Miracle-dz/UniFAR-FTUs huggingface dataset:
ASSESSMENT OF RISK FACTORS OF OSTEOPOROTIC FRACTURES AMONG EGYPTIAN PATIENTS

Aim: To study and assess the risk factors for fractures in the osteoporotic Egyptian patients older than 40 years. Methods: Forty eight persons (> 40 years old) were included. They underwent complete clinical evaluation and laboratory analyses of serum calcium ( Ca +2 ) and vitamin D ( Vit. D ) levels, with assessment of the bone mineral density (BMD) using the Dual Energy X-ray Absorptiometry scanner (DEXA). They were divided into two groups: a patients’ group including 27 osteoporotic patients having fractures and a control group including 21 osteoporotic cases without fractures. Results: The percentage of females was higher in both groups (74.1% and 61.9%. p=0.36). The mean age was significantly higher in the patients’ group (mean ± SD 62.11 ± 6.6 vs 53.48 ±6.7 years), while the mean height was significantly lower (p<0.05). The weight and body mass index (BMI) were comparable between both groups (p>0.05). About 70.4% of osteoporotic patients had their fractures from minor traumas; meanwhile the control had no fractures even with minor or moderate traumas. The T-score, Z-score and the BMD were significantly lower in the patients (p<0.05). In addition, Vit. D and Ca +2 levels were significantly lower (p<0.05). A positive family history of fractures was significantly higher in the patients (p=0.013), while no other risk factor was significantly different between both groups. Conclusion: An advanced age, a short stature, a positive family history, traumas, and low Vit. D and Ca +2 levels are major risk factors associated with a low BMD and osteoporotic fractures in the adult Egyptian population.
The Predictive Value of Changes in the Absolute Counts of Peripheral Lymphocyte Subsets for Progression and Prognosis in Breast Cancer Patients

Background As the number and proportion of lymphocyte subsets are an important indicator of the immune function, an in depth understanding of the immune function of patients with malignant tumor has important clinical values for the treatment, prognosis, and evaluation of the disease. This retrospective study was to evaluate the clinical value of the absolute counts of lymphocyte subsets as potential blood biomarkers for progression and prognosis in breast cancer patients. Methods A total of 237 BC patients and 55 age-matched female normal healthy donors were included in this study. Flow cytometry was used to determine the absolute counts and the percentages of CD3+, CD4+, CD8+, B, and NK cells. The receiver operating characteristic curve (ROC) was used to evaluate the accuracy of absolute count of lymphocyte subsets in the curative efficacy assessment. The clinicopathological parameters influencing the disease progression were determined by Cox proportional hazards regression. Progression-free survival (PFS) was estimated using the Kaplan–Meier method with the log-rank test. Results: Compared with the healthy donors, the absolute counts of lymphocyte subsets in patients decreased significantly. ROC analysis showed that the area under the curve of the CD4+ absolute count was 90% (95% confidence interval 0.859–0.940), and the sensitivity and specificity were 80.9% and 85.3%, respectively. The analysis of Cox regression showed that the cutoff value of the CD4+ absolute count ≥451 cells/μL might be a favorable prognostic factor. Multivariate analysis of prognostic factors of PFS showed that the CD4+ and CD8+ absolute count were independent factors for predicting PFS. Conclusions The remarkably impaired absolute counts of the CD3+, CD4+, CD8+, B, and NK cells in patients with breast cancer can be used as potential susceptible biomarkers to evaluate the patient's immune status. The higher level of CD4+ and CD8+ absolute counts probably contributed to the longer PFS and favorable outcome of BC patients.
Sectoral Financing Concentration and Profitability of Islamic Banking in Indonesia

This paper investigates the extent to which sectoral financing concentration affects the Islamic banks' profitability in Indonesia. As additional control variables, we include bank-specific and macroeconomic conditions. This study utilizes the aggregated financial statements of Islamic banks in Indonesia from January 2010 through December 2019 and analyzed with the Autoregressive distributed lag (ARDL) model. The results confirm cointegration evidence, demonstrating the long-term relationship between the dependent and independent variables. The results clearly indicate that sectoral financing concentration increases the profitability of Islamic banks. Furthermore, excessive financing and high non-performing financing reduce the profitability of Islamic banks. As a financial sector, Islamic banks' performance is contingent on favorable economic and macroeconomic conditions, such as high economic growth and low inflation. These findings imply that Islamic banks must employ skilled workers who are experts in related economic sectors, which is one of the primary goals of Islamic bank financing. ========================================================================================================== ABSTRAK – Konsentrasi Pembiayaan Sektoral dan Profitabilitas Bank Syariah di Indonesia. Tulisan ini mengkaji sejauh mana konsentrasi pembiayaan sektoral mempengaruhi profitabilitas bank syariah di Indonesia. Sebagai variabel kontrol tambahan, kami menyertakan kondisi spesifik bank dan variabel makroekonomi. Penelitian ini menggunakan agregat laporan keuangan bank syariah di Indonesia dari Januari 2010 sampai Desember 2019 dan dianalisis dengan model Autoregressive distributed lag (ARDL). Hasil kajian mengkonfirmasi bukti kointegrasi, yang menunjukkan hubungan jangka panjang antara variabel dependen dan independen. Hasil kajian memperjelas bahwa konsentrasi pembiayaan sektoral dapat meningkatkan profitabilitas bank syariah, sementara pembiayaan yang berlebihan dan pembiayaan bermasalah yang tinggi mengurangi profitabilitas bank syariah. Sebagai institusi yang bergerak di sektor keuangan, kinerja bank syariah sangat bergantung pada kondusifitas sistem ekonomi dan kondisi makroekonomi, seperti pertumbuhan ekonomi yang tinggi dan inflasi yang rendah. Temuan ini menyiratkan bahwa bank syariah harus mempekerjakan pekerja terampil yang ahli di sektor ekonomi terkait, yang merupakan salah satu tujuan utama pembiayaan bank syariah.
Frequency and Prognostic Significance of Intertumoural Heterogeneity in Multifocal Jejunoileal Neuroendocrine Tumours

Simple Summary Well differentiated jejunoileal neuroendocrine tumors (SI-NETs) commonly present as multiple primaries, which are believed to be clonally unrelated. Our study aimed to explore whether these multifocal lesions show intertumoral differences between the most common histomorphological parameters and if so, whether these differences can be associated with patient prognosis. While WHO grade and standard neuroendocrine markers were found to be mostly stable, we observed intertumoral heterogeneity in the expression of SSTR2, CDX2, and serotonin, but observed no survival differences between the expression groups or in comparison to unifocal NETs. Although multifocal SI-NETs showed some degree of heterogeneity in their central morphological parameters, these findings do not appear to be of major clinical significance, rendering an extensive testing of all multifocal lesions as not necessarily required. Abstract Background: A recent study found that multifocal jejunoileal neuroendocrine tumors (SI-NETs) are genetically unrelated synchronous neoplasms. So far, it is unclear if this finding of synchronous independent neoplasms is mirrored by heterogeneity of key morphological parameters of SI-NETs and how it affects patient survival. Methods: We separately assessed WHO grade (based on the Ki-67 index), expression of basal diagnostic markers (synaptophysin/chromogranin A/CDX2/serotonin), SSTR2a, and the contexture of the immunogenic microenvironment in 146 separate tumors from 28 patients with multifocal SI-NETs and correlated the results with clinicopathological factors and survival. Results: Synaptophysin and chromogranin A were strongly expressed in all tumors. WHO grade was concordant within all multifocal lesions in more than 80% of cases and the highest grade was usually found in the most advanced primary. Intertumoral expression of serotonin, SSTR2, and CDX2 was discrepant in 32%, 43%, and 50% of all patients, respectively. Neither heterogeneity of any of the aforementioned markers nor multifocality itself had any impact on patient survival (p = n.s.). Discussion: Multifocal SI-NET show considerable variability in some of the central diagnostic parameters. However, neither intertumoral heterogeneity of those parameters nor multifocality itself had any impact on patient survival, showing that extensive testing of all multifocal lesions is not necessarily required.
The Impact of Artisanal Mining on Career Development of Adolescents in Zimbabwe

The research explored the impact of artisanal mining on the career development of adolescents at three selected schools in Imbizo District, Bulawayo Metropolitan Province. Interpretivism research philosophy was employed in the study, and a qualitative research method was used. The phenomenological research design was adopted for the study. The sample comprised fifteen school children aged between 14 to 20 years, and six teachers were selected from schools in Imbizo district in Bulawayo province, Zimbabwe, using purposive sampling. Due to COVID-19 regulations, interviews were telephonically, and focus group discussions were conducted online. Interviews were used to collect data from children, while focus group discussions were used to collect data from teachers. The findings revealed that causes of child involvement in artisanal mining include influence from society, poverty, drugs, adventure and the COVID-19 outbreak. The research findings revealed that child involvement in mining brought undesirable behavioural traits such as anti-social behaviour, poor academic performance, health and safety risks and different forms of abuse. Strategies suggested by teachers to mitigate child involvement in illegal mining encompassed legalising the small-scale mines, life skills education, educational support to all vulnerable children, community awareness campaigns, non-governmental organisations (NGOs) and government involvement. The children suggested that the government could help by providing them with basic needs like food and paying for their schools and stationery.
Immune Response and Immunobiology COVID-19 (Coronavirus Disease 2019)

SARS-CoV-2 not only activates an antiviral immune response but can also cause an uncontrolled inflammatory response characterized by the marked release of proinflammatory cytokines in patients with severe COVID-19, leading to lymphopenia lymphocyte dysfunction, and granulocyte and monocyte abnormalities. The immune pattern of COVID-19 includes lymphopenia, lymphocyte activation and dysfunction, granulocyte and monocyte abnormalities, increased cytokine production, and increased antibodies.
Effect of Simulation-Based Education on Nurses' Performance and Satisfaction regarding Peripherally Inserted Central Catheters at Neonatal Intensive Care Unit

Background : Peripherally inserted central catheter is an essential device used frequently in neonatal intensive care units for critically ill neonates who need continuous monitoring and resuscitation treatments. Simulation-based education serves as a link between classroom learning and clinical practice. It aids nursing competency before working with neonates in a real-life environment, hence improving the quality of care and ensuring neonates' safety. This study aimed to: evaluate the effect of simulation-based education on nurses' performance and satisfaction regarding peripherally inserted central catheters in the Neonatal Intensive Care Unit. Subject and Method : Design : A quasi-experimental research design was used. Setting : The study was conducted in the Neonatal Intensive Care Unit affiliated to Sohag University Hospital. Subjects : all nurses (50) who are working in the neonatal intensive care unit. Tools for data collection: (1) peripherally inserted central catheter questionnaire sheet, (2) observational checklist, and (3) nurses' satisfaction scale was used to collect data. Results : There was a highly statistically significant difference between the studied nurses' knowledge, practice, and satisfaction. The study result revealed that more than two-thirds of studied nurses had a poor level of knowledge, and more than half of them had an unsatisfactory level of practice about peripherally inserted central catheters before implementation of the simulation-based education. The vast majority of the studied nurses had a good level of knowledge and most of them had a satisfactory level of practice after implementing simulation-based education . There was a highly statistically significant difference and improvement in nurses' performance after simulation-based education than pre-education. Conclusion : The present study concluded that simulation-based education had a positive effect on improving nurses' performance and satisfaction regarding peripherally inserted central catheters. Recommendations : The study recommended that simulation-based education should be integrated as an effective method in nurses' training about peripherally inserted central catheters.
Revisiting radiant cooling: condensation-free heat rejection using infrared-transparent enclosures of chilled panels

ABSTRACT In this study, we enhance the understanding and design of a radiant cooling technology for outdoor comfort in tropical climates, originally proposed by R.N. Morse in 1963, in this journal. We investigate a type of radiant cooling methodology whereby the cold temperature source is physically separated from the outdoor environment by an insulated enclosure using a membrane transparent to infrared radiation. The enclosure isolates the radiant cooling surface from ambient conditions, allowing the radiant surface to be cooled significantly below ambient dew point temperatures without incurring condensation. For this new study, a Fourier Transform Infrared (FTIR) Spectroscopy analysis on three candidate membrane materials is undertaken and a prototype experimental test panel is fabricated. Our study shows that for a 5°C chilled panel temperature, the exterior membrane surface temperature reaches 26°C in a 32°C / 70% RH environment resulting in an effective mean radiant temperature of 15.8°C. These results provide new evidence in support of Morse's original proposal, that such panels could provide significant radiant cooling without condensation in humid environments. Radiant cooling products based on the studied technology may offer an ability to provide thermally comfortable conditions in hot environments without the energy required for dehumidification.
Photometric analysis of astronomical images by the wavelet transform

An application of the wavelet analysis to astronomical images is presented. It is shown that this new method is a powerful tool for the detection of features whose scales are known. The detection is easy and accurate because, in a wavelet analysis, the effect of the background is removed. If a model is fitted to the objects, photometric data can be deduced from the parameters of the wavelet transform. If Gaussian models fit to the objects and to the point-spread function, the process is analytical. To extend the method to other models, numerical simulations have to be performed
Orders and overlapping clusters by pyramids

HAL is a multi-disciplinary open access archive for the deposit and dissemination of scientific research documents, whether they are published or not. The documents may come from teaching and research institutions in France or abroad, or from public or private research centers. L’archive ouverte pluridisciplinaire HAL, est destinée au dépôt et à la diffusion de documents scientifiques de niveau recherche, publiés ou non, émanant des établissements d’enseignement et de recherche français ou étrangers, des laboratoires publics ou privés. Orders and overlapping clusters by pyramids E. Diday
A Connection between Rasch's Item Analysis Model and a Multiplicative Poisson Model

Introduction of random row effects in Rasch's item analysis model (or the two-way logit-additive model for binary data), followed by a (not very controversial) extension of this model leads to a model which is shown to be equivalent to a conditional multiplicative Poisson model. This result gives some new insight in the structure of Rasch's model and suggests some goodness of fit tests which are applicable also to the original "fixed effects" Rasch model.
The Spatial and Temporal Evolution of the Coordination Degree in Regard to Farmland Transfer and Cultivated Land Green Utilization Efficiency in China

In many parts of the world, the shortage of cultivated land and the food crisis are worsening on a continued basis. Hence, the central and local governments of the PRC have successively issued various related policies to encourage the practice of farmland transfer, promote the eco-friendly utilization of cultivated land, and ameliorate the efficiency of cultivated land utilization. Under the context of large-scale farmland transfer and rural revitalization strategy in China, it is significant to ensure agricultural sustainability through the coordination of farmland transfer and the amelioration of cultivated land green utilization efficiency (CLGUE). In the present study, 30 Chinese provinces were taken as the research object, with the super-efficient SBM model, the coupling coordination degree model and the spatial analysis model applied in combination. Based on the measurement of CLGUE, a thorough analysis was conducted to explore the evolution of coordination degree in regard to farmland transfer and CLGUE in China from both spatial and temporal perspectives. The conclusions drawn from this study are as follows. Firstly, the overall CLGUE exhibited an upward tendency in the PRC, from 0.440 in 2005 to 0.913 in 2019, with a yearly growth rate of 5.47% on average. However, there were significant spatial disparities in CLGUE between different regions and provinces. Secondly, there was a steady increasing trend shown by the level of coordination degree regarding farmland transfer and CLGUE across China. Further, due to the variation in natural and economic conditions, there were significant spatial–temporal disparities in the coordination degree among these 30 provinces. Lastly, there were obvious spatial aggregation patterns at the provincial level regarding the coordination degree in farmland transfer and CLGUE across China. However, there was a declining trend in the level of spatial aggregation patterns for coordination degree.
Knockdown of p-Coumaroyl Shikimate/Quinate 3′-Hydroxylase Delays the Occurrence of Post-Harvest Physiological Deterioration in Cassava Storage Roots

Cassava storage roots are an important source of food, feed, and material for starch-based industries in many countries. After harvest, rapid post-harvest physiological deterioration (PPD) reduces their palatability and marketability. During the PPD process, vascular streaking occurs through over-accumulation of coumarins, the biosynthesis of which involves the key enzyme p-coumaroyl shikimate/quinate 3′-hydroxylase (C3′H). Repression of MeC3′H expression by RNA interference in transgenic cassava plants caused a significant delay in PPD by decreasing scopoletin and scopolin accumulation in field-harvested storage roots. This study demonstrates that MeC3′H is the key enzyme participating in coumarin biosynthesis during PPD and shows that MeC3′H is a useful target gene for editing to prolong the shelf life of cassava storage roots.
Computed tomography-guided Sens-cure needle localization for scapular-blocked lung nodules

Introduction The use of preoperative computed tomography (CT) to guide the wedge resection (WR) of lung nodules (LNs) in video-assisted thoracoscopic surgery (VATS) is widely accepted. However, some LNs may be blocked by the scapula and a trans-scapular approach should be used when performing the localization procedures. Aim To investigate the feasibility, safety, and clinical effectiveness of preoperative CT-guided Sens-cure needle (SCN) localization for scapula-blocked LNs (SBLNs). Material and methods One hundred and eighty patients with LNs who had undergone CT-guided SCN localization before VATS were enrolled in this single-center retrospective study from January 2018 to December 2021. Ten of these patients (5.6%) had SBLNs and underwent localization using the trans-scapular approach. The technical success of localization, together with complications and VATS, was assessed. Results Data on the 10 patients with 10 SBLNs were analyzed. Scapular puncture was successful in all patients (100%) with no incidence of complications near the scapula. SCN localization was also successful in 100% of patients. The average duration of SCN localization was 12.5 ±4.0 min, with 1 (10%) patient experiencing pneumothorax after localization. The WR success rate was also 100%. Three patients underwent additional lobectomy due to invasive adenocarcinoma. The VATS procedure lasted on average for 97.0 ±56.0 min with an average blood loss of 44.0 ±35.0 ml. Conclusions Preoperative CT-guided SCN localization using the trans-scapular approach is safe, effective, and highly successful for VATS-guided WR of SBLNs.
Effect of Educational Program regarding Hyperemesis Gravidarum on Nurses′ Performance and Women's Outcomes

Background: Hyperemesis gravidarum refers to prolonged and excessive nausea and vomiting resulting in undesirable maternal and fetal health outcomes, which require hospital admission and extensive medical and nursing care. So, there is an urgent need to increase nurses' performance regarding hyperemesis gravidarum. Aim: The present study aimed to determine the effect of educational program regarding hyperemesis gravidarum on nurses′ performance and women′s outcomes. Subjects and method: Setting: This study was conducted at antenatal units of obstetric departments of Tanta University hospital affiliated to Ministry of High Education, El-Menshawy hospital affiliated to Ministry of Health and Population and EL-Mabara hospital affiliated to Health Insurance. Subjects: The study included all nurses (48 nurses) who are working in the previously mentioned settings, and 144 pregnant women diagnosed with hyperemesis gravidarum during the first trimester of their pregnancy. The studied pregnant women were divided randomly into 3 groups (48 women in each group) pre, immediately post and three months post implementation of the educational program. Three tools were used to collect the data of this study: Tool I: Structured interview schedule for nurses and women, Tool II: An obs ervational checklist for nurses′ practice, and Tool III: Women′s outcomes assessment sheet. Results: The studied nurses' knowledge and practice regarding hyperemesis gravidarum as well as women′s outcomes were improved immediately and three months post implementation of the educational program. Conclusion: The findings of the present study revealed significant improvement in the nurses' performance immediately and three months post implementation of the educational program regarding hyperemesis gravidarum. Recommendations: the study recommended developing continuous educational programs for nurses to enhance and update their performance regarding hyperemesis gravidarum.