Miracle-dz/UniFAR-FTUs huggingface dataset:
A Weibull Distribution: Flow and Heat Transfer of Nanofluids Containing Carbon Nanotubes with Radiation and Velocity Slip Effects

In this study, the Tiwari and Das model is numerically studied, in case of a moving plate containing both single-walled and multiwalled carbon nanotubes (SWCNTs and MWCNTs, respectively), in the presence of thermal radiation and the slip effect. Employing the similarity transformation, a set of 2nd-order partial differential equations (which are used to model the flow and heat transfer) are solved numerically using the boundary value problem with 4th-order accuracy (BVP4C) method. The effects of related parameters, such as the volume fraction of nanoparticles, moving, slip, and radiation parameter on the heat transfer performance are analysed and discussed. Results indicate that a unique solution was placed when the plate travels in assisting flow conditions. Additionally, as the nanoparticle volume fraction (φ) rises at φ = 0.2, the skin friction and heat transfer rate decrease. It is also observed that when the slip parameter (β) increases at β = 0.4, the skin friction decreases, whereas the heat transfer rate increases. Meanwhile, the heat transfer rate decreases when the thermal radiation (NR) increases to 0.7. Moreover, it is found that the SWCNTs are more efficient when the skin friction coefficient and the Nusselt number are considered. It is found that the Weibull distribution is more suitable in fitting the skin friction data.
Status of available major nutrients in soils of Gandhi nagar district of Gujarat

A study was undertaken to outline the status of obtainable major nutrients and chemical properties of soils of Gandhinagar district of Gujarat. Total 160 representative surface soil samples (forty soil samples from each taluka) were collected from farmers’ fields during April, 2016 using multistage stratified random sampling. The collected soil samples were analyzed for available major (N, P, K and S) and chemical properties viz., electrical conductivity (EC), soil reaction (pH) and organic carbon. Soils of Gandhinagar district are mildly to moderately alkaline in reaction (pH 7.94) with low soluble salt content (EC 0.52 dS/m). The organic carbon status of soils of Gandhinagar district was low (0.38 %). The available nitrogen, phosphorus, potassium and sulphur content in these soils ranged from 78.6 to 376.3, 18.61 to 69.57, 114.24 to 645.33 kg/ha and 6.74 to 36.06 mg kg-1 with a mean value of 231.8, 41.06, 306 kg/ha and 18.97 mg kg-1, respectively. Out of 160 soil samples, 79.38 per cent were found to be low in available nitrogen status, 71.88 per cent were found to be medium in available phosphorus status, 50 per cent were found to be high in available potassium status and 48.75per cent were found to be high in available sulphur status.
The Antioxidative Action of ZTP by Increasing Nrf2/ARE Signal Pathway

So far, more than 25,000 brain diseases have been shown to be related to oxidative stress. Excessive free radicals and reactive oxygen species (ROS) can attack cells resulting in dysfunctional proteins, lipids, and nucleic acid, finally leading to imbalance of energy metabolism, cell death, gene mutation, and immune reaction. Therefore oxidative stress plays an important role in neuronal diseases. As a traditional Chinese medicine, Zhengtian Pill (ZTP) was reported to have the ability to reduce the blood viscosity of migraine model rats, with increased beta-endorphin, serotonin, adrenaline, and dopamine in brain tissue. Moreover ZTP can effectively accelerate blood circulation and attenuate blood coagulation. However, the molecular mechanisms of ZPT are still unclear. Through the behavioral test we found that ZTP can significantly improve depression-like behavior induced by LPS when rat was treated with ZTP (L 0.17 g/kg, M 0.34 g/kg, and H 0.7 g/kg) intraperitoneal injection once a day for 30 consecutive days. And ZTP can resist oxidative stress (>72 h) for a longer time. And ZTP can promote the levels of ATP and SOD and reduce the levels of ROS and MDA in the brain. At the same time, ZTP can have antioxidant stress through increasing the expression level of Nrf2/HO-1/P38. These results show that ZTP may be a potential antioxidant stress drug for variety of diseases associated with oxidative stress injury.
High-Assurance Cryptography in the Spectre Era

High-assurance cryptography leverages methods from program verification and cryptography engineering to deliver efficient cryptographic software with machine-checked proofs of memory safety, functional correctness, provable security, and absence of timing leaks. Traditionally, these guarantees are established under a sequential execution semantics. However, this semantics is not aligned with the behavior of modern processors that make use of speculative execution to improve performance. This mismatch, combined with the high-profile Spectre-style attacks that exploit speculative execution, naturally casts doubts on the robustness of high-assurance cryptography guarantees. In this paper, we dispel these doubts by showing that the benefits of high-assurance cryptography extend to speculative execution, costing only a modest performance overhead. We build atop the Jasmin verification framework an end-to-end approach for proving properties of cryptographic software under speculative execution, and validate our approach experimentally with efficient, functionally correct assembly implementations of ChaCha20 and Poly1305, which are secure against both traditional timing and speculative execution attacks.
STATISTICS OF HECKE EIGENVALUES FOR GL(n)

A two-dimensional central limit theorem for the eigenvaules of GL(n) Hecke-Maass cusp forms is newly derived. The covariance matrix is diagonal and hence verifies the statistical independence between the real and imaginary parts of the eigenvalues. We also prove a central limit theorem for the number of weighted eigenvalues in a compact region of the complex plane, and evaluate some moments of eigenvalues for the Hecke operator Tp which reveal interesting interferences.
Studies on food consumption indices as influenced by BM NPV infection

Silkworm Bombyx mori L. is highly susceptibility to grasserie disease caused by Bombyx mori nuclear polyhedrosis virus (BmNPV). The amount of food ingested due to BmNPV infection during fourth instar was significantly maximum in CSR2 (225.56 g/100 larvae) followed by PM × CSR2 (219.33 g/100 larvae, while significantly lowest food consumption was recorded in BL43 (191.58 g/100 larvae) followed by MH1 (194.95 g/100 larvae). Among the PIBs concentrations, the amount of food ingested was significantly maximum in 10 PIBs (207.25 g/100 larvae) which was on par with 10 PIBs (206.74 g/100 larvae) compared to control (214.71 g/100 larvae). whereas, the amount of food ingested during fifth instar, the food ingested was significantly maximum in CSR2 (1057.36 g/100 larvae), which was on par with that of PM × CSR2 (1050.12 g/100 larvae). Among the PIBs concentrations, the food ingested was significantly maximum at 10 (1252.29 g/100 larvae) followed by 10 PIBs (1158.12 g/100 larvae) compared to the control (651.75 g/100 larvae). Similarly, The food digestion was significantly maximum in CSR2 (180.03 g/100 larvae), which was on par with PM × CSR2 (179.05 g/100 larvae) and MH1 × CSR2 (179.05 g/100 larvae). It was significantly minimum in BL43 (160.35 g/100 larvae). The food digestion was maximum in CSR2 × CSR4 (838.85 g/100 larvae) followed by PM × CSR2 (834.08g / 100 larvae) and MH1 × CSR2 (834.44 g/100 larvae). It was minimum in MH1 (797.25 g / 100 larvae) followed by BL43 (798.33 g/100 larvae).
Diabetic Retinopathy Severity in patients with Diabetic Foot Syndrome

1 Assistant Professor, Department of Ophthalmology, Govt. Medical College, Doda, J&K 2 Resident, Department of Ophthalmology, Govt. Medical College, Doda, J&K *Corresponding Author Dr Swati Sharma Abstract Background: Diabetes is a common comorbidity in today’s world with many complications. Diabetic retinopathy and diabetic foot ulcer are frequently encountered complications of diabetes and account for a large number of hospital visits. Objective: The purpose of conducting this study is to access the retinopathy status of patients with diabetic foot syndrome and to evaluate any relation between their severities. Methods: Patients with diabetic foot syndrome visiting GMC Doda over a period of one and half month were subjected to ophthalmoscopic examination for documentation of their diabetic retinopathy severity. Results: Twenty five patients were enrolled in the study, all of whom had type 2 DM of at least 5 years duration. All patients had some degree of diabetic neuropathy and associated diabetic foot syndrome. No correlation was found between the severity of diabetic retinopathy and that of diabetic foot syndrome (p value = .56). Conclusion: Our study did not find any correlation between the severity of diabetic retinopathy and that of diabetic foot syndrome.
Reliability Assessment Of Cisco Nexus 9500 Modular Switch N9K-XP636PQ In Data Centre Switching System

: A relative reliability study assessment performed on seven emerging data centre switching system (DCSS) with Switching Cloud Scale Technology in Nigeria is presented in this paper. The Reliability of Cisco Nexus 9000 Series Chassis Switches used in Tier III and Tier IV Green Data Centre in Lagos, Nigeria is the comparison of the Mean Time before Failure (MTBF) and Mean Time to Repair (MTTR) with respect to the base failure rate. We illustrate and focus our analysis on the theoretical convergence properties of MTTR, MTBF and Base failure rate result with the probabilistic (average case) studies through analytical approaches (stochastic processes). The Result reveals a higher key performance Indicators for the reliability of the system used in Rack Centre as compared to the other operating data centres in Lagos Nigeria where this assessment was performed. The time the Cisco Nexus 9500 Modular Switch N9K-XP636PQ Line cards in the data centre switching system is expected to operate before failure (MTBF) in Rack Centre Lagos is 3 years as against 8 years in other operating data centres in Lagos Nigeria. The base failure rate ratio 30: 80 shows that the system fails eight times earlier in these emerging data centres as compared to three times later in Rack Centre environment.
patel, saurin and sarkissian, sergei

The literature has conflicting reports regarding the impact of group decision making on performance. We first observe that in mutual fund studies this results from large discrepancies in reported managerial structures between CRSP and Morningstar databases reaching on average 20% per year. Then we show that with more superior Morningstar data team-managed funds exhibit higher risk-adjusted returns than single-managed funds. The performance spread is present across all fund categories, except aggressive funds, and is robust to the inclusion of fundand manager-level controls. Across various managerial structures, the largest team-induced gains are reached among funds managed by three individuals. Furthermore, teams significantly improve fund performance when funds are located in financial centers, reflecting larger networking potential and/or better skills of people who reside in larger cities. This improvement is achieved in teams more homogeneous in age and education. In spite of higher returns however, team-managed funds are not riskier than single-managed funds in terms of market exposure or idiosyncratic volatility. Finally, team-managed funds trade less aggressively and are able to generate extra inflows for their funds. Thus, collective decision making is beneficial, but its scale depends on team size and diversity as well as its geographic location. JEL classifications: G23; J24
BASC CARM1 is required for proper control of proliferation and differentiation of pulmonary epithelial

methyltransferase I (CARM1; PRMT4) regulates gene expression by multiple mechanisms including methylation of histones and coactivation of steroid receptor transcription. Mice lacking CARM1 are small, fail to breathe and die shortly after birth, demonstrating the crucial role of CARM1 in development. In adults, CARM1 is overexpressed in human grade-III breast tumors and prostate adenocarcinomas, and knockdown of CARM1 inhibits proliferation of breast and prostate cancer cell lines. Based on these observations, we hypothesized that loss of CARM1 in mouse embryos would inhibit pulmonary cell proliferation, resulting in respiratory distress. By contrast, we report here that loss of CARM1 results in hyperproliferation of pulmonary epithelial cells during embryonic development. The lungs of newborn mice lacking CARM1 have substantially reduced airspace compared with their wild-type littermates. In the absence of CARM1, alveolar type II cells show increased proliferation. Electron microscopic analyses demonstrate that lungs from mice lacking CARM1 have immature alveolar type II cells and an absence of alveolar type I cells. Gene expression analysis reveals a dysregulation of cell cycle genes and markers of differentiation in the Carm1 knockout lung. Furthermore, there is an overlap in gene expression in the Carm1 knockout and the glucocorticoid receptor knockout lung, suggesting that hyperproliferation and lack of maturation of the alveolar cells are at least in part caused by attenuation of glucocorticoid-mediated signaling. These results demonstrate for the first time that CARM1 inhibits pulmonary cell proliferation and is required for proper differentiation of alveolar purchased BEAS-2B cells transfected using DharmaFECT transfection reagents (Dharmacon) according to the manufacturer’s protocol. At 48 hours post-transfection, cells were incubated with RPMI containing 10% FBS in the presence of 0.1% ethanol (control) or 500 nM dexamethasone (Sigma-Aldrich) for an additional 72 hours. RNA isolation and qRT-PCR analysis were performed as described above.
Interagierende Trägheitsmoden in einem differenziell rotierenden Kugelspaltexperiment Interacting inertial modes in a differentially rotating spherical gap flow experi- ment

Inertial modes are Coriolis-restored linear wave modes that arise in rapidly rotating fluids. Recent experimental works showed that inertial modes exist in differentially rotating spherical gap flows [1,2]. It is an open issue why only a few modes develop and how they get enhanced. We present a study of inertial modes in the Cottbus' spherical gap apparatus (Fig. 1), where the inner sphere is sloweror counter-rotating with respect to the outer shell. The Rossby number out out in Ro      / ) ( , with in  and out  the inner and outer sphere rotation rate, characterizes the flow. We use a simple Particle-Image-Velocimetry (PIV) system in the rotating frame of the outer shell to visualize the flow in the gap [3]. Since most of the previous spherical shell experiments are without optical access, our method gives us new qualitative and quantitative insights into the flow between concentric spheres. With that we are able to show for the first time quantitative horizontal velocity fields of the inertial modes in a differentially rotating spherical gap experiment. We compare the uniquely identified modes with the literature [1,2] and, moreover, we confirm that the experimentally obtained modes are indeed similar to their analytic full-sphere counterparts derived by Zhang et al. 2001 [4].
Recurrent hoarseness in a 12-year-old female patient with pachyonychia congenita type 1: case report and literature review

We report a phoniatric evaluation of a 12-year-old female with pachyonychia congenita type 1 (JadassohnLewandowsky syndrome) and recurrent hoarseness. Pachyonychia congenita (PC) is an ultra rare genetic disorder of keratinisation that predominantly affects not only the nails, skin, hair, but also oral mucosae and larynx. Hoarseness is reported in 16% of patients with this disease and is attributed to laryngeal leukoplakia. However, assessment of this symptom in most PC cases is subjective and a detailed phoniatric assessment of patients with PC and hoarseness has not been described in the literature so far.
Running Head: Top Talent in Teams The Too-Much-Talent Effect: Team Interdependence Determines When More Talent Is Too Much Versus Not Enough

Five studies examined the relationship between talent and team performance. Two survey studies found that people believe there is a linear and nearly monotonic relationship between talent and performance: participants expected that more talent increases performance and that this relationship would never turn negative. However, building off research on status conflicts, we predicted that talent facilitates performance.but only up to a point, after which the benefits of more talent will decrease and eventually turn negative as intra-team coordination suffers. We also predicted that the level of task interdependence would be a key determinant of when more talent would be detrimental versus beneficial. Three archival studies revealed that the too-muchtalent effect only emerged when in tasks where team members were interdependent (football and basketball) but not independent (baseball). Our basketball analysis established the mediating role of team coordination. When teams need to come together, more talent can tear them apart.
Effect of green tea (Camellia sinensis) extract feeding on serum biochemical indices (Cholesterol, HDL, Lipid peroxide and LDL) of hamster under different dietary treatments

Seventy two weaned Syrian hamsters of either sex were randomly assigned to six treatments in single cages (290mm X 220mm X 140mm) in a closed room where the temperature and relative humidity was maintained 24±50C and 60±15%, respectively during the trial of 56 days. The experiment consisted of six treatments. The concentrate mixture of all the groups was formulated using wheat, fish meal, ground nut cake, mineral mixture and common salt. Feed provided to each treatment was same. Treatment T1, T3 and T5were provided with pure water only. While treatment group T2, T4 and T6were provided with green tea extract only. Green tea extract was prepared by dipping green tea bag (1.3g) in 130 ml boiling water so that effectively it formed 1 percent w/v solution. Hemato-biochemical parameters in terms of Cholesterol, HDL, LDL, Lipid Peroxide improved significantly in the treatment groups in which GTE was provided (T2, T4 and T6). It is inferred from the results that T2, T4 and T6 treatment groups (in which green tea was provided) showed better growth profile in comparison to the rest of the treatment groups (T1, T3 and T5). It is also inferred that rice Huskas a bedding material proved to be the best as compared to saw dust and sand.
Challenges Facing Local Contractors Working with Chinese Contractors in Addis Ababa Building Projects

Building construction projects particularly represents one of the largest sectors of the construction industry. Currently, the rise in construction of high rising buildings are observed in Addis Ababa, the capital city of Ethiopia. The number and size of building construction projects that are being constructed in the city are increasing through time and most of these projects were being carried out by Chinese contractors. Local contractors are also involved in those projects via a subcontracting strategy. However, it is not easy for local contractors to succeed by working with their foreign counterparts who have massive international experience and capacity. The aim of this study was assessing and identifying the challenging factors affecting local contractors’ performance in Chinese building projects in Addis Ababa. In order to achieve the objectives of this study, both quantitative and qualitative research approach were used with primary and secondary source of data. This study employed three types of data collection techniques such as a questionnaire surveys, interviews and observations. The target population for this study are local contractors and consultants involved in building projects that are carried out by Chinese contractors. In this study the researcher used Census/Parametric method of survey. That mean all target population of this study are included in this investigation, based on the consent and willingness of the participants. The Relative Importance Index (RII) was used as an instrument for analyzing data collected through questionnaire in tabular form by using Likert’s scale of five ordinal measures. Based on the analysis, it was found that the most challenging factors affecting local contractors’ performance in Chinese building projects were financial constraints, information exchange problems, cultural differences, unfamiliarity with Chinese work methodology and project complexity with a RII value of 0.84, 0.81, 0.77, 0.73 and 0.71 respectively. This study also identified and discussed the major cause and impact of those challenges and proposed measures to minimize their effect on the local performance in the upcoming projects through interviews from respondents and analyzed by using content analysis.
TBC1D15/RAB7-regulated mitochondria-lysosome interaction confers cardioprotection against acute myocardial infarction-induced cardiac injury

Rationale: Ischemic heart disease remains a primary threat to human health, while its precise etiopathogenesis is still unclear. TBC domain family member 15 (TBC1D15) is a RAB7 GTPase-activating protein participating in the regulation of mitochondrial dynamics. This study was designed to explore the role of TBC1D15 in acute myocardial infarction (MI)-induced cardiac injury and the possible mechanism(s) involved. Methods: Mitochondria-lysosome interaction was evaluated using transmission electron microscopy and live cell time-lapse imaging. Mitophagy flux was measured by fluorescence and western blotting. Adult mice were transfected with adenoviral TBC1D15 through intra-myocardium injection prior to a 3-day MI procedure. Cardiac morphology and function were evaluated at the levels of whole-heart, cardiomyocytes, intracellular organelles and cell signaling transduction. Results: Our results revealed downregulated level of TBC1D15, reduced systolic function, overt infarct area and myocardial interstitial fibrosis, elevated cardiomyocyte apoptosis and mitochondrial damage 3 days after MI. Overexpression of TBC1D15 restored cardiac systolic function, alleviated infarct area and myocardial interstitial fibrosis, reduced cardiomyocyte apoptosis and mitochondrial damage although TBC1D15 itself did not exert any myocardial effect in the absence of MI. Further examination revealed that 3-day MI-induced accumulation of damaged mitochondria was associated with blockade of mitochondrial clearance because of enlarged defective lysosomes and subsequent interrupted mitophagy flux, which were attenuated by TBC1D15 overexpression. Mechanistic studies showed that 3-day MI provoked abnormal mitochondria-lysosome contacts, leading to lysosomal enlargement and subsequently disabled lysosomal clearance of damaged mitochondria. TBC1D15 loosened the abnormal mitochondria-lysosome contacts through both the Fis1 binding and the RAB7 GAPase-activating domain of TBC1D15, as TBC1D15-dependent beneficial responses were reversed by interference with either of these two domains both in vitro and in vivo. Conclusions: Our findings indicated a pivotal role of TBC1D15 in acute MI-induced cardiac anomalies through Fis1/RAB7 regulated mitochondria-lysosome contacts and subsequent lysosome-dependent mitophagy flux activation, which may provide a new target in the clinical treatment of acute MI.