Miracle-dz/UniFAR-FTUs huggingface dataset:
Comparative pathology and immunohistochemistry of Newcastle disease in domestic chicken (Gallus-gallus domesticus) and Alabio duck (Anas platyrhynchos Borneo)

Background: Newcastle disease is very pathogenic in chickens, whereas in ducks, the disease does not show any clinical symptoms. Aims: To compare the clinical symptoms features, pathological lesions, viral distribution, and apoptosis response caused by the Newcastle disease virus (NDV) in domestic chicken and Alabio duck. Methods: Forty domestic chickens and 40 Alabio ducks were separated into four groups: domestic chicken and Alabio duck treatment groups, where each was infected by NDV velogenic ducks/Aceh Besar_IND/2013/eoAC080721 in 106ELD50 dosage. The domestic chicken and Alabio duck control groups were each inoculated with Phosphate Buffer Saline. The infection route was intraorbital, 0.1 ml in volume. Symptoms were observed from day 1 until day 7 post-infection (PI). Necropsy was performed on days 1, 2, 3, 5, and 7 PI for organ collection. Results: Symptoms observed were disorders in the respiratory, gastrointestinal, and nervous systems, followed by 100% mortality in domestic chickens. In Alabio ducks, there were only depression and slight lethargy. The lesion in domestic chicken day 1 appeared by the lungs, thymus, Fabricius bursa, spleen, and kidney. On day 3 PI, lesions were also found in the heart, proventriculus, duodenum, and cecal tonsil. On days 5 and 7 PI, the trachea and brain lesions were found. In Alabio ducks, lesions were found in the lungs, thymus, spleen, and proventriculus on day 1. Afterward, on day 3, light lesions were found in the heart. On day 5, lesions were found in the trachea and brain; finally, on day 7, light lesions were only found in the thymus, spleen, and brain. Immunopositive reaction NDV in domestic chicken was highest in the proventriculus, duodenum, cecal tonsil, and lymphoreticular organs. In the Alabio duck, it was highest in the duodenum and cecal tonsil. The caspase-3 percentage in domestic chicken increased on day 3 PI; in Alabio ducks, on day 2 PI. Conclusion: Clinical symptoms and pathological lesions were faster and more severe in domestic chickens. The immunopositive reaction NDV in domestic chicken continued to increase, while in Alabio ducks, it decreased until the last observation day. Apoptosis percentage increased earlier in the Alabio duck than in domestic chicken.
Age-Friendly Cities in Latin America: A Human Ecological Framework

Despite the demographic aging of Latin America, the uptake of the WHO’s Age-Friendly Cities Framework remains extremely low, with the notable exceptions of Chile, Mexico and Brazil. We argue for a broader human ecological framework, which focuses on the macro, meso and micro levels, to better address the context, challenges and opportunities for age-friendly cities in the Latin American region. The WHO’s age-friendly city domains are primarily at the meso (community) scale, with a focus on built environment, services and participation. We call for more attention to be paid to the macro policy scale to address concerns regarding migration, demography and social policy context. More attention also should be given to the micro scale to recognize the critical role of family and informal care supports. It is possible that the WHO domains are the result of a design bias, with Global North settings in mind for their development. We find the domains of UNICEF’s Child-Friendly Cities Initiative, which give more attention to the realities of the Global South, helpful to broaden the WHO’s Age-Friendly Cities Framework.
Neurobiological Link between Stress and Gaming: A Scoping Review

Research on video gaming has been challenged by the way to properly measure individual play experience as a continuum, and current research primarily focuses on persons with gaming disorder based on the diagnostic criteria established in relation to substance use and gambling. To better capture the complexity and dynamic experience of gaming, an understanding of brain functional changes related to gaming is necessary. Based on the proinflammatory hypothesis of addiction, this scoping review was aiming to (1) survey the literature published since 2012 to determine how data pertinent to the measurement of stress response had been reported in video gaming studies and (2) clarify the link between gaming and stress response. Eleven studies were included in this review, and the results suggest that gaming could stimulate a stress-like physiological response, and the direction of this response is influenced by an individual’s biological profile, history of gaming, and gaming content. Our findings highlight the need for future investigation of the stress-behaviour correlation in the context of gaming, and this will assist in understanding the biological mechanisms underlying game addiction and inform the potential targets for addiction-related proinflammatory research.
A narrative review: evaluation and surgical management of persistent and recurrent urinary incontinence after previous surgical treatment

Background and Objective Urinary incontinence after prostate treatment is associated with significant morbidity and impact on quality of life. Stress urinary incontinence can be treated by insertion of a urethral sling or artificial urinary sphincter. Persistent or recurrent urinary incontinence after such treatment can be frustrating and require specific evaluation and approach to management to optimize chance of successful outcomes and patient satisfaction whilst avoiding further patient morbidity. The aim of this review is to outline the evaluation and management of persistent and recurrent urinary incontinence in men after previous surgical treatment for stress urinary incontinence by way of narrative review. Methods A literature review was performed using PubMed, MEDLINE, and Google Scholar between 2010 to 2023. The search strategy included the following MeSH terms: device, men, urinary incontinence, persistence, recurrence, and revision. A total of 140 English-language articles were identified and reviewed; 68 articles were considered relevant to the aims and the findings have been outlined in this narrative review. Key Content and Findings There are many approaches currently practiced by surgeons in continence revision surgery. There is not clear consensus regarding optimum revision strategy for persistent and recurrent incontinence post urethral sling and artificial urinary sphincter insertion. Whilst small observational studies have reviewed different surgical approaches, there is a paucity of high volume comparative data from which to draw conclusions. However, there have been recent studies enabling a paradigm shift in the understanding of incontinence post artificial urinary sphincter insertion that may lead to improved revision strategies in future. Conclusions There are various surgical modalities used to manage incontinence following urethral sling and artificial urinary sphincter insertion. There is currently no clear consensus on the optimal surgical technique for persistent or recurrent urinary incontinence after surgery. Further comparative studies would be beneficial to help guide surgeons as to which revision approaches would be suitable for select patients.
Permanent fillers—What is their role

With the growing cosmetic industry, there have been numerous advancements in nonsurgical interventions including the use of permanent dermal filler injections. Permanent fillers are relatively novel in clinical use when compared to temporary and semi‐permanent fillers. The only FDA‐approved, non‐biodegradable permanent filler uses polymethylmethacrylate (PMMA) microspheres. PMMA is suspended in bovine collagen and lidocaine solution for injection, absorbed by the body, and replaced overtime by collagen. ArteFill® was the first FDA approved permanent filler in 2005 for correction of nasolabial folds, with studies demonstrating rejuvenation for up to five years, trumping its predecessors in longevity. A decade later with rebranding, Bellafill® was indicated for correction of nasolabial fold and atrophic acne scars.
Precision Medicine in Oral Health and Diseases: A Systematic Review

Precision medicine (PM) is personalized medicine that can develop targeted medical therapies for the individual patient, in which “omics” sciences lead to an integration of data that leads to highly predictive models of the functioning of the individual biological system. They enable rapid diagnosis, assessment of disease dynamics, identification of targeted treatment protocols, and reduction of costs and psychological stress. “Precision dentistry” (DP) is one promising application that need further investigation; the purpose of this paper is therefore to give physicians an overview of the knowledge they need to enhance treatment planning and patient response to therapy. A systematic literature review was conducted on the PubMed, Scopus, and Web of Science databases by analyzing the articles examining the role of precision medicine in dentistry. PM aims to shed light on cancer prevention strategies, by identifying risk factors, and on malformations such as orofacial cleft. Another application is pain management by repurposing drugs created for other diseases to target biochemical mechanisms. The significant heritability of traits regulating bacterial colonization and local inflammatory responses is another result of genomic research, and is useful for DP in the field of caries and periodontitis. This approach may also be useful in the field of orthodontics and regenerative dentistry. The possibility of creating an international network of databases will lead to the diagnosis, prediction, and prevention of disease outbreaks, providing significant economic savings for the world’s health care systems.
Current Concepts of Fracture-Related Infection

Currently, fracture-related infection (FRI) still represents great challenges in front of orthopaedic surgeons, despite great advances that have been achieved regarding its diagnosis and treatment. Although both FRI and prosthetic joint infection (PJI) belong to osteoarticular infections and share similarities, FRI displays unique characteristics. Diagnosis of FRI is sometimes difficult owing to the nonspecific symptoms, and treatment is usually tricky, with a high risk of infection recurrence. In addition, the long disease course is associated with a significantly elevated risk of disability, both physically and psychologically. Moreover, such a disorder still poses heavy economic burdens to the patients, both personally and socially. Therefore, early diagnosis and reasonable treatment are the key issues for increasing the cure rate, decreasing the risks of infection relapse and disability, and improving the life quality and prognosis of the patients. In this review, we summarized the present concepts regarding the definition, epidemiology, diagnosis, and treatment of FRI.
Effectiveness of Caregiver-Provided Individual Cognitive Interventions in Older Adults with Dementia

Background: In a society increasingly committed to promoting an active life in the community, new resources are needed to respond to the needs of citizens with Alzheimer’s disease and other forms of dementia. The potential of several individual cognitive interventions to be provided by caregivers has been explored in the literature. Objective: To synthesize the best available evidence on the effectiveness of caregiver-provided individual cognitive interventions in older adults with dementia. Methods: Systematic review of experimental studies on individual cognitive interventions for older adults with dementia. An initial search of MEDLINE and CINAHL was undertaken. Another search for published and unpublished studies was performed on major healthcare-related online databases in March 2018 and updated in August 2022. This review considered studies that included older adults with dementia, aged 60 years and over. All studies that met the inclusion criteria were assessed for methodological quality using a JBI standardized critical appraisal checklist. Data were extracted using a JBI data extraction form for experimental studies. Results: Eleven studies were included: eight randomized controlled trials and three quasi-experimental studies. Caregiver-provided individual cognitive interventions had several beneficial effects in cognitive domains, including memory, verbal fluency, attention, problem-solving, and autonomy in activities of daily living. Conclusion: These interventions were associated with moderate improvements in cognitive performance and benefits in activities of daily living. The findings highlight the potential of caregiver-provided individual cognitive interventions for older adults with dementia.
Addressing the Continuing Quandary of Theory in Housing Research: A Systematic Review of Contemporary Literature

ABSTRACT The housing studies field has been critiqued since the 1980s for under-engagement with theory. In this paper, we present the findings of a systematic literature review that investigates the extent to which contemporary housing scholarship engages with theory. By reviewing all research papers published in three leading housing journals in 2019 and 2020, we identify references to theory and evaluate the extent of engagement with theory. In total, 313 papers were reviewed to assess current theoretical frontiers in housing studies. We conclude that the theory-scape of housing research is more complex and nuanced than previously depicted, with contemporary scholarship engaging meaningfully with diverse theoretical frameworks of both “general” and “housing-specific” application. Our findings illuminate how housing studies is growing not only as an interdisciplinary field, but also as a well-theorized one.
Relational Collusion in the Colombian Electricity Market

Under collusion, firms deviate from current profit maximization in anticipation of future rewards. As current profit maximization places little restrictions on firms’ pricing behaviour, collusive conduct is hard to infer. We show that bids from certain firms in the Colombian wholesale electricity market collapsed immediately after the announcement, and before the implementation, of a reform that potentially made collusion harder to sustain. After ruling out confounders, we uncover how the cartel functioned and how firms may have communicated. Calibrating the dynamic enforcement constraint confirms that collusion was sustainable before, but not after, the reform. The conclusions discuss policy implications.
Risk of Interprosthetic Femur Fracture Is Associated with Implant Spacing—A Biomechanical Study

Background: Ipsilateral revision surgeries of total hip or knee arthroplasties due to periprosthetic fractures or implant loosening are becoming more frequent in aging populations. Implants in revision arthroplasty usually require long anchoring stems. Depending on the residual distance between two adjacent knee and hip implants, we assume that the risk of interprosthetic fractures increases with a reduction in the interprosthetic distance. The aim of the current study was to investigate the maximum strain within the femoral shaft between two ipsilateral implants tips. Methods: A simplified physical model consisting of synthetic bone tubes and metallic implant cylinders was constructed and the surface strains were measured using digital image correlation. The strain distribution on the femoral shaft was analyzed in 3-point- and 4-point-bending scenarios. The physical model was transferred to a finite element model to parametrically investigate the effects of the interprosthetic distance and the cortical thickness on maximum strain. Strain patterns for all parametric combinations were compared to the reference strain pattern of the bone without implants. Results: The presence of an implant reduced principal strain values but resulted in distinct strain peaks at the locations of the implant tips. A reduced interprosthetic distance and thinner cortices resulted in strain peaks of up to 180% compared to the reference. At low cortical thicknesses, the strain peaks increased exponentially with a decrease in the interprosthetic distance. An increasing cortical thickness reduced the peak strains at the implant tips. Conclusions: A minimum interprosthetic distance of 10 mm seems to be crucial to avoid the accumulation of strain peaks caused by ipsilateral implant tips. Interprosthetic fracture management is more important in patients with reduced bone quality.
Seed Nano-Priming with Calcium Oxide Maintains the Redox State by Boosting the Antioxidant Defense System in Water-Stressed Carom (Trachyspermum ammi L.) Plants to Confer Drought Tolerance

This paper explores the potential of nano seed priming with calcium oxide nanoparticles in maintaining the redox status in carom (Trachyspermum ammi L.) plants by modulating non-enzymatic antioxidants and enzymatic antioxidants. Calcium oxide nanoparticles were prepared in four testing regimes comprising 25, 50, 75, and 100 ppm along with the control treatment of 0 ppm (distilled water). Priming was performed by soaking the carom seeds in the aerated water, and plants were grown under split plots corresponding to drought and water. Seed priming with 75 ppm CaONPs reduced hydrogen peroxide, malondialdehyde contents and electrolyte leakage by 23.3%, 35.9% and 31.6%, respectively, in the water-stressed carom plants. The glutathione s-transferase, superoxide dismutase and peroxidase functions improved under water stress by 42.3%, 24.1% and 44.8%, respectively, in the carom plants raised through 100 ppm primed seeds with CaO_NPs. Priming induced better Ca2+ signaling, which affected the enzymes of the ascorbate glutathione cycle, enabling them to maintain redox status in the carom plants exposed to drought stress. The morpho-agronomic traits of carom plants in terms of number of umbels, hundred seeds weights, shoot and root length and biomass improved significantly upon seed priming treatments. Seed priming with CaO_NPs is a viable strategy to combat reactive oxygen species-mediated damages in the carom plants.
Measurement of platelet count with different anticoagulants in thrombocytopenic patients and healthy subjects: accuracy and stability over time

The accuracy of platelet count measurement is important for the diagnosis and management of thrombocy-topenia, which is defined as platelet count <150×109/L,[1][1] although new age- and sex-specific reference intervals should be adopted. [2][2] An exception is immune thrombocytopenia (ITP), which is
Decreased Sensitivity of Grassland Spring Phenology to Temperature on the Tibetan Plateau

Spring phenology is a critical indicator to characterize vegetation dynamics and their responses to climate change. Spring phenology on the Tibetan Plateau (TP) has received extensive attentions as it has experienced one of the most rapid warmings. Warming-induced advancement of spring phenology has been revealed by many studies, however, the underlying mechanisms remain obscure. In this article, we derived the start of growing season (SOS) from the satellite solar-induced chlorophyll fluorescence (SIF) and investigated the spatial and temporal variations of SOS over grasslands on the TP during 2001–2020. The temperature sensitivity (St) of SOS was then analyzed, i.e., the slope of a linear regression between the advanced SOS and preseason air temperature. Results showed an average advanced trend of 0.29 days per decade of SOS, although not statistically significant. Spatially, grasslands in eastern TP showed an earlier trend of SOS whilst those in western TP showed a later trend of SOS. The spatial distribution of St was much more affected by precipitation and air temperature, i.e., a 1 mm decrease of precipitation and 1 °C warming incur a decrease in St of 0.02 and 0.54 day/°C, respectively. Temporally, St showed a significant decrease with an average speed of 0.14 day/°C per year during 2001–2020, and the climate controllers show a high spatial heterogeneity. These findings improved our understanding of grasslands spring phenology responses to warming and help us clarify future global water and energy cycles.
Examining the role of social media and mobile social networking applications in socio-political contestations in Nigeria

Social media platforms continue to flourish as practices encompassing them become deeply embedded in many cultures. As more people embrace social media platforms, their affordances and opportunities are leading to improved communication, and helping hold authorities to account. To further scrutinize the importance of these platforms, this study interrogates the role of digital media in socio-political contestations in Nigeria by examining the media used to mobilize, coordinate, and document the 2020 #EndSARS protests in Nigeria. Analyses of survey data collected in 2020 during the protests in Lagos and Port Harcourt, Nigeria (N = 391) show that demonstrators who were 30 years and older and used WhatsApp and Facebook to learn about the protests as well as coordinate their participation in the protests are more likely to report participating on the first day of the protests than protesters who are younger than 30 and used other media platforms. Findings further illustrate that digital enthusiasm facilitated by hedonic-experiential and epicurean communication on WhatsApp and Facebook eventuated a process of emotional contagion through connective repertoires that created propitious emotional conditions for mass collective protest actions. Finally, the article discusses how the use of WhatsApp and Facebook gave protesters strategic communicative power during the protests.
High‐efficiency nanowire light‐emitting diodes for augmented reality and virtual reality displays

Through 3D dipole cloud model, RGB (red, green, and blue) nanowire light‐emitting diode (LED) structures are geometrically optimized to exhibit a narrower radiation pattern, weaker angular color shift, and higher optical efficiency. In comparison with micro‐LEDs whose external quantum efficiency is dependent on the mesa size, these RGB nanowire LEDs are more efficient than micro‐LEDs when the chip size is below 20, 80, and 10 μm, respectively. As a result, nanowire LED is a promising candidate for augmented reality and virtual reality displays where high‐resolution density and efficient directional light emission are desired.
The gendered effect of an overwork climate and high personal standards for work–home conflict during the pandemic

Although working from home and various other forms of flexible work are often presented as measures to strengthen work–life balance, research depicts a less optimistic picture. Previous research has shown that the impact of telework on work–home conflict is controversial, depending on various factors that are also frequently gender-specific. In this study, the authors evaluate and compare the effects of external expectations (i.e., an organizational overwork climate) and internal expectations (i.e., high personal standards) on changes in work–home conflict between working men and women during the COVID-19 pandemic in Lithuania. Both types of expectations were associated with difficulties reconciling work and private life. Due to their interactions with stereotypical gender roles, organizational expectations encouraging overtime work had a more pronounced effect on male employees. Results suggest that an overwork climate within organizations is a problem not only for employees’ well-being but also poses a risk to gender equality in work and private life.