Miracle-dz/UniFAR-FTUs huggingface dataset:
Is cardiac failure a consequence of decreased energy reserve

Background. The hypothesis that the failing heart is an energy-starved heart has been difficult to test. By use of new techniques of 31 P nuclear magnetic resonance spectroscopy coupled with biochemical analyses, it is now possible to test some aspects of this hypothesis. Here, we summarize and critique the evidence relating to the role of the primary energy reserve system in heart, namely, the creatine kinase system (phosphocreatine [PCr]+ADP⇄creatine+ATP) in hypertrophied and failing myocardinm. Methods and Results. Whole-organ enzymology of the creatine kinase system was defined by use of biochemical an biophysical tools: total creatine kinase activity (V max ), isoenzyme distribution, concentrations of substrates and products, pH, and unidirectional reaction velocity, i.e., PCr→[γ-P] ATP
Evaluation of antioxidant activities in ethanolic extract of Capparis Zeylanica Linn. Root.

The in vitro antioxidant activity of the Capparis Zeylanica extract showed that has a scavenging ability of hydroxyl peroxide radicals (421.74 ± 25.61 mg/ml) and DPPH radical scavenging activity (around 95%). In vivo study in rats with Capparis Zeylanica extract showed significant antioxidant activity in the DPPH test as compared to the control. Capparis Zeylanica extract at doses of 100 and 200 mg/ kg significantly increased rats TAP as compared to control where as the decreased in TBARS was significant in 200 and 400 mg/kg compared to the control. Administration of Capparis Zeylanica extracts at a dose of 400 mg/kg per day did not significantly alter serum TAP but little alteration was observed in TBARS test. Antioxidant activities of the extract at doses of 100 and 200 mg/kg were in all experiments comparable to that of α-tocopherol (10 mg/kg). A good result for DPPH and TBARS was found at a dose of 400 mg/kg compared to the α-Tochopherol. Dose dependent effect was found in DPPH scavenging activity. The constituents like total phenolic compounds (43.625±1.45 mg/g of dry extract), total tannins (24.75±1.23 mg/g of dry extract), total flavonols (1.653 ± 1.41mg rutin equivalents/g dry extract), total flavonoids (0.876±0.26 mg/g Rutin/g of dry extract), Saponins (1.22±1.35 mg/g of dry extract) and fatty acids (0.0867 ± 0.01 mg/g of dry extract) indicate that the Capparis Zeylanica root extract may contribute to the antioxidant activity. www.relaquim. com
ANALISIS PENGARUH BRAND IMAGE, HARGA, KUALITAS PRODUK, DAN DAYA TARIK PROMOSI TERHADAP MINAT BELI ULANG KONSUMEN BATIK PEKALONGAN (STUDI PADA PASAR GROSIR SETONO BATIK PEKALONGAN)

Penelitian ini bertujuan untuk mengetahui pengaruh brand image, harga, kualitas produk dan daya tarik promosi berpengaruh pada minat beli ulang konsumen batik Pekalongan. Teknik pengambilan sampel yang digunakan dalam penelitian ini adalah teknik purposive sampling yaitu teknik ini dipilih karena peneliti menggunakan pertimbangan sendiri dalam memilih anggota populasi yang dianggap dapat memberikan informasi sedangkan jumlah sampel sebanyak 97 responden. Teknik pengumpulan data menggunakan kuesioner. Hasil penelitian ini dikumpulkan melalui kuisoner yang diproses dan dianalisis dengan menggunakan analisis regresi linier berganda metode yang digunakan dalam penentuan sempel dalam penelitian ini adalah purposive sampling. Uji kualitas data yang digunakan dalam penelitian ini adalah uji validitas Person Correlation, uji reliabilitas menggunakan Cronbach Alpha dan uji goodness of fit (uji f). Untuk uji asumsi klasiknya menggunakan uji normalitas, uji multikolonieritas dan uji heteroskedasitas. Untuk uji hipotesis dalam penelitian ini, peneliti menggunakan regresi linier berganda, uji t dan koefisien determinasi 〖(uji R〗^2). Hasil data penelitian ini menunjukan bahwa brand image berpengaruh positif dan signifikan terhadap minat beli ulang konsumen batik Pekalongan, harga tidak berpengaruh dan tidak signifikan terhadap minat beli ulang konsumen batik Pekalongan, kualitas produk positif berpengaruh dan signifikan terhadap minat beli ulang konsumen batik Pekalongan, dan daya tarik promosi tidak berpengaruh dan tidak signifikan terhadap minat beli ulang konsumen pada batik Pekalongan
The Impact of TOEFL on Instructors' Course Content and Teaching Methods.

Even though there are books that guide students in preparing for TOEFL exams, the literature on TOEFL test preparation courses at the university level is sparse (Huang, 2018). The current study aimed to fill the research gap by investigating the impact of TOEFL ITP assessment on teachers’ TOEFL course content and teaching methods. Five different TOEFL classes and four TOEFL instructors participated in the study. Following a qualitative research design (Glesne, 2015), fourteen classroom observations, fourteen student interviews, and four teacher interviews were collected. A combination of the Communicative Orientation of Language Teaching (COLT) observation scheme (Spada & Frohlich, 1995) and Miles & Huberman's (1994) inductive approach were used to analyze classroom observations. The results from the observations were triangulated with student and teacher interviews. Findings indicated that teachers relied on the TOEFL textbooks to teach and practice test-taking strategies. They followed a “teach-model-practice-explain” structure during their instruction and spent the majority of class time conducting teacher-centered activity and student-alone activity. Additionally, teachers’ beliefs shaped their teaching methods, and their different beliefs led to students’ varied attitudes toward the TOEFL class. Pedagogical implications of implementing TOEFL classes at English language programs were discussed.
Soil biochemical properties and growth of Ber and Aonla as influenced by bio-inoculants

Monitoring soil biological productivity as influenced by inoculation with beneficial microorganisms may provide useful information about the potential of soil for providing available forms of various elements and is mainly responsible for improving the soil fertility status and higher plant productivity. Soil microbiological properties often change when different cropping, tillage or management system other than the conventional cultivation practices are imposed. The effect of inoculation of nitrogen fixing bacteria and arubuscular mycorrhizal (AM)-fungi alone or in combination on activities of various enzymes in the rhizosphere of ber and aonla were assessed. Activities of soil dehydrogenase and phosphatases were significantly improved upon inoculation with Azospirillum/Azotobacter and G. fasctculatum. Soil nitrogen fixing potential, as measured by nitrogenase activity, was maximum with dual inoculation of both these organisms. Inoculation enhanced the root infection and density of AMF spores. The result of the study demonstrated the potential value of inoculation with beneficial microorgansims in enhancing the soil biological processes. Additionally the inoculation had improved the soil fertility status resulting in a significant increase in the leaf area and biomass production of ber and aonla.
Heritability estimates and genetic and phenotypic correlations of lamb production parameters with hogget liveweight and fleece traits in Western Australian Merino sheep

Heritability estimates (h 2 ) for weight of lamb weaned and number of lambs weaned totalled over 3 reproduction opportunities were estimated in a multi-bloodline Western Australian medium wool resource flock. These traits were defined to give an indication of lifetime lamb production (the ewes were retained in the breeding flock for a maximum of 4 lambing opportunities). Both reproduction traits were highly variable, as suggested by coefficients of variation of approximately 50%. The between-bloodline variance ratio was significant (P < 0.05), but failed to exceed 5% of the total across-bloodline phenotypic variation. Within-bloodline h 2 (± s.e.) was estimated at 0.154 ± 0.040 for total weight of lamb weaned, and at 0.141 ± 0.040 for total number of lambs weaned. Within-bloodline genetic correlations of both traits with hogget liveweight were positive and significant (P < 0.05; 0.58 ± 0.11 and 0.26 ± 0.13, respectively). Within-bloodline genetic correlations of the reproduction traits with wool production were generally positive, being 0.26 ± 0.11 for the correlation between total weight of lamb weaned and clean fleece weight, and 0.29 ± 0.15 for the correlation between total number of lambs weaned and clean fleece weight. Clean yield was genetically unrelated to both measures of reproductivity. The genetic correlation of total weight of lamb weaned per breeding ewe with fibre diameter was positive in sign, but smaller than twice its standard error (0.17 ± 0.10). The corresponding estimate for total number of lambs weaned was 0.16 ± 0.12. It was concluded that the reproduction traits investigated would respond to selection in Western Australian Merinos if it should form part of a breeding strategy. Genetic correlations with hogget liveweight and wool traits were generally favourable. Additional keywords: lamb production, liveweight, fleece weight, fibre diameter. Ge a l ti A e et
Coniferous Ovulate Cones from the Lower Cretaceous of Santa Cruz Province, Argentina

Two types of coniferous ovulate cones borne on leafy twigs are described from the Lower Cretaceous Kachaike Formation in Santa Cruz Province, Argentina. The fossils are impressions and compressions with well‐preserved cuticles. Morphology, anatomy, and ultrastructure were studied using LM, SEM, and TEM. Ovulate cones were assigned to Athrotaxis ungeri (Halle) Florin of the taxodiaceous Cupressaceae and Kachaikestrobus acuminatus gen. et sp. nov. of the Cheirolepidiaceae. This latter taxon is characterized by terminal elongate cones borne on twigs with Brachyphyllum leaves, cone scales densely and helically disposed, broad bracts with an accentuated acuminate apex fused at their bases to eight‐lobed ovuliferous dwarf shoots shorter than the bracts, and an epimatium covering at least one ovule that has preserved only the outer integument and the megaspore membrane. The ultrastructure of the bract and ovuliferous dwarf shoot cuticle is composed of three layers. Comparisons of K. acuminatus with other cheirolepidiaceous ovulate cones showed closest resemblance to Hirmeriella muensteri (Schenk) Jung. These Patagonian cone scales appear to have some of the most ancestral characters in the family. By the early Albian, A. ungeri and K. acuminatus were part of a plant assemblage dominated by ferns and a few subordinate angiosperms. The finding of A. ungeri in the Kachaike Formation extends its distribution during the Lower Cretaceous in Patagonia. These fossils also show that at that time, the taxodiaceaous Cupressaceae and the Cheirolepidiaceae still were well represented in southern South America.
Zinc partitioning in maize grain after soil fertilization with zinc sulfate.

Maize (Zea mays L.) is high nutrient demanding crop but sensitive to zinc (Zn) deficiency in soil. Application of Zn fertilizers could be a viable option to fulfill the crop demand for Zn and also to increase its contents in grains. A field experiment was conducted to evaluate the effect of supra-optimal rates of Zn application on maize cultivars. A selected maize hybrid (FHY421) and a synthetic variety (Golden) were grown at four different rates of Zn application along with recommended doses of nitrogen, phosphorus and potassium. Cobs were harvested; grains were separated and analyzed for their Zn content. Response of genotype varied to different Zn application rates. Maximum grain yield and Zn uptake in maize hybrid (FHY-421) was noted at 18 kg Zn ha -1 . However synthetic variety (Golden) exhibited maximum grain yield and Zn uptake when Zn was applied @ 9 kg ha -1 . Maize response curve showed that for optimum grain yield, Zn concentration in hybrid was found 28.2
Assessment of welfare in pigs

Abstract According to the definition given by Appleby (1996), animal welfare represents the state of well-being brought about by meeting the physical, environmental, nutritional, behavioural and social needs of the animal or groups of animals under the care, supervision or influence of people. Suitable husbandry techniques and disease control (in which man is directly involved) may satisfy an animal’s physical, environmental and nutritive needs. However, it cannot be stated that people’s supervision or influence always guarantee the satisfaction of behavioural and social needs. Thus, special attention must be paid to these factors in intensive husbandry. This paper calls attention to the main factors characterizing pig welfare on the basis of productive, physiological, pathological and behavioural indicators; to the behavioural needs, which are characterised by several peculiar traits (it is noteworthy that, since the beginning, all categories of reared pigs have been involved in welfare legislation); to all categories of pigs that often show the effects of negative stimuli on their behaviour (limitations, variations); to the main critical points on the farm likely to cause welfare impairment or stress including buildings, inner facilities, space allowance, microclimate, lighting systems, environmental stressors, feeding management, mutilations, weaning, social factors, and stockmanship; and to environmental stressors including dust, odours (especially ammonia) and noises. This paper takes into account sources, effects and possible solutions for noises; the positive effect of fibrous feeding; environmental enrichment and other possible techniques for improving social status and for preventing/reducing stereotypic behaviour and abnormal reactions (e.g. tail biting). The scientific/objective evaluation of welfare for intensively reared pigs may be carried out by means of direct observation of the animals themselves (animal-based or encompassing performance or output criteria), as well as through examinations of a structural nature (design or resource-based, or derived from engineering or input criteria). Preference should be given to the former since they are can be better adapted to the different pig categories and management systems. Design criteria, on the other hand, are easier to evaluate and they should integrate animal criteria. Thus, the most correct protocols for on-farm evaluation of pig welfare should involve both animal-based criteria and design criteria. Examples of both criteria are reported herein. In extensive farming which includes (although somewhat improperly) outdoor and organic farming, achieving a good level of welfare is one of the declared objectives. However, there are several causes of welfare impairment that can be successfully overcome only if highly professional workers are employed: unfavourable climate, parasitic diseases, intake of plants containing poisons or anti-nutritional factors, high piglet mortality.
Trialing project-based learning in a new EAPESP course: A collaborative reflective practice ofthree college English teachers

Currently in many Chinese universities, the traditional College English course is facing the risk of being ‘marginalized’, replaced or even removed, and many hours previously allocated to the course are now being taken by EAP or ESP. At X University in northern China, a curriculum reform as such is taking place, as a result of which a new course has been created called ‘xue ke’ English. Despite the fact that ‘xue ke’ means subject literally, the course designer has made it clear that subject content is not the target, nor is the course the same as EAP or ESP. This curriculum initiative, while possibly having been justified with a rationale of some kind (e.g. to meet with changing social and/or academic needs of students and/or institutions), this is posing a great challenge for, as well as considerable pressure on, a number of College English teachers who have taught this single course for almost their entire teaching career. In such a context, three teachers formed a peer support group in Semester One this year, to work collaboratively co-tackling the challenge, and they chose Project-Based Learning (PBL) for the new course. This presentation will report on the implementation of this project, including the overall designing, operational procedure, and the teachers’ reflections. Based on discussion, pre-agreement was reached on the purpose and manner of collaboration as offering peer support for more effective teaching and learning and fulfilling and pleasant professional development. A WeChat group was set up as the chief platform for messaging, idea-sharing, and resource-exchanging. Physical meetings were supplementary, with sound agenda but flexible time, and venues. Mosoteach cloud class (lan mo yun ban ke) was established as a tool for virtual learning, employed both in and after class. Discussions were held at the beginning of the semester which determined only brief outlines for PBL implementation and allowed space for everyone to autonomously explore in their own way. Constant further discussions followed, which generated a great deal of opportunities for peer learning and lesson plan modifications. A reflective journal, in a greater or lesser detailed manner, was also kept by each teacher to record the journey of the collaboration. At the end of the semester, it was commonly recognized that, although challenges existed, the collaboration was overall a success and they were all willing to continue with it and endeavor to refine it to be a more professional and productive approach.
KRAS Codons 12 and 13 Mutation Analysis: A Comparative Study between Direct Sequencing and a New Sensitive Real-Time PCR Assay

KRAS somatic mutations are found in 30–40% of colorectal cancer (CRC). Seven mutations in codons 12 and 13 of KRAS (95% of the observed human mutations) preclude the efficacy of anti-EGFR therapy for the treatment of CRC. Assessment of KRAS mutational status has become a standard procedure in the management of patients with CRC. Technically, KRAS mutation testing can be performed with different methods, characterized by distinct sensitivities and specificities. The present study analyzed KRAS in 182 CRC histological samples by using direct sequencing and a new kit based on a Real-Time Sequence-Specific Primers-PCR technology. The kit allowed to recover as positive 17 samples that were negative or unclear by sequencing, with a recovery rate equal to 13.82%. This study proposes a fast, sensitive, and high-throughput system to identify such seven described mutations of KRAS gene in CRC samples.
Vascular Systemic Induced Resistance For Artemisia cana and Volatile Communication for Artemisia douglasiana

ABSTRACT Recent work has demonstrated that communication between plants in natural settings can increase resistance against herbivores. However, this phenomenon has been found convincingly for only two species, alder (Alnus glutinosa) and sagebrush (Artemisia tridentata), and recent reviews have questioned the commonness of this phenomenon. Results from experiments involving sagebrush suggest that vascular signaling among branches within an individual is limited and that sagebrush may use external volatile cues instead. Communication among individuals may be a byproduct of volatile communication among branches of a single individual. We tested this hypothesis by examining systemic induced resistance and communication between individuals for two naturally occurring species of Artemisia. Artemisia cana exhibited systemic induced resistance without volatile cues. Assay branches on plants with experimentally clipped treatment branches experienced less herbivory than assay branches on unclipped controls even when air contact was blocked. We found no evidence of airborne communication between A. cana individuals that affected herbivory. Branches of A. douglasiana appeared to exhibit systemic induced resistance to experimental clipping. In addition, assay branches on plants with experimentally clipped neighbors received 45% less chewing damage than assay branches with unclipped neighbors. Although stems may have been connected by rhizomes, communication between stems required air contact. In summary, for one of two Artemisia species considered, we found evidence for volatile communication between stems that affected their tissue losses to herbivores. These results suggest that volatile communication among stems or individuals may not be an unusual phenomenon, at least within the genus Artemisia.
REVISION OF THE TEETH OF THE GENUS CARCHARHINUS (ELASMOBRANCHII; CARCHARHINIDAE) FROM THE PLIOCENE OF TUSCANY, ITALY

The great similar tooth morphologies that characterized the sharks of the genus Carcharhinus have suggested that the Neogene Mediterranean Sea were inhabited by only one or two widespread carcharhinid taxa, Carcharhinus egertoni and C. priscus . The first Mediterranean Pliocene record of five new shark species included into Carcharhinus , C. aff. brachyurus , C. falciformis , C. leucas , C. perezi, and C. plumbeus , have been identified by the review of some shark teeth from Tuscany (Italy) and housed in the Italian Museums of the Universities of Firenze, Bologna, and Pisa. Moreover, the Mediterranean records of the two Recent C. longimanus and C. obscurus has been confirmed too. Paleobiogeographic and palaeoecologic analysis have been produced on the presence of some species absent or doubtful for the extant Mediterranean shark community.
Responses of Subterranean Clover Communities to Temperature. II. Effects of Temperature on Dark Respiration Rate

The rates of dark respiration of subterranean clover communities, grown at 12, 16, 20 and 24°C in naturally lit temperature-controlled glasshouses, were measured several times during growth. The dark respiration rate, measured at growth temperature, increased linearly with increase in plant dry matter for each temperature and it increased approximately linearly with increase in temperature at a given dry matter. A low crop growth rate shown by communities with dry matter greater than 300 g m-2 at a temperature of 24°C was largely accounted for by a high respiration rate. The temperature coefficient of dark respiration (Q10) was inversely related to growth temperature. Dark respiration rate at 28°C was lower for communities grown at 24°C than for communities grown at 12 or 16°C when the comparison was made at the same dry matter. Calculated dark respiration rate from shoot dry matter, growth temperature and current measured temperature was close to the measured rate, indicating the dark respiration rate of subterranean clover communities to be largely accounted for by these factors. Use of an integrated form of a growth equation and allowing for dark efflux shows, on a 12 hour day, the rate of dry matter accumulation at 24°C to be the same as that at 12°C.
The effect of age and sex on slaughter traits of pheasants (Phasianus colchicus L.).

Slaughter traits were evaluated in pheasants slaughtered at the age of 12, 16 and 20 weeks. No significant differences between week 16 and 20 were found in the trunk length with the neck, trunk length, breast bone length and circumference and width of the chest as measured on the carcass, as well as in the weight of eviscerated carcass with the neck, dressing percentage and muscle content of carcass. The results show a feasibility of completing the rearing of slaughter pheasants between week 16 and 20 of life. The traits affected neither by age nor by sex of birds were the dressing percentage, breast and leg muscles content of carcass (%) and the content (%) of skin with subcutaneous fat.