Miracle-dz/UniFAR-FTUs huggingface dataset:
Mathematical modelling and optimization of the granulation process of loose compound feed for broilers

The article presents the results of studying the indicators of the crumbling of granules and the specific energy costs of experimental batches of granulated feed for broilers. The process of granulation of compound feed for broilers was studied using the statistical planning method of a multifactorial experiment using a granulation line, including a granulator press. The dependence of the crumbling of granules and the energy consumed on the selected factors has been established. The moisture content of the feed mixture W (%) and steam pressure P (MPa) were chosen to optimise the granulation process. A matrix plan of the experiment was compiled. With the optimal values of the factors obtained in the study using the experimental planning method, an experimental batch of granulated feed was developed. At the selected levels of factors, the calculated value of the crumbling of granules was 20.11%, which fits into the optimum according to the standard of the crumbling of granulated feed for poultry (no more than 22%). The specific electricity consumption was 9.23 kWh/ton. Experiments have shown that the discrepancies between the experimental and calculated data are insignificant and within these indicators' experimental error determination. Mathematical modelling of the granulation process of loose compound feed for broilers made it possible to solve an important practical problem – to optimize the granulation mode, which ensures the production of good quality granules with minimal energy consumption. The obtained optimal granulation parameters can serve as the basis for producing granulated feed for broilers.
A Receptor Integrin β1 Promotes Infection of Avian Metapneumovirus Subgroup C by Recognizing a Viral Fusion Protein RSD Motif

Avian metapneumovirus subgroup C (aMPV/C) causes respiratory diseases and egg dropping in chickens and turkeys, resulting in severe economic losses to the poultry industry worldwide. Integrin β1 (ITGB1), a transmembrane cell adhesion molecule, is present in various cells and mediates numerous viral infections. Herein, we demonstrate that ITGB1 is essential for aMPV/C infection in cultured DF-1 cells, as evidenced by the inhibition of viral binding by EDTA blockade, Arg-Ser-Asp (RSD) peptide, monoclonal antibody against ITGB1, and ITGB1 short interfering (si) RNA knockdown in cultured DF-1 cells. Simulation of the binding process between the aMPV/C fusion (F) protein and avian-derived ITGB1 using molecular dynamics showed that ITGB1 may be a host factor benefiting aMPV/C attachment or internalization. The transient expression of avian ITGB1-rendered porcine and feline non-permissive cells (DQ cells and CRFK cells, respectively) is susceptible to aMPV/C infection. Kinetic replication of aMPV/C in siRNA-knockdown cells revealed that ITGB1 plays an important role in aMPV/C infection at the early stage (attachment and internalization). aMPV/C was also able to efficiently infect human non-small cell lung cancer (A549) cells. This may be a consequence of the similar structures of both metapneumovirus F protein-specific motifs (RSD for aMPV/C and RGD for human metapneumovirus) recognized by ITGB1. Overexpression of avian-derived ITGB1 and human-derived ITGB1 in A549 cells enhanced aMPV/C infectivity. Taken together, this study demonstrated that ITGB1 acts as an essential receptor for aMPV/C attachment and internalization into host cells, facilitating aMPV/C infection.
Multi-Objective Security Constrained Unit Commitment via Hybrid Evolutionary Algorithms

This paper addresses the challenging problem of Unit Commitment (UC), which involves the optimal scheduling of power generation units while adhering to numerous network operational constraints called security-constrained UC (SCUC). SCUC problem aims to minimize costs subject to turning on economically efficient generators and turning off expensive ones. These operational constraints include load balancing, voltage level at buses, minimum up and down time requirements, spinning reserve, and ramp up and down constraints. The SCUC problem, subject to these operational constraints, is a complex mixed-integer nonlinear problem (MINLP). There has been a growing interest in using evolutionary algorithms (EAs) to tackle large-scale multi-objective MINLP problems in recent two decades. This paper introduces a novel approach to address the SCUC problem, which is further complicated by including network constraints. They are pioneering the integration of single and multi-objective EAs to solve the SCUC problem while incorporating AC network constraints through hybrid binary and real coded operators. The development of an ensemble algorithm that combines mixed real and binary coded operators, extended by a bidirectional coevolutionary algorithm to tackle multi-objective SCUC problems. The paper implements a new formulation based on three conflicting objective functions: cost of energy supplied, startup and shutdown costs of generators, energy loss, and voltage deviation to solve the SCUC problem. Implementing a new formulation also addresses the solution of single and multi-objective SCUC problems using a combination of proposed technical and economic objective functions. The proposed algorithm is rigorously tested on a 10-unit IEEE RTS system and a 6-unit IEEE 30-bus test system, both with and without security constraints, addressing week-ahead and day-ahead SCUC scenarios. Simulation results show that the proposed algorithm finds near-global optimal solutions compared to other state-of-the-art EAs. Additionally, the research demonstrates the effectiveness of the proposed search operator by integrating it with a multi-objective coevolutionary algorithm driven by both feasible and infeasible solutions, showcasing superior performance in solving multi-objective SCUC problems. These results are compared with various recently implemented Multi-Objective Evolutionary Algorithms (MOEAs), demonstrating the superiority of
Earnings Management- An Indian Perspective

Earnings on the board have been a gigantic and predictable issue among controllers and experts and have pick up critical consideration in the field of bookkeeping. This study focuses on Earnings Management in India. Subsequently, it tends to be inferred that at the time of the investigation, the Companies in the sample and since they are representative, the companies in India are indeed exhibiting Earnings Management Practices. There is additionally solid proof that various companies from various industry segments were bound to practice Earnings Management. The aftereffects of the study are in line with the findings of Nelson et al. (2002). This study has both academic and industry implications as this is forming base for further research in academics and the Industry practioners can have a fair idea of the Earnings management influencing parameters. The limitations of the study can be how representative the sample is and this is overcome by the fact that the samples were chosen in a random manner. Further studies can be conducted on the other financial parameters influencing Earnings management in the Indian context.
Update on Urinary Tract Infection Antibiotic Resistance—A Retrospective Study in Females in Conjunction with Clinical Data

Urinary tract infections (UTIs) represent a frequent pathology among the female population that has become more and more difficult to treat in the past decade, considering the increase in antibiotic resistance—a serious global public health problem. A cross-sectional retrospective study was conducted for six months to report an update regarding the rates of resistance and susceptibility of uropathogens necessary for optimal treatment. A total of 5487 patients were screened, of which 524 (9.54%) were female patients who met the criteria for inclusion in the study. Escherichia coli was the most common pathogen, representing 290 cases (55.34%), followed by Enterococcus spp. 82 (15.64%). Escherichia coli presented the highest resistance to amoxicillin-clavulanic acid (R = 33.1%), followed by trimethoprim-sulfamethoxazole (R = 32.41%) and levofloxacin (R = 32.06%). The highest sensitivity rates were observed for fosfomycin (S = 96.55%), followed by imipenem (S = 93.1%). Enterococcus spp. showed the highest resistance to levofloxacin (R = 50.0%), followed by penicillin (R = 39.02%). The highest sensitivity was observed for fosfomycin (S = 90.24%), linezolid (S = 89.02%), and nitrofurantoin (S = 86.58%). The second most frequent Gram-negative uropathogen was represented by Klebsiella spp. , which had the highest resistance to amoxicillin-clavulanic acid (R = 35.89%), followed by levofloxacin (R = 25.64) and trimethoprim-suflamethoxazole (R = 24.35%). The most frequently associated pathology was an episode of UTI in the previous year, followed by diabetes and chronic kidney disease. Antibiotic resistance is a serious problem for all clinicians who treat UTIs. An up-to-date knowledge of antibiotic resistance rates is a major necessity to stop its evolution. Overall, the highest resistance rates were observed for aminopenicillins, fluoroquinolones, and trimethoprim-sulfamethoxazole. The best susceptibility rates were observed for fosfomycin, nitrofurantoin, and carbapenems. Our report aims to guide clinicians whenever they are forced to prescribe antibiotics empirically.
Intra-articular Injection Therapy in Knee Osteoarthropathy: a Narrative Review

Knee osteoarthropathy is a common degenerative joint disorder that can cause pain and functional impairment in affected individuals. Various intra-articular injection therapies have been explored as potential treatments for knee osteoarthropathy, including corticosteroid, hyaluronic acid, dextrose and platelet-rich plasma. Intra-articular corticosteroid injection is commonly used for short-term pain relief. Patients with higher baseline pain level and milder changes of degeneration on imaging may bene ﬁ t more from corticosteroid injection. However, excessive use may lead to detrimental effects on joint tissues. Intra-articular hyaluronic acid injections have demonstrated positive effects in improving pain and function, as well as delaying the need for total knee replacement. The effects can be sustained for an extended period. Hypertonic dextrose injections may promote tissue repair and improve symptoms, but more research is needed to validate their ef ﬁ cacy. Platelet-rich plasma shows potential tissue growth-promoting effects. However, con ﬂ icting study results exist, and current clinical guidelines do not recommend its use due to limited evidence. When performing intra-articular injection, ultrasound-guided techniques have emerged as a superior alternative to landmark-guided methods, with improved accuracy, better clinical outcomes and potential cost-effectiveness.
A Supply Chain View of Product Carbon Footprints: Results from the Banana Supply Chain

Interest in the use of Life Cycle Assessment (LCA) to measure the carbon footprint of products has increased in recent years. While issues have been raised regarding the use of LCA to measure carbon footprints, the difficulties of doing so in the context of a modern supply chain have received less attention. In this paper we present a case study of the carbon footprint of bananas done in partnership with a leading importer of bananas and a U.S. retail grocery chain. Issues related to data quality and access represent a significant hurdle in measuring the carbon footprint across a supply chain, and we analyze our results in the context of ownership of the supply chain through the use of the GHG Protocol’s concept of emission scopes. Sharing information between supply chain partners has been promoted as one method of resolving data issues, but raises important issues related to supply chain variability. Through an analysis of the impact of transportation we show how the structure of a supply chain introduces significant variability in the carbon footprint required to serve different customers. ∗To whom correspondence should be addressed
MicroRNA Expression Profiling—Potential Molecular Discrimination of Papillary Thyroid Carcinoma Subtypes

Recent research has revealed the importance of miRNAs in the diagnosis and clinical evolution of papillary thyroid cancer (PTC). We aim to identify a specific miRNA profile that could differentiate between specific subtypes of PTC. Methods: In this cross-sectional study, total RNA was extracted from paraffin-embedded tissues of 43 patients, 17 with an infiltrative follicular variant of PTC (iFVPTC) and 26 with a conventional variant of PTC (cPTC). Nine miRNAs were evaluated using qRT-PCR technology and specific miRNA assays. Results: We found specific patterns for cPTC and iFVPTC, such as miRNA altered in both types of tumours (miR-146b-5p, miR-181a-5p, miR-221-3p, miR-21-5p and miR-222-3p) and two miRNAs significantly expressed only in cPTC (miR-20b-5p, miR-21-5p). The iFVPTC group presented strong and moderate correlations between miRNA expression and clinical data. miR-221-3p, miR-195-5p, miR-181-5p, miR-146b-5p and miR-222 were correlated with age, tumour size (TS) or lymph node metastases (N), while only miR-20b-5p, miR-195-5p and miR-181-5p were correlated with TS, N and age in the cPTC group. Conclusions: The present study allowed the identification of a signature of two miRNAs to confirm miRNA differences between the two histological subtypes of TC. Our results provide advances in the molecular diagnosis of TC and could help to improve the diagnostic performance of already existing molecular classifiers.
Kuala Lumpur As An Islamic City Tourism Destination: The Influence of Place Attractiveness and Experience Quality on Place Attachment

Global Islamic tourism is experiencing considerable expansion due to the growing Muslim population. This study specifically addresses the issue of how to build a strong emotional attachment to Kuala Lumpur to ensure that Kuala Lumpur consistently remains the destination of choice among Muslim tourists. This article begins with a systematic review, synthesis, and integration of existing knowledge on the role of place attachment and its theoretical background, emphasising the importance of psychological processes in explaining the relationship between place attractiveness, experience quality and place attachment. This research contributes to knowledge theoretically by arguing that the fusion of Islamic and conventional tourism and the quality of experience in the context of Islamic urban tourism could enhance visitors' emotional attachment. The framework can also serve to stimulate new research can help destination managers address the key conventional issue of Malaysia's long-term competitiveness or sustainability in the Islamic tourism market in general, or Kuala Lumpur in particular, in the Asia-Pacific region.
Remarks on the global regularity and time decay of the 2D MHD equations with partial dissipation

This paper focuses on a system of the two‐dimensional (2D) magnetohydrodynamic (MHD) equations with the partial kinematic dissipation (∂yyu1,∂xxu2) and the partial magnetic diffusion (∂yyb1,∂xxb2). Based on the basic energy estimates only, we are able to show that this system always possesses a unique global smooth solution when the initial data are sufficiently smooth. Moreover, we obtain optimal large‐time decay rates of both solutions and their higher order derivatives by developing the classic Fourier splitting methods together with the auxiliary decay estimates of the first derivative of solutions and induction technique.
A new perspective on the taxonomy and systematics of Arvicolinae (Gray, 1821) and a new time-calibrated phylogeny for the clade

Background Arvicoline rodents are one of the most speciose and rapidly evolving mammalian lineages. Fossil arvicolines are also among the most common vertebrate fossils found in sites of Pliocene and Pleistocene age in Eurasia and North America. However, there is no taxonomically robust, well-supported, time-calibrated phylogeny for the group. Methods Here we present well-supported hypotheses of arvicoline rodent systematics using maximum likelihood and Bayesian inference of DNA sequences of two mitochondrial genes and three nuclear genes representing 146 (82% coverage) species and 100% of currently recognized arvicoline genera. We elucidate well-supported major clades, reviewed the relationships and taxonomy of many species and genera, and critically compared our resulting molecular phylogenetic hypotheses to previously published hypotheses. We also used five fossil calibrations to generate a time-calibrated phylogeny of Arvicolinae that permitted some reconciliation between paleontological and neontological data. Results Our results are largely congruent with previous molecular phylogenies, but we increased the support in many regions of the arvicoline tree that were previously poorly-sampled. Our sampling resulted in a better understanding of relationships within Clethrionomyini, the early-diverging position and close relationship of true lemmings (Lemmus and Myopus) and bog lemmings (Synaptomys), and provided support for recent taxonomic changes within Microtini. Our results indicate an origin of ∼6.4 Ma for crown arvicoline rodents. These results have major implications (e.g., diversification rates, paleobiogeography) for our confidence in the fossil record of arvicolines and their utility as biochronological tools in Eurasia and North America during the Quaternary.
Ecological condition of coastal ocean waters within Stellwagen Bank National Marine Sanctuary, 2008

In June 2008, the NOAA National Ocean Service (NOS), in conjunction with the EPA National Health and Environmental Effects Laboratory (NHEERL), conducted an assessment of the status of ecological condition of soft-bottom habitat and overlying waters within the boundaries of Stellwagen Bank National Marine Sanctuary (SBNMS). The sanctuary lies approximately 20 nautical miles east of Boston, MA in the southwest Gulf of Maine between Cape Ann and Cape Cod and encompassing 638 square nautical miles (2,181 km2). A total of 30 stations were targeted for sampling using standard methods and indicators applied in prior NOAA coastal studies and EPA’s Environmental Monitoring and Assessment Program (EMAP) and National Coastal Assessment (NCA). A key feature adopted from these studies was the incorporation of a random probabilistic sampling design. Such a design provides a basis for making unbiased statistical estimates of the spatial extent of ecological condition relative to various measured indicators and corresponding thresholds of concern. Indicators included multiple measures of water quality, sediment quality, and biological condition (benthic fauna, fish tissue contaminant levels). Depths ranged from 31 – 137 m throughout the study area. About 76 % of the area had sediments composed of sands ( 80 % siltclay). About 70 % of the area (represented by 21 sites) had sediment total organic carbon (TOC) concentrations 50 mg/g). Surface salinities ranged from 30.6 – 31.5 psu, with the majority of the study region (approximately 80 % of the area) having surface salinities between 30.8 and 31.4 psu. Bottom salinities varied between 32.1 and 32.5 psu, with bottom salinities at all sites having values above the range of surface salinities. Surface-water temperatures varied between 12.1 and 16.8 oC, while near-bottom waters ranged in temperature from 4.4 – 6.2 oC. An index of density stratification (Δσt) indicated that the waters of SBNMS were stratified at the time of sampling. Values of Δσt at 29 of the 30 sites sampled in this study (96.7 % of the study area) varied from 2.1 – 3.2, which is within the range considered to be indicative of strong vertical stratification (Δσt > 2) and typical of the western Gulf of Maine in summer. Levels of dissolved oxygen (DO) were confined to a fairly narrow range in surface (8.8 – 10.4 mg/L) and bottom (8.5 – 9.6 mg/L) waters throughout the survey area. These levels are within the range considered indicative of good water quality (> 5 mg/L) with respect to DO. None of these waters had DO at low levels (< 2 mg/L) potentially harmful to benthic fauna and fish.
Multiparametric Correlation Between Anatomical Variants of the Paranasal Sinuses and Chronic Rhinosinusitis: Case-control Study

Introduction: Chronic rhinosinusitis (RSC) is a disabling disease that can affect up to 70% of people. It is very important to know which are the anatomical variants that the patient presents for surgical planning and often for the treatment of the variants that can present as a risk factor. The evidence shows heterogeneity in the prevalence of these anatomical variants and it is not described quantitatively which are the variants that present the greatest relationship as a risk factor. Establishing the multiparametric correlation between at least one of the most frequent anatomical variants of the paranasal sinuses and the development of rhinosinusitis is the most important objective of this investigation. Materials and methods: Case-control study with multiparametric correlation analysis of the anatomical variants of paranasal sinuses as a risk factor in the development of sinusitis. Analysis with measures of central tendency, Xi2, Fisher's exact test, binary logistic regression. Results: The most frequent anatomical variant was the deviation of the nasal septum on the left side (78%). The second most common variant found was the Agger Nasi cells (68%), followed by the protrusion of the Vidian nerve in the sphenoid sinus (52%). The only anatomical variant that could be determined within the regression model was the obstruction of the osteomeatal complex; which is presented as a risk factor with an OR of 16 (95% CI: 6.9-41.3). Conclusions: Obstruction of the osteomeatal complex is a very important risk factor for the development of chronic rhinosinusitis.
Caractéristiques pétrologiques des dolérites tholéiitiques d'âge triasique (ophites) du domaine pyrénéen

De nouvelles donnees sur les dolerites tholeiitiques des Pyrenees ("ophites") ont pu etre obtenues a partir de l'etude des quelques gisements ou ces roches ne sont pas metamorphisees, en particulier au Nord de l'Espagne. Le caractere hypovolcanique de ces tholeiites a quartz normatif permet d'observer, dans les gisements les plus importants, des phenomenes de fractionnement depuis des facies cumules a orthopyroxene (MgO~15 %) jusqu'a des pegmatitoides (MgO~5 %). ; Une etude a la microsonde montre l'importante zonation des principales phases : olivine, plagioclase et surtout pyroxenes (augite, pigeonite et orthopyroxene), et permet de suivre l'evolution des liquides dans chaque facies. Dans les phases tardives, comportant du quartz et des micropegmatites, plusieurs mineraux ont ete mis en evidence : des silicates de Zr et de TR (zircon, allanite et parfois chevkinite-perrierite), ainsi que des amphiboles (ferroedenites) et des biotites riches en fer et surtout en chlore. Au cours du refroidissement et en liaison avec des microfractures, les pyroxenes magmatiques riches en fer peuvent etre remplaces par des salites pauvres en Al et Ti associees a des oxydes de fer. ; Ces dolerites sont une expression de l'important magmatisme tholeiitique continental periatlantique d'âge triasico-jurassique.
Harnessing the Science of Social Marketing and Behaviour Change for Improved Water Quality in the GBR: background review of the literature

This document is intended to provide an extensive review of the existing literature relating to behaviour change, either directly in the agri-environment context, or from wider contexts where findings may then be applied to agri-environmental issues. A specific focus is placed on the use of social marketing approaches, acknowledging the complex range of influences on behaviours and pressures, such as climate change and extreme weather events that are beyond the control of land managers.