Miracle-dz/UniFAR-FTUs huggingface dataset:
A Wildly Flickering Jet in the Black Hole X-Ray Binary MAXI J1535–571

We report on the results of optical, near-infrared (NIR), and mid-infrared observations of the black hole X-ray binary candidate (BHB) MAXI J1535–571 during its 2017/2018 outburst. During the first part of the outburst (MJD 58004–58012), the source shows an optical–NIR spectrum that is consistent with an optically thin synchrotron power law from a jet. After MJD 58015, however, the source faded considerably, the drop in flux being much more evident at lower frequencies. Before the fading, we measure a dereddened flux density of ≳100 mJy in the mid-infrared, making MAXI J1535–571 one of the brightest mid-infrared BHBs known so far. A significant softening of the X-ray spectrum is evident contemporaneous with the infrared fade. We interpret it as being due to the suppression of the jet emission, similar to the accretion–ejection coupling seen in other BHBs. However, MAXI J1535–571 did not transition smoothly to the soft state, instead showing X-ray hardness deviations associated with infrared flaring. We also present the first mid-IR variability study of a BHB on minute timescales, with a fractional rms variability of the light curves of ∼15%–22%, which is similar to that expected from the internal shock jet model, and much higher than the optical fractional rms (≲7%). These results represent an excellent case of multiwavelength jet spectral timing and demonstrate how rich, multiwavelength time-resolved data of X-ray binaries over accretion state transitions can help in refining models of the disk–jet connection and jet launching in these systems.
Aeroelastic instability of cantilevered flexible plates in uniform flow

We address the flutter instability of a flexible plate immersed in an axial flow. This instability is similar to flag flutter and results from the competition between destabilizing pressure forces and stabilizing bending stiffness. In previous experimental studies, the plates have always appeared much more stable than the predictions of two-dimensional models. This discrepancy is discussed and clarified in this paper by examining experimentally and theoretically the effect of the plate aspect ratio on the instability threshold. We show that the two-dimensional limit cannot be achieved experimentally because hysteretical behaviour and three-dimensional effects appear for plates of large aspect ratio. The nature of the instability bifurcation (sub- or supercritical) is also discussed in the light of recent numerical results.
On the universal cover and the fundamental group of an RCD*(K,N)-space

The main goal of the paper is to prove the existence of the universal cover for {\mathsf{RCD}^{*}(K,N)}-spaces. This generalizes earlier work of [43, 44] on the existence of universal covers for Ricci limit spaces. As a result, we also obtain several structure results on the (revised) fundamental group of {\mathsf{RCD}^{*}(K,N)}-spaces. These are the first topological results for {\mathsf{RCD}^{*}(K,N)}-spaces without extra structural-topological assumptions (such as semi-local simple connectedness).
Observation of chirality transition of quasiparticles at stacking solitons in trilayer graphene

Trilayer graphene (TLG) exhibits rich novel electronic properties and extraordinary quantum Hall phenomena owning to enhanced electronic interactions and tunable chirality of its quasiparticles. Here, we report direct observation of chirality transition of quasiparticles at stacking solitons of TLG via spatial-resolved Landau level spectroscopy. The one-dimensional stacking solitons with width of the order of 10 nm separate adjacent Bernal-stacked TLG and rhombohedral-stacked TLG. By using high field tunneling spectra of scanning tunneling microscopy, we measured Landau quantization in both the Bernal-stacked TLG and the rhombohedral-stacked TLG and, importantly, we observed evolution of quasiparticles between the chiral degree l = 1&2 and l = 3 across the stacking domain wall solitons. Our experiment indicates that such a chirality transition occurs smoothly, accompanying the transition of the stacking orders of TLG, around the domain wall solitons. This result demonstrates the important and hitherto neglected relationship between the crystallographic stacking order and the chirality of quasiparticles in graphene systems.
Explaining the transient fast blue absorption lines in the massive binary system η Carinae

We use recent observations of the He i λ10 830 A absorption line and 3D hydrodynamical numerical simulations of the winds collision to strengthen the case for an orientation of the semimajor axis of the massive binary system η Carinae where the secondary star is toward us at periastron passage. These observations show that the fast blue absorption component exists for only several weeks prior to the periastron passage. We show that the transient nature of the fast blue absorption component supports a geometry where the fast secondary wind, both pre- and post-shock material, passes in front of the primary star near periastron passage.
THE HOST GALAXIES OF GAMMA-RAY BURSTS. II. A MASS–METALLICITY RELATION FOR LONG-DURATION GAMMA-RAY BURST HOST GALAXIES

We present a statistically robust mass–metallicity relation for long-duration gamma-ray burst (LGRB) host galaxies at z < 1. By comparing the LGRB host mass–metallicity relation to samples representative of the general star-forming galaxy population, we conclude that LGRBs occur in host galaxies with lower metallicities than the general population, and that this trend extends to z ∼ 1, with an average offset of −0.42 ± 0.18 from the M–Z relation for star-forming galaxies. Our sample in this work includes new spectroscopic data for six LGRB host galaxies obtained at the Keck and Magellan telescopes, as well as two new host galaxies from the literature. Combined with data from our previous work, this yields a total sample of six LGRB host galaxies at z < 0.3 and 10 host galaxies at 0.3 < z < 1. We have determined a number of interstellar medium properties for our host galaxies using optical emission-line diagnostics including metallicity, ionization parameter, young stellar population age, and star formation rate. Across our full sample of 16 LGRB hosts we find an average metallicity of log(O/H) + 12 = 8.4 ± 0.3. Notably, we also measure a comparatively high metallicity of log(O/H) + 12 = 8.83 ± 0.1 for the z = 0.296 host galaxy of GRB 050826. We also determine stellar masses (M⋆) for our LGRB host galaxy sample, finding a mean stellar mass of log(M⋆/M☉) = 9.25+0.19−0.23.
Multidimensional nonlinear geometric optics for transport operators with applications to stable shock formation

In $n \geq 1$ spatial dimensions, we study the Cauchy problem for a quasilinear transport equation coupled to a quasilinear symmetric hyperbolic subsystem of a rather general type. For an open set (relative to a suitable Sobolev topology) of regular initial data that are close to the data of a simple plane wave, we give a sharp, constructive proof of shock formation in which the transport variable remains bounded but its first-order Cartesian coordinate partial derivatives blow up in finite time. Moreover, we prove that the singularity does not propagate into the symmetric hyperbolic variables: they and their first-order Cartesian coordinate partial derivatives remain bounded, even though they interact with the transport variable all the way up to its singularity. The formation of the singularity is tied to the finite-time degeneration, relative to the Cartesian coordinates, of a system of geometric coordinates adapted to the characteristics of the transport operator. Two crucial features of the proof are that relative to the geometric coordinates, all solution variables remain smooth, and that the finite-time degeneration coincides with the intersection of the characteristics. Compared to prior shock formation results in more than one spatial dimension, in which the blowup occurred in solutions to wave equations, the main new features of the present work are: i) we develop a theory of nonlinear geometric optics for transport operators, which is compatible with the coupling and which allows us to implement a quasilinear geometric vectorfield method, even though the regularity properties of the corresponding eikonal function are less favorable compared to the wave equation case and ii) we allow for a full quasilinear coupling, i.e., the principal coefficients in all equations are allowed to depend on all solution variables.
Early and extensive alterations of glial connexins, distal oligodendrogliopathy type demyelination, and nodal/paranodal pathology are characteristic of multiple system atrophy

The pathological hallmark of multiple system atrophy (MSA) is aberrant accumulation of phosphorylated α‐synuclein in oligodendrocytes, forming glial cytoplasmic inclusions (GCIs). Extensive demyelination occurs particularly in the olivopontocerebellar and striatonigral pathways, but its precise mechanism remains elusive. Glial connexins (Cxs), which form gap junction channels between astrocytes and oligodendrocytes, play critical roles in myelin maintenance, and have not been studied in MSA. Therefore, we immunohistochemically investigated glial Cx changes in the cerebellar afferent fibers in 15 autopsied patients with MSA. We classified demyelinating lesions into three stages based on Klüver–Barrera staining: early (Stage I), intermediate (Stage II), and late (Stage III) stages showing subtle, moderate, and severe myelin reduction, respectively. Myelin‐associated glycoprotein, but not myelin oligodendrocyte glycoprotein, was preferentially decreased in Stage I, suggesting distal oligodendrogliopathy type demyelination. Accumulation of phosphorylated α‐synuclein in oligodendrocytes was frequently seen in Stage I but less frequently observed in Stages II and III. Tubulin polymerization‐promoting protein (TPPP/p25α)‐positive oligodendrocytes were preserved in Stage I but successively decreased in Stages II and III. Even at Stage I, Cx32 was nearly absent from myelin, despite the relative preservation of other nodal proteins, such as neurofascin, claudin‐11/oligodendrocyte‐specific protein, and contactin‐associated protein 1, which successively decreased in the later stages. Cx32 was re‐distributed in the oligodendrocyte cytoplasm and co‐localized with GCIs. Cx47 gradually decreased at the oligodendrocyte surface in a stage‐dependent manner but was not co‐localized with GCIs. Astrocytic Cx43 was down‐regulated in Stage I but up‐regulated in Stages II and III, reflecting astrogliosis. Cx43/Cx47 gap junctions significantly decreased from Stage I to III. Activated microglia/macrophages and T cells infiltrated in Stage I rather than Stages II and III. Therefore, early and extensive alterations of glial Cxs, particularly Cx32 loss, occur in MSA and may accelerate distal oligodendrogliopathy type demyelination and nodal/paranodal dysfunction through disruption of inter‐glial communication.
The clinical features of OSTM1‐associated malignant infantile osteopetrosis: A retrospective, single‐center experience over one decade

Mutation in OSTM1 give rise to the rarest and most lethal subtype of malignant infantile osteopetrosis (MIOP), and an improved understanding of OSTM1‐associated MIOP would help with informed decision‐making regarding symptom management and early palliative care referral. This retrospective study describes the clinical and laboratory features of patients with a genetic diagnosis of OSTM1 MIOP made between January 2011 and December 2021 in the Department of Pediatrics, Al‐Adan Hospital, Kuwait. Twenty‐two children had confirmed homozygous deletion in OSTM1 (13 females, nine males). Consanguinity was reported in almost all parents. 72.7% were diagnosed before the age of two months, most commonly incidentally with a high clinical suspicion. All 22 patients developed upper respiratory symptoms, hepatosplenomegaly, poor feeding, and had severe developmental delay. 80% of patients developed pain and/or irritability, and 40.9% were diagnosed with primary seizures. Bone fractures developed in 27% of patients, most likely iatrogenic, and some patients had hernia and gum abnormalities. The mean survival was 10.9 months. The clinical presentation, symptomatology, and mortality of our cohort were compared with other cases of OSTM1 MIOP identified through a comperhensive search of the PubMed database. The findings conclude that OSTM1 MIOP is a multi‐systemic disease with distinct clinical features, of which neurological complications are the most severe and include nociplastic pain and irritability. Although orthopedic complications influence the trajectory of most patients with other forms of osteopetrosis, OSTM1 MIOP is driven by its neurological complications. Hence, OSTM1 should be regarded as a neurodegenerative disease with osteopetrosis as a comorbidity that warrants early palliative care referral.
The role of bactericidal and opsonic activity in immunity against Bordetella pertussis

ABSTRACT Introduction Pertussis vaccines have drastically reduced the disease burden in humans since their implementation. Despite their success, pertussis remains an important global public health challenge. Bordetella pertussis resurgence could be a result of greater surveillance combined with improved diagnosis methods, changes in Bordetella pertussis biology, vaccine schedules, and/or coverage. Additionally, mechanisms of protection conferred by acellular pertussis (aP) and whole-cell pertussis (wP) vaccines differ qualitatively. There are no clear immune correlates of protection for pertussis vaccines. Pertussis antigens can induce toxin neutralizing antibodies, block adherence or engage complement mediated phagocytic/bactericidal killing. Areas covered We reviewed the existing evidence on antibody-mediated serum bactericidal and opsonophagocytic activity and discussed the relevance of these functional antibodies in the development of next-generation pertussis vaccines. Expert opinion Current paradigm proposes that wP vaccines may confer greater herd protection than aP vaccines due to their enhanced clearance of bacteria from the nasopharynx in animal models. Functional antibodies may contribute to the reduction of nasal colonization, which differentiates aP and wP vaccines. Understanding the intrinsic differences in protective immune responses elicited by each class of vaccines will help to identify biomarkers that can be used as immunological end points in clinical trials.
Examples of CM curves of genus two defined over the reflex field

Van Wamelen [Math. Comp. 68 (1999) no. 225, 307–320] lists 19 curves of genus two over $\mathbf{Q}$ with complex multiplication (CM). However, for each curve, the CM-field turns out to be cyclic Galois over $\mathbf{Q}$ , and the generic case of a non-Galois quartic CM-field did not feature in this list. The reason is that the field of definition in that case always contains the real quadratic subfield of the reflex field. We extend Van Wamelen’s list to include curves of genus two defined over this real quadratic field. Our list therefore contains the smallest ‘generic’ examples of CM curves of genus two. We explain our methods for obtaining this list, including a new height-reduction algorithm for arbitrary hyperelliptic curves over totally real number fields. Unlike Van Wamelen, we also give a proof of our list, which is made possible by our implementation of denominator bounds of Lauter and Viray for Igusa class polynomials.
Neural stochastic differential equations network as uncertainty quantification method for EEG source localization

EEG source localization remains a challenging problem given the uncertain conductivity values of the volume conductor models (VCMs). As uncertain conductivities vary across people, they may considerably impact the forward and inverse solutions of the EEG, leading to an increase in localization mistakes and misdiagnoses of brain disorders. Calibration of conductivity values using uncertainty quantification (UQ) techniques is a promising approach to reduce localization errors. The widely-known UQ methods involve Bayesian approaches, which utilize prior conductivity values to derive their posterior inference and estimate their optimal calibration. However, these approaches have two significant drawbacks: solving for posterior inference is intractable, and choosing inappropriate priors may lead to increased localization mistakes. This study used the Neural Stochastic Differential equations Network (SDE-Net), a combination of dynamical systems and deep learning techniques that utilizes the Wiener process to minimize conductivity uncertainties in the VCM and improve the inverse problem. Results revealed that SDE-Net generated a lower localization error rate in the inverse problem compared to Bayesian techniques. Future studies may employ new stochastic dynamical systems-based techniques as a UQ technique to address further uncertainties in the EEG Source Localization problem. Our code can be found here: https://github.com/rrwabina/SDENet-UQ-ESL.
Random matrix-valued multiplicative functions and linear recurrences in Hilbert-Schmidt norms of random matrices

We introduce the notion of a random matrix-valued multiplicative function, generalizing Rademacher random multiplicative functions to matrices. We provide an asymptotic for the second moment based on a linear recurrence property for Hilbert-Schmidt norms of sucessive products of random matrices. Moreover, we provide upper bounds for the higher even moments related to the generalized joint spectral radius.
Seroprevalence, co-infection and risk of transmission of Hepatitis B and D virus among hospital attendees in two South-western states in Nigeria

ABSTRACT Infection with both Hepatitis B (HBV) and D (HDV) virus causes more severe liver damage than HBV alone. Superinfections among chronic HBV infected cohorts often lead to HDV persistence with rapid progression to cirrhosis, necessitating continuous surveillance to determine their prevalence and relative contribution to liver pathology. A cross-sectional study among hospital outpatients in Ekiti and Osunstates was conducted using random sampling technique. Blood samples were collected from 410 participants and tested for HBV serological markers. All samples positive for HBsAg samples were tested for Hepatitis D virus antigen (HDAg), serum anti-HDV IgM, and serum anti-HDV IgG using enzyme-linked immunosorbent assay kits. The prevalence of HBV infection among the 410 samples was 12.4% (CI 9.5–15.9). Past HBV exposure was detected in 120 (29.2%), while 147(35.8%) were susceptible to HBV infection. Among the HBsAg positive individuals, 9.8% were hepatitis D antigen (HDAg) positive, while 3.9% and 1.9% were positive for IgG anti-HDV and IgM anti-HDV, respectively. Risk factors associated with HBV infections in this study were multiple sexual partners and sharing of sharp objects. Our investigation has verified the endemicity of HBV in Nigeria and revealed that HBV- HDV co-infection is highly prevalent in south-west Nigeria.
A note on the reciprocal theorem for the swimming of simple bodies

The use of the reciprocal theorem has been shown to be a powerful tool to obtain the swimming velocity of bodies at low Reynolds number. The use of this method for lower-dimensional swimmers, such as cylinders and sheets, is more problematic because of the undefined or ill-posed resistance problems that arise in the rigid-body translation of these shapes. Here, we show that this issue can be simply circumvented and give concise formulas obtained via the reciprocal theorem for the self-propelled motion of deforming two-dimensional bodies. We also discuss the connection between these formulae and Faxen’s laws.
The ATLAS3D project - X. On the origin of the molecular and ionized gas in early-type galaxies

We make use of interferometric CO and HI observations, and optical integral-field spectroscopy from the ATLAS 3D survey to probe the origin of the molecular and ionised interstellar medium (ISM) in local early-type galaxies. We find th at 36±5% of our sample of fast rotating early-type galaxies have their ionised gas kinematically misaligned with respect to the stars, setting a strong lower limit on the importance of e xternally acquired gas (e.g. from mergers and cold accretion). Slow rotators have a flat distri bution of misalignments, indicating that the dominant source of gas is external. The molecular, ionised and atomic gas in all the detected galaxies are always kinematically aligned, even when they are misaligned from the stars, suggesting that all these three phases of the interst ellar medium share a common origin. In addition, we find that the origin of the cold and warm ga s in fast-rotating early-type galaxies is strongly affected by environment, despite the molecular gas detection rate and mass fractions being fairly independent of group/cluster membership. Galaxies in dense groups and the Virgo cluster nearly always have their molecular gas kinematically aligned with the stellar kinematics, consistent with a purely internal origin (pres umably stellar mass loss). In the field, however, kinematic misalignments between the stellar and gaseous components indicate that at least 42±5% of local fast-rotating early-type galaxies have their ga s supplied from external sources. When one also considers evidence of accretion present in the galaxies’ atomic gas distributions, > 46% of fast-rotating field ETGs are likely to have acquired a d etectable amount of ISM from accretion and mergers. We discuss several scenarios which could explain the environmental dichotomy, including preprocessing in galaxy groups/cluster outskirts and the morphological transformation of spiral galaxies, but we find it difficult to simultaneously explain the kinematic misalignment difference and the constant detection rate. Furthermore, our results suggest that galaxy mass may be an important independent factor associated with the origin of the gas, with the most massive fast-rotating ga laxies in our sample (MK < 24 mag; stellar mass of �8×10 10 M⊙) always having kinematically aligned gas. This mass dependence appears to be independent of environment, suggesting it is caused by a separate physical mechanism.
Tunnel Splitting in Asymmetric Double Well Potentials: An Improved WKB Calculation

We present an improved Wentzel-Kramers-Brillouin (WKB) calculation of tunnel splitting in one dimensional asymmetric double well potentials. We show that the tunnel splitting in general can have linear dependence on the bias energy, beside the well-known quadratic dependence. We demonstrate that the linear correction is greater than previously thought.