Miracle-dz/UniFAR-FTUs huggingface dataset:
Effect of diverse fermentation treatments on nutritional composition, bioactive components, and anti-nutritional factors of finger millet (Eleusine coracana L.)

The finger millet ( Eleusine coracana L.) flour was subjected to lactic acid fermentation using two strains of Lactobacillus, that is, with Lactobacillus brevis (BF) and Lactobacillus plantarum (PF) , with yeast ( Saccharomyces cerevisiae L.) (YF) , and with yeast + ammonium sulfate used as fermentation activator (YAF) and combined treatment of yeast and L. brevis (CF) at an interval of 12, 24, and 36 h. The samples after drying were evaluated for their nutritional, anti-nutritional, minerals, and bioactive components. The total phenolic contents enhanced significantly ( P ≤ 0.05) during all fermentation treatments but the highest values were observed after PF treatment. Similarly, there was a significant ( P ≤ 0.05) enhancement in the antioxidant activity during all fermentation treatments, and the highest activity was observed during YAF treatment. Fermentation significantly ( P ≤ 0.05) enhanced the crude proteins content but decreased the crude fiber and fat contents. A significant ( P ≤ 0.05) increase in mineral content such as Cu, Fe, Mn, and Zn was observed after all fermentation treatments. Anti-nutrients such as phytic acid and tannins were reduced significantly ( P ≤ 0.05) and the greatest reductions were observed during treatment with L. brevis (BF). Similarly, the tannin contents get reduced significantly ( P ≤ 0.05) during all fermentation treatments. The present study, therefore, shows that fermentation could be the most effective method for improving the nutritional and bioactive components, as well as the antioxidant capacity of finger millet flour with a significant reduction in anti-nutritional components.
FAKTOR DAYA TARIK DAN KINERJA PELAYANAN MENURUT PERSEPSI MAHASISWA : STUDI FE UNNES

The objective of the research was to find the factors of the Economic Faculty s magnetism for Students Candidates to continue studying at the Economics Faculty, Semarang State University. Then, this study assessed the performances of those factors after they became Economics students. The sample of the study were Economics Faculty students from three departments; Accounting, Management, and Development Economics which consisted of 64 students on different semesters as th respondents. The data were analyzed by factor analysis to find the factors which became the Economics Faculty's magnetism. Then, the data were analyzed by Wilcoxon Rank Test to test the performances of those factors with the level of certainty was 95%. The result of the study showed that there were 4 main factors which became Economics Faculty' magnetism, they are; 1) Superiority, 2) Promotion, 3) Location and 4) Performance. Furthermore, the respondents stated that the performance of superiority factor was not satisfying while the performances of promotion, location and per formance factors were satis fying.
Phenethyl Isothiocyanate Suppresses the Proinflammatory Cytokines in Human Glioblastoma Cells through the PI3K/Akt/NF-κB Signaling Pathway In Vitro

Phenethyl isothiocyanate (PEITC), extracted from cruciferous vegetables, showed anticancer activity in many human cancer cells. Our previous studies disclosed the anticancer activity of PEITC in human glioblastoma multiforme (GBM) 8401 cells, including suppressing the cell proliferation, inducing apoptotic cell death, and suppressing cell migration and invasion. Furthermore, PEITC also inhibited the growth of xenograft tumors of human glioblastoma cells. We are the first to investigate PEITC effects on the receptor tyrosine kinase (RTK) signaling pathway and the effects of proinflammatory cytokines on glioblastoma. The cell viability was analyzed by flow cytometric assay. The protein levels and mRNA expressions of cytokines, including tumor necrosis factor-α (TNF-α), interleukin-1β (IL-1β), and interleukin-6 (IL-6), were determined by enzyme-linked immunosorbent assay (ELISA) reader and real-time polymerase chain reaction (PCR) analysis, respectively. Furthermore, nuclear factor-kappa B- (NF-κB-) associated proteins were evaluated by western blotting. NF-κB expression and nuclear translocation were confirmed by confocal laser microscopy. NF-κB binding to the DNA was examined by electrophoretic mobility shift assay (EMSA). Our results indicated that PEITC decreased the cell viability and inhibited the protein levels and expressions of IL-1β, IL-6, and TNF-α genes at the transcriptional level in GBM 8401 cells. PEITC inhibited the binding of NF-κB on promoter site of DNA in GBM 8401 cells. PEITC also altered the protein expressions of protein kinase B (Akt), extracellular signal-regulated kinase (ERK), and NF-κB signaling pathways. The inflammatory responses in human glioblastoma cells may be suppressed by PEITC through the phosphoinositide 3-kinase (PI3K)/Akt/NF-κB signaling pathway. Thus, PEITC may have the potential to be an anti-inflammatory agent for human glioblastoma in the future.
Contextualising simulation : the use of patient-focused hybrid simulation for clinical skills education

S = 85 Scanned for relevancy (2 reviewers) FULLTEXTS RETRIEVED= 13 Reviewed for relevancy (2 reviewers) STUDIES = 7 Included in systematic review Supplementary search = 1 (references, World Wide Web) EMBASE (from 1946), MEDLINE (from 1946), PSYCINFO (from 1967) till August 2011 Simulat$ AND (“Patient Focused” or “Hybrid”) (including related MESH terms) PFHS in Clinical Skills Education Jimmy Kyaw Tun 35 Exclusion Criteria: Non full-text and articles. Secondary studies, commentaries or opinion papers Subjective evaluation of training effectiveness, i.e. Kirkpatrick 1 Studies that only subjectively evaluate PFHS as an assessment tool, e.g. student and examiner acceptability. Poor or unclear study design Due to the heterogeneous nature of the study methods and outcomes, a meta-analysis was not performed. Instead, a qualitative synthesis of the finding was performed. Articles were reviewed for study aims, design, training and /or assessment methods, competency domain, outcomes and limitations.
Duration of Postoperative Analgesia with Intravenous Nalbuphine versus Intravenous Butorphanol in Patients Undergoing Short Surgical Procedures under TIVA

Aims and Objectives: To compare the duration of post operative analgesia of nalbuphine 0.3 mg/kg IV and butorphanol 0.04 mg/kg IV in patients posted for short surgical procedures under TIVA. Also to observe the sedation score as well as the side effects like nausea, emesis, pruritis, hypotension, respiratory depression. Materials and Methods: By closed envelope technique, sixty female patients of ASA Class I and II aged 20-60 years, who were posted for short gynaecological surgeries under TIVA were randomly allocated into two groups: Group N (nalbuphine) and Group B (butorphanol). Just prior to surgery, Group N patients got IV Nalbuphine 0.3 mg/kg, while Group B patients received IV Butorphanol 0.04 mg/kg. Patients were asked to rate their pain intensity on a VAS scale in the course of the postoperative period, and the duration of postoperative analgesia was compared between the two groups. The Modified Ramsay sedation scale was exercised to assess sedation at the time of pain complaint, and patients were additionally monitored for 24 hours post the surgery for any adverse or side effects. Results: In group N, 63.33% of patients had duration of pain relief ranging 31-50 minutes, with mean duration of analgesia being 46.333 ± 2.061. In group B, 60% of patients had duration of pain relief ranging from 11-30 minutes, with mean duration being 19.167± 1.68 minutes. In group N, 63.33% of patients had score for sedation as 3 and rest (36.67%) had a score for sedation as 2. In group B, 80% of patients had a score for sedation as 2 and rest (20%) had a score for sedation as 1. Conclusion: When compared to IV Butorphanol, intravenous Nalbuphine delivers a more effective post-operative analgesia with better sedation. IV Nalbuphine is recommended for post operative analgesia in patients undergoing short surgical procedures. Both the drugs did not cause any side effects.
Comparative Evaluation of Crestal Bone Loss around Compression Screw Implants Placed in Healed Sites and Freshly Extracted Sockets

Aim: The aim of the study was to evaluate crestal bone loss around immediate loading compression screw implants. Study Design: A Randomized controlled clinical trial. Method: In this randomized study, 15 subjects with 30 edentulous sites in the maxillary and mandibular anterior regions (incisors and canines) willing for replacement were taken into consideration. A total of 14 implants were placed in healed sites and 16 implants were placed in freshly extracted sockets and immediately loaded in both groups. Provisional restoration was delivered on the same day of implant placement. Crestal bone loss was evaluated at baseline (immediately after implant placement), 1 month, and 4 months. The final prosthetic restoration was delivered after 4 months following implant placement. Results: No statistically significant difference for crestal bone loss was observed between delayed and immediate implant placement at 4 months interval. Conclusion: Within the limitations of this study, immediate placement of one-piece implant produced crestal bone loss comparable to delayed placement. The unique design of a one-piece implants eliminates the fixture abutment interface (microgap) and resembles the natural tooth with a seamless transition of the radicular unit to the coronal unit. Therefore, in the maxillary and mandibular anterior regions, one-piece implants with immediate loading can be considered as a viable solution for the replacement of missing teeth with better esthetics.
The Influence of Word-of-web on Customers’ Purchasing Process: The Case of Xiaohongshu

ABSTRACT Word-of-web (WOW) today has become crucial to exchange marketing information between customers via online platforms. However, there is a lack of research on the marketing potency of WOW on customer purchasing process. This study employed expectancy-confirmation theory (ECT) and trust factors to understand consumers’ purchasing process using WOW on Xiaohongshu, a Chinese social media and e-commerce platform. Due to its popularity and representativeness among digital marketing platforms, it was chosen as a case study. The process is studied in three periods: pre-purchase, transaction, and post-purchase. In pre-purchase period, users are suspicious of WOW, though it can trigger high expectations with appealing display. During transaction period, people generally have a positive expectation confirmation of using Xiaohongshu to purchase F&B services and it was further discovered that moment-of-truth can contribute to overall satisfaction. Nonetheless, at post-purchase period, the intention of re-visiting restaurants is low while the continuity with Xiaohongshu is affirmative. The strong perceived usefulness leads to users’ loyalty to the app even with a negative catering experience. This paper contributes to revising and extending the application of the ECT model in explaining customers’ purchasing process based on WOW. It also helps marketers make adaptive management decisions regarding online marketing with WOW.
Comparison of Clinical Profiles, Angiographic Features and Outcomes of Young and Elderly Patients with ST-Segment Elevation Myocardial Infarction

Objective: It is to reveal the differences between clinical, angiographic, in-hospital and one-year follow-up results between young and elderly patients with acute ST-segment elevation myocardial infarction. Material and Methods: This study was designed retrospectively in two centers. 2891 patients were screened; 260 of which were young. 260 elderly patients were randomly selected among the patients and the differences between both groups were evaluated. Results: The median age of the young patients was 37 (34-39) years and the median age of the elderly patients was 65 (56-73) years, and male gender was dominant in both groups. Young patients were more likely to be admitted with Killip class 1, while older patients were more likely to be admitted with Killip class 2 (P=0.002). Single-vessel disease was more common in young patients (81.0% vs. 46.3%; P<0.001), while multi-vessel disease was more common in the elderly patients (19.0% vs. 53.7%; P<0.001). In one-year follow-up, all-cause hospitalization was lower in younger patients, but there was no significant difference in mortality between elderly and young patients. Conclusion: Young patients presenting with ST-segment elevation myocardial infarction were more frequent smokers, obese and dyslipidemic and although in-hospital outcomes were better than the elderly, one-year mortality was similar to those of the elderly.
Experimental Study on Improvement The Performance of Savonius Windmill with Ventilated Blade

This study aims to determine how much influence the use of fixed ventilation on the blade towards improvements in performance Savonius windmill. Ventilation is made in the form of a reflection on the letter C. The ventilation open into the concave side of the blade. There are one model of the conventional Savonius windmill and six models of the ventilated Savonius windmill that tested in the wind tunnels. Experimental variables are variations in the clearence width of the ventilation, variations in wind speed and variations in rotor rotation. Further more, rotor Savonius turn mini-dynamo (magneto) to get current and voltage. The ventilated Savonius windmill have the average useful power and the power coefficient higher than the conventional Savonius windmill. Especially for the clearance width of ventilation is 0.05 to 0.10 of the diameter of the blade.
Antecedents of Domestic Tourists’ Loyalty: The Role of Place Attachment and Satisfaction

Place attachment is conceptualized as a multidimensional construct reflecting the bond between individuals and places. Tourists may also develop an attachment to a destination, and attachment could be an essential measure of tourist satisfaction and destination loyalty. Therefore, this study empirically evaluates a model linking place attachment, satisfaction, and destination loyalty. The study also analyses the mediating effect of satisfaction on the relationship between place attachment and destination loyalty in island tourism destination context. Data were collected from 311 domestic tourists visiting Bozcaada Island, Turkey. An analysis was carried out using a Partial Least Squares (PLS) technique through structural equation modelling to test the theoretical model. After the analysis, significant and positive relationships were determined between place attachment, satisfaction, and destination loyalty variables. With this research, place attachment and satisfaction are defined as the antecedents that have an important place in the formation of destination loyalty. The relations of these antecedents with each other and destination loyalty and their direct and indirect effects on the construction of loyalty are revealed. In line with these effects, a series of suggestions for literature and practice are presented.
Effects of Peroxiredoxin 6 and Its Mutants on the Isoproterenol Induced Myocardial Injury in H9C2 Cells and Rats

Background Peroxiredoxin 6 (PRDX6) is an important antioxidant enzyme, with a potential application value in the treatment of diseases caused by oxidative damage. Methods PRDX6 and a mutant (mPRDX6) were heterologously expressed by using an E.coli expression system and purified by Ni-affinity chromatography. Isoproterenol (ISO) was used to induce a myocardial cell injury model and an animal myocardial injury model. After the treatment with PRDX6 and mPRDX6, the proliferation activity of H9C2 cells was detected by Cell Counting Kit-8 (CCK8) method; the apoptosis was evaluated by flow cytometry, and the histological changes of myocardial cells were observed by hematoxylin and eosin (H&E) staining, the levels of catalase (CAT), glutathione peroxidase (GPX), malondialdehyde (MDA), and superoxide dismutase (SOD) in ISO-treated H9C2 cells as well as in the heart tissue and serum of rats treated with ISO were detected, and the expression levels of Bax, Bcl-2 and peroxisome proliferators-activated receptors-γ (PPAR-γ) proteins were detected by Western blot. Results PRDX6 and mPRDX6 were successfully expressed and purified. The results of efficacy study showed that the mutant mPRDX6, in which the phospholipaseA2 (PLA2) activity of PRDX6 was deleted by site directed mutation, had a better protective effect against the myocardial injury than PRDX6. CCK8 results showed that compared with that in ISO group, the proliferation activity of H9C2 cells was significantly enhanced (P < 0.01), the apoptosis rate was significantly decreased (P < 0.01), and the fluorescence intensity of reactive oxygen species (ROS) was significantly decreased (P < 0.01) in mPRDX6 group. The results of H&E staining showed that the myocardial injury was alleviated to a certain extent in mPRDX6 group. Compared with those in ISO group, the activities of CAT, GPX, and SOD in H9C2 cells and the heart tissue and serum of rats were significantly increased (P < 0.05), while the contents of MDA were significantly decreased (P < 0.05). Western blot analysis showed that the expression level of Bcl-2 in H9C2 cells was significantly decreased (P < 0.01), and that of Bax and PPAR-γ was significantly increased (P < 0.05). Conclusion mPRDX6 has a protective effect against the myocardial injury induced by ISO, and the mechanism may be related to its antioxidation. This study may provide a theoretical basis for the research and development of drugs used for the treatment of myocardial injury.
Teachers’ Financial Literacy

The aim of the research is to explore the financial knowledge, attitudes, confidence, behaviour and motivations of teachers (N=752) teaching different subjects. The survey is particularly important because their knowledge, attitudes, and behaviours affect the financial awareness of the students they teach. The results indicate a higher level of financial literacy than assumed, revealing that teachers have a higher level of financial literacy than students in higher education. 86% of those surveyed have savings in addition to bank deposits, such as government bonds and other, more complex forms of savings, indicating a high level of financial awareness and inclusion. Teachers highly value their own financial literacy, and similar to those studying in higher education, are risk averse. Their vast majority consider the development of financial literacy in schools important. Financial literacy trainings have a measurably positive effect on the level of knowledge of the participants. Based on the results of the research, it is worthwhile to shape the curricula and the requirements based on the financial awareness and motivation of the teachers.
Seasonal effect on the diversity of soil fungi and screening for arsenic tolerance and their remediation

The seasonal variations were closely linked to climatic factors such as air temperature, rainfall, humidity, and other factors, all of which had a significant impact on soil characteristics, organic matter, and microbial population. The nutritional and physicochemical characteristics of their environment have an impact on soil microbe survival and dissemination. Heavy metal deposition in soil and plants, both edible and non-edible components, is linked to the consumption of heavy metal contaminated foods and the substantial health risks they provide. Seasonal diversity of soil fungi, as well as the screening of arsenic-resistant fungi and their ability to play a substantial role in bioremediation, was investigated in this work. The highest number of fungal species (17) was likewise found in the winter season, while the lowest number of species (11) was found in the summer. There were seven Aspergillus species, four Penicillium species, two Alternaria species, and single species of other fungi found. During the monsoon and winter seasons, the population of Aspergillus niger was at its peak. The genus Penicillium, on the other hand, reaches its peak number during the summer. Five fungi, Aspergillus nidulans, A. niger, Aspergillus sp. isolate HKK4, Aspergillus sp. , and Penicillium sp. , were found as arsenic tolerant. Aspergillus sp. isolate HKK4, which was isolated as arsenic tolerant and could tolerate more than 500 ppm of arsenic, outperformed all other fungus in terms of P-solubilization and arsenic removal.
Impact of the Great Flood of 2016 on the Asphaltic Concrete Road Infrastructure in Louisiana

Extreme weather events, including inundation, are the major causes of weather-related disruption to the transportation sector. Considerable research has been conducted in recent years to evaluate the impacts of inundation on pavement functional and structural conditions. Yet, limited studies quantified how inundation may affect the long-term pavement performance and pavement life-cycle costs. As such, the main objective of this study was to quantify the impact of the 2016 inundation event in Louisiana, U.S., on the long-term pavement performance (in relation to reduction in the pavement service life [PSL]) and on pavement life-cycle costs. To achieve this objective, a total of 10 inundated pavement sections were evaluated. Pavement conditions, fatigue, and rutting indices for these sections were analyzed over a monitoring period of up to 15 years (11 years before and 4 years after inundation). Results indicated that the 2016 inundation event reduced the PSL of the inundated sections to an extent that depended on their pre-flooding pavement condition, traffic level, and asphalt concrete thickness. This reduction was attributed to the accelerated fatigue, rutting damage, or both, that resulted from prolonged water submergence and heavy traffic loading during debris hauling that took place after the inundation event. A logistic regression model with adequate accuracy was developed to predict whether an inundated pavement would experience reduction in its PSL based on the project conditions. The study findings were incorporated into a simple tool to assist transportation agencies make effective decisions for the maintenance and rehabilitation of inundated pavements.
Spatial Variations in Magmatic Volatile Influx and Fluid Boiling in the Submarine Hydrothermal Systems of Niuatahi Caldera, Tonga Rear‐Arc

Submarine caldera volcanoes may host several hydrothermal systems along the caldera wall and related to volcanic cones. Fluid boiling and magmatic volatile influx are common processes in shallow (<2,000 mbsl) subduction zone‐related environments causing variations in the mineralogical and chemical composition of seafloor hydrothermal mineralizations that remain poorly constrained. The submarine caldera of Niuatahi volcano, Tonga rear‐arc, hosts four active vent sites discharging high temperature fluids (<334°C) with variable salinities (369–583 mM Cl) that are indicative of fluid boiling, recorded by distinct Te/As and Te/Au in pyrite, sphalerite, and chalcopyrite. High sulfidation mineral assemblages (e.g., enargite), stable S isotope data and similar trace element signatures in sulfides and native S condensates suggest a minor and/or infrequent contribution of magmatic SO2 to the hydrothermal systems located proximal to the caldera center causing a volatile element (e.g., Se, Bi, Te) enrichment. The hydrothermal system at the northern caldera wall is decoupled from the magmatic SO2 source, as revealed by radiogenic Pb isotopes. Instead, S isotope and trace element constraints propose a host rock‐dominated hydrothermal system, lacking a magmatic volatile influx. The observed hydrothermal fractionation processes (fluid boiling) and the distinct metal (loid) sources (magmatic volatiles vs. host rock) represent a continuum from magmatic volatile‐ to host rock‐dominated hydrothermal systems within the Niuatahi caldera. This leads to seafloor mineralizations with spatially selective trace element enrichments, like Te, Se, and Bi (±Au, Ag) in the caldera center compared to Au, Ag, Zn, Cd, and Pb at the northern caldera wall.