Miracle-dz/UniFAR-FTUs huggingface dataset:
Perancangan Fasilitas Kerja pada Operator Pemasangan Accesories di CV. X untuk Mengurangi Risiko Musculoskeletal Disorders (MSDs)

Abstract. CV. X is a company engaged in the convection of women's bags and mini backpacks. CV. X uses the make to order process. In the process of making a mini backpack, the activities are carried out in a sitting position according to the standard, namely the sewing process, while for the process of the pattern, the cutting process, and the process of installing the accessories are done in a sitting position on the floor without a base. Based on the results of interviews with operators, it was found that the most complaints with the working conditions of the neck bowed, back bent, sat barefooted with legs crossed occurred in the operator mounting accessories. The method used is the OWAS method and the Nordic Body Map Questionnaire. Based on the results of interviews and the Nordic Body Map questionnaire, complaints were felt that consisted of neck, lower back and lower legs, knees, buttocks, and ankles. The following conditions cause muscle injury, musculoskeletal disorders. The results of the determination of work risk using the Ovako Working Analysis System (OWAS) method obtained all work elements in the process of installing accessories with the second level category, namely the process of gluing spots, cutting relief materials, linking relief and hurdles, linking spots, uniting all elements, and installing accessories. Abstrak. CV. X merupakan perusahaan yang bergerak dibidang konveksi tas wanita dan mini backpack. CV. X menggunakan proses make to order. Pada proses pembuatan tas mini backpack yang aktivitasnya dikerjakan dengan posisi duduk sesuai standar yaitu proses penjahitan, sedangkan untuk proses pola, proses potong, dan proses pemasangan accesories dikerjakan dengan posisi duduk dilantai tanpa alas dilakukan secara berulang-ulang dan dalam jangka waktu yang lama. Berdasarkan hasil wawancara dengan operator didapatkan bahwa keluhan terbanyak dengan kondisi kerja leher menunduk, punggung membungkuk, duduk tanpa alas dengan kaki menyilang terjadi pada operator pemasangan accesories. Metode yang digunakan yaitu metode OWAS dan Kuisioner Nordic Body Map. Berdasarkan hasil dari wawancara dan kuisioner Nordic Body Map diperoleh keluhan yang dirasakan terdiri dari bagian leher, punggung atas dan bawah, lutut, bokong/paha, dan pergelangan kaki. Hasil dari penentuan risiko kerja menggunakan metode Ovako Working Analysis System (OWAS) didapat seluruh elemen kerja pada proses pemasangan accesories dengan kategori level dua yaitu proses merekatkan bintik, menggunting bahan lega, mengaitkan lega dan gawang, mengaitkan bintik, menyatukan semua elemen, dan pemasangan accesories.
The Role of Chromogenic Replica System for Isolation & Identification of Uropathogens in the Era of Molecular Diagnostics

Multidrug resistance in uropathogens is a serious problem in a health care set up. To deal with that, rapid identification of the etiological agent from clinical urine sample is utmost important. Use of replica disc for presumptive identification of uropathogens is an easy to perform, cost effective and rapid method, which can be, adopted in the microbiology laboratories as a primary screening method.
A Financial Profile of Firms Awarded the Highest Technical Ratings by Value Line in a Period of High Economic Growth

This study examines the financial characteristics of the group of firms that have been identified by Value Line as having the highest technical ratings in their database during the four years preceding the 2020 occurrence and resulting economic downturn of the coronavirus-19 pandemic. That period was characterized by a high level of economic growth, low unemployment, and record-high equity markets. Those highest-ranking firms are compared with firms chosen at random, but from the same industries, to determine whether the firms with the high technical ratings in such an economic environment have a unique risk-return profile, and by implication, a heretofore unknown relationship between technical and fundamental analysis. As in previous studies of this type, multiple discriminant analysis is used to identify the characteristics that most highly separate the two groups of firms, and canonical correlation ranks the discriminant variables.
THE IMPACT OF THE STRENGTH OF LEGAL RIGHTS ON CASH HOLDINGS: EVIDENCE FROM AN EMERGING MARKET

This paper investigates the impact of the strength of legal rights on cash holdings. An increase in legal rights can facilitate corporate lending and therefore reducing companies’ need of holding cash. Using a sample consisting of Vietnamese listed companies from 2012 to 2019, we show that strong legal rights can lead to a decrease in the level of corporate cash holdings. This result is robust when we use alternative measures of corporate cash holdings or when we use different econometric models to deal with endogeneity problems. Moreover, our results indicate that the negative relationship between legal rights and corporate cash holdings exists only when firms have positive retained earnings. One of the explanations may be because only firms with positive retained earnings are able to access the source of bank financing and therefore can reduce the need of holding cash. Given that a company can have a high opportunity costs when holding a high level of cash, our paper suggests that regulators should have policies that increase the legal rights so that companies can reduce the cash holdings.
The Role of General Practitioners in Suicide Prevention-What you Said and Did then Actually Saved my Life

Background: General Practitioners (GP) have an important role in the prevention of suicidal behavior. The purpose of this study was to explore their views and experiences of identifying and assessing suicidal ideation. Methods: Ten GPs were recruited through convenience sampling, based on accessibility, interest and willingness to participate. In-depth interviews were carried out and results transcribed ver-batim. Aspects of experiences with suicidal patients emerged through the thematic analyses process. Results: The GPs described the varied clinical picture when patients presented in their office. How they identified depressive symptoms apart from originally somatic complaints, formed a trusting relationship and addressed suicide ideation. They described customized interventions as well as obstacles and factors that facilitated communication: time, own personal traits, pa-tient’s disclosure and organizational barriers. Conclusions: The levels of the suicidal process among patients in general practice vary greatly. GPs adjust their appraisals to profundity understand and intervene in order to prevent a crisis to escalate into subsequent suicidal behavior.
Prevalence of myopia among primary school students in mainland China: a Meta-analysis

Centre for Health Management and Policy, Shandong University, Jinan 250012, Shandong Province, China Key Lab for Health Economics and Policy Research, Ministry of Health, Jinan 250012, Shandong Province, China Affiliated Eye Hospital of Shandong University of Traditional Chinese Medicine, Jinan 250014, Shandong Province, China Correspondence to: Shun Ping Li. Centre for Health Management and Policy, Shandong University, Jinan 250012, Shandong Province, China; Key Lab for Health Economics and Policy Research, Ministry of Health, Jinan 250012, Shandong Province, China. lishunping@ sdu. edu. cn Received: 2015-03-10摇 摇 Accepted: 2016-04-19
The effect of beetroot juice on exercise performance in normoxia and moderate hypoxia

ii Preface . iii Table of contents . iv List of tables . vi List of figures . vii List of abbreviations . viii Acknowledgements . ix 1. Introduction . 1 1.1 Overview . 1 1.2 Aerobic exercise . 1 1.2.1 Adaptations to endurance exercise . 2 1.2.3 Determinants of performance . 3 1.2.4 Limitations to aerobic capacity and performance . 5 1.2.5 Aerobic exercise in hypoxia . 5 1.2. 6 Effects of altitude training . 6 1.3 Exercise and nitrate . 7 1.3. 1 Nitric oxide pathways . 9 1.3. 2 Sex differences in response to nitrate supplementation . 11 1.3. 3 Effect of beetroot juice on exercise . 11 1.3. 4 Nitrate supplementation and normoxic exercise performance . 13 1.3. 5 Beetroot juice and hypoxic performance studies . 14 1.3. 6 Nitric oxide in hypoxia . 14 1.4 Summary and potential significance . 16 2. Effect of beetroot juice on exercise performance in normoxia and moderate hypoxia . 17 2.1 Introduction . 17 2.2 Purpose, objectives and hypotheses . 18 2.3 Methods . 19 2.3. 1 Participant information . 19 2.3. 2 Experimental design . 19 2.3. 3 Statistical analysis . 25 2.4 Results . 26 2.4. 1 Subject characteristics . 26 2.4. 2 Hypoxic and normoxic exposures . 27 2.4. 3 Resting blood pressure and FENO . 27 2.4. 4 Steady-­‐state cycling . 29 2.4. 5 10-­‐km time trial . 29 2.5 Discussion . 33 2.5. 1 Layout of discussion . 33 2.5. 2 Pre-­‐ and post-­‐supplementation variables . 33 2.5. 3 Blood pressure . 34
Downscaling runup

Runup parameterization and beach vulnerability assessment on a barrier island: a downscaling approach G. Medellín, J. A. Brinkkemper, A. Torres-Freyermuth, C. M. Appendini, E. T. Mendoza, and P. Salles Cátedras-CONACyT, Consejo Nacional de Ciencia y Tecnología, México, D. F. , Mexico Laboratorio de Ingeniería y Procesos Costeros, Instituto de Ingeniería, Universidad Nacional Autónoma de México, Sisal, Yucatán, Mexico Department of Physical Geography, Faculty of Geosciences, Utrecht University, Utrecht, the Netherlands
Depression and Anxiety among Sexual Minorities in Iceland

Depressive symptoms and anxiety symptoms are significantly higher among nonheterosexual individuals compared to heterosexual individuals. Scholars have suggested that this is due to increased stressful social environment that non-heterosexual individuals experience. The current study aimed to explore the difference in depressive and anxiety symptoms between non-heterosexual adolescents and heterosexual adolescents in Iceland. The role of parental social support, peer social support and the experience of sexual abuse were examined as contributors to a higher level of depressive symptoms and anxiety symptoms among non-heterosexual individuals. Results indicated that the non-heterosexual adolescents showed significantly more depressive symptoms and anxiety symptoms compared to their heterosexual peers. Non-heterosexual adolescents were more likely to have experienced sexual abuse and they also experienced lower parental social support compared to their heterosexual peers. Regression analysis showed that higher levels of depressive symptoms and anxiety symptoms among the non-heterosexual sample was only significant when there was no history of sexual abuse. Results are discussed from a theoretical perspective. Longitudinal studies on the development of different sexual attraction patterns are suggested for future research.
GENERATIONAL DIFFERENCES IN MORAL PROCESSING STYLES

Moral decision-making is a core feature of human life. We explored whether generational differences exist in the preference for two types of moral processing styles (the ways in which we integrate moral information and decide to take action): moral reasoning and moral intuition. We analyzed preferences for moral processing styles by using a modified version of the Rational-Experiental Inventory (REI) scale, which was broken down into the Faith in Moral Intuition and Need For Moral Cognition subscales. Preferences for moral intuition and moral reasoning were measured by averaging Faith in Moral Intuition scores and Need for Moral Cognition scores from 120 Generation Z (born after 1996) and 50 Generation X (born between 1965 1980) participants. A mediation analysis was also conducted to see if social media usage would explain the expected differences between generations. Gen Z participants scored lower than Gen X participants on Need For Moral Cognition, but no differences emerged on Faith in Moral Intuition. However, the mean difference between Faith in Moral Intuition and Need For Moral Cognition was much larger for Gen X than Gen Z. Social media usage did not mediate the relationship between generation and moral processing styles. It appears that there are generational preferences for moral processing styles, and that moral reasoning is less valued by this younger generation. The reason that these generational differences emerged must be examined in future research.
AVT and IT regulate ion transport across the opercular 1 epithelium of killifish ( Fundulus heteroclitus ) and gilthead 2 sea bream ( Sparus aurata ) 3 4 5

35 The regulatory role of arginine vasotocin (AVT) and isotocin (IT) in Cl secretion was 36 investigated with the short-circuit current (Isc) technique in opercular epithelia of 37 killifish (Fundulus heteroclitus) and gilthead sea bream (Sparus aurata). Sea bream 38 operculum showed ~4 fold lower number of Na/K-ATPase immunoreactive cells and 39 ~12 fold lower secretory current than the killifish. In sea bream opercular membranes, 40 basolateral addition of AVT (10 M) significantly stimulated Cl secretion, while IT 41 (10 M) was without effect. In killifish, IT produced an immediate dose-dependent 42 stimulation of Cl secretion with significant effect at doses ≥10 M and stimulation 43 maxima (∆Isc ~25 μA.cm) at 10 M. Basolateral addition of bumetanide (200 μM) 44 abolished >75% of the effect of IT on Cl secretion. In turn, AVT had a dual effect on 45 killifish opercular Isc: an immediate response (~3 min) with Isc reduction in an 46 inverted bell-shaped dose-response manner with higher current decrease (-22 μA.cm 47 ) at 10 M AVT, and a sustained dose-dependent stimulation of Cl secretion (stable 48 up to 1 h), with a threshold significant effect at 10 M and maximal stimulation (~20 49 μA.cm) at 10 M. Both effects of AVT appear receptor-type-specific. The V150 receptor antagonist SR 49059 abolished Isc reduction in response to AVT; while the 51 specific V2-receptor antagonist (Tolvaptan, 1 μM) abolished the stimulatory action of 52 AVT on Cl secretion. According to these results, we propose a modulatory role for 53 AVT and IT in Cl (NaCl) secretion across the opercular epithelium of marine teleost. 54 55
Vaccines against Coronaviruses of Veterinary Importance Impfstoffe gegen veterinärmedizinisch relevante Coronaviren

CC BY-NC-ND 4.0 Die COVID-19-Pandemie hat die Entwicklung von Impfstoffen gegen SARSCoV-2 in beispielloser Weise vorangetrieben. Rund 170 Impfstoffprojekte sind von der WHO gelistet und bei 29 dieser Projekte wurde bereits mit klinischen Studien begonnen. Während Wissenschaftler auf der ganzen Welt bestrebt sind, einen wirksamen Impfstoff zu entwickeln, kann es hilfreich sein, einen Blick in den Hinterhof der Coronavirus-Forschung zu riskieren. In der Veterinärmedizin gibt es eine lange Geschichte der Impfstoffentwicklung gegen Coronaviren. Der vorliegende Übersichtsartikel will Impfansätze gegen Coronaviren bei Hühnern, Schweinen, Rindern und Katzen vorstellen. Stammvariationen der Viren, die Induktion einer wirksamen Schleimhautimmunität und die Vermeidung von Immunopathologie sind nur einige der vielfältigen Herausforderungen, denen man sich auf dem Weg zum wirksamen Coronavirus-Impfstoff stellen muss. Obwohl es sich immer wieder als schwierig erwiesen hat, eine sterile Immunität zu erreichen, haben sich in der Veterinärmedizin abgeschwächte Lebendimpfstoffe bewährt. Sie tragen dazu bei, die klinischen Symptome zu verringern und wirtschaftliche Verluste zu minimieren. Für SARS-CoV-2 werden möglicherweise Ansätze der reversen Vakzinologie die vielfältigen Herausforderungen überwinden und zu einer schnellen Entwicklung eines wirksamen Impfstoffes gegen das Pandemievirus führen.
ADMISSION HYPERGLYCEMIA IN CRITICALLY ILL PATIENTS WITH SEPSIS; HIGH IL6 AND ITS RELATION WITH OUTCOME

Background: Hyperglycemia has long been recognized as a common occurrence in critically ill patient, even without history of diabetes mellitus (D.M). Although there are few studies investigating the prevalence of stress hyperglycemia, one study reported that 38% of patients admitted to general hospitals had hyperglycemia episodes, 16% of which had no previous history of D.M. Objective: To investigate the role of high IL6 in patients with sepsis admitted to medical I.C. U with acute hyperglycemia and its relation to 30 days outcome. Patients and Methods: This study was conducted on 100 adult septic patients who were admitted to medical I.C. U at Al-Hussein University Hospital, the study was carried in the period between January 2018 and June 2019. 80 patients with evidence of hyperglycemia and 20 patients with euglycemic state. Results: non-significant difference was found according to mean values of Na+, K+, creat, TLC, HB%, PLT, ALT, AST. On the other hand, the hyperglycemic group showed a significant increase regarding mean value of HbA1c compared to control group. The comparative study between the 2 groups revealed a significant increase of mean value of CRP in the hyperglycemic group compared to the control group. As regards the vital signs, the hyperglycemic group showed a significant increase in mean values of systolic blood pressure, diastolic blood pressure, MAP & HR compared to the control group. While there was no significant difference between the 2 groups regarding temperature and RR. This study showed statistically significant decrease in mean values of GCS in hyperglycemic group compared to control group, while APACHE II and qSOFA showed a significant increase in hyperglycemic group compared to control group. The mean values of ABG parameters revealed no statistically significant difference between the 2 groups. On the other hand, mean values of RBS and IL6 showed a statistically significant increase in hyperglycemic group compared to control group. The comparative study between the 2 groups showed a significant increase in mean values of hyperglycemic group compared to control group according to duration of ICU stay (days), Insulin therapy, AKI and Outcome and non-significant difference according to ILD, CLD, CKD, stroke, pneumonia, IHD, COPD & HF. Conclusion: Stress hyperglycemia with high IL6 is strongly associated with adverse outcomes in patients with sepsis who were admitted to the medical ICU. Sepsis patients with hyperglycemia showed increased incidence of mortality and AKI.
Microsoft Word-10655642-file00

Pavle M. Joksovic, Won Joo Choe, Michael T. Nelson, Peihan Orestes, Barbara C. Brimelow and Slobodan M. Todorovic Departments of Anesthesiology (PMJ, WJC, PO, MTN, BCB, SMT), Neuroscience (SMT) and Neuroscience Graduate Program (PO, SMT) University of Virginia Health System, Charlottesville, VA; (PMJ present address) Department of Psychiatry, Yale University, 300 George St. Suite 901, New Haven CT 06511 (WJC present address) Department of Anesthesiology, InJe University, Ilsan Paik Hospital & College of Medicine, Goyang-city 411-706, Gyunggi-do, South Korea Molecular Pharmacology Fast Forward. Published on October 21, 2009 as doi:10.1124/mol.109. 059931
Association between the prion protein gene polymorphisms and incidence of fatal familial insomnia: a casecontrol study in a Chinese population

This study aimed to explore the association between the prion protein gene (PRNP) polymorphisms and incidence of fatal familial insomnia (FFI) in a Chinese population. Twenty FFI patients were chosen as the case group and forty healthy individuals as the control group. PRNP gene polymorphism sites were screened out, and M129V and E219K were identified as the polymorphic sites. Peripheral blood was extracted from all subjects for PRNP detection and genotyping using polymerase chain reaction restriction fragment length polymorphism. Epidemiological case investigation was conducted in the FFI patients to collect related information. Multivariate logistic regression analysis was employed to screen independent risk factors of FFI and SHEsis online software was used to analyze the haplotypes of M129V and E219K sites of PRNP. Family history, body weight and sleep duration were significantly different in the case group. The M/M, M/V genotypes and M allele at the M129V of PRNP gene could increase the risks of FFI, indicating that carrying 129M/M and 129M/V genotypes were more likely to suffer from FFI than those with 129V/V genotype. The M/M genotype in M129V was significantly correlated with the natural history, disease progression, neurological and pathological changes, loss of weight, electroencephalogram abnormality and sleep time. Multivariate logistic regression analysis indicated that the M/M, M/V genotypes at M129V of PRNP gene, FFI family history, body weight loss and sleep duration < 3 h were all risk factors of FFI. Additionally, VE haplotype might be a potential protective haplotype for FFI (OR = 0.293, 95% CI = 0.093~0.919). These results collectively indicated that the PRNP M129V polymorphisms may be associated with the incidence of FFI.
Association of gestational diabetes mellitus with preeclampsia: a retrospective cohort study

Objective: To explore the impact of gestational diabetes mellitus (GDM) on preeclampsia. Methods: Singleton pregnant women who registered in our hospital between January 2010 and January 2020 were enrolled in this retrospective cohort study. GDM is diagnosed according to the criteria of the International Association of Diabetes and Pregnancy Study Groups Consensus. Univariate and multivariate logistic regression analyses were conducted to estimate the relative risk between GDM and preeclampsia. Results: Among the 800 singleton pregnancy women analyzed, 66 (8.25%) was diagnosed with GDM. We found that women with GDM had a higher risk of developing preeclampsia than women with non-GDM (12.12% vs. 4.09%, P<0.05). Multivariate analysis showed that GDM (odds ratio [OR] 2.95, 95% confidence interval [CI] 1.28-6.83), pre-pregnancy BMI ≥25 (OR 3.15, CI 1.377.28) and dyslipidemia (OR 2.53, CI 1.01-6.33) were significantly associated with preeclampsia. Conclusion: GDM, pre-pregnancy BMI ≥25 and dyslipidemia are significantly associated with preeclampsia.
Tailoring Alginate/Chitosan Microparticles Loaded with Chemical and Biological Agents for Agricultural Application and Production of Value-Added Foods

This work reviews the recent development of biopolymer-based delivery systems for agricultural application. Encapsulation into biopolymer microparticles ensures the protection and targeted delivery of active agents while offering controlled release with higher efficiency and environmental safety for ecological and sustainable plant production. Encapsulation of biological agents provides protection and increases its survivability while providing an environment safe for growth. The application of microparticles loaded with chemical and biological agents presents an innovative way to stimulate plant metabolites synthesis. This enhances plants’ defense against pests and pathogens and results in the production of higher quality food (i.e., higher plant metabolites share). Ionic gelation was presented as a sustainable method in developing biopolymeric microparticles based on the next-generation biopolymers alginate and chitosan. Furthermore, this review highlights the advantages and disadvantages of advanced formulations against conventional ones. The significance of plant metabolites stimulation and their importance in functional food production is also pointed out. This review offers guidelines in developing biopolymeric microparticles loaded with chemical and biological agents and guidelines for the application in plant production, underlining its effect on the plant metabolites synthesis.