Miracle-dz/UniFAR-FTUs huggingface dataset:
In Vivo Zymosan Treatment Induces IL15-Secreting Macrophages and KLRG1-Expressing NK Cells in Mice

Beta-glucan (β-glucan) is a natural polysaccharide produced by fungi, bacteria, and plants. Although it has been reported that β-glucan enhances innate immune memory responses, it is unclear whether different types of β-glucans display similar immune effects. To address this issue, we employed zymosan (β-1,3-glycosidic linkage) and pustulan (β-1,6-glycosidic linkage) to investigate their in vivo effects on innate memory immune responses. We examined the changes of innate memory-related markers in macrophages and natural killer (NK) cells, two immune cell types that display innate memory characteristics, at two different time points (16 h and 7 days) after β-glucan stimulation. We found that short-term (16 h) zymosan treatment significantly induced macrophages to upregulate IL15 production and increased surface IL15Rα expression on NK cells. In addition, long-term (7 days) zymosan treatment significantly induced macrophages to upregulate the expression of innate memory-related markers (e.g., TNFα, HIF1α, and mTOR) and induced NK cells to express enhanced levels of KLRG1, known as an innate memory-like marker. Our results provide support that zymosan can be an effective adjuvant to promote innate memory immune responses, providing a bridge between innate and adaptive immune cells to enhance various immune responses such as those directed against tumors.
Unraveling Induction Motor State through Thermal Imaging and Edge Processing: A Step towards Explainable Fault Diagnosis

Equipment condition monitoring is essential to maintain the reliability of the electromechanical systems. Recently topics related to fault diagnosis have attracted significant interest, rapidly evolving this research area. This study presents a non-invasive method for online state classification of a squirrel-cage induction motor. The solution utilizes thermal imaging for non-contact analysis of thermal changes in machinery. Moreover, used convolutional neural networks (CNNs) streamline extracting relevant features from data and malfunction distinction without defining strict rules. A wide range of neural networks was evaluated to explore the possibilities of the proposed approach and their outputs were verified using model interpretability methods. Besides, the top-performing architectures were optimized and deployed on resource-constrained hardware to examine the system's performance in operating conditions. Overall, the completed tests have confirmed that the proposed approach is feasible, provides accurate results, and successfully operates even when deployed on edge devices.
Effectiveness of Multimedia Courseware Based Instruction on Senior School Students’ Retention in Linear Equation Word Problems

The increasing popularity of Multimedia courseware in education aims to address the challenges posed by abstract concepts and the consequent underachievement of students. It is also relevant to consider the limitations of working memory resources during multimedia courseware based instruction of abstract concepts in order to evaluate irrelevant factors that create unwanted cognitive drain and make retention difficult. The study investigated the effects of multimedia courseware based instruction on senior school students’ achievement and retention in linear equation word problems in Mathematics. The study adopted a quasi-experimental research design. In Gombe State Nigeria, 120 students (69 males and 51 females) were selected from three co-educational senior schools allocated either into experimental group or a control group. The results of the study indicated that students exposed to multimedia courseware based instruction achieved and retained linear equation word problems than their counterparts who were exposed to conventional teaching method. There was significant difference between the mean retention scores of male and female students exposed to multimedia courseware based instructions which the result is in favor of female students. High, medium and low achievers’ students exposed to multimedia courseware based instructions retained the concept of linear equations involving word problems and high scorer retained better. Based on the above findings it was recommended that multimedia courseware based instruction should be used in teaching and learning of Mathematics as it was found capable of improving students’ retention in linear equation word problems in Mathematics.
Impact of Brand Capital on the Stock Price Crash Risk, an Empirical Study

The factors influencing the financial market are rapidly becoming more complex. The impact of non-financial factors on the performance of a company’s common stock can increase in ways that were not previously expected. This study investigated how brand capital affects the risk of stock prices in Iraqi private banks listed on the Iraq Stock Exchange failing by identifying the likelihood of a crash caused by a negative deviation in the distribution of returns on ordinary shares. As a result, the current study’s concept is to review an analytical knowledge framework of the nature of that relationship, its changes, and its impact on the pricing of ordinary shares of the banks of the researched sector for the years 2009 to 2017, as well as by the 21 banks listed during that time and by the 588 observations using the expanded market model to determine quarterly changes in stock prices. In addition to testing the negative coefficient of skewness and the down-to-up volatility models to test the contribution of brand capital in reducing the risk of stock collapse, The test results showed that brand capital is closely related to the significant and adverse risks of a stock crash. Additionally, the first’s impact is inverse, as its content highlights the role that the research sample banks’ brand capital played in lowering the dangers of stock price crashes.
The effects of forced small-wavelength, finite-bandwidth initial perturbations and miscibility on the turbulent Rayleigh–Taylor instability

Rayleigh–Taylor instability experiments are performed using both immiscible and miscible incompressible liquid combinations having a relatively large Atwood number of $A\equiv ({\it\rho}_{2}-{\it\rho}_{1})/({\it\rho}_{2}+{\it\rho}_{1})=0.48$ . The liquid-filled tank is attached to a test sled that is accelerated downwards along a vertical rail system using a system of weights and pulleys producing approximately $1g$ net acceleration. The tank is backlit and images are digitally recorded using a high-speed video camera. The experiments are either initiated with forced initial perturbations or are left unforced. The forced experiments have an initial perturbation imposed by vertically oscillating the liquid-filled tank to produce Faraday waves at the interface. The unforced experiments rely on random interfacial fluctuations, resulting from background noise, to seed the instability. The main focus of this study is to determine the effects of forced initial perturbations and the effects of miscibility on the growth parameter, ${\it\alpha}$ . Measurements of the mixing-layer width, $h$ , are acquired, from which ${\it\alpha}$ is determined. It is found that initial perturbations of the form used in this study do not affect measured ${\it\alpha}$ values. However, miscibility is observed to strongly affect ${\it\alpha}$ , resulting in a factor of two reduction in its value, a finding not previously observed in past experiments. In addition, all measured ${\it\alpha}$ values are found to be smaller than those obtained in previous experimental studies.
Displacement Effects in Manufacturing and Structural Change

IZA DP No. 16344 JULY 2023 Displacement Effects in Manufacturing and Structural Change* We investigate the consequences of structural change for workers displaced from the manufacturing sector. Manufacturing establishments traditionally employed lowand high-wage workers in similar proportions and paid substantial wage premiums to both types of workers. Structural change has led to the disappearance of these jobs, particularly for low-wage workers. Decomposing displacement wage losses, we show that low-wage workers suffer considerable losses in establishment premiums following displacement, whereas high-wage workers tend to fall down the match quality ladder. With ongoing structural change, losses in wages and establishment premiums have increased over time, especially for low-wage workers, in part because they are increasingly forced to switch to low-knowledge service jobs where establishment premiums are low. Our findings further highlight that structural change and layoffs in manufacturing have significantly contributed to job polarization and the rise in assortative matching of workers to firms. JEL Classification: J22, J24, J31, J63
EFFECTS OF ROTATION ON TURBULENT CHANNEL FLOWS

A novel setup for flow visualizations and turbulence measurements in rotating high-aspectratio ducts is presented. Results from 3-component SPIV measurements show the significant effect of system rotation both on the mean flow and on the turbulence statistics in a clear channel. Combined 2-component PIV measurements allow detailed studies on massively separated flows subjected to rotation in both directions.
The Influence of Entrepreneurship Education, Entrepreneurial Knowledge and Entrepreneurial Inspiration on Generation Z’s Entrepreneurial Intention

This study aims to examine the effect of entrepreneurship education on students' entrepreneurial intentions, as well as examine the mediating role of entrepreneurial knowledge and entrepreneurial inspiration. This study uses primary data obtained from a sample of 192 students at SMAN 108 Jakarta. In addition, the analytical method used in this study is SEM-PLS analysis method. The findings of this study strengthen the study of the influence of entrepreneurship education both directly and indirectly through entrepreneurial knowledge and entrepreneurial inspiration on entrepreneurial intentions. In addition, it found direct and indirect effects of entrepreneurship education on entrepreneurial intentions through entrepreneurial knowledge and entrepreneurial inspiration. This research was limited to one school and with limited variables, there are entrepreneurship education, entrepreneurial knowledge, entrepreneurial inspiration and entrepreneurial intention. The findings of this study provide insight into increasing entrepreneurial intentions by increasing the effectiveness of learning entrepreneurship education in schools.
Weight Is a Predictor of Delayed Operation Time in Primary Isolated Anterior Cruciate Ligament Reconstruction

Background: Few studies have evaluated the impact of obesity on operation time in patients with ACL reconstruction. The purpose of this study was to understand the effect of obesity on operation time in patients with arthroscopic anterior cruciate ligament (ACL) reconstruction. Methods: A total of 103 patients were included. The mean pure operation time was 45.9 ± 13.4 min. Considering that 15 min incremental increases in operation time are an independent risk factor for complications, all patients were classified into two groups according to operation time: more or less than 61 min. Demographic data were compared between both groups. Pure operation time was defined as operative time without suture time (pure operation time = suture start time − operation start time). Correlation analysis between demographic data and pure operation time was performed, and multiple linear regression analysis was used to identify the predictors of pure operation time. Results: The pure operation time ≥61 min group (n = 34) had a 14.7 kg higher weight and 4.5 kg/m2 higher body mass index (BMI) than those with pure operation time < 61 min (n = 69). Weight (r = 0.635, p < 0.001) and BMI (r = 0.584, p < 0.001) were positively correlated with operation time. Multiple linear regression analysis showed that weight (β = 0.635, p < 0.001) was the only predictor of operation time. A weight of 74.25 kg was a cut-off value for a pure operation time of >61 min. Conclusions: The weight and BMI of the group with pure operation time of ≥61 min were 14.7 kg and 4.5 kg/m2 higher, respectively. The weight of patients with ACL tears was a factor affecting delay in the operation time. Patients weighing over 74.25 kg were more likely to delay ACL reconstruction.
The Influence Of Service Quality Dimensions On Customer Loyalty With Customer Satisfaction As An Intervening Variable

This study aims to determine the effect of the dimensions of service quality on customer loyalty at the coffee shop, with customer satisfaction as the intervening variable. The research method used in this study is a quantitative method by giving questions to a number of respondents using a questionnaire on the form (google form). The results of this study show that the responsiveness and empathy variables have a direct and significant influence on customer satisfaction at the Laju Coffee shop and this study also proves that the customer loyalty at Laju Coffee Shop is also influenced by the customer satisfaction.
Vitamin E Ameliorates Impaired Ovarian Development, Oxidative Stress, and Disrupted Lipid Metabolism in Oreochromis niloticus Fed with a Diet Containing Olive Oil Instead of Fish Oil

Aquaculture feed containing olive oil (OO) instead of fish oil (FO) can cause oxidative stress and impair gonad development in fish. We determined the effect of dietary OO-induced oxidative stress on ovarian development, and explored whether vitamin E (VE) could mitigate negative effects. Female Nile tilapia (Oreochromis niloticus) were fed for 10 weeks with four diets: 5% OO + 70 mg/kg VE, 5% OO + 200 mg/kg VE, 5% FO + 70 mg/kg VE, or 5% FO + 200 mg/kg VE. Dietary OO reduced the specific growth rate and gonadosomatic index, inhibited superoxide dismutase and catalase, delayed ovarian development, decreased serum sex hormone levels, and reduced ovarian triglyceride and n-3 highly unsaturated fatty acid contents. The transcript levels of genes encoding sex hormone receptors (erα, fshr, lhr) and components of the lipid metabolism pathway (pparα, pparγ, hsl, accα, elovl6), the nrf2 signaling pathway (nrf2, keap1), and the nf-κb signaling pathway (nf-κb, tnfα, infγ, il1β) differed between the 70VE/OO and 70VE/FO groups. Supplementation with 200 mg/kg VE mitigated the adverse effects of OO by improving antioxidant capacity and alleviating inflammation and abnormal lipid metabolism. This may be because VE is an antioxidant and it can regulate the nrf2-nf-κb signaling pathway.
Direct numerical simulation of controlled turbulent duct flows

Direkte numerische Simulationen von kontrollierten turbulenten Stromungen werden im Kanal unter Berucksichtigung der Seitenwande mit dem spectral element code Nek5000 Fischer et al. (2008) durchgefuhrt. Die verwendete Technik zur Stromungskontrolle ist die harmonische Oszillation der horizontalen Wande zum Zwecke der Reduktion der turbulenten Reibung. Nach bestem Wissen des Autors ist dies das erste Mal in der diese Technik zur Stromungskontrolle in in einem Kanal mit Seitenwanden numerisch untersucht wird. Verschiedene Parameter der Stromungskontrolle, und zwar die Wandgeschwindigkeitsamplitude und die kontrollierte Flache, werden in drei unterschiedlichen Fallen getestet und ihre Ergebnisse untereinander und mit dem unkontrollierten Fall verglichen. Zwei Effekte dieser Technik zur Stromungskontrolle im rechteckigen Kanal mit Seitenwanden werden untersucht: der Effekt auf die Reibungsminderung und der Effekt auf die Sekundarstromungen, welche durch die Ecken im Kanal erzeugt werden. Zusatzlich werden einige gemittelte Statistiken ausgewertet um die Auswirkung der bewegten Wande auf die turbulente Stromung zu verstehen. Die Sekundarstromung wird verglichen zum unkontrollierten Fall stark angefacht und in Gestalt und Lage verandert. Einer der entgegengesetzt rotierenden Wirbeln in der Ecke wird verstarkt und verdrangt den anderen Wirbel naher ins Zentrum des Kanals. Im Falle von nur teilweise kontrollierten horizontalen Wanden wird ein weiteres Paar von entgegengesetzt rotierenden Wirbeln erzeugt. Das erzielte Niveau der Reibungsminderung ist verglichen zu den Ergebnissen im Kanal ohne Seitenwande sehr gering. Die einzige positive Reibungsminderung, die erreicht wird betragt 3% in einem Fall bei dem 19% im Kanal ohne Seitenwande erreicht wird. Der Fall mit hoherer Wandgeschwindigkeitsamplitude ergibt eine Reibungserhohung von 10% und im Falle verkleinerter Flache der Stromungskontrolle nur im Zentrum des Kanals ergibt sich eine Reibungserhohung von 1%. Es wird gezeigt, dass diese niedrigen oder sogar negativen Werte der Reibungsminderung ein Resultat der schlechten Performance an den Seiten des kontrollierten Gebiets sind.
Selective radial release of hot, magnetised electrons downstream of a low-pressure expanding plasma

A thorough understanding of particle transport in expanding plasma devices under different geometric and magnetic configurations is necessary for future thruster and reactor design. Recently, we have shown that the development of high density conics via hot electron transport along the most radial field lines escaping the source region of an expanding plasma device is crucial for the development of a high velocity ion beam on axis. In this study, a gap between the source region and a movable extension tube inserted in the downstream of an expanding plasma device is used to create a geometric window of variable size. Only those electron populations situated on field lines that pass through this window can be transported to the region where high density conics normally form. Critical field lines for the plasma behaviour are identified by increasing the size of the geometric window while concurrently measuring the conics density and ion beam characteristics. A step change in the beam velocity is observed when high density conics are able to fully reform. The field lines responsible for full conics formation are found to be those that pass within ∼2 skin depths of the source chamber wall. As such, the downstream plasma behaviour is dominated by electrons situated on field lines that are most effectively heated by the radio-frequency antenna and escape the source.
Some Implications of a Scale-Invariant Model of Statistical Mechanics to Classical and Black Hole Thermodynamics.

Some implications of a scale invariant model of statistical mechanics to the mechanical theory of heat of Helmholtz and Clausius are described. Modified invariant definitions of heat and entropy are presented closing the gap between radiation and gas theory. Modified relativistic transformations of pressure, Boltzmann constant, entropy, and density are introduced leading to transformation of ideal gas law. Following Helmholtz, the total thermal energy of thermodynamic system is decomposed into free heat U and latent heat p V and identified as modified form of the first law of thermodynamics Q = H = U + p V. Subjective versus objective aspects of Boltzmann thermodynamic entropy versus Shannon information entropy are discussed. Also, modified thermodynamic properties of ideal gas are presented. The relativistic thermodynamics being described is in accordance with Poincare - Lorentz dynamic theory of relativity as opposed to Einstein kinematic theory of relativity since the former theory that is based on compressible ether of Planck is causal as was emphasized by Pauli.
Marginal Zone B (MZB) Cells: Comparison of the Initial Identification of Immune Activity Leading to Dacryoadenitis and Sialadenitis in Experimental Sjögren’s Syndrome

Although multiple mouse strains have been advanced as models for Sjögren’s syndrome (SS), which is a human systemic autoimmune disease characterized primarily as the loss of lacrimal and salivary gland functions, the C57BL/6.NOD-Aec1Aec2 recombinant inbred (RI) mouse derived from the NOD/ShiLtJ line is considered one of the more appropriate models exhibiting virtually all the characteristics of the human disease. This mouse model, as well as other mouse models of SS, have shown that B lymphocytes are essential for the onset and development of observed clinical manifestations. Recently, studies carried out in the C57BL/6. IL14α transgenic mouse have provided clear evidence that the marginal zone B (MZB) cell population is directly involved in the early pathological events initiating the development of the clinical SS disease, as well as late-stage lymphomagenesis resulting in B-cell lymphomas. Since MZB cells are difficult to study in vivo and in vitro, we carried out a series of ex vivo investigations that utilize temporal global RNA transcriptomic analyses to profile differentially expressed genes exhibiting temporal upregulation during the initial onset and subsequent development of pathophysiological events within the lacrimal and salivary gland tissues per se or associated with the leukocyte cell migrations into these glands. The initial transcriptomic analyses revealed that while the upregulated gene expression profiles obtained from lacrimal and salivary glands overlap, multiple genetic differences exist between the defined activated pathways. In the current study, we present a concept suggesting that the initial pathological events differ between the two glands, yet the subsequent upregulated TLR4/TLR3 signal transduction pathway that activates the type-1 interferon signature appears to be identical in the two glands and indicates an autoimmune response against dsRNA, possibly a virus. Here, we attempt to put these findings into perspective and determine how they can impact the design of future therapeutic protocols.
Localizing graphene at the interface of cocontinuous polymer blends: Morphology, rheology, and conductivity of cocontinuous conductive polymer composites

Interfacial localization of graphene in cocontinuous polymer blends is shown to be effective in stabilizing the cocontinuous morphology and increasing conductivity with a low electrical percolation threshold. We created polylactic acid (PLA) and polystyrene (PS) cocontinuous blends filled with thermally reduced graphene oxide (r-GO) localized at the interface. The resulting conductive composites show dramatically improved conductivity at low filler loadings and an ultralow percolation threshold of 0.028 vol. %. We systematically studied the changes of conductivity and rheology of the PLA-PS composites during annealing. We found that r-GO transfers from the PLA phase to the interface during melt compounding and annealing and forms a spanning 3D network, which effectively suppresses the coarsening of the cocontinuous structure. Our study demonstrated that the 3D r-GO network significantly increases the conductivity and the storage modulus of the melt blends. Finally, we constructed a simple model, which qua.