Miracle-dz/UniFAR-FTUs huggingface dataset:
Urban sustainable development and the challenge of French metropolitan strategies

This article focuses on some salient issues of urban sustainable development in France, specifically with regard to six urban agglomerations: Bordeaux, Lille, Lyon, Montpellier, Nantes and Toulouse. The reticular dimension of these issues is analysed with reference to the ways a plurality of actors imagine, project and realize the construction of cities, rather than through sectoral points of view. This relational approach is divided according to a triple focus in which we successively address: firstly, the state of Sustainable Development (SD) policies in the six major cities, in terms of contents and conception; secondly, their implementation from the perspective of instruments; and finally, the circuits of their realization. Thus, urban SD appears within a (locally variable) set of linkages that place these issues firmly in areas of interrelations and intersections.
Editorial: Immune evasion mechanisms and their role in the pathogenesis of autoimmune disorders

COPYRIGHT © 2023 Rizzo and Houen. This is an openaccess article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. TYPE Editorial PUBLISHED 13 September 2023 DOI 10.3389/fimmu.2023. 1267922
A Q-Methodology of Preservice Teachers’ Cognition of Digital Literacy: A Philippine Case Study in Resource-Rich and Resource-Limited Settings

: This study aims to determine the existing digital literacy notions of Filipino preservice in two universities: one is a resource-rich context while the other is a resource-limited context. Contexts were determined based on the observed availability of digital tools. Twenty (20) preservice teachers each from two universities were invited for interviews after which they were again requested to arrange statements culled from the interviews. Utilizing the Q-sort methodology, a method that determines the standpoints of participants by their ranking of statements, three dimensions were identified: the portrait of balance, portrait of responsibility and portrait of support. The portraits represent the themes identified after participants determined the ranking of their statements. As evidenced on the results, the pre-service students in the resource-rich context identified themselves with the portrait of support and responsibility while those from the resource-limited context concentrated heavily on the portrait of balance. The differences in the viewpoints identified how the preservice teachers’ access to resources has impacted their cognition of digital literacy.
Epidemiology of confirmed measles virus cases, surveillance, incidence, and associated factors in Eritrea: 18-year retrospective analysis

Background Despite the outstanding measles vaccine coverage (MVC) in Eritrea, sporadic outbreaks are not uncommon. Therefore, understanding the incidence of laboratory-confirmed measles virus cases, related factors, and spatial inequalities in testing and surveillance remains crucial. In this analysis, we evaluated the incidence and spatiotemporal distribution of measles in Eritrea. An evaluation of the factors associated with measles vaccination and IgM positive (+) febrile rash was also undertaken. Methods A retrospective (period: 2002–2020) study was carried out by abstracting data from the integrated disease surveillance and response database (IDSR). Data was analyzed using descriptive statistics and binary logistic regression. Spatial variability and distribution of confirmed cases was evaluated using ArcGIS Pro version 3.0. 1. Results In total, 9,111 suspected cases, 2,767 [1,431 (51.7%) females] were serologically tested. The median (IQR) age, minimum-maximum age were 7 years (IQR: 4–14 years) and 1 month-97 years, respectively. Among the 608(21.9%) laboratory-confirmed cases, 534 (87.8%) were unvaccinated and 53 (9.92%) were < 1 year old. The crude incidence rate for MV was 14/100,000 persons. The age-specific positivity rate per 100,000 suspected cases tested was 21.5 with individuals >30 years presenting with the highest rates (69.9/100,000). Higher odds (OR) of MV test positivity was associated with age at onset – higher in the following age-bands [10–14 years: OR = 1.6 (95%CI, 1.1–2.2, value of p = 0.005); 15–29 years: OR = 7.0 (95%CI, 5.3–9.2, value of p = 0.005); and > =30 years: OR = 16.7 (95%CI, 11.7–24) p < 0.001]. Other associations included: Address – higher in Anseba (OR = 2.3, 95%CI: 1.7–3.1, value of p<0.001); Debub (OR = 2.7, 95%CI: 1.9–3.9, value of p < 0.001); Gash-Barka (OR = 15.4, 95%CI: 10.9–21.7, value of p < 0.001); Northern Red Sea (OR = 11.8, 95%CI: 8.5–16.2, value of p < 0.001); and Southern Red Sea (OR = 14.4, 95%CI: 8.2–25.2, value of p < 0.001). Further, test positivity was higher in health centers (OR = 2.5, 95%CI: 1.9–3.4, value of p < 0.001) and hospitals (OR = 6.8, 95%CI: 5.1–9.1, value of p < 0.001). Additional factors included vaccination status - higher in the unvaccinated (OR = 14.7, 95%CI: 11.4–19.1, value of p < 0.001); and year of onset of rash – (higher >2015: OR = 1.4, 95%CI: 1.1–1.7, value of p<0.001). Uptake of measles vaccine associated with a similar complement of factors. Conclusion In large part, efforts to eliminate measles in Eritrea are hindered by disparities in vaccine coverage, under-surveillance, and low vaccination rates in neighboring countries. Enhanced surveillance and regional micro planning targeting hard-to-reach areas can be an effective strategy to improve measles elimination efforts in Eritrea.
Biomarkers of Alzheimer’s Disease and Cerebrovascular Disease in Relation to Depressive Symptomatology in Individuals With Subjective Cognitive Decline

Abstract Background Subjective cognitive decline (SCD) has gained recent interest as a potential harbinger of neurodegenerative diseases such as Alzheimer’s disease (AD) and cerebrovascular disease (CVD). In addition, SCD can be related to depressive symptomatology. However, the association between AD and CVD biomarkers, depressive symptomatology, and SCD is still unclear. We investigated the association of AD and CVD biomarkers and depressive symptomatology with SCD in individuals with subjective memory complaints (SCD-memory group) and individuals with subjective concentration complaints (SCD-concentration group). Methods We recruited a population-based cohort of 217 individuals (all aged 70 years, 53% female participants, 119 SCD-memory individuals, 23 SCD-concentration individuals, and 89 controls). AD and CVD were assessed through cerebrospinal fluid levels of the Aβ42/40 ratio and phosphorylated tau, and white matter signal abnormalities on magnetic resonance imaging, respectively. Associations between biomarkers, depressive symptomatology, and SCD were tested via logistic regression and correlation analyses. Results We found a significant association between depressive symptomatology with SCD-memory and SCD-concentration. Depressive symptomatology was not associated with AD and CVD biomarkers. Both the phosphorylated tau biomarker and depressive symptomatology predicted SCD-memory, and the Aβ42/40 ratio and depressive symptomatology predicted SCD-concentration. Conclusions The role of depressive symptomatology in SCD may differ depending on the stage within the spectrum of preclinical AD (as determined by amyloid-beta and tau positivity), and does not seem to reflect AD pathology. Our findings contribute to the emerging field of subclinical depressive symptomatology in SCD and clarify the association of different types of subjective complaints with distinct syndromic and biomarker profiles.
Age and workplace deviance

In the current meta-analysis, we examine the relation between age and workplace deviance, and find a small but significant negative correlation ( ρ = −.124, k = 198). More importantly, we test several trait-based mechanisms to help explain this relation. Specifically, based on the neo-socioanalytical model of personality change, we hypothesized that those Big Five personality traits that change with age, HEXACO honesty–humility, and trait negative affect mediate this relation. These hypotheses were supported, as the Big Five traits conscientiousness, agreeableness, and neuroticism, as well as honesty–humility and trait negative affect simultaneously mediated the negative relation between age and workplace deviance. These findings highlight important underlying mechanisms for this relation and suggest several opportunities for organizations to reduce the occurrence of workplace deviance. Further theoretical and practical implications as well as limitations and future research ideas are discussed.
Temporal and spatial properties of vestibular signals for perception of self-motion

It is well recognized that the vestibular system is involved in numerous important cognitive functions, including self-motion perception, spatial orientation, locomotion, and vector-based navigation, in addition to basic reflexes, such as oculomotor or body postural control. Consistent with this rationale, vestibular signals exist broadly in the brain, including several regions of the cerebral cortex, potentially allowing tight coordination with other sensory systems to improve the accuracy and precision of perception or action during self-motion. Recent neurophysiological studies in animal models based on single-cell resolution indicate that vestibular signals exhibit complex spatiotemporal dynamics, producing challenges in identifying their exact functions and how they are integrated with other modality signals. For example, vestibular and optic flow could provide congruent and incongruent signals regarding spatial tuning functions, reference frames, and temporal dynamics. Comprehensive studies, including behavioral tasks, neural recording across sensory and sensory-motor association areas, and causal link manipulations, have provided some insights into the neural mechanisms underlying multisensory self-motion perception.
A model to predict the bacterial quality of a rangeland stream

approved: James A. Moore Grazing cattle usually have access to streams as a source of drinking water. A model was developed for the personal computer to predict the bacterial quality of these streams. The model estimates the number of organisms that enter the stream by the direct deposit of feces and by runoff from rainfall or melting snow. The model also predicts the fate of these organisms upon entering the stream. The stream discharge rates can be calculated by the model or input by the user. The bacterial water quality is determined by the number of organisms suspended in the stream per volume of discharge. The model results were compared with bacterial levels measured in four different research projects and found to be within an order of magnitude in most cases. These results demonstrate that the model can predict bacterial concentrations with sufficient accuracy to make management decisions to insure a predetermined level of water quality. These results also demonstrate that the model is a better predictive tool for stream bacterial counts than traditional water sampling programs due to the model's ability to predict bacterial levels given a wide variety of grazing and hydrologic conditions. Redacted for Privacy The model was developed and tested using the most current research in rangeland water quality. As with any model, the accuracy of the results depend upon the accuracy of the input data. Future research can improve the usefulness of the model to better predict the bacterial counts in extended stream reaches. A Model to Predict the Bacterial Quality of a Rangeland Stream
Print Book and e-Book Collections in Academic Libraries in Malawi

Abstract Arrival of e-books on the scene has had a significant effect on the collection development activities of many academic libraries. Whilst some libraries have made the radical decision to ditch print books in favor of e-books, others are cautiously navigating the new terrain by acquiring both. The current study used the survey research design to study the collection development trends of print books and e-books in academic libraries in Malawi. The study found that academic libraries in Malawi are acquiring both print books and e-books. The trend has resulted from collection development decisions, practices, and budgetary constraints.
MCP1 Inverts the Correlation between FGF23 and Omega 6/3 Ratio: Is It Also True in Renal Transplantation?

During chronic kidney disease (CKD) progression, an increase in fibroblast growth factor (FGF23) is present. In stage 5, a positive correlation between FGF23 and omega-6 (n-6) polyunsaturated fatty acids (PUFAs) emerges. Hypothesizing that the rising positive correlation between monocyte chemoattractant protein 1 (MCP1) and n-6 in stage 4 could be the cause, we previously explored FGF23 and MCP1’s roles in dyslipidemia and cardiovascular risk in CKD. In the present paper, we retraced the study evaluating 40 kidney transplant patients (KTx), a cohort where several factors might modify the previous relationships found. An ELISA and gas chromatography assessed the MCP1, FGF23, and PUFA levels. Despite the FGF23 increase (p < 0.0001), low MCP1 levels were found. A decrease in the n-6/n-3 ratio (p = 0.042 CKD stage 4 vs. 5) lowered by the increase in both n-3 αlinolenic (p = 0.012) and docosapentaenoic acid (p = 0.049) was observed. A negative correlation between FGF23 and the n-6/n-3 ratio in CKD stage 4 (r2 −0.3 p = 0.043) and none with MCP1 appeared. According to our findings, different mechanisms in the relationship between FGF23, PUFAs, and MCP1 in CKD and KTx patients might be present, which is possibly related to the immunosuppressive status of the last. Future research will further clarify our hypothesis.
Young women were associated with higher risk of hypertensive disorders of pregnancy and cesarean section from hormone replaced cycles in frozen-thawed embryo transfer: a retrospective study of 5316 singleton deliveries

Background The utilization of frozen-thawed embryo transfer (FET) cycles has been linked to heightened risks of adverse perinatal outcomes. However, the potential association between adverse perinatal outcomes and distinct endometrial preparation regimens remains unclear. Therefore, we aim to investigate the maternal and neonatal outcomes after hormone replacement treatment (HRT) cycles, natural cycles (NC) and HRT cycles with pretreatment using GnRHa (HRT + GnRHa) for ovulatory women undergoing FET cycles. Methods A large sample retrospective cohort study was carried out from 2016 to 2020. The data included a total of 5316 women who had singleton deliveries undergoing FET cycles and which were divided into three groups based on different endometrial preparation protocols: 4399 patients in HRT groups, 621 in GnRHa+HRT groups, 296 in NC groups. The outcomes consisted of maternal outcomes (cesarean section, hypertensive disorders of pregnancy (HDP), placenta previa, gestational diabetes mellitus (GDM));and neonatal outcomes (preterm birth, newborn birthweight, low birthweight, small for gestational age (SGA), macrosomia, large for gestational age (LGA), fetal malformation). Results After adjusting for a series of confounding variables, we found an increased risk of HDP (aOR=3.362; 95%CI, 1.059-10.675) and cesarean section (aOR=1.838; 95%CI, 1.333-2.535) in HRT cycles compared with NC, especially for ovulatory women under 35 years old. However, in all three groups, newborn birth weight was not significantly different. Meanwhile, perinatal outcomes did not differ significantly in terms of perinatal outcomes in HRT +GnRHa cycles compared with HRT cycles solely. Conclusion During FET cycles, singletons from HRT were related to higher risks of HDP and cesarean section, particularly for young women. GnRHa pretreatment didn’t bring any benefit to perinatal outcomes compared with HRT cycles alone. Therefore, the natural cycle may be a more appropriate and safer option for young ovulatory women.
Immune Dysfunction from Radiation Exposure

The hematopoietic system is highly sensitive to ionizing radiation. Damage to the immune system may result in opportunistic infections and hemorrhage, which could lead to mortality. Inflammation triggered by tissue damage can also lead to additional local or widespread tissue damage. The immune system is responsible for tissue repair and restoration, which is made more challenging when it is in the process of self-recovery. Because of these challenges, the Radiation and Nuclear Countermeasures Program (RNCP) and the Basic Immunology Branch (BIB) under the Division of Allergy, Immunology, and Transplantation (DAIT) within the National Institute of Allergy and Infectious Diseases (NIAID), along with partners from the Biomedical Advanced Research and Development Authority (BARDA), and the Radiation Injury Treatment Network (RITN) sponsored a two-day meeting titled Immune Dysfunction from Radiation Exposure held on September 9–10, 2020. The intent was to discuss the manifestations and mechanisms of radiation-induced immune dysfunction in people and animals, identify knowledge gaps, and discuss possible treatments to restore immune function and enhance tissue repair after irradiation.
The Impact of Corporate Governance, Information Asymmetry and Sustainability Reporting: A Systematic Exploration

Sustainability reporting, integrated reporting and ESG reporting are the newest developments of reporting, suggesting by the many standard setters to overcome the problem by limiting non-financial information being disclosed by the organisation. The boards of directors determine the level, quality and magnitude of disclosure. The board's variation in knowledge, gender, capability, duality and competency will have different impacts on that decision. Whether the board of directors possessed proper enough knowledge to make decisions is questionable. It is because the managers might need to give more information to managers to make a decision, or even the director might not be asked important elements to the manager. This reciprocal effect impacts the level of disclosure. Due to that, the objective of this paper is to explore the potential of information asymmetry in the direction of corporate finance and sustainability reporting. This study uses advanced searching that systematically analyses. After the expert discussion, the findings can be divided into three themes: corporate governance, sustainability reporting and ESG reporting; corporate governance, information asymmetry, and information asymmetry.
Time‐calibrated phylogeny of Daphne (Thymelaeaceae): Pre‐mediterranean temporal origin of the sclerophyllous Daphne gnidium

The sclerophyllous syndrome is characterized by well‐defined traits (evergreen coriaceous leaves, inconspicuous flowers, and fleshy fruits). It has been hypothesized that lineages displaying the sclerophyllous syndrome show lower speciation rates than non‐sclerophyllous lineages after the establishment of the mediterranean climate. Daphne gnidium displays sclerophyllous traits and some differentiation into three subspecies (gnidium, mauritanica, maritima), but the spatio‐temporal origin of this taxonomic group is unknown due to the lack of a time‐calibrated phylogeny of the whole genus. Here, we inferred phylogenetic relationships and divergence times of Daphne (32 species, 238 samples) and other genera of Thymelaeaceae (16 genera, 38 species, 34 samples) using the internal transcribed spacer (ITS), which revealed that the current circumscription of Daphne is profoundly polyphyletic because some species are nested within the genera Wikstroemia and Edgeworthia. In contrast, D. gnidium formed a well‐supported clade as recognized in taxonomic accounts (subgenus Spachia). We found morphological and phylogenetic support for Daphne mauritanica as a monophyletic lineage sister to D. gnidium. Divergence between D. gnidium and D. mauritanica appears to have predated the establishment of seasonally dry conditions, which supports a pre‐mediterranean temporal origin of the lineage. A phylogeographical analysis within D. gnidium based on 66 nrDNA (ITS) and 84 cpDNA (rps16, trnV) sequences agreed with the low differentiation of the species in the Pleistocene despite its large distribution range. Altogether, D. gnidium illustrates one more example of the sclerophyllous syndrome with no speciation after the onset of the mediterranean climate.
Wave climate and storm systems on the Pacific northwest coast

Approved: Paul D. Komar A diverse assortment of wave measurement systems have been used along the Northwest coasts of Oregon and Washington. The present study compares wave data derived from these measurement systems to obtain a representative ocean wave climate for the region. Wave measurements have been derived from deep-water buoys of the National Data Buoy Center (NDBC) of NOAA, and from shallow-water pressure sensor arrays and deep-water buoys of the Coastal Data Information Program (CDIP) of Scripps Institution of Oceanography. Data have also been obtained for the past 20 years from a microseismometer system, a technique based on measuring seismic vibrations produced by ocean waves. Finally, the Wave Information Study (WIS) of the U.S. Army Corps of Engineers has produced 20+ years of wave data spanning 1956-75 from hindcasts based on daily weather charts. The deep-water wave climate is essentially uniform along the Pacific Northwest coastline, though there are some systematic differences between data sets. The NIDBP buoy yields wave heights that are roughly 8% higher than the two CDIP buoys. The microseismometer system yields wave heights in good agreement with the buoy data, but no trend is found when comparing wave periods which are systematically too high when derived from the microseismometer. Significant wave heights derived from WIS hindcast techniques are roughly 30-60% higher than measurements by the buoys. The data sets indicate a marked seasonality in the annual wave climate of the Pacific Northwest, with mean-monthly significant wave heights in the summer months ra.ngng from 1.25 to 1.75 meters, increasing to 2 to 3 meters in the winter months. Major Individual storms have yielded significant wave heights from 6 to 7 meters, with corresponding calculated wave breaker heights of 9 to 10 meters on Northwest beaches. Mean-monthly dominant wave periods range from 7 to 9 seconds during summer months, increasing to 11-13 seconds in winter months. Redacted for Privacy Due to the systematic differences between measured and hindcast wave heights, the WIS data could not be used to predict extreme-wave parameters. The largest storm waves measured during the 23-year continuous record of microseismometer and deepwater buoy measurements had a deep-water significant wave height of 7.3 meters. The projection of the 50and 100-year extreme wave heights for storms with heights exceeding 5 meters yields deep-water significant wave heights of 8.2 and 8.8 meters respectively. WAVE CLIMATE AND STORM SYSTEMS ON THE PACIFIC NORTHWEST COAST