Miracle-dz/UniFAR-FTUs huggingface dataset:
The turbulence driving parameter of molecular clouds in disc galaxies

Supersonic turbulence plays a pivotal role during the formation of molecular clouds and stars in galaxies. However, little is known about how the fraction of compressive and solenoidal modes in the velocity field evolves over time and how it depends on properties of the molecular cloud or the galactic environment. In this work, we carry out magnetohydrodynamical simulations of disc galaxies and study the time evolution of the turbulence driving parameter for an ensemble of clouds. We find that the time-averaged turbulence driving parameter is insensitive to the position of the cloud within the galaxy. The ensemble-averaged driving parameter is found to be rather compressive with $b\sim0.5-0.7$, indicating almost time-independent global star formation properties. However, each individual cloud shows a highly fluctuating driving parameter, which would strongly affect the cloud's star formation rate. We find that the mode of turbulence driving can rapidly change within only a few Myr, both from solenoidal to compressive and vice versa. We attribute these changes to cloud collisions and to tidal interactions with clouds or overdensities in the environment. Last, we find no significant differences in the average driving parameter between hydrodynamic and initially strongly magnetised galaxies. However, the magnetic field tends to reduce the overall fluctuation of the driving parameter. The average driving as well as its uncertainty are seen to be in agreement with recent constraints on the turbulence driving mode for solar neighbourhood clouds.
Quantum variance for dihedral Maass forms

We establish an asymptotic formula for the weighted quantum variance of dihedral Maass forms on $\Gamma_0(D) \backslash \mathbb H$ in the large eigenvalue limit, for certain fixed $D$. As predicted in the physics literature, the resulting quadratic form is related to the classical variance of the geodesic flow on $\Gamma_0(D) \backslash \mathbb H$, but also includes factors that are sensitive to underlying arithmetic of the number field $\mathbb Q(\sqrt{D})$.
Scaling Imitation Learning in Minecraft

Imitation learning is a powerful family of techniques for learning sensorimotor coordination in immersive environments. We apply imitation learning to attain state-of-the-art performance on hard exploration problems in the Minecraft environment. We report experiments that highlight the influence of network architecture, loss function, and data augmentation. An early version of our approach reached second place in the MineRL competition at NeurIPS 2019. Here we report stronger results that can be used as a starting point for future competition entries and related research. Our code is available at this https URL.
Identification of Ankle Injury Risk Factors in Professional Soccer Players Through a Preseason Functional Assessment

Background: Etiologically, the risk of an ankle injury depends on extrinsic and intrinsic factors, such as muscle strength asymmetry, decreased flexibility, and decreased proprioception, as well as patient age and history of injuries. Purpose/Hypothesis: The purpose of this study was to identify risk factors present in the preseason assessment that may predispose professional soccer players to ankle injuries. We hypothesized that analysis of these parameters could relate the incidence of injuries to the deficits found during the preseason period, enabling the identification of risk factors to predict the occurrence of injuries. Study Design: Cohort study; Level of evidence, 2. Methods: A total of 89 professional soccer athletes were evaluated in the preseason period; the evaluation included athlete history and anthropometric data collection, an isokinetic ankle evaluation, and functional tests: the Dorsiflexion Lunge Test and Y-Balance Test (YBT). The athletes were monitored during the competitive period, and the incidence of injuries was surveyed. The association of quantitative variables and injury outcomes was analyzed using the Student t test for independent samples, with P < . 05. For the association of categorical variables and injury outcomes, the chi-square test was performed, with P < . 05. Results: A higher incidence of ankle injuries was associated with lower YBT scores in the dominant (P = .04) and nondominant (P = .01) limbs. A higher body mass index was also associated with a higher injury occurrence (P = .01). Conclusion: Functional tests, such as the YBT, are indicated tools for assessing the physical capacities and possible risks of ankle sprains, as they can evaluate the ankle functional capacity in a complex way, identifying athletes more prone to ankle injuries. Athletes’ body mass index should also be taken into account to prevent such injuries.
Estrogen receptor‐α is required for estrogen‐induced μ‐opioid receptor internalization

Endogenous opioid circuits are pivotal for the regulation of sexual receptivity. Treatment of mice with morphine, a preferential μ‐opioid receptor (MOR) agonist, severely attenuates lordosis. Estrogen induces internalization of MOR in cell groups of the limbic‐hypothalamic lordosis‐regulating circuit. Because rapid MOR internalization is mediated by estrogen release of endogenous opioid peptides, internalization has been used as a neurochemical signature of estrogen action in the central nervous system. Together these results indicate that estrogen induces a MOR mediated inhibition of sexual receptivity. To determine which estrogen receptor, estrogen receptor‐α (ERα) or estrogen receptor‐β (ERβ), mediates MOR internalization, ERα knockout (ERαKO), ERβ knockout (ERβKO) and wild‐type (WT) mice were used in the present study. WT, ERαKO and ERβKO mice had similar MOR distributions in the limbic‐hypothalamic lordosis‐regulating circuit. Estrogen treatment internalized MOR in the medial preoptic nucleus of ovariectomized WT and ERβKO, but not ERαKO mice. Treatment of ERαKO mice with the selective endogenous MOR ligand, endomorphin‐1, induced levels of MOR internalization similar to WT mice suggesting that MOR in ERαKO mice could be activated and were probably functional. The results of the present experiments indicate that ERα is required for estrogen‐induced MOR internalization and suggest that ERα can mediate rapid actions of estrogen. © 2002 Wiley‐Liss, Inc.
Disseminating the Foundations of Knowledge Translation and Patient Engagement Science Through the KnowledgeNudge Blog and Twitter Profile: Quantitative Descriptive Evaluation

Background There is a documented need to build capacity for theory- and evidence-informed knowledge translation (KT) and patient engagement (PE) practice in health research. Dissemination of foundational content online coupled with social media promotion may build capacity by increasing awareness, knowledge, and positive attitudes. Objective This retrospective study sought to (1) describe exposure and engagement of the KnowledgeNudge KT and PE dissemination strategy (online blog and Twitter profile) over 2 years and (2) identify and compare characteristics of individual posts with the most and least exposure and reach. Methods Exposure was assessed by blog site views per month and Twitter profile impressions per month. Engagement was assessed by Twitter profile interactions per month. Descriptive statistics were calculated for 6-month blocks and compared using one-way analysis of variance or Student t test. Individual post exposure was assessed by average post views per week. Individual post reach was assessed by average post reads per week. High- and low-profile blog posts with the highest and lowest 10th percentile for exposure and reach were identified. Results A total of 99 posts and 755 tweets were published during the study period. There was a significant increase in exposure (P=.004) and reach (P<.001) during the final 6 months. Seven high-profile and 6 low-profile posts were identified. High-profile posts had a significantly greater average word count than low-profile posts (P=.003). There were no other significant differences between posts. Conclusions The increases in KnowledgeNudge exposure and engagement offer preliminary evidence in support of this dissemination strategy for the practice of KT and PE. Variation in individual post exposure and reach warrants further exploration to tailor content to user needs. Future work will include a prospective evaluation strategy to explore the effect of KnowledgeNudge on awareness, knowledge, attitudes, and behavior.
Effect of Row Spacing on Seed Isoflavone

Soybean isoflavones compounds such as genistein, daidzein, and glycitein have numerous human health benefits including the reduction of risks of cardiovascular diseases, breast and prostate cancers, and menaupose symptoms in women. Understanding the genetic and environmental control of isoflavones accumulation is of great importance for developing new cultivars with high amounts of seed isoflavones. This study was conducted to analyze the effect of row spacing (25 cm vs. 50 cm) on seed isoflavones accumulation using a recombinant inbred line (RIL) population derived from the cross of PI 438489B and “Hamilton” (PIxH, n = 50). The two row spaces generated plant densities of 250,000 plants/ha and 90,000 plants/ha, respectively. Significant differences in soybean seed isoflavones (daidzein, genistein and glycitein) contents have been observed between plants grown in the two different plant densities. The mean daidzein content was 0.03458 μg·g−1 in plants grown in 50 cm row spaces (low plant density), which was significantly higher than its content (0.03019 μg·g−1) in plants grown in 25 cm row spaces (high plant density). Similarly, the mean glycitein content in plants grown in 50 cm row spaces (0.01905 μg·g−1) was significantly higher than its content in plants grown in 25 cm row spaces (0.00498 μg·g−1). Also, the mean genistein content in plants grown in 50 cm row spaces (0.01466 μg·g−1) was higher than its content in plants grown in 25 cm row spaces (0.00831 μg·g−1). These preliminary results are important in guiding farmers and breeders on choosing the best row spaces to grow soybean plants in order to optimize isoflavones contents. Further studies are needed to understand the correlation between seed Corresponding author.
Nurses practice towards palliative care in Shire Endasilasie health facilities, Northern Ethiopia: a cross-sectional study

Introduction The public health strategy of the World Health Organization for palliative care is to increase access to palliative care services by integrating it with the healthcare systems. Therefore, the value of palliative care service provision by nurses who deliver the majority of care to chronical patients is an important issue. The objective of the study is assessing nurses' practice of palliative care. Methods A facility based cross-sectional study was carried out among 278 nurses working in governmental health facilities of Shire Endasilasie town, Tigray region, Ethiopia from February to June 2018. The questionnaire was revised based on the findings of the pre-test. The collected data was checked for its completeness, consistency, and accuracy before analysis. Data were entered and analyzed using SPSS version 22. The final result was reported using text and tables. Results A total of 278 nurses were included in the study and the response rate was 100%. The majority of the participants (71.9%) were females and the mean age of the respondents was 32.08 years (range from 20 to 60). Approximately two-thirds (74.8%) of the respondents had poor knowledge of palliative care practice. Half of the study participants reported emotional support gained as primary psychological support. Commonly used drugs for severe pain were paracetamol or ibuprofen 202 (72.2%) and 47.8% nurses focus on quality patient pain assess. Conclusion The majority of the nurses had a poor practice of palliative care.
First-Time Mothers' Enjoyment of Breastfeeding Correlates with Duration of Breastfeeding, Sense of Coherence, and Parental Couple and Child Relation: A Longitudinal Swedish Cohort Study

Objectives Many women do not reach their own breastfeeding goals regarding duration of breastfeeding. Different factors influence breastfeeding, and to learn more about breastfeeding within a multidimensional and longitudinal perspective, further research is needed. Therefore, the aim of the present study was to investigate diverse factors correlated with first-time mothers' enjoyment of breastfeeding and breastfeeding duration, between childbirth and two years after birth. Methods In a prospective longitudinal cohort study, 324 newly become mothers were followed. The Spearman correlation test was used to investigate factors correlated with the degree to which mothers enjoy breastfeeding and the duration of breastfeeding. The Mann–Whitney test was conducted for comparisons of demographic characteristics between mothers who did or did not breastfeed. Results Among the mothers, 99.2% initiated breastfeeding after birth. Frequencies of breastfeeding were 54.8% at six months, 9.1% at one year, and 1.0% at two years. The degree to which the mother enjoyed breastfeeding was correlated positively with (1) the duration of breastfeeding, (2) more positive feelings for and relation to the child, (3) the partner's perceived relation to the child, (4) a higher sense of coherence, and (5) stronger perceived parental couple's relationship. Longer breastfeeding duration was correlated positively with (1) a higher degree of enjoyment of breastfeeding, (2) more positive relation to the child, and (3) stronger perceived parental couple's relationship. Additionally, breastfeeding during the first two hours after birth, more positive feelings for and relation to the child, and a higher degree of enjoyment of breastfeeding were more frequently reported among breastfeeding mothers, in comparison with not breastfeeding mothers. Conclusion Mothers' subjective experience from breastfeeding, sense of coherence, and couple relationship with partner and relationship with the child are valuable factors in regard to breastfeeding.
Size- and temperature-dependent magnetization of iron nanoclusters

The magnetic behavior of bcc iron nanoclusters, with diameters between 2 and 8 nm, is investigated by means of spin dynamics (SD) simulations coupled to molecular dynamics (MD-SD), using a distance-dependent exchange interaction. Finite-size effects in the total magnetization as well as the influence of the free surface and the surface/core proportion of the nanoclusters are analyzed in detail for a wide temperature range, going beyond the cluster and bulk Curie temperatures. Comparison is made with experimental data and with theoretical models based on the mean-field Ising model adapted to small clusters, and taking into account the influence of low coordinated spins at free surfaces. Our results for the temperature dependence of the average magnetization per atom M(T), including the thermalization of the transnational lattice degrees of freedom, are in very good agreement with available experimental measurements on small Fe nanoclusters. In contrast, significant discrepancies with experiment are observed if the translational degrees of freedom are artificially frozen. The finite-size effects on M(T) are found to be particularly important near the cluster Curie temperature. Simulated magnetization above the Curie temperature scales with cluster size as predicted by models assuming short-range magnetic ordering (SRMO). Analytical approximations to the magnetization as a function of temperature and size are proposed.
Tumor suppressor p53 regulates insulin receptor (INSR) gene expression via direct binding to the INSR promoter

A significant volume of clinical and epidemiological data provides support to the concept that insulin and the insulin receptor (INSR) have an important role in breast cancer. Tumor suppressor p53 is the most frequently mutated molecule in human cancer. The present study was aimed at evaluating the hypothesis that p53 governs the expression and activation of the INSR gene in breast cancer cells. In addition, the study was designed to investigate the mechanism of action of p53 in the context of INSR gene regulation. The availability of MCF7 breast cancer-derived cell lines with specific disruption of either the insulin-like growth factor-1 receptor (IGF1R) or INSR allowed us to address the impact of the IGF1R and INSR pathways on p53 expression. Data indicate that the INSR gene constitutes a target for p53 action. Wild-type p53 stimulated INSR promoter activity in control cells while disruption of endogenous IGF1R or INSR led to inhibition of promoter activity by p53. Mutant p53 strongly stimulated INSR promoter. Furthermore, p53 directly binds to the INSR promoter in cells with a disrupted IGF1R. Combined, our results identified complex functional and physical interactions between p53 and the INSR pathway. The implications of the p53-INSR interplay in breast cancer needs to be further investigated.
Expression levels of circulatory mir-185-5p, vascular endothelial growth factor, and platelet-derived growth factor target genes in endometriosis

Abstract Background Using blood-based biomarkers such as microRNAs (miRNAs) may allow particularly effective and minimally invasive diagnosis and treatment of endometriosis. Objective: We evaluated the differential expression of circulating miRNA-185-5p (miR-185-5p), vascular endothelial growth factor (VEGF), and platelet-derived growth factor (PDGF) target genes between endometriosis and healthy women. Materials and Methods 25 women with a history of endometriosis (grad III-IV) diagnosed by laparoscopy as the case group and 25 women without endometriosis underwent laparoscopy for ovarian cysts or pelvic pain as the control group were enrolled in this case-control study. Blood samples were obtained, and total RNA was used for high-throughput small RNA sequencing, and this was confirmed by means of quantitative real-time polymerase chain reaction (qRT-PCR). Results miRNA expression profiling using non-coding RNA sequencing revealed that one miRNA including miR-185-5p was significantly down-regulated in the case group compared with the controls. The qRT-PCR results showed significant downregulation of the expression level of miR-185-5p (p < 0.01) in the plasma of the case group. Receiver operating characteristic (ROC) curve analysis showed the area of miR-185-5p under the ROC curve for endometriosis diagnosis was 0.919 (p < 0.001). The RT-PCR results demonstrated that there was no significant difference in the expression of VEGF and PDGF mRNA of blood samples in the cases compared to the control group (PDGF, p = 0.09 and VEGF, p = 0.36). Conclusion The low expression of miR-185-5p in the plasma of women with endometriosis could be employed as an important non-invasive biomarker for early detection and screening of endometriosis by blood samples.
Projective symmetry group classifications of quantum spin liquids on the simple cubic, body centered cubic, and face centered cubic lattices

We perform extensive classifications of $\mathbb{Z}_2$ quantum spin liquids on the simple cubic, body centered cubic, and face centered cubic lattices using a spin-rotation invariant fermionic projective symmetry group approach. Taking into account that all three lattices share the same point group $O_h$, we apply an efficient gauge where the classification for the simple cubic lattice can be partially carried over to the other two lattices. We identify hundreds of projective representations for each of the three lattices, however, when constructing short-range mean-field models for the fermionic partons (spinons) these phases collapse to only very few relevant cases. We self-consistently calculate the corresponding mean-field parameters for frustrated Heisenberg models on all three lattices with up to third neighbor spin interactions and discuss the spinon dispersions, ground state energies and dynamical spin structure factors. Our results indicate that phases with non-uniform spinon hopping or pairing amplitudes are energetically favored. An unusual situation is identified for the fcc lattice where the spinon dispersion minimizing the mean-field energy features a network of symmetry protected line-like zero modes in reciprocal space. We further discuss characteristic fingerprints of these phases in the dynamical spin structure factor which may help to identify and distinguish them in future numerical or experimental studies.
The maximum of the periodogram of Hilbert space valued time series.

We are interested to detect periodic signals in Hilbert space valued time series when the length of the period is unknown. A natural test statistic is the maximum Hilbert-Schmidt norm of the periodogram operator over all fundamental frequencies. In this paper we analyze the asymptotic distribution of this test statistic. We consider the case where the noise variables are independent and then generalize our results to functional linear processes. Details for implementing the test are provided for the class of functional autoregressive processes. We illustrate the usefulness of our approach by examining air quality data from Graz, Austria. The accuracy of the asymptotic theory in finite samples is evaluated in a simulation experiment.
Short-Term Bioassay of Chlorophenol Compounds Using Euglena gracilis

Short-term bioassay of chlorophenol compounds such as di- and pentachlorophenol (DCP and PCP) on the movement parameters and photosynthesis activity is tested using Euglena gracilis. Cells were exposed to different concentrations of 2,4-dichlorophenol (2,4-DCP) and pentachlorophenol (PCP) for different incubation times. Results of acute toxicity tests of cell motility showed that Euglena was highly sensitive to PCP after direct exposure in comparison to 2,4-DCP (EC50 were 26.8 mgL−1 and 205.2 mgL−1), respectively. In contrast, 2,4-dichlorophenol shows significant impact on the movement and photosynthesis of the Euglena after longer incubation times (24 hours). Photosynthetic yield of Euglena was suppressed at concentrations ≥1.5 and ≥12 mgL−1 of pentachlorophenol and 2,4-dichlorophenol, respectively. This proves inactivation of photosystem II through inhibition of both electron transport and potential energy of photosynthetic membrane, whereas lower concentrations disturbed Photosystem II making it work ineffectively. Rapid, sensitive, and automatic measurements of several parameters are the main advantages of the studied bioassay.
The influence of environmental variables on soil mite communities (Acari: Mesostigmata) from overgrazed grassland ecosystems – Romania

Abstract In 2013–2014, the soil mite communities from six overgrazed grassland ecosystems located in the Trascău Mountains, Romania, were investigated. Forty-six species were identified, with 645 individuals. Some abiotic factors from soil were measured (soil temperature – T, soil water content – H, soil acidity – pH, carbon content – C, total nitrogen – Nt, and C/Nt ratio). Significant statistical differences were obtained between environmental factors. Using a canonical correspondence analysis of mite species abundance, environmental variables and habitats, strong relationships between investigated factors were established.
Multiple Discrimination against Female Immigrants Wearing Headscarves

Western countries have experienced a large influx of Muslim immigrants, and concomitantly the Muslim headscarf has become the subject of major controversy. Drawing on theories of stigma, social identity, and multiple discrimination/intersectionality, this study examines the effect of wearing this headscarf in the German labor market. The author applies the method of correspondence testing that allows measuring discrimination in a controlled field setting. Findings show that when applying for a job in Germany, women with a Turkish migration background are less likely to be invited for an interview, and the level of discrimination increases substantially if the applicant wears a headscarf. The results suggest that immigrant women who wear a headscarf suffer discrimination based on multiple stigmas related to ethnicity and religion.