Miracle-dz/UniFAR-FTUs huggingface dataset:
STATISTICAL STUDIES OF SURFACE LATENT HEAT FLUX AS A PRE EARTHQUAKE PRECURSOR IN SEISMOLOGI.

The affiliation between variations in surface latent heat flux (SLHF) and ocean unstable activity has been a classy issue of recent seismologic studies. So far, there are 2 issues, the way to determine the abnormal SLHF variations from troublesome background signals and the way to make sure that the irregularity outcome from unstable activity. During this paper, we have a tendency to planned four adjustable parameters for identification, classified the affiliation and analyze SLHF changes many months before six ocean unstable activities by using daily SLHF information. Besides, we have a tendency to additionally quantitatively value the future affiliation between unstable activity and SLHF anomalies for the six study areas over a twenty amount of period preceding every unstable activity. The results suggest: (1) before the South Sandwich Islands, Papua, Samoa and Haiti unstable activity, the SLHF variations on top of their individual background levels have comparatively low amplitudes and are troublesome to be thought-about as prophetical anomalies; (2) once removing the bunch result, most of the anomalies before these six unstable activity are not temporally connected to any unstable activity in every study space in time sequence; (3) for every case, apart from Haiti, over part of studied unstable activity that were cheap even devastating unstable activity (Mw = 5.3) had no prophetical variations in SLHF; and (4) the association between SLHF and unstable activity depends for the most part on info correctness and parameter settings. Before any application of SLHF information on unstable activity prediction, we advise that anomaly distinctive standards ought to be established supported future regional analysis to eliminate is graciousness. What is more, alternative factors which can end in SLHF variations additionally ought to be fastidiously thought-about. Index Terms SLHF, unstable activity, precursors, satellite, radiation.
The Association of Pancreatic Cancer and PALB2 Gene Mutations in the Turkish Population

Pancreas cancer (PC) is generally diagnosed in the advanced stage and is cancer with poor diagnosis. The data of Globocan in 2018 showed that the worldwide incidence rate of pancreas cancer was 2.5, with a ranking of 12 among the other cancers. The worldwide mortality rate is 94.2%. Pancreas cancer has a similar incidence and mortality rate in men and women. The Turkish data of pancreas cancer are compatible with worldwide data, and PC is the 9th most frequently occurring cancer, and the mortality rate is 99.1%. [1] It is thought that genetic factors and genetic heterogeneity are some of the causes underlying the aggressive behavior of pancreas cancer. [2] Various germline mutations associated with pancreas cancer were detected in the literature. The most significant genes increasing the pancreas cancer risk were reported as BRCA1, BRCA2, PALB2, ATM, CDKN2A, APC, MLH1, MSH2, MSH6, PMS2, PRSS1 and STK11. [3-5]
OTT_A_201373 5551..5561

Department of Gastroenterology, Fujian Medical University Union Hospital, Fuzhou, Fujian 350001, People’s Republic of China Background: 12-Lipoxygenase (12-LOX) plays a major role in the progression and metastasis of various types of cancer. In gastric cancer (GC), the expression level of 12-LOX is significantly up-regulated; however, its function, and underlying mechanism of action remain unclear. Methods: The mRNA and protein expression levels of 12-LOX were assessed using quantitative reverse transcription polymerase chain reaction (qRT-PCR) and Western blot analyses, respectively, in GC cell lines. 12-LOX expression was stably up-regulated using lentiviral vector in BGC823 and MGC803 cells, and cell-counting kit-8 (CCK8), colony formation, and invasion assays were performed to verify the function of 12-LOX in proliferation and metastasis. In addition, the expression levels of epithelial-mesenchymal transition (EMT) differentiation markers and downstream targets of the Wnt/β-catenin signaling pathway were examined by Western blotting. A nude mouse model of tumor growth and metastasis was established to investigate the role of 12-LOX in vivo. Results: Our findings demonstrate that 12-LOX mRNA and protein were highly expressed in GC cell lines. 12-LOX overexpression promoted GC cell proliferation, migration, and invasion both in vitro and in vivo. In addition, up-regulation of 12-LOX promoted the EMT in GC cells, as reflected by a decrease in E-cadherin expression and an increase in Ncadherin and Snail expression. 12-LOX overexpression in GC cells also increased the expression of multiple downstream targets of the Wnt/β-catenin signaling pathway. Conclusion: These findings revealed that 12-LOX functions as an oncogene in promoting GC cell proliferation and metastasis in vitro and in vivo. In addition, 12-LOX might regulate the EMT via the Wnt/β-catenin signaling pathway, indicating a potential role for 12-LOX as a target in GC treatment.
COMPUTATION TOOLS 2012 Proceedings

-In this paper, we examine a ready-to-use, robust, and computationally fast fixed-size memory pool manager with no-loops and no-memory overhead that is highly suited towards time-critical systems such as games. The algorithm achieves this by exploiting the unused memory slots for bookkeeping in combination with a trouble-free indexing scheme. We explain how it works in amalgamation with straightforward step-by-step examples. Furthermore, we compare just how much faster the memory pool manager is when compared with a system allocator (e.g., malloc) over a range of allocations and sizes. Keywords-memory pools; real-time; memory allocation; memory manager; memory de-allocation; dynamic memory
An Econometric Approach to Private Sector Credit in Lesotho

This reseach paper investigates the effect of various factors on the supply of credit to the private sector in Lesotho. It employs an autoregressive distributed lag cointegration approach using quarterly time series data for the period 2005 to 2014. There are numerous research papers that have examined the determinants of private sector credit, but they are primarily of a cross-country nature and are prone to distortionary concerns. The empirical results of this study for Lesotho, both short and long-run, indicate a significant positive relationship between the supply of credit to the private sector and bank deposits. In constrast, commercial bank net foreign assets and interest rates are significant and negative on the supply of credit; non-performing loans are insignificant in affecting credit to the private sector. Given the importance of private sector credit, it is recommended that there be expedited implementation of the Financial Sector Development Strategy’s objectives. The strategy of the Central Bank of Lesotho should be to build on previous policy initiatives to establish the necessary preconditions for expanding access to finance.
Application of Laser Doppler Anemometry to estimate turbulent power spectra inside an urban canopy

In the present contribution, we propose to make use of Laser Doppler Anemometry to investigate the dynamics of the flow inside an urban canopy immersed into a thick turbulent boundary layer. Previous studies dedicated to such flows (Castro et al. 2006; Reynolds and Castro 2008) have focused the core of their analysis on the roughness sublayer region or on the inertial region. In contrast, the region below the canopy interface have received little attention so far, and only mean velocity or Reynolds stresses data can be found in the literature. Indeed, getting access to the dynamics of the flow inside the canopy represents a real experimental challenge: the flow is turbulent, 3-dimensionnal, and due to the tight clearance, only non-intrusive laser-based techniques such as LDA or PIV can be used. In this contribution, for the first time, a spectral analysis of the flow is carried out inside the canopy region. This is made possible thanks to very thorough LDA measurements as well as the use of advanced post-processing algorithm to compute temporal power spectra. Indeed, LDA measurement yields non-equidistantly spaced data points, and standard FFT algorithms cannot be used. A detailed comparison of various algorithms is undertaken, and a slight improvement is proposed to reduce the impact of measurement noise. Finally, the power spectra inside the canopy are analyzed and the main implications on the flow dynamics are discussed.
On the Existence and Characterization of Binary Perfect Frequency Distance Codes

This paper deals with the study of Perfect Binary codes with Frequency distance. The study of Perfect codes is a classic problem in Algebraic Coding Theory.Perfect codes over finite fields with Hamming metric were studied extensively and a complete characterization was obtained for the class of these codes.The non-existence of Perfect codes in Rank metric also has been proved. In this work, the existence of Perfect Binary codes with Frequency distance is proved and a characterization of this class of codes is obtained.
Complications of arteriovenous fistula for haemodialysis access

Vascular access care is a classic example of multidisciplinary team work between nephrologists, vascular surgeons, interventional radiologists, ultrasound technicians and dialysis nurses. To achieve the best outcome the team must agree on a set of goals, collaborate closely and maintain good mutual communication. A key player in this multidisciplinary approach is a dedicated access coordinator who acts as a liaison officer between the disciplines and schedules the meetings. The assimilation of recommendations and guidelines into clinical practice is only possible if all parties involved are willing and motivated to cooperate. In 2003, the United States National Vascular Access Improvement Initiative (NVAII) launched Fistula First. This is a large national initiative that offers a set of tools ABSTRACT
Human Evolution, Genes and E-Communication in Organizations

Could our genes influence our behavior toward e-communication tools? This paper argues that they can and illustrates the mechanism underlying their influence. An alternative to the media richness hypothesis, proposed by media richness theory, is developed. This new hypothesis, called media naturalness hypothesis, states that there is a negative causal link between the degree of naturalness of an e-communication medium (or its similarity to the face-to-face medium) and the degree of cognitive effort required from an individual to use the medium in an e-communication interaction. The new hypothesis is based on an analysis of the evolution of the human biological communication apparatus through natural selection, according to the laws proposed by Darwin(cid:146)s theory of evolution by natural selection. Key implications for managers are discussed, particularly for the development of business-to-consumer e-communication tools.
DATA ANALYTICS 2013

—Online credit card fraud represents a significant challenge to online merchants. In 2011 alone, the total loss due to credit card fraud amounted to $ 7.60 billion with a clear upward trend. Especially online games merchants have difficulties applying standard fraud detection algorithms to achieve timely and accurate detection. The present paper introduces a novel approach for online fraud detection, called DNA. It is based on a formula which uses attributes that are derived from a sequence of transactions. The influence of these attributes on the result of the formula reveals additional information about this sequence. The result represents a fraud level indicator, serving as a classification threshold. A systematic approach for finding these attributes and the mode of operation of the algorithm is given in detail. The experimental evaluation against several standard algorithms on a real life data set demonstrates the superior fraud detection performance of the DNA approach (16.25 % better fraud detection accuracy, 99.59 % precision and low response time). In addition to that, several experiments were conducted in order to show the good scalability of the suggested algorithm.
Image Search Engine of Mono Image

— In recent year, images are widely used in many applications, such as facebook, snapchat. The large numbers of these images are saved in the smart system to easy access and retrieve. This paper aims to design and implement the new algorithm which is used in search of images. The mono image (black and white) is used as input data to the proposed algorithm. The methodology of this paper is to split image into number of block (block size = 8*8). For each block set 1 or 0 in order to count the number of black and white pixels. Finally, the result compare with other image dataset with the threshold value. The result show's that the proposed algorithm is successful passed in tested stage.
Updated Review on Surgical Management of Male Hypogonadism

In this review, we discuss the treatment options for male hypogonadism and the associated benefits and potential shortand long-term risks. The choice for treatment may depend on the cause of hypogonadism and the desire for maintaining or improving fertility. We also highlight surgical management of male hypogonadism. Comprehensive searching strategy through Well-known medical databases (MIDLINE/ PubMed, and Embase) searching articles that published in English language up to December 2017, and discussing the surgical management of male hypogonadism. Malehypogonadism is identified by the presence of symptoms or signs of male hypogonadism and consistent serum testosterone levels that are below the normally accepted adult male range. Once the medical diagnosis is confirmed, the primary goal of treatment is testosterone substitution to accomplish serum testosterone levels that remain in the mid-adult range and the symptoms and signs of hypogonadism are eliminated. Recent developments led to numerous delivery systems for testosterone. For patients with primary hypogonadism testosterone therapy is the approach of choice. The patient needs to be completely informed about expected benefits and side-effects of the treatment option. The option of the preparation should be a joint decision by a notified patient and the doctor.
AN ANALYTICAL APPROXIMATION FOR THE LOCAL FLOW BETWEEN COUNTER-ROTATING CYLINDER PAIR

Silindir cifti etrafindaki akis, pek cok uygulamayi ilgilendirir. Ozellikle kendini ittiren, otonom araclarin gelistirilmesiyle bu konu daha da onem kazanmistir. Bu akis ve onun silindirler uzerindeki etkileri uzerine deneysel, sayisal ve cok daha az olcekte teorik calismalar olmustur. Ne var ki problemin kompleksligi, genel bir cozume izin vermemekte ve her durum icin ayri cozum uretilmistir. Bu calismada, teorik bir yaklasim benimsenmis ve zit donen silindir cifti arasindaki lokal akis modellenmistir. Surekli, laminer, sikistirilamaz bir akis icin pratik formuller elde etmek icin Navier-Stokes denklemleri sadelestirilmis ve yeni, parabolik bir koordinat sisteminde ifade edilmistir. Daha sonra, problemin simetrik dogasindan dolayi daha baska basitlestirmeler uygulanmistir. Son olarak sinir kosullar tatbik edilmis, integraller alinmis ve hiz ve basinc icin arzulanan denklemlere ulasilmistir. Cok yavas akislarla kisitli olan onceki calismalarin aksine, bu calismada elde edilen denklemler butun sikistirilamaz, laminer akis rejimlerinde gecerlidir, yeter ki silindirlerin arasi soz konusu olsun. Bu denklemler kullanilarak, donme hizinin,silindirler arasi boslugun ve silindir yaricapinin etkileri calisilmis ve grafik olarak sunulmustur.
Alector: A Parallel Corpus of Simplified French Texts with Alignments of Misreadings by Poor and Dyslexic Readers

In this paper, we present a new parallel corpus addressed to researchers, teachers, and speech therapists interested in text simplification as a means of alleviating difficulties in children learning to read. The corpus is composed of excerpts drawn from 79 authentic literary (tales, stories) and scientific (documentary) texts commonly used in French schools for children aged between 7 to 9 years old. The excerpts were manually simplified at the lexical, morpho-syntactic, and discourse levels in order to propose a parallel corpus for reading tests and for the development of automatic text simplification tools. A sample of 21 poor-reading and dyslexic children with an average reading delay of 2.5 years read a portion of the corpus. The transcripts of readings errors were integrated into the corpus with the goal of identifying lexical difficulty in the target population. By means of statistical testing, we provide evidence that the manual simplifications significantly reduced reading errors, highlighting that the words targeted for simplification were not only well-chosen but also substituted with substantially easier alternatives. The entire corpus is available for consultation through a web interface and available on demand for research purposes.
Improved Access to Diagnostics for Rhodesian Sleeping Sickness around a Conservation Area in Malawi Results in Earlier Detection of Cases and Reduced Mortality

Trypanosoma brucei rhodesiense Human African Trypanosomiasis (rHAT) is a zoonotic disease transmitted by tsetse flies from wild and domestic animals. It presents as an acute disease and advances rapidly into a neurological form that can only be treated with melarsoprol, which is associated with a high fatality rate. Bringing diagnostic services for rHAT closer to at-risk populations would increase chances of detecting cases in early stages of disease when treatment is safer and more effective. In Malawi, most of the rHAT cases occur around Vwaza Marsh Wildlife Reserve. Until 2013, diagnosis of rHAT in the region was only available at the Rumphi District Hospital that is more than 60 km away from the reserve. In 2013, Malawi’s Ministry of Health initiated a project to enhance the detection of rHAT in five health facilities around Vwaza Marsh by upgrading laboratories and training technicians. We report here a retrospective study that was carried out to evaluate the impact of improving access to diagnostic services on the disease stage at diagnosis and on mortality. Between August 2014 and July 2017, 2014 patients suspected of having the disease were tested by microscopy, including 1267 who were tested in the new facilities. This resulted in the identification of 78 new rHAT cases, of which six died. Compared with previous years, data obtained during this period indicate that access to diagnostic services closer to where people at the greatest risk of infection live promotes identification of cases in earlier stages of infection, and improves treatment outcomes.
Return Synchronicity in the Bond Market

This paper studies the information interpretation of return synchronicity in the corporate bond market. The investment-grade bonds, bonds that ratings do not split, and the bonds issued by publicly listed firms are associated with higher levels of bond return synchronicity. We verify the event intensity rationale by using rating change announcement as a proxy for the specific event. Bond-years that ratings get changed exhibit lower return comovement. This negative relationship between rating changes and bond return synchronicity is more pronounced for rating downgrades relative to rating upgrades. All the results remain robust after controlling for bond characteristics, industry-fixed as well as year-fixed effects, and using the sample aggregated at the issuer level.
Gastrointestinal perforation peritonitis in India: A study of 442 cases

Introduction: Perforation is defined as an abnormal opening in a hollow organ or viscus. Gastrointestinal perforation is one of the common surgical emergencies in developing countries. The diagnosis is mainly clinical and is aided by radiological investigations. The present study was conducted to highlight the spectrum of hollow viscus perforation peritonitis in terms of etiology, clinical presentations, site of perforation, surgical treatment, postoperative complications, and mortality encountered at SMS Medical College and Hospital, Jaipur, India. Materials and Methods: The study was a hospital-based prospective observational study conducted from April 2012 to October 2013 in the Department of General Surgery. During the study period, a total of 442 patients underwent surgery for secondary peritonitis. The patients included in the study were patients (>12 years) presenting with gastrointestinal perforation and undergoing emergency laparotomy. Results: Out of 442 patients, 91.2% (403) were males, with male-to-female ratio being 10.33:1. The mean age was 39.13 years. About 79.2% of the patients were below 50 years. Free gas under diaphragm on chest X-ray was noted in 86.2% cases. Duodenum was the most common site of perforation in 158 patients. The most common etiology for perforation was acid peptic disease (41.4%). Simple closure was the most common surgical procedure being performed in 63.8%. Overall morbidity and mortality recorded in this study were 42.8% and 14.7%, respectively. Conclusion: Early diagnosis, resuscitation with fluids, and timely surgical intervention are the most important factors deciding the fate of the patient with perforation peritonitis.
ROLE OF SERUM PERIOSTIN AS A BIOMARKER IN DIAGNOSIS OF BRONCHIAL ASTHMA

Background Asthma is a chronic airway disease that is characterized by persistant airway inflammation and remoldeing with bronchial hyperactivity in resulted from one allergen or more leading to episodic airflow obstruction. Periostin can be detected in serum of asthmapatients which largly reflected to its level production in airway. Periostin is secreted by airway epithlialcellin response to iL-13 stimulation and easly leak into the airway capillary. Serum periostin could be aperdector ofairway esinophilliato patients with severeasthma. Aim of the work Is estimating the serum periostin level in patients with bronchial asthma to evaluate its role in diagnosis. Methodology This study was carried out on 25 normal healthy individual serveing as control (Group I), 25 patients diagnosed as atopic asthmatic patient regarding to skin prick test (its postive>3) (Group II) and 25 patients diagnosed as non-atopic asthmatic patient regarding to skin prick test (its negative <3) (Group III). Informed consent was taken from all patients and controls. Patient was submitted to full History taking, Clinical evaluation, Chest X-ray, Pulmonary function tests, Skin prick test to inhalant allergens and laboratory investigations including (CBC and Serum levels of periostin were assayed using an enzyme-linked immunosorbent assay (ELISA). Results Statistical analysis of the results of present work showed that serum periostin was significantly higher in asthmatic group (atopic and non atopic) in comparison to control group. Serum perioestin was also significantly higher in group 11 (atopic asthma) than group 111 (non atopic asthma) as cutting off was>420 and sensitivity and specifity was 40.0, 100.0 resepctivily. Conclusion Serum periostin can be used in dignosis of asthma and differntiation of atopic asthma from non atopic asthma.