Miracle-dz/UniFAR-FTUs huggingface dataset:
Using Supply-Side-Chain Functions to Enhance Channel Performance (Revised Version)

The purpose of this study is to seek feasible supply-side-chain (SSC) functions/ strategies to promote channel performance to diminish the hazard of losing efficiencies in the garment industry. We utilize the LISREL model to examine cause and effects relationship among supply-side-chain functions, service innovation and channel performance. Since the relationship between SSC function and service innovation (including supportive innovation and interactive innovation) is scant, and service innovation can effective contribute to channel performance, that the need of this study is then emerging. We employ quota sampling method to survey 400 customers and clerks from Taiwan’s top 10 garment companies, in terms of net assets, on the basis of printed questionnaires. SSC leanness in garment companies can mainly promote channel performance from the channel of supportive innovation. The supportive innovation is supposed to appear after the long usage and not discovered at the initial time period. Then, the invisible supportive innovation is supposed to achieve a certain level of opportunity benefit to restart the companies.
Design and Simulation of a Nanoscale Threshold-Logic Multiplier

– Multiplication is one of the most important operations in microprocessors and digital signal processing systems. Different multiplier architectures have been proposed in the literature. One of the most widely used architecture is the Wallace tree multiplier. This multiplier is known for its high speed. However, it occupies a large area. In this paper, we used Threshold Logic Gates instead of conventional logic gates to reduce the area. The multiplier was designed in 65nm CMOS technology, and achieved 28% reduction in the number of transistors compared to the one with conventional logic gates. It also achieved a lower power-delay-product.
THE PREVALENCE OF COSMETIC SURGERY AMONG FEMALE UNIVERSITY STUDENTS IN RIYADH, SAUDI ARABIA

Objectives: This study aimed to estimate the prevalence of cosmetic surgery among Saudi female University students and to assess their experiences and attitudes toward cosmetic surgery. Methods: During 2018, a cross-sectional comparative study at Riyadh Universities. Initially, a simple random sampling technique was employed to select relevant colleges from within the Universities. In the second stage, two to three courses from each graduating class were randomly selected. Finally, using the systematic random sampling strategy, each 4th student in the class was selected until the desired sample size was achieved. Two selfadministered questionnaires were used for data collection: the Multidimensional Body-Self Relations Questionnaire and the Cosmetic Surgery Attitudes Questionnaire. Results: The response rate was 99.3%. Thirteen students (2.2%) had received cosmetic surgery, and 11.4% were potential cosmetic surgery candidates. Fifty-two percent of students agreed that the cost of cosmetic surgery would be a waste of money; however, 15.3% supported those who wanted to undergo surgery. The highest mean score of 3.93 + 0.47 was recorded for appearance orientation followed by appearance evaluation (3.86 + 0.68). Students who had been subjected to cosmetic surgery were significantly more concerned about overweight preoccupation (p < 0.05). Almost half of the students who had undergone cosmetic surgery agreed that social media had influenced their decisions. Conclusions: In this study, a small number of undergraduate University students had been subjected to cosmetic surgery, and 16% indicated that they would consider surgery later in life. Social media has a major impact on decision-making regarding cosmetic surgery.
Effect of Crude Ethanolic Extracts from Bottle Brush (Callistemon viminalis) against Leaf Spot Fungi and Their Phytotoxicity on Lettuce (Lactuca sativa L.)

In response to the public concern about environmental problems as well as fungicide residues on agricultural produces especially leaf vegetables, we investigated the potential use of crude extracts from bottle brush (C. viminalis) leaves against leaf spot fungi and their phytotoxicity on lettuce grown in hydroponics. Yield, total phenolic and flavonoid contents of the extract were also evaluated. Regarding the in vitro antifungal assay using poisoned food technique, 3×3 factorial in Completely Randomized Design (CRD) was employed with three replicates. Factor A was 3 crude extracts (50% ethanol, 70% ethanol and 95% ethanol crude extract) while factor B was the 3 concentrations (0, 5,000 and 50,000 ppm) of crude extracts. Results showed that all three crude extracts were significantly effective in inhibiting the mycelial growth and sporulation of leaf spot fungi (Alternaria sp. and Curvalaria sp.). There was a significant interaction between all extracts and their concentration regarding inhibition percent. Increase in crude extract concentrations resulted in a marked increase in their inhibition. The concentration of 50,000 ppm gave the highest effectiveness. For phytotoxicity test, all tested crude extracts did not give any negative effects either on seed germination or growth of lettuce grown in hydroponics. Interestingly, growth promotion about 30 percent was achieved on this regard. Based on quantitative assay, the highest yield of crude extract was obtained from 95% ethanol solvent. Highest total phenolic and flavonoid contents were detected at the highest concentration of all crude extracts.
STUDY OF POWER DISSPATION IN AN INTERCONNECTED NETWORK OF A MICROPROCESSOR

--Interconnect power is dynamic power dissipation due to interconnect capacitance switching. This paper describes how much power is consumed by interconnections, Future generation trends, how to reduce interconnect power. Power is becoming a major design issue. The analysis showed that interconnect power consumed 50% of the dynamic power and 90% of the power is consumed by only 10% of the interconnections. Interconnect design is not POWER AWARE! Relations of interconnect power to wire length distribution and hierarchy level of nets were examined. The power-aware router algorithm was tested on synthesized blocks, demonstrating average saving of 14% in the dynamic power consumption without timing degradation or area increase. The results demonstrate the obtainable benefits of tuning physical design algorithms to save power.
Both mature KIR and immature KIR NK cells control pediatric acute B-cell precursor leukemia in NOD.Cg-Prkdc IL2rg/Sz mice

University Children’s Hospital, Department of Pediatric Hematology and Oncology, Eberhard Karls University, Tuebingen, Germany; Department of Internal Medicine II, Division of Hematology and Oncology, Eberhard Karls University, Tuebingen, Germany; University Medical Center, 3 Department of Medicine/Hematology, Internal Oncology and Pneumology, Johannes Gutenberg-University, Mainz, Germany; University Children’s Hospital, Department for Pediatric Hematology and Oncology, Campus Virchow Klinikum, Charité Berlin, Berlin, Germany; University of Regensburg, Department of Internal Medicine III, Regensburg, Germany; Viral Immunobiology, Institute of Experimental Immunology, University of Zürich, Switzerland; and University Children’s Hospital, Department of Pediatric Intensive Care, Basel, Switzerland
OUTPATIENT INFLUENZA SURVEILLANCE: BRIDGING THE GAP BETWEEN CLINICAL MEDICINE AND PUBLIC HEALTH by

Influenza causes considerable morbidity and mortality each year. Surveillance efforts in the United States are helpful for describing the influenza season (October through mid-May) but, due to reporting lags, are limited in the ability to provide early notification of the epidemic onset in a community. Here, we summarize the health impact of influenza and describe how influenza-like illness surveillance is currently conducted in outpatient clinics that contribute data to the Sentinel Providers Network in Utah. We compared data collection methods and found that clinics using automated methods had more complete data reporting with substantially lower personnel effort compared with clinics using traditional methods. Next, we describe the development of an outpatient surveillance system that applied statistical process control to the percentage of daily visits with a positive rapid influenza test. This system was developed using 4 years of historical data stored in discrete, searchable fields contained in the electronic medical records of outpatients visiting 10 clinics in the Utah Health Research Network (a clinic system contributing data to the Utah Sentinel Providers Network). Relative to traditional surveillance of influenza-like illness, rapid test positivity generated earlier signals of clinical influenza activity and had fewer false positive signals. Finally, we implemented our surveillance system prospectively to assess its ability to generate early alerts in real time. The real-time implementation generated a signal 19 days prior to the epidemic onset, which was similar to the median of 16 days estimated using historical data. We describe the impact on clinician behaviors related to influenza prevention that was associated with early notification generated by this novel surveillance system, and present lessons learned from the first year of real-time implementation. In summary, our surveillance system generated a signal 2 3 weeks before the epidemic onset in analysis of both historical data and real-time implementation. This compared favorably with reports by other authors of early signals generated using alternatives to traditional surveillance of outpatient influenza-like illness. The availability of rapid test results in the electronic medical record and simplicity of statistical process control methodology make this surveillance system relatively easy to implement in a clinical setting.
Acute neurophysiological effects of neuromuscular manual therapy in intensive care unit

With the term “severe acquired brain injury” (ABI) we mean a damage, of traumatic or other nature (hypoxic, infective, vascular) origin, capable of inducing a coma state (Glasgow Coma Scale GCS=<8), or moto-sensory impairement, and/or cognitivecomportamental impairement, which involve serious disability [2]. The overall recovery after a TBI is a direct consequence of physical, cognitive and behavioral residual abilities. The aim of our study is to collect clinical and rehabilitative datas, through the application of a neuromuscular manual therapy protocol on a selected sample of patients recovered in intensive care Unit. Patients included in the blind randomized trial were recruited following specific inclusion and exclusion criteria and then they underwent a therapeutical protocol of neuromuscular manual therapy (NMT). Vital parameters considered (HR, BR, O2S and BP) were monitored using advanced digital systems deriving from the usage of specific invasive and no-invasive medical aids present in the Intensive Care department. Patients underwent neuromuscular manual therapy sessions executed one a day for 7 to 10 sessions per patient, vital parameters of patients were collected The results of this study demonstrated a mean reduction in heart rate, a reduction in systolic blood pressure, a reduction in diastolic blood pressure, a reduction in mean arterial pressure, an average decrease in respiratory rate and finally a slight increase in the oxygen’s saturation
OPTH_A_279607 3575..3582

1School of Medicine, Johns Hopkins University, Baltimore, MD, USA; 2Department of Radiation Oncology, UAMS Winthrop P. Rockefeller Cancer Institute, Little Rock, AR, USA; 3The Wilmer Eye Institute, Bethesda, MD, USA Importance: Ophthalmology patients are seeking medical advice on social media websites like Reddit, where users are able to post comments and discuss issues pertaining to different topics that are organized in ‘subreddits’. Understanding which issues are most pertinent will guide ophthalmic providers in delivering more effective patient education. Methods: This cross-sectional study assessed a systematic sample of the first 22 posts and their top 3 comments from each month since January 27th, 2019, the subreddit’s creation. Information was gathered from reddit.com/r/eyetriage in October 2019 and analyzed in November 2019. Main Outcomes: The posts were characterized by date and time, inclusion of an image, type, content, emotional tone, and number of upvotes and comments. The comments were categorized based on content, emotional tone, time of comment, and user background. Post and comment content codes were categorized in an iterative manner with differences resolved by author consensus. Categorical statistics were compiled. Results: Two hundred posts and 456 comments were analyzed since the creation of r/ eyetriage, a forum created exclusively for patients to seek advice from health-care professionals. Twenty-six (13%) of the total posts included an image. On average, comments received 1.76 ± 2.17 upvotes along with 4.50 ± 4.47 replies. The most common content codes among the posts were 42 (21.0%) seeking diagnoses, 23 (11.5%) surgical complications, and 13 (6.50%) alternative medication options. Eighty-two (41%) posts conveyed a clear emotional tone, most notably 11 (13.4%) with anxiety and 10 (12.2%) with worry. The top comments came from 165 (36.2%) self-identified patients, 151 (33.1%) optometrists, and 49 (10.8%) ophthalmologists. The top comment codes for replies included 158 (34.7%) with treatment advice, 70 (15.4%) with advice deferred to follow-up appointment with other health-care specialists, and 60 (13.2%) with sharing information. Conclusions: Patients are asking ophthalmology-related questions on the Eye Triage subreddit, and they are more likely to receive information from other patients or optometrists than from self-identified ophthalmologists. When emotions were revealed, patients were often anxious and worried. Opportunities exist for ophthalmologists to take a more active role on this subreddit and help educate patients.
AIR POLLUTION AS A CONTRIBUTING RISK FACTOR OF RELAPSES AND CASES OF MULTIPLE SCLEROSIS

C. Zhukovsky1, M. -A. Bind2, I. Boström3, A. -M. Landtblom4 Department of Neurosciences, Uppsala University, 3 Husargatan Str. , Uppsala, SE-752 36, Sweden Department of Statistics, Harvard University, MA 02138, Massachusetts Hall, Cambridge, USA Departments of Neurology and Clinical and Experimental Medicine, Linköping University, SE-581 83, Linköping, Sweden Uppsala University Hospital, SE-751 85, Uppsala, Sweden
Cutting Edge: Infection of Mice Lacking the Common Cytokine Receptor γ-Chain (γc) Reveals an Unexpected Role for CD4+ T Lymphocytes in Early IFN-γ-Dependent Resistance to Toxoplasma gondii

Mice lacking the common cytokine receptor γ-chain (γc) gene exhibit defective development of NK cells and CD8+ T cells and greatly diminished production of IFN-γ. Because resistance of SCID mice to Toxoplasma gondii requires IL-12-dependent IFN-γ production by NK cells, we expected that γc-deficient mice would succumb rapidly to the parasite. Surprisingly, however, most γc-deficient mice survived the acute phase of T. gondii infection. As in wild-type mice, this resistance required IL-12 and IFN-γ; nevertheless, whereas wild-type mice depleted of CD4+ T cells survived, anti-CD4+ treated γc-deficient mice displayed diminished production of IFN-γ and all succumbed to acute infection. These data not only reveal a role for CD4+ T lymphocytes in IFN-γ-dependent host defense but also establish SCID and γc-deficient mice as powerful complementary tools for assessing the function of NK vs CD4+ T cells in immunopathophysiologic responses.
SEMINAR FOR PHYSICIANS

Introduction. Rapid diagnosis of acute myocardial infarction is essential for proper treatment and reduction of patient mortality. Electrocardiography plays an important role in its diagnosis. Acute myocardial infarction with ST segment elevation requires urgent reperfusion therapy, that is, primary percutaneous coronary revascularization. A small number of patients with acute myocardial infarction have ST segment depression in one or more leads, whereas ST segment elevation in augmented vector right the electrocardiogram is characteristic for a myocardial infarction without ST elevation, but the clinical course and the severity of disease correspond to the anterior myocardial infarction with ST segment elevation. De Winter T-wave electrocardiography. One of these forms is known as de Winter T-wave pattern, characterized by ST segment depression at the J-point (> 1 mm) in the precordial leads, the absence of ST segment elevation in the precordial leads, high peaked and symmetrical T-waves in the precordial leads and, in most cases, mild ST segment elevation (0.5 mm to 1 mm) in the augmented vector right. These patients have occlusion of the left main coronary artery, occlusion of the proximal segment of the anterior descending artery, or a severe multivessel coronary disease. Patients with this electrocardiographic pattern, which is equivalent to acute myocardial infarction with ST segment elevation, require consideration of emergency reperfusion therapy due to high mortality, compared to other patients with acute myocardial infarction without ST elevation. Primary percutaneous intervention is recommended, or if there is no catheterization laboratory nearby, fibrinolytic therapy may be considered. Because of the lack of clear recommendations, treatment decisions are made individually, from case to case. Conclusion. We need large prospective studies with this specific electrocardiographic pattern to provide quick recognition and proper treatment of the anterior myocardial infarction with ST elevation.
COPD_A_292666 825..834

*These authors contributed equally to this work Background: We aimed to investigate the association between red cell index (RCI) and the severity of Chronic Obstructive Pulmonary Disease (COPD), and compare predictive value of RCI, neutrophil–lymphocyte ratio (NLR) and platelet–lymphocyte ratio (PLR) for the severity of COPD. Methods: A total of 207 participants were recruited (100 COPD patients and 107 healthy controls). COPD patients were divided into two groups according to the optimal cut-off value of RCI determined by the receiver operating characteristic (ROC) curve. Pearson’s correlation test, logistic regression analysis and other tests were performed. Results: Compared with low RCI group, the forced expiration volume in 1 second (FEV1) and FEV1 in percent of the predicted value (FEV1%) in high RCI group were lower (p = 0.016, p = 0.001). There was a negative correlation between RCI and FEV1% (r = −0.302, p = 0.004), while no correlation between FEV1% and NLR as well as PLR were found. RCI showed higher predictive value than NLR and PLR for predicting Global Initiative for Chronic Obstructive Lung Disease classification (GOLD), with a cut-off value of 1.75 and area under the curve (AUC) of 0.729 (p = 0.001). Multivariate logistic regression analysis proved that RCI was an independent factor for lung function in COPD patients (odds ratio [OR] = 4.27, 95% CI: 1.57–11.63, p = 0.004). Conclusion: RCI is a novel biomarker that can better assess pulmonary function and severity of COPD than NLR and PLR. Higher RCI is related to deterioration of pulmonary function.
Nr5a2 promotes tumor growth and metastasis of gastric cancer AGS cells by Wnt/beta-catenin signaling

Purpose: Nr5a2 (nuclear receptor subfamily 5 group A member 2, also known as LRH-1), which belongs to the NR5A (Ftz-F1) subfamily of nuclear receptors, is a key regulator in stem cell pluripotency and the development of several types of cancer. However, the data are controversial. Since Nr5a2 plays different roles in multiple types of cancer and the function of Nr5a2 in gastric cancer (GC) has not been revealed, we studied the role and molecular mechanism of Nr5a2 in GC. Methods: In this study, we have investigated the effect of Nr5a2 on tumor growth and metastasis by in vivo and in vitro models. Results: The results showed that knockdown of Nr5a2 could inhibit cell proliferation via arresting the cell cycle in the G2/M phase and suppress cell mobility through preventing the epithelial-mesenchymal transition (EMT) process in AGS cells. In addition, knockdown of Nr5a2 could suppress tumorigenesis and metastasis of AGS cells in vivo. We also demonstrated that knockdown of Nr5a2 inhibited cellular proliferation and mobility by suppressing the Wnt/beta-catenin signaling pathway. Conclusion: Nr5a2 may act as an oncogene in GC development. The EMT process and the Wnt/ beta-catenin signaling pathway play an important role in the Nr5a2 GC development.
This is a repository copy of Exploring the effects of positive and negative emotions on eating behaviours in children and young adults. White Rose Research Online URL for this paper: https://eprints.whiterose.ac.uk/161613/

It is well established that stress can elicit change in a range of eating behaviours, however, less is known about these effects in children and young adults. In addition, there is a growing interest in investigating the role of positive as well as negative emotions as triggers of food intake in children. Therefore, the current study aimed to explore the relationship between positive and negative emotions and eating behaviour in children (aged 9-10 years old) and young adults together with the moderating effects of eating styles (emotional and external eating). A questionnaire design was used to investigate the effects of positive and negative emotions on snacking responses in children and young adults (children, N = 53, young adults, N = 72). Eating styles were assessed using the Dutch Eating Behaviour Questionnaire. We found that children reported wanting to eat more snacks in response to positive emotions, while young adults reported wanting to eat more snacks in response to negative emotions. Emotional and external eating styles moderated the positive and negative emotions – eating response relationship. Future research should include both positive and negative emotions when examining the influence of stress and emotions on eating, particularly when exploring the triggers of food intake amongst children.
University of Birmingham A Randomized Controlled Trial to Assess the Impact of Clinical Pharmacy Interventions on Treatment Outcomes, Health Related Quality of Life and Medication Adherence Among Hepatitis C Patients

Citation for published version (Harvard): Ali, S, Ali, M, Paudyal, V, Rasheed, F, Ullah, S, Haque, S & Ur-Rehman, T 2019, 'A Randomized Controlled Trial to Assess the Impact of Clinical Pharmacy Interventions on Treatment Outcomes, Health Related Quality of Life and Medication Adherence Among Hepatitis C Patients', Patient preference and adherence, vol. 13, pp. 20892100. https://doi.org/10.2147/PPA.S224937