Miracle-dz/UniFAR-FTUs huggingface dataset:
Alleviation of adverse effects of nickel on growth and concentration of copper and manganese in wheat through foliar application of ascorbic acid

Abstract We investigated the role of ascorbic acid (AsA) to alleviate nickel (Ni) induced adverse effects on growth and concentration of Ni, copper (Cu), and manganese (Mn) in hydroponically grown wheat varieties viz. Galaxy, Punjab-2011, and FSD-08. Plants were exposed to five levels of Ni viz. 0, 5, 10, 15, and 20 mg L−1. After 1 week, AsA (1 mM) was sprayed onto the Ni-stressed plants. FSD-08 produced the maximum SDW with and without AsA compared to other varieties. FSD-08, Galaxy, and Punjab-2011 witnessed 2.61-, 2.83-, and 7.5-fold increases in SDW with AsA, respectively. Wheat plants contained the maximum Ni in shoots and roots with a Ni level of 20 mg L−1 irrespective of varieties. Nickel in shoots decreased with AsA witnessing 13, 12, and 10% decrease in FSD-08, Punjab-2011, and Galaxy, respectively. Nickel in roots of FSD-08 decreased by 18% while increased by 3.34-fold and 3.50-fold in Galaxy and Punjab-2011, respectively with AsA. Nickel decreased Cu in shoot and Mn in shoot and root while Cu in roots of all wheat varieties increased. It was concluded that AsA improved the growth of Ni-stressed and FSD-08 performed better by maintaining good growth and less Ni in shoots compared to other varieties. NOVELTY STATEMENT Exploiting plant internal mechanisms with foliar application of different organic substances have widely been investigated to decrease metal accumulation and their adverse effects on plants. However, the differential response of different varieties to metal accumulation in response to foliar application of ascorbic acid is not well documented. This study was conducted to investigate the effect of exogenous application of ascorbic acid on growth response, the concentration of Ni, Cu, and Mn in three wheat varieties.
Largely shared neural codes for biological and nonbiological observed movements but not for executed actions in monkey premotor areas

The neural processing of others' observed actions recruits a large network of brain regions (the action observation network, AON), in which frontal motor areas are thought to play a crucial role. Since the discovery of mirror neurons (MNs) in the ventral premotor cortex, it has been assumed that their activation was conditional upon the presentation of biological rather than nonbiological motion stimuli, supporting a form of direct visuomotor matching. Nonetheless, nonbiological observed movements have rarely been used as control stimuli to evaluate visual specificity, thereby leaving the issue of similarity among neural codes for executed actions and biological or nonbiological observed movements unresolved. Here, we addressed this issue by recording from two nodes of the AON that are attracting increasing interest, namely the ventro-rostral part of the dorsal premotor area F2 and the mesial pre-supplementary motor area F6 of macaques while they 1) executed a reaching-grasping task, 2) observed an experimenter performing the task, and 3) observed a nonbiological effector moving in the same context. Our findings revealed stronger neuronal responses to the observation of biological than nonbiological movement, but biological and nonbiological visual stimuli produced highly similar neural dynamics and relied on largely shared neural codes, which in turn remarkably differed from those associated with executed actions. These results indicate that, in highly familiar contexts, visuo-motor remapping processes in premotor areas hosting MNs are more complex and flexible than predicted by a direct visuomotor matching hypothesis.
Sepsis-induced immunosuppression is marked by an expansion of a highly suppressive repertoire of FOXP3 +T regulatory cells-expressing TIGIT.

BACKGROUND Although literature demonstrates that an increase in both the number and suppressive function of CD4+FOXP3+T regulatory cells (Tregs) during sepsis contributes to an immunosuppressed state, little is known about the identity of these cells. METHODS Using the sepsis mouse model of cecal ligation and puncture (CLP), we analysed the frequency and molecular signature of the TIGIT + and TIGIT- Tregs subsets by flow cytometry and qPCR. Additionally, ST2-/- and STAT6-/- mice were submitted to CLP or rIL-33 treatment to investigate the mechanism through which TIGIT+Tregs differentiate during sepsis. RESULTS Sepsis was marked by the sustained expansion of the highly suppressive TIGIT +Tregs subset, which expresses Helios, Neuropilin-1, and high levels of Tnfrsf18 and Pdcd1 at 15d after CLP. The increase of the TIGIT +Tregs was accompanied by higher susceptibility to nosocomial bacteria challenge, suggesting its involvement with post-sepsis immunosuppression. Mechanistically, we found that the ST2 deletion abrogated the expansion of the TIGIT+Treg subset during sepsis. Furthermore, the treatment with rIL-33 resulted in the expansion of TIGIT+Tregs depending on the STAT6 and M2 macrophages. CONCLUSIONS These findings demonstrated that only the TIGIT+Tregs remain stably expanded at the late phase of sepsis. Moreover, the expansion of TIGIT +Tregs is dependent on the IL-33/ST2/STAT6/M2 macrophages axis.
Investigation of the effects of thickness on the metal-insulator transition in vanadium dioxide nanocrystals, and development of a novel vanadium dioxide mott field-effect transistor

INVESTIGATION OF THE EFFECTS OF THICKNESS ON THE METAL-INSULATOR TRANSITION IN VANADIUM DIOXIDE NANOCRYSTALS, AND DEVELOPMENT OF A NOVEL VANADIUM DIOXIDE MOTT FIELD-EFFECT TRANSISTOR Mustafa Mohieldin Fadlelmula Fadlelseed M.S. in Materials Science and Nanotechnology Advisor: Talip Serkan Kasırga July 2017 Vanadium dioxide (VO2) is a material that has attracted a lot of attention for its prospective potential to be utilized in the field of electrical and ultrafast optical switching in one hand, and for the fundamental physics that can be revealed through studying this strongly correlated material on the other hand. One of the most attractive qualities of VO2 is the metal-insulator transition (MIT) which takes place slightly above room temperature in this material. Controlling such phase transition through external stimuli would open unprecedented avenues of electrical and optical applications. However, thin VO2 nanocrystal are required to overcome the limitation imposed thought the Thomas-Fermi screening length which limits the changes and the control that external electrical stimuli would have on any crystal that exceeds this length. The screening length in VO2 is known to be no more than 6 nm. Here, we avoided the use of epitaxial and sputtered films for the complications in such materials that arise from the stress due to lattice mismatch and the interdiffusion with substrates in epitaxial films, and the polycrystalline nature of sputtered films. In this work, vapor-phase grown VO2 nanocrystals are used instead. One reason behind this is that unlike epitaxial films vapor-phase grown VO2 nanocrystals can be released out of the growth substrate and transferred in order to eliminate the stress induced on the crystals due to adhesion to the substrate. The main shortcoming of this type of crystals, which is addressed thoroughly in this study, is that vapor-phase grown VO2 nanocrystals are produced with dimensions no less than 30 nm due to the lack of thickness control in physical vapor deposition technique.
Representative Sampling of the Via Assessment Suite for Adults

Abstract Character strengths have become a popular topic in personality research. A set of questionnaires has recently been developed as measures of character strengths: the VIA Inventory of Strengths-Revised, two 96-item short forms of that instrument, and two new measures called the Global Assessment of Character Strengths and Signature Strengths Survey. Collectively, these are referred to as the VIA Assessment Suite for Adults. Prior research has supported the reliability and validity of these measures. The current study extended those findings through a demographically stratified sample of 1,765 U.S. resident adults. Results indicated the scores were interchangeable across all three versions of the VIA-IS, irrespective of whether the items are all positively keyed or a mix of positive and negative items. In addition, the VIA-IS-R factor structure is also consistent with a previously identified three-factor model for the strengths. By freeing residual covariances, a model was developed for which adequate fit was replicable. This provided the foundation for demonstrating measurement invariance. The present study also explored differences in strengths across demographic categories and evaluated various approaches to identifying key (signature) strengths for the respondents. Recommendations on the use of the different instruments are provided.
Intraventricular mucin‐producing glioblastoma arising in the septum pellucidum at the frontal horn of the lateral ventricle: A case report

Glioblastoma (GBM) most commonly appears to be intraparenchymal tumor, and intraventricular GBMs are rarely reported. In previous reports, the sites of origin were not identified. Here, we report a rare case of intraventricular mucin‐producing GBM in a 73‐year‐old woman who had a strongly enhancing tumor in the right anterior horn of the lateral ventricle. The tumor had previously been identified one and a half years ago as a small asymptomatic lesion attached to the septum pellucidum. It had been documented to gradually enlarge during subsequent follow‐up examinations. The patient underwent a gross total resection of the tumor, and a soft and gelatinous mass was observed. The pathological diagnosis was compatible with GBM, and numerous tumor cells having cytoplasmic mucin vacuoles were observed. Genetic analysis revealed TP53 and NFKBIA deletions. The patient received postoperative concurrent chemotherapy with temozolomide and radiotherapy, followed by maintenance administration of temozolomide. A follow‐up examination seven months later detected an asymptomatic local recurrent lesion, which was treated with gamma‐knife therapy, followed by bevacizumab administration for six months. The patient has remained clinically well for five years following surgery. The origin of a rare tumor entity, intraventricular GBM, and the specific spatial and pathological findings in our case are discussed in this report.
Shared decision-making in the ICU from the perspective of physicians, nurses and patients: a qualitative interview study

Objective To identify views, experiences and needs for shared decision-making (SDM) in the intensive care unit (ICU) according to ICU physicians, ICU nurses and former ICU patients and their close family members. Design Qualitative study. Setting Two Dutch tertiary centres. Participants 19 interviews were held with 29 participants: seven with ICU physicians from two tertiary centres, five with ICU nurses from one tertiary centre and nine with former ICU patients, of whom seven brought one or two of their close family members who had been involved in the ICU stay. Results Three themes, encompassing a total of 16 categories, were identified pertaining to struggles of ICU physicians, needs of former ICU patients and their family members and the preferred role of ICU nurses. The main struggles ICU physicians encountered with SDM include uncertainty about long-term health outcomes, time constraints, feeling pressure because of having final responsibility and a fear of losing control. Former patients and family members mainly expressed aspects they missed, such as not feeling included in ICU treatment decisions and a lack of information about long-term outcomes and recovery. ICU nurses reported mainly opportunities to strengthen their role in incorporating non-medical information in the ICU decision-making process and as liaison between physicians and patients and family. Conclusions Interviewed stakeholders reported struggles, needs and an elucidation of their current and preferred role in the SDM process in the ICU. This study signals an essential need for more long-term outcome information, a more informal inclusion of patients and their family members in decision-making processes and a more substantial role for ICU nurses to integrate patients’ values and needs in the decision-making process.
The Experience of Grandparenting Young Children

ABSTRACT This study examines the experience of grandparents providing regular childcare to their young grandchildren in China. Due to unique cultural and social factors, regular childcare provided by grandparents is becoming increasingly common in China. Unfortunately, published research on this topic does not provide a sufficient understanding of the experiences of grandparents who provide the regular care and the impact this has on their life. A qualitative, cross-sectional study was conducted in an urban village setting in Changsha China, where participants (N = 11) were recruited using purposive sampling. Data were collected between April 2019 and June 2019 and thematically analyzed using a seven-step modified procedure established by Colaizzi. Three key themes were identified: (1) Dominant factors motivating grandparenting; (2) Sweet burden of grandparenting; and, (3) Unmet needs. Study findings showed that while the Chinese grandparents perceived value and benefits to providing regular childcare, there are also significant challenges that need to be addressed. Interventions at a household and community level can be implemented to improve their childcare role.
The influence of jaw-muscle fibre-type phenotypes on estimating maximum muscle and bite forces in primates

Numerous anthropological studies have been aimed at estimating jaw-adductor muscle forces, which, in turn, are used to estimate bite force. While primate jaw adductors show considerable intra- and intermuscular heterogeneity in fibre types, studies generally model jaw-muscle forces by treating the jaw adductors as either homogeneously slow or homogeneously fast muscles. Here, we provide a novel extension of such studies by integrating fibre architecture, fibre types and fibre-specific tensions to estimate maximum muscle forces in the masseter and temporalis of five anthropoid primates: Sapajus apella (N = 3), Cercocebus atys (N = 4), Macaca fascicularis (N = 3), Gorilla gorilla (N = 1) and Pan troglodytes (N = 2). We calculated maximum muscle forces by proportionally adjusting muscle physiological cross-sectional areas by their fibre types and associated specific tensions. Our results show that the jaw adductors of our sample ubiquitously express MHC α-cardiac, which has low specific tension, and hybrid fibres. We find that treating the jaw adductors as either homogeneously slow or fast muscles potentially overestimates average maximum muscle forces by as much as approximately 44%. Including fibre types and their specific tensions is thus likely to improve jaw-muscle and bite force estimates in primates.
Molar biomechanical function in South African hominins Australopithecus africanus and Paranthropus robustus

Diet is a driving force in human evolution. Two species of Plio-Pleistocene hominins, Paranthropus robustus and Australopithecus africanus, have derived craniomandibular and dental morphologies which are often interpreted as P. robustus having a more biomechanically challenging diet. While dietary reconstructions based on dental microwear generally support this, they show extensive dietary overlap between species, and craniomandibular and dental biomechanical analyses can yield contradictory results. Using methods from anthropology and engineering (i.e. anthroengineering), we quantified the molar biomechanical performance of these hominins to investigate possible dietary differences between them. Thirty-one lower second molars were 3D printed and used to fracture gelatine blocks, and Bayesian generalized linear models were used to investigate the relationship between species and tooth wear, size and shape, and biomechanical performance. Our results demonstrate that P. robustus required more force and energy to fracture blocks but had a higher force transmission rate. Considering previous dietary reconstructions, we propose three evolutionary scenarios concerning the dietary ecologies of these hominins. These evolutionary scenarios cannot be reached by investigating morphological differences in isolation, but require combining several lines of evidence. This highlights the need for a holistic approach to reconstructing hominin dietary ecology.
What does ‘toughness’ look like? An examination of the breakdown of young and mature leaves under cyclical loading

The material property of leaf toughness is considered the crucial mechanical challenge facing folivorous primates. Mature leaves have higher recorded toughness values than young leaves on average, leading to many assumptions about the patterning of food breakdown that follow a tough/not-tough dichotomy. We tested three hypotheses about how leaves break down under repetitive loading cycles, predicting that mature leaves (i) experience more force during simulated occlusal loads, (ii) more effectively resist fragmentation into small pieces, and (iii) show a more gradual decline in resistance over consecutive cycles than young leaves. Under displacement control using a mechanical testing system, we subjected young and mature leaves to 20 cycles of axial loading using interlocking steel wedges, then collected and quantified the size of the leaf fragments. While we found that mature leaves experienced more overall force than young leaves (p < 0.001), they also shattered into smaller pieces (p = 0.004) and showed a steeper decline in their resistance to the cycles over the course of a test (p < 0.01). These results suggest that putatively ‘tougher’ foods (i.e. mature versus young leaves) do not necessarily resist fragmentation as commonly assumed. The current tough/not-tough paradigm of primate foods may not accurately reflect how leaves break down during masticatory behaviour.
ThermISRnet: an efficient thermal image super-resolution network

Abstract. The prime limitation of optical sensors is the need for external sources of illumination while capturing the scene. This prevents them from recognizing objects in extreme conditions, such as insufficient illumination or severe weather (e.g., under fog or smoke). The thermal imaging sensors have been introduced to circumvent this deficiency, which acquires the image based on thermal radiation emitted by the objects. The technological advancement in thermal imaging enables the visualization of objects beyond the visible range that promotes its use in many principal applications, such as military, medical, agriculture, etc. However, hardware point of view, the cost of a thermal camera is prohibitively higher than that of an equivalent optical sensor. This led to employ software-driven approaches called super-resolution (SR) to enhance the resolution of given thermal images. We propose a deep neural network architecture referred to as “ThermISRnet” as the extension of our earlier winner architecture in the Perception Beyond the Visible Spectrum (PBVS) thermal SR challenge. We use a progressive upscaling strategy with asymmetrical residual learning in the network, which is computationally efficient for different upscaling factors such as ×2, ×3, and ×4. The proposed architecture consists of different modules for low- and high-frequency feature extraction along with upsampling blocks. The effectiveness of the proposed architecture in ThermISRnet is verified by evaluating it with different datasets. The obtained results indicate superior performance as compared to other state-of-the-art SR methods.
Seasonal trend of Eutetranychus orientalis in Moroccan citrus orchards and its potential control by Neoseiulus californicus and Stethorus punctillum

Abstract Citrus brown mite, Eutetranychus orientalis (Klein), known as major pest of citrus crops in different countries, was considered as a quarantine pest in Morocco. This pest is currently among the most potential enemies of Moroccan arboriculturists following the increasing ineffectiveness of the majority of acaricides used in conventional orchards. The present study was designed to collect and morphologically identify specimens from 31 orchards in the five main production regions of Morocco; to study the population dynamics of this pest in Taroudant as well as the molecular identification of a Phytoseiid considered as a potential predator using the mitochondrial 12S rRNA gene. Morphological description confirmed that the collected adult females from all orchards in the five regions belong to E. orientalis. Thus, this exotic pest has invaded all citrus growing regions since its introduction. In the Souss region, two significant peaks of population outbreaks of this pest were observed. A first peak from November until the end of December 2017 and in winter, a second peak is recorded in early autumn 2018. Thereafter, mite infestations remained at lower levels throughout the summer. In addition, it appears that eggs represented between 50 to 88.7% of population in spring and winter seasons respectively, but percentage of adult females does not exceed 2.3% in autumn and winter seasons. Adult females of Neoseiulus californicus, larvae of Stethorus punctillum, were more abundant and very active on orange leaves and weeds during period of observation. Molecular analysis using 12S ribosomal RNA gene confirmed that the best query coverage 99.23% (E-value = 5e-176) with 99% of recovery identical to N. californicus. The phylogenetic tree obtained from comparison of the specimens' generated DNA sequences with other individuals from Neoseiulus genus revealed the relationship with species N. californicus. These results suggest that orchard management will favour the plant cover associated with citrus trees and thus ensure sustainability, diversity and high density of phytoseiides and other predatory insects. This auxiliary fauna, like N. californicus, S. punctillum, will be able to control spider mites, as well as other phytophagous insects and keep them below damaging levels in citrus orchards in the Souss region.
Low-alpine vegetation in Gutulia National Park, Engerdal, Hedmark, Norway, and its relation to the environment

Abstract A reference site for vegetational and ecological monitoring of low-alpine vegetation has been established in Gutulia National Park, Engerdal, Hedmark, Norway. Fifty vegetation plots, each 1 m2, were distributed randomly along four open transects. Species abundance was recorded as frequency in 16 subplots. Each plot was supplied with measurements of 26 environmental variables. The first axes of DCA and LNMDS ordinations were closely similar. The first DCA axis was interpreted as a complex snow cover gradient. Several environmental variables varied along this gradient, among them unevenness, soil moisture and soil nutrient status. The cover of the bottom layer varied along the complex-gradient. DCA axis 2 was interpreted as a microclimatic gradient. Partitioning of the environmental· and spatial variation in species composition showed that the spatial variation in the data set was rather low. Monitoring alpine vegetation is considered important since alpine ecosystems may be particularly vulnerable to airborne pollution.