Miracle-dz/UniFAR-FTUs huggingface dataset:
ORAL OR INJECTABLE ALOE VERA? APPROACHES FOR TREATING GINGIVITIS ASSOCIATED WITH LIGATURE INDUCED PERIODONTITIS IN WISTAR RATS

Periodontitis is a set of inflammatory diseases affecting the periodontium, and the tissues that surround and support the teeth. Mouthwash solutions are mainly used for their antiseptic properties. They currently include synthetic agents, or essential oils. Many natural extracts may also be used, these associate both antiseptic effects and action on host response, due to their antioxidant, immunoregulatory, and analgesic, buffering, or healing properties. The best known are avocado oil, manuka oil, propolis oil, grapefruit seed extract, pycnogenol, Aloe Vera, Q10 coenzyme, green tea, and megamin. AIM: The aim of this study is to assess and compare between the Oral and systemic administration of Aloe Vera on gingivitis Associated with induced periodontits in male Wistar rat. METHODS: Forty adult male Wistar rats with an average weight 150-250 g, 6–7 weeks old were will be assigned to the ligature, and divided randomly into four groups with 10 rats in each group: The first group (control) were daily intraperitoneally injected with saline (5mg/kg). The rats of the second group were given Aloe Vera extract intraperitoneally (300mg/kg) starting one day before ligature and continuing for one month. The rats in the third group were given saline (5mg/kg) orally, while rats in the fourth group were given Aloe Vera extract (300mg/kg) by oral gavage starting one day before ligature and continuing for one month. At the end of 30 days for all groups, all animals were sacrificed, the gingiva was dissected, processed, and a set of sections were stained with haematoxylin and eosin for detection of any morphological changes. The other two sets of sections were labeled for localization of PCNA and caspase-3. The epithelial thickness was measured, and the data were calculated, analyzed and computed to compare the two routes of administration on the induced periodontitis. RESULTS: There was a high significant difference between all groups in their epithelial thickness measurements and high significant difference between the oral and control groups. The immunohistochemistry revealed that there was an overall high significant difference in the PCNA and caspase-3 area% between the studied groups. In addition there has been a high significant increase the PCNA reaction in the oral and intraperitoneal groups versus the control group, while in caspase-3 immunostaining there has been a statistically significant increase in the control group versus both the oral and the peritoneal groups.
Validation of Soil Phosphate Removal by Alkaline and Acidic Reagents in a Vertosol Soil using XANES Spectroscopy

There is a paucity of information on the soil phosphorus (P) forms removed by alkaline and acidic reagents in Vertosols. The first aim of this study was to identify which soil phosphates are removed by a two-step sequential fractionation (0.1 M NaOH and 1 M HCl) and by a dilute acid extractant (0.005 M H2SO4; Bureau of Sugar Experiment Stations (BSES) soil P test) on an “untreated” Vertosol using P K-edge x-ray absorption near-edge structure (XANES) at the Australian Synchrotron. There was supporting evidence that the 0.1 M sodium hydroxide (NaOH), 1 M hydrochloric acid (HCl), and 0.005M sulfuric acid (H2SO4) extractants remove soil phosphates according to the chemical solubility of known P minerals. The XANES spectra revealed the 1 M HCl and 0.005 M H2SO4 extractants remove calcium (Ca) phosphates from Vertosols, suggesting the latter extractant could be used as an alternative for a rapid and cost-effective measure of Ca phosphates in Vertosols.
Magnetization reversal and Yb3+/Cr3+ spin ordering at low temperature for perovskite YbCrO3 chromites

The temperature dependence of the dc magnetization and the specific heat capacity are systematically investigated for the perovskite YbCrO3 chromites. The results show that there exist two complex sequences of magnetic transitions with the characteristics of magnetization reversal and Yb3+/Cr3+ spin ordering at different temperature, respectively. The antiferromagneticlike transition around TN=118 K is attributed to the antiferromagnetic ordering of the Cr3+ spins and a negative magnetization, accompanied with a tendency to the plateau below 10 K caused by the Yb3+ ordering. We obtain the Weiss constant of −197.0 K and an effective moment of 5. 99μB for the sum of the free ion values of 4. 53μB for Yb3+ and 3. 87μB for high-spin Cr3+ from the experiments, which shows an antiferromagnetic interaction and the existence of weak canted antiferromagnetic (CAFM) characteristics. Corresponding to the magnetic phase transition in the Cr sublattice, the specific heat capacity under zero fields exhibits a sharp λ-shap.
Clinical Assessment of Breast Volume: Can 3D Imaging Be the Gold Standard?

Background: Three-dimensional (3D) camera systems are increasingly used for computerized volume calculations. In this study we investigate whether the Vectra XT 3D imaging system is a reliable tool for determination of breast volume in clinical practice. It is compared with the current gold standard in literature, magnetic resonance imaging (MRI), and current clinical practice (plastic surgeon’s clinical estimation). Methods: Breast volumes of 29 patients (53 breasts) were evaluated. 3D images were acquired by Vectra XT 3D imaging system. Pre-existing breast MRI images were collected. Both imaging techniques were used for volume analyses, calculated by two independent investigators. Breast volume estimations were done by plastic surgeons during outpatient consultations. All volume measurements were compared using paired samples t-test, intra-class correlation coefficient, Pearson’s correlation, and Bland–Altman analysis. Results: Two 3D breast volume measurements showed an excellent reliability (intra-class correlation coefficient: 0.991), which was comparable to the reliability of MRI measurements (intra-class correlation coefficient: 0.990). Mean (SD) breast volume measured with 3D breast volume was 454 cm3 (157) and with MRI was 687 cm3 (312). These volumes were significantly different, but a linear association could be found: y(MRI) = 1.58 × (3D) – 40. Three-dimensional breast volume was not significantly different from volume estimation made by plastic surgeons (472 cm3 (69), P = 0.323). Conclusions: The 3D imaging system measures lower volumes for breasts than MRI. However, 3D measurements show a linear association with MRI and have excellent reliability, making them an objective and reproducible measuring method suitable for clinical practice.
Potential Therapeutic Role of Purinergic Receptors in Cardiovascular Disease Mediated by SARS-CoV-2

Novel coronavirus disease 2019 (COVID-19) causes pulmonary and cardiovascular disorders and has become a worldwide emergency. Myocardial injury can be caused by direct or indirect damage, particularly mediated by a cytokine storm, a disordered immune response that can cause myocarditis, abnormal coagulation, arrhythmia, acute coronary syndrome, and myocardial infarction. The present review focuses on the mechanisms of this viral infection, cardiac biomarkers, consequences, and the possible therapeutic role of purinergic and adenosinergic signalling systems. In particular, we focus on the interaction of the extracellular nucleotide adenosine triphosphate (ATP) with its receptors P2X1, P2X4, P2X7, P2Y1, and P2Y2 and of adenosine (Ado) with A2A and A3 receptors, as well as their roles in host immune responses. We suggest that receptors of purinergic signalling could be ideal candidates for pharmacological targeting to protect against myocardial injury caused by a cytokine storm in COVID-19, in order to reduce systemic inflammatory damage to cells and tissues, preventing the progression of the disease by modulating the immune response and improving patient quality of life.
Variability of breaking the surface tension of the droplet adjuvant (Aureo®) as a function of local water catchment.

When added the adjuvant in plant protection products, can print the desirable characteristics spray solution, how to reduce the surface tension in aqueous solutions, enabling greater contact with the surface of the syrup plant and reduce the potential for drift during spraying. The objective of this study was to evaluate the behavior of the surface tension drops of solution prepared with 2,4-D at different concentrations (0, 0.05, 0.1, 0.2 and 0.4% spray volume ) of adjunctive methyl ester of soybean oil (Aureo ®). The water used for evaluation was collected in 10 community water supply in different regions of western Paraná. In the laboratory performed the weighing of the droplets formed at the end of a burette, with four repetitions. Data were submitted to ANOVA, the locations compared by the Tukey test at 5% and the rates submitted to regression. Significant responses (P <0.05) to increasing doses of the adjuvant and the adjuvant action for different sampling sites of water. The results showed had variability in the response of spray solution to break the surface tension as a function of the adjuvant catchment water spray. The efficiency of the maximum dose of adjuvant Aureo ® to break the surface tension of water was 0,26% of the volume of water in the region studied.
Bioactive Saponins and Glycosides. Part 29

Three new acylated oleanane-type triterpene saponins, theasaponins A6 (1), A7 (2), and B5 (3), were isolated from the saponin fraction of the seeds of the Japanese tea plant Camellia sinensis together with the known constituent foliatheasaponin III (4). The structures of the glycosides 1–3 were elucidated on the basis of spectroscopic, chemical, and physico-chemical evidence.
Quasiparticle and thermodynamic mass in the heavy-fermion system CeB6

The de Haas-van Alphen effect has been investigated in the heavy-fermion compound CeB6 in magnetic fields extending to 53 T. Absolute amplitude measurements reveal that the major sheets of the Fermi surface are not spin polarized, and that its observed volume is 1.15+or-0.1 electrons per formula unit. Analysis of the field dependence of the quasiparticle effective mass based on the periodic Anderson model yields, for the ratio of the characteristic temperature to the g factor, T*/g = 4.0 +or- 0.8 K, while over the field interval 31-43 T, for which the mass changes by a factor of two, the mean free path of the quasiparticles remains constant at 56 +or- 1 nm. We compare the density of states derived from the measured quasiparticle masses with that deduced from specific-heat experiments for magnetic fields below approximately 30 T, and find them to be in agreement. We conclude that the low-temperature thermodynamics of CeB6 may be understood simply in terms of the low-energy excitations of a heavy charged Fermi liquid. We note that these experiments do not support the idea of Kagan et al that a significant contribution to the low-temperature thermodynamics of Ce-based heavy-fermion systems arises from the presence in them of a neutral Fermi liquid.
Development of Pop Up Book Media Material Distinguishing Characteristics of Healthy and Unfit Environments Class III Students Elementary School

This research is based on the observation in the third grade of Natural Science (IPA) subject matter of healthy and unhealthy environment characteristic, that most of students have difficulty in learning because the teacher uses conventional teaching method. In addition, the use of learning media is considered less maximized by teachers. This research is research and development (R & D) with model of ADDIE development. Stages there are 5 stages namely 1) Analysis (Analysis), Development (Design), Implementation (Implementation), Evaluation (Evaluation). Validation is done by material experts, media experts, and classroom teachers. The conclusion of this research is (1) Result of Development of Pop Up Book media with material to distinguish the characteristics of healthy and unhealthy environment Valid. (2) The teacher's response to the learning media of Pop Up Book that was developed, after being used in learning material, characteristic of healthy and unhealthy environment obtained good response. Likewise the response of students to this media get a positive response. (3) Pop Up Book media characteristics of a healthy and unhealthy environment based on the overall assessment of the percentage of assessment is in the category of very appropriate to be used as a medium of learning Natural Science for grade 3 primary school students. Based on the conclusions of this study, recommended: (1) for teachers, one of the media that can be used in supporting the learning process is Pop Up Book, can help students become more active and can create a fun class atmosphere. (2) For further research, trials should be conducted more widely, so as to produce a widely used learning medium. Copyright © Universitas Pendidikan Ganesha. All rights reserved. A R T I C L E I N F O Article history: Received 15 Desember 2017 Received in revised form 28 Desember 2017 Accepted 17 Januari 2018 Available online 20 Februari 2018 Kata Kunci: Media Buku Pop Up , Lingkungan Sehat dan Tidak Sehat
Application of Distributed Parameter Model to Assessment of Glioma IDH Mutation Status by Dynamic Contrast-Enhanced Magnetic Resonance Imaging

Previous studies using contrast-enhanced imaging for glioma isocitrate dehydrogenase (IDH) mutation assessment showed promising yet inconsistent results, and this study attempts to explore this problem by using an advanced tracer kinetic model, the distributed parameter model (DP). Fifty-five patients with glioma examined using dynamic contrast-enhanced imaging sequence at a 3.0 T scanner were retrospectively reviewed. The imaging data were processed using DP, yielding the following parameters: blood flow F, permeability-surface area product PS, fractional volume of interstitial space Ve, fractional volume of intravascular space Vp, and extraction ratio E. The results were compared with the Tofts model. The Wilcoxon test and boxplot were utilized for assessment of differences of model parameters between IDH-mutant and IDH-wildtype gliomas. Spearman correlation r was employed to investigate the relationship between DP and Tofts parameters. Diagnostic performance was evaluated using receiver operating characteristic (ROC) curve analysis and quantified using the area under the ROC curve (AUC). Results showed that IDH-mutant gliomas were significantly lower in F (P = 0.018), PS (P < 0.001), Vp (P < 0.001), E (P < 0.001), and Ve (P = 0.002) than IDH-wildtype gliomas. In differentiating IDH-mutant and IDH-wildtype gliomas, Vp had the best performance (AUC = 0.92), and the AUCs of PS and E were 0.82 and 0.80, respectively. In comparison, Tofts parameters were lower in Ktrans (P = 0.013) and Ve (P < 0.001) for IDH-mutant gliomas. No significant difference was observed in Kep (P = 0.525). The AUCs of Ktrans, Ve, and Kep were 0.69, 0.79, and 0.55, respectively. Tofts-derived Ve showed a strong correlation with DP-derived Ve (r > 0.9, P < 0.001). Ktrans showed a weak correlation with F (r < 0.3, P > 0.16) and a very weak correlation with PS (r < 0.06, P > 0.8), both of which were not statistically significant. The findings by DP revealed a tissue environment with lower vascularity, lower vessel permeability, and lower blood flow in IDH-mutant than in IDH-wildtype gliomas, being hostile to cellular differentiation of oncogenic effects in IDH-mutated gliomas, which might help to explain the better outcomes in IDH-mutated glioma patients than in glioma patients of IDH-wildtype. The advantage of DP over Tofts in glioma DCE data analysis was demonstrated in terms of clearer elucidation of tissue microenvironment and better performance in IDH mutation assessment.
The Impact of Electroacupuncture at Hegu, Shousanli, and Quchi Based on the Theory “Treating Flaccid Paralysis by Yangming Alone” on Stroke Patients' EEG: A Pilot Study

Background In China, electroacupuncture based on meridians theory “treating flaccid paralysis by Yangming alone” has been widely used for stroke rehabilitation in clinical practice. The aim of this study was to explore the electroencephalography change of electroacupuncture intervention on strokes patients with flaccid paralysis. Methods Twenty-three stroke patients with flaccid paralysis and six stroke patients with spasticity accepted electroacupuncture with the acupoints Hegu [LI4], Shousanli [LI10], and Quchi [LI11] for 20 minutes and their EEG data were recorded before, during, and after the electroacupuncture intervention. Results Compared with the baseline EEG signals before electroacupuncture, the ipsilesional and contralesional beta-band average power of patients with flaccid paralysis and spasticity were significantly increased during the needles retention stage and decreased slightly after removing the needles. The significant decrease of the ipsilesional and contralesional delta band average power in patients with flaccid paralysis occurred during the electroacupuncture stimulation, and they increased after the removal of the needles. The ipsilesional delta band average power of patients with spasticity significantly decreased during the electroacupuncture stimulation. Conclusion From this pilot electrophysiological study, we provided a possible electrophysiological mechanism of the curative effect of electroacupuncture for stroke rehabilitation.
Growth Rate Modulation Enables Coexistence in a Competitive Exclusion Scenario Between Microbial Eukaryotes

Coexistence usually are exceeding the explicable rate by competitive exclusion principle. Since the pioneer Gause, many studies have used protist microcosm systems to study competitive exclusion. We explored a two-species system with the testate-amoebae: (Arcella intermedia and Pyxidicula operculata), where competitive exclusion is expected to occur. We determined their growth curves individually and under competitive interaction. We used a state-space model to represent system dynamics and calculated posterior population sizes simulating competition dynamics. Contrarily to our expectation, Arcella and Pyxidicula showed similar growth rates (1.37 and 1.46 days–1 respectively) and only different carrying capacity (1,997 and 25,108 cells cm–2 respectively). The maximum number of cells of both species when growing in competition was much lower if compared to the monospecific cultures (in average, 73% and 80% less for Arcella and Pyxidicula respectively). However, our competition experiments always resulted in coexistence. According to the models, the drop in growth rates and stochasticity mainly explains our coexistence results. We propose that a context of ephemeral resources can explain these results. Additionally, we propose generating factors of stochasticity as intraspecific variation, small population effects, toxicity of waste products and influence of the bacterial community.
Comparison of mesoscopic phospholipid-water models

In this study we show how a coarse-grained model of a phospholipid can be developed and we study the parameter sets applied to the formation of a coarse-grained dimyristoyl phosphatidyl choline (DMPC) bilayer. We create a model comprising a head group of three hydrophilic beads, to which two hydrophobic tails are connected. From results obtained with molecular dynamics simulations on a single lipid in water, a bond-bending potential between three subsequent beads was added. Using a bead volume of 90 A3, we reproduce the experimental values of the area per lipid and the hydrophobic thickness. There is no linear relation between the repulsion parameter aij and the level of coarse graining. The key factor in the formation of a lipid bilayer is the difference between the water–water and the water–hydrophobic tail repulsion parameters.
A COMPUTATIONAL STUDY OF THE STRUCTURE, STABILITY, DYNAMICS, AND RESPONSE OF LOW STRETCH DIFFUSION FLAME

18 CHAPTER 1 . 20 1.1 Diffusion Flame Dynamics . 21 1.2 Radiation Effects. 26 1.3 Counterflow Diffusion Flame . 29 1.3. 1 Tsuji Type Flames. 30 1.3. 2 Opposed Jet Flames . 31 1.4 Low Stretch Diffusion Flames . 33 1.5 Flame Instabilities. 36 1.6 Edge Flames. 40 1.7 Low Stretch Diffusion Flame Instabilities. 42 1.8 Motivation. 44 1.9 Objectives . 46 CHAPTER 2 . 49 2.1 Planar Counterflow Configuration (PCC) . 50 2.2 Axisymmetric Counterflow Configuration (ACC) . 52 2.3 Radiation Modeling . 53 2.4 Problem Formulation . 55
Studies on Curing Kinetics Parameter of TDI-PPG-MOCA Polyurethane by FTIR

The curing process of polyurethanes was investigated with FTIR method. The curves of conversion (α)VS curing reaction time (t) at different temperatures were obtained . The curing reaction of the system was found to be second order reaction. The reaction rate constants and activation energy had been measured. Effect of the use lever of curing agent and temperatures on curing reaction was discussed. The results showed that when the mole ratio of NCO/OH is smaller than 1, the crosslinking reaction take place at high temperature.
Photochemical reactions of naproxen, ibuprofen and tylosin

He,Yang. M.S.E. , Purdue University, December, 2013. Photochemical reactions of Naproxen, Ibuprofen and Tylosin. Major Professor: Inez Hua. Pharmaceuticals and personal care products (PPCPs) include a wide range of compounds that are used extensively and sometimes daily by people. Some PPCPs have been detected in surface water (streams, rivers, lakes) due to incomplete removal in wastewater treatment plants. The water contaminated by PPCPs is harmful to aquatic organisms and human. Naproxen (NXP), ibuprofen (IBP) and tylosin (TYL) are chosen as representative PPCPs in the current research, because they are consumed in large quantities throughout the world and there is limited data about photodegradation of these compounds in aqueous solution at the wavelength of 254 nm. The combination of ultraviolet light (UV254nm) and hydrogen peroxide (H2O2) (UV/H2O2) degraded greater than 90% of the initial concentration of NXP and IBP within 3 min (k = 0.018 sec-1, k = 0.023 sec-1 for NXP and IBP, respectively). Under direct photolysis (UV254nm) and at pH = 7, 20 min of treatment was required to obtain 90% degradation (k = 0.0028 sec-1 for NXP, k = 0.0023 sec-1 for IBP). Under the same conditions, molar absorptivity (Ɛ) and quantum yield (ɸ) of each compound were determined (for NXP, Ɛ = 4240 M-1cm-1 and ɸ = 0.008; for IBP, Ɛ =299 M-1cm-1 and ɸ = 0.098). Overall, degradation rate constants increased with increasing initial H2O2 level (0 mM, 1mM and 3
Emulsifying properties of some legume proteins

Protein concentrates of some Nigerian underused legume seed flours, lima bean (Phaseolus lunatus L.) and pigeon pea (Cajanus cajan), were prepared by alkaline extraction followed by acid precipitation, whereas that of African yam bean (Sphenotilis sternocarpa) was prepared by acid extraction followed by alkaline precipitation. Simple and objective means that allowed precise determination of the inversion point were used in investigating the capacity of the protein concentrates to emulsify fat. Their relative efficiencies as emulsion stabilizers were also investigated. The results revealed that the emulsifying capacities of these protein concentrates decreased with increasing protein concentration and emulsifying speed. However, emulsifying capacities increased with increasing initial aliquot size, whereas variation of speed of oil addition did not have any significant influence. The capacity of the protein concentrates to emulsify fat decreased in the order pigeon pea protein concentrate > lima bean protein concentrate > African yam bean protein concentrate. But for emulsion stability, the protein concentrates were in the opposite rank order.