Miracle-dz/UniFAR-FTUs huggingface dataset:
Visual estimation of blood loss versus quantification of blood loss after vaginal birth using an innovative drape: a prospective study

Background: This study was done to compare the accuracy of visual estimation of blood loss (EBL) and quantitative assessment of blood loss (QBL, sum of volumetric and gravimetric assessment) against a reference standard i.e. calculated QBL (C-QBL) and also with each other after vaginal birth.Methods: Prospective observational cohort study conducted at Pt. JNM medical College Raipur, Chhattisgarh, India and involved 101 low risk women after vaginal birth. Women were allocated alternately to EBL or QBL group (volumetric component of measured blood loss was done with an innovative low cost drape prepared with a plastic apron at the point of care. Gravimetric component was measured by weight difference of the mops and pads before and after use). C-QBL was calculated for each case with a standard formula. Main outcome measure was comparing the correlation coefficient of EBL and QBL each with C-QBL.Results: The mean blood loss in 51 women of EBL group and 50 women of QBL group was 275.29 ml and 380 ml respectively. Pearson’s correlation coefficient (r) of EBL with C-QBL was 0.4984 (weak correlation) compared to that of QBL with C-QBL (r=0.9093, strong positive correlation). The error of underestimation by EBL compared to QBL was 28% (mean=104.71 ml p<0.0001). The relative risk (RR) of underestimating blood loss of >500 ml by EBL method was 5 (95% CI .605-41.3). Conclusions: Visual EBL should be replaced with QBL for measurement of postpartum blood loss. Using innovative under-buttock low cost drape greatly helps in routine QBL.
Phytochemical Screening and Toxicity Activities of Eleiodoxa conferta Plant Extracts

Researchers are actively exploring the locally available fruits that may use for therapeutic remedies. Eleiodoxa conferta is an underutilized Malaysian fruit. This study was conducted to examine bioactive compounds and toxicity activities of different parts of E. conferta using 100% ethanol, 50% ethanol, and water for extraction. Results showed that Ethanol (50% v/v) was the best extraction solvent. The highest and lowest yield shown in the flesh extract and seed extract at 39.247% and 4.89%, respectively. The peel of E. conferta always showed higher Total Phenolic Content (TPC) and Total Flavonoid Content (TFC) as compared to other parts of the plant. Phytochemical compounds such as flavonoids, phenol, tannin, to name a few, were abundantly present in most extractions. The toxicity screening revealed that the toxicity level was high in the seed part of E. conferta while low toxicity shown in the flesh of the fruit. Overall, this fruit is rich in bioactivities. Further studies can be done to uncover its true potential application, especially the application of those bioactive components as antimicrobial agents in preserving food.
Two-Stage Classification Method for MSI Status Prediction Based on Deep Learning Approach

Colorectal cancer is one of the most common cancers with a high mortality rate. The determination of microsatellite instability (MSI) status in resected cancer tissue is vital because it helps diagnose the related disease and determine the relevant treatment. This paper presents a two-stage classification method for predicting the MSI status based on a deep learning approach. The proposed pipeline includes the serial connection of the segmentation network and the classification network. In the first stage, the tumor area is segmented from the given pathological image using the Feature Pyramid Network (FPN). In the second stage, the segmented tumor is classified as MSI-L or MSI-H using Inception-Resnet-V2. We examined the performance of the proposed method using pathological images with 10× and 20× magnifications, in comparison with that of the conventional multiclass classification method where the tissue type is identified in one stage. The F1-score of the proposed method was higher than that of the conventional method at both 10× and 20× magnifications. Furthermore, we verified that the F1-score for 20× magnification was better than that for 10× magnification.
The Marketization of Rural Collective Construction Land in Northeastern China: The Mechanism Exploration

The transfer of rural collective construction land into the market (RCCL marketization) is an important starting point for breaking the urban–rural dual system, realizing the sustainable use of land resources and promoting the integrated development of urban and rural areas in China. This study aims to explore the decision-making of rural households in the marketization of rural collective construction land (RCCL) by constructing a two-stage (cognition-decision) theoretical framework. Based on the household survey data collected from the pilot areas in the three northeastern provinces in China, the structural equation modelling (SEM) has been applied. The main findings are as follows: (1) the four types of exogenous latent variables, including information dissemination, management of collective economic organizations (CEOs), family characteristics, and household head characteristics, are intermediary by household cognition, which then positively affect households’ behavior and decision-making. (2) among the factors affecting household cognition, the management of CEOs exhibits the most significant impact, followed by information dissemination, family characteristics, and household head characteristics. (3) the measurable variables, including participation rights, whether there are collective operating assets, education level, and whether members have social insurance, have significant effects on the four exogenous latent variables. (4) the understanding of income distribution policy has the greatest positive impact on household cognition, while risk perception has the opposite effect, indicating an obvious “risk aversion” tendency for rural households. The findings imply that the government should improve the existing RCCL market entry system from the aspects of strengthening collective economic organization construction, land value-added income sharing mechanism, and clarifying rural land property rights, so as to reduce farmers’ decision-making risks and enhance value perception. Overall, the research presented here contributes to investigating the theoretical mechanism of household decision-making and providing empirical evidence on how to improve the marketization of rural collective construction land in China.
Democracy, Autocracy, and Everything in Between: How Domestic Institutions Affect Environmental Protection

Abstract As major global challenges intensify in the twenty-first century, which domestic institutions will best enable countries to take decisive and positive action? This article explores this question in the realm of environmental policy. Scholars and practitioners have long argued that ‘democracy’ yields the best environmental outcomes, but others now maintain that ‘eco-authoritarianism’ may be the best way forward. The author unpacks the theoretical mechanisms behind these debates, and adds important nuance in making three arguments. First, the link between elections and eco-policy depends on what citizens want. Secondly, the relationship between civil liberties protections and environmentalism depends on which actors within society hold power. Finally, political constraints make environmental policy change – be it environmentally friendly or damaging – more difficult. The study empirically tests these arguments and finds strong support for the expectations regarding elections and civil liberties. There is only limited evidence that constraints stymie eco-policy change.
Service security breaches: the impact of comparative optimism

ABSTRACT The main purpose of this research is to examine the joint effects of error management, error locality, and individuals’ comparative optimism on consumers’ attitudes and intentions to spread negative word-of-mouth. To explore consumers’ reactions, a 2 (Error management: Yes vs. No) x 2 (Error locality: Focal vs. Competitor) x 2 (Comparative optimism: High vs. Low) experiment was employed. Results indicated that when the focal hotel is breached, individuals who are high on comparative optimism exhibit more positive attitudes and a lower level of intentions to spread negative word-of-mouth when error management is presented (vs. no error management). When a competitor is breached, people show similar levels of attitudes and behavioral intentions regardless of the conditions of error management. Findings of this research contribute to strategic planning and policymaking regarding information security.
Formulation Development, Characterization and In Vitro Antibacterial Activity Evaluation of Cefazolin Loaded Mesoporous Silica Nanoparticles

The main aims of this manuscript are to: i) investigate the high drug loading of cefazolin and its characterization, ii), demonstrate the bioactivity of the cefazolin particles in vitro on Staphylococcus aureus. From our results, it is observed that the cefazolin loading into MCM-41 particles is 34 wt %. Furthermore, particles showed the burst release of cefazolin at pH 6.8. At higher concentration, MCM-41 particles are comparatively more cytotoxic as compared to lower concentration. Finally, cefazolin loaded particles showed higher in vitro antibacterial activity against Staphylococcus aureus as compared to cefazolin only.
Students Critical-Creative Thinking Skill: A Multivariate Analysis of Experiments and Gender

Students’ ability to practice several thinking skills is one of the problems common in today’s learning. Therefore, this research aims to describe the improvement of students’ critical-creative thinking skills through a multivariate analysis of the experiment model and gender. The experiment models used in this research are the Multiple Skill Laboratory Activity Model (MSLAM) and Higher Order Thinking Laboratory (HOT Lab), with gender, considered as a factor influencing a successful learning process. Research method was a quasi-experiment with data obtained from 328 respondents from five different universities in Indonesia and analyzed using the multivariate tests. The results showed that the experiment model affected the learning outcomes more than genders. Furthermore, the Multiple Skill Laboratory Activity Module proved to improve students’ critical and creative thinking skills better than the Higher Order Thinking Laboratory. This study expected to provide a comparison in determining the types of suitable experiments for learning at colleges and schools.
Efficacy of certain herbicides on broad-leaved weeds in wheat crop (Triticum aestivum L.)

Field experiments were carried out at Mutobus District, Kafr El-Sheikh Governorate to evaluate the efficacy of AckocynilR (bromoxynil octanoate 32.75% EC) at 1.00 L. fed-1, Brominal WR (bromoxynil octanoate 24% EC) at 1.00 L. fed-1, DerbyR (florasulam 7.5 %+ flumetsulam 10%) at 30 ml fed. -1, IcopartR (pyraflufen-ethyl 2% SC) at 250 ml fed. -1 and SinalR (metosulam 10% SC) at 40 ml fed. -1 in comparison with handweeding twice (at 21 and 42) days after sowing and untreated check (weed free) during 2017/2018 and 2018/2019 seasons on broad-leaved weeds in wheat crop. Anagallis arvensis, Beta vulgaris, Cichorium pumpilum, Medicago sativa, Rumex dentatus and Sanchus oleraceus, were the predominant weed species during the both seasons, except, Anagallis arvensis, which was found in the second season only. All predominant weeds in the experimental field were identified as broadleaved weeds. Among predominant weed species, Beta vulgaris and Medicago sativa were the most predominant during 2017/2018 and 2018/2019 seasons. Results clearly indicated that all herbicidal treatments showed significant herbicidal activity against weeds compared to the control during the two examined seasons. Among the herbicides examined, AckocynilR and Brominal WR were the most options in controlling weeds as well as increasing yield components and grain yield in wheat crop than the other treatments.
Antidepressant-like effect of Cuminum cyminum essential oil on the forced swim and tail suspension tests in male mice

Background and aims: Several pharmacological and biological activities have been attributed to Cuminum cyminum L. (CC), including analgesic, antioxidant, anti-inflammatory, and anti-epileptic effects. In this regard, the present study evaluated the antidepressant-like effects of the CC essential oil (EO) on the forced swim test (FST) and tail suspension test (TST) in male mice. Materials and Methods: The gas chromatography-mass spectrometry (GC-MS) apparatus was used for detecting the chemical compounds of CC EO. In the present study, 72 male NMRI mice were randomly allocated to 12 groups (each containing 6 animals) including control or vehicle (10 mL/kg, i.p.), fluoxetine (20 mg/kg, i.p.), imipramine (30 mg/kg, i.p), and the CC EO (100, 200, and 300 mg/kg, i.p.). Then, several parameters were measured and recorded, including immobility time, swimming time, and climbing time in FST, along with immobility time in TST, respectively. Results: Cuminaldehyde followed by cymene, γ-terpinene, phenylglycol, 2-caren-10-al, 2-β-pinene, acoradiene, and cuminic acid were the major components of the CC EO. Based on the results, all doses of the CC, fluoxetine, and imipramine reduced immobility time in both FST (P<0.001) and TST (P<0.001). On the other hand, all doses of the CC and fluoxetine increased swimming time (P<0.001) although climbing time was only increased by 200 and 300 mg/kg of the EO (P<0.01 and P<0.001, respectively) and imipramine (P<0.001). Conclusion: Based on the findings of the present study, the components of the CC induced antidepressant-like activity similar to that of fluoxetine and imipramine in both tests. However, further studies are required to confirm the role of different active components and the exact mechanism of action.
Psychometric Properties and Prospective Predictive Utility of the Contrast Avoidance Questionnaires

Abstract. Recent theoretical research posits that a key factor in the development and maintenance of pathological worry is the avoidance of sudden emotional shifts. Recently two self-report instruments were developed to index this phenomenon (Contrast Avoidance Questionnaire – Worry [CAQ-W] and Contrast Avoidance Questionnaire – General Emotion [CAQ-GE]). This work employed a multi-study design to provide an independent evaluation of the latent structure of these measures; additionally, the validity and longitudinal predictive ability of the measures was examined. Findings of the factor analytic work support a two-factor solution for each of the questionnaires. These were defined as the following subscales: CAQ-W: Emotional Contrast; Negative Affect, and for the CAQ-GE: Avoidance; Discomfort. Test-retest reliability of the measure was strong and the identified subscales demonstrated differential predictive ability regarding future worry and depression. Results indicate that subscales related to the experience of negative affect rather than avoidance, display predictive utility of future symptoms. These findings are somewhat discrepant with extant literature on ecological momentary assessment (EMA) assessment of contrast avoidance indicating the need for refinement in the self-report measurement of this construct.
Identification of High Performance Solvents for the Sustainable Processing of Graphene

Nanomaterials have many advanced applications, from bio-medicine to flexible electronics to energy storage, and the broad interest in graphene-based materials and devices means that high annual tonnages will be required to meet this demand. However, manufacturing at the required scale remains unfeasible until economic and environmental obstacles are resolved. Liquid exfoliation of graphite is the preferred scalable method to prepare large quantities of good quality graphene, but only low concentrations are achieved and the solvents habitually employed are toxic. Furthermore, good dispersions of nanomaterials in organic solvents are crucial for the synthesis of many types of nanocomposites. To address the performance and safety issues of solvent use, a bespoke approach to solvent selection was developed and the renewable solvent Cyrene was identified as having excellent properties. Graphene dispersions in Cyrene were found to be an order of magnitude more concentrated than those achieved in N-methylpyrrolidinone (NMP). Key attributes to this success are optimum solvent polarity, and importantly a high viscosity. We report the role of viscosity as crucial for the creation of larger and less defective graphene flakes. These findings can equally be applied to the dispersion of other layered bi-dimensional materials, where alternative solvent options could be used as drop-in replacements for established processes without disruption or the need to use specialized equipment. Thus, the discovery of a benign yet high performance graphene processing solvent enhances the efficiency, sustainability and commercial potential of this ever-growing field, particularly in the area of bulk material processing for large volume applications.
The Effect of Alkaline Treatment on Mechanical Properties of Polylactic Acid Reinforced with Kenaf Fiber Mat Biocomposite

Kenaf fiber mat (KFM) reinforced polylactic acid (PLA) biocomposite have been developed by using film stacking and compression molding. In order to achieve the composite with good mechanical properties, the effect of processing parameters such as processing temperature and heating time on mechanical properties of PLA was studied. The optimum values of processing temperature and heating time on mechanical properties of PLA that were obtained were then being used to produce PLA/KFM biocomposite. PLA and kenaf fiber has distinct properties as natural fiber is hydrophilic whereas the polymer matrix is hydrophobic. In order to improve the fiber matrix adhesion, the KFM was chemically treated at different concentrations of NaOH for 3 hours at room temperature. Mechanical properties such as tensile and flexural strength, tensile and flexural modulus and elongation at break of untreated and alkali-treated PLA/KFM biocomposite were studied and compared. The obtained results showed that the alkali treatment have impact on the mechanical properties of PLA/KFM biocomposite. The study has demonstrated that the optimum alkali concentration was 4% NaOH concentration.
Detection and Prevalence of Canine Leptospirosis from Navsari District of South Gujarat, India

Aims: Leptospirosis is endemically prevalent in coastal area of south Gujarat. Generally, pets are vaccinated against Leptospira interrogans but whosoever left unvaccinated, are prone to infection. The present study was conducted to detect canine leptospirosis and its prevalence from south Gujarat. Place and Duration of Study: A total of 46 serum samples and 33 urine samples were collected from 56 dogs suspected of having leptospira infection. The study was done from September 2019 to May 2020. Original Research Article Desai et al.; MRJI, 30(9): 103-110, 2020; Article no.MRJI. 63957 104 Methodology: Serum samples were diagnosed by IgG based ImmunoComb solid phase dot ELISA test for antibody against genus specific Leptospira interrogans. Urine samples were visualized under dark field microscopy (DFM) following laboratory manual on leptospirosis of WHO. Sex and age of dogs were noted to find out the percent positivity and prevalence. Chi square test was applied to find out any significant difference among the age groups. Results: Out of 46 serum samples, 17 (36.95%) found positive by dot ELISA and out of 33 urine sample, 13 (39.39%) found positive by DFM. Sex wise prevalence found 42.10 percent (16/38) in Male while 55.55 percent (10/18) in female dogs. Age group wise prevalence was recorded 63.63 percent (07/11) in 1≤ 3 years group. 27.77 per cent (05/18) in > 3≤ 6 years group whereas, 51.85 percent (14/27) in > 6≤ 12 years group. Conclusion: Detection and prevalence of canine leptospirosis were studied first time from Gujarat. Overall 46.42 percent (26/56) dogs were diagnosed positive for canine leptospirosis. Dogs having age group of 1≤ 3 years found more susceptible. Prevalence was found more in female than male dogs.
Analysis and Functional Studies of the Gasotransmitters Hydrogen Sulfide and Nitric Oxide

v ACKNOWLEDGEMENTS . vi LIST OF TABLES . x LIST OF FIGURES . xi LIST OF APPENDICES . xiv LIST OF ABBREVIATIONS/SYMBOLS . xv CHAPTER 1: GENERAL INTRODUCTION . 1 1.1 Hydrogen Sulfide . 2 1.1.
Assessing policies to mitigate abandonment of shade-grown coffee production in forest systems amid low and uncertain prices

Abstract Low and highly variable prices plague the coffee market, generating concerns that coffee farmers producing in shade systems under natural forests, as in biodiversity hotspot Oaxaca, Mexico, will abandon production and contribute to deforestation and reduced ecosystem services. Using stakeholder information, we build a setting-informed model to analyze farmers' decisions to abandon shade-grown coffee production and their reactions to policy to reduce abandonment. Exploring price premiums for bird-friendly certified coffee, payments for ecosystem services, and price floors as policies, we find that once a farmer is on the path toward abandonment, it is difficult to reverse. However, implementing policies early that are low cost to farmers – price floors and no-cost certification programs – can stem abandonment. Considering the abandonment that policy avoids per dollar spent, price floors are the most cost-effective policy, yet governments prefer certification programs that push costs onto international coffee consumers who pay the price premium.
Histopathological study of cervical lesions: a hospital based study in teaching hospital Batticaloa, Sri Lanka

The uterine cervix is prone for infections and malignancies. The cervical cancer is fourth most common cancer in the world and second common female cancer in Sri Lanka. This hospital based retrospective study was done on 586 cervical specimens. This study was aimed for the histomorphology patterns of cervical lesions. Results; There were 10.2% malignant cases and 68.90% were non-neoplastic cervical specimens. Majority of the non- neoplastic cervical lesions were inflammation and polyp, constitute 37.2% and 17.7% of the total study samples. Majority of patients with cervical carcinoma (36.5%) presented with blood-stained, whitish per vaginal discharge and it is followed by (32.7%) abnormal uterine bleeding. The peak age incidence of cervical cancer was 50-59 years. Squamous cell carcinoma was by far the most common histological type accounting for 84.6%, followed by adenocarcinoma 11.5%. Squamous cell cervical carcinoma classified according to Broder’s grading system into well, moderately and poorly differentiated at the time of initial diagnosis and constituting cases as 20%, 71.1% and 8.9% respectively. The chronic nonspecific cervicitis was the most common inflammatory lesion constituting 86.2% of nonneoplastic cases. The main presenting complaints of blood-stained vaginal discharge or abnormal uterine bleeding, especially in the age group of 50-59 years, should be investigated to exclude malignancy. Public health education should be intensified to encourage early health seeking behavior in order to diagnose cervical malignancy at an early age especially when they have clinical symptoms of blood-stained vaginal discharge or abnormal uterine bleeding.