Miracle-dz/UniFAR-FTUs huggingface dataset:
Insights into the phylogeny of the ciliate of class Colpodea based on multigene data

Abstract In the class Colpodea, there are many unresolved evolutionary relationships among taxa. Here, we report 30 new sequences including SSU‐rRNA, ITS1‐5.8S‐ ITS2 rRNA, and the mitochondrial small subunit ribosomal RNA (mtSSU‐rRNA) genes of five colpodeans, and conduct phylogenetic analyses based on each individual gene and a two‐gene concatenated dataset. For the first time, multi‐genes were used to analyze phylogenetic relationships in the class Colpodea. The main findings are: (1) SSU‐rRNA, ITS1‐5.8S‐ ITS2 rRNA, and mtSSU‐rRNA gene sequences of C. reniformis and C. grandis are provided for the first time, and these two species group into the clade including C. inflata, C. lucida, C. cucullus, and C. henneguyi; (2) clustering pattern and morphological similarity indicate that Bresslauides discoideus has a close relation with Colpodidae spp. ; (3) Emarginatophrya genus diagnosis is improved to be ‘Hausmanniellidae with sharply shortened and isometric leftmost 1‐4 ciliary rows’ and Colpoda elliotti is transferred to Emarginatophrya; (4) the genus Colpoda is still non‐monophyletic with the addition of 10 populations from five Colpoda species sequences, but there are only two Colpoda groups left based on the present work: Group I comprises C. inflata, C. lucida, C. cucullus, C. henneguyi, C. reniformis, and C. grandis, Group II comprises C. maupasi and C. ecaudata, and the presence of diagonal grooves and the way the vestibular opens might be the two key features that differentiates Colpoda species groups; (5) a close molecular relationship, and highly similar merotelokinetal mode, somatic ciliary pattern, and basic organization of the oral apparatus with P. steinii suggests Bromeliothrix metopoides should be temporarily assigned to Colpodidae.
Human Herpesvirus 8 in Australia: DNAemia and Cumulative Exposure in Blood Donors

Human herpesvirus 8 (HHV-8), the causative agent of Kaposi’s sarcoma, multicentric Castleman’s disease and primary effusion lymphoma, predominantly manifests in immunocompromised individuals. However, infection in immunocompetent individuals does occur. The prevalence of HHV-8 exposure in blood donors from non-endemic countries ranges between 1.2% and 7.3%. Nothing was known about the prevalence in Australian blood donors. Therefore, this study investigated the active and cumulative exposure of HHV-8 in this cohort. Plasma samples (n = 480) were collected from eastern Australian blood donors and were tested for HHV-8 DNA by qPCR, and for HHV-8 antibodies by two different ELISAs. Samples initially positive on either ELISA were retested in duplicate on both, and on a mock-coated ELISA. Any samples positive two or three out of the three times tested on at least one ELISA, and repeat negative on the mock-coated ELISA, were assigned as repeat positive. None of the 480 samples tested contained HHV-8 DNA. Serological testing revealed 28 samples (5.83%; 95% CI: 3.74–7.93%) had antibodies to HHV-8. There was no difference (p > 0.05) in seropositivity between sex or with increasing age. This is the first study to show serological evidence of cumulative HHV-8 exposure and no HHV-8 DNAemia within a select blood donor population in Australia. Our molecular and serological data is consistent with published results for blood donors residing in HHV-8 non-endemic countries, which shows the prevalence to be very low.
Observer‐based consensus tracking control for a class of nonstrict‐feedback nonlinear multi‐agent systems with prescribed performance and input quantization

This article investigates the consensus tracking problem with predefined transient and steady performance requirements for a class of nonstrict‐feedback nonlinear multi‐agent systems (MASs) with input quantization under a directed graph. Based on prescribed performance error transformation methods and command filtered backstepping techniques, a novel observer‐based adaptive control protocol is proposed, where neural observers are designed to estimate unmeasurable states and radial basis function neural networks are constructed to compensate command filter errors. The proposed protocol can be applied to a more general class of nonlinear MASs with nonstrict‐feedback nonlinear dynamics and unmeasurable states information. It is strictly proved that all signals in the whole MAS are semi‐globally uniformly ultimately bounded and both the transient and steady performances of the consensus tracking errors satisfy prescribed performance requirements. Finally, three numerical examples are presented to validate the effectiveness of the proposed protocol.
Research Status of Robot Grab Detection Based on Vision

With the progress of science and technology and the continuous improvement of living standards, robots are more and more widely used in life and production, and robot grasping technology is also constantly improving. In practical application, accurate grasp detection of target objects is an important part of robot grasping task. In this paper, the parallel two-fingered gripper is used as the end of the robot arm's grasping, and the research status of grasping detection, which is the key part in the grasping process of the robot arm based on vision, is summarized. The 2D planar grasping and 6-DOF spatial grasping are compared and analyzed in detail. At the same time, it also summarizes the commonly used evaluation indexes of capturing data sets and capturing detection, and points out the challenges faced by vision-based robot capturing and the future direction of solving these challenges.
Integrin α6 Indicates a Poor Prognosis of Craniopharyngioma through Bioinformatic Analysis and Experimental Validation

Background Craniopharyngioma (CP) is a benign slow-growing tumor. It tends to affect children, and the number of patients is on rise. Considering the high morbidity and mortality of CP, it is urgent and pivotal to identify new biomarkers to uncover the etiology and pathogenesis of CP. Methods The “limma” package was utilized to calculate the data from the Gene Expression Omnibus (GEO) database. Based on differentially expressed genes (DEGs), gene ontology and pathway analysis were deduced from the DAVID web tool. Further, we constructed a protein-protein interaction (PPI) network. Weighted correlation network analysis (WGCNA) was utilized to build a coexpression network. Finally, Western blotting and survival analysis were performed to examine the expression level of important metabolism-related genes. Results Three hundred and eighty-four DEGs were identified between normal tissues and CPs from the GSE94349 and GSE26966 datasets. The Venn diagram for DEGs and hub genes in the ‘turquoise' module revealed four key genes. Finally, the outcome of the survival analysis suggested that Integrin α6 (ITGA6) significantly affected the overall survival time of the patients with CP. Conclusion IGTA6, as a metabolism-related molecule, was found to be substantially related to the overall survival of patients with CP.
Ad typicality judgments in the processing of creative television ads

Abstract The purpose of this research is to better understand the role judgments of ad typicality—the representativeness of an ad for a product category—play in the processing of television advertising. Such judgments would include the expected themes and feelings to be experienced from viewing ads of a product category. This is a vital undertaking because consumers’ judgments of typicality are used in judgments of originality (divergence)—a key dimension of creative ads. However, the nature of ad typicality judgments remains mostly unexplained. Specifically, researchers have not offered rich explanations regarding the antecedents of ad-typicality judgments, or the complex effects of ad-typicality judgments regarding attitude toward the ad. This study addresses these issues and offers new understanding for such phenomena related to ad typicality.
Topographic factor of water erosion – analysis of watershed morphometry and RUSLE LS factor in GIS environment

Soil erosion is the most serious soil degradation factor on the territory of Bulgaria. Nearly 66 % of its area have slopes in a range greater than 3°. The predominant hilly-mountainous relief and high slope degrees are prerequisites for development of water erosion. The properties of the topographic surface as a conditioning factor of erosion processes are evaluated in the current study on the example of the Dzhebelska River watershed (Southern Bulgaria). The following morphometric parameters are considered: basin relief, Melton index, slope and stream power index (SPI). Slope length and steepness factor (LS factor) is calculated using the slope degree and specific contributing area. The values vary between 0 and 43.36. The results of the analysis of the morphometric parameters indicate high erosion susceptibility in the upper and the middle part of the watershed but active erosion can be observed too in the low part of the watershed, where first order streams (Strahler’s method) flows directly to the river of fifth order. The current study is done in GIS environment on the base of 12 m digital elevation model.
Exemplifying Inclusive Excellence: How Indiana University Purdue University Indianapolis Leads by Example in Kinesiology

This article documents the highlights achieved by the Department of Kinesiology at Indiana University Purdue University Indianapolis over the span of 25 years that culminated with their being awarded the Inclusive Excellence award as sponsored by the American Kinesiology Association. Furthermore, this journey was presented using the special issue focus on leadership. Presented experiences occurred within the typical faculty understanding of teaching, research, and service. Recognition was given to the university and campus that hosts this department as it related to the overall diversity and inclusion culture developed on the broader scale, as this is important to acknowledge. This journey could inform or inspire other similar units as they strive to enhance diversity and inclusive excellence in their respective institutions.
WEAK GALACTIC HALO–DWARF SPHEROIDAL CONNECTION FROM RR LYRAE STARS

We discuss the role that dwarf galaxies may have played in the formation of the Galactic halo (Halo) using RR Lyrae stars (RRL) as tracers of their ancient stellar component. The comparison is performed using two observables (periods, luminosity amplitudes) that are reddening and distance independent. Fundamental mode RRL in 6 dwarf spheroidals (dSphs) and 11 ultra faint dwarf galaxies (∼1300) show a Gaussian period distribution well peaked around a mean period of 〈Pab〉 = 0.610 ± 0.001 days (σ = 0.03). The Halo RRL (∼15,000) are characterized by a broader period distribution. The fundamental mode RRL in all the dSphs apart from Sagittarius are completely lacking in High Amplitude Short Period (HASP) variables, defined as those having P ≲ 0.48 days and AV ⩾ 0.75 mag. Such variables are not uncommon in the Halo and among the globular clusters and massive dwarf irregulars. To further interpret this evidence, we considered 18 globulars covering a broad range in metallicity (−2.3 ≲ [Fe/H] ≲ −1.1) and hosting more than 35 RRL each. The metallicity turns out to be the main parameter, since only globulars more metal-rich than [Fe/H] ∼ −1.5 host RRL in the HASP region. This finding suggests that dSphs similar to the surviving ones do not appear to be the major building-blocks of the Halo. Leading physical arguments suggest an extreme upper limit of ∼50% to their contribution. On the other hand, massive dwarfs hosting an old population with a broad metallicity distribution (Large Magellanic Cloud, Sagittarius) may have played a primary role in the formation of the Halo.
The Optimal Sine Pulse Frequency of Pulse Hydraulic Fracturing for Reservoir Stimulation

Pulse hydraulic fracturing (PHF) is a key technique for reservoir stimulation. PHF can well accelerate the rupture of rock. However, the supercharging mechanism of PHF is not fully understood. The main reason is that the pressure distribution and its variation, especially the peak pressure characteristics, are unclear inside the pipe and fissure. The present research focuses on the sine pulse applied at the inlet of a pipe or fracture to reveal the variation regularity of peak pressure with the pulse frequency, amplitude, pipe length, diameter and wave speed. First, the weakly compressible Navier–Stokes equations were developed to simulate the variation of fluid pressure. The computation codes were developed using the MacCormack method validated by the existing experimental data. Then, the sine pulse effect was studied inside the pipe and fissure. Last, a new frequency model was built to describe the relationship between the optimal pulse frequency, wave speed and pipe length. The results show that there is a family of frequencies at which the peak pressure of the endpoint can be significantly enhanced and that these frequencies are the optimal pulse frequency. It is found that the optimal pulse frequency depends on the pipe or fissure length and wave speed. At the optimal pulse frequency, the peak pressure at the endpoint can be increased by 100% or more, and the cavitation phenomenon occurs. However, the peak pressure decreases when with the decrease in the pipe diameter and fissure departure due to the friction drag effect of the wall. These new landmark findings are very important for the PHF technique. In addition, a new universal frequency model is built to predict the optimal sine pulse frequency. The present research shows the variation regularity of the fluid pressure inside the pipe and develops a sine frequency-controlled method, providing a potential guide for reservoir stimulation.
Romanian Danube River Hydrocarbon Pollution in 2011–2021

This review paper aims to analyze studies conducted over recent years (2011–2021) on hydrocarbon pollution in the Danube’s Romanian sector. This involves looking at three main issues: Space-related Romanian Danube hydrocarbon pollution; the nature of samples and the types of tests used for hydrocarbon authentication; hydrocarbon effects on bioindicators and fish cell lines. The papers extracted for this review were selected from three scientific article platforms: Web of Science, Science Direct, and Google Scholar, by using keywords, a specific search protocol and various selection filters. The main results of the present analysis are the following: the highest levels of hydrocarbon contamination in suspended particulate matter and sediments were found in the sector Iron Gates-Călărași (2013), and the main pollution sources were industry, navigation and wastewater discharges; sediment and biological samples accumulate higher concentrations of hydrocarbons than water samples, and are a good indicator for these pollutants’ presence; the most widely used bioindicators are aquatic worms, mollusks, crustaceans, the wild common bleak, and, in the laboratory, fish cells; various methods are used in order to confirm hydrocarbon presence and/or their effects on biota: fluorescence, comet assay technique, micronucleus test, complementary passive samplers, in vitro bioassays, fugacity-based calculation model, sensors, oil spill modeling.
The Mixture of Ferulic Acid and P-Coumaric Acid Suppresses Colorectal Cancer through lncRNA 495810/PKM2 Mediated Aerobic Glycolysis

Polyphenol-rich foods are gaining popularity due to their potential beneficial effects in the prevention and treatment of cancer. Foxtail millet is one of the important functional foods, riches in a variety of biologically active substance. Our previous study showed that ferulic acid (FA) and p-coumaric acid (p-CA) are the main anticancer components of foxtail millet bran, and the two have a significant synergistic effect. In the present study, the clinical application potential of FA and p-CA (FA + p-CA) were evaluated in vivo and in vitro. The FA and p-CA target gene enrichment analysis discovered that FA + p-CA were associated with aerobic glycolysis. It was further shown that FA + p-CA remodel aerobic glycolysis by inhibiting the glycolysis-associated lncRNA 495810 and the glycolytic rate-limiting enzyme M2 type pyruvate kinase (PKM2). Moreover, PKM2 expression was positively correlated with lncRNA 495810. More interestingly, the exogenous expression of lncRNA 495810 eliminated the inhibitory effects of FA + p-CA on aerobic glycolysis. Collectively, FA + p-CA obstruct the aerobic glycolysis of colorectal cancer cells via the lncRNA 495810/PKM2 axis, which provides a nutrition intervention and treatment candidate for colorectal cancer.
Competitive accretion in the protocluster G10.6-0.4?

We present the results of high spatial resolution observations in the 1.1-mm waveband with the Submillimetre Array (SMA) towards the protocluster G10.6−0.4. The 1.1-mm continuum emission reveals seven dense cores. Redshifted absorption dips are seen in the HCN (3–2) lines in these cores, suggesting infalling of gas towards the dense cores. This is the first time that infall has been seen towards multiple sources in a protocluster. We also identified four infrared point sources in this region, which are most likely Class 0/I protostars. Two jet-like structures are also identified fromSpitzer/Infrared Array Camera (IRAC) images. The dense core located in the centre has a much larger mass than the off-centre cores. The clump is in overall collapse and the infall motion is supersonic. The standard deviations of core velocities and the velocity differences between the cores and the cloud/clump are all larger than the thermal velocity dispersion. The picture of G10.6−0.4 seems to favour the ‘competitive accretion’ model, but this needs to be tested through further observations.
Nonlinear power spectrum from resummed perturbation theory: a leap beyond the BAO scale

A new computational scheme for the nonlinear cosmological matter power spectrum (PS) is presented. Our method is based on evolution equations in time, which can be cast in a form extremely convenient for fast numerical evaluations. A nonlinear PS is obtained in a time comparable to that needed for a simple 1-loop computation, and the numerical implementation is very simple. Our results agree with N-body simulations at the percent level in the BAO range of scales, and at the few-percent level up to k 1 h/Mpc at z0.5, thereby opening the possibility of applying this tool to scales interesting for weak lensing. We clarify the approximations inherent to this approach as well as its relations to previous ones, such as the Time Renormalization Group, and the multi-point propagator expansion. We discuss possible lines of improvements of the method and its intrinsic limitations by multi streaming at small scales and low redshifts.
Incompressible fluid flows in rapidly rotating cavities

The subject of incompressible fluid flows in rapidly rotating cavities, relevant to the dynamics of the Earth’s outer core, is addressed here by means of numerical modeling. We recall in the introduction what makes this topic fascinating and challenging, and emphasize the need for new, more flexible numerical approaches in line with the evolution of today’s parallel computers. Relying upon recent advances in numerical analysis, we first introduce in chapter 2 a spectral element model of the axisymmetric Navier-Stokes equation, in a rotating reference frame. Comparisons with analytical or published numerical solutions are made for various test problems, which highlight the spectral convergence properties and adaptivity of the approach. In chapter 3, we couple this axisymmetric kernel with a Fourier expansion in longitude in order to describe the dynamics of three-dimensional convective flows. Again, several reference problems are studied. In the specific case of a rotating fluid undergoing thermal convection, this so-called Fourier-spectral element method (FSEM) proves to be as accurate as standard pseudo-spectral techniques. Having this numerical tool anchored on solid grounds, we study in chapter 4 fluid flows driven by thermal convection and precession at the same time. A new topic in the vast field of fluid mechanics, convecto-precessing flows are of particular importance for the Earth’s core, and the equations governing their evolution are derived in detail. We solve these using the FSEM; results seem to indicate that to first order, thermal convection and precession ignore each other. We discuss the relevance of these calculations for the Earth’s core and outline directions for future related research.
Consumer Characterization of Wet- and Dry-Aged Mutton Flavor Profile Using Check-All-That-Apply

The aim of this study was to assess if consumers could characterize wet- and dry-aged mutton flavor profiles using CATA (check-all-that-apply). A flavor lexicon was developed for mutton, and consumers assessed wet- and dry-aged mutton patties against this lexicon using CATA methodology. Results indicate that consumers most often associated caramel and roasted flavors with dry-aged patties, and “sheepy” and metallic flavors with wet-aged patties. Volatile analysis supported the consumer characterization as there were more Maillard reaction products, including pyrazines, which are associated with roasted and cooked flavors, found in the dry-aged patty volatile profile. More 1-octen-3-one, which is associated with metallic flavors, was found in the wet-aged patty volatile profile. These results provide validation that the lexicon utilized in this study (i) is suitable for the characterization of mutton flavor and (ii) will have applications for future investigations into the flavor components driving consumer liking for mutton.
Large-density field theory, viscosity and ‘2kF’ singularities from string duals

We analyze systems where an effective large-N expansion arises naturally in gauge theories without a large number of colors: a sufficiently large charge density alone can produce a perturbative string ('tHooft) expansion. One example is simply the well-known NS5/F1 system dual to AdS3 × T4 × S3, here viewed as a 5+1 dimensional theory at finite density. This model is completely stable, and we find that the existing string-theoretic solution of this model yields two interesting results. First, it indicates that the shear viscosity is not corrected by α′ effects in this system. For flow perpendicular to the F1 strings the viscosity to entropy ratio take the usual value 1/4π, but for flow parallel to the F1s it vanishes as T2 at low temperature. Secondly, it encodes singularities in correlation functions coming from low-frequency modes at a finite value of the momentum along the T4 directions. This may provide a strong coupling analogue of finite density condensed matter systems for which fermionic constituents of larger operators contribute so-called ‘2kF’ singularities. In the NS5/F1 example, stretched strings on the gravity side play the role of these composite operators. We explore the analogue for our system of the Luttinger relation between charge density and the volume bounded by these singular surfaces. This model provides a clean example where the string-theoretic UV completion of the gravity dual to a finite density field theory plays a significant and calculable role.