Miracle-dz/UniFAR-FTUs huggingface dataset:
Brand Equity, Tourist Satisfaction and Travel Intentions in a UNESCO Creative City of Gastronomy: A Case Study of Yangzhou, China

Food is an indispensable part of destination tourism resources and attractions, playing a vital role in the marketing and promotion of the destination. Food can also be viewed as an important brand that the destination can develop. Yangzhou has been listed as a UNESCO Creative City of Gastronomy since 2019, and the government aims to enhance the food brand for the city. This study attempts to assess the impact of a destination’s food brand equity on tourist satisfaction and travel intentions, and to evaluate the potential of developing food tourism. Questionnaires were conducted with 481 tourists, followed by semi-structured interviews with 29 tourists. A structural equation modelling analysis addressed the positive relationships among destination food brand equity, tourist satisfaction and travel intentions. A qualitative analysis contributes to further clarifying the relationships of the model. Implications for theory, research and practice are discussed.
Cosmology from the bispectrum

With a suite of current and up-coming experiments set to provide us the with exquisite measurements of the sky in a wide range of frequencies, we are posed with the problem of how to maximally utilise these data sets. Historically two-point function measurements have been the tool of choice, and they have been highly effective. However, two point functions are unable to extract all the available information, particularly on the small, non-linear scales. With the goal of providing complimentary measurements to the power spectrum, we use the bispectrum to explore a range of physical processes. In the first half of this thesis, we discuss two applications of the bispectrum to probe large scale structure. Firstly we measure the bispectrum from secondary anisotropies of the cosmic microwave background using data from the Atacama Cosmology telescope and the Planck Satellite. Secondly we use a suite of simulations to explore the bispectrum of weak lensing shear maps. Using these simulations we explore how bispectrum measurements can be used to enhance our ability to measure cosmological parameters, including the sum of the masses of the neutrinos. We find that, for an experiment like the Large Synoptic Sky Survey, including information from the bispectrum will enhance parameter constraints by 30%. In the second half of this thesis, we discuss two aspects regarding primordial gravitational waves. First we discuss how measurements of the bispectrum can be used to probe primordial non-Gaussianity between tensor and scalar fields and present our preliminary constraints on interactions between these fields. Secondly we discuss how bispectrum measurements of galactic foregrounds, including polarised dust and synchrotron emission, have the potential to help discriminate between the desired signal from primordial gravity waves and galactic contaminants.
THM-OTFT: A Complete Physics-Based Verilog-A Compact Model for Short-Channel Organic Thin-Film Transistors

This paper presents a compact model for organic thin-film transistors fabricated in the staggered or coplanar device architecture which includes short-channel effects related to the potential barrier in the channel region, which manifest themselves as threshold voltage roll-off, drain-induced barrier lowering, and subthreshold swing degradation. Furthermore, the effect of non-linear injection due to a work-function mismatch between the source/drain contacts and the semiconductor is considered. The model includes a charge-based capacitance model considering overlap and fringing regions in short-channel multi-finger layout structures. Extensions include a model for drain-current variability, low-frequency noise and non-quasistatic effects. The introduction of physically meaningful fitting parameters provides a high degree of flexibility to the model. The equation package is verified using the results of measurements performed on transistors fabricated on flexible substrates and is available in Verilog-A for an efficient circuit simulation on different design platforms.
Genomic and biological characterization of Pigeon Paramyxovirus Type-1 isolated from Indian pigeons: First report on the six nucleotide insertion in the non-coding region of nucleoprotein gene

Genotypic analysis of Pigeon Paramyxovirus Type-1 (PPMV-1) virus, in corroboration with pathotyping, underpins the knowledge on the occurrence of PPMV-1 mediated Newcastle disease in poultry. In the present study, two PPMV-1 isolates, namely D167 and D168, obtained from feral pigeons of India in the year 2014 were analysed for their genotypic and pathotypic characteristics. Phylogenetic analysis of Fusion (F) gene grouped D167 and D168 under sub-genotypes VI.2.2.2. and VI.2. 1.1. 2.2. respectively. The separate positioning of these isolates within genotype VI is corroborated with the variation in restriction enzyme sites analysed through virtual restriction mapping. Analysis of FPCS region showed that both D167 and D168 possessed 112RRQKRF117 amino-acid pattern. Intra-cerebral pathogenicity index (ICPI) of D167 and D168 was 1.57 and 1.3, and mean death time (MDT) was 48 and 70 hrs respectively, designating D168 as a mesogenic pathotype, and D167 as a velogenic pathotype. Histopathological analysis of proventriculus, intestine, lungs and spleen of chickens infected with D167 and D168 isolates through intramuscular (I/M), subcutaneous (S/C) and oculo-nasal/oral (O/N) routes of inoculation showed similar severity of tissue damage. This study shows that PPMV-1 isolates belonging to two different sub-genotypes without a common ancestor, can occur together in a particular geographical region. It also shows that PPMV-1 gains virulence in chickens, which needs to be addressed in order to avoid emergence of PPMV-1 as new velogenic variant causing Newcastle disease in chickens.
Professional Development of Christian Education Teachers Based on Scientific Writing Products to Improve Learning Quality and Career Improvement Assisted Module

Research and publication of scientific papers become the main problems in the professional development of teachers. This aims of this research is to develop sustainable professional teacher through research product-based training models and the publication of scientific papers. It analyses the need for a training management model that can increase the professionalism of Christian education subject teachers who are civil servants to produce scientific papers. This research is using qualitative methods with a Research and Development model approach. The data analysis technique used the Mann-Whitney U test technique. Sources of training data are primary data and secondary data. Primary data was obtained from the interview process of all training participants, and secondary data was obtained based on the analysis of the training module directory, training directory and examples of training product administrators. The results showed the validity level of the training module was in a good category (72%), the results of scientific papers using the IHT module are higher than before using the training module; the product of scientific papers produced by the teacher has met the requirements for promotion; the resulting training product in the form of scientific papers is useful for improving school performance and teacher motivation for higher careers.
Wake-Wake Interactions and its Potential for Clocking in a Transonic High Pressure Turbine

Two-dimensional unsteady Navier-Stokes calculations of a transonic single stage high pressure turbine were carried out with emphasis on the flow field behind the rotor. Detailed validation of the numerical procedure with experimental data showed excellent agreement in both time-averaged and time-resolved flow quantities. The numerical time-step as well as the grid resolution allowed the prediction of the Karman vortex streets of both stator and rotor. Therefore the influence of the vorticity shed from the stator on the vortex street of the rotor is detectable. It was found that certain vortices in the rotor wake are enhanced while others are diminished by passing stator wake segments. A schematic of this process is presented. In the relative frame of reference the rotor is operating in a transonic flow field with shocks at the suction side trailing edge. These shocks interact with both rotor and stator wakes. It was found that a shock-modulation occurs in time and space due to the stator wake passing. In the absolute frame of reference behind the rotor a 50% variation in shock strength is observed according to the circumferential or clocking position. Furthermore a substantial weakening of the rotor suction side trailing edge shock in flow direction is detected in an unsteady flow simulation when compared to a steady state calculation which is caused by convection of upstream stator wake segments. The physics of the mentioned unsteady phenomena as well as their influence on design are discussed.Copyright © 2001 by ASME
Sex Differences in Immune Cell Infiltration and Hematuria in SCI-Induced Hemorrhagic Cystitis

Rats manifest a condition called hemorrhagic cystitis after spinal cord injury (SCI). The mechanism of this condition is unknown, but it is more severe in male rats than in female rats. We assessed the role of sex regarding hemorrhagic cystitis and pathological chronic changes in the bladder. We analyzed the urine of male and female Sprague-Dawley and Fischer 344 rats after experimental spinal cord contusion, including unstained microscopic inspections of the urine, differential white blood cell counts colored by the Wright stain, and total leukocyte counts using fluorescent nuclear stains. We examined bladder histological changes in acute and chronic phases of SCI, using principal component analysis (PCA) and clustered heatmaps of Pearson correlation coefficients to interpret how measured variables correlated with each other. Male rats showed a distinct pattern of macroscopic hematuria after spinal cord injury. They had higher numbers of red blood cells with significantly more leukocytes and neutrophils than female rats, particularly hypersegmented neutrophils. The histological examination of the bladders revealed a distinct line of apoptotic umbrella cells and disrupted bladder vessels early after SCI and progressive pathological changes in multiple bladder layers in the chronic phase. Multivariate analyses indicated immune cell infiltration in the bladder, especially hypersegmented neutrophils, that correlated with red blood cell counts in male rats. Our study highlights a hitherto unreported sex difference of hematuria and pathological changes in males and females’ bladders after SCI, suggesting an important role of immune cell infiltration, especially neutrophils, in SCI-induced hemorrhagic cystitis.
The Role and Mechanism of MicroRNA 21 in Osteogenesis: An Update

MicroRNAs are short, single-stranded ribonucleic acids expressed endogenously in the body to regulate gene expression at the post-translational level, with exogenous microRNA offering an attractive approach to therapy. Among the myriad microRNA candidates involved in controlling bone homeostasis and remodeling, microRNA 21 (miR21) is the most abundant. This paper discusses the studies conducted on the role and mechanism of human miR21 (hsa-miR21) in the regulation of bones and the various pathways mediated by miR21, and explores the feasibility of employing exogenous miR21 as a strategy for promoting osteogenesis. From the literature review, it was clear that miR21 plays a dual role in bone metabolism by regulating both bone formation and bone resorption. There is substantial evidence to date from both in vitro and in vivo studies that exogenous miR21 can successfully accelerate new bone synthesis in the context of bone loss due to injury or osteoporosis. This supports the exploration of applications of exogenous miR21 in bone regenerative therapy in the future.
Coastal outflow currents into a buoyant layer of arbitrary depth

The long-wave, reduced-gravity, shallow-water equations (the semi-geostrophic equations) are used to study the outflow of a river into the ocean. While previous models have studied dynamics driven by gradients in density, the focus here is on the effects of potential vorticity anomaly (PVa). The river water is taken to have the same density as a finite-depth upper layer of oceanic fluid, but the two fluids have different, uniform, potential vorticities. Under these assumptions, the governing equations reduce to two first-order, nonlinear partial differential equations which are integrated numerically for a prescribed efflux of river water and PVa. Results are found to depend strongly on the sign of the PVa, with all fluid turning downstream (in the direction of Kelvin-wave propagation) when the river water has positive PVa and anticyclonic flow upstream of the river mouth when the PVa is negative. In all cases, a nonlinear Kelvin wave propagates at finite speed ahead of the river water. Away from the river mouth, the uniformity of one set of Riemann invariants allows for similarity solutions that describe the shape of the outflow, as well as a theory that predicts properties of the Kelvin wave. A range of behaviours is observed, including flows that develop shocks and flows that continue to expand offshore. The qualitative behaviour of the outflow is strongly correlated with the value of a single dimensionless parameter that expresses the ratio of the speed of the flow driven by the Kelvin wave to that driven by image vorticity.
Current Characteristics Analysis and Fault Injection of an Early Weak Fault in Broken Rotor Bar of Traction Motor

Aiming at the destructive and irreversible problems of the broken rotor bar fault of the traction motor, the current characteristics of the early weak fault of the single bar are analyzed, and the broken rotor bar fault simulation injection is realized on the experimental platform. Firstly, a damage factor from the change rule of the metal resistance value of a rotor bar is defined. By means of such a damage factor, the relationship between the severity of the fracture of a single rotor bar and the phase resistance of the traction motor was obtained. Through the superposition principle, the traction motor in the fault of the rotor bar was regarded as a normal motor in which the reverse current source was superimposed on the fault rotor bar. The characteristic values of the stator current fault component were obtained when the single bar had broken. Finally, the relationship between the fault characteristics component of the stator current and the fracture severity of the single rotor bar was established. On this basis, on hardware-in-the-loop fault injection benchmark of the traction drive control system based on dSPACE, the gradual injection of early weak faults in the early broken rotor bar was carried out and the results were analyzed. The experimental data demonstrated the correctness of the current characteristics analysis and fault injection.
Partial ulnar ostectomy, stereotactic body radiation therapy, and palliative radiation therapy as local limb sparing treatment modalities for ulnar tumors in dogs

Background Information on dogs that undergo limb preserving local treatment for ulnar tumors is currently limited. Objective To describe the clinical characteristics and outcomes in dogs that underwent partial ulnectomy or radiation therapy (RT) for ulnar bone tumors, and to evaluate potential risk factors for outcomes as well as pre-treatment factors for association with treatment modality selected. Animals Forty client-owned dogs that underwent partial ulnectomy or RT for an ulnar tumor from July 2006 to July 2021. Methods The medical records database from a single institution were retrospectively reviewed, and data were recorded and analyzed. Results Radiation therapy was performed in 24 dogs, with 12 stereotactic body RT (SBRT) and 12 palliative RT (PRT) plans, and partial ulnectomy was performed in 16 dogs. Biomechanical complications occurred in 6/12 (50%) dogs that underwent SBRT, 6/12 (50%) dogs that underwent PRT, and 3/16 (18.8%) dogs that underwent ulnectomy. The majority of dogs had a good functional outcome following partial ulnectomy, and no dogs required surgical stabilization of the carpus even with lateral styloid process excision. Pathologic fracture occurred in 4/12 (33.3%) dogs following SBRT and 5/12 (41.7%) dogs following PRT. Local progression or recurrence was documented in 5/12 (41.7%) dogs that underwent SBRT, 2/12 (16.7%) dogs that underwent PRT, and 2/16 (12.5%) dogs that underwent ulnectomy. The overall median survival time was 198 days, and factors that were significantly associated with improved survival time included adjuvant chemotherapy administration and partial ulnectomy as local treatment method for dogs that received chemotherapy. Clinical relevance Both RT and ulnectomy were effective and well tolerated local treatment modalities for dogs with ulnar tumors.
Association of vasoactive intestinal peptide receptor 1 gene polymorphism with layer economic traits in Rhode Island Red chicken

The research work was conducted to determine allelic polymorphism of vasoactive intestinal peptide receptor-1 (VIPR-1) gene and its association with layer traits in Rhode Island Red (RIR) chicken. Blood samples were collected from pullets (n=111) belonging to five hatches. Data on body weight at 20 weeks of age (BW20) and layer economic traits, viz. age at sexual maturity (ASM), egg weight at 28 (EW28) and 40 weeks (EW40) of age, and egg production up to 40 weeks of age (EP40)) were recorded. Genomic DNA was isolated by phenol chloroform extraction method. Samples were amplified for product sizes of 364, 434 and 486 bp of VIPR-1 gene. Amplified regions were digested by TaiI, HhaI and TaqI restriction enzymes. Digested fragments of TaiI and HhaI revealed monomorphism, whereas TaqI showed polymorphism. Allelic frequencies for polymorphic locus were 0.98 (A) and 0.02 (B) and genotypic frequencies for AA and AB were 0.96 and 0.04, respectively. The BW20 and layer traits (ASM, EW28, EW40 and EP40) were analysed by least-squares analysis of variance taking sire as random and hatch as fixed effect. Average ASM and egg production up to 40 weeks of age were 135.19±1.15 days and 124.55±1.94 eggs, respectively. Least-square analysis of variance had revealed significant effect of hatch on ASM, EW28 and EP40. However, effect of TaqI-RFLP genotypes was non-significant on layer traits. Further investigations on a larger sample basis are suggested to confirm effect of this mutation on layer traits as molecular marker in RIR chicken.
Influence of Homogenization on Phase Transformations during Isothermal Aging of Inconel 718 Superalloys Fabricated by Additive Manufacturing and Suction Casting

The attainment of the desired strength of the Inconel 718 superalloy heavily relies on the isothermal aging process, which plays a critical role in achieving the anticipated hardening effect. Surprisingly, there remains a dearth of dedicated studies investigating the influence of homogenization on phase transformations during the isothermal aging process, leaving a gap in the knowledge required to guide the design of post-heat treatment strategies. Addressing this gap, our work investigates the impact of homogenization time on phase transformations during isothermal aging at 730 °C in Inconel 718 alloys produced via additive manufacturing (AM) and suction casting (SC) methods. Intriguingly, we observe contrasting behaviors in the particle size of γ″ and γ′ in aged samples, depending on the homogenization time and the alloy processing method. Specifically, in AM alloys, extended homogenization time leads to an increase in the particle size of γ″ and γ′, whereas the opposite trend is observed in SC alloys. Furthermore, despite undergoing the same heat treatment, the AM alloys exhibit smaller particle sizes but higher precipitate number densities compared to the SC alloys, resulting in superior hardness. Notably, pronounced grain refinement during aging is evident in 1 h homogenized SC samples under 1180 °C, warranting further investigations into the underlying mechanisms. This study elucidates the crucial role of homogenization in attaining the desired microstructure following subsequent aging processes. Moreover, it offers novel insights for developing post-heat treatment strategies for superalloys.
Glioblastoma-on-a-chip construction and therapeutic applications

Glioblastoma (GBM) is the most malignant type of primary intracranial tumor with a median overall survival of only 14 months, a very poor prognosis and a recurrence rate of 90%. It is difficult to reflect the complex structure and function of the GBM microenvironment in vivo using traditional in vitro models. GBM-on-a-chip platforms can integrate biological or chemical functional units of a tumor into a chip, mimicking in vivo functions of GBM cells. This technology has shown great potential for applications in personalized precision medicine and GBM immunotherapy. In recent years, there have been efforts to construct GBM-on-a-chip models based on microfluidics and bioprinting. A number of research teams have begun to use GBM-on-a-chip models for the investigation of GBM progression mechanisms, drug candidates, and therapeutic approaches. This review first briefly discusses the use of microfluidics and bioprinting technologies for GBM-on-a-chip construction. Second, we classify non-surgical treatments for GBM in pre-clinical research into three categories (chemotherapy, immunotherapy and other therapies) and focus on the use of GBM-on-a-chip in research for each category. Last, we demonstrate that organ-on-a-chip technology in therapeutic field is still in its initial stage and provide future perspectives for research directions in the field.
Ultrafast spectral dynamics of dual-color-soliton intracavity collision in a mode-locked fiber laser

The single-shot spectral dynamics of dual-color-soliton collisions inside a mode-locked laser is experimentally and numerically investigated. By using the all-optically dispersive Fourier transform, we spectrally unveil the collision-induced soliton self-reshaping process, which features dynamic spectral fringes over the soliton main lobe, and the rebuilding of Kelly sidebands with wavelength drifting. Meanwhile, the numerical simulations validate the experimental observation and provide additional insights into the physical mechanism of the collision-induced spectral dynamics from the temporal domain perspective. It is verified that the dynamic interference between the soliton and the dispersive waves is responsible for the observed collision-induced spectral evolution. These dynamic phenomena not only demonstrate the role of dispersive waves in the sophisticated soliton interaction inside the laser cavity, but also facilitate a deeper understanding of the soliton's inherent stability.
Mass Spectra of Heavy and Light Mesons Using Asymptotic Iteration Method

The non-relativistic radial Schrödinger equation is analytically solved using asymptotic iteration method within the framework of a general interaction potential whose special cases are the Cornell and Cornell plus harmonic potentials. The energy eigenvalues expression is derived in three dimensional space, which is further used to calculate the mass spectra of c̄c, b̄b, b̄c, cs̄, bs̄ and b̄q mesons. The obtained results of this work are in good agreement with experimental and other relativistic results and also improved in comparison with other non-relativistic recent studies.