Miracle-dz/UniFAR-FTUs huggingface dataset:
Flash: E � icient Dynamic Routing for O � chain Networks

O � chain networks emerge as a promising solution to address the scalability challenge of blockchain. Participants make payments through o � chain networks instead of committing transactions on-chain. Routing is critical to the performance of o � chain networks. Existing solutions use either static routing with poor performance or dynamic routing with high overhead to obtain the dynamic channel balance information. In this paper, we propose Flash, a new dynamic routing solution that leverages the unique transactions characteristics in o � chain networks to strike a better tradeo � between path optimality and probing overhead. By studying the traces of real o � chain networks, we � nd that the payment sizes are heavy-tailed, and most payments are highly recurrent. Flash thus di � erentiates the treatment of elephant payments from that of mice payments. It uses a modi � ed max-� ow algorithm for elephant payments to � nd paths with su � cient capacity, and strategically routes the payment across paths to minimize the transaction fees. Mice payments are sent directly by looking up a routing table with a few precomputed paths to reduce probing overhead. Testbed experiments and trace-driven simulations show that Flash improves the success volume of payments by up to 2.3x compared to the state-of-the-art routing algorithm.
Chicken Anaemia Virus in Egyptian Broiler; Clinical Signs and Molecular Characterization

A total of 18 flocks , 45 day old broiler from Ismailia, Egypt were tested for chicken anemia virus (CAV) using serological evidence and molecular characterization. Tested birds had history of diarrhea, blue wing, depression, and deaths. Necropsy findings were pale liver, severe atrophy of bursa Fabricius and thymus, pale discoloration of the bone marrow and subcutaneous hemorrhages. The viral DNA of the VP1 gene was detected and sequenced. Nucleic acid alignment showed 100% similarities with many CAV viruses. Antibodies against CAV were detected in 73.9% of the tested samples using commercial ELISA kit. Hemoglobin (Hb) revealed low percentage (4.3% to 8.02%), and packed cell volume (PCV) were measured and showed anemic level (22.5 to 34.2). The data strengthen the concept that CAV may have a negative economic impact on the chicken industry in Ismailia.
10Be/9Be Ratios Reveal Marine Authigenic Clay Formation

As reverse weathering has been shown to impact long‐term changes in atmospheric CO2 levels, it is crucial to develop quantitative tools to reconstruct marine authigenic clay formation. We explored the potential of the beryllium (Be) isotope ratio (10Be/9Be) recorded in marine clay‐sized sediment to track neoformation of authigenic clays. The power of such proxy relies on the orders‐of‐magnitude difference in 10Be/9Be ratios between continental Be and Be dissolved in seawater. On marine sediments collected along a Chilean margin transect we chemically extracted reactive phases and separated the clay‐sized fraction to compare the riverine and marine 10Be/9Be ratio of this fraction. 10Be/9Be ratios increase fourfold from riverine to marine sediment. We attribute this increase to the incorporation of Be high in 10Be/9Be from dissolved biogenic opal, which also serves as a Si‐source for the precipitation of marine authigenic clays. 10Be/9Be ratios thus sensitively track reverse‐weathering reactions forming marine authigenic clays.
The Mediating Role of Organizational Learning and Knowledge Sharing in the Relationship between Culture and Organizational Innovation

Any organization needs to innovate in order to survive in today's turbulent and changing world. Understanding the changes in the surrounding environment, looking for innovative and innovative responses, cannot be achieved unless it is institutionalized in the sponsoring culture of the organization. And the organization becomes a learning organization using the flow of knowledge. The present study aims to investigate the relationship between organizational culture, knowledge sharing, organizational learning and innovation. The research population consists of all knowledge workers in the Education Organization of Fars province, from which 190 people were selected as samples using the non-random targeted sampling method. The research data was collected by distributing questionnaires among samples. After collecting data, the distribution of the data related to the variables was examined using the Kolmogorov–Smirnov test; then, the Pearson’s correlation coefficient and structural equation modeling were used to test the research hypotheses. The results of this study show that there is a significant relationship between variables of organizational culture, knowledge sharing, organizational learning and organizational innovation. Also, the results of examining the components of organizational culture demonstrated that adhocracy and clan cultures have positive effects on other variables while hierarchy and market cultures negatively affect the dependent variables. As well as the role of mediator between organizational culture and organizational learning, knowledge sharing and organizational innovation proven. On the other hand, it was found that knowledge sharing can also play the role of mediator between organizational culture and innovation.
The Impact of Economic Policy Uncertainty on Capital Structure: Evidence from Russia

This paper is a study of the influence of economic policy uncertainty on the capital structure of companies operating in the Russian market. The sample size is particularly notable (over 16,000 companies and 230,000 observations are included) insofar as previous studies have invariably used smaller selections due to the complexities of data processing. Several hypotheses are proposed and treated which concern the interrelations between company debt policies and the status of individual, sectoral, or industry relevant commercial activity, where the constant threat of economic uncertainty due to political or other external machinations affects the market. This research paper examines the following capital structure determinants: profitability, asset structure, company size, tax shield, non-debt tax shield, growth opportunity, and risk. The following methods are applied to test a series of nine hypotheses proposed as the most salient indicators of the present state of academic consensus: the Pool model (Pool), the fixed effect model (FE), and the random effect model (RE). In this context, the influence of economic uncertainty on the status of different debt types in 16,882 Russian companies between 2000 and 2017 was studied using the economic policy uncertainty index calculated in 2012. The results serve to confirm many of the extant hypotheses in the academic literature in the area of capital structural evaluation. For example, it is immediately apparent that the influence of uncertainty is of less significance for large companies as regards all types of debt (joint, short-term and long-term), due to their greater stability and lower risks for creditors. Among other conclusions, it is confirmed that as long as serious government participation is characteristic of the Russian banking system, the efficacy of the debt financing system is not equal for all sectors, and those sectors which are of strategic importance for the state are particularly resilient in troubled economic periods. However, interestingly, in the case of a short-term debt leverage such influence does not materialise. From a theoretical point of view this paper will be useful for researchers studying the fluctuating market conditions of developing or transitional markets (the large sample size will make this study particularly attractive for further evaluation at all levels of academic analysis). An understanding of the multivariate interrelations described in this paper may also be useful to company managers and investors who will gain insight into the consequences of fluctuations in levels of economic uncertainty for different types of companies.
Modulation of Adipose-Derived Mesenchymal Stem/Stromal Cell Transcriptome by G-CSF Stimulation

Mesenchymal stem/stromal cells (MSCs) exhibit multidifferentiation potential, paralleled with immunomodulatory and trophic properties that make them viable alternative tools for the treatment of degenerative disorders, allograft rejection, autoimmune diseases, and tissue regeneration. MSC functional attributes can be modulated by exposing them to inflammatory-stimulating microenvironments (i.e., priming) before their therapeutic use. Granulocyte-colony stimulating factor (G-CSF) is a cytokine that plays key roles in immune response and hematopoiesis modulation through direct effects on hematopoietic progenitors' proliferation, survival, and mobilization. Despite the established roles of MSCs supporting hematopoiesis, the effects of G-CSF on MSCs biology have not been thoroughly explored. This study reveals that G-CSF has also direct effects on adipose-derived MSCs (ADSCs), modulating their functions. Herein, microarray-based transcriptomic analysis shows that G-CSF stimulation in vitro results in modulation of various signaling pathways including ones related with the metabolism of hyaluronan (HA), conferring a profile of cell mobilization to ADSCs, mediated in a cell-intrinsic fashion in part by reducing CD44 expression and HA synthesis-related genes. Collectively, these data suggest a direct modulatory effect of G-CSF on ADSC function, potentially altering their therapeutic capacity and thus the design of future clinical protocols.
Morphometric evaluation of palate for sexual dimorphism in Kashmiri population

Background: Bones and teeth are parts of human body which are most resistant to decomposition. Owing to the highly mineralized biological composition of these structures, they tend to be indispensable in terms of forensic evidence. Morphometry of skeleton is one of the many methods used for sexual dimorphism in cases of forensic background. Palatal morphometry has been widely implicated for this purpose in various populations. This study was aimed at establishment of sexual dimorphism in Kashmiri population based on palatal morphometric indices. Methodology: An in vitro study was carried out on maxillary casts of 130 patients (65 males & 65 females). Morphometric landmarks were marked on the cast to measure the parameters of anterior arch length, total arch length and palatal width for both male & female groups. Results: Students t-test was carried out for comparative analysis. Males were found to have significantly higher values in terms of total arch length & palatal width. However, anterior arch length did not show significant difference among males and females. Conclusion: The study concluded that palatal morphometric indices can be used as an adjunctive method for establishing sexual dimorphism in Kahmiri population.
Theories Linking Capital Structure with Financial Performance 2018

Maximizing firms’ shareholder wealth is an important duty of finance businesses’ managers. Scholars argue whether this goal can be reached through capital structure choices. To make this possible, firms should minimize their cost of capital and provide a return which adequately provides for the risk taken by shareholders and above the opportunity cost (Jahanzeb, 2013). Originally, Modigliani and Miller (1958) proposed that in a perfect market, capital structure is irrelevant and does not affect a firm’s value as explained in more detail in the following section. Previously, there were extensive discussions in literature on: First, the optimum capital structure choices and determinants; and second, the impact of capital structure on firms’ value and performance (Allen et al., 2013; Berger, 1995; Frank and Goyal, 2007; Myers, 1984). Following Modigliani-Miller (M&M) theory, several other theories were developed based on the assumption of the perfect market. First, trade-off theory contended that firms trade-off between the benefits and costs of using debt and equity as a source of financing when considering market imperfections, for example, taxes, bankruptcy cost, and agency cost (Luigi and Sorin, 2009). Second, pecking order theory pioneered by Myers and Majluf (1984) looked at the issue of asymmetric information between shareholders and firms’ managers. The main goal of this theory is to minimize the problem of asymmetric information using internal sources as a first choice. If internal Abstract
SHORT-TERM SAFETY AND BENEFICIAL EFFECTS OF HYDROXYUREA THERAPY IN CHILDREN WITH SICKLE CELL DISEASE

Anand Suresh Somkuwar1, Chandrakant M Bokade2, Saira Merchant2, Rajkumar Meshram3, Manisha Mahalinge4, Tushar Suresh Somkuwar5 From 1Senior Resident, 2Professor, 3Associate Professor, Department of Pediatrics, 4Senior Resident, Department of Pathology, 5Senior Resident, Department of Radiology, Government Medical College, Nagpur, Maharashtra, India Correspondence to: Dr. Anand Suresh Somkuwar, Department of Pediatrics, Government Medical College, Nagpur 440003, Maharashtra, India. E-mail: somkuwar761@gmail.com Received 28 November 2019 Initial Review 11 December 2019 Accepted 30 December 2019
EFFICACY OF DIETARY VITAMIN C, E AND THEIR COMBINATION ON EGG PRODUCTION AND EGG QUALITY OF DOKKI-4 LAYING HENS DURING EGYPTIAN SUMMER SEASON

An experiment was conducted to study the effects of adding vitamin C (L-ascorbic acid), vitamin E (µ- tocopherol acetate ) and their combination to diets on productive performance, egg quality and some blood plasma constituents of Dokki-4 laying hens during summer season in Egypt. The experimental period lasted from June to September, 2010. A total of 120, 30 weeks old Dokki-4 hens were randomly divided into four equal groups, each contained 3 equal replications. First group was fed a basal diet (control group). The other groups were fed the basal diet supplemented with 250 mg vitamin C/ kg diet (group 2),150 mg vitamin E /kg diet (group 3) and 250 mg vitamin C plus 150 mg of vitamin E (group 4). The results indicated that supplementation of the basal diet with the combination of vitamin C and E (group 4) resulted in positive effects on final body weight, egg production, egg weight, egg mass, feed intake and yolk index as compared to those of the control group. However, feed conversion was numerically improved for the birds received the vitamin supplemented diets as compared to the control hens. Shell thickness was significantly (P≤0.05) improved with adding vitamin E alone or in combination with vitamin C as compared to their control counter parts. Blood Plasma protein was significantly increased in hens given vitamin C alone or in combination with vitamin E compared with their controls Plasma cholesterol concentration was significantly decreased, whereas plasma levels of calcium and phosphorus were significantly increased response to dietary single and combined addition of vitamins C and E as compared to those of the control group. Dietary supplementation with 250 mg ascorbic acid plus 150 mg vitamin E proved to be an effective practice for alleviating the adverse effects of heat stress on Dokki-4 laying hens during summer season in Egypt.
Geodia and other massive sponges on Atlanto-Arctic upper bathyal mixed sediment MarLIN – Marine Life Information Network Marine Evidence – based Sensitivity Assessment ( MarESA ) Review

This review can be cited as: Last, E.K. , Ferguson, M. , Serpetti, N. , Narayanaswamy, B.E. , Hughes, D.J. 2020. [Geodia] and other massive sponges on Atlanto-Arctic upper bathyal mixed sediment. In Tyler-Walters H. and Hiscock K. (eds) Marine Life Information Network: Biology and Sensitivity Key Information Reviews, [on-line]. Plymouth: Marine Biological Association of the United Kingdom. DOI https://dx.doi. org/10.17031/marlinhab.1199. 1
The cost-effectiveness of the adherence improving self-management strategy (AIMS) in HIV-care: a Markov model

Background: Non-adherence to medication is an important cause of poor health and increased health care consumption. The Adherence Improving self-Management Strategy (AIMS) is a nurse-delivered intervention that fits in routine clinical care. Previous trials demonstrated that AIMS is effective but no study has yet estimated the long-term cost-effectiveness of AIMS. The objective of this study was to estimate the cost-effectiveness of AIMS compared with treatment-as-usual (TAU) in HIV-care Methods: A lifetime Markov model was developed using 13 health states (ranging from undetectable viral load and high CD4-cell count, to death). The natural course of illness for HIV-patients receiving TAU was calculated based on a longitudinal dataset from >7.000 patients. Health care consumption, HIV transmission risks, quality of life, and productivity costs were computed for each health state. The effect of AIMS on probability transitions was computed as relative risks, and was derived from a recent multi-centre RCT comparing AIMS with TAU. Incremental cost-effectiveness ratios for a base-case and several sensitivity scenarios were estimated. Findings: The base case and sensitivity scenarios showed that AIMS was dominant to TAU: lower costs and more effective. The incremental quality adjusted life years varied between 0.022 and 0.049, and the incremental costs varied from €-226 to €-1777. These results are robust for changes in important model parameters. Discussion: The current study demonstrates that AIMS is one of the first adherence interventions to be cost-effective and even cost-saving. AIMS should from a clinical and economic perspective be considered for adoption in routine clinical care for HIV.
Quantitative scar assessment using cardiac magnetic resonance imaging to predict ventricular arrhythmia risk and cardiac resynchronisation response

2 List of Figures . 9 List of Tables . 14 List of Abbreviations . 16 Acknowledgment . 18 Chapter 1 Thesis Outline . 20 1.1 Thesis Aims . 20 1.2 Chapter Overview . 20 Chapter 2 Introduction . 23 2.1 Principles of cardiac magnetic resonance imaging . 23 2.1.1 Basic physics of MRI . 23 2.1.2 T1 and T2 relaxation . 25 2.1. 3 Cardiac and respiratory motion compensation . 26 2.2 Inversion recovery sequences and late gadolinium enhancement for myocardial scar imaging . 28 2.3 Grey zone . 29 2.4 T1 mapping . 30 2.5 Relevance of myocardial scar to ventricular arrhythmia . 35 2.6 Relevance of myocardial scar to cardiac resynchronisation therapy response. 37 Chapter 3 General Methods . 41 3.1 Ethics . 41 3.2 Patient selection . 41 3.3 Cardiac magnetic resonance imaging . 42 3.3.1 CMR protocol . 42 3.3.2 Image analysis . 43 3.4 Echocardiography . 44 3.5 Activation recovery interval measurement . 45 3.6 Statistics . 46
Predicting the Evolution of the 2014–20...le of Coupled Global Climate Forecasts

Citation: Jacox MG, Tommasi D, Alexander MA, Hervieux G and Stock CA (2019) Predicting the Evolution of the 2014–2016 California Current System Marine Heatwave From an Ensemble of Coupled Global Climate Forecasts. Front. Mar. Sci. 6:497. doi: 10.3389/fmars.2019. 00497 Predicting the Evolution of the 2014–2016 California Current System Marine Heatwave From an Ensemble of Coupled Global Climate Forecasts
ROLE OF BOSWELLIC ACID IN THE TREATMENT OF PEPTIC ULCER DISEASE

A peptic ulcer is a chronic disease. Its main features are the incompetent defense of the mucosal and the existence of the gastric juice. The two most important factors that disrupt the balance between the acid and the mucus are the Helicobacter pylori infection (H. pylori) and Non-steroidal anti-inflammatory drugs (NSAIDs). The known treatments like proton pump inhibitors (PPIs) and histamine-2 (H2) receptor antagonists have demonstrated adverse effects and various drug interactions. So the desired approach nowadays is alternative therapies and the usage of herbal products. Boswellic acids provide a potential alternative to the treatment of non-steroidal anti-inflammatory drugs induced peptic ulcer.
Leptospirosis in slaughtered cows in the Triangulo Mineiro, Minas Gerais: prevalence, serological profile and renal lesions

Leptospirosis is a zoonosis that affects several species of domestic and wild animals and is an important cause of economic losses in cattle in Brazil. In this study, we determined the prevalence of bovine leptospirosis in the Triângulo Mineiro region, Minas Gerais, Brazil, identified the most frequent serovars of Leptospira interrogans, and examine the renal pathological changes associated with the disease. Samples of blood serum and kidney fragments from 100 bovine females were collected in cattle abattoir. In the serological investigation 48% of the cows were positive. The serovars for which there were more reactive animals were Wolffi (24%), Hardjo (21%) and Hebdomadis (18%). Among the positive samples, 14/48 showed antibody titers greater than 1:100, and 70.83% of the seropositive animals responded to more than one Leptospira interrogans serovar. Only one farm did not have seropositive cows and in nine farms studied, six (66.66%) presented seropositive animals to the Hebdomadis serovar. At the histopathological examination, the most frequent microscopic lesions in positive animals were hyalinization (81.25%), congestion (81.25%) and hydropic degeneration (70.83%). However, these histopathological alterations were also found in kidneys of animals negative to serology, such as hyalinization (80.77%), congestion (48.07%) and hydropic degeneration (55.77%) and these findings are unrelated to positivity. Histopathological examination of the kidneys is not indicated to replace the serological diagnosis of leptospirosis, and may be used only as a complementary examination. Despite the low frequency of seropositive animals in the Triângulo Mineiro region, the disease is present in a large number of farms. Noteworthy is the high frequency of serovar Hebdomadis and it can be considered an emerging serovar in the region. The evaluation of the frequency of this serovar in other regions becomes important, and once verified should result in the recommendation of the inclusion of this serovar in the leptospirosis control.
Personality Types as Correlate of Specific Phone Usages and Smart Phone Addiction among Students in the University of Ilorin, Kwara State, Nigeria

Past researchers have examined the impact of personality types on technology usage among students from varying angles. However, due to dearth of studies on personality types and smart phone addiction among students in the Nigerian environment, this study investigated the relationship between personality types, smart phone addiction and specific phone usages among University students. A sample size of 200 was used for this study using systematic sampling technique in the selection of respondents in the study area. Findings revealed that conscientiousness and agreeableness personality types had significant positive correlation with smart phone addiction; while extraversion and neuroticism had significant negative correlation with smart phone addiction. Again personality types had significant positive and negative correlation with specific phone usages. In addition, findings revealed that majority of the specific phone usages had positive correlation with smart phone addiction. Based on the findings of this study, recommendations were made towards curbing addictive tendencies among university students in the use of smart phones.