Miracle-dz/UniFAR-FTUs huggingface dataset:
Effectiveness of kinesio taping in bicipital tendinitis treatment: A randomized controlled trial

DOI: 10.4328/ACAM.20124 Received: 2020-02-01 Accepted: 2020-03-23 Published Online: 2020-04-07 Corresponding Author: Tomris Duymaz, Istanbul Bilgi University, Faculty of Health Sciences, Physiotherapy and Rehabilitation, Pir Hüsamettin Sk No:20 34440 Beyoğlu, Istanbul/ Turkey. E-mail: tomrisduymaz@gmail.com GSM: +90 5446302676 Corresponding Author ORCID ID: https://orcid.org/0000-0003-0917-2098 Abstract Aim: Biceps tendinitis is characterized by inflammation of the biceps long head, and treatment options include various conservative and surgical methods. Kinesiotaping (KT) has benefited in reducing pain and providing motor control in various shoulder disorders. The aim of this study is to investigate the effectiveness of KT application in patients with biceps tendinitis in terms of pain, pain threshold, upper extremity functionality level and quality of life. Materials and Methods: Eighty patients with biceps tendinitis were divided into two groups randomly, each comprising 40 patients. The study group received KT with an exercise program, the control group received an exercise program only. Preand post-treatment evaluations were conducted. Pain threshold was evaluated with a digital algometer, pain severity with visual analog scale (VAS), functional capacity with the disabilities of the arm, shoulder and hand score (Q-DASH) and quality of life with Nottingham Health Profile (NHP). Results: The mean duration of the symptoms was 4.5 months and the mean age was 45.80±8.48 years. Pain intensity decreased during activity (p<0.001) and pain thresholds increased (p<0.001) in the KT group. Q-DASH scores improved significantly in patients in the KT group, there was a less significance in the control group (p<0.001, 0.043). The NHP scores except social isolation improved in all sub-parameters of the KT group and there was no significance in control group (p>0.05, 0.003, 0.012, 0.023, 0.225, 0.035, 0.029, 0.006). Discussion: KT application decreases pain and increases the functional capacity level and can also play a role in improving the general quality of life in biceps tendinitis treatment.
A Comparison of Conservation Reserve Program Habitat Plantings with Respect to Arthropod Prey for Grassland Birds

Abstract The Conservation Reserve Program (CRP) was designed to reduce soil erosion and curb agricultural overproduction by converting highly erodible agricultural land to various forms of perennial habitat. It has had an incidental benefit of providing habitat for wildlife and has been beneficial in reversing population declines of several grassland bird species. However, the mechanisms behind these reversals remain unknown. One such mechanism may be differences in food availability on CRP vs. non-CRP land or between different types of CRP. The influence of CRP habitat type on the abundance of arthropod prey used by grassland birds has not been previously explored. We compared the abundance and diversity of arthropods among four CRP habitat types in Texas [replicated plots of exotic lovegrass (Eragrostis curvula), Old World bluestem (Bothriochloa ischaemum), mixed native grasses with buffalograss (Buchloë dactyloides) and mixed native grasses without buffalograss] and native shortgrass prairie. Attention was focused on adult and juvenile spiders (Order Araneae), beetles (Coleoptera), orthopterans (Orthroptera: grasshoppers and crickets) and lepidopterans (Lepidoptera: butterflies and moths), as these taxa are the primary prey items of grassland birds during the breeding season. Arthropod diversity and abundance were higher on indigenous prairie compared to CRP, reflecting differences in vegetative diversity and structure, but there were no differences in arthropod richness or abundance among CRP types. These results indicate that, although CRP is not equivalent to native prairie in terms of vegetation or arthropod diversity, CRP lands do support arthropod prey for grassland birds. More direct assays of the survivorship and fitness of birds on CRP compared to native shortgrass prairie are clearly warranted.
Estimating density of Kirk’s dik‐dik (Madoqua kirkii Günther), impala (Aepyceros melampus Lichtenstein) and common zebra (Equus burchelli Gray) at Mpala, Laikipia District, Kenya

This study compares two methods of estimating the density of three ungulate species: Kirk’s dik-dik, impala and common zebra, in a dry savannah ecosystem. Fixed strip width and distance sampling involving direct animal counts were used in parallel, and tested for bias and precision in two habitats. Distance sampling was the method that achieved a better balance between accuracy and precision. The differences in sightability of ungulates, according to body size, colour and habitat characteristics, are taken into account by the distance sampling method, but not by the strip method, which produced, what we suspect are, underestimates of animal density. Resume Cette etude compare deux methodes pour estimer la densite de trois especes d’ongules : le dik-dik de Kirk, l’impala et le zebre de Burchell, dans un ecosysteme de savane seche. On a utilise en parallele l’echantillonnage par largeur de bande fixe et celui a distance perpendiculaire, impliquant le comptage direct des animaux, et nous avons teste les biais qu’ils induisent et leur precision dans deux habitats. L’echantillonnage a distance perpendiculaire fut la methode qui a obtenu le meilleur equilibre entre exactitude et precision. Les differences de visibilite des ongules, selon la taille corporelle, la couleur et les caracteristiques de l’habitat, sont prises en compte par la methode a distance mais pas par la methode par bande qui entraine, nous le suspectons, des sous-estimations de la densite animale.
Homogeneity in subject-verb concord in South African English

Abstract This paper explores the strategies employed by speakers of South African English for subject-verb concord using a large-scale methodology. It is argued that there is a complex interplay between broad types of agreement (e.g., syntactic vs notional agreement) and specific strategies for agreement (e.g., agreement with head noun vs ‘attraction’ agreement with the linearly closest noun). It is demonstrated that a particular type of notional agreement, namely ‘Atomic-Homogeneous’ agreement plays the largest role in South African English; although other types of agreements are also present in the data set. Since this type of agreement has not been widely reported on in the literature on American and British English, it may be that South African English represents a departure from agreement in these varieties. The paper also demonstrates the viability of large-scale methodologies for this type of research.
Alkalinity determination by potentiometry - intercalibration using three different methods

Seawater was sampled from different depths in the North Atlantic Ocean (Canary Islands region) and distributed among three different labs for the determination of titration alkalinity. Analysis was performed by potentiometric methods, involving titration in a closed cell, titration in an open cell and a two end-point acid addition method. The precision, which is the sample reproducibility taken from the mean standard deviation for replicate measurements, was between 0.45 and 0.90 µmol kg(-1) for the individual labs. Accuracy, here taken as the deviation for the values of a lab from the mean of all three, was mostly below 1 µmol kg(-1) and never exceeded 0.1% of the sample value. Mean standard deviation for all labs and all samples was 0.87 µmol kg(-1), once the individual methods were calibrated using certified reference material (CRM). Without CRM calibration, the mean standard deviation would increase to 2.8 µmol k(-1). The conclusion is that current high precision methods for alkalinity measurements calibrated with CRMs are able to reach similar accuracy as the measurement of total dissolved inorganic carbon by coulometry and therefore allow for the precise determination of the oceanic carbon dioxide system by using the two measured parameters.
Systematic Literature Review of Randomized Trials Comparing Antithrombotic Therapy Following Revascularization Procedures in Patients With Peripheral Artery Disease

A systematic literature review was conducted to identify and summarize the clinical efficacy and safety of available antithrombotic therapies after peripheral endovascular or surgical revascularization in patients with peripheral artery disease (PAD). Five databases were searched using free-text and Emtree/Mesh terms for PAD, randomized controlled trials (RCTs), and antithrombotic therapies of interest (ie, single antiplatelet therapy, dual antiplatelet therapy, and vitamin K antagonists). Randomized controlled trials were eligible for inclusion if they assessed the risk of thrombotic events (ie, myocardial infarction, ischemic stroke, cardiovascular death, limb ischemia, or limb amputation) or safety profile (ie, minor, moderate, major, or fatal bleeding events) after revascularization. In total, 16 RCTs were identified. Only a few studies reported on treatment effects of the investigated therapies. Myocardial infarction, ischemic stroke, cardiovascular death, and amputation were reported in up to 2.3%, 2.3%, 5.6%, and 7.3% of patients, respectively. Bleeding events were observed in up to 8.4% (major) and 1.5% (fatal) of patients. Despite available treatments, patients with PAD undergoing revascularization remain at risk of thrombotic events. There is a need for new treatments that will help to optimize care for patients with symptomatic PAD undergoing revascularization.
A three‐tiered integrative analysis of transcriptional data reveals the shared pathways related to heart failure from different aetiologies

Heart failure (HF) is the end stage of most heart disease cases and can be initiated from multiple aetiologies. However, whether the molecular basis of HF has a commonality between different aetiologies has not been elucidated. To address this lack, we performed a three‐tiered analysis by integrating transcriptional data and pathway information to explore the commonalities of HF from different aetiologies. First, through differential expression analysis, we obtained 111 genes that were frequently differentially expressed in HF from 11 different aetiologies. Several genes, such as NPPA and NPPB, are early and accurate biomarkers for HF. We also provided candidates for further experimental verification, such as SERPINA3 and STAT4. Then, using gene set enrichment analysis, we successfully identified 19 frequently dysregulated pathways. In particular, we found that pathways related to immune system signalling, the extracellular matrix and metabolism were critical in the development of HF. Finally, we successfully acquired 241 regulatory relationships between 64 transcriptional factors (TFs) and 17 frequently dysregulated pathways by integrating a regulatory network, and some of the identified TFs have already been proven to play important roles in HF. Taken together, the three‐tiered analysis of HF provided a systems biology perspective on HF and emphasized the molecular commonality of HF from different aetiologies.
Immediate histologic correlation in women with atypical squamous cells of undetermined significance cytology and positive high‐risk HPV: A retrospective review of 6000 cases in a large academic women's hospital

Previous studies of the histologic correlation in women who have atypical squamous cells of undetermined significance cytology (ASC‐US) and are positive for high‐risk human papillomavirus (hrHPV+) have predominantly utilized the Hybrid Capture 2 (HC2) test, whereas the use of other US Food and Drug Administration (FDA)‐approved methods is relatively limited.
Inorganic Arsenic Exposure Decreases Muscle Mass and Enhances Denervation-Induced Muscle Atrophy in Mice

Arsenic is a toxic metalloid. Infants with a low birth-weight have been observed in areas with high-level arsenic in drinking water ranging from 463 to 1025 μg/L. A distal muscular atrophy side effect has been observed in acute promyelocytic leukemia patients treated with arsenic trioxide (As2O3) for therapy. The potential of As2O3 on muscle atrophy remains to be clarified. In this study, the myoatrophic effect of arsenic was evaluated in normal mice and sciatic nerve denervated mice exposed with or without As2O3 (0.05 and 0.5 ppm) in drinking water for 4 weeks. We found that both 0.05 and 0.5 ppm As2O3 increased the fasting plasma glucose level; but only 0.5 ppm arsenic exposure significantly decreased muscle mass, muscle endurance, and cross-sectional area of muscle fibers, and increased muscle Atrogin-1 protein expression in the normal mice. Both 0.05 and 0.5 ppm As2O3 also significantly enhanced the inhibitory effects on muscle endurance, muscle mass, and cross-sectional area of muscle fibers, and increased the effect on muscle Atrogin-1 protein expression in the denervated mice. These in vivo results suggest that inorganic arsenic at doses relevant to humans may possess myoatrophic potential.
Influence of Needs and Experiences of Haemato-Oncology Patients on Acceptability of a Telephone Intervention for Support and Symptom Management: A Qualitative Study

Healthcare technologies are increasingly used to address the unmet needs of patients with cancer; however new service developments must be acceptable to patients. The objective of this study was to determine the unmet needs of haemato-oncology patients and their influence on the perceived acceptability and participation in a telephone intervention delivering. A qualitative study was designed interviewing 20 participants having received the intervention. Data were analysed inductively and deductively using Framework Analysis. Three core themes emerged: (1) fluctuations in emotional distress and coping across the cancer trajectory with evidence of adaptive and maladaptive coping; (2) potential deficits in patient support, continuity of care and information provision; and (3) intervention acceptability analysis underpinned by the Theoretical Framework of Acceptability showed acceptability was influenced by participants’ subjective illness contexts and unmet needs. This work contributes to understanding of personal context as a determinant of intervention acceptability in order to enhance implementation strategies.
Hepatitis C Virus Influences HIV-1 Viral Splicing in Coinfected Patients

Coinfection with hepatitis C virus (HCV) influences HIV reservoir size. However, it is unknown whether this coinfection also induces a higher provirus transcription. Viral transcription is promoted by synergy between cellular factors such as NF-κB and the viral regulator Tat. The impact of HCV coinfection on HIV provirus transcription was analyzed in resting (r)CD4 T+ cells (CD3+CD4+CD25-CD69-HLADR-) and rCD4 T cells-depleted PBMCs (rCD4 T- PBMCs) from a multicenter cross-sectional study of 115 cART-treated HIV patients: 42 HIV+/HCV+ coinfected individuals (HIV+/HCV+), 34 HIV+ patients with HCV spontaneous clearance (HIV+/HCV−) and 39 HIV patients (HIV+). Viral transcription was assessed in total RNA through the quantification of unspliced, single spliced, and multiple spliced viral mRNAs by qPCR. Linear correlations between viral reservoir size and viral splicing were determined. A 3-fold increase of multiple spliced transcripts in rCD4 T+ cells of HIV+/HCV+ patients was found compared to HIV+ individuals (p < 0.05). As Tat is synthesized by multiple splicing, the levels of Tat were also quantified in these patients. Significant differences in single and multiple spliced transcripts were also observed in rCD4 T- PBMCs. Levels of multiple spliced mRNAs were increased in rCD4 T+ cells isolated from HIV+/HCV+ subjects, which could indicate a higher Tat activity in these cells despite their resting state.
Discerning adaptive value of seasonal variation in preen waxes : comparative and experimental approaches

Birds possess a preen (or uropygial) gland on their rump that secretes substances which are preened into the plumage, and which are probably essential for plumage maintenance. Secretions of the uropygial gland consist predominantly of wax-esters: fatty acids esterified to alcohols. These wax components vary in chain length and in degree and location of branching of the carbon skeletons, resulting in complex mixtures of many different wax esters in preen gland secretions. We have found that shorebirds show pronounced seasonal changes in the composition of their preen waxes. Between arrival on and departure from breeding grounds, their usual monoester wax at winter quarters changes dramatically to a more complex diester- based wax, which is maintained throughout the breeding season. The diesters have higher molecular weights and probably different physical properties than monoesters, and the secretion and use of diesters rather than monoesters may entail specific costs and benefits. We discuss how natural and sexual selection could explain the evolution of compositional shifts in preen waxes and outline possible approaches for future research.
Putative Otobius megnini-associated clinical signs in horses in South Africa (2012–2018)

Otobius megnini has been associated with certain clinical conditions in horses in both California and Mexico. A number of cases similar to those described previously have been identified by the author in South Africa. This case report summarises these cases to demonstrate that the clinical condition occurs readily in South Africa and may be increasing in occurrence. The disease has minimal coverage in the literature making it more likely that a veterinarian, unfamiliar with the disease, will miss the diagnosis. The author would like to make veterinarians aware of this as a potential differential diagnosis. This study is a retrospective review of clinical data. Clinical records of patients with similar clinical signs and treatment were reviewed and grouped together as relevant cases for this case report. Ten cases of O. megnini associated neuromuscular dysfunction are reported, suggesting a link between the occurrence of the tick and the clinical condition. Clinical signs include third eyelid prolapse, localised muscle fasciculations, elevated heart rate and limb stamping. Serum chemistry changes commonly show increased aspartate aminotransferase and creatine kinase enzymes activities. The occurrence of the ticks within South Africa and the increasing number of cases presented demonstrate the need for more investigation into the pathophysiology of this condition.
Most Wanted

On the standard, neo-Gricean view, most is semantically lower bounded but may give rise to the meaning "not all" through scalar implicature (Horn (1972)). More recent proposals have claimed that most does not generate a scalar implicature but is semantically both lower and upper bounded (Ariel (2004; in press)). In this article, we investigate the interpretation of most experimentally to evaluate these competing semantic and pragmatic accounts. We focus on a comparison of most and half because, on the classical view, half and other exact determiners should admit bilateral interpretations more readily than the upward-oriented most (Horn (in press)); however, no such difference should exist if most is both lower and upper bounded. We find that (i) in nonbiasing contexts, adults are more likely to treat most as being compatible with all than half ; (ii) a similar asymmetry emerges in children's interpretations of the two determiners; and (iii) adults adjust the higher boundary of the interpretation of most according to context-driven expectations. Taken together, these results support the classical, lower bounded, semantic analysis of most over recent revisions. Our findings also raise important issues about children's initial conjectures about scalar quantifiers and the development of the semantics-pragmatics interface.
Changes in RT‐PCR test results and symptoms during the menstrual cycle of female individuals infected with SARS‐CoV‐2: Report of two cases

The implications of the menstrual cycle for disease susceptibility, development, and severity of acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) infection are largely unknown. Here, we describe two women infected with SARS‐CoV‐2 whose real‐time reverse transcriptase‐polymerase chain reaction (RT‐PCR) test results and symptoms changed during the menstrual cycle. The first patient developed a fever on the first day of her menstrual period, and again on the first day of her next menstrual period after hospital discharge. RT‐PCR test results were positive during the first menstrual period before admission, but turned negative during hospitalization, and then were positive again during the second menstrual period after hospital discharge. Another one also developed a fever again on the first day of her menstrual period after hospital discharge. RT‐PCR test results were negative before admission and during hospitalization, but turned positive during the first menstrual period after hospital discharge. The cases indicate sex hormones may play an important role in SARS‐CoV‐2 infection. For women with history of exposure to SARS‐CoV‐2, the management protocol should include assessment of the menstrual status.
Kinetics of viral load and antibody response in relation to COVID-19 severity.

The SARS-CoV-2 is the causative agent for COVID-19 pneumonia. Little is known about the kinetics, tissue distribution, cross-reactivity and neutralization antibody response in COVID-19 patients. Two groups of RT-PCR confirmed COVID-19 patients were enrolled in this study, including 12 severe patients in ICUs who needed mechanical ventilation and 11 mild patients in isolation wards. Serial clinical samples were collected for laboratory detection. Results showed that most of the severe patients had viral shedding in a variety of tissues for 20~40 days post onset of disease (8/12, 66.7%); while the majority of mild patients had viral shedding restricted to the respiratory tract and had no detectable virus RNA after 10 days post-onset (9/11, 81.8%). Mild patients showed significantly lower IgM response compared with that of the severe group. IgG responses were detected in most patients in both severe and mild groups at 9 days post onset and remained high level throughout the study. Antibodies cross-reactive to SARS-CoV and SARS-CoV-2 were detected in COVID-19 patients but not in MERS patients. High-levels of neutralizing antibodies were induced after about 10 days post onset in both severe and mild patients which were higher in the severe group. SARS-CoV-2 pseudotype neutralization test and focus reduction neutralization test with authentic virus showed consistent results. Sera from COVID-19 patients, but not convalescent SARS and MERS patients inhibited SARS-CoV-2 entry. Anti-SARS-CoV-2 S and N IgG level exhibited moderate correlation with neutralization titers in patients' plasma. This study improves our understanding of immune response in human after SARS-CoV-2 infection.