Miracle-dz/UniFAR-FTUs huggingface dataset:
A characterization of cancellation ideals

An ideal I of a commutative ring R with identity is called a cancellation ideal if whenever IB = IC for ideals B and C of R, then B = C. We show that an ideal I is a cancellation ideal if and only if I is locally a regular principal ideal. Let R be a commutative ring with identity. An ideal I of R is called a cancellation ideal if whenever IB = IC for ideals B and C of R, then B = C. It is easily seen that I is a cancellation ideal if and only if whenever IB ⊆ IC for ideals B and C of R, then B ⊆ C. A good introduction to cancellation ideals may be found in Gilmer [1, Section 6]. As for examples, it is easy to see that a principal ideal (a) is a cancellation ideal if and only if (a) is a regular ideal (i.e., a is not a zero divisor). An invertible ideal is a cancellation ideal. More generally, an ideal that is locally a regular principal ideal is a cancellation ideal. The purpose of this paper is to prove the converse. Kaplansky [2, Theorem 287] proved that a finitely generated cancellation ideal in a quasi-local domain is principal. We begin with the following lemma which is a modification of Kaplansky’s result (see [1, Exercise 7, page 67]). We use essentially the same argument. Lemma. Let R be a commutative ring with identity and let I be a cancellation ideal of R. Suppose that I = (x, y)+A where A is an ideal of R containing MI for some maximal ideal M . Then I = (x) +A or I = (y) +A. Proof. Put J = ( x + y, xy, xA, yA,A ) . Then it is easily checked that IJ = I. Since I is a cancellation ideal, we have J = I. Thus x = λ ( x + y ) + terms from ( xy, xA, yA,A ) . First, suppose that λ ∈ M . Since λx ∈ MI ⊆ A, we have x ∈ (y2, xy, xA, yA,A2). LetK = (y)+A. Then I = IK. Since I is a cancellation ideal, we have I = K. Next, suppose that λ / ∈M . Then for some μ ∈ R andm ∈M , we have μ (−λ) = 1+m. Now −μλy2 = μ (λ− 1)x+ terms from (xy, xA, yA,A2). Since my = (my) y ∈ (MI) y ⊆ Ay, we have y ∈ (x2, xy, xA, yA,A2). Thus, as in the first case, we get that I = (x) +A. Theorem. Let R be a commutative ring with identity. An ideal I of R is a cancellation ideal if and only if I is locally a regular principal ideal. Received by the editors May 16, 1996. 1991 Mathematics Subject Classification. Primary 13A15.
T-type Ca2+ channels play a dual role in modulating the excitability of dorsal root ganglia neurons

A subgroup of low-threshold dorsal root ganglia (DRG) neurons discharge action potentials (APs) with an afterdepolarizing potential (ADP). The ADP is formed by T-type Ca2+ currents. It is known that T-type Ca2+ currents contribute to neuropathic pain. However, the change in ADP-firing of injured DRG neurons has not been widely studied yet. Here we applied patch clamp to record ADP-firing and T-type Ca2+ currents in intact and chronically compressed DRG (CCD) neurons and examined T-type Ca2+ channel proteins expression with western blotting. After CCD injury, the incidences of both ADP firing and non-ADP burst firing increased, and T-type Ca2+ channels contributed to both of these firing patterns. The neurons discharging large-amplitude-ADP firing were TTX-insensitive, implying that high-density T-type Ca2+ channels might cooperate with TTX-insensitive Na+ channels to reduce the AP threshold. By contrast, the neurons displaying non-ADP burst firing were TTX-sensitive, implying that low density T-type Ca2+ channels may cooperate with TTX-sensitive Na+ channels to increase AP number. In DRG neurons, T-type Ca2+ currents density varied widely, ranging between 100 pA/pF and 5 pA/pF. After injury, the proportion of DRG neurons with large T-type Ca2+ currents increased in parallel with the increase in the incidence of large-amplitude-ADP firing. And in addition to Cav3.2, Cav3.3 channels are also likely to contribute to low-threshold firing. The data revealed that T-type Ca2+ channels may play a dual role in modulating the injured neurons’ high excitability through a cooperative process with Na+ channels, thereby contributing to neuropathic pain.
Romiplostim use in pregnant women with immune thrombocytopenia

Treatment for immune thrombocytopenia (ITP) in pregnancy is hampered by the lack of fetal safety evidence of maternally‐administered medications. The Pregnancy Surveillance Program (PSP) collected patient information from 2017–2020 for pregnancy, birth outcomes, and adverse events (AEs) for 186 women exposed to romiplostim from 20 days before pregnancy to the end of pregnancy. Timing of exposure was available in 128 women. Seventy‐one mothers (38%) had prepregnancy exposure to romiplostim; intrapartum exposure was known for the first (for many mothers when they discovered their pregnancy), second, and third trimesters for 74 (40%), 22 (12%), and 44 (24%) mothers, respectively, with 15 mothers exposed during >1 trimester. Among the 86 mothers with known pregnancy outcomes, 46 (53%) had at least one pregnancy‐related serious AE (SAE); approximately 2/3 of SAEs were due to underlying ITP. Of 92 mothers with known birth outcomes, 60 (65%) had a normal pregnancy and 16 (17%) had complications, with both categories including term and preterm births; there were 12 (14%) spontaneous miscarriages/stillbirths, 3 (3%) ectopic pregnancies, and 1 (1%) molar pregnancy. Most abnormal births resulted from abnormal pregnancies. There were five neonatal/postnatal AEs of note: inguinal hernia, cytomegalovirus infection, trisomy 8 (third trimester single‐dose romiplostim exposure), single umbilical artery without known anomalies, and development of autism at age 2 years. Seven of 12 infants with neonatal thrombocytopenia had resolution of thrombocytopenia before discharge; all 12 were discharged. Review of pregnancies in women exposed to romiplostim did not reveal any specific safety concerns for mothers, fetuses, or infants.
An LMI approach to h_ index and mixed h_ /h∞ fault detection observer design

Using the newly developed worst-case fault sensitivity measure, the H_ index, and the well-known worst-case robustness measure, the H ∞ norm, this paper addresses the problem of H_ index fault detection observer design and multiobjective H_/H ∞ fault detection observer design problems. Necessary and sufficient conditions for the existence of such a fault detection observer are given in terms of matrix inequalities. Both infinite frequency range case [0, ∞) and finite frequency range case [0, ω) are considered. Iterative linear matrix inequality (ILMI) algorithms are given to obtain the solutions. The effectiveness of the proposed approaches is shown by numerical examples.
Harnessing the Power of Technology to Improve Sexual and Reproductive Youth Health in Nicaragua: A Randomized Field Study

Introduction: Nicaragua is among the poorest countries in Latin America and has one of the highest adolescent pregnancy rates in the region. One in four of pregnancies are adolescents and they are more likely to experience poverty and gender and economic inequality. Method: This pilot randomized field study assessed use, satisfaction, and impact of a brief e-learning short-term intervention to improve the sexual and reproductive health (SRH) knowledge, skills, motivations, and behaviors among 14–17-year-old Nicaraguan youth. Results: While access to technology and internet were significant barriers, App and email delivery channels were feasible means for communicating with youth who had access to the internet and mobile devices. Youth who used the app were most likely to complete the entire intervention. Youth were very satisfied with the intervention (98%) and significantly improved SRH knowledge, skills and motivations, and delayed age at the first sexual encounter. Conclusion: Results are promising and indicate potential for the scalability of this type of intervention.
HIV-related stigma among healthcare providers working within infectious diseases and gynecology and obstetrics at a large teaching hospital in Denmark

ABSTRACT HIV-related stigma experienced in healthcare settings may be particularly detrimental to people with HIV (PWH). This study aims to examine the drivers of stigma and enacted HIV-related stigma among healthcare providers working in HIV and non-HIV care at a large teaching hospital in Denmark. In total, 162 providers working in gynecology and obstetrics, and 57 providers working in infectious diseases completed the “Measuring HIV stigma and discrimination among health facility staff” questionnaire. Compared to providers working in infectious diseases, providers working in gynecology and obstetrics had less training in infection control, HIV, and stigma, and although their level of worry and negative attitudes toward PWH was overall low, they were more like to use extra precaution measures (e.g., double gloves) when caring for PWH (20% versus 0%). Addressing HIV-related stigma in healthcare is important, as any amount of HIV-related stigma from providers has the potential to compromise the patients’ engagement in care and health outcomes.
Archaeological adhesives made from Podocarpus document innovative potential in the African Middle Stone Age

Significance This study addresses the earliest adhesives made in the African Middle Stone Age. We found a previously unknown way to produce an adhesive from Podocarpus conifer trees. Instead of collecting adhesive substances in nature, people produced tar by distillation. We identify two pathways for making tar, an above-ground method that is “discoverable” and a more laborious underground process requiring imagination and skill. The results have implications for our interpretation of early fire-based technology in Africa. Podocarpus tar production is an excellent proxy for recognizing complex cognition in Middle Stone Age archaeological records.
Segregation, integration and balance in resting‐state brain functional networks associated with bipolar disorder symptoms

Bipolar disorder (BD) is a serious mental disorder involving widespread abnormal interactions between brain regions, and it is believed to be associated with imbalanced functions in the brain. However, how this brain imbalance underlies distinct BD symptoms remains poorly understood. Here, we used a nested‐spectral partition (NSP) method to study the segregation, integration, and balance in resting‐state brain functional networks in BD patients and healthy controls (HCs). We first confirmed that there was a high deviation in the brain functional network toward more segregation in BD patients than in HCs and that the limbic system had the largest alteration. Second, we demonstrated a network balance of segregation and integration that corresponded to lower anxiety in BD patients but was not related to other symptoms. Subsequently, based on a machine‐learning approach, we identified different system‐level mechanisms underlying distinct BD symptoms and found that the features related to the brain network balance could predict BD symptoms better than graph theory analyses. Finally, we studied attention‐deficit/hyperactivity disorder (ADHD) symptoms in BD patients and identified specific patterns that distinctly predicted ADHD and BD scores, as well as their shared common domains. Our findings supported an association of brain imbalance with anxiety symptom in BD patients and provided a potential network signature for diagnosing BD. These results contribute to further understanding the neuropathology of BD and to screening ADHD in BD patients.
Lead toxicity due to retained intracranial bullet fragments: illustrative case

BACKGROUND Lead toxicity (plumbism) secondary to retained lead bullet fragments is a rare complication in patients with gunshot wounds. To the authors’ knowledge, there has been no definitive case reported of lead toxicity due to retained intracranial bullet fragments. OBSERVATIONS The authors reported the case of a 23-year-old man who presented after being found down. Computed tomography scanning of the head revealed bullet fragments within the calvaria adjacent to the left transverse sinus. During follow-up, he developed symptoms of plumbism with paresthesias in his bilateral hands and thighs, abdominal cramping, labile mood, and intermittent psychosis. Plumbism was confirmed with sequentially elevated blood lead levels (BLLs). The patient opted for surgical removal of the bullet fragments, which led to reduction in BLLs and resolution of his symptoms. LESSONS Although rare, lead toxicity from retained intracranial bullet fragments should be considered in patients who have suffered a gunshot wound to the head and have symptoms of lead toxicity with elevated BLLs. For safe and accessible intracranial bullet fragments in patients with plumbism, surgical intervention may be indicated.
VIRIAL INFECTIONS: REPLICATION AND PATHOGENESIS MECHANISMS TO THERAPY Enhancement of the Bactericidal Effect of Antibiotics by Inhibition of Enzymes Involved in Production of Hydrogen Sulfide in Bacteria

Counteraction of the origin and distribution of multidrug-resistant pathogens responsible for intra-hospital infections is a worldwide issue in medicine. In this brief review, we discuss the results of our recent investigations, which argue that many antibiotics, along with inactivation of their traditional biochemical targets, can induce oxidative stress (ROS production), thus resulting in increased bactericidal efficiency. As we previously showed, hydrogen sulfide, which is produced in the cells of different pathogens protects them not only against oxidative stress but also against bactericidal antibiotics. Next, we clarified the interplay of oxidative stress, cysteine metabolism, and hydrogen sulfide production. Finally, demonstrated that small molecules, which inhibit a bacterial enzyme involved in hydrogen sulfide production, potentiate bactericidal antibiotics including quinolones, beta-lactams, and aminoglycosides against bacterial pathogens in in vitro and in mouse models of infection. These inhibitors also suppress bacterial tolerance to antibiotics by disrupting the biofilm formation and substantially reducing the number of persister bacteria, which survive the antibiotic treatment. We hypothesise that agents which limit hydrogen sulfide biosynthesis are effective tools to counteract the origin and distribution of multidrug-resistant pathogens.
Objective excyclotorsion increases with aging in adults

ABSTRACT Introduction It has been reported that the disc-fovea angle (DFA), a measure of objective cyclotorsion, increases with age. DFA was measured in three age groups of adults and the effects of age, sex, and laterality on DFA is reported. Methods and Subjects A retrospective study was performed on patients who had a glaucoma checkup or who visited for suspected cataract, who underwent fundus photography between 2013 and 2021. Patients with visual acuity <0.7, axial length >27 mm, strabismus or ocular diseases affecting fusion were excluded. DFA was measured from digital fundus photographs obtained from 249 participants comprising three age groups (group I, 44.4 ± 0.5 years, n = 58; group II, 63.7 ± 3.6 years, n = 129; group III, 81.0 ± 3.8 years, n = 62). The sum of right- and left-eye DFAs is named as total DFA. Results Dunnett’s post-hoc test after ANOVA showed that the left-eye DFA and total DFA of group III were significantly larger than those of group I (p = .01 and p < .01, respectively). Total DFA of female participant (15.6 ± 4.7°, n = 168) was significantly larger than that of male participant (13.9 ± 4.3°, n = 81) (p < .01). The DFA of the left eye (8.2 ± 3.5°, n = 249) was significantly larger than that of the right eye (6.8 ± 3.3°, n = 249) (p < .001). Group III was subdivided based on eye dominance (right eye dominance, n = 36; left eye dominance, n = 13; NA, n = 13). The DFA in the nondominant eye (9.7 ± 4.6°) was significantly larger than that in the dominant eye (7.4 ± 3.7°) (p < .01). Discussion This study found a slight increase of DFA with age. Furthermore, DFA in female or DFA in the left-eye was larger than DFA in male or in the right-eye.
HEATING OF THE MAGNETIZED SOLAR CHROMOSPHERE BY PARTIAL IONIZATION EFFECTS

In this paper, we study the heating of the magnetized solar chromosphere induced by the large fraction of neutral atoms present in this layer. The presence of neutrals, together with the decrease with height of the collisional coupling, leads to deviations from the classical magnetohydrodynamic behavior of the chromospheric plasma. A relative net motion appears between the neutral and ionized components, usually referred to as ambipolar diffusion. The dissipation of currents in the chromosphere is enhanced by orders of magnitude due to the action of ambipolar diffusion, as compared with the standard ohmic diffusion. We propose that a significant amount of magnetic energy can be released to the chromosphere just by existing force-free 10–40 G magnetic fields there. As a consequence, we conclude that ambipolar diffusion is an important process that should be included in chromospheric heating models, as it has the potential to rapidly heat the chromosphere. We perform analytical estimations and numerical simulations to prove this idea.
Brain dynamics of recommendation-based social influence on preference change: A magnetoencephalography study

ABSTRACT People change their preferences when exposed to others’ opinions. We examine the neural basis of how peer feedback influences an individual’s recommendation behavior. In addition, we investigate if the personality trait of ‘agreeableness’ modulates behavioral change and neural responses. In our experiment, participants with low and high agreeableness indicated their degree of recommendation of commercial brands, while subjected to peer group feedback. The associated neural responses were recorded with concurrent magnetoencephalography. After a delay, the participants were asked to reevaluate the brands. Recommendations changed consistently with conflicting feedback only when peer recommendation was lower than the initial recommendation. On the neural level, feedback evoked neural responses in the medial frontal and lateral parietal cortices, which were stronger for conflicting peer opinions. Conflict also increased neural oscillations in 4–10 Hz and decreased oscillations in 13–30 Hz in medial frontal and parietal cortices§. The change in recommendation behavior was not different between the low and high agreeableness groups. However, the groups differed in neural oscillations in the alpha and beta bands, when recommendation matched with feedback. In addition to corroborating earlier findings on the role of conflict monitoring in feedback processing, our results suggest that agreeableness modulates neural processing of peer feedback.
Optimization of cobalt, nickel, and iron supplement for mesophilic and thermophilic anaerobic digestion treating high-solid food waste

ABSTRACT The effects of trace metals (iron (Fe), cobalt (Co) + Fe, and Co + nickel (Ni) + Fe) on mesophilic and thermophilic anaerobic digestion of food waste were quantified experimentally. Supplementation with 0 ≤ [Co] ≤ 5 mg/L, 0 ≤ [Ni] ≤ 10 mg/L, or 0 ≤ [Fe] ≤ 200 mg/L can significantly improve the productivity of mesophilic (MD) and thermophilic (TD) digesters. Addition of micronutrients increased biogas production, but excessive addition of trace metals hindered the production. Supplementation with Fe + Co or Fe + Co + Ni increased biogas production more than the addition of only Fe did. Within the design boundaries, the optimal concentrations for supplementation with three trace metals in MD were [Co] = 0.33 mg/L, [Ni] = 0.43 mg/L, and [Fe] = 5.35 mg/L, and in TD were [Co] = 1.41 mg/L, [Ni] = 3.84 mg/L, and [Fe] = 200 mg/L. TD required larger amounts of the trace metals than MD (4.3–37.4 times). The results can give quantitative information on trace metal supplementation for successful anaerobic digestion. GRAPHICAL ABSTRACT
Korean Guidelines for Postpolypectomy Colonoscopic Surveillance: 2022 revised edition

Colonoscopic polypectomy is effective in decreasing the incidence and mortality of colorectal cancer (CRC). Premalignant polyps discovered during colonoscopy are associated with the risk of metachronous advanced neoplasia. Postpolypectomy surveillance is the most important method for managing advanced metachronous neoplasia. A more efficient and evidence-based guideline for postpolypectomy surveillance is required because of the limited medical resources and concerns regarding colonoscopy complications. In these consensus guidelines, an analytic approach was used to address all reliable evidence to interpret the predictors of CRC or advanced neoplasia during surveillance colonoscopy. The key recommendations state that the high-risk findings for metachronous CRC following polypectomy are as follows: adenoma ≥10 mm in size; 3 to 5 (or more) adenomas; tubulovillous or villous adenoma; adenoma containing high-grade dysplasia; traditional serrated adenoma; sessile serrated lesion containing any grade of dysplasia; serrated polyp of at least 10 mm in size; and 3 to 5 (or more) sessile serrated lesions. More studies are needed to fully comprehend the patients who are most likely to benefit from surveillance colonoscopy and the ideal surveillance interval to prevent metachronous CRC.
Depth Restoration in Under-Display Time-of-Flight Imaging

Under-display imaging has recently received considerable attention in both academia and industry. As a variation of this technique, under-display ToF (UD-ToF) cameras enable depth sensing for full-screen devices. However, it also brings problems of image blurring, signal-to-noise ratio and ranging accuracy reduction. To address these issues, we propose a cascaded deep network to improve the quality of UD-ToF depth maps. The network comprises two subnets, with the first using a complex-valued network in raw domain to perform denoising, deblurring and raw measurements enhancement jointly, while the second refining depth maps in depth domain based on the proposed multi-scale depth enhancement block (MSDEB). To enable training, we establish a data acquisition device and construct a real UD-ToF dataset by collecting real paired ToF raw data. Besides, we also build a large-scale synthetic UD-ToF dataset through noise analysis. The quantitative and qualitative evaluation results on public datasets and ours demonstrate that the presented network outperforms state-of-the-art algorithms and can further promote full-screen devices in practical applications.
Compassion Fatigue and Spiritual Leaders: A Pilot Study

This is a pilot study on compassion fatigue experienced by spiritual leaders. The sample consisted of 15 religious affiliations with a total of 41 participants (30 males and 11 females). In this sample, spiritual leaders were not experiencing significant levels of compassion fatigue, and they were satisfied with their work. There was a significant negative correlation between satisfaction and exhaustion, r = −. 62, n = 35, p < . 01. Additionally, participants reported their coping strategies and support systems.