Miracle-dz/UniFAR-FTUs huggingface dataset:
Investigatingthe Effect of Therapeutic Taping on Trunk Posture and Control in Cerebral Palsy Children with Spastic Diplegia

Background: Cerebral palsy (CP) is considered as the most common cause of postural problems and motor dysfunctions in neuro pediatrics. Purpose: This study aimed to investigate the effect of kinesiotape (KT) application on the trunk posture and control in children with spastic diplegic CP that were enrolled into physical therapy program. Methods: The study included 30 spastic diplegic children. Those with deformities that could disrupt the balance in sitting and standing were excluded. The patients were randomly divided into two equal groups. The control group received physical therapy programand study group received KT in addition to the same physical therapy program for 12 weeks. KT was appliedwith repetition for consecutivethree days and then removed leaving the skin free for 24 hoursduring the period of treatment.For metric instrumentation system was used to evaluate posture parameters: trunk imbalance, pelvic tilt, pelvic torsion, surface rotation, and lateral deviation, in addition to Growth motor functional measure-88 (GMFM-88) to assess the sitting (B) and standing (D) control. Balance was evaluated using pediatric Berg balance scale (PBBS). Results: The comparisons of the measurements of the two groups before and after the treatment showed that postural parameters, sitting control, standing control and balance were statistically significantly improved in both groups.Comparing the post treatment results, study group was more statistically significantly improved than the control group, in the previous parameters, except in pelvic torsion and surface rotation, there were no significant differences. Conclusion: It is suggested to apply KT ontrunk muscles along with the physical therapy program to improve trunk posture and control in cerebral palsy children of spastic diplegic type which is more effective than physical therapy alone.
Collaborating with Traditional Healers for HIV Prevention and Care in sub-Saharan Africa: suggestions for Programme Managers and Field Workers

The mention of specific companies or of certain manufacturers' products does not imply that they are endorsed or recommended by UNAIDS in preference to others of a similar nature that are not mentioned. Errors and omissions excepted, the names of proprietary products are distinguished by initial capital letters. UNAIDS does not warrant that the information contained in this publication is complete and correct and shall not be liable for any damages incurred as a result of its use. The designations employed and the presentation of the material in this publication do not imply the expression of any opinion whatsoever on the part of WHO Library Cataloguing-in-Publication Data Collaborating with traditional healers for HIV prevention and care in sub-Saharan Africa: practical guidelines for programmes. (UNAIDS best practice collection) " UNAIDS/06.28E ". 1.HIV infections – therapy 2.Acquired immunodeficiency syndrome – therapy 3.Medicine, African traditional – utilization 4.Program development 5.Practice guidelines 6.Models, Educational 7.Africa South of the Sahara I.Title II.Title: A practical guide for collaborating with traditional healers for HIV prevention and care in sub-Saharan Africa. Acknowledgements UNAIDS and the author express their sincere thanks to people living with HIV and other clients of healers and biomedical practitioners, as well as all the protagonists of past and present collaborations, for teaching us the value of partnership. We would also wish to convey our most respectful appreciation to the courageous individuals who are trying to forge a much-needed link between the traditional and biomedical health systems in Africa. Among them are those who contributed invaluable information for this document. In the same vein, we cannot thank enough Sandra Anderson for her unrelenting support in bridging the gap between African traditional and modern medicine. Last, but not least, we would like to express our profound respect to traditional healers throughout sub-Saharan Africa who have provided care to people over the centuries. We are indebted to them for what they are still teaching us today. Acknowledgements 2 List of abbreviations and acronyms 4 Using the guidelines 5 Executive summary 7 Introduction 9 From talk to action: 11 1. Starting with critical determinants of success and failure learned from documented collaborations 11 2. Building a generic, adaptable model to reach out to traditional healers and scale up collaborations in sub-Saharan Africa 19 A. Analysing context surrounding traditional medicine and aids 19
Gastric Pacing / Electrical Stimulation and Gastric Per Oral Endoscopic Myotomy

CPB 0678 Gastric Pacing / Electrical Stimulation / Per Oral Endoscopic Myotomy This CPB has been revised to state that gastric per-oral endoscopic myotomy (G-POEM) is considered experimental and investigational for the treatment of (i) gastroparesis; and (ii) congenital hypertrophic pyloric stenosis. The title of this CPB has been changed to “Gastric Pacing / Electrical Stimulation and Gastric Per Oral Endoscopic Myotomy”. Update History since the last PARP Submission: 03/07/2019-This CPB has been updated with additional background information and references.
The Star Studded Protein and its Chaperone Mediated Pathways: FaultyLysosomal-Autophagic System, Alpha-Synuclein Aggregates in Parkinson’sDisease and its Relevance to Therapeutic Intervention

Citation: Jeswinder Sian-Hulsmann. “The Star Studded Protein and its Chaperone Mediated Pathways: Faulty Lysosomal-Autophagic System, Alpha-Synuclein Aggregates in Parkinson’s Disease and its Relevance to Therapeutic Intervention”. EC Neurology 12.5 (2020): 46-49. Plethora of research findings over recent years have led to the elevation of α-synuclein to star status in the etiology of PD. Rogue pathogenic proteins such as α-synuclein, appear to play a malevolent role in the development of Parkinson’s disease(PD) and other α-synucleinopathies. They share a common denominator, which is characterised by aggregates of misfolded α-synuclein, which results in the formation of intra-neuronal inclusions known as Lewy bodies (LB). The presence of LB in substantia nigra is mandatory for the neuropathological diagnosis of PD. Interestingly, the occurrence of these structures appear to mirror areas exhibiting neuronal cell loss such as the substantia nigra pars compacta and other brain areas burdened with the onslaught of the disease, thereby suggesting that they are of focal relevance to the disorder. Furthermore, the presence of LB in the asymptomatic phase of PD (incidental Lewy body disease; [1] endorses their role in the pathogenesis. It is unclear whether they represent a cause or consequence of the illness. Therefore, in order to advocate effective therapeutic intervention it is imperative to elucidate the pathways or mechanism(s) underlying disruption of protein homeostasis, α-synuclein accumulation LB formation.
FAS Gene Mutation in a Case of Autoimmune Lymphoproliferative Syndrome Type IA With Accumulation of + T Cells

A 6-month-old girl presented to the hospital with cervical lymphadenopathy and hepatosplenomegaly. She was known to have an enlarged spleen, anemia, and thrombocytopenia since the age of 1 month. A lymph node biopsy showed a diffuse proliferation of blasts with few remnants of follicles. The blasts were CD3+CD57+CD4−CD8−, consistent with the usual autoimmune lymphoproliferative syndrome phenotype. However, these double negative T cells stained positive for T-cell receptors, whereas double negative T cells in patients with autoimmune lymphoproliferative syndrome usually bear T-cell receptor. Mutation analysis of the FAS gene revealed a mutation in the death domain of the FAS gene, which is a frequent finding in patients with autoimmune lymphoproliferative syndrome. Based on these results, the diagnosis of autoimmune lymphoproliferative syndrome was established. RTPCR analysis of the affected lymph node tissue revealed a strong upregulation of interleukin 10 and a moderate upregulation of interferonexpression compared with normal tissue. Our findings indicate that autoimmune lymphoproliferative syndrome can result in a prominent proliferation of + double negative T cells. It is important to distinguish this benign polyclonal proliferation from neoplastic + T-cell proliferations, such as hepatosplenic T-cell lymphomas. Factors contributing to the accumulation of these + double negative T cells may be an unidentified infection in combination with the young age of onset in this patient.
Osseous Metaplasia and Mature Bone Formation With ExtramedullaryHematopoiesisinTrichilemmalCyst

COMMENT Fluorescence microscopy of H&Estained specimens allows rapid visualization of elastic fibers at no added cost and without the delay inherent with special stains. Elastic fibers fluoresce in unstained frozen sections, but most of the bright fluorescence observed in H&E-stained sections is a result of the fluorescence of eosin. Variations in H&E staining can have a dramatic effect on the degree of eosinophilia and fluorescence of the surrounding collagen fibers. As a result, this technique cannot be utilized in laboratories with an “eosin heavy” H&E stain. Our study demonstrated that elastic fibers were well visualized and differentiated from other structures in the skin in less than one half of the cases because of the variations in our H&E stain over time. In those cases where the findings were interpretable, the pattern of elastic fiber distribution corresponded to that seen with EVG staining. Benign melanocytic nevi demonstrated preservation of elastic fibers, whereas melanomas lacked elastic fibers in the tumor stroma. Elastic fiber fluorescence was more suitable for dermal proliferations that extended into the reticular dermis because papillary dermal elastic fibers were difficult to visualize with this technique. A major limitation of our study is the small number of cases. Additional studies to validate reliability are needed before concluding that this low-cost technique should be used routinely to help distinguish benign from malignant melanocytic lesions.
Antimicrobial efficacy of commercially available plant essential oils with calcium hydroxide as intracanal medicaments against Enterococcus faecalis: An in-vitro study

Introduction: Persistent root canal infection by E. faecalis is the greatest hurdle to successful endodontic treatment. Plant essential oils possess strong antimicrobial activity that can be harnessed to eliminate this bacterium from the root canal environment. Methods: E. faecalis (ATCC 29212) was cultivated in BHI broth and incubated at 37 o C for 24 hours. Using cotton swabs, the bacterial suspension was inoculated on 30 Mueller Hinton Agar plates. Four wells were made in each agar plate and were filled with the test medicaments and incubated at 37 o C for 72 hours. Group A: Aniba rosaeodora and calcium hydroxide; Group B: Origanum vulgare and calcium hydroxide; Group C: Calcium hydroxide alone and Group D: Triple antibiotic paste. The zones of inhibition were obtained using Kirby-Bauer well diffusion method. Results: All the medicaments were found to be effective in inhibiting E. faecalis. Maximum inhibition was noted with Group D (27.4 ± 1.5 mm) followed by Group B (25.0 ± 1.0 mm) and Group C (22.2 ±0.9 mm). Group A showed least inhibitory activity. Conclusion: Essential oils in combination with calcium hydroxide can be used as an effective intracanal medicament against E. faecalis to prevent reinfection and improve longevity of root canal treatment. -------------------------------------------------------------------------------------------------------------------------------------Date of Submission: 23-05-2018 Date of acceptance: 05-06-2018 -------------------------------------------------------------------------------------------------------------------------------------
The Level of Knowledge of Healthcare Workers, Excluding Physicians, Regarding HIV, and Their Approach to People Living with HIV

Keşfedildiği günden beri, HİV virüsü insan ve toplum sağlığına olan etkisi nedeniyle global bir sorun teşkil etmektedir. Türkiye’de HİV ile yaşayan bireylerin sayısı her geçen yıl artmakla beraber, 2016 itibariyle 14000’i geçmiştir. HİV ile yaşayan bireyler dünyanın geri kalanında olduğu gibi Türkiye’de de stigmatizasyon ve ayrımcılığa maruz kalmaktadırlar. Yapılan çalışmalarda özellikle sağlık sektöründe bu damgalamanın etkileri görülmektedir. Sağlık çalışanlarının bilgi düzeyleri yeterli olmamakla beraber, HİV ile yaşayan bireylere olan yaklaşımlarının diğer hastalarla aynı olmadığı gözlemlenmiştir. Bu çalışmanın amacı, hekimler haricindeki sağlık çalışanlarının HİV ile ilgili bilgi düzeyleri ve HİV ile yaşayan bireylere yaklaşımlarını araştırmaktır.
CAUSAL NEXUS BETWEEN THE ANAMOLIES IN THE CRUDE OIL PRICE AND STOCK MARKET

The paper attempts to examine the causal association between the crude oil price anomalies and stock market returns in the Indian stock market. The study covers nine years starting from 2009 to 2018, and the study includes ten companies in the oil drilling and exploration sectors listed in the BSE SENSEX and CNX NIFTY indexes. We employed correlation tests in determining the relationships amongst the stock market return, crude oil price and market benchmarking indexes. Our study concludes that the oil price shocks is not directly affecting the stock prices of oil-related firms; instead, its indirectly impacting the economy through different channels such as fiscal, trade and price channels. We also suggest the need for future researches in determining the effect of oil price variations on the macroeconomic factors by precisely diagnosing the role of channels mentioned above.
The Burnout Condition of Primary Health Care Personnel

The concept of burnout was first introduced by Fredeunberger in 1974. Fredeunberger had stated that burnout occurred more commonly in occupations whose members directly work with people. The aim of the study is to examine the burnout status of primary health care staff. The universe of this descriptive study is 466 health staff who work in primary health care units in KeA§iA¶ren. The participation of the study was 54%. A Questionnaire including Maslach Burnout Inventory (MBI) and some characteristics of the participants were used for data collection. Mann-whitney U and Kruskal Wallis tests have been used for analizing the survey data. Seventyseven percent of the participants were female and the emotional exhaustion score of female was higher than male (p
Assessment of Female Sexual Function during Pregnancy

Background: Pregnancy is one of the most serious periods in women’s lives. The state of pregnancy is characterized by physical, hormonal and psychological changes which profoundly affect women’s sexuality. The aim: to assess female sexual function during pregnancy. Design: A descriptive design was used. Setting: This study was conducted at the antenatal care unit in Helwan general hospital. Sample: A purposive sample of 240 pregnant women was recruited and equally divided into first, second and third trimester. Tools: two tools were used for data collection in this study, tool I was self-administered questionnaire to collect data about sociodemographic characteristics, sexual health knowledge during pregnancy and effect of pregnancy on sexual function tool II was female sexual function index (FSFI) which was a validated and reliable measure of female sexual function Results: The study denoted that 77.5% of pregnant women had poor sexual health knowledge during pregnancy as well as 62% of pregnant women had sexual dysfunction during pregnancy. Conclusion: pregnancy had a negative effect on female sexual function as pregnancy progress. Recommendation: Sexual health counseling should be provided to all pregnant women during pregnancy as an essential part of routine antenatal care. Key Word: Sexual function, Pregnancy, Sexual health. ------------------------------------------------------------------------------------------------------------------------------------------Date of Submission: 20-02-2020 Date of Acceptance: 04-03-2020 ------------------------------------------------------------------------------------------------------------------------------------------
Exercise and Health Effects Of Exercise On Insulin Resistance In South Asians And Europeans

G.J.G. Davey, J.D. Roberts, S. Patel, T. Pierpoint, I.F. Godsland, B. Davies and P.M. McKeigue. Effects Of Exercise On Insulin Resistance In South Asians And Europeans. JEPonline, 3(2):6-11, 2000. Insulin resistance underlies coronary heart disease and type II diabetes in South Asians and Europeans. We investigated whether exercise training could ameliorate insulin resistance, and whether any benefit depended on the timing of measurement in relation to exercise. Ninety-two sedentary South Asian and European men and women aged 35-49 years were recruited. After baseline measurements, subjects were randomized to one of three groups: no change in daily activity (NE), exercise with follow up insulin sensitivity measured within 24 hours of last exercise session (E1), and exercise with follow up insulin sensitivity measured five days after last session (E5). Insulin sensitivity was determined by minimal model analysis of glucose and insulin concentrations. Maximal oxygen uptake was measured using a graded exercise treadmill test based on a modified Bruce protocol. Data from E1 and E5 showed a significant increase in cardiorespiratory fitness compared to NE (+4.15 vs. -0.003 mL/kg/min, p<0.001). Insulin sensitivity was significantly improved only in E1 compared to NE or E5 (+0.67 vs. +0.30 min/pmol/L, p=0.05), representing a 40% mean increase on initial values. In conclusion, exercise improved insulin sensitivity by 40% among those in whom it was measured within 24 hours of the final exercise session. An effect of this magnitude has considerable implications for the prevention of non-insulin-dependent diabetes at the population level.
Pregabalin abuse among patients with chronic pain syndrome

Copyright: © Hashish RKH (2020). This Article is distributed under the terms of Creative Commons Attribution 4.0 International License *Corresponding Author(s): Rania Kamal Hassan Hashish Department of Forensic Medicine and Clinical Toxicology, School of Medicine, Suez Canal University Hospital, 4.5 Kilo of the round road, Ismailia, Egypt 15213 Tel: 0020-128-2691-648, Fax: 0020-6439-23-439; Email: Raniakhashish@yahoo.com Annals of Anesthesia and Pain Medicine
Coronavirus disease 2019 (COVID-19): the portrait of a perfect storm

The “novel” coronavirus disease 2019 (abbreviated “COVID-19”) is the third coronavirus outbreak emerging during the past two decades. This infectious disease, sustained by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), has been recently declared a global pandemic by the World Health Organization. Despite the concerning epidemiological burden, many people, including some policymakers, are underestimating this pandemic and are remaining enigmatically inactive against a human pathology which, for a combination of reasons, can be reasonably defined as a perfect storm (i.e., the “wrong virus” at the “wrong time”). These many paradigmatic aspects include SARS-CoV-2 structure and peculiar biology of infection, high risk of inter-human transmission, long incubation time combined with early and sustained viral load, existence of asymptomatic or mildly-symptomatic carriers, viral shedding for days after symptom relief, unfavorable progression towards respiratory distress and death in up to 5–10% of patients thus causing dramatic healthcare challenges, as well as environmental contamination. Last but not least, the combination of the current case fatality rate with the extraordinary number of people that could be potentially infected by SARS-CoV-2 would permit to estimate that the worldwide deaths for COVID-19 may even approximate those recorded during World War II if appropriate restrictive measures for preventing human-to-human transmission are not readily undertaken. Everybody should be inexcusably aware that this is not a drill, and that the consequences of inadequate action will be tragedy.
School management on the basis of character building in teaching learning process

This study aims at presenting school management model based on character building in teaching learning process. This survey research was conducted for 450 students at elementary schools in Jakarta in Indonesia. Structural Equation Modeling (SEM) was used in analyzing data. Study result found that model hypothesized was a good fit for the data. Other findings confirmed that teaching learning process preparation, teaching learning process, and teaching learning process closing are positively correlated with character building in teaching learning process. The three dimensions consisting of praying, connecting teaching material with good attitude development, and inspecting the student uniform neatness have positive correlation with preparation of teaching learning process. Teaching learning process can be predicted by teaching cooperation in teamwork, encouraging student to ask questions, and paying attention to student attitude. The three dimensions determining closing of teaching learning process are praying, greeting, and reflecting by integrating with character values. It can be concluded that the model of school management focusing on character building in teaching learning process proposed can be used by elementary schools in Jakarta to improve student character building.
Data Fusion for the Prediction of Elemental Concentrations in Polymetallic Sulphide Ore Using Mid-Wave Infrared and Long-Wave Infrared Reflectance Data

The increasing availability of complex multivariate data yielded by sensor technologies permits qualitative and quantitative data analysis for material characterization. Multivariate data are hard to understand by visual inspection and intuition. Thus, data-driven models are required to derive study-specific insights from large datasets. In the present study, a partial least squares regression (PLSR) model was used for the prediction of elemental concentrations using the mineralogical techniques mid-wave infrared (MWIR) and long-wave infrared (LWIR) combined with data fusion approaches. In achieving the study objectives, the usability of the individual MWIR and LWIR datasets for the prediction of the concentration of elements in a polymetallic sulphide deposit was assessed, and the results were compared with the outputs of low- and mid-level data fusion methods. Prior to low-level data fusion implementation, data filtering techniques were applied to the MWIR and LWIR datasets. The pre-processed data were concatenated and a PLSR model was developed using the fused data. The mid-level data fusion was implemented by extracting features using principal component analysis (PCA) scores. As the models were applied to the MWIR, LWIR, and fused datasets, an improved prediction was achieved using the low-level data fusion approach. Overall, the acquired results indicate that the MWIR data can be used to reliably predict a combined Pb–Zn concentration, whereas LWIR data has a good correlation with the Fe concentration. The proposed approach could be extended for generating indicative element concentrations in polymetallic sulphide deposits in real-time using infrared reflectance data. Thus, it is beneficial in providing elemental concentration insights in mining operations.