Miracle-dz/UniFAR-FTUs huggingface dataset:
Principles of Neurology, 5th Ed.

throughout. The chapter, “Periodic Paralyses and Related Myotonic Diseases,” is, like many others in this book, succinct, well written, and a pleasure to read. It is a paradox that while chromosome location and defective gene are already established for hyperkalemic periodic paralysis, paramyotonia congenita, and myotonia congenita, they have not been determined in the case of the more common disorder, hypokalemic periodic paralysis. The chapter, “Bell’s Palsy and Idiopathic Cranial Neuritis,” overstates the frequency with which Bell’s palsy is found in association with other, more subtle manifestations of cranial neuritis. Robert G. Miller’s discussion of the “Chronic Fatigue Syndrome” is intelligent and fair, emphasizing the importance of normal diagnostic studies, the frequency of depression, and a coherent therapeutic approach: “I provide substantial reassurance about the relatively benign nature of the diagnosis and the strong tendency towards spontaneous improvement in the majority of patients. ” This is a volume that you will want to use as more than a reference source. The brief individual subject chapters can comfortably, profitably, and pleasantly be read in full.
Robust Solutions to Uncertain Multiobjective Programs

Decision making in the presence of uncertainty and multiple conflicting objectives is a real-life issue, especially in the fields of engineering, public policy making, business management, and many others. The conflicting goals may originate from the variety of ways to assess a system’s performance such as cost, safety, and affordability, while uncertainty may result from inaccurate or unknown data, limited knowledge, or future changes in the environment. To address optimization problems that incorporate these two aspects, we focus on the integration of robust and multiobjective optimization. Although the uncertainty may present itself in many different ways due to a diversity of sources, we address the situation of objective-wise uncertainty only in the coefficients of the objective functions, which is drawn from a finite set of scenarios. Among the numerous concepts of robust solutions that have been proposed and developed, we concentrate on a strict concept referred to as highly robust efficiency in which a feasible solution is highly robust efficient provided that it is efficient with respect to every realization of the uncertain data. The main focus of our study is uncertain multiobjective linear programs (UMOLPs), however, nonlinear problems are discussed as well. In the course of our study, we develop properties of the highly robust efficient set, provide its characterization using the cone of improving directions associated with
HexaConv

The effectiveness of Convolutional Neural Networks stems in large part from their ability to exploit the translation invariance that is inherent in many learning problems. Recently, it was shown that CNNs can exploit other invariances, such as rotation invariance, by using group convolutions instead of planar convolutions. However, for reasons of performance and ease of implementation, it has been necessary to limit the group convolution to transformations that can be applied to the filters without interpolation. Thus, for images with square pixels, only integer translations, rotations by multiples of 90 degrees, and reflections are admissible. Whereas the square tiling provides a 4-fold rotational symmetry, a hexagonal tiling of the plane has a 6-fold rotational symmetry. In this paper we show how one can efficiently implement planar convolution and group convolution over hexagonal lattices, by re-using existing highly optimized convolution routines. We find that, due to the reduced anisotropy of hexagonal filters, planar HexaConv provides better accuracy than planar convolution with square filters, given a fixed parameter budget. Furthermore, we find that the increased degree of symmetry of the hexagonal grid increases the effectiveness of group convolutions, by allowing for more parameter sharing. We show that our method significantly outperforms conventional CNNs on the AID aerial scene classification dataset, even outperforming ImageNet pre-trained models.
6-(3,5-Dimethylbenzyl)-5-ethyl-1-[(2-phenoxyethoxy)methyl]-1,2,3,4-tetrahydropyrimidine-2,4-dione

The six-membered ring of the uracil part of the title compound, C24H28N2O4, is nearly planar (r.m.s. deviation = 0.013 Å); the aromatic ring of the 3,5-dimethylbenzyl substitutent is aligned at 85.4 (1)° with respect to this mean plane. The phenyl ring of the substituent at the 1-position takes up two orientations in a 1:1 ratio. In the crystal, two molecules are liked by a pair of N—H⋯O hydrogen bonds, generating a centrosymmetric hydrogen-bonded dimer.
tRuEcasIng

Truecasing is the process of restoring case information to badly-cased or non-cased text. This paper explores truecas-ing issues and proposes a statistical, language modeling based truecaser which achieves an accuracy of (cid:24) 98 % on news articles. Task based evaluation shows a 26% F-measure improvement in named entity recognition when using truecasing. In the context of automatic content extraction, mention detection on automatic speech recognition text is also improved by a factor of 8. Truecasing also enhances machine translation output legibility and yields a BLEU score improvement of 80 : 2% . This paper argues for the use of truecasing as a valuable component in text processing applications.
Diabetic retinopathy; knowledge, attitudes and practice among general practitioners in provincial hospitals in Kenya

Background: Diabetes is increasingly becoming a significant problem in Kenya with more than three million people affected. Diabetic retinopathy, a complication of diabetes is among the leading causes of avoidable and preventable blindness. There are no data on awareness of diabetic retinopathy among general practitioners (GPs) in Kenya. The GPs are the primary health care providers for most diabetic patients. As such they are well placed to assess ahd refer diabetic patients to the eye specialists. This study aimed at evaluating the awareness of diabetesrelated eye disease among GPs working at provincial hospitals in Kenya. Design: A cross-sectional study Objective: To assess and determine the knowledge, attitudes and practices of general practitioners working at provincial hospitals in Kenya toward diabetic retinopathy. Methodology: The study was carried out at seven provincial general hospitals in Kenya. Participants comprised of general practitioners working at these hospitals. The GPs were given a self administered questionnaire following which the data collected was coded, entered and managed in a pre-designed Microsoft Access database. Data analysis was carried out using SPSS version 17.0. Results were presented in tables, graphs and pie charts. Results: Ninety one GPs were interviewed over a period of two months in the seven PGH's. The male to female ratio was 1: 1 and mean age was 27.8years (SD 4). The level of knowledge regarding diabetes and its complications was good among the study GPs. All GPs (100%) indicated that the eyes and visual function can be impaired in DM. There were gaps noted regarding the factors influencing the presence, severity and complications of DR. Only 46.2% and 33% were aware ofrenal disease and pregnancy respectively as being factors that can affect presence and severity of DR. Among the GPs in the study 65.9% and 52.7% were not aware of vitreous hemorrhage and retinal detachment respectively as being complications of DR. The practice patterns of GPs in regard to DR were generally poor with 60.5% never examining vision or only doing so when the patient complained of visual symptoms. Among these GPs 63.7% never examine the retina of their diabetic patient while 38.5% only refer DM patients to the eye specialist when they have a complaint. Conclusions: This study establishes gaps in the knowledge on diabetic retinopathy among general practitioners working at provincial hospitals in Kenya. This included lack awareness of sight threatening complications of diabetic retinopathy such as retinal detachment and vitreous hemorrhage. It also established that the GPs had good attitude toward DR though this did not translate to good practice patterns.
Paid Living-Unrelated Renal Transplantation Abroad: Too Much Unknown Yurtdişinda Akraba Olmayan Canlidan Yapilan Böbrek Nakli: Birçok Bilinmeyen Var

ObjecTIve: Despite the unethical characteristic and unfavorable consequences, paid livingunrelated renal transplantation is still considered as an option for end-stage renal disease patients. This study aimed to compare the medical and surgical complications along with allograft functions of PLURT patients with age and gender matched transplant recipients who received a living or deceased donor kidney at our center. mATerIAl and meTHOdS: End-stage renal disease patients received PLURT (group 1) in a foreign country and age, and gender matched renal transplant recipients that received renal transplantation from living-related donors (LRT patients; group 2) and deceased donors (DDRT patients; group 3) followed between 2003-2010 at our transplantation center were included in the study. reSul TS: There were no significant differences between groups (Group 1&2 and group 1&3) regarding age, sex, urea, creatinine, creatinine clearance, and proteinuria. Data about patients that received renal transplantation from living-related and deceased-donors at our center were sufficient when compared with PLURT patients. PLURT has a negative impact on patients’ survival because of surgical and medical problems. cOncluSIOn: In the present study, PLURT, LRT and DDRT patients had early and late complications of renal transplantation which were similarly seen in recent studies. The main problem for unfavorable results of PLURT is the commercial aspect of renal transplantation without considering the risks for ESRD patients.
Online Resources for Basal Cell Carcinoma

In this review, we analyze the strengths of online information sources that pertain to Basal Cell Carcinoma. In addition, we comment on the effect of this growing global database with regards to the patient doctor relationship. Finally, we examine the potential shortfalls in the value and the credibility of this growing information culture.
Influence of Exercise on Leptin, Adiponectin and Quality of Life in Type 2 Diabetics

Purpose: This study aimed to investigate the influence of aerobic exercise on the quality of life and leptin and adiponectin levels in patients with type 2 diabetes mellitus. Material and Method: Patients were randomized into two groups: aerobic exercise-training and control group. Parameters were assessed at baseline and end of the twelve-week follow-up for 60 type 2 diabetic patients who completed the program. The 36-item Short Form Health Survey was administered to the patients. Results: The exercise-training group results showed a decrease in adiponectin and leptin levels, a reduction of waist circumference and percentage of body fat (p=0.007, 0.023, 0.012 and 0.048, respectively). The leptin levels in the aerobic exercise group were positively correlated with body mass index (r=0.303, p=0.021) and percentage of body fat (r=0.371, p=0.005); they were negatively correlated with physical problems (r=-0.482; p=0.009) and pain (r=-0.540; p=0.003). Exercise led to statistically significant improvements in the SF-36 physical functioning and mental health subscales (p=0.020 and 0.023, respectively). Discussion: The association of better HbA1c, waist circumference, and percentage of body fat with improved mental and physical scores may be related to a decrease in leptin levels, despite a significant reduction in serum adiponectin levels. Turk Jem 2015; 19: 7-13
Monte Carlo techniques for patient specific verification of complex radiation therapy treatments including TBI, VMAT and SBRT lung

The main objective of this thesis is to develop Monte Carlo (MC) techniques for verification of complex radiation therapy treatments with emphasis on total body irradiation (TBI) and Volumetric modulated arc therapy (VMAT). This work was motivated by an initial study including ten non-small cell lung cancer (NSCLC) patients which evaluated the dosimetric consequences of plans optimized using the treatment planning system (TPS) by recalculating them with MC. It was shown that poor modelling of electronic disequilibrium by the TPS lead to underdosage of the planning target volume (PTV) and that quality assurance (QA) procedures should be based on a MC approach. With the emergence of volumetric modulated arc therapy (VMAT), which is a complex type of treatment delivery, new developments in MC simulations are required. A patient specific MC based QA system for VMAT treatments was developed and implemented clinically. This system is able to assess machine delivery performance and dose calculation accuracy of the TPS. During a substantial portion of the treatment the radiation beam is attenuated by the treatment couch. The impact of the attenuation on QA results is found to be patient specific and is non negligible. A process to create a couch model for MC simulations and its implementation is presented. The accuracy of this system is demonstrated against experimental measurements. For TBI the most important contributors to mortality is interstitial pneumonitis (IP). Adequate lung shielding and accurate estimation of lung doses is critical to reduce incidence of IP. A MC based TBI verification system including all the treatment delivery characteristics as well as patient specific lung compensators is presented. For the purposes of treatment plan quality improvement, a study including five anonymized image data sets from previously treated patients is performed. It is shown that mean doses to lungs are systematically larger for the prone position treatment compared to the supine position due to anatomical deformation. Improvement in dose distribution is investigated using a new fast inverse dose optimization algorithm combined with a
Application specific programmable processors for reconfigurable self-powered devices

The current Internet of Things solutions for simple measurement and monitoring tasks are evolving into ubiquitous sensor networks that are constantly observing both our well being and the conditions of our living environment. The oncoming omnipresent wireless infrastructure is expected to feature artificial intelligence capabilities that can interpret human actions, gestures and even needs. All of this will require processing power on a par with and energy efficiency far beyond that of the current mobile devices. The current Internet of Things devices rely mostly on commercial low power off-the-shelf micro-controllers. Optimized solely for low power, while paying little attention to computing performance, the present solutions are far from achieving the energy efficiency, let alone, the compute capability requirements of the future Internet of Things solutions. Since this domain is application specific by nature, the use of general purpose processors for signal processing tasks is counterintuitive. Instead, dedicated accelerator based solutions are more likely to be able to meet these strict demands. This thesis proposes one potential solution for achieving the necessary low energy, as well as the flexibility and performance requirements of the Internet of Things domain in a cost effective manner using reconfigurable heterogeneous processing solutions. A novel graphics processing unit-style accelerator for the Internet of Things application domain is presented. Since the accelerator can be reconfigured, it can be used for most applications of the Internet of Things domain, as well as other application domains. The solution is assessed using two computer vision applications, and is demonstrated to achieve an excellent combination of performance and energy efficiency. The accelerator is designed using an efficient and rapid co-design flow of software and hardware, featuring ease of development characteristics close to commercial off-the-shelf solutions, which also enables costefficient design flow.
Measuring student investment potential : a mixed methods approach

iv TABLE OF CONTENTS . vi LIST OF FIGURES . xiii LIST OF TABLES . xv LIST OF ACRONYMS . xvii CHAPTER 1: INTRODUCTION, PROBLEM STATEMENT AND OBJECTIVES OF THE STUDY . 1 1.
The Role of Platelet-rich Plasma in Charcot Foot Reconstruction

Growing interest exists regarding the surgical correction of diabetes-associated Charcot foot arthropathy. These patients are complicated by morbid obesity, multiple medical comorbidities, severe osteoporosis, and impaired wound healing. Knowledge of the high complication rates for wound failure, wound infection, or mechanical failure has stimulated interest in the use of statically applied circular external fixation. This presentation deals with the potential role of pooled platelet-derived growth factors (platelet-rich concentrate) and pluripotential stem cells (bone marrow aspirate), combined with circular external fixation in the treatment of this complex patient population.
L’insuffisance rénale aigue (IRA) chez l’enfant : aspects diagnostiques, thérapeutiques, évolutifs et pronostiques à propos de 50 cas colligés dans un service de pédiatrie à Dakar

Objectifs : Les objectifs de ce travailetaient de determiner les aspects diagnostiques, therapeutiques, evolutifs de l’IRA, et d’en evaluer le pronostic vital. Patients et methodes : Il s’agit d’une etude retrospective descriptive et analytique sur une periode de 06 ans.Ont ete inclus les patients de moins de 15 ans ayant une IRA definie par une elevation de la creatininemie superieure a 13 mg/l, evoluant depuis moins de 3 mois. Les donnees recueillies ont ete saisies et analysees avec le logiciel EXCEL2007. Resultats : Cinquante patients sur 5479 hospitalises ont ete inclus soit une prevalence hospitaliere de 0,91%. L’âge moyen etait de 6,95 ans et lesex-ratiode 2,33.Les signes cliniquesetaient domines par la pâleur des muqueuses chez 34 patients (68%), l’œdeme de type renal (68%), l’anurie (22%) etl’HTA (22%). La creatininemie moyenne de 83,48 mg/l±64,2. La ponction biopsie renale retrouvait cheztroispatientsune glomerulonephriteendo etextracapillaireet chez un patient, une necrose corticale. Le paludisme a Plasmodium falciparum etait diagnostique chez 24% des patients, la glomerulonephrite aigue post-infectieusedans 18% des cas et le reflux vesico-ureteral (RVU) chez 02 enfants (04%). Quatorze patients (28%) etaient hemodialyses.L’evolution favorable etait notee dans 58% des cas. Les facteurs de mauvais pronosticvitaletaient l’œdeme aigu du poumon, l’anurie et l’hyperkaliemie. Conclusion : Les causes infectieuses etaient les plus retrouvees. Le taux de letalite etait eleve. Nous recommandons la mobilisationde tous les moyens humains et techniques pour ameliorer le pronostic vital de l’IRA chez l’enfant. Mots cles : Enfants, Insuffisance renale aigue, Senegal
Gauging the Therapeutic Potential of β arrestin2 Targeting in Prostate Cancer

Copyright: © 2013 Lymperopoulos A. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Prostate cancer represents a devastating, male sex-specific form of cancer, accounting for approximately one-third of all male cancer cases in the United States alone [1]. This cancer often presents as androgen-dependent, hormone receptor-positive disease that can be successfully managed with targeted therapies aiming at disrupting the function of the Androgen Receptor (AR). Although these therapies are initially effective, a significant portion of the cancer patients develop advanced androgen-independent, hormone-refractory disease [2]. Thus, it comes as no surprise that effective management of prostate cancer is still highly needed to combat the high mortality rate that accompanies this disease [1]. The deregulation of expression and activity of AR and of its interacting protein partners are thought to be involved in the progression of prostate cancer to advanced disease [3,4]. The AR is a member of the nuclear hormone receptor superfamily (ligand-regulated transcription factors), modulating expression of multiple genes involved in the normal development and/or malignant transformation of the prostate gland [4-6].
Stoffwechselstörungen nach großen Dünndarmresektionen

Große Darmresektionen sind in der Regel Operationen der Not. Der Operateur ist nach der Eröffnung der Bauchhöhle in die Zwangslage versetzt, wegen Gangrän des Darms durch lnkarzeration, Invagination, Volvulus, Ruptura intestini, Abriß des Darms vom Mesenterium oder wegen Tumoren des Gekröses, multipler Strikturen u. a.einen großen Abschnitt des Darms abzutragen. Die Indicatio vitalis steht zunächst im Vordergrunde. Sind dann die Fährnisse der lebensbedrohlichen Erkrankung glücklich überwunden, so erhebt sich die Frage, welche Folgen für den Haushalt des Organismus durch die ausgedehnte Kürzung des Darmes zu erwarten sind. Die klinischen Erfahrungen stehen vielfach im Widerspruch, und auch im Tierversuch ist eine Reihe von Fragen noch nicht in wünschenswerter Klarheit beantwortet. Zunächst ist festzustellen, wieviel Dünndarm abgetragen werden kann, ohne die dauernde Erhaltung des Organismus zu gefährden. Da für den Menschen Resektionen größerer Abschnitte des Duodenums im allgemeinen nicht in Betracht kommen, ist imFolgenden unter Dünndarm Jejunum und Ileum zu verstehen. Senn gibt an, daß Katzen und Hunde nach Resektion von mehr als des gesamten Dünndarms früher oder später an Ernährungsstörungen zugrundegehen. Nach Trzebicky, Dilib erti-H erbin, Nagano ist es nach Abtragung von 2/3 und mehr vom Dünndarm unmöglich, die Tiere am Leben zu erhalten, während andere, wie Evans und Breniger, noch nach Fortnahme von 84,60/o des Intestinum tenue Lebensfähigkeit des Tieres annehmen. Monari gibt an, daß noch /8 des Dünndarms zur Ernährung und Erhaltung hinreicht, der gleichen Ansicht sind London und Dmitriew, während Soyesima glaubt, daß man Hunden bis zu 9O0/ des J ejunum-lleums ohne Schaden resezieren kann. Ich bin zunächst im Tierversuch folgenden Fragen nachgegangen: 1. Welchen Einfluß hat eine große Dünndarmresektion auf die Verdauungsund Resorptionsvorgänge?
Hospital-based KAP study on Diabetes in Bijapur, Karnataka

Background: India harbours the largest number of diabetic patients in the world. Poor awareness and practices are some of the important variables influencing the development and progression of diabetes and its complications, which are largely preventable. Preventive strategies need to be formulated based on factors contributing to the development and progression of diabetes. Knowledge, attitudes and practices among diabetics from backward areas of the country like Bijapur are not readily available. This study was undertaken to assess the knowledge, attitudes and practices regarding prevention and control of diabetes mellitus among patients attending the diabetic clinic at B.M. Patil Medical College and Hospital, Karnataka. Methods: A hospital based cross-sectional study in 730 type 2 diabetic patients aged ≥ 20 years was undertaken. Results: Mean age was 56.64 ± 11.38 years, 67% were males. 15.35% of respondents had poor, 59.9% average and 24.8% had good knowledge. Majority (60-90%) of the respondents had positive attitudes. 36.4% of the respondents were taking extra care in case they were injured and 40.7% were exercising regularly. Conclusions: Though good number of respondents had positive knowledge and attitude regarding diabetes, the same cannot be said about practices.