Miracle-dz/UniFAR-FTUs huggingface dataset:
Estimating deformation demands on steel EBF systems

The deformation capacity of a steel eccentrically braced frame (EBF) structure is typically governed by the chord rotation capacity of the EBF links. Codes allow these chord rotation demands to be estimated a variety of ways, from simplified hand calculations through to advanced non-linear analyses. Recent studies have suggested that the elastic analysis approach recommended by the New Zealand steel industry may be non-conservative. Consequently, this paper compares the deformations predicted by current industry recommendations with the results obtained from nonlinear static pushover analyses for a series of multi-storey EBF structures. To better estimate the actual link rotation demands in design, a simplified displacement-based method is also used, identifying three deformation components (links, braces and columns) and their contributions to storey drifts. Through a series of case studies, the deformation-component method is shown to perform well, giving more accurate predictions of the actual displacement profiles and link rotation demands of multi-storey EBF structures compared to the current industry guidelines. Therefore, it is recommended that the industry consider replacing current guidelines for estimation of rotation demands on EBF links with a deformation component approach.
The Big 5 Personality Traits And Its Relation With Creativity

Creativity has been acknowledged as one of the predominant factors influencing individual’s contribution in various domains of life. History shows, that creative people possess unusual traits which make them different from their less creative counterparts. The present study was carried out on a group of reputed creative persons (national award winners) in the field of performing arts, visual arts and innovators in the area of science and technology. The total sample size is 180 (50 performing artists, 50 visual artists, 30 innovators, and 50 corporate executives which constituted the control group) aged between 30-65 years. For this purpose Standard Progressive Matrices developed by Ravens (1996) was used for screening purpose, in addition to the NEO-FFI-3 (Costa and McCrae, 1992) which was used to assess the Big 5 personality areas of openness to experience, conscientiousness, extraversion, agreeableness and neuroticism. To achieve the objectives Mean, SD, Kruskal Wallis ‘H’ test followed by MaanWhitney ‘U’testwere the statistical tests used. Finally discriminant analysis was applied to strengthen the predictive validity of the test. Results yielded that out of the three creative groups, innovators were found to have a significantly higher mean value on openness to experience and conscientiousness, performing artists were found to have a significantly higher score on extraversion and agreeableness while visual artists were found to score high on neuroticism. Finally, openness to experience was found to be the most discriminating factor between the creative and the less creative (corporate executives).
The Influence of Communication Environment to the Brainstorming Practice.

Chang-Gung University Brainstorming is known as the most common method used for idea generation by group effort with time-limit. Instead of the development of various form of brainstorming to enrich the brainstorming result, the computer-based tools is developed and used to support the conduction of brainstorming by providing the functions, such as voting, database, information retrieving. Such tools are often integrated into computer-supported group meeting system. However, such integrated systems, often used for large size meeting room allowing tens of people meeting together and cost relative much, are unlikely favor to middle and small size company due to the consideration in cost and the limit in usability. For example, a studio-like design office might hesitate to install such systems to assisting their brainstorming, particularly in the case where the colleagues are separated at a distance which is often seen in the organization of modern design office.
Neighbourhood characteristics and the labour market experience: A qualitative analysis of the second generation Ghanaian-Canadians in the Greater Toronto Area (GTA)

Neighbourhood characteristics pose challenge in labour market participation for immigrants and their children in many immigrants receiving countries, including Canada. The purpose of this study was to explore the effect of living in disadvantaged neighbourhoods on labour market participation amongst the second generation youth. Grounded in focus groups and in-depth interviews, our analysis underscores the importance of understanding neighbourhood characteristics and implication on labour market participation amongst the second generation Ghanaian-Canadians in the Greater Toronto Area, specifically, Jane-Finch and Brampton. Our findings reveal several areas where neighbourhood characteristics impact on labour market participation of the second generation youth: neighbourhood’s reputation, inefficient transit system and inadequate jobs in neigbourhoods. Based on our findings, we offer recommendations that may be of interest to decision-makers in government, social services and health agencies in urban centres.
COUMESTROL CONTENT IN ALFALFA BREEDING POPULATIONS

Alfalfa (Medicago sativa L.) is the most signifi cant perennial forage legume in the production of high quality and nutritionally valuable fodder for livestock feed, primarily ruminants (Vasileva, 2013; Tucak et al, 2018). Despite its exceptional value in livestock systems, alfalfa, like many other legume species and varieties, may contain phytoestrogens, the most interesting of which is coumestrol, which express strong estrogenic activity that can adversely affect the reproductive health of domestic animals (Hloucalova et al, 2016; Reed, 2016).
Ovicidal, pupicidal, adulticidal, and repellent activity of Helicteres velutina K. Schum against Aedes aegypti L. (Diptera: Culicidae)

Abstract Aedes aegypti is a vector of emerging and neglected diseases, such as dengue, chikungunya, and Zika. Helicteres velutina, known as “pitó” in Brazil, is traditionally used as an insect repellent, and several studies have demonstrated its larvicidal activity. The aim of this study was to investigate this species and evaluate its potential ovicidal, pupicidal, adulticidal, and repellent activity. The viability of the eggs was evaluated using different concentrations of the test substances for 25 days. The hexane fraction killed 72.7% of the eggs, while dichloromethane killed 67.7%. The survival of the pupae and adults was verified after 72 h and 48 h, respectively. The LC50 for the hexane and dichloromethane fractions was 0.12 mg/mL and 8.85 mg/mL for pupae, 8.01 mg/mL and 0.74 mg/mL for adults (tarsal test), and 0.05 mg/mL and 0.23 mg/mL for adults (body test), respectively. Repellency was assessed for 240 min using neonatal Wistar rats on a Y-tube olfactometer. The hexane fraction attracted mosquitoes to the test chamber, while the dichloromethane fraction had a repellent action. The 7,4’-di-O-methyl-8-O-sulfate flavone provides greater repellency, and this finding is similar to the results of the in silico studies that have shown the potential of this substance against adult mosquitoes. This suggests that 7,4’-di-O-methyl-8-O-sulfate flavone may be one of the substances present in the extract from aerial parts of H. velutina that is responsible for the repellent activity mentioned in traditional medicine. These findings provide a better understanding of the insecticidal and repellent activity of the extract, fraction, and compounds isolated from H. velutina against Ae. aegypti, thereby revealing its potential in the development of a more effective botanical insecticide.
Agricultural extension for promoting citrus fruit growers’ innovation and profitability in Mexico

El citricultor presenta una adopcion baja de innovaciones, lo que contribuye a que sus ingresos y rentabilidad sean menores. El objetivo del presente estudio fue aplicar tecnicas de capacitacion y extension andragogicas a un universo de 150 citricultores de cinco comunidades de Veracruz, Mexico, para que mejoraran la adopcion de innovaciones sociales y tecnologicas, su ingreso y su rentabilidad. El porcentaje de adopcion de innovaciones (PAI) se calculo mediante la siguiente ecuacion: PAI = n/N ×100, donde n fue el numero de innovaciones adoptadas por el productor y N el numero total de innovaciones disponibles en el paquete tecnologico. En el 2012 se aplicaron dos encuestas iniciales: la social y la tecnologica, que revelaron que habia una desarticulacion significativa en las redes de innovacion, sobre todo en las relaciones profundas, y poco uso de innovaciones tecnologicas. Despues de la capacitacion y extension andragogicas, se logro una mayor articulacion, que se reflejo en enlaces mas numerosos y solidos, mas nodos y mayor densidad, en especial en el nivel de confianza, lo que contribuyo a consolidar las redes sociales para el 2014. La categoria tecnologica mas adoptada fue el manejo de la fertilizacion. Con la finalidad de cuantificar la permanencia de la adopcion de innovaciones, se aplico una encuesta en 2016. Se concluye que la intervencion social y tecnologica, implementada con capacitacion y extensionismo andragogicos, permitio mejorar el rendimiento de las huertas en mas del 50 %, aumentar los ingresos de los productores de citricos 4,5 veces mas y consolidar grupos de trabajo y la permanencia de las innovaciones.
Numerical solution of space fractional diffusion equation using shifted Gegenbauer polynomials

This paper is concerned with numerical approach for solving space fractional diffusion equation using shifted Gegenbauer polynomials, where the fractional derivatives are expressed in Caputo sense. The properties of Gegenbauer polynomials are exploited to reduce space fractional diffusion equation to a system of ordinary differential equations, that are then solved using finite difference method. Some selected numerical simulations of space fractional diffusion equations are presented and the results are compared with the exact solution, also with the results obtained via other methods in the literature. The comparison reveals that the proposed method is reliable, effective and accurate. All the computations were carried out using Matlab package.
THE IMPLEMENTATION OF CARE COORDINATION MODEL TOWARD DELIVERY OF QUALITY CARE IN PRIVATE HOSPITAL OUTPATIENT SETTING

Health care services in the private hospitals are required to deliver quality care to stay competitive in the business. In line with the advancement of hospital facilities and the raise of patient needs for complex care, the care coordination is inevitable to ensure the delivery quality of care. The purpose of this study is to test and analyze the care coordination model toward delivery of quality care in the private hospital outpatient setting. This research model was empirically tested on outpatient clinic at one of the leading hospitals in Indonesia. The data was analyzed by PLS-SEM method, whereas respondent obtained by purposive sampling technique. The result of structural model, shown moderate to strong prediction accuracy with large predictive relevance indicate and acceptable model. The result demonstrated that all of care coordination paths lead to the delivery of quality care has significant positive effect, except for facilitate transitions and accountability to communication and information transfer. However, facilitate transitions and accountability has significant positive effect through IT-enabled care coordination and through interprofessional teamwork and consistency. Therefore, it could be concluded that all variables have contribution to the care coordination in the outpatient, respectively. The strongest direct effect to care quality perception is found from communication and information transfer, while the strongest indirect effect is from physical infrastructure and facilities which mediating by IT-enabled care coordination and further communication and information transfer. There are managerial implications that could give suggestions for hospital managers to improve care coordination process in hospital outpatient services.
Evolving Phenotypes of non-hospitalized Patients that Indicate Long Covid

Many of the symptoms characterized as the post-acute sequelae of SARS-CoV-2 infection (PASC) could have multiple causes or similarly seen in non-COVID patients. Accurate identification of phenotypes will be important to guide future research and the healthcare system to focus its efforts and resources on adequately controlled age- and gender-specific sequelae of COVID-19 infection. In this retrospective electronic health records (EHR) cohort study, we applied a computational framework for knowledge discovery from clinical data, MLHO, to identify phenotypes that positively associate with a past positive PCR test for COVID-19. We evaluated the post-test phenotypes in two temporal windows at 3-6 and 6-9 months after the test and by age and gender. We utilized longitudinal diagnosis records stored in EHRs from Mass General Brigham (MGB) 57 thousand patients who tested positive or negative for COVID-19 and were not hospitalized. Statistical analyses were performed on data from March 2020 to March 2021. PCR test results and subsequent diagnosis records that were recorded for the first time two months or later after the PCR test. We identified 28 phenotypes among different age/gender cohorts or time windows that positively associated with past SARS-CoV-2 infection. All identified phenotypes were newly recorded in patients' medical records two months or longer after a COVID-19 PCR test in non-hospitalized patients regardless of the test result. Among these phenotypes, a new diagnosis record for anosmia and dysgeusia (OR 2.17, 95% CI [1.42 - 3.25]), alopecia (OR 3.54, 95% CI [2.92 - 4.3]), chest pain (OR 1.35, 95% CI [1.16 - 1.56]), or chronic fatigue syndrome (OR 1.81-2.28, 95% CI [1.38 - 3.68]) are the most significant indicators of a past COVID-19 infection, especially among women younger than 65. Among men, edema (OR 1.83, 95% CI [1.23 - 2.66]) and disease of the nail (OR 3.54, 95% CI [1.63 - 7.29]) in patients 65 and older or proteinuria (OR 2.66, 95% CI [1.61 - 4.34]) in patients under 65 are associated with a positive COVID-19 PCR test in the past few months. Our approach avoids a flood of false positive discoveries while offering a more probabilistic flexible criterion than the standard linear phenome-wide association study (PheWAS). These findings suggest that some of the previously identified post sequelae of COVID-19 may not be accurate and that most of the PASC are observed in patients under 65 years of age.
Evaluation of the effects of seasonal raw materials and processing stages in feed mills implementing the HACCP system on mycotoxin content in feed

This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial license (http://creativecommons. org/licenses/by-nc/4.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. Evaluation of the effects of seasonal raw materials and processing stages in feed mills implementing the HACCP system on mycotoxin content in feed
Polyaminoacid–doxorubicin prodrug micelles as highly selective therapeutics for targeted cancer therapy

An amphiphilic copolymer carrying high-dose doxorubicin (21% on a weight basis), PHEA–EDA–P,C–Doxo, was prepared by coupling doxorubicin with a biocompatible polyaminoacid through a pH-sensitive spacer. Additional derivatization with 4-pentynoic acid endows it with self-assembling properties by means of π–π stacking. These micelles can be triggered to promptly release drug in lysosomes (∼40% in 12 h) through pH-dependent micelle hydrolysis after uptake. In vitro tests on co-cultures of cancer (MDA-MB 231) and normal (HB-2) breast cells proved that the conjugate was selectively internalized into the former rather than normal cells, exploiting the caveolae-dependent endocytosis pathway, explaining the selective cytotoxic effect toward cancer cells. Intracellular trafficking study of MDA-MB 231 showed that the delivery of the endocytosed drug occurs through the direct fusion of caveosomes with late lysosomes, triggering a massive release in the cytoplasm, bringing about cell death. Dose-effectiveness and mechanistic data indicate that PHEA–EDA–P,C–Doxo is endowed with a distinctive combination of selectivity and pharmacological potency (EC50 13 μM, Emax = 77% and EC50 > 25 μM, Emax = 21% for cancer and healthy cells respectively) that makes it an excellent candidate for future preclinical studies.
Frequency Band and PCA Feature Comparison for EEG Signal Classification

The frequency band method is popular in signal processing; this method separates EEG signals into five bands of frequency. Besides the frequency band, the recent research show PCA method gives a good result to classify digits number from EEG signal. Even PCA give a good accuracy to classify digit number from EEG signal, but there are no research shows which one yielded better accuracy between PCA and frequency band to classify digit number from EEG signals. This paper presents the comparison between those methods using secondary data from MindBigData (MDB). The result shows that the frequency band and PCA achieve 9% and 12,5% on average accuracy with the EPOC dataset. The paired Wilcoxon test produces a significant difference in accuracy between methods in the digit classification problem. Experiment with Muse dataset provides 31% accuracy with frequency band method and 24,8% with PCA method. The result is competitive compared to other experiments to classify digit numbers from EEG signals. In conclusion, there is no winner between the two methods since no method fits both datasets used in this research.
ANTHOCYANIN-RICH PHENOLIC EXTRACTS OF BLACK CHOKEBERRY (ARONIA MELANOCARPA) ATTENUATE INFLAMMATION INDUCED BY LIPOPOLYSACCHARIDE IN RAW 264.7 CELLS

Aronia melanocarpa berries and their extracts, have become well known for their notable health benefits. The present study investigated the anti-inflammatory effect of anthocyanin-rich phenolic extracts of Ame (Aronia melanocarpa) in LPS (lipopolysaccharide)-stimulated RAW 264.7 murine macrophage cells. The results showed that Ame pre-treatment significantly ameliorated oxidative stress and inflammatory biomarker activities, as evidenced by reductions in the production of ROS (reactive oxygen specie), MDA (malondialdehyde), and NO (nitric oxide), as well as suppression of iNOS (inducible nitric oxide synthase), COX-2 (cyclooxygenase) and PGE2 (prostaglandin E2) mRNA levels; remarkably elevated the level of anti-inflammatory cytokine IL (interleukin)-10; and reduced the levels of the pro-inflammatory cytokines IL-1p, IL-6, and TNF-a (tumour necrosis factor). Additionally, we observed an attenuation of the cell apoptosis levels and the mRNA expression of apoptosis factors such as caspase-3 and caspase-9. In summary, the results highlight the health benefit of Ame against inflammation in LPS-stimulated RAW 264.7 cells.
Maternal and Fetal Outcomes in Pregnant Women with Major Degree Placenta Previa at ESIC MC and PGIMSR

Background and aim: Placenta previa describes a placenta implanted in lower uterine segment either on or very near the internal os (1:300 pregnancies). With an increasing rate of cesaerean section, the incidence of placenta previa and its complications are increasing. Hence, we undertook the present study with an aim to identify the risks factors and to study the maternal and fetal outcomes in major degree of placenta previa. Methods: A Prospective Observational studyJanuary 2019 to June 2020 at ESIC MC and PGIMSR, Rajajinagar, Bengaluru, in the Department of Obstetrics and Gynaecology. Demographic profile, risk factors, preoperative, intraoperative and postoperative maternal and fetal events were recorded. Results: Among 5000 deliveries, 37 women were diagnosed with placenta previa (0.74%). Median age 26years, multiparity [25,67%], previous cesarean section[14,37%], previous abortions[13,35%]. Major degree placenta previa (31,83%), antepartum hemorrhage (9,24%), anterior placenta previa (24, 64%). 24 (64%) underwent emergency cesaerean section with a mean estimated blood loss of 1500ml. Massive transfusions were done in 2(5.4%) women with adherent placenta. Haemostatic sutures were used in 32(86.5%) women. 2 (5.4 %) underwent cesarean hysterectomy. 3(8.1%) had a near miss and needed ICU care. Mean baby weight was 2500 grams ±400 grams. NICU admission 13(35.1 %) was prematurity. Neonatal mortality was 2(5.4%). Conclusion: Prudent decisions to reduce the scarring of uterus could prevent major degree of placenta previa. Institutional delivery where there is availability of skilled multispeciality team with robust blood bank facilities is the cornerstone to avert maternal and neonatal
Physicochemical Characteristics of Landfill Leachate from Simpang Renggam Landfill Site, Johor, Malaysia

The worldwide increasing amount of municipal solid waste causes a major problem in managing waste as well as requires an effective solution to manage the waste generation. In Malaysia, landfilling is the main alternative technique for managing solid waste. In the same way, the main advantage of having a landfill is that it is easy to operate and comparatively lower in cost. Thus, in Malaysia, total 296 municipal solid waste landfills are open to overcome this issue. Drawbacks of landfilling can includes; i) generation of noxious gases, ii) leachate wastewater contamination of both ground and surface water, iii) problems such as odor, noise, and dust, iv) attraction of disease vectors and, v) the requirement for considerable land area. This present research study focuses on the characterization of Simpang Renggam Landfill (SRLS) Site such as its organic constitutes (mg/L), Ammoniacal Nitrogen (mg/L), SS (mg/L), BOD5/COD, BOD5 (mg/L), and pH. All the analyzed results were compared with the past researchers’ researches and also were compared with Malaysian Environmental Quality Act 1974. From the results, it is concluded that the Simpang Renggam Landfill Site was characterized old (stabilized) landfill leachate wastewater with BOD5/COD > 0.1. For the SRL site, it is recommended that physical-chemical method is better fitted for the leachate wastewater treatment and the aerated lagoon technique does not support the treatment of aging leachate.
Orchiectomy Versus Goserelin Each Plus Bicalutamide in Patients with Metastatic Adenocarcinoma of the Prostate: Adverse Events Highlighted

Background: Androgen deprivation therapy (ADT), palliation for advanced/metastatic prostate cancer can be medical or surgical. This study compares the results of goserelin injection to orchiectomy each in combination with bicalutamide in patients diagnosed with metastatic adenocarcinoma of the prostate highlighting the adverse events. Methods: Ninety-six patients with histologically diagnosed adenocarcinoma of the prostate, were prospectively randomized into two arms. Medical arm patients had subcutaneous goserelin injection plus bicalutamide. Surgical arm patients had bilateral orchiectomy plus bicalutamide. A nadir serum prostate specific antigen (PSA) of 0.2ng/ml was chosen and response to treatment was by determining total serum PSA levels at 3 and 6 months. The student’s t test, chi-squared test and Kaplan-Meier survival analysis were the instruments for statistical analysis. Results: Follow up was between 6-30 months. There were 11 (23%) and 9 (19%) deaths in the surgical and medical arms respectively. At 6 months serum PSA levels of ≤ 0.2ng/ml was noted in 44 (92%) and 45 (94%) patients of the medical and surgical castrations respectively. Anemia, impotence, hot flushes were some of the adverse events noted in both groups during the study worse with medical castration. Conclusion: There was no statistical difference between the oncological efficacy and survival of both arms of treatment but a statistical difference in the adverse events