and lopinavir-ritonavir (tenofovir-based ART). The primary outcomes were HIV transmission at 1 week of age in the infant and maternal and infant safety. RESULTS The median CD4 count was 530 cells per cubic millimeter among 3490 primarily black African HIV-infected women enrolled at a median of 26 weeks of gestation (interquartile range, 21 to 30). The rate of transmission was significantly lower with ART than with zidovudine alone (0.5% in the combined ART groups vs. 1.8%; difference, -1.3 percentage points; repeated confidence interval, -2.1 to -0.4). However, the rate of maternal grade 2 to 4 adverse events was significantly higher with zidovudine-based ART than with zidovudine alone (21.1% vs. 17.3%, P=0.008), and the rate of grade 2 to 4 abnormal blood chemical values was higher with tenofovir-based ART than with zidovudine alone (2.9% vs. 0.8%, P=0.03). Adverse events did not differ significantly between the ART groups (P>0.99). A birth weight of less than 2500 g was more frequent with zidovudine-based ART than with zidovudine alone (23.0% vs. 12.0%, P<0.001) and was more frequent with tenofovir-based ART than with zidovudine alone (16.9% vs. 8.9%, P=0.004); preterm delivery before 37 weeks was more frequent with zidovudine-based ART than with zidovudine alone (20.5% vs. 13.1%, P<0.001). Tenofovir-based ART was associated with higher rates than zidovudine-based ART of very preterm delivery before 34 weeks (6.0% vs. 2.6%, P=0.04) and early infant death (4.4% vs. 0.6%, P=0.001), but there were no significant differences between tenofovir-based ART and zidovudine alone (P=0.10 and P=0.43). The rate of HIV-free survival was highest among infants whose mothers received zidovudine-based ART. CONCLUSIONS Antenatal ART resulted in significantly lower rates of early HIV transmission than zidovudine alone but a higher risk of adverse maternal and neonatal outcomes. (Funded by the National Institutes of Health; PROMISE ClinicalTrials.gov numbers, NCT01061151 and NCT01253538 .).
Did Fund Managers Deliver Value During the Financial Crisis?

This study provides evidence that individual investors are better off by investing through mutual funds run by skilled fund managers, who not only deliver higher risk-adjusted returns in normal times but also attain similar performance even during turbulent economic states, such as the 2007–2009 global financial crisis. Specifically, we show that, on average, fund managers with the highest skill (top 20%) added $6.877 million of value annually during the early crisis period and $4.065 million of value during the late crisis period, compared with $3.198 million gain realized during the entire sample period. Low-skill fund managers (bottom 20%), however, lost $0.844 million of value during the early crisis period and $5.323 million of value during the late crisis period. TOPICS: Performance measurement, manager selection, wealth management Key Findings • Active managed mutual funds with skilled managers can serve an important insurance and value generating function not only during normal times but also in extreme economic downturns. • Funds run by skilled managers experienced significant capital inflows during both the early and late stages of the financial crisis, whereas their low skilled counterparts incurred significant capital outflows. • Fund management skill persists at least 1 year during the whole financial crisis period.
Functional Polymorphism of Coagulation Factor II Gene in Patients with Systematic Lupus Erythematosus and Its Correlation with Cardiovascular Events

Aim: To investigate the possible association of FII functional polymorphisms rs1799963 (G20210A) and cardiovascular events risk in Systemic Lupus Erythematosus (SLE). Methods: The present study was carried out on 40 patients with SLE selected from Al-Zahraa University Hospital in the period from April 2014 to April 2016. The FII functional polymorphisms rs1799963 (G20210A) was measured by Real Time-Polymerase chain Reaction (RT-PCR). Results: The present study included 40 patients with SLE and 20 normal controls. There was non-significant difference as regard G20210A mutation in patients with SLE and normal controls. Similarly, there was non-significant difference as regard G20210A mutation in patients with cardiac complications in compared to patients without cardiac complications. When we compared the patients with and without history of cardiovascular complications, there were highly significant increase in patients with cardia complications regarding cardiac symptoms (P<0.001), vascular, and Pulmonary symptoms (P=0.002 and 0.035, respectively). Conclusion: In conclusion, SLE patients with G20210A mutation are not at increased risk of cardiovascular events.Keywords Systematic Lupus, G20210A mutation, Cardiovascular events