Miracle-dz/UniFAR-FTUs huggingface dataset:
Quality of sleep, fatigue and adherence to antiepileptic medications among patients with epilepsy

Epilepsy is the second most common neurological disorder which affects 70 million individuals worldwide. The study assesses the quality of sleep, fatigue and adherence to antiepileptic medications among patients with epilepsy (PWE). A quantitative descriptive correlation study design was adopted. The investigator used simple random sampling technique to select 100 patients with epilepsy, who fulfilled the inclusion criteria. Quality of sleep was assessed using “Pittsburgh Sleep Quality Index”, fatigue with “Modified Fatigue Impact Scale” and adherence of antiepileptic medications with “Adherence in Chronic Disease Scale” by Self reporting technique. The study revealed that the quality of sleep was poor in 64% of the subjects, while the remaining, 36% had good quality of sleep. Majorities (83%) of the epileptic patients were found to have no fatigue, 12% had mild fatigue and the remaining 5% had moderate fatigue. Majority (81%) of the subjects were adherent to antiepileptic medications, 18% were moderately adherent and only 1% of them were non-adherent. The study depicts a negative correlation r= -0.099 (p= 0.338) between fatigue and adherence to antiepileptic medications which is not significant (p> 0.01) and shows no correlation (r =0 .0295) (p = 0.771) between the quality of sleep and adherence to antiepileptic medications. The study highlights a positive correlation (r= 0.2831(p= 0.004) between fatigue and the quality of sleep, which is significant (p < 09820.01). The study concludes that attention related to sleep in patients with epilepsy has important implication for diagnosis, seizure control and a better quality of life.
Existence of Multiple Solutions for a p-Laplacian System in ℝ N with Sign-changing Weight Functions

Abstract In this paper, we consider the quasi-linear elliptic problem $$-M\left( {{\int }_{{{\mathbb{R}}^{N}}}}{{\left| x \right|}^{-ap}}{{\left| {{\nabla }_{u}} \right|}^{p}}dx \right)\,\text{div}\left( {{\left| x \right|}^{-ap}}{{\left| \nabla u \right|}^{p-2}}\nabla u \right)=\frac{\alpha }{\alpha +\beta }H\left( x \right){{\left| u \right|}^{\alpha -2}}u{{\left| v \right|}^{\beta }}+\text{ }\lambda \text{ }{{\text{h}}_{1}}\left( x \right){{\left| u \right|}^{q-2}}u,$$ $$-M\left( {{\int }_{{{\mathbb{R}}^{N}}}}{{\left| x \right|}^{-ap}}{{\left| \nabla v \right|}^{p}}dx \right)\,\text{div}\left( {{\left| x \right|}^{-ap}}{{\left| \nabla v \right|}^{p-2}}\nabla v \right)=\frac{\beta }{\alpha +\beta }H\left( x \right){{\left| v \right|}^{\beta -2}}v{{\left| u \right|}^{\alpha }}+\mu {{h}_{2}}\left( x \right){{\left| v \right|}^{q-2}}v,$$ $$u\left( x \right)>0,v\left( x \right)>0,x\in {{\mathbb{R}}^{N}},$$ where $\text{ }\lambda \text{ ,}\mu >\text{0,}\text{1}<\text{p}<\text{N,}\text{1}<\text{q}<\text{p}<\text{p}\left( \tau +1 \right)<\alpha +\beta <{{p}^{*}}=\frac{{{N}_{p}}}{N-p},0\le a<\frac{N-p}{p},a\le b0,M\left( s \right)=k+l{{s}^{\tau }},k>0,l,\tau \ge 0$ and the weight $H\left( x \right),\,{{h}_{1}}\left( x \right),\,{{h}_{2}}\left( x \right)$ are continuous functions that change sign in ${{\mathbb{R}}^{N}}$ . We will prove that the problem has at least two positive solutions by using the Nehari manifold and the fibering maps associated with the Euler functional for this problem.
Expressions of the use of slang among millennial youth on social media and its impact of the extension of Indonesia in society

The research was conducted because of the widespread use of slang among the Indonesian population, especially millennial youth. This study also aims to examine millennial youth slang based on its form, source and pattern of formation, purpose and context of use. The research approach used is descriptive qualitative, namely examining language data in the form of the use of slang by millennial youth and interpreting it. Sources of research data are interview results and social media, namely Facebook, Twitter and Instagram, which contain teenage slang. Data collection techniques were documented, observed and recorded, as well as interviews with fifteen young people who used slang in communicating. The data analysis technique in this study is content analysis. The results of the study show that the use of slang by millennial youth originates from regional languages, Indonesian, foreign languages, as well as a combination of Indonesian and foreign languages. The pattern of forming slang from abbreviations, shortening of words, acronyms, reversal of words, spoofed words and shifts in meaning. The expression of the use of slang among millennial youth on social media and its impact on the extension of Indonesian in society makes a big change in the world of language, this is because teenagers are contaminated by foreign languages so this has an impact on the extension of society. Regarding this problem so that ordinary people feel accustomed to and contaminated with the slang that is widely used by millennial youth at this time, this will affect the resilience of the Indonesian national language which is the identity of the country, so that the impact begins to fade the use of good Indonesian and true because it has been contaminated with the influence of foreign languages.
The effect of a salinity gradient on the dissolution of a vertical ice face

We investigate experimentally the effect of stratification on a vertical ice face dissolving into cold salty water. We measure the interface temperature, ablation velocity and turbulent plume velocity over a range of salinity gradients and compare our measurements with results of similar experiments without a salinity gradient (Kerr & McConnochie, J. Fluid Mech., vol. 765, 2015, pp. 211–228; McConnochie & Kerr, J. Fluid Mech., vol. 787, 2016, pp. 237–253). We observe that stratification acts to reduce the ablation velocity, interface temperature, plume velocity and plume acceleration. We define a stratification parameter, $S=N^{2}Q/{\it\Phi}_{o}$ , that describes where stratification will be important, where $N$ is the Brunt–Väisälä frequency, $Q$ is the height-dependent plume volume flux and ${\it\Phi}_{o}$ is the buoyancy flux per unit area without stratification. The relevance of this stratification parameter is supported by our experiments, which deviate from the homogeneous theory at approximately $S=1$ . Finally, we calculate values for the stratification parameter at a number of ice shelves and conclude that ocean stratification will have a significant effect on the dissolution of both the Antarctic and Greenland ice sheets.
Single frequency 1560nm Er:Yb fiber amplifier with 207W output power and 50.5% slope efficiency

High power fiber lasers/amplifiers in the 1550nm spectral region have not scaled as rapidly as Yb-, Tm-, or Ho-doped fibers. This is primarily due to the low gain of the erbium ion. To overcome the low pump absorption, Yb is typically added as a sensitizer. Although this helps the pump absorption, it also creates a problem with parasitic lasing of the Yb ions under strong pumping conditions, which generally limits output power. Other pump schemes have shown high efficiency through resonant pumping of erbium only without the need for Yb as a sensitizer [1-2]. Although this can enable higher power scaling due to a decrease in the thermal loading, resonant pumping methods require long fiber lengths due to pump bleaching, which may limit the power scaling which can be achieved for single frequency output. By using an Er:Yb fiber and pumping in the minima of the Yb pump absorption at 940nm, we have been able to simultaneously generate high power, single frequency output at 1560nm while suppressing the 1-micron ASE and enabling higher efficiency compared to pumping at the absorption peak at 976nm. We have demonstrated single frequency amplification (540Hz linewidth) to 207W average output power with 49.3% optical efficiency (50.5% slope efficiency) in an LMA Er:Yb fiber. We believe this is the highest reported efficiency from a high power 9XXnm pumped Er:Yb-doped fiber amplifier. This is significantly more efficient that the best-reported efficiency for high power Er:Yb doped fibers, which, to-date, has been limited to ~41% slope efficiency [3].
Eruptive Keratoacanthoma in a 59-year-old Female with Chronic Kidney Disease: A Case Report and Review of Treatment Approaches

We present the case of a 59-year-old female with multiple squamous neoplasms, including keratoacanthomas, well-differentiated squamous cell carcinomas, and prurigo nodules. The patient developed dozens of lesions progressively over the course of a few years. Keratoacanthomas can be challenging to distinguish from well-differentiated squamous cell carcinomas; this and the presence of numerous lesions poses a major challenge with diagnosing and managing this condition. The pathogenesis, challenges with diagnosis and management, and treatment regimens for eruptive keratoacanthomas are further discussed.
Fabrication of ECM Mimicking Bioactive Scaffold: A Regenerative Approach for MSC Mediated Applications

Biomaterials are feasible resources that aids to replace damaged structures in our bodies. The most biologically active flora is Aloe vera which has many bioactive compounds that are anti-inflammatory, antimicrobial, and have ECM mimicking protein content which helps in the healing of wounds and also acts as an ECM factor for stem cell homing and differentiation. The Aloe vera containing 10 w/v of gelatin was lyophilized. Scaffolds had sharper morphology, greater hydrophilic properties, and a Young's modulus of 6.28 MPa and 15.9 MPa of higher tensile strength are desirable. In tissue engineering and regenerative medicine, biologically active scaffolds have been producing hopeful outcomes in both restoration and replacement, respectively. The objective of the present investigation is to test the idea that incorporating gelatin to Aloe vera scaffolds might enhance their structure, good biocompatibility, and possibly even bioactivity. The SEM picture of the composite scaffold revealed pore walls. The scaffolds had linked pores with diameters ranging from 93 to 296 μm. Aloe vera and the matrix interact well, according to the FTIR study, which could lead to a reduction in the amount of water-binding sites and a reduction in the material's ability to absorb water. Aloe vera with 10% gelatin (AV/G) scaffold was investigated for different biological reactions of human gingival tissue mesenchymal stem cells (MSCs) in terms of cell proliferation, morphology, and cell migration. The results demonstrated the potential of the AV/G scaffold as a biomaterial that offers new insight in the field of tissue engineering.
A systematic review and meta-analysis of the measurement properties of concerns-about-falling instruments in older people and people at increased risk of falls

Abstract Background The 16-item Falls Efficacy Scale International (FES-I) is widely used to assess concerns-about-falling. Variants include 7-item Short FES-I, 30-item Iconographical Falls Efficacy Scale (Icon FES) and 10-item short Icon FES. No comprehensive systematic review and meta-analysis has been conducted to synthesise evidence regarding the measurement properties of these tools. Objectives To conduct a systematic review and meta-analysis of the measurement properties of four FES-I variants. Methods MEDLINE, Embase, CINAHL Plus, PsycINFO and Web of Science were searched systematically and articles were assessed for eligibility independently. The methodological quality of eligible studies was assessed using COnsensus-based Standards for the selection of health Measurement INstruments (COSMIN) Risk of Bias checklist. The quality of measurement properties was assessed using COSMIN criteria for good measurement properties. Where possible, meta-analysis was conducted; otherwise, narrative synthesis was performed. Overall certainty of evidence was rated using a modified Grading of Recommendations, Assessment, Development and Evaluation system approach. Results The review included 58 studies investigating measurement properties of the four instruments. There was high-quality evidence to support internal consistency, reliability and construct validity of all instruments. Moderate- to high-certainty evidence suggests one-factor structure of FES-I with two underlying dimensions, one-factor structure of Short FES-I and two-factor structure of Icon FES. There was high-certainty evidence to support the responsiveness of FES-I, with further research needed for the other instruments. Conclusion There is evidence for excellent measurement properties of all four instruments. We recommend the use of these tools with healthy older people and people at a greater risk of falls due to conditions that might affect mobility and balance.
“I’m Fighting for My Life”: Exploring Interactions Between Black Women with Breast Cancer and Healthcare Providers

Black Americans face a multitude of problems in the healthcare system, including challenges during interactions with healthcare providers. The present study examined the quality of healthcare provider–Black patient interactions in a sample of Black American women with a breast cancer diagnosis. More specifically, the study examined potential contributors to Black Americans’ current healthcare experiences and lack of trust by identifying their specific negative and positive encounters in the healthcare system. Three in-person Gatherings (i.e., culturally curated focus groups; N = 37) were conducted as part of a community–academic research partnership, Project SOAR (Speaking Our African American Realities). Four themes were identified through reflexive thematic analysis: Individual and Systemic Injustice Directed at Black Breast Cancer Survivors; Protecting Myself from an Untrustworthy Medical System; Stereotypes Interfered with My Care; and Good Care Should Include Compassion, Respect, Shared Decision Making, and Tailored Support. The present findings highlight the importance of addressing systemic and individual injustice toward Black Americans in healthcare settings generally, and Black women diagnosed with breast cancer specifically.
Improvement of the crystal rotation method to measure the flexoelectric difference (e1–e3) in achiral materials using AC electric fields

ABSTRACT We show that the crystal rotation method for measuring the difference between splay and bend flexoelectric coefficients (e1–e3) [Outram and Elston, Liq. Cryst. 39, 149 (2012)] can be improved by using AC instead of DC fields. The field frequency is small (~0.05 Hz), yet sufficient to get rid of the difficulties connected with the migration of charge carriers. The method is sensitive enough so as to use fields with amplitudes as small as 1 V/mm. This has the advantage of avoiding the consideration of the interaction due to the dielectric anisotropy, and greatly simplifies the analysis of data. The results are extracted from a simple fitting scheme, which involves two parameters. In particular (e1–e3) is obtained from a scale factor in a one-parameter fit. Measurements of the temperature dependence of (e1–e3) are presented for two classical nematic materials. Graphical Abstract
Role of the internet of medical things in care for patients with interstitial lung disease

Purpose of review Online technologies play an increasing role in facilitating care for patients with interstitial lung disease (ILD). In this review, we will give an overview of different applications of the internet of medical things (IoMT) for patients with ILD. Recent findings Various applications of the IoMT, including teleconsultations, virtual MDTs, digital information, and online peer support, are now used in daily care of patients with ILD. Several studies showed that other IoMT applications, such as online home monitoring and telerehabilitation, seem feasible and reliable, but widespread implementation in clinical practice is lacking. The use of artificial intelligence algorithms and online data clouds in ILD is still in its infancy, but has the potential to improve remote, outpatient clinic, and in-hospital care processes. Further studies in large real-world cohorts to confirm and clinically validate results from previous studies are needed. Summary We believe that in the near future innovative technologies, facilitated by the IoMT, will further enhance individually targeted treatment for patients with ILD by interlinking and combining data from various sources.
Educational Intervention for Family Nursing Students in Long-Term Cancer Survivorship: A Randomized Pilot Trial

A randomized pilot study was conducted involving 69 third-year nursing students (ClinicalTrials.gov ID: NCT05270252). Students were randomly assigned to the CG (n = 34) or the intervention group (n = 35), using computer-generated randomization. The CG completed the third-year nursing, and the intervention group received in addition the Learning & Care educational intervention. The aim of this study was to determine the effectiveness, feasibility, and acceptability of the Learning & Care for students to acquire the knowledge, skills, and attitudes necessary to care for survivors and their families. The intervention group significantly improved in knowledge (p = .004; −1.15, 95% confidence interval [CI] [−1.94, −0.37]), skills (p ≤ .0001; −13.51, 95% CI [−15.19, −11.83]), and attitudes (p = .006; −5.61, 95% CI [−8.81, −2.42]). The students' satisfaction was found to be high (93.75%). Offering a family nursing approach improves students' competence to care for long-term cancer survivors and their families.
Epidemiological Characteristics of School Playground Injuries

Reports of children’s play-related injuries have remained stagnant according to epidemiology studies of the past 3 decades. This article provides a unique look into the context of playground injuries within an entire school district, demonstrating the prevalence of these injuries. This study reports that playgrounds are the leading location of school injury, comprising one-third of all elementary school injuries. This study found that while head/neck injuries were the most commonly injured body region within the playground environment, the proportion of head/neck injuries decreased with age, whereas the proportion of extremity injuries increased with age. At least 1 upper extremity injury required outside medical attention for every 4 that were treated on-site, making upper extremity injuries roughly twice as likely to require outside medical attention as injuries to other body regions. The data in this study are useful for interpreting injury patterns in the context and evaluation of existing safety standards for playgrounds.
Rod‐cone dystrophy in an adult with GNB1‐related disorder: An expansion of the phenotype and natural history

GNB1‐related disorder is characterized by intellectual disability, abnormal tone, and other variable neurologic and systemic features. GNB1 encodes the β1 subunit of the heterotrimeric G‐protein, a complex with a key role in signal transduction. Consistent with its particularly high expression in rod photoreceptors, Gβ1 forms a subunit of retinal transducin (Gαtβ1γ1), which mediates phototransduction. In mice, GNB1 haploinsufficiency has been associated with retinal dystrophy. In humans, however, although vision and eye movement abnormalities are common in individuals with GNB1‐related disorder, rod‐cone dystrophy is not yet an established feature of this condition. We expand the phenotype of GNB1‐related disorder with the first confirmed report of rod‐cone dystrophy in an affected individual, and contribute to a further understanding of the natural history of this condition in a mildly affected 45‐year‐old adult.
Changes in axonal and clinical function during intravenous and subcutaneous immunoglobulin therapy in chronic inflammatory demyelinating polyneuropathy

Intravenous immunoglobulin (IVIg) has a rapid clinical effect which cannot be explained by remyelination during each treatment cycle in patients with chronic inflammatory demyelinating polyneuropathy (CIDP). This study aimed to investigate axonal membrane properties during the IVIg treatment cycle and their potential correlation with clinically relevant functional measurements.
The Relationship of Food Insecurity to Nutritional Risk in Independent Living Older Adults

Abstract Understanding the factors that augment optimal health during aging is critical as the US older adult population is increasing. Most research about food insecurity, nutritional risk, and perceived health among older adults are in urban areas or congregate living facilities. Thus, the purpose of this project was to study the relationships among these factors, plus activities of daily living, in community-dwelling older adults in a medium-sized city. Using a qualitative-quantitative study design, a cross-sectional survey was completed by 167 low-income senior apartment residents. Food insecurity in this group was higher than the national and state rate, yet nutrition assistance programs were underutilized and participants under 75 years were more food insecure than their older counterparts. Food insecure residents were at greater nutritional risk, had poorer self-reported health status, were more likely to be depressed, and had a less independent function, including limitations on the ability to shop for and prepare food. The study area is desirable to retirees due to lower cost of living; however, access to services, such as grocery stores, public transportation, and health care providers is limited. This research indicates the need for increased outreach, nutrition assistance, and support services to ensure healthy aging in these regions.
TMJ degenerative joint disease: relationships between CBCT findings, clinical symptoms, and signs

Abstract Objectives The relationships between cone-beam computed tomography (CBCT) findings, Temporomandibular disorder (TMD) symptoms, and signs were investigated in patients with TMJ degenerative joint disease (DJD). Material and Methods Adult patients with Diagnostic Criteria for TMDs (DC/TMD)-defined intra-articular conditions were enrolled and subjected to CBCT assessment. The participants were organized into three groups, namely no (NT), early (ET), and late (LT) TMJ DJD based on radiographic findings. TMD symptoms/signs were appraised using the DC/TMD methodology. Statistical analyses were performed using Chi-square/non-parametric tests and Kappa statistics (α = 0.05). Results The mean age of the participants (n = 877) was 30.60 ± 11.50 years (86.6% women). NT, ET, and LT were observed in 39.7%, 17.0%, and 43.3% of the study sample. Significant differences in the prevalence of TMD symptoms (TMD pain, TMJ sounds, opening, and closing difficulty) and signs (TMD/TMJ pain, TMJ clicking/crepitus, and opening limitation) were discerned among the three groups (p ≤ .001). TMD/TMJ pain and opening difficulty/limitation were more prevalent in early rather than late degenerative changes. While moderate agreements between symptoms and signs were observed for TMD pain/opening limitation, the concurrence for TMJ sounds was fair. Conclusions Young adults with TMJ sounds and pain should be examined with CBCT to establish the extent/progress of osseous changes.