Miracle-dz/UniFAR-FTUs huggingface dataset:
INFLUENCE OF PRODUCT ATTRIBUTES AND VARIETY SEEKING ON BRAND SWITCHING BEHAVIOR OF XIAOMI SMARTPHONE USERS

The high number of smartphone users in Indonesia has made the country a potential target market for smartphone companies. This makes consumers in this sector more selective in choosing a smartphone brand. This selective behavior of consumers is a sign that there can be brand switching behavior by consumers due to unfulfilled consumer needs and desires. This study aims to determine the effect of Product Attributes and Variety Seeking on Brand Switching Behavior of Xiaomi smartphone by UPN Veteran East Java students. This study uses a quantitative method using 81 people as a research sample. The number of respondents was determined using a non-probability sampling method with purposive sampling technique. The data collection method was carried out through conventional questionnaire distribution and measured using a Likert scale. The analytical tool used in this research is Partial Least Square (PLS). The results of this study indicate that the variables of product attributes and variety seeking have a significant influence on brand switching of Xiaomi smartphone brands by students of the National Development University "Veteran" East Java.
Human Acellular Amniotic Membrane as Skin Substitute and Biological Scaffold: A Review of Its Preparation, Preclinical Research, and Clinical Application

Human acellular amniotic membrane (HAAM) has emerged as a promising tool in the field of regenerative medicine, particularly for wound healing and tissue regeneration. HAAM provides a natural biological scaffold with low immunogenicity and good anti-infective and anti-scarring results. Despite its potential, the clinic application of HAAM faces challenges, particularly with respect to the preparation methods and its low mechanical strength. This review provides a comprehensive overview of HAAM, covering its preparation, sterilization, preclinical research, and clinical applications. This review also discusses promising decellularization and sterilization methods, such as Supercritical Carbon Dioxide (SC-CO2), and the need for further research into the regenerative mechanisms of HAAM. In addition, we discuss the potential of HAAM as a skin dressing and cell delivery system in preclinical research and clinical applications. Both the safety and effectiveness of HAAM have been validated by extensive research, which provides a robust foundation for its clinical application.
Using Cryopreserved Plasmodium falciparum Sporozoites in a Humanized Mouse Model to Study Early Malaria Infection Processes and Test Prophylactic Treatments

In addition to vector control, long-lasting insecticidal nets and case management, the prevention of infection through vaccination and/or chemoprevention are playing an increasing role in the drive to eradicate malaria. These preventative approaches represent opportunities for improvement: new drugs may be discovered that target the early infectious stages of the Plasmodium parasite in the liver (rather than the symptomatic, abundant blood stage), and new, exciting vaccination technologies have recently been validated (using mRNA or novel adjuvants). Exploiting these possibilities requires the availability of humanized mouse models that support P. falciparum infection yet avoid the hazardous use of infectious mosquitoes. Here, we show that commercially available P. falciparum sporozoites and FRG mice carrying human hepatocytes and red blood cells faithfully recapitulate the early human malaria disease process, presenting an opportunity to use this model for the evaluation of prophylactic treatments with a novel mode of action.
Challenges in addressing student difficulties with basics and change of basis for two-state quantum systems using a multiple-choice question sequence in online and in-person classes

Research-validated multiple-choice questions comprise an easy-to-implement instructional tool for scaffolding student learning and providing formative assessment of students’ knowledge. We present findings from the implementation of a research-validated multiple-choice question sequence on the basics of two-state quantum systems, including inner products, outer products, translation between Dirac notation and matrix representation in a particular basis, and change of basis. This study was conducted in an advanced undergraduate quantum mechanics course, in both online and in-person learning environments, across three years. For each cohort, students had their learning assessed after traditional lecture-based instruction in relevant concepts before engaging with the multiple-choice question sequence. Their performance was evaluated again afterward with a similar assessment and compared to their earlier performance. We analyze, compare, and discuss the trends observed in the three implementations.
Late Quaternary monsoonal climate and related variations in paleoproductivity and alkenone-derived sea-surface temperatures in the western Arabian Sea.

20 Introduetion 20 Monsoon Meteorology and Hydrographie Setting 22 Material and Methods 24 Material 24 Methods 24 Stratigraphy , 26 Results 28 Western Arabian Sea, Open Oeean: GeoB 3005 28 Western Arabian Sea, Continental Slope off Oman: ODP Site 723 31 Eastern Arabian Sea, Open Ocean: MD 900963 . 31 Cross-Speetral Analysis 34 Diseussion 36 Group 1: SW Monsoon Wind Strength and Upwelling Intensity in the Western Arabian Sea (-6,4 to -9.6 kyr) 37 Group 2: Paleoproduetivity in the Western Arabian Sea (-10.9 to +9.6 kyr) 39 Group 3: Paleoproductivity in the Eastern Arabian Sea (+8.3 to +6.4 kyr) 41 Implieations for the Sedimentary TOC and C37 Alkenone Signal in the Arabian Sea . 42 Conelusions 43 Aeknowledgements 44 19 Manuscripts published, submitted 01' in preparation 20 Late Quaternary insolation forcing on total organic carbon and C37 alkenone variations in the Arabian Sea Dörte Budziak l , Ralph R. Schneiderl, Frauke Rostek2, Peter J. Müller l , Edouard Bard2, and Gerold Wefer l lFachbereich Geowissenschaften, Universität Bremen, Postfach 330 440, 28334 Bremen, Gennany 2Centre Europeen de Reserche et d'Enseignement en Geosciences de 1'Environment, Universite d'Aix-Marseille III et CNRS-UMR-6635, Europöle de l'Arbois, BP80, 13545 Aix-en-Provence Cedex 4, France
Rehabilitation in Older Adults Affected by Immobility Syndrome, Aided by Virtual Reality Technology: A Narrative Review

Individual mobility deficit in older adults induces a variety of medical conditions, diminishing their functional capacity in pursuing activities of daily living. In immobility syndrome patients, such conditions are prone further deterioration through a drastically reduced scope of physical activity, owing mostly to poor self-motivation and the monotonous character of conventional rehabilitation regimens. As evidenced by published research, virtual reality technology solutions in rehabilitation management actually add significantly to patients’ self-motivation, while promoting their active involvement in therapy through visual, auditory, and kinaesthetic stimuli. Effective rehabilitation training aided by virtual reality solutions helps patients acquire specific physical and cognitive skills to be subsequently emulated in the real-world environment. The extra added advantage lies in facilitating such training within patients’ own home environments, combined with online monitoring of their progress, when not personally supervised by a physiotherapist, which also boosts the overall cost effectiveness of the therapeutic management itself. This narrative review appears to be the very first one principally focused on critically comparing individual immobilisation with immobility syndrome, especially through the application of the Authors’ own substantial hands-on therapeutic experience in managing various rehabilitation schemes, specifically aided by diverse virtual reality technology solutions.
A Rare Presentation of Intrasellar Mucocele Post-transsphenoidal Resection of a Non-secreting Pituitary Macroadenoma

An enlarging sphenoid sinus mucocele can facilitate the growth of an intrasellar sinus mucocele. This subsequently leads to pituitary gland compression and endocrine abnormalities. We report the case of a 54-year-old man who underwent transsphenoidal resection of a non-secreting pituitary macroadenoma. Twenty years later he presented with headache, visual disturbances, erectile dysfunction, and poor libido and was diagnosed with a large sphenoid sinus mucocele that consequently extended into the sellar region. Based on the literature review, isolated intrasellar sinus mucocele post-transsphenoidal endoscopic surgery has been reported once. This is the first case of an intrasellar mucocele post-transsphenoidal resection to present with endocrine compromise on top of the compressive pituitary stalk symptoms.
METRICS AND SPECIAL KÄHLER GEOMETRY ON THE MODULI SPACES OF HIGGS BUNDLES AND HITCHIN SYSTEMS

The notions of Hitchin systems and Higgs bundles (also called Higgs pairs) were introduced by N. Hitchin in 1987. They rapidly formed a subject lying on the crossroads of representation theory, symplectic geometry and algebraic geometry. In this research area, the main objects that attract mathematicians’ attention are the moduli spaces of Higgs bundles Mn,d (the moduli space of Higgs bundles is a space parameterising the collection of all Higgs bundles). These moduli spaces have many good properties that make them interesting objects worthy of study. They are symplectic manifolds. For example, the moduli space of the Higgs bundles with rank one and degree zero is the cotangent bundle of the Jacobian variety of a Riemann surface. These moduli spaces are also equipped with Riemannian hyperkähler metrics ghk which cannot be written explicitly in general, but can be approximated by another metric, gs f , called the semi-flat metric. Roughly, ghk = gs f + {correction}. In fact, Gaiotto et al. conjectured what the ‘correction’ should be in 2013 [5]. To find the semi-flat metric of Mn,d, we first investigate the integrable system (Hitchin system) h :Mn,d → B, where the map h is known as the Hitchin map. The Lagrangian fibres of the Hitchin systems are Jacobian (or Prym) varieties of spectral curves of a given compact Riemann surface. The semi-flat metric ofMn,d is induced by a special Kähler metric on B through the Lagrangian fibration. In the thesis, we compute these metrics as explicitly as possible and give close approximations to them. In Chapter 1, we recall the basic notions of Hitchin systems [6–8]. In Chapters 2, 3 and 4, we give formulas for SLn(C)and GLn(C)-Hitchin systems. To do that, we treat the regular part of the Hitchin systems as complex torus bundles
Status, Testosterone, and Human Intellectual Performance Stereotype Threat as Status Concern

Results from two experiments suggest that stereotype-threat effects are special cases of a more general process involving the need to maintain or enhance status. We hypothesized that situations capable of confirming a performance stereotype might represent either a threat to status or an opportunity for enhancement of status, depending on the nature of the stereotype. The positive relationship between baseline tes- tosterone and status sensitivity led us to hypothesize that high testosterone levels in males and females would amplify existing performance expecta- tions when gender-based math-performance stereotypes were activated. In Study 1, high-testosterone females performed poorly on a math test when a negative performance stereotype was primed. In Study 2, high- testosterone males excelled on a math test when a positive performance stereotype was primed. The moderating effect of testosterone on perfor- mance suggests that a stereotype-relevant situation is capable of conferring either a loss or a gain of status on targets of the stereotype.
Anatomical identification of a corticocortical top-down recipient inhibitory circuitry by enhancer-restricted transsynaptic tracing

Despite the importance of postsynaptic inhibitory circuitry targeted by mid/long-range projections (e.g., top-down projections) in cognitive functions, its anatomical properties, such as laminar profile and neuron type, are poorly understood owing to the lack of efficient tracing methods. To this end, we developed a method that combines conventional adeno-associated virus (AAV)-mediated transsynaptic tracing with a distal-less homeobox (Dlx) enhancer-restricted expression system to label postsynaptic inhibitory neurons. We called this method “Dlx enhancer-restricted Interneuron-SpECific transsynaptic Tracing” (DISECT). We applied DISECT to a top-down corticocortical circuit from the secondary motor cortex (M2) to the primary somatosensory cortex (S1) in wild-type mice. First, we injected AAV1-Cre into the M2, which enabled Cre recombinase expression in M2-input recipient S1 neurons. Second, we injected AAV1-hDlx-flex-green fluorescent protein (GFP) into the S1 to transduce GFP into the postsynaptic inhibitory neurons in a Cre-dependent manner. We succeeded in exclusively labeling the recipient inhibitory neurons in the S1. Laminar profile analysis of the neurons labeled via DISECT indicated that the M2-input recipient inhibitory neurons were distributed in the superficial and deep layers of the S1. This laminar distribution was aligned with the laminar density of axons projecting from the M2. We further classified the labeled neuron types using immunohistochemistry and in situ hybridization. This post hoc classification revealed that the dominant top-down M2-input recipient neuron types were somatostatin-expressing neurons in the superficial layers and parvalbumin-expressing neurons in the deep layers. These results demonstrate that DISECT enables the investigation of multiple anatomical properties of the postsynaptic inhibitory circuitry.
The Marine Plankton of the Coastal Waters of Calicut with Observations on the Hydrological Conditions

The present paper is the outcome of regular plankton and hydrological investigations off West Hill, Calicut, for' the three years 1948-5l. There has been very little detailed work done on the plankton and hydrology of Indian coastal waters, especially along the West Coast of India except for the account of the seasonal fluctuations of the plankton of the Trivandrum Coast by Menon (1945) and notes on the plankton of the Malabar Coast by Hornell and Nayidu (1923) and of the Bombay Harbour by Bal and Pradhan (1945) and Gonzalves (1947).
ALA induces stomatal opening through regulation among PTPA, PP2AC, and SnRK2.6

5-Aminolevulinic acid (ALA), as a new natural plant growth regulator, has been proved to regulate protein phosphatase 2A (PP2A) activity to promote stomatal opening in apple (Malus domestica) leaves. However, the molecular mechanisms underlying remain unclear. Here, we cloned and transformed MdPTPA, MdPP2AC, and MdSnRK2.6 of apple into tobaccos (Nicotiana tabacum) and found that over-expression (OE)-MdPTPA or OE-MdPP2AC promoted stomatal aperture while OE-MdSnRK2.6 induced stomatal closure under normal or drought condition. The Ca2+ and H2O2 levels in the guard cells of OE-MdPTPA and OE-MdPP2AC was decreased but flavonols increased, and the results in OE-SnRK2.6 was contrary. Exogenous ALA stimulated PP2A activity but depressed SnRK2.6 activity in transgenic tobaccos, leading to less Ca2+, H2O2 and more flavonols in guard cells, and consequently stomatal opening. OE-MdPTPA improved stomatal opening and plant growth but impaired drought tolerance, while OE-MdSnRK2.6 improved drought tolerance but depressed the leaf P n. Only OE-MdPP2AC improved stomatal opening, leaf P n, plant growth, as well as drought tolerance. These suggest that the three genes involved in ALA-regulating stomatal movement have their respective unique biological functions. Yeast two-hybrid (Y2H) assays showed that MdPP2AC interacted with MdPTPA or MdSnRK2.6, respectively, but no interaction of MdPTPA with MdSnRK2.6 was found. Yeast three-hybrid (Y3H) assay showed that MdPTPA promoted the interactions between MdPP2AC and MdSnRK2.6. Therefore, we propose a regulatory module of PTPA-PP2AC-SnRK2.6 that may be involved in mediating the ALA-inducing stomatal aperture in green plants.
Effect of Spirulina on growth, immunity, gut bacterial load and histopathology of broiler birds

This study was carried out to evaluate the effects of Spirulina on growth, immunity, gut microbiome, and important organ histopathology in Vencobb broilers. 160 day-old chicks were randomly assigned to four diets. T0: basal diet, T1: basal diet + Spirulina (0.50% of basal diet), T2: basal diet + Spirulina (1.0% of basal diet), T3: basal diet + Spirulina (1.50% of basal diet). The experimental period was 35 days. Body weight change was measured at weekly intervals. Humoral immunity, cellular immunity, lymphoid organ mass, histopathology, intestinal bacterial load and intestinal morphology were measured on the 35thday of the experimental feeding period. Body weights were significantly higher in all treated birds than in control. Lymphatic organ weights, HI titers and CBH responses in the various treatment groups were significantly higher than those in the control group. The total bacteria (log10cfu/ml), Escherichia coli and Salmonella counts in the intestinal contents were significantly lower in the Spirulina treated group than in the control group, and the intestinal Lactobacillus count was higher in the treated birds than in the control group. The villi length and width of the treated birds were significantly greater than those of the control group. Histopathology studies have shown that Spirulina @ 1.5% of the basal diet have no detrimental effect on the bird’s liver and kidneys. It can be concluded that adding 1.50% Spirulina to the diet of Vencobb broilers improves growth, immunity and reduces gut microbial load.
A 16-year bicentric retrospective analysis of ovarian tissue cryopreservation in pediatric units: indications, results, and outcome

Background Cancer treatments of the last decades improve the survival rate of children and adolescents. However, chemo- and radiotherapy result in gonadal damage, leading to acute ovarian failure and sterility. The preservation of fertility is now an integral part of care of children requiring gonadotoxic treatments. Ovarian tissue cryopreservation (OTC) is an effective fertility preservation option that allows long-term storage of primordial follicles, subsequent transplantation, and restoration of endocrine function and fertility. The efficacy of this technique is well-demonstrated in adults but the data are scarce for pediatric patients. Currently, OTC represents the only possibility of preserving the potential fertility in prepubertal girls. Procedure This is a retrospective study of OTC practice of two French centers from January 2004 to May 2020. A total of 72 patients from pediatric units underwent cryopreservation of ovarian tissue before gonadotoxic therapy for malignant or non-malignant diseases. The ovarian cortex was cut into fragments and the number of follicles per square millimeter was evaluated histologically. The long-term follow-up includes survival rate and hormonal and fertility status. Results The mean age of patients at OTC was 9.3 years [0.2–17] and 29.2% were postpubertal; 51 had malignant diseases and 21 had non-malignant diseases. The most frequent diagnoses included acute leukemia, hemoglobinopathies, and neuroblastoma. Indication for OTC was stem cell transplantation for 81.9% (n = 59) of the patients. A third of each ovary was collected for 62.5% (n = 45) of the patients, a whole ovary for 33.3% (n = 24) of the patients, and a third of one ovary for 4.2% (n = 3) of the patients. An average of 17 fragments [5–35] per patient was cryoconserved. A correlation was found between the age of the patients and the number of fragments (p < 0.001). More fragments were obtained from partial bilateral harvesting than from whole ovary harvesting (p < 0.05). Histological analysis of ovarian tissue showed a median of 6.0 primordial follicles/mm2 [0.0–106.5] and no malignant cells were identified. A negative correlation was found between age and follicular density (p < 0.001). Median post-harvest follow-up was 92 months [1–188]. A total of 15 girls had died, 11 were still under treatment for their pathology, and 46 were in complete remission. Of all patients, 29 (40.2%) were subjected to a hormonal status evaluation and 26 were diagnosed with premature ovarian insufficiency (POI) (p < 0.001). One patient had undergone thawed ovarian tissue transplantation. Conclusion OTC should be proposed to all girls with high risk of developing POI following gonadotoxic therapies in order to give them the possibility of fertility and endocrine restoration.
Comparison of the Accuracy of a Mounting Fixture for Dental Implants for Implant Position Transfer and Open-Tray Implant Level Impression—An In Vitro Study

The accuracy for the implant position transfer of a mounting fixture and a standardized open-tray implant level impression was compared. Ten aluminum master models with four implant analogs placed in different angulations were fabricated. By performing an open-tray implant level impression stone casts were produced. The master models and stone casts were scanned (comparison group one) using a laboratory scanner. Deviations in the scan body surface were determined in the form of mean (absolute) point distances and (signed) surface distances. The same procedure was performed with a screwed transfer and by fixing the posts of the mounting fixture (comparison group two). The mounting device was applied to each master model and scanned in a fixed and detached state (comparison group three). In a point comparison, the open-tray implant level impression showed mean deviations of 43.6 µm and a mounting fixture of 44.6 µm with no significant differences (p < 0.05). There were significant differences between groups two and three. The angulation of the implants had no effect on the accuracy. In a surface comparison, the open-tray implant level impression showed mean deviations of 36.0 µm and a mounting fixture of 2.0 µm (p > 0.05). Within the limits of this study, the mounting fixture transferred the implant position with the same accuracy as the open-tray implant level impression with respect to point deviations.
Effects of the neonatal intensive care environment on circadian health and development of preterm infants

The circadian system in mammals ensures adaptation to the light-dark cycle on Earth and imposes 24-h rhythmicity on metabolic, physiological and behavioral processes. The central circadian pacemaker is located in the brain and is entrained by environmental signals called Zeitgebers. From here, neural, humoral and systemic signals drive rhythms in peripheral clocks in nearly every mammalian tissue. During pregnancy, disruption of the complex interplay between the mother’s rhythmic signals and the fetal developing circadian system can lead to long-term health consequences in the offspring. When an infant is born very preterm, it loses the temporal signals received from the mother prematurely and becomes totally dependent on 24/7 care in the Neonatal Intensive Care Unit (NICU), where day/night rhythmicity is usually blurred. In this literature review, we provide an overview of the fetal and neonatal development of the circadian system, and short-term consequences of disruption of this process as occurs in the NICU environment. Moreover, we provide a theoretical and molecular framework of how this disruption could lead to later-life disease. Finally, we discuss studies that aim to improve health outcomes after preterm birth by studying the effects of enhancing rhythmicity in light and noise exposure.