Miracle-dz/UniFAR-FTUs huggingface dataset:
Green Pit Viper Envenomations in Bangkok: A Comparison of Follow-Up Compliance and Clinical Outcomes in Older and Younger Adults

We compared older and younger adults envenomated by the green pit viper (GPV) with regard to the following: follow-up compliance, elapsed time between envenomation and emergency department (ED) visit, and clinical/treatment outcomes. This was a two-site retrospective cohort study. We searched hospital electronic medical databases between January 2011 and December 2021. Patients aged 15 and above were eligible if they had a history of snakebite and had at least two VCT and/or platelet count results in their medical records. After the search, 1550 medical records were reviewed and 760 cases were found to be eligible for analysis. In total, 205 cases (27.0%) were ≥60 years old. The median ages in the younger and older groups were 40 (26–51) and 68 (64–75) years, respectively. The median elapsed times from bite to the ED were 47 (30–118) vs. 69 (35–150) min (p-value = 0.001). Overall, 91.3% of all cases were managed as out-patient cases and were eligible for follow-up appointments. The rate of out-patient follow-up at 72 ± 12 h in the older patients was significantly higher (43.2%) than in the younger adult patients (32.4%) (p-value = 0.01). Regarding the clinical/treatment outcomes, the rates of coagulopathy, antivenom administration, and hospital admission were not statistically different between both groups.
Association of Elevated Serum Uric Acid with Nerve Conduction Function and Peripheral Neuropathy Stratified by Gender and Age in Type 2 Diabetes Patients

Background: The relationship between serum uric acid (SUA) level and diabetic peripheral neuropathy (DPN) remains controversial. We aimed to investigate the association between SUA level and DPN and evaluate the effects of SUA level on nerve conduction function via electromyography in patients with type 2 diabetes (T2DM), stratified by gender and age. Methods: This cross-sectional study included 647 inpatients with T2DM from the First Affiliated Hospital of Wenzhou Medical University between February 2017 and October 2020. The diagnosis of DPN was confirmed according to the Toronto Expert Consensus. Clinical data, SUA level, and nerve conduction parameters were obtained from electronic medical records. Results: A total of 647 patients with T2DM were included, and 471 patients were diagnosed with DPN. The level of SUA was higher in the DPN group than in the Non-DPN group (330.58 ± 99.67 vs. 309.16 ± 87.04, p < 0.05). After adjustment, a higher SUA level was associated with the presence of DPN [odds ratio (OR) 1.003, 95% confidence interval (CI), 1.001–1.005; p = 0.017]. The area under the curve for the prediction of DPN was 0.558 (95% CI, 0.509–0.608; p = 0.022), and the optimized cut-off of SUA level was 297.5 µmol/L. The SUA > 297.5 µmol/L level was independently associated with DPN in the male subgroup (OR 2.507, 95% CI, 1.405–4.473; p = 0.002) rather than in the female subgroup. Besides, SUA > 297.5 µmol/L was independently associated with DPN in the younger subgroup (age < 65 years) (OR 2.070, 95% CI, 1.278–3.352; p = 0.003) rather than in the older subgroup. In multiple linear regression analysis, SUA was significantly correlated with certain nerve conduction study parameters in the all patients group, and was also observed in the male and younger subgroups. Conclusions: Elevated SUA was independently associated with poorer nerve conduction functions, and hyperuricemia was also significantly associated with a higher risk of developing DPN in T2DM patients, especially in male and younger patients.
Forbidden Transitions in the Ground-State Configuration of Low-Z Phosphorus-like Ions

Systematically enlarged multiconfiguration Dirac-Fock wave functions have been applied in order to investigate the forbidden lines among the 3s23p3 ground-state levels for phosphorus-like ions at the neutral end of the sequence. The probabilities and ratios of these lines are important in the diagnostics of astrophysical plasmas. In a recent computation by Keenan et al., these probabilities were found to differ by up to ~25% from earlier (partially semiempirical) computations. To analyze this discrepancy in the context of ab initio structure theory, we report on a series of large-scale computations for these magnetic dipole and electric quadrupole transition probabilities. Our computations do not confirm the deviations found by Keenan et al. Detailed comparisons are made with previous calculations and observed data on the separation of energy levels and transition probabilities for the four ions P I, S II, Cl III, and Ar IV. Our study clearly demonstrates the possibility of a systematic approach, but also shows the effort that is needed to obtain sufficiently accurate atomic data for systems with five (or more) valence electrons.
On the seeding of equatorial spread F by gravity waves

The Naval Research Laboratory three‐dimensional simulation code SAMI3/ESF is used to study the response of the postsunset ionosphere to plane gravity waves. The effect of the vertical wind component of the wave is included as well as the effect of the background vertical wind, which can suppress equatorial spread F (ESF). It is shown that the strength of the coupling of the gravity wave to ESF increases with the vertical wavelength of the gravity wave. Long vertical wavelength modes (λ > 100 km) are more effective for seeding ESF.
Never Merely as a Means: Rethinking the Role and Relevance of Consent

Abstract For several decades, Kant scholars, inspired by the Groundwork false-promising example, have constructed consent-based criteria for using another merely as a means. Unfortunately, these consent-based accounts produce assessments that are both counter-intuitive and un-Kantian in relatively simple cases. This article investigates why these consent-based accounts fail and offers an alternative. The Groundwork false-promising example has encouraged a problematically narrow understanding of the conditions for using another merely as a means in virtue of the fact that the example involves a consent-sensitive duty. This article demonstrates that the scope of the prohibition on using another merely as a means includes both consent-sensitive and consent-insensitive duties and offers a duty-based account that reflects this.
The Predictive Role of Systemic Inflammatory Markers in the Development of Acute Kidney Failure and Mortality in Patients with Abdominal Trauma

Background: Abdominal trauma is defined as a variety of injuries to the abdominal wall, solid or hollow intra-abdominal organs, and various intra-abdominal vessels. Recently, there has been a significant amount of interest in the establishment of a reliable biomarker that can predict the outcome in patients with an abdominal injury. The purpose of this study is to confirm the predictive role of inflammatory biomarkers and underlying risk factors and the risk of acute kidney insufficiency (AKI) developing and mortality in abdominal trauma patients; Materials and methods: The current study was intended as an observational, analytical, retrospective cohort study and included all patients over 18 years of age with a diagnosis of abdominal trauma confirmed through a CT scan admitted to the County Emergency Clinical Hospital of Targu-Mureș, Romania between January 2017, and December 2021; Results: Non-survivor patients had a greater age (p = 0.02), as well as a higher prevalence of ischemic heart disease (IHD) (p = 0.007), history of myocardial infarction (MI) (p = 0.002), peripheral arterial disease (PAD) (p = 0.01), chronic kidney disease (CKD) (p = 0.01), and all risk factors (p = 0.0004 and p < 0.0001). In terms of injured organs, we have in the second group a higher incidence of kidney injury (p = 0.003) and hemoperitoneum (p = 0.008). Multivariate analysis showed a high baseline value for all inflammatory biomarkers that are independent predictors of adverse outcomes for all recruited patients. Furthermore, for all hospitalized patients, the history of MI (p = 0.03; p = 0.001; and p = 0.003), PAD (p = 0.01; p = 0.01; and p = 0.002), obesity (for all p < 0.0001), CKD (p < 0.001; p = 0.01; and p = 0.001), and kidney injury (p = 0.02; p = 0.004; and p = 0.01) were independent predictors of all outcomes. Moreover, IHD (p = 0.008 and p = 0.02), tobacco (p < 0.0001 and p = 0.02), and hemoperitoneum (p = 0.009 and p = 0.01) were predictors of mortality and composite endpoint, but not for AKI risk, as well as atrial fibrillation [AF] (p = 0.04) as predictors of the composite endpoint Conclusions: Higher monocyte to lymphocyte ratio (MLR), platelets to lymphocyte ratio (PLR), systemic inflammatory index (SII), neutrophil to lymphocyte ratios (NLR), aggregate inflammatory systemic index (AISI), and systemic inflammatory response index (SIRI) levels at admission, according to our data, highly predict AKI risk and death.
Flowfield measurements about a multi-element airfoil at high Reynolds numbers

This paper describes experimental data obtained with a multi-element airfoil at flight Reynolds numbers and lift coefficients including Clmax. The wind tunnel test was conducted in the NASA Langley Low Turbulence Pressure Tunnel as part of a cooperative effort between McDonnell Douglas Aerospace and NASA Langley. The airfoil model is a supercritical design configured with a leading-edge slat and a single-segment trailing-edge flap. Data include surface static-pressure distributions (integrated to obtain lift), drag data obtained with wake-rake surveys, and fbwfield surveys obtained with a flat-tube and five-hole probe at nine stations on the configuration's upper surface. Effects of variations in Reynolds number and flap gap on airfoil performance and flowfield survey data are presented.
Effects of a maximal cycling all-out anaerobic test on visual performance

ABSTRACT Clinical relevance All-out exercise may not impair all central nervous system processes, such as those related to visual-motor abilities, and may actually prove stimulatory to such tasks allowing athletes and sports conditioning specialists to develop strategies to take advantage of/mitigate the effects of such exercise on athletic performance. Background Despite research indicating that visual-motor abilities play a critical role in athletic performance, research has primarily focused on the effect of all-out exercise on processes along the motor pathway, such as resultant force production or simple cognitive tasks. Such research has neglected to investigate the effect of all-out exercise on visual tasks. When investigations on visual tasks are forthcoming, they focus on prolonged aerobic exercise, which is not the primary metabolic pathway for all, or even the majority of sports. Methods Sixty untrained males (experimental group; N = 30, control group; N = 30) completed a standardised six-item baseline sports vision test battery and one week later, the experimental participants returned to undertake a 30-second Wingate anaerobic test (30-WAnT) immediately followed by the same test battery. Results Significant (P < 0.05) improvements were found in accommodation facility, saccadic eye movement, speed of recognition, peripheral awareness and hand-eye coordination (P < 0.001 for all), but not visual memory (P = 0.242) following the 30-WAnT. Conclusions Although the mechanisms underlying these improvements in visual task performance have not yet been studied, this study suggests that simple anaerobic all-out exercise does not cause central- or brain-based fatigue impairing the oculomotor system but may rather provide “excitability” of the underlying motor cortex, motoneurons and/or corticofugal connections utilised in visual task response. It appears that the sweeping improvements in visual task performance elucidate the need for an intense anaerobic warm-up when training visual skills and when visual skills form an integral part of athletic performance.
Parameterization of the optical functions of amorphous materials in the interband region

A parameterization of the optical functions of amorphous semiconductors and insulators is presented in which the imaginary part of the dielectric function e2 is determined by multiplying the Tauc joint density of states by the e2 obtained from the Lorentz oscillator model. The real part of the dielectric function e1 is calculated from e2 using Kramers–Kronig integration. The parameters of this model are fit to n and k data for amorphous Si (2 data sets), SiO, As2S3, and Si3N4. Comparative fits are made with a similar parameterization presented earlier by Forouhi and Bloomer [Phys. Rev. B 34, 7018 (1986)]. In all cases, the new parameterization fits the data better.
Lithium Isotope Analyses of Inorganic Constituents from the Murchison Meteorite

Aqueous processes were important modifiers of solid matter during the early stages of solar system history. Lithium isotopes are sensitive indicators of such solid-liquid interactions because 7Li passes preferentially into solution and 6Li remains behind in the solid phase. Lithium isotope ratios of inorganic phases in the Murchison meteorite reveal that the value for the whole rock is simply the average of individual components with widely different isotopic compositions. 7Li content increases from chondrules to phyllosilicate-rich matrices to carbonates, as would be expected from the relative duration each component has spent during aqueous alteration on the parent asteroid.
Relación entre las funciones ejecutivas y el rendimiento académico en estudiantes de psicología

Funciones Ejecutivas (FE) (Memoria de Trabajo, Control Inhibitorio y Flexibilidad Cognitiva) están asociadas con el Rendimiento Académico (RA). Constituye un estudio no experimental, correlacional que relaciona la FE y RA en 185 estudiantes de psicología, seleccionados muestreo no probabilístico. Se aplicaron las pruebas de atención continua, memoria visuoespacial, variante del test de clasificación de tarjetas de Wisconsin, Juego de colores- efecto Stroop. Los resultados mostraron un efecto positivo entre memoria de trabajo y control inhibitorio y negativo de la flexibilidad cognitiva sobre el RA. Se puede concluir que la FE tiene un bajo nivel de predicción sobre el RA.
A Novel Categorization of Key Predictive Factors Impacting Hotels’ Online Ratings: A Case of Makkah

In the present Internet age, customers have turned to online booking websites to meet their demand for quality hotel services and convey their experiences. As hotels can survive and succeed by satisfying consumers and obtaining high online ratings, this research predicts the key factors impacting these ratings. The study analyzes online consumer review data gleaned from the popular Booking.com website for hotel ratings near the key religious heritage site in Makkah, Saudi Arabia. The research applies the four-factor theory due to its importance in studying consumer satisfaction and prior non-application to the hospitality and tourism industry. This theory extended the two-factor theory to report four distinct sets of factors: satisfiers, dissatisfiers, criticals, and neutrals. Accordingly, the present research presents a novel categorization of key predictive factors and enriches the literature, which categorized factors as either satisfiers or dissatisfiers. Consequently, facilities and comfort are critical factors, while cleanliness, staff, and location are satisfiers; the value for the money spent is dissatisfier; the availability of breakfast and restaurants are neutral factors. The hospitality industry, specifically the hotel industry, can focus on characteristics of the four distinct sets of factors; various nations can leverage the findings to boost their hospitality and tourism sectors.
Neurological Complications of Conventional and Novel Anticancer Treatments

Simple Summary Cancer survivors can experience neurological complications after exposure to anticancer therapy. Chemotherapy-induced peripheral neurotoxicity (CIPN), mainly consisting of sensory loss and neuropathic pain in hands and feet, is most commonly encountered. Cognitive impairment, although less frequent, is also a severe adverse event, significantly diminishing patients’ quality of life. The introduction of immunotherapy has resulted in durable remissions in several types of solid tumor malignancies, although severe neurological immune-related adverse events involving both the central and peripheral nervous system can occur in up to 10% of patients. We herein describe what it is currently known on the topic, and provide directions for future neuroprotection and symptomatic treatment studies. Abstract Various neurological complications, affecting both the central and peripheral nervous system, can frequently be experienced by cancer survivors after exposure to conventional chemotherapy, but also to modern immunotherapy. In this review, we provide an overview of the most well-known adverse events related to chemotherapy, with a focus on chemotherapy induced peripheral neurotoxicity, but we also address some emerging novel clinical entities related to cancer treatment, including chemotherapy-related cognitive impairment and immune-mediated adverse events. Unfortunately, efficacious curative or preventive treatment for all these neurological complications is still lacking. We provide a description of the possible mechanisms involved to drive future drug discovery in this field, both for symptomatic treatment and neuroprotection.
MiToS and King’s staging as clinical outcome measures in ALS: a retrospective analysis of the FORTITUDE-ALS trial

Abstract Objective To evaluate the Milano-Torino staging (MiToS) and King’s staging systems as potential outcome measures for clinical trials in amyotrophic lateral sclerosis (ALS) by assessing these outcomes in FORTITUDE-ALS. Methods This was a post hoc analysis of the phase 2b FORTITUDE-ALS trial (NCT03160898), a double-blind, randomized, dose-ranging, placebo-controlled, parallel-group study of reldesemtiv in patients with ALS. The treatment period was 12 weeks, with a follow-up assessment at week 16. Patients were retrospectively classified into MiToS and King’s stages. Outcomes were the mean time maintaining baseline stage and risk of progression from the baseline stage to a later stage. Results The full analysis set consisted of 456 patients randomized 3:1 (reldesemtiv n = 342, placebo n = 114) who received at least one dose of double-blind study drug and had at least one post-baseline assessment. At baseline, MiToS and King’s stages were balanced between the reldesemtiv and placebo groups: >99% of patients were in MiToS stage 0 or 1 and King’s stage 1, 2 or 3. Time of maintaining the baseline stage was similar in both groups, for each staging system. The two staging systems exhibited considerably disparate results for risk of progression from baseline to a later stage: hazard ratio (HR) = 0.62 (95% confidence interval [CI] 0.38, 0.99) for MiToS and HR = 0.96 (95% CI 0.63, 1.44) for King’s. Conclusion This exploratory analysis showed the feasibility of MiToS and King’s staging as potential outcome measures in ALS. Additional studies of these staging systems are needed to further explore their utility in ALS clinical trials.
The trash has gone – the trash mountain remains: a new look at the international design competition for the rehabilitation of the Hiriya landfill in Israel

Abstract Hiriya landfill, in central Israel, served Tel Aviv for 50 years and became a byword for neglect and ugliness until it was recently transformed from an environmental hazard, into a beautiful park. This article explores the idea and experience of waste, as concept and matter, and its representations in the 2004 international design competition for Hiriya’s rehabilitation. Addressing the global issue of rehabilitating wasted sites, the competition encouraged landscape architects to address a polluted past and outline new cultural and ethical meanings in the reclaimed public space. Drawing from unexplored textual and visual sources, and combining landscape architecture with cultural studies on waste, we reveal that few of the 14 proposals touched upon the complexity of waste, with its cultural, ethical and social attributes. The winning entry by Peter Latz turned the mound into a striking monument to trash, but minimised the visitors’ idea and experience of the waste itself.
Exogenous Application of Glycine Betaine on Sweet Cherry Tree (Prunus avium L.): Effects on Tree Physiology and Leaf Properties

Biostimulants, such as glycine betaine (GB), are a sustainable way to boost productivity and quality in fruit crops, even in adverse environment conditions. Sweet cherry (Prunus avium L.) is an important crop, which is very sensitive to abiotic stress. Known primarily for its fruits, its leaves are also rich in bioactive substances, which, however, still have no commercial value. There are no studies about the effects of GB exogenous application on biochemical parameters of sweet cherry leaves and few studies about effects in sweet cherry tree physiology. This study was conducted in a Portuguese sweet cherry commercial orchard. Lapins sweet cherry trees were treated with a commercial product based on GB, at two different concentrations (0.25% and 0.40%). The applications were performed at three different phenological stages, according to the BBCH (Biologische Bundesanstalt, Bundessortenamt und Chemische Industrie) scale: 77, 81 and 86 BBCH. Both GB treatments improved leaf water status, photosynthetic pigments, soluble solids content, total phenolic contents, and antioxidant activity, resulting in better leaf water status regulation, greater photosynthetic capacity, and higher antioxidant activity. These results shows that GB can benefit sweet cherry tree physiology and provide new opportunities for sweet cherry leaves valorisation.
Southern Hemisphere Annular Mode Variability and the Role of Optimal Nonmodal Growth

Abstract The southern annular mode is the leading mode of Southern Hemisphere circulation variability, the temporal evolution of which is characterized by large amplitudes and significant persistence. Previous investigators have suggested a positive feedback mechanism that explains some of this low-frequency variance. Here, a mechanism is proposed, involving transient nonmodal growths of the anomalies, that is at least as effective as the positive feedback mechanism in increasing the low-frequency variance of the southern annular mode. Using the vector autoregressive modeling technique, a number of linear inverse models of southern annular mode variability from National Centers for Environmental Prediction–Department of Energy (NCEP–DOE) Reanalysis 2 is derived. These models are then analyzed applying the ideas of the generalized stability theory. It is found that, as a consequence of the nonnormality of the system matrices, a significant increase in the low-frequency variance of the southern annular mode.