Miracle-dz/UniFAR-FTUs huggingface dataset:
Determinants of Environmental Disclosure in Indonesia

This study aims to identify the impacts of audit committees, audit committee meetings, and boards of commissioner meetings (BCM) on environmental performance and environmental disclosure (ED). The population of this study was 89 companies listed in LQ45 for the period 2011-2016. By using purposive sampling technique, this study identified 23 companies as samples. Path analysis based on the structural equation model was used. Environmental performance had a significant and positive effect on ED, audit committee meetings also determined ED and BCM, but have no effect on environmental performance. BCM did not have any significant effect on environmental performance. Audit committee had a significant positive effect on audit committee meetings. While size had a positive effect on the audit committee and BCM but did not affect the audit committee meeting. These results indicate that the discussion in audit committee meetings and BCM focused more on the ED rather than environmental performance.
A economia política do complexo Soja-Carne Brasil-China

The argument developed in the paper, based on the food regime approach, is that the formation of the “Brazil-China soy-meat complex”, from the early 2000s, represents a polycentric shift in global agri-food relations, driven by the interests of agribusiness corporations and food industries, as well as national states, in a South/East direction, which challenges the established power of the 1 O presente trabalho foi realizado com apoio da Coordenação de Aperfeiçoamento de Pessoal de Nível Superior – Brasil (Capes), Programa de Pós-Doutorado no Exterior, Processo n. 88881.171596/2018-01. Data de submissão: 31 de janeiro de 2018. Data de aceite: 28 de julho de 2018. 1. China Agricultural University, Beijing, China. E-mail: escher_fab@hotmail.com 2. Universidade Federal Rural do Rio de Janeiro (UFRRJ), Rio de Janeiro (RJ), Brasil. E-mail: jhn. wlknsn@gmail.com 657 Escher, F. , & Wilkinson, J. ♦ Revista de Economia e Sociologia Rural, 57(4), 656-678, 2019 657/ 678
Estado del proceso administrativo en las unidades de producción agropecuaria de Santo Domingo, Ecuador

Esta investigación tuvo como objetivo indagar el estado de las fases de los procesos administrativos de las unidades de producción agropecuaria. Para ello, se planteó una investigación mixta-exploratoria en Santo Domingo, Ecuador. Los resultados demuestran que los emprendedores agropecuarios han ejecutado oportunamente la fase de dirección con los trabajadores, pero las fases de control y dirección son deficientes. Se concluye que la falta de control sobre los resultados genera que, de manera general, estos emprendimientos posean procesos administrativos subdesarrollados. Palabras clave: Proceso administrativo, Emprendimientos agropecuarios, Gestión de Empresas ABSTRACT:
Sheltered employment in schizophrenia is related to disorganization symptoms, processing speed and metaphor comprehension.

OBJECTIVES The significance of cognitive functioning deficits in schizophrenia is already well acknowledged. The relationships among lower and higher order cognitive skills and symptoms, as well as their relevance to holding a paid job are relatively less researched, though. The purpose of this study was to conduct an analysis concerning these issues. METHODS This study included 62 individuals with schizophrenia, 33 of them employed in paid sheltered jobs and 29 attending occupational therapy. They were assessed with tests of cognitive functions including communication skills. Psychopathological symptoms were assessed with the PANSS. RESULTS The assessed cognitive skills turned out to be interrelated as well as showed associations with positive, negative and disorganization symptoms. Furthermore, regression analysis showed that sheltered employment status is predicted by shorter reaction time, better comprehension of metaphors and lower severity of disorganization symptoms. CONCLUSIONS Multiple associations among basic and higher cognitive skills provide support for the concept of a generalized cognitive dysfunction in schizophrenia. Beside psychopathology symptoms, both basic and higher cognitive skills are also independently predictive of professional functioning in schizophrenia. This suggests potential areas of cognitive rehabilitation that could affect employability.
Perspective: The Moral Distress Debate

‘What is ‘‘moral distress’’ in nursing? ’ This was the question we explored in May 2016 at the Wellcome Collection, and also the first question I address in my doctoral thesis. My second question is normative. I ask, in light of nurses’ experiences of moral distress, ‘How should we respond to it? ’. The project is funded by a Wellcome Trust Society and Ethics Fellowship and is an empirical ethics project in which I aim to develop a robust conceptualisation of moral distress and conduct ethical analysis that considers the most appropriate way to respond to it. Moral distress has been defined in many ways since the American philosopher Andrew Jameton introduced the concept to nursing just over 30 years ago. Jameton (1984: 6) defined moral distress as arising ‘when one knows the right thing to do, but institutional constraints make it nearly impossible to pursue the right course of action’. Moral distress has since grown as a topic of interest and multiple definitions have been suggested. However, very few explore the concept in a UK context and it remains a relatively unknown concept in the UK. The aim of the event was to increase awareness of the concept, debate its meaning and discuss its importance. In my mind, the latter question was answered by acknowledgement from the audience of the impact that complex moral issues faced daily by healthcare professionals have. The eclectic audience was engaged and interactive throughout the debate, and I think this demonstrates the strength of feeling that moral distress can create amongst professionals and patients alike. We were fortunate to have an excellent panel of speakers, comprising: Jill Maben, OBE, Professor of Nursing Research at King’s College London; Ann Gallagher, Professor of Ethics and Care at the University of Surrey; John Paley, previously visiting fellow at Sheffield Hallam University, Health and Social Care Research; and Lesley Baillie, Professor of Nursing, London South Bank University and Florence Nightingale Foundation Chair. The panel and discussion were expertly chaired by Deborah Bowman, Professor of Clinical and Mental Health Ethics at The Tavistock and Portman NHS Foundation Trust and regular commentator on BBC Radio 4’s ‘Inside the Ethics Committee’.
Characterizing Disagreement in Online Political Talk: Examining Incivility and Opinion Expression on News Websites and Facebook in Brazil

This article examines the ways people engage in political conversation triggered by exposure to political news in two different informal platforms in Brazil: Facebook and news websites. We analyze the extent to which disagreement is associated to discursive traits that are commonly associated with deliberative behavior, such as directly engaging with others, and trying to justify one’s views, and negative traits, such as incivility. The contributions of this article can be summarized as follows. First, this article emphasizes the importance of looking beyond a single platform and a single topic to understand political discussion online. Second, we demonstrate that online disagreement is positively associated with both deliberative traits, such as justified opinion expression, and nondeliberative traits, such as incivility, and argue that the latter is not enough to dismiss the value of political talk. We also demonstrate that the topic of a news story is relevant both to drive political conversation and to spark political disagreement: controversies involving celebrities and stories covering international affairs are more likely to drive heterogeneous conversations than more conventional political topics (e.g., government, policy), even though these are the topics that tend to attract more political talk. Finally, this study contributes to fill an important gap in the literature, looking beyond the United States and Western European contexts by examining political talk in Brazil, the fourth largest digital market in the world.
Using a Down‐Looking Multifrequency ABS for Measuring Suspended Sediments in Rivers

In the last decade, much progress has been made in continuously measuring suspended sediment concentration (SSC) in rivers using horizontal side‐looking Acoustic Doppler Current Profilers. However, these techniques do not provide information on the spatial variability of the suspension. In this study, we explore some new possibilities offered by the down‐looking deployment of a multifrequency acoustic backscatter system (ABS) in order to obtain information on the suspension throughout an entire river cross section. Two sites, with low and high levels of SSC, were investigated. The acoustic signal was processed using multifrequency inversion methods. Both water sample calibration data and modeling were used for retrieving the acoustic properties of the suspended particles. At the low SSC site ( ∼ 30 mg/L), we successfully inverted the acoustic signal, except in some areas of high acoustic backscatter close to the surface that were probably generated by air microbubbles. At the high SSC site ( ∼ 10 g/L), estimates of both fine and sand SSCs throughout the river cross section were successfully obtained, except in some areas close to the bottom where the acoustic signal was totally attenuated due to distance and high concentration of fine sediments. This work confirms the capacity of hydroacoustic technology for providing spatial information on river suspensions.
New Candidate Ultralow-Velocity Zone Locations from Highly Anomalous SPdKS Waveforms

Ultralow-velocity zones (ULVZs) at the core–mantle boundary (CMB) represent some of the most preternatural features in Earth’s mantle. These zones most likely contain partial melt, extremely high iron content ferropericlase, or combinations of both. We analyzed a new collection of 58,155 carefully processed and quality-controlled broadband recordings of the seismic phase SPdKS in the epicentral distance range from 106° to 115°. These data sample 56.9% of the CMB by surface area. From these recordings we searched for the most anomalous seismic waveforms that are indicative of ULVZ presence. We used a Bayesian approach to identify the regions of the CMB that have the highest probability of containing ULVZs, thereby identifying sixteen regions of interest. Of these regions, we corroborate well-known ULVZ existence beneath the South China Sea, southwest Pacific, the Samoa hotspot, the southwestern US/northern Mexico, and Iceland. We find good evidence for new ULVZs beneath North Africa, East Asia, and north of Papua New Guinea. We provide further evidence for ULVZs in regions where some evidence has been hinted at before beneath the Philippine Sea, the Pacific Northwest, and the Amazon Basin. Additional evidence is shown for potential ULVZs at the base of the Caroline, San Felix and Galapagos hotspots.
Who patents, how much is real invention and how relevant? A snapshot of firms and their inventions based on the 2016 SIPO China Patent Survey

China has surpassed the United States in patent applications and has become world leader. Strong patenting activity, however, did not lead to strong productivity growth. The delinking of patenting activity from productivity growth could be explained by quality and relevance issues. Although the number of patents has been soaring, few are genuine inventions. Relatively low utilisation rates of patents point to a low degree of relevance. This paper uses a representative survey of Chinese patenting firms to provide a detailed picture of the patenting landscape along the dimensions of geographical areas, detailed industrial sectors, traditional and modern industries as defined by the Chinese government, firm age, size and ownership. It also overviews government subsidies across firms. Transport equipment makers hold most patents per firm, followed by electronics manufacturers. State-owned firms spend more on R&D per patent, but hold fewer patents per researcher than private or foreign-invested firms. High patenting performance and government support are not necessarily linked to high utilisation of patents. Smaller, younger and private firms expect a higher return on their patents and so do exterior design patent holders. Furthermore, the paper examines what drives patenting activity. Higher R&D spending by the firm and higher share of researchers in its workforce tend to be associated with higher patents per employee. Smaller and older firms tend to patent more, and government support also appears to matter. Exterior design patents are associated with different firm characteristics: R&D intensity is lower and government support matters less. Most firms consider IPR protection insufficient and the share of firms having experienced patent infringement is the greatest among the largest firms. Many of them do not do anything once their rights are infringed as they do not expect effective remedy. Instead of patenting, which may not provide sufficient protection from imitators, they adopt other strategies like reaping the first mover advantage to market their goods or sign confidentiality agreements with their staff or contracts on commercial secrets. This Working Paper relates to the 2019 Economic Survey of China (http://www.oecd.org/economy/china-economic-snapshot/).
Decreased RNase Activity Under High Temperature Is Related to Promotion of Self-pollen Tube Growth in the Pistil of the Japanese Flowering Cherry, Prunus × yedoensis ‘Somei-yoshino’

Prunus × yedoensis Matsum. ‘Somei-yoshino’ is one of the most popular flowering cherry cultivars in Japan. However, because flowering cherries have strict self-incompatibility (SI), it is difficult to develop selfing families or inbred lines for breeding and genetic studies. SI in Prunus is achieved through arrest of self-pollen tube growth in the style by ribonuclease S-RNase. To determine a suitable way to overcome SI in Prunus , we examined the influence of hot water immersion on RNase activity in the style of ‘Somei-yoshino’. When the styles were immersed in 20°C, 30°C, and 40°C water baths, their RNase activity was not significantly different from that of untreated styles ( P > 0.05); however, it significantly decreased in styles heated in 50°C water baths ( P < 0.01). Furthermore, the RNase activity decreased with an increase in the incubation time (e.g., 1, 3, and 5 min). Additionally, heat treatment at 50°C promoted the growth of self-pollen tubes in the style. Some self-pollen tubes even reached the bottom of the style. The high temperature treatment with reduced RNase activity can overcome stylar SI in Prunus .
A density functional theory outlook on the possible sensing ability of boron nitride nanotubes and their Al- and Si-doped derivatives for sulfonamide drugs

ABSTRACT In this study, the adsorption behavior of boron nitride nanotubes (BNNTs) and their Al- and Si-doped BNNTs toward sulfonamide (SA) drugs is explored using density functional theory (DFT) calculations. Total energies, geometry optimizations, frontier molecular orbital (FMO) and density of state (DOS) analyses were obtained using M06-2X level of theory and the 6-311G(d) basis sets. In the most stable conformation, adsorption energies of the sulfonamide molecule over pristine BNNTs, Al-BNNTs, Si-BNNTs are 25.9, 59.7 and 51.7 kcal/mol, respectively. The HOMO–LUMO gap, Eg, which corresponds to sensing ability, is the most for pristine BNNTs toward SA indicating that BNNTs can be a promising candidate for sensing SA. On the other hand, Al-BNNTs and Si-BNNTs cannot used for sensing SA. GRAPHICAL ABSTRACT
Trading Imbalance, Liquidity and Stock Returns: Evidence from Brazil

Abstract The present study investigates empirically whether trading imbalances affect cross-sectional stock returns in the Brazilian market. This question is particularly important in emerging markets, where there is strong evidence that order flows of institutional investors are persistent. The main contribution of this study is to price the effect of intraday imbalances through a variable that we call TIP (Trading Imbalance Picture) in an asset pricing regression. The analysis is carried out considering variations for enhanced corporate governance listing segments, economic sectors, and risk factors. The results suggest that trading imbalance strongly predicts stock returns in the cross-section, even after accounting for risk factors, firm characteristics and other liquidity measures, and a daily difference of 1% in TIP among stocks translates into a difference in required return of 6.96% per year.
A phase 1B, open-label, dose-escalation study of bortezomib in combination with gemcitabine (Gem) and cisplatin (Cis) in the first-line treatment of patients with advanced solid tumors: Preliminary results of a phase IB study

2103 Background: Bortezomib (VELCADE) is a reversible and specific inhibitor of the 26S proteasome. Gem/Cis is an accepted first-line treatment for several advanced solid tumors. This trial aims to determine MTD and investigate tolerability of a weekly and biweekly schedule of bortezomib in combination with Gem/Cis. Methods: Chemotherapy-naive patients (KPS ≥ 70%) with advanced solid tumors for whom first-line Gem/Cis was considered an acceptable therapeutic option received Gem 1000 mg/m2 on days 1 and 8 and Cis 70 mg/m2 on day 1 of a 21-day cycle. In the weekly schedule, bortezomib was administered on days 1 and 8 at 1.0, 1.3, or 1.6 mg/m2. In the biweekly schedule, bortezomib was administered on days 1, 4, 8, and 11 at 0.70, 1.0, or 1.3 mg/m2. Results: 13 pts have been treated for at least 1 cycle: 7 on the weekly schedule (3 pts at 1.0 mg/m2 and 4 pts at 1.3 mg/m2) and 6 on the biweekly schedule (3 pts at 0.7 mg/m2 and 3 pts at 1.0 mg/m2). Median age: 53 y (range, 35–71); male/female = 9/4; KPS .
Effect of adenosine concentration on quality of cooled ram semen

ABSTRACT This study analyzed the adenosine concentration on quality of ram semen in different refrigerated storage times at 5 °C. The design was in blocks with repeated-measures factorial design. Five levels of adenosine and four refrigeration times were considered as fixed effects and the animal as random effect (block). Ram semen was diluted with Andromed® diluent (control) and increasing adenosine levels (0.5, 0.75, 1, and 1.5%). The samples were taken from refrigeration after 4, 8, 12, and 16 h and [. ]
A clinical and genetic study of the skeletal muscle channelopathies

The skeletal muscle channelopathies are a group of inherited muscle diseases characterised by the abnormal functioning of voltage-gated ion channels expressed in skeletal muscle. They manifest as the non-dystrophic myotonias and the periodic paralyses. This thesis increases the current understanding of the clinical and genetic basis of this group of diseases. It identifies the overall prevalence in England as 1.12/100,000 and determines the individual minimum prevalence of each disease, which has not previously been documented. It presents a detailed phenotype study of periodic paralysis (PP), paramyotonia congenita (PMC) and sodium channel myotonia (SCM), which is the first comparative study of these diseases. In the process it uncovers the marked similarity between PMC and SCM and suggests that these may be a spectrum of one disease, rather than two distinct diseases as traditionally thought. It provides the first systematic study of pregnancy and anaesthetics in a large number of channelopathy patients, identifying a marked increase in severity of symptoms during pregnancy that has not previously been documented. To widen the spectrum of genetic diagnosis and techniques in this group of diseases, this thesis describes the first cases of large scale rearrangements in CLCN1 causing myotonia congenita. It demonstrates how, using whole exome sequencing, the genetic diagnosis rate can be improved and illustrates two cases that may be explained by variations in RYR1 and another case in which a genetic diagnosis of Liddle’s syndrome may underlie secondary PP. This suggests that RYR1 variations may account for some unconfirmed cases and others may be explained by genetic causes of secondary PP. Finally this thesis presents convincing evidence of the efficacy of mexiletine in non-dystrophic myotonia in a double-blind placebo-controlled trial. It demonstrates improvement of the primary outcome measure of patient-reported stiffness and the majority of secondary outcome measures assessed.
Maintenance Rituximab after CVP Results in Superior Clinical Outcome in Advanced Follicular Lymphoma (FL): Results of the E1496 Phase III Trial from the Eastern Cooperative Oncology Group and the Cancer and Leukemia Group B.

E1496 is a phase III trial designed to evaluate the ability of 2 years (yr) of maintenance rituximab (MR) to prolong progression-free survival (PFS) after CVP (cyclophosphamide 1 G/m2 day [d] 1, vincristine 1.4 mg/m2 [max = 2 mg] d 1, prednisone 100 mg/m2 d 1–5) chemotherapy in stage III–IV follicular grade 1 and 2 and small lymphocytic lymphoma. After CVP treatment to maximum response, (6–8 cycles), stable and responding patients (pt) were randomized to MR (375 mg/m2 weekly x 4) every 6 months x 4 or observation (OBS). Stratification factors included histology, response and residual disease after CVP. With 3-yr median follow-up, survivals (from time of randomization, one-sided logrank p values) for all pt (n=304) favored MR for PFS (p = 3 x 10–8; hazard rate {HR} = 0.38 [0.28;0.54, 95% confidence intervals]) and OS (p = 0.09; HR = 0.66 [0.36–1.22]). Because the large majority of pt have FL and because rituximab efficacy is notably greater in FL, we focused in this report on the 237 FL pt. Median age was 58 yr, 65% were stage IV, 64% had marrow disease, 64% had high tumor burden and 37% had high-risk disease by the follicular lymphoma prognostic index. PFS after randomization was significantly longer for MR vs OBS (p = 3 x 10-7; HR = 0.39 [0.27;0.57]). The estimated PFS at 4 yr (~4.5 yr after start of treatment) was 56% for MR vs 33% for OBS. Differences in PFS were significant within the predefined strata and the differences were most significant in favor of MR for pt with high initial tumor burden and minimal residual disease after CVP. Overall survival was superior for MR (p = 0.03; HR = 0.51 [0.25;1.04]. Estimated OS at 4 yr (~4.5 years after start of treatment) was 88% for MR vs 72% for OBS. Of 33 deaths, 21 occurred on the OBS arm. These data demonstrate that maintenance rituximab not only significantly delays disease progression in FL compared with OBS but that a substantial proportion of patients treated with MR remain disease-free at 4 years after the completion of CVP. These are the first data to strongly suggest a survival benefit with a therapy that includes rituximab and CVP and the first to strongly suggest a survival benefit with maintenance rituximab in FL.