Miracle-dz/UniFAR-FTUs huggingface dataset:
Machine Learning for Early Prediction of Major Adverse Cardiovascular Events After First Percutaneous Coronary Intervention in Patients With Acute Myocardial Infarction: Retrospective Cohort Study

Background The incidence of major adverse cardiovascular events (MACEs) remains high in patients with acute myocardial infarction (AMI) who undergo percutaneous coronary intervention (PCI), and early prediction models to guide their clinical management are lacking. Objective This study aimed to develop machine learning–based early prediction models for MACEs in patients with newly diagnosed AMI who underwent PCI. Methods A total of 1531 patients with AMI who underwent PCI from January 2018 to December 2019 were enrolled in this consecutive cohort. The data comprised demographic characteristics, clinical investigations, laboratory tests, and disease-related events. Four machine learning models—artificial neural network (ANN), k-nearest neighbors, support vector machine, and random forest—were developed and compared with the logistic regression model. Our primary outcome was the model performance that predicted the MACEs, which was determined by accuracy, area under the receiver operating characteristic curve, and F1-score. Results In total, 1362 patients were successfully followed up. With a median follow-up of 25.9 months, the incidence of MACEs was 18.5% (252/1362). The area under the receiver operating characteristic curve of the ANN, random forest, k-nearest neighbors, support vector machine, and logistic regression models were 80.49%, 72.67%, 79.80%, 77.20%, and 71.77%, respectively. The top 5 predictors in the ANN model were left ventricular ejection fraction, the number of implanted stents, age, diabetes, and the number of vessels with coronary artery disease. Conclusions The ANN model showed good MACE prediction after PCI for patients with AMI. The use of machine learning–based prediction models may improve patient management and outcomes in clinical practice.
Relationship between Hope and Quality of Life in Patients with Advanced Cancer in Uruguay: An Observational Analysis

Introduction: International research suggests a beneficial effect of hope on quality of life in advanced-stage cancer patients. Specific evidence for Latin America and Uruguay is limited, highlighting the need to explore this relationship for regional clinical strategies.Objective: To evaluate the correlation between hope and quality of life in Uruguayan patients with advanced cancer. Materials and Methods: This observational, analytical-descriptive, and cross-sectional study used the Herth Hope Index (HHI) and the Functional Assessment of Cancer Therapy - General (FACT-G) Quality of Life questionnaire. It included 59 patients aged 18 or older, diagnosed with advanced, non-curable cancer.
What Do Students Find Relevant in an Introductory Geology Course? Implications for Changing Students' Attitudes About the Relevance of Geoscience in Society.

SMITH, HAYLEY JOYELL. What do Students Find Relevant in an Introductory Geology Course? Implications for Changing Students’ Attitudes About the Relevance of Geoscience in Society. (Under the direction of Dr. David McConnell.) Geoscience education plays a vital role in achieving the goal of cultivating a scientifically literate citizenry that can make informed decisions for a sustainable future. This study investigated undergraduates’ attitudes about and perceptions of the relevance of geoscience in society. Using a mixed-methods approach, data were collected over the course of a semester in an active-learning introductory geology courses. Course structure, instructor pedagogical practices and student demographic profile characteristics were described. Students’ (n=144) attitudes in three section of MEA 101 were quantitatively measured with the Changes in Attitudes about the Relevance of Science (CARS) instrument. There was no significant difference in students’ attitudes about the relevance of science among sections. Statistical analysis provided evidence that student’s average CARS scores significantly increased (p=0.018) over the course of the semester. This signified that students were increasingly more agreeable to statements about the application of science in daily decisionmaking. Students’ change in CARS scores showed a significant positive relationship with two of the three performance measures. The strongest relationship (R=0.16, p<0.001) was with a short-answer score that assessed students’ ability to describe the application of geoscience content in society. Qualitative data from open-ended questions provided insight into students’ perceptions of the relevance of geoscience in society. Analysis of responses showed that students identified similar geoscience concepts relevant to society as described by the Earth Science Literacy Principles human-Earth related Big Ideas. These concepts included topics related to natural hazards, water and energy resources, and climate change. Student responses revealed the link between perception of relevance and application of the geoscience content in a real-world situation. © Copyright 2013 Hayley Joyell Smith All Rights Reserved What do Students Find Relevant in an Introductory Geology Course? Implications for Changing Students’ Attitudes About the Relevance of Geoscience in Society by Hayley Joyell Smith A thesis submitted to the Graduate Faculty of North Carolina State University in partial fulfillment of the requirements for the degree of Master of Science Marine, Earth & Atmospheric Sciences Raleigh, North Carolina 2014
Peripheral Blood Smear Analysis for Cattle with Foot and Mouth Diseases in Lembang, West Bandung

Foot and Mouth Disease (FMD) is an infectious disease that is endemic and has a significant impact on dairy farming in Indonesia. In reducing the impact caused by FMD, proper handling by veterinarians is necessary. The peripheral blood smear can be used as a data reference to give priority to the right treatment for cattle with FMD. This study aimed to describe the appearance of peripheral blood smears in cattle with FMD. The study data were obtained from 15 cattle with FMD at KPSBU Lembang, West Bandung, West Java, Indonesia. The morphological profile of the blood was examined using the peripheral blood smear method. Morphological abnormalities found in the peripheral blood smear of red blood cells were anisocytosis (microcytosis and macrocytosis), poikilocytosis (achanthocytosis and echinocytosis), and hypochromasia. Different morphological abnormalities of leukocytes can be caused by anorexia due to FMD secondary to lack of nutritional intake. To determine an effective and efficient treatment, it is recommended that veterinarians refer to the results of this study.
Bank Credit and Economic Growth: Evidence from OIC Countries

This study aims to explore the impact of bank credit along with three other independent variables, namely population, employment, and inflation, on economic growth in 55 Organization of Islamic Cooperation (OIC) member countries. The data used is annual panel data from 2010 to 2021, obtained from SESRIC OIC. The analysis method applied in this study is static panel data regression. The results show that each independent variable, such as population, employment, inflation, and total bank credit, has a significant effect both simultaneously and partially on the economic growth variable (GDP). Bank credit facilitates the efficient allocation of resources from savers to borrowers who have productive investment opportunities, thereby promoting economic growth. Second, banks act as an important channel in the transmission of monetary policy by providing financial intermediation, receiving and utilizing large amounts of public funds, and creating money supply. Third, bank credit expansion is associated with higher economic growth across industries, encouraging tangible investment but not intangible investment in more debt-dependent industries.
Religious (Salat) Behavior and Suicidality among Youth in Pakistan

The manuscript studied religious (Salat) behavior and its link with the probability of suicide among Muslim youth in Pakistan. After careful analysis of scientific literature, it was hypothesized that “young adults who are regular in the practice of religious behavior (Salat) would have a lower score on the measures of suicidal behavior as compared to those who are irregular and rarely/occasionally practice religious behavior (Salat)". A sample of 418 young adults was gathered from different universities. There were n = 210 men and n = 208 women, and they were further divided into three groups based on how they performed Salat. Group 1 consisted of those who reported regular practice of Salat; Group 2 reported irregularly performing Salat; and Group 3 reported that they rarely/occasionally performed Salat. The participants’ ages ranged from 19 to 25 years old. The findings show that young adults (i.e. regularly practice religious behavior (salat) scored significantly low on variables of suicidal behavior as compared to those young adults who were irregularly or occasionally practice religious behavior (Salat) [F(2,415) = 11.632, p<. 05]. It was concluded that Muslim religious behavior (Salat) is beneficial, especially for those who are facing challenges of suicidal behavior. This research has provided a basis for future research.
Effect of Solute on Interfacial Properties and Micelle Structure of Dodecylbenzenesulfonate (DBS): Experimental and Molecular Dynamics Studies

A combined experimental and molecular dynamic simulation approach was used to examine the structure and interfacial properties of solute-saturated micelles. The properties of dodecylbenzenesulfonate (DBS) micelles were examined in dodecane and benzene hydrocarbon systems. Pyrene fluorescence was used to determine the aggregation number of surfactant monomers in the micelle systems. Molecular dynamic (MD) simulations using energy minimization applying the CHARMm force field with the TIP3P model for water. Comparison of the DBS/benzene and DBS/Dodecane micelles equilibrium structures via radial distribution function (RDF) and probability distribution function (PDF) analysis indicates that the area per head group for the DBS/Benzene micelle interface is significantly larger than that of the DBS/Dodecane at the interface. It was also determined that benzene molecules can move freely within the micelle while dodecane is strictly confined in the core of the micelle. The increased interfacial area per monomer caused by the insertion of benzene also reduces the effectiveness of the surfactant, which has implications for use in various environmental applications. However, the DBS/benzene micelle can solubilize many more hydrocarbon molecules in one micelle with less surfactant monomer (i.e., lower aggregation number) per micelle due to the increased available packing positions within the micelle. This, in turn, increases the efficiency of the surfactant in real-world applications which is consistent with previous laboratory results. Understanding the differing solubilization characteristics of surfactants against various classes of hydrocarbons in single solute systems is a necessary step to beginning to understand their solubilization properties in the mixed waste systems prevalent in most surfactant enhanced remediation (SEAR) strategies.
Environmental attitudes and connections to landscapes of undergraduate regional field course students

A fundamental goal of geoscience education is to ensure that all people have a basic understanding of the natural processes that shape the earth (Locke, Libarkin, & Chang, 2012). Field studies courses are offered at many colleges and universities in the United States and give students access to hands-on learning and outdoor experiences. In-depth outdoor experiences can influence environmental attitudes (Okada, Okamura, & Zushi, 2013). Other research has indicated that outdoor field experiences enhance student enthusiasm, motivation, and learning (Boyle et al., 2007; Hope, 2009). This study examined student connections with landscapes, and emotional responses of students to the field course experience. Surveys were completed by students participating in one of four earth science field courses. The data was analyzed to determine whether students developed personal connections to the locations of the field course, and whether this experience influenced their environmental attitudes. The researcher found that the environmental attitudes of the students surveyed did not change significantly (p<.05). Many students reported no change in their environmental attitudes, but a number of students did indicate a deepening of appreciation for the natural world. Additionally, the study found that many students did develop personal connections to the location(s) of their field courses. The personal connections developed by students ranged from spiritual connections, intellectual connections, and personal desires to protect the places where they went on the field course.
Relative Impacts of Ice Storms on Loblolly Pine Plantations in Central Arkansas

Catastrophic ice storms can inflict widespread damage to forests in the Southeastern United States. Two severe ice storms struck Arkansas in December 2000, resulting in heavy losses to loblolly pine (Pinus taeda L.) plantations. We assessed the type and magnitude of damage in four loblolly pine plantation conditions: unthinned 11- to 12-year-old stands, once-thinned 18- to 19-year-old stands, twice-thinned 24- to 25-year-old stands, and at least twice- thinned > 28-year-old stands. Each condition was replicated three times on similar sites. Patterns in tree damage extent and type were apparent between plantations of different ages and thinning histories. The oldest plantations had the greatest proportion of undamaged survivors, while the youngest stands received the highest injury. Young loblolly pines suffered from bent stems more often than trees in older plantations. Loblolly pines in the oldest plantations were virtually immune to stem damage yet experienced frequent crown and branch loss. Intermediate-aged plantations had somewhat more stem breakage and uprooting than either younger or older pine plantations. Differences in the degree and type of damage were closely related to tree size and stand attributes. Logistic regression models were also developed to predict severe damage probability from stem diameter and tree density.
Mitochondrial PE potentiates respiratory enzymes to amplify skeletal muscle aerobic capacity

Mitochondrial membrane lipids adapt to exercise or disuse, underscoring an essential role for PE in energy transduction. Exercise capacity is a strong predictor of all-cause mortality. Skeletal muscle mitochondrial respiratory capacity, its biggest contributor, adapts robustly to changes in energy demands induced by contractile activity. While transcriptional regulation of mitochondrial enzymes has been extensively studied, there is limited information on how mitochondrial membrane lipids are regulated. Here, we show that exercise training or muscle disuse alters mitochondrial membrane phospholipids including phosphatidylethanolamine (PE). Addition of PE promoted, whereas removal of PE diminished, mitochondrial respiratory capacity. Unexpectedly, skeletal muscle–specific inhibition of mitochondria-autonomous synthesis of PE caused respiratory failure because of metabolic insults in the diaphragm muscle. While mitochondrial PE deficiency coincided with increased oxidative stress, neutralization of the latter did not rescue lethality. These findings highlight the previously underappreciated role of mitochondrial membrane phospholipids in dynamically controlling skeletal muscle energetics and function.
The Prevalence of Pulmonary Hypertension in Beta-Thalassemia Patients in Hormozgan Province: A Cross-sectional Study

Background: Pulmonary hypertension (PH) is associated with an increased risk of cardiac failure among asymptomatic patients with beta-thalassemia. This study aimed to determine the prevalence of PH and associated risk factors in patients with beta-thalassemia major (TM) and beta-thalassemia intermedia (TI) in Hormozgan province, Iran. Materials and Methods: Eighty-nine patients, including 65 TM and 24 TI, were enrolled in this cross-sectional study. The data regarding the gender, age, history of splenectomy, and type of chelating therapy were collected, and then hematocrit, hemoglobin (Hb), and serum ferritin levels were determined. Doppler echocardiography was performed for patients, and tricuspid regurgitation jet velocity (TRV)≥2.5 m/s was used to screen PH. Eventually, the data were analyzed using SPSS. Results: The prevalence of TRV≥2.5 m/s was 21.3% in all patients, indicating that it was not significantly different between patients with TM (21.8%) and TI (20.8%). There was a significant association between the prevalence of PH and the male gender. Based on the results, TRV≥2.5 m/s was observed in both children and adults. No significant association was detected between Hb, serum ferritin levels, and splenectomy with PH prevalence. Conclusion: The findings revealed that PH is common in both children and adult patients with TM and TI in our population and should be considered to choose the optimal treatment of patients with TM and TI.
SELECTION OF SINGLE PLANTS OF SWEET POTATO (IPOMOEA BATATAS L.) RESULTS OF OPEN-CROSS IN FEMALE PARENT BETA-2 FOR ORANGE-FLESHED SWEET POTATO AND HIGH PRODUCTION

Sweet potato (Ipomoea batatas L.) is one of the alternative commodities in food diversification. Apart from being a source of carbohydrates, orange-fleshed sweet potatoes contain lots of beta-carotene (pro-vitamin A) and antioxidants that contribute greatly to health. Efforts to improve the quality of orange sweet potatoes in quantity and quality are still very much needed, one of which is by crossing. The study aimed to obtain high-yielding orange-fleshed sweet potato lines from free crosses between female parent Beta-2 and male parent local sweet potato Lampung (LPG-01, LPG-03, LPG-06, LPG-11), Cilembu, Ayamurasaki. The method used in this selection is a single planting selection method by looking at the morphological characters of each line. Single planting selection is the initial selection after successful crossing. The results showed that of the 79 lines that were crossed by a female parent of Beta-2, there were 19 lines with orange flesh and high yields, namely Beta2 OP1, Beta2 OP3, Beta2 OP4, Beta2 OP6, Beta2 OP8, Beta2 OP19, Beta2 OP25, Beta2 OP30, Beta2 OP33, Beta2 OP34, Beta2 OP36, Beta2 OP38, Beta2 OP42, Beta2 OP43, Beta2 OP54, Beta2 OP58, Beta2 OP63, Beta2 OP73, Beta2 OP77
Does Pornography Presuppose Rape Myths?

Rae Langton and Caroline West argue that pornography silences women by presupposing misogynistic attitudes, such as that women enjoy being raped. More precisely, they claim that a somewhat infamous pictorial, ‘Dirty Pool’, makes such presuppositions, and that it is typical in this respect. I argue for four claims. (1) There are empirical reasons to doubt that women are silenced in the way that Langton and West claim they are. (2) There is no evidence that very much pornography makes the sorts of presuppositions that Langton and West's explanation of silencing requires it to make. (3) Even ‘Dirty Pool’, for all its other problems, does not make such presuppositions. (4) Langton and West misread ‘Dirty Pool’ because they do not take proper account of the fact that pornography often traffics in sexual fantasy. The broader lesson is that we need to read pornography more sensitively if we are to understand its capacity to shape socio‐sexual norms (for good or for ill).
Global knowledge-power asymmetries and student mental health in sub-Saharan Africa

In the past decade concern about the mental health of university students has been growing worldwide. Yet epidemiological data and intervention research on student mental health comes predominantly from high income western countries in the Global North, with a relative scarcity of studies from sub-Saharan Africa and other countries in the Global South. While universities in the Global North and Global South face similar challenges to provide accessible, acceptable, and effective mental health services to students, there are also important historical, cultural, economic, and political issues that make it necessary for context-sensitive research which is responsive to the needs of students in the Global South. Using South Africa (SA) as a case study, this commentary aims to explore the relevance and appropriateness of uncritically importing knowledge and “evidence-based” strategies to student mental health challenges from the Global North into sub-Saharan Africa.
Contemporary review on pediatric hypertrophic cardiomyopathy: insights into detection and management

Hypertrophic cardiomyopathy is the most common genetic cardiac disorder and is defined by the presence of left ventricular (LV) hypertrophy in the absence of a condition capable of producing such a magnitude of hypertrophy. Over the past decade, guidelines on the screening, diagnostic, and management protocols of pediatric primary (i.e., sarcomeric) HCM have undergone significant revisions. Important revisions include changes to the appropriate screening age, the role of cardiac MRI (CMR) in HCM diagnosis, and the introduction of individualized pediatric SCD risk assessment models like HCM Risk-kids and PRIMaCY. This review explores open uncertainties in pediatric HCM that merit further attention, such as the divergent American and European recommendations on CMR use in HCM screening and diagnosis, the need for incorporating key genetic and imaging parameters into HCM-Risk Kids and PRIMaCY, the best method of quantifying myocardial fibrosis and its prognostic utility in SCD prediction for pediatric HCM, devising appropriate genotype- and phenotype-based exercise recommendations, and use of heart failure medications that can reverse cardiac remodeling in pediatric HCM.