Miracle-dz/UniFAR-FTUs huggingface dataset:
Value of E-cadherin and desmin immunohistochemistry in distinguishing metastatic adenocarcinoma from reactive mesothelial hyperplasia in serous effusion

IntroductionOne of the problems in studying serous effusion cytological samples is differentiation of reactive mesothelial cells from metastatic adenocarcinoma cells. PurposeThe purpose of this research was to study the immunohistochemical diagnostic value of E-cadherin (ECAD) and desmin markers in differentiation of these two groups of cells. Patients and methodsSeventy cases of serous effusions were examined as Papanicolaou-stained and Diff quick-stained smears, as well as paraffin-embedded cell blocks. Forty-three cases were diagnosed as metastatic adenocarcinoma and 27 cases were diagnosed as reactive mesothelial hyperplasia with typical cytomorphologic features. All the cases were studied for ECAD and desmin immunoreactivity. ResultsAll cases of metastatic adenocarcinoma reacted to ECAD and only four cases reacted to desmin, whereas among the 27 cases of reactive mesothelial hyperplasia 25 cases were stained with desmin and only two cases were stained with ECAD. ConclusionThe use of this short panel can be helpful for better differentiation of adenocarcinoma and reactive mesothelial hyperplasia in serous effusions, and it helps avoid overdiagnosis of metastatic adenocarcinoma because of the high sensitivity of ECAD.
Strategy Selection for Moving Target Defense in Incomplete Information Game

: As a core component of the network, web applications have become one of the preferred targets for attackers because the static configuration of web applications simplifies the exploitation of vulnerabilities by attackers. Although the moving target defense (MTD) has been proposed to increase the attack difficulty for the attackers, there is no solo approach can cope with different attacks; in addition, it is impossible to implement all these approaches simultaneously due to the resource limitation. Thus, the selection of an optimal defense strategy based on MTD has become the focus of research. In general, the confrontation of two players in the security domain is viewed as a stochastic game, and the reward matrices are known to both players. However, in a real security confrontation, this scenario represents an incomplete information game. Each player can only observe the actions performed by the opponent, and the observed actions are not completely accurate. To accurately describe the attacker’s reward function to reach the Nash equilibrium, this work simulated and updated the strategy selection distribution of the attacker by observing and investigating the strategy selection history of the attacker. Next, the possible rewards of the attacker in each confrontation via the observation matrix were corrected. On this basis, the Nash-Q learning algorithm with reward quantification was proposed to select the optimal strategy. Moreover, the performances of the Minimax-Q learning algorithm and Naive-Q learning algorithm were compared and analyzed in the MTD environment. Finally, the experimental results showed that the strategy selection algorithm can enable defenders to select a more reasonable defensive strategy and achieve the maximum possible reward.
We Don’t Need Another Hero: Understanding Team Learning Processes within the Senior Leadership Teams of Middle Atlantic Universities

WE DON’T NEED ANOTHER HERO: UNDERSTANDING TEAM LEARNING PROCESSES WITHIN THE SENIOR LEADERSHIP TEAMS OF MIDDLE ATLANTIC UNIVERSITIES Nicole Monique Woods The twin forces of complexity and change have created a volatile environment for higher education institutions. For many institutions, strategic institutional change has become an imperative, not a choice. These new demands have escalated the complexity of institutional leadership and changed the demands on the college and university presidency. Strategic responsibilities have expanded beyond the presidency in new ways, creating increased reliance by presidents on their senior leadership teams. In light of the key influence of senior leadership teams on strategic institutional change, a deeper investigation of these teams is critical for the sector’s positive transformation. This qualitative study of presidents and senior leadership teams at five Middle Atlantic higher education institutions sought to understand how presidents and their senior leadership team members work and learn together. The study was especially focused on the ways presidents and senior leadership team members described their roles, interactions between team members, and the practices and beliefs that inhibit or enable team learning. Using shared leadership, team learning, and sensemaking literature coupled with the Dechant, Marsick, and Kasl (1993) model of team learning as a foundation, the researcher conducted semi-structured interviews and administered an excerpt of the Dechant and Marsick (1993) Team Learning Survey. The study yielded insights that could be valuable to those who lead or are members of higher education senior leadership teams and those that educate, consult, and advise senior leadership teams in college and university settings. While strategic planning and long-term thinking were identified as key roles for senior leadership teams, team interactions were largely defined by institutional management activities, including information sharing, determining ownership and key decision makers, problem solving, and issue resolution. In particular, student affairs and finance officers reported fragmented learning processes and fixed views of their functional expertise. Senior leadership teams were primarily engaged in learning processes to support complex problem solving. To execute strategic change in higher education, intentionally cultivated informal learning practices that encourage explicit reflection on action coupled with deeper forms of relationship building between team members are needed. These activities require clear endorsement and consistent support by the institutional president.
Integrating sustainability into the multi-criteria assessment of urban dietary patterns

Abstract This study develops a decision-making procedure to help policymakers compare alternative patterns for sustainable diets by reaching a compromise among three criteria: socio-economic perspective, health and environment (including carbon and water footprints). An Analytical Hierarchy Process (AHP) was performed in several stages. First, a total of 25 stakeholders (members of organizations on the Valencia Food Policy Council) evaluated criteria that are relevant to the sustainability of diets. Secondly, a workshop with 14 experts from different backgrounds evaluated by consensus four dietary alternatives: Mediterranean, flexitarian, pescatarian and vegan. In terms of environment, experts gave priority to the vegan diet. However, the Mediterranean diet pattern (MDP) appeared, according to the process, as the most suitable pattern from the holistic perspective that integrates all relevant criteria. The MDP was ranked first in terms of the health criterion and the socio-economic perspective. These include culture, affordability, social impact and local production as decision elements that food policy advisory bodies take into consideration to define sustainable diets.
H-Terminated Diamond Surface Band Bending Characterization by Angle-Resolved XPS

Concerning diamond-based electronic devices, the H-terminated diamond surface is one of the most used terminations as it can be obtained directly by using H2 plasma, which also is a key step for diamond growth by chemical vapour deposition (CVD). The resultant surfaces present a p-type surface conductive layer with interest in power electronic applications. However, the mechanism for this behavior is still under discussion. Upward band bending due to surface transfer doping is the most accepted model, but has not been experimentally probed as of yet. Recently, a downward band bending very near the surface due to shallow acceptors has been proposed to coexist with surface transfer doping, explaining most of the observed phenomena. In this work, a new approach to the measurement of band bending by angle-resolved X-ray photoelectron spectroscopy (ARXPS) is proposed. Based on this new interpretation, a downward band bending of 0.67 eV extended over 0.5 nm was evidenced on a (100) H-terminated diamond surface.
Manufacturing Sector Performance And Economic Growth In Nigeria

The paper attempted to examine the impact of manufacturing sector output on economic growth in Nigeria from 1981 to 2016. The study employed secondary data sourced from the Central Bank of Nigeria statistical bulletin for Autoregressive Distributed Lag (ARDL) model and the Granger causality techniques on RGDP, manufacturing capacity utilization (MCU), manufacturing output (LMO), government investment expenditure (GINVEXP), money supply (LM2) and interest rate (INR). Evidence of long-run and short-run relationships among the variables was established. The results showed that MCU has positive influence on RGDP while LMO also affects RGDP positively. It also showed that GINVEXP has negative effects on RGDP whereas LM2 influenced RGDP positively. Moreover, the result indicated a unidirectional causality between RGDP and MCU, LMO and LM2. Based on the above, the study suggest government should intensify efforts to promote socio-economic infrastructural, macroeconomic and institutional framework in Nigeria to provide favourable environment for external and domestic institutions interactions; so harnessed mobilized funds effectively towards productive manufacturing sector.
Shanidar Cave - An Interesting Archaeological Site in the Kurdistan Region, Iraq

Shanidar Cave is one of the most well-known caves in Iraqi Kurdistan Region. It is an archaeological site located within Bradost Mountain north of Erbil city. Eleven skeletons of Neanderthals, have been found within the cave dating back to 65000 – 35000 years, they were called Shanidar (1 – 11). The cave also contains two later "proto-Neolithic" cemeteries.
Diet, Obesity, and Diabetes in Suburban Nepal - A Community-Based Study

Background: About one-fourth of Nepalese adults are estimated to be overweight or obese. No studies have examined the risk factors for obesity, especially pertaining to diet, in Nepal. Objective: The present study aimed to identify dietary patterns in a suburban Nepalese community and to assess their association with overweight and obesity prevalence. Methods: This cross-sectional study utilized data from the 1,073 adults (18 years or older) participating in the baseline survey of the Dhulikhel Heart Study. We derived major dietary patterns from the dietary intake using a validated food frequency questionnaire by using principal component analysis. Overweight was defined as BMI of 25 kg/m or higher and obesity was defined as BMI of 30kg/m or higher. Weight was measured using an Omron Model HBF-400 scale and recorded to the nearest 0.1 pounds. Height was measured using a standard tape with participants standing against a wall and recorded to the nearest 0.1cm. Statistical analysis was conducted using the generalized estimating equation (GEE) with multivariate logistic regression (with household as cluster) adjusting for age, sex, ethnicity, religion, marital status, income, education, alcohol consumption, smoking, physical activity, and systolic blood pressure. Results: Four dietary patterns were derived: mixed, fast food, refined grain-meatalcohol, and solid fats-diary. The refined grain-rice-alcohol pattern was positively associated with overweight (aOR 1.19, 95% CI: 1.03 – 1.39; p =0.02) after adjusting for demographic and traditional cardiovascular risk factors. We found a significant
The rifampicin-inactivating mono-ADP-ribosyl transferase of Mycobacterium smegmatis significantly influences reactive oxygen species levels in the actively growing cells

A classic example of antibiotic inactivating function in bacteria is the Mycobacterium smegmatis (Msm) encoded rifampicin-inactivating mono-ADP-ribosyl transferase (arr). Since its probable biological role has been proposed to be in DNA damage response, which is inflicted by reactive oxygen species (ROS), in the present study, we examined whether Msm Arr influences ROS levels. For this purpose, the levels of the ROS, hydroxyl radical and superoxide, were determined in the mid-log phase (MLP) cells of Msm arr knockout (arr-KO) strain, in comparison to those in the equivalently grown Msm arr+ wild-type (WT) strain. The MLP arr-KO cells generated significantly elevated levels of superoxide and hydroxyl radical, unlike the equivalently grown WT MLP cells. Complementation of arr-KO with arr, but not with empty vector, restored the ROS levels comparable to those in the WT strain. Elevated ROS levels in the arr-KO strain enabled selection of rifampicin-resistant mutants at 10-7 cfu/ml from the rifampicin-unexposed MLP cells of arr-KO, which is one-log10 higher than that for WT cells (10-8). Upon prolonged exposure to rifampicin, the susceptibility, persister formation, generation of elevated levels of hydroxyl radical by the persisters, rifampicin-resister generation frequency of the persisters and regrowth of the rifampicin-resistant mutants from the respective persisters were all comparable between the arr-KO and WT strains. These observations revealed that Arr influences ROS levels in the actively growing M. smegmatis cells but not in the rifampicin-exposed cells. We proposed the probable pathway through which Arr might be influencing ROS levels in the actively growing M. smegmatis cells. IMPORTANCE Diverse genera of bacteria consisting of pathogens, opportunistic pathogens and non-pathogens, possess Arr-type activities that confer equally efficient rifampicin resistance, thereby posing serious health hazard. Acquisition of this function by other bacteria through horizontal gene transfer enhances the hazard posed by the bacteria possessing it. M. smegmatis is an opportunistic human pathogen that causes infections of skin and soft tissues. Moreover, M. smegmatis is a genetically tractable model organism for M. tuberculosis with the potential to function even as tuberculosis vaccine. In view of these significant aspects of Arr and M. smegmatis, the study to find out the natural physiological role of Arr in M. smegmatis, gains importance for designing strategies to prevent antibiotic inactivation and to target the cellular function to contain the bacterium. Above all, the three-dimensional structure of M. smegmatis Arr reveals significant structural homology with eukaryotic ADP-ribosyltransferases and bacterial toxins, thereby giving the study broad significance.
Medicinal plants used in hepatic dysfunction

This study aimed to perform a survey about medicinal plants used in the treatment of the hepatic dysfunction commercialized by healers (salespeople) in the Sao Jose Market - Recife/Pernambuco and Sao Joaquim Street Market in Salvador/Bahia - Brazil. The place to obtain them, preparation methods and used parts of the medicinal plants, knowledge about plants, age and gender of the healers were also investigated. Eleven semi-structured interviews were performed on the healers in the Sao Jose Market. The most cited species was Croton rhamnifolioides (33.3%), 100% of the healers bought the plants, 100% indicated the preparation of teas, 85.7% the use of the leaves; 45.5% obtained knowledge about medicinal plants through experience with sales, with an average age of 42.8 years, 54.5% were male and 44.5% were female. On the other side of the Sao Joaquim Street Market, six interviews were performed. Vernonia condensata had 50% of citations, 100% of the healers bought the plants, 100% indicated the preparation of teas, 60% the use of leaves; 83.3% learned through experience with sales, and had a mean age of 39.5 years, 54.5% were male and 44.5% were female. This study may contribute to a better use of these resources by the people and useful in the registration and cataloging of information about medicinal plants. Key words: Croton, ethnobotany, liver, Vernonia.
The Influence of Breed and Type of Extender on the Quality of Bull Semen

This study aimed to determine the influence of breed and type of extenders on frozen semen quality of cows at BIB Lembang. The experimental study was conducted in a Factorial Randomized Block Design (RBD) with two factors. The first factor was four cow breeds, i.e. Ongole Cross (PO), Brahman (BR), Simmental (SM) and Limousin (LM), and the second factor was two types of extender, i.e. Skim-Egg Yolk (SKT) and AndroMed® (AND), all repeated four times. The observed variables were percentage of spermatozoa motility and intact plasma membrane (IPM). All data obtained were analyzed using a general linear model (IBM SPSS ver. 23). The results demonstrated an interaction between breed and the type of diluent to motility. Breeds showed significantly different motility but non-significantly different intact plasma membrane (MPU) of semen. The type of diluent did not significantly affect motility and intact plasma membrane (MPU) of the frozen semen. The effect of the breed on BR motility was lower and significantly different from PO, LM and SM. The types of diluent did not significantly affect motility, MPU. The results showed that SKT was lower than AND, it was indicative effect of breed on intact plasma membrane (MPU) PO was lower than BR, LM and SM and the effect of the type of diluent on whole plasma membrane (MPU) AND is lower than SKT. It can be concluded that breed influences the motility of semen. The lowest motility reduction in frozen semen is Brahman cattle by using skim-egg yolk extender.
Women-NGOS and financial viability: implications for women empowerment processes from a social work perspective

This paper examines the challenges associated with women-NGOs’ financial inadequacy as agents of women empowerment processes in Zimbabwe. With the utility of a resource-dependency theory and a qualitative paradigm, the study discovered that some women-NGOs were downsizing and/or closing due to financial paucity; most of them were skeletal in nature, compromising on coverage. The study also problematizes the donor-dependency syndrome of women-NGOs in Zimbabwe leading to a discourse on the sustainability of these NGOs. The discussion through social work lenses recommended immense advocacy for gender-sensitive policies which can facilitate gender mainstreaming efforts being made by the civil society in light of the current political-economic challenges. A plea for good governance, accountability and a paradigm shift towards developmental interventions aligned to a more integrated approach to solving socio-economic ills is also made in line with the tenets of developmental and critical social work. Keywords: Financial paucity; Donor-dependency; Women empowerment; Social work; Zimbabwe
Handbook Of Legumes Of World Economic Importance

Thank you very much for reading handbook of legumes of world economic importance. As you may know, people have search numerous times for their chosen readings like this handbook of legumes of world economic importance, but end up in harmful downloads. Rather than enjoying a good book with a cup of coffee in the afternoon, instead they are facing with some harmful virus inside their desktop computer.
Consistent floor response spectra for performance‐based seismic design of nonstructural elements

The achievement of adequate performance objectives for buildings under increasing seismic intensities is not only related to the performance of structural members but also to the behavior of nonstructural elements. The need to properly design nonstructural elements for earthquakes has been largely demonstrated in the last few years and has become an important objective within the earthquake engineering community. A crucial aspect in the proper design of nonstructural elements is the definition of the seismic demand in terms of both absolute acceleration and relative displacement floor response spectra. In the first part of this study, relative displacement and absolute acceleration floor response spectra were computed for four reinforced concrete moment‐resisting archetype frames via dynamic time‐history analyses and were compared with floor response spectra predicted by means of two recent simplified methodologies available in the literature. It was observed that one of the existing methodologies is generally unable to predict consistent absolute acceleration and relative displacement floor response spectra. An improved procedure is developed for estimating consistent floor response spectra for building structures subjected to low and medium‐high seismic intensities. This new procedure improves the predictions of a relative displacement floor response spectrum by constraining its ordinates at long nonstructural periods to the expected peak absolute displacement of the floor. The resulting acceleration and relative displacement response spectra are then consistently related by the well‐known pseudo‐spectral relationship over the entire nonstructural period range. The effectiveness of the proposed methodology was appraised against floor response spectra computed from nonlinear time‐history analyses.
Examining the Relationships Among Work–Life Constructs: A Review

Abstract Although there has been much research conducted on the work–life interface, the absence of an integrated review of its conceptualization is mystifying to many researchers. This study addresses this gap in the work–family research. The purpose of this article is to review and synthesize existing literature on the work–life interface. The article examines the conceptualization of the key constructs of work life interface, such as work–family conflict (WFC), work–family enrichment (WFE), and work–life balance (WLB), and draws differences among them. The study contributes to the work–family research by giving clarity about the meaning and relationship of work–life constructs. The study also gives an idea about the measures used in empirical work–life studies. The article concludes by suggesting propositions and a model which offers directions for future work–life researchers. The main limitation of this study is that it may have overlooked studies which are inaccessible or unpublished and having focused on research articles only in English. To the best of our knowledge, this study is among a few articles which attempted to understand the conceptualization of three work–life constructs simultaneously.
Educational Challenges in Ambulatory Pediatrics Teaching Programs Based on the Experiences of Interns and Attends: a Qualitative Study

1.Specialist in pediatrics, Associate Professor of pediatrics Dept., Isfahan University of Medical Sciences, Isfahan, Iran 2.General practitioner, M.Sc. in. Medical Education, Medical Educational Development Center, Isfahan University of Medical Sciences, Isfahan, Iran 3.Ph.D. In.Pharmacology, M.Sc. in Medical Education, Associate Professor of Medical Education Dept., Isfahan University of Medical Sciences, Isfahan, Iran  Received: 2 March, 2010  Accepted: 24 June , 2010