Miracle-dz/UniFAR-FTUs huggingface dataset:
User Terminal Planar Antennas for Wireless Broadband Access at K a Satellite Band

Millimetre waves satellite communications systems are emerging as a viable solution to provide global broadband coverage. This endeavour poses several new challenges for the antenna design. Radial Line Slot Array (RLSA) antenna is a conventional leaky wave antenna that can be adapted to the new speciﬁcations of ground or space terminals, featuring high gain, low proﬁle, and low cost. This work presents a comprehensive study on the design of RLSA’s, which requires an arrangement of a spiral like distribution of sub-wavelength slots in the upper plate of the circular parallel plate waveguide that compose the antenna. There is a wide variety of trade-oﬀs to be considered in terms of the radiation and aperture eﬃciencies, bandwidth, cross-polarization, side lobe level and return losses. To have a systematic design method, two tools were developed: i) a GO/PO (Geometric Optics/ Physical Optics) framework for deﬁning the antenna geometry; ii) a macro procedure that constructs the CAD (Computer Aided Design) model of the antenna for the full-wave analysis. Two antenna designs are presented in this work operating at 29.1 GHz: a RLSA that produces a boresight collimated beam with a 29.3 dBi gain; a second design that generates a 25.4 º oﬀset collimated beam with 26.4 dBi gain. Both designs have a diameter of 150 mm with only 1.61mm of height. A cavity-based feeding structure was also developed and optimized in order to simplify the manufacturing complexity of the RLSA antennas. Prototypes are being fabricated and measured, aiming to experimentally validate the promising full-wave results.
Toxic Effect Of Bisphenol A On Human Spermatozoa And Its Amelioration By Quercetin: In Vitro Study

Bisphenol A is a well-known xenoestrogen, present in large number of household products. Experimental studies suggests that BPA causes negative health effect in humans and animals. Quercetin, a flavonol occurring in fruit and vegetables is a food component with proven beneficial impact on health. Semen sample were treated with bisphenol A and its effects were observed on sperm functional parameters. Aim of present study was to analyze the dose dependent and time dependent effect of bisphenol A on human spermatozoa. Sperm suspensions were prepared from Semen collected from 10 healthy adult donors. BPA treated tubes containing 0.5 ml of sperm suspension and different concentrations of BPA (25-200 μg/ml). In another experiment different concentrations of quercetin (0-30 μg/ml) along with BPA (200 μg/ml) added in sperm suspensions. BPA treatment shows dose dependent and time dependent reduction in motility and viability of spermatozoa. Quercetin administration shows amelioration in the sperm parameters. The outcomes conclude that BPA have spermatotoxic effect in in vitro condition which can be mitigated by quercetin.
A Comparative Study Of Retention Of Mandibular Denture Base Without Air-Particle Abrasion, After Air-Particle Abrasion Of Intaglio Surface And After Immersion Of Air-Abraded Base In Artificial Saliva For 7 Days – An In Vivo Study

Dr. Abhay Haresh kumar Machchhar, Dr. Rupal Jaydip Shah, Dr. Sanjay Balaji Lagdive, Dr. Sherin Cherian 3 year Post-graduate student, Dept. of Prosthodontics, Govt. Dental College and Hospital, Ahmedabad. Professor and Head of Department, Dept. of Prosthodontics, Govt. Dental College and Hospital, Ahmedabad Professor, Dept. of Prosthodontics, Govt. Dental College and Hospital, Ahmedabad 3 year Post-graduate student, Dept. of Prosthodontics, Govt. Dental College and Hospital, Ahmedabad
Adaptive Riding Incorporating Cognitive-Behavioral Elements for Youth with Anxiety: An Exploratory Randomized Controlled Study

Between 15% to 20% of youth meet diagnostic criteria for anxiety, yet most do not receive treatment due to workforce shortages, under-detection, or barriers that dissuade families from seeking services in traditional settings. Equine-assisted services (EAS) include several promising approaches to reach populations who do not access traditional therapies. Few studies using rigorous methods have been conducted on EAS for youth. This study examined feasibility and outcomes of a 10-session Cognitive Behavioral Therapy (CBT)-based adaptive riding intervention (hereafter called Reining in Anxiety) delivered by trained equine professionals. Forty-one youth 6-16 years of age were recruited from GallopNYC, an adaptive horseback riding center in the NYC metro area. Youth were randomized to an experimental group (n=22) or services as usual (n=19), a standard adaptive riding group (services as usual or SAU). Severity of anxiety symptoms, anxiety in close relationships, and emotional self-efficacy were assessed at baseline and at the end of treatment. Fidelity to the manual was excellent, ranging from 88.9% to 100%. There was a non-significant trend in the experimental group towards greater improvement with higher number of sessions completed. Youth in the Reining in Anxiety group displayed significant reductions in anxiety (t=4.426, df=38, p=0.042) and improvement in emotional self-efficacy at posttest (t=4.132, df =38, p=0.049) in comparison to the SAU group. No significant differences were found between groups for anxiety in close relationships. This study suggests that a CBT-based adaptive riding intervention delivered by non-mental health equine professionals following a detailed manual can reduce youth anxiety symptoms and be delivered with fidelity by riding instructors. These findings have implications for families seeking non-traditional services.
Malnutrition on admission increases the in‐hospital mortality and length of stay in elder adults with acute ischemic stroke

Malnutrition, as determined by the Controlling Nutritional Status (CONUT), has an effect on the 3‐month and long‐term prognosis of stroke patients. The association between malnutrition and in‐hospital mortality has not been well established. We aimed to investigate the relationship between the CONUT score on admission and in‐hospital mortality and length of stay (LOS) in elderly patients with acute ischemic stroke (AIS).
Audio describing films : A first look into the description process

This article uses the data gathered in an experiment carried out to investigate audio description decision-making processes to analyse the scripting process of audio description for films. As part of the study, describers from Poland and Spain prepared audio description for ten clips from Polish and Spanish films. Data was collected through a multi-method approach, which included keylogging, think-aloud verbalisations, screen and face recording. Results, based on a qualitative analysis of screen and face recordings and think-aloud protocols, show that the audio description scripting process resembles operations involved in both writing and translating, and may be divided into three main processes (pre-drafting, drafting and post-drafting) and seven intertwining subprocesses (understanding, planning, searching, generating text, revising, reviewing, and cueing).
Evaluation of the Effects of Alomo Bitters on Albino Rats

This study was designed to evaluate the effects of Alomo bitters on albino rats. The Alomo bitters was fed using an oro-gastric gavage, to different sets of male albino wistar rats, after which the biochemical and haematological indices and histopathological status of the organs of the bitters -fed rats, as well as the acute toxicity (LD 50 ) and subchronic toxicity of the Alomo bitters on the rats were investigated using standard laboratory procedures. The Alomo bitters were well tolerated and not toxic to the rat organs and blood cells, during the 28-day duration of the study. The acute toxicity (LD 50 ) of 29 x 10 3 mg/kg body weight indicates it has low-lethality. The minimal and non-significant differences (P>0.05) in all the indices used to assess, the liver, kidney and cardiac function statuses of the Alomo-fed rats compared to same in the control rats, was indicative that the Alomo preserved the functions of these organs. The increase in the CD 4+ -count and decrease in the level of the fasting blood glucose in the Alomo-fed rats when compared to that of the control rats was significant (P<0.05). The decrease in serum triacylglycerol and LDL-cholesterol levels and the increase in HDL-cholesterol caused by the bitters was significant (P<0.05). The Alomo-fed rats had a significant decrease (P<0.05) in their serum malondialdehyde (MDA) levels and a significant increase (P<0.05) in their serum vitamin C and E levels and activities of antioxidant enzymes namely superoxide dismutase, catalase, and glutathione peroxidase, when compared with that of the control rats.
Drainage system and thermal structure of a High Arctic polythermal glacier: Waldemarbreen, western Svalbard

Abstract Understanding glacier drainage system behaviour and its response to increased meltwater production faces several challenges in the High Arctic because many glaciers are transitioning from polythermal to almost entirely cold thermal structures. We, therefore, used ground-penetrating radar data to investigate the thermal structure and drainage system of Waldemarbreen in Svalbard: a small High Arctic glacier believed to be undergoing thermal change. We found that Waldemarbreen retains up to 80 m of temperate ice in its upper reaches, but this thickness most likely is a relict from the Little Ice Age when greater ice volumes were insulated from winter cooling and caused greater driving stresses. Since then, negative mass balance and firn loss have prevented latent heat release and allowed near-surface ice temperatures to cool in winter, thus reducing the thickness of the temperate ice. Numerous reflectors that can be traced up-glacier are interpreted as englacial channels formed by hydrofracturing in the crevassed upper region of the glacier. The alternative cut and closure mechanism of conduit initiation only forms conduits in parts of the lower ablation area. Consequently, Waldemarbreen provides evidence that hydrofracturing at higher elevations can play a major role in englacial water drainage through cold ice.
Targeted FGFR/VEGFR/PDGFR inhibition with dovitinib enhances the effects of nab-paclitaxel in preclinical gastric cancer models

ABSTRACT Standard chemotherapy regimens for gastric adenocarcinoma (GAC) have limited efficacy and considerable toxicity profiles. Nab-paclitaxel has shown promising antitumor benefits in previous GAC preclinical studies. Dovitinib inhibits members of the receptor tyrosine kinase family including FGFR, VEGFR and PDGFR, and has exhibited antitumor effects in many solid tumors including GAC. Based on the antimitotic, antistromal and EPR effects of nab-paclitaxel, we investigated augmentation of nab-paclitaxel response by dovitinib in multiple GAC preclinical models. In MKN-45 subcutaneous xenografts, inhibition in tumor growth by nab-paclitaxel and dovitinib was 75% and 76%, respectively. Dovitinib plus nab-paclitaxel had an additive effect on tumor growth inhibition and resulted in tumor regression (85% of its original value). Dovitinib monotherapy resulted in minimal improvement in animal survival (25 days) compared to control (23 days), while nab-paclitaxel monotherapy or dovitinib plus nab-paclitaxel combination therapy led to a clinically significant lifespan extension of 83% (42 days) and 187% (66 days), respectively. IHC analysis of subcutaneous tumors exhibited reduced tumor cell proliferation and tumor vasculature by dovitinib. In vitro studies demonstrated that dovitinib and nab-paclitaxel individually reduced tumor cell proliferation, with an additive effect from combination therapy. Immunoblot analyses of MKN-45 and KATO-III cells revealed that dovitinib decreased phospho-FGFR, phospho-AKT, phospho-ERK, phospho-p70S6K, phospho-4EBP1, Bcl-2 and increased cleaved PARP-1, cleaved-caspase-3, p27, Bax, Bim, with an additive effect from combination therapy. These results demonstrate that the FGFR/VEGFR/PDGFR inhibitor, dovitinib, has the potential to augment the antitumor effects of nab-paclitaxel, with implications for use in the advancement of clinical GAC therapy.
Electrochemical CO2 Reduction Reaction over Cu Nanoparticles with Tunable Activity and Selectivity Mediated by Functional Groups in Polymeric Binder

The electrochemical carbon dioxide reduction reaction (CO2RR) using copper (Cu)-based catalysts has received significant attention mainly because Cu is an element capable of producing hydrocarbons and oxygenates. One possible way to control the CO2RR performance at the electrode interface is by modifying catalysts with specific functional groups of different polymeric binders, which are necessary components in the process of electrode fabrication. However, the modification effect of the key functional groups on the CO2RR activity and selectivity is poorly understood over Cu-based catalysts. In this work, the role of functional groups (e.g., −COOH and −CF2 groups) in hydrophilic and hydrophobic polymeric binders on the CO2RR of Cu-based catalysts is investigated using a combination of electrochemical measurements, in situ characterization, and density functional theory (DFT) calculations. DFT results reveal that functional groups influence the binding energies of key intermediates involved in both CO2RR and the competing hydrogen evolution reaction, consistent with experimental observation of binder-dependent product distributions among formic acid, CO, CH4, and H2. This study provides a fundamental understanding that the selection of desired polymeric binders is a useful strategy for tuning the CO2RR activity and selectivity.
Evaluation of patient social support, caregiver burden, and their relationship with the course of the disease in patients with bipolar disorder

Background: Bipolar disorder is a chronic disorder that causes significant effects on the patient and exerts a significant care burden on caregivers. This study aimed to investigate the social support of patients, caregivers’ burden and their impact on the clinical course of the disease. Methods: The study included 85 patients with bipolar disorder type I and II (in the recovery phase of the disease) and their caregivers in the age range of 18 to 60 years. It was conducted in Shafa psychiatry Hospital in Rasht (Guilan, Iran, 2020). To assess social support and burden, patients and caregivers completed the Multidimensional Perceived Social Support Scale (MSPSS) and Caregiver Burden Inventory (CBI), respectively. Clinical variables were also obtained from patients’ medical records; Then ANOVA, MANOVA, Independent T-test were used to compare the data and Regression Analysis and Spearman correlation coefficient were used to find the relationships between variables. Results: It was showed that increasing patient social support is associated with reducing caregiver burden. Among the clinical variables, less social support and more caregiver burden were associated with longer duration of illness (p < .0029, p < .012), decrease in last recurrence time (p < .0013, p < .0001), increased number of hospitalizations (p < .0001, r = −.43 and p < .0001, r = +.49), decreased response to treatment (p < .0001, p < .0001), and reduced follow-up (p = .001, OR = 1.12 and p = .001, OR = 0.95). Conclusion: The relationship between low social support and high caregiver burden and their significant effect on the disease course indicates a vicious cycle that affects patients, caregivers, and the clinical course of the disease. Therefore, it seems that interventions to break this cycle can change the situation in favor of patients and caregivers and improve the clinical course of the disease.
School Variables as Determinants of Students’ Academic Performance in Public Secondary Schools in Ebonyi State, Nigeria

The study investigated school variables as determinants of students’ academic performance in public secondary schools in Ebonyi State, Nigeria. Three research questions and three hypotheses guided the study. The descriptive survey design was adopted for the study. The population of the study comprised 5,676 teachers in public secondary schools in Ebonyi State. Four hundred (400) teachers in public secondary schools constituted the sample of the study. Proportionate stratified random sampling technique was used to select the sample size. A four point structured 15-item rating scale questionnaire titled, “School Variables Questionnaire (SVQ)”, was constructed by the researcher and used to collect data for the study. The data collected were analyzed using mean and standard deviation to answer research questions while chi-square (x 2 ) test statistic was used to test the hypotheses at 0.005 level of significance. The study revealed that there was a significant influence of infrastructural facilities, class-size and school location on students’ academic performance in public secondary schools in Ebonyi State, Nigeria. It was recommended among other things that there should be schools and communities partnership and collaborations in the provision and maintenance of infrastructural facilities as there would complement the efforts of the government in enhancing quality education.
In Vitro Schistosomicidal Activities of the Leaf Extracts from Casearia sylvestris Varieties

Schistosomiasis, a tropical disease caused by flatworms, may affect the liver, spleen, bladder, and intestine. Casearia sylvestris Swartz, a medicinal plant, displays antiprotozoal, antimicrobial, antifungal, and antiulcer activities. We have evaluated the in vitro schistosomicidal activity of two C. sylvestris varieties against Schistosoma mansoni adult worms at concentrations between 12.5 and 200 μg/mL. At 100 and 200 μg/mL, the ethanolic C. sylvestris var. sylvestris leaf extract enriched in casearin‐like diterpenes eliminated 100 % of the parasites after incubation for 72 h and 48 h, respectively, whilst the same extract at 200 μg/mL eliminated 96 %, 100 %, and 100 % of the parasites after incubation for 24, 48, and 72 h, respectively. On the other hand, the hydroalcoholic C. sylvestris var. lingua leaf extract at 200 μg/mL eliminated 60.4 and 66.7 % of the parasites after incubation for 48 and 72 h, respectively. The presence of casearin‐like diterpenes and glycosylated flavonoids was confirmed based on chromatographic techniques and mass spectrometry data.
Assessing Acceptability of COVID-19 Vaccine Booster Dose among Adult Americans: A Cross-Sectional Study

Given the emergence of breakthrough infections, new variants, and concerns of waning immunity from the primary COVID-19 vaccines, booster shots emerged as a viable option to shore-up protection against COVID-19. Following the recent authorization of vaccine boosters among vulnerable Americans, this study aims to assess COVID-19 vaccine booster hesitancy and its associated factors in a nationally representative sample. A web-based 48-item psychometric valid survey was used to measure vaccine literacy, vaccine confidence, trust, and general attitudes towards vaccines. Data were analyzed through Chi-square (with a post hoc contingency table analysis) and independent-sample t-/Welch tests. Among 2138 participants, nearly 62% intended to take booster doses and the remaining were COVID-19 vaccine booster hesitant. The vaccine-booster-hesitant group was more likely to be unvaccinated (62.6% vs. 12.9%) and did not intend to have their children vaccinated (86.1% vs. 27.5%) compared to their non-hesitant counterparts. A significantly higher proportion of booster dose hesitant individuals had very little to no trust in the COVID-19 vaccine information given by public health/government agencies (55% vs. 12%) compared to non-hesitant ones. The mean scores of vaccine confidence index and vaccine literacy were lower among the hesitant group compared to the non-hesitant group. Compared to the non-hesitant group, vaccine hesitant participants were single or never married (41.8% vs. 28.7%), less educated, and living in a southern region of the nation (40.9% vs. 33.3%). These findings underscore the need of developing effective communication strategies emphasizing vaccine science in ways that are accessible to individuals with lower levels of education and vaccine literacy to increase vaccination uptake.
Time dependent breakdown of ultrathin gate oxide

Time dependent dielectric breakdown (TDDB) of ultrathin gate oxide ( 4.8 MV/cm. The TDDB activation energy for this type of gate oxide was found to have linear dependence on oxide field. In addition, we found that /spl gamma/ (the field acceleration parameter) decreases with increasing temperature. Furthermore, it was found that testing at high temperatures (up to 342/spl deg/C) and low electric field values did not introduce new gate oxide failure mechanism. It is also shown that TDDB data obtained at very high temperature (342/spl deg/C) and low fields can be used to generate TDDB model at lower temperatures and low fields. Our results (an enthalpy of activation of 1.98 eV and dipole moment of 12.3 e/spl Aring/) are in complete agreement with previous results by McPherson and Mogul. Additionally, it was found that TDDB is exponentially dependent on the gate voltage.
Effects of norepinephrine on microglial neuroinflammation and neuropathic pain

Abstract Norepinephrine (NE) is an important neurotransmitter in the central nervous system. NE is released from locus coeruleus neurons and is involved in a variety of physiological and pathological processes. Neuroinflammation is a common manifestation of many kinds of neurological diseases. The activation of microglia directly affects the status of neuroinflammation. Several kinds of adrenergic receptors, which anchor on microglia and can be regulated by NE, affect the activation of microglia and neuroinflammation. NE influences chronic pain, anxiety, and depression by regulating the activation of microglia.
Benefits of Real-Time Transit Information and Impacts of Data Accuracy on Rider Experience

When presented in a practical format, real-time transit information can improve sustainable travel methods by enhancing the transit experience. This paper identifies the positive shift realized by the continued development of the OneBusAway set of real-time transit information tools. In addition, the paper analyzes real-time prediction errors and their effects on the rider experience. In 2012, three years after the development of location-aware mobile applications, a survey of current OneBusAway users was conducted to compare the results with the previous 2009 study. Results show significant positive shifts in satisfaction with transit, perceptions of safety, and ridership frequency as a result of the increased use of real-time arrival information. However, this paper also provides a perspective of the margin of error riders come to expect and the negative effects resulting from inaccuracies with the real-time data. Although riders on average will ride less when they have experienced errors, a robust issue-reporting system as well as the resolution of the error can mitigate the initial negative effects. With this understanding, the paper provides transit agencies and developers with guidance to realize the full potential of real-time information and error-reporting systems.