Miracle-dz/UniFAR-FTUs huggingface dataset:
Febrile Seizure Causes Deficit in Social Novelty, Gliosis, and Proinflammatory Cytokine Response in the Hippocampal CA2 Region in Rats

Febrile seizure (FS), which occurs as a response to fever, is the most common seizure that occurs in infants and young children. FS is usually accompanied by diverse neuropsychiatric symptoms, including impaired social behaviors; however, research on neuropsychiatric disorders and hippocampal inflammatory changes following febrile seizure occurrences is very limited. Here, we provide evidence linking FS occurrence with ASD pathogenesis in rats. We developed an FS juvenile rats model and found ASD-like abnormal behaviors including deficits in social novelty, repetitive behaviors, and hyperlocomotion. In addition, FS model juvenile rats showed enhanced levels of gliosis and inflammation in the hippocampal CA2 region and cerebellum. Furthermore, abnormal levels of social and repetitive behaviors persisted in adults FS model rats. These findings suggest that the inflammatory response triggered by febrile seizures in young children could potentially serve as a mediator of social cognitive impairments.
Gediz Grabeninin Doğu Kesimindeki Güncel Tektonik Hareketlerin GPS Ve Ps-InSAR Yöntemleri Kullanılarak Belirlenmesi; İlk Sonuçlar

Bircok uygarligin uzerinde gelistigi Bati Anadolu, tarihsel donemlerde de bircok yikici depremlerin etkisinde kalmistir. Calisma bolgesini kapsayan alanda tarihsel donemde olusmus 13 dolayinda deprem bilinmektedir. Bu tarihsel depremlerin buyuk bir cogunlugu Gediz grabeni cevresinde yogunlasmaktadir. Gediz Grabenindeki tarihsel deprem aktivitesi incelendiginde, Grabenin bati ucundaki bolgede MO. 17 ve M.S. 1592, 1850, 1862 yillarinda, Grabenin dogu ucundaki bolgede ise M.S. 60 ve 494 yillarinda siddeti VIII’den buyuk depremlerin meydana geldigi bilinmektedir. Ayrica bu belirtilen tarihlerden sonra ise, Grabenin dogu ucunda M=6.5 buyuklugundeki 28 Mart 1969 Alasehir Depremi’nin oldugu bilinmektedir. Bu depremin grabenin guney ana sinir fayi boyunca olustugu kabul edilmektedir [1]. Deprem sirasinda Gediz grabenin Alasehir-Sarigol arasindaki kesiminde 36 km uzunlugunda olusan yuzey kirigi ve bolgede, depremden sonra nasil bir deformasyonun devam ettigi bilinmemektedir. DAP-C-13-07 ve TUBITAK 113Y526 numarali projeler kapsaminda yurutulen calismada, iki farkli uzaysal jeodezik teknoloji olan SAR (Yapay Acikli Radar) interferometrisi ve GPS (Kuresel Konumlandirma Sistemi) kullanilarak Alasehir-Sarigol civarindaki guncel deformasyonlarin izlenmesi amaclanmistir. Her iki yontem de yersel deformasyonlarin belirlenmesinde ve izlenmesinde gittikce artan oranda yaygin olarak kullanilmaktadir. Iki yontem ile elde edilecek sonuclarin birbirlerine gore ustunlukleri bulunmaktadir. GPS ile yapilan cm-alti duyarlikta noktasal bazda olcmeler, yersel deformasyonun yatay bilesenine duyarliyken (dusey hata yatay hatalarin yaklasik iki katidir), InSAR ile yapilan cm-duzeyindeki alansal olcumler dusey dogrultudaki yer degisimlerin belirlenmesinde etkili olmaktadir. Bu calismada, her iki teknolojinin ustunlukleri birlikte kullanilarak, yersel uzun donem deformasyonlarin belirlenmesine yonelik calismalarin yapilmasi hedeflenmistir.
Theoretical and Experimental Studies of Dendritic Metacommunities

Keywords: dendritic ecological networks ; riverine ecosystems ; metacommunity ; community assembly ; directional dispersal ; functional diversity ; species-interactions ; experimental microcosms ; optimal channel networks ; stability ; stochastic noise ; voter model ; zero-sum game These Ecole polytechnique federale de Lausanne EPFL, n° 5955 (2013)Programme doctoral en genie civil et environnementFaculte de l'environnement naturel, architectural et construitInstitut d'ingenierie de l'environnementLaboratoire d'ecohydrologieJury: R. Bernier-Latmani (presidente), J.G. Hering, M. Holyoak, A. Maritan Public defense: 2013-12-3 Reference doi:10.5075/epfl-thesis-5955Print copy in library catalog Record created on 2013-11-27, modified on 2016-08-09
Systemic and local inflammatory response after implantation of biomaterial in critical bone injuries

ABSTRACT Purpose: To evaluate inflammatory response in critical bone injuries after implantation of the biomaterial composed of hydroxyapatite (HA)/poly (lactic-coglycolic acid) (PLGA)/BLEED. Methods: Forty-eight male Wistar rats (280 ± 20 grams) were divided into two groups: control group (CG), in which the animals do not receive any type of treatment; and biomaterial group (BG), in which the animals received the HA/PLGA/BLEED scaffold. Critical bone injury was induced in the medial region of the skull calotte with the aid of a trephine drill 8 mm in diameter. The biomaterial was implanted in the form of 1.5-mm thick scaffolds. Serum and calotte were collected at one, three and seven days. Results: Biomaterial had a significant effect on the morphological structure of the bone, accelerating osteoblast activation within three days, without causing exacerbated systemic inflammation. In addition, quantitative real-time polymerase chain reaction (qRT-PCR) analysis showed that BG induced upregulation of osteogenic genes such as runt-related transcription factor 2, and stimulated genes of inflammatory pathways such as tumor necrosis factor-α, on the first day without overexpressing genes related to bone matrix degradation, such as tissue inhibitor of metalloproteinases-1 and matrix metalloproteinase-9. Conclusions: The HA/PLGA/BLEED® association can be used as a bone graft to aid bone repair, as it is capable of modulating expression of important genes at this stage of the repair process.
Competitive Advantage as a Mediating Product Innovation and Social Media for
 The MarketingPerformance of Micro Small Medium Economics (MSMES) In
 Surabaya

The majority of MSMEs in Surabaya, in practice, lack product innovation and use social media ads features to expand their market share. Innovations carried out by MSMEs have an important role in their sustainability in facing difficult situations and positions, for this reason, this study aims to examine the effect of product innovation and social media on marketing performance mediated by competitive advantage. The population of this research is MSMEs in Surabaya with a sample of 117 MSMEs, the sampling technique is non-probability sampling with purposive sampling the criteria are MSMEs that use social media ads and have more than 3 product variants. The analytical technique used is partial least square (PLS). The test results show that the hypothesis that explains product innovation and social media has a direct effect on marketing performance is acceptable. The hypothesis that explains the product and social media innovation on marketing performance mediated by competitive advantage are acceptable. The hypothesis that explains the product and social media innovation on competitive advantage are acceptable. These results show the importance of research on product innovation and social media that can boost the competitive advantage to expand market share
Palaeohydrological records derived from testate amoebae analysis from peatlands in northern England: within-site variability, between-site comparability and palaeoclimatic implications

Testate amoebae analysis was undertaken on eight cores from three mires within a restricted geographical area of northern England. This was used to assess, first, the amount of autogenically produced variability in palaeohydrological records from ombrotrophic mires, and, second, to determine whether a palaeoclimatic signal can be derived from testate amoebae analysis from peatlands. Past mean annual water tables were reconstructed by calibrating the testate amoebae record with an existing transfer function. There is a good degree of replicability between the water table reconstructions for the upper peats within each site (especially since cal. AD 600) and the magnitude and timing of most changes are similar. The results show that autogenic factors have a relatively minor control on palaeohydrological records from ombrotrophic peatlands, even for marginal locations where these effects should be greatest. Records from the centres of peatlands are compared to assess the replicability of hydrological changes between the sites to determine which of these changes are attributable to climate. The major fluctuations are well replicated in all central cores, especially for the last 2000 years, suggesting that these shifts are climatically forced and that there is an increasing climatic influence through time, even at the valley mire site. Comparisons with other proxy climatic records suggest that mire surface wetness changes occurred in concert across a broad region of northern England and southern Scotland during at least the last 2000 years.
Isolation and Diagnosis of Some Isolated Bacterial Types of Psoriasis Patients and Measurement of Some Immunological Parameters Such as Il-17 And Complements C3 and C4

aureus, 33.3% of the 60 bacterial isolates were isolated, it isolated 18 isolates of Staph epidermidis with 30% of the total isolates and Staphylococcus hominas isolated by 15%, gram-negative isolates included 13.3% of P. aeruginosa and five isolates of E. coli (8.3%), some immune markers were compared between a group of psoriasis patients and a healthy (control) group, the estimated C3 supplement level for patients is 265.1 ± 215.77, while the rate for healthy people is 652.18 ± 102.3, it is noted that this indicator is higher in patients with psoriasis compared to healthy people, it also indicates that the estimated C4 supplement level for patients is 392.92 ± 63.7, while the rate for healthy people is 167.94 ± 38.7. It is noted that this indicator is higher in patients with psoriasis compared to healthy people, the IL-17 level of interleukin was 765.29 ± 85.4, while the rate for healthy people is 212.37 ± 39.6. It is noted that this indicator is higher in patients with psoriasis compared to healthy people, the results also showed significant differences between the levels of immune indicators between patients and healthy people at a probability level (p value = 0.05).
The effectiveness of structured sport and exercise interventions in enhancing the mental health of adolescents with mild to moderate mental health problems: a systematic review

Between 10% and 20% of adolescents globally have a diagnosed mental health disorder and a big proportion of individuals experience their ﬁ rst mental health problem during adolescence. However, limited research has investigated how an adult-led structured sport and exercise intervention can be used to support adolescents with mild to moderate mental health problems. A systematic review of the literature ( ﬁ ve databases) was performed. Included studies (qualitative and quantitative) explored structured sport and exercise interventions aiming to help adolescents (aged 10 – 19 years) experiencing mild to moderate mental health problems. From 3506 studies screened, nine met the inclusion criteria (RCT = 6 and non-RCT = 3) following the PICOS, TIDieR frameworks and assessing quality of studies using the Mixed Methods Appraisal Tool. Activities included a group-based circuit training, high-intensity interval training, dance, group-based aerobic exercise, mindfulness-based Tai Chi Chuan and rugby. All included studies showed clinical improvements in adolescents ’ anxiety or depression (anxiety, n = 5 and depression, n = 7). There is evidence that structured sport and exercise interventions can support adolescents with mild to moderate mental health problems. However, more research is needed to understand the mechanisms of how these outcomes are achieved, speci ﬁ cally using well-designed interventions tailored to speci ﬁ c exercises/sports, populations, and mental health outcomes.
Northern hemispheric winter warming pattern after tropical volcanic eruptions: Sensitivity to the ozone climatology

An important key for the understanding of the dynamic response to large tropical volcanic eruptions is the warming of the tropical lower stratosphere and the concomitant intensification of the polar vortices. Although this mechanism is reproduced by most general circulation models today, most models still fail in producing an appropriate winter warming pattern in the Northern Hemisphere. In this study ensemble sensitivity experiments were carried out with a coupled atmosphere‐ocean model to assess the influence of different ozone climatologies on the atmospheric dynamics and in particular on the northern hemispheric winter warming. The ensemble experiments were perturbed by a single Tambora‐like eruption. Larger meridional gradients in the lower stratospheric ozone favor the coupling of zonal wind anomalies between the stratosphere and the troposphere after the eruption. The associated sea level pressure, temperature, and precipitation patterns are more pronounced and the northern hemispheric winter warming is highly significant. Conversely, weaker meridional ozone gradients lead to a weaker response of the winter warming and the associated patterns. The differences in the number of stratosphere‐troposphere coupling events between the ensembles experiments indicate a nonlinear response behavior of the dynamics with respect to the ozone and the volcanic forcing.
Study of Corneal Curvature with Pterygium Morphology in Tertiary Care Center in Central India

Purpose: To evaluate the correlation between corneal astigmatism and pterygium morphology by anterior segment optical coherence tomography. Methods: Patients diagnosed with unilateral pterygium were included in this prospective crosssectional study. A thorough history was taken and each patient underwent detailed ocular examination including demographic data, subjective refraction with best corrected visual acuity using a Snellen’s chart, anterior and posterior segment examination with slit lamp biomicroscopy , keratometric measurements using an autorefractometer. The vertical width and horizontal length of the pterygium was measured manually with the millimetric scale of the slit lamp biomicroscope. Results: The study consisted of 45 patients with a mean age of 54.58 years. Mean Horizontal pterygium length, vertical width and percentage extension of pterygium was 2.71 mm, 4.56 mm, 50.22% respectively. Mean anterior corneal astigmatism was 2.11±1.69. Analysing the correlation separately, a statistically significant correlation was present between horizontal length and percentage extension and the anterior corneal astigmatism. Conclusion: Anterior corneal astigmatism was higher in pterygium group as compared to the contralateral eye without pterygium.
Impact of Commercial Herbicide, Bispyribac-Sodium, on Histological Feature and Functions of Catfish, Clarias gariepinus Liver

Hecommercial herbicide, bispyribac-sodium, is widely utilized in agricultural to control weeds in rice fields. Although, it ' s efficacy in controlling unwanted plant growth is well established, there are concerns about its potential effects on non-target organisms, such as the fish. Clarias gariepinus is a commonly farmed species of catfish and its health is of economic importance to aquaculture operations. The aim of the present work is to investigate the effects of bispyribac-sodium on the liver functions and it ' s histopathology in C. gariepinus . The study was conducted over a period of 14 and 28 days, with fish being exposed to varying concentrations of bispyribac-sodium (High and low concentrations). At the end of exposure period, blood and liver samples were collected for analysis the liver functions and its histopathology. Results showed that, exposure to bispyribac-sodium caused significant changes in the liver functions as indicated by altered levels of liver enzymes, including aspartate aminotransferase (ASAT), alanine aminotransferase (ALAT), alkaline phosphatase (ALP), albumin and total proteins. Histopathological examination of the liver tissue declared that exposure to bispyribac-sodium caused hepatic damage including centrilobular vacuolization, degeneration of the hepatocytes and infiltration of immune cells. Results suggested that, exposure to bispyribac-sodium can cause significant harm to the liver of C. gariepinus and raises concerns about its potential effects on the health of other aquatic organisms. Therefore, future studies must be conducted to fully understand the mechanisms underlying these effects and to assess the potential risks posed by bispyribac-sodium to the aquatic environment. Such study highlights the importance of considering the potential effects of agriculture’s chemicals on non-target organisms and knowledge for a more holistic approach to weed control in rice fields.
The Influence of Household Endowment on Settlement Choices in Cameroon

Household endowment has become a strong determinant of settlement choices. In spite of this trend, a quantitative assessment of the association between household endowment and settlement choices for policy implication is negligible in Cameroon. This paper seeks to bridge this gap by providing evidence on the extent to which household endowment influences settlement choices in Cameroon, using data from Cameroon’s 2011 Demographic and Health Survey, supplemented with a multiple indicators cluster survey. The survey used a national sample of 14,214 households, with sub-samples of 15,426 women and 7,191 men. Three questionnaires were used to collect information for the survey: a household questionnaire, an individual women’s questionnaire, and an individual men’s questionnaire. Choice of settlement was the dependent variable; with urban settlement being the base category. The independent variables included income level measured as wealth index, educational attainment, occupation and other demographic factors. Data was analysed quantitatively using Stata 14 and the binary probit estimation technique. The results indicated that educational attainment, income, gender, age of head of household and household size had a positive influence on the likelihood of urban settlement choices; while marital status and occupations had a negative effect on the likelihood of urban settlement choices. Based on these results, it is recommended that the government should enhance the potentials of rural areas to make them more attractive for settlement, a situation which will reduce urban population pressure and attract rural development. Besides, the government should construct social infrastructures and amenities in the rural areas to hearten household choice of rural settlement.
Effect of diet, breed and age at slaughter on the fatty acid composition of total lipid in beef longissimus muscle

Warren, H. E. , Enser, M. , Richardson, R. I. , Nute, G. , Wood, J. D. , Dhanoa, M. S. , Scollan, N. D. (2003). Effect of diet, breed and age at slaughter on the fatty acid composition of total lipid in beef longissimus muscle. Proceedings 7th British Grassland Society (BGS) Research Conference, Aberystwyth, 1-3 September 2003, BGS Organising Committee 25-26.
Agricultural Insurance in India: Problems and Prospects

The challenges of providing insurance to Indian agricultural sector in a manner that is both meaningful and sustaining. Critical assessment of the existing initiative and present possible options for improvement are presented. [NABARD Occasional Paper No. 44]. URL:[http://www.nabard. org/fileupload/DataBank/OccasionalPapers/OC%2044.pdf].
Pharmaceutical indication pictograms for low literacy viewers: Health literacy and comprehension

Background Poor comprehension of pharmaceutical pictograms used on medicine labels or leaflets can compromise understanding of medicine-taking information, potentially causing negative health outcomes. Aim The aim was to assess association of health literacy (HL) with comprehension of pictograms displaying indication and side effect information in a lower literacy, limited English proficiency (LEP) population. Setting Community centre, Makhanda, South Africa. Methods This was a quantitative cross-sectional study using simple random probability sampling. Ninety isiXhosa-speaking adults with a maximum of 12 years schooling, attending primary healthcare clinics were interviewed using structured interviews. Health literacy was assessed using the Health Literacy Test for Limited Literacy populations. Comprehension of 10 locally developed pictograms was evaluated. Results The mean pictogram comprehension score was 7.9/10, with 8/10 pictograms complying with the International Organization for Standardization criterion of 66.7% correct comprehension. Only 15.6% of participants had adequate HL. A significant association of HL with pictogram comprehension was established (p = 0.002). Pictogram misinterpretation was higher in those with lower HL; adequate HL was associated with superior comprehension. Pictogram comprehension was negatively associated with age (p < 0.006), and positively associated with education (p < 0.001) and English proficiency (p < 0.001). Conclusion Higher HL was associated with better pictogram comprehension. Low HL, LEP and low education levels are regarded as potential indicators for possible pictogram misinterpretation. Contribution This study observed the potential for misinterpretation of medication pictograms. Health professionals should be aware that low HL, limited schooling and limited English proficiency could signal difficulty in fully comprehending pictogram content.
College belonging among university students during COVID-19: An online interpretative phenomenological (OIPA) perspective

The purpose of this study was to identify the factors that either facilitated or complicated students' sense of school belonging and to determine the levels within the Ecological Systems Theory (EST) framework to which participants attributed these influential factors, using the Online Interpretative Phenomenological Analysis (OIPA) method. The OIPA approach is a qualitative research method and was used by the researcher for data collection and analysis in this study. Data were collected online using the OIPA form. The study cohort consisted of 82 university students (65% female, 35% male) from three different state universities in different cities in Türkiye. The results of the analysis revealed 20 facilitating factors, including elements such as friendships (33%), participation in activities and events (22%), and interactions with professors (20%). The study also identified 21 barriers, including economic challenges (39%), anxiety (32%), and experiences of exclusion and being ignored (29%). Participants attributed these facilitators and barriers to different levels of Ecological Systems Theory (EST). Specifically, they associated 63% of facilitating factors and 55% of complicating factors with the individual/intrapsychic level, 20% of facilitating factors and 51% of complicating factors with the microsystem level, 8% of facilitating factors and 26% of complicating factors with the exosystem level, and 15% of facilitating factors and 55% of complicating factors with the macrosystem level. Overall, participants linked 39% of facilitating factors and 52% of complicating factors to all levels combined.