Miracle-dz/UniFAR-FTUs huggingface dataset:
A nomogram prediction model based on clinicopathological combined radiological features for metachronous liver metastasis of colorectal cancer

Objective: To establish a nomogram prediction model (based on clinicopathological and radiological features) for the development of metachronous liver metastasis (MLM) in patients with colorectal cancer (CRC). Methods: This retrospective study included patients with CRC who underwent surgery at Changshu No.1 People's Hospital and the Second Affiliated Hospital of Soochow University between January 2016 and December 2018. The clinical, pathological, and radiological features of each patient were investigated. Risk factors for MLM were identified by univariable and multivariable analyses. The predictive nomogram for MLM development was constructed. The predictive performance of the nomogram was estimated by the receiver operating characteristics curve, calibration curve, and decision curve analysis. Results: This study included 161 patients with CRC [median age: 66 (range, 33-87) years]. Fifty-nine developed MLM after a median of 12 (range, 2-52) months after surgery. The multivariable logistic regression analysis showed that age >66 years (OR=3.471, 95% CI: 1.272-9.473, P=0.015), N2 stage (OR=6.534, 95% CI: 1.456-29.317, P=0.014), positive vascular invasion (OR=2.995, 95% CI: 1.132-7.926, P=0.027), positive tumor deposit (OR=4.451, 95% CI: 1.153-17.179, P=0.030), and linear (OR=6.774, 95% CI: 1.306-35.135, P=0.023) and nodal pericolic fat infiltration patterns (OR=8.762, 95% CI: 1.521-50.457, P=0.015) were independently associated with MLM. These five factors were used to create a nomogram. The area under the receiver operating characteristics curve of the nomogram was 0.866 (95% CI: 0.803-0.914), indicating favorable prediction performance. The calibration curve of the nomogram showed a satisfactory agreement between the predicted and actual probabilities. Conclusions: A nomogram prediction model based on five clinicopathological and radiological features might have favorable prediction performance for MLM in patients who underwent surgery for CRC. Hence, the present study proposes a nomogram that can easily be used to predict MLM after CRC surgery based on readily available features.
Early pottery in the North American Upper Great Lakes: exploring traces of use

Abstract Why was pottery developed and adopted? Food residues on ceramic material from three sites in the Upper Great Lakes region of North America suggest that there is no single answer, and contradict previous indications that pottery was created for the ritual processing of fish oil. Samples from two sites showed evidence of both plant and animal remains, but no fish oils were detected, even for the site believed to be a fishing camp. Nut oils dominated for the third site, being present on both fire-cracked rocks and pottery, and were suggestive of an acorn-rendering process. All of the vessels were ideally suited to slow simmering, but it seems that their applications were diverse.
Predicting Short- and Long-Term Functional Outcomes Based on Serum S100B Protein Levels in Patients with Ischemic Stroke

Background: Ischemic stroke is one of the leading causes of mortality and disability. The neuroimaging methods are the gold standard for diagnostics. Biomarkers of cerebral ischemia are considered to be potentially helpful in the determination of the etiology and prognosis of patients with ischemic stroke. Aim: This study aimed to investigate the usefulness of serum S100B protein levels as a short- and long-term prognostic factor in patients with ischemic stroke. Study design and methods: The study group comprised 65 patients with ischemic stroke. S100B protein levels were measured by immunoenzymatic assay. Short-term functional outcome was determined by the NIHSS score on day 1 and the difference in the NIHSS scores between day 1 and day 9 (delta NIHSS). Long-term outcome was assessed by the modified Rankin Scale (MRS) at 3 months after the stroke. At the end of the study, patients were divided into groups based on the NIHSS score on day 9 (0–8 “good” and >8 “poor”), the delta NIHSS (“no improvement” ≤0 and >0 “improvement”), and the MRS (“good” 0–2 and >2 “poor”). Differences in S100B levels between groups were analyzed with the ROC curve to establish the optimal cut-off point for S100B. The odds ratio was calculated to determine the strength of association. Correlations between S100B levels at three time points and these variables were evaluated. Results: We revealed a statistically significant correlation between S100B levels at each measurement point (<24 h, 24–48 H, 48–72 h) and the NIHSS score on day 9 (R Spearman 0.534, 0.631, and 0.517, respectively) and the MRS score after 3 months (R Spearman 0.620, 0.657, and 0.617, respectively). No statistically significant correlation was found between S100B levels and the delta NIHSS. Analysis of the ROC curve confirmed a high sensitivity and specificity for S100B. The calculated AUC for the NIHSS on day 9 were 90.2%, 95.0%, and 82.2%, respectively, and for the MRS, 83.5%, 83.4%, and 84.0%, respectively. After determining the S100B cut-off, the odds ratio for beneficial effect (NIHSS ≤ 8 at day 9 or MRS 0–2 after 3 months) was determined for each sampling point. Conclusion: S100B is a useful marker for predicting short- and long-term functional outcomes in patients with ischemic stroke.
The Effect of Axial Traction MRI on the Articular Cartilage Visibility in Thumb Carpometacarpal Arthritis

Objectives: Thumb carpometacarpal arthritis has a high incidence. However, the degree of damage to the cartilage has not been accurately assessed. The purpose of this study was to examine the effects of axial traction of the thumb carpometacarpal joint during magnetic resonance imaging (MRI) on the visibility of articular cartilage in patients with thumb carpometacarpal arthritis and to evaluate the articular cartilage defect using MRI findings. Materials and methods: Forty-four patients with thumb carpometacarpal arthritis (14 males, 30 females) and a mean age of 67.3±8.6 years were classified according to Eaton Stages 1, 2, 3, and 4 in 2, 14, 24, and 4 patients, respectively. Axial traction MRI was performed with and without traction (3 kg) using 3-Tesla MRI (Siemens Magnetom Skyra) with a 3D T2* multiecho data imaging combination. The effectiveness of traction was verified using the joint space width before and after traction at five points (central, volar, dorsal, radial, and ulnar margins) and the original articular cartilage outline visibility classification (poor, intermediate, complete). The rate of remaining cartilage on each joint surface was also evaluated. Statistical significance was set at p<0.05 in this study. Results: Joint space width increased significantly at all points with traction (P<0.01). The grade of articular cartilage outline visibility significantly improved from seven intermediate and 37 poor cases to 15 complete, 23 intermediate, and six poor cases (P<0.01). Significantly more articular cartilage remained in Stages 1-2 compared with Stages 3-4 arthritis of both articular surfaces (P<0.01 in first metacarpal, P=0.01 in trapezium). Conclusion: Axial traction of the thumb increased the joint space width and improved articular cartilage visibility in the thumb carpometacarpal joint. Our results suggested that axial traction MRI can be used for noninvasive evaluation of articular cartilage defects in patients with thumb carpometacarpal arthritis and aid in selecting the optimal surgical procedure.
Vitamin D Deficiency in Children and Adolescents in Saudi Arabia: A Systematic Review

Vitamin D deficiency is a globally recognized health concern, with particular prominence in specific geographies and demographics. Saudi Arabia, with its unique climatic conditions and cultural practices, has been under scrutiny regarding the prevalence of this deficiency, especially among children and adolescents. This systematic review aimed to assess the prevalence of vitamin D deficiency among children and adolescents in Saudi Arabia by compiling and analyzing various studies to offer a comprehensive view of the situation. The comprehensive web search encompassed a range of databases, including Google Scholar and PubMed, to gather studies published between 2012 and 2023. An analysis was conducted on seven studies, totaling 2,429 participants, with each study focusing on various aspects, regions, and cohorts within Saudi Arabia. These studies employed different methodologies, ranging from cross-sectional surveys to randomized clinical trials. The review unveiled an alarming prevalence of vitamin D deficiency in the studied population. On average, around 81.1% of children and adolescents showcased inadequate vitamin D levels. Specific vulnerable groups, such as those with Type 1 diabetes mellitus or asthma, had pronounced deficiencies. Factors influencing these levels ranged from dietary habits, sun exposure, physical activity, and socioeconomic parameters. The compelling evidence from the studies underscores a consistent health issue among the pediatric population in Saudi Arabia that the overwhelming majority of Saudi children and adolescents lack adequate vitamin D. Addressing this widespread deficiency needs a multifaceted approach. Implementing policies that support vitamin D food fortification, encouraging routine screenings, and launching public awareness campaigns about safe sun exposure and diet can play a transformative role in this health crisis.
The Pattern and Progression of “Usual” Interstitial Pneumonia with Autoimmune Features: Comparison with Patients with Classic Interstitial Pneumonia with Autoimmune Features and Idiopathic Pulmonary Fibrosis

Background: We proposed the term “UIPAF” to define patients with Usual Interstitial Pneumonia (UIP) associated with only one domain of the classification called “Interstitial Pneumonia with Autoimmune Features” (IPAF). The objective of this study was to evaluate the clinical presentation and prognosis of UIPAF patients, compared with two cohorts, composed of IPAF and idiopathic pulmonary fibrosis (IPF) patients, respectively. Methods: The patients were enrolled as IPAF, UIPAF, or IPF based on clinical, serological, and radiological data and evaluated by a multidisciplinary team. Results: We enrolled 110 patients with IPF, 69 UIPAF, and 123 IPAF subjects. UIPAF patients were similar to IPAF regarding autoimmune features, except for the prevalence of Rheumatoid Factor in UIPAF and anti-SSA in IPAF. A similar proportion of the two cohorts progressed toward a specific autoimmune disease (SAD), with differences in the kind of SAD developed. The real-life management and prognosis of UIPAF patients proved to be almost identical to IPF. Conclusions: UIPAF shared with IPAF similar autoimmune features, suggesting the opportunity to be considered IPAF, excluding the morphological domain by the classification. However, the real-life management and prognosis of UIPAF are similar to IPF. These data suggest a possible modification in the therapeutic management of UIPAF.
Correlation between sarcopenia and cirrhosis: a meta-analysis

Background The relationship between sarcopenia and cirrhosis is unclear. In this research, our aim is to evaluate the prevalence of sarcopenia among individuals with liver cirrhosis and its correlation with survival and mortality risks. Methods We conducted searches on PubMed, Web of Science, EMBASE, and Cochrane for English articles published up to July 10, 2023, and additionally manually searched the bibliography of relevant articles. We incorporated research on sarcopenia in patients with cirrhosis to examine the connection between sarcopenia and the likelihood of survival and mortality. Statistical analyses were carried out utilizing the Stata version 15.1 software. Depending on the heterogeneity of the results, we employed either fixed-effects models or random-effects models for data synthesis. To assess publication bias, we employed funnel plots and conducted Egger’s test. Results We included 40 studies involving 8,945 patients with cirrhosis. The overall prevalence of cirrhosis was 41% (95% CI 34%–48%). Male patients and those with liver cirrhosis and hepatic encephalopathy had a higher prevalence of sarcopenia (44% for male patients and 48% for hepatic encephalopathy patients). Sarcopenia emerged as a risk factor for both survival (HR = 2.57, 95% CI 2.02–3.27, p < 0.001) and mortality (HR = 2.13, 95% CI 1.86–2.44, p < 0.001) in patients with cirrhosis. Subgroup analyses consistently yielded the same results for study sites, whether HCC patients were excluded from the cohort, whether patients were from the liver transplant cohort or had undergone tips surgery, the definition of sarcopenia (L3-SMI or other methods), and the diagnostic criteria used by patients. The presence of sarcopenia was also a significant risk factor for hepatic encephalopathy [HR = 2.27, 95% CI (1.76–2.94), p < 0.001]. Conclusion This systematic review and meta-analysis reveal that patients with cirrhosis have a prevalence of sarcopenia of 41% and is associated with survival rate and mortality rate. Therefore, we should attach importance to the screening of sarcopenia in patients with cirrhosis, early detection of susceptible populations, and appropriate measures to reduce the occurrence and adverse outcomes. Systematic review registration:https://www.crd. york.ac. uk/PROSPERO/#recordDetails.
Variability of Salinity in Pará River Estuary: 2D Analysis with Flexible Mesh Model

ABSTRACT Rosário, R.P., Borba, T.A. C. , Santos, A.S. , and Rollnic, M. , 2016. Variability of Salinity in Pará River Estuary: 2D Analysis with Flexible Mesh Model. In: Vila-Concejo, A. ; Bruce, E. ; Kennedy, D.M. , and McCarroll, R.J. (eds.), Proceedings of the 14th International Coastal Symposium (Sydney, Australia). Journal of Coastal Research, Special Issue, No. 75, pp. 128–132. Coconut Creek (Florida), ISSN 0749-0208. This research aims to study the spatial and temporal variability of the salinity in the Pará River Estuary. The Pará River estuary is among the largest in Brazil, with a mouth of approximately 60 km wide. The Pará River is not a true river because it does not have a spring, but is a hydrographic mesh that receives outflow of several water bodies. There is an ingestion of salt in the Pará River Estuary, different of what occurs within Amazon River, that leads estuarine characteristics onto the continental shelf. The model was implemented based on flexible mesh in the estuarine area of the Amazon River and Pará River basin for one-year simulation. The software D-Flow FM was used to perform hydrodynamic model and, D3D-D-Waq to water quality model. These experiments support a conceptual description of haline dynamics of this system to produce information regarding different scenarios in the region. Fieldworks were made (25h - three points in estuary) in low, high, and transitional rivers discharge in order to evaluate the model performance. The main conclusions are: the numerical modeling showed an upstream saline intrusion about 130 km for the dry period (October to December) and about 70 km for the rainy period (January to May). 2D barotropic condition shows river discharge as the most important force that control the variation of saline intrusion due to the reduction of freshwater flow in the system.
Infisdial as Learning Media for Strengthening "Anti Bullying" Attitudes

Bullying is increasingly common in Indonesia, especially in school environments. Teachers have a very important contribution to overcoming bullying behavior towards students, one of which is by providing interesting but still effective learning to transform knowledge and information as well as life values through learning at school. The learning process can be carried out using learning media. The aim of this research is to develop infographic-based learning media through social media that can strengthen students' anti-bullying attitudes. This development uses the ADDIE model. This study involving material experts and media experts, as well as Pancasila Education subject teachers and 30 Phase E students as research subjects. Data collection was carried out using questionnaires and interviews. At the validation stage, the material expert received the "Very good" category. The results of the Independent Sample T-test were interpreted to show that the calculated t value was greater than the t table so that it could be concluded that H0 was rejected and H1 was accepted with the test decision being that the experimental class mean was greater than the control class. This shows that treatment using informal media has a significant impact on strengthening the value of anti-bullying attitudes in students.
Regional Variability in the Prevalence of Food Insecurity and Diet Quality among United States Children

Understanding the association between food security status (FSS) and diet quality in children is crucial. This study investigated regional variability in FSS, participation in the federal nutrition assistance program (FNAP), and diet quality among US children. National Health and Nutrition Examination Survey (NHANES) data from 2013 to 2016 were analyzed. The association between FSS, FNAP participation, and diet quality (Healthy Eating Index—HEI-2015) was assessed using multiple linear/logistic regression models. The sample included 6403 children (mean age: 7.5 years; 51% male; 33% Hispanic). Within the sample, 13% reported child food insecurity, and 30% reported household food insecurity. Additionally, 90% participated in the FNAP, and 88% were enrolled in school lunch programs. Children in urban areas were significantly more likely to report household food insecurity than those in rural areas (29.15% vs. 19.10%). The overall HEI-2015 score was 48.2. The associations between child/household FSS and FNAP participation as well as between child/household FSS and diet quality did not differ by urban/rural residence status, irrespective of the children’s age groups. There is a need for improvement in children’s diet quality, regardless of age or urban/rural residence. The findings suggest that improving children’s diets requires broader action as well as the prioritizing of children in urban areas experiencing food insecurity in future dietary interventions.
Green Restorative Justice: Environmental Enforcement and Justice

Objective: Provides a framework for investigating potential green restorative justice initiatives in Indonesia to address environmental legislation. Time, money, and equity are all preserved in green restorative justice eco-friendly restitution For long-term ecological regulation. Method: This study employs a sociolegal strategy incorporating a green restorative justice framework to address environmental legal issues. After that, we did some conceptual research. Results: Explores the possibility of green restorative justice as an additional approach to resolving environmental issues. There are time and money savings with the green restorative justice method. Another discovery is that when other stakeholders, including the government and the media, oversee these cases, implementing ecosystem greening for guilty corporations may be speedier and more beneficial for society. Conclusion: Explores the possibility of green restorative justice as an additional approach to resolving environmental issues. More expedited, less expensive, and more equitable is the green restorative justice approach. Businesses that are to blame may have ecosystem greening implemented more quickly and to society's benefit with the help of this study to create environmentally friendly enforcement that lasts.
Longitudinal Analysis of Co-Curricular Involvement Among Engineering Undergraduates: Exploring Timing, Type, and Self-Reported Skills Development

The purpose of this study is to explore the self-reported professional competencies gained by engineering students involved at different rates and types of co/extra-curricular activities (CECAs) between their grade 12 and junior years of undergraduate engineering education. The contribution of this work is in using longitudinal data to understand how student engagement and learning outcomes might evolve to inform potential co-curricular programming changes. We analyzed data from an annual professional development survey from 970 students from 2016-2019. Findings show that higher engagement may not necessarily lead to higher skill acquisition for all students per unit of time, particularly in engineering-focused facets of professional skills. Co-curricular spaces are prone to be dominated by certain demographic profiles, and students are likely to engage in nontechnical work and clubs, as compared to co-curricular projects and research experiences. We conclude that future work should attempt to specify the “goldilocks” level of involvement, understand barriers to participation, and robustly characterize the nature of learning and students’ recognition of their learning through CECAs.
The governance involvement in the relationship between earnings management and surplus free cash flow

The purpose of this study is to examine empirically the association between surplus free cash flow (SFCF) and earnings management (EM), and the moderating effect of governance on this relationship. The study used a sample of non-financial companies listed on the Amman Stock Exchange (ASE) over the ten-year period (2011–2020) with all the information necessary to estimate the study variables. The modified Jones (1991) model is used to estimate discretionary accruals, a widely used proxy for earnings management. Based on the regression analysis of the related panel data collected, the study’s findings indicate that SFCF is positively associated with EM activities. This result is consistent with most prior related study’s findings (Nouri & Gilaninia, 2017; Rahmawati, 2020) and suggests that when growth opportunities are limited, the free cash flow induces management to involve in upward management practices. Additionally, results indicate a significant negative impact of the interaction variable SFCF*AQ (audit quality) on EM, suggesting that, in an SFCF situation, AQ reduces manager’s tendency to involve in upward EM practices. The study’s results are likely to be useful for accounting researchers, local governmental bodies, and policymakers who are concern with the impact of EM practices on the quality of earnings.
The Correlation Between ABO Blood Group and Rhesus Factor in Patients with Periodontal Diseases: Review Subject

Periodontal diseases can be defined as a wide range inflammatory condition due to the infection with pathogenic bacteria grow in oral cavity affecting the supporting structure of the teeth. Local plus systemic conditions are affected the initiating and progressing of periodontal infections. Blood groups and Rh factor may play important role in periodontal illness. The aim of present study was to find if there are relation between ABO blood groups and Rhesus factor with periodontal status and if they are possible risk factors or not according to many studies that were done throughout the world.
OFDM-Based Information Harvesting

Considering the current capability in hardware design, wireless power transmission enables the next stage in the current consumer electronics revolution by reducing the dependency on the lifetime of the batteries in the devices. Information harvesting (IH) introduced a novel mechanism by enabling information transmission to the existing far-field wireless power transfer mechanisms. To do so, information bits are embedded into a transmitter entity at the wireless power transmitter inspired by index modulation techniques creating a communication link without sacrificing the operational objectives of the power transmitter. This letter proposes a new IH mechanism on top of orthogonal frequency division multiplexing-based far-field wireless power transfer mechanism. The benefits of the proposed IH mechanism are investigated in terms of harvested energy, achievable rate and reliability.