Miracle-dz/UniFAR-FTUs huggingface dataset:
Plasma amylin concentration in suckling goat neonates and its relationship with C-reactive protein, selected biochemical and hormonal indicators

Amylin is a recently discovered neuropeptide hormone that belongs to the calcitonin generelated peptide family. It is co-secreted with insulin in response to feed intake. In goat kids, neonatal mortality and morbidity seems to be relatively higher than in other farm species. This high mortality and morbidity in goat kids may be associated with underdeveloped metabolism and immune system during the first week of life. The main objectives of this study were to determine amylin concentration and its relationship with some hormones, biochemical indicators and with a general inflammatory marker, CRP (C-reactive protein) in goat neonates. Blood samples were collected from 30 Saanen goat neonates at 20–35 days of age. Plasma amylin and other hormone concentrations were measured by ELISA, whereas serum biochemical indices were analysed by spectrophotometry. The mean values of plasma amylin concentrations were 9.07 ± 0.25 pmol/l. Plasma amylin concentrations were positively correlated with plasma non-esterified fatty acids, CRP, prolactin, cortisol, insulin; however, a negative correlation was determined between plasma amylin and serum triglyceride concentrations. The current study suggests that amylin contents are strongly associated with circulating concentrations of some hormones and with those of CRP in Saanen goat kids.
Explainable Rumor Detection using Inter and Intra-feature Attention Networks

With social media becoming ubiquitous, information consumption from this media has also increased. However, one of the serious problems that have emerged with this increase, is the propagation of rumors. Therefore, rumor identification is a very critical task with significant implications to economy, democracy as well as public health and safety. We tackle the problem of automated detection of rumors in social media in this paper by designing a modular explainable architecture that uses both latent and handcrafted features and can be expanded to as many new classes of features as desired. This approach will allow the end user to not only determine whether the piece of information on the social media is real of a rumor, but also give explanations on why the algorithm arrived at its conclusion. Using attention mechanisms, we are able to interpret the relative importance of each of these features as well as the relative importance of the feature classes themselves. The advantage of this approach is that the architecture is expandable to more handcrafted features as they become available and also to conduct extensive testing to determine the relative influences of these features in the final decision. Extensive experimentation on popular datasets and benchmarking against eleven contemporary algorithms, show that our approach performs significantly better in terms of F-score and accuracy while also being interpretable.
Analysis of lactation feed intakes for sows with extended lactation lengths

Abstract The objectives of this research were to quantify and model daily feed intakes to 28 d of lactation in modern sows. A total of 4,512 daily feed intake (DFI) records were collected for 156 Hypor sows from February 2015 to March 2016. The mean lactation length was 27.9 ± 2.0 d. The data included 9 parity 1, 33 parity 2 and 114 parity 3+ sows. Data were collected using a computerized feeding system (Gestal Solo, JYGA Technologies, Quebec, Canada). The feeding system was used to set an upper limit to DFI for the first 7 d of lactation. Overall, the least-squares means of a model including the random effect of sow indicated that DFI's continued to slowly increase to 28 d of lactation. The DFI data were fitted to Generalized Michaelis-Menten (GMM) and polynomial functions of day of lactation (t). The GMM function [DFIi,t (kg/d) = DFI0 + (DFIA − DFI0)(t/K)C/[1 + (t/K)C]] was fitted with 2 random effects for DFI (dfiAi) and intercept (dfi0i) using the NLMIXED procedure in SAS®. The polynomial function DFIi,t (kg/d) = [B0 + B1 t + B2 t2 + B3 t3 + B4 t4] was fitted with three random effects for B0, B1, and B2 using the MIXED procedure in SAS®. Fixed effects models of the two functions had similar Akaike's Information Criteria (AIC) values and mean predicted DFI's. The polynomial function with 3 random effects provided a better fit to the data based on R2 30 (0.81 versus 0.79), AIC (14,709 versus 15,158) and RSD (1.204 versus 1.321) values than the GMM function with two random effects. The random effect for B2 in the polynomial function allowed for the fitting of the function to lactation records that had decreased DFI after 15 d of lactation. The random effects for the polynomial function were used to sort the lactation records into three groups based on the derivative of the function at 21 d of lactation. Lactation records of the three groups had similar DFI the first two weeks of lactation (P > 0.40). The three groups of sows had substantially different DFI's after 18 d of lactation (P < 0.028). The differences in both actual and predicted DFI's between the three groups increased with each day of lactation to day 28 (P < 0.001). Mixed model polynomial functions can be used to identify sows with different patterns of DFI after 15 d of lactation.
What Works in Mindfulness Interventions for Medically Unexplained Symptoms? A Systematic Review

Abstract Background/Purpose: Mindfulness-based interventions (MBIs) have been used in medically unexplained symptoms (MUS). This systematic review describes the literature investigating the general effect of MBIs on MUS and identifies the effects of specific MBIs on specific MUS conditions. Methods: The Preferred Reporting Items for Systematic Reviews and Meta-Analysis Guidelines (PRISMA) and the modified Oxford Quality Scoring System (Jadad score) were applied to the review, yielding an initial 1,556 articles. The search engines included PubMed, ScienceDirect, Web of Science, Scopus, EMBASE, and PsychINFO using the search terms: mindfulness, or mediations, or mindful or MBCT or MBSR and medically unexplained symptoms or MUS or Fibromyalgia or FMS. A total of 24 articles were included in the final systematic review. Results/Conclusions: MBIs showed large effects on: symptom severity (d = 0.82), pain intensity (d = 0.79), depression (d = 0.62), and anxiety (d = 0.67). A manualized MBI that applies the four fundamental elements present in all types of interventions were critical to efficacy. These elements were psycho-education sessions specific to better understand the medical symptoms, the practice of awareness, the nonjudgmental observance of the experience in the moment, and the compassion to ones’ self. The effectiveness of different mindfulness interventions necessitates giving attention to improve the gaps that were identified related to home-based practice monitoring, competency training of mindfulness teachers, and sound psychometric properties to measure the mindfulness practice.
Bacterial quality control of domestic and imported brands of bottled water in Saudi Arabia

Water is one of the most abundant and essential commodities of man occupying about 70% of the earth’s surface and 60% of the human body therefore it should be continuously protected against microbial infections. Also, the mineral content in drinking water should be maintained within the acceptable range. Quality control of drinking water emerged with the invention of bottled drinking water. In this study, samples of bottled drinking water from Saudi markets were compared with tap water samples collected from different areas in Riyadh; both samples were tested for the presence of pathogenic bacteria. The bacterial isolates identified by the Biolog system (Hayward, CA, USA) include Bacillus cereus, Staphylococcus sp. and Pseudomonas aeruginosa in bottled drinking water, whereas tap water was mainly contaminated by P. aeruginosa. Bacterial contamination was highly observed in tap water samples and higher mineral content, determined by inductively coupled plasma-mass spectrometry (ICPMS) was also observed in tap water. Bacterial cell count determined as CFU/ml was observed in bottled drinking water. Decreased water bacterial number was achieved with the solar disinfection system (SODIS) for one day with direct exposure to sunlight in polyethylene terephthalate (PET) plastic bottles. Thus water considered to be consumed by humans must maintain good microbial and mineral qualities within the acceptable ranges and must undergo effective treatment in order to reduce bacterial count and infection.
Nymph and Adult Performance of the Small Green Stink Bug, Piezodorus guildinii (Westwood) on Lanceleaf Crotalaria and Soybean

Lanceleaf crotalaria, Crotalaria lanceolata E. Mey (Leguminosae) was found hosting the small green stink bug, Piezodorus guildinii (Westwood), in Parana State, Brazil. In the laboratory, nymphs showed less mortality when fed on immature pods of crotalaria (64%) than when fed on immature pods of soybean, Glycine max (L.) Merrill (88%). From 2nd stadium to adult, nymphs required less time to complete development on crotalaria (mean of females and males = 18.4 days) than on soybean (21.5 days). Fresh body weight at adult emergence was greater on crotalaria (mean of females and males = 51.4 mg) than on soybean (42.2 mg). Adult P. guildinii tended to live longer on crotalaria than on soybean. Mean adult longevity was 34.6 days on crotalaria, and 28.8 days on soybean. However, the reproductive performance of females, although similar on both foods, tended to be greater on soybean. These results indicated that P. guildinii was able to develop and reproduce on the wild host lanceleaf crotalaria. Compared to soybean, this weed plant was more suitable for nymph development, and equally suitable for adult reproduction.
Transcriptome analysis reveals a reprogramming energy metabolism-related signature to improve prognosis in colon cancer

Although much progress has been made to improve treatment, colon cancer remains a leading cause of cancer death worldwide. Metabolic reprogramming is a significant ability of cancer cells to ensure the necessary energy supply in uncontrolled proliferation. Since reprogramming energy metabolism has emerged as a new hallmark of cancer cells, accumulating evidences have suggested that metabolism-related genes may serve as key regulators of tumorigenesis and potential biomarkers. In this study, we analyzed a set of reprogramming energy metabolism-related genes by transcriptome analysis in colon cancer and revealed a five-gene signature that could significantly predict the overall survival. The reprogramming energy metabolism-related signature could distinguish patients into high-risk and low-risk groups with significantly different survival times (P = 0.0011; HR = 1.92; 95% CI [1.29–2.87]). Its prognostic value was confirmed in another two independent colon cancer cohorts (P = 5.2e–04; HR = 2.09, 95%; CI [1.37–3.2] for GSE17538 and P = 3.8e−04; HR = 2.08, 95% CI [1.37–3.16] for GSE41258). By multivariable analysis, we found that the signature was independent of clinicopathological features. Its power in promoting risk stratification of the current clinical stage was then evaluated by stratified analysis. Moreover, the signature could improve the power of the TNM stage for the prediction of overall survival and could be used in patients who received adjuvant chemotherapy. Overall, our results demonstrated the important role of the reprogramming energy metabolism-related signature in promoting stratification of high-risk patients, which could be diagnostic of adjuvant therapy benefit.
Many Factors Influence the Evolution of Herbivore Diets, But Plant Chemistry is Central

There is little question that predators, as well as many other factors, influence dietary evolution in phytophagous arthropods (Southwood 1973). Brower (1958) outlined elegantly the role of generalist predators almost 30 yr ago. Although Bernays and Graham cite several recent theoretical discussions, there really has been little experimental work. As a consequence, Bernays and Graham decry an "overemphasis" on host plant chemistry. It is important to remember that in 1964 Ehrlich and Raven correctly identified an underemphasis on plant chemistry. Recognition of this underemphasis created a subdiscipline and allowed ecologists to appreciate interactions and phenomena that were missed entirely before their chemical basis was clear. Although it is true that the ensuing enthusiasm for chemical ecology has exceeded that for other influences on dietary evolution, I cannot agree that plant chemistry should receive reduced attention, or that it is less important than we thought. Its importance remains under-appreciated and demands increased study. In this essay I outline why this is so, and suggest that this view is fully consistent with giving natural enemies more attention.
Comparative Effectiveness Study of Home-Based Interventions to Prevent CA-MRSA Infection Recurrence

BACKGROUND: Recurrent skin and soft tissue infections (SSTI) caused by Community-Associated Methicillin-Resistant (CA-MRSA) or Methicillin-Sensitive Staphylococcus aureus (CA-MSSA) present treatment challenges. OBJECTIVES: Can an evidence-based intervention (CDC Guidelines, topical decolonization, surface decontamination) reduce SSTI recurrence, mitigate household contamination and transmission, and improve patient-reported outcomes? DESIGN: Randomized trial SETTING: Community settings PARTICIPANTS: Participants (n=186) with confirmed MRSA(+)/MSSA(+) SSTIs and household members. INTERVENTION Community Health Workers/Promotoras conducted home visits and provided participants with instructions, a five-day supply of mupirocin for nasal application, chlorhexidine for body cleansing, and disinfecting wipes for household cleaning (EXP) versus Usual Care (UC). MEASUREMENTS: Primary outcome was six-month SSTI recurrence recorded in electronic health records (EHR). Home visits (months 0/3) and telephone assessments (months 0/1/6) collected self-report data. Surveillance culture swabs (nares, axilla, groin) were obtained from index patients and participating household members. Secondary outcomes included household surface contamination, household member colonization and transmission, quality of life and satisfaction with care. RESULTS: Among patients with SSTIs (n=421), 44.2% were MRSA(+)/MSSA(+); an intent-to-treat analyses (n=186) demonstrated no significant differences in SSTI recurrence (OR: 1.4, 95% CI: 0.51-3.5). Among the enrolled cohort (n=119), there were no significant SSTI recurrence effects (OR=1.14, 95% CI=0.35-3.6). EXP participants showed reduced but non-significant colonization rates. There were no differential reductions in household member transmission or in reductions in proportions of households with >1 contaminated surface. Mupirocin resistance did not increase. No significant improvements for patient-reported outcomes were seen. LIMITATIONS: A lower-than-predicted six-month recurrence rate may have limited the ability to detect effects. CONCLUSION: This intervention did not reduce clinician-reported MRSA/MSSA SSTI recurrence. No differences were observed for household members decolonization or household surfaces decontamination.
Determine Factors of NFC Mobile Payment Continuous Adoption in Shopping Malls: Evidence From Indonesia

Near Field Communication (NFC) mobile payment systems allow users to utilize services through smartphones. There is insufficient literature exploring the adoption of NFC with payment scenarios in developing countries. This study aims to explore the influential factors of consumer adoption of NFC, taking payment behaviors through NFC in Indonesia as an example. One hundred forty-seven participants were enrolled in the 5-point Likert scale survey, and 124 valid samples were analyzed with Partial Least Squares Structural Equation Modeling (PLS-SEM). The results show that trust mediates the effect of context on consumers' continuous intention to use NFC mobile payment. Additionally, trust mediates the effect of perceived risk on consumers' continuous intention to use. The perceived ease of use and perceived usefulness have no effects on consumers' continuous intention to use. The mediating effect of religiosity has not been observed in this study. The findings can enbale service providers and local governments to offer better mobile payment services.
Epidemiologic, clinical and biological characteristics of adult T-cell leukemia/lymphoma in Martinique (1983-2013)

We report one of the largest non-Japanese cohorts of adult T-cell leukemia/lymphoma (ATL). A total of 175 cases were identified in Martinique between 1983 and 2013. The sex ratio was 1.01. The median age was 56 years. The overall incidence rate was 1.16/105 inhabitants/year, with a risk 1.29 times higher for men. The distribution of clinical types (acute, lymphoma, and chronic) was 62.9%, 29.1%, and 8%, respectively. Median survival time was 3.06, 8.13, and 45.16 months, respectively, for the acute, lymphoma, and chronic types (p <0.001). Survival was significantly higher for lymphoma type with skin lesions (median 13.96 months versus 6.06, p <0.002) and for the acute type without hypercalcemia (5.1 versus 2.4 months, p <0.01). Symptoms associated with hypercalcemia present in 46.9% of patients and skin lesions in 43.4% were the best-performing clinical signs for the diagnosis of ATL. However, only 16.9% had these manifestations. Strongyloides stercoralis infection was documented in 42.5% of patients. Twenty-three patients had an atypical phenotype, including 14 cases with CD4-CD8- and 4 with CD4+CD8+. Twenty-four patients did not express CD25 with no significant impact on overall survival. The hyperploidy, trisomy of chromosome 3 and rearrangements of chromosome 14 were the most frequent karyotype abnormalities. Keywords: HTLV-1, ATL, epidemiology of ATL, phenotype of ATL cell, karyotype of ATL cell.
Four-Level Forms for Memristive Material Implication Logic

This brief proposes the use of four-level forms in the memristive material implication (M-IMP) logic. M-IMP is a promising approach to perform stateful logic in memristive nonvolatile memories. In such a design technique, a given Boolean function is evaluated as a sequence of instructions, making logic synthesis methods necessary to attain the shortest sequence. In comparison to previous work, experimental results have shown an average reduction of 40% when evaluating the tradeoff between the numbers of instructions and memristive devices.
Powered knee and ankle prosthesis with indirect volitional swing control enables level-ground walking and crossing over obstacles

Control of prosthesis swing trajectory enables individuals to voluntarily change foot clearance to traverse obstacles. Powered prostheses aim to mimic the missing biological limb with controllers that are finely tuned to replicate the nominal gait pattern of non-amputee individuals. Unfortunately, this control approach poses a problem with real-world ambulation, which includes tasks such as crossing over obstacles, where the prosthesis trajectory must be modified to provide adequate foot clearance and ensure timely foot placement. Here, we show an indirect volitional control approach that enables prosthesis users to walk at different speeds while smoothly and continuously crossing over obstacles of different sizes without explicit classification of the environment. At the high level, the proposed controller relies on a heuristic algorithm to continuously change the maximum knee flexion angle and the swing duration in harmony with the user’s residual limb. At the low level, minimum-jerk planning is used to continuously adapt the swing trajectory while maximizing smoothness. Experiments with three individuals with above-knee amputation show that the proposed control approach allows for volitional control of foot clearance, which is necessary to negotiate environmental barriers. Our study suggests that a powered prosthesis controller with intrinsic, volitional adaptability may provide prosthesis users with functionality that is not currently available, facilitating real-world ambulation.
Xp11 translocation renal cell carcinoma with morphological features mimicking multilocular cystic renal neoplasm of low malignant potential: a series of six cases with molecular analysis

Aims Xp11 translocation renal cell carcinoma (RCC) is a distinctive subtype of RCC with TFE3 (Transcription Factor Binding to IGHM Enhancer 3) gene rearrangement. The gross features in most Xp11 translocation RCCs closely resemble clear cell RCCs. In this study, we report six cases of Xp11 translocation RCCs with a unique multicystic architecture, reminiscent of multilocular cystic renal cell neoplasm of low malignant potential (MCRN-LMP). Methods and results Microscopically, the renal mass was well circumscribed with multilocular cystic architecture. The cyst walls and septa were mostly lined by a single layer of cells with clear cytoplasm and low-grade nuclei, reminiscent of MCRN-LMP. Psammoma bodies were detected in four cases. One particular patient was misdiagnosed with benign cysts in local hospitals and led to second operation. Tumour cells were settled according to the track of the first surgical procedure. TFE3 fluorescence in situ hybridization (FISH) assay confirmed the diagnosis of Xp11 translocation RCCs. FISH and RNA sequencing analyses confirmed MED15-TFE3 gene fusion in all six cases. Respective patients were alive, without any recent evidence of disease recurrence and/or metastasis. Conclusions Here, we introduce a relatively inertia-variant of Xp11 translocation RCC which mimics MCRN-LMP. The distinctive morphological condition is linked to MED15-TFE3 gene fusion. In fact, renal neoplasms with morphological features of MCRN-LMP, especially those containing psammoma bodies, should be routinely evaluated for evidence of TFE3 gene rearrangements.
Adenosine deaminase activity and peripheral immune cells ratios in a sample of inflammatory bowel disease patients

Seventy inflammatory bowel disease (IBD) patients (35 ulcerative colitis; UC and 35 Crohn's disease; CD) and 20 controls were investigated for serum level of adenosine deaminase (ADA) and neutrophil-lymphocyte and monocytelymphocyte ratios. The results revealed that the mean of ADA was significantly increased in UC and CD patients (46.72 ± 8.99 and 41.17 ± 5.95 ng/ml, respectively) compared to controls (20.85 ± 2.79 ng/ml), but it was also significantly higher in UC patients than in CD patients. The neutrophillymphocyte ratio mean was also significantly increased UC patients (5.83 ± 3.10) as compared to CD patients (3.79 ± 2.02) or controls (1.66 ± 0.22). The ratio was also significantly increased in CD patients compared to controls. A similar pattern was also observed in monocyte-lymphocyte ratio. In conclusion ADA may have a role in the pathogenesis of IBD, especially UC, and consequently the peripheral immune cells might have been affected. Date Submitted:8/2/2015 Date Accepted:4/5/2015 Address for Correspondence: Sahar Manfi Ahmad, Al-Rafidain Universiy College