Miracle-dz/UniFAR-FTUs huggingface dataset:
P retention and cation exchange as affected by nanoparticle of volcanic ash and application of phosphate solubilizing bacteria on Andisol Ciater, West Java, Indonesia

Andisols is a soil with high retention of phosphate and cannot be absorbed by plants. Some of soil bacteria have the ability to solubilize P and make it available to growing plants are known phosphate solubilizing bacteria (PSB). The research aims to study the effect of nanoparticle volcanic ash and phosphate solubilising bacteria (PSB) on P retention and cation exchangeable (CEC) in Andisol Ciater, West Java. This research was conducted from October 2016 to March 2017. The design of the analysis used was a complete randomized factorial design with two factors. The first factor was nanoparticle volcanic ash (a) consists of four dosages based on weight percentage (0%, 2.5%, 5.0% and 7.5%) and the second factor was PSB (h) consists of two dosages (without biofertilizer and with biofertilizer 1 g/Kg soil). The combination treatments replicated three times were incubated for 4 months. Soil samples were analyzed at first month and fourth month after incubation. The results showed that all dosages of nanoparticle volcanic ash and application of PSB decreased P retention by 75-77% at the first month after incubation. Nanoparticle volcanic ash dosage decreased to 7.5% the P retention reaches 90.36% in the fourth month after incubation. The nanoparticle of volcanic ash dosage 7.5% increased with CEC (24.787 cmol.kg−1 and 16.555 cmol.kg−1) at the first and fourth months after incubation. The application of PSB increased the CEC (28.606 cmol.kg−1) in the first month after incubation.Andisols is a soil with high retention of phosphate and cannot be absorbed by plants. Some of soil bacteria have the ability to solubilize P and make it available to growing plants are known phosphate solubilizing bacteria (PSB). The research aims to study the effect of nanoparticle volcanic ash and phosphate solubilising bacteria (PSB) on P retention and cation exchangeable (CEC) in Andisol Ciater, West Java. This research was conducted from October 2016 to March 2017. The design of the analysis used was a complete randomized factorial design with two factors. The first factor was nanoparticle volcanic ash (a) consists of four dosages based on weight percentage (0%, 2.5%, 5.0% and 7.5%) and the second factor was PSB (h) consists of two dosages (without biofertilizer and with biofertilizer 1 g/Kg soil). The combination treatments replicated three times were incubated for 4 months. Soil samples were analyzed at first month and fourth month after incubation. The results showed that all dosages of nanopartic.
Spatial-temporal variables for swimming coaches: A comparison study between video and TritonWear sensor

The main aim of this study was to evaluate the validity and the reliability of a swimming sensor to assess swimming performance and spatial-temporal variables. Six international male open-water swimmers completed a protocol which consisted of two training sets: a 6×100m individual medley and a continuous 800 m set in freestyle. Swimmers were equipped with a wearable sensor, the TritonWear to collect automatically spatial-temporal variables: speed, lap time, stroke count (SC), stroke length (SL), stroke rate (SR), and stroke index (SI). Video recordings were added as a “gold-standard” and used to assess the validity and the reliability of the TritonWear sensor. The results show that the sensor provides accurate results in comparison with video recording measurements. A very high accuracy was observed for lap time with a mean absolute percentage error (MAPE) under 5% for each stroke (2.2, 3.2, 3.4, 4.1% for butterfly, backstroke, breaststroke and freestyle respectively) but high error ranges indicate a dependence on swimming technique. Stroke count accuracy was higher for symmetric strokes than for alternate strokes (MAPE: 0, 2.4, 7.1 & 4.9% for butterfly, breaststroke, backstroke & freestyle respectively). The other variables (SL, SR & SI) derived from the SC and the lap time also show good accuracy in all strokes. The wearable sensor provides an accurate real time feedback of spatial-temporal variables in six international open-water swimmers during classical training sets (at low to moderate intensities), which could be a useful tool for coaches, allowing them to monitor training load with no effort.
The Influence of Covid-19 Lockdown on Body Mass Index, Depression, Anxiety and Stress among Medical Students

The Covid-19 pandemic has wreaked havoc throughout the world, with 150 million cases to date and over 3 million lives claimed worldwide. Objectives: To explore the impact of the Covid-19 lockdown on psychological health parameters i.e. depression, anxiety and stress as well as on body mass index among medical students studying in a private medical college in Pakistan. Study Design: Experimental study. Methodology: This study with enrolled students (n=233) was carried out after ethical review committee’s (ERC) approval at CMH Kharian Medical College (CKMC), Physiology Department, Kharian-Pakistan. Both male and female medical students were enrolled. In phase 1, the students reported to the Physiology laboratory where age and gender were recorded. The pre-lockdown readings of BMI and DASS-21(Depression, Anxiety, Stress) scale were taken. In phase-2, the post-lockdown readings of BMI and DASS-21 scale were taken once the students returned to campus. Statistical analysis: Data was analyzed by SPSS software, version 21. BMI and DASS-21 score were presented as mean + SD. Statistical significance was taken at p value <0.05. Results: In present study, results showed that there was a decrease in level of depression post-Covid-19-lockdown among enrolled subjects with significant p-values (0.019*) in the pre and post covid-19-lockdown comparison. Conclusion: We concluded that significant difference was seen between Pre & Post Covid-19-lockdown depression with p-value of <0.019. However, insignificant difference was seen between Pre & Post Covid-19-lockdown anxiety and stress with p-value of >0.05. Key Words: Covid-19 lockdown, Medical students, Depression, BMI and Anxiety.
Impact of Advertising Appeals on Children's Well-being: Exploring the Moderating Role of Disposition

This research study aimed to examine the effect of advertisement appeals on the psychological well-being of children and assess the moderating role of disposition in the relationship of children's psychological well-being and advertisement appeals. The study was conducted by using primary data. Data was collected through the survey conducted in three-time lags from the children of age ranging from 8 to 12 years. A self-administered questionnaire was distributed among a sample of 578 children. For the selection of sample nonprobability, convenience sampling technique was employed, whereas descriptive and inferential statistical tools were utilized for the data analysis with the help of statistical packages for social sciences (SPSS) and analysis of moment structure (AMOS) version 23. Research findings showed that advertising appeals have a significant positive effect on the psychological well-being of children. Furthermore, disposition positively moderates the relationship between advertising appeals and the psychological well-being of the children.
Use of ICTs by Tribal Farmers for Obtaining Agricultural Information in Southern Rajasthan

Most of the tribal farmers of Southern Rajasthan are using ICT tools for seeking the agricultural information via mobile phones, television, radio, kisan call centre, information kiosks, internet and expert system. The study was conducted in Southern Rajasthan covering two districts (Banswara and Dungarpur) on the basis of availability of maximum facilities and infrastructures to promote use of ICT. Empirical data were collected personally from 160 farmers through a structured interview schedule. The results showed that majority of the farmers owned mobile phones as well as television and radio. The most frequently used ICT for social communication, contacting middle men for the marketing of produce and contacting experts on real time basis was mobile phone followed by television. The use of radio and kisan call centre was lower as compared to mobile phones and TV due to ICT availability and access levels being lower than other ICTs. Internet, touch screen computer and information kiosk and other application were still being rarely used by young and educated. Majority of the farmers (60.62%) were used the ICTs during the evening hours due to free and leisure time and telecast or broadcast of agricultural programs during the evening hours.
Investigating the Use of Learning Management System (LMS) for Distance Education in Malaysia: A Mixed-Method Approach

Technology acceptance research explains the adaptation of learning technology by accounting for the use of technologies. This mixed-method study investigated the use of Learning Management Systems (LMS) for distance education in Malaysia using the extended Technology Acceptance Model (TAM). Limited studies on LMS for Malaysia higher education studies focusing on distance learning are warranted due to the diversity of resources, maturity, and education as working adults contrasting from traditional undergraduates. The survey on 205 respondents revealed that the extended TAM, which includes perceived resources, explained variance in attitudes (R2= 56.2%) and actual use (R2= 34.5%) adequately. Concurrently, indicating perceived ease of use and perceived resources as a determiner for the attitude which predicts actual use. Subsequently, a semi-structured interview on 15 respondents supported this as it was inferred that respondents’ attitude was mainly determined by their perception of the role of LMS to facilitate learning activities. Furthermore, inconveniences in accessing learning contents and lack of interactive learning activities are the respondents’ primary concern, reflecting on the predictive role of perceived ease of use. The findings also provide appropriate guidance for the pedagogical design and LMS implementation for distance education based on affordance and inclusivity.
Preclinical Drug Testing of the CDK 4/6 Inhibitor Palbociclib in Combination With a PI3K or MEK Inhibitor in Colorectal Cancer Cell Lines

Background: Studies have demonstrated the efficacy of Palbociclib (CDK 4/6 inhibitor), Gedatolisib (PI3K/mTOR dual inhibitor) and PD0325901 (MEK1/2 inhibitor) in colorectal cancer (CRC), however single agent therapeutics are often limited by resistance. The main purpose of this in vitro study is to comprehensively test two drug combinations [Palbociclib with Gedatolisib (P+G) and Palbociclib with PD0325901 (P+PD)] to determine the most synergistic combination for clinical development. Methods: We compared the anti-proliferative effects of both drug combinations in five CRC cell lines with various mutations (Caco-2, DLD-1, LS1034, SNUC4 and LS411N). Reverse Phase Protein Arrays was used to investigate the effects of P+G on the total and phosphoproteins of the signalling pathways. Results: Our results from toxicology experiments indicated that the P+G is a superior combination. The combination of P+G had synergistic anti-proliferative effects in all cell lines [CI range: 0.11-0.69]. The combination of P+PD is also synergistic in all cell lines [CI range: 0.06-0.44], except LS411N with BRAF V600E mutation [CI=14.7]. The combination of P+G caused significant suppression of S6rp(S240/244) in all cell lines, without AKT reactivation. This indicated efficient blockage of PI3K/AKT/mTOR pathway, even in PIK3CA mutated cell lines. The combination of P+G induced BAX and Bcl-2 levels in PIK3CA mutated cell lines. The combination of P+G caused MAPK/ERK reactivation, as seen in total EGFR increase and this was not mutationally exclusive. Conclusion : This in vitro study demonstrated that the combination of P+G has synergistic anti-proliferative effects in both wild-type and mutated CRC cell lines. This data provides good rationale for further in vivo studies for P+G novel combinative therapy in CRC. Separately, the S6rp(S240/244) may serve a promising biomarker of responsiveness.
Magnesium, Iron, Copper and Zinc in Vegetable Roots from Mato Grosso do Sul, Brazil

The inorganic components, especially magnesium, iron, copper and zinc contained in vegetable roots are of major importance, but seldom taken into account, either by general practitioners or by dietitians. The goal of this work is to report on magnesium, iron, copper and zinc in potatoes, sweet potatoes, cassava, yam and taro produced, and consumed in Campo Grande, the capital of Mato Grosso do Sul state, Brazil. After previous determination of humidity, the vegetables were digested with a mixture of HNO 3 and H 2 O 2 in the microwave digestion system Speedwave ® , Berghof, Germany. The levels of trace elements were measured using Inductively Coupled Plasma Optical Emission Spectrometry (ICP-OES, iCap 6000 ® - Thermo Scientific, USA). Most of the elements analyzed occur at levels within the range reported from international and Brazilian sources. However, iron in common potato, sweet potato and cassava was at the lowest level, while magnesium was very low in taro samples. The bioelements studied cannot pose any serious health risks and the edible tuberous roots widely consumed in Mato Grosso do Sul may represent an important source of essential micronutrients. The data show exclusively the population exposure to these minerals, no assumptions made as to their real absorption or bioavailability. DOI: http://dx.doi. org/10.17807/orbital.v9i3. 929
İş tatmini ile tükenmişlik ilişkisi: Bir meta-analiz çalışması

Bu çalışmanın amacı, Türkiye coğrafyasında faaliyet gösteren örgüt çalışanlarında tükenmişlik ve iş tatmini arasındaki ilişkinin incelendiği çalışmaların toplam etkisini meta-analiz yöntemiyle belirlemektir. Bu amaç doğrultusunda, Ocak 2010 ve Aralık 2019 tarihleri arasında tükenmişlik ile iş tatmini ve tükenmişlik ile iş doyumu konularını ele alan tez ve makalelerden elde edilen veriler kullanılmıştır. Meta-Analiz çalışmasına tükenmişlik ve iş tatmini (iş doyumu) ilişkisini araştıran ve korelasyon verilerini kullanarak etki büyüklüğünü hesaplamak için gereken korelasyon (Pearson) katsayısı ve örneklem sayısı bulunan 72 çalışma sonucu dahil edilmiştir. Çalışma analizleri CMA 3.0 programı aracılığıyla elde edilmiştir. Yayın yanlılığı, Huni Grafiği, Begg ve Mazumdar Testi ve Hata Koruma Sayısı N istatistiği ile incelenmiştir. Etki büyüklükleri korelasyon verilerini kullanarak hesaplanmış, sonuçlar Cohen d etki büyüklüklerine göre yorumlanmıştır. Rassal etki modeli analiz sonuçlarına göre tükenmişlik ve iş tatmini arasındaki ilişki orta düzeydedir (EB= -0,457, p <0,005). Araştırmaya dahil edilen çalışmaların örneklem çeşidi, çalışma bölgesi ve çalışma yıl aralığı değişkenlerinin tükenmişlik ve iş tatmini ilişkisinde moderatör rolü bulunmamaktadır.
Pós covid-19: as sequelas deixadas pelo Sars-Cov-2 e o impacto na vida das pessoas acometidas

Por meio da sua facilidade de transmissão e altas taxas de mortalidade, o SARS-CoV-2 até 2021 já infectou mais de 15 milhões de brasileiros. Além do período de incubação e manifestação dos sinais clínicos, a COVID-19 acarreta em muito mais sofrimento pela permanência de sequelas que retardam esse quadro, causando infecção multissistêmica pelo acometimento de tecidos vitais como o cardiológico, muscular, neurológico e psicológico. Sendo necessário o manejo por meio da reabilitação que tem por finalidade proporcionar a reversão e melhora funcional, física e emocional dos acometidos. O presente estudo teve por objetivo investigar as principais sequelas acarretadas pela COVID-19 nos pacientes em reabilitação, bem como a análise do impacto na qualidade de vida e bem-estar desses indivíduos. Com relação aos aspectos metodológicos, trata-se de uma revisão bibliográfica sistemática em que foram realizadas buscas na literatura e selecionados 26 estudos que atendiam os critérios de inclusão, por meio das bases de dados do Google Acadêmico, SciELO e PubMed publicados no período de 2020 a 2021, nos idiomas português e inglês. Mediante análise do material encontrado, as afecções referentes ao sistema pulmonar são as mais evidentes por representar o órgão alvo do vírus, comumente desencadeando sintomas como dispneia, fadiga e em quadros clínicos mais graves a fibrose pulmonar. O acometimento cardiovascular resulta em lesão cardíaca aguda, miocardite, inflamação vascular e arritmias cardíacas, enquanto que as disfunções olfativas e gustativas pertinentes ao sistema neurológico são amplamente relatadas. As sequelas musculoesqueléticas envolvem fraqueza ocasionada pela sarcopenia e perda de força muscular em resposta a infecção viral, imobilidade e nutrição insuficiente. O abalo psicológico e emocional surgem em decorrência do processo de isolamento social além do medo pelo potencial risco de morte, deteriorando a saúde mental desses indivíduos pela ansiedade, depressão e estresse pós-traumático. A reabilitação exige atuação de uma equipe multidisciplinar por medidas fisioterapêuticas que possibilitem a reintegração social do indivíduo e considerável melhora em sua qualidade de vida de forma independente. Portanto, é nítida a necessidade da continua produção cientifica de múltiplas perspectivas sobre temáticas referentes à COVID-19, sobretudo pela sua constante evolução.
HOTS AND E-LEARNING OF DIPLOMA AND UNDERGRADUATE: ILMIZI MODEL FOR ENVIRONMENTAL DISASTER MITIGATION EDUCATION DURING NEW NORMAL COVID-19

Innovation in learning is a necessity for environmental learning in 21st century especially during the new normal era of the Coronavirus Disease 2019 (COVID-19). One of important skills to address disaster mitigation issue is Higher Order Thinking Skills (HOTS) that can be trained using the Innovation Learning Model for Natural Science and Environmental Learning (ILMIZI) model regarding e-learning. This research aims to measure HOTS and descriptively analyse the e-learning and ILMIZI model. The research method is descriptive with survey as the data collection technique. The total sample size of this research were 176 students divided into 105 diploma students and 71 undergraduate students. The results show a very low HOTS score of students at the diploma (30.98) and undergraduate (32.02) level regarding disaster mitigation concepts. This study also considered the dominant use of Power Point file (41.38%), distractions in e-learning related to phone signals (44.83%), and the study discovered that majority of students feel more independent in learning (62.07%). The descriptive analysis indicates that the ILMIZI model is compatible for use in environmental learning concerning disaster mitigation. It is the finding of this research that student’s HOTS scores are still low;the implementation of e-learning programmes faces some obstacles;and the ILMIZI model is suitable for environmental learning as a means of disaster mitigation. © 2021, Journal of Sustainability Science and Management. All Rights Reserved.
Effects of Emotions and Ethics on Pro-Environmental Behavior of University Employees: A Model Based on the Theory of Planned Behavior

Over the last few years, many activities conducted by university employees have contributed greatly to the global rise of greenhouse gases responsible for the warming of the planet. This phenomenon can be attributed primarily to altering lifestyle, consumption, and portability patterns. Even though there is a significant applicability, understanding the factors determining the pro-environmental behavior (PEB) of university employees is lacking. Thus, this study extended the theory of planned behavior (TPB) to explain PEB among university employees. Ten hypotheses were suggested regarding the relations between the initial TPB constructs, environmental ethics, and emotional intelligence. A self-reported questionnaire was used to collect data from a randomly selected sample of 302 university employees from six Malaysian higher educational institutions listed in the UI Green Matrix 2016. The findings revealed that environmental ethics significantly affected attitudes, perceived behavioral control, and subjective norms. Furthermore, pro-environmental behavioral intentions (PEIs) were directly influenced by attitude and perceived behavioral control, while emotional intelligence mediated the relationship between PEIs and PEB. Moving forward, this study will provide new insights into the literature of university employees’ PEB using an expanded TPB model.
Hyperforin blocks neutrophil activation of MMP-9, motility and recruitment,and restrains inflammation-triggered angiogenesis and lung fibrosis

Hyperforin (Hyp), a polyphenol-derivative of St. John’s Wort, has emerged as key player in the anti-depressant activity of the plant, but also as inhibitor of bacteria lymphocyte and tumor-cell proliferation, and matrix proteinases. We tested whether as well as inhibiting leukocyte elastase (LE) activity, Hyp might be effective in containing both polymorphonuclear (PMN) leukocyte recruitment and unfavorable eventual tissue responses. The results show that, without affecting in vitro human PMN viability and chemokine-receptor expression, Hyp (as stable dicyclohexylammonium salt) was able to inhibit in a dose-dependent manner their chemotaxis and chemoinvasion (IC 50 1 µ M, for both); this effect was associated with a reduced expression of the adhesion molecule CD11b by fMLF-stimulated neutrophils, and block of leukocyte elastase (LE)-triggered activation of the gelatinase MMP-9. PMN-triggered angiogenesis is also blocked by both local injection and daily i.p . administration of the Hyp salt in an IL-8-induced murine model. Furthermore, i.p . treatment with Hyp reduces acute PMN recruitment, and enhances resolution in a pulmonary bleomycin-induced inflammation model, significantly reducing consequent fibrosis. These results indicate that Hyp is a powerful anti-inflammatory compound with therapeutic potential, and shed light on mechanistic keys. or 3 µ M), and fMLF plus Hyp-DCHA. Cells were centrifuged and incubated 30 min at 22 °C with the appropriate Ab, pelleted and resuspended in PBS. The expression of chemokine receptors or integrins was determined using monoclonal antibodies against CXCR1, CXCR2, CXCR3, CXCR4, CXCR6, CCR1, CCR2, CCR3, CCR5, CCR6, CCR7, CD62L, CD11a, CD11b, CD18. The effect of Hyp-DCHA was determined by overlaying the flow cytometry histograms of the untreated, fMLF-treated, and fMLF-plus-Hyp-DCHA-treated samples. Cells were scored using a FACSCalibur analyzer (Becton Dickinson), and data processed using Macintosh CELLQuest software program (Becton Dickinson). For each
Potential of Carica papaya Seed-Derived Bio-Coagulant to Remove Turbidity from Polluted Water Assessed through Experimental and Modeling-Based Study

It is important to develop renewable bio-coagulants to treat turbid water and efficient use of these bio-coagulants requires process optimization to achieve robustness. This study was conducted to optimize the coagulation process using bio-coagulant of deshelled Carica papaya seeds by employing response surface methodology (RSM). This bio-coagulant was extracted by a chemical-free solvent. The experiments were conducted using the Central Composite Design (CCD). Initially, the functional groups and protein content of the bio-coagulant were analyzed. The Fourier Transform Infrared Spectroscopy analysis showed that the bio-coagulant contained OH, C=O and C-O functional groups, which enabled the protein to become polyelectrolyte. The highest efficiency of the bio-coagulant was obtained at dosage of 196 mg/L, pH 4.0 and initial turbidity of 500 NTU. At the optimum conditions, the bio-coagulant achieved 88% turbidity removal with a corresponding 83% coagulation activity. These findings suggested that the deshelled Carica papaya seeds have potential as a promising bio-coagulant in treating the polluted water.