Miracle-dz/UniFAR-FTUs huggingface dataset:
Exposure to TiO2 nanoparticles improves the physiological characteristics of drought‐challenged chickpeas (Cicer arietinum L.)

Drought stress markedly affects plant growth and crop production. In turn, treatment with some metal‐based nanoparticles (NPs) such as TiO2‐NPs could improve the plant tolerance against drought stress. In the present study, the effects of different levels of moisture regime (40%, 60%, and 90% field capacity [FC]) in conjunction with various concentrations of TiO2‐NPs (0, 5, 10, 20, and 40 mg. L−1) on chickpea were studied. Exposure of drought‐challenged chickpea plants to TiO2‐NPs raised antioxidant enzyme activity compared with plants grown under drought without TiO2‐NP treatment. The highest activity of ascorbate peroxidase (APX) was observed at 40% FC and application of 40 mg. L−1 TiO2‐NPs. Moreover, peroxidase (POX) activity has increased with the enhancing concentration of TiO2‐NPs to 20 mg. L−1 at 90% FC. In comparison, the application of 40 mg. L−1 TiO2‐NPs and decreasing levels of FC caused a rise in the activity of superoxide dismutase (SOD). Exposure to TiO2‐NPs raised the amount of total phenols and 2,2‐diphenyl‐1‐picryl‐hydrazyl‐hydrate (DPPH) at different levels of moisture regime. The content of malondialdehyde (MDA) at 60% FC has decreased by 22% after treatment with 20 mg. L−1 TiO2‐NPs compared with control plants. Also, treatment with TiO2‐NPs heightened the proline content, and the highest amount of proline was obtained at 40% FC by applying 20 mg. L−1 NPs. The treatment with TiO2‐NPs in the moisture regimes led to higher chlorophyll and carotenoid production in chickpea plants. Taken together, the application of TiO2‐NPs could raise the defense potential of chickpea plants against oxidative stress caused by the generation of reactive oxygen species.
Revolutionizing hyperlipidemia treatment: Nanoencapsulated CoQ10 and selenium combat simvastatin-induced myopathy and insulin resistance in rats

Purpose: The objective of this study was to develop a nanoencapsulated platform for Coenzyme Q10 (coQNPs) or selenium (SeNPs) and explore their potential therapeutic benefits in treating hyperlipidemia and combating simvastatin-induced myopathy and adverse reactions in hyperlipidemic rats. Methods: The physical and chemical properties of the solid nanoparticles (SLNPs), coQNPs, and SeNPs were characterized, including zeta potential studies. Male Wistar albino rats were treated with various interventions for 112 days, including a nano-vehicle only, high-fat diet (HFD), HFD with simvastatin alone, or with coQNPs or/ and SeNPs for the last 30 days. Results: The coQNPs and SeNPs exhibited uniform spherical shapes with high encapsulation efficiency (EE% 91.20 ±2.14 and 94.89 ±1.54, respectively). The results demonstrated that coQNPs and SeNPs effectively reduced hyperlipidemia, insulin resistance, simvastatin-induced myopathy, and hepatotoxicity. However, combining simvastatin with coQNPs and SeNPs resulted in severe liver and muscle damage. Treatment with simvastatin and SeNPs or simvastatin and coQNPs alone showed significant improvements compared to simvastatin treatment alone. Conclusion: These findings suggest that the CoQNPs or SeNPs platforms offer advanced relief for hyperlipidemia and insulin resistance while limiting adverse effects such as myopathy and hepatotoxicity.
Data fusion of significant wave height from HY-2A and other satellite altimeters

The HY-2A (launched on 2011/8/16) is the first microwave marine remote sensing satellite from HY-2 satellite series developed by China. It includes a dual-frequency altimeter in Ku and C-bands. In this paper, (1) significant wave height (SWH) data from HY-2A altimeter are corrected by using collocated NDBC (U.S. National Data Buoy Centre) buoy data and are compared with Jason-1/2 data; (2) data fusion of SWH from the combination of HY-2A altimeter and other satellite altimeters (Jason-1/2 and Envisat) is given and the results are compared one another; (3) the merged SWH data from HY-2A, Jason-1/2 and Envisat are used to analyze the characteristics of SWH in China Seas and adjacent waters. Comparisons show that the results are good and HY-2A altimetry data work well with other satellite altimetry data.
Antioxidant Properties and Prediction of Bioactive Peptides Produced from Flixweed (sophia, Descurainis sophia L.) and Camelina (Camelina sativa (L.) Crantz) Seed Meal: Integrated In Vitro and In Silico Studies

Flixweed (sophia) seed meal and camelina, both by-products of oil processing, were employed to generate protein hydrolysates by applying Flavourzyme and Alcalase. This study aimed to integrate in vitro and in silico methods to analyze sophia and camelina protein hydrolysates for releasing potent antioxidative, dipeptidyl peptidase IV (DPP IV) inhibitors and angiotensin-converting enzyme (ACE) inhibitory peptides. In vitro methods were used to investigate the antioxidant potential of sophia/camelina protein hydrolysates. Bioinformatics techniques, including Peptideranker, BIOPEP, Toxinpred, AlgPred, and SwissADME, were employed to obtain the identification of bioactive peptides produced during the hydrolysis process. Protein hydrolysates produced from sophia and camelina seed meal exhibited higher ABTS and DPPH radical scavenging activities Ithan their protein isolates. Among the produced protein hydrolysates, Alcalase-treated samples showed the highest oxygen radical absorbance capacity and hydroxyl radical scavenging activity. In addition, sophia/camelina hydrolysates prevented hydroxyl and peroxyl radical-induced DNA scission and LDL cholesterol oxidation. In silico proteolysis was conducted on Alcalase-treated samples, and resultant peptides showed potential DPP IV and ACE-inhibitory activities. Identified peptides were further assessed for their toxicity and medicinal properties. Results indicate that all digestive-resistant peptides were non-toxic and had desirable drug-like properties. The findings of this study suggest that sophia/camelina protein hydrolysates are promising candidates for functional foods, nutraceuticals, and natural therapeutics.
Etudes hydrauliques de l'influence des géométries des bassins sur l'alimentation des pompes

Les travaux portent sur l'analyse des ecoulements qui se developpent dans les bassins d'alimentation de pompes. Les structures qui en decoulent sont generalement des tourbillons qui peuvent entrainer de l'air ou des particules solides comme les sediments. Ce probleme est generalement rencontre pour des applications d'irrigations, de captage des eaux usees et pour quelques applications marines. Les travaux presentent d'une part, des resultats experimentaux obtenus sur une configuration de bassin d'alimentation de pompes de forme rectangulaire. Plusieurs configurations geometriques sont testees et analysees en particulier celles qui traitent de l'influence de l'immersion du tuyau d'alimentation et de sa position entre les murs lateraux. D'autres parts, une analyse basee sur une modelisation numerique de type RANS, permet de comprendre certains phenomenes, pour des configurations bien documentees qui ont egalement fait l'objet de resultats publies. L'etude numerique est ensuite etendue a d'autres configurations en particulier pour detecter l'influence relative de certains parametres geometriques juges importants pour modifier les structures d'ecoulements dans ces bassins
Building Low-Cost, High-Performance Flexible Photodetector Based on Tetragonal Phase VO2 (A) Nanorod Networks

We present a straightforward and cost-effective method for the fabrication of flexible photodetectors, utilizing tetragonal phase VO2 (A) nanorod (NR) networks. The devices exhibit exceptional photosensitivity, reproducibility, and stability in ambient conditions. With a 2.0 V bias voltage, the device demonstrates a photocurrent switching gain of 1982% and 282% under irradiation with light at wavelengths of 532 nm and 980 nm, respectively. The devices show a fast photoelectric response with rise times of 1.8 s and 1.9 s and decay times of 1.2 s and 1.7 s for light at wavelengths of 532 nm and 980 nm, respectively. In addition, the device demonstrates exceptional flexibility across large-angle bending and maintains excellent mechanical stability, even after undergoing numerous extreme bending cycles. We discuss the electron transport process within the nanorod networks, and propose a mechanism for the modulation of the barrier height induced by light. These characteristics reveal that the fabricated devices hold the potential to serve as a high-performance flexible photodetector.
Study of long‐term trend in aerosol optical thickness observed from operational AVHRR satellite instrument

[1] The long-term trend of aerosol optical thickness (AOT) over the global oceans has been studied by using a nearly 25-year aerosol record from the Advanced Very High Resolution Radiometer (AVHRR) Pathfinder Atmosphere extended (PATMOS-x) data set. Both global and regional analyses have been performed to derive the AOT tendencies for monthly, seasonal, and annual mean AOT values at AVHRR 0.63 μm channel (or Channel-1). A linear decadal change of −0.01 is obtained for globally and monthly averaged aerosol optical thickness, τ1, of AVHRR Channel-1. This negative tendency is even more evident for globally and annually averaged τ1 and the magnitude can be up to −0.03/decade. Seasonal patterns in the AOT regional long-term trend are evident. In general, negative tendencies are observed for seasonally averaged τ1 in regions influenced by emissions from industrialized countries and the magnitude can be up to −0.10/decade. Positive tendencies are observed in regions influenced by emissions from fast developing countries and the magnitude can be up to +0.04/decade. For regions heavily influenced by Saharan desert particles, a negative trend with a maximum magnitude of −0.03/decade is detected. However, over regions influenced by smoke from biomass burning, positive tendencies with a maximum magnitude of +0.04/decade are observed. Sensitivity analyses have also been performed to study the effects of radiance calibration, aerosol retrieval algorithm, and spatial resolution of input retrieval radiances on the global aerosol long-term tendencies.
On Slaty Cleavage (second communication)

In a paper read to the Geological Society on the 2nd of December 1846, on the cleavage of slate rocks, I endeavoured to work out certain general laws relative to the compression which such rocks had undergone, to the position of the planes of cleavage, and to the connection between their direction and the elevation of the beds. The conclusions were founded upon observations chiefly made in North Wales, Devonshire and Cornwall: I have since visited parts of West-moreland and Cumberland, with the view of enlarging the field of observation, and the result is contained in the following remarks, which are thrown into the order adopted in the former paper. Compression of slate-rocks in a direction perpendicular to the planes of cleavage. —In the former paper, p. 87, I stated that in all the slaty fossiliferous rocks examined, the distortion of the fossils proved that the mass of the rocks had undergone considerable compression in a direction everywhere perpendicular to the planes of cleavage, and some expansion in the direction of the dip of the cleavage; but that there was no reason to suppose that the rocks had suffered any change of volume in the direction of the strike of the cleavage. And it was inferred that these changes must be general in all slaty rocks, although it might not be easy to find proofs that they had occurred, where organic remains were absent. There is however more evidence of compression to be found among the beds of unfossiliferous slate than
Intelligent Framework for Early Detection of Severe Pediatric Diseases from Mild Symptoms

Children’s health is one of the most significant fields in medicine. Most diseases that result in children’s death or long-term morbidity are caused by preventable and treatable etiologies, and they appear in the child at the early stages as mild symptoms. This research aims to develop a machine learning (ML) framework to detect the severity of disease in children. The proposed framework helps in discriminating children’s urgent/severe conditions and notifying parents whether a child needs to visit the emergency room immediately or not. The model considers several variables to detect the severity of cases, which are the symptoms, risk factors (e.g., age), and the child’s medical history. The framework is implemented by using nine ML methods. The results achieved show the high performance of the proposed framework in identifying serious pediatric diseases, where decision tree and random forest outperformed the other methods with an accuracy rate of 94%. This shows the reliability of the proposed framework to be used as a pediatric decision-making system for detecting serious pediatric illnesses. The results are promising when compared to recent state-of-the-art studies. The main contribution of this research is to propose a framework that is viable for use by parents when their child suffers from any commonly developed symptoms.
Comparative Study of Artificial Intelligence Detection Technology from Exception Ischemic Stroke Requiring Medical Help Imaging

Artificial intelligence is revolutionizing the interpretation of medical images, helping healthcare professionals save time on magnetic scans, CT scans and X-rays. Stroke is a global health problem, and ischemic stroke is one of the leading causes of death and disability in humans. Symptoms of an ischemic stroke appear suddenly and worsen within minutes, as most ischemic strokes occur suddenly, progress rapidly, and lead to the death of brain tissue within minutes or hours. This is why early detection of stroke is essential and remains a challenge for neurophysicists. Neurophysicists routinely use a variety of detection techniques to detect, assess and evaluate the ex-tent of premature ischemic changes in acute stroke brain imaging. Although several effective techniques exist, these methods have limitations due to unenhanced CT scans and invasive techniques. This study aims to demonstrate the limitations of certain methods, to determine detection methods by comparing the detection performance of automated and human brains. Stroke was evaluated through a literature review of recent studies.This article highlights comparative studies of different artificial intelligence (AI) techniques using medical imaging and allows the authors to orient themselves within these comparative studies, thus projecting themselves into the challenges facing artificial intelligence.
Inflammation-Related Immune-Modulatory SLURP1 Prevents the Proliferation of Human Colon Cancer Cells, and Its Delivery by Salmonella Demonstrates Cross-Species Efficacy against Murine Colon Cancer

This study investigates the anticancer properties of the α7-nAChR antagonist SLURP1 with a specific focus on its effect as an inflammation modulator on human colorectal cancer cell lines Caco2, Colo320DM, and H508 cells. The investigation includes the evaluation of cell cycle arrest, cell migration arrest, endogenous expression of SLURP1 and related proteins, calcium influx, and inflammatory responses. The results demonstrate that SLURP1 not only inhibits cell proliferation but also has the potential to arrest the cell cycle at the G1/S interface. The impact of SLURP1 on cell cycle regulation varied among cell lines, with H508 cells displaying the strongest response to exogenous SLURP1. Additionally, SLURP1 affects the nuclear factor kappa B expression and effectively reverses inflammatory responses elicited by purified lipopolysaccharides in H508 and Caco2 cells. This study further confirmed the expression of human SLURP1 by Salmonella, under Ptrc promoter, through Western blot analysis. Moreover, Salmonella secreting SLURP1 revealed a significant tumor regression in a mouse CT26 tumor model, suggesting the cross-species anticancer potential of human SLURP1. However, further investigations are required to fully understand the mechanisms underlying SLURP1’s ability to prevent cancer proliferation and its protective function in humans.
Late Archaean to Palaeoproterozoic evolution of the Trans-North China Orogen: insights from synthesis of existing data from the Hengshan-Wutai-Fuping belt

Abstract The Hengshan-Wutai-Fuping mountain belt constitutes the middle segment of the Trans-North China Orogen, which separates the North China Craton into the Eastern and Western Blocks. The belt consists of the high-grade Hengshan and Fuping complexes, and the intervening low- to medium-grade Wutai Complex. Previous tectonic models assumed that the high-grade complexes were an older basement (Archaean to Palaeoproterozoic) to the low-grade Wutai Complex. However, new geochronological data show that the emplacement of granitoid rocks and eruption of volcanic rocks in the Wutai Complex occurred essentially coeval with or slightly earlier than intrusion of the tonalitic-trondhjemitic-granodioritic (TTG) suites in the Hengshan and Fuping complexes. New isotopic data also reveal the widespread presence of Palaeoproterozoic granitoid rocks in these complexes. Structural and metamorphic data demonstrate similar tectonothermal histories for the three complexes, which are characterized by peak medium- to high-pressure metamorphism accompanied by the development of thrusting, isoclinal folding (F2) and penetrative foliations, followed by near-isothermal decompression and cooling and retrogression associated with the formation of large-scale ductile shear zones and asymmetrical folds (F3) with nearly vertical axial planes. These geochronological, structural and metamorphic data suggest that the tectonic evolution of the Hengshan-Wutai-Fuping mountain belt may not be related to local interaction of the three complexes, as suggested in earlier models, either through closure of a Wutai rift or collision between a Wutai arc and the Hengshan and Fuping micro-continental blocks. Instead, they may represent elements of a single Late Archaean to Early Palaeoproterozoic magmatic arc that was subsequently incorporated into the Trans-North China Orogen along which the Eastern and Western blocks amalgamated to form the North China Craton at around 1.85 Ga.
Metamorphic grade of source rocks revealed by chemical fingerprints of detrital amphibole and garnet

Abstract Amphibole and garnet are among the most widespread heavy minerals in orogenic sediments. Their chemical composition and optical properties vary markedly and systematically with temperature and pressure conditions during growth, and thus provide important information on the metamorphic evolution of source areas that is crucial in palaeotectonic and palaeogeodynamic reconstructions. This study investigates the chemical composition of detrital amphiboles and garnets derived from parent rocks of progressively increasing metamorphic grade through a well-studied composite section across the Central and Southern Alps, including the granulite-facies core of the Late Palaeozoic orogen exposed in the Ivrea–Verbano Zone and the amphibolite-facies core of the Cenozoic orogen exposed in the Lepontine Dome. We specifically focus on metamorphic grade because it represents the best proxy for tectono-stratigraphic crustal level, and hence degree of unroofing of source areas. In river sands collected between metamorphic isograds corresponding to crystallization temperatures ranging from c. 500 °C to c. 850 °C, TiO2 gradually increases in detrital amphibole while its colour progressively changes from blue-green in the lower amphibolite-facies where actinolite, hornblende and tschermakite are most abundant, to brown in the granulite facies where pargasite is dominant. Detrital garnets display moderate gradual changes across the amphibolite-facies Lepontine Dome, where low-Mg ‘type B’ garnets predominate. Almandine-spessartine is spatially associated with abundance of pegmatites while entering the zone of anatexis (Southern Steep Belt), where grossular or grossular-andradite-spessartine are occasionally found. A sharp change occurs while reaching granulite-facies in the Ivrea–Verbano Zone, where high-Mn garnets disappear and ‘type A’ almandine-pyrope (from ‘stronalite’ metasediments) and ‘type C’ almandine-pyrope-grossular (from metagabbros of the Mafic Complex) predominate. Also redefined in this article are a series of numerical indices based on amphibole colour and relative abundances of diverse key minerals (chloritoid, staurolite, andalusite, kyanite, fibrolitic and prismatic sillimanite), useful to accurately assess the average metamorphic grade of meta-igneous and metasedimentary source rocks. Supplementary material: Chemical composition of detrital amphiboles and garnets and full information on the location and mineralogical composition of studied samples is available at http://www.geolsoc. org.uk/SUP18618.
The role of perceived risk as a moderating variable: Customer data, IndiHome Telkom Surabaya city

This study aims to find out how perceived risk acts as a moderating variable, and how the quality of information systems, service quality, and perceived trust affect customer satisfaction of IndiHome Telkom users in the city of Surabaya. This study employs a structural equation model data collected from 385 respondents who were selected using a purposive sampling method. The respondents were drawn from the population of IndiHome Telkom users residing in the city of Surabaya. The sample criteria are customers who have used IndiHome for at least 3 months, and are at least 17 years old. The findings indicate that the perceived risk is with a positive moderator. Perceived trust serves as a constructive mediating factor in the association between information system quality and service quality which ultimately influence customer satisfaction. Research also proves that information system quality, service quality and perceived trust make a positive contribution to customer satisfaction. This study concludes that perceived risk with a transactional process does not harm consumers rather it strengthens consumer’s satisfaction. These findings can be used to attract more Indihome Telkom customers in Surabaya, by increasing perceived trust and reducing perceived risk. It is recommended that Telkom improves network quality and computer hardware quality. This will have a positive impact on the satisfaction of IndiHome Telkom users.