Miracle-dz/UniFAR-FTUs huggingface dataset:
Our Experiences with Asparaginase Activity Measurements in Children with Lymphoblastic Diseases

Background: Asparaginase is a key component of chemotherapy protocols for the treatment of lymphoblastic malignancies among children. Adequate asparagine depletion is an important factor to achieve optimal therapeutic outcomes. Methods: Over a 3.5 year period, 106 patients were monitored for asparaginase activity (329 samples) in a single center of the Hungarian Pediatric Oncology–Hematology Group. In Hungary, three asparaginase products are available: native E. coli ASNase (Kidrolase), a pegylated form of this enzyme (Pegaspargase) and another native product from Erwinia chrysanthemi (Erwinase). A retrospective data analysis was performed. Results: In 81% (268/329) of our patients, AEA levels were in the optimal therapeutic range of over 100 IU/L. Of 106 patients, 13 (12%) were diagnosed with ‘silent inactivation’. Conclusions: Monitoring of AEA can help to identify patients with ‘silent inactivation’ and their asparaginase therapy can thus be optimized.
Application of epidural steroid injection for the treatment of lumbar disc herniation in Vietnam

Epidural steroid injections (ESIs) have been mentioned by international medical literature as an option for treatment and pain relief for patients with lumbar disc herniation (LDH). Several studies worldwide have recognized the efficacy of treating LDH with ESIs to be between 72-86%. Our study aimed to elucidate the ESIs technique's effectiveness, advantages, and disadvantages. A 30-day pre-post study in 100 LDH patients underwent the ESIs technique. Patients meeting the criteria received physical examinations and magnetic resonance imaging (MRI) scans before undergoing the method. The Visual Analog Scale (VAS) was applied to assess the patient's hospitalization condition after ESIs 1 day, 7 days, and 30 days. After 1 day of ESIs, 85% of patients responded well (10% excellent and 75% moderate), and this prevalence increased up to 95% after 7 days and 30 of follow-up. The ESIs safety assessment after 1 day of treatment recorded that 2% of patients had complications and 24% had medication side effects. After 7 days, 4% of patients had epigastric pain and no more complications. Treatment outcomes of ESIs were effective and high safety in patients with LDH.
THE EFFECTIVENESS OF REALISTIC MATHEMATICS EDUCATION LEARNING APPROACH ON CRITICAL THINKING SKILLS OF ELEMENTARY SCHOOL STUDENTS

Critical thinking is an ability that students must have to make a reasonable decision based on facts in solving a problem correctly. But in reality not all students have this ability. This study aims to determine the effectiveness of applying the Realistic Mathematics Education approach compared to the direct learning model on the critical thinking skills of elementary school students. This study uses a quasi-experimental method. The research design was a non-equivalent control group design. The sample of this research is the fourth grade students of SDN 2 Mangunrejo as the experimental class and the fourth grade students of SDN 3 Mangunrejo as the control class. The instrument used to measure critical thinking skills is a written test. The average value of student learning outcomes for the experimental class is 82.30, while the control class is 62.33. Thus it can be concluded that there is a difference in the average student learning outcomes between the RME class and the control class. The results of the Independent Sample t-test showed a sig (2-tailed) value of 0.00 0.05 so it can be concluded that there is a significant difference between the average student learning outcomes in the RME class and the control class. From the results of data analysis, it can be concluded that the Realistic Mathematics Education approach is more effective in improving critical thinking skills when compared to the direct learning model.
Type 2 diabetes and in-hospital sudden cardiac arrest in ST-elevation myocardial infarction in the US

Aims We aimed to assess the impact of diabetes on sudden cardiac arrest (SCA) in US patients hospitalized for ST-elevation myocardial infarction (STEMI). Methods We used the National Inpatient Sample (2005–2017) data to identify adult patients with STEMI. The primary outcome was in-hospital SCA. Secondary outcomes included in-hospital mortality, ventricular tachycardia (VT), ventricular fibrillation (VF), cardiogenic shock (CS), acute renal failure (ARF), and the revascularization strategy in SCA patients. Results SCA significantly increased from 4% in 2005 to 7.6% in 2018 in diabetes patients and from 3% in 2005 to 4.6% in 2018 in non-diabetes ones (p < 0.001 for both). Further, diabetes was associated with an increased risk of SCA [aOR = 1.432 (1.336–1.707)]. In SCA patients with diabetes, the mean age (SD) decreased from 68 (13) to 66 (11) years old, and mortality decreased from 65.7% to 49.3% during the observation period (p < 0.001). Compared to non-diabetes patients, those with T2DM had a higher adjusted risk of mortality, ARF, and CS [aOR = 1.72 (1.62–1.83), 1.52 (1.43–1.63), 1.25 (1.17–1.33); respectively] but not VF or VT. Those patients were more likely to undergo revascularization with CABG [aOR = 1.197 (1.065–1.345)] but less likely to undergo PCI [aOR = 0.708 (0.664–0.754)]. Conclusion Diabetes is associated with an increased risk of sudden cardiac arrest in ST-elevation myocardial infarction. It is also associated with a higher mortality risk in SCA patients. However, the recent temporal mortality trend in SCA patients shows a steady decline, irrespective of diabetes.
Frequency Diversity Using Random Time Delay in Amplify-And-Forward Relay

In a tactical wireless communication environment, it is common for device-to-device communication to occur without a base station, but this can be problematic when the distance between the source and destination is too far. Relays are often used to improve transmission distance and reliability, but amplification-based relaying can result in lower communication performance compared to other methods. This paper proposes a method for obtaining diversity gain through the application of time delay during relaying. The proposed method is compared to a conventional method that uses phase rotation to obtain diversity gain. Simulation results show that the proposed method has slightly lower or similar performance improvement compared to the conventional relay method.
Effects of emotional regulation and impulsivity on sports performance: the mediating role of gender and competition level

Introduction This study aimed to study the relationships between emotional regulation and impulsivity on sports performance, according to the gender and competition level in national-level volleyball players. Methods In total, 77 players from the 2018–2019 top two Spanish divisions completed the ERQ (emotion regulation) and the UPPS-P (impulsivity). Statistics (serve, reception, and attack) were retrieved from the Spanish Volleyball Federation. A Mann–Whitney test was conducted to determine differences between gender and competition level in impulsivity and emotion regulation. A Kruskal–Wallis test (Mann–Whitney post-hoc) was carried out for playing positions analysis. Spearman's correlation was performed between the performance and the variables of impulsivity and emotional regulation. Results The results obtained, with differences according to playing position, gender, and competition level, show that players differ in certain psychological aspects that might influence how they approach their game. Discussion The results point in a promising direction: the sports practice analyzed can serve as a regulation context, for both the emotional response and the level of impulsivity of the players. The importance of these results for future research on this topic is discussed.
Sports Education as a Means of Building Student Character: Values and Benefits

Sports education offers a unique opportunity for character-building in students. The benefits of sports education go beyond just physical health. It has been found to play an important role in building character and teaching values essential for success in life. Grounded on this belief, this study examines the values that sports education can teach and their potential benefits. A qualitative research approach was employed using interviews and observations of students participating in sports education programs. The data obtained from the field were analyzed thematically. From the analysis, it is indicated that sports education can teach important values such as teamwork, leadership, determination, and sportsmanship. Additionally, sports education can benefit students, such as improved physical fitness, self-confidence, and social skills. Overall, this study suggests that sports education can play a significant role in character development and has the potential to impact students both on and off the field positively.
Case Studies of Extreme Wave Analysis: A Comparative Analysis

Several methods of extremal wave analysis have been applied to two sets of deep water extreme wave data. One set consisted of three-hourly sea-state records collected during a nine year period with a wave buoy at Haltenbanken off the Norwegian coast. The other set comprised a 20-year period of storm peak wave heights, obtained via a numerical hindcast of historical storms. For both data sets, 100-year return wave heights with corresponding 90% confidence intervals were computed with a variety of extremal analysis techniques, including the Initial Distribution Method, the Annual Maxima Method, and the Peak over Threshold Method. FT-I, Weibull and other probability distributions were fitted to the data by the Method of Moments, Least Squares Method, and the Maximum Likelihood Method. The results of the study show that for both data sets the estimated 100-years return wave heights differ less than 10% of one another. It was also found that the effect of choices in the data selection, e.g., the choice of the threshold, has a significant effect on the estimated wave heights.
An exploration into the impact of citizen journalism on traditional journalism in Lesotho

In recent years, technological advancement in communication has given citizens opportunities to be recipients and purveyors of news. Social networking sites propagate citizen journalism, wherein ordinary citizens without professional training gather and disseminate information. This has presented a number of challenges due to limited quality control standards for determining what constitutes news. The study thus sought to establish the depth and breadth of the impact of citizen journalism on traditional journalism in Lesotho. The study used the qualitative methodology embedded in a case study design. The in-depth face-to-face interviews with (n=10) journalists were conducted to get insight into the impact citizen journalism has on traditional media. The respondents were selected using a purposive sampling technique. In this case, respondents were selected based on their availability and knowledge of the subject at hand. The findings were analysed using thematic analysis to interpret the findings. The results revealed that citizen journalism had posed an imminent threat to traditional journalism as it plays a complementary role. It was also discovered that the fast passed nature of citizen journalists compromises the quality of the content. The study also revealed that mainstream media professionals face fierce competition from citizen journalism, resulting in poor-quality stories. Therefore, the study recommends that mainstream media should have platforms where citizen journalists can submit content that can be vetted for quality control and ethical considerations.
Comparison of RANS and Detached Eddy Simulation Modeling Against Measurements of Leading Edge Film Cooling on a First-Stage Vane

The performance of a showerhead arrangement of film cooling in the leading edge region of a first-stage nozzle guide vane was experimentally and numerically evaluated. A sixvane linear cascade was tested at an isentropic exit Mach number of Ma2s = 0.42, with a high inlet turbulence intensity level of 9%. The showerhead cooling scheme consists of four staggered rows of cylindrical holes evenly distributed around the stagnation line, angled at 45 deg toward the tip. The blowing ratios tested are BR = 2.0, 3.0, and 4.0. Adiabatic film cooling effectiveness distributions on the vane surface around the leading edge region were measured by means of thermochromic liquid crystals (TLC) technique. Since the experimental contours of adiabatic effectiveness showed that there is no periodicity across the span, the computational fluid dynamics (CFD) calculations were conducted by simulating the whole vane. Within the Reynolds-averaged Navier-Stokes (RANS) framework, the very widely used realizable k-e (Rke) and the shear stress transport k-ω (SST) turbulence models were chosen for simulating the effect of the BR on the surface distribution of adiabatic effectiveness. The turbulence model which provided the most accurate steady prediction, i.e., Rke, was selected for running detached eddy simulation (DES) at the intermediate value of BR = 3. Fluctuations of the local temperature were computed by DES, due to the vortex structures within the shear layers between the main flow and the coolant jets. Moreover, mixing was enhanced both in the wall-normal and spanwise directions, compared to RANS modeling. DES roughly halved the prediction error of laterally averaged film cooling effectiveness on the suction side of the leading edge. However, neither DES nor RANS provided the expected decay of effectiveness progressing downstream along the pressure side, with 15% overestimation of ηav at s/C = 0.2.
Determining Factors of Asset Misappropriation Tendency by Employees in Perspective of Fraud Hexagon Theory

AbstractPurpose: This study aims to provide empirical evidence and analyze factors that contribute to asset misappropriation by employees through the fraud hexagon theory perspective. The theory consists of six components that trigger fraud, such as stimulus (incentives), opportunities, rationalization, capabilities, ego, and collusion. In this study, the stimulus factor is divided into financial and non-financial (job pressure). Method: The study obtains data by distributing questionnaires to 218 participants employees from 5 departments of XTZ Hospital in Semarang. Only those who work in structural and functional positions are the participants, considering they are responsible for the hospital asset management. To collect data, this study implements a proportional stratified random sampling method, and test the hypothesis by using the 7.0 version of WarpPLS analysis tool.Findings: The results indicate that financial pressure, opportunity, capability, ego, and collusion influence asset misappropriation. Meanwhile, non-financial pressure (job pressure) and rationalization do not contribute to misappropriation.Novelty: This research implies an overview of why the management has to carefully review the factors that lead to asset misappropriation in the workplace. Besides, these can be used for formulating guidelines to prevent misappropriation. Keywords: Financial pressure, fraud hexagon theory, asset misappropriation
Titan's interaction with the Saturnian magnetosphere

In this thesis, a combination of data analysis and test particle simulations is used in order to study several aspects of the complex interaction of Titan with the Saturnian magnetosphere. First, the energetic charged particles environment at the orbital distance of Titan is studied using data from the MIMI/LEMMS instrument. Average fluxes and spectral slopes for energetic ions and electrons are analysed. A large variability is found, and it is interpreted as originated from the high mobility of the energetic ions and electrons, making a simple classification of this environment practically impossible, with only a weak correlation between the ion average fluxes with the plasma environment detectable and an asymmetry between the noon-to-dusk and midnight-to-dawn sectors. Second, the effect of local electromagnetic field disturbances in the access of energetic H+ and O+ ions is studied. By studying the trajectories of individual particles to predict where they will deposit their energy, differences in ionisation rates at different locations around the moon of almost 80% are found for H+ ions and of more than 15% for the case of O+ ions. Finally, the contribution of freshly produced pickup ions to the overall mass loss of the atmosphere is investigated by looking at particular signatures left by these ions in the thermal plasma data from the CAPS/IMS instrument. A statistical survey of all the flybys with available data leads to a constraint of the region around the moon where these ions are detected. Mass losses on the anti-Saturn side of the moon of between 570 kg/day and 1 tonne/day are derived depending on the species, accounting for a small fraction of the total losses estimated from distant tail observations.
Increasing the Learning Interest of Fourth Grade Elementary School Students with Mission Book Game

Minimnya media pembelajaran yang dapat meningkatkan minat belajar siswa membuat proses pembelajaran yang bermakna kurang optimal. Penelitian ini bertujuan untuk mengembangkan media mission book game yang dinyatakan layak digunakan dalam pembelajaran dan efektif dalam meningkatkan minat belajar siswa kelas IV. Penelitian pengembangan ini menggunakan metode pengembangan ADDIE. Subjek penelitian dalam penelitian pengembangan media pembelajaran ini adalah 2 orang ahli materi, 2 orang ahli media, 2 orang praktisi, dan 15 orang siswa. Metode pengumpulan data dalam penelitian ini adalah angket untuk memperoleh data dari pakar, praktisi dan tanggapan siswa tentang akseptabilitas media pembelajaran mission book game. Kuesioner digunakan untuk mengukur minat siswa dalam menggunakan mission book game ini. Hasil penelitian menunjukkan bahwa media mission book game telah dinyatakan valid, praktis, dan efektif untuk meningkatkan minat belajar siswa. Hal ini terlihat dari hasil analisis uji validitas media dengan ahli isi, rata-rata skor keseluruhan sebesar 4,2 dengan kriteria sangat valid, ahli media secara keseluruhan sebesar 4,6 dengan kriteria sangat valid, respon praktisi secara keseluruhan sebesar 4,6 dengan kriteria sangat valid, dan tanggapan siswa (tes individu dan tes kelompok kecil) secara keseluruhan adalah 4,4 dan 4,2 dengan kriteria sangat valid. Berdasarkan hasil uji keefektifan, siswa yang belajar dengan bantuan permainan buku misi memiliki minat belajar yang lebih tinggi dibandingkan siswa yang belajar tanpa bantuan media mission book game.
Does import quality affect Brazilian wages?

In this paper, we investigated whether import quality affects wages paid by sectors facing import competition in Brazil from 1997 to 2016. First, we estimated a fixed effects model and, then, an unconditional quantile regression. We found that the quality of imports positively impacts Brazilian wages and that import quality affects wage bands differently in Brazil. In addition, we determined that the quality of imports originated in poorer economies has a slightly greater effect on wages in respect of richer countries. We concluded that, to fight international competition, local firms might improve product quality by hiring skilled workers, who earn more, and that the raise in the wage bill varies depending on the exporter income
The Association between ideology and resistance to governmental apology depends on political knowledge

Abstract This study examines the relationship between ideology and resistance to the government's apology to Asian victims of Japan's colonial rule policy, which varies according to political knowledge. Based on existing research, because only a limited percentage of voters consider politics to be ideology based, it is expected that the association between ideology and resistance to intergroup apologies by one's own government differs according to their level of political knowledge. We selected three issues of political apologies: colonial rule in Asian countries, comfort women, and the massacre of Korean people based on false rumors at the time of the 1923 Kanto Earthquake; thereafter, we conducted an online survey of a panel selected by Nikkei Research Inc. The results suggest that the relationship between ideology and resistance among voters to political apologies varies with the level of political knowledge, as expected. On the contrary, social dominance orientations (SDO) were associated with resistance to apology, regardless of their level of political knowledge. We then tested the reproducibility of this finding by conducting a follow-up test on registered users of a crowdsourcing service after conducting a preregistration. In addition, we also measured general attitudes toward personal apologies and neighboring countries victimized by Japan's colonialist policies as factors that might predict resistance to apologies even among the politically uninformed. The association between ideology, SDO, and resistance to governmental apologies was generally replicated in this study.
Model identification of reduced order fluid dynamics systems using deep learning

This paper presents a novel model reduction method: deep learning reduced order model, which is based on proper orthogonal decomposition and deep learning methods. The deep learning approach is a recent technological advancement in the field of artificial neural networks. It has the advantage of learning the nonlinear system with multiple levels of representation and predicting data. In this work, the training data are obtained from high fidelity model solutions at selected time levels. The long short‐term memory network is used to construct a set of hypersurfaces representing the reduced fluid dynamic system. The model reduction method developed here is independent of the source code of the full physical system.
Factors Associated with Major Complications at 90-Days after Liver Transplantation

Purpose: Postoperative complications are associated with graft recipient loss or death in Liver Transplantation (LT). We aimed to explore perioperative factors associated with complications at 90 days after LT. Methods: Secondary analysis of data for 176 patients from a multicenter randomized trial. Main exclusion criteria was patients at low risk for intraoperative transfusion (preoperative Hemoglobin [Hb] concentration >130 g/L). The primary outcome was the incidence of complications defined by a Clavien-Dindo classification of 3 to 5 (CDC 3-5) at 90 days after LT. The secondary outcome was acute
Understanding the Nature of Psychokinesis

This paper is the extended transcript of a lecture of November 2, 2021, presented online at the Colloquia of the Institut für Grenzgebiete der Psychologie und Psychohygiene (IGPP). 2 It concerns a novel type of analysis of the micro-psychokinesis (MicroPK) meta-analysis data, BSB-MA, of carefully selected studies (Bösch et al., 2006a). The current paper introduced scientifically recognized data analyses other than the usual statistical approaches that yielded controversially debated conclusions. The method of Rescaled Range Analysis and the Markov model revealed correlations in the BSB-MA database introduced by three biases acknowledged in experimental science that altered some of the data: The Experimenter Expectancy Effect, the Conformity, and the Publication biases. They shaped the scatter of the random BSB-MA scores on the funnel plot. Most errors the biases have introduced were unintentional. Two interpretations of the evidence in the BSB-MA database based on the scientific method are likely: the paranormal, which explains some of the evidence, and the non-paranormal, which accounts for all evidence the present analyses realized. The principle of parsimony favors the latter interpretation.