Miracle-dz/UniFAR-FTUs huggingface dataset:
Perceiving and misperceiving speech: lexical and sublexical processing in the superior temporal lobes

Abstract Listeners can use prior knowledge to predict the content of noisy speech signals, enhancing perception. However, this process can also elicit misperceptions. For the first time, we employed a prime–probe paradigm and transcranial magnetic stimulation to investigate causal roles for the left and right posterior superior temporal gyri (pSTG) in the perception and misperception of degraded speech. Listeners were presented with spectrotemporally degraded probe sentences preceded by a clear prime. To produce misperceptions, we created partially mismatched pseudo-sentence probes via homophonic nonword transformations (e.g. The little girl was excited to lose her first tooth—Tha fittle girmn wam expited du roos har derst cooth). Compared to a control site (vertex), inhibitory stimulation of the left pSTG selectively disrupted priming of real but not pseudo-sentences. Conversely, inhibitory stimulation of the right pSTG enhanced priming of misperceptions with pseudo-sentences, but did not influence perception of real sentences. These results indicate qualitatively different causal roles for the left and right pSTG in perceiving degraded speech, supporting bilateral models that propose engagement of the right pSTG in sublexical processing.
Low-Rank Plus Sparse Decomposition and Localized Radon Transform for Ship-Wake Detection in Synthetic Aperture Radar Images

The problem in obtaining stable motion estimation of maritime targets is that sea clutter makes wake structure detection and reconnaissance difficult. This letter presents a complete procedure for the automatic estimation of maritime target motion parameters by evaluating the generated Kelvin waves detected in synthetic aperture radar (SAR) images. The algorithm consists in evaluating a dual-stage low-rank plus sparse decomposition (LRSD) assisted by Radon transform (RT) for clutter reduction, sparse object detection, precise wake inclination estimation, and Kelvin wave spectral analysis. The algorithm is based on the robust principal component analysis (RPCA) implemented by convex programming. The LRSD algorithm permits the extrapolation of sparse objects of interest consisting of the maritime targets and the Kelvin pattern from the unchanging low-rank background. This dual-stage RPCA and RT applied to SAR surveillance permits fast detection and enhanced motion parameter estimation of maritime targets.
REVIEW OF FACTORS DETERMINING LEGUMES SOD-SEEDING OUTCOME DURING PASTURE RENOVATION IN NORTH AMERICA

Synthese des facteurs determinant le succes de la renovation de pâturages par semis direct de legumineuses en Amerique du NordLa renovation de pâturages via l’introduction de legumineuses par semis direct, consistant en un semis sans labour dans une prairie dominee par des graminees, est une methode qui accroit la productivite et la qualite des pâturages. En Amerique du Nord, l’utilisation de cette methode croit en popularite. Cependant, les resultats sont variables et certains problemes persistent. Les facteurs determinant le succes de la renovation de pâturages par semis direct sont presentes. Une attention particuliere est portee au role et aux effets des herbicides. Ces derniers sont generalement utilises afin de reduire la competition exercee par la vegetation residente de graminees. L’utilisation de methodes physiques (ex. : fauche ou pâture) afin de reduire l’effet competitif des graminees est presentee comme alternative a l’utilisation d’herbicide.
Monopolar diathermy versus a vessel-sealing device for reducing postoperative drain output after simple mastectomy: randomized clinical trial

Abstract Background Electrosurgical devices are commonly used during mastectomy for simultaneous dissection and haemostasis, and can provide potential benefits regarding vessel and lymphatic ligation. The aim of this prospective RCT was to assess whether using a vessel-sealing device (LigaSure™) improves perioperative outcomes compared with monopolar diathermy when performing simple mastectomy. Methods Patients were recruited prospectively and randomized in a 1 : 1 manner to undergo simple mastectomy using either LigaSure™ or conventional monopolar diathermy at a single centre. The primary outcome was the number of days the drain remained in situ after surgery. Secondary outcomes of interest included operating time and complications. Results A total of 86 patients were recruited (42 were randomized to the monopolar diathermy group and 44 were randomized to the LigaSure™ group). There was no significant difference in the mean number of days the drain remained in situ between the monopolar diathermy group and the LigaSure™ group (7.75 days versus 8.23 days; P = 0.613) and there was no significant difference in the mean total drain output between the monopolar diathermy group and the LigaSure™ group (523.50 ml versus 572.80 ml; P = 0.694). In addition, there was no significant difference in the mean operating time between the groups, for simple mastectomy alone (88.25 min for the monopolar diathermy group versus 107.20 min for the LigaSure™ group; P = 0.078) and simple mastectomy with sentinel lymph node biopsy (107.20 min for the monopolar diathermy group versus 114.40 min for the LigaSure™ group; P = 0.440). Conclusion In this double-blinded single-centre RCT, there was no difference in the total drain output or the number of days the drain remained in situ between the monopolar diathermy group and the LigaSure™ group. Registration number EudraCT 2018-003191-13 BEAUMONT HOSPITAL REC 18/66.
Open bisimulation for aspects

We define and study bisimulation for proving contextual equivalence in an aspect extension of the untyped lambda-calculus. To our knowledge, this is the first study of coinductive reasoning principles aimed at proving equality of aspect programs. The language we study is very small, yet powerful enough to encode mutable references and a range of temporal pointcuts (including cflow and regular event patterns). Examples suggest that our bisimulation principle is useful. For an encoding of higher-order programs with state, our methods suffice to establish well-known and well-studied subtle examples involving higher-order functions with state.Even in the presence of first class dynamic advice and expressive pointcuts, our reasoning principles show that aspect-aware interfaces can aid in ensuring that clients of a component are unaffected by changes to an implementation. Our paper generalizes existing results given for open modules to also include a variety of history-sensitive pointcuts such as cflow and regular event patterns.Our formal techniques and results suggest that aspects are amenable to the formal techniques developed for stateful higher-order programs.
A discrete representation of material heterogeneity for the finite-difference modelling of seismic wave propagation in a poroelastic medium

Peter Moczo,1,2 David Gregor,1 Jozef Kristek 1,2 and Josep de la Puente3 1Faculty of Mathematics, Physics and Informatics, Comenius University Bratislava, Mlynska dolina F1, 84248 Bratislava, Slovak Republic. E-mail: moczo@fmph.uniba. sk 2Earth Science Institute, Slovak Academy of Sciences, Dubravska cesta 9, 84528 Bratislava, Slovak Republic 3Barcelona Supercomputing Center, Nexus II – Planta 3C, Jordi Girona 29, 08034 Barcelona, Spain
On the control of oocyte meiotic maturation and ovulation in Caenorhabditis elegans.

Prior to fertilization, oocytes undergo meiotic maturation (cell cycle progression) and ovulation (expulsion from the ovary). To begin the study of these processes in Caenorhabditis elegans, we have defined a time line of germline and somatic events by video microscopy. As the oocyte matures, its nuclear envelope breaks down and its cell cortex rearranges. Immediately thereafter, the oocyte is ovulated by increasing contraction of the myoepithelial gonadal sheath and relaxation of the distal spermatheca. By systematically altering the germ cell contents of the hermaphrodite using mutant strains, we have uncovered evidence of four cell-cell interactions that regulate maturation and ovulation. (1) Both spermatids and spermatozoa induce oocyte maturation. In animals with a feminized germline, maturation is inhibited and oocytes arrest in diakinesis. The introduction of sperm by mating restores maturation. (2) Sperm also directly promote sheath contraction. In animals with a feminized or tumorous germline, contractions are infrequent, whereas in animals with a masculinized germline or with sperm introduced by mating, contractions are frequent. (3 and 4) The maturing oocyte both induces spermathecal dilation and modulates sheath contractions at ovulation; dilation of the distal spermatheca and sharp increases in sheath contraction rates are only observed in the presence of a maturing oocyte.
Antibody-epitope conjugates deliver immunogenic T-cell epitopes more efficiently when close to cell surfaces

ABSTRACT Antibody-mediated delivery of immunogenic viral CD8+ T-cell epitopes to redirect virus-specific T cells toward cancer cells is a promising new therapeutic avenue to increase the immunogenicity of tumors. Multiple strategies for viral epitope delivery have been shown to be effective. So far, most of these have relied on a free C-terminus of the immunogenic epitope for extracellular delivery. Here, we demonstrate that antibody-epitope conjugates (AECs) with genetically fused epitopes to the N-terminus of the antibody can also sensitize tumors for attack by virus-specific CD8+ T cells. AECs carrying epitopes genetically fused at the N-terminus of the light chains of cetuximab and trastuzumab demonstrate an even more efficient delivery of the T-cell epitopes compared to AECs with the epitope fused to the C-terminus of the heavy chain. We demonstrate that this increased efficiency is not caused by the shift in location of the cleavage site from the N- to the C-terminus, but by its increased proximity to the cell surface. We hypothesize that this facilitates more efficient epitope delivery. These findings not only provide additional insights into the mechanism of action of AECs but also broaden the possibilities for genetically fused AECs as an avenue for the redirection of multiple virus-specific T cells toward tumors.
Multiple intra-urban land use simulations and driving factors analysis: a case study in Huicheng, China

Simulations of intra-urban land use changes have gradually attracted more attention as these approaches are extremely helpful in regard to decision making and policy formulation. While prior studies mostly focused on methods of developing intra-urban level simulations, very little research has been conducted explain the factors driving intra-urban land use change. Urban planners are highly concerned with how inner-city structures are formed and how they function. Here, to simulate multiple intra-urban land use changes and to identify the contribution of different driving factors, we developed a random forests (RF) algorithm-based cellular automata (CA) simulation model. In this study, the model applied diverse categories of spatial variables, including traffic location factors, environmental factors, public services, and population density, as the driving factors to enhance our understanding of the dynamics of internal urban land use. The CA model was tested using data from the Huicheng district of Huizhou city in the Guangdong province of China. The Model was validated using actual historical land use data from 2000 to 2010. By applying the validated model, multiple intra-urban land use maps were simulated for 2015. Simultaneously, spatial variable importance measures (VIMs) were calculated by using the out-of-bag (OOB) error estimation approach of the RF algorithm. Based on the calculation results, we assessed and analysed the significance of each intra-urban land use driver for this region. This study provides urban planners and relevant scholars with detailed and targeted information that can aid in the formulation of specific planning strategies for different intra-urban land uses and support the future evolution of this area.
Archaic exploitation of small mammals and birds in Northern Chile

The employment in modern archaeological excavations of such intensive collection techniques as sifting the site matrix through fine screens or separating the excavated material in flotation devices results in the recovery of faunal samples that include large fractions of rodent and bird bone. The presence of these taxa, often previously unrecognized as a part of the ancient cultural environment, forces zooarchaeologists to enlarge their interpretive procedures to accomodate the particular problems these species present. The samples reported here, from 15 sites in Northern Chile are illustrative cases. Most were excavated by Prof. Lautaro Nunez of the Universidad del Norte in Antofagasta, while a few were dug by Dr. Gordon Pollard of SUNY Plattsburgh.
Moving Camera Registration for Multiple Camera Setups in Dynamic Scenes

This paper describes a method to register a moving (principal) camera, given a set of fully calibrated static cameras (witnesses) viewing a dynamic scene, a common scenario in broadcasting and film production. Our ultimate aim is to equip the existing free-viewpoint video algorithms with the ability to exploit any available moving cameras in generic dynamic scenes, and to facilitate 3D content production by augmented reality and stereoscopic rendering.
RITAS: Services for Randomized Intrusion Tolerance

Randomized agreement protocols have been around for more than two decades. Often assumed to be inefficient due to their high expected communication and computation complexities, they have remained overlooked by the community-at-large as a valid solution for the deployment of fault-tolerant distributed systems. This paper aims to demonstrate that randomization can be a very competitive approach even in hostile environments where arbitrary faults can occur. A stack of randomized intrusion-tolerant protocols is described and its performance evaluated under several settings in both local-area-network (LAN) and wide-area-network environments. The stack provides a set of relevant services ranging from basic communication primitives up to atomic broadcast. The experimental evaluation shows that the protocols are efficient, especially in LAN environments where no performance reduction is observed under certain Byzantine faults.
Multispectral Imaging

The field of anatomic pathology has changed significantly over the last decades and, as a result of the technological developments in molecular pathology and genetics, has had increasing pressures put on it to become quantitative and to provide more information about protein expression on a cellular level in tissue sections. Multispectral imaging (MSI) has a long history as an advanced imaging modality and has been used for over a decade now in pathology to improve quantitative accuracy, enable the analysis of multicolor immunohistochemistry, and drastically reduce the impact of contrast-robbing tissue autofluorescence common in formalin-fixed, paraffin-embedded tissues. When combined with advanced software for the automated segmentation of different tissue morphologies (eg, tumor vs stroma) and cellular and subcellular segmentation, MSI can enable the per-cell quantitation of many markers simultaneously. This article covers the role that MSI has played in anatomic pathology in the analysis of formalin-fixed, paraffin-embedded tissue sections, discusses the technological aspects of why MSI has been adopted, and provides a review of the literature of the application of MSI in anatomic pathology.
Sparse Bayesian Unsupervised Learning

This paper is about variable selection, clustering and estimation in an unsupervised high-dimensional setting. Our approach is based on fitting constrained Gaussian mixture models, where we learn the number of clusters $K$ and the set of relevant variables $S$ using a generalized Bayesian posterior with a sparsity inducing prior. We prove a sparsity oracle inequality which shows that this procedure selects the optimal parameters $K$ and $S$. This procedure is implemented using a Metropolis-Hastings algorithm, based on a clustering-oriented greedy proposal, which makes the convergence to the posterior very fast.
Benefit of endovascular treatment for primary versus secondary medium vessel occlusion: A multi‐center experience

Abstract Aims This study aimed to compare the clinical outcomes and safety of endovascular treatment (EVT) in patients with primary versus secondary medium vessel occlusion (MeVO). Methods From the endovascular treatment for acute ischemic stroke in the China registry, we collected consecutive patients with MeVO who received EVT. The primary endpoint was a good outcome, defined as a modified Rankin Scale (mRS) 0 to 2 at 90 days. Results 154 patients were enrolled in the final analysis, including 74 primary MeVO and 80 secondary MeVO. A good outcome at 90 days was achieved in 42 (56.8%) patients with primary MeVO and 33 (41.3%) patients with secondary MeVO. There was a higher probability of good outcomes in patients with the primary vs secondary MeVO (adjusted odds ratio, 2.16; 95% confidence interval, 1.04 to 4.46; p = 0.04). There were no significant differences in secondary and safety outcomes between MeVO groups. In the multivariable analysis, baseline ASPECTS (p = 0.001), final modified thrombolysis in cerebral infarction score (p = 0.01), and any ICH (p = 0.03) were significantly associated with good outcomes in primary MeVO patients, while baseline National Institutes of Health Stroke Scale (p = 0.002), groin puncture to recanalization time (p = 0.02), and early neurological improvement (p < 0.001) were factors associated with good outcome in secondary MeVO patients. Conclusion In MeVO patients who received EVT, there was a higher likelihood of poor outcomes in patients with secondary versus primary MeVO.
Research of effect on water resources carrying capacity in Beijing-Tianjin-Hebei region by water transfer

: The water resources shortage and water environment worsen have been becoming primary restraining factors to development of economy and society in Beijing- Tianjin- Hebei region. The evaluation of water resources carrying capacity is the key to regional water reasonable utilization. In this paper, according to the view of development of economy and society is supported by water resources, the eleven factors which mainly effect water resources carrying capacity have been selected as assessment indexes. An evaluation approach of research the effect on water resources carrying capacity by water transfer based on water quantity, water quality, water area and water flow has been established. The results indicate that the water carrying capacity are belong overloaded in Beijing-Tianjin-Hebei region, especially in Tianjin and Beijing. The carrying press is mostly from water resources system, the water shortage is the major reason of water carrying capacity overloading in Beijing-Tianjin-Hebei region, and the per capita water resources is the key factor to regional water carrying capacity. The water transfer is certainly important to improve water carrying capacity in Beijing- Tianjin- Hebei region, especially for Beijing and Tianjin. In drought period, the results of improve water carrying capacity by water transfer is more evident, for example the water resources carrying capacity had been improved 13% in Tianjin through water transfer from Luan River and Yellow River to Tianjin in 2000, when is very dry year. The south water to north make water carrying capacity improve 5% in Beijing and Tianjin, respectively. It supply an foundation for water resources reasonable utilization in Beijing-Tianjin-Hebei to research of effect on water resources carrying capacity by water transfer, and it is also important to realize the harmony among water resources, economy and society in region.
Design Approach for Anti-collision Mechanism between Vehicle to Vehicle for Improving Safety Operation In Intelligent Transportation System

InVeTraS (Intelligent Vehicular Transportation System) is proposed as a Vehicle-to-Vehicle (V2V) anti-collision mechanism that determines estimates and absolves collision courses between two or more vehicles based on a correlative and cooperative wireless networking concept. The problem of collision avoidance is abstracted to the generic problem of location awareness and subsequent periodic information exchange (between vehicles). To enable location awareness, the mechanism uses one of two techniques: a Global Positioning System (GPS) receiver aided with dead-reckoning sensors or a RADAR based measurement system. Two nearby vehicles periodically exchange information about their own movement in terms of exact position and local clock time. Using these inputs, vehicles determine whether or not they are on a collision course with each another. A Communication Cluster (based on the concept of mobile ad-hoc peer-to-peer networking) is formed, that facilitates the development of a vehicular network characterized by self organization, fault-tolerance, scalability, cooperation and cost efficiency. These characteristics enable avoidance of collision between vehicles in an adaptive and dynamic set up. The paper proposed InVeTraS concept by emulating the streets of Manhattan.
fMRI of triggerable aurae in musicogenic epilepsy

The authors studied a patient with musicogenic epilepsy triggered by one specific musical piece using 3D PRESTO fMRI. During epileptic aurae initiated by the stimulus, signal increases were found in the left anterior temporal lobe, correlating with ictal EEG and SPECT showing a left anterior temporal focus, and the right gyrus rectus. Because fMRI indicated a cascade of recruitment of the ventral frontal lobes by epileptogenic music, left anterior temporal lobe activity could be secondary to a right gyrus rectus focus, possibly triggered by emotional processing of music.
[Study on relation between Sp110 gene polymorphism and tuberculosis genetic susceptibility of Chongqing Han People].

OBJECTIVE To investigate the association of Sp110 gene SNP with tuberculosis occurrence of Chongqing Han people. METHODS Design Use the case-control study design, and collect risk factors of tuberculosis by questionnaires. Use multiple methods to detect rs1135791C/T, rs722555A/G, 5'-UTR rs11679983A/G, rs28930679C/T, rs9061A/G, rs1063154G/T, rs1047254A/G, rs3948464C/T points SNP polymorphism. Use SAS software to perform significance test. And use MDR software to analyze the cross action of SNP points related to tuberculosis susceptibility. RESULTS (1) the frequencies of Sp110 gene rs1135791CT genotype, rs722555 GG genotype, rs11679983 GG genotype, rs3948464CC genotype in the case group are significantly higher than those in the control group. (2) Logistic regression analyzes rs1135791C/T, rs722555A/G, rs11679983A/G, rs3948464C/T, smoking history, family with TB, per capita living space and BMI were with relation to tuberculosis. (3) Sp110 gene rs722555A/G has the cross action with 3 points: rs1135791C/T, rs11679983A/G and rs3948464C/T, respectively. CONCLUSION rs1135791C/T, rs722555 A/G, rs11679983A/G, rs3948464C/T may be the risk factors for susceptibility to tuberculosis in Chongqing Han People.