Factors associated with the use of gastrointestinal medicines amoung older people with intellectual disabilities in Ireland

(assess last) 1. Key information ❏ 2. Balanced ❏ and informative ❏ Text (assess last) 1. Sufficient detail others could reproduce ❏ 2. Clear/concise writing ❏, table(s) ❏, diagram(s) ❏, figure(s) ❏ Preliminaries [/5] 2. Introduction Background 1. Summary of current knowledge ❏ 2. Specific problem(s) addressed ❏ and reason(s) for addressing ❏ Objective 1. Primary objective(s), hypothesis(es), or aim(s) ❏ 2. Secondary question(s) ❏ Is it worth continuing? Introduction [/5] 3. Design Research design 1. Research design(s) chosen ❏ and why ❏ 2. Suitability of research design(s) ❏ Intervention, Treatment, Exposure 1. Intervention(s)/treatment(s)/exposure(s) chosen ❏ and why ❏ 2. Precise details of the intervention(s)/treatment(s)/exposure(s) ❏ for each group ❏ 3. Intervention(s)/treatment(s)/exposure(s) valid ❏ and reliable ❏ Outcome, Output, Predictor, Measure 1. Outcome(s)/output(s)/predictor(s)/measure(s) chosen ❏ and why ❏ 2. Clearly define outcome(s)/output(s)/predictor(s)/measure(s) ❏ 3. Outcome(s)/output(s)/predictor(s)/measure(s) valid ❏ and reliable ❏ Bias, etc 1. Potential bias ❏, confounding variables ❏, effect modifiers ❏, interactions ❏ 2. Sequence generation ❏, group allocation ❏, group balance ❏, and by whom ❏ 3. Equivalent treatment of participants/cases/groups ❏ Is it worth continuing? Design [/5] 4. Sampling Sampling method 1. Sampling method(s) chosen ❏ and why ❏ 2. Suitability of sampling method ❏ Sample size 1. Sample size ❏, how chosen ❏, and why ❏ 2. Suitability of sample size ❏ Sampling protocol 1. Target/actual/sample population(s): description ❏ and suitability ❏ 2. Participants/cases/groups: inclusion ❏ and exclusion ❏ criteria 3. Recruitment of participants/cases/groups ❏ Is it worth continuing? Sampling [/5] 5. Data collection Collection method 1. Collection method(s) chosen ❏ and why ❏ 2. Suitability of collection method(s) ❏ Collection protocol 1. Include date(s) ❏, location(s) ❏, setting(s) ❏, personnel ❏, materials ❏, processes ❏ 2. Method(s) to ensure/enhance quality of measurement/instrumentation ❏ 3. Manage non-participation ❏, withdrawal ❏, incomplete/lost data ❏ Is it worth continuing? Data collection [/5] 6. Ethical matters Participant ethics 1. Informed consent ❏, equity ❏ 2. Privacy ❏, confidentiality/anonymity ❏ Researcher ethics 1. Ethical approval ❏, funding ❏, conflict(s) of interest ❏ 2. Subjectivities ❏, relationship(s) with participants/cases ❏ Is it worth continuing? Ethical matters [/5] 7. Results Analysis, Integration, Interpretation method 1. A.I.I. method(s) for primary outcome(s)/output(s)/predictor(s) chosen ❏ and why ❏ 2. Additional A.I.I. methods (e.g. subgroup analysis) chosen ❏ and why ❏ 3. Suitability of analysis/integration/interpretation method(s) ❏ Essential analysis 1. Flow of participants/cases/groups through each stage of research ❏ 2. Demographic and other characteristics of participants/cases/groups ❏ 3. Analyse raw data ❏, response rate ❏, non-participation/withdrawal/incomplete/lost data ❏ Outcome, Output, Predictor analysis 1. Summary of results ❏ and precision ❏ for each outcome/output/predictor/measure 2. Consideration of benefits/harms ❏, unexpected results ❏, problems/failures ❏ 3. Description of outlying data (e.g. diverse cases, adverse effects, minor themes) ❏ Results [/5] 8. Discussion Interpretation 1. Interpretation of results in the context of current evidence ❏ and objectives ❏ 2. Draw inferences consistent with the strength of the data ❏ 3. Consideration of alternative explanations for observed results ❏ 4. Account for bias ❏, confounding/effect modifiers/interactions/imprecision ❏ Generalisation 1. Consideration of overall practical usefulness of the study ❏ 2. Description of generalisability (external validity) of the study ❏ Concluding remarks 1. Highlight study’s particular strengths ❏ 2. Suggest steps that may improve future results (e.g. limitations) ❏ 3. Suggest further studies ❏ Discussion [/5] 9. Total Total score 1. Add all scores for categories 1–8