Miracle-dz/UniFAR-FTUs huggingface dataset:
Effects of Sucrose and Gibberellic Acid on Growth and Survival of Local Potato (Solanum tuberosum L.) Varieties in vitro in Kenya

Tissue culture techniques’ have become useful technologies for producing disease & pest free seed potato (Solanum tuberosum L.) in the developed world. However, these techniques have yet to be standardized for locally produced potato varieties in Kenya. Developing countries can also use these innovations for rapid multiplication of popular local seed material through rooted apical cuttings generated from either plantlets or micro tubers. In vitro experiments were therefore conducted to determine the optimum concentration of sucrose and gibberellic acid for growth and survival of local potato varieties, namely, Shangi, Unica and Wanjiku. The explants were cultured in Murashige and Skoog (MS) media supplemented with sucrose at a concentration of 20, 30 and 40 gL-1, while gibberellic acid was applied at a concentration of 0.2, 0.5 and 1.0 mgL-1. The study was laid out in a completely randomized design (CRD). MS Medium with sucrose 40 gL-1and gibberellic acid 0.5 mgL-1 significantly enhanced shoot length, with the longest shoot (10.3cm) being recorded for Wanjiku. The same treatment also gave the highest plant survival of 90%. Murashige and Skoog media, added with 0.5 mgL-1 gibberellic acid along with 40 gL-1 sucrose is recommended for generating wanjiku, unica and shangi apical rooted cuttings because it gave the best improvement of in-vitro clonal growth.
Faecal Concentrations of Progesterone and 17β-Oestradiol of Female Malayan Tapir from Different Faecal Hormone Extraction Methods

Non-invasive hormone monitoring of endangered wildlife provides an essential tool to optimize breeding strategies, mainly in captive management. However, the protocol of reproductive hormone monitoring on pregnancy status using non-invasive faecal samples in Malayan tapir is still inconclusive. Therefore, we compared the metabolites reproductive hormones; 17β-oestradiol and progesterone in the faecal samples extracted using methods of Schwarzenberger et al. (1996) (Methods A and B), Brown et al. (2001) (Method C) and Shutt et al. (2012) (Method D) from pregnant and non-pregnant captive Malayan Tapir. Faecal samples from four female of Malayan Tapir (Tapirus indicus) were collected for five months at Sungai Dusun Wildlife Reserve (n = 2), Zoo Taiping (n = 1) and Zoo Negara (n = 1), Malaysia. Analysis by liquid chromatography-mass spectrometry (LCMS) confirmed that progesterone was detected in all fecal sample extracted by extraction Method A, while 17β-oestradiol was undetectable in all methods. The measurement of reproductive hormones for pregnancy status via Enzyme-Linked Immunosorbent Assay (ELISA) analysis showed no significant difference (p > 0.05) for progesterone between the fecal extraction methods. Yet the data obtained were not able to validate the pregnancy status, due to similarity in concentration for both pregnant and non-pregnant tapirs. While for 17β-oestradiol, significant results were observed in all extraction methods and in pregnancy status (p < 0.05). Method C was found to be the most reliable extraction method (p < 0.05) to indicate pregnancy status. From the results, it showed that solvent used, boiling process and multiphase extraction plays important role in fecal extraction process in Malayan Tapir.
Montreal Cognitive Assessment for Evaluating Cognitive Impairment in Subarachnoid Hemorrhage: A Systematic Review

Subarachnoid hemorrhage (SAH) is a severe condition with high mortality and extensive long-term morbidity. Although research has focused mainly on physical signs and disability for decades, in recent years, it has been increasingly recognized that cognitive and psychological impairments may be present in many patients with SAH, negatively impacting their quality of life. We performed a systematic review aiming to provide a comprehensive report on the diagnostic accuracy of the Montreal Cognitive Assessment (MoCA) test for evaluating the presence of cognitive impairment in patients with SAH. Using appropriate search terms, we searched five databases (PubMed, Scopus, PsychINFO, Web of Sciences, and Latin American and Caribbean Health Sciences Literature) up to January 2022. Two cross-sectional studies investigated the accuracy of MoCA in SAH patients in the subacute and chronic phase. We appraised the quality of the included studies using the Quality Assessment of Diagnostic Accuracy Studies 2 (QUADAS-2) criteria. The MoCA test provides information about general cognitive functioning disturbances. However, a lower threshold than the original cutoff might be needed as it improves diagnostic accuracy, lowering the false positive rates. Further research is necessary for an evidence-based decision to use the MoCA in SAH patients.
The Theory of Social Situations: An Alternative Game-Theoretic Approach

Preface 1. Overview 2. The theory of social situations 3. Examples 4. Abstract stable sets 5. Existence and uniqueness of OSSB and CSSB 6. Characteristic function form games 7. Normal form games 8. Extensive form games with perfect information 9. Infinitely repeated games 10. Implementation by means of situations 11. Closing remarks References Index.
A disaster classification application using convolutional neural network by performing data augmentation

Natural disasters are catastrophic events and cause havoc to human life. These events occur in the most unpredictable times and are beyond human control. The aftermath of the disasters is devastating ranging from loss of life to relocation of large groups of the population. With the development in the domains of computer vision (CV) and Image processing, machine learning and deep learning models can integrate images and perform predictions. Deep learning techniques employ many robust techniques and provide significant results even in the case of images. The detection of natural disasters without human intervention requires the help of deep learning techniques. The project aims to employ a multi-layered convolutional neural network (CNN) organization to classify the images related to natural disasters related to earthquakes, floods, cyclones, and wildfires.
Dynamic Consistency and Ambiguity: A Reappraisal

It is commonly argued that dynamic consistency, consequentialism and non-expected utility are incompatible. The first aim of this paper is to rebut such arguments, by targeting the implicit assumption that the relevant contingencies correspond to objective resolutions of uncertainty (that is, events in a state space). These are not necessarily the same as the contingencies that the decision maker envisages, and we argue that any reasonable notion of dynamic consistency involves the latter, rather than the former, sort of contingency. We formulate such a version of dynamic consistency and show it to be compatible with consequentialism and non-expected utility. We then analyze the economic consequences of this new perspective. On the one hand, it provides a principled justification for restrictions on non-expected utility models (such as that proposed by Epstein and Schneider (2003)) in applications to dynamic choice problems. On the other hand, it provides a new analysis of the issue of attitude to information; contra standard arguments, the value of information under non-expected utility is non-negative as long as the information offered does not compromise information that the decision maker had otherwise expected to receive. Finally, we give a representation theorem for the contingencies the decision maker envisages, in the case where he uses the maxmin expected utility rule.
Work as a Social Determinant of Racial Health Inequalities

Interdisciplinary research posits that work is a social determinant of health contributing to racial inequalities in death, disease, and well-being amongst Black individuals in the United States. This study aims to advance research by integrating two theoretical frameworks (Warr’s Vitamin Model and Assari’s “differential exposure” and “differential gain” mechanisms) to investigate the role of work in eudemonic well-being. We included a nationally representative sample of adults who participated in the Midlife in the United States (MIDUS) Refresher and Milwaukee Refresher projects in 2011–2014, alongside corresponding occupational information (O*NET 17.0). The results of this study indicated that three of nine studied job characteristics systematically differ by race. We found evidence of differential gain by race on psychological well-being. Job characteristics had either benign or negative associations with well-being among Black individuals but consistently positive associations with well-being among non-Black individuals. In contrast to Warr’s Vitamin Model, we found little evidence of curvilinear health effects of job characteristics (only 5.5% were statistically significant). Finally, it was found that advanced educational attainment benefited multiple dimensions of well-being among Black individuals but had benign or negative implications for non-Black individuals, after controlling for demographics. Overall, the results highlight racial inequalities in eudemonic well-being because Black individuals face challenges in obtaining jobs that are beneficial to well-being. Collectively, the results reinforce the idea that work is a social determinant of health.
Bargaining with gendered egalitarianism. A transnational compensatory patriarchy in Polish Catholic Missions in England, Belgium, Sweden

Abstract The article examines the transformations of masculine formal (ordained) power in the Polish migrant religious organisations of the Roman Catholic Church. Based on qualitative in-depth interviews with 97 transmigrant women and men (consecrated and lay activists) involved in 14 Polish Catholic Mission organisations in England, Belgium and Sweden, the article gives an insight into various criticisms of patterns of priests’ patriarchal power in the Polish structures of the Roman Catholic Church. The analysis highlights how such power transforms in a transnational context when these organisations have to adapt to and function in more egalitarian, pluralistic and secularised Church organisational cultures than in the more patriarchal culture of Poland. We argue that the transnational context reinforces patriarchal models, albeit in a changed, hybrid form that we call ‘transnational compensatory patriarchy’. Our contribution to the discussion on the gendered transformation of power in transnational religious organisations focuses on two issues. First, we analyse the under-researched transformation of the patterns of masculine formal power in religious migrant organisations. Second, we show through a concept that we call ‘bargaining with egalitarianism’ how patriarchal power isomorphically (and hybridically) adapts itself to the more egalitarian context without losing its patriarchalism, which operates in the sending country. Therefore, we indicate the complexity and ambivalence of the transformation of masculine power by pointing to its intersectional sources and various ways of changing gender regimes.
The burden of colon cancer attributable to modifiable factors—The Norwegian Women and Cancer Study

Colon cancer is the second most frequently diagnosed cancer in women in Norway, where incidence rates of colon cancer increased 3‐fold between 1955 and 2014, for unknown reasons. We aimed to assess the burden of colon cancer attributable to modifiable risk factors in Norwegian women using the data from the Norwegian Women and Cancer (NOWAC) study. Self‐reported information from 35 525 women from the NOWAC study were available. These included the following exposures: smoking status, alcohol consumption, body mass index, physical activity, intake of calcium, fibers, and red and processed meat. Colon cancer cases were identified from the Cancer Registry of Norway. A parametric piecewise constant hazards model was used to estimate the strength of exposure‐cancer associations. Population attributable fractions with 95% confidence intervals (CIs) were calculated considering competing risk of death. The fraction of incident colon cancer attributable to ever smoking was 18.7% (95% CI 4.7%‐30.6%), low physical activity 10.8% (95% CI −0.7% to 21.0%), alcohol consumption 14.5% (95% CI −2.8% to 28.9%), and low intake of calcium 10.0% (95% CI −7.8% to 24.8%). A small proportion of colon cancer cases was attributable to combined intake of red and processed meat over 500 g/week, overweight/obesity, and low intake of fibers. Jointly, these seven risk factors could explain 46.0% (95% CI 23.0%‐62.4%) of the colon cancer incidence burden. Between 23% and 62% of the colon cancer burden among women in Norway was attributable to modifiable risk factors, indicating an important preventive potential of a healthy lifestyle.
PI3K/mTOR Dual Inhibitor Pictilisib Stably Binds to Site I of Human Serum Albumin as Observed by Computer Simulation, Multispectroscopic, and Microscopic Studies

Pictilisib (GDC-0941) is a well-known dual inhibitor of class I PI3K and mTOR and is presently undergoing phase 2 clinical trials for cancer treatment. The present work investigated the dynamic behaviors and interaction mechanism between GDC-0941 and human serum albumin (HSA). Molecular docking and MD trajectory analyses revealed that GDC-0941 bound to HSA and that the binding site was positioned in subdomain IIA at Sudlow’s site I of HSA. The fluorescence intensity of HSA was strongly quenched by GDC-0941, and results showed that the HSA–GDC-0941 interaction was a static process caused by ground-state complex formation. The association constant of the HSA–GDC-0941 complex was approximately 105 M−1, reflecting moderate affinity. Thermodynamic analysis conclusions were identical with MD simulation results, which revealed that van der Waals interactions were the vital forces involved in the binding process. CD, synchronous, and 3D fluorescence spectroscopic results revealed that GDC-0941 induced the structural change in HSA. Moreover, the conformational change of HSA affected its molecular sizes, as evidenced by AFM. This work provides a useful research strategy for exploring the interaction of GDC-0941 with HSA, thus helping in the understanding of the transport and delivery of dual inhibitors in the blood circulation system.
Production of Alternative Fuels Based on Municipal Sewage Sludge and Selected Types of ELV Waste

The construction of new wastewater treatment plants and the modernization of existing ones lead to the expansion of sewage networks, resulting in a sharp increase in the volume of municipal sewage sludge, which translates into a global problem of sludge management. The solution to this problem could be the recovery of energy from sewage sludge in the cement industry to exploit its energy potential. The aim of the present study was to examine the results of laboratory research on the production of alternative fuels based on municipal sewage sludge, plastic waste from end-of-life vehicles, and wood waste (sawdust) from carpentry enterprises. The tests were carried out for waste mixtures designated as PAZO I, PAZO II, PAZO III, and PAZO IV fuels, differing in the percentage of waste used and the type of plastic waste. The following parameters were evaluated in fuels: water content, ash content, sulfur content, and calorific value. Water content of the obtained fuels ranged from 17.1% to 19.4%, the ash content ranged from 2.5% to 3.4%, while PAZO II fuel was characterized by the highest ash content, which was 17.6%, but it remained within the limits permissible for alternative fuels.The sulfur and chlorine contents did not exceed the permissible values for alternative fuels. The calorific value of alternative fuels obtained was high and ranged from 16.5 MJ/kg to 33 MJ/kg. Furthermore, the composition of the individual fuel mixtures was selected to avoid energy-intensive sludge drying, whereas the fuel met the requirements for alternative fuels. The energy properties and water content of the obtained fuels indicate that the maximum amount of sewage sludge should not exceed 25% to maintain the parameters permissible for alternative fuels. Therefore, the analysis of the results leads to the conclusion that the obtained fuels, based on municipal sewage sludge, plastic waste, and wood waste (sawdust), meet the requirements for alternative fuels used in the cement industry. Today, the fuels based on municipal sewage sludge can be more of an alternative to conventional fuels used in the cement industry. The application of the fuels produced in the cement industry eliminates the formation of combustion byproducts in the form of slag and ash since they become a component of clinker. As an additional source of energy, the use of fuels in the cement industry will create an opportunity to move toward the circular economy.
Hsp90: From Cellular to Organismal Proteostasis

Assuring a healthy proteome is indispensable for survival and organismal health. Proteome disbalance and the loss of the proteostasis buffer are hallmarks of various diseases. The essential molecular chaperone Hsp90 is a regulator of the heat shock response via HSF1 and a stabilizer of a plethora of signaling proteins. In this review, we summarize the role of Hsp90 in the cellular and organismal regulation of proteome maintenance.
Adoption of Agroforestry Practices in and around the Luki Biosphere Reserve in the Democratic Republic of the Congo

Despite the technical, socio-economic and environmental challenges, indigenous subsistence agroforestry, generally referred to as slash-and-burn agriculture or bush-fallow farming, is a common practice for local populations in the Democratic Republic of Congo. This study analyzed the proportion of adopters and non-adopters, together with other factors that influence farmers’ choices of adopting agroforestry or that discourage its adoption in the Luki Biosphere Reserve (LBR) area. Data were collected through a survey of 390 households using a structured questionnaire. A logistic regression model, with SPSS Statistics software was fitted to the data against a binary response (1 = adopt; 0 = not adopt). The proportion of adopters of agroforestry practices in the LBR area far exceeds (more than three-fold) that of non-adopters. Six factors exert a positive and significant (p-value = 5%) effect on peasant decisions to adopt agroforestry practices in LBR, including age (51 to 60 years old), marital status, education level, main activity, land tenure and farmers’ membership in a local association. Gender, other age categories, household size, number of years of agroforestry experience, number of assets, distance between residence and fields, and access to credit did not positively influence the adoption of these practices. The results of this study would help engage the indigenous community with different sectors and disseminate agroforestry as a sustainable practice appropriate to the real needs of local populations.
Addressing the learning outcomes for professional skills using an integrated teaching strategy

Abstract Students at a South African university are exposed to an annual report project which combines elements of four courses as an integrated teaching strategy. The purpose of this paper is to report students’ perspectives as to the extent this integrated teaching strategy addressed the learning outcomes for professional skills as required by the International Education Standard 3 Initial professional development—professional skills (2015). The study used survey research to collect data from 74 students to determine students’ perspectives on whether the integrated teaching strategy addressed the learning outcomes. Students indicated that many of the professional skills listed in International Education Standard 3 are addressed by the integrated teaching strategy. In particular, interpersonal and communication skills were rated as the highest skills acquired, in particular teamwork and communication skills, followed by organisational skills, intellectual skills and personal skills. There were some significant statistical differences for some of the skills between the perspectives of the students when the results were sorted on a gender basis and a language basis. Where some skills were not highly rated by the students, it may be that these skills were not wholly needed by students to complete the integrated project. However, overall, students rated the majority of the skills above the midpoint of the rating scale which suggests that students saw the integrated teaching strategy capable of developing the professional skills investigated in this study.
Design and analysis of an efficient glaucoma model for evaluation of pharmacological trials

: Glaucoma is a multifactorial progressive optic neuropathy whose main risk factor is intraocular hypertension (IOH). It generates loss of nerves and is the primary cause of irreversible blindness worldwide. The objective of this work was to develop a glaucoma model in rabbits and analyze the anatomical, functional and biochemical changes over time through intraocular pressure (IOP), electroretinography (ERG), antioxidant capacity with FRAP essay. in aqueous humor (AH), and histopathology with quantification of retinal ganglion cells (RGC). 24 female New Zealand white rabbits were used. In 12 animals, glaucoma was induced by injection of (cid:181)(cid:181)(cid:181)(cid:181)(cid:181) -chymotrypsin. During the postoperative period, the treatment and control groups were examined weekly. 7 days after surgery, IOP (mmHg) was 18.30 ± 1.75 in the treatment group and 13.59 ± 0.63 in the control (p<0.02). The most important rise was at 14 days (treatment 27 ± 2.64 vs. controls 15.78 ± 0.86) (p<0.001), remaining stable thereafter. In the ERG, the analysis of the latency of A and B waves in ms with stimulus intensity of 15 LUX showed a difference between treatment and controls (p £££££ 0.05). The FRAP values ( mmmmm M FeSO 4 /mg of proteins) were 520.3 ± 44 in the treatment group, and 2851.3 ± 178.7 in the control (p<0.0001). The RGC count per field was 15 ± 2.20 in the control group and 5.52 ± 0.77 in the treatment group (p<0.001). The glaucoma model enabled the analysis of anatomical, functional and biochemical changes as a function of time.
Effect of fillets on a blade/vane of wave energy harvesting impulse turbine

Fillets on leading edges (LE) of turbine blades alter flow patterns and change the loss profile. A bidirectional flow impulse turbine utilized for harnessing wave energy is introduced and computational fluid dynamics (CFD) was used to perform various analysis. In the present work, fillets of different radii on the leading and trailing edges of both the rotor blade (RB) and guide vane (GV) are modified to study the change in overall performance. After an appropriate gird convergence study, ANSYS-CFX 16.0 solver is used for solving the Reynolds averaged Navier-Stokes (RANS) equations incorporating the k-ω-SST turbulence closure model. The numerical investigations were performed using the high-resolution scheme with the convergence criteria of 10−6 to produce unwavering results. The results show that the boundary layer near the endwall creates flow blockage and losses. Also, the increase in pressure drop due to the thickening of the boundary layers (BLs) across the blade/vane leads to a depletion in the overall performance of the turbine. The rotor and guide vane filleted turbine experience higher losses than the base model due to the radial pressure gradient that is explained with post-processed figures. The concept of fillet shapes has been applied to gas turbines and which improves the performance of the turbine due to a reduction in the secondary flow losses occurring inside the turbine and the same concept has been applied to wave energy air turbine to check its performance based on the losses present across the turbine passage.