Glucocorticoid induced osteoporosis and mechanisms of intervention

s Sato AY, Cregor M, Condon KW, Plotkin LI, Bellido T. 2016. Pyk2 deficiency 2016 protects from glucocorticoid-induced bone resorption and osteoblast and osteocyte apoptosis, but not from the decrease in bone formation. J Bone Miner Res. 31 (Suppl. 1). Oral Presentation and ASBMR Young Investigator Travel Grant Award. Sato AY, Cregor M, Tzeggai J, McAndrews K, Delgado-Calle J, Robling AG, 2015 Plotkin LI, Bellido T. 2015. Sost/sclerostin deficiency protects the murine skeleton from glucocorticoid-induced bone loss by inhibiting bone resorption. Orthopaedic Research Society (ORS) 45 Sun Valley Workshop. Alice L. Jee Award. Sato AY, Au E, Richardson D, Bivi N, Cregor M, McAndrews K, Davis HM, 2015 Zimmers T, Plotkin LI, Bellido T. 2015. Glucocorticoids induce bone and muscle atrophy by distinct mechanisms upstream of atrogin1 and MuRF1. J Bone Miner Res. 30 (Suppl. 1). Oral Presentation and ASBMR Young Investigator Award. Sato AY, Cregor M, Tzeggai J, McAndrews K, Delgado-Calle J, Robling AG, 2015 Plotkin LI, Bellido T. 2015. Sost/sclerostin deficiency protects the murine skeleton from glucocorticoid-induced bone loss by inhibiting bone resorption. J Bone Miner Res. 30 (Suppl. 1). Plenary Poster. Maycas M, McAndrews KA, Sato AY, Pellegrini GG, Brown DM, Allen MR, 2015 Plotkin LI, Esbrit P, Gortzar AR, Bellido T. 2015. PTHrP-derived peptides restore bone mass and strength in diabetic mice: additive effect of mechanical loading. J Bone Miner Res. 30 (Suppl. 1). Pellegrini GG, Cregor M, McAndrews K, Delgado-Calle J, Sato AY, Davis HM, 2015 Plotkin LI, Burr D, Weaver C, Bellido T. 2015. N Nrf2 mediates gender specific mechanisms on bone accrual and maintenance. J Bone Miner Res. 30 (Suppl. 1). Sato A, Plotkin LI, Bellido T. 2013. Prevention of glucocorticoid 2013 induced-apoptosis of osteoblasts and osteocytes by protecting against endoplasmic reticulum (ER) stress. J Bone Miner Res. 28 (Suppl. 1). Delgado-Calle J, Tu X, Sato A, Cregor M, McAndrews K, Plotkin LI, Bellido T. 2013 2013. PTH upregulates RANKL and MMP13 expression through direct actions on osteocytes, but MMP13 is derived from non-osteocytic cells. J Bone Miner Res. 28 (Suppl. 1). Plenary Poster. Bivi N, Olivos N, Sato A, Southern D, Bellido T. 2012. Glucocorticoids induce 2012 atrophy of bone andmuscle by FoxOand ATF4-dependent mechanisms. J Bone Miner Res. 27 (Suppl. 1). Hill K, Gallant M, Brown D, Sato A, Burr D. 2012. Raloxifene prevents skeletal 2012 fragility in adult female zucker diabetic sprague-dawley (ZDSD) rats. J Bone Miner Res. 27 (Suppl. 1). Bivi N, Olivos N, Sato A, Southern D, Bellido T. 2012 Atrophy is a common 2012 pathway activated by glucocorticoids in bone and muscle. IBMS Sun Valley Workshop: Musculoskeletal Biology. 42. Oral presentation. Sato A, Yaden B, Kline A, Krishnan V. 2010. Use of non-invasive MRI/MRS 2010 techniques to assess recovery in muscle tissue. Endocrine Reviews. 31 (Suppl. 1). Halladay D, Sato A, Ma Y, Shetler P, Bullock H, Krishnan V. 2010. Exploring 2010 the LRP5 SOST interacting surface to identify small molecule inhibitor of SOST Action. J Bone Miner Res. 25 (Suppl. 1). Professional Associations ASBMR, American Society for Bone and Mineral Research 2012-2017 Orthopaedic Research Society (ORS) 2015-2017 Golden Key International Honour Society 2016 Endocrine Society 2010-2011 Phi Beta Kappa 2010-2011 Psi Chi, International Honor Society in Psychology 2009-2011 Order of Omega, Leadership Honor Society 2008-2010 Employment & Positions DePauw University– Greencastle, IN 2010-2011 Undergraduate Teaching Assistant with Dr. K. S. Kinney, Professor of Biology Spent two semesters serving as the teaching assistant (T.A.) for Dr. K. S. Kinney’s Animal Physiology course involving instruction for course materials in T.A. led review sessions, basic laboratory techniques, and standard animal husbandry and handling skills. These efforts led to an unprecedented awarding of course credit. Eli Lilly and Company– Indianapolis, IN 2009-2010 Summer Replacement Student with Dr. G. Krishnan, Musculoskeletal DHT Spent two summers and a winter term with Dr. G. Krishnan researching muscle atrophy using MRS analyses of the gastrocnemius muscle and the canonical Wnt pathway using molecular and cell biology techniques. These efforts led to poster presentations at the annual conferences for the Endocrine Society 2010 and American Society for Bone and Mineral Research 2010 meetings. InfoSpherix Incorporated– Carmel, IN 2007-2008 Reservation Specialist Advised clients of risk management policies. Supervised part-time employees. Solved quality assurance concerns. Administered tech support for online division. Executed client billing and notification.