Miracle-dz/UniFAR-FTUs huggingface dataset:
Effect of ESR, FSHB and PRLR Genes on Sperm Traits of Landrace and Yorkshire Boars in the Tropical Environmental Conditions of Vietnam

Background: Fertility traits in pigs made a restricted progress through traditional selection. Applying marker assisted selection could improve these traits. The aim of the study was to investigate the effects of candidate genes Estrogen Receptor (ESR), Follicle Stimulating Hormone Beta (FSHB) and Prolactin Receptor (PRLR) on sperm quality traits of Landrace and Yorkshire boars under tropical conditions in Northern Vietnam.Methods: A total of 6306 ejaculates from 140 boars (92 Landrace and 48 Yorkshire) were collected to estimate sperm ejaculate volume (VOL), spermatozoon motility (MO), sperm concentration (CO) and total number of spermatozoon in ejaculate (NT). Ear tissue samples were collected for genotype identification of SNP present in ESR, FSHB and PRLR genes using PCR-RFLP technique. A mixed model was used to test the effect of different genetic and non-genetic factors on the sperm quality traits.Result: The genotype frequencies of ESR, FSHB and PRLR were in Hardy-Weinberg equilibrium for each breed. Age of boars and month of the year had significant effect on all the sperm quality traits (P less than 0.01) while effect of breed was found to be non-significant on all the sperm quality trait. FSHB gene significantly (P less than 0.05) affected VOL, MO and CO. Boars with BB genotype showed positive effect on VOL but negative effect on MO and CO in comparison with AA genotype boars. ESR gene showed only effect on VOL while PRLR affected only MO. Boars with AA and AB genotypes of ESR gene had a significantly higher VOL than those with BB genotype (P less than 0.05). For PRLR gen, AB genotype was associated with higher MO than AA genotype (P less than 0.05). These results suggest a possibility of using the existing polymorphisms in ESR, FSHB and PRLR genes to improve some sperm traits of Landrace and Yorkshire boars.
Training Effectiveness on dasa Wisma Activist’s Knowledge Of Stunting and Prevention in The Working Area of Lebdosari Puskesmas in Semarang City

Malnutrition in Semarang City in 2015 was found as many as 39 cases with a prevalence according to BB / U over nutrition (4.36%), malnutrition (0.40%), under nutrition (3.54%) has increased. Whereas in 2014 there were 32 with the prevalence according to weight loss (4.75%), malnutrition (0.38%), malnutrition (2.73%) cases. This study aims to determine the effectiveness of training on knowledge dasa wisma activist regarding stunting in the work area of ​​the Lebdosari puskesmas in the city of Semarang. This type of research is a quantitative study with a quasi-experimental design with one group pretest-posttest without control. The population of this study is the activist dasa wisma in the work area of ​​Lebdosari Health Center in the city of Semarang totaling 30 people. The sampling technique used total sampling technique. Data collection used a questionnaire about stunting knowledge. Bivariate data analysis was performed using the Wilcoxon test. The results showed that the mean difference in knowledge 2 months after training and knowledge 1 month after training was 1.3. The Z value is -2.00 with a significance of 0.046, so it can be concluded that there is a significant difference in knowledge 2 months after training and knowledge 1 month after training. The recommendation of this research is for puskesmas to issue policies or programs for empowering cadres of dasa wisma in the form of health training, especially about stunting so that it can increase knowledge about stunting.
Biokinetic modeling and scale-up considerations for rotating biological contactors

Available growth kinetic models and a combined growth kinetic and mass transport model were applied to describe the performance of bench-scale rotating biological contactors (RBCs) in treating low-BOD, high-ammonia landfill leachate. The growth kinetic models could describe the observed organic carbon and ammonia removals individually, but as currently formulated they are not capable of describing the simultaneous removal of multiple substrates. Moreover, these models assume that substrate removal is not oxygen limited, an assumption that renders them of little use for prediction of substrate removal under high loading conditions where oxygen deficiency may occur. Such conditions occurred in the first stages of the bench-scale RBC units as has been observed at full-scale in various wastewater treatment applications
Biodurability of talc

Abstract Dissolution rates of a well-characterized sample of powdered talc were measured in solvents that mimic fluids found in the human lung. These experiments found that talc dissolution rates were the same for pH controlled aqueous solvents, phosphate buffered saline solution, and modified Gamble’s solutions. Variation of solvent chemistry, including the addition of organic chelators and proteins at intercellular fluid concentrations, does not markedly affect the measured dissolution rate of talc at 37 °C. The data further indicate that the dissolution mechanism for talc in aqueous solutions is independent of pH over the range of 2 to 8. The dissolution rate at 37 °C, determined by measuring the silicon release rate per unit surface area of talc in a mixed-flow reactor system, is 1.4 (±1.0) × 10-11 mol Si/m2·s. Application of a geometric shrinking particle model using this dissolution rate results in an estimated lifetime (upper limit) of approximately 8 years for a 1 μm talc particle under pulmonary conditions. Talc dissolves considerably faster than quartz, but slower than chrysotile and olivine in the body. These data can be used to place constraints on the role of particle dissolution in the disease models associated with airborne respirable mineral particles.
Use of The Bromocresol Purple Index (BCPI) in Measuring The Efficiency of Soybean Heat Treatment

A number of the most common methods used in assessing the efficiency of soybean heat treatment were compared in this study. All the methods proved to be useful in assessing the efficiency of heating soybean seeds and soybean products. However, considering the sensitivity, precision, time consumed, and the effectiveness of determination of the characteristics of the samples, the use of purple bromocresol index (BCPI) appears to be justified. The BCPI method turned out to be universal, allowing distinguishing unheated (BCPIBSM <70 mg.g -1), under-heated (70 mg.g -1 <BCPI BSM <130 mg.g -1), properly heated (BCPI BSM = 130-140 mg.g -1), and over-heated samples (BCPI BSM > 140 mg.g-1).
Evaporation residue cross section for the synthesis of superheavy element Fl in the reactions 242,244Pu+48Ca

Systematic calculations of the production cross section for the synthesis of superheavy elements 290,292 Fl using the reactions 48 Ca+ 242 Pu and 48 Ca+ 244 Pu are performed. We have studied the interaction barriers for these reactions against the distance between the centers of the projectile and target by taking Coulomb and proximity potential as the scattering potential. The fusion probability and survival probability of excited compound nucleus are calculated. At energies near and above the Coulomb barrier, capture, fusion and evaporation residue cross sections have been evaluated. The maximum value of 3n channel evaporation residue cross section for 48 Ca+ 242 Pu, 48 Ca+ 244 Pu reactions are 4.349 pb and 5.746 pb respectively. The highest yields for the 4n channel for these reactions are 4.006 pb and 9.079 pb respectively. Our calculated results are in good agreement with experimental data.
Awareness of glaucoma in the western region of Saudi Arabia

Aim: To evaluate the awareness about glaucoma among adults and its related health problems in Jeddah, Western region of Saudi Arabia and to assess the relationship between the awareness and knowledge about glaucoma across the socio-demographic characteristics. This will help to develop educational and screening programs of glaucoma which could help in early detection and diagnosis of the disease therefore reducing its sight threatening outcomes. Methods: A descriptive, cross-sectional study which included a sample of 608 adults in June 2019. Participants took part filling in the online multiple choice sociodemographic and glaucoma awareness questionnaire. Results: The mean age of the participants was 28.3 years ±11.4 with (59.2%) males and (40.8%) females. The majority of the respondents 70.9% were single and the majority had a bachelor's degree. Overall, 66.3% of the participants had knowledge about glaucoma, whereas 33.7% had no previous knowledge about glaucoma. Significant association between higher educational level and awareness of glaucoma was (P= 0.024). Females and age group (? 40) also showed significant associations with glaucoma awareness (P= <0.0001 and P= <0.0001 respectively). 58% of the aware group suffering from glaucoma and 36% have a family history or relatives diagnosed with glaucoma. High IOP and old age were the main risk factors chosen by the participants (74.2% and 72.5% respectively). The majority of the aware group reported that glaucoma can result in blindness and could be preventable. Conclusion: Assessing the glaucoma awareness in this study, the outcomes showed that majority had good knowledge of glaucoma. Larger surveys which include all cities of the country are suggested to assess the level of awareness and helps in establishing a proper educational and screening programs.
Contactin-1 Antibodies Link Autoimmune Neuropathies to Nephrotic Syndrome

Background: There is an established association between acquired inflammatory demyelinating neuropathies and nephrotic syndrome, but a common immunopathological mechanism has yet to be determined. Antibodies to known glomerular podocyte antigens occur in up to 90% of patients with nephrotic syndrome due to idiopathic membranous glomerulonephritis (MGN), the majority targeting the phospholipase A2 receptor (PLA2R). In patients with immune-mediated neuropathies, antibodies targeting molecules of the node of Ranvier, such as contactin-1 (CNTN1), are increasingly recognised. Methods: In this study, sera from 468 patients with suspected immune-mediated neuropathies, 295 with idiopathic MGN, and 210 disease controls, were tested for CNTN1 antibodies. Topographical binding patterns were determined using teased nerve fibres and live myelinated nerve co-cultures. CNTN1 expression in human kidney was characterised by immunohistochemistry, western blotting and PCR. Findings: A total of 16 patients with an immune-mediated neuropathy and MGN were seropositive for IgG4 anti-CNTN1 antibodies. The onset and resolution of both disorders had a close temporal relationship. The majority of cases were resistant to first-line therapies typically employed for inflammatory neuropathies, but achieved a good outcome with non-standard treatment. Four further patients with isolated MGN were also positive for the same antibodies at lower titres. CNTN1 protein was detected within glomerular deposits in biopsies from patients with CNTN1 antibodies, but not in healthy kidney or anti-PLA2R associated MGN. Interpretation: These data provide evidence that CNTN1 antibodies precipitate both autoimmune neuropathy and MGN. The temporal correlation of these disorders, as well as the presence of CNTN1 protein and antibodies in both peripheral nerve and diseased glomeruli, supports a common antibody-mediated pathological process, and defines a new antigenic target in MGN. CNTN1 antibodies have diagnostic and therapeutic relevance, and may additionally serve as a means of monitoring disease activity in both conditions. Funding Statement: Medical Research Council (MRC), GBS/CIDP Foundation International, MRC and Kidney Research UK. Declaration of Interests: SR runs a not-for-profit diagnostic testing service for nodal/paranodal antibodies. He has received a speaker’s honorarium and/or travel expenses from Fresenius Medical Care, Excemed, Alnylam and argenx. AR has received honoraria from Sarepta, Roche and Sanofi Aventis, is a member of MND Association Clinical Advisory Board, and was a member of NICE MND Guideline Development Group. ASC receives funding from NIHR University College London Hospitals Biomedical research centre. AM is a clinical fellow with grant reference number MR/P001777/1. SPi is was funded by a grant from the Karolinska Institutet during the course of the study. All other authors have nothing to declare. Ethics Approval Statement: Research Ethics Committee approval number 14/SC/0280
Urinary CXCL10 is Associated with Acute Kidney Injury and Sepsis, and Predicts Mortality in Critically Ill Children

Background: Acute kidney injury (AKI) biomarkers are often susceptible to confounding factors, limiting their utility as a specific biomarker, in the prediction of AKI, especially in heterogeneous population. The urinary CXC motif chemokine 10 (uCXCL10), as an inflammatory mediator, has been proposed to be a biomarker for AKI in a specific setting. Whether uCXCL10 is associated with AKI and predicts AKI in critically ill patients remains unclear. The aims of the study were to investigate clinical variables potentially associated with uCXCL10 levels and determine the associations of uCXCL10 with AKI, sepsis and PICU mortality in critically ill children, as well as its predictive values of aforementioned issues. Methods: Urinary CXCL10 levels were serially measured in a heterogeneous group of children during the first week after pediatric intensive care unit (PICU) admission. AKI diagnosis was based on the criteria of Kidney Disease: Improving Global Outcomes with serum creatinine and urine output. Sepsis was diagnosed according to surviving sepsis campaign international guidelines for children. Mortality was defined as all-cause death occurring during the PICU stay.Results: Among 342 critically ill children, 52 (15.2%) developed AKI during the first week after PICU admission, and 132 (38.6%) were diagnosed as sepsis and 30 (12.3%) died during PICU stay. Both the initial and peak values of uCXCL10 remained independently associated with AKI with adjusted odds ratios (AORs) of 1.791 (P = 0.010) and 2.002 (P = 0.002), sepsis with AORs of 1.679 (P = 0.003) and 1.752 (P = 0.002), septic AKI with AORs of 3.281 (P <0.001) and 3.172 (P <0.001), and PICU mortality with AORs of 2.779 (P = 0.001) and 3.965 (P <0.001), respectively. The AUCs of the initial uCXCL10 for predicting AKI, sepsis, septic AKI, and PICU mortality were 0.63 (0.53-0.72), 0.62 (0.56-0.68), 0.75 (0.64-0.87), and 0.77 (0.68-0.86), respectively. The AUCs for prediction by using peak uCXCL10 were as follows: AKI 0.65 (0.56-0.75), sepsis 0.63 (0.57-0.69), septic AKI 0.76 (0.65-0.87), and PICU mortality 0.84 (0.76-0.91). Conclusions: Urinary CXCL10 is independently associated with AKI and sepsis, and may be a potential indicator of septic AKI and PICU mortality in critically ill children.
Perceived Washback Effects of High-Stakes Test on the Teaching and Learning of Senior High School Economics

: This study investigated the perceived washback effects of high-stakes test, the West African Senior School Certificate Examination (WASSCE) on the teaching and learning of Economics. The study was a quantitative research which adopted the descriptive cross-sectional survey design. In all, 600 and 100 Senior High School (SHS) Economics students and teachers respectively, were sampled for the study. Data were collected through a 5-point Likert scale questionnaire ranging from strongly agree to strongly disagree. Inferential statistics (ANOVA and independent t-test) were used to analyse the data that were obtained. The findings of the study revealed that there was a statistically significant difference in the perceived washback effect of WASSCE on Economics students’ learning practices between SHS 1, SHS 2 and SHS 3 Economics students. Again, the study found a statistically significant difference in the perceived washback effect of WASSCE on Economics teachers’ classroom instructional practices between private and public SHS Economics teachers. Finally, the study revealed that there was no statistically significant difference in the perceived washback effects of WASSCE on Economics students’ learning practices between public and private SHSs Economics students. The study recommends that Heads of SHS institutions and Circuit Supervisors should pay particular attention to their supervisory roles, and ensure that teachers implement the entire broader content of the syllabus but not a selected few items. studied the washback effects of final examinations at on teaching and learning. The results of the study showed that the English examination had washback effect on teaching and learning, and this washback effect was more positive than negative. Also, Chou (2019) explored the effect of high-stakes examination on teaching and learning. The study collected data through the use of questionnaire and interview schedule from 311 Junior High School students and 12 teachers in Taiwan. In the study, a mixed method approach was used and the results revealed that the test influenced learning more than teaching. Contrary to the findings of Moradi, the study was not specific in respect of whether the washback effect was completely positive or negative.
Satellite-based Estimation of the Impacts of Summertime Wildfires on 
Particulate Matter Air Quality in United States

Abstract. Frequent and widespread wildfires in North Western United States and Canada has become the new normal during the northern hemisphere summer months, which degrades particulate matter air quality in the United States significantly. Using the mid-visible Multi Angle Implementation of Atmospheric Correction (MAIAC) satellite-derived Aerosol Optical Depth (AOD) with meteorological information from the European Centre for Medium-Range Weather Forecasts (ECMWF) and other ancillary data, we quantify the impact of these fires on fine particulate matter air quality (PM2.5) in the United States. We use a Geographically Weighted Regression method to estimate surface PM2.5 in the United States between low (2011) and high (2018) fire activity years. Our results indicate that smoke aerosols caused significant pollution changes over half of the United States. We estimate that nearly 29 states have increased PM2.5 during the fire active year and 15 of these states have PM2.5 concentrations more than 2 times than that of the inactive year. Furthermore, these fires increased daily mean surface PM2.5 concentrations in Washington and Oregon by 38 to 259 µgm−3 posing significant health risks especially to vulnerable populations. Our results also show that the GWR model can be successfully applied to PM2.5 estimations from wildfires thereby providing useful information for various applications including public health assessment.
Molecular and submolecular scale effects of comb‐copolymers on tri‐calcium silicate reactivity: Toward molecular design

The impact of organic compounds on the processing and reactivity of inorganic materials has been a source of inspiration for materials scientists for decades and continues to trigger novel and innovative applications in a broad range of disciplines. However, molecular design of such compounds to reach targeted properties remains challenging, particularly for reactive and multicomponent systems. This outstanding challenge is met here by combining a model cement, hosting different coupled reactions of dissolution, nucleation and growth, together with comb-copolymers that offer large and well-controlled variations of their molecular architecture. We show that silicate reactivity is affected by a combination of molecular and submolecular scale effects of these polymers. The first can be described by scaling laws from polymer physics, whereas the second involves specific chemical interactions. In particular, the ability of these polymers to hinder dissolution appears to be crucial, something for which strong experimental evidence is provided.
RESEARCH-ORIENTED TEACHING IN HOSPITALITY AND TOURISM MARKETING: CRITICAL REFLECTIONS ON PRACTICE

The article considers crucially the introduction of research approach and research training in teaching business disciplines. The development of research culture at the University and its practical and social significance among students and University employees is becoming an essential component of well-developed modern universities. Research-oriented learning strategies are considered very important not only for research universities, but also for business universities in Kazakhstan. This article provides critical reflections on professional experience of using research-oriented teaching strategies in business related disciplines and describes the process of implementation of new teaching methodologies in higher education. It presents the preliminary results of the part of a longitudinal observational study on students’ performance and professional development affected by competencybased research-focused learning on the example of «Services Marketing» course. Quantitative as well as observational data have been collected within the prolonged periods of time including 3 years of teaching experience. A comparative analysis of academic performance showed that average grades for research-based student assignments had been lower than grades for traditional academic tasks, while overall professional competences of students had been significantly improved as a result of researchoriented teaching. The study contributes to the body of knowledge describing the state of transitional educational systems in developing countries and fills a contextual gap by addressing important methodological issues of higher education in Kazakhstan. Key words: research-oriented teaching, research methodology, competency-based learning, hospitality and tourism.
Does Managerial Ownership Moderate the Relationship between Corporate Social Responsibility Disclosure and Tax Aggressiveness?

Companies' disclosure is an important thing to do because it is one of the corporate governance concepts. The purpose of this study is first to investigate the influence of corporate social responsibility disclosure on corporate tax aggressiveness. Also, to prove the influence of managerial ownership as a moderating variable in the relationship between corporate social responsibility and tax aggressiveness. This study uses secondary data, namely financial statements and annual reports that have been published by companies on the Indonesia Stock Exchange and the company's website. This study's population are mining companies listed on the Indonesia Stock Exchange during the 2014-2018 period. Using the purposive sampling method, the total sample of this study is 30 data from 39 companies. Data were analyzed by descriptive analysis and multiple regression analysis. The results of this study indicate that Corporate social responsibility disclosure affects tax aggressiveness. And managerial ownership as a moderating variable affects the relationship between corporate social responsibility disclosure and tax aggressiveness. It is suggested that companies must pay attention to the CSR disclosure and ownership structure and their relationship with tax aggressiveness.