Miracle-dz/UniFAR-FTUs huggingface dataset:
Live wildlife trade in markets - a scoping review to inform risk assessment of emerging infectious diseases

Wet markets are important for food security in many regions worldwide but have come under scrutiny due to their potential role in the emergence of infectious diseases. The sale of live wildlife has been highlighted as a particular risk, and the World Health Organisation has called for the banning of live, wild-caught mammalian species in markets unless risk assessment and effective regulations are in place. Following PRISMA guidelines, we conducted a global scoping review of peer-reviewed information about the sale of live, terrestrial wildlife in markets that are likely to sell fresh food, and collated data about the characteristics of such markets, activities involving live wildlife, the species sold, their purpose, and animal, human, and environmental health risks that were identified. Of the 59 peer-reviewed records within scope, only 25% (n = 14) focussed on disease risks; the rest focused on the impact of wildlife sale on conservation. Although there were some global patterns (for example, the types of markets and purpose of sale of wildlife), there was wide diversity and huge epistemic uncertainty in all aspects associated with live, terrestrial wildlife sale in markets such that the feasibility of accurate assessment of the risk of emerging infectious disease associated with live wildlife trade in markets is limited. Given the value of both wet markets and wildlife trade and the need to support food affordability and accessibility, conservation, public health, and the social and economic aspects of livelihoods of often vulnerable people, there are major information gaps that need to be addressed to develop evidence-based policy in this environment. This review identifies these gaps and provides a foundation from which information for risk assessments can be collected.
Differentiating Nanomaghemite and Nanomagnetite and Discussing Their Importance in Arsenic and Lead Removal from Contaminated Effluents: A Critical Review

Arsenic and lead heavy metals are polluting agents still present in water bodies, including surface (lake, river) and underground waters; consequently, the development of new adsorbents is necessary to uptake these metals with high efficiency, quick and clean removal procedures. Magnetic nanoparticles, prepared with iron-oxides, are excellent candidates to achieve this goal due to their ecofriendly features, high catalytic response, specific surface area, and pulling magnetic response that favors an easy removal. In particular, nanomagnetite and maghemite are often found as the core and primary materials regarding magnetic nanoadsorbents. However, these phases show interesting distinct physical properties (especially in their surface magnetic properties) but are not often studied regarding correlations between the surface properties and adsorption applications, for instance. Thus, in this review, we summarize the main characteristics of the co-precipitation and thermal decomposition methods used to prepare the nano-iron-oxides, being the co-precipitation method most promising for scaling up processes. We specifically highlight the main differences between both nano-oxide species based on conventional techniques, such as X-ray diffraction, zero and in-field Mössbauer spectroscopy, X-ray photoelectron spectroscopy, X-ray absorption spectroscopy, and X-ray magnetic circular dichroism, the latter two techniques performed with synchrotron light. Therefore, we classify the most recent magnetic nanoadsorbents found in the literature for arsenic and lead removal, discussing in detail their advantages and limitations based on various physicochemical parameters, such as temperature, competitive and coexisting ion effects, i.e., considering the simultaneous adsorption removal (heavy metal–heavy metal competition and heavy metal–organic removal), initial concentration, magnetic adsorbent dose, adsorption mechanism based on pH and zeta potential, and real water adsorption experiments. We also discuss the regeneration/recycling properties, after-adsorption physicochemical properties, and the cost evaluation of these magnetic nanoadsorbents, which are important issues, but less discussed in the literature.
Polarization imaging reflectometry in the wild-supplemental material

TRS Transmitted Radiance Sinusoid DOLP Degree of Linear Polarization ρd Difuse albedo fr (σ ;η; ω⃗i , ω⃗o ) Specular BRDF n⃗ Surface normal Li (ω⃗i ) Incoming radiance θB Brewster angle E∥ Unit vector parallel to the plane of incidence E⊥ Unit vector perpendicular to the plane of incidence R∥ Relectance of p-polarized light R⊥ Relectance of s-polarized light δ Phase retardation between the orthogonally projected images of the electric vector Imax Maximum intensity of the Transmitted Radiance Sinusoid (TRS) Imin Minimum intensity of the Transmitted Radiance Sinusoid (TRS) φ Angular phase of the TRS φo Angle of rotation of the polariser with respect to camera coordinates xi,o,r ef Subscript indicates input (i), output (o) or relection (ref), where x can be any symbol listed thereafter P Degree of Linear Polarization (DOLP) ψ Angle of polarization expressed in local coordinates χ Ellipticity angle expressed in local coordinates ω⃗ Unit direction in spherical coordinates (ω⃗ = (θ , φ )) s Stokes vector (s = [s0 s1 s2 s3] T )
Efficacy and safety of guselkumab for the treatment of patients with moderate-to-severe plaque psoriasis: A meta- analysis of randomized clinical trials

Purpose: To conduct a systematic analysis on data from randomized controlled trials (RCTs) on different doses of guselkumab, and provide high-quality evidence for its use in the treatment of patients with moderate-to-severe plaque psoriasis (PsO). Methods: Related studies were searched using online search engines including MEDLINE, PubMed, and central registry of Cochrane controlled trials from January 2001 to October 2017. Only randomized, placebo-controlled, double-blind clinical trials involving guselkumaband placebo-treated PsO subjects were included. Results: Five eligible double-blind, randomized, and placebo-controlled trials involving patients with moderate-to-severe PsO subjects treated with guselkumab were included. Compared with the placebo groups, the proportion of patients with improvements in Psoriasis Area and Severity Index (PASI) 75 (RR= 12.14; 95% CI= 9.11-16.16; p < 0.001); PASI 90 (RR= 23.26; 95% CI =14.57-37.13; p < 0.001), and PASI 100 (RR = 37.66; 95% CI = 15.81-89.69; p < 0.001) were significantly higher than those in guselkumab-treated groups. Furthermore, the guselkumab-treated groups showed significant decreases in Physician’s Global Assessment (PGA) score (RR = 10.46; 95% CI = 7.96-13.83; p < 0.001) and the Dermatology Life Quality Index (DLQI) score (SMD = -1.3; 95% CL = -1.4 to -1.19; p < 0.001), when compared with the placebo groups. However, there were no significant differences in adverse events (AEs) (RR = 1.01; 95% CL = 0.93-1.11; p > 0.05); severe adverse events (SAEs) (RR = 1.32; 95% CI =0.69-2.54; p > 0.05) and study discontinuations (RR = 0.79; 95% CI = 0.42-1.48; p > 0.05) between the two groups. Conclusion: This meta-analysis summarizes available evidence for the use of guselkumab in psoriasis. The results suggest that guselkumab is superior to placebo in moderate-to-severe psoriasis, and is welltolerated, effective, and safe in improving the severity of disease and quality of life.
Forage yield and morphological composition of native maize under semi-arid conditions

Environmental conditions in semi-arid areas limit the productivity of forage species used in animal feed; however, corn (Zea mays L.) has a wide adaptation to different environmental conditions of temperature, precipitation, altitude, soil, among others. The objective of the present study was to evaluate the yield and morphological composition of ten native corn genotypes, a hybrid and a synthetic variety, during the cycle Spring-Summer 2017. A randomized complete block experimental design was used, and an analysis of variance was performed; the means of the treatments were compared with the Tukey test. The variables evaluated were: yield of total dry matter (TDM), and by morphological component: leaf (lDM), stem (sDM), ear (eDM), panicle (pDM) and dead matter (dmDM), plant height (PH), number of leaves (NL), leaf length (LL), leaf width (LW) and the leaf/stem ratio (L/S). The highest and lowest TDM yield was obtained by the Raton×Tuxpeño Norteño genotype and the A6-069-B hybrid, with 8 888 and 3 113 kg DM ha, respectively. The highest height (180 cm) was obtained by the genotypes Raton×Tuxpeño Norteño and Olotillo×Tuxpeño. The largest number of leaves number was presented by the genotype Tuxpeño Norteño×Olotillo with 11.6. The largest leaf:stem ratio (2.1) was in the synthetic variety Breve Padilla. More research is needed on the improvement by recurrent selection of the Raton×Tuxpeño Norteño genotype to obtain a higher yield and nutritional value in corn fodder.
CMAR_A_231042 4227..4239

Oncology Surgery Department, Beijing Shijitan Hospital, Capital Medical University (Peking University Ninth School of Clinical Medicine), Beijing 100038, People’s Republic of China Introduction: Increasing studies have demonstrated that noncoding RNAs, including miRNAs and lncRNAs, have vital roles in mediating cancer progression. However, the expression features and biological functions of LINC00689 in gastric cancer (GC) remain largely unknown. This study was designed to investigate the functions of LINC00689, miR526b-3p and ADAM9 as well as their interactions in GC. Methods: Real time PCR(RT-PCR) was used to detect the expression of LINC0068, miR526b-3p and ADAM9 in both GC tissues or cell lines. Gainand lossof functions of assays were conducted to verify the role of LINC0068, miR-526b-3p and ADAM9 in GC development. Cell proliferation were determined by CCK8 assay and transwell assay and scratch wound-healing assay were used to test cell invasion and migration. Further, the relationships between LINC00689 and miR-526b-3p, miR-526b-3p and ADAM9 were predicted by bioinformatics analysis and then proved by Luciferase reporter assay and RNA Immunoprecipitation(RIP) assay. Results: We found that LINC00689 was upregulated in GC tissues and positively correlated with advanced tumor stage and tumor size, while miR-526b-3p was downregulated. Furthermore, gainand loss-of-function experiments revealed that LINC00689 promoted the proliferation, migration, invasion and epithelial-mesenchymal transition (EMT) of GC cells, while miR-526b-3p had the opposite effects. The underlying mechanisms indicated that LINC00689 functioned as a competing endogenous RNA (ceRNA) by sponging miR-526b-3p in GC cells. Further investigations confirmed that ADAM9 was a direct target of miR-526b-3p and positively modulated the progression of GC. Conclusion: Our study suggests that LINC00689 functions as a novel oncogenic lncRNA in the development of GC by promoting ADAM9 expression through suppression of miR-526b-3p.
Quantifying Southern Annular Mode paleo-reconstruction skill in a model framework

Abstract. Past attempts to reconstruct the Southern Annular Mode (SAM) using paleo-archives have resulted in records which can differ significantly from one another prior to the window over which the proxies are calibrated. This study attempts to quantify not only the skill with which we may expect to reconstruct the SAM but also to assess the contribution of regional bias in proxy selection and the impact of non-stationary proxy–SAM teleconnections on a resulting reconstruction. This is achieved using a pseudoproxy framework with output from the GFDL CM2.1 global climate model. Reconstructions derived from precipitation fields perform better, with 89 % of the reconstructions calibrated over a 61 year window able to reproduce at least 50 % of the inter-annual variance in the SAM, as opposed to just 25 % for surface air temperature (SAT)-derived reconstructions. Non-stationarity of proxy–SAM teleconnections, as defined here, plays a small role in reconstructions, but the range in reconstruction skill is not negligible. Reconstructions are most likely to be skilful when proxies are sourced from a geographically broad region with a network size of at least 70 proxies.
Free Cyanide Forms During Determination of Free Cyanide in Drinking Water

Easily detectable amounts of free cyanide (FCN) were formed when deionized water was treated like drinking water and preserved and tested for FCN. This occurred when either ascorbic acid or thiosulfate was used to dechlorinate, though higher FCN concentrations were observed with ascorbic acid. The amount of FCN observed was up to 50–60 µg/L but strongly depended on the concentration of ascorbic acid used. The amount of FCN observed was less dependent on the amount of thiosulfate used. The FCN was observed immediately after the samples were preserved, tended to increase—primarily during the first 24 h—and persisted for at least five days. This demonstrates the potential to get false positive FCN results on drinking water samples that a US public water system would be required to report in its annual Consumer Confidence Report. Since drinking water sampling, preservation, and testing is prescriptive, there are few available ways to avoid these false positives.
Improved big bang nucleosynthesis constraints on heavy neutral leptons

We constrain the lifetime of thermally produced heavy neutral leptons (HNLs) from big bang nucleosynthesis. We show that even a small fraction of mesons present in the primeval plasma leads to the overproduction of primordial helium-4. This constrains the lifetime of HNLs to be τ N < 0 . 02 s for masses above the mass of the pion (as compared to 0.1 s reported previously). In combination with accelerator searches, this allows us to put a new lower bound on the HNL masses and define the “ bottom line ” for HNL searches at the future Intensity Frontier experiments.
Display Ad Measurement Using Observational Data: A Reinforcement Learning Approach

This paper introduces an observational framework for measuring the eﬀects of display advertising. Causal measurement of display ad eﬀects using observational data presents a signiﬁcant challenge because of small eﬀect sizes and the selection biases induced by targeting. The proposed framework, derived from Markov Decision Processes, accounts for the diﬀerent sources of endogeneity by explicitly modeling the users’ browsing behavior and the advertiser’s decision making. Using the proposed framework, we develop a novel estimation method that recovers the incremental impact on outcomes attributable to (1) a display advertising campaign and (2) the individual impressions served. We validate the proposed method using a randomized controlled trial.
OTT_A_246430 4833..4842

Xiaoya Zhao* Jianfei Fu * Wanfen Tang Liangliang Yu Wenxia Xu 1Central Laboratory, Jinhua Hospital of Zhejiang University, Jinhua 321000, Zhejiang Province, People’s Republic of China; 2Department of Medical Oncology, Sir Run Run Shaw Hospital, Medical School of Zhejiang University, Hangzhou 310000, Zhejiang Province, People’s Republic of China; 3Department of Medical Oncology, Jinhua Hospital of Zhejiang University, Jinhua 321000, Zhejiang Province, People’s Republic of China; 4Department of Gastroenterology, Sir Run Run Shaw Hospital, Medical School of Zhejiang University, Hangzhou 310000, Zhejiang Province, People’s Republic of China
Demographic Profile & Correlation between Retinal Hemorrhages and Hematological Parameters in Leukemic Patients

Background: Leukemia is frequently associated with fundoscopic abnormalities. However, no organized effort has been made for analyzing leukemic retinopathy in our country. This study was done to observe the demographic profile and correlation between fundoscopic findings of retinal hemorrhages and hematological parameters in leukemic patients. Materials and Methods:The study was a hospitalbased descriptive cross-sectional study among 50 leukemic patients in Medicine and Oncology departments of Bangladesh Medical College and Hospital (BMCH) from May, 2020 to October, 2020. Fundoscopic examination was done which was reviewed by an ophthalmologist. Collected data was analyzed statistically by using SPSS-17 (Chicago, Illinois). Results: Among 50 leukemic patients, fundal lesions were detected in 32 patients (64%), retinal hemorrhages being the most common lesion (90.63%). Among hemorrhages, the majority (25, 86.2%) had flame shaped hemorrhage and 4(13.8%) had white centered hemorrhage. Hemorrhage was found in majority of acute lymphoblastic leukemia (ALL) and acute myeloid leukemia (AML) patients, 48.28% and 51.28% respectively. Hemorrhage was less frequently found in chronic lymphocytic leukemia (CLL) and chronic myeloid leukemia (CML) patients, 38.10% and 28.57% respectively. Hence hemorrhages were frequently seen in acute than chronic leukemia (p<0.001). Retinal hemorrhages were significantly associated with thrombocytopenia (p value<0.001). There was no statistically significant association between the fundal hemorrhages and high white cell count (p=0.25) or low hemoglobin level (p=0.08). Conclusion: This study has identified retinopathy occurring frequently in leukemic patients. Therefore, an adequate attention should be paid at fundoscopic evaluation while treating leukemic patients.
A prospective study on quality in endoscopic retrograde cholangiopancreatography (ERCP): trend in Italy from the REQUEST study

Abstract Background and study aims Endoscopic retrograde cholangiopancreatography (ERCP) is a complex procedure with a relatively high rate of adverse events. Data on training of operators and fulfillment of quality indicators in Italy are scarce. The goal of this study was to assess the overall quality of ERCP in Italy compared to international standards. Patients and methods This was a prospective, observational study from different Italian centers performing ERCP. Operators answered a questionnaire, then recorded data on ERCPs over a 1-to 3-month period. Results Nineteen Italian centers participated in the study. The most common concern of operators about training was the lack of structured programs. Seven/19 centers routinely used conscious sedation for ERCP. Forty-one experienced operators and 21 trainees performed 766 ERCPs: a successful deep biliary cannulation in native-papilla patients was achieved in 95.1 % of cases; the post-ERCP pancreatitis (PEP) rate was 5.4 % in native-papilla patients; cholangitis rate was 1.0 %; bleeding and perforation occurred in 2.7 % and 0.4 % of the patients, respectively. Conclusions This study revealed that, overall, ERCP is performed in the participating Italian centers meeting good quality standards, but structured training and sedation practice are still subpar. The bleeding and perforation rate slightly exceeded the American Society of Gastrointestinal Endoscopy indicator targets but they are comparable to the reported rates from other international surveys.
Investigating the antimicrobial activity of extract prepared by ultrasound against Escherichia coli isolated from poultry stool

Background: The aim of this study was to investigate the antimicrobial activity of Mentha piperita , Withania somnifera and Rosmarinus officinalis extract on antibiotic resistant Escherichia coli isolated from poultry stool in Zabol city. Materials & Methods: The extract of Mentha piperita, Rosmarinus officinalis and Withania somnifera was prepared by rotary machine. Escherichia coli strains were isolated from poultry stool samples. Minimum inhibitory concentration and minimum bactericidal concentration were determined by microdilution method. Results: The results of this study showed that Mentha piperita extract showed the highest inhibitory ratio compared to other extracts. The minimum inhibitory concentration was 3.1 ppm, with 5 strains inhibited at this concentration. Discussion: The results of this study could be an effective strategy for production and preparation of medicinal plants to help treating E. coli infections.
THE n-COLOR PARTITION FUNCTION AND SOME COUNTING THEOREMS

Recently, Merca and Schmidt found some decompositions for the partition function p(n) in terms of the classical Möbius function as well as Euler’s totient. In this paper, we define a counting function T r k (m) on the set of n-color partitions of m for given positive integers k, r and relate the function with the n-color partition function and other well-known arithmetic functions like the Möbius function, Liouville function, etc. and their divisor sums. Furthermore, we use a counting method of Erdös to obtain some counting theorems for n-color partitions that are analogous to those found by Andrews and Deutsch for the partition function.
Prevalence of Health Problems Targeted by the National School-Based Screening Program among Primary School Students in Saudi Arabia, 2019

The Saudi Ministry of Health (MOH) established a National School-Based Screening Program (NSBSP) for health screening of schoolchildren. Students from specific grades were systematically screened for several health problems, including obesity, visual and auditory problems, dental cavities, scoliosis, and attention-deficit/hyperactivity disorder (ADHD). This cross-sectional study aimed to determine the prevalence of these health problems among primary school students based on secondary data obtained from the NSBSP. We included 444,259 screened school children from the first and fourth grades of 50% of the selected schools (both private and public) across the Kingdom of Saudi Arabia (KSA) during the academic year 2018–2019. Among them, the most prevalent health problems identified were dental cavities (38.7%), eye refractory errors (10.9%), and overweight and obesity (10.5%); the less prevalent problems included ADHD (2.81%), auditory problems (0.6%), and scoliosis (0.48%). A greater prevalence of most health problems was observed in girls more than boys. The NSBSP successfully aided the detection of health conditions with high and low prevalence among primary school students in the KSA, and thus, the identification of health problems of specific concern. Implementation of effective school health services for the prevention, early detection, diagnosis, and treatment of these health problems are imperative.