Miracle-dz/UniFAR-FTUs huggingface dataset:
On the current sheets surrounding dipolarizing flux bundles in the magnetotail: The case for wedgelets

Using Time History of Events and Macroscale Interactions during Substorms observations from four tail seasons, we study the three‐dimensional structure of the dipolarization front current sheet (DFCS), which demarcates the magnetic boundary of a dipolarizing flux bundle (DFB, the strong magnetic field region led by a dipolarization front) in Earth's magnetotail. An equatorial cross section of the DFCS is convex; a meridional cross section is consistent with a dipolarized field line. The equatorial flow pattern in the ambient plasma ahead of the DFCS exhibits diversions of opposite sense on its evening and morning sides. The magnetic field perturbations are consistent with local field‐aligned current generation of region‐2 sense ahead of the front and region‐1 sense at the front. The median thickness of the DFCS increases from 800 to 2000 km with increasing distance from the neutral sheet, indicating bundle compression near the neutral sheet. On a meridional cross section, DFCS's linear current density (1.2–1.8 nA/m) peaks ~±0.55 l from the neutral sheet (where l is the ambient cross‐tail current sheet half‐thickness, l ~1.5 RE in our database). This peak, reminiscent of active‐time cross‐tail current sheet bifurcation noted in past studies, suggests that the intense but thin DFCS (10 to 20 nA/m2) may be produced by redistribution (diversion) of the extended but weaker cross‐tail current (~1 nA/m2). Near the neutral sheet, the average DFCS current over the dipolarization front (DF) thickness is perpendicular to both the magnetic field interior to the DFB and the average field direction over the DF thickness. Away from the neutral sheet, the average current becomes progressively parallel to the internal field and the average field direction. The average current directions are indicative of region‐1‐sense field‐aligned current on the DF. As few as approximately three DFBs can carry sufficient total current that, if redirected into the auroral ionosphere, can account for the substorm current wedge's peak current for a sizable substorm (~1 MA). A collapsing DFB could thus be an elemental substorm current wedge, or “wedgelet,” that can divert a sizable portion of the cross‐tail current into the auroral ionosphere.
Valencene, Nootkatone and Their Liposomal Nanoformulations as Potential Inhibitors of NorA, Tet(K), MsrA, and MepA Efflux Pumps in Staphylococcus aureus Strains

Valencene and nootkatone are aromatic sesquiterpenes with known biological activities, such as antimicrobial, antioxidant, anti-inflammatory, and antitumor. Given the evidence that encapsulation into nanosystems, such as liposomes, could improve the properties of several compounds, the present study aimed to evaluate the activity of these sesquiterpenes in their isolated state or in liposomal formulations against strains of Staphylococcus aureus carrying efflux pumps. The broth microdilution method evaluated the antibiotic-enhancing activity associated with antibiotics and ethidium bromide (EtBr). The minimum inhibitory concentration was assessed in strains of S. aureus 1199B, IS-58, and RN4220, which carry the efflux proteins NorA, Tet(K), and MsrA. In tests with strain 1199B, valencene reduced the MIC of norfloxacin and EtBr by 50%, while the liposomal formulation of this compound did not show a significant effect. Regarding the strain IS-58, valencene, and its nanoformulation reduced norfloxacin MIC by 60.3% and 50%, respectively. In the non-liposomal form, the sesquiterpene reduced the MIC of EtBr by 90%. Against the RN4220 strain, valencene reduced the MIC of the antibiotic and EtBr by 99% and 93.7%, respectively. Nootkatone and its nanoformulation showed significant activity against the 1199B strain, reducing the EtBr MIC by 21.9%. Against the IS-58 strain, isolated nootkatone reduced the EtBr MIC by 20%. The results indicate that valencene and nootkatone potentiate the action of antibiotics and efflux inhibitors in strains carrying NorA, Tet(K), and MsrA proteins, which suggests that these sesquiterpenes act as efflux pump inhibitors in S. aureus. Therefore, further studies are needed to assess the impact of incorporation into liposomes on the activity of these compounds in vivo.
Deblending using normal moveout and median filtering in common-midpoint gathers

The benefits of simultaneous source acquisition are compromised by the challenges of dealing with intense blending noise. In this paper, we propose a processing workflow for blended data. The incoherent property of blending noise in the common-midpoint gathers is utilized for applying median filtering along the spatial direction after normal moveout (NMO) correction. The key step in the proposed workflow is that we need to obtain a precise velocity estimation which is required by the subsequent NMO correction. Because of the intense blending noise, the velocity scan cannot be obtained in one step. We can recursively polish both the deblended result and the velocity estimation by deblending using the updated velocity estimation and velocity scanning using the updated deblended result. We use synthetic and field data examples to demonstrate the performance of the proposed approach. The migrated image of deblended data is cleaner than that of blended data and is similar to that of unblended data.
Treatment of Frequent or Chronic Primary Headaches in Children and Adolescents: Focus on Acupuncture

Background: Acupuncture is a spreading and promising intervention, which has proven to be very useful in the treatment and prevention of chronic pain, in particular chronic headaches, in adults; the literature about the treatment of pediatric chronic headaches is scarce. In addition, few guidelines advise its use in children. The aim of this review is to collect all relevant studies with available data about the use, effect, and tolerability of acupuncture as a treatment for pediatric primary headaches. Methods: This is a narrative review based on eight studies selected from 135 papers including pediatric cases treated with acupuncture for headache. Results: Despite the differences in tools, procedures, and application sites, acupuncture demonstrated a positive effect on both the frequency and intensity of headaches and was well tolerated. There are no studies considering the long-term efficacy of acupuncture. Conclusion: Further additional studies are needed on acupuncture in children and adolescents, with larger series and standardized procedures, in order to better assess efficacy, tolerability, and long-term prognosis and to define guidelines for the use of this promising and safe treatment. It is particularly relevant to identify safe and well-tolerated treatment options in pediatric patients affected by recurrent and debilitating headaches.
Tsunami-generated turbidity current of the 2011 Tohoku-Oki earthquake

We show the first real-time record of a turbidity current associated with a great earthquake, the Mw 9.0, 2011 Tohoku-Oki event offshore Japan. Turbidity current deposits (turbidites) have been used to estimate earthquake recurrence intervals from geologic records. Until now, however, there has been no direct evidence for large-scale earthquakes in subduction plate margins. After the 2011 Tohoku-Oki earthquake and tsunami, an anomalous event on the seafloor consistent with a turbidity current was recorded by ocean-bottom pressure recorders and seismometers deployed off Sendai, Japan. Freshly emplaced turbidites were collected from a wide area of seafloor off the Tohoku coastal region. We analyzed these measurements and sedimentary records to determine conditions of the modern tsunamigenic turbidity current. We anticipate our discovery to be a starting point for more detailed characterization of modern tsunamigenic turbidites, and for the identification of tsunamigenic turbidites in geologic records.
Interannual variability of the Madden‐Julian Oscillation and its impact on the North Atlantic Oscillation in the boreal winter

Interannual variability of the Madden‐Julian Oscillation (MJO) and its influence on the extratropical teleconnection are analyzed. It is found that there is an interannual shift of the MJO activity between the Indian Ocean and the western central Pacific. This is reflected by the year‐to‐year changes in the occurrence frequency of individual MJO phases. The leading mode of an empirical orthogonal function analysis of occurrence frequency of MJO phases shows an out‐of‐phase relationship between MJO phase 7 and phases 3–5. During winters when the MJO convection occurs more frequently in the Indian Ocean (phases 3–5), a winter mean positive North Atlantic Oscillation (NAO) tends to occur. These results indicate that the seasonal mean convection activity over the Indian Ocean related to the MJO is a possible driving forcing for the seasonal mean NAO variability in the boreal winter.
Effectiveness of Balance Rehabilitation Unit (BRU) Posturography Versus Conventional Rehabilitation in Patients With Unilateral Peripheral Vestibular Dysfunction

Background: Patients with unilateral peripheral vestibular deficit (UPVD) experience vertigo, dizziness, disability, negative influences on their quality of life, anxiety, and depression. In vestibular rehabilitation, virtual reality (VR) has proven to be effective. This investigation sought to evaluate the efficacy of the Balance Rehabilitation Unit (BRUTM) (MedicaaTM Montevideo, Uruguay, Balance Suite, version BRU 415) in patients with UPVD. Methods: A prospective, randomized, controlled study involved 38 patients from the Otoneurologic Service at the National Institute of Rehabilitation "Luis Guillermo Ibarra Ibarra" in Mexico. A physician specialist diagnosed the patients with UPVD and assigned them randomly to one of two groups. Group 1 (n = 19) received traditional vestibular rehabilitation, whereas Group 2 (n = 19) received BRUTM-supported vestibular rehabilitation. Both groups were monitored by medical professionals. Patients were evaluated with the Dizziness Handicap Inventory, static and dynamic balance assessments, the dynamic gait index, and the sensory organization test. The statistical analysis was conducted using the Student's t-test, with p 0.05 considered statistically significant. Results: The difference in mean age between the conventional therapy and BRUTM groups was not statistically significant. Both conventional vestibular rehabilitation and the BRUTM led to statistically significant improvements in all assessed parameters, with no statistically significant differences between the two groups. Conclusion: Balance, mobility, and quality of life were enhanced similarly in UPVD patients by BRUTM-supported vestibular rehabilitation and conventional vestibular rehabilitation. In addition, BRUTM facilitated patient motivation, exercise feedback, and confidence enhancement.
Tumor necrosis factor-alpha mediates the negative association between telomere length and kidney dysfunction

Aim/hypothesis: The relationship between peripheral blood leukocyte telomere length (LTL) and kidney dysfunction, especially in people with hypertension, remains unclear. No clinical study has explored the role of inflammation and oxidative stress in the relationship between LTL and kidney dysfunction. Therefore, we examined the relationship between baseline LTL and albuminuria progression and/or rapid renal function decline in Chinese patients with or without hypertension and investigated whether inflammation and oxidative stress played a mediating role in this relationship. Methods: We conducted a prospective study including 262 patients in a 7-year follow-up period from 2014 to 2021. Data on LTL, inflammation, oxidative markers, renal function, and urine protein levels were assessed. Kidney dysfunction was defined as either albuminuria progression, rapid decline in renal function, or the composite endpoint (albuminuria progression and rapid decline in renal function). Logistic regression and simple mediation models were used for the analysis. Results: In this cohort (mean age, 54.3±9.7 years; follow-up period, 5.9±1.1 years), 42(16.0%), 21(8.0%), and 59(22.5%) patients developed albuminuria progression, rapid eGFR decline, and the composite endpoint of kidney dysfunction, respectively. Logistic regression analysis showed that each standard deviation decrease of baseline LTL and the lower quartile (Q) of baseline LTL were significantly correlated with an increased risk of rapid decline in renal function (OR=1.83 [95% CI 1.07, 3.27] per 1SD, P=0.03; OR=7.57 [95% CI 1.25, 145.88] for Q1 vs. Q4, P for trend=0.031); and the composite endpoint of kidney dysfunction (OR=1.37 [95% CI 0.97, 1.96] per 1SD, borderline positive P=0.072; OR=2.96[95% CI 1.15, 8.2] for Q1 vs. Q4, P for trend=0.036). The mediating analysis showed that tumor necrosis factor (TNF)-a partly mediated the relationship between LTL and rapid decline in renal function (direct effect: β=0.046 95%CI [0.006, 0.090],P=0.02; indirect effect: β=0.013 95%CI [0.003, 0.020]), and the mediating proportion was 22.4%. In subgroup analyses, LTL was inversely associated with rapid decline in renal function or the composite endpoint of kidney dysfunction only in patients with hypertension (OR=49.07[3.72,211.12] vs.1.32[0.69,2.58] per 1SD, P for interaction=0.045;OR=3.10 [1.48, 7.52] vs.1.08[0.92,1.63] per 1SD, P for interaction=0.036). Conclusion: Baseline LTL could independently predict kidney dysfunction at follow-up, especially in participants with hypertension. TNF-a partially mediated the negative association between LTL and kidney dysfunction.
Approach of Supercritical Carbon Dioxide for the Extraction of Kleeb Bua Daeng Formula

Supercritical fluid extraction (SFE) is an innovative green technology for the extraction of phytochemicals from plants. Therefore, this study aimed to evaluate the application of SFE and to optimize the extraction conditions of the Thai herbal formula, Kleeb Bua Daeng (KBD). A Box–Behnken design (BBD) with response surface methodology (RMS) was used to determine the effect of the extraction time (30–90 min), temperature (30–60 °C), and pressure (200–300 bar) on response variables including the extraction yield, total phenolic content (TPC), total flavonoid content (TFC), total carotenoid content (TCC), and total anthocyanin content (TAC) of the KBD formula. The highest percentage extraction yield (3.81%) was achieved at 60 °C, 300 bar, and 60 min of the extraction time. The highest TPC (464.56 mg gallic acid equivalents/g extract), TFC (217.19 mg quercetin equivalents/g extract), and TCC (22.26 mg β-carotene equivalents/g extract) were all achieved at 60 °C, 250 bar, and 90 min of the extraction time. On the contrary, it was not possible to quantify the total anthocyanin content as anthocyanins were not extracted by this method. The results indicated that SFE-CO2 is a suitable method of extraction for a green recovery of phytochemicals with low and moderate polarity from the KBD formula.
The Influence of Technological Factors on Environmental Management Accounting Adoption in Libyan Oil Firms

This study investigates the extent influence of technological factors on the environmental management accounting (EMA) adoption. Technological, Organizational and Environmental (TOE) framework with Diffusion of Innovation (DOI) Theory is employed. The data in this study is collected by 44 questionnaires delivered to both of environmental and financial managers in Libyan oil firms. The findings show that most firms have a great intention and willingness to adopt EMA practices. The study found that both of technological characteristics (perceived benefits/ perceived importance) are significant factors for adopting EMA and therefore, more attention for enhancing employees’ awareness towards the importance and benefits of EMA adoption should be increased by top management in Libyan oil firms.
Identifying creative and participatory approaches to respond to existing challenges for Irish language teaching and learning at English-medium primary school level

ABSTRACT This paper argues that the combination of (i) creative language pedagogy informed by sociocultural theory (SCT), and (ii) a participatory, democratic approach to language learning inclusive of learner voice, supports language (re-) engagement for Irish language learners and educators in English-medium education, and in society at large. Firstly, existing challenges for Irish language learning and teaching at the primary level in English-medium education (EME) are explored within the broader context of Irish language engagement. In response, a school-based participatory action research (PAR) study which piloted SCT-informed pedagogical approaches of peer-tutoring, student-parent tutoring, and technology-mediated language learning is then presented. Focusing on overarching outcomes, the findings of this small-scale study are outlined which indicate an increase in both Irish language use and self-assessed proficiency, and overall motivation level consolidation amongst learners. In addition, the potential of a PAR approach in supporting engagement and partnership in Irish language learning is considered. In conclusion, recommendations for policy, practice, and research are suggested to further Irish language engagement in EME.
Scaling of maximum observed magnitudes with geometrical and stress properties of strike‐slip faults

We test potential scaling between observed maximum earthquake magnitudes along 27 strike‐slip faults with various properties including cumulative displacement, mapped fault length, seismogenic thickness, slip rates, and angle between fault strike and maximum horizontal stress. For 75–80% of the data set, the observed maximum scalar moment scales with the product of seismogenic thickness and either cumulative displacement or mapped fault length. Most faults from this population have slip rates >5 mm/yr (interplate faults), cumulative displacement >10 km, and relatively high angles to the maximum horizontal stress orientation. The remaining 20–25% population involves events at some distance from a plate boundary with slip rate <5 mm/yr, cumulative displacements <10 km, and ≈ 45° to the maximum horizontal stress. These earthquakes have larger magnitudes than the previous population, likely because of larger stress drops. The most likely interpretation of the results is that the maximum rupture length, and hence earthquake magnitudes, correlates with the cumulative displacement and the fault surface length. The results also suggest that progressive fault smoothing may lead to decreasing coseismic stress drops.
Uses and Gratifications of Digital Photo Sharing on Facebook

Despite the rapid adoption of Facebook as a means of photo sharing, minimal research has been conducted to understand user gratification behind this activity. In order to address this gap, the current study examines users’ gratifications in sharing photos on Facebook by applying Uses and Gratification (U&G) theory. An online survey completed by 368 respondents identified six different gratifications, namely, affection, attention seeking, disclosure, habit, information sharing, and social influence, behind sharing digital photos on Facebook. Some of the study’s prominent findings were: age was in positive correlation with disclosure and social influence gratifications; gender differences were identified among habit and disclosure gratifications; number of photos shared was negatively correlated with habit and information sharing gratifications. The study’s implications can be utilized to refine existing and develop new features and services bridging digital photos and social networking services.
Depression, Anxiety, and Stress Among Medical Students During COVID-19 at Sultan Qaboos University in Oman

Introduction With the spread of COVID-19 around the world, several interventions have been reported to be useful to control disease transmission. However, the impact of the pandemic on the mental health of medical students is underreported in the Arab world. This study aimed to explore the rates of depression, anxiety, and stress among medical students at Sultan Qaboos University (SQU) and to identify the factors associated with a higher risk of these mental disruptions. Method This was a cross-sectional study where medical students were approached to answer an online questionnaire via emails from the administrative affairs in the College of Medicine in SQU from 16/01/2021 to 18/05/2021. A 21-item depression, anxiety, and stress (DASS-21) scale was used as a self-reporting tool to measure the negative feelings of depression, anxiety, and stress. Results Out of 700 students, 184 (26.3%) students responded fully to the study questionnaire. More than half of the participants were females (58.7%, n=108), and the mean (SD) age was 20.31 (1.642). Most students were Omani (93.5%, n=172), and 34.2% (n=63) lived in Muscat. More than half of the students (51.6%) were in phase 2 of the academic years, in which the majority were considered within the cohort ≥2017 (81%, n=149), with a mean (SD) GPA of 2.9 (1.5). Scores from the DASS-21 scale showed that 29.4% vs 27.2% vs 14.7% had extremely severe depression vs anxiety and vs stress. The proportion of students who reported lower GPAs was significantly associated with higher scores of severe-to-extremely-severe depression (P=0.001), anxiety (P=<0.001), and stress (P=0.001). Living in Muscat vs other regions was associated with severe anxiety and stress (P=0.038 and P=0.007, respectively). Conclusion Similar to a few studies in Oman, this study confirms the high rates of depression, anxiety, and stress among medical students during the COVID-19 pandemic. Results may be utilized to alert decision-makers, student academic council, and academic authority to the need to adopt a preventive mental health policy and design guidelines with resilience measures for college students, including prolonged cognitive-behavioral interventions and recovery programs.
Biocontrol of Botrytis cinerea as Influenced by Grapevine Growth Stages and Environmental Conditions

The growth of four commercial biocontrol agents (BCAs: Bacillus amyloliquefaciens (BAD), Aureobasidium pullulans (APD), Metschnikowia fructicola (MFN), and Trichoderma atroviride (TAS)) was evaluated using turbidimetric assays on artificial substrates mimicking the chemical berry composition at four stages: pea-sized berries, veraison, softening, and ripe berries. The response of BCA growth differed among BCAs. Subsequently, the BCAs’ population size was assessed after 1 to 13 days of incubation on the substrate mimicking ripe berries at 15 to 35 °C. The population size of BAD increased with temperatures, while that of MFN decreased; the population sizes of APD and TAS showed bell-shaped patterns with lower growth at 15 or 35 °C. Finally, the BCAs were applied to ripe berries and then incubated at 15 to 30 °C. After 1 to 13 days, the berries were inoculated with B. cinerea and incubated for 7 days, after which the BCA control efficacy was assessed. The highest control was observed at 25 °C for BAD and APD, at 15 to 20 °C for MFN, and at 25 to 30 °C for TAS. The results confirm that the plant substrates and temperature affect the population size of the BCA following application; temperature also affects the preventative efficacy of BCA against B. cinerea.