Miracle-dz/UniFAR-FTUs huggingface dataset:
PENGARUH KINERJA KEUANGAN DAN KINERJA LINGKUNGAN TERHADAP NILAI PERUSAHAAN PERTAMBANGAN DI ISSI PERIODE 2013-2017

This study analyzed the influence of Islamic Social Reporting (ISR), Return on Asset, and Current Ratio on the value of the companies which were registered in ISSI in 2013-2017. This research used panel data regression analysis to combine time series data and cross section data. The results of the research with estimation model of Random Effect showed that ISR, ROA and CR partially had significant effects on the value of the company. ISR, ROA and CR silmutanously affect on the value of the mining companies registered in ISSI 2013-2017.Keywords: Islamic Social Reporting, Return on Asset, Current Ratio, and Firm Value
Mixed elastohydrodynamic lubrication and fatigue calculation for rough surface contacts using a synthesised running-in model

This thesis presents a method to investigate the contact and deformation of rough surfaces such as those found on the teeth of gears. As-manufactured rough surfaces undergo a process known as “running-in”, in which the geometry of the surface is changed by interaction with the counterface when they are first loaded together. The process of surface roughness modification in machine elements when loads are applied was studied. This is a plastic deformation that modifies the roughness asperities to form the surface finish that characterises the components during their useful life. Protection of heavily loaded machine element surfaces is provided by mixed elastohydrodynamic lubrication (EHL) which depends critically on the component surface roughness. A procedure was developed to synthesise the running-in process based on real as- manufactured profiles. Surface roughness profiles obtained from transverse ground test disks were used to simulate asperity modification during running-in under load. This simulation is based on a detailed analysis of the way in which the surface roughness asperity tips change shape during running-in. Information on these changes was extracted by measuring surface roughness profiles before and after running-in and quantifying the statistical changes seen in the asperity tip radii of curvature. The surfaces were run against each other in mixed EHL analyses and the radius of curvature of asperity peaks subjected to extreme loading was increased in a controlled fashion to synthesise plastic deformation. The process was developed by comparison with the corresponding run-in profiles and with observed changes in asperity peak radii of curvature. Simulations were conducted for a range of different surface roughness pairs with various operating conditions. The synthesised and measured run-in surfaces were compared in various ways. Their geometry was examined in terms of form and asperity peak radii of curvature. Rolling / sliding EHL contact analyses were performed and their behaviour in terms of peak asperity pressure and direct asperity contact was assessed. The transient mixed EHL analysis results were used to apply surface loading to the rough profiles to obtain stress histories, which were the basis of the fatigue modelling then carried out. Finally, experimental work was implemented to detect the micropits developing on the rough iv surfaces using surface measurements taken during endurance tests, and a good agreement was found when compared with numerical fatigue model.
THE IMPACT OF WHATSAPP GROUP ON UNDERGRADUATE STUDENTS‟ WRITING IN THE INDONESIAN TERTIARY CONTEXT

The popularity of WhatsApp Group in the academic major has raised the interest of researchers and practitioners in exploring its potential benefit in teaching EFL aspects. This present paper attempts to investigate whether the use of WhatsApp Group as a learning media might enhance undergraduate students‘ writing ability. It also explores the problems affecting the use of WhatsApp Group in writing class.There were fifty-eight undergraduate students who participated in this study. They enrolled in the writing course and were in the third semester in the academic years of 2018/2019.The subjects were randomly assigned into two groups, experimental group and control group. The research data were collected using pretest-posttest design and interview. The results of t-test scoresindicated that WhatsApp Group significantly outperformed the students‘ writing performance. Furthermore, there were technical, education, and instruction problems dealing with the use of WhatsApp Group to improve the students‘ readiness to participate in writing activities. Thus, WhatsApp Group is considered as a potential alternative of an instructional media for educational purposes to bring beneficial to students‘ knowledge of language and to help the students to work independently andcooperate with the others. Keywords: educational purposes, students‘ wrtiting, WhatsApp Group
Glycosylation and dimerization of the human δ-opioid receptor polymorphic variants

Cellular signaling by G protein-coupled receptors (GPCRs) governs a wide array of physiological functions throughout the body. The human δ-opioid receptor (hδOR) is a GPCR that modulates the sensation of pain and mood and has great potential for the treatment of pain and a variety of neurological disorders. A common single-nucleotide polymorphism (SNP) in the extracellular Nterminal tail of hδOR changes Phe to Cys at position 27. Using various biochemical and cell biological methods, the study demonstrates that several events during receptor biosynthesis and cell surface delivery are affected by the SNP. These events participate in the multifaceted regulation of the receptor and modulate receptor behavior at the cell surface. Two distinct pathways were shown to scrutinize the quality of the synthesized hδOR in the endoplasmic reticulum (ER) and target some for degradation in N-glycan-dependent and -independent ways. The hδORCys27 that matures inefficiently required N-glycan-mediated interactions with the lectin-chaperone calnexin to be expressed in a fully functional form at the cell surface, whereas the N-glycan-independent pathway was sufficient for hδORPhe27. For both variants, the N-glycan-independent quality control, which is likely to operate as a back-up pathway, led to a more rapid export from the ER and receptors at the cell surface that were less stable. Receptor dimerization emerged as an important regulatory step for receptor cell surface delivery. In co-transfected cells, interactions between the newly-synthesized variants led to the retention and subsequent ER-associated degradation of hδORPhe27. This dominant-negative attenuation of hδORPhe27 cell surface expression by hδORCys27 may have unpredictable consequences for opioid signaling in heterozygous individuals. Finally, the study shows that N-acetylgalactosamine (GalNAc)-type O-glycosylation catalyzed in the Golgi modulates hδOR expression at the cell surface by enhancing receptor stability and inhibiting constitutive downregulation. The modification of Ser residues in the receptor Nterminus by GalNAc-transferase 2 was affected by the SNP, which presents another distinction in the cellular processing of the two variants. The findings highlight the importance of the biosynthetic pathway in the regulation of GPCR behavior and pave way for strategies for treatments targeting GPCRs at this level.
Terrestrial and satellite radar interferometry applications for ground deformation investigations in urban subsidence detection, landslide velocity monitoring, and novel failure discovery

iii LIST OF FIGURES . vii LIST OF TABLES . x ACKNOWLEDGEMENTS . xi CHAPTER 1 GENERAL INTRODUCTION . 1 1.1 Interferometric Radar Remote Sensing . 1 1.2 Radar Remote Sensing in Deformation Measurements . 2 1.3 Thesis Organization . 3 CHAPTER 2 HIGH RESOLUTION DISPLACEMENT MONITORING OF A SLOW VELOCITY LANDSLIDE USING GROUND BASED RADAR INTERFEROMETRY . 5 2.4 Abstract . 5 2.5 Introduction . 6 2.6 Background: Landslide monitoring radar interferometry from terrestrial platforms . 9 2.7 Existing displacement monitoring challenges . 10 2.8 Methods: Line of sight measurements and radar displacement measurement . 14 2.9 Methods: Radar system configuration . 14 2.10 Methods: Imagery processing and interferogram generation . 16 2.11 Methods: Phase unwrapping and displacement inversion . 16 2.12 Methods: Phase unwrapping and displacement inversion . 17
Understanding visual behaviour within the urban environment to optimise lighting

A review of the literature suggests that current guidelines for road lighting lack a clear empirical basis. Where there is evidence, this tends to be based on motorists or pedestrians: there is little, if any, consideration given to the needs of cyclists. This thesis presents an investigation of lighting for cycling after dark within an urban environment. Three empirical investigations were conducted. A field survey was conducted to investigate the influence of the ambient light level on the tendency to cycle. Mobile eye-tracking was used to investigate the gaze behaviour of cyclists in natural settings, using two parallel measurements to reveal the critical of these fixations: performance on an audio dual-task and skin conductance response (SCR), and by that improved the ecological validity of previous similar research. A laboratory experiment was conducted to investigate obstacle detection under variations in the type, location, and level of lighting. The field study revealed that cycling increases when the ambient light level is higher. This suggests that road lighting might be a tool to encourage more cycling. The eye-tracking study suggested that observing the path ahead is a critical task, reflecting a tendency to search for possible obstacles on the road. Post hoc analysis of the eye-tracking data also suggested an influence of ambient light level on gaze towards aesthetic elements (architectural features) of the environment with such elements are suggested by the literature to be associated with positive cycling experience: this suggests that appropriate road lighting motivates the choice to cycle. The detection experiment revealed two significant effects: first; that road lighting and bicycle lighting may conflict. In other words, using bicycle lighting on a lit road may impair detection performance, not improve it. Second; that detection is improved when the front bicycle lamp is located on the wheel hub rather than the handlebar.
The diversity of coronaviruses in Southern African bat populations

ENGLISH ABSTRACT: Coronaviruses are RNA viruses encompassing four genera. The alpha- and betacoronaviruses have commonly been associated with mild disease in humans. However, outbreaks of severe respiratory disease in 2002 and 2012 led to the identification of novel highly pathogenic human coronaviruses, SARS- and MERS-CoV, respectively. Bats, order Chiroptera, are believed to be the reservoir host from which all mammalian coronaviruses have emerged. To date, few studies have been published on coronaviruses in South African bats. With little known about the diversity and prevalence of bat coronaviruses in this region; this study aimed to describe the existing coronavirus diversity within South African bat populations as well as factors that might influence bat-coronavirus ecology. It detected nine different coronavirus species, eight alphacoronaviruses and one betacoronavirus, from ten different bat species. The study not only demonstrated that diverse coronaviruses can be found in different bat species of Southern Africa but lends additional support to an ongoing circulation of MERS-related betacoronaviruses in South African bats, with divergent variants detected in two different vespertilionid bat species. A species-specific surveillance of Neoromicia capensis (Cape serotine) bats detected three different bat coronavirus species and revealed genetic diversity across different geographic regions. Several instances of coinfection with two different coronaviruses were detected, demonstrating the potential for recombination that could lead to the emergence of a new coronavirus that might have zoonotic potential. This study demonstrated that both host and environmental factors may influence CoV ecology. Female Neoromicia capensis bats trapped at low altitude sites within the Forest biome had the highest likelihood of being coronavirus positive. Discrepancies between detection rates obtained with different screening assays led to the adoption of an improved approach and recommendations for future bat coronavirus surveillance studies were made. %%%%AFRIKAANSE OPSOMMING: Koronavirusse is RNA virusse wat vier genera insluit. Die alfa- en betakoronavirusse word algemeen geassosieer met minder ernstige siektes by mense. Uitbrakings van ernstige respiratoriese siektes in 2002 en 2012 het egter gelei tot die identifisering van nuwe hoogs patogeniese menslike koronavirusse, SARS- en MERS-koronavirus, onderskeidelik. Vlermuise, orde Chiroptera, word beskou as die reservoir gasheer, wat tot die oorsprong van alle soogdierkoronavirusse gelei het. Tot dusver is min studies oor koronavirusse in Suid-Afrikaanse vlermuise gepubliseer. Met min kennis van die diversiteit en voorkoms van vlermuiskoronavirusse in hierdie streek; het hierdie studie ten doel om die bestaande koronavirusdiversiteit binne Suid-Afrikaanse vlermuispopulasies asook faktore wat vlermuis-koronavirus-ekologie kan beinvloed, te ondersoek en beskryf. Nege verskillende koronavirus spesies, agt alfakoronavirusse en een betacoronavirus, is in…
Fate of Dysfunctional Bladder after Pediatric Renal Transplantation

Introduction: Graft function on long term into patients with LUTD is still a myth, So, we aimed know the natural history of LUTD and graft function into patient with abnormal lower urinary tract. Patient and methods: The study was conducted by retrospective review of 129 files of pediatric live renal transplant patients; Patients in either group had clinical evaluation of lower urinary tract function and assessment of graft functions at least one year after RT. Results: On evaluation the magnitude of change of cystometric variables we found 57% improvement of incidence of urodynamic detrusor overactivity and 48% improvement in patient categorized as poor/decreased compliance. There was 90% increase in the number of patients with adequate capacity. Patients showed 55.5% decrease in the number of patient with high PVR. Conclusion: Live donor renal transplant into pediatric patients with LUTD due to organic or neurogenic lower urinary tract pathology showed high serum creatinine on long term follow up.
A Discussion on the measurement and interpretation of changes of strain in the Earth - Earth tides and their place in geophysics (summary)

The experimental study of tidal phenomena in the solid Earth has been pursued for a century and, in particular, the last 15 years since the I.G. Y. has seen a spectacular growth in activity. The geophysical significance of the work has remained limited however, and it is necessary to study possible reasons for these shortcomings. Work in the U.K. on tilt and gravity variations has helped to identify some of the relevant problems associated with the philosophy of instrumentation and its deployment, calibration, experimental repeatability, and analytical procedures. Here the importance of the oceanic influence is clear, whereas elsewhere it has not always been accorded sufficient attention. The future of the discipline may lie in a decline in interest in body effects and a greater concentration upon the mantle, the crust and their inhomogeneities in which experimental and theoretical studies proceed in parallel.
Genetic Diversity in Banana and Plantains Cultivars from Eastern DRC and Tanzania Using SSR and Morphological Markers, Their Phylogenetic Classification and Principal Components Analyses

Bananas and plantains are edible and vegetatively propagated parthenocarpic species of the genus Musa. They are used as staple food, dessert and cash crop by more than hundred millions of people throughout the world. However, the crop is threatened by several pests and diseases in central and eastern Africa. One way of partly solving this problem is to have diploids which have desirable traits currently lacking in the AAA- Lujugira-Mutika subgroup. The study assessed through 21 microsatellite markers pairs the cladistic closeness of the diploid AA-Mshale accessions with AAA-Lujugira-Mutika with the purpose of inclusion in breeding programmes. Results showed that the eight studied accessions of AA-Mshale were different from each other. AA-Mshale malembo was fairly well established to be among the ancestor of Lujugira-Mutika, suggesting the determinism of its pollen viability and the level of resistance to pests for including in breeding programmes. The use of two pairs of microsatellites per chromosomes linkage group established the existence of alleles ’ deletion, recombination or non-annealing. The closeness among AA-Mshale and AAA-subgroups (Ibota, Gros Michel and Green Red) so far established through other techniques was confirmed. The results recommend the use of microsatellite markers, covering 11 linkage groups for cultivar identification and diver- sity study.
UK Specialists’ and GDPs’ Use of Systemic and Local Antimicrobial Administration in Periodontal Therapy: A Questionnaire Study

Aim: The aim of the present study was to evaluate the use of antimicrobials, the prescription patterns and the reason(s) for prescribing antimicrobials when treating periodontal disease in selected UK General Dental Practitioner (GDP) and Periodontal Specialists. Materials & Methods: The questionnaire consisted of 21 questions and was sent to 488 Periodontal Specialists and 488 GDPs. Data management and analysis was performed using Microsoft Excel, SPSS® version 22.0 software and frequency distributions, cross tabulation tables and graphs were constructed from the data. Any association between variables was tested at the 5 % level of significance (P≤ 0.05). Results: The questionnaires were completed by the Specialists (38.72%) (n=189) and 23.36% (n=114) of the GDPs. The results indicated that the use of systemic and local antimicrobials followed the current guidelines. Specialists prescribed more systemic antimicrobials than the GDPs, although Specialists limited the use of local antimicrobials. The GDPs reported that decision making was difficult when to use local antimicrobials although recognised that using local antimicrobials were more effective than root surface debridement alone. Other reasons for using antimicrobials were based either on the patient request or patient satisfaction with the treatment. Lower frequency of antimicrobial use was reported in regeneration and implant procedures by both Specialists and GDPs although the Specialists were more inclined to use antibiotics/antimicrobials in these procedures. Conclusions: The results of the study suggested that there was a need for dentists to follow current guidelines when prescribing antibiotics/antimicrobials in order to avoid unnecessary prescriptions, antibiotic resistance and adverse drug reactions.
A study of Candida albicans and non-albicans Candida species isolated from various clinical samples and their antifungal susceptibility pattern

Background : Candida species are the most common cause of fungal infections worldwide. Candida albicans has been the most common causative agent until recent past but frequency of nonalbicans Candida (NAC) species is on the rise. This changing epidemiology and increase in resistance to antifungal agents makes it important to identify Candida up to the species level and know its antifungal susceptibility pattern. aim : To provide data on Candida species prevalence and to highlight the need of speciation of Candida and its antifungal susceptibility testing. Material and methods : For blood cultures, BacT/ALERT blood culture automated system (BioMérieux) was used. Candida was identified initially by direct microscopic examination of samples received and culture was done on SDA with antibiotic. Differentiation of Candida albicans and NAC species was done by germ tube test and final identification and antifungal susceptibility testing were done using Vitek 2 compact. result - Candida Other NAC spp. to reduced susceptibility to amphotericin conclusion: There is a significant epidemiological shift in candidiasis cases due to NAC species. Based on the present results and trends, it becomes essential to routinely identify Candida isolates up to species level, and detect evolving resistant strains by antifungal susceptibility testing wherever feasible.
Expressão das proteínas PLUNC/BPIF e produtos da fusão MECT1-MAML2 em células de carcinoma mucoepidermoide salivar : Expression of protein PLUNC/BPIF and fusion MECT1-MAML2 products in salivary mucoepidermoid carcinoma cells

Mucoepidermoid carcinoma is the second most common salivary gland tumour and the most frequent malignant salivary gland tumour. About one-third to half of all mucoepidermoid carcinomas demonstrate a specific translocation t(11;19)(q21;p13), known as MECT1-MAML2 fusion oncogene, which is associated with varied mechanisms involving cell differentiation and proliferation. Previous studies have shown that the presence of the translocation can result in a better prognosis, as well as the presence o proteins of PLUNC/BPIF family as important biomarkers of MEC. The aim of this study is to investigate the presence of products of the fusion gene MECT1-MAML2 and protein BPIFA2 in MEC. 40 cases of MEC were evaluated using immunohistochemistry for BPIFA2, MECT1, MAML2 and MECT1-MAML2. Both MECT1 and the fusion protein showed being significantly correlated with BPIFA2. The MAML2 antibody was not correlated with the other antibodies and it might not be recommended to be used as a biomarker in MEC. Fluorescent in situ hybridization was performed in 21 cases and showed significant correlation with fusion gene positivity and low grade tumour (p<0.05). Our findings suggest that biomarkers MECT1, MECT1-MAML2 and BPIFA2 provide useful information for MEC diagnosis, as well as play an important role as a key to optimizing diagnosis and potential targeted therapies.
First record of Foulassi Screeching Frog, Arthroleptis adelphus (Perret, 1966) (Anura, Arthroleptidae, Arthroleptinae), from Nigeria, with notes on its phylogenetic position

We report the first known occurrence of the Foulassi Screeching Frog, Arthroleptis adelphus (Perret, 1966), from Nigeria. A specimen of A. adelphus was collected during herpetological survey work conducted in Cross River National Park, south-eastern Nigeria. Morphometrics and mitochondrial 16S rRNA gene confirm identity of the specimen. Matrilineal genealogy reveals a sister relationship of A. adelphus from Nigeria with individuals from south-western Cameroon. Genetic analysis further shows geographic structuring and divergence among populations of A. adelphus from the Guineo–Congolian forest region. We offer updates to the IUCN geographic range of A. adelphus.