Miracle-dz/UniFAR-FTUs huggingface dataset:
The Child Behavior Checklist and related forms for assessing behavioral/emotional problems and competencies.

1. Thomas M. Achenbach, PhD* 2. Thomas M. Ruffle, MD† 1. 2. *Departments of Psychiatry and Psychology, University of Vermont, Burlington, VT. 3. 4. †Vermont Child Development Clinic, Burlington, VT. After completing this article, readers should be able to: 1. List the types of behavioral and emotional problems that primary care physicians who work with children must address. 2. Describe the data required from parents, children, teachers, and child care practitioners for assessment of behavioral and emotional problems. 3. Describe systems of questionnaires that can be used for obtaining standardized assessment data. Primary care physicians who work with children must deal with a great variety of behavioral and emotional problems. The system described in this article provides low-cost, standardized assessment and documentation of such problems and requires little effort by the physician. Primary care physicians are under increasing pressure to obtain standardized documentation for the conditions they encounter. The most obvious pressures stem from managed care. Among the most frequently imposed expectations of primary care physicians are to: Be gatekeepers for most forms of care needed by patients. Offer increasingly diverse services to more patients while limiting the time spent with each patient. Provide extensive documentation for assessments of patients and for treatment and referral. To fulfill these expectations, physicians need cost-effective procedures for obtaining, using, and transmitting information about patients. Children’s behavioral and emotional problems pose special challenges for meeting such managed care requirements. Certain types of behavioral problems, such as those ascribed to attention deficit hyperactivity disorder (ADHD), are widely publicized as candidates for medical management. Concerned parents, therefore, may request that pediatricians and family practitioners evaluate their children for ADHD. To assess ADHD and other behavioral and emotional problems, physicians need information from people who see children in their everyday contexts. Parents and parent-surrogates are the primary sources of such information for most children. Older children can contribute useful information about their own functioning. Teachers are especially important sources of information when children’s functioning in school is relevant, such as …
Effects of encapsulated green tea and Guarana extracts containing a mixture of epigallocatechin-3-gallate and caffeine on 24 h energy expenditure and fat oxidation in men

It has been reported that green tea has a thermogenic effect, due to its caffeine content and probably also to the catechin, epigallocatechin-3-gallate (EGCG). The main aim of the present study was to compare the effect of a mixture of green tea and Guarana extracts containing a fixed dose of caffeine and variable doses of EGCG on 24 h energy expenditure and fat oxidation. Fourteen subjects took part to this randomized, placebo-controlled, double-blind, cross-over study. Each subject was tested five times in a metabolic chamber to measure 24 h energy expenditure, substrate oxidation and blood pressure. During each stay, the subjects ingested a capsule of placebo or capsules containing 200 mg caffeine and a variable dose of EGCG (90, 200, 300 or 400 mg) three times daily, 30 min before standardized meals. Twenty-four hour energy expenditure increased significantly by about 750 kJ with all EGCG–caffeine mixtures compared with placebo. No effect of the EGCG–caffeine mixture was observed for lipid oxidation. Systolic and diastolic blood pressure increased by about 7 and 5 mmHg, respectively, with the EGCG–caffeine mixtures compared with placebo. This increase was significant only for 24 h diastolic blood pressure. The main finding of the study was the increase in 24 h energy expenditure with the EGCG–caffeine mixtures. However, this increase was similar with all doses of EGCG in the mixtures.
Private analysis of graph structure

We present efficient algorithms for releasing useful statistics about graph data while providing rigorous privacy guarantees. Our algorithms work on data sets that consist of relationships between individuals, such as social ties or email communication. The algorithms satisfy edge differential privacy, which essentially requires that the presence or absence of any particular relationship be hidden. Our algorithms output approximate answers to subgraph counting queries. Given a query graph H, e.g., a triangle, k-star or k-triangle, the goal is to return the number of edge-induced isomorphic copies of H in the input graph. The special case of triangles was considered by Nissim, Raskhodnikova and Smith (STOC 2007), and a more general investigation of arbitrary query graphs was initiated by Rastogi, Hay, Miklau and Suciu (PODS 2009). We extend the approach of [NRS] to a new class of statistics, namely, k-star queries. We also give algorithms for k-triangle queries using a different approach, based on the higher-order local sensitivity. For the specific graph statistics we consider (i.e., k-stars and k-triangles), we significantly improve on the work of [RHMS]: our algorithms satisfy a stronger notion of privacy, which does not rely on the adversary having a particular prior distribution on the data, and add less noise to the answers before releasing them. We evaluate the accuracy of our algorithms both theoretically and empirically, using a variety of real and synthetic data sets. We give explicit, simple conditions under which these algorithms add a small amount of noise. We also provide the average-case analysis in the Erdős-Rényi-Gilbert G(n, p) random graph model. Finally, we give hardness results indicating that the approach NRS used for triangles cannot easily be extended to k-triangles (and hence justifying our development of a new algorithmic approach).
Malakoplakia of the Prostate as a Mimicker of Prostate Cancer on Prostate Health Index and Magnetic Resonance Imaging–Fusion Prostate Biopsy: A Case Report

Abstract Background: Isolated malakoplakia of the prostate is a rare inflammatory condition that has been clinically mistaken for prostatic malignancies. The development of Prostate Imaging Reporting and Data System (PI-RADS) classifications, and Prostate Health Index (PHI) has led to more accurate diagnosis of clinically significant disease and stratification of patients that may be at risk of prostate cancer. Case Presentation: We present a case of a 75-year-old male who was on follow-up with our hospital for elevated prostate specific antigen (PSA). He was admitted for an episode of urosepsis, which was treated with antibiotics and subsequently underwent further workup and was found to have a raised PHI, as well as a high PI-RADS classification and was later found to have malakoplakia based on histology of prostate tissue obtained during targeted magnetic resonance imaging (MRI)-guided fusion prostate biopsy. Conclusion: To our understanding, this is the first case where a prostate lesion has been labeled as a PI-RADS 5 lesion, with elevated PHI that has subsequently been proven histologically to be malakoplakia. An important possible confounder is the interval between the MRI and the episode of urosepsis and it is well known that urosepsis can affect the PSA and MRI result. We present this case to highlight the potential for a false diagnosis of prostate cancer, in spite of laboratory and radiological findings.
Integration of Real-Time Speech Processing Technologies for Online Gaming

This work demonstrates an application of different real-time speech technologies, exploited in an online gaming scenario. The game developed for this purpose is inspired by the famous television based quiz-game show, “Who wants to be a millionaire”, in which multiple-choice questions of increasing difficulty are asked to the participant. Text-to-speech synthesis is used to read out the questions and the possible answers to the user, while an automatic speech recognition engine is exploited to get input from the player, in order to proceed through the game. The speech data is recorded from the user with the help of a real-time voice activity detector to select speech segments from the input audio data. The developed Java application allows an automatic insertion of new multiple-choice questions, of different complexity, which could then be selected during the game.
Linear lower bounds on real-world implementations of concurrent objects

This paper proves /spl Omega/(n) lower bounds on the time to perform a single instance of an operation in any implementation of a large class of data structures shared by n processes. For standard data structures such as counters, stacks, and queues, the bound is tight. The implementations considered may apply any deterministic primitives to a base object. No bounds are assumed on either the number of base objects or their size. Time is measured as the number of steps a process performs on base objects and the number of stalls it incurs as a result of contention with other processes.
Piezoelectric Harvesters and MEMS Technology: Fabrication, Modeling and Measurements

Piezoelectric converters designed for harvesting energy from mechanical vibrations have been fabricated by micromachining technologies. The manufactured piezoelectric energy harvesters have been characterized by applying a sinusoidal oscillation as mechanical input and by using a simple resistive load to measure the output power of the system. A maximum output power of 40 muW has been measured for an input vibration having a frequency of 1.8 kHz and an amplitude of 180 nm. A model aimed at estimating the output power of the fabricated piezoelectric structures has been developed and theoretical estimations have been compared with experimental results.
Construction and behavior of circularly permuted and telocentric chromosomes in Saccharomyces cerevisiae

We developed techniques that allow us to construct novel variants of Saccharomyces cerevisiae chromosomes. These modified chromosomes have precisely determined structures. A metacentric derivative of chromosome III which lacks the telomere-associated X and Y' elements, which are found at the telomeres of most yeast chromosomes, behaves normally in both mitosis and meiosis. We made a circularly permuted telocentric version of yeast chromosome III whose closest telomere was 33 kilobases from the centromere. This telocentric chromosome was lost at a frequency of 1.6 X 10(-5) per cell compared with a frequency of 4.0 X 10(-6) for the natural metacentric version of chromosome III. An extremely telocentric chromosome whose closet telomere was only 3.5 kilobases from the centromere was lost at a frequency of 6.0 X 10(-5). The mitotic stability of telocentric chromosomes shows that the very high frequency of nondisjunction observed for short linear artificial chromosomes is not due to inadequate centromere-telomere separation.
Playlist Generation using Start and End Songs

A new algorithm for automatic generation of playlists with an inherent sequential order is presented. Based on a start and end song it creates a smooth transition allowing users to discover new songs in a music collection. The approach is based on audio similarity and does not require any kind of meta data. It is evaluated using both objective genre labels and subjective listening tests. Our approach allows users of the website of a public radio station to create their own digital “mixtapes” online.
Semantically-supported team building in a KDD virtual environment

Team building plays a crucial role in many collaborative projects. The use of semantic technologies and tools, like ontologies and metadata management proved to be a powerful approach to organize people competencies and support the formation of teams. Although Knowledge Discovery in Databases (KDD) has inherent collaborative characteristics, team building in this domain has not been the subject of extensive work yet. In this paper we start filling this gap by presenting TeamOnto, an ontology for the representation of project teams. TeamOnto is part of a wide, modular and integrated Knowledge Base about KDD projects, of which we briefly illustrate some modules, showing their use to support team building in the KDD domain.
Dynamic Doppler evaluation of the radial and ulnar arteries in patients with carpal tunnel syndrome.

OBJECTIVE The objective of our study was to evaluate the blood flow characteristics of the radial and ulnar arteries of the hands of patients with carpal tunnel syndrome (CTS) either in the neutral position or in provocative positions using color Doppler imaging. SUBJECTS AND METHODS Subjects with relevant complaints of CTS and positive Tinel sign and/or Phalen maneuver were recruited. Nerve conduction studies were performed to confirm the diagnosis of CTS. Forty-four hands of 22 patients with CTS (bilateral involvement) and 24 hands of 12 healthy volunteers were included in the study. Pulsed and color Doppler evaluations with the hands in the neutral, Phalen, and reverse Phalen positions were performed of the radial and ulnar arteries using a 5-13-MHZ linear-array transducer (Logiq 9). RESULTS All of the CTS patients and control subjects were women; their mean ages were 50.77 ± 7.69 (SD) and 46.42 ± 4.32 years, respectively. When hands were evaluated in the neutral position, the flow volume, peak systolic velocity, end-diastolic velocity, and diameter values of both the radial and ulnar arteries were significantly greater in patients with CTS than in control subjects (all p < 0.05). When compared with the measurements obtained with hands at the neutral position, the decreases in the amount of blood flow during the Phalen and reverse Phalen maneuvers were significantly greater in the CTS group than the control group. The amount of blood flow decrease was not correlated with the disease duration. CONCLUSION Blood flow in the hands of CTS patients differs from that of healthy individuals both at rest and during certain hand movements. Future studies, also with simultaneous monitoring of sympathetic innervation, could be beneficial to confirm the association between blood flow and the sympathetic nerves of the hand.
Neonatal idiopathic primary hypoparathyroidism: A rare cause of neonatal seizures

Etiology of neonatal seizures (NNS) is diverse and hypocalcemia is one of the treatable causes. Neonatal hypocalcemia (NHC) due to congenital hypoparathyroidism, either permanent or transient, is extremely rare. Its biochemical abnormalities include hypocalcemia, hyperphosphatemia and low levels of intact parathyroid hormone (PTH). Isolated congenital hypoparathyroidism in which deficiency of PTH has no association with maternal, syndromic or endocrine defects is a very rare entity. We are reporting a case of a newborn who presented with seizures on the 5th day of life and later on investigations revealed hypocalcaemia due to isolated congenital hypoparathyroidism.
An investigation of body fat accrual in an ethnically diverse cohort of British Columbian children and youth: patterns, obesity classification, and determinants

Obesity during childhood and adolescence is a serious public health concern in Canada and globally. Obesity is a complex disease with genetic, environmental, social, and behavioural determinants. However, our understanding of obesity and its development is limited by a reliance on proxy measurements of adiposity such as body mass index (BMI) and cross-sectional study designs that limit our ability to assess temporality. In this dissertation, I present the first set of body fat percent (BF%) accrual and velocity percentile curves for Canadian children and youth, investigate the relationship between BMIand BF%-based definitions of obesity, and examine the longitudinal influence of sedentary time, moderate-to-vigorous physical activity (MVPA) and caloric intake on the development of BF%. My analyses are based on the UBC Healthy Bones III Study (HBSIII), a mixed longitudinal study of boys and girls aged 8-12 years at baseline, measured between 1999 and 2012. In HBSIII, adiposity was measured directly as BF% from total body dual energy x-ray absorptiometry (DXA) scans and MVPA and sedentary time were measured objectively using accelerometers. For the first study in my dissertation, I used generalized additive models for location scale and shape (GAMLSS) to develop sexand ethnic-specific BF% accrual and velocity percentile curves. I present separate curves for Asian and Caucasian boys and girls aged 9-19 years at the 3, 10, 25, 50, 75, 95, and 97 centiles. In this descriptive study, I found materially different shaped BF% percentile curves for Asian and Caucasian girls but not for boys. iv Second, I examined the relationship between BMIand BF%-based definitions of obesity for Asian and Caucasian boys and girls aged 9-19 years. I used multivariable regression models, sensitivity and specificity analysis, receiver operating characteristic (ROC) curves, and Youden’s Index to explore this relationship. I found that BMI identified <50% of those classified with obesity based on BF%, and that classification performance of BMI differed significantly by age and sex subgroups for Asian and Caucasians. In my third analysis, I explored the longitudinal relationship between BF% and sedentary time, MVPA, and caloric intake as boys and girls mature. I fit polynomial multilevel models using MO (years from age at peak height velocity, APHV) as the time variable. Rate of change in BF% across maturity differed between boys and girls and differences in MVPA, sedentary time, and caloric intake between individuals influenced BF% at APHV (MO=0) and rate of change in BF% across maturity. Together, these studies advance our understanding of how body fat accrues as children and youth mature, and highlight the heterogeneity in predictors of adiposity and adiposity measurement accuracy across age, sex, and ethnic groups.
Hybrid Named Entity Recognition System for South and South East Asian Languages

This paper is submitted for the contest NERSSEAL-2008. Building a statistical based Named entity Recognition (NER) system requires huge data set. A rule based system needs linguistic analysis to formulate rules. Enriching the language specific rules can give better results than the statistical methods of named entity recognition. A Hybrid model proved to be better in identifying Named Entities (NE) in Indian Language where the task of identifying named entities is far more complicated compared to English because of variation in the lexical and grammatical features of Indian languages .
Genetic Variability of Aspergillus flavus Isolates from a Mississippi Corn Field

A nontoxigenic Aspergillus flavus strain, K49, is currently being tested as a biological control agent in corn fields in the Mississippi Delta. However, little is known about the overall genetic diversity of A. flavus from year to year in corn fields and specifically in Mississippi. Our objective was to assess the genetic variability of A. flavus isolates from different seasons, inoculum sources, and years, from a no-till corn field. Of the 175 A. flavus isolates examined, 74 and 97 had the typical norB-cypA type I (1.5 kb) and type II (1.0 kb) deletion patterns, respectively. Variability in the sequence of the omtA gene of the majority of the field isolates (n = 118) was compared to strain K49. High levels of haplotypic diversity (24 omtA haplotypes; Hd = 0.61 ± 0.04) were found. Among the 24 haplotypes, two were predominant, H1 (n = 71), which consists of mostly toxigenic isolates, and H49 (n = 18), which consists of mostly atoxigenic isolates including K49. Toxigenic isolates were prevalent (60%) in this natural population. Nonetheless, about 15% of the population likely shared the same ancestral origin with K49. This study provides valuable information on the diversity of A. flavus. This knowledge can be further used to develop additional biological control strains.
Diffusion-weighted MRI in the body: applications and challenges in oncology.

OBJECTIVE In this article, we present the basic principles of diffusion-weighted imaging (DWI) that can aid radiologists in the qualitative and quantitative interpretation of DW images. However, a detailed discussion of the physics of DWI is beyond the scope of this article. A short discussion ensues on the technical aspects of performing DWI in the body. The emerging applications of DWI for tumor detection, tumor characterization, distinguishing tumor tissue from nontumor tissue, and monitoring and predicting treatment response are highlighted. The challenges to widespread adoption of the technique for cancer imaging in the body are discussed. CONCLUSION DWI derives its image contrast from differences in the motion of water molecules between tissues. Such imaging can be performed quickly without the need for the administration of exogenous contrast medium. The technique yields qualitative and quantitative information that reflects changes at a cellular level and provides unique insights about tumor cellularity and the integrity of cell membranes. Recent advances enable the technique to be widely applied for tumor evaluation in the abdomen and pelvis and have led to the development of whole-body DWI.
Contribution of glutathione S-transferase gene polymorphisms to development of skin cancer.

BACKGROUND Glutathione S-transferase (GST) family genes are of vital importance in maintaining cellular defence systems, protecting cells against the toxic effects of reactive oxygen produced during the synthesis of melanin, and detoxifying environmental mutagens and chemical or synthetic drugs. As no previous meta-analyses have examined the association of polymorphisms at GSTT1, GSTP1 Ile105Val with skin cancer risk and independently published studies have produced inconsistent conclusions, we were promoted to estimate the associations in the largest study to date. METHODS Computer-assisted searches were carried out to systematically identify the studies of GST polymorphisms and skin cancer. The eligibility of studies was evaluated following the requirements of inclusion criteria. Risk of skin cancers (OR and 95% CI) was assessed with the fixed or random effects meta-analysis. MAJOR FINDINGS The fixed effects meta-analysis of 15 studies suggested no overall association between GSTT1 null and skin cancer. Nor was there a significant association in any subgroup. However, in the stratified analysis by histologic type for GSTP1 Ile105Val, we found 1.56 times higher risk of malignant melanoma (MM) among people with the 105-Val/Val genotype (Val/Val vs. Ile/Ile: OR = 1.56, 95% CI = 1.05-2.32, pheterogeneity = 0.584). CONCLUSIONS These statistical data demonstrate that Ile105Val polymorphism of the GSTP1 gene may have genetic contribution to the development of skin cancer, MM in particular.