Miracle-dz/UniFAR-FTUs huggingface dataset:
Specific Inadequate Nutrition and Acute Myocardial Infarction in NIS, Serbia

Introduction/Aim. Epidemiological investigation of risk factors for acute myocardial infarction (AMI) does not work is to primarily find new risk factors, as they have already identified a few hundred, but to investigate the representation in that area, in order to take appropriate preventive measures that could stop the further growth of diseased and dying from this disease. The aim of this study was to investigate the unhealthy nutrition as risk factor for acute myocardial infarction in examined population. Methods. A case-control study with 155 patients with a first myocardial infarction and 155 controls, matched with respect to sex and age (± 2 years) from the city of Niš, was used. Data was obtained throught the epidemiological questionnaire. Results. Number of servings (p=0,009), eating pieces of bread, white bread, consuming the meat and meat products more than 3 times per week (p for trend for all <0,001), eating fried foods, sweets and higher intake of eggs, as roasted as boiled was significantly higher in patients (p<0,001). Regular intake of food (p<0,001), eating dairy products (p<0,001), fresh fruit (p<0,001), and fresh vegetables (p<0,001) is significantly more often in healthy subjects. The use of fat was even in childhood in both groups (72,50% respectively 71,80%), but before disease, it was significantly more often in patients (p<0,001) as well as the use of oil (p<0,001). In the univariate model, as the strongest independent risk factor was the irregular nutrition (OR 14,217, p<0,001), used meat products more than 3 times a week (OR 9,525, p<0,001) and fried foods (OR 8,868, p<0,001). As a protective factor, frequent use of fresh vegetables (OR 0,333, p<0,001) and fresh fruit (OR 0,511, p=0,004). In the multivariate model as the strongest risk factor was the irregular nutrition (OR 47,839, p<0,001) and the use of the meat more than 3 times per week (OR 38,925, p<0,001). Conclusion. These findings are very important for further epidemiological research and should improve preventive strategies of this serious disorder in different geografical areas.
Does the Activity of the Combination of Imipenem and Colistin In Vitro Exceed the Problem of Resistance in Metallo- (cid:2) -Lactamase-Producing Klebsiella pneumoniae Isolates? (cid:1)

Using time-kill methodology, we investigated the interactions of an imipenem-colistin combination against 42 genetically distinct Klebsiella pneumoniae clinical isolates carrying a bla VIM-1 -type gene. Irrespective of the imipenem MIC, the combination was synergistic (50%) or indifferent (50%) against colistin-susceptible strains, while it was antagonistic (55.6%) and rarely synergistic (11%) against non-colistin-susceptible strains (with synergy being observed only against strains with colistin MICs of 3 to 4 (cid:1) g/ml). The combination showed improved bactericidal activity against isolates susceptible either to both agents or to colistin.
Sirolimus for progressive neuroﬁbromatosis type 1 – associated plexiform neuroﬁbromas: a Neuroﬁbromatosis Clinical Trials Consortium phase II study

(PNs) are nerve type 1 (NF1). They may cause signiﬁcant disﬁgurement, compression of vital structures, neurologic dysfunction, and/or pain. Currently, the only effective management strategy is surgical resection. Converging evidence has demonstrated that the NF1 tumor suppressor protein, neuroﬁbromin, negatively regulates activity in the mammalian Target of Rapamycin pathway. Methods. We employed a 2-strata clinical trial design. Stratum 1 included subjects with inoperable, NF1-associated progressive PN and sought to determine whether sirolimus safely and tolerably increases time to progression (TTP). Volumetric MRI analysis conducted at regular intervals was used to determine TTP relative to baseline imaging. Results. The estimated median TTP of subjects receiving sirolimus was 15.4 months (95% CI:14.3–23.7 mo), which was signiﬁcantly longer than 11.9 months ( P , .001), the median TTP of the placebo arm of a previous PN clinical trial with similar eligibility criteria. Conclusions. This study demonstrated that sirolimus prolongs TTP by almost 4 months in patients with NF1-associated progressive PN. Although the improvement in TTP is modest, given the lack of signiﬁcant or frequent toxicity and the availability of few other treatment options, the use of sirolimus to slow the growth of progressive PN could be considered in select patients.
Potential Indonesian Kenaf Varieties (Kenafindo) as Textile Raw Materials

Kenaf is a natural fiber-producing plant that is widely used as a raw material for making fiberboard (door-trim, car interior), particle board, fiber drain, geo-textile and high-quality paper. Kenaf ( Hisbiscus cannabinus ) produces fiber from its trunk, which is then classified as a bast fiber. Two new superior varieties of kenaf, Kenafindo 1 and Kenafindo 2 have the advantage of being less sensitive to the length of the daylight. Potential production of Kenafindo 1 and Kenafindo 2 is 2.5-4.5 tons of dry fiber / ha with fiber length of 225-235 cm, white fiber color (grade A), and fiber smoothness (smooth). Kenaf fiber lignin levels of Kenafindo 1 and Kenafindo 2 varieties were 9.36% and 7.26% respectively. Kenaf fiber Kenafindo 1 and Kenafindo 2 varieties have the opportunity as textile raw materials for garments. There are several advantages for using kenaf fiber as textile raw materials including good absorption, fire resistance and antimicrobial properties.
LINKING USER CONNECTEDNESS TO THE PERFORMANCE OF AN ENTERPRISE WITH A GLOBAL SUPPLY CHAIN: A CASE STUDY

The failure rate of enterprise resource planning systems is very high. Furthermore, many executives think that the implementation of the system might hurt the business due to implementation problems. This case study shows that the implementation of an ERP system can be accomplished and the system can achieve its expectations if the users are engaged and connected to the system. Once engaged in this way, employees at all levels can, in a piecemeal fashion, work out the issues or conform to the system. The author adds to theory by establishing propositions for user-system connectedness that results in growth by leveraging synergistic opportunities
Interleukin 1a Stimulates Lactate Dehydrogenase A Expression and Lactate Production in Cultured Porcine Sertoli Cells1

By using cultured porcine Sertoli cells as a model, the action of interleukin 1a (IL-1a) on lactate production and the site of this action were studied. IL-1a stimulated Sertoli cell lactate production in a timeand dose-dependent manner (with a halfmaximal effect [ED50] of 6 pM). Two major sites involved in IL1a action were identified. First, IL-1a was shown to increase the uptake of glucose substrate in a timeand dose-dependent manner. The maximal effect, with an ED50 of 10 pM, was observed after 24 h of treatment. Second, IL-1a increased the activity of the lactate dehydrogenase (LDH) A4 isoform, which is involved in the conversion of pyruvate into lactate. This increase in LDH A4 activity was detected at 12 h and was maximal, with an ED50 of 9 pM, after 24-h treatment with IL-1a. The increase was related to an increase in LDH A4 expression, since IL-1a stimulated LDH A mRNA (size: 1.5 kilobases, evidenced through Northern blotting analysis) in a doseand time-dependent manner. Assuming that IL-1a might be produced in the seminiferous tubules by both Sertoli and germ cells, which utilize lactate for their energy metabolism, we suggest that these results together show 1) that the cytokine may represent a signal in the metabolic cooperation existing between Sertoli cells and germ cells, and 2) that a redistribution of LDH isoforms in favor of LDH A4 under IL-1a control is a key mechanism(s) in such cooperation used by germ cells to enhance lactate production in Sertoli cells.
S0033291721001367jrv 1..14

Background. This study aimed to investigate general factors associated with prognosis regardless of the type of treatment received, for adults with depression in primary care. Methods. We searched Medline, Embase, PsycINFO and Cochrane Central (inception to 12/ 01/2020) for RCTs that included the most commonly used comprehensive measure of depressive and anxiety disorder symptoms and diagnoses, in primary care depression RCTs (the Revised Clinical Interview Schedule: CIS-R). Two-stage random-effects meta-analyses were conducted. Results. Twelve (n = 6024) of thirteen eligible studies (n = 6175) provided individual patient data. There was a 31% (95%CI: 25 to 37) difference in depressive symptoms at 3–4 months per standard deviation increase in baseline depressive symptoms. Four additional factors: the duration of anxiety; duration of depression; comorbid panic disorder; and a history of antidepressant treatment were also independently associated with poorer prognosis. There was evidence that the difference in prognosis when these factors were combined could be of clinical importance. Adding these variables improved the amount of variance explained in 3–4 month depressive symptoms from 16% using depressive symptom severity alone to 27%. Risk of bias (assessed with QUIPS) was low in all studies and quality (assessed with GRADE) was high. Sensitivity analyses did not alter our conclusions. Conclusions.When adults seek treatment for depression clinicians should routinely assess for the duration of anxiety, duration of depression, comorbid panic disorder, and a history of antidepressant treatment alongside depressive symptom severity. This could provide clinicians and patients with useful and desired information to elucidate prognosis and aid the clinical management of depression.
Predictive Factors for Complex Versus Simple Febrile Convulsion In Children

Background: Febrile seizure has a good prognosis, but may presented with status epilepticus and may raise the possibility of acquiring epilepsy later in life. These consequences are highly related to many features, including complex criteria. Objective: To investigate for factors which may be associated with increased incidence of complex febrile seizure. Patients and Methods: This is a cross-sectional comparative study done within 2013- 2014. The associations of febrile convulsion and its criteria with demographic and other characters of the patients were evaluated. Chi square was applied for statistical analysis. Results : Seventy six children were enrolled, male gender was 56.6% (n=43) and 39 (51.3%) of them were having complex febrile convulsion. There was no significant effect of age and sex on the type of febrile seizure; criteria of complex febrile seizure (prolonged, repetitive, and focal seizures) were unrelated among each other. Consanguinity marriage has a clear relationship with simple type (p value=.008), vaginal delivery was significantly associated with complex seizure (p value=0.047), non- respiratory causes of fever are associated with prolonged febrile seizure (p value= .024), while no differences between the types of febrile seizur regarding many other criteria, including anemia, body weight variations, previous febrile seizure, family history of febrile seizure, and others. Conclusion : There were only a few criteria predispose the child for complex febrile seizure, including non- respiratory causes of fever, vaginal delivery, non-consanguineous parents, and possibly prematurity; therefore complex febrile convulsion cannot be entirely predicted, but a trend can be expected if these mentioned factors were experienced.
University of Southern Denmark Increased Rate of Incidental Colorectal Malignant Polyps

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Role of Device Features towards Intention to Use of M-Commerce

Community College of QatarInformation Communication and Technology has undergone the spectacular development across the region, which has contributed to the world involvement of information and innovation together with the expansion of massive business growth. The advancement of technology and communication exposed people to vary option of device and facilities experience better daily life. Nowadays, people are becoming familiar with the rapid growth of technology through the usage of Internet and mobile device with better infrastructure. Device feature (DF) also was found to be one of the strongest predictors to use m-commerce among respondents. Device feature is referring to the device technology design characteristics which imply the user intention to adopt m-commerce. It might be because; the users are more concern to use the mobile device with user-friendly specification which allows them to view and experience the m-commerce to the optimum level. The well performed device anticipated to offer a better experience in using m-commerce to the users. As mentioned earlier, the respondents involved are among youngsters or to be specific students where it is anticipated that this group of people who are more exposed to the technology advancement compared to earlier generations. Most of the respondents can be classified as generation Y which might explain to this finding where they concern to have better and suitable device to use m-commerce, which covers on the screen quality, the speed of the device also in term of access quality.
A Study on the Medicinal Chemistry of Curcuma Longa

Plants are the major source of drug in the modern as well as traditional system of medicine throughout the world. Curcuma longa belonging to the family Zingiberaceae, is a medicinally important perennial herb distributed throughout the tropical and subtropical regions of the world from sea level to 1200 m. Therapeutically, C. longa has been used for curing various diseases such as asthma, anemia, chronic bronchitis, fever, dysentery, cough, diabetes, diarrhea, eye disease, hepatitis, hysteria, indigestion, itching, leprosy, liver disorder, menstrual disorder, peptic ulcer, small pox, chicken pox, tonsillitis, urinary infection etc. The objective of the study was phytochemical screening of C. longa for highlighting the traditional uses and pharmacological properties of its rhizomes. The rhizomes were collected from Pokhara Metropolitan -3, Nadipur, Nepal in November 2019. The collected rhizomes were washed thoroughly, cut into pieces, shaded dried completely, grinded into fine powder, extracted by Soxhlet extractor, evaporated the extract to get dark orange residue. Phytochemical screening was conducted by using standard methods. Phytochemical analysis of methanolic and ethanolic rhizome extract of C. longa showed that it contained alkaloids, steroids, tannins, flavonoids, carbohydrates, cardiaic, glycosides, phytosterol, anthocyanin, emodins, diterpenes, leuco anthocyanin, anthroquinone, chalcones, phenols, coumarin and phlobatannin in methanolic extract but not in ethanolic. Previous pharmacological studies on C. longa showed that it possessed antiviral, antifungal, anticancer, antidepresent, antimalarial, antimicrobial, antioxidant, antiplatelet, antibacterial, antivenum, antimutagenic and anticarcenogenic activities. Further phytochemical analysis using solvents of different polarity is necessary to identify much more phytochemical constituents for highlighting pharmacological and traditional medicinal properties.
Research Online Research Online FAML: A generic metamodel for MAS development FAML: A generic metamodel for MAS development

Abstract In some areas of software engineering research, there are several metamodels claiming to capture the main issues. Though it is profitable to have variety at the beginning of a research field, after some time, the diversity of metamodels becomes an obstacle, for instance to the sharing of results between research groups. To reach consensus and unification of existing metamodels, metamodel-driven software language engineering can be applied. This paper illustrates an application of software language engineering in the agent-oriented software engineering research domain. Here, we introduce a relatively generic agent-oriented metamodel whose suitability for supporting modeling language development is demonstrated by evaluating it with respect to several existing methodology-specific metamodels. First, the metamodel is constructed by a combination of bottom-up and top-down analysis and best practice. The concepts thus obtained and their relationships are then evaluated by mapping to two agent-oriented metamodels: TAO and Islander. We then refine the metamodel by extending the comparisons with the metamodels implicit or explicit within five more extant agent-oriented approaches: Adelfe, PASSI, Gaia, INGENIAS, and Tropos. The resultant FAML metamodel is a potential candidate for future standardization as an important component for engineering an agent modeling language. Abstract —In some areas of software engineering research, there are several metamodels claiming to capture the main issues. Though it is profitable to have variety at the beginning of a research field, after some time, the diversity of metamodels becomes an obstacle, for instance to the sharing of results between research groups. To reach consensus and unification of existing metamodels, metamodel-driven software language engineering can be applied. This paper illustrates an application of software language engineering in the agent-oriented software engineering research domain. Here, we introduce a relatively generic agent-oriented metamodel whose suitability for supporting modeling language development is demonstrated by evaluating it with respect to several existing methodology-specific metamodels. First, the metamodel is constructed by a combination of bottom-up and top-down analysis and best practice. The concepts thus obtained and their relationships are then evaluated by mapping to two agent-oriented metamodels: TAO and Islander. We then refine the metamodel by extending the comparisons with the metamodels implicit or explicit within five more extant agent-oriented approaches: Adelfe, PASSI, Gaia, INGENIAS, and Tropos. The resultant FAML metamodel is a potential candidate for future standardization as an important component for engineering an agent modeling language.
Institutional Knowledge at Singapore Management University Institutional Knowledge at Singapore Management University Improved likelihood inferences for Weibull regression model Improved likelihood inferences for Weibull regression model

A general procedure is developed for bias-correcting the maximum likelihood estimators (MLEs) of the parameters of Weibull regression model with either complete or right-censored data. Following the bias correction, variance corrections and hence improved t -ratios for model parameters are presented. Potentially improved t -ratios for other reliability-related quantities are also discussed. Simulation results show that the proposed method is eﬀective in correcting the bias of the MLEs, and the resulted t -ratios generally improve over the regular t -ratios.
The Signiﬁcance of Nonmarital Cohabitation: Marital Status and Mental Health Beneﬁts Among Middle-Aged and Older Adults

Objectives. According to the 2000 Census, about 1.2 million persons over age 50 are currently cohabiting. Do these unmarried cohabiting partnerships provide adults with mental health beneﬁts that are similar to those enjoyed by marrieds? We extended prior work on marital status and depression by including cohabitation in our conceptualization of marital status. Methods. We used data from the 1998 Health and Retirement Study ( N ¼ 18,598) to examine the relationship between marital status and depressive symptoms among adults over age 50. We also examined gender differences in this association. Results. We found that cohabitors report more depressive symptoms, on average, than do marrieds, net of economic resources, social support, and physical health. Additional analyses revealed that only among men do cohabitors report signiﬁcantly higher depression scores. Cohabiting and married women as well as cohabiting men experience similar levels of depression, and all of these groups report levels that are signiﬁcantly higher than married men’s. Discussion. Our ﬁndings demonstrate the importance of accounting for nontraditional living arrangements among persons aged 50 and older. Cohabitation appears to be more consequential for men’s than women’s depressive symptoms.
Further deﬁning housekeeping, or “maintenance,” genes Focus on “A compendium of gene expression in normal human tissues”

HOUSEKEEPING GENES are constitutively expressed to maintain cellular function. As such, they are presumed to produce the minimally essential transcripts neces-sary for normal cellular physiology. With the advent of microarray technology, it has recently become possible to identify at least the “starter set” of housekeeping genes, as exempliﬁed by the work of Velculescu et al. (2), as well as by Warrington et al. (3) in a paper published in this journal previously. In that paper, Warrington et al. examined the expression of 7,000 full-length genes in 11 different human tissues, both adult and fetal, to determine the suite of transcripts that were commonly expressed throughout human de-velopment and in different tissues. They identiﬁed 535 transcripts via microarray hybridization as likely can-didates for housekeeping genes, or, as the authors proposed, “maintenance” genes. the ﬁndings this previous study Cluster analysis groups transcripts detect ﬂuctuations expression not Forty-seven transcripts between
ORGANIC RESIDUES IN ANCIENT POTTERY SHERDS FROM SITES IN JORDAN

This paper discusses the analysis of organic residues preserved in the fabric of twelve pottery sherds (two Bronze Age and ten Iron Age) excavated from three sites: Jneneh, Sahab and Tell Abu al-Kharaz. Gas chromatography-mass spectrometry was used for separation and identification of organic constituents. Conventional solvent extraction was used for the extraction of residues preserved in their fabrics. The analysis showed that five sherds out of the twelve preserve significant organic constituents derived from plant and animal sources. The results inform that plant oil (most likely olive oil) could have been introduced into four Iron Age vessels (three from Jneneh and one from Tell Abu al-Kharaz) while animal fat of unknown source could have been introduced into one Iron Age vessel from Sahab. Evidences of the availability and exploitation of plant materials, such as oils and animal fats during the Iron Age were also presented in this paper.
Connecting the Dots: Impact of CLIL on Vocabulary Size and Content Mastery in Higher Education

This study aimed at investigating the impact of Content and Language Integrated Learning (CLIL) on higher education students’ vocabulary size and content mastery. The study involved a sample of 58 students from Middle East College in Omanduring the academic year 2019-2020. The experimental group consisted of 28 students, while the control group consisted of 30 students. The research instruments included a vocabulary size test and a content mastery test. The results of this study revealed that there was no statistically significant difference between the control and the experimental groups’ scores in the vocabulary post-test and the delayed-test. However, the vocabulary learning gain of the experimental group was higher than that of the control group, which means that CLIL had a positive impact on students’ vocabulary size, but this impact was not statistically significant. Moreover, there were differences between the control and the experimental groups’ scores in the content mastery test in favor of the experimental group. However, they were not statistically significant.