Miracle-dz/UniFAR-FTUs huggingface dataset:
Time-dependent formation of the profile of the He 2 s 2 p P o 1 state excited by a short laser pulse

We produce quantitatively accurate data for the energy- and time-dependent formation of the profile of the differential ionization probability of the He $1{s}^{2}\phantom{\rule{0.2em}{0ex}}^{1}S$ ground state from the coherent excitation and decay of the doubly excited He $2s2p\phantom{\rule{0.2em}{0ex}}^{1}P^{o}$ resonance state induced by a pulse of duration of $450\phantom{\rule{0.3em}{0ex}}\mathrm{a.u. }$ and field strength in the range $F=0.4\ifmmode\times\else\texttimes\fi{}{10}^{\ensuremath{-}3}\phantom{\rule{0.3em}{0ex}}\mathrm{a.u. }\phantom{\rule{0.3em}{0ex}}\text{to}\phantom{\rule{0.3em}{0ex}}F=0.4\ifmmode\times\else\texttimes\fi{}{10}^{\ensuremath{-}1}\phantom{\rule{0.3em}{0ex}}\mathrm{a.u. }$ Two general methods were applied. One is analytic, using Fano's configuration interaction in the continuum in the framework of first order time-dependent perturbation theory. The other is numerical, using the state-specific expansion approach for the nonperturbative solution of the time-dependent Schr\"odinger equation. Electronic structures and electron correlation are incorporated via the use of state-specific wave functions for the initial state, the resonance state, and the continuum of scattering states. The results from the two methods are in perfect agreement, with a small discrepancy starting at $F=0.4\ifmmode\times\else\texttimes\fi{}{10}^{\ensuremath{-}1}\phantom{\rule{0.3em}{0ex}}\mathrm{a.u. }$ The weak field analytic formulas show explicitly the dependence of the profile formation on the pulse characteristics. In the limit of large times, the system becomes stationary and the computed resonance state profile yields the Fano asymmetry parameter of $q=\ensuremath{-}2.8$, with energy ${E}_{r}=60.20\phantom{\rule{0.3em}{0ex}}\mathrm{eV}$ and width $\ensuremath{\Gamma}=0.038\phantom{\rule{0.3em}{0ex}}\mathrm{eV}$. These values agree with previously published ones obtained from time-independent calculations and from photoabsorption measurements of the type initiated by Madden and Codling in 1963.
Adult-Generated Dentate Granule Cells in Epilepsy: Loyal Gatekeepers or Evil Changelings?

Adult Born Dentate Granule Cell Mediated Upregulation of Feedback Inhibition in a Mouse Model of Traumatic Brain Injury Kang YJ, Lee SH, Boychuk JA, Butler CR, Juras JA, Cloyd RA, Smith BN. J Neurosci. 2022;42(37):7077-7093. doi:10.1523/JNEUROSCI.2263-21.2022. PMID: 36002261; PMCID: PMC9480876. Post-traumatic epilepsy (PTE) and behavioral comorbidities frequently develop after traumatic brain injury (TBI). Aberrant neurogenesis of dentate granule cells (DGCs) after TBI may contribute to the synaptic reorganization that occurs in PTE, but how neurogenesis at different times relative to the injury contributes to feedback inhibition and recurrent excitation in the dentate gyrus is unknown. Thus, we examined whether DGCs born at different postnatal ages differentially participate in feedback inhibition and recurrent excitation in the dentate gyrus using the controlled cortical impact (CCI) model of TBI. Both sexes of transgenic mice expressing channelrhodopsin2 (ChR2) in postnatally born DGCs were used for optogenetic activation of three DGC cohorts: postnatally early born DGCs, or those born just before or after CCI. We performed whole-cell patch-clamp recordings from ChR2-negative, mature DGCs and parvalbumin-expressing basket cells (PVBCs) in hippocampal slices to determine whether optogenetic activation of postnatally born DGCs increases feedback inhibition and/or recurrent excitation in mice 8-10 weeks after CCI and whether PVBCs are targets of ChR2-positive DGCs. In the dentate gyrus ipsilateral to CCI, activation of ChR2-expressing DGCs born before CCI produced increased feedback inhibition in ChR2-negative DGCs and increased excitation in PVBCs compared with those from sham controls. This upregulated feedback inhibition was less prominent in DGCs born early in life or after CCI. Surprisingly, ChR2-positive DGC activation rarely evoked recurrent excitation in mature DGCs from any cohort. These results support that DGC birth date-related increased feedback inhibition in of DGCs may contribute to altered excitability after TBI. Significance Statement: Dentate granule cells (DGCs) control excitability of the dentate gyrus through synaptic interactions with inhibitory GABAergic interneurons. Persistent changes in DGC synaptic connectivity develop after traumatic brain injury, contributing to hyperexcitability in post-traumatic epilepsy (PTE). However, the impact of DGC neurogenesis on synaptic reorganization, especially on inhibitory circuits, after brain injury is not adequately described. Here, upregulation of feedback inhibition in mature DGCs from male and female mice was associated with increased excitation of parvalbumin-expressing basket cells by postnatally born DGCs, providing novel insights into underlying mechanisms of altered excitability after brain injury. A better understanding of these inhibitory circuit changes can help formulate hypotheses for development of novel, evidence-based treatments for post-traumatic epilepsy by targeting birth date-specific subsets of DGCs.
Pregnancy Outcomes of Infertile Patients Presenting to Our Assisted Reproductive Technology Center

OBJECTIVE: In this study, we aimed to evaluate whether the demographic and stimulation characteristics, treatment results, and pregnancy outcomes of infertile couples who applied to our assisted reproductive technology center vary according to the calendar year. STUDY DESIGN: The original files of 949 patients who underwent assisted reproductive technology treatment were analyzed between January 2012 and December 2017. Assisted reproductive technology cycles were classified according to year and also basal parameters and assisted reproductive technology outcomes were compared by year. RESULTS: Female age, infertility period, baseline follicle-stimulating hormone, luteinizing hormone, estradiol levels, duration of stimulation, total gonadotropin dose required, peak E2 level, and endometrial thickness on human chorionic gonadotropin administration day were statistically significant between the groups (p<0.05). While a statistically significant difference was observed in fertilization rate (p<0.05), the following were comparable between the groups (p>0.05): number of retrieved and MII oocytes, two pronuclei, day of transfer, embryo transfer technique, single vs. multiple embryo transfer, rates of the Grade-I embryo, biochemical and clinical pregnancy, live birth, ectopic pregnancy, and miscarriage. CONCLUSION: Infertile women of reproductive age benefit from assisted reproductive technology when trying to become pregnant. Factors that could adversely affect assisted reproductive technology, such as advanced age, have a negative impact on the treatment’s success. These repercussions should be taken into account by infertile couples who consider delaying pregnancy.
The Most Active Child Is Not Always the Fittest: Physical Activity and Fitness Are Weakly Correlated

The present cross-sectional study aimed to evaluate the impact of physical activity level (PA) on physical fitness by controlling for individual characteristics in Italian children. A total of 329 children (girls n = 155, 42.6%; from five primary schools, 17 classes) aged 8–10 filled out the Physical Activity Questionnaire for Older Children (PAQ-C) to assess their PA level and performed anthropometric measurements (body mass, height, and BMI) and physical tests for measuring sprint (20 m sprint), cardiorespiratory fitness (shuttle-run test), balance (single-leg stance), handgrip strength (handgrip), lower-limb power (standing long-jump), peak force (countermovement jump), and low-back flexibility (sit-and-reach) skills. Linear mixed-effects models were applied to determine the relationship between physical fitness and PAQ-C score controlling for individual characteristics (i.e., gender, age, BMI). Results reported significant relationships between PAQ-C scores and sit-and-reach, shuttle-run, long-jump, and sprint tests. All considered physical tests were correlated with gender, age, and BMI, except for sit-and-reach from BMI. The variance in age, gender, BMI, and PAQ-C score accounted altogether for 30.0% of the variance in handgrip, 23.0% in single-leg stance, 26% in sit-and-reach, 36% in shuttle-run, 31% in long-jump, 34% in sprint, and 31% in countermovement jump. Therefore, the relationship between PA and fitness is not absolute and depends on the test and children’s characteristics.
The Effect of Anticipatory Apology and Appreciation in Online Support-Seeking Messages on Support Provision in the U.S. and Korea

This experiment examined how online support-seeking messages containing anticipatory apology and/or appreciation influence support provision in the U.S. and Korea. The mediating role of regard for face was also assessed. A total of 983 participants (568 in the U.S. sample, 415 in the Korean sample) read and responded to support-seeking messages posted on an interactive online platform. Results showed that support-seeking messages with anticipatory apology and/or appreciation elicited higher quality (in terms of person-centeredness) supportive messages than support-seeking messages without anticipatory apology or appreciation. Participants’ perceptions of support-seeker's regard for face mediated the effect of anticipatory apology in support-seeking messages on level of person-centeredness in received support messages. This pattern of findings was observed in both the American and Korean samples.
Disparate Time-to-Treatment and Varied Incidence of Actionable Non-Small Cell Lung Cancer Molecular Alterations in British Columbia: A Historical Cohort Study

Background: non-small cell lung cancer (NSCLC) outcomes remain suboptimal for early-stage disease despite emerging advances in systemic therapy for the peri-operative period. Next-generation sequencing (NGS) identifies driver mutations for which targeted therapies have been developed that improve survival. The BC lung cancer screening program, which was initiated in May 2022, is expected to identify people with early and late stages of NSCLC. It is crucial to first understand the molecular epidemiology and patterns of time to initiate treatment across its five health authorities (HA) to optimize the delivery of care for NSCLC in BC. In this way, we may harness the benefits of targeted therapy for more people with NSCLC as novel advances in therapy continue to emerge. Objective: to compare (a) the frequency of actionable NSCLC molecular alterations among HAs and (b) the time to treatment initiation. Methods: a retrospective observational study was conducted with prospectively collected data from the BC CGL Database. Adults with late stage NSCLC who underwent targeted NGS were included for the time period from May 2020 to June 2021. Demographics, actionable molecular alterations, PDL-1 expression, and time to treatment across HAs were examined. Using appropriate statistical tests for comparison among HAs, p>0.05 was deemed significant. Results: 582 patients underwent NGS/IHC and analysis during the study period. The mean age was 71 (10.1), and 326 (56%) patients were female. A significantly higher proportion of all EGFRm+ were identified within Vancouver Coastal Health (VCHA) and Fraser Health Authority (FHA) compared to the other health authorities (p < 0.001). This also holds true for common sensitizing EGFRm+ alone (p < 0.001) and for sensitizing EGFRm+ when adjusted for females and smoker status (OR 0.75; 95% CI 0.62, 0.92; p = 0.005). Patients residing within the Northern, Interior, and Island HAs were less likely to receive treatment at the same rate as those in VCHA and FHA HAs. Conclusion: actionable NSCLC driver mutations are present in all regional HAs, with disparity noted in time to initiate treatment between HAs. This provides evidence for the importance of molecular testing for patients in all BC HAs to guide personalized and timely NSCLC treatment.
Low threshold and efficient multi-wavelength Brillouin-erbium fiber laser incorporating a fiber Bragg grating filter with intra-cavity pre-amplified Brillouin pump

A low threshold and efficient multi-wavelength Brillouin-erbium fiber laser with a pre-amplified Brillouin pump within a Fabry-Perot cavity is presented. With the utilization of a fiber Bragg grating filter as one of the fiber loop mirrors, up to 25 stable Brillouin Stokes lines could be generated with channel spacing of 0.088 nm. The architecture of the design consumes only 3 dBm of the Brillouin pump power and 90 mW of the 980 nm laser diode to produce the 25 maximum output channels. The signal to noise ratio of each channel was also observed to be not less than 20 dB.
INTERSTELLAR EXTINCTION IN THE DIRECTION OF THE OPEN CLUSTER M29

The interstellar extinction is investigated in a 1.5 deg2 area in the direction of the open cluster M29 (NGC 6913) in Cygnus, centered at R.A. = 20h 24m, decl. = +38° 30′. The study is based on photometric classification of 1110 stars in spectral and luminosity classes down to V = 19 mag using photometry in the Vilnius seven-color system published in (Milašius et al. ). Additionally, in the same area the extinction is investigated using 1147 red clump giants (RCGs), identified by combining selected two-color diagrams of the 2MASS and Spitzer surveys. The investigated area is divided into three parts with different obscuration and in these directions the extinction versus distance plots up to 5 kpc are presented. In the whole area a steep rise of the extinction is observed at a distance of ∼800 pc; it should be related to dust clouds in the Great Cygnus Rift obscuring the stars behind it by AV = 4.0–4.7 mag. RCGs exhibit much larger extinction values, up to A K s ? > = 1.2–1.3 mag in the more transparent areas and 1.45 mag in the northeastern part of the area and above it, where the dust cloud TGU H466 is located. These values of A K s ? > correspond to AV = 10–12 mag. We do not exclude the possibility that the largest values of the extinction belong not to RCGs but to some contaminating intrinsically red AGB stars penetrated through the applied RCG selection constraints. The extinction in the TGU H466 cloud probably originates in two cloud systems—the Great Cygnus Rift at 800 pc and the Cygnus X complex of dust and molecular clouds at 1.3–1.5 kpc.
Molecular beam epitaxy growth and scanning tunneling microscopy study of 2D layered materials on epitaxial graphene/silicon carbide

Since the advent of atomically flat graphene, two-dimensional (2D) layered materials have gained extensive interest due to their unique properties. The 2D layered materials prepared on epitaxial graphene/silicon carbide (EG/SiC) surface by molecular beam epitaxy (MBE) have high quality, which can be directly applied without further transfer to other substrates. Scanning tunneling microscopy and spectroscopy (STM/STS) with high spatial resolution and high-energy resolution are often used to study the morphologies and electronic structures of 2D layered materials. In this review, recent progress in the preparation of various 2D layered materials that are either monoelemental or transition metal dichalcogenides on EG/SiC surface by MBE and their STM/STS investigations are introduced.
Efficiency of Multiple Ovulation and Embryo Transfer (MOET) in a Cattle Farm over a Period of Ten Years in Gujarat

The present study was conducted at Sabarmati Ashram Gaushala, Bidaj, Gujarat. A total of 427 donor animals were investigated over a ten-year period to assess the efficiency of Standard protocol of Multiple Ovulation and Embryo Transfer (MOET). Simultaneously a season wise and breed wise study was also conducted. Breeds studied were Gir, HF, HFCB, Jersey, JYCB, Red Sindhi and Sahiwal. Overall average number of embryos, average number of viable embryos, number of pregnancies and conception rate (%) were found to be 7.8, 4.8, 281 and 39.4, respectively. The year-wise number of pregnancies and conception rates varied from 09 to 42, and 24.6% in 2009-10 to the highest 61.3% in 20014-15, respectively. Further, breed-wise results showed average viable embryo in different breeds as 2.8 in Gir, 4.1 in HF, 5.1 in HFCB, 6.3 in Jersey, 5.8 in JYCB, 3.7 in Red Sindhi and 6.6 in Sahiwal, with corresponding conception rates of 67.7. 34.6, 28.8, 53.1, 39.4, 47.1 and 36.4 %, respectively. A trend was observed that the efficiency of MOET programme was less during monsoon (31.2%) as compared to summer and winter (41.5 and 41.4%).
Instagram Influencers Credibility Dimensions and Purchase Intention of Followers: Empirical Evidence

The advent of SMIs has primarily altered the means business connect with their prospects and customers. Currently, many SNSs enables SMIs to endorse the products, share opinions, provide feedback, and communicate with their followers either publicly or privately. This research aims to determine the mediating effect of loyalty of followers towards the influencer and ascribed opinion leadership on SMIs dimensions (expertise, trustworthiness, and attractiveness) and purchase intention relationship from the perspective of Instagram users in India. To measure the objective, the study acquired responses from 250 Indian Instagram users in the age group of 18-24. Results indicated that the purchase intention of followers is positively influenced by expertise, trustworthiness, ascribed opinion leadership, and loyalty of followers towards the influencer dimensions. Here, ascribed opinion leadership and loyalty of followers towards the influencer acts as an effective arbitrator between SMIs dimensions (expertise, trustworthiness, and attractiveness) and purchase intention relationship. The study suggests that before engaging SMI to promote the brand, the companies should understand the perception of followers towards the influencer in terms of expertise, attractiveness, and trustworthiness dimensions.
Decreasing the Displacement Rank of a Matrix

This paper approximates a matrix B having a displacement rank r by a matrix $B_d $ having a lower displacement rank d (for a fixed $d < r $), so as to minimize the approximation error norm. $\| B_d - C \|_2 $ for any matrix C in terms of $\| B - C \|_2 $ is estimated.
Spatial Variability of Sea Level Pressure and 500 mb Height Anomalies over the Southern Hemisphere

Abstract The spatial variability of mean sea level pressure (SLP) and 500 mb height anomalies over the Southern Hemisphere during summer (DJF) and winter (JJA) is determined using eigenvector analysis based on daily synoptic maps from 1972 to 1979. The patterns of spatial distribution of pressure and height anomalies are further verified and examined by means of station data, and the eigenvectors are compared between the seasons and to those found for the Northern Hemisphere. The first eigenvector shows that midlatitude anomalies of SLP and 500 mb height are of an opposite sign to those found over and around Antarctica. The pattern is highly barotropic and suggests strengthening and weakening of the zonal wind in alternating latitude belts. The 500 mb height differences are calculated for five midlatitude to Antarctic station pairs using data from the late 1950's onward. These latitudinal height differences are also used to describe the association between the hemispheric westerlies and the Southern Oscil.
Relationship between Stock Return, Trading Volume, and Trading Price of Agriculture Development Bank

The main objective of the study is to measure the causal relationship between stock return, trading volume, and the trading price of Agriculture Development bank. Descriptive research and casual comparative research designs have been used to analyze the study. The 11years panel data has been used. The 2104 observations are analyzed to draw a valid conclusion about the study. The descriptive model provides evidence of average stock return, trading volume, and price volatility. The investors of ADB faced high risk in stock investment during the 11 years. There is a significant positive relationship between them. Similarly, there is a positive and significant impact of trading volume and trading price on stock return.
Molecular Analysis of Genetic Diversity and Structure of the Lablab (Lablab purpureus (L.) Sweet) Gene Pool Reveals Two Independent Routes of Domestication

In this study, genetic diversity and structure of 474 cultivated and 19 wild lablab (Lablab purpureus) accessions. were determined using 15 nuclear and 6 chloroplast SSR markers. The overall gene diversity was relatively low (0.3441). Gene diversity in the wild accessions (0.6059) was about two-folds greater than that in the cultivated accessions. In the wild accessions, gene diversity was greatest in the southern Africa, followed by East Africa. In the cultivated accessions, gene diversity was highest in the eastern Africa. The results suggested that South Africa is the center of origin and East Africa is the center of domestication of lablab. Different cluster analyses showed that 2-seeded-pod cultivated accessions (ssp. uncinatus) were clustered with wild accessions and that 4–(6)-seeded-pod cultivated accessions (ssp. purpureus and bengalensis) were intermingled. UPGMA tree suggested that ssp. purpureus and bengalensis were domesticated from 4-seeded-pod wild accessions of southern Africa. Haplotype network analysis based on nuclear SSRs revealed two domestication routes; the ssp. uncinatus is domesticated from 2-seeded-pod wild lablab (wild spp. uncinatus) from East Africa (Ethiopia), while the ssp. purpureus and bengalensis are domesticated from 4-seeded-pod wild lablab from Central Africa (Rwanda). These results are useful for understanding domestication and revising classification of lablab.
Energy and Throughput Management in Delay-Constrained Small-World UAV-IoT Network

Multihop data routing over a large-scale Internet of Things (IoT) network results in energy imbalance and poor data throughput performance. In addition, data transmission using a large number of hops causes more delay. In light of this, in this work, a novel method of energy and throughput management in a delay-constrained small-world unmanned aerial vehicle (UAV)-IoT network is proposed. The proposed small-world framework optimizes the number of hops required for the data transmission leading to improved energy efficiency and quality of service. The method introduces optimal long-range links between device pairs resulting in low average path length and high clustering coefficient which are called as small-world characteristics. Therefore, in this work, UAVs are deployed to collect the data from IoT devices and forward it to the ground station (GS) utilizing the small world framework. It is shown through results that the network delays corresponding to the proposed method, conventional routing method, low-energy adaptive clustering hierarchy (LEACH) protocol, modified LEACH protocol, and canonical particle multiswarm (CPMS) method are 789.39, 1602.53, 1000.92, 873.63, and 999.79 s, respectively. It is also observed that the number of dead UAVs in case of the proposed method is reduced when compared to other existing methods. It is also noticed that the proposed method results in 100% packet delivery ratio (PDR) dominating LEACH and modified LEACH protocols. Thus, it is shown that the proposed method outperforms the other shortest path methods in terms of network latency, lifetime, and PDR. Further, the effect of location of GS, velocities of UAVs, and hovering heights of UAVs is considered for the performance evaluation of the proposed method. The obtained results validate the significance of utilization of the proposed method over various network scenarios.