Miracle-dz/UniFAR-FTUs huggingface dataset:
Prenosological screening of autonomic regulatory systems tension in secondary school students

Adolescence is characterized by increased reactivity to stress factors, among the sources of which the educational environment plays a significant role. The content of education and educational process organization, as well as interpersonal relationships, is the predominant stress factors of the educational environment. In the context of education reform, new pedagogical projects are being introduced, in particular, on the basis of meritocratic education, providing for the intensification of the educational process. It may affect the state of the autonomic regulatory systems of students. The purpose of the research is to study the activity level of autonomic regulatory systems among students of secondary school, who are studying in meritocratic and traditional gymnasium education systems. The study involved 60 students: 42 studied in meritocratic system (19 in SG-1, 23 in SG-2), and 18 in traditional system (SG-3). Heart rate variability (HRV) was used as a physiological marker of stress. ECG was recorded during 5 minutes in a darkened room in a rest state with closed eyes in a sitting position at the 5th, 6th and 7th grades. Intergroup comparisons of HRV parameters were carried out according to the Mann-Whitney, Kruskell-Wallis, Dunnett criteria, and the φ-criterion of the angular Fisher transformation. Differences were considered significant at р≤0.05. In the 6th grade, there was a tendency (0.05<р≤0.07) to lower values of Mean, SDNN, TR, ΔX, RMSSD, pNN50 among students in meritocratic system compared to the traditional one. However, this trend reached the level of statistical significance in the students of SG-1 compared to the control (SG-3). In meritocratic education different student groups differed in the level of school stress in 6th and 7th grades. Students in SG-1, compared to SG-2, characterized by lower values % HF, HFn, pNN50 against the background of higher values of % LF, LFn, LF/HF, IC, CC1, CC0. Thus, a higher level of school-based stress in conditions of meritocratic education is determined not so much by the intensification of the educational process as by social factors of the educational environment and/or individual typological traits of students.
GENDER-BASED VIOLENCE AND SOCIO-ECONOMIC DEVELOPMENT IN LAGOS STATE, NIGERIA

Gender based violence in Nigeria has been a pervasive quagmire which has attracted both government and non-governmental organizations. This menace apparently is not limited to women as they affect both genders. Nonetheless, women more often than not are usually at the receiving end of violence which consequently reinforces existing gender inequalities that have unfortunately affected the nation’s socio-economic apparatus. Pathetically, this vice remains a challenge that significantly limits women’s auton­omy, opportunities and predisposes them to poverty . Sexual and physical violence as well as early child marriage are challenges that have not been effectively addressed by governmental agencies hence the reason for this research study. Primary and secondary data were adopted and the findings from this paper revealed that domestic violence has affected the career advancement of women. More worrisome is the fact that government agencies have not been able to find a sustainable solution to the menace. The study therefore concludes and recommends that the destructive culture of child marriage must be eradicated if women are to advance in their careers and maximally contribute to the development of the society and this can be achieved through public enlightenment at the grassroots’ level on the implication of child marriage.
THEORETICAL MODELING OF DEFECTS IN THE MOLECULAR CRYSTAL OF 2-(2'-HYDROXYPHENYL)BENZOTHIAZOLE

2-(2'-hydroxyphenyl)benzothiazole is a photoreactive compound that exhibits excited state intramolecular proton transfer in the structure with an OH.N hydrogen bond. Energy of various structures is calculated for isolated molecules, clusters and periodic structures of 2-(2'hydroxyphenyl)benzothiazole by density-functional based tight-binding methods. It is shown that the most stable conformation of the isolated molecule is a planar structure with an OH.N hydrogen bond. Other conformations have significantly larger energy in comparison with the average room temperature heat energy that implies a low equilibrium number of those structures in non-polar solvents. In crystal the defect with lowest energy is non-hydrogen-bonded conformation formed by rotation of the OH bond. The energy of this defect is close to the energy difference for corresponding conformations of the isolated molecule. For other conformations, the energy values of the defects are larger than the energy differences for isolated molecules. In contrast to the crystal of 2-(2'-hydroxyphenyl)benzoxazole, energy of the defect caused by the entire molecule reorientation is comparable with the energy of defects caused by different conformations.
Utilization and Associated Factors of Emergency Contraception among Female College Students in Addis Ababa, Ethiopia

Background: Increasing the access and availability of modern contraceptives with emergency contraceptives prevent unplanned pregnancy. In Ethiopia, the rate of unintended pregnancy is high among adolescents. The role of the Emergency contraceptive is confirming in the prevention of unplanned pregnancy and its sequels. However, the use of emergency contraceptives in cities like Addis Ababa is verylow. Given that unsafe abortion is the leading cause of maternal mortality, appropriate use of emergency contraceptives as back up for regular contraceptive is therefore needed. Objective: This study has assessed the practice of emergency contraception and associated factors among female students in ALKAN Health Science Business and Technology (HSBT) College, Addis Ababa, Ethiopia. Methods: An institution-based study among 271 female ALKAN Health Science Business Technology College, Addis Ababa campus students using a self-administered questionnaire. The study subjects were selected randomly using a stratified sampling technique. We used both descriptive summaries statistics and logistic regression to present the study findings. Results: The majority (93.3%) had emergency contraceptives awareness. Among those who had heard about an emergency contraceptive, 81.5% had good emergency contraceptive knowledge. The magnitude of participants who had used emergency contraceptive was 12.9%, where oral pills (93.3%) were the most frequently used method. Factors significantly associated with the use of emergency contraception were user being sexually active [AOR=124.0, 95%CI=33.4-61.1)], age less than or equal to 20 years [AOR=5.7, 95%CI=2.35-3.91)], and being single [AOR=6.2, 95%CI= 1.91-20.0)]. Conclusion: Efforts should be made to educate college female students on emergency contraceptives usage in their formal lesson.
MARK-UP VS. INTEREST-BASED FINANCING ON GDP: AN APPLICATION OF AGENT-BASED COMPUTATIONAL MODEL

This study aims to introduce the application of artificial intelligence in the area of Islamic finance by examining the dynamic changes of gross domestic product (GDP) under fully markup-based financing. The application of artificial intelligence using agent-based computational model (ABM) is employed to conduct the simulation. The simulation result shows that the movement of GDP under markup-based financing which represents Islamic financial system has better performance compared to interestbased lending. In this regard, profit shared to depositors has positive impact on GDP which also proofs that Islamic banking system may promote sustainable economic growth and may create wealth for the whole society. This study proofs that Islamic bank essentially more stable than conventional bank and hence may fights against crisis. This study is potentially the initial work to examine the dynamic changes of economic growth under fully Islamic financial system by applying artificial intelligence concept as its methodology. Thus, this study is expected to contribute to the development of Islamic economics and finance research. Article history: Received : October 8, 2021 Revised : February 2, 2021 Accepted : February 19, 2021 Available online : February 28, 2021 https://doi.org/10.21098/jimf.v7i1. 1345 1 The corresponding author would like to thank LPDP (Lembaga Pengelola Dana Pendidikan), Ministry of Finance, Republic of Indonesia, for the award of a research endowment. In addition, the authors would like to thank the reviewers for their instructive comments and to thank Rema Prostinaldo Yunanto for his assistantship to this project. 1 Department of Economics, Universitas Gadjah Mada, Indonesia, diyah.putriani@ugm.ac. id 2 Department of Economics, International Islamic University Malaysia, Malaysia, gairuzazm@iium.edu. my 3 Department of Informatics System, International Islamic University Malaysia, Malaysia, mira@iium.edu. my
A Survey of Default Risk Methodologies for Equity Pricing with a Focus on Advances in the Field of Default Risk Assessment and Equity Pricing in Pakistan

The aim of this study is to review the default risk modelling literature from the perspective of Pakistan, where an effort has been put to cover the three classes of such models i.e. Accounting, Structural and Logit based hazard models. As per review it is very clear that the first two modelling techniques are extensively employed in Pakistan with Z-Score and KMV Merton model as commonly used estimation technique. Hazard models are the least used due to data issues, as for majority of delisted firms’ data is not available in data services like Thomson Reuters Eikon and Bloomberg before 2000 and even local data sources like Pakistan Stock Exchange is not of much help. Due to the reason Hazard Models are least employed for default risk estimation in Pakistan along with neural network models being most neglected one with only one paper in 2020. The review helps in identifying the gaps in this area of study, which include identification of models for future research and data issues in Pakistan along with equity pricing implications.
A randomized clinical trial on improving osteopenia in postmenopausal women after two years of preventive treatment with alendronate; a dose of 35 mg per week is more effective or a dose of 70 mg?

Introduction: Osteoporosis is the most common metabolic bone disease worldwide. In this disease, the bone mass decreases and as it progresses, the risk of fracture increases. Osteopenia occurs in the early stages of bone loss. Studies on the effective dose for treatment of osteopenia have been controversial. Objectives: In this randomized clinical trial, low doses versus high doses of alendronate were assessed during the osteopenic stage in postmenopausal women. Patients and Methods: The present study is a randomized clinical trial (RCT) that was performed on 152 postmenopausal women who were visited in Al-Zahra rheumatology clinic between 2016 and 2017. Patients were randomly divided into two groups. The first group with 35 and the second group with 70 mg of weekly alendronate were treated and followed for two years. Densitometry was performed on patients before and 2 years after the intervention, and the findings were compared. Results: The two groups were not significantly different in terms of age, gender, height, weight, body mass index (BMI) and menopause (P>0.05). The bone mineral density (BMD) findings of both groups, including Fracture Risk Assessment Tool (FRAX) hip and vertebra/wrist, T-score hip and vertebrae, as well as Z-score hip and vertebrae, improved significantly after two years (P<0.001), However, a comparison of the two therapeutic doses did not show a significant difference in terms of BMD improvements (P>0.05). Conclusion: The findings of this study reported favorable results for the preventive treatment of alendronate in osteopenic women. In addition, due to gastrointestinal problems that are the main complaint of alendronate use, according to the results, a weekly dose of 35 mg can be recommended
PRODUCTION OF HYDROLYZED BOVINE COLLAGEN WITH ORANGE JUICE CONCENTRATE

ydrolyzed bovine collagen is a polypeptide composite made by further hydrolysis of denatured collagen or gelatin. The results indicated that molecular weights are within the range approximately 500 to 25000 Da. In hydrolysate, the molecular mass and the size of the molecules have been deliberately decreased by partially hydrolyzing the peptide bonds of the gelatin molecules. This will increase the hydrolyzed collagen dissolvable in cold water and does not gel anymore. The processes involved in processing hydrolyzed collagen are demineralization, extraction of gelatin from collagen, enzymatic hydrolysis to obtain hydrolyzed collagen, ion exchange, filtration, evaporation, sterilization and finally spray drying. In previous study a large number of studies focused on the enzymatic hydrolysis of collagen or gelatin for the production of bioactive peptide. This study aims to produce hydrolyzed bovine collagen with concentrate orange juice from low bloom gelatin which considered byproduct in gelatin manufacturing to be food supplement for arthritis. The result indicated that adding concentrated orange juice during producing of hydrolyzed collagen increased the nutritional value of collagen especially in vitamin C from 0 mg/100g. to 500 mg/100g. While protein content decreased from 91% to 88%. For sensory evaluation it was found that overall acceptability for hydrolyzed collagen with orange juice was higher than hydrolyzed collagen without adding orange juice 8.37 and 6.31 respectively. Amino acid profile showed that the hydrolyzed collagen was high in glycine content 339.6 mol/1000 mol and the Proline and Hydroxyproline were 103.6 and 80.7 mol/1000 mol respectively, this means that the Proline and Hydroxyproline percent were almost 18.4 % which are important for producing glucosamine in the human body in presence of ascorbic acid
Application of Bacteriophage - Derived Endolysins as Potent Biocontrol Agents for Enhancing Food Safety

Endolysins, bacteriophage-encoded catalysts, have arisen as antibacterial specialists that can be effectively applied in food handling frameworks as food additives to control microorganisms and eventually improve sanitation. Endolysins separate bacterial peptidoglycan structures at the terminal advance of the phage generation cycle to empower phage offspring discharge. Specifically, endolysin treatment is a novel system for controlling anti-toxin safe microorganisms, which are an extreme and progressively continuous issue in the food business. What's more, endolysins can take out biofilms on the surfaces of utensils. Besides, the cell divider restricting area of endolysins can be utilized as an apparatus for quickly recognizing microorganisms. Exploration to expand the utilization of endolysins toward Gram-negative microbes is presently being broadly led. This survey sums up the patterns in endolysin research until this point and examines the future uses of these proteins as novel food safeguarding instruments in the field of sanitation.
Genetic Variability in Yield and Its Attributes of some Peanut (Arachis hypogaea L.) Genotypes under Different Water Regimes

The objective of this study was to investigate the response of advanced peanut breeding lines to water stress to identify the tolerant genotypes and the drought tolerance related traits besides to assess the genetic variability between genotypes under drought stress. Thus, two field experiments were conducted during the two successive seasons 2018 and 2019, in the Agricultural Research Station, Ismailia Governorate. Assessment of ten genotypes and three water regimes was done in a randomized complete block design with three replications. The water regimes were a full irrigation 100% w as a control, 75% w and 50% w stress irrigation. The results indicated existence of moderate genetic variability accompanied with high heritability and high GAM among the studied traits; days to maturity, shelling %, pod yield/plant, seed yield/plant and oil content under stress conditions. Also, the results indicated significant differences among the tested genotypes for all the investigated traits. Yield and its attributes of all genotypes varied under water stress and significant responses were observed. The genotypes No. 5, 6 and 3, showed the highest values for most of the yield and its attributes under the different water regimes. So, these genotypes are considered promising in peanut improvement program to produce drought tolerant varieties of peanut characterized with high yielding ability.
Preprint Title Development of QSAR ensemble models for predicting the PAMPA Effective Permeability of new, non-peptidic leads with potential antiviral activity against the coronavirus SARS-CoV-2. Authors

From the onset of the pandemic caused by the virus SARS-CoV-2, the scientific community responded– with a sense of urgency – by intensifying efforts to provide drugs effective against the disease COVID-19. To strengthen this efforts, a consortium of researchers initiated in March 2020 the “COVID Moonshot project” that has been accepting public suggestions for computationally triaged, synthesized, and tested molecules, with experimental data made publicly available. The main goal of the project was to identify through Fragment Based Drug Design (FBDD) small molecules with activity against the virus, for oral treatment. Since orally administered drugs are introduced to the bloodstream through absorption via the small intestine pathway, the ability of a drug to readily cross the intestinal cell membranes and enter circulation is decisively influencing its bioavailability. This explains the need to evaluate and optimize a drug’s membrane permeability in the early stages of drug discovery to avoid failures in latestage drug development owing to incomplete absorption and poor bioavailability. In our present
Effect of Financial Liberalization on Savings and Investment in Nigeria

In Nigeria, measures were taking by government between the period 1986 to 2005 to liberalise the financial sector as part of the overall structural adjustment programme (SAP) with the aim to promote economic growth and alleviate poverty. The financial reform assumes that deregulating the financial market will eliminate the distortion and fragmentation of the financial market. It will also improve the mobilisation of savings as well as efficiency in allocation of funds to viable investment projects in the economy. This in turn will help in accelerating economic growth. Literature in the area posits that liberalising interest rate and deepening of the financial market is growth enhancing. This hypothesis is tested by identifying two basics channel through which financial liberalisation is operational – savings and investment, and allocative efficiency. The analysis was carried out using macro data from Nigeria by employing Two-Stage-Least Square (2SLS) instrumental variable technique to analyse the data. Major findings pointed out that interest rate as determinant of savings is not statistically significant, and rising interest rate negatively affect investment growth. Secondly, investment follows the standard accelerator theory. Furthermore, growth in the stock of money is positively related with investment but statistically insignificant. Lastly, there is a considerable deepening in the banking sector, however, the capital market does not
Assessment of mental loop using cone beam computed tomography in a sample of Egyptians

ABSTRACT Introduction: Although the inferior alveolar nerve had been described as a single entity that travels through the mandibular canal and leaves it through the mental foramen directly giving rise to mental nerve, presence of mental loop was reported. Improper identification of mental loop led to increasing the incidence of nerve injury during surgical procedures especially implant placement. Objective of the study: The purpose of this study was to assess mental loop and its length among a sample of Egyptians, using cone beam computed tomography (CBCT). Materials and Methods: Two hundred and sixty-seven CBCTs were collected in which one hundred were males and one hundred and sixty-seven were females, then evaluated for the presence of the mental loop. The length of the loop was measured on reconstructed panoramic views of CBCT using on demand software. Results: Mental loop was present in one hundred and nine patients (40% of the patients), 63 females and 46 males. The minimum length observed was 2.27 mm. while the maximum length was 7.18mm and the mean length was 4.36±. 96mm. There was no significant difference between males and females. Conclusions: High prevalence of mental loop was detected in Egyptians. Based on this finding proper identification of mental loop by the method explained in this study prior to surgical planning is essential. Keywords: Anatomical variant, CBCT, inferior alveolar canal, mental nerve loop
The characteristics associated with alcohol co-ingestion in patients visited to the emergency department with deliberate self-poisoning: retrospective study

*Correspondence ewhain78@gmail.com (Duk Hee Lee) Abstract Objective: The aim of this study was to investigate the characteristics associated with alcohol co-ingestion by measuring blood alcohol concentration in patients visited to the emergency department with deliberate self-poisoning. Also, it was to evaluate the accuracy of self-reported alcohol ingestion. Methods: The initial assessment forms, medical records and laboratory tests of patients visited to the ED after DSP between March 2017 and June 2020 were retrospectively reviewed. Based on the patients’ BAC, two groups were formed: the non-alcohol group and the alcohol group. Results: This study included 286 patients (56.6%, n = 162) in the non-alcohol group and 43.4% (n = 124) in the alcohol group. In multivariate logistic analysis, alcohol coingestion was independently associated with no history of psychiatric admission (Odds Ratio = 6.222, 95% Confidence Interval = 1.148-33.716, P = 0.034), lactate (mg/dL) (Odds Ratio = 1.961, 95%Confidence Interval = 1.274-3.019, P = 0.002), and C-reactive protein level (mg/dL) (Odds Ratio = 0.003, 95% Confidence Interval = 0.000-0.897, P = 0.046). The receiver operating characteristics analysis of lactate value for the association with alcohol co-ingestion showed a cutoff value of 1.45, with 88.1% sensitivity, 71.6% specificity, and an area under the curve of 0.845. There was no statistically significant difference in emergency department disposition between the two groups. Using the 261 subjects who completed the self-report of alcohol co-ingestion, self-report resulted in 77.6% sensitivity and 76.6% specificity for the assessment of alcohol co-ingestion. The positive and negative predictive values for self-reporting were 72.6% and 81.0%, respectively. Conclusions: Alcohol co-ingestion was associated with no history of psychiatric ward admission, high lactate levels, and low C-reactive protein values in patients who visited the emergency department with deliberate self-poisoning. This study showed that selfreported alcohol co-ingestion was not a substitute for the blood alcohol concentration test.