Miracle-dz/UniFAR-FTUs huggingface dataset:
Study of anaemia profile in a tertiary care hospital in Karnataka, India

Background: Anaemia is a major public health problem worldwide especially in developing countries like India. Nutritional cause of anaemia continues to predominate as the most common cause of anaemia. Objective of this study is to determine the clinical and laboratory profile of anaemia among patients admitted to our hospital. Methods: Our study was a prospective study in which thirty nine patients of anemia admitted to Medicine ward in SNMC and HSK hospital were studied for their clinical and laboratory characteristics. Duration of the study was 7 months from July 2019 to January 2020. Results: Anaemia was more common among females (65.1% of total patients). Patients aged less than 60 years contributed to 85% of patients. Pallor was the universal finding present in 100% of patients. On systemic examination haemic murmurs on auscultation was the most common finding present in 28.2% followed by hepatomegaly (17.94%). Microcytic and dimorphic anaemia constitute the bulk of anaemia. Conclusions: Nutritional anaemia particularly iron deficiency anaemia is the most common cause of anaemia. It tends to affect the working age group and females predominantly. Patients continue to present with severe anaemia to the hospital.
INFLUENCE OF CIGARETTE SMOKING ON SEMINAL PLASMA SOLUBLE FAS AS A MARKER OF GERM CELL APOPTOSIS

Background Male infertility constitutes about 50% of overall causes of infertility and apoptosis is known to have an essential role in the control of germ cell number in testis. Cigarette smoking is common in males at reproductive age. Studying the influence of smoking on apoptosis in male genital tract and its influence on fertility helps in the management of infertility in smokers. Objectives To assess the influence of cigarette smoking on seminal plasma (SP) soluble Fas (sFas) and the correlation between SP sFas and serum sex steroidal hormones and conventional semen parameters in males of infertile couples. Methods Seventy male partners of infertile couples (30 smokers and 40 non-smokers) were enrolled in this study. A subject was considered smoker if he had history of smoking of more 10 cigarettes per day for at least one year. Semen analysis was done according to World Health Organization (WHO) 2010. Specific kits were used for the measurement of SP sFas and serum testosterone and estradiol (E2). Results In smokers' group, SP sFas was significantly (p <0.05) negatively correlated with age and sperm motility and positively correlated with immotile sperm and round cell number. Conclusion Germ cell apoptosis in smoker males of infertile couples is interrelated with sperm motility.
Motivation in and of Work Teams: A Multilevel Perspective

Motivation in and of Teams: A Framework . 288 Generalizability of Motivational Concepts to the Team Level . 291 Motivational Processes: Goal Generation and Goal-Striving Processes . 291 Motivational States . 293 Research Needs . 296 Cross-Level Interplay Between Individual and Team Motivation . 298 Research Needs . 300 Multilevel Antecedence and Outcomes of Motivation in and of Teams 301 Research Needs . 303 Boundary Conditions Affecting Motivational Phenomena in and of Teams . 305 Team Type . 305 Team Interdependence . 306 Team Developmental Stages. 307 Cultural Differences . 308 Conclusion . 310 References . 311
The bHLH transcription factors MYC3 and MYC4 are targets of JAZ repressors and act additively with MYC2 in the activation of JA responses

Title: The Arabidopsis bHLH transcription factors MYC3 and MYC4 are targets of JAZ repressors and act additively with MYC2 in the activation of jasmonate responses. Authors: Fernández-Calvo P, Chini A, Fernández-Barbero G, Chico JM, Gimenez-Ibanez S, Geerinck J, Eeckhout D, Schweizer F, Godoy M, Franco-Zorrilla JM, Pauwels L, Witters E, Puga MI, Paz-Ares J, Goossens A, Reymond P, De Jaeger G, Solano R Journal: The Plant cell Year: 2011 Feb Issue: 23 Volume: 2 Pages: 701-15 DOI: 10.1105/tpc.110. 080788
Regulation of virulence-related genes by RNA and RNA-interacting proteins in bacteria

9 ZUSAMMENFASSUNG . 10 CHAPTER ONE: . 12 REGULATION OF STREPTOLYSIN S EXPRESSION BY A SMALL RNA AND RNASE Y IN STREPTOCOCCUS PYOGENES . 12 Regulatory RNAs in bacteria . 12 Riboswitches . 13 Discovery of riboswitches and ligand identification . 14 Streptococcus pyogenes . 15 Hemolysins in Streptococcus pyogenes . 16 Results . 23 RNase Y is involved in the processing of sagA transcript . 23 RNase Y regulates sagA mRNA expression . 26 RNase Y deletion affects hemolysis in ML but not in ES growth phase . 29 Truncations of sagA 5′ UTR affect sagA expression levels . 29 Structure changes in truncations might inhibit sagA expression . 33 Exposure to metabolite mixes affect the sagA 5′ UTR structure . 35 High-throughput method for riboswitch ligand identification . 40 Analysis of predicted riboswitches in S. pyogenes . 43 Discussion . 47 Materials and Methods . 52 Bacterial strains and growth conditions . 57 Bacterial transformation . 57 RNA extraction . 58 Polyacrylamide Northern blot analysis . 58 Rifampicin assay . 59 Transcriptional luciferase reporter expression . 59 Hemolysis assay . 60 qRT-PCR . 60 In vitro transcription . 61 Labelling and purification . 61
Regulatory Reform, Multiple Credit Ratings and the Quality of the Corporate Information Environment

This paper examines the change in the regulatory use of multiple credit ratings after the DoddFrank Act (Dodd-Frank). We find that post Dodd-Frank reform firms are less likely to demand a third rating, which is typically provided by Fitch. These ratings become less informative with a much weaker market impact on credit spreads for firms on opposite sides of the high yield (HY) investment grade (IG) boundary. Moreover, firms with reduced external monitoring from a third rating agency systematically manage their earnings more and have higher cash flow and sales volatilities post Dodd-Frank. Overall, the results shed light on the unintended consequences of Dodd-Frank on harming competition within the ratings industry and the quality of the corporate information environment.
EFFECT OF SOME HERBS AS FEED ADDITIVES ON PERFORMANCE, DIGESTIBILITY, CARCASS CHARACTERISTICS AND BLOOD PARAMETERS OF BROILERS

Two hundreds and sixteen one-day-old Coob-500 chicks were fed various diets for 6-weeks period and were equally divided into 6 treatment groups of 36 birds each, (3 replicates per group, of 12 birds each), using a completely randomized design, for 42 days. The diets included a control diet (without any additives) while the other five diets contained sweet basil (Ocimum basilicum L), fennel (Foeniculum vulgare),cinnamon (Cinnamomum Zeylanicum), oregano (Origanum vulgare L.) and there blend at 1% level as feed additives (10 g/kg feed). The results revealed that herb mixture treatment birds significantly increased the live body weight by 9% followed by the oregano treatment by 4.9% then the fennel treatment by 2.8% compared to the control group. However, the dietary herbs significantly improved the feed conversion ratio for Basil and Fennel treatments by the same value 5.6%, Cinnamon by 6.2, Oregano by 7.7 and for mixture treatments by 9.2% compared to the control group. Basil significantly decreased the abdominal fat by 53% and the liver weight by 7% compared to the control group. The mixture and oregano treatments significantly decreased the gizzard weight by 35.3% and 34.2% respectively, compared to the control group. Basil significantly decreased the total blood serum cholesterol by 17.2 % compared to the control group. The fennel and oregano significantly increased the A/G ratio at the same value by 29% compared to the control group. Cinnamon significantly improved the CP digestibility by 3.15 % compared to the control group. It can be concluded that the mixture of basil, fennel, cinnamon and oregano at the level of 1% significantly increased most growth performance parameters followed by oregano, cinnamon, basil and fennel.
A Validated Method for the Determination of Firocoxib in Equine Tissues

A new reversed-phase High Performance Liquid Chromatography (HPLC) method was developed and validated for the determination of firocoxib in equine tissue. Firocoxib was detected by ultraviolet detection at 290nm after undergoing a liquid extraction using ethyl acetate: hexane (40:60) and separation on a Sunfire C18 column. The mobile phase consisted of water with 0.025% trifluoroacetic acid and acetonitrile (50:50), with a flow rate 1.1 mL/min. A concentration range of 5-1500ng/gm produced a linear curve with r2>0.99. The lower limit of quantification was 5ng/gm. The intra and inter assay variability was <10% and the average recovery was 97%.
Bone height changes around hybrid implants in three implant retained mandibular Overdentures

Objective: The purpose of this RCL was to evaluate bone height changes around hybrid implants in three implant- retained mandibular overdenture with locator attachment.Materials & Methods: Ten completely edentulous male patients were enrolled in this study. Preoperative Cone beam computed tomography (CBCT) had been made to evaluate bone height & density in areas for implant installation. Patients had received three hybrid implants installed in midline & mandibular canine areas following flapless technique. Implants were early loaded; two weeks after implant installation. Overdentures were functionally fitted onto the locator attachment of the hybrid implants by direct pick-up technique.Evaluation: Bone height changes were evaluated with the aid of CBCT at the time of implants’ loading, six months and twelve months later. Mesial & distal crestal bone heights were calculated from reconstructed corrected sagittal views.Results: The results had revealed that there was no significant difference in peri-implant bone level throughout the follow-up periods on comparing the three implant sites. However, there was slightly higher bone resorption around the distal implants than the midline ones.Conclusions Three implant retained overdentures with locator attachments may preserve peri-implant bone in the anterior mandibular area. Midline implant in three implant overdentures may not be subjected to more stresses than the two distal implants
Effect of Zolpidem in the Aftermath of Traumatic Brain Injury: An MEG Study

In the past two decades, many studies have shown the paradoxical efficacy of zolpidem, a hypnotic used to induce sleep, in transiently alleviating various disorders of consciousness such as traumatic brain injury (TBI), dystonia, and Parkinson's disease. The mechanism of action of this effect of zolpidem is of great research interest. In this case study, we use magnetoencephalography (MEG) to investigate a fully conscious, ex-coma patient who suffered from neurological difficulties for a few years due to traumatic brain injury. For a few years after injury, the patient was under medication with zolpidem that drastically improved his symptoms. MEG recordings taken before and after zolpidem showed a reduction in power in the theta-alpha (4–12 Hz) and lower beta (15–20 Hz) frequency bands. An increase in power after zolpidem intake was found in the higher beta/lower gamma (20–43 Hz) frequency band. Source level functional connectivity measured using weighted-phase lag index showed changes after zolpidem intake. Stronger connectivity between left frontal and temporal brain regions was observed. We report that zolpidem induces a change in MEG resting power and functional connectivity in the patient. MEG is an informative and sensitive tool to detect changes in brain activity for TBI.
The Development of Free Inquiry Lab-Based Students’ Worksheet to Increase the Dimension in Science Literacy Process

This research aimed at 1) developing and producing feasible free inquiry lab-based students’ worksheet to increase the dimension in students’ science literacy process and 2) examining the effectivity of free inquiry lab-based students’ worksheet in increasing the dimension in students’ science literacy process. This research was conducted using research and development method. The students of XI MIPA SMA Kristen 1 Salatiga were the subject of this research. This research was conducted in the first semester of 2018-2019 academic year. The validation questionnaire and students’ response, the observation sheet of dimension process and learning model implementation, and science literacy question sheet were the research instrument covered in this research. The hypothesis test was conducted using paired-sample t-test. The result of this research revealed that 1) the developed free inquiry lab-based students’ worksheet was feasible based on the assessment result from the professional validator with the average 80.19% and the students’ response was very good towards the worksheet with the assessment average 82.49%. 2) The free-inquiry lab students’ worksheet was effective in increasing students’ dimension in science literacy process in plant tissue topic, which was supported with the average of students’ dimension of science literacy process 87.71% (very good) and the students’ N-Gain was 0.7 (very good). It was proved by the paired samples t-test statistic test with the result 0.00 < 0,05, therefore H0 was rejected, or in the other words, the free inquiry lab-based students’ worksheet was effective in increasing the dimension in science literacy process.
Critical Thinking Dispositions and Problem Solving Abilities among Nursing Students

Background: Critical thinking has now been accepted as the fundamental component of every education system. Aim: This study aimed to assess the relationship between critical thinking dispositions and Problem solving abilities among Nursing students. Design: A descriptive cross sectional correlational research design was used. Setting: The study was conducted at faculty of nursing El-fayoum University. Subjects: Included 434 nursing students. Tool of data collection: Data were collected by using two tools : A california critical thinking disposition inventory scale and problem solving questionnaire. Results: Highly mean score of the undergraduate nursing students (45.86) regarding truth seeking and low mean score regarding cognitive maturity (32.72). Highly mean score (49.25) regarding approach avoidance style and low mean score regarding personal control (12.98). Conclusion: There were statistically significant positive correlation between total critical thinking dispositions and total problem solving abilities among faculty nursing students. Recommendations: Faculties should provide student with orientation about importance of critical thinking and problem solving to meet the nursing challenges and future demands.
Nutritional value of fatty acids of the Neotropical freshwater fishes Prochilodus magdalenae, Pseudoplatystoma magdaleniatum and Ageneiosus pardalis ; Valor nutricional de los ácidos grasos de los peces de agua dulce neotropicales Prochilodus magdalenae, Pseudoplatystoma magdaleniatum y Ageneiosus 

This study aimed to determine the nutritional value of the fatty acids in the freshwater fish Prochilodus magdalenae, Pseudoplatystoma magdaleniatum and Ageneiosus pardalis during dry and wet Neotropical seasons with the view to generate useful information for nutrition and sustainable commercial exploitation. The analysis of fatty acids was performed by gas chromatography–mass spectrometry and the nutritional value was calculated using five estimators: n-6/n-3 ratio, unsaturation index (UI), atherogenicity index (AI), thrombogenicity index (TI) and ratio of hypocholesterolemic/hypercholesterolemic (h/H) fatty acids. A different number of fatty acids (P. magdaleniatum = 50, P. magdalenae = 41, and A. pardalis = 32) was identified for each species and the average abundance percentages were different in the two seasons (p < 0.05). Prochilodus magdalenae and P. magdaleniatum showed healthy n-6/n-3 ratios (1.04 and 2.72) in the different seasons. Although the three species showed low values of UI (0.37–0.63), the remaining nutritional indexes were within the healthy range (AI: 0.04–0.70, TI: 0.66–1.07, h/H: 0.80 – 24.40). Multivariate analysis showed similar healthy nutritional values for the species, with exception of P. magdaleniatum.
The Effect of Using a Teaching Strategy Based on the KWLH Learning Schedule to Gain the Concepts of Scientific Research Curricula among Princess Rahma University College Students

This study aimed to investigate the effect of using a teaching strategy based on the KWLH learning schedule to gain concepts of scientific research curricula among students of Princess Rahma University College. The study sample participants were intentionally chosen from students of Princess Rahma University College at Al-Balqa Applied University, who are enrolled in the research methodology course and its statistical methods. They were randomly assigned to two groups: an experimental group studied according to the teaching strategy based on the learning schedule KWLH, and a control group that studied according to the usual strategy. A test tool was implemented after verifying its validity and reliability, namely: Testing the concepts of scientific research methods. The study concluded that the teaching strategy based on the KWLH learning table was superior, and its percentage (16.24%) of the variance in the dependent variable was explained. The results showed that there was no statistically significant difference in the acquisition of the concepts of scientific research methods due to gender or the interaction between teaching strategy and gender. There was also a lack of a statistically significant difference in the acquisition of the concepts of scientific research methods due to the university cumulative average, compared to the presence of a statistically significant effect attributed to the interaction between the teaching strategy and the cumulative rate in the acquisition of the concepts of scientific research methods.
Adsorption of phosphate on Ca-carbon foam: batch experiments and model evaluation

Phosphate, which can cause eutrophication of the aquatic environment, can be effectively removed by an adsorption process using calcium-containing adsorbents. In this study, Ca-carbon foam was prepared by a simple method that entailed addition of Ca during the manufacturing process of carbon foam, and the phosphate removal characteristics of the prepared foam were analyzed using kinetic, equilibrium isotherm, and artificial neural network (ANN) models. The phosphate adsorption capacity decreased with an increase in the solution pH from 3.05 to 6.99. Furthermore, phosphate adsorption increased with increasing time, and the kinetic data were found to be well described by a pseudosecond-order model. The Freundlich isotherm provided the best fit of the equilibrium data, which indicates multilayer adsorption of phosphate on the Ca-carbon foam. The phosphate adsorption capacity as a function of three operational parameters—solution pH, initial phosphate concentration, and time—was well predicted by an ANN model (R2 > 0.993), and the optimal ANN for the process of phosphate adsorption on Ca-carbon foam had a 3–20–1 structure with 20 hidden layers. The solution pH was the most influential operational parameter out of all the examined parameters. The results of these analyses are expected to be useful in designing the process of phosphate adsorption from aqueous solutions.
Empowering Leadership and Employee Motivation, Behaviors, and Well-Being: Enabling or Burdening?

Empowering leadership has shown to be related to a variety of positive organizational outcomes, as well as positive individual outcomes for employees. However, some evidence suggests that there is also a burdening side to empowering leadership, whereby the increased autonomy and responsibility provided to employees can in fact be detrimental to firm and employee performance. The purpose of this study was to examine the effects of both enabling and burdening empowering leadership on employee motivation, extra-role behaviors, and well-being, while taking into account individual differences such as employee general self-efficacy and proactive personality. Drawing on the self-determination theory and social cognitive theory, this study proposes that empowering leadership will lead to positive behaviors, and reduced emotional exhaustion and turnover intention, through autonomous motivation, and that personality traits in subordinates will moderate these relationships. The data was collected using a short online questionnaire using employees (n = 267) from various firms across North America. Empowering leadership was positively related to autonomous motivation, and was also positively related to extra-role behavior, and negatively related to emotional exhaustion and turnover intention. Results showed support for the moderating effects of self-efficacy and proactive personality on extra-role behavior, emotional exhaustion and turnover intention. The findings of this study are relevant for the workforce, as leaders who are more aware of the effects of their leadership style will be better able to adjust their behavior accordingly in order to ensure their employees are performing at an optimal level, which will result in a more motivated and engaged workforce, and ultimately increased overall firm effectiveness
Evaluation of Glomerular Filtration Rate Estimating Formulas in Diabetic Patients with Chronic Kidney Disease

Objective: Measurement of glomerular filtration rate (GFR) is the best determinant in assessment of kidney function for diagnostic and therapeutic purposes. As extremely accurate methods of GFR measurement (i.e. Inulin clearance) are expensive and Time-consuming and due to limitations of the 24 hour urine collection method, some formula have been developed for the GFR measurement. Here we have compared the GFR calculated via CG or MDRD formulas and that measured by creatinine clearance in 24-hour urine collection method in diabetes patients with chronic kidney disease (CKD). Materials and Methods: This study was performed on 75 diabetes patients with stage 3 or 4 CKD (15-19 ml/min/1.73m) in the nephrology clinics of the Yazd medical university. The GFR was measured via CG and MDRD formula and also via creatinine clearance in 24-hour urine collection method. Correlation test and Bland altman plot was utilized to check for the relationship between creatinine clearance and the GFR. Results: Results show a significant correlation of the GFR calculated via creatinine clearance in 24-hour urine collection with GFR calculated via CG (r= 0.75) and with MDRD (r=0.70) formulas. This correlation was even increased when serum levels of creatinine was >1.5 mg/dL or in patients with stage 4 CKD. Comparison of the differences between GFR calculated via CG or MDRD formulas and creatinine clearance in 24-hour urine collection method using Bland altman showed a lower bias (CG: 17.76; MDRD: 10.64 ml/min/1.73 m) and narrower limits of agreement (MDRD: -11.33 – 32.62, CG: -4.68 – 40.20) to the creatinine clearance in 24-hour urine collection for the MDRD formula compared to that for the CG formula. Conclusion: CG and MDRD correlate well with creatinine clearance in 24-hour urine collection, while MDRD is more accurate in diabetes patients with stage 3 or 4 CKD.