Miracle-dz/UniFAR-FTUs huggingface dataset:
Effect of Organic Additives of Okra Cultivated in Unheated Greenhouses on Certain Fruit Characteristics

The experiment conducted during the winter season 2017-2018 in one of the unheated greenhouse in the Research Station of the Faculty of Agriculture collage - All Muthanna University in the south of Iraq inAll Samawah city, in order to study the "Effect of addition cows fertilizer , Water hyacinth compost and spray nanoparticle algae minutes and there impact on some qualities of okra fruits (Hasnawiya cultivar)". The experiment was contain (27) factor treatments and separated in possible combinations among three levels of bovine fertilizer (0, 2, 4) kg/m2and three levels of Water hyacinth compost (0, 2, 4) kg/m2and three concentrations of Organic fertilizer for marine algae nanoparticles extract (0, 0.75, 1.5) ml/L.The statistical design is split-split plot design and the experiment performed twice for three randomized sections and compared to the averages of the coefficients using the least significant difference test at the probability level (0.05). The main results are summarized as follows.1. The addition of bovine fertilizers in the levels of (2, 4) kg/m2the Significant increase in the percentage of total soluble solids for fruits, by an increase of (8.64, 7.08%) and dry matter of fruits by an increase (6.04, 9.78)%. Significant increase in fiber content (0.56 and 0.95%) compared to the comparison treatment, respectively, while the level of 4 kg/m2achieved significant increase in fruit content in vitamin C compared to the comparison treatment and an increase of 5.16%. 2. Levels (2 , 4) kg/m2Significant increase in percentage of total dissolved solids Vitamin C increased by 24.85, 42.23% by 20.02 and 27.00% by the percentage of dry matter and by 9.91 and 12.81%, which led to a significant decrease in fiber percentage by 6.28 and 11.78% Comparative treatment, respectively.3. Spraying with nanoparticle algae minutes in two concentrations (0.75 and 1.5) ml/l significantly increased the percentage of total dissolved solids by (27.13, 53.87)% and in the amount of vitamin C by (24.05 and 50.01%) and in percentage. The dry matter of the fruit increased by 5.90 and 12.36%, which resulted in a significant decrease in the percentage of fiber by 3.74 and 1.85% compared to the comparison treatment, respectively.4. Some bilateral and triple interference showed significant effect in some studied traits.
Equity Premium Prediction with Structural Breaks: A Two-Stage Forecast Combination Approach

This paper introduces a two-stage out-of-sample predictive model averaging approach to forecasting the U.S. market equity premium. In the first stage, we combine the break and stable specifications for each candidate model utilizing schemes such as Mallows weights to account for the presence of structural breaks. Next, we combine all previously averaged models by equal weights to address the issue of model uncertainty. Our empirical results show that the double-averaged model can deliver superior statistical and economic gains relative to not only the historical average but also the simple forecast combination when forecasting the equity premium. Moreover, our approach provides an explicit theory-based linkage between forecast combination and structural breaks which distinguishes this study from other closely related works.
An unrecognized pathway for bacterial invasion of the respiratory tract

Normally, the ciliated, mucus-secreting epithelium is a mechanism competent to protect the lungs against infection by way of the upper respiratory tract. When this epithelium is injured by toxic gas or when the mechanism is otherwise incapacitated, as for example, in aspiration pneumonia, the lumen of the trachea undoubtedly is the pathway traveled by the agent responsible for the pulmonary inflammation. Pneumonia may occur, however, and this is especially true of the lobar type, without demonstrable gross lesion of the upper respiratory tract, and in these circumstances some route other than the above must have been provided. Experimentally, the introduction of pneumococci by intratracheal instillation or by needle puncture of the tracheal wall through the neck, may result in pneumonia. With either of these methods of inoculation, local damage to the mucosa of the trachea occurs. When the needle method is employed, an opportunity is at hand, not only for infection of the submucosa, but of the peritracheal tissue as well. When the organisms are introduced by insufflation into the rabbit, damage to the mucosa of the larynx or upper trachea can hardly be avoided. In either case, an atrium of invasion for the submucosa of the trachea is provided, and histologically infection of the submucosa is evident at the point of inoculation. From here it may be traced throughout the submucosa of the trachea and larger bronchi to the hilum of the lung by way of the peribronchial and periarteriolar structures into the pulmonary tissue. Infection of the lung occurs under these conditions even though cultures from the lower trachea are sterile. An abundant lymphatic system can be demonstrated by the injection of India ink into the submucosa of the trachea.
THE ENHANCED ROLE OF VITAMINS C AND E ON THE TOXIC EFFECTS OF SODIUM NITRATES ON THE LIVER AND TESTIS OF ADULT ALBINO RATS

Background: Acrylamide (ACR) is an industrial pollutant, an exposure to acrylamide via different routes causes selective neurotoxicity. Aim of the Work: This work was performed to study potential neurotoxic effects of acrylamide on the cerebellum in adult albino rats by evaluation of neurobehavioral functional observational tests (gait score, landing hind limb foot splay), histopathological and immunhistochemichal testing of cerebellum. Materials and Methods: This study was carried out on 48 adult male albino rats which divided into 4 equal groups; GroupI (negative control group), Group II (positive control group) GroupIII (low dose acrylamide): Subdivided into two equal subgroups( III a& IIIb ) : each rat was gavaged orally with daily dose of 8.5mg/kg acrylamide for 4 & 8 weeks respectively. Group IV (high dose acrylamide): Subdivided into two equal subgroups( IV a& IV b ) : each rat was gavaged orally with daily dose of 17 mg/kg acrylamide for 4 & 8 weeks respectively. Results: There was a significant increase in both mean rank and mean values of gait scores and landing hind limb foot splay of both treated groups as compared to those of control groups. There was a strong positive correlation between foot splay and gait score, Microscopic examination of H&E stained of cerebellum of both treated groups showed loss of purkinjie cells, ACR affections were dose and time dependent . Silver stained cerebellar sections of rats received low dose for 4 weeks showed loss of some Purkinje cells, other rats received low dose for 8 weeks or high dose showed loss of most Purkinjie cells and the fibers of the white matter were seen with progressive fragmentation. Immunolocalization of Glial Fibrillary Acidic Protein (GFAP) in the cerebellum of treated groups showed progressive distribution of GFAP-positive astrocytes which was dose and time dependent. There was a strong positive correlation between area percentage and landing hind limb foot splay, a moderate positive correlation between area percentage and gait score. Conclusion: Acrylamide has a neurotoxic effect clarified by impairment of gait score and increase in landing hind limb foot splay. The abnormal neurobehavioral functional observational tests were associated to cerebellar histopathological changes in the form of selective loss of purkinjie cell, axonapathy and gliosis. Recommendation: it is recommended to increase public awareness about the health impact of exposure to acrylamide.
An application of Altman Z-score model to analyze the bankruptcy risk: cases of multidisciplinary enterprises in Vietnam

This study applied Altman Z-score model to assess the bankruptcy risk of a set of multidisciplinary enterprises of various types, mainly small and medium enterprises, with data taken from official financial reports of 180 enterprises in Soc Trang province. The binary logistic regression was employed to assess the impact of non-financial and financial factors on the bankruptcy risk of enterprises. The research findings showed that both the non-financial factors such as business area, types and size of the business, the educational level of managers and executors and other characteristics, and the financial factors (indicators) such as earnings before tax, net profit/equity ratio, earnings before interest and tax/total assets ratio, equity/total debt ratio, affect the bankruptcy risk of enterprises. Predicting the bankruptcy risk and measuring its determinants play an important role not only as an effective managing tool of the business, but also as evidence for policymakers to support the sustainable development of business.
Histomorphometry of small intestine in post-hatch Uttara fowl.

Uttara breed of fowl has evolved through natural selection in indigenous agro-ecological conditions and is well adapted to the local environment of Kumaon region of Uttarakhand state, situated at the Himalayan foothills. It is a docile bird to keep and provides an important animal origin food source of high nutritive value to the local inhabitants. The present study was planned to investigate the post hatch development of the absorptive structure and relative thickness of tunics in different segments of the small intestine. Histomorphometry is one of the basic and valuable techniques in histological studies. The present work was designed and carried out to elucidate the histomorphometrical features of the small intestine of Uttara fowl. Analysing the results, it was observed that the mucosa of the intestinal villi was lined by simple columnar epithelium. The entire length of intestinal mucosa was studded with villi of variable shape and size. The villi were longest (1675.0 μm) in duodenum. Overall mean thickness of the tunica mucosa was maximum (2008.3 μm) and minimum (789.5 μm) in duodenum and ileum respectively. However, thickness of the tunica muscularis was maximum (341.6 μm) in ileum which increased from duodenum to ileum with advancing age. The major conclusion was the observation that duodenum is the principal site of nutrient absorption in Uttara fowl breed.
Do External Stakeholder Pressures Influence Customer Service and Complaints Handling Practices in the Australian Internet Service Provider Industry

Poor customer service (CS) and complaints handling (CH) performance of the Australian Internet Service Provider (ISP) industry has been the subject of intense scrutiny over the past few years. Internet industry stakeholders such as the ombudsman, consumer association, regulator and government authorities have considered tighter regulation as a response to address the industry’s poor CS track record. This paper explores the role of external stakeholder pressures on the very large ISP (vlISP) industry that resulted in significant revisions to the CS/CH sections of Telecommunication Consumer Protection (TCP) Code. Qualitative research using eleven in-depth interviews with senior vlISP industry executives was conducted. Data analysis found that three key pressures (regulatory, customer, competition) influenced the revisions to the TCP code. Very few studies in the Australian context examine personal viewpoints of vlISP industry stakeholders to understand how and why vlISPs respond to such pressures. This is the first study that examines such viewpoints using an institutional theory lens. The study findings are: encourage vlISPs to collaborate with relevant stakeholders to manage expectations regarding CS/CH performance; provide valuable information for regulatory agencies, the consumer association and the complaints authority to develop an understanding of what pressures drive the changes required to enhance service improvements in areas where vlISPs under-perform; and assist external stakeholders to understand the types of pressures to which vlISP managers respond. The study findings will inform future quantitative studies to examine the influence of such pressures on the actual CS/CH performance of vlISPs.
Autologous Microfragmented Adipose Tissue Reduces the Catabolic and Fibrosis Response in an In Vitro Model of Tendon Cell Inflammation

Background Mesenchymal stem cells (MSCs) emerged as a promising therapy for tendon pathologies. Microfragmented adipose tissue (μFAT) represents a convenient autologous product for the application of MSC-based therapies in the clinical setting. In the present study, the ability of μFAT to counteract inflammatory processes induced by IL-1β on human tendon cells (TCs) was evaluated. Methods Cell viability and proliferation were evaluated after 48 hours of transwell coculture of TCs and autologous μFAT in the presence or absence of IL-1β. Gene expression of scleraxis, collagen type I and type III, metalloproteinases-1 and -3, and cyclooxygenase-2 was evaluated by real-time RT-PCR. The content of VEGF, IL-1Ra, TNFα, and IL-6 was evaluated by ELISA. Results IL-1β-treated TCs showed augmented collagen type III, metalloproteases, and cyclooxygenase-2 expression. μFAT was able to reduce the expression of collagen type III and metalloproteases-1 in a significant manner, and at the same time, it enhanced the production of VEGF, IL-1Ra, and IL-6. Conclusions In this in vitro model of tendon cell inflammation, the paracrine action of μFAT, exerted by anti-inflammatory molecules and growth factors, was able to inhibit the expression of fibrosis and catabolic markers. Then, these results suggest that the application of μFAT may represent an effective conservative or adjuvant therapy for the treatment of tendon disorders.
Effect of Ginkgo biloba Leaf Extract (EGb 761) on Changes in Haematological Parameters and Erythrocyte Osmotic Fragility in Hypotonic and Chlorpyrifos Exposed Rats

BACKGROUND: Canine low-dose sepsis model provides a reliable setting to study innovative drugs. Lipopolysaccharides (LPS), a major constituent of bacterial outer membrane, have been demonstrated to play a critical role in the initiation of pathogenesis. Lipopolysaccharide-induced sepsis has been extensively studied in laboratory animals; but its importance has mainly remained unknown in dogs. OBJECTIVES: The aim of the present survey was to examine the effectiveness of quercetin, along with hydrocortisone on clinical and hematological alterations, and organ failure (liver and heart) in low-dose lipopolysaccharide-induced canine sepsis model. METHODS: For this purpose, fifteen clinically healthy mixed dogs were randomly divided into three equal groups. Lipopolysaccharide (0.1 μg/kg, IV) was injected to dogs in group A (control). Group B was similar to group A, but quercetin bolus (2 mg/kg, IV, once) was injected 40 minutes after LPS injection. Group C was similar to group B; however, hydrocortisone bolus (2 mg/kg, IV, once) was administered instead of quercetin. Serum levels of glucose, total protein, albumin, alanine aminotransferase (ALT), aspartate aminotransferase (AST), alkaline phosphatase (ALP), creatine kinase isoenzyme muscle/brain (CK-MB), lactate dehydrogenase (LDH) and cardiac troponin I (cTn-I) concentration were measured by commercial kits. RESULTS: In control group, red blood cells (RBCs), hemoglobin (Hb), and hematocrit (HCT) significantly decreased and serum activities of AST, ALP, LDH, CK-MB, and plasma cTn-I significantly increased (P<0.05). RBCs, Hb, and HCT significantly increased in quercetin group, compared with hydrocortisone and control groups (P<0.05). Quercetin group significantly decreased LDH, CK-MB, and cTn-I compared with hydrocortisone and control groups (P<0.05). Quercetin significantly decreased AST in comparison to control group and ALP in comparison to hydrocortisone group, also (P<0.05). CONCLUSIONS: These results suggest that quercetin protects RBCs in the early stages of sepsis and decreases organs dysfunction (heart and liver), therefore it has a positive influence on sepsis and may be more effective than routine corticosteroid (hydrocortisone) therapy.
Effect of Enamel Resin-Removal Methods on Tensile Bond Strength of Rebonded New Brackets

Aims: The objective of this study is to determine (1) the effect of different resin-removal methods on tensile bond strength (TBS) of rebonded new brackets (2) compare various methods of enamel resinremoval to define the best method that produces adequate bond strength (3) to compare the bond strength of newly bonded enamel (virgin enamel) with previously bonded enamel after resin removal from the enamel surface with different methods. Materials and Methods: Seventy human premolars were bonded with stainless steel new brackets, then the teeth were randomly assigned in to 7 groups, each group of 10 teeth. Group1 (control group) where TBS at the first debonding was evaluated (initial bond). Group2 brackets were debonded by bracket removal plier and the remnant adhesive removed by high-speed tungsten carbide bur (TCB) and rebonded with brackets as in initial bond, then the TBS were tested. Group3 as with group2 except that the remaining resin were removed by low-speed TCB . Group 4 as with group2 except that the remaining resin were removed by Diamond carbide Disk . Group 5 as with group2 except that the remaining resin were removed by a microetcher, Group 6 as with group 2 except that the remaining resin were removed manually by composite removing pliers, Group 7 as with group6 except that rebonding bracket without cleaning enamel with rubber cup and pumice. Results: All rotary instrument groups (G2, G3 and G4) showed significant increase in the TBS in comparing with the other groups (G1, G5, G6 and G7) also there were significant decrease in the TBS of the manually removal of adhesive remnant groups in comparing with control group, while there were no significant differences between microetcher group and control group with greater mean value for control group. Conclusions: The outcomes of this study showed that the use of the rotary instrument in the removal of adhesive remnant gives the highest tensile bond strength in compared with the other methods used in this study .
Desempeño no clínico y aceptabilidad de un estimulador respiratorio portátil para reanimación neonatal básica, evaluado en personal de salud

Introduction: Neonatal resuscitation demands equipment for respiratory support not always available in rural areas. Innovative devices are required, and rapid prototyping allows to generate them using three-dimensional (3D) designs and printers. Objective: To evaluate the non-clinical performance and the acceptability by health personnel of a neonatal respiratory device produced by rapid prototyping. Methods: Observational study, descriptive, of proof of concept developed in two steps. Step 1: Manufacture of the device with rapid prototyping in three-dimensional (3D) scanners and printers. Step 2: Demonstration of the invention during training programs in neonatal resuscitation for health personnel in three regions of Peru (Tarapoto, Huánuco and Ayacucho). In both steps, we evaluated the performance of the device connected to a gas flow analyser. A survey was administered to the health workers of Tarapoto and Ayacucho to know their acceptability. Results: The developed prototype is T-shaped with two side bellows that, when pressed with one hand, project air through the centre towards a facial adapter. The use of the prototype in the laboratory generated an average air flow of 4.8 Lt /min (SD ± 1.7) and an average pressure of 5.9 cmH2O (SD ± 1.4). This device was considered to be “very simple to use” in an acceptability survey involving 39 nurses and 11 doctors in remote areas of the capital of Peru. Conclusions: The evaluated prototype is acceptable by the staff and has a performance capable of generating spontaneous breathing at birth.
Effect of Particle Size on the Compressibility and Sintering of Titanium Powders

In this research, the effects of the powder particle size on the compaction and sintering of Hydride‌–Dehydride titanium powders are investigated. Commercially pure titanium powders with three different size ranges were utilized. Compaction was accomplished under applied pressures of 200 to 650 MPa. Sintering was carried out at 1100 to 1400 oC temperatures. The compressibility behavior of the differently-sized powders was studied by measuring the density of the green compacts. The microstructure of produced compacts was studied using scanning electron microscopy. Results showed that the small powders have the least compressibility. The compressibility data was analyzed and studied by common compaction equations. The modified Heckel equation showed the best correspondence. In addition, measuring the density of sintered compacts showed that the small powders had the highest sinterability. The highest amount of sintered density (98% theoretical) was attained for the small powder compacted under 650 MPa and sintered at 1400 oC. However, the sintering temperature of 1200 oC was recognized as the most appropriate temperature for the middle and large-sized titanium powders. The results of hardness tests showed that the appropriate mechanical properties could be attained for commercially pure titanium powder compacts by vacuum sintering accomplished at the optimum sintering circumstances.
FDI and regional income disparity in the Czech republic

The aim of this paper is to evaluate the impact of FDI along with domestic physical investment and human capital on the regional income, and their role in the regional income convergence within the Czech economy over the periods from 1998-99 to 2013-14. The paper considers 14 regions of the Czech Republic and uses panel fixed effect regression and dynamic panel growth framework for the empirical analysis. The result finds that the role of physical capital formation and FDI along with the human capital are crucial for the regional disparity in income in the Czech Republic. There is also evidence of the convergence of per capita income at the speed of 7.8 per cent among the regions by conditioning physical investment and human capital along with FDI. This paper suggests that regional disparity in income can be reduced by the equitable allocation of investment and FDI, and equal development of human capital.
JNK/AP1 Pathway Regulates MYC Expression and BCR Signaling through Ig Enhancers in Burkitt Lymphoma Cells

In Burkitt lymphoma (BL), a chromosomal translocation by which the MYC gene is fused to an immunoglobulin (Ig) gene locus is frequently found. The translocated MYC gene is overexpressed, which is the major driver of BL tumorigenesis. Studies have shown that Ig enhancers are essential for MYC overexpression, but the involved mechanisms are not fully understood. In addition, the survival of BL cells relies on B-cell receptor (BCR) signaling, which is determined by the levels of Ig molecules expressed on the cell surface. However, whether MYC has any impact on Ig expression and its functional relevance in BL has not been investigated. Herein, we show that MYC upregulates Ig kappa (Igκ) expression in BL cells through two Igκ enhancers, the intronic enhancer (Ei) and the 3ʹ enhancer (E3ʹ). Mechanistically, by activating the JNK pathway, MYC induces the phosphorylation of c-Fos/c-Jun and their recruitment to AP1 binding sites in the Igκ enhancers, leading to the activation of the enhancers and subsequent Igκ upregulation. The AP1-mediated activation of the Igκ enhancers is also required for the expression of the translocated MYC gene, indicating positive feedback for the MYC overexpression in BL cells. Importantly, interrupting the JNK pathway inhibits both Igκ and MYC gene expression and suppresses BL cell proliferation. Our study not only reveals a novel mechanism underlying MYC overexpression in BL but also suggests that targeting the JNK pathway may provide a unique strategy to suppress BL tumorigenesis.