Miracle-dz/UniFAR-FTUs huggingface dataset:
Emergence of a colistin-resistant KPC-2-producing ST258 clone in Hungary

Nine Klebsiella pneumoniae isolates showing non-susceptibility to carbapenems were collected from three centres in the north-eastern region of Hungary. The minimum inhibitory concentrations (MICs) of antibiotics were determined by Etest. The putative production of a carbapenemase was tested by the modified Hodge test. The presence of blaKPC genes was verified by polymerase chain reaction (PCR) and sequencing. Furthermore, molecular typing was performed by pulsed-field gel electrophoresis (PFGE) and multilocus sequence typing (MLST). All isolates showed extensively drug-resistant (XDR) phenotype, and of these, eight isolates were highly resistant to colistin. The isolates carried blaKPC-2, blaSHV-12, blaTEM-1 and blaSHV-11. PFGE analysis of the nine KPC-2-producing Hungarian ST258 K. pneumoniae isolates, two KPC-2-producing Norwegian ST258 isolates and 33 CTX-M-15-producing ST11 isolates revealed the existence of one genetic cluster at an 88% similarity level. The overall results of the PFGE clustering, MLST and the presence of SHV-11 in both ST11 and ST258 suggest that this is the first hyperepidemic clonal complex of multidrug-resistant K. pneumoniae, probably CC258/CC340, possibly undergoing worldwide spread. Á. Tóth (*) : L. Jánvári Department of Bacteriology, National Center for Epidemiology, Gyáli út 2-6, 1097 Budapest, Hungary e-mail: toth.akos@oek.antsz. hu L. Jánvári e-mail: janvari.laura@gmail.com I. Damjanova : J. Pászti Department of Phage Typing and Molecular Epidemiology, National Center for Epidemiology, Gyáli út 2-6, 1097 Budapest, Hungary I. Damjanova e-mail: damjanova.ivelina@oek.antsz. hu J. Pászti e-mail: paszti.judit@oek.antsz. hu E. Puskás Laboratory of Microbiology, Northern Regional Institution of Hungarian National Public Health and Medical Officer Service, Meggyesalja u. 12, 3530 Miskolc, Hungary e-mail: puskas.erzsebet@emr.antsz. hu M. Farkas :A. Dobák Laboratory of Microbiology, Corden International Ltd., Budapest, Hungary M. Farkas e-mail: mfarkas@corden.hu A. Dobák e-mail: adobak@corden.hu K. Böröcz Department of Hospital Epidemiology and Hygiene, National Center for Epidemiology, Gyáli út 2-6, 1097 Budapest, Hungary e-mail: borocz.karolina@oek.antsz. hu Eur J Clin Microbiol Infect Dis (2010) 29:765–769 DOI 10.1007/s10096-010-0921-3
PERFORMANCE BASED EARTHQUAKE ASSESSMENT OF AN INDUSTRIAL GAS FILTER STRUCTURE

Industrial facilities often store a large amount of hazardous material and, in case of seismic event, there is a high probability that accidental scenarios as fire, explosion, toxic or radioactive dispersion may occur. Moreover, the structural configuration of industrial facilities are often the fruit of plants and functionality requirements, that lead to strong irregularities and different load resisting systems within the same structure. This paper presents a performance-based earthquake assessment of an industrial gas filter structure, characterized by the presence of important masses placed at significant height and of different horizontal resisting systems, such as moment resisting frames, inverted V bracings and diagonal bracings. Within the framework of the PROINDUSTRY research project critical failure mechanisms of industrial structures and relevant limit states are analyzed and discussed. The structural response is computed via nonlinear finite elements analyses of the static pushover (PO) and dynamic response history type (RHA). The seismic input is defined through Probabilistic Seismic Hazard Analysis (PSHA) and a set of natural Ground Motions (GM) which are selected and scaled with different criteria with respect to the Uniform Hazard Spectrum (UHS) and the Conditional Mean Spectrum (CMS). An overview of significant aspects of the structural performance assessment is presented with respect to input definition and choice of Intensity Measures (IM), irregular structural behaviour and probabilistic treatment of key Engineering Demand Parameters (EDP) for this type of industrial structure. 4184 COMPDYN 2017 6 ECCOMAS Thematic Conference on Computational Methods in Structural Dynamics and Earthquake Engineering M. Papadrakakis, M. Fragiadakis (eds.) Rhodes Island, Greece, 15 ! 17 June 2017 Available online at www.eccomasproceedia. org Eccomas Proceedia COMPDYN (2017) 4184-4193 © 2017 The Authors. Published by Eccomas Proceedia. Peer-review under responsibility of the organizing committee of COMPDYN 2017. doi: 10.7712/120117.5715. 18439 R. Laguardia, A. Piscini, M. Faggella, F. Morelli, R. Gigliotti, F. Braga, W. Salvatore.
RMHP_A_277375 2553..2561

1Family and Community Medicine Department, College of Medicine, Jouf University, Aljouf 42421, Saudi Arabia; 2Public Health and Community Medicine Department, Faculty of Medicine, Assiut University, Assiut 71526, Egypt; 3Family Medicine Department, Faculty of Medicine, Suez Canal University, Ismailia 41522, Egypt; 4College of Medicine, Jouf University, Aljouf 42421, Saudi Arabia Purpose: Mammography screening (MS) is an underutilized screening tool; although it is provided free of charge to the Saudi community. The present study aimed at assessing knowledge and barriers of mammography screening among women attending primary health centers in Aljouf region, Saudi Arabia. Materials and Methods: A cross-sectional study was carried out among 423 women aged 41–75 years attending ten primary health centers in Aljouf region, Saudi Arabia. Structured interviewing questionnaires were used for data collection. SPSS program, version 24 was used for data analysis. Results: The least reported risk factors of BC in this study were early menarche (14.9%), first pregnancy after the age of 30 years (18%), and late menopause (18.7%). Concerning knowledge of MS, 50.8% of the women correctly identified that mammogram is the ideal method for detecting BC. The most encountered personal barriers towards MS were lack of information about mammogram (69.5%), fear of exposure to radiation (67.4%), fear of discovery of BC (62.9%), being busy all the time (62.2%), and fear of cancer treatment (61.9%). Regarding economic barriers, 40% of the participants reported that taking sick leave from work is difficult while 37.8% revealed that mammogram is costly. Concerning health system barriers, the most common barriers were fear of error in diagnosis (62.6%), long time to take medical appointment (57%), and preferring not to have a mammogram except after a doctor recommendation (52.7%). The present study showed that women’s education and residence significantly predicted their knowledge. Furthermore, women’s education and income significantly predicted their barriers towards MS. Conclusion: Many barriers toward mammography screening were encountered in the present study. Addressing these barriers and raising awareness about MS may be of great value to increase its uptake by Saudi women.
ALUNG August 21/2

Savov, Jordan, R. Silbajoris, and S. L. Young. Mechanical ventilation of rat lung: effect on surfactant forms. Am. J. Physiol. 277 (Lung Cell. Mol. Physiol. 21): L320–L326, 1999. — Mechanical ventilation of the lung could affect surfactant turnover by alteration of its secretion, recycling, and degradation. In vitro studies of surfactant subfractions recoverable from lavage fluid have led to predictions about surfactant physiology in vivo that include morphological transformations. We used electron microscopy to study in situ lipid forms in alveoli of rat lungs after two ventilation strategies [15 min at pressures (cmH2O) of 20/0 or 20/10]. In control animals, 4% of the lipid profile area in the surface lining layer was myelin figures (MF), 14% was tubular myelin, 37% was vesicular forms (VF), and the remainder (45%) was hypophase. Compared with controls, the length-normalized sum of the lipid forms and the hypophase was two times as great in the lungs of the 20/0 group. MF were threefold higher in the 20/0 group and fivefold higher in the 20/10 group. VF doubled after ventilation at 20/0, but VF were the same as control after ventilation at 20/10. The results showed that a ventilation pattern of 20/0 compared with that of 20/10 group was associated with a significantly larger VF, suggesting an increased net production of these surfactant forms during a large tidal volume breathing pattern. These morphological results are consistent with published results using physical methods of fractionating lung lavage.
PHYTOCHEMICAL SCREENING AND ANTI HYPERLIPIDEMIC ACTIVITY OF METHANOLIC EXTRACT OF ARGYREIA NERVOSA IN ALBINO RATS

Argyreia speciosa (Linn. f.) (Family: Convolvulaceae, Synonyms: Argyreia nervosa) is used in the traditional Ayurvedic systems of medicine as well as in local health folklore. It is commonly known as Vidhaara in Hindi and Hawaiian Baby Woodrose and Elephant creeper in English. It is the large climber and seen throughout India up to an altitude of 500 m. A. speciosa possess various pharmacological activity such as anti-aging, gastroprotective, analgesic & anti-inflammatory, aphrodisiac, antiviral, antidiabetic, anticonvulsion, antioxidant, antidiarrheal, antiulcer, central nervous system depressant, nematocides, nootropic, anticancer and many more. Apart from this numerous phytoconstituents have been isolated from A. speciosa.In present study evaluated phytochemical screening and anti-hyperlipidaemic activity. Phytochemical testing of the remove reveals the visibility of chemical components like Alkaloids, steroids, fixed oils, cardio tonic aglycones, flavonoids, saponins, carbohydrates, healthy proteins, resins. Severe OECD guide line no. 423, ED50 value was discovered to be 200mg/kg and also 400mg/kg.Anti Hyperlipidaemic activity was done by regimen caused technique. In today plasma HDL-cholesterol with a concomitant percent decrease from various other lipid was observed. It can be wrapped up from the here and now data that the levels of overall product cholesterol, triglyceride and also MDA which are really elevated in high fat diet regimen, can be lowered substantially with Argyreia nervosa and also antioxidant parameters SOD, GSH, Catalase which are actually can be increased significantly with Argyreia nervosa. Atherogenic index which in fact raised in atherogenic diet can be decreased considerably with Argyreia nervosa and also a very good % defense was seen with Argyreia nervosa and also basic medicineFrom this we can wrap up that the essence (Argyreia nervosa) Showed the anti-Hyperlipidaemic activity.
Segmentation and Depth Estimation of Urban Road

Deep learning for safe autonomous transport is rapidly emerging. Fast and robust vision perception for autonomous vehicles will be crucial for future navigation in urban areas with high traffic and human interplay. Previous work focuses on extracting full image depth maps, or finding specific road features such as lanes. However, in urban environments lanes are not always present, and sensors such as LiDAR with 3D point clouds provide a quite sparse depth perception of road with demanding algorithmic approaches. In this thesis we derive a novel convolutional neural network that we call AutoNet. It is designed as an encoderdecoder network for pixel-wise depth estimation of an urban drivable free-space road, using only a monocular camera, and handled as a supervised regression problem. AutoNet is also constructed as a classification network to solely classify and segment the drivable free-space in realtime with monocular vision, handled as a supervised classification problem, which shows to be a simpler and more robust solution than the regression approach. We also implement the state of the art neural network ENet for comparison, which is designed for fast real-time semantic segmentation and fast inference speed. The evaluation shows that AutoNet outperforms ENet for every performance metrics, but shows to be slower in terms of frame rate. However, optimization techniques are proposed for future work, on how to advance the frame rate of the network while still maintaining the robustness and performance. All the training and evaluation is done on the Cityscapes dataset. New ground truth labels for road depth perception are created for training with a novel approach of fusing pre-computed depth maps with semantic labels. Data collection with a Scania vehicle is conducted, mounted with a monocular camera to test the final derived models. The proposed AutoNet shows promising state of the art performance in regards to road depth estimation as well as road classification.
A STREPTOCOCCAL ENZYME THAT ACTS SPECIFICALLY UPON DIPHOSPHOPYRIDINE NUCLEOTIDE: CHARACTERIZATION OF T H E ENZYME AND ITS SEPARATION FROM ST1LEPTOLYSIN O* BY ARTHUR

Concentrated and partially purified preparations of streptococcal supernates containing streptolysin O have been shown to inhibit selectively the oxidative metabolism of mitochondria procured from the myocardium of rabbits and guinea pigs, the findings pointing to an interference with the action of the coenzyme diphosphopyridine nucleotide (DPN) (1). Further studies have demonstrated that these streptococcal preparations contain an enzyme, not hitherto discerned in streptococcal cultures, that specifically destroys DPN. Some of the characteristics of this enzyme, and its separation from streptolysin O, will be described in detail herein.
Archaeologia Polona :

Global climatic changes which occurred at the beginning of the Holocene had a huge impact on cultural development in northeast Africa. The shift of the tropical rain zone to the north led to the transformation of the desert into a savannah. The appearance of vegetation and animals also attracted people to considerable areas of the southern part of the Western Desert in Egypt. Settlement was concentrated around natural depressions or deflation troughs, which during periods of rain would fill with water creating seasonal lakes or playas. One such place is the playa located in Bargat El-Shab. Particularly intense traces of settlement dated to the climatic optimum of the Holocene was discovered on the eastern shore of the palaeolake (Site E-05-1). Artefacts are dispersed over an area of over 2 ha. Excavation conducted in a few locations also uncovered the remains of storage pits, hearths, wells, etc., the fills of which are characterised by an enhanced magnetization of features in the ground. The geophysical survey conducted during the last season of research provided exceptionally interesting data allowing the partial recreation of the actual extent of the site and its relation with the lake basin.
ISSN 2320-5407 International Journal of Advanced Research (2014), Volume 2, Issue 2, 206-212

Venu Govindappa Mitotic and meiotic chromosomes prepared from specimens of Ichthyophis italics tricolor collected from either side of Palghat Gap from three different locations of Western Ghats revealed a diploid number (2n=42-44) with Fundamental Number (62-64). Highest diplod number (44) and occurrence of chromosomal polymorphism is documented for the first time for gymnophion amphibians. Role of chromosomal rearrangements involved in karyotypic derivation process is discussed.
Fibrations with non commutative fibers

We study an analogue of fibrations of topological spaces with the homotopy lifting property in the setting of C∗-algebra bundles. We then derive an analogue of the Leray-Serre spectral sequence to compute the K-theory of the fibration in terms of the cohomology of the base and the K-theory of the fibres. We present many examples which show that fibrations with noncommutative fibres appear in abundance in nature.
ORAL LEUKOPLAKIA, HUMAN PAPILLOMAVIRUS AND CANCER TRANSFORMATION Factors related to human papillomavirus infection and cell proliferation

Oral leukoplakia (OL) is clinically diagnosed as a white oral lesion that cannot be scraped of or diagnosed as any other type of oral lesion. OL has the potential to transform into oral squamous cell carcinoma (OSCC). The gold standard treatment is a combination of surgical excision if possible, and surveillance. Despite complete removal, the risk of cancer or recurrence remains high. A major clinical problem is to predict which patients that have an OL that turns into OSCC. Infection with human papillomavirus (HPV), especially high risk (HR) HPV types has been attributed a role in cancer transformation of OL. HPV is a ubiquitous virus transmissible between humans and with a global variation in prevalence and known to cause cancer of the cervix uteri but also an important factor in oropharyngeal cancer. The overall aim of this thesis was to investigate the influence of HPV infection in OL, which clinical-, histopathological and treatment factors that affect the recurrence rate after surgical removal and to investigate molecular markers connected to cell proliferation and cancer transformation. The thesis is based on five scientific questions addressed in four different studies: Study I: Is there a correlation between overexpression of the tumour suppressor protein p16 and high-risk HPV infection in leukoplakia and OSCC? In this study the level expression of p16 in OL was assessed by immunohistochemistry and in the same group of patients OL tissue samples were analysed by Real-Time polymerase chain reaction (RT-PCR) for presence of twelve high-risk and two low-risk HPV types. In parallel, p16-expressing OSCC were analysed for the same HPV types. Study II: Has the prevalence of high-risk HPV in leukoplakia changed over time? Does the prevalence differ between Sweden, Romania and Brazil? In contemporary and historical patient cohorts from the three countries OL samples were analysed with RT-PCR for 12 high-risk and Oral leukoplakia, Human Papillomavirus and Cancer Transformation Factors related to human papillomavirus infection and cell proliferation
DEATH, CULTURE, HEAVY METAL AND INNER EXPERIENCE: SENSATION AND AFFECTIVITY

The present study aimed to investigate the possible relations between thanatological referentials present in heavy metal and the affective and sensory experience associated with death by participants of this artistic and cultural field. The research was based in a idiographic and qualitative introspectionist approach for the study of consciousness, whose proceedings culminated, in a first moment, in the identification and description of the emerging phenomenology of these experiences, in a second moment, in the discussion of the cognitive and affective processes underlying the emergence of the phenomenological content; and finally, in a third moment, in the discussion of the possible relations between the reported phenomenologies and the circumscription of death in heavy metal. Taken as a whole, the data indicated that both, the affective field and the sensory field reflects that the inner experience of death theme reflects major parameters of death representation in the West, which appear to overlap the narrower field of death representation in heavy metal.
Mesenteric Fibromatosis Simulating a Gastrointestinal Stromal Tumor: A Rare Cause of Intestinal Obstruction

Rasoaherinomenjanahary Fanjandrainy1, Rakotondrainibe Aurélia2, Razafindrainibe Tanjonirina3, Nomenjanahary Lalaina4, Tolotra Emmanuella Christina1, Solo Corinne5, Andriantsoa Mirana Jocya1 and Samison Luc Hervé1 1Digestive surgery Unit, University Hospital Joseph Ravoahangy Andrianavalona, Madagascar 2Surgical Intensive Care Unit, University Hospital Joseph Ravoahangy Andrianavalona, Madagascar 3Adult Intensive CareUnit, University Hospital of Gynecology Obstetrics of Befelatanana, Madagascar 4Anatomy Pathology Unit, University Hospital Joseph Ravoahangy Andrianavalona, Madagascar 5Surgery Unit, University Hospital Tanambao I –Antsiranana, Madagascar
AMEP_A_334155 1259..1265

1Department of Psychiatry, Nagoya City University Graduate School of Medical Sciences, Nagoya City, Aichi, Japan; 2Department of Anesthesiology and Intensive Care Medicine, Nagoya City University Graduate School of Medical Sciences, Nagoya City, Aichi, Japan; 3Department of Health Promotion and Human Behavior, Kyoto University Graduate School of Medicine/School of Public Health, Kyoto City, Japan Purpose: This study aimed to investigate the associations of the traits of autism spectrum disorder (ASD) and attention deficit hyperactivity disorder (ADHD) with depression and empathy among medical students. Patients and Methods: A cross-sectional survey was conducted with 202 fifth-year students at a Japanese medical school for 10 months during their clinical clerkship. The survey included sociodemographic questions and validated tools to measure depressive symptoms (Hospital Anxiety and Depression Scale [HADS]), medical students’ empathy for patients (Jefferson Scale of Empathy-Student version [JSE]), ADHD traits (ADHD SelfReport Scale Screener [ASRS Screener]), and ASD traits (Autism-Spectrum Quotient Japanese version-21 [AQ-J-21]). Results: A total of 151 students (response rate: 74.7%) participated in the survey. Of these, 41 (27.2%) reported a total score of ≥ 20 on the HADS and were categorized as depressed. Depressed students reported significantly lower and higher rates of having a part-time job and a history of enrolment in other faculties, respectively, than non-depressed students. According to the cutoff criteria of the ASRS Screener and AQ-J-21, 31 (20.5%) and 42 (27.8%) students reported ADHD and ASD traits, respectively. Multivariate regression analysis, controlling for age and sex, reported that higher age, ASRS Screener scores, and AQ-J-21 scores were significant predictors of higher HADS total scores. Additionally, higher AQ-J-21 scores significantly predicted lower JSE scores. Conclusion: The degree of ADHD and ASD traits was significantly associated with depression. Moreover, the degree of ASD traits was significantly associated with lower empathy for their patients. It is important to consider that about 20–30% of medical students have these neurodevelopmental traits and to develop intervention strategies for improving depression and empathy.
PARTIAL AND COMPLETE REPLACEMENT OF FISH MEAL WITH A MIXTURE OF DIFFERENT PLANT PROTEIN SOURCES IN JUVENILE MONO SEX NILE TILAPIA (Oreochromis niloticus) DIETS

A plant protein mixture (PPM) was tested to replace fish meal (FM) in diets for juvenile mono sex Nile tilapia, Oreochromis niloticus. Fish averaging (± SD) 3.27 ± 0.1 g were divided into 15 groups. Three groups were fed each of five isonitrogenous (30.4%) and isocaloric (4.7 kcal g -) diets replacing 0, 25, 50, 75, and 100% of fish meal protein with similar percentages of PPM (PPM 0, PPM25, PPM50, PPM75, or PPMI00, respectively). The PPM consisted of 25% peanut meal, 25% okara meal, 25% canola meal and 25% corn glutein meal. After 10 weeks of feeding, fish fed diets PPM50 exhibited growth performance and feed utilization not significantly different from fish fed control diet which contained 100% fish meal protein. Incorporation of plant protein mixture in mono sex Nile tilapia diets significantly decreased moisture, protein and fat content of whole body. The highest value of lipid content was recorded with fish fed 100% plant protein mixture meal (Diet 5) and the lowest was recorded with fish fed 100% FM protein (control, Diet 1). Based on the results of this study PPM diets were economically superior to FM diet. Therefore, these findings suggest that up to 50% of fish meal protein can be replaced by plant protein mixture in mono sex Nile tilapia diets without any adverse effects on growth performances, feed utilization and body composition.