Miracle-dz/UniFAR-FTUs huggingface dataset:
Forest rehabilitation in Vietnam: histories, realities and future

This report assesses the experiences of forest rehabilitation in Vietnam and draws strategic lessons from these experiences to guide new forest rehabilitation projects. The report highlights lessons from Vietnam's experiences that will be helpful beyond the country border. This report has the following structure: the remainder of chpater one provides the conceptual clarification and theoritical underpinnings for the study and introduces the methodology. Chapter two provides background information and context for the outcomes of forest rehabilitation in Vietnam, including basic information on Vietnam, its forest cover, forestry sector and policies that are relevant to forestry and forest rehabilitation. Chapter three gives an overview of forest rehabilitation in Vietnam from its inception in the 1950s until today, as the country carries out its latest nationwide forest rehabilitation effort, the 5 million hectares reforestation project. Chapter four analyses in detail forest rehabilitation project that were analysed in the field study carried out as part of this study. Chapter five draws lessons from the report.
Resection of the extravertebral portion of the filum terminale with posterior internal sphincterotomy, a surgical technique for managing chronic constipation and encopresis in children

Background: Constipation is a frequent digestive complaint in children and can be refractory to treatment in approximately 30% of patients. Etiologies that are linked to this pathology include rectal hyporeflexia, achalasia of the internal anal sphincter, and neurological disorders such as tight filum terminale syndrome. For these conditions, the resection of the extra vertebral portion of the filum terminale and posterior internal sphincterotomy has shown potential benefits for management. Methods: We conducted a cross-sectional descriptive study between 2020 and 2021. We collected data from 219 children's medical records at Saint Petersburg State Pediatric Hospital, Russia, that fulfilled the diagnostic criteria and were managed surgically. We analyze their demographic characteristics and clinical outcomes. Results: We found that 83.6% (n=183) of participants showed improvement, while 16.4% (n=36) experienced no improvement or complications. Patients in the 16-17 age group had the highest proportion of lack of improvement or complications, with 12.8% and the 1-5 age group exhibited a 100% improvement rate. Male patients exhibited a decreased probability of experiencing complications in the postoperative period.Conclusion: Resection of the extravertebral portion of the filum terminale with posterior internal sphincterotomy has shown potential benefits in managing chronic constipation and encopresis in pediatric patients. However, further research is warranted to investigate the benefits and risks of this surgical technique.
Repositioning of HMG-CoA Reductase Inhibitors as Adjuvants in the Modulation of Efflux Pump-Mediated Bacterial and Tumor Resistance

Efflux pump (EP)-mediated multidrug resistance (MDR) seems ubiquitous in bacterial infections and neoplastic diseases. The diversity and lack of specificity of these efflux mechanisms raise a great obstacle in developing drugs that modulate efflux pumps. Since developing novel chemotherapeutic drugs requires large investments, drug repurposing offers a new approach that can provide alternatives as adjuvants in treating resistant microbial infections and progressive cancerous diseases. Hydroxy-methyl-glutaryl coenzyme-A (HMG-CoA) reductase inhibitors, also known as statins, are promising agents in this respect. Originally, statins were used in the therapy of dyslipidemia and for the prevention of cardiovascular diseases; however, extensive research has recently been performed to elucidate the functions of statins in bacterial infections and cancers. The mevalonate pathway is essential in the posttranslational modification of proteins related to vital eukaryotic cell functions. In this article, a comparative review is given about the possible role of HMG-CoA reductase inhibitors in managing diseases of bacterial and neoplastic origin. Molecular research and clinical studies have proven the justification of statins in this field. Further well-designed clinical trials are urged to clarify the significance of the contribution of statins to the lower risk of disease progression in bacterial infections and cancerous diseases.
Proposal for a Distraction Technique Using Two-Screen Projection for Stress Relief in Children With Medical Complexity

The aim of this paper is to investigate the potential of virtual reality images as a means of reducing pain and fear in children, through the use of projection technology. While body-worn immersive displays have been previously suggested for this purpose, head-mounted displays have been found to be unsuitable due to their lack of interactivity. To address this issue, we propose a simple and cost-effective two-screen projection system that can be installed in a hospital room without interfering with communication and without compromising the immersive experience. By projecting onto screens installed on the wall and floor, an immersive digital space can be created visually. Our experiments, in which we measured $\alpha $ -amylase activity in saliva, showed that the proposed two-screen projection significantly reduced stress levels in healthy adults when compared to one-screen projection. Additionally, we conducted an experiment using the KOKORO scale as a subjective measure, which revealed that children with medical complexity experienced a significant reduction in stress levels after viewing the two-screen projection compared to before viewing. These findings suggest that the proposed system could serve as an ideal distraction in pediatric nursing, thereby providing much-needed nursing support to children and their families.
Erinaceus coronavirus persistence in hedgehogs (Erinaceus europaeus) in a non-invasive, in vivo, experimental setting

In the last 20 years, new zoonotic CoV strains have emerged (SARS-CoV, MERS-CoV, and SARS-CoV-2), and new species have also been reported in animals. In Europe, the Erinaceus coronavirus (EriCoV) was recently described in Erinaceus europaeus. However, information on the prevalence and duration of viral shedding is unknown. In this study, feces samples were collected from 102 European hedgehogs hosted in the Center for the Recovery of Wild Fauna in Rome and analyzed for the presence of EriCoV RNA by Reverse Transcription-PCR. In total, 45 animals (44.1%) resulted positive for EriCoV at the first sampling and 63 (61.7%) animals were positive at the follow-up, which was performed from the 3rd to the 86th day. The duration of fecal virus shedding showed a mean duration of 22.8 days and lasted up to 62 days. Eighteen hedgehogs showed intermittent viral shedding. Phylogenetic analysis showed a correlation with EriCoV strains reported in Germany, the United Kingdom, and northern Italy. None of the EriCoV sequences showed the CD200 ortholog insertion, previously observed in strains isolated in animals from northern Italy. Interestingly, all but one animal revealed the presence in their feces of the same EriCoV sequences, analyzing the short genomic region at 3' spike gene and 5' ORF3a 500bp fragment (100% nt.id.) in both first and follow-up samples. This result suggests that animals were infected with the same strain during their stay at the center. Our results confirm that EriCoV can persist in hedgehogs for a long period, underlining that hedgehogs are an important commensal reservoir for Merbecovirus. A long duration of viral shedding increases the likelihood that the virus will spread in the environment.
Oral Infection, Oral Pathology and Salivary Diagnostics of Mpox Disease: Relevance in Dentistry and OMICs Perspectives

In this narrative review, we aim to point out the close relationship between mpox virus (MPXV) infection and the role of saliva as a diagnostic tool for mpox, considering the current molecular approach and in the perspective of OMICs application. The MPXV uses the host cell’s rough endoplasmic reticulum, ribosomes, and cytoplasmic proteins to replicate its genome and synthesize virions for cellular exit. The presence of oral mucosa lesions associated with mpox infection is one of the first signs of infection; however, current diagnostic tools find it difficult to detect the virus before the rashes begin. MPXV transmission occurs through direct contact with an infected lesion and infected body fluids, including saliva, presenting a potential use of this fluid for diagnostic purposes. Currently available diagnostic tests for MPXV detection are performed either by real-time quantitative PCR (RT-qPCR) or ELISA, which presents several limitations since they are invasive tests. Despite current clinical trials with restricted sample size, MPXV DNA was detected in saliva with a sensitivity of 85%–100%. In this context, the application of transcriptomics, metabolomics, lipidomics, or proteomics analyses coupled with saliva can identify novel disease biomarkers. Thus, it is important to note that the identification and quantification of salivary DNA, RNA, lipid, protein, and metabolite can provide novel non-invasive biomarkers through the use of OMICs platforms aiding in the early detection and diagnosis of MPXV infection. Untargeted mass spectrometry (MS)-based proteomics reveals that some proteins also expressed in saliva were detected with greater expression differences in blood plasma when comparing mpox patients and healthy subjects, suggesting a promising alternative to be applied in screening or diagnostic platforms for mpox salivary diagnostics coupled to OMICs.
The Factors Influencing Behavioural Intention Fintech Lending (Paylater) Among Generation Z Indonesian Muslims and Islamic Consumption Ethics Views

This study seeks to investigate and analyze the factors that influence Generation Z’s use of fintech lending (paylater) in Jakarta, West Java, East Java, Central Java, and North Sumatra. This study employs a descriptive quantitative methodology and questionnaire distribution. The study employed purposive sampling. This study included 200 Generation Z respondents who have utilized fintech lending (paylater) as respondents. The method of data analysis employs Partial Least Square-Structural Equation Modeling (PLS-SEM) and SmartPLS version 3.2. 9 software. The variables performance expectation, social influence, hedonic motivation, and habit have a positive and significant effect on behavioral intention, whereas effort expectation, facilitating conditions, and price value do not. In addition to testing the UTAUT 2 model, this research was conducted on Generation Z, where few research results are discussing the use of fintech lending (paylater). Generation Z is the generation that currently dominates the population in Indonesia and will be the next generation of Indonesians; therefore, it is essential to determine what factors play a role in encouraging the use of fintech lending (paylater) among Generation Z.AbstrakPenelitian ini tujuannya guna menyelidiki serta menganalisis faktor-faktor yang pengaruhi pemakaian fintech lending (paylater) generasi Z di Jakarta, Jawa Barat, Jawa Timur, Jawa Tengah, dan Sumatera Utara. Penelitian ini menggunakan metodologi kuantitatif deskriptif dan penyebaran kuesioner. Penelitian ini menggunakan purposive sampling. Penelitian ini melibatkan 200 responden generasi Z yang telah memanfaatkan fintech lending (paylater) sebagai responden. Metode analisis data memakai perangkat lunak PLS-SEM dan SmartPLS versi 3.2. 9. Variabel ekspektasi kinerja, pengaruh sosial, motivasi hedonis, serta kebiasaan berpengaruh positif juga signifikan pada niat berperilaku, sedangkan ekspektasi upaya, kondisi fasilitasi, dan nilai harga tidak. Selain menguji model UTAUT 2, penelitian ini dilakukan pada generasi Z, dimana hasil penelitian yang membahas tentang penggunaan fintech lending (paylater) masih sedikit. Generasi Z merupakan generasi yang sekarang mendominasi jumlah penduduk di Indonesia dan akan menjadi generasi penerus bangsa Indonesia; Maka dari itu, penting agar tau faktor apa saja yang berperan untuk mendorong penggunaan fintech lending (paylater) di kalangan generasi Z.
Work-life balance, social support, and burnout: A quantitative study of social workers

Summary: Stress in social work is frequently experienced by practitioners and is attributed to a range of work-related factors. This study explored the manifestation of burnout, perceived social support, and work-life balance in 73 social workers in two cities in south India. A cross-sectional quantitative design was used. Data were collected based on survey methodology and three standardized instruments were administered to assess the manifestation of our key variables. Multiple regression analysis was used to identify the predictors of burnout. Findings: Results indicated high levels of burnout and low levels of social support and work-life balance in respondents. No significant differences were seen in the key variables of the study based on selected sociodemographic factors. Both social support and work-life balance were extracted as significant predictors of burnout. Application: We suggest that issues related to burnout and compassion fatigue are key aspects that need to be incorporated within the social work curriculum in educational programs in India. A focus on maintaining a healthy work-life balance, and the importance of self-care in maintaining good health and wellbeing are key elements that need to be emphasized. We make use of the literature to offer suggestive measures that can be taken to enhance the provision of social support, maintain better work-life balance and reduce the incidence of burnout in social work practitioners. This will in the long run bode well for the mental health and wellbeing of the professionals besides ensuring better quality of service provision to the community that they work with.
Stock market reaction to the military conflict between Russia and Ukraine: an event study for the European tourism and hospitality industry

ABSTRACT This paper examines the short-term market reaction of European tourism and hospitality industry to the beginning of the military conflict between Russia and Ukraine (24 February 2022). Using an event study, for a sample of 165 listed firms, we observe a negative and statistically significant stock price reaction at and around the beginning of the military conflict between Russia and Ukraine. These results are consistent with investor sentiment hypothesis and asset-pricing perspective. These reactions are reinforced or mitigated by firm-specific characteristics such as liquidity, size, profitability, and institutional ownership. Finally, we find that listed firms located in: (i) countries in which Russia and Ukraine are the largest source of inbound foreign tourists, and (ii) countries formerly occupied by the Soviet Union and/or that share a common border with Russia, tend to show more negative abnormal returns.
Nonlinear Relationship Between Interleukin-6 and NT-proBNP at Admission in Hospitalized COVID-19 Patients

Purpose Elevated levels of the inflammatory marker interleukin-6 (IL-6) and cardiac injury marker N-terminal pro-B-type natriuretic peptide (NT-proBNP) have been observed in patients with coronavirus disease 2019 (COVID-19). However, the relationship between IL-6 and NT-proBNP levels remains unclear. Therefore, we investigated the relationship between IL-6 and NT-proBNP levels in patients with COVID-19. Patients and Methods This was a cross-sectional study. Consecutive patients with COVID-19 were included herein. The independent and dependent target variables were the IL-6 and NT-proBNP levels, respectively, measured at baseline. Univariate and multivariate linear regression analyses and curve fitting were also performed. Results The average age of the 121 selected participants was 49.8 ± 15.8 years old, and 48.8% (59/121) were male. The estimated β value between Ln-transformed IL-6 and NT-proBNP was 0.28 (95% confidence interval [CI] 0.12–0.44, P = 0.001) in univariate logistic regression analysis and 0.09 (95% CI −0.04–0.21, P = 0.176) in the fully adjusted model. This relationship was nonlinear, with a point of 2.7, and the β values (and CIs) for the left (<2.7) and right (≥2.7) sides of the inflection point were −0.06 (95% CI −0.23–0.12, P = 0.534) and 0.77 (95% CI 0.18–1.37, P = 0.016) in the fully adjusted model, respectively. Conclusion Our results suggest a nonlinear association between IL-6 and NT-proBNP levels. Higher IL-6 levels are associated with NT-proBNP in patients with COVID-19.
Effect of Previous Coronavirus Disease 2019 Infection on Patients Undergoing Open-Heart Surgery

Objectives: This study aimed to evaluate the effects of previous coronavirus disease 2019 (COVID-19) infection on mortality, factors influencing mortality, and potential postoperative complications in on-pump cardiac surgery. Methods: This single-center, retrospective, observational study included 233 adult patients who underwent on-pump cardiac surgery between June 2021 and February 2022. Patients with preoperative history of COVID-19 infection confirmed by nasopharyngeal swab polymerase chain reaction (PCR) test were compared to those without COVID-19 history. Results: Patients’ mean age was 60.12±11.26 years (range, 23–81 years), and 77.3% were male. The mean time from PCR positivity to surgery was 191.11±169.9 days (median, 108 days). No between-group differences were observed in anesthesia, cross-clamp time, pump time, operative time, extubation time, length of intensive care unit and hospital stay, or mortality (p>0.05). The post-COVID-19 group had higher rates of preoperative acute neurologic events and arrhythmias, pump lactate levels, and intraoperative inotropic scores (p<0.05). These factors were not associated with survival. Postoperative pneumothorax was more frequent in the post-COVID-19 group (p=0.002) and associated with longer length of hospital stay. No significant difference was observed in preoperative, postoperative, or changes in neutrophil/lymphocyte ratio (NLR) between groups. Conclusion: Patients with and without COVID-19 history had similar outcomes after open-heart surgery. Nevertheless, the former had increased frequency of postoperative pneumothorax and prolonged length of hospital stay. Open-heart surgery seems safe after COVID-19. However, larger, prospective studies including inflammatory markers other than NLR are needed to further investigate the potential complications.
Diversity of the Microbiota of Traditional Izmir Tulum and Izmir Brined Tulum Cheeses and Selection of Potential Probiotics

High-throughput DNA sequencing (HTS) was used to study the microbial diversity of commercial traditional Izmir Tulum (IT) and Izmir Brined Tulum (IBT) cheeses from Izmir, Türkiye. Simultaneously, cultivation-dependent methods were used to isolate, identify and characterize bacterial strains displaying probiotic potential. At the phylum level, Firmicutes dominated the microbiota of both cheese types comprising >98% of the population. Thirty genera were observed, with Streptococcus being the most abundant genus and with Streptococcus thermophilus and S. infantarius subsp. infantarius being the most abundant species. Genera, including Bifidobacterium and Chryseobacterium, not previously associated with IT and IBT, were detected. IT cheeses displayed higher operational taxonomic units (OTUs; Richness) and diversity index (Simpson) than IBT cheeses; however, the difference between the diversity of the microbiota of IT and IBT cheese samples was not significant. Three Lacticaseibacillus paracasei strains isolated from IBT cheeses exhibited probiotic characteristics, which included capacity to survive under in vitro simulated gastrointestinal conditions, resistance to bile salts and potential to adhere to HT-29 human intestinal cells. These findings demonstrate that Tulum cheeses harbor bacterial genera not previously reported in this cheese and that some strains display probiotic characteristics.
Characterizing Bodyweight-Supported Treadmill Walking on Land and Underwater Using Foot-Worn Inertial Measurement Units and Machine Learning for Gait Event Detection

Gait rehabilitation commonly relies on bodyweight unloading mechanisms, such as overhead mechanical support and underwater buoyancy. Lightweight and wireless inertial measurement unit (IMU) sensors provide a cost-effective tool for quantifying body segment motions without the need for video recordings or ground reaction force measures. Identifying the instant when the foot contacts and leaves the ground from IMU data can be challenging, often requiring scrupulous parameter selection and researcher supervision. We aimed to assess the use of machine learning methods for gait event detection based on features from foot segment rotational velocity using foot-worn IMU sensors during bodyweight-supported treadmill walking on land and underwater. Twelve healthy subjects completed on-land treadmill walking with overhead mechanical bodyweight support, and three subjects completed underwater treadmill walking. We placed IMU sensors on the foot and recorded motion capture and ground reaction force data on land and recorded IMU sensor data from wireless foot pressure insoles underwater. To detect gait events based on IMU data features, we used random forest machine learning classification. We achieved high gait event detection accuracy (95–96%) during on-land bodyweight-supported treadmill walking across a range of gait speeds and bodyweight support levels. Due to biomechanical changes during underwater treadmill walking compared to on land, accurate underwater gait event detection required specific underwater training data. Using single-axis IMU data and machine learning classification, we were able to effectively identify gait events during bodyweight-supported treadmill walking on land and underwater. Robust and automated gait event detection methods can enable advances in gait rehabilitation.