Miracle-dz/UniFAR-FTUs huggingface dataset:
Impact of digital dermatitis on locomotion and gait traits of beef cattle

Abstract Digital dermatitis (DD) is an infectious skin disease and a major cause of lameness that significantly impacts cattle productivity and welfare. However, DD does not always result in lameness and lameness scoring systems are not specific to hoof pathologies. Digital dermatitis detection protocols could be improved by including gait traits most related to DD. The aims of this study were to 1) determine the association between DD M-stage (“M” for Mortellaro), locomotion, and gait traits: arched back (AB), asymmetric gait (AG), head bobbing (HB), tracking up (TU), and reluctance to bear weight (WB), and 2) determine which traits are most associated with DD. Cattle (n = 480) from three feedlots were enrolled. Locomotion score (LS) and gait traits were assessed as cattle walked four strides along a dirt alleyway. Next, cattle were restrained in a chute, each hind foot lifted, and DD M-stage (absent, active, or chronic) determined. The association between presence of DD, LS, and gait traits were scored independently (n = 291). For both LS and gait the lowest score represents normal and the highest score severely altered. Digital dermatitis presence was associated with higher LS (P < 0.001). Odds ratios (ORs) for cattle with DD being lame or moderately to severely lame were 8.0 (P < 0.001) and 10.1 (P < 0.001) times more than cattle without lesions. Cattle with active lesions had the greatest odds of being lame (OR = 9.4; P < 0.001). Digital dermatitis presence was associated with all gait traits (P < 0.001), where AG (OR = 5.5; P < 0.001) and WB (OR = 5.8; P < 0.001) had the greatest OR for classifying cattle with DD as having altered gait. The OR for cattle with active lesions having altered gait was greatest for WB which was 6.0 (P < 0.001) times greater than cattle without lesions. The OR for cattle with chronic lesions having altered gait was greatest for AG being 6.5 (P < 0.001) times more than cattle without lesions. All gait traits had low sensitivity (Se) for detecting cattle with DD and varied from 6.7% to 55.8%. Locomotion score (Se 55.8%) and AG (Se 44.2%) were most predictive with positive predictive values of 76.6% and 74.3%, respectively. Specificity for all traits ranged from 94.1% for LS to 98.4% for WB with negative predictive values of 72.1% and 68.9%, respectively. In conclusion, LS, WB, and AG had the strongest association with cattle that had DD. Locomotion scoring that includes a focus on WB and AG is the best tool to detect DD in beef cattle.
Risk factors for suicidal attempt in patients with the melancholic subtype of depressive disorder: Implication for nursing care

The incidence of suicide in patients with depressive order is much higher than other population. We aimed to evaluate the current status and risk of suicidal attempt in patients with the melancholic subtype of depressive disorder, to provide evidence for the clinical management and nursing care of depressive disorder. Patients diagnosed as the melancholic subtype of depressive disorder and treated in our hospital from June 1, 2018 to August 31, 2021 were included. The characteristics of included patients were collected and analyzed. Pearson correlation analysis and logistic regression analysis with odd ratio and 95% confidence interval were conducted to analyze the influencing factors of suicidal attempt in patients with the melancholic subtype of depressive disorder. A total of 446 patients with melancholic subtype of depressive disorder were included, the incidence of suicidal attempt was 18.83%. Pearson correlation analysis indicated that gender (R = 0.611), alcohol drinking (R = 0.719), living situation (R = 0.812), number of previous admission to hospital (R = 0.547), sleep disorder (R = 0.612) and frequent depressive episodes (R = 0.559) were all correlated with the suicidal attempt in patients with melancholic subtype of depressive disorder (all P < 0.05). Logistic regression analysis showed that female (OR 3.115, 95%CI 2.493–3.906), alcohol drinking(OR 1.946, 95%CI 1.684–2.763), living alone (OR 2.401, 95%CI 1.915–3.008), number of previous admission to hospital ≥ 3 (OR 2.342, 95%CI 1.601–2.742), sleep disorder (OR 1.821, 95%CI 1.328–2.215) and frequent depressive episodes (OR 3.128, 95%CI 2.421–3.779) were the independent risk factors of suicidal attempt (all P < 0.05). Suicidal attempt is common in the patients with melancholic subtype of depressive disorder, and there are many related risk factors for suicidal attempt in patients with the melancholic subtype of depressive disorder.
Dental structure and tooth attachment modes in the common fangtooth Anoplogaster cornuta (Valenciennes, 1833) (Actinopterygii; Trachichthyiformes; Anoplogastridae)

We studied the structure and attachment modes of the teeth of adult Anoplogaster cornuta using light- and scanning-electron microscopic techniques. All teeth were monocuspid, composed solely of orthodentin, and lacked a covering enameloid cap. Fourteen teeth were present in the oral jaws, with three teeth each on the left and right premaxilla and four teeth each on the left and right dentary. The anteriormost premaxillary and dentary teeth were considerably larger than the more posteriorly located ones. The oral jaw teeth were transparent, non-depressible and firmly ankylosed to their respective dentigerous bone by a largely anosteocytic bone of attachment. No evidence for replacement of the large oral jaw teeth was found in the analyzed adult specimens. The bone of attachment exhibited lower calcium and phosphorus concentrations and a higher Ca/P ratio than the orthodentin. The connection between dentinal tooth shaft and bone of attachment was stabilized by a collar of mineralized collagen fibers. In contrast to the oral jaw teeth, the pharyngeal teeth exhibited a ring-like fibrous attachment to their supporting bones. This mode of attachment provides the teeth with some lateral mobility and allows their depression relative to their supporting bones, which may facilitate intra-pharyngeal prey transport. In contrast, a firm ankylosis was observed in numerous small teeth located on the branchial arches. The function of these teeth is presumably to increase the tightness of the pharyngeal basket and thereby the retention of small prey items in a species living in a habitat with only sparse food supply. Our findings corroborate earlier statements on the tooth attachment modes of the oral jaw teeth of Anoplogaster cornuta, but provide new findings for the attachment modes of pharyngeal teeth in this species.
Epidemiology of Lyme borreliosis based on outpatient claims data of all people with statutory health insurance, Germany, 2019

Introduction Evidence of nationwide and regional morbidity of Lyme borreliosis (LB) in Germany is lacking. Aims We calculated the total number of incident LB cases in Germany in 2019, compared regional variations, investigated the extent of possible under-reporting in notification data and examined the association between high incidence areas and land cover composition. Methods We used outpatient claims data comprising information for people with statutory health insurance who visited a physician at least once between 2010 and 2019 in Germany (n = 71,411,504). The ICD-10 code A69.2 was used to identify incident LB patients. Spatial variations of LB were assessed by means of Global and Local Moran’s Index at district level. Notification data were obtained for nine federal states with mandatory notification from the Robert Koch Institute (RKI). Results Of all insured, 128,177 were diagnosed with LB in 2019, corresponding to an incidence of 179 per 100,000 insured. The incidence varied across districts by a factor of 16 (range: 40–646 per 100,000). We identified four spatial clusters with high incidences. These clusters were associated with a significantly larger proportion of forests and agricultural areas than low incidence clusters. In 2019, 12,264 LB cases were reported to the RKI from nine federal states, while 69,623 patients with LB were found in claims data for those states. This difference varied considerably across districts. Conclusions These findings serve as a solid basis for regionally tailored population-based intervention programmes and can support modelling studies assessing the development of LB epidemiology under various climate change scenarios.
Concomitant presentation of eosinophilic or oncocytic mucoepidermoid carcinoma, immunoglobulin G4–related disease, and adult-onset asthma and periocular xanthogranuloma: Case report of 3 uncommon clinical entities

Rationale: Immunoglobulin (Ig) G4–related disease (IgG4-RD) reportedly has a strong relationship with adult-onset asthma and periocular xanthogranuloma (AAPOX) and may be linked to sclerosing mucoepidermoid carcinoma (MEC). We present a rare case of IgG4-RD and AAPOX occurring in a patient with resected eosinophilic or oncocytic MEC. Patient concerns: A 52-year-old woman was referred to our rheumatology clinic in 2020 to be evaluated for suspected IgG4-RD. Diagnoses: The patient had diagnoses of periorbital xanthelasmas, worsening glucocorticoid-dependent chronic rhinosinusitis and adult-onset asthma, and cervical lymphadenopathy persisting 2 years after resection of a low-grade MEC of a minor salivary gland. Interventions: Because the patient’s symptomatic relief was glucocorticoid dependent, IgG4-RD was suspected, and she was referred to our medical center. Her amylase and lipase levels were elevated. Serum IgG4 levels were initially within normal limits, but IgG4-RD was diagnosed because of the presence of lymphadenopathy and evidence of pancreatitis, which was shown on positron emission tomography/computed tomography. Furthermore, the IgG4 levels later increased without explanation. After the patient began combination therapy with a glucocorticoid (prednisone) and methotrexate, her symptoms improved but recurred when the daily oral glucocorticoid dosage decreased below 10 mg. An excisional biopsy of her right submandibular gland in 2021 yielded results consistent with IgG4-RD. In addition, AAPOX was diagnosed, given the presence of periocular edema and plaques, adult-onset asthma, and rhinosinusitis. Outcome: The patient was carcinoma free at last follow-up and was receiving medication to treat the other conditions. Lessons: The diagnosis of these 3 concomitant, uncommon entities required approximately 7 years of medical investigations. Clinicians should know that IgG4-RD, AAPOX, and MEC may occur together.
Gender differences in the experience of burnout and its correlates among Chinese psychiatric nurses during the COVID‐19 pandemic: A large‐sample nationwide survey

Abstract Psychiatric nurses often experience burnout and other mental health symptoms. However, few studies have examined these phenomena and gender‐specific associated factors during the COVID‐19 pandemic. We surveyed a national sample of psychiatric nurses (N = 8971) from 41 tertiary psychiatric hospitals in China as part of a large national survey conducted during the pandemic. The Maslach Burnout Inventory‐Human Service Survey was used to assess burnout and the Depression, Anxiety, and Stress Scale‐21 was used to assess mental health symptoms. Binary logistic regression analyses were used to explore factors associated with burnout in the entire sample and separately by gender. The overall prevalence of burnout was 27.27%, with the rate in male psychiatric nurses (32.24%) being significantly higher than that in female psychiatric nurses (25.97%). Many key demographic factors (such as the male gender and marital status), work‐related variables (such as a mid‐level professional title, having an administrative position, longer working hours, more monthly night shifts, and the perceived negative impact of the COVID‐19 pandemic on medical work) were significantly associated with burnout in the whole sample. Moreover, burnout was associated with depression, anxiety, and stress symptoms in the whole sample. Gender‐specific factors associated with burnout were also identified: burnout was associated with night shifts in male psychiatric nurses, whereas it was associated with single or married marital status, a mid‐level professional title, and having an administrative position among female psychiatric nurses. The high rates of burnout and mental health symptoms in psychiatric nurses need attention from hospital administrators. While mental health symptoms, longer working hours, and the perceived impact of COVID‐19 are associated with burnout in both genders, gender‐specific factors also warrant special attention when developing gender‐specific interventions.
Double-Layer Orthogonal-Offset Platforms in fluid and insolation environments

The DLOOP is a structure of non-overlapping tiles (typically corner connected) occupying two layers. Interest in the DLOOP arises from Photo-Voltaic (PV) tracking applications. The tiles (PV modules) of contemporary tracking systems are within one contiguous layer, i.e. a side-by-side platform (SSP). Trees collect solar energy using branching structures to support leaves which are, similar to PV modules, planar surfaces of solar energy transformation. The tree’s form is naturally excellent for lowering structural stress in limbs and thermal stress in leaves. For analogous reasons, related to the creation of flow paths that would otherwise be blocked, this research hypothesised (and has subsequently shown) that: * the fluid (wind) dynamic force on tiles of high inclination SSP may be reduced (up to 30%) adopting DLOOP arrangements; and * the temperature of heated tiles in SSP may be reduced (up to 5K within nominal and hot terrestrial environments), by passive convective cooling, adopting DLOOP arrangements. Fluid (wind) dynamic force is significant in PV applications because it typically exceeds the force of gravity on the tiles of SSP in 13m/s winds and increases with velocity squared. Hence reducing wind force by 30% should allow 40% more tiles to be fitted to contemporary tracking mechanisms. Temperature is significant in PV applications because the performance of PV tiles typically falls 0.4%/K. Hence a 5K reductiion in temperature should improve efficiency 2%. A combination of wind-tunnel tests, Particle Image Velocimetry and Computational Fluid Dynamic (CFD) simulations using Reynolds Averaged Navier Stokes and Large Eddy Simulation turbulence models was used for the fluid dynamic research.
Errors in Abstract, Results, and Figure

and Results, there was a typographical error in the percentage of Hispanic patients in the prepandemic period. It should have read 17.1%. Additionally, the title of panel A in Figure 1 should have read "Fetal death or stillbirth," and the title of panel B should have read "Maternal death during delivery hospitalization. " This article has been corrected.1. © 2022 American Medical Association. All rights reserved.
Electromagnetic compatibility of PLC adapters for in-home/domestic networks

Abstract The use of programable logic controllers (PLC) technology in electrical networks 230 V causes electromagnetic radiation that interferes with other electrical equipment connected to the network [1–4]. Therefore, this article describes the issues of electromagnetic compatibility (EMC) of new PLC adapters used in IP broadband services in a multi-user environment. The measurements of disturbing electromagnetic field originated in PLC adapters were made in a certified laboratory EMC (laboratory of electromagnetic compatibility) in the Institute of Electrical Engineering at Faculty of Electrical Engineering and Information Technology of the Slovak University of Technology in Bratislava. The measured spectra of the radiated electromagnetic field will be compared with the results obtained when testing older PLC modems [5].
The Effect of Novel Exogenous Ketone Supplements on Blood Beta-Hydroxybutyrate and Glucose

Abstract Exogenous ketone monoesters can raise blood β-OHB and lower glucose without other nutritional modifications or invasive procedures. However, unpleasant taste and potential gastrointestinal discomfort may make adherence to supplementation challenging. Two novel ketone supplements promise an improved consumer experience but differ in their chemical properties; it is currently unknown how these affect blood β-OHB and blood glucose compared to the ketone monoester. In a double-blind randomized cross-over pilot study, N=12 healthy individuals (29 ± 5 years, BMI = 25 ± 4 kg/m2, 42% female) participated in three experimental trials with a different ketone supplement providing 10 grams of active ingredient in each; (i) the monoester (R)-3-hydroxybutyl (R)-3-hydroxybutyrate, (ii) D-β-hydroxybutyric acid with R-1,3-butanediol, and (iii) R-1,3-butanediol. Blood β-OHB and glucose were measured via finger prick capillary blood samples at baseline and across 240 minutes post-supplementation. Supplement acceptability, hunger, and gastrointestinal distress were assessed via questionnaires. β-OHB was elevated compared to baseline in all conditions. Total and incremental area under the curve (p < 0.05) and peak β-OHB (p < 0.001) differed between conditions with highest values seen in the ketone monoester condition. Blood glucose was reduced after consumption of each supplement, with no differences in total and incremental area under the curve across supplements. Supplement acceptability was greatest for D-β-hydroxybutyric acid with R-1,3-butanediol, with no effect on hunger or evidence of gastrointestinal distress across all supplements. All ketone supplements tested raised β-OHB with highest values seen after ketone monoester ingestion. Blood glucose was lowered similarly across the assessed time frame with all three supplements.
Epidemiological profile and effectiveness of immediate postpartum contraception in Brazilian women

We analyzed the epidemiological profile of women who inserted copper intrauterine device (Cu-IUD), subdermal etonogestrel implant (ENG), tubal ligation (TL), depot medroxyprogesterone acetate (DMPA) or did not choose a contraceptive method (NCM) in the immediate postpartum. Also, we compared the contraceptive effectiveness of Cu-IUD and DPMA with non-MAC. Data from 20896 women were collected, of which 8183 (39%) opted for Cu-IUD, 559 (2.5%) DPMA, and 10989 (52.5%) for any method. When comparing these groups, women in the DPMA were younger (26.5+=7.3, p<0.05), and NCM showed women with a lower number of pregnancies (2.2+-1.3, p<0.05). Subjects in the TL group (4,6%) had the higher number of pregnancies (3,8+-1.2, p<0.05), and ENG group, the highest number of miscarriages (1.6+-1.3, p<0.05). Of those women who returned pregnant, 5.5% belonged to the DPMA group, 6% to the NCM group, and 2.3% to the Cu-IUD. Women who opted for Cu-IUD insertion were younger, had more pregnancies and vaginal delivery when compared to those who did not choose a method. Of those women who returned, the minority opted for Cu-IUD compared to those that opted for DPMA or no method.
Exploring structural connectomes in children with unilateral cerebral palsy using graph theory

We explored structural brain connectomes in children with spastic unilateral cerebral palsy (uCP) and its relation to sensory‐motor function using graph theory. In 46 children with uCP (mean age = 10 years 7 months ± 2 years 9 months; Manual Ability Classification System I = 15, II = 16, III = 15) we assessed upper limb somatosensory and motor function. We collected multi‐shell diffusion‐weighted, T1‐weighted and T2‐FLAIR MRI and identified the corticospinal tract (CST) wiring pattern using transcranial magnetic stimulation. Structural connectomes were constructed using Virtual Brain Grafting‐modified FreeSurfer parcellations and multi‐shell multi‐tissue constrained spherical deconvolution‐based anatomically‐constrained tractography. Graph metrics (characteristic path length, global/local efficiency and clustering coefficient) of the whole brain, the ipsilesional/contralesional hemisphere, and the full/ipsilesional/contralesional sensory‐motor network were compared between lesion types (periventricular white matter (PWM) = 28, cortical and deep gray matter (CDGM) = 18) and CST‐wiring patterns (ipsilateral = 14, bilateral = 14, contralateral = 12, unknown = 6) using ANCOVA with age as covariate. Using elastic‐net regularized regression we investigated how graph metrics, lesion volume, lesion type, CST‐wiring pattern and age predicted sensory‐motor function. In both the whole brain and subnetworks, we observed a hyperconnectivity pattern in children with CDGM‐lesions compared with PWM‐lesions, with higher clustering coefficient (p = [<.001–.047], ηp2 =[0.09–0.27]), characteristic path length (p = .003, ηp2 =0.19) and local efficiency (p = [.001–.02], ηp2 =[0.11–0.21]), and a lower global efficiency with age (p = [.01–.04], ηp2 =[0.09–0.15]). No differences were found between CST‐wiring groups. Overall, good predictions of sensory‐motor function were obtained with elastic‐net regression (R2 = .40–.87). CST‐wiring pattern was the strongest predictor for motor function. For somatosensory function, all independent variables contributed equally to the model. In conclusion, we demonstrated the potential of structural connectomics in understanding disease severity and brain development in children with uCP.
Psychiatric map diagnosis in mental disorders

The misdiagnosis between schizophrenia (SCZ) and bipolar disorder (BPD) has been a challenge in psychiatry. It is also a long-time unsolved mislabeled learning problem in machine learning and AI fields. In this study, we propose a psychiatric map (pMAP) diagnosis, which is built upon a novel feature self-organizing map (fSOM) algorithm, to tackle it. The psychiatric map summarizes the latent essential characteristics of each observation on a two-dimensional fSOM plane. It solves the misdiagnosis problem by providing high-accuracy psychiatric detection via automatically mislabeled observation identification. Furthermore, pMAP provides powerful and informative visualization for each observation in unveiling hidden psychiatric subtype discovery. This study also presents new insight into the pathology of psychiatric disorders by constructing the devolution path of psychiatric states via relative entropy analysis that discloses latent internal transfer and devolution road maps between different subtypes of the control, BPD, and SCZ groups. To the best of our knowledge, it is the first study to solve mislabel learning for high-dimensional data in machine learning and will inspire more future work in this field.
Uses and practices of digital services in a situation of mobility: evolution versus revolution? The case of the Champs Elysées

ABSTRACT The ongoing digital revolution is transforming economic production systems as well as our daily lives. If the expectancies in terms of innovation and opportunities are very high on the supply side, little is known about the effective uses of digital tools by customers and the impact on them and their consumption patterns, especially in a situation of mobility. Tourism for example has been tremendously impacted by the digital transformation. It has changed the way people plan, book and travel, but also the way the stakeholders communicate on their destination. But it is also expected that mobile and wireless technologies change the tourist experience of the destination. Mobile devices could induce change in tourist behaviour at the last minute in situ. By using an analysis in terms of services, we suggest that suppliers and tourists in territories coproduce M-tourism services. These services depend on the tourist behaviour but also on the supply, which is available in the destination. Drawing on a survey conducted on the Champs Elysées in Paris in 2018, this paper analyses how different types of people (tourists, residents, workers, etc.) are using these digital services.