Miracle-dz/UniFAR-FTUs huggingface dataset:
RMHP_A_314487 2465..2474

1Department of Trauma Surgery, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan; 2Department of Plastic Surgery, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan Background: The Geriatric Nutritional Risk Index (GNRI) is a simple and objective screening tool for clinicians to screen patients’ nutritional status based on serum albumin level and their weight and height. The original study had divided patients based on GNRI into quartiles of nutritional risk for death: a no-risk group (GNRI >98), a low-risk group (GNRI 92–98), a moderate-risk group (GNRI 82 to <92), and a major-risk group (GNRI <82). Given that the patients generally sustained traumatic brain injury (TBI) in an acute condition, the study aimed to explore whether GNRI presents a prognostic value for the mortality outcome of these patients. Methods: From January 1, 2009, to December 31, 2019, 581 elderly patients with moderate to severe TBI, which was defined as sustaining a head Abbreviated Injury Scale ≥3, was included in the study population. The collected data included age, sex, body mass index, serum albumin levels at admission, preexisting comorbidities, Glasgow Coma Scale, and Injury Severity Score. The primary outcome in the comparison was in-hospital mortality. Results: Multivariate logistic regression analysis revealed that GNRI, ESRD, and ISS were significant independent risk factors for mortality in patients with moderate to severe TBI. When subgrouping the study population into four nutritional risk categories according to the quartile deviation as Q1 (GNRI <85, n = 145), Q2 (GNRI 85 to <93.8 n = 145), Q3 (GNRI 93.8 to 103, n = 145), and Q4 (GNRI >103, n = 146), Q1 patients had a significantly longer LOS in hospital (25.2 days vs 18.6 days, respectively; p = 0.004) and higher mortality rate (28.3% vs 11.7%, respectively; p < 0.001) than Q4 patients. The mortality rate was significantly higher in Q1 patients than in Q4 patients (OR, 2.8; 95% CI, 1.14–6.78; p = 0.021). Conclusion: This study revealed that the GNRI is a significant independent risk factor and a promising simple assessment tool for mortality in elderly patients with moderate to severe TBI.
Are Volatile Organic Compounds Accurate Markers in the Assessment of Colorectal Cancer and Inflammatory Bowel Diseases ?

Colorectal cancer (CRC) is one of the leading causes of cancer‐related death in the Western world. Early detection decreases incidence and mortality. Screening programs based on fecal occult blood testing help identify patients requiring endoscopic examination, but accuracy is far from op‐ timal. Among the alternative strategies, volatile organic compounds (VOCs) represent novel poten‐ tially useful biomarkers of colorectal cancer. They also represent a promising tool for the screening of both intestinal inflammation and related CRC. The review is focused on the diagnostic potential of VOCs in sporadic CRC and in inflammatory bowel diseases (IBD), which increase the risk of CRC, analyzing future clinical applications. Despite limitations related to inadequate strength of evidence, differing analytical platforms identify different VOCs, and this unconventional approach for diagnosing colorectal cancer is promising. Some VOC profiles, besides identifying inflamma‐ tion, seem disease‐specific in inflammatory bowel diseases. Thus, breath, urine, and fecal VOCs provide a new and promising clinical approach to differential diagnosis, evaluation of the inflam‐ matory status, and possibly the assessment of treatment efficacy in IBD. Conversely, specific VOC patterns correlating inflammatory bowel disease and cancer risk are still lacking, and studies fo‐ cused on this issue are strongly encouraged. No prospective studies have assessed the risk of CRC development by using VOCs in samples collected before the onset of disease, both in the general population and in patients with IBD.
OSTEOPOROSIS IN CASES OF PEPTIC ULCER DISEASE

Objective. To determine the frequency of osteoporosis in patients with peptic ulcer disease. Methods; It was a descriptive, cross sectional study that was conducted at different centers of Sargodha and Lahore from January 2019 to September 2019. In the present study the cases of age 18 years or more diagnosed with peptic ulcer disease on history and then confirmed on upper GI endoscopy were included. These cases were then assessed on DEXA scan and osteoporosis was labelled as yes where there was score of less than 2.5. Results; In this study there were total 60 cases out of which 28 were males and 32 females. The mean age was 43.23±8.13 years. The mean duration of PUD was 3.2±0.31 years and mean T score was 1.2±0.8. Osteoporosis was seen in 4 (6.67%) of cases. Osteoporosis was more seen in females affecting 03 (9.38%) cases of their respective groups (p= 0.02). There was no significant difference in terms of duration of PUD with osteoporosis (p= 0.86). Conclusion: Osteoporosis is recently studied complication of peptic ulcer disease and is not very common, but still prevalent.
OPTH_A_271944 3261..3270

1Queen Victoria Hospital, East Grinstead, UK; 2Research Institute of Ophthalmology, Giza, Egypt; 3Maidstone and Tunbridge Wells Hospitals, Tunbridge Wells, UK Background: Visual recovery following macula involving rhegmatogenous retinal detachment remains poorly understood. The aim of this work is to correlate the functional and the anatomical changes in retinal vasculature in the foveal avascular zone using optical coherence tomography angiography (OCTA) after successful retinal reattachment repair and correlate this data with retinal thickness and post-operative visual recovery. Methods: A prospective, comparative observational study of 28 eyes of 14 patients with 14 eyes undergoing macula off retinal detachment repair with pars plana vitrectomy, endo-laser and silicone oil-based tamponade compared with 14 fellow healthy eyes at 1, 6 and 12 weeks post-operative period. The study was conducted at the Research Institute of Ophthalmology, Giza, Egypt between February 2018 and August 2018. Results: The foveal avascular zone (FAZ) area in the patients group was not significantly different compared to the control group and was found to be negatively correlated with the central retinal thickness in both the study and control group. The superficial capillary plexus (SCP) area at the FAZ was significantly larger than the deep capillary plexus (DCP) area at the FAZ in both the study and control group over the follow-up period. The DCP area at the FAZ was significantly larger at the 3rd follow-up than the 1st follow-up. The SCP FAZ area was significantly larger than the DCP FAZ area in both the study and control group over the follow-up period. BCVA was found to be negatively correlated to the retinal thickness of the temporal 3 mm paracentral quadrant with no correlation with central foveal thickness (CFT) and the FAZ area. Conclusion: Optical coherence tomography (OCT) and OCTA are valuable noninvasive imaging tools to monitor and predict the structural changes at the foveal avascular zone during the recovery phase after successful retinal reattachment involving macula.
NSS_A_305850 1167..1178

1Department of Pulmonology, Regional Hospital of Lugano (EOC), Lugano, 6900, Switzerland; 2Respiratory Function and Sleep Unit – Istituti Clinici Scientifici Maugeri IRCCS, Pavia, Italy; 3Exercise Medicine Unit, Istituto Auxologico Italiano, MIlan, 20133, Italy; 4University of Milan, BIOMETRA Department, Milan, Italy; 5Sleep and Epilepsy Center, Neurocenter of the Southern Switzerland, Regional Hospital (EOC) of Lugano, Lugano, Switzerland; 6Faculty of Biomedical Sciences, Università della Svizzera Italiana, Lugano, Switzerland; 7Department of Neurology, University Hospital, Inselspital, Bern, Switzerland; 8Department APSI, University of Geneva, Geneva, Switzerland; 9Department of Molecular and Translational Medicine, University of Brescia, Brescia, Italy; 10Department of Biomedical Sciences for Health, Università degli Studi di Milano, Milan, Italy; 11IRCCS Istituto Ortopedico Galeazzi, Milan, Italy; 12Stroke Center EOC, Department of Neurology, Neurocenter of Southern Switzerland Regional Hospital (EOC) of Lugano, Lugano, Switzerland
COMPARATIVE EVALUATION OF INTRAVENOUS TRANEXAMIC ACID AND HEMOCOAGULASE TO PREVENT BLOOD LOSS IN MAJOR ORTHOPAEDIC LOWER LIMB SURGERY

Introduction: Lower limb orthopaedic surgeries can lead to signicant intra-operative blood loss. Numerous techniques have been tried to reduce this blood loss. One of the two most common pharmacological agents used for this purpose in tranexamic acid and haemcoagulase. Both are known to decrease blood loss in lower limb orthopaedic surgeries. We conducted this study to compare their effectiveness which will further help clinicians to make more informed decisions. Material and methods: All the patients undergoing lower limb orthopaedic surgery between 01, June 2018 and 01, May 2019 were made part of this study. They were randomly allocated into tranexamic acid (T) group and haemcoagulase (H) group. Many parameters including blood loss were noted among both the groups and compared against each other. Results: The two groups did not had any statistical difference in terms of haemodynamic parameters but there was signicantly lower blood loss in H group compared to T group. There was no signicant difference in terms of fall in haemoglobin and haematocrit in both groups. Conclusion: Our statistical analysis of the data showed that there was signicant difference in terms of blood loss among both the groups with Hemocoagulase group having signicantly lower blood loss compared to tranexamic acid group.
THE SUPPLEMENTATION OF CREATINE, MALTODEXTRIN AND LACTATE PRODUCTION DURING SPORT

The aim of this study was to examine the metabolism of lactate. During high intensity exercise, the largest tract of ATP supply are the breakdown of creatine phosphate and degradation of muscle glycogen to lactic acid. Thus, reduction of glycogen and creatine phosphate contribute to the decrease in the anaerobic energy production and exercício. A fatigue performance is a decrease in muscle strength to maintain the power generation and the rate of relaxation, inducing alterations in the contractile characteristics of muscle and changes in electrical properties that generate malfunctions in the human neuromuscular system. Fatigue is extensively researched, but the exact mechanisms that lead to the changes it causes are still unclear. However, this fatigue is followed by a number of physiological and metabolic changes. It is concluded that blood lactate once again proves to be the best option for control of training. Moreover, the reduction of lactate demonstrates the use of smaller and larger glycolytic ATPCP system via providing better performance.
The Site of Leishmania major Infection Determines Disease Severity and Immune Responses

Inbred strains of mice infected with Leishmania major have been classified as genetically resistant or susceptible on the basis of their ability to cure their lesions, the parasite burden in the draining lymph nodes, and their type of T helper cell immune responses to the parasite. Using the intradermal infection at the base of the tail and the ear pinna, we compared for the first time the above-mentioned parameters in six strains of mice infected with metacyclic promastigotes, and we show that the severity of disease depends greatly on the site of infection. Although the well-documented pattern of disease susceptibility of BALB/c and C57BL/6 mice described for the footpad and base-of-the-tail models of leishmaniasis were confirmed, C3H/HeN and DBA/2 mice, which are intermediate and susceptible, respectively, in the tail and other models, were resistant to ear infection. Moreover, in the CBA/H, C3H/HeN, C57BL/6J, and DBA/2 mouse strains, there was little correlation between the pattern of cytokines produced and the disease phenotype observed at the ear and tail sites. We conclude that the definition of susceptibility and the immune mechanisms leading to susceptibility or resistance to infection may differ substantially depending on the route of infection.
Reference Point Adaptation and Disposition Effect: Evidence from Institutional Trading

Using a large proprietary database of institutional trades, we investigate whether, and to what extent, the dynamic adaptation of reference point translates into variations in the disposition effect, and establish three key results. First, the propensity to realize losses declines sharply with the magnitude of prior losses due to insufficient adaptation of reference point. Second, recent adverse information accelerates investors’ adaptation to price depreciation and increases investors’ willingness to realize losses. Finally, a priori of losing money in highly speculative investments decreases investors’ aversion to realize losses. Collectively, the findings suggest that both prior outcomes and recent expectations contribute to the reference point adaptation and the variations in disposition effect.
PREVALENCE OF CONGENITAL HYPOTHYROIDISM IN NEONATES IN SAUDI ARABIA

Objectives: To determine the various clinical presentations of and abnormalities associated with congenital hypothyroidism among children diagnosed in Saudi Arabia. Methods: A retrospective, descriptive study of congenital hypothyroidism and associated abnormalities was conducted in Saudi Arabia from January 2015 to October 2018 and included 173 children aged 0 to 12 months. Data were obtained by reviewing medical records and laboratory results via the hospital’s electronic system. Results were analyzed using descriptive statistics. Results: Of the 173 diagnosed cases; primary hypothyroidism was most common (95% of cases), while secondary hypothyroidism was diagnosed in 5% of cases. Of all cases diagnosed via the neonatal screening program, 57% were asymptomatic at the time of diagnosis and 43% were symptomatic. Prolonged jaundice (79%) was the most common clinical presentation. Other signs were constipation (7%), hypotonia (6%), goiter (4%), macroglossia (3%), and facial puffiness (1%). Associated congenital anomalies were found in 13% of cases. Conclusion: The findings confirm the importance of the neonatal thyroid-screening program, as 57% of diagnosed children were not symptomatic at diagnosis. Pediatricians should be aware of the various clinical presentations of congenital hypothyroidism, particularly prolonged neonatal jaundice.
Investigating Hydrogen-Based Non-Conventional Storage for PV Power in Eco-Energetic Optimization of a Multi-Energy System

Through the integration of multiple energy carriers with related technologies, multienergy systems (MES) can exploit the synergies coming from their interplay for several benefits towards decarbonization. In such a context, inclusion of Power-to-X technologies in periods of excess renewable electricity supply, removes the need for curtailment of renewable electricity generation. In order to achieve the environmental benefits of MES without neglecting their economic feasibility, the optimal design problem is as crucial as challenging and requires the adoption of a multi-objective approach. This paper extends the results of a previous work, by investigating hydrogen-based nonconventional storage for PV power in the eco-energetic optimization of an MES. The system under study consists of a reversible fuel cell (r-SOC), photovoltaic (PV), electric heat pump, absorption chiller and thermal storage, and allows satisfying the multi-energy needs of a residential end-user. A multi-objective linear problem is established to find the optimal MES configuration including the sizes of the involved technologies with the goal of reducing the total annual cost and the fossil primary energy input. Simulation results are compared with those obtained in previous work with a conventional nanogrid where a combined heat and power (CHP) system with gas-fired internal combustion engine and a battery were present instead of an r-SOC. The optimized configuration of the non-conventional nanogrid allows achieving a maximum primary energy reduction amounting to 66.3%, compared to the conventional nanogrid. In the face of the environmental benefits, the nonconventional nanogrid leads to an increase in total annual costs, which, compared to the conventional nanogrid, is in the range of 41–65%.
ACELL May 47/5

Hou, Ping, Anke Di, Ping Huang, Charlotte B. Hansen, and Deborah J. Nelson. Impermeability of the GIRK2 weaver channel to divalent cations. Am J Physiol Cell Physiol 278: C1038–C1046, 2000. —A single amino acid mutation (G156S) in the putative pore-forming region of the G proteinsensitive, inwardly rectifying K1 channel subunit, GIRK2, renders the conductance constitutively active and nonselective for monovalent cations. The mutant channel subunit (GIRK2wv) causes the pleiotropic weaver disease in mice, which is characterized by the selective vulnerability of cerebellar granule cells and Purkinje cells, as well as dopaminergic neurons in the mesencephalon, to cell death. It has been proposed that divalent cation permeability through constitutively active GIRK2wv channels contributes to a rise in internal calcium in the GIRK2wv-expressing neurons, eventually leading to cell death. We carried out comparative studies of recombinant GIRK2wv channels expressed in Xenopus oocytes and COS-7 cells to determine the magnitude and relative permeability of the GIRK2wv conductance to Ca21. Data from these studies demonstrate that the properties of the expressed current differ in the two systems and that when recombinant GIRK2wv is expressed in mammalian cells it is impermeable to Ca21.
Hydrodynamic analysis of a semi-submersible type floating wind turbine

Submission November 10, 2014 KEY DATES Manuscript for Review January 20, 2015 Final Papers Due March 24, 2015 Suggested Technical Topics: Offshore Wind Energy and Resources: Fixed/Floating Structures, Foundation Wind Turbines: Test, Measurements, Control, Simulation, Design Optimization Aero-, Hydroand Geo-mechanics, Loads and Structural Responses, CFD Ocean Energy and Resources; Waves, Tidal, OTEC and Bioenergy Environmental Modeling and Impact Assessment: Coastal, Marine, Arctic & Antarctic Symposium Organizing Committee: Prof. F. Dias, University College Dublin, Ireland Mr. P. Valverde, EDP, Lisboa, Portugal Dr. T. Fischer, Rambøll Energy, Germany Dr. S. Herion, Karlsruhe Institute of Technology, Germany Dr. Seok W. Hong, KRISO, Korea Prof. B. S. Hyun, Korea Maritime and Ocean University, Korea Dr. J. P. Kofoed, Aalborg University, Denmark Profs. I. Langen, J.P. Liyanage, University of Stavanger, Norway Mr. D. Matha, Universität Stuttgart, Germany Prof. M. Muskulus, NTNU, Norway Prof. S. Nagata, Saga University, IOES, Japan Prof. K. Otsuka, Osaka Prefecture University, Japan Prof. A.J.N.A. Sarmento, Technical University IST, Portugal Prof. John D. Sørensen, Aalborg University & DTU Wind Energy, Denmark Mr. F. Vorpahl, Fraunhofer IWES, Germany Prof. Jin S. Chung, ISOPE, USA Interested authors should send abstracts to one of the organizing committee members or submit online at: http://www.isope. org/call4papers/2015/HowToSubmitAbstractOnline.htm. The abstracts MUST include the contact author’s postal address, telephone and fax numbers, and e-mail address to facilitate communications. First Call For Papers www.isope. org for updates
NEW APPROACHES IN DECEPTION DETECTION II. ACTIVE INTERVIEWING STRATEGIES AND CONTEXTUAL INFORMATION

2015a) we explained that, historically, research into deception detection has been based on the premise that people show certain revealing behavioural indicators when deceiving. These indicators were assumed to appear automatically and to be difficult to control. However, recent meta-analytical research has shown that this assumption is incorrect: the behavioural indicators of deception are scant, poorly diagnostic and changing. Consequently, the accuracy rates of individuals in judging the veracity of others are low and the increase due to training programs is limited (see Masip & Herrero, 2015a). This finding has caused a shift in deception detection research, which has forked into two different approaches: (a) the design of active interviewing techniques aimed at generating and/or maximising behavioural differences between truth-tellers and liars, and (b) the recognition of the importance of contextual information in judging veracity. The purpose of this article is to describe these two approaches.
Voicing job satisfaction and dissatisfaction through Twitter: Employees’ use of cyberspace

This article adopts a work orientations perspective to consider how, through the medium of Twitter, employees voice the things they love and hate about their jobs. Using 817,235 tweets posted by 650,958 users in the calendar year 2014, the findings provide new insights into both the employee voice and job satisfaction/dissatisfaction literatures as well as an enhanced understanding of the nature of the employment relationship. First, our findings indicate that Twitter, in its expression of very personal and individualistic needs, might be considered a new form of employee voice. Second, Twitter captures the positive, the negative and the ambivalence in the notion of job satisfaction. Third, the description of the methodology used to access and analyse Twitter data illustrates how new methodological approaches, particularly those embedded within computer science, may be of value to social scientists in their analysis of 'Big Data'.
Emotional Competence Among Day Scholars and Hostellers

The present research aims to study the emotional competence among day scholars and hostellers. Emotional competence is the efficacy of an individual to deal with emotional situations effectively. The word competence refers to mastery over some skill which indicates that competence can develop over time. Saarni proposes that the social environment influences the process of developing emotional competence. This research is aimed at studying the effect the living status has on emotional competence. In the present study, the Emotional Competence scale by Bhardwaj and Sharma (1998) was used which consists of 30 items measuring five domains and the score ranges from 30 to 150. A total of 123 samples was collected for this purpose. For analysis two-way ANOVA was used. The result indicated that there is no effect of living status on emotional competence, however, there was a significant effect of gender on emotional competence. There was no significant interaction effect of gender and living status on emotional competence.
A SIMPLE COLOURIMETRIC ASSAY FOR NONINVASIVE DIAGNOSIS OF LIVER FIBROSIS IN CHRONIC HEPATITIS B PATIENTS

Background: Chronic hepatitis B virus run the risk of developing liver fibrosis, cirrhosis and in later life hepatocellular carcinoma. Aim: The aim is to test the diagnostic power of N-acetyl-β-D-glucosaminidase (NAG) in assessing liver fibrosis and its ability to improve those of AAR, FIB4 and GUCI scores in the previous patients. Methods: Blood samples for complete blood count and serum for N-acetyl-β-D-glucosaminidase (NAG) assays, liver function tests, HBV DNA and HBV markers evaluation were taken (n=71, F0 F4 according to liver stiffness calculated by transient elastography). The numerical values of the six scores were quantized and correlated with that of NAG. Results: NAG can efficiently differentiate patients with non-significant (F0, F1) from those with significant fibrosis (F2 –F4); sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) of 81, 91, 90, 81, respectively with AUC of 0.900. The additions of the results of NAG to those of the previous scores greatly enhance their AUCs and their diagnostic power in the majority of cases. Conclusions: NAG, itself, cannot only help in assessing hepatic fibrosis but can also enhance the diagnostic power of the tested scores to discriminate the fibrotic stages of HBV chronically infected Egyptian patients.