Miracle-dz/UniFAR-FTUs huggingface dataset:
A Self-Healing Gel with an Organic–Inorganic Network Structure for Mitigating Circulation Loss

Lost circulation control remains a challenge in drilling operations. Self-healing gels, capable of self-healing in fractures and forming entire gel block, exhibit excellent resilience and erosion resistance, thus finding extensive studies in lost circulation control. In this study, layered double hydroxide, Acrylic acid, 2-Acrylamido-2-methylpropane sulfonic acid, and CaCl2 were employed to synthesize organic-inorganic nanocomposite gel with self-healing properties. The chemical properties of nanocomposite gels were characterized using X-ray diffraction, Fourier transform infrared spectroscopy, scanning electron microscope, X-ray photoelectron spectroscopy and thermogravimetric analysis. layered double hydroxide could be dispersed and exfoliated in the mixed solution of Acrylic acid and 2-Acrylamido-2-methylpropane sulfonic acid, and the swelling behavior, self-healing time, rheological properties, and mechanical performance of the nanocomposite gels were influenced by the addition of layered double hydroxide and Ca2+. Optimized nanocomposite gel AC6L3, at 90 °C, exhibits only a self-healing time of 3.5 h in bentonite mud, with a storage modulus of 4176 Pa, tensile strength of 6.02 kPa, and adhesive strength of 1.94 kPa. In comparison to conventional gel, the nanocomposite gel with self-healing capabilities demonstrated superior pressure-bearing capacity. Based on these characteristics, the nanocomposite gel proposed in this work hold promise as a candidate lost circulation material.
Effect of the nitrification inhibitor (DMPP) on soil nitrous oxide emissions and yield in a lettuce crop in Queensland, Australia

The use of nitrification inhibitors, in combination with ammonium based fertilisers, has been promoted recently as an effective method to reduce nitrous oxide (N2O) emissions from fertilised agricultural fields, whilst increasing yield and nitrogen use efficiency. However, to date no data is available on the use of nitrification inhibitors in sub-tropical vegetable systems. A field experiment investigated the effect of the nitrification inhibitor 3,4-dimethylpyrazole phosphate (DMPP) on N2O emissions and yield from lettuce production in sub-tropical Australia. Soil N2O fluxes were monitored continuously over 120 days with a fully automated system. Measurements were taken from three subplots for each treatment within a randomized complete blocks design. Cumulative N2O emissions over the 120 day observation period amounted to 191, 93 and 46 g-N ha-1 in the conventional fertiliser (CONV), the DMPP treatment and the zero fertiliser (0N) respectively. Consequently, the use of DMPP decreased seasonal N2O emissions by more than 50%, but had no significant impact on lettuce yield. The temporal variation of N2O fluxes showed only low emissions over the lettuce cropping period in all treatments, but significantly elevated emissions were observed in the CONV fertilized and DMPP treatment postharvest, following lettuce residues being incorporated into the soil. This study highlights that DMPP can substantially reduce N2O emissions from vegetable cropping systems. It also emphasizes that N input from vegetable crop residues incorporated into the soil after harvest can lead to substantially elevated N2O emission. Hence, in such systems post-harvest emissions need to be in the centre of attention for developing N2O mitigation strategies.
Novel Flowchart Guiding the Non-Surgical and Surgical Management of Peri-Implant Complications: A Narrative Review

Peri-implant diseases, such as peri-implant mucositis and peri-implantitis, are induced by dysbiotic microbiota resulting in the inflammatory destruction of peri-implant tissue. Nonetheless, there has yet to be an established protocol for the treatment of these diseases in a predictable manner, although many clinicians and researchers have proposed various treatment modalities for their management. With the increase in the number of reports evaluating the efficacy of various treatment modalities and new materials, the use of multiple decontamination methods to clean infected implant surfaces is recommended; moreover, the use of hard tissue laser and/or air abrasion techniques may prove advantageous in the future. Limited evidence supports additional effects on clinical improvement in antimicrobial administration for treating peri-implantitis. Implantoplasty may be justified for decontaminating the implant surfaces in the supracrestal area. Surgical treatment is employed for advanced peri-implantitis, and appropriate surgical methods, such as resection therapy or combination therapy, should be selected based on bone defect configuration. This review presents recent clinical advances in debridement methods for contaminated implant surfaces and regenerative materials for treating peri-implant bone defects. It also proposes a new flowchart to guide the treatment decisions for peri-implant disease.
Geomagnetic and Cosmic Ray Activity Effect on Heart Rate during the Solar Cycle 24

The number of investigations relevant to the study of geomagnetic activity, solar events, and cosmic rays, i.e., space weather phenomena, and their impact on human health has increased dramatically over the past few years. Numerous studies examine the reaction of the cardiovascular, nervous, and other functional systems to variations observed in geospace. These studies examine the behavior of human physiological parameters not only during different levels of activity of the Sun and in the interplanetary space (from no activity to remarkably intense activity) but also through geomagnetic activity storms and Forbush decreases. Here, individuals from the Hippocratio General Hospital in Athens, the cardiology clinics of Nikaia General Hospital in Piraeus, and the Heraklion University Hospital in Crete, Greece, were assessed during the time period from 2011 until 2018. The heart rate of the individuals was recorded every hour via the Holter electrocardiogram method. Data were analyzed using the analysis of variance (ANOVA) and the method of superimposed epochs. The investigation covers not only the ascending but also the descending phase of the solar cycle 24 (lasting until 2019 and with its maximum in the year 2014).
Healthcare Quality from the Perspective of Patients in Gulf Cooperation Council Countries: A Systematic Literature Review

With the increased focus on patient-centered care, consensus on healthcare outcomes of importance to patients becomes crucial. Based on a systematic review of the literature, this study confirms the perspectives of patients on healthcare quality in GCC countries. Online databases were searched for relevant peer-reviewed articles published from 2012 to 2023. Twenty-two articles retrieved from the search were qualitatively analyzed based on the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) guidelines. Most articles (90%) reported studies conducted in Saudi Arabia. Patients in GCC countries face common problems in the care delivery process, which contribute to negative perceptions of quality. These problems include diagnostic and medication errors, provider–patient communication problems, missed appointments with physicians, problems in emergency care access due to geographical distance and transportation barriers, long waiting times, and physical environments. Notably, healthcare quality is perceived to be an outcome of multiple factors dependent on the location and category of healthcare service providers; for instance, disparities in perceptions of quality were observed between patients attending Primary Health Care (PHC) centers in rural and urban areas. Issues such as lack of equitable healthcare delivery and deficiencies in Emergency Medical Services (EMS) effectiveness were disparately recognized as quality concerns by different patient populations. The findings provide insights into healthcare quality and area of weakness needing strategies and policies to ensure patient-centered, safe, equitable, timely, and effective healthcare. Healthcare providers and policymakers in GCC countries can use the results to plan, assess, and improve care delivery. Trial registration: PROSPERO ID: CRD42022326842.
Effect of exercise and pharmacotherapy on non-alcoholic fatty liver disease

Objectives: Nonalcoholic fatty liver disease is one of the emerging liver diseases affecting 20%–30% of the population creating a burden on public health worldwide and has been associated with the causation of multiple diseases. Besides exercise, several drugs are being used in patients based on clinical evidence especially vitamin E, a potent antioxidant to reduce the oxidative stress responsible for the development and progression of nonalcoholic fatty liver disease. This study aims at evaluating the effect of exercise and pharmacotherapy on nonalcoholic fatty liver disease. Design: A prospective follow-up study with purposive sampling was done at a liver clinic for 3 months. Baseline characteristics such as anthropometric measurements and biochemical parameters were recorded and compared after 3 months to determine the effect of therapy. Descriptive analysis using a parametric test was used to assess the change in biochemical parameters and a non-parametric test was applied to find out the association between non-pharmacological and pharmacological approaches. Results: Out of 177 patients, 67.2 % were male and 32.8% were female with the mean age ±SD of 46.8 ± 12.06 years. Mean ± SD weight and body mass index of the patients were changed from 74.88 ± 11.61 kg to 72.37 ± 11.61 kg and from 28.41 ± 4.02 kg/m2 to 27.31 ± 4.58 kg/m2 respectively which was found to be statistically significant. There was a significant change in all the biochemical parameters with the p-value < 0.05 through both non-pharmacological and pharmacological approaches. Conclusion: Nonalcoholic fatty liver disease management through exercise and pharmacotherapy shows significant improvement in biochemical parameters indicating that alone or in combination with both approaches play an effective role in treating nonalcoholic fatty liver disease.
Interrogative Suggestibility and Ability to Give Resistant Responses in Children with Mild Intellectual Disabilities and Borderline Intellectual Functioning

Children with intellectual disabilities can be victims of crimes but are generally deemed less reliable in the forensic context than children without disabilities. Their deficits may cause inaccurate recall, greater memory errors, and greater suggestive vulnerability. The aim of the present study is to verify the effects of intellectual abilities on recall tasks, levels of suggestibility, vulnerability to negative social pressure, and Resistant Behavioural Responses (RBR). The study involved 120 children aged 7–16 years who were administered the GSS2 (1997) and Raven Matrices. Forty children had a diagnosis of mild intellectual disability (MID), 40 had borderline intellectual functioning (BIF), and 40 were typically developing peers. Children with MID and BIF showed more errors in distortions, inventions, and confabulations at the recall task and higher levels of suggestibility.Low IQs reduced the ability of source monitoring and led to less resistant responses to misleading questions. IQ affected resistant responses both at the first and second suggestive interview, reducing both source monitoring capabilities and the ability to manage social pressure. Age may impact the ability to provide resistant responses but only in the first suggestive interview (Yield 1), which depends more on the maturity of cognitive processes involved in interrogative suggestibility.
Assessment of Burnout Among Emergency Medicine Residents in Saudi Arabia: A Cross-Sectional Survey

Background: Burnout syndrome is a frequent challenge faced in the emergency department. There exists a dearth of clinical evidence regarding the risk and occurrence of burnout, among emergency residents in Saudi Arabia. Therefore, this study was conducted to assess the parameters of burnout in this cohort. Methods: This prospective, cross-sectional study was conducted via an online survey using Maslach Burnout Inventory for Healthcare Professionals (MBI-HSS) questionnaire. All emergency medicine residents registered under the country's residency program were invited to participate. The relative importance index (RII) analysis was used to describe the frequency of the MBI-HSS indicators. The t-test of independent groups and the one-way analysis of variance were used to assess the impact of demographic and professional factors. Results: A total of 73 residents completed the questionnaire. Low PA was reported by 53.4% while medium to high DP and EE were reported by 84.9% and 67.1% residents respectively. Female residents had significantly higher EE versus males. Age, marital status and number of children had no correlation with burnout. Emergency residents serving at hospitals of the Ministry of Health reported significantly higher levels of burnout, versus other institutions. The final year of the residency program showed significantly lower levels of burnout than the earlier years. Conclusion: This is the first study from Saudi Arabia, assessing the parameters of burnout, specifically among emergency medicine residents. The study has shown alarmingly high levels of DP, EE and low PA and warrants urgent remedial measures to curb burnout among emergency residents.
IMPACT OF DILUTION ON BIOMETHANATION OF FRESH WATER HYACINTH

Water hyacinth (Eichhornia crassipes) is a noxious weed that has attracted worldwide attention due to its fast spread and congested growth, which lead to serious problems in navigation, irrigation, and power generation. The concept of using aquatic plants for conversion to energy is gaining attention in tropical and sub tropical regions of the world where warm climate is conducive to the plant growth through the year. Anaerobic digestion of animal, agricultural and industrial wastes has been widely studied. However, very little work has been done using aquatic plants particularly water hyacinth. The literature review indicated that water hyacinths can be rich in nitrogen, up to 3.2% of DM and have a C/N ratio around 15. The water hyacinth can be used as a substrate for biogas production. The sludge from the biogas process contains almost all of the nutrients of the substrate and can be used as a fertilizer. In the present work biomethanation of fresh water hyacinth with different amount of water was carried out in mesophilic temperature range of 30°C to 37°C for a period 60 days. Fermentation slurry of water hyacinth to water in the ratio 1:4 (FWH-1:4) produced maximum biogas yield of 0.245 l/gVS, followed by FWH-1:5 and FWH-1:3.
Bioaccumulative contaminants in marine mammals: uptake and effects

Supervisory Committee Dr Peter S. Ross (School of Earth and Ocean Science s; Fisheries and Oceans Canada) Co-Supervisor Dr Michael J. Whiticar (School of Earth and Ocean S ciences) Co-Supervisor Dr Robie W. Macdonald (School of Earth and Ocean Sc iences) Departmental Member Dr Caren Helbing (Department of Biochemistry and Mi crobiology) Outside Member This thesis provides insights into the transport an d f te of contaminants of concern (polychlorinated biphenyls (PCBs), polybrominated d iphenyl ethers (PBDEs) and mercury (Hg)), as well as results on the impacts of these compounds on marine mammal
Nicotinamide Phosphoribosyltransferase Positive Allosteric Modulators Attenuate Neuronal Oxidative Stress

Evidence supports boosting nicotinamide adenine dinucleotide (NAD+) to counteract oxidative stress in aging and neurodegenerative disease. One approach is to enhance the activity of nicotinamide phosphoribosyltransferase (NAMPT). Novel NAMPT positive allosteric modulators (N-PAMs) were identified. A cocrystal structure confirmed N-PAM binding to the NAMPT rear channel. Early hit-to-lead efforts led to a 1.88-fold maximum increase in the level of NAD+ in human THP-1 cells. Select N-PAMs were assessed for mitigation of reactive oxygen species (ROS) in HT-22 neuronal cells subject to inflammatory stress using tumor necrosis factor alpha (TNFα). N-PAMs that increased NAD+ more effectively in THP-1 cells attenuated TNFα-induced ROS more effectively in HT-22 cells. The most efficacious N-PAM completely attenuated ROS elevation in glutamate-stressed HT-22 cells, a model of neuronal excitotoxicity. This work demonstrates for the first time that N-PAMs are capable of mitigating elevated ROS in neurons stressed with TNFα and glutamate and provides support for further N-PAM optimization for treatment of neurodegenerative diseases.
Journal of Brewing and Distilling

A limited number of samples of gin and related alcoholic beverages have been analysed using high-resolution 1 H NMR Spectroscopy to investigate the effectiveness of the technique as a means of gaining insight into their chemical composition. Various types of gin were investigated, including London Dry, Compound, Old Tom, and fruit gins. The study utilized some advanced NMR experiments, including multiple solvent suppression and total correlation spectroscopy, allowing for the identification and partial quantification of constituents, including terpenes, carbohydrates, organic acids, and phenolic compounds. Overall, based on the evidence of this focused study, NMR shows great promise for the chemical analysis of gins.
Exploring the role of goal-dependent processes in action slips under time pressure.

People sometimes emit frequently practiced responses that were previously effective in achieving desired outcomes but are no longer appropriate in the current context. While dual-process theories attribute these action slips to goal-independent, associative processes, we propose that errors in the expectancies about action outcomes contribute to their occurrence. To investigate this, we first replicated an influential study by Hardwick et al. (2019), demonstrating the occurrence of action slips following extensive stimulus-response training when individuals are required to respond rapidly. Building on this foundation, we conducted two additional experiments using a similar procedure, incorporating a measure of outcome expectancies under time pressure. Our findings provide compelling evidence for errors not just in selected responses but also in expected outcomes of these responses, particularly in early time intervals. These results highlight the possible role of goal-directed processes in action slips under time pressure, advancing our understanding of the cognitive mechanisms underlying suboptimal behavior.
The Relationship between Online Learning, Associated Factors and Emotional/Behavioral Problems in Primary School 1st Grade Students

Aim: The use of online learning, which has spread rapidly worldwide in recent years, has increased considerably with the COVID-19 pandemic. The study aimed to evaluate the online learning experience of children attending primary school 1st grade and the relationship between online learning, related factors, and Emotional/Behavioral problems. Materials and Methods: This study was carried out with 378 mothers who have a child attending primary school 1st grade. Demographic data were assessed with the Sociodemographic Data Form, which included information about the online learning process and school, and the parent-rated Strengths and Difficulties Questionnaire (SDQ) to assess emotional/behavioral problems. Results: 50.5% of the mothers reported that their children experienced emotional/behavioral problems, while 45.3% reported that online learning exacerbated their children's emotional/behavioral problems. SDQ Emotional problems score was significantly higher in girls, while SDQ Conduct problems and Hyperactivity/inattention subscores, and SDQ total scores were significantly higher in boys. The SDQ peer problems subscore and SDQ total scores of illiterates were significantly higher than those of literates. There was a significant negative correlation between the extracurricular screen time and all SDQ scores except the prosocial behavior subscore. The SDQ conduct problems and peer problems subscores and SDQ total scores of children with regular activities/hobbies were significantly lower than the others, while the SDQ prosocial behavior score was significantly higher. Conclusion: Our study findings showed that online learning negatively affected almost half of the children in terms of emotional/behavioral problems for different reasons, gender can lead to differences in emotional/behavioral problems in early childhood, illiterate children and children with increased extracurricular screen time may be more at risk in terms of emotional/behavioral problems and regular activities/hobbies may contribute positively to the process.
ON COLOURING ORIENTED

We prove that for every oriented graph D and every choice of positive integers k and ℓ , there exists an oriented graph D ∗ along with a surjective homomorphism ψ : V ( D ∗ ) → V ( D ) such that: (i) girth( D ∗ ) ≥ ℓ ; (ii) for every oriented graph C with at most k vertices, there exists a homomorphism from D ∗ to C if and only if there exists a homomorphism from D to C ; and (iii) for every D -pointed oriented graph C with at most k vertices and for every homomorphism φ : V ( D ∗ ) → V ( C ) there exists a unique homomorphism f : V ( D ) → V ( C ) such that φ = f ◦ ψ . Determining the oriented chromatic number of an oriented graph D is equivalent to finding the smallest integer k such that D admits a homomorphism to an order-k tournament, so our main theorem yields results on the girth and oriented chromatic number of oriented graphs. While our main proof is probabilistic (hence non-constructive), for any given ℓ ≥ 3 and k ≥ 5, we include a construction of an oriented graph with girth ℓ and oriented chromatic number k .
Echocardiographic Findings of Children with Down Syndrome

Objective: Down syndrome is the most common well-known chromosomal disorder. The incidence of congenital heart disease (CHD) in these patients is high and it is the most important cause of mortality. In this study, we reviewed the comorbid CHDs and their characteristics in patients with the diagnosis of Down syndrome. We compared our results with the results of studies conducted in different regions of our country in different years. Materials and Methods: Between January 2020 and December 2022, data from a total of 385 patients (175 females, 210 males) with Down syndrome were evaluated. The age of the mothers at the time of delivery and the availability of prenatal diagnosis information in accessible patients were determined. Results: Of 385 patients with Down syndrome, 38.2% (n=147) had CHD. Among patients with CHD, 57 patients had atrioventricular septal defect (AVSD) (38.7%), 35 patients had perimembranous ventricular septal defect (23.8%), 24 patients had secundum atrial septal defect (16.3%), 8 patients had patent ductus arteriosus (5.4%), and 10 patients without AVSD had CHD with multiple left-to-right shunts (6.8%). The most common cyanotic CHD was tetralogy of Fallot (n=7, 4.7%). Complete AVSD was present in 63.1% of AVSD patients. CHD was present in 36.2% of boys and 40.6% of girls. Among all female patients, 17.1% had AVSD, while this rate was 12.8% among all male patients (p<0.05). The mean maternal age at delivery was 32.59±6.9 (17-48) years. It was found that children with Down syndrome whose mothers had a maternal age of 33.5 years and above had a lower rate of CHD. Of the 170 mothers for whom prenatal diagnosis information was available, 58.2% (n=99) had a prenatal diagnosis. Conclusion: Prenatal diagnosis opportunities have increased and become widespread over the years. However, no significant change was observed in the rates of CHD, which is most frequently responsible for mortality in children with Down syndrome. It is appropriate for every expectant mother with a prenatal diagnosis to be referred for fetal echocardiography or postnatal transthoracic echocardiography.