Miracle-dz/UniFAR-FTUs huggingface dataset:
Pediatric health care use during the COVID‐19 pandemic: Lessons learned from the initial 2020 wave

During the height of the coronavirus disease‐2019 (COVID‐19) pandemic, there was a decline and shift in pediatric medical care use. We aimed to assess changes to pediatric medical use and perceptions/barriers that influenced caregivers’ decision‐making during the New York State mandated lockdown from March 22 to June 8, 2020, in a population that opted to use the pediatric emergency department (PED) during this period. This study was conducted in New York City (NYC), one of the epicenters at the height of the COVID‐19 pandemic.
The Collected Works of Arne Beurling

Apparatus in a crop roll forming machine for improving the core formation of the crop rolls, reducing the amount of particles of crop material lost, and collecting particles of crop material lost from either the crop package or loose crop material during the roll formation process comprising stripping surfaces and an elongated tailgate with a collection pan. The particles are recycled from the collection pan back into the roll forming region by the cooperative interaction of the tailgate collection pan and the upper bale forming means as the bale forming means traverses a predetermined path imparting rotative motion to the crop material delivered to the roll forming region.
Pharmacological efficacies of Asparagus racemosus: A
review

Asparagus racemosus is acquainted as Satawar, Satmuli or Shatavari plays a vital role in the tradition of ayurveda possessing various therapeutic and ergogenic properties. It also has been proven to be the potent drug for controlling AIDS symptoms. Primary screening of root extract exposed the presence of secondary metabolites, including terpenoids, alkaloids, reducing sugar, flavonoids, steroids, saponin, and glycosides. Recent Research on A. racemosus revealed its anti-disease properties, such as antibacterial, immune-regulation, heart disease, and anti-stress, galactogogue effect etc. Different water and alcohol based extracts of roots, leaves, flowers, and stems of the Shatavari plant are good for treating female reproductive system problems. The antimicrobial activity result showed the spectrum of inhibition against the various pathogens. The present review article deals with major pharmacological efficacies of A. racemosus plant.
Biomarkers in a Cohort of HIV-Infected Patients Single- or Co-Infected with HTLV-1, HTLV-2, and/or HCV: A Cross-Sectional, Observational Study

HIV, HTLV-1/-2, and HCV share routes of transmission, and such virus co-infections could account for worse outcomes of associated diseases. Measuring cytokines/chemokines, CD4 and CD8 T cells, and HIV viral load (VL) in HIV single-infected and co-infected individuals has prognostic value. We analyzed such biomarkers in 129 blood samples of HIV-infected individuals matched for age and sex and divided into six groups (G1 (69 HIV); G2 (9 HIV/HTLV-1); G3 (6 HIV/HTLV-2); G4 (11 HIV/HCV); G5 (19 HIV/HCV/HTLV-1); and G6 (15 HIV/HCV/HTLV-2)). Eight cytokines/chemokines from fifteen analytes could be compared. The highest levels of Th1 and pro-inflammatory cytokines were detected in G2 (IFN-γ) and G6 (IL-6 and IL1-β) and of chemokines in G1 (MIG, IP10, RANTES), G4 (MCP1), and G6 (MIP1-β). The highest CD4 cells number and the lowest HIV VL were identified in G3 and the opposite results in G2. Positive correlations between CD4 and CD8 cells counts and IL-6 levels were detected in G2 and G5 and of HIV VL and RANTES in G4. Negative correlations were detected between CD8 and IFN-γ in G4 and HIV VL and RANTES in G6. Despite the small number of the cohort analyzed, and although the cross-sectional study design does not allow firm conclusions, the homogeneity of the characteristics of HIV/HTLV-co-infected individuals regarding age, time and route of HIV acquisition, and criteria for introducing ART enable us to suggest a negative impact of HTLV-1 and a possible protective role of HTLV-2 in HIV infection progression in such patients.
Differential Antecedents and Consequences of Affective and Cognitive Ruminations

Adopting the information processing perspective, the current study aims to investigate the differential effects of affective and cognitive ruminations on individuals’ affective states and learning behavior, and to further explore their differential mediating roles in transmitting effects of challenge and hindrance stressors on affect and behavior. A two-wave survey, in which stressors and ruminations were measured in the first wave and affective states and learning behavior were measured in the second, was conducted to obtain responses from 410 employees. As expected, affective and cognitive ruminations were differently associated with challenge stressors (i.e., cognitive job insecurity) and hindrance stressors (i.e., interpersonal conflict), and yielded different effects in terms of positive affect, negative affect, and learning behavior. Specifically, the results showed that: (a) cognitive job insecurity was significantly and positively related to cognitive rumination, while interpersonal conflict was significantly and positively related to affective rumination; (b) affective and cognitive ruminations were significantly associated with positive or negative affect, but in the exact opposite direction; (c) cognitive rumination, but not affective rumination, was significantly related to learning behavior; and (d) cognitive rumination mediated the effect of cognitive job insecurity on positive affect and learning behavior, while affective rumination mediated the effect of interpersonal conflict on negative affect. The current study contributes to the literature on rumination by introducing a new perspective, and sheds new light on the understanding of how and why affective and cognitive ruminations may lead to different affective states and behaviors.
Uniform regularity of measures on compact spaces.

Metric measure spaces enjoy certain countability properties which are normally lacking in the absence of metrizability. The problem of extending some of these properties to certain measures on completely regul r spaces recieved attention of many authors (see e.g. [1], [10], [11], [14] arid [18]). In [17], Zakon introduced the notion of "essential nestedness" of a uniformity with respect to a given measure on the uniform space X. His second paper [18] was devoted to the theory of "essential metrization". The problem was to find out what conditions can be added to "essential nestedness" to ensure "essential pseudometrizability". It can be shown that in the case of a Borel measure defined on a compact Hausdorff space, the condition of "essential nestedness' implies uniform metrization of the support of the measure; i.e. the measure is concentrated on a compact metric space in the first place [4].
“Targeting Design” of Nanoparticles in Tumor Therapy

Tumor-targeted therapy based on nanoparticles is a popular research direction in the biomedical field. After decades of research and development, both the passive targeting ability of the inherent properties of NPs and the active targeting based on ligand receptor interaction have gained deeper understanding. Unfortunately, most targeted delivery strategies are still in the preclinical trial stage, so it is necessary to further study the biological fate of particles in vivo and the interaction mechanism with tumors. This article reviews different targeted delivery strategies based on NPs, and focuses on the physical and chemical properties of NPs (size, morphology, surface and intrinsic properties), ligands (binding number/force, activity and species) and receptors (endocytosis, distribution and recycling) and other factors that affect particle targeting. The limitations and solutions of these factors are further discussed, and a variety of new targeting schemes are introduced, hoping to provide guidance for future targeting design and achieve the purpose of rapid transformation of targeted particles into clinical application.
Supportive Leadership and Post-Adoption Use of MOOCs

Educational institutions face significant challenges in extracting interest from their investments in massive open online courses (MOOCs). This study examined the impact of supportive leadership style on university employees' continued use of MOOCs and assessed the mediating role of their innovative work behavior. It uses a multi-theory perspective as opposed to the majority of past studies that use singular theoretical perspectives and extends the information system continuance (ISC) model with the leadership concept. Researchers collected multi-source dyadic data for this cross-sectional study from 632 employees and 316 supervisors from 19 Chinese universities. Data were analyzed using structural equation modeling with partial least squares through SmartPLS 3.2. 9. Results indicate supportive leadership influences employees' innovative behavior, which mediates between supportive leadership and employees' satisfaction, perceived usefulness, and intention to continue using MOOCs.
Is Education Beneficial to Environmentally Friendly Behaviors? Evidence from CEOs

Corporate environmental investment decisions play a crucial role in the protection of the public environment. As the decision-maker and executor, the environmental consciousness and social responsibility of the chief executive officer (CEO) has a long-term impact on the company’s environmental protection strategy, and the CEO’s level of education is a significant factor influencing the CEO’s environmental protection decisions. In this paper, we investigate the extent to which CEO education influences environmental protection investment decisions. A CEO education index is constructed as a proxy for CEO education based on the CEO’s educational background, using a panel sample of Chinese listed firms from 2010 to 2019 and providing robust evidence supporting the notioin that firms with highly educated CEOs are likely to engage in environmental protection spending activities. However, the positive relationship between CEO education and corporate environmental protection investment is reduced when the CEO also holds the position of chairman. The heterogeneity analysis shows that the positive relationship between CEO education and corporate environmental investment behavior is stronger in non-manufacturing and highly monopolistic market competitive industries. Our study contributes to the sustainability literature by providing a new impetus for corporate environmental activities from the perspective of CEO education and sheds light on the impact of the internal and external factors of firms on the investment in environmental protection. It may also help decision makers to decide whether to hire highly educated CEOs and use a dual structure of CEOs in markets with different levels of competition.
Sensitivity analysis of mesoscale simulations to physics parameterizations over the Belgian North Sea using Weather Research and Forecasting – Advanced Research WRF (WRF-ARW)

Abstract. The Weather Research and Forecasting (WRF) model offers a multitude of physics parameterizations to study and analyze the different atmospheric processes and dynamics that are observed in the Earth's atmosphere. However, the suitability of a WRF model setup is known to be highly sensitive to the type of weather phenomena and the type and combination of physics parameterizations. A multi-event sensitivity analysis is conducted to identify general trends and suitable WRF physics setups for three extreme weather events identified to be potentially harmful for the operation and maintenance of wind farms located in the Belgian offshore concession zone. The events considered are Storm Ciara on 10 February 2020, a low-pressure system on 24 December 2020, and a trough passage on 27 June 2020. A total of 12 WRF simulations per event are performed to study the effect of the update interval of lateral boundary conditions and different combinations of physics parameterizations (planetary boundary layer, PBL; cumulus; and microphysics). Specifically, the update interval of ERA5 lateral boundary conditions is varied between hourly and 3-hourly. Physics parameterizations are varied between three PBL schemes (Mellor–Yamada–Nakanishi–Niino, MYNN; scale-aware Shin-Hong; and scale-aware Zhang), four cumulus schemes (Kain–Fritsch, Grell–Dévényi, scale-aware Grell–Freitas, and multi-scale Kain–Fritsch), and three microphysics schemes (WRF Single-Moment five-class scheme, WSM5; Thompson; and Morrison). The simulated wind direction and wind speed are compared qualitatively and quantitatively to operational supervisory control and data acquisition (SCADA) data. Overall, a definitive best-case setup common to all three events is not identified in this study. For wind direction and wind speed, the best-case setups are identified to employ scale-aware PBL schemes. These are most often driven by hourly update intervals of lateral boundary conditions as opposed to 3-hourly update intervals, although it is only in the case of Storm Ciara that significant differences are observed. Scale-aware cumulus schemes are identified to produce better results when combined with scale-aware PBL schemes, specifically for Storm Ciara and the trough passage cases. However, for the low-pressure-system case this trend is not observed. No clear trend in utilizing higher-order microphysics parameterization considering the combinations of WRF setups in this study is found in all cases. Overall, the combination of PBL, cumulus, and microphysics schemes is found to be highly sensitive to the type of extreme weather event. Qualitatively, precipitation fields are found to be highly sensitive to model setup and the type of weather phenomena.
The Predictive Value of Barthel Score, Sequential Organ Failure Assessment Score, and D-Dimer in the 28-Day Prognosis of Patients with Non-ST Elevation Myocardial Infarction: A Retrospective Study of 358 Patients

Purpose To investigate the nursing prediction value of Barthel score, sequential organ failure assessment (SOFA) score and D-dimer on non-ST-elevation myocardial infarction (NSTEMI) inpatients. Methods The clinical data of 358 NSTEMI patients admitted to the emergency department were analyzed using logistic regression equation and a ROC curve was drawn. The area under ROC curve (AUC) of different indicators was compared. A COX regression model was created, and a survival curve was drawn. Results There were significant differences in age, D-dimer, WBC, NT-proBNP, EF (%), BI score, MEWS score, and SOFA score between the 28-day death group and the survival group (P < 0.05). The results showed that D-dimer (P = 0.002), SOFA score (P = 0.017), BI score (P < 0.001), and chest pain symptoms (P < 0.001) were independent predictors of 28-day death. When chest pain symptoms (AUC = 0.585), D-dimer (AUC = 0.945, Z = 8.00, P < 0.01), BI score (AUC = 0.145, Z = 5.36, P < 0.01), and SOFA score (AUC = 0.847, Z = 4.93, P < 0.01) were compared, the results showed that BI score (HR = 0.961, P < 0.01) and SOFA score (HR = 1.316, P < 0.001) had statistical significance on the 28-day survival time of the dead patients. Conclusion The Barthel score, SOFA score, and D-dimer are all essential in predicting the severity of NSTEMI patients, with a high nursing evaluation value. The Barthel and SOFA scores are associated with the risk of death within 28 days.
Comparison of Ultrasound Measurements for Diaphragmatic Mobility, Diaphragmatic Thickness, and Diaphragm Thickening Fraction with Each Other and with Lung Function in Patients with Chronic Obstructive Pulmonary Disease

Purpose To compare ultrasound measurements of diaphragmatic mobility, diaphragm thickness, and diaphragm thickening fraction with one another and also with lung function parameters in patients with chronic obstructive pulmonary disease (COPD). Patients and Methods We conducted a prospective, observational study from 2015 to 2018. A total of 140 patients were randomly selected for this study. Diaphragmatic thickness was measured at deep expiration and deep inspiration with a linear 10-MHz ultrasound probe. Diaphragm thickening fraction was calculated as the ratio between diaphragm thickness at deep inspiration and end expiratory diaphragm thickness. Diaphragmatic mobility was measured with a 3.5-MHz curved probe. Forced expiratory volume in one second (FEV1), residual lung volume, Pimax, and P0.1max were also measured. Sonographic results were compared to FEV1 and other lung function parameters. Results There was a significant positive correlation between diaphragmatic mobility and the following measurements: FEV1 (P < 0.01), diaphragm thickening fraction (P = 0.013), and lung function parameters reflecting ventilatory muscle strength such as Pimax (P < 0.017) and P0.1/Pimax (P < 0.01). There was a significant negative correlation between diaphragmatic mobility and both residual volume (P < 0.01) and diaphragmatic thickness (P = 0.022). In contrast, there was no correlation between diaphragmatic thickness and FEV1, Pimax, and P0.1/Pimax. Diaphragm thickening fraction had a significant correlation with FEV1 (P = 0.041). Conclusion In patients with COPD, diaphragm mobility measured sonographically correlates with different lung function parameters and also with sonographically measured diaphragm thickness (negative correlation) and diaphragm thickening fraction (positive correlation).
Sensory Evaluation of Common Ice Plant (Mesembryanthemum crystallinum L.) in Response to Sodium Chloride Concentration in Hydroponic Nutrient Solution

Common ice plant (Mesembryanthemum crystallinum L.) is a novel edible plant with a succulent and savory flavor. The plants display prominent epidermal bladder cells (EBCs) on the surface of the leaves that store water and sodium chloride (NaCl). The plants have high nutritional value and are adapted to saline soils. Previous research has determined the impact of NaCl on the growth and mineral content of ice plant, but as NaCl has an impact on a food’s sensory properties, an interesting question is whether saline growth media can affect the plant’s taste and texture, and if this alters consumers’ sensory response to ice plant. The objective of this study was to evaluate the sensory aspects of ice plant, as well as consumer liking in response to increasing NaCl concentration in hydroponic nutrient solution. Four-week-old seedlings of ice plant were transplanted into deep water culture (DWC) hydroponic systems and treated with five NaCl concentrations (0 M [control], 0.05 M, 0.10 M, 0.20 M, and 0.40 M NaCl). Eight-week-old plants (after four weeks of NaCl treatment) were harvested, and the middle leaves of each plant were sampled for consumer testing. A total of 115 participants evaluated various flavor, texture, and appearance aspects of ice plant and provided their liking ratings. The consumers were able to discriminate differences in salt intensity from the plants based on NaCl treatment in the hydroponic nutrient solution. Low NaCl concentrations (0.05–0.10 M) did not have obvious adverse effect on consumer liking, which aligns with the result of previous research that 0.05–0.10 M NaCl could largely stimulate the growth of ice plant. NaCl concentrations higher than 0.20 M are not recommended from both a production and consumer perspective. With increased NaCl level in plant samples, the consumers detected more saltiness, sourness, and fishiness, less green flavor, and similar levels of bitterness and sweetness. NaCl treatment had no effects on leaf appearance and texture, and the consumers’ overall liking was mainly determined by flavor. Overall, ice plant presents some unique attributes (salty and juicy) compared to other edible salad greens; however, consumer awareness of ice plant is very low, and purchase intent is relatively low as well. Consumers picture ice plant being used mainly in salads and in restaurants.
Coordinated Enactment: How Organizational Departments Work Together to Implement CSR

Research on the implementation of corporate social responsibility (CSR) has revealed the critical role of CSR departments vis-à-vis functional departments. While both CSR and functional departments influence CSR implementation, the question of how they work together remains underexamined. We address this question by mobilizing and merging two complementary yet separate perspectives on CSR implementation: “coordination” and “enactment. ” Building on a comparative case study involving seven large Swiss financial institutions that have established CSR departments and implemented CSR to varying extents, we inductively derive six courses of actions conducing to CSR implementation, involving both coordination and enactment. We distinguish between four courses of actions in the CSR departments (centralizing, coalescing, orchestrating, and consulting) and two courses of actions in the functional departments (decentralizing and tailoring). As our data suggest that coordination and enactment work in tandem, we capture these insights in a model of CSR implementation as coordinated enactment. Our research contributes to the literature by explaining how CSR departments and functional departments enact and simultaneously coordinate CSR at a particular implementation stage, thus illuminating how and why the variance in CSR implementation occurs.
Trophism and Homeostasis of Liver Sinusoidal Endothelial Graft Cells during Preservation, with and without Hypothermic Oxygenated Perfusion

Simple Summary Little is known about the functions and intracellular mechanisms of the endothelial cells in liver grafts. In particular, we still know little about the effect of the most recent machine perfusion techniques currently applied to improve liver transplant outcomes. In this study we analyzed different endothelial markers of both immunohistochemical and gene expression in two different biopsies (for each donor). We observed a severe depression of endothelial trophism in liver grafts, which is restored after reperfusion. This is interesting for further studies on liver grafts, especially considering that the execution of HOPE seems to improve this functional recovery. We propose that our results may help improve the knowledge on graft tissues in order to customize the perfusion techniques prior to transplant and, therefore, improve liver transplant outcomes. Abstract The aim of the present study was to evaluate the homeostasis and trophism of liver sinusoidal endothelial cells (LSECs) in vivo in different stages of liver graft donation, in order to understand the effects of graft ischemia and perfusion on LSEC activity in liver grafts. Special attention was paid to grafts that underwent hypothermic oxygenated perfusion (HOPE). Forty-seven donors were prospectively enrolled, and two distinct biopsies were performed in each case: one allocation biopsy (at the stage of organ allocation) and one post-perfusion biopsy, performed after graft implant in the recipients. In all biopsies, immunohistochemistry and RT-PCR analyses were carried out for the endothelial markers CD34, ERG, Nestin, and VEGFR-2. We observed an increase in CD34 immunoreactivity in LSEC during the whole preservation/perfusion period (p < 0.001). Nestin and ERG expression was low in allocation biopsies, but increased in post-perfusion biopsies, in both immunohistochemistry and RT-PCR (p < 0.001). An inverse correlation was observed between ERG positivity and donor age. Our results indicate that LSEC trophism is severely depressed in liver grafts, but it is restored after reperfusion in standard conditions. The execution of HOPE seems to improve this recovery, confirming the effectiveness of this machine perfusion technique in restoring endothelial functions.