Miracle-dz/UniFAR-FTUs huggingface dataset:
Genomic and phenotypic characterization of Multisystem Inflammatory Syndrome in Children (MIS-C): a prospective multicenter study from the Middle East

Importance: Clinical, genetic and laboratory characteristics of patients with multisystem inflammatory syndrome in children (MISC) in the Middle East have not yet been documented. Objective: To uncover rare genetic variants contributing to MISC in patients of primarily Arab and Asian origin. Design, Setting, and Participants: A prospective multicenter cohort study was conducted between September 2020 and August 2021 in the United Arab Emirates and Jordan. Forty-five patients meeting the case definition of MISC, and a matched control group of twenty-five healthy children with a confirmed severe acute respiratory syndrome coronavirus 2 (SARSCoV2) infection status, were recruited. Whole Exome Sequencing (WES) in all 70 participants was performed to identify rare likely deleterious variants in patients with MISC and to correlate genetic findings with the clinical course of illness. Exposures: SARSCoV2. Main Outcomes and Measures: Fever, organ system complications, laboratory biomarkers, WES findings, treatments, and clinical outcomes. Mann Whitney U test was used to assess the association between genetic variations and MISC attributes. Fishers exact test was used to compute the genetic burden in MISC relative to controls. Results: In 45 MISC patients (23 boys [51.1%]; average age, 7 years [range, 2-14 years]), key inflammatory markers were significantly dysregulated in all patients. Mucocutaneous and gastrointestinal manifestations were reported in 80% (95% CI 66% to 89%) while cardiac and neurological findings were reported in 49% (95% CI 35% to 63%) and 31% (95% CI 19.5% to 45.6%) of patients, respectively. Rare, likely deleterious heterozygous variants in immune related genes including TLR3, TLR6, IFNAR2, IL22RA2, IFNB1, and IFNA6, were identified in 19 patients (42.2%, 95% CI 29% to 56.7%), of whom seven had more than one variant. There was significant enrichment of genetic variants in patients relative to the control group (29 versus 3, P<.0001). Those variants were significantly associated with earlier onset of disease (31.5%, 95% CI 15.4% to 54% of patients with versus 7.7%, 95% CI 2% to 24% without genetic findings were < 3 years) and resistance to treatment (42%, 95% CI 23% to 64% of patients with versus 11.5%, 95% CI 4% to 29% of patients without genetic findings received two doses of IVIG). Conclusions and Relevance: Rare, likely deleterious genetic variants contribute to MISC onset and management.
Continuum Modeling of an Innovative Space-Based Radar Antenna Truss

Many proposed inflatable designs for space applications consist of truss-like or lattice structures due to their simplicity of construction coupled with large stiffness to density ratios. An analytical approach is presented here in order to derive the governing partial differential equations of motion which are decoupled for bending and rotational coordinates of vibrations and applies this formulation to the truss structure model of an innovative space-based radar antenna. Kinetic and potential energy expressions are written in terms of nodal velocities and strain components of bar members within a repeating truss element. Hamilton’s principle is then employed to find the equations of motion for the system. The equations for bending are presented in their decoupled form in order to derive an equivalent Timoshenko beam model for the truss. Finally, the physical characteristics of the continuum model are written in terms of the material and geometrical properties of the original truss, which provide a simpl.
Towards Multi-Model Big Data Road Traffic Forecast at Different Time Aggregations and Forecast Horizons

Due to its usefulness in various social contexts, from Intelligent Transportation Systems (ITSs) to the reduction of urban pollution, road traffic prediction represents an active research area in the scientific community, with strong potential impact on citizens’ well-being. Already considered a non-trivial problem, in many real applications an additional level of complexity is given by the large amount of data requiring Big Data domain technologies. In this paper, we present the first steps of a novel approach integrating both classic and machine learning models in the Spark-based big data architecture of the H2020 CLASS project, and we perform preliminary tests to see how usually little-considered variables (different data aggregation levels, time horizons and traffic density levels) influence the error of the different models.
Pan evaporation and sensor based approaches of irrigation scheduling for crop water requirement, growth and yield of okra

Nowadays, the sector that consumes the major amount of fresh water in India is agriculture, and due to the limitation and scarcity of fresh water resources, it is necessary to manage irrigation rationally and emphasize on the selection of most appropriate method of irrigation scheduling for irrigating the crops under drip irrigation, so they can work more efficiently, minimizing waste in irrigated agriculture (Farias et al. 2017). Irrigation scheduling remains a very effective technique for applying the required amount of irrigation water at the appropriate time (Munoz-Carpena et al. 2005). The variation in water use efficiency is also resulted from variation in crop yield (Pradhan et al. 2018). An automated irrigation system is integrated with various types of electronic controllers and uses microclimate data to schedule water irrigation in order to save irrigation water and reduce non-pointsource pollution (Nautiyal et al. 2010). The okra (Abelmoschus esculentus L.) is a famous vegetable with more nutritional value, great acceptance in the market and belongs to the Malvaceae family. It is mainly cultivated mainly in tropical regions. The fertigation schedule was significantly influenced the vegetative growth, yield attribute, and quality characters parameters of okra crop (Jamrey et al. 2018). The current trend in such advanced irrigation techniques for conserving water and energy consumed for irrigation in agriculture is to switch from a manual system to automatic operations in a drip irrigation system with appropriate approach of irrigation and fertigation scheduling. The performance of soil moisture sensor based automated irrigation system has been tested for okra crop which shows good correlation between soil moisture by measured by sensor and soil moisture content by gravemetric method (Sharma et al. 2019). A judicious assessment of the water requirement of the crops is crucial for irrigation scheduling and planning of farm irrigation systems (Mushtaq et al. 2020). In view of above discussion, effort was made to assess the impact of various approaches of irrigation scheduling along with fertigation scheduling on growth, crop yield of okra and ABSTRACT
Control System Design over Unreliable Channels (cid:63)

This paper studies LTI control systems comprising a scalar unreliable channel in the feedback path. We show that, when such a channel drops data according to a Bernoulli process, it becomes equivalent, as far as second order moments are concerned, to an additive white noise channel with an instantaneous signal-to-noise ratio constraint. This equivalence allows one to characterize the set of all LTI controllers that achieve mean square stability in a general control architecture closed over a scalar unreliable channel, and also enables one to optimally design LTI controllers using standard tools. To illustrate our results, we study the (LTI dynamic output feedback) control of SISO plants subject to data dropouts. For this situation, we establish closed form necessary and suﬃcient conditions on the minimal successful transmission probability that allows one to design LTI controllers that achieve MSS, when either TCP or UDP-like communication protocols are employed.
Relative Effectiveness of Cell-Cultured versus Egg-Based Seasonal Influenza Vaccines in Preventing Influenza-Related Outcomes in Subjects 18 Years Old or Older: A Systematic Review and Meta-Analysis

Avian mutations in vaccine strains obtained from embryonated eggs could impair vaccine effectiveness. We performed a systematic review and meta-analysis of the adjusted relative vaccine effectiveness (arVE) of seed cell-cultured influenza vaccines (ccIV) compared to egg-based influenza vaccines (eIV) in preventing laboratory-confirmed influenza related outcomes (IRO) or IRO by clinical codes, in subjects 18 and over. We completed the literature search in January 2021; applied exclusion criteria, evaluated risk of bias of the evidence, and performed heterogeneity, publication bias, qualitative, quantitative and sensitivity analyses. All estimates were computed using a random approach. International Prospective Register of Systematic Reviews, CRD42021228290. We identified 12 publications that reported 26 adjusted arVE results. Five publications reported 13 laboratory confirmed arVE and seven reported 13 code-ascertained arVE. Nine publications with 22 results were at low risk of bias. Heterogeneity was explained by season. We found a significant 11% (8 to 14%) adjusted arVE favoring ccIV in preventing any IRO in the 2017–2018 influenza season. The arVE was 3% (−2% to 7%) in the 2018–2019 influenza season. We found moderate evidence of a significant advantage of the ccIV in preventing IRO, compared to eIV, in a well-matched A(H3N2) predominant season.
THE EFFECT OF OBESITY AND FLEXIBILITY TOWARD WOMEN’S BODY FAT IN PRODUCTIVE AGE AT LARASATI

Body Fat, Flexibility, Obesity Abstract _____________________________________________________ Obesity is an body fat increase. Overweight is a relative body weight increase when compared to the standard. Overweight then became a term that represented "obesity" both clinically and epidemiologically. Flexibility is the effectiveness of a person in adjusting himself to all activities with stretching the body in a wide area of the joint. The design used in this study is a 2x2 factorial. It is explained about factorial experiments that what is measured is not only the influence of the main factor of each independent variable on the dependent variable, but also the influence of the interaction between the independent variables. The population in this study is the 50 members of Larasati gymnastics in Semarang, who in productive age women between 30-40 years.The number of samples is quite representative (representing) for the large population in this study. The sampling technique in this study was using purposive sampling, which is a sampling technique determined by giving equal opportunity to each member of the population as a sample, namely the number is adjusted to the member of the subject in each group, the experimental group of obesity type pear and apple type obesity control group. Based on the results of the research achieved, it turns out that women who have high flexibility have a large reduction in fat if they have the apple type of obesity. Women who have high flexibility with apple obesity type have a better decrease in body fat than women with low flexibility and have pear obesity type. Fcount = 6.962> Ftable = 3.11. The effectiveness that is applied to reduce body fat is influenced by the type of high flexibility and type of low flexibility of those women.
User-Experience based Evaluation of the Jaxber App Towards competitive advantage through a study of User Experience

Technology has revolutionised the way that companies are run, and the competition between enterprises is fierce as breakthrough developments occur daily in the IT industry. Hence the sustainable development of competitive advantage is a priority for any enterprise wishing to survive, let alone excel on the market. User-Experience (UX) is one of the possible contemporary approaches aiming at achieving a competitive advantage. There are different models proposed for UX evaluation to address the user's needs efficiently. The objective of the study was to evaluate the user experience of the Jaxber mobile app as a potential source of competitive advantage and to find out which of the selected properties have changed over the years 2017 – 2018 and to inform the future development of the Jaxber app. A Holistic Model for UX evaluation was used as a theoretical framework in this study. A repeated cross-sectional mixed-methods study was implemented based on qualitative and quantitative secondary data provided by the organisation. ANOVA analysis and the Nonparametric Kruskal-Wallis Test were used for quantitative data analysis, and sentiment analysis and the cloud of terms were applied to qualitative data. The triangulation of results revealed that quantitative and qualitative results are complementary to each other. There was a statistical change for three (usefulness, novelty, and productiveness) of the seven selected properties. Sentiment analysis showed that the general opinion of the users of the Jaxber app is positive. Recommendations for improvement of the Jaxber app that came from the end-users of the mobile solution, when prioritized and implemented, may become a source of possible competitive advantages in the future. Keywords/tags (subjects) User Experience Jaxber, Mixed-Methods, Repeated Cross-Sectional study, Competitive Advantage Miscellaneous (Confidential information)
WAVELET-BASED SHIFT-INVARIANT NOISE MODEL WAVELET-BASED SHIFT-INVARIANT NOISE MODEL

This paper proposes the use of shift-invariant dual-tree discrete wavelet transform (DT DWT) noise model to the problem of a multipath signal detection in underwater environment. The design procedure for this adaptive model of the background noise is described. When an input signal is shifted, as in a multipath environment, this shift-invariant DT DWT can generate multi-resolution subspaces. Each of them keeps more coefficient energy of this signal than DWT’s. The result of computer simulations shows that this method can improve the performance of a multipath signal detection, by reducing the false alarm probability in a range of different signal-to-noise (SNR) ratios.
Impact of Functional and Schematic Overview Displays on Console Operators’ Situation Awareness

Console operators in process plants have to maintain a high level of situation awareness to operate the plant safely, effectively, and efficiently. An overview display is one of the primary displays in a control room that operators monitor to gain and maintain an understanding of the plant. In this study, the authors evaluated operator performance using two overview display formats. The first format, characterized as a functional design, included qualitative, graphical indicators for process parameters and organized the position of the indicators on the basis of functional relations of the process equipment. The second format, characterized as a traditional schematic display, showed connecting process lines between equipment and numerical fields to present process information. Both displays contained the same indicator values. Eighteen plant operators used both display formats to monitor a crude unit process for process parameters that deviated from normal values. We measured operators’ situation awareness using think-aloud protocols and situation awareness global assessment technique, subjective workload, and usability ratings. Results indicated that operators’ situation awareness was significantly higher when they monitored the process on a functional display compared with a schematic display. Their subjective workload and usability ratings also favored the functional overview display format. Implications of the findings for continuous process control and overview display design are discussed.
Contact resistance characteristics of Ag material in breaking low-load DC arcs

Contact resistance of Ag contacts was determined from nonload to 4 A under switching inductive load conditions. The tested results show that three characteristic contact resistance variations corresponding to three types of contact morphologies exist, and there are a critical transition load current and a critical transition operation cycle. When the load current is less than 0.2 A, which is called critical transition current, the contact resistance at the beginning of the operation, which is less than critical transition operation cycle, is like that in nonload condition, i.e., low and stable. If the load current is larger than this critical value, the contact resistance is, however, high and unstable during the whole test process. It is demonstrated that this phenomenon is attributable to arc occurrence probability and arc duration. Both mechanical factors (wear and mechanochemical reaction) and electrical factors (arc erosion and heat corrosion) are considered to be dominant in different load currents and different operation periods. >
Longitudinal Chinese Population Structural Fetal Brain Atlases Construction: toward precise fetal brain segmentation

In magnetic resonance imaging (MRI) studies of fetal brain development, structural brain atlases usually serve as essential references for the fetal population. Individual images are spatially normalized into a common or standard atlas space to extract regional information on volumetric or morphological brain variations. However, the existing fetal brain atlases are mostly based on MR images obtained from Caucasian populations and thus are not ideal for the characterization of the brains of the Chinese population due to neuroanatomical differences related to genetic factors. In this paper, we use an unbiased template construction algorithm to create a set of age-specific Chinese fetal atlases between 21-35 weeks of gestation from 115 normally developing fetal brains. Based on the 4D spatiotemporal atlas, the morphologically developmental patterns, e.g., cortical thickness, sulcal and gyral patterns, were quantified from in utero MRI. Additionally, after applying the Chinese fetal atlases and Caucasian fetal atlases to an independent Chinese pediatric dataset, we find that the Chinese fetal atlases result in significantly higher accuracy than the Caucasian fetal atlases in guiding brain tissue segmentation. These results suggest that the Chinese fetal brain atlases are necessary for quantitative analysis of the typical and atypical development of the Chinese fetal population in the future.
The Relation between Recurrent Aphthous Ulcers and Effort among Students in the Faculty of Dentistry at AL- Anbar University

Recurrent aphthous ulcer is a chronic disease among many people attending health centers and outpatient clinics seeking treatment. The current study aims to determine the repeated or chronic aphthous ulcers in students in the Faculty of Dentistry at Anbar University in Iraq and to determine the factors related to this ulcer. A cross-sectional study was conducted on 378 students at the College of Dentistry. The subjects included 229 females and 149 males. The ratio of female to male was 151. The obtained results showed that recurrent aphthous ulcer among the selected 378 dental students was 122(32.27%). in our study reported the prevalence of recurrent aphthous ulcer among female more than male 78(20.63%), 44(11.64%) respectively. According to the classes the prevalence of recurrent aphthous ulcer was more in the first and fifth stages 32(8.64%), 38(10.05%) respectively. The steps should be taken among medical students that not only mitigate their misery but also boost their academic performance.
PROXIMATE AND MINERAL COMPOSITION AND SOME ANTI-NUTRITIONAL FACTORS OF FLOUR FROM FIVE IMPROVED SWEET POTATO (IPOMOEA BATATAS (L.) LAM) VARIETIES ROOTS

Proximate and mineral compostion and some anti-nutritional factors of flour from roots of five (5) improved sweet potato (Ipomoea batatas L.Lam) varieties were determined. The parameters such as moisture, ash, crude protein, fat, fiber, total carbohydrate, total sugars and reducting sugars had contents in flours varying from 4.00 ± 0.20% dw to 5.19 ± 0.19% dw (dry weight), 3.25 ± 0.01% dw to 4.60 ± 0.40% dw, 1.61 ± 0.03% dw to 2.16 ± 0.01% dw, 0.60 ± 0.05% dw to 0.76 ± 0.10% dw, 1.25 ± 0.25% dw to 1.41± 0.14% dw, 87.70 ± 1.5% dw to 88.00 ± 0.60% dw, 1.43 ± 0.01% dw to 2.08 ± 0.01% dw, 0.11± 0.01% dw to 0.65 ± 0.01% dw respectively. Indeed, the rates ash, crude protein, Fat, Fiber, total carbohydrate, reducting sugar, Ca, Na, Mg, P and K in Kabode variety flour were found to be higher than those recorded in other varireties flours. Besides, the Analysis of Variance (ANOVA) showed that variety factor had significant effect (P≤ 0.05) on these parameters. It so appeared significant differences (p≤ 0.05) between their contents. Concerning caloric enregy, the values ranging from 374.8 ± 0.5Kcal/100g to 379.5 ± 0.1Kcal/100 g, didn‟t differ significantly (p˃0.05) from one variety to another. Furthermore, mineral elements (K, P, Mg, Ca and Na) studies were influenced by variety main effect and they varied significantly (p≤0.05). These minerals content found to be high in Kabode variety flour. Kabode, Irène, Fatoni and Bela Bela were the best sources of mineral elements and could be used in the diets of infants and young children. Otherwise, the results revealed that both kabode and Irène varieties flours contained high rate of oxalate (66.00 ± 0.01%) where as the phytate (9.46 ± 0.30%) and tannin (20.66 ± 0.20%) contents were found to be high in Tib variety flour. Besides, the Analysis of Variance (ANOVA) showed that the variety main effect had significant effects (P≤ 0.05) on these parameters. Thus, there were significant differences (P≤ 0.05) between their rates.
Shear strengthening of RC beams with FRP composites

Shear strengthening is required when an RC beam is found deficient in shear, or when its shear capacity falls below its flexural capacity after flexural strengthening. A recent technique for the shear strengthening of RC beams is to provide additional FRP web reinforcement, commonly in the form of bonded external FRP strips/sheets. Over the last few years, a large amount of research has been conducted on this new strengthening technique, which has established its effectiveness and has led to a good understanding of the behaviuor and strength of such shear-strengthened beams. This paper presents a state-of-the-art review of existing research on this topic. The methods of strengthening are described first, followed by a summary of experimental observations of failure processes and modes. The accuracy of existing design provisions is examined next through comparisons with test results. Limitations of existing experimental and theoretical studies are also highlighted. While the paper is mainly concerned with externally bonded FRP for shear strengthening, the emergence of alternative FRP shear strengthening techniques, including near-surface-mounted FRP and prestressed CFRP straps, is also noted.
Toward Understanding of Product Innovation Process in Construction

The peculiar characteristics of the products and the technological constraints of construction significantly differentiate it from manufacturing; this suggests that the process of innovation and the factors governing this process will differ. Based on an investigation of several product innovations in construction, this paper describes the characteristics of four key actors that play important roles in the innovation process in construction and the relationships among them. These actors are owner's demands, problems, designer's bank of technology, and contractor's process technology. This effort is the first step toward deciphering the mechanism of product innovation in construction, which has been neglected by researchers despite its immense importance to technological advancement in this vital industry. The paper also develops practical applications to assist industry professionals attempting to increase the rate of product innovation and implications to structure future research.