Miracle-dz/UniFAR-FTUs huggingface dataset:
Perceived Benefits and Risk of NSAIDs in Relation to Its Association with Cancer: A Comprehensive Review

Non-steroidal anti-inflammatory drugs (NSAIDs) are often used to treat fever and pain. Apart from its medicinal benefits, it is also well known for its numerous side effects, including myocardial infarction, gastrointestinal haemorrhage, renal failure, etc. Even beside these side effects NSAIDs are believed to play a major role in cancer. Though there are contrary of being inducing or preventive reason for cancer. Many studies shows NSAIDs are associated with the increasing risk of cancer. While as in various studies these drugs also have been investigated for their anti-cancer property as chronic inﬂammation has direct association with carcinogenesis. This review enlights the role of NSAIDs in cancer promotion and cancer prevention, connection between chronic inflammation and cancer, and some of the potentially lethal side effects of these drugs.
Power Decreases Loneliness through Enhanced Social Support: The Moderating Role of Social Exclusion

En los últimos años, el poder y la soledad son dos temas importantes de investigación en psicología social. Sin embargo, están en ramas separadas de literatura a pesar de la relación potencial. Para llenar este vacío, esta investigación investiga sistemáticamente cómo, por qué y cuándo el sentido de poder afecta la soledad examinando el efecto principal, el papel mediador del apoyo social percibido y el papel moderador de la exclusión social. En el Estudio 1, 539 participantes en China participaron en un estudio de encuesta, que incluyó la Escala de Sentido de Poder, la Escala de Apoyo Social Percibido y la Escala de Soledad de UCLA. En el Estudio 2, probamos casualmente los efectos principales y moderadores en un experimento controlado utilizando una muestra de los Estados Unidos. Tomados en conjunto, los resultados muestran que: (1) El sentido de poder reduce la soledad. (2) El apoyo social percibido media esta relación, de modo que el poder fortalece el apoyo social percibido y, por lo tanto, disminuye la soledad. (3) La exclusión social modera esta relación, de modo que la función de amortiguamiento del poder es efectiva sólo cuando la exclusión social está ausente. In recent years, power and loneliness are two important research topics in social psychology. However, they are in separate streams of literature despite the potential relationship. To fill this gap, this research systematically investigates how, why, and when sense of power affects loneliness by examining the main effect, the mediating role of perceived social support, and the moderating role of social exclusion. In Study 1, 539 participants in China participated in a survey study, which included Sense of Power Scale, Perceived Social Support Scale, and UCLA Loneliness Scale. In Study 2, we casually tested the main and moderating effects in a controlled experiment using a sample from the United States. Taken together, the results show that: (1) Sense of power reduces loneliness. (2) Perceived social support mediates this relationship, such that power enhances perceived social support and thereby decreases loneliness. (3) Social exclusion moderates this relationship, such that the buffering function of power is effective only when social exclusion is absent.
Mobile Phone Influence on Sexual Behaviour of Undergraduate Students: A Case Study of Jomo Kenyatta University of Agriculture and Technology, Kenya

Purpose: The study sought to examine the influence of mobile phone use on sexual behaviour of university students: a case study of Jomo Kenyatta University of Agriculture and Technology, Kenya. The study specifically, sought to examine the effect of characteristics of mobile phones users, uses and gratification of mobile phones and the frequency of using mobile phones on sexual behaviour of university students in Jomo Kenyatta University of Agriculture and Technology, Kenya. Methodology: The research design that was adopted was descriptive in nature. The study also used both quantitative and qualitative data obtained from the respondents using questionnaires and Focus Group Discussions (FGDs) guides. Quantitative data was collected using questionnaires while qualitative data was collected using Focus Group Discussions. The study adopted a stratified random sampling technique to select the sample size from the three strata, which are the various Faculties in JKUAT. The study then used Fisher’s formula to arrive at an adequate scientific sample size of 384 students who were targeted using convenient sampling, that is those that are ready to respond to the questionnaires and the Focus Group Discussions (FGDs). The quantitative data in this research was analyzed using descriptive statistics and inferential statistics using SPSS v22.0. Results: It was concluded that male students are more likely to use protection consistently compared to female students. In addition, the findings imply that consistency in condom use is a factor that is dependent on the age of the individual. In addition, relationship status is a contributor to the behaviour of the students sexually. For those that are in serious relationships, their use of protection declines due to the build-up of emotional and intimate trust towards each other. The findings likewise indicate that the student’s usage of mobile phones correlates significantly with the consistent use of protection for safe sex. Those students who have had their phones since they joined Campus are more likely to practice safe sex. In addition, heavy users of mobile phones are likely to practice safe sex including those who browse the internet for news updates. Unique contribution to theory, policy and practice: The study recommends the media practitioners need to step up the production of morally acceptable media content and offer a platform for advertising and campaigning for sexual conduct by encouraging and stressing the use of protection. The Ministry of Health and Ministry of Education should actively involve the undergraduate students in reproductive information awareness campaigns for ensuring positive attitudes towards responsible sexual behaviour and promoting best sexual practices.
Clinical Success and Safety of Percutaneous Transhepatic Biliary Drainage for Biliary Obstruction after Deceased Donor Liver Transplantation

Introduction: Endoscopic Retrograde Cholangiopancreatography (ERCP), EUS-guided Biliary Drainage (EUS-BD) or Double Balloon enteroscopy assisted-ERCP (DB-ERCP) are commonly used to manage biliary complications after Liver Transplant (LT). Percutaneous Transhepatic Biliary Drainage (PTBD) remains second-line treatment in patients after LT; however it has not been well studied, particularly in Deceased Donor Liver Transplantation (DDLT). We aimed to determine the efficacy and safety of PTBD in this setting. Methods: This is a retrospective study of patients who underwent PTBD for biliary obstruction post DDLT at a quaternary referral centre between1st of January 2003 and 1st of September 2019. Technical success was defined as successful biliary cannulation and treatment. Clinical success was defined as a 50% reduction in serum bilirubin 7 days post-procedure and/or a 75% reduction at 4 weeks. Results: 58 LT patients underwent 232 PTBDs (83% male, median age 55 [IQR 47 to 58] years). The most common underlying liver diseases were Primary Sclerosing Cholangitis (PSC) 16 (28%) and hepatitis C 15 (26%). Thirty (52%) patients had hilar and intra-hepatic strictures, 18 (31%) had surgical bilio-enteric anastomotic strictures and 10 (17%) patients had duct-to-duct anastomotic strictures. Clinical success was achieved in 27 (47%) patients and technical success in 53 (91%) patients. Complications occurred in 32 (55%) patients. Seven (12%) patients died within 90 days of PTBD. Conclusion: Although technical success for PTBD post LT is high, clinical success is modest at 47% with complications occurring in the majority of patients. PTBD carries a significant risk of adverse events in this complex patient population.
Head Teachers’ Instructional Supervisory Practices and Teachers’ Motivation in Teaching

The study determined the relationship between Government Secondary school head teachers’ instructional supervisory practices and teachers’ motivation in teaching. The study was correlational and survey technique was used for data collection. The population of the study was all the male and female head teachers and teachers working in the Government Secondary schools of District Sargodha. Multistage sampling technique was used to select the research participants from 75 randomly selected Government high schools of tehsil Sargodha, 75 head teachers and 225 teachers were selected on availability basis. Two self-developed questionnaires one for head teachers and other questionnaire for teachers pertaining were used. After pilot testing, Cronbach alphas reliability of both the questionnaires were 0.720 and 0.886 respectively. Descriptive statistics and Pearson r correlation were used to analyze the data. The conclusions were that majority of the head teachers were using excellent instructional supervisory practices and majority of the teachers had excellent or good motivation level. There was positive and moderate relationship between head teachers’ instructional supervisory practices and teachers’ motivation. It was recommended that DSD should arrange trainings for the head teachers to improve their inspection skills.
Phytochemicals, Heavy Metal and Proximate Analysis of Parkia biglobosa and Three Varieties of Bouillon Cubes (Purchased From Iyana Iba Market, Ojo Local Government Area in Lagos, Nigeria

Despite the huge nutritional values and availability of local seasonings such as Parkia biglobosa, knorr chicken as food seasonings, some developing countries like Nigeria require more information on the needs for increasing their utilization. Analysis was done using standard analytical methods, to compare the nutritional and heavy metal composition of P. biglobosa seed and bouillon cubes (Knorr chicken, magi star and Tasty cubes). The specific focus was to find out the proximate analysis (carbohydrate, fat, protein and vitamin), heavy metals, Minerals and phytochemicals composition of P. biglobosa and bouillon cubes. Atomic absorption spectrometry was used in the determination of the levels of (Ca, Mg, K, Na, Mn, Fe, Cu and Zn). Phytochemicals, including phytic acid, tannins, carotenoids, phenols, saponins and hydrocyanic acid were also determined using method of Ola and Oboh [19]. The result shows that the seeds of P. biglobosa had significantly higher (p<0.05) Moisture (17.530±3.686) crude protein (25.722±3.524%), crude fat (27.536±2.273%) and Crude fiber (6.540±1.795%) contents compared to the bouillon cubes (Knorr chicken, Maggi Star, tasty cubes). The bouillon cubes had significantly higher (p>0.05) contents of ash (22.188±0.950, 24.092±0.911, 22.880±0.736) which is found to be low in P. biglobosa seed. Carbohydrate level in bouillon cubes were also found to have higher means values of (28.87±1.581, 46.785±2.243, 38.035±12.574). The minerals content of the analyzed samples shows that the P. biglobosa seeds have higher means value in Ca (126.285±16.393), Na (150.820±25.075), and K (1454.432±199.575) and bouillon cubes were also found to be high in (Ca, Na , K , Fe), respectively. While the values of (Mn, Zn, Cr Cb, Pb pH) were found to have low mean value which were higher than WHO permissible limits. For the ANFs, P. biglobosa seeds recorded higher levels of Phytic acid (31.171±8.369 mg/100g), saponins (15.767±4.663 mg/100g) and tannins (55.772±6.655 mg/100g), Total carotenoids (41.561±2.632), Total phenols (65.689±14.439), Hydrocyanic acid (7.618±1.922mg/100g) and Ascorbic acid (101.025±11.670 mg/100g) while it was not detected (ND) in bouillon cubes on analysis. T he heavy metal contents in P. biglobosa was found to be high in copper with mean value of (2.478±2.077) while it was found to be insignificant in (Cr, Cb, and pb) and are not within the recommended value by WHO. The overall results are suggestive of higher nutritional quality of the Parkia biglobosa seeds than the bouillon cubes. It was therefore recommended that information concerning the use of local seasonings should be made available through public awareness campaign.
Does FDI inflow crowd in private investment? Empirical evidence for the Southeast region of Vietnam from the panel quantile regression approach

Well-known to be the most dynamic economic region in Vietnam with the establishment of more export processing zones, high technology parks, and industrial zones, the Southeast region is increasingly attracting more capital flows from all over the world. Does FDI inflow crowd in private investment in this region? To answer this research question, the study examines the effect of FDI inflow on private investment for a sample of 6 provinces/cities of the Southeast region between 2005 and 2019 using the panel quantile regression approach, the difference GMM Arellano-Bond, and the FE-IV estimator. The results show that FDI inflow crowds in private investment in this region. In addition, public expenditure, inflation, and population also promote private investment. These findings suggest some crucial policy implications for local governments in this region to receive more FDI inflows as well as promote private investment.
Topological constraints in early 1 multicellularity favor reproductive 2 division of labor 3

Reproductive division of labor (e.g., germ-soma specialization) is a hallmark of the 11 evolution of multicellularity, signifying the emergence of a new type of individual and facilitating the 12 evolution of increased organismal complexity. A large body of work from evolutionary biology, 13 economics, and ecology has shown that specialization is beneficial when further division of labor 14 produces an accelerating increase in absolute productivity (i.e., productivity is a convex function of 15 specialization). Here we show that reproductive specialization is qualitatively different from 16 classical models of resource sharing, and can evolve even when the benefits of specialization are 17 saturating (i.e., productivity is a concave function of specialization). Through analytical theory and 18 evolutionary individual-based simulations, we demonstrate that reproductive specialization is 19 strongly favored in sparse networks of cellular interactions that reflect the morphology of early, 20 simple multicellular organisms, highlighting the importance of restricted social interactions in the 21 evolution of reproductive specialization. 22
Effects of Hydroxyurea Treatment on Haemolysis in Patients with Sickle Cell Disease at Muhimbili National Hospital, Tanzania

Tanzania is one of the countries with a high burden of sickle cell disease (SCD). Haemolytic anaemia is a clinical feature of SCD, and has been linked to major complications leading to morbidity and mortality. Treatment with hydroxyurea (HU) has shown to induce foetal haemoglobin (HbF) which in turn decreases haemolysis in patients. This study aimed to investigate the effects of HU on haemolysis in SCD patients attending Muhimbili National Hospital, Tanzania by comparing their haemolytic parameters before and after therapy. Patients meeting the criteria were initiated on HU therapy for 3 months. Two haemolytic biomarkers: unconjugated plasma bilirubin levels and absolute reticulocyte counts were measured from patients’ blood samples at baseline and after 3 months of HU therapy and compared. Both absolute reticulocyte counts and indirect plasma bilirubin levels significantly declined after HU therapy. Median (IQR) plasma unconjugated bilirubin levels dropped significantly from 20.3 (12.7–34.4) μmol/L to 14.5 (9.6–24.1) μmol/L (p < 0.001) and mean (SD) absolute reticulocyte counts dropped significantly from 0.29 (0.1) x 109/L to 0.17 (0.1) x 109/L (p < 0.001) after therapy, thus, a decline in both haemolytic biomarkers after treatment was observed. This study found a potential for use of HU therapy in managing SCD patients in our settings evidenced by improvements in their haemolytic parameters. Clinical trials with a lager sample size conducted for a longer time period would be beneficial in guiding towards the inclusion of HU in treatment protocols for the Tanzanian population. Keywords: Sickle cell disease; hydroxyurea; haemolysis; foetal haemoglobin
Effect of sucrose on the fatty acid metabolism of adventitious root cultures in vitro of Stevia rebaudiana

In this study, the effect of sucrose on the neutral lipid profile of adventitious root cultures of Stevia rebaudiana was evaluated. The cultures were obtained employing a roller bottle system. In this system, Schott-type flasks were used, which contained Murashige and Skoog liquid medium at 33.3% strength (MS/3) supplemented with 30, 60, and 80 g L-1 of sucrose, respectively, and 10.7 mM 1-naphthaleneacetic acid (NAA). The spectroscopic analyzes showed that the portion of polyunsaturated fatty acids (PUFAs) was highest in roots treated with 30 g L-1 of sucrose. The spectrometric analyzes showed that the palmitic acid was found to be present in relatively higher amounts in the roots submitted to the MS/3-30 g L-1 (31.9%) and MS/3-60 g L-1 (29.5%) sucrose treatments, and lower in the treatment with MS/3-80 g L-1 (28.8%) of sucrose. Also, the treatment using 30 g L-1 of sucrose was the best for obtaining unsaturated fatty acids (UFAs) in the culture, with a relative percentage of 62.9%. Our results indicate that the MS medium that received 30 g L-1 of sucrose induced a lesser abiotic stress condition, which favored PUFAs production in the adventitious root cultures of S. rebaudiana.
Desmoplastic Fibroma and Cemento Ossifying Fibroma of The Anterior Maxilla: A Rare Case Report

Tumors located in the maxillofacial part of the body were classified by WHO in 2017 and among these are intraosseous form of fibromatosis known as Desmoplastic and Cemento-ossifying fibromas. These tumors usually occur in the head and neck region, especially in the mandible and are relatively rare in the maxilla. Meanwhile, this study aims to discribe a rare case of the cemento ossifying fibroma that had been previously diagnosed as desmoplastic fibroma with a mass tumor in the anterior of the maxilla. A 22 years old female reported to the Cipto Mangkusumo Hospital with the main complaint of a lump in the right side of the upper jaw which appeared 2 years prior to the operation. In April 2017, the patient had a biopsy in Tarakan Hospital and the result was a desmoplastic fibroma. Due to the lump enlargement, the patient was admitted to RSCM in July 2019 and had biopsy incision with a diagnosis of cemento ossifying fibroma which was confirmed by the histopathological examination and histology report. The resection of the right part of maxilla was conducted alongside with reconstruction using the free fibular flap. Moreover, cemento ossifying fibroma and desmoplastic fibroma shared similar features, namely, clinical, histological and radiological features which are important in establishing the diagnosis and treatment of patient. Hence, extensive enucleation or resection is required due to the progressive nature of the tumor to prevent the potential for further recurrences.
Clay mineralogy of subtropical soils under long-term organic fertilization in no-tillage systems.

ABSTRACT: Organic fertilization effect on physical-chemical properties in no-tillage systems in tropical soils has been widely investigated, but little is known about the effects of this practice on the mineralogy of the clay fraction. This study aimed to evaluate the clay-fraction mineralogy of two subtropical soils, fertilized with organic residues in long-term no-tillage systems. An Alfisol fertilized with 0, 40, and 80 m3 ha-1 yr-1 pig slurry was evaluated for eight years, and an Oxisol with 0, 8, and 16 [. ]
Impulsive Buying Behavior in Mobile Apps Online Travel Agent (OTA) Users: The Role of Apps Browsing and Sales Promotion

This study tries to explore the phenomenon of impulsive buying among Online Travel Agent (OTA) users who are influenced by the presence of sales promotion activities by OTA and consumer actions when searching for travel products offered by OTA through the mobile apps platform. Research data collection is done through the distribution of questionnaires arranged in a structured way to answer the formulation of the research problem. The questions included in the questionnaire all adopt the results of previous studies with a level of validity and reliability that can be scientifically guaranteed. Questionnaires were distributed to OTA mobile apps users who have accounts in various types of OTAs and have made purchases of products offered by OTA in the past 1 year. A total of 106 respondents participated in filling out the questionnaire from 150 questionnaires that had been distributed previously. The results show that apps browsing does not affect the impulsive behavior of OTA customers and conversely sales promotion can significantly influence impulsive buying.
Wine Ratings and Advertising Strategies: Is There a Link?

Advertising is one of the most widely used marketing resources in the beverage industry, yet the wine industry has not made an intense use of this resource over time. The small average size of wineries together with rising concerns about the effectiveness of advertising has led many wineries to use alternative strategies to market their products: collective brands, the display of prizes and medals on their labels, or positive ratings in expert guides. In this sense, the objective of the present study was to analyse the behaviour of wineries regarding their use of advertising as a marketing resource. Specifically, we analysed the advertising strategy of wineries with respect to the existence of publicly available wine ratings. The method was based on the estimation of a Heckit model that simultaneously identifies the variables underlying the decision to invest in advertising and the determinants of the amount of money invested. The results revealed a nonlinear relationship between wine ratings and advertising investment.
A new species of Pareas (Squamata, Pareidae) from southern Vietnam

Abstract We describe a new species of pareid snake from the Di Linh Plateau in Lam Dong Province of southern Vietnam based on morphological and molecular evidence. Pareas temporalissp. nov. is distinguished from its congeners by having the combination of yellow-brown body colouration; hexagonal-shaped frontal, with lateral sides parallel to the body axis; 16–17 temporals, with 4–5 anterior temporals; loreal and prefrontal not contacting eye; 2–3 preoculars; two suboculars; 2–3 postoculars; 8–9 supralabials; 8–9 infralabials; 15–15–15 dorsal scale rows, all keeled, three vertebral scale rows enlarged; 191 (+1 preventral) ventrals, smooth; 92 subcaudals, all divided; undivided anal scale; two postocular stripes; and a solid dark brown vertebral stripe extending from rear of nuchal collar along the entire length of body and tail. Phylogenetic analyses of mitochondrial DNA data recovered the new species to be nested within the P. carinatus complex and to be the sister taxon to P. nuchalis from Borneo.