Miracle-dz/UniFAR-FTUs huggingface dataset:
Digestive Involvement in SARS-CoV-2 Infection: A Retrospective Multi-center Study

BackgroundCoronavirus disease 2019 (COVID-19) is an emerged infection raised wide concerns for the pneumonia and respiratory manifestations. Also, digestive complications are frequently observed in COVID-19 patients but the significance remains undetermined.MethodsA retrospective analysis of alimentary symptoms, liver dysfunctions and other clinical parameters of 514 hospitalized COVID-19 patients (282 mild, 162 severe and 70 critical cases) admitted to the 3 designated medical units of Wuhan Union Hospital from Jan 20 to Feb 29, 2020 was performed.Results1) A series of alimentary symptoms, including poor appetite(50.2%), diarrhea(25.5%), nausea(16.3%), vomit(11.9%) and abdominal pain(3.3%), presented in COVID-19 patients.2) Diarrhea was common gastrointestinal symptom with higher morbidity in the severe and critical patients (32.1% and 27.1% respectively), and 13.2% patients developed diarrhea in the first 3 days after onset of symptoms. Those with diarrhea were reported more apparent systemic inflammation and liver injury in severe and critical cases compared with patients without diarrhea.3) Notably, 31 patients (6.03%) presented with diarrhea in the absence of respiratory symptoms. These patients were observed less systemic inflammatory activity relative to diarrhea patients combined with respiratory symptoms.4) Also, liver injury was high incident in COVID-19 patients with increased alanine aminotransferase (43.3%), aspartate transaminase (36.7%) and decreased albumin (80.9%), but less increased total bilirubin (10.9%) and direct bilirubin(14.2%), which were more serious in the severe to critical patients.ConclusionsOur data favored in the process of novel SARS-CoV-2 infection. There may be a “gut-type” in the clinical prevention and management that differ from the “lung-type” in COVID-19 sufferers.
Validation of a Patient Questionnaire Assessing Patient Satisfaction With Orthopedic Outpatient Clinic Consultation

Previous qualitative research has identified a number of factors which influence patient satisfaction with orthopedic outpatient clinic visits. To further evaluate these factors, the authors initially generated a number of items or statements representing these factors. This cohort of items was then subjected to analysis by an expert group to assess which 3 items best represented each factor. These items formed the basis of a draft survey which was then administered to 323 orthopedic outpatients to assess these factors as characteristics of patient satisfaction. Items and factors were also assessed against 2 global measures of patient satisfaction. One hundred and one survey responses were returned and subjected to factorial analysis. Results indicated that factors of trust, empathy, and relatedness were not distinguishable and subsequently combined to represent a single factor, the therapeutic relationship. A final 5-factor model is proposed incorporating 3 interpersonal factors (communication, expectation, therapeutic relationship) and 2 environmental factors (clinic wait time, clinical contact time). The factors identified by this study should be considered in surveys evaluating patient satisfaction with orthopedic outpatient services.
Interpersonal Conflict over Water Is Associated with Household Demographics, Domains of Water Insecurity, and Regional Conflict: Evidence from Nine Sites across Eight Sub-Saharan African Countries

Water insecurity may precipitate interpersonal conflict, although no studies to date have rigorously examined these relationships. We examined relationships between household demographics, water insecurity, regional conflict, and interpersonal conflict over water. Using survey data from eight sub-Saharan African countries, we found that interpersonal conflict within and outside the home is associated with multiple domains of water insecurity, particularly accessibility. Furthermore, we found that higher levels of remote violence and protests are associated with greater within household conflict, whereas riots and violent armed conflict are associated with greater conflict between neighbors. Our findings expand upon the current literature by examining factors affecting interpersonal conflict over water, which may become increasingly important as precipitation patterns and land temperatures change in this region.
Documentation of floristic diversity & traditional knowledge: A case study of Block Bhunga, district Hoshiarpur, Punjab (India)

India is land of biological and cultural diversity and one of the17 mega-biodiverse countries in the world. It is also the home of large number of tribal groups, nomadic groups, farming and fishing communities. These communities have different kinds of nature-based livelihoods and therefore have traditional knowledge of varying degrees . In present times, t (NBA, 2013) he use of traditional knowledge (TK) is not restricted to the lives and livelihoods of these communities. Now a days, the demand of natural, herbal and organic products especially prepared by traditional methods is increasing globally. The industries of herbal medicine, cosmetics and personal care are the major users of these resources. This increased market demand of bio-resources and associated TK is offering new opportunities to the indigenous and local communities for generating benefits and enhancing incomes. On the contrary, cases of biopiracy and misappropriate use of traditional knowledge are becoming more common. The main reason for this misappropriation is to obtain traditional knowledge f reely among the local c o m m u n i t i e s a n d l a c k o f p r o p e r documentation of this valuable knowledge (Pant, 2015). The Government of India introduced the “Biological Diversity Act 2002” to act on the objectives of Convention on Biological Diversity. This Act proposes the constitution of Biodiversity Management Committees (BMCs) at local level for the safeguarding and documentation of biodiversity and associated traditional knowledge within their area of jurisdiction in the form of People's Biodiversity Registers (PBRs).
Prognostic Significance of the Preoperative Prognostic Nutritional Index in Epithelial Ovarian Cancer Patients: A Systematic Review and Meta-analysis of Cohort Studies

BackgroundThe main aim of this study was to validate the potential association between the preoperative prognostic nutritional index (PNI) and survival of patients with ovarian cancer (OC). MethodsWe systematically searched multiple databases (PubMed, EMBASE, and Web of Science) for publications up to June 30, 2019, to identify observational studies evaluating the PNI in relation to survival. Two reviewers independently extracted data and assessed the quality of each study using the Newcastle-Ottawa Scale (NOS). Summary hazard ratios (HR) and 95% confidence intervals (CI) were calculated with the aid of a random-effects model. The potential for publication bias was explored using Funnel plots as well as Begg’s and Egger’s tests.ResultsAmong the 15,000 studies selected for selection, 5 retrospective cohort studies (4 from China and one from Japan) comprising 1964 OC patients met the inclusion criteria. All studies were graded as ‘low risk of bias’ according to NOS. A low preoperative PNI was associated with poor overall survival (HR = 1.69, 95% CI = 1.16–2.46; I2 = 83.8%) and progression-free survival (HR = 1.86, 95% CI = 1.39–2.51; I2 = 29.7%) of OC patients. No significant publication bias was detected.ConclusionsCollective data from the present systematic review and meta-analysis suggest that a low preoperative PNI is associated with poor survival in OC. Further prospective studies are required to confirm these findings.
Clinical Characteristics and Cardiovascular Implications of 116 Hospitalized Patients with COVID-19 in Wuhan, China: A single-Centered, Retrospective, Observational Study

Background Corona Virus Disease 2019 (COVID-19) caused by 2019 novel coronavirus (SARS-CoV-2), has become a global pandemic. Aged population with cardiovascular diseases are more likely be to infected with SARS-CoV-2 and result in more severe outcomes and elevated case-fatality rate. Meanwhile, cardiovascular diseases have a high prevalence in the middle-aged and elderly population. However, despite of several researches in COVID-19, cardiovascular implications related to it still remains largely unclear. Methods 116 patients with laboratory-confirmed COVID-19 were enrolled, who admitted to the General Hospital of Central Theater Command (Wuhan, China) from January 20 to March 8, 2020. The demographic data, underlying comorbidities, clinical symptoms and signs, laboratory findings, chest computed tomography, treatment measures, and outcome data were collected from electronic medical records. Data were compared between non-severe and severe cases.Results Of 116 hospitalized patients with COVID-19, the median age was 58.5 years (IQR, 47.0-69.0), and 36 (31.0%) were female. Hypertension (45 [38.8%]), diabetes (19 [16.4%]), and coronary heart disease (17 [14.7%]) were the most common coexisting conditions. Common symptoms included fever [99 (85.3%)], dry cough (61 [52.6%]), fatigue (60 [51.7%]), dyspnea (52 [44.8%]), anorexia (50 [43.1%]), and chest discomfort (50 [43.1%]). Lymphopenia (lymphocyte count, 1.0 × 109/L [IQR, 0.7-1.3]) was observed in 66 patients (56.9%), and elevated lactate dehydrogenase (245.5 U/L [IQR, 194.3-319.8]) in 69 patients (59.5%). Compared with non-severe cases, severe cases were older (64.0 years [IQR, 53.0-76.0] vs 56.0 years [IQR, 37.0-64.0]), more likely to have comorbidities (35 [63.6%] vs 24 [39.3%]), and more likely to develop acute cardiac injury (19 [34.5%] vs 4 [6.6%]), acute heart failure (18 [32.7%] vs 3 [4.9%]), and ARDS (20 [36.4%] vs 0 [0%]). During hospitalization, the prevalence of new onset hypertension was significantly higher in severe patients (55.2% vs 19.0%) than in non-severe ones. Conclusions We found that the infection of SARS-CoV-2 was more likely to occur in aged population with cardiovascular comorbidities. Cardiovascular complications, including new onset hypertension and heart injury were common in severe patients. More detailed researches in cardiovascular involvement in COVID-19 are urgently needed to further understand the disease.
Design of the blended learning course in engineering education

Blended Learning is a flexible learning model that combines the creative advances and technology of online learning with the interaction and engagement of face-to-face learning. One of the best ways to deal with the need for "learning anywhere, learning anytime, learning everything, learning flexibly, learning openly and learning for the whole life", which becomes an inevitable trend currently. This requires teachers to design a course and organize the teaching process to assure the formation and development of learners’ self-learning ability as well as the cultivation of the skills in using and mastering technology. The paper outlines the theoretical model and steps to be taken to design a blended learning course to help teachers in the course design suitable for their teaching process at university meeting the fourth industrial revolution.
Water speciation in rhyolitic melt determined by in-situ infrared spectroscopy

Abstract Near-IR spectra obtained from hydrous silicate melts, close to natural rhyolite, were acquired at both high temperature using a heating stage and simultaneously at high pressure and temperature using a hydrothermal diamond cell. The temperature dependence of the extinction coefficients for the peaks due to OH and H2O is negligible. In both sets of experiments, the speciation reaction H2O + O = 2OH is shifted to the right with increasing temperature above the glass transition but changes below this are negligible, within experimental uncertainty. For a sample containing 3.93 wt% total water, the temperature dependence of the speciation equilibrium can be described by two equations with temperature in K: ln k = -36.74/T - 4.02 for the glass phase (giving enthalpy and entropy of reaction values of ΔH = 0.31 kJ/mol and ΔS = -33.45 J/mol-K), and ln k = -3821.83/T + 1.61 for the melt phase (where ΔH = 31.77 kJ/mol and ΔS = 13.41 J/mol-K) respectively). The glass transition temperature of 670 K is defined by the intersection of these curves. Our values are in good agreement with previously published glass transition temperatures for similar compositions. Similar values for the enthalpy and entropy of reaction were obtained from all the other experiments including those at pressures up to 4.5, 5, and 10 kbars, suggesting that the speciation depends negligibly on pressure for this pressure range.
Research on the relationships between destination image, perceived value and tourism experience of gastronomy tourism--A case of Macao Food Tourists

Gastronomy tourism, as a new tourism mode with special interest, can not only stimulate tourists’ interest in experiencing local traditional food, but also better meet tourists’ personalized experience needs, which is highly respected by the tourism market. Based on the research of scholars at home and abroad, this paper takes Macao food tourists as the research object to study the relationship among tourism experience, perceived value and destination image. The results show that the tourism experience of Macao food tourists has a significant positive impact on their perceived value and destination image, while the perceived value of tourists has a significant positive impact on their destination image. Based on the above research results, this paper puts forward several suggestions for the sustainable development of Macao’s gastronomy tourism and makes a little contribution to the development of Macao’s gastronomy tourism.
Severe Acute Respiratory Syndrome Coronavirus-2 and Pulmonary Tuberculosis Coinfection: Double Trouble

Background: The ongoing pandemic of novel coronavirus disease 2019 (COVID-19) has received worldwide attention by becoming a major global health threat. We encountered one case with COVID-19 and tuberculosis (TB) coinfection which has not been frequently reported. Case presentation: A 76 year old female presented with acute respiratory symptoms superimposed on chronic symptoms, suggestive to have pneumonia. Oropharyngeal throat swab sample for COVID-19 was positive as detected by real-time reverse-transcriptase–polymerase-chain-reaction (RT-PCR) assay. GeneXpert Ultra detected Mycobacterium tuberculosis complex with Rifampicin resistance indeterminate. Patient was treated with appropriate management. Conclusion: Clinicians should suspect coinfection with TB during ongoing pandemic of COVID-19 as therapeutic strategies need to be determined timely to improve outcome and prevent transmission in community.
Preservation of cerebrospinal fluid cells to investigate intrathecal immunity in neurodegeneration

Background: Cerebrospinal fluid (CSF) provides basic mechanical and immunological protection to the brain. Historically, analysis of CSF has focused on protein changes, yet recent studies of neurodegenerative diseases have shed light on cellular alterations. Due to low cell numbers in the CSF, only recently have advances in molecular biology techniques allowed for the investigation of disease-related cellular changes. Chief among these advances is single cell RNA sequencing (scRNAseq). However, concerns such as batch effects and time constraints call for a standardized method for long-term preservation of CSF immune cells. Results: We present a method for long-term cryopreservation of CSF immune cells for downstream scRNAseq analysis. Cells can be analyzed up to two years following CSF collection. On average, 4,961 live cells can be recovered from 10 mL CSF after cryopreservation, with no association between length of storage and cell viability. We demonstrate that scRNAseq detects CD8 + and CD4 + T cells, natural killer cells, plasma cells, B cells, and innate immune cells (monocytes and dendritic cells) within the CSF of 24 subjects. Conclusions: The ability to store CSF cells long-term will enable researches actively collecting CSF to investigate intrathecal immunity. This method will aid in the understanding of cellular and molecular changes to CSF immunity in neurodegenerative diseases.
Identification of Methylhopane and Methylmoretane Series in Ceará Basin Oils, Brazil, Using Comprehensive Two-Dimensional Gas Chromatography Coupled to Time-of-Flight Mass Spectrometry

Comprehensive two-dimensional gas chromatography coupled to time-of-flight mass spectrometry (GC × GC-TOFMS) was used to identify methylhopanes in oils. 2α-Methyl-17α(H),21β(H)-hopane and 2α-methyl-17β(H),21α(H)-hopane (2α-methylhopane) series were found in oils from Ceara Basin, Brazil. In the 3β-methylhopane series, only C31 3β-methyl-17α(H),21β(H)-hopane was detected. In addition, a novel terpane series (C30−C34), which eluted after the regular hopanes (comparing compounds of both families with the same carbon number) either in 1D (first dimension) or 2D (second dimension), was identified. A compound likely to be bisnorgammacerane was separated from C29 25-norhopane in the 2D, and consequently identified. An unusual compound pair eluting after the C35R moretane was tentatively identified as C36 17α(H),21β(H)-homohopanes (22S, 22R). The presence of 2α-methylhopanes in oils from Ceara Basin may indicate oxygen-producing cyanobacteria were important biological inputs in the deposition environment. This is.
Phytochemical Screening and In vitro Anthelmintic Activity of Cassia alata (L) Roxb. on Haemonchus contortus of Small Ruminants in Burkina Faso.

| In Burkina Faso, small ruminant livestock owners face internal parasitism, particularly gastro-intestinal strongylosis (GIS), which causes severe losses on their farms. In response to this situation, endogenous strategies are being developed through the use of medicinal plants such as Cassia alata to combat GIS in the field. Thus, the present study was conducted to evaluate the anthelmintic efficacy of aqueous and hydroacetonic extracts of Cassia alata leaves on Haemonchus contortus, one of the most dominant strongles of small ruminants in Burkina Faso. For this purpose, a phytochemical screening of two extracts was carried out followed by in vitro antiparasitic tests with five increasing concentrations (6.25, 12.5, 25, 50 and 100 mg/ml) of the extracts on two stages life of the Haemonchus contortus parasite. The results obtained from the phytochemical analysis revealed the presence of steroidal and triterpenic compounds, anthracenosides, saponosides, polyphenols (tannins) and reducing compounds in the aqueous and hydroacetone extracts of the leaves of Cassia alata. In the in vitro tests, the percentages of egg hatch inhibition increased significantly (p˂0,05) with increasing concentrations and compared to the control. All concentrations tested showed vermicidal activity on adult Haemonchus contortus worms after 6 hours of exposure to freeze-dried extracts. These results show that both extracts have ovicidal and vermicidal activity on the Haemonchus contortus parasite. Further studies could be envisaged to evaluate the toxicity of the plant extracts followed by in vivo anthelmintic efficacy tests to support breeders in their use.
Access to Collateral and the Democratization of Credit: France's Reform of the Napoleonic Security Code

France's Ordonnance 2006‐346 repudiated the notion of possessory ownership in the Napoleonic Code, easing the pledge of physical assets in a country where credit was highly concentrated. A differences‐test strategy shows that firms operating newly pledgeable assets significantly increased their borrowing following the reform. Small, young, and financially constrained businesses benefitted the most, observing improved credit access and real‐side outcomes. Start‐ups emerged with higher “at‐inception” leverage, located farther from large cities, with more assets‐in‐place than before. Their exit and bankruptcy rates declined. Spatial analyses show that the reform reached firms in rural areas, reducing credit access inequality across France's countryside.
Evaluating Factors Affecting User Satisfaction in University Enterprise Content Management (ECM) Systems

Higher learning institutions (HLIs) are implementing enterprise content management (ECM) systems as web portals that are helping them interact with and serve their students better. However, there is a paucity of research that has evaluated the factors that account for students using their university’s portals. As a case study and using the D&M IS Success Model as a guiding lens, this paper explored the factors that influence Limkokwing University of Creative Technology (LUCT) Students to use the university’s portal through a survey. Data was collected from 134 students through Stratified Random Sampling technique that was analysed through Partial Least Square ‑ Structural Equation Modelling (PLS‑SEM). Results obtained show clearly that LUCT students are using the university’s portal as a result of the System Quality and Information Quality which gives them Satisfaction. However, the findings reveal no significant correlation between Service Quality and Satisfaction of the students as well as the System Quality and Behavioural Intention (BI) to use the Systems. This study has given more insights into LUCT Management, Administrators, and Faculties concerning how to handle their Students need. Other implications for both practice and theory were also discussed.
Interplay among physical balance ability, physical activities realization, anthropometric parameters and psychosocial indices in relation to gender and age of seniors 65+

Introduction: The study is aimed to analyze the interplay among the physical balance level, physical activities realization, anthropometric determinants and psychosocial indices in relation to gender and age of seniors 65+. Methods: The participants comprised 500 seniors in age 65+ (234 males and 266 females) participated voluntarily in the research. For data collection we used methods of the “Medical anamnesis”, “Tinetti Balance Assessment Tool”, “Health Survey SF-36”. For statistics analyses the multivariate regression with reduction of dimensionality and orthogonal projection to latent structure was used. Results: Analyzed disabilities “Depression”, “Type 2 diabetes mellitus”, “Hypertension” and “Vertigo” significantly negatively interplay with the Tinneti summary balance score in both genders. Results of the anthropometric parameters of female seniors, in a contrast to the male seniors parameters, proved that body high and muscle mass correlate significantly positively with the performance of the Tinneti summary balance test (p<0.01) in female seniors. Conclusion: Performing of physical activities positively correlates with the performance in the Tinneti summary balance test in both genders of seniors. There are differences between male and female seniors according the psychosocial factors interplay with performance in the Tinneti summary balance test, when more interplaying psychosocial factors were analyzed in females.