Miracle-dz/UniFAR-FTUs huggingface dataset:
Impact of Oral Administration of Lactiplantibacillus plantarum Strain CNCM I−4459 on Obesity Induced by High-Fat Diet in Mice

Recent evidence suggests that some lactobacilli strains, particularly Lactiplantibacillus plantarum, have a beneficial effect on obesity-associated syndromes. Several studies have investigated probiotic challenges in models of high-fat diet (HFD)-induced obesity, specifically with respect to its impact on hepatic and/or adipocyte metabolism, gut inflammation and epithelial barrier integrity, and microbiota composition. However, only a few studies have combined these aspects to generate a global understanding of how probiotics exert their protective effects. Here, we used the probiotic strain L. plantarum CNCM I−4459 and explored its impact on a mouse model of HFD-induced obesity. Briefly, mice were administered 1 × 109 CFUs/day and fed HFD for 12 weeks. Treatment with this strain improved insulin sensitivity by lowering serum levels of fasting glucose and fructosamine. Administration of the probiotic also affected the transport and metabolism of glucose, resulting in the downregulation of the hepatic Glut-4 and G6pase genes. Additionally, L. plantarum CNCM I−4459 promoted a decreased concentration of LDL-c and modulated hepatic lipid metabolism (downregulation of Fasn, Plin, and Cpt1α genes). Probiotic treatment also restored HFD-disrupted intestinal microbial composition by increasing microbial diversity and lowering the ratio of Firmicutes to Bacteroidetes. In conclusion, this probiotic strain represents a potential approach for at least partial restoration of the glucose sensitivity and lipid disruption that is associated with obesity.
Rates and processes of channel development and recovery following the 1980 eruption of Mount St. Helens, Washington

Abstract Stream channel development in response to the eruption of Mount St. Helens on 18 May 1980, resulted in some of the largest sediment yields documented anywhere on earth. Development of new channels on the 2.7 km3 debris-avalanche deposit in the North Fork Toutle River caused net erosion of as much as 1.3 x 105 t km−2 annually. Development of these channels followed a four-stage sequence of channel initiation, channel incision with relatively constant width-to-depth ratio, channel widening accompanied by aggradation, and channel widening accompanied by scour-and-fill with little change in average channel elevation. These channels remain unstable both in width and elevation. Lahars affected channel and valley morphology on all flanks of the volcano. Steep, upstream reaches generally incised and widened during the first year following the eruption and aggraded during the following three years. Gently sloping downstream reaches aggraded and widened during the first year and incised during the followin.
An experimental study of subaquaeous slipface deposition

ABSTRACT A flume study indicates that grainflow on slipfaces accounts for most cross-strata formed in unidirectional, shallow-water flows. The slipfaces studied were on small megaripples and delta-like steps (0.06-0.28 m high). During intermittent avalanching, at relatively low flow velocities, periods between avalanches were marked by grainfall onto the slipface, the intensity of which was greatest near the brink of the slipface and increased with current velocity. Nearly all grainfall deposits, however, were incorporated into subsequent grainflows. Grain flow cross-strata were made up of relatively distinct layers, at least near the base of the slipface. Continuous avalanching at high flow velocity was marked by a steady stream of grains forming more poorly defined cross-strata. Although the fundamental cause of grain flow is the gradual buildup of sediment on the upper slipface to the angle of initial yield, four other processes were recognized as promoting avalanching: 1) migration of superimposed bedforms to the brink, 2) generation of turbulent pulses upstream of the brink, 3) lee-eddy impingement on the lower slipface, and 4) extension of the lee eddy above the brink. The lee eddy proved very significant in slipface processes by redistributing grainfall sediments and both promoting and impeding grainflow. Regression analyses showed that the slipface advance per avalanche, Sa, is strongly correlated with the slipface height, H, expressed approximately by Sa = 0.060H. In addition, Sa is a direct function of the rate of slipface advance, Vb. The relationship among Sa, H, and Vb can be expressed as Sa/H = 0.0385[1 - 0.134 (min/cm) Vb]-1. Cross-strata dip angles between 28° and 34° show no systematic relation to H and Vb, but dip angles greater than 34° occurred only when both H and Vb were small, and dip angles less than 28° occurred only when both H and Vb were large.
Donor Deferral Pattern for Plateletpheresis at a Tertiary Care Teaching Hospital

: Single donor platelets has numerous advantages over Random Donor Platelets which includes decreased risk of Transfusion transmitted infections, bacterial contamination and alloimmunization due to reduce donor exposure. The most significant limitation to continued expansion of Plateletpheresis is the availability of platelet donors. Ineligibility of donors due to various reasons has further aggravated the already diminished pool of donors. On the basis of selection criteria, donors are deferred either temporarily or permanently. In our study 233 male donors were screened over one year out of which deferral rate was 44.2% (103 out of 233 donors). Deferral rate was highest in the age group of 25-34 years (45%) and most of these (73%) were replacement donors. Amongst these, 98.1% were deferred temporarily and 1.9% permanently. The most common cause of deferral was low platelet count (32%) followed by poor venous access (16%), URI/ intake of antibiotics (12%), low Hemoglobin levels (8%).
Sleep duration, cardiovascular disease, and proinflammatory biomarkers

: Habitual sleep duration has been associated with cardiometabolic disease, via several mechanistic pathways, but few have been thoroughly explored. One hypothesis is that short and/or long sleep duration is associated with a proinflammatory state, which could increase risk for cardiovascular and metabolic diseases. This hypothesis has been largely explored in the context of experimental sleep deprivation studies which have attempted to demonstrate changes in proinflammatory markers following acute sleep loss in the laboratory. Despite the controlled environment available in these studies, samples tend to lack generalization to the population at large and acute sleep deprivation may not be a perfect analog for short sleep. To address these limitations, population based studies have explored associations between proinflammatory markers and habitual sleep duration. This review summarizes what is known from experimental and cross-sectional studies about the association between sleep duration, cardiovascular disease, and proinflammatory biomarkers. First, the association between sleep duration with both morbidity and mortality, with a focus on cardiovascular disease, is reviewed. Then, a brief review of the potential role of proinflammatory markers in cardiovascular disease is presented. The majority of this review details specific findings related to specific molecules, including tumor necrosis factor-α , interleukins-1, -6, and -17, C-reactive protein, coagulation molecules, cellular adhesion molecules, and visfatin. Finally, a discussion of the limitations of current studies and future directions is provided.
Deduction of emissions of source gases using an objective inversion algorithm and a chemical transport model

An inversion algorithm, constructed to deduce the emissions of a source gas required to produce a specified surface concentration, is applied to the observed surface concentrations of CFC 11, methylchloroform, and methane, using a two-dimensional chemical transport model. The information utilized for this deduction process is limited to the measured atmospheric concentration of the source gas, including the associated standard deviations of these measurements. In this way the amount of objective information available in these measurements is assessed. The algorithm is shown to be capable of producing a latitudinal emissions distribution as well as the error bounds on the deduced emission distribution. The “ill posed” nature of this inverse problem is discussed as well as the implications this has on the spatial and temporal resolution at which emissions can be resolved. Finally, a methane emission distribution is deduced which has the expected seasonal variations and consistent with results from other, more subjective, deduction studies.
Winter transport and sea level fluctuations in Hecate Strait, British Columbia

Observed winter transport and adjusted sea level fluctuations in Hecate Strait were investigated using empirical orthogonal function and coherence analyses. The responses to large-scale and local wind forcings were identified by the distinctive spatial patterns of their adjusted sea level responses. At the resolved periods of 2 to 48 days, the large-scale and the local wind forcings were of roughly equal importance in driving transport fluctuations. Comparison of observations with a conceptual model indicates that the adjusted sea level in the northeast corner of the strait gives a good measure of response to both the local and large-scale wind forcings. This provides a physical explanation for the observed high correlation between the adjusted sea level at Prince Rupert and the winter transport fluctuations in Hecate Strait. We also show that the transport fluctuations are associated with a particular spatial pattern of the velocity field, which represents roughly 1/4 of the energy in the observed winter velocity fluctuations measured at an array of current meters. This has implications for the use of surrogate transport series to hindcast oceanographic conditions in Hecate Strait.
Diversidade genética entre cultivares de mangueiras, baseada em caracteres de qualidade dos frutos

Genetic diversity among cultivars of mango based on fruit quality traits The mango crop is one of the most significant agribusiness in Brazil. Although there are many cultivars, cultivation has been done primarily with ‘Tommy Atkins’ and there are few studies on characterization and analysis of genetic diversity in different areas of production. Therefore, the objective of this work was to study the genetic diversity of fifteen mango cultivars, eight from Brazil and seven from Florida (USA), produced in the Zona da Mata Mineira region. Fifteen ripe fruits from each cultivar were collected and analyzed chemically and physically . The cultivars that showed more similarities were ‘Kent’ and ‘Palmer’. ‘Extrema’ was not grouped with the others by the UPGMA clustering method. This analysis was also used for the separation of Brazilian and USA cultivars. The principal component analysis of the chemical characteristics did not group the cultivars ‘Extrema’ and ‘Tommy Atkins’ with the others. The physical characteristics showed the same separation obtained by the UPGMA method, except for the cultivar ‘Extrema’ that was grouped with other cultivars. There was correlation between the color of the pulp, hue angle, and total soluble sugar content and between the color of the peel, b* index and percentage of peel and pulp.
A shift in the spatial pattern of Iberian droughts during the 17th century

Abstract. In this paper, series of drought occurrence and drought extension in the Iberian Peninsula are constructed for the 1600–1750 period from seven rogation series. These rogation ceremony records come from Bilbao, Catalonia, Zamora, Zaragoza, Toledo, Murcia and Seville. They are distributed across the Peninsula and include the areas with the most characteristic Iberian climate types, influenced by the Atlantic and the Mediterranean conditions, described from modern data. A seasonal division of the series shows that spring is a critical season for rogation series in most of Iberia, being Bilbao the only site were the highest number of rogations is detected for a different season. The annual analysis of the series shows a dramatic difference between the first half of the 17th century when droughts are characterized by its local character; and the rest of the period, when they affect to broader regions or even to the whole Peninsula. The analysis of spring series confirms the existence of the two periods detected in the annual analysis. Finally, secondary documentary sources are used to further characterise the two most extended droughts in the period, 1664 and 1680, and to verify the extension of the areas affected by droughts recorded through rogation series.
Self-regulated learning and personality in university students

The present investigation analyzes the relationship between the self-regulation of learning and the personality characteristics of university students belonging to the Minuto de Dios University Corporation - UNIMINUTO of Bogotá - Colombia the sample consisted of 75 men and women between 18 and 45 years of age. From the application of the instruments: Gordon's personality profile and inventory (ancestry, responsibility, emotional stability, sociability, caution, originality, commitment, vitality, and self-esteem) and the self-report questionnaire - self-regulation of learning, the correlational analysis was carried out. Using Spearman's Rho (significance level p<0.05). The results suggest that students who know and apply learning self-regulation techniques tend to be dominant (ancestry) independent, so they take responsibility for their personal goals (commitment), emotionally stable, and friendly. On the other hand, students who are cautious, original, and oriented towards understanding others tend to give little importance or use, to a lesser extent, the use of self-regulated learning strategies.
Effects of flow alteration on Apple‐ring Acacia (Faidherbia albida) stands, Middle Zambezi floodplains, Zimbabwe

The impounding of the Zambezi River by Kariba dam has regulated the river discharge of the Middle Zambezi river. This has been implicated in the failure of regeneration of Faidherbia albida in the downstream flood plain. This study aimed (1) to assess the effect of the altered flow regime of the river on the establishment and growth of F. albida on the Middle Zambezi floodplain and islands and (2) to test the potential of dendrochronology in detecting the age and long‐term growth rates of F. albida in response to flow regime.
Susceptibilidad de Chrysopa exterior Navás a Beauveria bassiana (Balsamo) Vuillemin cepa LBB-1 en condiciones

espanolEl uso de la lucha biologica para el control de plagas que afectan a los cultivos se ha generalizado en todo el pais debido a sus multiples ventajas en el ambito economico, ecologico y social. Dentro de las estrategias de control biologico se emplean diversos medios como el hongo entomopatogeno Beauveria bassiana (Balsamo) Vuillemin, y el depredador Chrysopa exterior Navas. Para su utilizacion conjunta se debe pasar por una etapa previa, imprescindible para establecer los posibles efectos negativos de su interaccion mediante bioensayos ecotoxicologicos. En este trabajo se evaluo la susceptibilidad de las distintas fases de desarrollo del depredador C. exterior al hongo entomopatogeno B. bassiana en condiciones de laboratorio. Se utilizaron insectos obtenidos de una cria de laboratorio de C. exterior y suspensiones a base de la cepa LBb-1 a las concentraciones de 1 x 107 y 1 x 108 esporas � mL�1. Los bioensayos se realizaron bajo condiciones de temperatura de 25 ± 1°C y humedad relativa del 80 ± 2%. Los estados preimaginales del entomofago fueron sumergidos en las suspensiones, y los adultos se asperjaron. El parametro evaluado en los huevos fue su eclosion. En las larvas y los adultos la mortalidad, y para los cocones la emersion de los adultos. Las suspensiones conidiales del hongo no afectaron ninguna de las fases de desarrollo del insecto, por lo que ambos controles biologicos pueden utilizarse conjuntamente para el control de plagas agricolas en los sistemas de produccion EnglishThe use of biological control for reducing plagues of crops has extended in the whole country, due to the numerous advantages that it brings in economic, ecological and social aspects. Diverse means as entomopathogenic fungus Beauveria bassiana (Balsamo) Vuillemin and the predator Chrysopa exterior Navas are used inside biological control strategies. For the combined use it should pass through an indispensable previous stage in order to establish the possible negative effects of their interaction by means ecotoxicological studies. In this way this work was realized to evaluate the different development phases susceptibility of predator C. exterior to the entomopathogenic fungus B. bassiana in ecotoxicological bioassays under laboratory conditions. Insects obtained from a laboratory breeding of C. exterior and suspensions of strain LBb-1 at concentrations of 1 x 107 and 1 x 108 spores � mL�1 were used. Assays were made at temperature of 25 ± 1°C and 80 ± 2% of relative humidity. Immature states of natural enemies were submerged in suspensions and the adults were sprayed. The parameter evaluated in eggs was its appearance, mortality was evaluated in larvae, and adults emergency were evaluated in pupae. LBb-1 strain suspensions did not affect any development phases of insect, so both biological controls can be used together for agricultural pest control in production systems
Mudstone compaction curves in basin modelling: a study of Mesozoic and Cenozoic Sediments in the northern North Sea

Basin modelling studies are carried out in order to understand the basin evolution and palaeotemperature history of sedimentary basins. The results of basin modelling are sensitive to changes in the physical properties of the rocks in the sedimentary sequences. The rate of basin subsidence depends, to a large extent, on the density of the sedimentary column, which is largely dependent on the porosity and therefore on the rate of compaction. This study has tested the sensitivity of varying porosity/depth curves and related thermal conductivities for the Cenozoic succession along a cross‐section in the northern North Sea basin, offshore Norway. End‐member porosity/depth curves, assuming clay with smectite and kaolinite properties, are compared with a standard compaction curve for shale normally applied to the North Sea. Using these alternate relationships, basin geometries of the Cenozoic succession may vary up to 15% from those predicted using the standard compaction curve. Isostatic subsidence along the cross‐section varies 2.3–4.6% between the two end‐member cases. This leads to a 3–8% difference in tectonic subsidence, with maximum values in the basin centre. Owing to this, the estimated stretching factors vary up to 7.8%, which further gives rise to a maximum difference in heat flow of more than 8.5% in the basin centre. The modelled temperatures for an Upper Jurassic source rock show a deviation of more than 20 °C at present dependent on the thermal conductivity properties in the post‐rift succession. This will influence the modelled hydrocarbon generation history of the basin, which is an essential output from basin modelling analysis. Results from the northern North Sea have shown that varying compaction trends in sediments with varying thermal properties are important parameters to constrain when analysing sedimentary basins.
Cultivation Of Winter Garlic Under Conditions Of The Left-Bank Forest-Steppe Of Ukraine And Molecular And Genetic Polymorphism Of Winter Garlic Varieties By Issr Loci

In Ukraine, there is a tendency to increase the area of garlic, which is due to the high profitability of its production and constant demand in both domestic and foreign markets. The increase in the volume of this crop production occurs mainly due to an increase in the area and not due to an increase in cropping capacity. The reason for the slow growth in the cropping capacity of winter garlic is the limited possibilities of seed production of the crop and low adaptability to growing conditions, caused by the vegetative type of reproduction, which leads to a limited production area of the varieties which had been created by this time. For this reason, mainly local garlic varieties are grown in Ukraine and abroad, which are well adapted to the ecological conditions of the region. Based on this, for the further growth of garlic production, both for the Left-Bank Forest-Steppe zone and for the whole of Ukraine, the assessment of existing and new varieties of this crop is important. The aim of conducted studies was to assess the genetic diversity of winter garlic varieties selected for research by ISSR loci and determine the most productive of them under conditions of the Left-Bank Forest-Steppe of Ukraine. The study was conducted with winter garlic varieties Duchess, Lubasha and Hungarian (line 20-16). On average, during the three years of research, the highest level of commercial cropping capacity was observed in Lubasha variety (14.1 t/ha), in Hungarian variety 12.9 t/ha and 9.4 t/ha in Duchess variety (control variant). Formation of winter garlic cropping capacity by 12.3% depended on the peculiarities of the variety, the influence of growing season conditions was 87.3 %, the combined effect of AB factors was not significant, its share in cropping capacity variability was only 0.5 %. Agronomically stable was Hungarian winter garlic variety with As = 73.8 %. In the studied varieties of winter garlic, several amplicons were found that are unique within the studied group. Duchess variety had unique loci UBC 812 725 and UBC 812 902 , while Lubasha variety had unique loci UBC 812 791 and UBC 842 702 . Hungarian variety (line 20-16) had a bigger number of unique loci: UBC 812 460 , UBC 812 997 UBC 826 682 , UBC 834 1283 and UBC 846 920 The calculated Nei-Li similarity coefficients indicate a significant genetic similarity of the studied winter garlic varieties. Lubasha and Duchess varieties are genetically closer to each other, compared to Hungarian variety.
Overview of the Discovery, Distribution, and Geological Context of Simosuchus clarki (Crocodyliformes: Notosuchia) from the Late Cretaceous of Madagascar

ABSTRACT Simosuchus clarki is a bizarre, pug-nosed notosuchian crocodyliform known only from the Upper Cretaceous (Maastrichtian) Maevarano Formation in the Mahajanga Basin of northwestern Madagascar. When originally named and described in 2000, S. clarki was based entirely on a single specimen that included a nearly complete skull and lower jaw preserved in articulation with the anterior and mid-trunk portions of the postcranial skeleton, as well as several associated elements from the posterior region. The species is now represented by three additional partial and nearly complete articulated skeletons, as well as numerous isolated elements (mostly teeth), that permit detailed description of its entire bony anatomy, the primary subject of other chapters in this volume. These specimens were discovered as part of the ‘Mahajanga Basin Project,’ initiated in 1993 and conducted jointly by Stony Brook University and the Université d'Antananarivo, in the Berivotra and Masiakakoho study areas. The best-preserved specimens of S. clarki were entombed in massive, poorly sorted, clay-rich debris flow deposits (facics 2 of the Anembalemba Member) that accumulated in channel belts in response to exceptional rainfall events. Simosuchus, along with its contemporaries in the Maevarano assemblage, lived in a strongly seasonal, semi-arid climate some 20 million years after Madagascar separated from the India/Seychelles block and became an island isolated in the Indian Ocean.