Miracle-dz/UniFAR-FTUs huggingface dataset:
Resilience-aware Optimal Design and Energy Management Scheme of Multi-energy Microgrids

In view of the recurrent power outages caused by various crises in recent years, such as high-impact natural catastrophes, the power and energy supply needs to be more resilient as well as affordable. The goal of this study is to present a grid-tied microgrid that will deliver continuous energy for both electrical and heating load demand at the lowest possible cost. The mixed-integer linear programming (MILP) based model optimizes multiple energy sources-PV, battery and combined heat and power (CHP) unit and runs during an extended blackout condition at different times of the year. Multiple simulation results show the model’s efficacy and resiliency in sustaining a continuous energy supply in the presence of power cuts, which also provides significant financial savings.
DELAYED VERSUS ACCELERATED WEIGHT-BEARING REHABILITATION PROTOCOL FOLLOWING ANTERIOR CRUCIATE LIGAMENT RECONSTRUCTION: A SYSTEMATIC REVIEW AND META-ANALYSIS

Objective To compare accelerated and delayed weight-bearing rehabilitation of anterior cruciate ligament reconstruction regarding clinical outcome measures of knee function (International Knee Documentation Committee Subjective Knee Form (IKDC), Lysholm Knee Scoring Scale, Tegner Activity Scale, and Knee Injury and Osteoarthritis Outcome Score (KOOS)), knee laxity, range of movement, quadriceps, and bone tunnel enlargement. Design Systematic review and meta-analysis. Methods Systematic searches of Embase, MEDLINE, CINAHL, and the Cochrane Library databases, from inception to February 2021, for studies comparing delayed or accelerated weight-bearing rehabilitation protocol after anterior cruciate ligament reconstruction in adult patients. Results Nine studies met the eligibility criteria. A meta-analysis revealed a higher risk of knee laxity in the accelerated weight-bearing group. Accelerated weight-bearing may be related to higher IKDC scores, while there was no statistical difference for Lysholm, Tegner, and KOOS scores at a follow-up within 2 years. Four of 5 studies reported no statistical difference for quadriceps strength and range of movement scores, while 2 studies reported bone tunnel enlargement in the accelerated weight-bearing group. Conclusion This systematic review confirmed that accelerated weight-bearing caused more serious knee laxity and bone tunnel widening than delayed weight-bearing after anterior cruciate ligament reconstruction. We therefore recommend that clinicians should select postoperative rehabilitation programmes with caution. LAY ABSTRACT Anterior cruciate ligament rupture is one of the most common sports injuries. This systematic review confirmed that accelerated weight-bearing rehabilitation resulted in more serious knee laxity and bone tunnel widening than delayed weight-bearing rehabilitation after ACLR. We therefore recommend that clinicians should select postoperative rehabilitation programmes with caution.
Usability Inspection of a Mobile Cancer Telerehabilitation System

Cancer rehabilitation (CR) has been shown to address physical impairments and progressive disablement experienced by patients with cancer. Access to CR is limited by multiple barriers. Previous studies demonstrated that telemedicine approaches may facilitate access to rehabilitation services however usability and acceptance of cancer telerehabilitation has not been systematically evaluated. This goal of this study was usability inspection of a mobile cancer telerehabilitation system based on cognitive walkthroughs and heuristics evaluations, supplemented by surveys to capture health literacy, patient engagement, and acceptance. The System Usability Scale provided a standardized reference for usability and satisfaction, and the mean result of 83.2±16.9 placed this mobile interface in the top 10th percentile. A semi-structured qualitative interview provided actionable feedback, which informed the next iteration of this project. Overall, this mobile telerehabilitation system was considered by cancer patients easy-to-use, satisfying, and engaging with 91% of participants planning to use it in the future.
Comparison of FDG PET/CT and Bone Marrow Biopsy Results in Patients with Diffuse Large B Cell Lymphoma with Subgroup Analysis of PET Radiomics

Whether FDG PET/CT can replace bone marrow biopsy (BMBx) is undecided in patients with diffuse large B cell lymphoma (DLBCL). We compared the visual PET findings and PET radiomic features, with BMBx results. A total of 328 patients were included; 269 (82%) were PET-negative and 59 (18%) were PET-positive for bone lesions on visual assessment. A fair degree of agreement was present between PET and BMBx findings (ĸ = 0.362, p < 0.001). Bone involvement on PET/CT lead to stage IV in 12 patients, despite no other evidence of extranodal lesion. Of 35 discordant PET-positive and BMBx-negative cases, 22 (63%) had discrete bone uptake on PET/CT. A total of 144 patients were eligible for radiomic analysis, and two grey-level zone-length matrix derived parameters obtained from the iliac crests showed a trend for higher values in the BMBx-positive group compared to the BMBx-negative group (mean 436.6 ± 449.0 versus 227.2 ± 137.8, unadjusted p = 0.037 for high grey-level zone emphasis; mean 308.8 ± 394.4 versus 135.7 ± 97.2, unadjusted p = 0.048 for short-zone high grey-level emphasis), but statistical significance was not found after multiple comparison correction. Visual FDG PET/CT assessment and BMBx results were discordant in 17% of patients with newly diagnosed DLBCL, and the two tests are complementary in the evaluation of bone involvement.
Guidance on the application of cable median barrier: Tradeoffs between crash frequency, crash severity, and agency costs

Median-crossover crashes present the highest risk of fatality and severe injury among collision types on freeways. These crashes can be caused by a variety of factors, including drowsiness, driver distraction, impaired driving, and loss of control. The primary countermeasure to reduce the opportunity for such crashes is the installation of median barriers. The Michigan Department of Transportation (MDOT) began installing hightension cable median barriers in 2008, and has installed approximately 317 miles of cable median barrier on state freeways as of January 2014. Given the capital costs required for this installation program, a comprehensive before-after evaluation was conducted in order to ascertain the efficacy of cable barrier systems installed to date, and to develop guidelines to identify candidate locations for subsequent installations. Crash reports were reviewed to identify target median-related crashes and this manual review provided critical supplementary information not normally available from the standard fields on police crash report forms. Statistical analyses which accounted for regression-tothe-mean effects showed that fatal and incapacitating injury crashes were reduced by 33 percent after cable barrier installation. The analysis also showed the median cross-over crash rate was reduced by 86.8 percent and the rate of rollover crashes was reduced by 50.4 percent. In contrast, less severe crashes were found to increase by 155 percent after cable barrier installation. A detailed analysis of crashes involving a cable barrier strike found the barriers were 96.9 percent effective in preventing penetration through the barrier. Weather conditions, horizontal curvature, and offset of cable barrier from the roadway were also
Paleozoic sedimentation and Caledonian terrane architecture in NW Svalbard: indications from U–Pb geochronology and structural analysis

Svalbard's Northwestern Basement Province is traditionally divided into the Albert I Land and the Biscayarhalvøya terranes. New U–Pb age data on zircon and monazite and structural and geochemical data provide first evidence of early Paleozoic deposits south of the Biscayarhalvøya Terrane indicating the possible existence of a third terrane: the Germaniahalvøya Terrane. This area is represented by a Cambro-Ordovician succession of mica schist and marble (Lernerøyane Group) and its higher-grade metamorphic equivalent (Liefdefjorden Migmatite Complex), which were affected by the Taconian phase (migmatization at c. 469 Ma) and the Scandian phase (c. 422–415 Ma) of the Caledonian Orogeny. During the Scandian phase, the ductile Lerner Deformation Zone was formed. New isotopic data from the eclogite-bearing Richarddalen Complex of the Biscayarhalvøya Terrane imply the formation as an Ordovician–Silurian collision-related mélange dominantly composed of c. 730 to 600 Ma Timanian island-arc-derived detritus and igneous rocks, partly eclogite-facies metamorphosed at c. 656 Ma, and Tonian meta-igneous rocks. After amphibolite-facies metamorphism of the mélange matrix at c. 423 Ma, the Richarddalen Complex and the Stenian–Tonian Biscayarfonna Group were juxtaposed and mylonitized by the dextral Biscayarhalvøya Deformation Zone. Supplementary material: The complete geochemical and U-Pb isotope geochemical dataset as well as additional figures are available at https://doi.org/10.6084/m9.figshare. c.5778735
Surface and subsurface water balance estimation by the groundwater recharge model and a 3-D two-phase flow model/Estimation de bilan hydrologique de surface et de subsurface à l’aide de modèles de recharge de nappe et d’écoulement diphasique 3-D

Abstract Abstract Land development often results in adverse environmental impact for surface and subsurface water systems. For areas close to the coast, land changes may also result in seawater intrusion into coastal aquifers. Due to this, it is important to evaluate potential adverse effects in advance of any land development. For evaluation purposes a combined groundwater recharge model is proposed with a quasi three-dimensional unconfined groundwater flow equation. The catchment water balance for a planned new campus area of Kyushu University in southern Japan, was selected as a case study to test the model approach. Since most of the study area is covered with forest, the proposed groundwater recharge model considers rainfall interception by forest canopy. The results show that simulated groundwater and surface runoff agree well with observations. It is also shown that actual evapotranspiration, including rainfall interception by forest canopy, is well represented in the proposed simulation model. Several hydrological components such as direct surface runoff rate, groundwater spring flow rate to a ground depression, trans-basin groundwater flow etc., were also investigated.
Exploring the Use of Player Load in Elite Soccer Players

Background: The aims of this study were to (1) analyze the distribution of the player load (PLTOTAL) in 3 axes of movement (PLAP, anterior-posterior; PLML, medial-lateral; PLV, vertical) during elite soccer matches, (2) investigate the effect of playing position on PL-related variables, and (3) explore the association between PLTOTAL and distance covered by the players. Hypothesis: Despite different load distribution between axes of movement, PLTOTAL might be used as a body load indicator for all playing positions. Study Design: Longitudinal study. Level of Evidence: Level 3. Methods: Data were collected from elite soccer players using WIMU Pro tracking systems, which included inertial sensors. Results: The axis of movement had a significant effect on the distribution of the load (P < 0.001; conditional R2 = 0.91), with the greatest contribution from the PLV (P < 0.001; d = 5.41-5.86). Moreover, no effect of playing position on PLTOTAL, PLV, PLML, or PLAP was observed (P > 0.05). Finally, a large correlation was found between PLTOTAL and distance covered, and the linear mixed model showed that distance may be predicted by the PLTOTAL (conditional R2 = 0.81; P < 0.001). Conclusion: Differences in load distribution were based on the axis of movement, although playing position had no effect on any variable. The selection of either distance covered, which is representative of a 2-dimensional analysis, or PLTOTAL, which is representative of a 3-dimensional analysis, may be adequate for monitoring locomotor demands or accelerometer-derived load. Clinical Relevance: Training strategies that focus on the vertical component of match play should be adopted. In addition, given that PLTOTAL is an accelerometry-based metric, which combines the accelerations in anterior-posterior, medial-lateral, and vertical planes, strength and conditioning coaches may use this parameter as a measure of total body load.
Short Communication: Fish diversity and its relationship with environmental variables in Kamala River, Nepal

Ghimire S, Koju NP. 2021. Short Communication: Fish diversity and its relationship with environmental variables in Kamala River, Nepal. Biodiversitas 22: 4865-4871. Kamala River originates from the lower part of the Mahabharat range and flows through inner to outer Terai, providing a broad range of ecosystem services; provisioning, regulating, supporting, and cultural. However, the information regarding the environmental factors and species diversity in the river is not available enough. Hence the study aimed to explore baseline information on the diversity and abundance of fish and their relation to environmental variables. The fish diversity was assessed in five sections of Kamala River and correlated with different environmental variables. The study was carried out during September-October 2019, marking the post-monsoon season of Nepal. Fish samples were collected using cast nets, and physiochemical parameters were analyzed onsite and in the laboratory. Altogether 19 freshwater fish species belonging to 5 orders, 8 families, and 15 genera were recorded. Cyprinids were the most dominant in the river, while Channids, Mastacembelids, Botiids, Sisorids, Gobiids were represented less. The Redundancy Analysis (RDA) ordination method revealed that species variation was correlated with temperature, Electrical Conductivity (EC), Total Dissolved Solids (TDS), and nitrate. Nonetheless, different river sections were disturbed due to mining, deforestation, and construction activities, which could pose a real threat to fish diversity and population, and other aquatic organisms.
Identification of a key regulatory pathway in bone regeneration using a novel mouse fracture model

OF THE DISSERTATION IDENTIFICATION OF A KEY REGULATORY PATHWAY IN BONE REGENERATION USING A NOVEL MOUSE FRACTURE MODEL By Michaele Beth Manigrasso Dissertation Director: James Patrick O’Connor, PhD Fracture healing is the complex biological process that restores broken bones to their original shape and function. While the fracture repair process follows a definitive sequence of events, not all the molecular or chemical pathways are completely understood. The development of animals with targeted mutations has allowed for the examination of specific fracture healing pathways, making the use of the mouse model an increasingly valuable tool in the field of orthopaedics. Additionally, evaluating the healing tissues using a torsional mechanical testing protocol is more reproducible and provides a better estimate of the biomechanical properties. Therefore, the first section of this dissertation is focused on the development and characterization of a murine femoral fracture model suitable for torsional mechanical testing. The model developed was tested using radiography, histology and mechanical testing and was shown to be
Effects of certain Insecticides against Diamondback Moth, Plutella xylostella (L.) on Cabbage under Field Condition

Two field trials were carried out during the Rabi seasons of 1998–99 and 1999–2000 at the experimental farm of Division of Entomology, IARI, New Delhi, to assess the bioefficacy of different synthetic insecticides against diamondback moth, Plutella xylostella (L.) on cabbage. The bioefficacy of insecticides in a descending order was: cartap hydrochloride (0.05%) > lambda cyhalothin (0.01%) > beta cyfluthrin (0.00125%) > ethofenprox (0.01%) > endosulfan (0.07%) > imidacloprid (0.01%). Cartap hydrochloride, thus, proved most effective against P. xylostella.
Cu(II) Binding Increases the Soluble Toxicity of Amyloidogenic Light Chains

Light chain amyloidosis (AL) is caused by the aberrant overproduction of immunoglobulin light chains (LCs). The resulting abnormally high LC concentrations in blood lead to deposit formation in the heart and other target organs. Organ damage is caused not only by the accumulation of bulky amyloid deposits, but extensive clinical data indicate that circulating soluble LCs also exert cardiotoxic effects. The nematode C. elegans has been validated to recapitulate LC soluble toxicity in vivo, and in such a model a role for copper ions in increasing LC soluble toxicity has been reported. Here, we applied microscale thermophoresis, isothermal calorimetry and thermal melting to demonstrate the specific binding of Cu2+ to the variable domain of amyloidogenic H7 with a sub-micromolar affinity. Histidine residues present in the LC sequence are not involved in the binding, and yet their mutation to Ala reduces the soluble toxicity of H7. Copper ions bind to and destabilize the variable domains and induce a limited stabilization in this domain. In summary, the data reported here, elucidate the biochemical bases of the Cu2+-induced toxicity; moreover, they also show that copper binding is just one of the several biochemical traits contributing to LC soluble in vivo toxicity.
Application of a spreadsheet hydrological model for computing the long-term water balance of Lake Awassa, Ethiopia

Abstract The water balance of the closed freshwater Lake Awassa was estimated using a spreadsheet hydrological model based on long-term monthly hydrometeorological data. The model uses monthly evaporation, river discharge and precipitation data as input. The net groundwater flux is obtained from model simulation as a residual of other water balance components. The result revealed that evaporation, precipitation, and runoff constitute 131, 106 and 83 × 106 m3 of the annual water balance of the lake, respectively. The annual net groundwater outflow from the lake to adjacent basins is 58 × 106 m3. The simulated and recorded lake levels fit well for much of the simulation period (1981–1999). However, for recent years, the simulated and recorded levels do not fit well. This may be explained in terms of the combined effects of land-use change and neotectonism, which have affected the long-term average water balance. With detailed long-term hydrogeological and meteorological data, investigation of the subsurface hydrodynamics, and including the effect of land-use change and tectonism on surface water and groundwater fluxes, the water balance model can be used efficiently for water management practice. The result of this study is expected to play a positive role in future sustainable use of water resources in the catchment.
Identification and Introgression of Bacterial Blight Resistance From African Rice (Oryza Glaberrima Steud.)

Bacterial blight (BB) caused by Xanthomonas oryzae pv. oryzae (Xoo) is one of the major diseases affecting rice production. In the present study, 31 accessions of O. glaberrima were screened for BB resistance consecutively for four seasons and identified 28 stable BB resistant accessions with a mean lesion length of < 3cm. Molecular characterization revealed absence of xa5, xa13, Xa21, Xa38, xa41(t) and xa45, indicating the possibility of presence of novel gene(s) conferring BB resistance. In order to transfer BB resistance from O. glaberrima, resistant accession EC861812 was crossed to the susceptible cultivar, IR64 and BC2F2 population developed. Genetic studies in BC2F2 population showed transgressive segregation which indicates that O. glaberrima also harbor beneficial alleles for yield related traits. Six resistant BC2F2 plants with mean lesion length of 0.1-0.8 cm were genotyped with 70 parental polymorphic SSR markers which revealed recurrent parent genome 65.1 to 84.5% with average of 67.5%. The BB resistant introgression lines identified in the present study will serve as pre-breeding lines for mapping of BB resistance derived from O. glaberrima.
Levels of Trace Elements in Erythrocytes as Endocrine Disruptors in Obese and Nonobese Women with Polycystic Ovary Syndrome

Introduction: Polycystic ovary syndrome (PCOS) is one of the most commonly recognized endocrinopathies in women. The literature lacks clear data that allow any meaningful conclusions to be drawn about the influence of trace elements in erythrocytes on the biochemical parameters of PCOS. Materials and methods: This study was conducted among 47 women meeting the Rotterdam criteria for the diagnosis of polycystic ovary syndrome. The research groups included women with PCOS with different BMI values (body mass index): obese women with PCOS (PCOS with BMI ≥ 30, mean BMI index 35.4 ± 4.4 kg/m2), nonobese PCOS women (PCOS with BMI < 30, mean BMI index 25.2 ± 2.8 kg/m2), and healthy control group (CG) with a mean BMI of 23.57 ± 0.9 kg/m2. The contents of trace elements in erythrocytes were determined with an inductively coupled plasma atomic emission spectrometer. Results: The only trace element showing significant differences in concentration between the studied groups was nickel (Ni). The level of nickel in the obese women with PCOS (BMI ≥ 30) was significantly higher than in nonobese women (BMI < 30). The content of other trace elements in erythrocytes did not differ significantly between the studied groups. Several significant correlations were found within each of the studied PCOS groups: in the group of obese women, the content of zinc (Zn) in erythrocytes positively correlated with prolactin, the content of magnesium (Mg) positively correlated with testosterone, and the content of manganese (Mn) negatively correlated with thyroid-stimulating hormone. In the group of nonobese women, Zn content correlated positively with testosterone, Ni with luteinizing hormone (LH) and estradiol, and Mg negatively correlated with estradiol. Conclusions: The relationship between the level of trace elements and the level of hormones suggests that, in obese women with PCOS, nickel may play a role in inhibiting the processes of folliculogenesis and ovulation. Research on trace elements and their relationship to ovulatory cycles and the development of PCOS may contribute to reducing the consequences of PCOS and, therefore, should be extended.
Precision measurement of the top quark mass with single top events at CMS

A measurement of the top quark mass in single top events produced in the C-channel at the CMS experiment is presented. The C-channel is the dominant process for single top quark production at the LHC. The C-channel process provides a unique phase space with different color reconnection conditions than that of tt̄ events, which are are exploited for the most precise measurements of the top-quark mass. The final state comprises a single top quark along with a light quark giving rise to at least two jets, (one of which arises from the hadronization of a b quark), an isolated high-momentum lepton (electron or muon), and large missing transverse momentum due to an escaping neutrino from the W boson decay. The study is based on proton-proton collision data, equivalent to 35.9 fb−1 integrated luminosity, recorded at √ B = 13 TeV by the CMS experiment during 2016. Dominant standard model backgrounds are studied in different kinematic regions depending on the number of b-tagged quarks and light-flavor jets in the final state. A multivariate technique relying on boosted decision trees is employed to optimally separate the signal from backgrounds. The top quark mass is reconstructed using kinematic information of the final-state objects, namely the charged lepton, missing transverse momentum, and jets. We obtain the top quark mass <t = 172.13+0.69 −0.70 GeV, by fitting the reconstructed mass distribution using an appropriate combination of parametric shapes.