Miracle-dz/UniFAR-FTUs huggingface dataset:
Drug therapy problems and treatment satisfaction among ambulatory patients with epilepsy in a specialized hospital in Ethiopia

Objective Epilepsy management especially in developing country is challenging. Seizures recurrence can be caused by both drug and non-drug related problems such as inadequate antiepileptic regimens, adverse drug reaction and poor adherence. Patient treatment satisfaction also affects the treatment out comes by improving medication adherence. This study aimed to assess drug therapy problems (DTPs) and treatment satisfaction among ambulatory epileptic patients at Tikur Anbessa Specialized Hospital. Methods A prospective cross-sectional study was conducted on 291 epileptic patients. Data was collected through patient interview and medical charts review. DTPs were identified based on the standard treatment guidelines and Micromedex® was used as drug interaction checker. Cipolle DTPs classification was used to classify the DTPs and Treatment Satisfaction with Medicine Questionnaire (SATMED-Q) was used to assess treatment satisfaction. Binary logistic regressions were utilized to identify the associated factors. Results Phenobarbital 195 (67%) and phenytoin 97 (33.3%) were the most frequently prescribed antiepileptic medications as monotherapy or combination therapy. Only 54 (18.6%) of the study participants had controlled seizure. DTP was found in 205(70.4%) of the study participants. From 352 DTPs identified, adverse drug reaction 146 (41.5%) was the leading DTPs followed by ineffective drugs 98 (27.8%) drug interaction 45 (12.8%) and inappropriate dose 42(11.9%). Headache, depression and epigastric pain were frequently reported adverse drug reaction. Among the study participants 167 (57.3%) were adherent to their medications. The number of medications taken by the patients had significant association with occurrence of DTPs, whereas source of medication and seizure free periods were found to have significant association with poor adherence. The global patient satisfaction was (67.4%) and lower satisfaction rate was found with regard to impact on daily activities (62.0%), treatment effectiveness (64.7%) and medical care (65.9%). Conclusion Prevalence of DTPs among ambulatory epileptic patients was high and about half of the patients were nona-dherent for their medication. The overall treatment satisfaction of the patients was suboptimal.
Mining query logs induced graphs

The human interaction through the web generates both implicit and explicit knowledge. An example of an implicit contribution is searching, as people contribute with their knowledge by clicking on retrieved documents. When this information is available, an important and interesting challenge is to extract relations from query logs, and, in particular, semantic relations between queries and their terms. In this paper we present and discuss results on mining large query log induced graphs, namely click induced graphs, and how they contribute to query classification and to understand user intent and interest. Our approach consists on efficiently obtaining a hierarchical clustering for such graphs, which provide a hierarchical query folksonomy. We compare it against conventional taxonomies, namely the ODP categorization. Results obtained with real data show that the hierarchical clustering and the inferred query folksonomy provide interesting insights both on semantic relations among queries and on web users intent, being quite different from standard taxonomies.
Be Wary of Acupuncture, Qigong, and "Chinese Medicine"

"Chinese medicine," often called "Oriental medicine" or "traditional Chinese medicine (TCM)," encompasses a vast array of folk medical practices based on mysticism. It holds that the body's vital energy (chi or qi) circulates through channels, called meridians, that have branches connected to bodily organs and functions. Illness is attributed to imbalance or interruption of chi. Ancient practices such as acupuncture, Qigong, and the use of various herbs are claimed to restore balance.
Therapy-related myelodysplastic syndrome and acute myeloid leukemia after conventional therapy or autologous stem cell transplantation for non- Hodgkin’s lymphoma: a systematic review

Background: In patients with non-Hodgkin ́s lymphoma (NHL), an increase in longterm sequelae of cytotoxic therapies is being observed. Among those, therapyrelated myelodysplastic syndrome (t-MDS) and acute myeloid leukemia (t-AML) are among the most severe ones. However, data on incidence of t-MDS/t-AML following NHL therapies are conflicting. The aim of this review is to systematically evaluate the incidence of t-MDS/t-AML following conventional treatment and high-dose therapy with autologous stem cell transplantation in patients with NHL. Methods: To pursue this goal, a systematic review was performed. We screened the databases MEDLINE, EMBASE and Cochrane Library as well as congress proceedings and reference lists, to identify original articles, published in English between 1970 and 2008, on t-MDS/t-AML after NHL. Of 4040 potentially appropriate articles, 35 fulfilled our strict inclusion criteria, reporting on a total of 93094 patients with NHL. Results: Thirty-one original articles reported on cohort studies, 4 on randomized controlled trials. In 16/35 articles the primary endpoint was evaluation of t-MDS/tAML. “Crude incidence” was the most frequent measure of incidence, “actuarial incidence” and “cumulative incidence” were used occasionally. A total of 492 cases of t-MDS/t-AML were reported. In the group of conventionally treated patients, the crude incidence was between 0 and 8.2%, in the group with high-dose therapy and ASCT, between 0 and 13.6%. Due to missing data, subgroup analyses were not possible. Conclusion: The results of this systematic review show a higher incidence of tMDS/t-AML after high-dose therapy and ASCT for patients with NHL as compared to conventional treatment. This indicates a role for toxicity in the pathogenesis of tMDS/t-AML.
Response of two Wheat Cultivars to Foliar Fertilizer in Newly Cultivated Land

Two field experiments were carried out at Wadi El-Rayan, Fayoum governorate, Egypt, 2012 / 2013 and 2013 / 2014 seasons to study the effect of foliar spraying with Nitrophoska fertilizer on growth, yield, yield components and chemical composition in two wheat cultivars to improve wheat productivity. The results could be summarized as follows: Misr-2 cultivar surpassed significantly Baniswef-4 cultivar in all growth characters under study in all growth stages in both seasons such as plant height (cm), number of leaves/plant, number of tillers/plant, total dry weight (g), flag leaf area (cm) at 70, 100 and 130 days from sowing, also, number of spikes/m and weight of spikes (g/m) at 100 and 130 days after sowing. Significant variation were recorded between the tested foliar spraying treatments for growth characters at three growth stages in both seasons. The effective treatments for plant height, number of leaves and tillers/plant, total dry weight and flag leaf area / plant at 70, 100 and 130 days after sowing and number of spikes/m and weight of spikes/m at 100 and 130 days after sowing were obtained by spraying with 250cm/100 L. The interaction between wheat cultivars and foliar spraying with Nitrophoska fertilizer was significant increased in growth characters at all growth stages in both seasons. The highest values of all growth characters were obtained by using Misr-2 cultivar with 250cm/100L Nitrophoska fertilizer. Misr-2 cultivar gave higher plant height, number of spikes/m, grain and straw yields/m, weight of spikes/m,grain index, grain and straw yields (ton/fed.) and biological yield than Baniswef-4 cultivar in both seasons. Also, Misr-2 cultivar significantly surpassed Baniswef-4 cultivar for protein and carbohydrate percentage. While Baniswef-4 cultivar gave higher harvest index and productivity score than Misr-2 cultivar in both seasons. Spraying Nitrophoska fertilizer at rate of 250cm/100 L resulted in a significant increment in yield, yield component and chemical composition of wheat grain in both seasons. Significant variation between the tested rate of fertilizer treatments for all yield characters in both seasons. The effective treatment for all characters under study, except harvest index and productivity score was 250cm/100 L, while spraying with 200 cm/100 L gave the highest values of harvest index and productivity score. The effective treatments for number of spikes/m, grain yield g/m, grain index (g), biological yield g/m, grain yield ton/fed. , straw yield ton/fed. , biological yield ton/fed. , protein percentage and carbohydrate percentage were obtained from Misr-2 cultivar, with 250 cm/100 L. The differences between the two cultivars with 250 cm/ 100 L were not significant in plant height, weight of spikes/m and straw yield g/m. The highest values of harvest index and productivity score were obtained from Baniswef-4 cultivar with 250 cm/100 L Nitrophoska fertilizer in both seasons.
The Use of CSR Disclosure to Determine the Legitimacy of Halal Certificate

This study aims to show the legitimizing effect of Halal certificate by investigating its role of moderating variable towards the influence of firm characteristics on the level of CSR disclosure. In this research, CSR disclosure is classified into sourcing, environmental, and social disclosures. Year-ending 2011 Annual report disclosures of 43 food processing companies listed in Bursa Malaysia are analyzed. The sourcing, environmental, and social disclosures components of the GRI Sustainability Reporting Guidelines and Food Processing Sector Supplement (FPSS) which is intended for a specific food processing industry are used as the benchmark disclosure index checklist. Based on statistical analysis, the first hypothesis is partially found such as firm size positively influences the level of environmental and social disclosures; firm age positively influences the level of social disclosures; and leverage positively influences the level of sourcing, environmental, and social disclosures. The second hypothesis is partially found such as the degree of the influence of leverage on the level of environmental and social disclosures is decreasing within Halal certified companies. The main implication of the findings is that Halal certificate may increase the legitimacy of food processing companies with higher debt as well as reduce the perceived society’s pressures in terms of the impacts on the environment and society, but not in the case of the integrity of Halal food supply chain. This study reveals that the misuse of Halal logo has extensively damaged the reputation of Halal food products as safe, hygienist, high quality, as well as not contaminated with najis things. The amendments of the Trade Description Act 2011 that better protect the rights of consumers in Halal food products allow Halal certificate to increase its reputation.
Perceived Recurrence Risk and Health Behavior Change among Breast Cancer Survivors

Fear of recurrence is a primary concern for breast cancer survivors. While behavior changes may reduce recurrence risk, how perceived recurrence risk affects behavior change is unknown. We assessed perceived recurrence risk (local and distant) and change in nutrition, physical activity, and weight following diagnosis by questionnaire in a population of 267 breast cancer survivors. We used multinomial logistic regression to evaluate associations between perceived recurrence risk and health behavior change. The average participant was age 60 at diagnosis and had Stage I cancer (47.2%). Local or distant recurrence risk was perceived to be >30% by 20.2% and 30.3% of the population, respectively. Women most frequently reported increased physical activity (33.7%), improved nutrition (43.5%), and weight gain (33.0%). Higher local and distant perceived recurrence risk was associated with positive change in physical activity (OR 1.9, p=0.10; OR 1.7, p=0.12, respectively) and nutrition (OR 4.0, p<0.01; OR 2.0, p=0.05), while weight change was unrelated to perceived recurrence risk. Understanding women’s perceived recurrence risk may be useful in counseling them regarding behavior change following breast cancer.
Identification of Helicobacter Pylori in the Gallbladder of Egyptian Patients with Chronic Calculous Cholecystitis

The relationship between the H. pylori infection and cholelithiaisis still remains controversial. Some authors reported strong positive correlation while, others indicated totally negative results. Most of the studies carried out so far were mainly molecular and histopathological studies and failed to establish association between the colonization of H. pylori. in the biliary tract and stone diseases. On these bases the present study was carried out to investigate the presence of H. pylori in the gallbladder (GB) tissues, bile samples and gallstones of Egyptian patients with chronic calculous cholecystitis by microbiological and molecular methods, also, we tried to postulate on the probable etiological association of H. pylori with the disease. Our data showed that H. pylori was detected in 11.7% of GB mucosa and 12% of bile samples by microscopic examination and was successfully isolated from 11.7% and 10% of gallbladder tissues and bile respectively. Moreover, H. pylori DNA was detected by RT-PCR in 28.3%, 26% and 3.3% of gallbladder tissues, bile and stones respectively. Our results support a cause-and-effect association between H. pylori infection of the gallbladder and cholelithiaisis.
Fixed-effects estimation of the linear discrete-time hazard model: An adjusted first-differences estimator

This paper shows that popular linear fixed-effects panel-data estimators (first-differences, within-transformation) are biased and inconsistent when applied in a discrete-time hazard setting, that is, one with the outcome variable being a binary dummy indicating an absorbing state, even if the data generating process is fully consistent with the linear discrete-time hazard model. Besides conventional survival bias, these estimators suffer from another source of - potentially severe - bias that originates from the data transformation itself and is present even in the absence of any unobserved heterogeneity. We suggest an alternative, computationally very simple, adjusted first-differences estimator that cures the data-transformation driven bias of the classical estimators. The theoretical line of argument is supported by evidence from Monte Carlo simulations and is illustrated by an empirical application.
Introduction of OMP (One Minute Preceptor) As a Teaching Tool for Post Graduates in the Department of Obstetrics and Gynecology

One Minute Preceptor model of teaching is not being implemented in the PG teaching in the department of Obstetrics and Gynecology at Indira Gandhi Government Medical College, Nagpur so study was planned to find out the feasibility of introduction of OMP as post graduate teaching tool. The objectives of the study were – 1. To sensitize the faculty of department of Obstetrics and Gynecology about OMP. 2. To assess the feasibility of introduction OMP as postgraduate teaching tool in the department of Obstetrics and Gynecology. Validated Pretest and Post Test Questionnaire and role play were developed for demonstration of OMP module to suit the problem in department of Obstetrics and Gynecology. The total number of participants in the study was 26 in number. There were 14 teachers and12 Post Graduate students included in the study. Bedside teaching, discussions and seminars in the class were considered to be common group teaching activities by the participants while teaching during operative procedures, case discussions and ward rounds were noted to be one to one teaching activities. In Pretest, it is seen that 9 teachers (64.3%) did not have any opinion about OMP on Likert’s scale. In Post Test, it is seen that 13 out of 14 teachers liked or strongly liked OMP while only one teacher does not have any opinion on Likert’s scale. The results of Post Test of the teachers and PGs shows that OMP can be implemented endorsing all the advantages of OMP for improving overall teaching effectiveness. Key Words: OMP, postgraduates, teaching effectiveness
Mathematical models to predict growth, fillet traits, and composition of wild traíra, Hoplias malabaricus

ABSTRACT This study aimed to determine the length-weight relationship and mathematical models to predict dressed and fillet weight and yield and fillet composition of wild traira, Hoplias malabaricus (Bloch, 1794). A total of 80 marketable-sized fish from 292.28 to 2879.57 g and 32.06 to 61.19 cm were used. The length:weight ratio was estimated using the equation: , in which W is body weight (g) and L is length (cm). The models of dressed and fillet weight and yield and body [. ]
A 3V, 0.35pm CMOS Bluetooth Receiver IC

This paper presents a monolithic low-IF' Bluetooth receiver. The highlights of the receiver include a low-power active complex filter with a non-conventional tuning scheme and a high performance mixed-mode GFSK demodulator. The chip was fabricated on a 6.25 mm' die using TSMC 0.35pm standard CMOS process. -82 dBm sensitivity at le3 BER, -10 dBm IIP3 and 15 dB noise figure were achieved in the measurements.
THE BUILDING ENERGY SIMULATION TEST FOR EXISTING HOMES (BESTEST-EX) METHODOLOGY

The authors developed a method for testing the reliability of models that predict retrofit energy savings, including their associated calibration methods. The test suite applies the new Building Energy Simulation Test for Existing Homes (BESTEST-EX) Methodology, developed by the National Renewable Energy Laboratory in consultation with home energy retrofit industry software developers. BESTEST-EX includes building physics test cases with fully known inputs, and calibrated energy savings test cases with specified base-case monthly utility billing data and uncertainty ranges for selected inputs. The test cases apply a variety of retrofit scenarios in a heating and a cooling climate.
Role of Computer Assisted Nuclear Morphometric Analysis in Grading of Infiltrating Ductal Carcinoma of Breast (Nos Type) and Correlation with Established Prognostic Markers

Background: Grading of Infiltrating Duct Carcinoma (IDC) of the breast forms one of the very important prognostic indicators of breast cancer. The grading system that is well established is the Nottingham modification of Bloom Richardson’s grading system which takes into account architectural features (mainly tubule formation), the degree of nuclear atypia and evaluation of mitotic activity. In this system, only the mitotic activity is evaluated in a quantitative manner, while the evaluation of nuclear pleomorphism and tubule formation is still dependent on the pathologist's subjective factors. To improve the clinical value of malignancy grading, it has been suggested to quantify nuclear pleomorphism by measuring nuclear features such as area, perimeter and diameters. Various attempts quantitating these changes (particularly the nuclear aberration) have been made by computer analysis. Computer assisted nuclear morphometry helps in objective grading of breast cancer and reduces the interobserver variability. Objectives: The aim of the study was to quantitate the nuclear pleomorphism in IDC (NOS) of breastby computer assisted nuclear morphometry and to correlate values obtained with other established prognostic indicators. Materials and methods: Sixty cases of mastectomy specimens with proved histological diagnosis of IDC (NOS) were subjected to the study. Computerised Nuclear morphometry was done by using Olympus BX-41 research microscope with jenoptix (Germany) progress CCD camera with progress capture pro imaging software. Fifty nuclei from each case were outlined using the sketch command under 0.00001 increments by the computer mouse. Results: As the grade of tumour increased, the morphometric values increased. A statistically significant correlation was obtained between the morphometric size parameters and histological prognosticators. No correlation was found between morphometric shape parameters and prognostic factors. Conclusion: Computer assisted morphometry can be used in objective grading and standardizing grading performance between different laboratories.
Kronik ağri, psikolojik etmenler ve depresyon Chronic pain, psychological factors and depression

Chronic pain is a common health problem in clinical practice. Besides the increase in health-care expenditure, it also causes decline in patient’s functioning and working capability. In addition, chronic pain and psychiatric symptom comorbidity is very frequent. Recently there are many studies focusing on depression and pain. It might be just a symptom of depression, or might affect psychological status as a consequence of physical disorder. As a result, multidisciplinary approach is necessary for a successful treatment. In this review generally chronic pain, psychological factors and especially depressive disorders are summarized; and the multidisciplinary approaches to the diagnosis, assessment and treatment of the patient with chronic pain are overviewed. OZET
Bridging the research-practice gap

Health service redesign researchers from the National Institute for Health Research Collaborations for Leadership in Applied Health Research and Care for Birmingham and the Black Country (NIHR CLAHRC BBC) investigated the process of large scale service redesign. In order to engage clinical staff and service users in the study, and to ensure findings were disseminated as widely as possible, the team included professional communicators who helped to connect researchers and key stakeholders. The NHS ‘communications fellows’ provided expertise in professional communication approaches and links to a wider network of communications professionals. The use of a range of communications industry techniques was vital in establishing effective communication channels to share interim and final research findings. The benefits of using a selection of key techniques is examined and recommendations are made that could help other researchers capitalise on professional communication approaches to help ensure the impact of t.