Miracle-dz/UniFAR-FTUs huggingface dataset:
On-Demand Hydrogen Generation by the Hydrolysis of Ball-Milled Aluminum–Bismuth–Zinc Composites

In this investigation, ternary Al-Bi-Zn composites were prepared through mechanochemical activation to determine the combined effects of low-cost Bi and Zn on the morphology change and reactivity of the Al composite during the hydrolysis reaction. Specifically, Zn was considered as a means to slow the hydrogen generation rate while preserving a high hydrogen yield. A steady hydrogen generation rate is preferred when coupled with a proton exchange membrane fuel cell (PEMFC). Scanning electron microscopy (SEM) analysis indicated that Bi and Zn were distributed relatively uniformly in Al particles. By doing so, galvanic coupling between anodic Al and the cathodic Bi/Zn sustains the hydrolysis reaction until the entire Al particle is consumed. X-ray diffraction analysis (XRD) showed no intermetallic phases between Al, Bi, and/or Zn formed. A composite containing 7.5 wt% Bi and 2.5 wt% Zn had a hydrogen yield of 99.5%, which was completed after approximately 2300 s. It was further found that the water quality used during hydrolysis could further slow the hydrogen generation rate.
Accuracy and Survivability of Distributed Fiber Optic Temperature Sensors

Obtaining a high accuracy, high spatial resolution temperature profile of critical test artifacts and test components has long been the holy grail of temperature sensing. Optical Frequency-Domain Reflectometry (OFDR) facilitates the use of unaltered optical fiber as high resolution distributed temperature sensors. Coating selection is a major parameter to consider in determining the best sensor choice based on the operating environment, especially the temperature range. We assess the performance of several fiber sensor coatings for the purpose of converging to the best sensor option for the -40°C to 200°C range. Stripped and carbon coated fiber maintain uniformity through the temperature cycles, resulting in accuracies of +/-0.5°C. A packaged fiber sensor was also held at 551°C for 3000 hrs to measure its performance over time. The survivability and accuracy of fiber sensors at high temperatures provide clear advantages compared to single point thermocouples in terms of displaying localized temperature variations.
Heat stress changes mineral nutrient concentrations in Chenopodium quinoa seed

Abstract Quinoa is a popular seed crop, often consumed for its high nutritional quality. We studied how heat stress in the roots or the shoots of quinoa plants affected the concentrations of 20 elements (aluminum, arsenic, boron, calcium, cadmium, cobalt, copper, iron, potassium, magnesium, manganese, molybdenum, sodium, nickel, phosphorous, rubidium, sulfur, selenium, strontium, and zinc) in quinoa seed. Elemental concentrations in quinoa seed were significantly changed after an 11‐day heat treatment during anthesis. The type of panicle (main, secondary, and tertiary) sampled and the type of heat treatment (root only, shoot only, or whole plants) significantly affected elemental profiles in quinoa seed. Plants were also divided into five sections from top to bottom to assess the effect of panicle position on seed elemental profiles. Plant section had an effect on the concentrations of arsenic, iron, and sodium under control conditions and on copper with heat treatment. Overall, the time of panicle development in relation to the time of heat exposure had the largest effect on seed elemental concentrations. Interestingly, the quinoa plants were exposed to heat only during anthesis of the main panicle, but the elemental concentrations of seeds produced after heat treatment ended were still significantly changed, indicating that heat stress has long‐lasting effects on quinoa plants. These findings demonstrate how the nutritional quality of quinoa seeds can be changed significantly even by relatively short heat spells.
Comparing ethnobotanical knowledge of medicinal plants between community health workers and local experts in the “Mata da Paraíba” zone, northeastern Brazil

Abstract. Paiva Maia AC, da Costa Ferreira E, Marques de Lucena C, dos Santos Souza A, Dias da Cruz D, Paiva de Lucena RF. 2021. Comparing ethnobotanical knowledge of medicinal plants between community health workers and local experts in the “Mata da Paraíba” zone, northeastern Brazil. Biodiversitas 22: 5606-5616. The use of medicinal plants is an old practice in a society that has been transmitted to this day, with local experts recognized in many communities and being encouraged through public policies. In Brazil, Community Health Agents (CHWs) can be important for the dissemination of this practice, due to their work with the Health System and the community. This study aimed to compare the knowledge of medicinal plants between CHWs and local experts in the community of Timbó, the municipality of Jacaraú (Paraíba, northeastern Brazil). Semi-structured interviews were conducted addressing local names of plants, their indications, parts used, and preparation methods. The data on the species local importance were analyzed through the use value (UV) and relative importance (RI) methods. Local experts cited more species than CHWs. There was great local importance of some species both among local specialists and among CHWs. However, some species were highlighted exclusively among local specialists. Decoction and infusion stood out among the preparation methods and leaf, flower, and seed were the most prominent parts used. The diseases treated with plants are mainly related to the respiratory and digestive systems. Our findings show a correspondence between the CHWs’ knowledge and local experts’ knowledge, which leads us to believe that experts and CHWs may be sharing the same local knowledge in the study community.
SALSTM: An improved LSTM algorithm for predicting the competitiveness of export products

As international trade has been developing at an unprecedented rate, export product competitiveness is significant in a country's trade system. At present, neural network algorithms are extensively used in economic forecasting. Scholars have verified the effectiveness of neural networks, especially long short term memory (LSTM) model, compared with other nonlinear prediction methods. However, there are still research blanks in forecasting economic indicators related to export product competitiveness, and there is little research on the improved LSTM model combined with other algorithms. To address this limitation, this article established a quantitative index system for export product competitiveness composed of four highly recognized indicators such as revealed comparative advantage index, net export revealed comparative advantage index, international market share index, and economic value added. After collecting the relevant economic data, the single LSTM model was used to predict the future trend of China's machinery and equipment export product competitiveness. Based on the shortcomings exposed in applying single LSTM prediction, the article innovatively designs a combined forecast model of LSTM and seasonal autoregressive integrated moving average, and whose effectiveness and superiority are proved by the mean square error value. Finally, the article points out that this model plays an important role in national trade policy making. It is optimistic about the development of deep learning in international trade product competitiveness indicators prediction.
Monoterpene Synthase Genes and Monoterpene Profiles in Pinus nigra subsp. laricio

In the present study, we carried out a quantitative analysis of the monoterpenes composition in different tissues of the non-model conifer Pinus nigra J.F. Arnold subsp. laricio Palib. ex Maire (P. laricio, in short). All the P. laricio tissues examined showed the presence of the same fourteen monoterpenes, among which the most abundant were β-phellandrene, α-pinene, and β-pinene, whose distribution was markedly tissue-specific. In parallel, from the same plant tissues, we isolated seven full-length cDNA transcripts coding for as many monoterpene synthases, each of which was found to be attributable to one of the seven phylogenetic groups in which the d1-clade of the canonical classification of plants’ terpene synthases can be subdivided. The amino acid sequences deduced from the above cDNA transcripts allowed to predict their putative involvement in the biosynthesis of five of the monoterpenes identified. Transcripts profiling revealed a differential gene expression across the different tissues examined, and was found to be consistent with the corresponding metabolites profiles. The genomic organization of the seven isolated monoterpene synthase genes was also determined.
Evaluation of sequential organ failure assessment (SOFA) score efficiency
 in predicting the mortality of intensive care unit admitted COVID-19
 patients

Assessing the severity of the disease at the time of hospitalization can reduce the mortality of patients with coronavirus disease 2019 (COVID-19). For this stance, various scoring systems have been described to predict mortality rates. Sequential organ failure assessment (SOFA) is one of the scoring systems which have been used in this study. In order to calculate the SOFA score, demographic and characteristics information, clinical status, and laboratory findings were recorded from 154 patients with COVID-19, who have been admitted to the intensive care unit (ICU) for a period of 6 months. SOFA score was calculated in three time periods at the time of hospitalization, 72 hours after hospitalization, and the last day of hospitalization. Based on the outcome of the disease (death or recovery), patients were divided into two groups, and the results were analyzed in both groups. Statistical analysis has represented that the SOFA score was significantly higher in patients who died to compare with recovered ones in all time periods. Our findings suggest that SOFA scoring system can be used to predict mortality rate in ICU admitted COVID-19 patients.
Evaluation of Acute, Sub-Chronic Oral Toxicity Studies and Anti-Inflammatory Activity of Blumea mollis in Experimental Animals

Objective: The goal of this study was to test the ethanol extract of the aerial part of the Blumea mollis (Asteraceae) for acute and sub-chronic toxicity as well as anti-inflammatory efficacy. Methods: The shade dried aerial part of Blumea mollis (0.5 kg) was powdered and extracted with ethanol. Ethanol extracts was used for these studies. Acute oral and sub-chronic toxicity studies were performed as per OECD guidelines. The anti-inflammatory effect was studied by carrageenan-induced paw edema model in rats at dose levels 100, 200, and 400 mg/kg, orally. Results: The results indicate that ethanol extract of Blumea mollis was found to be safe at the dose of 2000mg/kg. The EBM 100, 200 and 400 mg/kg exhibited significant inhibition (p<0.001) of increase in paw edema in rats. Conclusion: The results of the experimental study confirmed that ethanol extract of Blumea mollis is devoid of toxicity and possesses significant anti-inflammatory activity.
True Grit: A Story of Perseverance Making Two out of Three the First Non-Animal Testing Strategy (Adopted as OECD Guideline No. 497)

In the last two decades, great strides have been made in developing alternative methods to animal testing for regulatory and safety testing. In 2021, a breakthrough in regulatory testing was achieved in that the first test strategies employing non-animal test methods for skin sensitization have been accepted as OECD guideline 497, which falls under the mutual acceptance of data (MAD) by OECD member states. Achieving this goal was a story of hard work and perseverance of the many people involved. This review gives an overview of some of the many aspects and timelines this entailed—just from the perspective of one stakeholder. In the end, the true grit of all involved allowed us to achieve not only a way forward in using test strategies for skin sensitization, but also a new approach to address other complex toxicological effects without the use of animals in the future.
The Development of a Model to Predict Sports Participation among College Students in Central China

This study applies the theory of planned behavior (TPB) and self-determination theory (SDT) to predict the sports participation and exercise intentions of college students in Central China by considering the mediating roles of attitudes, subjective norms, and perceived behavioral control. Structural equation modeling (SEM) was used to analyze self-reported data from 294 college students (144 males and 150 females). The relationship between the research variables was tested by the mediation model and Bootstrap 5000 sampling using AMOS version 24. The results show that the direct effects of attitudes and perceived behavioral control on motor intention and motor participation are significant in the model. The satisfaction of the three psychological needs had a positive indirect effect on motor participation through attitudes; competence and autonomy had a positive indirect effect on motor participation mediated through subjective norms; however, only competence had a positive indirect effect on motor mediated through perceived behavioral control. In conclusion, this research demonstrates the importance of meeting these three basic psychological needs when designing intervention measures to promote college students’ sports participation.
Relationship Between Social Responsibility and Financial Performance: Evidence from Indonesia

This empirical theoretical study investigates the two-way relationship between corporate social responsibility and financial performance in Indonesian businesses. The theoretical underpinning for the conceptual model is based on agency, stewardship, resource reliance, and stakeholder theory. The social behavior index is made up of four components: participation in global reporting initiatives, inclusion of Green Index firms, good compliance, Corporate Governance Recommendations, and signatories to the Global Compact. The study's findings reveal a positive relationship in both directions: social benefits and positive feedback that social policies increase financial resources. Increased financial success, on the other hand, boosts the social and economic benefits of enacting rules that encourage board-level components to seriously consider spending more money. As a result, this research motivates social behavior members to contribute globally to the betterment of society
Dual Stage CMOS Operational Amplifier Design in Sky-Water 130nm Technology

A Two stage CMOS OPAMP with frequency compensation has been designed using open source Google’s SkyWater 130nm Technology. This OPAMP operates at 1.8V of Vdd single supply voltage. This circuit has been designed and simulated using eSim open source EDA tool developed by IIT Bombay. Pre-layout simulations of OPAMP gives 62dB of voltage gain with Unity gain bandwidth of 20MHz. Post-layout simulations were carried out using open source MAGIC tool and Ngspice. Post-layout simulations of OPAMP gives 55dB of voltage gain with Unity gain bandwidth of 120MHz with output slew rate of 38 V/µs. It is a low power OPAMP with power consumption of 54µW.
On the use of symbolic vibration data for robust structural health monitoring

Structural health monitoring is based on the development of reliable and robust indicators able to detect, locate, quantify or even predict damage. Studies related to damage detection in civil engineering structures are of interest to researches in this area. Indeed, the detection of structural changes likely to become critical can prevent the occurrence of major dysfunction associated with social, economic and environmental consequences. Recently, many researchers have focused on dynamic assessment as part of structural diagnosis. Most of the studied techniques are based on time or frequency domain analyses to extract information from modal characteristics or based on indicators built from those parameters. The main goal of this study relies on the application of symbolic data analysis coupled with classification methods to detect structural damage, especially using raw data (i.e. in situ measurements). Modal parameters, such as natural frequencies and mode shapes, are also considered in the analysis. In.
“Ptychoparioid” trilobites of the Harkless Formation and Mule Spring Limestone (Cambrian Series 2, Stage 4), Clayton Ridge, Nevada

Abstract. Early “ptychoparioid” trilobites are likely to play a crucial role in determining the currently unresolved phylogenetic relationships among the numerous Cambrian libristomate clades. However, such phylogenetic analyses are hindered by the fact that many species and genera of early “ptychoparioids” are known from very limited material and are typically defined only on cranidial features. Herein, we report new “ptychoparioid” assemblages from the Saline Valley Tongue, Harkless Formation at Clayton Ridge, Nevada. These middle to upper Dyeran Stage (Cambrian Series 2, Stage 4) assemblages contain well-preserved early “ptychoparioids” that are represented by articulated exoskeletons as well as isolated cranidia, rostral plates, librigenae, thoracic segments, and pygidia, which together provide morphological details for the complete or nearly complete exoskeleton of three new genera and four new species: Anebocephalus silverpeakensis n. gen. n. sp. ; Coenoides scholteni n. gen. n. sp. ; Harklessaspis rasettii n. gen. n. sp. ; and H. parvigranulosus n. gen. n. sp. Pending a formal phylogenetic analysis, it is deemed preferable to assign these taxa to new genera rather than to shoehorn them in to potentially ill-diagnosed existing genera. These new genera are compared to the Cambrian Series 2 taxa Crassifimbra and Eokochaspis, and the Miaolingian Series taxon Elrathina, which are similar in morphology and known from sclerites other than just cranidia. Also documented in this study are the “ptychoparioids” Crassifimbra walcotti, Cr. sp. A, Cr. sp. B, and “ptychoparioid” spp. A, B, C, and D from the Saline Valley Tongue and the overlying Mule Spring Limestone and lowermost Emigrant Formation.
Formulation and Evaluation of Floating Sustain Release Pellets of Anti Gout Drug

Objective: The objective of this investigation was to formulate and evaluate effervescent pellets of febuxostat to achieve sustain release effect. Place and Duration of Study: APMC College of Pharmaceutical education and research, Department of Pharmaceutics, Himatnagar-383001, between June 2019 and July 2021. Materials and Methods: The gastro retentive effervescent pellets of febuxostat were formulated using Sodium CMC and HPMC K4M and HPMCK15M as a sustain release polymer. Pellets were prepared by extrusion- spheronization technique using microcrystalline cellulose as spheronizing agent and sodium bicarbonate and citric acid as a gas forming agent for effervescent pellets. The pellets were characterized with respect to their floating lag time, total buoyancy time and % cumulative drug release. Results and Discussion: DSC study showed that there was no change in the melting endotherm of the drug and drug-polymers mixture which means drug and polymers were compatible with each other. The optimized formulation B14 exhibits a floating lag time 4.00±0.004 sec. and cumulative % drug release at 12th hour 99.58±0.02. Scanning electron microscopy photomicrograph revealed that the surface was rough and pellets were spherical shaped in nature. Conclusion: Febuxostat sustain release pellets was successfully formulated and evaluated as effervescent pellets with gas former agents and sustain release polymer HPMC K15.
Research Questions and Priorities for Pediatric Tuberculosis: A Survey of Published Systematic Reviews and Meta-Analyses

Background Advancing a research agenda designed to meet the specific needs of children is critical to ending pediatric TB epidemic. Systematic reviews are increasingly informing policies in pediatric tuberculosis (TB) care and control. However, there is a paucity of information on pediatric TB research priorities. Methodology. We searched MEDLINE, EMBASE, Web of Science, and the Cochrane Library for systematic reviews and meta-analyses on any aspect related to pediatric TB published between 2015 and 2021. We used the UK Health Research Classification System (HRCS) to help us classify the research questions and priorities. Findings. In total, 29 systematic reviews, with 84 research questions, were included in this review. The four most common research topics in the area of detection were 43.33% screening and diagnosis of TB, 23.33% evaluation of treatments and therapeutic interventions, 13.34% TB etiology and risk factors, and 13.34% prevention of disease and conditions and promotion of well-being. The research priorities focused mainly on evaluating TB diagnosis by improving yield through enhanced in specimen collection or preparation and evaluating of bacteriological TB diagnostic tests. Other topics of future research were developing a treatment for TB in children, assessing the use of IPT in reducing TB-associated morbidity, evaluating the prioritization of an IPT-friendly healthcare environment, and providing additional guidance for the use of isoniazid in the prevention of TB in HIV-infected children. Conclusion There is a need for more systematic reviews on pediatric TB. The review identified several key priorities for future pediatric TB research mainly in the domain of (1) “Detection, screening and diagnosis,” “Development of Treatments and Therapeutic Interventions,” and “Prevention of Disease and Conditions, and Promotion of Well-Being. ” These domains are very relevant in the research component of the roadmap towards ending TB in children. It also will serve as an additional action in the WHO End TB strategy.
Canine Stem Cell Conditioned Media Accelerates Epithelial Migration in the Canine Tympanic Membrane

Similar to skin, epithelia in the tympanic membrane (TM) regenerate and move toward the opening of the external ear canal, a process called epithelial migration (EM). EM is important for maintaining healthy ears because this process removes cerumen and debris. Therefore, increasing the rate of EM or TM regeneration could be very important for healthy ear maintenance and function. Stem cells or their conditioned media have been used in medical therapy in humans to increase the rate and efficacy of EM. The purpose of this study was to evaluate the ability of canine stem cell conditioned media to accelerate EM in canine TMs. Canine adipose tissue derived-mesenchymal stem cell conditioned media (cAD-MSCCM), and several cytokines related to keratinocyte growth or migration within the media were quantified using ELISA. Ink drops were placed on the TMs of four normal beagles. Then, cAD-MSCCM was applied weekly, a total of three times to the TMs of one ear, and nothing was applied to the other eye. The results showed a higher TM EM rate in the treatment group than in the control group (p < 0.05). No adverse events were recorded. These results suggest that the weekly application of cAD-MSCCM accelerates the TM EM rate.