Miracle-dz/UniFAR-FTUs huggingface dataset:
PATIENT SATISFACTION WITH IMPLANT RETAINED PROSTHESIS PROVIDED BY RESIDENTS AT KING ABDULAZIZ UNIVERSITY- FACULTY OF DENTISTRY (KAUFD) AND KING FAHD ARMED FORCES HOSPITAL (KFAFH)

Aim: To evaluate patients’ satisfaction following treatment with implant supported prosthesis. Methods: 70 patients were requested to complete a standardized survey over the phone to rate their satisfaction following treatment with dental implants at King Abdulaziz UniversityFaculty of Dentistry (KAUFD) and King Fahd Armed Forces Hospital (KFAFH) that was provided by residents post graduates in the implant fellowship program. The questionnaire included patients general information, the location of the implant placed as well as the type of prosthesis provided and patients opinion with regards to cost, treatment duration and choice of treatment. Results: 30% of the patients received treatment at KFAFH, while 70% were treated at KAUFD 65.7% of the patients were employed with 39% of those working in the military sector. The treatment duration was reported to be less than one year in 57.1% of the cases. As for the location of the implant, most were placed in the posterior region (84.3%) and 52.9% were placed in the mandibular arch with 87% were restored using fixed prosthesis. Conclusion: A high percentage of patients were completely satisfied with implant therapy and would recommend it to others. The only complained was due to the lengthy appointments needed for treatment.
JPPE 23권1호_2차편집(0225).hwp

The purpose of this study was to investigate the effects of the horticultural therapy program on patients with mild cognitive impairment and mild dementia depending on the frequency and duration of the interventions. We developed the same 15-session program to improve cognitive functions and life satisfaction and alleviate depression of the elderly women with mild cognitive impairment or mild dementia. Subjects in Longer Treatment group participated in the program once a week for 15 weeks and subjects in Shorter Tratmet group participated twice a week for 71⁄2 weeks. This study conducted pretest-posttest verification of both groups using quasi-experimental design involving 21 subjects. Elderly life satisfaction, Geriatric Depression Scale (short form), and the Korean Version of Consortium to Establish a Registry of Alzheimer’s Disease (CERAD-K) were used in the evaluation. As a result, both groups showed an increase in life satisfaction, and a decrease in depression. However, there was a significant difference in the changes of the CERAD-K scores between the two groups (p < .05). In Longer Treatment group, life satisfaction increased significantly (p < .001), and depression decreased at a marginally significant level (p = .068), but no statistically significant change was observed in neurocognitive function. In Shorter Treatment group, life satisfaction increased at a marginally significant level (p = .059), and depression and CERAD-K scores decreased significantly (p < .05). However, in the case of Mini-Mental State Examination (MMSE-K), there was no significant change in both groups. According to these results, when planning a horticultural therapy program for persons with mild cognitive impairment or mild dementia, it is effective to organize and execute the program by determining the duration of intervention as 3 to 4 months or longer, even if this reduces the number of interventions per week.
The Expression of Programmed Death Ligand-1 within Stages of Oral Squamous Cell Carcinoma: Immunohistochemical Analysis

Background: Oral squamous cell carcinoma is prevalent in South Asian countries with rising cases of its incidence and mortality. Despite advancements in treatment, survival and recurrence rates are poor. Immunotherapy is a novel therapeutic modality in immunooncology. Immune checkpoint proteins are under investigation for clinical implications amongst which Programmed Death Ligand-1 has shown valuable results in certain malignancies. Aims: To determine the immunohistochemical expression of Programmed Death Ligand-1(PD-L1) in oral squamous cell carcinoma and to find an association of Programmed Death Ligand-1 with stage and clinicopathological parameters of oral squamous cell carcinoma. Study Design: Cross-sectional study. Place and Duration of Study: Ziauddin Medical University, Karachi, 1 Year duration during 20182019. Methods: A total number of 140 biopsy confirmed cases of oral squamous cell carcinoma were recruited in the study. Immunohistochemical expression of Programmed Death Ligand-1 was Original Research Article Khan et al.; JAMMR, 32(2): 59-68, 2020; Article no.JAMMR. 55165 60 evaluated and associated with the clinicopathological parameters of oral squamous cell carcinoma (OSCC). The data was statistically analyzed through Descriptive statistics and Chi square test by using SPSS v.20. Results: Out of 140 participants, 74% were males (n=103) and 26% were females (n=37). Programmed Death Ligand-1 positivity was observed in 62.1% of cases (n=87). The Mean age of the participants was 48.91 ± 11.7 years. The most common site of cancer involvement was buccal mucosa and majority of participants were habitual of consuming chewable products i.e. Pan, Gutka and betel nut (89; 64%). Stage III and IV tumours comprised a major portion of cases in our study. (52; 37%), (56; 40%). A statistically significant p-value was noted for the association of Programmed Death Ligand-1 with stage II and IV tumours. (P-values: 0.029, 0.001)The association of Programmed Death Ligand-1 with other variables such as age, gender, ethnicity, sites or habits was not statistically significant. Conclusion: This study concludes that the statistical significance of Programmed Death Ligand-1 expression with tumour stage is suggestive of worsening prognosis and might have detrimental effects as tumour progresses in advanced stage. Programmed Death Ligand-1 positivity in patients having oral squamous cell carcinoma could be useful in future research in the light of cancer immunotherapy which has shown success in oncology.
Prenatal maternal mood entropy is associated with child neurodevelopment.

Emerging evidence indicates that the predictability of signals early in life may influence the developing brain. This study examines links between a novel indicator of maternal mood dysregulation, mood entropy, and child neurodevelopmental outcomes. Associations between prenatal maternal mood entropy and child neurodevelopment were assessed in 2 longitudinal cohorts. Maternal mood was measured several times over pregnancy beginning as early as 15 weeks' gestation. Shannon's mood entropy was applied to distributions of mothers' responses on mood questionnaires. Child cognitive and language development were evaluated at 2 and 6-9 years of age. Higher prenatal maternal mood entropy was associated with lower cognitive development scores at 2 years of age and lower expressive language scores at 6-9 years of age. These associations persisted after adjusting for maternal pre and postnatal mood levels and for other relevant sociodemographic factors. Our findings identify maternal mood entropy as a novel predictor of child neurodevelopment. Characterizing components of maternal mood in addition to level of severity or valence may further our understanding of specific processes by which maternal mood shapes child development. (PsycInfo Database Record (c) 2020 APA, all rights reserved).
Grant Report on Social Reward Learning in Schizophrenia †

We report on the ongoing R21 project “Social Reward Learning in Schizophrenia”. Impairments in social cognition are a hallmark of schizophrenia. However, little work has been done on social reward learning deficits in schizophrenia. The overall goal of the project is to assess social reward learning in schizophrenia. A probabilistic reward learning (PRL) task is being used in the MRI scanner to evaluate reward learning to negative and positive social feedback. Monetary reward learning is used as a comparison to assess specificity. Behavioral outcomes and brain areas, included those involved in reward, are assessed in patients with schizophrenia or schizoaffective disorder and controls. It is also critical to determine whether decreased expected value (EV) of social stimuli and/or reward prediction error (RPE) learning underlie social reward learning deficits to inform potential treatment pathways. Our central hypothesis is that the pattern of social learning deficits is an extension of a more general reward learning impairment in schizophrenia and that social reward learning deficits critically contribute to deficits in social motivation and pleasure. We hypothesize that people with schizophrenia will show impaired behavioral social reward learning compared to controls, as well as decreased ventromedial prefrontal cortex (vmPFC) EV signaling at time of choice and decreased striatal RPE signaling at time of outcome, with potentially greater impairment to positive than negative feedback. The grant is in its second year. It is hoped that this innovative approach may lead to novel and more targeted treatment approaches for social cognitive impairments, using cognitive remediation and/or brain stimulation.
Effect of mindfulness meditation protocol in subjects with various psychometric characteristics at high altitude

Incidence of high altitude‐related sickness is increasing due to more number of people visiting the areas of high altitude which may result in life‐threatening conditions including acute mountain sickness (AMS), high altitude pulmonary edema (HAPE), high altitude cerebral edema (HACE), and High‐altitude pulmonary hypertension (HAPH). We hypothesized that an advanced yoga regimen may be beneficial in dealing with the physiology of acclimatization.
Polyether ionophores residues in Minas Frescal cheese by UHPLC-MS/MS

ABSTRACT An analytical method was developed and validated for the determination of three polyether ionophores (monensin, lasalocid, and salinomycin) in 60 samples of Brazilian Minas Frescal cheese by UHPLC-MS/MS. Linearity ranged from 1 to 8 μg kg−1 for monensin and salinomycin, and from 0.50 to 4 μg kg−1 for lasalocid. Limits of detection and quantitation were 0.50 μg kg−1 and 1 μg kg−1, respectively, for both monensin and salinomycin, and 0.25 μg kg−1 and 0.50 μg kg−1, respectively, for lasalocid. Recoveries were between 69% and 84% with coefficients of variation up to 16.28% for repeatability and 13.79% for intermediate precision. A total of 60 samples of Minas Frescal cheese were analysed and only monensin residues were found. Monensin was detected in 55% of the samples and quantified in 5 of them at mean levels varying from 1.00 to 1.73 μg kg−1. The proposed method demonstrated the suitability for monitoring these substances in cheese.
Comparing the use of propofol and thiopental and their admixturefor laryngeal mask airway (LMA) insertion

Comparing the use of propofol and thiopental and their admixturefor laryngeal mask airway (LMA) insertion (Article) Yazdi, B.a, Talebi, H.a, Modir, H.a, Dadashpour, N.b, Khabiri, M.c, Eraghi, M.G. d a Department of Anesthesiology, Arak University of Medical Sciences, Arak, Iran b Department of Anesthesiology, Lorestan University of Medical Sciences, Khoram abad, Iran c Anesthesiology Research Center, Department of Anesthesiology, Taleghani, Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran View additional affiliations View references (18) Abstract Introduction and purpose: Propofol and thiopental are two common medications used for anesthesia induction with different pharmacologic and pharmacodynamic effects. The purpose of this study is to compare the effect of propofol and thiopental and their admixture on hemodynamic status and ease of LMA insertion. Methodology: This study was performed on 138 non-emergency patients. Samples were randomly divided into three 46-member groups who received propofol solution, propofol and thiopental admixture and thiopental solution. Next, the above admixtures were randomly injected. During the first 30 seconds, each patient was ventilated and then LMA insertion was performed. Patients' reaction to the occurrence or non-occurrence of the gagreflex, coughing, limb and head movement and laryngospasm were registered. Heart rate and blood pressure in patients before induction, immediately after injection and then with 2 minute intervals until the restart of breathing were registered. Results: There was a remarkable difference in patient reaction after LMA insertionin the propofol and thiopental admixture group. There was a significant statistical difference between the three groups in terms of limb and head movement (P≤0.002), coughing (P≤0.033), the gag reflex (P 0.05). Conclusion: The effects created on hemodynamics, patient reaction after LMAinsertion and other reactions during anesthesia in the propofol and thiopental admixture group were lower and it provides better conditions in anesthesia with an LMA. © 2016, International Journal of Pharmacy and Technology. All rights reserved. Author keywords Hemodynamic changes; Laryngeal mask; Propofol; Thiopental
Relationships between Change of Direction, Sprint, Jump, and Squat Power Performance

The aim of the study was to investigate the relationships between countermovement jump (CMJ) height and inertial power in squat and sprint variables with change of direction (COD) performance. Fifty young healthy active males participated in the study. To determine these relationships, we carried out a 10-m linear sprint test (T 10 m), vertical jump tests (CMJ and CMJ Abalakov), an assessment of power relative to bodyweight in a flywheel squat (Pbw), and 10-m COD sprints with two different turn types (COD-90° and COD-180°). T10 m showed statistically large and moderate correlations with T10 m COD-180° (r = 0.55) and T10-m COD-90° (r = 0.41), respectively. Moderate to large correlations between jumping height, linear sprinting, and sprints with COD were found (r = −0.43 to r = −0.59), and there were unclear correlations between jumping height and the loss of speed caused by executing COD (DEC-COD). Pbw showed a large correlation with CMJ Abalakov and CMJ jump height (r = 0.65 and r = 0.57, respectively), and a moderate and large correlation with T 10 m, T 10 m COD-180°, and T10 m COD-90° (r = −0.33, r = −0.38, and r = −0.54, respectively). Despite the existence of substantial correlations between variables, straight linear sprinting, jumping performance, CODs and squat power were, for the most part, separate motor qualities (R2 from 14% to 34%), suggesting that all of them should be specifically assessed and trained.
Normalization of Forefoot Supination After Tibialis Anterior Tendon Transfer for Dynamic Clubfoot Recurrence

Supplemental Digital Content is available in the text. Background: We aimed to evaluate the effect of tibialis anterior tendon transfer (TATT) on foot motion in children with clubfoot recurrence after initial Ponseti treatment. Methods: Children with dynamic clubfoot recurrence after initial Ponseti treatment who underwent TATT between 2014 and 2017 were considered for inclusion. Exclusion criteria were neurological disease, split transfer of the tendon, additional bone or joint invasive surgery, and initial treatment abroad. Of 94 children (143 TATT), 36 met the inclusion criteria. Seventeen (47%) of the 36 children with 25 clubfeet and a mean age at the time of surgery of 6.8 years participated in the study. Gait analysis, including the Oxford foot model, was conducted preoperatively and postoperatively. Furthermore, kinematic and kinetic data were compared with those of age-matched healthy children (n=18). Results: Forefoot supination in relation to the hindfoot and tibia was reduced during swing and at initial contact after TATT compared with preoperative values. Forefoot supination in relation to the tibia at initial contact decreased from 12.4 to 5.2 degrees after TATT (control group, 6.0 degrees). The heel showed less dynamic varus and adduction movement after TATT compared with preoperatively. Maximum ankle power was reduced preoperatively and postoperatively compared with controls. Maximum ankle dorsiflexion slightly increased after TATT. Conclusions: Gait analysis showed normalization of the main components of dynamic clubfoot recurrence after TATT. This joint-sparing surgery efficiently corrects recurrent dynamic deformity. Level of Evidence: Level II—therapeutic.
The Incidence of Post-Electroconvulsive Therapy Headache

Supplemental digital content is available in the text. Abstract Headache is a common side effect of electroconvulsive therapy (ECT), but reports on its incidence vary widely. A broad array of treatment regimens have been proposed in the literature. The pathophysiology of post-ECT headache is unclear but a vascular origin has been suggested. A systematic literature search was executed in PubMed and Embase to identify relevant articles. Articles were screened on title, abstract, and full text according to predefined inclusion and exclusion criteria. Study characteristics and results concerning the incidence of post-ECT headache were extracted, and a weighted mean incidence was calculated. Forty-seven relevant articles were found, of which 36 reported on the incidence of post-ECT headache in patients and 9 on the incidence in sessions. The incidence of post-ECT headache varied greatly in the literature. The weighted mean incidence in patients was 32.8%, as 786 of a total population of 2399 patients experienced headache. The weighted mean incidence in sessions was between 9.4% (246 of 2604 sessions) and 12.1% (236/1958 sessions). The variation in incidences of post-ECT headache found might be due to different methods of measuring headache, different study designs, and different drugs used for anesthesia. The mean-weighted incidence of post-ECT headache in patients was 32.8% and in sessions between 9.4% and 12.1%.
Pharmacologic and Genetic Manipulations of Angiotensin Signaling in Thoracic Aortic Disease Models

-----------------------------------------------------------------------------------------------------vi Table of contents ------------------------------------------------------------------------------------------ix List of figures ----------------------------------------------------------------------------------------------xiii List of tables -----------------------------------------------------------------------------------------------xv List of abbreviations -------------------------------------------------------------------------------------xvi Chapter 1: Introduction -------------------------------------------------------------------------------------1 1.1 Structure of the aorta -------------------------------------------------------------------------2 1.2 Thoracic aortic disease and pathology ------------------------------------------------------7 1.3 Angiotensin system ----------------------------------------------------------------------------12 1.4 Angiotensin in animal models ----------------------------------------------------------------14 1.5 Hypothesis tested ------------------------------------------------------------------------------17 Chapter 2: Methods ------------------------------------------------------------------------------------------18
Elective surgery should be considered after successful conservative treatment of recurrent diverticular abscesses

Abstract Purpose: The purpose of this study was to evaluate the disease pattern and treatment of diverticular abscesses. Methods: Patients treated for diverticulitis (K57) in Västmanland, Sweden were identified for this retrospective population-based study between January 2010 and December 2014. Patients with diverticular abscesses were included. The clinical and radiological data were extracted, and the computed tomography scans were reevaluated. Results: Of the 75 patients (45 women) with a median age of 62 years (range: 23–88 years), abscesses were localized pericolic in 42 patients (59%) and in the pelvis in 33 patients (41%). The median abscess size was 4.8 cm (range: 1.1–11.0 cm). Six patients (8%) required urgent surgical intervention during the index admission. The median follow-up time was 58 months (range: 0–95 months). During follow-up, 40 patients (58%) had disease recurrence and 35 of these patients (88%) presented with complicated diverticulitis. The median time until re-admission was 2 months (range: 3 days–94 months). Patients with pelvic abscesses developed fistulas more frequently, 3 versus 11 patients (p = .003). Twenty-three percent of patients with pericolic abscesses required surgery compared with 40% of patients with pelvic abscesses (p = .09). No patients had a recurrence of abscesses after a colonic resection. Conclusion: The majority of patients with diverticular abscesses had recurrences with repeated admissions regardless of abscess location. An unexpectedly high proportion of patients required surgical intervention during the follow-up period. A liberal approach regarding elective surgery for patients with recurrent diverticulitis abscesses who tolerate surgery seems justified.
Fixed/Preassigned-Time Synchronization of Complex Networks via Improving Fixed-Time Stability

This article is concerned with the problem of fixed-time (FXT) and preassigned-time (PAT) synchronization for discontinuous dynamic networks by improving FXT stability and developing simple control schemes. First, some more relaxed conditions for FXT stability are established and several more accurate estimates for the settling time (ST) are obtained by means of some special functions. Based on the improved FXT stability, FXT synchronization for discontinuous networks is discussed by designing a simple controller without a linear feedback term. Besides, the PAT synchronization is also explored by developing several nontrivial control protocols with finite control gains, where the synchronized time can be prespecified according to actual needs and is irrelevant with any initial value and any parameter. Finally, the improved FXT stability and the synchronization for complex networks are confirmed by two numerical examples.