Miracle-dz/UniFAR-FTUs huggingface dataset:
Quality of life among displaced Kashmiri pandit migrant adolescents

The migration of mass population within their own countries has become a serious problem worldwide because it affects the people, their livelihood and also results in cultural alienation and identity crisis. The Kashmiri Pandit community also faced forced migration from their home land to Jammu and other parts of India. In spite of more than two decades post their migration, many of these displaced community members continue to bear the brunt of it. The present study analysed the quality of life as perceived by adolescents belonging to Kashmiri pandit migrant families. The sample for the study comprised of 80 adolescent boys and girls selected by a combination of random and purposive sampling technique from Jagti, residential colony for kashmiri migrants on the outskirts of Jammu city. Interview schedule and Standardised Quality of Life Inventory was used for data collection. The results reveal that most of the sample adolescents scored high on various dimensions of quality of life. They showed high level of satisfaction with their health, self-esteem, goals and values, work, play, friendships, love, learning and creativity. Though on other components also most of them scored high yet many adolescents showed dissatisfaction with their monetary status, home, relationships, family and ability to help others. They held the belief that if their families had not migrated they would have been financially more stable and hence would have been able to afford most material goods. Both, boys as well as girls; as well as early and late adolescents held similar levels of satisfaction with various components of quality of life.
Ipsilateral Femoral Neck and Shaft Fractures

Ipsilateral fractures of the femoral neck and shaft are usually the result of high-energy trauma. The incidence ranges from 2.5-6% [13]. With improvements in trauma care the incidence will only increase as the mortality amongst multiple trauma patients decreases. The associated neck fracture is initially missed in up to 33% of cases [4,5]. These patients tend to have multisystem injuries as well as other associated orthopaedic injuries [2,6]. There is a 22.6% associated incidence of open fractures, while injuries involving the knee are seen quite commonly in up to 40 % of cases [5,6]. In managing these patients, the orthopaedic surgeon is confronted with a number of issues as it relates to the management of the multiple trauma patient: the timing of surgery and the subtle differences or additional challenges posed when a neck of femur fracture has an associated shaft fracture. A case is presented here to highlight these management dilemmas.
Clinical presentation of Dengue in a general hospital in Bangladesh

Dengue is one of the commonest viral diseases of Africa and tropical Asia. This disease is characterized by headache, fever, generalized body pain, severe malaise and back pain. The uncomplicated Dengue which is also named the classical dengue fever usually begins 3-8 days after biting of an infected mosquito. This is a cross sectional study on clinical presentation of Dengue in a general hospital in Bangladesh. The total number of patients was 198. The study period was 6 months (July 2004 to December 2004). All the patients who were admitted in the â€˜Dengue wardâ€™ and diagnosed as Dengue by serological test were included in this study. The aim of this study was to evaluate the common clinical presentations of Dengue in a General hospital in Bangladesh. The aim and objective was to compare the clinical presentations of Dengue in Bangladesh patients with those of other international studies. Most of the patients were male (3.7 :1) in sex and young adult(s) in age (80.3%). Fever and severe backache were the commonest clinical features. Nearly two-third (74%) patients presented with hemorrhagic features. Gum bleeding (20.2%) was the commonest bleeding feature. The result of this study showed a similarity with that of other international studies.
The Effect of Conservative versus Usual Intrapartum Fluid Management for Low Risk Women with Epidural Analgesia on Newborn Weight Loss in Breastfed Infants

The Effect of Conservative Versus Usual Intrapartum Fluid Management for Women with Epidural Analgesia on Newborn Weight Loss in Breastfed Infants The FILL Trial (Fluid in Low Risk Labour) There is uncertainty regarding how much intravenous fluid should be given to women in the intrapartum period. There are no published protocols or guidelines available to address fluid management in labour to optimize care for women and their infants. The absence of an evidencebased approach to intrapartum fluid management may result in fluid overload, with consequent maternal and newborn morbidity. The FILL Trial sought to answer the question, for low risk women receiving epidural analgesia in labour, ‘what is the effect of a conservative protocol for fluid management versus usual care on breastfed newborns’ weight loss prior to hospital discharge? The FILL Trial was a single site randomized controlled trial comparing a conservative protocol of fluid management with usual care for low risk women receiving epidural analgesia in labour. Women in the conservative care group received an IV volume prior to epidural analgesia initiation of < 500 ml and an IV infusion rate of 110 ml per hour. Women in the usual care group received an IV volume prior to epidural analgesia initiation of >500 ml and an IV infusion rate of 200 ml per hour. The primary outcome of interest was the proportion of breastfed infants who lost > 7% of their birth weight prior to discharge.
A systematic review of qualitative studies capturing the subjective experiences of Gay and Lesbian individuals’ of faith or religious affiliation

ABSTRACT Individuals identifying as religious tend to report better health and happiness regardless of affiliation, work and family social support or financial status. Evidence suggests that cultural factors are intertwined with these concepts. Exploration of sexual minorities' experiences has been neglected. Recently, a body of evidence is developing concerning this population, with theoretical speculation for changes of “stressors” for future generations and implications, particularly, on mental health. Lesbian and Gay (LG) individuals of faith (or spirituality) are susceptible to unique “stressors”; however, religion can provide a support network providing protective health benefits. This review systematically explores the existing evidence for the subjective experiences and accounts of LG people of faith. Sexual minority individuals who follow a religion or faith can experience good social support, reducing the risk of negative health outcomes, while for others, potentially serious, negative mental and physical health consequences are experienced (e.g., internalised homophobia, anxiety, rejection and suicidal ideation).
Subcortical magnocellular visual system facilities object recognition by processing topological property

The Magnocellular (M) visual pathway is known as a fast route to convey coarse information and facilitates object recognition by initiating top-down processes. It is unclear what exact properties M pathway conveys to accelerate visual object processing. Previous studies suggest that visual systems are highly sensitive to the perception of topological property (TP), which remains unchanged under various shape changes, and the TP is probably processed through a fast subcortical pathway. Here we hypothesize that a subcortical M system contributes to the fast object recognition by processing TP first. We first demonstrate that the facilitation effect of TP processing on object perception occurs mainly in the M visual system, and then support the subcortical M hypothesis of TP processing by the evidence that the early processing of TP was not affected when cortical function was temporarily damaged by the transcranial magnetic stimulation and when stimuli were biased to M system.
Analysis of Product Placement in Film-induced Tourism: Case Study of Summer Times

ABSTRACT The purpose of this research was to investigate the effects of film-induced tourism and analyze whether the audience would notice messages about tourist attractions and whether this information would affect the audience's intentions toward the tourist attractions. In the experiment, volunteers were asked to watch films with scenic spots, and questionnaires were given before and after the test. The structured questionnaire was designed to collect data on marketing strategy, attitude and travel intentions. The results show that attitudes and travel intentions toward scenic sites are affected by the exposure effects of scenic sites, strength of the link between scenic sites and plot, and the preferences shown through the roles and plot. Attitudes have significant influence on travel intentions. The results of this study show that films are a useful tool to promote tourism.
Fast decoding cell type–specific transcription factor binding landscape at single-nucleotide resolution

Decoding the cell type-specific transcription factor (TF) binding landscape at single-nucleotide resolution is crucial for understanding the regulatory mechanisms underlying many fundamental biological processes and human diseases. However, limits on time and resources restrict the high-resolution experimental measurements of TF binding profiles of all possible TF-cell type combinations. Previous computational approaches either can not distinguish the cell-context-dependent TF binding profiles across diverse cell types, or only provide a relatively low-resolution prediction. Here we present a novel deep learning approach, Leopard, for predicting TF-binding sites at single-nucleotide resolution, achieving the median area under receiver operating characteristic curve (AUROC) of 0.994. Our method substantially outperformed state-of-the-art methods Anchor and FactorNet, improving the performance by 19% and 27% respectively despite evaluated at a lower resolution. Meanwhile, by leveraging a many-to-many neural network architecture, Leopard features hundred-fold to thousand-fold speedup compared to current many-to-one machine learning methods.
TITLE: "Angiotensin-II Potentiates Alpha-Adrenergic Vasoconstriction in the Elderly" AUTHORS:

250 words) Aging is characterized by increased sympathoexcitation, expressed through both the alphaadrenergic and renin-angiotensin-aldosterone (RAAS) pathways. While the independent contribution of these two pathways to elevated vasoconstriction with age may be substantial, significant cross-talk exists that could produce potentiating effects. To examine this interaction, 14 subjects (n = 8 young, n = 6 old) underwent brachial artery catheterization for administration of angiotensin-II (ANG-II) (0.8-25.6 ng/dl/min), norepinephrine (NE) (2.5-80 ng/dl/min) and ANG-II with concomitant alpha-adrenergic antagonism (phentolamine (PHEN), 10 μg/dl/min). Ultrasound Doppler was utilized to determine blood flow, and therefore vasoconstriction, in both infused and contralateral (control) limbs. Arterial blood pressure was measured directly, and sympathetic nervous system activity was assessed via microneurography and plasma norepinephrine (NE) analysis. ANG-II sensitivity was significantly greater in the old, indicated by both greater maximal vasoconstriction (-59±4%, old vs. -48±3%, young) and a decreased half-maximal effective concentration (EC50) (1.4 ± 0.2 ng/dl/min, old vs. 2.6 ± 0.7 ng/dl/min, young), while the maximal NE-mediated vasoconstriction was similar between groups (-58±9% old, -62±5% young). ANG-II also increased venous NE in the old, but was unchanged in the young group. In the presence of alpha adrenergic blockade (PHEN), maximal ANG-II-mediated vasoconstriction in the old was restored to that of the young (-43±8% old, -39±6% young). These data indicate that with healthy aging, the increased ANG-II-mediated vasoconstriction may be attributed, in part, to potentiation of the alpha-adrenergic pathway, and suggest that cross-talk between the RAAS and adrenergic systems may be an important consideration in therapeutic strategies targeting these two pathways. Clinical Science Immediate Publication. Published on 18 Sep 2012 as manuscript CS20120424 T H IS IS N O T T H E V E R S IO N O F R E C O R D s ee d oi :1 0. 10 42 /C S 20 12 04 24 Ac ce pt ed M an us cr ip t Licenced copy. Copying is not permitted, except with prior permission and as allowed by law. © 2012 The Authors Journal compilation © 2012 Biochemical Society
Computational Mechanisms Underlying the Influence of Agency on Learning

We live in an uncertain environment where making flexible predictions about the occurrence of positive and negative events is necessary for maximizing rewards, minimizing punishments, and guiding future behavior. Predictions are most accurate, and feedback most useful, when our own actions are responsible for the outcomes we receive. Both humans and animals exhibit a bias toward presuming control, or agency, over outcomes (Mineka, 1985), and extensive work suggests that beliefs about agency have substantial effects on how individuals learn from different types of outcomes. By utilizing computational models, neuroimaging, and flexible behavioral tasks, this dissertation investigated the behavioral and neurobiological pathways through which humans make inferences about hidden information and determined how these inferences influence learning processes. We first found that inference about hidden agents modulated biased learning of positive and negative outcomes within the same individuals. A novel Bayesian model could account for this learning asymmetry, demonstrating a mechanistic framework for understanding how causal attributions contribute to learning (Paper 1). Next, we showed that RPE signals in the dorsal and ventral striatum were scaled by both subjective and model-derived beliefs about agency, but in opposite directions, providing preliminary evidence that striatal learning is gated by causal inference (Paper 2). Finally, we show that controllability arbitrates the use of a Pavlovian over an
Antioxidative properties and proximate analysis of spent coffee ground (SCG) extracted using ultrasonic-methanol assisted technique as a potential functional food ingredient

Spent coffee ground (SCG) produced in tons by restaurants and cafeterias and domestic consumers is a potentially good source of natural antioxidants because it contains substantial amounts of bioactive compounds. The purpose of this study was to identify the physicochemical and antioxidant properties of three different types of spent coffee ground (SCG), namely Robusta, Arabica and Liberica extracted using ultra-sonicmethanol assisted technique. DPPH, FTC, TBA, total phenolic content (TPC) and total flavonoid content (TFC) were used to measure the antioxidant properties. Robusta SCG exhibited the highest DPPH inhibition 41.63±0.04%), FTC (60.42±0.03%) and TBA analysis (73.09±0.08%). The total phenolic compounds in the samples varied widely ranging from 18.94±0.06 to 26.23±0.86 mg GAE/g sample, with Robusta SCG showing the highest value among the three, while Arabica SCG depicted the highest amount total flavonoid content (47.62±0.05 to 56.20±0.08). A strong correlation between antioxidant activity and total phenolic content were observed in this study. Compared to Arabica and Liberica SCGs expended, Robusta SCG demonstrated a stronger beneficial effect against lipid peroxidation. This study reveals that SCGs can be regarded as a new useful source of natural antioxidant with a view to increasing the use of antioxidant synthetics by using the ingredient of agro-industrial residues in food production especially ingredients for functional food.
Knowledge Sharing of Medical Practices—Reducing the Negative Socio-Economic Effects of Lead Exposure due to Unhealthy Consumption Habits

The emergence of knowledge economy has created the necessary conditions for an interdisciplinary approach of medical practices. This paper explores, in an interdisciplinary manner, the case of lead exposure in the Romanian context. We consider it crucial to be aware of the socio-economic impact of lead exposure in Romania and prevent unhealthy consumption habits that generate economic and social costs. The purpose of the research is to evaluate the social, economic, and medical effects of lead poisoning, and, on this basis, to identify prevention recommendations. The research was conducted while using a descriptive survey based on qualitative and quantitative methods, by analyzing a group of 115 participants that were admitted in the Toxicology Department of the Clinical Emergency Hospital Bucharest with the diagnosis of lead exposure/intoxication. The study followed an Observational Retrospective Protocol that was based on the investigations of the participants registered in the Toxicology Department with signs and symptoms suggestive of lead exposure/intoxication. The data was statistically processed by while using Microsoft Excel 2013 and SPSS Statistics 22. Based on our research results, we facilitated the knowledge sharing process of medical practices and formulated a series of recommendations in an interdisciplinary manner, in order to diminish the negative socio-economic effects of unhealthy consumption habits.
Neurotransmitters & networks: an MR view on epilepsy and antiepileptic drugs

The aim of this dissertation is to study the relationship between brain connectivity and cognitive problems resulting from epilepsy and antiepileptic drug use as well as the techniques used to examine this. Brain networks are studied by means of functional magnetic resonance imaging (fMRI). Neurotransmitters, which are important messengers that coordinate communication within the networks, are studied by means of magnetic resonance spectroscopy (MRS). It is shown that the neurotransmitter levels measured are associated with antiepileptic drug use and cognition. The best technique to measure these levels is assessed. In addition, a new analysis method for measuring brain networks is developed based on neurotransmitter levels measured by 7T MRI. These networks are shown to be abnormal in patients with epilepsy. The results of this dissertation contribute to a better understanding of cognitive side effects of antiepileptic drug use. They also provide information which can be helpful in further exploring this relationship, allowing treatment strategies for patients with epilepsy to be improved.
Southern Caspian Sea wind speed retrieval from C-band Sentinel-1A SAR images

ABSTRACT Synthetic aperture radar (SAR) imagery has shown the good capability for ocean wind speed retrieval. However, SAR wind speed retrieval above enclosed seas has been investigated rarely. In this study, the performance of geophysical model functions (GMFs) for the southern Caspian Sea wind speed retrieval from VV-polarized C-band Sentinel-1A SAR images is investigated. The used GMFs are recently developed empirical CMOD7 and C_SARMOD2, and two theoretical GMFs, which are derived in a simplified form based on the small-slope approximation (SSA) method with Hwang-Elfouhaily (H-E) and Hwang-McDaniel (H-M) composite sea spectra. Required wind directions for retrievals are obtained from wind streaks on SAR images by the local gradient (LG) method, a weather prediction model and in situ measurements. Estimations of all GMFs show good statistical agreements with predictions and in situ measurements. At 25-km resolution, all retrievals have mean biases better than ±0.7 m s−1, and root-mean-square deviations (RMSDs) and standard deviations below 2 m s−1 relative to predicted wind speeds. At 1-km resolution, using in situ measured directions, root-mean-square errors (RMSEs) of retrievals relative to in situ measured wind speeds are below 1.9 m s−1, and mean biases are better than ±0.7 m s−1. Of all the GMFs, CMOD7 has the best performance with the smallest RMSEs, and C_SARMOD2 has a good performance, except for very low winds. The theoretical GMF with H-M spectrum has a better performance than the model with H-E spectrum, and both of them can be used to retrieve Caspian Sea wind speeds from Sentinel-1A data, except for the crosswind condition with radar incident angle of about 45°.
A Physical Layer Security Technique for NOMA Systems with MIMO SC-FDE Schemes

Current wireless communication systems employ Multi-Input, Multi-Output (MIMO) techniques to increase spectral efficiency, at the cost of higher hardware complexity. Most of these systems continue to employ traditional Orthogonal Multiple Access (OMA) schemes, which are suboptimal when compared to Non-Orthogonal Multiple Access (NOMA) schemes. By combining NOMA with MIMO, it is possible to achieve higher spectral efficiencies. However, security in NOMA-MIMO systems remains a problem. In this paper, we study the physical layer security issues of a power based NOMA-MIMO system with a Singular Value Decomposition (SVD) scheme, employed along with Single Carrier with Frequency Domain Equalization (SC-FDE) techniques. We consider a scenario where there is an unintended eavesdropper attempting to listen to the messages being exchanged. It is shown that the higher the channel estimate correlation between transmitter and receiver, the higher the secrecy rate, particularly for a scenario where there is a Line-Of-Sight (LOS) between all users. Therefore, power based NOMA MIMO-SVD schemes, combined with SC-FDE, can be considered efficient options for highly secure MIMO communications.
Functional Outcome on Surgical Treatment For Lower Extrimity Tuberculosis Arthritis At Cipto Mangunkusumo Hospital Jakarta

Introduction: Osteoarticular tuberculosis more frequently occur on weight bearing joints. 1,8 On late stage tuberculosis osteoarthritis choices of surgical treatment involved synovectomy, osteotomy, arthrodesis, and arthroplasy 11 Results on functional outcome after surgery would be useful to decide appropriate treatments and prognosis. Method: This descriptive analytic study involved all lower extremity tuberculosis osteoarthritis that underwent surgical procedure at Cipto Mangunkusumo hospital in 5 years periods from 2008 to 2012. Follow up performed for minimal 6 months after surgery. Patients were evaluated using Lower Extremity Functional Score (LFES) and functional score according the joints involved, including Harris Hip Score (HHS), Knee Society Score (KSS), and Foot & Ankle Disability Index (FADI). Results: Study only involved late stage cases with average age at surgery was 30.04 (SD 16,67) years old. Average follow-up 33.68 months (SD 18.67). There are significant difference (p<0.001) of the LFES between preoperative (27.41), 6 months after surgery (42.19) and on last follow up (63.04). There were also difference (p<0.001) on Functional Score (HHS, KSS and FADI) preoperative (27.48), 6 months after surgery (60.11) and on last follow up (82.56). There is positive correlation between time of follow up and LEFS on last follow up. On last follow up, there is also significant difference of LEFS between groups that had arthrodesis and arthroplasty (p 0.045.) Conclusions: Results of surgical treatment gave significant improvement on functional outcome of the joint involved. The result however is correlated to the type of joints involved, type of surgery performed and the time after surgery.